# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- WD40 PF00400.32 EKX30741.1 - 1.3e-08 35.4 4.4 9.2e-06 26.3 0.1 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat FG-GAP_2 PF14312.6 EKX30741.1 - 0.023 14.9 1.6 0.67 10.3 0.2 2.2 2 0 0 2 2 2 0 FG-GAP repeat IQ PF00612.27 EKX30742.1 - 7.3e-08 31.5 3.0 5.5e-05 22.6 0.2 2.2 2 0 0 2 2 2 2 IQ calmodulin-binding motif RNA_pol_Rpc4 PF05132.14 EKX30744.1 - 0.0061 17.0 1.6 0.0061 17.0 1.6 1.2 1 0 0 1 1 1 1 RNA polymerase III RPC4 SDA1 PF05285.12 EKX30744.1 - 0.014 14.8 30.2 0.015 14.8 30.2 1.1 1 0 0 1 1 1 0 SDA1 SpoIIIAH PF12685.7 EKX30744.1 - 0.049 13.5 8.8 0.05 13.4 8.8 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Lum_binding PF00677.17 EKX30744.1 - 0.092 12.7 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Lumazine binding domain Zip PF02535.22 EKX30744.1 - 0.18 10.9 2.5 0.16 11.2 2.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DNA_pol_phi PF04931.13 EKX30744.1 - 0.3 9.1 48.6 0.32 9.1 48.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi eIF-3c_N PF05470.12 EKX30744.1 - 0.33 9.2 12.0 0.34 9.2 12.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Nop14 PF04147.12 EKX30744.1 - 0.35 9.0 37.4 0.35 9.0 37.4 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 EKX30744.1 - 0.35 9.6 12.8 0.4 9.4 12.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mpp10 PF04006.12 EKX30744.1 - 0.48 8.8 32.1 0.52 8.7 32.1 1.1 1 0 0 1 1 1 0 Mpp10 protein CobT PF06213.12 EKX30744.1 - 0.96 8.8 31.8 1.1 8.7 31.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Presenilin PF01080.17 EKX30744.1 - 1.1 8.0 5.4 1 8.0 5.4 1.1 1 0 0 1 1 1 0 Presenilin SpoIIP PF07454.11 EKX30744.1 - 1.1 8.6 9.8 1.2 8.5 9.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF913 PF06025.12 EKX30744.1 - 1.3 7.9 10.8 1.5 7.7 10.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Tim54 PF11711.8 EKX30744.1 - 1.6 7.4 12.0 1.8 7.3 12.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 BUD22 PF09073.10 EKX30744.1 - 1.6 8.0 29.8 1.7 7.9 29.8 1.1 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 EKX30744.1 - 1.8 7.0 27.0 1.9 6.9 27.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RNA_polI_A34 PF08208.11 EKX30744.1 - 1.8 8.6 13.8 2 8.5 13.8 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF2151 PF10221.9 EKX30744.1 - 2.3 6.7 6.3 2.4 6.6 6.3 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Trypan_PARP PF05887.11 EKX30744.1 - 2.4 8.1 24.4 3 7.8 24.4 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CDC45 PF02724.14 EKX30744.1 - 2.6 6.2 28.8 2.9 6.1 28.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Connexin PF00029.19 EKX30744.1 - 2.9 7.6 5.3 3.6 7.3 5.3 1.1 1 0 0 1 1 1 0 Connexin NPR3 PF03666.13 EKX30744.1 - 3.8 6.2 11.7 3.9 6.1 11.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3899 PF13038.6 EKX30744.1 - 7.7 7.1 0.0 7.7 7.1 0.0 3.0 2 1 0 2 2 1 0 Domain of unknown function (DUF3899) RR_TM4-6 PF06459.12 EKX30744.1 - 9.8 5.9 13.9 12 5.6 13.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neuralized PF07177.12 EKX30746.1 - 4.6e-05 23.5 0.0 4.6e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Neuralized SPRY PF00622.28 EKX30746.1 - 0.00039 20.5 0.0 0.00043 20.4 0.0 1.1 1 0 0 1 1 1 1 SPRY domain Bromodomain PF00439.25 EKX30747.1 - 2.6e-18 65.9 1.4 3.7e-18 65.4 1.1 1.4 1 1 0 1 1 1 1 Bromodomain Pkinase PF00069.25 EKX30749.1 - 5.6e-27 94.8 0.0 1e-25 90.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX30749.1 - 2.6e-12 46.6 0.0 1.3e-05 24.7 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EKX30749.1 - 0.0099 15.2 0.1 2.5 7.3 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Ureidogly_lyase PF04115.12 EKX30750.1 - 0.13 12.0 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Ureidoglycolate lyase Ephrin_rec_like PF07699.13 EKX30751.1 - 6.8e-25 86.6 55.1 1.4e-09 37.5 4.8 6.6 6 1 1 7 7 7 5 Putative ephrin-receptor like NCD3G PF07562.14 EKX30751.1 - 1.7e-06 27.9 44.4 0.00041 20.2 1.7 5.7 6 1 0 6 6 6 3 Nine Cysteines Domain of family 3 GPCR EGF_MSP1_1 PF12946.7 EKX30751.1 - 0.026 14.6 9.5 3.1 7.9 0.0 4.6 4 1 0 4 4 4 0 MSP1 EGF domain 1 Pico_P2A PF00947.19 EKX30751.1 - 2.5 8.1 12.7 10 6.2 0.4 4.0 3 1 1 4 4 4 0 Picornavirus core protein 2A YjgF_endoribonc PF14588.6 EKX30752.1 - 9.1e-29 100.5 0.0 1e-28 100.3 0.0 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 EKX30752.1 - 2e-14 53.6 0.1 1e-13 51.3 0.1 1.8 1 1 0 1 1 1 1 Endoribonuclease L-PSP PhoR PF11808.8 EKX30754.1 - 0.67 10.4 0.0 0.67 10.4 0.0 2.5 3 0 0 3 3 3 0 Phosphate regulon sensor protein PhoR DUF4834 PF16118.5 EKX30754.1 - 8.6 7.4 0.0 8.6 7.4 0.0 5.1 3 2 1 4 4 4 0 Domain of unknown function (DUF4834) SID-1_RNA_chan PF13965.6 EKX30754.1 - 8.7 4.6 14.7 2.2 6.6 0.5 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Glyco_tran_28_C PF04101.16 EKX30755.1 - 6.4e-14 52.3 0.1 8.8e-14 51.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_4 PF13692.6 EKX30755.1 - 0.00011 22.7 0.1 0.00015 22.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EKX30755.1 - 0.0012 18.4 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 MGDG_synth PF06925.11 EKX30755.1 - 0.002 18.3 0.1 0.0052 16.9 0.0 1.7 2 0 0 2 2 2 1 Monogalactosyldiacylglycerol (MGDG) synthase HyaE PF07449.11 EKX30755.1 - 0.033 14.1 0.0 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE AAA_33 PF13671.6 EKX30756.1 - 3.4e-13 50.0 0.7 2.7e-06 27.6 0.0 2.3 1 1 1 2 2 2 2 AAA domain KTI12 PF08433.10 EKX30756.1 - 1e-05 25.2 0.5 0.0076 15.7 0.1 2.1 1 1 1 2 2 2 2 Chromatin associated protein KTI12 AAA_22 PF13401.6 EKX30756.1 - 0.0009 19.5 0.0 0.0014 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EKX30756.1 - 0.0013 18.1 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 EKX30756.1 - 0.0026 18.3 0.3 0.056 14.0 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EKX30756.1 - 0.03 14.7 0.0 0.057 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 EKX30756.1 - 0.032 13.9 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Ploopntkinase1 PF18748.1 EKX30756.1 - 0.1 12.1 0.0 2.5 7.6 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 YebO PF13974.6 EKX30758.1 - 1.8 8.7 5.5 1 9.5 2.0 2.1 1 1 1 2 2 2 0 YebO-like protein RRM_1 PF00076.22 EKX30760.1 - 1.4e-41 140.2 0.0 8e-20 70.4 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EKX30760.1 - 2.6e-05 24.3 0.0 0.0015 18.6 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 EKX30760.1 - 0.00053 19.6 0.0 0.093 12.3 0.0 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 EKX30760.1 - 0.002 17.7 0.2 1.5 8.6 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease B OB domain Limkain-b1 PF11608.8 EKX30760.1 - 0.017 15.2 0.0 1.9 8.6 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 Pro_CA PF00484.19 EKX30761.1 - 4.8e-34 117.9 0.1 5.4e-34 117.7 0.1 1.0 1 0 0 1 1 1 1 Carbonic anhydrase BBL5 PF07289.11 EKX30762.1 - 0.092 11.8 0.2 0.13 11.3 0.2 1.2 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein NUDIX PF00293.28 EKX30763.1 - 7.5e-23 81.0 0.1 1.2e-22 80.4 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain Isochorismatase PF00857.20 EKX30763.1 - 0.22 11.7 0.0 0.39 10.9 0.0 1.3 1 0 0 1 1 1 0 Isochorismatase family HEAT PF02985.22 EKX30764.1 - 6.8e-12 44.6 0.2 0.013 15.7 0.0 3.3 3 0 0 3 3 3 3 HEAT repeat HEAT_2 PF13646.6 EKX30764.1 - 2.1e-08 34.4 0.0 1.6e-05 25.2 0.0 2.2 1 1 0 2 2 2 2 HEAT repeats Arm PF00514.23 EKX30764.1 - 5.5e-08 32.6 0.3 0.00024 21.0 0.0 3.1 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EKX30764.1 - 1.6e-07 31.6 0.5 0.00026 21.4 0.0 3.1 2 1 1 3 3 3 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EKX30764.1 - 0.0024 18.5 0.0 0.47 11.1 0.0 2.5 1 1 2 3 3 3 1 Vacuolar 14 Fab1-binding region Pkinase_Tyr PF07714.17 EKX30765.1 - 6.3e-43 146.9 0.0 7.9e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX30765.1 - 9.1e-22 77.7 0.0 1.1e-21 77.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Phage_T4_gp36 PF03903.13 EKX30765.1 - 0.066 13.2 0.0 0.089 12.8 0.0 1.2 1 0 0 1 1 1 0 Phage T4 tail fibre Ank_4 PF13637.6 EKX30766.1 - 3.9e-17 62.4 0.0 4.6e-08 33.5 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX30766.1 - 1.1e-16 60.5 0.1 2.8e-08 33.9 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 EKX30766.1 - 7.2e-15 55.3 0.1 9.3e-15 55.0 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX30766.1 - 5.8e-14 52.0 0.2 3.8e-09 36.6 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX30766.1 - 6.8e-13 47.6 0.0 1.8e-06 27.8 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat DUF1844 PF08899.11 EKX30766.1 - 0.1 12.9 0.1 0.15 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1844) Ank_4 PF13637.6 EKX30767.1 - 7.8e-37 125.2 1.4 4.1e-07 30.4 0.1 6.5 6 1 1 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX30767.1 - 1.6e-35 121.5 3.9 1.9e-08 34.8 0.0 4.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX30767.1 - 2.2e-20 72.5 9.3 0.16 12.3 0.0 7.1 2 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX30767.1 - 1.4e-15 55.8 2.6 0.7 10.6 0.0 7.1 7 0 0 7 7 7 5 Ankyrin repeat RHH_5 PF07878.11 EKX30767.1 - 6.8e-12 45.1 10.9 1.1 9.2 0.1 7.1 7 0 0 7 7 7 5 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 Chol_subst-bind PF09129.11 EKX30767.1 - 6.4e-11 41.8 0.0 0.96 8.3 0.0 6.2 1 1 6 7 7 7 5 Cholesterol oxidase, substrate-binding Ank PF00023.30 EKX30767.1 - 1.1e-07 32.0 1.8 16 6.1 0.0 6.8 7 0 0 7 7 7 0 Ankyrin repeat zf-CCCH_6 PF18585.1 EKX30767.1 - 2e-05 24.4 5.1 31 4.5 0.1 7.4 6 3 1 7 7 7 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 eIF3_p135 PF12807.7 EKX30767.1 - 0.025 14.6 0.0 1.7 8.6 0.0 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit 135 AP_endonuc_2_N PF07582.12 EKX30767.1 - 0.053 13.2 10.0 52 3.7 0.0 5.6 7 0 0 7 7 7 0 AP endonuclease family 2 C terminus Sigma70_r1_2 PF00140.20 EKX30767.1 - 0.21 11.6 2.7 96 3.1 0.0 4.1 5 0 0 5 5 5 0 Sigma-70 factor, region 1.2 MerR-DNA-bind PF09278.11 EKX30767.1 - 0.31 11.6 6.2 1.5e+02 3.0 0.0 5.0 5 0 0 5 5 5 0 MerR, DNA binding VWA_3_C PF18571.1 EKX30767.1 - 5.7 6.9 7.4 1.6e+02 2.3 0.0 4.7 6 0 0 6 6 6 0 von Willebrand factor type A C-terminal domain Ank_4 PF13637.6 EKX30768.1 - 6.4e-10 39.4 0.0 2.2e-06 28.1 0.0 1.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX30768.1 - 7.6e-06 26.4 0.0 9.1e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX30768.1 - 1.3e-05 25.4 0.0 0.00051 20.4 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EKX30768.1 - 3.4e-05 23.9 0.0 0.005 17.2 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EKX30768.1 - 3.5e-05 24.0 0.2 0.019 15.3 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) TMEM219 PF14940.6 EKX30771.1 - 0.016 14.8 0.4 0.022 14.4 0.4 1.2 1 0 0 1 1 1 0 Transmembrane 219 DUF3449 PF11931.8 EKX30772.1 - 4.9e-19 68.8 0.1 5.3e-19 68.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) DUF4070 PF13282.6 EKX30772.1 - 0.04 14.0 0.0 0.055 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4070) RILP PF11461.8 EKX30773.1 - 0.11 12.7 0.3 0.24 11.6 0.3 1.5 1 0 0 1 1 1 0 Rab interacting lysosomal protein WD40 PF00400.32 EKX30774.1 - 4.3e-27 93.8 3.1 1.2e-07 32.3 0.1 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX30774.1 - 4.6e-07 30.0 0.0 0.0064 16.8 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EKX30774.1 - 0.022 14.1 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain DUF2835 PF11197.8 EKX30774.1 - 0.039 13.8 0.0 0.43 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2835) CBM_15 PF03426.14 EKX30774.1 - 0.084 12.5 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 15) Nup160 PF11715.8 EKX30774.1 - 0.19 10.4 0.0 3.1 6.3 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 TerC PF03741.16 EKX30779.1 - 9.6e-27 93.8 0.0 1.2e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Integral membrane protein TerC family DUF475 PF04332.15 EKX30779.1 - 0.0096 15.7 0.8 0.011 15.5 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF475) FAM176 PF14851.6 EKX30779.1 - 0.079 12.6 0.1 4 7.1 0.1 2.1 2 0 0 2 2 2 0 FAM176 family CDC45 PF02724.14 EKX30780.1 - 0.042 12.1 40.3 0.046 12.0 40.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 EKX30780.1 - 0.68 8.3 48.8 0.71 8.2 48.8 1.0 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 EKX30780.1 - 1 7.5 49.4 1.1 7.4 49.4 1.0 1 0 0 1 1 1 0 Nop14-like family CCSAP PF15748.5 EKX30780.1 - 2.9 8.0 25.9 3.2 7.8 25.9 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Pex14_N PF04695.13 EKX30780.1 - 3.1 8.4 10.7 4.2 8.0 10.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RR_TM4-6 PF06459.12 EKX30780.1 - 4.8 6.9 33.2 6.4 6.5 33.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Apt1 PF10351.9 EKX30780.1 - 8.7 5.1 20.5 9.4 5.0 20.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain PA PF02225.22 EKX30781.1 - 1.6e-07 31.2 0.4 4.9e-07 29.7 0.4 1.8 1 0 0 1 1 1 1 PA domain Ifi-6-16 PF06140.13 EKX30782.1 - 2.6e-15 56.1 40.0 2.6e-15 56.1 40.0 1.9 1 1 1 2 2 2 1 Interferon-induced 6-16 family CD20 PF04103.15 EKX30782.1 - 0.019 15.1 4.6 0.026 14.6 4.6 1.2 1 0 0 1 1 1 0 CD20-like family DUF4889 PF16230.5 EKX30782.1 - 0.16 12.2 0.1 0.27 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4889) Pkinase_Tyr PF07714.17 EKX30784.1 - 1.9e-69 233.9 0.0 2.1e-69 233.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX30784.1 - 1.2e-32 113.4 0.0 1.5e-32 113.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain ABATE PF07336.11 EKX30785.1 - 0.001 19.7 2.5 0.0019 18.9 2.5 1.5 1 1 0 1 1 1 1 Putative stress-induced transcription regulator HetR_C PF18460.1 EKX30785.1 - 0.15 12.0 6.1 2.1 8.3 1.0 2.8 3 0 0 3 3 3 0 Heterocyst differentiation regulator C-terminal Hood domain ERM PF00769.19 EKX30785.1 - 0.39 10.5 27.8 0.076 12.8 24.3 1.6 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DinB_2 PF12867.7 EKX30785.1 - 4 8.0 6.6 11 6.6 0.0 3.5 2 1 0 2 2 2 0 DinB superfamily DUF1664 PF07889.12 EKX30785.1 - 4.9 7.2 16.7 0.72 9.9 2.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF488 PF04343.13 EKX30785.1 - 6.4 7.4 9.8 1.2 9.7 4.1 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF488 Fz PF01392.22 EKX30787.1 - 1.5e-06 28.7 3.6 3.7e-06 27.5 3.6 1.6 1 0 0 1 1 1 1 Fz domain UNC-79 PF14776.6 EKX30787.1 - 1.9 7.1 5.8 3.3 6.4 5.8 1.3 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 PAP2_C PF14360.6 EKX30788.1 - 1.1e-05 25.9 1.2 1.1e-05 25.9 1.2 2.7 3 0 0 3 3 3 1 PAP2 superfamily C-terminal RVT_1 PF00078.27 EKX30791.1 - 0.0031 17.0 0.0 2.1 7.8 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) ORC5_C PF14630.6 EKX30791.1 - 0.007 15.9 0.2 0.011 15.3 0.2 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus Maf PF02545.14 EKX30792.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 Maf-like protein WW PF00397.26 EKX30793.1 - 2.4e-10 40.3 2.5 4.5e-10 39.4 2.5 1.5 1 0 0 1 1 1 1 WW domain Creatininase PF02633.14 EKX30794.1 - 2.4 7.5 13.5 0.58 9.6 4.0 2.6 2 1 0 2 2 2 0 Creatinine amidohydrolase Sp38 PF07354.12 EKX30794.1 - 2.8 7.3 4.8 0.61 9.5 0.5 2.0 2 0 0 2 2 2 0 Zona-pellucida-binding protein (Sp38) DUF1878 PF08963.10 EKX30795.1 - 0.019 15.5 0.7 0.019 15.5 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1878) PPR_2 PF13041.6 EKX30797.1 - 1.1e-16 60.8 0.9 9.4e-10 38.5 0.0 2.8 2 1 1 3 3 3 3 PPR repeat family PPR_3 PF13812.6 EKX30797.1 - 1.4e-13 50.6 0.3 2.6e-07 30.6 0.0 2.1 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_long PF17177.4 EKX30797.1 - 4.2e-11 42.6 0.3 4.7e-11 42.4 0.3 1.0 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EKX30797.1 - 2.9e-06 27.1 6.1 0.069 13.4 0.0 3.7 4 0 0 4 4 4 3 PPR repeat PPR_1 PF12854.7 EKX30797.1 - 8.1e-06 25.4 10.7 0.01 15.5 0.3 3.7 4 1 0 4 4 4 2 PPR repeat C2 PF00168.30 EKX30798.1 - 5.3e-15 55.6 0.0 6.3e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 C2 domain Surp PF01805.20 EKX30799.1 - 1.6e-13 50.4 0.1 3.4e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 Surp module CTD_bind PF04818.13 EKX30799.1 - 8.6e-12 45.7 0.3 2.3e-11 44.4 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Mur_ligase_M PF08245.12 EKX30801.1 - 6.8e-11 42.5 0.2 1.4e-08 34.9 0.1 2.3 1 1 1 2 2 2 2 Mur ligase middle domain Mur_ligase_C PF02875.21 EKX30801.1 - 3.9e-05 23.8 0.0 0.0001 22.5 0.0 1.8 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain OsmC PF02566.19 EKX30801.1 - 0.015 15.8 1.5 6.2 7.4 0.2 2.5 2 0 0 2 2 2 0 OsmC-like protein Shadoo PF14999.6 EKX30801.1 - 0.56 10.3 5.9 3.8 7.6 0.2 2.9 3 0 0 3 3 3 0 Shadow of prion protein, neuroprotective HAD_SAK_2 PF18143.1 EKX30802.1 - 7.5e-05 23.1 0.4 0.00015 22.1 0.0 1.7 2 1 0 2 2 2 1 HAD domain in Swiss Army Knife RNA repair proteins DUF3584 PF12128.8 EKX30802.1 - 5.9 4.3 13.3 7.7 3.9 13.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Presenilin PF01080.17 EKX30802.1 - 7.4 5.2 5.1 8.4 5.0 5.1 1.1 1 0 0 1 1 1 0 Presenilin BRCT PF00533.26 EKX30803.1 - 4.4e-06 27.0 0.0 9.3e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EKX30803.1 - 0.0041 17.5 0.0 0.0087 16.4 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DsbC_N PF10411.9 EKX30803.1 - 0.057 12.9 0.0 19 4.8 0.0 2.8 1 1 2 3 3 3 0 Disulfide bond isomerase protein N-terminus DUF3408 PF11888.8 EKX30803.1 - 0.12 12.5 1.8 0.2 11.8 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Dicty_REP PF05086.12 EKX30804.1 - 0.32 8.9 1.1 0.32 8.9 1.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PBP1_TM PF14812.6 EKX30804.1 - 3.9 7.9 10.8 11 6.5 10.8 1.8 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Imm49 PF15575.6 EKX30805.1 - 0.033 14.0 0.1 0.038 13.7 0.1 1.1 1 0 0 1 1 1 0 Immunity protein 49 Pkinase_Tyr PF07714.17 EKX30806.1 - 2.8e-48 164.5 0.0 3.4e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX30806.1 - 1.4e-18 67.3 0.0 1.7e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain ECSIT_C PF14784.6 EKX30807.1 - 0.00025 21.4 9.6 12 6.2 0.1 5.1 1 1 4 5 5 5 4 C-terminal domain of the ECSIT protein DUF4361 PF14274.6 EKX30807.1 - 0.0015 18.9 10.4 9.5 6.5 0.2 4.8 1 1 2 3 3 3 2 Domain of unknown function (DUF4361) Peptidase_C14 PF00656.22 EKX30807.1 - 0.0057 16.6 16.5 4.5 7.2 0.3 4.7 1 1 3 4 4 4 3 Caspase domain DUF4696 PF15767.5 EKX30807.1 - 0.069 11.7 30.5 0.65 8.5 8.5 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4696) DUF4488 PF14869.6 EKX30807.1 - 0.091 12.7 12.0 32 4.5 0.7 5.4 1 1 5 6 6 6 0 Domain of unknown function (DUF4488) RVT_1 PF00078.27 EKX30809.1 - 4.7e-16 59.0 0.0 5.4e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Bac_DNA_binding PF00216.21 EKX30809.1 - 0.094 12.9 0.0 0.34 11.2 0.0 1.8 2 0 0 2 2 2 0 Bacterial DNA-binding protein Ank_4 PF13637.6 EKX30810.1 - 3.8e-46 154.9 4.8 9.7e-12 45.2 0.1 8.2 8 0 0 8 8 8 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX30810.1 - 6.7e-39 132.3 0.2 3.6e-08 33.9 0.0 5.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX30810.1 - 8.2e-24 81.1 0.6 0.0012 19.2 0.0 9.0 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 EKX30810.1 - 3.5e-18 65.4 7.1 0.00033 20.9 0.0 8.6 5 4 5 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.30 EKX30810.1 - 7.9e-16 57.7 6.3 8.7e-07 29.1 0.0 7.9 8 0 0 8 8 8 2 Ankyrin repeat Chol_subst-bind PF09129.11 EKX30810.1 - 1e-05 24.7 0.0 1.4 7.8 0.0 5.6 2 2 4 6 6 6 1 Cholesterol oxidase, substrate-binding DUF5491 PF17595.2 EKX30810.1 - 0.0003 21.0 0.0 58 4.1 0.0 6.1 6 1 1 7 7 7 0 Family of unknown function (DUF5491) MerR-DNA-bind PF09278.11 EKX30810.1 - 0.0033 17.9 6.4 19 5.9 0.1 5.4 6 0 0 6 6 6 1 MerR, DNA binding DHFR_2 PF06442.11 EKX30810.1 - 1.2 9.0 4.9 35 4.3 0.0 4.1 5 0 0 5 5 5 0 R67 dihydrofolate reductase Nitr_red_alph_N PF14710.6 EKX30811.1 - 0.012 16.1 0.3 4.8 7.7 0.0 3.2 3 0 0 3 3 3 0 Respiratory nitrate reductase alpha N-terminal Keratin_2_head PF16208.5 EKX30813.1 - 0.018 15.2 25.5 0.033 14.3 25.5 1.4 1 0 0 1 1 1 0 Keratin type II head Atg8 PF02991.16 EKX30815.1 - 2.1e-15 56.8 0.0 2.5e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Ribo_biogen_C PF04034.13 EKX30817.1 - 0.15 11.8 0.1 0.59 9.9 0.0 2.1 2 1 0 2 2 2 0 Ribosome biogenesis protein, C-terminal Caskin-tail PF16632.5 EKX30819.1 - 0.083 13.3 0.6 0.13 12.7 0.6 1.3 1 0 0 1 1 1 0 C-terminal region of Caskin API5 PF05918.11 EKX30819.1 - 0.94 8.2 10.7 1.1 8.0 10.7 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Ribosomal_L27e PF01777.18 EKX30820.1 - 0.023 15.1 1.4 0.037 14.4 0.2 2.0 2 0 0 2 2 2 0 Ribosomal L27e protein family DUF2829 PF11195.8 EKX30820.1 - 0.32 11.3 0.1 0.32 11.3 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2829) Corona_NS1 PF06145.11 EKX30821.1 - 0.066 12.7 3.2 3.5 7.2 0.3 2.3 2 0 0 2 2 2 0 Coronavirus nonstructural protein NS1 Cnd2 PF05786.14 EKX30821.1 - 0.13 10.9 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 Mitofilin PF09731.9 EKX30823.1 - 0.16 10.8 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Pkinase PF00069.25 EKX30824.1 - 3.6e-44 151.1 0.0 4.8e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 EKX30824.1 - 6e-32 110.5 0.0 9.8e-32 109.8 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 EKX30824.1 - 9e-26 90.7 0.0 1.2e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX30824.1 - 0.00056 18.8 0.0 0.021 13.6 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EKX30824.1 - 0.04 13.2 0.0 0.065 12.5 0.0 1.4 1 1 0 1 1 1 0 Kinase-like RIO1 PF01163.22 EKX30824.1 - 0.087 12.4 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Ifi-6-16 PF06140.13 EKX30825.1 - 2.6e-15 56.1 40.0 2.6e-15 56.1 40.0 1.9 1 1 1 2 2 2 1 Interferon-induced 6-16 family CD20 PF04103.15 EKX30825.1 - 0.019 15.1 4.6 0.026 14.6 4.6 1.2 1 0 0 1 1 1 0 CD20-like family DUF4889 PF16230.5 EKX30825.1 - 0.16 12.2 0.1 0.27 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4889) FCSD-flav_bind PF09242.11 EKX30826.1 - 0.0062 16.9 0.0 0.024 15.0 0.0 1.9 2 0 0 2 2 2 1 Flavocytochrome c sulphide dehydrogenase, flavin-binding DUF374 PF04028.13 EKX30827.1 - 0.031 13.8 0.0 0.066 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF374) Collagen PF01391.18 EKX30828.1 - 2.9e-19 68.6 54.1 6.5e-11 41.8 21.2 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) SPRY PF00622.28 EKX30829.1 - 1.3e-10 41.4 0.9 3.9e-09 36.7 0.9 2.2 1 1 0 1 1 1 1 SPRY domain TIG PF01833.24 EKX30830.1 - 8.6e-52 173.2 32.4 1.1e-08 35.0 0.8 10.8 11 0 0 11 11 11 10 IPT/TIG domain TIG_plexin PF17960.1 EKX30830.1 - 4.5e-08 33.0 0.0 0.061 13.3 0.0 6.2 6 0 0 6 6 6 2 TIG domain Anth_Ig PF05587.13 EKX30830.1 - 5.2e-05 23.5 4.9 0.023 15.0 0.0 5.5 5 1 0 5 5 5 1 Anthrax receptor extracellular domain C_LFY_FLO PF17538.2 EKX30832.1 - 0.046 13.2 0.1 0.048 13.1 0.1 1.0 1 0 0 1 1 1 0 DNA Binding Domain (C-terminal) Leafy/Floricaula IBR PF01485.21 EKX30833.1 - 1.1e-08 35.2 10.8 1.1e-08 35.2 10.8 1.9 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain OrfB_Zn_ribbon PF07282.11 EKX30833.1 - 0.21 11.5 7.7 0.09 12.7 4.6 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Phage_holin_2_4 PF16082.5 EKX30836.1 - 0.034 13.9 0.2 0.042 13.6 0.2 1.1 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF4059 PF13268.6 EKX30836.1 - 0.049 14.0 0.1 0.062 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4059) FeoB_associated PF12669.7 EKX30836.1 - 0.062 13.7 0.1 0.083 13.3 0.1 1.1 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF4307 PF14155.6 EKX30836.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) Phage_holin_T PF11031.8 EKX30836.1 - 0.11 12.0 0.0 0.12 11.8 0.0 1.0 1 0 0 1 1 1 0 Bacteriophage T holin UL45 PF05473.12 EKX30837.1 - 0.045 13.4 0.0 0.087 12.4 0.0 1.5 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Zip PF02535.22 EKX30837.1 - 1.3 8.2 3.4 2.4 7.3 3.4 1.7 1 1 0 1 1 1 0 ZIP Zinc transporter DnaJ PF00226.31 EKX30838.1 - 1.5e-19 69.8 0.2 2.4e-19 69.2 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain GlutR_dimer PF00745.20 EKX30839.1 - 0.0028 18.1 0.6 0.27 11.7 0.6 2.7 1 1 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain Cornifin PF02389.15 EKX30839.1 - 0.01 16.0 0.2 0.011 16.0 0.2 1.1 1 0 0 1 1 1 0 Cornifin (SPRR) family Cys_rich_FGFR PF00839.17 EKX30839.1 - 0.05 13.8 19.6 1.8e+04 -7.6 19.6 4.8 1 1 0 1 1 1 0 Cysteine rich repeat Ank_2 PF12796.7 EKX30841.1 - 2.2e-15 57.0 0.4 0.00031 21.3 0.0 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX30841.1 - 8e-11 42.0 4.9 0.54 10.6 0.1 6.5 6 1 2 8 8 8 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX30841.1 - 7.4e-09 35.1 11.6 0.27 11.9 0.0 8.6 9 0 0 9 9 9 2 Ankyrin repeat Ank_4 PF13637.6 EKX30841.1 - 3.3e-07 30.7 6.8 1.3 9.7 0.0 6.5 3 3 5 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 EKX30841.1 - 6.1e-07 29.6 14.8 8.2 7.1 0.0 8.1 9 0 0 9 9 9 4 Ankyrin repeat HTH_38 PF13936.6 EKX30842.1 - 3.4e-05 23.5 0.7 6.6e-05 22.6 0.7 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 EKX30842.1 - 0.00094 18.9 0.1 0.0019 17.9 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 EKX30842.1 - 0.0012 18.9 1.7 0.0013 18.8 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain CENP-B_N PF04218.13 EKX30842.1 - 0.0018 17.8 0.2 0.0038 16.8 0.2 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain Sigma70_r4 PF04545.16 EKX30842.1 - 0.0031 17.0 0.2 0.0064 16.0 0.2 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_37 PF13744.6 EKX30842.1 - 0.026 14.4 0.1 0.05 13.6 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 EKX30842.1 - 0.074 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 MarR family HTH_38 PF13936.6 EKX30843.1 - 2e-05 24.2 0.7 4.4e-05 23.2 0.7 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 EKX30843.1 - 0.00038 20.5 0.7 0.00088 19.4 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 EKX30843.1 - 0.00057 19.6 0.1 0.0013 18.5 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain CENP-B_N PF04218.13 EKX30843.1 - 0.0013 18.3 0.2 0.0025 17.4 0.2 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain Sigma70_r4 PF04545.16 EKX30843.1 - 0.0023 17.4 0.2 0.0043 16.5 0.2 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_37 PF13744.6 EKX30843.1 - 0.017 15.1 0.1 0.029 14.3 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 EKX30843.1 - 0.037 13.9 0.1 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 MarR family PAP_assoc PF03828.19 EKX30844.1 - 6.9e-10 39.0 0.0 9.5e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Cid1 family poly A polymerase tRNA_NucTransf2 PF09249.11 EKX30844.1 - 0.0078 16.5 0.0 0.0092 16.2 0.0 1.2 1 0 0 1 1 1 1 tRNA nucleotidyltransferase, second domain Nrap_D2 PF17403.2 EKX30845.1 - 0.096 12.4 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Phosphoprotein PF00922.17 EKX30845.1 - 0.19 11.3 0.0 0.21 11.1 0.0 1.1 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein HTH_ParB PF17762.1 EKX30847.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 HTH domain found in ParB protein Ephrin_rec_like PF07699.13 EKX30850.1 - 4.2e-89 292.1 255.0 1.8e-08 34.0 4.9 22.4 18 4 4 22 22 22 17 Putative ephrin-receptor like DUF2688 PF10892.8 EKX30850.1 - 0.098 12.1 5.7 40 3.8 0.1 4.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2688) SHIPPO-rpt PF07004.12 EKX30850.1 - 6.4 7.9 51.0 14 6.8 3.1 9.6 8 0 0 8 8 8 0 Sperm-tail PG-rich repeat RWP-RK PF02042.15 EKX30851.1 - 5.6e-16 58.3 0.1 7.9e-16 57.8 0.1 1.2 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX30851.1 - 0.0014 18.4 0.1 0.015 15.1 0.0 2.2 1 1 1 2 2 2 1 Bacterial regulatory protein, Fis family CAC1F_C PF16885.5 EKX30851.1 - 0.017 14.8 2.6 0.023 14.4 2.6 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term HTH_17 PF12728.7 EKX30851.1 - 0.094 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4632 PF15451.6 EKX30851.1 - 0.33 11.0 4.7 1.1 9.4 4.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Nuc_sug_transp PF04142.15 EKX30854.1 - 1.1e-19 70.8 12.7 2.1e-19 69.9 12.7 1.4 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EKX30854.1 - 0.071 13.3 20.9 0.055 13.6 4.3 2.6 2 1 0 2 2 2 0 EamA-like transporter family Holin_BhlA PF10960.8 EKX30858.1 - 0.06 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 BhlA holin family MutS_III PF05192.18 EKX30858.1 - 0.09 13.0 1.4 0.12 12.6 1.4 1.1 1 0 0 1 1 1 0 MutS domain III Cyt_bd_oxida_II PF02322.15 EKX30859.1 - 1.1 8.5 18.7 1.3 8.3 18.7 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II Pkinase PF00069.25 EKX30861.1 - 1.2e-56 192.0 0.0 1.4e-56 191.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX30861.1 - 1e-27 97.1 0.0 1.2e-27 96.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 EKX30861.1 - 0.00027 20.1 0.0 0.00044 19.4 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 EKX30861.1 - 0.0015 18.5 0.0 0.0047 16.9 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EKX30861.1 - 0.0024 16.9 0.3 0.0028 16.7 0.3 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EKX30861.1 - 0.0068 15.8 0.1 0.0087 15.4 0.1 1.4 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EKX30861.1 - 0.11 12.1 0.1 1.3 8.6 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 FKBP_C PF00254.28 EKX30863.1 - 1.9e-13 50.5 0.0 2e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pyr_redox_2 PF07992.14 EKX30864.1 - 1.2e-59 202.0 0.1 2.3e-59 201.0 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EKX30864.1 - 8.2e-17 61.5 6.7 3.3e-15 56.4 0.2 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EKX30864.1 - 1.1e-11 44.6 0.0 1.8e-10 40.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EKX30864.1 - 1.2e-11 44.8 0.0 2.9e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Rhodanese PF00581.20 EKX30864.1 - 1.8e-09 38.1 0.0 1.4e-08 35.2 0.0 2.4 2 0 0 2 2 2 1 Rhodanese-like domain NAD_binding_8 PF13450.6 EKX30864.1 - 1.6e-07 31.5 3.4 0.005 17.1 0.1 3.0 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EKX30864.1 - 6.6e-06 25.9 6.4 0.037 13.6 1.1 4.1 3 1 1 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EKX30864.1 - 6.6e-05 21.8 1.7 1.5 7.4 0.0 4.0 3 1 1 4 4 4 2 HI0933-like protein NAD_binding_7 PF13241.6 EKX30864.1 - 0.00014 22.2 0.2 0.16 12.4 0.1 2.8 2 0 0 2 2 2 2 Putative NAD(P)-binding NAD_binding_9 PF13454.6 EKX30864.1 - 0.00082 19.4 3.4 1.9 8.4 0.4 4.1 3 1 0 4 4 4 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EKX30864.1 - 0.015 14.4 3.7 14 4.6 0.0 3.8 4 0 0 4 4 4 0 FAD binding domain TrkA_N PF02254.18 EKX30864.1 - 0.018 15.3 1.7 1.5 9.1 0.1 3.3 3 0 0 3 3 3 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 EKX30864.1 - 0.091 12.3 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HTH_micro PF17007.5 EKX30864.1 - 0.15 10.9 0.1 0.24 10.2 0.1 1.2 1 0 0 1 1 1 0 HTH-like K_oxygenase PF13434.6 EKX30864.1 - 0.16 11.0 0.1 0.81 8.8 0.0 2.1 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 EKX30864.1 - 0.8 9.0 4.5 2.6 7.3 0.3 2.9 2 1 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EKX30864.1 - 0.88 8.8 5.1 0.087 12.1 0.3 1.7 2 0 0 2 2 2 0 FAD binding domain Retro_M PF02813.14 EKX30865.1 - 0.21 12.0 0.0 0.77 10.2 0.0 1.8 2 0 0 2 2 2 0 Retroviral M domain DEAD PF00270.29 EKX30867.1 - 7.2e-36 123.6 0.0 2.5e-32 112.0 0.0 3.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX30867.1 - 1.3e-31 109.3 0.0 9.4e-31 106.4 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EKX30867.1 - 0.0018 17.5 0.0 0.0032 16.7 0.0 1.4 1 1 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 EKX30867.1 - 0.0053 16.8 0.0 0.081 12.9 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EKX30867.1 - 0.015 15.6 0.0 3.4 8.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain UTP25 PF06862.12 EKX30867.1 - 0.017 13.9 0.0 0.2 10.4 0.0 2.2 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Tap-RNA_bind PF09162.10 EKX30867.1 - 0.21 11.5 0.4 0.45 10.4 0.1 1.7 2 0 0 2 2 2 0 Tap, RNA-binding DEADboxA PF12343.8 EKX30867.1 - 0.26 11.9 13.1 0.58 10.7 13.1 1.6 1 0 0 1 1 1 0 Cold shock protein DEAD box A Ribosomal_L5e PF17144.4 EKX30868.1 - 1.1e-75 253.1 0.4 1.7e-75 252.5 0.4 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EKX30868.1 - 2.5e-26 92.4 6.3 2.5e-26 92.4 6.3 2.5 3 0 0 3 3 3 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 EKX30868.1 - 0.0021 18.4 1.5 0.0054 17.1 0.0 2.1 2 0 0 2 2 2 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast DUF1943 PF09172.11 EKX30868.1 - 10 5.3 7.1 0.6 9.3 0.7 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1943) Bac_rhodopsin PF01036.18 EKX30870.1 - 7.4e-43 146.7 23.6 9.2e-43 146.4 23.6 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Diedel PF13164.6 EKX30870.1 - 0.097 13.1 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Diedel DUF4337 PF14235.6 EKX30870.1 - 4.5 7.4 8.4 0.21 11.7 2.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) ABC1 PF03109.16 EKX30871.1 - 4e-34 117.3 0.9 1.3e-33 115.7 0.1 2.0 2 0 0 2 2 2 1 ABC1 family ERM PF00769.19 EKX30871.1 - 0.0058 16.5 11.0 0.007 16.2 11.0 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Virulence_fact PF13769.6 EKX30871.1 - 0.11 12.7 5.8 0.13 12.5 4.0 2.1 1 1 1 2 2 2 0 Virulence factor TMPIT PF07851.13 EKX30871.1 - 0.33 10.2 3.3 0.43 9.8 3.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF1266 PF06889.11 EKX30871.1 - 0.69 9.9 4.1 1.2 9.2 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) Nup54 PF13874.6 EKX30871.1 - 1.1 9.3 10.6 0.49 10.5 7.1 1.9 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Transformer PF06495.11 EKX30871.1 - 1.6 8.8 5.6 2.6 8.1 5.6 1.3 1 0 0 1 1 1 0 Fruit fly transformer protein DUF2229 PF09989.9 EKX30871.1 - 1.6 8.3 4.2 2.5 7.7 4.2 1.4 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) DivIVA PF05103.13 EKX30871.1 - 2.1 8.5 14.8 2.3 8.3 13.7 1.7 1 1 1 2 2 2 0 DivIVA protein Exonuc_VII_L PF02601.15 EKX30871.1 - 3 7.3 8.4 4 6.9 8.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit GTP_cyclohydroI PF01227.22 EKX30872.1 - 0.074 12.5 1.3 0.14 11.5 1.3 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase I RWP-RK PF02042.15 EKX30874.1 - 0.0019 18.1 0.4 0.0029 17.5 0.4 1.3 1 0 0 1 1 1 1 RWP-RK domain MAP65_ASE1 PF03999.12 EKX30875.1 - 1.4e-13 50.5 15.9 1.4e-13 50.5 15.9 1.8 1 1 1 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) Kinesin PF00225.23 EKX30876.1 - 3.5e-110 368.0 0.0 4.2e-110 367.8 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX30876.1 - 2.1e-25 89.4 0.0 3.5e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding LON_substr_bdg PF02190.16 EKX30877.1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain EF-hand_7 PF13499.6 EKX30878.1 - 8.2e-05 23.0 2.7 9.5e-05 22.8 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX30878.1 - 0.012 15.5 0.0 0.044 13.7 0.0 2.1 1 1 0 1 1 1 0 EF-hand domain SurA_N_3 PF13624.6 EKX30878.1 - 0.039 13.8 0.5 0.039 13.8 0.5 2.0 2 0 0 2 2 2 0 SurA N-terminal domain EF-hand_1 PF00036.32 EKX30878.1 - 0.04 13.5 0.0 0.15 11.6 0.0 2.0 1 0 0 1 1 1 0 EF hand C4 PF01413.19 EKX30878.1 - 0.15 12.5 0.1 0.64 10.4 0.0 2.1 2 0 0 2 2 2 0 C-terminal tandem repeated domain in type 4 procollagen MSP1_C PF07462.11 EKX30878.1 - 0.16 10.6 3.7 0.27 9.9 3.7 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Dscam_C PF12355.8 EKX30878.1 - 1.7 9.6 5.6 2 9.4 3.2 2.3 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal RMI1_N PF08585.12 EKX30880.1 - 9e-20 71.4 1.0 1.9e-19 70.3 0.2 1.6 1 1 1 2 2 2 1 RecQ mediated genome instability protein TIG PF01833.24 EKX30881.1 - 4.7e-28 97.1 7.8 4.9e-10 39.3 0.0 3.2 3 0 0 3 3 3 3 IPT/TIG domain PDZ PF00595.24 EKX30882.1 - 8.4e-06 26.1 0.3 2.1e-05 24.8 0.3 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX30882.1 - 1.8e-05 24.5 0.0 5.8e-05 22.8 0.1 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX30882.1 - 0.0031 17.8 0.7 0.0064 16.8 0.7 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX30882.1 - 0.069 13.1 0.6 0.16 12.0 0.6 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain Arm PF00514.23 EKX30882.1 - 0.36 11.0 7.9 4.1 7.6 0.0 4.8 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat THOC7 PF05615.13 EKX30885.1 - 8.8e-06 26.0 8.7 2.6e-05 24.5 8.7 1.7 1 0 0 1 1 1 1 Tho complex subunit 7 HWE_HK PF07536.14 EKX30885.1 - 0.099 13.4 0.4 0.35 11.6 0.4 1.9 1 0 0 1 1 1 0 HWE histidine kinase HeLo PF14479.6 EKX30885.1 - 0.19 11.6 5.9 0.77 9.6 3.2 2.2 2 0 0 2 2 2 0 Prion-inhibition and propagation AviRa PF11599.8 EKX30885.1 - 0.22 11.0 2.0 0.42 10.0 2.0 1.4 1 0 0 1 1 1 0 RRNA methyltransferase AviRa DUF3103 PF11301.8 EKX30885.1 - 0.41 9.4 3.3 0.33 9.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3103) DUF3450 PF11932.8 EKX30885.1 - 2.8 7.2 11.0 0.2 10.9 6.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Ax_dynein_light PF10211.9 EKX30885.1 - 3.8 7.4 13.0 6.7 6.6 13.0 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain DUF4633 PF15464.6 EKX30885.1 - 9.8 6.4 8.8 24 5.1 3.1 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4633) Trp_Tyr_perm PF03222.13 EKX30886.1 - 2.2e-05 23.7 0.3 4.1e-05 22.8 0.3 1.4 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family DUF1451 PF07295.11 EKX30888.1 - 0.0029 17.7 2.4 0.028 14.5 0.2 2.2 2 0 0 2 2 2 1 Zinc-ribbon containing domain Med8 PF10232.9 EKX30888.1 - 0.044 13.4 0.9 0.091 12.3 0.1 1.8 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 DUF883 PF05957.13 EKX30888.1 - 0.081 13.5 5.0 2.7 8.6 1.8 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Atrophin-1 PF03154.15 EKX30888.1 - 0.16 10.3 4.6 0.26 9.5 1.1 2.0 2 0 0 2 2 2 0 Atrophin-1 family PEP-utilisers_N PF05524.13 EKX30888.1 - 0.26 11.5 4.5 0.39 10.9 0.3 2.3 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF1764 PF08576.10 EKX30888.1 - 0.78 10.7 6.9 3.1 8.7 0.2 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) FKBP_N PF01346.18 EKX30888.1 - 5.7 8.0 8.5 17 6.4 0.7 2.3 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Terminase_4 PF05119.12 EKX30888.1 - 6.9 7.2 7.3 1.4 9.4 1.3 2.4 2 1 0 2 2 2 0 Phage terminase, small subunit RPN2_C PF18004.1 EKX30888.1 - 8.5 6.3 11.0 5.6 6.9 1.3 2.1 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain YtxH PF12732.7 EKX30888.1 - 9.8 6.8 10.2 0.93 10.1 3.2 2.2 2 0 0 2 2 2 0 YtxH-like protein Myb_DNA-binding PF00249.31 EKX30890.1 - 3.6e-09 36.7 0.2 0.0039 17.3 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain TEA PF01285.18 EKX30890.1 - 0.048 13.7 0.2 11 6.1 0.0 2.9 3 0 0 3 3 3 0 TEA/ATTS domain Myb_DNA-binding PF00249.31 EKX30891.1 - 1.3e-06 28.4 0.0 4.8e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EKX30892.1 - 9.8e-07 28.9 0.0 4.1e-06 26.9 0.0 2.0 1 1 0 1 1 1 1 Myb-like DNA-binding domain Ephrin_rec_like PF07699.13 EKX30893.1 - 3.4e-10 39.5 52.4 0.00027 20.7 8.1 5.7 2 2 2 5 5 5 3 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX30893.1 - 0.0021 18.4 38.5 0.15 12.5 2.7 6.5 4 2 2 6 6 6 4 TNFR/NGFR cysteine-rich region Lustrin_cystein PF14625.6 EKX30893.1 - 2.6 8.5 64.9 1.6 9.2 0.6 8.5 4 2 4 8 8 8 0 Lustrin, cysteine-rich repeated domain Ephrin_rec_like PF07699.13 EKX30894.1 - 1.3e-05 24.8 50.4 0.0062 16.3 8.9 6.6 3 3 3 6 6 6 4 Putative ephrin-receptor like AAA_28 PF13521.6 EKX30895.1 - 0.00052 20.3 0.1 0.39 10.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 EKX30895.1 - 0.00063 19.8 0.0 0.0025 17.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EKX30895.1 - 0.0035 17.9 0.0 0.0071 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EKX30895.1 - 0.011 15.6 0.0 0.036 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EKX30895.1 - 0.015 14.9 0.1 0.032 13.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EKX30895.1 - 0.02 15.3 0.0 0.039 14.3 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 EKX30895.1 - 0.025 14.3 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EKX30895.1 - 0.028 14.7 0.1 0.058 13.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EKX30895.1 - 0.035 14.5 0.0 0.073 13.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EKX30895.1 - 0.066 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 EKX30895.1 - 0.084 12.2 0.2 0.64 9.3 0.1 2.0 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 EKX30895.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EKX30895.1 - 0.13 12.4 0.3 0.33 11.1 0.1 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EKX30895.1 - 0.15 12.5 0.1 0.33 11.3 0.1 1.6 1 0 0 1 1 1 0 RNA helicase SSF PF00474.17 EKX30896.1 - 8.9e-50 169.7 2.3 1e-49 169.5 2.3 1.0 1 0 0 1 1 1 1 Sodium:solute symporter family Ribosomal_L29 PF00831.23 EKX30898.1 - 0.064 13.2 0.3 0.72 9.9 0.3 2.4 2 0 0 2 2 2 0 Ribosomal L29 protein AAA_11 PF13086.6 EKX30899.1 - 7.2e-05 22.7 0.0 7.2e-05 22.7 0.0 3.3 2 1 1 3 3 3 1 AAA domain AAA PF00004.29 EKX30899.1 - 0.0019 18.6 0.0 0.0019 18.6 0.0 2.8 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EKX30899.1 - 0.0037 16.9 2.8 0.0055 16.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EKX30899.1 - 0.011 15.5 0.0 0.011 15.5 0.0 2.8 2 1 1 3 3 3 0 AAA domain AAA_7 PF12775.7 EKX30899.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 EKX30899.1 - 0.074 13.4 0.0 0.074 13.4 0.0 2.9 2 2 1 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 EKX30899.1 - 0.16 12.2 0.0 0.16 12.2 0.0 3.0 2 1 0 2 2 2 0 AAA domain CbiA PF01656.23 EKX30899.1 - 0.64 10.1 3.2 3.4 7.8 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ndc1_Nup PF09531.10 EKX30899.1 - 0.72 8.5 8.7 0.85 8.2 8.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-C4 PF00105.18 EKX30902.1 - 0.18 12.3 1.5 0.33 11.5 1.5 1.4 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) DUF4837 PF16125.5 EKX30903.1 - 0.049 12.7 0.3 0.08 12.0 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4837) Glycos_transf_2 PF00535.26 EKX30904.1 - 1.4e-15 57.5 0.0 2e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EKX30904.1 - 6.9e-07 29.4 0.0 8.4e-07 29.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 MF_alpha_N PF05436.11 EKX30904.1 - 0.022 14.7 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Glyco_tranf_2_4 PF13704.6 EKX30904.1 - 0.028 14.9 0.0 0.037 14.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 2 Osmo_MPGsynth PF09488.10 EKX30904.1 - 0.032 12.9 0.0 2.7 6.6 0.0 2.0 2 0 0 2 2 2 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) zf-C4 PF00105.18 EKX30908.1 - 0.1 13.1 1.5 0.22 12.0 1.5 1.5 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) DUF805 PF05656.14 EKX30910.1 - 6.7 7.2 18.0 1.6e+02 2.7 18.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF805) TPR_11 PF13414.6 EKX30911.1 - 5.2e-20 70.9 0.1 2.5e-06 27.1 0.0 4.1 2 1 2 4 4 4 4 TPR repeat TPR_2 PF07719.17 EKX30911.1 - 1.9e-17 61.9 0.0 1.2e-05 25.0 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX30911.1 - 8.6e-15 53.8 0.0 2.5e-07 30.2 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX30911.1 - 1.6e-14 53.9 0.2 4.8e-09 36.4 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX30911.1 - 2.7e-14 52.1 0.0 0.0012 18.9 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX30911.1 - 2e-13 50.7 1.2 2.7e-07 31.1 0.4 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 EKX30911.1 - 2.9e-09 36.7 0.0 0.22 12.0 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX30911.1 - 1.7e-08 34.6 4.0 0.19 12.6 0.0 4.0 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX30911.1 - 8.7e-08 31.8 1.0 0.0056 16.5 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX30911.1 - 2.2e-07 30.9 1.3 0.0022 18.1 0.1 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX30911.1 - 1.6e-06 27.7 0.0 1.2 9.3 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX30911.1 - 4.8e-06 26.9 0.0 0.023 15.3 0.0 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX30911.1 - 2.9e-05 24.5 0.3 0.11 13.0 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat ANAPC5 PF12862.7 EKX30911.1 - 0.00053 20.0 0.1 0.028 14.5 0.1 2.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 5 BTAD PF03704.17 EKX30911.1 - 0.00058 20.3 0.4 0.53 10.7 0.1 2.2 1 1 1 2 2 2 2 Bacterial transcriptional activator domain Coatomer_E PF04733.14 EKX30911.1 - 0.014 14.8 0.0 0.59 9.5 0.0 2.1 2 0 0 2 2 2 0 Coatomer epsilon subunit TPR_4 PF07721.14 EKX30911.1 - 0.036 14.7 0.3 6.9 7.6 0.2 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat FAT PF02259.23 EKX30911.1 - 0.049 12.9 0.0 3.4 6.8 0.0 2.2 1 1 1 2 2 2 0 FAT domain Glyco_transf_5 PF08323.11 EKX30912.1 - 1.7e-33 116.4 0.0 2.7e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain DUF848 PF05852.11 EKX30912.1 - 0.015 15.4 0.2 0.023 14.8 0.2 1.2 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Myb_DNA-binding PF00249.31 EKX30913.1 - 4.2e-10 39.7 0.1 1.2e-09 38.2 0.1 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain RWP-RK PF02042.15 EKX30916.1 - 4.4e-18 65.0 0.2 7.6e-18 64.2 0.2 1.4 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX30917.1 - 2.5e-18 65.8 0.2 4e-18 65.1 0.2 1.3 1 0 0 1 1 1 1 RWP-RK domain Actin PF00022.19 EKX30918.1 - 1.1e-36 126.3 0.0 1.2e-36 126.2 0.0 1.0 1 0 0 1 1 1 1 Actin ROK PF00480.20 EKX30918.1 - 0.13 11.7 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 ROK family PAS_8 PF13188.7 EKX30919.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 PAS domain TruD PF01142.18 EKX30920.1 - 1.1e-18 67.3 0.0 1.2e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) TIG PF01833.24 EKX30921.1 - 6.9e-57 189.5 33.5 8.8e-11 41.7 0.3 11.6 11 1 0 11 11 11 11 IPT/TIG domain Anth_Ig PF05587.13 EKX30921.1 - 1.1e-09 38.5 1.1 0.026 14.8 0.0 4.6 4 1 0 4 4 4 3 Anthrax receptor extracellular domain TIG_plexin PF17960.1 EKX30921.1 - 5.9e-09 35.8 0.0 0.54 10.3 0.0 5.7 5 0 0 5 5 5 3 TIG domain CARDB PF07705.11 EKX30921.1 - 0.47 10.8 2.5 7.3 6.9 0.3 3.3 4 0 0 4 4 4 0 CARDB BNR PF02012.20 EKX30921.1 - 2.6 8.4 8.9 1.1 9.5 0.3 4.4 3 0 0 3 3 3 0 BNR/Asp-box repeat NUDIX PF00293.28 EKX30926.1 - 2.8e-10 40.3 0.2 5.5e-10 39.4 0.2 1.5 1 0 0 1 1 1 1 NUDIX domain DUF4809 PF16067.5 EKX30927.1 - 0.13 12.4 0.4 0.22 11.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4809) zf-C3HC4_3 PF13920.6 EKX30929.1 - 2.6e-15 56.0 7.0 3.3e-15 55.7 7.0 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX30929.1 - 2e-09 37.1 8.4 2.6e-09 36.8 8.4 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EKX30929.1 - 4.4e-07 30.1 6.8 6.1e-07 29.7 6.8 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EKX30929.1 - 6.9e-07 29.0 8.2 9.7e-07 28.6 8.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EKX30929.1 - 1.4e-06 28.0 8.1 2e-06 27.5 8.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX30929.1 - 0.00037 20.4 8.8 0.00051 19.9 8.8 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 EKX30929.1 - 0.00097 18.9 5.8 0.0018 18.0 5.8 1.5 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF1644 PF07800.12 EKX30929.1 - 0.012 15.7 7.2 0.059 13.4 2.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) Rad50_zn_hook PF04423.14 EKX30929.1 - 0.021 14.7 0.2 0.042 13.7 0.2 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-P11 PF03854.14 EKX30929.1 - 0.04 13.6 2.4 0.068 12.8 2.4 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_11 PF17123.5 EKX30929.1 - 0.061 13.1 0.8 0.061 13.1 0.8 2.5 2 1 1 3 3 3 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 EKX30929.1 - 0.068 13.3 5.3 0.22 11.7 5.5 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING ProRS-C_1 PF09180.11 EKX30929.1 - 0.079 13.2 1.8 0.85 9.9 0.0 2.1 2 0 0 2 2 2 0 Prolyl-tRNA synthetase, C-terminal zf-RING_UBOX PF13445.6 EKX30929.1 - 0.21 11.6 6.1 0.43 10.7 2.0 2.5 2 0 0 2 2 2 0 RING-type zinc-finger DZR PF12773.7 EKX30929.1 - 0.28 11.2 7.2 0.25 11.4 1.6 2.1 1 1 1 2 2 2 0 Double zinc ribbon zf-C4H2 PF10146.9 EKX30929.1 - 3 8.1 6.2 3.4 7.9 6.2 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein MAP65_ASE1 PF03999.12 EKX30930.1 - 2.5e-13 49.6 5.6 2.5e-13 49.6 5.6 3.1 2 1 0 3 3 3 1 Microtubule associated protein (MAP65/ASE1 family) Syntaxin_2 PF14523.6 EKX30930.1 - 0.88 10.0 7.6 0.18 12.2 1.0 3.2 3 0 0 3 3 3 0 Syntaxin-like protein CART PF06373.11 EKX30930.1 - 2 8.7 5.9 2.6 8.3 0.7 3.2 3 0 0 3 3 3 0 Cocaine and amphetamine regulated transcript protein (CART) SHIPPO-rpt PF07004.12 EKX30931.1 - 6.9e-09 36.2 21.8 2 9.5 0.1 11.1 13 0 0 13 13 13 4 Sperm-tail PG-rich repeat PDZ PF00595.24 EKX30931.1 - 0.00048 20.4 0.1 0.0011 19.3 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX30931.1 - 0.0027 17.5 0.0 0.0069 16.2 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Glyco_tran_WbsX PF14307.6 EKX30932.1 - 3.7e-10 39.8 0.0 2.6e-09 37.0 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase WbsX Glyco_hydro_99 PF16317.5 EKX30932.1 - 3.2e-09 36.4 10.7 0.0017 17.5 0.0 4.7 4 1 1 5 5 5 4 Glycosyl hydrolase family 99 KASH_CCD PF14662.6 EKX30934.1 - 0.22 11.4 28.5 0.028 14.2 12.6 2.7 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH ZapB PF06005.12 EKX30934.1 - 0.61 10.6 28.2 2.4 8.6 8.2 3.6 1 1 1 2 2 2 0 Cell division protein ZapB NYD-SP28_assoc PF14775.6 EKX30934.1 - 3.7 7.7 12.1 27 5.0 1.0 3.8 2 1 1 3 3 3 0 Sperm tail C-terminal domain APC_N_CC PF16689.5 EKX30934.1 - 4.2 7.5 15.0 33 4.6 0.6 4.6 2 2 2 4 4 4 0 Coiled-coil N-terminus of APC, dimerisation domain TSC22 PF01166.18 EKX30934.1 - 4.7 7.6 8.3 29 5.1 0.6 3.8 2 1 1 3 3 3 0 TSC-22/dip/bun family DUF724 PF05266.14 EKX30934.1 - 5.3 6.8 19.3 10 5.9 2.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) bZIP_1 PF00170.21 EKX30934.1 - 6.2 7.0 21.1 0.26 11.4 2.5 3.8 3 1 1 4 4 4 0 bZIP transcription factor Sporozoite_P67 PF05642.11 EKX30938.1 - 0.062 11.4 3.3 0.074 11.1 3.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Maf PF02545.14 EKX30938.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.4 2 0 0 2 2 2 0 Maf-like protein Nop14 PF04147.12 EKX30938.1 - 3 6.0 11.7 3.6 5.7 11.7 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 EKX30938.1 - 7.5 5.8 10.2 9.9 5.4 10.2 1.2 1 0 0 1 1 1 0 NOA36 protein DUF4398 PF14346.6 EKX30940.1 - 1.5 9.5 5.9 0.14 12.8 1.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) Peptidase_U57 PF05582.12 EKX30941.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 YabG peptidase U57 DUF3188 PF11384.8 EKX30941.1 - 1.8 8.3 5.2 1.9 8.3 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) 2TM PF13239.6 EKX30941.1 - 2.5 8.5 5.4 1.5 9.1 3.6 1.5 1 1 1 2 2 2 0 2TM domain SPX PF03105.19 EKX30942.1 - 1.6e-10 41.5 4.5 1.5e-05 25.1 0.4 2.1 1 1 1 2 2 2 2 SPX domain RLL PF10036.9 EKX30943.1 - 0.0023 17.8 4.0 0.0023 17.8 4.0 2.4 2 0 0 2 2 2 1 RNA transcription, translation and transport factor protein CNDH2_C PF16858.5 EKX30943.1 - 2.1 8.2 26.4 2 8.2 8.1 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term FAM60A PF15396.6 EKX30943.1 - 7 6.6 18.4 9 6.2 5.1 2.4 2 0 0 2 2 2 0 Protein Family FAM60A Aminotran_5 PF00266.19 EKX30944.1 - 3.2e-26 92.2 0.0 4e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EKX30944.1 - 3.9e-08 32.9 0.0 5.2e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EKX30944.1 - 4.5e-08 32.8 0.0 6.1e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EKX30944.1 - 0.002 16.7 0.0 0.003 16.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme TMP-TENI PF02581.17 EKX30944.1 - 0.038 13.3 0.0 0.062 12.6 0.0 1.2 1 0 0 1 1 1 0 Thiamine monophosphate synthase DUF572 PF04502.13 EKX30945.1 - 0.7 9.5 6.0 0.67 9.5 6.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) SPX PF03105.19 EKX30945.1 - 7.7 6.3 16.3 8.9 6.1 16.3 1.2 1 0 0 1 1 1 0 SPX domain Hormone_5 PF00184.17 EKX30946.1 - 0.062 14.1 10.9 53 4.7 10.9 2.5 1 1 0 1 1 1 0 Neurohypophysial hormones, C-terminal Domain Keratin_B2_2 PF13885.6 EKX30946.1 - 1.9 8.5 17.2 20 5.2 7.8 2.3 1 1 1 2 2 2 0 Keratin, high sulfur B2 protein Defensin_1 PF00323.19 EKX30946.1 - 6.6 7.4 9.1 83 3.9 0.6 3.5 1 1 6 7 7 7 0 Mammalian defensin Beta_helix PF13229.6 EKX30947.1 - 2.4e-11 43.8 0.4 4.8e-11 42.8 0.4 1.5 1 0 0 1 1 1 1 Right handed beta helix region DUF4957 PF16318.5 EKX30947.1 - 4e-05 23.6 3.0 0.055 13.4 0.8 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4957) NosD PF05048.13 EKX30947.1 - 0.00043 19.6 0.5 0.0018 17.6 0.3 1.7 1 1 1 2 2 2 1 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.7 EKX30947.1 - 0.003 17.5 0.2 0.01 15.7 0.1 1.8 2 0 0 2 2 2 1 Pectate lyase superfamily protein DUF1565 PF07602.11 EKX30947.1 - 0.076 12.3 0.1 0.16 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) HEPN_Swt1 PF18731.1 EKX30947.1 - 0.083 13.2 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 Swt1-like HEPN Nop14 PF04147.12 EKX30948.1 - 0.06 11.6 29.2 0.068 11.4 29.2 1.0 1 0 0 1 1 1 0 Nop14-like family BAF1_ABF1 PF04684.13 EKX30948.1 - 0.079 12.0 10.7 0.087 11.9 10.7 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SDA1 PF05285.12 EKX30948.1 - 1.5 8.2 32.5 1.6 8.1 32.5 1.1 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.12 EKX30948.1 - 1.7 7.0 21.2 1.9 6.9 21.2 1.1 1 0 0 1 1 1 0 Mpp10 protein Chloroa_b-bind PF00504.21 EKX30949.1 - 1.7e-30 106.7 0.0 2.5e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein EF-hand_5 PF13202.6 EKX30949.1 - 4.6e-06 25.9 0.1 1.5e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 EKX30949.1 - 4e-05 22.8 0.1 0.00046 19.5 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EKX30949.1 - 6.4e-05 22.6 0.0 0.00016 21.3 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 EKX30949.1 - 0.00053 20.4 0.1 0.0014 19.1 0.1 1.7 1 1 0 1 1 1 1 EF-hand domain pair DctP PF03480.13 EKX30949.1 - 0.059 12.7 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 EF-hand_8 PF13833.6 EKX30949.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair Chloroa_b-bind PF00504.21 EKX30950.1 - 2.1e-30 106.4 0.0 3e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein EF-hand_1 PF00036.32 EKX30950.1 - 1.3e-11 43.1 0.2 8.1e-05 21.9 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EKX30950.1 - 6.9e-10 38.0 0.1 1.2e-05 24.6 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX30950.1 - 8e-10 39.0 0.0 1.6e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX30950.1 - 9.5e-09 34.5 0.2 2.3e-05 24.0 0.0 2.5 1 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EKX30950.1 - 4.2e-08 32.9 0.3 4.5e-06 26.4 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair DctP PF03480.13 EKX30950.1 - 0.062 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 Redoxin PF08534.10 EKX30951.1 - 4.3e-19 68.7 0.0 4.8e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EKX30951.1 - 1.1e-06 28.6 0.0 1.3e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Pkinase PF00069.25 EKX30953.1 - 2.3e-40 138.6 0.0 3.2e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX30953.1 - 2.9e-36 125.1 0.0 2.9e-21 75.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX30953.1 - 0.00042 19.2 0.0 0.00061 18.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX30953.1 - 0.0012 18.8 0.1 0.0024 17.9 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family RWP-RK PF02042.15 EKX30955.1 - 2.4e-13 49.8 0.2 3.6e-13 49.3 0.2 1.2 1 0 0 1 1 1 1 RWP-RK domain HTH_31 PF13560.6 EKX30955.1 - 0.051 13.9 0.3 2.2 8.7 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_8 PF02954.19 EKX30955.1 - 0.14 12.0 0.4 1.8 8.4 0.0 2.3 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family Metallophos PF00149.28 EKX30956.1 - 7e-07 29.9 0.1 7.2e-07 29.9 0.1 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EKX30956.1 - 5e-05 23.6 0.0 6.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain HSBP1 PF06825.12 EKX30957.1 - 1.1e-10 41.2 10.3 0.037 13.9 0.1 5.9 1 1 5 6 6 6 4 Heat shock factor binding protein 1 ABC_tran_CTD PF16326.5 EKX30957.1 - 1.3e-09 38.2 0.0 0.013 15.7 0.0 4.1 3 1 1 4 4 4 2 ABC transporter C-terminal domain SKA2 PF16740.5 EKX30957.1 - 1e-05 25.3 10.7 0.0021 17.9 1.9 3.4 1 1 2 3 3 3 2 Spindle and kinetochore-associated protein 2 CdvA PF18822.1 EKX30957.1 - 1.2e-05 25.1 5.7 0.6 9.9 0.1 4.1 1 1 3 4 4 4 3 CdvA-like coiled-coil domain CLZ PF16526.5 EKX30957.1 - 1.8e-05 25.0 6.6 2.2 8.7 0.1 5.2 2 1 4 6 6 5 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Prefoldin_2 PF01920.20 EKX30957.1 - 1.9e-05 24.6 7.1 4.1 7.4 0.1 5.1 1 1 4 5 5 5 0 Prefoldin subunit Osmo_CC PF08946.10 EKX30957.1 - 0.00022 21.4 2.2 45 4.4 0.0 6.1 2 1 4 6 6 6 0 Osmosensory transporter coiled coil Baculo_PEP_C PF04513.12 EKX30957.1 - 0.00061 19.9 7.4 0.074 13.1 0.3 3.0 1 1 2 3 3 3 3 Baculovirus polyhedron envelope protein, PEP, C terminus DUF16 PF01519.16 EKX30957.1 - 0.0011 19.5 17.5 0.29 11.6 3.8 3.9 1 1 2 3 3 3 2 Protein of unknown function DUF16 GPS2_interact PF15784.5 EKX30957.1 - 0.0012 19.3 7.5 2.1 8.8 0.2 4.4 1 1 4 5 5 5 1 G-protein pathway suppressor 2-interacting domain Golgin_A5 PF09787.9 EKX30957.1 - 0.0024 17.4 19.3 0.045 13.2 12.1 2.2 1 1 1 2 2 2 2 Golgin subfamily A member 5 FlaC_arch PF05377.11 EKX30957.1 - 0.0032 17.8 14.4 20 5.7 0.1 6.1 1 1 2 5 5 5 0 Flagella accessory protein C (FlaC) DUF3584 PF12128.8 EKX30957.1 - 0.015 12.8 12.3 0.029 11.9 12.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ZapB PF06005.12 EKX30957.1 - 0.021 15.2 6.4 13 6.3 0.2 4.2 1 1 3 4 4 4 0 Cell division protein ZapB LXG PF04740.12 EKX30957.1 - 0.029 14.1 13.4 2.5 7.7 0.9 4.5 1 1 3 4 4 4 0 LXG domain of WXG superfamily Spectrin PF00435.21 EKX30957.1 - 0.049 14.1 5.8 13 6.3 0.2 3.6 1 1 3 4 4 4 0 Spectrin repeat DUF2183 PF09949.9 EKX30957.1 - 0.059 13.7 0.0 0.22 11.9 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) DUF1366 PF07104.11 EKX30957.1 - 0.096 12.4 5.8 64 3.3 0.5 4.5 1 1 3 4 4 4 0 Protein of unknown function (DUF1366) Vps53_N PF04100.12 EKX30957.1 - 0.1 11.5 14.7 0.48 9.3 2.8 3.1 1 1 2 3 3 3 0 Vps53-like, N-terminal YabA PF06156.13 EKX30957.1 - 0.11 13.2 9.7 51 4.6 0.6 5.3 1 1 4 5 5 4 0 Initiation control protein YabA DUF724 PF05266.14 EKX30957.1 - 0.11 12.3 16.0 1.1 9.0 1.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF724) HMMR_N PF15905.5 EKX30957.1 - 0.11 11.9 14.2 0.032 13.7 5.5 2.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal SLATT_6 PF18169.1 EKX30957.1 - 0.15 11.6 10.6 5.5 6.6 0.5 4.3 1 1 5 6 6 6 0 SMODS and SLOG-associating 2TM effector domain 6 COG2 PF06148.11 EKX30957.1 - 0.19 11.8 13.7 0.94 9.6 1.3 3.6 1 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4795 PF16043.5 EKX30957.1 - 0.21 11.2 11.3 0.55 9.8 6.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Fibin PF15819.5 EKX30957.1 - 0.22 11.3 14.3 2.4 7.9 0.3 4.3 1 1 2 4 4 4 0 Fin bud initiation factor homologue Allexi_40kDa PF05549.11 EKX30957.1 - 0.24 10.9 11.8 1.4 8.3 1.3 2.3 1 1 1 2 2 2 0 Allexivirus 40kDa protein UPF0184 PF03670.13 EKX30957.1 - 0.25 11.7 14.6 55 4.2 0.3 5.4 1 1 5 6 6 6 0 Uncharacterised protein family (UPF0184) PMC2NT PF08066.12 EKX30957.1 - 0.26 12.0 19.2 0.54 11.0 2.6 4.2 2 1 3 5 5 5 0 PMC2NT (NUC016) domain Snapin_Pallidin PF14712.6 EKX30957.1 - 0.31 11.5 9.4 5 7.6 1.0 3.8 2 1 0 3 3 3 0 Snapin/Pallidin Phage_GPO PF05929.11 EKX30957.1 - 0.37 10.4 14.2 1.6 8.3 3.2 2.8 1 1 2 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase AATF-Che1 PF13339.6 EKX30957.1 - 0.53 11.0 12.2 3.4e+03 -1.4 12.2 3.6 1 1 0 1 1 0 0 Apoptosis antagonizing transcription factor SKA1 PF07160.12 EKX30957.1 - 0.62 9.9 16.2 0.51 10.2 2.8 3.6 2 1 2 4 4 4 0 Spindle and kinetochore-associated protein 1 ADIP PF11559.8 EKX30957.1 - 0.82 9.7 14.7 5.8 7.0 2.0 3.7 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF5595 PF18077.1 EKX30957.1 - 0.89 9.7 7.4 33 4.6 0.0 4.7 1 1 4 5 5 5 0 Domain of unknown function (DUF5595) DUF4200 PF13863.6 EKX30957.1 - 0.94 9.9 8.6 6.5 7.2 1.4 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF948 PF06103.11 EKX30957.1 - 1 9.7 7.8 67 3.8 0.3 3.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Exonuc_VII_L PF02601.15 EKX30957.1 - 1.1 8.8 11.5 24 4.4 11.5 2.2 1 1 0 1 1 1 0 Exonuclease VII, large subunit GAS PF13851.6 EKX30957.1 - 1.1 8.5 14.3 3.1 7.1 4.6 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ChlamPMP_M PF07548.11 EKX30957.1 - 1.2 9.1 3.0 18 5.3 1.5 2.7 1 1 1 2 2 2 0 Chlamydia polymorphic membrane protein middle domain Spc7 PF08317.11 EKX30957.1 - 1.2 7.9 13.5 2.6 6.8 4.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein TMPIT PF07851.13 EKX30957.1 - 1.8 7.7 14.8 5 6.3 2.4 2.9 2 1 1 3 3 3 0 TMPIT-like protein DUF2408 PF10303.9 EKX30957.1 - 1.8 9.1 11.3 2.2e+02 2.4 11.2 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Apolipoprotein PF01442.18 EKX30957.1 - 2.2 8.1 9.8 27 4.6 9.0 2.6 2 1 0 2 2 1 0 Apolipoprotein A1/A4/E domain TgMIC1 PF11476.8 EKX30957.1 - 2.6 7.8 8.6 84 2.9 0.1 4.4 1 1 4 5 5 5 0 Toxoplasma gondii micronemal protein 1 TgMIC1 DUF1993 PF09351.10 EKX30957.1 - 3.2 7.9 5.7 40 4.3 0.1 3.3 1 1 4 5 5 5 0 Domain of unknown function (DUF1993) DUF4140 PF13600.6 EKX30957.1 - 4.1 7.9 8.7 65 4.0 0.6 3.6 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Uso1_p115_C PF04871.13 EKX30957.1 - 4.8 7.6 8.6 33 4.9 2.5 2.9 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region TPR_MLP1_2 PF07926.12 EKX30957.1 - 5.9 7.0 13.8 17 5.5 0.8 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2205 PF10224.9 EKX30957.1 - 6.4 6.9 17.2 53 3.9 0.6 5.2 1 1 4 5 5 5 0 Short coiled-coil protein TRPM_tetra PF16519.5 EKX30957.1 - 8.8 6.5 16.7 48 4.1 0.2 5.5 2 1 3 5 5 5 0 Tetramerisation domain of TRPM Fib_alpha PF08702.10 EKX30957.1 - 9.4 6.4 16.9 11 6.2 3.6 3.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.19 EKX30957.1 - 9.8 4.0 14.3 24 2.7 13.4 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family HSBP1 PF06825.12 EKX30958.1 - 0.0039 17.0 0.1 0.016 15.0 0.1 2.0 1 1 1 2 2 2 1 Heat shock factor binding protein 1 CLZ PF16526.5 EKX30958.1 - 0.15 12.4 0.1 0.74 10.2 0.1 1.9 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PMC2NT PF08066.12 EKX30958.1 - 0.2 12.4 1.4 0.98 10.2 0.5 2.2 2 0 0 2 2 2 0 PMC2NT (NUC016) domain Fim-adh_lectin PF09222.10 EKX30959.1 - 0.007 15.9 1.0 0.008 15.7 1.0 1.1 1 0 0 1 1 1 1 Fimbrial adhesin F17-AG, lectin domain HIP1_clath_bdg PF16515.5 EKX30962.1 - 1.4 9.6 4.9 2.5 8.8 4.9 1.4 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PseudoU_synth_2 PF00849.22 EKX30963.1 - 7.3e-11 42.4 0.1 1.3e-10 41.5 0.1 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 EKX30963.1 - 0.00044 19.9 0.4 0.0012 18.5 0.4 1.8 1 0 0 1 1 1 1 S4 domain TPM_phosphatase PF04536.14 EKX30966.1 - 3.1e-23 82.3 0.0 3.3e-22 79.0 0.0 2.4 2 1 0 2 2 2 1 TPM domain MOLO1 PF17175.4 EKX30966.1 - 1.5e-14 54.1 0.0 3.2e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 zf-RING_UBOX PF13445.6 EKX30966.1 - 0.016 15.2 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DUF3175 PF11373.8 EKX30966.1 - 0.024 14.8 0.8 0.063 13.5 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3175) TPR_21 PF09976.9 EKX30966.1 - 0.04 13.6 0.1 0.067 12.9 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain DUF5130 PF17174.4 EKX30966.1 - 0.046 13.9 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5130) DUF3290 PF11694.8 EKX30966.1 - 0.064 13.2 0.8 0.11 12.4 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Hydrolase_3 PF08282.12 EKX30967.1 - 0.0011 18.8 0.0 0.0011 18.7 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase_Tyr PF07714.17 EKX30968.1 - 8.4e-49 166.2 0.0 9.9e-49 165.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX30968.1 - 3.1e-19 69.4 0.0 4e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.6 EKX30969.1 - 1e-43 147.1 3.0 4.4e-07 30.3 0.0 7.6 4 2 5 9 9 9 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX30969.1 - 1.8e-41 140.6 5.6 2.4e-09 37.7 0.1 6.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX30969.1 - 1.1e-33 114.9 14.5 0.0043 17.3 0.0 10.9 5 4 6 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX30969.1 - 2.6e-24 82.6 3.4 0.24 12.0 0.0 11.2 11 0 0 11 11 11 5 Ankyrin repeat Ank PF00023.30 EKX30969.1 - 6.3e-13 48.5 16.5 0.95 10.0 0.0 10.6 11 0 0 11 11 11 4 Ankyrin repeat Chol_subst-bind PF09129.11 EKX30969.1 - 0.16 10.9 0.0 62 2.4 0.0 3.9 3 2 2 5 5 5 0 Cholesterol oxidase, substrate-binding Ins_beta PF03488.14 EKX30969.1 - 0.17 11.9 19.5 39 4.4 0.0 8.4 10 0 0 10 10 10 0 Nematode insulin-related peptide beta type DUF4568 PF15132.6 EKX30969.1 - 1.2 8.5 5.3 61 2.9 0.1 4.2 3 2 1 4 4 4 0 Domain of unknown function (DUF4568) FYVE PF01363.21 EKX30971.1 - 5e-15 55.4 8.0 5e-15 55.4 8.0 3.6 4 0 0 4 4 4 1 FYVE zinc finger CxC5 PF18718.1 EKX30971.1 - 0.0024 18.0 2.1 0.0065 16.5 2.1 1.7 1 0 0 1 1 1 1 CxC5 like cysteine cluster associated with KDZ transposases AIG1 PF04548.16 EKX30971.1 - 0.0049 16.2 0.0 0.0099 15.2 0.0 1.5 1 0 0 1 1 1 1 AIG1 family GBP PF02263.19 EKX30971.1 - 0.0059 15.9 0.1 0.0094 15.2 0.1 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain DUF1090 PF06476.12 EKX30975.1 - 1.9e-06 28.0 36.5 0.22 11.6 2.5 5.3 1 1 4 5 5 5 5 Protein of unknown function (DUF1090) HTH_53 PF18606.1 EKX30975.1 - 0.0012 18.5 9.9 16 5.3 0.1 5.8 1 1 5 6 6 6 4 Zap helix turn helix N-terminal domain DUF3035 PF11233.8 EKX30975.1 - 1.8 8.9 17.5 4 7.7 4.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3035) DHR10 PF18595.1 EKX30975.1 - 4.1 7.5 22.0 3.9 7.6 0.8 3.8 1 1 3 4 4 4 0 Designed helical repeat protein 10 domain PDZ_6 PF17820.1 EKX30976.1 - 0.00025 20.8 0.4 0.0019 18.0 0.1 2.4 2 0 0 2 2 2 1 PDZ domain DDHD PF02862.17 EKX30976.1 - 0.11 12.7 20.3 0.043 14.0 15.1 2.2 2 0 0 2 2 2 0 DDHD domain eIF-3_zeta PF05091.12 EKX30976.1 - 0.15 11.0 28.3 0.26 10.2 28.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AAA_11 PF13086.6 EKX30976.1 - 0.17 11.7 21.9 0.033 14.0 17.4 1.9 2 0 0 2 2 2 0 AAA domain RR_TM4-6 PF06459.12 EKX30976.1 - 0.31 10.8 26.9 0.16 11.8 22.4 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Endostatin PF06482.11 EKX30976.1 - 0.34 10.3 22.8 0.056 12.9 18.3 1.8 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin DUF913 PF06025.12 EKX30976.1 - 0.41 9.6 16.7 0.26 10.2 13.8 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF2347 PF09804.9 EKX30976.1 - 0.52 9.8 15.8 0.94 9.0 15.8 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Pex14_N PF04695.13 EKX30976.1 - 0.8 10.3 39.6 0.17 12.5 35.5 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Velvet PF11754.8 EKX30976.1 - 0.82 9.6 24.7 0.24 11.3 20.7 1.9 2 0 0 2 2 2 0 Velvet factor SID-1_RNA_chan PF13965.6 EKX30976.1 - 1.1 7.6 9.7 1.5 7.1 9.7 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 LicD PF04991.13 EKX30976.1 - 1.2 9.2 9.1 1.4 9.0 7.0 1.9 2 0 0 2 2 2 0 LicD family MDM31_MDM32 PF08118.11 EKX30976.1 - 1.9 7.0 17.9 0.72 8.5 15.3 1.5 2 0 0 2 2 2 0 Yeast mitochondrial distribution and morphology (MDM) proteins CPSF100_C PF13299.6 EKX30976.1 - 1.9 8.6 20.2 0.49 10.6 15.1 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal V_ATPase_I PF01496.19 EKX30976.1 - 2.1 6.2 24.5 0.1 10.5 19.1 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CLN3 PF02487.17 EKX30976.1 - 2.2 7.3 17.9 4 6.4 17.9 1.4 1 0 0 1 1 1 0 CLN3 protein TCP PF03634.13 EKX30976.1 - 2.3 8.8 28.5 1.4 9.5 22.5 2.3 2 0 0 2 2 2 0 TCP family transcription factor AMP-binding PF00501.28 EKX30976.1 - 2.3 6.7 6.3 3.9 6.0 6.3 1.3 1 0 0 1 1 1 0 AMP-binding enzyme CDC45 PF02724.14 EKX30976.1 - 3.6 5.8 25.4 0.22 9.8 20.2 1.5 2 0 0 2 2 2 0 CDC45-like protein Neur_chan_memb PF02932.16 EKX30976.1 - 3.7 7.5 19.5 0.83 9.7 15.1 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF2052 PF09747.9 EKX30976.1 - 3.8 7.6 31.9 4.3 7.4 26.4 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SLC12 PF03522.15 EKX30976.1 - 3.9 6.4 26.5 0.7 8.8 22.4 1.7 2 0 0 2 2 2 0 Solute carrier family 12 SpoIIP PF07454.11 EKX30976.1 - 4.4 6.7 27.2 1.2 8.6 23.2 1.9 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF2828 PF11443.8 EKX30976.1 - 6 4.8 25.7 0.4 8.7 20.6 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Nha1_C PF08619.10 EKX30976.1 - 6.1 5.9 32.8 5.4 6.1 27.8 2.1 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus BT1 PF03092.16 EKX30976.1 - 7.8 4.6 8.1 11 4.0 8.1 1.2 1 0 0 1 1 1 0 BT1 family Peptidase_S49_N PF08496.10 EKX30976.1 - 9.4 6.3 27.1 5.9 7.0 22.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal RWP-RK PF02042.15 EKX30977.1 - 5.5e-15 55.1 0.1 8.2e-15 54.5 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX30977.1 - 0.13 12.1 0.1 15 5.5 0.0 2.4 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family RWP-RK PF02042.15 EKX30979.1 - 1e-23 83.0 0.1 1.2e-23 82.8 0.1 1.0 1 0 0 1 1 1 1 RWP-RK domain Methyltrans_RNA PF04452.14 EKX30981.1 - 2.5e-23 82.6 0.0 1.5e-12 47.3 0.0 2.1 1 1 1 2 2 2 2 RNA methyltransferase EF-hand_8 PF13833.6 EKX30983.1 - 2e-09 37.1 5.4 1.3e-05 24.9 0.2 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX30983.1 - 4.5e-09 35.2 0.2 0.0046 16.4 0.3 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX30983.1 - 8.8e-09 34.6 0.8 0.0015 18.3 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EKX30983.1 - 1.5e-08 34.9 2.2 1.9e-08 34.6 0.6 2.1 2 0 0 2 2 2 1 EF-hand domain pair DUF1163 PF06651.11 EKX30983.1 - 3.3e-08 33.5 13.8 17 5.6 0.1 8.3 8 0 0 8 8 8 0 Protein of unknown function (DUF1163) EF-hand_5 PF13202.6 EKX30983.1 - 1.3e-07 30.8 1.8 0.0051 16.2 0.0 2.8 3 0 0 3 3 3 2 EF hand MurB_C PF02873.16 EKX30983.1 - 5.3e-06 26.5 4.7 1.5 8.9 0.1 7.7 8 0 0 8 8 8 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain Collagen PF01391.18 EKX30983.1 - 0.0005 19.8 14.8 0.0005 19.8 14.8 3.6 3 0 0 3 3 2 1 Collagen triple helix repeat (20 copies) SPARC_Ca_bdg PF10591.9 EKX30983.1 - 0.014 15.7 2.7 0.021 15.1 0.1 2.5 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region DUF948 PF06103.11 EKX30983.1 - 0.066 13.5 6.8 39 4.6 0.2 5.2 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Pro_dh-DNA_bdg PF14850.6 EKX30983.1 - 0.2 12.2 1.8 0.63 10.6 0.5 2.4 2 0 0 2 2 2 0 DNA-binding domain of Proline dehydrogenase DUF1978 PF09321.10 EKX30983.1 - 0.35 10.1 5.9 2.3 7.5 0.6 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1978) KELK PF15796.5 EKX30983.1 - 6.4 7.3 9.3 3 8.4 0.3 3.3 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Vert_IL3-reg_TF PF06529.11 EKX30984.1 - 0.0032 16.7 0.1 0.0069 15.6 0.1 1.5 1 0 0 1 1 1 1 Vertebrate interleukin-3 regulated transcription factor SlyX PF04102.12 EKX30984.1 - 0.0062 17.1 0.3 0.0062 17.1 0.3 2.3 2 0 0 2 2 2 1 SlyX EF-hand_1 PF00036.32 EKX30984.1 - 0.11 12.1 0.3 0.67 9.6 0.1 2.5 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.6 EKX30984.1 - 0.17 11.4 0.6 0.86 9.2 0.1 2.4 2 0 0 2 2 2 0 EF hand DUF3552 PF12072.8 EKX30984.1 - 0.19 11.2 2.1 2.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) BUD22 PF09073.10 EKX30985.1 - 5.8 6.1 67.8 6.6 6.0 67.8 1.1 1 0 0 1 1 1 0 BUD22 Ion_trans PF00520.31 EKX30986.1 - 3.6e-15 55.9 13.8 5.7e-15 55.2 13.8 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX30986.1 - 1.3e-13 50.7 4.5 1.3e-13 50.7 4.5 2.6 2 1 0 2 2 2 1 Ion channel IRK PF01007.20 EKX30986.1 - 0.47 10.3 6.9 1.3 8.8 6.9 1.7 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain Mesd PF10185.9 EKX30988.1 - 6.1e-10 39.2 0.1 6.6e-10 39.1 0.1 1.1 1 0 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor DUF261 PF03196.13 EKX30988.1 - 0.053 13.6 0.0 0.063 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF261 GST_C_2 PF13410.6 EKX30989.1 - 1e-05 25.5 0.0 1.9e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EKX30989.1 - 0.00024 21.3 0.0 0.00053 20.2 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EKX30989.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EKX30989.1 - 0.017 15.3 0.0 0.03 14.5 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF3168 PF11367.8 EKX30990.1 - 0.015 15.5 0.3 4.5 7.5 0.0 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF3168) SNF2_N PF00176.23 EKX30993.1 - 5.3e-48 163.5 4.1 6e-40 137.0 0.1 2.8 1 1 2 3 3 3 2 SNF2 family N-terminal domain SAWADEE PF16719.5 EKX30993.1 - 7.9e-11 42.1 1.7 2.7e-10 40.4 0.1 2.6 3 0 0 3 3 3 1 SAWADEE domain Chromo PF00385.24 EKX30993.1 - 1.8e-10 40.5 1.9 1.7e-09 37.4 0.1 3.2 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 EKX30993.1 - 3.5e-08 33.6 0.0 1.4e-07 31.7 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1087 PF06465.13 EKX30993.1 - 2.1e-06 27.7 2.3 5.6e-06 26.3 2.3 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) DEAD PF00270.29 EKX30993.1 - 0.00011 22.0 0.0 0.00026 20.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EKX30993.1 - 0.013 15.2 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase SnAC PF14619.6 EKX30993.1 - 1.9 9.2 6.9 0.22 12.2 1.0 2.6 2 0 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex TPR_2 PF07719.17 EKX30995.1 - 2e-16 58.7 0.0 0.0002 21.2 0.1 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX30995.1 - 1.1e-15 56.7 0.0 2e-05 24.2 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX30995.1 - 3.5e-10 39.8 22.4 0.057 14.3 0.0 7.9 7 2 2 9 9 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX30995.1 - 2.6e-09 37.2 3.0 0.031 14.6 0.2 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX30995.1 - 1.2e-08 34.5 0.0 0.011 15.9 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX30995.1 - 1.1e-07 32.2 4.8 0.027 15.0 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX30995.1 - 2e-06 27.4 0.1 0.52 10.0 0.1 5.6 5 1 1 6 6 6 2 TPR repeat TPR_16 PF13432.6 EKX30995.1 - 3.2e-06 27.7 17.0 0.23 12.1 0.3 5.4 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX30995.1 - 4.7e-06 26.3 12.2 0.2 11.6 0.1 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX30995.1 - 5.7e-05 22.9 4.9 0.44 10.7 0.1 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX30995.1 - 0.0054 17.3 0.2 28 5.6 0.2 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX30995.1 - 0.0076 16.3 0.0 9.5 6.4 0.0 3.4 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 EKX30995.1 - 0.025 14.7 11.4 0.45 10.7 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat PH PF00169.29 EKX30996.1 - 0.00098 19.6 0.0 0.0016 18.9 0.0 1.4 1 0 0 1 1 1 1 PH domain FAM176 PF14851.6 EKX30996.1 - 0.0047 16.6 0.3 0.0098 15.6 0.3 1.5 1 0 0 1 1 1 1 FAM176 family LysM PF01476.20 EKX30997.1 - 0.015 15.3 0.0 0.38 10.9 0.0 2.8 2 0 0 2 2 2 0 LysM domain Ribosomal_L3 PF00297.22 EKX30998.1 - 1.6e-18 66.8 1.5 1.2e-15 57.4 1.2 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 AA_permease_2 PF13520.6 EKX30999.1 - 1.8e-45 155.6 38.8 2.3e-45 155.2 38.8 1.1 1 0 0 1 1 1 1 Amino acid permease SLATT_1 PF18181.1 EKX30999.1 - 0.79 9.7 3.1 0.93 9.4 0.2 2.6 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 ThiF PF00899.21 EKX31001.1 - 7.1e-50 169.6 0.0 1e-49 169.1 0.0 1.1 1 0 0 1 1 1 1 ThiF family YlbD_coat PF14071.6 EKX31001.1 - 0.042 14.1 1.9 7.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Putative coat protein UDPG_MGDP_dh_N PF03721.14 EKX31001.1 - 0.088 12.4 0.0 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF3306 PF11748.8 EKX31001.1 - 0.31 11.9 2.5 0.38 11.6 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) ODV-E18 PF10717.9 EKX31002.1 - 0.077 12.9 0.7 0.15 11.9 0.7 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 LMBR1 PF04791.16 EKX31003.1 - 0.0065 15.4 0.2 0.0065 15.4 0.2 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein Phage_HK97_TLTM PF06120.11 EKX31003.1 - 0.061 12.5 2.9 0.076 12.2 2.9 1.1 1 0 0 1 1 1 0 Tail length tape measure protein DUF2390 PF09523.10 EKX31003.1 - 2.7 8.4 8.1 0.21 11.9 0.5 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2390) Rho_N PF07498.12 EKX31005.1 - 0.084 12.8 0.1 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain GlutR_dimer PF00745.20 EKX31006.1 - 0.0028 18.1 0.6 0.27 11.7 0.6 2.7 1 1 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain Cornifin PF02389.15 EKX31006.1 - 0.01 16.0 0.2 0.011 16.0 0.2 1.1 1 0 0 1 1 1 0 Cornifin (SPRR) family Cys_rich_FGFR PF00839.17 EKX31006.1 - 0.05 13.8 19.6 1.8e+04 -7.6 19.6 4.8 1 1 0 1 1 1 0 Cysteine rich repeat Ank_4 PF13637.6 EKX31007.1 - 1e-13 51.5 0.0 3.1e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX31007.1 - 2.7e-12 47.1 0.0 4e-07 30.5 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX31007.1 - 4.1e-09 36.5 0.4 0.28 11.5 0.0 3.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EKX31007.1 - 3.7e-06 27.1 0.2 0.22 12.1 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EKX31007.1 - 9.5e-06 25.6 0.0 1.4 9.7 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat WD40 PF00400.32 EKX31009.1 - 1.4e-17 63.7 9.0 0.00079 20.2 0.0 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX31009.1 - 7.8e-07 29.3 0.1 0.78 10.1 0.0 3.1 1 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EKX31009.1 - 0.033 14.1 0.0 0.13 12.1 0.0 1.8 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF5122 PF17164.4 EKX31009.1 - 0.051 13.9 0.1 0.2 12.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5122) beta-propeller PD40 PF07676.12 EKX31009.1 - 0.075 13.0 0.2 0.32 11.0 0.2 2.1 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Prefoldin PF02996.17 EKX31010.1 - 3e-31 107.8 3.7 3.6e-30 104.3 0.4 2.1 1 1 1 2 2 2 2 Prefoldin subunit Prefoldin_2 PF01920.20 EKX31010.1 - 0.00018 21.4 2.7 0.33 10.9 0.8 2.6 2 1 1 3 3 3 3 Prefoldin subunit DUF148 PF02520.17 EKX31010.1 - 0.00028 20.9 3.1 0.0003 20.8 0.7 2.1 3 0 0 3 3 3 1 Domain of unknown function DUF148 DUF4201 PF13870.6 EKX31010.1 - 0.0061 16.3 4.7 0.66 9.7 2.4 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) Mod_r PF07200.13 EKX31010.1 - 0.0098 16.0 2.1 2.9 8.0 0.1 2.3 2 0 0 2 2 2 2 Modifier of rudimentary (Mod(r)) protein DUF573 PF04504.14 EKX31010.1 - 0.073 13.7 0.4 0.16 12.6 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF573 COG2 PF06148.11 EKX31010.1 - 0.15 12.2 1.3 10 6.2 0.2 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin-6_N PF09177.11 EKX31010.1 - 0.16 12.5 2.4 1.9 9.1 0.3 2.2 1 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 EKX31010.1 - 0.27 11.3 1.2 2.9 7.9 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Exo_endo_phos PF03372.23 EKX31012.1 - 2.3e-25 89.5 0.2 4.5e-25 88.5 0.2 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SCAB-Ig PF16709.5 EKX31012.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Ig domain of plant-specific actin-binding protein Glyoxalase PF00903.25 EKX31013.1 - 1.3e-08 35.1 0.0 1.6e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EKX31013.1 - 1.4e-06 28.5 0.0 2.5e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EKX31013.1 - 0.0057 16.8 0.0 0.15 12.2 0.0 2.1 1 1 1 2 2 2 1 Glyoxalase-like domain Acetyltransf_10 PF13673.7 EKX31013.1 - 0.022 14.7 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Arm PF00514.23 EKX31014.1 - 1.7e-11 43.7 0.0 0.01 15.9 0.0 4.9 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat Mpp10 PF04006.12 EKX31014.1 - 2e-05 23.2 8.2 3e-05 22.7 8.2 1.1 1 0 0 1 1 1 1 Mpp10 protein DUF2457 PF10446.9 EKX31014.1 - 0.004 16.4 23.3 0.0063 15.7 23.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) TFB6 PF17110.5 EKX31014.1 - 0.0084 15.9 5.6 0.023 14.4 5.6 1.8 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH Sigma70_ner PF04546.13 EKX31014.1 - 0.013 15.4 13.6 0.038 13.9 13.6 1.8 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF4471 PF14740.6 EKX31014.1 - 0.061 12.5 1.0 8 5.6 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) Cwf_Cwc_15 PF04889.12 EKX31014.1 - 0.12 12.1 17.5 0.25 11.1 17.5 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RPN2_C PF18004.1 EKX31014.1 - 0.13 12.2 8.8 0.25 11.3 8.8 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RR_TM4-6 PF06459.12 EKX31014.1 - 0.19 11.5 6.5 0.3 10.9 6.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 UNC45-central PF11701.8 EKX31014.1 - 0.31 11.0 2.9 17 5.3 0.0 3.8 4 0 0 4 4 4 0 Myosin-binding striated muscle assembly central SDA1 PF05285.12 EKX31014.1 - 0.45 9.9 23.4 0.71 9.2 23.4 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EKX31014.1 - 0.55 8.4 27.9 0.83 7.8 27.9 1.1 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 EKX31014.1 - 0.56 9.5 23.0 2.8 7.3 22.7 2.1 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT TFIIA PF03153.13 EKX31014.1 - 0.73 9.8 17.0 1.1 9.2 17.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF913 PF06025.12 EKX31014.1 - 0.87 8.5 3.9 2.2 7.1 3.8 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) RNA_pol_3_Rpc31 PF11705.8 EKX31014.1 - 1 9.6 25.4 2 8.6 25.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 EKX31014.1 - 1.3 8.3 20.0 2.1 7.6 20.0 1.2 1 0 0 1 1 1 0 BUD22 Trypan_PARP PF05887.11 EKX31014.1 - 1.8 8.6 12.6 4.1 7.4 12.6 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SAPS PF04499.15 EKX31014.1 - 2.2 7.0 7.1 3.6 6.3 7.1 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 EKX31014.1 - 2.7 6.2 20.1 4.3 5.5 20.1 1.2 1 0 0 1 1 1 0 CDC45-like protein PTPRCAP PF15713.5 EKX31014.1 - 3.9 7.8 20.1 8.4 6.7 20.1 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Vfa1 PF08432.10 EKX31014.1 - 4.8 7.5 12.1 9 6.6 12.1 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Paf1 PF03985.13 EKX31014.1 - 6.7 5.6 21.5 11 4.9 21.5 1.2 1 0 0 1 1 1 0 Paf1 PPP4R2 PF09184.11 EKX31014.1 - 8.5 5.9 23.3 14 5.1 23.3 1.3 1 0 0 1 1 1 0 PPP4R2 NPR3 PF03666.13 EKX31014.1 - 9.6 4.9 8.3 15 4.2 8.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 S-methyl_trans PF02574.16 EKX31017.1 - 0.065 13.0 0.1 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 Homocysteine S-methyltransferase Beta_helix PF13229.6 EKX31021.1 - 0.00074 19.4 0.0 0.00099 19.0 0.0 1.2 1 0 0 1 1 1 1 Right handed beta helix region FYRN PF05964.14 EKX31022.1 - 1.2e-17 63.5 0.0 2.3e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 EKX31022.1 - 1.2e-14 54.2 0.0 3e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 F/Y rich C-terminus DUF2151 PF10221.9 EKX31022.1 - 1.4e-12 47.1 1.1 2.3e-11 43.1 1.1 2.0 1 1 0 1 1 1 1 Cell cycle and development regulator Ank_2 PF12796.7 EKX31023.1 - 2.3e-55 185.1 0.1 5.4e-10 39.7 0.0 5.4 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX31023.1 - 3.1e-46 155.2 1.9 7.7e-09 35.9 0.0 6.5 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX31023.1 - 4.2e-27 93.9 2.5 0.051 13.9 0.0 9.3 2 1 6 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX31023.1 - 3e-26 88.6 0.0 0.051 14.1 0.0 9.0 10 0 0 10 10 9 7 Ankyrin repeat Ank PF00023.30 EKX31023.1 - 4.1e-14 52.3 0.1 15 6.2 0.0 9.5 10 0 0 10 10 10 1 Ankyrin repeat Chol_subst-bind PF09129.11 EKX31023.1 - 0.0011 17.9 0.0 19 4.0 0.0 5.3 2 2 3 6 6 6 0 Cholesterol oxidase, substrate-binding Ins_beta PF03488.14 EKX31023.1 - 0.0013 18.7 20.5 31 4.7 0.1 8.5 9 0 0 9 9 9 0 Nematode insulin-related peptide beta type DUF640 PF04852.12 EKX31023.1 - 0.018 15.2 1.4 3.6 7.8 0.0 4.2 3 2 1 4 4 4 0 Protein of unknown function (DUF640) VHS PF00790.19 EKX31023.1 - 0.024 14.5 4.1 1.6e+02 2.1 0.0 6.3 7 1 0 7 7 7 0 VHS domain DUF4127 PF13552.6 EKX31023.1 - 0.081 11.5 0.3 3.4 6.1 0.1 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF4127) Imm17 PF15562.6 EKX31023.1 - 0.15 11.9 0.0 25 4.8 0.0 4.5 8 0 0 8 8 8 0 Immunity protein 17 PDZ_2 PF13180.6 EKX31025.1 - 3.7e-05 23.9 0.1 0.00014 22.1 0.1 2.0 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX31025.1 - 0.00044 20.2 0.1 0.0023 17.9 0.0 2.2 2 0 0 2 2 2 1 Tricorn protease PDZ domain PDZ PF00595.24 EKX31025.1 - 0.0035 17.7 0.0 0.011 16.1 0.0 1.9 1 0 0 1 1 1 1 PDZ domain TRAUB PF08164.12 EKX31025.1 - 0.0066 16.9 6.5 1.6 9.3 1.0 4.0 3 0 0 3 3 3 2 Apoptosis-antagonizing transcription factor, C-terminal PDZ_6 PF17820.1 EKX31025.1 - 0.068 13.0 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 PDZ domain DUF4200 PF13863.6 EKX31025.1 - 6.3 7.2 50.8 0.98 9.8 8.0 4.8 1 1 3 4 4 4 0 Domain of unknown function (DUF4200) DUF4407 PF14362.6 EKX31025.1 - 6.9 5.9 36.2 1.5 8.1 15.0 3.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) DUF3185 PF11381.8 EKX31026.1 - 0.087 12.8 0.1 0.087 12.8 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) PIG-P PF08510.12 EKX31026.1 - 0.12 12.3 0.4 0.24 11.3 0.0 1.6 2 0 0 2 2 2 0 PIG-P Pkinase PF00069.25 EKX31028.1 - 7.8e-53 179.5 0.0 1.3e-52 178.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX31028.1 - 3.2e-30 105.3 0.0 4.4e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX31028.1 - 6.1e-08 32.3 0.0 7.9e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EKX31028.1 - 0.19 11.6 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-B_box PF00643.24 EKX31029.1 - 9.2e-06 25.7 7.1 1.7e-05 24.9 7.1 1.4 1 0 0 1 1 1 1 B-box zinc finger Ion_trans_2 PF07885.16 EKX31032.1 - 5.7e-10 39.0 2.5 5.7e-10 39.0 2.5 2.0 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 EKX31032.1 - 3.6e-06 26.4 0.8 6.9e-06 25.5 0.8 1.4 1 0 0 1 1 1 1 Ion transport protein Lig_chan PF00060.26 EKX31032.1 - 5.4e-05 23.1 0.1 0.00014 21.7 0.1 1.7 1 0 0 1 1 1 1 Ligand-gated ion channel Pkinase PF00069.25 EKX31033.1 - 2.2e-55 187.9 0.0 2.7e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX31033.1 - 1.6e-16 60.4 0.0 2.1e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX31033.1 - 0.025 14.5 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EKX31033.1 - 0.031 13.9 0.1 0.073 12.6 0.0 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 EKX31033.1 - 0.047 13.0 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EKX31033.1 - 0.089 12.4 0.0 0.37 10.4 0.0 1.9 1 1 1 2 2 2 0 RIO1 family DUF1664 PF07889.12 EKX31034.1 - 0.02 14.9 34.1 0.05 13.7 1.3 4.6 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) Syntaxin PF00804.25 EKX31034.1 - 0.043 13.5 28.2 0.081 12.6 5.3 4.5 4 1 0 4 4 4 0 Syntaxin Prok-E2_B PF14461.6 EKX31034.1 - 0.073 12.8 0.1 0.35 10.6 0.1 2.2 1 0 0 1 1 1 0 Prokaryotic E2 family B LOH1CR12 PF10158.9 EKX31034.1 - 0.14 12.2 10.7 0.19 11.7 0.6 3.4 3 0 0 3 3 3 0 Tumour suppressor protein DUF2703 PF10865.8 EKX31034.1 - 0.71 10.1 12.0 2.3 8.4 0.7 4.2 3 2 0 3 3 3 0 Domain of unknown function (DUF2703) Metal_resist PF13801.6 EKX31034.1 - 0.81 9.9 20.5 0.38 10.9 1.3 4.2 3 2 0 3 3 3 0 Heavy-metal resistance DUF3708 PF12501.8 EKX31034.1 - 1.8 8.3 8.9 4.4 7.1 0.8 3.2 3 0 0 3 3 3 0 Phosphate ATP-binding cassette transporter GatB_Yqey PF02637.18 EKX31034.1 - 3.5 7.5 11.6 0.87 9.5 1.9 3.2 2 1 0 2 2 2 0 GatB domain Cytochrom_C_2 PF01322.20 EKX31034.1 - 9.2 7.2 13.7 5.2 8.0 1.3 4.3 3 2 0 3 3 3 0 Cytochrome C' WD40 PF00400.32 EKX31035.1 - 8.3e-05 23.3 7.5 2.5 9.1 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_3 PF13570.6 EKX31035.1 - 0.74 10.4 0.0 0.74 10.4 0.0 3.4 3 2 1 4 4 4 0 PQQ-like domain GldM_N PF12081.8 EKX31036.1 - 1.8 8.6 19.1 7.8 6.5 8.5 2.5 1 1 1 2 2 2 0 GldM N-terminal domain DUF4407 PF14362.6 EKX31038.1 - 8.8 5.6 28.8 17 4.6 28.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SpoIIE PF07228.12 EKX31039.1 - 0.016 15.1 0.1 0.023 14.6 0.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Baculo_PEP_C PF04513.12 EKX31041.1 - 3.3e-09 36.9 0.3 5.2e-09 36.3 0.3 1.4 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.13 EKX31041.1 - 7.7e-07 29.4 10.2 0.00014 22.2 1.6 3.4 1 1 2 3 3 3 3 Lipoprotein leucine-zipper Apolipoprotein PF01442.18 EKX31041.1 - 6.6e-06 26.1 2.1 9.9e-06 25.6 2.1 1.3 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 EKX31041.1 - 8.6e-06 25.8 2.6 1e-05 25.6 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 EKX31041.1 - 2e-05 24.8 1.0 2.5e-05 24.5 1.0 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Prefoldin_2 PF01920.20 EKX31041.1 - 3e-05 23.9 5.9 0.0074 16.2 0.6 2.1 1 1 1 2 2 2 2 Prefoldin subunit Spc7 PF08317.11 EKX31041.1 - 9.8e-05 21.4 2.6 0.00011 21.2 2.6 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein TolA_bind_tri PF16331.5 EKX31041.1 - 0.0002 21.4 0.6 0.02 14.9 0.1 2.6 1 1 1 2 2 2 1 TolA binding protein trimerisation DUF5082 PF16888.5 EKX31041.1 - 0.00029 21.1 0.9 0.00038 20.7 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) Filament PF00038.21 EKX31041.1 - 0.00034 20.3 0.7 0.00037 20.2 0.7 1.1 1 0 0 1 1 1 1 Intermediate filament protein CENP-F_leu_zip PF10473.9 EKX31041.1 - 0.00034 20.6 3.5 0.00039 20.4 3.5 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 EKX31041.1 - 0.00035 20.9 1.6 0.001 19.5 0.2 2.0 1 1 1 2 2 2 1 Cell division protein ZapB TPR_MLP1_2 PF07926.12 EKX31041.1 - 0.0004 20.5 0.7 0.00054 20.0 0.7 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF16 PF01519.16 EKX31041.1 - 0.00042 20.8 2.9 0.0008 19.9 2.9 1.5 1 1 0 1 1 1 1 Protein of unknown function DUF16 bZIP_1 PF00170.21 EKX31041.1 - 0.00048 20.2 2.6 0.0015 18.6 0.3 2.2 1 1 1 2 2 2 1 bZIP transcription factor SKA2 PF16740.5 EKX31041.1 - 0.00052 19.8 0.7 0.00062 19.5 0.7 1.2 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 CdvA PF18822.1 EKX31041.1 - 0.00057 19.7 2.1 0.0023 17.8 0.6 2.0 1 1 1 2 2 2 1 CdvA-like coiled-coil domain YtxH PF12732.7 EKX31041.1 - 0.00057 20.4 5.3 0.037 14.5 5.3 2.2 1 1 0 1 1 1 1 YtxH-like protein Bacillus_HBL PF05791.11 EKX31041.1 - 0.00086 19.2 2.2 0.0009 19.1 2.2 1.1 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) DUF641 PF04859.12 EKX31041.1 - 0.00098 19.5 0.6 0.0011 19.3 0.6 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) ApoLp-III PF07464.11 EKX31041.1 - 0.0013 18.8 1.3 0.0017 18.5 1.3 1.3 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) DivIC PF04977.15 EKX31041.1 - 0.0014 18.4 1.6 0.0078 16.0 1.9 1.9 1 1 0 1 1 1 1 Septum formation initiator DUF2730 PF10805.8 EKX31041.1 - 0.0014 18.7 1.9 0.003 17.6 1.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2730) Syntaxin-6_N PF09177.11 EKX31041.1 - 0.0015 19.1 3.1 0.002 18.6 3.1 1.3 1 1 0 1 1 1 1 Syntaxin 6, N-terminal Alanine_zipper PF11839.8 EKX31041.1 - 0.0015 18.8 0.3 0.22 11.9 0.0 2.6 1 1 2 3 3 3 1 Alanine-zipper, major outer membrane lipoprotein Kre28 PF17097.5 EKX31041.1 - 0.0016 17.5 2.7 0.0016 17.5 2.0 1.4 1 1 0 1 1 1 1 Spindle pole body component EzrA PF06160.12 EKX31041.1 - 0.0016 16.7 1.6 0.0016 16.7 1.6 1.0 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF2205 PF10224.9 EKX31041.1 - 0.0016 18.4 2.3 0.0025 17.8 2.2 1.5 1 1 0 1 1 1 1 Short coiled-coil protein COG5 PF10392.9 EKX31041.1 - 0.0017 18.5 1.8 0.0024 18.1 1.8 1.3 1 1 0 1 1 1 1 Golgi transport complex subunit 5 Fzo_mitofusin PF04799.13 EKX31041.1 - 0.002 17.7 1.5 0.0038 16.8 1.5 1.6 1 1 0 1 1 1 1 fzo-like conserved region PspA_IM30 PF04012.12 EKX31041.1 - 0.0021 17.7 0.2 0.0022 17.6 0.2 1.2 1 0 0 1 1 1 1 PspA/IM30 family KxDL PF10241.9 EKX31041.1 - 0.0021 18.3 0.9 0.009 16.3 0.2 1.8 1 1 1 2 2 2 1 Uncharacterized conserved protein KASH_CCD PF14662.6 EKX31041.1 - 0.0024 17.7 2.1 0.0026 17.6 2.1 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Jnk-SapK_ap_N PF09744.9 EKX31041.1 - 0.0025 18.1 1.7 0.0026 18.0 1.7 1.1 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Phage_GPO PF05929.11 EKX31041.1 - 0.0026 17.4 1.3 0.0027 17.4 1.3 1.0 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase HIP1_clath_bdg PF16515.5 EKX31041.1 - 0.0029 18.2 2.6 0.0033 18.0 2.6 1.2 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Vps51 PF08700.11 EKX31041.1 - 0.003 17.6 0.9 0.0043 17.1 0.9 1.3 1 1 0 1 1 1 1 Vps51/Vps67 FPP PF05911.11 EKX31041.1 - 0.0031 15.8 1.9 0.0033 15.7 1.9 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil FlaC_arch PF05377.11 EKX31041.1 - 0.0032 17.8 2.1 0.0032 17.8 2.1 2.5 1 1 2 3 3 3 1 Flagella accessory protein C (FlaC) DUF4618 PF15397.6 EKX31041.1 - 0.0035 16.8 2.5 0.012 15.1 2.8 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4618) HALZ PF02183.18 EKX31041.1 - 0.0037 17.5 6.1 0.27 11.5 4.7 3.4 1 1 0 1 1 1 1 Homeobox associated leucine zipper ADIP PF11559.8 EKX31041.1 - 0.0039 17.3 1.1 0.0043 17.1 1.1 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding TACC_C PF05010.14 EKX31041.1 - 0.0039 17.0 0.8 0.017 14.9 0.9 1.7 1 1 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Seryl_tRNA_N PF02403.22 EKX31041.1 - 0.004 17.4 2.1 0.0053 17.0 2.1 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Sec8_exocyst PF04048.14 EKX31041.1 - 0.0041 17.0 0.6 0.0043 16.9 0.6 1.1 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain NPV_P10 PF05531.12 EKX31041.1 - 0.0042 17.5 5.8 0.018 15.5 2.4 2.4 1 1 1 2 2 2 2 Nucleopolyhedrovirus P10 protein DUF812 PF05667.11 EKX31041.1 - 0.005 15.8 1.4 0.0051 15.8 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Tektin PF03148.14 EKX31041.1 - 0.005 15.6 0.7 0.0055 15.5 0.7 1.0 1 0 0 1 1 1 1 Tektin family UPF0449 PF15136.6 EKX31041.1 - 0.005 17.3 1.8 0.011 16.1 1.8 1.7 1 1 0 1 1 1 1 Uncharacterised protein family UPF0449 TSC22 PF01166.18 EKX31041.1 - 0.0055 17.0 1.1 0.03 14.6 1.1 2.3 1 1 0 1 1 1 1 TSC-22/dip/bun family DUF4795 PF16043.5 EKX31041.1 - 0.0056 16.3 4.5 0.062 12.9 1.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4795) YabA PF06156.13 EKX31041.1 - 0.0056 17.3 0.6 0.014 16.0 0.6 1.7 1 1 0 1 1 1 1 Initiation control protein YabA BLOC1_2 PF10046.9 EKX31041.1 - 0.0057 16.9 1.9 0.0096 16.2 1.9 1.5 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Vps53_N PF04100.12 EKX31041.1 - 0.0058 15.6 2.3 0.0059 15.6 2.3 1.0 1 0 0 1 1 1 1 Vps53-like, N-terminal Fez1 PF06818.15 EKX31041.1 - 0.0061 17.0 2.0 0.0065 16.9 2.0 1.1 1 0 0 1 1 1 1 Fez1 Laminin_II PF06009.12 EKX31041.1 - 0.0068 16.4 2.5 0.011 15.8 1.2 1.7 1 1 0 1 1 1 1 Laminin Domain II HMMR_C PF15908.5 EKX31041.1 - 0.0068 16.7 1.8 0.012 15.9 0.4 1.8 1 1 1 2 2 2 1 Hyaluronan mediated motility receptor C-terminal DUF1640 PF07798.11 EKX31041.1 - 0.0073 16.4 3.7 0.021 14.9 3.7 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1640) CALCOCO1 PF07888.11 EKX31041.1 - 0.0078 15.1 2.2 0.0096 14.8 2.2 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Phage_GP20 PF06810.11 EKX31041.1 - 0.0084 15.9 3.9 0.038 13.8 3.9 1.8 1 1 0 1 1 1 1 Phage minor structural protein GP20 YlqD PF11068.8 EKX31041.1 - 0.0087 16.4 0.4 0.0096 16.3 0.4 1.0 1 0 0 1 1 1 1 YlqD protein H-kinase_dim PF02895.14 EKX31041.1 - 0.0087 16.4 1.3 3.1 8.3 0.1 2.2 1 1 1 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Rootletin PF15035.6 EKX31041.1 - 0.0096 16.0 1.9 0.013 15.6 1.9 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Tup_N PF08581.10 EKX31041.1 - 0.0096 16.2 3.0 0.014 15.6 3.0 1.4 1 1 0 1 1 1 1 Tup N-terminal GCN5L1 PF06320.13 EKX31041.1 - 0.01 16.0 0.7 0.011 15.8 0.7 1.1 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) DUF2884 PF11101.8 EKX31041.1 - 0.011 15.3 0.3 0.014 15.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Atg14 PF10186.9 EKX31041.1 - 0.011 14.9 0.4 0.011 14.8 0.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_13 PF13166.6 EKX31041.1 - 0.011 14.4 0.8 0.011 14.4 0.8 1.0 1 0 0 1 1 1 0 AAA domain XhlA PF10779.9 EKX31041.1 - 0.013 15.7 4.2 0.06 13.5 1.5 2.2 1 1 1 2 2 2 0 Haemolysin XhlA Phasin PF05597.11 EKX31041.1 - 0.013 15.5 2.8 0.019 15.0 2.8 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1515 PF07439.11 EKX31041.1 - 0.013 15.5 1.9 0.031 14.3 1.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) NleF_casp_inhib PF16809.5 EKX31041.1 - 0.014 15.3 1.8 0.021 14.7 1.8 1.3 1 1 0 1 1 1 0 NleF caspase inhibitor SlyX PF04102.12 EKX31041.1 - 0.014 16.0 0.2 0.041 14.5 0.1 1.7 1 1 1 2 2 1 0 SlyX DUF4472 PF14739.6 EKX31041.1 - 0.014 16.1 1.7 0.043 14.5 1.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4472) DUF2968 PF11180.8 EKX31041.1 - 0.016 14.9 0.5 0.019 14.6 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF3584 PF12128.8 EKX31041.1 - 0.017 12.7 2.0 0.018 12.6 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MIP-T3_C PF17749.1 EKX31041.1 - 0.018 15.0 1.2 0.021 14.8 1.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region Occludin_ELL PF07303.13 EKX31041.1 - 0.018 15.8 0.6 0.13 13.0 0.7 2.0 1 1 0 1 1 1 0 Occludin homology domain DUF4407 PF14362.6 EKX31041.1 - 0.018 14.4 0.5 0.02 14.2 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FliD_N PF02465.18 EKX31041.1 - 0.018 15.7 1.1 0.035 14.8 1.1 1.6 1 1 1 2 2 1 0 Flagellar hook-associated protein 2 N-terminus Prominin PF05478.11 EKX31041.1 - 0.018 13.0 0.8 0.018 13.0 0.8 1.0 1 0 0 1 1 1 0 Prominin WXG100 PF06013.12 EKX31041.1 - 0.019 15.2 0.2 0.28 11.4 0.1 2.2 1 1 2 3 3 3 0 Proteins of 100 residues with WXG COG2 PF06148.11 EKX31041.1 - 0.02 15.0 4.3 0.034 14.2 4.3 1.5 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 TMF_DNA_bd PF12329.8 EKX31041.1 - 0.02 14.9 1.1 0.02 14.9 1.1 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Spectrin PF00435.21 EKX31041.1 - 0.021 15.3 0.7 4.2 7.9 0.1 2.1 1 1 1 2 2 2 0 Spectrin repeat Phage_Mu_Gam PF07352.12 EKX31041.1 - 0.021 14.7 0.1 0.062 13.2 0.1 1.6 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein DLP_helical PF18709.1 EKX31041.1 - 0.021 14.0 1.0 0.056 12.6 0.3 1.6 1 1 0 1 1 1 0 Dynamin-like helical domain GAS PF13851.6 EKX31041.1 - 0.021 14.2 1.8 0.034 13.5 1.8 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 EKX31041.1 - 0.022 15.0 2.4 0.034 14.4 2.1 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) THOC7 PF05615.13 EKX31041.1 - 0.023 15.0 0.9 0.029 14.7 0.9 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 LXG PF04740.12 EKX31041.1 - 0.023 14.4 2.5 0.18 11.5 2.5 2.1 1 1 0 1 1 1 0 LXG domain of WXG superfamily SH3BP5 PF05276.14 EKX31041.1 - 0.026 14.3 0.2 0.15 11.8 0.1 2.0 1 1 1 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) DUF148 PF02520.17 EKX31041.1 - 0.027 14.6 0.5 0.047 13.8 0.5 1.5 1 1 0 1 1 1 0 Domain of unknown function DUF148 Erp_C PF06780.11 EKX31041.1 - 0.027 14.5 7.3 0.14 12.1 7.3 2.3 1 1 0 1 1 1 0 Erp protein C-terminus V-SNARE PF05008.15 EKX31041.1 - 0.027 14.8 1.3 0.043 14.2 1.3 1.4 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus TSNAXIP1_N PF15739.5 EKX31041.1 - 0.027 14.8 0.5 0.034 14.5 0.5 1.3 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus HSCB_C PF07743.13 EKX31041.1 - 0.028 14.9 1.5 0.073 13.6 1.5 1.8 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain TMF_TATA_bd PF12325.8 EKX31041.1 - 0.028 14.6 6.8 0.16 12.2 6.8 2.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4164 PF13747.6 EKX31041.1 - 0.028 14.7 2.6 0.062 13.6 2.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) YscO PF07321.12 EKX31041.1 - 0.029 14.3 0.5 0.059 13.3 0.5 1.6 1 1 0 1 1 1 0 Type III secretion protein YscO DUF713 PF05218.14 EKX31041.1 - 0.031 14.0 1.1 0.044 13.5 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF713) RmuC PF02646.16 EKX31041.1 - 0.031 13.4 1.4 0.039 13.1 1.4 1.1 1 0 0 1 1 1 0 RmuC family Packaging_FI PF14000.6 EKX31041.1 - 0.032 14.7 2.9 0.038 14.4 2.9 1.2 1 0 0 1 1 1 0 DNA packaging protein FI DUF4200 PF13863.6 EKX31041.1 - 0.032 14.6 0.8 0.037 14.4 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF948 PF06103.11 EKX31041.1 - 0.032 14.5 2.8 0.15 12.3 2.8 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Lectin_N PF03954.14 EKX31041.1 - 0.035 13.9 1.9 0.04 13.7 1.9 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF4988 PF16378.5 EKX31041.1 - 0.035 13.8 0.8 0.32 10.6 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function Tropomyosin_1 PF12718.7 EKX31041.1 - 0.037 14.2 5.3 0.096 12.8 5.3 1.6 1 1 0 1 1 1 0 Tropomyosin like DUF724 PF05266.14 EKX31041.1 - 0.038 13.8 0.9 0.039 13.8 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) SKA1 PF07160.12 EKX31041.1 - 0.038 13.8 0.2 0.043 13.6 0.2 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 UPF0242 PF06785.11 EKX31041.1 - 0.041 14.0 2.0 0.041 14.0 2.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 EKX31041.1 - 0.041 14.4 2.5 0.052 14.1 2.5 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Zw10 PF06248.13 EKX31041.1 - 0.041 12.4 2.1 0.047 12.3 2.1 1.0 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 COG6 PF06419.11 EKX31041.1 - 0.044 12.0 1.8 0.043 12.0 1.8 1.0 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 ING PF12998.7 EKX31041.1 - 0.046 14.3 2.5 0.07 13.7 2.5 1.4 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding DASH_Dam1 PF08653.10 EKX31041.1 - 0.047 13.5 3.8 5.4 6.9 0.2 3.0 1 1 1 3 3 3 0 DASH complex subunit Dam1 Muted PF14942.6 EKX31041.1 - 0.051 13.9 4.2 2 8.8 0.4 2.0 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Cnn_1N PF07989.11 EKX31041.1 - 0.052 13.7 4.5 0.82 9.9 4.5 2.1 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 DUF883 PF05957.13 EKX31041.1 - 0.052 14.2 2.3 0.7 10.5 0.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) TMPIT PF07851.13 EKX31041.1 - 0.056 12.7 0.6 0.059 12.6 0.6 1.0 1 0 0 1 1 1 0 TMPIT-like protein Tweety PF04906.13 EKX31041.1 - 0.061 12.0 0.5 0.06 12.0 0.5 1.0 1 0 0 1 1 1 0 Tweety Ax_dynein_light PF10211.9 EKX31041.1 - 0.068 13.1 1.2 0.13 12.2 1.2 1.6 1 1 0 1 1 1 0 Axonemal dynein light chain Prefoldin PF02996.17 EKX31041.1 - 0.068 13.1 1.4 0.14 12.1 0.4 1.9 1 1 1 2 2 2 0 Prefoldin subunit NAS PF03059.16 EKX31041.1 - 0.069 12.5 0.1 0.069 12.5 0.1 1.1 1 0 0 1 1 1 0 Nicotianamine synthase protein FAM76 PF16046.5 EKX31041.1 - 0.071 12.5 1.0 0.085 12.2 1.0 1.2 1 0 0 1 1 1 0 FAM76 protein Snapin_Pallidin PF14712.6 EKX31041.1 - 0.079 13.4 2.3 0.35 11.3 1.2 2.1 1 1 1 2 2 2 0 Snapin/Pallidin MbeD_MobD PF04899.12 EKX31041.1 - 0.087 13.0 0.8 0.2 11.8 0.7 1.8 1 1 0 1 1 1 0 MbeD/MobD like CLZ PF16526.5 EKX31041.1 - 0.089 13.2 2.3 0.37 11.2 2.3 2.1 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_2 PF07716.15 EKX31041.1 - 0.1 12.7 0.4 12 6.1 0.0 2.7 1 1 2 3 3 2 0 Basic region leucine zipper WD40_alt PF14077.6 EKX31041.1 - 0.11 12.4 6.7 1.9 8.4 0.4 3.6 1 1 1 3 3 3 0 Alternative WD40 repeat motif JIP_LZII PF16471.5 EKX31041.1 - 0.11 12.6 3.9 0.25 11.6 3.8 1.7 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II DivIVA PF05103.13 EKX31041.1 - 0.11 12.5 2.8 0.1 12.7 1.0 1.7 1 1 1 2 2 2 0 DivIVA protein V_ATPase_I PF01496.19 EKX31041.1 - 0.13 10.2 1.0 0.13 10.2 1.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Swi5 PF07061.11 EKX31041.1 - 0.14 12.3 1.7 0.68 10.1 0.3 2.4 1 1 1 2 2 2 0 Swi5 BST2 PF16716.5 EKX31041.1 - 0.14 12.7 2.0 0.62 10.7 2.0 2.0 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 ZYG-11_interact PF05884.12 EKX31041.1 - 0.16 11.4 0.5 0.16 11.3 0.5 1.0 1 0 0 1 1 1 0 Interactor of ZYG-11 SICA_alpha PF12887.7 EKX31041.1 - 0.2 11.5 1.1 1.1 9.1 1.1 2.0 1 1 0 1 1 1 0 SICA extracellular alpha domain RapH_N PF18801.1 EKX31041.1 - 0.27 11.3 1.5 14 5.8 0.1 2.7 1 1 2 3 3 2 0 response regulator aspartate phosphatase H, N terminal DUF2746 PF10874.8 EKX31041.1 - 0.46 10.9 3.5 2.4 8.6 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2746) Sas10_Utp3 PF04000.15 EKX31041.1 - 0.54 10.9 4.2 2.1 9.0 4.2 2.1 1 1 0 1 1 1 0 Sas10/Utp3/C1D family AKNA PF12443.8 EKX31041.1 - 0.56 10.9 3.6 8.7 7.1 0.1 2.9 1 1 2 3 3 2 0 AT-hook-containing transcription factor DNAPolymera_Pol PF11590.8 EKX31042.1 - 0.091 12.7 0.2 0.73 9.8 0.1 2.2 2 0 0 2 2 2 0 DNA polymerase catalytic subunit Pol Ion_trans PF00520.31 EKX31043.1 - 6.3e-14 51.8 6.7 9e-14 51.3 6.7 1.2 1 0 0 1 1 1 1 Ion transport protein PH PF00169.29 EKX31043.1 - 5.5e-05 23.6 0.1 0.0002 21.8 0.1 2.0 1 1 0 1 1 1 1 PH domain CLZ PF16526.5 EKX31043.1 - 0.0018 18.6 5.3 0.0052 17.1 5.3 1.8 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF724 PF05266.14 EKX31043.1 - 0.28 11.0 13.1 0.62 9.9 13.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FA_desaturase PF00487.24 EKX31044.1 - 3.7 7.3 8.9 4.4 7.1 8.9 1.2 1 0 0 1 1 1 0 Fatty acid desaturase DUF1700 PF08006.11 EKX31044.1 - 4.2 6.9 16.4 5.7 6.4 16.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF3400 PF11880.8 EKX31045.1 - 0.017 14.7 0.2 0.053 13.0 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) SNF2_N PF00176.23 EKX31046.1 - 6.1e-71 239.0 0.0 1.1e-70 238.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 EKX31046.1 - 1.7e-41 140.8 4.3 5.5e-41 139.2 4.3 2.0 1 0 0 1 1 1 1 SLIDE Helicase_C PF00271.31 EKX31046.1 - 7.7e-23 81.0 0.1 3.7e-21 75.5 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HAND PF09110.11 EKX31046.1 - 3.1e-12 47.2 3.2 1.2e-11 45.3 3.2 2.1 1 0 0 1 1 1 1 HAND Myb_DNA-binding PF00249.31 EKX31046.1 - 1.9e-09 37.6 10.2 1.5e-05 25.0 0.1 3.8 3 1 0 3 3 3 2 Myb-like DNA-binding domain ResIII PF04851.15 EKX31046.1 - 7.9e-09 35.7 0.0 3.1e-08 33.8 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EKX31046.1 - 2.4e-06 26.9 0.0 1.1e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 EKX31046.1 - 1.4e-05 25.0 0.0 3.7e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EKX31046.1 - 0.00023 20.9 0.0 0.00066 19.4 0.0 1.7 2 0 0 2 2 2 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 EKX31046.1 - 0.026 13.7 0.0 0.06 12.5 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase LOB PF03195.14 EKX31048.1 - 0.15 12.6 2.1 0.89 10.2 1.2 2.2 2 0 0 2 2 2 0 Lateral organ boundaries (LOB) domain Myb_DNA-binding PF00249.31 EKX31050.1 - 1.9e-08 34.3 0.1 9e-08 32.2 0.1 2.0 1 1 0 1 1 1 1 Myb-like DNA-binding domain TPR_1 PF00515.28 EKX31053.1 - 9.1e-16 56.9 0.8 3.8e-08 32.8 0.1 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX31053.1 - 7.6e-13 47.9 5.2 2.6e-09 36.6 2.0 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.17 EKX31053.1 - 2.3e-12 46.0 3.2 2.8e-06 27.0 0.2 2.5 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX31053.1 - 5e-10 38.8 2.6 8.5e-07 28.7 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX31053.1 - 1.1e-08 35.6 0.3 1.8e-08 34.9 0.3 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX31053.1 - 1.2e-08 34.8 2.0 4.6e-06 26.6 0.8 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX31053.1 - 2.4e-08 34.2 7.0 2.3e-05 24.6 1.4 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX31053.1 - 8e-07 28.7 0.8 0.036 14.1 0.1 2.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX31053.1 - 2.3e-06 27.9 0.1 0.00047 20.8 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX31053.1 - 1.4e-05 25.5 1.9 2.5e-05 24.7 1.9 1.4 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX31053.1 - 2e-05 24.7 0.1 2.6e-05 24.3 0.1 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat MIT PF04212.18 EKX31053.1 - 0.0009 19.3 2.2 0.042 13.9 0.0 2.4 2 1 0 2 2 2 1 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 EKX31053.1 - 0.002 18.3 1.9 0.0026 17.9 1.9 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EKX31053.1 - 0.004 17.7 0.2 0.071 13.8 0.0 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat MAS20 PF02064.15 EKX31053.1 - 0.011 15.9 0.1 0.16 12.0 0.1 2.0 1 1 0 1 1 1 0 MAS20 protein import receptor DUF2225 PF09986.9 EKX31053.1 - 0.044 13.5 1.2 0.049 13.3 1.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) RPN7 PF10602.9 EKX31053.1 - 0.051 13.3 2.2 0.39 10.4 0.8 2.5 1 1 2 3 3 3 0 26S proteasome subunit RPN7 TPR_20 PF14561.6 EKX31053.1 - 0.063 13.6 1.0 0.098 13.0 0.3 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX31053.1 - 0.11 12.3 1.1 1.5 8.8 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 EKX31054.1 - 9.4e-20 71.1 0.0 1e-19 70.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX31054.1 - 5e-09 35.8 0.0 5.3e-09 35.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX31054.1 - 0.0049 15.7 0.0 0.0053 15.6 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX31054.1 - 0.033 14.1 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Snapin_Pallidin PF14712.6 EKX31056.1 - 0.0023 18.3 0.9 0.0034 17.8 0.9 1.2 1 0 0 1 1 1 1 Snapin/Pallidin SesA PF17107.5 EKX31056.1 - 0.0029 17.8 0.3 0.0048 17.1 0.3 1.3 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases CENP-Q PF13094.6 EKX31056.1 - 0.02 15.1 0.2 0.02 15.1 0.2 1.5 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit CLZ PF16526.5 EKX31056.1 - 0.031 14.6 1.6 0.054 13.9 1.6 1.4 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 EKX31056.1 - 0.051 14.0 0.5 0.08 13.4 0.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein ADK PF00406.22 EKX31057.1 - 2.4e-14 53.7 2.1 4.7e-13 49.5 2.1 2.7 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EKX31057.1 - 1.4e-07 32.0 4.1 1.5e-07 31.9 0.1 2.6 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 EKX31057.1 - 0.0086 16.6 0.0 0.046 14.3 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 EKX31057.1 - 0.04 14.1 0.9 2.6 8.2 0.1 2.9 4 0 0 4 4 4 0 AAA domain AAA PF00004.29 EKX31057.1 - 0.074 13.5 0.3 1.4 9.3 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EKX31057.1 - 0.076 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain CBM32 PF18344.1 EKX31057.1 - 0.11 12.4 0.1 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 Carbohydrate binding module family 32 Med15_fungi PF05397.12 EKX31057.1 - 0.21 11.9 1.3 0.79 10.0 0.4 2.3 2 0 0 2 2 2 0 Mediator complex subunit 15 Mt_ATP-synt_B PF05405.14 EKX31057.1 - 0.48 10.0 4.0 0.46 10.1 2.1 1.9 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) C2 PF00168.30 EKX31058.1 - 3.4e-13 49.8 0.1 0.0083 16.4 0.0 4.4 3 1 0 3 3 3 3 C2 domain OmpH PF03938.14 EKX31058.1 - 0.019 15.3 6.7 0.019 15.3 6.7 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) MRF_C1 PF13887.6 EKX31058.1 - 0.027 13.6 0.1 0.077 12.2 0.1 1.8 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 TFIIB PF00382.19 EKX31058.1 - 0.059 13.4 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 Transcription factor TFIIB repeat DMPK_coil PF08826.10 EKX31058.1 - 0.061 13.5 8.9 0.15 12.2 8.9 1.6 1 0 0 1 1 1 0 DMPK coiled coil domain like TMPIT PF07851.13 EKX31058.1 - 0.58 9.3 6.4 0.96 8.6 6.4 1.3 1 0 0 1 1 1 0 TMPIT-like protein EF-hand_1 PF00036.32 EKX31059.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 EF hand Ion_trans PF00520.31 EKX31060.1 - 6.8e-13 48.4 6.1 8.6e-13 48.1 6.1 1.1 1 0 0 1 1 1 1 Ion transport protein PH PF00169.29 EKX31060.1 - 0.0011 19.4 0.0 0.0032 17.9 0.0 1.8 1 1 0 1 1 1 1 PH domain CSN7a_helixI PF18392.1 EKX31060.1 - 0.084 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain Voltage_CLC PF00654.20 EKX31060.1 - 0.096 11.9 0.1 0.12 11.6 0.1 1.1 1 0 0 1 1 1 0 Voltage gated chloride channel Mpt_N PF09176.11 EKX31061.1 - 0.0005 20.1 3.6 25 5.1 0.1 5.3 1 1 4 5 5 5 1 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal DUF2345 PF10106.9 EKX31061.1 - 0.032 14.1 12.8 0.34 10.8 3.2 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2345) CopB PF05275.11 EKX31061.1 - 0.28 10.7 0.8 0.6 9.6 0.7 1.6 1 1 0 1 1 1 0 Copper resistance protein B precursor (CopB) HTH_10 PF04967.12 EKX31061.1 - 1 9.2 17.8 1.8e+02 2.0 0.1 7.4 5 4 5 11 11 11 0 HTH DNA binding domain Ank_2 PF12796.7 EKX31062.1 - 5.9e-07 30.0 0.0 7.8e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX31062.1 - 4.3e-05 24.0 0.0 0.0045 17.5 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX31062.1 - 6.8e-05 23.1 0.1 0.004 17.4 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX31062.1 - 0.0021 18.4 0.0 0.2 12.2 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EKX31062.1 - 0.0026 18.1 0.0 5.7 7.9 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat SAP PF02037.27 EKX31063.1 - 3.5e-11 42.6 1.3 3.5e-11 42.6 1.3 1.7 2 0 0 2 2 2 1 SAP domain Telomere_Sde2_2 PF13297.6 EKX31063.1 - 9.1e-05 22.0 1.0 0.00013 21.5 1.0 1.2 1 0 0 1 1 1 1 Telomere stability C-terminal RWP-RK PF02042.15 EKX31064.1 - 7.7e-13 48.2 0.1 1.4e-12 47.4 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_31 PF13560.6 EKX31064.1 - 0.064 13.6 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_AraC PF00165.23 EKX31064.1 - 0.11 12.6 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family MttA_Hcf106 PF02416.16 EKX31064.1 - 0.18 11.2 3.2 0.68 9.3 3.3 1.9 1 1 0 1 1 1 0 mttA/Hcf106 family DUF4666 PF15697.5 EKX31064.1 - 0.33 11.7 4.6 0.75 10.5 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) PBP_sp32 PF07222.12 EKX31064.1 - 3.1 7.2 8.4 0.4 10.1 4.4 1.6 2 0 0 2 2 2 0 Proacrosin binding protein sp32 Pkinase_Tyr PF07714.17 EKX31065.1 - 2.2e-38 132.1 0.0 2.4e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX31065.1 - 4.1e-15 55.9 0.0 4.5e-15 55.7 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX31067.1 - 1.2e-54 185.3 0.0 1.4e-54 185.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX31067.1 - 9.5e-22 77.6 0.0 1.2e-21 77.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 EKX31068.1 - 2.8e-37 126.0 27.2 9.3e-08 32.6 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 EKX31068.1 - 0.00013 20.7 1.8 0.47 8.9 0.3 2.9 1 1 3 4 4 4 4 Cytochrome D1 heme domain Nbas_N PF15492.6 EKX31068.1 - 0.00022 20.7 3.2 0.16 11.3 0.2 4.0 1 1 4 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 EKX31068.1 - 0.00023 20.0 11.3 2.9 6.4 0.0 4.9 1 1 2 5 5 5 4 Nucleoporin Nup120/160 VID27 PF08553.10 EKX31068.1 - 0.00072 18.7 1.9 0.31 10.0 0.1 2.3 1 1 1 2 2 2 2 VID27 C-terminal WD40-like domain Nucleoporin_N PF08801.11 EKX31068.1 - 0.0036 16.1 1.2 0.064 12.0 0.2 2.4 1 1 0 2 2 2 1 Nup133 N terminal like WD40_like PF17005.5 EKX31068.1 - 0.0068 15.8 0.0 18 4.5 0.0 4.1 2 2 3 5 5 5 1 WD40-like domain GHD PF17834.1 EKX31068.1 - 0.072 13.2 0.9 85 3.3 0.0 4.3 5 0 0 5 5 5 0 Beta-sandwich domain in beta galactosidase TFIIA PF03153.13 EKX31069.1 - 4e-07 30.4 33.8 5.3e-07 30.0 33.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit GREB1 PF15782.5 EKX31069.1 - 0.28 8.3 15.9 0.33 8.0 15.9 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RVT_1 PF00078.27 EKX31070.1 - 1.5e-07 31.2 0.0 6.1e-05 22.6 0.0 2.4 1 1 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) ORC5_C PF14630.6 EKX31070.1 - 0.0059 16.2 0.5 0.025 14.1 0.2 2.0 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus Sgf11 PF08209.11 EKX31070.1 - 4.1 7.1 5.4 1.3 8.7 1.8 2.0 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Retrotrans_gag PF03732.17 EKX31071.1 - 0.00028 21.1 1.5 0.0077 16.5 0.1 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein bZIP_1 PF00170.21 EKX31071.1 - 1.3 9.2 6.6 11 6.2 0.2 2.5 2 0 0 2 2 2 0 bZIP transcription factor Guanylate_cyc PF00211.20 EKX31073.1 - 3.1e-57 193.2 0.1 4e-57 192.8 0.1 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF4873 PF16170.5 EKX31075.1 - 0.096 12.9 0.2 0.16 12.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4873) RWP-RK PF02042.15 EKX31078.1 - 2.5e-15 56.2 0.1 6.1e-15 54.9 0.1 1.7 1 0 0 1 1 1 1 RWP-RK domain GIT_CC PF16559.5 EKX31079.1 - 0.00019 21.3 11.7 0.31 10.9 0.0 4.4 4 0 0 4 4 4 3 GIT coiled-coil Rho guanine nucleotide exchange factor Cnn_1N PF07989.11 EKX31079.1 - 0.0031 17.6 23.3 0.018 15.2 3.9 4.4 3 1 1 4 4 4 2 Centrosomin N-terminal motif 1 TPR_MLP1_2 PF07926.12 EKX31079.1 - 0.015 15.4 8.2 0.015 15.4 8.2 4.2 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Shugoshin_N PF07558.11 EKX31079.1 - 0.024 14.5 1.3 0.36 10.7 0.0 2.7 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region TSC22 PF01166.18 EKX31079.1 - 0.04 14.2 0.1 0.04 14.2 0.1 4.1 5 0 0 5 5 5 0 TSC-22/dip/bun family YabA PF06156.13 EKX31079.1 - 0.2 12.3 21.5 2.1 9.0 0.4 4.1 1 1 3 4 4 4 0 Initiation control protein YabA DUF4407 PF14362.6 EKX31079.1 - 0.24 10.7 25.4 0.044 13.1 14.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Alph_Pro_TM PF09608.10 EKX31079.1 - 0.79 9.5 2.6 1.1 9.1 1.1 1.7 1 1 1 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) DUF1664 PF07889.12 EKX31079.1 - 1.2 9.2 12.0 0.23 11.5 2.0 3.1 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) NRBF2 PF08961.10 EKX31079.1 - 1.3 8.6 19.4 0.9 9.1 3.8 3.1 1 1 2 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator FlaC_arch PF05377.11 EKX31079.1 - 2.8 8.4 9.6 4.4 7.8 0.5 3.9 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.10 EKX31079.1 - 4.4 7.5 14.2 7.6 6.7 6.8 3.0 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF3037 PF11236.8 EKX31079.1 - 8 6.9 12.6 1.7 9.1 1.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) Rit1_C PF17184.4 EKX31080.1 - 3.9e-09 36.3 0.0 1.3e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 Rit1 N-terminal domain TRCF PF03461.15 EKX31080.1 - 0.092 13.1 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 TRCF domain DUF4087 PF13316.6 EKX31080.1 - 0.14 12.6 0.1 0.29 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4087) SLT_beta PF02258.16 EKX31083.1 - 0.0022 18.0 13.4 8.7 6.5 0.2 4.9 1 1 4 5 5 5 4 Shiga-like toxin beta subunit DUF5592 PF17332.2 EKX31083.1 - 0.2 12.2 11.6 1.5 9.4 1.8 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5592) DUF1736 PF08409.11 EKX31083.1 - 0.68 10.0 22.4 6.2 6.9 0.7 4.6 1 1 4 5 5 5 0 Domain of unknown function (DUF1736) Nab2 PF11517.8 EKX31083.1 - 0.89 9.9 8.7 1e+02 3.3 0.1 4.4 1 1 4 5 5 5 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) DUF3435 PF11917.8 EKX31083.1 - 1.6 7.6 4.2 12 4.7 0.5 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3435) Porin_7 PF16956.5 EKX31084.1 - 0.00072 19.3 0.3 0.00082 19.1 0.3 1.1 1 0 0 1 1 1 1 Putative general bacterial porin GST_C PF00043.25 EKX31084.1 - 2.6 8.3 6.9 30 4.9 2.8 2.9 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain Ank_4 PF13637.6 EKX31085.1 - 1.7e-12 47.6 0.0 1.2e-08 35.3 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX31085.1 - 1.6e-10 41.4 0.0 4.1e-10 40.1 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX31085.1 - 2e-07 31.2 0.2 0.002 18.4 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX31085.1 - 5.1e-06 26.4 0.0 0.15 12.7 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ins_beta PF03488.14 EKX31085.1 - 0.0045 17.0 2.0 2.3 8.3 0.1 3.2 3 0 0 3 3 3 2 Nematode insulin-related peptide beta type Ank PF00023.30 EKX31085.1 - 0.0052 17.2 0.0 2.2 8.9 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat GFRP PF06399.13 EKX31085.1 - 0.052 13.4 0.1 5.7 6.9 0.0 2.3 1 1 1 2 2 2 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) VHS PF00790.19 EKX31085.1 - 0.094 12.6 0.2 9.4 6.1 0.0 2.4 2 1 0 2 2 2 0 VHS domain Glycos_transf_2 PF00535.26 EKX31086.1 - 1e-13 51.4 0.0 3.1e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_25 PF01755.17 EKX31086.1 - 1.4e-07 31.6 0.0 3.8e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_tranf_2_3 PF13641.6 EKX31086.1 - 3.8e-07 30.2 0.0 8.3e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EKX31086.1 - 0.013 16.0 0.0 0.055 14.0 0.0 2.2 1 0 0 1 1 1 0 Glycosyl transferase family 2 IQ PF00612.27 EKX31087.1 - 5.3e-05 22.6 3.4 0.0021 17.7 0.1 2.5 2 0 0 2 2 2 2 IQ calmodulin-binding motif DUF305 PF03713.13 EKX31087.1 - 0.033 14.3 1.4 0.042 14.0 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF305) NOP5NT PF08156.13 EKX31087.1 - 0.045 14.2 1.6 0.13 12.7 0.0 2.3 3 0 0 3 3 3 0 NOP5NT (NUC127) domain PhyH PF05721.13 EKX31087.1 - 0.064 13.5 0.3 0.072 13.3 0.3 1.1 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) PAS_9 PF13426.7 EKX31089.1 - 4.3e-07 30.1 0.0 9.8e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EKX31089.1 - 0.00018 21.5 0.2 0.00062 19.7 0.0 1.9 2 0 0 2 2 2 1 PAS fold DUF3446 PF11928.8 EKX31089.1 - 0.4 11.0 11.3 3.2 8.1 4.1 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain PAS_9 PF13426.7 EKX31090.1 - 4.6e-06 26.8 0.0 0.058 13.6 0.0 3.6 3 1 1 4 4 4 2 PAS domain PAS_4 PF08448.10 EKX31090.1 - 0.00063 20.0 0.0 0.35 11.1 0.0 3.2 3 0 0 3 3 3 1 PAS fold CBM_19 PF03427.13 EKX31091.1 - 0.49 10.4 14.4 0.59 10.2 4.4 3.2 1 1 2 3 3 3 0 Carbohydrate binding domain (family 19) Zn_Tnp_IS1595 PF12760.7 EKX31091.1 - 6.5 6.8 31.8 0.71 9.9 9.3 3.5 1 1 1 3 3 3 0 Transposase zinc-ribbon domain Pkinase PF00069.25 EKX31092.1 - 2.3e-19 69.8 0.0 2.7e-19 69.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX31092.1 - 0.09 12.0 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Pro-MCH PF05824.12 EKX31092.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Pro-melanin-concentrating hormone (Pro-MCH) Med21 PF11221.8 EKX31095.1 - 0.00039 20.7 0.3 0.00039 20.7 0.3 1.3 2 0 0 2 2 2 1 Subunit 21 of Mediator complex RPT PF13446.6 EKX31095.1 - 0.053 13.5 0.1 0.085 12.8 0.1 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein SBBP PF06739.11 EKX31097.1 - 0.031 14.3 0.2 0.23 11.5 0.0 7.3 8 0 0 8 8 8 0 Beta-propeller repeat VP_N-CPKC PF11475.8 EKX31097.1 - 1.1 9.3 7.1 93 3.1 0.2 4.7 3 0 0 3 3 3 0 Virion protein N terminal domain Big_1 PF02369.16 EKX31097.1 - 3.8 7.6 21.4 14 5.8 2.2 4.0 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 1) EF-hand_6 PF13405.6 EKX31098.1 - 3.6e-12 45.2 0.4 0.045 13.7 0.0 6.2 6 0 0 6 6 6 4 EF-hand domain Trypsin PF00089.26 EKX31098.1 - 1.5e-10 41.2 0.6 2.9e-10 40.4 0.6 1.4 1 0 0 1 1 1 1 Trypsin EF-hand_7 PF13499.6 EKX31098.1 - 6.1e-09 36.2 0.4 0.038 14.4 0.0 4.9 4 2 1 5 5 5 4 EF-hand domain pair EF-hand_8 PF13833.6 EKX31098.1 - 8.8e-08 31.9 0.1 0.36 10.7 0.0 4.4 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 EKX31098.1 - 1.9e-06 27.1 14.8 0.012 15.1 0.0 5.4 6 0 0 6 6 6 3 EF hand EF-hand_1 PF00036.32 EKX31098.1 - 2.5e-06 26.6 15.2 0.091 12.4 0.0 6.4 7 0 0 7 7 7 3 EF hand Notch PF00066.17 EKX31098.1 - 0.38 11.3 11.7 0.11 13.0 5.9 3.2 2 0 0 2 2 2 0 LNR domain Chloroa_b-bind PF00504.21 EKX31099.1 - 3.1e-29 102.6 0.0 4.4e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein LRR_6 PF13516.6 EKX31100.1 - 4.3e-48 157.3 38.4 2.1e-05 24.2 0.1 12.5 13 0 0 13 13 13 11 Leucine Rich repeat LRR_4 PF12799.7 EKX31100.1 - 7.1e-12 45.3 24.8 0.00033 21.0 0.8 7.8 4 1 6 10 10 10 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX31100.1 - 1.2e-11 43.4 6.7 8 7.4 0.0 10.1 10 1 0 10 10 10 2 Leucine Rich Repeat LRR_8 PF13855.6 EKX31100.1 - 2.7e-07 30.3 35.6 0.0061 16.3 0.9 9.1 5 4 3 8 8 8 6 Leucine rich repeat LRR_2 PF07723.13 EKX31100.1 - 0.0038 17.8 6.1 30 5.5 0.0 6.7 9 0 0 9 9 9 1 Leucine Rich Repeat NOT2_3_5 PF04153.18 EKX31101.1 - 0.00032 20.8 1.7 0.00076 19.6 1.7 1.6 1 1 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2971 PF11185.8 EKX31104.1 - 0.015 16.4 0.1 0.028 15.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2971) Pox_A11 PF05061.13 EKX31104.1 - 0.04 13.2 0.0 0.045 13.0 0.0 1.0 1 0 0 1 1 1 0 Poxvirus A11 Protein CDC24_OB1 PF17246.2 EKX31104.1 - 1.9 8.6 5.1 0.25 11.4 0.8 1.6 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 1 IBR PF01485.21 EKX31106.1 - 6.1e-08 32.8 10.9 6.1e-08 32.8 10.9 4.7 2 1 1 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EKX31106.1 - 0.0011 19.2 6.4 0.0011 19.2 6.4 4.6 4 0 0 4 4 4 1 Ring finger domain zf-HC5HC2H PF13771.6 EKX31106.1 - 3 8.2 27.8 0.3 11.4 2.5 3.8 3 0 0 3 3 3 0 PHD-like zinc-binding domain IBR PF01485.21 EKX31107.1 - 5e-08 33.0 10.9 5e-08 33.0 10.9 4.9 4 2 0 4 4 4 2 IBR domain, a half RING-finger domain PHD PF00628.29 EKX31107.1 - 0.013 15.3 3.4 0.013 15.3 3.4 4.3 3 0 0 3 3 3 0 PHD-finger IBR PF01485.21 EKX31108.1 - 3.5e-08 33.6 11.0 3.5e-08 33.6 11.0 4.7 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EKX31108.1 - 0.00086 19.6 6.1 0.00086 19.6 6.1 4.7 4 0 0 4 4 4 1 Ring finger domain zf-HC5HC2H PF13771.6 EKX31108.1 - 1.7 8.9 26.9 0.44 10.8 3.2 3.8 3 0 0 3 3 3 0 PHD-like zinc-binding domain Na_H_Exchanger PF00999.21 EKX31111.1 - 1.7e-41 142.3 25.5 2.6e-41 141.7 25.5 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family BSP_II PF05432.11 EKX31112.1 - 0.0043 16.8 9.3 0.0052 16.5 9.3 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) FAD_binding_4 PF01565.23 EKX31113.1 - 3.7e-22 78.5 0.0 2.4e-21 76.0 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain MAS20 PF02064.15 EKX31113.1 - 0.13 12.4 0.9 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 MAS20 protein import receptor Metallophos PF00149.28 EKX31114.1 - 4.5e-09 37.1 0.9 1e-08 35.9 0.9 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Asp PF00026.23 EKX31116.1 - 2.4e-18 66.7 0.0 3.7e-17 62.7 0.0 2.2 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Metallophos PF00149.28 EKX31117.1 - 0.0063 17.0 0.0 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Methyltransf_25 PF13649.6 EKX31119.1 - 1.4e-11 45.0 0.1 2.7e-11 44.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX31119.1 - 1.6e-10 41.5 0.0 3e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EKX31119.1 - 4.2e-10 39.5 0.2 6.4e-10 38.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EKX31119.1 - 1.5e-08 34.6 0.0 2.2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EKX31119.1 - 1.7e-06 27.6 0.1 2.5e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 EKX31119.1 - 1.4e-05 25.1 0.2 2.3e-05 24.4 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX31119.1 - 1.5e-05 24.9 0.0 2.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EKX31119.1 - 2.3e-05 24.0 0.2 4.1e-05 23.2 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EKX31119.1 - 5.3e-05 23.9 0.0 0.00011 22.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 EKX31119.1 - 0.001 20.1 0.0 0.0028 18.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX31119.1 - 0.0031 16.9 0.1 0.0044 16.4 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 EKX31119.1 - 0.011 14.6 0.0 0.015 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.9 EKX31119.1 - 0.044 13.5 0.1 0.069 12.9 0.1 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PRMT5 PF05185.16 EKX31119.1 - 0.063 13.1 0.4 0.15 11.9 0.4 1.5 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_15 PF09445.10 EKX31119.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase IP_trans PF02121.18 EKX31120.1 - 1.2e-91 306.7 0.1 1.5e-91 306.4 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein RabGAP-TBC PF00566.18 EKX31121.1 - 1.5e-25 90.2 0.0 2.4e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CENP-F_leu_zip PF10473.9 EKX31122.1 - 0.016 15.2 0.5 0.02 14.9 0.5 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nup54 PF13874.6 EKX31122.1 - 0.024 14.7 0.3 0.031 14.4 0.3 1.1 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Ada3 PF10198.9 EKX31122.1 - 0.067 13.3 2.7 0.77 9.9 2.6 2.0 1 1 1 2 2 2 0 Histone acetyltransferases subunit 3 Glycoprotein_B PF00606.18 EKX31122.1 - 0.089 12.2 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B ectodomain CCDC-167 PF15188.6 EKX31123.1 - 0.56 10.6 29.6 0.054 13.8 13.7 3.5 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 LMBR1 PF04791.16 EKX31123.1 - 7.9 5.3 12.8 11 4.8 12.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CagA PF03507.13 EKX31124.1 - 0.021 14.7 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 CagA exotoxin Intron_maturas2 PF01348.21 EKX31124.1 - 0.12 12.4 0.2 0.33 10.9 0.2 1.7 1 0 0 1 1 1 0 Type II intron maturase s48_45 PF07422.13 EKX31125.1 - 0.18 12.4 1.8 2.9 8.5 0.4 3.0 2 2 0 2 2 2 0 Sexual stage antigen s48/45 domain Pkinase PF00069.25 EKX31126.1 - 3e-36 125.1 0.0 1.6e-23 83.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EKX31126.1 - 4.6e-17 62.2 0.0 2.6e-13 49.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX31126.1 - 0.0037 16.1 0.0 0.0073 15.1 0.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX31126.1 - 0.0065 16.4 0.0 0.0095 15.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX31126.1 - 0.017 14.5 0.1 0.029 13.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EKX31126.1 - 0.049 13.3 0.1 0.37 10.4 0.0 2.3 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 EKX31126.1 - 0.11 12.0 0.1 0.48 10.0 0.1 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase Presenilin PF01080.17 EKX31129.1 - 0.31 9.8 3.6 0.34 9.6 3.6 1.0 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 EKX31129.1 - 0.56 8.3 3.4 0.59 8.2 3.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nse4_C PF08743.10 EKX31129.1 - 1.1 9.5 3.0 17 5.8 0.9 2.1 2 0 0 2 2 2 0 Nse4 C-terminal DUF3682 PF12446.8 EKX31129.1 - 2 8.9 9.0 4 7.9 9.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Peptidase_M3 PF01432.20 EKX31130.1 - 2.1e-35 122.9 0.2 3.7e-35 122.1 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M3 Pox_A_type_inc PF04508.12 EKX31130.1 - 0.057 13.3 0.9 0.24 11.3 0.9 2.1 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat PKcGMP_CC PF16808.5 EKX31130.1 - 0.84 9.5 7.1 0.2 11.5 0.5 3.2 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FliT PF05400.13 EKX31130.1 - 1.8 9.4 10.1 0.33 11.8 0.8 3.5 3 1 0 3 3 3 0 Flagellar protein FliT Mpv17_PMP22 PF04117.12 EKX31133.1 - 1.6e-06 28.2 0.9 3.7e-06 27.1 0.9 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family Phenol_MetA_deg PF13557.6 EKX31133.1 - 0.047 13.7 0.2 0.067 13.1 0.2 1.2 1 0 0 1 1 1 0 Putative MetA-pathway of phenol degradation DUF4711 PF15829.5 EKX31133.1 - 0.17 11.8 0.2 0.25 11.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) TFIIIC_sub6 PF10419.9 EKX31134.1 - 9.9e-13 47.8 0.0 1.3e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain Pkinase PF00069.25 EKX31135.1 - 7.5e-13 48.4 0.0 8.4e-13 48.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX31135.1 - 2.3e-08 33.6 0.0 2.6e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX31135.1 - 0.00016 21.1 0.0 0.00018 20.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like OCRE PF17780.1 EKX31136.1 - 0.0082 16.2 0.1 0.015 15.4 0.1 1.4 1 0 0 1 1 1 1 OCRE domain Myb_DNA-binding PF00249.31 EKX31137.1 - 2e-05 24.7 0.1 0.00014 22.0 0.1 2.1 1 1 0 1 1 1 1 Myb-like DNA-binding domain HscB_4_cys PF18256.1 EKX31137.1 - 0.0042 16.9 0.3 0.015 15.1 0.3 1.9 1 0 0 1 1 1 1 Co-chaperone HscB tetracysteine metal binding motif Myb_DNA-binding PF00249.31 EKX31139.1 - 2.6e-05 24.3 0.1 0.00017 21.7 0.1 2.0 1 1 0 1 1 1 1 Myb-like DNA-binding domain Ephrin_rec_like PF07699.13 EKX31140.1 - 9e-33 111.8 61.8 6.4e-10 38.6 9.8 5.8 2 2 4 6 6 6 6 Putative ephrin-receptor like NCD3G PF07562.14 EKX31140.1 - 2.9e-11 43.1 42.5 0.0037 17.2 6.4 6.1 2 2 1 5 5 5 5 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX31140.1 - 2e-07 31.3 43.5 0.043 14.2 0.9 8.5 2 2 7 9 9 9 9 TNFR/NGFR cysteine-rich region VSP PF03302.13 EKX31140.1 - 0.00033 19.6 44.4 0.052 12.4 10.0 3.8 1 1 4 5 5 5 5 Giardia variant-specific surface protein Laminin_EGF PF00053.24 EKX31140.1 - 0.16 12.1 49.6 1.8 8.7 7.3 6.7 1 1 3 4 4 4 0 Laminin EGF domain DUF2318 PF10080.9 EKX31140.1 - 4.3 7.5 33.1 1.7 8.8 3.4 4.5 1 1 2 4 4 4 0 Predicted membrane protein (DUF2318) Trans_reg_C PF00486.28 EKX31141.1 - 0.071 13.2 0.2 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal Myb_DNA-binding PF00249.31 EKX31142.1 - 2.5e-05 24.4 0.1 0.00018 21.6 0.1 2.1 1 1 0 1 1 1 1 Myb-like DNA-binding domain Collagen PF01391.18 EKX31144.1 - 2.3e-07 30.5 16.7 5.3e-07 29.3 16.7 1.6 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) IL11 PF07400.11 EKX31144.1 - 0.061 13.0 0.4 0.11 12.2 0.4 1.3 1 0 0 1 1 1 0 Interleukin 11 UBA PF00627.31 EKX31145.1 - 1.1e-25 89.1 10.5 1.4e-14 53.6 0.6 3.3 3 0 0 3 3 3 2 UBA/TS-N domain XPC-binding PF09280.11 EKX31145.1 - 7.3e-22 76.9 7.3 7.3e-22 76.9 7.3 2.1 2 0 0 2 2 2 1 XPC-binding domain ubiquitin PF00240.23 EKX31145.1 - 3.4e-11 42.7 0.0 5.5e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 EKX31145.1 - 0.0064 16.6 0.0 0.04 14.0 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 EKX31145.1 - 0.028 14.3 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 EKX31145.1 - 0.03 14.1 0.0 0.24 11.2 0.0 2.2 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain DUF3306 PF11748.8 EKX31145.1 - 0.65 10.9 7.3 1.2 10.0 5.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) PDZ_6 PF17820.1 EKX31146.1 - 4.7e-06 26.3 0.0 9e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX31146.1 - 0.0012 19.1 0.0 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX31146.1 - 0.0048 17.2 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Beta_helix PF13229.6 EKX31148.1 - 7.8e-32 110.3 30.8 2.1e-13 50.4 7.9 3.2 1 1 2 3 3 3 3 Right handed beta helix region NosD PF05048.13 EKX31148.1 - 3.4e-24 85.4 19.4 5.3e-10 39.0 6.9 3.2 1 1 2 3 3 3 3 Periplasmic copper-binding protein (NosD) Pkinase PF00069.25 EKX31148.1 - 5.3e-18 65.3 0.0 8.2e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX31148.1 - 2.3e-09 36.9 0.0 4e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1565 PF07602.11 EKX31148.1 - 5.3e-05 22.7 14.0 0.12 11.6 6.8 3.6 2 1 1 3 3 3 2 Protein of unknown function (DUF1565) PDZ_6 PF17820.1 EKX31148.1 - 0.0015 18.4 0.2 0.0038 17.1 0.2 1.7 1 0 0 1 1 1 1 PDZ domain DUF4503 PF14951.6 EKX31148.1 - 0.058 11.8 3.6 0.095 11.1 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) PDZ PF00595.24 EKX31148.1 - 0.066 13.6 0.1 0.29 11.5 0.1 2.2 1 0 0 1 1 1 0 PDZ domain Ephrin_rec_like PF07699.13 EKX31149.1 - 6.7e-40 134.6 81.9 1.9e-11 43.5 6.3 9.3 6 2 3 9 9 9 8 Putative ephrin-receptor like NCD3G PF07562.14 EKX31149.1 - 1.1e-12 47.7 63.9 0.00093 19.1 1.9 8.4 5 3 3 8 8 8 8 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX31149.1 - 2.3e-05 24.7 59.7 1 9.9 0.5 9.7 5 3 3 8 8 8 5 TNFR/NGFR cysteine-rich region Phage_tail_NK PF16532.5 EKX31149.1 - 0.0077 15.9 0.4 1.7 8.2 0.2 2.4 2 0 0 2 2 2 2 Sf6-type phage tail needle knob or tip of some Caudovirales YL1_C PF08265.11 EKX31149.1 - 0.017 14.9 0.2 9.9 6.0 0.0 2.8 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain SnAC PF14619.6 EKX31150.1 - 0.00011 22.7 3.9 0.21 12.2 0.3 2.3 1 1 1 2 2 2 2 Snf2-ATP coupling, chromatin remodelling complex Ivy PF08816.11 EKX31150.1 - 0.079 13.2 0.1 17 5.6 0.0 2.2 2 0 0 2 2 2 0 Inhibitor of vertebrate lysozyme (Ivy) SNURF PF07192.11 EKX31150.1 - 0.084 12.7 0.1 18 5.2 0.0 2.2 2 0 0 2 2 2 0 SNURF/RPN4 protein Ntox1 PF15500.6 EKX31150.1 - 0.13 12.6 0.1 24 5.4 0.0 2.2 1 1 1 2 2 2 0 Putative RNase-like toxin, toxin_1 RSB_motif PF16294.5 EKX31150.1 - 0.85 9.9 6.5 7.3 6.9 0.3 3.0 1 1 2 3 3 3 0 RNSP1-SAP18 binding (RSB) motif CS PF04969.16 EKX31151.1 - 7.5e-07 30.1 0.0 1.5e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.6 EKX31151.1 - 3.2e-05 23.8 0.1 5.6e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. polyprenyl_synt PF00348.17 EKX31152.1 - 4e-71 239.1 0.0 5.2e-71 238.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 EKX31152.1 - 2e-05 24.3 0.2 3.2e-05 23.7 0.2 1.2 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 HET PF06985.11 EKX31153.1 - 0.0014 19.0 0.8 0.075 13.4 0.0 2.8 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) PPR_2 PF13041.6 EKX31154.1 - 3.5e-18 65.5 6.3 3.7e-09 36.6 0.3 4.2 3 1 1 4 4 4 3 PPR repeat family PPR_3 PF13812.6 EKX31154.1 - 5.9e-13 48.7 1.8 4.3e-05 23.5 0.1 3.2 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.20 EKX31154.1 - 3.8e-11 42.5 8.5 0.0006 19.9 0.0 5.0 5 0 0 5 5 5 3 PPR repeat PPR_long PF17177.4 EKX31154.1 - 3.3e-09 36.4 0.0 5.4e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EKX31154.1 - 8.7e-07 28.5 4.0 0.088 12.5 0.1 4.1 4 1 0 4 4 4 3 PPR repeat DUF3368 PF11848.8 EKX31154.1 - 0.065 13.0 0.0 20 5.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) PH PF00169.29 EKX31156.1 - 0.0013 19.3 0.0 0.0021 18.5 0.0 1.5 1 0 0 1 1 1 1 PH domain Ribosomal_L26 PF16906.5 EKX31157.1 - 9.3e-38 128.6 2.4 1.2e-37 128.2 2.4 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal Serpin PF00079.20 EKX31160.1 - 4.8e-75 253.2 0.0 5.4e-75 253.0 0.0 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Peroxin-22 PF12827.7 EKX31161.1 - 0.022 14.7 0.0 0.035 14.0 0.0 1.4 1 1 0 1 1 1 0 Peroxisomal biogenesis protein family K_channel_TID PF07941.11 EKX31161.1 - 0.061 13.8 2.3 4.2 7.9 0.2 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain TFIIF_beta_N PF17683.1 EKX31161.1 - 0.16 12.7 0.0 0.27 11.9 0.0 1.3 1 1 0 1 1 1 0 TFIIF, beta subunit N-terminus SET PF00856.28 EKX31162.1 - 0.00076 19.9 10.8 0.0013 19.2 6.5 2.7 2 1 0 2 2 2 1 SET domain DUF913 PF06025.12 EKX31162.1 - 0.86 8.5 5.9 1.3 7.9 4.3 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 EKX31162.1 - 4.1 6.1 4.1 4.9 5.8 4.1 1.1 1 0 0 1 1 1 0 Presenilin Ank_2 PF12796.7 EKX31164.1 - 4.4e-18 65.6 0.1 4.9e-15 55.9 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX31164.1 - 7.7e-18 64.6 0.7 4.3e-08 33.5 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX31164.1 - 1.3e-14 54.0 0.3 5.3e-10 39.4 0.0 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX31164.1 - 8.5e-10 38.0 0.0 0.00013 22.1 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EKX31164.1 - 9.7e-10 38.5 0.0 0.00047 20.5 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Mito_fiss_reg PF05308.11 EKX31164.1 - 0.038 14.1 0.1 0.056 13.5 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EKX31164.1 - 0.044 13.3 2.5 0.041 13.4 1.5 1.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Caskin-Pro-rich PF16907.5 EKX31164.1 - 0.082 13.4 3.3 0.14 12.6 3.3 1.3 1 0 0 1 1 1 0 Proline rich region of Caskin proteins PRIMA1 PF16101.5 EKX31164.1 - 0.13 12.3 2.3 0.23 11.5 2.3 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 HSP90 PF00183.18 EKX31165.1 - 4.8e-62 210.5 15.7 7.2e-55 186.9 3.7 3.7 2 1 2 4 4 4 3 Hsp90 protein HATPase_c_3 PF13589.6 EKX31165.1 - 4.6e-13 49.2 0.2 1.3e-12 47.7 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EKX31165.1 - 5.4e-07 30.1 0.1 1e-06 29.3 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toxin_YhaV PF11663.8 EKX31165.1 - 0.041 13.9 0.0 0.091 12.8 0.0 1.5 1 0 0 1 1 1 0 Toxin with endonuclease activity, of toxin-antitoxin system DUF5356 PF17309.2 EKX31166.1 - 0.0044 17.0 0.2 0.0068 16.4 0.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5356) PDZ_6 PF17820.1 EKX31168.1 - 5.3e-05 23.0 0.0 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX31168.1 - 9.4e-05 22.7 0.0 0.00016 21.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX31168.1 - 0.00034 20.9 0.1 0.00084 19.6 0.1 1.7 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX31168.1 - 0.0038 17.2 0.1 0.0079 16.1 0.1 1.5 1 0 0 1 1 1 1 Tricorn protease PDZ domain DUF3292 PF11696.8 EKX31169.1 - 0.2 10.0 4.2 0.25 9.7 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) RPN2_C PF18004.1 EKX31169.1 - 0.42 10.5 7.6 0.6 10.0 7.6 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CAF1A PF12253.8 EKX31169.1 - 0.94 9.7 0.0 0.94 9.7 0.0 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A Peptidase_S64 PF08192.11 EKX31170.1 - 2.1 6.7 11.5 2.5 6.5 11.5 1.3 1 0 0 1 1 1 0 Peptidase family S64 Menin PF05053.13 EKX31170.1 - 9.5 4.4 22.0 14 3.9 22.0 1.2 1 0 0 1 1 1 0 Menin Mod_r PF07200.13 EKX31171.1 - 0.0063 16.6 1.7 0.0063 16.6 1.7 1.8 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein UPF0242 PF06785.11 EKX31171.1 - 0.035 14.2 1.1 0.035 14.2 1.1 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF641 PF04859.12 EKX31171.1 - 0.055 13.8 4.2 1.3 9.4 4.2 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) PKcGMP_CC PF16808.5 EKX31171.1 - 0.081 12.8 9.6 0.57 10.1 1.1 2.9 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase KLRAQ PF10205.9 EKX31171.1 - 0.88 9.9 6.6 0.16 12.3 1.0 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Serglycin PF04360.12 EKX31172.1 - 0.31 11.0 11.9 0.62 10.0 11.9 1.4 1 0 0 1 1 1 0 Serglycin Glyco_tran_28_C PF04101.16 EKX31174.1 - 5.8e-14 52.4 0.0 1e-13 51.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain MGDG_synth PF06925.11 EKX31174.1 - 2.7e-12 47.1 0.0 4.7e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_trans_1_4 PF13692.6 EKX31174.1 - 4.5e-07 30.4 0.0 1.1e-06 29.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EKX31174.1 - 4.7e-06 26.3 0.0 8.6e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Epimerase_2 PF02350.19 EKX31174.1 - 0.0019 17.1 0.0 0.0032 16.4 0.0 1.3 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase DUF5042 PF16445.5 EKX31174.1 - 0.18 10.2 0.0 0.24 9.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5042) ABC_membrane PF00664.23 EKX31177.1 - 1.9e-20 73.7 9.5 5.5e-14 52.5 1.4 2.2 1 1 1 2 2 2 2 ABC transporter transmembrane region Pneumo_att_G PF05539.11 EKX31177.1 - 0.076 12.6 0.1 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G SUIM_assoc PF16619.5 EKX31178.1 - 0.036 14.1 10.2 0.79 9.8 6.4 3.5 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Oxidored-like PF09791.9 EKX31178.1 - 0.074 12.7 0.2 0.14 11.9 0.2 1.4 1 0 0 1 1 1 0 Oxidoreductase-like protein, N-terminal Androgen_recep PF02166.16 EKX31178.1 - 0.48 9.2 8.5 0.7 8.7 8.5 1.1 1 0 0 1 1 1 0 Androgen receptor Activator_LAG-3 PF11498.8 EKX31178.1 - 5 6.0 23.2 8.1 5.3 23.2 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 AAA_18 PF13238.6 EKX31179.1 - 1.2e-05 25.8 0.3 0.00014 22.4 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 EKX31179.1 - 2.4e-05 24.5 0.0 3.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EKX31179.1 - 0.0022 18.3 0.0 0.0056 16.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain CoaE PF01121.20 EKX31179.1 - 0.025 14.3 0.0 0.057 13.1 0.0 1.6 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_5 PF07728.14 EKX31179.1 - 0.048 13.6 0.4 0.18 11.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Ploopntkinase3 PF18751.1 EKX31179.1 - 0.069 13.1 0.0 0.099 12.5 0.0 1.2 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_16 PF13191.6 EKX31179.1 - 0.073 13.5 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 EKX31179.1 - 0.15 12.3 3.6 0.18 12.0 0.3 2.3 2 1 0 2 2 2 0 AAA domain Cofilin_ADF PF00241.20 EKX31180.1 - 2.7e-19 69.1 0.0 3.5e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF3299 PF11736.8 EKX31183.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3299) Rdx PF10262.9 EKX31184.1 - 0.0049 17.0 0.1 0.014 15.5 0.1 1.7 1 0 0 1 1 1 1 Rdx family CarboxypepD_reg PF13620.6 EKX31184.1 - 0.067 13.5 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain AAA_14 PF13173.6 EKX31185.1 - 1.5e-06 28.3 0.0 3.5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EKX31185.1 - 0.00084 19.2 0.0 0.0016 18.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EKX31185.1 - 0.0014 18.4 0.0 0.012 15.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EKX31185.1 - 0.0086 16.6 0.2 0.031 14.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EKX31185.1 - 0.0099 16.3 0.1 0.095 13.1 0.1 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EKX31185.1 - 0.012 16.0 0.0 0.033 14.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 EKX31185.1 - 0.012 15.2 0.1 0.034 13.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EKX31185.1 - 0.013 15.8 0.0 0.043 14.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EKX31185.1 - 0.015 15.7 0.0 0.038 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 EKX31185.1 - 0.025 14.9 0.1 0.11 12.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EKX31185.1 - 0.031 14.8 0.1 0.073 13.6 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 EKX31185.1 - 0.041 13.4 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 EKX31185.1 - 0.052 13.6 0.1 0.22 11.5 0.0 2.1 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 EKX31185.1 - 0.087 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 EKX31185.1 - 0.097 12.4 0.0 0.72 9.5 0.0 2.3 3 0 0 3 3 3 0 AAA domain RsfS PF02410.15 EKX31186.1 - 2.5e-20 72.7 0.5 2.5e-20 72.7 0.5 1.5 2 0 0 2 2 2 1 Ribosomal silencing factor during starvation SeqA PF03925.13 EKX31186.1 - 0.082 12.9 0.0 0.082 12.9 0.0 1.7 2 0 0 2 2 2 0 SeqA protein C-terminal domain BCCT PF02028.17 EKX31187.1 - 6.8e-115 384.3 39.9 5.2e-111 371.5 34.7 2.0 2 0 0 2 2 2 2 BCCT, betaine/carnitine/choline family transporter zf-CCHC PF00098.23 EKX31188.1 - 8.2e-06 25.7 17.1 0.00025 21.0 3.9 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_5 PF14787.6 EKX31188.1 - 5.1e-05 22.9 6.5 5.1e-05 22.9 6.5 2.4 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 EKX31188.1 - 0.38 10.6 10.5 1.7 8.5 1.5 2.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 EKX31188.1 - 9.2 6.1 8.1 15 5.5 1.5 2.3 2 0 0 2 2 2 0 Zinc knuckle ArfGap PF01412.18 EKX31189.1 - 4.7e-22 78.2 1.7 4.9e-22 78.2 1.7 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-LYAR PF08790.11 EKX31189.1 - 0.46 10.4 3.3 6.5 6.8 0.3 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger SAPS PF04499.15 EKX31190.1 - 0.028 13.2 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SH3_15 PF18346.1 EKX31190.1 - 0.25 11.7 2.8 3.4 8.0 0.1 3.3 3 1 0 3 3 3 0 Mind bomb SH3 repeat domain NAM PF02365.15 EKX31191.1 - 0.023 15.6 0.1 0.033 15.1 0.1 1.2 1 0 0 1 1 1 0 No apical meristem (NAM) protein SelR PF01641.18 EKX31192.1 - 1.5e-06 28.3 0.1 3.4e-06 27.1 0.1 1.5 1 1 0 1 1 1 1 SelR domain Arm PF00514.23 EKX31194.1 - 7.8e-20 70.2 2.9 0.0031 17.5 0.0 5.2 5 0 0 5 5 5 5 Armadillo/beta-catenin-like repeat DUF1269 PF06897.12 EKX31194.1 - 1e-05 25.7 19.6 0.68 10.3 0.3 4.2 4 0 0 4 4 4 4 Protein of unknown function (DUF1269) DUF4630 PF15443.6 EKX31194.1 - 1.2e-05 25.6 35.0 0.42 10.8 2.2 5.1 1 1 4 5 5 5 5 Domain of unknown function (DUF4630) HEAT_2 PF13646.6 EKX31194.1 - 6.2e-05 23.3 18.0 0.05 14.0 1.7 3.6 1 1 3 4 4 4 4 HEAT repeats HEAT_EZ PF13513.6 EKX31194.1 - 7.9e-05 23.1 20.0 0.019 15.5 2.3 4.2 2 2 2 4 4 4 3 HEAT-like repeat HEAT PF02985.22 EKX31194.1 - 0.00027 20.9 7.4 24 5.5 0.1 5.3 5 0 0 5 5 5 0 HEAT repeat Gly-zipper_Omp PF13488.6 EKX31194.1 - 0.00072 19.5 20.8 1.8 8.6 0.1 4.3 4 0 0 4 4 4 4 Glycine zipper Rick_17kDa_Anti PF05433.15 EKX31194.1 - 0.0039 17.0 18.6 5.2 7.0 0.5 4.4 4 0 0 4 4 4 4 Glycine zipper 2TM domain T2SSF PF00482.23 EKX31194.1 - 0.013 15.4 6.5 10 6.1 0.3 4.2 1 1 1 4 4 4 0 Type II secretion system (T2SS), protein F Atx10homo_assoc PF09759.9 EKX31194.1 - 0.059 13.4 0.0 22 5.1 0.0 2.5 1 1 3 4 4 4 0 Spinocerebellar ataxia type 10 protein domain ALF PF03752.13 EKX31194.1 - 0.44 10.6 22.2 14 5.7 0.2 5.3 5 0 0 5 5 5 0 Short repeats of unknown function FtsK_4TM PF13491.6 EKX31194.1 - 2.7 7.6 5.5 1.6e+02 1.9 0.1 3.7 4 0 0 4 4 4 0 4TM region of DNA translocase FtsK/SpoIIIE PBP3 PF18056.1 EKX31194.1 - 3.2 7.9 9.6 65 3.7 0.1 3.9 1 1 3 4 4 4 0 Penicillin Binding Protein 3 Domain Pkinase_Tyr PF07714.17 EKX31195.1 - 2.3e-43 148.3 0.0 2.6e-43 148.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX31195.1 - 6.7e-24 84.7 0.0 6.7e-24 84.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EKX31195.1 - 0.0084 14.9 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EKX31195.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family U-box PF04564.15 EKX31196.1 - 4.5e-18 65.2 0.0 5.3e-18 65.0 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX31196.1 - 3.1e-06 26.9 0.0 3.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EKX31196.1 - 0.00014 21.8 0.0 0.0002 21.3 0.0 1.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-NOSIP PF15906.5 EKX31196.1 - 0.011 15.9 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_2 PF13923.6 EKX31196.1 - 0.019 14.8 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SH3_1 PF00018.28 EKX31198.1 - 4.9e-06 26.1 0.0 1.6e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EKX31198.1 - 8.2e-06 25.6 0.1 1.9e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EKX31198.1 - 0.00019 21.1 1.4 0.00052 19.6 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain Ank_2 PF12796.7 EKX31199.1 - 4e-23 81.8 0.7 1.2e-12 48.3 0.0 3.7 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EKX31199.1 - 1.9e-22 78.6 0.2 1.2e-05 25.6 0.1 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 EKX31199.1 - 3.8e-16 59.2 4.3 0.00016 22.1 0.0 5.6 4 1 3 7 7 7 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX31199.1 - 1.2e-15 57.3 2.8 8.8e-05 22.7 0.1 5.3 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX31199.1 - 8.5e-13 47.3 3.2 0.046 14.3 0.0 6.5 5 2 0 5 5 5 3 Ankyrin repeat Selenoprotein_S PF06936.11 EKX31199.1 - 0.4 10.5 1.9 0.66 9.8 1.9 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) Ank_5 PF13857.6 EKX31200.1 - 1.5e-13 50.7 0.2 2.8e-13 49.8 0.2 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX31200.1 - 2.8e-11 43.8 0.1 9.5e-09 35.7 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EKX31200.1 - 6.9e-11 42.1 0.3 6.2e-08 32.7 0.4 3.4 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 EKX31200.1 - 4.8e-10 39.8 0.1 8.7e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX31200.1 - 4.7e-08 32.7 0.1 2.8e-05 24.1 0.1 4.0 5 0 0 5 5 5 1 Ankyrin repeat FAM183 PF14886.6 EKX31201.1 - 0.17 12.6 0.0 0.24 12.2 0.0 1.3 1 0 0 1 1 1 0 FAM183A and FAM183B related DUF5640 PF18692.1 EKX31202.1 - 4.3e-05 23.5 6.0 0.27 11.3 0.1 3.8 1 1 5 6 6 6 5 Family of unknown function (DUF5640) TraY PF05509.11 EKX31202.1 - 0.038 14.0 21.4 11 6.2 0.2 6.9 4 2 3 7 7 7 0 TraY domain PINIT PF14324.6 EKX31202.1 - 0.13 12.6 5.1 3.7 7.9 0.7 3.1 1 1 1 2 2 2 0 PINIT domain DNA_pol_B_3 PF08408.10 EKX31202.1 - 0.26 11.5 2.9 2.7 8.2 0.5 2.7 1 1 1 2 2 2 0 DNA polymerase family B viral insert Fra10Ac1 PF09725.9 EKX31202.1 - 0.33 11.0 8.9 3.2 7.8 0.5 3.2 1 1 1 2 2 2 0 Folate-sensitive fragile site protein Fra10Ac1 DAP_B PF07930.12 EKX31202.1 - 2 8.3 8.7 3.6 7.5 2.8 2.4 1 1 1 2 2 2 0 D-aminopeptidase, domain B Peptidase_C48 PF02902.19 EKX31203.1 - 5.2e-10 39.5 0.0 5.8e-10 39.4 0.0 1.0 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Ank_3 PF13606.6 EKX31204.1 - 2.8e-13 48.7 0.7 1.6 9.5 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.7 EKX31204.1 - 6.4e-12 45.9 1.6 0.0016 19.0 0.0 3.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX31204.1 - 8e-12 45.4 2.3 0.028 15.0 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX31204.1 - 2.1e-07 31.1 5.5 0.15 12.4 0.0 5.7 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX31205.1 - 2e-11 44.2 0.1 2.4e-11 43.9 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX31205.1 - 1.5e-09 38.3 0.2 1.6e-09 38.2 0.2 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX31205.1 - 1.7e-08 34.5 2.9 7.7e-06 26.1 0.4 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EKX31205.1 - 6.3e-05 23.1 0.2 0.13 12.9 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EKX31205.1 - 0.0017 18.7 0.3 0.059 13.7 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) ART PF01129.18 EKX31206.1 - 4.4e-05 22.9 0.0 5.2e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase ADPrib_exo_Tox PF03496.14 EKX31206.1 - 0.0066 15.8 0.0 0.0082 15.5 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosyltransferase exoenzyme TUDOR_5 PF18359.1 EKX31207.1 - 1e-12 47.5 1.3 5.7e-07 29.1 0.0 2.5 2 0 0 2 2 2 2 Histone methyltransferase Tudor domain 1 zf-MIZ PF02891.20 EKX31207.1 - 1.7e-07 30.9 0.1 3.2e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger LBR_tudor PF09465.10 EKX31207.1 - 0.00019 21.2 2.4 0.00036 20.3 0.6 2.4 2 0 0 2 2 2 1 Lamin-B receptor of TUDOR domain Tudor_3 PF18115.1 EKX31207.1 - 0.0029 17.4 0.0 0.55 10.1 0.0 2.7 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 EKX31207.1 - 0.0084 16.1 0.0 0.033 14.2 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Agenet PF05641.12 EKX31207.1 - 0.011 16.1 6.3 0.084 13.4 0.0 4.0 5 0 0 5 5 5 0 Agenet domain 53-BP1_Tudor PF09038.10 EKX31207.1 - 0.028 14.4 0.7 9.7 6.2 0.0 3.0 2 0 0 2 2 2 0 Tumour suppressor p53-binding protein-1 Tudor Tudor-knot PF11717.8 EKX31207.1 - 0.082 12.8 0.4 0.3 11.0 0.1 2.2 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain DUF2967 PF11179.8 EKX31208.1 - 0.16 10.1 4.2 0.23 9.5 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Keratin_2_head PF16208.5 EKX31208.1 - 0.63 10.2 15.9 1.3 9.2 15.9 1.5 1 0 0 1 1 1 0 Keratin type II head TraT PF05818.12 EKX31208.1 - 9.2 5.9 9.6 15 5.2 9.6 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Myb_DNA-binding PF00249.31 EKX31210.1 - 1.4e-05 25.2 0.1 0.00011 22.3 0.1 2.1 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EKX31211.1 - 3.4e-05 23.9 0.1 0.00021 21.4 0.1 2.1 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EKX31212.1 - 2.2e-05 24.6 0.1 0.00015 21.9 0.1 2.1 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EKX31213.1 - 1.6e-05 25.0 0.1 0.00012 22.2 0.1 2.1 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EKX31215.1 - 1.8e-05 24.8 0.1 0.00013 22.0 0.1 2.1 1 1 0 1 1 1 1 Myb-like DNA-binding domain ADH_zinc_N_2 PF13602.6 EKX31216.1 - 2.3e-17 64.3 0.0 8.6e-17 62.4 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EKX31216.1 - 4.8e-11 42.7 0.0 2.2e-10 40.6 0.0 2.1 3 0 0 3 3 3 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EKX31216.1 - 0.03 13.6 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.21 EKX31216.1 - 0.072 12.8 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_N PF08240.12 EKX31216.1 - 0.089 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain LPP PF04728.13 EKX31217.1 - 0.052 13.9 0.8 0.9 10.0 0.1 2.6 3 0 0 3 3 3 0 Lipoprotein leucine-zipper KxDL PF10241.9 EKX31217.1 - 0.069 13.4 1.0 0.31 11.4 1.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein Ank_2 PF12796.7 EKX31218.1 - 8.3e-32 109.6 5.8 1.6e-08 35.0 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX31218.1 - 5.7e-30 103.3 2.3 1e-08 35.5 0.2 5.1 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX31218.1 - 4e-19 66.7 1.4 0.058 14.0 0.0 7.0 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EKX31218.1 - 1.4e-17 63.5 5.4 0.00041 20.6 0.3 5.6 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EKX31218.1 - 1.5e-15 56.9 9.0 0.00044 20.6 0.1 6.2 7 0 0 7 7 7 5 Ankyrin repeat DUF1843 PF08898.10 EKX31218.1 - 0.048 14.2 6.4 0.085 13.4 0.7 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Voldacs PF03517.13 EKX31220.1 - 4e-26 91.8 0.8 5.1e-26 91.4 0.8 1.1 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Vps36_ESCRT-II PF11605.8 EKX31220.1 - 3.7e-08 33.4 0.0 6.1e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 PH_TFIIH PF08567.11 EKX31220.1 - 0.015 15.6 0.0 0.032 14.6 0.0 1.4 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain GRAM PF02893.20 EKX31220.1 - 0.096 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 GRAM domain DUF2451 PF10474.9 EKX31221.1 - 1.1e-11 45.0 0.0 2.5e-05 24.2 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function C-terminus (DUF2451) Ank_2 PF12796.7 EKX31223.1 - 3.2e-10 40.5 0.0 2.3e-06 28.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX31223.1 - 6.5e-10 39.4 0.0 0.00019 21.9 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX31223.1 - 3.5e-05 24.0 0.0 0.31 11.4 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX31223.1 - 0.00044 20.6 0.1 0.19 12.2 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EKX31223.1 - 0.016 15.7 0.0 28 5.7 0.0 3.6 4 0 0 4 4 4 0 Ankyrin repeat Pkinase_Tyr PF07714.17 EKX31224.1 - 2.4e-38 131.9 0.0 2.6e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX31224.1 - 4.2e-15 55.8 0.0 4.7e-15 55.7 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain U-box PF04564.15 EKX31225.1 - 4.2e-17 62.1 0.0 4.9e-17 61.9 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX31225.1 - 2.2e-05 24.2 0.0 3.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EKX31225.1 - 0.00013 21.9 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-NOSIP PF15906.5 EKX31225.1 - 0.0057 16.8 0.0 0.0072 16.4 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Ank_2 PF12796.7 EKX31227.1 - 8.7e-26 90.3 0.0 3.6e-11 43.5 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX31227.1 - 2.5e-24 85.3 0.2 4.3e-07 30.4 0.0 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX31227.1 - 8.6e-20 68.7 0.0 0.032 14.8 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EKX31227.1 - 1.4e-18 66.7 1.4 0.065 13.6 0.0 5.9 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EKX31227.1 - 2e-09 37.4 0.0 4.9 7.8 0.0 6.0 6 0 0 6 6 6 2 Ankyrin repeat Ins_beta PF03488.14 EKX31227.1 - 1.4e-05 24.9 9.8 15 5.6 0.1 6.1 6 0 0 6 6 6 2 Nematode insulin-related peptide beta type TolA_bind_tri PF16331.5 EKX31227.1 - 0.0014 18.6 0.1 21 5.3 0.0 4.4 5 0 0 5 5 5 0 TolA binding protein trimerisation FANCI_S3 PF14677.6 EKX31227.1 - 0.0022 17.7 0.0 5.6 6.6 0.0 3.9 1 1 3 4 4 4 1 FANCI solenoid 3 Herpes_UL33 PF03581.13 EKX31227.1 - 0.0069 16.7 2.3 3.9 7.9 0.1 3.6 3 1 0 3 3 3 1 Herpesvirus UL33-like protein VHS PF00790.19 EKX31227.1 - 0.019 14.8 2.5 39 4.1 0.0 4.5 6 0 0 6 6 6 0 VHS domain CHORD PF04968.12 EKX31227.1 - 0.72 10.6 8.8 50 4.7 0.3 4.7 3 1 2 5 5 5 0 CHORD Helicase_C PF00271.31 EKX31228.1 - 1.5e-14 54.3 0.0 9e-14 51.8 0.0 2.4 3 0 0 3 3 2 1 Helicase conserved C-terminal domain HA2 PF04408.23 EKX31228.1 - 1.6e-10 41.2 0.4 4.6e-10 39.7 0.4 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 EKX31228.1 - 1.3e-09 38.0 0.2 2.7e-09 37.1 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EKX31228.1 - 0.00032 21.0 0.1 0.0027 18.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 EKX31228.1 - 0.00042 20.4 0.1 0.00099 19.1 0.1 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 EKX31228.1 - 0.0012 18.7 0.1 0.0017 18.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EKX31228.1 - 0.0016 19.0 0.4 0.027 15.0 0.4 2.1 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 EKX31228.1 - 0.0019 17.6 0.0 0.0033 16.8 0.0 1.4 1 1 0 1 1 1 1 KaiC ATPase_2 PF01637.18 EKX31228.1 - 0.002 18.1 0.1 0.0038 17.2 0.1 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 EKX31228.1 - 0.025 14.9 0.0 0.061 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 EKX31228.1 - 0.032 14.2 0.2 3.4 7.7 0.1 2.7 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EKX31228.1 - 0.036 14.0 0.0 0.11 12.4 0.0 2.0 1 1 0 1 1 1 0 NACHT domain SMC_N PF02463.19 EKX31228.1 - 0.043 13.3 0.1 0.22 10.9 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_7 PF12775.7 EKX31228.1 - 0.053 13.0 0.3 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 EKX31228.1 - 0.11 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 EKX31228.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EKX31228.1 - 0.12 12.9 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter U-box PF04564.15 EKX31230.1 - 2.2e-19 69.4 0.0 2.6e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX31230.1 - 1.8e-05 24.5 0.0 2.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EKX31230.1 - 0.00018 21.5 0.1 0.00028 20.9 0.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-NOSIP PF15906.5 EKX31230.1 - 0.011 15.9 0.0 0.014 15.5 0.0 1.1 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Pkinase_Tyr PF07714.17 EKX31231.1 - 9.9e-39 133.2 0.0 1.1e-38 133.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX31231.1 - 3.5e-15 56.1 0.0 3.9e-15 55.9 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain Cornifin PF02389.15 EKX31232.1 - 0.00014 22.1 0.1 0.00016 21.8 0.1 1.0 1 0 0 1 1 1 1 Cornifin (SPRR) family GlutR_dimer PF00745.20 EKX31232.1 - 0.00026 21.4 2.2 0.76 10.3 2.2 3.5 1 1 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain Zemlya PF17646.1 EKX31232.1 - 0.01 16.2 0.2 2.8 8.3 0.1 2.2 1 1 1 2 2 2 0 Closterovirus 1a polyprotein central region Cys_rich_FGFR PF00839.17 EKX31232.1 - 0.03 14.5 25.3 1.8e+04 -13.4 25.3 5.7 1 1 0 1 1 1 0 Cysteine rich repeat ADSL_C PF10397.9 EKX31232.1 - 1.3 9.6 7.2 3.9e+02 1.7 7.2 3.1 1 1 0 1 1 1 0 Adenylosuccinate lyase C-terminus Ank_2 PF12796.7 EKX31233.1 - 4.4e-28 97.7 0.8 4.1e-08 33.7 0.0 4.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX31233.1 - 1.6e-23 82.8 0.6 7.1e-07 29.7 0.0 4.8 4 2 0 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX31233.1 - 3.3e-17 62.3 8.6 0.023 15.0 0.0 6.6 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX31233.1 - 6.4e-14 50.7 4.0 0.48 11.1 0.0 7.2 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 EKX31233.1 - 1.6e-10 40.9 7.6 0.88 10.1 0.0 6.8 6 1 1 7 7 7 5 Ankyrin repeat BDHCT PF08072.11 EKX31233.1 - 0.036 14.2 2.4 1.1e+02 3.1 0.1 4.4 4 0 0 4 4 4 0 BDHCT (NUC031) domain Chol_subst-bind PF09129.11 EKX31233.1 - 0.049 12.6 0.0 17 4.2 0.0 3.4 2 2 2 4 4 4 0 Cholesterol oxidase, substrate-binding FANCI_S3 PF14677.6 EKX31233.1 - 0.18 11.5 0.0 0.44 10.2 0.0 1.7 1 1 0 1 1 1 0 FANCI solenoid 3 Ins_beta PF03488.14 EKX31233.1 - 1 9.4 10.6 15 5.7 0.0 5.1 6 0 0 6 6 6 0 Nematode insulin-related peptide beta type DUF550 PF04447.12 EKX31234.1 - 0.00045 20.3 6.4 5.7 7.1 0.1 4.6 5 0 0 5 5 5 3 Protein of unknown function (DUF550) DUF3367 PF11847.8 EKX31235.1 - 0.15 9.9 0.3 0.16 9.9 0.3 1.0 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase TPR_17 PF13431.6 EKX31236.1 - 5.6e-29 98.4 2.3 0.0002 21.5 0.1 10.5 9 1 1 10 10 10 7 Tetratricopeptide repeat TPR_14 PF13428.6 EKX31236.1 - 5.2e-27 92.2 20.8 0.021 15.6 0.0 11.0 3 3 8 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.17 EKX31236.1 - 1.2e-25 87.5 13.8 0.031 14.4 0.0 11.1 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_16 PF13432.6 EKX31236.1 - 6.4e-19 68.3 13.4 0.00013 22.5 1.1 7.8 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 EKX31236.1 - 1.4e-17 62.7 11.9 0.031 14.1 0.1 10.5 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_19 PF14559.6 EKX31236.1 - 8.8e-17 61.4 17.1 0.00082 19.8 0.5 8.3 4 3 3 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 EKX31236.1 - 2.9e-15 55.1 5.9 0.052 13.8 0.0 9.6 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_12 PF13424.6 EKX31236.1 - 2.3e-14 53.4 16.1 5.2e-08 33.1 0.6 7.5 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX31236.1 - 9.4e-13 47.2 8.5 0.081 13.0 0.1 9.1 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX31236.1 - 3.2e-12 45.9 11.8 0.54 10.0 0.3 10.1 7 3 4 11 11 11 2 TPR repeat TPR_10 PF13374.6 EKX31236.1 - 5.2e-08 32.5 24.2 0.001 18.9 0.9 8.9 11 0 0 11 11 10 1 Tetratricopeptide repeat Coatomer_E PF04733.14 EKX31236.1 - 3.5e-06 26.6 3.0 0.5 9.7 0.0 3.8 2 1 2 4 4 4 3 Coatomer epsilon subunit TPR_6 PF13174.6 EKX31236.1 - 1.3e-05 25.5 8.8 0.3 11.8 0.1 7.2 8 1 0 8 8 7 1 Tetratricopeptide repeat TAtT PF16811.5 EKX31236.1 - 6e-05 22.5 0.5 0.24 10.7 0.0 3.4 3 0 0 3 3 3 2 TRAP transporter T-component Tcf25 PF04910.14 EKX31236.1 - 0.00013 21.2 0.8 1.8 7.6 0.1 4.3 2 1 3 5 5 5 1 Transcriptional repressor TCF25 TPR_9 PF13371.6 EKX31236.1 - 0.00046 20.3 15.4 0.18 12.0 0.2 5.6 3 2 3 6 6 6 2 Tetratricopeptide repeat AD PF09793.9 EKX31236.1 - 0.14 12.3 0.3 0.39 10.9 0.3 1.7 1 0 0 1 1 1 0 Anticodon-binding domain MIT PF04212.18 EKX31236.1 - 0.81 9.8 4.0 30 4.8 0.2 3.7 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 EKX31236.1 - 1 9.6 5.9 4.5 7.6 2.3 3.7 4 1 2 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 PET117 PF15786.5 EKX31237.1 - 0.33 11.2 0.0 0.33 11.2 0.0 2.0 3 0 0 3 3 3 0 PET assembly of cytochrome c oxidase, mitochondrial PHD PF00628.29 EKX31238.1 - 2.3e-17 62.6 41.9 4e-09 36.2 10.4 3.4 3 0 0 3 3 3 3 PHD-finger zf-HC5HC2H PF13771.6 EKX31238.1 - 1.4e-06 28.4 40.5 0.12 12.7 9.3 3.4 1 1 2 3 3 3 3 PHD-like zinc-binding domain zf-RING_2 PF13639.6 EKX31238.1 - 8.2e-05 22.9 38.8 0.00039 20.7 8.2 3.4 3 0 0 3 3 3 3 Ring finger domain C1_1 PF00130.22 EKX31238.1 - 0.0013 18.5 9.5 0.0013 18.5 9.5 3.8 1 1 3 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 EKX31238.1 - 0.0053 16.4 30.1 0.033 13.8 2.4 4.0 2 2 1 4 4 4 3 PHD/FYVE-zinc-finger like domain zf-rbx1 PF12678.7 EKX31238.1 - 0.14 12.4 40.3 0.062 13.6 11.3 3.7 2 2 2 4 4 4 0 RING-H2 zinc finger domain FANCL_C PF11793.8 EKX31238.1 - 0.2 11.9 35.8 0.29 11.3 16.7 3.6 1 1 2 3 3 3 0 FANCL C-terminal domain SET PF00856.28 EKX31239.1 - 1.5e-14 54.7 0.1 1.5e-14 54.7 0.1 1.4 2 0 0 2 2 2 1 SET domain Amelin PF05111.12 EKX31239.1 - 0.025 13.7 0.0 0.029 13.5 0.0 1.0 1 0 0 1 1 1 0 Ameloblastin precursor (Amelin) Ephrin_rec_like PF07699.13 EKX31240.1 - 4.6e-10 39.1 103.3 3.2e-06 26.8 5.5 12.0 7 4 4 11 11 11 7 Putative ephrin-receptor like Gemini_BL1 PF00845.19 EKX31241.1 - 0.0046 16.6 0.2 0.21 11.1 0.1 2.0 1 1 1 2 2 2 2 Geminivirus BL1 movement protein Toxin_5 PF05294.13 EKX31241.1 - 0.026 14.9 5.3 0.29 11.6 1.0 2.3 2 0 0 2 2 2 0 Scorpion short toxin PAN_2 PF08276.11 EKX31241.1 - 0.041 14.0 0.8 2 8.6 0.2 2.3 2 0 0 2 2 2 0 PAN-like domain HrpB7 PF09486.10 EKX31241.1 - 3.7 7.9 5.9 3.7 7.9 1.0 2.1 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) zf-CCHC PF00098.23 EKX31242.1 - 2.1e-17 62.3 23.3 1.3e-07 31.3 1.7 3.1 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.6 EKX31242.1 - 9.1e-06 25.5 17.1 0.0091 15.9 3.4 3.1 1 1 2 3 3 3 3 Zinc knuckle zf-CCHC_5 PF14787.6 EKX31242.1 - 1.2e-05 24.9 15.8 0.0092 15.7 1.1 3.1 3 0 0 3 3 3 3 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 EKX31242.1 - 0.00021 21.0 6.1 0.0042 16.9 0.6 3.2 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_4 PF14392.6 EKX31242.1 - 0.0012 18.5 16.2 0.62 9.8 1.5 3.1 3 0 0 3 3 3 3 Zinc knuckle YhfH PF14149.6 EKX31242.1 - 0.081 12.9 0.2 0.081 12.9 0.2 3.1 3 0 0 3 3 3 0 YhfH-like protein DZR PF12773.7 EKX31242.1 - 0.24 11.5 12.2 0.043 13.8 5.9 2.5 2 1 0 2 2 2 0 Double zinc ribbon PHD PF00628.29 EKX31242.1 - 0.74 9.7 11.2 15 5.6 4.3 3.0 1 1 2 3 3 3 0 PHD-finger zf-ribbon_3 PF13248.6 EKX31242.1 - 2.7 7.5 10.9 6 6.4 0.5 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Prok-RING_2 PF14445.6 EKX31242.1 - 3.5 7.9 9.3 1.1 9.5 1.4 2.6 1 1 2 3 3 3 0 Prokaryotic RING finger family 2 Anti-TRAP PF15777.5 EKX31242.1 - 4.8 7.2 7.9 4.7 7.3 2.4 2.4 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF2961 PF11175.8 EKX31243.1 - 0.052 13.2 0.0 0.066 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) Acetyltransf_7 PF13508.7 EKX31245.1 - 0.0001 22.7 0.0 0.00019 21.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EKX31245.1 - 0.046 13.9 0.0 0.06 13.6 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_13 PF13880.6 EKX31245.1 - 0.14 12.2 0.9 1.7 8.6 0.1 2.6 3 0 0 3 3 3 0 ESCO1/2 acetyl-transferase Glyco_tranf_2_3 PF13641.6 EKX31247.1 - 0.0017 18.3 0.2 0.0084 16.0 0.2 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EKX31247.1 - 0.0062 16.4 0.0 0.026 14.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 TFIIA PF03153.13 EKX31248.1 - 4.2e-06 27.0 43.7 7.9e-06 26.1 43.7 1.5 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Lipase_3 PF01764.25 EKX31248.1 - 0.019 14.8 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Otopetrin PF03189.13 EKX31248.1 - 0.041 12.7 5.4 0.052 12.4 5.4 1.3 1 0 0 1 1 1 0 Otopetrin Presenilin PF01080.17 EKX31248.1 - 0.054 12.3 29.9 0.086 11.6 29.9 1.3 1 0 0 1 1 1 0 Presenilin DUF966 PF06136.13 EKX31248.1 - 0.11 12.3 22.9 0.15 11.7 22.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CBP_BcsG PF11658.8 EKX31248.1 - 0.13 10.7 17.4 0.2 10.0 17.4 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG eIF-3_zeta PF05091.12 EKX31248.1 - 0.21 10.5 29.8 0.39 9.6 29.8 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ABC2_membrane_2 PF12679.7 EKX31248.1 - 0.28 10.4 3.1 0.55 9.5 1.1 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein NPR3 PF03666.13 EKX31248.1 - 0.38 9.5 25.7 0.67 8.7 25.7 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Ndc1_Nup PF09531.10 EKX31248.1 - 0.59 8.8 33.3 0.83 8.3 33.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HCO3_cotransp PF00955.21 EKX31248.1 - 0.6 8.9 10.6 0.92 8.3 10.6 1.2 1 0 0 1 1 1 0 HCO3- transporter family CDC45 PF02724.14 EKX31248.1 - 0.83 7.9 22.5 1.2 7.3 22.5 1.3 1 0 0 1 1 1 0 CDC45-like protein GET2 PF08690.10 EKX31248.1 - 0.93 9.1 33.9 1.5 8.4 33.9 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 LAP1C PF05609.12 EKX31248.1 - 1 8.4 29.3 1.5 7.8 29.3 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Ureide_permease PF07168.11 EKX31248.1 - 1.1 8.0 9.0 1.7 7.3 9.0 1.2 1 0 0 1 1 1 0 Ureide permease Trypan_PARP PF05887.11 EKX31248.1 - 1.3 9.0 11.0 2.6 8.0 11.0 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ASC PF00858.24 EKX31248.1 - 1.4 7.8 16.5 2.1 7.2 16.5 1.2 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel DUF2207 PF09972.9 EKX31248.1 - 1.6 7.4 3.4 4.1 6.1 3.4 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) SLC12 PF03522.15 EKX31248.1 - 1.7 7.6 29.5 2.6 7.0 29.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 PAT1 PF09770.9 EKX31248.1 - 2 6.6 50.0 2.7 6.2 50.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Exonuc_VII_L PF02601.15 EKX31248.1 - 2.3 7.7 21.6 3.4 7.1 21.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit CSG2 PF16965.5 EKX31248.1 - 2.9 6.7 11.1 4.4 6.2 11.1 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator Membralin PF09746.9 EKX31248.1 - 3.6 6.5 14.0 5.3 6.0 14.0 1.3 1 0 0 1 1 1 0 Tumour-associated protein Cellulose_synt PF03552.14 EKX31248.1 - 4 5.8 8.0 5.2 5.4 8.0 1.1 1 0 0 1 1 1 0 Cellulose synthase Neur_chan_memb PF02932.16 EKX31248.1 - 4.2 7.4 24.6 8.4 6.4 24.6 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2347 PF09804.9 EKX31248.1 - 4.3 6.8 11.3 7 6.1 11.3 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) LMBR1 PF04791.16 EKX31248.1 - 4.3 6.1 13.0 6.4 5.6 13.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Nucleo_P87 PF07267.11 EKX31248.1 - 5.6 5.7 25.7 7.8 5.2 25.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SRP-alpha_N PF04086.13 EKX31248.1 - 8.2 6.3 31.9 13 5.7 31.9 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal BPL_N PF09825.9 EKX31248.1 - 9.8 5.1 14.4 15 4.5 14.4 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal RNase_P_Rpp14 PF01900.19 EKX31249.1 - 5.4e-10 39.4 0.0 7.3e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family Myb_DNA-binding PF00249.31 EKX31251.1 - 1.4e-09 38.0 0.0 7.7e-09 35.6 0.0 1.9 1 1 0 1 1 1 1 Myb-like DNA-binding domain TEA PF01285.18 EKX31251.1 - 0.0055 16.8 0.1 0.011 15.8 0.1 1.5 1 1 0 1 1 1 1 TEA/ATTS domain Pam17 PF08566.10 EKX31251.1 - 0.078 12.8 0.0 0.089 12.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Flg_hook PF02120.16 EKX31252.1 - 0.057 13.3 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK Myb_DNA-binding PF00249.31 EKX31253.1 - 9.1e-09 35.4 0.1 4.6e-08 33.1 0.1 1.9 1 1 0 1 1 1 1 Myb-like DNA-binding domain TEA PF01285.18 EKX31253.1 - 0.026 14.6 0.0 0.062 13.4 0.0 1.6 1 1 0 1 1 1 0 TEA/ATTS domain EGF_2 PF07974.13 EKX31255.1 - 7.4e-07 29.4 44.2 9.1e-05 22.7 15.9 5.4 3 2 2 5 5 5 2 EGF-like domain EGF PF00008.27 EKX31255.1 - 0.0003 21.0 27.3 0.007 16.6 10.8 5.3 5 0 0 5 5 5 3 EGF-like domain Laminin_EGF PF00053.24 EKX31255.1 - 0.018 15.1 10.1 0.018 15.1 10.1 4.3 3 2 1 4 4 4 0 Laminin EGF domain DSL PF01414.19 EKX31255.1 - 0.3 11.4 48.8 0.1 12.9 18.7 3.1 3 0 0 3 3 3 0 Delta serrate ligand 2OG-FeII_Oxy_3 PF13640.6 EKX31257.1 - 5.5e-09 36.8 0.0 3.4e-08 34.3 0.0 2.1 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily CRAL_TRIO PF00650.20 EKX31258.1 - 3.4e-21 75.6 0.0 4.4e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EKX31258.1 - 6.2e-08 32.9 0.0 9.3e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain tRNA-synt_1 PF00133.22 EKX31259.1 - 2.5e-109 366.2 0.0 6.9e-108 361.5 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 EKX31259.1 - 3e-11 43.2 0.0 6.9e-09 35.5 0.0 2.2 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 EKX31259.1 - 8.1e-08 31.4 0.0 2.9e-06 26.3 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) Ras PF00071.22 EKX31260.1 - 1.1e-42 145.4 0.1 1.3e-42 145.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EKX31260.1 - 9.2e-28 96.9 0.0 1.4e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EKX31260.1 - 2.5e-11 43.3 0.0 3e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EKX31260.1 - 1.5e-05 24.9 0.3 0.16 11.9 0.1 2.3 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EKX31260.1 - 5.3e-05 23.3 0.0 7.9e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DLIC PF05783.11 EKX31260.1 - 0.00012 21.1 0.0 0.22 10.3 0.0 2.1 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) SRPRB PF09439.10 EKX31260.1 - 0.00017 21.1 0.0 0.00044 19.7 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EKX31260.1 - 0.00037 20.9 0.1 0.0013 19.1 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EKX31260.1 - 0.0054 16.7 0.1 0.0098 15.8 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EKX31260.1 - 0.0095 16.2 0.2 0.04 14.2 0.1 2.1 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 EKX31260.1 - 0.013 15.2 0.2 0.22 11.3 0.2 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 EKX31260.1 - 0.014 15.4 0.0 0.026 14.4 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 EKX31260.1 - 0.018 14.6 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EKX31260.1 - 0.029 14.1 0.1 0.074 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EKX31260.1 - 0.041 14.4 0.0 0.064 13.8 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 EKX31260.1 - 0.068 12.7 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Gtr1_RagA PF04670.12 EKX31260.1 - 0.079 12.3 0.1 0.18 11.1 0.0 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region YwhD PF08741.10 EKX31260.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 YwhD family TniB PF05621.11 EKX31260.1 - 0.16 11.3 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Na_Ca_ex PF01699.24 EKX31261.1 - 4.5e-29 101.4 49.6 3.3e-20 72.6 19.3 3.5 2 1 1 3 3 3 2 Sodium/calcium exchanger protein AdoHcyase PF05221.17 EKX31261.1 - 0.021 14.0 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase Zn_clus PF00172.18 EKX31262.1 - 1.3e-10 41.2 35.6 4.4e-05 23.5 12.7 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 EKX31263.1 - 4.6e-11 42.6 35.2 1.4e-05 25.1 12.3 2.2 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain HalX PF08663.10 EKX31264.1 - 0.055 13.8 6.0 0.086 13.2 4.9 1.9 1 1 0 1 1 1 0 HalX domain IZUMO PF15005.6 EKX31264.1 - 0.39 11.2 7.4 9.9 6.7 3.9 2.3 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Syntaxin-6_N PF09177.11 EKX31264.1 - 0.71 10.5 6.1 0.89 10.2 4.1 2.3 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Spc7 PF08317.11 EKX31264.1 - 1.2 7.9 17.8 0.31 9.9 11.7 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein YscO PF07321.12 EKX31264.1 - 1.3 9.0 11.8 0.7 9.8 8.1 2.1 2 0 0 2 2 2 0 Type III secretion protein YscO APG6_N PF17675.1 EKX31264.1 - 1.6 9.2 13.8 7.5 7.1 10.4 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region MitMem_reg PF13012.6 EKX31264.1 - 1.9 8.9 6.9 0.3 11.5 0.8 2.4 2 2 0 2 2 2 0 Maintenance of mitochondrial structure and function Fib_alpha PF08702.10 EKX31264.1 - 2.7 8.2 12.2 2.3 8.4 0.2 2.9 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family RWP-RK PF02042.15 EKX31266.1 - 3.6e-12 46.1 0.0 6.5e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain 2-Hacid_dh_C PF02826.19 EKX31267.1 - 7.1e-50 168.8 0.0 9.6e-50 168.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EKX31267.1 - 1.2e-24 86.5 0.0 1.4e-24 86.3 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_7 PF13241.6 EKX31267.1 - 0.0079 16.6 0.1 0.057 13.9 0.1 2.2 2 0 0 2 2 2 1 Putative NAD(P)-binding TrkA_N PF02254.18 EKX31267.1 - 0.056 13.7 0.2 0.19 12.0 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain F420_oxidored PF03807.17 EKX31267.1 - 0.069 13.7 0.0 0.48 11.0 0.0 2.4 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Pkinase PF00069.25 EKX31268.1 - 9.1e-50 169.5 0.0 1.1e-49 169.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX31268.1 - 1.3e-23 83.6 0.0 1.7e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX31268.1 - 0.0018 17.7 0.1 0.0028 17.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EKX31268.1 - 0.02 14.2 0.0 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 EKX31268.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pepdidase_M14_N PF18027.1 EKX31269.1 - 8.3e-14 51.9 0.7 1.3e-13 51.3 0.7 1.3 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 EKX31269.1 - 4.9e-12 46.2 0.0 6e-11 42.7 0.0 2.1 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 EKX31269.1 - 0.18 10.8 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family FAM47 PF14642.6 EKX31270.1 - 0.00033 20.3 5.7 0.00039 20.1 5.7 1.2 1 0 0 1 1 1 1 FAM47 family ASH PF15780.5 EKX31271.1 - 4.8e-05 23.5 0.5 1.7 8.9 0.0 4.6 5 0 0 5 5 5 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 EKX31271.1 - 0.0002 21.5 0.4 0.03 14.5 0.0 3.9 5 0 0 5 5 5 1 Flagellar-associated PapD-like EF-hand_7 PF13499.6 EKX31271.1 - 0.004 17.6 0.3 0.022 15.2 0.3 2.4 1 0 0 1 1 1 1 EF-hand domain pair Trs65 PF12735.7 EKX31271.1 - 0.009 15.5 0.1 0.029 13.8 0.1 1.8 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 DUF1573 PF07610.11 EKX31271.1 - 0.013 15.6 0.6 44 4.2 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF1573) EF-hand_6 PF13405.6 EKX31271.1 - 0.013 15.4 0.0 0.43 10.6 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 EKX31271.1 - 0.018 14.5 0.0 0.13 11.9 0.0 2.5 2 0 0 2 2 2 0 EF hand Transglut_C PF00927.22 EKX31271.1 - 0.051 13.7 0.0 0.69 10.1 0.0 3.0 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain EF-hand_5 PF13202.6 EKX31271.1 - 0.077 12.5 0.1 0.19 11.3 0.1 1.7 1 0 0 1 1 1 0 EF hand YfhE PF14152.6 EKX31272.1 - 0.14 12.2 0.0 0.76 9.9 0.0 2.0 2 0 0 2 2 2 0 YfhE-like protein Ion_trans PF00520.31 EKX31273.1 - 6.9e-23 81.1 6.5 1.1e-22 80.5 6.5 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX31273.1 - 1.5e-12 47.3 2.2 1.5e-12 47.3 2.2 2.3 2 0 0 2 2 2 1 Ion channel DUF2207 PF09972.9 EKX31273.1 - 0.22 10.3 0.1 0.26 10.0 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Seryl_tRNA_N PF02403.22 EKX31274.1 - 0.016 15.4 9.6 0.13 12.5 0.7 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Gtr1_RagA PF04670.12 EKX31274.1 - 0.072 12.4 0.7 0.13 11.6 0.7 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF4391 PF14335.6 EKX31274.1 - 0.48 10.1 9.0 0.18 11.5 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) Snf7 PF03357.21 EKX31274.1 - 0.78 9.3 9.6 0.68 9.5 2.9 2.6 2 0 0 2 2 2 0 Snf7 ABC_tran_CTD PF16326.5 EKX31274.1 - 2.8 8.3 10.4 0.13 12.6 0.6 2.9 2 0 0 2 2 2 0 ABC transporter C-terminal domain APG6_N PF17675.1 EKX31274.1 - 3.3 8.2 17.5 0.61 10.6 0.8 2.9 3 0 0 3 3 3 0 Apg6 coiled-coil region CCDC-167 PF15188.6 EKX31274.1 - 4.4 7.7 8.9 2.1 8.7 0.7 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Prefoldin_2 PF01920.20 EKX31274.1 - 8.5 6.4 11.3 13 5.8 1.4 2.8 2 0 0 2 2 2 0 Prefoldin subunit IRF-2BP1_2 PF11261.8 EKX31275.1 - 0.46 10.1 2.5 72 3.0 0.0 3.1 3 0 0 3 3 3 0 Interferon regulatory factor 2-binding protein zinc finger Connexin PF00029.19 EKX31276.1 - 0.044 13.6 1.7 0.51 10.1 0.1 2.5 2 0 0 2 2 2 0 Connexin DUF913 PF06025.12 EKX31276.1 - 0.13 11.2 0.9 13 4.6 0.1 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) GRP PF07172.11 EKX31276.1 - 0.49 11.1 0.0 0.49 11.1 0.0 4.3 5 0 0 5 5 5 0 Glycine rich protein family INTS5_N PF14837.6 EKX31276.1 - 0.58 9.7 3.0 1 8.9 0.1 2.7 3 0 0 3 3 3 0 Integrator complex subunit 5 N-terminus SET PF00856.28 EKX31276.1 - 0.61 10.5 5.2 11 6.4 0.6 2.7 2 1 0 2 2 2 0 SET domain GOLD_2 PF13897.6 EKX31276.1 - 1.2 9.6 6.0 17 5.9 0.8 3.1 3 0 0 3 3 3 0 Golgi-dynamics membrane-trafficking CPSF100_C PF13299.6 EKX31276.1 - 1.9 8.7 8.9 0.25 11.5 0.1 3.0 4 0 0 4 4 4 0 Cleavage and polyadenylation factor 2 C-terminal Ank_4 PF13637.6 EKX31277.1 - 1.5e-17 63.7 0.2 2.4e-08 34.3 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX31277.1 - 3.6e-12 46.7 0.1 1e-11 45.3 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX31277.1 - 1.1e-08 35.1 0.5 0.013 15.8 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX31277.1 - 1.3e-07 31.4 0.0 0.2 12.3 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 EKX31277.1 - 4.6e-05 23.7 0.2 1.4 9.5 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat WD40 PF00400.32 EKX31278.1 - 1.5e-13 50.9 2.2 3.1e-08 34.1 0.0 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.8 EKX31278.1 - 0.0013 17.5 1.1 0.11 11.1 0.1 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EKX31278.1 - 0.061 11.8 0.1 0.071 11.6 0.1 1.0 1 0 0 1 1 1 0 Cytochrome D1 heme domain Tho2 PF11262.8 EKX31279.1 - 0.14 11.4 2.9 0.14 11.3 2.9 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 TRAP_alpha PF03896.16 EKX31279.1 - 1.3 8.2 5.7 1.5 8.0 5.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF1682 PF07946.14 EKX31279.1 - 1.5 7.9 9.5 1.8 7.7 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Ank_2 PF12796.7 EKX31280.1 - 2.7e-39 133.6 0.4 2.1e-08 34.7 0.0 5.1 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX31280.1 - 1e-22 80.1 0.0 0.0016 18.9 0.0 6.3 3 1 5 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX31280.1 - 7.6e-22 77.1 2.9 0.088 13.2 0.0 8.5 3 3 6 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX31280.1 - 8e-18 62.7 0.0 2.4 9.0 0.0 9.5 9 0 0 9 9 9 3 Ankyrin repeat Ank PF00023.30 EKX31280.1 - 1.4e-08 34.8 0.6 29 5.3 0.0 7.5 8 0 0 8 8 8 0 Ankyrin repeat Ins_beta PF03488.14 EKX31280.1 - 8.8e-06 25.6 21.8 16 5.6 0.7 8.1 7 1 1 8 8 8 1 Nematode insulin-related peptide beta type Baculo_PEP_N PF04512.12 EKX31280.1 - 0.0015 18.8 0.2 18 5.7 0.0 4.5 1 1 3 5 5 5 1 Baculovirus polyhedron envelope protein, PEP, N terminus VHS PF00790.19 EKX31280.1 - 0.0016 18.3 6.5 48 3.8 0.0 6.0 6 2 1 7 7 7 0 VHS domain FANCI_S3 PF14677.6 EKX31280.1 - 0.0037 17.0 0.0 0.99 9.1 0.0 2.9 1 1 1 3 3 3 1 FANCI solenoid 3 SPATA24 PF15175.6 EKX31280.1 - 0.0061 16.5 2.1 15 5.5 0.0 3.2 2 1 0 3 3 3 2 Spermatogenesis-associated protein 24 Guanylate_cyc PF00211.20 EKX31281.1 - 1.4e-08 34.6 0.0 2.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain WD40 PF00400.32 EKX31283.1 - 2.2e-60 199.2 20.0 9.7e-10 38.9 0.2 10.1 10 0 0 10 10 10 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX31283.1 - 4.6e-17 62.1 0.9 0.0056 17.0 0.0 6.0 2 1 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX31283.1 - 4.9e-05 22.4 2.3 0.38 9.7 1.4 5.0 3 2 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EKX31283.1 - 0.00092 18.0 6.3 1.1 7.8 0.0 4.9 2 1 4 6 6 6 2 Nucleoporin Nup120/160 WD40_like PF17005.5 EKX31283.1 - 0.0028 17.1 0.0 2.6 7.3 0.0 3.4 2 1 0 3 3 3 2 WD40-like domain Frtz PF11768.8 EKX31283.1 - 0.0079 14.6 0.1 3.7 5.8 0.0 3.2 3 1 1 4 4 4 2 WD repeat-containing and planar cell polarity effector protein Fritz Inhibitor_I66 PF16850.5 EKX31283.1 - 0.12 12.3 0.1 4.1 7.3 0.1 2.4 2 0 0 2 2 2 0 Peptidase inhibitor I66 ENOD93 PF03386.14 EKX31284.1 - 7.4e-07 29.0 4.7 28 4.7 0.0 7.5 1 1 6 7 7 7 3 Early nodulin 93 ENOD93 protein YjcZ PF13990.6 EKX31284.1 - 0.013 14.9 0.6 6.5 6.0 0.3 3.0 1 1 1 2 2 2 0 YjcZ-like protein TNT PF14021.6 EKX31284.1 - 1.6 9.4 23.7 3.6e+03 -1.4 7.2 7.4 1 1 1 2 2 2 0 Tuberculosis necrotizing toxin AAA_6 PF12774.7 EKX31285.1 - 3.6e-145 483.0 0.0 1.8e-142 474.1 0.0 2.5 2 0 0 2 2 2 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EKX31285.1 - 3.2e-139 464.4 0.8 3.2e-139 464.4 0.8 2.2 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.7 EKX31285.1 - 3.9e-79 264.4 0.3 2.7e-76 255.1 0.0 3.1 3 0 0 3 3 3 2 P-loop containing dynein motor region Dynein_AAA_lid PF17852.1 EKX31285.1 - 2.5e-29 102.0 0.0 9.2e-29 100.1 0.0 2.1 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EKX31285.1 - 4e-10 39.8 0.1 0.018 15.1 0.0 5.1 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 EKX31285.1 - 3.2e-05 24.1 0.1 0.00014 22.0 0.1 2.3 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 EKX31285.1 - 7.3e-05 23.2 0.1 0.26 11.7 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX31285.1 - 0.00014 22.3 0.0 0.38 11.1 0.0 3.7 4 0 0 4 4 3 2 AAA ATPase domain AAA_22 PF13401.6 EKX31285.1 - 0.00043 20.6 0.0 8.3 6.7 0.0 3.8 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EKX31285.1 - 0.0014 19.0 0.0 2.4 8.6 0.0 2.9 2 0 0 2 2 2 2 RNA helicase DUF2730 PF10805.8 EKX31285.1 - 0.0062 16.6 0.7 0.53 10.4 0.1 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2730) AAA_30 PF13604.6 EKX31285.1 - 0.0063 16.3 0.8 0.38 10.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.7 EKX31285.1 - 0.033 13.1 0.1 0.2 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain Sigma54_activat PF00158.26 EKX31285.1 - 0.05 13.3 0.1 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF1664 PF07889.12 EKX31285.1 - 3.2 7.8 5.6 1.1 9.3 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Pkinase_Tyr PF07714.17 EKX31286.1 - 1.3e-48 165.6 0.0 1.5e-48 165.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX31286.1 - 1.5e-44 152.3 0.0 2e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EKX31286.1 - 8.3e-05 22.0 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family NHL PF01436.21 EKX31287.1 - 9.3e-11 41.2 3.1 0.00028 20.8 0.0 4.9 5 1 0 5 5 5 3 NHL repeat Lactonase PF10282.9 EKX31287.1 - 0.0097 15.2 0.1 2.4 7.3 0.0 2.2 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller SGL PF08450.12 EKX31287.1 - 0.037 13.6 0.1 5 6.6 0.0 2.3 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 EKX31287.1 - 0.044 13.9 0.0 0.5 10.5 0.0 2.2 2 0 0 2 2 2 0 Strictosidine synthase SBP56 PF05694.11 EKX31287.1 - 0.09 11.6 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 56kDa selenium binding protein (SBP56) DUF836 PF05768.14 EKX31288.1 - 9.6e-16 58.0 0.0 1.2e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 EKX31288.1 - 0.0052 17.0 0.0 0.0072 16.5 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Methyltransf_24 PF13578.6 EKX31290.1 - 5.5e-10 40.2 0.1 1.2e-09 39.1 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EKX31290.1 - 0.0015 17.7 0.0 0.0027 16.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Ank_2 PF12796.7 EKX31291.1 - 7.9e-14 52.0 0.1 2.6e-13 50.4 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX31291.1 - 1.9e-11 44.0 0.1 2.7e-08 33.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX31291.1 - 3.7e-11 43.3 0.0 6.3e-10 39.4 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX31291.1 - 1.6e-10 40.3 0.0 0.00015 21.9 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EKX31291.1 - 1.5e-08 34.7 0.0 0.0086 16.5 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Acetyltransf_10 PF13673.7 EKX31291.1 - 0.0043 17.0 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EKX31291.1 - 0.044 14.0 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Pes-10 PF07149.11 EKX31292.1 - 0.035 13.2 1.3 0.044 12.8 1.3 1.2 1 0 0 1 1 1 0 Pes-10 Radial_spoke PF04712.12 EKX31292.1 - 0.071 12.0 3.1 0.09 11.7 3.1 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Pox_Ag35 PF03286.14 EKX31292.1 - 0.37 10.6 5.6 0.58 9.9 5.6 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM176 PF14851.6 EKX31292.1 - 0.47 10.1 4.8 0.8 9.4 4.8 1.4 1 0 0 1 1 1 0 FAM176 family Astro_capsid_p PF12226.8 EKX31292.1 - 1.5 7.9 5.4 1.8 7.6 5.4 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RRN3 PF05327.11 EKX31292.1 - 2.2 6.7 4.5 2.9 6.3 4.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.12 EKX31292.1 - 4.3 6.6 11.5 6.3 6.0 11.5 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 EKX31292.1 - 4.6 7.7 16.1 7.7 7.0 16.1 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.12 EKX31292.1 - 7.9 4.5 10.5 9.9 4.2 10.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF3298 PF11738.8 EKX31293.1 - 0.061 14.4 0.1 0.45 11.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3298) Tcp11 PF05794.13 EKX31294.1 - 4e-35 121.8 3.3 7.7e-35 120.8 3.3 1.4 1 0 0 1 1 1 1 T-complex protein 11 YL1 PF05764.13 EKX31296.1 - 6 6.9 33.8 10 6.2 33.8 1.6 1 1 0 1 1 1 0 YL1 nuclear protein Peptidase_C14 PF00656.22 EKX31299.1 - 7.8e-49 166.9 1.6 4.2e-37 128.4 0.1 2.1 2 0 0 2 2 2 2 Caspase domain Raptor_N PF14538.6 EKX31299.1 - 0.023 14.6 0.0 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain Beta_helix PF13229.6 EKX31300.1 - 0.00095 19.0 9.0 0.0019 18.1 8.9 1.6 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 EKX31300.1 - 0.37 10.0 5.8 1 8.6 5.6 1.7 1 1 1 2 2 2 0 Periplasmic copper-binding protein (NosD) Pex14_N PF04695.13 EKX31301.1 - 0.36 11.5 42.0 0.44 11.2 42.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CobT PF06213.12 EKX31301.1 - 0.66 9.3 41.5 0.77 9.1 41.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CCDC53 PF10152.9 EKX31301.1 - 0.92 9.9 30.9 0.99 9.8 30.9 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DDHD PF02862.17 EKX31301.1 - 2.3 8.3 27.2 2.9 8.0 27.2 1.2 1 0 0 1 1 1 0 DDHD domain Rtf2 PF04641.12 EKX31301.1 - 2.9 7.2 26.8 3.3 7.0 26.8 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger SpoIIP PF07454.11 EKX31301.1 - 2.9 7.3 32.1 4.1 6.8 32.1 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 EKX31301.1 - 3.7 6.2 38.0 3.7 6.2 38.0 1.0 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.8 EKX31301.1 - 3.7 6.2 26.0 4.4 6.0 26.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF1387 PF07139.11 EKX31301.1 - 4.5 6.9 29.0 5.3 6.7 29.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) RR_TM4-6 PF06459.12 EKX31301.1 - 5.1 6.8 33.0 5.9 6.6 33.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.8 EKX31301.1 - 5.1 5.9 28.4 6.1 5.6 28.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF913 PF06025.12 EKX31301.1 - 5.2 5.9 23.3 6.2 5.7 23.3 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2828 PF11443.8 EKX31301.1 - 5.6 4.9 29.6 6 4.8 29.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) FAM60A PF15396.6 EKX31301.1 - 5.8 6.9 25.6 6.6 6.7 25.6 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Velvet PF11754.8 EKX31301.1 - 6 6.7 29.0 7 6.5 29.0 1.0 1 0 0 1 1 1 0 Velvet factor Gti1_Pac2 PF09729.9 EKX31301.1 - 6.4 6.8 27.0 7.5 6.6 27.0 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family SLC12 PF03522.15 EKX31301.1 - 6.6 5.6 32.8 7.2 5.5 32.8 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Band_3_cyto PF07565.13 EKX31301.1 - 6.8 6.4 27.1 8.5 6.1 27.1 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Endostatin PF06482.11 EKX31301.1 - 7.3 6.0 27.7 7.8 5.9 27.7 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin PIP5K PF01504.18 EKX31301.1 - 7.4 5.7 24.4 9.1 5.4 24.4 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase eIF-3_zeta PF05091.12 EKX31301.1 - 7.6 5.4 41.8 8.9 5.2 41.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.9 EKX31301.1 - 8.3 4.5 46.0 8.8 4.5 46.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SelP_N PF04592.14 EKX31301.1 - 8.5 5.7 25.3 9.7 5.5 25.3 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region YABBY PF04690.13 EKX31301.1 - 9 6.8 23.2 10 6.7 23.2 1.1 1 0 0 1 1 1 0 YABBY protein XRN_M PF17846.1 EKX31301.1 - 9.3 5.1 24.9 11 4.9 24.9 1.0 1 0 0 1 1 1 0 Xrn1 helical domain DUF3295 PF11702.8 EKX31301.1 - 9.4 5.5 30.0 11 5.3 30.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) TFIIA PF03153.13 EKX31301.1 - 9.5 6.1 63.8 13 5.6 63.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 EKX31301.1 - 9.9 4.3 30.4 11 4.1 30.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Glyco_transf_41 PF13844.6 EKX31302.1 - 6.9e-08 31.4 0.1 8.4e-08 31.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 41 DUF4131 PF13567.6 EKX31302.1 - 6 6.5 8.7 7.4 6.2 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Mon1 PF03164.14 EKX31305.1 - 0.045 12.8 1.4 0.074 12.1 1.4 1.2 1 0 0 1 1 1 0 Trafficking protein Mon1 L27_1 PF09058.10 EKX31305.1 - 0.28 11.2 2.2 1.8 8.6 0.1 2.7 3 0 0 3 3 3 0 L27_1 Peptidase_M24 PF00557.24 EKX31306.1 - 2.3e-55 187.5 0.1 2.8e-55 187.3 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Mpv17_PMP22 PF04117.12 EKX31307.1 - 2.7e-09 37.1 1.4 3.2e-09 36.9 0.3 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family DUF1952 PF09189.10 EKX31307.1 - 0.16 11.8 0.1 0.39 10.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1952) TPR_2 PF07719.17 EKX31308.1 - 0.00052 19.9 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX31308.1 - 0.0017 18.1 0.5 0.0072 16.1 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat SPRY PF00622.28 EKX31308.1 - 0.019 15.1 0.1 0.044 13.9 0.1 1.6 2 0 0 2 2 2 0 SPRY domain TPR_12 PF13424.6 EKX31308.1 - 0.12 12.7 0.0 0.73 10.2 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat ABC_tran PF00005.27 EKX31309.1 - 0.0033 17.9 0.1 0.026 15.1 0.0 2.6 2 0 0 2 2 2 1 ABC transporter MetRS-N PF09635.10 EKX31309.1 - 0.0039 17.7 0.3 0.0099 16.4 0.3 1.6 1 0 0 1 1 1 1 MetRS-N binding domain RsgA_GTPase PF03193.16 EKX31309.1 - 0.0096 15.8 0.2 0.042 13.8 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EKX31309.1 - 0.018 15.1 0.0 7.9 6.6 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 EKX31309.1 - 0.073 13.1 0.9 0.25 11.4 0.0 2.4 2 0 0 2 2 2 0 Dynamin family DUF87 PF01935.17 EKX31309.1 - 0.086 12.9 2.6 13 5.8 0.0 3.6 3 0 0 3 3 3 0 Helicase HerA, central domain YpjP PF14005.6 EKX31309.1 - 0.087 12.9 0.7 1.9 8.5 0.7 2.9 2 0 0 2 2 2 0 YpjP-like protein AAA_7 PF12775.7 EKX31309.1 - 0.15 11.6 1.3 0.4 10.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF1524 PF07510.11 EKX31309.1 - 0.27 11.1 2.4 0.32 10.9 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1524) OTU PF02338.19 EKX31309.1 - 0.65 10.5 2.2 1.2 9.6 0.6 2.3 2 0 0 2 2 2 0 OTU-like cysteine protease DUF563 PF04577.14 EKX31312.1 - 2.3e-08 34.4 0.0 4e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Tantalus PF15386.6 EKX31312.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Drosophila Tantalus-like Glyco_tranf_2_3 PF13641.6 EKX31312.1 - 0.16 11.8 0.3 2.3 8.1 0.0 2.1 1 1 1 2 2 2 0 Glycosyltransferase like family 2 EF-hand_6 PF13405.6 EKX31313.1 - 2e-09 36.6 0.3 0.00059 19.6 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EKX31313.1 - 2.6e-09 37.4 0.3 8.3e-09 35.8 0.3 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX31313.1 - 5.4e-09 35.0 0.1 0.0051 16.3 0.2 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX31313.1 - 2.1e-08 33.9 0.9 0.0024 17.7 0.1 3.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX31313.1 - 3.5e-08 32.6 0.4 0.011 15.2 0.2 2.8 2 0 0 2 2 2 2 EF hand DUF1163 PF06651.11 EKX31313.1 - 6.7e-05 22.9 11.3 64 3.7 0.0 8.1 8 0 0 8 8 8 0 Protein of unknown function (DUF1163) MurB_C PF02873.16 EKX31313.1 - 0.00066 19.7 4.9 5.8 7.0 0.1 7.1 8 0 0 8 8 8 1 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain Collagen PF01391.18 EKX31313.1 - 0.00096 18.9 14.8 0.00096 18.9 14.8 4.4 3 1 0 3 3 1 1 Collagen triple helix repeat (20 copies) SPARC_Ca_bdg PF10591.9 EKX31313.1 - 0.052 13.9 2.6 0.06 13.7 0.1 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region UvrD_C PF13361.6 EKX31313.1 - 1.2 8.4 8.4 0.23 10.8 2.2 2.3 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain DUF948 PF06103.11 EKX31313.1 - 2 8.7 6.5 38 4.6 0.3 4.3 4 0 0 4 4 3 0 Bacterial protein of unknown function (DUF948) Kelch_1 PF01344.25 EKX31314.1 - 6.1e-08 32.1 1.5 0.0063 16.1 0.0 4.5 3 1 0 3 3 3 2 Kelch motif TRP PF06011.12 EKX31314.1 - 4.7e-06 25.6 2.4 4.7e-06 25.6 2.4 1.9 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel Kelch_2 PF07646.15 EKX31314.1 - 2.2e-05 24.2 1.4 0.0014 18.5 0.0 4.2 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.6 EKX31314.1 - 2.5e-05 24.5 7.8 0.54 10.6 0.3 5.0 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_4 PF13418.6 EKX31314.1 - 8e-05 22.6 10.1 0.19 11.8 0.2 5.2 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.6 EKX31314.1 - 0.00024 21.2 8.7 0.37 11.2 0.1 5.9 4 1 1 5 5 5 2 Kelch motif Chlam_PMP PF02415.17 EKX31314.1 - 0.0074 16.7 9.9 4.4 8.0 0.1 5.2 5 0 0 5 5 5 2 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Kelch_5 PF13854.6 EKX31314.1 - 0.39 10.8 0.0 0.39 10.8 0.0 4.4 5 0 0 5 5 5 0 Kelch motif DUF1700 PF08006.11 EKX31320.1 - 1.1 8.7 5.3 3.1 7.3 5.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) SDA1 PF05285.12 EKX31321.1 - 0.38 10.1 27.2 0.43 9.9 27.2 1.2 1 0 0 1 1 1 0 SDA1 ALMT PF11744.8 EKX31321.1 - 0.86 8.4 7.7 1.1 8.0 7.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PPP4R2 PF09184.11 EKX31321.1 - 2.7 7.5 22.4 3.4 7.2 22.4 1.1 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 EKX31321.1 - 2.8 6.0 26.8 3.4 5.8 26.8 1.3 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 EKX31321.1 - 9.2 4.9 16.3 12 4.5 16.3 1.2 1 0 0 1 1 1 0 Presenilin MMR_HSR1 PF01926.23 EKX31322.1 - 7.4e-22 77.6 0.0 2.2e-21 76.1 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EKX31322.1 - 2.2e-06 27.3 0.0 3.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B cNMP_binding PF00027.29 EKX31322.1 - 0.0044 17.1 0.0 0.0074 16.3 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain MeaB PF03308.16 EKX31322.1 - 0.017 14.1 0.3 0.11 11.5 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB HAUS-augmin3 PF14932.6 EKX31322.1 - 0.04 13.5 0.0 0.057 13.0 0.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Dynamin_N PF00350.23 EKX31322.1 - 0.14 12.2 0.0 0.64 10.1 0.0 2.2 1 1 0 1 1 1 0 Dynamin family ABC_tran PF00005.27 EKX31322.1 - 0.19 12.3 0.0 0.5 10.9 0.0 1.7 2 0 0 2 2 2 0 ABC transporter Pkinase PF00069.25 EKX31324.1 - 1.5e-11 44.2 0.0 4.5e-11 42.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX31324.1 - 1.4e-06 27.8 0.0 2.8e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX31324.1 - 0.013 14.3 0.0 0.013 14.3 0.0 3.5 2 1 1 3 3 3 0 Fungal protein kinase DUF4558 PF15104.6 EKX31324.1 - 0.4 10.8 8.8 0.2 11.7 4.7 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4558) Pkinase PF00069.25 EKX31325.1 - 1.8e-18 66.9 0.0 2.3e-18 66.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX31325.1 - 4.7e-09 35.9 0.0 5.9e-09 35.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX31325.1 - 5.5e-08 32.0 0.0 7.1e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX31325.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family TPR_2 PF07719.17 EKX31326.1 - 9.8e-09 34.7 2.8 0.027 14.6 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX31326.1 - 3.5e-08 32.9 0.3 9.4e-05 22.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX31326.1 - 1.6e-06 28.7 1.3 0.00026 21.6 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX31326.1 - 1e-05 26.0 1.9 0.00024 21.5 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX31326.1 - 6.2e-05 23.2 4.9 0.099 12.9 1.0 3.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX31326.1 - 0.00041 20.8 2.6 0.76 10.5 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX31326.1 - 0.0036 17.4 0.2 0.049 13.7 0.0 2.5 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 EKX31326.1 - 0.0043 17.0 1.1 0.32 11.1 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX31326.1 - 0.0068 16.6 1.6 0.034 14.4 0.3 2.5 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EKX31326.1 - 0.018 14.3 1.2 0.059 12.6 0.3 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX31326.1 - 0.018 15.2 0.0 0.086 13.1 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX31326.1 - 0.086 13.7 10.3 3.1 8.9 0.0 4.4 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EKX31326.1 - 0.11 12.6 5.3 0.079 13.1 1.4 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 EKX31327.1 - 2.4e-38 131.9 0.0 2.6e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX31327.1 - 4.2e-15 55.8 0.0 4.7e-15 55.7 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain U-box PF04564.15 EKX31328.1 - 5.9e-19 68.0 0.0 6.9e-19 67.8 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX31328.1 - 0.00018 21.3 0.0 0.00025 20.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EKX31328.1 - 0.00028 20.9 0.1 0.00043 20.2 0.1 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-NOSIP PF15906.5 EKX31328.1 - 0.055 13.6 0.0 0.068 13.3 0.0 1.2 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein ACBP PF00887.19 EKX31329.1 - 3.2e-05 24.1 0.1 4.9e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein FAM176 PF14851.6 EKX31329.1 - 0.095 12.4 3.4 0.12 12.1 3.4 1.1 1 0 0 1 1 1 0 FAM176 family Tho2 PF11262.8 EKX31330.1 - 3.5e-75 253.0 6.9 8.4e-75 251.8 6.9 1.7 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 EKX31330.1 - 1.1e-74 252.2 1.3 1.5e-50 172.5 0.2 3.8 2 1 0 2 2 2 2 THO complex subunit 2 N-terminus Thoc2 PF11732.8 EKX31330.1 - 1.4e-19 69.9 0.1 7.8e-19 67.5 0.0 2.3 2 0 0 2 2 2 1 Transcription- and export-related complex subunit NAD_binding_8 PF13450.6 EKX31332.1 - 1.3e-08 34.9 0.1 2.2e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EKX31332.1 - 9.4e-07 28.7 0.4 1.4e-06 28.1 0.2 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EKX31332.1 - 9.5e-07 28.2 0.2 1.1e-06 28.0 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 EKX31332.1 - 2.6e-06 26.9 0.0 3.4e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EKX31332.1 - 4.9e-06 26.0 0.2 5.4e-06 25.9 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EKX31332.1 - 0.00025 20.3 0.4 0.00026 20.2 0.4 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EKX31332.1 - 0.00036 20.0 0.2 0.00046 19.7 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EKX31332.1 - 0.00053 20.5 0.8 0.00067 20.2 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EKX31332.1 - 0.00078 18.2 0.7 0.0015 17.3 0.3 1.6 1 1 1 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EKX31332.1 - 0.0015 17.8 0.0 0.0018 17.5 0.0 1.1 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 EKX31332.1 - 0.0066 15.8 0.0 0.0092 15.3 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 EKX31332.1 - 0.0084 15.4 0.1 0.0093 15.3 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 EKX31332.1 - 0.031 14.3 0.0 0.043 13.8 0.0 1.2 1 0 0 1 1 1 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 EKX31332.1 - 0.035 14.0 0.1 0.051 13.5 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 EKX31332.1 - 0.06 12.6 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EKX31332.1 - 0.077 11.8 0.1 0.087 11.6 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase S1 PF00575.23 EKX31333.1 - 2.4e-11 43.8 0.0 5.5e-09 36.2 0.0 2.1 2 0 0 2 2 2 2 S1 RNA binding domain S1_2 PF13509.6 EKX31333.1 - 9.3e-05 22.4 0.0 0.00018 21.5 0.0 1.6 1 0 0 1 1 1 1 S1 domain APOBEC1 PF18769.1 EKX31333.1 - 0.14 12.4 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 APOBEC1 TFIIA PF03153.13 EKX31335.1 - 0.015 15.4 14.2 0.021 14.9 14.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LacI PF00356.21 EKX31335.1 - 0.21 11.4 0.8 0.52 10.1 0.8 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family TPP_enzyme_N PF02776.18 EKX31335.1 - 0.68 9.5 0.0 0.68 9.5 0.0 2.1 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain SelP_N PF04592.14 EKX31335.1 - 2.6 7.4 8.8 5.1 6.4 8.8 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RWP-RK PF02042.15 EKX31336.1 - 9.4e-12 44.7 0.1 2.2e-11 43.6 0.1 1.6 1 0 0 1 1 1 1 RWP-RK domain HTH_28 PF13518.6 EKX31336.1 - 0.099 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HMMR_C PF15908.5 EKX31337.1 - 2.5e-08 34.4 7.9 2.5e-08 34.4 7.9 2.6 1 1 0 2 2 2 1 Hyaluronan mediated motility receptor C-terminal EutA PF06277.11 EKX31337.1 - 0.036 12.9 0.1 0.061 12.2 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutA NPV_P10 PF05531.12 EKX31337.1 - 0.41 11.1 6.5 0.2 12.2 0.8 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.6 EKX31337.1 - 0.64 8.6 21.5 1 7.9 21.5 1.3 1 0 0 1 1 1 0 AAA domain Leu_zip PF15294.6 EKX31337.1 - 3 7.3 29.0 2.8 7.4 15.0 2.5 1 1 1 2 2 2 0 Leucine zipper DUF4407 PF14362.6 EKX31337.1 - 5 6.4 21.6 60 2.8 21.6 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MbeD_MobD PF04899.12 EKX31337.1 - 5.9 7.1 12.4 0.062 13.4 1.9 2.9 2 1 0 2 2 2 0 MbeD/MobD like Endostatin PF06482.11 EKX31340.1 - 0.00021 20.9 13.0 0.00021 20.9 13.0 1.2 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin DDHD PF02862.17 EKX31340.1 - 0.017 15.3 16.0 0.021 15.0 16.0 1.3 1 0 0 1 1 1 0 DDHD domain Velvet PF11754.8 EKX31340.1 - 0.028 14.4 18.6 0.035 14.0 18.6 1.3 1 0 0 1 1 1 0 Velvet factor SID-1_RNA_chan PF13965.6 EKX31340.1 - 0.028 12.9 5.8 0.025 13.0 5.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Presenilin PF01080.17 EKX31340.1 - 0.041 12.7 25.9 0.042 12.6 25.9 1.2 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 EKX31340.1 - 0.047 12.7 28.0 0.053 12.5 28.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.12 EKX31340.1 - 0.099 12.4 22.3 0.11 12.3 22.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Paf1 PF03985.13 EKX31340.1 - 0.13 11.2 27.7 0.15 11.0 27.7 1.1 1 0 0 1 1 1 0 Paf1 Neur_chan_memb PF02932.16 EKX31340.1 - 0.16 12.0 15.4 0.18 11.8 15.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 EKX31340.1 - 0.22 9.8 18.6 0.22 9.8 18.6 1.2 1 0 0 1 1 1 0 CDC45-like protein UPF0560 PF10577.9 EKX31340.1 - 0.22 10.0 29.8 0.22 10.0 29.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4407 PF14362.6 EKX31340.1 - 0.25 10.7 21.8 0.27 10.6 21.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF913 PF06025.12 EKX31340.1 - 0.25 10.3 14.5 0.29 10.1 14.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PAT1 PF09770.9 EKX31340.1 - 0.26 9.5 39.4 0.27 9.5 39.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Band_3_cyto PF07565.13 EKX31340.1 - 0.29 10.9 18.8 0.39 10.5 18.8 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SLC12 PF03522.15 EKX31340.1 - 0.34 9.9 22.9 0.38 9.7 22.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Membralin PF09746.9 EKX31340.1 - 0.59 9.1 12.3 0.6 9.1 12.3 1.2 1 0 0 1 1 1 0 Tumour-associated protein Serinc PF03348.15 EKX31340.1 - 2.3 7.1 13.7 2.4 7.0 13.7 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Borrelia_P83 PF05262.11 EKX31340.1 - 2.8 6.3 24.1 2.7 6.4 24.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4746 PF15928.5 EKX31340.1 - 3.1 7.1 18.3 4.1 6.8 18.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Rrn6 PF10214.9 EKX31340.1 - 3.1 6.2 30.6 3.1 6.2 30.6 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Hid1 PF12722.7 EKX31340.1 - 3.5 5.6 22.5 3.5 5.6 22.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MMU163 PF17119.5 EKX31340.1 - 4 6.5 11.4 5.7 6.0 11.4 1.3 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis UPF0176_N PF17773.1 EKX31341.1 - 2.8e-23 82.1 0.0 7e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 EKX31341.1 - 3.7e-05 24.2 0.0 9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain TPR_12 PF13424.6 EKX31343.1 - 3.6e-23 81.6 7.7 1.1e-07 32.0 0.0 5.9 3 1 4 7 7 6 4 Tetratricopeptide repeat TPR_10 PF13374.6 EKX31343.1 - 2.9e-13 49.2 4.3 0.0036 17.1 0.0 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX31343.1 - 8.6e-09 34.9 7.7 0.034 14.2 0.9 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX31343.1 - 2.2e-07 30.4 10.9 0.00075 19.2 2.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX31343.1 - 5.4e-06 26.1 6.8 0.19 11.8 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX31343.1 - 1.1e-05 25.0 0.1 0.048 13.0 0.0 2.2 2 0 0 2 2 2 2 MalT-like TPR region SNAP PF14938.6 EKX31343.1 - 1.7e-05 24.4 0.9 5.3e-05 22.8 0.9 1.8 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_8 PF13181.6 EKX31343.1 - 0.00042 20.3 6.5 9.7 6.7 1.6 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX31343.1 - 0.0022 18.2 6.7 0.58 10.4 1.8 3.7 2 2 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EKX31343.1 - 0.012 16.0 0.3 0.7 10.4 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX31343.1 - 0.016 16.0 2.3 1.2 10.2 0.0 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat MIT PF04212.18 EKX31343.1 - 0.074 13.1 4.4 0.58 10.3 0.4 3.5 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 EKX31343.1 - 0.15 12.7 9.2 23 5.9 0.4 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat ABC_tran_Xtn PF12848.7 EKX31343.1 - 0.83 9.7 3.2 13 5.9 0.0 2.5 2 0 0 2 2 2 0 ABC transporter TPR_16 PF13432.6 EKX31343.1 - 2.3 8.9 6.4 1.1e+02 3.6 0.1 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat C2 PF00168.30 EKX31345.1 - 1e-07 32.2 0.0 0.00019 21.6 0.0 2.4 2 0 0 2 2 2 2 C2 domain NT-C2 PF10358.9 EKX31345.1 - 0.015 15.0 0.3 0.8 9.4 0.0 2.6 3 0 0 3 3 3 0 N-terminal C2 in EEIG1 and EHBP1 proteins Cupin_3 PF05899.12 EKX31345.1 - 0.024 14.3 0.0 0.065 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) PI3K_C2 PF00792.24 EKX31345.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 Cupin_2 PF07883.11 EKX31345.1 - 0.16 11.7 0.0 0.43 10.3 0.0 1.7 1 0 0 1 1 1 0 Cupin domain HSP70 PF00012.20 EKX31346.1 - 2.4e-158 528.1 4.2 2.6e-115 385.9 1.4 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EKX31346.1 - 3e-14 52.6 0.6 1.7e-10 40.2 0.2 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.18 EKX31346.1 - 0.00099 18.5 0.6 1.1 8.5 0.3 2.4 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase DDR PF08841.10 EKX31346.1 - 0.013 14.6 0.1 0.02 13.9 0.1 1.3 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.6 EKX31346.1 - 0.043 14.2 0.8 1.2 9.6 0.2 2.6 2 1 0 2 2 2 0 Cell division protein FtsA ADH_N PF08240.12 EKX31347.1 - 1.1e-07 31.6 6.2 3.6e-07 30.0 2.2 3.3 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TMPIT PF07851.13 EKX31348.1 - 0.3 10.3 1.4 0.44 9.7 1.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein DSPn PF14671.6 EKX31349.1 - 1.2e-29 103.6 0.0 2e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half AP2 PF00847.20 EKX31350.1 - 2.9e-14 53.0 7.1 1.4e-07 31.6 0.3 2.4 2 0 0 2 2 2 2 AP2 domain BSP_II PF05432.11 EKX31351.1 - 0.11 12.2 15.2 0.17 11.6 15.2 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Auts2 PF15336.6 EKX31351.1 - 0.32 11.1 4.1 0.5 10.5 4.1 1.2 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein GRP PF07172.11 EKX31351.1 - 0.81 10.4 32.7 1.5 9.6 32.7 1.3 1 0 0 1 1 1 0 Glycine rich protein family RR_TM4-6 PF06459.12 EKX31351.1 - 2.2 8.1 8.4 3.3 7.5 8.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Paf1 PF03985.13 EKX31351.1 - 3.3 6.6 11.9 4.6 6.1 11.9 1.1 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.14 EKX31351.1 - 6.4 4.9 6.8 8.5 4.5 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein XAP5 PF04921.14 EKX31351.1 - 7.3 6.3 11.6 11 5.7 11.6 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator MatE PF01554.18 EKX31353.1 - 4.2e-15 55.8 24.6 2.6e-13 50.0 15.3 2.7 2 1 1 3 3 3 2 MatE Polysacc_synt_C PF14667.6 EKX31353.1 - 0.0001 22.4 9.5 0.0001 22.4 9.5 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis C-terminal domain Lung_7-TM_R PF06814.13 EKX31353.1 - 0.005 16.1 0.4 0.013 14.7 0.4 1.6 1 0 0 1 1 1 1 Lung seven transmembrane receptor RRP7 PF12923.7 EKX31354.1 - 3.9e-08 33.5 11.1 1.3e-06 28.6 5.4 2.7 2 1 0 3 3 3 2 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_1 PF00076.22 EKX31354.1 - 0.0026 17.6 0.3 0.023 14.5 0.3 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EKX31354.1 - 0.016 15.3 0.0 0.041 14.0 0.0 1.7 1 1 1 2 2 2 0 RNA recognition motif cEGF PF12662.7 EKX31355.1 - 0.087 12.8 0.4 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 Complement Clr-like EGF-like MORN PF02493.20 EKX31356.1 - 1.7e-24 84.2 46.6 2.8e-07 30.0 1.0 6.3 6 0 0 6 6 6 6 MORN repeat zf-C3HC4_3 PF13920.6 EKX31359.1 - 3.8e-10 39.5 9.5 7.1e-10 38.6 9.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX31359.1 - 8e-06 26.1 11.7 1.5e-05 25.2 11.7 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EKX31359.1 - 0.00019 21.2 9.7 0.00039 20.2 9.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EKX31359.1 - 0.024 14.6 12.3 0.04 13.9 12.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Adeno_E3_15_3 PF03307.14 EKX31359.1 - 0.072 13.1 0.4 0.37 10.8 0.0 2.1 2 0 0 2 2 2 0 Adenovirus 15.3kD protein in E3 region zf-RING_4 PF14570.6 EKX31359.1 - 0.69 9.8 11.3 2 8.3 11.3 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 EKX31359.1 - 4.9 7.3 9.5 27 4.9 0.2 2.6 2 0 0 2 2 2 0 RING-type zinc-finger PDZ PF00595.24 EKX31360.1 - 1.4e-25 89.5 0.9 6.3e-12 45.7 0.0 4.8 4 0 0 4 4 4 3 PDZ domain PDZ_6 PF17820.1 EKX31360.1 - 4.7e-23 80.8 7.4 7.1e-13 48.2 0.5 4.9 4 0 0 4 4 4 3 PDZ domain PDZ_2 PF13180.6 EKX31360.1 - 7.5e-18 64.6 11.0 4.8e-07 30.0 0.1 5.2 5 0 0 5 5 5 4 PDZ domain Tricorn_PDZ PF14685.6 EKX31360.1 - 4e-07 29.9 7.8 0.011 15.7 0.1 5.4 4 1 0 4 4 4 3 Tricorn protease PDZ domain Sec34 PF04136.15 EKX31360.1 - 0.0023 17.8 3.2 0.0023 17.8 3.2 12.3 9 3 3 13 13 13 3 Sec34-like family DUF5082 PF16888.5 EKX31360.1 - 0.0035 17.6 4.4 0.0035 17.6 4.4 12.3 6 5 5 13 13 13 1 Domain of unknown function (DUF5082) Cytochrom_B561 PF03188.16 EKX31361.1 - 7.3e-14 52.1 4.3 7.3e-14 52.1 4.3 1.4 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 EKX31361.1 - 0.0038 17.4 6.9 0.0092 16.1 6.9 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4079) Glyco_transf_49 PF13896.6 EKX31362.1 - 2.6e-25 89.5 3.6 4.2e-11 42.8 1.0 3.1 2 1 0 2 2 2 2 Glycosyl-transferase for dystroglycan fn3 PF00041.21 EKX31362.1 - 0.0028 18.0 0.0 2.7 8.4 0.0 2.7 2 0 0 2 2 2 2 Fibronectin type III domain TIM PF00121.18 EKX31363.1 - 1.5e-56 191.5 0.0 1.7e-56 191.3 0.0 1.1 1 0 0 1 1 1 1 Triosephosphate isomerase DUF4692 PF15763.5 EKX31364.1 - 0.023 15.2 1.0 0.034 14.6 1.0 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Macoilin PF09726.9 EKX31364.1 - 0.12 10.9 1.7 0.14 10.7 1.7 1.0 1 0 0 1 1 1 0 Macoilin family SPT16 PF08644.11 EKX31364.1 - 0.12 12.5 0.1 0.18 11.9 0.1 1.2 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) DUF4769 PF15992.5 EKX31364.1 - 0.37 10.5 3.6 0.51 10.1 1.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4769) PRKG1_interact PF15898.5 EKX31365.1 - 0.079 13.9 17.6 0.11 13.4 2.0 2.6 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF724 PF05266.14 EKX31365.1 - 1.9 8.3 11.9 1.1 9.1 5.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DivIC PF04977.15 EKX31365.1 - 2.9 7.7 13.5 2.6 7.9 0.9 3.1 1 1 2 3 3 3 0 Septum formation initiator RVT_1 PF00078.27 EKX31366.1 - 1.7e-06 27.7 0.0 7.1e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.32 EKX31367.1 - 4.4e-10 40.0 8.3 0.39 11.7 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX31367.1 - 0.00059 20.1 0.2 0.021 15.1 0.0 2.9 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain YkyA PF10368.9 EKX31368.1 - 0.049 13.3 13.4 0.25 11.0 1.4 3.1 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein TPR_4 PF07721.14 EKX31368.1 - 0.081 13.6 0.9 0.45 11.3 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4398 PF14346.6 EKX31368.1 - 0.65 10.7 18.8 0.31 11.7 2.2 3.4 3 2 1 4 4 4 0 Domain of unknown function (DUF4398) DUF1663 PF07909.11 EKX31368.1 - 5 5.8 11.9 10 4.8 11.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1663) FUSC PF04632.12 EKX31368.1 - 7.2 5.0 5.8 1.1 7.7 1.1 1.8 1 1 1 2 2 2 0 Fusaric acid resistance protein family Nkap_C PF06047.11 EKX31369.1 - 6.1e-43 145.1 3.4 7.3e-43 144.8 3.4 1.1 1 0 0 1 1 1 1 NF-kappa-B-activating protein C-terminal domain Glycoprotein_B PF00606.18 EKX31369.1 - 0.097 12.1 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B ectodomain Ank_4 PF13637.6 EKX31370.1 - 1.4e-16 60.6 0.1 2e-05 25.0 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX31370.1 - 8e-14 51.5 2.1 1.8e-08 34.5 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX31370.1 - 1.7e-13 50.3 0.9 0.0024 18.2 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 EKX31370.1 - 3.6e-13 49.9 0.4 1.5e-07 31.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX31370.1 - 1.4e-09 37.4 0.2 0.0072 16.8 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Pfg27 PF09216.10 EKX31371.1 - 0.022 14.6 0.3 0.057 13.3 0.3 1.7 1 0 0 1 1 1 0 Pfg27 PRD PF00874.20 EKX31371.1 - 0.21 11.9 2.3 4.5 7.6 0.0 3.5 4 0 0 4 4 4 0 PRD domain Baculo_PEP_C PF04513.12 EKX31371.1 - 1.5 8.9 4.8 36 4.4 1.0 3.9 3 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5388 PF17363.2 EKX31371.1 - 4 7.7 6.8 10 6.4 0.6 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF5388) HMMR_N PF15905.5 EKX31371.1 - 7.5 5.9 42.3 0.62 9.5 16.7 3.4 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Pkinase PF00069.25 EKX31372.1 - 1.2e-34 119.9 0.0 1.4e-34 119.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX31372.1 - 1.9e-16 60.2 0.0 2e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX31372.1 - 8.3e-06 24.8 0.0 9.2e-06 24.7 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EKX31372.1 - 0.0013 18.1 0.0 0.0016 17.8 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EKX31372.1 - 0.03 13.9 0.0 0.04 13.5 0.0 1.1 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EKX31372.1 - 0.12 12.3 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EKX31372.1 - 0.16 11.6 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 EKX31372.1 - 0.17 11.4 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL CIMR PF00878.18 EKX31373.1 - 0.00016 21.8 0.0 0.00053 20.1 0.0 1.9 1 1 0 1 1 1 1 Cation-independent mannose-6-phosphate receptor repeat DUF3808 PF10300.9 EKX31375.1 - 1.2e-30 106.7 1.5 5.5e-30 104.5 1.5 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 EKX31375.1 - 0.0025 17.8 7.4 2 8.7 0.3 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX31375.1 - 0.0069 16.9 6.7 0.59 10.7 0.3 4.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX31375.1 - 2.1 8.7 15.3 1.1 9.6 0.4 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX31375.1 - 9.4 7.1 9.7 22 5.9 0.1 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat GYF PF02213.16 EKX31376.1 - 2e-08 33.7 0.0 5.1e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 GYF domain DUF4043 PF13252.6 EKX31378.1 - 0.041 13.0 0.1 0.057 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4043) DnaJ_C PF01556.18 EKX31379.1 - 1.4e-41 142.0 0.2 2e-41 141.5 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EKX31379.1 - 4.6e-27 93.9 4.7 7.9e-27 93.2 4.7 1.4 1 0 0 1 1 1 1 DnaJ domain SAM_MT PF04445.13 EKX31380.1 - 4.5e-29 101.5 0.0 7.3e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Cons_hypoth95 PF03602.15 EKX31380.1 - 0.0005 19.8 0.0 0.00076 19.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 zf-RRPl_C4 PF17026.5 EKX31383.1 - 0.18 11.9 3.3 0.16 12.1 0.9 2.2 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type DUF4548 PF15081.6 EKX31383.1 - 1.6 8.6 4.1 5.2 6.9 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4548) Beta-lactamase PF00144.24 EKX31384.1 - 1.8e-29 103.1 0.0 2.8e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase LRR_6 PF13516.6 EKX31385.1 - 9.5e-15 53.3 17.6 0.0052 16.7 0.0 7.4 7 0 0 7 7 7 5 Leucine Rich repeat LRR_8 PF13855.6 EKX31385.1 - 0.0056 16.4 15.5 0.79 9.5 5.5 4.7 2 2 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 EKX31385.1 - 0.014 15.8 19.8 0.74 10.3 3.1 4.7 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) OapA PF04225.12 EKX31385.1 - 0.056 13.6 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Opacity-associated protein A LysM-like domain NESP55 PF06390.12 EKX31385.1 - 0.42 10.2 2.7 0.65 9.5 2.7 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) LRR_1 PF00560.33 EKX31385.1 - 1.8 9.5 16.5 25 6.0 0.0 6.6 5 3 2 7 7 7 0 Leucine Rich Repeat Asp5 PF17000.5 EKX31386.1 - 0.0029 17.7 0.1 0.0058 16.7 0.1 1.5 1 0 0 1 1 1 1 Accessory secretory protein Sec, Asp5 BHD_1 PF10403.9 EKX31386.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 1 HalX PF08663.10 EKX31387.1 - 0.031 14.6 0.3 0.031 14.6 0.3 2.0 2 0 0 2 2 2 0 HalX domain FlxA PF14282.6 EKX31387.1 - 0.13 12.3 0.1 0.13 12.3 0.1 1.5 2 0 0 2 2 2 0 FlxA-like protein DUF1938 PF09153.10 EKX31387.1 - 0.2 11.8 0.0 16 5.6 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1938) FMN_dh PF01070.18 EKX31388.1 - 0.16 11.0 1.9 0.21 10.6 1.8 1.4 1 1 0 1 1 1 0 FMN-dependent dehydrogenase DUF1216 PF06746.11 EKX31388.1 - 0.2 11.7 9.7 0.32 11.0 8.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1216) PRKG1_interact PF15898.5 EKX31388.1 - 0.39 11.6 17.6 0.35 11.8 1.2 3.1 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain Spc7 PF08317.11 EKX31388.1 - 6.2 5.6 18.1 10 4.9 14.7 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Thioredoxin PF00085.20 EKX31389.1 - 1.2e-23 83.1 0.0 1.3e-23 83.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EKX31389.1 - 1.1e-07 32.2 0.1 3.2e-06 27.5 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 EKX31389.1 - 0.00033 20.6 0.0 0.0004 20.3 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 EKX31389.1 - 0.0012 18.3 0.0 0.0016 17.8 0.0 1.3 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EKX31389.1 - 0.0071 16.3 0.0 0.0075 16.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EKX31389.1 - 0.0071 16.7 0.0 0.32 11.4 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.6 EKX31389.1 - 0.022 14.9 0.0 0.035 14.3 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like DSBA PF01323.20 EKX31389.1 - 0.025 14.4 0.2 3.3 7.4 0.3 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EKX31389.1 - 0.17 12.0 0.1 3 8.0 0.2 2.0 1 1 1 2 2 2 0 Thioredoxin DUF4214 PF13946.6 EKX31390.1 - 0.0014 18.6 0.0 0.0049 16.9 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4214) Synaptobrevin PF00957.21 EKX31391.1 - 6.1e-30 102.9 5.0 1.2e-29 101.9 5.0 1.5 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EKX31391.1 - 1.6e-05 24.8 0.1 2.7e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain RIFIN PF02009.16 EKX31391.1 - 0.00079 19.4 4.2 0.0011 19.0 4.2 1.2 1 0 0 1 1 1 1 Rifin Fzo_mitofusin PF04799.13 EKX31391.1 - 0.00082 19.0 2.7 0.0017 17.9 2.7 1.6 1 1 0 1 1 1 1 fzo-like conserved region LemA PF04011.12 EKX31391.1 - 0.015 15.2 0.9 0.031 14.1 0.7 1.5 1 1 0 1 1 1 0 LemA family EMP24_GP25L PF01105.24 EKX31391.1 - 0.021 14.8 1.8 0.029 14.3 1.8 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Pox_EPC_I2-L1 PF12575.8 EKX31391.1 - 0.19 12.0 2.8 0.36 11.1 0.3 2.6 3 0 0 3 3 3 0 Poxvirus entry protein complex L1 and I2 SNARE PF05739.19 EKX31391.1 - 0.26 11.3 4.6 0.97 9.5 4.6 2.0 1 0 0 1 1 1 0 SNARE domain Peptidase_C36 PF05415.11 EKX31391.1 - 0.28 11.4 4.4 0.45 10.8 0.2 2.6 3 0 0 3 3 3 0 Beet necrotic yellow vein furovirus-type papain-like endopeptidase NPV_P10 PF05531.12 EKX31391.1 - 1.3 9.6 8.3 0.11 13.0 2.8 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein MCU PF04678.13 EKX31391.1 - 1.9 8.6 7.7 2.5 8.2 7.7 1.4 1 1 0 1 1 1 0 Mitochondrial calcium uniporter TMIE PF16038.5 EKX31391.1 - 3.4 7.6 12.1 0.85 9.5 7.5 2.3 2 0 0 2 2 2 0 TMIE protein Snf7 PF03357.21 EKX31392.1 - 9.1e-29 100.3 21.0 1.4e-28 99.6 21.0 1.3 1 0 0 1 1 1 1 Snf7 COPI_assoc PF08507.10 EKX31392.1 - 0.00078 19.5 0.4 0.0012 18.9 0.4 1.3 1 0 0 1 1 1 1 COPI associated protein Cg6151-P PF10233.9 EKX31392.1 - 0.0076 16.6 0.9 0.013 15.8 0.9 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P TACC_C PF05010.14 EKX31392.1 - 0.055 13.2 15.9 0.02 14.7 13.0 1.7 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal ELYS PF13934.6 EKX31392.1 - 0.059 13.3 2.7 0.091 12.7 2.7 1.3 1 0 0 1 1 1 0 Nuclear pore complex assembly NCD1 PF04904.13 EKX31392.1 - 0.093 12.7 0.6 0.18 11.8 0.6 1.4 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) Miga PF10265.9 EKX31392.1 - 5.6 5.8 10.9 29 3.5 10.4 1.7 1 1 1 2 2 2 0 Mitoguardin Pyr_redox_2 PF07992.14 EKX31393.1 - 2.6e-39 135.2 0.4 3.3e-39 134.9 0.4 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EKX31393.1 - 4e-13 49.7 1.6 3.4e-10 40.3 0.1 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EKX31393.1 - 5.3e-11 42.3 0.4 3.2e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EKX31393.1 - 2.8e-07 30.8 0.0 9e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain FAD_binding_2 PF00890.24 EKX31393.1 - 9.6e-07 28.2 0.8 1.2e-05 24.6 0.1 2.2 1 1 1 2 2 2 1 FAD binding domain DAO PF01266.24 EKX31393.1 - 3.5e-05 23.6 0.8 0.0061 16.2 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EKX31393.1 - 0.00011 21.1 0.3 0.0019 17.0 0.1 2.6 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.7 EKX31393.1 - 0.00035 20.0 1.2 0.00061 19.3 0.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EKX31393.1 - 0.00094 18.5 0.3 0.036 13.4 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EKX31393.1 - 0.0043 16.2 0.2 0.088 11.9 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A K_oxygenase PF13434.6 EKX31393.1 - 0.0045 16.2 0.0 0.37 9.9 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EKX31393.1 - 0.05 12.8 0.4 0.74 9.0 0.0 2.4 2 1 1 3 3 3 0 Thi4 family DUF599 PF04654.12 EKX31394.1 - 1.1e-05 25.0 1.4 1.3e-05 24.8 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF599 DUF5325 PF17259.2 EKX31394.1 - 0.069 13.0 1.0 0.069 13.0 1.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5325) Zn_clus PF00172.18 EKX31395.1 - 1.3e-11 44.4 28.4 5.5e-07 29.6 11.9 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Propep_M14 PF02244.16 EKX31395.1 - 0.07 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Enkurin PF13864.6 EKX31396.1 - 8.9e-28 96.6 7.9 1.3e-27 96.0 7.9 1.3 1 0 0 1 1 1 1 Calmodulin-binding YlqD PF11068.8 EKX31396.1 - 0.053 13.9 1.3 0.053 13.9 1.3 2.4 1 1 1 2 2 2 0 YlqD protein BST2 PF16716.5 EKX31396.1 - 0.32 11.6 8.3 0.092 13.3 1.4 2.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Muted PF14942.6 EKX31396.1 - 0.45 10.9 7.3 1.5 9.2 7.4 1.8 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein AAA_23 PF13476.6 EKX31396.1 - 0.5 10.8 8.2 0.64 10.5 8.2 1.1 1 0 0 1 1 1 0 AAA domain DUF5344 PF17279.2 EKX31396.1 - 1.1 9.8 6.9 1.2 9.7 0.5 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5344) Prefoldin PF02996.17 EKX31396.1 - 1.9 8.4 8.0 0.087 12.7 1.5 2.1 3 1 1 4 4 4 0 Prefoldin subunit ATG16 PF08614.11 EKX31398.1 - 0.026 14.8 0.6 0.026 14.8 0.6 3.6 2 1 2 5 5 5 0 Autophagy protein 16 (ATG16) PKcGMP_CC PF16808.5 EKX31398.1 - 0.027 14.3 0.8 0.13 12.1 0.8 2.3 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SelR PF01641.18 EKX31398.1 - 0.034 14.2 0.0 0.087 12.9 0.0 1.7 1 0 0 1 1 1 0 SelR domain LXG PF04740.12 EKX31398.1 - 0.039 13.6 0.1 1.5 8.5 0.0 3.1 2 1 1 3 3 3 0 LXG domain of WXG superfamily DUF16 PF01519.16 EKX31398.1 - 0.1 13.1 8.5 2.8 8.5 0.5 3.8 3 1 0 3 3 3 0 Protein of unknown function DUF16 DUF641 PF04859.12 EKX31398.1 - 0.17 12.3 2.1 0.75 10.1 0.1 2.7 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) TMPIT PF07851.13 EKX31398.1 - 0.19 11.0 4.5 11 5.2 0.3 3.1 3 0 0 3 3 3 0 TMPIT-like protein COG5 PF10392.9 EKX31398.1 - 0.55 10.4 2.2 7.9 6.7 0.0 3.0 3 1 1 4 4 4 0 Golgi transport complex subunit 5 DUF5082 PF16888.5 EKX31398.1 - 1.1 9.5 4.0 31 4.9 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) LPP PF04728.13 EKX31398.1 - 1.2 9.6 5.1 3.6 8.1 0.2 4.0 5 1 0 5 5 5 0 Lipoprotein leucine-zipper SKA1 PF07160.12 EKX31398.1 - 2.2 8.1 4.9 1.5 8.7 0.1 2.8 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 DUF1664 PF07889.12 EKX31398.1 - 2.5 8.1 9.9 5.6 7.0 0.5 3.7 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) Nsp1_C PF05064.13 EKX31398.1 - 4.6 7.1 9.4 3.7 7.4 1.5 3.4 3 1 0 3 3 3 0 Nsp1-like C-terminal region DUF3450 PF11932.8 EKX31398.1 - 5.4 6.2 12.5 14 4.9 1.5 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) Tad PF13400.6 EKX31399.1 - 0.13 12.6 0.3 0.23 11.8 0.3 1.5 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like MaAIMP_sms PF16951.5 EKX31399.1 - 0.14 11.9 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 Putative methionine and alanine importer, small subunit Histone PF00125.24 EKX31400.1 - 3.4e-20 72.7 0.0 4.6e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EKX31400.1 - 8.8e-13 47.8 1.6 1.7e-12 46.9 1.6 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EKX31400.1 - 0.011 16.0 0.0 0.015 15.6 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ephrin_rec_like PF07699.13 EKX31401.1 - 0.00024 20.8 23.7 0.0012 18.5 6.8 6.6 3 2 4 7 7 7 5 Putative ephrin-receptor like TBP PF00352.21 EKX31405.1 - 4.4e-33 113.1 0.0 2.1e-15 56.4 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EKX31405.1 - 7.5e-06 26.0 0.0 0.11 12.6 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) KLRAQ PF10205.9 EKX31407.1 - 0.0071 16.6 0.9 1.5 9.1 0.1 2.1 1 1 1 2 2 2 2 Predicted coiled-coil domain-containing protein Tektin PF03148.14 EKX31407.1 - 0.0073 15.1 0.5 0.0092 14.8 0.5 1.0 1 0 0 1 1 1 1 Tektin family Pterin_bind PF00809.22 EKX31407.1 - 0.015 15.0 0.1 0.016 14.9 0.1 1.1 1 0 0 1 1 1 0 Pterin binding enzyme DUF16 PF01519.16 EKX31407.1 - 0.028 14.9 0.7 0.054 14.0 0.3 1.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF948 PF06103.11 EKX31407.1 - 0.031 14.5 1.8 4.9 7.5 1.8 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Phage_Gp23 PF10669.9 EKX31407.1 - 0.057 13.8 3.3 0.058 13.7 1.5 1.5 1 1 1 2 2 2 0 Protein gp23 (Bacteriophage A118) zf-C4H2 PF10146.9 EKX31407.1 - 0.24 11.7 0.7 0.28 11.5 0.7 1.0 1 0 0 1 1 1 0 Zinc finger-containing protein Tcp11 PF05794.13 EKX31408.1 - 2.5e-31 109.2 0.8 1.4e-30 106.8 0.8 2.2 1 1 0 1 1 1 1 T-complex protein 11 DEK_C PF08766.11 EKX31409.1 - 0.093 12.7 1.4 1.8 8.6 1.5 2.4 1 1 0 1 1 1 0 DEK C terminal domain Casc1_N PF15927.5 EKX31410.1 - 0.55 9.9 13.0 1 9.0 13.0 1.4 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus EamA PF00892.20 EKX31411.1 - 1e-08 35.5 19.2 0.00033 20.8 8.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EKX31411.1 - 0.0018 17.7 13.2 0.0023 17.3 13.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family RE_XamI PF09572.10 EKX31412.1 - 0.069 12.8 0.0 0.084 12.5 0.0 1.1 1 0 0 1 1 1 0 XamI restriction endonuclease DUF2635 PF10948.8 EKX31415.1 - 1e-06 28.4 19.4 7.7 6.3 0.7 7.2 1 1 7 8 8 8 8 Protein of unknown function (DUF2635) PARP PF00644.20 EKX31416.1 - 2.1e-17 63.4 0.0 4.3e-17 62.3 0.0 1.5 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Exotox-A_cataly PF09009.10 EKX31416.1 - 0.068 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Exotoxin A catalytic Phage_integrase PF00589.22 EKX31416.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Phage integrase family ShK PF01549.24 EKX31421.1 - 4.7e-06 27.0 7.6 1.1e-05 25.8 7.6 1.7 1 0 0 1 1 1 1 ShK domain-like Methyltransf_23 PF13489.6 EKX31421.1 - 0.029 14.2 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L19 PF01245.20 EKX31423.1 - 7.3e-20 71.0 0.2 1.1e-19 70.4 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 DUF974 PF06159.13 EKX31425.1 - 3.9e-27 95.6 0.0 4.9e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) DUF5331 PF17265.2 EKX31430.1 - 0.047 13.4 2.9 0.42 10.4 0.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5331) ALMT PF11744.8 EKX31430.1 - 3.8 6.2 14.1 4.2 6.1 14.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Filament PF00038.21 EKX31431.1 - 0.00036 20.2 0.8 0.00036 20.2 0.8 2.1 2 0 0 2 2 2 1 Intermediate filament protein Spc7 PF08317.11 EKX31431.1 - 0.0012 17.8 8.3 0.0046 15.9 0.4 3.0 1 1 2 3 3 3 2 Spc7 kinetochore protein DUF1664 PF07889.12 EKX31431.1 - 0.0017 18.4 5.3 0.16 12.0 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) DUF812 PF05667.11 EKX31431.1 - 0.002 17.1 13.5 0.054 12.4 0.8 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF812) FlaC_arch PF05377.11 EKX31431.1 - 0.0022 18.4 2.3 0.12 12.8 0.2 3.4 2 2 1 3 3 3 1 Flagella accessory protein C (FlaC) Laminin_II PF06009.12 EKX31431.1 - 0.0033 17.4 0.1 0.033 14.2 0.0 2.3 1 1 1 2 2 2 1 Laminin Domain II PhageMin_Tail PF10145.9 EKX31431.1 - 0.0039 17.1 0.1 0.51 10.2 0.1 2.6 1 1 0 1 1 1 1 Phage-related minor tail protein MscS_porin PF12795.7 EKX31431.1 - 0.0058 16.2 2.3 0.0058 16.2 2.3 2.4 2 1 0 2 2 2 1 Mechanosensitive ion channel porin domain DUF4715 PF15835.5 EKX31431.1 - 0.0088 16.1 7.8 0.13 12.4 4.4 3.0 1 1 2 3 3 3 1 Domain of unknown function (DUF4715) efThoc1 PF11957.8 EKX31431.1 - 0.013 14.2 0.1 0.013 14.2 0.1 1.9 2 0 0 2 2 2 0 THO complex subunit 1 transcription elongation factor DUF5082 PF16888.5 EKX31431.1 - 0.015 15.6 10.3 0.7 10.2 3.2 3.1 2 2 0 2 2 2 0 Domain of unknown function (DUF5082) NPV_P10 PF05531.12 EKX31431.1 - 0.026 15.0 3.8 0.41 11.2 0.1 3.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein ING PF12998.7 EKX31431.1 - 0.056 14.0 6.4 0.045 14.3 2.9 2.1 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding AAA_13 PF13166.6 EKX31431.1 - 0.06 12.0 3.3 0.63 8.6 0.1 2.2 1 1 1 2 2 2 0 AAA domain COG2 PF06148.11 EKX31431.1 - 0.062 13.4 3.6 0.078 13.1 0.7 2.4 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TMPIT PF07851.13 EKX31431.1 - 0.16 11.2 4.0 0.19 10.9 0.6 2.0 2 0 0 2 2 2 0 TMPIT-like protein DUF2312 PF10073.9 EKX31431.1 - 0.33 10.6 14.2 6.5 6.5 2.3 4.4 2 1 3 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2312) Bacillus_HBL PF05791.11 EKX31431.1 - 0.39 10.5 9.1 4.8 7.0 0.4 3.7 1 1 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) ParB PF08775.10 EKX31431.1 - 0.61 10.6 6.7 0.82 10.2 3.8 2.4 2 1 0 2 2 2 0 ParB family DUF948 PF06103.11 EKX31431.1 - 0.65 10.3 1.8 8.9 6.6 0.2 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Vps51 PF08700.11 EKX31431.1 - 0.76 9.9 6.1 3.9 7.6 3.7 3.0 2 1 0 2 2 2 0 Vps51/Vps67 DivIC PF04977.15 EKX31431.1 - 0.79 9.5 5.4 0.59 9.9 1.6 2.4 2 1 0 2 2 2 0 Septum formation initiator DUF4407 PF14362.6 EKX31431.1 - 1.7 8.0 7.5 5.4 6.3 7.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 EKX31431.1 - 3.9 7.5 15.3 3.3 7.8 8.1 2.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Presenilin PF01080.17 EKX31431.1 - 8.1 5.1 4.9 11 4.6 4.9 1.2 1 0 0 1 1 1 0 Presenilin DUF2203 PF09969.9 EKX31431.1 - 9.9 6.9 11.7 1.3e+02 3.3 7.1 3.3 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Filament PF00038.21 EKX31433.1 - 3.5e-06 26.8 5.6 0.0004 20.1 0.5 2.1 1 1 2 3 3 3 2 Intermediate filament protein Spc7 PF08317.11 EKX31433.1 - 1e-05 24.6 8.8 0.0002 20.4 0.2 2.7 1 1 1 2 2 2 1 Spc7 kinetochore protein Laminin_II PF06009.12 EKX31433.1 - 1.8e-05 24.8 0.1 0.0016 18.5 0.0 2.5 1 1 3 4 4 4 3 Laminin Domain II DUF1664 PF07889.12 EKX31433.1 - 7.7e-05 22.7 5.4 0.0012 18.9 0.5 2.4 1 1 2 3 3 3 2 Protein of unknown function (DUF1664) DUF812 PF05667.11 EKX31433.1 - 0.00012 21.1 13.0 0.0026 16.7 1.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF812) NPV_P10 PF05531.12 EKX31433.1 - 0.00015 22.2 1.4 0.2 12.1 0.2 2.8 1 1 1 2 2 2 2 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 EKX31433.1 - 0.00024 21.4 5.6 0.12 12.8 0.4 3.6 2 2 1 3 3 3 2 Flagella accessory protein C (FlaC) MscS_porin PF12795.7 EKX31433.1 - 0.00038 20.1 2.2 0.0034 17.0 0.1 2.8 1 1 2 3 3 3 1 Mechanosensitive ion channel porin domain HAP1_N PF04849.13 EKX31433.1 - 0.00048 19.4 1.3 0.00065 19.0 0.0 1.8 1 1 1 2 2 2 1 HAP1 N-terminal conserved region Laminin_I PF06008.14 EKX31433.1 - 0.00081 19.2 3.4 0.0014 18.4 0.6 2.0 1 1 1 2 2 2 1 Laminin Domain I ATG16 PF08614.11 EKX31433.1 - 0.001 19.3 8.4 0.0052 17.0 0.3 2.4 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) ADIP PF11559.8 EKX31433.1 - 0.0056 16.8 0.4 3.1 7.9 0.0 2.5 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding DUF5082 PF16888.5 EKX31433.1 - 0.0057 16.9 11.2 0.96 9.7 6.1 3.6 1 1 1 2 2 2 1 Domain of unknown function (DUF5082) She9_MDM33 PF05546.11 EKX31433.1 - 0.0062 16.4 0.3 0.012 15.5 0.2 1.5 1 1 0 1 1 1 1 She9 / Mdm33 family DUF4715 PF15835.5 EKX31433.1 - 0.0072 16.4 10.6 0.068 13.2 4.4 3.5 1 1 2 3 3 3 1 Domain of unknown function (DUF4715) DASH_Duo1 PF08651.10 EKX31433.1 - 0.014 15.2 0.1 6.6 6.6 0.0 3.3 1 1 1 2 2 2 0 DASH complex subunit Duo1 CENP-F_leu_zip PF10473.9 EKX31433.1 - 0.015 15.3 1.4 0.015 15.3 1.4 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMPIT PF07851.13 EKX31433.1 - 0.016 14.5 1.2 0.016 14.5 1.2 1.9 1 1 1 2 2 2 0 TMPIT-like protein Fez1 PF06818.15 EKX31433.1 - 0.018 15.5 2.9 0.018 15.5 2.9 2.2 1 1 1 2 2 2 0 Fez1 MtrG PF04210.13 EKX31433.1 - 0.019 14.8 1.5 4.5 7.2 0.4 2.7 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G UPF0242 PF06785.11 EKX31433.1 - 0.02 15.0 0.5 0.02 15.0 0.5 2.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Prefoldin_2 PF01920.20 EKX31433.1 - 0.022 14.7 2.1 0.022 14.7 2.1 3.6 1 1 1 3 3 3 0 Prefoldin subunit I_LWEQ PF01608.17 EKX31433.1 - 0.031 14.5 2.7 0.078 13.2 2.7 1.7 1 0 0 1 1 1 0 I/LWEQ domain COG2 PF06148.11 EKX31433.1 - 0.034 14.2 4.2 0.16 12.1 2.0 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TolA_bind_tri PF16331.5 EKX31433.1 - 0.043 13.9 0.7 0.043 13.9 0.7 2.9 1 1 2 3 3 3 0 TolA binding protein trimerisation AAA_13 PF13166.6 EKX31433.1 - 0.044 12.4 5.5 0.092 11.4 0.1 2.2 1 1 1 2 2 2 0 AAA domain Baculo_PEP_C PF04513.12 EKX31433.1 - 0.048 13.7 0.0 0.089 12.8 0.0 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus IFT57 PF10498.9 EKX31433.1 - 0.049 12.6 8.0 0.12 11.3 7.9 1.7 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 WXG100 PF06013.12 EKX31433.1 - 0.061 13.6 4.5 5.9 7.2 0.1 3.3 1 1 2 3 3 3 0 Proteins of 100 residues with WXG ABC_tran_CTD PF16326.5 EKX31433.1 - 0.074 13.3 3.0 2.7 8.3 0.4 3.5 1 1 2 3 3 2 0 ABC transporter C-terminal domain DUF4349 PF14257.6 EKX31433.1 - 0.095 12.1 3.4 91 2.4 0.1 3.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4349) UPF0561 PF10573.9 EKX31433.1 - 0.096 12.8 1.3 0.16 12.1 1.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 Macoilin PF09726.9 EKX31433.1 - 0.13 10.8 10.1 0.17 10.4 10.1 1.1 1 0 0 1 1 1 0 Macoilin family DUF4407 PF14362.6 EKX31433.1 - 0.14 11.5 5.9 0.19 11.0 5.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Occludin_ELL PF07303.13 EKX31433.1 - 0.14 12.9 1.7 0.49 11.1 0.4 2.3 2 0 0 2 2 2 0 Occludin homology domain Bacillus_HBL PF05791.11 EKX31433.1 - 0.16 11.7 11.5 0.13 12.1 4.3 3.5 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF948 PF06103.11 EKX31433.1 - 0.22 11.8 3.1 12 6.2 3.1 2.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Syntaxin_2 PF14523.6 EKX31433.1 - 0.47 10.8 6.5 1.6 9.1 6.5 2.2 1 1 0 1 1 1 0 Syntaxin-like protein DUF2312 PF10073.9 EKX31433.1 - 1.3 8.7 15.1 4.6 6.9 1.6 4.2 2 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2312) Coa1 PF08695.10 EKX31433.1 - 1.7 8.4 6.9 7.4 6.4 0.8 2.6 1 1 1 2 2 2 0 Cytochrome oxidase complex assembly protein 1 FAM76 PF16046.5 EKX31433.1 - 3.7 6.8 7.9 5.3 6.3 7.0 1.7 1 1 0 1 1 1 0 FAM76 protein PEARLI-4 PF05278.12 EKX31433.1 - 4.9 6.7 12.0 0.13 11.8 0.9 2.3 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF2203 PF09969.9 EKX31433.1 - 6.8 7.4 11.2 44 4.8 7.3 3.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Cauli_DNA-bind PF03310.13 EKX31433.1 - 7.3 6.7 8.9 22 5.1 5.8 2.9 2 1 0 2 2 2 0 Caulimovirus DNA-binding protein NOA36 PF06524.12 EKX31436.1 - 0.058 12.7 13.2 0.097 12.0 13.2 1.3 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 EKX31436.1 - 0.094 13.0 13.3 0.23 11.7 13.3 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PPP4R2 PF09184.11 EKX31436.1 - 0.096 12.3 9.3 0.14 11.7 9.3 1.3 1 0 0 1 1 1 0 PPP4R2 RXT2_N PF08595.11 EKX31436.1 - 0.28 11.2 6.5 0.72 9.9 6.5 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.14 EKX31436.1 - 0.93 7.7 9.3 1.8 6.8 9.3 1.4 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 EKX31436.1 - 3.6 6.9 14.4 1.2 8.5 11.6 1.7 2 0 0 2 2 2 0 SDA1 DUF2457 PF10446.9 EKX31436.1 - 3.7 6.6 20.1 6.6 5.8 20.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.12 EKX31436.1 - 3.8 7.2 18.2 0.078 12.7 11.5 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RRN3 PF05327.11 EKX31436.1 - 3.9 5.9 6.8 5.4 5.4 6.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BSP_II PF05432.11 EKX31436.1 - 5.4 6.6 17.3 9.6 5.8 17.3 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CENP-B_dimeris PF09026.10 EKX31436.1 - 7.2 7.1 24.7 22 5.5 24.7 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.13 EKX31436.1 - 7.5 6.4 13.4 1.6 8.5 9.4 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region PBP1_TM PF14812.6 EKX31436.1 - 7.8 6.9 15.3 26 5.2 13.3 3.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HC2 PF07382.11 EKX31437.1 - 0.0005 20.2 44.8 0.00062 19.9 44.8 1.1 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 SUIM_assoc PF16619.5 EKX31440.1 - 0.018 15.1 10.6 0.036 14.1 10.6 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 EKX31440.1 - 0.05 13.6 7.7 0.053 13.5 7.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 EKX31440.1 - 0.18 12.8 3.8 0.28 12.2 3.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 EKX31440.1 - 0.5 10.0 12.0 0.63 9.6 12.0 1.1 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 EKX31440.1 - 0.69 8.6 2.6 0.68 8.6 2.6 1.1 1 0 0 1 1 1 0 Presenilin DUF5345 PF17280.2 EKX31440.1 - 2.6 8.1 6.5 5 7.2 6.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5345) Androgen_recep PF02166.16 EKX31440.1 - 3.1 6.6 9.5 3.9 6.2 9.5 1.2 1 0 0 1 1 1 0 Androgen receptor DUF4220 PF13968.6 EKX31441.1 - 0.18 11.1 0.2 0.33 10.3 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4220) RapH_N PF18801.1 EKX31442.1 - 0.13 12.4 1.9 7.5 6.7 0.1 2.5 2 0 0 2 2 2 0 response regulator aspartate phosphatase H, N terminal DUF922 PF06037.11 EKX31443.1 - 0.059 13.2 0.6 0.074 12.8 0.6 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) EMP70 PF02990.16 EKX31443.1 - 0.15 10.7 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 Proteasome PF00227.26 EKX31444.1 - 2.5e-40 138.0 0.0 2.9e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Abhydrolase_2 PF02230.16 EKX31445.1 - 6.9e-35 120.8 0.0 1.1e-24 87.5 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.13 EKX31445.1 - 1.5e-08 34.5 0.0 2.4e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 EKX31445.1 - 9.7e-08 31.6 0.2 0.0043 16.4 0.0 2.7 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EKX31445.1 - 5.5e-07 29.5 0.0 8.2e-05 22.4 0.0 2.6 2 1 1 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EKX31445.1 - 0.00035 21.3 3.4 0.00035 21.3 3.4 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EKX31445.1 - 0.0072 16.4 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein DLH PF01738.18 EKX31445.1 - 0.0089 15.6 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.12 EKX31445.1 - 0.012 14.3 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF2974 PF11187.8 EKX31445.1 - 0.013 15.0 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Thioesterase PF00975.20 EKX31445.1 - 0.019 15.1 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.13 EKX31445.1 - 0.029 14.2 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 EKX31445.1 - 0.068 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.21 EKX31445.1 - 0.085 12.3 0.0 2.8 7.4 0.0 2.2 1 1 1 2 2 2 0 Prolyl oligopeptidase family ANF_receptor PF01094.28 EKX31446.1 - 1e-18 67.6 0.0 7.6e-18 64.7 0.0 2.2 1 1 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 EKX31446.1 - 1.1e-06 28.6 0.2 1.7e-06 28.0 0.2 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Insulin_TMD PF17870.1 EKX31446.1 - 0.15 12.2 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment AAA_lid_10 PF17872.1 EKX31447.1 - 0.0032 17.5 2.2 0.011 15.9 2.2 1.9 1 0 0 1 1 1 1 AAA lid domain DUF1664 PF07889.12 EKX31447.1 - 0.0043 17.1 4.4 0.0043 17.1 4.4 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF1664) DASH_Duo1 PF08651.10 EKX31447.1 - 4.1 7.3 8.2 2 8.2 0.6 3.2 3 0 0 3 3 3 0 DASH complex subunit Duo1 TPR_17 PF13431.6 EKX31450.1 - 1.3e-31 106.6 1.8 0.00044 20.4 0.0 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 EKX31450.1 - 2.7e-25 87.1 1.6 0.0024 17.6 0.0 7.5 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.17 EKX31450.1 - 1.1e-23 81.4 9.2 0.016 15.3 0.0 8.1 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.6 EKX31450.1 - 3.5e-23 80.3 25.9 0.048 14.5 0.0 8.6 2 2 7 9 9 8 8 Tetratricopeptide repeat TPR_11 PF13414.6 EKX31450.1 - 8.7e-23 79.7 0.0 0.00069 19.2 0.0 7.5 5 2 2 7 7 7 4 TPR repeat TPR_12 PF13424.6 EKX31450.1 - 7.9e-22 77.3 17.8 0.00011 22.5 2.3 6.0 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 EKX31450.1 - 1.8e-21 74.5 1.7 6.1e-05 22.9 0.0 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 EKX31450.1 - 2.5e-18 66.3 18.4 2.8e-05 24.5 6.2 6.3 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 EKX31450.1 - 7.4e-17 61.7 20.2 0.00045 20.8 0.7 6.7 2 2 6 8 8 8 7 Tetratricopeptide repeat TPR_7 PF13176.6 EKX31450.1 - 7.5e-16 56.9 15.0 0.019 14.9 0.0 8.2 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 EKX31450.1 - 1.9e-12 47.1 20.0 0.00032 20.8 0.0 4.9 3 2 2 5 5 5 5 Tetratricopeptide repeat Coatomer_E PF04733.14 EKX31450.1 - 2.7e-09 36.9 5.5 0.0098 15.3 0.1 4.0 3 1 1 4 4 4 3 Coatomer epsilon subunit ANAPC3 PF12895.7 EKX31450.1 - 6.5e-07 29.5 4.3 0.12 12.6 0.0 3.7 2 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EKX31450.1 - 8.1e-06 25.5 27.9 0.031 14.2 0.2 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX31450.1 - 7.2e-05 23.2 14.0 0.033 14.8 0.1 7.0 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 EKX31450.1 - 0.00022 20.5 11.6 0.0039 16.4 3.3 4.3 1 1 2 4 4 4 1 Tetratricopeptide repeat DUF4071 PF13281.6 EKX31450.1 - 0.014 14.5 0.2 3.8 6.5 0.0 3.3 2 1 2 4 4 4 0 Domain of unknown function (DUF4071) SNAP PF14938.6 EKX31450.1 - 0.027 13.9 1.9 0.21 11.0 0.1 2.9 2 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP NARP1 PF12569.8 EKX31450.1 - 0.027 13.4 4.7 0.099 11.5 0.1 2.7 1 1 2 3 3 3 0 NMDA receptor-regulated protein 1 Wzy_C_2 PF11846.8 EKX31450.1 - 0.71 9.8 5.7 7.3 6.5 1.8 3.2 2 1 2 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal Sel1 PF08238.12 EKX31450.1 - 4.3 8.2 7.2 17 6.2 0.1 4.9 6 0 0 6 6 5 0 Sel1 repeat RICH PF05062.12 EKX31452.1 - 0.042 14.2 0.7 0.062 13.7 0.7 1.3 1 0 0 1 1 1 0 RICH domain HAUS-augmin3 PF14932.6 EKX31452.1 - 0.058 13.0 0.8 0.74 9.4 1.4 1.9 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 ABC1 PF03109.16 EKX31453.1 - 1.8e-31 108.8 0.0 4.5e-31 107.5 0.0 1.7 2 0 0 2 2 2 1 ABC1 family APH PF01636.23 EKX31453.1 - 0.0019 18.2 0.6 0.03 14.2 0.6 2.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family MORN PF02493.20 EKX31454.1 - 1.3e-50 166.4 67.2 2.4e-06 27.1 1.6 11.2 11 0 0 11 11 11 11 MORN repeat HEAT_2 PF13646.6 EKX31455.1 - 5.8e-05 23.4 2.2 5.8e-05 23.4 2.2 3.8 2 1 3 5 5 5 2 HEAT repeats HEAT PF02985.22 EKX31455.1 - 0.00013 21.9 1.9 0.013 15.7 0.3 3.4 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 EKX31455.1 - 0.00066 20.1 3.3 0.00066 20.1 3.3 3.7 3 1 1 4 4 4 2 HEAT-like repeat SelA PF03841.13 EKX31455.1 - 0.0074 15.3 1.8 0.045 12.7 0.6 2.6 3 0 0 3 3 3 1 L-seryl-tRNA selenium transferase Chalcone PF02431.15 EKX31455.1 - 0.009 15.4 0.2 0.016 14.6 0.2 1.4 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Arm PF00514.23 EKX31455.1 - 0.8 9.8 3.7 31 4.8 0.0 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat CK_II_beta PF01214.18 EKX31456.1 - 1.8e-59 200.6 0.1 2e-59 200.5 0.1 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit RNA_POL_M_15KD PF02150.16 EKX31456.1 - 0.02 14.8 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit cNMP_binding PF00027.29 EKX31457.1 - 8e-06 25.8 0.0 2.2e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain DUF3160 PF11369.8 EKX31457.1 - 0.012 14.1 0.7 0.017 13.6 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) MFAP1 PF06991.11 EKX31457.1 - 0.029 14.2 10.7 0.043 13.7 10.7 1.2 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing TniQ PF06527.11 EKX31457.1 - 0.2 12.4 1.5 0.32 11.7 1.5 1.4 1 0 0 1 1 1 0 TniQ DUF5003 PF16394.5 EKX31458.1 - 0.2 10.8 0.0 0.32 10.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5003) Arm PF00514.23 EKX31459.1 - 3.5e-07 30.0 7.2 0.0046 17.0 0.1 5.2 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat zf-C3HC4_3 PF13920.6 EKX31459.1 - 6.5e-05 22.7 14.6 0.00012 21.9 14.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Atx10homo_assoc PF09759.9 EKX31459.1 - 0.094 12.7 4.1 0.15 12.1 0.0 3.2 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain Yip1 PF04893.17 EKX31460.1 - 3.3e-10 40.0 14.2 8e-10 38.7 14.0 1.7 1 1 0 1 1 1 1 Yip1 domain PDZ_6 PF17820.1 EKX31461.1 - 1.2e-09 37.9 0.1 7.5e-06 25.7 0.0 3.2 2 1 0 2 2 2 2 PDZ domain PDZ PF00595.24 EKX31461.1 - 4.6e-08 33.3 0.0 0.0063 16.8 0.1 3.0 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX31461.1 - 0.00013 22.2 0.1 0.029 14.7 0.1 3.2 2 0 0 2 2 2 1 PDZ domain Zip PF02535.22 EKX31462.1 - 6e-28 98.0 15.9 5.7e-27 94.8 15.9 2.2 1 1 0 1 1 1 1 ZIP Zinc transporter TAT_signal PF10518.9 EKX31463.1 - 0.015 15.1 0.9 0.015 15.1 0.9 1.7 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence PsbP PF01789.16 EKX31463.1 - 0.074 13.2 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 PsbP Glyco_transf_10 PF00852.19 EKX31464.1 - 1.4e-35 122.6 0.0 2.3e-35 121.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 EKX31464.1 - 1.6e-05 25.3 0.0 3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Fucosyltransferase, N-terminal adh_short PF00106.25 EKX31465.1 - 1.7e-28 99.4 0.1 2.5e-25 89.1 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EKX31465.1 - 2.8e-16 59.8 0.0 8e-16 58.3 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX31465.1 - 4.6e-07 29.9 0.0 8e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 EKX31465.1 - 0.011 15.2 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HTH_23 PF13384.6 EKX31466.1 - 0.043 13.6 1.0 0.086 12.7 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain DUF4554 PF15091.6 EKX31467.1 - 0.0043 16.0 0.5 0.0053 15.7 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4554) DUF4554 PF15091.6 EKX31468.1 - 0.00061 18.8 0.5 0.00075 18.5 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4554) DUF1825 PF08855.10 EKX31469.1 - 8.3e-19 67.4 0.1 1.1e-18 67.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1825) Arm PF00514.23 EKX31471.1 - 0.0054 16.7 0.7 9.1 6.5 0.0 3.8 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat Dynein_C PF18199.1 EKX31472.1 - 4.9e-109 364.3 0.0 8.7e-109 363.4 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EKX31472.1 - 4e-73 245.2 0.2 2.7e-71 239.2 0.5 2.4 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 EKX31472.1 - 2e-54 183.8 0.0 4.5e-54 182.7 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EKX31472.1 - 6.1e-45 152.2 0.0 1.8e-43 147.4 0.0 2.8 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain SWIRM-assoc_1 PF16495.5 EKX31472.1 - 0.0055 16.6 0.4 0.015 15.3 0.4 1.7 1 0 0 1 1 1 1 SWIRM-associated region 1 Pepdidase_M14_N PF18027.1 EKX31473.1 - 8.6e-16 58.2 0.5 1.8e-15 57.2 0.5 1.5 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 EKX31473.1 - 8.9e-14 52.0 0.0 2.1e-13 50.7 0.0 1.5 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 EKX31473.1 - 0.0014 17.8 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Endonuclease_NS PF01223.23 EKX31473.1 - 0.017 15.0 0.1 0.036 13.9 0.1 1.5 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease Runt PF00853.19 EKX31473.1 - 0.063 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Runt domain AMPK1_CBM PF16561.5 EKX31474.1 - 6.8e-20 71.1 0.3 1.3e-19 70.2 0.3 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase BRE1 PF08647.11 EKX31474.1 - 0.0066 16.5 8.7 6.7 6.9 0.0 3.5 2 1 0 2 2 2 1 BRE1 E3 ubiquitin ligase CBM53 PF16760.5 EKX31474.1 - 0.028 15.0 0.1 0.053 14.1 0.1 1.5 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) CorA PF01544.18 EKX31474.1 - 0.06 12.7 0.6 0.087 12.1 0.6 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein COG6 PF06419.11 EKX31474.1 - 0.084 11.1 4.8 0.7 8.0 0.5 2.1 1 1 1 2 2 2 0 Conserved oligomeric complex COG6 AKNA PF12443.8 EKX31474.1 - 0.1 13.2 0.2 13 6.5 0.0 2.6 1 1 1 2 2 2 0 AT-hook-containing transcription factor FliD_N PF02465.18 EKX31474.1 - 0.12 13.1 7.4 0.11 13.2 1.2 2.5 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF1192 PF06698.11 EKX31474.1 - 0.16 12.0 2.1 0.63 10.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) EcKinase PF02958.20 EKX31474.1 - 0.19 11.0 1.3 0.57 9.4 0.2 2.0 2 0 0 2 2 2 0 Ecdysteroid kinase PriC PF07445.12 EKX31474.1 - 0.39 10.6 4.6 0.53 10.2 1.5 2.3 2 1 0 2 2 2 0 Primosomal replication protein priC Laminin_II PF06009.12 EKX31474.1 - 0.48 10.4 7.4 0.095 12.7 1.9 2.3 1 1 0 2 2 2 0 Laminin Domain II Mt_ATP-synt_D PF05873.12 EKX31474.1 - 0.58 10.0 3.0 8.4 6.2 0.2 2.9 1 1 2 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) Cep57_MT_bd PF06657.13 EKX31474.1 - 0.8 10.2 4.4 1.2 9.7 0.0 2.9 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 FAM184 PF15665.5 EKX31474.1 - 1.6 8.5 10.1 2.7 7.7 5.2 2.3 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B DUF724 PF05266.14 EKX31474.1 - 1.8 8.4 6.2 8.1 6.2 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF883 PF05957.13 EKX31474.1 - 2.8 8.6 6.3 15 6.2 0.3 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Fib_alpha PF08702.10 EKX31474.1 - 3.6 7.8 6.7 3.1 8.0 1.2 2.4 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Collagen PF01391.18 EKX31475.1 - 7.1e-13 48.1 59.1 8.5e-08 31.8 25.2 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) EP400_N PF15790.5 EKX31475.1 - 0.021 13.7 0.1 0.031 13.1 0.1 1.2 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal Thioredoxin_4 PF13462.6 EKX31475.1 - 0.054 13.7 0.0 0.087 13.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin TPR_2 PF07719.17 EKX31478.1 - 0.00013 21.8 4.2 4.4 7.7 0.1 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX31478.1 - 0.00038 21.0 19.7 8.4 7.5 0.0 8.9 6 2 2 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX31478.1 - 0.04 14.0 1.5 3.8 7.8 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EKX31478.1 - 0.081 12.8 0.2 25 4.9 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX31478.1 - 0.11 12.8 15.8 5.2 7.4 0.0 6.2 6 1 1 7 7 7 0 Tetratricopeptide repeat ART PF01129.18 EKX31479.1 - 3.4e-05 23.2 0.0 4.8e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase ADPrib_exo_Tox PF03496.14 EKX31479.1 - 0.00025 20.4 0.0 0.018 14.4 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosyltransferase exoenzyme ARL2_Bind_BART PF11527.8 EKX31480.1 - 1.5e-30 105.6 6.9 4.4e-30 104.2 6.9 1.8 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Radical_SAM PF04055.21 EKX31480.1 - 0.013 15.9 0.0 0.031 14.7 0.0 1.7 1 0 0 1 1 1 0 Radical SAM superfamily Pneumo_att_G PF05539.11 EKX31480.1 - 2.5 7.6 6.5 3.5 7.1 6.5 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DSPn PF14671.6 EKX31482.1 - 3.2e-26 92.5 0.0 5.1e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EKX31482.1 - 1.2e-05 25.1 0.0 5.6e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX31482.1 - 0.00031 20.4 0.0 0.00059 19.5 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX31482.1 - 0.063 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Rib_5-P_isom_A PF06026.14 EKX31482.1 - 0.068 12.8 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DSPn PF14671.6 EKX31483.1 - 5.5e-27 94.9 0.0 3.2e-26 92.5 0.0 1.9 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EKX31483.1 - 3.1e-13 49.7 0.0 5.7e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX31483.1 - 0.00094 18.8 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX31483.1 - 0.0049 17.0 0.0 0.009 16.1 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Cys_Met_Meta_PP PF01053.20 EKX31485.1 - 6.6e-112 373.8 0.0 7.4e-112 373.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EKX31485.1 - 4.9e-06 25.7 0.0 6.8e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EKX31485.1 - 1.2e-05 24.7 0.0 1.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II SelA PF03841.13 EKX31485.1 - 0.00014 21.0 0.0 0.055 12.5 0.0 2.3 2 0 0 2 2 2 2 L-seryl-tRNA selenium transferase Beta_elim_lyase PF01212.21 EKX31485.1 - 0.00017 21.0 0.3 0.00051 19.4 0.3 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 EKX31485.1 - 0.0057 15.2 0.0 0.019 13.5 0.0 1.8 2 0 0 2 2 2 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.17 EKX31485.1 - 0.016 14.5 0.9 0.52 9.6 0.1 2.5 3 0 0 3 3 3 0 DegT/DnrJ/EryC1/StrS aminotransferase family SIP1 PF04938.12 EKX31486.1 - 9.8e-38 130.0 0.0 1.2e-37 129.7 0.0 1.1 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) GDP_Man_Dehyd PF16363.5 EKX31487.1 - 1.3e-12 47.8 0.0 1.7e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EKX31487.1 - 0.0056 16.2 0.0 0.007 15.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase PF01370.21 EKX31488.1 - 1.1e-08 34.8 0.0 1.7e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EKX31488.1 - 6.6e-07 29.0 0.0 8.9e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EKX31488.1 - 0.00044 19.4 0.0 0.0006 18.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EKX31488.1 - 0.0034 16.9 0.0 0.0057 16.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EKX31488.1 - 0.0071 15.5 0.0 0.014 14.6 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Pyr_redox_2 PF07992.14 EKX31488.1 - 0.017 14.4 0.0 0.02 14.2 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_4 PF07993.12 EKX31488.1 - 0.048 12.8 0.0 0.074 12.2 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein RmlD_sub_bind PF04321.17 EKX31488.1 - 0.1 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 EKX31488.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family NADH_B2 PF14813.6 EKX31490.1 - 2.9e-07 30.2 1.7 4e-07 29.7 1.7 1.3 1 1 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 FAM176 PF14851.6 EKX31491.1 - 0.025 14.2 0.1 0.025 14.2 0.1 1.1 1 0 0 1 1 1 0 FAM176 family CagA PF03507.13 EKX31495.1 - 0.023 14.6 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 CagA exotoxin Intron_maturas2 PF01348.21 EKX31495.1 - 0.13 12.2 0.2 0.36 10.8 0.2 1.7 1 0 0 1 1 1 0 Type II intron maturase Pkinase PF00069.25 EKX31497.1 - 3e-36 125.1 0.0 1.6e-23 83.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EKX31497.1 - 4.6e-17 62.2 0.0 2.6e-13 49.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX31497.1 - 0.0037 16.1 0.0 0.0073 15.1 0.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX31497.1 - 0.0065 16.4 0.0 0.0095 15.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX31497.1 - 0.017 14.5 0.1 0.029 13.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EKX31497.1 - 0.049 13.3 0.1 0.37 10.4 0.0 2.3 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 EKX31497.1 - 0.11 12.0 0.1 0.48 10.0 0.1 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase Mpv17_PMP22 PF04117.12 EKX31500.1 - 4.6e-17 62.0 1.8 4.6e-17 62.0 1.8 1.9 2 0 0 2 2 2 1 Mpv17 / PMP22 family Aa_trans PF01490.18 EKX31500.1 - 0.094 11.4 3.1 0.19 10.4 0.1 2.4 2 1 0 3 3 3 0 Transmembrane amino acid transporter protein CLIP1_ZNF PF16641.5 EKX31501.1 - 0.091 12.7 2.3 0.14 12.1 2.3 1.3 1 0 0 1 1 1 0 CLIP1 zinc knuckle IQ PF00612.27 EKX31502.1 - 2.1e-16 58.1 6.0 0.004 16.8 0.1 4.7 4 0 0 4 4 4 4 IQ calmodulin-binding motif AKAP28 PF14469.6 EKX31502.1 - 0.04 13.7 0.1 0.15 11.8 0.1 1.9 1 1 1 2 2 2 0 28 kDa A-kinase anchor Exo_endo_phos PF03372.23 EKX31505.1 - 2.3e-11 43.7 0.0 3.8e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family START PF01852.19 EKX31505.1 - 0.31 10.4 3.2 0.6 9.5 0.7 2.5 2 1 0 2 2 2 0 START domain tRNA_SAD PF07973.14 EKX31506.1 - 3.7e-14 52.5 0.0 1.1e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 EKX31506.1 - 1.9e-11 44.5 7.1 1.9e-11 44.5 7.1 1.8 2 1 0 2 2 2 1 DHHA1 domain HAMP PF00672.25 EKX31506.1 - 0.0087 16.4 0.6 0.024 15.0 0.4 2.0 2 0 0 2 2 2 1 HAMP domain Guanylate_cyc PF00211.20 EKX31507.1 - 1.8e-49 167.9 0.0 2e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 EKX31508.1 - 1.3e-55 188.5 0.0 1.7e-55 188.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX31508.1 - 2.2e-48 164.9 0.0 2.7e-48 164.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EKX31508.1 - 4.6e-06 26.7 0.1 0.027 14.4 0.0 3.1 2 1 1 3 3 3 3 Phosphotransferase enzyme family Kdo PF06293.14 EKX31508.1 - 0.0003 20.2 0.1 0.00046 19.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EKX31508.1 - 0.12 11.1 0.0 0.28 9.9 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase PDZ_2 PF13180.6 EKX31509.1 - 1.7e-05 25.1 0.1 5.8e-05 23.3 0.1 1.8 1 1 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX31509.1 - 2.1e-05 24.8 0.3 3.5e-05 24.1 0.3 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX31509.1 - 0.0045 16.8 0.5 0.023 14.6 0.5 2.1 1 1 0 1 1 1 1 PDZ domain Nab2p_Zf1 PF18260.1 EKX31509.1 - 2.9 7.9 5.5 1.2 9.2 0.3 2.4 2 0 0 2 2 2 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 Evr1_Alr PF04777.13 EKX31510.1 - 5.9e-08 33.1 0.2 6.4e-08 33.0 0.2 1.0 1 0 0 1 1 1 1 Erv1 / Alr family LisH_2 PF16045.5 EKX31510.1 - 0.054 12.5 0.1 0.075 12.1 0.1 1.2 1 0 0 1 1 1 0 LisH RVT_1 PF00078.27 EKX31512.1 - 1.8e-08 34.2 0.1 3.5e-08 33.3 0.1 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dynein_light PF01221.18 EKX31513.1 - 3.6e-06 27.2 3.0 2.4e-05 24.6 3.0 2.4 1 1 0 1 1 1 1 Dynein light chain type 1 Cytomega_UL84 PF06284.11 EKX31513.1 - 0.003 16.1 1.7 0.003 16.1 1.7 1.5 2 0 0 2 2 2 1 Cytomegalovirus UL84 protein Eapp_C PF10238.9 EKX31513.1 - 0.023 14.8 1.6 0.023 14.8 1.6 2.6 2 1 0 2 2 2 0 E2F-associated phosphoprotein NPR3 PF03666.13 EKX31513.1 - 0.1 11.4 14.5 0.11 11.2 0.6 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 SpoIIP PF07454.11 EKX31513.1 - 0.59 9.5 11.6 0.044 13.3 4.3 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Peptidase_U57 PF05582.12 EKX31513.1 - 2 7.6 7.7 0.21 10.8 1.9 2.0 2 0 0 2 2 2 0 YabG peptidase U57 RR_TM4-6 PF06459.12 EKX31513.1 - 2.5 7.9 20.3 0.089 12.6 8.3 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 EKX31513.1 - 5.3 5.2 23.4 0.045 12.0 7.8 2.1 2 0 0 2 2 2 0 CDC45-like protein Zip PF02535.22 EKX31513.1 - 7.9 5.6 6.4 0.68 9.1 0.8 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter TctB PF07331.11 EKX31514.1 - 1.3 9.3 11.8 1.7 8.9 11.8 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Polysacc_synt_C PF14667.6 EKX31514.1 - 9.3 6.3 13.8 46 4.0 12.0 2.1 1 1 1 2 2 2 0 Polysaccharide biosynthesis C-terminal domain TBCC PF07986.12 EKX31515.1 - 0.051 13.3 6.6 0.075 12.8 2.9 2.0 1 1 1 2 2 2 0 Tubulin binding cofactor C CAP_C PF08603.11 EKX31515.1 - 0.076 12.6 2.8 0.11 12.1 2.0 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) C terminal NOA36 PF06524.12 EKX31517.1 - 0.55 9.5 9.5 0.018 14.4 3.5 1.6 2 0 0 2 2 2 0 NOA36 protein DEAD PF00270.29 EKX31518.1 - 3.1e-26 92.2 0.0 8.7e-18 64.7 0.2 2.3 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX31518.1 - 1.2e-21 77.1 0.0 2.6e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX31518.1 - 8.9e-06 25.8 0.0 2e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EKX31518.1 - 0.015 15.6 1.9 1.2 9.4 1.9 2.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EKX31518.1 - 0.033 13.9 0.1 0.075 12.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EKX31518.1 - 0.47 10.8 2.7 20 5.5 2.6 2.4 1 1 0 1 1 1 0 AAA domain cNMP_binding PF00027.29 EKX31520.1 - 0.04 14.0 0.0 0.091 12.8 0.0 1.6 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain PGA2 PF07543.12 EKX31520.1 - 0.092 12.7 3.4 0.14 12.1 3.4 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 XFP_N PF09364.10 EKX31521.1 - 0.16 10.7 0.1 0.34 9.7 0.1 1.4 1 0 0 1 1 1 0 XFP N-terminal domain BEX PF04538.12 EKX31521.1 - 0.59 10.7 7.6 0.081 13.5 1.5 2.2 2 0 0 2 2 2 0 Brain expressed X-linked like family RWP-RK PF02042.15 EKX31522.1 - 3.2e-06 27.0 0.5 5.4e-06 26.3 0.5 1.3 1 0 0 1 1 1 1 RWP-RK domain HisKA PF00512.25 EKX31527.1 - 0.17 12.0 1.8 0.72 9.9 0.9 2.2 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Serine_rich PF08824.10 EKX31527.1 - 0.2 11.6 3.8 0.1 12.6 1.3 1.8 2 0 0 2 2 2 0 Serine rich protein interaction domain Ank_5 PF13857.6 EKX31528.1 - 1.2e-10 41.4 0.0 1.5e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX31528.1 - 1.4e-08 34.8 0.1 1.8e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 EKX31528.1 - 2.1e-07 31.4 0.1 2.2e-07 31.4 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX31528.1 - 4.3e-07 30.4 0.0 1.7e-06 28.5 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX31528.1 - 9.6e-07 28.7 0.0 1.6e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeat PDZ_6 PF17820.1 EKX31529.1 - 2.9e-12 46.3 0.2 1.1e-11 44.4 0.2 2.1 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX31529.1 - 4.4e-07 30.1 0.0 1.2e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX31529.1 - 1.8e-05 24.9 0.0 4.3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain RasGAP PF00616.19 EKX31529.1 - 3.7e-05 23.5 0.1 0.00014 21.6 0.1 1.9 1 1 1 2 2 2 1 GTPase-activator protein for Ras-like GTPase Tricorn_PDZ PF14685.6 EKX31529.1 - 0.018 15.0 0.1 0.044 13.8 0.1 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain GRASP55_65 PF04495.14 EKX31529.1 - 0.17 12.2 0.0 0.44 10.9 0.0 1.6 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Atg14 PF10186.9 EKX31529.1 - 0.51 9.4 9.8 0.83 8.7 9.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1690 PF07956.11 EKX31529.1 - 1 9.8 8.3 2.3 8.7 8.3 1.5 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF4200 PF13863.6 EKX31529.1 - 2.2 8.7 11.8 5 7.5 11.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Amino_oxidase PF01593.24 EKX31530.1 - 0.018 14.3 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Glyco_hydro_47 PF01532.20 EKX31531.1 - 0.014 14.4 0.0 0.014 14.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 47 Methyltransf_21 PF05050.12 EKX31532.1 - 5.2e-20 72.2 0.0 6.3e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase FkbM domain Biotin_lipoyl PF00364.22 EKX31533.1 - 5.1e-06 26.2 0.0 9.4e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Kre28 PF17097.5 EKX31533.1 - 0.021 13.8 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Spindle pole body component Scm3 PF10384.9 EKX31534.1 - 0.0051 16.5 2.4 3.2 7.6 0.0 2.7 2 0 0 2 2 2 2 Centromere protein Scm3 Fis1_TPR_C PF14853.6 EKX31534.1 - 0.01 15.9 0.1 0.031 14.3 0.1 1.8 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Sulfotransfer_2 PF03567.14 EKX31535.1 - 0.0081 16.1 0.4 0.28 11.0 0.4 2.3 1 1 0 1 1 1 1 Sulfotransferase family AgrD PF05931.11 EKX31535.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 Staphylococcal AgrD protein WD40 PF00400.32 EKX31536.1 - 2.2e-47 158.0 26.4 3.7e-08 33.9 1.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX31536.1 - 1.3e-11 44.6 0.6 0.03 14.6 0.0 4.6 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EKX31536.1 - 0.00065 18.5 8.0 0.14 10.7 0.1 5.0 2 1 2 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EKX31536.1 - 0.0013 17.8 1.0 3 6.7 0.1 4.0 2 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EKX31536.1 - 0.0076 14.8 0.1 0.2 10.2 0.1 2.3 2 1 1 3 3 3 1 Cytochrome D1 heme domain WD40_like PF17005.5 EKX31536.1 - 0.014 14.7 0.0 3.5 6.9 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain PQQ_3 PF13570.6 EKX31536.1 - 0.057 13.9 1.0 8.2 7.1 0.0 3.6 3 1 0 3 3 3 0 PQQ-like domain Cupin_8 PF13621.6 EKX31537.1 - 3.9e-12 46.4 0.0 1.5e-07 31.4 0.0 2.2 2 0 0 2 2 2 2 Cupin-like domain Cupin_4 PF08007.12 EKX31537.1 - 0.073 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein ABC_tran PF00005.27 EKX31538.1 - 0.0062 17.1 0.0 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EKX31538.1 - 0.0091 15.8 0.2 0.011 15.6 0.2 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Barstar PF01337.18 EKX31538.1 - 0.11 12.6 0.1 0.13 12.3 0.1 1.4 1 1 0 1 1 1 0 Barstar (barnase inhibitor) PhetRS_B1 PF18262.1 EKX31538.1 - 0.15 12.3 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain PP2C PF00481.21 EKX31539.1 - 7.2e-40 137.2 0.0 9e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PCI PF01399.27 EKX31540.1 - 5.3e-09 36.5 0.0 1.3e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 PCI domain Hint PF01079.20 EKX31541.1 - 2.5e-17 63.1 0.0 4.7e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Hint module DNA_ligase_OB PF03120.16 EKX31541.1 - 0.13 12.2 0.0 0.83 9.6 0.0 2.1 2 0 0 2 2 2 0 NAD-dependent DNA ligase OB-fold domain Pkinase_Tyr PF07714.17 EKX31542.1 - 1.1e-13 51.1 0.0 1.2e-13 51.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX31542.1 - 1.1e-07 31.5 0.0 1.2e-07 31.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain DUF309 PF03745.14 EKX31542.1 - 0.013 15.2 0.1 3.3 7.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF309) HNH_3 PF13392.6 EKX31542.1 - 0.048 13.4 0.5 5.9 6.7 0.0 2.1 2 0 0 2 2 2 0 HNH endonuclease Pkinase_Tyr PF07714.17 EKX31543.1 - 2.2e-34 119.0 0.0 2.5e-34 118.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX31543.1 - 1.5e-31 109.7 0.0 1.6e-31 109.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EKX31543.1 - 0.0068 16.4 0.0 0.0078 16.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX31543.1 - 0.0085 15.5 0.1 0.014 14.8 0.1 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EKX31543.1 - 0.015 14.3 0.1 0.019 14.0 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 EKX31543.1 - 0.087 12.1 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Mpp10 PF04006.12 EKX31544.1 - 0.19 10.1 28.5 0.2 10.1 28.5 1.0 1 0 0 1 1 1 0 Mpp10 protein DNA_pol_phi PF04931.13 EKX31544.1 - 0.26 9.3 41.2 0.27 9.3 41.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi CobT PF06213.12 EKX31544.1 - 0.34 10.2 28.8 0.35 10.2 28.8 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TRAP_alpha PF03896.16 EKX31544.1 - 0.35 10.0 20.5 0.4 9.8 20.5 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.12 EKX31544.1 - 0.45 8.7 32.6 0.45 8.7 32.6 1.0 1 0 0 1 1 1 0 Nop14-like family CTU2 PF10288.9 EKX31544.1 - 0.57 10.4 6.4 0.71 10.1 6.4 1.0 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Connexin PF00029.19 EKX31544.1 - 0.9 9.3 7.2 0.92 9.2 7.2 1.0 1 0 0 1 1 1 0 Connexin TFB6 PF17110.5 EKX31544.1 - 1.4 8.6 17.2 1.6 8.5 17.2 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH CPSF100_C PF13299.6 EKX31544.1 - 1.6 8.9 11.4 1.7 8.8 11.4 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SpoIIP PF07454.11 EKX31544.1 - 1.8 8.0 14.7 1.9 7.9 14.7 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CDC45 PF02724.14 EKX31544.1 - 2.4 6.3 26.5 2.5 6.3 26.5 1.0 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 EKX31544.1 - 2.5 8.5 12.4 2.9 8.3 12.4 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 ORC_WH_C PF18137.1 EKX31544.1 - 2.5 8.1 13.4 2.7 8.1 13.4 1.1 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal RR_TM4-6 PF06459.12 EKX31544.1 - 2.8 7.7 16.1 2.8 7.7 16.1 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 IFT57 PF10498.9 EKX31544.1 - 2.8 6.8 22.6 3 6.7 22.6 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 AIF_C PF14721.6 EKX31544.1 - 3.6 7.9 7.9 3.6 8.0 7.9 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Afi1 PF07792.12 EKX31544.1 - 4 7.9 16.5 4.4 7.8 16.5 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF913 PF06025.12 EKX31544.1 - 4.3 6.2 12.0 4.2 6.2 12.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DDHD PF02862.17 EKX31544.1 - 4.8 7.3 5.5 4.7 7.3 5.5 1.0 1 0 0 1 1 1 0 DDHD domain BUD22 PF09073.10 EKX31544.1 - 4.8 6.4 27.8 4.9 6.4 27.8 1.0 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 EKX31544.1 - 5 5.8 10.3 5 5.8 10.3 1.0 1 0 0 1 1 1 0 Presenilin GNAT_acetyltr_2 PF13718.6 EKX31544.1 - 6.3 6.1 7.1 7.2 5.9 7.1 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 EIIBC-GUT_N PF03612.14 EKX31544.1 - 6.3 6.5 7.1 7 6.3 7.1 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2722 PF10846.8 EKX31544.1 - 6.4 5.6 15.9 6.7 5.5 15.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) FYDLN_acid PF09538.10 EKX31544.1 - 6.6 7.5 27.8 7.6 7.3 27.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) U79_P34 PF03064.16 EKX31544.1 - 7 5.9 14.4 7.2 5.9 14.4 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RPN2_C PF18004.1 EKX31544.1 - 7 6.5 19.3 8.2 6.3 19.3 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF5523 PF17661.1 EKX31544.1 - 8.5 6.0 27.2 9.2 5.9 27.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF4820 PF16091.5 EKX31544.1 - 8.6 5.7 13.8 9.7 5.5 13.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RRM_1 PF00076.22 EKX31545.1 - 2e-10 40.3 0.0 3.7e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) XPC-binding PF09280.11 EKX31545.1 - 0.093 12.5 6.5 0.064 13.0 1.6 2.4 2 0 0 2 2 2 0 XPC-binding domain Glyco_hydro_92 PF07971.12 EKX31545.1 - 0.22 10.4 0.3 0.34 9.8 0.0 1.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 92 Pkinase_Tyr PF07714.17 EKX31547.1 - 2.4e-38 131.9 0.0 2.6e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX31547.1 - 4.2e-15 55.8 0.0 4.7e-15 55.7 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 EKX31548.1 - 4e-33 113.8 0.0 4.4e-08 33.6 0.0 4.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX31548.1 - 1.3e-23 83.0 0.0 1.4e-05 25.5 0.0 4.7 3 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX31548.1 - 5.2e-20 71.2 1.0 0.00051 20.3 0.0 6.5 3 3 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX31548.1 - 5.8e-17 60.1 0.0 0.076 13.6 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 EKX31548.1 - 2e-08 34.3 0.1 15 6.3 0.0 6.2 7 0 0 7 7 7 2 Ankyrin repeat Ins_beta PF03488.14 EKX31548.1 - 0.002 18.1 10.8 29 4.8 0.1 5.7 6 0 0 6 6 6 0 Nematode insulin-related peptide beta type ShK PF01549.24 EKX31548.1 - 0.033 14.7 6.3 50 4.6 0.0 5.1 5 0 0 5 5 5 0 ShK domain-like DUF5642 PF18702.1 EKX31548.1 - 0.069 12.9 4.2 3.1 7.5 0.3 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF5642) XAF1_C PF18608.1 EKX31548.1 - 7.6 6.2 8.1 75 3.0 0.1 3.9 4 0 0 4 4 4 0 XIAP-associated factor 1 C-terminal domain Pkinase_Tyr PF07714.17 EKX31549.1 - 3.7e-38 131.3 0.0 4.1e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX31549.1 - 1.1e-14 54.5 0.0 1.2e-14 54.3 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain U-box PF04564.15 EKX31550.1 - 1.9e-19 69.6 0.0 2.2e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX31550.1 - 1.5e-05 24.7 0.0 2.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EKX31550.1 - 0.00018 21.4 0.1 0.00029 20.8 0.1 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-NOSIP PF15906.5 EKX31550.1 - 0.0058 16.7 0.0 0.0072 16.4 0.0 1.1 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Pkinase_Tyr PF07714.17 EKX31551.1 - 4.2e-47 160.6 0.0 4.9e-47 160.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX31551.1 - 2.3e-19 69.8 0.0 2.7e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 EKX31552.1 - 3.2e-10 40.4 4.1 0.00027 21.6 0.0 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF728 PF05304.12 EKX31552.1 - 0.047 13.5 0.1 0.05 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF728) Glucodextran_B PF09136.10 EKX31552.1 - 0.13 12.7 1.1 12 6.3 0.1 2.1 2 0 0 2 2 2 0 Glucodextranase, domain B Asp_protease_2 PF13650.6 EKX31553.1 - 3.6e-05 24.3 0.0 8.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EKX31553.1 - 6.3e-05 23.5 0.0 0.00023 21.7 0.0 1.9 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 EKX31553.1 - 0.0002 21.3 3.6 0.00039 20.4 3.6 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.17 EKX31553.1 - 0.0002 21.6 0.0 0.00045 20.5 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 EKX31553.1 - 0.00033 20.4 2.5 0.00061 19.5 2.5 1.4 1 0 0 1 1 1 1 Zinc knuckle RVP PF00077.20 EKX31553.1 - 0.094 13.0 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_4 PF14392.6 EKX31553.1 - 0.33 10.7 1.9 0.61 9.9 1.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Ephrin_rec_like PF07699.13 EKX31555.1 - 7.8e-248 800.3 908.1 1.2e-12 47.3 6.3 80.8 64 16 23 87 87 87 75 Putative ephrin-receptor like EGF_CA PF07645.15 EKX31555.1 - 5.6e-20 71.3 50.6 4.8e-09 36.3 2.7 58.5 61 11 9 70 70 70 6 Calcium-binding EGF domain EGF_3 PF12947.7 EKX31555.1 - 1.7e-10 40.9 39.0 1.1e-08 35.1 7.5 44.6 51 2 1 52 52 52 5 EGF domain cEGF PF12662.7 EKX31555.1 - 5.2e-07 29.5 9.7 5.6e-05 23.0 0.7 67.5 68 11 5 73 73 73 10 Complement Clr-like EGF-like EGF PF00008.27 EKX31555.1 - 3.9e-06 27.1 15.4 3e-05 24.2 2.8 48.1 57 1 2 59 59 59 8 EGF-like domain EGF_MSP1_1 PF12946.7 EKX31555.1 - 0.00042 20.3 3.4 0.00042 20.3 3.4 43.4 46 1 2 48 48 48 10 MSP1 EGF domain 1 hEGF PF12661.7 EKX31555.1 - 0.0038 17.8 2.2 0.0038 17.8 2.2 52.5 58 0 0 58 58 58 10 Human growth factor-like EGF DUF3086 PF11285.8 EKX31556.1 - 0.01 15.0 0.0 0.021 13.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3086) PAXX PF15384.6 EKX31556.1 - 0.05 13.3 0.1 0.071 12.8 0.1 1.2 1 0 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 DUF1295 PF06966.12 EKX31556.1 - 0.069 12.7 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) DUF1682 PF07946.14 EKX31558.1 - 1e-47 163.0 0.0 1e-47 163.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1682) CDC45 PF02724.14 EKX31558.1 - 0.077 11.3 3.2 0.065 11.5 1.9 1.4 2 0 0 2 2 2 0 CDC45-like protein ORC6 PF05460.13 EKX31558.1 - 0.084 12.1 0.5 0.14 11.4 0.5 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Cys_rich_FGFR PF00839.17 EKX31559.1 - 0.008 16.3 0.4 2.5 8.3 0.3 2.7 2 1 0 2 2 2 2 Cysteine rich repeat Med24_N PF11277.8 EKX31559.1 - 0.02 13.0 0.0 0.032 12.3 0.0 1.2 1 1 0 1 1 1 0 Mediator complex subunit 24 N-terminal Cyt-b5 PF00173.28 EKX31560.1 - 6e-25 87.2 0.1 7.9e-25 86.8 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Rdx PF10262.9 EKX31561.1 - 0.00079 19.6 0.1 0.0017 18.5 0.1 1.7 1 1 0 1 1 1 1 Rdx family Antimicrobial17 PF08129.11 EKX31561.1 - 0.056 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta enterocin family DHHC PF01529.20 EKX31562.1 - 7e-32 110.3 9.9 8e-32 110.2 9.9 1.0 1 0 0 1 1 1 1 DHHC palmitoyltransferase MTHFR_C PF12225.8 EKX31562.1 - 0.44 10.2 9.9 0.4 10.4 8.4 1.7 2 0 0 2 2 2 0 Methylene-tetrahydrofolate reductase C terminal Spt4 PF06093.13 EKX31562.1 - 1.3 9.2 7.0 2 8.6 7.0 1.3 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger Methyltransf_16 PF10294.9 EKX31563.1 - 2.4e-23 82.7 0.0 1.6e-22 80.1 0.0 1.9 1 1 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EKX31563.1 - 1.2e-05 24.9 0.0 2.9e-05 23.7 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.19 EKX31563.1 - 0.0045 16.8 0.0 0.0081 15.9 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Sulfotransfer_3 PF13469.6 EKX31564.1 - 0.047 14.1 0.2 0.8 10.0 0.0 2.4 3 0 0 3 3 3 0 Sulfotransferase family PAS_9 PF13426.7 EKX31565.1 - 0.16 12.2 0.0 0.4 11.0 0.0 1.7 1 0 0 1 1 1 0 PAS domain LysM PF01476.20 EKX31566.1 - 1e-06 28.7 0.0 2.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 LysM domain TIG PF01833.24 EKX31566.1 - 0.0098 15.9 0.4 0.23 11.5 0.2 2.5 2 0 0 2 2 2 1 IPT/TIG domain Njmu-R1 PF15053.6 EKX31566.1 - 0.19 10.8 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 Mjmu-R1-like protein family adh_short PF00106.25 EKX31567.1 - 2.9e-18 66.0 0.0 8.1e-15 54.8 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EKX31567.1 - 2.7e-13 50.0 0.0 8.6e-06 25.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX31567.1 - 3e-10 40.3 0.1 5.4e-10 39.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EKX31567.1 - 0.00014 21.4 0.0 0.00035 20.1 0.1 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EKX31567.1 - 0.0011 19.2 0.1 0.002 18.4 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EKX31567.1 - 0.0027 17.6 0.4 0.0054 16.6 0.4 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EKX31567.1 - 0.0063 15.7 0.4 0.0089 15.2 0.4 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.19 EKX31567.1 - 0.023 14.0 0.1 0.039 13.3 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EKX31567.1 - 0.068 12.6 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Glycos_transf_2 PF00535.26 EKX31568.1 - 0.074 12.9 0.0 0.19 11.5 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 2 Sulf_transp PF04143.14 EKX31569.1 - 2.5e-37 129.1 24.1 3e-37 128.8 24.1 1.1 1 0 0 1 1 1 1 Sulphur transport Sulf_transp PF04143.14 EKX31570.1 - 2.2e-26 93.2 29.8 2e-14 53.9 10.6 2.9 1 1 2 3 3 3 2 Sulphur transport DHC_N2 PF08393.13 EKX31572.1 - 4e-11 42.6 0.1 4.3e-11 42.6 0.1 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 HsbA PF12296.8 EKX31572.1 - 0.022 15.2 0.0 0.023 15.1 0.0 1.0 1 0 0 1 1 1 0 Hydrophobic surface binding protein A Sulf_transp PF04143.14 EKX31573.1 - 4e-38 131.7 21.6 4.9e-38 131.4 21.6 1.1 1 0 0 1 1 1 1 Sulphur transport Pkinase PF00069.25 EKX31574.1 - 0.0086 15.5 0.0 0.0086 15.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain FlxA PF14282.6 EKX31575.1 - 0.00024 21.0 0.4 0.00045 20.2 0.4 1.4 1 0 0 1 1 1 1 FlxA-like protein TSC22 PF01166.18 EKX31575.1 - 0.018 15.4 0.8 0.056 13.8 0.8 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family zf-C2H2_8 PF15909.5 EKX31575.1 - 0.021 15.1 0.0 0.11 12.8 0.0 2.2 2 0 0 2 2 2 0 C2H2-type zinc ribbon MscS_porin PF12795.7 EKX31575.1 - 0.052 13.1 0.5 0.08 12.5 0.5 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain ZapB PF06005.12 EKX31575.1 - 0.057 13.9 0.6 0.13 12.7 0.6 1.6 1 0 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 EKX31575.1 - 0.079 12.7 1.9 0.23 11.3 1.9 1.7 1 0 0 1 1 1 0 Septum formation initiator TcpS PF17456.2 EKX31575.1 - 0.086 12.9 0.4 0.21 11.6 0.4 1.6 1 0 0 1 1 1 0 Toxin-coregulated pilus protein S DUF5082 PF16888.5 EKX31575.1 - 0.24 11.7 1.5 0.49 10.7 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) bZIP_2 PF07716.15 EKX31575.1 - 1.3 9.1 3.4 3 8.0 3.4 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Rap1_C PF11626.8 EKX31577.1 - 0.062 13.4 0.1 0.36 10.9 0.0 2.4 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain TehB PF03848.14 EKX31577.1 - 0.1 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB AATF-Che1 PF13339.6 EKX31577.1 - 0.17 12.5 0.8 32 5.2 0.3 2.6 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor Caud_tail_N PF16838.5 EKX31578.1 - 0.076 13.4 0.6 0.14 12.6 0.6 1.4 1 0 0 1 1 1 0 Caudoviral major tail protein N-terminus Methyltransf_2 PF00891.18 EKX31578.1 - 0.18 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain LRRNT PF01462.18 EKX31578.1 - 1.4 8.6 6.1 3.1 7.5 6.1 1.6 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Bromo_TP PF07524.13 EKX31580.1 - 1.6e-16 60.1 0.3 2.7e-16 59.3 0.3 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.9 EKX31580.1 - 3.5e-12 46.7 1.1 3.5e-12 46.7 1.1 2.6 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term TFIID-31kDa PF02291.15 EKX31580.1 - 0.038 14.0 1.2 0.17 11.9 0.1 2.3 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP_like PF17027.5 EKX31580.1 - 0.07 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Histone-fold protein Tnp_22_trimer PF17489.2 EKX31580.1 - 0.84 9.7 4.3 4.4 7.4 0.3 2.4 2 0 0 2 2 2 0 L1 transposable element trimerization domain Myb_DNA-binding PF00249.31 EKX31582.1 - 5.4e-19 68.1 2.9 7.7e-11 42.0 0.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX31582.1 - 1.3e-13 51.0 0.9 3.1e-06 27.3 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain MCRS_N PF13325.6 EKX31582.1 - 0.00028 21.0 0.0 0.083 12.9 0.0 2.5 2 0 0 2 2 2 2 N-terminal region of micro-spherule protein Myb_DNA-bind_7 PF15963.5 EKX31582.1 - 0.0004 20.2 0.3 0.029 14.2 0.1 3.2 2 0 0 2 2 2 1 Myb DNA-binding like I-set PF07679.16 EKX31582.1 - 0.011 15.8 0.0 0.03 14.4 0.0 1.7 1 0 0 1 1 1 0 Immunoglobulin I-set domain SANT_DAMP1_like PF16282.5 EKX31582.1 - 0.049 13.8 0.1 6.3 7.1 0.0 2.3 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_5 PF13873.6 EKX31582.1 - 0.71 10.0 11.8 1.1 9.4 0.1 4.8 4 1 1 5 5 5 0 Myb/SANT-like DNA-binding domain LRR_4 PF12799.7 EKX31583.1 - 5.7e-16 58.4 12.2 3.6e-05 24.0 0.0 4.1 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX31583.1 - 2e-15 56.3 8.6 0.00013 21.6 1.6 3.6 3 1 0 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 EKX31583.1 - 0.00011 21.8 3.1 0.1 12.1 1.5 2.6 2 1 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 EKX31583.1 - 0.00014 21.9 10.1 5.4 8.0 0.1 7.0 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.6 EKX31583.1 - 0.023 14.7 5.4 16 5.9 0.1 5.1 5 0 0 5 5 5 0 Leucine Rich repeat COPI_C PF06957.11 EKX31583.1 - 0.2 10.4 11.5 0.035 12.9 8.1 1.4 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus CDC45 PF02724.14 EKX31583.1 - 0.69 8.1 15.8 0.9 7.8 15.8 1.2 1 0 0 1 1 1 0 CDC45-like protein HSP90 PF00183.18 EKX31583.1 - 1.3 7.8 15.3 1.9 7.3 15.3 1.3 1 0 0 1 1 1 0 Hsp90 protein GREB1 PF15782.5 EKX31583.1 - 1.8 5.6 10.2 2.1 5.3 10.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TMEM119 PF15724.5 EKX31583.1 - 2.8 7.9 14.6 5.6 7.0 14.6 1.5 1 0 0 1 1 1 0 TMEM119 family LAP1C PF05609.12 EKX31583.1 - 3.3 6.7 15.8 4.3 6.3 15.8 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) dsRBD2 PF17842.1 EKX31583.1 - 3.4 7.9 7.0 6.1 7.0 7.0 1.4 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 TP53IP5 PF15331.6 EKX31583.1 - 4.1 7.5 14.0 9.8 6.3 14.0 1.6 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 ALMT PF11744.8 EKX31583.1 - 9.9 4.9 13.0 14 4.3 13.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Cortex-I_coil PF09304.10 EKX31584.1 - 0.013 15.7 7.1 0.025 14.8 7.1 1.6 1 1 0 1 1 1 0 Cortexillin I, coiled coil Cluap1 PF10234.9 EKX31584.1 - 0.057 12.8 7.6 0.066 12.6 7.6 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 APG6_N PF17675.1 EKX31584.1 - 3 8.4 11.3 5.5 7.5 11.0 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region MatE PF01554.18 EKX31585.1 - 5.1e-12 45.7 26.2 2.4e-09 37.1 3.9 2.4 2 0 0 2 2 2 2 MatE TPR_19 PF14559.6 EKX31586.1 - 0.00066 20.1 0.9 0.0019 18.7 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.6 EKX31586.1 - 0.025 14.9 0.3 0.86 10.0 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 EKX31586.1 - 0.13 12.6 0.1 0.54 10.8 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Sporozoite_P67 PF05642.11 EKX31586.1 - 0.78 7.8 2.4 1.2 7.2 2.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GT87 PF09594.10 EKX31587.1 - 0.021 14.6 0.1 0.035 13.8 0.1 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 87 ADH_zinc_N PF00107.26 EKX31588.1 - 1e-14 54.6 0.9 1.6e-14 54.0 0.9 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EKX31588.1 - 2.4e-08 33.8 1.4 1.5e-07 31.3 0.2 2.5 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EKX31588.1 - 3.8e-08 34.5 0.6 7.6e-08 33.5 0.3 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF4336 PF14234.6 EKX31589.1 - 1.3e-05 24.5 0.0 0.13 11.4 0.0 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) DUF1090 PF06476.12 EKX31591.1 - 0.0093 16.1 3.3 1.4 9.1 0.4 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1090) PSII_Pbs31 PF18240.1 EKX31591.1 - 0.046 14.1 0.3 0.56 10.7 0.1 2.1 1 1 1 2 2 2 0 Photosystem II Psb31 protein HMG_box_2 PF09011.10 EKX31591.1 - 0.089 13.4 0.4 1.7 9.3 0.1 2.1 2 0 0 2 2 2 0 HMG-box domain Scm3 PF10384.9 EKX31591.1 - 0.12 12.2 1.4 21 4.9 0.0 2.9 3 0 0 3 3 3 0 Centromere protein Scm3 DUF806 PF05657.11 EKX31591.1 - 0.19 12.2 0.5 11 6.5 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF806) Ank_2 PF12796.7 EKX31593.1 - 8e-30 103.3 1.2 3.1e-07 30.9 0.0 4.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX31593.1 - 6.6e-26 90.3 0.0 1.9e-05 25.1 0.0 4.8 3 2 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX31593.1 - 2.4e-20 72.3 5.6 0.022 15.1 0.0 6.5 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX31593.1 - 5e-11 41.8 0.1 7.3 7.5 0.0 7.3 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 EKX31593.1 - 4.5e-09 36.3 3.1 1.3 9.6 0.0 6.5 7 0 0 7 7 7 2 Ankyrin repeat BDHCT PF08072.11 EKX31593.1 - 2.7 8.1 4.1 24 5.1 0.1 3.6 4 0 0 4 4 4 0 BDHCT (NUC031) domain Ank_2 PF12796.7 EKX31597.1 - 6.8e-49 164.4 0.0 5.3e-10 39.7 0.0 4.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX31597.1 - 1.3e-31 108.5 0.0 2.8e-06 27.7 0.0 5.8 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX31597.1 - 2.1e-24 85.2 0.1 0.14 12.6 0.0 8.1 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX31597.1 - 1.5e-19 68.0 0.0 0.15 12.7 0.0 7.5 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 EKX31597.1 - 1.4e-15 56.9 0.0 1.1 9.9 0.0 7.4 8 0 0 8 8 8 4 Ankyrin repeat Ins_beta PF03488.14 EKX31597.1 - 6.4e-07 29.3 17.3 5.8 7.0 0.1 7.1 7 0 0 7 7 7 3 Nematode insulin-related peptide beta type FBD PF08387.10 EKX31597.1 - 0.00099 18.9 0.0 12 5.8 0.0 5.5 8 0 0 8 8 8 1 FBD DUF899 PF05988.12 EKX31597.1 - 0.0011 18.6 0.0 1.4 8.4 0.0 3.1 1 1 1 3 3 3 2 Bacterial protein of unknown function (DUF899) Hva1_TUDOR PF11160.8 EKX31597.1 - 0.054 13.7 0.4 66 3.8 0.0 4.7 5 1 0 5 5 5 0 Hypervirulence associated proteins TUDOR domain Imm17 PF15562.6 EKX31597.1 - 0.13 12.1 0.0 52 3.8 0.0 4.2 6 0 0 6 6 6 0 Immunity protein 17 VHS PF00790.19 EKX31597.1 - 0.25 11.2 0.3 2.4e+02 1.5 0.0 4.4 5 0 0 5 5 5 0 VHS domain Pkinase_Tyr PF07714.17 EKX31598.1 - 1.2e-20 74.0 0.0 1.3e-20 73.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX31598.1 - 5.4e-06 26.0 0.1 6.3e-06 25.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain SNF2_N PF00176.23 EKX31599.1 - 9.8e-22 77.1 0.2 1e-21 77.1 0.2 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain Ank_4 PF13637.6 EKX31600.1 - 3.5e-18 65.7 0.1 8.5e-09 35.8 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX31600.1 - 1.5e-12 47.9 0.1 3.8e-12 46.6 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX31600.1 - 5e-09 36.3 0.4 0.012 15.9 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX31600.1 - 3.2e-08 33.2 0.0 0.2 12.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EKX31600.1 - 3.5e-05 24.1 0.1 1.1 9.8 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ins_beta PF03488.14 EKX31600.1 - 0.54 10.3 2.6 46 4.1 0.0 3.1 3 0 0 3 3 3 0 Nematode insulin-related peptide beta type REJ PF02010.15 EKX31601.1 - 1.2e-36 126.5 3.6 3.1e-35 121.9 3.0 3.0 2 1 1 3 3 3 2 REJ domain PKD PF00801.20 EKX31601.1 - 4.4e-06 26.5 3.7 1.7 8.5 0.0 5.0 4 0 0 4 4 4 3 PKD domain PDZ_6 PF17820.1 EKX31601.1 - 0.00097 18.9 0.1 0.0033 17.2 0.1 2.0 1 0 0 1 1 1 1 PDZ domain GPS PF01825.21 EKX31601.1 - 0.15 12.6 2.1 0.38 11.3 2.1 1.7 1 0 0 1 1 1 0 GPCR proteolysis site, GPS, motif F5_F8_type_C PF00754.25 EKX31602.1 - 0.00013 22.1 1.2 0.00049 20.2 0.0 2.2 2 0 0 2 2 2 1 F5/8 type C domain SAP PF02037.27 EKX31603.1 - 1.5e-09 37.4 0.4 7.5e-09 35.1 0.2 2.1 2 0 0 2 2 2 1 SAP domain SnoaL_3 PF13474.6 EKX31603.1 - 2.3e-05 24.6 0.1 3.5e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 EKX31603.1 - 0.0011 19.5 0.0 0.0029 18.2 0.1 1.7 2 0 0 2 2 2 1 SnoaL-like domain NTF2 PF02136.20 EKX31603.1 - 0.01 16.4 0.0 0.019 15.5 0.0 1.5 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain Ion_trans PF00520.31 EKX31604.1 - 0.00015 21.1 6.0 0.00016 21.0 6.0 1.1 1 0 0 1 1 1 1 Ion transport protein DUF2070 PF09843.9 EKX31604.1 - 0.57 8.4 6.3 0.65 8.2 6.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PDZ_2 PF13180.6 EKX31605.1 - 0.00035 20.9 0.1 0.00073 19.8 0.1 1.5 1 0 0 1 1 1 1 PDZ domain SHIPPO-rpt PF07004.12 EKX31605.1 - 0.00068 20.4 34.6 0.49 11.4 1.0 8.3 8 0 0 8 8 8 3 Sperm-tail PG-rich repeat PDZ PF00595.24 EKX31605.1 - 0.0018 18.6 0.2 0.049 14.0 0.0 2.5 1 1 1 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EKX31605.1 - 0.0042 16.9 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX31605.1 - 0.018 15.0 0.0 0.065 13.2 0.0 2.0 2 0 0 2 2 2 0 Tricorn protease PDZ domain TetR_C_6 PF13977.6 EKX31606.1 - 0.081 13.1 0.8 0.26 11.5 0.0 2.0 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal PhoR PF11808.8 EKX31606.1 - 0.12 12.8 0.2 3.2 8.2 0.0 2.5 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR Dynamin_N PF00350.23 EKX31607.1 - 3.9e-24 85.6 3.3 2.8e-12 47.0 0.1 2.8 2 1 1 3 3 3 2 Dynamin family MMR_HSR1 PF01926.23 EKX31607.1 - 1.1e-15 57.6 0.1 2.9e-15 56.3 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EKX31607.1 - 7.3e-10 38.7 0.4 5.2e-09 35.9 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SAM_2 PF07647.17 EKX31607.1 - 2.2e-08 34.1 0.1 4.4e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RsgA_GTPase PF03193.16 EKX31607.1 - 1.1e-07 31.9 0.2 0.022 14.7 0.0 2.7 1 1 1 2 2 2 2 RsgA GTPase SAM_1 PF00536.30 EKX31607.1 - 1.2e-07 32.0 0.1 2.6e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) FeoB_N PF02421.18 EKX31607.1 - 5.1e-06 26.1 0.8 0.095 12.2 0.0 2.8 3 0 0 3 3 3 2 Ferrous iron transport protein B IIGP PF05049.13 EKX31607.1 - 0.00075 18.7 2.5 0.0034 16.5 0.4 2.7 2 1 0 2 2 2 1 Interferon-inducible GTPase (IIGP) cobW PF02492.19 EKX31607.1 - 0.00093 18.8 0.1 0.029 14.0 0.0 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 EKX31607.1 - 0.002 18.4 0.0 0.01 16.1 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 EKX31607.1 - 0.0021 17.8 0.1 0.075 12.8 0.0 2.8 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AIG1 PF04548.16 EKX31607.1 - 0.011 15.1 6.6 0.013 14.8 2.1 3.0 3 1 0 3 3 3 0 AIG1 family ABC_tran PF00005.27 EKX31607.1 - 0.015 15.8 0.7 0.096 13.2 0.1 2.6 2 1 0 2 2 2 0 ABC transporter Ras PF00071.22 EKX31607.1 - 0.1 12.2 1.1 0.53 9.9 0.3 2.5 2 1 0 2 2 2 0 Ras family FlgO PF17680.1 EKX31607.1 - 0.12 12.1 0.3 0.25 11.1 0.3 1.5 1 0 0 1 1 1 0 FlgO protein Septin PF00735.18 EKX31607.1 - 0.12 11.6 0.1 0.12 11.6 0.1 2.0 3 0 0 3 3 3 0 Septin Apolipoprotein PF01442.18 EKX31607.1 - 0.22 11.4 12.1 0.34 10.8 0.7 3.0 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 EKX31607.1 - 0.36 10.9 2.9 1.5 8.8 2.1 2.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ras PF00071.22 EKX31612.1 - 1.8e-34 118.7 0.2 2.1e-34 118.5 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EKX31612.1 - 2.7e-26 92.1 0.2 3.8e-26 91.7 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EKX31612.1 - 6.6e-09 35.5 0.0 7.8e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EKX31612.1 - 3.4e-06 26.6 0.2 4e-06 26.4 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 EKX31612.1 - 1.5e-05 24.0 0.3 0.01 14.7 0.0 2.0 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) GTP_EFTU PF00009.27 EKX31612.1 - 0.0048 16.5 0.1 0.026 14.1 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 EKX31612.1 - 0.005 16.1 0.2 0.067 12.3 0.1 2.5 1 1 1 2 2 2 1 G-protein alpha subunit SRPRB PF09439.10 EKX31612.1 - 0.095 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ion_trans PF00520.31 EKX31613.1 - 0.0025 17.1 0.0 0.0027 17.0 0.0 1.0 1 0 0 1 1 1 1 Ion transport protein Ion_trans PF00520.31 EKX31614.1 - 3.5e-22 78.8 9.0 4.4e-22 78.5 9.0 1.1 1 0 0 1 1 1 1 Ion transport protein PH PF00169.29 EKX31614.1 - 3.6e-06 27.4 0.0 6.6e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 PH domain PKD_channel PF08016.12 EKX31614.1 - 0.044 12.4 6.9 0.65 8.6 1.4 2.3 1 1 1 2 2 2 0 Polycystin cation channel DUF4079 PF13301.6 EKX31614.1 - 1.3 9.2 4.1 5.8 7.1 0.1 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF4079) Ion_trans PF00520.31 EKX31615.1 - 2.8e-11 43.1 2.8 1.5e-05 24.4 0.6 2.2 2 0 0 2 2 2 2 Ion transport protein PH PF00169.29 EKX31615.1 - 7.1e-06 26.5 0.0 2e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 PH domain EF-hand_6 PF13405.6 EKX31615.1 - 0.0018 18.1 0.9 0.082 12.9 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 EKX31615.1 - 0.0094 15.4 0.4 0.55 9.9 0.0 3.0 2 0 0 2 2 2 1 EF hand PTRF_SDPR PF15237.6 EKX31615.1 - 0.025 14.2 2.3 3.1 7.4 0.1 2.4 2 0 0 2 2 2 0 PTRF/SDPR family THOC7 PF05615.13 EKX31615.1 - 0.025 14.8 0.4 0.025 14.8 0.4 2.5 4 0 0 4 4 4 0 Tho complex subunit 7 DUF5305 PF17231.2 EKX31615.1 - 0.069 12.5 0.4 0.19 11.1 0.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Laminin_II PF06009.12 EKX31615.1 - 0.11 12.6 0.6 0.32 11.0 0.1 2.1 2 0 0 2 2 2 0 Laminin Domain II GCN5L1 PF06320.13 EKX31615.1 - 0.16 12.1 1.4 9.5 6.4 0.0 3.0 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) LPD3 PF18798.1 EKX31616.1 - 0.01 16.1 3.5 0.025 14.8 0.3 2.2 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 3 DUF1949 PF09186.11 EKX31616.1 - 0.031 14.2 0.2 0.078 12.9 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1949) BUD22 PF09073.10 EKX31616.1 - 0.13 11.6 14.6 0.29 10.5 13.6 1.7 1 1 1 2 2 2 0 BUD22 IZUMO PF15005.6 EKX31616.1 - 0.32 11.5 12.2 1.8 9.0 3.2 2.5 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Nup54_57_C PF18570.1 EKX31616.1 - 0.74 9.4 7.2 1.8 8.2 0.0 3.9 4 0 0 4 4 4 0 NUP57/Nup54 C-terminal domain APC_N_CC PF16689.5 EKX31616.1 - 1 9.5 0.0 1 9.5 0.0 3.7 4 0 0 4 4 4 0 Coiled-coil N-terminus of APC, dimerisation domain LUC7 PF03194.15 EKX31616.1 - 4.3 6.9 16.5 7.7 6.1 4.3 2.2 1 1 1 2 2 2 0 LUC7 N_terminus DUF2205 PF10224.9 EKX31616.1 - 4.6 7.3 14.3 1.9 8.5 2.0 3.6 2 1 0 2 2 2 0 Short coiled-coil protein MORN PF02493.20 EKX31618.1 - 2.7e-13 49.0 12.0 1.3e-05 24.7 0.1 3.0 3 0 0 3 3 3 3 MORN repeat DUF3048_C PF17479.2 EKX31618.1 - 0.083 13.3 0.0 0.092 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3048) C-terminal domain PX PF00787.24 EKX31620.1 - 6.8e-09 35.7 0.1 9.3e-09 35.3 0.1 1.1 1 0 0 1 1 1 1 PX domain adh_short PF00106.25 EKX31621.1 - 1.7e-23 83.1 0.0 2.3e-19 69.6 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EKX31621.1 - 4.4e-13 49.3 0.0 9.8e-12 44.9 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX31621.1 - 0.00012 22.1 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EKX31621.1 - 0.00033 20.2 0.0 0.00051 19.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 EKX31621.1 - 0.046 13.0 0.0 0.072 12.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Baculo_PEP_C PF04513.12 EKX31622.1 - 2.5e-09 37.3 0.4 4.6e-09 36.4 0.4 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 EKX31622.1 - 5.2e-06 26.5 0.4 9.4e-06 25.7 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 EKX31622.1 - 4.5e-05 23.4 0.5 6.3e-05 22.9 0.5 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Fib_alpha PF08702.10 EKX31622.1 - 0.00014 22.1 0.3 0.00023 21.4 0.3 1.3 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family DUF2730 PF10805.8 EKX31622.1 - 0.00032 20.7 2.2 0.00076 19.5 2.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2730) DUF16 PF01519.16 EKX31622.1 - 0.00033 21.1 3.3 0.00073 20.0 3.3 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF16 Filament PF00038.21 EKX31622.1 - 0.00078 19.1 0.1 0.0011 18.6 0.1 1.2 1 0 0 1 1 1 1 Intermediate filament protein LPP PF04728.13 EKX31622.1 - 0.001 19.4 8.9 0.015 15.7 2.4 3.1 1 1 2 3 3 3 2 Lipoprotein leucine-zipper Spc7 PF08317.11 EKX31622.1 - 0.0012 17.8 1.1 0.0017 17.3 1.1 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF5082 PF16888.5 EKX31622.1 - 0.0017 18.7 1.1 0.0048 17.2 1.2 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF5082) COG5 PF10392.9 EKX31622.1 - 0.0026 17.9 0.2 0.0044 17.2 0.2 1.3 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Bacillus_HBL PF05791.11 EKX31622.1 - 0.0029 17.5 0.5 0.0047 16.8 0.5 1.3 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) CdvA PF18822.1 EKX31622.1 - 0.0033 17.2 0.9 0.0086 15.9 0.6 1.7 1 1 0 1 1 1 1 CdvA-like coiled-coil domain ApoLp-III PF07464.11 EKX31622.1 - 0.0037 17.4 0.5 0.0058 16.7 0.5 1.2 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) Erp_C PF06780.11 EKX31622.1 - 0.0065 16.5 1.1 0.016 15.2 1.1 1.6 1 0 0 1 1 1 1 Erp protein C-terminus EzrA PF06160.12 EKX31622.1 - 0.0085 14.3 0.0 0.012 13.9 0.0 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Vps53_N PF04100.12 EKX31622.1 - 0.0089 15.0 0.5 0.015 14.3 0.5 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal TPR_MLP1_2 PF07926.12 EKX31622.1 - 0.009 16.1 0.1 0.017 15.2 0.1 1.4 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein IFT57 PF10498.9 EKX31622.1 - 0.01 14.9 0.2 0.014 14.4 0.2 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF1515 PF07439.11 EKX31622.1 - 0.012 15.6 0.3 0.022 14.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) YtxH PF12732.7 EKX31622.1 - 0.013 16.0 5.2 0.44 11.1 5.2 2.3 1 1 0 1 1 1 0 YtxH-like protein bZIP_1 PF00170.21 EKX31622.1 - 0.014 15.5 1.5 0.027 14.5 0.3 2.0 1 1 1 2 2 2 0 bZIP transcription factor Syntaxin-6_N PF09177.11 EKX31622.1 - 0.015 15.9 0.7 0.03 14.9 0.7 1.5 1 0 0 1 1 1 0 Syntaxin 6, N-terminal SKA2 PF16740.5 EKX31622.1 - 0.015 15.1 0.4 0.031 14.0 0.4 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 AAA_13 PF13166.6 EKX31622.1 - 0.015 14.0 0.2 0.02 13.5 0.2 1.1 1 0 0 1 1 1 0 AAA domain DUF2205 PF10224.9 EKX31622.1 - 0.017 15.1 1.1 0.03 14.3 1.1 1.4 1 0 0 1 1 1 0 Short coiled-coil protein HIP1_clath_bdg PF16515.5 EKX31622.1 - 0.017 15.8 0.2 0.031 14.9 0.2 1.4 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fzo_mitofusin PF04799.13 EKX31622.1 - 0.017 14.7 0.4 0.031 13.8 0.4 1.5 1 0 0 1 1 1 0 fzo-like conserved region DivIC PF04977.15 EKX31622.1 - 0.018 14.8 0.6 0.064 13.0 0.1 2.0 1 1 1 2 2 2 0 Septum formation initiator Phasin PF05597.11 EKX31622.1 - 0.019 15.0 1.0 0.036 14.1 1.0 1.4 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) CENP-F_leu_zip PF10473.9 EKX31622.1 - 0.02 14.9 3.0 0.03 14.3 3.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4618 PF15397.6 EKX31622.1 - 0.024 14.1 0.5 0.047 13.1 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) TolA_bind_tri PF16331.5 EKX31622.1 - 0.025 14.7 0.2 0.22 11.6 0.1 2.2 1 1 1 2 2 2 0 TolA binding protein trimerisation Tektin PF03148.14 EKX31622.1 - 0.026 13.3 0.3 0.035 12.9 0.3 1.1 1 0 0 1 1 1 0 Tektin family ZapB PF06005.12 EKX31622.1 - 0.026 15.0 0.6 0.08 13.4 0.3 1.9 1 1 1 2 2 2 0 Cell division protein ZapB DUF4533 PF15047.6 EKX31622.1 - 0.029 14.0 0.4 0.36 10.3 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4533) Fez1 PF06818.15 EKX31622.1 - 0.03 14.8 0.5 0.046 14.2 0.5 1.2 1 0 0 1 1 1 0 Fez1 Prefoldin_2 PF01920.20 EKX31622.1 - 0.031 14.2 1.9 0.061 13.3 0.8 1.9 1 1 1 2 2 2 0 Prefoldin subunit Tup_N PF08581.10 EKX31622.1 - 0.034 14.4 1.5 0.083 13.2 1.5 1.7 1 0 0 1 1 1 0 Tup N-terminal DUF641 PF04859.12 EKX31622.1 - 0.035 14.4 0.2 0.066 13.5 0.2 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) ING PF12998.7 EKX31622.1 - 0.041 14.5 0.5 0.073 13.7 0.5 1.4 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding FlaC_arch PF05377.11 EKX31622.1 - 0.046 14.1 4.5 0.078 13.4 1.2 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) HAUS-augmin3 PF14932.6 EKX31622.1 - 0.047 13.3 0.8 0.067 12.8 0.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Phage_GPO PF05929.11 EKX31622.1 - 0.051 13.2 0.1 0.077 12.6 0.1 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase NPV_P10 PF05531.12 EKX31622.1 - 0.054 14.0 5.9 0.35 11.4 2.7 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein FliD_N PF02465.18 EKX31622.1 - 0.059 14.1 0.5 0.35 11.6 0.4 2.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4164 PF13747.6 EKX31622.1 - 0.061 13.6 0.4 0.12 12.6 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) UPF0449 PF15136.6 EKX31622.1 - 0.063 13.8 2.1 0.12 12.9 2.1 1.8 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 Packaging_FI PF14000.6 EKX31622.1 - 0.077 13.4 1.1 0.15 12.5 1.1 1.4 1 0 0 1 1 1 0 DNA packaging protein FI BLOC1_2 PF10046.9 EKX31622.1 - 0.08 13.3 1.4 0.18 12.2 1.4 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.12 EKX31622.1 - 0.081 12.9 2.0 0.17 11.9 0.8 1.8 1 1 1 2 2 2 0 Laminin Domain II GCN5L1 PF06320.13 EKX31622.1 - 0.089 12.9 0.4 0.15 12.2 0.4 1.3 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) DUF1640 PF07798.11 EKX31622.1 - 0.089 12.8 2.3 0.33 11.0 2.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Seryl_tRNA_N PF02403.22 EKX31622.1 - 0.092 13.0 1.5 0.16 12.2 1.5 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain KxDL PF10241.9 EKX31622.1 - 0.11 12.8 1.3 0.27 11.5 0.3 2.2 2 1 0 2 2 1 0 Uncharacterized conserved protein Occludin_ELL PF07303.13 EKX31622.1 - 0.11 13.3 0.4 0.4 11.4 0.4 1.9 1 1 0 1 1 1 0 Occludin homology domain DivIVA PF05103.13 EKX31622.1 - 0.13 12.3 1.6 0.47 10.5 0.4 2.0 1 1 1 2 2 2 0 DivIVA protein DUF4407 PF14362.6 EKX31622.1 - 0.18 11.1 0.2 0.25 10.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) XhlA PF10779.9 EKX31622.1 - 0.19 11.9 1.8 1.4 9.2 1.8 2.1 1 1 0 1 1 1 0 Haemolysin XhlA Alanine_zipper PF11839.8 EKX31622.1 - 0.2 12.1 0.1 0.7 10.3 0.1 1.9 1 1 1 2 2 1 0 Alanine-zipper, major outer membrane lipoprotein HALZ PF02183.18 EKX31622.1 - 0.23 11.7 6.1 0.21 11.8 0.8 3.3 3 1 1 4 4 2 0 Homeobox associated leucine zipper DUF4795 PF16043.5 EKX31622.1 - 0.47 10.0 4.7 5.2 6.6 0.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Mucin-like PF16058.5 EKX31623.1 - 0.037 14.1 4.3 0.048 13.7 4.3 1.2 1 0 0 1 1 1 0 Mucin-like O-FucT PF10250.9 EKX31626.1 - 0.058 13.1 0.1 0.27 10.9 0.1 1.8 2 0 0 2 2 2 0 GDP-fucose protein O-fucosyltransferase COR PF16095.5 EKX31627.1 - 3.6e-06 26.9 0.0 3.9e-06 26.8 0.0 1.0 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Rdx PF10262.9 EKX31629.1 - 0.0012 19.0 0.0 0.0042 17.3 0.0 1.9 2 0 0 2 2 2 1 Rdx family FliJ PF02050.16 EKX31629.1 - 0.013 15.8 9.8 0.015 15.5 8.2 2.0 1 1 0 1 1 1 0 Flagellar FliJ protein AIP3 PF03915.13 EKX31629.1 - 0.058 12.5 12.8 0.016 14.4 9.0 1.8 1 1 1 2 2 2 0 Actin interacting protein 3 FH2 PF02181.23 EKX31629.1 - 0.17 11.0 8.0 0.14 11.2 6.5 1.4 1 1 0 1 1 1 0 Formin Homology 2 Domain FUSC PF04632.12 EKX31629.1 - 0.27 9.7 4.2 0.38 9.2 4.2 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family CorA PF01544.18 EKX31629.1 - 0.37 10.1 6.4 0.27 10.5 4.0 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF3138 PF11336.8 EKX31629.1 - 0.56 8.8 1.0 0.85 8.2 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Goodbye PF17109.5 EKX31629.1 - 0.97 9.9 4.8 19 5.7 0.0 2.9 2 1 0 2 2 2 0 fungal STAND N-terminal Goodbye domain PAP1 PF08601.10 EKX31629.1 - 1.1 8.9 10.0 2.4 7.8 10.0 1.5 1 1 0 1 1 1 0 Transcription factor PAP1 Sec8_exocyst PF04048.14 EKX31629.1 - 1.2 9.0 6.7 24 4.8 3.4 3.3 3 1 0 3 3 3 0 Sec8 exocyst complex component specific domain DUF948 PF06103.11 EKX31629.1 - 1.3 9.3 4.3 34 4.8 0.6 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 EKX31629.1 - 1.4 8.9 3.6 8.6 6.4 3.4 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HSBP1 PF06825.12 EKX31629.1 - 1.5 8.8 5.2 0.85 9.5 1.3 2.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 UPF0242 PF06785.11 EKX31629.1 - 1.5 8.9 11.6 2.9 8.0 11.6 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ADIP PF11559.8 EKX31629.1 - 1.5 8.9 12.4 5 7.2 12.4 1.9 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 EKX31629.1 - 1.5 8.1 15.9 4.1 6.7 8.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Nckap1 PF09735.9 EKX31629.1 - 2.5 5.9 5.5 0.18 9.7 0.7 1.4 2 0 0 2 2 2 0 Membrane-associated apoptosis protein HIP1_clath_bdg PF16515.5 EKX31629.1 - 3 8.5 24.8 0.29 11.8 11.3 3.5 2 1 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 GAS PF13851.6 EKX31629.1 - 3.1 7.1 13.0 2.4 7.5 9.6 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding kleA_kleC PF17383.2 EKX31629.1 - 4 7.8 7.3 28 5.1 0.5 2.7 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A Spc7 PF08317.11 EKX31629.1 - 4.2 6.2 18.0 0.74 8.6 13.6 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.10 EKX31629.1 - 7.6 6.7 12.0 2.6 8.2 8.3 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family EF-hand_1 PF00036.32 EKX31631.1 - 2.5e-17 61.1 9.1 0.00084 18.7 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EKX31631.1 - 2e-16 60.2 12.7 3.9e-08 33.6 0.8 3.2 1 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EKX31631.1 - 3.8e-14 51.4 14.6 0.00066 19.1 1.0 4.8 4 1 1 5 5 5 4 EF hand EF-hand_6 PF13405.6 EKX31631.1 - 3.1e-12 45.4 10.0 0.002 17.9 0.5 4.5 3 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EKX31631.1 - 2.1e-08 33.9 10.1 0.032 14.1 0.3 4.2 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX31631.1 - 2.6e-06 27.8 4.3 0.0038 17.5 0.2 2.6 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region TPD52 PF04201.15 EKX31631.1 - 0.0021 17.7 1.0 0.0036 16.9 0.3 1.8 2 0 0 2 2 2 1 Tumour protein D52 family FlaC_arch PF05377.11 EKX31631.1 - 0.95 9.9 3.0 0.72 10.3 0.8 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Ipi1_N PF12333.8 EKX31632.1 - 1.2e-08 35.5 0.0 4.9e-08 33.5 0.0 2.2 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation Per1 PF04080.13 EKX31633.1 - 3.8e-59 200.5 13.1 4.4e-59 200.3 13.1 1.0 1 0 0 1 1 1 1 Per1-like family Pentapeptide PF00805.22 EKX31635.1 - 4.4e-108 352.1 97.5 1.4e-09 37.4 0.7 20.5 10 5 7 20 20 20 19 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 EKX31635.1 - 6.4e-76 250.5 19.7 2.8e-10 40.2 0.4 12.9 4 3 8 13 13 13 13 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 EKX31635.1 - 8.3e-52 173.1 31.1 1.7e-05 24.8 0.3 16.8 11 4 4 16 16 16 14 Pentapeptide repeats (9 copies) CfAFP PF05264.11 EKX31635.1 - 0.00049 20.1 8.9 2.9 7.9 0.0 6.4 5 1 1 7 7 7 2 Choristoneura fumiferana antifreeze protein (CfAFP) SPRY PF00622.28 EKX31637.1 - 4.3e-29 101.1 0.2 6.4e-29 100.5 0.2 1.3 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 EKX31637.1 - 5.3e-24 84.8 0.3 7.6e-24 84.3 0.3 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EKX31637.1 - 0.0016 18.3 0.1 0.0048 16.8 0.1 1.8 1 0 0 1 1 1 1 LisH Rpn3_C PF08375.11 EKX31638.1 - 1e-20 73.9 4.9 1e-20 73.9 4.9 2.6 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 EKX31638.1 - 4.4e-18 65.7 1.5 2.5e-17 63.3 0.0 2.8 3 0 0 3 3 3 1 PCI domain DUF3439 PF11921.8 EKX31639.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Sgf11 PF08209.11 EKX31639.1 - 0.97 9.1 3.8 2.6 7.7 3.8 1.8 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) Peptidase_M28 PF04389.17 EKX31641.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 Methyltr_RsmB-F PF01189.17 EKX31642.1 - 4e-72 242.1 0.0 6.2e-72 241.5 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EKX31642.1 - 1.1e-09 38.6 0.0 2.6e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 EKX31642.1 - 8.9e-06 25.9 0.0 1.8e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Met_10 PF02475.16 EKX31642.1 - 0.00084 19.1 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 EKX31642.1 - 0.0022 17.8 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 EKX31642.1 - 0.024 15.4 0.3 0.063 14.0 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 EKX31642.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Phage_holin_2_4 PF16082.5 EKX31642.1 - 0.16 11.7 0.0 0.51 10.1 0.0 1.8 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like RNA_pol_3_Rpc31 PF11705.8 EKX31642.1 - 1.5 9.0 24.4 2.6 8.3 24.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 EKX31642.1 - 3.9 6.7 25.4 6.2 6.1 25.4 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 EKX31642.1 - 8.3 4.5 24.9 13 3.9 24.9 1.2 1 0 0 1 1 1 0 Nop14-like family Atrophin-1 PF03154.15 EKX31642.1 - 8.4 4.5 12.6 12 4.0 12.6 1.1 1 0 0 1 1 1 0 Atrophin-1 family Peptidase_M14 PF00246.24 EKX31643.1 - 8.9e-19 68.4 0.0 2.3e-18 67.0 0.0 1.7 2 1 0 2 2 2 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 EKX31643.1 - 1.4e-11 44.7 1.1 3.7e-11 43.4 1.1 1.7 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Integrase_DNA PF02920.15 EKX31643.1 - 0.066 12.9 0.3 0.24 11.1 0.3 1.9 1 0 0 1 1 1 0 DNA binding domain of tn916 integrase WD40 PF00400.32 EKX31644.1 - 2.9e-22 78.5 15.7 0.00083 20.1 0.5 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX31644.1 - 8e-21 74.2 10.9 0.00092 19.5 0.1 6.6 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 EKX31644.1 - 2.4e-08 33.7 1.2 0.9 8.8 0.0 4.9 1 1 4 5 5 5 3 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 EKX31644.1 - 6e-07 29.2 5.1 3.4 7.7 0.1 5.7 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 EKX31644.1 - 0.0042 15.8 7.9 2.3 6.8 0.1 4.2 4 1 1 5 5 5 2 Nucleoporin Nup120/160 DUF1513 PF07433.11 EKX31644.1 - 0.085 11.9 1.0 30 3.6 0.0 3.9 1 1 4 5 5 5 0 Protein of unknown function (DUF1513) DPPIV_N PF00930.21 EKX31644.1 - 0.17 10.6 2.9 18 3.9 0.1 4.1 1 1 1 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Arena_nucleocap PF00843.17 EKX31644.1 - 0.73 8.7 5.6 1.6 7.6 0.1 3.1 2 2 1 3 3 3 0 Arenavirus nucleocapsid N-terminal domain DUF2499 PF10693.9 EKX31645.1 - 4.1e-38 129.5 4.1 4.6e-38 129.4 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2499) DUF3593 PF12159.8 EKX31646.1 - 6.1e-35 119.1 0.2 6.7e-35 119.0 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3593) DUF5379 PF17350.2 EKX31646.1 - 0.0019 18.4 0.6 0.0022 18.2 0.6 1.3 1 1 0 1 1 1 1 Family of unknown function (DUF5379) ADK PF00406.22 EKX31647.1 - 3.2e-36 124.7 0.0 3.8e-36 124.4 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EKX31647.1 - 2.5e-22 79.8 0.0 2.9e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 EKX31647.1 - 2.3e-06 28.0 0.2 0.0047 17.2 0.1 2.1 1 1 1 2 2 2 2 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 EKX31647.1 - 0.00016 22.3 0.0 0.00022 21.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EKX31647.1 - 0.037 13.3 0.0 0.15 11.3 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 EKX31647.1 - 0.06 13.5 0.0 0.088 13.0 0.0 1.3 1 1 0 1 1 1 0 AAA domain MAF_flag10 PF01973.18 EKX31647.1 - 0.068 12.9 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF115 zf-RING_5 PF14634.6 EKX31648.1 - 1.3e-05 25.0 12.3 1.3e-05 25.0 12.3 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EKX31648.1 - 0.00021 21.3 9.9 0.00074 19.5 9.8 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EKX31648.1 - 0.00023 21.4 13.1 0.00023 21.4 13.1 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EKX31648.1 - 0.0014 18.4 14.3 0.0042 16.9 14.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EKX31648.1 - 0.0027 17.5 13.3 0.0068 16.2 13.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EKX31648.1 - 0.0055 16.5 7.3 0.013 15.4 7.3 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein LysM PF01476.20 EKX31648.1 - 0.0071 16.4 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 LysM domain Multi-haem_cyto PF13447.6 EKX31648.1 - 0.011 15.0 0.1 0.032 13.5 0.1 1.7 1 0 0 1 1 1 0 Seven times multi-haem cytochrome CxxCH Prok-RING_4 PF14447.6 EKX31648.1 - 0.039 13.8 20.1 0.34 10.8 18.6 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF5532 PF17673.1 EKX31648.1 - 0.12 12.5 2.2 0.55 10.3 1.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5532) Gly_acyl_tr_N PF06021.11 EKX31648.1 - 2.1 8.4 8.5 0.49 10.5 2.2 2.5 3 0 0 3 3 3 0 Aralkyl acyl-CoA:amino acid N-acyltransferase zf-RING_4 PF14570.6 EKX31648.1 - 2.7 7.8 12.1 10 6.0 12.1 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 EKX31648.1 - 8.3 6.7 14.6 39 4.5 14.1 2.4 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING CDO_I PF05995.12 EKX31649.1 - 0.021 14.1 0.9 0.05 12.9 0.9 1.6 1 0 0 1 1 1 0 Cysteine dioxygenase type I PDZ_2 PF13180.6 EKX31650.1 - 8.3e-09 35.7 0.0 1.7e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX31650.1 - 3.6e-07 29.9 0.0 7.5e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX31650.1 - 0.00065 20.0 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain SRP54_N PF02881.19 EKX31650.1 - 0.54 10.5 6.5 3.6 7.9 0.3 3.2 4 0 0 4 4 4 0 SRP54-type protein, helical bundle domain Ank_5 PF13857.6 EKX31651.1 - 4.1e-15 55.6 1.5 2.9e-06 27.4 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX31651.1 - 5.7e-15 53.9 0.0 6.4e-05 23.1 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EKX31651.1 - 4.6e-14 52.8 0.1 0.64 10.6 0.0 2.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX31651.1 - 2.4e-13 49.9 0.2 0.0086 16.5 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EKX31651.1 - 4.5e-13 49.4 0.1 2.1e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) INT_SG_DDX_CT_C PF15300.6 EKX31651.1 - 0.022 14.5 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus MFS_1 PF07690.16 EKX31652.1 - 5.5e-27 94.6 23.8 1.2e-21 77.0 18.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EKX31652.1 - 1.3e-08 33.6 20.6 0.00029 19.3 0.1 4.2 2 1 1 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 EKX31652.1 - 4.6e-05 22.5 6.2 4.6e-05 22.5 6.2 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter Phage_Mu_Gam PF07352.12 EKX31653.1 - 0.69 9.8 7.3 2.4 8.0 1.9 2.9 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein SAM_1 PF00536.30 EKX31654.1 - 0.00042 20.7 0.3 0.77 10.2 0.1 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EKX31654.1 - 0.03 14.4 0.1 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) DUF3012 PF11216.8 EKX31654.1 - 0.043 13.8 0.0 0.085 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) Tcf25 PF04910.14 EKX31654.1 - 0.14 11.2 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Transcriptional repressor TCF25 SANT_DAMP1_like PF16282.5 EKX31655.1 - 0.057 13.6 0.4 0.24 11.6 0.3 2.0 1 1 0 1 1 1 0 SANT/Myb-like domain of DAMP1 EMC3_TMCO1 PF01956.16 EKX31656.1 - 2.2e-33 115.4 8.0 2.8e-33 115.1 8.0 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like DUF2237 PF09996.9 EKX31658.1 - 2.1e-08 34.1 1.3 1.8e-07 31.2 1.3 2.1 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) Copine PF07002.16 EKX31659.1 - 1.9e-66 223.6 0.0 2.4e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 EKX31659.1 - 2.5e-10 40.8 0.0 5.6e-10 39.7 0.0 1.5 1 1 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 EKX31659.1 - 0.002 18.4 0.0 0.0043 17.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain JAB PF01398.21 EKX31660.1 - 4.5e-20 71.8 0.1 1e-19 70.6 0.1 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EKX31660.1 - 3.2e-19 69.4 0.1 6.7e-19 68.4 0.0 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function HD PF01966.22 EKX31661.1 - 0.13 12.4 5.9 0.063 13.5 1.2 2.2 1 1 1 2 2 2 0 HD domain DUF2939 PF11159.8 EKX31662.1 - 0.069 13.6 0.1 0.5 10.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) Cornifin PF02389.15 EKX31662.1 - 0.36 11.0 9.1 0.48 10.6 9.1 1.2 1 0 0 1 1 1 0 Cornifin (SPRR) family Carbam_trans_C PF16861.5 EKX31664.1 - 8.1e-62 207.8 0.0 2.1e-61 206.4 0.0 1.6 2 0 0 2 2 2 1 Carbamoyltransferase C-terminus Carbam_trans_N PF02543.15 EKX31664.1 - 9.1e-16 58.4 0.0 1.3e-15 57.9 0.0 1.2 1 0 0 1 1 1 1 Carbamoyltransferase N-terminus Peptidase_M22 PF00814.25 EKX31664.1 - 0.00018 21.3 0.0 0.00024 20.9 0.0 1.2 1 0 0 1 1 1 1 Glycoprotease family DUF4508 PF14969.6 EKX31666.1 - 0.024 14.9 0.3 0.03 14.6 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) DUF1810 PF08837.11 EKX31668.1 - 7.8e-11 41.9 0.0 1.1e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1810) Lipase_3 PF01764.25 EKX31669.1 - 1.3e-06 28.3 0.0 3.8e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Tcp11 PF05794.13 EKX31669.1 - 0.00021 20.5 0.0 0.00044 19.5 0.0 1.5 2 0 0 2 2 2 1 T-complex protein 11 TetR_C_6 PF13977.6 EKX31669.1 - 0.21 11.8 3.3 0.82 9.9 0.8 3.0 3 0 0 3 3 3 0 BetI-type transcriptional repressor, C-terminal ERM PF00769.19 EKX31671.1 - 0.00083 19.2 7.7 0.00083 19.2 7.7 1.9 1 1 0 2 2 2 1 Ezrin/radixin/moesin family Spc7 PF08317.11 EKX31671.1 - 0.0033 16.3 8.6 0.0047 15.8 8.6 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Fez1 PF06818.15 EKX31671.1 - 0.02 15.4 5.9 0.02 15.4 5.9 1.9 1 1 1 2 2 2 0 Fez1 CALCOCO1 PF07888.11 EKX31671.1 - 0.1 11.4 14.7 0.2 10.5 7.1 2.0 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ATG16 PF08614.11 EKX31671.1 - 0.15 12.3 13.9 0.33 11.1 6.9 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 EKX31671.1 - 0.16 11.5 5.9 0.2 11.2 5.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit HMMR_N PF15905.5 EKX31671.1 - 0.22 11.0 10.5 0.23 10.9 4.1 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Flagellin_C PF00700.21 EKX31671.1 - 0.27 11.6 5.0 13 6.2 0.0 3.0 1 1 2 3 3 3 0 Bacterial flagellin C-terminal helical region Atg14 PF10186.9 EKX31671.1 - 0.34 10.0 6.5 0.41 9.7 6.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2968 PF11180.8 EKX31671.1 - 0.54 9.9 12.2 0.1 12.2 5.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) HIP1_clath_bdg PF16515.5 EKX31671.1 - 0.54 10.9 12.4 0.21 12.2 6.8 2.0 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fib_alpha PF08702.10 EKX31671.1 - 0.55 10.4 8.7 0.2 11.9 3.1 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.19 EKX31671.1 - 0.59 8.0 5.7 0.68 7.8 5.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 EKX31671.1 - 0.61 9.4 3.6 0.83 8.9 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ORF6C PF10552.9 EKX31671.1 - 1.3 9.2 6.1 5.5 7.1 0.5 2.3 1 1 2 3 3 3 0 ORF6C domain GTP-bdg_M PF16360.5 EKX31671.1 - 1.5 9.5 7.0 0.25 12.0 1.5 2.1 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region BLOC1_2 PF10046.9 EKX31671.1 - 1.5 9.2 7.4 1.6 9.0 3.2 2.2 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 OmpH PF03938.14 EKX31671.1 - 2.1 8.7 10.5 3.5 7.9 9.3 1.8 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF1664 PF07889.12 EKX31671.1 - 2.6 8.1 6.7 7.3 6.7 6.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.13 EKX31671.1 - 2.7 7.5 7.0 11 5.6 5.6 2.1 1 1 1 2 2 2 0 fzo-like conserved region DUF5595 PF18077.1 EKX31671.1 - 3.1 7.9 6.7 0.65 10.1 1.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) DUF724 PF05266.14 EKX31671.1 - 3.6 7.4 11.9 0.89 9.3 5.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) GBP_C PF02841.14 EKX31671.1 - 4.2 6.7 12.7 5 6.4 12.7 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain LMBR1 PF04791.16 EKX31671.1 - 5.4 5.8 4.8 6.5 5.5 4.8 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein TolA_bind_tri PF16331.5 EKX31673.1 - 0.01 15.9 0.6 0.013 15.6 0.6 1.2 1 0 0 1 1 1 0 TolA binding protein trimerisation Perilipin PF03036.16 EKX31673.1 - 0.092 11.8 0.1 0.099 11.7 0.1 1.0 1 0 0 1 1 1 0 Perilipin family CCCAP PF15964.5 EKX31675.1 - 0.0098 14.2 0.1 0.012 13.9 0.1 1.1 1 0 0 1 1 1 1 Centrosomal colon cancer autoantigen protein family UPF0449 PF15136.6 EKX31675.1 - 0.099 13.1 0.2 0.16 12.5 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Tmemb_cc2 PF10267.9 EKX31675.1 - 0.15 11.1 3.0 0.21 10.7 2.9 1.3 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF3972 PF13118.6 EKX31676.1 - 0.0014 19.1 5.6 0.0074 16.7 0.8 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3972) Prok-TraM PF09228.10 EKX31676.1 - 0.0049 17.2 3.5 0.013 15.8 3.5 1.7 1 0 0 1 1 1 1 Prokaryotic Transcriptional repressor TraM KASH_CCD PF14662.6 EKX31676.1 - 0.0084 16.0 23.2 0.034 14.0 21.5 2.4 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH DivIVA PF05103.13 EKX31676.1 - 0.031 14.4 1.6 0.031 14.4 1.6 3.1 2 1 0 2 2 2 0 DivIVA protein Imm7 PF15585.6 EKX31676.1 - 0.059 13.7 0.3 0.29 11.4 0.0 2.3 2 1 1 3 3 3 0 Immunity protein 7 FadA PF09403.10 EKX31676.1 - 0.16 12.4 9.5 0.59 10.7 4.4 2.5 2 0 0 2 2 2 0 Adhesion protein FadA TMF_TATA_bd PF12325.8 EKX31676.1 - 0.23 11.7 21.2 0.16 12.2 5.9 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding bZIP_1 PF00170.21 EKX31676.1 - 0.24 11.5 20.4 1.5 9.0 0.3 4.3 1 1 3 4 4 4 0 bZIP transcription factor DUF3450 PF11932.8 EKX31676.1 - 0.5 9.6 17.7 0.087 12.1 3.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 EKX31676.1 - 2.8 8.1 21.8 9.4 6.4 21.8 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 EKX31676.1 - 3.3 7.7 23.3 0.18 11.8 12.0 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 EKX31676.1 - 4.4 8.0 15.8 9.1 7.0 5.8 2.8 1 1 1 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 EKX31676.1 - 6.4 7.3 30.7 3.6 8.1 4.3 3.6 2 1 1 3 3 2 0 Cell division protein ZapB ABC_tran_CTD PF16326.5 EKX31676.1 - 7.3 6.9 14.5 5.1 7.4 0.5 2.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain Lipase_3 PF01764.25 EKX31677.1 - 0.00057 19.8 0.0 0.00096 19.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Tcp11 PF05794.13 EKX31678.1 - 2.4e-15 56.6 0.0 7.3e-15 55.0 0.0 1.5 1 1 0 1 1 1 1 T-complex protein 11 Lipase_3 PF01764.25 EKX31678.1 - 0.00039 20.3 0.0 0.00082 19.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF5338 PF17273.2 EKX31678.1 - 0.13 12.3 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5338) Reticulon PF02453.17 EKX31682.1 - 1.8e-20 73.5 0.6 2.1e-20 73.3 0.6 1.1 1 0 0 1 1 1 1 Reticulon CDC14 PF08045.11 EKX31683.1 - 0.11 11.6 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 Cell division control protein 14, SIN component 12TM_1 PF09847.9 EKX31684.1 - 0.0071 15.5 8.7 0.012 14.8 8.7 1.3 1 0 0 1 1 1 1 Membrane protein of 12 TMs UPF0242 PF06785.11 EKX31684.1 - 0.043 13.9 1.8 0.086 12.9 1.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4351 PF14261.6 EKX31684.1 - 0.072 13.2 0.3 0.19 11.8 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) YtpI PF14007.6 EKX31684.1 - 1.3 9.2 6.4 5.1 7.3 0.1 3.0 2 1 1 3 3 3 0 YtpI-like protein V-ATPase_H_C PF11698.8 EKX31685.1 - 2.2e-29 101.9 0.5 5.2e-29 100.7 0.3 1.7 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_N PF03224.14 EKX31685.1 - 0.00081 18.8 0.2 0.13 11.5 0.0 2.4 2 0 0 2 2 2 2 V-ATPase subunit H CP12 PF02672.15 EKX31685.1 - 0.11 13.3 0.1 23 5.8 0.0 2.6 2 0 0 2 2 2 0 CP12 domain PilJ PF13675.6 EKX31686.1 - 0.32 11.0 3.1 1.1 9.3 0.2 2.7 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term LRR_8 PF13855.6 EKX31687.1 - 2.3e-23 81.7 1.4 1.2e-16 60.2 0.6 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EKX31687.1 - 9.2e-13 48.2 7.4 8.3e-07 29.2 0.7 2.6 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX31687.1 - 4.1e-07 30.0 0.0 7.4e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 EKX31687.1 - 0.00031 20.6 3.8 4.8 7.5 0.2 4.0 3 0 0 3 3 3 3 Leucine Rich repeat LRR_1 PF00560.33 EKX31687.1 - 0.00031 20.9 0.2 1 10.2 0.1 3.8 3 0 0 3 3 3 1 Leucine Rich Repeat Mfp-3 PF04202.13 EKX31687.1 - 0.14 12.6 1.7 59 4.1 0.0 3.3 3 0 0 3 3 3 0 Foot protein 3 Sec23_trunk PF04811.15 EKX31688.1 - 4.6e-36 124.6 0.0 7.3e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 EKX31688.1 - 5.6e-10 39.1 0.1 1.3e-09 37.9 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 EKX31688.1 - 2.9e-08 34.4 0.0 8e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EKX31688.1 - 0.0027 17.5 0.3 0.0051 16.6 0.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain DUF1720 PF08226.11 EKX31688.1 - 0.0066 16.8 10.0 0.0066 16.8 10.0 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1720) ABC_tran PF00005.27 EKX31689.1 - 1.2e-24 87.4 0.0 2.6e-24 86.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EKX31689.1 - 2.8e-22 79.3 20.5 2.8e-22 79.3 20.5 1.9 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 EKX31689.1 - 7.2e-11 42.4 0.1 2.7e-07 30.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 EKX31689.1 - 1.4e-05 24.6 19.1 0.085 12.3 19.6 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC2_membrane_2 PF12679.7 EKX31689.1 - 0.0021 17.4 6.5 0.0039 16.5 6.5 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_23 PF13476.6 EKX31689.1 - 0.0023 18.5 0.1 0.0047 17.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain DUF4162 PF13732.6 EKX31689.1 - 0.082 13.6 0.2 0.21 12.3 0.0 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4162) SMC_N PF02463.19 EKX31689.1 - 0.095 12.1 0.0 2.1 7.7 0.0 2.3 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EKX31689.1 - 0.11 12.2 0.0 1.9 8.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 EKX31689.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Rad17 PF03215.15 EKX31689.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Mg_chelatase PF01078.21 EKX31689.1 - 0.15 11.5 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EKX31689.1 - 0.18 12.1 0.0 0.75 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EKX31689.1 - 0.21 11.3 0.1 0.61 9.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain Pet100 PF09803.9 EKX31690.1 - 2.4 8.8 5.5 1.4 9.5 0.1 3.1 2 0 0 2 2 2 0 Pet100 Copine PF07002.16 EKX31691.1 - 5.7e-71 238.4 0.1 1e-70 237.6 0.0 1.4 2 0 0 2 2 2 1 Copine C2 PF00168.30 EKX31691.1 - 9.7e-24 83.6 0.7 4.1e-13 49.5 0.1 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 EKX31691.1 - 7.4e-10 39.3 0.0 1.5e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 EKX31691.1 - 0.00013 22.2 0.1 0.00042 20.6 0.1 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EKX31691.1 - 0.013 15.5 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain Oxysterol_BP PF01237.18 EKX31692.1 - 3.7e-58 197.1 0.2 5.7e-56 190.0 0.2 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein DUF4874 PF16173.5 EKX31692.1 - 0.038 13.7 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) Copine PF07002.16 EKX31693.1 - 4.8e-70 235.4 0.1 6.5e-70 235.0 0.1 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 EKX31693.1 - 2.2e-22 79.3 0.2 1.2e-11 44.8 0.1 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 EKX31693.1 - 2.5e-10 40.8 0.0 5e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 EKX31693.1 - 3.6e-05 24.1 0.0 9.3e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EKX31693.1 - 0.0015 18.5 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Copine PF07002.16 EKX31694.1 - 2.4e-71 239.6 0.2 4.5e-71 238.8 0.1 1.5 2 0 0 2 2 2 1 Copine C2 PF00168.30 EKX31694.1 - 5.4e-24 84.5 1.1 4.9e-13 49.2 0.1 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 EKX31694.1 - 1.3e-09 38.5 0.0 2.5e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 EKX31694.1 - 9e-05 22.8 0.1 0.00023 21.5 0.1 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EKX31694.1 - 0.0093 15.9 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain BIR PF00653.21 EKX31695.1 - 4.3e-17 62.5 0.0 8.7e-17 61.5 0.0 1.5 1 1 0 1 1 1 1 Inhibitor of Apoptosis domain DegT_DnrJ_EryC1 PF01041.17 EKX31697.1 - 2.7e-66 224.3 0.0 3.1e-66 224.1 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family LAS2 PF15792.5 EKX31699.1 - 0.052 14.1 0.3 13 6.4 0.1 2.5 2 0 0 2 2 2 0 Lung adenoma susceptibility protein 2 DnaJ PF00226.31 EKX31700.1 - 1.8e-28 98.4 1.8 3.1e-28 97.7 1.8 1.4 1 0 0 1 1 1 1 DnaJ domain DUF4460 PF14687.6 EKX31700.1 - 0.036 14.1 0.5 0.073 13.1 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4460) JTB PF05439.12 EKX31702.1 - 0.081 13.0 0.2 0.19 11.8 0.2 1.5 1 0 0 1 1 1 0 Jumping translocation breakpoint protein (JTB) Amino_oxidase PF01593.24 EKX31703.1 - 4.8e-44 151.4 0.0 9.2e-28 97.7 0.0 3.0 1 1 1 3 3 3 3 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EKX31703.1 - 9e-10 38.6 0.0 1.7e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EKX31703.1 - 8.6e-05 22.1 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EKX31703.1 - 0.00016 21.4 0.2 0.00034 20.3 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EKX31703.1 - 0.00077 18.8 0.0 0.0016 17.8 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EKX31703.1 - 0.0015 19.0 0.2 0.05 14.2 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EKX31703.1 - 0.0017 17.1 0.2 0.0028 16.4 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EKX31703.1 - 0.0022 17.3 0.0 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EKX31703.1 - 0.0034 16.7 0.2 0.0063 15.8 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EKX31703.1 - 0.0084 15.2 0.4 0.028 13.5 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain IlvN PF07991.12 EKX31703.1 - 0.02 14.5 0.1 0.038 13.6 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 EKX31703.1 - 0.021 14.9 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.14 EKX31703.1 - 0.044 12.6 0.2 0.072 11.9 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 EKX31703.1 - 0.063 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 EKX31703.1 - 0.063 12.5 0.1 0.096 11.9 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Phage_Coat_Gp8 PF05371.12 EKX31703.1 - 0.098 12.4 0.6 0.81 9.5 0.6 2.3 2 0 0 2 2 2 0 Phage major coat protein, Gp8 TrkA_N PF02254.18 EKX31703.1 - 0.1 12.9 0.1 0.26 11.6 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain Cupin_8 PF13621.6 EKX31704.1 - 0.14 11.9 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Cupin-like domain DUF1090 PF06476.12 EKX31705.1 - 0.0001 22.4 58.1 0.059 13.5 5.9 6.2 3 2 3 6 6 6 5 Protein of unknown function (DUF1090) RPT PF13446.6 EKX31705.1 - 0.00012 21.9 0.1 5.9 6.9 0.0 4.6 3 2 2 5 5 5 2 A repeated domain in UCH-protein FabA PF07977.13 EKX31705.1 - 0.27 10.8 10.4 1.6 8.4 0.4 3.6 2 2 1 3 3 3 0 FabA-like domain DUF1640 PF07798.11 EKX31705.1 - 0.4 10.7 13.1 0.71 9.9 1.0 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) HTH_53 PF18606.1 EKX31705.1 - 0.56 9.9 16.2 18 5.1 0.1 6.6 3 2 5 8 8 8 0 Zap helix turn helix N-terminal domain DUF3034 PF11231.8 EKX31705.1 - 1.8 8.1 10.2 1.8 8.0 2.6 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3034) EF-hand_8 PF13833.6 EKX31706.1 - 0.00013 21.8 1.8 0.0056 16.5 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX31706.1 - 0.0002 20.6 7.2 0.76 9.5 0.0 4.3 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 EKX31706.1 - 0.011 16.2 2.9 0.16 12.5 0.7 2.5 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 EKX31706.1 - 0.051 13.5 2.6 5.9 7.1 0.1 3.6 3 1 0 3 3 3 0 EF-hand domain KxDL PF10241.9 EKX31707.1 - 0.0033 17.7 3.1 0.0033 17.7 3.1 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein APG6_N PF17675.1 EKX31707.1 - 0.0077 16.8 9.8 0.0084 16.6 9.1 1.4 1 1 0 1 1 1 1 Apg6 coiled-coil region DUF4495 PF14906.6 EKX31707.1 - 0.039 13.0 0.5 0.05 12.7 0.4 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4495) DUF724 PF05266.14 EKX31707.1 - 0.076 12.8 8.0 0.087 12.6 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) PCRF PF03462.18 EKX31707.1 - 0.094 12.6 3.6 0.1 12.4 3.6 1.2 1 0 0 1 1 1 0 PCRF domain YbfN PF13982.6 EKX31707.1 - 0.1 12.9 1.1 0.33 11.3 0.1 2.0 2 0 0 2 2 2 0 YbfN-like lipoprotein DUF3086 PF11285.8 EKX31707.1 - 0.11 11.6 3.3 0.12 11.4 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) CorA PF01544.18 EKX31707.1 - 0.19 11.0 4.1 0.21 10.9 4.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF3450 PF11932.8 EKX31707.1 - 0.37 10.0 8.5 1.4 8.2 2.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 EKX31707.1 - 0.51 9.2 13.3 0.77 8.6 13.3 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 EKX31707.1 - 0.52 10.4 4.8 0.52 10.4 3.7 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 EKX31707.1 - 0.52 10.4 13.7 1.5 8.9 10.6 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein TMPIT PF07851.13 EKX31707.1 - 1.5 8.0 8.2 1.6 7.9 8.2 1.0 1 0 0 1 1 1 0 TMPIT-like protein MRPL52 PF18699.1 EKX31707.1 - 2.5 8.4 7.9 0.43 10.8 3.6 1.8 2 0 0 2 2 2 0 Mitoribosomal protein mL52 HAUS6_N PF14661.6 EKX31707.1 - 5.4 6.5 10.4 1.6 8.2 3.4 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Ribosomal_L35Ae PF01247.18 EKX31708.1 - 4.9e-44 148.4 0.3 6.9e-44 147.9 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 EKX31708.1 - 0.00098 19.3 0.2 0.68 10.2 0.0 2.4 2 0 0 2 2 2 2 RimM N-terminal domain Kinesin PF00225.23 EKX31709.1 - 2.2e-75 253.7 0.4 2.6e-75 253.4 0.4 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX31709.1 - 2e-18 66.7 0.0 5.4e-18 65.3 0.0 1.7 2 0 0 2 2 2 1 Microtubule binding GREB1 PF15782.5 EKX31714.1 - 1.8e-10 38.7 15.4 3.3e-08 31.3 0.0 4.5 5 1 0 5 5 5 3 Gene regulated by oestrogen in breast cancer Dicty_REP PF05086.12 EKX31714.1 - 3.5 5.5 7.8 5.1 4.9 7.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF745 PF05335.13 EKX31716.1 - 0.00027 20.7 4.4 0.00027 20.7 4.4 3.6 2 1 2 4 4 4 1 Protein of unknown function (DUF745) AAA_15 PF13175.6 EKX31716.1 - 0.73 9.5 9.4 1.9 8.1 9.4 1.6 1 0 0 1 1 1 0 AAA ATPase domain TPH PF13868.6 EKX31717.1 - 2.6e-57 194.0 167.1 2.6e-57 194.0 167.1 2.2 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain SlyX PF04102.12 EKX31718.1 - 0.49 11.0 10.1 0.24 12.0 3.7 2.8 2 0 0 2 2 2 0 SlyX 2_5_RNA_ligase2 PF13563.6 EKX31720.1 - 0.024 14.5 2.9 0.43 10.5 1.3 3.1 2 1 0 2 2 2 0 2'-5' RNA ligase superfamily Fez1 PF06818.15 EKX31720.1 - 0.56 10.6 54.4 5 7.5 15.8 3.5 1 1 3 4 4 4 0 Fez1 HlyD_2 PF12700.7 EKX31720.1 - 3.9 6.1 14.7 0.12 11.1 2.3 2.3 2 1 0 2 2 2 0 HlyD family secretion protein Atg14 PF10186.9 EKX31720.1 - 6.1 5.8 42.8 0.32 10.0 4.6 3.8 2 2 2 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2533 PF10752.9 EKX31720.1 - 8.1 7.0 9.2 0.71 10.3 0.2 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2533) TTC5_OB PF16669.5 EKX31722.1 - 7.5e-11 41.7 0.0 1.2e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat protein 5 OB fold domain TPR_2 PF07719.17 EKX31722.1 - 9e-11 41.0 6.7 0.005 16.9 0.2 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX31722.1 - 1.3e-10 40.6 6.5 0.049 13.5 0.0 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EKX31722.1 - 4.5e-08 32.9 0.1 0.057 13.8 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX31722.1 - 1.6e-06 28.6 0.8 0.0063 17.1 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX31722.1 - 2.6e-06 27.2 1.4 0.4 11.0 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX31722.1 - 7.6e-06 25.5 0.1 0.028 14.1 0.0 3.7 3 1 1 4 4 4 2 TPR repeat TPR_12 PF13424.6 EKX31722.1 - 0.00036 20.8 0.6 0.27 11.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX31722.1 - 0.0028 17.8 3.3 2.8 8.2 0.4 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat NPH3 PF03000.14 EKX31722.1 - 0.01 15.5 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 NPH3 family TPR_14 PF13428.6 EKX31722.1 - 0.011 16.5 1.9 5.9 8.0 0.1 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX31722.1 - 0.027 14.9 2.8 0.34 11.5 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat SBP_bac_3 PF00497.20 EKX31723.1 - 4.9e-25 88.3 0.0 7.7e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 CM_1 PF07736.11 EKX31723.1 - 2.7e-22 79.3 0.0 4.6e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Chorismate mutase type I Glyoxalase PF00903.25 EKX31724.1 - 7.9e-05 22.8 0.1 8.9e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Acetyltransf_10 PF13673.7 EKX31724.1 - 0.0024 17.8 0.0 0.0031 17.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyoxalase_4 PF13669.6 EKX31724.1 - 0.013 15.8 0.0 0.016 15.5 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EKX31724.1 - 0.14 12.3 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain Sema PF01403.19 EKX31725.1 - 0.097 11.5 0.1 0.19 10.5 0.1 1.4 1 0 0 1 1 1 0 Sema domain p450 PF00067.22 EKX31726.1 - 5.4e-59 200.1 0.1 7.2e-59 199.7 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 TPR_14 PF13428.6 EKX31727.1 - 1.1e-16 60.1 9.3 0.0056 17.4 0.3 7.8 5 3 4 9 9 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 EKX31727.1 - 3.9e-15 55.0 18.9 0.0082 16.4 0.2 7.5 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 EKX31727.1 - 4e-14 52.0 18.0 0.0016 18.0 4.8 7.4 5 1 2 7 7 7 5 TPR repeat TPR_8 PF13181.6 EKX31727.1 - 3.2e-12 45.6 28.7 0.013 15.6 0.0 8.8 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 EKX31727.1 - 2.9e-11 43.5 20.0 0.007 16.6 3.0 6.0 4 1 3 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 EKX31727.1 - 1.3e-09 37.4 23.5 0.01 15.9 1.4 8.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 EKX31727.1 - 2.3e-09 36.7 30.3 0.091 12.6 3.4 9.4 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 EKX31727.1 - 4.2e-07 30.4 10.8 0.05 14.1 1.3 5.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX31727.1 - 3.2e-05 24.5 5.0 0.17 12.5 1.7 4.7 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX31727.1 - 0.0011 19.1 2.8 4 7.7 0.1 4.7 2 1 4 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX31727.1 - 0.0046 17.5 14.1 21 6.0 0.7 6.5 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX31727.1 - 0.011 15.5 16.3 0.49 10.3 0.9 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Viral_RdRp_C PF17501.2 EKX31727.1 - 0.082 13.4 1.0 0.18 12.3 1.0 1.5 1 0 0 1 1 1 0 Viral RNA-directed RNA polymerase TPR_7 PF13176.6 EKX31727.1 - 0.084 12.9 14.7 65 3.9 0.0 7.0 5 2 1 6 6 6 0 Tetratricopeptide repeat Ephrin_rec_like PF07699.13 EKX31729.1 - 1e-44 150.1 92.9 2.1e-09 37.0 8.0 9.2 4 1 5 9 9 9 9 Putative ephrin-receptor like EGF_MSP1_1 PF12946.7 EKX31729.1 - 0.031 14.3 15.7 0.5 10.5 0.9 4.3 4 0 0 4 4 4 0 MSP1 EGF domain 1 DUF4596 PF15363.6 EKX31729.1 - 0.81 10.0 7.0 7.5 6.9 0.4 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4596) Sulfotransfer_1 PF00685.27 EKX31732.1 - 0.029 13.8 0.2 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 Sulfotransferase domain Jas PF16135.5 EKX31732.1 - 0.048 13.8 0.0 0.46 10.7 0.0 2.2 2 0 0 2 2 2 0 TPL-binding domain in jasmonate signalling DNA_ligase_A_M PF01068.21 EKX31732.1 - 0.16 11.6 0.1 0.29 10.8 0.1 1.3 1 0 0 1 1 1 0 ATP dependent DNA ligase domain Ephrin_rec_like PF07699.13 EKX31733.1 - 3.3e-227 734.3 1068.5 1.1e-09 37.9 2.1 93.6 66 17 33 100 100 100 80 Putative ephrin-receptor like EGF_CA PF07645.15 EKX31733.1 - 8.5e-28 96.3 65.6 3.7e-10 39.9 6.0 63.7 62 18 14 76 76 76 5 Calcium-binding EGF domain EGF_3 PF12947.7 EKX31733.1 - 6.1e-12 45.5 33.7 3.9e-07 30.2 10.4 51.7 56 0 0 56 56 56 8 EGF domain cEGF PF12662.7 EKX31733.1 - 4.7e-09 36.0 10.8 6.7e-05 22.7 0.3 69.3 73 4 1 74 74 74 17 Complement Clr-like EGF-like EGF PF00008.27 EKX31733.1 - 0.00059 20.1 17.8 0.00073 19.8 6.0 46.4 55 0 0 55 55 55 8 EGF-like domain FXa_inhibition PF14670.6 EKX31733.1 - 0.0034 17.6 5.4 0.0034 17.6 5.4 69.0 67 13 12 79 79 79 4 Coagulation Factor Xa inhibitory site hEGF PF12661.7 EKX31733.1 - 0.0038 17.8 6.1 0.0038 17.8 6.1 52.2 59 0 0 59 59 59 9 Human growth factor-like EGF Drf_FH1 PF06346.12 EKX31734.1 - 0.00056 19.7 29.0 0.00066 19.4 29.0 1.1 1 0 0 1 1 1 1 Formin Homology Region 1 DDE_Tnp_4 PF13359.6 EKX31737.1 - 3.7e-18 65.7 0.0 4.2e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EKX31737.1 - 0.00027 20.7 0.0 0.00039 20.1 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain E7 PF00527.18 EKX31738.1 - 0.29 11.4 4.2 0.28 11.4 0.8 2.4 1 1 1 2 2 2 0 E7 protein, Early protein Methyltransf_21 PF05050.12 EKX31742.1 - 7.4e-11 42.4 0.0 1.3e-10 41.6 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase FkbM domain EGF_CA PF07645.15 EKX31744.1 - 0.0063 16.7 1.9 0.016 15.4 1.9 1.7 1 0 0 1 1 1 1 Calcium-binding EGF domain CagY_M PF07337.11 EKX31745.1 - 0.022 14.3 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 DC-EC Repeat DUF4615 PF15393.6 EKX31746.1 - 0.1 13.2 0.1 0.16 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) Herpes_UL92 PF03048.14 EKX31747.1 - 9.2e-08 32.1 1.5 9.2e-08 32.1 1.5 3.1 3 1 1 4 4 4 1 UL92 family Pkinase PF00069.25 EKX31751.1 - 4.9e-36 124.5 0.0 2.1e-23 83.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EKX31751.1 - 3.8e-18 65.7 0.0 2.8e-14 53.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX31751.1 - 0.0065 15.3 0.0 0.013 14.4 0.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX31751.1 - 0.012 15.6 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EKX31751.1 - 0.014 14.7 0.1 0.024 14.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EKX31751.1 - 0.056 13.1 0.1 0.45 10.1 0.1 2.3 2 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 EKX31751.1 - 0.099 12.2 0.1 0.42 10.2 0.1 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase CagA PF03507.13 EKX31753.1 - 0.023 14.6 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 CagA exotoxin Intron_maturas2 PF01348.21 EKX31753.1 - 0.13 12.3 0.2 0.35 10.8 0.2 1.7 1 0 0 1 1 1 0 Type II intron maturase C2 PF00168.30 EKX31755.1 - 1.1e-11 44.9 0.0 1.1e-11 44.9 0.0 1.0 1 0 0 1 1 1 1 C2 domain Ribosomal_S9 PF00380.19 EKX31756.1 - 4.4e-33 114.4 0.4 5e-33 114.2 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 FAD_binding_1 PF00667.20 EKX31757.1 - 1.1e-63 214.8 0.0 1.6e-63 214.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EKX31757.1 - 1.3e-31 109.7 0.3 2.5e-31 108.8 0.3 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EKX31757.1 - 2.8e-17 63.3 0.0 6e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Carn_acyltransf PF00755.20 EKX31758.1 - 1.6e-171 571.9 0.3 1.8e-171 571.7 0.3 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase RNase_P_p30 PF01876.16 EKX31759.1 - 4.9e-43 147.1 0.0 8.4e-43 146.3 0.0 1.4 1 0 0 1 1 1 1 RNase P subunit p30 Aminotran_1_2 PF00155.21 EKX31760.1 - 8.5e-58 196.3 0.0 9.8e-58 196.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EKX31760.1 - 1.8e-07 30.8 0.0 3.2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EKX31760.1 - 4.7e-06 25.4 0.0 7.4e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EKX31760.1 - 0.00012 21.5 0.0 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EKX31760.1 - 0.00039 19.5 0.0 0.00077 18.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DUF4384 PF14326.6 EKX31760.1 - 0.0061 16.6 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4384) Met_gamma_lyase PF06838.11 EKX31760.1 - 0.079 11.5 0.0 0.14 10.7 0.0 1.3 1 0 0 1 1 1 0 Methionine gamma-lyase Use1 PF09753.9 EKX31761.1 - 1.3e-14 54.6 31.5 2.9e-14 53.4 16.6 2.9 2 1 0 2 2 2 1 Membrane fusion protein Use1 Orf78 PF06024.12 EKX31761.1 - 0.0021 18.3 1.4 0.0021 18.3 1.4 3.1 2 1 1 3 3 3 1 Orf78 (ac78) DUF1676 PF07898.13 EKX31761.1 - 0.0024 17.9 10.5 0.0024 17.9 10.5 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF1676) DUF5345 PF17280.2 EKX31761.1 - 0.0025 17.8 3.6 0.35 10.9 0.2 2.8 2 0 0 2 2 2 2 Family of unknown function (DUF5345) DUF2207 PF09972.9 EKX31761.1 - 0.0057 15.5 0.1 0.0083 14.9 0.1 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) PBP1_TM PF14812.6 EKX31761.1 - 0.0086 16.4 26.7 0.019 15.3 10.9 3.4 3 1 0 3 3 3 2 Transmembrane domain of transglycosylase PBP1 at N-terminal Peroxin-13_N PF04088.13 EKX31761.1 - 0.028 14.7 2.2 0.028 14.7 2.2 2.7 2 1 1 3 3 3 0 Peroxin 13, N-terminal region DUF2031 PF09592.10 EKX31761.1 - 0.1 12.1 6.3 0.084 12.4 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2031) DUF4448 PF14610.6 EKX31761.1 - 0.15 11.9 0.5 0.35 10.6 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) LAP1C PF05609.12 EKX31761.1 - 0.18 10.9 23.0 0.95 8.5 2.3 2.2 1 1 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) AgrB PF04647.15 EKX31761.1 - 0.19 11.1 6.7 0.29 10.4 1.7 2.1 2 0 0 2 2 2 0 Accessory gene regulator B DUF5316 PF17247.2 EKX31761.1 - 0.19 11.8 4.0 2.1 8.4 0.7 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5316) T2SSF PF00482.23 EKX31761.1 - 0.4 10.6 13.6 0.31 11.0 6.8 3.1 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF5383 PF17355.2 EKX31761.1 - 0.54 10.6 12.1 0.44 10.9 0.4 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5383) CENP-B_dimeris PF09026.10 EKX31761.1 - 0.77 10.2 7.2 2.2 8.7 7.2 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2116 PF09889.9 EKX31761.1 - 1.2 9.2 17.7 0.92 9.5 11.8 2.4 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Sec20 PF03908.13 EKX31761.1 - 1.4 8.9 6.3 0.84 9.6 0.2 2.8 3 0 0 3 3 2 0 Sec20 DUF1129 PF06570.11 EKX31761.1 - 1.7 8.1 8.8 6.4 6.2 6.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) GWT1 PF06423.12 EKX31761.1 - 1.8 8.7 5.2 4.8 7.3 0.8 2.3 1 1 1 2 2 2 0 GWT1 EMC3_TMCO1 PF01956.16 EKX31761.1 - 3 7.6 17.0 1.7 8.4 10.8 2.5 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like DUF3357 PF11837.8 EKX31761.1 - 3.5 8.1 5.9 12 6.4 0.9 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) ETRAMP PF09716.10 EKX31761.1 - 4 7.6 7.2 19 5.4 7.6 2.2 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) MIF4G_like_2 PF09090.11 EKX31761.1 - 5.9 6.3 10.2 0.72 9.3 0.6 2.4 2 0 0 2 2 2 0 MIF4G like DUF2206 PF09971.9 EKX31761.1 - 7 5.3 7.6 12 4.5 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2206) DUF4366 PF14283.6 EKX31761.1 - 9.1 6.3 13.5 0.51 10.4 1.8 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) CENP-Q PF13094.6 EKX31762.1 - 0.01 16.0 2.3 0.01 16.0 2.3 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Ribosomal_L4 PF00573.22 EKX31763.1 - 1.2e-54 185.0 0.4 1.7e-54 184.4 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family PH PF00169.29 EKX31764.1 - 1.9e-11 44.4 0.4 2.2e-11 44.2 0.4 1.0 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EKX31764.1 - 3.8e-05 24.1 1.4 0.001 19.5 1.4 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.10 EKX31764.1 - 0.021 15.2 0.2 0.026 14.9 0.2 1.4 1 1 0 1 1 1 0 Plant pleckstrin homology-like region PH_8 PF15409.6 EKX31764.1 - 0.026 14.8 0.6 0.098 13.0 0.6 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain SET PF00856.28 EKX31766.1 - 1.3e-10 41.9 0.1 1.4e-08 35.3 0.0 2.4 2 0 0 2 2 2 1 SET domain CDC45 PF02724.14 EKX31766.1 - 0.025 12.9 4.8 0.04 12.2 4.8 1.3 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 EKX31766.1 - 0.038 13.3 7.6 0.063 12.6 7.6 1.2 1 0 0 1 1 1 0 NOA36 protein GCIP PF13324.6 EKX31766.1 - 0.081 12.5 6.3 0.13 11.8 6.3 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting CENP-B_dimeris PF09026.10 EKX31766.1 - 0.74 10.2 10.9 2 8.8 10.9 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RPA43_OB PF17875.1 EKX31766.1 - 1.9 9.1 5.6 0.45 11.2 2.3 1.6 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I DUF4637 PF15470.6 EKX31766.1 - 6.9 6.4 8.5 18 5.0 8.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Hydrolase_4 PF12146.8 EKX31767.1 - 8.2e-07 28.5 0.2 1.2e-06 28.0 0.2 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EKX31767.1 - 0.00023 21.8 0.0 0.00031 21.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EKX31767.1 - 0.0007 19.3 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Tctex-1 PF03645.13 EKX31768.1 - 9.5e-32 109.3 0.6 1.1e-31 109.1 0.6 1.1 1 0 0 1 1 1 1 Tctex-1 family DUF4558 PF15104.6 EKX31769.1 - 2.8e-09 36.9 6.8 3.4e-09 36.6 6.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4558) DUF3287 PF11690.8 EKX31769.1 - 0.015 15.0 0.8 0.018 14.7 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) Peptidase_C12 PF01088.21 EKX31771.1 - 9e-59 198.7 0.0 1e-58 198.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Fib_alpha PF08702.10 EKX31772.1 - 0.0089 16.2 3.5 0.26 11.5 2.4 2.2 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family CppA_N PF14506.6 EKX31772.1 - 0.02 14.9 1.1 0.037 14.1 1.1 1.3 1 0 0 1 1 1 0 CppA N-terminal WD-3 PF09765.9 EKX31772.1 - 0.045 13.1 0.8 0.13 11.5 0.7 1.7 1 1 0 1 1 1 0 WD-repeat region Asp-B-Hydro_N PF05279.11 EKX31772.1 - 0.39 10.8 7.2 0.5 10.4 7.2 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region MPS2 PF17060.5 EKX31772.1 - 0.47 9.7 8.6 0.31 10.3 5.6 1.7 1 1 0 2 2 2 0 Monopolar spindle protein 2 Spc7 PF08317.11 EKX31772.1 - 0.51 9.2 13.6 0.068 12.1 7.0 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Z1 PF10593.9 EKX31772.1 - 0.87 9.0 4.4 1.4 8.3 4.4 1.5 1 1 0 1 1 1 0 Z1 domain ADIP PF11559.8 EKX31772.1 - 2 8.5 13.2 4.4 7.4 0.9 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 EKX31772.1 - 8.1 7.1 10.2 21 5.8 0.5 3.3 2 1 1 3 3 3 0 SlyX Pkinase_Tyr PF07714.17 EKX31774.1 - 5e-39 134.1 0.0 6.1e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX31774.1 - 3.6e-26 92.1 0.0 4.2e-26 91.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EKX31774.1 - 1.8e-07 30.7 0.0 2.1e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EKX31774.1 - 0.031 13.9 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 EKX31774.1 - 0.063 12.0 0.0 0.073 11.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase U-box PF04564.15 EKX31775.1 - 8.2e-18 64.4 0.0 8.7e-18 64.3 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX31775.1 - 3.7e-05 23.4 0.0 5.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 EKX31775.1 - 0.00025 21.1 0.0 0.00034 20.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein GYF_2 PF14237.6 EKX31778.1 - 1.1e-12 47.5 3.8 1.6e-12 47.0 0.5 2.7 3 0 0 3 3 3 1 GYF domain 2 RRM_1 PF00076.22 EKX31778.1 - 1.1e-06 28.4 0.2 0.01 15.7 0.1 3.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.26 EKX31778.1 - 0.00011 22.3 4.1 0.00011 22.3 4.1 3.2 4 0 0 4 4 4 1 WW domain Peptidase_S49_N PF08496.10 EKX31778.1 - 1.5 8.9 5.0 11 6.1 0.7 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal AP3D1 PF06375.11 EKX31778.1 - 5.9 7.1 12.4 18 5.5 5.3 2.5 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Laminin_G_3 PF13385.6 EKX31779.1 - 2.1e-16 60.4 0.0 4.3e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF1517 PF07466.11 EKX31780.1 - 1.9e-33 116.2 11.4 1.9e-30 106.4 4.3 3.1 2 1 0 2 2 2 2 Protein of unknown function (DUF1517) DUF4746 PF15928.5 EKX31780.1 - 6.1 6.2 12.5 7.7 5.8 12.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TT_ORF2 PF02957.15 EKX31780.1 - 6.7 7.7 8.4 17 6.4 8.4 1.6 1 0 0 1 1 1 0 TT viral ORF2 CitMHS PF03600.16 EKX31781.1 - 7.3e-22 77.9 33.9 2.2e-12 46.8 22.8 2.7 1 1 1 2 2 2 2 Citrate transporter SNAD1 PF18744.1 EKX31781.1 - 0.15 11.9 0.6 0.31 10.9 0.6 1.4 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 1 zf-MYND PF01753.18 EKX31782.1 - 0.00037 20.5 0.3 0.00037 20.5 0.3 2.0 2 1 0 2 2 2 1 MYND finger Zn_clus PF00172.18 EKX31784.1 - 2.2e-06 27.7 12.0 3.6e-06 27.0 12.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_binding_1 PF01035.20 EKX31784.1 - 0.014 15.5 0.1 0.02 15.0 0.1 1.3 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_16 PF10294.9 EKX31785.1 - 1.8e-20 73.4 0.0 2.7e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EKX31785.1 - 1.4e-05 24.7 0.0 2.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 EKX31785.1 - 2.3e-05 24.2 0.0 3.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 EKX31785.1 - 4.7e-05 24.0 0.0 0.00011 22.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EKX31785.1 - 0.00014 21.3 0.0 0.00021 20.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EKX31785.1 - 0.00058 19.7 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 EKX31785.1 - 0.0044 16.1 0.0 0.0063 15.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_15 PF09445.10 EKX31785.1 - 0.013 15.0 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 EKX31785.1 - 0.038 14.6 0.1 0.12 13.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.18 EKX31785.1 - 0.093 12.6 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cons_hypoth95 PF03602.15 EKX31785.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 EKX31785.1 - 0.16 12.7 0.0 0.44 11.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain 2OG-FeII_Oxy_3 PF13640.6 EKX31786.1 - 1.2e-15 58.1 0.0 2.1e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 EKX31786.1 - 7.8e-07 29.7 0.0 1.5e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 EKX31786.1 - 0.0078 16.6 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase TPR_19 PF14559.6 EKX31788.1 - 0.00084 19.8 0.0 0.0034 17.8 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX31788.1 - 0.0065 16.5 0.1 0.18 12.0 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX31788.1 - 0.17 11.8 0.4 2.7 8.0 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2723 PF11028.8 EKX31789.1 - 1.5e-26 93.4 4.5 3.2e-26 92.2 4.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2723) Ras PF00071.22 EKX31790.1 - 4.4e-57 192.2 0.0 5e-57 192.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EKX31790.1 - 2.7e-23 82.5 0.0 3.8e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EKX31790.1 - 1.5e-10 40.8 0.0 1.8e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EKX31790.1 - 1.5e-06 27.9 0.0 3.9e-06 26.5 0.0 1.5 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Lipase_GDSL_3 PF14606.6 EKX31790.1 - 0.07 13.3 0.0 0.094 12.8 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family SNF2_N PF00176.23 EKX31790.1 - 0.12 11.1 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Gtr1_RagA PF04670.12 EKX31790.1 - 0.16 11.3 0.0 0.22 10.9 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Mto2_bdg PF12808.7 EKX31791.1 - 0.085 13.2 2.8 0.15 12.4 2.8 1.3 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF3536 PF12055.8 EKX31792.1 - 0.011 15.1 0.1 0.022 14.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3536) HATPase_c PF02518.26 EKX31793.1 - 1.3e-24 86.8 0.0 3.1e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EKX31793.1 - 2.1e-21 76.2 0.3 4.1e-21 75.3 0.3 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Bac_rhodopsin PF01036.18 EKX31793.1 - 2.1e-14 53.7 13.1 2.1e-14 53.7 13.1 1.8 1 1 1 2 2 2 1 Bacteriorhodopsin-like protein HisKA PF00512.25 EKX31793.1 - 2e-13 50.2 0.4 4.8e-13 48.9 0.4 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 EKX31793.1 - 0.0069 16.3 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain IDO PF01231.18 EKX31794.1 - 2e-34 119.1 0.0 2.8e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase UCR_hinge PF02320.16 EKX31795.1 - 5e-24 84.3 4.2 5.9e-24 84.1 4.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein DegS PF05384.11 EKX31795.1 - 0.19 11.2 0.0 0.22 11.0 0.0 1.0 1 0 0 1 1 1 0 Sensor protein DegS Toxin_38 PF14866.6 EKX31795.1 - 1.6 9.0 11.2 0.31 11.4 1.4 2.5 2 2 0 2 2 2 0 Potassium channel toxin NT-C2 PF10358.9 EKX31796.1 - 0.094 12.4 0.3 0.25 11.0 0.1 2.1 2 1 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins WD40 PF00400.32 EKX31797.1 - 7.2e-11 42.5 10.4 0.0093 16.8 0.3 6.8 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX31797.1 - 3.3e-06 27.3 0.0 0.33 11.3 0.1 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EKX31797.1 - 0.32 11.5 1.5 1.3 9.6 0.1 2.8 4 0 0 4 4 4 0 PQQ-like domain Ribosomal_L34 PF00468.17 EKX31799.1 - 5.1e-09 36.0 3.8 1.1e-08 34.8 3.8 1.6 1 0 0 1 1 1 1 Ribosomal protein L34 FTR1 PF03239.14 EKX31800.1 - 3.1e-27 95.6 13.7 4.5e-15 55.6 0.6 2.3 1 1 0 2 2 2 2 Iron permease FTR1 family Phage_holin_3_6 PF07332.11 EKX31800.1 - 0.15 12.1 12.7 0.29 11.2 1.3 2.7 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III YqhR PF11085.8 EKX31800.1 - 0.69 9.8 9.5 0.57 10.1 1.1 2.3 2 0 0 2 2 2 0 Conserved membrane protein YqhR PDR_assoc PF08370.11 EKX31800.1 - 1.2 9.0 5.9 0.43 10.3 2.1 2.3 2 0 0 2 2 2 0 Plant PDR ABC transporter associated Fe_hyd_lg_C PF02906.14 EKX31801.1 - 5.2e-64 216.2 0.1 8.2e-64 215.6 0.1 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain DUF3446 PF11928.8 EKX31801.1 - 0.0021 18.3 11.4 0.0085 16.4 11.4 2.0 1 0 0 1 1 1 1 Early growth response N-terminal domain Fe_hyd_SSU PF02256.17 EKX31801.1 - 0.011 15.7 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Iron hydrogenase small subunit Herpes_pp85 PF04637.12 EKX31801.1 - 0.018 13.5 0.7 0.026 13.0 0.7 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) SR-25 PF10500.9 EKX31801.1 - 0.043 13.4 8.3 0.069 12.7 8.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Transposase_24 PF03004.14 EKX31801.1 - 0.17 12.0 0.2 0.41 10.7 0.2 1.6 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) DUF755 PF05501.11 EKX31801.1 - 0.76 10.1 10.9 1.4 9.2 10.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Ank_4 PF13637.6 EKX31803.1 - 4.3e-13 49.5 0.0 4.7e-13 49.4 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX31803.1 - 2.2e-11 43.8 0.1 4.2e-06 26.9 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX31803.1 - 6.9e-11 42.6 0.0 8.5e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX31803.1 - 4.5e-09 36.3 0.0 0.0025 18.2 0.0 2.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EKX31803.1 - 9.1e-08 31.8 0.1 0.0039 17.6 0.0 2.0 2 0 0 2 2 2 2 Ankyrin repeat ABC_membrane PF00664.23 EKX31804.1 - 9.4e-109 363.3 17.1 8.1e-63 212.6 2.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EKX31804.1 - 8.8e-65 217.4 0.1 1.7e-32 112.8 0.0 3.5 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EKX31804.1 - 5.7e-13 48.8 8.4 6.2e-05 22.5 0.0 4.2 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EKX31804.1 - 1.4e-08 35.1 0.1 0.014 15.7 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EKX31804.1 - 2.3e-07 30.5 1.5 0.022 14.5 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EKX31804.1 - 3e-07 31.0 3.1 0.0056 17.1 0.2 3.6 3 1 0 3 3 3 2 AAA ATPase domain Zeta_toxin PF06414.12 EKX31804.1 - 1.2e-06 28.0 0.1 0.036 13.3 0.0 3.1 3 0 0 3 3 3 2 Zeta toxin RsgA_GTPase PF03193.16 EKX31804.1 - 1.3e-06 28.4 0.0 0.067 13.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 EKX31804.1 - 6.6e-06 26.1 0.1 0.027 14.2 0.1 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 EKX31804.1 - 7e-06 25.9 1.0 0.15 11.8 0.1 3.3 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 EKX31804.1 - 7.8e-06 24.9 2.6 0.009 14.8 1.1 3.3 2 2 1 3 3 3 2 Predicted ATPase of the ABC class AAA_21 PF13304.6 EKX31804.1 - 8.7e-06 25.7 0.0 0.063 13.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EKX31804.1 - 3.3e-05 24.3 0.2 0.42 11.0 0.0 3.5 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EKX31804.1 - 0.00012 21.6 0.0 0.16 11.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF87 PF01935.17 EKX31804.1 - 0.00018 21.7 0.2 0.74 9.9 0.0 2.7 3 0 0 3 3 2 2 Helicase HerA, central domain AAA_25 PF13481.6 EKX31804.1 - 0.00021 20.9 0.0 0.85 9.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EKX31804.1 - 0.00034 20.6 0.2 0.21 11.6 0.0 3.8 3 2 0 3 3 3 1 AAA domain (dynein-related subfamily) G-alpha PF00503.20 EKX31804.1 - 0.0023 17.1 0.0 1.4 8.0 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit DUF815 PF05673.13 EKX31804.1 - 0.0035 16.5 0.1 2.3 7.3 0.0 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF815) ATP-synt_ab PF00006.25 EKX31804.1 - 0.007 16.0 0.2 1.7 8.3 0.0 2.8 3 0 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 EKX31804.1 - 0.013 16.1 0.0 2.1 8.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EKX31804.1 - 0.014 15.1 0.0 4.9 6.8 0.0 2.6 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EKX31804.1 - 0.017 15.2 0.0 2.9 8.0 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 EKX31804.1 - 0.024 14.8 0.0 1.6 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EKX31804.1 - 0.039 14.2 6.0 6.8 7.0 0.5 4.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit APS_kinase PF01583.20 EKX31804.1 - 0.041 13.8 0.1 3.8 7.4 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_28 PF13521.6 EKX31804.1 - 0.045 14.0 0.0 12 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EKX31804.1 - 0.05 14.0 0.1 19 5.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF2520 PF10728.9 EKX31804.1 - 0.06 13.1 0.1 15 5.3 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2520) FtsK_SpoIIIE PF01580.18 EKX31804.1 - 0.061 12.7 0.3 1.9 7.8 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 EKX31804.1 - 0.07 12.9 0.1 24 4.6 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 EKX31804.1 - 0.075 13.5 2.4 5.2 7.5 0.3 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EKX31804.1 - 0.097 13.0 2.9 12 6.2 0.0 3.1 3 1 0 3 3 2 0 AAA domain Arm PF00514.23 EKX31807.1 - 4.6e-14 51.9 0.7 0.0011 18.9 0.0 4.3 4 0 0 4 4 4 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EKX31807.1 - 0.0002 21.3 2.9 11 6.6 0.0 4.1 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.6 EKX31807.1 - 0.00023 21.6 9.0 0.0029 18.1 2.3 2.8 2 1 0 2 2 2 2 HEAT-like repeat HEAT_2 PF13646.6 EKX31807.1 - 0.0025 18.1 6.6 0.033 14.6 1.8 2.8 1 1 0 2 2 2 1 HEAT repeats DUF4630 PF15443.6 EKX31807.1 - 0.011 15.9 19.4 1.8 8.7 1.8 4.0 2 2 2 4 4 4 0 Domain of unknown function (DUF4630) Htr2 PF17909.1 EKX31807.1 - 0.33 11.2 15.8 0.57 10.5 0.9 4.1 2 2 2 4 4 4 0 Htr2 transmembrane domain E3_UbLigase_RBR PF18091.1 EKX31807.1 - 0.38 10.9 1.2 30 4.8 0.1 3.3 2 1 1 3 3 3 0 E3 Ubiquitin Ligase RBR C-terminal domain Creatininase PF02633.14 EKX31807.1 - 2 7.8 14.0 1.8 7.9 2.8 3.1 1 1 0 2 2 2 0 Creatinine amidohydrolase SRF-TF PF00319.18 EKX31808.1 - 9.5e-23 79.4 0.1 1.1e-22 79.2 0.1 1.1 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) GHD PF17834.1 EKX31808.1 - 0.049 13.7 0.0 0.063 13.3 0.0 1.1 1 0 0 1 1 1 0 Beta-sandwich domain in beta galactosidase Ank_2 PF12796.7 EKX31809.1 - 5.9e-25 87.7 5.7 8.4e-08 32.7 0.0 3.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX31809.1 - 3.1e-23 81.8 8.0 1.5e-07 31.8 0.1 4.2 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EKX31809.1 - 7.6e-12 45.1 0.8 8.3e-06 26.0 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 EKX31809.1 - 1.6e-11 43.3 0.2 0.022 15.3 0.0 4.8 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EKX31809.1 - 1.1e-07 31.9 6.8 0.081 13.3 0.1 4.6 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Zn_clus PF00172.18 EKX31810.1 - 4.9e-05 23.3 9.1 4.9e-05 23.3 9.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain His_Phos_1 PF00300.22 EKX31811.1 - 2.1e-38 132.0 0.0 5.7e-30 104.5 0.0 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) RRM_1 PF00076.22 EKX31812.1 - 1.8e-19 69.3 0.0 1.3e-08 34.6 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EKX31812.1 - 0.002 18.2 0.0 0.011 15.7 0.0 2.0 2 0 0 2 2 2 1 RNA binding motif RRM_7 PF16367.5 EKX31812.1 - 0.07 13.3 0.0 1.8 8.8 0.0 2.6 2 1 0 2 2 2 0 RNA recognition motif Nup35_RRM_2 PF14605.6 EKX31812.1 - 0.18 11.8 0.0 5.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif T3SSipB PF16535.5 EKX31813.1 - 0.32 11.5 10.2 1.1 9.7 10.2 1.9 1 0 0 1 1 1 0 Type III cell invasion protein SipB Red1 PF07964.11 EKX31813.1 - 4.5 5.4 16.1 7.3 4.7 16.1 1.3 1 0 0 1 1 1 0 Rec10 / Red1 Troponin PF00992.20 EKX31815.1 - 0.16 12.3 2.0 3.5 7.9 0.2 2.1 1 1 1 2 2 2 0 Troponin CK_II_beta PF01214.18 EKX31816.1 - 0.051 13.4 0.7 0.093 12.5 0.7 1.3 1 0 0 1 1 1 0 Casein kinase II regulatory subunit DUF1043 PF06295.12 EKX31817.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF4483 PF14825.6 EKX31818.1 - 0.0068 16.2 0.0 5.1 6.8 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4483) DUF1580 PF07618.11 EKX31818.1 - 0.078 12.6 3.9 44 3.8 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1580) SNF2_N PF00176.23 EKX31821.1 - 1.8e-56 191.4 0.9 6.5e-48 163.2 0.0 3.1 3 1 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX31821.1 - 4.8e-20 72.0 0.0 1.7e-19 70.2 0.0 2.0 2 0 0 2 2 1 1 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 EKX31821.1 - 0.0014 18.4 0.0 0.0044 16.7 0.0 1.9 2 0 0 2 2 2 1 SWI2/SNF2 ATPase zf-RING_UBOX PF13445.6 EKX31821.1 - 0.0022 18.0 2.4 0.0022 18.0 2.4 2.7 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EKX31821.1 - 0.0024 18.2 1.6 0.0024 18.2 1.6 3.9 4 0 0 4 4 4 1 Ring finger domain ResIII PF04851.15 EKX31821.1 - 0.0053 16.8 0.5 0.33 10.9 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CCDC53 PF10152.9 EKX31821.1 - 0.051 14.0 3.0 0.67 10.4 1.8 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Methyltransf_12 PF08242.12 EKX31821.1 - 0.07 13.9 0.3 25 5.7 0.0 3.4 3 0 0 3 3 3 0 Methyltransferase domain SAGA-Tad1 PF12767.7 EKX31821.1 - 0.085 12.6 5.0 0.24 11.1 0.5 2.5 3 0 0 3 3 3 0 Transcriptional regulator of RNA polII, SAGA, subunit MID_MedPIWI PF18296.1 EKX31821.1 - 0.095 12.5 7.1 0.014 15.2 2.3 1.9 2 0 0 2 2 2 0 MID domain of medPIWI BNR_3 PF13859.6 EKX31821.1 - 0.18 11.1 0.1 0.38 10.0 0.1 1.5 1 0 0 1 1 1 0 BNR repeat-like domain RNA_pol_Rbc25 PF08292.12 EKX31821.1 - 0.4 10.9 2.4 3.1 8.0 0.3 2.7 2 1 0 2 2 2 0 RNA polymerase III subunit Rpc25 EST1 PF10374.9 EKX31821.1 - 0.42 11.2 5.5 0.083 13.5 1.4 1.9 2 0 0 2 2 1 0 Telomerase activating protein Est1 Eapp_C PF10238.9 EKX31821.1 - 0.6 10.2 7.4 0.49 10.5 1.5 2.8 3 0 0 3 3 3 0 E2F-associated phosphoprotein Pex14_N PF04695.13 EKX31821.1 - 2.7 8.7 15.6 0.18 12.5 7.4 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 EKX31821.1 - 4.9 7.0 16.8 0.24 11.3 8.3 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ribosomal_S13 PF00416.22 EKX31822.1 - 6.5e-45 152.7 1.1 8.4e-45 152.3 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 H2TH PF06831.14 EKX31822.1 - 0.039 13.9 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase H2TH domain Ferlin_C PF16165.5 EKX31823.1 - 0.079 12.9 1.2 0.085 12.8 1.2 1.0 1 0 0 1 1 1 0 Ferlin C-terminus TIMELESS PF04821.14 EKX31824.1 - 3.8e-39 134.6 6.0 7.7e-36 123.8 0.7 3.1 3 0 0 3 3 3 2 Timeless protein TIMELESS_C PF05029.13 EKX31824.1 - 1.7e-13 50.6 0.4 1.7e-13 50.6 0.4 5.2 3 1 3 6 6 6 1 Timeless protein C terminal region Myb_DNA-binding PF00249.31 EKX31824.1 - 8.6e-06 25.9 0.0 3.6e-05 23.9 0.0 2.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX31824.1 - 0.099 12.9 1.0 0.35 11.2 0.1 2.6 2 0 0 2 2 2 0 Myb-like DNA-binding domain PNPase_C PF12111.8 EKX31825.1 - 7.4e-07 28.5 8.5 36 3.9 0.0 6.9 7 0 0 7 7 7 0 Polyribonucleotide phosphorylase C terminal Glyco_hydro_81 PF03639.13 EKX31825.1 - 0.00015 21.1 21.0 0.39 9.8 1.2 4.0 1 1 5 6 6 6 6 Glycosyl hydrolase family 81 N-terminal domain TEX12 PF15219.6 EKX31825.1 - 0.0022 18.3 1.5 8.2 6.8 0.1 3.1 1 1 4 5 5 5 5 Testis-expressed 12 Cas_GSU0054 PF09609.10 EKX31825.1 - 0.27 9.9 2.5 4.4 5.9 0.3 1.8 1 1 1 2 2 2 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) MOZART1 PF12554.8 EKX31825.1 - 0.85 9.5 18.1 1.3e+02 2.4 0.1 6.6 7 0 0 7 7 7 0 Mitotic-spindle organizing gamma-tubulin ring associated DUF5082 PF16888.5 EKX31825.1 - 2.2 8.6 10.7 4.7 7.5 4.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) BrnA_antitoxin PF14384.6 EKX31829.1 - 0.0072 16.8 0.2 0.11 13.0 0.0 2.4 2 0 0 2 2 2 1 BrnA antitoxin of type II toxin-antitoxin system DUF563 PF04577.14 EKX31831.1 - 1.2e-09 38.6 0.0 1.9e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) MID_MedPIWI PF18296.1 EKX31833.1 - 0.12 12.2 0.3 0.17 11.6 0.3 1.2 1 0 0 1 1 1 0 MID domain of medPIWI AAA PF00004.29 EKX31834.1 - 3.9e-05 24.1 0.0 0.002 18.6 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EKX31834.1 - 6.3e-05 23.3 0.1 0.00073 19.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EKX31834.1 - 0.001 19.5 0.0 0.0044 17.4 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 EKX31834.1 - 0.086 11.9 0.0 0.22 10.6 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 EKX31834.1 - 0.15 12.1 0.0 5.7 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF563 PF04577.14 EKX31834.1 - 0.21 11.7 0.0 0.44 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF563) AAA_23 PF13476.6 EKX31834.1 - 1.6 9.2 12.7 21 5.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain Ank_2 PF12796.7 EKX31835.1 - 1.1e-17 64.4 0.0 1e-06 29.2 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX31835.1 - 4e-17 60.6 0.0 0.0011 19.3 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 EKX31835.1 - 3.6e-14 52.5 0.0 0.00027 21.3 0.0 5.4 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 EKX31835.1 - 2.3e-11 44.0 0.6 0.00024 21.6 0.1 4.1 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX31835.1 - 4.8e-09 36.3 0.1 0.17 12.3 0.0 4.7 3 1 0 4 4 4 2 Ankyrin repeats (many copies) Isochorismatase PF00857.20 EKX31835.1 - 4.5e-06 26.9 0.4 1e-05 25.8 0.4 1.7 1 1 0 1 1 1 1 Isochorismatase family Ion_trans PF00520.31 EKX31835.1 - 9e-05 21.8 18.9 0.00015 21.1 18.9 1.3 1 0 0 1 1 1 1 Ion transport protein Pox_Ag35 PF03286.14 EKX31835.1 - 0.22 11.3 7.1 0.039 13.7 2.1 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Spt20 PF12090.8 EKX31835.1 - 7.2 6.2 11.3 14 5.2 11.3 1.4 1 0 0 1 1 1 0 Spt20 family Zn_clus PF00172.18 EKX31836.1 - 3e-05 24.0 15.4 3e-05 24.0 15.4 2.4 1 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAT PF15915.5 EKX31836.1 - 0.096 12.6 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 GAF and HTH_10 associated domain Glyco_transf_49 PF13896.6 EKX31837.1 - 5.8e-23 81.7 0.5 4.4e-08 32.9 0.2 3.2 3 0 0 3 3 3 3 Glycosyl-transferase for dystroglycan RNase_II_C_S1 PF18614.1 EKX31837.1 - 2.8 8.0 5.1 0.78 9.7 1.5 2.1 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain FmdA_AmdA PF03069.15 EKX31839.1 - 9.6e-25 87.2 0.0 5.2e-14 51.9 0.0 2.1 1 1 1 2 2 2 2 Acetamidase/Formamidase family BUD22 PF09073.10 EKX31840.1 - 6.6e-05 22.4 11.4 7.1e-05 22.3 11.4 1.1 1 0 0 1 1 1 1 BUD22 SID-1_RNA_chan PF13965.6 EKX31840.1 - 0.00014 20.4 11.3 0.00017 20.2 11.3 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 TRAP_alpha PF03896.16 EKX31840.1 - 0.00056 19.2 16.2 0.00056 19.2 16.2 1.4 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF4834 PF16118.5 EKX31840.1 - 0.00078 20.4 0.4 0.00078 20.4 0.4 2.4 2 1 1 3 3 2 1 Domain of unknown function (DUF4834) Nop14 PF04147.12 EKX31840.1 - 0.0019 16.5 23.9 0.0023 16.3 23.9 1.1 1 0 0 1 1 1 1 Nop14-like family CBP_BcsG PF11658.8 EKX31840.1 - 0.0024 16.4 1.3 0.0026 16.2 1.3 1.1 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsG FHIPEP PF00771.20 EKX31840.1 - 0.0026 16.3 8.9 0.0031 16.1 8.9 1.1 1 0 0 1 1 1 1 FHIPEP family DNA_pol_phi PF04931.13 EKX31840.1 - 0.0041 15.3 29.2 0.0051 15.0 29.2 1.2 1 0 0 1 1 1 1 DNA polymerase phi Astro_capsid_p PF12226.8 EKX31840.1 - 0.0089 15.2 21.8 0.013 14.7 21.8 1.2 1 0 0 1 1 1 1 Turkey astrovirus capsid protein Zip PF02535.22 EKX31840.1 - 0.0094 15.2 3.5 0.011 15.0 3.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2457 PF10446.9 EKX31840.1 - 0.01 15.0 28.1 0.013 14.7 28.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) YL1 PF05764.13 EKX31840.1 - 0.013 15.6 20.7 0.019 15.1 20.7 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DUF5313 PF17240.2 EKX31840.1 - 0.014 15.8 7.4 0.026 15.0 7.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5313) CobT PF06213.12 EKX31840.1 - 0.027 13.9 22.4 0.036 13.5 22.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF5523 PF17661.1 EKX31840.1 - 0.036 13.8 15.2 0.041 13.6 15.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) PHO4 PF01384.20 EKX31840.1 - 0.037 13.1 0.0 0.037 13.1 0.0 1.1 1 0 0 1 1 1 0 Phosphate transporter family V_ATPase_I PF01496.19 EKX31840.1 - 0.062 11.2 16.7 0.069 11.1 16.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SARAF PF06682.12 EKX31840.1 - 0.063 12.9 0.1 0.08 12.6 0.1 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CLN3 PF02487.17 EKX31840.1 - 0.069 12.2 8.8 0.088 11.8 8.4 1.4 1 1 0 1 1 1 0 CLN3 protein RRN3 PF05327.11 EKX31840.1 - 0.14 10.6 23.3 0.16 10.5 23.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CPSF100_C PF13299.6 EKX31840.1 - 0.15 12.3 5.5 0.23 11.6 5.5 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Pex24p PF06398.11 EKX31840.1 - 0.15 11.0 1.4 0.2 10.6 1.4 1.3 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Drc1-Sld2 PF11719.8 EKX31840.1 - 0.34 10.4 17.5 0.36 10.3 17.5 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein DUF913 PF06025.12 EKX31840.1 - 0.36 9.8 10.9 0.44 9.5 10.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Merozoite_SPAM PF07133.11 EKX31840.1 - 0.39 10.7 38.1 0.5 10.3 38.1 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CDC45 PF02724.14 EKX31840.1 - 0.39 8.9 20.1 0.51 8.6 20.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Connexin PF00029.19 EKX31840.1 - 0.54 10.0 12.8 0.32 10.7 10.6 1.9 1 1 0 1 1 1 0 Connexin SDA1 PF05285.12 EKX31840.1 - 0.71 9.2 29.7 0.97 8.8 29.7 1.1 1 0 0 1 1 1 0 SDA1 Vfa1 PF08432.10 EKX31840.1 - 0.89 9.9 15.6 1.5 9.1 15.6 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop53 PF07767.11 EKX31840.1 - 1.4 8.2 22.4 1.9 7.8 22.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Paf1 PF03985.13 EKX31840.1 - 3 6.7 24.2 0.033 13.2 17.0 1.3 2 0 0 2 2 1 0 Paf1 CSRNP_N PF16019.5 EKX31840.1 - 4.2 7.2 10.6 5.5 6.8 10.6 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus DUF761 PF05553.11 EKX31841.1 - 0.0069 15.9 0.8 2.7 7.6 0.1 3.1 3 0 0 3 3 3 2 Cotton fibre expressed protein T2SSF PF00482.23 EKX31841.1 - 0.15 12.0 0.0 0.61 10.1 0.0 2.0 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Chalcone_2 PF16035.5 EKX31842.1 - 0.13 12.0 1.0 5.3 6.8 0.2 2.8 2 1 1 3 3 3 0 Chalcone isomerase like DUF5446 PF17522.2 EKX31842.1 - 0.47 10.7 2.9 0.42 10.8 0.4 2.2 3 0 0 3 3 3 0 Family of unknown function (DUF5446) Snf7 PF03357.21 EKX31843.1 - 1.8e-12 47.2 14.4 2.5e-12 46.7 14.4 1.1 1 0 0 1 1 1 1 Snf7 IL11 PF07400.11 EKX31843.1 - 0.021 14.5 1.8 0.021 14.5 1.8 2.0 1 1 1 2 2 2 0 Interleukin 11 Sod_Ni PF09055.11 EKX31843.1 - 0.046 14.3 2.2 0.093 13.3 2.2 1.5 1 0 0 1 1 1 0 Nickel-containing superoxide dismutase DUF2312 PF10073.9 EKX31843.1 - 0.15 11.7 5.1 2.4 7.8 0.5 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) TBP PF00352.21 EKX31845.1 - 5.3e-07 29.5 0.0 0.0018 18.2 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) Pox_MCEL PF03291.16 EKX31846.1 - 3.1e-22 79.1 9.3 4.3e-18 65.5 2.1 2.2 2 0 0 2 2 2 2 mRNA capping enzyme mRNA_cap_enzyme PF01331.19 EKX31846.1 - 1e-16 61.3 0.1 2.7e-16 60.0 0.1 1.8 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EKX31846.1 - 3.8e-06 27.5 2.3 4.7e-05 24.0 1.8 3.1 2 1 0 2 2 2 1 mRNA capping enzyme, C-terminal domain Methyltransf_31 PF13847.6 EKX31846.1 - 0.00013 21.8 0.1 0.2 11.4 0.0 3.0 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 EKX31846.1 - 0.0013 19.3 0.0 1.1 10.0 0.0 3.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX31846.1 - 0.0021 18.7 0.0 9.9 6.9 0.0 3.5 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 EKX31846.1 - 0.031 15.0 0.0 0.64 10.8 0.0 2.8 2 0 0 2 2 2 0 Methyltransferase domain CNDH2_C PF16858.5 EKX31847.1 - 1.8 8.4 9.9 2.3 8.0 9.9 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CDC45 PF02724.14 EKX31847.1 - 2.3 6.4 18.3 2.8 6.1 18.3 1.0 1 0 0 1 1 1 0 CDC45-like protein dUTPase PF00692.19 EKX31848.1 - 4.5e-35 120.1 0.0 5e-35 120.0 0.0 1.0 1 0 0 1 1 1 1 dUTPase Histone PF00125.24 EKX31849.1 - 0.0027 18.1 1.9 1 9.7 0.3 3.6 3 1 1 4 4 4 2 Core histone H2A/H2B/H3/H4 DUF4854 PF16146.5 EKX31849.1 - 0.17 12.2 1.7 1.2 9.5 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4854) RAMP PF04901.13 EKX31849.1 - 0.61 10.1 4.9 0.27 11.3 0.5 2.5 2 2 0 2 2 2 0 Receptor activity modifying family DUF4116 PF13475.6 EKX31850.1 - 8.9e-100 326.3 13.9 6.2e-14 51.5 0.0 8.5 4 3 6 10 10 10 10 Domain of unknown function (DUF4116) GH97_C PF14509.6 EKX31850.1 - 0.086 13.1 1.1 0.2 11.9 0.5 2.1 1 1 1 2 2 2 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation RecJ_OB PF17768.1 EKX31852.1 - 0.096 12.9 0.5 6.8 7.0 0.0 3.2 3 0 0 3 3 3 0 RecJ OB domain CaiF_GrlA PF07180.11 EKX31852.1 - 0.099 12.6 4.0 14 5.6 0.0 3.4 3 0 0 3 3 3 0 CaiF/GrlA transcriptional regulator Zeta_toxin PF06414.12 EKX31852.1 - 0.17 11.2 0.0 0.4 9.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Pyrophosphatase PF00719.19 EKX31852.1 - 1.3 8.8 6.3 0.12 12.2 0.7 2.1 3 1 0 3 3 3 0 Inorganic pyrophosphatase DsrC PF04358.13 EKX31854.1 - 0.0034 17.9 0.6 0.0063 17.0 0.5 1.5 1 1 1 2 2 2 1 DsrC like protein Fumble PF03630.14 EKX31856.1 - 3.3e-05 23.2 0.0 4.2e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Fumble DUF4215 PF13948.6 EKX31858.1 - 1.1e-06 28.9 1.1 1.1e-06 28.9 1.1 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF4215) RCC1 PF00415.18 EKX31860.1 - 2.4e-49 165.7 11.2 1.2e-13 51.4 0.2 5.0 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX31860.1 - 6.8e-25 86.3 17.9 3.1e-09 36.4 0.2 4.3 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 EKX31860.1 - 0.087 12.5 0.0 15 5.2 0.0 2.9 3 0 0 3 3 3 0 TUP1-like enhancer of split DUF4213 PF13938.6 EKX31860.1 - 0.51 10.6 3.4 31 4.9 0.1 3.6 3 1 1 4 4 4 0 Putative heavy-metal chelation APG6_N PF17675.1 EKX31861.1 - 0.91 10.1 7.4 1.2 9.7 7.4 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region V_ATPase_I PF01496.19 EKX31861.1 - 1 7.2 3.8 0.98 7.2 3.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TT_ORF1 PF02956.14 EKX31861.1 - 3.6 6.1 14.3 4.8 5.8 14.3 1.3 1 0 0 1 1 1 0 TT viral orf 1 OAR PF03826.17 EKX31862.1 - 0.056 13.3 0.3 0.091 12.6 0.3 1.4 1 0 0 1 1 1 0 OAR domain DUF641 PF04859.12 EKX31862.1 - 0.058 13.7 6.5 0.088 13.1 6.5 1.3 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Csm1_N PF18504.1 EKX31862.1 - 0.14 12.5 8.3 1.8 9.0 1.2 2.1 1 1 1 2 2 2 0 Csm1 N-terminal domain TMF_DNA_bd PF12329.8 EKX31862.1 - 0.68 10.0 13.4 0.97 9.5 13.4 1.3 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Prefoldin PF02996.17 EKX31862.1 - 0.78 9.7 9.3 2.2 8.2 3.7 2.0 1 1 1 2 2 2 0 Prefoldin subunit Atg14 PF10186.9 EKX31862.1 - 0.89 8.6 7.1 0.92 8.5 7.1 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OmpH PF03938.14 EKX31862.1 - 1.2 9.5 11.4 1.6 9.1 3.1 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DivIC PF04977.15 EKX31862.1 - 1.6 8.6 10.2 1.1 9.0 1.8 2.0 1 1 1 2 2 2 0 Septum formation initiator FAM76 PF16046.5 EKX31862.1 - 1.9 7.8 8.3 3 7.1 8.3 1.4 1 1 0 1 1 1 0 FAM76 protein GPS2_interact PF15784.5 EKX31862.1 - 3.2 8.3 14.5 7.7 7.0 6.4 2.1 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain XhlA PF10779.9 EKX31862.1 - 4.8 7.5 10.6 21 5.4 3.3 2.1 1 1 1 2 2 2 0 Haemolysin XhlA PKcGMP_CC PF16808.5 EKX31862.1 - 9.7 6.1 19.2 3.2 7.7 5.0 3.4 2 2 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Pkinase PF00069.25 EKX31863.1 - 5.1e-18 65.4 0.0 6.6e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX31863.1 - 6.8e-06 25.6 0.0 4.3e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX31863.1 - 0.00016 21.1 0.0 0.00027 20.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like SET PF00856.28 EKX31864.1 - 1.1e-11 45.4 0.0 4.5e-11 43.4 0.0 1.9 1 1 0 1 1 1 1 SET domain Tim17 PF02466.19 EKX31865.1 - 2.5e-05 24.6 0.1 0.0066 16.8 0.0 2.2 2 0 0 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family EF-hand_1 PF00036.32 EKX31866.1 - 4.6e-17 60.2 5.3 0.00024 20.4 0.2 4.0 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EKX31866.1 - 4e-16 57.5 2.9 0.00025 20.7 0.1 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 EKX31866.1 - 6.3e-16 58.6 3.5 1.6e-09 38.0 0.1 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX31866.1 - 6.3e-13 47.6 1.0 0.00082 18.8 0.3 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EKX31866.1 - 2.4e-12 46.5 2.6 0.0064 16.3 0.2 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 EKX31866.1 - 0.00014 22.1 0.1 0.077 13.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain Caleosin PF05042.13 EKX31866.1 - 0.00068 19.6 0.8 0.4 10.6 0.0 3.6 3 1 1 4 4 4 1 Caleosin related protein EF-hand_4 PF12763.7 EKX31866.1 - 0.0014 18.5 1.1 0.032 14.2 0.1 2.8 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand DUF5580 PF17743.1 EKX31866.1 - 0.027 13.0 0.0 0.053 12.1 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_11 PF08976.11 EKX31866.1 - 0.034 15.0 0.0 0.46 11.4 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain PHB_depo_C PF06850.11 EKX31866.1 - 0.037 13.5 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 PHB de-polymerase C-terminus PEPcase PF00311.17 EKX31868.1 - 1.5e-259 863.4 0.0 2e-259 863.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 EKX31868.1 - 1.9e-07 30.0 0.0 1e-06 27.6 0.0 2.2 2 1 0 2 2 2 1 Phosphoenolpyruvate carboxylase HMD PF03201.16 EKX31868.1 - 0.18 12.0 0.1 0.48 10.7 0.1 1.6 1 0 0 1 1 1 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase CMS1 PF14617.6 EKX31869.1 - 6.9e-11 42.0 1.3 8.4e-11 41.7 1.3 1.1 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 EKX31869.1 - 0.0033 17.2 0.1 0.0061 16.3 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Ion_trans PF00520.31 EKX31870.1 - 4.4e-28 98.2 22.4 6.5e-28 97.6 22.4 1.2 1 0 0 1 1 1 1 Ion transport protein PH PF00169.29 EKX31870.1 - 0.00012 22.5 0.1 0.00048 20.6 0.1 2.0 1 1 0 1 1 1 1 PH domain PKD_channel PF08016.12 EKX31870.1 - 0.0017 17.1 8.3 0.0017 17.1 8.3 2.2 1 1 1 2 2 2 2 Polycystin cation channel CLZ PF16526.5 EKX31870.1 - 0.099 13.0 7.2 0.18 12.2 5.8 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Streptin-Immun PF11083.8 EKX31870.1 - 0.29 11.6 1.8 2.3 8.7 0.1 2.8 3 0 0 3 3 3 0 Lantibiotic streptin immunity protein MDM31_MDM32 PF08118.11 EKX31871.1 - 0.019 13.7 0.1 0.021 13.5 0.1 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins DUF4407 PF14362.6 EKX31871.1 - 0.024 14.0 0.9 0.029 13.7 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CobT PF06213.12 EKX31871.1 - 0.036 13.4 8.3 0.044 13.2 8.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Folate_carrier PF01770.18 EKX31871.1 - 0.14 10.8 2.5 0.18 10.5 2.5 1.0 1 0 0 1 1 1 0 Reduced folate carrier Peptidase_S49_N PF08496.10 EKX31871.1 - 0.18 11.8 2.7 0.27 11.3 2.7 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Connexin PF00029.19 EKX31871.1 - 0.22 11.2 1.3 0.27 11.0 1.3 1.1 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 EKX31871.1 - 0.22 10.2 1.7 0.24 10.1 1.7 1.1 1 0 0 1 1 1 0 Presenilin NOA36 PF06524.12 EKX31871.1 - 0.24 10.7 3.8 0.27 10.5 3.8 1.1 1 0 0 1 1 1 0 NOA36 protein Paf1 PF03985.13 EKX31871.1 - 0.28 10.2 13.1 0.34 9.9 13.1 1.1 1 0 0 1 1 1 0 Paf1 DUF3464 PF11947.8 EKX31871.1 - 0.57 9.9 4.4 0.84 9.4 4.4 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DNA_pol_phi PF04931.13 EKX31871.1 - 0.82 7.7 9.7 1.1 7.3 9.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Phage_Gp23 PF10669.9 EKX31871.1 - 0.94 9.8 8.0 1.4 9.3 8.0 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Usp PF00582.26 EKX31871.1 - 1.4 9.4 5.6 2.4 8.6 5.6 1.3 1 0 0 1 1 1 0 Universal stress protein family Roughex PF06020.11 EKX31871.1 - 2.1 7.4 9.7 2.6 7.0 9.7 1.1 1 0 0 1 1 1 0 Drosophila roughex protein DUF1682 PF07946.14 EKX31871.1 - 2.1 7.5 8.6 2.5 7.2 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DnaB PF00772.21 EKX31872.1 - 0.046 13.8 0.1 0.21 11.7 0.0 2.1 2 1 0 2 2 2 0 DnaB-like helicase N terminal domain Baculo_PEP_C PF04513.12 EKX31872.1 - 0.052 13.6 0.0 0.089 12.8 0.0 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Baculo_PEP_C PF04513.12 EKX31873.1 - 1.1e-07 32.0 0.1 1.8e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 EKX31873.1 - 5.9e-05 23.0 0.5 0.00011 22.2 0.5 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Fib_alpha PF08702.10 EKX31873.1 - 7.2e-05 23.0 0.4 0.00014 22.1 0.4 1.4 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family LPP PF04728.13 EKX31873.1 - 0.00015 22.1 1.7 0.0011 19.3 0.4 2.5 2 0 0 2 2 2 1 Lipoprotein leucine-zipper DUF1664 PF07889.12 EKX31873.1 - 0.0017 18.4 0.9 0.0026 17.8 0.3 1.6 2 0 0 2 2 1 1 Protein of unknown function (DUF1664) ApoLp-III PF07464.11 EKX31873.1 - 0.0034 17.5 0.6 0.011 15.8 0.7 1.7 2 0 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) DUF16 PF01519.16 EKX31873.1 - 0.0058 17.1 0.6 0.016 15.7 0.6 1.7 1 0 0 1 1 1 1 Protein of unknown function DUF16 CdvA PF18822.1 EKX31873.1 - 0.0067 16.2 0.4 0.013 15.3 0.4 1.4 1 0 0 1 1 1 1 CdvA-like coiled-coil domain Spc7 PF08317.11 EKX31873.1 - 0.012 14.5 0.7 0.019 13.9 0.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Bacillus_HBL PF05791.11 EKX31873.1 - 0.013 15.3 0.5 0.024 14.5 0.5 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) ING PF12998.7 EKX31873.1 - 0.023 15.3 0.9 0.27 11.8 0.8 2.5 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF5082 PF16888.5 EKX31873.1 - 0.024 14.9 0.8 0.069 13.4 0.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Fez1 PF06818.15 EKX31873.1 - 0.025 15.1 0.4 0.051 14.0 0.4 1.4 1 0 0 1 1 1 0 Fez1 Kre28 PF17097.5 EKX31873.1 - 0.026 13.5 1.6 0.052 12.5 1.6 1.5 1 0 0 1 1 1 0 Spindle pole body component Filament PF00038.21 EKX31873.1 - 0.028 14.0 0.2 0.049 13.2 0.2 1.3 1 0 0 1 1 1 0 Intermediate filament protein UPF0449 PF15136.6 EKX31873.1 - 0.037 14.5 0.1 0.12 12.9 0.0 1.9 2 0 0 2 2 1 0 Uncharacterised protein family UPF0449 Fzo_mitofusin PF04799.13 EKX31873.1 - 0.049 13.2 0.6 0.09 12.3 0.6 1.4 1 0 0 1 1 1 0 fzo-like conserved region DUF4533 PF15047.6 EKX31873.1 - 0.051 13.1 0.1 0.49 9.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4533) YtxH PF12732.7 EKX31873.1 - 0.054 14.0 10.4 0.12 12.9 1.1 3.2 2 1 1 3 3 3 0 YtxH-like protein SKA2 PF16740.5 EKX31873.1 - 0.057 13.2 0.5 0.12 12.1 0.5 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Prefoldin_2 PF01920.20 EKX31873.1 - 0.067 13.2 1.4 0.13 12.2 0.6 1.8 1 1 1 2 2 2 0 Prefoldin subunit Phasin PF05597.11 EKX31873.1 - 0.087 12.8 1.2 0.17 11.9 1.2 1.4 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Alanine_zipper PF11839.8 EKX31873.1 - 0.098 13.0 0.2 0.26 11.7 0.1 1.7 2 0 0 2 2 1 0 Alanine-zipper, major outer membrane lipoprotein DUF1515 PF07439.11 EKX31873.1 - 0.1 12.7 0.6 0.19 11.8 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) FPP PF05911.11 EKX31873.1 - 0.12 10.5 2.6 0.18 10.0 2.6 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Tup_N PF08581.10 EKX31873.1 - 0.13 12.6 2.2 0.29 11.4 2.2 1.6 1 0 0 1 1 1 0 Tup N-terminal HIP1_clath_bdg PF16515.5 EKX31873.1 - 0.13 12.9 0.9 0.3 11.7 0.9 1.5 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4164 PF13747.6 EKX31873.1 - 0.17 12.2 1.5 0.45 10.8 1.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Syntaxin-6_N PF09177.11 EKX31873.1 - 0.24 12.0 2.1 0.3 11.7 0.5 1.9 2 0 0 2 2 1 0 Syntaxin 6, N-terminal HALZ PF02183.18 EKX31873.1 - 0.46 10.8 2.8 1.6 9.0 0.6 2.9 2 1 1 3 3 2 0 Homeobox associated leucine zipper NPV_P10 PF05531.12 EKX31873.1 - 0.47 10.9 3.8 3.2 8.3 3.8 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 EKX31873.1 - 0.99 9.9 3.5 1.3 9.5 0.9 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF2205 PF10224.9 EKX31873.1 - 1.3 9.1 5.7 0.15 12.1 1.3 1.7 2 0 0 2 2 1 0 Short coiled-coil protein Ion_trans PF00520.31 EKX31874.1 - 6.8e-14 51.7 6.7 9.7e-14 51.2 6.7 1.2 1 0 0 1 1 1 1 Ion transport protein PH PF00169.29 EKX31874.1 - 6.4e-05 23.4 0.1 0.00022 21.7 0.1 2.0 1 1 0 1 1 1 1 PH domain CLZ PF16526.5 EKX31874.1 - 0.0052 17.1 5.8 0.016 15.5 5.8 1.9 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF724 PF05266.14 EKX31874.1 - 0.51 10.1 13.0 1.4 8.7 13.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF1126 PF06565.12 EKX31875.1 - 6.5e-90 295.9 0.0 1e-30 105.7 0.0 3.2 3 0 0 3 3 3 3 DUF1126 PH-like domain EphA2_TM PF14575.6 EKX31877.1 - 0.0013 19.5 2.9 0.0014 19.5 2.9 1.3 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF2207 PF09972.9 EKX31877.1 - 0.014 14.2 3.4 0.014 14.2 3.4 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 EKX31877.1 - 0.02 14.8 14.9 0.023 14.6 14.9 1.3 1 0 0 1 1 1 0 TMEM154 protein family PspB PF06667.12 EKX31877.1 - 0.021 14.9 1.7 0.028 14.5 1.7 1.2 1 0 0 1 1 1 0 Phage shock protein B Tetraspanin PF00335.20 EKX31877.1 - 0.038 13.7 1.1 0.04 13.6 1.1 1.1 1 0 0 1 1 1 0 Tetraspanin family TOC159_MAD PF11886.8 EKX31877.1 - 0.064 12.1 1.0 0.078 11.9 1.0 1.1 1 0 0 1 1 1 0 Translocase of chloroplast 159/132, membrane anchor domain Myc_target_1 PF15179.6 EKX31877.1 - 0.15 11.9 0.9 0.15 11.9 0.9 1.2 1 0 0 1 1 1 0 Myc target protein 1 DUF4834 PF16118.5 EKX31877.1 - 0.53 11.3 9.0 0.79 10.7 9.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Shisa PF13908.6 EKX31877.1 - 1.1 9.5 7.6 1.1 9.4 7.6 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Ly49 PF08391.10 EKX31877.1 - 1.9 8.9 10.4 2.3 8.6 10.4 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region ASFV_J13L PF05568.11 EKX31877.1 - 8.4 6.1 15.5 16 5.2 15.5 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein Pkinase PF00069.25 EKX31878.1 - 2.8e-48 164.6 0.0 5e-48 163.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX31878.1 - 9.5e-36 123.4 0.0 1.5e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX31878.1 - 8.4e-05 22.0 0.0 0.025 13.9 0.0 2.7 2 1 1 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 EKX31878.1 - 0.0031 16.3 0.0 0.0065 15.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX31878.1 - 0.044 13.7 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EKX31881.1 - 0.16 11.2 0.1 2.5 7.3 0.0 2.3 2 1 1 3 3 3 0 Protein tyrosine kinase zf-RING_UBOX PF13445.6 EKX31881.1 - 1 9.5 4.9 1.1 9.4 0.8 2.8 2 0 0 2 2 2 0 RING-type zinc-finger Pkinase_Tyr PF07714.17 EKX31883.1 - 1.3e-10 41.0 0.0 1.7e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX31883.1 - 4.1e-06 26.4 0.0 5.3e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Ephrin_rec_like PF07699.13 EKX31885.1 - 2.8e-12 46.2 14.8 1.9e-10 40.3 4.4 5.7 3 2 2 5 5 5 2 Putative ephrin-receptor like Gpi1 PF05024.15 EKX31886.1 - 5.8e-52 176.5 6.8 5.8e-52 176.5 6.8 1.8 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) DoxD PF04173.13 EKX31886.1 - 0.06 13.2 4.2 0.071 13.0 2.8 1.8 2 0 0 2 2 2 0 TQO small subunit DoxD Guanylate_cyc PF00211.20 EKX31887.1 - 3.4e-30 105.0 0.1 4e-14 52.6 0.1 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain CstA_5TM PF13722.6 EKX31887.1 - 1.9 8.9 7.5 3.3 8.1 5.8 2.3 2 0 0 2 2 2 0 5TM C-terminal transporter carbon starvation CstA PDZ PF00595.24 EKX31888.1 - 0.00045 20.5 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX31888.1 - 0.00075 19.3 0.1 0.0017 18.2 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Jnk-SapK_ap_N PF09744.9 EKX31888.1 - 0.016 15.4 1.3 0.029 14.6 1.3 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 PRTP PF01366.18 EKX31888.1 - 0.074 11.1 0.0 0.11 10.5 0.0 1.2 1 1 0 1 1 1 0 Herpesvirus processing and transport protein PDZ_2 PF13180.6 EKX31888.1 - 0.094 13.0 0.0 0.31 11.4 0.0 1.8 1 1 0 2 2 2 0 PDZ domain Coq4 PF05019.13 EKX31888.1 - 0.13 11.6 0.1 0.18 11.1 0.1 1.1 1 0 0 1 1 1 0 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Nup88 PF10168.9 EKX31888.1 - 0.47 8.2 2.3 0.62 7.8 2.3 1.1 1 0 0 1 1 1 0 Nuclear pore component TolA_bind_tri PF16331.5 EKX31888.1 - 1.2 9.3 7.4 11 6.2 0.1 2.9 2 1 1 3 3 3 0 TolA binding protein trimerisation CBM_20 PF00686.19 EKX31889.1 - 6.1e-28 96.6 0.0 1.3e-10 41.0 0.0 3.5 3 1 0 3 3 3 3 Starch binding domain DSPc PF00782.20 EKX31889.1 - 6.8e-17 61.5 0.0 2.3e-16 59.8 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX31889.1 - 0.032 13.8 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase CDKN3 PF05706.12 EKX31889.1 - 0.078 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 EKX31889.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Asp_protease_2 PF13650.6 EKX31891.1 - 0.00023 21.7 0.0 0.88 10.2 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 EKX31891.1 - 0.00033 21.2 0.0 0.86 10.2 0.0 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Epimerase PF01370.21 EKX31892.1 - 6.8e-13 48.6 0.0 7.8e-12 45.2 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EKX31892.1 - 4.1e-12 46.4 0.0 5.5e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EKX31892.1 - 7.4e-08 32.2 0.0 1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EKX31892.1 - 3.9e-05 22.9 0.0 7.4e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EKX31892.1 - 0.00033 19.8 0.0 0.00046 19.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 EKX31892.1 - 0.00059 19.5 0.1 0.00091 18.8 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 EKX31892.1 - 0.0009 19.2 0.2 0.0016 18.4 0.2 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EKX31892.1 - 0.0015 18.0 0.2 0.0022 17.5 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.18 EKX31892.1 - 0.0029 17.5 0.3 0.0046 16.9 0.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 EKX31892.1 - 0.0075 16.0 0.3 0.011 15.4 0.3 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Sacchrp_dh_NADP PF03435.18 EKX31892.1 - 0.031 14.5 0.0 0.052 13.8 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 EKX31892.1 - 0.072 12.4 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CbiJ PF02571.14 EKX31892.1 - 0.11 12.0 0.1 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK HlyIII PF03006.20 EKX31893.1 - 1.2e-51 175.6 13.2 2.1e-43 148.6 9.8 2.1 2 0 0 2 2 2 2 Haemolysin-III related baeRF_family5 PF18846.1 EKX31893.1 - 0.029 14.6 0.3 0.075 13.2 0.0 1.7 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 5 FlaC_arch PF05377.11 EKX31893.1 - 0.092 13.2 1.2 0.28 11.6 0.4 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Apolipoprotein PF01442.18 EKX31893.1 - 0.15 11.9 4.8 0.27 11.1 2.8 2.0 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 EKX31893.1 - 0.16 12.0 0.9 1.4 9.0 0.2 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin-6_N PF09177.11 EKX31893.1 - 0.75 10.4 2.1 3.1 8.4 0.1 2.3 2 1 0 2 2 2 0 Syntaxin 6, N-terminal F-box-like_2 PF13013.6 EKX31894.1 - 0.025 14.5 1.1 0.053 13.5 1.1 1.4 1 0 0 1 1 1 0 F-box-like domain RAP-1 PF03085.15 EKX31894.1 - 0.058 13.1 0.2 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1689 PF07954.11 EKX31894.1 - 2.9 8.3 4.8 39 4.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) STI1 PF17830.1 EKX31896.1 - 2e-05 24.4 28.4 0.008 16.1 5.8 4.1 1 1 3 4 4 4 3 STI1 domain DnaI_N PF07319.11 EKX31896.1 - 0.0038 17.9 3.1 0.0056 17.3 3.1 1.3 1 0 0 1 1 1 1 Primosomal protein DnaI N-terminus GerD PF17898.1 EKX31896.1 - 0.0059 16.6 17.9 0.01 15.8 12.5 1.8 1 1 1 2 2 2 2 Spore germination GerD central core domain DUF445 PF04286.12 EKX31896.1 - 0.16 11.8 0.4 0.19 11.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) PSD4 PF07631.11 EKX31896.1 - 0.16 12.5 3.8 0.23 12.0 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1592) LAGLIDADG_WhiA PF14527.6 EKX31896.1 - 0.18 11.9 0.8 17 5.5 0.1 2.4 1 1 1 2 2 2 0 WhiA LAGLIDADG-like domain T3SS_needle_F PF09392.10 EKX31896.1 - 2.1 8.6 9.4 1.8 8.8 4.3 2.4 1 1 1 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF RSN1_TM PF13967.6 EKX31897.1 - 0.071 12.9 0.0 0.087 12.6 0.0 1.0 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport TPR_2 PF07719.17 EKX31898.1 - 6.8e-14 50.8 6.5 0.17 12.1 0.0 8.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 EKX31898.1 - 5.5e-13 48.1 1.7 0.023 14.5 0.0 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EKX31898.1 - 1.7e-12 47.7 22.3 3.8e-08 33.7 0.0 5.4 4 1 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX31898.1 - 3.5e-11 42.4 5.7 2.1 8.8 0.0 8.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX31898.1 - 1.7e-10 41.1 9.5 0.0012 19.1 0.1 6.8 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX31898.1 - 2.8e-10 39.7 0.3 0.37 10.5 0.0 6.1 2 1 3 5 5 5 2 TPR repeat TPR_17 PF13431.6 EKX31898.1 - 3.4e-08 33.3 0.0 0.66 10.5 0.0 6.4 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX31898.1 - 8.1e-08 32.5 34.6 0.009 16.8 0.1 10.7 8 3 5 13 13 12 4 Tetratricopeptide repeat TPR_9 PF13371.6 EKX31898.1 - 2.3e-05 24.5 9.4 2.7e-05 24.2 0.1 4.8 3 1 2 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX31898.1 - 2.4e-05 24.4 2.5 0.072 13.3 0.0 3.7 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EKX31898.1 - 6.2e-05 22.8 5.1 14 6.0 0.0 7.9 9 0 0 9 9 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX31898.1 - 0.00013 22.0 3.6 0.76 9.9 0.1 4.8 4 1 1 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 EKX31898.1 - 0.0013 18.6 6.2 0.15 12.0 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 EKX31898.1 - 0.12 11.5 6.5 0.36 10.0 0.1 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat IF4E PF01652.18 EKX31900.1 - 1.4e-25 89.9 0.0 1.7e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E AAA_11 PF13086.6 EKX31902.1 - 7.6e-05 22.6 0.0 7.6e-05 22.6 0.0 2.6 2 1 0 2 2 1 1 AAA domain AAA_25 PF13481.6 EKX31902.1 - 0.0016 18.1 0.0 0.0031 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EKX31902.1 - 0.0049 16.6 0.0 0.0049 16.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EKX31902.1 - 0.013 15.0 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 EKX31902.1 - 0.015 14.4 0.0 0.023 13.8 0.0 1.3 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.29 EKX31902.1 - 0.026 15.0 0.0 0.073 13.5 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EKX31902.1 - 0.1 12.3 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.6 EKX31902.1 - 0.15 12.4 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EKX31902.1 - 0.15 12.4 0.0 0.15 12.4 0.0 2.2 2 1 0 2 2 1 0 AAA ATPase domain ResIII PF04851.15 EKX31902.1 - 0.18 11.8 0.0 0.18 11.8 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Amino_oxidase PF01593.24 EKX31902.1 - 1.5 8.0 4.9 2 7.6 4.9 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase cNMP_binding PF00027.29 EKX31903.1 - 1.7e-41 140.2 0.1 2.1e-20 72.6 0.0 3.2 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Dpy-30 PF05186.13 EKX31903.1 - 2.5e-13 49.5 0.0 4.9e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Dpy-30 motif DUF4197 PF13852.6 EKX31903.1 - 0.063 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4197) YozE_SAM_like PF06855.12 EKX31903.1 - 0.078 13.2 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 YozE SAM-like fold CH PF00307.31 EKX31904.1 - 1.1e-07 32.0 0.0 1.2e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 EKX31904.1 - 0.0092 16.1 0.0 0.0097 16.0 0.0 1.1 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 EKX31904.1 - 0.048 13.5 0.0 0.053 13.4 0.0 1.1 1 0 0 1 1 1 0 CAMSAP CH domain Imm70 PF15601.6 EKX31904.1 - 0.078 12.5 0.0 0.081 12.5 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 70 Microtub_bind PF13931.6 EKX31905.1 - 3.5e-05 24.2 0.1 3.5e-05 24.2 0.1 5.5 2 1 3 6 6 4 1 Kinesin-associated microtubule-binding Collagen_mid PF15984.5 EKX31905.1 - 0.00044 20.0 7.2 0.00069 19.4 2.4 2.5 2 1 0 2 2 2 1 Bacterial collagen, middle region DUF4201 PF13870.6 EKX31905.1 - 0.0089 15.8 17.1 0.0089 15.8 17.1 4.8 1 1 2 4 4 3 1 Domain of unknown function (DUF4201) DUF1515 PF07439.11 EKX31905.1 - 0.0096 15.9 0.5 0.0096 15.9 0.5 4.8 2 2 2 5 5 5 2 Protein of unknown function (DUF1515) Filament PF00038.21 EKX31905.1 - 0.015 14.9 59.6 0.012 15.2 7.6 4.1 2 2 2 4 4 4 0 Intermediate filament protein Prominin PF05478.11 EKX31905.1 - 0.091 10.7 47.6 0.081 10.9 20.7 2.8 1 1 2 3 3 3 0 Prominin DAP_epimerase PF01678.19 EKX31905.1 - 0.11 12.6 0.1 0.39 10.9 0.1 1.9 1 0 0 1 1 1 0 Diaminopimelate epimerase DUF1664 PF07889.12 EKX31905.1 - 0.33 11.0 52.2 0.27 11.3 1.7 6.2 2 2 4 6 6 6 0 Protein of unknown function (DUF1664) Tape_meas_lam_C PF09718.10 EKX31905.1 - 0.52 10.5 14.5 0.13 12.4 0.8 5.3 3 1 3 6 6 6 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Baculo_PEP_C PF04513.12 EKX31905.1 - 1.1 9.3 37.0 26 4.9 3.9 5.5 1 1 4 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 EKX31905.1 - 1.8 7.3 59.5 0.2 10.5 8.7 4.2 1 1 2 3 3 2 0 Spc7 kinetochore protein Fez1 PF06818.15 EKX31905.1 - 3.5 8.0 64.2 0.58 10.6 16.7 4.3 1 1 3 4 4 3 0 Fez1 Sec8_exocyst PF04048.14 EKX31905.1 - 7.3 6.5 43.9 0.13 12.1 2.9 5.3 1 1 3 5 5 5 0 Sec8 exocyst complex component specific domain Kinesin PF00225.23 EKX31906.1 - 1.4e-111 372.7 0.1 1.6e-111 372.4 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX31906.1 - 8.2e-28 97.2 0.3 2.5e-27 95.6 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding PIF1 PF05970.14 EKX31906.1 - 0.019 14.2 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase APOBEC4 PF18775.1 EKX31906.1 - 0.12 12.5 0.0 20 5.4 0.0 2.3 2 0 0 2 2 2 0 APOBEC4 DUF87 PF01935.17 EKX31906.1 - 0.17 11.9 1.3 19 5.2 0.5 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain UPF0449 PF15136.6 EKX31906.1 - 0.41 11.1 2.2 1.7 9.2 0.1 2.6 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 Glyco_hydro_59M PF17387.2 EKX31907.1 - 0.09 12.9 0.1 0.13 12.4 0.1 1.3 1 1 0 1 1 1 0 Glycosyl hydrolase family 59 central domain MORN PF02493.20 EKX31908.1 - 5.7e-36 120.3 32.0 1.4e-06 27.8 0.7 8.0 8 0 0 8 8 8 6 MORN repeat Mannosyl_trans PF05007.13 EKX31909.1 - 9e-59 199.4 15.3 1.4e-58 198.8 15.3 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 EKX31909.1 - 1.2e-12 47.6 19.0 1.4e-12 47.4 19.0 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 EKX31909.1 - 6.6e-10 39.1 15.4 6.6e-10 39.1 15.4 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 87 PA14 PF07691.12 EKX31910.1 - 2.9e-19 69.3 1.0 3.8e-09 36.5 0.0 3.5 3 0 0 3 3 3 3 PA14 domain SRCR PF00530.18 EKX31910.1 - 4.1e-16 59.3 10.1 1.1e-15 57.9 10.1 1.8 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Lectin_C PF00059.21 EKX31910.1 - 6.3e-12 46.2 0.1 6.3e-12 46.2 0.1 2.7 3 0 0 3 3 3 1 Lectin C-type domain Collagen PF01391.18 EKX31910.1 - 2.9e-07 30.1 26.9 5.7e-07 29.2 26.9 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Crystall PF00030.19 EKX31910.1 - 3.8e-05 23.8 0.2 1.7 8.9 0.1 3.6 2 1 0 3 3 3 2 Beta/Gamma crystallin SRCR_2 PF15494.6 EKX31910.1 - 0.00011 22.6 6.8 0.00052 20.5 6.1 2.4 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain CE2_N PF17996.1 EKX31910.1 - 0.00014 21.8 0.0 1.1 9.3 0.0 3.6 3 0 0 3 3 3 2 Carbohydrate esterase 2 N-terminal Hepsin-SRCR PF09272.10 EKX31910.1 - 0.011 16.2 0.2 0.028 14.9 0.2 1.6 1 0 0 1 1 1 0 Hepsin, SRCR domain Crystall_3 PF08964.10 EKX31910.1 - 0.016 15.3 0.9 0.52 10.5 0.1 2.9 3 0 0 3 3 3 0 Beta/Gamma crystallin Surfac_D-trimer PF09006.11 EKX31910.1 - 0.061 13.2 0.3 0.13 12.1 0.3 1.5 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation Fascin PF06268.13 EKX31910.1 - 0.33 11.2 1.4 95 3.3 0.0 3.9 4 0 0 4 4 4 0 Fascin domain ANF_receptor PF01094.28 EKX31913.1 - 1.8e-69 234.5 8.7 6.8e-36 124.1 0.4 2.3 2 0 0 2 2 2 2 Receptor family ligand binding region Peripla_BP_6 PF13458.6 EKX31913.1 - 1.6e-15 57.6 4.0 2.2e-08 34.2 0.3 3.2 3 0 0 3 3 3 2 Periplasmic binding protein LysM PF01476.20 EKX31914.1 - 5.3e-10 39.2 0.1 4.7e-07 29.8 0.0 2.2 2 0 0 2 2 2 2 LysM domain Phage_tail_X PF05489.12 EKX31914.1 - 0.02 14.6 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X TMF_TATA_bd PF12325.8 EKX31915.1 - 0.0036 17.5 17.9 0.026 14.7 1.9 3.0 1 1 0 2 2 2 2 TATA element modulatory factor 1 TATA binding DUF1192 PF06698.11 EKX31915.1 - 0.013 15.5 1.8 0.013 15.5 1.8 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1192) RNase_PH PF01138.21 EKX31915.1 - 0.1 13.1 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 3' exoribonuclease family, domain 1 Haspin_kinase PF12330.8 EKX31915.1 - 0.24 10.3 6.6 0.35 9.7 6.6 1.2 1 0 0 1 1 1 0 Haspin like kinase domain bZIP_1 PF00170.21 EKX31915.1 - 5.9 7.1 12.9 0.14 12.3 0.4 3.5 2 1 2 4 4 4 0 bZIP transcription factor Ank_2 PF12796.7 EKX31916.1 - 3.7e-24 85.1 0.1 6.1e-16 58.8 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX31916.1 - 1.1e-19 70.5 0.1 1.2e-10 41.7 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX31916.1 - 2.6e-18 65.8 0.1 6.7e-10 39.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX31916.1 - 3.2e-16 57.8 0.0 1.2e-06 28.3 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EKX31916.1 - 3.5e-15 55.7 0.0 1.3e-06 28.6 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat NHL PF01436.21 EKX31917.1 - 1.3e-06 28.1 3.6 0.61 10.2 0.1 4.6 4 1 0 4 4 4 3 NHL repeat SGL PF08450.12 EKX31917.1 - 0.015 14.9 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Ephrin_rec_like PF07699.13 EKX31918.1 - 7.1e-42 140.9 87.1 2.3e-07 30.5 6.7 7.9 4 3 4 8 8 8 8 Putative ephrin-receptor like NCD3G PF07562.14 EKX31918.1 - 8e-14 51.3 63.6 8.1e-05 22.5 6.3 6.6 5 1 1 6 6 6 6 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX31918.1 - 4.5e-09 36.6 58.6 0.085 13.3 0.3 9.8 5 4 5 10 10 10 8 TNFR/NGFR cysteine-rich region Laminin_EGF PF00053.24 EKX31918.1 - 0.015 15.4 73.6 1.1 9.4 7.4 7.9 1 1 4 6 6 6 0 Laminin EGF domain EGF PF00008.27 EKX31918.1 - 0.024 15.0 24.8 4.2 7.8 0.3 6.7 5 0 0 5 5 5 0 EGF-like domain EGF_2 PF07974.13 EKX31918.1 - 0.17 12.2 30.9 1.3 9.4 0.0 6.7 6 1 0 6 6 6 0 EGF-like domain VSP PF03302.13 EKX31918.1 - 0.82 8.5 70.7 15 4.3 15.3 4.4 1 1 1 3 3 3 0 Giardia variant-specific surface protein SHIPPO-rpt PF07004.12 EKX31918.1 - 1 10.4 8.3 4.2e+02 2.1 0.0 6.3 6 0 0 6 6 6 0 Sperm-tail PG-rich repeat Ephrin_rec_like PF07699.13 EKX31919.1 - 3.5e-26 90.7 43.2 4.6e-09 35.9 4.1 4.1 3 1 1 4 4 4 4 Putative ephrin-receptor like NCD3G PF07562.14 EKX31919.1 - 2.6e-08 33.7 33.8 9.6e-05 22.3 7.2 3.9 3 2 0 3 3 3 3 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX31919.1 - 0.00016 22.0 26.2 0.042 14.3 0.4 5.4 2 2 2 5 5 5 5 TNFR/NGFR cysteine-rich region EGF_2 PF07974.13 EKX31919.1 - 0.0055 17.0 13.6 0.14 12.6 1.3 3.9 2 2 0 2 2 2 2 EGF-like domain Laminin_EGF PF00053.24 EKX31919.1 - 0.057 13.6 37.2 0.71 10.1 12.7 4.6 1 1 3 4 4 4 0 Laminin EGF domain EGF PF00008.27 EKX31919.1 - 0.71 10.2 19.0 0.16 12.3 1.8 3.9 4 1 0 4 4 4 0 EGF-like domain CUB PF00431.20 EKX31920.1 - 0.015 15.7 0.1 0.096 13.0 0.0 2.2 2 0 0 2 2 2 0 CUB domain PT PF04886.12 EKX31922.1 - 4.9e-07 29.2 7.4 1e-06 28.2 7.4 1.5 1 0 0 1 1 1 1 PT repeat Caskin1-CID PF16600.5 EKX31922.1 - 0.92 10.1 7.1 2.2 8.9 7.1 1.6 1 0 0 1 1 1 0 Caskin1 CASK-interaction domain DUF999 PF06198.11 EKX31923.1 - 0.072 13.1 1.1 58 3.7 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF999) MFS_1 PF07690.16 EKX31925.1 - 1.9e-09 36.9 3.6 1.9e-09 36.9 3.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EKX31925.1 - 0.001 18.1 0.5 0.0018 17.2 0.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 EKX31925.1 - 0.1 11.0 0.2 0.13 10.7 0.2 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) SNF2_N PF00176.23 EKX31926.1 - 7e-51 173.0 0.5 1.1e-50 172.3 0.5 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX31926.1 - 3.6e-20 72.4 0.0 2.3e-18 66.6 0.0 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX31926.1 - 6.2e-09 36.1 0.0 1.2e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EKX31926.1 - 4.9e-05 22.6 0.1 0.00013 21.2 0.1 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 EKX31926.1 - 0.00015 21.6 0.0 0.0004 20.2 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 EKX31926.1 - 0.0016 17.7 0.0 0.0035 16.6 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 EKX31926.1 - 0.0073 16.0 0.1 0.038 13.6 0.1 2.0 1 1 0 1 1 1 1 SWI2/SNF2 ATPase TniB PF05621.11 EKX31926.1 - 0.042 13.3 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein HscB_4_cys PF18256.1 EKX31927.1 - 0.0037 17.1 11.0 0.12 12.2 0.1 3.1 3 0 0 3 3 3 2 Co-chaperone HscB tetracysteine metal binding motif Cys_rich_CPXG PF14255.6 EKX31927.1 - 0.0041 17.0 1.0 1.9 8.4 0.1 2.4 2 0 0 2 2 2 2 Cysteine-rich CPXCG C1_2 PF03107.16 EKX31927.1 - 0.026 14.9 7.8 2.8 8.3 0.1 2.9 2 1 1 3 3 3 0 C1 domain HNH_5 PF14279.6 EKX31927.1 - 0.12 12.2 7.0 2 8.4 3.1 2.5 2 1 0 2 2 2 0 HNH endonuclease Ribosomal_S14 PF00253.21 EKX31927.1 - 0.15 11.8 0.9 21 5.0 0.0 2.6 3 0 0 3 3 3 0 Ribosomal protein S14p/S29e Rib_hydrolayse PF02267.17 EKX31927.1 - 0.71 9.2 3.1 1.4 8.3 0.5 2.0 2 0 0 2 2 2 0 ADP-ribosyl cyclase DUF2688 PF10892.8 EKX31927.1 - 0.73 9.3 4.4 18 4.9 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2688) zf-CCCH_6 PF18585.1 EKX31927.1 - 0.93 9.4 3.6 15 5.6 0.2 2.5 3 0 0 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Tnp_zf-ribbon_2 PF13842.6 EKX31927.1 - 2.8 8.8 9.5 18 6.3 0.1 3.2 3 0 0 3 3 3 0 DDE_Tnp_1-like zinc-ribbon PSI_integrin PF17205.3 EKX31927.1 - 3.2 7.6 10.5 2.7 7.8 0.1 2.5 2 1 0 2 2 2 0 Integrin plexin domain zf-RVT PF13966.6 EKX31927.1 - 4.2 8.1 7.1 51 4.7 0.3 3.0 2 1 1 3 3 3 0 zinc-binding in reverse transcriptase Rota_NS6 PF04866.12 EKX31928.1 - 0.28 11.4 1.2 8.3 6.7 0.1 2.8 2 1 0 2 2 2 0 Rotavirus non-structural protein 6 TMEM126 PF07114.11 EKX31929.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 126 Pkinase PF00069.25 EKX31931.1 - 6.5e-26 91.3 0.1 3.9e-13 49.4 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EKX31931.1 - 1.6e-12 47.3 0.2 1.3e-06 27.9 0.1 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EKX31931.1 - 0.022 14.1 0.0 0.47 9.7 0.0 2.0 1 1 1 2 2 2 0 Kinase-like Kdo PF06293.14 EKX31931.1 - 0.14 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_transf_41 PF13844.6 EKX31932.1 - 5.1e-55 186.8 2.4 7e-28 97.3 0.0 3.1 2 1 1 3 3 3 3 Glycosyl transferase family 41 TPR_1 PF00515.28 EKX31932.1 - 1.5e-19 68.9 4.9 4.5e-06 26.2 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 EKX31932.1 - 3.3e-16 58.0 4.5 0.0037 17.3 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX31932.1 - 8.9e-15 53.6 1.2 7.6e-05 22.6 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX31932.1 - 2.7e-14 52.5 0.4 0.00028 20.5 0.1 5.0 2 1 3 5 5 5 4 TPR repeat TPR_14 PF13428.6 EKX31932.1 - 1.1e-10 41.4 3.2 0.0062 17.3 0.0 5.5 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX31932.1 - 6.3e-10 38.8 2.4 0.025 14.9 0.3 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX31932.1 - 2.6e-09 37.6 0.2 0.00013 22.6 0.1 3.8 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX31932.1 - 2.1e-07 31.1 4.6 0.091 13.1 0.1 4.1 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX31932.1 - 3.8e-07 30.5 4.1 0.00022 21.7 0.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX31932.1 - 1.1e-06 28.2 0.3 0.021 14.8 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX31932.1 - 3.1e-05 24.1 2.8 0.021 15.1 0.9 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EKX31932.1 - 0.0002 21.1 5.9 1.3 8.9 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat FAT PF02259.23 EKX31932.1 - 0.0036 16.6 0.8 0.3 10.2 0.3 2.4 1 1 1 2 2 2 1 FAT domain DED PF01335.21 EKX31932.1 - 0.022 15.1 0.2 0.064 13.6 0.2 1.8 1 0 0 1 1 1 0 Death effector domain TPR_6 PF13174.6 EKX31932.1 - 0.067 13.9 0.6 69 4.4 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EKX31932.1 - 0.092 12.9 1.0 30 4.9 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 EKX31932.1 - 0.99 9.8 6.2 7.2 7.0 0.1 3.2 3 1 1 4 4 4 0 Bacterial transcriptional activator domain TPR_1 PF00515.28 EKX31933.1 - 3.6e-15 55.0 3.7 1.8e-05 24.3 0.1 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX31933.1 - 1.1e-10 40.8 4.7 4.1e-05 23.4 0.2 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX31933.1 - 6.7e-08 32.1 2.9 0.0027 17.8 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX31933.1 - 4.4e-06 26.7 3.9 0.00021 21.3 0.1 2.9 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 EKX31933.1 - 4.8e-06 26.8 6.1 0.0021 18.3 3.4 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX31933.1 - 9.4e-05 22.9 0.3 0.00062 20.2 0.3 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX31933.1 - 9.4e-05 22.6 2.9 0.00026 21.1 3.2 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EKX31933.1 - 0.00083 19.5 0.5 0.0025 17.9 0.1 1.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX31933.1 - 0.00085 19.9 0.5 0.045 14.6 0.1 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX31933.1 - 0.0022 17.9 3.3 1.1 9.4 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX31933.1 - 0.078 13.6 0.8 3.2 8.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EKX31933.1 - 0.079 13.6 0.1 0.98 10.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX31933.1 - 0.11 12.4 7.6 3.1 7.8 0.6 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EKX31933.1 - 0.15 11.7 2.7 4.8 7.0 0.0 2.8 2 1 1 3 3 3 0 TPR repeat MIT PF04212.18 EKX31933.1 - 0.87 9.7 5.1 4.9 7.3 0.4 2.8 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain Aldo_ket_red PF00248.21 EKX31934.1 - 8.7e-60 202.4 0.0 1e-59 202.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Bmt2 PF11968.8 EKX31935.1 - 0.02 14.7 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Keratin_2_head PF16208.5 EKX31935.1 - 0.091 12.9 18.8 0.15 12.2 18.8 1.2 1 0 0 1 1 1 0 Keratin type II head DUF5320 PF17253.2 EKX31935.1 - 0.16 13.1 7.9 0.4 11.8 7.9 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5320) GDP_Man_Dehyd PF16363.5 EKX31936.1 - 1.3e-74 251.6 0.0 1.5e-74 251.4 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EKX31936.1 - 3e-58 197.2 0.0 3.6e-58 196.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EKX31936.1 - 1.4e-21 76.9 0.0 5.4e-21 75.0 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EKX31936.1 - 5.4e-21 74.8 0.0 6.9e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EKX31936.1 - 2.8e-18 66.0 0.1 1.8e-17 63.4 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 EKX31936.1 - 9e-14 51.2 0.0 1.4e-13 50.6 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EKX31936.1 - 4.8e-05 23.3 0.0 7.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EKX31936.1 - 0.075 12.5 0.0 5.9 6.3 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase LysM PF01476.20 EKX31937.1 - 5.6e-08 32.7 0.0 0.014 15.4 0.0 3.0 2 0 0 2 2 2 2 LysM domain AAA_16 PF13191.6 EKX31938.1 - 3e-05 24.5 0.0 3e-05 24.5 0.0 2.8 3 0 0 3 3 1 1 AAA ATPase domain AAA_23 PF13476.6 EKX31938.1 - 6.9e-05 23.4 26.7 0.3 11.6 26.2 2.5 2 0 0 2 2 2 2 AAA domain TFIIA PF03153.13 EKX31938.1 - 0.00011 22.4 43.9 0.00018 21.7 43.9 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PIP5K PF01504.18 EKX31938.1 - 0.0005 19.4 9.2 0.00076 18.8 9.2 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase AAA_18 PF13238.6 EKX31938.1 - 0.00074 20.1 6.2 0.00084 19.9 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.14 EKX31938.1 - 0.00084 19.3 0.0 0.0032 17.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) DUF4045 PF13254.6 EKX31938.1 - 0.001 18.8 13.3 0.0021 17.8 13.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4045) AAA_11 PF13086.6 EKX31938.1 - 0.0013 18.6 22.6 0.33 10.7 0.1 2.3 2 0 0 2 2 2 2 AAA domain Neur_chan_memb PF02932.16 EKX31938.1 - 0.0014 18.8 8.2 0.0021 18.2 8.2 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region AAA_22 PF13401.6 EKX31938.1 - 0.0041 17.4 0.0 0.0041 17.4 0.0 2.4 2 1 0 2 2 1 1 AAA domain Exonuc_VII_L PF02601.15 EKX31938.1 - 0.0045 16.6 14.7 0.0061 16.2 14.7 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit DDHD PF02862.17 EKX31938.1 - 0.0056 16.9 15.5 0.011 15.9 15.5 1.4 1 0 0 1 1 1 1 DDHD domain Ploopntkinase3 PF18751.1 EKX31938.1 - 0.0056 16.6 0.0 0.0056 16.6 0.0 1.7 2 0 0 2 2 1 1 P-loop Nucleotide Kinase3 Hamartin PF04388.12 EKX31938.1 - 0.0078 14.9 13.2 0.011 14.4 13.2 1.2 1 0 0 1 1 1 1 Hamartin protein AAA_29 PF13555.6 EKX31938.1 - 0.0092 15.7 0.7 0.023 14.4 0.7 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EKX31938.1 - 0.0093 16.5 0.1 0.0093 16.5 0.1 2.5 2 0 0 2 2 1 1 ABC transporter Velvet PF11754.8 EKX31938.1 - 0.0096 15.9 14.9 0.019 14.9 14.9 1.4 1 0 0 1 1 1 1 Velvet factor CDC45 PF02724.14 EKX31938.1 - 0.014 13.7 14.2 0.021 13.2 14.2 1.2 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 EKX31938.1 - 0.017 15.0 19.6 0.028 14.3 19.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_33 PF13671.6 EKX31938.1 - 0.018 15.2 0.0 0.018 15.2 0.0 2.9 2 1 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 EKX31938.1 - 0.02 15.3 0.0 0.02 15.3 0.0 2.1 2 1 0 2 2 1 0 RNA helicase DUF913 PF06025.12 EKX31938.1 - 0.021 13.8 10.5 0.033 13.2 10.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) EPL1 PF10513.9 EKX31938.1 - 0.024 15.0 18.0 0.053 13.9 18.0 1.6 1 0 0 1 1 1 0 Enhancer of polycomb-like AAA_25 PF13481.6 EKX31938.1 - 0.025 14.2 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Tim54 PF11711.8 EKX31938.1 - 0.03 13.1 15.2 0.048 12.4 15.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Peptidase_S64 PF08192.11 EKX31938.1 - 0.045 12.2 14.8 0.067 11.7 14.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 SMC_N PF02463.19 EKX31938.1 - 0.05 13.0 0.0 0.05 13.0 0.0 2.5 3 0 0 3 3 2 0 RecF/RecN/SMC N terminal domain AAA PF00004.29 EKX31938.1 - 0.051 14.0 0.0 0.051 14.0 0.0 2.1 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) PAT1 PF09770.9 EKX31938.1 - 0.053 11.8 35.8 0.069 11.4 35.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 EKX31938.1 - 0.074 11.8 25.0 0.11 11.2 25.0 1.1 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 EKX31938.1 - 0.076 13.2 17.0 0.93 9.7 16.3 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal AAA_28 PF13521.6 EKX31938.1 - 0.081 13.2 0.0 0.081 13.2 0.0 2.9 2 1 0 2 2 1 0 AAA domain MMR_HSR1 PF01926.23 EKX31938.1 - 0.11 12.6 0.0 0.11 12.6 0.0 2.0 2 0 0 2 2 1 0 50S ribosome-binding GTPase eIF-3_zeta PF05091.12 EKX31938.1 - 0.11 11.4 28.4 0.16 10.9 28.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) GREB1 PF15782.5 EKX31938.1 - 0.12 9.4 17.7 0.16 9.0 17.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Membralin PF09746.9 EKX31938.1 - 0.13 11.3 12.7 0.21 10.6 12.7 1.3 1 0 0 1 1 1 0 Tumour-associated protein SLC12 PF03522.15 EKX31938.1 - 0.13 11.2 20.9 0.2 10.6 20.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DDRGK PF09756.9 EKX31938.1 - 0.13 11.8 36.6 0.24 11.0 36.6 1.3 1 0 0 1 1 1 0 DDRGK domain Mg_chelatase PF01078.21 EKX31938.1 - 0.16 11.3 0.0 0.16 11.3 0.0 2.6 2 1 0 2 2 1 0 Magnesium chelatase, subunit ChlI Pex14_N PF04695.13 EKX31938.1 - 0.17 12.6 34.4 0.39 11.4 34.4 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AAA_17 PF13207.6 EKX31938.1 - 0.2 12.1 0.0 0.2 12.1 0.0 3.1 3 0 0 3 3 2 0 AAA domain SpoIIP PF07454.11 EKX31938.1 - 0.23 10.9 23.4 0.36 10.2 23.4 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) PPP4R2 PF09184.11 EKX31938.1 - 0.23 11.0 11.3 0.37 10.3 11.3 1.2 1 0 0 1 1 1 0 PPP4R2 Plasmodium_Vir PF05795.11 EKX31938.1 - 0.24 10.8 6.6 0.37 10.2 6.6 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Lin-8 PF03353.15 EKX31938.1 - 0.26 10.8 25.2 0.43 10.1 25.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CCDC53 PF10152.9 EKX31938.1 - 0.26 11.7 22.4 0.53 10.7 22.4 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF908 PF06012.12 EKX31938.1 - 0.31 10.4 16.8 0.64 9.4 16.8 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Otopetrin PF03189.13 EKX31938.1 - 0.33 9.7 10.5 0.53 9.0 10.5 1.2 1 0 0 1 1 1 0 Otopetrin SID-1_RNA_chan PF13965.6 EKX31938.1 - 0.34 9.3 8.4 0.47 8.8 8.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 OATP PF03137.20 EKX31938.1 - 0.35 9.1 7.2 0.64 8.2 7.2 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MMU163 PF17119.5 EKX31938.1 - 0.37 9.9 8.8 0.73 8.9 8.8 1.4 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis CCSAP PF15748.5 EKX31938.1 - 0.43 10.7 22.4 0.77 9.9 22.4 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated TERB2 PF15101.6 EKX31938.1 - 0.45 10.5 26.6 1.1 9.3 26.6 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 NPR3 PF03666.13 EKX31938.1 - 0.51 9.1 19.4 0.78 8.5 19.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Sin_N PF04801.13 EKX31938.1 - 0.54 9.4 32.7 0.93 8.6 32.7 1.3 1 0 0 1 1 1 0 Sin-like protein conserved region DUF4050 PF13259.6 EKX31938.1 - 0.55 10.5 17.0 1 9.6 17.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Zip PF02535.22 EKX31938.1 - 0.64 9.2 7.9 0.98 8.6 7.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Gti1_Pac2 PF09729.9 EKX31938.1 - 0.64 10.1 19.3 1.3 9.1 19.3 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family ALMT PF11744.8 EKX31938.1 - 0.71 8.6 18.0 1.1 8.1 18.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Hid1 PF12722.7 EKX31938.1 - 0.8 7.8 19.1 1.1 7.3 19.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein eIF3_subunit PF08597.10 EKX31938.1 - 0.82 9.5 21.8 1.4 8.8 21.8 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Spore_coat_CotO PF14153.6 EKX31938.1 - 0.89 9.5 31.2 1.6 8.6 31.2 1.4 1 0 0 1 1 1 0 Spore coat protein CotO DUF3381 PF11861.8 EKX31938.1 - 0.95 9.2 23.9 1.8 8.3 23.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Ctr PF04145.15 EKX31938.1 - 1.3 9.6 10.9 3.1 8.4 10.9 1.7 1 0 0 1 1 1 0 Ctr copper transporter family AAA_24 PF13479.6 EKX31938.1 - 1.4 8.6 0.0 1.4 8.6 0.0 3.0 2 1 0 2 2 1 0 AAA domain Dynamin_N PF00350.23 EKX31938.1 - 1.4 8.9 12.6 5.5 7.0 7.1 2.7 2 0 0 2 2 2 0 Dynamin family DUF2126 PF09899.9 EKX31938.1 - 1.5 6.8 14.6 2.1 6.3 14.6 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF2828 PF11443.8 EKX31938.1 - 1.6 6.8 22.4 2.3 6.2 22.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Bul1_N PF04425.12 EKX31938.1 - 1.6 7.4 19.0 2.4 6.8 19.0 1.2 1 0 0 1 1 1 0 Bul1 N terminus AIF_C PF14721.6 EKX31938.1 - 1.7 9.0 15.8 4.3 7.7 15.8 1.7 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Connexin PF00029.19 EKX31938.1 - 1.9 8.2 17.9 3.1 7.5 17.9 1.2 1 0 0 1 1 1 0 Connexin MMR1 PF08505.10 EKX31938.1 - 2.4 8.4 24.3 4.8 7.4 24.3 1.5 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Calici_coat_C PF08435.11 EKX31938.1 - 2.5 7.6 15.5 8.1 5.9 15.5 1.8 2 0 0 2 2 1 0 Calicivirus coat protein C-terminal Afi1 PF07792.12 EKX31938.1 - 3 8.3 21.6 6.3 7.3 21.6 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PXA PF02194.15 EKX31938.1 - 3 7.8 13.9 7.6 6.5 13.9 1.6 1 0 0 1 1 1 0 PXA domain Baculo_PP31 PF05311.11 EKX31938.1 - 3 7.2 20.7 4.9 6.6 20.7 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) GBP_C PF02841.14 EKX31938.1 - 3.2 7.1 35.8 1.8 7.9 33.7 1.6 2 0 0 2 2 1 0 Guanylate-binding protein, C-terminal domain DUF4638 PF15472.6 EKX31938.1 - 3.4 7.3 21.7 6.6 6.4 21.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) PTPRCAP PF15713.5 EKX31938.1 - 4 7.7 24.6 8 6.7 24.6 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated BORG_CEP PF14957.6 EKX31938.1 - 4.4 8.5 15.2 11 7.2 15.2 1.7 1 0 0 1 1 1 0 Cdc42 effector Band_3_cyto PF07565.13 EKX31938.1 - 4.5 7.0 21.8 8.1 6.2 21.8 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain MDM10 PF12519.8 EKX31938.1 - 4.7 6.0 20.9 7.2 5.3 20.9 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Cellulose_synt PF03552.14 EKX31938.1 - 5.3 5.4 8.0 7.4 4.9 8.0 1.1 1 0 0 1 1 1 0 Cellulose synthase V_ATPase_I PF01496.19 EKX31938.1 - 6.5 4.5 26.7 8.9 4.1 26.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM60A PF15396.6 EKX31938.1 - 7.3 6.5 21.7 0.49 10.4 16.5 1.6 2 0 0 2 2 1 0 Protein Family FAM60A Pal1 PF08316.11 EKX31938.1 - 8.6 7.1 11.5 24 5.6 11.5 1.8 1 0 0 1 1 1 0 Pal1 cell morphology protein Paf1 PF03985.13 EKX31938.1 - 8.6 5.2 29.1 11 4.9 28.4 1.4 2 0 0 2 2 1 0 Paf1 DUF2464 PF10240.9 EKX31938.1 - 8.7 5.8 17.6 14 5.1 17.6 1.2 1 0 0 1 1 1 0 Multivesicular body subunit 12 CLN3 PF02487.17 EKX31938.1 - 9 5.2 19.6 14 4.6 19.6 1.2 1 0 0 1 1 1 0 CLN3 protein Phage_antitermQ PF06530.12 EKX31939.1 - 0.0072 16.2 0.0 0.18 11.7 0.0 2.7 2 0 0 2 2 2 1 Phage antitermination protein Q Methyltransf_12 PF08242.12 EKX31939.1 - 0.04 14.7 1.9 5 7.9 0.0 3.4 3 0 0 3 3 3 0 Methyltransferase domain PhaC_N PF07167.13 EKX31939.1 - 0.056 13.1 0.0 0.71 9.5 0.0 2.3 2 0 0 2 2 2 0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus Presenilin PF01080.17 EKX31940.1 - 0.12 11.2 13.9 0.16 10.7 13.9 1.1 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 EKX31940.1 - 0.46 10.5 4.5 0.62 10.1 4.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S49_N PF08496.10 EKX31940.1 - 0.6 10.2 13.8 0.42 10.7 6.3 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal eIF3_subunit PF08597.10 EKX31940.1 - 0.76 9.6 23.5 2.5 8.0 15.2 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit SprA-related PF12118.8 EKX31940.1 - 0.98 8.5 22.3 2.4 7.2 14.7 2.1 2 0 0 2 2 2 0 SprA-related family Prothymosin PF03247.14 EKX31940.1 - 1.1 9.7 31.3 1.2 9.6 24.1 2.1 2 0 0 2 2 2 0 Prothymosin/parathymosin family Trypan_PARP PF05887.11 EKX31940.1 - 1.2 9.1 11.9 1.9 8.5 11.9 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Afi1 PF07792.12 EKX31940.1 - 1.6 9.2 14.3 1.7 9.1 10.0 2.1 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking SAPS PF04499.15 EKX31940.1 - 1.7 7.4 11.8 2 7.1 11.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SID-1_RNA_chan PF13965.6 EKX31940.1 - 1.7 6.9 2.7 1.5 7.1 2.7 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FYDLN_acid PF09538.10 EKX31940.1 - 4.1 8.1 22.4 18 6.1 16.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) CPSF100_C PF13299.6 EKX31940.1 - 4.7 7.4 14.6 1.4 9.1 8.5 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF4820 PF16091.5 EKX31940.1 - 5 6.4 16.7 0.81 9.0 9.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) FKBP_N PF01346.18 EKX31940.1 - 5.2 8.1 18.7 1.2 10.2 10.1 2.2 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase TFB6 PF17110.5 EKX31940.1 - 5.7 6.7 12.3 2 8.2 7.7 2.0 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH SpoIIP PF07454.11 EKX31940.1 - 6.9 6.0 15.7 1.2 8.5 10.7 1.9 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) RNA_pol_Rpc4 PF05132.14 EKX31940.1 - 7 7.1 14.3 2.1 8.8 8.4 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 Pox_Ag35 PF03286.14 EKX31940.1 - 7.1 6.4 18.2 1.6 8.5 11.0 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein MRP-S26 PF14943.6 EKX31940.1 - 8.1 6.3 29.5 8.2 6.3 17.6 2.1 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 Spt20 PF12090.8 EKX31940.1 - 8.4 5.9 18.1 0.57 9.7 13.0 1.5 2 0 0 2 2 2 0 Spt20 family Enolase_C PF00113.22 EKX31943.1 - 5.8e-144 478.8 0.1 7.5e-144 478.4 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EKX31943.1 - 3.6e-43 146.9 0.2 5.9e-43 146.2 0.2 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EKX31943.1 - 3.2e-09 36.7 0.0 5.9e-09 35.8 0.0 1.5 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EKX31943.1 - 2.1e-05 23.8 0.4 0.00035 19.8 0.0 2.2 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Hpt PF01627.23 EKX31944.1 - 5.1e-17 61.9 5.2 1.3e-11 44.6 0.6 2.7 2 1 1 3 3 3 2 Hpt domain FAD-oxidase_C PF02913.19 EKX31944.1 - 0.011 15.4 0.8 0.017 14.8 0.8 1.2 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain CRM1_repeat PF18777.1 EKX31944.1 - 0.05 13.1 0.1 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat NRN1 PF15056.6 EKX31944.1 - 0.089 12.9 0.2 0.18 11.9 0.2 1.5 1 0 0 1 1 1 0 Neuritin protein family Cytochrom_B562 PF07361.11 EKX31944.1 - 0.1 13.3 5.8 3.9 8.2 1.1 3.0 2 1 0 2 2 2 0 Cytochrome b562 NRDD PF13597.6 EKX31944.1 - 0.13 11.0 0.1 0.18 10.6 0.1 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase SesA PF17107.5 EKX31944.1 - 0.25 11.5 1.8 15 5.8 0.0 2.9 2 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF3347 PF11827.8 EKX31944.1 - 1.4 9.1 5.2 1.5 9.0 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) PMEI PF04043.15 EKX31944.1 - 2.8 8.3 6.3 3.4 8.0 4.7 2.0 1 1 1 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Fer2_3 PF13085.6 EKX31945.1 - 1e-31 109.1 0.0 1.9e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EKX31945.1 - 3.6e-08 33.8 11.1 3.6e-08 33.8 11.1 2.1 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EKX31945.1 - 2.7e-07 30.6 7.1 2.7e-07 30.6 7.1 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EKX31945.1 - 1.8e-06 28.3 15.9 2.7e-06 27.7 12.7 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer2 PF00111.27 EKX31945.1 - 0.0066 16.4 0.8 0.0066 16.4 0.8 2.1 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 EKX31945.1 - 0.14 12.4 0.1 0.14 12.4 0.1 2.6 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 EKX31945.1 - 2.1 9.0 18.6 0.82 10.3 13.8 2.6 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 EKX31945.1 - 3 8.1 18.9 0.56 10.4 12.2 2.7 2 1 0 2 2 2 0 4Fe-4S dicluster domain bZIP_2 PF07716.15 EKX31948.1 - 0.4 10.8 3.1 0.8 9.8 3.1 1.5 1 0 0 1 1 1 0 Basic region leucine zipper gpD PF02925.16 EKX31949.1 - 0.084 12.8 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage scaffolding protein D DHHC PF01529.20 EKX31950.1 - 2.8e-20 72.8 12.7 3.2e-20 72.6 12.7 1.0 1 0 0 1 1 1 1 DHHC palmitoyltransferase PDZ PF00595.24 EKX31951.1 - 2.9e-09 37.2 0.0 1.8e-06 28.2 0.0 2.8 2 1 1 3 3 3 2 PDZ domain PDZ_6 PF17820.1 EKX31951.1 - 6.7e-07 29.1 0.0 0.047 13.5 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX31951.1 - 0.00076 19.7 0.0 0.028 14.7 0.0 2.7 2 1 1 3 3 3 1 PDZ domain Tricorn_PDZ PF14685.6 EKX31951.1 - 0.032 14.2 0.0 3.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Tricorn protease PDZ domain PDZ_1 PF12812.7 EKX31951.1 - 0.096 12.7 0.0 0.49 10.4 0.0 2.2 3 0 0 3 3 3 0 PDZ-like domain RWP-RK PF02042.15 EKX31952.1 - 1.9e-12 47.0 0.0 2.6e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 RWP-RK domain Brix PF04427.18 EKX31953.1 - 9.2e-22 78.1 0.0 1.2e-21 77.7 0.0 1.1 1 0 0 1 1 1 1 Brix domain GNT-I PF03071.15 EKX31954.1 - 2.8e-103 346.0 0.2 4.3e-103 345.4 0.2 1.2 1 0 0 1 1 1 1 GNT-I family Glyco_transf_54 PF04666.13 EKX31954.1 - 0.00011 21.2 1.7 0.0019 17.1 1.7 2.3 1 1 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Glycos_transf_2 PF00535.26 EKX31954.1 - 0.058 13.2 0.1 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 HR1 PF02185.16 EKX31954.1 - 0.092 12.9 1.3 0.21 11.7 0.7 1.9 1 1 0 1 1 1 0 Hr1 repeat Baculo_gp64 PF03273.13 EKX31954.1 - 0.14 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family ApoLp-III PF07464.11 EKX31956.1 - 0.019 15.0 0.1 0.035 14.2 0.0 1.5 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) RTP1_C1 PF10363.9 EKX31956.1 - 0.043 14.0 0.1 0.057 13.6 0.1 1.4 1 1 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 DNA_pol_phi PF04931.13 EKX31957.1 - 0.0038 15.4 31.5 0.0045 15.2 31.5 1.0 1 0 0 1 1 1 1 DNA polymerase phi Nop14 PF04147.12 EKX31957.1 - 0.0049 15.2 15.7 0.005 15.1 15.7 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 EKX31957.1 - 0.031 13.7 15.9 0.033 13.6 15.9 1.1 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.12 EKX31957.1 - 0.033 12.6 11.4 0.034 12.6 11.4 1.1 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 EKX31957.1 - 0.057 12.8 11.7 0.054 12.8 11.7 1.1 1 0 0 1 1 1 0 BUD22 PI3K_1B_p101 PF10486.9 EKX31957.1 - 2.5 5.8 3.7 2.6 5.7 3.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit eIF-3c_N PF05470.12 EKX31957.1 - 2.6 6.2 6.5 2.8 6.1 6.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2457 PF10446.9 EKX31957.1 - 5.6 6.0 44.1 7.3 5.6 44.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) GCS PF03074.16 EKX31959.1 - 0.18 11.1 0.3 0.24 10.8 0.3 1.1 1 0 0 1 1 1 0 Glutamate-cysteine ligase OmdA PF13376.6 EKX31960.1 - 0.086 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated DNA_pol_phi PF04931.13 EKX31962.1 - 4.6 5.2 20.5 5.4 5.0 20.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF1786 PF08735.10 EKX31963.1 - 0.071 12.4 2.1 0.065 12.5 1.2 1.3 1 1 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) TFIIA PF03153.13 EKX31963.1 - 1.6 8.6 16.9 2.1 8.3 16.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CemA PF03040.14 EKX31963.1 - 6.1 6.7 6.8 9.2 6.1 6.8 1.3 1 0 0 1 1 1 0 CemA family AMP-binding PF00501.28 EKX31964.1 - 9.4e-82 274.8 0.0 1.6e-81 274.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EKX31964.1 - 0.00011 23.1 0.1 0.00057 20.8 0.0 2.3 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain ubiquitin PF00240.23 EKX31967.1 - 3.3e-33 113.3 0.5 4.4e-33 112.8 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EKX31967.1 - 3.2e-16 58.9 0.7 5e-16 58.3 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-AN1 PF01428.16 EKX31967.1 - 1.9e-10 40.7 11.8 3.1e-10 40.0 11.8 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Ubiquitin_2 PF14560.6 EKX31967.1 - 0.00016 22.1 0.1 0.00062 20.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EKX31967.1 - 0.0061 16.5 0.0 0.0086 16.0 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EKX31967.1 - 0.0083 16.2 0.2 0.024 14.7 0.0 1.9 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EKX31967.1 - 0.012 15.9 0.1 0.019 15.3 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain Transp_Tc5_C PF04236.15 EKX31967.1 - 0.018 15.4 3.8 0.035 14.5 3.8 1.4 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain DUF2407 PF10302.9 EKX31967.1 - 0.033 14.7 0.0 0.035 14.7 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EKX31967.1 - 0.13 12.3 1.0 13 5.9 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain Ribosomal_L37ae PF01780.19 EKX31967.1 - 0.44 10.7 4.3 0.32 11.1 1.9 2.0 2 1 1 3 3 3 0 Ribosomal L37ae protein family SseC PF04888.12 EKX31968.1 - 2.4 7.7 6.7 3.2 7.2 6.7 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family AAA_18 PF13238.6 EKX31969.1 - 0.0027 18.2 0.0 0.0056 17.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EKX31969.1 - 0.0074 16.3 0.1 0.038 14.0 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EKX31969.1 - 0.022 14.6 0.0 0.057 13.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EKX31969.1 - 0.042 14.2 0.3 0.1 13.0 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EKX31969.1 - 0.044 13.5 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EKX31969.1 - 0.063 12.8 0.3 0.18 11.4 0.3 1.8 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 EKX31969.1 - 0.065 12.6 0.1 0.34 10.2 0.0 2.0 2 1 0 2 2 2 0 KaiC IstB_IS21 PF01695.17 EKX31969.1 - 0.079 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.29 EKX31969.1 - 0.11 13.0 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX31969.1 - 0.17 12.3 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Comm PF15957.5 EKX31971.1 - 0.019 15.3 3.8 0.039 14.3 0.0 2.2 2 0 0 2 2 2 0 Commissureless DUF4483 PF14825.6 EKX31971.1 - 0.13 12.0 0.0 6.2 6.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4483) DA1-like PF12315.8 EKX31971.1 - 0.17 11.2 0.0 15 4.9 0.0 2.1 2 0 0 2 2 2 0 Protein DA1 7tm_7 PF08395.12 EKX31971.1 - 2.9 7.0 12.0 0.099 11.8 1.6 2.0 2 0 0 2 2 2 0 7tm Chemosensory receptor DUF4726 PF15855.5 EKX31972.1 - 0.0078 16.4 0.3 0.025 14.8 0.1 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4726) zf-RING_2 PF13639.6 EKX31973.1 - 1.5e-12 47.6 11.3 3.4e-12 46.5 11.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX31973.1 - 6.3e-09 35.5 9.9 1.3e-08 34.6 9.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX31973.1 - 2.2e-08 34.0 7.2 4.8e-08 32.9 7.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EKX31973.1 - 3.6e-08 33.6 11.5 1.4e-07 31.7 11.5 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EKX31973.1 - 5.9e-08 32.5 9.0 1.4e-07 31.2 9.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EKX31973.1 - 1.5e-06 27.9 5.5 4e-06 26.5 5.5 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EKX31973.1 - 4e-06 26.6 7.6 1.1e-05 25.2 7.5 1.7 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EKX31973.1 - 3.4e-05 23.4 6.2 8.3e-05 22.1 6.2 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EKX31973.1 - 0.00011 22.0 7.0 0.00023 20.9 7.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EKX31973.1 - 0.00055 19.8 7.3 0.0011 18.8 7.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Rtf2 PF04641.12 EKX31973.1 - 0.0038 16.6 0.7 0.0053 16.2 0.7 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-ANAPC11 PF12861.7 EKX31973.1 - 0.0069 16.4 5.7 0.023 14.7 5.7 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EKX31973.1 - 0.021 15.0 7.1 0.049 13.8 7.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EKX31973.1 - 0.068 13.0 4.3 0.19 11.6 4.3 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 EKX31973.1 - 0.35 11.0 7.6 0.74 10.0 7.6 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 EKX31973.1 - 0.64 10.2 5.1 3 8.1 5.1 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 EKX31973.1 - 1 9.7 6.9 2.6 8.4 6.9 1.8 1 0 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.5 EKX31973.1 - 6.8 6.8 6.9 15 5.7 6.9 1.7 1 0 0 1 1 1 0 Zinc-finger Paramyxo_ncap PF00973.19 EKX31975.1 - 1.1 8.0 7.5 1.6 7.6 7.5 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Methyltransf_21 PF05050.12 EKX31976.1 - 8.3e-07 29.2 0.0 1.6e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_22 PF13383.6 EKX31976.1 - 6.5e-05 22.6 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Myosin_head PF00063.21 EKX31977.1 - 1.4e-184 615.1 0.0 3.6e-184 613.7 0.0 1.5 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 EKX31977.1 - 0.00019 21.2 0.1 0.00035 20.4 0.1 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 EKX31977.1 - 0.0002 21.8 0.3 0.00093 19.6 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EKX31977.1 - 0.0027 18.0 0.0 0.0082 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EKX31977.1 - 0.0047 16.0 0.0 0.0088 15.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 EKX31977.1 - 0.021 14.1 0.5 0.14 11.4 0.1 2.3 2 1 0 2 2 2 0 Zeta toxin TsaE PF02367.17 EKX31977.1 - 0.044 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 EKX31977.1 - 0.057 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 EKX31977.1 - 0.12 12.4 0.2 0.26 11.4 0.2 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_6 PF12774.7 EKX31977.1 - 0.14 11.1 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region RNA_helicase PF00910.22 EKX31977.1 - 0.18 12.2 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 EKX31977.1 - 0.18 11.3 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Methyltransf_21 PF05050.12 EKX31978.1 - 2.3e-15 57.0 0.0 9.5e-15 55.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase FkbM domain Meleagrin PF08189.11 EKX31980.1 - 0.14 11.9 1.9 0.28 10.9 0.1 2.4 2 0 0 2 2 2 0 Meleagrin/Cygnin family PI31_Prot_N PF11566.8 EKX31981.1 - 1.2e-20 74.0 0.0 1.7e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal Takusan PF04822.13 EKX31983.1 - 9.8e-13 47.8 24.6 0.35 10.8 0.0 8.0 7 1 1 8 8 8 5 Takusan MalF_P2 PF14785.6 EKX31983.1 - 0.0019 18.2 22.8 5.7 7.0 4.4 5.8 2 2 3 5 5 5 5 Maltose transport system permease protein MalF P2 domain Striatin PF08232.12 EKX31983.1 - 0.065 13.8 0.0 0.065 13.8 0.0 8.0 3 1 5 8 8 8 0 Striatin family zf-ribbon_3 PF13248.6 EKX31983.1 - 7.2 6.2 7.8 0.22 11.0 0.9 2.2 2 0 0 2 2 2 0 zinc-ribbon domain HscB_4_cys PF18256.1 EKX31983.1 - 8.7 6.3 7.5 5.1 7.0 0.3 2.9 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif Pkinase PF00069.25 EKX31984.1 - 1.2e-20 74.0 0.0 3.4e-20 72.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX31984.1 - 4.2e-07 29.5 0.0 1.2e-05 24.7 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase WW PF00397.26 EKX31984.1 - 1.2e-06 28.4 4.4 1.2e-06 28.4 4.4 1.9 2 0 0 2 2 2 1 WW domain Kinase-like PF14531.6 EKX31984.1 - 0.0021 17.4 0.0 0.0041 16.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EKX31984.1 - 0.0097 14.7 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX31984.1 - 0.013 15.5 1.1 0.022 14.7 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EKX31984.1 - 0.02 14.3 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 EKX31985.1 - 9.4e-30 103.2 0.0 2.5e-29 101.8 0.0 1.7 2 0 0 2 2 2 1 ABC1 family APH PF01636.23 EKX31985.1 - 1.7e-05 24.9 0.0 0.00012 22.1 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EKX31985.1 - 0.00048 19.6 0.0 0.018 14.4 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX31985.1 - 0.092 12.0 0.0 0.44 9.8 0.0 2.0 1 1 0 1 1 1 0 Protein tyrosine kinase Vps54 PF07928.12 EKX31987.1 - 2e-44 151.3 0.5 2e-44 151.3 0.5 2.4 2 0 0 2 2 2 1 Vps54-like protein Vps54_N PF10475.9 EKX31987.1 - 2.8e-09 36.7 4.3 2.8e-09 36.7 4.3 1.9 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 EKX31987.1 - 0.0001 22.2 1.6 0.00013 21.8 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Sec15 PF04091.12 EKX31987.1 - 0.0044 16.5 0.2 0.013 14.9 0.2 1.8 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like CCDC-167 PF15188.6 EKX31987.1 - 0.071 13.5 1.4 0.34 11.3 1.4 2.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF3510 PF12022.8 EKX31987.1 - 0.38 11.1 2.8 0.69 10.3 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3510) COG2 PF06148.11 EKX31987.1 - 2.8 8.0 8.6 3.7 7.7 5.9 2.7 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF5385 PF17359.2 EKX31989.1 - 0.013 15.0 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) FtsL PF04999.13 EKX31989.1 - 0.12 12.4 0.1 0.14 12.2 0.1 1.1 1 0 0 1 1 1 0 Cell division protein FtsL Cytomega_TRL10 PF06084.11 EKX31989.1 - 0.13 12.3 0.1 0.19 11.7 0.0 1.2 1 1 0 1 1 1 0 Cytomegalovirus TRL10 protein DUF3149 PF11346.8 EKX31989.1 - 1.1 9.0 4.2 1.9 8.2 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) U-box PF04564.15 EKX31990.1 - 3.3e-17 62.4 0.1 4e-17 62.2 0.1 1.1 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX31990.1 - 0.0016 18.2 0.2 0.0065 16.3 0.2 1.9 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 EKX31990.1 - 0.048 13.8 0.0 0.064 13.4 0.0 1.1 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Lipase_3 PF01764.25 EKX31991.1 - 1.9e-12 47.3 0.0 3.2e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 EKX31991.1 - 0.056 13.0 0.0 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 EKX31991.1 - 0.066 12.5 0.0 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MNNL PF07657.13 EKX31991.1 - 0.077 13.0 0.2 6.2 6.9 0.0 2.2 2 0 0 2 2 2 0 N terminus of Notch ligand PAF-AH_p_II PF03403.13 EKX31991.1 - 0.18 10.3 0.0 0.26 9.7 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF4766 PF15973.5 EKX31991.1 - 1.9 9.1 9.5 7 7.3 9.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4766) PUF PF00806.19 EKX31992.1 - 9.1e-66 214.0 3.6 2.3e-08 33.3 0.0 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 EKX31992.1 - 1.1e-05 25.8 0.1 0.053 13.9 0.0 4.0 1 1 3 4 4 4 1 CPL (NUC119) domain DUF577 PF04510.12 EKX31992.1 - 0.0008 19.4 0.1 0.097 12.6 0.0 2.5 1 1 1 2 2 2 1 Family of unknown function (DUF577) sCache_2 PF17200.4 EKX31992.1 - 0.02 14.8 0.0 3.6 7.4 0.0 3.5 4 0 0 4 4 4 0 Single Cache domain 2 TBPIP PF07106.13 EKX31992.1 - 0.023 14.7 1.5 2.8 7.9 0.0 4.7 8 0 0 8 8 8 0 TBPIP/Hop2 winged helix domain DUF5332 PF17266.2 EKX31992.1 - 0.11 12.2 0.2 0.27 10.9 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5332) DMA PF03474.14 EKX31992.1 - 0.12 12.0 4.3 12 5.6 0.0 4.3 5 0 0 5 5 5 0 DMRTA motif Med18 PF09637.10 EKX31993.1 - 0.043 13.6 0.3 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Med18 protein DUF2188 PF09954.9 EKX31994.1 - 0.043 14.0 0.2 0.072 13.2 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) DUF2188 PF09954.9 EKX31997.1 - 0.011 15.8 0.5 0.023 14.8 0.5 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) bZIP_1 PF00170.21 EKX31998.1 - 4e-11 42.8 17.0 4e-11 42.8 17.0 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 EKX31998.1 - 2.4e-06 27.9 5.9 4.8e-06 27.0 5.9 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 EKX31998.1 - 3.6e-06 27.0 14.5 1.1e-05 25.4 14.4 1.9 1 1 0 1 1 1 1 Basic region leucine zipper DUF737 PF05300.11 EKX31998.1 - 1.6 9.1 8.9 3.2 8.1 8.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF737) APG6_N PF17675.1 EKX31998.1 - 3.5 8.1 11.8 0.74 10.4 8.0 1.7 2 0 0 2 2 2 0 Apg6 coiled-coil region TTL PF03133.15 EKX32000.1 - 2.7e-21 76.0 0.0 3.5e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 EKX32000.1 - 1.4e-06 27.8 0.0 1.7e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EKX32000.1 - 2.3e-06 27.8 0.0 3.5e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_YheCD PF14398.6 EKX32000.1 - 0.0051 16.1 0.0 0.0063 15.8 0.0 1.2 1 0 0 1 1 1 1 YheC/D like ATP-grasp GSH-S_ATP PF02955.16 EKX32000.1 - 0.024 14.0 0.0 0.041 13.3 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain RimK PF08443.11 EKX32000.1 - 0.13 11.9 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 RimK-like ATP-grasp domain U-box PF04564.15 EKX32001.1 - 4.7e-18 65.1 0.0 7.3e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.28 EKX32001.1 - 1.1e-08 34.5 7.6 0.00022 20.9 1.4 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX32001.1 - 5.8e-08 32.3 4.1 2.5e-05 23.8 1.8 2.5 2 0 0 2 2 2 2 TPR repeat TPR_17 PF13431.6 EKX32001.1 - 6.5e-07 29.3 3.0 0.0073 16.6 0.3 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX32001.1 - 6.7e-06 25.8 6.7 0.0098 15.9 1.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-NOSIP PF15906.5 EKX32001.1 - 0.00068 19.7 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein TPR_19 PF14559.6 EKX32001.1 - 0.0027 18.2 5.5 0.18 12.3 1.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX32001.1 - 0.0044 17.2 5.0 0.0088 16.2 5.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EKX32001.1 - 0.024 14.8 0.2 0.065 13.4 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX32001.1 - 0.046 14.0 4.0 0.1 12.9 0.6 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EKX32001.1 - 0.15 12.7 3.8 0.67 10.6 2.2 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX32001.1 - 0.2 12.6 1.8 5.4 8.1 0.1 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX32001.1 - 0.23 11.8 5.8 1.7 9.1 0.1 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EKX32001.1 - 0.33 11.1 4.2 2.1 8.5 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX32001.1 - 2.7 8.8 5.1 84 4.1 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1499 PF07386.11 EKX32002.1 - 8e-19 68.3 0.0 9e-19 68.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) EFG_II PF14492.6 EKX32002.1 - 0.013 15.6 0.1 0.031 14.4 0.1 1.6 2 0 0 2 2 2 0 Elongation Factor G, domain II DUF3892 PF13031.6 EKX32002.1 - 0.033 14.8 0.1 3 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3892) RRM_3 PF08777.11 EKX32002.1 - 0.041 13.9 0.2 0.16 12.0 0.2 1.8 2 0 0 2 2 2 0 RNA binding motif ATP_transf PF09830.9 EKX32003.1 - 0.043 14.0 0.0 0.075 13.2 0.0 1.4 1 0 0 1 1 1 0 ATP adenylyltransferase Acyltransferase PF01553.21 EKX32004.1 - 1.1e-11 44.5 0.0 1.6e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase HECT PF00632.25 EKX32006.1 - 1.9e-97 326.4 0.0 2.4e-97 326.1 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) FNIP_C PF14638.6 EKX32007.1 - 0.03 13.9 0.1 0.043 13.5 0.1 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus Rad1 PF02144.16 EKX32009.1 - 5.9e-43 146.9 0.4 7.3e-43 146.6 0.4 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 PCNA_N PF00705.18 EKX32009.1 - 0.0032 17.2 0.1 0.0083 15.8 0.0 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 EKX32009.1 - 0.066 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, C-terminal domain EF-hand_4 PF12763.7 EKX32010.1 - 6.4e-15 55.0 0.0 6.7e-15 54.9 0.0 1.0 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_6 PF13405.6 EKX32010.1 - 5.4e-09 35.3 0.1 0.0016 18.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EKX32010.1 - 3.1e-08 32.6 0.0 0.002 17.5 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX32010.1 - 5.1e-08 33.3 0.0 7.7e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX32010.1 - 8.2e-05 21.9 0.2 0.22 11.1 0.1 2.8 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EKX32010.1 - 0.0031 17.3 0.0 0.18 11.6 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain pair PGM_PMM_III PF02880.16 EKX32010.1 - 0.067 13.4 0.0 0.38 10.9 0.0 2.0 1 1 1 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III SAM_Exu PF18609.1 EKX32010.1 - 0.12 12.5 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Exuperantia SAM-like domain EF-hand_4 PF12763.7 EKX32011.1 - 4.5e-10 39.4 0.0 4.8e-10 39.3 0.0 1.0 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_6 PF13405.6 EKX32011.1 - 6.4e-08 31.9 0.0 0.0057 16.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EKX32011.1 - 1.6e-05 25.3 0.0 2.8e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX32011.1 - 4.5e-05 22.7 0.0 0.011 15.2 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EKX32011.1 - 0.032 13.7 0.1 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 EF hand EF-hand_10 PF14788.6 EKX32011.1 - 0.1 12.4 0.1 4 7.4 0.0 2.1 2 0 0 2 2 2 0 EF hand HD PF01966.22 EKX32012.1 - 2.4e-11 43.9 0.1 3.2e-11 43.5 0.1 1.1 1 0 0 1 1 1 1 HD domain PDEase_I PF00233.19 EKX32012.1 - 0.0023 17.7 0.0 0.0032 17.2 0.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Pkinase PF00069.25 EKX32013.1 - 8.8e-22 77.7 0.0 3.5e-21 75.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX32013.1 - 1.7e-17 63.5 0.0 6.9e-08 32.1 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Asparaginase PF00710.20 EKX32015.1 - 2.7e-50 170.6 0.0 9e-50 168.9 0.0 1.7 2 0 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EKX32015.1 - 2.3e-27 95.5 0.1 3.9e-27 94.7 0.1 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ion_trans PF00520.31 EKX32017.1 - 5e-122 405.8 51.9 1.9e-46 158.3 11.1 4.2 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 EKX32017.1 - 2.1e-07 30.0 3.5 2.1e-07 30.0 3.5 5.2 5 1 0 5 5 5 3 Polycystin cation channel GPHH PF16905.5 EKX32017.1 - 0.053 13.3 0.0 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated Rotamase PF00639.21 EKX32017.1 - 0.08 13.9 4.3 0.28 12.2 4.3 1.9 1 0 0 1 1 1 0 PPIC-type PPIASE domain EF-hand_1 PF00036.32 EKX32017.1 - 0.084 12.5 0.5 0.31 10.7 0.0 2.3 2 0 0 2 2 2 0 EF hand DUF92 PF01940.16 EKX32017.1 - 0.14 11.6 4.3 1.3 8.4 0.0 3.0 3 0 0 3 3 3 0 Integral membrane protein DUF92 DUF719 PF05334.13 EKX32017.1 - 0.65 10.2 5.5 4.6 7.4 1.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Pyrid_oxidase_2 PF13883.6 EKX32021.1 - 6.3e-16 58.8 0.0 1.5e-15 57.5 0.0 1.7 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 EKX32021.1 - 9.2e-07 29.0 0.0 1.7e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Bac_rhodopsin PF01036.18 EKX32022.1 - 2.4e-09 37.1 14.2 1.5e-06 27.9 14.2 2.4 1 1 0 1 1 1 1 Bacteriorhodopsin-like protein GET2 PF08690.10 EKX32022.1 - 0.076 12.7 16.7 0.11 12.1 16.7 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 DUF3918 PF13056.6 EKX32022.1 - 2.8 7.6 8.3 0.16 11.6 1.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) PBP1_TM PF14812.6 EKX32022.1 - 4.6 7.7 10.9 0.16 12.3 4.8 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Bac_rhodopsin PF01036.18 EKX32023.1 - 1.7e-09 37.6 14.8 3.6e-06 26.7 0.6 2.4 1 1 0 2 2 2 2 Bacteriorhodopsin-like protein Bact_lectin PF18483.1 EKX32024.1 - 9.9e-08 32.2 0.0 2.7e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 Bacterial lectin RCC1 PF00415.18 EKX32024.1 - 1e-07 32.4 0.6 0.0095 16.5 0.0 2.6 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX32024.1 - 0.00019 21.1 2.9 0.12 12.3 0.1 2.6 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat Lectin_legB PF00139.19 EKX32024.1 - 0.0014 18.2 0.1 0.004 16.7 0.0 1.7 2 0 0 2 2 2 1 Legume lectin domain DUF1415 PF07209.12 EKX32025.1 - 2.9e-12 46.7 0.0 4e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1415) DLIC PF05783.11 EKX32026.1 - 1.5e-18 66.9 4.0 9.3e-07 28.0 0.0 3.0 1 1 2 3 3 3 3 Dynein light intermediate chain (DLIC) Lipase_GDSL_2 PF13472.6 EKX32027.1 - 0.0027 18.1 0.0 0.0059 17.0 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Filamin PF00630.19 EKX32027.1 - 0.016 16.0 0.0 0.1 13.4 0.0 2.3 2 0 0 2 2 2 0 Filamin/ABP280 repeat Big_3_5 PF16640.5 EKX32027.1 - 0.13 12.4 0.1 0.4 10.9 0.0 1.7 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) DUF3070 PF11270.8 EKX32027.1 - 4.1 7.7 6.5 1.1 9.6 1.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3070) Mito_carr PF00153.27 EKX32028.1 - 1.2e-50 169.4 0.1 2.5e-20 72.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein LRR_6 PF13516.6 EKX32029.1 - 2.7e-18 64.4 21.0 0.0096 15.9 0.7 8.3 8 0 0 8 8 8 6 Leucine Rich repeat LRR_4 PF12799.7 EKX32029.1 - 4.2e-09 36.5 14.3 0.25 11.8 0.0 5.6 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX32029.1 - 9.1e-07 28.6 23.0 0.026 14.3 1.7 7.4 3 2 4 7 7 7 4 Leucine rich repeat LRR_9 PF14580.6 EKX32029.1 - 0.0014 18.2 0.5 0.038 13.5 0.0 2.5 2 2 0 2 2 2 1 Leucine-rich repeat Tti2 PF10521.9 EKX32029.1 - 0.033 13.7 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Tti2 family PGA_cap PF09587.10 EKX32029.1 - 0.2 11.1 0.1 2.4 7.5 0.0 2.4 2 1 1 3 3 3 0 Bacterial capsule synthesis protein PGA_cap LRR_1 PF00560.33 EKX32029.1 - 0.41 11.4 12.7 54 4.9 0.2 6.6 7 0 0 7 7 7 0 Leucine Rich Repeat Glyco_transf_22 PF03901.17 EKX32030.1 - 2e-51 175.5 17.0 3e-49 168.4 14.8 2.1 2 0 0 2 2 2 2 Alg9-like mannosyltransferase family Spt4 PF06093.13 EKX32031.1 - 0.11 12.7 0.1 0.25 11.5 0.0 1.6 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger IRF-2BP1_2 PF11261.8 EKX32031.1 - 3.5 7.2 4.7 78 2.9 0.1 3.2 3 0 0 3 3 3 0 Interferon regulatory factor 2-binding protein zinc finger Sod_Fe_C PF02777.18 EKX32032.1 - 3.2e-34 117.1 0.2 6.5e-34 116.2 0.1 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EKX32032.1 - 7.8e-21 74.4 1.0 1.4e-20 73.6 0.1 1.9 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain CRCB PF02537.15 EKX32033.1 - 3.9e-25 88.0 14.6 8.8e-14 51.6 0.9 2.5 3 0 0 3 3 3 2 CrcB-like protein, Camphor Resistance (CrcB) DUF2568 PF10823.8 EKX32034.1 - 0.0029 17.9 6.3 0.013 15.7 2.7 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF2568) Ank_2 PF12796.7 EKX32036.1 - 1.4e-19 70.5 1.9 2.4e-11 44.1 0.6 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX32036.1 - 9.6e-19 67.5 1.4 5.2e-06 26.9 0.2 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX32036.1 - 2e-14 52.3 3.3 0.0017 18.6 0.1 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 EKX32036.1 - 8.6e-13 48.1 9.0 4.6e-05 23.7 0.2 3.8 3 1 1 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EKX32036.1 - 1.3e-12 47.7 8.1 0.0021 18.3 0.1 4.6 2 1 3 5 5 5 4 Ankyrin repeats (many copies) HtrL_YibB PF09612.10 EKX32036.1 - 0.15 11.6 0.4 14 5.1 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (HtrL_YibB) Csm2_III-A PF03750.13 EKX32036.1 - 0.57 11.0 3.2 1.8 9.4 0.0 2.9 4 0 0 4 4 4 0 Csm2 Type III-A FAM176 PF14851.6 EKX32038.1 - 0.055 13.1 2.2 0.61 9.7 0.0 2.7 2 1 0 2 2 2 0 FAM176 family Sigma70_ner PF04546.13 EKX32038.1 - 0.12 12.3 1.7 0.22 11.4 1.7 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region YL1 PF05764.13 EKX32038.1 - 2.7 8.0 5.1 5.8 7.0 5.1 1.5 1 0 0 1 1 1 0 YL1 nuclear protein E1-E2_ATPase PF00122.20 EKX32039.1 - 3.5e-46 157.0 1.7 3.5e-46 157.0 1.7 3.5 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EKX32039.1 - 6.5e-18 65.8 0.0 2.9e-17 63.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EKX32039.1 - 1.8e-13 50.0 0.0 5.4e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EKX32039.1 - 8.4e-05 22.4 0.0 0.0022 17.8 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3377 PF11857.8 EKX32039.1 - 0.92 9.5 3.1 4.5 7.3 3.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Ephrin_rec_like PF07699.13 EKX32041.1 - 6e-48 160.4 90.3 4.8e-12 45.4 3.7 10.2 9 1 1 10 10 10 9 Putative ephrin-receptor like NCD3G PF07562.14 EKX32041.1 - 0.23 11.5 91.3 0.36 10.8 2.6 11.2 5 3 5 12 12 11 0 Nine Cysteines Domain of family 3 GPCR Apolipoprotein PF01442.18 EKX32042.1 - 0.025 14.4 0.5 0.037 13.9 0.5 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain AKNA PF12443.8 EKX32042.1 - 0.073 13.7 0.5 0.15 12.7 0.5 1.5 1 0 0 1 1 1 0 AT-hook-containing transcription factor TolA_bind_tri PF16331.5 EKX32042.1 - 0.086 12.9 0.3 0.18 11.9 0.3 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation Baculo_PEP_C PF04513.12 EKX32042.1 - 0.12 12.4 0.6 0.18 11.8 0.6 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus BBS1 PF14779.6 EKX32042.1 - 0.17 11.3 1.3 0.25 10.7 1.3 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 Pkinase PF00069.25 EKX32044.1 - 8.2e-23 81.1 0.0 1.4e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX32044.1 - 4e-11 42.7 0.0 6.9e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX32044.1 - 0.026 13.9 0.4 0.083 12.2 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family PRY PF13765.6 EKX32044.1 - 0.029 14.0 0.0 78 3.0 0.0 4.4 1 1 3 4 4 4 0 SPRY-associated domain APH PF01636.23 EKX32044.1 - 0.062 13.2 0.0 0.15 12.0 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX32044.1 - 0.12 11.1 0.0 0.12 11.1 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase DUF1521 PF07481.11 EKX32044.1 - 0.13 12.3 5.5 3.6 7.6 0.7 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1521) Pkinase PF00069.25 EKX32045.1 - 0.00023 20.6 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain NHL PF01436.21 EKX32046.1 - 5.9e-07 29.2 4.9 0.29 11.2 0.2 4.9 4 1 0 4 4 4 3 NHL repeat Ldl_recept_b PF00058.17 EKX32046.1 - 0.14 12.7 0.4 1.5 9.3 0.1 2.8 2 0 0 2 2 2 0 Low-density lipoprotein receptor repeat class B EXS PF03124.14 EKX32047.1 - 1.9 7.7 8.5 1.6 8.0 7.2 1.4 1 1 1 2 2 2 0 EXS family Flt3_lig PF02947.14 EKX32048.1 - 0.087 13.0 0.8 0.44 10.7 0.2 2.3 1 1 2 3 3 3 0 flt3 ligand ALO PF04030.14 EKX32050.1 - 0.067 13.0 0.7 0.36 10.6 0.1 2.1 1 1 1 2 2 2 0 D-arabinono-1,4-lactone oxidase Dynein_C PF18199.1 EKX32050.1 - 0.094 11.9 2.3 0.97 8.6 1.6 2.2 2 0 0 2 2 2 0 Dynein heavy chain C-terminal domain PI3K_P85_iSH2 PF16454.5 EKX32050.1 - 0.095 12.3 10.4 0.078 12.6 8.2 1.9 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain LMBR1 PF04791.16 EKX32050.1 - 0.15 11.0 3.9 0.29 10.0 3.9 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Fib_alpha PF08702.10 EKX32050.1 - 6.5 6.9 8.9 39 4.4 0.3 3.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family OmpH PF03938.14 EKX32050.1 - 8.4 6.7 14.5 0.43 10.9 2.8 3.5 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) TolA_bind_tri PF16331.5 EKX32052.1 - 0.0027 17.8 3.3 0.0082 16.2 0.7 2.4 2 0 0 2 2 2 1 TolA binding protein trimerisation DivIC PF04977.15 EKX32052.1 - 0.015 15.1 4.7 1.9 8.3 0.2 2.5 2 0 0 2 2 2 0 Septum formation initiator PhaP_Bmeg PF09602.10 EKX32052.1 - 0.048 13.6 2.9 0.06 13.3 1.9 1.5 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) ZapB PF06005.12 EKX32052.1 - 0.061 13.8 6.4 0.34 11.4 1.4 2.6 2 0 0 2 2 2 0 Cell division protein ZapB Ax_dynein_light PF10211.9 EKX32052.1 - 0.074 13.0 4.3 0.083 12.8 1.8 2.2 2 0 0 2 2 2 0 Axonemal dynein light chain UPF0184 PF03670.13 EKX32052.1 - 0.15 12.4 2.4 1.4 9.4 2.1 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) Atg14 PF10186.9 EKX32052.1 - 0.3 10.1 2.7 8.3 5.4 0.1 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 BBS1 PF14779.6 EKX32052.1 - 0.3 10.5 0.9 0.45 9.9 0.9 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 Nup54 PF13874.6 EKX32052.1 - 0.35 11.0 5.7 0.15 12.2 2.7 1.8 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 DUF948 PF06103.11 EKX32052.1 - 0.66 10.3 2.2 0.71 10.2 0.9 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) AKNA PF12443.8 EKX32052.1 - 1.1 10.0 4.6 0.5 11.1 1.1 2.2 2 1 1 3 3 2 0 AT-hook-containing transcription factor Herpes_BLRF2 PF05812.12 EKX32052.1 - 1.1 9.4 5.3 1.4 9.1 0.1 2.8 3 0 0 3 3 3 0 Herpesvirus BLRF2 protein SlyX PF04102.12 EKX32052.1 - 1.2 9.8 5.5 5.5 7.7 0.1 2.7 2 1 0 2 2 2 0 SlyX YabA PF06156.13 EKX32052.1 - 2 9.1 11.3 12 6.6 4.5 2.5 1 1 1 2 2 2 0 Initiation control protein YabA Spc24 PF08286.11 EKX32052.1 - 2.4 8.4 5.3 1.6 9.0 1.3 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 KIAA1430 PF13879.6 EKX32052.1 - 2.9 8.7 10.4 9.4 7.1 10.4 1.9 1 1 0 1 1 1 0 KIAA1430 homologue Ephrin_rec_like PF07699.13 EKX32054.1 - 1.8e-45 152.4 111.8 1.5e-06 27.8 2.6 10.9 1 1 11 12 12 12 12 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX32054.1 - 0.0016 18.8 77.6 0.079 13.4 0.7 12.7 5 5 7 13 13 13 6 TNFR/NGFR cysteine-rich region VSP PF03302.13 EKX32054.1 - 0.098 11.5 82.2 0.16 10.8 25.7 4.2 1 1 3 4 4 4 0 Giardia variant-specific surface protein NHL PF01436.21 EKX32055.1 - 2.1e-08 33.8 3.7 1.8e-05 24.5 0.0 4.1 5 1 0 5 5 5 2 NHL repeat Arylesterase PF01731.20 EKX32055.1 - 0.023 14.9 0.0 0.046 13.9 0.0 1.5 1 0 0 1 1 1 0 Arylesterase RICTOR_M PF14666.6 EKX32059.1 - 0.0034 17.1 1.7 0.41 10.4 0.3 2.3 2 0 0 2 2 2 2 Rapamycin-insensitive companion of mTOR, middle domain DUF3522 PF12036.8 EKX32061.1 - 1.1e-27 97.5 0.2 1.4e-27 97.2 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) 7TMR-DISM_7TM PF07695.11 EKX32061.1 - 0.00076 19.4 3.7 0.0046 16.9 3.7 2.0 1 1 0 1 1 1 1 7TM diverse intracellular signalling Erythro-docking PF09277.11 EKX32062.1 - 0.088 12.7 0.7 0.84 9.6 0.1 2.8 1 1 1 2 2 2 0 Erythronolide synthase, docking IL11 PF07400.11 EKX32062.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Interleukin 11 Ank_4 PF13637.6 EKX32064.1 - 3e-10 40.4 0.7 0.00022 21.7 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX32064.1 - 2.1e-08 34.7 0.2 3.5e-08 33.9 0.2 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX32064.1 - 5.1e-08 33.0 0.8 1.2e-07 31.9 0.7 1.7 1 1 0 1 1 1 1 Ankyrin repeats (many copies) SH3_9 PF14604.6 EKX32064.1 - 3.3e-06 26.9 0.8 1.7e-05 24.6 0.8 2.2 1 1 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EKX32064.1 - 4.2e-05 23.1 1.0 0.0012 18.4 1.0 2.8 1 1 0 1 1 1 1 SH3 domain Ank PF00023.30 EKX32064.1 - 0.00016 21.9 0.9 0.00044 20.6 0.9 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 EKX32064.1 - 0.00028 21.1 0.3 0.00095 19.4 0.2 2.0 2 0 0 2 2 2 1 Ankyrin repeat Solute_trans_a PF03619.16 EKX32065.1 - 6e-80 268.6 18.8 7e-80 268.3 18.8 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Ammonium_transp PF00909.21 EKX32066.1 - 3e-31 108.5 13.4 3e-31 108.5 13.4 2.3 2 0 0 2 2 2 2 Ammonium Transporter Family Zn_clus PF00172.18 EKX32068.1 - 2.4e-10 40.4 10.3 3.6e-10 39.8 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RWP-RK PF02042.15 EKX32069.1 - 1.1e-10 41.4 0.1 1.6e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain P22_AR_N PF10547.9 EKX32069.1 - 0.15 12.4 0.0 0.24 11.7 0.0 1.2 1 0 0 1 1 1 0 P22_AR N-terminal domain PhyH PF05721.13 EKX32070.1 - 9.2e-07 29.3 0.0 3e-06 27.6 0.0 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) FHA PF00498.26 EKX32071.1 - 1.8e-10 41.0 0.1 3.5e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 FHA domain zf-CRD PF17979.1 EKX32071.1 - 1.7e-09 38.0 13.2 1.7e-09 38.0 13.2 3.0 1 1 1 2 2 1 1 Cysteine rich domain with multizinc binding regions zf-C3HC4 PF00097.25 EKX32071.1 - 7.5e-06 25.7 8.3 7.5e-06 25.7 8.3 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EKX32071.1 - 2.1e-05 24.3 6.6 2.1e-05 24.3 6.6 3.0 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX32071.1 - 0.00078 19.4 6.8 0.00078 19.4 6.8 3.1 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EKX32071.1 - 0.00089 19.2 9.3 0.00089 19.2 9.3 3.4 2 1 1 3 3 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EKX32071.1 - 0.0014 18.4 9.9 0.0014 18.4 9.9 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX32071.1 - 0.0016 18.7 9.5 0.0016 18.7 9.5 3.2 3 1 0 3 3 2 1 Ring finger domain Yop-YscD_cpl PF16697.5 EKX32071.1 - 0.0024 18.2 0.0 0.14 12.5 0.0 2.3 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_4 PF15227.6 EKX32071.1 - 0.011 15.9 11.2 0.011 15.9 11.2 3.2 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING Integrin_B_tail PF07965.12 EKX32071.1 - 0.016 15.6 2.4 0.016 15.6 2.4 2.6 2 0 0 2 2 2 0 Integrin beta tail domain zf-RING_10 PF16685.5 EKX32071.1 - 6.4 7.0 12.4 1.4 9.1 5.0 2.7 2 0 0 2 2 2 0 zinc RING finger of MSL2 Rhodanese PF00581.20 EKX32072.1 - 2.2e-05 24.9 0.0 3.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Resolvase PF00239.21 EKX32072.1 - 0.17 12.0 0.1 0.3 11.2 0.1 1.5 1 0 0 1 1 1 0 Resolvase, N terminal domain Epimerase PF01370.21 EKX32073.1 - 2.1e-10 40.5 0.0 2.9e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EKX32073.1 - 1.2e-05 24.9 0.0 2.2e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase UDPG_MGDP_dh_N PF03721.14 EKX32073.1 - 0.0021 17.7 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain LRR_8 PF13855.6 EKX32074.1 - 3.6e-62 206.0 41.1 5.1e-17 61.4 3.6 7.5 3 2 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 EKX32074.1 - 2.6e-26 91.2 44.1 3.5e-06 27.2 1.3 8.4 2 2 7 9 9 9 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX32074.1 - 4.6e-17 62.2 0.0 6.2e-07 29.4 0.0 3.2 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EKX32074.1 - 5.5e-12 44.5 38.3 0.43 11.3 0.1 11.9 11 1 1 12 12 12 4 Leucine Rich Repeat GIT_SHD PF08518.11 EKX32074.1 - 1.3e-08 34.3 0.0 8.4 6.1 0.0 9.6 12 0 0 12 12 12 1 Spa2 homology domain (SHD) of GIT DUF5361 PF17318.2 EKX32074.1 - 4.1e-07 30.1 0.1 2.6 8.3 0.0 5.3 5 3 3 8 8 8 3 Family of unknown function (DUF5361) Rv2175c_C PF18367.1 EKX32074.1 - 3.8e-06 26.9 0.9 1.3 9.1 0.0 3.7 2 1 1 3 3 3 3 Rv2175c C-terminal domain of unknown function LRR_9 PF14580.6 EKX32074.1 - 4.3e-06 26.3 6.6 3.3 7.2 0.1 4.5 1 1 4 5 5 5 3 Leucine-rich repeat Adaptin_N PF01602.20 EKX32076.1 - 1.4e-106 357.2 5.1 2e-72 244.5 7.3 2.1 2 0 0 2 2 2 2 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EKX32076.1 - 2.9e-25 88.7 3.2 2.9e-25 88.7 3.2 1.7 2 0 0 2 2 2 1 Adaptin C-terminal domain Cnd1 PF12717.7 EKX32076.1 - 0.00014 22.0 4.3 0.24 11.4 0.1 3.3 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EKX32076.1 - 0.29 11.7 1.9 7.6 7.2 0.0 4.4 4 1 0 4 4 4 0 HEAT-like repeat TIG PF01833.24 EKX32077.1 - 0.0019 18.2 0.1 0.013 15.5 0.0 2.5 2 0 0 2 2 2 1 IPT/TIG domain Endonuclease_5 PF04493.14 EKX32078.1 - 6.8e-35 120.5 0.0 7.6e-35 120.4 0.0 1.0 1 0 0 1 1 1 1 Endonuclease V DUF4538 PF15061.6 EKX32080.1 - 0.088 12.6 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) Phlebovirus_G1 PF07243.11 EKX32081.1 - 0.31 9.3 1.9 0.44 8.9 1.9 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 RPW8 PF05659.11 EKX32082.1 - 0.17 11.5 2.4 1.6 8.4 0.3 2.5 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Hemerythrin PF01814.23 EKX32082.1 - 0.47 11.1 3.2 17 6.0 0.1 2.7 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain TPR_2 PF07719.17 EKX32083.1 - 0.00052 19.9 1.8 0.00096 19.1 1.8 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX32083.1 - 0.0031 17.8 0.1 0.0067 16.7 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX32083.1 - 0.017 15.3 0.6 0.036 14.3 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 EKX32083.1 - 0.11 12.6 2.5 0.18 11.8 2.5 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 EKX32083.1 - 0.17 11.8 3.5 0.29 11.0 3.5 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat C2 PF00168.30 EKX32086.1 - 2.1e-07 31.2 0.0 4.4e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain Copine PF07002.16 EKX32086.1 - 0.023 14.1 0.1 0.037 13.5 0.1 1.3 1 0 0 1 1 1 0 Copine zf-RING_12 PF17976.1 EKX32086.1 - 0.15 12.3 0.1 7.1 7.0 0.0 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Copine PF07002.16 EKX32087.1 - 4.9e-29 101.3 0.0 5.4e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 EKX32087.1 - 0.00019 21.6 0.0 0.00019 21.6 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus CUB_2 PF02408.20 EKX32088.1 - 0.016 14.9 0.3 0.024 14.4 0.3 1.3 1 0 0 1 1 1 0 CUB-like domain LSDAT_euk PF18139.1 EKX32089.1 - 2.5e-37 128.7 0.1 1.4e-36 126.3 0.1 2.1 1 1 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 EKX32089.1 - 8.2e-16 57.8 0.0 5.6e-09 35.5 0.0 3.2 2 1 0 2 2 2 2 SLOG in TRPM, prokaryote Ion_trans PF00520.31 EKX32089.1 - 0.00049 19.4 6.2 0.00095 18.5 6.2 1.4 1 0 0 1 1 1 1 Ion transport protein FAST_1 PF06743.15 EKX32089.1 - 0.028 14.3 7.9 2.3 8.2 0.1 4.8 4 1 1 5 5 5 0 FAST kinase-like protein, subdomain 1 FHIPEP PF00771.20 EKX32089.1 - 0.11 10.9 0.8 5.9 5.2 0.1 2.3 2 0 0 2 2 2 0 FHIPEP family Mito_carr PF00153.27 EKX32090.1 - 2.1e-32 110.9 0.2 1.5e-14 53.7 0.1 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein Myc_N PF01056.18 EKX32090.1 - 0.036 14.0 2.6 0.072 13.0 2.6 1.4 1 0 0 1 1 1 0 Myc amino-terminal region DUF3524 PF12038.8 EKX32090.1 - 0.14 12.0 0.0 9.9 5.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3524) TMEM215 PF15746.5 EKX32090.1 - 0.19 11.2 0.4 0.33 10.4 0.4 1.3 1 0 0 1 1 1 0 TMEM215 family Astro_capsid_p PF12226.8 EKX32090.1 - 0.43 9.7 3.6 0.69 9.0 3.6 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nucleo_P87 PF07267.11 EKX32090.1 - 5.4 5.7 7.5 0.13 11.1 1.0 1.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Imm48 PF15574.6 EKX32091.1 - 0.02 14.7 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 48 ZU5 PF00791.20 EKX32092.1 - 0.0023 18.3 0.0 0.0044 17.3 0.0 1.4 1 0 0 1 1 1 1 ZU5 domain RRM_1 PF00076.22 EKX32093.1 - 2.6e-16 59.2 0.0 2.8e-16 59.1 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 EKX32093.1 - 0.0027 17.7 0.1 0.011 15.7 0.1 1.8 1 1 0 1 1 1 1 RNA binding domain Raffinose_syn PF05691.12 EKX32094.1 - 1.9e-176 588.1 0.0 2.5e-176 587.7 0.0 1.0 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 LapA_dom PF06305.11 EKX32097.1 - 0.0072 16.1 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain MWFE PF15879.5 EKX32097.1 - 0.029 14.6 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase MWFE subunit UPF0767 PF15990.5 EKX32097.1 - 0.033 14.3 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 UPF0767 family Tad PF13400.6 EKX32097.1 - 0.07 13.4 1.0 0.24 11.7 0.3 1.9 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like LysM PF01476.20 EKX32098.1 - 2e-13 50.1 0.1 9.5e-08 32.0 0.0 3.1 3 0 0 3 3 3 2 LysM domain HTH_28 PF13518.6 EKX32098.1 - 0.095 12.8 0.0 5.2 7.3 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain tRNA-synt_1g PF09334.11 EKX32099.1 - 0.034 12.9 0.3 0.045 12.5 0.3 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (M) PDEase_I PF00233.19 EKX32100.1 - 1.1e-44 153.0 3.1 3.4e-30 105.5 0.1 3.0 2 1 1 3 3 3 2 3'5'-cyclic nucleotide phosphodiesterase Flu_NS2 PF00601.19 EKX32100.1 - 0.0075 16.6 0.8 0.0075 16.6 0.8 2.3 2 0 0 2 2 2 1 Influenza non-structural protein (NS2) HD PF01966.22 EKX32100.1 - 0.03 14.5 0.0 0.069 13.4 0.0 1.7 1 0 0 1 1 1 0 HD domain META PF03724.16 EKX32100.1 - 0.041 13.9 0.0 0.088 12.8 0.0 1.5 1 0 0 1 1 1 0 META domain TPR_12 PF13424.6 EKX32100.1 - 0.099 13.0 0.0 0.6 10.4 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_11 PF13086.6 EKX32104.1 - 0.086 12.6 4.6 0.14 11.9 4.6 1.3 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 EKX32104.1 - 8.4 5.9 7.4 12 5.4 7.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit SpoIIIAH PF12685.7 EKX32105.1 - 0.064 13.1 2.0 0.069 13.0 2.0 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Nop14 PF04147.12 EKX32105.1 - 0.13 10.4 31.2 0.16 10.2 31.2 1.0 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.16 EKX32105.1 - 4.4 6.4 15.3 6.2 5.9 15.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FXa_inhibition PF14670.6 EKX32106.1 - 9.7 6.6 10.8 2.6 8.4 0.1 3.4 3 0 0 3 3 3 0 Coagulation Factor Xa inhibitory site Lebercilin PF15619.6 EKX32109.1 - 1.3e-08 34.8 51.0 0.00092 18.9 10.6 3.1 3 0 0 3 3 3 3 Ciliary protein causing Leber congenital amaurosis disease WEMBL PF05701.11 EKX32109.1 - 0.00059 18.7 37.8 0.0014 17.4 19.1 3.1 2 1 1 3 3 3 2 Weak chloroplast movement under blue light DegS PF05384.11 EKX32109.1 - 0.0024 17.4 6.4 0.0024 17.4 6.4 5.3 3 2 4 7 7 6 2 Sensor protein DegS DnaJ PF00226.31 EKX32109.1 - 0.005 16.9 0.1 0.077 13.1 0.0 2.8 2 0 0 2 2 2 1 DnaJ domain MAD PF05557.13 EKX32109.1 - 0.0073 14.7 38.9 0.041 12.2 2.6 2.2 2 0 0 2 2 2 2 Mitotic checkpoint protein MscS_porin PF12795.7 EKX32109.1 - 0.012 15.2 36.2 0.072 12.6 12.7 3.3 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain CENP-F_leu_zip PF10473.9 EKX32109.1 - 0.013 15.6 45.9 0.18 11.8 16.7 4.1 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BST2 PF16716.5 EKX32109.1 - 0.015 15.8 2.4 0.015 15.8 2.4 4.4 2 1 3 5 5 5 0 Bone marrow stromal antigen 2 Tropomyosin_1 PF12718.7 EKX32109.1 - 0.023 14.9 16.2 0.023 14.9 16.2 3.9 2 1 0 3 3 3 0 Tropomyosin like Spc7 PF08317.11 EKX32109.1 - 0.025 13.5 44.2 0.02 13.8 2.7 3.3 2 1 1 3 3 3 0 Spc7 kinetochore protein AAA_13 PF13166.6 EKX32109.1 - 0.064 11.9 39.0 0.035 12.8 25.1 2.2 1 1 1 2 2 2 0 AAA domain HMMR_N PF15905.5 EKX32109.1 - 0.093 12.2 42.5 1.1 8.7 11.1 3.2 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Tropomyosin PF00261.20 EKX32109.1 - 0.11 11.8 46.3 1.5 8.1 4.5 4.9 2 1 2 4 4 4 0 Tropomyosin Myosin_tail_1 PF01576.19 EKX32109.1 - 0.19 9.5 46.1 1 7.1 46.1 2.0 1 1 0 1 1 1 0 Myosin tail Laminin_II PF06009.12 EKX32109.1 - 0.27 11.3 33.5 0.89 9.6 10.4 5.3 3 2 2 5 5 5 0 Laminin Domain II Seryl_tRNA_N PF02403.22 EKX32109.1 - 0.3 11.3 41.1 1.5 9.1 12.8 4.4 2 2 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 EKX32109.1 - 0.56 10.2 28.7 1.2 9.2 5.4 4.6 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) EzrA PF06160.12 EKX32109.1 - 0.88 7.7 40.0 0.037 12.2 14.1 3.3 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA HrpB7 PF09486.10 EKX32109.1 - 0.89 9.9 33.7 15 5.9 17.5 5.3 3 2 1 4 4 4 0 Bacterial type III secretion protein (HrpB7) TPR_MLP1_2 PF07926.12 EKX32109.1 - 1.1 9.4 48.3 0.097 12.7 21.0 4.7 2 2 2 4 4 4 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 EKX32109.1 - 1.2 9.3 45.0 0.58 10.4 4.1 3.4 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 EKX32109.1 - 1.3 9.5 31.1 3.6 8.1 2.7 5.8 3 1 3 6 6 6 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.10 EKX32109.1 - 1.4 9.1 33.1 0.51 10.5 5.2 3.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 EKX32109.1 - 1.7 9.1 40.2 4.4 7.7 3.2 3.3 1 1 2 3 3 3 0 Fez1 Atg14 PF10186.9 EKX32109.1 - 1.8 7.6 37.7 0.092 11.8 2.3 3.2 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 EKX32109.1 - 1.9 7.8 27.1 1.9 7.8 18.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF724 PF05266.14 EKX32109.1 - 3.6 7.4 41.9 0.14 12.0 2.1 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF724) Golgin_A5 PF09787.9 EKX32109.1 - 3.8 6.9 42.3 0.12 11.9 3.2 3.1 2 1 1 3 3 3 0 Golgin subfamily A member 5 TMPIT PF07851.13 EKX32109.1 - 4.5 6.4 34.4 0.5 9.6 2.3 3.2 2 1 1 3 3 3 0 TMPIT-like protein YliH PF10799.8 EKX32109.1 - 5.6 6.9 10.4 0.13 12.2 1.5 2.8 3 1 0 3 3 3 0 Biofilm formation protein (YliH/bssR) DUF4434 PF14488.6 EKX32110.1 - 0.043 13.8 0.0 0.049 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Ig_6 PF18452.1 EKX32112.1 - 0.071 12.7 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 Immunoglobulin domain DUF1451 PF07295.11 EKX32115.1 - 0.005 16.9 0.2 0.0066 16.5 0.2 1.2 1 0 0 1 1 1 1 Zinc-ribbon containing domain Atrophin-1 PF03154.15 EKX32115.1 - 0.062 11.6 1.2 0.075 11.3 1.2 1.0 1 0 0 1 1 1 0 Atrophin-1 family Med8 PF10232.9 EKX32115.1 - 0.078 12.6 0.1 0.093 12.3 0.1 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 ScsC_N PF18312.1 EKX32115.1 - 0.12 12.2 0.0 56 3.7 0.0 3.4 3 0 0 3 3 3 0 Copper resistance protein ScsC N-terminal domain Terminase_4 PF05119.12 EKX32115.1 - 0.13 12.7 1.5 0.32 11.5 1.4 1.7 1 1 0 1 1 1 0 Phage terminase, small subunit YtxH PF12732.7 EKX32115.1 - 0.53 10.8 5.0 0.94 10.1 5.1 1.4 1 1 0 1 1 1 0 YtxH-like protein DUF3402 PF11882.8 EKX32116.1 - 0.0084 15.3 1.4 0.01 15.0 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) Caskin-tail PF16632.5 EKX32116.1 - 0.13 12.7 0.6 0.29 11.5 0.6 1.5 1 0 0 1 1 1 0 C-terminal region of Caskin API5 PF05918.11 EKX32116.1 - 0.9 8.3 11.1 1.2 7.9 11.1 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Ribosomal_L27e PF01777.18 EKX32117.1 - 0.023 15.1 1.4 0.037 14.4 0.2 2.0 2 0 0 2 2 2 0 Ribosomal L27e protein family DUF2829 PF11195.8 EKX32117.1 - 0.32 11.3 0.1 0.32 11.3 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2829) SIR4_SID PF16991.5 EKX32120.1 - 1.2 9.1 7.2 1.3 9.0 3.5 2.2 2 0 0 2 2 2 0 Sir4 SID domain YtxH PF12732.7 EKX32121.1 - 0.02 15.4 1.0 0.18 12.4 1.0 2.1 1 1 0 1 1 1 0 YtxH-like protein DDE_Tnp_ISL3 PF01610.17 EKX32121.1 - 0.088 12.5 0.0 0.13 12.0 0.0 1.3 1 1 0 1 1 1 0 Transposase Herpes_UL92 PF03048.14 EKX32124.1 - 1.2e-07 31.7 0.3 3.2e-07 30.3 0.3 1.7 1 0 0 1 1 1 1 UL92 family HR1 PF02185.16 EKX32124.1 - 0.021 14.9 1.5 1.5 9.0 0.2 3.1 2 1 1 3 3 3 0 Hr1 repeat C2 PF00168.30 EKX32126.1 - 8.3e-13 48.5 0.4 2.1e-12 47.2 0.4 1.7 1 1 0 1 1 1 1 C2 domain UNC-93 PF05978.16 EKX32126.1 - 0.00097 18.9 1.9 0.0018 18.0 1.9 1.4 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Mt_ATP-synt_B PF05405.14 EKX32126.1 - 0.18 11.4 6.3 0.53 9.9 6.2 1.9 1 1 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) PutA_N PF18083.1 EKX32126.1 - 3.1 7.8 6.8 78 3.3 0.4 3.8 3 1 2 5 5 5 0 Proline utilization A N-terminal domain TRM PF02005.16 EKX32127.1 - 3.8e-88 296.2 0.0 4.6e-88 295.9 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Lipase PF00151.19 EKX32127.1 - 0.14 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipase PrmA PF06325.13 EKX32127.1 - 0.15 11.4 0.3 0.26 10.6 0.3 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PRKCSH PF07915.13 EKX32128.1 - 1.6e-25 89.9 8.5 7.1e-12 46.2 0.1 3.2 2 1 0 2 2 2 2 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 EKX32128.1 - 6.3e-16 58.4 0.4 1.5e-08 34.5 0.0 2.2 1 1 1 2 2 2 2 Glucosidase II beta subunit-like protein ATG27 PF09451.10 EKX32128.1 - 0.0098 15.8 0.3 0.1 12.4 0.0 2.2 2 0 0 2 2 2 1 Autophagy-related protein 27 IPK PF03770.16 EKX32129.1 - 1e-16 61.4 0.1 2e-16 60.4 0.1 1.5 1 0 0 1 1 1 1 Inositol polyphosphate kinase EF-hand_1 PF00036.32 EKX32130.1 - 4.7e-15 53.9 3.2 7.9e-06 25.1 0.2 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EKX32130.1 - 5.5e-15 54.0 3.0 1.6e-06 27.6 0.5 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 EKX32130.1 - 2.5e-11 43.8 3.1 0.00011 22.6 0.2 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX32130.1 - 1.9e-09 36.6 1.1 0.00037 19.9 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX32130.1 - 2.3e-07 30.6 6.8 0.028 14.3 0.4 4.1 2 2 2 4 4 4 3 EF-hand domain pair SWI2_SNF2 PF18766.1 EKX32130.1 - 0.13 11.9 1.2 0.26 10.9 1.2 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase SPARC_Ca_bdg PF10591.9 EKX32130.1 - 3.2 8.1 7.6 0.52 10.6 0.1 2.9 3 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region MAS20 PF02064.15 EKX32130.1 - 8.2 6.5 8.2 4.8 7.3 0.0 3.1 3 0 0 3 3 3 0 MAS20 protein import receptor XRN_N PF03159.18 EKX32131.1 - 2.1e-30 105.9 0.0 1e-15 57.9 0.0 2.4 1 1 1 2 2 2 2 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 EKX32131.1 - 3.2e-07 29.7 0.3 8.9e-06 24.9 0.0 2.2 2 0 0 2 2 2 2 Xrn1 helical domain HTH_Tnp_Tc5 PF03221.16 EKX32134.1 - 0.00016 21.6 0.0 0.00039 20.4 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF945 PF06097.11 EKX32134.1 - 0.012 14.7 0.9 0.016 14.3 0.9 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) Troponin PF00992.20 EKX32135.1 - 0.1 12.9 1.6 2.4 8.5 0.1 2.1 1 1 1 2 2 2 0 Troponin CK_II_beta PF01214.18 EKX32136.1 - 0.051 13.4 0.7 0.093 12.5 0.7 1.3 1 0 0 1 1 1 0 Casein kinase II regulatory subunit ketoacyl-synt PF00109.26 EKX32138.1 - 1.1e-24 87.4 1.6 9.7e-17 61.4 0.6 2.1 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain MazE_antitoxin PF04014.18 EKX32138.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Antidote-toxin recognition MazE, bacterial antitoxin Nipped-B_C PF12830.7 EKX32138.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus DUF1281_C PF18406.1 EKX32141.1 - 0.066 12.9 0.8 0.14 11.8 0.8 1.6 1 0 0 1 1 1 0 Ferredoxin-like domain in Api92-like protein Ribosomal_L7Ae PF01248.26 EKX32142.1 - 2.8e-27 94.3 0.0 3.8e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 EKX32142.1 - 0.00023 21.0 0.0 0.0003 20.6 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 EKX32142.1 - 0.0098 15.9 0.0 0.011 15.8 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 DUF2207 PF09972.9 EKX32144.1 - 0.021 13.6 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PMP22_Claudin PF00822.20 EKX32144.1 - 0.68 9.8 7.7 0.043 13.7 2.3 1.8 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family Acetyltransf_1 PF00583.25 EKX32145.1 - 6.9e-14 52.1 0.0 9.9e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EKX32145.1 - 1.2e-09 38.1 0.0 2.1e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EKX32145.1 - 8.6e-08 32.5 0.0 1.3e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EKX32145.1 - 0.00018 21.4 0.0 0.00031 20.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EKX32145.1 - 0.00089 19.3 0.0 0.0017 18.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain SAM_1 PF00536.30 EKX32146.1 - 0.0007 20.0 0.0 0.0033 17.8 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SPRY PF00622.28 EKX32146.1 - 0.0032 17.6 0.0 0.012 15.8 0.0 1.9 1 1 0 1 1 1 1 SPRY domain TPR_MLP1_2 PF07926.12 EKX32146.1 - 3.2 7.8 0.0 3.2 7.8 0.0 3.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Mpv17_PMP22 PF04117.12 EKX32147.1 - 3.1e-07 30.5 0.3 8.4e-07 29.1 0.1 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family Arm PF00514.23 EKX32149.1 - 2.8e-07 30.4 1.6 0.88 9.7 0.0 5.9 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EKX32149.1 - 0.017 15.1 2.7 12 6.0 0.1 3.7 2 2 2 4 4 4 0 Spinocerebellar ataxia type 10 protein domain DUF3302 PF11742.8 EKX32149.1 - 0.21 11.8 0.7 5.9 7.1 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3302) Ank_4 PF13637.6 EKX32150.1 - 2.2e-12 47.3 3.8 1.2e-08 35.3 0.5 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX32150.1 - 3.8e-12 46.6 0.3 4.5e-12 46.4 0.3 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX32150.1 - 1.5e-09 38.0 1.7 0.0012 19.0 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX32150.1 - 1.2e-07 31.8 4.4 0.0029 18.0 0.3 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EKX32150.1 - 2.2e-07 30.6 0.7 0.043 14.4 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EKX32151.1 - 2.1e-09 37.5 0.0 6e-09 36.0 0.0 1.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX32151.1 - 4e-07 30.5 0.0 7.1e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX32151.1 - 8.5e-06 26.0 0.0 2.2e-05 24.7 0.0 1.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EKX32151.1 - 1.7e-05 24.8 0.0 6.3e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EKX32151.1 - 9e-05 23.0 0.0 0.0002 21.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) PilJ PF13675.6 EKX32152.1 - 0.048 13.7 0.3 5.5 7.0 0.1 2.8 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term VP4_haemagglut PF00426.18 EKX32152.1 - 0.087 13.0 0.2 0.31 11.2 0.1 2.0 2 0 0 2 2 2 0 Outer Capsid protein VP4 (Hemagglutinin) Concanavalin-like domain Fer4_24 PF18109.1 EKX32152.1 - 0.088 13.1 0.8 0.28 11.5 0.8 1.9 1 0 0 1 1 1 0 Ferredoxin I 4Fe-4S cluster domain DUF1664 PF07889.12 EKX32152.1 - 0.21 11.6 3.1 0.28 11.2 0.6 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) HisKA_3 PF07730.13 EKX32152.1 - 0.22 12.0 1.1 0.86 10.2 1.1 2.0 1 0 0 1 1 1 0 Histidine kinase Sipho_Gp157 PF05565.11 EKX32152.1 - 0.22 11.5 0.6 15 5.5 0.1 2.3 2 0 0 2 2 2 0 Siphovirus Gp157 Baculo_PEP_C PF04513.12 EKX32152.1 - 1.5 8.8 7.3 0.66 10.0 0.8 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus LsmAD PF06741.13 EKX32153.1 - 1.9e-13 50.7 0.9 1.9e-13 50.7 0.9 2.3 3 0 0 3 3 3 1 LsmAD domain SM-ATX PF14438.6 EKX32153.1 - 5.9e-12 45.6 0.0 1.2e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain PAM2 PF07145.15 EKX32153.1 - 0.00033 20.1 0.3 0.00033 20.1 0.3 2.3 2 0 0 2 2 2 1 Ataxin-2 C-terminal region Robl_LC7 PF03259.17 EKX32154.1 - 0.0092 15.7 4.1 0.4 10.5 1.7 2.4 2 1 0 2 2 2 2 Roadblock/LC7 domain MetallophosN PF16371.5 EKX32154.1 - 0.14 12.5 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 N terminal of Calcineurin-like phosphoesterase CarboxypepD_reg PF13620.6 EKX32154.1 - 0.16 12.3 0.1 0.61 10.4 0.0 1.8 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain Ribosomal_60s PF00428.19 EKX32154.1 - 0.69 10.5 14.5 1.5 9.5 12.3 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3138 PF11336.8 EKX32154.1 - 1.6 7.2 4.8 2.4 6.7 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) RNA_pol_Rpb5_C PF01191.19 EKX32155.1 - 2.2e-32 110.7 2.1 2.5e-32 110.6 2.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain Topo_Zn_Ribbon PF08272.11 EKX32155.1 - 0.16 11.6 0.0 0.8 9.4 0.0 2.0 2 0 0 2 2 2 0 Topoisomerase I zinc-ribbon-like Ion_trans PF00520.31 EKX32156.1 - 9.3e-19 67.6 12.0 7.4e-11 41.7 0.6 2.3 1 1 1 2 2 2 2 Ion transport protein PH PF00169.29 EKX32156.1 - 4.2e-07 30.4 0.2 5.6e-06 26.8 0.2 2.3 1 1 0 1 1 1 1 PH domain PH_4 PF15404.6 EKX32156.1 - 0.0035 17.2 0.0 0.0084 15.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain EF-hand_1 PF00036.32 EKX32156.1 - 0.014 14.9 0.0 0.052 13.1 0.0 2.1 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 EKX32156.1 - 0.024 14.6 0.1 0.079 12.9 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain YlqD PF11068.8 EKX32156.1 - 0.062 13.7 0.0 0.22 11.9 0.0 1.9 1 0 0 1 1 1 0 YlqD protein EF-hand_7 PF13499.6 EKX32156.1 - 0.09 13.2 0.1 0.31 11.5 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain pair DUF773 PF05600.12 EKX32156.1 - 0.11 11.2 0.2 0.27 9.9 0.0 1.6 2 0 0 2 2 2 0 CDK5 regulatory subunit-associated protein 3 FANCI_HD2 PF14680.6 EKX32156.1 - 0.18 11.0 1.0 0.35 10.1 0.5 1.7 2 0 0 2 2 2 0 FANCI helical domain 2 BNIP3 PF06553.12 EKX32156.1 - 0.57 9.8 4.0 1.5 8.5 4.0 1.6 1 0 0 1 1 1 0 BNIP3 PKD_channel PF08016.12 EKX32156.1 - 1.5 7.4 7.8 0.45 9.1 0.2 2.2 1 1 1 2 2 2 0 Polycystin cation channel FUSC PF04632.12 EKX32157.1 - 0.00096 17.8 3.3 0.0011 17.7 0.8 1.8 1 1 1 2 2 2 2 Fusaric acid resistance protein family Cytochrom_C_2 PF01322.20 EKX32157.1 - 0.0021 18.9 0.2 0.056 14.3 0.0 2.3 2 1 0 2 2 2 1 Cytochrome C' NPV_P10 PF05531.12 EKX32157.1 - 0.0035 17.8 4.2 1.2 9.7 0.3 3.4 3 0 0 3 3 3 1 Nucleopolyhedrovirus P10 protein CCDC142 PF14923.6 EKX32157.1 - 0.021 13.6 0.5 0.027 13.2 0.5 1.2 1 0 0 1 1 1 0 Coiled-coil protein 142 Jnk-SapK_ap_N PF09744.9 EKX32157.1 - 0.046 14.0 0.5 0.046 14.0 0.5 2.5 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF4482 PF14818.6 EKX32157.1 - 0.1 13.4 8.8 0.034 15.0 2.2 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4482) Cytochrom_B562 PF07361.11 EKX32157.1 - 0.14 12.9 0.6 5.7 7.7 0.1 2.7 2 1 1 3 3 3 0 Cytochrome b562 Vps5 PF09325.10 EKX32157.1 - 0.15 11.6 7.3 0.3 10.6 0.9 2.5 2 1 0 2 2 2 0 Vps5 C terminal like LPP PF04728.13 EKX32157.1 - 0.25 11.8 6.7 0.84 10.1 0.8 2.8 2 1 0 2 2 2 0 Lipoprotein leucine-zipper Peptidase_M61 PF05299.12 EKX32157.1 - 0.29 11.5 3.2 15 6.0 0.3 2.4 2 0 0 2 2 2 0 M61 glycyl aminopeptidase FapA PF03961.13 EKX32157.1 - 0.32 9.6 7.1 1.9 7.0 0.2 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A CorA PF01544.18 EKX32157.1 - 0.35 10.1 7.4 1.8 7.8 0.8 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein RecG_N PF17190.4 EKX32157.1 - 0.41 11.4 4.9 13 6.6 0.6 2.9 2 1 1 3 3 3 0 RecG N-terminal helical domain YlbD_coat PF14071.6 EKX32157.1 - 0.43 10.8 5.3 1.1 9.5 0.2 3.0 2 2 1 3 3 3 0 Putative coat protein V_ATPase_I PF01496.19 EKX32157.1 - 0.45 8.4 8.1 0.79 7.6 1.1 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Cob_adeno_trans PF01923.18 EKX32157.1 - 0.56 10.3 3.9 0.82 9.8 1.5 2.3 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Spore_III_AB PF09548.10 EKX32157.1 - 0.6 10.2 3.9 0.85 9.7 0.9 2.1 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) BLOC1_2 PF10046.9 EKX32157.1 - 0.6 10.4 7.9 3 8.2 1.6 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PI_PP_I PF18363.1 EKX32157.1 - 0.61 10.3 4.9 0.42 10.8 1.2 2.3 2 1 0 2 2 2 0 Phosphoinositide phosphatase insertion domain YgaB PF14182.6 EKX32157.1 - 0.71 10.3 7.5 0.8 10.1 0.5 2.9 2 2 0 2 2 2 0 YgaB-like protein Seryl_tRNA_N PF02403.22 EKX32157.1 - 0.72 10.1 10.3 0.56 10.5 2.0 2.6 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.10 EKX32157.1 - 1 9.5 11.2 2.2 8.5 1.5 2.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 EKX32157.1 - 1.5 9.5 8.8 2.7 8.7 0.6 3.3 2 2 0 2 2 2 0 SlyX YscO PF07321.12 EKX32157.1 - 1.7 8.6 8.1 2.4 8.1 1.3 2.4 2 1 0 2 2 2 0 Type III secretion protein YscO Occludin_ELL PF07303.13 EKX32157.1 - 1.8 9.4 6.7 7.7 7.3 0.6 2.8 2 2 0 2 2 2 0 Occludin homology domain TMPIT PF07851.13 EKX32157.1 - 2.3 7.4 8.2 1.9 7.7 0.6 2.4 2 1 1 3 3 3 0 TMPIT-like protein Lebercilin PF15619.6 EKX32157.1 - 2.5 7.7 14.7 2.8 7.6 8.3 2.6 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease MCU PF04678.13 EKX32157.1 - 2.8 8.0 6.1 26 4.9 6.1 2.1 1 1 0 1 1 1 0 Mitochondrial calcium uniporter GAS PF13851.6 EKX32157.1 - 4.3 6.6 13.6 1.2 8.4 6.1 2.5 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding KxDL PF10241.9 EKX32157.1 - 10 6.5 12.4 5.6 7.3 1.4 3.0 3 1 0 3 3 2 0 Uncharacterized conserved protein SOUL PF04832.12 EKX32158.1 - 7e-19 68.6 0.1 7.6e-17 62.0 0.1 2.2 1 1 0 1 1 1 1 SOUL heme-binding protein Yae1_N PF09811.9 EKX32158.1 - 0.28 10.9 4.9 0.26 11.0 2.4 2.2 2 0 0 2 2 2 0 Essential protein Yae1, N terminal zf-C3HC4_3 PF13920.6 EKX32163.1 - 0.0036 17.1 28.3 0.025 14.4 17.1 2.6 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 EKX32163.1 - 0.037 13.9 4.3 4.6 7.2 0.1 3.0 2 0 0 2 2 2 0 Rad50 zinc hook motif zinc-ribbons_6 PF07191.12 EKX32163.1 - 0.24 11.4 22.6 0.17 11.9 2.4 2.5 1 1 1 2 2 2 0 zinc-ribbons ArAE_1_C PF11728.8 EKX32164.1 - 0.12 12.4 0.9 0.31 11.0 0.1 2.0 2 0 0 2 2 2 0 Putative aromatic acid exporter C-terminal domain zf-CCHC PF00098.23 EKX32165.1 - 2.1e-17 62.3 23.3 1.3e-07 31.3 1.7 3.1 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.6 EKX32165.1 - 9.1e-06 25.5 17.1 0.0091 15.9 3.4 3.1 1 1 2 3 3 3 3 Zinc knuckle zf-CCHC_5 PF14787.6 EKX32165.1 - 1.2e-05 24.9 15.8 0.0092 15.7 1.1 3.1 3 0 0 3 3 3 3 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 EKX32165.1 - 0.00021 21.0 6.1 0.0042 16.9 0.6 3.2 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_4 PF14392.6 EKX32165.1 - 0.0012 18.5 16.2 0.62 9.8 1.5 3.1 3 0 0 3 3 3 3 Zinc knuckle YhfH PF14149.6 EKX32165.1 - 0.081 12.9 0.2 0.081 12.9 0.2 3.1 3 0 0 3 3 3 0 YhfH-like protein DZR PF12773.7 EKX32165.1 - 0.24 11.5 12.2 0.043 13.8 5.9 2.5 2 1 0 2 2 2 0 Double zinc ribbon PHD PF00628.29 EKX32165.1 - 0.74 9.7 11.2 15 5.6 4.3 3.0 1 1 2 3 3 3 0 PHD-finger zf-ribbon_3 PF13248.6 EKX32165.1 - 2.7 7.5 10.9 6 6.4 0.5 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Prok-RING_2 PF14445.6 EKX32165.1 - 3.5 7.9 9.3 1.1 9.5 1.4 2.6 1 1 2 3 3 3 0 Prokaryotic RING finger family 2 Anti-TRAP PF15777.5 EKX32165.1 - 4.8 7.2 7.9 4.7 7.3 2.4 2.4 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein EF-hand_7 PF13499.6 EKX32167.1 - 5.3e-27 94.1 14.9 1.4e-09 38.3 3.7 4.1 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 EKX32167.1 - 6.8e-20 69.1 19.5 6.3e-05 22.2 0.6 6.7 6 0 0 6 6 6 4 EF hand EF-hand_6 PF13405.6 EKX32167.1 - 1.7e-17 61.8 18.4 6.6e-06 25.6 0.2 7.4 7 0 0 7 7 7 5 EF-hand domain EF-hand_8 PF13833.6 EKX32167.1 - 2.7e-10 39.9 11.8 0.00014 21.6 2.1 5.1 4 0 0 4 4 4 2 EF-hand domain pair cNMP_binding PF00027.29 EKX32167.1 - 7.3e-08 32.4 0.0 1.8e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain EF-hand_9 PF14658.6 EKX32167.1 - 1.4e-06 28.6 2.1 0.0012 19.1 0.2 3.6 5 0 0 5 5 4 2 EF-hand domain EF-hand_5 PF13202.6 EKX32167.1 - 2.4e-06 26.8 22.5 0.07 12.7 0.5 6.6 6 0 0 6 6 6 3 EF hand EF-hand_4 PF12763.7 EKX32167.1 - 5.4e-06 26.3 7.6 0.35 10.8 0.3 5.3 5 1 1 6 6 6 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EKX32167.1 - 0.00039 20.7 9.7 0.86 9.9 0.4 4.9 4 1 0 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region Sugarporin_N PF11471.8 EKX32167.1 - 0.034 14.1 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension DUF1456 PF07308.13 EKX32167.1 - 0.047 14.0 0.8 24 5.3 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1456) DegT_DnrJ_EryC1 PF01041.17 EKX32168.1 - 1.3e-31 110.3 0.0 3.6e-29 102.2 0.0 2.8 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EKX32168.1 - 9.3e-06 25.0 0.0 1.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EKX32168.1 - 0.01 14.8 0.0 0.018 14.0 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V MTTB PF06253.11 EKX32168.1 - 0.52 8.2 1.6 0.42 8.5 0.0 1.5 2 0 0 2 2 2 0 Trimethylamine methyltransferase (MTTB) DEAD PF00270.29 EKX32169.1 - 1.4e-49 168.2 0.0 2.6e-49 167.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX32169.1 - 2.7e-19 69.6 0.0 1.3e-17 64.1 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 EKX32169.1 - 2.8e-11 43.5 6.4 1.3e-10 41.4 6.4 2.2 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.15 EKX32169.1 - 1.2e-07 31.9 0.0 4.5e-07 30.0 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TilS_C PF11734.8 EKX32169.1 - 0.12 11.8 1.2 1.4 8.4 0.0 2.5 2 0 0 2 2 2 0 TilS substrate C-terminal domain Exonuc_VII_S PF02609.16 EKX32169.1 - 0.53 10.4 4.7 0.91 9.6 0.3 3.1 3 0 0 3 3 3 0 Exonuclease VII small subunit Rubis-subs-bind PF09273.11 EKX32170.1 - 6.9e-17 62.4 0.0 1.4e-16 61.3 0.0 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 EKX32170.1 - 0.009 16.4 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 1 SET domain dUTPase_2 PF08761.11 EKX32170.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 dUTPase C2 PF00168.30 EKX32171.1 - 6e-17 61.8 0.0 1.1e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain TPR_2 PF07719.17 EKX32171.1 - 0.0078 16.2 5.0 0.17 12.1 0.9 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat Collagen PF01391.18 EKX32171.1 - 0.15 11.8 8.3 0.31 10.8 8.3 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Coatomer_WDAD PF04053.14 EKX32171.1 - 0.24 10.4 0.4 0.45 9.5 0.4 1.3 1 0 0 1 1 1 0 Coatomer WD associated region TPR_12 PF13424.6 EKX32171.1 - 5.7 7.3 11.9 1.1 9.6 5.6 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX32172.1 - 0.97 9.4 6.8 0.67 9.9 0.4 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat cNMP_binding PF00027.29 EKX32173.1 - 7.1e-08 32.4 0.0 2.6e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Pepsin-I3 PF06394.13 EKX32174.1 - 8 6.7 6.9 4.3 7.6 0.2 2.9 3 0 0 3 3 3 0 Pepsin inhibitor-3-like repeated domain Kinesin PF00225.23 EKX32175.1 - 3.9e-82 275.8 0.0 1e-81 274.5 0.0 1.6 1 1 1 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EKX32175.1 - 2.6e-20 72.9 0.0 5.7e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Med22 PF06179.12 EKX32175.1 - 0.036 14.3 2.6 0.058 13.6 1.5 1.9 2 0 0 2 2 2 0 Surfeit locus protein 5 subunit 22 of Mediator complex FDF PF09532.10 EKX32175.1 - 0.14 13.0 0.2 0.32 11.9 0.2 1.6 1 0 0 1 1 1 0 FDF domain YabA PF06156.13 EKX32175.1 - 0.38 11.4 5.8 0.48 11.1 2.8 2.5 1 1 1 2 2 2 0 Initiation control protein YabA AAA_23 PF13476.6 EKX32175.1 - 5.6 7.4 7.4 11 6.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain RVT_1 PF00078.27 EKX32180.1 - 2.6e-09 36.9 0.0 9.2e-06 25.3 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) ORC5_C PF14630.6 EKX32180.1 - 0.0067 16.0 0.1 0.0084 15.7 0.1 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus Actin PF00022.19 EKX32181.1 - 9.6e-98 327.4 0.0 3.7e-97 325.5 0.0 1.7 1 1 0 1 1 1 1 Actin APG6_N PF17675.1 EKX32182.1 - 8.3e-05 23.1 13.9 0.0001 22.8 13.9 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region ERM PF00769.19 EKX32182.1 - 0.00077 19.4 14.9 0.00088 19.2 14.9 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family HAUS-augmin3 PF14932.6 EKX32182.1 - 0.00097 18.8 13.7 0.0012 18.5 13.7 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 FapA PF03961.13 EKX32182.1 - 0.0046 15.6 11.6 0.0052 15.5 11.6 1.0 1 0 0 1 1 1 1 Flagellar Assembly Protein A DUF4201 PF13870.6 EKX32182.1 - 0.007 16.1 13.5 0.0083 15.9 13.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Uso1_p115_C PF04871.13 EKX32182.1 - 0.0078 16.6 15.6 0.011 16.1 15.6 1.2 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region DUF724 PF05266.14 EKX32182.1 - 0.0087 15.9 11.1 0.01 15.7 11.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF724) ISG65-75 PF11727.8 EKX32182.1 - 0.011 15.0 6.7 0.013 14.8 6.7 1.0 1 0 0 1 1 1 0 Invariant surface glycoprotein RILP PF11461.8 EKX32182.1 - 0.015 15.5 10.2 0.061 13.5 2.1 2.3 1 1 1 2 2 2 0 Rab interacting lysosomal protein Herpes_UL6 PF01763.16 EKX32182.1 - 0.016 13.8 8.3 0.018 13.6 8.3 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like XRCC4 PF06632.12 EKX32182.1 - 0.02 13.8 6.9 0.021 13.7 6.9 1.0 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3584 PF12128.8 EKX32182.1 - 0.025 12.1 12.5 0.028 12.0 12.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4226 PF10774.9 EKX32182.1 - 0.026 14.8 5.2 0.04 14.2 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) Chordopox_A30L PF06015.12 EKX32182.1 - 0.032 14.0 2.6 0.061 13.2 2.6 1.5 1 0 0 1 1 1 0 Chordopoxvirus A30L protein HIP1_clath_bdg PF16515.5 EKX32182.1 - 0.035 14.7 15.3 0.67 10.6 5.3 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 HemX PF04375.14 EKX32182.1 - 0.036 13.4 10.8 0.042 13.1 10.8 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Spc7 PF08317.11 EKX32182.1 - 0.068 12.1 12.5 0.089 11.7 12.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4337 PF14235.6 EKX32182.1 - 0.075 13.1 6.4 0.1 12.7 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Jnk-SapK_ap_N PF09744.9 EKX32182.1 - 0.086 13.1 14.8 0.1 12.8 14.8 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 WD40_alt PF14077.6 EKX32182.1 - 0.13 12.1 4.1 2.4 8.1 0.6 2.6 2 0 0 2 2 2 0 Alternative WD40 repeat motif V_ATPase_I PF01496.19 EKX32182.1 - 0.17 9.8 7.6 0.18 9.7 7.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PCRF PF03462.18 EKX32182.1 - 0.18 11.6 8.3 0.22 11.4 8.3 1.1 1 0 0 1 1 1 0 PCRF domain CENP-H PF05837.12 EKX32182.1 - 0.22 11.9 13.1 0.29 11.5 13.1 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) 5_nucleotid PF05761.14 EKX32182.1 - 0.24 10.3 6.7 0.26 10.1 6.7 1.2 1 0 0 1 1 1 0 5' nucleotidase family FUSC PF04632.12 EKX32182.1 - 0.24 9.9 4.4 0.25 9.8 4.4 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family UPF0242 PF06785.11 EKX32182.1 - 0.25 11.4 14.1 0.29 11.2 14.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HAUS6_N PF14661.6 EKX32182.1 - 0.29 10.7 8.6 0.33 10.5 8.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus YabA PF06156.13 EKX32182.1 - 0.32 11.6 11.8 0.41 11.3 11.5 1.4 1 1 0 1 1 1 0 Initiation control protein YabA DUF4446 PF14584.6 EKX32182.1 - 0.35 10.8 5.5 0.49 10.4 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) TMPIT PF07851.13 EKX32182.1 - 0.6 9.3 7.0 0.7 9.1 7.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein Prefoldin PF02996.17 EKX32182.1 - 0.68 9.9 12.6 1.5 8.8 3.6 2.6 1 1 1 2 2 2 0 Prefoldin subunit TSC22 PF01166.18 EKX32182.1 - 0.89 9.9 15.9 1.8 8.9 2.0 3.2 1 1 2 3 3 3 0 TSC-22/dip/bun family Tup_N PF08581.10 EKX32182.1 - 0.95 9.8 14.6 2.2 8.6 3.6 2.9 1 1 0 2 2 2 0 Tup N-terminal LsmAD PF06741.13 EKX32182.1 - 1.1 9.8 4.8 1.9 9.1 4.8 1.5 1 0 0 1 1 1 0 LsmAD domain DUF2570 PF10828.8 EKX32182.1 - 1.5 8.7 13.7 3 7.7 13.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) Syntaxin-6_N PF09177.11 EKX32182.1 - 1.5 9.4 10.0 4.1 8.0 9.9 1.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 EKX32182.1 - 1.6 8.8 9.8 0.61 10.1 4.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) KfrA_N PF11740.8 EKX32182.1 - 2.3 8.9 16.0 54 4.5 16.0 2.1 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term Atg14 PF10186.9 EKX32182.1 - 2.4 7.1 13.1 3.1 6.8 13.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2388 PF09498.10 EKX32182.1 - 2.5 8.2 8.6 14 5.7 0.7 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2388) OmpH PF03938.14 EKX32182.1 - 3.1 8.1 17.6 5.8 7.3 17.4 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) YqjK PF13997.6 EKX32182.1 - 4.1 7.7 6.8 9.5 6.6 1.1 2.2 1 1 1 2 2 2 0 YqjK-like protein DUF4140 PF13600.6 EKX32182.1 - 4.4 7.8 12.9 25 5.4 7.2 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF2203 PF09969.9 EKX32182.1 - 7.7 7.3 9.1 9 7.1 8.6 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) LMBR1 PF04791.16 EKX32182.1 - 9 5.1 5.8 13 4.6 5.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein UPF0449 PF15136.6 EKX32182.1 - 9.8 6.7 15.1 4.6 7.8 4.2 2.2 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Glyco_transf_49 PF13896.6 EKX32183.1 - 1.5e-25 90.2 3.7 3.1e-10 39.9 0.2 3.4 2 1 0 3 3 3 3 Glycosyl-transferase for dystroglycan Beta_helix PF13229.6 EKX32183.1 - 5.6e-06 26.3 0.1 1.1e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 EKX32183.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) TCR PF03638.15 EKX32185.1 - 4.3e-20 71.7 51.3 4e-11 43.0 23.6 2.3 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain SOG2 PF10428.9 EKX32185.1 - 0.06 12.6 11.5 0.087 12.0 11.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein MSL2-CXC PF16682.5 EKX32185.1 - 2.6 8.2 39.8 0.99 9.6 16.1 2.6 2 0 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 SRP-alpha_N PF04086.13 EKX32185.1 - 3.2 7.6 8.6 5.2 6.9 8.6 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Med3 PF11593.8 EKX32185.1 - 6 6.0 16.0 9.1 5.3 16.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PAPA-1 PF04795.12 EKX32186.1 - 1.4e-06 29.0 3.5 1.4e-06 29.0 3.5 2.3 2 1 0 2 2 2 1 PAPA-1-like conserved region DUF2955 PF11168.8 EKX32187.1 - 0.76 9.6 18.2 9.6 6.1 1.2 3.6 1 1 5 6 6 6 0 Protein of unknown function (DUF2955) Rnf-Nqr PF02508.14 EKX32187.1 - 1.7 8.6 26.7 6.9 6.6 9.1 3.3 1 1 2 3 3 3 0 Rnf-Nqr subunit, membrane protein APOBEC1 PF18769.1 EKX32187.1 - 2.6 8.3 25.5 24 5.3 0.7 4.9 1 1 6 7 7 7 0 APOBEC1 WD40 PF00400.32 EKX32188.1 - 3.6e-12 46.6 7.6 0.027 15.3 0.0 7.3 7 1 0 7 7 7 4 WD domain, G-beta repeat Nucleoporin_N PF08801.11 EKX32188.1 - 0.012 14.4 0.0 2.1 7.0 0.0 3.1 3 1 1 4 4 4 0 Nup133 N terminal like Ank_2 PF12796.7 EKX32189.1 - 4.8e-12 46.3 0.1 8.8e-05 23.0 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX32189.1 - 1.1e-10 41.8 0.0 9.2e-06 26.1 0.0 2.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX32189.1 - 4.3e-09 35.9 0.1 0.02 15.4 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 EKX32189.1 - 3e-07 30.6 0.1 0.1 13.1 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EKX32189.1 - 3e-06 27.4 0.0 0.012 15.9 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Leu_zip PF15294.6 EKX32190.1 - 5.7e-07 29.3 5.1 4.1e-06 26.5 1.5 2.0 2 0 0 2 2 2 2 Leucine zipper Drf_FH3 PF06367.16 EKX32190.1 - 0.0055 16.4 2.7 0.006 16.2 2.7 1.1 1 0 0 1 1 1 1 Diaphanous FH3 Domain AAA_lid_7 PF17867.1 EKX32190.1 - 0.028 14.6 0.6 0.083 13.1 0.6 1.9 1 1 0 1 1 1 0 Midasin AAA lid domain Rop-like PF05082.13 EKX32190.1 - 0.065 13.1 1.3 1.3 8.9 0.1 2.2 2 0 0 2 2 2 0 Rop-like Leu_zip PF15294.6 EKX32191.1 - 1.5e-06 28.0 9.3 3.5e-06 26.7 9.3 1.5 1 1 0 1 1 1 1 Leucine zipper PKcGMP_CC PF16808.5 EKX32191.1 - 0.00048 19.9 5.5 0.047 13.5 0.3 2.9 3 0 0 3 3 3 2 Coiled-coil N-terminus of cGMP-dependent protein kinase Csm1_N PF18504.1 EKX32191.1 - 0.00057 20.2 13.0 0.058 13.7 1.8 3.2 1 1 2 3 3 3 2 Csm1 N-terminal domain HMMR_N PF15905.5 EKX32191.1 - 0.002 17.6 6.2 0.0024 17.4 6.2 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal DUF2353 PF09789.9 EKX32191.1 - 0.0024 17.3 5.5 0.0026 17.2 5.5 1.0 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) Fib_alpha PF08702.10 EKX32191.1 - 0.0028 17.8 5.2 0.0037 17.4 5.2 1.1 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Tup_N PF08581.10 EKX32191.1 - 0.003 17.8 7.1 0.23 11.8 3.2 3.1 2 1 0 2 2 2 1 Tup N-terminal Phage_GP20 PF06810.11 EKX32191.1 - 0.0061 16.4 5.8 0.01 15.7 5.8 1.3 1 0 0 1 1 1 1 Phage minor structural protein GP20 DUF484 PF04340.12 EKX32191.1 - 0.0063 16.2 2.8 0.0076 16.0 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF484 Shugoshin_N PF07558.11 EKX32191.1 - 0.015 15.1 0.8 0.015 15.1 0.8 2.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Ax_dynein_light PF10211.9 EKX32191.1 - 0.018 15.0 5.9 0.033 14.1 5.9 1.5 1 1 0 1 1 1 0 Axonemal dynein light chain Phage_GPO PF05929.11 EKX32191.1 - 0.021 14.5 2.3 0.028 14.1 2.3 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Jnk-SapK_ap_N PF09744.9 EKX32191.1 - 0.026 14.8 4.8 0.038 14.2 4.8 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 GAS PF13851.6 EKX32191.1 - 0.043 13.1 10.5 0.24 10.7 10.5 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4201 PF13870.6 EKX32191.1 - 0.058 13.1 7.9 1.2 8.8 8.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Prominin PF05478.11 EKX32191.1 - 0.058 11.4 2.3 0.064 11.2 2.3 1.0 1 0 0 1 1 1 0 Prominin CENP-F_leu_zip PF10473.9 EKX32191.1 - 0.07 13.2 11.7 0.34 10.9 11.7 1.9 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KASH_CCD PF14662.6 EKX32191.1 - 0.074 12.9 8.9 0.12 12.2 8.9 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH PCRF PF03462.18 EKX32191.1 - 0.089 12.7 3.6 0.11 12.4 3.6 1.2 1 0 0 1 1 1 0 PCRF domain bZIP_1 PF00170.21 EKX32191.1 - 0.12 12.5 1.1 0.12 12.5 1.1 2.5 2 1 0 2 2 2 0 bZIP transcription factor Atg14 PF10186.9 EKX32191.1 - 0.14 11.2 7.4 0.18 10.9 7.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DHHA1 PF02272.19 EKX32191.1 - 0.14 12.6 1.5 0.2 12.1 1.5 1.1 1 0 0 1 1 1 0 DHHA1 domain TolA_bind_tri PF16331.5 EKX32191.1 - 0.16 12.0 9.7 0.14 12.3 0.7 2.2 1 1 1 2 2 2 0 TolA binding protein trimerisation KI67R PF08065.12 EKX32191.1 - 0.17 12.4 4.3 0.25 11.9 4.3 1.2 1 0 0 1 1 1 0 KI67R (NUC007) repeat Fungal_TACC PF12709.7 EKX32191.1 - 0.18 12.3 6.9 0.44 11.0 0.9 2.3 1 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins THOC7 PF05615.13 EKX32191.1 - 0.19 12.0 9.4 0.47 10.7 9.4 1.6 1 1 0 1 1 1 0 Tho complex subunit 7 CCDC-167 PF15188.6 EKX32191.1 - 0.19 12.1 9.4 0.32 11.3 0.7 2.3 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Cnn_1N PF07989.11 EKX32191.1 - 0.23 11.7 7.8 2.5 8.3 7.8 2.2 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 TMF_TATA_bd PF12325.8 EKX32191.1 - 0.23 11.7 9.9 0.58 10.4 9.9 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Exonuc_VII_L PF02601.15 EKX32191.1 - 0.27 10.8 4.3 0.31 10.6 4.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit MerR-DNA-bind PF09278.11 EKX32191.1 - 0.31 11.6 8.2 12 6.5 0.2 3.0 1 1 2 3 3 3 0 MerR, DNA binding UPF0449 PF15136.6 EKX32191.1 - 0.36 11.3 6.3 2.7 8.5 1.1 2.2 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 bZIP_2 PF07716.15 EKX32191.1 - 0.39 10.9 0.2 0.39 10.9 0.2 2.8 2 1 0 2 2 2 0 Basic region leucine zipper FlaC_arch PF05377.11 EKX32191.1 - 0.39 11.1 5.4 0.37 11.2 0.8 2.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) TMPIT PF07851.13 EKX32191.1 - 0.41 9.9 4.7 0.52 9.5 4.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein HIP1_clath_bdg PF16515.5 EKX32191.1 - 0.41 11.3 11.7 0.43 11.2 9.1 2.1 1 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Uso1_p115_C PF04871.13 EKX32191.1 - 0.52 10.7 12.3 0.2 12.1 5.6 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region End3 PF12761.7 EKX32191.1 - 0.57 10.3 10.7 5.7 7.1 10.7 1.9 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Pox_A_type_inc PF04508.12 EKX32191.1 - 0.64 10.0 0.1 0.64 10.0 0.1 2.9 4 0 0 4 4 3 0 Viral A-type inclusion protein repeat NPV_P10 PF05531.12 EKX32191.1 - 0.66 10.5 4.2 29 5.2 3.7 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein FAM76 PF16046.5 EKX32191.1 - 0.67 9.3 5.7 0.79 9.0 5.7 1.1 1 0 0 1 1 1 0 FAM76 protein HR1 PF02185.16 EKX32191.1 - 0.69 10.1 10.2 0.72 10.0 1.8 2.4 2 0 0 2 2 2 0 Hr1 repeat AAA_23 PF13476.6 EKX32191.1 - 0.94 9.9 6.7 1.3 9.5 6.7 1.2 1 0 0 1 1 1 0 AAA domain DivIC PF04977.15 EKX32191.1 - 1.1 9.1 12.1 0.67 9.8 2.8 2.6 1 1 1 2 2 2 0 Septum formation initiator Cep57_CLD_2 PF14197.6 EKX32191.1 - 1.1 9.4 8.8 0.71 10.0 1.6 2.9 1 1 0 2 2 2 0 Centrosome localisation domain of PPC89 UPF0242 PF06785.11 EKX32191.1 - 1.2 9.2 10.9 5.5 7.0 10.9 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMF_DNA_bd PF12329.8 EKX32191.1 - 1.3 9.0 16.3 84 3.3 9.1 3.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding ABC_tran_CTD PF16326.5 EKX32191.1 - 1.6 9.0 9.0 1.1 9.6 4.1 2.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain Rho_Binding PF08912.11 EKX32191.1 - 2.1 9.2 10.1 3.1 8.7 5.8 2.6 1 1 1 2 2 2 0 Rho Binding DUF5339 PF17274.2 EKX32191.1 - 3.1 8.7 8.3 12 6.9 1.8 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5339) Evr1_Alr PF04777.13 EKX32192.1 - 2.7e-20 72.7 1.7 2.6e-13 50.3 0.8 2.9 3 0 0 3 3 3 2 Erv1 / Alr family GILT PF03227.16 EKX32192.1 - 9.5e-08 32.3 0.5 1.8e-07 31.3 0.5 1.5 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) DNA_ligase_ZBD PF03119.16 EKX32192.1 - 8.3 6.5 6.5 37 4.5 0.8 2.6 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain DUF1157 PF06636.11 EKX32194.1 - 0.021 13.7 0.5 0.034 13.0 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1157) Colicin-DNase PF12639.7 EKX32198.1 - 0.07 13.9 0.0 0.16 12.8 0.0 1.6 1 0 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin Pkinase PF00069.25 EKX32200.1 - 1e-06 28.3 0.0 2.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EKX32200.1 - 0.0022 17.9 0.0 0.005 16.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EKX32200.1 - 0.0036 17.0 0.1 0.68 9.5 0.0 2.4 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EKX32200.1 - 0.0054 16.1 1.4 0.0072 15.7 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EKX32200.1 - 0.041 13.2 0.0 0.085 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase SAYSvFN PF10260.9 EKX32201.1 - 0.1 12.5 0.1 0.63 10.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) EutC PF05985.11 EKX32203.1 - 0.068 12.5 0.0 0.25 10.6 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine ammonia-lyase light chain (EutC) BMFP PF04380.13 EKX32204.1 - 0.0057 17.1 0.1 1.8 9.1 0.0 2.4 2 1 1 3 3 3 2 Membrane fusogenic activity GAT PF03127.14 EKX32204.1 - 0.081 13.2 0.8 0.26 11.6 0.2 2.1 2 1 1 3 3 3 0 GAT domain PARP_regulatory PF01358.18 EKX32206.1 - 8.6e-23 80.7 0.1 1.1e-22 80.4 0.1 1.1 1 0 0 1 1 1 1 Poly A polymerase regulatory subunit Band_7 PF01145.25 EKX32206.1 - 0.029 14.4 0.5 4.2 7.3 0.0 2.1 2 0 0 2 2 2 0 SPFH domain / Band 7 family Destabilase PF05497.12 EKX32208.1 - 0.061 13.7 1.1 0.52 10.7 0.1 2.6 3 0 0 3 3 3 0 Destabilase Yip1 PF04893.17 EKX32209.1 - 9.1e-18 64.6 9.7 1.1e-17 64.2 9.7 1.1 1 0 0 1 1 1 1 Yip1 domain Ifi-6-16 PF06140.13 EKX32209.1 - 0.097 12.6 2.5 0.13 12.2 0.9 1.9 1 1 1 2 2 2 0 Interferon-induced 6-16 family DNA_pol_phi PF04931.13 EKX32212.1 - 0.0003 19.0 15.6 0.00032 18.9 15.6 1.1 1 0 0 1 1 1 1 DNA polymerase phi Otopetrin PF03189.13 EKX32212.1 - 0.0038 16.1 0.0 0.0046 15.8 0.0 1.0 1 0 0 1 1 1 1 Otopetrin DUF4611 PF15387.6 EKX32212.1 - 0.02 15.1 13.8 0.033 14.4 13.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) eIF-3c_N PF05470.12 EKX32212.1 - 0.029 12.7 0.1 0.029 12.7 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2207 PF09972.9 EKX32212.1 - 0.11 11.3 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RRN3 PF05327.11 EKX32212.1 - 0.26 9.8 12.9 0.3 9.6 12.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2457 PF10446.9 EKX32212.1 - 0.97 8.5 33.1 1.2 8.2 33.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 EKX32212.1 - 1.6 6.9 15.0 2.3 6.4 15.0 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 EKX32212.1 - 2.7 7.2 29.0 3.6 6.8 29.0 1.1 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.11 EKX32212.1 - 2.8 5.9 10.0 3.7 5.5 10.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CobT PF06213.12 EKX32212.1 - 4 6.7 12.5 5.3 6.4 12.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RXT2_N PF08595.11 EKX32212.1 - 4.4 7.3 14.4 6.6 6.7 14.4 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2796 PF10986.8 EKX32212.1 - 4.6 7.2 7.7 6.6 6.7 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) Orf78 PF06024.12 EKX32212.1 - 9.3 6.6 13.9 2.6e+03 -1.2 13.9 2.2 1 1 0 1 1 1 0 Orf78 (ac78) BK_channel_a PF03493.18 EKX32213.1 - 1.9e-17 63.3 0.0 1.1e-16 60.8 0.0 2.2 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 EKX32213.1 - 6.7e-12 45.2 12.2 6.7e-12 45.2 12.2 2.6 2 1 0 2 2 2 1 Ion channel Ion_trans PF00520.31 EKX32213.1 - 1.8e-09 37.2 16.5 2.9e-09 36.5 16.5 1.2 1 0 0 1 1 1 1 Ion transport protein PEN-2 PF10251.9 EKX32213.1 - 0.77 10.2 10.2 0.052 14.0 1.3 2.7 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase XG_FTase PF03254.13 EKX32214.1 - 3.5e-09 35.8 0.0 1.3e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 Xyloglucan fucosyltransferase TPR_2 PF07719.17 EKX32214.1 - 0.015 15.4 1.0 5.9 7.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX32214.1 - 0.02 15.2 0.2 0.083 13.2 0.2 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_21 PF09976.9 EKX32214.1 - 0.079 12.7 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain HAS-barrel PF09378.10 EKX32215.1 - 0.0017 18.4 0.0 0.19 11.9 0.0 2.6 2 1 0 2 2 2 1 HAS barrel domain DivIC PF04977.15 EKX32215.1 - 0.0018 18.0 0.1 0.0036 17.0 0.1 1.5 1 0 0 1 1 1 1 Septum formation initiator Rx_N PF18052.1 EKX32215.1 - 0.004 17.4 3.7 0.0083 16.4 3.7 1.5 1 0 0 1 1 1 1 Rx N-terminal domain ZapB PF06005.12 EKX32215.1 - 0.0066 16.9 3.3 0.014 15.8 3.3 1.5 1 0 0 1 1 1 1 Cell division protein ZapB DUF148 PF02520.17 EKX32215.1 - 0.012 15.7 0.9 0.024 14.8 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF148 TPR_MLP1_2 PF07926.12 EKX32215.1 - 0.014 15.4 3.8 0.023 14.7 3.8 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4446 PF14584.6 EKX32215.1 - 0.023 14.7 1.3 0.039 13.9 0.4 1.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) DUF1664 PF07889.12 EKX32215.1 - 0.034 14.2 1.7 0.034 14.2 1.7 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF1664) Cnn_1N PF07989.11 EKX32215.1 - 0.04 14.1 5.2 0.081 13.1 5.2 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Cortex-I_coil PF09304.10 EKX32215.1 - 0.041 14.1 4.9 0.066 13.4 4.9 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil BST2 PF16716.5 EKX32215.1 - 0.043 14.4 2.8 0.083 13.5 2.8 1.5 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 COG5 PF10392.9 EKX32215.1 - 0.064 13.4 1.1 0.25 11.5 0.6 2.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Prominin PF05478.11 EKX32215.1 - 0.064 11.2 0.9 0.088 10.7 0.9 1.2 1 0 0 1 1 1 0 Prominin DASH_Dam1 PF08653.10 EKX32215.1 - 0.083 12.7 2.6 3.6 7.5 0.7 3.3 2 1 1 3 3 3 0 DASH complex subunit Dam1 CLZ PF16526.5 EKX32215.1 - 0.097 13.0 4.1 0.46 10.9 3.6 2.2 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels YtxH PF12732.7 EKX32215.1 - 0.1 13.1 2.1 0.39 11.3 1.6 2.2 3 0 0 3 3 2 0 YtxH-like protein Fib_alpha PF08702.10 EKX32215.1 - 0.24 11.6 2.8 0.22 11.7 1.3 1.7 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 EKX32215.1 - 0.94 8.7 4.6 0.73 9.0 2.6 1.7 2 0 0 2 2 2 0 TMPIT-like protein YabA PF06156.13 EKX32215.1 - 1 10.0 6.0 2.4 8.8 4.9 2.2 2 1 0 2 2 2 0 Initiation control protein YabA Ovate PF04844.13 EKX32215.1 - 1.2 9.2 6.8 4.2 7.4 3.1 2.5 1 1 1 2 2 2 0 Transcriptional repressor, ovate FlaC_arch PF05377.11 EKX32215.1 - 9.4 6.7 7.5 25 5.4 4.4 3.2 3 1 0 3 3 2 0 Flagella accessory protein C (FlaC) HAS-barrel PF09378.10 EKX32216.1 - 0.0016 18.5 0.0 0.2 11.8 0.0 2.7 2 1 0 2 2 2 1 HAS barrel domain DivIC PF04977.15 EKX32216.1 - 0.0018 18.0 0.1 0.0036 17.0 0.1 1.5 1 0 0 1 1 1 1 Septum formation initiator Rx_N PF18052.1 EKX32216.1 - 0.0041 17.4 3.7 0.0083 16.4 3.7 1.5 1 0 0 1 1 1 1 Rx N-terminal domain ZapB PF06005.12 EKX32216.1 - 0.0067 16.8 3.3 0.014 15.8 3.3 1.5 1 0 0 1 1 1 1 Cell division protein ZapB DUF148 PF02520.17 EKX32216.1 - 0.01 15.9 0.8 0.021 14.9 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF148 TPR_MLP1_2 PF07926.12 EKX32216.1 - 0.014 15.4 3.8 0.023 14.7 3.8 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 EKX32216.1 - 0.024 14.6 1.3 0.024 14.6 1.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4446 PF14584.6 EKX32216.1 - 0.028 14.4 1.6 0.042 13.8 0.4 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) Cortex-I_coil PF09304.10 EKX32216.1 - 0.039 14.2 4.9 0.066 13.4 4.9 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil Cnn_1N PF07989.11 EKX32216.1 - 0.041 14.0 5.2 0.081 13.1 5.2 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 BST2 PF16716.5 EKX32216.1 - 0.045 14.3 2.8 0.083 13.5 2.8 1.4 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 Prominin PF05478.11 EKX32216.1 - 0.059 11.3 0.8 0.081 10.9 0.8 1.2 1 0 0 1 1 1 0 Prominin COG5 PF10392.9 EKX32216.1 - 0.067 13.4 1.3 0.32 11.2 1.2 2.1 1 1 1 2 2 2 0 Golgi transport complex subunit 5 CLZ PF16526.5 EKX32216.1 - 0.11 12.8 4.3 0.5 10.8 3.5 2.2 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels YtxH PF12732.7 EKX32216.1 - 0.15 12.6 2.5 0.39 11.3 1.6 2.2 2 1 0 2 2 2 0 YtxH-like protein Fib_alpha PF08702.10 EKX32216.1 - 0.29 11.3 3.0 0.25 11.5 1.4 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DASH_Dam1 PF08653.10 EKX32216.1 - 0.35 10.7 2.2 3.6 7.5 0.7 2.8 1 1 1 2 2 2 0 DASH complex subunit Dam1 YabA PF06156.13 EKX32216.1 - 0.86 10.3 5.6 2.2 8.9 4.7 2.2 2 1 0 2 2 2 0 Initiation control protein YabA TMPIT PF07851.13 EKX32216.1 - 0.96 8.6 4.6 0.73 9.0 2.6 1.7 2 0 0 2 2 2 0 TMPIT-like protein Ovate PF04844.13 EKX32216.1 - 1.2 9.2 6.8 4.2 7.4 3.1 2.5 1 1 1 2 2 2 0 Transcriptional repressor, ovate LSDAT_euk PF18139.1 EKX32217.1 - 0.42 9.9 14.1 0.88 8.9 1.5 3.0 3 0 0 3 3 3 0 SLOG in TRPM Pilin_PilA PF14245.6 EKX32217.1 - 5.9 6.9 11.0 39 4.2 0.5 3.7 3 0 0 3 3 3 0 Type IV pilin PilA HSP70 PF00012.20 EKX32218.1 - 4.3e-21 74.7 12.0 2.4e-20 72.3 0.3 3.0 3 0 0 3 3 3 2 Hsp70 protein FtsA PF14450.6 EKX32218.1 - 0.018 15.4 0.2 0.73 10.3 0.0 3.0 3 1 0 3 3 3 0 Cell division protein FtsA DUF812 PF05667.11 EKX32218.1 - 0.042 12.7 9.4 0.069 12.0 9.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CENP-F_leu_zip PF10473.9 EKX32218.1 - 0.17 11.9 12.9 0.52 10.3 12.9 1.8 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BcrAD_BadFG PF01869.20 EKX32218.1 - 0.22 11.0 5.2 2.9 7.3 0.0 2.9 4 0 0 4 4 4 0 BadF/BadG/BcrA/BcrD ATPase family Pox_A11 PF05061.13 EKX32218.1 - 0.25 10.6 0.9 0.39 10.0 0.3 1.6 2 0 0 2 2 2 0 Poxvirus A11 Protein Spectrin PF00435.21 EKX32218.1 - 0.33 11.5 7.6 7.5 7.1 3.0 2.8 1 1 1 2 2 2 0 Spectrin repeat Tropomyosin PF00261.20 EKX32218.1 - 0.86 8.9 24.0 0.7 9.2 21.2 2.2 2 1 0 2 2 2 0 Tropomyosin Golgin_A5 PF09787.9 EKX32218.1 - 1.1 8.7 9.0 2.2 7.7 9.0 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4200 PF13863.6 EKX32218.1 - 2.5 8.5 17.5 9.4 6.7 5.3 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) PI3K_P85_iSH2 PF16454.5 EKX32218.1 - 4.4 6.9 7.2 14 5.2 7.2 1.8 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Cystatin PF00031.21 EKX32219.1 - 1.9e-05 24.9 0.1 2.1e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Cystatin domain Cpn60_TCP1 PF00118.24 EKX32220.1 - 4.2e-161 536.9 0.1 4.8e-161 536.7 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF5614 PF18474.1 EKX32220.1 - 0.0014 18.0 0.1 0.0024 17.2 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5614) DUF2121 PF09894.9 EKX32220.1 - 0.0018 17.9 0.1 0.0036 16.9 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2121) Beta_helix_2 PF18835.1 EKX32220.1 - 0.067 13.0 0.1 20 5.0 0.1 2.8 2 0 0 2 2 2 0 Beta helix repeat of Inulin fructotransferase Pkinase PF00069.25 EKX32221.1 - 1.6e-05 24.4 0.0 2.1e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SAM_1 PF00536.30 EKX32221.1 - 0.16 12.5 0.0 0.31 11.5 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Hormone_5 PF00184.17 EKX32222.1 - 0.062 14.1 10.9 53 4.7 10.9 2.5 1 1 0 1 1 1 0 Neurohypophysial hormones, C-terminal Domain Keratin_B2_2 PF13885.6 EKX32222.1 - 1.9 8.5 17.2 20 5.2 7.8 2.3 1 1 1 2 2 2 0 Keratin, high sulfur B2 protein Defensin_1 PF00323.19 EKX32222.1 - 6.6 7.4 9.1 83 3.9 0.6 3.5 1 1 6 7 7 7 0 Mammalian defensin Reo_P9 PF06043.11 EKX32223.1 - 2.4e-05 23.9 18.4 0.46 9.9 1.5 4.5 1 1 5 6 6 6 6 Reovirus P9-like family PMG PF05287.12 EKX32223.1 - 0.15 12.1 23.3 1.8e+04 -4.8 23.3 3.0 1 1 0 1 1 1 0 PMG protein DUF1652 PF07865.11 EKX32223.1 - 0.16 11.8 13.7 73 3.3 0.1 6.1 1 1 10 11 11 11 0 Protein of unknown function (DUF1652) pPIWI_RE_Z PF18155.1 EKX32223.1 - 9.4 6.1 21.7 20 5.0 3.3 4.2 1 1 2 3 3 3 0 pPIWI RE three-gene island domain Z SET PF00856.28 EKX32226.1 - 8.7e-10 39.2 0.0 1.6e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 SET domain Baculo_gp64 PF03273.13 EKX32226.1 - 0.057 12.2 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family Ras PF00071.22 EKX32227.1 - 2.9e-17 62.7 0.0 5.8e-15 55.3 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EKX32227.1 - 7.9e-17 61.6 0.0 1.9e-16 60.3 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EKX32227.1 - 3.2e-07 30.0 0.0 9.9e-06 25.1 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EKX32227.1 - 4.8e-06 26.6 0.0 8.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EKX32227.1 - 5e-06 26.1 0.0 8.4e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EKX32227.1 - 0.003 17.5 0.0 0.056 13.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EKX32227.1 - 0.0083 16.5 0.1 0.013 15.8 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain IIGP PF05049.13 EKX32227.1 - 0.059 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 EKX32227.1 - 0.077 13.3 0.0 0.27 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EKX32227.1 - 0.089 13.3 0.1 0.14 12.6 0.1 1.5 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 EKX32227.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Arm PF00514.23 EKX32228.1 - 5.9e-05 23.0 0.0 0.17 12.0 0.0 4.7 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EKX32228.1 - 0.0001 22.6 7.5 0.0092 16.4 0.1 3.7 1 1 3 4 4 4 1 HEAT repeats Atx10homo_assoc PF09759.9 EKX32228.1 - 0.0085 16.1 0.0 1.1 9.4 0.0 2.8 1 1 1 3 3 3 1 Spinocerebellar ataxia type 10 protein domain zf-CW PF07496.15 EKX32228.1 - 0.0093 16.0 0.2 0.11 12.6 0.1 2.3 2 0 0 2 2 2 1 CW-type Zinc Finger Tyr-DNA_phospho PF06087.12 EKX32228.1 - 0.026 13.4 0.4 0.035 13.0 0.4 1.4 1 1 0 1 1 1 0 Tyrosyl-DNA phosphodiesterase ArAE_1_C PF11728.8 EKX32228.1 - 0.12 12.3 0.2 1.7 8.6 0.1 2.1 2 1 0 2 2 2 0 Putative aromatic acid exporter C-terminal domain Pkinase_Tyr PF07714.17 EKX32229.1 - 2.4e-38 131.9 0.0 2.6e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX32229.1 - 4.2e-15 55.8 0.0 4.7e-15 55.7 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain U-box PF04564.15 EKX32230.1 - 2.2e-19 69.4 0.0 2.6e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX32230.1 - 1.8e-05 24.5 0.0 2.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EKX32230.1 - 0.00018 21.5 0.1 0.00028 20.9 0.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-NOSIP PF15906.5 EKX32230.1 - 0.011 15.9 0.0 0.014 15.5 0.0 1.1 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein DUF1090 PF06476.12 EKX32231.1 - 1.3e-07 31.7 61.6 0.3 11.2 2.1 11.4 3 3 9 13 13 13 11 Protein of unknown function (DUF1090) Glyco_hydro_46 PF01374.18 EKX32231.1 - 8.1e-06 25.6 12.5 1.5 8.4 0.3 5.7 2 2 6 8 8 8 5 Glycosyl hydrolase family 46 DUF3769 PF12600.8 EKX32231.1 - 0.033 13.1 5.7 2.3 7.0 0.2 3.8 2 2 2 4 4 4 0 Protein of unknown function (DUF3769) PSII_Pbs31 PF18240.1 EKX32231.1 - 0.49 10.9 9.5 8.9 6.8 0.1 5.7 3 2 4 7 7 7 0 Photosystem II Psb31 protein UPF0556 PF10572.9 EKX32231.1 - 5.1 6.6 10.7 17 4.9 0.1 5.5 3 3 4 8 8 8 0 Uncharacterised protein family UPF0556 PARP PF00644.20 EKX32232.1 - 1.1e-24 87.2 0.0 5.2e-24 84.9 0.0 2.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain ERM PF00769.19 EKX32232.1 - 0.0035 17.2 7.1 0.0049 16.7 7.1 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Exotox-A_cataly PF09009.10 EKX32232.1 - 0.046 13.5 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 Exotoxin A catalytic Phage_integrase PF00589.22 EKX32232.1 - 0.12 12.1 1.1 0.24 11.1 1.1 1.7 1 1 0 1 1 1 0 Phage integrase family Spc7 PF08317.11 EKX32232.1 - 0.13 11.1 7.7 0.2 10.5 7.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Spc24 PF08286.11 EKX32232.1 - 0.15 12.3 4.5 0.28 11.4 4.5 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF3338 PF11819.8 EKX32232.1 - 0.3 11.1 8.0 0.6 10.1 8.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3338) OmpH PF03938.14 EKX32232.1 - 0.33 11.3 13.8 0.53 10.6 13.3 1.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Pkinase PF00069.25 EKX32233.1 - 2.2e-27 96.1 0.0 2.4e-27 96.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX32233.1 - 1e-15 57.8 0.0 1.1e-15 57.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX32233.1 - 9.1e-09 34.6 0.0 1.1e-08 34.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EKX32233.1 - 9.9e-06 25.1 0.4 1.3e-05 24.7 0.4 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX32233.1 - 0.0059 16.5 0.7 0.011 15.7 0.7 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EKX32233.1 - 0.037 13.6 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 EKX32233.1 - 0.086 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL WD40 PF00400.32 EKX32234.1 - 1.9e-63 208.8 32.3 3.4e-08 34.0 0.4 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat WD40_like PF17005.5 EKX32234.1 - 1.3e-10 41.1 0.0 0.12 11.7 0.0 5.2 3 1 3 6 6 6 4 WD40-like domain Nup160 PF11715.8 EKX32234.1 - 1.2e-09 37.4 14.2 0.13 10.9 0.0 7.6 1 1 6 8 8 8 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EKX32234.1 - 8.8e-08 31.1 8.8 0.015 13.9 0.1 4.0 1 1 3 4 4 4 4 Cytochrome D1 heme domain Nbas_N PF15492.6 EKX32234.1 - 9.4e-07 28.4 5.8 0.97 8.7 0.0 5.5 1 1 4 5 5 5 2 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 EKX32234.1 - 1.1e-05 24.4 2.3 0.43 9.3 0.1 5.2 1 1 3 4 4 4 2 Nup133 N terminal like PQQ_3 PF13570.6 EKX32234.1 - 0.0037 17.7 19.8 11 6.6 0.2 7.3 8 0 0 8 8 8 1 PQQ-like domain VID27 PF08553.10 EKX32234.1 - 0.0038 16.3 7.3 2.2 7.2 0.1 3.8 1 1 3 4 4 4 2 VID27 C-terminal WD40-like domain Bactofilin PF04519.13 EKX32234.1 - 0.0063 16.8 7.0 0.67 10.3 0.1 4.1 1 1 2 4 4 4 2 Polymer-forming cytoskeletal GHD PF17834.1 EKX32234.1 - 0.01 15.8 0.8 69 3.6 0.0 5.0 5 0 0 5 5 5 0 Beta-sandwich domain in beta galactosidase PALB2_WD40 PF16756.5 EKX32234.1 - 0.022 13.7 21.4 1.4 7.8 1.0 5.0 1 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Alfin PF12165.8 EKX32234.1 - 0.061 13.0 0.1 22 4.7 0.0 4.0 3 2 1 4 4 4 0 Alfin RE_Eco29kI PF09517.10 EKX32234.1 - 0.19 11.4 0.5 6.8 6.3 0.0 3.1 3 2 0 3 3 3 0 Eco29kI restriction endonuclease FG-GAP_2 PF14312.6 EKX32234.1 - 0.28 11.4 29.1 10 6.5 0.3 7.3 8 0 0 8 8 8 0 FG-GAP repeat CagY_M PF07337.11 EKX32234.1 - 1.4 8.6 7.3 18 5.0 0.0 4.9 6 0 0 6 6 6 0 DC-EC Repeat WD40 PF00400.32 EKX32235.1 - 2.6e-13 50.2 4.5 7.8e-09 36.0 1.5 2.0 2 0 0 2 2 2 2 WD domain, G-beta repeat FG-GAP_2 PF14312.6 EKX32235.1 - 0.021 15.1 1.3 5.5 7.3 0.1 2.1 2 0 0 2 2 2 0 FG-GAP repeat VID27 PF08553.10 EKX32235.1 - 0.038 13.1 0.1 0.04 13.0 0.1 1.0 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain Glucodextran_B PF09136.10 EKX32235.1 - 0.14 12.5 1.8 7.5 7.0 0.2 2.1 1 1 1 2 2 2 0 Glucodextranase, domain B Ank_2 PF12796.7 EKX32236.1 - 7.1e-71 234.8 17.2 4.7e-10 39.9 0.0 8.5 1 1 8 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX32236.1 - 6.5e-55 182.8 1.7 1.3e-06 28.9 0.0 10.8 5 3 8 13 13 13 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX32236.1 - 1.3e-43 146.5 18.2 0.0035 17.6 0.0 15.5 5 3 11 16 16 16 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX32236.1 - 3.4e-31 103.8 0.8 0.72 10.6 0.0 15.0 17 0 0 17 17 16 5 Ankyrin repeat Ank PF00023.30 EKX32236.1 - 1e-19 70.0 6.1 6.2 7.5 0.0 13.6 15 0 0 15 15 14 1 Ankyrin repeat Ins_beta PF03488.14 EKX32236.1 - 0.00047 20.1 27.1 35 4.5 0.0 13.0 15 0 0 15 15 15 0 Nematode insulin-related peptide beta type Chol_subst-bind PF09129.11 EKX32236.1 - 0.00055 19.0 0.0 69 2.2 0.0 7.0 5 2 6 11 11 11 0 Cholesterol oxidase, substrate-binding DUF4116 PF13475.6 EKX32236.1 - 0.002 17.8 0.0 93 2.9 0.0 6.3 7 1 0 7 7 7 0 Domain of unknown function (DUF4116) zf-NADH-PPase PF09297.11 EKX32236.1 - 0.0053 16.4 11.2 8.9 6.1 0.1 6.1 5 0 0 5 5 5 3 NADH pyrophosphatase zinc ribbon domain AAA_27 PF13514.6 EKX32236.1 - 0.0058 16.2 0.6 38 3.8 0.0 4.5 4 0 0 4 4 4 0 AAA domain MA3 PF02847.17 EKX32236.1 - 0.0062 16.5 1.1 55 3.8 0.0 6.2 5 3 3 8 8 8 0 MA3 domain SPATA24 PF15175.6 EKX32236.1 - 0.22 11.4 0.7 1.4e+02 2.2 0.0 4.4 4 2 1 6 6 6 0 Spermatogenesis-associated protein 24 eRF1_3 PF03465.15 EKX32236.1 - 0.3 11.6 2.8 14 6.2 0.1 4.2 3 2 0 3 3 3 0 eRF1 domain 3 BDHCT PF08072.11 EKX32236.1 - 1.4 9.0 32.4 4.6 7.4 0.1 11.6 14 0 0 14 14 14 0 BDHCT (NUC031) domain Arm PF00514.23 EKX32238.1 - 8.7e-28 95.5 8.4 2.1e-05 24.4 0.1 6.8 8 0 0 8 8 8 5 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EKX32238.1 - 9.4e-14 51.2 0.1 0.00062 19.7 0.0 5.2 1 1 5 7 7 7 4 Spinocerebellar ataxia type 10 protein domain V-ATPase_H_C PF11698.8 EKX32238.1 - 5.8e-06 26.4 2.1 0.28 11.3 0.1 3.7 2 1 2 4 4 4 3 V-ATPase subunit H HEAT_EZ PF13513.6 EKX32238.1 - 0.00013 22.4 25.2 0.015 15.8 1.3 6.0 3 1 4 7 7 7 5 HEAT-like repeat DUF4630 PF15443.6 EKX32238.1 - 0.0013 19.0 34.1 0.14 12.3 1.3 6.6 1 1 6 7 7 7 4 Domain of unknown function (DUF4630) Bromo_TP PF07524.13 EKX32238.1 - 0.054 13.5 7.5 30 4.7 0.0 4.6 4 1 1 5 5 5 0 Bromodomain associated DUF3877 PF12993.7 EKX32238.1 - 0.11 12.3 0.1 13 5.6 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) HEAT PF02985.22 EKX32238.1 - 0.41 11.0 18.5 3.6 8.1 0.1 6.6 8 0 0 8 8 8 0 HEAT repeat Pkinase_Tyr PF07714.17 EKX32239.1 - 1.5e-38 132.6 0.0 1.6e-38 132.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX32239.1 - 2.2e-14 53.5 0.0 2.5e-14 53.3 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain U-box PF04564.15 EKX32240.1 - 5.1e-18 65.0 0.0 5.5e-18 64.9 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-RING_UBOX PF13445.6 EKX32240.1 - 0.0002 21.3 0.2 0.00029 20.8 0.2 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.8 EKX32240.1 - 0.00047 19.9 0.1 0.00067 19.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 EKX32240.1 - 0.053 13.7 0.1 0.073 13.2 0.1 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-NOSIP PF15906.5 EKX32240.1 - 0.076 13.2 0.0 0.093 12.9 0.0 1.2 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein DUF1090 PF06476.12 EKX32241.1 - 1.1e-05 25.4 51.0 1 9.5 2.9 9.3 2 2 6 10 10 10 9 Protein of unknown function (DUF1090) Peptidase_U32_C PF16325.5 EKX32241.1 - 0.062 13.6 11.1 14 6.1 0.1 5.5 4 2 2 6 6 6 0 Peptidase family U32 C-terminal domain DUF3769 PF12600.8 EKX32241.1 - 0.45 9.3 4.1 1.6 7.5 0.2 2.9 2 2 3 5 5 5 0 Protein of unknown function (DUF3769) MoCF_biosynth PF00994.24 EKX32241.1 - 5.3 6.7 9.5 4.2 7.0 0.1 3.9 2 1 1 4 4 4 0 Probable molybdopterin binding domain Pkinase_Tyr PF07714.17 EKX32242.1 - 4.3e-58 196.6 0.0 5.1e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX32242.1 - 1.2e-24 87.2 0.0 1.5e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 EKX32243.1 - 8.7e-21 73.9 17.0 7e-05 23.5 0.3 4.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Nbas_N PF15492.6 EKX32243.1 - 0.00072 19.0 1.0 0.099 12.0 0.1 2.8 1 1 2 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 EKX32243.1 - 0.015 14.1 0.2 0.018 13.8 0.2 1.1 1 0 0 1 1 1 0 Nup133 N terminal like Nup160 PF11715.8 EKX32243.1 - 0.017 13.8 3.7 1.8 7.1 0.2 2.7 1 1 1 3 3 3 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EKX32243.1 - 0.024 13.2 1.0 0.19 10.2 0.3 2.0 1 1 1 2 2 2 0 Cytochrome D1 heme domain VID27 PF08553.10 EKX32243.1 - 0.046 12.8 0.3 0.52 9.3 0.2 2.2 1 1 1 2 2 2 0 VID27 C-terminal WD40-like domain WD40 PF00400.32 EKX32244.1 - 3.7e-16 59.2 5.5 1.3e-08 35.3 0.2 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat FG-GAP_2 PF14312.6 EKX32244.1 - 0.037 14.3 0.3 6.6 7.1 0.0 2.2 2 0 0 2 2 2 0 FG-GAP repeat Ank_2 PF12796.7 EKX32245.1 - 3.7e-43 146.0 3.2 4.2e-10 40.1 0.5 4.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX32245.1 - 5.8e-36 122.4 5.6 3.1e-09 37.2 0.0 6.3 5 2 2 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX32245.1 - 7e-30 102.7 9.7 0.0014 18.9 0.0 8.2 3 1 5 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX32245.1 - 4.1e-25 85.1 5.6 0.12 13.0 0.0 9.1 9 0 0 9 9 9 7 Ankyrin repeat Ank PF00023.30 EKX32245.1 - 3.2e-14 52.6 6.5 0.62 10.6 0.0 8.9 9 0 0 9 9 9 3 Ankyrin repeat BTHB PF18410.1 EKX32245.1 - 0.0013 18.5 0.0 8.1 6.3 0.0 4.7 3 2 3 6 6 6 1 Basic tilted helix bundle domain AvrM_N PF18247.1 EKX32245.1 - 0.057 13.4 0.7 3.7e+02 1.2 0.0 5.1 6 0 0 6 6 6 0 Flax-rust effector AvrM N-terminal domain DUF5049 PF16468.5 EKX32245.1 - 0.15 12.0 0.0 31 4.6 0.0 4.2 6 0 0 6 6 6 0 Domain of unknown function (DUF5049) SSI PF00720.17 EKX32245.1 - 0.81 9.7 5.7 9.2 6.3 0.0 4.2 4 1 1 5 5 5 0 Subtilisin inhibitor-like YhfH PF14149.6 EKX32245.1 - 10 6.2 6.9 0.73 9.9 0.2 2.7 3 0 0 3 3 3 0 YhfH-like protein Filamin PF00630.19 EKX32246.1 - 1e-09 39.1 0.0 0.34 11.8 0.0 4.6 4 0 0 4 4 4 4 Filamin/ABP280 repeat Ephrin_rec_like PF07699.13 EKX32247.1 - 3.1e-15 55.7 117.4 5.1e-08 32.5 6.4 10.8 4 4 8 12 12 12 9 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX32247.1 - 9.8e-09 35.5 99.5 1.2e-07 32.0 10.4 10.3 4 3 7 12 12 12 6 TNFR/NGFR cysteine-rich region NCD3G PF07562.14 EKX32247.1 - 0.00017 21.5 3.4 0.00017 21.5 3.4 9.3 4 3 5 9 9 9 6 Nine Cysteines Domain of family 3 GPCR E3_UbLigase_EDD PF11547.8 EKX32250.1 - 0.17 11.6 0.1 0.27 10.9 0.1 1.2 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD zf-C2H2 PF00096.26 EKX32251.1 - 0.0017 18.7 2.1 0.0017 18.7 2.1 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EKX32251.1 - 0.004 17.9 2.7 0.034 15.0 2.7 2.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-BED PF02892.15 EKX32251.1 - 0.011 15.8 3.1 0.029 14.4 3.1 1.7 1 0 0 1 1 1 0 BED zinc finger zf-C2H2_jaz PF12171.8 EKX32251.1 - 0.021 15.1 2.8 0.021 15.1 2.8 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Polysacc_synt PF01943.17 EKX32251.1 - 0.06 12.7 0.1 0.083 12.3 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TadE PF07811.12 EKX32251.1 - 0.87 9.9 3.6 1.7 9.0 3.6 1.4 1 0 0 1 1 1 0 TadE-like protein DUF3899 PF13038.6 EKX32251.1 - 1 9.9 3.5 19 5.8 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3899) Pribosyltran_N PF13793.6 EKX32253.1 - 1e-45 154.4 0.0 4.1e-45 152.5 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EKX32253.1 - 8.2e-19 68.4 0.0 1.4e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EKX32253.1 - 1.2e-13 50.9 0.0 4.5e-13 49.0 0.0 1.9 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EKX32253.1 - 0.091 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase TPR_1 PF00515.28 EKX32254.1 - 1.4e-26 91.2 0.5 1.2e-07 31.3 0.0 5.4 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX32254.1 - 9.7e-24 81.5 7.6 1.1e-07 31.4 0.0 5.4 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 EKX32254.1 - 6.9e-22 77.5 12.1 4.1e-14 52.6 3.6 4.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX32254.1 - 3.5e-19 67.3 0.2 0.00044 20.2 0.0 5.1 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX32254.1 - 2.1e-17 61.8 9.6 6.6e-06 25.8 0.0 5.6 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX32254.1 - 6.3e-15 54.6 0.2 1.4e-06 27.8 0.0 5.1 5 1 1 6 6 6 3 TPR repeat TPR_14 PF13428.6 EKX32254.1 - 1.5e-14 53.5 8.6 0.00017 22.1 0.0 4.8 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EKX32254.1 - 3.6e-14 53.0 2.8 6.2e-08 33.0 0.1 2.4 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX32254.1 - 3.2e-13 49.1 13.5 1.8e-05 24.5 0.2 4.3 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX32254.1 - 1.1e-11 45.2 10.0 1.1e-05 25.9 2.7 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 EKX32254.1 - 3.2e-09 36.5 1.8 0.066 13.6 0.0 4.9 6 1 0 6 6 5 3 Tetratricopeptide repeat TPR_4 PF07721.14 EKX32254.1 - 2.4e-07 30.7 10.3 0.00013 22.2 1.1 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX32254.1 - 3.4e-07 30.0 5.5 2.1e-06 27.3 4.4 2.4 1 1 0 1 1 1 1 MalT-like TPR region TPR_9 PF13371.6 EKX32254.1 - 2.4e-06 27.6 8.0 0.00069 19.7 1.6 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX32254.1 - 9.1e-05 22.8 3.7 1.9 9.3 0.0 4.5 4 1 2 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX32254.1 - 0.0014 18.8 3.4 0.19 12.0 1.1 2.7 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 EKX32254.1 - 0.0031 17.5 1.6 14 5.8 0.0 3.9 3 1 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 EKX32254.1 - 0.011 15.0 1.1 1.7 7.8 0.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 EKX32254.1 - 0.012 15.5 2.3 0.052 13.5 0.6 2.0 1 1 1 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal TPR_21 PF09976.9 EKX32254.1 - 0.071 12.8 0.6 0.31 10.7 0.3 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain ANAPC5 PF12862.7 EKX32254.1 - 0.073 13.1 0.7 1.8 8.7 0.2 2.6 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 PLA1 PF02253.15 EKX32254.1 - 0.087 12.4 0.5 1.5 8.3 0.1 2.0 1 1 1 2 2 2 0 Phospholipase A1 YqaH PF17448.2 EKX32254.1 - 0.091 13.1 0.2 1.6 9.1 0.0 2.8 3 1 1 4 4 4 0 Uncharacterized YqaH-like MIT PF04212.18 EKX32254.1 - 0.16 12.0 7.0 3.7 7.7 0.6 4.3 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain BTAD PF03704.17 EKX32254.1 - 0.72 10.3 10.2 2.7 8.4 0.1 2.6 3 0 0 3 3 3 0 Bacterial transcriptional activator domain Ephrin_rec_like PF07699.13 EKX32255.1 - 8e-09 35.1 202.2 0.00038 20.1 5.9 17.2 7 7 8 16 16 16 13 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX32255.1 - 6.3e-06 26.5 4.5 6.3e-06 26.5 4.5 17.9 8 7 11 19 19 19 9 TNFR/NGFR cysteine-rich region TauE PF01925.19 EKX32257.1 - 1.6e-09 37.8 19.2 4.8e-08 32.9 15.0 3.3 2 1 0 2 2 2 1 Sulfite exporter TauE/SafE Metal_resist PF13801.6 EKX32257.1 - 0.0089 16.2 1.4 0.013 15.7 0.2 1.8 2 0 0 2 2 2 1 Heavy-metal resistance DNA_pack_N PF02500.15 EKX32257.1 - 0.013 15.4 0.9 0.027 14.3 0.9 1.4 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus Cyclin_N PF00134.23 EKX32258.1 - 1.1e-18 67.1 0.0 1.9e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EKX32258.1 - 7.2e-11 42.2 0.5 1.2e-08 35.0 0.1 2.3 1 1 1 2 2 2 2 Cyclin, C-terminal domain LRR_6 PF13516.6 EKX32259.1 - 1.2e-13 49.9 0.1 0.0061 16.5 0.0 5.5 6 0 0 6 6 6 3 Leucine Rich repeat RIIa PF02197.17 EKX32259.1 - 1.2e-08 34.5 0.0 2.1e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit LRR_8 PF13855.6 EKX32259.1 - 7.2e-05 22.5 1.2 0.022 14.5 0.2 4.2 3 2 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 EKX32259.1 - 0.00049 20.4 0.1 0.13 12.7 0.0 3.6 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX32259.1 - 0.0088 16.4 0.1 8.4 7.4 0.0 3.9 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 EKX32260.1 - 6.7e-17 60.0 0.6 0.0044 17.0 0.0 6.5 7 0 0 7 7 7 5 Leucine Rich repeat LRR_8 PF13855.6 EKX32260.1 - 1.1e-05 25.0 1.4 0.016 14.9 0.3 4.6 3 2 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 EKX32260.1 - 0.00011 22.5 0.1 0.09 13.2 0.0 4.1 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX32260.1 - 0.00022 21.3 0.2 6.2 7.8 0.1 5.0 6 0 0 6 6 6 1 Leucine Rich Repeat Kelch_2 PF07646.15 EKX32261.1 - 0.03 14.3 2.7 2.9 8.0 0.5 2.8 2 1 0 2 2 2 0 Kelch motif EF-hand_6 PF13405.6 EKX32263.1 - 7.3e-23 78.5 2.2 8.3e-06 25.3 0.0 4.2 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 EKX32263.1 - 2.5e-21 74.1 1.0 5.1e-06 25.7 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_1 PF00036.32 EKX32263.1 - 2.5e-17 61.0 18.5 2.4e-05 23.6 0.0 6.0 6 2 2 8 8 8 3 EF hand EF-hand_7 PF13499.6 EKX32263.1 - 1.5e-13 51.0 16.8 0.00061 20.2 1.1 4.1 3 3 0 3 3 3 3 EF-hand domain pair C2 PF00168.30 EKX32263.1 - 3.4e-09 36.9 0.0 6.2e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 C2 domain SPARC_Ca_bdg PF10591.9 EKX32263.1 - 1.9e-07 31.4 0.0 0.59 10.5 0.0 3.3 3 0 0 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 EKX32263.1 - 0.0001 22.1 8.2 1.8 8.4 0.0 5.4 6 0 0 6 6 6 2 EF-hand domain pair RelE PF06296.12 EKX32263.1 - 0.19 11.9 0.3 1.7e+02 2.3 0.0 3.7 5 0 0 5 5 5 0 RelE toxin of RelE / RelB toxin-antitoxin system DUF5109 PF17134.4 EKX32263.1 - 1.8 8.5 5.1 74 3.3 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5109) PATR PF12951.7 EKX32263.1 - 3.9 7.7 7.3 77 3.5 0.2 3.3 3 0 0 3 3 3 0 Passenger-associated-transport-repeat Ish1 PF10281.9 EKX32263.1 - 9.1 6.7 14.9 37 4.8 0.8 3.9 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein EF-hand_10 PF14788.6 EKX32263.1 - 9.5 6.2 15.3 7.2 6.6 0.0 4.7 6 0 0 6 6 6 0 EF hand Pinin_SDK_N PF04697.13 EKX32264.1 - 0.046 14.4 0.3 0.076 13.7 0.3 1.4 1 0 0 1 1 1 0 pinin/SDK conserved region FKBP_C PF00254.28 EKX32265.1 - 1.4e-28 99.1 0.1 6.2e-10 39.3 0.0 3.3 3 0 0 3 3 3 3 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N_2 PF18023.1 EKX32265.1 - 1.3e-06 28.5 0.0 0.0038 17.3 0.0 3.4 2 1 0 2 2 2 2 BDBT FKBP like N-terminal TPR_1 PF00515.28 EKX32265.1 - 9.4e-06 25.2 1.8 0.57 10.1 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX32265.1 - 2.5e-05 24.3 0.0 5.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX32265.1 - 0.00075 19.4 5.6 1.2 9.4 0.1 4.1 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX32265.1 - 0.0022 18.4 0.6 0.0081 16.6 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX32265.1 - 0.0034 17.9 1.0 15 6.5 0.1 4.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX32265.1 - 0.0063 17.1 0.2 0.026 15.2 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX32265.1 - 0.037 14.3 0.7 0.18 12.1 0.2 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EKX32265.1 - 0.048 13.4 0.5 1 9.1 0.0 2.8 3 0 0 3 3 3 0 TPR repeat TPR_12 PF13424.6 EKX32265.1 - 0.058 13.7 0.1 0.42 10.9 0.1 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat Peptidase_C50 PF03568.17 EKX32266.1 - 2.5e-78 263.9 1.3 8.8e-66 222.6 0.0 2.9 1 1 1 2 2 2 2 Peptidase family C50 SAP PF02037.27 EKX32266.1 - 2.5e-12 46.2 0.2 7.8e-12 44.7 0.2 2.0 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 EKX32266.1 - 0.00044 19.9 0.1 0.0012 18.5 0.1 1.7 1 0 0 1 1 1 1 HeH/LEM domain CHAT PF12770.7 EKX32266.1 - 0.12 11.7 6.3 0.21 11.0 0.0 3.3 3 2 0 4 4 4 0 CHAT domain RINGv PF12906.7 EKX32267.1 - 0.0065 16.6 1.6 0.01 16.0 1.6 1.3 1 0 0 1 1 1 1 RING-variant domain NP1-WLL PF11733.8 EKX32267.1 - 0.015 15.1 3.1 0.019 14.8 0.0 2.0 2 0 0 2 2 2 0 Non-capsid protein NP1 HEAT_2 PF13646.6 EKX32268.1 - 0.00029 21.2 6.0 0.058 13.8 2.3 2.6 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 EKX32268.1 - 0.019 15.2 9.1 13 6.3 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat U3snoRNP10 PF12397.8 EKX32268.1 - 0.054 13.8 1.5 2.8 8.3 0.2 3.4 2 2 1 3 3 3 0 U3 small nucleolar RNA-associated protein 10 NEMP PF10225.9 EKX32268.1 - 0.066 12.9 0.7 0.15 11.7 0.4 1.6 1 1 0 1 1 1 0 NEMP family HEAT_PBS PF03130.16 EKX32268.1 - 0.58 11.0 3.3 14 6.7 0.3 4.0 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Arm PF00514.23 EKX32268.1 - 4.7 7.4 8.3 76 3.6 2.6 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat MDD_C PF18376.1 EKX32269.1 - 6.6e-74 247.7 0.0 8.7e-74 247.3 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 EKX32269.1 - 7.8e-07 29.2 3.9 1.9e-06 28.0 3.9 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain PDZ_2 PF13180.6 EKX32270.1 - 0.056 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 PDZ domain COG2 PF06148.11 EKX32270.1 - 5.9 7.0 12.9 0.38 10.8 2.7 3.6 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4578 PF15147.6 EKX32270.1 - 9.4 7.1 7.0 45 4.9 0.8 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) PDZ_2 PF13180.6 EKX32271.1 - 2.2e-07 31.1 0.0 3.9e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX32271.1 - 0.00041 20.7 0.0 0.00085 19.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX32271.1 - 0.0044 17.0 0.0 0.0079 16.1 0.0 1.4 1 0 0 1 1 1 1 Tricorn protease PDZ domain PDZ_6 PF17820.1 EKX32271.1 - 0.0044 16.8 0.1 0.0078 16.0 0.1 1.5 1 0 0 1 1 1 1 PDZ domain SRX PF09201.10 EKX32271.1 - 0.13 12.1 0.1 0.32 10.8 0.0 1.6 2 0 0 2 2 2 0 SRX, signal recognition particle receptor alpha subunit Pap_E4 PF02711.14 EKX32273.1 - 5.1 8.1 7.3 6.6 7.8 2.1 2.2 2 0 0 2 2 2 0 E4 protein C2 PF00168.30 EKX32274.1 - 7.6e-09 35.8 0.0 1.7e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain BDV_P24 PF06595.11 EKX32275.1 - 0.092 12.6 0.4 0.12 12.2 0.4 1.1 1 0 0 1 1 1 0 Borna disease virus P24 protein Trimer_CC PF08954.11 EKX32275.1 - 0.12 11.9 3.2 0.23 11.0 1.2 2.1 1 1 1 2 2 2 0 Trimerisation motif adh_short PF00106.25 EKX32276.1 - 1.5e-26 93.1 0.0 1.9e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EKX32276.1 - 1.3e-20 74.0 0.0 1.9e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX32276.1 - 1.7e-07 31.3 0.0 2.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EKX32276.1 - 0.0047 16.8 0.0 0.0077 16.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EKX32276.1 - 0.11 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3972 PF13118.6 EKX32277.1 - 0.076 13.5 0.0 0.088 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) TPR_12 PF13424.6 EKX32278.1 - 1.4e-11 44.5 7.6 0.00041 20.6 0.2 4.0 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX32278.1 - 1.5e-10 40.4 1.6 0.013 15.3 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX32278.1 - 1.3e-09 37.5 5.8 0.18 12.0 0.1 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 EKX32278.1 - 4.8e-07 29.5 2.9 0.12 12.3 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX32278.1 - 0.0012 18.9 1.6 1.2 9.6 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX32278.1 - 0.0015 18.7 0.0 1.5 9.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX32278.1 - 0.009 16.8 5.8 16 6.6 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 EKX32278.1 - 0.013 15.7 0.1 0.73 10.2 0.0 2.9 2 0 0 2 2 2 0 PPR repeat TPR_4 PF07721.14 EKX32278.1 - 0.015 15.9 5.9 0.17 12.6 0.8 4.1 3 2 1 4 4 4 0 Tetratricopeptide repeat SPO22 PF08631.10 EKX32278.1 - 0.025 14.1 2.4 0.073 12.6 1.8 1.8 1 1 1 2 2 2 0 Meiosis protein SPO22/ZIP4 like TPR_16 PF13432.6 EKX32278.1 - 0.056 14.1 2.7 24 5.7 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat PolyA_pol_RNAbd PF12627.7 EKX32278.1 - 0.057 13.2 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A TPR_7 PF13176.6 EKX32278.1 - 0.13 12.3 8.6 7.1 6.9 0.1 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 EKX32278.1 - 0.31 11.2 4.8 1.1 9.4 0.1 3.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain OCRE PF17780.1 EKX32280.1 - 1.9 8.6 6.0 1.9 8.6 1.8 2.7 3 1 0 3 3 3 0 OCRE domain COX1 PF00115.20 EKX32281.1 - 2.9e-23 82.4 1.3 3.2e-23 82.3 1.3 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Peptidase_U32 PF01136.19 EKX32283.1 - 4.1e-90 301.0 0.0 3.3e-76 255.5 0.0 2.5 2 1 0 2 2 2 2 Peptidase family U32 DUF3656 PF12392.8 EKX32283.1 - 4.5e-15 56.2 0.0 9.3e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Collagenase Integrin_B_tail PF07965.12 EKX32283.1 - 0.34 11.4 4.8 0.33 11.5 1.0 2.2 2 0 0 2 2 2 0 Integrin beta tail domain WD40 PF00400.32 EKX32284.1 - 0.095 13.6 20.9 2.9 8.9 0.1 7.3 8 0 0 8 8 8 0 WD domain, G-beta repeat FXa_inhibition PF14670.6 EKX32284.1 - 0.2 12.0 0.7 0.42 10.9 0.7 1.5 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site WW PF00397.26 EKX32285.1 - 1.1e-10 41.4 1.1 2.3e-10 40.4 1.1 1.6 1 0 0 1 1 1 1 WW domain PRP1_N PF06424.12 EKX32285.1 - 2.5e-06 28.0 0.3 2.5e-06 28.0 0.3 1.7 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal Nop52 PF05997.12 EKX32286.1 - 3.2e-60 203.6 3.6 3.6e-60 203.4 3.6 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 IRF PF00605.17 EKX32286.1 - 0.046 14.0 0.7 0.079 13.3 0.7 1.4 1 0 0 1 1 1 0 Interferon regulatory factor transcription factor DUF3336 PF11815.8 EKX32286.1 - 0.062 13.0 0.4 0.11 12.2 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3336) NOG1_N PF17835.1 EKX32286.1 - 0.085 12.8 0.0 0.63 10.0 0.0 2.3 3 1 0 3 3 3 0 NOG1 N-terminal helical domain LRR_6 PF13516.6 EKX32287.1 - 3.2e-10 39.2 31.1 0.07 13.2 0.4 11.6 12 0 0 12 12 12 4 Leucine Rich repeat LRR_4 PF12799.7 EKX32287.1 - 7.3e-07 29.4 24.7 0.013 15.9 0.7 8.0 7 3 1 8 8 8 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX32287.1 - 0.00034 20.3 21.3 0.61 9.9 0.2 6.7 6 2 0 6 6 6 3 Leucine rich repeat F-box-like PF12937.7 EKX32287.1 - 0.32 10.9 4.3 1.1 9.1 4.3 2.0 1 0 0 1 1 1 0 F-box-like SnoaL_3 PF13474.6 EKX32288.1 - 4.2e-17 62.5 0.1 1.1e-16 61.2 0.0 1.7 2 0 0 2 2 2 1 SnoaL-like domain CaMKII_AD PF08332.10 EKX32288.1 - 0.0032 17.6 0.2 0.0063 16.7 0.2 1.6 1 1 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain SnoaL_2 PF12680.7 EKX32288.1 - 0.088 13.5 0.0 0.2 12.3 0.0 1.7 1 1 0 1 1 1 0 SnoaL-like domain SnoaL_4 PF13577.6 EKX32288.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like domain PEP-utilizers_C PF02896.18 EKX32289.1 - 2.2e-96 322.5 0.1 3.4e-96 321.8 0.1 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 EKX32289.1 - 2e-62 211.4 0.0 1.6e-46 159.1 0.0 3.1 1 1 1 2 2 2 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 EKX32289.1 - 4.6e-25 87.1 0.2 1.6e-24 85.4 0.2 2.0 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain CPBP PF02517.16 EKX32290.1 - 3.2e-16 59.5 5.9 3.2e-16 59.5 5.9 3.0 2 2 1 3 3 3 1 CPBP intramembrane metalloprotease Peptidase_C2 PF00648.21 EKX32293.1 - 9.6e-12 44.5 0.0 7.7e-11 41.5 0.0 2.2 2 0 0 2 2 2 1 Calpain family cysteine protease Collagen PF01391.18 EKX32294.1 - 9.4e-16 57.3 55.4 8e-09 35.1 28.2 2.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) tRNA-synt_2b PF00587.25 EKX32295.1 - 6.5e-41 140.3 0.0 1.1e-40 139.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EKX32295.1 - 1.2e-19 70.2 0.4 3.1e-19 68.9 0.4 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 EKX32295.1 - 7.2e-13 48.4 0.0 1.8e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Acetyltransf_4 PF13420.7 EKX32295.1 - 0.015 15.5 0.3 23 5.1 0.2 3.4 4 0 0 4 4 4 0 Acetyltransferase (GNAT) domain EF-hand_7 PF13499.6 EKX32297.1 - 0.12 12.9 0.4 0.23 11.9 0.2 1.6 2 1 0 2 2 2 0 EF-hand domain pair Y_phosphatase2 PF03162.13 EKX32298.1 - 2.7e-45 153.9 0.0 3.1e-45 153.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EKX32298.1 - 9.3e-06 25.8 0.1 1.2e-05 25.4 0.1 1.3 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EKX32298.1 - 0.00021 21.1 0.0 0.00025 20.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX32298.1 - 0.00042 20.0 0.0 0.0005 19.7 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX32298.1 - 0.032 14.3 0.0 0.048 13.8 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate DnaJ_C PF01556.18 EKX32300.1 - 3.2e-33 114.9 0.1 1.9e-32 112.4 0.1 2.0 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EKX32300.1 - 2.5e-24 85.2 1.8 4.4e-24 84.4 1.8 1.4 1 0 0 1 1 1 1 DnaJ domain DICT PF10069.9 EKX32301.1 - 0.082 12.7 0.0 0.099 12.4 0.0 1.1 1 0 0 1 1 1 0 Sensory domain in DIguanylate Cyclases and Two-component system PI3_PI4_kinase PF00454.27 EKX32302.1 - 1.4e-56 192.1 1.0 8e-56 189.6 0.1 2.5 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 EKX32302.1 - 5e-22 78.6 5.2 3e-20 72.7 5.2 2.3 1 1 0 1 1 1 1 FAT domain FATC PF02260.20 EKX32302.1 - 1.2e-13 50.6 0.5 3.3e-13 49.2 0.5 1.8 1 0 0 1 1 1 1 FATC domain DUF445 PF04286.12 EKX32302.1 - 0.022 14.6 0.0 0.056 13.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF445) ATP-grasp PF02222.22 EKX32302.1 - 0.037 13.6 0.0 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain HTH_57 PF18679.1 EKX32302.1 - 0.075 13.4 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 ThcOx helix turn helix domain Metallophos PF00149.28 EKX32305.1 - 1.9e-36 126.5 0.1 2.6e-36 126.0 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EKX32305.1 - 1.3e-19 70.4 0.2 2.2e-19 69.6 0.2 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Mito_carr PF00153.27 EKX32306.1 - 2.4e-06 27.4 0.1 9.4e-06 25.5 0.1 2.0 1 1 0 1 1 1 1 Mitochondrial carrier protein Mito_carr PF00153.27 EKX32307.1 - 4.9e-12 45.6 0.4 1.3e-09 37.9 0.4 2.1 1 1 0 1 1 1 1 Mitochondrial carrier protein HU-CCDC81_euk_1 PF14908.6 EKX32308.1 - 7.5e-13 48.5 1.3 1.8e-12 47.2 0.1 2.4 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 1 HU-CCDC81_euk_2 PF18289.1 EKX32308.1 - 7.6e-13 48.4 0.0 3.6e-11 43.0 0.0 2.8 3 0 0 3 3 3 1 CCDC81 eukaryotic HU domain 2 CLU_N PF15044.6 EKX32308.1 - 0.027 14.8 3.4 0.065 13.6 3.4 1.7 1 0 0 1 1 1 0 Mitochondrial function, CLU-N-term Spc29 PF17082.5 EKX32309.1 - 0.066 13.0 5.8 0.084 12.7 5.8 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 DUF3490 PF11995.8 EKX32309.1 - 2.2 8.1 8.6 3.9 7.3 8.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) MSP1a PF11670.8 EKX32309.1 - 2.6 7.3 5.7 0.68 9.2 2.1 1.7 2 0 0 2 2 2 0 Major surface protein 1a (MSP1a) DUF2924 PF11149.8 EKX32309.1 - 3.1 8.2 11.7 0.19 12.1 5.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2924) Glyco_transf_90 PF05686.12 EKX32310.1 - 7.2e-24 84.4 0.1 2.6e-23 82.6 0.1 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 EKX32310.1 - 0.053 13.9 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 fn3 PF00041.21 EKX32311.1 - 8.3e-20 70.9 11.9 0.013 15.8 0.3 10.9 9 1 0 9 9 9 6 Fibronectin type III domain EPTP PF03736.17 EKX32311.1 - 1e-09 38.2 5.2 9e-06 25.6 0.1 4.7 4 0 0 4 4 4 2 EPTP domain DUF2808 PF10989.8 EKX32311.1 - 0.0002 21.4 1.6 16 5.5 0.0 5.9 6 0 0 6 6 6 2 Protein of unknown function (DUF2808) LysM PF01476.20 EKX32311.1 - 0.0012 18.9 0.0 0.0058 16.7 0.0 2.2 1 0 0 1 1 1 1 LysM domain TIG PF01833.24 EKX32311.1 - 0.093 12.8 45.3 0.39 10.8 1.0 13.3 14 0 0 14 14 14 0 IPT/TIG domain Pkinase_Tyr PF07714.17 EKX32312.1 - 2.4e-66 223.7 0.0 2.7e-66 223.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX32312.1 - 4.8e-33 114.6 0.0 5.5e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain PARP PF00644.20 EKX32313.1 - 1.7e-23 83.3 2.2 4.8e-23 81.8 0.1 2.4 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain Exonuc_VII_L PF02601.15 EKX32313.1 - 1.4 8.4 6.5 1.8 8.1 6.5 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 EKX32313.1 - 4 5.2 6.3 5 4.9 6.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 EKX32313.1 - 6.8 6.5 14.8 2.3 8.1 11.4 1.9 1 1 1 2 2 2 0 Septum formation initiator OmpH PF03938.14 EKX32313.1 - 8.7 6.7 14.9 21 5.4 14.9 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) MCU PF04678.13 EKX32313.1 - 8.8 6.4 8.1 18 5.4 8.1 1.5 1 0 0 1 1 1 0 Mitochondrial calcium uniporter OstA PF03968.14 EKX32314.1 - 0.28 11.4 8.7 1.7e+02 2.5 0.0 3.7 2 1 0 2 2 2 0 OstA-like protein PB1 PF00564.24 EKX32316.1 - 0.0042 17.0 0.0 0.008 16.1 0.0 1.4 1 0 0 1 1 1 1 PB1 domain DUF2634 PF10934.8 EKX32317.1 - 0.14 12.3 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2634) CTP_transf_like PF01467.26 EKX32318.1 - 1.2e-16 61.2 0.0 2e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like CDP-OH_P_transf PF01066.21 EKX32318.1 - 4.5e-12 46.6 0.3 4.5e-12 46.6 0.3 3.1 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Guanylate_cyc PF00211.20 EKX32319.1 - 1.9e-20 73.3 0.0 2.8e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain GBP PF02263.19 EKX32320.1 - 3.9e-13 49.3 2.4 2.3e-07 30.4 0.2 2.0 1 1 1 2 2 2 2 Guanylate-binding protein, N-terminal domain PIF1 PF05970.14 EKX32320.1 - 0.077 12.1 0.1 0.077 12.1 0.1 1.1 1 0 0 1 1 1 0 PIF1-like helicase LptF_LptG PF03739.14 EKX32320.1 - 0.084 11.7 0.0 0.1 11.4 0.0 1.0 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG HECT PF00632.25 EKX32321.1 - 3.2e-39 135.2 0.0 3.5e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PDZ_6 PF17820.1 EKX32322.1 - 2.6e-08 33.6 0.0 6.7e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX32322.1 - 2.7e-07 30.9 0.0 5.7e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX32322.1 - 0.00015 22.0 0.0 0.00037 20.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX32322.1 - 0.067 13.2 0.0 0.64 10.0 0.0 2.5 1 1 0 1 1 1 0 Tricorn protease PDZ domain polyprenyl_synt PF00348.17 EKX32323.1 - 3.7e-78 262.1 0.0 4.8e-78 261.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase ABC_tran PF00005.27 EKX32324.1 - 6.5e-25 88.2 0.0 2.6e-24 86.3 0.0 2.0 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EKX32324.1 - 1.9e-24 86.4 13.9 1.9e-24 86.4 13.9 2.8 3 0 0 3 3 3 1 ABC-2 family transporter protein AAA_21 PF13304.6 EKX32324.1 - 1.2e-10 41.7 0.2 4.1e-07 30.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 EKX32324.1 - 4.3e-05 23.0 15.4 4.3e-05 23.0 15.4 2.7 3 0 0 3 3 3 2 ABC-2 type transporter AAA_23 PF13476.6 EKX32324.1 - 0.004 17.7 0.8 0.0076 16.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain Chitin_bind_4 PF00379.23 EKX32324.1 - 0.0097 16.4 0.0 0.24 11.9 0.0 2.6 2 0 0 2 2 2 1 Insect cuticle protein DUF4162 PF13732.6 EKX32324.1 - 0.092 13.5 0.0 0.37 11.5 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) AAA_15 PF13175.6 EKX32324.1 - 0.13 11.9 0.0 2.6 7.7 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain SMC_N PF02463.19 EKX32324.1 - 0.15 11.5 0.0 3 7.2 0.0 2.3 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain CagX PF03524.15 EKX32324.1 - 0.17 11.6 0.8 0.33 10.6 0.8 1.4 1 0 0 1 1 1 0 Conjugal transfer protein Bro-N PF02498.17 EKX32325.1 - 3.3e-06 27.7 0.2 3.3e-06 27.7 0.2 2.2 2 0 0 2 2 2 1 BRO family, N-terminal domain RasGEF_N PF00618.20 EKX32325.1 - 0.49 10.7 2.6 0.51 10.6 0.1 2.1 2 0 0 2 2 2 0 RasGEF N-terminal motif SMYLE_N PF18615.1 EKX32325.1 - 0.9 9.0 5.9 1.3 8.5 5.9 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Pex14_N PF04695.13 EKX32325.1 - 1.9 9.1 9.9 1.5 9.4 7.8 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RRP14 PF15459.6 EKX32325.1 - 2.8 8.6 7.0 10 6.8 5.5 2.5 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 Presenilin PF01080.17 EKX32325.1 - 4.3 6.0 4.8 5.9 5.5 4.8 1.2 1 0 0 1 1 1 0 Presenilin SMC_N PF02463.19 EKX32327.1 - 0.00034 20.1 0.0 0.00065 19.2 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EKX32327.1 - 0.00044 20.4 0.0 0.00097 19.3 0.0 1.6 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit FliJ PF02050.16 EKX32327.1 - 0.016 15.4 2.2 0.016 15.4 2.2 5.5 4 2 2 6 6 5 0 Flagellar FliJ protein SAB PF04382.13 EKX32327.1 - 0.12 12.5 2.3 0.21 11.7 0.0 2.7 3 0 0 3 3 3 0 SAB domain NPV_P10 PF05531.12 EKX32327.1 - 0.52 10.8 39.4 6.2 7.4 1.7 8.1 5 2 2 7 7 7 0 Nucleopolyhedrovirus P10 protein Turandot PF07240.11 EKX32327.1 - 0.61 10.1 2.5 3.3 7.7 2.5 2.3 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot Seryl_tRNA_N PF02403.22 EKX32327.1 - 0.9 9.8 26.1 6.1 7.1 0.1 6.3 7 0 0 7 7 7 0 Seryl-tRNA synthetase N-terminal domain DUF948 PF06103.11 EKX32327.1 - 2.3 8.5 14.3 29 5.0 2.1 5.4 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) HrpB7 PF09486.10 EKX32327.1 - 2.4 8.6 15.0 10 6.5 2.6 3.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Med9 PF07544.13 EKX32327.1 - 4.2 7.5 25.0 0.78 9.9 7.0 5.4 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 WXG100 PF06013.12 EKX32327.1 - 8.3 6.7 23.4 6.3 7.1 1.4 6.9 7 0 0 7 7 7 0 Proteins of 100 residues with WXG DASH_Duo1 PF08651.10 EKX32327.1 - 8.5 6.2 14.3 3 7.7 0.6 5.5 6 0 0 6 6 6 0 DASH complex subunit Duo1 FAA_hydro_N_2 PF18288.1 EKX32327.1 - 8.7 6.9 9.1 3.1 8.3 0.1 4.5 5 0 0 5 5 5 0 Fumarylacetoacetase N-terminal domain 2 Anp1 PF03452.14 EKX32328.1 - 0.0019 17.6 0.0 0.0041 16.6 0.0 1.5 2 0 0 2 2 2 1 Anp1 PAS_11 PF14598.6 EKX32330.1 - 0.073 13.2 0.3 0.16 12.1 0.3 1.6 1 0 0 1 1 1 0 PAS domain RNA_pol_Rpb6 PF01192.22 EKX32330.1 - 2.5 8.1 6.4 29 4.7 0.1 3.8 3 1 1 4 4 4 0 RNA polymerase Rpb6 GFO_IDH_MocA PF01408.22 EKX32331.1 - 1.6e-10 41.8 0.0 2.2e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold FAD_binding_4 PF01565.23 EKX32332.1 - 5.4e-18 65.1 0.1 9.3e-18 64.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain BSD PF03909.17 EKX32333.1 - 7.5e-11 41.9 0.4 2.3e-10 40.3 0.2 1.9 1 1 1 2 2 2 1 BSD domain Mito_carr PF00153.27 EKX32334.1 - 1.9e-36 123.9 2.5 1.5e-15 56.8 0.3 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Ank_2 PF12796.7 EKX32335.1 - 1.9e-10 41.2 0.0 2.9e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX32335.1 - 4.7e-10 39.5 0.1 1.2e-09 38.2 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX32335.1 - 2.4e-09 37.2 0.1 2.9e-05 24.3 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EKX32335.1 - 4e-07 29.8 0.0 0.00042 20.5 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EKX32335.1 - 1.2e-05 25.7 0.1 6e-05 23.5 0.1 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) SecA_DEAD PF07517.14 EKX32338.1 - 1.3e-121 405.4 0.3 2.4e-121 404.5 0.3 1.4 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.13 EKX32338.1 - 8.4e-43 146.8 3.4 8.4e-43 146.8 3.4 2.4 3 0 0 3 3 3 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 EKX32338.1 - 7.7e-35 119.9 0.0 2.8e-34 118.1 0.0 2.0 1 0 0 1 1 1 1 SecA preprotein cross-linking domain DEAD PF00270.29 EKX32338.1 - 1.1e-06 28.6 0.6 2.4e-05 24.2 0.0 2.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase YvrJ PF12841.7 EKX32338.1 - 0.0093 15.5 0.8 0.0093 15.5 0.8 1.8 2 0 0 2 2 2 1 YvrJ protein family BcrAD_BadFG PF01869.20 EKX32338.1 - 0.025 14.1 0.1 0.31 10.5 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DUF3071 PF11268.8 EKX32338.1 - 0.053 13.6 0.4 0.68 10.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3071) ResIII PF04851.15 EKX32338.1 - 0.17 11.9 1.4 0.61 10.1 0.2 2.5 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EKX32338.1 - 0.4 11.0 1.4 11 6.4 0.0 3.0 3 0 0 3 3 3 0 Helicase conserved C-terminal domain EF-hand_7 PF13499.6 EKX32339.1 - 4.4e-14 52.7 0.0 5e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX32339.1 - 7.4e-14 50.2 0.1 8.6e-06 24.9 0.0 2.5 2 1 1 3 3 3 2 EF hand EF-hand_8 PF13833.6 EKX32339.1 - 2.5e-13 49.6 0.1 6.9e-10 38.6 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX32339.1 - 9e-13 47.1 0.1 8.6e-07 28.4 0.0 2.7 1 1 2 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 EKX32339.1 - 1.3e-09 37.1 0.8 0.0029 17.0 0.0 3.1 2 1 1 3 3 3 3 EF hand DUF5580 PF17743.1 EKX32339.1 - 0.0002 20.1 0.0 0.0002 20.0 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) Caleosin PF05042.13 EKX32339.1 - 0.0051 16.8 0.1 1 9.2 0.0 2.0 1 1 1 2 2 2 2 Caleosin related protein EF-hand_4 PF12763.7 EKX32339.1 - 0.012 15.6 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand FGAR-AT_linker PF18072.1 EKX32339.1 - 0.032 14.8 0.3 2 9.0 0.1 2.5 1 1 1 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain DUF2604 PF10790.9 EKX32339.1 - 0.19 12.0 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of Unknown function (DUF2604) ABC2_membrane PF01061.24 EKX32340.1 - 4.8e-53 179.7 60.3 2.4e-28 99.0 23.7 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EKX32340.1 - 1.5e-38 132.4 0.0 1.6e-18 67.5 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 EKX32340.1 - 4.7e-07 29.4 0.4 0.009 15.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EKX32340.1 - 1.1e-06 29.1 0.0 0.078 13.4 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 EKX32340.1 - 1.6e-06 28.2 0.0 0.11 12.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EKX32340.1 - 3.3e-05 23.6 1.3 0.33 10.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EKX32340.1 - 4.1e-05 23.5 0.5 0.0051 16.7 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EKX32340.1 - 5.5e-05 23.5 0.2 0.27 11.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.7 EKX32340.1 - 0.00058 19.1 47.3 0.0076 15.4 22.1 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein Glucan_synthase PF02364.15 EKX32340.1 - 0.00072 17.9 1.1 0.00072 17.9 1.1 1.8 2 0 0 2 2 2 1 1,3-beta-glucan synthase component MMR_HSR1 PF01926.23 EKX32340.1 - 0.0016 18.5 0.0 2 8.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.29 EKX32340.1 - 0.0021 18.5 0.3 5.4 7.5 0.1 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 EKX32340.1 - 0.0022 17.5 0.0 4.2 6.8 0.0 3.3 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 EKX32340.1 - 0.0022 18.6 0.0 1.2 9.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EKX32340.1 - 0.0038 17.0 0.1 0.25 11.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EKX32340.1 - 0.0042 17.0 0.5 3.4 7.6 0.3 2.4 2 0 0 2 2 2 2 NACHT domain AAA_14 PF13173.6 EKX32340.1 - 0.0078 16.3 0.0 1.2 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EKX32340.1 - 0.0089 16.0 0.5 1.6 8.6 0.0 3.1 3 0 0 3 3 3 1 NTPase RNA_helicase PF00910.22 EKX32340.1 - 0.011 16.1 0.0 2.4 8.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 EKX32340.1 - 0.013 15.7 2.3 4.3 7.6 0.5 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EKX32340.1 - 0.019 15.1 0.0 7.3 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EKX32340.1 - 0.024 15.2 0.4 0.4 11.2 0.1 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EKX32340.1 - 0.035 13.4 0.1 2.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin SbcCD_C PF13558.6 EKX32340.1 - 0.071 13.4 0.0 0.42 10.9 0.0 2.3 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.9 EKX32340.1 - 0.08 12.7 0.4 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RuvB_N PF05496.12 EKX32340.1 - 0.12 12.1 0.2 17 5.2 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 EKX32340.1 - 0.17 11.6 1.2 16 5.2 0.2 2.6 3 0 0 3 3 2 0 AAA domain AAA_17 PF13207.6 EKX32340.1 - 0.19 12.1 0.7 1.1e+02 3.1 0.0 3.5 3 1 0 3 3 3 0 AAA domain AAA_19 PF13245.6 EKX32340.1 - 0.23 11.8 0.5 13 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF5313 PF17240.2 EKX32340.1 - 6.8 7.2 5.4 41 4.6 0.3 3.1 2 0 0 2 2 2 0 Family of unknown function (DUF5313) CK2S PF15011.6 EKX32341.1 - 0.06 13.2 0.0 0.069 13.0 0.0 1.1 1 0 0 1 1 1 0 Casein Kinase 2 substrate zf-C4 PF00105.18 EKX32342.1 - 0.003 18.0 3.3 2.1 8.9 0.3 2.7 2 0 0 2 2 2 2 Zinc finger, C4 type (two domains) SapA PF02199.15 EKX32342.1 - 0.039 14.2 1.4 11 6.5 0.1 2.4 2 0 0 2 2 2 0 Saposin A-type domain CAP-ZIP_m PF15255.6 EKX32342.1 - 0.11 12.8 2.8 12 6.2 0.2 2.7 2 0 0 2 2 2 0 WASH complex subunit CAP-Z interacting, central region Aa_trans PF01490.18 EKX32344.1 - 3.3e-23 82.1 27.7 4.3e-23 81.7 27.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1129 PF06570.11 EKX32344.1 - 7.9 5.9 6.8 0.67 9.4 1.4 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) FYRC PF05965.14 EKX32345.1 - 0.28 11.4 1.1 0.85 9.8 0.2 2.1 2 0 0 2 2 2 0 F/Y rich C-terminus PKD_channel PF08016.12 EKX32346.1 - 1.1e-25 90.2 18.8 2.5e-17 62.7 14.2 2.7 3 0 0 3 3 3 2 Polycystin cation channel C2 PF00168.30 EKX32346.1 - 5.3e-23 81.3 0.0 1.1e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain Ion_trans PF00520.31 EKX32346.1 - 6.8e-11 41.9 23.0 3.8e-10 39.4 23.0 2.1 1 1 0 1 1 1 1 Ion transport protein Toxin_11 PF07473.11 EKX32346.1 - 0.03 14.4 1.6 0.11 12.5 1.6 2.0 1 0 0 1 1 1 0 Spasmodic peptide gm9a; conotoxin from Conus species Macoilin PF09726.9 EKX32346.1 - 0.094 11.3 0.3 0.16 10.5 0.3 1.2 1 0 0 1 1 1 0 Macoilin family EF-hand_5 PF13202.6 EKX32346.1 - 0.13 11.9 0.0 0.36 10.4 0.0 1.8 1 0 0 1 1 1 0 EF hand IL2 PF00715.17 EKX32346.1 - 0.18 11.8 0.6 1.8 8.5 0.1 2.7 3 0 0 3 3 3 0 Interleukin 2 PKD_channel PF08016.12 EKX32347.1 - 3.9e-25 88.4 19.2 4.4e-17 61.9 14.6 2.7 3 0 0 3 3 3 2 Polycystin cation channel C2 PF00168.30 EKX32347.1 - 1.3e-21 76.8 0.0 3.1e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain Ion_trans PF00520.31 EKX32347.1 - 2.3e-09 36.9 22.8 1.2e-08 34.5 22.8 2.0 1 1 0 1 1 1 1 Ion transport protein Toxin_11 PF07473.11 EKX32347.1 - 0.062 13.4 1.4 0.22 11.6 1.4 2.0 1 0 0 1 1 1 0 Spasmodic peptide gm9a; conotoxin from Conus species EF-hand_5 PF13202.6 EKX32347.1 - 0.16 11.5 0.0 0.39 10.3 0.0 1.6 1 0 0 1 1 1 0 EF hand Laminin_B PF00052.18 EKX32348.1 - 8.6e-12 45.1 0.0 2.9e-11 43.4 0.0 2.0 2 0 0 2 2 2 1 Laminin B (Domain IV) TIG PF01833.24 EKX32348.1 - 1.8e-06 27.9 4.9 7.9e-06 25.9 0.0 4.5 3 0 0 3 3 3 1 IPT/TIG domain KOW PF00467.29 EKX32348.1 - 0.012 15.6 1.0 7.4 6.7 0.0 4.2 4 0 0 4 4 4 0 KOW motif HATPase_c_3 PF13589.6 EKX32349.1 - 0.00021 21.1 0.0 0.00063 19.6 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EKX32349.1 - 0.1 12.6 0.0 0.33 10.9 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Filamin PF00630.19 EKX32349.1 - 0.14 13.0 1.1 4.5 8.2 0.0 3.7 3 1 0 3 3 3 0 Filamin/ABP280 repeat HATPase_c PF02518.26 EKX32349.1 - 0.18 12.3 0.1 4.6 7.8 0.0 2.8 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-MYND PF01753.18 EKX32350.1 - 0.00015 21.8 18.1 0.00015 21.8 18.1 1.8 2 0 0 2 2 2 1 MYND finger CDC45 PF02724.14 EKX32350.1 - 1.4 7.1 4.0 1.8 6.7 4.0 1.1 1 0 0 1 1 1 0 CDC45-like protein tRNA-synt_1e PF01406.19 EKX32351.1 - 2.5e-112 375.1 0.0 3.3e-112 374.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EKX32351.1 - 7e-11 41.5 0.0 3.6e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 EKX32351.1 - 7.1e-06 25.2 0.0 0.045 12.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) DALR_2 PF09190.11 EKX32351.1 - 2e-05 25.0 0.0 6.4e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 DALR domain tRNA-synt_1c PF00749.21 EKX32351.1 - 0.0029 16.6 1.7 0.0087 15.0 0.0 2.3 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), catalytic domain Pox_Ag35 PF03286.14 EKX32352.1 - 0.93 9.3 9.6 5 6.9 5.4 2.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein PDZ PF00595.24 EKX32353.1 - 7.1e-10 39.1 0.7 2.6e-09 37.3 0.5 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EKX32353.1 - 1.4e-09 37.6 0.5 4e-09 36.2 0.5 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX32353.1 - 3.6e-06 27.2 0.0 8.2e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 EKX32353.1 - 0.00015 22.1 0.0 0.001 19.4 0.0 2.2 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain HALZ PF02183.18 EKX32353.1 - 0.012 15.8 0.8 0.072 13.3 0.4 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper Syntaxin-6_N PF09177.11 EKX32353.1 - 0.043 14.4 10.1 0.43 11.2 2.5 2.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Tricorn_PDZ PF14685.6 EKX32353.1 - 0.072 13.1 0.0 0.18 11.8 0.0 1.7 1 1 0 1 1 1 0 Tricorn protease PDZ domain NYD-SP28_assoc PF14775.6 EKX32353.1 - 0.6 10.2 3.4 2.5 8.2 2.4 2.7 2 1 0 2 2 2 0 Sperm tail C-terminal domain Cnn_1N PF07989.11 EKX32353.1 - 1.4 9.1 14.4 0.07 13.3 2.5 3.4 1 1 3 4 4 4 0 Centrosomin N-terminal motif 1 IKKbetaNEMObind PF12179.8 EKX32353.1 - 4 7.6 8.2 4.4 7.4 2.8 3.3 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain Abhydrolase_1 PF00561.20 EKX32354.1 - 0.00029 20.6 0.1 0.00031 20.5 0.1 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EKX32354.1 - 0.00057 20.6 0.2 0.00064 20.4 0.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family SoPB_HTH PF18090.1 EKX32354.1 - 0.05 13.7 0.2 0.15 12.2 0.2 1.7 1 1 0 1 1 1 0 Centromere-binding protein HTH domain RraA-like PF03737.15 EKX32355.1 - 3.4e-42 144.1 0.2 4.1e-42 143.9 0.2 1.1 1 0 0 1 1 1 1 Aldolase/RraA LCM PF04072.14 EKX32356.1 - 3.7e-17 62.9 0.0 8.7e-16 58.4 0.0 2.9 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase TTL PF03133.15 EKX32357.1 - 9.5e-54 182.5 0.0 1.2e-53 182.1 0.0 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EKX32357.1 - 0.00017 21.0 0.1 0.00037 19.8 0.0 1.7 1 1 1 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EKX32357.1 - 0.061 12.6 0.0 0.088 12.0 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp CaMBD PF02888.16 EKX32358.1 - 0.097 12.9 0.2 0.26 11.5 0.2 1.7 1 0 0 1 1 1 0 Calmodulin binding domain Dynactin_p62 PF05502.13 EKX32358.1 - 0.5 9.1 6.4 1.1 8.0 6.4 1.5 1 0 0 1 1 1 0 Dynactin p62 family YlbD_coat PF14071.6 EKX32359.1 - 0.52 10.6 12.3 10 6.4 12.3 2.0 1 1 0 1 1 1 0 Putative coat protein EF-hand_7 PF13499.6 EKX32360.1 - 0.0022 18.4 0.1 0.0044 17.5 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX32360.1 - 0.0047 16.7 0.4 0.0099 15.7 0.4 1.5 1 0 0 1 1 1 1 EF-hand domain DLEU7 PF15760.5 EKX32360.1 - 0.042 13.3 0.6 0.073 12.6 0.6 1.3 1 0 0 1 1 1 0 Leukemia-associated protein 7 PAC4 PF16093.5 EKX32361.1 - 8.8e-21 73.9 0.1 1.2e-20 73.5 0.1 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 PhoLip_ATPase_C PF16212.5 EKX32362.1 - 4.9e-73 246.0 19.7 4.9e-73 246.0 19.7 1.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EKX32362.1 - 7.7e-22 76.8 0.6 1.9e-21 75.5 0.6 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EKX32362.1 - 1.4e-07 32.0 0.0 0.19 12.0 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EKX32362.1 - 2.1e-06 27.7 0.0 1.8e-05 24.7 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EKX32362.1 - 0.00046 20.0 0.1 0.00093 19.0 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EKX32362.1 - 0.047 13.2 2.7 0.17 11.4 0.1 2.9 2 1 0 2 2 2 0 E1-E2 ATPase CDC50 PF03381.15 EKX32363.1 - 7.1e-48 163.5 0.2 8.6e-48 163.3 0.2 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Spore_II_R PF09551.10 EKX32364.1 - 0.057 13.9 1.5 0.1 13.0 0.3 2.1 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) DUF2040 PF09745.9 EKX32365.1 - 7.5e-15 55.1 8.9 9.5e-15 54.7 8.9 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 55 (DUF2040) Peptidase_M32 PF02074.15 EKX32365.1 - 0.058 12.1 1.5 0.064 12.0 1.5 1.0 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase DUF3896 PF13035.6 EKX32366.1 - 0.53 10.5 4.6 2.3 8.4 1.2 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) fn2 PF00040.19 EKX32366.1 - 2.2 8.6 8.8 0.74 10.1 4.1 2.4 2 0 0 2 2 2 0 Fibronectin type II domain FAM60A PF15396.6 EKX32367.1 - 0.024 14.6 32.5 0.03 14.3 32.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Presenilin PF01080.17 EKX32367.1 - 0.089 11.5 53.7 0.096 11.4 53.7 1.1 1 0 0 1 1 1 0 Presenilin XRN_M PF17846.1 EKX32367.1 - 2.9 6.7 36.5 3.1 6.6 36.5 1.0 1 0 0 1 1 1 0 Xrn1 helical domain SLC12 PF03522.15 EKX32367.1 - 3.8 6.4 51.2 4.3 6.3 51.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF572 PF04502.13 EKX32367.1 - 4 7.0 40.6 4.8 6.7 40.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) WTX PF09422.10 EKX32367.1 - 5.8 5.9 32.4 7.4 5.5 32.4 1.2 1 0 0 1 1 1 0 WTX protein CDC45 PF02724.14 EKX32368.1 - 0.004 15.5 10.9 0.0037 15.6 10.9 1.0 1 0 0 1 1 1 1 CDC45-like protein DDHD PF02862.17 EKX32368.1 - 0.013 15.7 2.2 0.012 15.8 2.2 1.2 1 0 0 1 1 1 0 DDHD domain Paf1 PF03985.13 EKX32368.1 - 0.065 12.2 17.7 0.075 12.0 17.7 1.0 1 0 0 1 1 1 0 Paf1 DUF913 PF06025.12 EKX32368.1 - 0.1 11.6 3.3 0.1 11.6 3.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) UPF0560 PF10577.9 EKX32368.1 - 0.1 11.1 9.6 0.12 10.8 9.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TEX19 PF15553.6 EKX32368.1 - 0.11 12.5 4.9 0.13 12.2 4.9 1.2 1 0 0 1 1 1 0 Testis-expressed protein 19 Nop14 PF04147.12 EKX32368.1 - 0.11 10.6 14.2 0.13 10.4 14.2 1.0 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 EKX32368.1 - 0.12 12.2 8.9 0.16 11.8 8.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EPL1 PF10513.9 EKX32368.1 - 0.12 12.7 12.8 0.16 12.3 12.8 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like Suf PF05843.14 EKX32368.1 - 0.13 12.2 5.7 0.15 12.1 5.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 EKX32368.1 - 0.22 11.1 24.7 0.28 10.8 24.7 1.1 1 0 0 1 1 1 0 Spt20 family Neur_chan_memb PF02932.16 EKX32368.1 - 0.24 11.4 1.9 0.23 11.5 1.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AAA_23 PF13476.6 EKX32368.1 - 0.27 11.7 11.0 0.3 11.6 11.0 1.1 1 0 0 1 1 1 0 AAA domain SDA1 PF05285.12 EKX32368.1 - 0.28 10.6 17.4 0.33 10.3 17.4 1.1 1 0 0 1 1 1 0 SDA1 MCM_bind PF09739.9 EKX32368.1 - 0.3 9.5 12.3 0.35 9.3 12.3 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Hid1 PF12722.7 EKX32368.1 - 0.39 8.8 6.9 0.4 8.8 6.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein EIIBC-GUT_N PF03612.14 EKX32368.1 - 0.41 10.4 8.0 0.51 10.1 8.0 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CobT PF06213.12 EKX32368.1 - 0.42 10.0 24.8 0.56 9.6 24.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Presenilin PF01080.17 EKX32368.1 - 0.45 9.2 10.1 0.52 9.0 10.1 1.1 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 EKX32368.1 - 0.56 10.4 9.0 0.69 10.1 9.0 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Gti1_Pac2 PF09729.9 EKX32368.1 - 0.59 10.2 6.9 0.79 9.8 6.9 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Ureide_permease PF07168.11 EKX32368.1 - 0.64 8.7 1.7 0.71 8.6 1.7 1.1 1 0 0 1 1 1 0 Ureide permease Cwf_Cwc_15 PF04889.12 EKX32368.1 - 0.73 9.5 18.9 1.2 8.9 18.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Connexin PF00029.19 EKX32368.1 - 0.81 9.4 7.4 0.9 9.2 7.4 1.1 1 0 0 1 1 1 0 Connexin XAP5 PF04921.14 EKX32368.1 - 0.83 9.4 12.7 1.1 9.0 12.7 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator Pex14_N PF04695.13 EKX32368.1 - 0.94 10.1 12.0 0.15 12.7 8.5 1.4 2 0 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NOA36 PF06524.12 EKX32368.1 - 1.2 8.4 15.4 1.5 8.1 15.4 1.2 1 0 0 1 1 1 0 NOA36 protein TFB6 PF17110.5 EKX32368.1 - 1.2 8.8 10.3 1.7 8.4 10.3 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF4175 PF13779.6 EKX32368.1 - 1.2 6.9 22.0 1.5 6.7 22.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF2722 PF10846.8 EKX32368.1 - 2.1 7.2 25.9 2.9 6.8 25.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIF_alpha PF05793.12 EKX32368.1 - 2.1 6.8 19.4 2.8 6.4 19.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4589 PF15252.6 EKX32368.1 - 2.3 8.2 11.3 3.7 7.5 11.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) AIF_C PF14721.6 EKX32368.1 - 2.6 8.4 8.9 3.6 7.9 8.9 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Coilin_N PF15862.5 EKX32368.1 - 2.7 7.8 14.4 4.3 7.1 14.4 1.3 1 0 0 1 1 1 0 Coilin N-terminus PTPRCAP PF15713.5 EKX32368.1 - 2.7 8.3 21.7 4 7.7 21.7 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF4834 PF16118.5 EKX32368.1 - 2.7 9.0 10.2 4.2 8.4 10.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF1980 PF09323.10 EKX32368.1 - 3.6 7.5 5.7 4.1 7.3 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) SpoIIP PF07454.11 EKX32368.1 - 3.7 6.9 14.2 4.8 6.6 14.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Serinc PF03348.15 EKX32368.1 - 4.5 6.1 4.4 4.8 6.0 4.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) G0-G1_switch_2 PF15103.6 EKX32368.1 - 5.2 7.6 8.2 7.5 7.0 8.2 1.3 1 0 0 1 1 1 0 G0/G1 switch protein 2 TERB2 PF15101.6 EKX32368.1 - 5.4 7.0 15.1 6.6 6.7 15.1 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 RNase_H2_suC PF08615.11 EKX32368.1 - 5.5 7.2 11.0 28 4.9 11.0 1.9 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF3464 PF11947.8 EKX32368.1 - 5.8 6.7 9.1 8 6.2 9.1 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 V_ATPase_I PF01496.19 EKX32368.1 - 7 4.4 11.2 8 4.2 11.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zip PF02535.22 EKX32368.1 - 7.7 5.6 7.5 9.3 5.4 7.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Sec62 PF03839.16 EKX32368.1 - 9.6 5.7 6.7 12 5.3 6.7 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4407 PF14362.6 EKX32368.1 - 9.9 5.4 10.8 11 5.2 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DEAD PF00270.29 EKX32369.1 - 2.2e-40 138.3 0.0 5.9e-40 136.9 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EKX32369.1 - 0.0058 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DnaJ PF00226.31 EKX32370.1 - 1.4e-26 92.3 3.6 1.6e-26 92.2 3.6 1.0 1 0 0 1 1 1 1 DnaJ domain DUF4460 PF14687.6 EKX32370.1 - 0.012 15.6 0.8 0.013 15.5 0.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) Thioredoxin PF00085.20 EKX32371.1 - 1.7e-10 40.8 0.2 1.8e-10 40.7 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin DUF2315 PF10231.9 EKX32373.1 - 0.058 13.5 0.1 0.058 13.5 0.1 1.9 2 0 0 2 2 2 0 Apoptogenic protein 1 SAM_2 PF07647.17 EKX32373.1 - 0.14 12.3 0.0 0.58 10.3 0.0 2.0 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) DUF2070 PF09843.9 EKX32373.1 - 4.9 5.3 12.7 7.2 4.8 12.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RWP-RK PF02042.15 EKX32375.1 - 2.5e-14 53.0 0.0 3.4e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX32375.1 - 0.15 11.9 0.1 1.7 8.5 0.0 2.1 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family Oxysterol_BP PF01237.18 EKX32377.1 - 2.3e-15 56.3 0.1 2.3e-12 46.5 1.3 2.0 2 0 0 2 2 2 2 Oxysterol-binding protein TRAPPC9-Trs120 PF08626.11 EKX32378.1 - 3.2e-19 67.9 0.0 2.4e-09 35.2 0.0 3.6 3 1 0 4 4 4 3 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit GREB1 PF15782.5 EKX32379.1 - 5.6e-17 60.3 0.1 4.5e-08 30.8 0.0 7.1 5 2 4 9 9 9 4 Gene regulated by oestrogen in breast cancer RAMA PF18755.1 EKX32379.1 - 0.00079 19.8 0.2 0.0037 17.6 0.2 2.2 1 0 0 1 1 1 1 Restriction Enzyme Adenine Methylase Associated CBM_20 PF00686.19 EKX32380.1 - 5.2e-15 55.1 0.0 9.4e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 Starch binding domain DUF2009 PF09418.10 EKX32381.1 - 1.3e-202 673.9 0.0 1.5e-202 673.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 EKX32381.1 - 0.0013 18.8 3.4 0.0026 17.8 3.4 1.5 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 EKX32381.1 - 0.0055 16.9 2.9 0.012 15.8 2.9 1.6 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-HIT PF04438.16 EKX32381.1 - 0.12 12.3 3.8 0.23 11.3 3.8 1.5 1 0 0 1 1 1 0 HIT zinc finger IBR PF01485.21 EKX32381.1 - 1.2 9.4 8.6 3.4 8.0 7.4 2.3 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Proteasome PF00227.26 EKX32382.1 - 4.8e-33 114.3 0.0 5.8e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Ephrin_rec_like PF07699.13 EKX32386.1 - 6.3e-37 125.1 113.5 4.4e-07 29.6 8.0 7.6 2 2 8 10 10 10 10 Putative ephrin-receptor like NCD3G PF07562.14 EKX32386.1 - 1.1e-08 35.0 62.8 0.011 15.7 0.8 8.6 3 2 6 11 11 11 7 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX32386.1 - 0.0003 21.1 67.8 0.014 15.8 7.8 9.0 3 1 6 9 9 9 7 TNFR/NGFR cysteine-rich region RANK_CRD_2 PF18278.1 EKX32386.1 - 1.4 9.2 22.6 0.54 10.5 2.9 4.8 3 2 0 3 3 3 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 CAF20 PF17052.5 EKX32387.1 - 0.086 13.0 1.0 0.13 12.5 0.2 1.6 2 0 0 2 2 2 0 Cap associated factor OAM_alpha PF16552.5 EKX32388.1 - 0.1 12.5 0.2 0.16 11.8 0.2 1.3 1 0 0 1 1 1 0 D-ornithine 4,5-aminomutase alpha-subunit SSP160 PF06933.11 EKX32388.1 - 0.22 9.7 7.7 0.27 9.4 7.7 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF481 PF04338.12 EKX32389.1 - 0.077 13.0 0.9 0.19 11.8 0.9 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF481 DUF3078 PF11276.8 EKX32389.1 - 0.19 12.2 1.8 2.9 8.4 1.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3078) DUF1943 PF09172.11 EKX32389.1 - 1.2 8.2 8.9 12 5.0 8.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1943) RWP-RK PF02042.15 EKX32390.1 - 2.8e-09 36.8 0.4 5.6e-09 35.8 0.4 1.4 1 0 0 1 1 1 1 RWP-RK domain Gly-zipper_OmpA PF13436.6 EKX32390.1 - 0.19 11.5 21.7 1.8e+04 -10.7 21.5 5.4 1 1 0 1 1 1 0 Glycine-zipper domain CAP_GLY PF01302.25 EKX32390.1 - 1.7 8.7 45.2 11 6.2 1.2 9.3 1 1 7 8 8 8 0 CAP-Gly domain PT PF04886.12 EKX32391.1 - 1.6e-07 30.7 5.5 5.8e-07 28.9 5.5 1.8 1 1 0 1 1 1 1 PT repeat CAP_GLY PF01302.25 EKX32391.1 - 0.033 14.2 8.8 6.5 6.9 0.2 3.8 1 1 1 2 2 2 0 CAP-Gly domain DUF1943 PF09172.11 EKX32393.1 - 2.6e-05 23.6 15.4 0.00093 18.5 7.9 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1943) PorP_SprF PF11751.8 EKX32393.1 - 0.0022 17.6 0.3 0.0068 16.0 0.3 1.8 1 1 0 1 1 1 1 Type IX secretion system membrane protein PorP/SprF OMP_b-brl_2 PF13568.6 EKX32393.1 - 0.0079 16.2 0.4 0.39 10.7 0.4 2.8 1 1 1 2 2 2 2 Outer membrane protein beta-barrel domain MspA PF09203.11 EKX32393.1 - 0.012 15.5 10.4 0.89 9.4 10.4 2.1 1 1 0 1 1 1 0 MspA Toluene_X PF03349.16 EKX32393.1 - 0.015 13.9 2.4 1.7 7.1 0.6 2.3 1 1 1 2 2 2 0 Outer membrane protein transport protein (OMPP1/FadL/TodX) DUF4655 PF15548.6 EKX32393.1 - 0.21 10.5 4.1 0.31 10.0 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4655) Aerolysin PF01117.20 EKX32393.1 - 1.1 8.5 2.1 1.3 8.2 2.1 1.3 1 0 0 1 1 1 0 Aerolysin toxin DUF2715 PF10895.8 EKX32393.1 - 9.2 5.9 23.6 9.4e+03 -3.9 23.6 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF2715) zf-C3HC4_3 PF13920.6 EKX32395.1 - 1.7e-05 24.6 10.5 1.7e-05 24.6 10.5 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX32395.1 - 0.25 11.2 21.5 0.36 10.7 10.0 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) TPR_12 PF13424.6 EKX32396.1 - 2.5e-31 107.8 4.0 8.6e-13 48.4 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX32396.1 - 9.6e-17 60.3 7.2 0.00054 19.7 0.1 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EKX32396.1 - 2.9e-15 55.1 17.3 0.19 12.0 0.0 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 EKX32396.1 - 1.1e-14 53.5 12.4 0.0012 18.6 0.2 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 EKX32396.1 - 7.3e-14 50.7 8.6 0.00052 20.0 0.4 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX32396.1 - 1.5e-11 43.4 11.1 0.0038 17.2 0.1 6.9 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EKX32396.1 - 5.7e-10 39.6 4.7 0.00063 20.2 0.2 5.1 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX32396.1 - 1.5e-09 37.7 0.2 3.6e-09 36.4 0.1 1.6 2 0 0 2 2 2 1 MalT-like TPR region TPR_16 PF13432.6 EKX32396.1 - 2.4e-09 37.7 8.1 0.00021 21.8 0.0 5.0 4 2 1 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX32396.1 - 6.9e-08 32.7 8.3 0.31 12.0 0.0 6.2 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX32396.1 - 3.3e-06 27.4 0.6 0.6 10.9 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 EKX32396.1 - 0.00019 21.7 4.4 0.56 11.0 0.7 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX32396.1 - 0.00033 20.8 4.9 0.081 13.2 1.0 3.9 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF5113 PF17140.4 EKX32396.1 - 0.012 15.4 1.0 2.8 7.8 0.4 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF5113) DUF2225 PF09986.9 EKX32396.1 - 0.012 15.3 0.0 0.044 13.5 0.0 1.9 2 1 0 2 2 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_5 PF12688.7 EKX32396.1 - 0.022 15.0 1.5 0.57 10.4 0.2 3.6 3 1 1 4 4 4 0 Tetratrico peptide repeat HEAT_PBS PF03130.16 EKX32396.1 - 0.4 11.5 4.3 28 5.8 0.1 3.9 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat PPR PF01535.20 EKX32396.1 - 0.43 10.9 2.6 24 5.4 0.4 4.8 5 1 1 6 6 3 0 PPR repeat RPN7 PF10602.9 EKX32396.1 - 0.43 10.3 6.7 3.1 7.5 0.1 3.6 2 1 2 4 4 4 0 26S proteasome subunit RPN7 FKBP_C PF00254.28 EKX32397.1 - 0.037 14.4 0.0 0.085 13.2 0.0 1.6 2 0 0 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase RNA_pol_Rpo13 PF12136.8 EKX32397.1 - 0.067 13.1 3.6 0.11 12.4 3.6 1.3 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain Ank_4 PF13637.6 EKX32398.1 - 1.3e-15 57.5 0.4 0.00019 21.9 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX32398.1 - 2e-15 57.2 0.1 3.1e-15 56.5 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX32398.1 - 2.9e-15 56.1 0.3 2.5e-11 43.6 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX32398.1 - 4e-15 55.5 0.3 2.3e-07 31.0 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EKX32398.1 - 7.4e-12 44.4 0.5 2.3e-05 24.4 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat YpjP PF14005.6 EKX32401.1 - 0.032 14.3 0.3 0.38 10.8 0.3 2.0 1 1 0 1 1 1 0 YpjP-like protein MacB_PCD PF12704.7 EKX32401.1 - 0.7 10.2 5.4 1.7 8.9 5.4 1.7 1 1 0 1 1 1 0 MacB-like periplasmic core domain FAM75 PF14650.6 EKX32401.1 - 3.5 7.1 15.5 4.1 6.9 15.5 1.1 1 0 0 1 1 1 0 FAM75 family COG5 PF10392.9 EKX32402.1 - 0.19 11.9 0.0 0.95 9.6 0.0 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 ABA_WDS PF02496.16 EKX32404.1 - 0.13 12.8 0.1 0.13 12.8 0.1 1.9 2 1 0 2 2 2 0 ABA/WDS induced protein Methyltransf_21 PF05050.12 EKX32405.1 - 4.3e-12 46.4 0.1 6.2e-12 45.9 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase FkbM domain DUF268 PF03269.14 EKX32407.1 - 7.4e-24 84.6 0.0 9.6e-24 84.2 0.0 1.0 1 0 0 1 1 1 1 Caenorhabditis protein of unknown function, DUF268 DUF563 PF04577.14 EKX32410.1 - 3.7e-06 27.2 0.0 5.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Lysis_col PF02402.16 EKX32411.1 - 0.16 11.7 1.2 0.34 10.6 1.2 1.5 1 0 0 1 1 1 0 Lysis protein PolyA_pol_RNAbd PF12627.7 EKX32411.1 - 0.21 11.4 0.1 0.63 9.9 0.0 1.7 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A DUF1664 PF07889.12 EKX32412.1 - 0.016 15.2 0.9 0.54 10.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Vta1 PF04652.16 EKX32412.1 - 0.063 13.2 0.8 1.1 9.2 0.2 2.2 2 0 0 2 2 2 0 Vta1 like Laminin_II PF06009.12 EKX32412.1 - 0.27 11.3 1.9 7.7 6.5 0.1 2.5 3 0 0 3 3 3 0 Laminin Domain II Ground-like PF04155.18 EKX32413.1 - 0.14 12.8 0.2 0.27 11.9 0.2 1.5 1 0 0 1 1 1 0 Ground-like domain Imm75 PF15660.6 EKX32415.1 - 0.12 12.7 3.6 4 7.8 0.4 3.4 3 0 0 3 3 3 0 Putative Immunity protein 75 DUF1987 PF09345.10 EKX32416.1 - 0.064 12.9 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) Cytochrome_CBB3 PF13442.6 EKX32416.1 - 0.5 10.7 5.0 1.3 9.4 4.8 1.8 1 1 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III TNFR_c6 PF00020.18 EKX32417.1 - 9.7e-07 29.1 22.9 1.3e-05 25.5 9.7 5.4 3 1 2 5 5 5 3 TNFR/NGFR cysteine-rich region LRR_4 PF12799.7 EKX32418.1 - 3.8e-06 27.2 12.5 3.9e-05 23.9 3.4 3.7 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX32418.1 - 1.7e-05 24.4 0.7 1.7e-05 24.4 0.7 3.9 3 1 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 EKX32418.1 - 0.51 11.1 9.8 6.2 7.8 0.1 4.6 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 EKX32418.1 - 7.6 6.9 15.0 3.3 8.0 0.6 4.3 4 0 0 4 4 4 0 Leucine Rich repeat Lactonase PF10282.9 EKX32419.1 - 8.1e-05 22.0 0.0 0.017 14.4 0.0 2.2 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller NHL PF01436.21 EKX32419.1 - 8.1e-05 22.5 0.1 0.0023 17.9 0.2 2.6 2 0 0 2 2 2 1 NHL repeat Arylesterase PF01731.20 EKX32419.1 - 0.00012 22.2 0.1 0.96 9.7 0.0 3.1 3 0 0 3 3 3 2 Arylesterase Mrr_cat PF04471.12 EKX32419.1 - 0.21 11.7 0.0 0.73 9.9 0.0 1.8 2 0 0 2 2 2 0 Restriction endonuclease TNFR_c6 PF00020.18 EKX32420.1 - 7.7e-10 39.0 57.5 0.0089 16.4 6.2 6.0 5 0 0 5 5 5 5 TNFR/NGFR cysteine-rich region mit_SMPDase PF14724.6 EKX32421.1 - 0.062 11.3 0.2 0.13 10.2 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial-associated sphingomyelin phosphodiesterase Imm41 PF15592.6 EKX32421.1 - 0.13 12.6 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 41 DUF874 PF05917.11 EKX32421.1 - 0.86 8.6 7.7 1.5 7.8 7.7 1.2 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) DUF1495 PF07381.11 EKX32422.1 - 0.037 13.8 0.1 0.07 13.0 0.1 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain (DUF1495) RelA_SpoT PF04607.17 EKX32423.1 - 9.9e-05 22.6 0.0 0.57 10.5 0.0 2.4 2 0 0 2 2 2 2 Region found in RelA / SpoT proteins TFB6 PF17110.5 EKX32423.1 - 0.077 12.7 1.4 1.4 8.7 0.6 2.4 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH Paf1 PF03985.13 EKX32423.1 - 0.93 8.4 6.4 1.5 7.8 6.4 1.2 1 0 0 1 1 1 0 Paf1 DNA_pol_phi PF04931.13 EKX32423.1 - 1.5 6.8 8.3 2.4 6.2 8.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi MAP17 PF15807.5 EKX32423.1 - 5.4 7.3 9.6 4.9 7.4 0.1 2.6 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Glyco_hydro_14 PF01373.17 EKX32424.1 - 2.1e-91 306.9 1.9 2.3e-91 306.7 1.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 Rhomboid PF01694.22 EKX32426.1 - 9e-37 126.4 4.6 1.7e-36 125.5 4.6 1.5 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 EKX32426.1 - 0.031 14.8 2.2 1.9 9.1 0.0 3.1 2 1 1 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) DER1 PF04511.15 EKX32426.1 - 0.039 13.9 0.3 0.067 13.1 0.3 1.4 1 0 0 1 1 1 0 Der1-like family LRR_8 PF13855.6 EKX32427.1 - 0 1223.4 218.9 3.2e-19 68.4 0.4 23.7 3 1 26 29 29 29 29 Leucine rich repeat LRR_4 PF12799.7 EKX32427.1 - 6.9e-174 560.3 111.7 2.4e-08 34.1 0.1 25.6 12 3 13 29 29 29 28 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX32427.1 - 2e-111 367.3 0.0 9.8e-14 51.4 0.0 10.3 2 1 7 10 10 10 10 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EKX32427.1 - 7.7e-63 199.3 71.5 1.7 9.5 0.1 44.3 46 1 0 46 46 46 4 Leucine Rich Repeat LRR_9 PF14580.6 EKX32427.1 - 3.6e-58 195.9 23.2 0.00025 20.6 0.0 15.2 2 2 13 15 15 15 15 Leucine-rich repeat DUF5598 PF18127.1 EKX32427.1 - 8.8e-10 38.9 3.3 81 3.7 0.0 12.2 3 3 11 18 18 18 0 Domain of unknown function (DUF5598) DUF2610 PF11020.8 EKX32427.1 - 1.1e-07 31.6 0.0 68 3.4 0.0 11.1 4 2 9 15 15 15 0 Domain of unknown function (DUF2610) GST_C_6 PF17171.4 EKX32427.1 - 0.00078 19.2 14.2 17 5.3 0.0 10.4 9 3 3 12 12 12 1 Glutathione S-transferase, C-terminal domain LRR_6 PF13516.6 EKX32427.1 - 0.0024 17.8 134.0 2.9 8.2 0.1 33.7 39 0 0 39 39 39 2 Leucine Rich repeat UNC-50 PF05216.13 EKX32428.1 - 1.5e-51 175.1 3.8 1.7e-51 175.0 3.8 1.0 1 0 0 1 1 1 1 UNC-50 family Peptidase_U4 PF03419.13 EKX32428.1 - 0.016 14.5 0.9 0.023 14.0 0.9 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Phage_holin_3_6 PF07332.11 EKX32428.1 - 0.17 11.9 5.5 0.25 11.4 5.5 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Glyco_tranf_2_4 PF13704.6 EKX32430.1 - 3.9e-07 30.5 0.0 7.6e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glycos_transf_2 PF00535.26 EKX32430.1 - 0.00026 20.8 0.0 0.00051 19.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Ank_2 PF12796.7 EKX32432.1 - 5.8e-12 46.0 0.2 2.5e-11 44.0 0.2 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX32432.1 - 2.1e-11 43.7 0.9 3.2e-05 24.2 0.0 2.9 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EKX32432.1 - 4.4e-11 43.1 0.2 9.9e-06 26.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX32432.1 - 1.7e-08 34.6 0.5 5.6e-08 32.9 0.2 2.0 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX32432.1 - 4.6e-08 32.7 0.1 0.048 14.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Amidase02_C PF12123.8 EKX32433.1 - 0.044 13.5 0.1 0.39 10.4 0.0 2.1 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase Mitofilin PF09731.9 EKX32433.1 - 0.15 10.8 19.4 0.19 10.5 19.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Presenilin PF01080.17 EKX32433.1 - 1.1 7.9 10.8 1.3 7.7 10.8 1.1 1 0 0 1 1 1 0 Presenilin PP_kinase_N PF13089.6 EKX32433.1 - 1.7 9.0 15.7 0.17 12.2 8.2 2.6 1 1 1 2 2 2 0 Polyphosphate kinase N-terminal domain Ndc1_Nup PF09531.10 EKX32433.1 - 1.9 7.1 5.1 2.2 6.9 5.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AAA_11 PF13086.6 EKX32433.1 - 2.6 7.8 16.5 3.3 7.4 16.5 1.1 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 EKX32433.1 - 3.7 6.8 19.2 1.4 8.2 6.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Ank_2 PF12796.7 EKX32436.1 - 1.7e-15 57.4 0.2 0.0045 17.5 0.1 4.8 5 0 0 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX32436.1 - 3.9e-15 54.4 0.0 0.011 16.2 0.1 5.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EKX32436.1 - 2.5e-13 50.2 0.1 0.0021 18.6 0.1 4.7 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX32436.1 - 4.6e-11 42.7 0.0 0.023 15.1 0.1 4.9 4 0 0 4 4 4 4 Ankyrin repeat Ion_trans PF00520.31 EKX32436.1 - 6.4e-09 35.4 10.7 1.1e-08 34.7 10.7 1.2 1 0 0 1 1 1 1 Ion transport protein Ank_5 PF13857.6 EKX32436.1 - 8.4e-05 22.8 0.1 2.6 8.4 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Cadherin_C_2 PF16492.5 EKX32436.1 - 0.16 12.7 1.8 2.1 9.1 0.2 2.9 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Phage_Gp23 PF10669.9 EKX32436.1 - 0.67 10.3 12.8 15 5.9 0.4 3.8 3 0 0 3 3 3 0 Protein gp23 (Bacteriophage A118) Asp PF00026.23 EKX32437.1 - 2.6e-14 53.4 0.0 1.9e-09 37.4 0.0 2.9 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EKX32437.1 - 0.021 15.1 0.1 1.4 9.1 0.0 2.9 3 0 0 3 3 3 0 Xylanase inhibitor N-terminal Ank_2 PF12796.7 EKX32438.1 - 3.9e-15 56.2 1.1 0.00059 20.4 0.4 4.8 4 1 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX32438.1 - 4.9e-15 54.1 0.0 0.0077 16.7 0.1 5.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EKX32438.1 - 4.5e-13 49.4 0.1 0.0014 19.1 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX32438.1 - 4e-11 42.8 0.0 0.012 16.0 0.2 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ion_trans PF00520.31 EKX32438.1 - 1.3e-08 34.3 13.8 2.3e-08 33.6 13.8 1.2 1 0 0 1 1 1 1 Ion transport protein Ank_5 PF13857.6 EKX32438.1 - 0.00011 22.5 0.1 2.1 8.8 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Nop14 PF04147.12 EKX32438.1 - 0.66 8.1 40.1 0.0069 14.7 29.9 2.2 2 0 0 2 2 2 0 Nop14-like family GAGA_bind PF06217.12 EKX32438.1 - 3 8.1 28.5 0.14 12.4 20.7 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family CLN3 PF02487.17 EKX32438.1 - 4.7 6.2 14.3 14 4.6 14.3 2.0 1 0 0 1 1 1 0 CLN3 protein DUF4231 PF14015.6 EKX32438.1 - 9.2 6.8 7.8 19 5.8 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Zip PF02535.22 EKX32439.1 - 2.4e-26 92.8 23.4 9.5e-25 87.5 23.4 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter CbtA PF09490.10 EKX32439.1 - 5.1 6.8 12.9 0.096 12.4 1.2 3.1 3 1 1 4 4 4 0 Probable cobalt transporter subunit (CbtA) Sulfotransfer_1 PF00685.27 EKX32440.1 - 6.3e-27 94.7 0.0 1.2e-26 93.8 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EKX32440.1 - 1.1e-07 32.5 0.0 8.6e-06 26.3 0.0 2.7 2 1 0 2 2 2 1 Sulfotransferase family Phage_Gp23 PF10669.9 EKX32442.1 - 0.16 12.3 0.1 0.16 12.3 0.1 2.1 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Pkinase PF00069.25 EKX32443.1 - 1.1e-58 198.7 0.0 1.4e-58 198.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX32443.1 - 7.6e-37 127.0 0.0 1.1e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EKX32443.1 - 0.00057 18.9 0.0 0.00075 18.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EKX32443.1 - 0.00061 18.7 0.0 0.00085 18.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EKX32443.1 - 0.0045 16.1 0.0 0.0068 15.5 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 EKX32443.1 - 0.0087 16.0 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EKX32443.1 - 0.029 14.0 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 EKX32443.1 - 0.067 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EKX32443.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ion_trans PF00520.31 EKX32444.1 - 1.5e-05 24.4 5.1 1.6e-05 24.3 5.1 1.0 1 0 0 1 1 1 1 Ion transport protein DUF445 PF04286.12 EKX32445.1 - 0.17 11.7 0.3 0.45 10.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF445) PHD PF00628.29 EKX32446.1 - 2.4e-06 27.3 13.2 2.4e-06 27.3 13.2 3.1 2 1 0 2 2 2 1 PHD-finger AP2 PF00847.20 EKX32446.1 - 0.085 13.1 1.4 6.1 7.2 0.2 3.0 3 0 0 3 3 3 0 AP2 domain RPA_interact_C PF14768.6 EKX32446.1 - 3.6 8.2 11.2 3.7 8.2 0.8 3.2 3 0 0 3 3 3 0 Replication protein A interacting C-terminal Prok-RING_1 PF14446.6 EKX32446.1 - 6.9 6.7 11.8 2.4 8.2 4.8 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 MFS_1 PF07690.16 EKX32447.1 - 1.4e-27 96.5 45.1 1.3e-19 70.3 22.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EKX32447.1 - 3.9e-10 38.9 25.1 1.7e-09 36.8 25.1 1.8 1 1 0 1 1 1 1 MFS/sugar transport protein DUF5337 PF17272.2 EKX32447.1 - 0.17 11.8 1.8 0.5 10.2 0.2 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5337) MFS_3 PF05977.13 EKX32447.1 - 0.22 9.9 9.0 0.0097 14.3 2.1 2.0 2 0 0 2 2 2 0 Transmembrane secretion effector CybS PF05328.12 EKX32447.1 - 0.22 11.2 5.7 0.095 12.4 1.0 2.3 2 0 0 2 2 2 0 CybS, succinate dehydrogenase cytochrome B small subunit HisKA_4TM PF16926.5 EKX32447.1 - 0.65 9.6 4.3 0.54 9.8 1.9 2.1 2 0 0 2 2 2 0 Archaeal 4TM region of histidine kinase Ephrin_rec_like PF07699.13 EKX32448.1 - 3.7e-29 100.2 81.1 3.3e-09 36.4 8.1 8.1 2 2 7 9 9 9 8 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX32448.1 - 3e-08 33.9 56.1 0.062 13.7 0.9 10.0 4 3 7 11 11 11 10 TNFR/NGFR cysteine-rich region VSP PF03302.13 EKX32448.1 - 0.0087 15.0 16.9 0.0087 15.0 16.9 3.8 1 1 3 4 4 4 3 Giardia variant-specific surface protein Carb_anhydrase PF00194.21 EKX32450.1 - 4e-14 52.8 0.1 1.1e-13 51.3 0.1 1.7 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase PDZ_6 PF17820.1 EKX32450.1 - 5.8e-05 22.9 0.0 0.00016 21.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX32450.1 - 0.0011 19.3 0.0 0.0023 18.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX32450.1 - 0.0019 18.5 0.3 0.007 16.7 0.0 2.0 2 0 0 2 2 2 1 PDZ domain NUDIX PF00293.28 EKX32452.1 - 0.19 11.8 4.5 0.081 13.0 0.9 2.2 2 1 0 2 2 2 0 NUDIX domain KfrA_N PF11740.8 EKX32452.1 - 0.23 12.2 1.4 7.7 7.2 0.3 2.7 2 1 1 3 3 3 0 Plasmid replication region DNA-binding N-term PDZ_2 PF13180.6 EKX32453.1 - 7e-10 39.1 0.7 7e-10 39.1 0.7 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EKX32453.1 - 1.2e-09 37.9 1.0 1.9e-09 37.2 1.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX32453.1 - 3.1e-06 27.4 2.0 3.1e-06 27.4 2.0 1.7 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 EKX32453.1 - 0.0025 17.8 0.2 0.0055 16.6 0.2 1.6 1 0 0 1 1 1 1 Tricorn protease PDZ domain NINJA_B PF16136.5 EKX32453.1 - 0.016 15.6 1.7 0.027 14.8 1.7 1.4 1 0 0 1 1 1 0 Putative nuclear localisation signal DUF728 PF05304.12 EKX32453.1 - 0.085 12.7 1.7 0.22 11.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF728) RelA_SpoT PF04607.17 EKX32453.1 - 0.18 12.1 2.7 1.1 9.5 0.2 2.3 1 1 1 2 2 2 0 Region found in RelA / SpoT proteins DUF4508 PF14969.6 EKX32456.1 - 0.0043 17.3 1.5 3.5 7.9 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4508) zf-C4 PF00105.18 EKX32456.1 - 0.01 16.2 2.8 4.6 7.8 0.2 2.7 2 0 0 2 2 2 0 Zinc finger, C4 type (two domains) FliG_C PF01706.16 EKX32456.1 - 0.028 14.6 1.4 8.5 6.6 0.1 2.8 2 0 0 2 2 2 0 FliG C-terminal domain SapA PF02199.15 EKX32456.1 - 0.064 13.6 1.4 13 6.1 0.1 2.4 2 0 0 2 2 2 0 Saposin A-type domain Suppressor_APC PF11414.8 EKX32456.1 - 0.064 13.3 2.7 10 6.3 0.2 2.8 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein RelB PF04221.12 EKX32456.1 - 0.066 13.2 0.1 4.3 7.4 0.0 3.6 3 0 0 3 3 3 0 RelB antitoxin ATP-synt_F PF01990.17 EKX32456.1 - 0.068 13.5 0.1 28 5.1 0.0 2.8 2 0 0 2 2 2 0 ATP synthase (F/14-kDa) subunit Peptidase_M9_N PF08453.10 EKX32456.1 - 0.23 11.2 3.5 17 5.0 0.1 3.4 4 0 0 4 4 4 0 Peptidase family M9 N-terminal CAP-ZIP_m PF15255.6 EKX32456.1 - 4.6 7.5 7.9 34 4.7 0.2 3.8 4 0 0 4 4 4 0 WASH complex subunit CAP-Z interacting, central region NUP50 PF08911.11 EKX32459.1 - 0.1 13.3 4.7 0.11 13.2 4.3 1.5 1 1 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) DUF4200 PF13863.6 EKX32460.1 - 0.037 14.4 1.6 0.055 13.9 1.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) HAUS-augmin3 PF14932.6 EKX32460.1 - 0.053 13.1 0.0 0.057 13.0 0.0 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF5534 PF17686.1 EKX32460.1 - 0.2 11.9 0.6 4.1 7.6 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5534) PDZ PF00595.24 EKX32461.1 - 6.5e-15 55.2 2.7 1.7e-08 34.7 0.1 3.1 2 1 1 3 3 3 2 PDZ domain PDZ_2 PF13180.6 EKX32461.1 - 1.8e-10 41.0 1.6 0.0036 17.6 0.0 3.5 1 1 2 3 3 3 3 PDZ domain PDZ_6 PF17820.1 EKX32461.1 - 6.8e-10 38.7 2.8 6.2e-06 26.0 0.2 3.7 3 0 0 3 3 3 2 PDZ domain Zip PF02535.22 EKX32461.1 - 0.19 10.9 1.3 0.42 9.8 1.3 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Spt20 PF12090.8 EKX32461.1 - 0.3 10.6 26.9 0.77 9.3 26.9 1.6 1 0 0 1 1 1 0 Spt20 family Asparaginase_2 PF01112.18 EKX32461.1 - 0.44 9.5 3.2 1.1 8.2 3.2 1.6 1 0 0 1 1 1 0 Asparaginase DUF2859 PF11072.8 EKX32461.1 - 0.49 10.1 0.0 0.49 10.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2859) RPA43_OB PF17875.1 EKX32461.1 - 2.7 8.6 10.9 0.14 12.7 3.9 2.3 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Pex14_N PF04695.13 EKX32461.1 - 2.9 8.5 15.2 0.24 12.0 10.0 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EPL1 PF10513.9 EKX32461.1 - 3.2 8.1 13.9 0.2 12.0 4.3 2.5 2 0 0 2 2 2 0 Enhancer of polycomb-like FAM76 PF16046.5 EKX32461.1 - 4.6 6.5 22.7 0.018 14.4 3.7 3.6 3 1 0 3 3 3 0 FAM76 protein Baculo_PP31 PF05311.11 EKX32461.1 - 4.8 6.6 8.7 12 5.3 8.7 1.6 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) CCDC53 PF10152.9 EKX32461.1 - 4.9 7.6 13.2 0.26 11.7 3.6 3.0 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex GET2 PF08690.10 EKX32461.1 - 9.2 5.8 14.7 2 8.0 10.6 2.0 2 0 0 2 2 2 0 GET complex subunit GET2 Ribosomal_L2_C PF03947.18 EKX32464.1 - 0.05 13.8 0.1 15 5.8 0.0 2.3 2 0 0 2 2 2 0 Ribosomal Proteins L2, C-terminal domain Cullin PF00888.22 EKX32465.1 - 3e-107 359.8 0.0 3.8e-107 359.4 0.0 1.0 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EKX32465.1 - 1e-09 38.3 0.2 2.1e-09 37.3 0.2 1.5 1 0 0 1 1 1 1 Cullin protein neddylation domain MGDG_synth PF06925.11 EKX32465.1 - 0.017 15.2 0.3 1.1 9.3 0.0 3.0 3 1 1 4 4 4 0 Monogalactosyldiacylglycerol (MGDG) synthase Transcrip_reg PF01709.20 EKX32466.1 - 6.9e-32 110.8 3.1 9.6e-32 110.3 3.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator UCR_14kD PF02271.16 EKX32468.1 - 6.5e-21 74.2 0.4 7.6e-21 74.0 0.4 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit BshC PF10079.9 EKX32468.1 - 0.0062 15.3 0.0 0.0068 15.2 0.0 1.0 1 0 0 1 1 1 1 Bacillithiol biosynthesis BshC DUF639 PF04842.12 EKX32469.1 - 1.1e-11 44.6 0.1 3.5e-05 23.3 0.1 2.2 2 0 0 2 2 2 2 Plant protein of unknown function (DUF639) GRAM PF02893.20 EKX32469.1 - 0.03 14.2 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 GRAM domain DUF3600 PF12207.8 EKX32469.1 - 0.086 12.8 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3600) DUF1279 PF06916.13 EKX32471.1 - 1.3e-09 38.4 0.0 2.5e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) TRAP-gamma PF07074.12 EKX32472.1 - 2.9e-16 59.5 0.8 3.7e-16 59.1 0.8 1.1 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF2663 PF10864.8 EKX32472.1 - 0.036 14.5 0.2 1.4 9.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) DUF2721 PF11026.8 EKX32472.1 - 0.12 12.3 5.1 0.038 13.9 1.6 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF2721) 7TM_GPCR_Srw PF10324.9 EKX32473.1 - 0.098 11.9 0.1 0.12 11.6 0.1 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw 4HB_MCP_1 PF12729.7 EKX32473.1 - 0.26 10.8 0.5 0.36 10.4 0.5 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction 4HBT PF03061.22 EKX32474.1 - 1.1e-07 32.1 0.0 1.6e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily UPF0139 PF03669.13 EKX32475.1 - 5.8e-29 99.8 0.0 6.2e-29 99.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) DUF3989 PF13150.6 EKX32475.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3989) IPTL-CTERM PF18203.1 EKX32475.1 - 1.4 8.9 8.2 10 6.2 7.0 2.3 2 0 0 2 2 2 0 IPTL-CTERM motif BAH PF01426.18 EKX32476.1 - 2.6e-28 98.3 1.7 9.9e-14 51.2 0.0 2.6 3 0 0 3 3 3 2 BAH domain TPR_1 PF00515.28 EKX32479.1 - 9.7e-11 41.0 2.2 0.002 17.9 0.1 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX32479.1 - 2.3e-08 33.5 3.3 0.013 15.6 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX32479.1 - 4.8e-06 26.8 4.9 0.0019 18.5 2.4 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX32479.1 - 1.5e-05 24.8 1.8 0.031 14.5 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX32479.1 - 4e-05 23.8 3.0 9.8e-05 22.5 1.2 1.9 1 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 EKX32479.1 - 5.5e-05 23.2 2.2 0.0058 16.7 0.0 3.0 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 EKX32479.1 - 5.8e-05 23.5 0.2 0.0017 18.8 0.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX32479.1 - 0.0063 16.6 0.2 0.033 14.3 0.0 2.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX32479.1 - 0.012 15.2 1.3 0.6 9.8 0.0 2.7 2 1 1 3 3 3 0 TPR repeat BTAD PF03704.17 EKX32479.1 - 0.045 14.2 0.9 0.094 13.2 0.8 1.7 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_14 PF13428.6 EKX32479.1 - 0.047 14.5 0.6 2.9 9.0 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EKX32479.1 - 0.078 13.6 0.1 3.5 8.4 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX32479.1 - 0.21 11.5 5.5 8.3 6.4 0.3 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 EKX32479.1 - 0.57 10.3 4.3 1.7 8.8 0.8 2.7 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain EF-hand_7 PF13499.6 EKX32482.1 - 1.1e-28 99.5 6.9 1.5e-14 54.2 0.3 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX32482.1 - 5.7e-25 85.0 14.7 1.2e-07 30.8 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EKX32482.1 - 6.2e-23 78.7 12.1 5.4e-09 35.3 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EKX32482.1 - 2.8e-18 65.5 11.3 5.4e-10 39.0 0.4 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EKX32482.1 - 3.5e-13 48.4 17.2 0.00013 21.3 0.6 4.5 4 1 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EKX32482.1 - 2.1e-12 47.1 0.2 4.7e-07 30.0 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EKX32482.1 - 2.2e-06 27.5 4.4 0.0058 16.6 0.2 2.6 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EKX32482.1 - 7.3e-05 23.1 1.0 0.006 16.9 0.2 2.4 1 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 EKX32482.1 - 0.00077 19.3 6.7 0.0011 18.7 0.8 3.0 2 1 1 3 3 3 1 EF hand EF-hand_14 PF17959.1 EKX32482.1 - 0.0012 19.2 0.1 0.44 10.9 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.13 EKX32482.1 - 0.02 14.9 0.1 0.7 10.0 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) PSD5 PF07637.11 EKX32482.1 - 0.023 15.0 0.1 0.56 10.6 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1595) Toprim_2 PF13155.6 EKX32482.1 - 0.067 13.6 0.6 2.7 8.5 0.0 2.4 2 1 0 2 2 2 0 Toprim-like Caleosin PF05042.13 EKX32482.1 - 0.069 13.1 0.2 4.5 7.2 0.1 2.3 1 1 1 2 2 2 0 Caleosin related protein Cadherin_C PF01049.17 EKX32482.1 - 3 8.2 5.7 4 7.8 0.1 2.1 1 1 1 2 2 2 0 Cadherin cytoplasmic region Anoctamin PF04547.12 EKX32483.1 - 0.007 15.3 1.7 0.007 15.3 1.7 2.3 2 1 0 2 2 2 1 Calcium-activated chloride channel Tetraspanin PF00335.20 EKX32483.1 - 0.3 10.7 37.0 0.31 10.7 6.6 3.5 1 1 1 3 3 3 0 Tetraspanin family DUF1129 PF06570.11 EKX32483.1 - 1.3 8.4 17.2 0.072 12.6 9.9 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1129) Phycoerythr_ab PF02972.14 EKX32484.1 - 9.4e-19 67.0 0.9 1.4e-18 66.4 0.0 1.7 2 0 0 2 2 2 1 Phycoerythrin, alpha/beta chain TAT_signal PF10518.9 EKX32484.1 - 0.0067 16.2 9.2 0.0067 16.2 9.2 2.8 2 2 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence UPAR_LY6 PF00021.21 EKX32484.1 - 0.051 14.3 0.3 0.084 13.6 0.3 1.3 1 0 0 1 1 1 0 u-PAR/Ly-6 domain MOZART2 PF12926.7 EKX32484.1 - 0.064 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated UAA PF08449.11 EKX32485.1 - 7.6e-59 199.4 22.0 1e-58 198.9 22.0 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EKX32485.1 - 2.6e-05 24.4 13.3 2.6e-05 24.4 13.3 2.9 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EKX32485.1 - 0.0027 17.1 15.0 0.0041 16.5 15.0 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family DUF5367 PF17329.2 EKX32485.1 - 0.15 12.2 9.1 0.064 13.4 3.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5367) DUF3671 PF12420.8 EKX32485.1 - 0.47 10.5 7.3 0.47 10.5 0.7 2.7 3 0 0 3 3 3 0 Protein of unknown function DNA_alkylation PF08713.11 EKX32486.1 - 9.2e-17 61.5 0.1 1.1e-16 61.2 0.1 1.1 1 0 0 1 1 1 1 DNA alkylation repair enzyme DNAPolymera_Pol PF11590.8 EKX32486.1 - 0.07 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase catalytic subunit Pol PAT1 PF09770.9 EKX32488.1 - 0.072 11.4 17.0 0.096 10.9 17.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2151 PF10221.9 EKX32488.1 - 2.4 6.6 14.6 3.3 6.2 14.6 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Tim54 PF11711.8 EKX32488.1 - 6.5 5.4 14.9 9.4 4.9 14.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Borrelia_P83 PF05262.11 EKX32488.1 - 8.7 4.7 15.9 12 4.3 15.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CPSF100_C PF13299.6 EKX32489.1 - 0.24 11.6 4.2 0.26 11.5 2.7 1.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF1325 PF07039.11 EKX32490.1 - 0.006 16.7 0.2 0.018 15.1 0.2 1.8 1 1 0 1 1 1 1 SGF29 tudor-like domain DUF3509 PF12021.8 EKX32490.1 - 0.018 14.8 0.0 3.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3509) LysM PF01476.20 EKX32490.1 - 0.039 14.0 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 LysM domain Phycoerythr_ab PF02972.14 EKX32491.1 - 4.9e-24 83.9 0.1 9.8e-24 82.9 0.1 1.5 1 0 0 1 1 1 1 Phycoerythrin, alpha/beta chain HTH_Tnp_Tc5 PF03221.16 EKX32492.1 - 0.00015 21.7 0.2 0.00033 20.6 0.2 1.7 1 1 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 EKX32492.1 - 0.00065 19.3 0.8 0.00065 19.3 0.8 1.9 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 EKX32492.1 - 0.0014 18.3 1.2 0.0028 17.4 1.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.22 EKX32492.1 - 0.019 15.0 0.4 0.055 13.5 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix HTH_23 PF13384.6 EKX32492.1 - 0.056 13.3 0.2 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Spb1_C PF07780.12 EKX32492.1 - 0.076 12.6 0.8 0.1 12.2 0.8 1.2 1 0 0 1 1 1 0 Spb1 C-terminal domain DUF1281_C PF18406.1 EKX32493.1 - 0.03 14.0 0.6 0.075 12.7 0.6 1.7 1 1 0 1 1 1 0 Ferredoxin-like domain in Api92-like protein Kelch_4 PF13418.6 EKX32493.1 - 0.031 14.3 0.5 0.52 10.4 0.0 2.4 2 0 0 2 2 2 0 Galactose oxidase, central domain DUF829 PF05705.14 EKX32494.1 - 1.4e-31 110.3 0.0 2.3e-31 109.5 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DLH PF01738.18 EKX32494.1 - 0.067 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family Enkurin PF13864.6 EKX32495.1 - 6.8e-19 68.1 0.4 6.8e-19 68.1 0.4 2.4 2 1 0 2 2 2 1 Calmodulin-binding zf-CCCH_4 PF18044.1 EKX32496.1 - 5.3e-12 45.2 13.4 2.5e-06 27.2 2.2 2.7 2 1 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 EKX32496.1 - 3.3e-09 36.4 14.1 6.2e-05 22.8 3.4 2.8 2 2 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EKX32496.1 - 4.1e-08 33.0 15.5 0.00018 21.5 0.9 3.5 3 1 0 3 3 3 2 Zinc finger domain zf-CCCH_2 PF14608.6 EKX32496.1 - 0.001 19.4 14.9 0.036 14.6 2.7 2.6 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 EKX32496.1 - 0.0029 18.3 3.4 0.72 10.6 0.2 2.3 1 1 1 2 2 2 2 Torus domain CLIP PF12032.8 EKX32496.1 - 0.021 15.1 2.6 1.6 9.0 0.3 2.4 2 0 0 2 2 2 0 Regulatory CLIP domain of proteinases Atrophin-1 PF03154.15 EKX32496.1 - 1.9 6.7 4.5 1.3 7.3 2.9 1.4 1 1 0 1 1 1 0 Atrophin-1 family zf-CCHH PF10283.9 EKX32496.1 - 2.3 8.3 4.4 23 5.1 0.3 2.6 2 0 0 2 2 2 0 PBZ domain Gamma-thionin PF00304.20 EKX32496.1 - 5.9 7.2 15.0 3.4 8.0 1.4 2.8 3 0 0 3 3 3 0 Gamma-thionin family TPR_1 PF00515.28 EKX32497.1 - 2.2e-05 24.1 0.1 0.0039 16.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX32497.1 - 0.00021 21.2 4.9 0.0085 16.1 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX32497.1 - 0.00021 21.3 0.1 0.056 13.7 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX32497.1 - 0.00045 19.8 0.4 1.3 8.7 0.0 2.8 3 0 0 3 3 3 2 TPR repeat TPR_17 PF13431.6 EKX32497.1 - 0.0016 18.7 0.1 0.94 10.0 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX32497.1 - 0.0029 18.3 1.7 6.4 7.9 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX32497.1 - 0.01 15.8 0.0 0.05 13.6 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX32497.1 - 0.056 13.9 0.7 1.8 9.2 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Sybindin PF04099.12 EKX32498.1 - 3.1e-43 147.1 0.0 3.4e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EKX32498.1 - 1.4e-05 25.3 0.0 2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region EptA_B_N PF08019.12 EKX32499.1 - 0.65 9.9 4.0 1.6 8.6 0.0 3.0 2 1 1 3 3 3 0 Phosphoethanolamine transferase EptA/EptB Arm PF00514.23 EKX32502.1 - 3.5e-08 33.2 4.7 0.85 9.8 0.0 5.6 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat UNC45-central PF11701.8 EKX32502.1 - 0.0051 16.8 0.2 0.33 10.9 0.0 2.7 1 1 1 2 2 2 1 Myosin-binding striated muscle assembly central DUF3361 PF11841.8 EKX32502.1 - 0.034 14.1 0.0 0.22 11.5 0.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3361) Wap1 PF16997.5 EKX32502.1 - 0.21 10.7 0.2 0.34 10.0 0.2 1.2 1 0 0 1 1 1 0 Wap1 domain ATG16 PF08614.11 EKX32503.1 - 0.39 10.9 43.7 0.041 14.1 9.6 3.2 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Laminin_I PF06008.14 EKX32503.1 - 0.39 10.4 30.4 1.3 8.6 1.6 3.4 3 1 0 3 3 3 0 Laminin Domain I Rootletin PF15035.6 EKX32503.1 - 4.2 7.4 31.0 0.62 10.0 14.5 2.8 1 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF3450 PF11932.8 EKX32503.1 - 7.1 5.9 38.6 0.046 13.0 6.6 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Amino_oxidase PF01593.24 EKX32504.1 - 4.8e-19 69.0 0.0 9.8e-10 38.3 0.0 2.4 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EKX32504.1 - 1.4e-15 57.3 0.2 3.2e-15 56.1 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EKX32504.1 - 1.2e-10 41.0 1.4 1.4e-06 27.6 1.2 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EKX32504.1 - 2.1e-09 37.4 2.1 1.1e-05 25.2 0.0 2.9 2 1 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EKX32504.1 - 8.9e-09 34.5 0.9 0.00024 20.0 0.6 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 EKX32504.1 - 2.3e-07 30.4 0.2 5.3e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EKX32504.1 - 1.1e-06 28.1 0.3 1.9e-06 27.3 0.3 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 EKX32504.1 - 1.2e-06 28.0 0.3 2e-06 27.3 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EKX32504.1 - 4.6e-06 27.1 4.6 0.0014 19.2 0.5 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EKX32504.1 - 3.8e-05 22.9 0.3 0.005 16.0 0.1 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein GDI PF00996.18 EKX32504.1 - 5.8e-05 21.8 0.1 0.16 10.4 0.1 2.2 2 0 0 2 2 2 2 GDP dissociation inhibitor GIDA PF01134.22 EKX32504.1 - 0.00013 21.1 2.2 0.014 14.5 1.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 EKX32504.1 - 0.0017 17.8 0.7 0.0041 16.5 0.4 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EKX32504.1 - 0.0041 16.4 0.2 0.011 15.0 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EKX32504.1 - 0.0061 15.9 0.0 0.0094 15.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain MCRA PF06100.11 EKX32504.1 - 0.032 13.0 0.1 0.17 10.7 0.1 2.0 2 0 0 2 2 2 0 MCRA family 3HCDH_N PF02737.18 EKX32504.1 - 0.11 12.3 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Myb_DNA-binding PF00249.31 EKX32507.1 - 1.8e-20 72.8 9.4 1e-18 67.2 2.9 2.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX32507.1 - 9.8e-20 70.6 1.6 1.3e-19 70.2 1.6 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain SLIDE PF09111.10 EKX32507.1 - 0.0015 18.5 0.2 0.0098 15.9 0.1 1.9 1 1 1 2 2 2 1 SLIDE Myb_DNA-bind_7 PF15963.5 EKX32507.1 - 0.013 15.4 0.2 0.016 15.1 0.2 1.2 1 0 0 1 1 1 0 Myb DNA-binding like Exo70 PF03081.15 EKX32507.1 - 0.015 14.3 0.1 0.015 14.3 0.1 1.1 1 0 0 1 1 1 0 Exo70 exocyst complex subunit Rap1_C PF11626.8 EKX32507.1 - 0.026 14.6 0.4 0.23 11.6 0.1 2.0 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 EKX32507.1 - 0.069 13.3 1.5 0.7 10.1 0.5 2.4 1 1 1 2 2 2 0 Rap1 Myb domain 53-BP1_Tudor PF09038.10 EKX32507.1 - 0.079 12.9 0.2 0.092 12.7 0.2 1.1 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor PDZ_2 PF13180.6 EKX32508.1 - 2.7e-11 43.6 0.3 7.1e-11 42.3 0.3 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX32508.1 - 2.5e-09 36.8 1.2 5.5e-09 35.7 1.2 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX32508.1 - 3.9e-08 33.5 0.9 8.1e-08 32.5 0.9 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX32508.1 - 0.0003 20.7 0.2 0.0007 19.5 0.2 1.6 1 0 0 1 1 1 1 Tricorn protease PDZ domain MYO10_CC PF16735.5 EKX32508.1 - 0.0066 16.5 8.0 0.0066 16.5 8.0 4.9 3 2 1 4 4 4 1 Unconventional myosin-X coiled coil domain DUF5394 PF17372.2 EKX32508.1 - 1.3 8.5 15.3 0.95 9.0 13.8 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5394) LMBR1 PF04791.16 EKX32508.1 - 5.3 5.8 11.2 6.5 5.5 11.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Syntaxin-6_N PF09177.11 EKX32508.1 - 6.9 7.3 14.2 0.084 13.4 4.2 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal STN1_2 PF09170.10 EKX32509.1 - 0.058 13.6 1.5 0.072 13.3 1.5 1.2 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 DUF4317 PF14199.6 EKX32509.1 - 0.1 11.7 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4317) LMBR1 PF04791.16 EKX32509.1 - 0.18 10.7 5.7 0.22 10.4 5.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TerB_C PF15615.6 EKX32509.1 - 0.94 9.8 3.1 0.4 11.0 0.9 1.5 2 0 0 2 2 2 0 TerB-C domain Not3 PF04065.15 EKX32509.1 - 3.1 7.2 9.8 1.2 8.6 1.6 2.0 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component DnaJ PF00226.31 EKX32510.1 - 5.6e-27 93.6 1.1 7.8e-27 93.2 0.1 1.8 2 0 0 2 2 2 1 DnaJ domain DUF1759 PF03564.15 EKX32511.1 - 0.0072 16.3 0.2 0.024 14.6 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) ATG16 PF08614.11 EKX32511.1 - 0.018 15.3 4.2 0.018 15.3 4.2 4.3 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) YtzH PF14165.6 EKX32511.1 - 0.027 14.9 0.5 2.3 8.7 0.0 2.7 2 0 0 2 2 2 0 YtzH-like protein TPR_MLP1_2 PF07926.12 EKX32511.1 - 0.12 12.4 13.0 0.33 11.0 2.8 3.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein SlyX PF04102.12 EKX32511.1 - 0.77 10.4 6.6 2.5 8.8 0.3 3.5 3 0 0 3 3 3 0 SlyX SSP160 PF06933.11 EKX32511.1 - 0.89 7.7 14.3 1.3 7.1 14.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 XhlA PF10779.9 EKX32511.1 - 8.1 6.7 6.2 10 6.4 0.4 2.8 2 1 1 3 3 3 0 Haemolysin XhlA MBT PF02820.18 EKX32512.1 - 0.0033 17.7 0.1 0.0077 16.6 0.1 1.5 1 0 0 1 1 1 1 mbt repeat Tudor-knot PF11717.8 EKX32512.1 - 0.0057 16.5 0.4 0.019 14.9 0.1 2.1 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain SNF2_N PF00176.23 EKX32516.1 - 2.7e-66 223.7 0.0 3.9e-66 223.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX32516.1 - 4.1e-16 59.3 0.0 8.5e-15 55.1 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX32516.1 - 2.8e-07 30.7 0.0 1.1e-06 28.8 0.0 2.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EKX32516.1 - 3.5e-05 23.1 0.1 0.00013 21.3 0.1 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 EKX32516.1 - 0.001 18.8 0.0 0.0041 16.8 0.0 2.0 1 1 0 1 1 1 1 SWI2/SNF2 ATPase DEAD PF00270.29 EKX32516.1 - 0.0014 18.4 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD PF00270.29 EKX32518.1 - 9.8e-11 41.7 0.2 1.3e-10 41.3 0.2 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EKX32518.1 - 3.8e-05 23.8 0.1 5.4e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EKX32518.1 - 9.7e-05 22.7 0.2 0.00017 21.9 0.2 1.4 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EKX32518.1 - 0.00017 21.6 0.1 0.00023 21.2 0.1 1.0 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_11 PF13086.6 EKX32518.1 - 0.00021 21.2 0.2 0.00025 20.9 0.2 1.1 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EKX32518.1 - 0.00023 20.6 0.0 0.00034 20.0 0.0 1.5 1 1 0 1 1 1 1 KaiC AAA_16 PF13191.6 EKX32518.1 - 0.0022 18.4 0.0 0.0038 17.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EKX32518.1 - 0.0037 16.7 0.2 0.032 13.7 0.0 2.0 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 EKX32518.1 - 0.0067 16.4 0.0 0.014 15.4 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 EKX32518.1 - 0.0092 15.7 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EKX32518.1 - 0.018 14.5 0.1 0.073 12.5 0.0 2.0 2 1 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.6 EKX32518.1 - 0.023 14.7 0.1 0.73 9.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EKX32518.1 - 0.023 14.6 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 EKX32518.1 - 0.023 15.2 0.3 0.035 14.6 0.3 1.5 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 EKX32518.1 - 0.027 15.0 0.1 0.093 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EKX32518.1 - 0.029 14.1 0.0 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.14 EKX32518.1 - 0.073 13.1 0.1 0.24 11.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 EKX32518.1 - 0.08 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 EKX32518.1 - 0.081 13.3 0.2 0.65 10.4 0.0 2.5 3 1 0 3 3 3 0 RNA helicase HutP PF09021.11 EKX32518.1 - 0.1 12.9 0.1 0.18 12.2 0.1 1.4 1 0 0 1 1 1 0 HutP Helicase_RecD PF05127.14 EKX32518.1 - 0.12 12.2 0.1 0.19 11.6 0.1 1.5 1 1 0 1 1 1 0 Helicase SLC12 PF03522.15 EKX32520.1 - 0.004 16.2 19.8 0.0042 16.2 19.8 1.0 1 0 0 1 1 1 1 Solute carrier family 12 Apt1 PF10351.9 EKX32520.1 - 0.12 11.2 14.4 0.12 11.2 14.4 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 EKX32520.1 - 0.32 9.7 31.7 0.37 9.5 31.7 1.0 1 0 0 1 1 1 0 Presenilin DUF3807 PF12720.7 EKX32520.1 - 0.65 10.2 39.3 0.89 9.8 39.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Membralin PF09746.9 EKX32520.1 - 0.99 8.4 11.8 1.1 8.2 11.8 1.1 1 0 0 1 1 1 0 Tumour-associated protein PARP PF00644.20 EKX32521.1 - 5.6e-23 81.6 0.0 4.2e-22 78.7 0.0 2.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain DivIC PF04977.15 EKX32521.1 - 3.7 7.4 8.8 9.5 6.1 8.8 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF724 PF05266.14 EKX32521.1 - 5 6.9 9.8 7.7 6.3 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) YlqD PF11068.8 EKX32521.1 - 5.1 7.5 13.9 10 6.5 0.0 2.6 2 0 0 2 2 2 0 YlqD protein Pkinase PF00069.25 EKX32522.1 - 3.1e-36 125.1 0.0 1.1e-35 123.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX32522.1 - 1.3e-21 77.1 0.0 1.6e-21 76.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX32522.1 - 2.3e-08 33.2 0.0 3.1e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EKX32522.1 - 0.00035 20.0 0.5 0.00061 19.2 0.5 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX32522.1 - 0.0032 17.4 0.4 0.0074 16.2 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EKX32522.1 - 0.0086 15.7 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.9 EKX32522.1 - 0.03 13.8 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL TIR_2 PF13676.6 EKX32523.1 - 2e-16 60.6 0.1 9.1e-16 58.5 0.0 2.2 2 0 0 2 2 2 1 TIR domain Roc PF08477.13 EKX32523.1 - 2.4e-15 56.8 0.0 6e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 EKX32523.1 - 1.5e-14 54.3 0.0 3.6e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Ras PF00071.22 EKX32523.1 - 3.3e-07 30.1 0.0 7.4e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Ras family Arf PF00025.21 EKX32523.1 - 1.9e-06 27.4 0.1 5.1e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family TIR PF01582.20 EKX32523.1 - 0.00095 19.0 0.1 0.0022 17.8 0.1 1.7 1 0 0 1 1 1 1 TIR domain Gtr1_RagA PF04670.12 EKX32523.1 - 0.0018 17.7 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EKX32523.1 - 0.013 15.6 0.0 0.045 13.8 0.0 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.20 EKX32523.1 - 0.025 13.7 0.1 0.065 12.4 0.1 1.6 1 1 0 1 1 1 0 G-protein alpha subunit Rotamase PF00639.21 EKX32523.1 - 0.031 15.2 0.2 0.53 11.3 0.2 3.0 2 0 0 2 2 2 0 PPIC-type PPIASE domain SRPRB PF09439.10 EKX32523.1 - 0.045 13.2 0.0 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Acetyltransf_7 PF13508.7 EKX32524.1 - 9.5e-10 38.8 0.0 2.1e-09 37.6 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EKX32524.1 - 6.8e-09 36.0 0.0 9.3e-09 35.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EKX32524.1 - 7.6e-09 35.6 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EKX32524.1 - 5.6e-05 23.0 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein GNAT_acetyltran PF12746.7 EKX32524.1 - 0.017 14.7 0.0 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 GNAT acetyltransferase RRM_1 PF00076.22 EKX32526.1 - 9.8e-11 41.3 0.0 3.7e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pirin_C_2 PF17954.1 EKX32526.1 - 0.0011 19.1 0.0 0.37 11.0 0.0 2.6 2 0 0 2 2 2 2 Quercetinase C-terminal cupin domain DUF570 PF04489.13 EKX32526.1 - 0.092 11.4 0.0 3 6.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF570) SUIM_assoc PF16619.5 EKX32526.1 - 1.9 8.6 11.3 0.12 12.5 5.2 2.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Metallophos PF00149.28 EKX32528.1 - 2.3e-16 60.9 0.0 4.7e-16 59.9 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EKX32528.1 - 1.9e-07 31.4 0.0 5.7e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Myc_N PF01056.18 EKX32528.1 - 5 6.9 8.2 2.1 8.2 5.7 1.6 2 0 0 2 2 2 0 Myc amino-terminal region Sec34 PF04136.15 EKX32529.1 - 0.017 15.0 0.5 0.03 14.2 0.5 1.3 1 0 0 1 1 1 0 Sec34-like family DUF3432 PF11914.8 EKX32530.1 - 8 6.8 32.3 21 5.4 6.3 3.9 1 1 2 3 3 3 0 Domain of unknown function (DUF3432) Ribosomal_60s PF00428.19 EKX32531.1 - 1.4e-22 80.1 8.9 1.6e-22 79.9 8.9 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Chorion_3 PF05387.11 EKX32531.1 - 0.14 11.8 5.2 0.14 11.8 5.2 1.3 1 0 0 1 1 1 0 Chorion family 3 HK PF02110.15 EKX32533.1 - 4.5e-32 111.4 0.2 5e-32 111.2 0.2 1.0 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family DUF4834 PF16118.5 EKX32536.1 - 0.044 14.7 0.2 0.044 14.7 0.2 5.6 2 2 2 4 4 4 0 Domain of unknown function (DUF4834) zinc_ribbon_5 PF13719.6 EKX32537.1 - 0.32 10.8 1.6 0.61 9.9 1.6 1.4 1 0 0 1 1 1 0 zinc-ribbon domain AAA PF00004.29 EKX32538.1 - 5.4e-36 123.9 0.0 7.7e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EKX32538.1 - 3.8e-10 39.4 0.0 7.4e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EKX32538.1 - 5.5e-05 23.5 0.1 0.00042 20.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EKX32538.1 - 8.2e-05 22.4 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EKX32538.1 - 0.00013 22.5 0.0 0.0005 20.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EKX32538.1 - 0.00023 21.6 0.0 0.00054 20.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EKX32538.1 - 0.0003 20.8 0.1 0.002 18.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Vps4_C PF09336.10 EKX32538.1 - 0.00049 20.0 0.0 0.0013 18.7 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.17 EKX32538.1 - 0.00089 19.0 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 EKX32538.1 - 0.0025 18.0 0.0 0.0056 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EKX32538.1 - 0.0066 15.9 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 EKX32538.1 - 0.0077 16.4 0.0 0.016 15.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 EKX32538.1 - 0.0081 15.4 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 EKX32538.1 - 0.016 15.6 0.0 0.039 14.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 EKX32538.1 - 0.017 14.6 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.6 EKX32538.1 - 0.019 15.0 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EKX32538.1 - 0.021 14.5 0.0 0.34 10.6 0.0 2.4 3 0 0 3 3 3 0 Sigma-54 interaction domain TsaE PF02367.17 EKX32538.1 - 0.022 14.8 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 EKX32538.1 - 0.024 14.0 0.2 0.72 9.2 0.1 2.2 1 1 1 2 2 2 0 KaiC AAA_7 PF12775.7 EKX32538.1 - 0.031 13.8 0.0 0.063 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 EKX32538.1 - 0.034 13.7 2.4 0.45 10.1 0.2 3.0 2 2 0 3 3 3 0 AAA domain AAA_28 PF13521.6 EKX32538.1 - 0.042 14.1 0.1 0.092 13.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EKX32538.1 - 0.061 13.0 0.1 0.11 12.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EKX32538.1 - 0.14 12.0 0.1 0.43 10.5 0.0 1.8 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.17 EKX32538.1 - 0.25 10.4 0.0 0.59 9.2 0.0 1.5 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 RCC1 PF00415.18 EKX32539.1 - 2.2e-50 169.1 17.7 2e-13 50.7 0.0 7.0 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX32539.1 - 2.3e-25 87.8 21.8 1.5e-05 24.6 1.4 7.4 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat PapC_C PF13953.6 EKX32539.1 - 0.045 13.6 3.4 3.5 7.5 0.0 3.0 4 0 0 4 4 4 0 PapC C-terminal domain WD40 PF00400.32 EKX32540.1 - 4.4e-15 55.8 6.9 0.014 16.2 0.9 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 EKX32540.1 - 0.028 13.1 1.6 0.74 8.4 1.7 2.4 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Dfp1_Him1_M PF08630.10 EKX32540.1 - 0.06 13.6 0.0 9 6.5 0.0 3.7 3 1 0 3 3 3 0 Dfp1/Him1, central region TerY_C PF15616.6 EKX32541.1 - 1.9 8.6 5.7 1.8 8.7 3.8 1.8 2 0 0 2 2 2 0 TerY-C metal binding domain Choline_kinase PF01633.20 EKX32543.1 - 1.3e-52 178.5 0.0 1.6e-52 178.2 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EKX32543.1 - 3.6e-09 36.9 0.0 4.3e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RFX5_N PF18326.1 EKX32543.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 RFX5 N-terminal domain EcKinase PF02958.20 EKX32543.1 - 0.13 11.5 0.2 0.24 10.7 0.2 1.4 1 1 0 1 1 1 0 Ecdysteroid kinase DUF1679 PF07914.11 EKX32543.1 - 0.16 10.8 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Thiolase_N PF00108.23 EKX32544.1 - 1.5e-89 299.8 0.3 2.4e-89 299.1 0.3 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EKX32544.1 - 7.8e-39 132.1 0.1 7.8e-39 132.1 0.1 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EKX32544.1 - 0.0003 20.5 0.8 0.00072 19.2 0.8 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EKX32544.1 - 0.25 11.2 3.6 7.3 6.5 0.1 3.4 3 1 1 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ubiquitin PF00240.23 EKX32546.1 - 2.3e-33 113.8 0.5 3.2e-33 113.3 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 EKX32546.1 - 1.1e-27 95.7 8.8 1.7e-27 95.1 8.8 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 EKX32546.1 - 3e-16 59.0 1.9 3.6e-16 58.8 0.7 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EKX32546.1 - 9.7e-05 22.7 0.1 0.00042 20.7 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EKX32546.1 - 0.0048 16.8 0.0 0.0064 16.4 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EKX32546.1 - 0.0082 16.5 0.1 0.016 15.5 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EKX32546.1 - 0.011 15.8 0.1 0.021 14.9 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EKX32546.1 - 0.034 14.7 0.0 0.04 14.5 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EKX32546.1 - 0.088 12.9 1.0 10 6.2 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain IFT43 PF15305.6 EKX32547.1 - 5.9e-13 49.2 4.1 2.5e-12 47.1 4.1 2.1 1 1 0 1 1 1 1 Intraflagellar transport protein 43 DUF599 PF04654.12 EKX32548.1 - 1.3e-14 54.2 6.4 1.9e-14 53.6 6.4 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF599 LIM PF00412.22 EKX32549.1 - 4.1e-20 71.8 21.2 1.3e-10 41.3 7.2 2.2 2 0 0 2 2 2 2 LIM domain DUF983 PF06170.12 EKX32549.1 - 0.02 15.3 2.0 4.6 7.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF983) zf-CCHC_5 PF14787.6 EKX32549.1 - 0.043 13.5 0.8 14 5.5 0.0 2.9 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Zn_Tnp_IS1595 PF12760.7 EKX32549.1 - 0.075 13.0 24.5 1.9 8.5 2.8 4.2 2 2 1 4 4 4 0 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.12 EKX32549.1 - 0.2 11.2 19.3 2.7 7.6 0.7 4.6 5 0 0 5 5 5 0 TFIIB zinc-binding Lar_restr_allev PF14354.6 EKX32549.1 - 0.55 10.6 17.6 6.5 7.2 5.1 3.4 2 2 0 2 2 2 0 Restriction alleviation protein Lar Papo_T_antigen PF02380.15 EKX32549.1 - 0.57 10.4 12.7 0.24 11.6 3.2 2.2 2 0 0 2 2 2 0 T-antigen specific domain zf_UBZ PF18439.1 EKX32549.1 - 0.78 9.4 16.5 0.91 9.2 0.1 4.6 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger YacG PF03884.14 EKX32549.1 - 1.6 8.5 5.1 11 5.8 0.2 2.8 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG Anti-TRAP PF15777.5 EKX32549.1 - 2.3 8.3 11.1 7.7 6.6 0.1 4.1 3 1 1 4 4 4 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-FPG_IleRS PF06827.14 EKX32549.1 - 8.4 6.4 17.2 0.96 9.4 1.1 4.0 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS Cyclin PF08613.11 EKX32551.1 - 2.5e-25 89.7 0.0 4.1e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EKX32551.1 - 8.2e-06 25.6 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain F5_F8_type_C PF00754.25 EKX32552.1 - 1.7e-19 70.2 0.0 3.3e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain HMG_box PF00505.19 EKX32552.1 - 4.8e-05 23.7 1.2 0.00013 22.3 1.2 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box RAMA PF18755.1 EKX32552.1 - 0.00054 20.3 0.0 0.0017 18.7 0.0 1.8 1 0 0 1 1 1 1 Restriction Enzyme Adenine Methylase Associated HMG_box_2 PF09011.10 EKX32552.1 - 0.0021 18.6 1.7 0.007 16.9 1.7 1.9 1 0 0 1 1 1 1 HMG-box domain DZR PF12773.7 EKX32552.1 - 0.059 13.4 3.2 0.052 13.6 1.1 1.9 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 EKX32552.1 - 0.98 9.2 5.1 3.4 7.5 5.1 2.0 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 EKX32552.1 - 3.9 7.0 6.4 0.61 9.6 1.5 2.3 3 0 0 3 3 3 0 zinc-ribbon domain DSPc PF00782.20 EKX32553.1 - 3.8e-08 33.2 0.0 5e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EKX32553.1 - 0.00011 22.3 0.0 0.00015 21.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EKX32553.1 - 0.00015 21.4 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX32553.1 - 0.0023 18.1 0.0 0.0032 17.6 0.0 1.4 1 1 0 1 1 1 1 Inositol hexakisphosphate TPR_19 PF14559.6 EKX32555.1 - 5.7e-06 26.7 4.4 0.065 13.8 0.0 5.0 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX32555.1 - 1e-05 25.9 0.0 0.51 11.3 0.0 5.7 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX32555.1 - 0.00026 20.9 6.7 1.4 9.2 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX32555.1 - 0.003 18.1 2.7 16 6.4 0.0 5.6 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX32555.1 - 0.025 14.4 4.0 27 4.8 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 EKX32555.1 - 0.11 12.9 0.5 1.8 9.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF349 PF03993.12 EKX32555.1 - 0.12 12.7 0.1 0.12 12.7 0.1 2.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) Vasculin PF15337.6 EKX32555.1 - 0.12 13.2 0.1 0.37 11.7 0.1 1.8 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 ANAPC3 PF12895.7 EKX32555.1 - 0.76 10.0 6.9 1.6 9.0 0.1 4.0 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Asp PF00026.23 EKX32556.1 - 1.3e-15 57.6 0.0 1.3e-06 28.1 0.0 3.2 3 1 0 3 3 3 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EKX32556.1 - 0.00024 21.4 0.1 0.0091 16.2 0.0 2.3 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal DNA_pol_B_thumb PF14791.6 EKX32556.1 - 0.15 12.2 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase beta thumb PPR_1 PF12854.7 EKX32557.1 - 0.034 13.8 5.2 40 4.0 0.1 5.1 3 0 0 3 3 3 0 PPR repeat DIOX_N PF14226.6 EKX32557.1 - 0.045 14.5 0.8 2e+02 2.8 0.0 4.3 4 1 1 5 5 5 0 non-haem dioxygenase in morphine synthesis N-terminal Apc13p PF05839.11 EKX32558.1 - 4.2e-07 30.1 6.6 2.9e-06 27.4 6.6 1.9 1 1 0 1 1 1 1 Apc13p protein NOA36 PF06524.12 EKX32558.1 - 6.7 5.9 6.6 6.2 6.0 6.6 1.0 1 0 0 1 1 1 0 NOA36 protein PhoD PF09423.10 EKX32559.1 - 3.3e-70 236.9 0.3 4.2e-70 236.5 0.3 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 EKX32559.1 - 8.1e-07 29.5 0.0 1.5e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 EKX32559.1 - 0.11 13.0 0.0 0.2 12.3 0.0 1.4 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain Methyltr_RsmB-F PF01189.17 EKX32561.1 - 1.7e-37 129.0 0.1 2e-36 125.5 0.1 2.1 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EKX32561.1 - 0.00024 21.3 0.0 0.00044 20.4 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase FoP_duplication PF13865.6 EKX32561.1 - 0.32 11.6 11.0 0.55 10.8 11.0 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Death PF00531.22 EKX32562.1 - 0.17 12.1 5.8 4.3 7.6 0.1 2.8 1 1 2 3 3 3 0 Death domain AAA PF00004.29 EKX32563.1 - 7e-37 126.8 0.0 1.3e-36 125.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EKX32563.1 - 1.9e-09 37.1 0.0 4.6e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EKX32563.1 - 1.8e-06 27.8 0.0 3.7e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EKX32563.1 - 2.7e-05 24.2 0.0 0.0002 21.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EKX32563.1 - 4.2e-05 23.8 0.7 0.029 14.6 0.0 3.5 2 1 2 4 4 4 1 AAA domain AAA_14 PF13173.6 EKX32563.1 - 9.1e-05 22.5 0.0 0.00021 21.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EKX32563.1 - 0.00014 22.0 0.0 0.00043 20.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EKX32563.1 - 0.00017 22.0 3.5 0.0015 18.9 0.0 3.1 3 1 1 4 4 3 1 AAA ATPase domain AAA_18 PF13238.6 EKX32563.1 - 0.00083 19.9 0.1 0.0019 18.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 EKX32563.1 - 0.00087 19.1 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 EKX32563.1 - 0.00093 18.4 0.1 0.0025 16.9 0.0 1.6 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 DUF815 PF05673.13 EKX32563.1 - 0.00097 18.4 0.0 0.0017 17.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EKX32563.1 - 0.0011 19.4 0.0 0.0078 16.6 0.0 2.3 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 EKX32563.1 - 0.0019 18.0 0.0 0.0043 16.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EKX32563.1 - 0.002 17.6 0.0 0.0045 16.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EKX32563.1 - 0.002 17.7 0.1 0.019 14.5 0.0 2.4 2 2 0 2 2 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 EKX32563.1 - 0.0023 18.2 0.0 0.0047 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EKX32563.1 - 0.0032 17.4 1.0 0.063 13.2 0.0 2.6 2 1 1 3 3 2 1 NACHT domain TIP49 PF06068.13 EKX32563.1 - 0.0084 15.4 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 EKX32563.1 - 0.009 16.1 0.0 0.035 14.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) TniB PF05621.11 EKX32563.1 - 0.012 15.0 0.1 2.5 7.5 0.0 2.7 2 1 1 3 3 2 0 Bacterial TniB protein Bac_DnaA PF00308.18 EKX32563.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_30 PF13604.6 EKX32563.1 - 0.056 13.2 0.0 0.79 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EKX32563.1 - 0.057 13.1 0.0 0.26 11.0 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain Cons_hypoth698 PF03601.14 EKX32563.1 - 0.097 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 698 MMR_HSR1 PF01926.23 EKX32563.1 - 0.12 12.5 0.2 1.5 8.9 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.27 EKX32563.1 - 0.13 12.8 0.0 0.26 11.8 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AFG1_ATPase PF03969.16 EKX32563.1 - 0.13 11.1 0.0 0.24 10.3 0.0 1.5 1 0 0 1 1 1 0 AFG1-like ATPase AAA_17 PF13207.6 EKX32563.1 - 0.14 12.6 0.2 0.6 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EKX32563.1 - 0.14 11.7 0.1 0.67 9.5 0.1 2.0 1 1 1 2 2 2 0 AAA domain Glyoxalase PF00903.25 EKX32564.1 - 2.1e-26 92.6 0.6 3.9e-18 65.9 0.0 2.7 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EKX32564.1 - 9.5e-11 41.9 0.3 0.00056 20.2 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 EKX32564.1 - 4.4e-08 33.4 0.2 5.2e-07 29.9 0.2 2.2 2 1 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 EKX32564.1 - 0.0016 18.5 0.1 1 9.4 0.0 3.7 3 2 0 3 3 3 1 Glyoxalase-like domain Rtt106 PF08512.12 EKX32564.1 - 0.047 14.1 0.0 0.09 13.2 0.0 1.5 1 0 0 1 1 1 0 Histone chaperone Rttp106-like Gemini_C4 PF01492.17 EKX32564.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Geminivirus C4 protein RIC1 PF07064.13 EKX32565.1 - 4.6e-06 26.2 0.0 7.8e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 RIC1 Na_trans_assoc PF06512.13 EKX32567.1 - 0.57 10.4 9.5 0.78 10.0 9.5 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated RR_TM4-6 PF06459.12 EKX32567.1 - 6.5 6.5 18.2 7.6 6.3 18.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Abhydrolase_1 PF00561.20 EKX32569.1 - 1.1e-05 25.2 0.6 0.0053 16.4 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EKX32569.1 - 8.7e-05 21.9 0.1 0.042 13.1 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EKX32569.1 - 0.00028 21.6 1.8 0.0012 19.5 1.9 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EKX32569.1 - 0.002 17.6 0.0 0.0059 16.1 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EKX32569.1 - 0.0027 17.6 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DUF818 PF05677.12 EKX32569.1 - 0.011 14.7 0.0 0.049 12.6 0.0 1.8 1 1 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) DLH PF01738.18 EKX32569.1 - 0.012 15.1 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family FSH1 PF03959.13 EKX32569.1 - 0.036 13.7 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) LIP PF03583.14 EKX32569.1 - 0.041 13.2 0.1 0.61 9.3 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase zf-RING_2 PF13639.6 EKX32570.1 - 1.1e-12 48.1 11.6 1.1e-12 48.1 11.6 2.7 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX32570.1 - 6e-10 38.8 11.0 6e-10 38.8 11.0 2.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EKX32570.1 - 3.5e-09 36.2 2.0 3.5e-09 36.2 2.0 2.8 3 0 0 3 3 3 1 RING-like zinc finger zf-rbx1 PF12678.7 EKX32570.1 - 1.1e-06 28.8 17.1 1.9e-06 28.0 14.2 2.8 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EKX32570.1 - 1.2e-06 28.4 6.1 1.2e-06 28.4 6.1 3.2 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 EKX32570.1 - 2.4e-06 27.4 8.1 2.4e-06 27.4 8.1 2.8 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EKX32570.1 - 1.6e-05 24.7 10.6 1.6e-05 24.7 10.6 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EKX32570.1 - 2.7e-05 24.2 4.9 3.5e-05 23.8 3.1 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EKX32570.1 - 3.1e-05 23.7 15.0 6.5e-05 22.7 7.4 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 EKX32570.1 - 0.00041 20.5 2.0 0.00041 20.5 2.0 4.3 3 1 0 3 3 3 1 zinc-ribbon Zn_ribbon_17 PF17120.5 EKX32570.1 - 0.0056 16.3 5.7 0.0056 16.3 5.7 2.0 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-BED PF02892.15 EKX32570.1 - 0.017 15.1 1.6 2.1 8.5 0.0 3.3 3 0 0 3 3 3 0 BED zinc finger Prok-RING_4 PF14447.6 EKX32570.1 - 0.38 10.7 24.2 0.36 10.7 15.3 3.6 3 1 1 4 4 4 0 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 EKX32570.1 - 0.49 10.3 6.1 9.7 6.1 1.0 3.1 3 0 0 3 3 3 0 Rad50 zinc hook motif zinc_ribbon_16 PF17034.5 EKX32570.1 - 1.4 9.1 10.4 2.3 8.5 4.6 2.9 3 0 0 3 3 3 0 Zinc-ribbon like family DZR PF12773.7 EKX32570.1 - 1.8 8.7 13.9 3.7 7.7 0.6 2.9 2 1 0 2 2 2 0 Double zinc ribbon zf-TFIIB PF13453.6 EKX32570.1 - 4.9 6.6 18.4 1 8.8 0.1 4.3 4 0 0 4 4 4 0 Transcription factor zinc-finger Zn_ribbon_SprT PF17283.2 EKX32570.1 - 6.2 6.8 9.5 12 5.9 0.1 4.0 4 0 0 4 4 4 0 SprT-like zinc ribbon domain SNARE_assoc PF09335.11 EKX32571.1 - 1.6e-20 73.8 5.9 1.6e-20 73.8 5.9 1.9 1 1 0 1 1 1 1 SNARE associated Golgi protein DUF962 PF06127.11 EKX32571.1 - 0.23 11.6 2.8 0.5 10.5 2.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF962) Ion_trans PF00520.31 EKX32572.1 - 8.7e-06 25.1 4.7 1.8e-05 24.1 4.7 1.6 1 0 0 1 1 1 1 Ion transport protein Cwf_Cwc_15 PF04889.12 EKX32572.1 - 0.87 9.3 7.2 1.5 8.5 7.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 EKX32573.1 - 0.013 13.8 9.1 0.01 14.1 9.1 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 EKX32573.1 - 0.015 13.8 4.5 0.014 13.9 4.5 1.0 1 0 0 1 1 1 0 Mpp10 protein DUF2796 PF10986.8 EKX32573.1 - 0.024 14.6 0.2 0.03 14.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) SDA1 PF05285.12 EKX32573.1 - 0.04 13.3 9.1 0.035 13.5 9.1 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 EKX32573.1 - 0.27 10.5 8.2 0.27 10.5 8.2 1.1 1 0 0 1 1 1 0 BUD22 CNDH2_C PF16858.5 EKX32573.1 - 1 9.2 6.4 0.94 9.3 6.4 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Pes-10 PF07149.11 EKX32573.1 - 2.8 6.9 10.4 2.7 7.0 10.4 1.1 1 0 0 1 1 1 0 Pes-10 DUF5520 PF17658.1 EKX32573.1 - 7.7 5.5 5.5 11 5.0 5.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5520) CobT PF06213.12 EKX32573.1 - 9.4 5.5 14.8 12 5.2 14.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT ADH_zinc_N PF00107.26 EKX32574.1 - 4.2e-27 94.7 0.0 7.1e-27 94.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EKX32574.1 - 3.8e-14 53.9 0.0 9e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EKX32574.1 - 2.1e-10 40.4 0.1 3.5e-09 36.5 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EKX32574.1 - 0.0011 18.4 0.9 0.0026 17.3 0.9 1.6 1 1 1 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.6 EKX32574.1 - 0.0029 17.5 0.2 0.0044 16.9 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Eno-Rase_NADH_b PF12242.8 EKX32574.1 - 0.0041 16.9 0.4 0.0093 15.7 0.4 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AlaDh_PNT_C PF01262.21 EKX32574.1 - 0.0058 16.0 0.3 0.0096 15.2 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.21 EKX32574.1 - 0.055 13.2 0.1 0.087 12.5 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase PALP PF00291.25 EKX32574.1 - 0.062 12.7 0.2 0.1 12.0 0.2 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme adh_short_C2 PF13561.6 EKX32574.1 - 0.5 9.9 3.2 6.8 6.2 0.0 2.2 1 1 1 2 2 2 0 Enoyl-(Acyl carrier protein) reductase UQ_con PF00179.26 EKX32575.1 - 2.3e-30 105.1 0.0 2.7e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EKX32575.1 - 2.8e-05 23.9 0.0 3.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UFC1 PF08694.11 EKX32575.1 - 0.0022 17.7 0.0 0.0037 16.9 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 EKX32575.1 - 0.039 14.3 0.0 0.045 14.1 0.0 1.4 1 0 0 1 1 1 0 RWD domain Prok-E2_A PF14457.6 EKX32575.1 - 0.11 12.1 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family A Ion_trans PF00520.31 EKX32576.1 - 6e-81 271.3 38.9 1.4e-41 142.4 13.9 2.8 2 1 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 EKX32576.1 - 4.8 5.8 41.8 0.13 10.9 3.1 6.4 5 3 2 8 8 8 0 Polycystin cation channel YidD PF01809.18 EKX32577.1 - 3.2e-22 78.2 0.0 3.7e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Putative membrane protein insertion efficiency factor Cyclin PF08613.11 EKX32578.1 - 4e-23 82.5 0.0 4.3e-23 82.5 0.0 1.0 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EKX32578.1 - 0.00089 19.0 0.0 0.001 18.8 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ketoacyl-synt_C PF02801.22 EKX32579.1 - 1.3e-28 99.4 0.1 3.2e-28 98.1 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 EKX32579.1 - 3.1e-28 99.0 4.6 4.3e-19 69.1 0.1 2.5 3 0 0 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain KAsynt_C_assoc PF16197.5 EKX32579.1 - 0.075 13.5 0.0 0.3 11.5 0.0 2.0 2 0 0 2 2 2 0 Ketoacyl-synthetase C-terminal extension cNMPbd_u2 PF16643.5 EKX32581.1 - 0.08 13.4 0.1 0.18 12.3 0.1 1.5 1 0 0 1 1 1 0 Unstructured region on cNMP-binding protein Benyvirus_14KDa PF07255.11 EKX32582.1 - 0.049 13.8 1.9 2.8 8.2 0.8 2.2 2 0 0 2 2 2 0 Benyvirus 14KDa protein bVLRF1 PF18826.1 EKX32582.1 - 0.19 11.6 0.3 0.34 10.8 0.1 1.5 2 0 0 2 2 2 0 bacteroidetes VLRF1 release factor DDHD PF02862.17 EKX32583.1 - 0.16 12.1 4.9 4.2 7.5 2.9 2.6 3 0 0 3 3 3 0 DDHD domain Ank_5 PF13857.6 EKX32585.1 - 7.8e-10 38.8 0.0 2.6e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX32585.1 - 2.2e-07 31.4 0.0 8e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX32585.1 - 1.9e-06 28.3 0.0 4.7e-06 27.0 0.0 1.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX32585.1 - 2.1e-06 27.6 0.0 0.003 17.9 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EKX32585.1 - 8.4e-05 22.8 0.0 0.0016 18.8 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat DUF444 PF04285.12 EKX32585.1 - 3.9 6.4 5.9 4.9 6.1 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF444) IP_trans PF02121.18 EKX32587.1 - 5.4e-36 124.4 0.8 5.4e-36 124.4 0.8 2.0 1 1 1 2 2 1 1 Phosphatidylinositol transfer protein DUF4604 PF15377.6 EKX32587.1 - 0.0014 19.0 7.9 0.0021 18.5 7.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DUF1645 PF07816.11 EKX32587.1 - 0.0019 18.8 2.5 0.0028 18.3 2.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) Ycf1 PF05758.12 EKX32587.1 - 0.0041 15.1 7.4 0.0064 14.4 7.4 1.2 1 0 0 1 1 1 1 Ycf1 Connexin PF00029.19 EKX32587.1 - 0.0053 16.6 4.4 0.0053 16.6 4.4 1.6 2 0 0 2 2 2 1 Connexin DUF2075 PF09848.9 EKX32587.1 - 0.0069 15.7 2.1 0.0083 15.4 2.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) RHD_DNA_bind PF00554.22 EKX32587.1 - 0.0075 16.2 3.3 0.0075 16.2 3.3 1.6 2 0 0 2 2 2 1 Rel homology DNA-binding domain DUF2615 PF11027.8 EKX32587.1 - 0.0088 16.2 2.0 0.015 15.4 2.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) GPDPase_memb PF10110.9 EKX32587.1 - 0.043 12.6 1.9 0.054 12.3 1.9 1.1 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase FHIPEP PF00771.20 EKX32587.1 - 0.052 12.0 2.8 0.07 11.6 2.8 1.1 1 0 0 1 1 1 0 FHIPEP family Rot1 PF10681.9 EKX32587.1 - 0.066 12.7 4.8 0.13 11.8 4.8 1.4 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal OATP PF03137.20 EKX32587.1 - 0.13 10.6 3.9 0.17 10.2 3.9 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family OAD_gamma PF04277.13 EKX32587.1 - 0.15 12.6 7.1 0.31 11.7 7.1 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain PigN PF04987.14 EKX32587.1 - 0.2 10.4 0.5 0.28 10.0 0.5 1.1 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) TMEM164 PF14808.6 EKX32587.1 - 0.23 10.8 2.9 0.33 10.3 2.9 1.1 1 0 0 1 1 1 0 TMEM164 family EphA2_TM PF14575.6 EKX32587.1 - 0.28 12.1 2.9 0.6 11.0 2.9 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain O-ag_pol_Wzy PF14296.6 EKX32587.1 - 0.5 9.0 3.9 0.68 8.5 3.9 1.1 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy DUF819 PF05684.12 EKX32587.1 - 0.57 9.2 3.0 0.72 8.8 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF819) AP3D1 PF06375.11 EKX32587.1 - 1.1 9.4 22.2 0.62 10.3 16.4 2.1 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 DUF3464 PF11947.8 EKX32587.1 - 1.3 8.7 7.5 2.5 7.8 7.5 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Folate_carrier PF01770.18 EKX32587.1 - 1.4 7.5 4.9 1.9 7.1 4.9 1.1 1 0 0 1 1 1 0 Reduced folate carrier Porph_ging PF09697.10 EKX32587.1 - 2.8 8.5 8.6 0.55 10.8 4.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (Porph_ging) Rsc14 PF08586.10 EKX32587.1 - 2.9 8.7 6.4 5.7 7.8 3.7 2.1 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit SLD3 PF08639.10 EKX32587.1 - 3.4 6.3 15.2 5.2 5.7 15.2 1.2 1 0 0 1 1 1 0 DNA replication regulator SLD3 DUF1764 PF08576.10 EKX32587.1 - 3.7 8.5 14.4 6.4 7.7 11.5 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Rrn6 PF10214.9 EKX32588.1 - 7.4 4.9 10.4 8.7 4.7 10.4 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor WD40 PF00400.32 EKX32589.1 - 2.2e-57 189.7 51.9 1.7e-06 28.6 0.0 20.7 21 1 0 21 21 21 13 WD domain, G-beta repeat HELP PF03451.14 EKX32589.1 - 5.9e-25 86.9 0.0 2e-12 46.8 0.0 2.3 2 0 0 2 2 2 2 HELP motif ANAPC4_WD40 PF12894.7 EKX32589.1 - 2.9e-20 72.4 7.3 0.0027 18.0 0.0 10.9 5 3 6 12 12 12 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EKX32589.1 - 4.5e-09 36.1 0.2 0.4 10.0 0.0 5.4 4 1 1 5 5 5 4 WD40-like domain BBS2_Mid PF14783.6 EKX32589.1 - 0.064 13.3 0.0 11 6.1 0.0 3.8 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region PD40 PF07676.12 EKX32589.1 - 0.11 12.5 0.0 16 5.6 0.0 3.1 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat VID27 PF08553.10 EKX32589.1 - 0.11 11.5 0.0 28 3.6 0.0 3.2 3 0 0 3 3 3 0 VID27 C-terminal WD40-like domain PH PF00169.29 EKX32590.1 - 0.00017 22.1 0.0 0.00017 22.1 0.0 2.2 3 0 0 3 3 3 1 PH domain Ion_trans PF00520.31 EKX32590.1 - 0.0046 16.2 1.7 0.007 15.6 1.7 1.2 1 0 0 1 1 1 1 Ion transport protein PDZ_2 PF13180.6 EKX32591.1 - 0.0012 19.1 0.0 0.0033 17.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX32591.1 - 0.0097 16.2 0.0 0.022 15.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain T3SSipB PF16535.5 EKX32591.1 - 0.55 10.7 0.0 0.55 10.7 0.0 3.2 4 1 0 4 4 4 0 Type III cell invasion protein SipB Swi5 PF07061.11 EKX32591.1 - 6.6 6.9 7.3 12 6.0 0.4 3.7 4 0 0 4 4 4 0 Swi5 WW PF00397.26 EKX32592.1 - 8.6e-09 35.3 1.2 1.5e-08 34.6 0.1 1.9 2 0 0 2 2 2 1 WW domain Tmemb_cc2 PF10267.9 EKX32592.1 - 1.6e-05 24.2 0.1 1.6e-05 24.2 0.1 1.9 2 0 0 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein Dynamitin PF04912.14 EKX32592.1 - 0.012 14.9 0.4 0.012 14.9 0.4 2.0 2 0 0 2 2 2 0 Dynamitin DUF1664 PF07889.12 EKX32592.1 - 0.024 14.7 0.9 0.024 14.7 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Collagen PF01391.18 EKX32592.1 - 0.079 12.7 2.5 0.14 11.9 2.5 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Tau95 PF09734.9 EKX32592.1 - 0.094 13.5 0.3 0.094 13.5 0.3 2.0 2 0 0 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain HalX PF08663.10 EKX32592.1 - 0.13 12.6 3.2 2.4 8.5 0.1 2.4 1 1 1 2 2 2 0 HalX domain Rootletin PF15035.6 EKX32592.1 - 0.58 10.2 13.9 0.64 10.0 6.7 2.3 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Cytochrom_B562 PF07361.11 EKX32592.1 - 1.1 10.0 7.6 0.19 12.4 0.9 2.3 2 0 0 2 2 2 0 Cytochrome b562 Occludin_ELL PF07303.13 EKX32592.1 - 1.2 9.9 13.8 0.062 14.0 2.0 2.6 2 1 0 2 2 2 0 Occludin homology domain Fib_alpha PF08702.10 EKX32592.1 - 1.3 9.2 6.1 1 9.5 0.3 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 EKX32592.1 - 1.7 9.4 5.7 3.6 8.3 0.3 3.1 2 1 1 3 3 3 0 SlyX Prominin PF05478.11 EKX32592.1 - 1.8 6.4 5.0 0.91 7.4 0.4 2.0 2 0 0 2 2 2 0 Prominin Com_YlbF PF06133.11 EKX32592.1 - 4.9 7.8 11.4 0.24 12.0 2.3 2.4 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA FliL PF03748.14 EKX32592.1 - 7.4 7.2 6.6 11 6.6 0.4 2.6 2 1 0 2 2 2 0 Flagellar basal body-associated protein FliL TPR_12 PF13424.6 EKX32593.1 - 8.3e-09 35.6 0.0 2.5e-05 24.5 0.0 5.2 5 3 1 6 6 6 3 Tetratricopeptide repeat HLH PF00010.26 EKX32593.1 - 0.0009 19.2 0.1 0.0027 17.6 0.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TPR_10 PF13374.6 EKX32593.1 - 0.0065 16.3 4.7 1.1 9.2 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat Lambda_Kil PF06301.11 EKX32593.1 - 0.01 15.4 0.0 0.025 14.2 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage lambda Kil protein DUF2225 PF09986.9 EKX32593.1 - 0.03 14.0 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) ABM PF03992.16 EKX32594.1 - 9.1e-17 61.0 1.8 5.3e-12 45.7 0.2 2.6 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase DUF5517 PF17639.2 EKX32595.1 - 0.22 11.9 0.9 27 5.1 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5517) DUF2388 PF09498.10 EKX32595.1 - 8.5 6.4 10.5 10 6.2 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2388) Cadherin_3 PF16184.5 EKX32596.1 - 6.8e-08 32.5 2.4 0.16 12.0 0.0 5.2 4 0 0 4 4 4 3 Cadherin-like Cadherin_4 PF17803.1 EKX32596.1 - 2.6e-05 24.8 14.5 2.8 8.6 0.3 6.0 5 0 0 5 5 5 4 Bacterial cadherin-like domain Halogen_Hydrol PF10112.9 EKX32596.1 - 3.5 7.6 6.5 21 5.1 0.6 2.7 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DnaJ PF00226.31 EKX32597.1 - 4.6e-23 81.1 0.3 1.3e-22 79.7 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 EKX32597.1 - 1.9e-21 74.4 10.1 4.6e-06 26.3 0.1 8.1 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 EKX32597.1 - 9e-19 66.5 8.1 2.4e-06 27.1 0.0 7.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX32597.1 - 1.5e-09 37.9 7.6 0.13 13.1 0.4 6.7 3 3 4 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX32597.1 - 1.7e-06 28.4 3.7 0.2 12.2 0.1 4.8 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX32597.1 - 5.9e-06 26.1 5.3 0.26 11.6 0.0 6.3 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX32597.1 - 1.1e-05 25.0 1.5 0.045 13.5 0.1 5.3 6 1 1 7 7 7 1 TPR repeat TPR_9 PF13371.6 EKX32597.1 - 1.5e-05 25.1 4.8 2.1e-05 24.6 0.3 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX32597.1 - 0.00015 22.3 1.3 0.012 16.3 0.0 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat zf-RING_5 PF14634.6 EKX32597.1 - 0.00047 20.0 2.6 0.0012 18.8 2.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain TPR_12 PF13424.6 EKX32597.1 - 0.0014 18.9 15.2 0.75 10.1 1.1 5.3 3 2 1 5 5 5 3 Tetratricopeptide repeat NARP1 PF12569.8 EKX32597.1 - 0.0035 16.3 13.8 0.76 8.6 0.0 3.5 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 EKX32597.1 - 0.0036 17.6 3.4 0.44 10.9 0.3 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX32597.1 - 0.0038 17.4 0.3 0.0038 17.4 0.3 3.8 3 2 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 Vps54_N PF10475.9 EKX32597.1 - 0.021 14.1 0.1 0.063 12.6 0.0 1.8 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex TPR_7 PF13176.6 EKX32597.1 - 0.024 14.7 6.7 0.31 11.1 0.3 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 EKX32597.1 - 0.032 14.6 0.6 8.4 7.0 0.0 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat Phage_Gp23 PF10669.9 EKX32597.1 - 0.056 13.8 5.9 0.27 11.6 5.9 2.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) RPN7 PF10602.9 EKX32597.1 - 0.081 12.6 3.4 0.12 12.1 0.9 2.4 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_10 PF13374.6 EKX32597.1 - 0.16 11.9 8.2 14 5.7 0.6 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.6 EKX32597.1 - 0.69 9.8 5.4 2.6 8.0 5.4 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_6 PF13174.6 EKX32597.1 - 1.1 10.1 4.0 49 4.9 0.2 4.6 4 0 0 4 4 3 0 Tetratricopeptide repeat zf-C3HC4_2 PF13923.6 EKX32597.1 - 3.9 7.4 5.1 3.1 7.7 1.6 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_4 PF07721.14 EKX32597.1 - 6.6 7.7 7.9 9.3 7.2 0.2 4.5 5 0 0 5 5 3 0 Tetratricopeptide repeat Methyltransf_16 PF10294.9 EKX32598.1 - 2.2e-14 53.5 0.0 2.9e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EKX32598.1 - 2.7e-05 24.0 0.0 7.7e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX32598.1 - 0.00033 21.3 0.2 0.0032 18.1 0.2 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX32598.1 - 0.0023 17.7 0.0 1.6 8.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 EKX32598.1 - 0.0035 18.0 0.1 0.0094 16.6 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EKX32598.1 - 0.0035 16.9 0.1 0.0063 16.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 EKX32598.1 - 0.022 13.9 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase MetW PF07021.12 EKX32598.1 - 0.035 13.7 0.1 0.096 12.3 0.1 1.6 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW RrnaAD PF00398.20 EKX32598.1 - 0.041 12.9 0.0 0.057 12.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PrmA PF06325.13 EKX32598.1 - 0.079 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Glyco_transf_49 PF13896.6 EKX32600.1 - 1.9e-27 96.5 0.0 8.5e-25 87.8 0.0 2.4 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 EKX32600.1 - 0.079 12.8 0.0 0.22 11.3 0.0 1.7 1 1 1 2 2 2 0 Glycosyl transferase family 2 CNDH2_N PF06278.11 EKX32603.1 - 1.6e-39 134.6 0.4 1.6e-39 134.6 0.4 2.2 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal CNDH2_C PF16858.5 EKX32603.1 - 3.1e-29 102.8 0.0 3.1e-29 102.8 0.0 4.1 1 1 2 3 3 3 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term LSM PF01423.22 EKX32604.1 - 8.8e-18 63.8 0.2 1.1e-17 63.5 0.2 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EKX32604.1 - 0.0068 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Hfq protein MORN PF02493.20 EKX32605.1 - 1.2e-60 197.9 62.0 3.4e-09 36.1 1.0 10.1 10 0 0 10 10 10 10 MORN repeat DUF448 PF04296.13 EKX32605.1 - 0.0085 15.9 1.0 3 7.8 0.1 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF448) Peptidase_S55 PF05580.12 EKX32605.1 - 0.93 9.4 7.3 3 7.7 0.2 4.0 3 2 2 5 5 5 0 SpoIVB peptidase S55 ECR1_N PF14382.6 EKX32605.1 - 2.5 8.0 9.2 11 5.9 0.0 3.6 3 1 0 3 3 3 0 Exosome complex exonuclease RRP4 N-terminal region Hexokinase_2 PF03727.16 EKX32606.1 - 1.4e-37 129.4 0.8 2.9e-37 128.4 0.8 1.5 1 1 0 1 1 1 1 Hexokinase Sigma70_ner PF04546.13 EKX32607.1 - 0.002 18.1 11.5 0.0032 17.4 11.5 1.3 1 0 0 1 1 1 1 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.12 EKX32607.1 - 0.0049 16.7 11.4 0.0065 16.2 11.4 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 EKX32607.1 - 0.0062 14.8 9.5 0.0068 14.7 9.5 1.1 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.10 EKX32607.1 - 0.015 14.6 8.0 0.019 14.3 8.0 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 EKX32607.1 - 0.016 13.5 5.0 0.017 13.4 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 EKX32607.1 - 0.02 15.0 8.7 0.024 14.7 8.7 1.3 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.12 EKX32607.1 - 0.044 13.2 11.1 0.053 13.0 11.1 1.2 1 0 0 1 1 1 0 SDA1 zf-C5HC2 PF02928.16 EKX32607.1 - 0.098 13.1 0.0 0.098 13.1 0.0 2.3 2 0 0 2 2 1 0 C5HC2 zinc finger Zf_RING PF16744.5 EKX32607.1 - 0.17 12.0 4.5 0.15 12.2 2.7 1.8 2 0 0 2 2 2 0 KIAA1045 RING finger Pox_Ag35 PF03286.14 EKX32607.1 - 0.17 11.6 11.6 0.27 11.0 11.6 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF913 PF06025.12 EKX32607.1 - 0.19 10.7 2.3 0.27 10.2 2.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zn_ribbon_17 PF17120.5 EKX32607.1 - 0.3 10.8 6.2 0.71 9.5 6.2 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RRN3 PF05327.11 EKX32607.1 - 0.46 9.0 6.5 0.57 8.7 6.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HNF-1_N PF04814.13 EKX32607.1 - 0.53 10.9 6.0 0.93 10.1 6.0 1.3 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Zip PF02535.22 EKX32607.1 - 0.58 9.3 1.3 0.65 9.2 1.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Merozoite_SPAM PF07133.11 EKX32607.1 - 2.5 8.1 24.8 3.6 7.5 24.8 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) RXT2_N PF08595.11 EKX32607.1 - 2.6 8.1 9.5 4.5 7.3 9.5 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Sporozoite_P67 PF05642.11 EKX32607.1 - 3.3 5.7 10.5 4.4 5.3 10.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CENP-B_dimeris PF09026.10 EKX32607.1 - 6.3 7.3 17.6 14 6.1 17.6 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 EKX32607.1 - 7.1 4.6 20.8 9.3 4.2 20.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi PARP_regulatory PF01358.18 EKX32608.1 - 1.2e-19 70.3 0.0 1.5e-19 70.1 0.0 1.0 1 0 0 1 1 1 1 Poly A polymerase regulatory subunit Retrotrans_gag PF03732.17 EKX32611.1 - 0.0019 18.5 0.1 0.0073 16.6 0.1 2.0 1 0 0 1 1 1 1 Retrotransposon gag protein Kisspeptin PF15152.6 EKX32611.1 - 0.11 13.3 0.1 15 6.4 0.0 2.6 2 0 0 2 2 2 0 Kisspeptin IZUMO PF15005.6 EKX32611.1 - 0.19 12.3 1.5 0.37 11.3 0.3 2.1 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated PDZ_6 PF17820.1 EKX32613.1 - 1.7e-08 34.2 0.0 2.7e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX32613.1 - 9.9e-06 25.8 0.0 1.4e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX32613.1 - 2.4e-05 24.6 0.0 3.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX32613.1 - 0.017 15.0 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Tricorn protease PDZ domain BCSC_C PF05420.11 EKX32614.1 - 0.0075 15.5 0.4 0.013 14.6 0.4 1.3 1 0 0 1 1 1 1 Cellulose synthase operon protein C C-terminus (BCSC_C) FAM184 PF15665.5 EKX32615.1 - 0.81 9.4 51.4 1.3 8.8 20.5 3.2 2 1 1 3 3 3 0 Family with sequence similarity 184, A and B DUF3093 PF11292.8 EKX32617.1 - 0.041 14.2 0.0 0.052 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) Macoilin PF09726.9 EKX32618.1 - 9.4 4.7 13.6 12 4.3 13.6 1.1 1 0 0 1 1 1 0 Macoilin family YbbR PF07949.12 EKX32619.1 - 0.0039 17.5 0.0 31 5.0 0.0 3.9 1 1 1 3 3 3 1 YbbR-like protein DUF1799 PF08809.11 EKX32619.1 - 0.1 12.8 9.4 15 5.9 0.1 4.6 1 1 5 6 6 6 0 Phage related hypothetical protein (DUF1799) DUF3016 PF11454.8 EKX32619.1 - 0.47 10.2 4.1 13 5.5 0.2 3.1 1 1 3 4 4 4 0 Protein of unknown function (DUF3016) Kinase-like PF14531.6 EKX32619.1 - 2 7.6 6.6 12 5.1 0.1 2.9 1 1 1 3 3 3 0 Kinase-like RRM_7 PF16367.5 EKX32623.1 - 0.00046 20.2 0.0 0.00084 19.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif RRM_1 PF00076.22 EKX32623.1 - 0.00048 19.9 0.1 0.0022 17.8 0.1 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Herpes_LMP1 PF05297.11 EKX32623.1 - 0.031 13.5 3.9 0.048 12.9 3.9 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) SHE3 PF17078.5 EKX32624.1 - 0.0072 16.1 3.8 0.0072 16.1 3.8 2.1 1 1 1 2 2 2 1 SWI5-dependent HO expression protein 3 APG6_N PF17675.1 EKX32624.1 - 0.017 15.6 19.4 0.019 15.5 6.5 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Fmp27_WPPW PF10359.9 EKX32624.1 - 0.11 11.3 10.6 0.16 10.8 10.6 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Med4 PF10018.9 EKX32624.1 - 0.13 11.9 4.9 3.1 7.4 0.1 2.6 2 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF4743 PF15916.5 EKX32624.1 - 0.18 11.8 2.0 0.44 10.5 1.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4743) ZapB PF06005.12 EKX32624.1 - 0.25 11.8 18.6 0.46 10.9 5.2 2.5 1 1 1 2 2 2 0 Cell division protein ZapB DUF2353 PF09789.9 EKX32624.1 - 0.31 10.4 15.1 2.5 7.4 15.1 2.0 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Jnk-SapK_ap_N PF09744.9 EKX32624.1 - 0.89 9.8 16.7 0.43 10.8 5.1 2.3 1 1 0 2 2 2 0 JNK_SAPK-associated protein-1 DivIC PF04977.15 EKX32624.1 - 0.9 9.4 14.0 6.3 6.6 1.2 3.4 2 1 1 3 3 3 0 Septum formation initiator KASH_CCD PF14662.6 EKX32624.1 - 0.91 9.3 16.3 0.61 9.9 7.3 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH PCRF PF03462.18 EKX32624.1 - 1.3 8.8 10.9 4.8 7.0 1.4 2.2 1 1 1 2 2 2 0 PCRF domain Seryl_tRNA_N PF02403.22 EKX32624.1 - 1.8 8.9 9.5 2 8.7 1.3 2.8 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain JIP_LZII PF16471.5 EKX32624.1 - 3.9 7.7 16.5 2.7 8.2 1.4 4.1 3 1 1 4 4 4 0 JNK-interacting protein leucine zipper II RasGAP_C PF03836.15 EKX32624.1 - 5.9 7.0 14.7 3.4 7.8 4.5 2.2 1 1 1 2 2 2 0 RasGAP C-terminus Lzipper-MIP1 PF14389.6 EKX32625.1 - 0.076 13.3 1.0 0.18 12.1 1.0 1.6 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 CAMSAP_CC1 PF17095.5 EKX32625.1 - 3.8 7.4 8.6 5.2 7.0 3.6 2.5 2 0 0 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin Fib_alpha PF08702.10 EKX32626.1 - 0.03 14.5 20.4 0.049 13.8 2.5 4.3 2 2 1 4 4 4 0 Fibrinogen alpha/beta chain family DUF2783 PF10932.8 EKX32626.1 - 0.099 12.3 0.6 1 9.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2783) Phage_GP20 PF06810.11 EKX32626.1 - 0.51 10.1 15.5 1 9.2 0.8 3.6 2 1 1 3 3 3 0 Phage minor structural protein GP20 DUF148 PF02520.17 EKX32626.1 - 3.1 8.0 17.1 0.033 14.3 3.2 3.8 3 2 1 4 4 4 0 Domain of unknown function DUF148 Spc7 PF08317.11 EKX32626.1 - 3.3 6.5 47.1 5.3 5.8 2.4 3.3 1 1 1 3 3 3 0 Spc7 kinetochore protein Rota_NSP4 PF01452.16 EKX32626.1 - 3.6 7.2 7.4 2.9 7.5 4.8 2.1 1 1 1 2 2 2 0 Rotavirus non structural protein Paf1 PF03985.13 EKX32627.1 - 0.00069 18.7 7.8 0.00083 18.5 7.8 1.2 1 0 0 1 1 1 1 Paf1 Atrophin-1 PF03154.15 EKX32627.1 - 1.9 6.7 12.8 2.7 6.2 12.8 1.1 1 0 0 1 1 1 0 Atrophin-1 family Trypan_PARP PF05887.11 EKX32627.1 - 4 7.4 5.5 7 6.6 5.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ank_2 PF12796.7 EKX32629.1 - 1e-39 135.0 5.8 4.7e-16 59.2 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX32629.1 - 4.2e-31 106.9 0.7 1e-09 38.7 0.0 4.3 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EKX32629.1 - 9.3e-28 95.4 9.5 6.6e-05 23.2 0.2 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 EKX32629.1 - 2.2e-26 89.0 0.6 0.00026 21.2 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EKX32629.1 - 6.5e-26 90.1 5.7 5.4e-06 26.6 0.1 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) TFIIS_C PF01096.18 EKX32631.1 - 2e-17 62.7 4.1 2.3e-17 62.5 4.1 1.1 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Baculo_LEF5_C PF11792.8 EKX32631.1 - 0.03 14.0 0.1 0.03 14.0 0.1 1.7 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain ADK_lid PF05191.14 EKX32631.1 - 0.032 14.2 2.1 0.1 12.6 0.2 2.0 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-ribbon_3 PF13248.6 EKX32631.1 - 0.04 13.3 1.0 5.2 6.6 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain UPF0547 PF10571.9 EKX32631.1 - 0.049 13.7 5.9 0.86 9.7 0.7 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Rubredoxin_2 PF18073.1 EKX32631.1 - 0.061 13.0 5.1 1 9.1 0.5 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain DUF2387 PF09526.10 EKX32631.1 - 0.096 12.8 4.4 0.55 10.4 3.1 2.0 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) DUF4379 PF14311.6 EKX32631.1 - 0.13 12.6 4.1 2.1 8.8 2.1 2.1 1 1 1 2 2 2 0 Probable Zinc-ribbon domain zf-RRN7 PF11781.8 EKX32631.1 - 0.17 11.6 6.1 16 5.3 6.1 2.8 1 1 0 1 1 1 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zn-ribbon_14 PF16503.5 EKX32631.1 - 0.32 10.5 3.7 8.9 5.9 0.1 2.3 2 0 0 2 2 2 0 Zinc-ribbon Ribosomal_L37e PF01907.19 EKX32631.1 - 0.99 9.6 7.7 6.3 7.0 0.3 2.2 1 1 1 2 2 2 0 Ribosomal protein L37e IQ PF00612.27 EKX32632.1 - 0.008 15.9 1.0 0.079 12.8 0.2 2.7 2 0 0 2 2 2 1 IQ calmodulin-binding motif Cwf_Cwc_15 PF04889.12 EKX32632.1 - 0.11 12.2 18.6 0.26 11.0 18.6 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 EKX32632.1 - 0.45 9.8 22.2 0.87 8.8 22.2 1.4 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 EKX32632.1 - 1.3 9.2 18.6 3.6 7.8 18.6 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Pkinase PF00069.25 EKX32633.1 - 3.8e-07 29.7 0.1 6.3e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain SSrecog PF03531.14 EKX32634.1 - 0.02 14.8 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 Structure-specific recognition protein (SSRP1) XG_FTase PF03254.13 EKX32635.1 - 1.6e-08 33.6 0.2 4.4e-06 25.6 0.0 2.0 2 0 0 2 2 2 2 Xyloglucan fucosyltransferase C2 PF00168.30 EKX32636.1 - 8.1e-20 71.0 0.0 8.7e-20 70.9 0.0 1.0 1 0 0 1 1 1 1 C2 domain LBP_C PF17386.2 EKX32636.1 - 0.013 15.4 0.1 0.025 14.5 0.1 1.4 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase C-terminal domain WD40 PF00400.32 EKX32637.1 - 1.2e-13 51.3 12.5 6.8e-05 23.6 0.2 8.2 9 0 0 9 9 9 4 WD domain, G-beta repeat HELP PF03451.14 EKX32637.1 - 2.8e-07 30.3 0.0 4.8e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 HELP motif ANAPC4_WD40 PF12894.7 EKX32637.1 - 8.6e-07 29.2 0.6 0.39 11.1 0.0 4.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EKX32637.1 - 0.046 13.0 1.7 1.3 8.3 0.0 2.9 3 0 0 3 3 3 0 WD40-like domain DUF3942 PF13078.6 EKX32637.1 - 0.083 13.2 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3942) SKA2 PF16740.5 EKX32638.1 - 0.05 13.4 0.6 0.21 11.4 0.6 2.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 NPR1_interact PF15699.5 EKX32638.1 - 0.21 12.2 3.4 0.2 12.3 0.6 2.2 1 1 1 2 2 2 0 NPR1 interacting Nop PF01798.18 EKX32639.1 - 0.096 12.1 1.1 6.1 6.3 0.0 2.1 1 1 1 2 2 2 0 snoRNA binding domain, fibrillarin Myb_DNA-bind_4 PF13837.6 EKX32640.1 - 0.0021 18.4 1.4 0.015 15.6 0.6 2.5 2 1 0 2 2 2 1 Myb/SANT-like DNA-binding domain Tex_N PF09371.10 EKX32640.1 - 0.14 11.8 0.1 0.35 10.5 0.0 1.7 1 1 0 1 1 1 0 Tex-like protein N-terminal domain Lyase_N PF09092.11 EKX32643.1 - 0.057 13.3 0.3 0.085 12.7 0.3 1.3 1 0 0 1 1 1 0 Lyase, N terminal CCDC-167 PF15188.6 EKX32643.1 - 8.5 6.8 6.4 14 6.1 3.0 2.3 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 DnaJ PF00226.31 EKX32644.1 - 6.9e-26 90.2 2.2 7.7e-26 90.0 2.2 1.0 1 0 0 1 1 1 1 DnaJ domain DUF884 PF05959.11 EKX32644.1 - 0.1 12.2 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF884) RelA_SpoT PF04607.17 EKX32645.1 - 0.0022 18.3 0.1 0.0061 16.8 0.1 1.7 1 1 0 1 1 1 1 Region found in RelA / SpoT proteins Glyco_transf_54 PF04666.13 EKX32646.1 - 0.0067 15.3 0.1 0.019 13.9 0.0 1.7 1 1 1 2 2 2 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region UMP1 PF05348.11 EKX32647.1 - 7.3e-18 64.9 0.4 8.8e-18 64.7 0.4 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Spt20 PF12090.8 EKX32648.1 - 7.1 6.2 12.6 20 4.7 12.6 1.8 1 0 0 1 1 1 0 Spt20 family Collagen PF01391.18 EKX32650.1 - 7e-20 70.5 74.2 1e-09 38.0 35.7 2.9 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Lectin_C PF00059.21 EKX32650.1 - 1e-09 39.1 4.4 1.6e-09 38.4 4.4 1.3 1 0 0 1 1 1 1 Lectin C-type domain DUF3376 PF11856.8 EKX32651.1 - 0.0064 15.5 0.1 0.0064 15.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3376) DUF688 PF05097.12 EKX32651.1 - 0.01 15.0 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF688) OpuAC PF04069.12 EKX32651.1 - 0.11 12.0 0.0 0.13 11.8 0.0 1.0 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system TFIID_30kDa PF03540.13 EKX32652.1 - 3.3e-24 84.6 0.1 5.4e-24 83.9 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit EF-hand_14 PF17959.1 EKX32652.1 - 0.0058 16.9 0.5 0.62 10.4 0.1 2.9 1 1 2 3 3 3 1 EF-hand domain TAF4 PF05236.14 EKX32652.1 - 0.016 15.0 0.2 0.019 14.7 0.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DSPn PF14671.6 EKX32653.1 - 9.4e-27 94.2 0.0 2.1e-25 89.8 0.1 2.2 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EKX32653.1 - 2e-12 47.0 0.0 4.6e-12 45.9 0.0 1.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX32653.1 - 0.0052 16.4 0.2 0.011 15.3 0.2 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX32653.1 - 0.0067 16.6 0.0 0.0097 16.0 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Sacchrp_dh_NADP PF03435.18 EKX32654.1 - 6.4e-11 42.6 0.0 9.9e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EKX32654.1 - 7.4e-05 22.3 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EKX32654.1 - 0.00022 21.2 0.1 0.00039 20.4 0.1 1.4 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 EKX32654.1 - 0.01 16.4 0.2 0.02 15.5 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GDP_Man_Dehyd PF16363.5 EKX32654.1 - 0.026 13.9 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EKX32654.1 - 0.13 11.8 0.8 0.23 11.0 0.3 1.7 2 0 0 2 2 2 0 NmrA-like family Shikimate_DH PF01488.20 EKX32654.1 - 0.15 12.1 0.2 0.28 11.3 0.2 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DMAP1_like PF17024.5 EKX32656.1 - 0.04 14.0 0.2 2.2 8.4 0.0 2.9 2 2 1 3 3 3 0 Putative DMAP1-like Alpha_adaptin_C PF02296.16 EKX32656.1 - 0.053 13.7 8.7 0.43 10.8 0.7 4.2 1 1 4 5 5 5 0 Alpha adaptin AP2, C-terminal domain GA PF01468.17 EKX32656.1 - 0.28 11.5 8.1 10 6.5 1.9 4.6 4 1 1 5 5 5 0 GA module VCBS PF13517.6 EKX32657.1 - 5.7e-17 62.1 19.2 3.1e-07 30.9 1.2 7.3 7 1 1 8 8 7 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EKX32657.1 - 4.1e-14 52.4 17.3 0.008 16.3 0.2 6.9 6 0 0 6 6 6 4 FG-GAP repeat EF-hand_5 PF13202.6 EKX32657.1 - 4.5e-08 32.2 23.9 0.0042 16.5 0.0 7.8 8 0 0 8 8 8 3 EF hand EF-hand_7 PF13499.6 EKX32657.1 - 5.5e-07 29.9 20.1 0.0032 17.9 5.2 4.9 5 0 0 5 5 4 3 EF-hand domain pair EF-hand_1 PF00036.32 EKX32657.1 - 1.6e-05 24.1 26.4 0.0048 16.3 0.0 8.3 9 0 0 9 9 9 3 EF hand PQQ_2 PF13360.6 EKX32657.1 - 0.0005 19.7 0.8 0.0022 17.6 0.9 2.0 1 1 1 2 2 2 2 PQQ-like domain EF-hand_8 PF13833.6 EKX32657.1 - 0.0008 19.2 5.9 1.1 9.2 0.1 4.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EKX32657.1 - 0.0011 18.8 29.0 0.024 14.6 0.0 7.3 10 0 0 10 10 8 3 EF-hand domain PQQ_3 PF13570.6 EKX32657.1 - 0.0014 19.0 5.7 3.9 8.1 0.5 5.1 4 0 0 4 4 4 1 PQQ-like domain Ins134_P3_kin_N PF17927.1 EKX32657.1 - 0.095 13.1 0.2 0.25 11.7 0.2 1.7 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain Dockerin_1 PF00404.18 EKX32657.1 - 0.14 12.3 8.3 36 4.7 0.3 6.0 6 0 0 6 6 6 0 Dockerin type I domain ANTAR PF03861.14 EKX32657.1 - 0.17 11.8 0.0 0.47 10.3 0.0 1.7 1 0 0 1 1 1 0 ANTAR domain EF-hand_10 PF14788.6 EKX32657.1 - 0.63 9.9 5.1 47 3.9 0.1 4.2 3 1 1 4 4 4 0 EF hand Itfg2 PF15907.5 EKX32657.1 - 0.86 8.6 8.4 3.4 6.6 0.1 4.5 3 1 2 5 5 5 0 Integrin-alpha FG-GAP repeat-containing protein 2 SPARC_Ca_bdg PF10591.9 EKX32657.1 - 1.9 8.8 6.2 76 3.7 1.3 3.4 1 1 2 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Met_gamma_lyase PF06838.11 EKX32658.1 - 5.1e-169 562.1 0.0 5.9e-169 561.9 0.0 1.0 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.21 EKX32658.1 - 0.00027 20.2 0.0 0.27 10.4 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EKX32658.1 - 0.00091 17.9 0.0 0.2 10.1 0.0 2.1 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme PDZ_6 PF17820.1 EKX32658.1 - 0.13 12.1 0.0 0.92 9.4 0.0 2.3 2 0 0 2 2 2 0 PDZ domain Peptidase_A22B PF04258.13 EKX32659.1 - 3.6e-44 151.4 2.8 3.6e-44 151.4 2.8 2.1 2 0 0 2 2 2 1 Signal peptide peptidase PA PF02225.22 EKX32659.1 - 4.1e-06 26.7 0.0 1.7e-05 24.7 0.0 2.2 1 1 0 1 1 1 1 PA domain DUF2207 PF09972.9 EKX32659.1 - 0.04 12.7 0.0 0.43 9.3 0.0 2.2 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Helicase_C PF00271.31 EKX32660.1 - 1.1e-08 35.4 0.1 2.6e-07 30.9 0.1 2.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EKX32660.1 - 9.9e-07 28.7 0.3 5.4e-05 23.0 0.3 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase HHH_5 PF14520.6 EKX32660.1 - 2.7e-05 24.7 0.4 0.00025 21.6 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 EKX32660.1 - 0.042 13.7 0.0 0.23 11.3 0.0 2.3 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda AAA_22 PF13401.6 EKX32660.1 - 0.056 13.7 0.3 0.24 11.7 0.0 2.3 3 0 0 3 3 3 0 AAA domain ResIII PF04851.15 EKX32660.1 - 0.062 13.3 0.3 0.24 11.4 0.1 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RCC1 PF00415.18 EKX32661.1 - 1.4e-42 144.0 9.4 1.7e-12 47.8 0.0 5.8 5 1 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX32661.1 - 1.9e-33 113.6 22.1 6.1e-10 38.6 1.5 4.4 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat DUF2383 PF09537.10 EKX32662.1 - 0.0019 18.5 0.1 0.0059 16.9 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2383) Exo_endo_phos PF03372.23 EKX32662.1 - 0.022 14.3 0.0 0.08 12.4 0.0 1.9 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Glyco_hydro_36 PF17167.4 EKX32662.1 - 0.051 12.3 0.0 0.087 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain Exo_endo_phos_2 PF14529.6 EKX32662.1 - 0.13 12.1 0.2 0.42 10.5 0.1 2.0 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase Peptidase_M16_C PF05193.21 EKX32663.1 - 0.017 15.1 0.0 0.039 14.0 0.0 1.6 1 1 0 1 1 1 0 Peptidase M16 inactive domain zf-CCCH PF00642.24 EKX32664.1 - 7e-19 67.3 10.3 1.7e-10 40.6 0.9 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EKX32664.1 - 6.1e-11 42.0 16.1 1.7e-06 27.9 1.9 2.9 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 EKX32664.1 - 1.9e-10 40.3 11.2 8.2e-06 25.5 1.0 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger oligo_HPY PF08352.12 EKX32664.1 - 0.001 19.5 4.9 0.082 13.4 0.4 2.2 2 0 0 2 2 2 2 Oligopeptide/dipeptide transporter, C-terminal region zf-CCCH_2 PF14608.6 EKX32664.1 - 0.0052 17.2 12.1 0.19 12.2 0.6 2.5 2 1 0 2 2 2 2 RNA-binding, Nab2-type zinc finger CRAM_rpt PF07016.11 EKX32664.1 - 0.14 12.0 1.4 4.4 7.2 0.1 2.9 3 0 0 3 3 3 0 Cysteine-rich acidic integral membrane protein precursor Ornatin PF02088.15 EKX32664.1 - 0.22 11.3 3.0 1.7 8.5 0.8 2.7 2 1 0 2 2 2 0 Ornatin Torus PF16131.5 EKX32664.1 - 0.33 11.6 9.2 1.4 9.7 2.9 2.1 1 1 1 2 2 2 0 Torus domain P2X_receptor PF00864.19 EKX32664.1 - 0.65 9.0 6.5 0.65 9.0 6.5 1.0 1 0 0 1 1 1 0 ATP P2X receptor Autophagy_N PF03986.13 EKX32665.1 - 0.082 12.8 2.0 0.095 12.6 2.0 1.1 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain C2 PF00168.30 EKX32666.1 - 0.00028 21.1 2.3 0.0011 19.2 0.0 2.6 2 0 0 2 2 2 1 C2 domain Menin PF05053.13 EKX32666.1 - 0.022 13.1 8.6 0.031 12.6 8.6 1.1 1 0 0 1 1 1 0 Menin RPOL_N PF14700.6 EKX32666.1 - 0.13 11.6 2.1 0.22 10.9 2.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal Spt20 PF12090.8 EKX32666.1 - 0.22 11.1 12.9 0.36 10.4 12.9 1.2 1 0 0 1 1 1 0 Spt20 family Amino_oxidase PF01593.24 EKX32667.1 - 3e-22 79.5 0.0 3.7e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase E3_binding PF02817.17 EKX32667.1 - 0.097 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 e3 binding domain Pyr_redox_2 PF07992.14 EKX32667.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PX PF00787.24 EKX32670.1 - 1.1e-12 48.0 0.1 1.6e-12 47.4 0.1 1.3 1 0 0 1 1 1 1 PX domain MFAP1 PF06991.11 EKX32671.1 - 0.012 15.5 2.1 0.012 15.5 2.1 1.5 1 1 1 2 2 2 0 Microfibril-associated/Pre-mRNA processing DivIC PF04977.15 EKX32672.1 - 3e-05 23.7 5.5 0.0097 15.7 0.9 2.1 2 0 0 2 2 2 2 Septum formation initiator DUF641 PF04859.12 EKX32672.1 - 0.0009 19.6 9.6 0.0021 18.4 9.6 1.5 1 1 0 1 1 1 1 Plant protein of unknown function (DUF641) Cnn_1N PF07989.11 EKX32672.1 - 0.0042 17.2 10.7 0.0058 16.8 10.7 1.2 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 Lzipper-MIP1 PF14389.6 EKX32672.1 - 0.0058 16.9 6.8 0.046 14.0 2.4 2.3 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 HIP1_clath_bdg PF16515.5 EKX32672.1 - 0.0073 16.9 10.0 0.017 15.7 10.0 1.6 1 1 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 HMMR_C PF15908.5 EKX32672.1 - 0.0079 16.5 7.4 0.19 12.0 0.4 2.1 1 1 1 2 2 2 2 Hyaluronan mediated motility receptor C-terminal Filament PF00038.21 EKX32672.1 - 0.014 15.0 8.4 0.034 13.7 8.3 1.5 1 1 0 1 1 1 0 Intermediate filament protein NuDC PF16273.5 EKX32672.1 - 0.02 15.4 3.0 0.02 15.4 3.0 1.9 2 0 0 2 2 2 0 Nuclear distribution C domain Spc7 PF08317.11 EKX32672.1 - 0.021 13.7 8.1 0.029 13.3 8.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Fez1 PF06818.15 EKX32672.1 - 0.023 15.1 7.3 0.031 14.7 7.3 1.1 1 0 0 1 1 1 0 Fez1 Phage_GPO PF05929.11 EKX32672.1 - 0.036 13.7 1.5 0.043 13.4 1.5 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF1664 PF07889.12 EKX32672.1 - 0.057 13.5 3.0 0.046 13.8 1.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fungal_TACC PF12709.7 EKX32672.1 - 0.06 13.8 10.0 0.75 10.3 4.3 2.2 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Mto2_bdg PF12808.7 EKX32672.1 - 0.061 13.6 10.9 0.15 12.4 1.5 2.9 2 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region RPW8 PF05659.11 EKX32672.1 - 0.073 12.8 4.4 0.13 12.0 1.3 1.9 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF4618 PF15397.6 EKX32672.1 - 0.073 12.5 10.5 0.49 9.8 3.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Uso1_p115_C PF04871.13 EKX32672.1 - 0.17 12.3 9.5 0.29 11.5 9.5 1.4 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3958 PF13125.6 EKX32672.1 - 0.19 12.0 10.7 0.36 11.1 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) G-gamma PF00631.22 EKX32672.1 - 0.21 11.6 9.0 1.1 9.3 0.3 2.8 2 1 1 3 3 3 0 GGL domain TSC22 PF01166.18 EKX32672.1 - 0.24 11.7 8.1 5 7.5 0.4 3.0 2 1 1 3 3 3 0 TSC-22/dip/bun family TPR_MLP1_2 PF07926.12 EKX32672.1 - 0.24 11.5 11.6 0.77 9.8 5.6 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein YabA PF06156.13 EKX32672.1 - 0.26 11.9 9.3 1.3 9.7 0.7 2.1 1 1 1 2 2 2 0 Initiation control protein YabA DUF4201 PF13870.6 EKX32672.1 - 0.32 10.7 11.7 1.7 8.4 4.7 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) DUF1640 PF07798.11 EKX32672.1 - 0.33 11.0 8.0 0.56 10.2 8.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) AAA_23 PF13476.6 EKX32672.1 - 0.33 11.4 6.8 0.41 11.1 6.8 1.1 1 0 0 1 1 1 0 AAA domain Phage_GP20 PF06810.11 EKX32672.1 - 0.37 10.6 10.8 2 8.2 10.8 1.8 1 1 0 1 1 1 0 Phage minor structural protein GP20 bZIP_1 PF00170.21 EKX32672.1 - 0.37 10.9 13.0 3.1 8.0 0.5 2.3 1 1 1 2 2 2 0 bZIP transcription factor Sec2p PF06428.11 EKX32672.1 - 0.39 10.7 12.7 1.7 8.6 12.7 1.9 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p CENP-H PF05837.12 EKX32672.1 - 0.39 11.1 7.8 0.98 9.9 7.8 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Swi5 PF07061.11 EKX32672.1 - 0.45 10.6 6.6 0.54 10.4 1.6 2.1 2 0 0 2 2 2 0 Swi5 DivIVA PF05103.13 EKX32672.1 - 0.56 10.3 8.8 2 8.5 3.9 2.1 1 1 1 2 2 2 0 DivIVA protein FlaC_arch PF05377.11 EKX32672.1 - 0.57 10.6 7.5 5.1 7.6 2.4 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) ATG16 PF08614.11 EKX32672.1 - 0.67 10.1 14.2 2.8 8.1 1.6 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Mis12 PF05859.12 EKX32672.1 - 0.72 9.9 8.2 4.9 7.2 8.2 1.9 1 1 0 1 1 1 0 Mis12 protein Seryl_tRNA_N PF02403.22 EKX32672.1 - 0.75 10.1 9.5 27 5.0 9.5 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Csm1_N PF18504.1 EKX32672.1 - 1.1 9.6 11.7 2.2 8.7 4.4 2.2 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF1068 PF06364.12 EKX32672.1 - 1.4 8.8 8.5 1.7 8.5 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) DUF4404 PF14357.6 EKX32672.1 - 3.5 8.3 8.1 1.2 9.8 1.7 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4404) Spc24 PF08286.11 EKX32672.1 - 3.6 7.9 11.6 7.4 6.9 1.5 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 ZapB PF06005.12 EKX32672.1 - 4.2 7.9 13.7 9.2e+02 0.4 13.7 2.3 1 1 0 1 1 1 0 Cell division protein ZapB p450 PF00067.22 EKX32674.1 - 3.8e-37 128.1 0.0 3e-23 82.3 0.0 3.0 2 1 0 2 2 2 2 Cytochrome P450 Adap_comp_sub PF00928.21 EKX32675.1 - 8.3e-73 245.0 0.0 1e-72 244.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EKX32675.1 - 3.9e-11 43.1 0.7 6.1e-11 42.4 0.7 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CLU PF13236.6 EKX32676.1 - 5.4e-31 108.1 0.0 1e-30 107.2 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria LRR_4 PF12799.7 EKX32676.1 - 2.1e-12 47.0 8.4 0.35 11.4 0.1 8.3 3 2 8 11 11 11 3 Leucine Rich repeats (2 copies) eIF3_p135 PF12807.7 EKX32676.1 - 6.2e-08 32.9 0.0 1.8e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 LRR_6 PF13516.6 EKX32676.1 - 8.1e-05 22.4 24.9 0.2 11.8 0.0 10.0 12 0 0 12 12 12 2 Leucine Rich repeat LRR_5 PF13306.6 EKX32676.1 - 0.0051 16.8 1.8 5.7 6.9 0.1 4.0 3 1 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EKX32676.1 - 0.013 16.0 14.0 15 6.6 0.1 9.0 10 0 0 10 10 10 0 Leucine Rich Repeat gpUL132 PF11359.8 EKX32676.1 - 0.031 13.8 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 TOM20_plant PF06552.12 EKX32676.1 - 0.039 13.7 0.0 0.11 12.3 0.0 1.7 1 1 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_14 PF13428.6 EKX32676.1 - 0.045 14.6 0.7 1.1 10.3 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat ACT PF01842.25 EKX32676.1 - 0.088 12.6 0.0 0.41 10.5 0.0 2.2 1 0 0 1 1 1 0 ACT domain Exog_C PF18026.1 EKX32676.1 - 0.15 12.2 0.7 0.41 10.8 0.7 1.7 1 0 0 1 1 1 0 Endo/exonuclease (EXOG) C-terminal domain Ins_allergen_rp PF06757.13 EKX32676.1 - 0.3 11.0 3.9 1.2 9.1 0.0 2.7 3 0 0 3 3 3 0 Insect allergen related repeat, nitrile-specifier detoxification FapA PF03961.13 EKX32676.1 - 0.65 8.5 6.5 7 5.1 5.9 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A WD40 PF00400.32 EKX32677.1 - 2.7e-47 157.7 12.7 5.8e-09 36.4 0.1 7.6 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX32677.1 - 4.6e-12 46.1 0.0 0.013 15.8 0.0 5.3 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 EKX32677.1 - 7.7e-12 44.5 1.0 1.8e-11 43.4 1.0 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like eIF2A PF08662.11 EKX32677.1 - 1.2e-05 25.3 0.0 0.061 13.2 0.0 3.8 2 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EKX32677.1 - 1.6e-05 24.1 0.0 0.61 9.0 0.0 4.0 3 1 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 EKX32677.1 - 0.0063 15.9 0.1 0.038 13.3 0.0 2.4 1 1 1 2 2 2 1 Neuroblastoma-amplified sequence, N terminal 4HBT_3 PF13622.6 EKX32677.1 - 0.033 14.5 0.0 0.068 13.4 0.0 1.5 1 0 0 1 1 1 0 Thioesterase-like superfamily WD40_like PF17005.5 EKX32677.1 - 0.055 12.8 0.0 29 3.9 0.0 2.9 1 1 2 3 3 3 0 WD40-like domain Nup160 PF11715.8 EKX32677.1 - 0.12 11.0 6.0 10 4.6 0.1 4.7 2 1 4 6 6 6 0 Nucleoporin Nup120/160 ApbA PF02558.16 EKX32678.1 - 1.1e-36 125.8 0.0 1.5e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EKX32678.1 - 2.2e-17 63.4 0.0 3.7e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal F420_oxidored PF03807.17 EKX32678.1 - 9.9e-06 26.1 0.0 2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 EKX32678.1 - 2.7e-05 24.2 0.0 7.6e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_10 PF13460.6 EKX32678.1 - 0.0014 18.5 0.0 0.0027 17.6 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Pyr_redox PF00070.27 EKX32678.1 - 0.0043 17.6 0.0 0.01 16.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EKX32678.1 - 0.018 15.5 0.0 0.034 14.6 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 EKX32678.1 - 0.021 14.4 0.1 0.044 13.4 0.1 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MgsA_C PF12002.8 EKX32678.1 - 0.034 14.1 0.1 0.087 12.8 0.1 1.6 2 0 0 2 2 2 0 MgsA AAA+ ATPase C terminal NAD_binding_8 PF13450.6 EKX32678.1 - 0.14 12.4 1.0 0.5 10.6 0.4 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF1676 PF07898.13 EKX32679.1 - 0.017 15.2 0.3 0.019 15.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) LON_substr_bdg PF02190.16 EKX32680.1 - 0.00019 21.4 0.1 0.0005 20.0 0.1 1.5 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain R3H PF01424.22 EKX32681.1 - 3.1e-05 23.9 0.0 0.00012 22.0 0.0 2.1 1 1 0 1 1 1 1 R3H domain CUB PF00431.20 EKX32682.1 - 1.9e-06 28.1 0.6 9.7e-06 25.9 0.0 2.7 2 0 0 2 2 2 1 CUB domain KH_1 PF00013.29 EKX32683.1 - 4.6e-14 52.0 0.6 1.4e-07 31.2 0.3 2.9 3 0 0 3 3 3 2 KH domain Agenet PF05641.12 EKX32683.1 - 9.7e-07 29.2 0.2 2e-05 25.0 0.2 2.7 3 0 0 3 3 3 1 Agenet domain KH_2 PF07650.17 EKX32683.1 - 3.4e-05 23.6 1.0 0.0068 16.2 0.3 2.6 2 0 0 2 2 2 1 KH domain KH_4 PF13083.6 EKX32683.1 - 7.5e-05 22.5 0.1 0.41 10.6 0.0 2.7 2 0 0 2 2 2 2 KH domain TFIIA PF03153.13 EKX32683.1 - 0.0028 17.7 27.8 0.005 16.9 27.8 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit AAT PF03417.16 EKX32683.1 - 0.032 13.9 4.7 0.06 13.0 4.7 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Spt20 PF12090.8 EKX32683.1 - 0.074 12.6 26.1 0.16 11.6 26.1 1.5 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 EKX32683.1 - 0.092 11.6 15.9 0.16 10.8 15.9 1.5 1 0 0 1 1 1 0 Androgen receptor Macoilin PF09726.9 EKX32683.1 - 0.37 9.3 18.8 0.51 8.8 18.8 1.1 1 0 0 1 1 1 0 Macoilin family SID-1_RNA_chan PF13965.6 EKX32683.1 - 0.43 8.9 3.2 0.6 8.4 3.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RR_TM4-6 PF06459.12 EKX32683.1 - 0.83 9.4 14.1 1.5 8.6 14.1 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.22 EKX32683.1 - 1.5 8.0 8.9 2.3 7.4 8.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4407 PF14362.6 EKX32683.1 - 1.6 8.0 11.6 2.6 7.3 11.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4820 PF16091.5 EKX32683.1 - 2.1 7.6 15.9 0.5 9.7 12.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4820) SelP_N PF04592.14 EKX32683.1 - 3.3 7.0 22.1 1 8.7 19.0 1.8 2 0 0 2 2 2 0 Selenoprotein P, N terminal region GREB1 PF15782.5 EKX32683.1 - 3.9 4.4 18.6 5 4.1 18.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer ALMT PF11744.8 EKX32683.1 - 5.1 5.8 12.5 8.1 5.1 12.5 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4404 PF14357.6 EKX32684.1 - 0.0046 17.6 18.1 0.5 11.0 2.7 4.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4404) Skp1 PF01466.19 EKX32684.1 - 0.0089 16.1 0.0 57 3.9 0.0 3.6 3 0 0 3 3 3 0 Skp1 family, dimerisation domain PCRF PF03462.18 EKX32684.1 - 0.018 14.9 4.3 5.4 6.8 0.6 3.5 3 0 0 3 3 3 0 PCRF domain Spc24 PF08286.11 EKX32684.1 - 0.057 13.7 17.2 60 3.9 0.0 5.7 5 0 0 5 5 5 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.11 EKX32684.1 - 0.065 13.6 5.3 20 5.6 0.1 4.6 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.10 EKX32684.1 - 0.16 12.1 4.3 17 5.6 0.1 3.5 4 0 0 4 4 3 0 Fibrinogen alpha/beta chain family Gp58 PF07902.11 EKX32684.1 - 0.39 8.9 10.9 1.9 6.7 1.9 2.4 2 0 0 2 2 2 0 gp58-like protein TolA_bind_tri PF16331.5 EKX32684.1 - 1.6 8.9 19.7 4 7.6 3.2 5.0 4 0 0 4 4 4 0 TolA binding protein trimerisation FOXP-CC PF16159.5 EKX32684.1 - 2.7 8.7 7.0 38 5.0 0.8 3.5 2 0 0 2 2 2 0 FOXP coiled-coil domain HIP1_clath_bdg PF16515.5 EKX32684.1 - 4.1 8.1 19.9 2.2 8.9 0.5 5.7 6 0 0 6 6 6 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4615 PF15393.6 EKX32684.1 - 4.9 7.7 12.8 18 5.9 2.6 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4615) REJ PF02010.15 EKX32685.1 - 6.3e-18 64.8 0.1 1.2e-12 47.4 0.0 3.8 4 0 0 4 4 4 2 REJ domain GTA_holin_3TM PF11351.8 EKX32686.1 - 0.37 11.3 2.0 0.59 10.7 2.0 1.3 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release Tox-ODYAM1 PF15642.6 EKX32686.1 - 0.99 8.3 4.1 1.2 8.0 4.1 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Alanine_zipper PF11839.8 EKX32688.1 - 0.0042 17.4 9.4 0.0042 17.4 9.4 2.2 2 0 0 2 2 2 1 Alanine-zipper, major outer membrane lipoprotein ZapB PF06005.12 EKX32688.1 - 1.9 9.0 15.4 0.2 12.1 6.3 2.2 2 0 0 2 2 2 0 Cell division protein ZapB Apolipoprotein PF01442.18 EKX32689.1 - 0.023 14.6 30.6 0.4 10.5 30.6 2.1 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain PCC_BT PF18140.1 EKX32689.1 - 0.035 14.5 1.7 0.042 14.2 0.6 1.7 2 0 0 2 2 2 0 Propionyl-coenzyme A carboxylase BT domain Flagellin_N PF00669.20 EKX32689.1 - 0.064 13.4 2.0 0.18 11.9 2.0 1.7 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region Androgen_recep PF02166.16 EKX32689.1 - 0.11 11.3 0.9 0.14 10.9 0.9 1.2 1 0 0 1 1 1 0 Androgen receptor OmpH PF03938.14 EKX32689.1 - 1.2 9.4 25.7 0.75 10.1 19.4 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF3332 PF11810.8 EKX32689.1 - 5 6.8 10.2 0.66 9.6 6.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3332) KH_4 PF13083.6 EKX32689.1 - 8.3 6.4 9.5 28 4.7 2.2 2.8 1 1 0 2 2 2 0 KH domain cNMP_binding PF00027.29 EKX32690.1 - 0.0069 16.4 0.3 0.1 12.7 0.0 3.1 4 0 0 4 4 4 1 Cyclic nucleotide-binding domain PH_4 PF15404.6 EKX32690.1 - 0.066 13.0 0.9 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain PP2C PF00481.21 EKX32691.1 - 1.4e-46 159.2 0.0 1.6e-46 159.0 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EKX32691.1 - 2.3e-05 24.1 0.0 4.3e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C 3HCDH_N PF02737.18 EKX32692.1 - 1.7e-56 191.0 1.6 2.2e-56 190.6 0.6 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 EKX32692.1 - 1.4e-22 80.3 0.2 2.8e-22 79.3 0.2 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EKX32692.1 - 7e-14 52.1 0.0 1.1e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 EKX32692.1 - 1.1e-13 51.6 0.0 3.8e-13 49.8 0.1 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EKX32692.1 - 0.085 13.0 2.0 0.19 11.9 0.8 2.3 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 EKX32692.1 - 0.092 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 EKX32692.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH PF00725.22 EKX32693.1 - 0.095 13.3 0.0 0.12 13.0 0.0 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain MoaC PF01967.21 EKX32694.1 - 7.5e-49 165.3 1.4 8.9e-49 165.1 1.4 1.1 1 0 0 1 1 1 1 MoaC family Ank_4 PF13637.6 EKX32695.1 - 2.3e-07 31.2 0.1 0.0034 17.9 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX32695.1 - 2.9e-06 27.8 0.0 3.8e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX32695.1 - 2.3e-05 24.6 0.0 4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX32695.1 - 3.8e-05 23.8 0.0 0.0054 17.1 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EKX32695.1 - 0.00087 19.6 0.0 0.018 15.5 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeat MtN3_slv PF03083.16 EKX32696.1 - 3.9e-33 113.4 9.1 8.5e-17 61.0 0.5 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PQ-loop PF04193.14 EKX32696.1 - 0.025 14.4 7.3 2.1 8.2 0.2 4.1 3 1 1 4 4 4 0 PQ loop repeat LAB_N PF07578.11 EKX32696.1 - 0.14 12.3 0.3 0.14 12.3 0.3 2.7 1 1 2 3 3 3 0 Lipid A Biosynthesis N-terminal domain DUF4149 PF13664.6 EKX32696.1 - 9.8 6.6 11.3 5.9 7.3 0.6 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) MFS_1 PF07690.16 EKX32699.1 - 1.4e-25 89.9 28.1 1.4e-25 89.9 28.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EKX32699.1 - 9e-09 34.7 1.9 9e-09 34.7 1.9 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter UPF0259 PF06790.11 EKX32699.1 - 0.024 14.4 0.5 0.054 13.3 0.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0259) Mito_carr PF00153.27 EKX32700.1 - 7.1e-06 25.8 0.4 7.1e-06 25.8 0.4 2.9 3 0 0 3 3 3 1 Mitochondrial carrier protein SET PF00856.28 EKX32701.1 - 1.7e-08 35.0 0.0 2.1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 SET domain EAP30 PF04157.16 EKX32702.1 - 1.6e-07 30.9 1.9 3.1e-06 26.7 0.2 2.1 1 1 1 2 2 2 2 EAP30/Vps36 family Nsp1 PF11501.8 EKX32702.1 - 0.037 14.1 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 Non structural protein Nsp1 Tryp_alpha_amyl PF00234.22 EKX32702.1 - 0.04 14.3 0.1 0.07 13.6 0.1 1.5 1 0 0 1 1 1 0 Protease inhibitor/seed storage/LTP family Terminase_4 PF05119.12 EKX32702.1 - 0.084 13.3 0.2 0.15 12.5 0.2 1.4 1 0 0 1 1 1 0 Phage terminase, small subunit P4Ha_N PF08336.11 EKX32703.1 - 0.18 11.9 3.6 1.9 8.5 3.4 2.1 1 1 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region HIP1_clath_bdg PF16515.5 EKX32703.1 - 5.9 7.6 13.3 0.86 10.3 4.9 2.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 RCC1_2 PF13540.6 EKX32704.1 - 5e-36 121.8 30.9 1.5e-09 37.4 0.1 7.1 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EKX32704.1 - 0.00026 21.5 34.2 1.5 9.5 0.2 8.7 7 3 2 9 9 9 4 Regulator of chromosome condensation (RCC1) repeat WAPL PF07814.13 EKX32705.1 - 1.4e-39 136.0 8.3 2.4e-39 135.2 8.3 1.4 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin UNC45-central PF11701.8 EKX32705.1 - 0.0056 16.6 2.7 0.0083 16.1 1.1 2.1 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central Wap1 PF16997.5 EKX32705.1 - 0.041 13.0 0.0 0.09 11.9 0.0 1.5 1 0 0 1 1 1 0 Wap1 domain PH PF00169.29 EKX32706.1 - 1.4e-11 44.8 0.0 1e-06 29.2 0.0 2.5 2 0 0 2 2 2 2 PH domain PH_8 PF15409.6 EKX32706.1 - 1.2e-05 25.5 0.0 3.4e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain START PF01852.19 EKX32706.1 - 0.0017 17.8 0.0 0.036 13.5 0.0 2.4 1 1 0 1 1 1 1 START domain PH_11 PF15413.6 EKX32706.1 - 0.028 14.9 0.1 0.61 10.5 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain PH_3 PF14593.6 EKX32706.1 - 0.1 12.7 0.0 0.44 10.7 0.0 1.9 2 0 0 2 2 2 0 PH domain Pro_isomerase PF00160.21 EKX32707.1 - 2.9e-50 170.6 0.1 3.3e-50 170.4 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNHCP PF12647.7 EKX32708.1 - 0.17 11.9 0.2 7.5 6.6 0.0 2.5 2 0 0 2 2 2 0 RNHCP domain RCC1_2 PF13540.6 EKX32709.1 - 1.1e-12 47.4 13.7 4.7e-07 29.4 0.2 3.7 3 1 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EKX32709.1 - 0.0026 18.4 13.7 4.2 8.1 0.4 5.2 4 1 1 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat DDHD PF02862.17 EKX32711.1 - 6.7e-06 26.4 3.1 7.8e-06 26.2 3.1 1.2 1 0 0 1 1 1 1 DDHD domain TFIIA PF03153.13 EKX32711.1 - 0.00016 21.8 38.5 0.00021 21.4 38.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit NPR3 PF03666.13 EKX32711.1 - 0.00078 18.3 13.5 0.0011 17.8 13.5 1.2 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 SpoIIP PF07454.11 EKX32711.1 - 0.00085 18.9 13.2 0.0012 18.4 13.2 1.2 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) CCSAP PF15748.5 EKX32711.1 - 0.001 19.3 16.3 0.0013 19.0 16.3 1.1 1 0 0 1 1 1 1 Centriole, cilia and spindle-associated GREB1 PF15782.5 EKX32711.1 - 0.0011 16.2 11.1 0.0011 16.2 11.1 1.0 1 0 0 1 1 1 1 Gene regulated by oestrogen in breast cancer DUF5308 PF17233.2 EKX32711.1 - 0.0016 18.7 8.0 0.0033 17.7 8.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5308) EPL1 PF10513.9 EKX32711.1 - 0.0019 18.6 13.5 0.0029 18.0 13.5 1.3 1 0 0 1 1 1 1 Enhancer of polycomb-like Velvet PF11754.8 EKX32711.1 - 0.0028 17.6 16.0 0.0038 17.2 16.0 1.1 1 0 0 1 1 1 1 Velvet factor Presenilin PF01080.17 EKX32711.1 - 0.0032 16.3 21.6 0.0042 15.9 21.6 1.1 1 0 0 1 1 1 1 Presenilin Lin-8 PF03353.15 EKX32711.1 - 0.0044 16.6 17.9 0.0071 16.0 17.9 1.3 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist PAT1 PF09770.9 EKX32711.1 - 0.012 13.9 28.0 0.015 13.7 28.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3295 PF11702.8 EKX32711.1 - 0.025 14.0 17.0 0.033 13.6 17.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Pex14_N PF04695.13 EKX32711.1 - 0.031 15.0 32.2 0.052 14.2 32.2 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CPSF100_C PF13299.6 EKX32711.1 - 0.044 14.0 12.6 0.074 13.2 12.6 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal ABC2_membrane_2 PF12679.7 EKX32711.1 - 0.044 13.1 0.3 0.052 12.8 0.3 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein AF-4 PF05110.13 EKX32711.1 - 0.085 10.9 22.0 0.1 10.7 22.0 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Zip PF02535.22 EKX32711.1 - 0.096 11.9 8.5 0.13 11.4 8.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ndc1_Nup PF09531.10 EKX32711.1 - 0.11 11.2 13.2 0.12 11.0 13.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pkinase_fungal PF17667.1 EKX32711.1 - 0.13 11.0 7.8 0.17 10.6 7.8 1.1 1 0 0 1 1 1 0 Fungal protein kinase Otopetrin PF03189.13 EKX32711.1 - 0.19 10.5 6.3 0.23 10.3 6.3 1.1 1 0 0 1 1 1 0 Otopetrin FAM60A PF15396.6 EKX32711.1 - 0.21 11.6 15.1 0.32 11.0 15.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Dsh_C PF12316.8 EKX32711.1 - 0.23 11.8 11.5 0.33 11.3 11.5 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal SMYLE_N PF18615.1 EKX32711.1 - 0.23 11.0 13.0 0.29 10.6 13.0 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain MMR1 PF08505.10 EKX32711.1 - 0.24 11.7 21.4 0.33 11.2 21.4 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein GvpL_GvpF PF06386.11 EKX32711.1 - 0.25 11.3 10.6 0.79 9.6 9.5 2.1 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Apt1 PF10351.9 EKX32711.1 - 0.25 10.2 12.9 0.29 9.9 12.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CCDC53 PF10152.9 EKX32711.1 - 0.33 11.4 19.7 0.53 10.7 19.7 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Endostatin PF06482.11 EKX32711.1 - 0.39 10.1 17.5 0.56 9.6 17.5 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin CDC45 PF02724.14 EKX32711.1 - 0.57 8.4 21.9 0.81 7.9 21.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Cellulose_synt PF03552.14 EKX32711.1 - 0.57 8.6 7.2 0.74 8.2 7.2 1.1 1 0 0 1 1 1 0 Cellulose synthase SAPS PF04499.15 EKX32711.1 - 0.62 8.8 14.9 0.8 8.4 14.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4228 PF14009.6 EKX32711.1 - 0.62 10.4 8.9 1.1 9.7 8.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Neur_chan_memb PF02932.16 EKX32711.1 - 0.77 9.8 15.1 1.2 9.1 15.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PepSY_TM PF03929.16 EKX32711.1 - 0.99 9.0 7.8 1.5 8.4 7.8 1.3 1 0 0 1 1 1 0 PepSY-associated TM region Hydin_ADK PF17213.3 EKX32711.1 - 1.4 9.1 15.2 2.4 8.4 15.2 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain VIT1 PF01988.19 EKX32711.1 - 1.6 8.6 4.2 2.6 7.9 4.2 1.4 1 0 0 1 1 1 0 VIT family AIF_C PF14721.6 EKX32711.1 - 1.7 9.0 15.9 3.1 8.2 15.9 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Raftlin PF15250.6 EKX32711.1 - 2.3 6.9 17.4 3.8 6.1 17.4 1.3 1 0 0 1 1 1 0 Raftlin Tim54 PF11711.8 EKX32711.1 - 2.3 6.9 18.6 3.4 6.4 18.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 MCM_bind PF09739.9 EKX32711.1 - 2.7 6.3 19.9 4.1 5.7 19.9 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Plasmodium_Vir PF05795.11 EKX32711.1 - 2.8 7.3 9.3 3.4 7.0 9.3 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Ctr PF04145.15 EKX32711.1 - 3 8.4 10.6 5.2 7.7 10.6 1.5 1 0 0 1 1 1 0 Ctr copper transporter family Maf1 PF09174.10 EKX32711.1 - 3.4 7.8 9.4 5.9 7.0 9.4 1.4 1 0 0 1 1 1 0 Maf1 regulator DUF4820 PF16091.5 EKX32711.1 - 3.4 7.0 16.5 6.8 6.0 16.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF3292 PF11696.8 EKX32711.1 - 3.6 5.8 12.6 4.8 5.4 12.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Spore_coat_CotO PF14153.6 EKX32711.1 - 3.8 7.4 27.6 5.6 6.8 27.6 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF572 PF04502.13 EKX32711.1 - 4 7.0 21.3 5.4 6.5 21.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) MFMR_assoc PF16596.5 EKX32711.1 - 4.6 7.7 15.4 7.8 7.0 15.4 1.4 1 0 0 1 1 1 0 Disordered region downstream of MFMR DUF913 PF06025.12 EKX32711.1 - 5.6 5.8 16.0 8.1 5.3 16.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SLC12 PF03522.15 EKX32711.1 - 5.7 5.8 23.9 7.7 5.4 23.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 MDFI PF15316.6 EKX32711.1 - 5.9 6.9 14.1 9.6 6.3 14.1 1.3 1 0 0 1 1 1 0 MyoD family inhibitor Band_3_cyto PF07565.13 EKX32711.1 - 6 6.6 24.5 12 5.6 24.5 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Hamartin PF04388.12 EKX32711.1 - 6 5.4 19.8 7.3 5.1 19.8 1.1 1 0 0 1 1 1 0 Hamartin protein Smg8_Smg9 PF10220.9 EKX32711.1 - 6.6 4.9 19.3 8.5 4.5 19.3 1.1 1 0 0 1 1 1 0 Smg8_Smg9 Connexin PF00029.19 EKX32711.1 - 6.8 6.4 18.4 10 5.8 18.4 1.2 1 0 0 1 1 1 0 Connexin DUF2370 PF10176.9 EKX32711.1 - 7.2 6.2 11.2 11 5.6 11.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) UPF0565 PF10561.9 EKX32711.1 - 8.1 5.5 11.1 12 5.0 11.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 FAM91_C PF14648.6 EKX32711.1 - 8.3 5.1 11.3 12 4.6 11.3 1.2 1 0 0 1 1 1 0 FAM91 C-terminus OATP PF03137.20 EKX32711.1 - 9.6 4.4 10.1 13 3.9 10.1 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family WD40 PF00400.32 EKX32714.1 - 6.9e-38 128.0 19.7 2.1e-08 34.7 1.2 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX32714.1 - 1.7e-20 73.1 0.3 5.6e-07 29.8 0.0 4.0 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 EKX32714.1 - 2.4e-05 22.9 0.1 0.12 10.6 0.0 2.8 2 2 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 EKX32714.1 - 8.6e-05 21.6 0.1 0.96 8.3 0.1 3.7 1 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EKX32714.1 - 0.015 14.7 0.0 6.9 5.9 0.0 3.1 3 0 0 3 3 3 0 WD40-like domain DUF2415 PF10313.9 EKX32714.1 - 0.039 13.9 5.5 7.5 6.6 0.0 3.8 4 0 0 4 4 4 0 Uncharacterised protein domain (DUF2415) eIF2A PF08662.11 EKX32714.1 - 0.045 13.6 0.0 0.16 11.8 0.0 1.8 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A CPSF_A PF03178.15 EKX32714.1 - 0.21 10.9 0.0 0.77 9.0 0.0 2.0 1 1 1 2 2 2 0 CPSF A subunit region SH3_4 PF06347.13 EKX32714.1 - 0.71 9.7 4.2 1.4 8.8 0.2 2.8 3 0 0 3 3 3 0 Bacterial SH3 domain HSP70 PF00012.20 EKX32715.1 - 3.2e-142 474.8 0.0 1.8e-141 472.3 0.0 2.0 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EKX32715.1 - 1.4e-06 27.4 0.0 2.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein HMG_box PF00505.19 EKX32716.1 - 6.9e-42 141.7 21.6 3.5e-21 75.4 2.7 2.8 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EKX32716.1 - 1.9e-25 89.2 32.3 2.5e-14 53.6 11.6 3.1 3 0 0 3 3 3 2 HMG-box domain SSrecog PF03531.14 EKX32716.1 - 8.5e-20 70.4 0.0 2.5e-19 69.0 0.0 1.9 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 EKX32716.1 - 2.4e-17 63.1 0.6 6.9e-17 61.6 0.2 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like POB3_N PF17292.2 EKX32716.1 - 3e-12 46.8 1.3 2.3e-09 37.5 0.0 3.1 2 1 1 3 3 3 2 POB3-like N-terminal PH domain CHDNT PF08073.12 EKX32716.1 - 0.0043 17.0 0.1 0.036 14.0 0.1 2.4 2 0 0 2 2 2 1 CHDNT (NUC034) domain Med30 PF11315.8 EKX32720.1 - 0.00027 21.2 1.2 0.0005 20.3 1.2 1.6 1 1 0 1 1 1 1 Mediator complex subunit 30 Spc7 PF08317.11 EKX32720.1 - 0.013 14.4 3.4 0.017 14.1 3.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Lectin_N PF03954.14 EKX32720.1 - 0.015 15.0 4.2 0.025 14.3 4.2 1.5 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain Seryl_tRNA_N PF02403.22 EKX32720.1 - 0.017 15.4 2.4 0.023 14.9 2.4 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Tropomyosin_1 PF12718.7 EKX32720.1 - 0.018 15.2 9.8 0.13 12.4 5.9 2.1 1 1 1 2 2 2 0 Tropomyosin like DUF4559 PF15112.6 EKX32720.1 - 0.024 14.3 1.4 0.031 14.0 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) STAT_alpha PF01017.20 EKX32720.1 - 0.042 13.8 3.8 0.61 10.0 3.8 2.0 1 1 0 1 1 1 0 STAT protein, all-alpha domain FapA PF03961.13 EKX32720.1 - 0.084 11.5 0.6 0.098 11.2 0.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Bacillus_HBL PF05791.11 EKX32720.1 - 0.22 11.3 2.8 2 8.2 1.6 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) XLF PF09302.11 EKX32720.1 - 0.32 11.1 4.7 3 8.0 4.7 1.9 1 1 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Sec2p PF06428.11 EKX32720.1 - 0.7 9.9 8.9 0.5 10.4 4.8 2.3 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Bestrophin PF01062.21 EKX32722.1 - 1.8e-25 89.9 1.8 3.8e-24 85.6 1.8 2.0 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel zf-C4 PF00105.18 EKX32723.1 - 0.29 11.6 1.0 0.67 10.5 1.0 1.6 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) TPR_8 PF13181.6 EKX32724.1 - 0.015 15.5 0.1 0.035 14.3 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.6 EKX32724.1 - 0.031 14.0 0.1 0.057 13.1 0.1 1.4 1 0 0 1 1 1 0 TPR repeat TPR_2 PF07719.17 EKX32724.1 - 0.076 13.2 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX32724.1 - 0.077 13.5 0.2 0.22 12.1 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX32724.1 - 0.16 12.9 0.1 0.36 11.8 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Kelch_4 PF13418.6 EKX32725.1 - 5e-32 109.7 2.8 3.2e-06 27.0 0.0 6.4 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 EKX32725.1 - 3e-31 107.1 2.0 1.8e-05 24.9 0.0 7.0 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EKX32725.1 - 7.3e-26 89.7 1.9 0.00024 21.0 0.2 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 EKX32725.1 - 4.8e-25 87.0 4.4 2.3e-07 30.9 0.0 6.6 5 1 1 6 6 6 3 Kelch motif Kelch_2 PF07646.15 EKX32725.1 - 1.2e-18 66.2 9.6 4.3e-05 23.3 0.1 6.0 6 0 0 6 6 6 5 Kelch motif DUF4110 PF13422.6 EKX32725.1 - 3.7e-12 46.2 0.4 3.7e-12 46.2 0.4 3.0 3 0 0 3 3 2 1 Domain of unknown function (DUF4110) Kelch_1 PF01344.25 EKX32725.1 - 1.5e-10 40.5 3.8 0.18 11.4 0.1 6.3 5 1 0 5 5 5 3 Kelch motif CDC45 PF02724.14 EKX32725.1 - 0.2 9.9 8.9 0.33 9.2 8.9 1.4 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EKX32725.1 - 0.55 8.4 15.4 0.87 7.7 15.4 1.3 1 0 0 1 1 1 0 Nop14-like family TEX19 PF15553.6 EKX32725.1 - 0.98 9.4 5.1 2.3 8.2 5.1 1.6 1 0 0 1 1 1 0 Testis-expressed protein 19 DNA_pol_phi PF04931.13 EKX32725.1 - 2.5 6.1 19.9 3.7 5.5 19.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi Hid1 PF12722.7 EKX32725.1 - 3.7 5.6 4.5 5.7 4.9 4.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TRAP_alpha PF03896.16 EKX32725.1 - 8.3 5.5 7.1 17 4.5 7.1 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit B9-C2 PF07162.11 EKX32726.1 - 4.1e-37 128.0 0.0 8.7e-37 126.9 0.0 1.6 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Ammonium_transp PF00909.21 EKX32727.1 - 4.3e-117 391.2 32.2 5.3e-117 390.9 32.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF846 PF05832.12 EKX32728.1 - 3.8e-55 185.7 11.0 4.7e-55 185.5 11.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Orthopox_A43R PF06517.11 EKX32728.1 - 0.045 13.5 0.3 0.079 12.8 0.3 1.3 1 0 0 1 1 1 0 Orthopoxvirus A43R protein He_PIG PF05345.12 EKX32729.1 - 0.00027 21.0 0.1 0.0017 18.5 0.0 2.3 3 0 0 3 3 3 1 Putative Ig domain HEAT_2 PF13646.6 EKX32729.1 - 0.0098 16.3 7.5 0.56 10.6 0.3 4.0 3 1 1 4 4 4 2 HEAT repeats F5_F8_type_C PF00754.25 EKX32729.1 - 0.13 12.4 0.1 0.34 11.0 0.1 1.7 1 0 0 1 1 1 0 F5/8 type C domain Connexin PF00029.19 EKX32730.1 - 0.29 10.9 12.8 0.36 10.6 12.8 1.2 1 0 0 1 1 1 0 Connexin DUF913 PF06025.12 EKX32730.1 - 0.44 9.5 13.0 0.52 9.2 13.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RNA_pol_Rpc4 PF05132.14 EKX32730.1 - 0.59 10.5 16.6 0.68 10.3 16.6 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Merozoite_SPAM PF07133.11 EKX32730.1 - 0.7 9.9 21.8 0.74 9.8 21.8 1.0 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Presenilin PF01080.17 EKX32730.1 - 1.8 7.2 20.7 1.8 7.3 20.7 1.0 1 0 0 1 1 1 0 Presenilin Gti1_Pac2 PF09729.9 EKX32730.1 - 2.1 8.4 14.6 2.6 8.1 14.6 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family TRAP_alpha PF03896.16 EKX32730.1 - 2.3 7.3 11.4 2.6 7.2 11.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4824 PF16106.5 EKX32730.1 - 3.6 6.8 16.0 5.2 6.3 16.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4824) RPOL_N PF14700.6 EKX32730.1 - 3.8 6.8 19.3 4.4 6.6 19.3 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal RR_TM4-6 PF06459.12 EKX32730.1 - 3.8 7.3 22.0 4.2 7.1 22.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CobT PF06213.12 EKX32730.1 - 4 6.7 28.2 4.8 6.5 28.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT XRN_M PF17846.1 EKX32730.1 - 5.4 5.8 14.2 5.4 5.9 14.2 1.0 1 0 0 1 1 1 0 Xrn1 helical domain Zip PF02535.22 EKX32730.1 - 5.7 6.1 17.7 5.9 6.0 17.7 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4820 PF16091.5 EKX32730.1 - 6.9 6.0 12.5 9.5 5.5 12.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) PTPRCAP PF15713.5 EKX32730.1 - 7.6 6.8 22.8 8 6.7 22.8 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated PH PF00169.29 EKX32731.1 - 4.2e-13 49.7 0.0 5.8e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 EKX32731.1 - 0.00018 21.8 0.0 0.00039 20.8 0.0 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 EKX32731.1 - 0.043 13.6 0.2 0.062 13.1 0.2 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain zf-CHC2 PF01807.20 EKX32731.1 - 0.048 13.5 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 CHC2 zinc finger PH_11 PF15413.6 EKX32731.1 - 0.076 13.4 1.3 0.5 10.8 0.3 2.3 2 1 0 2 2 2 0 Pleckstrin homology domain DAO PF01266.24 EKX32732.1 - 1.2e-50 173.1 0.8 1.8e-50 172.5 0.8 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EKX32732.1 - 0.00014 21.2 1.4 0.073 12.3 1.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EKX32732.1 - 0.0014 18.0 1.8 0.0021 17.4 0.8 1.6 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 EKX32732.1 - 0.0065 15.6 2.4 0.5 9.4 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox PF00070.27 EKX32732.1 - 0.015 15.8 1.7 0.076 13.6 0.3 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EKX32732.1 - 0.023 14.9 1.2 0.072 13.3 1.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 EKX32732.1 - 0.029 14.2 0.3 0.051 13.5 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EKX32732.1 - 0.071 12.8 0.2 0.17 11.5 0.2 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EKX32732.1 - 0.088 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.17 EKX32732.1 - 0.21 10.8 4.6 0.13 11.5 0.8 2.2 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 EKX32732.1 - 1 8.4 5.6 1.8 7.6 4.3 1.8 2 0 0 2 2 2 0 FAD binding domain Ribosomal_L12 PF00542.19 EKX32733.1 - 8.4e-20 70.9 9.1 8.8e-19 67.6 4.6 2.1 2 0 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EKX32733.1 - 0.0013 18.4 28.3 1.6 8.5 24.9 2.9 2 1 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain Ribosomal_60s PF00428.19 EKX32733.1 - 0.015 15.9 7.6 0.015 15.9 7.6 2.0 1 1 0 2 2 2 0 60s Acidic ribosomal protein TTL PF03133.15 EKX32734.1 - 2.3e-75 253.5 0.1 2.9e-75 253.1 0.1 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EKX32734.1 - 8.1e-09 35.1 0.1 8.4e-05 21.9 0.0 3.5 3 1 0 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EKX32734.1 - 5.2e-06 25.9 0.0 0.035 13.4 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EKX32734.1 - 0.0098 15.9 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 EKX32734.1 - 0.013 15.1 0.0 0.097 12.3 0.0 2.0 2 0 0 2 2 2 0 RimK-like ATP-grasp domain GSH-S_ATP PF02955.16 EKX32734.1 - 0.19 11.1 0.0 0.38 10.1 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain HEAT PF02985.22 EKX32735.1 - 5.4e-08 32.4 3.9 0.31 11.4 0.1 4.4 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.6 EKX32735.1 - 1.6e-05 25.2 3.4 0.0031 17.9 0.5 2.5 2 1 0 2 2 2 2 HEAT repeats HEAT_EZ PF13513.6 EKX32735.1 - 0.0054 17.2 3.0 25 5.5 0.0 3.8 3 1 1 4 4 4 2 HEAT-like repeat RTP1_C1 PF10363.9 EKX32735.1 - 0.013 15.7 0.0 0.12 12.6 0.0 2.1 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Ribosomal_L11_N PF03946.14 EKX32738.1 - 1.1e-26 92.4 0.1 2.1e-26 91.5 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EKX32738.1 - 1.6e-25 89.3 0.4 2.2e-25 88.9 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain PAT1 PF09770.9 EKX32739.1 - 0.058 11.7 9.0 0.25 9.6 0.2 3.5 3 1 0 3 3 3 0 Topoisomerase II-associated protein PAT1 Ank_4 PF13637.6 EKX32740.1 - 1.2e-17 64.0 0.1 8.3e-10 39.0 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX32740.1 - 1.2e-13 50.9 0.2 1.4e-13 50.8 0.2 1.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX32740.1 - 1.8e-12 47.1 0.7 2.9e-06 27.4 0.0 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EKX32740.1 - 4e-11 43.3 0.1 2.1e-08 34.6 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX32740.1 - 8e-11 41.2 0.2 1.5e-06 28.1 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat CRAL_TRIO PF00650.20 EKX32741.1 - 2e-34 118.6 0.0 4.3e-34 117.5 0.0 1.5 1 1 1 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EKX32741.1 - 1e-06 28.8 0.1 3.1e-06 27.3 0.1 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EKX32741.1 - 1.6e-06 28.3 0.0 3.4e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain SDA1 PF05285.12 EKX32743.1 - 3.5e-07 30.0 32.2 6.3e-07 29.1 32.2 1.4 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 EKX32743.1 - 6.9e-06 24.6 19.5 1.7e-05 23.4 19.5 1.6 1 0 0 1 1 1 1 CDC45-like protein Arm_2 PF04826.13 EKX32743.1 - 1.3e-05 24.8 0.8 0.92 8.9 0.0 4.1 3 1 1 4 4 4 2 Armadillo-like Caldesmon PF02029.15 EKX32743.1 - 0.00058 18.8 32.9 0.00099 18.0 32.9 1.3 1 0 0 1 1 1 1 Caldesmon BUD22 PF09073.10 EKX32743.1 - 0.00097 18.6 34.1 0.0023 17.3 34.1 1.6 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 EKX32743.1 - 0.0038 15.5 45.0 0.0059 14.9 45.0 1.2 1 0 0 1 1 1 1 Nop14-like family Mpp10 PF04006.12 EKX32743.1 - 0.013 13.9 42.9 0.021 13.3 42.9 1.2 1 0 0 1 1 1 0 Mpp10 protein CobT PF06213.12 EKX32743.1 - 0.025 14.0 40.3 0.06 12.7 40.3 1.6 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NPR3 PF03666.13 EKX32743.1 - 0.099 11.4 16.8 0.15 10.8 16.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PIP5K PF01504.18 EKX32743.1 - 0.15 11.2 2.8 0.29 10.3 2.8 1.6 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase Presenilin PF01080.17 EKX32743.1 - 0.29 9.8 22.3 0.45 9.2 22.3 1.2 1 0 0 1 1 1 0 Presenilin BIRC6 PF12356.8 EKX32743.1 - 0.35 10.3 5.8 0.87 9.0 5.8 1.6 1 0 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 DUF4045 PF13254.6 EKX32743.1 - 0.91 9.1 20.6 1.7 8.2 20.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) GAGA_bind PF06217.12 EKX32743.1 - 0.99 9.6 8.0 2.5 8.3 8.0 1.7 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2151 PF10221.9 EKX32743.1 - 1.8 7.0 18.1 3.3 6.2 18.1 1.3 1 0 0 1 1 1 0 Cell cycle and development regulator Zip PF02535.22 EKX32743.1 - 2 7.6 15.8 3.3 6.8 15.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PPP4R2 PF09184.11 EKX32743.1 - 2.1 7.8 45.2 3.7 7.1 45.2 1.3 1 0 0 1 1 1 0 PPP4R2 AAA_11 PF13086.6 EKX32743.1 - 3.6 7.3 20.3 14 5.4 20.3 2.0 1 0 0 1 1 1 0 AAA domain Raftlin PF15250.6 EKX32743.1 - 4.8 5.8 16.8 8.7 5.0 16.8 1.3 1 0 0 1 1 1 0 Raftlin Neur_chan_memb PF02932.16 EKX32743.1 - 7 6.6 11.8 17 5.4 11.8 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CENP-N PF05238.13 EKX32743.1 - 7.5 5.7 15.0 13 5.0 15.0 1.3 1 0 0 1 1 1 0 Kinetochore protein CHL4 like NARP1 PF12569.8 EKX32743.1 - 7.6 5.3 29.9 13 4.6 29.9 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Merozoite_SPAM PF07133.11 EKX32743.1 - 9.9 6.1 74.4 19 5.2 74.4 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) ABC_membrane PF00664.23 EKX32744.1 - 7.5e-20 71.7 0.3 7.5e-20 71.7 0.3 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 EKX32744.1 - 2e-19 70.5 0.0 1.5e-18 67.6 0.0 2.4 2 2 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EKX32744.1 - 0.00047 19.7 1.6 0.01 15.3 0.1 2.0 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 EKX32744.1 - 0.061 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_18 PF13238.6 EKX32744.1 - 0.12 12.9 0.0 0.39 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EKX32744.1 - 0.14 11.9 0.3 0.42 10.4 0.3 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EKX32744.1 - 0.24 11.6 1.3 1.9 8.8 1.3 2.3 1 1 0 1 1 1 0 AAA domain DUF2757 PF10955.8 EKX32745.1 - 0.17 12.1 0.2 0.17 12.1 0.2 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2757) Apolipoprotein PF01442.18 EKX32745.1 - 9.1 6.1 65.4 34 4.3 32.0 3.7 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Porin_3 PF01459.22 EKX32746.1 - 9.1e-21 74.5 2.6 1.1e-20 74.3 2.6 1.1 1 0 0 1 1 1 1 Eukaryotic porin Y_phosphatase2 PF03162.13 EKX32747.1 - 1.5e-53 180.8 0.0 1.9e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EKX32747.1 - 9.7e-08 32.3 0.0 2.1e-07 31.1 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EKX32747.1 - 0.0016 18.0 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EKX32747.1 - 0.027 14.3 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 EKX32747.1 - 0.047 13.4 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) LSM PF01423.22 EKX32748.1 - 2.4e-05 23.9 0.0 3.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain 4HBT_3 PF13622.6 EKX32749.1 - 0.0016 18.8 0.3 0.019 15.2 0.1 2.0 2 0 0 2 2 2 1 Thioesterase-like superfamily DUF287 PF03384.14 EKX32750.1 - 0.73 10.3 3.5 2.1 8.8 0.4 2.4 2 0 0 2 2 2 0 Drosophila protein of unknown function, DUF287 FAM184 PF15665.5 EKX32750.1 - 2.9 7.6 16.0 0.24 11.1 10.6 2.0 2 1 0 2 2 2 0 Family with sequence similarity 184, A and B ISG65-75 PF11727.8 EKX32750.1 - 4.1 6.6 11.9 0.29 10.3 6.5 1.7 2 0 0 2 2 2 0 Invariant surface glycoprotein Vps5 PF09325.10 EKX32750.1 - 5.3 6.5 13.6 0.1 12.1 1.2 2.6 3 0 0 3 3 3 0 Vps5 C terminal like MCU PF04678.13 EKX32750.1 - 5.4 7.1 6.8 1.7 8.7 1.9 2.1 1 1 1 2 2 2 0 Mitochondrial calcium uniporter V_ATPase_I PF01496.19 EKX32751.1 - 4.7e-230 765.8 0.0 3e-228 759.8 0.0 2.0 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF1688 PF07958.11 EKX32751.1 - 0.072 11.8 0.1 0.11 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1688) DUF615 PF04751.14 EKX32751.1 - 0.37 10.7 2.8 0.19 11.7 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF615) Caveolin PF01146.17 EKX32751.1 - 0.63 10.0 3.1 1.6 8.7 3.1 1.6 1 0 0 1 1 1 0 Caveolin ParA PF10609.9 EKX32752.1 - 3e-78 262.7 0.3 3e-78 262.7 0.3 2.7 1 1 1 2 2 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EKX32752.1 - 1.6e-10 41.1 0.0 9.3e-10 38.6 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 EKX32752.1 - 0.00025 20.4 0.4 0.00025 20.4 0.4 3.9 3 1 1 4 4 2 1 Anion-transporting ATPase AAA_31 PF13614.6 EKX32752.1 - 0.0014 18.5 0.0 0.0014 18.5 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_25 PF13481.6 EKX32752.1 - 0.0058 16.2 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain MipZ PF09140.11 EKX32752.1 - 0.0074 15.6 0.0 0.0074 15.6 0.0 2.1 2 0 0 2 2 2 1 ATPase MipZ AAA_26 PF13500.6 EKX32752.1 - 0.019 14.8 0.1 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EKX32752.1 - 0.035 14.0 0.1 0.035 14.0 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 EKX32752.1 - 0.089 12.7 0.6 0.18 11.7 0.6 1.5 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 EKX32752.1 - 0.12 12.4 0.1 0.12 12.4 0.1 2.1 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 EKX32752.1 - 0.16 12.3 0.1 0.25 11.7 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain DUF3450 PF11932.8 EKX32753.1 - 0.00034 20.0 11.7 0.00091 18.6 0.5 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) AAA_11 PF13086.6 EKX32753.1 - 0.00036 20.4 0.0 0.00036 20.4 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 EKX32753.1 - 0.0038 17.6 0.1 0.012 16.0 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 EKX32753.1 - 0.0047 16.5 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF948 PF06103.11 EKX32753.1 - 0.0058 16.9 1.7 0.0058 16.9 1.7 2.4 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) AAA_13 PF13166.6 EKX32753.1 - 0.0061 15.3 1.7 0.0061 15.3 1.7 2.5 1 1 2 3 3 3 1 AAA domain AAA_25 PF13481.6 EKX32753.1 - 0.011 15.4 0.1 0.037 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain BLOC1_2 PF10046.9 EKX32753.1 - 0.017 15.4 5.8 0.023 15.0 1.8 2.8 3 0 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 EKX32753.1 - 0.027 14.5 0.4 0.07 13.2 0.1 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4686 PF15742.5 EKX32753.1 - 0.032 13.4 15.9 0.057 12.5 15.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) AAA PF00004.29 EKX32753.1 - 0.049 14.1 0.1 0.21 12.0 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) XhlA PF10779.9 EKX32753.1 - 0.062 13.5 2.0 3.5 7.9 0.1 2.7 2 0 0 2 2 2 0 Haemolysin XhlA GvpD PF07088.11 EKX32753.1 - 0.09 11.4 0.0 0.28 9.8 0.0 1.7 2 0 0 2 2 2 0 GvpD gas vesicle protein AAA_19 PF13245.6 EKX32753.1 - 0.13 12.6 1.4 0.32 11.3 0.1 2.1 2 1 0 2 2 2 0 AAA domain Tektin PF03148.14 EKX32753.1 - 0.13 11.0 10.1 0.22 10.2 10.1 1.3 1 0 0 1 1 1 0 Tektin family Laminin_II PF06009.12 EKX32753.1 - 0.36 10.8 5.7 0.43 10.6 4.1 1.9 1 1 1 2 2 2 0 Laminin Domain II NPV_P10 PF05531.12 EKX32753.1 - 0.42 11.1 6.9 1.6 9.2 5.5 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein MCPsignal PF00015.21 EKX32753.1 - 0.48 10.2 10.9 0.75 9.6 10.9 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain T3SSipB PF16535.5 EKX32753.1 - 1.2 9.6 10.3 1.1 9.7 6.8 2.1 1 1 1 2 2 2 0 Type III cell invasion protein SipB FlaC_arch PF05377.11 EKX32753.1 - 1.5 9.3 4.9 12 6.4 0.3 2.7 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 EKX32753.1 - 3.1 6.6 16.5 0.32 9.8 1.9 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 EKX32753.1 - 3.7 5.4 5.2 0.7 7.7 1.0 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Laminin_I PF06008.14 EKX32753.1 - 5.6 6.6 14.1 0.038 13.7 2.2 2.3 1 1 2 3 3 3 0 Laminin Domain I COG2 PF06148.11 EKX32753.1 - 6.2 6.9 12.8 0.46 10.6 0.7 3.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Golgin_A5 PF09787.9 EKX32753.1 - 6.9 6.0 13.6 20 4.5 13.6 1.7 1 1 0 1 1 1 0 Golgin subfamily A member 5 PKD_channel PF08016.12 EKX32754.1 - 1.1e-22 80.4 19.6 1.3e-17 63.7 10.4 2.4 2 0 0 2 2 2 2 Polycystin cation channel C2 PF00168.30 EKX32754.1 - 8.1e-20 71.0 0.0 1.9e-19 69.8 0.0 1.7 1 0 0 1 1 1 1 C2 domain CUB PF00431.20 EKX32754.1 - 1.2e-17 64.2 0.5 3.3e-17 62.8 0.5 1.8 1 0 0 1 1 1 1 CUB domain Ion_trans PF00520.31 EKX32754.1 - 6.6e-11 41.9 16.9 2.5e-10 40.0 16.9 1.9 1 1 0 1 1 1 1 Ion transport protein EF-hand_5 PF13202.6 EKX32754.1 - 0.038 13.5 1.9 0.042 13.4 0.1 2.1 2 0 0 2 2 2 0 EF hand DUF962 PF06127.11 EKX32754.1 - 0.11 12.6 0.3 1 9.5 0.3 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF962) Phasin_2 PF09361.10 EKX32755.1 - 0.0061 16.8 1.5 0.025 14.8 1.5 2.1 1 0 0 1 1 1 1 Phasin protein Nsp3_PL2pro PF12124.8 EKX32755.1 - 0.008 15.9 0.0 0.19 11.6 0.0 2.7 3 0 0 3 3 3 1 Coronavirus polyprotein cleavage domain DUF2294 PF10057.9 EKX32755.1 - 1.5 9.0 6.0 11 6.2 0.2 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2294) COesterase PF00135.28 EKX32757.1 - 3.3e-09 36.2 0.4 0.0012 17.8 0.1 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EKX32757.1 - 5.8e-06 26.3 2.3 0.0044 16.9 0.2 3.1 2 1 1 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EKX32757.1 - 0.00057 19.4 0.8 0.034 13.6 0.0 2.4 3 0 0 3 3 3 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EKX32757.1 - 0.003 16.9 0.1 0.25 10.6 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Esterase PF00756.20 EKX32757.1 - 0.007 16.0 0.3 0.039 13.6 0.0 2.1 1 1 1 2 2 2 1 Putative esterase WD40 PF00400.32 EKX32758.1 - 5.9e-23 80.7 15.3 0.0022 18.8 0.0 10.0 9 1 1 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX32758.1 - 8e-08 32.5 0.0 0.2 12.0 0.0 5.7 4 2 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain HELP PF03451.14 EKX32758.1 - 0.0015 18.3 0.0 0.0036 17.1 0.0 1.6 1 1 0 1 1 1 1 HELP motif Carb_anhydrase PF00194.21 EKX32759.1 - 1.1e-39 136.5 3.7 1.9e-39 135.7 3.7 1.4 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase AbiH PF14253.6 EKX32759.1 - 0.049 13.5 1.7 0.091 12.6 1.7 1.6 1 1 0 1 1 1 0 Bacteriophage abortive infection AbiH GFP PF01353.22 EKX32760.1 - 0.21 11.0 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Green fluorescent protein Pkinase PF00069.25 EKX32761.1 - 1.3e-71 241.1 0.0 1.6e-71 240.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX32761.1 - 1.6e-39 135.7 0.0 2e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX32761.1 - 0.00017 21.0 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EKX32761.1 - 0.00027 20.4 0.0 0.00061 19.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EKX32761.1 - 0.00052 18.9 0.0 0.0008 18.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX32761.1 - 0.02 14.8 0.0 0.083 12.8 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family ABC2_membrane PF01061.24 EKX32762.1 - 4.8e-38 130.7 14.7 4.8e-38 130.7 14.7 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EKX32762.1 - 1.7e-25 90.2 0.0 2.4e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EKX32762.1 - 2e-05 25.1 0.0 3.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EKX32762.1 - 9.6e-05 22.3 0.9 0.084 12.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EKX32762.1 - 0.00038 20.4 0.1 0.00072 19.5 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 EKX32762.1 - 0.00081 19.0 0.0 0.014 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EKX32762.1 - 0.029 14.3 0.1 0.87 9.5 0.1 2.4 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 EKX32762.1 - 0.031 14.4 0.2 0.058 13.5 0.2 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_35 PF14516.6 EKX32762.1 - 0.055 12.3 0.0 0.083 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_28 PF13521.6 EKX32762.1 - 0.06 13.6 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EKX32762.1 - 0.076 13.6 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EKX32762.1 - 0.077 12.0 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 EKX32762.1 - 0.1 12.3 0.2 0.25 11.1 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 EKX32762.1 - 0.16 12.0 1.1 0.27 11.3 1.1 1.3 1 0 0 1 1 1 0 Dynamin family KAP_NTPase PF07693.14 EKX32762.1 - 0.19 10.9 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain DUF87 PF01935.17 EKX32762.1 - 0.2 11.7 0.9 0.33 11.0 0.9 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain SMC_N PF02463.19 EKX32762.1 - 0.22 10.9 0.2 2.6 7.4 0.2 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain PRK PF00485.18 EKX32762.1 - 0.25 11.1 0.2 0.4 10.4 0.2 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ABC2_membrane_3 PF12698.7 EKX32762.1 - 0.85 8.7 20.0 0.3 10.1 17.3 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein PDZ_6 PF17820.1 EKX32763.1 - 1e-08 34.9 0.1 2.5e-08 33.6 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX32763.1 - 3.7e-08 33.6 0.0 1.1e-07 32.0 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX32763.1 - 3.8e-06 27.2 0.2 1.1e-05 25.7 0.1 1.9 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 EKX32763.1 - 0.00042 20.2 0.0 0.0013 18.6 0.0 1.8 1 0 0 1 1 1 1 Tricorn protease PDZ domain CENP-F_leu_zip PF10473.9 EKX32763.1 - 0.0054 16.8 17.6 0.0054 16.8 17.6 3.5 1 1 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 EKX32763.1 - 0.073 12.4 42.2 0.043 13.1 10.4 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 EKX32763.1 - 5.3 7.2 57.4 0.47 10.7 12.8 3.5 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) ATG16 PF08614.11 EKX32764.1 - 0.076 13.2 16.6 0.21 11.8 16.6 1.7 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 EKX32764.1 - 0.082 13.0 11.7 0.12 12.4 1.3 3.2 3 1 0 3 3 3 0 bZIP transcription factor DUF1542 PF07564.11 EKX32764.1 - 0.092 12.9 9.0 2.2 8.5 0.8 2.5 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1542) Swi5 PF07061.11 EKX32764.1 - 0.14 12.3 9.7 0.82 9.8 2.6 2.7 2 0 0 2 2 2 0 Swi5 DUF724 PF05266.14 EKX32764.1 - 0.14 12.0 10.3 0.56 10.0 4.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) ZapB PF06005.12 EKX32764.1 - 0.25 11.8 16.7 3.8 8.0 2.5 3.0 1 1 2 3 3 3 0 Cell division protein ZapB APC_N_CC PF16689.5 EKX32764.1 - 0.36 10.9 6.2 32 4.7 0.5 3.7 2 1 1 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain CotJB PF12652.7 EKX32764.1 - 0.37 11.0 4.2 8.1 6.7 0.3 3.3 1 1 2 3 3 3 0 CotJB protein Gp58 PF07902.11 EKX32764.1 - 0.49 8.6 6.4 0.72 8.1 6.4 1.1 1 0 0 1 1 1 0 gp58-like protein DUF573 PF04504.14 EKX32764.1 - 0.61 10.8 7.7 5.6 7.7 1.1 3.3 1 1 2 3 3 3 0 Protein of unknown function, DUF573 Spc7 PF08317.11 EKX32764.1 - 0.74 8.6 16.4 1.6 7.5 16.4 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein PhoU PF01895.19 EKX32764.1 - 1 9.8 15.7 6 7.4 6.0 2.6 1 1 1 2 2 2 0 PhoU domain OmpH PF03938.14 EKX32764.1 - 1.1 9.5 20.8 1 9.7 10.2 2.6 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Ax_dynein_light PF10211.9 EKX32764.1 - 2.1 8.3 17.8 3.6 7.5 8.1 2.4 1 1 1 2 2 2 0 Axonemal dynein light chain AAA_11 PF13086.6 EKX32764.1 - 2.1 8.1 8.7 4.8 6.9 8.7 1.5 1 0 0 1 1 1 0 AAA domain Cep57_CLD_2 PF14197.6 EKX32764.1 - 2.3 8.4 21.7 0.87 9.7 5.1 4.1 2 2 1 3 3 3 0 Centrosome localisation domain of PPC89 FUSC PF04632.12 EKX32764.1 - 2.6 6.5 4.6 3.6 6.0 4.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4407 PF14362.6 EKX32764.1 - 2.7 7.3 12.8 5.3 6.3 12.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Arm-DNA-bind_5 PF17293.2 EKX32764.1 - 2.7 8.5 16.0 8.5 6.9 3.8 3.5 1 1 2 3 3 3 0 Arm DNA-binding domain Fungal_TACC PF12709.7 EKX32764.1 - 3 8.4 15.4 0.41 11.1 1.9 3.1 3 0 0 3 3 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Peptidase_S49_N PF08496.10 EKX32764.1 - 3.7 7.6 9.8 25 4.9 6.1 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Thioredoxin PF00085.20 EKX32765.1 - 3.8e-12 46.1 0.0 4.2e-12 46.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EKX32765.1 - 0.067 12.5 0.1 0.072 12.4 0.1 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family DUF2368 PF10166.9 EKX32766.1 - 0.084 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) Sec1 PF00995.23 EKX32767.1 - 1.3e-40 140.2 0.0 1.5e-40 140.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Aminotran_5 PF00266.19 EKX32768.1 - 4.9e-65 219.9 0.9 4.8e-36 124.5 0.0 2.2 1 1 1 2 2 2 2 Aminotransferase class-V LRR_8 PF13855.6 EKX32768.1 - 5.8e-27 93.2 11.2 1.1e-15 57.2 3.0 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EKX32768.1 - 2.3e-08 34.2 8.2 1.8e-05 25.0 2.4 2.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX32768.1 - 1.5e-07 31.5 0.0 2.6e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) Cys_Met_Meta_PP PF01053.20 EKX32768.1 - 0.00056 18.5 0.0 0.00097 17.8 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EKX32768.1 - 0.0007 18.9 0.2 0.71 9.0 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class I and II LRR_1 PF00560.33 EKX32768.1 - 0.0014 18.9 2.0 1.2 10.0 0.2 4.0 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 EKX32768.1 - 0.011 15.7 5.4 0.9 9.8 0.1 3.6 3 0 0 3 3 3 0 Leucine Rich repeat DegT_DnrJ_EryC1 PF01041.17 EKX32768.1 - 0.095 12.0 0.4 0.14 11.5 0.4 1.1 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family ATG27 PF09451.10 EKX32769.1 - 2.2e-10 40.8 1.1 1.5e-06 28.3 0.1 2.5 2 1 0 2 2 2 2 Autophagy-related protein 27 GAPT PF11770.8 EKX32769.1 - 0.21 11.4 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) PLAT PF01477.23 EKX32770.1 - 2.6e-13 50.6 0.0 4.5e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 PLAT/LH2 domain SpoIIE PF07228.12 EKX32770.1 - 8.2e-09 35.7 0.0 0.0034 17.3 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EKX32770.1 - 8.3e-05 22.3 0.0 0.057 13.0 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EKX32770.1 - 0.00027 20.6 0.0 0.00051 19.7 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C Mg_trans_NIPA PF05653.14 EKX32771.1 - 1.6e-16 60.3 19.4 4e-16 59.0 19.5 1.5 2 0 0 2 2 2 1 Magnesium transporter NIPA EamA PF00892.20 EKX32771.1 - 0.00052 20.2 2.8 0.00052 20.2 2.8 3.4 2 1 1 3 3 3 1 EamA-like transporter family SieB PF14163.6 EKX32771.1 - 0.06 12.8 4.1 0.81 9.2 0.4 2.9 3 0 0 3 3 3 0 Super-infection exclusion protein B OSTbeta PF15048.6 EKX32771.1 - 0.23 11.6 0.0 0.23 11.6 0.0 2.7 3 0 0 3 3 3 0 Organic solute transporter subunit beta protein DUF2371 PF10177.9 EKX32771.1 - 5.8 7.1 9.8 16 5.6 0.0 4.4 4 1 1 5 5 5 0 Uncharacterised conserved protein (DUF2371) LisH_2 PF16045.5 EKX32772.1 - 0.53 9.4 3.0 2.2 7.4 0.1 2.9 3 0 0 3 3 3 0 LisH LRR_8 PF13855.6 EKX32774.1 - 2.1e-52 174.7 54.8 2.1e-15 56.2 5.5 7.0 1 1 7 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 EKX32774.1 - 1.3e-22 79.5 37.8 0.00013 22.2 1.4 7.0 3 2 0 6 6 6 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX32774.1 - 1.3e-22 80.1 9.0 2.8e-12 46.7 6.7 3.2 1 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EKX32774.1 - 1.5e-08 34.0 22.9 1.7 9.5 0.2 9.2 9 1 0 9 9 9 4 Leucine Rich Repeat LRR_9 PF14580.6 EKX32774.1 - 1.4e-05 24.7 9.2 0.22 11.0 0.0 4.0 1 1 3 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 EKX32774.1 - 4.9e-05 23.0 35.2 3.7 7.8 0.2 8.9 9 0 0 9 9 9 5 Leucine Rich repeat EppA_BapA PF07268.11 EKX32774.1 - 0.17 11.8 0.2 17 5.4 0.0 2.6 2 0 0 2 2 2 0 Exported protein precursor (EppA/BapA) WD40 PF00400.32 EKX32776.1 - 1.3e-20 73.3 28.5 0.0058 17.5 1.0 6.9 6 1 0 6 6 6 6 WD domain, G-beta repeat DUF1921 PF09081.10 EKX32776.1 - 0.032 14.5 0.0 0.16 12.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1921) LRR_8 PF13855.6 EKX32777.1 - 8.7e-37 124.7 34.2 2.2e-16 59.3 3.4 4.1 1 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 EKX32777.1 - 4.5e-17 61.9 22.6 2.3e-06 27.8 1.1 4.4 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX32777.1 - 1.4e-16 60.6 1.7 2.6e-12 46.8 3.8 2.1 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EKX32777.1 - 3.8e-08 32.8 10.3 0.15 12.7 0.1 6.1 5 1 0 5 5 5 3 Leucine Rich Repeat LRR_9 PF14580.6 EKX32777.1 - 1.5e-05 24.6 1.5 0.0062 16.1 0.4 2.3 1 1 2 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 EKX32777.1 - 0.00031 20.6 25.1 0.18 11.9 0.2 6.0 6 0 0 6 6 6 4 Leucine Rich repeat ATP-synt_C PF00137.21 EKX32778.1 - 1.2e-33 115.2 38.3 7.5e-19 67.8 15.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C GerA PF03323.13 EKX32778.1 - 4 5.8 5.6 14 4.0 1.3 2.2 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein ATP-synt_C PF00137.21 EKX32779.1 - 7.2e-33 112.7 39.5 6.4e-21 74.5 14.8 2.2 2 0 0 2 2 2 2 ATP synthase subunit C Porin_OmpL1 PF11389.8 EKX32780.1 - 0.0072 15.6 0.2 0.0078 15.5 0.2 1.1 1 0 0 1 1 1 1 Leptospira porin protein OmpL1 Alpha_adaptinC2 PF02883.20 EKX32780.1 - 0.0081 16.5 0.4 0.012 16.0 0.4 1.3 1 0 0 1 1 1 1 Adaptin C-terminal domain AsmA_2 PF13502.6 EKX32781.1 - 0.0023 17.5 0.0 0.0034 17.0 0.0 1.2 1 0 0 1 1 1 1 AsmA-like C-terminal region DUF2723 PF11028.8 EKX32782.1 - 6.3e-31 107.6 4.2 6.3e-31 107.6 4.2 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2723) PMT_2 PF13231.6 EKX32782.1 - 7.8e-07 29.5 8.5 7.8e-07 29.5 8.5 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Tim54 PF11711.8 EKX32782.1 - 0.17 10.6 0.2 0.27 10.0 0.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF1772 PF08592.11 EKX32782.1 - 2.2 8.6 8.6 7.8 6.8 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) DUF2079 PF09852.9 EKX32782.1 - 3.7 6.3 15.0 0.11 11.4 7.2 2.4 3 1 0 3 3 3 0 Predicted membrane protein (DUF2079) PRP3 PF08572.10 EKX32783.1 - 2.7e-44 151.6 13.2 2.7e-44 151.6 13.2 2.0 3 0 0 3 3 3 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 EKX32783.1 - 2e-34 118.8 0.7 2e-34 118.8 0.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) DUF3437 PF11919.8 EKX32783.1 - 0.08 12.9 0.3 0.18 11.8 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) DUF3899 PF13038.6 EKX32783.1 - 1.1 9.7 0.0 1.1 9.7 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3899) YjbH PF06082.11 EKX32784.1 - 1.8 7.3 6.1 2.4 6.8 6.1 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Hexapep PF00132.24 EKX32785.1 - 5.7e-13 48.0 11.4 1.2e-06 28.0 0.6 3.8 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EKX32785.1 - 2.4e-06 27.2 7.8 0.00037 20.2 2.4 3.4 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Pepsin-I3 PF06394.13 EKX32785.1 - 0.0038 17.4 0.0 0.0093 16.1 0.0 1.6 1 0 0 1 1 1 1 Pepsin inhibitor-3-like repeated domain SRP_TPR_like PF17004.5 EKX32786.1 - 5.2e-18 65.2 6.5 1.9e-17 63.3 0.3 3.7 4 0 0 4 4 4 1 Putative TPR-like repeat TPR_19 PF14559.6 EKX32786.1 - 1.3e-16 60.9 24.8 0.0001 22.8 0.0 7.0 5 1 1 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 EKX32786.1 - 2e-12 47.5 17.7 0.039 14.6 2.1 6.7 4 1 1 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 EKX32786.1 - 3.7e-12 45.4 17.5 0.015 15.4 0.0 8.0 9 0 0 9 9 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX32786.1 - 2.4e-11 43.7 19.1 2.3e-06 27.7 0.4 6.2 4 2 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EKX32786.1 - 4.4e-11 42.6 25.2 0.23 12.4 0.0 10.0 8 3 3 11 11 10 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX32786.1 - 2.3e-06 27.8 18.3 1.9 8.9 0.0 6.9 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX32786.1 - 2.4e-06 27.3 13.9 0.45 10.9 0.4 7.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX32786.1 - 4.5e-06 26.3 17.2 0.98 9.3 0.0 7.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX32786.1 - 0.00011 21.9 9.8 4.9 7.4 0.1 7.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX32786.1 - 0.00012 22.5 23.8 4.7 8.1 0.1 8.0 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_21 PF09976.9 EKX32786.1 - 0.0013 18.5 28.8 0.0023 17.7 4.7 4.7 3 2 1 4 4 4 2 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 EKX32786.1 - 0.0027 18.2 7.5 3.9 8.4 0.3 5.0 4 0 0 4 4 3 2 Tetratricopeptide repeat UreE_N PF02814.15 EKX32786.1 - 0.32 10.6 2.9 7.9 6.2 0.0 3.2 3 0 0 3 3 3 0 UreE urease accessory protein, N-terminal domain TPR_17 PF13431.6 EKX32786.1 - 0.58 10.7 9.1 85 3.9 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 EKX32786.1 - 0.68 10.1 22.7 1.5 9.0 0.1 7.0 7 1 1 8 8 8 0 Tetratricopeptide repeat Ank_2 PF12796.7 EKX32787.1 - 3.2e-26 91.7 0.0 9.9e-08 32.5 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX32787.1 - 1.9e-23 82.5 0.0 1.5e-06 28.7 0.0 4.1 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX32787.1 - 9.6e-20 70.4 0.3 0.015 15.6 0.0 5.4 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX32787.1 - 6.6e-17 59.9 0.0 0.04 14.5 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 EKX32787.1 - 1.6e-09 37.7 0.0 6.3 7.4 0.0 5.8 6 0 0 6 6 6 2 Ankyrin repeat Herpes_UL33 PF03581.13 EKX32787.1 - 0.012 16.0 0.6 4.9 7.6 0.1 3.2 3 0 0 3 3 3 0 Herpesvirus UL33-like protein Ins_beta PF03488.14 EKX32787.1 - 0.017 15.1 1.0 19 5.4 0.1 3.4 4 0 0 4 4 4 0 Nematode insulin-related peptide beta type VHS PF00790.19 EKX32787.1 - 0.25 11.2 0.2 51 3.7 0.0 3.0 3 0 0 3 3 3 0 VHS domain ShK PF01549.24 EKX32787.1 - 0.76 10.4 2.9 48 4.6 0.0 3.5 3 0 0 3 3 3 0 ShK domain-like BLIP PF07467.11 EKX32788.1 - 0.13 12.8 12.8 0.39 11.3 4.5 2.2 1 1 1 2 2 2 0 Beta-lactamase inhibitor (BLIP) DUF3657 PF12394.8 EKX32788.1 - 2.2 8.9 6.0 2.3e+02 2.4 6.0 3.9 1 1 0 1 1 1 0 Protein FAM135 Pkinase_Tyr PF07714.17 EKX32790.1 - 9e-38 130.0 0.0 1e-37 129.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX32790.1 - 5.2e-14 52.2 0.0 5.8e-14 52.1 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain U-box PF04564.15 EKX32791.1 - 1.9e-19 69.6 0.0 2.2e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX32791.1 - 1.5e-05 24.7 0.0 2.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EKX32791.1 - 0.00018 21.4 0.1 0.00029 20.8 0.1 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-NOSIP PF15906.5 EKX32791.1 - 0.0058 16.7 0.0 0.0072 16.4 0.0 1.1 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein DUF1090 PF06476.12 EKX32792.1 - 2.4e-05 24.4 64.2 0.42 10.8 2.0 10.6 4 2 8 12 12 12 8 Protein of unknown function (DUF1090) Glyco_hydro_46 PF01374.18 EKX32792.1 - 7.2e-05 22.5 12.6 2.9 7.4 0.2 5.6 2 2 5 7 7 7 3 Glycosyl hydrolase family 46 DUF3769 PF12600.8 EKX32792.1 - 0.0032 16.4 6.6 1.5 7.6 0.1 4.0 2 1 3 5 5 5 2 Protein of unknown function (DUF3769) Peptidase_U32_C PF16325.5 EKX32792.1 - 0.095 13.0 14.8 18 5.7 0.2 6.3 4 3 3 7 7 7 0 Peptidase family U32 C-terminal domain DUF4170 PF13773.6 EKX32792.1 - 0.16 12.2 0.0 18 5.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4170) UPF0556 PF10572.9 EKX32792.1 - 1.7 8.1 9.0 34 3.9 0.1 5.2 2 1 5 8 8 8 0 Uncharacterised protein family UPF0556 MoCF_biosynth PF00994.24 EKX32792.1 - 2.7 7.6 9.4 5.4 6.7 0.1 4.1 1 1 3 4 4 4 0 Probable molybdopterin binding domain Prefoldin_2 PF01920.20 EKX32792.1 - 7.1 6.6 31.6 7.2 6.6 0.7 7.5 4 2 5 9 9 9 0 Prefoldin subunit ART PF01129.18 EKX32793.1 - 3.7e-07 29.7 0.0 7.4e-07 28.7 0.0 1.5 1 1 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase ADPrib_exo_Tox PF03496.14 EKX32793.1 - 4.3e-06 26.2 0.0 1.1e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosyltransferase exoenzyme Lig_chan PF00060.26 EKX32794.1 - 0.0062 16.4 0.2 0.013 15.4 0.2 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel Pkinase_Tyr PF07714.17 EKX32795.1 - 2.4e-38 131.9 0.0 2.6e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX32795.1 - 4.2e-15 55.8 0.0 4.7e-15 55.7 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain U-box PF04564.15 EKX32796.1 - 6e-19 68.0 0.0 6.9e-19 67.8 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX32796.1 - 0.00019 21.2 0.0 0.00026 20.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EKX32796.1 - 0.00028 20.9 0.1 0.00043 20.2 0.1 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-NOSIP PF15906.5 EKX32796.1 - 0.045 13.9 0.0 0.057 13.5 0.0 1.2 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein DUF1090 PF06476.12 EKX32797.1 - 0.00067 19.8 21.6 0.79 9.9 1.7 4.5 1 1 3 4 4 4 4 Protein of unknown function (DUF1090) Glyco_hydro_46 PF01374.18 EKX32797.1 - 0.014 15.0 4.0 0.22 11.1 0.7 2.3 1 1 1 2 2 2 0 Glycosyl hydrolase family 46 Prefoldin_2 PF01920.20 EKX32797.1 - 0.027 14.4 6.1 1.2 9.2 0.4 2.9 1 1 2 3 3 3 0 Prefoldin subunit Peptidase_U32_C PF16325.5 EKX32797.1 - 0.081 13.2 0.5 5.9 7.2 0.1 2.8 1 1 2 3 3 3 0 Peptidase family U32 C-terminal domain DUF3769 PF12600.8 EKX32797.1 - 0.16 10.8 0.5 0.47 9.3 0.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3769) Ank_2 PF12796.7 EKX32798.1 - 2.8e-49 165.6 16.3 2.2e-09 37.7 0.1 5.8 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX32798.1 - 5.4e-47 157.6 10.1 5.2e-09 36.5 0.0 7.3 3 3 5 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX32798.1 - 2.1e-23 82.1 3.5 0.028 14.8 0.0 9.4 1 1 9 10 10 10 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX32798.1 - 1.7e-21 74.0 0.3 0.49 11.1 0.0 10.1 10 0 0 10 10 10 4 Ankyrin repeat Ank PF00023.30 EKX32798.1 - 6.9e-10 38.9 0.4 8.6 7.0 0.0 9.0 11 0 0 11 11 11 1 Ankyrin repeat SF3b10 PF07189.11 EKX32798.1 - 0.00013 22.0 0.4 64 3.8 0.0 6.3 9 1 1 10 10 10 0 Splicing factor 3B subunit 10 (SF3b10) LtuA PF17446.2 EKX32798.1 - 0.001 19.4 0.0 38 4.8 0.0 5.6 5 1 2 7 7 7 0 Late transcription unit A GluRS_N PF18466.1 EKX32798.1 - 0.0035 17.7 0.0 1.2e+02 3.2 0.0 6.0 7 0 0 7 7 7 0 Glutamate--tRNA ligase N-terminal domain RICTOR_V PF14668.6 EKX32798.1 - 0.0036 17.5 2.9 50 4.2 0.0 6.2 5 1 2 7 7 7 0 Rapamycin-insensitive companion of mTOR, domain 5 AsnC_trans_reg2 PF17805.1 EKX32798.1 - 0.0068 16.5 1.3 55 4.0 0.0 5.0 3 2 3 6 6 5 0 AsnC-like ligand binding domain Mo-nitro_C PF06967.11 EKX32798.1 - 0.035 14.1 8.0 1.2e+02 2.7 0.0 7.0 10 0 0 10 10 10 0 Mo-dependent nitrogenase C-terminus PI-PLC-X PF00388.19 EKX32798.1 - 0.059 12.9 0.4 13 5.3 0.0 4.1 2 1 3 5 5 5 0 Phosphatidylinositol-specific phospholipase C, X domain Ins_beta PF03488.14 EKX32798.1 - 0.15 12.1 13.1 82 3.3 0.1 6.6 7 0 0 7 7 7 0 Nematode insulin-related peptide beta type DUF4034 PF13226.6 EKX32798.1 - 0.35 10.2 9.3 13 5.1 0.1 5.2 3 2 3 6 6 6 0 Domain of unknown function (DUF4034) VHS PF00790.19 EKX32798.1 - 0.37 10.6 2.9 2.6e+02 1.4 0.0 5.4 7 0 0 7 7 7 0 VHS domain Ank_2 PF12796.7 EKX32799.1 - 1.4e-06 28.8 0.0 0.00011 22.7 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX32799.1 - 2.9e-06 27.7 0.0 0.024 15.2 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX32799.1 - 0.00022 21.5 0.0 0.054 13.8 0.0 3.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) UCR_Fe-S_N PF10399.9 EKX32799.1 - 0.016 14.6 0.2 0.026 13.8 0.2 1.3 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Ank_3 PF13606.6 EKX32799.1 - 0.026 15.0 0.0 3.5 8.5 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat Ank PF00023.30 EKX32799.1 - 0.15 12.6 0.0 0.44 11.1 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeat Arm PF00514.23 EKX32800.1 - 2.7e-18 65.3 7.7 0.00025 21.0 0.1 4.6 4 0 0 4 4 4 4 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EKX32800.1 - 7.6e-09 35.5 0.0 0.022 14.8 0.0 4.1 1 1 3 4 4 4 3 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 EKX32800.1 - 3.9e-05 23.3 0.5 6e-05 22.6 0.5 1.3 1 0 0 1 1 1 1 Armadillo-like HEAT_EZ PF13513.6 EKX32800.1 - 0.00048 20.6 5.7 0.00092 19.7 0.3 3.0 3 0 0 3 3 3 1 HEAT-like repeat UME PF08064.13 EKX32800.1 - 0.0021 17.9 4.9 2 8.4 0.3 3.3 1 1 0 3 3 3 2 UME (NUC010) domain Pkinase_Tyr PF07714.17 EKX32801.1 - 9.1e-19 67.7 0.0 9.8e-19 67.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX32801.1 - 0.0063 15.9 0.0 0.0098 15.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain U-box PF04564.15 EKX32802.1 - 4.5e-18 65.2 0.0 5.2e-18 65.0 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX32802.1 - 0.00018 21.2 0.0 0.00028 20.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EKX32802.1 - 0.00028 20.8 0.2 0.00047 20.1 0.2 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-NOSIP PF15906.5 EKX32802.1 - 0.036 14.2 0.0 0.044 13.9 0.0 1.1 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein DUF1090 PF06476.12 EKX32803.1 - 3.1e-05 24.0 27.2 0.12 12.5 2.2 5.3 1 1 5 6 6 6 6 Protein of unknown function (DUF1090) Glyco_hydro_46 PF01374.18 EKX32803.1 - 0.0063 16.2 1.8 1.8 8.1 0.1 2.9 1 1 3 4 4 4 3 Glycosyl hydrolase family 46 DUF2125 PF09898.9 EKX32803.1 - 0.031 13.9 9.0 0.24 11.0 4.3 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2125) DUF3769 PF12600.8 EKX32803.1 - 0.037 12.9 1.5 0.65 8.8 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3769) Peptidase_U32_C PF16325.5 EKX32803.1 - 0.064 13.5 5.1 7.7 6.9 0.4 3.9 2 2 1 3 3 3 0 Peptidase family U32 C-terminal domain MoCF_biosynth PF00994.24 EKX32803.1 - 0.43 10.2 6.4 1.9 8.2 0.1 3.2 1 1 1 3 3 3 0 Probable molybdopterin binding domain DUF4508 PF14969.6 EKX32804.1 - 0.0026 18.0 0.1 0.0047 17.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4508) LMBR1 PF04791.16 EKX32805.1 - 2.7 6.8 5.6 3.7 6.4 5.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Pkinase_Tyr PF07714.17 EKX32806.1 - 2.3e-67 227.0 0.0 3e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX32806.1 - 2.3e-32 112.4 0.0 2.9e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain zf-C3HC4_3 PF13920.6 EKX32806.1 - 2.8e-11 43.1 10.5 4.7e-11 42.4 10.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX32806.1 - 5e-07 29.5 9.6 5e-07 29.5 9.6 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 TP2 PF01254.18 EKX32810.1 - 6 7.5 11.7 6.6 7.3 2.6 2.7 2 0 0 2 2 2 0 Nuclear transition protein 2 Extensin_2 PF04554.13 EKX32812.1 - 0.053 13.6 4.9 0.12 12.4 2.4 2.6 1 1 1 2 2 2 0 Extensin-like region RelA_SpoT PF04607.17 EKX32813.1 - 0.0021 18.3 0.4 0.66 10.3 0.0 2.8 2 0 0 2 2 2 2 Region found in RelA / SpoT proteins DUF3944 PF13099.6 EKX32813.1 - 0.38 10.7 2.0 28 4.7 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3944) RelA_SpoT PF04607.17 EKX32814.1 - 0.00072 19.8 0.4 0.58 10.5 0.0 2.8 2 0 0 2 2 2 2 Region found in RelA / SpoT proteins DUF3944 PF13099.6 EKX32814.1 - 0.37 10.7 2.0 28 4.7 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3944) Lebercilin PF15619.6 EKX32815.1 - 7.6e-05 22.5 12.5 0.0001 22.1 12.5 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Atg14 PF10186.9 EKX32815.1 - 0.00035 19.8 11.4 0.00046 19.4 11.4 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Tropomyosin_1 PF12718.7 EKX32815.1 - 0.00047 20.3 15.9 0.001 19.2 15.9 1.5 1 1 0 1 1 1 1 Tropomyosin like HMMR_N PF15905.5 EKX32815.1 - 0.0013 18.3 13.9 0.0014 18.2 13.9 1.0 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Corona_S2 PF01601.16 EKX32815.1 - 0.002 16.7 1.4 0.0024 16.5 1.4 1.1 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein Baculo_PEP_C PF04513.12 EKX32815.1 - 0.003 17.6 2.9 0.004 17.2 2.9 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.12 EKX32815.1 - 0.0033 18.0 8.1 0.0034 18.0 2.6 2.9 1 1 2 3 3 3 1 SlyX GAT PF03127.14 EKX32815.1 - 0.004 17.4 6.1 0.038 14.3 1.2 2.3 2 0 0 2 2 2 1 GAT domain PHM7_cyt PF14703.6 EKX32815.1 - 0.0058 16.9 2.7 0.0071 16.6 2.7 1.1 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Tropomyosin PF00261.20 EKX32815.1 - 0.0061 15.9 3.5 0.0061 15.9 3.5 2.1 1 1 1 2 2 2 1 Tropomyosin DUF948 PF06103.11 EKX32815.1 - 0.008 16.4 4.1 0.99 9.7 1.0 2.4 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF948) TPR_MLP1_2 PF07926.12 EKX32815.1 - 0.0088 16.1 13.7 0.013 15.5 13.0 1.6 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein CorA PF01544.18 EKX32815.1 - 0.011 15.1 5.0 0.013 14.8 5.0 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Dor1 PF04124.12 EKX32815.1 - 0.012 14.3 6.3 0.015 14.0 6.3 1.1 1 0 0 1 1 1 0 Dor1-like family Phage_Mu_Gam PF07352.12 EKX32815.1 - 0.015 15.2 0.3 0.015 15.2 0.3 2.0 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein ArsR PF09824.9 EKX32815.1 - 0.025 14.2 1.6 0.03 13.9 0.8 1.5 1 1 0 1 1 1 0 ArsR transcriptional regulator Fib_alpha PF08702.10 EKX32815.1 - 0.027 14.6 6.4 0.028 14.6 5.3 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.9 EKX32815.1 - 0.028 14.7 12.2 0.17 12.2 4.0 2.7 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LXG PF04740.12 EKX32815.1 - 0.035 13.8 5.8 0.13 11.9 0.5 2.1 1 1 0 1 1 1 0 LXG domain of WXG superfamily EzrA PF06160.12 EKX32815.1 - 0.04 12.1 9.0 0.051 11.8 9.0 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Spc7 PF08317.11 EKX32815.1 - 0.043 12.7 13.5 0.051 12.4 13.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.15 EKX32815.1 - 0.045 13.5 1.5 0.045 13.5 1.5 3.1 1 1 2 3 3 3 0 Septum formation initiator DHR10 PF18595.1 EKX32815.1 - 0.054 13.5 14.7 0.13 12.3 14.7 1.6 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain AAA_13 PF13166.6 EKX32815.1 - 0.074 11.7 7.2 0.086 11.5 7.2 1.1 1 0 0 1 1 1 0 AAA domain TMCO5 PF14992.6 EKX32815.1 - 0.08 12.5 9.9 0.1 12.2 9.9 1.2 1 0 0 1 1 1 0 TMCO5 family DUF812 PF05667.11 EKX32815.1 - 0.081 11.8 9.6 0.1 11.4 9.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF16 PF01519.16 EKX32815.1 - 0.093 13.2 8.1 0.42 11.1 8.2 1.9 1 1 0 1 1 1 0 Protein of unknown function DUF16 Laminin_II PF06009.12 EKX32815.1 - 0.15 12.1 11.9 0.21 11.6 10.1 1.8 1 1 1 2 2 2 0 Laminin Domain II DUF5403 PF17395.2 EKX32815.1 - 0.15 12.3 0.1 0.32 11.3 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5403) Sec2p PF06428.11 EKX32815.1 - 0.15 12.0 12.1 1.1 9.3 7.1 2.6 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p V_ATPase_I PF01496.19 EKX32815.1 - 0.17 9.8 6.0 0.2 9.5 6.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec34 PF04136.15 EKX32815.1 - 0.17 11.7 8.6 0.46 10.4 2.6 2.1 1 1 1 2 2 2 0 Sec34-like family HAP1_N PF04849.13 EKX32815.1 - 0.27 10.4 14.0 0.32 10.1 14.0 1.1 1 0 0 1 1 1 0 HAP1 N-terminal conserved region NPV_P10 PF05531.12 EKX32815.1 - 0.29 11.6 5.5 7.1 7.2 5.5 2.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein UPF0242 PF06785.11 EKX32815.1 - 0.3 11.2 10.3 0.47 10.5 10.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CENP-H PF05837.12 EKX32815.1 - 0.3 11.5 13.3 2.8 8.4 13.3 2.1 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Exonuc_VII_L PF02601.15 EKX32815.1 - 0.31 10.6 7.4 0.36 10.3 7.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit GCN5L1 PF06320.13 EKX32815.1 - 0.38 10.9 8.4 1.6 8.9 1.8 2.2 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) Prefoldin_2 PF01920.20 EKX32815.1 - 0.38 10.7 14.2 8.8 6.3 14.2 2.4 1 1 0 1 1 1 0 Prefoldin subunit Spectrin PF00435.21 EKX32815.1 - 0.42 11.1 9.1 1.5 9.3 8.6 2.0 1 1 1 2 2 2 0 Spectrin repeat ZapB PF06005.12 EKX32815.1 - 0.44 11.0 17.4 0.12 12.8 4.0 2.6 1 1 1 2 2 2 0 Cell division protein ZapB DUF3552 PF12072.8 EKX32815.1 - 0.47 9.8 14.0 2.5 7.5 14.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) APG6_N PF17675.1 EKX32815.1 - 0.56 10.7 15.7 3.7 8.1 5.8 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF1664 PF07889.12 EKX32815.1 - 0.58 10.2 7.6 0.21 11.6 2.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4446 PF14584.6 EKX32815.1 - 0.73 9.8 7.7 2.4 8.1 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) FapA PF03961.13 EKX32815.1 - 0.79 8.3 9.1 0.98 7.9 9.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A HAUS-augmin3 PF14932.6 EKX32815.1 - 0.81 9.2 11.4 4.1 6.9 11.4 1.9 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 ATG16 PF08614.11 EKX32815.1 - 0.89 9.7 16.4 2.2 8.5 14.9 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4164 PF13747.6 EKX32815.1 - 0.94 9.8 10.4 0.13 12.6 4.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) ADIP PF11559.8 EKX32815.1 - 1 9.5 12.5 2 8.5 12.4 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.6 EKX32815.1 - 1 9.8 11.6 8.2 6.9 11.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) COG5 PF10392.9 EKX32815.1 - 1 9.5 9.7 3.9 7.7 2.8 2.2 1 1 1 2 2 2 0 Golgi transport complex subunit 5 TMF_TATA_bd PF12325.8 EKX32815.1 - 1.1 9.5 15.5 0.18 12.1 3.3 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CHD5 PF04420.14 EKX32815.1 - 1.3 8.8 6.4 13 5.6 2.5 2.3 1 1 0 2 2 2 0 CHD5-like protein BRE1 PF08647.11 EKX32815.1 - 1.4 9.0 13.8 0.08 13.0 4.4 2.1 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF5344 PF17279.2 EKX32815.1 - 1.6 9.4 8.6 2.6 8.7 7.3 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5344) Nup88 PF10168.9 EKX32815.1 - 1.7 6.4 10.8 1.9 6.2 10.8 1.0 1 0 0 1 1 1 0 Nuclear pore component DUF724 PF05266.14 EKX32815.1 - 1.7 8.4 8.9 2.5 7.9 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) zf-C4H2 PF10146.9 EKX32815.1 - 2 8.7 7.9 2.5 8.4 7.9 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein DUF4795 PF16043.5 EKX32815.1 - 2 7.9 12.4 3.5 7.2 12.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) FAM76 PF16046.5 EKX32815.1 - 2.5 7.4 11.9 1.2 8.4 5.1 1.8 1 1 1 2 2 2 0 FAM76 protein DUF3450 PF11932.8 EKX32815.1 - 2.5 7.3 9.8 2.2 7.5 7.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) YabA PF06156.13 EKX32815.1 - 3 8.5 11.3 0.73 10.5 2.5 2.3 1 1 1 2 2 2 0 Initiation control protein YabA TMPIT PF07851.13 EKX32815.1 - 3.1 7.0 9.4 5.1 6.2 9.4 1.4 1 1 0 1 1 1 0 TMPIT-like protein LPP PF04728.13 EKX32815.1 - 5.3 7.5 7.7 5.9 7.4 3.8 2.9 2 1 1 3 3 3 0 Lipoprotein leucine-zipper DUF2175 PF09943.9 EKX32815.1 - 5.8 7.3 7.2 5.2 7.4 4.5 2.1 1 1 2 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) Spc24 PF08286.11 EKX32815.1 - 7.7 6.8 13.2 2.7 8.3 5.0 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 FTCD_C PF04961.12 EKX32816.1 - 0.056 13.2 7.2 0.95 9.2 1.9 2.3 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase BCAS3 PF12490.8 EKX32816.1 - 0.08 12.5 1.0 0.13 11.8 0.1 1.8 2 0 0 2 2 2 0 Breast carcinoma amplified sequence 3 DUF2937 PF11157.8 EKX32816.1 - 0.13 12.0 0.3 0.3 10.8 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) PriA_C PF18074.1 EKX32816.1 - 0.36 11.7 2.2 0.47 11.3 0.3 2.1 2 0 0 2 2 2 0 Primosomal protein N C-terminal domain HTH_3 PF01381.22 EKX32817.1 - 6.6e-13 48.5 0.0 7.1e-13 48.4 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EKX32817.1 - 0.00061 20.1 0.0 0.00063 20.0 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain SUKH_5 PF14567.6 EKX32817.1 - 0.15 11.8 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall Guanylate_cyc PF00211.20 EKX32818.1 - 4e-30 104.8 0.1 4.4e-30 104.7 0.1 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pyr_redox_2 PF07992.14 EKX32819.1 - 3.7e-39 134.7 0.3 5.2e-39 134.2 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EKX32819.1 - 8.6e-19 67.9 6.4 2.4e-16 60.1 0.2 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EKX32819.1 - 1.5e-13 51.0 0.8 2.3e-13 50.4 0.1 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Rhodanese PF00581.20 EKX32819.1 - 2.5e-09 37.6 0.0 6.3e-08 33.1 0.0 2.9 3 1 0 3 3 3 1 Rhodanese-like domain NAD_binding_8 PF13450.6 EKX32819.1 - 4.5e-09 36.4 1.4 0.002 18.3 0.1 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EKX32819.1 - 3.3e-08 33.2 0.1 2.8e-05 23.5 0.7 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EKX32819.1 - 4.9e-07 29.7 10.8 0.0023 17.6 1.5 3.6 3 1 1 4 4 4 3 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EKX32819.1 - 0.00025 21.4 2.6 0.059 13.8 0.3 2.8 3 1 0 3 3 3 1 Putative NAD(P)-binding NAD_binding_9 PF13454.6 EKX32819.1 - 0.00031 20.7 3.2 1.2 9.1 0.1 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding TrkA_N PF02254.18 EKX32819.1 - 0.0016 18.7 1.4 0.39 11.0 0.1 3.4 3 0 0 3 3 3 1 TrkA-N domain AlaDh_PNT_C PF01262.21 EKX32819.1 - 0.0047 16.2 0.5 0.69 9.2 0.0 2.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DUF1188 PF06690.11 EKX32819.1 - 0.006 16.2 0.0 0.1 12.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1188) 3HCDH_N PF02737.18 EKX32819.1 - 0.0085 16.0 0.1 0.018 14.9 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EKX32819.1 - 0.018 14.6 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 EKX32819.1 - 0.018 13.7 2.5 0.92 8.1 0.2 3.2 4 0 0 4 4 4 0 HI0933-like protein Thi4 PF01946.17 EKX32819.1 - 0.03 13.6 0.3 1.7 7.8 0.1 2.5 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 EKX32819.1 - 0.039 13.0 4.4 2.7 7.0 0.6 3.5 4 0 0 4 4 4 0 FAD binding domain Lycopene_cycl PF05834.12 EKX32819.1 - 0.055 12.5 1.3 0.66 9.0 0.1 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 EKX32819.1 - 0.075 12.3 3.4 0.069 12.4 0.5 2.2 3 0 0 3 3 3 0 FAD binding domain K_oxygenase PF13434.6 EKX32819.1 - 0.11 11.7 0.7 0.79 8.8 0.1 2.4 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 EKX32819.1 - 0.26 10.3 2.6 2.2 7.2 0.0 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 EKX32819.1 - 0.54 9.0 2.2 4.2 6.1 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase PDZ_6 PF17820.1 EKX32821.1 - 6.4e-11 41.9 0.2 1.3e-10 40.9 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX32821.1 - 5.4e-06 26.7 0.1 1.1e-05 25.7 0.1 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 EKX32821.1 - 0.03 14.6 0.0 0.053 13.8 0.0 1.4 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Atx10homo_assoc PF09759.9 EKX32822.1 - 0.00021 21.3 0.1 0.039 14.0 0.0 3.9 3 1 1 4 4 4 1 Spinocerebellar ataxia type 10 protein domain RIH_assoc PF08454.11 EKX32822.1 - 0.025 14.4 0.4 0.73 9.7 0.0 2.6 2 1 0 2 2 2 0 RyR and IP3R Homology associated TPP_enzyme_N PF02776.18 EKX32822.1 - 0.086 12.5 0.1 8.2 6.0 0.0 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPR_17 PF13431.6 EKX32823.1 - 5.7e-26 89.0 2.0 3.1e-05 24.1 0.0 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 EKX32823.1 - 1.8e-18 65.6 2.2 0.0034 18.1 0.0 6.5 1 1 5 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 EKX32823.1 - 6.9e-16 57.1 1.0 0.0061 16.7 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX32823.1 - 1e-14 54.9 1.2 0.00035 21.2 0.0 4.2 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 EKX32823.1 - 2.3e-13 50.5 1.0 0.00083 19.8 0.0 4.6 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 EKX32823.1 - 2.1e-11 43.0 1.1 0.11 12.7 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX32823.1 - 5.7e-10 38.6 0.2 0.29 11.0 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX32823.1 - 2.5e-07 30.3 2.1 0.23 11.6 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX32823.1 - 3.3e-07 30.5 7.1 0.027 14.7 0.1 4.5 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 EKX32823.1 - 1.1e-05 25.8 0.4 24 5.8 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 EKX32823.1 - 0.0001 21.9 0.9 0.73 9.6 0.2 5.0 5 0 0 5 5 5 1 TPR repeat TPR_15 PF13429.6 EKX32823.1 - 0.00022 20.6 0.5 1.4 8.0 0.0 3.9 2 1 2 4 4 4 1 Tetratricopeptide repeat Sel1 PF08238.12 EKX32823.1 - 0.0011 19.5 3.2 2.6 8.9 0.1 5.7 6 0 0 6 6 6 1 Sel1 repeat Coatomer_E PF04733.14 EKX32823.1 - 0.038 13.4 0.7 2.8 7.3 0.0 2.8 3 0 0 3 3 3 0 Coatomer epsilon subunit TPR_10 PF13374.6 EKX32823.1 - 0.059 13.3 4.1 11 6.0 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Alginate_exp PF13372.6 EKX32823.1 - 0.094 11.4 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Alginate export XPA_C PF05181.12 EKX32823.1 - 0.11 12.5 0.1 0.4 10.7 0.0 1.9 2 0 0 2 2 1 0 XPA protein C-terminus Sec16_C PF12931.7 EKX32823.1 - 0.16 11.6 0.0 4.3 6.9 0.0 3.0 2 1 1 3 3 3 0 Sec23-binding domain of Sec16 Ank_4 PF13637.6 EKX32825.1 - 4.9e-18 65.3 3.4 2.6e-09 37.4 0.1 5.0 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX32825.1 - 3.9e-16 59.4 0.6 9.3e-12 45.4 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX32825.1 - 1.5e-15 57.0 1.2 4.6e-06 26.8 0.2 3.5 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX32825.1 - 2.2e-12 46.0 0.5 0.00072 19.8 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EKX32825.1 - 1.1e-07 32.0 3.4 0.013 15.9 0.3 4.5 4 1 0 4 4 4 3 Ankyrin repeat LRR_8 PF13855.6 EKX32826.1 - 1.2e-16 60.2 7.3 8.5e-11 41.5 1.3 2.2 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EKX32826.1 - 1.1e-13 51.1 2.9 3.6e-09 36.7 2.7 2.3 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX32826.1 - 1.4e-05 25.0 1.6 0.28 11.9 0.1 3.3 3 0 0 3 3 3 2 Leucine Rich Repeat Ephrin_rec_like PF07699.13 EKX32826.1 - 0.0045 16.7 4.6 0.0045 16.7 4.6 3.7 2 1 1 3 3 3 2 Putative ephrin-receptor like LRR_5 PF13306.6 EKX32826.1 - 0.01 15.8 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) TNFR_c6 PF00020.18 EKX32826.1 - 0.027 14.9 10.4 0.027 14.9 10.4 3.0 2 1 1 3 3 3 0 TNFR/NGFR cysteine-rich region LRR_6 PF13516.6 EKX32826.1 - 0.055 13.6 0.5 0.055 13.6 0.5 2.8 3 0 0 3 3 3 0 Leucine Rich repeat LRR_9 PF14580.6 EKX32826.1 - 0.099 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat DDRGK PF09756.9 EKX32827.1 - 0.0051 16.4 2.7 0.0065 16.1 2.7 1.2 1 0 0 1 1 1 1 DDRGK domain Med2 PF11214.8 EKX32827.1 - 0.54 10.4 3.6 0.92 9.7 3.6 1.4 1 0 0 1 1 1 0 Mediator complex subunit 2 LRR_8 PF13855.6 EKX32828.1 - 9.5e-33 111.8 21.1 2.8e-13 49.4 0.2 3.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EKX32828.1 - 1.2e-25 89.1 38.5 8e-08 32.5 3.5 3.6 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX32828.1 - 1e-10 41.6 4.9 1.1e-07 31.8 2.1 2.1 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EKX32828.1 - 3.7e-08 32.8 12.6 0.52 11.1 0.1 6.0 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_9 PF14580.6 EKX32828.1 - 0.0023 17.4 0.1 1 8.8 0.0 2.3 1 1 2 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 EKX32828.1 - 0.29 11.3 0.3 0.29 11.3 0.3 5.1 5 0 0 5 5 5 0 Leucine Rich repeat Vps39_1 PF10366.9 EKX32829.1 - 0.086 13.1 0.0 0.093 13.0 0.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 PDZ_6 PF17820.1 EKX32830.1 - 7.1e-07 29.0 0.5 4.3e-06 26.5 0.0 2.6 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX32830.1 - 3.6e-05 24.0 0.0 0.00011 22.5 0.0 1.8 1 0 0 1 1 1 1 PDZ domain HMMR_N PF15905.5 EKX32830.1 - 0.00052 19.6 5.0 0.00052 19.6 5.0 6.3 2 2 3 5 5 5 1 Hyaluronan mediated motility receptor N-terminal PDZ PF00595.24 EKX32830.1 - 0.003 17.9 0.0 0.012 15.9 0.0 2.1 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX32830.1 - 0.042 13.8 0.1 0.11 12.4 0.1 1.8 1 0 0 1 1 1 0 Tricorn protease PDZ domain LCAT PF02450.15 EKX32832.1 - 9.9e-26 90.8 0.0 2e-24 86.5 0.0 2.0 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 EKX32832.1 - 1.7e-06 27.9 0.0 2.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 EKX32832.1 - 0.00032 20.1 0.0 0.00047 19.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Palm_thioest PF02089.15 EKX32832.1 - 0.0012 18.8 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 EKX32832.1 - 0.003 17.1 0.0 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EKX32832.1 - 0.0087 16.7 0.1 0.018 15.7 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 EKX32832.1 - 0.0097 15.4 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 EKX32832.1 - 0.014 15.0 0.1 0.029 14.0 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 EKX32832.1 - 0.041 13.7 0.0 0.068 13.0 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase His_Phos_1 PF00300.22 EKX32832.1 - 0.12 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) TPR_16 PF13432.6 EKX32834.1 - 0.071 13.8 0.0 0.37 11.5 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Beta-lactamase PF00144.24 EKX32835.1 - 2.5e-26 92.7 0.0 3.5e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Methyltransf_12 PF08242.12 EKX32836.1 - 7.9e-09 36.2 0.0 1.7e-07 31.9 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX32836.1 - 5.8e-07 30.1 0.0 1.1e-05 26.0 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX32836.1 - 2.5e-06 27.4 0.0 4.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX32836.1 - 0.00029 20.7 0.0 0.00048 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EKX32836.1 - 0.002 17.7 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EKX32836.1 - 0.0021 18.7 0.0 0.026 15.1 0.0 2.5 1 1 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.13 EKX32836.1 - 0.039 13.5 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 DUF5031 PF16434.5 EKX32836.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5031) PsbQ PF05757.11 EKX32837.1 - 0.0022 17.8 17.0 0.039 13.7 7.4 2.4 1 1 0 2 2 2 2 Oxygen evolving enhancer protein 3 (PsbQ) Borrelia_orfA PF02414.15 EKX32837.1 - 1.6 8.3 8.8 3 7.4 8.8 1.5 1 1 0 1 1 1 0 Borrelia ORF-A YlbD_coat PF14071.6 EKX32837.1 - 2.1 8.6 8.3 0.35 11.1 3.8 1.9 1 1 1 2 2 2 0 Putative coat protein Atg14 PF10186.9 EKX32837.1 - 3 6.9 8.0 4.3 6.3 8.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 EKX32838.1 - 0.018 15.3 7.8 0.018 15.3 7.8 3.4 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Trm5_N PF18093.1 EKX32838.1 - 0.034 14.0 0.1 0.11 12.4 0.1 1.9 1 0 0 1 1 1 0 tRNA methyltransferase 5 N-terminal domain CALCOCO1 PF07888.11 EKX32838.1 - 0.1 11.4 41.6 0.16 10.8 41.6 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Tet_JBP PF12851.7 EKX32838.1 - 0.12 11.7 4.1 0.12 11.7 3.0 1.3 1 1 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily DUF948 PF06103.11 EKX32838.1 - 0.77 10.1 10.2 5 7.4 0.0 3.6 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 EKX32838.1 - 4.1 7.5 25.4 0.064 13.3 1.6 3.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF1207 PF06727.11 EKX32839.1 - 0.075 11.9 0.1 0.08 11.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1207) CoaE PF01121.20 EKX32840.1 - 5.6e-50 169.5 0.0 6.6e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.6 EKX32840.1 - 0.00095 19.3 1.1 0.089 12.9 1.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EKX32840.1 - 0.024 15.2 3.5 0.41 11.2 3.5 2.3 1 1 0 1 1 1 0 AAA domain APOBEC_C PF05240.14 EKX32840.1 - 0.025 14.5 0.1 0.044 13.7 0.1 1.4 1 0 0 1 1 1 0 APOBEC-like C-terminal domain Nitro_FeMo-Co PF02579.17 EKX32840.1 - 0.068 13.5 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor Zeta_toxin PF06414.12 EKX32840.1 - 0.077 12.3 0.0 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin CTP_transf_like PF01467.26 EKX32841.1 - 6.5e-06 26.4 0.0 1.2e-05 25.6 0.0 1.5 1 1 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 EKX32841.1 - 0.09 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 FAD synthetase Abhydrolase_1 PF00561.20 EKX32842.1 - 3e-16 59.8 0.2 4.3e-16 59.3 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EKX32842.1 - 8.3e-12 46.2 3.6 1.1e-10 42.5 3.6 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EKX32842.1 - 1.6e-10 40.6 0.0 2.2e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EKX32842.1 - 3.8e-06 27.2 0.0 0.00014 22.1 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain Palm_thioest PF02089.15 EKX32842.1 - 0.00019 21.4 0.0 0.00023 21.1 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 EKX32842.1 - 0.009 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 EKX32842.1 - 0.032 13.8 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase PGAP1 PF07819.13 EKX32842.1 - 0.055 13.2 0.0 0.085 12.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.20 EKX32842.1 - 0.11 12.2 0.1 0.17 11.5 0.1 1.4 1 1 0 1 1 1 0 Putative esterase Homoserine_dh PF00742.19 EKX32843.1 - 1.6e-45 155.2 1.1 6.3e-45 153.2 0.1 2.2 2 0 0 2 2 2 1 Homoserine dehydrogenase AA_kinase PF00696.28 EKX32843.1 - 1.5e-37 129.5 2.1 2.2e-36 125.6 0.1 2.5 2 0 0 2 2 2 1 Amino acid kinase family NAD_binding_3 PF03447.16 EKX32843.1 - 7e-19 68.6 0.2 2.5e-18 66.8 0.0 2.1 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain ACT_7 PF13840.6 EKX32843.1 - 4.6e-16 58.4 2.7 5.4e-07 29.3 0.2 2.9 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 EKX32843.1 - 1.5e-12 47.0 1.1 1.5e-06 27.9 0.0 2.9 2 0 0 2 2 2 2 ACT domain DapB_N PF01113.20 EKX32843.1 - 4.1e-06 26.9 0.1 2.5e-05 24.4 0.1 2.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 EKX32843.1 - 0.00013 22.4 1.6 0.0011 19.3 0.6 3.0 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Glyco_transf_28 PF03033.20 EKX32843.1 - 0.039 14.0 0.2 0.25 11.4 0.0 2.4 2 0 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain ACT_6 PF13740.6 EKX32843.1 - 0.11 12.5 1.5 4.8 7.2 0.1 2.9 2 0 0 2 2 2 0 ACT domain DUF3886 PF13025.6 EKX32843.1 - 1.2 9.4 6.3 16 5.8 1.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) Roc PF08477.13 EKX32844.1 - 1e-13 51.6 0.0 2.8e-13 50.1 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase TIR_2 PF13676.6 EKX32844.1 - 1.3e-12 48.4 0.0 4.5e-09 36.9 0.0 2.7 2 0 0 2 2 2 2 TIR domain COR PF16095.5 EKX32844.1 - 6.7e-07 29.3 0.0 0.023 14.5 0.0 4.3 4 0 0 4 4 4 2 C-terminal of Roc, COR, domain Arf PF00025.21 EKX32844.1 - 0.00018 21.0 0.0 0.00039 19.9 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EKX32844.1 - 0.002 17.8 0.0 0.004 16.8 0.0 1.5 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EKX32844.1 - 0.021 14.9 0.0 0.16 12.0 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase UPF0560 PF10577.9 EKX32844.1 - 0.58 8.6 2.2 0.87 8.0 2.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 IMUP PF15761.5 EKX32845.1 - 0.92 10.2 9.8 0.95 10.2 1.6 2.7 2 1 0 2 2 2 0 Immortalisation up-regulated protein Myb_DNA-binding PF00249.31 EKX32847.1 - 1.6e-06 28.2 0.0 4.2e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain RRM_1 PF00076.22 EKX32848.1 - 6.1e-28 96.5 0.0 1.4e-15 56.8 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EKX32848.1 - 0.00084 19.4 0.1 0.32 11.1 0.0 2.5 2 0 0 2 2 2 2 Limkain b1 RRM_7 PF16367.5 EKX32848.1 - 0.047 13.8 0.0 0.23 11.6 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif Nup35_RRM_2 PF14605.6 EKX32848.1 - 0.048 13.7 0.1 1.4 9.0 0.0 2.7 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif LAL_C2 PF18603.1 EKX32848.1 - 0.13 12.4 0.0 0.13 12.4 0.0 3.5 4 0 0 4 4 4 0 L-amino acid ligase C-terminal domain 2 AP2 PF00847.20 EKX32848.1 - 0.62 10.3 0.1 0.62 10.3 0.1 2.5 2 0 0 2 2 2 0 AP2 domain IQ PF00612.27 EKX32849.1 - 4.9 7.2 10.9 0.22 11.4 0.1 3.9 4 0 0 4 4 4 0 IQ calmodulin-binding motif DUF4033 PF13225.6 EKX32851.1 - 1e-33 115.1 0.2 1.5e-33 114.6 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4033) RWP-RK PF02042.15 EKX32852.1 - 4.5e-06 26.5 0.4 9.4e-06 25.5 0.4 1.5 1 0 0 1 1 1 1 RWP-RK domain MSA-2c PF12238.8 EKX32853.1 - 0.27 11.2 3.0 0.33 10.9 3.0 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c RWP-RK PF02042.15 EKX32854.1 - 3.7e-16 58.8 0.1 7.9e-16 57.8 0.1 1.5 1 0 0 1 1 1 1 RWP-RK domain DUF2431 PF10354.9 EKX32855.1 - 5.1e-34 118.0 0.0 8.5e-16 58.7 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF2431) ART PF01129.18 EKX32856.1 - 7.3e-05 22.2 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase ADPrib_exo_Tox PF03496.14 EKX32856.1 - 0.001 18.5 0.1 0.085 12.2 0.1 2.2 1 1 0 1 1 1 1 ADP-ribosyltransferase exoenzyme Lectin_C PF00059.21 EKX32857.1 - 0.028 15.2 1.9 0.33 11.7 0.1 2.8 2 1 1 3 3 3 0 Lectin C-type domain Myb_DNA-binding PF00249.31 EKX32860.1 - 2.9e-05 24.1 0.1 0.00017 21.7 0.1 2.2 1 1 0 1 1 1 1 Myb-like DNA-binding domain DUF1722 PF08349.11 EKX32860.1 - 0.022 15.1 0.1 0.24 11.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Nop14 PF04147.12 EKX32861.1 - 0.00063 18.1 5.1 0.00071 17.9 5.1 1.0 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 EKX32861.1 - 0.019 13.3 8.3 0.021 13.1 8.3 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4834 PF16118.5 EKX32861.1 - 0.037 15.0 0.2 0.2 12.7 0.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) SpoIIIAH PF12685.7 EKX32861.1 - 0.12 12.2 1.7 0.14 12.0 1.4 1.4 1 1 0 1 1 1 0 SpoIIIAH-like protein DUF2457 PF10446.9 EKX32861.1 - 0.3 10.2 24.3 0.35 9.9 24.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) YL1 PF05764.13 EKX32861.1 - 0.34 11.0 8.4 0.41 10.7 8.4 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DNA_pol_phi PF04931.13 EKX32861.1 - 0.64 8.0 16.1 0.76 7.8 16.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Utp14 PF04615.13 EKX32861.1 - 1.2 7.6 8.9 1.5 7.3 8.9 1.2 1 0 0 1 1 1 0 Utp14 protein RRN3 PF05327.11 EKX32861.1 - 1.8 7.0 6.7 1.9 6.9 6.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 eIF-3c_N PF05470.12 EKX32861.1 - 2.7 6.2 5.0 3.3 5.9 5.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SDA1 PF05285.12 EKX32861.1 - 2.9 7.2 11.5 3.6 6.9 11.5 1.2 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 EKX32861.1 - 5 6.8 23.8 4.8 6.8 17.9 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF2722 PF10846.8 EKX32861.1 - 5.2 5.9 6.4 6.2 5.6 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RNA_pol_3_Rpc31 PF11705.8 EKX32861.1 - 8.7 6.5 20.3 1.3 9.2 15.9 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 MSP1_C PF07462.11 EKX32861.1 - 9.1 4.8 6.6 12 4.5 6.6 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus HMG-CoA_red PF00368.18 EKX32862.1 - 1.1e-50 172.7 1.1 1.1e-50 172.7 1.1 1.5 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase TFIIA PF03153.13 EKX32862.1 - 2.2e-06 27.9 21.0 2.2e-06 27.9 21.0 1.8 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit CobT PF06213.12 EKX32862.1 - 0.0013 18.2 13.2 0.0023 17.4 13.2 1.5 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT CCDC53 PF10152.9 EKX32862.1 - 0.0078 16.6 7.8 0.013 15.9 7.8 1.4 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex DDHD PF02862.17 EKX32862.1 - 0.021 15.0 7.6 0.038 14.1 7.6 1.4 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.16 EKX32862.1 - 0.039 14.0 3.1 0.061 13.4 3.1 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4834 PF16118.5 EKX32862.1 - 0.058 14.4 13.1 0.13 13.2 13.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) AAA_23 PF13476.6 EKX32862.1 - 0.059 13.9 15.1 0.071 13.6 14.2 1.6 2 0 0 2 2 1 0 AAA domain Orf78 PF06024.12 EKX32862.1 - 0.088 13.1 8.2 0.17 12.2 8.2 1.4 1 0 0 1 1 1 0 Orf78 (ac78) SID-1_RNA_chan PF13965.6 EKX32862.1 - 0.1 11.0 0.2 0.088 11.2 0.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CPSF100_C PF13299.6 EKX32862.1 - 0.11 12.7 8.7 0.2 11.9 8.7 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 EKX32862.1 - 0.17 11.7 9.8 0.25 11.2 9.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Suf PF05843.14 EKX32862.1 - 0.18 11.7 15.0 0.33 10.9 15.0 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MMU163 PF17119.5 EKX32862.1 - 0.29 10.2 8.1 0.5 9.5 8.1 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis SprA-related PF12118.8 EKX32862.1 - 0.32 10.1 25.4 0.52 9.4 25.4 1.4 1 0 0 1 1 1 0 SprA-related family EOS1 PF12326.8 EKX32862.1 - 0.34 10.8 4.6 0.54 10.2 4.6 1.3 1 0 0 1 1 1 0 N-glycosylation protein DUF778 PF05608.12 EKX32862.1 - 0.47 10.8 4.5 0.73 10.2 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF778) Baculo_PP31 PF05311.11 EKX32862.1 - 0.69 9.3 12.0 0.99 8.8 12.0 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) SpoIIP PF07454.11 EKX32862.1 - 1.4 8.3 16.7 2.3 7.6 16.7 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Hid1 PF12722.7 EKX32862.1 - 1.5 6.9 10.4 1.7 6.6 10.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM60A PF15396.6 EKX32862.1 - 1.7 8.6 9.9 2.8 7.9 9.9 1.4 1 0 0 1 1 1 0 Protein Family FAM60A FixO PF02433.15 EKX32862.1 - 2.1 7.8 11.1 3.2 7.1 11.1 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO Presenilin PF01080.17 EKX32862.1 - 2.3 6.9 17.1 3.4 6.3 17.1 1.2 1 0 0 1 1 1 0 Presenilin PIP5K PF01504.18 EKX32862.1 - 3.4 6.8 11.2 4.6 6.4 11.2 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase STAC2_u1 PF16664.5 EKX32862.1 - 4.6 7.7 10.9 2.2 8.8 6.8 2.2 2 0 0 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 eIF-3_zeta PF05091.12 EKX32862.1 - 6.9 5.5 22.4 9.9 5.0 22.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Coilin_N PF15862.5 EKX32862.1 - 7 6.4 17.6 12 5.7 17.6 1.4 1 0 0 1 1 1 0 Coilin N-terminus Peroxin-13_N PF04088.13 EKX32862.1 - 8.2 6.7 10.7 1.6 9.0 5.8 2.3 3 0 0 3 3 3 0 Peroxin 13, N-terminal region TERB2 PF15101.6 EKX32862.1 - 9 6.3 26.3 15 5.6 26.3 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF775 PF05603.12 EKX32862.1 - 9.9 5.6 17.6 18 4.8 17.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Multi_Drug_Res PF00893.19 EKX32863.1 - 8.6e-24 84.0 8.8 1.1e-23 83.7 8.8 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 EKX32863.1 - 0.00014 22.0 12.2 0.00018 21.7 12.2 1.2 1 0 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 EKX32863.1 - 0.0077 16.3 1.8 0.0094 16.0 1.5 1.3 1 1 0 1 1 1 1 Putative transmembrane family 234 TMEM100 PF16311.5 EKX32863.1 - 0.15 11.7 2.8 0.23 11.1 0.2 2.0 2 0 0 2 2 2 0 Transmembrane protein 100 Dor1 PF04124.12 EKX32864.1 - 2e-76 256.9 4.1 2.4e-76 256.6 4.1 1.1 1 0 0 1 1 1 1 Dor1-like family DUF4795 PF16043.5 EKX32864.1 - 0.0077 15.9 0.6 0.016 14.9 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) Zip PF02535.22 EKX32865.1 - 2.3 7.4 4.0 4.3 6.5 4.0 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1480 PF07351.13 EKX32866.1 - 0.16 12.2 10.1 1.8 8.9 2.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1480) DUF3332 PF11810.8 EKX32866.1 - 0.19 11.4 0.2 0.25 11.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) BRE1 PF08647.11 EKX32867.1 - 0.0024 17.9 0.6 0.0024 17.9 0.6 3.1 3 0 0 3 3 3 1 BRE1 E3 ubiquitin ligase DUF1593 PF07632.11 EKX32867.1 - 0.0078 15.7 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) ATG16 PF08614.11 EKX32867.1 - 0.012 15.8 25.4 0.26 11.5 2.1 2.6 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 EKX32867.1 - 0.014 15.3 21.3 0.037 13.8 0.8 2.6 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH YabA PF06156.13 EKX32867.1 - 0.027 15.1 12.2 1.9 9.2 1.5 3.3 3 0 0 3 3 3 0 Initiation control protein YabA Csm1_N PF18504.1 EKX32867.1 - 0.053 13.9 1.5 0.053 13.9 1.5 3.7 3 1 1 4 4 4 0 Csm1 N-terminal domain SlyX PF04102.12 EKX32867.1 - 0.061 14.0 0.3 0.061 14.0 0.3 3.5 3 1 0 3 3 3 0 SlyX HrpB7 PF09486.10 EKX32867.1 - 0.14 12.6 17.7 0.46 10.9 0.2 2.7 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) HALZ PF02183.18 EKX32867.1 - 0.15 12.3 0.4 0.15 12.3 0.4 3.9 4 0 0 4 4 4 0 Homeobox associated leucine zipper Spc7 PF08317.11 EKX32867.1 - 0.17 10.8 21.1 0.12 11.3 1.0 2.5 2 1 1 3 3 3 0 Spc7 kinetochore protein DivIC PF04977.15 EKX32867.1 - 0.17 11.6 16.5 0.16 11.7 3.0 3.4 3 0 0 3 3 3 0 Septum formation initiator Atg14 PF10186.9 EKX32867.1 - 0.31 10.1 17.8 0.33 10.0 2.2 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sec2p PF06428.11 EKX32867.1 - 0.47 10.5 10.5 1 9.4 1.2 3.1 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p KxDL PF10241.9 EKX32867.1 - 0.47 10.8 9.8 2.8 8.3 0.3 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein Swi5 PF07061.11 EKX32867.1 - 0.65 10.1 6.9 2.9 8.0 0.1 3.0 3 0 0 3 3 3 0 Swi5 TMEM132D_N PF15705.5 EKX32867.1 - 0.7 9.7 2.9 7.5 6.4 0.2 3.0 2 1 1 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term Fez1 PF06818.15 EKX32867.1 - 0.92 9.9 22.0 1.3 9.4 9.0 2.2 1 1 1 2 2 2 0 Fez1 ZapB PF06005.12 EKX32867.1 - 1.9 9.0 27.8 0.2 12.1 1.9 4.1 2 2 1 3 3 3 0 Cell division protein ZapB CC2-LZ PF16516.5 EKX32867.1 - 2.6 8.5 12.9 0.4 11.1 0.7 2.8 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator PRKG1_interact PF15898.5 EKX32867.1 - 3.5 8.6 26.7 1.6 9.7 3.6 3.4 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain CENP-H PF05837.12 EKX32867.1 - 5.5 7.4 22.1 0.17 12.3 5.1 3.3 2 2 1 3 3 3 0 Centromere protein H (CENP-H) Fib_alpha PF08702.10 EKX32867.1 - 5.8 7.1 7.1 1.5 9.0 0.4 2.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF2205 PF10224.9 EKX32867.1 - 6.1 6.9 14.0 4.3 7.4 2.3 3.3 3 0 0 3 3 3 0 Short coiled-coil protein Cep57_CLD_2 PF14197.6 EKX32867.1 - 6.3 7.0 23.5 6.9 6.8 6.0 3.7 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 PKcGMP_CC PF16808.5 EKX32867.1 - 7.4 6.5 14.1 0.42 10.5 5.7 3.1 2 1 1 3 3 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Bac_rhodopsin PF01036.18 EKX32869.1 - 3.5e-18 66.0 3.5 6.8e-10 38.9 0.1 2.2 1 1 1 2 2 2 2 Bacteriorhodopsin-like protein zf-C3HC4_3 PF13920.6 EKX32870.1 - 0.0091 15.8 7.2 0.018 14.9 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX32870.1 - 0.37 10.8 9.9 0.83 9.7 9.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 EKX32870.1 - 0.42 10.5 10.5 0.86 9.5 10.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RNA_POL_M_15KD PF02150.16 EKX32870.1 - 1.4 8.8 9.7 0.092 12.6 4.3 1.8 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-C3HC4_2 PF13923.6 EKX32870.1 - 1.9 8.4 11.2 3.9 7.4 11.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX32870.1 - 3.3 7.8 8.6 4.5 7.4 7.1 2.1 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 EKX32870.1 - 3.4 8.1 10.2 9.2 6.7 10.2 1.8 1 0 0 1 1 1 0 Ring finger domain DUF1263 PF06882.12 EKX32871.1 - 0.19 11.8 0.0 0.44 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1263) Cnn_1N PF07989.11 EKX32871.1 - 0.55 10.4 5.6 3.8 7.7 0.0 3.4 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 MlaA PF04333.13 EKX32872.1 - 0.033 13.9 0.1 0.039 13.6 0.1 1.1 1 0 0 1 1 1 0 MlaA lipoprotein Mobilization_B PF17511.2 EKX32872.1 - 0.067 13.6 0.1 0.068 13.5 0.1 1.1 1 0 0 1 1 1 0 Mobilization protein B AP2 PF00847.20 EKX32872.1 - 0.36 11.1 7.1 0.51 10.6 0.4 2.1 1 1 1 2 2 2 0 AP2 domain Pkinase_Tyr PF07714.17 EKX32873.1 - 7.9e-14 51.6 0.0 8.6e-14 51.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX32873.1 - 5.1e-11 42.4 0.0 6e-11 42.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain DNA_pol_A_exoN PF18305.1 EKX32873.1 - 0.0047 17.2 0.1 0.0054 17.0 0.1 1.1 1 0 0 1 1 1 1 3' to 5' exonuclease C-terminal domain DUF4129 PF13559.6 EKX32873.1 - 0.055 13.7 0.8 0.082 13.2 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) Trypan_PARP PF05887.11 EKX32874.1 - 0.1 12.6 62.9 8.8 6.3 22.8 3.0 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) Med6 PF04934.14 EKX32875.1 - 3.2e-13 49.6 0.0 5e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component DUF5355 PF17306.2 EKX32875.1 - 0.013 14.5 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5355) UCR_TM PF02921.14 EKX32875.1 - 0.14 12.7 0.2 0.55 10.8 0.0 2.1 2 1 0 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region DUF4535 PF15054.6 EKX32875.1 - 0.18 11.6 0.7 2.4 8.0 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4535) WD40 PF00400.32 EKX32876.1 - 7.5e-31 105.7 14.4 1.9e-05 25.3 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX32876.1 - 0.00024 21.3 0.3 2.8 8.3 0.0 4.6 5 1 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX32876.1 - 0.012 14.6 0.0 5.9 5.7 0.0 4.0 3 1 2 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_12 PF13087.6 EKX32877.1 - 3.8e-48 163.7 0.0 4.6e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EKX32877.1 - 2.1e-09 37.6 0.0 5.3e-09 36.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EKX32877.1 - 0.003 17.3 0.0 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EKX32877.1 - 0.019 14.7 0.0 0.45 10.2 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Arm PF00514.23 EKX32878.1 - 2.5e-21 74.9 25.0 9.6e-07 28.6 0.2 8.5 10 0 0 10 10 10 6 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EKX32878.1 - 3.8e-07 30.0 5.5 0.00038 20.4 0.7 4.3 3 1 1 4 4 4 2 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 EKX32878.1 - 0.0014 19.0 2.0 1.5 9.3 0.2 3.7 2 2 1 3 3 3 1 HEAT repeats V-ATPase_H_C PF11698.8 EKX32878.1 - 0.019 15.1 0.1 3.9 7.6 0.0 3.3 3 0 0 3 3 3 0 V-ATPase subunit H HEAT PF02985.22 EKX32878.1 - 0.13 12.6 2.6 31 5.2 0.1 4.5 4 0 0 4 4 4 0 HEAT repeat DUF4704 PF15787.5 EKX32878.1 - 0.33 10.1 4.7 0.35 10.1 0.2 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4704) LRR_6 PF13516.6 EKX32880.1 - 2.7e-12 45.7 11.7 6.2e-05 22.7 0.4 4.2 4 0 0 4 4 4 3 Leucine Rich repeat LRR_1 PF00560.33 EKX32880.1 - 0.097 13.3 5.8 8.1 7.4 0.0 3.8 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.7 EKX32880.1 - 0.12 12.9 5.3 7 7.2 2.8 2.9 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) MutS_I PF01624.20 EKX32881.1 - 1.3e-27 96.3 0.1 3e-27 95.1 0.1 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EKX32881.1 - 3.6e-15 56.5 0.8 1.1e-14 54.9 0.0 2.2 2 0 0 2 2 2 1 MutS domain II LicD PF04991.13 EKX32881.1 - 0.063 13.4 5.5 0.12 12.5 5.5 1.4 1 0 0 1 1 1 0 LicD family AAA PF00004.29 EKX32882.1 - 3.6e-77 257.1 0.0 6.1e-34 117.3 0.0 3.5 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EKX32882.1 - 4.9e-17 61.5 4.2 3.9e-09 36.2 0.1 3.2 3 0 0 3 3 3 2 AAA+ lid domain RuvB_N PF05496.12 EKX32882.1 - 1.8e-09 37.6 0.0 0.00025 20.8 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EKX32882.1 - 3.5e-09 36.8 0.2 0.0019 18.2 0.0 4.0 4 1 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EKX32882.1 - 7.6e-08 32.7 0.0 0.011 15.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EKX32882.1 - 6e-07 29.7 0.0 0.0041 17.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 EKX32882.1 - 4.7e-06 27.1 9.6 0.0068 16.8 0.6 4.6 2 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 EKX32882.1 - 4.2e-05 23.8 1.4 0.21 11.9 0.1 4.3 2 2 2 4 4 4 1 AAA domain TsaE PF02367.17 EKX32882.1 - 4.5e-05 23.4 0.0 0.011 15.7 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 EKX32882.1 - 7e-05 22.3 0.7 0.42 10.0 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EKX32882.1 - 7.4e-05 23.1 0.1 1.1 9.7 0.0 3.5 4 0 0 4 4 2 2 RNA helicase IstB_IS21 PF01695.17 EKX32882.1 - 0.0002 21.1 0.0 0.59 9.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Rad17 PF03215.15 EKX32882.1 - 0.00022 21.2 0.0 0.082 12.8 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain TIP49 PF06068.13 EKX32882.1 - 0.00026 20.3 0.0 0.16 11.2 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_28 PF13521.6 EKX32882.1 - 0.00027 21.2 1.1 0.42 10.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain ATPase PF06745.13 EKX32882.1 - 0.00074 18.9 0.0 3.5 6.9 0.0 3.4 3 0 0 3 3 3 1 KaiC AAA_25 PF13481.6 EKX32882.1 - 0.0014 18.3 0.1 2.7 7.5 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_14 PF13173.6 EKX32882.1 - 0.0017 18.4 0.0 3.3 7.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 EKX32882.1 - 0.0018 18.1 0.0 1.9 8.3 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EKX32882.1 - 0.0027 17.2 0.0 0.62 9.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 EKX32882.1 - 0.0076 16.0 0.0 0.47 10.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EKX32882.1 - 0.013 16.0 0.4 3.5 8.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.13 EKX32882.1 - 0.022 14.0 0.0 2.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_11 PF13086.6 EKX32882.1 - 0.033 14.0 5.4 1.3 8.7 0.0 4.0 3 1 1 4 4 4 0 AAA domain AAA_19 PF13245.6 EKX32882.1 - 0.042 14.2 0.3 0.24 11.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 EKX32882.1 - 0.061 13.4 0.0 2.6 8.2 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 EKX32882.1 - 0.073 12.1 0.0 3.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AFG1_ATPase PF03969.16 EKX32882.1 - 0.086 11.7 0.0 0.32 9.8 0.0 1.8 2 0 0 2 2 2 0 AFG1-like ATPase ABC_tran PF00005.27 EKX32882.1 - 0.099 13.2 0.0 15 6.1 0.0 2.8 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.12 EKX32882.1 - 0.12 12.3 0.4 13 5.6 0.1 2.9 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.26 EKX32882.1 - 0.14 11.8 0.0 33 4.2 0.0 3.2 2 1 0 2 2 2 0 Sigma-54 interaction domain ATPase_2 PF01637.18 EKX32882.1 - 0.51 10.2 2.4 51 3.7 0.0 3.7 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea Ion_trans PF00520.31 EKX32883.1 - 7.4e-35 120.3 28.2 1.3e-34 119.6 28.2 1.4 1 0 0 1 1 1 1 Ion transport protein PH PF00169.29 EKX32883.1 - 2.3e-06 28.0 0.0 5.1e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 PH domain PKD_channel PF08016.12 EKX32883.1 - 3.6e-05 22.6 18.3 0.00043 19.1 10.0 2.3 1 1 1 2 2 2 2 Polycystin cation channel EF-hand_1 PF00036.32 EKX32883.1 - 0.00098 18.5 0.1 0.0026 17.2 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EKX32883.1 - 0.0016 18.2 0.1 0.0055 16.5 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain PIG-F PF06699.11 EKX32883.1 - 1.1 9.4 5.4 0.23 11.6 1.8 1.7 2 0 0 2 2 2 0 GPI biosynthesis protein family Pig-F G0-G1_switch_2 PF15103.6 EKX32884.1 - 0.13 12.7 0.3 0.13 12.7 0.3 1.8 2 0 0 2 2 2 0 G0/G1 switch protein 2 DUF4539 PF15072.6 EKX32885.1 - 1.7e-15 56.8 0.1 2.6e-15 56.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) PDZ PF00595.24 EKX32887.1 - 0.00037 20.8 0.1 0.0008 19.7 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX32887.1 - 0.00089 19.0 0.9 0.024 14.5 0.5 2.6 2 0 0 2 2 2 1 PDZ domain ATPase PF06745.13 EKX32888.1 - 0.0017 17.8 0.1 0.0023 17.3 0.1 1.1 1 0 0 1 1 1 1 KaiC SRP54 PF00448.22 EKX32888.1 - 0.0025 17.5 0.2 0.0034 17.0 0.2 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain T2SSE PF00437.20 EKX32888.1 - 0.0031 16.6 0.0 0.0047 16.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 EKX32888.1 - 0.0034 17.9 0.0 0.0045 17.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 EKX32888.1 - 0.0044 17.3 0.0 0.0056 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EKX32888.1 - 0.0055 16.4 0.1 0.0079 15.9 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EKX32888.1 - 0.0075 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region PhoH PF02562.16 EKX32888.1 - 0.013 15.0 0.1 0.018 14.5 0.1 1.3 1 1 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 EKX32888.1 - 0.013 15.9 0.0 0.016 15.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 EKX32888.1 - 0.016 14.1 0.1 0.024 13.6 0.1 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_19 PF13245.6 EKX32888.1 - 0.021 15.2 0.4 0.036 14.4 0.4 1.4 1 1 0 1 1 1 0 AAA domain 2C_adapt PF08793.10 EKX32888.1 - 0.022 15.0 0.0 0.046 13.9 0.0 1.5 1 0 0 1 1 1 0 2-cysteine adaptor domain AAA_23 PF13476.6 EKX32888.1 - 0.025 15.1 0.0 0.031 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EKX32888.1 - 0.034 14.1 0.0 0.056 13.5 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 EKX32888.1 - 0.035 13.8 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain DEAD PF00270.29 EKX32888.1 - 0.046 13.5 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase RsgA_GTPase PF03193.16 EKX32888.1 - 0.063 13.2 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 EKX32888.1 - 0.076 12.3 0.2 0.21 10.8 0.0 1.7 1 1 1 2 2 2 0 Zeta toxin AAA_24 PF13479.6 EKX32888.1 - 0.084 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Myosin_head PF00063.21 EKX32888.1 - 0.17 10.1 0.0 0.2 9.8 0.0 1.0 1 0 0 1 1 1 0 Myosin head (motor domain) HA2 PF04408.23 EKX32889.1 - 1.6e-25 89.5 0.1 3e-25 88.6 0.1 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EKX32889.1 - 3e-21 75.6 0.0 1.2e-20 73.6 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EKX32889.1 - 1.2e-10 41.7 0.0 2.3e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EKX32889.1 - 0.0027 17.5 0.1 0.0062 16.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase TIP41 PF04176.13 EKX32890.1 - 7.4e-22 77.6 1.1 7.9e-22 77.5 1.1 1.0 1 0 0 1 1 1 1 TIP41-like family Robl_LC7 PF03259.17 EKX32893.1 - 0.02 14.7 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Roadblock/LC7 domain RPS31 PF17067.5 EKX32893.1 - 0.038 14.2 0.1 0.061 13.5 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S31e Ham1p_like PF01725.16 EKX32894.1 - 3e-54 183.8 0.0 3.4e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Abhydrolase_6 PF12697.7 EKX32895.1 - 1.9e-05 25.4 0.8 2.3e-05 25.1 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EKX32895.1 - 0.00027 21.2 0.1 0.00067 19.8 0.1 1.7 1 1 1 2 2 2 1 Thioesterase domain Abhydrolase_1 PF00561.20 EKX32895.1 - 0.0036 17.0 0.1 0.54 9.9 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EKX32895.1 - 0.0062 15.8 0.0 1.7 7.9 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EKX32895.1 - 0.027 14.3 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_C2 PF00648.21 EKX32896.1 - 3.1e-68 230.0 0.0 4.3e-68 229.5 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 EKX32896.1 - 0.0024 18.1 0.0 0.0059 16.9 0.0 1.7 1 1 0 1 1 1 1 Calpain large subunit, domain III DARPP-32 PF05395.12 EKX32896.1 - 0.29 11.3 7.8 0.52 10.5 7.8 1.3 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 VAD1-2 PF15310.6 EKX32896.1 - 0.37 10.6 4.5 0.64 9.9 4.5 1.3 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling CdiI_2 PF18593.1 EKX32896.1 - 0.47 11.1 2.9 1.1 10.0 2.9 1.6 1 0 0 1 1 1 0 CdiI immunity protein 3Beta_HSD PF01073.19 EKX32897.1 - 1.6e-26 93.0 0.0 2e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EKX32897.1 - 5.1e-19 68.7 0.0 6.6e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EKX32897.1 - 3.4e-10 40.1 0.0 4.6e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EKX32897.1 - 1.9e-08 34.1 0.0 4e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EKX32897.1 - 1.6e-07 30.8 0.0 2.3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 EKX32897.1 - 4.2e-06 26.1 0.0 6.4e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EKX32897.1 - 0.0022 17.6 0.0 0.0056 16.3 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 EKX32897.1 - 0.0041 16.3 0.0 0.0057 15.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain PDZ_6 PF17820.1 EKX32898.1 - 1.4e-06 28.1 0.6 8.6e-06 25.5 0.6 2.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX32898.1 - 8.2e-05 22.8 0.1 0.00021 21.5 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX32898.1 - 0.0005 20.4 0.1 0.002 18.4 0.1 2.1 1 0 0 1 1 1 1 PDZ domain Fez1 PF06818.15 EKX32898.1 - 0.0012 19.3 27.5 0.023 15.2 9.9 2.3 2 0 0 2 2 2 2 Fez1 Csd3_N PF18059.1 EKX32898.1 - 0.17 12.4 0.8 0.64 10.6 0.8 2.0 1 0 0 1 1 1 0 Csd3 N-terminal Taxilin PF09728.9 EKX32898.1 - 1.5 7.9 36.1 0.54 9.4 22.6 2.5 3 0 0 3 3 3 0 Myosin-like coiled-coil protein CENP-F_leu_zip PF10473.9 EKX32898.1 - 9.2 6.3 45.4 0.19 11.7 23.5 3.4 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LysM PF01476.20 EKX32899.1 - 0.075 13.1 0.0 0.75 9.9 0.0 2.4 2 0 0 2 2 2 0 LysM domain HSF_DNA-bind PF00447.17 EKX32901.1 - 2.2e-26 92.3 0.0 2.3e-26 92.2 0.0 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding NCD3G PF07562.14 EKX32902.1 - 2.9e-08 33.5 43.7 0.00034 20.5 6.4 4.5 3 2 1 4 4 4 3 Nine Cysteines Domain of family 3 GPCR RANK_CRD_2 PF18278.1 EKX32902.1 - 2e-06 27.8 10.0 0.19 11.9 0.4 3.8 3 0 0 3 3 3 3 Receptor activator of the NF-KB cysteine-rich repeat domain 2 Ephrin_rec_like PF07699.13 EKX32902.1 - 7.1e-05 22.5 57.4 0.041 13.6 9.9 6.0 2 1 4 6 6 6 5 Putative ephrin-receptor like hEGF PF12661.7 EKX32902.1 - 0.025 15.2 8.3 7.3 7.4 0.1 4.9 4 0 0 4 4 4 0 Human growth factor-like EGF PDZ_assoc PF10600.9 EKX32902.1 - 0.041 14.7 1.9 8 7.4 0.2 2.5 2 0 0 2 2 2 0 PDZ-associated domain of NMDA receptors Rib PF08428.10 EKX32902.1 - 0.067 13.2 0.9 5.4 7.1 0.0 3.0 1 1 2 3 3 3 0 Rib/alpha-like repeat Pro_racemase PF05544.11 EKX32902.1 - 2.5 7.1 4.1 14 4.6 0.2 2.4 1 1 2 3 3 3 0 Proline racemase HUN PF08729.10 EKX32903.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 HPC2 and ubinuclein domain Nop14 PF04147.12 EKX32904.1 - 6.7 4.8 9.1 9.3 4.3 9.1 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 EKX32905.1 - 0.09 12.6 1.4 0.12 12.2 1.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein HALZ PF02183.18 EKX32906.1 - 1.6e-06 28.2 7.5 1.1e-05 25.5 0.3 3.2 3 0 0 3 3 3 1 Homeobox associated leucine zipper DivIC PF04977.15 EKX32906.1 - 7e-05 22.5 6.7 0.035 13.9 1.0 3.3 2 1 1 3 3 3 3 Septum formation initiator Tropomyosin PF00261.20 EKX32906.1 - 7.8e-05 22.2 3.2 0.0018 17.7 0.1 2.1 2 0 0 2 2 2 1 Tropomyosin Tropomyosin_1 PF12718.7 EKX32906.1 - 0.00016 21.8 7.6 0.0028 17.8 0.3 2.5 2 1 0 2 2 2 1 Tropomyosin like Tektin PF03148.14 EKX32906.1 - 0.00085 18.2 3.4 0.013 14.3 0.3 2.3 2 0 0 2 2 2 1 Tektin family GAS PF13851.6 EKX32906.1 - 0.0011 18.3 4.4 0.013 14.9 0.8 2.2 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Uso1_p115_C PF04871.13 EKX32906.1 - 0.0015 18.9 2.0 1.6 9.1 0.3 2.4 2 1 0 2 2 2 2 Uso1 / p115 like vesicle tethering protein, C terminal region Tup_N PF08581.10 EKX32906.1 - 0.0015 18.8 1.6 0.0015 18.8 1.6 2.8 3 1 0 3 3 2 1 Tup N-terminal BST2 PF16716.5 EKX32906.1 - 0.0016 19.0 5.0 0.015 15.8 0.4 2.5 2 0 0 2 2 2 1 Bone marrow stromal antigen 2 Spc7 PF08317.11 EKX32906.1 - 0.0021 17.0 0.3 0.0021 17.0 0.3 2.1 1 1 0 2 2 2 1 Spc7 kinetochore protein DnaJ PF00226.31 EKX32906.1 - 0.003 17.7 0.7 0.033 14.3 0.1 2.8 2 1 1 3 3 2 1 DnaJ domain Rop-like PF05082.13 EKX32906.1 - 0.003 17.3 0.7 0.013 15.3 0.1 2.1 2 0 0 2 2 2 1 Rop-like WEMBL PF05701.11 EKX32906.1 - 0.0031 16.3 0.6 0.49 9.0 0.2 2.1 2 0 0 2 2 2 1 Weak chloroplast movement under blue light Fez1 PF06818.15 EKX32906.1 - 0.0032 17.9 5.8 0.059 13.8 1.2 2.3 1 1 1 2 2 2 1 Fez1 HrpB7 PF09486.10 EKX32906.1 - 0.0044 17.4 4.6 0.053 13.9 0.1 2.3 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB7) TPR_MLP1_2 PF07926.12 EKX32906.1 - 0.0056 16.7 4.6 0.46 10.6 0.1 2.7 2 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 EKX32906.1 - 0.0061 16.6 2.0 0.031 14.3 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) ATG16 PF08614.11 EKX32906.1 - 0.0067 16.7 1.0 0.0067 16.7 1.0 2.2 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 EKX32906.1 - 0.0072 16.3 0.5 0.0072 16.3 0.5 2.2 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1640 PF07798.11 EKX32906.1 - 0.0075 16.3 8.2 0.23 11.5 1.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1640) Cnn_1N PF07989.11 EKX32906.1 - 0.0095 16.1 8.6 0.025 14.7 0.8 2.6 2 1 0 2 2 2 1 Centrosomin N-terminal motif 1 Occludin_ELL PF07303.13 EKX32906.1 - 0.0095 16.6 9.0 0.079 13.7 1.7 2.4 2 0 0 2 2 2 1 Occludin homology domain Pam16 PF03656.13 EKX32906.1 - 0.015 15.3 1.4 0.041 13.9 1.4 1.7 1 1 0 1 1 1 0 Pam16 Atg14 PF10186.9 EKX32906.1 - 0.018 14.1 0.5 0.018 14.1 0.5 1.7 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 ZapB PF06005.12 EKX32906.1 - 0.02 15.3 7.1 0.03 14.8 0.2 2.5 2 1 0 2 2 2 0 Cell division protein ZapB TMPIT PF07851.13 EKX32906.1 - 0.025 13.8 0.4 0.025 13.8 0.4 1.8 2 0 0 2 2 2 0 TMPIT-like protein LMBR1 PF04791.16 EKX32906.1 - 0.026 13.5 0.7 0.031 13.2 0.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TMF_TATA_bd PF12325.8 EKX32906.1 - 0.027 14.7 4.1 0.22 11.8 0.2 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Filament PF00038.21 EKX32906.1 - 0.027 14.1 7.9 0.098 12.2 0.4 2.1 2 0 0 2 2 2 0 Intermediate filament protein Baculo_PEP_C PF04513.12 EKX32906.1 - 0.032 14.3 0.3 0.21 11.6 0.2 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PI3K_P85_iSH2 PF16454.5 EKX32906.1 - 0.038 13.6 7.7 0.079 12.5 3.0 2.5 2 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF1515 PF07439.11 EKX32906.1 - 0.039 14.0 0.4 0.039 14.0 0.4 2.0 3 0 0 3 3 1 0 Protein of unknown function (DUF1515) Seryl_tRNA_N PF02403.22 EKX32906.1 - 0.039 14.2 5.5 0.25 11.6 0.4 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain YabA PF06156.13 EKX32906.1 - 0.05 14.2 5.5 0.11 13.1 0.5 2.8 2 2 1 3 3 3 0 Initiation control protein YabA BLOC1_2 PF10046.9 EKX32906.1 - 0.054 13.8 0.6 0.054 13.8 0.6 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_DNA_bd PF12329.8 EKX32906.1 - 0.06 13.4 4.3 0.15 12.1 0.2 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4140 PF13600.6 EKX32906.1 - 0.063 13.7 3.1 3 8.3 0.1 2.7 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) IFT57 PF10498.9 EKX32906.1 - 0.067 12.2 6.5 0.94 8.4 0.9 2.4 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 LOH1CR12 PF10158.9 EKX32906.1 - 0.072 13.1 1.1 0.17 11.9 0.1 1.9 2 0 0 2 2 2 0 Tumour suppressor protein DUF5339 PF17274.2 EKX32906.1 - 0.073 13.9 2.5 0.41 11.5 0.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5339) Cortex-I_coil PF09304.10 EKX32906.1 - 0.096 12.9 0.3 0.096 12.9 0.3 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil Mod_r PF07200.13 EKX32906.1 - 0.1 12.7 7.3 0.061 13.4 1.3 2.4 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein SlyX PF04102.12 EKX32906.1 - 0.1 13.2 8.0 3.1 8.5 1.0 3.1 2 1 1 3 3 3 0 SlyX CEP63 PF17045.5 EKX32906.1 - 0.11 12.4 5.6 0.23 11.3 0.6 2.3 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa DUF745 PF05335.13 EKX32906.1 - 0.11 12.2 1.5 2 8.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) JIP_LZII PF16471.5 EKX32906.1 - 0.11 12.6 3.4 1.4 9.1 0.2 2.6 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF4472 PF14739.6 EKX32906.1 - 0.12 13.1 3.9 3.9 8.3 0.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4472) DUF2353 PF09789.9 EKX32906.1 - 0.12 11.7 8.5 1.6 8.0 0.7 2.1 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) EzrA PF06160.12 EKX32906.1 - 0.12 10.5 8.1 0.022 13.0 2.0 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF883 PF05957.13 EKX32906.1 - 0.13 12.9 2.7 10 6.8 0.3 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) FlaC_arch PF05377.11 EKX32906.1 - 0.15 12.4 2.0 20 5.7 0.1 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) CtIP_N PF10482.9 EKX32906.1 - 0.16 12.0 6.4 0.14 12.2 0.5 2.5 2 1 1 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain DUF4164 PF13747.6 EKX32906.1 - 0.17 12.2 7.6 1.7 9.0 0.7 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Laminin_II PF06009.12 EKX32906.1 - 0.2 11.7 2.4 1.6 8.7 0.3 2.3 2 0 0 2 2 2 0 Laminin Domain II SPATA1_C PF15743.5 EKX32906.1 - 0.2 11.7 6.1 4.5 7.3 1.3 2.6 2 1 0 2 2 2 0 Spermatogenesis-associated C-terminus Snapin_Pallidin PF14712.6 EKX32906.1 - 0.2 12.1 6.3 0.3 11.5 0.5 2.4 2 0 0 2 2 2 0 Snapin/Pallidin DUF724 PF05266.14 EKX32906.1 - 0.23 11.2 3.8 1.7 8.4 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) FlxA PF14282.6 EKX32906.1 - 0.25 11.3 3.2 3.8 7.5 0.3 2.4 2 0 0 2 2 2 0 FlxA-like protein Fungal_TACC PF12709.7 EKX32906.1 - 0.29 11.6 7.8 0.72 10.3 1.5 2.8 2 1 1 3 3 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins KASH_CCD PF14662.6 EKX32906.1 - 0.33 10.7 8.0 1.7 8.4 0.9 2.5 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF16 PF01519.16 EKX32906.1 - 0.37 11.3 4.5 0.46 11.0 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 bZIP_1 PF00170.21 EKX32906.1 - 0.71 10.0 5.7 0.47 10.6 0.2 2.5 2 0 0 2 2 2 0 bZIP transcription factor Rx_N PF18052.1 EKX32906.1 - 0.79 10.0 6.6 1.3 9.3 0.4 2.4 2 1 0 2 2 2 0 Rx N-terminal domain TolA_bind_tri PF16331.5 EKX32906.1 - 0.87 9.7 12.0 0.3 11.2 3.0 3.1 2 1 0 2 2 2 0 TolA binding protein trimerisation NPV_P10 PF05531.12 EKX32906.1 - 0.91 10.0 4.7 5.5 7.5 1.3 2.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein OmpH PF03938.14 EKX32906.1 - 0.94 9.8 6.4 0.94 9.8 0.1 2.4 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) BRE1 PF08647.11 EKX32906.1 - 0.95 9.6 9.6 1.2 9.3 1.4 2.7 3 0 0 3 3 2 0 BRE1 E3 ubiquitin ligase FapA PF03961.13 EKX32906.1 - 1 7.9 4.0 2.2 6.8 0.2 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A XhlA PF10779.9 EKX32906.1 - 1.1 9.6 7.6 5.9 7.2 0.1 3.2 2 1 1 3 3 3 0 Haemolysin XhlA DUF4446 PF14584.6 EKX32906.1 - 1.2 9.1 3.7 1.1 9.3 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) HalX PF08663.10 EKX32906.1 - 2.3 8.6 12.0 67 3.9 5.0 3.9 2 1 0 2 2 2 0 HalX domain Swi5 PF07061.11 EKX32906.1 - 3.3 7.8 7.3 7.5 6.7 0.7 3.2 2 1 1 3 3 3 0 Swi5 Cep57_CLD_2 PF14197.6 EKX32906.1 - 3.4 7.8 9.2 10 6.3 1.1 3.0 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Med30 PF11315.8 EKX32906.1 - 3.5 7.8 11.0 5 7.3 2.6 2.4 2 1 0 2 2 2 0 Mediator complex subunit 30 Fib_alpha PF08702.10 EKX32906.1 - 4.5 7.4 6.4 1.2 9.3 0.9 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family KxDL PF10241.9 EKX32906.1 - 4.6 7.6 8.3 0.64 10.3 1.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein CCDC-167 PF15188.6 EKX32906.1 - 6.4 7.2 12.1 9.4 6.7 0.3 3.6 2 2 1 3 3 3 0 Coiled-coil domain-containing protein 167 DUF2634 PF10934.8 EKX32907.1 - 0.14 12.3 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2634) HLH PF00010.26 EKX32911.1 - 2.3e-20 72.3 7.8 1.6e-09 37.6 0.7 3.0 3 0 0 3 3 3 2 Helix-loop-helix DNA-binding domain DUF726 PF05277.12 EKX32912.1 - 2.4e-59 201.0 0.0 2.9e-59 200.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF726) PE-PPE PF08237.11 EKX32912.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Sep15_SelM PF08806.11 EKX32913.1 - 1.6e-16 60.2 0.0 2e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Sep15/SelM redox domain Sulfotransfer_4 PF17784.1 EKX32914.1 - 2e-53 181.4 0.0 2.4e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain NESP55 PF06390.12 EKX32915.1 - 0.092 12.3 0.5 0.091 12.3 0.5 1.1 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) RWP-RK PF02042.15 EKX32916.1 - 6.9e-14 51.6 0.0 1.2e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain Pirin_C_2 PF17954.1 EKX32916.1 - 0.031 14.4 0.0 0.061 13.5 0.0 1.5 1 0 0 1 1 1 0 Quercetinase C-terminal cupin domain HTH_31 PF13560.6 EKX32916.1 - 0.07 13.5 0.1 0.21 12.0 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain ABC2_membrane PF01061.24 EKX32917.1 - 4.4e-29 101.4 15.5 4.4e-29 101.4 15.5 2.4 2 1 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EKX32917.1 - 1.7e-19 70.7 0.0 3e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EKX32917.1 - 1.4e-05 24.4 4.9 1.9e-05 24.0 4.9 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_16 PF13191.6 EKX32917.1 - 0.00011 22.7 0.0 0.00019 21.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EKX32917.1 - 0.00019 21.1 0.0 0.021 14.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EKX32917.1 - 0.00059 19.8 0.2 0.0013 18.7 0.2 1.5 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 EKX32917.1 - 0.019 15.1 0.3 0.046 13.8 0.3 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 EKX32917.1 - 0.02 14.8 0.0 0.71 9.8 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 EKX32917.1 - 0.029 14.9 0.0 0.051 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EKX32917.1 - 0.031 14.5 0.0 0.067 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 EKX32917.1 - 0.035 14.2 0.0 0.056 13.5 0.0 1.3 1 0 0 1 1 1 0 Dynamin family T2SSE PF00437.20 EKX32917.1 - 0.047 12.7 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.14 EKX32917.1 - 0.07 13.0 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.6 EKX32917.1 - 0.095 12.5 0.3 0.24 11.2 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 EKX32917.1 - 0.096 11.8 0.1 0.25 10.5 0.1 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_35 PF14516.6 EKX32917.1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain AAA_30 PF13604.6 EKX32917.1 - 0.15 11.8 0.4 1.5 8.5 0.1 2.1 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EKX32917.1 - 0.17 12.0 0.9 0.3 11.1 0.9 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain KAP_NTPase PF07693.14 EKX32917.1 - 0.18 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain PRK PF00485.18 EKX32917.1 - 0.21 11.3 0.2 0.4 10.4 0.2 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Defb50 PF17546.2 EKX32918.1 - 0.042 13.7 1.4 0.086 12.8 1.4 1.5 1 0 0 1 1 1 0 Beta defensin 50 zf-C3HC4_3 PF13920.6 EKX32919.1 - 1.3e-14 53.7 16.3 2.5e-14 52.8 16.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX32919.1 - 1.8e-06 27.7 14.7 3.5e-06 26.8 14.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EKX32919.1 - 4e-06 27.1 13.4 9e-06 25.9 13.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX32919.1 - 0.0038 17.0 14.6 0.0088 15.9 14.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Phage_tail_L PF05100.12 EKX32919.1 - 0.027 13.8 1.1 0.052 12.9 1.1 1.4 1 0 0 1 1 1 0 Phage minor tail protein L zf-RING_5 PF14634.6 EKX32919.1 - 0.1 12.6 15.8 0.22 11.5 15.8 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-P11 PF03854.14 EKX32919.1 - 6.6 6.5 13.2 27 4.5 13.2 2.0 1 1 0 1 1 1 0 P-11 zinc finger PUB PF09409.10 EKX32920.1 - 1.3e-16 60.3 0.0 1.3e-16 60.3 0.0 2.4 2 0 0 2 2 2 1 PUB domain CMS1 PF14617.6 EKX32920.1 - 5.1e-09 35.8 0.0 5.1e-09 35.8 0.0 7.5 5 1 1 7 7 7 1 U3-containing 90S pre-ribosomal complex subunit PDZ_6 PF17820.1 EKX32920.1 - 0.011 15.6 0.0 0.11 12.3 0.0 2.3 1 1 0 1 1 1 0 PDZ domain zf-C4 PF00105.18 EKX32922.1 - 0.12 12.9 1.1 0.31 11.5 1.1 1.7 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) Peripla_BP_2 PF01497.18 EKX32923.1 - 0.069 12.7 0.1 0.37 10.3 0.1 2.0 1 1 0 1 1 1 0 Periplasmic binding protein EF-hand_1 PF00036.32 EKX32927.1 - 3.2e-12 45.1 2.0 7.6e-05 22.0 0.2 3.0 2 1 1 3 3 3 2 EF hand EF-hand_6 PF13405.6 EKX32927.1 - 5.4e-10 38.4 0.5 0.00015 21.5 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EKX32927.1 - 7.1e-10 39.2 0.8 1.5e-09 38.1 0.8 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EKX32927.1 - 7.5e-06 25.7 0.9 0.031 14.1 0.3 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX32927.1 - 5.4e-05 22.5 1.4 0.18 11.3 0.3 2.9 2 1 1 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 EKX32927.1 - 0.00063 20.1 2.8 0.0007 19.9 0.4 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EKX32927.1 - 0.037 14.0 0.8 0.057 13.4 0.1 1.7 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF2666 PF10869.8 EKX32927.1 - 0.15 12.2 0.5 6.2 7.0 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) GBP PF02263.19 EKX32928.1 - 6.5e-65 219.0 0.0 9.4e-65 218.4 0.0 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 EKX32928.1 - 2.4e-18 66.6 2.4 3.4e-18 66.1 2.4 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain MMR_HSR1 PF01926.23 EKX32928.1 - 0.085 12.9 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase KapB PF08810.10 EKX32930.1 - 0.013 15.7 0.0 0.036 14.2 0.0 1.7 1 0 0 1 1 1 0 Kinase associated protein B SAM_KSR1 PF13543.6 EKX32930.1 - 0.079 13.1 0.1 0.22 11.7 0.1 1.7 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 DUF4050 PF13259.6 EKX32931.1 - 0.0071 16.7 4.1 0.024 15.0 0.1 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4050) PhoQ_Sensor PF08918.10 EKX32931.1 - 0.08 12.8 0.1 0.084 12.7 0.1 1.1 1 0 0 1 1 1 0 PhoQ Sensor Pkinase PF00069.25 EKX32932.1 - 1.6e-66 224.4 0.0 2e-66 224.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX32932.1 - 1.5e-35 122.8 0.0 2.1e-35 122.3 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX32932.1 - 8.2e-06 25.3 0.1 2.4e-05 23.8 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EKX32932.1 - 0.00022 20.3 0.4 0.00075 18.5 0.4 1.7 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EKX32932.1 - 0.0035 17.3 0.5 0.01 15.8 0.3 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX32932.1 - 0.049 12.4 0.1 0.11 11.2 0.1 1.5 1 0 0 1 1 1 0 Fungal protein kinase SET PF00856.28 EKX32933.1 - 6.1e-08 33.2 0.0 8.6e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 SET domain SASA PF03629.18 EKX32934.1 - 4.8e-29 101.6 0.0 1e-28 100.5 0.0 1.4 1 1 0 1 1 1 1 Carbohydrate esterase, sialic acid-specific acetylesterase DUF525 PF04379.14 EKX32935.1 - 1.6e-22 79.5 0.3 4.6e-22 78.1 0.1 1.8 2 0 0 2 2 2 1 ApaG domain Keratin_2_head PF16208.5 EKX32936.1 - 0.33 11.1 21.5 0.38 10.9 21.5 1.1 1 0 0 1 1 1 0 Keratin type II head KRTAP PF11759.8 EKX32936.1 - 5.4 7.7 26.6 15 6.2 26.6 1.8 1 1 0 1 1 1 0 Keratin-associated matrix TPR_17 PF13431.6 EKX32937.1 - 0.16 12.4 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Cas1_AcylT PF07779.12 EKX32938.1 - 5.1e-21 75.1 3.0 2.2e-20 73.1 3.0 1.7 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p HILPDA PF15220.6 EKX32938.1 - 0.12 12.5 0.5 1.3 9.3 0.1 2.4 2 0 0 2 2 2 0 Hypoxia-inducible lipid droplet-associated ATP_synt_H PF05493.13 EKX32938.1 - 0.78 10.2 5.5 1.5 9.3 0.3 3.1 3 0 0 3 3 3 0 ATP synthase subunit H TIG PF01833.24 EKX32939.1 - 3.5e-06 27.0 1.0 0.00074 19.5 0.1 2.2 2 0 0 2 2 2 2 IPT/TIG domain DUF5353 PF17304.2 EKX32939.1 - 0.18 11.5 1.9 3.1 7.6 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5353) TIG PF01833.24 EKX32940.1 - 3e-40 136.2 49.0 2.7e-05 24.1 0.1 13.5 13 1 0 13 13 13 12 IPT/TIG domain NiFe_hyd_SSU_C PF14720.6 EKX32940.1 - 0.028 14.8 1.4 18 5.8 0.1 3.5 2 0 0 2 2 2 0 NiFe/NiFeSe hydrogenase small subunit C-terminal SAGA-Tad1 PF12767.7 EKX32941.1 - 7.7e-28 97.8 0.1 7.3e-27 94.6 0.1 1.9 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.14 EKX32941.1 - 0.00015 21.7 1.4 0.00016 21.6 0.1 1.6 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family DUF3226 PF11536.8 EKX32941.1 - 0.058 13.1 0.0 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) PH PF00169.29 EKX32942.1 - 0.072 13.6 0.0 0.09 13.3 0.0 1.1 1 0 0 1 1 1 0 PH domain Retrotran_gag_3 PF14244.6 EKX32942.1 - 0.083 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Rota_Capsid_VP6 PF00980.17 EKX32943.1 - 0.13 11.1 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Rotavirus major capsid protein VP6 DUF778 PF05608.12 EKX32944.1 - 3.9e-25 89.3 1.4 7.5e-17 62.3 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF778) RRM_1 PF00076.22 EKX32945.1 - 9.3e-14 51.0 0.0 1e-13 50.9 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sep15_SelM PF08806.11 EKX32946.1 - 5.5e-06 26.4 0.0 8.2e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Sep15/SelM redox domain Neural_ProG_Cyt PF06567.11 EKX32946.1 - 0.18 12.0 0.0 0.22 11.8 0.0 1.1 1 0 0 1 1 1 0 Neural chondroitin sulphate proteoglycan cytoplasmic domain DUF563 PF04577.14 EKX32947.1 - 0.00053 20.2 0.0 0.086 13.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF563) KHA PF11834.8 EKX32948.1 - 6.3e-05 23.0 0.0 9.5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel zf-4CXXC_R1 PF10497.9 EKX32950.1 - 9.5e-07 29.0 22.5 1.2e-06 28.6 21.7 1.5 1 1 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 CAP_C PF08603.11 EKX32951.1 - 7.1e-06 25.7 1.1 1.4e-05 24.8 1.1 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 EKX32951.1 - 0.016 15.0 0.7 0.03 14.1 0.7 1.5 1 0 0 1 1 1 0 Tubulin binding cofactor C MGC-24 PF05283.11 EKX32951.1 - 0.06 13.8 1.6 0.14 12.6 1.6 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF5638 PF18688.1 EKX32953.1 - 0.06 13.7 0.5 0.11 12.8 0.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5638) Cytidylate_kin PF02224.18 EKX32956.1 - 2.1e-35 122.4 0.5 2.6e-35 122.1 0.5 1.0 1 0 0 1 1 1 1 Cytidylate kinase DUF1869 PF08956.10 EKX32956.1 - 0.17 11.8 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1869) PDZ PF00595.24 EKX32958.1 - 2.9e-06 27.5 0.3 6.1e-06 26.5 0.3 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX32958.1 - 0.00018 21.3 0.0 0.00037 20.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX32958.1 - 0.0051 17.1 0.5 0.021 15.1 0.0 2.4 3 0 0 3 3 3 1 PDZ domain Spore_III_AB PF09548.10 EKX32958.1 - 0.011 15.9 2.3 0.011 15.9 2.3 2.1 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) TMCO5 PF14992.6 EKX32958.1 - 0.71 9.4 19.5 0.086 12.4 15.2 1.7 2 0 0 2 2 2 0 TMCO5 family Allexi_40kDa PF05549.11 EKX32958.1 - 1 8.8 12.1 0.088 12.3 6.0 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein OmpH PF03938.14 EKX32958.1 - 3.2 8.1 17.8 5 7.5 15.2 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) NPV_P10 PF05531.12 EKX32958.1 - 9.3 6.8 11.2 6.5 7.3 2.2 3.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein PAP_fibrillin PF04755.12 EKX32959.1 - 2e-13 50.8 0.0 6e-13 49.2 0.0 1.8 2 1 0 2 2 2 1 PAP_fibrillin NmrA PF05368.13 EKX32960.1 - 1.1e-15 57.9 0.0 1.4e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EKX32960.1 - 2.8e-10 40.4 0.0 3.5e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding SlyX PF04102.12 EKX32961.1 - 0.048 14.3 25.3 1.7 9.3 0.2 5.4 2 2 4 6 6 6 0 SlyX DUF4686 PF15742.5 EKX32961.1 - 0.26 10.4 33.2 0.53 9.4 4.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4686) MAD PF05557.13 EKX32961.1 - 3.1 6.0 35.0 0.58 8.4 20.8 2.1 2 0 0 2 2 2 0 Mitotic checkpoint protein MHC2-interact PF09307.10 EKX32961.1 - 4.2 7.4 6.8 0.44 10.6 0.6 2.7 3 1 1 4 4 4 0 CLIP, MHC2 interacting Syntaxin-6_N PF09177.11 EKX32961.1 - 5.6 7.6 21.8 0.37 11.4 3.4 3.9 2 2 1 3 3 3 0 Syntaxin 6, N-terminal TSC22 PF01166.18 EKX32961.1 - 6.3 7.2 22.9 5.8 7.3 0.3 4.9 4 1 0 4 4 4 0 TSC-22/dip/bun family DivIC PF04977.15 EKX32961.1 - 6.3 6.7 32.3 3 7.7 3.5 5.2 3 1 2 5 5 5 0 Septum formation initiator Lipoprotein_20 PF13942.6 EKX32961.1 - 8.7 6.2 22.9 3.4 7.5 7.0 3.4 2 1 2 4 4 4 0 YfhG lipoprotein LMBR1 PF04791.16 EKX32961.1 - 9.2 5.0 7.6 12 4.6 7.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein TPR_17 PF13431.6 EKX32963.1 - 9e-16 57.0 15.3 0.003 17.8 0.0 9.0 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 EKX32963.1 - 2.8e-11 42.7 7.7 6.2e-05 22.9 0.1 8.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX32963.1 - 2.5e-09 36.6 20.1 0.0005 20.0 0.2 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX32963.1 - 9.3e-09 35.8 15.6 9.6e-05 23.0 0.3 6.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX32963.1 - 7.8e-08 32.7 17.6 0.0071 16.8 0.3 7.2 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX32963.1 - 2.5e-06 27.0 16.2 0.038 13.8 0.3 7.9 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX32963.1 - 1.9e-05 25.1 19.2 0.0087 16.8 0.4 7.6 5 3 3 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX32963.1 - 6.9e-05 23.1 5.4 0.0014 18.9 2.4 5.9 4 3 2 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX32963.1 - 0.00087 18.9 12.6 0.38 10.5 0.0 5.8 6 1 1 7 7 7 2 TPR repeat TPR_7 PF13176.6 EKX32963.1 - 0.0047 16.9 7.4 2 8.6 0.2 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat PknG_TPR PF16918.5 EKX32963.1 - 0.1 11.3 0.7 0.33 9.6 0.1 2.1 2 0 0 2 2 2 0 Protein kinase G tetratricopeptide repeat TPR_9 PF13371.6 EKX32963.1 - 0.13 12.4 9.0 2.7 8.2 0.0 4.7 5 1 0 5 5 4 0 Tetratricopeptide repeat Tcf25 PF04910.14 EKX32963.1 - 0.13 11.3 1.1 0.66 9.0 0.1 2.4 3 0 0 3 3 3 0 Transcriptional repressor TCF25 TPPII_N PF12583.8 EKX32963.1 - 0.17 12.5 3.6 14 6.3 0.1 4.7 4 1 1 5 5 5 0 Tripeptidyl peptidase II N terminal FAM176 PF14851.6 EKX32963.1 - 0.21 11.3 4.0 0.73 9.5 4.0 1.9 1 0 0 1 1 1 0 FAM176 family ANAPC3 PF12895.7 EKX32963.1 - 0.29 11.4 15.7 0.17 12.1 0.9 3.9 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 SAE2 PF08573.10 EKX32964.1 - 2.8e-07 31.6 0.8 2.8e-07 31.6 0.8 5.2 2 2 2 4 4 3 2 DNA repair protein endonuclease SAE2/CtIP C-terminus Calcipressin PF04847.12 EKX32964.1 - 0.001 18.8 0.3 0.006 16.3 0.0 2.4 2 0 0 2 2 2 1 Calcipressin HAP1_N PF04849.13 EKX32964.1 - 0.0012 18.1 10.1 0.0022 17.3 10.1 1.4 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Csm1_N PF18504.1 EKX32964.1 - 0.0065 16.8 0.7 0.0065 16.8 0.7 4.0 2 1 3 5 5 5 1 Csm1 N-terminal domain DUF4250 PF14056.6 EKX32964.1 - 0.0092 15.9 0.4 0.54 10.2 0.5 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4250) KASH_CCD PF14662.6 EKX32964.1 - 0.012 15.5 12.0 0.012 15.5 12.0 2.3 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH DUF1319 PF07028.11 EKX32964.1 - 0.043 14.0 2.1 0.056 13.7 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) CLZ PF16526.5 EKX32964.1 - 0.075 13.4 0.9 0.075 13.4 0.9 3.1 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Syntaxin PF00804.25 EKX32964.1 - 0.39 10.4 14.9 0.26 10.9 10.5 2.2 1 1 0 2 2 2 0 Syntaxin Prefoldin_2 PF01920.20 EKX32964.1 - 0.7 9.9 15.8 0.45 10.5 0.8 3.3 2 1 0 3 3 3 0 Prefoldin subunit Atg14 PF10186.9 EKX32964.1 - 0.85 8.6 10.9 1.7 7.7 10.9 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF848 PF05852.11 EKX32964.1 - 3.2 7.8 11.6 1.9 8.6 3.3 2.7 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Rootletin PF15035.6 EKX32964.1 - 3.7 7.5 20.2 0.022 14.8 10.6 2.1 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion RecG_N PF17190.4 EKX32964.1 - 3.9 8.3 8.7 12 6.8 3.7 2.5 1 1 1 2 2 2 0 RecG N-terminal helical domain DUF5082 PF16888.5 EKX32964.1 - 4.6 7.5 18.2 7.9 6.8 14.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF1664 PF07889.12 EKX32964.1 - 4.9 7.2 14.0 0.36 10.9 2.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Med9 PF07544.13 EKX32964.1 - 9.9 6.3 12.3 3.6 7.8 1.4 3.4 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 EamA PF00892.20 EKX32965.1 - 0.00047 20.4 7.8 0.17 12.1 1.6 2.4 2 1 1 3 3 3 2 EamA-like transporter family UAA PF08449.11 EKX32965.1 - 0.0073 15.6 4.8 0.0099 15.1 4.8 1.3 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 EKX32965.1 - 0.0076 15.6 2.7 0.0095 15.3 2.7 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Laminin_G_3 PF13385.6 EKX32966.1 - 1.8e-09 37.9 0.3 4.7e-09 36.6 0.2 1.7 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily V-ATPase_H_N PF03224.14 EKX32966.1 - 0.0024 17.2 0.1 0.0024 17.2 0.1 6.2 6 1 1 7 7 7 1 V-ATPase subunit H Flg_new PF09479.10 EKX32966.1 - 0.2 11.9 0.1 0.64 10.2 0.1 1.8 2 0 0 2 2 2 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) V-ATPase_H_C PF11698.8 EKX32966.1 - 0.4 10.8 4.5 0.64 10.2 0.2 3.8 3 0 0 3 3 3 0 V-ATPase subunit H Syntaxin-6_N PF09177.11 EKX32966.1 - 4.8 7.8 14.9 1.6 9.3 0.2 4.0 2 1 1 3 3 3 0 Syntaxin 6, N-terminal SecD-TM1 PF13721.6 EKX32966.1 - 5 7.6 5.2 36 4.9 0.0 3.1 3 0 0 3 3 3 0 SecD export protein N-terminal TM region HemX PF04375.14 EKX32966.1 - 7.2 5.8 17.1 5.8 6.1 14.2 2.3 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Cyclin_N PF00134.23 EKX32967.1 - 0.058 13.1 0.0 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 Cyclin, N-terminal domain PhyH PF05721.13 EKX32968.1 - 9.6e-25 88.1 0.6 3.9e-24 86.1 0.6 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DndB PF14072.6 EKX32969.1 - 0.0093 15.2 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 DNA-sulfur modification-associated DUF262 PF03235.14 EKX32969.1 - 0.041 14.1 0.4 0.049 13.8 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF262 TPR_8 PF13181.6 EKX32970.1 - 0.00049 20.1 0.0 0.71 10.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX32970.1 - 0.00061 19.7 0.0 2.4 8.5 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat BUD22 PF09073.10 EKX32970.1 - 0.001 18.5 17.0 0.001 18.5 17.0 1.6 2 0 0 2 2 2 1 BUD22 NodZ PF05830.11 EKX32970.1 - 0.094 11.5 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) G6B PF15096.6 EKX32970.1 - 0.64 9.8 4.1 4.4 7.0 0.0 2.8 2 0 0 2 2 2 0 G6B family DUF4746 PF15928.5 EKX32970.1 - 0.64 9.4 28.5 0.16 11.4 23.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) RNA_pol_3_Rpc31 PF11705.8 EKX32970.1 - 3.1 8.0 25.7 0.25 11.5 19.4 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Velvet PF11754.8 EKX32970.1 - 3.9 7.3 13.3 8 6.3 13.3 1.5 1 0 0 1 1 1 0 Velvet factor SpmSyn_N PF17950.1 EKX32971.1 - 0.049 13.8 0.1 0.049 13.8 0.1 2.9 3 0 0 3 3 3 0 S-adenosylmethionine decarboxylase N -terminal CHASE6_C PF17150.4 EKX32971.1 - 0.051 14.2 0.2 0.051 14.2 0.2 3.0 3 0 0 3 3 3 0 C-terminal domain of two-partite extracellular sensor domain OKR_DC_1_N PF03709.15 EKX32971.1 - 0.14 12.4 0.9 0.59 10.4 0.0 2.4 3 1 0 3 3 3 0 Orn/Lys/Arg decarboxylase, N-terminal domain TPR_2 PF07719.17 EKX32971.1 - 0.17 12.0 2.0 1.3 9.3 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Tic22 PF04278.12 EKX32971.1 - 0.69 9.2 4.0 1.1 8.6 0.4 2.6 3 0 0 3 3 3 0 Tic22-like family DUF1041 PF06292.17 EKX32971.1 - 1.4 9.3 5.2 0.39 11.2 0.2 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1041) DUF1993 PF09351.10 EKX32971.1 - 3.3 7.8 0.0 3.3 7.8 0.0 3.7 3 2 1 5 5 5 0 Domain of unknown function (DUF1993) FUSC-like PF12805.7 EKX32971.1 - 4.9 6.1 6.4 4.5 6.3 4.0 2.1 1 1 1 2 2 2 0 FUSC-like inner membrane protein yccS Ank_2 PF12796.7 EKX32974.1 - 2.6e-37 127.2 0.1 1.2e-09 38.6 0.0 4.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX32974.1 - 9e-27 93.1 0.2 6e-08 33.1 0.1 6.2 6 1 1 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX32974.1 - 1.2e-15 56.0 0.0 0.11 13.2 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EKX32974.1 - 2.5e-15 56.3 0.8 0.054 13.8 0.0 6.1 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 EKX32974.1 - 8.2e-13 48.2 0.0 0.34 11.4 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat AsnC_trans_reg2 PF17805.1 EKX32974.1 - 0.11 12.7 0.0 19 5.5 0.0 2.8 2 1 1 3 3 3 0 AsnC-like ligand binding domain LigB PF02900.18 EKX32975.1 - 3.7e-40 137.7 0.0 4.5e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Peptidase_C65 PF10275.9 EKX32976.1 - 1.9e-38 132.3 0.0 3.4e-38 131.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase C65 Otubain C2 PF00168.30 EKX32976.1 - 1.1e-07 32.0 0.0 2.8e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 C2 domain Peptidase_C101 PF16218.5 EKX32976.1 - 0.17 11.1 0.7 1 8.6 0.0 2.4 3 0 0 3 3 3 0 Peptidase family C101 TPR_12 PF13424.6 EKX32977.1 - 8.1e-17 61.3 25.3 8e-07 29.3 2.4 4.4 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 EKX32977.1 - 7.8e-13 47.7 19.9 0.048 13.5 0.1 5.5 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 EKX32977.1 - 9.9e-12 44.1 17.6 0.019 15.2 0.9 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 EKX32977.1 - 1.9e-09 36.9 17.2 0.056 13.6 1.4 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX32977.1 - 3.6e-09 36.0 14.1 0.075 13.1 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX32977.1 - 1.4e-05 24.6 7.2 6.6e-05 22.4 3.5 2.1 1 1 1 2 2 2 1 MalT-like TPR region TPR_10 PF13374.6 EKX32977.1 - 0.018 14.9 16.2 1.7 8.6 0.8 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX32977.1 - 0.019 15.6 10.2 6 7.7 0.7 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX32977.1 - 0.093 13.3 6.4 5.3 7.6 0.5 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat MazG PF03819.17 EKX32977.1 - 0.12 12.5 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain PPR PF01535.20 EKX32977.1 - 0.15 12.4 0.2 8.2 6.9 0.0 2.9 2 0 0 2 2 2 0 PPR repeat TPR_11 PF13414.6 EKX32977.1 - 0.3 10.8 15.6 2.3 8.0 0.0 4.9 5 0 0 5 5 5 0 TPR repeat TPR_17 PF13431.6 EKX32977.1 - 1.5 9.4 9.4 2.5 8.7 0.2 4.1 4 2 1 5 5 4 0 Tetratricopeptide repeat Ham1p_like PF01725.16 EKX32978.1 - 4.5e-06 26.7 0.0 7.9e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Ham1 family TT_ORF1 PF02956.14 EKX32978.1 - 4.5 5.8 5.6 6.8 5.2 5.6 1.2 1 0 0 1 1 1 0 TT viral orf 1 AAA PF00004.29 EKX32979.1 - 5e-19 69.0 0.0 9.1e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX32979.1 - 7e-05 23.3 0.0 0.00028 21.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EKX32979.1 - 0.00037 20.8 0.1 0.0082 16.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EKX32979.1 - 0.00077 19.5 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EKX32979.1 - 0.0015 18.0 0.1 0.0026 17.2 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EKX32979.1 - 0.0079 16.8 0.0 0.013 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EKX32979.1 - 0.035 13.8 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 EKX32979.1 - 0.05 14.1 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 EKX32979.1 - 0.051 14.0 0.0 0.094 13.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 EKX32979.1 - 0.054 13.4 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 EKX32979.1 - 0.093 12.6 0.1 0.52 10.2 0.1 2.1 1 1 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 EKX32979.1 - 0.097 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain TMEM132D_N PF15705.5 EKX32979.1 - 0.12 12.2 0.6 7 6.5 0.0 2.3 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term AAA_7 PF12775.7 EKX32979.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EKX32979.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain PCO_ADO PF07847.12 EKX32979.1 - 0.19 11.1 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 PCO_ADO ATPase_2 PF01637.18 EKX32979.1 - 0.25 11.2 0.1 1 9.2 0.0 1.8 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Virulence_fact PF13769.6 EKX32982.1 - 0.16 12.2 0.0 0.48 10.7 0.0 1.7 2 0 0 2 2 2 0 Virulence factor SecY PF00344.20 EKX32983.1 - 1.8e-70 237.6 11.9 2.3e-70 237.3 11.9 1.1 1 0 0 1 1 1 1 SecY translocase AZUL PF16558.5 EKX32984.1 - 1.5e-15 57.1 3.0 3.2e-15 56.1 3.0 1.6 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A HECT PF00632.25 EKX32984.1 - 1.8e-15 57.2 0.0 4.2e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arg_decarb_HB PF17810.1 EKX32984.1 - 0.0081 16.4 0.0 0.51 10.6 0.0 2.5 2 0 0 2 2 2 1 Arginine decarboxylase helical bundle domain Pro_isomerase PF00160.21 EKX32985.1 - 3.8e-14 53.3 0.0 7.5e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cyclin_N PF00134.23 EKX32986.1 - 5.6e-10 39.0 1.1 8.8e-10 38.4 1.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain ADH_zinc_N PF00107.26 EKX32987.1 - 1.6e-11 44.3 0.0 2.9e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EKX32987.1 - 2.9e-10 41.3 0.0 1.1e-09 39.5 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EKX32987.1 - 5.8e-05 22.9 0.0 0.00014 21.8 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AsnC_trans_reg PF01037.21 EKX32988.1 - 0.023 14.7 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain FRG1 PF06229.12 EKX32989.1 - 0.61 9.8 12.7 1.9 8.2 0.7 2.6 2 1 1 3 3 3 0 FRG1-like domain EFP PF01132.20 EKX32991.1 - 5.1e-12 45.6 0.1 9.2e-12 44.8 0.1 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain Elong-fact-P_C PF09285.11 EKX32991.1 - 1.3e-08 34.4 0.3 3.3e-08 33.2 0.2 1.7 2 0 0 2 2 2 1 Elongation factor P, C-terminal EFP_N PF08207.12 EKX32991.1 - 2.5e-08 33.8 0.5 4.3e-08 33.1 0.5 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain YceD PF02620.17 EKX32991.1 - 0.04 14.0 0.1 0.06 13.5 0.1 1.3 1 0 0 1 1 1 0 Large ribosomal RNA subunit accumulation protein YceD PH_11 PF15413.6 EKX32991.1 - 0.1 13.1 0.3 0.22 11.9 0.3 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain TBP PF00352.21 EKX32993.1 - 0.067 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Transcription factor TFIID (or TATA-binding protein, TBP) Nop14 PF04147.12 EKX32994.1 - 0.018 13.3 40.7 0.02 13.2 40.7 1.0 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.16 EKX32994.1 - 0.051 12.8 17.0 0.071 12.3 17.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Mpp10 PF04006.12 EKX32994.1 - 0.056 11.9 33.7 0.063 11.7 33.7 1.0 1 0 0 1 1 1 0 Mpp10 protein DNA_pol_phi PF04931.13 EKX32994.1 - 0.061 11.4 51.4 0.066 11.3 51.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi SID-1_RNA_chan PF13965.6 EKX32994.1 - 0.066 11.6 2.0 0.076 11.4 2.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RNA_pol_Rpc4 PF05132.14 EKX32994.1 - 0.096 13.1 7.7 0.12 12.8 7.7 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Zip PF02535.22 EKX32994.1 - 0.13 11.5 4.8 0.13 11.5 4.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter IFT57 PF10498.9 EKX32994.1 - 0.23 10.4 16.6 0.3 10.0 16.6 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 SpoIIP PF07454.11 EKX32994.1 - 0.31 10.5 9.6 0.33 10.4 9.6 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF913 PF06025.12 EKX32994.1 - 0.35 9.8 9.3 0.38 9.7 9.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Vfa1 PF08432.10 EKX32994.1 - 0.38 11.1 17.1 0.56 10.5 17.1 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF5523 PF17661.1 EKX32994.1 - 0.39 10.4 19.4 0.51 10.0 19.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5523) SpoIIIAH PF12685.7 EKX32994.1 - 0.51 10.1 15.7 0.55 10.0 15.7 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein V_ATPase_I PF01496.19 EKX32994.1 - 0.51 8.2 8.4 0.55 8.1 8.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RPN2_C PF18004.1 EKX32994.1 - 0.56 10.1 16.9 0.8 9.6 16.9 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4746 PF15928.5 EKX32994.1 - 0.66 9.3 16.8 0.81 9.0 16.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CobT PF06213.12 EKX32994.1 - 0.78 9.1 34.8 0.89 8.9 34.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Presenilin PF01080.17 EKX32994.1 - 0.89 8.2 9.9 0.91 8.2 9.9 1.0 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 EKX32994.1 - 0.9 7.8 33.7 1 7.6 33.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 EKX32994.1 - 0.99 8.3 6.6 1 8.3 6.6 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Connexin PF00029.19 EKX32994.1 - 1.3 8.7 4.7 1.5 8.5 4.7 1.3 1 0 0 1 1 1 0 Connexin Serinc PF03348.15 EKX32994.1 - 1.4 7.8 3.4 1.7 7.5 3.4 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Trypan_PARP PF05887.11 EKX32994.1 - 2 8.4 27.5 2.7 8.0 27.5 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RRN3 PF05327.11 EKX32994.1 - 2.3 6.7 30.7 2.4 6.6 30.7 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RR_TM4-6 PF06459.12 EKX32994.1 - 2.6 7.8 14.2 3.2 7.5 14.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 EKX32994.1 - 6 5.5 17.3 6.4 5.4 17.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MAP17 PF15807.5 EKX32994.1 - 8.2 6.7 9.0 10 6.4 9.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Sec62 PF03839.16 EKX32994.1 - 8.5 5.8 6.2 11 5.4 6.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 NPR3 PF03666.13 EKX32994.1 - 9.2 4.9 16.3 10 4.8 16.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FKBP_C PF00254.28 EKX32996.1 - 6e-20 71.4 0.0 1.1e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PDZ_6 PF17820.1 EKX32996.1 - 0.0004 20.2 0.3 0.0051 16.6 0.0 2.5 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX32996.1 - 0.0052 17.1 0.5 0.013 15.9 0.1 1.9 2 0 0 2 2 2 1 PDZ domain Arm PF00514.23 EKX32997.1 - 0.0033 17.4 0.0 0.33 11.1 0.0 3.0 2 1 1 3 3 3 1 Armadillo/beta-catenin-like repeat ANTAR PF03861.14 EKX32997.1 - 0.0094 15.8 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 ANTAR domain HECT PF00632.25 EKX32998.1 - 1.7e-58 198.6 0.0 5.5e-58 196.9 0.0 1.8 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Rad9 PF04139.13 EKX32999.1 - 1.4e-07 31.2 0.2 2.4e-07 30.5 0.2 1.3 1 0 0 1 1 1 1 Rad9 LRR_8 PF13855.6 EKX33000.1 - 1e-73 243.0 63.4 7.9e-16 57.6 1.7 6.9 1 1 6 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 EKX33000.1 - 3.9e-27 93.8 36.4 3.5e-05 24.1 0.3 8.1 4 1 6 10 10 10 10 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX33000.1 - 9.1e-27 93.5 0.7 4.6e-10 39.5 0.0 3.3 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EKX33000.1 - 6.6e-13 47.3 43.9 0.088 13.4 0.0 11.7 14 0 0 14 14 14 7 Leucine Rich Repeat LRR_9 PF14580.6 EKX33000.1 - 1.8e-12 47.1 5.6 0.0067 15.9 0.0 4.2 1 1 3 4 4 4 4 Leucine-rich repeat DUF3106 PF11304.8 EKX33002.1 - 0.041 14.4 1.5 0.041 14.4 1.5 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3106) TetR_C_24 PF17932.1 EKX33002.1 - 0.2 11.9 2.1 0.33 11.2 1.0 1.8 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain COMP PF11598.8 EKX33002.1 - 7.3 7.2 9.3 1.2 9.7 0.5 3.4 4 0 0 4 4 4 0 Cartilage oligomeric matrix protein TBP PF00352.21 EKX33003.1 - 4.3e-06 26.6 0.0 0.0044 16.9 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) Lyase_1 PF00206.20 EKX33004.1 - 3.2e-94 315.8 0.0 3.6e-94 315.7 0.0 1.0 1 0 0 1 1 1 1 Lyase ANTH PF07651.16 EKX33005.1 - 1.1e-23 83.6 5.1 2.2e-16 59.7 4.0 2.5 2 1 0 2 2 2 2 ANTH domain IGPS PF00218.21 EKX33006.1 - 0.0003 20.1 1.0 0.00073 18.8 1.0 1.6 1 1 0 1 1 1 1 Indole-3-glycerol phosphate synthase PucR PF07905.11 EKX33006.1 - 0.032 14.5 0.3 0.52 10.6 0.0 2.1 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family NmrA PF05368.13 EKX33006.1 - 0.032 13.8 1.3 0.048 13.2 0.7 1.5 1 1 1 2 2 2 0 NmrA-like family SRCR PF00530.18 EKX33009.1 - 2e-127 416.5 84.2 4.8e-23 81.6 8.9 6.2 6 0 0 6 6 6 6 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 EKX33009.1 - 6.6e-17 61.9 31.7 0.0084 16.6 1.1 5.8 5 0 0 5 5 5 5 Scavenger receptor cysteine-rich domain zf-C3HC4_2 PF13923.6 EKX33009.1 - 8.6e-07 28.7 7.7 5.7 6.9 0.0 5.9 5 0 0 5 5 5 4 Zinc finger, C3HC4 type (RING finger) S6PP_C PF08472.10 EKX33009.1 - 0.017 15.0 0.0 68 3.3 0.0 5.0 6 0 0 6 6 6 0 Sucrose-6-phosphate phosphohydrolase C-terminal DUF1726 PF08351.11 EKX33009.1 - 0.23 11.4 2.9 3.4e+02 1.3 0.0 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF1726) LIAS_N PF16881.5 EKX33010.1 - 0.0022 18.4 0.3 0.014 15.8 0.2 1.9 1 1 1 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family PHD PF00628.29 EKX33011.1 - 1.4e-11 44.0 2.5 1.7e-11 43.9 2.5 1.1 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 EKX33011.1 - 0.001 18.9 1.2 0.001 18.9 1.2 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-rbx1 PF12678.7 EKX33011.1 - 0.0019 18.4 1.3 0.0022 18.3 1.3 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EKX33011.1 - 0.015 15.7 3.1 0.019 15.3 3.1 1.2 1 0 0 1 1 1 0 Ring finger domain zf-RanBP PF00641.18 EKX33011.1 - 0.035 13.4 2.8 0.86 9.0 1.0 2.6 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others FANCL_C PF11793.8 EKX33011.1 - 0.037 14.2 0.8 0.046 13.9 0.8 1.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-FPG_IleRS PF06827.14 EKX33011.1 - 0.071 13.0 4.5 3.2 7.7 0.1 2.8 3 1 0 3 3 3 0 Zinc finger found in FPG and IleRS Prim_Zn_Ribbon PF08273.12 EKX33011.1 - 0.84 10.0 8.2 0.65 10.3 2.0 2.5 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase AAA PF00004.29 EKX33012.1 - 1.5e-39 135.5 0.0 1.9e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EKX33012.1 - 2e-11 43.5 0.1 5.2e-11 42.2 0.0 1.8 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 EKX33012.1 - 1.1e-07 32.3 0.1 0.0059 17.0 0.0 2.5 1 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EKX33012.1 - 7e-07 29.6 0.6 0.01 16.1 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.14 EKX33012.1 - 8.9e-07 29.0 0.7 2.6e-05 24.2 0.7 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EKX33012.1 - 1.7e-06 27.8 0.0 4e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EKX33012.1 - 2.1e-06 27.2 0.0 3.9e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 EKX33012.1 - 8.7e-05 23.1 0.0 0.00013 22.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EKX33012.1 - 0.00021 21.3 0.0 0.0003 20.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EKX33012.1 - 0.00045 20.0 0.0 0.00088 19.0 0.0 1.5 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 EKX33012.1 - 0.00098 19.3 0.0 0.0013 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EKX33012.1 - 0.0011 18.9 0.6 0.66 9.9 0.2 2.2 1 1 1 2 2 2 2 NACHT domain AAA_2 PF07724.14 EKX33012.1 - 0.0014 18.7 0.0 0.0025 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_3 PF07726.11 EKX33012.1 - 0.0015 18.4 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EKX33012.1 - 0.0036 16.8 0.0 0.0063 16.0 0.0 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region TsaE PF02367.17 EKX33012.1 - 0.0036 17.3 0.0 0.0054 16.7 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 EKX33012.1 - 0.0048 16.8 0.1 0.02 14.8 0.1 1.8 1 1 0 1 1 1 1 Bacterial dnaA protein DUF815 PF05673.13 EKX33012.1 - 0.011 14.9 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EKX33012.1 - 0.014 15.8 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.18 EKX33012.1 - 0.014 15.1 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 EKX33012.1 - 0.015 15.5 0.0 0.051 13.8 0.0 1.8 1 1 1 2 2 2 0 AAA domain TniB PF05621.11 EKX33012.1 - 0.02 14.3 0.1 2.3 7.6 0.0 2.2 1 1 1 2 2 2 0 Bacterial TniB protein AAA_17 PF13207.6 EKX33012.1 - 0.022 15.2 0.0 0.042 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_6 PF12774.7 EKX33012.1 - 0.022 13.7 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Zeta_toxin PF06414.12 EKX33012.1 - 0.023 14.0 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.21 EKX33012.1 - 0.024 14.0 0.1 0.048 13.0 0.1 1.5 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cytidylate_kin PF02224.18 EKX33012.1 - 0.025 14.3 0.1 0.59 9.8 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase Sigma54_activat PF00158.26 EKX33012.1 - 0.026 14.2 0.0 0.1 12.3 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 EKX33012.1 - 0.033 14.1 0.0 0.35 10.8 0.0 2.0 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EKX33012.1 - 0.041 13.6 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EKX33012.1 - 0.047 13.4 0.0 0.098 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 EKX33012.1 - 0.051 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.9 EKX33012.1 - 0.078 12.7 0.0 1.5 8.6 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Parvo_NS1 PF01057.17 EKX33012.1 - 0.087 11.9 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 IPT PF01745.16 EKX33012.1 - 0.12 11.8 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase AAA_19 PF13245.6 EKX33012.1 - 0.13 12.6 0.1 0.39 11.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain WD40 PF00400.32 EKX33013.1 - 4.7e-27 93.7 22.1 0.00018 22.2 1.9 11.1 11 0 0 11 11 11 6 WD domain, G-beta repeat SNARE_assoc PF09335.11 EKX33013.1 - 2.7e-13 50.5 5.5 2.7e-13 50.5 5.5 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein Nup160 PF11715.8 EKX33013.1 - 5.9e-11 41.7 4.3 0.4 9.3 0.1 7.1 3 1 2 7 7 7 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EKX33013.1 - 2.3e-05 23.3 3.5 3.5 6.3 0.0 5.4 3 1 3 6 6 6 3 Nup133 N terminal like RAB3GAP2_N PF14655.6 EKX33013.1 - 0.009 15.3 0.0 0.081 12.2 0.0 2.3 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus ANAPC4_WD40 PF12894.7 EKX33013.1 - 0.0095 16.2 1.1 24 5.3 0.1 4.9 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain UDPG_MGDP_dh PF00984.19 EKX33014.1 - 1.9e-25 88.9 0.0 3.5e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_N PF03721.14 EKX33014.1 - 4e-24 85.2 0.0 5.6e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EKX33014.1 - 2.1e-06 27.8 0.0 3.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 EKX33014.1 - 3.8e-06 27.2 0.0 8.6e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 EKX33014.1 - 0.00027 20.6 0.1 0.00059 19.5 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EKX33014.1 - 0.0016 18.3 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 EKX33014.1 - 0.002 17.7 0.1 0.026 14.1 0.1 2.1 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 EKX33014.1 - 0.0041 17.7 0.1 0.021 15.4 0.0 2.3 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EKX33014.1 - 0.032 13.6 0.1 0.11 11.8 0.1 1.9 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SRP54 PF00448.22 EKX33015.1 - 0.00011 21.9 0.0 0.0029 17.3 0.0 2.2 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain Ank_2 PF12796.7 EKX33016.1 - 3.2e-10 40.4 1.0 3.1e-06 27.7 0.7 3.1 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX33016.1 - 1.2e-08 35.3 0.2 1.7e-05 25.3 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) UvrD-helicase PF00580.21 EKX33016.1 - 4.9e-07 29.6 0.7 4.9e-07 29.6 0.7 5.7 5 1 0 5 5 5 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 EKX33016.1 - 8.3e-07 28.7 0.0 0.057 13.3 0.0 3.0 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EKX33016.1 - 6.6e-06 26.5 2.0 8.9e-05 22.9 0.0 3.7 3 1 0 3 3 3 1 AAA domain Ank_5 PF13857.6 EKX33016.1 - 1.4e-05 25.3 0.2 0.013 15.8 0.1 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX33016.1 - 2.1e-05 24.5 0.8 0.043 14.4 0.0 4.9 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 EKX33016.1 - 0.017 15.6 11.3 0.25 11.9 0.2 5.1 5 0 0 5 5 5 0 Ankyrin repeat FTCD_C PF04961.12 EKX33017.1 - 0.0029 17.4 0.2 0.0052 16.6 0.2 1.4 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase PET PF06297.14 EKX33017.1 - 0.12 12.7 0.6 3.6 8.0 0.0 2.6 2 0 0 2 2 2 0 PET Domain KIAA1430 PF13879.6 EKX33019.1 - 0.026 15.3 0.9 0.047 14.4 0.5 1.7 1 1 0 1 1 1 0 KIAA1430 homologue Band_7 PF01145.25 EKX33020.1 - 3.4e-32 111.9 0.1 4.9e-32 111.4 0.1 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 EKX33020.1 - 0.0043 16.8 0.2 0.01 15.5 0.1 1.7 2 0 0 2 2 2 1 SPFH domain-Band 7 family Ribosomal_S3Ae PF01015.18 EKX33020.1 - 0.022 14.4 1.8 0.025 14.2 0.9 1.5 1 1 0 1 1 1 0 Ribosomal S3Ae family Taq-exonuc PF09281.10 EKX33020.1 - 0.18 11.8 1.4 0.29 11.2 1.4 1.4 1 0 0 1 1 1 0 Taq polymerase, exonuclease Band_7 PF01145.25 EKX33021.1 - 9.8e-33 113.6 0.1 1.5e-32 113.0 0.1 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 EKX33021.1 - 0.0062 16.3 0.2 0.014 15.1 0.1 1.6 2 0 0 2 2 2 1 SPFH domain-Band 7 family Ribosomal_S3Ae PF01015.18 EKX33021.1 - 0.021 14.4 1.7 0.025 14.2 1.0 1.5 1 1 0 1 1 1 0 Ribosomal S3Ae family DUF4190 PF13828.6 EKX33022.1 - 0.0075 16.0 0.3 0.0083 15.9 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4190) TPR_19 PF14559.6 EKX33023.1 - 9.6e-16 58.1 9.6 0.11 13.0 0.0 7.6 7 1 0 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 EKX33023.1 - 3.1e-11 43.1 11.1 0.74 10.8 0.0 9.5 6 3 4 10 10 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX33023.1 - 2.5e-09 37.6 0.0 0.31 11.7 0.0 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX33023.1 - 4.2e-09 35.8 3.2 4.2 7.7 0.0 8.1 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 EKX33023.1 - 1.9e-07 31.0 3.1 1.2 9.7 0.1 6.4 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX33023.1 - 3.2e-06 26.7 1.0 1.5 8.8 0.1 5.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX33023.1 - 3.4e-05 23.4 1.9 0.011 15.4 0.0 4.1 5 0 0 5 5 5 1 TPR repeat TPR_6 PF13174.6 EKX33023.1 - 0.00012 22.5 2.9 2.2 9.1 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX33023.1 - 0.00012 22.0 3.6 64 4.1 0.0 6.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX33023.1 - 0.0026 18.0 10.6 1.2 9.5 0.3 6.5 6 2 1 7 7 7 1 Tetratricopeptide repeat Bap31_Bap29_C PF18035.1 EKX33023.1 - 0.049 13.6 0.7 4.7 7.3 0.1 2.5 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain ANAPC3 PF12895.7 EKX33023.1 - 0.44 10.8 13.0 3.8 7.8 0.1 5.3 5 1 2 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 Morc6_S5 PF17942.1 EKX33024.1 - 3.4e-11 43.4 0.0 7.7e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Morc6 ribosomal protein S5 domain 2-like Trypan_PARP PF05887.11 EKX33024.1 - 0.0049 16.8 12.2 0.0049 16.8 12.2 2.0 2 0 0 2 2 1 1 Procyclic acidic repetitive protein (PARP) AAA_23 PF13476.6 EKX33024.1 - 0.064 13.7 13.1 0.065 13.7 10.7 2.2 2 0 0 2 2 2 0 AAA domain SpoIIP PF07454.11 EKX33024.1 - 0.1 12.1 15.1 0.21 11.0 15.1 1.5 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DDHD PF02862.17 EKX33024.1 - 0.28 11.3 13.3 0.023 14.8 8.4 1.7 2 0 0 2 2 1 0 DDHD domain DUF913 PF06025.12 EKX33024.1 - 0.46 9.4 13.5 0.89 8.5 13.5 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Plasmodium_Vir PF05795.11 EKX33024.1 - 0.61 9.5 10.5 1.1 8.6 10.5 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CobT PF06213.12 EKX33024.1 - 0.61 9.4 33.0 1.6 8.1 33.0 1.7 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TRAP_alpha PF03896.16 EKX33024.1 - 0.74 9.0 11.3 1.3 8.1 11.3 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 EKX33024.1 - 0.77 8.0 23.1 0.017 13.5 13.5 2.1 2 0 0 2 2 2 0 CDC45-like protein Eapp_C PF10238.9 EKX33024.1 - 0.97 9.5 12.5 3 7.9 12.5 1.9 1 0 0 1 1 1 0 E2F-associated phosphoprotein SLC12 PF03522.15 EKX33024.1 - 1.2 8.0 13.8 2.4 7.1 13.8 1.4 1 0 0 1 1 1 0 Solute carrier family 12 DREPP PF05558.12 EKX33024.1 - 1.3 8.9 15.2 3.5 7.4 15.2 1.8 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide DUF1682 PF07946.14 EKX33024.1 - 1.3 8.2 16.2 2.8 7.1 16.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) RRN3 PF05327.11 EKX33024.1 - 1.4 7.4 12.1 2.2 6.7 12.1 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Dynamin_N PF00350.23 EKX33024.1 - 2 8.4 5.8 4.5 7.3 5.8 1.6 1 0 0 1 1 1 0 Dynamin family MDM10 PF12519.8 EKX33024.1 - 2.2 7.0 12.3 4.4 6.1 12.3 1.5 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 TERB2 PF15101.6 EKX33024.1 - 3.1 7.8 17.3 7.4 6.6 17.3 1.6 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Afi1 PF07792.12 EKX33024.1 - 3.9 8.0 17.3 14 6.2 17.3 2.0 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CENP-O PF09496.10 EKX33024.1 - 4.9 7.1 16.3 13 5.7 16.3 1.8 1 1 0 1 1 1 0 Cenp-O kinetochore centromere component DUF3402 PF11882.8 EKX33024.1 - 5.7 5.9 17.2 2.6 7.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) Zip PF02535.22 EKX33024.1 - 6.9 5.8 8.8 13 4.9 8.8 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2370 PF10176.9 EKX33024.1 - 8.4 6.0 5.9 18 4.9 5.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Raftlin PF15250.6 EKX33024.1 - 9.1 4.9 17.5 18 4.0 17.5 1.4 1 0 0 1 1 1 0 Raftlin Guanylate_kin PF00625.21 EKX33025.1 - 1.8e-23 83.2 0.0 4.7e-23 81.8 0.0 1.5 2 0 0 2 2 2 1 Guanylate kinase AAA_16 PF13191.6 EKX33025.1 - 0.0014 19.0 0.0 0.0016 18.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 EKX33025.1 - 0.0027 17.8 0.0 0.0038 17.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 EKX33025.1 - 0.044 14.2 0.0 0.082 13.3 0.0 1.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 EKX33025.1 - 0.052 13.5 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 NTPase RsgA_GTPase PF03193.16 EKX33025.1 - 0.076 12.9 0.0 0.095 12.6 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase RuvB_N PF05496.12 EKX33025.1 - 0.11 12.3 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain T2SSE PF00437.20 EKX33025.1 - 0.22 10.6 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein LRR_8 PF13855.6 EKX33026.1 - 4.6e-31 106.4 29.7 2.5e-10 40.0 0.7 3.6 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 EKX33026.1 - 1.3e-15 57.2 9.2 2.5e-05 24.5 0.9 4.2 2 2 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX33026.1 - 0.00028 20.4 1.9 0.0025 17.4 0.1 2.3 2 0 0 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 EKX33026.1 - 0.00056 20.1 11.1 3.2 8.6 0.1 5.9 6 0 0 6 6 6 1 Leucine Rich Repeat RNA_pol_3_Rpc31 PF11705.8 EKX33026.1 - 0.0015 18.8 4.0 0.0015 18.8 4.0 2.4 2 0 0 2 2 1 1 DNA-directed RNA polymerase III subunit Rpc31 LRR_6 PF13516.6 EKX33026.1 - 0.0022 17.9 12.5 4 7.7 0.1 5.5 6 0 0 6 6 5 1 Leucine Rich repeat CENP-B_dimeris PF09026.10 EKX33026.1 - 0.0026 18.1 4.9 0.0026 18.1 4.9 2.6 2 0 0 2 2 2 1 Centromere protein B dimerisation domain BUD22 PF09073.10 EKX33026.1 - 0.0048 16.3 15.4 0.0064 15.9 3.6 2.2 2 0 0 2 2 2 2 BUD22 BSP_II PF05432.11 EKX33026.1 - 0.013 15.2 7.9 0.013 15.2 7.9 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Gemini_C4 PF01492.17 EKX33026.1 - 0.014 15.3 0.2 0.099 12.6 0.0 2.2 2 0 0 2 2 2 0 Geminivirus C4 protein Rhabdo_NV PF02484.15 EKX33026.1 - 0.023 14.9 0.1 2.3 8.4 0.0 2.8 2 1 1 3 3 3 0 Rhabdovirus Non-virion protein Mlh1_C PF16413.5 EKX33026.1 - 0.088 12.2 1.2 7.3 5.9 0.0 2.3 2 0 0 2 2 2 0 DNA mismatch repair protein Mlh1 C-terminus RNase_H2_suC PF08615.11 EKX33026.1 - 0.096 12.9 1.5 7.6 6.7 0.1 2.3 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF4611 PF15387.6 EKX33026.1 - 0.12 12.6 29.7 0.56 10.5 12.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF2457 PF10446.9 EKX33026.1 - 0.35 10.0 32.9 0.02 14.1 10.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) FAM176 PF14851.6 EKX33026.1 - 0.59 9.8 20.1 1.4 8.6 6.9 2.4 2 0 0 2 2 2 0 FAM176 family SDA1 PF05285.12 EKX33026.1 - 2.2 7.6 26.1 0.057 12.8 7.3 2.1 2 0 0 2 2 2 0 SDA1 PBP1_TM PF14812.6 EKX33026.1 - 2.5 8.5 27.9 0.94 9.9 11.9 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.11 EKX33026.1 - 4.3 7.3 24.5 2.4 8.2 8.2 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal GEN1_C PF18380.1 EKX33026.1 - 6 7.8 17.3 12 6.8 7.3 2.5 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain CDC45 PF02724.14 EKX33026.1 - 8 4.6 25.7 0.14 10.5 9.2 2.1 2 0 0 2 2 2 0 CDC45-like protein zf-RING_4 PF14570.6 EKX33027.1 - 1.1e-18 66.8 13.0 1.3e-18 66.5 13.0 1.1 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 EKX33027.1 - 2.4e-06 27.3 14.5 4.5e-06 26.4 14.5 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX33027.1 - 5.8e-06 26.5 13.9 6.9e-06 26.3 13.9 1.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EKX33027.1 - 8.5e-05 22.3 15.1 0.00011 21.9 15.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 EKX33027.1 - 0.0023 18.0 8.0 0.0065 16.6 7.9 1.7 1 1 1 2 2 2 1 Zinc-binding RING-finger zf-RING_5 PF14634.6 EKX33027.1 - 0.0082 16.1 12.7 0.013 15.4 12.7 1.4 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EKX33027.1 - 0.018 14.9 14.5 0.032 14.1 6.0 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EKX33027.1 - 0.019 14.8 15.0 0.027 14.3 15.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TerY_C PF15616.6 EKX33027.1 - 0.05 13.7 7.5 0.06 13.5 7.5 1.2 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_UBOX PF13445.6 EKX33027.1 - 0.073 13.1 12.3 0.11 12.6 12.3 1.3 1 0 0 1 1 1 0 RING-type zinc-finger YdjO PF14169.6 EKX33027.1 - 0.13 12.0 0.3 0.13 12.0 0.3 2.6 2 1 1 3 3 3 0 Cold-inducible protein YdjO zf-C3HC4_5 PF17121.5 EKX33027.1 - 0.39 10.6 11.9 0.64 10.0 11.9 1.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.21 EKX33027.1 - 0.57 10.4 11.4 0.53 10.6 8.5 2.0 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Baculo_IE-1 PF05290.11 EKX33027.1 - 1.8 8.5 9.5 3.8 7.4 9.6 1.4 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RVT PF13966.6 EKX33027.1 - 2.6 8.8 8.7 0.26 12.0 2.1 2.0 1 1 0 2 2 2 0 zinc-binding in reverse transcriptase Proteasome PF00227.26 EKX33028.1 - 8.7e-40 136.2 0.0 3.4e-39 134.3 0.0 1.9 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EKX33028.1 - 9.3e-08 31.6 0.1 2.5e-07 30.3 0.1 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SpoVT_C PF15714.5 EKX33029.1 - 0.077 13.1 0.7 0.12 12.4 0.7 1.2 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor Arm PF00514.23 EKX33030.1 - 3.8e-14 52.1 1.7 0.00016 21.6 0.0 6.0 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EKX33030.1 - 0.019 15.5 0.4 26 5.5 0.0 3.8 3 1 1 4 4 4 0 HEAT-like repeat Adaptin_N PF01602.20 EKX33030.1 - 0.048 12.2 0.0 0.092 11.3 0.0 1.5 1 1 0 1 1 1 0 Adaptin N terminal region Cnd1 PF12717.7 EKX33030.1 - 0.063 13.3 0.0 0.2 11.7 0.0 1.9 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Thioredoxin_13 PF18401.1 EKX33030.1 - 0.15 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain Med25_VWA PF11265.8 EKX33031.1 - 8.9e-17 61.6 0.0 1.3e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A Spc42p PF11544.8 EKX33034.1 - 0.094 12.7 0.4 0.094 12.7 0.4 2.3 2 1 0 2 2 2 0 Spindle pole body component Spc42p MEA1 PF06910.11 EKX33035.1 - 0.0038 17.9 1.1 0.0048 17.5 1.1 1.2 1 0 0 1 1 1 1 Male enhanced antigen 1 (MEA1) PARP PF00644.20 EKX33036.1 - 1.3e-23 83.7 0.0 3.5e-22 79.0 0.0 2.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain BofC_C PF08955.10 EKX33037.1 - 0.078 13.0 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 BofC C-terminal domain Mpv17_PMP22 PF04117.12 EKX33038.1 - 4.1e-08 33.3 0.2 9.3e-08 32.2 0.2 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family SET PF00856.28 EKX33039.1 - 2.8e-14 53.9 0.0 8.6e-14 52.3 0.0 1.8 1 1 0 1 1 1 1 SET domain PLD_C PF12357.8 EKX33040.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Phospholipase D C terminal Patched PF02460.18 EKX33041.1 - 5.2e-29 100.9 26.2 5.9e-19 67.7 7.0 2.5 3 0 0 3 3 3 2 Patched family Sterol-sensing PF12349.8 EKX33041.1 - 6.6e-14 52.0 7.9 6.6e-14 52.0 7.9 2.7 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 EKX33041.1 - 0.042 12.8 25.9 0.37 9.7 7.0 2.3 2 0 0 2 2 2 0 MMPL family ABC_tran PF00005.27 EKX33042.1 - 4.1e-09 37.1 0.2 1.6e-08 35.2 0.1 1.9 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 EKX33042.1 - 4e-05 23.6 0.0 5.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EKX33042.1 - 0.00043 20.0 0.7 0.0012 18.6 0.7 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 EKX33042.1 - 0.00086 18.9 0.1 0.0014 18.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EKX33042.1 - 0.0012 19.4 0.1 0.0017 18.9 0.1 1.2 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EKX33042.1 - 0.0027 17.8 0.1 0.0045 17.1 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 EKX33042.1 - 0.0051 16.4 0.1 0.0076 15.9 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EKX33042.1 - 0.0082 16.1 0.1 0.014 15.3 0.1 1.4 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 EKX33042.1 - 0.013 16.1 0.1 0.07 13.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EKX33042.1 - 0.015 15.7 0.1 0.026 14.9 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EKX33042.1 - 0.03 14.6 0.1 0.051 13.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EKX33042.1 - 0.039 13.7 0.0 0.065 13.0 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.12 EKX33042.1 - 0.052 12.8 0.2 0.083 12.2 0.2 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 EKX33042.1 - 0.095 12.4 0.2 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EKX33042.1 - 0.13 12.5 0.6 0.2 11.9 0.6 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EKX33042.1 - 0.13 12.7 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 EKX33042.1 - 0.16 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class PDZ_4 PF17816.1 EKX33044.1 - 0.086 13.2 0.1 0.14 12.6 0.1 1.3 1 0 0 1 1 1 0 PDZ domain DivIC PF04977.15 EKX33044.1 - 0.21 11.4 1.0 0.47 10.3 0.9 1.6 1 1 0 1 1 1 0 Septum formation initiator RCC1 PF00415.18 EKX33045.1 - 1.1e-78 259.7 18.2 1.2e-16 61.1 0.5 6.3 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX33045.1 - 4.6e-34 115.5 35.3 2.9e-10 39.7 0.2 8.9 10 0 0 10 10 10 7 Regulator of chromosome condensation (RCC1) repeat Kelch_2 PF07646.15 EKX33045.1 - 0.1 12.6 0.9 17 5.5 0.0 3.0 3 0 0 3 3 3 0 Kelch motif DUF745 PF05335.13 EKX33046.1 - 3.7 7.2 14.2 0.5 10.1 1.9 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF745) MRAP PF15183.6 EKX33047.1 - 0.13 12.2 0.1 0.16 11.9 0.1 1.1 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family Peptidase_C97 PF05903.14 EKX33048.1 - 2.3e-33 115.1 0.0 2.8e-33 114.9 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain NUDIX PF00293.28 EKX33049.1 - 1.9e-11 44.1 0.5 2.8e-11 43.6 0.2 1.5 2 0 0 2 2 2 1 NUDIX domain KCNQ2_u3 PF16642.5 EKX33050.1 - 0.04 14.9 0.1 0.082 13.9 0.1 1.5 1 0 0 1 1 1 0 Unstructured region on Potassium channel subunit alpha KvLQT2 Lig_chan PF00060.26 EKX33051.1 - 7.6e-09 35.6 0.0 1.5e-08 34.6 0.0 1.4 1 1 0 1 1 1 1 Ligand-gated ion channel Ferric_reduct PF01794.19 EKX33051.1 - 0.023 14.8 0.3 0.064 13.4 0.0 1.8 2 0 0 2 2 2 0 Ferric reductase like transmembrane component PGA2 PF07543.12 EKX33051.1 - 0.029 14.3 1.4 0.049 13.6 1.4 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 CENP-B_dimeris PF09026.10 EKX33051.1 - 0.64 10.5 6.3 1.2 9.6 6.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 EKX33051.1 - 7.1 5.8 6.5 12 5.1 6.5 1.2 1 0 0 1 1 1 0 NOA36 protein NT5C PF06941.12 EKX33053.1 - 1.7e-23 83.4 0.3 2.1e-23 83.1 0.3 1.0 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD_2 PF13419.6 EKX33053.1 - 0.0032 17.6 0.0 0.0073 16.4 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 EKX33053.1 - 0.088 13.2 0.3 0.27 11.6 0.2 1.9 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Actin PF00022.19 EKX33055.1 - 3.8e-126 421.0 0.1 3.7e-76 256.3 0.0 2.6 1 1 1 2 2 2 2 Actin DUF4215 PF13948.6 EKX33056.1 - 6e-09 36.2 5.9 6e-09 36.2 5.9 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4215) Ank_4 PF13637.6 EKX33057.1 - 1e-23 83.3 0.8 7e-06 26.5 0.0 4.9 4 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX33057.1 - 2.6e-23 82.4 11.4 1.5e-06 28.7 0.1 4.1 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX33057.1 - 4e-14 52.5 4.3 0.0011 19.3 0.0 6.4 4 2 3 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX33057.1 - 5.9e-12 44.7 0.4 0.045 14.3 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 EKX33057.1 - 2e-08 34.3 2.3 0.00067 20.0 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat RTP1_C2 PF10304.9 EKX33057.1 - 0.019 14.7 2.4 0.77 9.5 0.0 3.2 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 2 Keratin_B2 PF01500.17 EKX33058.1 - 0.027 14.5 11.6 0.58 10.1 12.1 2.7 1 1 1 2 2 2 0 Keratin, high sulfur B2 protein Keratin_B2_2 PF13885.6 EKX33058.1 - 0.21 11.6 22.9 0.14 12.1 16.0 3.4 4 0 0 4 4 4 0 Keratin, high sulfur B2 protein DUF347 PF03988.12 EKX33060.1 - 0.11 12.8 0.4 21 5.4 0.1 2.2 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) CWC25 PF12542.8 EKX33060.1 - 3.8 8.5 6.5 38 5.3 0.8 3.0 2 0 0 2 2 2 0 Pre-mRNA splicing factor Pkinase PF00069.25 EKX33062.1 - 1.9e-08 34.0 0.1 0.0011 18.4 0.1 3.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EKX33062.1 - 0.0017 17.7 0.0 0.71 9.1 0.0 2.5 1 1 0 2 2 2 2 Protein tyrosine kinase Exonuc_VII_L PF02601.15 EKX33062.1 - 0.85 9.1 13.8 1.4 8.4 9.2 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit FAM76 PF16046.5 EKX33062.1 - 2 7.7 10.7 4 6.7 10.7 1.5 1 0 0 1 1 1 0 FAM76 protein WD40 PF00400.32 EKX33063.1 - 2.4e-13 50.3 4.0 2.3e-09 37.7 0.1 2.0 2 0 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.8 EKX33063.1 - 0.2 10.3 2.3 3.2 6.3 0.1 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Yip1 PF04893.17 EKX33064.1 - 0.0029 17.3 0.4 0.004 16.9 0.4 1.2 1 0 0 1 1 1 1 Yip1 domain Rick_17kDa_Anti PF05433.15 EKX33064.1 - 0.015 15.1 8.2 0.03 14.2 8.2 1.5 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 EKX33064.1 - 0.1 12.6 11.6 0.21 11.6 11.6 1.6 1 1 0 1 1 1 0 Glycine zipper Mucin15 PF15672.5 EKX33064.1 - 0.13 11.7 3.9 0.089 12.3 2.1 1.3 1 1 0 1 1 1 0 Cell-membrane associated Mucin15 Beta-APP PF03494.13 EKX33064.1 - 9.8 6.1 10.3 17 5.3 10.3 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) HTH_Tnp_Tc5 PF03221.16 EKX33067.1 - 4e-05 23.6 0.1 0.00013 21.9 0.1 2.0 1 1 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 EKX33067.1 - 0.00021 20.9 0.4 0.00037 20.1 0.4 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 EKX33067.1 - 0.0024 17.6 0.1 0.0044 16.8 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain F-box-like_2 PF13013.6 EKX33067.1 - 0.059 13.3 0.2 0.1 12.6 0.2 1.4 1 0 0 1 1 1 0 F-box-like domain HTH_23 PF13384.6 EKX33067.1 - 0.17 11.7 0.1 0.3 10.9 0.1 1.4 1 0 0 1 1 1 0 Homeodomain-like domain SNF2_N PF00176.23 EKX33068.1 - 1.4e-36 126.0 7.1 1.4e-35 122.7 4.2 2.7 1 1 1 2 2 2 2 SNF2 family N-terminal domain DEAD PF00270.29 EKX33068.1 - 0.00084 19.1 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EKX33068.1 - 0.01 15.9 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Ank_2 PF12796.7 EKX33069.1 - 3.4e-25 88.4 0.0 2.4e-11 44.1 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX33069.1 - 1.1e-22 80.0 0.0 3.8e-05 24.2 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX33069.1 - 8e-15 54.7 1.6 0.042 14.2 0.1 5.5 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX33069.1 - 9.8e-12 44.0 0.1 0.18 12.4 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 EKX33069.1 - 2.7e-08 33.9 0.1 0.3 11.6 0.0 5.0 6 0 0 6 6 6 2 Ankyrin repeat LtuA PF17446.2 EKX33069.1 - 0.014 15.8 0.0 6.2 7.3 0.0 3.8 3 1 1 4 4 4 0 Late transcription unit A VHS PF00790.19 EKX33069.1 - 0.21 11.4 1.3 48 3.8 0.0 3.9 5 0 0 5 5 5 0 VHS domain Ins_beta PF03488.14 EKX33069.1 - 0.71 9.9 6.2 12 6.0 0.0 4.2 5 0 0 5 5 5 0 Nematode insulin-related peptide beta type OrfB_Zn_ribbon PF07282.11 EKX33069.1 - 1.2 9.1 5.2 3.3 7.7 0.2 3.1 2 2 1 3 3 3 0 Putative transposase DNA-binding domain Tsc35 PF15079.6 EKX33071.1 - 0.00025 20.7 2.5 0.00044 19.9 2.5 1.4 1 0 0 1 1 1 1 Testis-specific protein 35 zf-CCHC PF00098.23 EKX33071.1 - 0.00025 21.0 1.3 0.00025 21.0 1.3 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.6 EKX33071.1 - 0.00099 18.9 0.6 0.0024 17.7 0.6 1.7 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.8 EKX33071.1 - 0.002 18.5 0.3 0.0066 16.8 0.3 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RVP_2 PF08284.11 EKX33071.1 - 0.014 15.2 0.5 3 7.6 0.0 2.3 1 1 1 2 2 2 0 Retroviral aspartyl protease Retrotrans_gag PF03732.17 EKX33071.1 - 0.035 14.4 1.2 0.72 10.2 0.0 2.7 2 1 0 2 2 2 0 Retrotransposon gag protein Gag_p24 PF00607.20 EKX33071.1 - 0.043 13.7 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 gag gene protein p24 (core nucleocapsid protein) zf-C2H2_10 PF16588.5 EKX33071.1 - 0.18 11.5 1.5 0.5 10.1 1.5 1.8 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_4 PF14392.6 EKX33071.1 - 0.19 11.5 0.6 0.44 10.3 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle Asp_protease_2 PF13650.6 EKX33071.1 - 0.2 12.3 0.0 0.4 11.4 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease YabA PF06156.13 EKX33071.1 - 0.28 11.9 11.3 0.52 11.0 4.1 3.0 2 1 1 3 3 3 0 Initiation control protein YabA FUSC PF04632.12 EKX33071.1 - 0.35 9.3 2.4 0.65 8.5 2.4 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-CCHC_2 PF13696.6 EKX33071.1 - 0.48 10.3 2.9 2.6 7.9 2.6 2.2 2 0 0 2 2 2 0 Zinc knuckle DUF5101 PF17031.5 EKX33071.1 - 1.2 9.3 6.7 4.3 7.5 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5101) Cuticle_3 PF11018.8 EKX33072.1 - 1.5e-11 44.8 6.0 0.013 15.8 1.6 4.5 1 1 1 2 2 2 2 Pupal cuticle protein C1 Tymo_coat PF00983.18 EKX33072.1 - 0.072 12.9 2.6 34 4.2 0.1 4.8 3 2 0 3 3 3 0 Tymovirus coat protein AAA_11 PF13086.6 EKX33073.1 - 0.00015 21.6 0.4 0.00041 20.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EKX33073.1 - 0.0026 18.1 0.0 0.0073 16.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EKX33073.1 - 0.0063 16.9 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EKX33073.1 - 0.0083 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region MeaB PF03308.16 EKX33073.1 - 0.014 14.4 0.0 0.042 12.8 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EKX33073.1 - 0.025 14.3 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EKX33073.1 - 0.044 13.4 0.1 0.13 11.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EKX33073.1 - 0.056 13.4 0.0 0.82 9.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EKX33073.1 - 0.11 13.0 0.1 0.31 11.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 EKX33073.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Cuticle_3 PF11018.8 EKX33074.1 - 6.9e-12 46.0 1.3 0.0027 18.0 0.1 4.0 1 1 2 3 3 3 3 Pupal cuticle protein C1 Drf_FH1 PF06346.12 EKX33074.1 - 0.29 10.8 0.8 21 4.8 0.1 2.8 1 1 2 3 3 3 0 Formin Homology Region 1 Sin3_corepress PF08295.12 EKX33075.1 - 2.5e-37 126.9 0.2 5.2e-37 125.9 0.2 1.6 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.21 EKX33075.1 - 6.7e-36 122.2 6.2 5.3e-18 64.9 0.2 3.9 3 1 1 4 4 4 3 Paired amphipathic helix repeat PAS_9 PF13426.7 EKX33076.1 - 1e-06 29.0 0.0 0.0032 17.7 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 EKX33076.1 - 9.4e-05 22.4 0.0 0.035 14.1 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 EKX33076.1 - 0.0023 18.2 0.0 0.82 10.0 0.0 2.4 2 0 0 2 2 2 2 PAS fold Chromo PF00385.24 EKX33077.1 - 1.6e-05 24.7 0.1 1.8e-05 24.5 0.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_11 PF13086.6 EKX33079.1 - 6.8e-05 22.8 0.0 0.00017 21.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EKX33079.1 - 0.0013 19.0 0.0 0.0037 17.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EKX33079.1 - 0.0026 18.2 0.0 0.0079 16.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 EKX33079.1 - 0.013 14.5 0.0 0.038 13.0 0.0 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EKX33079.1 - 0.014 15.9 0.0 0.042 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EKX33079.1 - 0.022 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Nucleic_acid_bd PF13820.6 EKX33079.1 - 0.03 14.2 0.0 1.4 8.7 0.0 2.8 3 0 0 3 3 3 0 Putative nucleic acid-binding region AAA_25 PF13481.6 EKX33079.1 - 0.032 13.8 0.1 0.21 11.2 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 EKX33079.1 - 0.033 13.9 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 EKX33079.1 - 0.067 13.2 0.0 0.23 11.5 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.29 EKX33080.1 - 5.9e-96 318.0 0.0 3.5e-47 160.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EKX33080.1 - 4.5e-28 96.8 9.4 6.5e-15 54.7 0.8 3.3 3 0 0 3 3 3 2 AAA+ lid domain CDC48_N PF02359.18 EKX33080.1 - 4.1e-22 78.2 3.3 5.1e-22 77.9 1.4 2.3 3 0 0 3 3 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 EKX33080.1 - 1.2e-13 51.1 0.0 2.4e-05 24.1 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EKX33080.1 - 5.8e-13 49.3 0.0 6.1e-06 26.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EKX33080.1 - 1.2e-11 45.3 0.1 0.00089 19.7 0.0 3.9 2 2 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 EKX33080.1 - 2.5e-11 43.9 0.0 9.6e-06 25.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 EKX33080.1 - 1.4e-10 40.8 0.0 2.7e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.14 EKX33080.1 - 9.2e-10 38.7 0.1 0.00033 20.7 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EKX33080.1 - 1.8e-08 34.5 0.0 0.0042 17.1 0.0 2.9 2 1 1 3 3 2 2 AAA domain TIP49 PF06068.13 EKX33080.1 - 2.3e-08 33.7 0.2 0.0022 17.2 0.0 2.7 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_22 PF13401.6 EKX33080.1 - 3.1e-08 34.0 0.2 0.086 13.1 0.0 4.2 2 2 1 3 3 3 2 AAA domain Mg_chelatase PF01078.21 EKX33080.1 - 1.9e-07 30.7 0.3 0.02 14.3 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Vps4_C PF09336.10 EKX33080.1 - 3.8e-07 30.0 0.5 1.8e-05 24.6 0.1 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.22 EKX33080.1 - 4.8e-07 30.1 0.0 0.0051 17.2 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 EKX33080.1 - 1e-06 29.4 0.0 0.043 14.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EKX33080.1 - 6.2e-06 26.1 0.0 0.078 12.7 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein ABC_tran PF00005.27 EKX33080.1 - 6.5e-06 26.7 0.1 0.013 16.0 0.0 3.0 2 1 0 2 2 2 1 ABC transporter ATPase_2 PF01637.18 EKX33080.1 - 6.8e-06 26.2 0.1 0.17 11.8 0.0 3.5 3 1 0 3 3 2 2 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 EKX33080.1 - 7.5e-06 25.9 0.0 0.099 12.5 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein Viral_helicase1 PF01443.18 EKX33080.1 - 1.9e-05 24.5 0.0 0.0021 17.8 0.0 2.7 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 EKX33080.1 - 1.9e-05 25.1 0.0 0.2 12.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 EKX33080.1 - 4.3e-05 22.9 0.0 0.39 10.0 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin ATPase PF06745.13 EKX33080.1 - 4.4e-05 22.9 0.1 1.9 7.8 0.0 3.5 3 0 0 3 3 3 1 KaiC Parvo_NS1 PF01057.17 EKX33080.1 - 5.7e-05 22.3 0.0 0.029 13.5 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 EKX33080.1 - 6.5e-05 22.5 0.0 0.12 11.9 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 EKX33080.1 - 6.9e-05 22.8 0.1 0.21 11.5 0.0 3.6 3 1 1 4 4 4 1 NACHT domain AAA_24 PF13479.6 EKX33080.1 - 9.8e-05 22.2 0.0 0.24 11.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EKX33080.1 - 0.00017 21.9 0.0 0.22 11.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 EKX33080.1 - 0.00027 20.9 0.0 0.31 11.0 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 EKX33080.1 - 0.00028 20.1 0.0 0.2 10.8 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain DUF815 PF05673.13 EKX33080.1 - 0.00037 19.7 0.0 0.019 14.1 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NTPase_1 PF03266.15 EKX33080.1 - 0.00044 20.2 2.0 2.2 8.2 0.0 4.9 4 1 1 5 5 5 1 NTPase Sigma54_activat PF00158.26 EKX33080.1 - 0.00052 19.7 0.0 1.5 8.5 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain ResIII PF04851.15 EKX33080.1 - 0.00071 19.6 0.0 0.16 12.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Rad17 PF03215.15 EKX33080.1 - 0.0011 19.0 0.1 1 9.3 0.0 3.2 3 1 0 3 3 3 1 Rad17 P-loop domain AAA_3 PF07726.11 EKX33080.1 - 0.0012 18.7 0.0 2 8.3 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EKX33080.1 - 0.002 17.6 0.1 2.2 7.7 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_25 PF13481.6 EKX33080.1 - 0.0031 17.1 3.0 3.6 7.1 0.0 4.2 3 2 0 4 4 4 1 AAA domain DUF2075 PF09848.9 EKX33080.1 - 0.0031 16.8 0.0 1.3 8.2 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 EKX33080.1 - 0.0072 16.4 0.0 7 6.8 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 EKX33080.1 - 0.01 16.2 0.5 18 5.7 0.0 3.6 3 1 0 4 4 3 0 AAA domain AAA_11 PF13086.6 EKX33080.1 - 0.011 15.5 0.2 5.4 6.7 0.0 2.7 3 0 0 3 3 2 0 AAA domain SKI PF01202.22 EKX33080.1 - 0.041 14.0 0.0 12 6.0 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase Zot PF05707.12 EKX33080.1 - 0.057 13.1 0.0 0.72 9.5 0.0 2.4 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_30 PF13604.6 EKX33080.1 - 0.098 12.4 0.1 19 4.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 EKX33080.1 - 0.11 11.9 0.1 26 4.2 0.0 3.3 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_23 PF13476.6 EKX33080.1 - 0.16 12.5 0.0 17 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain EF-hand_7 PF13499.6 EKX33081.1 - 6.3e-05 23.4 0.1 0.00013 22.4 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX33081.1 - 0.011 15.6 0.3 0.77 9.8 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain SPARC_Ca_bdg PF10591.9 EKX33081.1 - 0.051 13.9 0.1 0.065 13.6 0.1 1.4 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 EKX33081.1 - 0.12 12.3 0.3 1.1 9.2 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_7 PF13499.6 EKX33084.1 - 1.2e-24 86.5 11.5 7.7e-11 42.3 0.2 3.7 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EKX33084.1 - 8.3e-24 82.0 12.9 9.4e-06 24.9 0.0 5.2 5 0 0 5 5 5 4 EF hand EF-hand_1 PF00036.32 EKX33084.1 - 2.7e-23 79.7 13.4 7.7e-05 22.0 0.1 5.7 6 1 1 7 7 7 4 EF hand EF-hand_6 PF13405.6 EKX33084.1 - 6.8e-20 69.2 14.6 0.00026 20.7 0.1 5.8 6 0 0 6 6 6 4 EF-hand domain EF-hand_8 PF13833.6 EKX33084.1 - 7.5e-17 60.9 12.1 3.6e-07 29.9 0.1 5.2 3 3 2 5 5 5 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX33084.1 - 6.7e-16 58.6 0.6 3.5e-07 30.5 0.0 3.3 3 1 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 EKX33084.1 - 0.00082 19.5 2.8 5.6 7.2 1.2 4.5 4 1 0 4 4 3 1 Dockerin type I domain Ferritin PF00210.24 EKX33084.1 - 0.0037 17.2 1.0 0.67 9.9 0.1 2.4 2 0 0 2 2 2 2 Ferritin-like domain Excalibur PF05901.11 EKX33084.1 - 0.011 16.3 0.4 14 6.4 0.0 4.1 4 0 0 4 4 4 0 Excalibur calcium-binding domain EF-hand_4 PF12763.7 EKX33084.1 - 0.053 13.5 1.8 1.2 9.1 0.0 2.9 3 0 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand DUF494 PF04361.13 EKX33084.1 - 0.095 12.6 0.1 2 8.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF494) Dimerisation PF08100.11 EKX33084.1 - 0.14 12.2 0.1 3.7 7.7 0.0 2.7 3 0 0 3 3 3 0 Dimerisation domain ApoLp-III PF07464.11 EKX33084.1 - 0.18 11.9 1.8 0.56 10.3 0.1 2.3 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Abhydrolase_3 PF07859.13 EKX33086.1 - 1.9e-05 24.6 0.0 3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EKX33086.1 - 6.8e-05 22.3 0.0 9.5e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EKX33086.1 - 0.00057 20.6 0.2 0.00095 19.8 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EKX33086.1 - 0.023 14.8 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.20 EKX33086.1 - 0.078 12.6 0.0 0.16 11.6 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 EKX33086.1 - 0.19 11.4 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative esterase PDCD7 PF16021.5 EKX33086.1 - 1.8 7.6 6.8 0.31 10.1 2.7 1.7 2 0 0 2 2 2 0 Programmed cell death protein 7 Acyltransferase PF01553.21 EKX33087.1 - 0.00017 21.2 0.0 0.00017 21.2 0.0 1.0 1 0 0 1 1 1 1 Acyltransferase DAGAT PF03982.13 EKX33087.1 - 0.0003 19.8 0.0 0.00031 19.8 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase CLASP_N PF12348.8 EKX33088.1 - 1.1e-28 100.4 1.8 1.4e-13 50.9 0.3 3.3 3 0 0 3 3 3 3 CLASP N terminal HEAT_2 PF13646.6 EKX33088.1 - 4.8e-14 52.5 20.8 0.0058 17.0 0.1 8.2 5 3 2 8 8 8 4 HEAT repeats HEAT_EZ PF13513.6 EKX33088.1 - 8.8e-09 35.7 10.3 0.2 12.2 0.1 6.2 4 1 1 5 5 5 3 HEAT-like repeat HEAT PF02985.22 EKX33088.1 - 9.5e-09 34.8 22.4 1.5 9.3 0.1 10.2 10 0 0 10 10 10 3 HEAT repeat Cnd1 PF12717.7 EKX33088.1 - 1.9e-05 24.8 0.6 0.042 13.9 0.0 4.4 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EKX33088.1 - 0.0021 18.6 0.0 17 6.1 0.0 4.7 5 1 2 7 7 7 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 EKX33088.1 - 0.015 15.5 1.8 4.4 7.5 0.1 4.2 4 2 1 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Dopey_N PF04118.14 EKX33088.1 - 0.04 13.0 0.4 0.56 9.3 0.1 2.6 2 1 0 2 2 2 0 Dopey, N-terminal RasGEF_N_2 PF14663.6 EKX33088.1 - 0.088 13.2 1.4 17 5.8 0.0 4.4 4 1 1 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Arm PF00514.23 EKX33088.1 - 0.18 11.9 0.4 1.9 8.7 0.2 2.9 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat DUF5578 PF17741.1 EKX33088.1 - 0.39 10.1 3.5 11 5.3 0.0 3.9 4 0 0 4 4 4 0 Family of unknown function (DUF5578) Sec7_N PF12783.7 EKX33088.1 - 0.82 9.6 6.4 13 5.6 0.0 3.5 3 2 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Vitellogenin_N PF01347.22 EKX33089.1 - 0.0038 15.7 0.2 0.12 10.7 0.1 2.0 1 1 1 2 2 2 2 Lipoprotein amino terminal region ATG16 PF08614.11 EKX33092.1 - 3.5e-06 27.4 7.7 3.5e-06 27.4 7.7 4.5 2 2 2 4 4 4 1 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 EKX33092.1 - 0.0057 16.7 10.6 0.0057 16.7 10.6 6.1 5 1 1 6 6 6 2 TPR/MLP1/MLP2-like protein Noelin-1 PF12308.8 EKX33092.1 - 0.04 13.9 0.7 0.04 13.9 0.7 4.0 2 2 2 4 4 4 0 Neurogenesis glycoprotein Inhibitor_I71 PF12628.7 EKX33092.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor BING4CT PF08149.11 EKX33092.1 - 4 7.3 4.8 0.7 9.7 0.1 2.2 2 0 0 2 2 2 0 BING4CT (NUC141) domain Baculo_PEP_C PF04513.12 EKX33092.1 - 8.2 6.5 10.0 10 6.2 1.3 3.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Baculo_PEP_C PF04513.12 EKX33093.1 - 0.58 10.2 4.1 3.7 7.6 0.3 3.4 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus TIG PF01833.24 EKX33094.1 - 5.6e-159 516.7 71.0 5.5e-16 58.4 1.0 13.2 13 0 0 13 13 13 13 IPT/TIG domain RHD_dimer PF16179.5 EKX33094.1 - 3.5e-06 27.0 0.0 9.2 6.3 0.0 7.8 9 2 0 9 9 9 1 Rel homology dimerisation domain TIG_plexin PF17960.1 EKX33094.1 - 0.0041 17.1 1.6 2 8.4 0.0 4.8 6 0 0 6 6 6 1 TIG domain SR-25 PF10500.9 EKX33094.1 - 0.0073 15.9 13.3 0.013 15.1 13.3 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Qn_am_d_aIII PF09099.10 EKX33094.1 - 0.35 11.3 6.8 4.2 7.8 0.1 4.8 5 0 0 5 5 5 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III AF-4 PF05110.13 EKX33094.1 - 0.93 7.5 14.5 1.3 7.0 14.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Phostensin_N PF13916.6 EKX33095.1 - 0.0045 17.3 0.1 0.0082 16.5 0.1 1.4 1 0 0 1 1 1 1 PP1-regulatory protein, Phostensin N-terminal MFS_1 PF07690.16 EKX33096.1 - 3.7e-37 128.1 22.4 4.5e-29 101.5 10.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EKX33096.1 - 1.7e-09 37.1 4.6 1.7e-09 37.1 4.6 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 EKX33096.1 - 0.001 17.7 13.3 0.035 12.7 2.9 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein TMEM51 PF15345.6 EKX33096.1 - 0.22 11.3 0.1 0.37 10.6 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Polysacc_synt PF01943.17 EKX33096.1 - 0.22 10.8 5.7 3.9 6.8 0.4 3.0 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein ING PF12998.7 EKX33098.1 - 0.031 14.9 0.4 1.9 9.1 0.2 2.4 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding ICA69 PF04629.14 EKX33098.1 - 0.17 12.2 5.5 0.095 13.0 3.3 1.7 2 0 0 2 2 2 0 Islet cell autoantigen ICA69, C-terminal domain Myb_DNA-binding PF00249.31 EKX33099.1 - 1.1e-05 25.6 0.0 0.00018 21.6 0.0 2.2 1 1 0 1 1 1 1 Myb-like DNA-binding domain TEA PF01285.18 EKX33099.1 - 0.0058 16.7 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 TEA/ATTS domain CENP-L PF13092.6 EKX33099.1 - 0.061 13.5 2.0 2.4 8.4 2.0 2.3 1 1 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 DUF2333 PF10095.9 EKX33100.1 - 0.12 11.4 0.1 0.31 10.0 0.2 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2333) Myb_DNA-binding PF00249.31 EKX33102.1 - 5.6e-07 29.6 0.2 2.5e-06 27.6 0.0 2.2 2 1 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EKX33103.1 - 2.7e-08 33.9 0.1 1.8e-07 31.3 0.1 2.0 1 1 0 1 1 1 1 Myb-like DNA-binding domain TEA PF01285.18 EKX33103.1 - 0.03 14.4 0.0 0.071 13.2 0.0 1.6 1 1 0 1 1 1 0 TEA/ATTS domain HupE_UreJ_2 PF13795.6 EKX33104.1 - 0.08 12.6 1.0 1 9.0 0.2 2.3 2 0 0 2 2 2 0 HupE / UreJ protein 7tm_7 PF08395.12 EKX33104.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.4 1 1 0 1 1 1 0 7tm Chemosensory receptor YebG PF07130.12 EKX33105.1 - 0.4 10.5 5.3 0.92 9.4 0.0 3.7 3 1 1 4 4 4 0 YebG protein Abhydrolase_6 PF12697.7 EKX33106.1 - 0.028 15.0 0.1 0.032 14.8 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family CD225 PF04505.12 EKX33108.1 - 0.021 15.0 2.3 2.1 8.6 0.4 2.4 2 0 0 2 2 2 0 Interferon-induced transmembrane protein Alpha_kinase PF02816.18 EKX33109.1 - 2e-24 86.8 1.3 2.7e-24 86.3 1.3 1.3 1 0 0 1 1 1 1 Alpha-kinase family DTW PF03942.15 EKX33110.1 - 2.3e-30 105.8 0.0 6.7e-30 104.3 0.0 1.6 1 1 0 1 1 1 1 DTW domain Putative_PNPOx PF01243.20 EKX33111.1 - 5e-05 23.4 0.0 0.068 13.4 0.0 2.4 1 1 1 2 2 2 2 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 EKX33111.1 - 0.0077 15.8 0.0 0.25 10.9 0.0 2.2 1 1 1 2 2 2 2 Pyridoxamine 5'-phosphate oxidase like Globin PF00042.22 EKX33112.1 - 0.00011 22.8 0.1 0.00097 19.7 0.1 2.1 1 1 0 1 1 1 1 Globin Transmemb_17 PF09799.9 EKX33113.1 - 2e-23 83.0 10.9 2e-23 83.0 10.9 2.1 1 1 1 2 2 2 1 Predicted membrane protein U-box PF04564.15 EKX33114.1 - 1.2e-19 70.2 0.0 1.4e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX33114.1 - 0.0057 16.4 0.1 0.0083 15.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Pkinase_Tyr PF07714.17 EKX33115.1 - 7.4e-43 146.7 0.0 8.3e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX33115.1 - 8e-17 61.5 0.0 9.8e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Ribosomal_60s PF00428.19 EKX33116.1 - 2.8e-17 63.1 5.3 3.4e-17 62.8 5.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Totivirus_coat PF05518.11 EKX33116.1 - 1.4 6.8 3.6 1.6 6.7 3.6 1.1 1 0 0 1 1 1 0 Totivirus coat protein RETICULATA-like PF11891.8 EKX33117.1 - 7.1e-41 140.0 0.0 1e-40 139.5 0.0 1.2 1 0 0 1 1 1 1 Protein RETICULATA-related Bac_rhodopsin PF01036.18 EKX33118.1 - 2.5e-22 79.5 12.1 3.8e-22 79.0 12.1 1.2 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein TPR_1 PF00515.28 EKX33119.1 - 1.2e-39 132.5 9.2 2.3e-05 24.0 0.0 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 EKX33119.1 - 2.9e-36 120.6 7.8 6.2e-05 22.9 0.0 9.0 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 EKX33119.1 - 1.1e-34 117.9 10.7 3.4e-05 23.4 0.0 8.5 5 2 3 8 8 8 7 TPR repeat TPR_2 PF07719.17 EKX33119.1 - 5.4e-34 113.6 11.8 1.8e-05 24.5 0.0 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.6 EKX33119.1 - 4.2e-27 92.5 4.7 0.0074 16.6 0.0 9.4 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 EKX33119.1 - 5.9e-25 87.4 9.8 3.2e-07 30.6 0.1 5.4 4 1 1 5 5 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 EKX33119.1 - 2.2e-21 74.7 13.0 0.0021 18.7 0.0 8.7 3 3 5 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 EKX33119.1 - 4.3e-19 68.8 12.0 0.00011 22.7 1.0 5.6 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 EKX33119.1 - 1.8e-18 65.1 7.2 0.0045 16.9 0.0 7.2 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 EKX33119.1 - 2.4e-17 63.3 17.9 5e-06 27.1 0.6 4.9 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX33119.1 - 1.2e-13 50.5 25.7 0.015 15.1 0.1 6.8 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_6 PF13174.6 EKX33119.1 - 1.2e-10 41.3 10.2 1.6 9.6 0.1 6.7 7 0 0 7 7 6 4 Tetratricopeptide repeat Glyco_transf_41 PF13844.6 EKX33119.1 - 8.1e-08 31.1 0.4 7.6e-07 27.9 0.2 2.0 1 1 1 2 2 2 1 Glycosyl transferase family 41 TPR_15 PF13429.6 EKX33119.1 - 3e-07 30.0 4.8 0.00013 21.2 0.4 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 EKX33119.1 - 6.3e-05 23.4 7.5 0.024 15.1 0.1 3.5 3 1 0 3 3 3 2 Bacterial transcriptional activator domain TPR_MalT PF17874.1 EKX33119.1 - 0.00028 20.4 2.1 0.047 13.1 0.2 3.2 2 2 1 3 3 3 1 MalT-like TPR region TPR_9 PF13371.6 EKX33119.1 - 0.00035 20.7 8.0 0.0076 16.4 0.2 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 EKX33119.1 - 0.00045 19.8 6.1 0.52 9.7 0.2 3.9 4 1 0 4 4 4 1 Est1 DNA/RNA binding domain ANAPC3 PF12895.7 EKX33119.1 - 0.0034 17.6 3.4 2.2 8.6 0.1 3.5 2 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 FAT PF02259.23 EKX33119.1 - 0.014 14.7 0.0 0.15 11.3 0.0 2.3 2 0 0 2 2 2 0 FAT domain TPR_20 PF14561.6 EKX33119.1 - 0.019 15.3 2.0 1.7 9.1 0.1 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Coatomer_E PF04733.14 EKX33119.1 - 0.033 13.6 0.2 2.3 7.6 0.0 2.6 2 0 0 2 2 2 0 Coatomer epsilon subunit DUF3856 PF12968.7 EKX33119.1 - 0.084 12.9 3.6 2.1 8.4 0.1 3.7 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.6 EKX33119.1 - 0.12 12.4 0.7 2.8 8.1 0.0 3.4 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 EKX33119.1 - 0.13 12.3 16.8 0.88 9.7 0.5 5.7 3 2 3 6 6 5 0 MIT (microtubule interacting and transport) domain ANAPC5 PF12862.7 EKX33119.1 - 0.25 11.4 1.8 20 5.4 0.2 4.1 3 2 0 4 4 4 0 Anaphase-promoting complex subunit 5 NARP1 PF12569.8 EKX33119.1 - 2 7.2 11.0 0.67 8.8 0.1 2.8 3 1 0 3 3 2 0 NMDA receptor-regulated protein 1 FA_desaturase PF00487.24 EKX33119.1 - 2.5 7.9 5.7 0.5 10.2 2.0 1.7 2 0 0 2 2 2 0 Fatty acid desaturase TPR_21 PF09976.9 EKX33119.1 - 8.9 6.0 10.6 52 3.5 0.1 3.8 2 2 1 3 3 3 0 Tetratricopeptide repeat-like domain ER PF01133.17 EKX33120.1 - 1.2e-37 127.9 0.0 1.3e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary dsDNA_bind PF01984.20 EKX33121.1 - 5.3e-16 58.9 7.2 2.5e-15 56.7 7.2 1.9 1 1 0 1 1 1 1 Double-stranded DNA-binding domain WD40 PF00400.32 EKX33122.1 - 2.3e-18 66.2 21.3 0.029 15.3 0.3 9.8 10 2 1 11 11 11 6 WD domain, G-beta repeat FHA PF00498.26 EKX33122.1 - 3.7e-14 52.8 0.1 7.8e-14 51.8 0.1 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EKX33122.1 - 3.3e-08 33.7 0.0 2e-06 28.0 0.0 2.6 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain ANAPC4_WD40 PF12894.7 EKX33122.1 - 1.6e-07 31.5 0.1 0.0023 18.2 0.0 4.5 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain HELP PF03451.14 EKX33122.1 - 5.7e-07 29.3 0.1 1.6e-06 27.8 0.1 1.8 1 1 0 1 1 1 1 HELP motif Cytochrom_D1 PF02239.16 EKX33122.1 - 0.0053 15.3 0.5 2.6 6.5 0.1 2.5 2 0 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.12 EKX33122.1 - 0.019 14.9 0.0 0.14 12.1 0.0 2.6 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Hira PF07569.11 EKX33122.1 - 0.14 11.9 0.0 8 6.1 0.0 3.3 3 1 0 3 3 3 0 TUP1-like enhancer of split Nucleoporin_N PF08801.11 EKX33122.1 - 0.15 10.8 2.7 6.8 5.3 0.2 3.2 2 1 1 3 3 3 0 Nup133 N terminal like HAT_KAT11 PF08214.11 EKX33123.1 - 0.032 13.5 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 Histone acetylation protein Acetyltransf_1 PF00583.25 EKX33124.1 - 2.4e-12 47.1 0.3 2.7e-12 47.0 0.3 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EKX33124.1 - 1.4e-10 41.5 0.1 1.7e-10 41.2 0.1 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EKX33124.1 - 1.6e-09 37.8 0.1 1.8e-09 37.6 0.1 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EKX33124.1 - 9.3e-09 35.1 0.1 1.1e-08 34.9 0.1 1.0 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EKX33124.1 - 0.00053 20.7 0.0 0.00058 20.5 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EKX33124.1 - 0.0015 18.6 0.1 0.0031 17.6 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 EKX33124.1 - 0.0041 16.8 0.0 0.0041 16.8 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 EKX33124.1 - 0.0074 16.4 0.1 0.01 15.9 0.1 1.3 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 EKX33124.1 - 0.01 16.0 0.0 0.011 15.9 0.0 1.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EKX33124.1 - 0.033 13.9 0.0 0.035 13.8 0.0 1.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Mito_carr PF00153.27 EKX33125.1 - 1.3e-07 31.5 5.7 0.018 14.9 0.2 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Kinesin PF00225.23 EKX33126.1 - 1e-51 175.9 1.0 4e-50 170.6 1.0 2.0 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX33126.1 - 6.4e-21 74.9 0.0 4.6e-20 72.1 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding zf_C2H2_10 PF18414.1 EKX33127.1 - 3.7 7.2 8.9 2.4 7.8 2.4 3.0 2 0 0 2 2 2 0 C2H2 type zinc-finger FKBP_C PF00254.28 EKX33128.1 - 4.8e-23 81.3 0.0 6e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase MORN PF02493.20 EKX33129.1 - 1.7e-11 43.3 15.9 2e-06 27.4 0.2 4.2 3 0 0 3 3 3 3 MORN repeat FAM176 PF14851.6 EKX33129.1 - 0.17 11.6 0.1 0.31 10.7 0.1 1.4 1 0 0 1 1 1 0 FAM176 family ubiquitin PF00240.23 EKX33130.1 - 2.6e-67 222.5 5.4 5.1e-33 112.7 0.5 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 EKX33130.1 - 5.6e-33 112.6 6.6 5.7e-16 58.1 0.7 2.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EKX33130.1 - 4.7e-11 43.0 1.8 0.00064 20.1 0.1 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 EKX33130.1 - 3.3e-08 33.3 0.2 0.0091 15.9 0.1 2.2 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EKX33130.1 - 1.4e-07 31.8 0.3 0.02 15.2 0.1 2.1 1 1 1 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EKX33130.1 - 2.9e-07 30.6 0.3 0.042 14.0 0.1 2.8 2 2 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EKX33130.1 - 2.8e-06 27.8 0.1 0.1 13.1 0.0 2.2 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EKX33130.1 - 0.00091 19.1 0.1 1.3 8.9 0.0 2.1 1 1 1 2 2 2 2 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 EKX33130.1 - 0.0013 18.7 8.1 14 5.8 0.0 4.0 4 0 0 4 4 4 0 Ubiquitin-like domain ACT_5 PF13710.6 EKX33130.1 - 0.003 17.4 0.6 2.7 7.9 0.0 2.3 2 0 0 2 2 2 2 ACT domain RelB PF04221.12 EKX33130.1 - 0.0033 17.4 0.0 3.3 7.7 0.0 2.2 2 0 0 2 2 2 2 RelB antitoxin UN_NPL4 PF11543.8 EKX33130.1 - 0.024 15.1 0.1 9.7 6.8 0.0 2.3 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 YcgR_2 PF12945.7 EKX33130.1 - 0.032 14.4 0.3 11 6.2 0.0 2.3 2 0 0 2 2 2 0 Flagellar protein YcgR DUF3861 PF12977.7 EKX33130.1 - 0.033 14.4 0.1 9.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 EKX33130.1 - 0.038 14.4 0.0 18 5.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) DUF969 PF06149.12 EKX33130.1 - 0.11 11.9 0.0 4.7 6.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF969) DUF3333 PF11812.8 EKX33130.1 - 0.13 12.5 0.9 17 5.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) Raf1_HTH PF18579.1 EKX33130.1 - 0.16 11.7 0.0 26 4.6 0.0 2.3 2 0 0 2 2 2 0 Rubisco accumulation factor 1 helix turn helix domain Tash_PEST PF07708.11 EKX33130.1 - 0.19 11.9 9.6 2.7 8.2 1.5 2.3 2 0 0 2 2 2 0 Tash protein PEST motif Plexin_cytopl PF08337.12 EKX33130.1 - 1 7.9 5.2 17 3.9 0.3 3.0 2 1 0 2 2 2 0 Plexin cytoplasmic RasGAP domain Acyl-CoA_dh_1 PF00441.24 EKX33131.1 - 1.9e-40 138.5 0.8 3.4e-40 137.7 0.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EKX33131.1 - 1.1e-32 113.0 0.1 4e-32 111.2 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EKX33131.1 - 2.3e-18 66.2 0.1 5.6e-18 64.9 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EKX33131.1 - 8.2e-17 61.7 0.1 1.6e-16 60.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Orn_Arg_deC_N PF02784.16 EKX33132.1 - 5.1e-76 255.3 0.0 6.2e-76 255.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EKX33132.1 - 1.7e-10 41.0 0.0 3e-10 40.2 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 EKX33132.1 - 0.00018 21.0 0.0 0.0003 20.3 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Glyoxalase PF00903.25 EKX33133.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily COG5 PF10392.9 EKX33134.1 - 4e-19 69.1 0.3 4e-19 69.1 0.3 3.6 4 0 0 4 4 4 1 Golgi transport complex subunit 5 Vps51 PF08700.11 EKX33134.1 - 9e-06 25.7 0.0 5.2e-05 23.2 0.0 2.5 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 EKX33134.1 - 1.2e-05 25.5 0.3 1.2e-05 25.5 0.3 4.2 5 1 0 5 5 5 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 EKX33134.1 - 0.44 10.6 3.8 0.66 10.0 0.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) hnRNP_Q_AcD PF18360.1 EKX33136.1 - 3.4e-25 87.8 3.3 1e-20 73.4 0.0 2.8 3 0 0 3 3 3 2 Heterogeneous nuclear ribonucleoprotein Q acidic domain zf-C3HC4_3 PF13920.6 EKX33137.1 - 1.2e-08 34.6 5.6 1.8e-08 34.1 5.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX33137.1 - 8.5e-08 32.0 7.8 1.3e-07 31.4 7.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX33137.1 - 1.1e-07 32.1 10.0 1.6e-07 31.5 10.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EKX33137.1 - 2.9e-06 27.1 6.2 4.9e-06 26.4 6.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EKX33137.1 - 2.9e-06 27.2 5.2 2.9e-06 27.2 5.2 2.3 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EKX33137.1 - 3.1e-06 27.3 8.4 5.1e-06 26.6 8.4 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EKX33137.1 - 4.4e-06 26.4 9.4 6.8e-06 25.8 9.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX33137.1 - 2.8e-05 23.9 7.4 4.6e-05 23.2 7.4 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EKX33137.1 - 0.0022 18.2 7.6 0.0044 17.3 7.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EKX33137.1 - 0.0035 17.3 3.0 0.0057 16.7 3.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 EKX33137.1 - 0.012 15.7 3.9 0.02 15.0 3.9 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 Beta_helix PF13229.6 EKX33138.1 - 1.1e-46 158.6 4.7 1.7e-13 50.7 0.0 4.6 1 1 3 4 4 4 4 Right handed beta helix region NosD PF05048.13 EKX33138.1 - 4e-26 91.8 0.0 2.3e-06 27.1 0.1 4.5 1 1 2 4 4 4 4 Periplasmic copper-binding protein (NosD) Ank_2 PF12796.7 EKX33138.1 - 3.1e-17 62.9 0.0 2.1e-10 41.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX33138.1 - 2.5e-14 53.1 0.0 7.2e-09 35.7 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX33138.1 - 2.9e-13 48.7 0.0 0.00054 20.2 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EKX33138.1 - 5.1e-13 49.3 0.4 2.1e-09 37.7 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX33138.1 - 5.9e-12 45.5 0.1 0.001 19.4 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat BTB_2 PF02214.22 EKX33138.1 - 1.8e-05 25.0 0.0 3.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EKX33138.1 - 0.03 14.6 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain Ion_trans PF00520.31 EKX33140.1 - 6.6e-74 248.2 83.8 4.2e-28 98.2 10.2 4.1 4 0 0 4 4 4 4 Ion transport protein DUF2634 PF10934.8 EKX33141.1 - 0.16 12.1 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2634) Methyltransf_11 PF08241.12 EKX33143.1 - 2.7e-19 69.6 0.2 4.3e-19 69.0 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX33143.1 - 8.9e-19 67.9 0.0 1.1e-18 67.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX33143.1 - 1.3e-17 64.0 0.0 1.6e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX33143.1 - 4.4e-17 62.6 0.3 6.4e-17 62.1 0.3 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX33143.1 - 3.9e-15 56.4 0.2 6.1e-15 55.8 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EKX33143.1 - 3e-09 36.7 0.3 3.9e-09 36.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 EKX33143.1 - 1.3e-07 31.2 0.0 1.6e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 EKX33143.1 - 1.7e-07 31.1 0.1 2.3e-07 30.6 0.1 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 EKX33143.1 - 3.4e-06 26.7 0.1 4.7e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EKX33143.1 - 5e-06 26.0 0.1 5.9e-06 25.8 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 EKX33143.1 - 6.8e-06 26.2 0.1 8.9e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EKX33143.1 - 0.00017 20.6 0.1 0.00022 20.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.9 EKX33143.1 - 0.00036 20.3 0.6 0.00075 19.3 0.6 1.4 1 1 0 1 1 1 1 Lysine methyltransferase AdoMet_MTase PF07757.13 EKX33143.1 - 0.0018 18.6 0.0 0.0034 17.7 0.0 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_15 PF09445.10 EKX33143.1 - 0.0036 16.9 0.1 0.006 16.2 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MetW PF07021.12 EKX33143.1 - 0.0072 15.9 0.5 0.011 15.3 0.5 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW DREV PF05219.12 EKX33143.1 - 0.02 14.0 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_18 PF12847.7 EKX33143.1 - 0.086 12.8 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase domain RP1-2 PF12042.8 EKX33143.1 - 0.12 12.3 0.7 0.19 11.6 0.7 1.2 1 0 0 1 1 1 0 Tubuliform egg casing silk strands structural domain TPMT PF05724.11 EKX33143.1 - 0.13 11.9 0.6 0.48 10.0 0.1 1.8 1 1 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) ABC_tran PF00005.27 EKX33144.1 - 2.6e-45 154.3 4.3 7e-27 94.6 0.0 3.6 3 2 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 EKX33144.1 - 2e-17 63.9 2.0 4.5e-07 30.0 0.2 4.4 2 2 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 EKX33144.1 - 5e-13 48.9 8.3 5e-13 48.9 8.3 3.4 3 0 0 3 3 3 1 ABC transporter SMC_N PF02463.19 EKX33144.1 - 6.6e-07 29.0 2.9 0.28 10.6 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EKX33144.1 - 9.9e-07 29.1 0.0 0.0072 16.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EKX33144.1 - 4.1e-06 26.8 0.1 0.1 12.7 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EKX33144.1 - 6.4e-06 25.8 0.1 0.071 12.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 EKX33144.1 - 1.7e-05 25.0 0.1 0.2 11.7 0.0 3.2 3 1 0 3 3 3 2 Dynamin family AAA_23 PF13476.6 EKX33144.1 - 4.8e-05 24.0 19.5 0.0018 18.9 0.0 3.7 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EKX33144.1 - 5.3e-05 23.2 0.1 0.24 11.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase ATP-synt_ab PF00006.25 EKX33144.1 - 8e-05 22.4 0.1 0.15 11.7 0.0 3.4 4 0 0 4 4 3 1 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 EKX33144.1 - 0.00017 20.9 0.0 0.38 9.9 0.1 2.8 2 1 0 2 2 2 2 NB-ARC domain AAA_14 PF13173.6 EKX33144.1 - 0.0033 17.5 0.3 0.43 10.6 0.2 3.4 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EKX33144.1 - 0.0033 17.7 0.0 0.81 9.9 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 EKX33144.1 - 0.0046 17.5 1.1 5.3 7.6 0.2 3.0 2 2 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EKX33144.1 - 0.006 17.0 6.5 0.18 12.2 0.0 3.7 2 1 1 3 3 3 1 AAA ATPase domain AAA PF00004.29 EKX33144.1 - 0.0078 16.6 5.8 0.027 14.9 0.0 3.7 3 2 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 EKX33144.1 - 0.0092 16.1 4.9 2.9 7.9 0.0 4.1 4 0 0 4 4 4 1 Helicase HerA, central domain Roc PF08477.13 EKX33144.1 - 0.0096 16.1 0.2 5.4 7.3 0.0 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 EKX33144.1 - 0.012 15.6 0.6 2 8.3 0.1 2.6 2 0 0 2 2 2 0 NACHT domain CKS PF01111.19 EKX33144.1 - 0.012 15.8 0.0 0.64 10.3 0.0 2.6 2 0 0 2 2 2 0 Cyclin-dependent kinase regulatory subunit RNA_helicase PF00910.22 EKX33144.1 - 0.018 15.4 2.5 2.3 8.6 0.0 3.3 4 0 0 4 4 3 0 RNA helicase FeoB_N PF02421.18 EKX33144.1 - 0.02 14.4 0.1 4.9 6.7 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.9 EKX33144.1 - 0.022 14.5 0.2 8.4 6.1 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 EKX33144.1 - 0.025 14.5 0.2 0.32 10.9 0.1 2.7 3 1 0 3 3 2 0 Rad17 P-loop domain SbcCD_C PF13558.6 EKX33144.1 - 0.048 13.9 0.3 17 5.7 0.0 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Adeno_IVa2 PF02456.15 EKX33144.1 - 0.05 12.4 0.4 1.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein PRK PF00485.18 EKX33144.1 - 0.058 13.1 0.1 12 5.6 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 EKX33144.1 - 0.064 13.4 2.8 1.9 8.6 0.0 3.1 4 0 0 4 4 2 0 AAA domain ATPase_2 PF01637.18 EKX33144.1 - 0.073 13.0 2.9 0.58 10.0 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea DLIC PF05783.11 EKX33144.1 - 0.12 11.2 3.1 3.2 6.5 0.0 2.7 3 0 0 3 3 2 0 Dynein light intermediate chain (DLIC) MeaB PF03308.16 EKX33144.1 - 0.13 11.3 4.4 1.3 8.0 0.0 2.8 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ALIX_LYPXL_bnd PF13949.6 EKX33144.1 - 0.14 11.4 11.1 0.37 10.1 0.3 2.2 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV AAA_24 PF13479.6 EKX33144.1 - 0.17 11.6 4.8 4.7 6.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain Ploopntkinase1 PF18748.1 EKX33144.1 - 0.18 11.3 0.0 6 6.3 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 AAA_27 PF13514.6 EKX33144.1 - 0.31 10.6 6.8 4.8 6.7 0.0 3.4 3 1 0 3 3 3 0 AAA domain AAA_13 PF13166.6 EKX33144.1 - 0.35 9.4 12.4 2.1 6.9 0.1 4.0 3 1 1 4 4 4 0 AAA domain ATP_bind_1 PF03029.17 EKX33144.1 - 0.4 10.4 1.1 43 3.8 0.0 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_15 PF13175.6 EKX33144.1 - 0.41 10.3 8.0 0.99 9.0 0.0 3.4 3 1 1 4 4 4 0 AAA ATPase domain DUF4407 PF14362.6 EKX33144.1 - 0.81 9.0 4.3 0.25 10.6 1.1 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4407) FeoB_Cyto PF17910.1 EKX33144.1 - 0.87 10.2 6.5 0.53 10.9 0.4 3.1 3 0 0 3 3 3 0 FeoB cytosolic helical domain Zeta_toxin PF06414.12 EKX33144.1 - 1.5 8.0 4.7 5.8 6.1 0.1 3.0 3 0 0 3 3 3 0 Zeta toxin LsmAD PF06741.13 EKX33144.1 - 2.3 8.8 7.2 1.4 9.5 1.0 2.8 2 1 1 3 3 3 0 LsmAD domain SRPRB PF09439.10 EKX33144.1 - 2.9 7.3 4.7 34 3.8 1.9 2.9 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit DUF1664 PF07889.12 EKX33144.1 - 3.8 7.6 5.3 28 4.7 0.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) CCDC-167 PF15188.6 EKX33144.1 - 5.7 7.3 11.0 0.14 12.5 1.6 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 RCC1 PF00415.18 EKX33145.1 - 1.4e-67 224.1 6.5 2.5e-11 44.0 0.1 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX33145.1 - 7.9e-23 79.7 36.8 1.7e-06 27.6 0.1 7.8 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat PH PF00169.29 EKX33146.1 - 5.6e-30 104.0 7.8 6.6e-16 58.7 0.3 2.8 3 0 0 3 3 3 2 PH domain PH_8 PF15409.6 EKX33146.1 - 1.8e-05 24.9 1.1 0.046 14.0 0.3 2.6 2 0 0 2 2 2 2 Pleckstrin homology domain PH_16 PF17838.1 EKX33146.1 - 0.00029 20.7 0.1 1.2 9.0 0.0 2.6 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 EKX33146.1 - 0.00036 20.9 16.7 0.13 12.7 4.8 4.4 2 2 0 2 2 2 2 Pleckstrin homology domain TPR_17 PF13431.6 EKX33146.1 - 0.00088 19.5 0.9 0.49 10.9 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX33146.1 - 0.02 15.2 5.5 0.76 10.1 3.4 2.6 1 1 2 3 3 3 0 Tetratricopeptide repeat PH_13 PF16652.5 EKX33146.1 - 0.036 13.9 0.2 2.8 7.7 0.1 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain TPR_8 PF13181.6 EKX33146.1 - 0.056 13.7 0.1 46 4.6 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EKX33146.1 - 0.11 12.6 2.2 19 5.7 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC5 PF12862.7 EKX33146.1 - 0.13 12.3 3.4 0.55 10.3 2.2 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 PP2C PF00481.21 EKX33147.1 - 7.1e-61 206.1 0.0 8e-61 205.9 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EKX33147.1 - 0.0025 17.8 0.1 0.031 14.2 0.1 2.2 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) CAV_VP3 PF04771.12 EKX33149.1 - 0.086 13.0 0.1 0.1 12.7 0.1 1.3 1 1 0 1 1 1 0 Chicken anaemia virus VP-3 protein Y_phosphatase PF00102.27 EKX33150.1 - 0.002 17.7 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 EKX33150.1 - 0.0034 17.1 0.0 0.0042 16.8 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 EKX33150.1 - 0.0093 16.1 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 EKX33150.1 - 0.014 15.2 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain MoaE PF02391.17 EKX33150.1 - 0.02 15.1 0.0 0.027 14.7 0.0 1.2 1 0 0 1 1 1 0 MoaE protein Y_phosphatase3 PF13350.6 EKX33150.1 - 0.082 12.9 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Tyrosine phosphatase family cNMP_binding PF00027.29 EKX33151.1 - 1.2e-08 34.9 0.0 1.7e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Pkinase PF00069.25 EKX33152.1 - 2e-12 47.0 0.0 3.7e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EKX33152.1 - 3.7e-06 26.4 0.0 0.0021 17.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX33152.1 - 0.058 12.2 0.0 0.076 11.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EKX33152.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RCC1_2 PF13540.6 EKX33153.1 - 1.4e-44 149.1 42.9 1.5e-09 37.4 1.1 6.1 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EKX33153.1 - 0.00065 20.3 41.1 0.15 12.7 0.2 9.9 10 2 1 11 11 11 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX33154.1 - 4.2e-36 122.0 51.4 2.6e-10 39.8 0.1 7.1 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EKX33154.1 - 0.00019 22.0 36.0 0.2 12.3 0.0 9.0 9 1 1 10 10 10 5 Regulator of chromosome condensation (RCC1) repeat VSP PF03302.13 EKX33154.1 - 0.00059 18.8 1.6 0.0011 18.0 1.3 1.7 1 1 0 1 1 1 1 Giardia variant-specific surface protein PLDc PF00614.22 EKX33154.1 - 0.079 13.2 0.2 6.4 7.1 0.1 3.2 3 0 0 3 3 3 0 Phospholipase D Active site motif MORN PF02493.20 EKX33155.1 - 3.6e-24 83.2 49.4 0.00019 21.1 0.0 7.5 7 0 0 7 7 7 6 MORN repeat DUF2201_N PF13203.6 EKX33155.1 - 3.2 7.3 6.7 0.32 10.6 2.0 1.6 2 0 0 2 2 2 0 Putative metallopeptidase domain Orn_Arg_deC_N PF02784.16 EKX33156.1 - 9.7e-40 136.5 0.0 2e-39 135.4 0.0 1.5 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EKX33156.1 - 1.7e-10 41.0 0.0 2.7e-10 40.3 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain HORMA PF02301.18 EKX33157.1 - 2e-24 86.4 0.8 2e-24 86.4 0.8 2.1 2 2 0 2 2 2 1 HORMA domain BofC_C PF08955.10 EKX33157.1 - 0.038 14.0 0.0 0.099 12.7 0.0 1.6 1 0 0 1 1 1 0 BofC C-terminal domain EF-hand_1 PF00036.32 EKX33159.1 - 1.4e-12 46.2 0.3 3.2e-06 26.3 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 EKX33159.1 - 3.2e-11 42.2 0.1 2.1e-05 23.8 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX33159.1 - 3e-09 37.2 0.0 5.7e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX33159.1 - 5.1e-09 35.4 0.0 0.0032 17.3 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EKX33159.1 - 8.1e-08 32.0 0.7 2.5e-06 27.2 0.1 2.9 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX33159.1 - 0.0037 17.6 0.0 0.0055 17.0 0.0 1.4 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 EKX33159.1 - 0.11 12.7 0.4 0.34 11.1 0.4 2.0 1 1 0 1 1 1 0 Dockerin type I domain PilP PF04351.13 EKX33159.1 - 0.13 12.2 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Pilus assembly protein, PilP DUF179 PF02622.15 EKX33160.1 - 5.6e-21 75.2 0.0 1.1e-20 74.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 Zn_clus PF00172.18 EKX33163.1 - 2.8e-14 52.9 51.8 3.1e-05 24.0 10.8 3.4 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 EKX33164.1 - 1.7e-15 56.9 53.1 3.1e-05 24.0 10.8 3.4 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain Retrotrans_gag PF03732.17 EKX33165.1 - 0.00024 21.3 0.9 0.0099 16.1 0.0 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein bZIP_1 PF00170.21 EKX33165.1 - 3.1 7.9 6.7 9.3 6.4 0.2 2.5 2 0 0 2 2 2 0 bZIP transcription factor Zn_clus PF00172.18 EKX33166.1 - 7.9e-13 48.3 50.7 0.0001 22.3 11.2 4.1 4 0 0 4 4 4 3 Fungal Zn(2)-Cys(6) binuclear cluster domain PK PF00224.21 EKX33167.1 - 1.1e-148 494.8 1.1 1.5e-148 494.3 1.1 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EKX33167.1 - 5e-24 84.8 0.3 1.3e-23 83.5 0.3 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EKX33167.1 - 4.1e-06 26.1 0.2 1.6e-05 24.2 0.2 2.0 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family NodZ PF05830.11 EKX33168.1 - 2.7e-05 23.2 0.0 4.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein Z (NodZ) O-FucT PF10250.9 EKX33168.1 - 4e-05 23.5 0.1 0.0001 22.2 0.1 1.6 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase EGF_2 PF07974.13 EKX33168.1 - 0.73 10.3 12.3 1.5 9.2 12.3 1.6 1 0 0 1 1 1 0 EGF-like domain TCR PF03638.15 EKX33168.1 - 5.9 7.3 7.6 11 6.4 7.6 1.4 1 0 0 1 1 1 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain EGF_Tenascin PF18720.1 EKX33168.1 - 8 6.6 9.1 19 5.5 9.1 1.6 1 0 0 1 1 1 0 Tenascin EGF domain MFS_1_like PF12832.7 EKX33169.1 - 2.2e-35 122.3 19.1 2.4e-35 122.1 19.1 1.0 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 EKX33169.1 - 8.9e-07 28.2 33.1 1.6e-06 27.3 32.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Nuc_H_symport PF03825.16 EKX33169.1 - 1.1e-06 27.9 14.2 1.3e-06 27.7 14.2 1.0 1 0 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 EKX33169.1 - 1.2e-05 24.2 11.5 1.3e-05 24.1 11.5 1.0 1 0 0 1 1 1 1 LacY proton/sugar symporter Shisa PF13908.6 EKX33170.1 - 0.00099 19.4 0.9 0.0024 18.1 0.9 1.6 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF2207 PF09972.9 EKX33170.1 - 0.017 13.9 1.8 0.02 13.6 1.0 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DAG1 PF05454.11 EKX33170.1 - 0.07 12.5 3.5 0.11 11.8 3.5 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) TMEM154 PF15102.6 EKX33170.1 - 0.41 10.5 6.8 0.84 9.5 6.8 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF4191 PF13829.6 EKX33170.1 - 0.45 9.8 3.6 0.72 9.1 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Orf78 PF06024.12 EKX33170.1 - 2.9 8.2 9.7 8.1 6.8 9.7 1.7 1 1 0 1 1 1 0 Orf78 (ac78) Misat_Tub_SegII PF10644.9 EKX33171.1 - 8.1e-15 55.2 2.3 1e-09 38.7 1.0 3.1 2 1 1 3 3 3 2 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EKX33171.1 - 7.2e-12 45.4 0.1 1.8e-11 44.0 0.1 1.7 1 0 0 1 1 1 1 Tubulin domain Zn_clus PF00172.18 EKX33171.1 - 4.9e-07 29.8 7.4 1.4e-06 28.3 7.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tubulin PF00091.25 EKX33171.1 - 1.7e-05 25.1 0.0 0.013 15.7 0.0 2.6 2 1 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Fea1 PF07692.11 EKX33172.1 - 1e-11 44.5 7.2 2.9e-11 43.0 7.2 1.8 1 1 0 1 1 1 1 Low iron-inducible periplasmic protein PKD_channel PF08016.12 EKX33173.1 - 7.4e-23 80.9 20.5 1.5e-17 63.5 11.1 2.4 2 0 0 2 2 2 2 Polycystin cation channel C2 PF00168.30 EKX33173.1 - 1.7e-20 73.2 0.1 3.9e-20 72.1 0.1 1.6 1 0 0 1 1 1 1 C2 domain CUB PF00431.20 EKX33173.1 - 2.7e-16 59.9 0.6 7.4e-16 58.5 0.2 2.0 2 0 0 2 2 2 1 CUB domain Ion_trans PF00520.31 EKX33173.1 - 1.2e-10 41.1 17.6 4.4e-10 39.2 17.6 1.9 1 1 0 1 1 1 1 Ion transport protein EF-hand_5 PF13202.6 EKX33173.1 - 0.024 14.1 0.2 0.069 12.7 0.2 1.8 1 0 0 1 1 1 0 EF hand DUF2098 PF09871.9 EKX33173.1 - 2 8.8 5.5 7.1 7.0 5.5 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) Paf1 PF03985.13 EKX33173.1 - 2.5 7.0 13.6 4.3 6.2 13.6 1.3 1 0 0 1 1 1 0 Paf1 FAM176 PF14851.6 EKX33173.1 - 5.9 6.6 7.3 17 5.0 7.3 1.8 1 0 0 1 1 1 0 FAM176 family TTL PF03133.15 EKX33174.1 - 1.3e-50 172.2 0.0 2.3e-50 171.4 0.0 1.3 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 EKX33174.1 - 2.9e-08 33.3 0.0 0.00047 19.5 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 EKX33174.1 - 1.3e-05 24.6 0.0 0.0038 16.5 0.0 2.6 3 1 0 3 3 3 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 EKX33174.1 - 0.00023 21.3 0.0 0.81 9.7 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 EKX33174.1 - 0.0014 18.2 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GSH-S_ATP PF02955.16 EKX33174.1 - 0.02 14.3 0.0 0.046 13.1 0.0 1.6 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, ATP-grasp domain DUF724 PF05266.14 EKX33174.1 - 0.04 13.7 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Dala_Dala_lig_C PF07478.13 EKX33174.1 - 0.15 11.5 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus EF-hand_7 PF13499.6 EKX33175.1 - 2.4e-12 47.1 0.7 2.7e-12 47.0 0.7 1.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX33175.1 - 2.6e-12 45.6 0.3 2.5e-06 27.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EKX33175.1 - 4.2e-12 44.7 1.8 5.4e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EKX33175.1 - 9.7e-11 40.7 2.6 0.00012 21.4 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX33175.1 - 3.3e-08 33.2 1.1 3.3e-05 23.6 0.2 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 EKX33175.1 - 0.00096 19.4 0.1 0.0011 19.3 0.1 1.0 1 0 0 1 1 1 1 EF-hand domain Toprim_2 PF13155.6 EKX33175.1 - 0.061 13.8 0.1 0.067 13.6 0.1 1.2 1 0 0 1 1 1 0 Toprim-like EF-hand_4 PF12763.7 EKX33175.1 - 0.11 12.5 0.6 0.15 12.0 0.6 1.3 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand PKD_channel PF08016.12 EKX33176.1 - 0.00064 18.5 5.5 0.00064 18.5 5.5 2.3 1 1 0 2 2 2 1 Polycystin cation channel V_ATPase_I PF01496.19 EKX33176.1 - 0.31 8.9 2.5 0.62 7.9 2.5 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cyt-b5 PF00173.28 EKX33177.1 - 7e-15 54.9 0.1 4.8e-14 52.3 0.1 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Globin PF00042.22 EKX33177.1 - 5e-13 49.6 0.0 0.00072 20.1 0.0 5.3 4 2 0 4 4 4 3 Globin DRIM PF07539.12 EKX33178.1 - 3.1e-39 134.8 25.4 2e-26 92.5 6.5 5.5 4 1 1 5 5 5 3 Down-regulated in metastasis HEAT PF02985.22 EKX33178.1 - 0.00078 19.5 4.9 24 5.5 0.0 6.4 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 EKX33178.1 - 0.0008 19.7 12.3 0.27 11.7 0.4 6.0 5 0 0 5 5 5 2 HEAT repeats Arm PF00514.23 EKX33178.1 - 0.0032 17.4 4.0 6.6 6.9 0.0 5.8 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EKX33178.1 - 0.23 12.0 13.4 20 5.8 0.7 7.9 9 0 0 9 9 9 0 HEAT-like repeat Collagen PF01391.18 EKX33181.1 - 2.4e-09 36.8 17.3 2.8e-09 36.6 17.3 1.0 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) PA14 PF07691.12 EKX33182.1 - 2.7e-39 134.3 5.8 5.8e-08 32.7 0.1 5.3 5 0 0 5 5 5 5 PA14 domain Collagen PF01391.18 EKX33182.1 - 2.8e-13 49.4 54.5 2.4e-08 33.6 23.0 2.8 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) SRCR PF00530.18 EKX33182.1 - 5.3e-07 30.1 5.4 4.3e-06 27.1 5.4 2.3 1 1 0 1 1 1 1 Scavenger receptor cysteine-rich domain GLEYA PF10528.9 EKX33182.1 - 4.6e-06 27.0 8.3 2.3 8.7 0.1 5.4 5 0 0 5 5 5 3 GLEYA domain Crystall_3 PF08964.10 EKX33182.1 - 0.015 15.5 0.0 0.041 14.1 0.0 1.8 1 0 0 1 1 1 0 Beta/Gamma crystallin DUF4034 PF13226.6 EKX33182.1 - 0.21 10.9 0.0 5.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4034) TPR_12 PF13424.6 EKX33183.1 - 0.017 15.4 16.2 0.2 12.0 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Pox_A_type_inc PF04508.12 EKX33183.1 - 0.037 13.9 0.1 0.16 11.9 0.1 2.2 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat EF-G-binding_N PF07299.11 EKX33183.1 - 0.14 12.7 0.1 0.49 10.9 0.1 1.9 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal TPR_2 PF07719.17 EKX33183.1 - 2.2 8.6 13.7 9.3 6.6 0.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX33183.1 - 3 8.3 6.6 24 5.5 0.2 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Mito_carr PF00153.27 EKX33184.1 - 1.5e-48 162.6 2.2 1.5e-15 56.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NHR2 PF08788.11 EKX33185.1 - 0.087 12.6 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 NHR2 domain like RRF PF01765.19 EKX33186.1 - 2.8e-47 160.7 7.6 2.8e-47 160.7 7.6 1.7 1 1 1 2 2 2 1 Ribosome recycling factor FmrO PF07091.11 EKX33186.1 - 0.057 13.0 0.0 0.069 12.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) DUF3512 PF12024.8 EKX33186.1 - 0.16 11.4 4.0 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3512) ubiquitin PF00240.23 EKX33187.1 - 8.4e-10 38.3 0.0 1.9e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 EKX33187.1 - 8.8e-05 22.6 0.1 0.00037 20.6 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EKX33187.1 - 0.00038 21.0 0.0 0.00087 19.8 0.0 1.7 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 EKX33187.1 - 0.0014 18.4 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 EKX33187.1 - 0.025 15.2 0.0 0.044 14.5 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_5 PF18037.1 EKX33187.1 - 0.064 13.6 0.1 0.13 12.7 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain PA14 PF07691.12 EKX33188.1 - 2.2e-06 27.5 0.0 6.2e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 PA14 domain MIB_HERC2 PF06701.13 EKX33189.1 - 5.6e-06 26.5 0.0 1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Mib_herc2 Sec63 PF02889.16 EKX33190.1 - 1.3e-08 34.3 0.0 2.3e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Sec63 Brl domain Pkinase PF00069.25 EKX33191.1 - 2.9e-59 200.6 0.1 3.5e-59 200.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX33191.1 - 3.6e-42 144.5 0.0 4.4e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX33191.1 - 1.1e-05 24.4 0.0 2.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EKX33191.1 - 0.0012 18.2 0.0 0.002 17.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like MCU PF04678.13 EKX33192.1 - 2.4e-35 122.2 0.6 4.8e-35 121.2 0.6 1.5 1 0 0 1 1 1 1 Mitochondrial calcium uniporter cNMP_binding PF00027.29 EKX33192.1 - 1.3e-11 44.4 0.3 1.1e-10 41.4 0.3 2.4 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain COR PF16095.5 EKX33192.1 - 6.7e-09 35.8 0.1 1.4e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain AAA_lid_9 PF17871.1 EKX33192.1 - 0.14 12.1 0.8 0.32 10.9 0.8 1.6 1 0 0 1 1 1 0 AAA lid domain ANAPC4_WD40 PF12894.7 EKX33193.1 - 9.4e-51 170.1 10.7 5.9e-11 42.5 0.2 10.2 1 1 9 10 10 10 9 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EKX33193.1 - 1.7e-49 164.7 30.0 1.6e-05 25.5 0.1 11.1 11 0 0 11 11 11 10 WD domain, G-beta repeat eIF2A PF08662.11 EKX33193.1 - 9e-14 51.8 0.1 0.008 16.1 0.0 6.2 1 1 4 7 7 7 5 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EKX33193.1 - 1.5e-12 47.1 0.1 0.054 12.4 0.0 6.7 1 1 4 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EKX33193.1 - 1.3e-10 40.9 3.8 2.6 8.1 0.0 9.3 10 0 0 10 10 10 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 EKX33193.1 - 4.5e-08 32.2 4.6 1.2 7.7 0.0 5.5 3 1 3 6 6 6 4 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EKX33193.1 - 1.7e-06 27.3 8.0 0.016 14.1 0.1 4.4 3 1 1 5 5 5 2 Partner and localizer of BRCA2 WD40 domain Nbas_N PF15492.6 EKX33193.1 - 4.5e-06 26.2 2.2 0.2 11.0 0.0 6.7 3 3 5 8 8 8 1 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 EKX33193.1 - 4.9e-05 22.3 0.0 7.1 5.2 0.0 6.0 2 2 6 8 8 8 1 Nup133 N terminal like Frtz PF11768.8 EKX33193.1 - 0.00013 20.5 0.0 0.013 13.9 0.0 3.4 4 0 0 4 4 4 1 WD repeat-containing and planar cell polarity effector protein Fritz ELYS-bb PF16687.5 EKX33193.1 - 0.00017 20.4 0.0 2.3 6.7 0.0 4.6 4 1 2 6 6 6 2 beta-propeller of ELYS nucleoporin Hira PF07569.11 EKX33193.1 - 0.00017 21.4 5.9 1.2 8.8 0.0 6.7 1 1 6 8 8 8 1 TUP1-like enhancer of split IKI3 PF04762.12 EKX33193.1 - 0.0065 14.5 10.0 0.97 7.3 0.3 4.4 1 1 3 5 5 5 3 IKI3 family CNH PF00780.22 EKX33193.1 - 0.033 13.8 0.0 51 3.3 0.0 3.3 3 0 0 3 3 3 0 CNH domain CDtoxinA PF03498.14 EKX33193.1 - 0.043 13.4 0.8 50 3.5 0.1 5.0 5 2 0 6 6 6 0 Cytolethal distending toxin A/C domain DUF1995 PF09353.10 EKX33196.1 - 2.7e-19 70.0 0.2 4.2e-19 69.4 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) WW PF00397.26 EKX33196.1 - 1.5e-14 53.8 2.4 1.5e-14 53.8 2.4 1.8 2 0 0 2 2 2 1 WW domain Glyco_hyd_101C PF17451.2 EKX33196.1 - 0.01 16.1 0.1 0.019 15.2 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain F420_ligase PF01996.16 EKX33197.1 - 0.0065 15.9 0.1 0.01 15.2 0.1 1.2 1 0 0 1 1 1 1 F420-0:Gamma-glutamyl ligase PH PF00169.29 EKX33198.1 - 9.2e-17 61.5 0.0 1.6e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 PH domain Pkinase PF00069.25 EKX33198.1 - 5.9e-09 35.7 0.1 7.9e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain PH_8 PF15409.6 EKX33198.1 - 1.9e-05 24.8 0.0 3.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 EKX33198.1 - 2.5e-05 24.3 0.0 5.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 PH domain Pkinase_Tyr PF07714.17 EKX33198.1 - 0.0003 20.2 0.0 0.00044 19.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Mito_carr PF00153.27 EKX33199.1 - 2.3e-61 203.7 1.7 1.6e-22 79.2 0.4 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ABC2_membrane PF01061.24 EKX33201.1 - 5.4e-54 182.8 53.4 6.9e-29 100.8 25.0 3.0 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 EKX33201.1 - 5.9e-39 133.7 0.0 7e-21 75.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EKX33201.1 - 3.5e-08 33.6 0.0 0.0003 20.7 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EKX33201.1 - 2.9e-07 31.0 0.1 0.0052 17.2 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EKX33201.1 - 1e-06 28.3 1.5 0.0031 17.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain PDR_assoc PF08370.11 EKX33201.1 - 1.7e-05 24.5 0.0 1.7e-05 24.5 0.0 3.4 3 0 0 3 3 2 1 Plant PDR ABC transporter associated SMC_N PF02463.19 EKX33201.1 - 1.9e-05 24.2 0.0 0.4 10.1 0.1 3.7 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EKX33201.1 - 2.6e-05 24.2 0.8 0.00037 20.4 0.3 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EKX33201.1 - 0.00033 20.9 0.1 1.4 9.2 0.1 2.7 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.7 EKX33201.1 - 0.00076 18.7 17.7 0.00076 18.7 17.7 3.7 4 0 0 4 4 4 1 ABC-2 family transporter protein AAA_30 PF13604.6 EKX33201.1 - 0.0008 19.2 0.5 0.29 10.8 1.1 2.6 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EKX33201.1 - 0.0011 19.4 0.1 4.6 7.7 0.1 3.2 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EKX33201.1 - 0.0028 17.3 0.5 0.12 11.9 0.1 2.6 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EKX33201.1 - 0.016 15.6 0.0 3.4 8.1 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 EKX33201.1 - 0.017 15.6 0.2 0.12 12.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EKX33201.1 - 0.041 13.9 0.3 6.6 6.8 0.1 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 EKX33201.1 - 0.042 14.0 0.1 3 8.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 EKX33201.1 - 0.056 13.2 1.5 12 5.5 0.4 2.9 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 EKX33201.1 - 0.073 13.6 0.0 6.9 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EKX33201.1 - 0.084 12.8 0.2 9.5 6.1 0.4 2.4 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 EKX33201.1 - 0.091 12.8 0.9 0.26 11.3 0.5 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 EKX33201.1 - 0.25 11.7 0.6 26 5.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain Cyclin_N PF00134.23 EKX33202.1 - 2e-09 37.3 0.1 4.4e-07 29.7 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 EKX33202.1 - 0.016 15.3 0.0 0.084 13.0 0.0 2.2 1 1 0 1 1 1 0 Cyclin, C-terminal domain HCNGP PF07818.13 EKX33204.1 - 0.011 16.4 0.0 0.013 16.2 0.0 1.2 1 0 0 1 1 1 0 HCNGP-like protein DUF4996 PF16387.5 EKX33204.1 - 0.11 13.0 0.0 2.4 8.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function Pkinase PF00069.25 EKX33205.1 - 2e-09 37.2 0.0 3.5e-09 36.4 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Ephrin_rec_like PF07699.13 EKX33207.1 - 3e-35 119.7 60.8 2.5e-12 46.3 6.9 6.1 4 2 2 6 6 6 6 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX33207.1 - 0.02 15.3 53.7 0.046 14.1 3.3 7.9 3 2 6 9 9 9 0 TNFR/NGFR cysteine-rich region Laminin_EGF PF00053.24 EKX33207.1 - 5 7.3 48.5 12 6.2 1.8 6.8 1 1 4 6 6 6 0 Laminin EGF domain FYVE PF01363.21 EKX33208.1 - 0.003 17.6 1.7 1.4 9.1 0.0 3.6 2 1 0 2 2 2 1 FYVE zinc finger TRAPP PF04051.16 EKX33208.1 - 0.011 15.5 0.2 0.021 14.5 0.2 1.4 1 0 0 1 1 1 0 Transport protein particle (TRAPP) component zf-RING_9 PF13901.6 EKX33208.1 - 0.012 15.6 1.1 0.076 13.0 0.0 2.2 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon DUF5071 PF16804.5 EKX33208.1 - 0.018 15.3 0.7 0.12 12.7 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5071) zf-BED PF02892.15 EKX33208.1 - 1.1 9.4 3.3 1.7 8.8 0.1 2.9 3 0 0 3 3 3 0 BED zinc finger Zn_Tnp_IS1595 PF12760.7 EKX33208.1 - 4.7 7.3 5.8 27 4.8 1.1 3.1 3 0 0 3 3 3 0 Transposase zinc-ribbon domain HSP70 PF00012.20 EKX33209.1 - 1.2e-22 79.9 13.7 4.1e-14 51.7 13.3 2.8 2 1 0 2 2 2 2 Hsp70 protein FPP PF05911.11 EKX33209.1 - 2.7e-05 22.6 16.3 4.3e-05 21.9 16.3 1.2 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil FtsA PF14450.6 EKX33209.1 - 0.012 16.1 0.6 6.7 7.2 0.0 3.5 3 0 0 3 3 3 0 Cell division protein FtsA CCD48 PF15799.5 EKX33209.1 - 0.024 13.0 13.6 0.049 11.9 13.6 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 ABC_trans_N PF14510.6 EKX33209.1 - 0.2 12.3 1.7 1.9 9.2 1.3 2.7 2 0 0 2 2 2 0 ABC-transporter N-terminal Exonuc_VII_L PF02601.15 EKX33209.1 - 0.47 10.0 10.7 1 8.9 10.7 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 EKX33209.1 - 0.81 7.5 9.7 0.46 8.3 7.2 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.6 EKX33209.1 - 3.2 8.2 7.5 6.6 7.2 7.5 1.6 1 0 0 1 1 1 0 AAA domain LMBR1 PF04791.16 EKX33209.1 - 4.4 6.1 7.0 6.4 5.6 7.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein ATG16 PF08614.11 EKX33209.1 - 6.1 7.0 24.0 26 5.0 24.0 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Ins145_P3_rec PF08709.11 EKX33210.1 - 1.3e-12 47.4 0.1 4.3e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RIH_assoc PF08454.11 EKX33210.1 - 4e-08 33.0 3.8 4e-08 33.0 3.8 4.4 5 0 0 5 5 5 1 RyR and IP3R Homology associated RYDR_ITPR PF01365.21 EKX33210.1 - 4.4e-06 26.3 6.9 4.4e-06 26.3 6.9 4.0 5 0 0 5 5 5 1 RIH domain Ctr PF04145.15 EKX33210.1 - 0.02 15.5 1.6 8 7.1 0.1 4.0 3 0 0 3 3 3 0 Ctr copper transporter family DUF725 PF05267.12 EKX33211.1 - 0.42 10.6 6.8 4.3 7.4 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF725) RabGAP-TBC PF00566.18 EKX33213.1 - 7.5e-05 22.5 0.3 0.00014 21.6 0.3 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain S6PP PF05116.13 EKX33214.1 - 5.4e-29 101.5 0.0 1.9e-19 70.2 0.0 2.2 1 1 1 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 EKX33214.1 - 1.3e-05 25.1 0.1 0.019 14.7 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase A2L_zn_ribbon PF08792.10 EKX33215.1 - 0.14 11.9 0.4 1.3 8.8 0.1 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain Cupin_3 PF05899.12 EKX33216.1 - 4.3e-05 23.1 0.0 7.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) PDZ PF00595.24 EKX33219.1 - 3.9e-06 27.1 1.3 5.6e-06 26.6 1.3 1.4 1 1 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX33219.1 - 0.00021 21.6 0.0 0.00027 21.2 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX33219.1 - 0.0015 18.4 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 PDZ domain DUF3506 PF12014.8 EKX33220.1 - 0.011 15.8 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) Laminin_G_3 PF13385.6 EKX33222.1 - 1.6e-13 51.0 0.1 2e-12 47.5 0.0 3.0 3 0 0 3 3 2 1 Concanavalin A-like lectin/glucanases superfamily TIG PF01833.24 EKX33222.1 - 0.00021 21.3 8.7 0.055 13.6 0.3 4.4 3 0 0 3 3 3 2 IPT/TIG domain EPTP PF03736.17 EKX33222.1 - 0.044 13.8 2.1 22 5.2 0.1 4.2 3 0 0 3 3 3 0 EPTP domain SAPS PF04499.15 EKX33222.1 - 0.073 11.8 0.3 0.11 11.2 0.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Tim54 PF11711.8 EKX33222.1 - 0.43 9.3 0.9 0.67 8.7 0.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF5122 PF17164.4 EKX33222.1 - 0.72 10.2 6.1 11 6.4 0.6 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller Nop14 PF04147.12 EKX33222.1 - 0.76 7.9 24.9 1.2 7.2 24.9 1.2 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 EKX33222.1 - 0.94 9.3 16.1 1.7 8.5 16.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Vfa1 PF08432.10 EKX33222.1 - 2.6 8.3 6.9 4.4 7.6 6.9 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Mpp10 PF04006.12 EKX33222.1 - 4.2 5.7 20.4 6.2 5.1 20.4 1.1 1 0 0 1 1 1 0 Mpp10 protein BSP_II PF05432.11 EKX33222.1 - 5 6.7 21.8 8.5 6.0 21.8 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CDC45 PF02724.14 EKX33222.1 - 5.7 5.1 17.8 8.9 4.5 17.8 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 EKX33222.1 - 9 5.5 26.7 15 4.7 26.7 1.2 1 0 0 1 1 1 0 NOA36 protein Laminin_G_3 PF13385.6 EKX33223.1 - 4.4e-12 46.4 0.0 2.8e-11 43.8 0.0 2.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily TIG PF01833.24 EKX33223.1 - 8.2e-05 22.6 0.1 8.2e-05 22.6 0.1 3.9 5 0 0 5 5 5 1 IPT/TIG domain Anth_Ig PF05587.13 EKX33223.1 - 0.0069 16.7 0.2 0.047 14.0 0.0 2.6 2 0 0 2 2 1 1 Anthrax receptor extracellular domain CNH PF00780.22 EKX33223.1 - 0.011 15.4 0.2 0.65 9.5 0.1 2.4 2 0 0 2 2 2 0 CNH domain DUF3915 PF13054.6 EKX33223.1 - 0.027 14.5 1.4 0.077 13.0 1.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Myc_N PF01056.18 EKX33223.1 - 0.027 14.4 6.4 0.048 13.6 6.4 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Trypan_PARP PF05887.11 EKX33223.1 - 0.039 13.9 7.0 0.071 13.1 7.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CPSF100_C PF13299.6 EKX33223.1 - 0.37 11.0 5.3 0.88 9.7 5.3 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SDA1 PF05285.12 EKX33223.1 - 2.1 7.7 13.1 3.5 7.0 13.1 1.2 1 0 0 1 1 1 0 SDA1 EPTP PF03736.17 EKX33223.1 - 2.1 8.4 14.2 4.7 7.3 0.2 6.2 7 0 0 7 7 7 0 EPTP domain RAB3GAP2_C PF14656.6 EKX33223.1 - 2.2 6.4 5.7 3.4 5.8 5.7 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus SpoIIP PF07454.11 EKX33223.1 - 2.5 7.5 7.6 4.3 6.7 7.6 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CDC45 PF02724.14 EKX33223.1 - 4.7 5.4 8.2 7.8 4.7 8.2 1.2 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 EKX33223.1 - 8.2 6.1 10.0 18 4.9 10.0 1.5 1 0 0 1 1 1 0 FAM176 family EIIBC-GUT_N PF03612.14 EKX33223.1 - 9.2 6.0 7.0 17 5.1 7.0 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Pkinase PF00069.25 EKX33224.1 - 9.7e-43 146.4 0.0 1.1e-42 146.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX33224.1 - 3.3e-25 88.8 0.0 3.8e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX33224.1 - 6.1e-05 22.5 0.0 8.8e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EKX33224.1 - 8.2e-05 21.5 0.1 0.00071 18.5 0.1 1.9 1 1 1 2 2 2 1 Fungal protein kinase APH PF01636.23 EKX33224.1 - 0.00037 20.5 0.0 0.0053 16.7 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family RWP-RK PF02042.15 EKX33225.1 - 1.1e-06 28.5 0.1 1.9e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX33226.1 - 0.057 13.4 0.1 0.12 12.4 0.0 1.6 2 0 0 2 2 2 0 RWP-RK domain CALCOCO1 PF07888.11 EKX33228.1 - 0.022 13.7 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Sushi PF00084.20 EKX33229.1 - 7.2e-18 64.9 80.6 0.00054 20.5 2.1 17.2 16 2 2 18 18 18 10 Sushi repeat (SCR repeat) ZU5 PF00791.20 EKX33229.1 - 2e-06 28.0 0.0 1.1e-05 25.7 0.0 2.3 2 0 0 2 2 2 1 ZU5 domain RRM_1 PF00076.22 EKX33230.1 - 1.1e-26 92.4 0.3 3.6e-07 29.9 0.0 6.1 5 1 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EKX33230.1 - 2e-05 24.4 1.3 0.74 9.7 0.0 4.5 4 1 1 5 5 5 3 Occluded RNA-recognition motif DUF1866 PF08952.11 EKX33230.1 - 0.00089 19.1 0.0 0.13 12.1 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF1866) Nup35_RRM_2 PF14605.6 EKX33230.1 - 0.012 15.6 0.0 1.6 8.8 0.0 3.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EKX33230.1 - 0.084 12.9 0.1 5.7 7.0 0.0 3.4 3 1 1 4 4 4 0 RNA binding motif BLM_N PF16202.5 EKX33231.1 - 0.031 13.4 1.2 0.046 12.8 1.2 1.4 1 1 0 1 1 1 0 N-terminal region of Bloom syndrome protein Myb_DNA-binding PF00249.31 EKX33234.1 - 5.9e-32 109.6 2.0 1.1e-16 60.8 0.1 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX33234.1 - 8.3e-28 96.4 2.6 4.4e-17 62.1 0.2 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EKX33234.1 - 7.7e-09 35.3 0.4 9.1e-06 25.5 0.1 2.1 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 EKX33234.1 - 8.2e-06 25.8 0.1 0.14 12.2 0.0 2.8 2 1 1 3 3 3 2 SLIDE Myb_DNA-bind_2 PF08914.11 EKX33234.1 - 0.00015 21.9 2.1 0.008 16.3 0.3 2.8 1 1 1 2 2 2 2 Rap1 Myb domain SANT_DAMP1_like PF16282.5 EKX33234.1 - 0.0021 18.2 0.6 0.0081 16.3 0.1 2.0 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 EKX33234.1 - 0.0027 17.8 0.1 0.26 11.4 0.1 2.2 1 1 1 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain TPR_12 PF13424.6 EKX33236.1 - 1.9e-12 47.3 7.7 9.2e-07 29.1 2.5 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX33236.1 - 2e-09 37.0 10.4 0.00023 20.9 0.3 4.0 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX33236.1 - 6.1e-09 35.3 1.1 0.0035 17.1 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX33236.1 - 0.0002 20.8 1.9 0.037 13.4 0.4 2.1 1 1 1 2 2 2 2 MalT-like TPR region TPR_8 PF13181.6 EKX33236.1 - 0.0074 16.4 0.8 0.12 12.6 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX33236.1 - 0.0084 16.1 2.3 0.16 12.2 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX33236.1 - 0.027 14.5 1.1 3.5 7.9 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF5113 PF17140.4 EKX33236.1 - 0.14 11.9 0.3 4.6 7.0 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5113) TPR_14 PF13428.6 EKX33236.1 - 4.2 8.4 8.8 19 6.4 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TRAM_LAG1_CLN8 PF03798.16 EKX33237.1 - 1.7e-07 31.2 11.5 2.5e-07 30.6 11.5 1.3 1 0 0 1 1 1 1 TLC domain RNA_pol_Rpb2_6 PF00562.28 EKX33238.1 - 1.5e-109 366.6 0.3 4.2e-109 365.2 0.3 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EKX33238.1 - 1.3e-35 122.7 0.0 4.6e-35 121.0 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 EKX33238.1 - 4.9e-28 97.1 0.0 9.6e-28 96.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 EKX33238.1 - 1.4e-16 60.2 0.0 2.9e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 EKX33238.1 - 3e-14 53.1 0.0 4.7e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EKX33238.1 - 1.4e-11 44.6 1.9 3.1e-08 33.9 1.9 2.8 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Ion_trans PF00520.31 EKX33239.1 - 7.5e-22 77.8 11.9 1.2e-21 77.0 11.9 1.2 1 0 0 1 1 1 1 Ion transport protein PH PF00169.29 EKX33239.1 - 0.00011 22.7 0.0 0.00027 21.4 0.0 1.8 1 0 0 1 1 1 1 PH domain PKD_channel PF08016.12 EKX33239.1 - 0.0026 16.5 12.6 0.045 12.4 0.9 2.9 1 1 2 3 3 3 2 Polycystin cation channel PH_9 PF15410.6 EKX33239.1 - 0.0084 16.5 0.1 0.031 14.6 0.1 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain EF-hand_8 PF13833.6 EKX33239.1 - 0.01 15.6 0.7 0.76 9.7 0.3 2.7 2 0 0 2 2 2 0 EF-hand domain pair Flavi_NS4A PF01350.17 EKX33239.1 - 0.25 11.3 2.3 0.7 9.8 1.3 2.2 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A Thioredoxin PF00085.20 EKX33241.1 - 0.00033 20.6 0.1 0.00098 19.1 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin HTH_WhiA PF02650.14 EKX33241.1 - 0.22 11.9 1.7 3.2 8.2 0.6 2.8 2 1 1 3 3 3 0 WhiA C-terminal HTH domain Sec23_trunk PF04811.15 EKX33242.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain Raptor_N PF14538.6 EKX33243.1 - 5.2e-67 224.4 0.0 1e-66 223.4 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 EKX33243.1 - 1.2e-08 34.4 0.1 0.00044 20.3 0.0 4.1 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 EKX33243.1 - 0.00035 21.0 0.5 0.025 15.1 0.1 3.2 3 1 0 3 3 3 1 HEAT-like repeat HEAT_2 PF13646.6 EKX33243.1 - 0.025 15.0 0.0 1.2 9.6 0.0 2.7 2 0 0 2 2 2 0 HEAT repeats RICTOR_V PF14668.6 EKX33243.1 - 0.1 12.9 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 Elf1 PF05129.13 EKX33244.1 - 0.075 13.1 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like SHE3 PF17078.5 EKX33245.1 - 0.00018 21.3 9.5 0.00018 21.3 9.5 3.4 2 1 2 4 4 4 2 SWI5-dependent HO expression protein 3 COMM_domain PF07258.14 EKX33245.1 - 0.58 10.3 5.2 0.3 11.2 1.4 2.6 2 0 0 2 2 2 0 COMM domain TLD PF07534.16 EKX33248.1 - 3.2e-15 56.6 0.0 6.6e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 TLD Vac_Fusion PF02346.16 EKX33248.1 - 3 7.5 7.9 2.5 7.8 0.6 3.8 4 0 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 zf-RanBP PF00641.18 EKX33249.1 - 9.1e-14 50.5 16.6 2e-09 36.6 5.2 2.2 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RecR PF02132.15 EKX33249.1 - 0.11 12.1 0.7 0.11 12.1 0.7 2.4 2 0 0 2 2 2 0 RecR protein DZR PF12773.7 EKX33249.1 - 0.17 11.9 7.5 1.1 9.4 7.7 2.0 1 1 1 2 2 2 0 Double zinc ribbon CTU2 PF10288.9 EKX33249.1 - 0.75 10.1 6.9 4.2 7.7 6.9 2.0 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-P11 PF03854.14 EKX33249.1 - 0.92 9.2 6.2 0.64 9.7 0.2 2.2 2 0 0 2 2 2 0 P-11 zinc finger DUF4250 PF14056.6 EKX33251.1 - 0.02 14.8 0.1 0.044 13.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) CT_C_D PF02682.16 EKX33251.1 - 0.16 11.7 0.3 8.5 6.0 0.1 2.3 1 1 1 2 2 2 0 Carboxyltransferase domain, subdomain C and D Y_phosphatase2 PF03162.13 EKX33252.1 - 6.6e-40 136.4 0.0 7.7e-40 136.2 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EKX33252.1 - 7e-05 22.7 0.0 8.6e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EKX33252.1 - 0.0061 16.5 0.0 0.0075 16.3 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EKX33252.1 - 0.025 14.1 0.1 0.029 13.9 0.1 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF4042 PF13251.6 EKX33252.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4042) BLOC1S3 PF15753.5 EKX33253.1 - 0.0026 17.9 2.0 0.0062 16.7 2.0 1.7 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex 1 subunit 3 TRPM_tetra PF16519.5 EKX33253.1 - 0.012 15.7 1.5 0.012 15.7 1.5 2.9 2 0 0 2 2 2 0 Tetramerisation domain of TRPM Exonuc_VII_L PF02601.15 EKX33253.1 - 0.027 14.0 14.3 6.7 6.2 14.3 2.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF713 PF05218.14 EKX33253.1 - 0.028 14.2 10.3 0.23 11.2 0.2 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF713) FlaC_arch PF05377.11 EKX33253.1 - 0.032 14.6 13.4 8 6.9 2.0 5.3 6 0 0 6 6 6 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 EKX33253.1 - 0.038 14.0 19.0 4.9 7.2 4.5 4.2 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) TSC22 PF01166.18 EKX33253.1 - 0.039 14.3 2.1 2.2 8.7 0.0 4.0 4 1 1 5 5 4 0 TSC-22/dip/bun family YqjK PF13997.6 EKX33253.1 - 0.2 11.9 1.1 11 6.4 0.0 3.3 2 0 0 2 2 2 0 YqjK-like protein Fib_alpha PF08702.10 EKX33253.1 - 0.34 11.1 13.8 1.8 8.7 5.6 3.6 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 EKX33253.1 - 0.98 9.9 9.7 34 5.0 0.3 4.5 2 1 3 5 5 5 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 EKX33253.1 - 1.1 9.3 7.7 26 4.8 4.6 3.5 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DNA_primase_lrg PF04104.14 EKX33253.1 - 1.8 7.9 4.5 2.6 7.4 3.6 1.7 1 1 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit DUF2730 PF10805.8 EKX33253.1 - 2.1 8.5 13.1 5.7 7.1 2.3 4.5 2 1 3 5 5 5 0 Protein of unknown function (DUF2730) Snapin_Pallidin PF14712.6 EKX33253.1 - 2.6 8.5 16.0 9.5 6.7 7.8 3.9 3 1 1 4 4 4 0 Snapin/Pallidin FAM76 PF16046.5 EKX33253.1 - 4.2 6.6 15.0 8.5 5.6 15.0 1.4 1 0 0 1 1 1 0 FAM76 protein DUF1319 PF07028.11 EKX33253.1 - 9.8 6.4 12.5 20 5.4 0.6 4.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1319) Methyltransf_16 PF10294.9 EKX33254.1 - 1.2e-33 116.2 0.0 2e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EKX33254.1 - 3.7e-05 23.6 0.0 5e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EKX33254.1 - 5.9e-05 22.7 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain GidB PF02527.15 EKX33254.1 - 0.0058 16.0 0.0 0.0095 15.3 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G PCMT PF01135.19 EKX33254.1 - 0.057 13.2 0.0 0.074 12.8 0.0 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.12 EKX33254.1 - 0.077 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase His_Phos_1 PF00300.22 EKX33256.1 - 3.2e-24 85.7 0.0 8.4e-24 84.3 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Oxidored_nitro PF00148.19 EKX33256.1 - 0.089 11.5 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase BHD_1 PF10403.9 EKX33256.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 1 LRR_4 PF12799.7 EKX33257.1 - 0.00024 21.4 0.3 0.4 11.2 0.1 3.2 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX33257.1 - 0.0045 17.3 1.0 8.2 7.4 0.0 3.7 4 0 0 4 4 4 1 Leucine Rich Repeat SAM_Ste50p PF09235.10 EKX33257.1 - 0.0073 16.5 0.7 1.7 8.9 1.2 3.0 2 1 1 3 3 3 1 Ste50p, sterile alpha motif LRR_6 PF13516.6 EKX33257.1 - 0.17 12.0 0.4 29 5.0 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich repeat KASH_CCD PF14662.6 EKX33258.1 - 0.00037 20.4 17.6 0.00037 20.4 17.6 3.2 1 1 2 3 3 3 1 Coiled-coil region of CCDC155 or KASH TPR_MLP1_2 PF07926.12 EKX33258.1 - 0.01 15.9 13.2 0.01 15.9 13.2 3.9 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein AKNA PF12443.8 EKX33258.1 - 0.033 14.8 11.7 0.043 14.5 2.0 2.9 2 1 0 2 2 2 0 AT-hook-containing transcription factor LBP_M PF17385.2 EKX33258.1 - 0.13 11.8 0.4 0.26 10.8 0.4 1.6 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase central domain zf-C4pol PF14260.6 EKX33258.1 - 0.14 12.7 7.6 0.3 11.6 0.9 3.1 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta DUF2935 PF11155.8 EKX33258.1 - 0.14 12.5 13.9 2.2 8.6 4.0 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) WD40_alt PF14077.6 EKX33258.1 - 0.16 11.9 3.0 0.77 9.7 0.4 3.0 2 0 0 2 2 2 0 Alternative WD40 repeat motif HAMP_N3 PF18575.1 EKX33258.1 - 0.17 11.5 0.4 2.5 7.8 0.0 2.7 3 0 0 3 3 3 0 HAMP N-terminal domain 3 TrbI_Ftype PF09677.10 EKX33258.1 - 0.19 12.1 2.5 0.5 10.7 0.6 2.6 2 0 0 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) Rootletin PF15035.6 EKX33258.1 - 0.21 11.6 36.2 0.21 11.6 17.4 3.5 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion KLRAQ PF10205.9 EKX33258.1 - 0.91 9.8 32.9 0.043 14.0 7.0 4.6 1 1 3 4 4 4 0 Predicted coiled-coil domain-containing protein GIT_CC PF16559.5 EKX33258.1 - 1.1 9.2 16.4 0.49 10.3 2.4 4.5 3 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4200 PF13863.6 EKX33258.1 - 1.7 9.1 41.2 19 5.7 9.8 4.5 2 2 1 3 3 3 0 Domain of unknown function (DUF4200) Tropomyosin PF00261.20 EKX33258.1 - 1.8 7.9 35.3 0.019 14.4 14.3 2.9 1 1 0 2 2 2 0 Tropomyosin Mto2_bdg PF12808.7 EKX33258.1 - 7.6 6.9 13.8 0.74 10.1 0.3 4.5 2 1 2 4 4 4 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Myb_DNA-binding PF00249.31 EKX33260.1 - 2.9e-10 40.2 0.3 4.7e-10 39.5 0.3 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX33260.1 - 9.4e-09 35.4 1.6 1.7e-08 34.6 1.6 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 EKX33260.1 - 0.24 11.5 4.7 0.52 10.4 4.7 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Amidohydro_1 PF01979.20 EKX33261.1 - 7e-10 38.7 0.0 9.9e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 EKX33261.1 - 0.033 14.0 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase CRAL_TRIO PF00650.20 EKX33263.1 - 2.2e-09 37.2 0.0 3.5e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CUE PF02845.16 EKX33263.1 - 0.0086 15.8 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 CUE domain DMA PF03474.14 EKX33263.1 - 0.053 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 DMRTA motif LRR_6 PF13516.6 EKX33264.1 - 5.9e-12 44.6 7.9 0.00041 20.2 0.1 5.6 5 0 0 5 5 5 4 Leucine Rich repeat LRR_1 PF00560.33 EKX33264.1 - 1.2 10.0 8.4 16 6.5 1.2 4.4 3 2 1 4 4 4 0 Leucine Rich Repeat WD40 PF00400.32 EKX33265.1 - 9.1e-07 29.5 0.0 0.00059 20.6 0.2 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX33265.1 - 3.1e-05 24.2 0.0 2.5 8.4 0.0 4.6 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2415 PF10313.9 EKX33265.1 - 0.0022 17.9 0.0 0.0054 16.6 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) Pkinase PF00069.25 EKX33270.1 - 0.00036 20.0 0.0 0.00036 20.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RT_RNaseH_2 PF17919.1 EKX33271.1 - 5.7e-36 122.6 0.1 1.3e-35 121.4 0.1 1.7 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 EKX33271.1 - 4.9e-33 113.5 0.1 1.5e-32 112.0 0.1 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 EKX33271.1 - 3.8e-19 68.6 0.0 9.2e-19 67.3 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 EKX33271.1 - 7.6e-19 68.1 0.1 9.9e-18 64.5 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.27 EKX33271.1 - 7.1e-14 51.8 0.3 6.8e-13 48.6 0.1 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve_3 PF13683.6 EKX33271.1 - 0.021 14.6 0.0 0.079 12.7 0.0 2.0 1 0 0 1 1 1 0 Integrase core domain RVT_3 PF13456.6 EKX33271.1 - 0.038 13.8 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 0 Reverse transcriptase-like mRNA_cap_enzyme PF01331.19 EKX33275.1 - 0.007 16.2 0.0 0.009 15.8 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.21 EKX33275.1 - 0.081 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 ATP dependent DNA ligase domain FecR PF04773.13 EKX33278.1 - 0.06 14.0 0.0 0.085 13.5 0.0 1.2 1 0 0 1 1 1 0 FecR protein CD52 PF15116.6 EKX33278.1 - 0.31 11.1 20.4 25 5.0 0.2 5.4 1 1 7 8 8 8 0 CAMPATH-1 antigen Collagen PF01391.18 EKX33279.1 - 0.0013 18.5 16.7 0.002 17.9 16.7 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) IL10 PF00726.17 EKX33280.1 - 0.07 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Interleukin 10 HTH_23 PF13384.6 EKX33282.1 - 0.00016 21.3 0.0 0.00026 20.7 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 EKX33282.1 - 0.004 16.9 0.3 0.026 14.3 0.3 2.2 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 EKX33282.1 - 0.0056 16.6 0.6 0.085 12.8 0.1 2.4 2 1 1 3 3 3 1 Helix-turn-helix domain HTH_3 PF01381.22 EKX33282.1 - 0.014 15.4 0.1 0.028 14.5 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix Sigma70_r4 PF04545.16 EKX33282.1 - 0.028 13.9 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_19 PF12844.7 EKX33282.1 - 0.096 12.7 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain CTF_NFI PF00859.18 EKX33282.1 - 0.12 12.3 1.8 0.14 12.1 1.8 1.1 1 0 0 1 1 1 0 CTF/NF-I family transcription modulation region SET PF00856.28 EKX33284.1 - 0.029 14.8 0.0 0.053 13.9 0.0 1.3 1 0 0 1 1 1 0 SET domain Band_7 PF01145.25 EKX33286.1 - 1.6e-28 100.0 2.0 2.3e-28 99.4 2.0 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 EKX33286.1 - 5e-06 25.8 1.5 6.2e-06 25.5 1.5 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial Med2 PF11214.8 EKX33286.1 - 0.012 15.8 2.1 0.028 14.6 2.1 1.6 1 0 0 1 1 1 0 Mediator complex subunit 2 DUF3498 PF12004.8 EKX33287.1 - 0.15 11.3 0.3 0.19 10.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) TPR_17 PF13431.6 EKX33288.1 - 0.0006 20.0 0.1 7.2 7.2 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX33288.1 - 0.0018 18.0 3.4 1.1 9.2 0.3 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX33288.1 - 0.012 15.4 2.0 0.6 10.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX33288.1 - 0.021 15.6 1.8 16 6.7 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX33288.1 - 0.053 13.8 4.0 0.14 12.4 0.5 3.0 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EKX33288.1 - 0.12 12.5 4.3 2.7 8.3 0.5 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX33288.1 - 1.1 9.6 3.5 12 6.4 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Arm_vescicular PF18770.1 EKX33289.1 - 0.00043 20.2 1.5 0.0092 15.9 0.2 2.6 3 0 0 3 3 3 2 Armadillo tether-repeat of vescicular transport factor EB PF01683.18 EKX33290.1 - 5.9 7.3 32.9 6.9 7.1 3.5 4.3 2 2 0 3 3 3 0 EB module Nup96 PF12110.8 EKX33291.1 - 0.032 13.3 0.1 0.047 12.8 0.1 1.2 1 0 0 1 1 1 0 Nuclear protein 96 DEAD PF00270.29 EKX33294.1 - 1.3e-46 158.5 0.1 2.4e-46 157.7 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX33294.1 - 3.3e-30 104.7 0.1 3.1e-28 98.3 0.1 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX33294.1 - 8.7e-07 29.1 0.1 5.1e-06 26.6 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EKX33294.1 - 0.059 13.7 0.8 0.67 10.2 0.1 2.6 2 2 0 2 2 2 0 AAA domain Pkinase PF00069.25 EKX33295.1 - 3.5e-41 141.3 0.0 4.7e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX33295.1 - 7.5e-38 130.3 0.0 1e-37 129.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX33295.1 - 0.16 11.3 0.0 0.4 10.0 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Thioredoxin PF00085.20 EKX33296.1 - 1.4e-29 102.1 0.1 1.6e-29 101.9 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EKX33296.1 - 1.7e-05 25.2 0.1 2.9e-05 24.5 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EKX33296.1 - 3.2e-05 24.2 0.0 0.002 18.4 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.6 EKX33296.1 - 0.00015 21.9 0.1 0.00021 21.4 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 EKX33296.1 - 0.016 14.6 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Rad9_Rad53_bind PF08605.10 EKX33296.1 - 0.09 13.0 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Fungal Rad9-like Rad53-binding TraF PF13728.6 EKX33296.1 - 0.14 11.9 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein DUF1966 PF09260.11 EKX33298.1 - 0.13 12.5 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1966) RabGAP-TBC PF00566.18 EKX33299.1 - 2.4e-45 154.8 0.5 2.9e-45 154.6 0.5 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ank_2 PF12796.7 EKX33300.1 - 3.3e-07 30.8 0.0 3.4e-06 27.5 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX33300.1 - 3.6e-07 30.3 0.0 2.2e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX33300.1 - 5.1e-07 29.9 0.0 0.00092 19.6 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EKX33300.1 - 6e-07 29.3 0.0 0.0037 17.6 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EKX33300.1 - 1.6e-05 25.3 0.0 0.00017 22.0 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) FAD_binding_3 PF01494.19 EKX33301.1 - 6.5e-30 104.6 0.0 7.3e-29 101.1 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EKX33301.1 - 1.4e-07 31.6 0.0 3.1e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EKX33301.1 - 1.6e-07 30.8 0.1 6.6e-07 28.7 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EKX33301.1 - 1.4e-06 27.3 0.0 2.5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 EKX33301.1 - 4.7e-06 26.0 0.1 9.6e-05 21.7 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 EKX33301.1 - 6.3e-06 26.0 0.2 5.4e-05 22.9 0.2 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EKX33301.1 - 7.3e-06 25.3 0.0 0.00035 19.7 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EKX33301.1 - 7.7e-06 25.4 0.3 4.8e-05 22.7 0.2 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EKX33301.1 - 4.5e-05 22.7 0.0 6.8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EKX33301.1 - 0.00074 18.9 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 EKX33301.1 - 0.0013 18.4 0.0 0.0058 16.2 0.0 2.1 2 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.6 EKX33301.1 - 0.0054 16.7 0.1 0.027 14.4 0.1 2.0 1 1 0 1 1 1 1 FAD-NAD(P)-binding 3HCDH_N PF02737.18 EKX33301.1 - 0.0057 16.6 0.0 0.0088 15.9 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 EKX33301.1 - 0.0095 15.3 1.2 0.015 14.7 1.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.16 EKX33301.1 - 0.023 14.3 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 EKX33301.1 - 0.05 14.2 0.1 0.26 11.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EKX33301.1 - 0.07 12.4 0.3 1.1 8.5 0.2 2.0 1 1 0 2 2 2 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 EKX33301.1 - 0.15 11.4 0.0 0.6 9.4 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Aminotran_1_2 PF00155.21 EKX33302.1 - 1.5e-56 192.1 0.0 1.9e-56 191.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EKX33302.1 - 4.4e-06 26.2 0.1 1.3e-05 24.7 0.1 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EKX33302.1 - 7.2e-06 25.2 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EKX33302.1 - 9.4e-06 24.4 0.0 1.4e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EKX33302.1 - 0.00041 19.8 0.1 0.0014 18.0 0.1 1.8 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.20 EKX33302.1 - 0.0066 15.2 0.1 0.013 14.2 0.1 1.4 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain DSPc PF00782.20 EKX33303.1 - 5.6e-07 29.5 0.0 7.7e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX33303.1 - 7.2e-07 29.0 0.0 8.6e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EKX33303.1 - 0.00022 21.3 0.0 0.00025 21.1 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EKX33303.1 - 0.0039 17.3 0.1 0.0062 16.7 0.1 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.12 EKX33303.1 - 0.11 12.2 0.2 0.16 11.6 0.2 1.4 1 1 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Rhodanese PF00581.20 EKX33303.1 - 0.18 12.3 0.2 2.8 8.5 0.2 2.1 1 1 0 1 1 1 0 Rhodanese-like domain UBX PF00789.20 EKX33304.1 - 1.3e-13 51.0 0.0 2.8e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 EKX33304.1 - 2e-11 43.5 0.4 4.8e-11 42.3 0.4 1.7 1 0 0 1 1 1 1 UBA-like domain Borrelia_P83 PF05262.11 EKX33304.1 - 0.037 12.5 3.5 0.042 12.3 3.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein UBA_5 PF16577.5 EKX33304.1 - 0.064 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 UBA domain Rep_4 PF05797.11 EKX33304.1 - 0.57 9.2 4.9 0.12 11.5 1.7 1.4 2 0 0 2 2 2 0 Yeast trans-acting factor (REP1/REP2) EPL1 PF10513.9 EKX33305.1 - 0.013 15.9 2.6 0.013 15.9 2.6 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like zf-Paramyx-P PF13008.7 EKX33305.1 - 0.15 11.5 1.4 0.31 10.5 1.4 1.4 1 0 0 1 1 1 0 Zinc-binding domain of Paramyxoviridae V protein BCDHK_Adom3 PF10436.9 EKX33305.1 - 0.2 11.5 6.5 0.03 14.2 2.2 1.7 2 0 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DIM PF08194.12 EKX33305.1 - 0.42 10.8 1.4 0.8 10.0 1.4 1.4 1 0 0 1 1 1 0 DIM protein RGS12_us1 PF16613.5 EKX33305.1 - 0.89 9.9 5.3 0.57 10.5 1.0 2.4 2 0 0 2 2 2 0 Unstructured region of RGS12 FANCI_S2 PF14676.6 EKX33305.1 - 1 9.7 5.2 0.17 12.2 0.6 1.9 2 0 0 2 2 2 0 FANCI solenoid 2 Macoilin PF09726.9 EKX33305.1 - 1 7.8 24.9 1.3 7.5 24.9 1.1 1 0 0 1 1 1 0 Macoilin family DUF3450 PF11932.8 EKX33305.1 - 2.2 7.5 24.3 2.1 7.6 8.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4775 PF16001.5 EKX33305.1 - 2.3 7.6 14.4 0.83 9.0 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4775) RWP-RK PF02042.15 EKX33306.1 - 1.7e-14 53.5 0.0 3.1e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain DUF3670 PF12419.8 EKX33306.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 SNF2 Helicase protein CK_II_beta PF01214.18 EKX33307.1 - 0.03 14.2 0.6 0.054 13.3 0.6 1.3 1 0 0 1 1 1 0 Casein kinase II regulatory subunit DUF1904 PF08921.11 EKX33308.1 - 0.044 14.1 0.0 0.084 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1904) zf-C4 PF00105.18 EKX33311.1 - 0.17 12.4 1.0 0.32 11.5 1.0 1.4 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) Ribosomal_L13 PF00572.18 EKX33312.1 - 6.4e-09 36.1 0.3 3.6e-07 30.5 0.0 2.6 2 1 0 2 2 2 1 Ribosomal protein L13 Glucosamine_iso PF01182.20 EKX33314.1 - 3e-38 132.0 0.0 3.6e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase LysM PF01476.20 EKX33316.1 - 0.13 12.4 0.0 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 LysM domain GTP_EFTU PF00009.27 EKX33317.1 - 9.8e-41 139.4 0.0 1.3e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EKX33317.1 - 6.2e-25 87.7 0.1 3.5e-24 85.3 0.0 2.3 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EKX33317.1 - 1.9e-06 28.1 0.0 4.9e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 EKX33317.1 - 5.7e-05 22.9 0.1 0.00017 21.4 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 EKX33317.1 - 0.00015 21.8 0.0 0.0024 17.9 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase TUDOR_5 PF18359.1 EKX33317.1 - 0.024 14.3 0.2 0.077 12.7 0.1 1.9 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain 1 HBS1_N PF08938.10 EKX33317.1 - 0.033 14.5 0.1 0.033 14.5 0.1 2.2 2 0 0 2 2 2 0 HBS1 N-terminus DUF1325 PF07039.11 EKX33317.1 - 0.062 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 SGF29 tudor-like domain DUF4537 PF15057.6 EKX33317.1 - 0.084 12.9 0.0 0.26 11.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) Collagen PF01391.18 EKX33318.1 - 0.24 11.2 5.5 0.54 10.1 5.5 1.7 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) Phosphorylase PF00343.20 EKX33321.1 - 1.7e-298 991.8 0.0 2.1e-298 991.6 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase Thioredoxin_6 PF13848.6 EKX33322.1 - 3.3e-05 23.9 0.0 8.2e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain UPF0004 PF00919.20 EKX33322.1 - 0.17 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein family UPF0004 GRDP-like PF07173.12 EKX33323.1 - 0.018 15.7 0.8 0.018 15.7 0.8 2.3 2 0 0 2 2 2 0 Glycine-rich domain-containing protein-like Sec34 PF04136.15 EKX33323.1 - 0.023 14.6 0.4 0.023 14.6 0.4 3.2 2 2 2 4 4 4 0 Sec34-like family WXG100 PF06013.12 EKX33323.1 - 5.2 7.4 15.7 2.8 8.2 0.6 4.4 3 2 1 4 4 4 0 Proteins of 100 residues with WXG Guanylate_cyc PF00211.20 EKX33324.1 - 8.3e-43 146.1 0.0 9.2e-43 146.0 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Thiolase_N PF00108.23 EKX33325.1 - 8.5e-59 199.0 0.6 1.2e-58 198.6 0.6 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EKX33325.1 - 2e-42 143.7 2.9 2.1e-42 143.7 0.1 2.3 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EKX33325.1 - 0.0054 16.3 2.7 0.081 12.5 1.3 2.9 2 1 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain PARP PF00644.20 EKX33325.1 - 0.15 11.7 0.1 0.27 10.8 0.1 1.3 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain LRR_4 PF12799.7 EKX33327.1 - 8e-18 64.3 32.1 2.1e-06 28.0 0.8 4.3 1 1 6 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX33327.1 - 5.9e-17 61.2 23.9 1.8e-06 27.6 1.8 3.5 3 1 0 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 EKX33327.1 - 2.6e-08 33.6 4.4 0.0037 16.8 0.9 3.0 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 EKX33327.1 - 0.00083 19.2 16.9 13 6.1 0.3 5.6 5 0 0 5 5 5 4 Leucine Rich repeat RNase_PH PF01138.21 EKX33328.1 - 9.6e-23 81.1 0.8 2.2e-10 41.1 0.1 3.0 3 0 0 3 3 3 2 3' exoribonuclease family, domain 1 KH_1 PF00013.29 EKX33328.1 - 6.7e-08 32.3 1.4 7.1e-05 22.5 0.2 2.7 2 0 0 2 2 2 2 KH domain RNase_PH_C PF03725.15 EKX33328.1 - 8.6e-07 28.9 0.1 0.00053 20.0 0.0 3.2 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 TraO PF10626.9 EKX33328.1 - 0.072 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Conjugative transposon protein TraO NIR_SIR PF01077.22 EKX33329.1 - 2.5e-31 108.4 0.0 7.8e-17 61.2 0.0 2.1 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 EKX33329.1 - 9.2e-17 60.7 0.0 1.8e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain WD40 PF00400.32 EKX33330.1 - 8.5e-28 96.0 18.0 3.7e-05 24.4 0.1 10.8 10 1 1 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX33330.1 - 6.8e-18 64.8 0.2 0.00012 22.3 0.0 6.0 4 3 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EKX33330.1 - 0.00084 19.3 0.2 2.7 7.9 0.1 4.5 3 2 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EKX33330.1 - 0.039 12.6 0.1 15 4.1 0.0 3.0 3 0 0 3 3 3 0 Nucleoporin Nup120/160 FSH1 PF03959.13 EKX33331.1 - 1.2e-22 80.7 0.0 7.4e-22 78.1 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EKX33331.1 - 0.0032 18.1 0.0 0.0038 17.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Porin_3 PF01459.22 EKX33332.1 - 2.1e-45 155.3 1.4 2.4e-45 155.1 1.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin PDZ_6 PF17820.1 EKX33334.1 - 6.6e-13 48.3 0.1 1.2e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX33334.1 - 8.5e-12 45.2 0.1 2.2e-11 43.9 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX33334.1 - 2.9e-10 40.4 0.2 5.9e-10 39.4 0.2 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX33334.1 - 0.0038 17.2 0.1 0.0089 16.0 0.1 1.6 1 0 0 1 1 1 1 Tricorn protease PDZ domain COR PF16095.5 EKX33334.1 - 0.14 11.9 0.2 0.25 11.1 0.2 1.3 1 0 0 1 1 1 0 C-terminal of Roc, COR, domain Alba PF01918.21 EKX33335.1 - 0.0016 18.2 0.2 0.0024 17.6 0.2 1.3 1 0 0 1 1 1 1 Alba Keratin_2_head PF16208.5 EKX33335.1 - 0.017 15.2 18.7 0.024 14.8 18.7 1.3 1 0 0 1 1 1 0 Keratin type II head DUF5320 PF17253.2 EKX33335.1 - 0.029 15.4 9.6 0.039 15.0 9.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5320) Sporozoite_P67 PF05642.11 EKX33335.1 - 0.43 8.6 8.8 0.48 8.4 8.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3482 PF11981.8 EKX33335.1 - 0.45 9.8 13.2 0.54 9.6 13.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) KRTAP PF11759.8 EKX33335.1 - 1.5 9.4 19.5 2.6 8.6 19.5 1.4 1 0 0 1 1 1 0 Keratin-associated matrix Forkhead_N PF08430.12 EKX33335.1 - 3.4 8.3 6.3 0.84 10.3 2.4 1.7 2 0 0 2 2 2 0 Forkhead N-terminal region TraT PF05818.12 EKX33335.1 - 7 6.3 11.6 11 5.6 11.6 1.4 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein IKI3 PF04762.12 EKX33336.1 - 1.8e-131 440.0 0.0 1.3e-120 404.1 0.0 2.0 1 1 1 2 2 2 2 IKI3 family ANAPC4_WD40 PF12894.7 EKX33336.1 - 4.2e-07 30.2 0.0 0.025 14.9 0.0 5.2 6 1 0 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Robl_LC7 PF03259.17 EKX33336.1 - 0.013 15.2 0.3 0.26 11.1 0.0 3.2 4 0 0 4 4 4 0 Roadblock/LC7 domain mRNA_cap_enzyme PF01331.19 EKX33336.1 - 0.082 12.7 0.0 0.32 10.8 0.0 2.0 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain Minor_capsid_2 PF11114.8 EKX33336.1 - 0.11 12.6 0.0 1.6 8.8 0.0 2.2 2 0 0 2 2 2 0 Minor capsid protein WD40 PF00400.32 EKX33336.1 - 0.53 11.2 15.9 12 6.9 0.0 6.2 7 1 0 7 7 7 0 WD domain, G-beta repeat Peptidase_C97 PF05903.14 EKX33337.1 - 9e-23 80.8 0.0 9.7e-23 80.7 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 EKX33337.1 - 0.019 15.3 0.0 0.022 15.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin retinol acyltransferase DUF4064 PF13273.6 EKX33338.1 - 0.0094 16.2 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) SfLAP PF11139.8 EKX33338.1 - 0.025 14.0 0.1 0.049 13.1 0.1 1.4 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein DUF4834 PF16118.5 EKX33338.1 - 0.061 14.3 0.3 0.12 13.3 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) CoA_transf_3 PF02515.17 EKX33338.1 - 0.065 12.4 0.3 0.1 11.7 0.3 1.2 1 0 0 1 1 1 0 CoA-transferase family III DUF4381 PF14316.6 EKX33338.1 - 0.074 13.3 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) GRIM-19 PF06212.12 EKX33338.1 - 0.14 12.1 0.4 0.25 11.3 0.4 1.3 1 0 0 1 1 1 0 GRIM-19 protein DUF4446 PF14584.6 EKX33338.1 - 0.28 11.2 1.3 0.43 10.6 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Carb_anhydrase PF00194.21 EKX33339.1 - 2.6e-12 46.8 0.1 2.2e-11 43.8 0.1 2.3 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase TPX2_importin PF12214.8 EKX33339.1 - 0.04 14.1 1.5 0.082 13.1 1.5 1.5 1 1 0 1 1 1 0 Cell cycle regulated microtubule associated protein DDE_Tnp_1_7 PF13843.6 EKX33341.1 - 6e-17 62.0 0.0 6.3e-17 61.9 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.21 EKX33341.1 - 0.064 12.9 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain zf-C4 PF00105.18 EKX33342.1 - 0.045 14.2 1.0 0.11 13.0 1.0 1.6 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) Ephrin_rec_like PF07699.13 EKX33343.1 - 1.1e-56 188.3 137.3 2.7e-08 33.5 5.3 15.1 9 6 7 16 16 16 15 Putative ephrin-receptor like NCD3G PF07562.14 EKX33343.1 - 1.7e-09 37.5 108.2 0.0051 16.8 4.5 13.6 10 3 3 13 13 13 7 Nine Cysteines Domain of family 3 GPCR hEGF PF12661.7 EKX33343.1 - 0.00011 22.7 37.6 0.22 12.2 0.3 10.6 9 0 0 9 9 9 3 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 EKX33343.1 - 0.00055 19.9 32.3 0.98 9.5 0.2 9.4 8 0 0 8 8 8 4 MSP1 EGF domain 1 cEGF PF12662.7 EKX33343.1 - 0.012 15.6 0.5 0.012 15.6 0.5 11.9 13 2 1 14 14 14 0 Complement Clr-like EGF-like V_ATPase_I PF01496.19 EKX33344.1 - 0.00056 18.0 5.5 0.00057 18.0 5.5 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.20 EKX33344.1 - 0.0008 19.3 8.7 0.0008 19.3 8.7 2.3 2 0 0 2 2 2 1 Prefoldin subunit AAA_13 PF13166.6 EKX33344.1 - 0.0023 16.6 7.6 0.0023 16.6 7.6 2.0 1 1 1 2 2 2 1 AAA domain APG6_N PF17675.1 EKX33344.1 - 0.003 18.1 7.1 0.003 18.1 7.1 2.1 1 1 1 2 2 2 1 Apg6 coiled-coil region ADIP PF11559.8 EKX33344.1 - 0.0032 17.6 14.9 0.04 14.0 14.9 2.0 1 1 0 1 1 1 1 Afadin- and alpha -actinin-Binding SKA1 PF07160.12 EKX33344.1 - 0.0048 16.8 11.7 0.0062 16.4 11.7 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 Prefoldin_3 PF13758.6 EKX33344.1 - 0.0057 16.7 1.9 0.0057 16.7 1.9 2.7 1 1 1 3 3 3 1 Prefoldin subunit Spc7 PF08317.11 EKX33344.1 - 0.0097 14.8 18.3 0.012 14.5 18.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein T3SSipB PF16535.5 EKX33344.1 - 0.015 15.8 6.2 0.024 15.1 6.2 1.3 1 0 0 1 1 1 0 Type III cell invasion protein SipB DUF1664 PF07889.12 EKX33344.1 - 0.015 15.4 2.6 0.015 15.4 2.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Prefoldin PF02996.17 EKX33344.1 - 0.017 15.0 3.0 0.017 15.0 3.0 2.2 2 0 0 2 2 2 0 Prefoldin subunit Val_tRNA-synt_C PF10458.9 EKX33344.1 - 0.018 15.3 1.4 0.018 15.3 1.4 3.4 2 1 1 3 3 2 0 Valyl tRNA synthetase tRNA binding arm FlxA PF14282.6 EKX33344.1 - 0.02 14.9 16.2 1.1 9.3 14.1 2.2 1 1 1 2 2 2 0 FlxA-like protein XhlA PF10779.9 EKX33344.1 - 0.031 14.5 5.4 0.031 14.5 5.4 2.0 2 0 0 2 2 1 0 Haemolysin XhlA DUF812 PF05667.11 EKX33344.1 - 0.047 12.6 19.4 0.11 11.4 19.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Golgin_A5 PF09787.9 EKX33344.1 - 0.058 12.9 14.4 0.074 12.5 14.4 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Transcrip_act PF04949.13 EKX33344.1 - 0.087 12.7 23.9 2.1 8.2 23.1 2.1 1 1 0 1 1 1 0 Transcriptional activator DUF745 PF05335.13 EKX33344.1 - 0.13 11.9 8.2 0.19 11.4 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) CCDC53 PF10152.9 EKX33344.1 - 0.16 12.4 11.7 0.21 12.0 11.7 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex CC2-LZ PF16516.5 EKX33344.1 - 0.22 11.9 22.2 0.61 10.5 22.2 1.7 1 1 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Tektin PF03148.14 EKX33344.1 - 0.25 10.1 16.8 0.89 8.2 16.9 1.7 1 1 0 1 1 1 0 Tektin family ABC_tran_CTD PF16326.5 EKX33344.1 - 0.42 10.9 19.1 1.9e+03 -0.8 19.1 2.7 1 1 0 1 1 1 0 ABC transporter C-terminal domain DUF4407 PF14362.6 EKX33344.1 - 0.63 9.3 7.8 0.75 9.1 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2968 PF11180.8 EKX33344.1 - 0.66 9.6 11.3 1.1 8.8 11.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) GAS PF13851.6 EKX33344.1 - 0.91 8.8 22.2 0.028 13.7 2.9 1.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4140 PF13600.6 EKX33344.1 - 1.4 9.4 18.1 0.17 12.3 1.5 2.9 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) LMBR1 PF04791.16 EKX33344.1 - 1.4 7.7 4.5 1.5 7.6 4.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Noelin-1 PF12308.8 EKX33344.1 - 1.4 8.9 7.2 0.3 11.1 0.7 2.4 1 1 1 2 2 2 0 Neurogenesis glycoprotein Laminin_II PF06009.12 EKX33344.1 - 1.4 8.9 12.6 2.9 7.9 12.6 1.5 1 1 0 1 1 1 0 Laminin Domain II DegS PF05384.11 EKX33344.1 - 1.7 8.1 19.6 3.2 7.2 19.6 1.4 1 0 0 1 1 1 0 Sensor protein DegS Fib_alpha PF08702.10 EKX33344.1 - 1.8 8.8 13.0 0.044 14.0 4.5 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Snf7 PF03357.21 EKX33344.1 - 1.8 8.1 22.6 59 3.2 22.6 2.5 1 1 0 1 1 1 0 Snf7 BLOC1_2 PF10046.9 EKX33344.1 - 2.1 8.7 10.8 0.85 10.0 1.9 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 T3SS_needle_E PF08988.10 EKX33344.1 - 2.1 8.5 5.5 2.3 8.4 3.4 2.1 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle CCDC-167 PF15188.6 EKX33344.1 - 2.6 8.4 23.0 2.7 8.4 1.8 2.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Fmp27_WPPW PF10359.9 EKX33344.1 - 2.9 6.7 13.0 4.1 6.2 13.0 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TMPIT PF07851.13 EKX33344.1 - 2.9 7.1 15.8 4.2 6.5 15.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein Effector_1 PF04518.12 EKX33344.1 - 3.1 6.8 8.4 0.11 11.6 2.1 1.6 1 1 1 2 2 2 0 Effector from type III secretion system DUF4200 PF13863.6 EKX33344.1 - 3.3 8.1 27.5 5.7 7.4 7.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DivIC PF04977.15 EKX33344.1 - 4 7.3 22.0 0.24 11.2 3.6 2.3 2 0 0 2 2 2 0 Septum formation initiator Ax_dynein_light PF10211.9 EKX33344.1 - 4.2 7.3 23.7 0.3 11.0 4.5 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain Syntaxin-6_N PF09177.11 EKX33344.1 - 5.1 7.7 12.3 99 3.6 12.2 2.3 1 1 0 1 1 1 0 Syntaxin 6, N-terminal COG2 PF06148.11 EKX33344.1 - 6.1 6.9 10.7 21 5.2 10.2 2.0 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF5082 PF16888.5 EKX33344.1 - 7.1 6.9 17.6 0.11 12.8 3.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) YabA PF06156.13 EKX33344.1 - 8.5 7.1 13.8 62 4.3 13.8 2.0 1 1 0 1 1 1 0 Initiation control protein YabA DASH_Duo1 PF08651.10 EKX33344.1 - 9.4 6.1 10.9 1.3 8.9 0.8 3.0 3 1 1 4 4 3 0 DASH complex subunit Duo1 AAA PF00004.29 EKX33345.1 - 8e-43 146.0 0.0 2.2e-42 144.6 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EKX33345.1 - 2.7e-24 84.9 0.1 3.8e-23 81.3 0.1 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 EKX33345.1 - 1.4e-11 44.3 1.1 1.4e-11 44.3 1.1 2.9 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 EKX33345.1 - 1.9e-08 34.0 0.0 6.2e-08 32.3 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EKX33345.1 - 2.2e-06 28.2 1.0 0.001 19.5 0.1 3.2 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EKX33345.1 - 7.3e-06 26.3 0.7 0.0044 17.3 0.2 3.5 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 EKX33345.1 - 7.8e-06 25.2 0.0 1.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EKX33345.1 - 1.4e-05 24.9 0.0 2.9e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EKX33345.1 - 2e-05 24.6 0.0 8.4e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 EKX33345.1 - 2.5e-05 24.5 0.0 6.6e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EKX33345.1 - 5.5e-05 23.0 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 EKX33345.1 - 0.0002 21.3 0.0 0.00071 19.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EKX33345.1 - 0.00031 20.9 0.0 0.001 19.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EKX33345.1 - 0.0021 17.7 1.2 0.16 11.5 0.1 3.2 2 1 1 3 3 3 1 AAA domain RNA_helicase PF00910.22 EKX33345.1 - 0.0028 18.0 0.0 0.0063 16.9 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 EKX33345.1 - 0.0038 17.8 0.0 0.013 16.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 EKX33345.1 - 0.0081 15.4 2.2 1.4 8.1 0.1 3.1 2 1 1 3 3 3 1 KAP family P-loop domain AAA_24 PF13479.6 EKX33345.1 - 0.0088 15.8 0.3 0.029 14.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EKX33345.1 - 0.023 15.2 0.0 0.06 13.9 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.21 EKX33345.1 - 0.025 13.9 0.2 0.071 12.5 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 EKX33345.1 - 0.027 13.7 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain DUF4349 PF14257.6 EKX33345.1 - 0.027 13.9 0.0 0.18 11.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) AAA_7 PF12775.7 EKX33345.1 - 0.051 13.1 0.1 0.2 11.1 0.0 2.0 2 1 0 2 2 2 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 EKX33345.1 - 0.055 13.2 0.0 0.17 11.6 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase PF06745.13 EKX33345.1 - 0.06 12.7 0.5 8.2 5.7 0.0 2.4 1 1 1 2 2 2 0 KaiC TniB PF05621.11 EKX33345.1 - 0.068 12.6 0.0 12 5.2 0.0 2.5 1 1 0 2 2 2 0 Bacterial TniB protein Viral_helicase1 PF01443.18 EKX33345.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Cytidylate_kin PF02224.18 EKX33345.1 - 0.083 12.6 0.8 0.18 11.5 0.1 1.9 2 0 0 2 2 2 0 Cytidylate kinase DUF2791 PF10923.8 EKX33345.1 - 0.091 11.6 0.1 0.93 8.3 0.0 2.2 2 0 0 2 2 2 0 P-loop Domain of unknown function (DUF2791) SesA PF17107.5 EKX33345.1 - 0.12 12.6 0.3 0.32 11.2 0.3 1.7 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases PhoH PF02562.16 EKX33345.1 - 0.13 11.7 0.1 0.29 10.6 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_17 PF13207.6 EKX33345.1 - 0.13 12.7 3.3 0.24 11.8 0.0 2.8 2 2 1 3 3 3 0 AAA domain TPR_12 PF13424.6 EKX33345.1 - 0.13 12.5 0.1 0.42 10.9 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat ATPase_2 PF01637.18 EKX33345.1 - 0.2 11.5 1.0 4.7 7.1 0.0 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea TPR_1 PF00515.28 EKX33345.1 - 0.71 9.8 2.6 1.1 9.2 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat ADH_zinc_N PF00107.26 EKX33346.1 - 3.7e-08 33.4 0.0 6.5e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EKX33346.1 - 0.0049 16.7 0.1 0.099 12.5 0.1 2.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EKX33346.1 - 0.028 14.3 0.8 0.97 9.4 0.1 2.9 3 0 0 3 3 3 0 N-terminal domain of oxidoreductase Pet20 PF08692.10 EKX33346.1 - 0.053 14.2 0.0 0.13 13.0 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial protein Pet20 MBF1 PF08523.10 EKX33347.1 - 0.14 12.6 2.9 0.21 12.1 2.9 1.3 1 0 0 1 1 1 0 Multiprotein bridging factor 1 PepSY_2 PF13670.6 EKX33347.1 - 1.5 8.8 4.8 8.7 6.4 0.4 2.4 1 1 1 2 2 2 0 Peptidase propeptide and YPEB domain TK PF00265.18 EKX33348.1 - 1.6e-56 190.9 0.0 1.8e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 Thymidine kinase AAA_14 PF13173.6 EKX33348.1 - 0.0021 18.1 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain HNH_5 PF14279.6 EKX33348.1 - 0.027 14.3 0.1 0.057 13.3 0.1 1.5 1 0 0 1 1 1 0 HNH endonuclease Cytochrome_C7 PF14522.6 EKX33348.1 - 0.068 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c TLD PF07534.16 EKX33349.1 - 0.0015 18.8 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 TLD Pro_isomerase PF00160.21 EKX33350.1 - 9.9e-47 159.1 0.1 1.2e-46 158.9 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD LRR_8 PF13855.6 EKX33351.1 - 2.7e-81 267.2 164.1 2.6e-10 39.9 3.3 23.4 16 7 8 24 24 24 22 Leucine rich repeat LRR_4 PF12799.7 EKX33351.1 - 1e-71 235.6 163.3 1.7e-06 28.2 0.4 28.5 21 7 7 29 29 29 24 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX33351.1 - 5.1e-11 42.4 69.7 0.013 15.1 2.0 11.6 12 2 1 13 13 13 8 Leucine-rich repeat F5_F8_type_C PF00754.25 EKX33351.1 - 2.1e-08 34.4 0.0 4e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 F5/8 type C domain LRR_5 PF13306.6 EKX33351.1 - 2.1e-05 24.5 9.1 0.089 12.8 1.7 5.8 7 1 1 8 8 8 3 BspA type Leucine rich repeat region (6 copies) EF-hand_7 PF13499.6 EKX33351.1 - 0.29 11.6 0.9 4.7 7.7 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain pair PAZ PF02170.22 EKX33351.1 - 0.31 10.9 2.4 22 4.9 0.0 3.7 3 0 0 3 3 3 0 PAZ domain LRR_2 PF07723.13 EKX33351.1 - 0.54 11.0 16.6 5.7 7.8 0.0 8.1 9 0 0 9 9 9 0 Leucine Rich Repeat ThiF PF00899.21 EKX33352.1 - 3.7e-07 29.8 1.0 0.0014 18.0 0.0 2.7 2 1 1 3 3 3 2 ThiF family E1_4HB PF16191.5 EKX33352.1 - 0.01 16.0 0.1 0.067 13.4 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 four-helix bundle Pho86 PF11124.8 EKX33352.1 - 0.62 9.5 3.4 0.99 8.8 3.4 1.2 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 DUF4820 PF16091.5 EKX33353.1 - 0.37 10.1 9.1 0.41 10.0 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) MCM_bind PF09739.9 EKX33353.1 - 1.1 7.6 8.1 1.1 7.6 8.1 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor RPN2_C PF18004.1 EKX33353.1 - 1.2 9.1 13.6 1.4 8.8 13.6 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CDC45 PF02724.14 EKX33353.1 - 1.2 7.3 22.4 1.1 7.4 22.4 1.0 1 0 0 1 1 1 0 CDC45-like protein MRNIP PF15749.5 EKX33353.1 - 1.5 9.5 7.0 2.1 9.1 7.0 1.3 1 0 0 1 1 1 0 MRN-interacting protein Mpp10 PF04006.12 EKX33353.1 - 1.6 7.1 25.7 1.6 7.1 25.7 1.0 1 0 0 1 1 1 0 Mpp10 protein DNA_pol_phi PF04931.13 EKX33353.1 - 1.8 6.6 37.0 2 6.4 37.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi FYDLN_acid PF09538.10 EKX33353.1 - 1.9 9.2 24.4 2.5 8.8 24.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Nop14 PF04147.12 EKX33353.1 - 2.2 6.4 30.2 2.1 6.4 30.2 1.0 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.10 EKX33353.1 - 2.8 8.2 11.9 3.4 8.0 11.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RNA_pol_Rpc4 PF05132.14 EKX33353.1 - 3.5 8.1 9.0 3.7 8.0 9.0 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF2457 PF10446.9 EKX33353.1 - 4.2 6.4 37.0 4.3 6.4 37.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RR_TM4-6 PF06459.12 EKX33353.1 - 4.9 6.9 11.4 5.4 6.8 11.4 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 IFT57 PF10498.9 EKX33353.1 - 4.9 6.0 13.6 5.2 5.9 13.6 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 NPR3 PF03666.13 EKX33353.1 - 6.3 5.5 10.8 6.2 5.5 10.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TRAP_alpha PF03896.16 EKX33353.1 - 6.5 5.9 16.3 6.5 5.9 16.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit BUD22 PF09073.10 EKX33353.1 - 7 5.9 25.5 6.9 5.9 25.5 1.0 1 0 0 1 1 1 0 BUD22 Paf1 PF03985.13 EKX33353.1 - 7.1 5.5 23.2 7.5 5.4 23.2 1.0 1 0 0 1 1 1 0 Paf1 NARP1 PF12569.8 EKX33353.1 - 8.3 5.2 11.1 8.1 5.2 11.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SAP PF02037.27 EKX33354.1 - 3.6e-23 80.8 15.2 1.3e-06 28.0 0.1 5.4 5 0 0 5 5 5 4 SAP domain DnaJ PF00226.31 EKX33354.1 - 2.1e-07 31.0 0.0 8.1e-07 29.1 0.0 2.1 1 0 0 1 1 1 1 DnaJ domain Ish1 PF10281.9 EKX33354.1 - 1.6e-06 28.3 0.7 0.28 11.5 0.1 4.9 4 0 0 4 4 4 1 Putative stress-responsive nuclear envelope protein SAP30_Sin3_bdg PF13867.6 EKX33354.1 - 2.7e-06 27.6 0.0 0.036 14.4 0.0 3.3 3 0 0 3 3 3 2 Sin3 binding region of histone deacetylase complex subunit SAP30 Rho_N PF07498.12 EKX33354.1 - 0.0014 18.5 8.9 0.0063 16.4 0.0 5.0 6 0 0 6 6 6 1 Rho termination factor, N-terminal domain HeH PF12949.7 EKX33354.1 - 0.0089 15.7 0.6 0.18 11.6 0.1 3.3 3 0 0 3 3 3 1 HeH/LEM domain DTHCT PF08070.11 EKX33354.1 - 0.033 14.9 13.0 0.033 14.9 13.0 2.8 2 0 0 2 2 2 0 DTHCT (NUC029) region zf-ribbon_3 PF13248.6 EKX33354.1 - 0.048 13.1 0.1 0.19 11.2 0.1 2.0 1 0 0 1 1 1 0 zinc-ribbon domain LETM1 PF07766.13 EKX33354.1 - 0.14 11.5 0.1 0.14 11.5 0.1 3.3 3 1 0 3 3 3 0 LETM1-like protein Glycos_transf_2 PF00535.26 EKX33355.1 - 2.6e-22 79.4 0.0 1.5e-21 76.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 EKX33355.1 - 3.6e-08 33.2 0.0 1.6e-07 31.1 0.0 1.8 1 1 1 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 EKX33355.1 - 9.1e-08 32.3 0.0 1.5e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EKX33355.1 - 0.0014 19.1 0.0 0.0032 17.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF3322 PF11795.8 EKX33355.1 - 0.029 14.4 0.6 5 7.1 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Glyco_hydro_130 PF04041.13 EKX33357.1 - 3.9e-14 52.3 0.0 5e-09 35.5 0.0 2.1 2 0 0 2 2 2 2 beta-1,4-mannooligosaccharide phosphorylase Glyco_hydro_43 PF04616.14 EKX33357.1 - 0.001 18.5 0.0 0.0021 17.4 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 BNR_3 PF13859.6 EKX33357.1 - 0.062 12.6 0.0 0.062 12.6 0.0 1.9 2 1 0 2 2 2 0 BNR repeat-like domain GMC_oxred_N PF00732.19 EKX33358.1 - 1.1e-81 274.5 0.2 1.4e-81 274.1 0.2 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EKX33358.1 - 6.1e-35 120.8 0.0 9.6e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EKX33358.1 - 8.5e-05 22.7 0.2 0.00024 21.3 0.1 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EKX33358.1 - 0.00066 18.8 0.1 0.0011 18.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 EKX33358.1 - 0.0027 17.0 0.1 0.0043 16.3 0.1 1.2 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EKX33358.1 - 0.0032 17.1 0.0 0.0066 16.1 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EKX33358.1 - 0.015 14.4 0.1 0.026 13.6 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 EKX33358.1 - 0.017 13.9 0.0 0.034 12.8 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 EKX33358.1 - 0.039 13.3 0.1 0.068 12.5 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EKX33358.1 - 0.046 13.0 0.1 0.17 11.1 0.0 1.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EKX33358.1 - 0.053 12.4 0.3 0.088 11.6 0.1 1.4 2 0 0 2 2 2 0 Tryptophan halogenase Fip1 PF05182.13 EKX33358.1 - 0.13 11.8 1.2 0.79 9.3 0.3 2.3 2 0 0 2 2 2 0 Fip1 motif DUF3649 PF12365.8 EKX33359.1 - 0.14 11.9 0.5 0.14 11.9 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) Pkinase_Tyr PF07714.17 EKX33360.1 - 1.9e-63 214.2 0.0 2.2e-63 214.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX33360.1 - 1.9e-50 171.7 0.0 2.3e-50 171.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 EKX33360.1 - 5.6e-06 25.5 0.0 9.7e-06 24.7 0.0 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EKX33360.1 - 0.00067 18.6 0.0 0.00092 18.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX33360.1 - 0.0027 17.7 0.1 0.016 15.2 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family PH PF00169.29 EKX33361.1 - 0.026 15.0 0.0 0.048 14.2 0.0 1.3 1 0 0 1 1 1 0 PH domain Pyrophosphatase PF00719.19 EKX33362.1 - 9.5e-54 181.5 0.5 4e-43 147.0 0.0 2.9 3 0 0 3 3 3 2 Inorganic pyrophosphatase DUF1523 PF07509.11 EKX33362.1 - 0.015 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1523) GP67 PF17634.2 EKX33362.1 - 0.045 14.2 24.3 0.11 12.9 24.3 1.7 1 0 0 1 1 1 0 Gene product 67 Kisspeptin PF15152.6 EKX33362.1 - 0.14 12.9 0.2 0.32 11.8 0.2 1.5 1 0 0 1 1 1 0 Kisspeptin LAP1C PF05609.12 EKX33362.1 - 0.21 10.6 2.3 0.37 9.8 1.6 1.7 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Nop14 PF04147.12 EKX33362.1 - 0.25 9.5 16.4 0.35 9.0 16.4 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EKX33362.1 - 0.25 9.6 14.9 0.43 8.8 14.9 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF4637 PF15470.6 EKX33362.1 - 0.44 10.3 8.9 0.78 9.4 8.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Cwf_Cwc_15 PF04889.12 EKX33362.1 - 0.59 9.8 15.3 0.98 9.1 15.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sporozoite_P67 PF05642.11 EKX33362.1 - 0.77 7.8 7.6 1.1 7.2 7.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_phi PF04931.13 EKX33362.1 - 2.3 6.2 23.1 3.5 5.6 23.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 EKX33362.1 - 2.4 7.5 17.5 3.6 6.9 17.5 1.2 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 EKX33362.1 - 4.3 6.6 19.5 8.9 5.5 19.5 1.5 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 EKX33362.1 - 6.4 5.8 25.0 9.7 5.2 25.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.13 EKX33362.1 - 8.4 6.2 17.2 0.46 10.3 11.7 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Nop53 PF07767.11 EKX33362.1 - 9.9 5.4 11.1 16 4.8 11.1 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Myb_DNA-binding PF00249.31 EKX33363.1 - 1.5e-06 28.3 0.0 5.2e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 Myb-like DNA-binding domain Aminotran_3 PF00202.21 EKX33366.1 - 1.5e-24 86.5 0.0 2e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III RWP-RK PF02042.15 EKX33367.1 - 3.9e-10 39.6 0.5 1e-09 38.2 0.0 1.9 2 1 1 3 3 3 1 RWP-RK domain RWP-RK PF02042.15 EKX33368.1 - 7e-12 45.1 0.0 1.2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_17 PF12728.7 EKX33368.1 - 0.061 13.5 1.2 0.28 11.4 1.0 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain RasGEF PF00617.19 EKX33369.1 - 1.1e-28 100.6 1.1 1.9e-28 99.9 0.2 2.0 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EKX33369.1 - 1.6e-08 34.7 0.0 5e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif Zip PF02535.22 EKX33370.1 - 0.027 13.7 34.1 0.032 13.4 34.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Pex14_N PF04695.13 EKX33370.1 - 0.047 14.3 19.3 0.066 13.9 19.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM60A PF15396.6 EKX33370.1 - 0.075 13.0 17.6 0.081 12.9 17.6 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Dsh_C PF12316.8 EKX33370.1 - 0.1 13.0 19.6 0.13 12.6 19.6 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Tim54 PF11711.8 EKX33370.1 - 0.58 8.9 13.7 0.7 8.6 13.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Sec62 PF03839.16 EKX33370.1 - 1.4 8.4 19.3 1.5 8.3 19.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Presenilin PF01080.17 EKX33370.1 - 1.4 7.6 24.4 1.5 7.5 24.4 1.0 1 0 0 1 1 1 0 Presenilin DUF4638 PF15472.6 EKX33370.1 - 1.6 8.4 17.5 1.9 8.1 17.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Rtf2 PF04641.12 EKX33370.1 - 2.2 7.5 21.1 2.7 7.3 21.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger MDM10 PF12519.8 EKX33370.1 - 2.3 7.0 17.5 2.5 6.8 17.5 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 ALMT PF11744.8 EKX33370.1 - 2.5 6.8 19.5 2.7 6.7 19.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 EKX33370.1 - 2.7 6.9 21.9 2.8 6.9 21.9 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Dynactin_p62 PF05502.13 EKX33370.1 - 2.7 6.7 14.6 3.2 6.4 14.6 1.0 1 0 0 1 1 1 0 Dynactin p62 family Gti1_Pac2 PF09729.9 EKX33370.1 - 3.3 7.8 21.8 4.2 7.4 21.8 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family DUF4050 PF13259.6 EKX33370.1 - 3.7 7.8 17.5 4.8 7.5 17.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) PAT1 PF09770.9 EKX33370.1 - 5.1 5.2 34.8 5.9 5.0 34.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.12 EKX33370.1 - 5.4 6.8 22.0 6.1 6.6 22.0 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Otopetrin PF03189.13 EKX33370.1 - 7.2 5.3 18.6 8.2 5.1 18.6 1.1 1 0 0 1 1 1 0 Otopetrin Cellulose_synt PF03552.14 EKX33370.1 - 8.1 4.8 6.4 8.5 4.7 6.4 1.1 1 0 0 1 1 1 0 Cellulose synthase Pox_Ag35 PF03286.14 EKX33370.1 - 8.4 6.1 11.0 11 5.8 11.0 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4746 PF15928.5 EKX33370.1 - 8.5 5.7 14.9 11 5.4 14.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4045 PF13254.6 EKX33370.1 - 9.6 5.7 18.7 11 5.5 18.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CKAP2_C PF15297.6 EKX33370.1 - 9.9 5.1 13.9 14 4.6 13.9 1.2 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus A_deaminase PF00962.22 EKX33373.1 - 2.4e-111 372.2 0.1 2.8e-111 372.0 0.1 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF1965 PF09248.10 EKX33373.1 - 0.065 13.0 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) Ion_trans_2 PF07885.16 EKX33374.1 - 0.0079 16.1 4.1 0.029 14.3 4.1 2.0 1 0 0 1 1 1 1 Ion channel RWP-RK PF02042.15 EKX33375.1 - 2e-24 85.3 0.0 2.6e-13 49.7 0.0 2.3 2 0 0 2 2 2 2 RWP-RK domain HTH_8 PF02954.19 EKX33375.1 - 0.01 15.6 5.8 0.64 9.8 0.1 3.6 4 0 0 4 4 4 0 Bacterial regulatory protein, Fis family HTH_3 PF01381.22 EKX33375.1 - 0.045 13.8 0.2 0.57 10.3 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix HTH_Mga PF08280.11 EKX33375.1 - 0.056 13.5 1.2 3.5 7.7 0.2 2.4 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_6 PF01418.17 EKX33375.1 - 0.061 13.3 0.0 7.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family HTH_24 PF13412.6 EKX33375.1 - 0.15 11.7 0.2 7.7 6.2 0.1 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding RWP-RK PF02042.15 EKX33376.1 - 7.2e-09 35.5 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain BUD22 PF09073.10 EKX33377.1 - 0.12 11.7 44.9 0.15 11.4 44.9 1.0 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 EKX33377.1 - 0.17 10.6 24.0 0.24 10.1 24.0 1.3 1 0 0 1 1 1 0 Presenilin DUF5523 PF17661.1 EKX33377.1 - 0.62 9.7 34.4 0.89 9.2 34.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Plasmodium_Vir PF05795.11 EKX33377.1 - 0.72 9.2 11.1 1 8.7 11.1 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Nop14 PF04147.12 EKX33377.1 - 2.2 6.4 55.5 2.6 6.1 55.5 1.0 1 0 0 1 1 1 0 Nop14-like family Caldesmon PF02029.15 EKX33377.1 - 2.3 6.9 37.7 2.6 6.7 37.7 1.0 1 0 0 1 1 1 0 Caldesmon ALMT PF11744.8 EKX33377.1 - 6.1 5.6 13.4 8.6 5.1 13.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 EKX33377.1 - 8.6 5.3 23.3 10 5.0 23.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 RWP-RK PF02042.15 EKX33378.1 - 1e-08 35.0 0.0 1.6e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX33379.1 - 1e-08 35.0 0.0 1.6e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX33380.1 - 3.6e-11 42.8 0.0 6.2e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX33380.1 - 0.13 12.0 0.1 0.61 9.9 0.1 2.0 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family RWP-RK PF02042.15 EKX33381.1 - 1.2e-11 44.4 0.0 1.7e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX33382.1 - 1.2e-11 44.4 0.0 1.7e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain AAA_14 PF13173.6 EKX33383.1 - 0.0022 18.0 0.0 0.0082 16.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EKX33383.1 - 0.0061 17.1 0.0 0.023 15.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EKX33383.1 - 0.012 15.4 0.1 0.08 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EKX33383.1 - 0.022 14.5 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EKX33383.1 - 0.032 14.6 0.1 0.11 12.8 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EKX33383.1 - 0.035 13.7 0.1 0.1 12.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EKX33383.1 - 0.035 14.5 0.0 0.1 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EKX33383.1 - 0.064 13.7 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EKX33383.1 - 0.072 12.8 0.2 0.45 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EKX33383.1 - 0.13 11.9 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Ion_trans_2 PF07885.16 EKX33385.1 - 1.2e-11 44.4 1.3 1.2e-11 44.4 1.3 2.3 3 0 0 3 3 3 1 Ion channel Ion_trans PF00520.31 EKX33385.1 - 2.7e-10 39.9 17.9 4.4e-10 39.2 17.9 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 EKX33385.1 - 5.8e-06 26.3 0.0 1.4e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain NAD_binding_8 PF13450.6 EKX33387.1 - 4.4e-15 55.7 0.3 8.6e-15 54.7 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EKX33387.1 - 1.7e-13 50.7 0.0 2e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 EKX33387.1 - 4.6e-07 29.4 0.0 5.2e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EKX33387.1 - 4.2e-06 26.1 1.1 6.3e-06 25.5 1.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EKX33387.1 - 0.00034 20.3 0.0 0.00054 19.6 0.0 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EKX33387.1 - 0.00069 20.1 0.2 0.0016 18.9 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EKX33387.1 - 0.0022 17.3 0.2 0.0033 16.7 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EKX33387.1 - 0.0083 15.5 0.8 0.012 14.9 0.8 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EKX33387.1 - 0.014 14.7 0.1 0.021 14.1 0.1 1.2 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 EKX33387.1 - 0.045 12.8 2.3 0.05 12.7 1.6 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 EKX33387.1 - 0.058 12.1 0.3 0.084 11.6 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 EKX33387.1 - 0.11 12.5 0.2 0.34 10.9 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 EKX33387.1 - 0.21 10.8 0.4 0.32 10.2 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1824 PF08854.10 EKX33388.1 - 2.3e-12 46.9 0.0 3.4e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1824) Pantoate_ligase PF02569.15 EKX33389.1 - 6.5e-100 333.7 0.0 8e-100 333.4 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase DAO PF01266.24 EKX33390.1 - 3.3e-54 184.8 0.0 3.8e-54 184.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EKX33390.1 - 0.002 17.4 0.3 0.081 12.1 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EKX33390.1 - 0.018 15.3 0.5 0.036 14.3 0.5 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EKX33390.1 - 0.18 11.0 0.5 1.8 7.7 0.3 1.9 2 0 0 2 2 2 0 FAD binding domain TPR_11 PF13414.6 EKX33391.1 - 4.5e-09 35.8 0.1 9.3e-06 25.2 0.0 4.0 4 0 0 4 4 4 1 TPR repeat TPR_14 PF13428.6 EKX33391.1 - 1.2e-07 31.9 0.8 0.0095 16.7 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX33391.1 - 1.8e-07 30.7 0.2 0.017 15.2 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX33391.1 - 6.6e-06 25.7 0.5 0.0032 17.2 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX33391.1 - 2.4e-05 24.7 3.7 0.068 13.7 0.1 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX33391.1 - 4e-05 23.5 0.3 0.0007 19.6 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX33391.1 - 5.8e-05 23.3 0.9 0.00023 21.4 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX33391.1 - 0.00022 21.8 0.0 0.031 14.9 0.0 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX33391.1 - 0.0003 20.6 0.0 0.099 12.7 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX33391.1 - 0.00093 19.0 0.1 0.12 12.3 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX33391.1 - 0.0072 16.9 0.7 23 5.9 0.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_5 PF12688.7 EKX33391.1 - 0.04 14.1 0.0 0.098 12.9 0.0 1.7 1 0 0 1 1 1 0 Tetratrico peptide repeat TPR_9 PF13371.6 EKX33391.1 - 0.049 13.8 0.9 0.31 11.2 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat GreA_GreB_N PF03449.15 EKX33391.1 - 0.061 13.5 0.0 0.23 11.6 0.0 2.0 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal TPR_17 PF13431.6 EKX33391.1 - 0.12 12.8 0.2 10 6.7 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat C2 PF00168.30 EKX33392.1 - 1.1e-08 35.3 0.0 0.0026 18.0 0.0 2.6 2 0 0 2 2 2 2 C2 domain IPK PF03770.16 EKX33392.1 - 0.00011 22.1 0.3 0.00024 21.0 0.3 1.6 2 0 0 2 2 2 1 Inositol polyphosphate kinase PXA PF02194.15 EKX33392.1 - 0.04 13.9 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 PXA domain tRNA-synt_2b PF00587.25 EKX33394.1 - 5.6e-19 68.8 0.0 1.6e-18 67.3 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.11 EKX33394.1 - 3.1e-18 65.8 1.9 5.5e-18 64.9 0.9 2.0 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 EKX33394.1 - 1.9e-17 63.2 0.1 4.2e-17 62.1 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain ELO PF01151.18 EKX33396.1 - 1.7e-52 178.4 29.1 2e-52 178.2 29.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Glycos_transf_2 PF00535.26 EKX33397.1 - 0.058 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Sec34 PF04136.15 EKX33398.1 - 0.026 14.4 3.5 0.35 10.7 0.2 2.5 2 0 0 2 2 2 0 Sec34-like family Spc7 PF08317.11 EKX33398.1 - 0.076 11.9 18.9 0.074 11.9 6.6 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 EKX33398.1 - 0.66 9.3 25.6 0.13 11.6 6.8 3.2 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding DUF4200 PF13863.6 EKX33398.1 - 1.3 9.5 19.3 0.51 10.8 7.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) YabA PF06156.13 EKX33398.1 - 4.5 8.0 8.7 4.2 8.1 1.0 2.6 2 0 0 2 2 2 0 Initiation control protein YabA MCU PF04678.13 EKX33398.1 - 8.6 6.4 8.8 1.1 9.3 0.6 2.4 2 0 0 2 2 2 0 Mitochondrial calcium uniporter PX PF00787.24 EKX33399.1 - 4.1e-12 46.1 0.1 6.1e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 PX domain zf-CCHC_2 PF13696.6 EKX33402.1 - 0.00023 20.9 0.8 0.00034 20.4 0.8 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF4589 PF15252.6 EKX33402.1 - 0.021 14.9 2.0 0.077 13.0 2.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4589) zf-C2H2_10 PF16588.5 EKX33402.1 - 0.03 14.1 3.5 0.054 13.2 3.5 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger RecX PF02631.16 EKX33402.1 - 0.054 14.0 2.1 0.11 13.0 2.1 1.4 1 0 0 1 1 1 0 RecX family zf-CCHC PF00098.23 EKX33402.1 - 0.1 12.7 1.7 0.17 12.0 1.7 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 EKX33402.1 - 0.28 11.0 0.8 0.45 10.3 0.8 1.3 1 0 0 1 1 1 0 Zinc knuckle SMC_N PF02463.19 EKX33404.1 - 6.4e-39 133.7 72.0 1.1e-20 74.0 29.0 3.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EKX33404.1 - 3.2e-27 95.2 0.0 1.4e-26 93.1 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EKX33404.1 - 6.3e-14 52.9 8.7 6.3e-14 52.9 8.7 7.1 2 2 4 6 6 6 1 AAA domain AAA_21 PF13304.6 EKX33404.1 - 8.4e-13 48.8 13.0 6.4e-08 32.8 0.1 4.4 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EKX33404.1 - 7.6e-06 25.6 0.0 1.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EKX33404.1 - 9e-06 25.6 38.9 9e-06 25.6 38.9 4.5 2 2 1 3 3 3 1 AAA ATPase domain OmpH PF03938.14 EKX33404.1 - 0.0014 19.0 8.4 0.0014 19.0 8.4 9.8 3 2 6 9 9 9 1 Outer membrane protein (OmpH-like) ABC_tran_CTD PF16326.5 EKX33404.1 - 0.004 17.4 1.5 0.004 17.4 1.5 11.6 6 3 4 10 10 10 3 ABC transporter C-terminal domain SbcCD_C PF13558.6 EKX33404.1 - 0.0074 16.5 0.0 0.038 14.2 0.0 2.3 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit TPR_2 PF07719.17 EKX33405.1 - 8.6e-20 69.2 16.4 0.0047 16.9 0.0 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 EKX33405.1 - 5.7e-19 67.1 8.5 0.00019 21.1 0.0 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 EKX33405.1 - 8.5e-11 41.4 2.6 0.028 14.1 0.1 5.1 5 0 0 5 5 5 3 TPR repeat TPR_8 PF13181.6 EKX33405.1 - 1.9e-08 33.9 0.1 3 8.3 0.0 6.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX33405.1 - 3.8e-08 33.8 21.5 2e-05 25.1 0.6 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX33405.1 - 1.3e-05 25.6 21.4 0.062 14.1 0.3 6.3 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX33405.1 - 3.9e-05 23.9 15.2 0.49 10.7 0.2 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX33405.1 - 0.00019 21.4 0.8 0.57 10.3 0.3 4.2 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 EKX33405.1 - 0.00049 20.2 12.1 0.14 12.3 0.4 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX33405.1 - 0.0025 17.7 4.6 11 6.3 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat RPN7 PF10602.9 EKX33405.1 - 0.0086 15.8 0.1 0.0086 15.8 0.1 4.2 4 0 0 4 4 4 1 26S proteasome subunit RPN7 CS PF04969.16 EKX33405.1 - 0.01 16.9 0.9 0.019 16.0 0.0 2.0 2 0 0 2 2 2 1 CS domain TPR_6 PF13174.6 EKX33405.1 - 0.014 16.0 9.2 8.4 7.3 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX33405.1 - 0.015 15.8 12.1 2.1 8.9 0.1 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Mito_carr PF00153.27 EKX33406.1 - 4.8e-30 103.3 7.7 6.2e-14 51.7 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein TFIIE_beta PF02186.15 EKX33406.1 - 0.044 14.1 0.0 0.072 13.4 0.0 1.3 1 0 0 1 1 1 0 TFIIE beta subunit core domain SPX PF03105.19 EKX33407.1 - 0.0022 18.0 0.2 0.0025 17.8 0.2 1.1 1 0 0 1 1 1 1 SPX domain Ephrin_rec_like PF07699.13 EKX33407.1 - 0.0043 16.8 5.0 0.0043 16.8 5.0 2.3 2 0 0 2 2 2 1 Putative ephrin-receptor like Apt1 PF10351.9 EKX33407.1 - 0.074 11.9 7.6 0.093 11.6 7.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Raftlin PF15250.6 EKX33407.1 - 0.49 9.1 4.5 0.66 8.7 4.5 1.1 1 0 0 1 1 1 0 Raftlin Macoilin PF09726.9 EKX33407.1 - 1.2 7.6 14.9 1.6 7.2 14.9 1.1 1 0 0 1 1 1 0 Macoilin family DUF4614 PF15391.6 EKX33407.1 - 1.8 8.5 15.4 2.9 7.9 15.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Sec3_C PF09763.9 EKX33407.1 - 5.2 5.3 7.1 6.9 4.9 7.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 HEAT_2 PF13646.6 EKX33408.1 - 9.9e-07 29.1 1.1 1.7 9.1 0.0 4.2 4 0 0 4 4 4 3 HEAT repeats Pkinase PF00069.25 EKX33409.1 - 4.7e-74 249.1 0.0 5.6e-74 248.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX33409.1 - 2.4e-38 131.9 0.0 3.1e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX33409.1 - 1.7e-05 24.3 0.0 2.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EKX33409.1 - 0.003 16.9 0.0 0.035 13.5 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EKX33409.1 - 0.041 12.8 0.3 0.065 12.2 0.3 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EKX33409.1 - 0.058 12.4 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FancD2 PF14631.6 EKX33412.1 - 6e-05 20.7 1.0 6e-05 20.7 1.0 1.5 1 1 1 2 2 2 1 Fanconi anaemia protein FancD2 nuclease Acetyltransf_1 PF00583.25 EKX33413.1 - 2.3e-07 31.0 0.0 3.3e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EKX33413.1 - 8.5e-07 29.0 0.0 1.6e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EKX33413.1 - 1.9e-06 28.2 0.0 2.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EKX33413.1 - 0.0053 16.8 0.0 0.0084 16.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EKX33413.1 - 0.061 13.5 0.0 0.089 12.9 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase AstA PF04958.12 EKX33413.1 - 0.17 10.4 0.0 0.44 9.1 0.0 1.6 2 0 0 2 2 2 0 Arginine N-succinyltransferase beta subunit Toxin_GhoT_OrtT PF10753.9 EKX33413.1 - 0.18 12.0 0.2 0.18 12.0 0.2 1.8 2 0 0 2 2 2 0 Toxin GhoT_OrtT Ank_2 PF12796.7 EKX33414.1 - 6.9e-20 71.4 0.4 6.7e-10 39.4 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX33414.1 - 1.7e-18 66.8 0.9 5.6e-08 33.2 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX33414.1 - 1.7e-18 66.2 1.5 3.6e-06 27.2 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EKX33414.1 - 1e-17 64.0 0.6 2.1e-06 27.9 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX33414.1 - 6.5e-16 56.8 0.1 0.0028 18.0 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Myb_DNA-bind_5 PF13873.6 EKX33415.1 - 0.034 14.2 0.3 0.034 14.2 0.3 4.1 4 0 0 4 4 4 0 Myb/SANT-like DNA-binding domain Amastin PF07344.11 EKX33415.1 - 0.15 11.9 0.3 0.53 10.1 0.3 1.9 1 0 0 1 1 1 0 Amastin surface glycoprotein Herpes_pp85 PF04637.12 EKX33416.1 - 2.1 6.7 5.0 2.7 6.3 5.0 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF2002 PF09400.10 EKX33417.1 - 0.098 12.7 0.0 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2002) Eclosion PF04736.12 EKX33417.1 - 0.17 11.6 1.4 0.31 10.8 1.4 1.3 1 0 0 1 1 1 0 Eclosion hormone SMP_2 PF10144.9 EKX33418.1 - 0.03 14.0 0.0 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Bacterial virulence factor haemolysin zf-C4 PF00105.18 EKX33420.1 - 0.36 11.3 2.5 0.55 10.7 1.0 2.1 2 0 0 2 2 2 0 Zinc finger, C4 type (two domains) Asparaginase_2 PF01112.18 EKX33422.1 - 1.9e-18 66.5 0.3 2.1e-18 66.4 0.3 1.0 1 0 0 1 1 1 1 Asparaginase Ribosomal_L27A PF00828.19 EKX33423.1 - 2.7e-22 79.8 0.3 3.5e-22 79.5 0.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A SET PF00856.28 EKX33424.1 - 1.1e-12 48.7 0.0 1.3e-12 48.4 0.0 1.2 1 0 0 1 1 1 1 SET domain Cobalamin_bind PF01122.19 EKX33424.1 - 0.0083 15.1 0.3 0.013 14.4 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic cobalamin-binding protein Tnp_zf-ribbon_2 PF13842.6 EKX33424.1 - 2.9 8.8 12.0 29 5.6 7.6 3.3 2 1 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Sortilin-Vps10 PF15902.5 EKX33425.1 - 3e-77 260.3 1.8 1.5e-40 139.3 0.2 2.5 2 1 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EKX33425.1 - 1.8e-33 116.3 1.5 3.4e-33 115.4 1.5 1.5 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal PSII_BNR PF14870.6 EKX33425.1 - 0.00088 18.6 0.7 1.2 8.4 0.0 3.4 2 1 1 3 3 3 2 Photosynthesis system II assembly factor YCF48 BNR PF02012.20 EKX33425.1 - 0.0031 17.2 14.2 1.8 8.9 0.0 6.4 6 0 0 6 6 6 1 BNR/Asp-box repeat BNR_6 PF15899.5 EKX33425.1 - 2.5 8.4 5.5 33 4.9 0.0 4.2 4 0 0 4 4 4 0 BNR-Asp box repeat PB1 PF00564.24 EKX33426.1 - 3.2e-08 33.4 0.0 5.9e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 PB1 domain HTH_Crp_2 PF13545.6 EKX33426.1 - 0.00018 21.4 0.1 0.00038 20.4 0.1 1.5 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain Sigma70_r4 PF04545.16 EKX33426.1 - 0.019 14.5 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_37 PF13744.6 EKX33426.1 - 0.042 13.8 0.1 0.082 12.9 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Trypan_PARP PF05887.11 EKX33426.1 - 0.061 13.3 2.4 0.1 12.6 2.4 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Mito_carr PF00153.27 EKX33427.1 - 9.4e-27 92.8 5.2 7.4e-11 41.8 0.2 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein DSPc PF00782.20 EKX33428.1 - 2e-07 30.9 0.0 2.6e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX33428.1 - 1.1e-05 25.1 0.0 1.1e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX33428.1 - 7.2e-05 22.9 0.0 9.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EKX33428.1 - 0.0056 16.7 0.0 0.006 16.6 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EKX33428.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family POTRA_TamA_1 PF17243.2 EKX33429.1 - 0.11 12.6 0.4 1.3 9.2 0.0 2.8 3 0 0 3 3 3 0 POTRA domain TamA domain 1 XG_FTase PF03254.13 EKX33430.1 - 0.0017 17.1 1.8 0.04 12.5 0.0 3.2 4 0 0 4 4 4 1 Xyloglucan fucosyltransferase O-FucT PF10250.9 EKX33430.1 - 0.17 11.6 6.2 1.3 8.6 0.0 4.1 5 0 0 5 5 5 0 GDP-fucose protein O-fucosyltransferase LRR_4 PF12799.7 EKX33434.1 - 3.3e-14 52.7 16.1 1.1e-07 32.1 0.9 2.5 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX33434.1 - 1.7e-08 34.1 10.8 1.6e-07 31.0 3.9 1.9 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 EKX33434.1 - 0.00013 21.7 4.6 0.054 13.6 0.0 3.0 3 0 0 3 3 3 2 Leucine Rich repeat LRR_9 PF14580.6 EKX33434.1 - 0.00072 19.1 1.0 0.0011 18.5 0.8 1.4 1 1 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 EKX33434.1 - 0.0065 16.9 6.1 2.8 8.8 0.2 3.5 3 0 0 3 3 3 2 Leucine Rich Repeat Fez1 PF06818.15 EKX33435.1 - 0.32 11.4 6.9 0.11 12.9 3.5 1.8 2 0 0 2 2 2 0 Fez1 Allexi_40kDa PF05549.11 EKX33435.1 - 0.54 9.7 2.7 0.33 10.4 0.6 1.6 2 0 0 2 2 2 0 Allexivirus 40kDa protein Globin PF00042.22 EKX33440.1 - 3.6e-05 24.3 0.0 0.00041 20.9 0.0 2.1 1 1 0 1 1 1 1 Globin MIF PF01187.18 EKX33440.1 - 0.072 13.4 0.0 0.092 13.0 0.0 1.2 1 0 0 1 1 1 0 Macrophage migration inhibitory factor (MIF) Cyt-b5 PF00173.28 EKX33441.1 - 1.4e-15 57.2 0.1 1.5e-15 57.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Bac_rhodopsin PF01036.18 EKX33442.1 - 2.6e-13 50.1 8.0 4e-13 49.5 8.0 1.3 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF2269 PF10027.9 EKX33442.1 - 0.0018 18.3 4.4 0.0043 17.1 4.4 1.5 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2269) DUF3810 PF12725.7 EKX33442.1 - 0.56 9.5 6.2 0.22 10.8 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Ras PF00071.22 EKX33443.1 - 2.7e-49 166.9 0.0 3.2e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EKX33443.1 - 5.5e-30 104.0 0.0 1e-29 103.2 0.0 1.4 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EKX33443.1 - 1.2e-10 41.1 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EKX33443.1 - 2.2e-05 24.5 0.0 0.0024 17.9 0.0 2.1 1 1 1 2 2 2 2 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EKX33443.1 - 0.0011 18.3 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EKX33443.1 - 0.0022 17.9 0.2 2.4 8.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase RNA_helicase PF00910.22 EKX33443.1 - 0.0022 18.3 0.1 0.016 15.6 0.1 2.1 1 1 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 EKX33443.1 - 0.0099 15.6 0.1 0.024 14.4 0.1 1.6 1 1 1 2 2 2 1 AAA domain GTP_EFTU PF00009.27 EKX33443.1 - 0.014 15.0 0.3 0.036 13.6 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain G-alpha PF00503.20 EKX33443.1 - 0.021 14.0 1.3 0.71 9.0 0.1 2.5 2 1 1 3 3 3 0 G-protein alpha subunit AAA_7 PF12775.7 EKX33443.1 - 0.022 14.3 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ArgoMid PF16487.5 EKX33443.1 - 0.042 14.1 0.1 0.09 13.0 0.1 1.6 1 1 0 1 1 1 0 Mid domain of argonaute AAA_16 PF13191.6 EKX33443.1 - 0.042 14.2 0.0 0.061 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 EKX33443.1 - 0.044 13.1 0.2 0.08 12.2 0.0 1.5 2 0 0 2 2 2 0 Septin ATP_bind_1 PF03029.17 EKX33443.1 - 0.099 12.4 0.4 12 5.5 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF815 PF05673.13 EKX33443.1 - 0.12 11.5 0.0 0.29 10.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FixO PF02433.15 EKX33443.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO TsaE PF02367.17 EKX33443.1 - 0.15 12.1 0.1 0.32 11.0 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Claudin_2 PF13903.6 EKX33444.1 - 0.024 14.4 1.6 0.042 13.6 1.6 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Epimerase PF01370.21 EKX33445.1 - 3.6e-17 62.6 0.0 6e-16 58.6 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EKX33445.1 - 0.00035 19.8 0.1 0.21 10.7 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EKX33445.1 - 0.0037 16.7 0.1 0.075 12.4 0.0 2.3 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Aminotran_3 PF00202.21 EKX33447.1 - 1.5e-71 241.2 0.0 1.9e-71 240.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EKX33447.1 - 0.00072 18.8 0.0 0.11 11.7 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II ATG16 PF08614.11 EKX33448.1 - 0.02 15.1 9.0 0.026 14.7 9.0 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 EKX33448.1 - 0.32 11.5 10.1 0.77 10.3 0.3 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region YabA PF06156.13 EKX33448.1 - 0.39 11.4 4.5 0.91 10.2 4.5 1.6 1 0 0 1 1 1 0 Initiation control protein YabA Spc24 PF08286.11 EKX33448.1 - 2.6 8.3 10.3 4.7 7.5 3.4 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Pkinase PF00069.25 EKX33449.1 - 1.2e-22 80.5 0.0 1.5e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX33449.1 - 7.3e-10 38.6 0.0 1.2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX33449.1 - 0.00034 19.5 0.0 0.00044 19.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX33449.1 - 0.0024 17.8 0.0 0.034 14.1 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EKX33449.1 - 0.02 14.2 0.1 2.3 7.5 0.0 2.6 2 1 0 2 2 2 0 Kinase-like Kdo PF06293.14 EKX33449.1 - 0.06 12.7 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 EKX33449.1 - 0.094 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Atx10homo_assoc PF09759.9 EKX33450.1 - 1.7e-12 47.2 1.3 8.3e-05 22.5 0.1 4.1 2 2 1 4 4 4 4 Spinocerebellar ataxia type 10 protein domain Anti-adapt_IraP PF10796.9 EKX33450.1 - 0.076 13.6 1.9 0.17 12.5 0.8 2.1 2 0 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein HEAT PF02985.22 EKX33450.1 - 0.22 11.9 1.9 98 3.6 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat Atx10homo_assoc PF09759.9 EKX33451.1 - 2.2e-12 46.8 1.4 0.00014 21.8 0.1 3.9 2 2 1 3 3 3 3 Spinocerebellar ataxia type 10 protein domain Rrf2 PF02082.20 EKX33451.1 - 0.028 14.8 0.3 2.2 8.7 0.0 3.0 2 1 1 3 3 3 0 Transcriptional regulator DUF4630 PF15443.6 EKX33451.1 - 0.062 13.5 2.2 13 6.0 0.1 3.4 1 1 2 4 4 4 0 Domain of unknown function (DUF4630) VapB_antitoxin PF09957.9 EKX33451.1 - 0.11 12.4 1.5 0.19 11.7 0.2 2.2 2 0 0 2 2 2 0 Bacterial antitoxin of type II TA system, VapB HEAT PF02985.22 EKX33451.1 - 0.2 12.0 2.1 1.1e+02 3.5 0.0 4.2 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.6 EKX33451.1 - 0.35 11.4 2.5 14 6.4 0.1 3.8 4 1 0 4 4 4 0 HEAT-like repeat Ion_trans PF00520.31 EKX33452.1 - 1e-11 44.6 6.3 3e-11 43.0 6.3 1.6 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX33452.1 - 7.9e-10 38.6 5.1 7.9e-10 38.6 5.1 2.2 3 0 0 3 3 3 1 Ion channel PH PF00169.29 EKX33452.1 - 0.0002 21.8 0.0 0.047 14.2 0.0 2.4 2 0 0 2 2 2 2 PH domain Sec3-PIP2_bind PF15277.6 EKX33452.1 - 0.0088 16.1 0.1 0.018 15.1 0.1 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH CorA PF01544.18 EKX33453.1 - 0.024 14.0 0.1 0.024 14.0 0.1 2.2 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein CENP-B_dimeris PF09026.10 EKX33453.1 - 0.16 12.4 32.9 0.23 11.9 19.6 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4682 PF15733.5 EKX33454.1 - 1.9e-05 25.2 0.6 3.9e-05 24.3 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4682) Glyco_transf_25 PF01755.17 EKX33455.1 - 0.013 15.4 0.0 0.05 13.5 0.0 2.0 1 1 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Cep57_MT_bd PF06657.13 EKX33457.1 - 0.015 15.7 14.9 0.29 11.6 0.4 4.2 4 1 1 5 5 5 0 Centrosome microtubule-binding domain of Cep57 Med9 PF07544.13 EKX33457.1 - 0.047 13.8 3.8 0.23 11.6 0.1 3.0 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF1933 PF09147.10 EKX33457.1 - 0.072 12.7 0.0 0.17 11.4 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1933) XhlA PF10779.9 EKX33457.1 - 1.2 9.4 4.5 1.4 9.1 0.1 3.0 2 1 0 3 3 3 0 Haemolysin XhlA DUF4200 PF13863.6 EKX33457.1 - 2.9 8.3 11.8 1.9 8.9 3.6 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) EF-hand_1 PF00036.32 EKX33458.1 - 2.3e-19 67.4 2.6 3.3e-05 23.1 0.1 4.0 3 1 1 4 4 4 3 EF hand EF-hand_6 PF13405.6 EKX33458.1 - 4.3e-18 63.6 1.3 2e-05 24.1 0.0 3.9 2 1 2 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EKX33458.1 - 1.4e-14 52.8 4.4 0.00022 20.6 0.1 4.1 3 1 1 4 4 4 3 EF hand EF-hand_7 PF13499.6 EKX33458.1 - 1.1e-10 41.8 1.8 1.6e-07 31.7 0.3 2.7 1 1 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 EKX33458.1 - 1.6e-10 40.7 4.2 0.00054 19.8 0.0 3.6 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX33458.1 - 0.0083 16.4 0.0 0.014 15.7 0.0 1.3 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 EKX33458.1 - 0.054 13.4 0.1 3.5 7.6 0.0 2.4 2 0 0 2 2 2 0 EF hand EF-hand_4 PF12763.7 EKX33458.1 - 0.23 11.4 1.3 14 5.7 0.1 2.4 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Hist_deacetyl PF00850.19 EKX33460.1 - 2.3e-50 171.8 0.2 2.2e-28 99.7 0.0 2.9 3 1 0 3 3 3 2 Histone deacetylase domain Ank PF00023.30 EKX33460.1 - 1.1e-11 44.6 0.0 0.00018 21.8 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 EKX33460.1 - 1.6e-11 44.6 0.0 3.7e-08 33.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX33460.1 - 1.5e-10 41.4 0.4 0.0002 21.8 0.0 3.5 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX33460.1 - 4.3e-07 30.1 0.2 0.0087 16.4 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX33460.1 - 1.3e-06 28.3 0.0 0.0043 17.4 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat PKD_channel PF08016.12 EKX33461.1 - 4.7e-21 75.0 24.9 2.5e-10 39.6 0.3 2.5 2 1 0 2 2 2 2 Polycystin cation channel DUF3323 PF11796.8 EKX33461.1 - 0.16 11.9 1.3 0.23 11.3 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) Ion_trans PF00520.31 EKX33461.1 - 0.79 8.9 28.8 3 7.0 28.9 2.0 1 1 0 1 1 1 0 Ion transport protein SUI1 PF01253.22 EKX33462.1 - 5.6e-12 46.0 2.5 5e-11 43.0 0.4 2.1 2 0 0 2 2 2 1 Translation initiation factor SUI1 Img2 PF05046.14 EKX33462.1 - 0.17 12.2 2.1 1.4 9.3 2.1 2.1 1 1 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) rRNA_processing PF08524.11 EKX33463.1 - 1.8e-07 31.3 29.5 1.8e-07 31.3 29.5 2.5 1 1 1 2 2 2 1 rRNA processing hnRNP_Q_AcD PF18360.1 EKX33464.1 - 0.00022 21.1 0.0 0.00036 20.4 0.0 1.3 1 0 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain Glyco_transf_25 PF01755.17 EKX33466.1 - 4.1e-05 23.5 0.0 6.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) DNA_pol3_theta PF06440.11 EKX33466.1 - 0.16 11.7 0.1 4 7.2 0.0 2.7 3 0 0 3 3 3 0 DNA polymerase III, theta subunit Troponin PF00992.20 EKX33467.1 - 0.1 12.9 1.6 2.4 8.5 0.1 2.1 1 1 1 2 2 2 0 Troponin Cdc6_C PF09079.11 EKX33468.1 - 0.11 12.5 0.0 6.7 6.8 0.0 2.9 3 0 0 3 3 3 0 CDC6, C terminal winged helix domain Arm PF00514.23 EKX33470.1 - 2.2e-09 37.0 0.0 1.4e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EKX33470.1 - 0.0021 18.0 0.0 0.0059 16.6 0.0 1.8 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 EKX33470.1 - 0.0067 16.9 0.0 0.042 14.4 0.0 2.3 2 1 0 2 2 2 1 HEAT-like repeat Arm_2 PF04826.13 EKX33470.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Armadillo-like CK2S PF15011.6 EKX33471.1 - 0.019 14.8 0.0 0.022 14.7 0.0 1.1 1 0 0 1 1 1 0 Casein Kinase 2 substrate RVT_1 PF00078.27 EKX33472.1 - 1.8e-08 34.2 0.1 3.5e-08 33.3 0.1 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GILT PF03227.16 EKX33476.1 - 7.4e-20 71.2 0.2 1.8e-19 70.0 0.2 1.6 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Acetyltransf_4 PF13420.7 EKX33476.1 - 0.011 15.9 0.5 0.031 14.4 0.5 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4635 PF15466.6 EKX33476.1 - 0.065 12.8 5.9 0.16 11.5 5.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) Hid1 PF12722.7 EKX33476.1 - 0.068 11.3 10.4 0.089 10.9 10.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein KA1 PF02149.19 EKX33476.1 - 0.12 12.2 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Kinase associated domain 1 AAA_12 PF13087.6 EKX33477.1 - 1.1e-29 103.4 0.4 1.2e-29 103.3 0.4 1.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EKX33477.1 - 0.0022 17.8 0.1 0.005 16.6 0.1 1.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EKX33477.1 - 0.022 14.5 0.0 0.023 14.4 0.0 1.0 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase CompInhib_SCIN PF11546.8 EKX33477.1 - 0.05 13.6 0.0 0.06 13.4 0.0 1.1 1 0 0 1 1 1 0 Staphylococcal complement inhibitor SCIN AAA_11 PF13086.6 EKX33478.1 - 2.2e-29 103.0 0.2 2.6e-29 102.8 0.2 1.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EKX33478.1 - 6.3e-09 35.8 0.0 1.1e-08 35.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EKX33478.1 - 3.8e-06 27.3 0.1 4.4e-06 27.1 0.1 1.4 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 EKX33478.1 - 2.6e-05 23.9 0.0 4.7e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 EKX33478.1 - 0.0007 19.5 0.5 0.0012 18.7 0.0 1.7 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.6 EKX33478.1 - 0.0011 19.3 0.1 0.0072 16.6 0.0 2.0 1 1 0 2 2 2 1 AAA domain ResIII PF04851.15 EKX33478.1 - 0.0022 18.0 0.0 0.0034 17.4 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 EKX33478.1 - 0.0063 15.8 0.0 0.0093 15.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 EKX33478.1 - 0.012 16.0 0.1 0.024 15.1 0.0 1.6 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX33478.1 - 0.012 15.9 0.3 0.025 15.0 0.3 1.7 1 1 0 1 1 1 0 AAA ATPase domain DEAD PF00270.29 EKX33478.1 - 0.021 14.6 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase T2SSE PF00437.20 EKX33478.1 - 0.032 13.3 0.0 0.14 11.2 0.0 1.8 1 1 1 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.6 EKX33478.1 - 0.075 13.5 3.2 0.39 11.2 3.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EKX33478.1 - 0.089 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Nup54_57_C PF18570.1 EKX33478.1 - 0.11 12.1 4.0 2.7 7.6 1.8 3.1 2 1 1 3 3 3 0 NUP57/Nup54 C-terminal domain AAA_29 PF13555.6 EKX33478.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3641 PF12345.8 EKX33479.1 - 3.9e-52 175.9 0.1 1e-51 174.5 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3641) Radical_SAM PF04055.21 EKX33479.1 - 5.7e-09 36.6 0.0 1.1e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EKX33479.1 - 1.5e-05 25.3 0.1 3e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain MAD PF05557.13 EKX33481.1 - 3.4e-05 22.4 11.6 3.4e-05 22.4 11.6 2.1 1 1 1 2 2 2 1 Mitotic checkpoint protein Rootletin PF15035.6 EKX33481.1 - 0.007 16.4 3.1 0.007 16.4 3.1 2.3 1 1 1 2 2 2 1 Ciliary rootlet component, centrosome cohesion DUF745 PF05335.13 EKX33481.1 - 0.01 15.6 10.2 0.051 13.3 1.8 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF745) Fib_alpha PF08702.10 EKX33481.1 - 0.011 15.9 1.6 0.011 15.9 1.6 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family BBL5 PF07289.11 EKX33481.1 - 0.031 13.3 0.1 0.052 12.6 0.1 1.4 1 0 0 1 1 1 0 Bardet-Biedl syndrome 5 protein P22_AR_N PF10547.9 EKX33481.1 - 0.031 14.6 2.5 7 7.0 0.0 3.5 1 1 1 3 3 3 0 P22_AR N-terminal domain SlyX PF04102.12 EKX33481.1 - 0.034 14.8 15.4 14 6.4 1.5 4.8 1 1 3 4 4 4 0 SlyX PLA2_inh PF02988.15 EKX33481.1 - 0.037 14.7 5.0 0.19 12.4 0.1 2.9 2 1 2 4 4 4 0 Phospholipase A2 inhibitor BLOC1_2 PF10046.9 EKX33481.1 - 0.056 13.8 13.1 0.77 10.1 0.5 3.3 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mt_ATP-synt_D PF05873.12 EKX33481.1 - 0.056 13.3 2.2 0.1 12.5 1.4 1.8 1 1 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) DUF1664 PF07889.12 EKX33481.1 - 0.065 13.3 0.5 0.065 13.3 0.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 EKX33481.1 - 0.067 13.4 19.1 0.08 13.2 5.8 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GAS PF13851.6 EKX33481.1 - 0.082 12.2 21.7 0.5 9.7 11.2 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding zf-C2H2_9 PF16293.5 EKX33481.1 - 0.1 12.4 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) HrpB7 PF09486.10 EKX33481.1 - 0.22 11.9 12.9 0.85 10.0 1.1 3.2 1 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) LMBR1 PF04791.16 EKX33481.1 - 0.42 9.4 2.3 0.51 9.2 2.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SHE3 PF17078.5 EKX33481.1 - 0.66 9.6 16.8 2.1 8.0 7.1 2.4 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 HAP1_N PF04849.13 EKX33481.1 - 0.78 8.9 23.7 2.4 7.3 10.4 2.2 1 1 1 2 2 2 0 HAP1 N-terminal conserved region SOGA PF11365.8 EKX33481.1 - 0.8 10.9 12.8 8.2 7.6 2.5 3.3 1 1 2 3 3 3 0 Protein SOGA DHR10 PF18595.1 EKX33481.1 - 0.88 9.7 24.2 0.032 14.3 3.9 3.2 1 1 2 3 3 2 0 Designed helical repeat protein 10 domain Phage_Mu_Gam PF07352.12 EKX33481.1 - 1.6 8.6 12.4 0.21 11.5 2.2 2.9 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein PI3K_P85_iSH2 PF16454.5 EKX33481.1 - 1.9 8.1 20.8 0.8 9.3 3.5 2.1 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Fez1 PF06818.15 EKX33481.1 - 2.1 8.8 19.0 0.28 11.6 9.1 2.1 1 1 1 2 2 2 0 Fez1 TSC22 PF01166.18 EKX33481.1 - 2.4 8.5 15.6 12 6.3 1.2 4.7 2 2 3 5 5 5 0 TSC-22/dip/bun family PIN_8 PF18476.1 EKX33481.1 - 2.7 7.8 9.2 5.1 6.9 4.3 2.1 1 1 1 2 2 2 0 PIN like domain Nsp1_C PF05064.13 EKX33481.1 - 3 7.7 11.7 0.72 9.7 3.8 2.8 1 1 2 3 3 3 0 Nsp1-like C-terminal region Exonuc_VII_L PF02601.15 EKX33481.1 - 3.4 7.2 12.9 30 4.1 13.0 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit MSG PF02349.15 EKX33481.1 - 4.2 7.6 19.3 20 5.5 8.8 3.3 1 1 2 3 3 2 0 Major surface glycoprotein DUF4407 PF14362.6 EKX33481.1 - 4.4 6.6 12.3 10 5.4 11.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4094 PF13334.6 EKX33481.1 - 4.7 7.7 7.6 3.3 8.2 0.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) FlxA PF14282.6 EKX33481.1 - 5.3 7.1 15.1 0.35 10.9 3.9 3.1 1 1 0 2 2 2 0 FlxA-like protein Tropomyosin_1 PF12718.7 EKX33481.1 - 6.1 7.0 19.0 16 5.6 5.7 2.8 1 1 1 2 2 2 0 Tropomyosin like DivIC PF04977.15 EKX33481.1 - 6.2 6.7 11.4 6.9 6.5 0.4 3.5 1 1 1 3 3 3 0 Septum formation initiator APG6_N PF17675.1 EKX33481.1 - 6.2 7.3 20.9 3.5 8.1 3.7 2.8 1 1 2 3 3 3 0 Apg6 coiled-coil region Laminin_II PF06009.12 EKX33481.1 - 6.9 6.7 10.6 8.9 6.3 1.0 3.0 1 1 2 4 4 4 0 Laminin Domain II ZapB PF06005.12 EKX33481.1 - 7.7 7.0 22.4 5.3 7.5 0.5 3.8 1 1 2 3 3 2 0 Cell division protein ZapB GIT1_C PF12205.8 EKX33481.1 - 9.8 6.3 12.8 11 6.2 1.3 3.3 1 1 2 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term LRR_8 PF13855.6 EKX33482.1 - 7.4e-67 221.0 73.5 8.3e-10 38.3 0.8 10.1 6 3 5 11 11 11 11 Leucine rich repeat LRR_4 PF12799.7 EKX33482.1 - 3.9e-59 195.6 92.4 3e-07 30.7 3.5 13.0 8 2 4 14 14 14 14 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX33482.1 - 1.3e-11 44.3 40.5 0.035 13.6 0.2 7.4 1 1 8 9 9 9 8 Leucine-rich repeat LRR_1 PF00560.33 EKX33482.1 - 4e-11 41.8 82.4 3.8 8.4 1.2 20.1 19 4 0 19 19 19 4 Leucine Rich Repeat LRR_5 PF13306.6 EKX33482.1 - 2.9e-08 33.7 10.2 0.057 13.4 0.0 5.3 4 2 1 5 5 5 3 BspA type Leucine rich repeat region (6 copies) DUF4571 PF15137.6 EKX33482.1 - 0.0021 17.7 11.6 1.2 8.8 0.1 5.2 2 2 3 6 6 6 2 Domain of unknown function (DUF4571) DUF2482 PF10655.9 EKX33482.1 - 0.0066 16.9 0.8 5.4 7.6 0.1 3.8 4 0 0 4 4 4 1 Hypothetical protein of unknown function (DUF2482) YopH_N PF09013.10 EKX33482.1 - 0.077 13.3 0.2 7.8 6.8 0.0 3.2 3 0 0 3 3 3 0 YopH, N-terminal LRR_6 PF13516.6 EKX33482.1 - 0.084 13.0 0.5 0.69 10.1 0.1 16.0 19 0 0 19 19 19 0 Leucine Rich repeat LRR_8 PF13855.6 EKX33483.1 - 2.9e-12 46.2 11.9 3.3e-06 26.8 6.6 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EKX33483.1 - 8.9e-12 45.0 12.2 4.3e-05 23.8 0.1 3.1 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX33483.1 - 0.00026 20.5 1.4 0.00035 20.1 1.3 1.3 1 1 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 EKX33483.1 - 0.0066 16.8 13.0 33 5.6 0.4 5.2 4 1 0 4 4 4 3 Leucine Rich Repeat LRR_6 PF13516.6 EKX33483.1 - 0.42 10.8 10.7 2.4 8.4 0.1 4.0 4 0 0 4 4 4 0 Leucine Rich repeat LRR_8 PF13855.6 EKX33484.1 - 3.8e-19 68.2 32.7 1.8e-07 30.8 1.7 4.5 1 1 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 EKX33484.1 - 1.9e-14 53.5 29.7 0.0012 19.1 0.0 5.5 2 2 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX33484.1 - 3.4e-06 26.9 14.5 0.91 10.3 0.1 7.5 8 0 0 8 8 8 2 Leucine Rich Repeat LRR_3 PF07725.12 EKX33484.1 - 2.7 8.0 9.5 3.6 7.6 0.9 3.1 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.6 EKX33485.1 - 3.4e-14 52.4 9.7 7.6e-08 32.0 2.9 2.0 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EKX33485.1 - 2.3e-11 43.7 12.4 3.5e-06 27.3 0.5 3.0 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX33485.1 - 0.0023 18.2 5.2 8.1 7.4 0.0 4.4 3 2 1 4 4 4 1 Leucine Rich Repeat DUF4571 PF15137.6 EKX33485.1 - 0.064 12.9 0.1 0.33 10.6 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4571) LRR_6 PF13516.6 EKX33485.1 - 0.28 11.3 0.1 0.28 11.3 0.1 4.1 5 1 0 5 5 5 0 Leucine Rich repeat LRR_8 PF13855.6 EKX33486.1 - 2.3e-54 181.0 132.8 4.1e-09 36.1 2.4 8.8 2 1 9 12 12 12 12 Leucine rich repeat LRR_4 PF12799.7 EKX33486.1 - 2.8e-44 148.3 86.4 3.3e-06 27.3 1.8 11.6 3 2 9 15 15 15 15 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX33486.1 - 1.5e-09 37.6 32.7 0.0016 17.9 0.5 5.9 2 2 5 7 7 7 5 Leucine-rich repeat LRR_1 PF00560.33 EKX33486.1 - 6.6e-05 22.9 56.9 4.3 8.3 0.3 16.3 18 1 1 19 19 19 3 Leucine Rich Repeat LRR_6 PF13516.6 EKX33486.1 - 4.6 7.5 0.0 4 7.8 0.1 13.8 16 0 0 16 16 16 0 Leucine Rich repeat Nuf2 PF03800.14 EKX33487.1 - 9e-42 142.5 0.3 9e-42 142.5 0.3 1.9 2 0 0 2 2 2 1 Nuf2 family GAS PF13851.6 EKX33487.1 - 0.0013 18.2 15.6 0.0021 17.5 15.6 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding THOC7 PF05615.13 EKX33487.1 - 0.0036 17.6 8.8 0.0068 16.7 8.8 1.4 1 0 0 1 1 1 1 Tho complex subunit 7 Atg14 PF10186.9 EKX33487.1 - 0.015 14.4 12.2 0.022 13.9 12.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Lebercilin PF15619.6 EKX33487.1 - 0.027 14.1 17.7 0.037 13.7 17.7 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease APG6_N PF17675.1 EKX33487.1 - 0.032 14.7 15.7 0.052 14.1 15.7 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF3450 PF11932.8 EKX33487.1 - 0.033 13.5 14.1 0.038 13.3 13.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DivIC PF04977.15 EKX33487.1 - 0.094 12.5 12.2 0.044 13.6 5.3 2.5 1 1 1 2 2 2 0 Septum formation initiator zf-C4H2 PF10146.9 EKX33487.1 - 0.12 12.6 10.0 0.18 12.1 10.0 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein UPF0242 PF06785.11 EKX33487.1 - 0.12 12.4 11.1 0.17 12.0 11.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF87 PF01935.17 EKX33487.1 - 0.16 12.1 4.4 0.23 11.6 4.4 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain FapA PF03961.13 EKX33487.1 - 0.16 10.6 8.2 0.2 10.2 8.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Jnk-SapK_ap_N PF09744.9 EKX33487.1 - 0.17 12.1 16.3 0.32 11.2 16.3 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Takusan PF04822.13 EKX33487.1 - 0.24 11.3 11.4 1.2 9.1 1.2 3.3 1 1 2 3 3 3 0 Takusan DUF4337 PF14235.6 EKX33487.1 - 0.36 10.9 6.8 0.51 10.4 6.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF4200 PF13863.6 EKX33487.1 - 0.39 11.1 17.1 0.78 10.2 17.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Uso1_p115_C PF04871.13 EKX33487.1 - 0.45 10.9 13.0 0.68 10.3 13.0 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Seryl_tRNA_N PF02403.22 EKX33487.1 - 0.48 10.7 12.5 1.1 9.5 12.5 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Prefoldin PF02996.17 EKX33487.1 - 0.51 10.3 12.3 1.1 9.2 2.1 2.3 1 1 1 2 2 2 0 Prefoldin subunit Cnn_1N PF07989.11 EKX33487.1 - 0.59 10.3 15.7 0.05 13.8 4.9 3.0 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 DUF1664 PF07889.12 EKX33487.1 - 0.64 10.1 7.1 1.1 9.3 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 EKX33487.1 - 0.79 9.7 19.3 4.5 7.3 19.3 1.9 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 EKX33487.1 - 1.5 9.5 12.9 0.98 10.1 10.0 2.1 1 1 1 2 2 2 0 Initiation control protein YabA DUF724 PF05266.14 EKX33487.1 - 1.7 8.4 16.4 1.3 8.8 12.4 2.3 2 1 1 3 3 2 0 Protein of unknown function (DUF724) TMF_DNA_bd PF12329.8 EKX33487.1 - 2 8.5 17.0 1.2 9.2 12.4 2.5 2 1 2 4 4 3 0 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 EKX33487.1 - 2.6 8.6 21.3 3.4 8.2 9.1 2.6 1 1 0 2 2 2 0 Cell division protein ZapB Spc24 PF08286.11 EKX33487.1 - 2.7 8.3 15.8 0.63 10.3 6.7 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 ADIP PF11559.8 EKX33487.1 - 3.1 7.9 17.9 4.5 7.3 8.0 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding PRKG1_interact PF15898.5 EKX33487.1 - 5.3 8.0 15.1 1.7 9.6 5.8 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Csm1_N PF18504.1 EKX33487.1 - 7.8 6.9 16.8 0.68 10.3 7.3 2.4 1 1 1 2 2 2 0 Csm1 N-terminal domain bZIP_1 PF00170.21 EKX33487.1 - 8.6 6.5 13.5 2.5 8.3 7.0 2.4 1 1 1 2 2 2 0 bZIP transcription factor UPF0449 PF15136.6 EKX33487.1 - 8.7 6.9 12.9 1.9 9.0 0.9 2.7 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Josephin PF02099.17 EKX33488.1 - 1e-42 146.0 0.0 1.5e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 Josephin Zn_clus PF00172.18 EKX33489.1 - 0.023 14.8 2.4 0.075 13.2 2.4 1.8 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF155 PF02582.14 EKX33490.1 - 2.1e-36 125.7 0.0 2.8e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 ubiquitin PF00240.23 EKX33491.1 - 0.00056 19.6 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family PepX_N PF09168.10 EKX33494.1 - 0.54 10.7 3.8 1.5 9.3 1.1 2.1 1 1 1 2 2 2 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal DMPK_coil PF08826.10 EKX33494.1 - 0.96 9.6 10.6 1.1 9.4 1.7 2.8 3 0 0 3 3 3 0 DMPK coiled coil domain like EGF_2 PF07974.13 EKX33495.1 - 4.6e-22 78.1 164.5 3.7e-05 24.0 7.5 10.9 7 3 4 11 11 11 7 EGF-like domain hEGF PF12661.7 EKX33495.1 - 8e-15 54.8 110.1 0.0043 17.6 6.3 10.2 9 0 0 9 9 9 6 Human growth factor-like EGF EGF PF00008.27 EKX33495.1 - 1.9e-10 40.8 113.4 0.0039 17.4 2.8 10.0 10 0 0 10 10 10 7 EGF-like domain DSL PF01414.19 EKX33495.1 - 4e-10 39.8 158.0 0.00026 21.2 11.5 9.9 9 1 1 10 10 10 6 Delta serrate ligand Laminin_EGF PF00053.24 EKX33495.1 - 6e-09 35.9 139.7 0.16 12.2 7.0 10.9 2 2 7 10 10 10 7 Laminin EGF domain RepA1_leader PF08048.12 EKX33495.1 - 0.2 12.0 12.4 18 5.7 0.5 4.5 3 0 0 3 3 3 0 Tap RepA1 leader peptide EB PF01683.18 EKX33495.1 - 1.3 9.4 125.9 7.4 7.0 11.6 8.0 1 1 6 7 7 7 0 EB module zf-CCCH_4 PF18044.1 EKX33497.1 - 2.7e-05 23.9 1.8 2.7e-05 23.9 1.8 2.1 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH PF00642.24 EKX33497.1 - 0.00012 21.9 0.4 0.00024 20.9 0.4 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EKX33497.1 - 0.0029 17.6 3.4 0.0029 17.6 3.4 2.4 3 0 0 3 3 3 1 Zinc finger domain Methyltransf_25 PF13649.6 EKX33497.1 - 0.055 14.2 0.0 0.31 11.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain RWP-RK PF02042.15 EKX33498.1 - 0.059 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 RWP-RK domain Lentiviral_Tat PF02998.14 EKX33498.1 - 0.086 12.9 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Lentiviral Tat protein CDT1_C PF16679.5 EKX33498.1 - 0.12 12.8 1.4 0.18 12.3 1.4 1.3 1 1 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain Usp PF00582.26 EKX33499.1 - 1.9e-19 70.6 0.0 4.1e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 Universal stress protein family Styelin PF17562.2 EKX33499.1 - 0.69 10.3 2.6 0.88 10.0 0.3 2.3 2 0 0 2 2 2 0 Styelin GoLoco PF02188.17 EKX33500.1 - 0.057 12.9 0.1 0.14 11.7 0.1 1.7 1 0 0 1 1 1 0 GoLoco motif RRN3 PF05327.11 EKX33500.1 - 0.083 11.4 0.6 0.074 11.6 0.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CENP-B_dimeris PF09026.10 EKX33500.1 - 0.13 12.7 16.8 0.3 11.5 16.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 EKX33500.1 - 0.32 10.6 5.1 0.61 9.7 5.1 1.5 1 0 0 1 1 1 0 FAM176 family DUF4880 PF16220.5 EKX33500.1 - 0.72 9.8 4.1 1.2 9.1 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4880) Myc_N PF01056.18 EKX33500.1 - 1.6 8.5 6.3 2.8 7.7 6.3 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Aminotran_1_2 PF00155.21 EKX33501.1 - 3.8e-39 134.9 0.0 4.6e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EKX33501.1 - 0.0019 16.8 0.0 0.0033 16.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme IspD PF01128.19 EKX33502.1 - 2.2e-53 181.3 0.1 2.6e-53 181.0 0.1 1.0 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NTP_transf_3 PF12804.7 EKX33502.1 - 8.8e-13 48.9 0.0 1.1e-12 48.6 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 EKX33502.1 - 6e-05 22.7 0.0 8e-05 22.3 0.0 1.3 1 1 0 1 1 1 1 Nucleotidyl transferase UDPGP PF01704.18 EKX33502.1 - 0.015 13.9 0.0 0.029 13.0 0.0 1.4 1 0 0 1 1 1 0 UTP--glucose-1-phosphate uridylyltransferase CTP_transf_3 PF02348.19 EKX33502.1 - 0.13 12.1 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase Nramp PF01566.18 EKX33503.1 - 2.3e-107 359.1 11.3 2.3e-107 359.1 11.3 1.9 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein GSG-1 PF07803.11 EKX33503.1 - 0.11 12.4 0.2 0.28 11.1 0.2 1.6 1 0 0 1 1 1 0 GSG1-like protein Na_Ca_ex PF01699.24 EKX33504.1 - 3e-22 79.2 11.0 3.3e-22 79.1 11.0 1.0 1 0 0 1 1 1 1 Sodium/calcium exchanger protein ABC2_membrane_3 PF12698.7 EKX33504.1 - 0.054 12.6 4.4 0.081 12.0 4.4 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein HSP70 PF00012.20 EKX33506.1 - 2.7e-130 435.4 0.0 3.1e-130 435.2 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EKX33506.1 - 3.4e-18 65.6 0.0 3e-16 59.1 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 EKX33506.1 - 0.0043 16.8 0.0 0.008 15.9 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EKX33506.1 - 0.0064 16.9 0.0 5.1 7.6 0.0 2.6 2 2 0 2 2 2 2 Cell division protein FtsA Hydantoinase_A PF01968.18 EKX33506.1 - 0.05 12.9 0.1 1.1 8.4 0.0 2.6 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase DnaJ PF00226.31 EKX33507.1 - 1.8e-20 72.8 3.8 1.9e-20 72.7 3.8 1.0 1 0 0 1 1 1 1 DnaJ domain TPR_MLP1_2 PF07926.12 EKX33509.1 - 0.002 18.2 58.0 0.0029 17.7 18.6 3.2 2 1 1 3 3 3 3 TPR/MLP1/MLP2-like protein Polyoma_coat2 PF00761.20 EKX33509.1 - 1.4 8.5 12.8 0.017 14.9 3.4 2.3 2 1 0 2 2 2 0 Polyomavirus coat protein NPV_P10 PF05531.12 EKX33509.1 - 2.8 8.5 8.6 9.2 6.8 0.2 3.6 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DpnI_C PF17726.1 EKX33509.1 - 4.1 7.6 7.4 7.5 6.8 0.1 3.0 3 0 0 3 3 3 0 Dam-replacing HTH domain FlaC_arch PF05377.11 EKX33509.1 - 7.2 7.1 31.9 0.22 11.9 1.5 5.5 2 1 3 5 5 5 0 Flagella accessory protein C (FlaC) Lectin_C PF00059.21 EKX33510.1 - 0.028 15.1 0.6 0.3 11.8 0.6 2.3 1 1 0 1 1 1 0 Lectin C-type domain Ank_5 PF13857.6 EKX33511.1 - 5.3e-15 55.3 0.8 1.3e-09 38.1 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX33511.1 - 7.8e-14 51.9 0.5 2e-08 34.6 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX33511.1 - 9.7e-13 47.1 0.3 1.9e-05 24.7 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EKX33511.1 - 3.5e-12 46.2 1.1 2.6e-07 30.8 0.6 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EKX33511.1 - 1e-10 42.0 0.1 1.2e-10 41.8 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) DUF1500 PF07389.12 EKX33513.1 - 0.075 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1500) Complex1_LYR_2 PF13233.6 EKX33513.1 - 0.39 11.5 2.2 5.4 7.8 0.0 2.6 1 1 0 2 2 2 0 Complex1_LYR-like Dus PF01207.17 EKX33514.1 - 1e-81 274.5 0.0 1.1e-81 274.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 EKX33514.1 - 0.054 12.7 0.0 0.25 10.5 0.0 1.9 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase SAM_1 PF00536.30 EKX33515.1 - 2.6e-12 47.0 0.2 5.8e-12 45.9 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EKX33515.1 - 2.1e-09 37.4 0.1 4.9e-09 36.2 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Trypan_PARP PF05887.11 EKX33515.1 - 1.7e-06 28.1 16.1 1.7e-06 28.1 16.1 3.2 4 0 0 4 4 4 1 Procyclic acidic repetitive protein (PARP) PH PF00169.29 EKX33515.1 - 0.15 12.6 0.7 0.73 10.4 0.1 2.4 2 0 0 2 2 2 0 PH domain SAS4 PF15460.6 EKX33515.1 - 2.1 8.5 7.1 58 3.9 0.1 3.9 4 0 0 4 4 4 0 Something about silencing, SAS, complex subunit 4 He_PIG PF05345.12 EKX33516.1 - 1.6e-14 53.8 0.9 0.0018 18.4 0.1 3.6 3 0 0 3 3 3 3 Putative Ig domain F5_F8_type_C PF00754.25 EKX33516.1 - 0.0091 16.1 0.0 0.022 14.9 0.0 1.6 1 0 0 1 1 1 1 F5/8 type C domain EF-hand_7 PF13499.6 EKX33516.1 - 0.016 15.6 0.2 0.053 14.0 0.2 1.9 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 EKX33516.1 - 0.19 11.6 0.2 1.1 9.1 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain pair LIM PF00412.22 EKX33517.1 - 1.8e-08 34.4 0.6 6.2e-07 29.6 0.1 2.3 2 0 0 2 2 2 1 LIM domain Coiled PF05710.12 EKX33517.1 - 0.042 14.7 2.8 0.042 14.7 2.8 2.0 2 0 0 2 2 2 0 Coiled coil RAG1_imp_bd PF12560.8 EKX33517.1 - 2.9 7.3 8.6 0.7 9.4 0.3 2.4 2 0 0 2 2 2 0 RAG1 importin binding gag-asp_proteas PF13975.6 EKX33518.1 - 5e-06 27.0 0.1 2.2e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EKX33518.1 - 7e-06 26.6 0.0 1.9e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 EKX33518.1 - 0.021 14.6 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease RVP PF00077.20 EKX33518.1 - 0.045 14.1 0.0 0.098 13.0 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.10 EKX33518.1 - 0.16 11.7 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Asp_protease_2 PF13650.6 EKX33519.1 - 9.4e-07 29.4 0.0 2.2e-06 28.2 0.0 1.6 1 1 1 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 EKX33519.1 - 3.4e-06 27.5 0.1 6.6e-06 26.6 0.1 1.6 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 EKX33519.1 - 0.00079 19.2 0.0 0.0014 18.4 0.0 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2B PF12384.8 EKX33519.1 - 0.014 15.0 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Ty3 transposon peptidase RVP PF00077.20 EKX33519.1 - 0.017 15.4 0.0 0.031 14.6 0.0 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease Peptidase_A2E PF12382.8 EKX33519.1 - 0.047 13.7 0.0 0.062 13.3 0.0 1.1 1 0 0 1 1 1 0 Retrotransposon peptidase Asp_protease PF09668.10 EKX33519.1 - 0.084 12.7 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Mg_chelatase PF01078.21 EKX33520.1 - 3.2e-14 52.8 0.9 1.6e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI VWA_2 PF13519.6 EKX33520.1 - 2.6e-11 44.1 0.0 8.6e-11 42.4 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain Sigma54_activat PF00158.26 EKX33520.1 - 9.3e-08 32.0 0.0 0.0056 16.4 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain MCM PF00493.23 EKX33520.1 - 1.1e-07 31.2 0.0 1.8e-06 27.2 0.0 2.5 2 1 0 2 2 2 1 MCM P-loop domain AAA_lid_2 PF17863.1 EKX33520.1 - 1.3e-06 28.2 0.3 1.3e-06 28.2 0.3 2.2 2 0 0 2 2 1 1 AAA lid domain VWA PF00092.28 EKX33520.1 - 1.5e-05 25.4 0.0 2.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_5 PF07728.14 EKX33520.1 - 1.6e-05 24.9 0.1 0.023 14.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) VWA_3 PF13768.6 EKX33520.1 - 0.00021 21.3 0.1 0.0016 18.4 0.1 2.4 1 1 0 1 1 1 1 von Willebrand factor type A domain Sigma54_activ_2 PF14532.6 EKX33520.1 - 0.0016 18.6 0.0 0.7 10.0 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 EKX33520.1 - 0.0038 17.6 0.1 0.018 15.4 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EKX33520.1 - 0.022 15.0 0.0 0.32 11.3 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_10 PF12846.7 EKX33520.1 - 0.096 11.6 0.1 0.34 9.8 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain TIP49 PF06068.13 EKX33520.1 - 0.16 11.2 0.4 17 4.5 0.2 2.5 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_7 PF12775.7 EKX33520.1 - 0.2 11.1 0.0 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region NOA36 PF06524.12 EKX33520.1 - 0.69 9.2 4.3 1.3 8.3 4.3 1.4 1 0 0 1 1 1 0 NOA36 protein Mpv17_PMP22 PF04117.12 EKX33522.1 - 9.7e-09 35.3 0.0 2e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Inhibitor_Mig-6 PF11555.8 EKX33523.1 - 0.019 15.0 0.3 0.019 15.0 0.3 2.0 3 0 0 3 3 3 0 EGFR receptor inhibitor Mig-6 AAA_11 PF13086.6 EKX33524.1 - 0.00021 21.2 0.2 0.0057 16.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain GvpD PF07088.11 EKX33524.1 - 0.061 11.9 0.0 0.13 10.9 0.0 1.5 2 0 0 2 2 2 0 GvpD gas vesicle protein AAA_25 PF13481.6 EKX33524.1 - 0.11 12.0 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EKX33524.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 EKX33524.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Snapin_Pallidin PF14712.6 EKX33527.1 - 0.00097 19.5 5.2 0.00097 19.5 5.2 3.3 2 1 1 3 3 3 1 Snapin/Pallidin Spc7 PF08317.11 EKX33527.1 - 0.0016 17.4 17.0 0.0016 17.4 17.0 2.3 1 1 1 2 2 2 1 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 EKX33527.1 - 0.011 15.7 15.9 0.011 15.7 15.9 2.8 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CREPT PF16566.5 EKX33527.1 - 0.24 11.6 24.2 0.27 11.4 0.9 3.1 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour SOAR PF16533.5 EKX33527.1 - 0.33 10.9 19.0 0.12 12.4 7.6 3.1 2 1 0 2 2 2 0 STIM1 Orai1-activating region APG6_N PF17675.1 EKX33527.1 - 0.35 11.4 36.9 0.65 10.5 16.7 3.1 1 1 1 2 2 2 0 Apg6 coiled-coil region ERM PF00769.19 EKX33527.1 - 0.43 10.4 30.9 0.028 14.3 21.9 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF2009 PF09418.10 EKX33527.1 - 0.52 9.3 8.7 0.1 11.6 4.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2009) TPR_MLP1_2 PF07926.12 EKX33527.1 - 0.7 10.0 36.0 0.83 9.7 11.7 3.6 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 EKX33527.1 - 0.72 9.9 17.1 0.45 10.6 6.5 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) GAS PF13851.6 EKX33527.1 - 0.92 8.8 28.2 0.27 10.6 17.9 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Sugarporin_N PF11471.8 EKX33527.1 - 1.1 9.3 10.5 0.095 12.7 5.3 2.0 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension WXG100 PF06013.12 EKX33527.1 - 1.5 9.1 14.1 4 7.7 2.7 4.7 3 2 2 5 5 5 0 Proteins of 100 residues with WXG DUF4472 PF14739.6 EKX33527.1 - 1.8 9.3 28.7 0.08 13.7 11.0 3.8 1 1 3 4 4 4 0 Domain of unknown function (DUF4472) FlaC_arch PF05377.11 EKX33527.1 - 1.9 9.0 11.6 1.4 9.4 2.3 4.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) M PF02370.16 EKX33527.1 - 4.5 8.2 11.8 16 6.4 3.7 3.7 1 1 0 2 2 2 0 M protein repeat DUF2730 PF10805.8 EKX33527.1 - 7.1 6.8 12.9 3.7 7.7 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) Baculo_PEP_C PF04513.12 EKX33527.1 - 7.6 6.6 15.0 0.92 9.5 3.9 3.0 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus LPP PF04728.13 EKX33527.1 - 8 6.9 16.9 2.4 8.6 1.1 4.2 3 1 1 5 5 5 0 Lipoprotein leucine-zipper Fez1 PF06818.15 EKX33527.1 - 8.6 6.8 31.4 2 8.8 17.5 2.4 2 0 0 2 2 2 0 Fez1 Arm PF00514.23 EKX33528.1 - 0.0027 17.7 0.3 0.4 10.8 0.0 2.9 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat Cytomega_UL84 PF06284.11 EKX33528.1 - 0.0071 14.9 3.9 0.013 14.0 3.9 1.4 1 0 0 1 1 1 1 Cytomegalovirus UL84 protein SARAF PF06682.12 EKX33528.1 - 0.023 14.3 11.8 0.042 13.5 11.8 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Forkhead_N PF08430.12 EKX33528.1 - 3.7 8.2 13.1 10 6.7 12.7 1.9 1 1 0 1 1 1 0 Forkhead N-terminal region BUD22 PF09073.10 EKX33529.1 - 5.4e-08 32.6 17.3 7.6e-08 32.1 17.3 1.1 1 0 0 1 1 1 1 BUD22 RNA_pol_Rpc4 PF05132.14 EKX33529.1 - 2.6e-06 27.9 1.1 0.069 13.6 0.1 2.2 2 0 0 2 2 2 2 RNA polymerase III RPC4 DUF2052 PF09747.9 EKX33529.1 - 9.7e-05 22.6 25.7 0.00013 22.1 14.1 2.2 2 0 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) CNDH2_C PF16858.5 EKX33529.1 - 0.001 19.0 5.8 0.001 19.0 5.8 2.1 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term Afi1 PF07792.12 EKX33529.1 - 0.0053 17.2 3.7 0.0053 17.2 3.7 2.3 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking CDC45 PF02724.14 EKX33529.1 - 0.0063 14.9 27.6 0.033 12.5 17.8 2.0 2 0 0 2 2 2 2 CDC45-like protein BSP_II PF05432.11 EKX33529.1 - 0.0065 16.2 22.0 0.0065 16.2 22.0 2.3 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) Connexin PF00029.19 EKX33529.1 - 0.084 12.6 5.4 5.1 6.8 2.9 2.2 2 0 0 2 2 2 0 Connexin RR_TM4-6 PF06459.12 EKX33529.1 - 0.13 12.1 16.1 0.26 11.1 6.4 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.12 EKX33529.1 - 0.15 11.5 40.7 0.032 13.7 26.3 2.1 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.12 EKX33529.1 - 0.24 9.6 34.2 0.03 12.6 23.4 2.1 2 0 0 2 2 2 0 Nop14-like family Mpp10 PF04006.12 EKX33529.1 - 0.25 9.7 37.2 0.1 11.0 24.1 2.1 2 0 0 2 2 2 0 Mpp10 protein CPSF100_C PF13299.6 EKX33529.1 - 0.64 10.2 15.0 1.5 9.0 5.2 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF913 PF06025.12 EKX33529.1 - 0.7 8.8 7.5 0.52 9.2 1.4 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Peroxin-13_N PF04088.13 EKX33529.1 - 0.73 10.1 4.4 5.2 7.3 0.2 2.4 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Vfa1 PF08432.10 EKX33529.1 - 2.6 8.4 21.4 4.4 7.6 10.7 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DNA_pol_phi PF04931.13 EKX33529.1 - 3.3 5.7 44.3 0.03 12.5 32.3 2.1 2 0 0 2 2 2 0 DNA polymerase phi Plasmodium_Vir PF05795.11 EKX33529.1 - 3.4 7.0 10.5 3.5 7.0 4.0 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein PNISR PF15996.5 EKX33529.1 - 3.9 7.7 29.0 0.75 10.0 15.2 2.2 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR FAM60A PF15396.6 EKX33529.1 - 4.6 7.2 8.5 3.6 7.5 1.1 2.1 2 0 0 2 2 2 0 Protein Family FAM60A Nop53 PF07767.11 EKX33529.1 - 6 6.2 32.7 0.81 9.0 19.4 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) MIF4G_like_2 PF09090.11 EKX33529.1 - 6.2 6.2 9.8 0.21 11.1 1.3 2.2 2 0 0 2 2 2 0 MIF4G like CobT PF06213.12 EKX33529.1 - 7.8 5.8 47.8 3 7.2 30.4 2.8 3 0 0 3 3 3 0 Cobalamin biosynthesis protein CobT Dpy-30 PF05186.13 EKX33530.1 - 1.5e-18 66.2 0.3 1.9e-18 65.8 0.3 1.2 1 0 0 1 1 1 1 Dpy-30 motif RIIa PF02197.17 EKX33530.1 - 0.0036 16.9 0.1 0.0072 16.0 0.1 1.6 1 1 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit DUF1336 PF07059.12 EKX33532.1 - 3.6e-42 145.0 0.1 4.2e-42 144.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) MAPEG PF01124.18 EKX33533.1 - 2.6e-05 24.1 0.3 3.7e-05 23.6 0.3 1.3 1 0 0 1 1 1 1 MAPEG family SecG PF03840.14 EKX33533.1 - 0.062 13.4 0.2 0.41 10.8 0.0 2.2 2 0 0 2 2 2 0 Preprotein translocase SecG subunit CREPT PF16566.5 EKX33534.1 - 0.13 12.4 1.3 0.3 11.2 1.3 1.5 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DUF563 PF04577.14 EKX33536.1 - 4.7e-07 30.2 0.6 2.7e-06 27.7 0.6 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Fn3_assoc PF13287.6 EKX33536.1 - 9.5e-06 25.7 0.0 1.6e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Fn3 associated F5_F8_type_C PF00754.25 EKX33536.1 - 0.00043 20.4 0.0 0.00076 19.6 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain CHB_HEX_C_1 PF13290.6 EKX33536.1 - 0.00055 19.9 0.0 0.00095 19.1 0.0 1.3 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain DUF1770 PF08589.10 EKX33536.1 - 0.4 11.7 1.1 1.1 10.3 0.0 2.1 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1770) N2227 PF07942.12 EKX33538.1 - 7.7e-16 58.1 0.0 1.4e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 EKX33538.1 - 0.0017 19.0 0.0 0.0036 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX33538.1 - 0.02 15.5 0.1 0.059 14.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain DUF4746 PF15928.5 EKX33538.1 - 0.12 11.8 3.1 0.17 11.2 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Sarcoglycan_1 PF04790.13 EKX33538.1 - 1 8.7 5.4 1.7 7.9 5.4 1.3 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein Dynein_light PF01221.18 EKX33539.1 - 2.6e-18 66.1 0.0 7.3e-18 64.7 0.0 1.8 1 0 0 1 1 1 1 Dynein light chain type 1 Imm3 PF14425.6 EKX33539.1 - 0.11 12.6 1.6 0.4 10.7 0.2 2.3 2 0 0 2 2 2 0 Immunity protein Imm3 Conotoxin PF02950.17 EKX33541.1 - 9.8 7.3 9.3 1.5 9.9 0.3 3.7 2 1 1 3 3 3 0 Conotoxin AbrB_C PF18277.1 EKX33542.1 - 0.087 12.5 0.1 0.25 11.0 0.1 1.8 1 0 0 1 1 1 0 AbrB C-terminal domain DUF4551 PF15087.6 EKX33542.1 - 2.8 6.7 12.1 2.9 6.6 12.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Hid1 PF12722.7 EKX33542.1 - 7.6 4.5 17.4 7.8 4.5 17.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pkinase_Tyr PF07714.17 EKX33543.1 - 3.4e-58 196.9 0.0 4.2e-58 196.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX33543.1 - 2.3e-28 99.3 0.0 3e-28 98.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EKX33543.1 - 0.15 11.3 0.3 0.4 9.9 0.3 1.7 1 1 0 1 1 1 0 Kinase-like Ephrin_rec_like PF07699.13 EKX33544.1 - 4.2e-16 58.4 79.1 8.1e-05 22.3 8.9 7.5 1 1 7 8 8 8 8 Putative ephrin-receptor like NCD3G PF07562.14 EKX33544.1 - 9.2e-11 41.5 52.3 0.017 15.1 7.3 7.2 3 2 2 7 7 7 6 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX33544.1 - 0.00094 19.5 58.0 0.0064 16.9 1.3 9.0 3 3 4 8 8 8 7 TNFR/NGFR cysteine-rich region VSP PF03302.13 EKX33544.1 - 0.65 8.8 57.8 0.077 11.8 10.1 3.0 1 1 2 3 3 3 0 Giardia variant-specific surface protein TPR_2 PF07719.17 EKX33545.1 - 3.4e-08 33.0 6.8 5.3e-05 23.0 0.3 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX33545.1 - 3.9e-07 30.6 5.5 2.3e-05 24.9 0.9 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX33545.1 - 5.9e-07 29.8 8.3 0.0095 16.7 0.9 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX33545.1 - 8.1e-07 28.6 2.2 0.00044 20.0 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX33545.1 - 1.3e-06 28.1 2.7 0.012 15.8 0.2 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX33545.1 - 2.1e-06 27.9 8.0 0.0024 18.1 0.6 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX33545.1 - 1.6e-05 25.3 1.6 1.6e-05 25.3 1.6 2.5 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX33545.1 - 0.0002 21.5 0.9 0.0037 17.5 0.3 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX33545.1 - 0.00092 19.3 0.7 0.0026 17.9 0.7 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX33545.1 - 0.0019 18.7 2.1 1 10.2 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX33545.1 - 0.0026 17.4 0.1 0.01 15.5 0.1 2.0 1 1 1 2 2 2 1 TPR repeat Nmad5 PF18757.1 EKX33545.1 - 0.0053 17.0 0.1 0.0093 16.2 0.1 1.3 1 0 0 1 1 1 1 Nucleotide modification associated domain 5 TetR_C_31 PF17940.1 EKX33545.1 - 0.05 13.8 0.3 0.35 11.1 0.0 2.4 3 0 0 3 3 2 0 Tetracyclin repressor-like, C-terminal domain TPR_20 PF14561.6 EKX33545.1 - 0.063 13.6 0.1 0.2 12.0 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 EKX33545.1 - 0.17 12.0 4.6 9 6.6 0.4 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX33545.1 - 0.33 10.9 6.4 4.6 7.2 0.8 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EKX33546.1 - 0.00029 20.7 0.0 0.0014 18.6 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX33546.1 - 0.022 14.6 0.0 0.08 12.8 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat RRM_3 PF08777.11 EKX33546.1 - 0.041 13.9 0.0 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif TPR_11 PF13414.6 EKX33546.1 - 0.064 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 TPR repeat TPR_8 PF13181.6 EKX33546.1 - 0.093 13.0 0.0 0.32 11.3 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat RE_XamI PF09572.10 EKX33548.1 - 0.069 12.8 0.0 0.084 12.5 0.0 1.1 1 0 0 1 1 1 0 XamI restriction endonuclease Diphthamide_syn PF01866.17 EKX33549.1 - 2.5e-53 181.5 0.2 8.5e-37 127.2 0.0 2.1 1 1 1 2 2 2 2 Putative diphthamide synthesis protein DUF4623 PF15416.6 EKX33549.1 - 0.091 11.3 0.1 0.14 10.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4623) Tox-ODYAM1 PF15642.6 EKX33550.1 - 0.84 8.5 9.2 1.3 7.9 9.2 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus AAA_23 PF13476.6 EKX33550.1 - 4.6 7.7 11.6 10 6.5 11.6 1.5 1 0 0 1 1 1 0 AAA domain Activator_LAG-3 PF11498.8 EKX33550.1 - 4.9 6.0 18.3 8.9 5.2 18.3 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 SAP PF02037.27 EKX33551.1 - 3.3e-16 58.6 2.5 2.1e-14 52.8 1.1 2.6 2 1 1 3 3 3 1 SAP domain Tho1_MOS11_C PF18592.1 EKX33551.1 - 0.00039 20.2 0.6 0.00085 19.1 0.1 1.9 2 0 0 2 2 2 1 Tho1/MOS11 C-terminal domain FANC_SAP PF18081.1 EKX33551.1 - 0.045 13.9 0.2 0.13 12.5 0.2 1.7 1 0 0 1 1 1 0 Fanconi anemia-associated nuclease SAP domain Packaging_FI PF14000.6 EKX33551.1 - 0.064 13.7 1.7 0.1 13.1 1.3 1.5 1 1 0 1 1 1 0 DNA packaging protein FI MCPVI PF02993.14 EKX33551.1 - 0.11 12.4 3.6 0.16 11.8 3.6 1.2 1 0 0 1 1 1 0 Minor capsid protein VI Apc15p PF05841.11 EKX33551.1 - 0.13 13.1 0.8 0.19 12.5 0.8 1.2 1 0 0 1 1 1 0 Apc15p protein DUF3275 PF11679.8 EKX33551.1 - 0.47 10.4 5.6 0.57 10.1 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) DUF3807 PF12720.7 EKX33551.1 - 1.7 8.9 6.4 2.3 8.5 6.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Mucin PF01456.17 EKX33551.1 - 2.8 7.9 13.1 3.8 7.5 13.1 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Presenilin PF01080.17 EKX33551.1 - 3.8 6.2 5.0 4.2 6.0 5.0 1.0 1 0 0 1 1 1 0 Presenilin Ank_5 PF13857.6 EKX33554.1 - 5.6e-16 58.4 3.1 8.5e-09 35.5 0.3 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX33554.1 - 8.7e-16 58.1 3.8 3.6e-11 43.3 0.4 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX33554.1 - 3e-14 53.4 0.1 6.6e-14 52.3 0.2 1.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX33554.1 - 5e-13 48.0 0.8 7.5e-05 22.8 0.2 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EKX33554.1 - 1.6e-12 47.2 0.6 3.1e-05 24.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat DUF5535 PF17687.1 EKX33554.1 - 0.17 12.1 0.0 0.67 10.2 0.0 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5535) Alpha_kinase PF02816.18 EKX33555.1 - 1e-57 195.2 0.0 2.4e-57 194.1 0.0 1.6 1 0 0 1 1 1 1 Alpha-kinase family EF-hand_4 PF12763.7 EKX33555.1 - 0.0033 17.3 0.0 0.0094 15.9 0.0 1.7 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand RNase_3_N PF18497.1 EKX33555.1 - 0.011 16.0 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease III N-terminal domain Exonuc_VII_L PF02601.15 EKX33555.1 - 0.55 9.8 9.9 0.08 12.5 5.3 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit WD40 PF00400.32 EKX33556.1 - 0.064 14.2 0.4 11 7.0 0.0 2.9 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF3446 PF11928.8 EKX33556.1 - 1.3 9.4 16.9 0.24 11.7 11.8 2.2 2 0 0 2 2 2 0 Early growth response N-terminal domain PP2C PF00481.21 EKX33558.1 - 2e-33 116.2 0.0 2.4e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Ribosomal_S2 PF00318.20 EKX33558.1 - 0.18 11.0 0.0 0.24 10.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S2 DUF1296 PF06972.11 EKX33558.1 - 0.26 11.4 0.5 1.4 9.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) ATG16 PF08614.11 EKX33559.1 - 4.8e-18 66.1 16.5 4.8e-18 66.1 16.5 2.3 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) WD40 PF00400.32 EKX33559.1 - 1.1e-09 38.7 0.0 1.4e-05 25.7 0.0 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat RAP80_UIM PF18282.1 EKX33559.1 - 0.034 13.9 2.7 0.1 12.4 0.8 2.8 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif ANAPC4_WD40 PF12894.7 EKX33559.1 - 0.06 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Flu_NS2 PF00601.19 EKX33559.1 - 0.2 12.0 0.1 0.2 12.0 0.1 2.6 3 0 0 3 3 3 0 Influenza non-structural protein (NS2) Mod_r PF07200.13 EKX33559.1 - 0.25 11.5 23.9 0.86 9.7 0.8 3.7 3 1 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF3573 PF12097.8 EKX33559.1 - 1.9 7.2 3.8 1.6 7.5 1.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) APG6_N PF17675.1 EKX33559.1 - 2.2 8.8 37.5 0.21 12.1 8.3 4.0 2 2 2 4 4 4 0 Apg6 coiled-coil region Transformer PF06495.11 EKX33559.1 - 2.8 8.0 11.3 0.21 11.7 5.9 1.8 2 0 0 2 2 2 0 Fruit fly transformer protein SlyX PF04102.12 EKX33559.1 - 4 8.1 17.2 0.85 10.3 4.5 4.2 3 1 0 3 3 3 0 SlyX HAP1_N PF04849.13 EKX33559.1 - 9.2 5.4 31.9 0.44 9.7 9.4 3.4 3 1 2 5 5 5 0 HAP1 N-terminal conserved region Collagen PF01391.18 EKX33560.1 - 7.8e-08 32.0 27.7 7.8e-08 32.0 27.7 2.5 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) VWD PF00094.25 EKX33560.1 - 0.00021 21.6 0.1 0.00021 21.6 0.1 2.3 3 0 0 3 3 3 1 von Willebrand factor type D domain Redoxin PF08534.10 EKX33561.1 - 1.6e-23 83.1 0.0 2.1e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EKX33561.1 - 2.9e-09 36.9 0.0 3e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DUF865 PF05906.11 EKX33561.1 - 0.14 12.0 0.0 6.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Herpesvirus-7 repeat of unknown function (DUF865) E1_dh PF00676.20 EKX33562.1 - 1.8e-88 296.4 0.3 2.3e-88 296.0 0.3 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EKX33562.1 - 2.2e-05 23.8 0.0 0.00013 21.3 0.0 1.9 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 EKX33562.1 - 0.00028 20.7 0.1 0.00061 19.6 0.1 1.6 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain MFS_1 PF07690.16 EKX33563.1 - 3.5e-10 39.3 4.3 6e-10 38.6 4.3 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Gp49 PF05973.14 EKX33563.1 - 0.1 12.7 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Phage derived protein Gp49-like (DUF891) Pkinase_Tyr PF07714.17 EKX33564.1 - 9.5e-61 205.3 0.0 1.1e-60 205.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX33564.1 - 2.5e-29 102.5 0.0 3.2e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain zf-C3HC4_3 PF13920.6 EKX33564.1 - 2.2e-10 40.3 13.1 3.8e-10 39.5 13.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX33564.1 - 7.1e-09 35.4 10.0 7.1e-09 35.4 10.0 2.2 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EKX33564.1 - 0.17 12.3 14.3 0.4 11.1 14.3 1.6 1 0 0 1 1 1 0 Ring finger domain UCH PF00443.29 EKX33566.1 - 2.1e-37 129.0 0.0 6.5e-37 127.4 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EKX33566.1 - 4.4e-07 29.8 0.2 0.00041 20.1 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase HOIP-UBA PF16678.5 EKX33566.1 - 0.001 19.1 2.5 0.41 10.6 0.2 3.8 5 0 0 5 5 5 2 HOIP UBA domain pair UIM PF02809.20 EKX33566.1 - 0.0022 17.8 13.2 0.13 12.2 1.6 3.0 2 0 0 2 2 2 2 Ubiquitin interaction motif UBA_4 PF14555.6 EKX33566.1 - 0.0091 15.8 0.1 0.099 12.5 0.1 2.6 3 0 0 3 3 3 1 UBA-like domain UBA PF00627.31 EKX33566.1 - 0.045 13.7 2.0 0.22 11.5 2.0 2.2 1 1 0 1 1 1 0 UBA/TS-N domain Endostatin PF06482.11 EKX33567.1 - 0.0056 16.2 21.2 0.0073 15.8 21.2 1.2 1 0 0 1 1 1 1 Collagenase NC10 and Endostatin NHL PF01436.21 EKX33567.1 - 0.0083 16.1 0.0 0.052 13.6 0.0 2.4 2 0 0 2 2 2 1 NHL repeat SID-1_RNA_chan PF13965.6 EKX33567.1 - 0.016 13.6 8.7 0.021 13.3 8.7 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Borrelia_P83 PF05262.11 EKX33567.1 - 0.062 11.8 26.5 0.081 11.4 26.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein AAA_11 PF13086.6 EKX33567.1 - 2.1 8.1 33.1 3 7.6 33.1 1.2 1 0 0 1 1 1 0 AAA domain Velvet PF11754.8 EKX33567.1 - 4.8 7.1 30.4 8.9 6.2 30.4 1.5 1 0 0 1 1 1 0 Velvet factor LMBR1 PF04791.16 EKX33567.1 - 5.7 5.7 21.1 2.3 7.0 18.7 1.5 2 0 0 2 2 2 0 LMBR1-like membrane protein PTPRCAP PF15713.5 EKX33567.1 - 8.6 6.6 40.4 13 6.0 40.4 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated TMEM154 PF15102.6 EKX33568.1 - 0.076 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family SRF-TF PF00319.18 EKX33569.1 - 3.3e-15 55.3 0.2 4.4e-15 54.9 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Rad17 PF03215.15 EKX33569.1 - 0.04 13.8 0.1 0.044 13.7 0.1 1.1 1 0 0 1 1 1 0 Rad17 P-loop domain DUF4911 PF16256.5 EKX33569.1 - 0.062 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) Acetyltransf_10 PF13673.7 EKX33571.1 - 2.3e-12 47.0 0.0 6.9e-12 45.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EKX33571.1 - 4.1e-12 46.3 0.0 6.6e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EKX33571.1 - 2.3e-09 37.5 0.0 4.6e-09 36.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family PanZ PF12568.8 EKX33571.1 - 8.2e-05 22.3 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 EKX33571.1 - 0.0011 19.0 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 EKX33571.1 - 0.0049 16.8 0.3 0.039 13.9 0.3 2.1 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EKX33571.1 - 0.017 15.2 0.2 1.3 9.2 0.0 2.5 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EKX33571.1 - 0.045 14.4 0.0 0.066 13.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EKX33571.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.4 1 1 0 1 1 1 0 Putative acetyl-transferase DAGK_cat PF00781.24 EKX33572.1 - 2.2e-22 79.0 0.0 3.8e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF4081 PF13312.6 EKX33572.1 - 0.076 13.2 0.6 0.24 11.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4081) Mg-por_mtran_C PF07109.11 EKX33573.1 - 3.1e-32 110.8 0.0 6.2e-32 109.8 0.0 1.5 1 0 0 1 1 1 1 Magnesium-protoporphyrin IX methyltransferase C-terminus Methyltransf_25 PF13649.6 EKX33573.1 - 2.6e-12 47.3 0.4 5.8e-12 46.2 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX33573.1 - 1.5e-09 38.5 0.1 4e-09 37.1 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX33573.1 - 8e-09 35.5 0.1 1.8e-08 34.4 0.1 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX33573.1 - 1.6e-08 35.0 0.2 4e-08 33.8 0.1 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX33573.1 - 1.3e-07 31.6 0.0 2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EKX33573.1 - 3.2e-07 29.9 0.0 6.4e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EKX33573.1 - 3.8e-05 23.1 0.1 5.5e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EKX33573.1 - 0.00061 19.8 0.0 0.00095 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EKX33573.1 - 0.0037 16.8 0.2 0.0056 16.2 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EKX33573.1 - 0.0047 16.4 0.3 0.0073 15.7 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 EKX33573.1 - 0.023 14.4 1.4 0.15 11.7 1.1 2.2 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 Mur_ligase PF01225.25 EKX33573.1 - 0.025 14.9 0.3 0.07 13.5 0.2 1.7 2 0 0 2 2 1 0 Mur ligase family, catalytic domain Methyltransf_18 PF12847.7 EKX33573.1 - 0.029 14.3 0.1 0.071 13.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 EKX33573.1 - 0.11 11.5 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase DELLA PF12041.8 EKX33573.1 - 0.13 12.2 0.0 4.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal AdoMet_MTase PF07757.13 EKX33573.1 - 0.14 12.5 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase PepSY_2 PF13670.6 EKX33573.1 - 0.46 10.5 2.5 3.4 7.7 0.0 2.9 2 1 0 2 2 2 0 Peptidase propeptide and YPEB domain BSD PF03909.17 EKX33574.1 - 2.1e-08 34.0 1.3 4.8e-08 32.9 0.4 2.0 2 0 0 2 2 2 1 BSD domain PH_TFIIH PF08567.11 EKX33574.1 - 1.8e-05 25.0 0.0 4.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Pkinase PF00069.25 EKX33575.1 - 2e-19 70.0 0.0 1.3e-18 67.4 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain LRR_8 PF13855.6 EKX33575.1 - 6.6e-17 61.0 20.9 1.1e-07 31.5 0.8 4.5 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EKX33575.1 - 1.1e-12 48.0 24.3 9.9e-05 22.6 1.7 4.8 2 2 3 5 5 5 5 Leucine Rich repeats (2 copies) Pkinase_Tyr PF07714.17 EKX33575.1 - 1.2e-11 44.4 0.0 1.4e-10 40.9 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EKX33575.1 - 3e-06 26.7 0.0 4.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX33575.1 - 0.0079 16.1 0.0 0.024 14.5 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EKX33575.1 - 0.0091 15.6 0.0 0.57 9.8 0.0 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 LRR_9 PF14580.6 EKX33575.1 - 0.024 14.1 6.0 0.12 11.9 3.8 2.4 1 1 2 3 3 3 0 Leucine-rich repeat LRR_1 PF00560.33 EKX33575.1 - 0.041 14.4 23.9 2.2 9.1 0.0 6.8 7 0 0 7 7 7 0 Leucine Rich Repeat ANXA2R PF15721.5 EKX33575.1 - 0.069 13.7 0.2 0.12 12.9 0.2 1.3 1 0 0 1 1 1 0 Annexin-2 receptor RIO1 PF01163.22 EKX33575.1 - 0.15 11.6 0.7 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 RIO1 family MatE PF01554.18 EKX33576.1 - 3.6e-40 137.2 28.6 5e-24 84.8 4.5 2.9 2 1 1 3 3 3 2 MatE Polysacc_synt_C PF14667.6 EKX33576.1 - 3.5e-05 23.9 9.8 3.5e-05 23.9 9.8 3.3 2 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain PAP_fibrillin PF04755.12 EKX33577.1 - 0.0018 18.3 0.0 0.0064 16.4 0.0 1.9 1 1 0 1 1 1 1 PAP_fibrillin Rad60-SLD PF11976.8 EKX33579.1 - 2.2e-09 37.0 0.1 5.6e-09 35.7 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EKX33579.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family BORG_CEP PF14957.6 EKX33579.1 - 0.08 14.1 3.3 0.18 12.9 3.3 1.6 1 0 0 1 1 1 0 Cdc42 effector YebO PF13974.6 EKX33579.1 - 0.2 11.8 0.5 0.49 10.5 0.0 1.9 2 0 0 2 2 2 0 YebO-like protein Band_7 PF01145.25 EKX33581.1 - 1.3e-30 106.7 0.0 1.8e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 EKX33581.1 - 0.086 12.5 0.1 0.17 11.5 0.0 1.5 2 0 0 2 2 2 0 SPFH domain-Band 7 family HA2 PF04408.23 EKX33582.1 - 4.5e-17 62.3 0.0 8.6e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EKX33582.1 - 4.7e-15 55.9 0.0 1.3e-14 54.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EKX33582.1 - 4.6e-10 39.6 0.0 8.7e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 EKX33582.1 - 9.1e-09 35.6 0.0 2.2e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 EKX33582.1 - 0.00011 22.6 0.0 0.00025 21.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EKX33582.1 - 0.00054 19.5 0.0 0.001 18.5 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_30 PF13604.6 EKX33582.1 - 0.0061 16.3 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EKX33582.1 - 0.0076 16.5 0.2 0.03 14.6 0.2 2.0 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EKX33582.1 - 0.043 14.3 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 EKX33582.1 - 0.06 13.9 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EKX33582.1 - 0.14 11.9 0.3 3.4 7.4 0.2 2.2 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.6 EKX33582.1 - 0.15 11.8 0.0 0.4 10.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PDZ_6 PF17820.1 EKX33583.1 - 1.3e-10 40.9 0.1 3.2e-10 39.7 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX33583.1 - 4.9e-07 30.0 0.1 9.4e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 PDZ domain SH2 PF00017.24 EKX33583.1 - 1.8e-05 24.8 0.0 6e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 SH2 domain PDZ PF00595.24 EKX33583.1 - 2.3e-05 24.6 0.1 4.7e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX33583.1 - 0.0048 16.8 0.1 0.019 14.9 0.0 2.1 2 0 0 2 2 2 1 Tricorn protease PDZ domain XPB_DRD PF18458.1 EKX33583.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Xeroderma pigmentosum group B helicase damage recognition domain GlutR_dimer PF00745.20 EKX33584.1 - 0.058 13.8 2.0 0.16 12.5 2.0 1.7 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain Syntaxin PF00804.25 EKX33584.1 - 0.1 12.3 6.8 0.14 11.9 5.8 1.8 1 1 0 1 1 1 0 Syntaxin DUF2362 PF10154.9 EKX33584.1 - 0.96 8.3 15.4 0.19 10.7 11.2 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2362) EF-hand_1 PF00036.32 EKX33585.1 - 0.00046 19.6 0.0 0.0011 18.3 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EKX33585.1 - 0.0079 16.1 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 EKX33585.1 - 0.019 15.4 0.0 0.04 14.4 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair Upf2 PF04050.14 EKX33585.1 - 2.8 8.7 8.2 0.41 11.4 2.4 2.5 3 0 0 3 3 3 0 Up-frameshift suppressor 2 DUF2800 PF10926.8 EKX33586.1 - 0.16 11.2 0.1 0.16 11.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) Pkinase PF00069.25 EKX33588.1 - 5.6e-33 114.4 0.0 6e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX33588.1 - 4.5e-23 81.8 0.0 4.7e-23 81.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX33588.1 - 3.6e-05 23.2 0.0 4.2e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EKX33588.1 - 0.00049 19.0 0.0 0.00051 18.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EKX33588.1 - 0.05 12.9 0.0 0.064 12.6 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 EKX33588.1 - 0.071 12.1 0.0 0.09 11.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase FTA2 PF13095.6 EKX33588.1 - 0.17 11.5 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 zf-C3HC4_3 PF13920.6 EKX33589.1 - 2.7e-10 40.0 10.9 3.7e-10 39.5 10.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX33589.1 - 0.00061 19.6 12.1 0.0011 18.8 12.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EKX33589.1 - 0.13 12.6 12.0 0.25 11.7 12.0 1.5 1 0 0 1 1 1 0 Ring finger domain ASH PF15780.5 EKX33590.1 - 9.1e-29 99.6 10.9 0.0087 16.2 0.0 14.0 14 1 2 16 16 16 7 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 EKX33590.1 - 6.1e-11 42.4 0.2 4.3e-07 30.0 0.0 5.1 5 0 0 5 5 5 1 Flagellar-associated PapD-like Motile_Sperm PF00635.26 EKX33590.1 - 1.2e-09 37.9 2.2 0.51 10.2 0.0 7.0 7 0 0 7 7 7 3 MSP (Major sperm protein) domain DUF1573 PF07610.11 EKX33590.1 - 2.4e-06 27.5 0.6 0.0054 16.7 0.0 6.0 6 0 0 6 6 6 1 Protein of unknown function (DUF1573) Transglut_C PF00927.22 EKX33590.1 - 8.9e-06 25.8 0.5 0.0079 16.3 0.0 4.6 3 1 0 3 3 3 1 Transglutaminase family, C-terminal ig like domain CH PF00307.31 EKX33590.1 - 0.00017 21.8 0.0 0.00036 20.7 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain TMEM131_like PF12371.8 EKX33590.1 - 0.0038 17.4 9.6 3.4 8.0 0.0 6.8 7 0 0 7 7 7 1 Transmembrane protein 131-like DUF2457 PF10446.9 EKX33590.1 - 0.31 10.1 18.0 0.52 9.4 18.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 EKX33590.1 - 0.49 9.7 16.5 0.86 8.9 16.5 1.3 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 EKX33590.1 - 3.6 5.7 8.3 6 5.0 8.3 1.2 1 0 0 1 1 1 0 Nop14-like family Proteasom_Rpn13 PF04683.13 EKX33591.1 - 5.2e-26 91.0 0.0 5.8e-26 90.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RXLR PF16810.5 EKX33592.1 - 0.0081 16.6 0.2 0.014 15.9 0.2 1.4 1 0 0 1 1 1 1 RXLR phytopathogen effector protein, Avirulence activity LapA_dom PF06305.11 EKX33592.1 - 0.19 11.6 0.9 0.53 10.1 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain EF-hand_7 PF13499.6 EKX33593.1 - 0.0017 18.8 0.1 0.0058 17.1 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX33593.1 - 0.0023 17.7 0.3 0.01 15.7 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EKX33593.1 - 0.011 15.2 0.1 0.047 13.3 0.0 2.2 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.6 EKX33593.1 - 0.047 13.2 0.9 0.091 12.3 0.1 1.9 2 0 0 2 2 2 0 EF hand SET PF00856.28 EKX33594.1 - 9.4e-07 29.4 0.6 3.9e-06 27.4 0.6 1.8 1 1 0 1 1 1 1 SET domain WD40 PF00400.32 EKX33595.1 - 4.4e-13 49.5 11.0 2.6e-07 31.2 0.2 7.2 6 2 1 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX33595.1 - 2.7e-10 40.4 0.2 0.07 13.4 0.0 5.7 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 EKX33595.1 - 5.1e-06 26.4 7.7 0.4 10.5 0.0 5.0 4 1 0 5 5 5 2 Region in Clathrin and VPS PPR PF01535.20 EKX33595.1 - 0.00084 19.4 1.5 2.6 8.5 0.0 4.9 4 1 1 5 5 5 1 PPR repeat Coatomer_WDAD PF04053.14 EKX33595.1 - 0.0017 17.5 10.4 0.36 9.8 0.2 5.6 5 1 1 6 6 6 2 Coatomer WD associated region TPR_14 PF13428.6 EKX33595.1 - 0.014 16.1 1.8 19 6.4 0.2 5.0 5 1 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX33595.1 - 0.053 13.7 0.6 6.7 7.0 0.0 3.6 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EKX33595.1 - 0.52 10.6 3.5 17 5.8 0.0 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat PPR_2 PF13041.6 EKX33595.1 - 0.67 10.2 4.9 15 5.9 0.0 4.4 5 0 0 5 5 5 0 PPR repeat family TPR_2 PF07719.17 EKX33595.1 - 7.4 7.0 7.4 15 6.0 0.5 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat zf-C4 PF00105.18 EKX33596.1 - 0.037 14.5 0.9 0.091 13.2 0.9 1.7 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) DUF924 PF06041.11 EKX33597.1 - 1.4e-23 84.0 3.3 1.5e-23 83.9 3.3 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Pro-NT_NN PF07421.11 EKX33597.1 - 0.007 16.6 0.6 0.01 16.1 0.6 1.3 1 1 0 1 1 1 1 Neurotensin/neuromedin N precursor LIME1 PF15332.6 EKX33597.1 - 0.0081 15.8 0.1 0.011 15.3 0.1 1.2 1 0 0 1 1 1 1 Lck-interacting transmembrane adapter 1 MFS_3 PF05977.13 EKX33597.1 - 0.28 9.5 0.2 0.31 9.4 0.2 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector ATP_bind_3 PF01171.20 EKX33598.1 - 1.7e-11 44.2 0.0 2.1e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 PP-loop family QueC PF06508.13 EKX33598.1 - 0.051 13.1 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC Abp2 PF09441.10 EKX33598.1 - 0.13 12.4 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 ARS binding protein 2 SGL PF08450.12 EKX33599.1 - 5.5e-63 212.8 0.0 6.7e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region PQQ_3 PF13570.6 EKX33599.1 - 0.088 13.3 0.1 4.3 7.9 0.0 2.9 3 0 0 3 3 3 0 PQQ-like domain Sugar_tr PF00083.24 EKX33600.1 - 9.6e-30 103.8 11.8 9.6e-30 103.8 11.8 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 EKX33600.1 - 1.9e-22 79.7 28.4 6.2e-22 78.0 25.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CbtB PF09489.10 EKX33600.1 - 0.032 14.3 0.3 2.2 8.5 0.0 3.0 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) TPR_16 PF13432.6 EKX33602.1 - 7.6e-08 32.9 4.5 0.0018 18.9 0.2 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX33602.1 - 0.007 16.0 0.2 2.8 7.7 0.0 2.8 2 1 1 3 3 3 2 TPR repeat TPR_14 PF13428.6 EKX33602.1 - 0.038 14.8 1.2 9.2 7.4 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EKX33602.1 - 0.17 12.1 4.9 5.8 7.3 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 EKX33602.1 - 1.4 9.5 5.0 11 6.7 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat GMP_PDE_delta PF05351.11 EKX33604.1 - 8.2e-61 204.7 0.3 9.5e-61 204.5 0.3 1.0 1 0 0 1 1 1 1 GMP-PDE, delta subunit EH_Signature PF15611.6 EKX33605.1 - 0.0028 17.2 0.5 0.0055 16.2 0.5 1.4 1 0 0 1 1 1 1 EH_Signature domain SET PF00856.28 EKX33605.1 - 0.0059 17.0 0.0 0.016 15.6 0.0 2.0 1 1 0 1 1 1 1 SET domain DUF2721 PF11026.8 EKX33605.1 - 0.13 12.2 0.1 0.35 10.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) SAM_1 PF00536.30 EKX33606.1 - 1.9e-07 31.4 0.5 8.9e-07 29.3 0.1 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) HEAT_2 PF13646.6 EKX33606.1 - 0.00033 21.0 3.8 0.9 10.0 0.0 4.5 6 0 0 6 6 6 2 HEAT repeats MIB_HERC2 PF06701.13 EKX33606.1 - 0.0013 18.9 0.1 0.008 16.4 0.1 2.3 2 0 0 2 2 2 1 Mib_herc2 HEAT PF02985.22 EKX33606.1 - 0.021 15.1 0.1 3.8 8.0 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat PDZ_6 PF17820.1 EKX33606.1 - 0.1 12.4 0.0 0.43 10.5 0.0 2.1 1 0 0 1 1 1 0 PDZ domain Trypsin PF00089.26 EKX33607.1 - 1.1e-29 103.8 0.0 1.4e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 Trypsin AMP-binding PF00501.28 EKX33608.1 - 8.4e-91 304.7 0.0 1e-90 304.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EKX33608.1 - 1.1e-20 74.4 0.1 2.1e-20 73.5 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ShK PF01549.24 EKX33609.1 - 0.077 13.6 0.3 0.2 12.2 0.1 1.8 2 0 0 2 2 2 0 ShK domain-like ORC_WH_C PF18137.1 EKX33609.1 - 0.21 11.7 0.0 0.25 11.4 0.0 1.0 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal LRR_8 PF13855.6 EKX33610.1 - 3.8e-29 100.2 22.9 2.7e-13 49.5 4.4 4.0 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EKX33610.1 - 1e-17 63.9 12.8 1.3e-07 31.8 1.0 3.9 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX33610.1 - 2.3e-09 37.3 0.0 2e-05 24.5 0.0 1.9 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 EKX33610.1 - 1.7e-06 27.6 0.3 0.001 18.6 0.2 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 EKX33610.1 - 0.0011 19.2 16.7 0.99 10.2 0.1 5.8 6 0 0 6 6 6 3 Leucine Rich Repeat COX_ARM PF06481.14 EKX33610.1 - 0.21 11.5 0.2 9.5 6.2 0.0 3.4 4 0 0 4 4 4 0 COX Aromatic Rich Motif Glyco_transf_29 PF00777.18 EKX33611.1 - 2e-27 96.3 0.0 3.5e-25 88.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) Glyco_transf_25 PF01755.17 EKX33612.1 - 6.9e-07 29.3 0.0 1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glyco_transf_18 PF15024.6 EKX33613.1 - 5.1e-13 48.5 0.1 2.1e-09 36.5 0.0 2.7 2 1 1 3 3 3 2 Glycosyltransferase family 18 RNase_PH PF01138.21 EKX33614.1 - 1.9e-06 28.4 0.1 1.9e-06 28.4 0.1 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EKX33614.1 - 1.9e-05 24.6 0.0 4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Spectrin_like PF18373.1 EKX33615.1 - 0.15 12.2 0.8 0.32 11.1 0.0 1.9 2 0 0 2 2 2 0 Spectrin like domain MFS_1 PF07690.16 EKX33616.1 - 3.9e-25 88.5 25.5 4.5e-25 88.3 25.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EKX33616.1 - 2.2e-09 36.7 1.9 2.2e-09 36.7 1.9 1.8 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 EKX33616.1 - 1.9e-06 27.0 14.5 2.4e-05 23.4 14.5 2.0 1 1 0 1 1 1 1 MFS_1 like family DEAD PF00270.29 EKX33617.1 - 2.3e-22 79.6 0.1 4.1e-22 78.8 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX33617.1 - 3.6e-13 49.8 0.1 1.3e-11 44.8 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ANF_receptor PF01094.28 EKX33617.1 - 0.0019 17.4 0.1 0.0031 16.7 0.1 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region ResIII PF04851.15 EKX33617.1 - 0.0025 17.8 0.0 0.0057 16.7 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Peripla_BP_4 PF13407.6 EKX33617.1 - 0.012 15.2 0.1 0.017 14.7 0.1 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain Rhodanese PF00581.20 EKX33617.1 - 0.023 15.2 0.0 0.72 10.4 0.0 2.4 2 0 0 2 2 2 0 Rhodanese-like domain Methyltransf_17 PF12692.7 EKX33617.1 - 0.089 12.8 0.0 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 S-adenosyl-L-methionine methyltransferase RWP-RK PF02042.15 EKX33618.1 - 6.1e-16 58.1 0.0 1e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX33618.1 - 0.006 16.3 0.1 0.031 14.0 0.0 2.1 1 1 1 2 2 2 1 Bacterial regulatory protein, Fis family Sigma70_r4_2 PF08281.12 EKX33618.1 - 0.078 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_17 PF12728.7 EKX33618.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Glyco_transf_90 PF05686.12 EKX33620.1 - 3.8e-47 161.1 0.2 4.6e-47 160.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Filamin PF00630.19 EKX33620.1 - 2.4e-05 25.1 0.1 7.3e-05 23.5 0.0 1.9 1 1 1 2 2 2 1 Filamin/ABP280 repeat LCM PF04072.14 EKX33621.1 - 1.3e-22 80.6 0.0 5.7e-22 78.6 0.0 1.8 1 1 1 2 2 2 1 Leucine carboxyl methyltransferase Queuosine_synth PF02547.15 EKX33622.1 - 1.2e-84 284.3 0.0 3.8e-84 282.6 0.0 1.8 1 1 0 1 1 1 1 Queuosine biosynthesis protein Vut_1 PF02592.15 EKX33622.1 - 8.9e-31 107.2 4.7 2.9e-22 79.6 1.6 2.3 1 1 1 2 2 2 2 Putative vitamin uptake transporter MatE PF01554.18 EKX33622.1 - 0.27 10.9 2.6 0.54 9.9 2.6 1.4 1 0 0 1 1 1 0 MatE Spt20 PF12090.8 EKX33622.1 - 0.39 10.3 3.3 0.77 9.3 3.3 1.4 1 0 0 1 1 1 0 Spt20 family MtrF PF09472.10 EKX33623.1 - 1.3 8.5 3.7 2.5 7.5 3.7 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) AAA_16 PF13191.6 EKX33624.1 - 3e-10 40.8 0.1 1.4e-09 38.6 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EKX33624.1 - 7.1e-06 26.3 0.1 1.6e-05 25.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EKX33624.1 - 0.016 14.7 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 EKX33624.1 - 0.03 14.3 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 EKX33624.1 - 0.032 13.5 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) C8 PF08742.11 EKX33624.1 - 0.069 13.6 0.8 0.11 12.9 0.8 1.3 1 0 0 1 1 1 0 C8 domain CENP-F_leu_zip PF10473.9 EKX33627.1 - 0.013 15.5 4.1 0.021 14.9 4.1 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TBCC_N PF16752.5 EKX33627.1 - 0.014 15.8 0.4 0.023 15.2 0.4 1.5 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain Lzipper-MIP1 PF14389.6 EKX33627.1 - 0.026 14.8 1.5 0.042 14.2 1.0 1.7 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DASH_Duo1 PF08651.10 EKX33627.1 - 0.061 13.1 0.3 0.12 12.2 0.3 1.5 1 0 0 1 1 1 0 DASH complex subunit Duo1 Wbp11 PF09429.10 EKX33627.1 - 0.14 12.5 1.9 0.32 11.4 1.7 1.6 2 0 0 2 2 2 0 WW domain binding protein 11 DcpS_C PF11969.8 EKX33629.1 - 0.00034 21.1 0.2 0.00034 21.1 0.2 1.8 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DUF2205 PF10224.9 EKX33629.1 - 0.75 9.8 3.1 5.6 7.0 0.2 2.5 1 1 1 2 2 2 0 Short coiled-coil protein AAA_11 PF13086.6 EKX33630.1 - 1.6e-13 51.0 0.0 2.4e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EKX33630.1 - 3.3e-10 40.0 0.0 0.00018 21.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EKX33630.1 - 3.8e-08 33.8 0.2 1.8e-07 31.6 0.2 2.0 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EKX33630.1 - 1.7e-05 24.7 0.2 0.0066 16.2 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 EKX33630.1 - 0.005 16.5 0.1 0.011 15.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EKX33630.1 - 0.025 15.0 0.0 0.33 11.4 0.0 2.6 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 EKX33630.1 - 0.072 12.3 0.0 0.97 8.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EKX33630.1 - 0.1 12.9 0.0 8.5 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Helicase_RecD PF05127.14 EKX33630.1 - 0.11 12.3 0.0 8 6.3 0.0 2.2 2 0 0 2 2 2 0 Helicase NTPase_1 PF03266.15 EKX33630.1 - 0.17 11.8 0.1 13 5.6 0.0 2.4 2 0 0 2 2 2 0 NTPase ApoO PF09769.9 EKX33630.1 - 0.18 11.8 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein O MeaB PF03308.16 EKX33630.1 - 0.2 10.6 0.0 0.35 9.8 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Psu PF07455.11 EKX33631.1 - 0.066 12.8 0.1 0.18 11.4 0.1 1.7 1 0 0 1 1 1 0 Phage polarity suppression protein (Psu) CDC45 PF02724.14 EKX33631.1 - 1.9 6.7 7.9 2.9 6.1 7.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Ephrin_rec_like PF07699.13 EKX33633.1 - 0.00033 20.4 5.8 0.00033 20.4 5.8 3.9 4 0 0 4 4 4 3 Putative ephrin-receptor like HA1 PF18239.1 EKX33633.1 - 0.024 14.5 0.0 0.75 9.7 0.0 2.7 3 0 0 3 3 3 0 Hemagglutinin I Phage_holin_3_7 PF05449.11 EKX33634.1 - 0.05 13.6 0.0 0.05 13.6 0.0 3.2 2 1 1 3 3 3 0 Putative 3TM holin, Phage_holin_3 Nodulin_late PF07127.11 EKX33634.1 - 0.15 12.4 2.1 0.17 12.3 0.1 2.1 2 0 0 2 2 2 0 Late nodulin protein Pox_P21 PF05313.12 EKX33634.1 - 0.6 9.7 14.0 0.14 11.7 1.9 2.1 1 1 1 2 2 2 0 Poxvirus P21 membrane protein DUF2501 PF10696.9 EKX33636.1 - 0.17 12.1 0.1 0.42 10.9 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2501) PIG-S PF10510.9 EKX33637.1 - 0.014 14.3 0.5 0.027 13.3 0.2 1.5 1 1 1 2 2 2 0 Phosphatidylinositol-glycan biosynthesis class S protein DUF641 PF04859.12 EKX33637.1 - 0.22 11.9 2.5 0.5 10.7 2.5 1.6 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) UPF0113_N PF17833.1 EKX33637.1 - 0.41 11.2 2.2 1.7 9.3 0.5 2.5 2 1 0 2 2 2 0 UPF0113 Pre-PUA domain Lipase_3 PF01764.25 EKX33638.1 - 8.8e-06 25.6 0.0 2.4e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Blt1_C PF17183.4 EKX33638.1 - 0.097 12.3 0.1 0.35 10.5 0.1 1.9 1 0 0 1 1 1 0 Get5 carboxyl domain THOC2_N PF16134.5 EKX33641.1 - 0.0012 17.6 0.1 0.0017 17.1 0.1 1.1 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus MCD_N PF17408.2 EKX33641.1 - 0.12 12.6 0.1 0.44 10.7 0.3 1.9 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase N-terminal domain DUF948 PF06103.11 EKX33641.1 - 0.24 11.7 1.1 0.44 10.8 1.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Nup88 PF10168.9 EKX33643.1 - 5.6e-06 24.5 5.2 5.6e-06 24.5 5.2 5.1 4 2 3 7 7 7 1 Nuclear pore component FPP PF05911.11 EKX33643.1 - 0.00012 20.5 22.0 0.00012 20.5 22.0 4.1 1 1 2 4 4 4 2 Filament-like plant protein, long coiled-coil EIF_2_alpha PF07541.12 EKX33643.1 - 0.012 15.7 1.7 0.048 13.8 1.7 2.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit MbeD_MobD PF04899.12 EKX33643.1 - 0.026 14.7 13.8 0.26 11.4 1.4 5.6 4 0 0 4 4 4 0 MbeD/MobD like DUF745 PF05335.13 EKX33643.1 - 0.03 14.1 0.2 0.03 14.1 0.2 8.0 6 3 5 11 11 11 0 Protein of unknown function (DUF745) Syntaxin-6_N PF09177.11 EKX33643.1 - 0.037 14.6 0.3 0.037 14.6 0.3 11.4 5 4 5 11 11 11 0 Syntaxin 6, N-terminal SlyX PF04102.12 EKX33643.1 - 0.14 12.8 0.1 0.14 12.8 0.1 13.2 13 3 2 15 15 15 0 SlyX MtrB PF05440.12 EKX33643.1 - 0.48 10.9 6.3 18 5.8 0.1 4.8 4 0 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF1664 PF07889.12 EKX33643.1 - 0.6 10.1 84.6 0.18 11.8 0.8 13.0 8 5 3 13 13 13 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EKX33643.1 - 2.1 8.4 43.4 1.6 8.7 0.4 9.8 5 4 5 11 11 11 0 Baculovirus polyhedron envelope protein, PEP, C terminus RNA_pol_N PF01194.17 EKX33644.1 - 0.082 13.2 0.6 0.13 12.6 0.6 1.3 1 0 0 1 1 1 0 RNA polymerases N / 8 kDa subunit BUD22 PF09073.10 EKX33645.1 - 3 7.1 11.5 3.5 6.9 11.5 1.1 1 0 0 1 1 1 0 BUD22 Clusterin PF01093.17 EKX33646.1 - 0.029 13.4 1.9 0.048 12.7 1.9 1.2 1 0 0 1 1 1 0 Clusterin BRF1 PF07741.13 EKX33648.1 - 8.7 6.8 12.8 26 5.2 6.9 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Nab2 PF11517.8 EKX33650.1 - 0.015 15.5 0.2 0.033 14.5 0.2 1.5 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) DUF2089 PF09862.9 EKX33650.1 - 0.95 9.5 5.5 0.24 11.4 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) DUF2829 PF11195.8 EKX33651.1 - 0.097 12.9 0.1 0.097 12.9 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2829) Corona_NS1 PF06145.11 EKX33652.1 - 0.21 11.1 3.2 6.6 6.3 0.3 2.5 2 0 0 2 2 2 0 Coronavirus nonstructural protein NS1 SPX PF03105.19 EKX33660.1 - 8.1e-14 52.3 8.9 4.6e-07 30.1 0.4 4.9 2 2 3 5 5 5 3 SPX domain RWP-RK PF02042.15 EKX33660.1 - 0.091 12.8 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 RWP-RK domain Rubredoxin PF00301.20 EKX33660.1 - 0.2 11.7 0.0 0.41 10.7 0.0 1.5 1 0 0 1 1 1 0 Rubredoxin DUF4407 PF14362.6 EKX33660.1 - 0.21 10.9 6.0 2.3 7.5 3.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CCDC92 PF14916.6 EKX33660.1 - 0.21 11.4 9.4 0.2 11.4 0.4 3.6 3 0 0 3 3 3 0 Coiled-coil domain of unknown function CENP-B_dimeris PF09026.10 EKX33660.1 - 0.41 11.1 13.2 0.12 12.8 3.2 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Uds1 PF15456.6 EKX33660.1 - 1.9 8.6 14.6 0.18 12.0 3.4 3.2 3 1 0 3 3 3 0 Up-regulated During Septation DUF4349 PF14257.6 EKX33660.1 - 2.8 7.4 10.3 0.19 11.2 2.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) FAM176 PF14851.6 EKX33660.1 - 4.8 6.8 12.6 13 5.4 7.3 2.5 2 0 0 2 2 2 0 FAM176 family AAA_23 PF13476.6 EKX33660.1 - 8 6.9 10.8 76 3.7 8.2 2.4 2 0 0 2 2 2 0 AAA domain PsbP PF01789.16 EKX33663.1 - 4.1e-23 82.2 1.3 1.9e-22 80.1 0.1 2.0 2 0 0 2 2 2 1 PsbP WW PF00397.26 EKX33663.1 - 0.00031 20.8 2.3 0.00031 20.8 2.3 2.5 3 0 0 3 3 3 1 WW domain NAPRTase_N PF17767.1 EKX33665.1 - 9.3e-38 129.4 0.0 3.6e-37 127.6 0.0 1.9 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase_C PF17956.1 EKX33665.1 - 1.8e-31 108.8 0.0 3.7e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase PF04095.16 EKX33665.1 - 3e-07 30.3 0.0 0.003 17.2 0.0 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family Cwf_Cwc_15 PF04889.12 EKX33666.1 - 0.059 13.1 25.3 0.064 13.0 25.3 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 EKX33666.1 - 0.1 12.8 34.2 0.11 12.7 34.2 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FAM60A PF15396.6 EKX33666.1 - 0.56 10.2 8.7 0.61 10.1 8.7 1.0 1 0 0 1 1 1 0 Protein Family FAM60A PPP4R2 PF09184.11 EKX33666.1 - 1.2 8.7 29.6 1.3 8.6 29.6 1.0 1 0 0 1 1 1 0 PPP4R2 CDC27 PF09507.10 EKX33666.1 - 2.5 7.4 21.6 3.2 7.0 21.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CSRNP_N PF16019.5 EKX33666.1 - 3.8 7.4 10.5 4.1 7.2 10.5 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus LAP1C PF05609.12 EKX33666.1 - 3.8 6.5 14.9 4.2 6.3 14.9 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) NPR3 PF03666.13 EKX33666.1 - 4.5 5.9 16.5 4.8 5.9 16.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TFIIA PF03153.13 EKX33666.1 - 5 7.0 21.6 5.6 6.8 21.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Vfa1 PF08432.10 EKX33666.1 - 5.4 7.3 20.9 5.9 7.2 20.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BUD22 PF09073.10 EKX33666.1 - 6.6 6.0 30.7 7.3 5.8 30.7 1.0 1 0 0 1 1 1 0 BUD22 Nop53 PF07767.11 EKX33666.1 - 7.8 5.8 30.6 8.3 5.7 30.6 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) MORN PF02493.20 EKX33667.1 - 1.5e-15 56.1 13.2 5.4e-05 22.8 0.6 4.4 3 1 1 4 4 4 4 MORN repeat DUF3760 PF12586.8 EKX33668.1 - 0.16 12.2 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) RWP-RK PF02042.15 EKX33670.1 - 3.6e-12 46.1 0.1 6.3e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_24 PF13412.6 EKX33670.1 - 0.016 14.7 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.12 EKX33670.1 - 0.018 14.7 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Cobalamin_bind PF01122.19 EKX33670.1 - 0.019 13.9 0.1 0.02 13.8 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic cobalamin-binding protein HTH_6 PF01418.17 EKX33670.1 - 0.035 14.1 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family RWP-RK PF02042.15 EKX33671.1 - 1.5e-12 47.3 0.0 2.8e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain HTH_24 PF13412.6 EKX33671.1 - 0.016 14.8 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.12 EKX33671.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_6 PF01418.17 EKX33671.1 - 0.029 14.3 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Cobalamin_bind PF01122.19 EKX33671.1 - 0.038 12.9 0.1 0.044 12.7 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic cobalamin-binding protein RWP-RK PF02042.15 EKX33672.1 - 3.8e-12 46.0 0.0 5.9e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_24 PF13412.6 EKX33672.1 - 0.031 13.8 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.12 EKX33672.1 - 0.034 13.8 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_6 PF01418.17 EKX33672.1 - 0.07 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Methyltransf_15 PF09445.10 EKX33673.1 - 1.2e-40 138.8 0.0 1.7e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 EKX33673.1 - 6.8e-09 36.3 0.0 1.3e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX33673.1 - 5.6e-08 32.7 0.0 8.2e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EKX33673.1 - 2e-06 27.7 0.0 2.6e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.18 EKX33673.1 - 1.1e-05 25.3 0.0 4.6e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 EKX33673.1 - 1.8e-05 24.4 0.0 2.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 EKX33673.1 - 2e-05 25.1 0.0 3.9e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX33673.1 - 0.00015 21.1 0.0 0.00021 20.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_3 PF01596.17 EKX33673.1 - 0.0014 17.8 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.7 EKX33673.1 - 0.0035 17.3 0.0 0.0058 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EKX33673.1 - 0.005 16.4 0.0 0.0091 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EKX33673.1 - 0.0081 15.6 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) tRNA_U5-meth_tr PF05958.11 EKX33673.1 - 0.012 14.7 0.0 0.017 14.1 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase TRM PF02005.16 EKX33673.1 - 0.059 12.5 0.0 0.069 12.3 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase N6_Mtase PF02384.16 EKX33673.1 - 0.072 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase Methyltransf_12 PF08242.12 EKX33673.1 - 0.13 13.1 0.0 0.24 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_5 PF01795.19 EKX33673.1 - 0.14 11.7 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family GYF PF02213.16 EKX33674.1 - 0.0025 17.4 0.0 0.0065 16.1 0.0 1.7 1 0 0 1 1 1 1 GYF domain BUD22 PF09073.10 EKX33674.1 - 0.064 12.6 25.9 0.036 13.4 17.0 2.0 2 0 0 2 2 2 0 BUD22 DBR1 PF05011.13 EKX33674.1 - 0.17 12.3 0.2 0.17 12.3 0.2 2.1 2 0 0 2 2 2 0 Lariat debranching enzyme, C-terminal domain Vfa1 PF08432.10 EKX33674.1 - 2.4 8.5 15.6 10 6.4 10.2 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Presenilin PF01080.17 EKX33674.1 - 2.5 6.8 13.5 0.59 8.8 7.5 2.0 2 0 0 2 2 2 0 Presenilin DUF2052 PF09747.9 EKX33674.1 - 4 7.5 25.1 0.62 10.2 1.9 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) START PF01852.19 EKX33675.1 - 1.7e-09 37.4 0.0 1.8e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 START domain Polyketide_cyc2 PF10604.9 EKX33675.1 - 8.2e-05 22.9 0.1 0.00018 21.8 0.1 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EKX33675.1 - 0.0017 18.5 0.1 0.0027 17.9 0.1 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 EKX33675.1 - 0.02 15.1 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 Activator of Hsp90 ATPase homolog 1-like protein ZU5 PF00791.20 EKX33680.1 - 6.9e-06 26.3 0.0 1.2e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 ZU5 domain EF-hand_6 PF13405.6 EKX33682.1 - 0.00012 21.8 2.7 0.0032 17.3 0.1 3.1 4 0 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.6 EKX33682.1 - 0.0035 17.1 3.6 0.095 12.6 0.9 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 EKX33682.1 - 0.0087 16.5 3.6 0.6 10.6 3.4 3.0 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX33682.1 - 0.031 13.8 10.7 0.11 12.1 1.4 3.5 4 1 0 4 4 4 0 EF hand EF-hand_5 PF13202.6 EKX33682.1 - 0.1 12.2 7.5 0.75 9.4 0.6 3.2 3 0 0 3 3 3 0 EF hand TIG PF01833.24 EKX33683.1 - 2.3e-09 37.2 0.2 8.8e-09 35.3 0.0 2.1 2 0 0 2 2 2 1 IPT/TIG domain IQ PF00612.27 EKX33684.1 - 0.00085 18.9 0.1 0.0023 17.6 0.1 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif ApoLp-III PF07464.11 EKX33684.1 - 0.14 12.3 17.7 0.29 11.2 8.8 2.5 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) PID PF00640.23 EKX33684.1 - 0.33 11.0 0.1 0.33 11.0 0.1 3.5 3 1 1 4 4 4 0 Phosphotyrosine interaction domain (PTB/PID) SH3_2 PF07653.17 EKX33686.1 - 1.4e-06 27.9 0.1 3.8e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 EKX33686.1 - 1.6e-05 24.6 0.0 3.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EKX33686.1 - 0.0015 18.1 0.0 0.0064 16.1 0.0 2.1 1 0 0 1 1 1 1 SH3 domain Peptidase_Prp PF04327.12 EKX33686.1 - 0.012 15.8 0.1 0.039 14.2 0.1 1.8 1 0 0 1 1 1 0 Cysteine protease Prp Granin PF01271.17 EKX33686.1 - 0.4 9.5 1.8 0.68 8.8 1.8 1.3 1 0 0 1 1 1 0 Granin (chromogranin or secretogranin) DUF1077 PF06417.12 EKX33687.1 - 2.5e-32 111.3 1.3 3.4e-32 110.9 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) GIT1_C PF12205.8 EKX33688.1 - 0.0017 18.5 0.0 0.033 14.3 0.1 2.1 2 0 0 2 2 2 1 G protein-coupled receptor kinase-interacting protein 1 C term Actin PF00022.19 EKX33691.1 - 2.9e-135 451.0 0.0 9.7e-135 449.3 0.0 1.6 1 1 0 1 1 1 1 Actin LRR_8 PF13855.6 EKX33693.1 - 1.2e-34 117.8 73.2 1.5e-08 34.2 5.8 8.5 8 0 0 8 8 8 6 Leucine rich repeat LRR_4 PF12799.7 EKX33693.1 - 8.2e-28 96.0 67.8 1.6e-05 25.2 1.4 10.6 8 2 1 10 10 10 8 Leucine Rich repeats (2 copies) Beta_helix PF13229.6 EKX33693.1 - 1.8e-24 86.3 2.1 1.4e-17 64.0 0.0 3.0 2 1 1 3 3 3 2 Right handed beta helix region NosD PF05048.13 EKX33693.1 - 1.2e-17 64.0 2.4 7.1e-13 48.4 0.0 3.4 2 1 1 3 3 3 2 Periplasmic copper-binding protein (NosD) DUF1118 PF06549.12 EKX33693.1 - 0.11 12.8 0.1 0.11 12.8 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1118) LRR_1 PF00560.33 EKX33693.1 - 0.11 13.1 62.1 5 8.1 3.5 14.0 14 1 0 14 14 14 0 Leucine Rich Repeat LRR_9 PF14580.6 EKX33693.1 - 0.13 11.7 26.4 0.11 12.0 0.5 4.8 4 1 0 5 5 5 0 Leucine-rich repeat LRR_5 PF13306.6 EKX33693.1 - 0.34 10.9 1.6 3.4 7.6 0.6 2.9 3 0 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) Exonuc_VII_L PF02601.15 EKX33694.1 - 0.02 14.5 1.6 0.027 14.0 1.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fungal_TACC PF12709.7 EKX33694.1 - 0.32 11.5 8.0 1.4 9.4 0.5 2.3 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Uso1_p115_C PF04871.13 EKX33694.1 - 0.97 9.8 10.7 1.5 9.2 10.7 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region MFS_1 PF07690.16 EKX33695.1 - 9e-26 90.6 10.5 1.2e-25 90.2 10.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EKX33695.1 - 0.0041 16.0 5.3 0.0041 16.0 5.3 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter GspL_C PF12693.7 EKX33696.1 - 0.00022 21.1 1.1 0.00022 21.1 1.1 2.1 2 0 0 2 2 2 1 GspL periplasmic domain RWP-RK PF02042.15 EKX33697.1 - 2e-07 30.9 0.0 5e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 RWP-RK domain HRDC PF00570.23 EKX33698.1 - 7.1e-15 54.7 0.0 1.3e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 HRDC domain Helicase_Sgs1 PF11408.8 EKX33698.1 - 0.00017 21.6 0.0 0.00035 20.6 0.0 1.5 1 0 0 1 1 1 1 Sgs1 RecQ helicase CNDH2_C PF16858.5 EKX33698.1 - 0.0074 16.2 4.1 0.023 14.6 0.5 2.1 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term FYDLN_acid PF09538.10 EKX33698.1 - 7.1 7.4 15.1 6.6 7.5 7.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) PRP38 PF03371.15 EKX33699.1 - 1.1e-53 181.7 0.1 1.4e-53 181.4 0.1 1.1 1 0 0 1 1 1 1 PRP38 family Rhodanese PF00581.20 EKX33700.1 - 3.1e-06 27.6 0.0 4.4e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Myb_DNA-binding PF00249.31 EKX33701.1 - 7.8e-11 42.0 0.0 9e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF1722 PF08349.11 EKX33701.1 - 0.015 15.6 0.1 0.017 15.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) Myb_DNA-bind_7 PF15963.5 EKX33701.1 - 0.016 15.0 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 EKX33701.1 - 0.1 12.8 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 Myb-like DNA-binding domain DnaJ-X PF14308.6 EKX33702.1 - 0.022 14.2 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 X-domain of DnaJ-containing Acetyltransf_1 PF00583.25 EKX33703.1 - 0.00014 22.1 0.0 0.00046 20.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EKX33703.1 - 0.028 14.8 0.0 0.073 13.5 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.25 EKX33704.1 - 2.1e-28 99.4 0.0 2.2e-28 99.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX33704.1 - 3.6e-16 59.2 0.0 4.3e-16 59.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX33704.1 - 0.0043 16.4 0.0 0.0049 16.3 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX33704.1 - 0.0052 16.7 0.0 0.0052 16.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EKX33704.1 - 0.0057 15.6 0.0 0.0075 15.2 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EKX33704.1 - 0.0061 15.9 0.0 0.0062 15.9 0.0 1.0 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EKX33704.1 - 0.013 14.3 0.0 0.015 14.1 0.0 1.0 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 EKX33704.1 - 0.021 13.9 0.0 0.023 13.7 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 SURF1 PF02104.15 EKX33705.1 - 1.6e-20 74.0 0.0 9.6e-13 48.7 0.0 2.1 1 1 1 2 2 2 2 SURF1 family WD40 PF00400.32 EKX33711.1 - 3.1e-13 50.0 15.0 1.3e-05 25.8 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX33711.1 - 2.5e-08 34.1 0.4 0.1 12.9 0.0 3.7 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX33711.1 - 0.032 13.2 0.1 3 6.7 0.0 3.0 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ATG2_CAD PF13329.6 EKX33712.1 - 0.09 12.5 0.0 0.31 10.8 0.0 1.9 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif PRIMA1 PF16101.5 EKX33712.1 - 1.2 9.2 5.1 0.66 10.0 1.5 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Aldedh PF00171.22 EKX33713.1 - 1e-17 63.8 7.8 1e-13 50.6 5.2 2.5 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.11 EKX33713.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) DUF4637 PF15470.6 EKX33714.1 - 0.0047 16.7 1.6 0.0063 16.3 1.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4637) NAD_Gly3P_dh_N PF01210.23 EKX33715.1 - 1.2e-47 161.8 0.0 1.8e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EKX33715.1 - 2.4e-46 157.5 0.1 4.3e-46 156.7 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Semialdhyde_dh PF01118.24 EKX33715.1 - 0.0072 16.8 0.0 0.035 14.5 0.0 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DUF4215 PF13948.6 EKX33716.1 - 1.6e-07 31.7 3.3 1.6e-07 31.7 3.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4215) DUF4215 PF13948.6 EKX33717.1 - 1.6e-07 31.7 3.3 1.6e-07 31.7 3.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4215) Mhr1 PF12829.7 EKX33718.1 - 0.0066 16.5 1.3 2.4 8.3 0.1 2.5 2 0 0 2 2 2 2 Transcriptional regulation of mitochondrial recombination DUF1664 PF07889.12 EKX33718.1 - 0.059 13.4 6.7 6.2 6.9 5.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4709 PF15821.5 EKX33718.1 - 0.096 13.0 4.4 0.29 11.5 4.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4709) Allexi_40kDa PF05549.11 EKX33718.1 - 0.41 10.1 1.8 0.69 9.4 1.8 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein DcuC PF03606.15 EKX33718.1 - 0.84 8.0 3.3 1.4 7.3 3.3 1.3 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Fur_reg_FbpB PF13040.6 EKX33720.1 - 5.9 6.5 10.8 1.3 8.6 6.7 1.9 2 0 0 2 2 2 0 Fur-regulated basic protein B Cwf_Cwc_15 PF04889.12 EKX33721.1 - 0.0019 18.0 7.8 0.0031 17.3 7.8 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein GCIP PF13324.6 EKX33721.1 - 0.0072 16.0 3.6 0.01 15.5 3.6 1.2 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting CENP-B_dimeris PF09026.10 EKX33721.1 - 0.02 15.2 10.1 0.02 15.2 10.1 1.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain BUD22 PF09073.10 EKX33721.1 - 0.039 13.3 0.2 0.055 12.8 0.2 1.2 1 0 0 1 1 1 0 BUD22 FAM176 PF14851.6 EKX33721.1 - 0.3 10.7 2.4 0.31 10.7 1.3 1.5 2 0 0 2 2 2 0 FAM176 family NOA36 PF06524.12 EKX33721.1 - 0.66 9.2 8.2 0.99 8.7 8.2 1.2 1 0 0 1 1 1 0 NOA36 protein TFIIA PF03153.13 EKX33721.1 - 1.6 8.6 8.3 2 8.3 8.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EmrE PF13536.6 EKX33722.1 - 0.073 12.7 4.3 2.3 7.8 0.6 2.0 1 1 1 2 2 2 0 Putative multidrug resistance efflux transporter G10 PF01125.17 EKX33722.1 - 2.7 7.8 12.4 9.6 6.0 0.2 2.8 1 1 1 2 2 2 0 G10 protein DUF3556 PF12077.8 EKX33722.1 - 9.6 4.5 11.3 7.9 4.8 2.9 2.0 1 1 1 2 2 2 0 Transmembrane protein of unknown function (DUF3556) Cro PF09048.10 EKX33723.1 - 0.07 13.2 0.3 0.14 12.2 0.3 1.5 1 0 0 1 1 1 0 Cro NTP_transf_6 PF06042.11 EKX33723.1 - 0.08 12.8 0.1 0.15 11.9 0.0 1.5 1 1 0 1 1 1 0 Nucleotidyltransferase NTP_transf_6 PF06042.11 EKX33725.1 - 0.071 13.0 0.6 0.093 12.6 0.6 1.3 1 1 0 1 1 1 0 Nucleotidyltransferase KorB PF08535.10 EKX33725.1 - 0.18 11.8 3.3 0.64 10.1 0.1 2.0 1 1 1 2 2 2 0 KorB domain NTP_transf_6 PF06042.11 EKX33726.1 - 0.043 13.7 0.2 0.053 13.4 0.2 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase MFS_5 PF05631.14 EKX33727.1 - 1.4e-48 165.6 1.8 1.1e-29 103.5 0.0 2.3 2 0 0 2 2 2 2 Sugar-tranasporters, 12 TM OAD_gamma PF04277.13 EKX33727.1 - 0.012 16.1 0.1 5.3 7.7 0.0 2.9 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Ion_trans PF00520.31 EKX33728.1 - 0.14 11.4 0.1 0.21 10.8 0.1 1.2 1 0 0 1 1 1 0 Ion transport protein MarC PF01914.17 EKX33728.1 - 0.27 10.6 0.9 3.5 7.0 0.1 2.1 2 0 0 2 2 2 0 MarC family integral membrane protein HEPN_Toprim_N PF18871.1 EKX33728.1 - 0.41 10.5 4.4 0.45 10.4 0.3 2.2 1 1 0 2 2 2 0 HEPN/Toprim N-terminal domain 1 MscS_TM PF12794.7 EKX33728.1 - 1.1 8.1 3.6 7.2 5.4 0.8 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 HTH_3 PF01381.22 EKX33741.1 - 0.16 12.1 0.3 0.28 11.3 0.3 1.4 1 0 0 1 1 1 0 Helix-turn-helix HTH_3 PF01381.22 EKX33742.1 - 0.039 14.0 0.1 0.067 13.3 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix HTH_35 PF13693.6 EKX33742.1 - 0.11 12.5 0.1 4 7.6 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_3 PF01381.22 EKX33743.1 - 0.041 13.9 0.2 0.085 12.9 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix HTH_3 PF01381.22 EKX33745.1 - 0.04 14.0 0.2 0.082 13.0 0.2 1.4 1 0 0 1 1 1 0 Helix-turn-helix HTH_3 PF01381.22 EKX33747.1 - 0.16 12.1 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix HTH_3 PF01381.22 EKX33748.1 - 0.16 12.0 0.1 0.36 10.9 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix HTH_3 PF01381.22 EKX33750.1 - 0.18 11.9 0.1 0.39 10.8 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix CENP-R PF06729.12 EKX33751.1 - 0.14 12.0 0.3 0.82 9.6 0.3 2.0 1 1 0 1 1 1 0 Kinetochore component, CENP-R RNA_pol_Rpo13 PF12136.8 EKX33751.1 - 4.9 7.1 11.1 13 5.8 6.0 2.8 3 0 0 3 3 3 0 RNA polymerase Rpo13 subunit HTH domain LRR_9 PF14580.6 EKX33752.1 - 2.9e-68 228.8 5.0 3.8e-68 228.4 5.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EKX33752.1 - 1.8e-05 25.0 23.3 0.0052 17.2 10.3 3.6 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX33752.1 - 0.001 18.8 9.0 0.001 18.8 9.0 2.7 2 1 1 3 3 3 2 Leucine rich repeat GA PF01468.17 EKX33752.1 - 1.3 9.4 6.1 1.1 9.6 0.4 2.5 2 0 0 2 2 2 0 GA module Sec2p PF06428.11 EKX33753.1 - 0.026 14.5 0.5 0.17 11.9 0.6 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Myb_DNA-binding PF00249.31 EKX33754.1 - 8.3e-11 41.9 0.0 1.9e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3225 PF11533.8 EKX33754.1 - 0.047 13.4 0.1 0.077 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3225) Uso1_p115_C PF04871.13 EKX33754.1 - 1.4 9.3 6.4 13 6.2 2.0 2.5 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Chloroa_b-bind PF00504.21 EKX33755.1 - 1.1e-40 139.9 0.0 1.4e-40 139.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Pkinase PF00069.25 EKX33756.1 - 1.1e-67 228.1 0.0 1.4e-67 227.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX33756.1 - 8.4e-36 123.6 0.0 1e-35 123.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EKX33756.1 - 1.1e-08 34.5 0.1 1.5e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EKX33756.1 - 0.011 15.0 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX33756.1 - 0.022 14.7 0.0 0.26 11.2 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 EKX33756.1 - 0.061 12.9 0.1 0.11 12.1 0.1 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Not1 PF04054.15 EKX33757.1 - 0.0024 16.8 0.0 0.0029 16.6 0.0 1.1 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 HEAT_2 PF13646.6 EKX33757.1 - 0.13 12.6 3.3 8.1 6.9 0.8 3.0 2 1 1 3 3 3 0 HEAT repeats Vac14_Fab1_bd PF12755.7 EKX33758.1 - 0.014 15.9 2.3 0.62 10.7 0.0 5.0 5 1 0 5 5 5 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EKX33758.1 - 0.07 13.4 15.5 15 6.2 0.1 7.4 8 0 0 8 8 8 0 HEAT repeat DUF2457 PF10446.9 EKX33758.1 - 0.19 10.8 11.4 0.68 9.0 11.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Wzy_C PF04932.15 EKX33758.1 - 0.25 10.9 2.8 0.34 10.5 1.7 1.7 2 0 0 2 2 2 0 O-Antigen ligase AAA_11 PF13086.6 EKX33758.1 - 0.67 9.7 8.8 2.7 7.7 8.8 2.0 1 0 0 1 1 1 0 AAA domain FAM60A PF15396.6 EKX33758.1 - 0.92 9.5 9.0 0.32 11.0 4.4 2.6 2 0 0 2 2 2 0 Protein Family FAM60A EIIBC-GUT_N PF03612.14 EKX33758.1 - 1.5 8.6 3.9 3.5 7.3 3.9 1.6 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Coilin_N PF15862.5 EKX33758.1 - 2.4 8.0 10.1 9.4 6.0 10.1 2.1 1 0 0 1 1 1 0 Coilin N-terminus Glyco_transf_21 PF13506.6 EKX33759.1 - 1.2e-05 24.9 0.0 0.0018 17.8 0.0 2.2 1 1 1 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EKX33759.1 - 0.0029 17.4 0.0 0.0051 16.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 HTH_Tnp_1 PF01527.20 EKX33759.1 - 0.17 12.2 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 Transposase DUF4083 PF13314.6 EKX33759.1 - 1.7 8.7 5.5 47 4.0 5.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) PhoR PF11808.8 EKX33759.1 - 5.9 7.4 6.1 28 5.2 2.3 2.6 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR MgtE_N PF03448.17 EKX33761.1 - 9.7e-62 205.9 71.6 1.8e-09 38.1 1.2 11.4 2 2 12 14 14 14 13 MgtE intracellular N domain RisS_PPD PF16524.5 EKX33761.1 - 0.053 13.8 14.5 6.9 7.0 0.1 6.3 5 1 2 7 7 7 0 Periplasmic domain of Sensor histidine kinase RisS Gluconate_2-dh3 PF13618.6 EKX33761.1 - 0.083 13.1 5.0 18 5.6 0.1 5.2 6 0 0 6 6 6 0 Gluconate 2-dehydrogenase subunit 3 Spexin PF15171.6 EKX33761.1 - 0.24 11.6 1.3 87 3.4 0.0 4.4 3 0 0 3 3 3 0 Neuropeptide secretory protein family, NPQ, spexin FliG_N PF14842.6 EKX33761.1 - 0.55 10.8 25.0 3.1 8.4 0.4 8.5 7 3 3 10 10 10 0 FliG N-terminal domain Utp12 PF04003.12 EKX33761.1 - 0.67 10.3 16.5 6 7.2 0.4 6.1 6 0 0 6 6 6 0 Dip2/Utp12 Family FliG_M PF14841.6 EKX33761.1 - 0.73 10.1 23.6 22 5.3 0.1 9.9 9 2 3 12 12 12 0 FliG middle domain UBM PF14377.6 EKX33761.1 - 3.6 7.2 7.0 0.47 10.0 1.0 2.8 2 0 0 2 2 2 0 Ubiquitin binding region NAD_binding_10 PF13460.6 EKX33762.1 - 1.1e-16 61.3 0.1 1.8e-16 60.6 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EKX33762.1 - 7e-06 25.7 0.0 1.9e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EKX33762.1 - 2.5e-05 23.4 0.2 5.4e-05 22.3 0.1 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EKX33762.1 - 0.049 12.7 0.0 0.12 11.5 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain KR PF08659.10 EKX33762.1 - 0.062 13.2 0.1 0.11 12.4 0.1 1.5 1 1 0 1 1 1 0 KR domain THF_DHG_CYH_C PF02882.19 EKX33762.1 - 0.092 12.1 0.1 0.19 11.0 0.1 1.5 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.13 EKX33762.1 - 0.18 11.3 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Pkinase_Tyr PF07714.17 EKX33763.1 - 5.3e-65 219.3 0.0 5.9e-65 219.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX33763.1 - 1.3e-28 100.2 0.0 1.4e-28 100.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EKX33763.1 - 0.3 10.4 0.6 0.5 9.6 0.7 1.5 1 1 0 1 1 1 0 Kinase-like Peptidase_S8 PF00082.22 EKX33764.1 - 5.6e-40 137.5 3.3 7.9e-40 137.0 3.3 1.2 1 0 0 1 1 1 1 Subtilase family PAP_fibrillin PF04755.12 EKX33765.1 - 0.0043 17.0 0.0 0.015 15.3 0.0 1.7 1 1 0 1 1 1 1 PAP_fibrillin RabGAP-TBC PF00566.18 EKX33766.1 - 1.6e-39 135.8 0.0 1.8e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Mhr1 PF12829.7 EKX33766.1 - 0.026 14.6 0.0 0.045 13.8 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulation of mitochondrial recombination Peptidase_S8 PF00082.22 EKX33767.1 - 6.4e-40 137.3 3.3 9.1e-40 136.8 3.3 1.2 1 0 0 1 1 1 1 Subtilase family RNase_PH PF01138.21 EKX33768.1 - 5.5e-18 65.7 0.7 8.2e-18 65.2 0.2 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EKX33768.1 - 1.8e-05 24.7 0.0 3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 AAA PF00004.29 EKX33771.1 - 7.6e-89 294.9 0.0 3.1e-47 160.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EKX33771.1 - 7e-26 89.8 8.6 2.9e-12 46.2 4.3 3.5 3 1 0 3 3 2 2 AAA+ lid domain AAA_16 PF13191.6 EKX33771.1 - 4e-15 56.6 2.7 1.7e-05 25.3 0.0 4.8 4 2 0 4 4 4 2 AAA ATPase domain RuvB_N PF05496.12 EKX33771.1 - 2.8e-13 49.9 0.0 1.7e-05 24.6 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EKX33771.1 - 4.4e-13 49.7 0.0 1.3e-05 25.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EKX33771.1 - 3.4e-12 46.6 0.0 4.3e-06 26.8 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EKX33771.1 - 5.4e-11 42.9 0.7 0.0078 16.5 0.1 4.6 3 2 0 3 3 2 2 AAA domain AAA_33 PF13671.6 EKX33771.1 - 2.9e-10 40.5 0.2 0.0026 17.9 0.4 3.4 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EKX33771.1 - 1.3e-09 38.0 0.0 3.4e-05 23.6 0.0 2.6 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.6 EKX33771.1 - 9.2e-09 35.2 5.2 0.032 13.8 0.1 4.1 2 2 1 4 4 4 3 AAA domain RNA_helicase PF00910.22 EKX33771.1 - 7.4e-08 32.7 0.0 0.036 14.5 0.0 3.4 3 1 0 3 3 2 2 RNA helicase TIP49 PF06068.13 EKX33771.1 - 1.4e-07 31.1 0.1 0.0088 15.3 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 EKX33771.1 - 2.5e-07 30.8 0.0 0.025 14.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EKX33771.1 - 3.9e-07 29.7 0.3 0.015 14.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EKX33771.1 - 5.2e-07 30.3 3.4 0.021 15.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.6 EKX33771.1 - 3.6e-06 27.3 0.0 0.051 13.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 EKX33771.1 - 3.9e-06 26.3 0.1 0.036 13.3 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin Sigma54_activat PF00158.26 EKX33771.1 - 1.1e-05 25.2 0.1 0.37 10.5 0.0 3.8 3 1 0 3 3 3 2 Sigma-54 interaction domain NACHT PF05729.12 EKX33771.1 - 1.5e-05 25.0 0.3 0.066 13.1 0.0 3.4 4 0 0 4 4 3 2 NACHT domain ABC_tran PF00005.27 EKX33771.1 - 3e-05 24.6 0.0 0.49 10.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter Vps4_C PF09336.10 EKX33771.1 - 3.2e-05 23.8 0.1 0.033 14.2 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_17 PF13207.6 EKX33771.1 - 6.6e-05 23.4 0.8 0.14 12.5 0.0 3.1 3 0 0 3 3 2 1 AAA domain ATPase PF06745.13 EKX33771.1 - 9.5e-05 21.9 0.7 2.7 7.3 0.0 3.3 2 1 0 3 3 3 1 KaiC Rad17 PF03215.15 EKX33771.1 - 0.00012 22.1 0.0 0.0073 16.2 0.0 2.5 2 1 0 2 2 2 1 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 EKX33771.1 - 0.00013 22.1 0.0 0.44 10.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_7 PF12775.7 EKX33771.1 - 0.0002 20.9 0.0 0.9 9.0 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region TsaE PF02367.17 EKX33771.1 - 0.0006 19.8 0.0 0.26 11.3 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 EKX33771.1 - 0.0008 19.3 0.0 0.9 9.4 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EKX33771.1 - 0.00088 18.5 0.0 0.85 8.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_11 PF13086.6 EKX33771.1 - 0.001 19.0 0.7 2.5 7.8 0.0 2.9 2 1 0 2 2 2 2 AAA domain PhoH PF02562.16 EKX33771.1 - 0.0011 18.5 0.0 1 8.8 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein Zot PF05707.12 EKX33771.1 - 0.0014 18.3 0.2 0.11 12.1 0.1 3.3 2 2 0 2 2 2 1 Zonular occludens toxin (Zot) NB-ARC PF00931.22 EKX33771.1 - 0.0022 17.2 0.0 2.2 7.4 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_24 PF13479.6 EKX33771.1 - 0.0024 17.6 0.0 0.75 9.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EKX33771.1 - 0.0033 17.2 2.4 0.2 11.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain Viral_helicase1 PF01443.18 EKX33771.1 - 0.0079 16.0 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 EKX33771.1 - 0.0081 16.1 0.0 1.6 8.6 0.0 2.9 2 2 1 3 3 2 1 ATPase domain predominantly from Archaea AAA_29 PF13555.6 EKX33771.1 - 0.0084 15.8 0.1 0.38 10.5 0.0 2.7 3 0 0 3 3 2 1 P-loop containing region of AAA domain NTPase_1 PF03266.15 EKX33771.1 - 0.01 15.8 0.1 4.6 7.1 0.0 3.2 2 1 1 3 3 3 0 NTPase Parvo_NS1 PF01057.17 EKX33771.1 - 0.01 14.9 0.0 2.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Cytidylate_kin PF02224.18 EKX33771.1 - 0.011 15.5 0.2 3.6 7.3 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase AAA_19 PF13245.6 EKX33771.1 - 0.012 16.0 0.3 6.1 7.2 0.0 2.7 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EKX33771.1 - 0.029 13.6 0.0 3.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.14 EKX33771.1 - 0.052 12.8 0.1 38 3.4 0.0 3.2 2 2 1 3 3 3 0 KAP family P-loop domain HTH_20 PF12840.7 EKX33771.1 - 0.073 13.1 1.3 6.6 6.9 0.2 3.1 2 0 0 2 2 2 0 Helix-turn-helix domain KTI12 PF08433.10 EKX33771.1 - 0.077 12.4 0.1 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 APS_kinase PF01583.20 EKX33771.1 - 0.088 12.7 0.0 2.6 7.9 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase Hydin_ADK PF17213.3 EKX33771.1 - 0.11 12.8 4.7 16 5.7 0.0 3.6 4 0 0 4 4 3 0 Hydin Adenylate kinase-like domain Torsin PF06309.11 EKX33771.1 - 0.21 11.7 0.0 3.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Torsin Ribosomal_L19e PF01280.20 EKX33771.1 - 0.38 10.8 2.6 23 5.0 0.5 2.9 3 0 0 3 3 3 0 Ribosomal protein L19e TPR_16 PF13432.6 EKX33772.1 - 1.1e-05 25.9 0.6 1.1e-05 25.9 0.6 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Glyco_transf_41 PF13844.6 EKX33772.1 - 0.00056 18.5 0.1 0.00072 18.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 41 TPR_2 PF07719.17 EKX33772.1 - 0.00083 19.3 3.0 0.88 9.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX33772.1 - 0.0096 15.7 0.2 6.2 6.8 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX33772.1 - 0.012 16.0 0.1 0.043 14.2 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 EKX33772.1 - 0.028 14.5 1.4 0.1 12.8 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX33772.1 - 0.043 14.1 0.0 0.094 12.9 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EKX33772.1 - 0.044 14.6 1.4 0.19 12.6 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat CUE PF02845.16 EKX33772.1 - 0.13 12.0 0.2 0.5 10.1 0.0 2.1 2 0 0 2 2 2 0 CUE domain TPR_12 PF13424.6 EKX33772.1 - 0.27 11.5 3.4 1.3 9.3 0.3 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.16 EKX33773.1 - 4.6e-14 52.1 19.7 8.1e-14 51.3 19.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 EKX33773.1 - 2.6e-11 42.8 6.4 3.7e-11 42.2 6.4 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein Ion_trans PF00520.31 EKX33774.1 - 3.3e-22 78.9 13.7 2.3e-21 76.2 13.7 2.0 1 1 0 1 1 1 1 Ion transport protein PH PF00169.29 EKX33774.1 - 1.3e-05 25.7 0.0 2.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 PH domain EF-hand_6 PF13405.6 EKX33774.1 - 0.017 15.0 1.0 0.083 12.9 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain PTRF_SDPR PF15237.6 EKX33774.1 - 0.065 12.8 3.1 4.9 6.7 0.2 2.5 2 0 0 2 2 2 0 PTRF/SDPR family EF-hand_1 PF00036.32 EKX33774.1 - 0.16 11.6 0.4 1.1 8.9 0.0 2.8 2 0 0 2 2 2 0 EF hand DUF2207 PF09972.9 EKX33774.1 - 0.63 8.7 2.4 2.5 6.8 0.6 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) PKD_channel PF08016.12 EKX33774.1 - 0.76 8.4 11.0 2.7 6.6 5.1 2.4 1 1 1 2 2 2 0 Polycystin cation channel Glyco_transf_41 PF13844.6 EKX33775.1 - 2.3e-88 296.7 0.0 6.5e-50 169.9 0.0 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_2 PF07719.17 EKX33775.1 - 6.9e-30 100.7 20.8 0.00053 19.9 0.0 8.6 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_1 PF00515.28 EKX33775.1 - 1.8e-29 100.3 18.5 1.4e-05 24.7 0.0 8.3 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_11 PF13414.6 EKX33775.1 - 3.4e-19 68.3 22.4 1.7e-06 27.6 0.0 7.5 6 2 1 7 7 7 4 TPR repeat TPR_8 PF13181.6 EKX33775.1 - 4.6e-19 67.0 16.6 0.0063 16.6 0.0 8.1 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.6 EKX33775.1 - 3.7e-17 61.4 7.0 0.00047 20.3 0.0 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX33775.1 - 6.5e-14 52.0 22.7 5.3e-07 29.8 0.1 5.9 3 2 2 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX33775.1 - 9.4e-14 50.4 8.6 0.13 12.3 0.1 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 EKX33775.1 - 7e-13 49.0 18.5 0.00034 21.2 2.5 5.4 5 2 0 6 6 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX33775.1 - 6.2e-11 42.2 17.5 0.14 13.1 0.0 8.1 4 3 4 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EKX33775.1 - 8.8e-10 39.0 11.2 5.8e-05 23.5 0.9 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX33775.1 - 1.9e-08 34.4 14.0 0.2 12.4 0.1 7.3 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX33775.1 - 1e-07 31.6 18.7 0.015 15.2 0.3 6.4 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 EKX33775.1 - 0.00014 22.0 6.1 0.039 14.1 0.1 4.2 3 1 0 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.17 EKX33775.1 - 0.00055 20.4 0.9 0.00055 20.4 0.9 4.1 4 1 0 5 5 3 1 Bacterial transcriptional activator domain TOM20_plant PF06552.12 EKX33775.1 - 0.00057 19.7 1.8 0.67 9.7 0.1 2.4 2 0 0 2 2 2 2 Plant specific mitochondrial import receptor subunit TOM20 TPR_4 PF07721.14 EKX33775.1 - 0.0014 19.1 6.7 3.2 8.7 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF2225 PF09986.9 EKX33775.1 - 0.031 14.0 2.0 0.72 9.5 0.4 3.0 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_3 PF07720.12 EKX33775.1 - 0.031 14.3 1.2 6.6 6.8 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 EKX33775.1 - 0.037 14.1 9.5 1.2 9.3 0.5 4.4 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain DUF3856 PF12968.7 EKX33775.1 - 0.04 14.0 4.3 0.53 10.4 0.1 4.0 4 1 0 4 4 4 0 Domain of Unknown Function (DUF3856) NARP1 PF12569.8 EKX33775.1 - 0.084 11.8 1.9 13 4.5 0.1 3.1 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 Alkyl_sulf_dimr PF14863.6 EKX33775.1 - 0.12 12.8 1.3 0.22 12.0 0.3 2.0 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation Mad3_BUB1_I PF08311.12 EKX33775.1 - 2.7 8.0 8.5 32 4.5 0.1 4.1 5 0 0 5 5 4 0 Mad3/BUB1 homology region 1 Ank_3 PF13606.6 EKX33776.1 - 9.7e-12 44.0 0.0 0.00018 21.7 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EKX33776.1 - 2.4e-11 44.1 0.1 3.8e-11 43.4 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX33776.1 - 1.8e-08 34.8 0.1 4.6e-08 33.5 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX33776.1 - 1.8e-07 31.3 0.3 8.6e-07 29.1 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX33776.1 - 7.3e-05 23.0 1.2 0.0012 19.1 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat SNARE_assoc PF09335.11 EKX33777.1 - 1.6e-24 86.7 8.2 1.6e-24 86.7 8.2 1.6 2 0 0 2 2 2 1 SNARE associated Golgi protein PH PF00169.29 EKX33780.1 - 6.4e-06 26.6 0.3 6.4e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 EKX33780.1 - 0.051 14.0 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Peptidase_S28 PF05577.12 EKX33782.1 - 0.0023 16.8 1.4 0.0028 16.5 1.4 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Ion_trans PF00520.31 EKX33783.1 - 6.9e-10 38.6 2.5 9.5e-10 38.1 2.5 1.1 1 0 0 1 1 1 1 Ion transport protein PH PF00169.29 EKX33783.1 - 2.2e-06 28.1 0.0 3.7e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 PH domain DUF3169 PF11368.8 EKX33783.1 - 0.012 15.1 0.1 0.022 14.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Adeno_E3A PF05248.12 EKX33785.1 - 0.00012 22.0 0.6 64 3.7 0.0 7.6 1 1 7 10 10 10 0 Adenovirus E3A Gamma-thionin PF00304.20 EKX33785.1 - 0.71 10.2 4.1 97 3.3 0.2 4.7 3 2 0 3 3 3 0 Gamma-thionin family zf-NF-X1 PF01422.17 EKX33785.1 - 0.73 10.0 8.2 78 3.5 0.4 6.3 3 2 0 3 3 3 0 NF-X1 type zinc finger F5_F8_type_C PF00754.25 EKX33786.1 - 3.3e-19 69.3 0.0 4.3e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain F5_F8_type_C PF00754.25 EKX33787.1 - 2.6e-23 82.5 0.0 2.9e-23 82.4 0.0 1.0 1 0 0 1 1 1 1 F5/8 type C domain F5_F8_type_C PF00754.25 EKX33788.1 - 1.5e-21 76.8 0.1 1.6e-21 76.8 0.1 1.0 1 0 0 1 1 1 1 F5/8 type C domain SRCR PF00530.18 EKX33789.1 - 1.2e-38 131.6 19.8 1.9e-19 70.0 7.4 2.2 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 EKX33789.1 - 7.7e-09 36.0 1.5 0.00073 20.0 0.6 2.4 2 0 0 2 2 2 2 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 EKX33789.1 - 0.019 15.5 2.2 2.4 8.7 0.4 2.4 2 0 0 2 2 2 0 Hepsin, SRCR domain Rep_fac-A_C PF08646.10 EKX33791.1 - 1.7e-38 131.7 0.7 1e-32 112.9 0.1 2.3 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EKX33791.1 - 8.1e-28 96.2 3.4 1.5e-26 92.1 0.9 2.9 3 0 0 3 3 3 1 Replication protein A OB domain Rep-A_N PF04057.12 EKX33791.1 - 1.3e-25 89.3 0.4 3.1e-25 88.1 0.4 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 EKX33791.1 - 1.1e-10 41.3 0.6 2.2e-09 37.1 0.0 2.9 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain cNMP_binding PF00027.29 EKX33792.1 - 1.1e-31 108.8 0.0 2.6e-21 75.5 0.0 2.1 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Lact_bio_phlase PF09508.10 EKX33794.1 - 0.025 13.0 0.0 0.03 12.8 0.0 1.0 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase N-terminal TIM barrel domain zf-U1 PF06220.12 EKX33797.1 - 2.2e-22 78.5 2.4 2.2e-22 78.5 2.4 1.6 2 0 0 2 2 2 1 U1 zinc finger CLIP1_ZNF PF16641.5 EKX33797.1 - 0.0019 18.0 2.4 0.0028 17.5 2.4 1.3 1 0 0 1 1 1 1 CLIP1 zinc knuckle zf-met PF12874.7 EKX33797.1 - 1.5 9.3 7.4 28 5.3 6.6 2.6 2 1 0 2 2 2 0 Zinc-finger of C2H2 type Keratin_2_head PF16208.5 EKX33798.1 - 0.98 9.5 15.9 1.9 8.6 15.9 1.4 1 0 0 1 1 1 0 Keratin type II head PDZ PF00595.24 EKX33799.1 - 9.5e-09 35.5 0.6 0.00023 21.4 0.2 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX33799.1 - 7.5e-07 29.4 1.0 0.045 14.1 0.1 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EKX33799.1 - 1.8e-06 27.7 0.9 7e-05 22.6 0.4 2.7 2 0 0 2 2 2 1 PDZ domain Fib_alpha PF08702.10 EKX33799.1 - 7.8 6.7 11.9 0.99 9.6 0.1 3.2 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family PAH PF02671.21 EKX33800.1 - 1.2e-28 99.0 1.8 1.3e-15 57.2 0.0 2.2 2 0 0 2 2 2 2 Paired amphipathic helix repeat Ku_PK_bind PF08785.11 EKX33800.1 - 0.0082 16.3 1.1 1.2 9.3 0.1 2.5 1 1 2 3 3 3 2 Ku C terminal domain like DUF2150 PF09920.9 EKX33800.1 - 0.019 14.9 0.0 0.023 14.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) SIL1 PF16782.5 EKX33800.1 - 0.082 12.1 0.1 0.096 11.9 0.1 1.1 1 0 0 1 1 1 0 Nucleotide exchange factor SIL1 SIP1 PF04938.12 EKX33800.1 - 0.12 12.0 0.2 1.1 9.0 0.0 2.0 1 1 1 2 2 2 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) Ly49 PF08391.10 EKX33801.1 - 0.092 13.1 3.9 0.053 13.9 2.1 1.5 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region Asn_synthase PF00733.21 EKX33802.1 - 1.3e-77 261.8 0.6 2.6e-48 165.5 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EKX33802.1 - 5.4e-35 120.0 0.0 1.2e-34 118.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EKX33802.1 - 6.3e-27 94.4 0.0 1.8e-26 92.9 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EKX33802.1 - 4.8e-10 39.3 0.0 7.9e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 EKX33802.1 - 0.022 13.9 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 NAD synthase DUF1933 PF09147.10 EKX33802.1 - 0.039 13.6 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1933) TPR_14 PF13428.6 EKX33803.1 - 0.12 13.3 0.0 0.78 10.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPT PF03151.16 EKX33804.1 - 9.1e-89 297.6 8.2 1.1e-88 297.4 8.2 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EKX33804.1 - 2.6e-16 60.0 19.1 3.6e-10 40.2 4.9 2.6 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EKX33804.1 - 0.1 11.8 5.5 2.4 7.3 0.1 2.0 1 1 1 2 2 2 0 UAA transporter family HATPase_c PF02518.26 EKX33805.1 - 1.1e-13 51.6 0.0 3.4e-13 50.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_3 PF13492.6 EKX33805.1 - 0.00023 21.5 0.0 0.0014 19.0 0.0 2.1 1 1 0 1 1 1 1 GAF domain HATPase_c_5 PF14501.6 EKX33805.1 - 0.00027 20.8 0.1 0.0088 15.9 0.0 2.4 2 0 0 2 2 2 1 GHKL domain HATPase_c_3 PF13589.6 EKX33805.1 - 0.0036 17.1 0.0 0.0082 16.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.26 EKX33805.1 - 0.0041 17.8 0.0 0.0085 16.7 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 EKX33805.1 - 0.0075 16.6 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 GAF domain UBX PF00789.20 EKX33807.1 - 3e-16 59.4 0.0 6.5e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.6 EKX33807.1 - 9.9e-13 48.1 0.0 1.9e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UIM PF02809.20 EKX33807.1 - 0.0068 16.2 1.6 0.0068 16.2 1.6 2.2 1 1 0 1 1 1 1 Ubiquitin interaction motif DUF241 PF03087.14 EKX33808.1 - 0.01 15.7 0.5 0.039 13.8 0.0 2.1 1 1 1 2 2 2 1 Arabidopsis protein of unknown function PX PF00787.24 EKX33809.1 - 5.4e-18 65.0 0.0 8.6e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 PX domain Zip PF02535.22 EKX33810.1 - 3.1e-28 99.0 13.0 1.8e-25 89.9 3.4 2.0 2 0 0 2 2 2 2 ZIP Zinc transporter Sugar_tr PF00083.24 EKX33810.1 - 0.21 10.4 11.1 0.031 13.2 0.8 2.3 2 0 0 2 2 2 0 Sugar (and other) transporter E1-E2_ATPase PF00122.20 EKX33810.1 - 4.6 6.7 8.4 0.27 10.7 0.1 2.4 3 0 0 3 3 3 0 E1-E2 ATPase Phage_Integr_2 PF13009.6 EKX33811.1 - 0.074 12.1 0.0 0.088 11.9 0.0 1.1 1 0 0 1 1 1 0 Putative phage integrase WD40 PF00400.32 EKX33812.1 - 1.4e-20 73.2 17.6 3.4e-05 24.5 0.1 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX33812.1 - 2.1e-16 60.0 8.1 3.8e-06 27.1 0.5 4.5 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX33812.1 - 2.1e-05 23.6 1.5 0.0002 20.5 0.4 3.0 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EKX33812.1 - 0.00016 21.6 0.0 0.055 13.3 0.0 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.9 EKX33812.1 - 0.0014 18.5 1.5 0.32 10.7 0.9 2.5 2 1 0 2 2 2 2 Lipoprotein LpqB beta-propeller domain ATG22 PF11700.8 EKX33813.1 - 2.8e-20 72.4 32.2 6.3e-18 64.7 31.8 2.2 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EKX33813.1 - 9.4e-14 51.1 39.6 7.4e-06 25.1 9.4 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Halogen_Hydrol PF10112.9 EKX33813.1 - 7.1 6.6 8.6 3.5 7.6 1.5 2.5 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF2465 PF10239.9 EKX33814.1 - 2.8e-22 79.4 2.1 3.2e-22 79.2 0.2 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2465) OGG_N PF07934.12 EKX33814.1 - 0.016 15.3 3.2 0.076 13.1 0.1 2.6 3 0 0 3 3 3 0 8-oxoguanine DNA glycosylase, N-terminal domain DUF2563 PF10817.8 EKX33814.1 - 0.41 11.3 2.2 14 6.4 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2563) Myc_N PF01056.18 EKX33814.1 - 2.3 8.0 15.7 4.9 7.0 0.4 2.4 2 0 0 2 2 2 0 Myc amino-terminal region PA26 PF04636.13 EKX33814.1 - 3.7 6.4 5.4 21 3.9 4.4 2.1 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) DBR1 PF05011.13 EKX33815.1 - 7.4e-17 62.1 0.0 1.4e-16 61.2 0.0 1.5 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain DUF3381 PF11861.8 EKX33816.1 - 0.028 14.2 0.6 0.028 14.2 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) PP2C PF00481.21 EKX33817.1 - 2.2e-56 191.4 0.4 4e-56 190.5 0.4 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EKX33817.1 - 1.6e-05 24.7 0.1 2.9e-05 23.8 0.1 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C Glycolytic PF00274.19 EKX33817.1 - 0.03 13.1 0.1 0.062 12.0 0.1 1.4 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I CATSPERB PF15149.6 EKX33817.1 - 0.034 12.7 0.4 0.65 8.5 0.1 2.0 2 0 0 2 2 2 0 Cation channel sperm-associated protein subunit beta protein family E2F_CC-MB PF16421.5 EKX33818.1 - 1.1e-25 89.8 0.1 1.5e-25 89.3 0.1 1.2 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 EKX33818.1 - 2.2e-25 88.5 0.0 4.4e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain B-block_TFIIIC PF04182.12 EKX33818.1 - 0.14 12.3 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Ank_3 PF13606.6 EKX33820.1 - 1.7e-14 52.4 0.1 0.00065 20.0 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EKX33820.1 - 1.2e-13 51.2 0.0 6.6e-09 36.1 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX33820.1 - 1.5e-12 48.0 0.0 1.3e-10 41.7 0.1 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EKX33820.1 - 5e-10 39.4 0.9 0.0056 17.1 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EKX33820.1 - 2.1e-05 24.7 0.2 0.13 12.6 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Rft-1 PF04506.13 EKX33821.1 - 2.9e-53 181.4 11.9 3.6e-53 181.1 11.9 1.0 1 0 0 1 1 1 1 Rft protein DUF3741 PF12552.8 EKX33821.1 - 0.051 13.5 0.2 0.14 12.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3741) 2OG-FeII_Oxy_3 PF13640.6 EKX33822.1 - 8.1e-14 52.3 0.0 2e-13 51.0 0.0 1.7 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 EKX33822.1 - 1e-07 32.5 0.0 2.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 EKX33823.1 - 5.7e-39 134.1 0.1 2.7e-38 131.8 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX33823.1 - 1.1e-22 80.6 0.0 1.3e-22 80.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX33823.1 - 9e-08 31.3 0.1 1.2e-07 30.9 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EKX33823.1 - 0.0012 18.2 0.4 0.0016 17.8 0.4 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX33823.1 - 0.0087 16.0 0.5 0.021 14.8 0.2 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EKX33823.1 - 0.017 14.7 0.1 0.037 13.6 0.1 1.6 1 1 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 EKX33823.1 - 0.029 13.9 0.0 0.08 12.4 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 EKX33823.1 - 0.093 12.3 0.1 1 9.0 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PIP49_C PF12260.8 EKX33823.1 - 0.16 11.6 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 PARP PF00644.20 EKX33824.1 - 1e-23 83.9 0.1 1.5e-22 80.2 0.1 2.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain DNA_pol3_theta PF06440.11 EKX33824.1 - 0.097 12.3 0.1 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 DNA polymerase III, theta subunit Exotox-A_cataly PF09009.10 EKX33824.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Exotoxin A catalytic Pkinase PF00069.25 EKX33825.1 - 2.5e-71 240.1 0.1 4.6e-71 239.3 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX33825.1 - 1.7e-34 119.3 0.2 3.5e-34 118.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase CDC4_D PF16856.5 EKX33825.1 - 0.035 14.0 0.2 0.1 12.5 0.2 1.8 1 0 0 1 1 1 0 Cell division control protein 4 dimerisation domain CRT10 PF08728.10 EKX33825.1 - 1.9 6.5 13.6 2.9 6.0 13.6 1.1 1 0 0 1 1 1 0 CRT10 CDC45 PF02724.14 EKX33825.1 - 6.8 4.9 21.2 9.7 4.3 21.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Ank_2 PF12796.7 EKX33828.1 - 4e-22 78.6 0.0 7.3e-13 48.9 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX33828.1 - 9.1e-21 73.7 0.0 1.7e-09 37.7 0.0 2.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX33828.1 - 6.4e-19 67.5 0.0 1.3e-07 31.7 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EKX33828.1 - 4.8e-16 58.9 0.0 5e-09 36.5 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX33828.1 - 3.2e-13 48.6 0.0 1.7e-05 24.9 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat DUF1631 PF07793.11 EKX33829.1 - 0.0033 15.9 0.7 0.0035 15.8 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1631) RhoGAP PF00620.27 EKX33830.1 - 8.7e-09 35.4 0.1 1.9e-08 34.3 0.1 1.5 1 1 0 1 1 1 1 RhoGAP domain NDUFA12 PF05071.16 EKX33832.1 - 1.3e-12 48.4 0.3 1.6e-12 48.1 0.3 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Pex19 PF04614.12 EKX33832.1 - 0.0019 18.0 0.3 0.0023 17.7 0.3 1.1 1 0 0 1 1 1 1 Pex19 protein family TPT PF03151.16 EKX33833.1 - 1.5e-49 168.9 5.1 1.7e-49 168.7 5.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EKX33833.1 - 7.6e-06 26.1 17.9 2.5e-05 24.4 7.5 2.7 3 0 0 3 3 3 2 EamA-like transporter family DUF1240 PF06836.12 EKX33833.1 - 0.2 12.2 1.7 4.8 7.8 0.3 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1240) RWP-RK PF02042.15 EKX33834.1 - 4.5e-13 49.0 0.8 6e-13 48.5 0.1 1.6 2 0 0 2 2 2 1 RWP-RK domain Ribosomal_60s PF00428.19 EKX33834.1 - 0.01 16.4 5.0 0.015 15.9 5.0 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein HTH_8 PF02954.19 EKX33834.1 - 0.024 14.4 0.6 0.42 10.4 0.1 2.4 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family Sigma70_r4_2 PF08281.12 EKX33834.1 - 0.028 14.1 0.1 0.092 12.4 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 DUF1908 PF08926.11 EKX33834.1 - 0.1 11.6 0.1 0.12 11.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) Exo84_C PF16528.5 EKX33837.1 - 4e-23 82.3 0.2 7.7e-20 71.6 0.1 2.8 2 0 0 2 2 2 2 Exocyst component 84 C-terminal Vps51 PF08700.11 EKX33837.1 - 0.0011 19.0 0.0 0.0011 19.0 0.0 3.1 3 0 0 3 3 3 1 Vps51/Vps67 Myosin_TH1 PF06017.13 EKX33837.1 - 0.0029 17.3 0.2 0.012 15.3 0.0 2.1 2 0 0 2 2 2 1 Unconventional myosin tail, actin- and lipid-binding Syntaxin-6_N PF09177.11 EKX33837.1 - 0.46 11.1 3.7 0.68 10.5 0.1 3.2 4 0 0 4 4 4 0 Syntaxin 6, N-terminal Spt20 PF12090.8 EKX33837.1 - 0.56 9.8 4.7 1.2 8.6 4.7 1.5 1 0 0 1 1 1 0 Spt20 family COG2 PF06148.11 EKX33837.1 - 2.4 8.2 8.1 0.28 11.3 0.5 3.4 4 1 1 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF5327 PF17261.2 EKX33837.1 - 2.7 8.8 9.3 2.5 8.9 5.7 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5327) LRR_4 PF12799.7 EKX33838.1 - 8.2e-42 140.5 59.1 3.7e-07 30.4 3.1 9.8 8 2 2 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX33838.1 - 2.9e-38 129.4 57.9 6.6e-12 45.0 2.4 8.4 3 2 5 9 9 9 9 Leucine rich repeat LRR_1 PF00560.33 EKX33838.1 - 3.9e-10 38.8 48.5 3.7 8.5 0.2 14.3 13 4 1 14 14 14 5 Leucine Rich Repeat LRR_6 PF13516.6 EKX33838.1 - 8.3e-07 28.6 55.1 2.6 8.3 0.6 13.0 13 0 0 13 13 13 8 Leucine Rich repeat LRR_9 PF14580.6 EKX33838.1 - 0.0065 16.0 24.1 0.27 10.7 2.0 5.1 1 1 6 7 7 7 5 Leucine-rich repeat DUF2322 PF10084.9 EKX33838.1 - 0.052 13.6 0.0 35 4.5 0.0 4.1 4 2 1 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2322) LRR_5 PF13306.6 EKX33838.1 - 3.7 7.5 9.1 1.1 9.2 0.8 3.6 3 2 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) RWP-RK PF02042.15 EKX33842.1 - 0.12 12.4 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 RWP-RK domain Arm PF00514.23 EKX33843.1 - 5.4e-08 32.6 3.7 0.0015 18.5 0.1 5.1 6 1 0 6 6 6 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EKX33843.1 - 2.9e-07 30.4 4.0 0.0011 18.9 0.5 3.4 2 1 2 4 4 4 3 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 EKX33843.1 - 0.0043 16.5 6.1 0.79 9.1 5.8 2.7 1 1 1 2 2 2 2 Armadillo-like DUF892 PF05974.12 EKX33843.1 - 0.041 13.9 0.4 0.077 13.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF892) CRS1_YhbY PF01985.21 EKX33843.1 - 0.25 11.6 5.2 24 5.2 0.7 3.8 3 1 1 4 4 4 0 CRS1 / YhbY (CRM) domain PDZ_6 PF17820.1 EKX33844.1 - 1.2e-07 31.5 0.0 2.7e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX33844.1 - 4.9e-06 26.8 0.0 1.5e-05 25.3 0.0 1.8 1 1 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX33844.1 - 6.8e-05 23.1 0.0 0.00014 22.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Thioredoxin_8 PF13905.6 EKX33845.1 - 4.6e-28 97.4 0.0 1e-27 96.3 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like fn3 PF00041.21 EKX33845.1 - 7e-13 48.7 1.2 6e-06 26.5 0.1 2.3 2 0 0 2 2 2 2 Fibronectin type III domain Thioredoxin PF00085.20 EKX33845.1 - 9.3e-09 35.2 0.1 6.5e-06 26.1 0.1 2.5 1 1 1 2 2 2 2 Thioredoxin AhpC-TSA PF00578.21 EKX33845.1 - 1.4e-06 28.3 0.0 2.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EKX33845.1 - 1.9e-06 27.7 0.0 3.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Redoxin Pur_ac_phosph_N PF16656.5 EKX33845.1 - 1.5e-05 25.5 1.6 0.032 14.8 0.1 3.3 2 2 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain SusE PF14292.6 EKX33845.1 - 0.00051 20.2 0.1 0.0059 16.8 0.1 2.2 2 0 0 2 2 2 1 SusE outer membrane protein Thioredoxin_2 PF13098.6 EKX33845.1 - 0.0014 19.0 0.0 0.041 14.3 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin-like domain Tissue_fac PF01108.17 EKX33845.1 - 0.0017 18.2 0.6 2.2 8.2 0.1 2.5 2 0 0 2 2 2 2 Tissue factor PhoD_N PF16655.5 EKX33845.1 - 0.042 14.4 0.0 1.4 9.5 0.0 2.3 2 0 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain PMC2NT PF08066.12 EKX33846.1 - 0.19 12.4 2.1 4.6 8.0 0.7 2.7 2 1 0 2 2 2 0 PMC2NT (NUC016) domain WD40 PF00400.32 EKX33847.1 - 1.2e-55 184.1 17.5 1.4e-09 38.4 0.0 9.0 9 0 0 9 9 9 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX33847.1 - 4.8e-15 55.6 0.1 7.2e-05 23.0 0.0 6.3 2 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX33847.1 - 8.6e-11 41.4 2.5 0.0027 16.7 0.0 6.7 2 1 4 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5046 PF16465.5 EKX33847.1 - 1.3e-05 24.8 0.0 0.00027 20.5 0.1 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF5046) WD40_like PF17005.5 EKX33847.1 - 2.1e-05 24.0 0.0 5.8e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 WD40-like domain Nup160 PF11715.8 EKX33847.1 - 7.5e-05 21.6 2.3 0.11 11.1 0.0 4.0 2 2 3 5 5 5 2 Nucleoporin Nup120/160 eIF2A PF08662.11 EKX33847.1 - 0.0028 17.6 0.0 0.038 13.9 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 EKX33847.1 - 0.12 10.9 0.1 0.32 9.5 0.0 1.8 2 0 0 2 2 2 0 Cytochrome D1 heme domain FLgD_tudor PF13861.6 EKX33847.1 - 0.19 12.0 1.3 45 4.4 0.1 4.2 4 0 0 4 4 4 0 FlgD Tudor-like domain Phage_holin_3_7 PF05449.11 EKX33848.1 - 0.031 14.3 1.4 0.096 12.7 1.4 1.8 1 0 0 1 1 1 0 Putative 3TM holin, Phage_holin_3 Phage_holin_3_7 PF05449.11 EKX33849.1 - 0.053 13.5 1.1 0.12 12.4 1.1 1.5 1 0 0 1 1 1 0 Putative 3TM holin, Phage_holin_3 WD40 PF00400.32 EKX33850.1 - 4.9e-09 36.7 9.0 0.0014 19.4 0.1 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX33850.1 - 0.02 15.1 0.1 1.2 9.4 0.0 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 EKX33850.1 - 0.089 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 CPSF A subunit region DUF2368 PF10166.9 EKX33851.1 - 0.058 13.0 0.9 0.11 12.1 0.9 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) AAA_25 PF13481.6 EKX33854.1 - 3.7e-22 78.9 0.0 5.8e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 EKX33854.1 - 1.2e-11 44.4 0.0 1.8e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Toprim_2 PF13155.6 EKX33854.1 - 4e-07 30.4 0.0 1.2e-06 28.8 0.0 1.9 1 0 0 1 1 1 1 Toprim-like AAA_22 PF13401.6 EKX33854.1 - 1.7e-05 25.1 0.0 4.2e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EKX33854.1 - 7e-05 23.3 0.0 0.00014 22.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ATPase PF06745.13 EKX33854.1 - 9e-05 21.9 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 KaiC Toprim_4 PF13662.6 EKX33854.1 - 0.0003 21.2 0.0 0.0039 17.6 0.0 2.4 2 0 0 2 2 2 1 Toprim domain Toprim_3 PF13362.6 EKX33854.1 - 0.00056 20.2 0.0 0.0036 17.6 0.0 2.2 2 1 0 2 2 2 1 Toprim domain NTPase_1 PF03266.15 EKX33854.1 - 0.039 13.9 0.1 0.072 13.0 0.1 1.4 1 0 0 1 1 1 0 NTPase AAA_29 PF13555.6 EKX33854.1 - 0.041 13.6 0.3 0.2 11.4 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SSE PF00437.20 EKX33854.1 - 0.043 12.9 0.0 0.072 12.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 EKX33854.1 - 0.069 12.9 0.1 0.18 11.5 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_tran PF00005.27 EKX33854.1 - 0.086 13.4 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 EKX33854.1 - 0.12 12.7 0.1 0.28 11.6 0.1 1.6 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 EKX33854.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 EKX33854.1 - 0.14 12.1 0.1 0.25 11.3 0.1 1.3 1 0 0 1 1 1 0 NACHT domain SRP54 PF00448.22 EKX33854.1 - 0.17 11.5 0.1 1.4 8.5 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF2075 PF09848.9 EKX33854.1 - 0.17 11.1 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Pyr_redox_2 PF07992.14 EKX33856.1 - 1.6e-25 90.0 0.0 1.8e-25 89.8 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EKX33856.1 - 0.00024 21.6 0.6 0.13 12.8 0.1 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EKX33856.1 - 0.018 15.5 1.4 0.061 13.8 0.0 2.3 1 1 1 2 2 2 0 Putative NAD(P)-binding K_oxygenase PF13434.6 EKX33856.1 - 0.068 12.3 0.1 7.1 5.7 0.0 2.3 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF4147 PF13660.6 EKX33856.1 - 0.13 11.7 0.0 3.8 7.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) Pyr_redox_3 PF13738.6 EKX33856.1 - 0.14 11.4 0.1 2.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Coatomer_E PF04733.14 EKX33857.1 - 3e-05 23.6 0.8 0.083 12.3 0.5 2.3 2 0 0 2 2 2 2 Coatomer epsilon subunit Ribophorin_II PF05817.14 EKX33857.1 - 0.0094 14.6 0.2 0.013 14.1 0.2 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II TPR_19 PF14559.6 EKX33857.1 - 0.018 15.5 0.1 0.044 14.3 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat BUD22 PF09073.10 EKX33857.1 - 0.4 10.0 8.1 0.53 9.6 8.1 1.1 1 0 0 1 1 1 0 BUD22 FAM176 PF14851.6 EKX33857.1 - 0.73 9.5 5.9 0.36 10.5 3.6 1.6 2 0 0 2 2 2 0 FAM176 family RNase_PH PF01138.21 EKX33858.1 - 5.1e-26 91.7 0.1 7.4e-26 91.2 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DnaI_N PF07319.11 EKX33859.1 - 0.079 13.6 0.0 0.12 13.1 0.0 1.2 1 0 0 1 1 1 0 Primosomal protein DnaI N-terminus BicD PF09730.9 EKX33859.1 - 0.11 10.9 0.1 0.14 10.6 0.1 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D zf-H2C2_5 PF13909.6 EKX33860.1 - 0.033 13.9 1.0 0.06 13.1 1.0 1.4 1 0 0 1 1 1 0 C2H2-type zinc-finger domain Pkinase PF00069.25 EKX33861.1 - 1.9e-67 227.5 0.0 2.5e-67 227.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX33861.1 - 1.1e-44 152.7 0.0 1.7e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EKX33861.1 - 2.3e-15 56.7 0.2 6.6e-15 55.2 0.1 1.9 2 0 0 2 2 2 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 EKX33861.1 - 2.3e-05 23.4 0.0 3.7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EKX33861.1 - 6.2e-05 22.5 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EKX33861.1 - 0.0065 15.8 0.0 0.016 14.5 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX33861.1 - 0.0069 16.3 0.0 0.29 11.0 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EKX33861.1 - 0.015 14.3 0.0 0.24 10.3 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain RIO1 PF01163.22 EKX33861.1 - 0.062 12.9 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 RIO1 family PAXX PF15384.6 EKX33862.1 - 0.086 12.5 0.2 0.14 11.9 0.2 1.3 1 0 0 1 1 1 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 Abhydrolase_2 PF02230.16 EKX33864.1 - 5.4e-20 72.1 0.0 5.8e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 EKX33864.1 - 0.0012 18.5 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) AXE1 PF05448.12 EKX33864.1 - 0.12 11.0 0.0 0.53 8.9 0.0 1.8 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 EKX33864.1 - 0.13 11.5 0.0 7.9 5.7 0.0 2.0 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EKX33864.1 - 0.19 11.6 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold SAP PF02037.27 EKX33865.1 - 4.2e-07 29.6 0.2 4.2e-07 29.6 0.2 2.8 3 0 0 3 3 3 1 SAP domain DUF3744 PF12558.8 EKX33865.1 - 0.53 11.1 3.5 0.26 12.1 0.5 2.1 2 1 0 2 2 2 0 ATP-binding cassette cobalt transporter JmjC PF02373.22 EKX33866.1 - 1.6e-08 35.0 0.0 3.7e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 EKX33866.1 - 0.0037 17.0 0.6 0.0071 16.1 0.0 1.7 2 1 0 2 2 2 1 Cupin-like domain Pentapeptide PF00805.22 EKX33868.1 - 5.4e-12 45.1 2.4 7e-06 25.6 0.2 3.3 2 1 1 3 3 3 3 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 EKX33868.1 - 2.5e-11 43.6 1.0 4.9e-08 33.0 0.2 2.8 1 1 2 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 EKX33868.1 - 2.9e-09 36.9 11.6 0.00014 21.9 1.4 3.2 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) FAM104 PF15434.6 EKX33869.1 - 0.094 13.3 3.3 0.098 13.2 0.1 2.4 2 0 0 2 2 2 0 Family 104 FTCD_C PF04961.12 EKX33870.1 - 1.2e-33 116.5 4.9 1.4e-33 116.2 4.9 1.1 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase C_GCAxxG_C_C PF09719.10 EKX33870.1 - 0.0035 17.6 1.2 0.0055 17.0 1.2 1.3 1 0 0 1 1 1 1 Putative redox-active protein (C_GCAxxG_C_C) YtxH PF12732.7 EKX33870.1 - 0.056 14.0 6.4 0.089 13.3 5.6 1.8 1 1 0 1 1 1 0 YtxH-like protein CRISPR_Cas9_WED PF18061.1 EKX33870.1 - 0.13 12.4 0.1 0.2 11.8 0.1 1.2 1 0 0 1 1 1 0 CRISPR-Cas9 WED domain ERM PF00769.19 EKX33870.1 - 0.15 11.9 5.3 0.2 11.4 5.3 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Thioredoxin PF00085.20 EKX33872.1 - 8.3e-19 67.5 0.1 9.4e-19 67.3 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EKX33872.1 - 0.00039 20.8 0.1 0.0021 18.5 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EKX33872.1 - 0.0059 16.9 0.0 0.0089 16.3 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 EKX33872.1 - 0.0079 15.9 0.0 0.0085 15.8 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EKX33872.1 - 0.015 15.2 0.1 0.037 13.9 0.0 1.5 1 1 1 2 2 2 0 AhpC/TSA family DUF2582 PF10771.9 EKX33872.1 - 0.085 13.0 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix domain (DUF2582) Thioredoxin_9 PF14595.6 EKX33872.1 - 0.099 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 EKX33872.1 - 0.16 12.1 0.0 0.27 11.5 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like Skp1_POZ PF03931.15 EKX33873.1 - 7.3e-13 48.5 0.0 1.6e-11 44.2 0.0 2.0 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.31 EKX33873.1 - 0.00073 19.7 0.6 0.001 19.3 0.6 1.4 1 1 0 1 1 1 1 BTB/POZ domain Yae1_N PF09811.9 EKX33874.1 - 0.041 13.6 0.1 4 7.2 0.0 2.2 2 0 0 2 2 2 0 Essential protein Yae1, N terminal SNF2_N PF00176.23 EKX33876.1 - 8.9e-58 195.7 0.0 2.7e-57 194.1 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX33876.1 - 1.4e-20 73.7 0.9 3.9e-20 72.2 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.24 EKX33876.1 - 8.9e-20 70.4 5.3 3.5e-13 49.2 0.3 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 EKX33876.1 - 2.6e-10 40.6 0.0 1.9e-09 37.7 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EKX33876.1 - 4.1e-07 29.4 0.1 2.2e-06 27.1 0.0 2.1 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 EKX33876.1 - 0.0052 16.6 0.0 0.01 15.6 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 EKX33876.1 - 0.018 14.3 0.1 0.065 12.5 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF1308 PF07000.11 EKX33876.1 - 0.03 14.2 0.0 0.082 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) AAA_34 PF13872.6 EKX33876.1 - 0.079 11.8 0.1 0.19 10.6 0.1 1.6 1 1 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 AAA_22 PF13401.6 EKX33876.1 - 0.082 13.2 0.0 0.74 10.1 0.0 2.6 1 1 0 1 1 1 0 AAA domain CIMR PF00878.18 EKX33877.1 - 4.7e-07 30.0 1.2 0.032 14.3 0.0 2.9 2 1 1 3 3 3 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.10 EKX33877.1 - 2.8e-06 27.4 0.7 1.4e-05 25.1 0.7 1.9 1 1 0 1 1 1 1 Autophagy-related protein 27 PDZ PF00595.24 EKX33878.1 - 4.1e-15 55.9 0.1 5.1e-08 33.2 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EKX33878.1 - 1.5e-12 47.2 0.0 1.6e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX33878.1 - 2e-10 40.8 0.0 9.3e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 PDZ domain TPR_10 PF13374.6 EKX33879.1 - 0.077 12.9 0.2 0.2 11.6 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat UPF0242 PF06785.11 EKX33881.1 - 0.047 13.8 9.5 0.063 13.4 9.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PTA_PTB PF01515.19 EKX33881.1 - 0.11 11.8 2.2 0.23 10.7 2.1 1.6 1 1 0 1 1 1 0 Phosphate acetyl/butaryl transferase DUF1947 PF09183.10 EKX33881.1 - 0.14 12.5 1.9 0.33 11.3 1.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) Selenoprotein_S PF06936.11 EKX33881.1 - 0.26 11.1 11.2 0.46 10.3 11.2 1.4 1 1 0 1 1 1 0 Selenoprotein S (SelS) O-antigen_lig PF13425.6 EKX33881.1 - 1.1 8.0 4.6 1.5 7.6 4.6 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF5401 PF17380.2 EKX33881.1 - 4.7 5.2 16.3 6.1 4.8 16.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Nnf1 PF03980.14 EKX33882.1 - 1.1e-11 45.0 0.3 2.6e-11 43.9 0.2 1.7 2 0 0 2 2 2 1 Nnf1 HrpB7 PF09486.10 EKX33882.1 - 0.047 14.1 2.3 0.047 14.1 2.3 1.6 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) CLZ PF16526.5 EKX33882.1 - 0.11 12.9 7.3 0.19 12.1 2.9 2.7 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GAS PF13851.6 EKX33882.1 - 0.2 11.0 5.1 0.061 12.7 1.5 1.9 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding FHA PF00498.26 EKX33883.1 - 1.1e-13 51.3 0.0 2.3e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 FHA domain WD40 PF00400.32 EKX33883.1 - 3.3e-11 43.5 7.3 0.27 12.2 0.1 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat HELP PF03451.14 EKX33883.1 - 7.1e-08 32.2 0.0 1.8e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 HELP motif Yop-YscD_cpl PF16697.5 EKX33883.1 - 1.7e-05 25.0 0.0 6.3e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FBPase_glpX PF03320.13 EKX33885.1 - 0.11 11.3 0.0 0.12 11.2 0.0 1.0 1 0 0 1 1 1 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded BAR PF03114.18 EKX33886.1 - 0.00015 21.5 0.0 0.00018 21.2 0.0 1.1 1 0 0 1 1 1 1 BAR domain PITH PF06201.13 EKX33888.1 - 3.3e-36 124.8 0.3 4.1e-36 124.5 0.3 1.1 1 0 0 1 1 1 1 PITH domain RWP-RK PF02042.15 EKX33889.1 - 2.7e-14 52.9 0.0 5.5e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain HTH_Mga PF08280.11 EKX33889.1 - 0.16 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain DUF3613 PF12266.8 EKX33889.1 - 0.22 11.3 2.2 0.38 10.6 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3613) FXMRP1_C_core PF12235.8 EKX33889.1 - 0.46 11.1 7.0 0.48 11.1 3.5 2.1 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal MORN PF02493.20 EKX33890.1 - 2.8e-52 171.6 59.4 1.3e-06 28.0 3.7 8.5 9 0 0 9 9 9 8 MORN repeat DUF3048_C PF17479.2 EKX33890.1 - 0.003 17.9 13.5 2.1 8.8 0.1 4.8 1 1 4 5 5 5 3 Protein of unknown function (DUF3048) C-terminal domain DUF448 PF04296.13 EKX33890.1 - 6.9 6.6 5.2 11 5.9 0.3 3.0 2 2 1 3 3 3 0 Protein of unknown function (DUF448) DUF4072 PF13284.6 EKX33891.1 - 3.4 8.2 4.9 2.9e+02 2.0 0.1 4.8 1 1 3 5 5 5 0 Domain of unknown function (DUF4072) C2 PF00168.30 EKX33892.1 - 1.3e-15 57.6 0.2 1.4e-15 57.4 0.2 1.0 1 0 0 1 1 1 1 C2 domain FSA_C PF10479.9 EKX33893.1 - 1.7 6.7 6.0 2.4 6.2 6.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Shadoo PF14999.6 EKX33894.1 - 9.7 6.3 8.9 24 5.0 8.9 1.6 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective LDcluster4 PF18306.1 EKX33895.1 - 0.12 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 SLOG cluster4 family ABC2_membrane PF01061.24 EKX33896.1 - 8.3e-60 201.8 60.9 1.1e-33 116.4 21.3 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EKX33896.1 - 2.5e-38 131.7 0.0 9.9e-21 74.7 0.0 3.0 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 EKX33896.1 - 4.5e-07 30.0 0.0 0.0011 18.9 0.0 3.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EKX33896.1 - 1.3e-06 28.9 1.2 0.0081 16.6 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 EKX33896.1 - 3.3e-06 26.7 0.2 0.0057 16.4 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EKX33896.1 - 4.3e-06 26.7 0.2 0.0014 18.5 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 EKX33896.1 - 4.7e-06 26.8 0.1 0.07 13.3 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 EKX33896.1 - 9e-06 26.0 0.0 0.017 15.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EKX33896.1 - 6e-05 22.7 0.1 0.13 11.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 EKX33896.1 - 0.00015 22.2 0.1 0.44 11.0 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EKX33896.1 - 0.00048 20.1 0.3 0.6 10.1 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EKX33896.1 - 0.00052 19.8 0.1 0.37 10.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain PDR_assoc PF08370.11 EKX33896.1 - 0.00067 19.4 1.4 0.048 13.4 0.0 2.9 2 0 0 2 2 2 1 Plant PDR ABC transporter associated AAA_18 PF13238.6 EKX33896.1 - 0.00082 19.9 0.0 0.41 11.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EKX33896.1 - 0.0016 18.4 0.6 1.6 8.6 0.0 2.9 3 0 0 3 3 2 2 NACHT domain ATPase_2 PF01637.18 EKX33896.1 - 0.0021 18.0 0.0 0.12 12.3 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea cobW PF02492.19 EKX33896.1 - 0.0022 17.6 0.3 1 8.9 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 EKX33896.1 - 0.0051 17.2 0.0 0.78 10.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.6 EKX33896.1 - 0.0051 16.8 0.0 0.27 11.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.6 EKX33896.1 - 0.0052 17.1 0.1 1.4 9.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EKX33896.1 - 0.0061 16.5 0.9 0.39 10.6 0.0 3.0 3 0 0 3 3 3 1 NTPase AAA_24 PF13479.6 EKX33896.1 - 0.012 15.4 0.4 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EKX33896.1 - 0.012 15.6 0.3 8.1 6.6 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.19 EKX33896.1 - 0.019 14.4 0.0 0.99 8.8 0.0 2.6 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 EKX33896.1 - 0.02 15.1 0.1 7.3 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 EKX33896.1 - 0.021 14.6 0.1 3.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_23 PF13476.6 EKX33896.1 - 0.021 15.3 0.1 0.71 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EKX33896.1 - 0.071 12.9 0.4 4.8 6.9 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DnaB_C PF03796.15 EKX33896.1 - 0.1 11.9 0.0 0.89 8.8 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Roc PF08477.13 EKX33896.1 - 0.18 12.1 0.1 32 4.7 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ABC2_membrane_3 PF12698.7 EKX33896.1 - 8.6 5.4 49.1 0.049 12.7 17.7 2.4 2 0 0 2 2 2 0 ABC-2 family transporter protein Arylsulfotran_N PF17425.2 EKX33897.1 - 0.03 14.4 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Arylsulfotransferase Ig-like domain DUF3228 PF11539.8 EKX33898.1 - 9.3e-36 123.2 0.0 1e-35 123.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) MDMPI_N PF11716.8 EKX33900.1 - 3.5 8.3 9.7 12 6.6 0.9 2.7 1 1 1 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain DUF2188 PF09954.9 EKX33902.1 - 0.31 11.2 6.3 14 6.0 0.1 5.0 4 2 1 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2188) ERGIC_N PF13850.6 EKX33903.1 - 0.16 12.3 1.0 0.32 11.4 0.9 1.7 1 1 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) RF-1 PF00472.20 EKX33906.1 - 6.1e-22 77.7 5.8 8.3e-22 77.3 5.8 1.1 1 0 0 1 1 1 1 RF-1 domain DUF2201_N PF13203.6 EKX33906.1 - 0.31 10.6 3.4 0.39 10.3 3.4 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain HTH_38 PF13936.6 EKX33907.1 - 0.05 13.4 0.7 0.12 12.2 0.7 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain CENP-B_N PF04218.13 EKX33907.1 - 0.16 11.6 0.2 0.41 10.3 0.2 1.7 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Cep57_CLD_2 PF14197.6 EKX33908.1 - 0.059 13.5 3.1 0.68 10.1 0.3 2.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 YabA PF06156.13 EKX33908.1 - 0.091 13.4 3.0 0.35 11.5 3.0 2.1 1 1 0 1 1 1 0 Initiation control protein YabA DUF1514 PF07438.11 EKX33908.1 - 0.27 11.1 3.7 12 5.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) DUF4407 PF14362.6 EKX33908.1 - 0.33 10.3 1.8 0.4 10.0 1.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) BK_channel_a PF03493.18 EKX33910.1 - 1.8e-29 101.8 0.0 2.7e-28 98.0 0.0 2.4 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 EKX33910.1 - 1.1e-11 44.5 2.3 3.7e-11 42.8 2.3 2.0 1 0 0 1 1 1 1 Ion channel TrkA_N PF02254.18 EKX33910.1 - 0.0078 16.5 0.0 1.5 9.1 0.0 2.6 2 0 0 2 2 2 2 TrkA-N domain MARVEL PF01284.23 EKX33910.1 - 0.039 14.0 5.5 2.3 8.3 0.1 2.9 2 1 0 2 2 2 0 Membrane-associating domain LSM PF01423.22 EKX33911.1 - 1.4e-15 56.7 0.1 2e-15 56.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EKX33911.1 - 0.012 15.7 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Feld-I_B PF09252.10 EKX33911.1 - 0.072 13.1 0.0 0.1 12.6 0.0 1.1 1 0 0 1 1 1 0 Allergen Fel d I-B chain GRP PF07172.11 EKX33911.1 - 6.7 7.5 27.4 9.4 7.0 27.4 1.2 1 0 0 1 1 1 0 Glycine rich protein family MMS1_N PF10433.9 EKX33915.1 - 4.5e-105 352.1 0.0 1.6e-104 350.2 0.0 1.9 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EKX33915.1 - 3.6e-81 273.0 0.1 1.1e-80 271.3 0.0 1.9 2 0 0 2 2 2 1 CPSF A subunit region Complex1_LYR PF05347.15 EKX33916.1 - 2.6e-07 30.6 2.6 4.5e-07 29.8 2.6 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EKX33916.1 - 0.01 16.5 1.2 0.011 16.4 1.2 1.1 1 0 0 1 1 1 0 Complex1_LYR-like TetR_C_24 PF17932.1 EKX33916.1 - 0.053 13.8 0.6 0.067 13.5 0.5 1.3 1 1 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Metal_resist PF13801.6 EKX33916.1 - 0.47 10.7 6.4 0.64 10.2 6.4 1.2 1 0 0 1 1 1 0 Heavy-metal resistance DUF3431 PF11913.8 EKX33917.1 - 6.6e-20 71.8 0.4 1.7e-10 41.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3431) REJ PF02010.15 EKX33918.1 - 4.1e-39 134.6 5.0 3.6e-30 105.2 0.8 2.6 2 0 0 2 2 2 2 REJ domain EGF_2 PF07974.13 EKX33918.1 - 9.9e-05 22.6 6.4 9.9e-05 22.6 6.4 4.5 3 1 1 4 4 4 1 EGF-like domain DUF5527 PF17665.1 EKX33918.1 - 0.08 12.5 2.7 0.45 10.1 0.4 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5527) RCC1 PF00415.18 EKX33919.1 - 2.8e-67 223.2 11.3 2.1e-11 44.3 0.3 8.3 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX33919.1 - 1.1e-33 114.3 35.4 8.1e-09 35.1 0.6 8.0 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat EGF_2 PF07974.13 EKX33919.1 - 4.9e-16 58.8 134.0 0.00059 20.1 9.4 8.1 7 1 1 8 8 8 7 EGF-like domain EGF PF00008.27 EKX33919.1 - 0.00031 21.0 103.8 0.005 17.1 7.5 8.5 7 1 0 7 7 7 4 EGF-like domain PGM_PMM_I PF02878.16 EKX33920.1 - 3.4e-34 117.5 0.0 6.2e-34 116.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EKX33920.1 - 9.5e-21 74.1 0.1 1.8e-20 73.2 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EKX33920.1 - 7.3e-20 71.5 0.0 1.7e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EKX33920.1 - 2.3e-06 27.7 0.0 5.2e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Ank_2 PF12796.7 EKX33921.1 - 2.9e-15 56.6 0.7 1.1e-07 32.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX33921.1 - 2.1e-12 47.3 2.8 6.6e-06 26.6 0.0 4.0 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX33921.1 - 2.6e-08 34.0 0.7 0.12 12.7 0.0 5.0 4 1 1 5 5 5 2 Ankyrin repeats (many copies) ART PF01129.18 EKX33921.1 - 1e-07 31.5 0.0 4e-07 29.6 0.0 1.8 1 1 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase ADPrib_exo_Tox PF03496.14 EKX33921.1 - 2.5e-06 27.0 0.0 7.4e-06 25.4 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosyltransferase exoenzyme Ank_3 PF13606.6 EKX33921.1 - 0.00031 20.9 0.5 16 6.5 0.0 5.1 5 0 0 5 5 5 1 Ankyrin repeat DivIC PF04977.15 EKX33921.1 - 0.11 12.3 0.3 0.27 11.1 0.3 1.6 1 0 0 1 1 1 0 Septum formation initiator BDHCT PF08072.11 EKX33921.1 - 8.9 6.5 10.0 43 4.3 0.2 4.5 4 0 0 4 4 4 0 BDHCT (NUC031) domain AAA_11 PF13086.6 EKX33922.1 - 0.044 13.6 0.5 0.69 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain MbeB_N PF04837.12 EKX33922.1 - 4.4 7.7 6.1 1.6 9.1 2.4 2.4 2 0 0 2 2 2 0 MbeB-like, N-term conserved region RVT_1 PF00078.27 EKX33924.1 - 1.8e-08 34.2 0.1 3.4e-08 33.3 0.1 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CK2S PF15011.6 EKX33925.1 - 0.06 13.2 0.0 0.069 13.0 0.0 1.1 1 0 0 1 1 1 0 Casein Kinase 2 substrate adh_short PF00106.25 EKX33929.1 - 1.8e-17 63.5 0.1 1.2e-16 60.8 0.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EKX33929.1 - 1.4e-16 60.8 0.0 1e-15 58.0 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX33929.1 - 0.11 12.4 0.7 1.3 8.9 0.7 2.2 1 1 0 1 1 1 0 KR domain Exo_endo_phos PF03372.23 EKX33930.1 - 5.7e-23 81.7 0.0 9.8e-23 80.9 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family E1_DerP2_DerF2 PF02221.15 EKX33931.1 - 7.3e-17 62.1 0.1 8.6e-17 61.8 0.1 1.1 1 0 0 1 1 1 1 ML domain Alpha_kinase PF02816.18 EKX33932.1 - 1.6e-47 162.0 0.4 1e-46 159.4 0.4 2.0 1 1 0 1 1 1 1 Alpha-kinase family ORC_WH_C PF18137.1 EKX33933.1 - 0.016 15.3 1.0 0.027 14.5 0.2 1.8 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal Alpha_kinase PF02816.18 EKX33934.1 - 5.7e-43 147.2 0.0 7.5e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family DUF726 PF05277.12 EKX33935.1 - 6e-57 193.1 0.0 7e-57 192.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF726) FYVE PF01363.21 EKX33939.1 - 1.1e-15 57.5 6.3 2e-15 56.7 6.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 EKX33939.1 - 0.0086 16.3 2.5 0.019 15.1 2.5 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger SopA_C PF13979.6 EKX33939.1 - 0.021 14.5 0.1 4.9 6.9 0.0 2.2 2 0 0 2 2 2 0 SopA-like catalytic domain zf-B_box PF00643.24 EKX33939.1 - 0.14 12.3 5.3 0.12 12.5 1.5 2.3 2 0 0 2 2 2 0 B-box zinc finger AMPK1_CBM PF16561.5 EKX33940.1 - 4.1e-09 36.5 0.7 7.7e-09 35.7 0.7 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase SusF_SusE PF16411.5 EKX33940.1 - 0.04 14.4 0.4 0.066 13.7 0.4 1.5 1 1 0 1 1 1 0 Outer membrane protein SusF_SusE PPR_2 PF13041.6 EKX33941.1 - 4.3e-19 68.5 0.1 2.3e-09 37.3 0.0 4.6 2 1 2 4 4 4 3 PPR repeat family Methyltransf_4 PF02390.17 EKX33941.1 - 2.1e-15 56.6 0.0 4e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase PPR PF01535.20 EKX33941.1 - 6.5e-15 54.3 3.8 0.00067 19.7 0.1 5.2 5 0 0 5 5 5 3 PPR repeat PPR_1 PF12854.7 EKX33941.1 - 2.4e-10 39.9 0.0 0.0072 16.0 0.0 4.5 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.6 EKX33941.1 - 3.6e-06 26.9 0.0 0.31 11.2 0.0 3.4 2 1 1 3 3 3 2 Pentatricopeptide repeat domain PPR_long PF17177.4 EKX33941.1 - 0.00017 21.0 0.0 0.22 10.8 0.0 2.2 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP BTAD PF03704.17 EKX33941.1 - 0.0021 18.5 3.4 0.06 13.8 0.1 3.2 2 1 1 3 3 3 1 Bacterial transcriptional activator domain TPR_19 PF14559.6 EKX33941.1 - 1 9.9 4.8 4.4 7.9 0.1 3.8 4 1 1 5 5 5 0 Tetratricopeptide repeat Prefoldin_2 PF01920.20 EKX33942.1 - 1.7e-05 24.7 0.0 4.3e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Prefoldin subunit RWP-RK PF02042.15 EKX33943.1 - 1.5e-10 40.8 0.0 3e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_23 PF13384.6 EKX33943.1 - 0.018 14.8 0.1 0.035 13.9 0.1 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_8 PF02954.19 EKX33943.1 - 0.039 13.7 0.1 0.099 12.4 0.1 1.7 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family Sigma70_r4_2 PF08281.12 EKX33943.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_17 PF12728.7 EKX33943.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain KHA PF11834.8 EKX33943.1 - 0.14 12.3 0.2 0.89 9.7 0.0 2.2 2 0 0 2 2 2 0 KHA, dimerisation domain of potassium ion channel zf-CDGSH PF09360.10 EKX33944.1 - 2.4e-20 72.5 4.5 3e-11 43.4 0.4 2.2 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type CDC48_2 PF02933.17 EKX33945.1 - 0.0031 17.3 0.1 0.0036 17.1 0.1 1.2 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 PDZ PF00595.24 EKX33945.1 - 0.006 16.9 0.0 0.0083 16.5 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX33945.1 - 0.011 15.6 0.1 0.02 14.7 0.1 1.5 1 0 0 1 1 1 0 PDZ domain PFEMP PF03011.15 EKX33946.1 - 0.9 10.2 3.9 25 5.5 0.2 2.6 2 1 0 2 2 2 0 PFEMP DBL domain FAM220 PF15487.6 EKX33946.1 - 1 8.9 7.4 0.17 11.5 3.4 1.6 2 0 0 2 2 2 0 FAM220 family DUF2681 PF10883.8 EKX33946.1 - 2 8.9 7.1 0.72 10.3 1.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) OAD_gamma PF04277.13 EKX33946.1 - 9.2 6.9 12.3 30 5.3 12.3 2.0 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DAO PF01266.24 EKX33948.1 - 3.5e-07 30.1 0.2 4.4e-07 29.8 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase RXT2_N PF08595.11 EKX33948.1 - 0.14 12.1 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 EKX33949.1 - 1.7e-24 86.0 12.8 1.5e-20 72.9 11.7 2.6 1 1 0 2 2 2 2 DNA polymerase phi TPR_19 PF14559.6 EKX33950.1 - 1.1e-17 64.2 6.6 0.0031 18.0 1.1 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 EKX33950.1 - 2.7e-17 62.8 11.1 1.2e-09 38.3 0.5 5.2 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX33950.1 - 5.3e-17 60.5 1.4 0.0063 16.6 0.1 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX33950.1 - 1.5e-16 59.4 10.8 0.004 16.9 0.0 8.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX33950.1 - 2e-14 52.5 8.8 0.0024 17.9 0.0 7.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX33950.1 - 6.8e-12 45.8 17.6 0.0034 18.0 0.5 5.3 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 EKX33950.1 - 8.5e-12 44.2 2.9 0.0085 16.0 0.1 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EKX33950.1 - 2.5e-11 43.1 7.9 0.0042 17.4 0.0 6.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX33950.1 - 1.7e-09 37.7 17.7 0.68 10.9 0.1 8.5 3 3 5 8 8 8 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX33950.1 - 2.8e-06 27.0 17.2 0.0034 17.2 1.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX33950.1 - 0.00051 19.7 12.5 0.053 13.2 0.2 5.3 6 0 0 6 6 6 2 TPR repeat TPR_9 PF13371.6 EKX33950.1 - 0.001 19.2 11.6 0.087 13.0 0.2 5.1 4 2 1 5 5 5 2 Tetratricopeptide repeat DUF5112 PF17139.4 EKX33950.1 - 0.048 13.1 2.9 0.23 10.9 0.7 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5112) Ribosomal_L7Ae PF01248.26 EKX33951.1 - 1.2e-26 92.2 1.5 1.5e-26 92.0 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 EKX33951.1 - 0.0023 17.8 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain BST2 PF16716.5 EKX33952.1 - 0.00052 20.5 0.8 0.00052 20.5 0.8 6.8 6 1 1 7 7 7 2 Bone marrow stromal antigen 2 PDZ PF00595.24 EKX33952.1 - 0.015 15.6 0.3 0.043 14.2 0.3 1.7 1 0 0 1 1 1 0 PDZ domain NOA36 PF06524.12 EKX33952.1 - 8.3 5.6 15.4 31 3.8 15.4 1.9 1 0 0 1 1 1 0 NOA36 protein PDZ_6 PF17820.1 EKX33953.1 - 2.1e-10 40.3 0.0 5.1e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Peptidase_S41 PF03572.18 EKX33953.1 - 7.7e-08 32.1 0.1 1.6e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 Peptidase family S41 PDZ_2 PF13180.6 EKX33953.1 - 3.2e-07 30.6 0.1 7.2e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX33953.1 - 3.2e-07 30.6 0.1 8.1e-07 29.3 0.1 1.7 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX33953.1 - 0.0017 18.3 0.1 0.0044 16.9 0.1 1.7 1 0 0 1 1 1 1 Tricorn protease PDZ domain LysM PF01476.20 EKX33954.1 - 0.012 15.7 0.1 0.64 10.1 0.1 2.6 2 1 0 2 2 2 0 LysM domain DUF3237 PF11578.8 EKX33955.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3237) D123 PF07065.14 EKX33956.1 - 2.2e-18 66.5 1.0 6.2e-18 65.0 0.2 2.1 2 0 0 2 2 2 1 D123 EF-hand_7 PF13499.6 EKX33956.1 - 1.9e-07 31.4 4.2 0.017 15.5 0.1 4.4 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX33956.1 - 3.5e-06 26.2 0.1 0.092 12.3 0.0 4.2 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 EKX33956.1 - 4.1e-06 26.5 0.2 0.059 13.2 0.0 3.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX33956.1 - 0.00023 20.8 2.4 0.32 11.0 0.0 4.2 5 0 0 5 5 5 2 EF-hand domain PA PF02225.22 EKX33956.1 - 0.00055 19.9 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 PA domain EF-hand_5 PF13202.6 EKX33956.1 - 0.022 14.2 0.0 23 4.7 0.0 3.7 3 0 0 3 3 3 0 EF hand DDA1 PF10172.9 EKX33956.1 - 0.025 14.8 0.0 3.1 8.2 0.0 2.9 2 0 0 2 2 2 0 Det1 complexing ubiquitin ligase EF-hand_10 PF14788.6 EKX33956.1 - 0.037 13.9 0.2 0.17 11.8 0.1 2.2 2 0 0 2 2 2 0 EF hand NPA PF16469.5 EKX33956.1 - 0.23 12.0 3.1 0.25 11.9 0.2 2.7 2 0 0 2 2 2 0 Nematode polyprotein allergen ABA-1 C2 PF00168.30 EKX33957.1 - 1.3e-11 44.6 0.0 2.5e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain AAA_6 PF12774.7 EKX33958.1 - 4.5e-157 522.1 0.0 3.1e-156 519.4 0.0 2.4 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EKX33958.1 - 5e-131 437.5 4.9 5e-131 437.5 4.9 3.8 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EKX33958.1 - 4.3e-100 334.3 0.0 2.9e-99 331.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EKX33958.1 - 4.3e-86 287.6 1.9 4.3e-86 287.6 1.9 3.8 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 EKX33958.1 - 1.7e-78 262.3 0.4 7.6e-74 247.1 0.0 3.7 3 0 0 3 3 3 1 P-loop containing dynein motor region MT PF12777.7 EKX33958.1 - 5.2e-47 160.5 10.3 9.5e-47 159.7 10.3 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EKX33958.1 - 1.2e-45 154.4 0.0 1.9e-42 144.1 0.0 3.3 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EKX33958.1 - 3.7e-30 104.7 0.3 1.5e-29 102.7 0.3 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EKX33958.1 - 9.2e-23 80.4 0.3 5.3e-22 77.9 0.0 2.6 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 EKX33958.1 - 2.2e-19 69.8 0.0 2.3e-07 30.9 0.0 6.1 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EKX33958.1 - 3.8e-06 27.2 0.7 0.94 9.8 0.0 4.6 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 EKX33958.1 - 1.6e-05 25.3 0.6 6.6 7.2 0.0 4.9 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX33958.1 - 0.00013 22.4 0.5 1.8 8.9 0.0 5.0 5 0 0 5 5 4 1 AAA ATPase domain AAA_18 PF13238.6 EKX33958.1 - 0.0037 17.8 0.0 0.074 13.6 0.0 3.3 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EKX33958.1 - 0.022 14.5 0.6 2.1 8.0 0.0 3.8 4 0 0 4 4 4 0 Sigma-54 interaction domain RNA_helicase PF00910.22 EKX33958.1 - 0.025 15.0 0.1 12 6.3 0.0 3.7 3 0 0 3 3 3 0 RNA helicase DEAD PF00270.29 EKX33958.1 - 0.026 14.3 0.0 7.6 6.3 0.0 3.7 3 1 0 3 3 3 0 DEAD/DEAH box helicase DUF853 PF05872.12 EKX33958.1 - 0.036 12.7 3.2 4.1 5.9 0.1 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) T2SSE PF00437.20 EKX33958.1 - 0.039 13.0 3.1 3.6 6.6 0.0 3.6 4 0 0 4 4 4 0 Type II/IV secretion system protein AAA_24 PF13479.6 EKX33958.1 - 0.047 13.4 0.9 1.1 9.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 EKX33958.1 - 0.067 12.6 0.9 1.2 8.5 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 EKX33958.1 - 0.51 9.7 2.9 14 5.0 0.0 3.5 4 0 0 4 4 3 0 FtsK/SpoIIIE family AAA_30 PF13604.6 EKX33958.1 - 0.85 9.3 4.6 10 5.8 0.3 3.3 3 0 0 3 3 3 0 AAA domain ATPase PF06745.13 EKX33958.1 - 1.3 8.3 7.2 0.53 9.6 0.0 3.5 3 0 0 3 3 2 0 KaiC ResIII PF04851.15 EKX33958.1 - 1.6 8.7 6.0 3.3 7.7 0.0 3.6 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit Sec8_exocyst PF04048.14 EKX33958.1 - 2.8 7.8 13.2 9.1 6.2 1.2 5.0 4 0 0 4 4 4 0 Sec8 exocyst complex component specific domain AATF-Che1 PF13339.6 EKX33958.1 - 4.5 8.0 19.2 2.5 8.8 0.1 5.4 5 1 0 5 5 4 0 Apoptosis antagonizing transcription factor Sulfotransfer_1 PF00685.27 EKX33960.1 - 0.00053 19.6 0.0 0.0017 17.9 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_1 PF00685.27 EKX33961.1 - 2.5e-18 66.5 1.1 5.9e-18 65.3 1.1 1.6 1 1 0 1 1 1 1 Sulfotransferase domain DUF3911 PF13050.6 EKX33961.1 - 0.0085 16.2 0.3 0.014 15.5 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3911) PI3K_P85_iSH2 PF16454.5 EKX33962.1 - 0.0016 18.1 0.2 0.0024 17.5 0.2 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Bestrophin PF01062.21 EKX33963.1 - 0.19 11.1 0.4 0.23 10.8 0.4 1.2 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel C2 PF00168.30 EKX33964.1 - 8.8e-14 51.6 0.0 1.9e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain Arm PF00514.23 EKX33964.1 - 0.061 13.4 0.1 0.51 10.5 0.1 2.8 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat Amino_oxidase PF01593.24 EKX33965.1 - 5.8e-15 55.5 0.2 9.2e-15 54.9 0.2 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EKX33965.1 - 2.5e-13 50.0 0.1 2.5e-13 50.0 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EKX33965.1 - 4.8e-11 42.4 5.1 4.1e-06 26.3 0.8 1.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EKX33965.1 - 4.8e-06 26.0 0.4 8.1e-06 25.3 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EKX33965.1 - 2e-05 23.9 2.2 3.1e-05 23.2 2.2 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 EKX33965.1 - 3.8e-05 23.1 0.5 6.8e-05 22.3 0.5 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 EKX33965.1 - 0.00011 21.9 0.6 0.00022 20.9 0.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EKX33965.1 - 0.00014 20.7 0.8 0.00023 20.0 0.8 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 EKX33965.1 - 0.00055 20.4 1.2 0.0016 19.0 1.0 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EKX33965.1 - 0.0012 18.2 0.3 0.0012 18.2 0.3 1.6 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 EKX33965.1 - 0.0021 17.5 1.5 0.004 16.6 1.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EKX33965.1 - 0.0089 15.1 0.9 0.013 14.6 0.9 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EKX33965.1 - 0.015 14.6 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.12 EKX33965.1 - 0.051 13.1 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Lycopene_cycl PF05834.12 EKX33965.1 - 0.053 12.6 0.1 0.073 12.1 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 EKX33965.1 - 0.08 13.4 0.1 0.19 12.2 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Trp_halogenase PF04820.14 EKX33965.1 - 0.099 11.5 0.2 0.13 11.1 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase YjeF_N PF03853.15 EKX33965.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus Amino_oxidase PF01593.24 EKX33966.1 - 6.4e-20 71.9 0.0 9e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Tudor_4 PF18358.1 EKX33966.1 - 0.0041 16.7 0.1 0.0084 15.7 0.1 1.5 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain Agenet PF05641.12 EKX33966.1 - 0.0053 17.2 2.0 0.0061 17.0 0.2 1.9 2 0 0 2 2 2 1 Agenet domain Prenylcys_lyase PF07156.14 EKX33966.1 - 0.0068 15.6 0.0 0.0092 15.1 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase SCA7 PF08313.12 EKX33967.1 - 9.5e-18 63.9 0.2 9.5e-18 63.9 0.2 1.8 2 0 0 2 2 2 1 SCA7, zinc-binding domain ZZ PF00569.17 EKX33967.1 - 5e-10 39.0 3.3 5e-10 39.0 3.3 2.2 2 0 0 2 2 2 1 Zinc finger, ZZ type C1_2 PF03107.16 EKX33967.1 - 0.0019 18.5 4.9 0.0019 18.5 4.9 2.0 2 0 0 2 2 2 1 C1 domain Sgf11 PF08209.11 EKX33967.1 - 0.0077 15.8 0.9 0.0077 15.8 0.9 2.9 2 1 1 3 3 3 1 Sgf11 (transcriptional regulation protein) DUF4023 PF13215.6 EKX33967.1 - 0.85 9.7 5.8 0.25 11.4 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4023) Nop14 PF04147.12 EKX33968.1 - 0.4 8.8 41.5 0.47 8.6 41.5 1.0 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 EKX33968.1 - 0.46 8.9 35.8 0.55 8.6 35.8 1.1 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.14 EKX33968.1 - 0.58 8.4 36.6 0.82 7.9 36.6 1.3 1 0 0 1 1 1 0 CDC45-like protein CCSAP PF15748.5 EKX33968.1 - 0.66 10.1 20.5 0.77 9.9 20.5 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Presenilin PF01080.17 EKX33968.1 - 1.2 7.8 26.4 1.4 7.6 26.4 1.0 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 EKX33968.1 - 1.9 8.2 20.9 2.2 8.0 20.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.12 EKX33968.1 - 3 7.2 39.5 3.5 7.0 39.5 1.1 1 0 0 1 1 1 0 SDA1 Spore_coat_CotO PF14153.6 EKX33968.1 - 4.6 7.1 24.6 6.1 6.7 24.6 1.4 1 0 0 1 1 1 0 Spore coat protein CotO TFIIF_alpha PF05793.12 EKX33968.1 - 4.6 5.7 34.1 4.7 5.7 34.1 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PPP4R2 PF09184.11 EKX33968.1 - 6 6.4 32.6 7.8 6.0 32.6 1.3 1 0 0 1 1 1 0 PPP4R2 MCM_bind PF09739.9 EKX33968.1 - 6.2 5.1 17.4 7.6 4.9 17.4 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Thioredoxin PF00085.20 EKX33969.1 - 5.5e-21 74.5 0.1 6.5e-21 74.3 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EKX33969.1 - 9.1e-05 22.7 0.0 0.0012 19.1 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 EKX33969.1 - 0.00011 21.6 0.3 0.00013 21.4 0.3 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 EKX33969.1 - 0.00018 21.2 0.0 0.00022 21.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin EF-hand_5 PF13202.6 EKX33969.1 - 0.00033 20.0 0.0 0.001 18.5 0.0 1.8 2 0 0 2 2 2 1 EF hand Thioredoxin_2 PF13098.6 EKX33969.1 - 0.00069 20.0 0.2 0.0029 18.0 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain EF-hand_1 PF00036.32 EKX33969.1 - 0.00074 18.9 0.1 0.00074 18.9 0.1 2.4 3 0 0 3 3 3 1 EF hand AhpC-TSA PF00578.21 EKX33969.1 - 0.003 17.5 0.0 0.004 17.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family EF-hand_8 PF13833.6 EKX33969.1 - 0.0032 17.3 3.4 0.0093 15.8 0.1 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX33969.1 - 0.0059 16.4 0.0 0.019 14.9 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain Thioredoxin_7 PF13899.6 EKX33969.1 - 0.0084 16.3 0.3 0.012 15.7 0.3 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_6 PF13848.6 EKX33969.1 - 0.014 15.4 0.0 0.22 11.4 0.0 1.8 1 1 1 2 2 2 0 Thioredoxin-like domain EF-hand_7 PF13499.6 EKX33969.1 - 0.073 13.5 0.1 0.22 12.0 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain pair TraF PF13728.6 EKX33969.1 - 0.15 11.8 0.1 0.24 11.2 0.1 1.3 1 1 0 1 1 1 0 F plasmid transfer operon protein Myb_DNA-binding PF00249.31 EKX33970.1 - 5.4e-09 36.1 0.0 6.4e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EKX33970.1 - 0.00049 19.9 0.0 0.0015 18.4 0.0 1.6 1 1 1 2 2 2 1 Myb DNA-binding like Trep_dent_lipo PF09710.10 EKX33970.1 - 0.066 12.1 0.0 0.07 12.1 0.0 1.0 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) Ank_2 PF12796.7 EKX33971.1 - 9e-27 93.5 2.9 2.5e-13 50.4 0.5 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX33971.1 - 3.7e-26 91.1 4.6 4.6e-09 36.6 0.2 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EKX33971.1 - 2.5e-23 81.4 7.9 5.1e-05 23.5 0.2 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EKX33971.1 - 6e-22 75.4 3.9 0.00013 22.1 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EKX33971.1 - 5.6e-18 64.8 9.6 3.1e-07 30.5 0.4 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) DUF5519 PF17648.1 EKX33971.1 - 0.043 13.7 0.5 0.18 11.7 0.2 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5519) FemAB_like PF04339.12 EKX33971.1 - 0.22 10.6 0.8 12 4.8 0.1 2.7 1 1 1 2 2 2 0 Peptidogalycan biosysnthesis/recognition SMC_N PF02463.19 EKX33973.1 - 3.5e-28 98.5 3.4 6.2e-16 58.5 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EKX33973.1 - 8.3e-23 81.9 4.5 8.3e-23 81.9 4.5 6.6 1 1 3 4 4 2 1 AAA domain AAA_15 PF13175.6 EKX33973.1 - 8.8e-09 35.5 16.9 8.8e-09 35.5 16.9 3.7 2 2 1 3 3 2 1 AAA ATPase domain AAA_29 PF13555.6 EKX33973.1 - 2.2e-05 24.1 0.0 4.6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 EKX33973.1 - 0.00098 18.8 0.0 0.00098 18.8 0.0 4.8 4 2 1 6 6 6 1 AAA domain AAA_21 PF13304.6 EKX33973.1 - 0.0013 18.6 0.1 0.0013 18.6 0.1 3.1 3 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 EKX33973.1 - 0.0067 16.9 1.0 0.0067 16.9 1.0 5.5 3 1 1 4 4 3 1 ABC transporter FmdE PF02663.14 EKX33973.1 - 0.011 15.8 0.0 0.011 15.8 0.0 4.9 3 2 1 4 4 3 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon SMC_hinge PF06470.13 EKX33973.1 - 0.012 15.9 0.0 0.053 13.8 0.0 2.2 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain AAA_25 PF13481.6 EKX33973.1 - 0.12 11.9 0.0 0.57 9.7 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EKX33973.1 - 0.15 12.5 1.1 0.46 10.9 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX33973.1 - 0.15 12.4 0.0 0.15 12.4 0.0 3.4 3 2 0 3 3 2 0 AAA ATPase domain Vac_Fusion PF02346.16 EKX33973.1 - 7.2 6.3 14.8 0.85 9.3 0.1 4.6 4 0 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 FYVE PF01363.21 EKX33974.1 - 1.6e-20 73.0 7.1 1.9e-20 72.8 7.1 1.1 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 EKX33974.1 - 0.0036 17.5 5.9 0.0039 17.4 5.9 1.1 1 0 0 1 1 1 1 FYVE-type zinc finger DZR PF12773.7 EKX33974.1 - 0.26 11.4 9.6 1.3 9.1 2.1 2.3 1 1 1 2 2 2 0 Double zinc ribbon Ank_5 PF13857.6 EKX33975.1 - 4.5e-22 77.8 0.6 1.5e-07 31.6 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX33975.1 - 5.2e-21 75.0 0.0 2.4e-12 47.2 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX33975.1 - 4.2e-20 69.7 0.2 6.3e-05 23.1 0.0 3.6 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EKX33975.1 - 4.5e-18 64.8 0.7 1.1e-05 25.7 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EKX33975.1 - 3.2e-17 62.7 0.0 1.7e-11 44.4 0.0 2.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) BNIP3 PF06553.12 EKX33975.1 - 0.24 11.0 0.0 0.4 10.3 0.0 1.3 1 1 0 1 1 1 0 BNIP3 Ank_2 PF12796.7 EKX33979.1 - 1e-23 83.7 0.4 2.9e-14 53.4 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX33979.1 - 1.8e-22 79.4 1.9 1e-07 32.4 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX33979.1 - 7.4e-15 53.6 0.4 0.0036 17.7 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 EKX33979.1 - 4.1e-13 49.1 0.0 4.3e-05 23.8 0.2 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EKX33979.1 - 5.7e-13 48.8 0.7 6.5e-08 32.7 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) PTCB-BRCT PF12738.7 EKX33979.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 twin BRCT domain RNase_T PF00929.24 EKX33980.1 - 8.3e-17 62.2 0.0 1.3e-16 61.6 0.0 1.3 1 1 0 1 1 1 1 Exonuclease Thymidylate_kin PF02223.17 EKX33981.1 - 6.2e-29 101.0 0.0 6.8e-29 100.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 EKX33981.1 - 0.0039 17.4 0.0 0.062 13.5 0.0 2.0 1 1 1 2 2 2 2 AAA domain PRK PF00485.18 EKX33981.1 - 0.12 12.0 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family CCDC24 PF15669.5 EKX33982.1 - 0.056 13.3 4.3 0.44 10.4 0.3 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 24 family Gon7 PF08738.10 EKX33983.1 - 0.098 12.7 5.2 0.22 11.6 5.2 1.6 1 0 0 1 1 1 0 Gon7 family EspB_PE PF18625.1 EKX33983.1 - 1.3 9.6 15.5 0.43 11.1 4.0 3.1 3 0 0 3 3 3 0 ESX-1 secreted protein B PE domain SPOUT_MTase PF02590.17 EKX33983.1 - 2.6 8.0 7.5 1.5 8.7 3.2 2.2 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase Acyl-CoA_dh_M PF02770.19 EKX33984.1 - 0.016 15.4 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain Nefa_Nip30_N PF10187.9 EKX33984.1 - 0.24 11.8 1.6 0.6 10.5 1.6 1.6 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 TPR_11 PF13414.6 EKX33985.1 - 0.002 17.8 0.2 0.0052 16.4 0.2 1.7 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.17 EKX33985.1 - 0.014 15.4 1.7 0.014 15.4 1.7 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EKX33985.1 - 0.02 14.9 1.5 0.1 12.7 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX33985.1 - 0.21 11.9 4.0 12 6.5 0.7 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat RRN3 PF05327.11 EKX33985.1 - 3.4 6.1 24.4 0.018 13.6 13.2 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 TPR_1 PF00515.28 EKX33985.1 - 5.6 7.0 9.1 0.19 11.6 1.7 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Nefa_Nip30_N PF10187.9 EKX33987.1 - 8.9e-06 26.0 5.7 2e-05 24.9 5.7 1.5 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 PA PF02225.22 EKX33988.1 - 1.9e-11 43.8 0.0 0.00031 20.7 0.0 2.5 2 0 0 2 2 2 2 PA domain MORN PF02493.20 EKX33988.1 - 6.1e-08 32.1 1.4 0.011 15.6 0.0 3.3 3 0 0 3 3 3 2 MORN repeat zf-UBP PF02148.19 EKX33992.1 - 0.00055 20.2 1.6 0.00073 19.8 1.6 1.3 1 1 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-C2HC5 PF06221.13 EKX33992.1 - 0.0024 17.8 3.5 0.0024 17.8 3.5 1.5 1 1 0 1 1 1 1 Putative zinc finger motif, C2HC5-type RWP-RK PF02042.15 EKX33993.1 - 2.4e-14 53.0 0.1 4.5e-14 52.1 0.1 1.5 1 0 0 1 1 1 1 RWP-RK domain HTH_6 PF01418.17 EKX33993.1 - 0.024 14.6 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family RWP-RK PF02042.15 EKX33995.1 - 3.3e-14 52.6 0.0 6.3e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain MFS_1 PF07690.16 EKX34000.1 - 4.2e-21 75.3 3.0 4.7e-21 75.1 3.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EKX34000.1 - 5.6e-06 25.5 8.9 6.5e-06 25.3 7.4 1.6 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 EKX34000.1 - 0.00057 19.3 0.4 0.00077 18.8 0.4 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 EKX34000.1 - 0.008 15.1 1.5 0.0097 14.8 1.5 1.3 1 0 0 1 1 1 1 MFS_1 like family DUF4149 PF13664.6 EKX34000.1 - 0.076 13.3 0.7 0.076 13.3 0.7 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4149) LRR_4 PF12799.7 EKX34001.1 - 1.1e-05 25.7 1.6 0.00021 21.6 0.3 2.7 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EKX34001.1 - 0.0027 17.6 5.8 1.4 9.2 0.0 3.7 3 0 0 3 3 3 2 Leucine Rich repeat LRR_8 PF13855.6 EKX34001.1 - 0.0077 16.0 1.6 0.036 13.8 0.4 2.5 2 0 0 2 2 2 1 Leucine rich repeat Shadoo PF14999.6 EKX34001.1 - 0.029 14.5 1.4 0.093 12.8 1.6 1.7 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective SDA1 PF05285.12 EKX34001.1 - 3.1 7.1 29.7 4.2 6.7 29.7 1.1 1 0 0 1 1 1 0 SDA1 RNA_pol_Rpc4 PF05132.14 EKX34002.1 - 1.9e-12 47.9 0.6 9.9e-09 35.8 0.0 3.1 3 0 0 3 3 3 2 RNA polymerase III RPC4 TPR_11 PF13414.6 EKX34003.1 - 2.8e-32 110.1 0.7 1.6e-07 30.9 0.0 6.1 2 2 4 6 6 6 5 TPR repeat TPR_1 PF00515.28 EKX34003.1 - 9.9e-31 104.3 0.0 1.7e-05 24.5 0.0 5.1 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 EKX34003.1 - 2.5e-27 92.7 0.0 4.9e-05 23.1 0.0 5.2 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 EKX34003.1 - 4.4e-22 76.9 1.2 0.0014 19.2 0.0 6.1 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.6 EKX34003.1 - 9.8e-22 75.3 0.0 2e-05 24.5 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 EKX34003.1 - 1.1e-21 76.9 4.0 1.8e-08 34.6 0.1 3.9 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX34003.1 - 1.2e-21 77.1 0.3 2.3e-10 41.0 0.0 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX34003.1 - 1.3e-21 75.3 0.0 3.5e-05 23.9 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 EKX34003.1 - 1.7e-17 62.1 0.2 0.0017 18.2 0.1 5.4 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 EKX34003.1 - 2.2e-15 56.1 0.0 0.003 18.1 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 EKX34003.1 - 6.2e-15 55.1 1.3 0.00025 21.1 0.1 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 EKX34003.1 - 8.2e-15 55.1 3.4 1.7e-06 28.4 0.0 4.2 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX34003.1 - 1.3e-13 50.3 8.4 0.021 14.7 0.1 5.5 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_4 PF07721.14 EKX34003.1 - 9.9e-13 47.4 1.5 0.24 12.1 0.4 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat BTAD PF03704.17 EKX34003.1 - 3.5e-07 30.8 1.8 0.0029 18.1 0.1 3.1 1 1 1 3 3 3 2 Bacterial transcriptional activator domain TPR_MalT PF17874.1 EKX34003.1 - 4.5e-07 29.6 4.6 0.0016 17.9 0.2 2.3 1 1 1 2 2 2 2 MalT-like TPR region TPR_15 PF13429.6 EKX34003.1 - 5.6e-07 29.1 2.3 0.045 13.0 0.0 3.7 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.6 EKX34003.1 - 4.2e-06 27.0 0.6 0.25 11.7 0.0 3.4 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.9 EKX34003.1 - 2.2e-05 24.3 1.4 0.096 12.4 0.0 2.3 1 1 0 2 2 2 2 Tetratricopeptide repeat-like domain TPR_3 PF07720.12 EKX34003.1 - 7.6e-05 22.6 1.5 3.6 7.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat MIT PF04212.18 EKX34003.1 - 0.00018 21.5 1.1 3.7 7.7 0.0 4.0 4 0 0 4 4 4 2 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 EKX34003.1 - 0.0014 18.8 0.1 0.45 10.8 0.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 YfiO PF13525.6 EKX34003.1 - 0.0016 18.2 0.1 0.0023 17.7 0.1 1.3 1 1 0 1 1 1 1 Outer membrane lipoprotein ANAPC5 PF12862.7 EKX34003.1 - 0.0021 18.1 0.9 3.7 7.7 0.0 3.8 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 5 Cohesin_load PF10345.9 EKX34003.1 - 0.0025 16.3 0.2 0.0068 14.9 0.1 1.7 1 1 0 2 2 2 1 Cohesin loading factor Nterm_IS4 PF13006.7 EKX34003.1 - 0.0034 17.6 0.0 0.021 15.0 0.0 2.1 2 1 0 2 2 2 1 Insertion element 4 transposase N-terminal DUF627 PF04781.12 EKX34003.1 - 0.0038 17.2 0.1 0.23 11.5 0.0 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF627) DUF4810 PF16068.5 EKX34003.1 - 0.01 16.3 0.4 26 5.5 0.0 3.9 1 1 4 5 5 5 0 Domain of unknown function (DUF4810) EST1_DNA_bind PF10373.9 EKX34003.1 - 0.03 13.8 0.2 0.19 11.2 0.1 2.0 2 0 0 2 2 2 0 Est1 DNA/RNA binding domain RPN7 PF10602.9 EKX34003.1 - 0.04 13.6 0.0 2.4 7.8 0.0 2.6 2 1 1 3 3 3 0 26S proteasome subunit RPN7 Aida_N PF08910.10 EKX34003.1 - 0.043 14.2 0.3 64 4.0 0.0 3.6 3 1 1 4 4 4 0 Aida N-terminus PknG_TPR PF16918.5 EKX34003.1 - 0.048 12.4 0.6 0.17 10.6 0.6 1.7 1 1 0 1 1 1 0 Protein kinase G tetratricopeptide repeat SNAP PF14938.6 EKX34003.1 - 0.062 12.7 0.9 1 8.7 0.3 2.6 1 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_5 PF12688.7 EKX34003.1 - 0.23 11.7 1.6 34 4.7 0.0 3.4 3 1 0 3 3 3 0 Tetratrico peptide repeat Q_salvage PF10343.9 EKX34007.1 - 3.4e-24 85.9 0.2 5.9e-24 85.1 0.2 1.3 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family PBP_GOBP PF01395.22 EKX34011.1 - 0.069 13.3 2.4 0.083 13.0 0.5 2.1 2 1 0 2 2 2 0 PBP/GOBP family SOBP PF15279.6 EKX34013.1 - 4.1 7.9 13.1 5.2 7.6 13.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SpoU_methylase PF00588.19 EKX34015.1 - 1.3e-26 93.5 0.0 1.4e-26 93.4 0.0 1.0 1 0 0 1 1 1 1 SpoU rRNA Methylase family PAS_9 PF13426.7 EKX34017.1 - 1.8e-06 28.1 0.0 0.049 13.9 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_8 PF13188.7 EKX34017.1 - 6e-05 23.0 0.0 0.028 14.5 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 EKX34017.1 - 0.001 19.0 0.0 0.014 15.3 0.0 2.4 2 1 0 2 2 2 1 PAS fold GTP-bdg_N PF13167.6 EKX34019.1 - 3.7e-30 104.4 0.1 1.2e-29 102.8 0.1 2.0 2 0 0 2 2 2 1 GTP-binding GTPase N-terminal GTP-bdg_M PF16360.5 EKX34019.1 - 1.9e-15 57.2 10.6 1.9e-15 57.2 10.6 2.3 2 1 0 2 2 2 1 GTP-binding GTPase Middle Region MMR_HSR1 PF01926.23 EKX34019.1 - 3.1e-11 43.4 0.1 1.5e-10 41.1 0.0 2.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EKX34019.1 - 0.00077 19.6 0.0 0.0043 17.1 0.0 2.1 2 0 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 EKX34019.1 - 0.0018 18.2 0.0 0.0098 15.8 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 EKX34019.1 - 0.0047 17.5 0.5 0.03 14.8 0.0 2.3 1 1 1 2 2 2 1 ABC transporter FeoB_N PF02421.18 EKX34019.1 - 0.0053 16.3 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_23 PF13476.6 EKX34019.1 - 0.014 16.0 2.7 1.3 9.5 0.2 2.5 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 EKX34019.1 - 0.034 13.6 0.0 0.13 11.7 0.0 2.0 1 1 1 2 2 2 0 ADP-ribosylation factor family AAA_14 PF13173.6 EKX34019.1 - 0.054 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain PAS_9 PF13426.7 EKX34020.1 - 2.1e-06 27.9 0.0 0.019 15.2 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS_8 PF13188.7 EKX34020.1 - 5.4e-05 23.1 0.0 0.0079 16.2 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 EKX34020.1 - 0.00028 20.9 0.0 0.0021 18.1 0.0 2.2 2 1 1 3 3 3 1 PAS fold Adaptin_binding PF10199.9 EKX34023.1 - 0.095 13.3 0.8 3.7 8.2 0.0 2.4 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 NYD-SP12_N PF15015.6 EKX34024.1 - 0.017 13.5 0.4 0.022 13.2 0.4 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal Pkinase_Tyr PF07714.17 EKX34025.1 - 1.5e-37 129.3 0.0 3.3e-37 128.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX34025.1 - 2.2e-35 122.3 0.0 5.5e-35 121.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EKX34025.1 - 0.0012 17.7 0.0 0.0012 17.7 0.0 2.4 2 1 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EKX34025.1 - 0.003 16.9 0.0 0.0064 15.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EKX34025.1 - 0.0038 16.6 0.0 0.0095 15.3 0.0 1.6 1 0 0 1 1 1 1 Kinase-like PDZ PF00595.24 EKX34025.1 - 0.06 13.7 0.1 0.18 12.2 0.1 1.8 1 0 0 1 1 1 0 PDZ domain APH PF01636.23 EKX34025.1 - 0.06 13.3 2.1 0.072 13.0 0.1 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF1515 PF07439.11 EKX34025.1 - 0.91 9.6 3.0 2.2 8.3 3.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) TFIIA PF03153.13 EKX34025.1 - 4.1 7.3 18.3 6.1 6.7 18.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sec34 PF04136.15 EKX34025.1 - 4.6 7.1 11.4 1 9.3 3.3 3.2 2 1 1 3 3 3 0 Sec34-like family Syntaxin-6_N PF09177.11 EKX34025.1 - 6.3 7.4 12.6 0.27 11.8 5.8 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal 2OG-FeII_Oxy_3 PF13640.6 EKX34027.1 - 2e-06 28.6 0.0 8.8e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 EKX34027.1 - 0.00073 20.2 0.0 0.0012 19.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PPL5 PF18168.1 EKX34028.1 - 0.044 13.1 13.0 0.059 12.7 13.0 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Peptidase_S46 PF10459.9 EKX34028.1 - 0.11 11.1 20.1 0.14 10.7 20.1 1.1 1 0 0 1 1 1 0 Peptidase S46 ICE2 PF08426.10 EKX34028.1 - 0.13 11.4 0.4 0.2 10.7 0.3 1.3 1 1 0 1 1 1 0 ICE2 Velvet PF11754.8 EKX34028.1 - 0.2 11.6 3.7 0.23 11.4 3.7 1.1 1 0 0 1 1 1 0 Velvet factor Dynactin_p62 PF05502.13 EKX34028.1 - 0.25 10.1 11.4 0.34 9.6 11.4 1.3 1 0 0 1 1 1 0 Dynactin p62 family Vfa1 PF08432.10 EKX34028.1 - 0.73 10.1 21.5 1.1 9.6 21.5 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 EKX34028.1 - 0.99 7.6 16.2 1.2 7.3 16.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 EKX34028.1 - 1.2 7.2 12.4 1.4 7.0 12.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein WDCP PF15390.6 EKX34028.1 - 1.3 7.4 10.8 1.5 7.1 10.8 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Borrelia_P83 PF05262.11 EKX34028.1 - 1.4 7.3 25.5 2.1 6.7 25.5 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Presenilin PF01080.17 EKX34028.1 - 1.5 7.5 11.5 1.7 7.3 11.5 1.1 1 0 0 1 1 1 0 Presenilin MDM10 PF12519.8 EKX34028.1 - 1.6 7.5 11.6 1.8 7.3 11.6 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Atg14 PF10186.9 EKX34028.1 - 1.9 7.5 15.8 2.5 7.1 15.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TP53IP5 PF15331.6 EKX34028.1 - 2.8 8.0 14.5 4.4 7.4 14.5 1.3 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 AAA_11 PF13086.6 EKX34028.1 - 4 7.2 13.9 6 6.6 13.9 1.4 1 0 0 1 1 1 0 AAA domain GBP_C PF02841.14 EKX34028.1 - 7.4 5.9 31.9 11 5.3 31.9 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Exonuc_VII_L PF02601.15 EKX34028.1 - 7.7 6.0 15.4 10 5.6 15.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit CLN3 PF02487.17 EKX34028.1 - 8.7 5.3 8.2 11 4.9 8.2 1.2 1 0 0 1 1 1 0 CLN3 protein Velvet PF11754.8 EKX34030.1 - 0.032 14.2 0.3 0.032 14.2 0.3 1.1 1 0 0 1 1 1 0 Velvet factor ICE2 PF08426.10 EKX34030.1 - 0.054 12.6 0.0 0.072 12.2 0.0 1.1 1 0 0 1 1 1 0 ICE2 DUF3402 PF11882.8 EKX34030.1 - 0.072 12.2 11.2 0.097 11.8 11.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) Dynactin_p62 PF05502.13 EKX34030.1 - 0.078 11.7 7.4 0.1 11.3 7.4 1.1 1 0 0 1 1 1 0 Dynactin p62 family Peptidase_S46 PF10459.9 EKX34030.1 - 0.13 10.9 14.1 0.18 10.4 14.1 1.1 1 0 0 1 1 1 0 Peptidase S46 PPL5 PF18168.1 EKX34030.1 - 0.16 11.2 8.5 0.21 10.9 8.5 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Borrelia_P83 PF05262.11 EKX34030.1 - 0.18 10.2 16.8 0.27 9.7 16.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Connexin PF00029.19 EKX34030.1 - 0.38 10.5 8.4 0.54 10.0 8.4 1.2 1 0 0 1 1 1 0 Connexin Vfa1 PF08432.10 EKX34030.1 - 1.5 9.2 15.2 2 8.7 15.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Ax_dynein_light PF10211.9 EKX34030.1 - 2.4 8.1 18.2 3.9 7.4 18.2 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain FapA PF03961.13 EKX34030.1 - 2.8 6.4 9.5 3.6 6.1 9.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3782 PF12644.7 EKX34030.1 - 2.9 8.1 9.5 43 4.3 9.5 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) EssA PF10661.9 EKX34030.1 - 4.5 7.1 18.2 8.4 6.2 15.3 2.2 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA Peptidase_S49_N PF08496.10 EKX34030.1 - 5.3 7.1 15.0 4.4 7.3 13.5 1.6 2 0 0 2 2 2 0 Peptidase family S49 N-terminal CLN3 PF02487.17 EKX34030.1 - 6.5 5.7 6.1 8.8 5.3 6.1 1.2 1 0 0 1 1 1 0 CLN3 protein FAM76 PF16046.5 EKX34030.1 - 8.3 5.7 17.4 12 5.1 17.4 1.2 1 0 0 1 1 1 0 FAM76 protein Myb_DNA-binding PF00249.31 EKX34031.1 - 7.2e-08 32.5 0.0 2.6e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 Myb-like DNA-binding domain Ephrin_rec_like PF07699.13 EKX34032.1 - 6.1e-16 57.9 45.3 6e-06 25.9 1.9 7.0 5 2 1 6 6 6 5 Putative ephrin-receptor like NCD3G PF07562.14 EKX34032.1 - 7.6e-05 22.6 37.5 0.22 11.5 3.4 6.6 5 2 2 7 7 7 6 Nine Cysteines Domain of family 3 GPCR UPF0239 PF06783.11 EKX34033.1 - 0.91 9.7 2.9 2.9 8.1 0.4 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0239) CDC45 PF02724.14 EKX34034.1 - 0.031 12.6 4.1 0.39 9.0 0.2 2.0 2 0 0 2 2 2 0 CDC45-like protein Pap_E4 PF02711.14 EKX34034.1 - 1.1 10.2 5.1 1.6 9.7 0.9 2.6 2 0 0 2 2 2 0 E4 protein DnaJ PF00226.31 EKX34035.1 - 1.7e-15 56.9 1.1 4.2e-15 55.6 0.0 2.4 3 0 0 3 3 3 1 DnaJ domain PLAC8 PF04749.17 EKX34037.1 - 6.7e-15 55.9 12.5 8.2e-15 55.6 12.5 1.1 1 0 0 1 1 1 1 PLAC8 family EF-hand_1 PF00036.32 EKX34038.1 - 0.057 13.0 0.0 7 6.4 0.0 2.7 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 EKX34038.1 - 0.12 12.8 0.1 0.25 11.8 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair ketoacyl-synt PF00109.26 EKX34039.1 - 1.5e-12 47.7 0.0 5.9e-09 35.9 0.2 2.3 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EKX34039.1 - 1.2e-11 44.7 0.2 2.2e-11 43.8 0.2 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Pkinase PF00069.25 EKX34040.1 - 2.3e-56 191.1 0.3 1.7e-45 155.5 0.0 3.1 1 1 1 2 2 2 2 Protein kinase domain EF-hand_7 PF13499.6 EKX34040.1 - 1.4e-25 89.5 6.4 1.1e-13 51.4 0.4 2.5 2 0 0 2 2 2 2 EF-hand domain pair Pkinase_Tyr PF07714.17 EKX34040.1 - 8.1e-24 84.3 0.0 3.5e-17 62.5 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase EF-hand_1 PF00036.32 EKX34040.1 - 9.8e-21 71.7 8.6 1.1e-06 27.7 0.8 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EKX34040.1 - 7.8e-20 69.1 1.1 0.00055 19.7 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EKX34040.1 - 1.3e-16 60.1 8.9 9.6e-09 35.0 0.4 3.5 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_4 PF12763.7 EKX34040.1 - 2.8e-08 33.6 0.5 0.0051 16.7 0.1 2.7 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EKX34040.1 - 3.7e-08 33.6 0.6 0.0016 18.7 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 EKX34040.1 - 8.3e-06 25.1 3.0 0.014 14.9 0.2 3.8 4 0 0 4 4 4 1 EF hand SurA_N_3 PF13624.6 EKX34040.1 - 0.0012 18.7 0.4 0.0046 16.8 0.1 1.9 2 0 0 2 2 2 1 SurA N-terminal domain SurA_N_2 PF13623.6 EKX34040.1 - 0.035 14.0 0.1 0.91 9.4 0.0 2.2 2 0 0 2 2 2 0 SurA N-terminal domain DUF5580 PF17743.1 EKX34040.1 - 0.12 10.9 0.3 7.1 5.0 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5580) Creb_binding PF09030.10 EKX34040.1 - 0.15 12.8 1.0 0.23 12.2 0.3 1.6 2 0 0 2 2 1 0 Creb binding EF-hand_14 PF17959.1 EKX34040.1 - 0.16 12.3 0.8 28 5.2 0.1 2.7 3 0 0 3 3 2 0 EF-hand domain Spore_YtrH PF14034.6 EKX34040.1 - 0.17 12.1 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 Sporulation protein YtrH DUF2362 PF10154.9 EKX34042.1 - 1.6e-16 60.4 3.1 1.8e-11 43.7 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2362) DUF1759 PF03564.15 EKX34042.1 - 0.13 12.2 1.2 0.28 11.1 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) DUF2591 PF10765.9 EKX34043.1 - 0.062 13.6 0.0 0.09 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2591) MGAT2 PF05060.14 EKX34044.1 - 7.4e-14 51.6 0.1 3.4e-07 29.7 0.2 2.2 1 1 1 2 2 2 2 N-acetylglucosaminyltransferase II (MGAT2) DUF4214 PF13946.6 EKX34044.1 - 3.7e-10 39.7 0.1 0.00057 19.9 0.0 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF4214) DUF4667 PF15700.5 EKX34044.1 - 0.00062 19.9 1.0 0.00062 19.9 1.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4667) IQCJ-SCHIP1 PF15157.6 EKX34044.1 - 0.15 11.9 5.6 0.35 10.7 5.6 1.6 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif SR-25 PF10500.9 EKX34044.1 - 0.28 10.8 26.7 0.012 15.2 19.2 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Toxin_2 PF00451.19 EKX34044.1 - 2.2 8.7 5.8 14 6.1 2.3 2.8 2 0 0 2 2 2 0 Scorpion short toxin, BmKK2 RAP1 PF07218.11 EKX34044.1 - 9.9 4.3 6.3 15 3.7 6.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) WSD PF15613.6 EKX34048.1 - 1.4e-05 25.5 0.4 1.4e-05 25.5 0.4 4.4 3 2 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WHIM1 PF15612.6 EKX34048.1 - 0.0062 16.1 1.3 0.022 14.3 0.3 2.2 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 V_ATPase_I PF01496.19 EKX34048.1 - 5.3 4.8 10.4 6 4.7 7.7 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family SepSecS PF05889.13 EKX34049.1 - 7.7e-126 419.9 0.1 9.1e-126 419.7 0.1 1.0 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 EKX34049.1 - 2.2e-08 33.8 0.1 3.1e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EKX34049.1 - 5.8e-06 25.7 0.0 9.1e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Peptidase_S9 PF00326.21 EKX34050.1 - 1.2e-39 135.9 0.0 1.8e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EKX34050.1 - 7.7e-11 42.1 0.5 1.2e-07 31.6 0.3 3.2 2 1 1 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EKX34050.1 - 2.2e-09 37.0 0.1 7.4e-05 22.1 0.1 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 EKX34050.1 - 3.8e-07 29.9 0.0 3.3e-06 26.8 0.0 2.2 1 1 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.12 EKX34050.1 - 1.5e-06 27.1 0.0 2.3e-05 23.2 0.0 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 EKX34050.1 - 2.1e-06 27.8 0.1 4.5e-06 26.7 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 EKX34050.1 - 0.00053 19.7 0.2 0.0019 17.9 0.1 1.9 2 1 0 2 2 2 1 Putative esterase DUF2920 PF11144.8 EKX34050.1 - 0.0028 16.9 0.0 0.0046 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) PD40 PF07676.12 EKX34050.1 - 0.0059 16.5 0.1 2.1 8.4 0.0 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat BAAT_C PF08840.11 EKX34050.1 - 0.015 15.2 0.0 0.14 12.1 0.0 2.1 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S28 PF05577.12 EKX34050.1 - 0.047 12.5 0.0 0.091 11.5 0.0 1.4 1 0 0 1 1 1 0 Serine carboxypeptidase S28 PhoPQ_related PF10142.9 EKX34050.1 - 0.2 10.3 0.0 0.27 9.8 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Abhydrolase_6 PF12697.7 EKX34050.1 - 0.43 11.1 11.9 0.076 13.6 4.5 3.0 2 2 0 2 2 2 0 Alpha/beta hydrolase family NUDIX PF00293.28 EKX34051.1 - 7.4e-19 68.1 0.0 1.2e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Exo_endo_phos PF03372.23 EKX34052.1 - 2.1e-09 37.3 0.0 2.9e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AbiEi_4 PF13338.6 EKX34052.1 - 0.045 13.9 0.8 0.24 11.6 0.1 2.4 3 0 0 3 3 3 0 Transcriptional regulator, AbiEi antitoxin LRR_8 PF13855.6 EKX34054.1 - 1.8e-49 165.3 52.2 1.9e-12 46.8 0.9 4.9 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 EKX34054.1 - 2.8e-13 49.8 34.6 8.6e-07 29.2 5.1 5.4 3 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX34054.1 - 1.9e-11 44.0 0.0 8.2e-07 29.0 0.0 2.3 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EKX34054.1 - 6e-06 26.1 23.9 0.042 14.4 0.3 7.5 7 1 0 7 7 7 2 Leucine Rich Repeat LRR_9 PF14580.6 EKX34054.1 - 4.9e-05 22.9 3.3 0.019 14.5 0.6 2.4 1 1 1 2 2 2 2 Leucine-rich repeat GIT_SHD PF08518.11 EKX34054.1 - 0.0028 17.3 0.2 14 5.4 0.0 4.8 5 0 0 5 5 5 1 Spa2 homology domain (SHD) of GIT DUF3188 PF11384.8 EKX34054.1 - 0.017 14.8 0.2 96 2.8 0.0 5.4 6 1 1 7 7 7 0 Protein of unknown function (DUF3188) HGTP_anticodon PF03129.20 EKX34055.1 - 3.5e-23 81.6 0.0 7.9e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EKX34055.1 - 3.6e-10 40.1 0.0 3.8e-09 36.7 0.0 2.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EKX34056.1 - 3.5e-23 81.6 0.0 7.7e-23 80.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EKX34056.1 - 4.6e-10 39.8 0.0 3.7e-09 36.8 0.0 2.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) zf-TRAF PF02176.18 EKX34056.1 - 1.4 9.6 3.2 3.2 8.5 0.1 2.9 3 0 0 3 3 3 0 TRAF-type zinc finger HGTP_anticodon PF03129.20 EKX34057.1 - 2.2e-23 82.2 0.0 6.3e-23 80.8 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EKX34057.1 - 2.4e-10 40.7 0.0 2.5e-09 37.4 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) zf-TRAF PF02176.18 EKX34057.1 - 1.1 9.9 3.3 2.7 8.8 0.1 2.9 3 0 0 3 3 3 0 TRAF-type zinc finger DUF1979 PF09322.10 EKX34058.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1979) DUF4816 PF16086.5 EKX34058.1 - 0.9 9.5 6.0 2.5 8.1 6.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4816) Hemagglutinin PF00509.18 EKX34059.1 - 0.0074 14.8 1.9 0.0084 14.6 1.9 1.0 1 0 0 1 1 1 1 Haemagglutinin BLOC1_2 PF10046.9 EKX34059.1 - 0.022 15.0 1.9 0.022 15.0 1.9 1.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fmp27_WPPW PF10359.9 EKX34059.1 - 0.023 13.5 3.7 0.025 13.5 3.7 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DHR10 PF18595.1 EKX34059.1 - 0.024 14.7 7.6 0.03 14.4 6.6 1.7 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain CEP209_CC5 PF16574.5 EKX34059.1 - 0.024 14.8 2.1 0.024 14.8 2.1 1.5 1 1 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 BORCS7 PF16088.5 EKX34059.1 - 0.032 14.5 2.0 0.15 12.3 0.8 2.0 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 7 Laminin_II PF06009.12 EKX34059.1 - 0.039 14.0 2.3 0.043 13.8 2.3 1.3 1 1 0 1 1 1 0 Laminin Domain II KLRAQ PF10205.9 EKX34059.1 - 0.042 14.1 2.7 0.047 13.9 1.7 1.6 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein Tropomyosin_1 PF12718.7 EKX34059.1 - 0.043 14.0 6.1 0.062 13.4 6.1 1.4 1 1 0 1 1 1 0 Tropomyosin like RIG-I_C PF18119.1 EKX34059.1 - 0.061 13.3 3.0 0.09 12.8 2.2 1.7 1 1 1 2 2 2 0 RIG-I receptor C-terminal domain DUF724 PF05266.14 EKX34059.1 - 0.083 12.7 4.0 0.089 12.6 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) WXG100 PF06013.12 EKX34059.1 - 0.093 13.0 1.7 1.3 9.3 0.1 2.5 3 0 0 3 3 3 0 Proteins of 100 residues with WXG DUF1664 PF07889.12 EKX34059.1 - 0.18 11.8 2.2 0.51 10.4 1.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 EKX34059.1 - 0.2 10.9 3.0 0.21 10.8 3.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein XhlA PF10779.9 EKX34059.1 - 4.2 7.6 7.6 13 6.1 0.9 2.8 1 1 2 3 3 3 0 Haemolysin XhlA PsbQ PF05757.11 EKX34060.1 - 9.3e-06 25.5 2.3 0.0014 18.5 0.1 2.2 2 0 0 2 2 2 2 Oxygen evolving enhancer protein 3 (PsbQ) DUF4148 PF13663.6 EKX34060.1 - 1.4 9.2 7.4 10 6.4 1.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) CX9C PF16860.5 EKX34061.1 - 0.01 15.9 8.6 0.043 13.8 2.0 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NDUF_B7 PF05676.13 EKX34061.1 - 0.014 15.1 7.8 0.47 10.2 0.3 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) PP2C_2 PF13672.6 EKX34061.1 - 0.015 15.0 0.1 0.016 14.9 0.1 1.1 1 0 0 1 1 1 0 Protein phosphatase 2C Cmc1 PF08583.10 EKX34061.1 - 0.024 14.7 11.8 0.45 10.6 4.0 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 EKX34061.1 - 0.05 13.7 9.3 2.5 8.3 1.6 3.2 2 2 1 3 3 3 0 CHCH domain GCK PF07802.11 EKX34061.1 - 0.4 11.1 10.7 0.22 12.0 4.7 2.4 1 1 1 2 2 2 0 GCK domain Pet191_N PF10203.9 EKX34061.1 - 0.49 10.7 10.2 0.78 10.1 4.5 2.5 1 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 SKA1 PF07160.12 EKX34062.1 - 2 8.2 3.9 3.2 7.5 3.9 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Methyltransf_21 PF05050.12 EKX34063.1 - 2.4e-09 37.4 0.0 3.4e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain TraV PF09676.10 EKX34065.1 - 0.0003 21.8 1.0 0.39 11.7 0.0 2.1 2 0 0 2 2 2 2 Type IV conjugative transfer system lipoprotein (TraV) Tenui_PVC2 PF06656.11 EKX34065.1 - 0.26 9.2 0.0 11 3.7 0.0 2.0 2 0 0 2 2 2 0 Tenuivirus PVC2 protein CAF-1_p150 PF11600.8 EKX34065.1 - 0.91 9.2 6.0 6.3 6.5 0.9 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TUDOR_5 PF18359.1 EKX34066.1 - 0.013 15.2 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 Tudor-knot PF11717.8 EKX34066.1 - 0.24 11.3 0.9 0.62 10.0 0.9 1.8 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain zf-C2H2_4 PF13894.6 EKX34066.1 - 8.2 7.6 6.1 0.81 10.7 0.8 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger Ank_5 PF13857.6 EKX34067.1 - 7e-14 51.7 0.0 4.5e-07 30.0 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX34067.1 - 3.4e-10 40.3 0.0 1.2e-09 38.5 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX34067.1 - 3e-08 34.1 0.0 4.5e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX34067.1 - 1.4e-06 28.1 0.0 0.0053 17.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EKX34067.1 - 9.1e-06 25.9 0.0 0.0012 19.2 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat TMEM65 PF10507.9 EKX34068.1 - 3.9e-38 129.8 3.8 4.4e-38 129.6 3.8 1.0 1 0 0 1 1 1 1 Transmembrane protein 65 MtrG PF04210.13 EKX34068.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G PAP_fibrillin PF04755.12 EKX34070.1 - 6.5e-15 55.6 0.2 1.6e-13 51.1 0.2 2.0 1 1 0 1 1 1 1 PAP_fibrillin HEAT PF02985.22 EKX34071.1 - 1.5e-39 130.6 27.6 0.0037 17.4 0.0 13.5 14 0 0 14 14 14 12 HEAT repeat HEAT_2 PF13646.6 EKX34071.1 - 2.4e-34 117.6 4.9 1.3e-06 28.7 0.0 8.2 3 3 4 8 8 8 7 HEAT repeats Vac14_Fab1_bd PF12755.7 EKX34071.1 - 3.2e-14 53.3 4.7 0.012 16.2 0.1 7.1 3 3 3 7 7 7 5 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EKX34071.1 - 6e-12 45.8 12.5 0.00074 20.0 0.2 8.0 8 2 2 10 10 10 4 HEAT-like repeat Adaptin_N PF01602.20 EKX34071.1 - 2e-10 39.9 8.5 1.5e-05 23.8 0.0 3.6 2 1 1 3 3 3 3 Adaptin N terminal region CLASP_N PF12348.8 EKX34071.1 - 6.5e-07 29.1 5.4 0.42 10.1 0.1 5.0 1 1 4 5 5 5 3 CLASP N terminal Arm PF00514.23 EKX34071.1 - 8e-07 28.9 0.1 0.18 11.9 0.0 6.0 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EKX34071.1 - 7.9e-06 26.0 9.7 0.00095 19.2 0.8 4.9 1 1 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 AMP-binding PF00501.28 EKX34072.1 - 2.4e-86 290.0 0.0 3.8e-86 289.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ATG22 PF11700.8 EKX34073.1 - 7.9e-106 354.5 19.3 1.1e-105 354.0 19.3 1.2 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DUF4407 PF14362.6 EKX34073.1 - 0.64 9.3 2.3 1.2 8.4 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1924 PF09086.11 EKX34078.1 - 0.065 13.6 0.3 0.23 11.8 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1924) DUF179 PF02622.15 EKX34079.1 - 2.1e-23 83.0 0.7 2.3e-18 66.7 0.2 3.4 3 1 0 3 3 3 2 Uncharacterized ACR, COG1678 DUF1198 PF06711.11 EKX34079.1 - 0.0025 17.9 0.1 0.0046 17.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1198) Metal_resist PF13801.6 EKX34079.1 - 0.071 13.3 0.2 0.21 11.7 0.2 1.7 1 0 0 1 1 1 0 Heavy-metal resistance Death PF00531.22 EKX34079.1 - 0.13 12.5 0.5 0.45 10.7 0.1 2.1 2 0 0 2 2 2 0 Death domain Abhydrolase_6 PF12697.7 EKX34080.1 - 0.00094 19.8 0.0 0.0012 19.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 EKX34080.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.8 EKX34080.1 - 0.014 14.7 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 EKX34080.1 - 0.021 14.9 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain UPF0227 PF05728.12 EKX34080.1 - 0.1 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.7 EKX34080.1 - 0.2 11.4 0.0 0.36 10.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3141 PF11339.8 EKX34080.1 - 0.23 9.8 0.1 0.32 9.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) DUF2798 PF11391.8 EKX34081.1 - 0.12 12.4 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) ALMT PF11744.8 EKX34081.1 - 1.4 7.7 3.5 1.9 7.2 3.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter WWE PF02825.20 EKX34082.1 - 4.1e-07 30.5 0.4 6.1e-07 29.9 0.4 1.4 1 1 0 1 1 1 1 WWE domain DnaJ PF00226.31 EKX34083.1 - 4.8e-24 84.3 0.4 5.3e-24 84.1 0.4 1.0 1 0 0 1 1 1 1 DnaJ domain Mei5_like PF17021.5 EKX34083.1 - 0.065 13.3 0.0 0.075 13.1 0.0 1.1 1 0 0 1 1 1 0 Putative double-strand recombination repair-like Transcrip_act PF04949.13 EKX34083.1 - 0.097 12.5 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Transcriptional activator PH PF00169.29 EKX34084.1 - 0.00018 21.9 0.1 0.00091 19.7 0.0 2.3 2 0 0 2 2 2 1 PH domain PKD_channel PF08016.12 EKX34085.1 - 4.5e-62 210.1 3.5 4.5e-62 210.1 3.5 1.8 1 1 1 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 EKX34085.1 - 4.7e-07 29.3 18.0 4.7e-07 29.3 18.0 1.7 2 0 0 2 2 2 1 Ion transport protein Phasin PF05597.11 EKX34085.1 - 0.0062 16.5 1.6 0.0062 16.5 1.6 1.5 2 0 0 2 2 2 1 Poly(hydroxyalcanoate) granule associated protein (phasin) LRR_8 PF13855.6 EKX34086.1 - 2.6e-12 46.3 14.0 4.6e-05 23.1 1.1 3.6 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EKX34086.1 - 3.2e-08 33.7 15.9 0.042 14.3 1.0 3.7 2 2 0 3 3 3 3 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 EKX34086.1 - 5.9e-07 29.7 5.7 1.5e-05 25.2 5.2 2.5 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 EKX34086.1 - 1.5e-05 24.8 9.8 9.4 7.2 0.0 6.3 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.6 EKX34086.1 - 0.00012 21.8 10.6 1 9.6 0.1 5.3 5 0 0 5 5 5 3 Leucine Rich repeat HrcA_DNA-bdg PF03444.15 EKX34088.1 - 0.067 12.8 0.3 0.21 11.3 0.3 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding DUF5320 PF17253.2 EKX34088.1 - 0.79 10.8 6.4 0.31 12.1 1.5 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5320) Fib_alpha PF08702.10 EKX34088.1 - 0.85 9.8 7.1 1.1 9.5 5.5 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family MCLC PF05934.11 EKX34088.1 - 4.4 5.9 5.9 6 5.5 5.9 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Cpn60_TCP1 PF00118.24 EKX34089.1 - 4.9e-155 516.9 7.8 5.7e-155 516.7 7.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ParA PF10609.9 EKX34090.1 - 3.3e-66 223.3 0.1 4.6e-66 222.8 0.1 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase FeS_assembly_P PF01883.19 EKX34090.1 - 2.1e-07 31.0 0.0 5.9e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein Rieske PF00355.26 EKX34091.1 - 2.5e-13 49.8 0.2 3.6e-13 49.3 0.2 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain CytB6-F_Fe-S PF08802.10 EKX34091.1 - 5.9e-07 29.4 0.7 5.9e-07 29.4 0.7 2.4 2 0 0 2 2 2 1 Cytochrome B6-F complex Fe-S subunit WHAMM-JMY_N PF15920.5 EKX34091.1 - 0.039 13.8 0.6 0.067 13.1 0.6 1.4 1 0 0 1 1 1 0 N-terminal of Junction-mediating and WASP homolog-associated SHP PF03579.13 EKX34093.1 - 0.25 11.4 0.1 0.25 11.4 0.1 2.1 2 0 0 2 2 2 0 Small hydrophobic protein TMEM43 PF07787.12 EKX34093.1 - 5.8 6.2 9.0 0.42 10.0 3.2 1.9 1 1 0 2 2 2 0 Transmembrane protein 43 DUF3953 PF13129.6 EKX34094.1 - 0.037 13.8 0.2 1.9 8.3 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) DHC_N1 PF08385.12 EKX34095.1 - 2.7e-186 620.5 15.7 2.7e-186 620.5 15.7 3.4 3 1 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 EKX34095.1 - 2.4e-142 473.7 0.1 2.1e-141 470.7 0.0 2.7 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EKX34095.1 - 4.7e-124 414.5 8.2 4.7e-124 414.5 8.2 4.2 4 1 1 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EKX34095.1 - 4.6e-95 317.9 0.2 1.4e-94 316.3 0.2 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EKX34095.1 - 1.1e-86 290.8 0.4 3.2e-82 276.2 0.0 4.5 4 0 0 4 4 4 2 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EKX34095.1 - 3.5e-78 261.7 0.0 1e-77 260.2 0.0 1.9 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 EKX34095.1 - 4.6e-62 208.8 0.1 6e-57 192.1 0.0 4.5 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EKX34095.1 - 4.5e-54 182.7 0.1 2e-53 180.6 0.1 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 EKX34095.1 - 5.1e-50 170.4 17.3 1.4e-49 169.0 17.3 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EKX34095.1 - 1.2e-38 131.9 0.0 1.4e-37 128.4 0.0 3.1 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EKX34095.1 - 2.5e-23 82.6 0.3 1.6e-22 79.9 0.3 2.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EKX34095.1 - 4e-18 65.5 0.1 4.8e-17 62.0 0.0 3.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 EKX34095.1 - 6.3e-18 65.1 0.0 7.1e-08 32.5 0.0 5.2 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA PF00004.29 EKX34095.1 - 1.2e-07 32.3 0.2 1.3 9.4 0.0 5.2 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EKX34095.1 - 2.8e-06 27.6 0.1 7 6.9 0.0 5.5 5 0 0 5 5 5 1 AAA domain AAA_18 PF13238.6 EKX34095.1 - 0.00076 20.0 0.3 5.2 7.6 0.0 4.2 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 EKX34095.1 - 0.047 13.1 0.3 2 7.7 0.1 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI MA3 PF02847.17 EKX34095.1 - 0.068 13.2 4.5 0.18 11.8 0.1 4.1 4 0 0 4 4 3 0 MA3 domain RAM PF15320.6 EKX34095.1 - 0.14 12.8 0.0 0.56 10.8 0.0 2.0 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein AAA_16 PF13191.6 EKX34095.1 - 0.24 11.8 3.9 32 4.8 0.0 4.9 5 0 0 5 5 4 0 AAA ATPase domain Sel1 PF08238.12 EKX34096.1 - 3.2e-74 243.7 37.2 3.7e-12 46.5 0.8 7.2 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.6 EKX34096.1 - 7.8e-09 35.6 20.9 2.9 8.7 0.1 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 EKX34096.1 - 4.5e-05 24.0 20.1 1.4 9.6 1.1 6.7 2 2 5 7 7 7 5 Tetratricopeptide repeat Nup96 PF12110.8 EKX34096.1 - 7.2e-05 22.1 4.0 0.00084 18.5 0.2 3.2 1 1 1 3 3 3 1 Nuclear protein 96 ANAPC3 PF12895.7 EKX34096.1 - 0.00022 21.4 18.0 0.011 15.9 1.8 4.5 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 RWP-RK PF02042.15 EKX34097.1 - 1.8e-13 50.2 0.0 2.7e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 RWP-RK domain PDZ_2 PF13180.6 EKX34100.1 - 0.075 13.4 0.0 0.24 11.8 0.0 1.9 2 0 0 2 2 2 0 PDZ domain Glyco_transf_41 PF13844.6 EKX34101.1 - 1.1e-44 152.7 0.2 2e-23 82.6 0.0 3.0 2 1 1 3 3 3 3 Glycosyl transferase family 41 FKBP_C PF00254.28 EKX34102.1 - 9.6e-36 122.0 0.0 4.4e-35 119.9 0.0 1.8 1 1 1 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF1589 PF07628.11 EKX34102.1 - 0.04 14.1 0.0 0.05 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1589) Zn_clus PF00172.18 EKX34103.1 - 1.2e-05 25.3 8.7 3.3e-05 23.9 8.7 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 EKX34104.1 - 1.2e-05 25.3 8.7 3.1e-05 24.0 8.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 EKX34105.1 - 1.1e-05 25.5 8.7 3.3e-05 23.9 8.7 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RAP PF08373.10 EKX34106.1 - 3.5e-10 39.8 0.0 0.0013 18.8 0.1 2.5 2 0 0 2 2 2 2 RAP domain DUF4373 PF14297.6 EKX34106.1 - 0.026 15.3 0.1 9.4 7.1 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4373) HTH_51 PF18558.1 EKX34106.1 - 0.11 12.4 1.6 78 3.2 0.0 5.0 6 0 0 6 6 6 0 Helix-turn-helix domain zf-AD PF07776.15 EKX34106.1 - 0.13 12.5 0.8 6.2 7.1 0.0 3.6 3 0 0 3 3 3 0 Zinc-finger associated domain (zf-AD) Keratin_2_head PF16208.5 EKX34106.1 - 0.15 12.2 16.2 0.41 10.8 16.2 1.7 1 0 0 1 1 1 0 Keratin type II head DUF5320 PF17253.2 EKX34106.1 - 0.85 10.7 16.6 2.2 9.4 16.6 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5320) RWP-RK PF02042.15 EKX34107.1 - 1.4e-14 53.8 0.2 2.1e-14 53.2 0.2 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX34107.1 - 0.061 13.1 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Motile_Sperm PF00635.26 EKX34108.1 - 1e-06 28.6 0.2 1.6e-06 27.9 0.2 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF3879 PF12995.7 EKX34108.1 - 0.093 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3879) zf-CCCH PF00642.24 EKX34109.1 - 3.8e-05 23.5 0.6 3.8e-05 23.5 0.6 3.9 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EKX34109.1 - 0.013 15.5 0.3 0.013 15.5 0.3 4.3 4 0 0 4 4 4 0 Zinc finger domain zf-CCCH_4 PF18044.1 EKX34109.1 - 0.84 9.5 15.4 0.92 9.4 0.7 4.2 4 0 0 4 4 4 0 CCCH-type zinc finger TSNAXIP1_N PF15739.5 EKX34110.1 - 0.082 13.3 0.6 0.29 11.5 0.0 2.0 2 1 0 2 2 2 0 Translin-associated factor X-interacting N-terminus HSF_DNA-bind PF00447.17 EKX34111.1 - 4.3e-27 94.6 0.4 5.9e-27 94.1 0.4 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding Beta_helix_2 PF18835.1 EKX34111.1 - 0.2 11.4 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Beta helix repeat of Inulin fructotransferase Presenilin PF01080.17 EKX34112.1 - 0.00028 19.8 16.4 0.00028 19.8 16.4 2.6 2 1 0 2 2 1 1 Presenilin DDHD PF02862.17 EKX34112.1 - 0.00029 21.1 8.5 0.00029 21.1 8.5 3.1 2 1 0 2 2 2 1 DDHD domain AAA_11 PF13086.6 EKX34112.1 - 0.0047 16.8 13.8 0.0047 16.8 13.8 2.3 2 0 0 2 2 2 1 AAA domain TERB2 PF15101.6 EKX34112.1 - 0.017 15.2 23.3 0.086 12.9 23.3 2.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PPL5 PF18168.1 EKX34112.1 - 0.06 12.6 16.1 0.16 11.2 16.1 1.7 1 0 0 1 1 1 0 Prim-pol family 5 RNA_pol_Rpc4 PF05132.14 EKX34112.1 - 0.086 13.3 20.1 0.098 13.1 12.5 3.3 3 0 0 3 3 3 0 RNA polymerase III RPC4 DUF5308 PF17233.2 EKX34112.1 - 0.087 13.0 13.3 0.028 14.6 9.7 2.0 2 0 0 2 2 1 0 Family of unknown function (DUF5308) RP-C_C PF11800.8 EKX34112.1 - 0.13 12.4 14.5 0.41 10.7 14.5 1.8 1 0 0 1 1 1 0 Replication protein C C-terminal region HemX PF04375.14 EKX34112.1 - 0.22 10.8 43.5 0.53 9.5 43.5 1.5 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF1645 PF07816.11 EKX34112.1 - 0.23 12.0 16.1 0.7 10.4 8.6 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1645) FAM76 PF16046.5 EKX34112.1 - 0.24 10.7 31.7 0.38 10.1 17.7 2.8 2 0 0 2 2 2 0 FAM76 protein CPSF100_C PF13299.6 EKX34112.1 - 0.41 10.8 17.2 1.3 9.2 15.2 2.6 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Velvet PF11754.8 EKX34112.1 - 0.83 9.5 23.4 0.2 11.6 17.8 2.3 2 0 0 2 2 2 0 Velvet factor RR_TM4-6 PF06459.12 EKX34112.1 - 1 9.1 28.0 0.06 13.2 20.3 2.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DAG_kinase_N PF14513.6 EKX34112.1 - 1.2 9.3 26.9 0.34 11.1 19.4 3.1 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus Pex14_N PF04695.13 EKX34112.1 - 1.8 9.2 38.1 4.9 7.8 38.1 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Plasmodium_Vir PF05795.11 EKX34112.1 - 1.8 7.9 11.8 0.77 9.1 6.7 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein BORG_CEP PF14957.6 EKX34112.1 - 2.1 9.5 22.1 1.9 9.7 15.0 3.2 2 0 0 2 2 2 0 Cdc42 effector eIF-3_zeta PF05091.12 EKX34112.1 - 2.5 7.0 33.8 0.29 10.1 28.2 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Peptidase_S15 PF02129.18 EKX34112.1 - 2.7 7.5 15.2 5 6.6 15.2 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) TFIIA PF03153.13 EKX34112.1 - 4.4 7.2 59.4 0.045 13.7 50.2 2.2 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Tim54 PF11711.8 EKX34112.1 - 4.5 6.0 21.8 0.26 10.0 16.1 1.7 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Exonuc_VII_L PF02601.15 EKX34112.1 - 5.6 6.4 24.5 16 5.0 24.5 1.7 1 0 0 1 1 1 0 Exonuclease VII, large subunit FAM60A PF15396.6 EKX34112.1 - 5.7 6.9 24.7 0.94 9.4 17.4 3.0 3 0 0 3 3 3 0 Protein Family FAM60A UPF0560 PF10577.9 EKX34112.1 - 6.2 5.2 35.7 15 4.0 35.7 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Hydin_ADK PF17213.3 EKX34112.1 - 6.4 7.0 17.7 0.97 9.7 12.3 2.5 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Phage_GPO PF05929.11 EKX34112.1 - 6.6 6.3 22.9 17 4.9 22.9 1.7 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase FAM176 PF14851.6 EKX34112.1 - 9.9 5.8 18.4 4.8 6.8 12.1 3.1 3 0 0 3 3 3 0 FAM176 family DUF1090 PF06476.12 EKX34115.1 - 0.012 15.7 79.9 0.39 10.8 3.1 8.9 3 2 6 9 9 9 0 Protein of unknown function (DUF1090) Prok_Ub PF14454.6 EKX34115.1 - 0.072 12.8 0.2 14 5.4 0.0 3.5 3 0 0 3 3 3 0 Prokaryotic Ubiquitin Cupin_8 PF13621.6 EKX34116.1 - 0.17 11.6 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Cupin-like domain HMGL-like PF00682.19 EKX34118.1 - 9.8e-94 313.8 1.5 1.5e-93 313.1 1.5 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 EKX34118.1 - 2.4e-32 111.6 0.5 4.7e-32 110.7 0.5 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain DUF1652 PF07865.11 EKX34118.1 - 0.12 12.3 0.7 0.93 9.4 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1652) Pyridoxal_deC PF00282.19 EKX34119.1 - 2e-88 296.6 0.0 3e-88 296.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 EKX34119.1 - 4.6e-14 52.4 0.0 5.9e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EKX34119.1 - 9.4e-09 34.7 0.0 1.4e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V SepSecS PF05889.13 EKX34119.1 - 0.056 12.1 0.0 0.092 11.4 0.0 1.3 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Flavi_capsid PF01003.19 EKX34119.1 - 0.11 12.3 0.0 0.36 10.6 0.0 1.8 2 0 0 2 2 2 0 Flavivirus capsid protein C ABC_membrane PF00664.23 EKX34120.1 - 1.1e-47 163.0 10.4 1.6e-47 162.5 10.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EKX34120.1 - 6.3e-23 81.8 0.0 2.3e-21 76.8 0.0 2.4 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EKX34120.1 - 1.5e-05 24.6 0.3 0.019 14.4 0.1 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EKX34120.1 - 0.00017 21.9 0.0 0.00075 19.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EKX34120.1 - 0.001 18.8 0.1 0.012 15.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EKX34120.1 - 0.0011 18.7 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EKX34120.1 - 0.0017 18.8 1.5 0.0068 16.8 0.4 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 EKX34120.1 - 0.0039 17.7 0.0 0.011 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain 60KD_IMP PF02096.20 EKX34120.1 - 0.0085 16.0 0.3 0.084 12.8 0.3 2.2 1 1 0 1 1 1 1 60Kd inner membrane protein AAA PF00004.29 EKX34120.1 - 0.011 16.2 0.1 0.055 13.9 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EKX34120.1 - 0.016 15.1 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 EKX34120.1 - 0.047 13.4 0.4 7.8 6.2 0.3 2.5 2 1 0 2 2 2 0 IstB-like ATP binding protein AAA_21 PF13304.6 EKX34120.1 - 0.067 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Amino_oxidase PF01593.24 EKX34121.1 - 3e-18 66.4 0.0 1.3e-17 64.3 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EKX34121.1 - 7.7e-16 58.1 0.1 2.2e-15 56.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EKX34121.1 - 3.4e-11 42.9 0.7 4.8e-09 35.8 0.4 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EKX34121.1 - 1.5e-09 37.9 2.0 2.9e-06 27.1 1.2 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 EKX34121.1 - 9e-09 34.9 0.1 7.1e-07 28.7 0.0 2.4 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 EKX34121.1 - 1.9e-08 33.4 0.1 4.2e-05 22.4 0.3 2.3 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 EKX34121.1 - 2.8e-08 33.3 0.1 8.6e-05 21.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EKX34121.1 - 1.3e-06 28.0 0.4 3.1e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EKX34121.1 - 1.9e-06 27.4 0.8 6.2e-06 25.7 0.5 1.9 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 EKX34121.1 - 5.9e-06 25.6 1.6 0.0026 16.9 0.2 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A GMC_oxred_N PF00732.19 EKX34121.1 - 8.9e-06 25.3 0.4 5.4e-05 22.7 0.1 2.1 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox PF00070.27 EKX34121.1 - 0.00032 21.2 0.8 0.0018 18.8 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 EKX34121.1 - 0.00049 18.7 0.1 0.019 13.5 0.0 2.2 2 0 0 2 2 2 1 GDP dissociation inhibitor Lycopene_cycl PF05834.12 EKX34121.1 - 0.00086 18.5 0.5 0.22 10.5 0.1 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EKX34121.1 - 0.0038 16.5 0.2 0.073 12.3 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 EKX34121.1 - 0.019 15.0 0.2 4.3 7.3 0.1 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MCRA PF06100.11 EKX34121.1 - 0.04 12.7 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 MCRA family DUF2247 PF10004.9 EKX34121.1 - 0.071 12.9 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) NAD_binding_9 PF13454.6 EKX34121.1 - 0.071 13.1 0.7 14 5.6 0.1 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 EKX34121.1 - 1.4 8.8 4.2 0.73 9.7 0.4 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3450 PF11932.8 EKX34122.1 - 0.0077 15.6 0.5 0.011 15.1 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) ZapB PF06005.12 EKX34122.1 - 0.0093 16.4 0.5 0.023 15.1 0.5 1.6 1 0 0 1 1 1 1 Cell division protein ZapB RCC1 PF00415.18 EKX34123.1 - 2.9e-44 149.5 10.4 1.8e-13 50.8 0.2 5.6 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX34123.1 - 1.7e-36 123.3 10.0 3.5e-10 39.4 3.4 4.2 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat Peptidase_C25_C PF03785.14 EKX34123.1 - 0.013 15.3 0.1 7.6 6.4 0.0 3.2 2 1 1 3 3 3 0 Peptidase family C25, C terminal ig-like domain DUF3446 PF11928.8 EKX34123.1 - 0.11 12.8 13.5 0.17 12.2 13.5 1.3 1 0 0 1 1 1 0 Early growth response N-terminal domain SR-25 PF10500.9 EKX34123.1 - 0.7 9.5 20.3 0.93 9.1 20.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF508 PF04370.12 EKX34123.1 - 1.9 8.2 8.0 3 7.6 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF508) MHYT PF03707.16 EKX34124.1 - 0.038 14.1 0.5 5 7.4 0.0 2.9 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat DUF4131 PF13567.6 EKX34124.1 - 5.1 6.7 19.9 0.097 12.3 2.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Zn_clus PF00172.18 EKX34125.1 - 2.1e-08 34.2 9.4 3.9e-08 33.3 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mfa1 PF17445.2 EKX34126.1 - 0.033 14.2 0.3 0.15 12.1 0.3 2.1 1 0 0 1 1 1 0 Mating factor A1 Uso1_p115_head PF04869.14 EKX34128.1 - 1e-07 31.4 0.0 2.5e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region HEAT_2 PF13646.6 EKX34128.1 - 0.0012 19.2 1.0 0.0052 17.2 0.1 2.5 2 2 0 2 2 2 1 HEAT repeats Mo25 PF08569.11 EKX34128.1 - 0.0013 18.1 0.1 0.0025 17.2 0.0 1.4 2 0 0 2 2 2 1 Mo25-like Adaptin_N PF01602.20 EKX34128.1 - 0.017 13.7 0.3 0.5 8.9 0.2 2.3 1 1 1 2 2 2 0 Adaptin N terminal region HEAT PF02985.22 EKX34128.1 - 0.25 11.7 2.2 11 6.6 0.1 3.4 3 0 0 3 3 3 0 HEAT repeat TPR_12 PF13424.6 EKX34129.1 - 3e-14 53.1 0.0 1e-08 35.3 0.0 2.9 2 1 1 3 3 3 3 Tetratricopeptide repeat SHNi-TPR PF10516.9 EKX34129.1 - 1.2e-10 40.7 0.5 7.1e-10 38.2 0.3 2.2 2 0 0 2 2 2 1 SHNi-TPR TPR_1 PF00515.28 EKX34129.1 - 1.3e-06 27.9 0.9 0.12 12.3 0.7 3.3 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX34129.1 - 5.9e-06 26.1 0.1 0.15 12.3 0.1 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX34129.1 - 9.5e-05 22.2 0.2 1.1 9.5 0.0 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX34129.1 - 0.00018 21.2 0.0 2.5 8.1 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat SPO22 PF08631.10 EKX34129.1 - 0.00044 19.8 1.3 0.00071 19.1 0.4 1.7 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_6 PF13174.6 EKX34129.1 - 0.045 14.4 0.1 3.9 8.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PAS PF00989.25 EKX34130.1 - 3e-199 649.0 12.2 3.1e-26 91.6 0.1 8.3 8 0 0 8 8 8 8 PAS fold PAS_4 PF08448.10 EKX34130.1 - 9e-115 376.8 3.7 8.7e-15 54.9 0.1 8.3 8 0 0 8 8 8 8 PAS fold PAS_9 PF13426.7 EKX34130.1 - 4.5e-105 345.0 22.5 1.7e-13 50.7 0.1 8.4 8 0 0 8 8 8 8 PAS domain PAS_3 PF08447.12 EKX34130.1 - 2e-63 210.7 0.1 2.3e-07 31.0 0.0 8.5 8 0 0 8 8 8 8 PAS fold PAS_8 PF13188.7 EKX34130.1 - 1.1e-49 165.7 13.3 3.1e-05 23.9 0.1 8.5 8 0 0 8 8 8 8 PAS domain HATPase_c PF02518.26 EKX34130.1 - 6.6e-29 100.7 0.4 3.2e-28 98.5 0.1 2.4 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EKX34130.1 - 5.8e-27 94.1 0.1 1.5e-26 92.8 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EKX34130.1 - 1.2e-17 63.7 0.1 4.5e-17 61.8 0.1 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF5588 PF17826.1 EKX34130.1 - 3.4e-08 32.8 0.9 2.2 7.1 0.0 6.2 6 0 0 6 6 6 1 Family of unknown function (DUF5588) DUF1824 PF08854.10 EKX34130.1 - 3.7e-06 26.9 3.8 30 4.6 0.0 7.1 7 0 0 7 7 7 0 Domain of unknown function (DUF1824) Y_phosphatase2 PF03162.13 EKX34130.1 - 1.1e-05 25.1 0.0 16 5.0 0.0 6.8 8 0 0 8 8 8 0 Tyrosine phosphatase family sCache_3_3 PF17202.4 EKX34130.1 - 0.00016 22.0 14.3 13 6.3 0.0 7.9 8 0 0 8 8 8 0 Single cache domain 3 GARS_C PF02843.16 EKX34130.1 - 0.0056 16.9 6.9 44 4.5 0.0 6.3 7 0 0 7 7 7 0 Phosphoribosylglycinamide synthetase, C domain ProQ PF04352.13 EKX34130.1 - 0.012 15.5 5.6 18 5.3 0.1 6.1 6 0 0 6 6 6 0 ProQ/FINO family Cache_3-Cache_2 PF17201.4 EKX34130.1 - 0.096 11.9 17.1 15 4.7 0.0 7.4 9 0 0 9 9 9 0 Cache 3/Cache 2 fusion domain TMEM210 PF15195.6 EKX34130.1 - 0.11 13.0 0.6 41 4.6 0.0 3.9 4 0 0 4 4 3 0 TMEM210 family DUF3052 PF11253.8 EKX34130.1 - 0.88 9.5 5.1 1.1e+02 2.7 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF3052) DUF1433 PF07252.11 EKX34130.1 - 3 8.2 9.7 20 5.5 0.0 6.6 6 5 5 11 11 11 0 Protein of unknown function (DUF1433) SAS4 PF15460.6 EKX34130.1 - 6.6 6.9 9.7 1.2e+02 2.9 0.0 5.5 6 0 0 6 6 6 0 Something about silencing, SAS, complex subunit 4 Sel1 PF08238.12 EKX34131.1 - 1.1e-22 80.0 15.0 3.1e-06 27.7 0.0 9.1 9 0 0 9 9 9 4 Sel1 repeat FAM176 PF14851.6 EKX34131.1 - 0.025 14.2 0.1 0.025 14.2 0.1 2.3 1 1 1 2 2 2 0 FAM176 family Presenilin PF01080.17 EKX34131.1 - 0.12 11.1 6.9 0.17 10.6 6.9 1.2 1 0 0 1 1 1 0 Presenilin Anophelin PF10731.9 EKX34131.1 - 0.27 11.1 2.2 0.55 10.1 2.2 1.5 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito SR-25 PF10500.9 EKX34131.1 - 0.46 10.1 32.1 1.2 8.7 32.1 1.7 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF515 PF04415.12 EKX34131.1 - 1.3 7.3 7.9 1.9 6.8 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SOBP PF15279.6 EKX34131.1 - 1.4 9.5 4.8 1.8 9.1 4.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Apt1 PF10351.9 EKX34131.1 - 2 7.2 11.1 2.7 6.8 11.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain AF-4 PF05110.13 EKX34131.1 - 3.1 5.8 20.6 5.3 5.0 20.6 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein zf-C2H2 PF00096.26 EKX34132.1 - 0.0028 18.0 13.1 1.5 9.4 1.5 3.5 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 EKX34132.1 - 0.0038 17.9 1.1 0.0038 17.9 1.1 1.6 2 0 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 EKX34132.1 - 0.0072 17.1 11.8 0.26 12.2 1.1 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 EKX34132.1 - 0.066 13.4 7.1 0.22 11.7 0.2 2.6 1 1 0 2 2 2 0 Aberrant zinc-finger TerC PF03741.16 EKX34133.1 - 3.2e-52 176.8 2.2 4e-52 176.5 2.2 1.1 1 0 0 1 1 1 1 Integral membrane protein TerC family DUF475 PF04332.15 EKX34133.1 - 0.0027 17.5 2.5 0.0027 17.5 2.5 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF475) EF-hand_6 PF13405.6 EKX34133.1 - 0.0067 16.3 0.4 0.025 14.5 0.2 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 EKX34133.1 - 0.087 12.4 0.3 0.21 11.2 0.3 1.6 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 EKX34133.1 - 0.088 12.4 0.2 0.28 10.8 0.2 1.8 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 EKX34133.1 - 0.16 12.5 0.2 0.36 11.3 0.2 1.5 1 0 0 1 1 1 0 EF-hand domain pair DsbD_2 PF13386.6 EKX34133.1 - 0.22 11.5 8.3 0.33 10.9 3.4 2.2 1 1 1 2 2 2 0 Cytochrome C biogenesis protein transmembrane region BofA PF07441.11 EKX34133.1 - 3.3 8.0 7.5 0.65 10.2 0.5 2.9 2 1 1 3 3 3 0 SigmaK-factor processing regulatory protein BofA PPR_2 PF13041.6 EKX34134.1 - 4.7e-09 36.3 0.0 0.025 14.8 0.0 5.8 5 1 1 6 6 6 2 PPR repeat family PPR_3 PF13812.6 EKX34134.1 - 3.8e-07 30.1 0.0 0.12 12.4 0.0 5.1 5 0 0 5 5 5 2 Pentatricopeptide repeat domain T2SSF PF00482.23 EKX34134.1 - 0.068 13.1 0.3 21 5.1 0.0 3.9 5 0 0 5 5 5 0 Type II secretion system (T2SS), protein F GMP_synt_C PF00958.22 EKX34134.1 - 0.096 12.8 0.1 6.6 6.9 0.0 2.6 2 0 0 2 2 2 0 GMP synthase C terminal domain DivIC PF04977.15 EKX34136.1 - 0.12 12.2 18.2 0.15 11.8 4.4 3.5 4 1 0 4 4 4 0 Septum formation initiator bZIP_1 PF00170.21 EKX34136.1 - 0.66 10.1 14.8 0.031 14.4 6.6 2.9 1 1 1 2 2 2 0 bZIP transcription factor HP0268 PF18618.1 EKX34136.1 - 0.67 10.4 7.1 1.1 9.8 1.2 2.8 1 1 1 2 2 2 0 HP0268 FlaC_arch PF05377.11 EKX34136.1 - 0.67 10.4 12.1 0.52 10.7 1.2 3.4 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF948 PF06103.11 EKX34136.1 - 0.98 9.7 3.8 1.4 9.2 0.8 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 EKX34136.1 - 1.3 9.2 19.5 0.22 11.7 14.7 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Phlebovirus_NSM PF07246.11 EKX34136.1 - 3.4 7.0 14.7 7.8 5.8 14.7 1.6 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Prominin PF05478.11 EKX34136.1 - 6.4 4.6 7.4 3.7 5.4 4.1 1.4 1 1 0 1 1 1 0 Prominin Atg14 PF10186.9 EKX34136.1 - 6.8 5.7 18.6 0.89 8.6 14.4 1.6 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 PRKG1_interact PF15898.5 EKX34136.1 - 7.4 7.5 21.7 0.29 12.1 12.2 3.1 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain ABC_tran_CTD PF16326.5 EKX34136.1 - 8.7 6.7 10.6 1.8 8.9 3.1 2.9 1 1 1 2 2 2 0 ABC transporter C-terminal domain UPF0242 PF06785.11 EKX34137.1 - 0.021 15.0 13.7 0.036 14.2 13.7 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 EKX34137.1 - 0.21 11.1 5.6 0.28 10.7 5.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-K PF11802.8 EKX34137.1 - 0.23 11.0 15.4 0.35 10.4 15.4 1.3 1 0 0 1 1 1 0 Centromere-associated protein K DUF3552 PF12072.8 EKX34137.1 - 0.9 8.9 22.0 1.8 7.9 22.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF4407 PF14362.6 EKX34137.1 - 6.9 5.9 13.2 1.7 8.0 8.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) MULE PF10551.9 EKX34138.1 - 2.4e-06 27.8 0.0 3.2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 EKX34138.1 - 0.018 14.8 0.0 0.019 14.7 0.0 1.1 1 0 0 1 1 1 0 Transposase Transposase_mut PF00872.18 EKX34138.1 - 0.051 12.4 0.0 0.051 12.4 0.0 1.0 1 0 0 1 1 1 0 Transposase, Mutator family DUF3552 PF12072.8 EKX34139.1 - 0.11 11.9 15.0 0.2 11.1 15.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) FOXP-CC PF16159.5 EKX34139.1 - 0.14 12.8 2.7 0.16 12.7 0.0 2.3 2 0 0 2 2 2 0 FOXP coiled-coil domain YlqD PF11068.8 EKX34139.1 - 0.37 11.2 13.1 0.65 10.4 13.1 1.3 1 0 0 1 1 1 0 YlqD protein Sec2p PF06428.11 EKX34139.1 - 0.83 9.7 15.7 5.6 7.0 7.0 3.1 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p FAM76 PF16046.5 EKX34139.1 - 6.8 6.0 16.5 1.2e+02 1.8 15.8 2.3 1 1 0 1 1 1 0 FAM76 protein OmpH PF03938.14 EKX34139.1 - 7.3 6.9 18.5 1.4 9.2 15.2 1.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TMEM126 PF07114.11 EKX34141.1 - 0.055 12.9 0.0 0.057 12.8 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 126 Glyco_transf_8 PF01501.20 EKX34145.1 - 1.4e-11 44.4 0.0 4.3e-11 42.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 Lactamase_B PF00753.27 EKX34146.1 - 1.1e-18 68.0 0.6 1.2e-17 64.5 0.6 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EKX34146.1 - 0.0021 17.6 0.1 0.0048 16.4 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Thioredoxin_8 PF13905.6 EKX34147.1 - 6.2e-30 103.4 0.1 6.8e-18 64.8 0.0 3.7 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EKX34147.1 - 5.8e-12 46.0 0.0 0.00018 21.9 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.21 EKX34147.1 - 1.1e-06 28.6 0.1 0.058 13.3 0.0 3.4 2 2 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 EKX34147.1 - 2.9e-05 23.8 0.0 0.18 11.5 0.0 2.8 2 2 0 2 2 2 2 Redoxin Thioredoxin PF00085.20 EKX34147.1 - 5.2e-05 23.2 0.1 0.41 10.7 0.0 4.0 3 1 0 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.6 EKX34147.1 - 0.0033 17.4 0.0 0.011 15.7 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like domain HyaE PF07449.11 EKX34147.1 - 0.04 13.9 0.0 5.2 7.1 0.0 2.6 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE TrbC_Ftype PF09673.10 EKX34147.1 - 0.16 12.0 0.1 18 5.4 0.0 2.7 2 1 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein MORN PF02493.20 EKX34148.1 - 3.7e-23 80.0 61.6 8.5e-06 25.4 0.7 13.1 13 1 0 13 13 13 10 MORN repeat Lactamase_B PF00753.27 EKX34149.1 - 2.9e-19 69.9 0.8 3.2e-18 66.5 0.8 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EKX34149.1 - 0.002 17.6 0.1 0.0047 16.5 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain SpoIIE PF07228.12 EKX34150.1 - 3.5e-10 40.1 0.0 6.3e-10 39.3 0.0 1.4 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 EKX34150.1 - 5.7e-05 22.8 0.0 0.00018 21.2 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 EKX34150.1 - 0.0005 19.8 0.0 0.45 10.1 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C CDH1_2_SANT_HL1 PF18375.1 EKX34151.1 - 0.0012 19.5 1.4 0.0021 18.7 1.4 1.3 1 0 0 1 1 1 1 CDH1/2 SANT-Helical linker 1 DUF3450 PF11932.8 EKX34151.1 - 0.013 14.8 3.4 0.019 14.3 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) HemX PF04375.14 EKX34151.1 - 0.028 13.7 2.8 0.035 13.4 2.8 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase GAT PF03127.14 EKX34151.1 - 0.11 12.8 0.5 0.21 11.9 0.5 1.5 1 0 0 1 1 1 0 GAT domain DUF3573 PF12097.8 EKX34151.1 - 0.12 11.2 0.3 0.15 10.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF2673 PF10880.8 EKX34151.1 - 0.15 12.2 0.2 0.43 10.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) Tetraspanin PF00335.20 EKX34151.1 - 0.18 11.5 0.0 0.26 11.0 0.0 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF2968 PF11180.8 EKX34151.1 - 0.45 10.1 8.6 0.84 9.2 8.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) TMPIT PF07851.13 EKX34151.1 - 4 6.6 5.3 6 6.0 5.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein CCDC-167 PF15188.6 EKX34151.1 - 8.1 6.9 8.9 0.71 10.2 3.6 1.9 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 PhyH PF05721.13 EKX34153.1 - 4.5e-09 36.9 0.4 7.2e-08 32.9 0.4 2.2 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Ccdc124 PF06244.12 EKX34153.1 - 0.021 15.4 0.1 0.021 15.4 0.1 1.9 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 124 /Oxs1 SUR7 PF06687.12 EKX34153.1 - 0.034 13.8 0.4 0.052 13.2 0.4 1.2 1 0 0 1 1 1 0 SUR7/PalI family DUF5480 PF17576.2 EKX34153.1 - 0.069 13.1 1.4 0.14 12.2 0.8 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5480) 2OG-FeII_Oxy_5 PF13759.6 EKX34153.1 - 0.15 12.5 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Cupin_2 PF07883.11 EKX34153.1 - 0.15 11.8 0.0 1.7 8.4 0.0 2.4 3 0 0 3 3 3 0 Cupin domain Peptidase_S49_N PF08496.10 EKX34153.1 - 0.17 11.9 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FoP_duplication PF13865.6 EKX34154.1 - 0.05 14.1 5.4 0.17 12.5 0.2 2.4 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 HECT PF00632.25 EKX34155.1 - 1.4e-71 241.6 0.0 4.1e-71 240.0 0.0 1.8 2 1 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 EKX34155.1 - 0.0052 16.8 1.0 30 4.9 0.0 4.7 3 1 1 4 4 4 2 Armadillo/beta-catenin-like repeat Sgf11 PF08209.11 EKX34156.1 - 0.0009 18.8 4.3 0.43 10.2 0.3 2.6 2 0 0 2 2 2 2 Sgf11 (transcriptional regulation protein) Peptidase_M14 PF00246.24 EKX34158.1 - 2.2e-13 50.7 0.0 1.1e-12 48.4 0.0 2.0 2 1 0 2 2 2 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 EKX34158.1 - 3.9e-06 27.2 0.0 8.2e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 EKX34158.1 - 0.0033 16.5 0.0 0.0062 15.6 0.0 1.5 1 1 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family TPT PF03151.16 EKX34160.1 - 1.7e-86 290.2 8.4 2e-86 290.0 8.4 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EKX34160.1 - 2.5e-16 60.1 17.7 5.3e-10 39.6 2.6 2.5 2 2 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EKX34160.1 - 0.15 11.2 5.9 3.2 6.9 4.9 2.0 1 1 1 2 2 2 0 UAA transporter family SHMT PF00464.19 EKX34161.1 - 4.3e-176 585.4 0.0 5.1e-176 585.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 EKX34161.1 - 4.2e-07 29.5 0.0 6e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EKX34161.1 - 9.3e-06 25.2 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EKX34161.1 - 0.13 11.2 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V TPT PF03151.16 EKX34162.1 - 0.043 13.1 11.5 0.24 10.7 11.5 1.9 1 1 0 1 1 1 0 Triose-phosphate Transporter family EamA PF00892.20 EKX34162.1 - 0.28 11.4 22.8 0.02 15.0 12.3 2.3 2 0 0 2 2 2 0 EamA-like transporter family DUF676 PF05057.14 EKX34164.1 - 0.0011 18.5 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3657 PF12394.8 EKX34164.1 - 0.0086 16.6 0.1 0.019 15.5 0.1 1.6 1 0 0 1 1 1 1 Protein FAM135 Pkinase PF00069.25 EKX34165.1 - 5.2e-23 81.7 0.3 5.8e-23 81.6 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX34165.1 - 2.3e-15 56.6 0.7 2.6e-15 56.4 0.7 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX34165.1 - 6.8e-06 26.2 0.0 0.044 13.7 0.0 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EKX34165.1 - 0.0059 16.0 0.2 0.0066 15.8 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CATSPERG PF15064.6 EKX34165.1 - 0.031 12.1 0.1 0.052 11.4 0.1 1.3 1 1 0 1 1 1 0 Cation channel sperm-associated protein subunit gamma Pkinase_fungal PF17667.1 EKX34165.1 - 0.11 11.2 0.1 0.13 11.0 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase T2SSG PF08334.11 EKX34166.1 - 0.072 13.2 0.2 0.099 12.7 0.2 1.4 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein G C2 PF00168.30 EKX34168.1 - 6.1e-05 23.2 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain IQ PF00612.27 EKX34168.1 - 0.035 13.9 1.5 0.13 12.2 1.5 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif Pkinase PF00069.25 EKX34170.1 - 9.7e-53 179.2 0.0 1.4e-52 178.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX34170.1 - 7e-33 114.0 0.0 1e-32 113.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX34170.1 - 1.9e-05 23.6 0.0 4.5e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EKX34170.1 - 0.0016 17.8 0.0 0.0049 16.2 0.0 1.7 1 1 0 1 1 1 1 Kinase-like DNA_ligase_OB PF03120.16 EKX34170.1 - 0.0065 16.3 0.4 0.015 15.2 0.4 1.6 1 0 0 1 1 1 1 NAD-dependent DNA ligase OB-fold domain APH PF01636.23 EKX34170.1 - 0.084 12.8 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EKX34170.1 - 0.2 10.5 0.0 15 4.4 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EKX34170.1 - 0.22 10.6 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 HEAT_2 PF13646.6 EKX34171.1 - 7.9e-14 51.8 13.1 2.4e-07 31.1 1.1 4.6 5 1 0 5 5 5 2 HEAT repeats HEAT PF02985.22 EKX34171.1 - 1.7e-11 43.4 18.1 0.036 14.3 0.1 6.8 7 0 0 7 7 7 4 HEAT repeat HEAT_EZ PF13513.6 EKX34171.1 - 3.2e-06 27.5 3.2 0.18 12.3 0.3 4.8 3 1 1 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 EKX34171.1 - 7.2e-05 22.9 4.8 0.0043 17.1 0.9 3.3 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 EKX34171.1 - 0.00086 19.5 0.2 1 9.5 0.0 2.9 2 0 0 2 2 2 2 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 EKX34171.1 - 0.0025 17.8 0.1 1.4 9.1 0.0 4.1 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 EKX34171.1 - 0.0042 15.7 0.3 0.026 13.1 0.0 2.1 2 0 0 2 2 2 1 Adaptin N terminal region CLASP_N PF12348.8 EKX34171.1 - 0.064 12.8 0.2 6.3 6.3 0.0 2.5 2 0 0 2 2 2 0 CLASP N terminal Vac14_Fab1_bd PF12755.7 EKX34171.1 - 0.2 12.2 0.7 12 6.6 0.1 3.1 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region RasGEF_N_2 PF14663.6 EKX34171.1 - 1.7 9.1 3.3 5.3 7.5 0.1 3.2 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain PPR_3 PF13812.6 EKX34172.1 - 8.6e-37 125.0 4.7 1.2e-06 28.5 0.1 8.5 8 1 1 9 9 9 7 Pentatricopeptide repeat domain PPR_2 PF13041.6 EKX34172.1 - 7.9e-33 112.4 13.3 2.2e-07 31.0 0.2 11.0 9 2 2 11 11 11 7 PPR repeat family PPR_long PF17177.4 EKX34172.1 - 6.9e-21 74.6 0.9 3.8e-09 36.2 0.0 4.4 2 1 2 4 4 4 4 Pentacotripeptide-repeat region of PRORP ECSIT PF06239.11 EKX34172.1 - 2.3e-07 30.2 0.4 0.024 13.7 0.0 4.5 3 1 1 4 4 4 2 Evolutionarily conserved signalling intermediate in Toll pathway PPR PF01535.20 EKX34172.1 - 0.0036 17.5 28.2 15 6.1 0.0 11.3 13 0 0 13 13 13 1 PPR repeat PPR_1 PF12854.7 EKX34172.1 - 0.0093 15.6 17.8 2.4 7.9 0.0 8.0 9 1 0 9 9 9 2 PPR repeat ThiS-like PF14453.6 EKX34172.1 - 0.015 15.3 0.0 0.038 14.0 0.0 1.7 1 0 0 1 1 1 0 ThiS-like ubiquitin DUF4003 PF13170.6 EKX34172.1 - 0.022 14.1 0.0 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) RPM2 PF08579.11 EKX34172.1 - 0.19 12.1 0.2 3.3 8.1 0.1 2.8 3 0 0 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) Exog_C PF18026.1 EKX34172.1 - 7.7 6.7 5.8 70 3.6 0.0 3.9 5 0 0 5 5 5 0 Endo/exonuclease (EXOG) C-terminal domain CLTH PF10607.9 EKX34173.1 - 1.6e-22 80.0 0.0 2.4e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_5 PF14634.6 EKX34173.1 - 0.00012 22.0 1.9 0.00026 20.9 1.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EKX34173.1 - 0.00019 21.2 1.2 0.00036 20.3 1.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX34173.1 - 0.00031 20.7 2.0 0.0009 19.2 2.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EKX34173.1 - 0.0008 19.2 1.9 0.0018 18.1 1.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX34173.1 - 0.0013 18.6 1.6 0.0029 17.4 1.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EKX34173.1 - 0.0046 17.3 2.6 0.011 16.1 2.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX34173.1 - 0.029 14.2 3.6 0.06 13.2 3.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EKX34173.1 - 0.064 13.4 2.0 0.16 12.2 2.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C2HC5 PF06221.13 EKX34173.1 - 0.62 10.1 3.6 0.34 10.9 0.9 1.9 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type PPR_2 PF13041.6 EKX34174.1 - 6.6e-27 93.5 5.5 0.00035 20.7 0.1 8.6 7 1 1 8 8 8 7 PPR repeat family PPR_3 PF13812.6 EKX34174.1 - 8.6e-19 67.4 5.8 0.0001 22.3 0.0 8.2 5 3 4 9 9 9 4 Pentatricopeptide repeat domain PPR_long PF17177.4 EKX34174.1 - 4.6e-15 55.6 4.6 0.00032 20.1 0.2 5.3 4 2 0 4 4 4 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EKX34174.1 - 4.4e-05 23.1 2.2 36 4.2 0.3 7.1 9 0 0 9 9 9 0 PPR repeat Wzy_C PF04932.15 EKX34174.1 - 0.044 13.4 0.2 0.078 12.6 0.2 1.5 1 0 0 1 1 1 0 O-Antigen ligase LMF1 PF06762.14 EKX34174.1 - 0.13 11.3 4.5 0.19 10.8 4.5 1.2 1 0 0 1 1 1 0 Lipase maturation factor DUF3072 PF11272.8 EKX34174.1 - 0.14 12.1 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) Keratin_2_head PF16208.5 EKX34174.1 - 1.1 9.4 14.5 2.4 8.3 14.5 1.5 1 0 0 1 1 1 0 Keratin type II head DUF2663 PF10864.8 EKX34174.1 - 1.3 9.5 7.7 3.8 7.9 5.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) CBP_BcsG PF11658.8 EKX34174.1 - 2.3 6.5 6.6 14 4.0 6.9 2.1 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsG DUF2207 PF09972.9 EKX34174.1 - 3.3 6.4 7.4 5.5 5.6 7.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4191 PF13829.6 EKX34174.1 - 4 6.7 17.4 7.6 5.8 17.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) PPR PF01535.20 EKX34174.1 - 4.9 7.6 19.9 11 6.5 0.3 7.5 8 0 0 8 8 7 0 PPR repeat TPT PF03151.16 EKX34175.1 - 2e-69 234.2 10.2 1.9e-68 231.0 10.2 2.0 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EKX34175.1 - 0.00014 22.0 15.2 0.013 15.6 1.2 3.9 3 1 0 3 3 3 2 EamA-like transporter family Thioredoxin_8 PF13905.6 EKX34177.1 - 1.4e-23 83.0 0.0 1.8e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EKX34177.1 - 4.8e-05 23.3 0.0 5.9e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 EKX34177.1 - 9.5e-05 22.3 0.0 0.0046 16.9 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Redoxin PF08534.10 EKX34177.1 - 0.0049 16.6 0.0 0.0062 16.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.6 EKX34177.1 - 0.21 11.4 0.0 3.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin Glyco_trans_1_4 PF13692.6 EKX34178.1 - 3e-09 37.4 0.0 1e-07 32.4 0.0 2.8 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EKX34178.1 - 6.3e-06 26.7 0.1 1.2e-05 25.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.20 EKX34178.1 - 0.00072 19.1 0.0 0.019 14.5 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EKX34178.1 - 0.0064 16.5 0.1 0.027 14.5 0.1 2.0 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Macin PF14865.6 EKX34178.1 - 0.067 13.7 0.0 0.2 12.2 0.0 1.7 1 0 0 1 1 1 0 Macin Glyco_trans_1_2 PF13524.6 EKX34178.1 - 0.15 12.5 0.0 0.65 10.4 0.0 2.0 2 1 0 2 2 2 0 Glycosyl transferases group 1 DUF3682 PF12446.8 EKX34179.1 - 1.9 8.9 6.6 4.6 7.7 6.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) ARA70 PF12489.8 EKX34180.1 - 0.0064 16.7 0.4 0.013 15.6 0.4 1.5 1 0 0 1 1 1 1 Nuclear coactivator Lectin_N PF03954.14 EKX34180.1 - 0.057 13.2 1.4 2 8.2 0.2 2.4 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain FAM76 PF16046.5 EKX34180.1 - 2.3 7.5 6.3 3.2 7.0 6.3 1.2 1 0 0 1 1 1 0 FAM76 protein Exonuc_VII_L PF02601.15 EKX34180.1 - 2.5 7.6 11.0 5 6.6 10.9 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.14 EKX34180.1 - 4.9 7.5 10.2 3.4 8.0 0.8 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Peptidase_C13 PF01650.18 EKX34185.1 - 0.12 11.8 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Peptidase C13 family PQ-loop PF04193.14 EKX34188.1 - 6.5e-18 64.3 11.8 9.6e-10 38.1 1.8 2.7 2 1 1 3 3 3 2 PQ loop repeat IgaA PF07095.11 EKX34188.1 - 2 6.3 4.5 7.5 4.4 0.8 2.1 1 1 1 2 2 2 0 Intracellular growth attenuator protein IgaA LRAT PF04970.13 EKX34189.1 - 1e-06 29.1 0.3 2.7e-06 27.7 0.3 1.8 1 1 0 1 1 1 1 Lecithin retinol acyltransferase CNOT1_HEAT PF16418.5 EKX34190.1 - 0.092 12.8 0.3 0.14 12.3 0.3 1.2 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Rubis-subs-bind PF09273.11 EKX34191.1 - 4.7e-14 53.2 2.3 1.2e-13 51.8 2.3 1.7 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 EKX34191.1 - 8.4e-09 36.0 0.2 3.3e-08 34.1 0.0 2.0 2 1 0 2 2 2 1 SET domain PerC PF06069.11 EKX34191.1 - 0.11 12.8 1.4 0.36 11.1 1.4 1.8 1 0 0 1 1 1 0 PerC transcriptional activator NAP PF00956.18 EKX34192.1 - 2.4e-44 151.5 17.0 2.7e-26 92.4 0.0 4.0 3 1 1 4 4 4 3 Nucleosome assembly protein (NAP) DUF4407 PF14362.6 EKX34192.1 - 0.36 10.1 0.9 20 4.4 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) PAC1 PF16094.5 EKX34192.1 - 0.46 9.6 2.9 0.93 8.6 2.9 1.4 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 CDC45 PF02724.14 EKX34192.1 - 0.97 7.7 8.5 1.7 6.8 8.5 1.3 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.8 EKX34192.1 - 2.1 8.6 17.7 0.32 11.2 8.8 2.5 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 FAM176 PF14851.6 EKX34192.1 - 2.4 7.8 11.4 7.1 6.3 8.0 2.4 2 0 0 2 2 2 0 FAM176 family Astro_capsid_p PF12226.8 EKX34192.1 - 4.4 6.3 11.6 7.2 5.6 11.6 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DNA_pol_phi PF04931.13 EKX34192.1 - 4.9 5.1 18.9 10 4.0 18.9 1.5 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 EKX34192.1 - 7.4 5.9 21.2 3.9 6.8 12.7 2.1 2 0 0 2 2 2 0 SDA1 PseudoU_synth_1 PF01416.20 EKX34193.1 - 8.3e-17 61.6 0.0 1.2e-12 48.2 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase Sod_Ni PF09055.11 EKX34194.1 - 0.16 12.5 7.1 0.13 12.8 1.1 2.8 2 1 1 3 3 3 0 Nickel-containing superoxide dismutase DASH_Spc34 PF08657.10 EKX34194.1 - 2.1 8.1 4.8 7.9 6.2 0.1 2.3 2 0 0 2 2 2 0 DASH complex subunit Spc34 Presenilin PF01080.17 EKX34195.1 - 1.8 7.3 3.2 2.4 6.8 3.2 1.2 1 0 0 1 1 1 0 Presenilin DDRGK PF09756.9 EKX34195.1 - 6.7 6.3 18.1 2.4 7.7 8.8 2.2 2 0 0 2 2 2 0 DDRGK domain SURF6 PF04935.12 EKX34197.1 - 8.2e-12 45.3 64.1 8.2e-12 45.3 64.1 4.1 1 1 1 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 EKX34197.1 - 0.00039 21.0 1.3 0.00039 21.0 1.3 6.8 5 2 1 6 6 6 1 60S ribosome biogenesis protein Rrp14 CENP-B_dimeris PF09026.10 EKX34197.1 - 1.9 8.9 5.7 23 5.5 3.0 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Aminotran_4 PF01063.19 EKX34198.1 - 1.6e-48 165.5 0.0 2.8e-48 164.7 0.0 1.4 1 0 0 1 1 1 1 Amino-transferase class IV Sulfotransfer_3 PF13469.6 EKX34198.1 - 0.0001 22.7 0.1 0.00054 20.4 0.0 2.3 2 1 0 2 2 2 1 Sulfotransferase family PDZ_3 PF17815.1 EKX34198.1 - 0.0011 18.9 0.0 0.0034 17.3 0.0 1.8 1 0 0 1 1 1 1 PDZ domain 3HCDH_N PF02737.18 EKX34198.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2358 PF10184.9 EKX34199.1 - 4.4e-13 49.5 0.0 6.3e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 EKX34199.1 - 0.0004 21.0 0.0 0.0032 18.1 0.0 2.0 2 0 0 2 2 2 1 SnoaL-like domain AAA PF00004.29 EKX34200.1 - 1.1e-31 110.0 0.0 1.9e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EKX34200.1 - 7.9e-08 32.7 0.4 5.6e-07 29.9 0.1 2.3 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 EKX34200.1 - 2e-07 31.5 0.2 7.8e-07 29.6 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EKX34200.1 - 5.3e-06 26.1 0.2 0.028 14.0 0.0 2.3 1 1 1 2 2 2 2 AAA domain ATPase_2 PF01637.18 EKX34200.1 - 1.6e-05 24.9 0.3 0.0032 17.4 0.3 2.2 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 EKX34200.1 - 9.8e-05 22.9 0.0 0.00018 22.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EKX34200.1 - 0.00011 22.4 0.0 0.00016 21.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 EKX34200.1 - 0.00021 21.0 0.0 0.00041 20.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EKX34200.1 - 0.00035 20.8 0.0 0.00072 19.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EKX34200.1 - 0.00035 20.6 0.0 0.00062 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EKX34200.1 - 0.00077 19.3 0.0 0.0027 17.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EKX34200.1 - 0.00078 19.2 0.0 0.0016 18.2 0.0 1.6 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 EKX34200.1 - 0.0011 19.0 0.1 0.002 18.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EKX34200.1 - 0.0011 19.3 0.1 0.0035 17.7 0.0 2.0 2 0 0 2 2 1 1 RNA helicase RuvB_N PF05496.12 EKX34200.1 - 0.0018 18.1 0.0 0.0043 16.8 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 EKX34200.1 - 0.002 18.1 0.2 0.0078 16.1 0.2 2.0 1 1 0 1 1 1 1 NACHT domain Cytidylate_kin PF02224.18 EKX34200.1 - 0.002 17.9 0.1 0.0038 17.0 0.1 1.6 1 1 0 1 1 1 1 Cytidylate kinase KAP_NTPase PF07693.14 EKX34200.1 - 0.0024 17.2 0.0 0.23 10.7 0.0 2.3 1 1 1 2 2 2 2 KAP family P-loop domain DUF815 PF05673.13 EKX34200.1 - 0.0027 16.9 0.0 0.0064 15.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 EKX34200.1 - 0.0033 17.7 0.0 0.0079 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 EKX34200.1 - 0.0034 17.4 0.0 0.0061 16.6 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EKX34200.1 - 0.0044 16.8 0.0 0.013 15.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EKX34200.1 - 0.0047 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.6 EKX34200.1 - 0.0049 17.2 0.3 0.04 14.3 0.3 2.2 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 EKX34200.1 - 0.0072 15.8 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain TIP49 PF06068.13 EKX34200.1 - 0.0096 15.2 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain Rad17 PF03215.15 EKX34200.1 - 0.0099 15.8 0.0 0.025 14.5 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain DUF2075 PF09848.9 EKX34200.1 - 0.01 15.1 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.21 EKX34200.1 - 0.013 14.9 0.0 0.084 12.3 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 EKX34200.1 - 0.015 14.7 0.1 0.56 9.5 0.0 2.4 1 1 1 2 2 2 0 KaiC PhoH PF02562.16 EKX34200.1 - 0.017 14.6 0.0 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 EKX34200.1 - 0.017 14.7 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EKX34200.1 - 0.022 15.3 0.0 0.034 14.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_3 PF07726.11 EKX34200.1 - 0.036 13.9 0.1 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 EKX34200.1 - 0.038 13.8 0.0 0.093 12.5 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.26 EKX34200.1 - 0.077 12.7 0.0 0.2 11.3 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_17 PF13207.6 EKX34200.1 - 0.092 13.2 0.1 0.25 11.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain Sigma54_activ_2 PF14532.6 EKX34200.1 - 0.1 12.7 0.1 0.67 10.1 0.1 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain CPT PF07931.12 EKX34200.1 - 0.12 12.2 0.1 0.53 10.1 0.0 2.1 2 1 0 2 2 1 0 Chloramphenicol phosphotransferase-like protein AAA_13 PF13166.6 EKX34200.1 - 0.14 10.7 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EKX34200.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 EKX34200.1 - 0.17 12.0 0.0 0.51 10.4 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase Forkhead PF00250.18 EKX34201.1 - 3.3e-09 36.9 0.0 6e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 EKX34201.1 - 0.013 15.8 0.1 0.026 14.9 0.1 1.5 1 0 0 1 1 1 0 FHA domain SIS PF01380.22 EKX34202.1 - 3.5e-64 214.5 0.2 4.3e-32 110.7 0.1 2.5 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EKX34202.1 - 3e-23 82.5 0.0 6.3e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EKX34202.1 - 2.1e-14 53.5 0.0 3.4e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EKX34202.1 - 5.2e-05 22.3 0.0 8.8e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 EKX34202.1 - 5.5e-05 23.2 0.0 0.00018 21.5 0.0 1.9 2 0 0 2 2 2 1 SIS domain DUF4920 PF16267.5 EKX34202.1 - 0.008 16.1 0.1 0.15 12.1 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4920) PSK_trans_fac PF07704.11 EKX34202.1 - 0.13 13.0 0.1 0.42 11.4 0.1 1.9 1 0 0 1 1 1 0 Rv0623-like transcription factor HTH_5 PF01022.20 EKX34202.1 - 0.21 11.5 1.5 1 9.3 0.0 2.8 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family Cation_ATPase_C PF00689.21 EKX34203.1 - 3.1e-41 141.1 3.0 1.9e-40 138.5 2.8 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EKX34203.1 - 3.9e-33 114.5 0.0 1.2e-32 112.9 0.0 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 EKX34203.1 - 8.8e-14 51.4 0.0 2.1e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EKX34203.1 - 9.7e-14 52.1 3.4 1.4e-10 41.8 3.4 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EKX34203.1 - 9e-13 47.7 0.0 2.4e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EKX34203.1 - 3.9e-05 23.5 1.7 0.0003 20.6 1.8 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 EKX34204.1 - 1.8e-25 89.8 0.0 1.9e-25 89.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX34204.1 - 5.6e-21 75.0 0.0 6e-21 74.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX34204.1 - 6.9e-08 32.7 0.0 1.1e-07 32.0 0.0 1.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX34204.1 - 9.2e-06 24.7 0.0 1e-05 24.5 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EKX34204.1 - 1.2e-05 24.8 0.0 1.5e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EKX34204.1 - 0.00092 18.3 0.0 0.0011 18.0 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EKX34204.1 - 0.0018 17.7 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EKX34204.1 - 0.023 14.3 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 EKX34204.1 - 0.094 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family DUF1679 PF07914.11 EKX34204.1 - 0.11 11.3 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) APG12 PF04110.13 EKX34206.1 - 5.1e-23 81.3 0.0 6.1e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Ank_4 PF13637.6 EKX34207.1 - 5.8e-13 49.1 0.1 1.8e-08 34.7 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX34207.1 - 1.8e-09 37.7 0.0 3.2e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX34207.1 - 1.2e-07 32.3 0.0 2.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX34207.1 - 5.9e-07 29.6 0.0 1.4e-05 25.3 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EKX34207.1 - 4.2e-05 23.6 0.1 0.012 16.1 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeat Apt1 PF10351.9 EKX34207.1 - 2.6 6.8 7.8 3.4 6.4 7.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain MFS_1 PF07690.16 EKX34208.1 - 1.7e-05 23.9 0.6 2e-05 23.7 0.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily GCS PF03074.16 EKX34209.1 - 1.7e-157 524.5 0.0 2.1e-157 524.2 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.13 EKX34209.1 - 0.021 14.2 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) fn3 PF00041.21 EKX34209.1 - 0.045 14.1 0.1 0.11 12.9 0.1 1.6 1 0 0 1 1 1 0 Fibronectin type III domain S1 PF00575.23 EKX34209.1 - 0.18 12.2 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 S1 RNA binding domain Mito_carr PF00153.27 EKX34210.1 - 0.0007 19.5 5.2 1.7 8.6 0.0 3.8 3 1 0 3 3 3 2 Mitochondrial carrier protein F5_F8_type_C PF00754.25 EKX34211.1 - 0.0049 17.0 0.5 0.0098 16.0 0.5 1.5 1 0 0 1 1 1 1 F5/8 type C domain Salp15 PF12115.8 EKX34211.1 - 0.019 15.4 0.1 0.047 14.1 0.1 1.7 1 0 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation zf-TAZ PF02135.16 EKX34211.1 - 0.17 12.4 2.4 0.57 10.7 2.4 1.9 1 0 0 1 1 1 0 TAZ zinc finger HBM PF16591.5 EKX34213.1 - 0.006 16.0 2.9 0.0063 16.0 1.0 1.8 2 0 0 2 2 2 1 Helical bimodular sensor domain Apolipoprotein PF01442.18 EKX34213.1 - 0.041 13.7 0.4 0.092 12.6 0.2 1.6 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Phage_TAC_4 PF08748.11 EKX34213.1 - 0.045 14.1 0.1 0.37 11.1 0.0 2.2 2 0 0 2 2 2 0 Phage tail assembly chaperone HBM PF16591.5 EKX34214.1 - 0.0057 16.1 3.0 0.0071 15.8 1.1 1.9 2 0 0 2 2 2 1 Helical bimodular sensor domain Apolipoprotein PF01442.18 EKX34214.1 - 0.039 13.8 0.2 0.093 12.6 0.1 1.7 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Phage_TAC_4 PF08748.11 EKX34214.1 - 0.055 13.8 0.1 0.4 11.0 0.0 2.2 2 0 0 2 2 2 0 Phage tail assembly chaperone Aldo_ket_red PF00248.21 EKX34216.1 - 1.3e-61 208.4 0.0 1.5e-61 208.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2774 PF11242.8 EKX34216.1 - 0.029 14.6 0.0 2.2 8.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) polyprenyl_synt PF00348.17 EKX34217.1 - 1.1e-24 86.9 0.0 1.6e-16 60.1 0.0 2.0 2 0 0 2 2 2 2 Polyprenyl synthetase Ank_3 PF13606.6 EKX34218.1 - 4e-26 88.2 0.1 0.0002 21.5 0.1 6.3 5 1 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 EKX34218.1 - 2.6e-24 85.3 0.1 4.1e-07 30.4 0.0 4.8 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX34218.1 - 3e-24 85.4 0.0 3e-09 37.3 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX34218.1 - 5.5e-24 83.9 1.1 1.8e-09 37.7 0.2 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EKX34218.1 - 1.1e-21 76.2 0.6 2.2e-05 24.7 0.3 5.9 6 0 0 6 6 6 3 Ankyrin repeat DHHC PF01529.20 EKX34219.1 - 2.4e-20 73.0 9.7 2.6e-20 72.9 9.7 1.0 1 0 0 1 1 1 1 DHHC palmitoyltransferase IDO PF01231.18 EKX34220.1 - 0.016 14.0 2.0 0.023 13.5 0.1 1.7 1 1 1 2 2 2 0 Indoleamine 2,3-dioxygenase zf-CCHC PF00098.23 EKX34220.1 - 0.88 9.8 7.1 0.16 12.1 2.3 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 EKX34220.1 - 1.4 8.7 4.4 3.3 7.5 4.4 1.6 1 0 0 1 1 1 0 Zinc knuckle Atg14 PF10186.9 EKX34221.1 - 2.1 7.3 8.7 3.4 6.7 1.5 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4140 PF13600.6 EKX34221.1 - 6.1 7.3 9.6 2.7 8.5 2.1 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TipAS PF07739.13 EKX34221.1 - 9.9 6.7 11.3 1.1 9.8 1.2 2.5 2 1 0 2 2 2 0 TipAS antibiotic-recognition domain Ank_5 PF13857.6 EKX34223.1 - 1.3e-08 34.9 0.0 3e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX34223.1 - 1.3e-06 28.9 0.0 0.00011 22.7 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX34223.1 - 4.1e-06 27.3 0.0 1.4e-05 25.5 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX34223.1 - 0.00015 22.0 0.2 0.0006 20.1 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EKX34223.1 - 0.002 18.5 0.0 0.0055 17.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat BNR PF02012.20 EKX34223.1 - 0.0052 16.6 0.2 8 6.9 0.0 3.5 3 0 0 3 3 3 1 BNR/Asp-box repeat Cwf_Cwc_15 PF04889.12 EKX34223.1 - 0.0082 15.9 3.7 0.0082 15.9 3.7 3.4 3 1 0 3 3 3 1 Cwf15/Cwc15 cell cycle control protein Zip PF02535.22 EKX34223.1 - 0.08 12.1 12.0 0.14 11.3 12.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Velvet PF11754.8 EKX34223.1 - 0.19 11.6 8.9 0.32 10.9 8.9 1.5 1 0 0 1 1 1 0 Velvet factor Mucin15 PF15672.5 EKX34224.1 - 0.1 12.1 0.3 0.1 12.1 0.3 1.5 2 0 0 2 2 2 0 Cell-membrane associated Mucin15 DUF2113 PF09886.9 EKX34226.1 - 0.034 13.5 0.4 0.088 12.1 0.4 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2113) HA2 PF04408.23 EKX34227.1 - 1.6e-13 50.9 2.6 9.6e-13 48.4 2.6 2.5 1 1 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EKX34227.1 - 4.1e-12 46.4 0.0 1.6e-11 44.5 0.0 2.0 2 0 0 2 2 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EKX34227.1 - 1.2e-09 38.4 0.0 2.9e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EKX34227.1 - 1.7e-05 24.7 1.0 0.00015 21.6 1.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase TPT PF03151.16 EKX34227.1 - 0.00016 21.1 9.4 0.00072 19.0 4.5 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family AAA_22 PF13401.6 EKX34227.1 - 0.00026 21.3 0.1 0.0012 19.2 0.1 2.2 1 0 0 1 1 1 1 AAA domain Herpes_ori_bp PF02399.15 EKX34227.1 - 0.0043 15.2 0.7 0.0068 14.5 0.7 1.2 1 0 0 1 1 1 1 Origin of replication binding protein ResIII PF04851.15 EKX34227.1 - 0.03 14.3 0.1 0.28 11.2 0.1 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.6 EKX34227.1 - 0.036 14.2 0.1 0.16 12.1 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 EKX34227.1 - 0.038 13.4 0.0 0.092 12.1 0.0 1.6 1 0 0 1 1 1 0 KaiC T2SSE PF00437.20 EKX34227.1 - 0.062 12.3 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 EKX34227.1 - 0.089 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EKX34227.1 - 0.1 13.1 0.3 0.47 11.0 0.0 2.3 2 0 0 2 2 2 0 ABC transporter DUF2201_N PF13203.6 EKX34227.1 - 0.29 10.7 6.7 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 Putative metallopeptidase domain AAA_16 PF13191.6 EKX34227.1 - 1.5 9.2 4.9 1.9 8.8 0.0 3.4 4 0 0 4 4 4 0 AAA ATPase domain SET PF00856.28 EKX34228.1 - 0.00031 21.2 0.0 0.0016 18.9 0.0 1.9 1 1 0 1 1 1 1 SET domain CAF1-p150_N PF15557.6 EKX34235.1 - 0.0013 18.8 0.1 0.0036 17.3 0.0 1.7 1 1 0 1 1 1 1 CAF1 complex subunit p150, region binding to PCNA Retrotrans_gag PF03732.17 EKX34235.1 - 0.0024 18.1 0.0 0.007 16.6 0.0 1.8 1 0 0 1 1 1 1 Retrotransposon gag protein RVP PF00077.20 EKX34235.1 - 0.01 16.1 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 EKX34235.1 - 0.012 16.2 0.0 0.044 14.4 0.0 2.0 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 EKX34235.1 - 0.042 14.4 0.0 0.13 12.9 0.0 1.9 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease ALO PF04030.14 EKX34235.1 - 0.1 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase Gag_p24 PF00607.20 EKX34235.1 - 0.11 12.3 0.1 0.4 10.5 0.0 1.9 2 0 0 2 2 2 0 gag gene protein p24 (core nucleocapsid protein) Sec7 PF01369.20 EKX34239.1 - 1.8e-64 216.8 0.0 2.4e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 Sec7 domain BCNT PF07572.12 EKX34240.1 - 1.2e-16 60.5 6.8 1.2e-16 60.5 6.8 2.9 2 1 1 3 3 3 1 Bucentaur or craniofacial development Phi_1 PF04674.12 EKX34240.1 - 0.072 12.4 1.2 0.12 11.6 1.2 1.3 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region GREB1 PF15782.5 EKX34240.1 - 4.2 4.4 30.0 5.3 4.0 30.0 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer V_ATPase_I PF01496.19 EKX34241.1 - 0.25 9.2 3.4 0.093 10.6 1.1 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Folate_carrier PF01770.18 EKX34241.1 - 0.35 9.6 0.1 0.52 9.0 0.1 1.2 1 0 0 1 1 1 0 Reduced folate carrier Usp PF00582.26 EKX34241.1 - 2.5 8.6 7.5 2.4 8.7 6.4 1.7 1 1 0 1 1 1 0 Universal stress protein family U79_P34 PF03064.16 EKX34241.1 - 2.9 7.2 17.3 5.2 6.4 17.3 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Presenilin PF01080.17 EKX34241.1 - 8 5.1 10.2 9 4.9 10.2 1.3 1 0 0 1 1 1 0 Presenilin E1-E2_ATPase PF00122.20 EKX34242.1 - 5.1e-49 166.2 6.1 5.1e-49 166.2 6.1 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EKX34242.1 - 1e-40 139.4 2.6 1e-40 139.4 2.6 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EKX34242.1 - 1.5e-21 77.6 0.3 1.6e-17 64.5 0.1 2.8 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EKX34242.1 - 7.2e-19 67.3 0.0 1.4e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EKX34242.1 - 5.7e-15 55.2 0.0 1.2e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EKX34242.1 - 4.7e-05 23.2 0.6 0.00048 19.9 0.5 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4795 PF16043.5 EKX34243.1 - 0.00094 18.8 11.5 0.041 13.5 1.9 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4795) CENP-F_leu_zip PF10473.9 EKX34243.1 - 0.0026 17.8 6.8 0.018 15.0 7.0 2.1 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RNase_E_G PF10150.9 EKX34243.1 - 0.003 17.0 3.0 0.0041 16.6 3.0 1.2 1 0 0 1 1 1 1 Ribonuclease E/G family SWIB PF02201.18 EKX34243.1 - 0.047 13.6 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 SWIB/MDM2 domain ACP_PD PF04336.12 EKX34243.1 - 0.08 13.4 0.9 0.56 10.7 0.9 2.4 1 1 0 1 1 1 0 Acyl carrier protein phosphodiesterase DUF2808 PF10989.8 EKX34243.1 - 0.13 12.3 0.1 0.18 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) Phasin PF05597.11 EKX34243.1 - 0.16 12.0 3.4 0.3 11.1 3.0 1.7 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) bZIP_1 PF00170.21 EKX34243.1 - 0.28 11.3 3.0 0.73 10.0 0.3 2.7 1 1 2 3 3 3 0 bZIP transcription factor Fib_alpha PF08702.10 EKX34243.1 - 0.71 10.1 5.3 1.1 9.5 5.3 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 EKX34243.1 - 1.5 8.7 6.4 0.69 9.7 1.2 2.5 2 1 0 2 2 2 0 Septum formation initiator TSNAXIP1_N PF15739.5 EKX34243.1 - 3.4 8.1 8.7 6.9 7.1 0.7 2.4 1 1 0 2 2 2 0 Translin-associated factor X-interacting N-terminus peroxidase PF00141.23 EKX34249.1 - 2.4e-10 40.5 0.0 3.2e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Peroxidase SNF2_N PF00176.23 EKX34252.1 - 6.9e-71 238.8 0.2 1.3e-70 237.9 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.6 EKX34252.1 - 5.4e-09 36.3 12.1 5.4e-09 36.3 12.1 2.3 2 0 0 2 2 1 1 Ring finger domain Helicase_C PF00271.31 EKX34252.1 - 7e-09 36.0 0.0 2.4e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 EKX34252.1 - 5.8e-07 29.4 9.8 1.8e-06 27.8 9.8 1.9 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EKX34252.1 - 1.9e-05 24.4 9.5 4.4e-05 23.3 9.5 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EKX34252.1 - 0.00033 20.6 5.5 0.00053 19.9 4.4 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EKX34252.1 - 0.00063 19.5 12.1 0.00063 19.5 12.1 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EKX34252.1 - 0.005 16.9 2.8 0.013 15.5 2.8 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 EKX34252.1 - 0.0056 16.5 11.0 0.017 15.0 11.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 EKX34252.1 - 0.0056 16.5 1.9 0.19 11.6 0.1 2.8 2 0 0 2 2 2 1 Rad50 zinc hook motif FYDLN_acid PF09538.10 EKX34252.1 - 0.015 16.0 1.8 0.015 16.0 1.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-rbx1 PF12678.7 EKX34252.1 - 0.046 14.0 9.0 0.036 14.4 6.1 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EKX34252.1 - 0.055 13.2 14.6 0.024 14.4 11.5 2.1 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_4 PF14570.6 EKX34252.1 - 0.062 13.1 9.9 0.14 12.0 9.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Toprim_2 PF13155.6 EKX34252.1 - 0.13 12.7 1.1 8.3 6.9 0.2 3.3 3 0 0 3 3 3 0 Toprim-like Rtf2 PF04641.12 EKX34252.1 - 0.25 10.7 11.0 0.098 12.0 8.0 1.8 2 0 0 2 2 2 0 Rtf2 RING-finger zf-C3HC4_4 PF15227.6 EKX34252.1 - 1.8 8.8 12.1 7.3 6.8 12.1 2.2 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1682 PF07946.14 EKX34252.1 - 6 6.0 9.2 3.2 6.9 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) PH PF00169.29 EKX34253.1 - 1.1e-16 61.2 0.4 1.3e-16 61.0 0.4 1.0 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EKX34253.1 - 1.6e-05 25.3 4.7 0.00038 20.8 4.7 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 EKX34253.1 - 0.007 16.6 0.9 0.013 15.8 0.9 1.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 EKX34253.1 - 0.028 14.2 0.1 0.029 14.2 0.1 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain PH_9 PF15410.6 EKX34253.1 - 0.069 13.5 1.0 0.67 10.3 1.0 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain DSPc PF00782.20 EKX34254.1 - 0.00019 21.3 0.0 0.00029 20.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EKX34254.1 - 0.00023 21.2 0.2 0.00034 20.7 0.2 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EKX34254.1 - 0.00044 19.9 0.0 0.00055 19.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX34254.1 - 0.0042 17.2 0.0 0.0058 16.8 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.12 EKX34254.1 - 0.077 12.7 0.1 0.22 11.2 0.1 1.7 1 1 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase2 PF03162.13 EKX34254.1 - 0.13 11.8 0.5 2.1 7.9 0.1 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family TBP PF00352.21 EKX34255.1 - 4.5e-15 55.4 0.0 4.3e-11 42.6 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) FlgH PF02107.16 EKX34255.1 - 0.03 13.9 0.1 0.039 13.6 0.1 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein MEDS PF14417.6 EKX34255.1 - 0.047 13.5 0.0 0.071 12.9 0.0 1.2 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain TBP PF00352.21 EKX34256.1 - 2.2e-15 56.4 0.0 4.3e-11 42.6 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) FlgH PF02107.16 EKX34256.1 - 0.03 13.9 0.1 0.039 13.6 0.1 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein MEDS PF14417.6 EKX34256.1 - 0.047 13.5 0.0 0.071 12.9 0.0 1.2 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain TBP PF00352.21 EKX34257.1 - 2.1e-15 56.4 0.0 4.3e-11 42.6 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) FlgH PF02107.16 EKX34257.1 - 0.036 13.7 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein MEDS PF14417.6 EKX34257.1 - 0.046 13.5 0.0 0.071 12.9 0.0 1.2 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain TBP PF00352.21 EKX34258.1 - 2.1e-15 56.4 0.0 4.3e-11 42.6 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) FlgH PF02107.16 EKX34258.1 - 0.036 13.7 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein MEDS PF14417.6 EKX34258.1 - 0.046 13.5 0.0 0.071 12.9 0.0 1.2 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain REJ PF02010.15 EKX34259.1 - 1.4e-25 90.0 4.4 6e-25 87.9 2.1 2.3 1 1 0 2 2 2 2 REJ domain Ephrin_rec_like PF07699.13 EKX34260.1 - 4.7e-36 122.3 91.0 3.5e-06 26.7 3.3 10.9 3 3 5 9 9 9 9 Putative ephrin-receptor like NCD3G PF07562.14 EKX34260.1 - 1.6e-19 69.6 61.8 6.5e-05 22.8 0.3 9.2 4 2 3 8 8 8 8 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX34260.1 - 0.00019 21.7 64.5 0.17 12.3 1.8 11.5 3 3 10 13 13 13 9 TNFR/NGFR cysteine-rich region Reovirus_L2 PF06016.11 EKX34260.1 - 0.17 9.1 4.0 2.5 5.2 0.1 2.7 2 1 1 3 3 3 0 Reovirus core-spike protein lambda-2 (L2) PSGP PF07276.11 EKX34260.1 - 3.3 8.3 8.0 86 3.9 0.5 4.2 3 0 0 3 3 3 0 Apopolysialoglycoprotein (PSGP) EGF_MSP1_1 PF12946.7 EKX34260.1 - 4.6 7.4 22.3 10 6.2 1.2 6.5 5 1 0 5 5 5 0 MSP1 EGF domain 1 DUF995 PF06191.12 EKX34260.1 - 4.9 6.8 6.5 56 3.4 0.4 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF995) Laminin_G_3 PF13385.6 EKX34261.1 - 7.7e-20 71.6 8.8 2.4e-19 70.0 8.8 1.9 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Ephrin_rec_like PF07699.13 EKX34261.1 - 2.1e-07 30.6 29.3 0.00033 20.3 4.6 4.7 3 1 1 4 4 4 3 Putative ephrin-receptor like Toxin_R_bind_N PF07953.12 EKX34261.1 - 0.025 14.3 5.0 0.045 13.5 5.0 1.3 1 0 0 1 1 1 0 Clostridium neurotoxin, N-terminal receptor binding SmpA_OmlA PF04355.13 EKX34261.1 - 0.23 11.3 1.0 0.38 10.6 0.2 1.8 2 0 0 2 2 2 0 SmpA / OmlA family RICTOR_V PF14668.6 EKX34262.1 - 0.013 15.7 53.9 25 5.2 0.5 10.4 10 0 0 10 10 10 0 Rapamycin-insensitive companion of mTOR, domain 5 AID PF18767.1 EKX34263.1 - 0.11 12.5 0.0 0.11 12.5 0.0 1.0 1 0 0 1 1 1 0 Activation induced deaminase Engrail_1_C_sig PF10525.9 EKX34263.1 - 0.16 11.3 0.3 0.24 10.7 0.3 1.3 1 0 0 1 1 1 0 Engrailed homeobox C-terminal signature domain PPDK_N PF01326.19 EKX34264.1 - 1e-22 80.9 0.0 1.7e-17 63.7 0.0 4.3 2 1 0 2 2 2 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain BAR_3 PF16746.5 EKX34264.1 - 0.04 13.6 0.1 0.08 12.6 0.1 1.4 1 0 0 1 1 1 0 BAR domain of APPL family Sushi PF00084.20 EKX34265.1 - 7.4e-13 48.9 66.7 0.0025 18.4 0.1 17.4 19 2 1 20 20 20 8 Sushi repeat (SCR repeat) ZU5 PF00791.20 EKX34265.1 - 3.4e-07 30.5 0.0 1.1e-06 28.8 0.0 2.0 1 0 0 1 1 1 1 ZU5 domain Guanylate_cyc PF00211.20 EKX34266.1 - 1.9e-09 37.4 0.0 2.3e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LAP1C PF05609.12 EKX34269.1 - 6.5 5.7 29.8 10 5.1 29.8 1.4 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) NPBW PF15180.6 EKX34270.1 - 0.28 11.0 1.2 0.32 10.8 0.2 1.6 1 1 1 2 2 2 0 Neuropeptides B and W DHR10 PF18595.1 EKX34271.1 - 0.019 15.0 7.5 0.019 15.0 7.5 4.2 2 1 2 4 4 4 0 Designed helical repeat protein 10 domain T3SS_needle_E PF08988.10 EKX34271.1 - 0.034 14.3 0.9 0.034 14.3 0.9 3.7 3 1 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle DPM3 PF08285.11 EKX34271.1 - 0.33 11.2 1.6 0.88 9.8 0.7 2.2 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Spc7 PF08317.11 EKX34271.1 - 1 8.2 36.7 0.21 10.4 20.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 EKX34271.1 - 5.4 7.0 37.3 0.8 9.7 17.2 3.4 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 EKX34271.1 - 5.5 6.3 35.7 2.8 7.2 15.8 2.4 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Pkinase PF00069.25 EKX34273.1 - 1e-47 162.7 0.0 1.2e-47 162.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX34273.1 - 5e-38 130.9 0.0 6.6e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX34273.1 - 4.6e-06 25.7 0.0 7.9e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EKX34273.1 - 0.00062 19.2 0.0 0.00092 18.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EKX34273.1 - 0.0026 17.7 0.1 0.96 9.3 0.0 2.3 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EKX34273.1 - 0.033 13.5 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PDZ_6 PF17820.1 EKX34274.1 - 1.1e-08 34.8 0.0 3.3e-08 33.2 0.0 2.0 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX34274.1 - 4.3e-06 27.0 0.0 1.2e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX34274.1 - 0.00012 22.4 0.0 0.00033 21.0 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX34274.1 - 0.013 15.4 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain GRASP55_65 PF04495.14 EKX34274.1 - 0.016 15.5 0.0 0.033 14.5 0.0 1.4 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Ank_4 PF13637.6 EKX34277.1 - 7.6e-23 80.6 0.7 5.5e-13 49.1 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX34277.1 - 1.7e-20 72.8 2.6 3.5e-08 33.5 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX34277.1 - 1.9e-18 66.8 0.1 4.8e-11 43.1 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EKX34277.1 - 8.9e-16 57.5 3.4 1.7e-07 31.4 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 EKX34277.1 - 3.2e-13 48.5 0.1 3.5e-05 23.9 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Lum_binding PF00677.17 EKX34278.1 - 4.5e-05 23.3 0.0 6.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Lumazine binding domain Guanylate_cyc PF00211.20 EKX34280.1 - 8.9e-17 61.3 0.1 1.1e-16 61.0 0.1 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 EKX34281.1 - 1.3e-22 80.3 0.3 1.4e-22 80.2 0.3 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain TCP PF03634.13 EKX34283.1 - 0.06 13.9 0.4 0.091 13.3 0.4 1.6 1 1 0 1 1 1 0 TCP family transcription factor Spc7 PF08317.11 EKX34284.1 - 0.00037 19.5 2.3 0.00056 18.9 2.3 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Lebercilin PF15619.6 EKX34284.1 - 0.00085 19.0 0.3 0.0012 18.5 0.3 1.2 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease COG5 PF10392.9 EKX34284.1 - 0.001 19.2 5.7 0.0054 16.9 5.7 2.0 1 1 0 1 1 1 1 Golgi transport complex subunit 5 Atg14 PF10186.9 EKX34284.1 - 0.0041 16.3 1.0 0.0049 16.0 1.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 BLOC1_2 PF10046.9 EKX34284.1 - 0.0071 16.6 12.2 0.18 12.1 2.2 3.7 1 1 2 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3584 PF12128.8 EKX34284.1 - 0.0072 13.9 2.6 0.0085 13.7 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Prefoldin PF02996.17 EKX34284.1 - 0.013 15.4 9.7 0.17 11.8 0.8 3.7 2 1 3 5 5 5 0 Prefoldin subunit ATG16 PF08614.11 EKX34284.1 - 0.016 15.4 5.2 0.059 13.6 4.9 2.0 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF641 PF04859.12 EKX34284.1 - 0.02 15.2 1.6 1.5 9.1 0.3 2.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) AIP3 PF03915.13 EKX34284.1 - 0.022 13.9 3.0 0.032 13.3 3.0 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 FlaC_arch PF05377.11 EKX34284.1 - 0.037 14.4 6.7 0.34 11.3 0.4 3.5 3 1 1 4 4 3 0 Flagella accessory protein C (FlaC) MscS_porin PF12795.7 EKX34284.1 - 0.04 13.5 12.2 0.059 12.9 12.2 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Cas6b_N PF17955.1 EKX34284.1 - 0.074 13.2 0.3 0.26 11.4 0.1 2.0 2 0 0 2 2 2 0 Cas6b N-terminal domain ADIP PF11559.8 EKX34284.1 - 0.1 12.7 10.2 0.11 12.5 5.1 2.6 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding Filament PF00038.21 EKX34284.1 - 0.12 12.0 4.7 0.22 11.1 4.7 1.4 1 1 0 1 1 1 0 Intermediate filament protein DUF5082 PF16888.5 EKX34284.1 - 0.12 12.6 13.7 0.033 14.5 10.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DUF848 PF05852.11 EKX34284.1 - 0.14 12.3 1.2 0.26 11.4 1.0 1.6 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) ZapB PF06005.12 EKX34284.1 - 0.14 12.6 1.0 0.52 10.8 0.2 2.1 2 0 0 2 2 2 0 Cell division protein ZapB DUF16 PF01519.16 EKX34284.1 - 0.16 12.4 5.1 1.1 9.7 3.1 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 EKX34284.1 - 0.2 11.8 12.6 0.027 14.6 4.8 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family MitMem_reg PF13012.6 EKX34284.1 - 0.22 11.9 7.5 1.3 9.4 3.3 3.0 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function TMF_DNA_bd PF12329.8 EKX34284.1 - 0.27 11.2 2.5 1.2 9.2 0.3 2.4 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Rab5-bind PF09311.11 EKX34284.1 - 0.39 10.1 4.6 1.1 8.6 1.5 2.1 1 1 1 2 2 2 0 Rabaptin-like protein GCN5L1 PF06320.13 EKX34284.1 - 0.52 10.5 5.4 1.1 9.5 2.9 2.5 2 1 1 3 3 3 0 GCN5-like protein 1 (GCN5L1) DUF1664 PF07889.12 EKX34284.1 - 0.92 9.6 8.9 1.7 8.7 0.7 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.11 EKX34284.1 - 2.3 8.8 9.5 2.1 8.9 4.0 2.7 2 1 1 3 3 3 0 Syntaxin 6, N-terminal XhlA PF10779.9 EKX34284.1 - 4 7.7 9.4 13 6.1 0.7 2.8 1 1 1 2 2 2 0 Haemolysin XhlA RWP-RK PF02042.15 EKX34285.1 - 2e-16 59.7 0.1 2.9e-16 59.2 0.1 1.2 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX34285.1 - 0.053 13.3 0.3 9 6.2 0.1 2.5 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family HTH_Tnp_ISL3 PF13542.6 EKX34285.1 - 0.12 11.8 0.0 0.26 10.8 0.0 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 GntR PF00392.21 EKX34285.1 - 0.13 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_6 PF01418.17 EKX34285.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Ephrin_rec_like PF07699.13 EKX34287.1 - 2.2e-49 165.0 144.9 4.9e-10 39.0 9.2 11.3 7 3 4 11 11 11 11 Putative ephrin-receptor like NCD3G PF07562.14 EKX34287.1 - 2.2e-08 33.9 108.7 0.0068 16.3 1.5 12.5 5 2 9 16 16 16 11 Nine Cysteines Domain of family 3 GPCR EGF_MSP1_1 PF12946.7 EKX34287.1 - 9.9e-05 22.3 20.4 0.91 9.6 0.4 7.2 5 1 0 5 5 5 3 MSP1 EGF domain 1 TNFR_c6 PF00020.18 EKX34287.1 - 0.0011 19.3 96.3 0.4 11.1 0.0 15.2 5 4 9 14 14 14 7 TNFR/NGFR cysteine-rich region DDE_Tnp_4 PF13359.6 EKX34290.1 - 1.7e-12 47.3 0.0 2.5e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 EKX34290.1 - 7e-06 25.8 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein Response_reg PF00072.24 EKX34291.1 - 1.9e-16 60.2 0.1 5.7e-12 45.8 0.0 2.9 2 0 0 2 2 2 2 Response regulator receiver domain Guanylate_cyc PF00211.20 EKX34291.1 - 0.04 13.5 0.0 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 Adenylate and Guanylate cyclase catalytic domain Fasciclin PF02469.22 EKX34291.1 - 0.17 12.1 1.8 0.38 11.0 1.8 1.6 1 0 0 1 1 1 0 Fasciclin domain V_ATPase_I PF01496.19 EKX34291.1 - 0.2 9.5 10.7 0.28 9.0 10.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MutS_II PF05188.17 EKX34291.1 - 1.6 9.0 4.9 1.7 8.9 3.0 2.1 2 0 0 2 2 2 0 MutS domain II TCP PF03634.13 EKX34291.1 - 3.1 8.3 0.0 3.1 8.3 0.0 2.8 2 1 0 2 2 2 0 TCP family transcription factor FapA PF03961.13 EKX34291.1 - 9.2 4.7 10.9 14 4.2 10.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Response_reg PF00072.24 EKX34292.1 - 1.2e-28 99.5 0.0 2.4e-28 98.6 0.0 1.5 2 0 0 2 2 2 1 Response regulator receiver domain WD40_like PF17005.5 EKX34293.1 - 0.011 15.0 0.5 0.023 14.0 0.5 1.4 1 0 0 1 1 1 0 WD40-like domain TAF PF02969.17 EKX34293.1 - 0.036 14.2 0.1 2.3 8.5 0.0 3.0 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) DUF4214 PF13946.6 EKX34293.1 - 0.06 13.4 0.2 0.3 11.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4214) ApoO PF09769.9 EKX34293.1 - 0.13 12.2 6.3 0.091 12.7 0.7 3.2 3 0 0 3 3 3 0 Apolipoprotein O DUF3877 PF12993.7 EKX34293.1 - 2.9 7.7 13.3 3.6 7.4 0.4 4.2 3 2 1 4 4 4 0 Domain of unknown function, E. rectale Gene description (DUF3877) DUF4215 PF13948.6 EKX34294.1 - 5.7e-05 23.5 4.8 5.7e-05 23.5 4.8 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4215) ZU5 PF00791.20 EKX34294.1 - 0.03 14.7 0.3 0.19 12.1 0.0 2.3 2 0 0 2 2 2 0 ZU5 domain Dicty_REP PF05086.12 EKX34294.1 - 0.051 11.6 0.3 0.07 11.1 0.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein LYRIC PF15686.5 EKX34294.1 - 0.063 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family SSP160 PF06933.11 EKX34294.1 - 2.8 6.0 18.5 0.53 8.4 14.4 1.7 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Guanylate_cyc PF00211.20 EKX34295.1 - 2.4e-26 92.5 0.0 2.7e-26 92.3 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 EKX34296.1 - 5.7e-24 84.7 0.1 6.3e-24 84.6 0.1 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain TPR_12 PF13424.6 EKX34297.1 - 5.2e-51 170.8 18.9 2.7e-14 53.2 1.4 5.7 3 2 2 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 EKX34297.1 - 1.4e-48 161.5 18.5 7.2e-09 35.2 0.0 9.1 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX34297.1 - 9.5e-22 77.8 10.0 3.5e-10 39.8 4.1 3.2 1 1 2 3 3 3 3 MalT-like TPR region TPR_7 PF13176.6 EKX34297.1 - 7.2e-19 66.4 21.1 0.035 14.1 0.5 9.0 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 EKX34297.1 - 3.3e-14 51.8 18.2 0.33 11.2 0.5 9.1 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX34297.1 - 3.7e-13 49.9 18.7 0.022 15.4 0.4 7.3 5 2 0 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 EKX34297.1 - 1.1e-12 47.6 19.0 0.03 15.1 0.0 8.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX34297.1 - 1.2e-12 48.1 20.8 0.027 15.0 1.8 8.3 4 4 5 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 EKX34297.1 - 1.3e-12 47.0 12.6 0.51 10.3 0.0 9.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX34297.1 - 3.6e-12 45.5 15.5 0.15 12.3 0.0 9.0 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_4 PF07721.14 EKX34297.1 - 1.2e-11 44.1 10.2 4.3 8.3 0.0 8.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_20 PF14561.6 EKX34297.1 - 1.8e-07 31.4 16.0 0.037 14.4 0.1 7.7 2 2 7 9 9 9 2 Tetratricopeptide repeat TPR_3 PF07720.12 EKX34297.1 - 3e-06 27.1 6.0 0.22 11.6 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX34297.1 - 1.1e-05 25.6 3.7 5.7 7.2 0.1 6.0 2 2 4 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 RPN6_N PF18055.1 EKX34297.1 - 0.00017 21.9 7.8 0.66 10.4 0.0 4.5 4 1 1 5 5 5 2 26S proteasome regulatory subunit RPN6 N-terminal domain PPR PF01535.20 EKX34297.1 - 0.00035 20.6 5.9 17 6.0 0.1 6.8 7 0 0 7 7 7 0 PPR repeat Coatomer_E PF04733.14 EKX34297.1 - 0.0024 17.3 5.0 6 6.2 0.0 5.0 2 1 3 5 5 5 1 Coatomer epsilon subunit TPR_17 PF13431.6 EKX34297.1 - 0.0095 16.2 9.9 19 5.9 0.2 6.6 8 0 0 8 8 7 0 Tetratricopeptide repeat RPN7 PF10602.9 EKX34297.1 - 0.041 13.6 1.3 18 4.9 0.0 4.6 4 1 0 4 4 4 0 26S proteasome subunit RPN7 TPR_21 PF09976.9 EKX34297.1 - 0.041 13.6 10.8 29 4.3 0.7 5.5 2 2 4 6 6 6 0 Tetratricopeptide repeat-like domain HTH_18 PF12833.7 EKX34297.1 - 0.18 12.1 0.7 2.4 8.5 0.1 2.7 3 0 0 3 3 2 0 Helix-turn-helix domain TPR_6 PF13174.6 EKX34297.1 - 2.4 9.0 10.7 39 5.2 0.5 6.5 9 0 0 9 9 7 0 Tetratricopeptide repeat TAF8_C PF10406.9 EKX34298.1 - 0.076 13.6 5.1 0.56 10.8 5.1 2.0 1 1 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term IL10 PF00726.17 EKX34299.1 - 0.06 12.8 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Interleukin 10 Retinin_C PF04527.12 EKX34300.1 - 0.014 15.6 25.2 1.8e+04 -6.3 25.2 3.4 1 1 0 1 1 1 0 Drosophila Retinin like protein CD52 PF15116.6 EKX34300.1 - 1.5 8.9 20.9 28 4.9 0.4 5.5 1 1 5 6 6 6 0 CAMPATH-1 antigen Gln-synt_N PF03951.19 EKX34300.1 - 2.1 8.1 6.5 16 5.3 0.6 2.7 1 1 4 5 5 5 0 Glutamine synthetase, beta-Grasp domain RWP-RK PF02042.15 EKX34306.1 - 3.3e-14 52.6 0.9 6e-14 51.7 0.9 1.4 1 1 0 1 1 1 1 RWP-RK domain SH PF01445.17 EKX34306.1 - 0.099 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Viral small hydrophobic protein RWP-RK PF02042.15 EKX34308.1 - 3.2e-14 52.6 0.9 6e-14 51.7 0.9 1.5 1 1 0 1 1 1 1 RWP-RK domain SH PF01445.17 EKX34308.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Viral small hydrophobic protein Ank_4 PF13637.6 EKX34309.1 - 3.6e-40 135.8 0.0 2.7e-08 34.2 0.0 8.3 5 2 4 9 9 9 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX34309.1 - 1.5e-37 128.0 1.5 5.2e-11 43.0 0.2 5.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX34309.1 - 7.2e-22 77.2 0.0 0.0031 17.8 0.0 8.7 6 2 3 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX34309.1 - 2.6e-18 64.2 0.0 0.16 12.6 0.0 9.2 10 0 0 10 10 10 4 Ankyrin repeat Ank PF00023.30 EKX34309.1 - 5.7e-10 39.2 0.0 1.4 9.5 0.0 7.7 10 0 0 10 10 10 2 Ankyrin repeat Baculo_PEP_N PF04512.12 EKX34309.1 - 7.1e-05 23.1 4.7 0.84 10.0 0.0 5.6 1 1 5 6 6 6 1 Baculovirus polyhedron envelope protein, PEP, N terminus DUF5049 PF16468.5 EKX34309.1 - 8.5e-05 22.4 0.0 10 6.1 0.0 5.8 7 0 0 7 7 7 1 Domain of unknown function (DUF5049) DUF3746 PF12562.8 EKX34309.1 - 0.098 12.6 2.3 11 6.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3746) Dmrt1 PF12374.8 EKX34309.1 - 0.5 10.8 8.0 24 5.4 0.0 5.5 6 0 0 6 6 6 0 Double-sex mab3 related transcription factor 1 Ins_beta PF03488.14 EKX34309.1 - 0.74 9.9 11.7 15 5.7 0.4 5.3 6 1 0 6 6 6 0 Nematode insulin-related peptide beta type TPR_1 PF00515.28 EKX34310.1 - 1.2e-12 47.1 0.0 5.4e-06 26.0 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat STI1 PF17830.1 EKX34310.1 - 6.9e-12 45.1 12.6 3.7e-11 42.8 9.9 2.5 2 0 0 2 2 2 1 STI1 domain TPR_2 PF07719.17 EKX34310.1 - 4.2e-11 42.1 0.0 0.0094 16.0 0.0 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat HipN PF18253.1 EKX34310.1 - 8.4e-05 22.2 0.0 0.00027 20.5 0.0 1.9 1 0 0 1 1 1 1 Hsp70-interacting protein N N-terminal domain TPR_16 PF13432.6 EKX34310.1 - 9.9e-05 22.9 0.0 0.34 11.6 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX34310.1 - 0.00011 22.3 0.0 0.001 19.3 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX34310.1 - 0.001 19.2 0.0 0.0026 17.9 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX34310.1 - 0.0075 16.7 0.1 0.6 10.7 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX34310.1 - 0.014 15.0 0.0 0.095 12.4 0.0 2.4 2 0 0 2 2 2 0 TPR repeat TPR_6 PF13174.6 EKX34310.1 - 0.029 15.0 0.1 67 4.4 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF5523 PF17661.1 EKX34310.1 - 2.5 7.7 21.8 2.2 7.9 2.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5523) DUF4407 PF14362.6 EKX34310.1 - 2.8 7.2 11.8 0.84 8.9 6.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF1266 PF06889.11 EKX34310.1 - 2.9 7.9 7.2 0.98 9.4 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) Atg14 PF10186.9 EKX34310.1 - 3.2 6.8 9.5 5.2 6.0 9.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MAS20 PF02064.15 EKX34310.1 - 6.3 6.9 13.6 6.6 6.8 8.9 2.5 2 0 0 2 2 2 0 MAS20 protein import receptor RWP-RK PF02042.15 EKX34311.1 - 5e-05 23.2 0.0 9.6e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain Herpes_LMP1 PF05297.11 EKX34312.1 - 0.025 13.8 2.6 0.029 13.6 2.6 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Atx10homo_assoc PF09759.9 EKX34313.1 - 0.00058 19.8 0.4 0.0015 18.5 0.4 1.7 1 1 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 EKX34313.1 - 0.027 14.7 0.6 20 5.8 0.0 3.8 3 1 1 4 4 4 0 HEAT repeat Arm PF00514.23 EKX34313.1 - 0.054 13.5 0.3 0.19 11.8 0.3 2.0 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat PHINT_rpt PF14882.6 EKX34316.1 - 0.031 14.5 2.1 0.031 14.5 2.1 2.0 1 1 1 2 2 2 0 Phage-integrase repeat unit LRR_6 PF13516.6 EKX34317.1 - 3e-06 26.9 4.0 0.22 11.7 0.0 4.6 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 EKX34317.1 - 0.0027 18.1 2.8 10 6.7 0.0 3.8 2 2 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX34317.1 - 0.2 12.3 9.3 12 6.9 0.0 4.7 4 1 0 4 4 4 0 Leucine Rich Repeat TYW3 PF02676.14 EKX34318.1 - 0.05 13.0 0.1 0.054 12.8 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase TYW3 RWP-RK PF02042.15 EKX34319.1 - 2.4e-16 59.4 0.4 4.3e-16 58.6 0.4 1.4 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX34320.1 - 2.2e-16 59.5 0.4 4.3e-16 58.6 0.4 1.5 1 0 0 1 1 1 1 RWP-RK domain TNFR_c6 PF00020.18 EKX34321.1 - 0.002 18.5 3.6 0.002 18.5 3.6 9.5 7 3 4 11 11 11 3 TNFR/NGFR cysteine-rich region Consortin_C PF15281.6 EKX34321.1 - 0.066 13.2 0.7 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 Consortin C-terminus zf-C3HC4_3 PF13920.6 EKX34322.1 - 2.8e-09 36.7 10.6 2.8e-09 36.7 10.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF5633 PF18656.1 EKX34322.1 - 0.25 11.2 0.4 0.62 10.0 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5633) Thioredoxin PF00085.20 EKX34323.1 - 0.12 12.3 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin WD40 PF00400.32 EKX34324.1 - 2.6e-36 123.0 28.1 2.4e-05 25.0 0.2 11.5 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX34324.1 - 3.5e-09 36.8 0.7 0.0058 16.9 0.0 5.4 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EKX34324.1 - 1.3e-08 34.5 0.1 0.018 14.4 0.0 4.3 4 2 0 4 4 4 3 WD40-like domain Cytochrom_D1 PF02239.16 EKX34324.1 - 0.0032 16.0 0.2 0.53 8.8 0.2 3.2 2 1 0 3 3 3 1 Cytochrome D1 heme domain BBS2_Mid PF14783.6 EKX34324.1 - 0.0035 17.4 0.0 0.021 14.9 0.0 2.3 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Kelch_6 PF13964.6 EKX34324.1 - 0.0083 16.4 8.2 0.81 10.1 0.0 5.7 7 0 0 7 7 7 1 Kelch motif PQQ PF01011.21 EKX34324.1 - 0.034 14.1 0.1 0.23 11.4 0.1 2.4 2 0 0 2 2 2 0 PQQ enzyme repeat FAA_hydrolase PF01557.18 EKX34325.1 - 2.6e-05 24.0 0.0 3.4e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF1459 PF07312.11 EKX34325.1 - 0.056 13.7 0.4 0.092 13.0 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1459) RWP-RK PF02042.15 EKX34326.1 - 0.014 15.3 0.1 0.035 14.1 0.1 1.6 1 0 0 1 1 1 0 RWP-RK domain LRR_4 PF12799.7 EKX34327.1 - 0.09 13.2 0.4 0.17 12.4 0.4 1.5 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX34328.1 - 7.2e-17 60.9 9.9 6.1e-10 38.7 1.5 2.3 1 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EKX34328.1 - 9.6e-12 44.9 15.9 1.2e-05 25.6 0.8 3.6 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EKX34328.1 - 6.7e-07 28.9 12.9 0.028 14.5 0.1 4.4 4 0 0 4 4 4 3 Leucine Rich repeat LRR_1 PF00560.33 EKX34328.1 - 1.6e-06 27.8 9.7 0.7 10.7 0.0 5.1 4 1 0 4 4 4 3 Leucine Rich Repeat LRR_9 PF14580.6 EKX34328.1 - 0.00022 20.8 1.1 0.0015 18.1 0.8 1.9 1 1 0 1 1 1 1 Leucine-rich repeat Guanylate_cyc PF00211.20 EKX34329.1 - 2.1e-32 112.3 0.0 2.4e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Amino_oxidase PF01593.24 EKX34330.1 - 8.2e-55 186.9 0.0 1.1e-54 186.4 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EKX34330.1 - 4.4e-09 36.4 0.0 1.1e-08 35.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EKX34330.1 - 0.0034 17.0 0.0 0.0067 16.0 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EKX34330.1 - 0.035 13.2 0.1 0.082 12.0 0.1 1.5 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 EKX34330.1 - 0.062 12.5 0.1 0.09 12.0 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 EKX34330.1 - 0.07 12.4 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EKX34330.1 - 0.083 12.2 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase CUB PF00431.20 EKX34332.1 - 7.6e-06 26.2 0.0 1.6e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 CUB domain Glutaredoxin PF00462.24 EKX34335.1 - 2.4e-20 72.5 0.1 2.7e-20 72.3 0.1 1.0 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 EKX34335.1 - 0.00035 20.6 0.1 0.00043 20.3 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.14 EKX34335.1 - 0.0007 20.0 0.0 0.0008 19.8 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.6 EKX34335.1 - 0.012 16.0 0.0 0.013 15.9 0.0 1.0 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain SH3BGR PF04908.15 EKX34335.1 - 0.03 14.5 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein DUF1223 PF06764.11 EKX34335.1 - 0.057 13.4 0.0 0.12 12.4 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1223) DUF1848 PF08902.11 EKX34336.1 - 3.7 7.2 4.4 3.3 7.4 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) Arm PF00514.23 EKX34338.1 - 0.11 12.5 0.2 3.5 7.8 0.0 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat EF-hand_7 PF13499.6 EKX34339.1 - 0.0089 16.5 0.2 0.029 14.8 0.2 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX34339.1 - 0.011 15.6 0.1 0.035 14.0 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 EKX34339.1 - 0.059 12.9 0.1 0.24 11.0 0.1 2.0 2 0 0 2 2 2 0 EF hand RWP-RK PF02042.15 EKX34340.1 - 5.6e-12 45.5 0.0 8.5e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX34340.1 - 0.048 13.4 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family SpoIIP PF07454.11 EKX34341.1 - 0.0056 16.2 14.0 0.0063 16.0 14.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) Lin-8 PF03353.15 EKX34341.1 - 0.0072 15.9 14.3 0.0081 15.8 14.3 1.2 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 EKX34341.1 - 0.011 14.6 14.9 0.011 14.5 14.9 1.2 1 0 0 1 1 1 0 Presenilin MDM10 PF12519.8 EKX34341.1 - 0.013 14.4 7.2 0.011 14.6 7.2 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF5308 PF17233.2 EKX34341.1 - 0.03 14.5 7.3 0.037 14.3 7.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Med15 PF09606.10 EKX34341.1 - 0.043 12.5 27.0 0.054 12.2 27.0 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Sin_N PF04801.13 EKX34341.1 - 0.053 12.7 21.4 0.054 12.7 21.4 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region SLC12 PF03522.15 EKX34341.1 - 0.054 12.5 12.0 0.058 12.4 12.0 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Peptidase_S64 PF08192.11 EKX34341.1 - 0.055 12.0 9.7 0.05 12.1 9.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 PAT1 PF09770.9 EKX34341.1 - 0.056 11.7 19.3 0.057 11.7 19.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Endostatin PF06482.11 EKX34341.1 - 0.062 12.8 12.7 0.089 12.2 12.7 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF4175 PF13779.6 EKX34341.1 - 0.067 11.1 31.1 0.072 11.0 31.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) EOS1 PF12326.8 EKX34341.1 - 0.26 11.2 6.7 0.53 10.2 6.7 1.5 1 0 0 1 1 1 0 N-glycosylation protein DUF4407 PF14362.6 EKX34341.1 - 0.27 10.5 15.6 0.29 10.5 15.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM222A PF15258.6 EKX34341.1 - 0.35 9.9 20.2 0.47 9.5 20.2 1.1 1 0 0 1 1 1 0 Protein family of FAM222A PepSY_TM PF03929.16 EKX34341.1 - 0.38 10.4 4.4 0.43 10.2 4.4 1.2 1 0 0 1 1 1 0 PepSY-associated TM region DUF2151 PF10221.9 EKX34341.1 - 0.42 9.1 11.2 0.49 8.9 11.2 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator DUF913 PF06025.12 EKX34341.1 - 0.43 9.5 10.9 0.6 9.0 10.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Plasmodium_Vir PF05795.11 EKX34341.1 - 0.49 9.8 9.7 0.6 9.5 9.7 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4637 PF15470.6 EKX34341.1 - 0.54 10.0 17.2 0.059 13.1 12.9 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4637) ABC2_membrane_2 PF12679.7 EKX34341.1 - 0.58 9.4 1.8 0.51 9.6 1.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein CPSF100_C PF13299.6 EKX34341.1 - 0.66 10.1 17.5 0.29 11.3 15.2 1.5 2 0 0 2 2 1 0 Cleavage and polyadenylation factor 2 C-terminal RMP PF14996.6 EKX34341.1 - 0.66 10.2 11.6 1.4 9.1 11.6 1.5 1 0 0 1 1 1 0 Retinal Maintenance Zip PF02535.22 EKX34341.1 - 0.77 8.9 7.3 0.77 8.9 7.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 EKX34341.1 - 0.77 8.0 19.3 0.93 7.7 19.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 EKX34341.1 - 0.78 8.5 13.2 1 8.1 13.2 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hid1 PF12722.7 EKX34341.1 - 0.87 7.6 14.2 1.1 7.4 14.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GREB1 PF15782.5 EKX34341.1 - 0.91 6.6 11.2 0.96 6.5 11.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RP-C_C PF11800.8 EKX34341.1 - 1 9.4 13.9 1.5 8.9 13.9 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Otopetrin PF03189.13 EKX34341.1 - 1.1 8.0 6.1 1.2 7.9 6.1 1.1 1 0 0 1 1 1 0 Otopetrin Mem_trans PF03547.18 EKX34341.1 - 2.1 6.7 5.0 2.1 6.7 5.0 1.1 1 0 0 1 1 1 0 Membrane transport protein TERB2 PF15101.6 EKX34341.1 - 2.3 8.2 22.8 3.9 7.5 22.8 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Ndc1_Nup PF09531.10 EKX34341.1 - 2.3 6.8 10.4 2.3 6.8 10.4 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PTPRCAP PF15713.5 EKX34341.1 - 2.6 8.3 28.8 0.78 10.0 25.9 1.6 2 0 0 2 2 1 0 Protein tyrosine phosphatase receptor type C-associated GOLD_2 PF13897.6 EKX34341.1 - 3.1 8.3 5.9 6.3 7.3 5.9 1.6 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Paramyxo_ncap PF00973.19 EKX34341.1 - 3.3 6.5 14.0 1.7 7.5 9.7 2.1 2 0 0 2 2 2 0 Paramyxovirus nucleocapsid protein CCDC53 PF10152.9 EKX34341.1 - 3.4 8.1 19.8 5.5 7.4 19.8 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Borrelia_P83 PF05262.11 EKX34341.1 - 3.4 6.1 18.3 3.7 5.9 18.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein RNA_pol_Rpc4 PF05132.14 EKX34341.1 - 3.9 7.9 20.7 0.6 10.5 16.6 1.7 2 0 0 2 2 2 0 RNA polymerase III RPC4 AP-5_subunit_s1 PF15001.6 EKX34341.1 - 4.4 7.3 19.4 3.4 7.6 17.9 1.5 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 RAG1_imp_bd PF12560.8 EKX34341.1 - 4.5 6.7 12.9 7.3 6.0 12.9 1.3 1 0 0 1 1 1 0 RAG1 importin binding Tim54 PF11711.8 EKX34341.1 - 4.6 5.9 20.7 0.93 8.2 17.6 1.4 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Cellulose_synt PF03552.14 EKX34341.1 - 5.1 5.4 5.1 5.1 5.4 5.1 1.2 1 0 0 1 1 1 0 Cellulose synthase eIF-3_zeta PF05091.12 EKX34341.1 - 6.3 5.6 22.3 9.6 5.0 22.3 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MPM1 PF17234.2 EKX34341.1 - 7.2 6.8 21.5 1.5 9.0 17.6 1.8 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 Membralin PF09746.9 EKX34341.1 - 7.4 5.5 10.2 10 5.1 10.2 1.2 1 0 0 1 1 1 0 Tumour-associated protein DUF2370 PF10176.9 EKX34341.1 - 7.6 6.1 8.1 12 5.5 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) UPF0560 PF10577.9 EKX34341.1 - 7.8 4.9 25.6 11 4.4 25.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 VIT1 PF01988.19 EKX34341.1 - 9.1 6.1 8.3 13 5.6 8.3 1.4 1 0 0 1 1 1 0 VIT family MCM_bind PF09739.9 EKX34341.1 - 9.2 4.6 16.9 12 4.1 16.9 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor FHIPEP PF00771.20 EKX34341.1 - 9.6 4.5 9.6 14 4.0 9.6 1.3 1 0 0 1 1 1 0 FHIPEP family MMU163 PF17119.5 EKX34341.1 - 9.9 5.2 10.1 4.8 6.3 8.2 1.4 2 0 0 2 2 1 0 Mitochondrial protein up-regulated during meiosis NAPRTase_C PF17956.1 EKX34342.1 - 1.9e-18 66.9 0.0 1.3e-17 64.2 0.0 1.9 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase_N PF17767.1 EKX34343.1 - 1.6e-42 144.8 0.2 1.9e-42 144.6 0.2 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain QRPTase_N PF02749.16 EKX34343.1 - 0.026 14.6 0.0 0.2 11.7 0.0 2.1 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain Adhes-Ig_like PF09085.10 EKX34344.1 - 0.014 15.5 0.2 0.036 14.2 0.2 1.7 1 0 0 1 1 1 0 Adhesion molecule, immunoglobulin-like Kelch_1 PF01344.25 EKX34345.1 - 1.3e-55 184.8 7.4 6.5e-13 48.1 0.2 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 EKX34345.1 - 2.6e-32 110.0 2.8 1.1e-06 28.7 0.0 7.1 4 2 3 7 7 7 5 Kelch motif Kelch_2 PF07646.15 EKX34345.1 - 4.1e-19 67.7 6.2 0.00022 21.1 0.0 6.7 7 0 0 7 7 7 4 Kelch motif Kelch_3 PF13415.6 EKX34345.1 - 4.3e-14 52.4 9.7 0.0001 22.5 0.0 6.4 8 0 0 8 8 8 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EKX34345.1 - 4.7e-10 39.2 2.7 0.088 12.8 0.0 5.6 4 1 1 5 5 5 3 Kelch motif WW PF00397.26 EKX34345.1 - 1.2e-07 31.6 0.8 2.7e-07 30.6 0.8 1.6 1 0 0 1 1 1 1 WW domain Kelch_4 PF13418.6 EKX34345.1 - 1.1e-06 28.5 12.0 0.054 13.5 0.1 5.7 7 1 1 8 8 8 3 Galactose oxidase, central domain Nucleoporin_FG PF13634.6 EKX34345.1 - 0.00061 20.6 46.3 0.0018 19.1 17.7 3.4 1 1 3 4 4 4 4 Nucleoporin FG repeat region DUF1668 PF07893.13 EKX34345.1 - 0.015 14.7 0.0 2.7 7.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1668) AAA_11 PF13086.6 EKX34347.1 - 0.00013 21.8 0.0 0.00013 21.8 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EKX34347.1 - 0.0027 18.2 2.8 0.004 17.6 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EKX34347.1 - 0.0064 16.1 2.1 0.0099 15.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EKX34347.1 - 0.019 14.7 0.0 0.019 14.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EKX34347.1 - 0.019 14.5 0.0 0.044 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 EKX34347.1 - 0.14 12.6 0.0 0.14 12.6 0.0 2.7 2 2 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EKX34347.1 - 0.35 11.1 0.0 0.35 11.1 0.0 3.0 2 1 0 2 2 2 0 AAA domain Ndc1_Nup PF09531.10 EKX34347.1 - 6.5 5.3 10.7 9.2 4.8 10.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Borrelia_P83 PF05262.11 EKX34348.1 - 0.2 10.1 34.0 0.23 9.9 34.0 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein AAA_15 PF13175.6 EKX34348.1 - 0.94 9.1 27.0 1.2 8.8 27.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Velvet PF11754.8 EKX34349.1 - 0.01 15.8 0.4 0.013 15.5 0.4 1.1 1 0 0 1 1 1 1 Velvet factor Dynactin_p62 PF05502.13 EKX34349.1 - 0.013 14.3 5.6 0.023 13.5 5.6 1.3 1 0 0 1 1 1 0 Dynactin p62 family Chalcone_3 PF16036.5 EKX34349.1 - 0.043 13.9 5.3 0.072 13.2 5.3 1.3 1 0 0 1 1 1 0 Chalcone isomerase-like OmpH PF03938.14 EKX34349.1 - 0.16 12.3 18.0 0.23 11.8 18.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) AIF_C PF14721.6 EKX34349.1 - 0.37 11.1 2.5 0.63 10.4 2.5 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Nbl1_Borealin_N PF10444.9 EKX34349.1 - 2.1 8.0 13.4 14 5.4 3.9 2.4 1 1 1 2 2 2 0 Nbl1 / Borealin N terminal CSG2 PF16965.5 EKX34349.1 - 2.7 6.9 4.5 4.7 6.1 4.5 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator Connexin PF00029.19 EKX34349.1 - 4.2 7.1 6.5 6.2 6.5 6.5 1.2 1 0 0 1 1 1 0 Connexin Fe-S_biosyn PF01521.20 EKX34352.1 - 4.2e-22 78.4 0.0 6e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis SMC_N PF02463.19 EKX34353.1 - 1.2 8.5 4.1 0.61 9.5 0.2 2.3 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain EF-hand_1 PF00036.32 EKX34355.1 - 2.2e-20 70.6 12.2 1.2e-07 30.8 1.5 4.7 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 EKX34355.1 - 5.6e-18 65.2 9.4 9.8e-09 35.5 0.3 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX34355.1 - 3.1e-17 60.9 10.9 9.8e-06 25.1 0.1 4.5 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EKX34355.1 - 3.2e-16 58.9 9.0 1.3e-06 28.2 0.2 4.1 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EKX34355.1 - 1e-13 50.1 17.4 3.2e-06 26.4 2.3 4.9 5 1 1 6 6 6 3 EF hand SPARC_Ca_bdg PF10591.9 EKX34355.1 - 0.00051 20.3 2.8 0.18 12.1 0.6 2.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EKX34355.1 - 0.0013 19.0 0.6 0.23 11.8 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 EKX34355.1 - 0.0034 17.3 9.3 0.06 13.3 0.3 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand T6PP_N PF18572.1 EKX34355.1 - 0.019 14.8 0.0 0.12 12.3 0.0 2.1 1 1 1 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Snapin_Pallidin PF14712.6 EKX34355.1 - 0.044 14.2 0.1 0.11 12.9 0.1 1.7 1 1 0 1 1 1 0 Snapin/Pallidin DUF2624 PF11116.8 EKX34355.1 - 0.088 13.7 0.2 0.41 11.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2624) EF-hand_like PF09279.11 EKX34355.1 - 0.088 13.3 1.6 9.1 6.8 0.0 2.3 1 1 1 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like Beta-TrCP_D PF12125.8 EKX34355.1 - 0.7 9.8 3.9 0.23 11.4 1.0 1.8 2 0 0 2 2 2 0 D domain of beta-TrCP Cupin_3 PF05899.12 EKX34356.1 - 1.6e-30 104.6 1.5 2e-30 104.3 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 EKX34356.1 - 2.5e-07 30.3 0.0 3.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Cupin domain EutQ PF06249.12 EKX34356.1 - 2.9e-06 27.1 0.0 3.5e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_6 PF12852.7 EKX34356.1 - 0.0013 18.4 0.0 0.0014 18.3 0.0 1.1 1 0 0 1 1 1 1 Cupin DUF5001 PF16392.5 EKX34356.1 - 0.024 14.5 0.0 0.031 14.2 0.0 1.1 1 0 0 1 1 1 0 Ig-like domain AraC_binding PF02311.19 EKX34356.1 - 0.11 12.4 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 AraC-like ligand binding domain Pkinase PF00069.25 EKX34358.1 - 5.9e-42 143.9 0.0 1.3e-41 142.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX34358.1 - 5.5e-28 98.0 0.0 1.3e-26 93.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX34358.1 - 2.4e-08 33.6 1.5 9e-08 31.8 0.3 2.3 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EKX34358.1 - 0.021 14.2 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_membrane PF00664.23 EKX34359.1 - 2.2e-35 122.7 8.0 3.3e-35 122.1 8.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EKX34359.1 - 6.2e-33 114.2 0.1 2e-32 112.6 0.0 2.0 2 0 0 2 2 2 1 ABC transporter ABC_ATPase PF09818.9 EKX34359.1 - 0.00085 18.2 1.2 0.48 9.2 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class SMC_N PF02463.19 EKX34359.1 - 0.001 18.5 0.0 0.0043 16.5 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_membrane_2 PF06472.15 EKX34359.1 - 0.0056 16.1 2.2 0.01 15.3 2.2 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 AAA_22 PF13401.6 EKX34359.1 - 0.021 15.1 0.1 0.091 13.0 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EKX34359.1 - 0.032 14.0 0.3 0.085 12.6 0.3 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 EKX34359.1 - 0.048 13.9 0.1 0.13 12.5 0.1 1.8 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit OATP PF03137.20 EKX34359.1 - 0.058 11.7 0.6 0.11 10.8 0.6 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Terminase_2 PF03592.16 EKX34359.1 - 0.15 12.5 1.0 1 9.8 0.2 2.3 2 0 0 2 2 2 0 Terminase small subunit DUF5526 PF17664.1 EKX34359.1 - 8.4 5.9 6.0 11 5.5 0.2 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5526) Tubulin PF00091.25 EKX34360.1 - 6e-68 228.9 0.0 1.2e-67 227.9 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EKX34360.1 - 8.6e-42 142.3 0.2 1.3e-41 141.7 0.2 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EKX34360.1 - 9.4e-05 22.7 0.0 0.00024 21.4 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EKX34360.1 - 0.0025 17.5 0.0 0.0044 16.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EKX34360.1 - 0.036 13.3 0.1 0.086 12.0 0.0 1.6 2 0 0 2 2 2 0 Tubulin like Het-C PF07217.11 EKX34360.1 - 0.11 11.0 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Pirin PF02678.16 EKX34361.1 - 2e-08 34.2 0.1 3.5e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 Pirin CLASP_N PF12348.8 EKX34362.1 - 7.8e-22 77.9 0.6 1.4e-21 77.2 0.6 1.4 1 0 0 1 1 1 1 CLASP N terminal DUF728 PF05304.12 EKX34362.1 - 0.24 11.2 3.8 0.19 11.6 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF728) Flavodoxin_1 PF00258.25 EKX34363.1 - 1.9e-28 99.5 0.0 2.1e-28 99.4 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin UQ_con PF00179.26 EKX34365.1 - 8.5e-50 168.0 0.1 9.7e-50 167.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EKX34365.1 - 8e-05 22.4 0.0 0.0001 22.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EKX34365.1 - 0.0022 17.9 0.1 0.0046 16.8 0.1 1.6 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 EKX34365.1 - 0.057 13.7 0.1 0.068 13.5 0.1 1.4 1 1 0 1 1 1 0 RWD domain Methyltransf_23 PF13489.6 EKX34366.1 - 2.2e-14 53.6 0.1 1.1e-13 51.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX34366.1 - 8.5e-12 45.1 0.0 1.6e-11 44.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX34366.1 - 7.1e-10 39.5 0.1 9.5e-09 35.9 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX34366.1 - 1.5e-09 38.4 0.1 4.7e-08 33.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX34366.1 - 2.5e-05 24.9 0.0 0.00057 20.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EKX34366.1 - 0.00042 19.8 0.0 0.00059 19.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 EKX34366.1 - 0.0012 18.9 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EKX34366.1 - 0.0012 18.4 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Peptidase_M8 PF01457.16 EKX34366.1 - 0.0025 16.6 0.0 0.0032 16.2 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin Pox_MCEL PF03291.16 EKX34366.1 - 0.015 14.5 0.0 0.28 10.3 0.0 2.1 2 0 0 2 2 2 0 mRNA capping enzyme Methyltransf_9 PF08003.11 EKX34366.1 - 0.02 13.8 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) CMAS PF02353.20 EKX34366.1 - 0.037 13.3 0.0 0.66 9.2 0.0 2.2 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase AdoMet_MTase PF07757.13 EKX34366.1 - 0.048 14.0 0.0 0.071 13.4 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase TehB PF03848.14 EKX34366.1 - 0.049 13.0 0.1 0.093 12.1 0.0 1.5 2 0 0 2 2 2 0 Tellurite resistance protein TehB MetW PF07021.12 EKX34366.1 - 0.055 13.1 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PCMT PF01135.19 EKX34366.1 - 0.18 11.5 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PRR22 PF15776.5 EKX34367.1 - 1.6 8.0 5.9 1.4 8.2 4.8 1.4 1 1 0 1 1 1 0 Proline-rich protein family 22 MutS_V PF00488.21 EKX34368.1 - 8.9e-65 218.3 0.0 1.7e-64 217.4 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EKX34368.1 - 3.8e-24 86.0 0.6 8.2e-24 84.9 0.6 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 EKX34368.1 - 3.6e-14 52.9 0.0 1.5e-13 50.9 0.0 2.1 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 EKX34368.1 - 2.2e-09 37.7 0.0 6.6e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 MutS domain II HTH_36 PF13730.6 EKX34368.1 - 0.037 14.0 0.0 0.25 11.3 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain LRR_4 PF12799.7 EKX34369.1 - 2.1e-20 72.4 31.3 5.9e-05 23.4 3.6 6.5 5 2 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX34369.1 - 9.7e-13 47.7 30.4 0.0028 17.4 0.9 5.3 4 2 1 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 EKX34369.1 - 1.5e-08 34.4 7.4 0.0024 17.4 2.4 3.1 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 EKX34369.1 - 0.0022 17.9 19.7 1.1 9.5 0.0 7.7 9 0 0 9 9 9 3 Leucine Rich repeat LRR_1 PF00560.33 EKX34369.1 - 5.3 8.0 25.7 1.7 9.5 0.2 7.3 6 4 1 7 7 7 0 Leucine Rich Repeat HAD_2 PF13419.6 EKX34370.1 - 2.8e-17 63.4 0.0 3.5e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EKX34370.1 - 1.5e-08 35.2 0.0 3.6e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EKX34370.1 - 0.00065 19.7 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EKX34370.1 - 0.0007 20.0 0.0 0.0009 19.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Peptidase_M13 PF01431.21 EKX34371.1 - 7.5e-54 182.4 0.0 1.4e-53 181.6 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13_N PF05649.13 EKX34371.1 - 8.8e-18 65.1 0.3 1.8e-17 64.1 0.3 1.5 1 0 0 1 1 1 1 Peptidase family M13 Fer2 PF00111.27 EKX34372.1 - 2.2e-07 30.7 0.4 3.6e-07 30.0 0.0 1.6 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 EKX34372.1 - 0.0023 17.9 0.2 0.0041 17.1 0.2 1.7 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_4 PF13510.6 EKX34372.1 - 0.1 12.6 0.7 0.68 10.0 0.1 2.3 2 1 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Kinesin PF00225.23 EKX34373.1 - 2.6e-105 352.1 0.2 2.8e-105 351.9 0.2 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX34373.1 - 1.5e-42 145.0 0.0 2.6e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding CBM_20 PF00686.19 EKX34374.1 - 1.2e-11 44.4 0.1 1.4e-11 44.2 0.1 1.1 1 0 0 1 1 1 1 Starch binding domain GTP_EFTU PF00009.27 EKX34376.1 - 9.3e-23 80.8 0.3 1.6e-22 80.0 0.3 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EKX34376.1 - 1.1e-07 32.1 0.0 3.8e-07 30.4 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EKX34376.1 - 2.4e-05 24.6 0.5 0.00033 21.0 0.1 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EKX34376.1 - 0.004 17.2 0.2 0.011 15.9 0.2 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EKX34376.1 - 0.1 12.3 1.0 41 3.9 0.0 3.8 2 1 1 4 4 4 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EKX34376.1 - 0.21 11.0 1.3 7.8 5.9 0.0 2.7 2 1 1 3 3 3 0 Signal recognition particle receptor beta subunit zf-CDGSH PF09360.10 EKX34377.1 - 9.3e-16 57.8 1.1 4.5e-07 30.0 0.1 2.1 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type Toxin_14 PF07829.11 EKX34377.1 - 2.7 8.0 10.0 0.81 9.7 2.3 2.3 2 0 0 2 2 2 0 Alpha-A conotoxin PIVA-like protein DUF4215 PF13948.6 EKX34378.1 - 2.9e-06 27.6 2.8 2.9e-06 27.6 2.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4215) ZU5 PF00791.20 EKX34378.1 - 5.6e-06 26.6 0.0 1.5e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 ZU5 domain CTD PF12815.7 EKX34378.1 - 0.066 13.8 44.5 0.051 14.1 5.2 4.6 2 1 2 4 4 4 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Hamartin PF04388.12 EKX34378.1 - 4.1 5.9 37.0 7.6 5.1 37.0 1.4 1 0 0 1 1 1 0 Hamartin protein EF-hand_7 PF13499.6 EKX34380.1 - 1.5e-08 34.9 0.7 0.00031 21.1 0.1 1.7 1 1 1 2 2 2 2 EF-hand domain pair Ank_2 PF12796.7 EKX34380.1 - 3.3e-07 30.8 0.2 7.5e-07 29.7 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX34380.1 - 6.8e-07 29.5 0.0 2.6e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) EF-hand_6 PF13405.6 EKX34380.1 - 1e-05 25.1 0.0 3e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain Ank_4 PF13637.6 EKX34380.1 - 0.00014 22.3 0.0 0.0026 18.3 0.0 2.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) EF-hand_1 PF00036.32 EKX34380.1 - 0.00017 20.9 0.1 0.00046 19.5 0.1 1.8 1 0 0 1 1 1 1 EF hand Ank PF00023.30 EKX34380.1 - 0.00033 21.0 0.2 0.22 12.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EKX34380.1 - 0.0008 19.7 0.0 3.6 8.5 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat PH PF00169.29 EKX34380.1 - 0.0019 18.7 1.3 0.011 16.3 1.3 2.1 1 1 0 1 1 1 1 PH domain EF-hand_5 PF13202.6 EKX34380.1 - 0.025 14.1 0.0 0.065 12.8 0.0 1.7 1 0 0 1 1 1 0 EF hand SPARC_Ca_bdg PF10591.9 EKX34380.1 - 0.22 11.8 0.2 0.22 11.8 0.2 2.1 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Pept_tRNA_hydro PF01195.19 EKX34381.1 - 7.7e-42 143.1 0.0 8.4e-42 143.0 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Shugoshin_N PF07558.11 EKX34383.1 - 0.012 15.5 0.1 0.028 14.3 0.1 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region HALZ PF02183.18 EKX34383.1 - 0.031 14.5 2.3 0.54 10.5 0.9 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Atg14 PF10186.9 EKX34383.1 - 1 8.4 4.3 3.2 6.7 1.2 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 SHIPPO-rpt PF07004.12 EKX34384.1 - 1.1e-06 29.2 20.3 0.003 18.4 0.1 5.5 5 0 0 5 5 5 4 Sperm-tail PG-rich repeat Rep_1B PF17873.1 EKX34384.1 - 0.11 12.4 0.4 0.71 9.8 0.0 2.5 3 0 0 3 3 3 0 Replicase polyprotein 1ab Glyco_transf_41 PF13844.6 EKX34385.1 - 8.6e-57 192.6 6.7 5.1e-29 101.0 1.4 2.9 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_2 PF07719.17 EKX34385.1 - 4.2e-09 35.8 1.8 0.3 11.3 0.0 5.0 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX34385.1 - 6.3e-08 32.1 0.0 0.011 15.5 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX34385.1 - 1.5e-06 28.4 0.2 0.0012 19.0 0.0 3.5 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX34385.1 - 2.3e-06 27.2 0.0 0.03 14.4 0.0 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX34385.1 - 5.5e-06 26.8 1.7 0.0095 16.4 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 EKX34385.1 - 8.2e-06 26.0 0.6 0.53 11.1 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX34385.1 - 3e-05 23.9 0.0 0.75 10.2 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX34385.1 - 0.00023 20.8 0.0 0.12 12.0 0.0 3.1 3 0 0 3 3 3 1 TPR repeat TPR_10 PF13374.6 EKX34385.1 - 0.00054 19.7 0.0 0.71 9.8 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX34385.1 - 0.0012 19.5 3.6 3.5 8.7 0.0 5.1 3 1 2 5 5 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX34385.1 - 0.0036 17.5 0.0 1.2 9.4 0.0 2.8 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 EKX34385.1 - 0.0074 16.7 0.2 0.31 11.5 0.0 2.5 1 1 1 2 2 2 1 Bacterial transcriptional activator domain DUF3856 PF12968.7 EKX34385.1 - 0.098 12.7 0.0 22 5.1 0.0 2.6 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) ABC1 PF03109.16 EKX34386.1 - 1.7e-23 83.0 0.0 2.8e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 EKX34386.1 - 0.0002 20.8 0.0 0.015 14.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EKX34386.1 - 0.00052 19.4 0.0 0.34 10.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EKX34386.1 - 0.003 17.5 0.1 0.008 16.1 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EKX34386.1 - 0.006 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family ABC_tran PF00005.27 EKX34388.1 - 4e-48 163.4 0.0 1.1e-23 84.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EKX34388.1 - 1.2e-20 73.3 2.5 1.2e-20 73.3 2.5 3.5 4 0 0 4 4 2 1 ABC transporter AAA_21 PF13304.6 EKX34388.1 - 2.5e-17 63.7 2.5 0.0002 21.3 0.0 4.3 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EKX34388.1 - 1.9e-09 37.1 0.1 0.0026 17.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 EKX34388.1 - 3e-09 36.6 0.0 0.018 14.5 0.1 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EKX34388.1 - 3.1e-09 37.0 8.5 0.0058 16.4 0.0 4.3 3 2 0 4 4 4 3 AAA ATPase domain AAA_23 PF13476.6 EKX34388.1 - 1.3e-06 29.1 10.4 0.03 14.8 0.1 4.2 4 0 0 4 4 3 2 AAA domain RsgA_GTPase PF03193.16 EKX34388.1 - 8.5e-06 25.8 0.0 0.012 15.5 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 EKX34388.1 - 2e-05 25.1 0.0 0.42 11.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EKX34388.1 - 5.5e-05 23.4 0.0 0.52 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_27 PF13514.6 EKX34388.1 - 5.7e-05 22.8 0.0 0.095 12.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 EKX34388.1 - 7.2e-05 22.8 0.0 0.49 10.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 EKX34388.1 - 8.3e-05 22.6 0.2 0.18 11.9 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 EKX34388.1 - 8.5e-05 22.9 0.0 0.39 10.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 EKX34388.1 - 0.00013 22.4 0.0 0.051 14.0 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX34388.1 - 0.00019 21.8 0.0 0.093 13.1 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 EKX34388.1 - 0.00019 21.2 0.0 0.4 10.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EKX34388.1 - 0.00025 21.3 0.1 0.36 11.1 0.1 2.9 2 2 0 2 2 2 1 AAA domain DUF2813 PF11398.8 EKX34388.1 - 0.0003 20.2 0.0 0.063 12.5 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2813) NACHT PF05729.12 EKX34388.1 - 0.00043 20.2 0.1 0.76 9.7 0.0 2.7 3 0 0 3 3 2 2 NACHT domain RNA_helicase PF00910.22 EKX34388.1 - 0.0008 19.8 0.7 3.3 8.1 0.0 3.4 3 0 0 3 3 3 1 RNA helicase Dynamin_N PF00350.23 EKX34388.1 - 0.00089 19.4 4.5 0.27 11.3 0.0 3.9 3 1 1 4 4 4 1 Dynamin family G-alpha PF00503.20 EKX34388.1 - 0.0011 18.3 0.0 0.82 8.8 0.0 2.7 2 1 1 3 3 3 1 G-protein alpha subunit TsaE PF02367.17 EKX34388.1 - 0.0042 17.1 1.3 2.3 8.3 0.0 3.3 2 1 1 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 EKX34388.1 - 0.0043 16.6 0.0 5 6.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain UPF0565 PF10561.9 EKX34388.1 - 0.011 15.0 2.6 0.62 9.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 AAA_7 PF12775.7 EKX34388.1 - 0.021 14.3 0.0 5.7 6.4 0.0 2.7 3 0 0 3 3 3 0 P-loop containing dynein motor region DUF815 PF05673.13 EKX34388.1 - 0.027 13.6 0.2 1.6 7.8 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF815) MukB PF04310.12 EKX34388.1 - 0.028 14.2 0.1 9.8 5.9 0.0 2.9 3 0 0 3 3 3 0 MukB N-terminal T2SSE PF00437.20 EKX34388.1 - 0.033 13.2 0.0 3.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein SbcCD_C PF13558.6 EKX34388.1 - 0.034 14.4 0.1 1.4 9.2 0.0 3.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATP_bind_1 PF03029.17 EKX34388.1 - 0.042 13.6 0.1 8.6 6.1 0.0 2.8 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein Roc PF08477.13 EKX34388.1 - 0.051 13.8 0.0 5 7.4 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 EKX34388.1 - 0.056 12.4 0.0 4.5 6.2 0.0 2.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AFG1_ATPase PF03969.16 EKX34388.1 - 0.063 12.2 0.0 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 AFG1-like ATPase NB-ARC PF00931.22 EKX34388.1 - 0.063 12.5 0.0 1.1 8.4 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Pox_A32 PF04665.12 EKX34388.1 - 0.076 12.5 0.2 8 5.8 0.0 2.8 3 0 0 3 3 3 0 Poxvirus A32 protein AAA_5 PF07728.14 EKX34388.1 - 0.081 12.9 0.1 16 5.5 0.1 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 EKX34388.1 - 0.1 12.6 3.8 4.6 7.3 0.0 3.3 2 1 1 3 3 3 0 Helicase HerA, central domain cobW PF02492.19 EKX34388.1 - 0.11 12.1 0.4 14 5.2 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 EKX34388.1 - 0.12 12.1 0.0 8.4 6.1 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Vfa1 PF08432.10 EKX34388.1 - 7.7 6.8 10.3 9.4 6.5 4.9 2.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 RWP-RK PF02042.15 EKX34389.1 - 3.9e-23 81.1 0.2 4.3e-23 81.0 0.2 1.0 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX34391.1 - 2.6e-21 75.3 0.2 2.6e-21 75.3 0.2 1.8 2 0 0 2 2 2 1 RWP-RK domain DnaJ_CXXCXGXG PF00684.19 EKX34392.1 - 0.0038 17.6 60.8 0.011 16.1 27.6 5.1 1 1 5 6 6 6 4 DnaJ central domain DUF2188 PF09954.9 EKX34392.1 - 0.055 13.6 1.8 80 3.5 0.0 4.1 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2188) PdxJ PF03740.13 EKX34392.1 - 0.091 11.9 0.1 7.8 5.5 0.0 2.4 1 1 1 2 2 2 0 Pyridoxal phosphate biosynthesis protein PdxJ Phage_int_SAM_2 PF12834.7 EKX34392.1 - 0.22 12.3 5.7 23 5.8 0.1 4.5 1 1 4 6 6 6 0 Phage integrase, N-terminal EF-hand_1 PF00036.32 EKX34393.1 - 1.9e-07 30.1 3.3 0.002 17.5 0.0 3.4 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 EKX34393.1 - 3.3e-07 30.7 0.0 1.5e-06 28.6 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX34393.1 - 1.1e-06 28.1 0.1 0.052 13.5 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 EKX34393.1 - 0.0038 17.0 1.5 0.33 10.8 0.0 3.1 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX34393.1 - 0.0074 15.7 0.1 0.2 11.2 0.0 2.8 3 0 0 3 3 3 1 EF hand Myosin_N PF02736.19 EKX34393.1 - 0.1 12.5 0.9 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Ifi-6-16 PF06140.13 EKX34394.1 - 7.6e-15 54.6 37.8 7.6e-15 54.6 37.8 2.1 2 1 1 3 3 3 1 Interferon-induced 6-16 family FSA_C PF10479.9 EKX34394.1 - 1.2 7.2 6.1 1.4 6.9 6.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus AKAP7_NLS PF10469.9 EKX34396.1 - 2.4e-24 86.4 0.0 3.6e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain LigT_PEase PF02834.16 EKX34396.1 - 4.8e-05 23.5 0.0 0.0023 18.1 0.0 3.0 3 0 0 3 3 3 1 LigT like Phosphoesterase Ifi-6-16 PF06140.13 EKX34397.1 - 2.5e-14 52.9 40.0 2.5e-14 52.9 40.0 2.3 2 1 1 3 3 3 1 Interferon-induced 6-16 family MTD PF01993.18 EKX34399.1 - 0.027 13.8 0.0 0.03 13.6 0.0 1.0 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase Focal_AT PF03623.13 EKX34399.1 - 0.056 13.4 0.0 0.067 13.2 0.0 1.1 1 0 0 1 1 1 0 Focal adhesion targeting region AAA_13 PF13166.6 EKX34400.1 - 0.005 15.6 9.4 0.0068 15.1 9.4 1.0 1 0 0 1 1 1 1 AAA domain BST2 PF16716.5 EKX34400.1 - 0.014 15.9 15.0 0.39 11.3 4.3 2.6 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 DUF724 PF05266.14 EKX34400.1 - 0.022 14.6 12.9 0.14 12.0 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Wtap PF17098.5 EKX34400.1 - 0.048 13.6 14.6 0.067 13.1 12.9 2.2 2 1 0 2 2 1 0 WTAP/Mum2p family DUF1664 PF07889.12 EKX34400.1 - 0.052 13.6 11.0 0.16 12.0 2.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.15 EKX34400.1 - 0.064 13.0 13.1 0.12 12.2 0.8 2.9 2 2 0 2 2 2 0 Septum formation initiator Med21 PF11221.8 EKX34400.1 - 0.068 13.4 1.0 0.068 13.4 1.0 3.4 2 1 1 3 3 3 0 Subunit 21 of Mediator complex Tropomyosin PF00261.20 EKX34400.1 - 0.084 12.2 19.1 1.1 8.6 3.5 2.1 1 1 1 2 2 2 0 Tropomyosin Enkurin PF13864.6 EKX34400.1 - 0.12 12.8 8.2 0.082 13.4 5.7 1.9 1 1 0 2 2 1 0 Calmodulin-binding APG6_N PF17675.1 EKX34400.1 - 0.13 12.8 22.7 37 4.8 22.7 2.3 1 1 0 1 1 1 0 Apg6 coiled-coil region BRE1 PF08647.11 EKX34400.1 - 0.15 12.1 13.7 0.26 11.4 1.4 2.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase FPP PF05911.11 EKX34400.1 - 0.17 10.0 17.3 0.36 9.0 17.3 1.4 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil MscS_porin PF12795.7 EKX34400.1 - 0.18 11.4 19.9 0.28 10.7 19.9 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain UPF0242 PF06785.11 EKX34400.1 - 0.28 11.3 11.6 0.43 10.6 11.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 EKX34400.1 - 0.32 11.4 7.2 1.4 9.3 0.1 3.2 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Fez1 PF06818.15 EKX34400.1 - 0.47 10.9 16.2 0.92 9.9 16.2 1.5 1 1 0 1 1 1 0 Fez1 Exonuc_VII_L PF02601.15 EKX34400.1 - 0.5 9.9 11.3 0.74 9.3 11.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 EKX34400.1 - 0.6 9.4 10.8 0.99 8.7 10.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cnn_1N PF07989.11 EKX34400.1 - 0.62 10.3 11.7 4.7 7.4 1.7 2.7 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Syntaxin-6_N PF09177.11 EKX34400.1 - 0.63 10.6 13.2 0.39 11.3 7.8 2.5 2 1 1 3 3 2 0 Syntaxin 6, N-terminal NPV_P10 PF05531.12 EKX34400.1 - 0.63 10.5 6.1 2 8.9 1.7 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ZapB PF06005.12 EKX34400.1 - 0.73 10.3 16.6 1.8 9.1 1.3 3.1 2 1 1 3 3 3 0 Cell division protein ZapB CorA PF01544.18 EKX34400.1 - 0.9 8.8 8.8 1.3 8.3 8.8 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein FUSC PF04632.12 EKX34400.1 - 0.93 7.9 4.3 1.5 7.3 4.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family CP12 PF02672.15 EKX34400.1 - 0.96 10.3 5.0 4 8.3 0.8 2.4 2 0 0 2 2 2 0 CP12 domain AcylCoA_dehyd_C PF12186.8 EKX34400.1 - 1.1 9.4 3.8 6.4 6.9 0.4 2.3 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal Lebercilin PF15619.6 EKX34400.1 - 1.2 8.8 19.9 8 6.1 19.5 2.7 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Fib_alpha PF08702.10 EKX34400.1 - 1.3 9.2 11.6 1.1 9.4 1.3 2.7 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Bcr-Abl_Oligo PF09036.10 EKX34400.1 - 1.5 8.9 3.9 5.5 7.1 0.7 2.6 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Mod_r PF07200.13 EKX34400.1 - 1.8 8.7 17.8 3.9 7.6 8.2 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein MPS2 PF17060.5 EKX34400.1 - 1.9 7.6 8.0 2.9 7.1 7.2 1.4 1 1 0 1 1 1 0 Monopolar spindle protein 2 FliJ PF02050.16 EKX34400.1 - 2 8.7 15.1 1.2 9.3 5.5 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein SlyX PF04102.12 EKX34400.1 - 2.1 9.0 13.1 3 8.5 4.6 3.0 2 2 0 2 2 2 0 SlyX LPP PF04728.13 EKX34400.1 - 2.2 8.7 8.7 36 4.8 1.0 3.4 2 1 1 3 3 3 0 Lipoprotein leucine-zipper T3SSipB PF16535.5 EKX34400.1 - 2.3 8.7 13.4 0.72 10.3 1.4 2.2 1 1 0 2 2 2 0 Type III cell invasion protein SipB Atg14 PF10186.9 EKX34400.1 - 2.3 7.2 16.2 7.1 5.6 15.1 1.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 PEP-utilisers_N PF05524.13 EKX34400.1 - 3 8.1 8.3 0.82 9.9 2.6 2.2 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal PKcGMP_CC PF16808.5 EKX34400.1 - 3.2 7.7 10.4 0.57 10.1 0.2 3.7 4 0 0 4 4 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF948 PF06103.11 EKX34400.1 - 3.2 8.1 5.1 9.7 6.5 0.4 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Allexi_40kDa PF05549.11 EKX34400.1 - 3.4 7.1 7.4 3.8 7.0 5.9 1.8 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF1993 PF09351.10 EKX34400.1 - 3.4 7.8 6.8 2.9 8.0 1.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) CENP-F_leu_zip PF10473.9 EKX34400.1 - 3.5 7.7 18.6 3.5 7.7 7.2 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_CLD_2 PF14197.6 EKX34400.1 - 3.8 7.7 16.2 2.6 8.2 11.6 2.6 2 1 0 2 2 1 0 Centrosome localisation domain of PPC89 TMF_TATA_bd PF12325.8 EKX34400.1 - 4.4 7.5 17.9 1.7 8.9 3.0 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding OmpH PF03938.14 EKX34400.1 - 4.5 7.6 17.4 9.4 6.6 3.5 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) PRKG1_interact PF15898.5 EKX34400.1 - 4.6 8.2 18.2 4 8.4 10.4 3.0 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF641 PF04859.12 EKX34400.1 - 4.7 7.6 12.3 2.4 8.5 2.8 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) CC2-LZ PF16516.5 EKX34400.1 - 4.8 7.6 15.6 1.5 9.2 11.2 2.4 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF4472 PF14739.6 EKX34400.1 - 5.5 7.8 15.5 3.1 8.6 7.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) ABC_tran_CTD PF16326.5 EKX34400.1 - 7.4 6.9 15.1 9.8 6.5 6.6 2.8 1 1 1 2 2 2 0 ABC transporter C-terminal domain DUF3450 PF11932.8 EKX34400.1 - 8.3 5.6 17.2 1 8.6 3.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) KduI PF04962.12 EKX34401.1 - 0.061 12.6 0.2 0.11 11.8 0.2 1.4 1 1 0 1 1 1 0 KduI/IolB family Pkinase PF00069.25 EKX34402.1 - 1.2e-60 205.2 0.0 2e-60 204.4 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX34402.1 - 2.2e-31 109.1 0.3 9.1e-27 94.0 0.1 2.0 1 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EKX34402.1 - 1.3e-07 31.2 0.2 5.1e-06 26.0 0.0 2.7 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EKX34402.1 - 7.8e-06 24.9 0.0 1.2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX34402.1 - 7.8e-06 26.0 0.1 0.00023 21.2 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EKX34402.1 - 0.00013 21.6 1.1 0.00059 19.5 0.0 1.9 1 1 0 2 2 2 1 RIO1 family FTA2 PF13095.6 EKX34402.1 - 0.00065 19.4 0.5 0.5 9.9 0.0 2.1 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EKX34402.1 - 0.0024 16.9 0.1 0.003 16.5 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EKX34402.1 - 0.021 14.2 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EKX34402.1 - 0.05 12.7 0.2 0.075 12.1 0.2 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.9 EKX34402.1 - 0.093 12.2 0.1 0.17 11.4 0.1 1.3 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.11 EKX34402.1 - 0.095 11.7 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Sulfotransfer_2 PF03567.14 EKX34404.1 - 2e-05 24.6 0.5 2e-05 24.6 0.5 2.2 2 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_3 PF13469.6 EKX34404.1 - 0.02 15.3 1.3 0.048 14.0 1.3 1.8 1 1 0 1 1 1 0 Sulfotransferase family Glycos_transf_2 PF00535.26 EKX34405.1 - 0.00072 19.4 0.0 0.0031 17.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 OTU PF02338.19 EKX34406.1 - 1.6e-20 73.9 0.4 3.9e-20 72.6 0.4 1.7 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EKX34406.1 - 2.8e-10 40.1 0.1 2e-05 24.2 0.0 2.5 2 0 0 2 2 2 2 Peptidase C65 Otubain CDC27 PF09507.10 EKX34406.1 - 0.65 9.3 22.7 0.92 8.8 22.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RP-C_C PF11800.8 EKX34406.1 - 0.79 9.8 5.4 1.3 9.1 5.4 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region TMEM252 PF15664.5 EKX34406.1 - 1.3 8.8 4.5 2.3 7.9 4.5 1.4 1 0 0 1 1 1 0 Transmembrane protein 252 family Nop53 PF07767.11 EKX34406.1 - 1.5 8.1 22.4 2.5 7.4 22.4 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF2052 PF09747.9 EKX34406.1 - 2.3 8.3 17.3 4.2 7.4 17.3 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CDC45 PF02724.14 EKX34406.1 - 2.7 6.2 13.5 3.3 5.9 13.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 EKX34406.1 - 4.2 6.0 9.7 4.8 5.8 9.7 1.1 1 0 0 1 1 1 0 Presenilin Suf PF05843.14 EKX34406.1 - 5.6 6.9 8.3 7.9 6.4 8.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PGA2 PF07543.12 EKX34406.1 - 6.9 6.6 20.9 4.2 7.3 17.1 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 DUF3381 PF11861.8 EKX34406.1 - 7.3 6.4 17.8 13 5.6 17.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DBC1 PF14443.6 EKX34407.1 - 2e-29 102.1 0.0 3.3e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 DBC1 RIFIN PF02009.16 EKX34407.1 - 0.16 11.8 0.7 0.33 10.8 0.7 1.4 1 0 0 1 1 1 0 Rifin Macoilin PF09726.9 EKX34407.1 - 1.2 7.6 5.6 2.5 6.5 5.6 1.5 1 0 0 1 1 1 0 Macoilin family BAF1_ABF1 PF04684.13 EKX34407.1 - 6.6 5.7 8.1 6.7 5.6 4.3 2.0 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor DUF4407 PF14362.6 EKX34408.1 - 0.23 10.7 2.6 0.27 10.5 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Bindin PF02084.15 EKX34409.1 - 1.8 8.8 9.0 3 8.0 9.0 1.3 1 0 0 1 1 1 0 Bindin DUF2627 PF11118.8 EKX34411.1 - 0.0013 19.3 0.0 0.0041 17.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2627) HTH_Tnp_Tc5 PF03221.16 EKX34412.1 - 2.5e-07 30.6 0.0 4.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain PB1 PF00564.24 EKX34412.1 - 2.7e-06 27.2 0.0 7e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 PB1 domain CENP-B_N PF04218.13 EKX34412.1 - 7.3e-05 22.3 0.4 0.00028 20.5 0.1 2.0 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_3 PF01381.22 EKX34412.1 - 0.0059 16.6 0.0 0.018 15.1 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix HTH_Crp_2 PF13545.6 EKX34412.1 - 0.07 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain MRP-L20 PF12824.7 EKX34412.1 - 0.075 13.2 0.7 0.14 12.3 0.1 1.6 2 0 0 2 2 2 0 Mitochondrial ribosomal protein subunit L20 VPS13_C PF16909.5 EKX34412.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Sigma70_r4 PF04545.16 EKX34412.1 - 0.14 11.7 0.0 0.35 10.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 DUF126 PF01989.16 EKX34413.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Aconitase X swivel domain Peptidase_C48 PF02902.19 EKX34413.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain DUF1806 PF08830.10 EKX34416.1 - 1.8e-06 27.8 1.1 85 3.1 0.0 9.2 6 2 4 11 11 11 2 Protein of unknown function (DUF1806) ZU5 PF00791.20 EKX34417.1 - 3.9e-05 23.9 0.0 8.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 ZU5 domain DUF2627 PF11118.8 EKX34417.1 - 0.0069 16.9 0.0 0.022 15.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2627) Big_3 PF07523.12 EKX34417.1 - 0.062 13.6 0.3 0.14 12.5 0.3 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) HTH_Tnp_Tc5 PF03221.16 EKX34418.1 - 2e-07 30.9 0.0 3.8e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain PB1 PF00564.24 EKX34418.1 - 2.8e-06 27.2 0.0 7.1e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 PB1 domain CENP-B_N PF04218.13 EKX34418.1 - 7.6e-05 22.3 0.4 0.00029 20.4 0.1 2.0 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_3 PF01381.22 EKX34418.1 - 0.0074 16.3 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix HTH_Crp_2 PF13545.6 EKX34418.1 - 0.071 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain VPS13_C PF16909.5 EKX34418.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Sigma70_r4 PF04545.16 EKX34418.1 - 0.15 11.6 0.0 0.36 10.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 REJ PF02010.15 EKX34419.1 - 2.2e-07 30.0 7.9 0.0025 16.7 0.2 3.7 1 1 2 4 4 4 3 REJ domain HTH_Tnp_Tc5 PF03221.16 EKX34420.1 - 1e-09 38.3 0.0 2e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 EKX34420.1 - 5.7e-07 29.1 0.6 2.7e-06 26.9 0.2 2.2 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain PB1 PF00564.24 EKX34420.1 - 2e-06 27.6 0.0 4.6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 PB1 domain HTH_Crp_2 PF13545.6 EKX34420.1 - 0.00043 20.2 0.0 0.00099 19.0 0.0 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_3 PF01381.22 EKX34420.1 - 0.00085 19.3 0.0 0.0029 17.6 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix Sigma70_r4 PF04545.16 EKX34420.1 - 0.00095 18.6 0.0 0.0049 16.4 0.0 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_28 PF13518.6 EKX34420.1 - 0.0089 16.1 0.0 0.51 10.5 0.0 2.4 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 EKX34420.1 - 0.012 15.4 0.0 0.049 13.4 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_29 PF13551.6 EKX34420.1 - 0.014 15.4 0.0 0.14 12.2 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn helix MarR_2 PF12802.7 EKX34420.1 - 0.026 14.4 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 MarR family PuR_N PF09182.10 EKX34420.1 - 0.029 14.3 0.1 0.23 11.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal DUF4817 PF16087.5 EKX34420.1 - 0.042 13.7 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) HTH_Tnp_4 PF13613.6 EKX34420.1 - 0.043 13.5 0.0 0.092 12.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MarR PF01047.22 EKX34420.1 - 0.058 13.3 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 MarR family Cro PF09048.10 EKX34420.1 - 0.085 12.9 0.1 0.47 10.5 0.0 2.2 2 0 0 2 2 2 0 Cro HTH_24 PF13412.6 EKX34420.1 - 0.1 12.2 0.0 0.28 10.8 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding SL4P PF17618.2 EKX34420.1 - 0.16 12.0 0.0 0.54 10.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized Strongylid L4 protein HTH_5 PF01022.20 EKX34420.1 - 0.18 11.7 0.0 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family CRM1_C PF08767.11 EKX34427.1 - 2.1e-110 368.9 1.4 2.1e-110 368.9 1.4 2.7 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 EKX34427.1 - 3.6e-32 111.5 13.0 3.6e-32 111.5 5.4 4.4 5 0 0 5 5 5 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EKX34427.1 - 8.9e-30 102.1 3.5 1.8e-29 101.2 2.5 2.2 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EKX34427.1 - 1.7e-24 85.7 0.2 6.8e-24 83.7 0.0 2.3 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 EKX34427.1 - 1.4e-18 66.1 0.8 4.6e-18 64.4 0.8 2.0 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 EKX34427.1 - 5.2e-13 48.7 2.3 1.1e-12 47.7 0.1 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain HP1451_C PF18472.1 EKX34427.1 - 0.043 13.8 0.0 0.16 12.0 0.0 1.9 1 0 0 1 1 1 0 HP1451 C-terminal domain Vac14_Fab1_bd PF12755.7 EKX34427.1 - 0.15 12.6 1.4 2.4 8.8 0.0 3.5 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region MIF4G PF02854.19 EKX34427.1 - 1.6 8.3 9.4 3.5 7.2 2.8 4.2 4 1 1 5 5 5 0 MIF4G domain RCC1 PF00415.18 EKX34430.1 - 9.7e-34 115.8 2.0 1.8e-13 50.9 0.5 3.0 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX34430.1 - 5.6e-18 64.2 8.9 9.3e-10 38.0 0.8 3.4 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat DUF4745 PF15923.5 EKX34432.1 - 0.11 12.5 3.5 0.34 10.9 2.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4745) DUF4407 PF14362.6 EKX34432.1 - 0.17 11.2 7.9 0.23 10.8 7.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 EKX34432.1 - 0.21 10.5 21.5 0.089 11.7 17.7 2.1 1 1 0 1 1 1 0 Spc7 kinetochore protein Rogdi_lz PF10259.9 EKX34432.1 - 0.36 10.2 8.9 0.63 9.5 8.9 1.5 1 1 0 1 1 1 0 Rogdi leucine zipper containing protein T3SSipB PF16535.5 EKX34432.1 - 0.7 10.4 9.4 0.22 12.0 2.0 2.4 1 1 1 2 2 2 0 Type III cell invasion protein SipB DUF1839 PF08893.10 EKX34432.1 - 0.81 8.8 4.1 0.47 9.6 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1839) KxDL PF10241.9 EKX34432.1 - 0.94 9.8 15.0 0.22 11.8 3.2 3.4 1 1 1 2 2 2 0 Uncharacterized conserved protein YlbD_coat PF14071.6 EKX34432.1 - 1.2 9.4 12.1 0.59 10.4 3.5 2.9 1 1 1 3 3 3 0 Putative coat protein RasGAP_C PF03836.15 EKX34432.1 - 1.8 8.7 17.5 65 3.7 17.5 2.2 1 1 0 1 1 1 0 RasGAP C-terminus IL2 PF00715.17 EKX34432.1 - 2.1 8.3 9.4 7.9 6.4 9.3 2.1 1 1 1 2 2 2 0 Interleukin 2 DUF4226 PF10774.9 EKX34432.1 - 2.7 8.3 7.0 1.1 9.5 1.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4226) DUF4404 PF14357.6 EKX34432.1 - 3.2 8.4 16.2 1.2 9.8 3.7 3.4 1 1 1 3 3 3 0 Domain of unknown function (DUF4404) CENP-Q PF13094.6 EKX34432.1 - 3.6 7.8 22.3 0.96 9.6 3.3 2.7 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit FUSC PF04632.12 EKX34432.1 - 4.1 5.8 5.0 6.8 5.1 5.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 EKX34432.1 - 5.1 7.1 14.8 0.17 11.9 2.4 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Glyco_transf_25 PF01755.17 EKX34433.1 - 2.1e-13 50.6 0.0 8e-13 48.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Glycos_transf_2 PF00535.26 EKX34433.1 - 4.1e-11 43.0 0.0 9.7e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EKX34433.1 - 1.2e-05 25.3 0.8 2.2e-05 24.4 0.8 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EKX34433.1 - 0.025 15.1 0.0 0.12 12.9 0.0 2.2 1 0 0 1 1 1 0 Glycosyl transferase family 2 MRP-S28 PF10213.9 EKX34433.1 - 0.096 13.1 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein Laminin_G_3 PF13385.6 EKX34434.1 - 5.9e-15 55.7 0.0 1.1e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily LCCL PF03815.19 EKX34434.1 - 2e-07 31.0 0.1 2e-07 31.0 0.1 3.5 3 0 0 3 3 3 1 LCCL domain Mito_fiss_reg PF05308.11 EKX34434.1 - 1.1 9.3 21.3 2.5 8.1 7.2 2.8 2 0 0 2 2 2 0 Mitochondrial fission regulator Myb_DNA-binding PF00249.31 EKX34435.1 - 9.1e-12 45.0 0.0 1.5e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EKX34435.1 - 0.00041 20.2 1.1 0.00066 19.5 0.6 1.5 1 1 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 EKX34435.1 - 0.0024 18.1 0.6 0.0049 17.1 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Pal1 PF08316.11 EKX34435.1 - 0.097 13.4 1.3 0.25 12.1 0.0 1.9 1 1 1 2 2 2 0 Pal1 cell morphology protein IPK PF03770.16 EKX34435.1 - 0.18 11.6 3.4 0.26 11.1 3.4 1.1 1 0 0 1 1 1 0 Inositol polyphosphate kinase LETM1 PF07766.13 EKX34436.1 - 5.6e-15 55.4 0.2 1.4e-14 54.1 0.2 1.6 1 0 0 1 1 1 1 LETM1-like protein CarS-like PF01864.17 EKX34436.1 - 0.081 12.9 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 CDP-archaeol synthase TBPIP PF07106.13 EKX34437.1 - 0.099 12.6 0.3 5.2 7.1 0.1 2.3 2 0 0 2 2 2 0 TBPIP/Hop2 winged helix domain DEAD PF00270.29 EKX34440.1 - 8.4e-44 149.4 0.0 1e-41 142.6 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX34440.1 - 3.4e-29 101.4 0.0 2e-27 95.7 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX34440.1 - 5.1e-07 29.9 0.1 4.2e-05 23.6 0.0 3.0 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Nitroreductase PF00881.24 EKX34440.1 - 0.027 14.5 0.0 0.067 13.2 0.0 1.6 1 0 0 1 1 1 0 Nitroreductase family UTP25 PF06862.12 EKX34440.1 - 0.038 12.8 0.0 0.28 9.9 0.0 2.0 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Dsh_C PF12316.8 EKX34440.1 - 0.38 11.1 5.4 0.71 10.2 5.4 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Zip PF02535.22 EKX34440.1 - 3.1 6.9 4.4 4.5 6.4 4.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Med19 PF10278.9 EKX34440.1 - 5.3 6.9 13.9 8.8 6.2 13.9 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 KIP1 PF07765.12 EKX34440.1 - 7.4 6.8 8.1 0.15 12.2 0.7 2.0 2 0 0 2 2 2 0 KIP1-like protein RNA_pol_Rpc4 PF05132.14 EKX34440.1 - 9.7 6.6 12.0 17 5.9 12.0 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 TPR_2 PF07719.17 EKX34441.1 - 1.1e-14 53.3 7.3 6.1e-06 26.0 0.1 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX34441.1 - 1e-12 47.3 6.2 0.0001 21.9 0.4 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX34441.1 - 2.3e-10 39.9 3.3 0.00014 21.8 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX34441.1 - 1.9e-07 31.6 0.3 0.00055 20.5 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX34441.1 - 1.5e-06 27.8 2.6 8.6e-05 22.1 0.2 2.6 3 0 0 3 3 3 1 TPR repeat Fis1_TPR_C PF14853.6 EKX34441.1 - 2.2e-06 27.7 1.3 2.5e-05 24.2 0.0 2.6 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 EKX34441.1 - 2e-05 24.6 0.5 0.002 18.2 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX34441.1 - 5.3e-05 23.6 2.0 0.011 16.2 0.5 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX34441.1 - 0.00013 22.4 0.9 0.66 10.7 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX34441.1 - 0.00018 21.7 1.6 0.0067 16.7 0.4 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX34441.1 - 0.00048 20.7 0.8 2 9.4 0.1 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX34441.1 - 0.0022 17.9 0.9 0.42 10.8 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX34441.1 - 0.0056 16.9 3.7 0.25 11.6 2.2 2.8 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 EKX34441.1 - 0.03 14.8 0.6 0.53 10.7 0.6 2.3 1 1 0 1 1 1 0 Bacterial transcriptional activator domain TPR_15 PF13429.6 EKX34441.1 - 0.065 12.4 0.4 7 5.8 0.0 2.3 1 1 0 2 2 2 0 Tetratricopeptide repeat 14-3-3 PF00244.20 EKX34441.1 - 0.071 12.6 0.0 0.083 12.4 0.0 1.1 1 0 0 1 1 1 0 14-3-3 protein Dynein_light PF01221.18 EKX34442.1 - 5.6e-44 148.4 2.0 6.2e-44 148.2 2.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ectatomin PF06457.11 EKX34442.1 - 0.15 12.0 0.2 0.25 11.3 0.2 1.3 1 0 0 1 1 1 0 Ectatomin Ank_4 PF13637.6 EKX34443.1 - 2e-17 63.3 0.1 7.3e-10 39.2 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX34443.1 - 3.1e-12 46.9 0.0 3.7e-08 33.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX34443.1 - 5e-12 45.8 0.1 1e-11 44.8 0.2 1.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX34443.1 - 7.4e-12 44.4 0.1 2e-06 27.7 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EKX34443.1 - 3.2e-09 36.8 1.0 2.6e-05 24.5 0.3 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ion_trans_2 PF07885.16 EKX34444.1 - 1.7e-07 31.1 3.1 1.7e-07 31.1 3.1 2.5 3 0 0 3 3 3 1 Ion channel SK_channel PF03530.14 EKX34444.1 - 5.9e-06 26.3 0.0 2e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 Calcium-activated SK potassium channel IQ PF00612.27 EKX34444.1 - 2.5 8.1 6.7 0.89 9.5 2.5 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif ETF PF01012.21 EKX34445.1 - 9.1e-51 172.3 1.0 1.1e-50 172.0 1.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain cobW PF02492.19 EKX34446.1 - 1.6e-43 148.3 0.9 2.1e-43 147.9 0.9 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EKX34446.1 - 9.8e-21 73.5 0.0 2e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.14 EKX34446.1 - 0.013 15.4 0.1 0.028 14.3 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 EKX34446.1 - 0.014 15.3 1.7 2.5 8.0 0.3 2.3 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 EKX34446.1 - 0.041 13.9 1.0 0.085 12.9 1.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Arf PF00025.21 EKX34446.1 - 0.5 9.8 2.8 25 4.3 0.1 2.9 3 1 0 3 3 3 0 ADP-ribosylation factor family PUB PF09409.10 EKX34447.1 - 2e-22 78.9 0.0 2.3e-12 46.7 0.0 2.4 2 0 0 2 2 2 2 PUB domain DUF4497 PF14924.6 EKX34448.1 - 0.021 15.3 1.9 0.024 15.1 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) DUF4919 PF16266.5 EKX34448.1 - 0.28 11.1 3.6 0.12 12.3 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4919) Sun2_CC2 PF18580.1 EKX34448.1 - 1.2 9.4 4.5 0.44 10.8 0.2 2.5 3 0 0 3 3 3 0 SUN2 coiled coil domain 2 UQ_con PF00179.26 EKX34450.1 - 2.7e-45 153.5 0.0 3.1e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EKX34450.1 - 0.015 15.0 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Kri1_C PF12936.7 EKX34451.1 - 9e-21 73.9 0.1 9e-21 73.9 0.1 6.4 7 0 0 7 7 7 1 KRI1-like family C-terminal Kri1 PF05178.12 EKX34451.1 - 9.6e-17 61.4 10.1 9.6e-17 61.4 10.1 7.8 5 4 3 8 8 8 1 KRI1-like family DUF4537 PF15057.6 EKX34451.1 - 0.066 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) DUF1325 PF07039.11 EKX34451.1 - 0.51 10.4 0.0 0.51 10.4 0.0 3.9 3 0 0 3 3 3 0 SGF29 tudor-like domain Aminotran_1_2 PF00155.21 EKX34452.1 - 3.4e-47 161.4 0.0 4e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EKX34452.1 - 3.8e-05 22.4 0.0 5e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF1967 PF09269.11 EKX34452.1 - 0.021 14.8 0.0 5.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) E1-E2_ATPase PF00122.20 EKX34453.1 - 1.7e-50 171.1 1.2 1.1e-49 168.4 0.1 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EKX34453.1 - 3.6e-44 150.7 4.4 3.6e-44 150.7 4.4 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EKX34453.1 - 1.8e-19 70.9 1.9 2.4e-18 67.2 1.9 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EKX34453.1 - 1.4e-17 63.1 0.0 3.6e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EKX34453.1 - 1.5e-15 57.0 0.0 4.3e-15 55.6 0.0 1.9 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EKX34453.1 - 6.4e-07 29.4 0.6 6.7e-05 22.8 0.5 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EKX34453.1 - 5e-05 23.8 0.1 0.00031 21.2 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3377 PF11857.8 EKX34453.1 - 0.23 11.4 1.8 0.81 9.7 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Ribosomal_S8e PF01201.22 EKX34454.1 - 5.3e-46 156.2 0.2 5.3e-46 156.2 0.2 2.1 1 1 1 2 2 2 2 Ribosomal protein S8e TMEM51 PF15345.6 EKX34454.1 - 0.0078 16.1 0.4 0.011 15.6 0.4 1.1 1 0 0 1 1 1 1 Transmembrane protein 51 Dus PF01207.17 EKX34455.1 - 3.1e-68 230.1 0.2 3.5e-68 230.0 0.2 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) NMO PF03060.15 EKX34455.1 - 5.8e-06 25.9 0.0 7.8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EKX34455.1 - 0.0024 16.9 0.0 0.0051 15.9 0.0 1.5 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain G3P_antiterm PF04309.12 EKX34455.1 - 0.006 16.0 0.0 0.012 15.0 0.0 1.4 2 0 0 2 2 2 1 Glycerol-3-phosphate responsive antiterminator FMN_dh PF01070.18 EKX34455.1 - 0.012 14.6 0.0 0.023 13.7 0.0 1.5 1 1 0 1 1 1 0 FMN-dependent dehydrogenase DHO_dh PF01180.21 EKX34455.1 - 0.014 14.7 0.0 0.087 12.0 0.0 1.9 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 EKX34455.1 - 0.017 14.6 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein Lipase_GDSL_2 PF13472.6 EKX34455.1 - 0.081 13.3 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family TMP-TENI PF02581.17 EKX34455.1 - 0.093 12.1 0.0 0.71 9.2 0.0 2.1 2 0 0 2 2 2 0 Thiamine monophosphate synthase DUF2574 PF10836.8 EKX34455.1 - 0.17 11.7 0.0 3.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2574) VEFS-Box PF09733.9 EKX34457.1 - 2.1e-30 105.3 2.4 2.3e-30 105.2 2.4 1.0 1 0 0 1 1 1 1 VEFS-Box of polycomb protein PIN_3 PF13470.6 EKX34457.1 - 0.015 16.0 0.0 0.017 15.9 0.0 1.2 1 0 0 1 1 1 0 PIN domain XS PF03468.14 EKX34457.1 - 0.049 13.9 0.0 0.056 13.8 0.0 1.1 1 0 0 1 1 1 0 XS domain LRR_9 PF14580.6 EKX34458.1 - 3.1e-11 43.1 13.5 1.7e-10 40.7 6.4 3.0 2 1 0 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 EKX34458.1 - 9.4e-08 32.2 16.3 0.0013 19.1 3.6 3.9 1 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX34458.1 - 8.4e-07 28.7 13.4 0.0018 18.0 2.0 3.3 2 2 0 3 3 3 2 Leucine rich repeat TPR_2 PF07719.17 EKX34459.1 - 0.086 13.0 0.2 0.086 13.0 0.2 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX34459.1 - 0.73 10.1 3.9 0.57 10.4 0.6 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EKX34459.1 - 1.2 9.9 18.8 16 6.2 2.5 6.0 4 2 1 5 5 5 0 Tetratricopeptide repeat Ephrin_rec_like PF07699.13 EKX34460.1 - 4.7e-05 23.1 24.8 0.013 15.3 4.4 3.7 3 0 0 3 3 3 2 Putative ephrin-receptor like Hydrolase_4 PF12146.8 EKX34460.1 - 0.00068 19.0 0.0 0.0019 17.5 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EKX34460.1 - 0.00092 19.9 0.0 0.0021 18.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EKX34460.1 - 0.0076 15.9 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold cEGF PF12662.7 EKX34460.1 - 0.2 11.6 6.5 0.18 11.8 4.1 2.3 2 0 0 2 2 2 0 Complement Clr-like EGF-like EGF_2 PF07974.13 EKX34460.1 - 1 9.8 5.3 2.2 8.7 0.1 2.9 2 0 0 2 2 2 0 EGF-like domain EGF_MSP1_1 PF12946.7 EKX34460.1 - 8.1 6.6 8.2 1.9 8.6 1.0 3.2 3 0 0 3 3 3 0 MSP1 EGF domain 1 VWA_3 PF13768.6 EKX34461.1 - 1.8e-09 37.7 0.1 2.3e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EKX34461.1 - 3e-06 27.6 0.0 3.4e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EKX34461.1 - 0.00049 20.7 0.0 0.0011 19.6 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Copine PF07002.16 EKX34461.1 - 0.00053 19.5 0.0 0.0018 17.8 0.0 1.7 1 1 1 2 2 2 1 Copine HILPDA PF15220.6 EKX34461.1 - 0.02 15.0 0.1 0.032 14.4 0.1 1.3 1 0 0 1 1 1 0 Hypoxia-inducible lipid droplet-associated DUF4125 PF13526.6 EKX34463.1 - 0.032 13.8 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4125) Eno-Rase_NADH_b PF12242.8 EKX34464.1 - 0.11 12.3 2.3 1.8 8.4 0.1 2.7 1 1 2 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PNRC PF15365.6 EKX34464.1 - 2 8.3 6.3 13 5.7 0.5 2.7 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator motif Transglut_core PF01841.19 EKX34467.1 - 6.1e-16 58.9 0.7 1.2e-15 57.9 0.1 1.7 2 0 0 2 2 2 1 Transglutaminase-like superfamily DUF553 PF04473.12 EKX34467.1 - 0.00032 20.3 0.0 0.049 13.2 0.0 2.3 1 1 1 2 2 2 2 Transglutaminase-like domain Ank_2 PF12796.7 EKX34468.1 - 1.5e-34 118.4 7.5 1.5e-09 38.3 0.7 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX34468.1 - 3.9e-30 103.8 16.6 1e-10 41.9 0.0 5.6 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX34468.1 - 1.9e-26 89.2 6.1 0.0011 19.3 0.0 7.7 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 EKX34468.1 - 6.3e-22 77.4 9.5 3.1e-07 30.5 0.3 6.2 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EKX34468.1 - 3.2e-21 74.8 10.1 0.0053 17.2 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat HTH_18 PF12833.7 EKX34468.1 - 0.031 14.5 0.8 1.4 9.2 0.0 3.2 4 0 0 4 4 4 0 Helix-turn-helix domain Humanin PF15040.6 EKX34468.1 - 0.24 10.9 1.2 2 7.9 0.0 2.9 3 0 0 3 3 3 0 Humanin family BCL_N PF04714.13 EKX34469.1 - 0.11 12.5 0.2 1 9.5 0.2 2.8 1 0 0 1 1 1 0 BCL7, N-terminal conserver region SlyX PF04102.12 EKX34469.1 - 0.18 12.5 0.0 0.18 12.5 0.0 9.1 8 4 1 10 10 10 0 SlyX Collagen PF01391.18 EKX34471.1 - 2.2e-20 72.1 92.3 9.6e-10 38.1 29.1 4.5 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Patatin PF01734.22 EKX34472.1 - 5.5e-08 33.2 1.2 9.4e-08 32.5 1.2 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase SNase PF00565.17 EKX34473.1 - 3.7e-71 236.5 0.6 2.7e-16 60.0 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 EKX34473.1 - 1.3e-19 70.4 0.0 2.7e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 EKX34473.1 - 0.00018 20.9 0.0 0.00038 19.8 0.0 1.5 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Agenet PF05641.12 EKX34473.1 - 0.012 16.0 0.0 0.077 13.5 0.0 2.4 2 0 0 2 2 2 0 Agenet domain PI3_PI4_kinase PF00454.27 EKX34474.1 - 5.9e-38 131.1 0.1 1.3e-35 123.4 0.1 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 EKX34474.1 - 0.00035 20.0 0.0 0.0009 18.7 0.0 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4135) ATP-gua_Ptrans PF00217.19 EKX34475.1 - 5.6e-104 346.2 0.0 6.8e-63 212.0 0.0 2.4 2 0 0 2 2 2 2 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 EKX34475.1 - 1.6e-16 60.4 0.0 5.9e-16 58.6 0.0 2.0 3 0 0 3 3 3 1 ATP:guanido phosphotransferase, N-terminal domain AIRS_C PF02769.22 EKX34475.1 - 0.0062 16.7 0.7 5.2 7.2 0.1 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain Sec7_N PF12783.7 EKX34475.1 - 0.032 14.1 0.0 11 5.9 0.0 2.6 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF4993 PF16384.5 EKX34475.1 - 0.12 11.4 0.0 14 4.6 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function FERM_N PF09379.10 EKX34475.1 - 0.15 12.0 0.2 29 4.7 0.0 2.5 2 0 0 2 2 2 0 FERM N-terminal domain ComX PF05952.12 EKX34475.1 - 0.88 9.6 2.3 36 4.4 0.2 2.4 2 0 0 2 2 2 0 Bacillus competence pheromone ComX 60KD_IMP PF02096.20 EKX34476.1 - 5.9e-39 133.6 0.1 1e-38 132.9 0.1 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein Wzy_C PF04932.15 EKX34479.1 - 0.0096 15.6 0.1 0.016 14.8 0.1 1.5 1 0 0 1 1 1 1 O-Antigen ligase Jiraiya PF15038.6 EKX34479.1 - 0.32 10.4 7.7 0.58 9.6 7.6 1.4 1 1 0 1 1 1 0 Jiraiya DUF2254 PF10011.9 EKX34479.1 - 0.36 9.6 1.3 0.47 9.2 1.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF975 PF06161.11 EKX34479.1 - 0.56 10.0 9.1 1 9.1 8.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF975) YibE_F PF07907.11 EKX34479.1 - 3.6 7.0 12.2 0.11 12.0 4.9 1.9 2 0 0 2 2 2 0 YibE/F-like protein DUF819 PF05684.12 EKX34480.1 - 4.7e-48 164.1 21.1 1.1e-47 162.9 21.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF819) Tubulin PF00091.25 EKX34481.1 - 9e-70 234.9 0.0 1.3e-69 234.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EKX34481.1 - 9.7e-43 145.3 0.0 1.6e-42 144.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EKX34481.1 - 2.5e-05 24.6 0.0 4.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 EKX34481.1 - 2.7e-05 23.6 0.0 4.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin like Tubulin_3 PF14881.6 EKX34481.1 - 0.032 13.9 0.0 0.087 12.5 0.0 1.7 2 0 0 2 2 2 0 Tubulin domain Holin_BhlA PF10960.8 EKX34482.1 - 0.063 13.3 2.9 4.1 7.4 0.0 2.4 2 0 0 2 2 2 0 BhlA holin family DUF2072 PF09845.9 EKX34482.1 - 0.072 13.4 1.8 3.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Zn-ribbon containing protein TPR_19 PF14559.6 EKX34484.1 - 0.00033 21.1 0.1 0.005 17.3 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX34484.1 - 0.0014 19.3 2.4 1.3 10.1 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 EKX34484.1 - 0.0027 17.0 0.2 0.015 14.5 0.2 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat Glyco_transf_41 PF13844.6 EKX34484.1 - 0.0089 14.5 0.0 0.012 14.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 41 TPR_16 PF13432.6 EKX34484.1 - 0.0098 16.5 1.8 0.12 13.1 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX34484.1 - 0.03 14.4 0.8 6.9 7.0 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_S7 PF00177.21 EKX34484.1 - 0.035 13.7 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e TPR_12 PF13424.6 EKX34484.1 - 0.71 10.2 3.5 2.6 8.4 0.3 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Pilus_CpaD PF09476.10 EKX34486.1 - 0.022 14.5 0.1 0.027 14.2 0.1 1.1 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) DUF3400 PF11880.8 EKX34488.1 - 0.032 13.7 0.1 0.066 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) DUF2284 PF10050.9 EKX34489.1 - 0.089 12.5 1.0 0.2 11.4 0.3 1.7 1 1 0 2 2 2 0 Predicted metal-binding protein (DUF2284) Bac_GDH PF05088.12 EKX34489.1 - 0.27 8.7 3.0 0.35 8.3 3.0 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase Sun2_CC2 PF18580.1 EKX34489.1 - 0.29 11.4 3.9 1.1 9.5 0.2 2.5 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 TipAS PF07739.13 EKX34489.1 - 0.92 10.1 3.3 1.7 9.2 1.0 2.1 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain TTL PF03133.15 EKX34490.1 - 3.3e-56 190.6 0.0 2.5e-54 184.4 0.0 2.3 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EKX34490.1 - 4.3e-08 32.7 0.1 0.0059 15.9 0.0 3.5 3 1 0 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EKX34490.1 - 2e-06 27.3 0.0 0.026 13.8 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp RimK PF08443.11 EKX34490.1 - 0.00013 21.7 0.0 0.0031 17.1 0.0 2.2 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.13 EKX34490.1 - 0.028 14.0 0.0 6.6 6.2 0.0 2.3 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus GSH-S_ATP PF02955.16 EKX34490.1 - 0.034 13.6 0.0 0.063 12.7 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_3 PF02655.14 EKX34490.1 - 0.062 13.3 0.0 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain TetR_C_12 PF16914.5 EKX34490.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial transcriptional repressor C-terminal Far-17a_AIG1 PF04750.14 EKX34491.1 - 7.4e-06 25.4 6.1 1.2e-05 24.7 6.1 1.3 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein SR-25 PF10500.9 EKX34491.1 - 0.42 10.2 17.8 0.6 9.7 17.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Dicty_REP PF05086.12 EKX34491.1 - 0.54 8.2 6.1 0.66 7.9 6.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RFXA_RFXANK_bdg PF15289.6 EKX34491.1 - 2.4 8.5 14.6 3.4 8.0 14.6 1.2 1 0 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain MAP PF03642.13 EKX34492.1 - 0.021 15.1 0.0 11 6.4 0.0 2.3 2 0 0 2 2 2 0 MAP domain LURAP PF14854.6 EKX34492.1 - 0.099 12.6 0.3 15 5.6 0.0 2.4 2 0 0 2 2 2 0 Leucine rich adaptor protein Mob1_phocein PF03637.17 EKX34502.1 - 8.7e-24 84.4 0.5 1.1e-23 84.1 0.5 1.0 1 0 0 1 1 1 1 Mob1/phocein family Arm PF00514.23 EKX34503.1 - 7.6e-41 136.9 29.3 9.2e-09 35.1 0.1 7.8 7 1 0 7 7 7 7 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EKX34503.1 - 3.5e-07 30.2 4.7 0.16 12.0 0.1 4.9 2 1 4 6 6 6 5 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 EKX34503.1 - 1.9e-05 24.2 0.4 0.021 14.3 0.0 3.4 2 1 3 5 5 5 2 Armadillo-like HEAT PF02985.22 EKX34503.1 - 1.9e-05 24.5 16.5 0.6 10.5 0.0 5.3 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 EKX34503.1 - 5.6e-05 23.5 16.8 0.013 15.8 4.2 3.7 1 1 3 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 EKX34503.1 - 0.0018 18.7 21.3 0.38 11.3 0.3 4.9 2 2 3 5 5 5 3 HEAT-like repeat Cnd1 PF12717.7 EKX34503.1 - 0.021 14.9 1.2 0.81 9.7 0.2 2.8 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 BRCA-2_OB3 PF09104.10 EKX34503.1 - 0.027 14.1 0.2 1.5 8.4 0.0 2.5 2 0 0 2 2 2 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 5_nucleotid_C PF02872.18 EKX34505.1 - 6e-23 81.8 0.0 1.7e-22 80.3 0.0 1.7 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EKX34505.1 - 2.5e-09 37.9 0.0 3.5e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ATP-gua_PtransN PF02807.15 EKX34505.1 - 0.18 12.2 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 ATP:guanido phosphotransferase, N-terminal domain RCC1 PF00415.18 EKX34506.1 - 1.6e-36 124.7 15.7 5.1e-14 52.6 1.4 4.5 4 1 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX34506.1 - 1.1e-12 47.4 22.7 0.00027 20.7 0.7 4.4 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 EKX34506.1 - 5.5e-09 35.8 1.3 9.9e-09 35.0 1.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EKX34506.1 - 9.2e-07 28.6 0.6 1.7e-06 27.7 0.6 1.5 1 0 0 1 1 1 1 F-box domain Thioredoxin_8 PF13905.6 EKX34508.1 - 4e-61 203.4 0.0 1.9e-31 108.3 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 EKX34508.1 - 1e-19 70.7 0.0 5.2e-12 45.7 0.0 2.3 2 0 0 2 2 2 2 Redoxin AhpC-TSA PF00578.21 EKX34508.1 - 4.4e-18 65.4 0.0 2.9e-08 33.6 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin PF00085.20 EKX34508.1 - 1.2e-17 63.7 0.3 1.2e-05 25.3 0.3 4.4 2 2 2 4 4 4 3 Thioredoxin Thioredoxin_2 PF13098.6 EKX34508.1 - 3.6e-17 62.8 0.0 1.2e-08 35.4 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EKX34508.1 - 9.8e-07 28.9 0.0 0.018 15.2 0.0 2.9 2 2 0 2 2 2 2 Thioredoxin-like DUF953 PF06110.11 EKX34508.1 - 0.00035 20.2 2.2 0.43 10.2 0.1 4.4 3 2 0 3 3 3 1 Eukaryotic protein of unknown function (DUF953) SCO1-SenC PF02630.14 EKX34508.1 - 0.00065 19.6 0.1 1.5 8.8 0.0 3.0 3 0 0 3 3 3 2 SCO1/SenC Thioredoxin_9 PF14595.6 EKX34508.1 - 0.0011 18.7 0.2 2.3 8.0 0.1 4.1 2 2 1 3 3 3 1 Thioredoxin Glutaredoxin PF00462.24 EKX34508.1 - 0.0028 17.8 2.7 0.25 11.6 0.1 3.3 2 1 0 2 2 2 1 Glutaredoxin NADH_4Fe-4S PF10589.9 EKX34508.1 - 0.014 15.4 0.0 4.9 7.3 0.0 2.7 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region TraF PF13728.6 EKX34508.1 - 0.022 14.6 0.0 0.31 10.8 0.0 2.5 2 1 0 2 2 2 0 F plasmid transfer operon protein HyaE PF07449.11 EKX34508.1 - 0.026 14.5 0.0 0.85 9.6 0.0 2.6 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Toxin-deaminase PF14424.6 EKX34508.1 - 0.079 13.1 0.0 11 6.1 0.0 2.7 2 0 0 2 2 2 0 The BURPS668_1122 family of deaminases Acetyltransf_7 PF13508.7 EKX34509.1 - 2.1e-10 40.8 0.0 3.2e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EKX34509.1 - 2.2e-10 40.8 0.0 2.7e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EKX34509.1 - 1.5e-05 24.9 0.0 2.7e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EKX34509.1 - 0.003 17.6 0.0 0.01 16.0 0.0 1.8 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase MOZ_SAS PF01853.18 EKX34509.1 - 0.036 13.7 0.0 0.047 13.3 0.0 1.1 1 0 0 1 1 1 0 MOZ/SAS family Acetyltransf_15 PF17013.5 EKX34509.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase GNT-I PF03071.15 EKX34511.1 - 0.0037 16.1 0.0 0.051 12.3 0.1 2.1 2 0 0 2 2 2 2 GNT-I family Xylo_C PF12529.8 EKX34513.1 - 0.033 13.8 0.0 0.049 13.3 0.0 1.3 1 1 0 1 1 1 0 Xylosyltransferase C terminal DUF4848 PF16140.5 EKX34513.1 - 0.088 12.4 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4848) Aldedh PF00171.22 EKX34515.1 - 4.6e-141 470.5 0.0 6.2e-141 470.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EKX34515.1 - 0.0084 15.6 0.1 0.083 12.3 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Inhibitor_I42 PF09394.10 EKX34516.1 - 6.2e-07 29.8 0.1 1.3e-06 28.7 0.1 1.8 1 1 0 1 1 1 1 Chagasin family peptidase inhibitor I42 PGK PF00162.19 EKX34517.1 - 4.6e-162 539.3 0.1 5.4e-162 539.0 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Radical_SAM PF04055.21 EKX34519.1 - 1.1e-13 51.9 0.0 2.4e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 EKX34519.1 - 0.062 13.4 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 4Fe-4S single cluster domain AAA PF00004.29 EKX34520.1 - 1.5e-25 90.2 0.0 7.1e-25 88.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EKX34520.1 - 0.00024 21.1 0.2 0.0047 16.9 0.0 2.8 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EKX34520.1 - 0.00068 20.1 2.8 0.0092 16.4 2.3 2.8 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 EKX34520.1 - 0.0019 17.9 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein ABC_tran PF00005.27 EKX34520.1 - 0.0022 18.5 0.0 0.67 10.5 0.0 3.1 2 2 0 2 2 2 1 ABC transporter AAA_33 PF13671.6 EKX34520.1 - 0.0025 18.0 0.0 0.0073 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EKX34520.1 - 0.0029 17.9 1.2 0.79 10.0 0.1 3.0 1 1 2 3 3 3 1 AAA domain AAA_25 PF13481.6 EKX34520.1 - 0.0035 16.9 1.2 0.01 15.4 0.4 2.0 1 1 1 2 2 2 1 AAA domain NACHT PF05729.12 EKX34520.1 - 0.0057 16.6 2.5 0.25 11.2 0.0 3.0 2 1 1 3 3 3 1 NACHT domain AAA_23 PF13476.6 EKX34520.1 - 0.052 14.1 0.1 2.8 8.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 EKX34520.1 - 0.067 12.6 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EKX34520.1 - 0.079 13.5 0.0 0.26 11.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 EKX34520.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 EKX34520.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain CvfB_WH PF17783.1 EKX34521.1 - 6.6e-21 73.9 0.7 1.3e-20 72.9 0.7 1.6 1 0 0 1 1 1 1 CvfB-like winged helix domain DUF2967 PF11179.8 EKX34522.1 - 0.61 8.1 8.7 0.74 7.8 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Phage_Mu_F PF04233.14 EKX34523.1 - 0.18 12.5 1.9 0.3 11.8 1.9 1.4 1 0 0 1 1 1 0 Phage Mu protein F like protein AXH PF08517.12 EKX34524.1 - 0.31 11.6 1.9 1.2 9.7 1.9 1.9 1 1 0 1 1 1 0 Ataxin-1 and HBP1 module (AXH) DUF2025 PF09634.10 EKX34525.1 - 0.091 12.8 0.0 0.76 9.8 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2025) RRM_3 PF08777.11 EKX34525.1 - 0.19 11.8 0.1 11 6.2 0.0 2.1 1 1 1 2 2 2 0 RNA binding motif CarbopepD_reg_2 PF13715.6 EKX34525.1 - 0.19 11.8 0.0 17 5.5 0.0 2.1 2 0 0 2 2 2 0 CarboxypepD_reg-like domain rRNA_methylase PF06962.12 EKX34525.1 - 0.2 11.6 0.0 7.4 6.5 0.0 2.0 1 1 1 2 2 2 0 Putative rRNA methylase Kinesin PF00225.23 EKX34527.1 - 6.3e-85 285.0 0.6 9.6e-52 176.0 0.3 2.0 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 EKX34527.1 - 1.3e-33 116.0 0.3 2.6e-27 95.6 0.0 2.4 1 1 1 2 2 2 2 Microtubule binding PhoH PF02562.16 EKX34527.1 - 0.015 14.8 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 EKX34527.1 - 0.046 14.0 0.3 0.21 11.8 0.1 2.1 1 1 1 2 2 2 0 AAA domain DEAD PF00270.29 EKX34527.1 - 0.054 13.2 0.0 0.086 12.6 0.0 1.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_30 PF13604.6 EKX34527.1 - 0.063 13.0 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain HALZ PF02183.18 EKX34527.1 - 0.11 12.8 1.3 0.2 11.9 1.3 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper GIT_CC PF16559.5 EKX34528.1 - 0.022 14.6 2.4 0.045 13.6 2.4 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor V_ATPase_I PF01496.19 EKX34528.1 - 0.051 11.5 4.7 0.056 11.4 4.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pkinase PF00069.25 EKX34529.1 - 3.2e-59 200.4 0.0 3.9e-59 200.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX34529.1 - 2.3e-29 102.5 0.0 3.1e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX34529.1 - 3.7e-06 26.5 0.0 4.5e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EKX34529.1 - 2.9e-05 24.1 0.6 0.0013 18.7 0.2 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX34529.1 - 6.1e-05 22.5 0.0 8.6e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EKX34529.1 - 0.041 12.8 0.0 0.065 12.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EKX34529.1 - 0.057 12.2 0.0 0.14 10.9 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Choline_kinase PF01633.20 EKX34529.1 - 0.078 12.6 0.0 0.17 11.4 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase ABC1 PF03109.16 EKX34529.1 - 0.097 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 ABC1 family NusG PF02357.19 EKX34531.1 - 4.1e-17 62.5 0.1 8.4e-17 61.5 0.1 1.5 2 0 0 2 2 2 1 Transcription termination factor nusG KOW PF00467.29 EKX34531.1 - 0.00014 21.7 0.7 0.00031 20.6 0.7 1.6 1 0 0 1 1 1 1 KOW motif R-HINP1I PF11463.8 EKX34531.1 - 0.04 13.4 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 R.HinP1I restriction endonuclease RHD_DNA_bind PF00554.22 EKX34531.1 - 0.062 13.2 0.0 0.084 12.8 0.0 1.2 1 0 0 1 1 1 0 Rel homology DNA-binding domain DUF1640 PF07798.11 EKX34532.1 - 0.094 12.8 8.1 0.23 11.5 8.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) TolA_bind_tri PF16331.5 EKX34532.1 - 0.11 12.6 15.4 0.39 10.8 0.9 3.1 2 1 1 3 3 3 0 TolA binding protein trimerisation Prominin PF05478.11 EKX34532.1 - 0.15 10.0 4.9 0.22 9.4 4.9 1.3 1 0 0 1 1 1 0 Prominin HALZ PF02183.18 EKX34532.1 - 0.21 11.8 9.5 1.3 9.3 0.1 3.1 2 1 1 3 3 3 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 EKX34532.1 - 0.62 10.2 19.6 1.4 9.1 5.3 3.7 3 0 0 3 3 3 0 Basic region leucine zipper bZIP_1 PF00170.21 EKX34532.1 - 0.69 10.0 19.0 0.086 13.0 2.8 3.5 2 1 1 3 3 3 0 bZIP transcription factor SlyX PF04102.12 EKX34532.1 - 0.79 10.4 11.8 4 8.1 0.6 3.6 3 0 0 3 3 3 0 SlyX AvrLm4-7 PF18661.1 EKX34532.1 - 2.2 9.4 4.8 22 6.2 0.0 3.1 3 1 0 3 3 3 0 Avirulence Effector AvrLm4-7 UPF0561 PF10573.9 EKX34532.1 - 4.1 7.5 6.6 40 4.4 6.2 2.6 1 1 1 2 2 2 0 Uncharacterised protein family UPF0561 Ax_dynein_light PF10211.9 EKX34532.1 - 4.9 7.1 25.3 0.036 14.0 13.4 2.7 2 1 1 3 3 3 0 Axonemal dynein light chain BLOC1_2 PF10046.9 EKX34532.1 - 8.3 6.8 13.8 78 3.7 8.8 3.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tup_N PF08581.10 EKX34532.1 - 9.7 6.6 17.0 4.8 7.6 0.0 3.7 4 1 0 4 4 4 0 Tup N-terminal Jnk-SapK_ap_N PF09744.9 EKX34533.1 - 0.00092 19.5 9.5 0.00092 19.5 9.5 6.8 4 1 3 7 7 7 3 JNK_SAPK-associated protein-1 DUF2070 PF09843.9 EKX34533.1 - 0.18 10.1 0.1 0.32 9.2 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TRAF_BIRC3_bd PF16673.5 EKX34533.1 - 0.57 10.0 11.6 0.71 9.7 0.7 4.8 4 0 0 4 4 4 0 TNF receptor-associated factor BIRC3 binding domain TMF_TATA_bd PF12325.8 EKX34534.1 - 0.004 17.4 11.0 0.004 17.4 11.0 1.6 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding YabA PF06156.13 EKX34534.1 - 0.019 15.6 6.0 0.019 15.6 6.0 2.2 1 1 2 3 3 3 0 Initiation control protein YabA DUF5347 PF17282.2 EKX34534.1 - 0.069 13.5 0.5 0.16 12.3 0.5 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5347) DUF4201 PF13870.6 EKX34534.1 - 0.13 12.0 14.3 0.099 12.4 12.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Seadorna_VP6 PF07407.11 EKX34534.1 - 0.14 11.0 0.9 0.19 10.6 0.9 1.2 1 0 0 1 1 1 0 Seadornavirus VP6 protein CENP-H PF05837.12 EKX34534.1 - 2.3 8.7 15.6 0.24 11.8 9.5 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Csm1_N PF18504.1 EKX34534.1 - 2.5 8.5 10.7 8.3 6.8 2.2 2.6 2 0 0 2 2 2 0 Csm1 N-terminal domain APG6_N PF17675.1 EKX34534.1 - 3.9 8.0 17.3 6.8 7.2 17.3 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 EKX34534.1 - 5.4 6.9 10.1 0.52 10.1 2.0 2.6 1 1 2 3 3 3 0 Septum formation initiator RhoGEF67_u1 PF16615.5 EKX34534.1 - 6.3 7.4 14.9 2.9 8.5 3.5 3.5 3 1 0 3 3 3 0 Unstructured region one on RhoGEF 6 and 7 GNT-I PF03071.15 EKX34535.1 - 1.2e-10 40.8 0.1 5.6e-10 38.6 0.1 2.0 2 0 0 2 2 2 1 GNT-I family AAA_11 PF13086.6 EKX34536.1 - 1.5e-05 24.9 6.1 0.0001 22.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EKX34536.1 - 0.019 14.7 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EKX34536.1 - 0.028 14.8 0.0 0.076 13.4 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EKX34536.1 - 0.042 13.4 0.1 0.19 11.3 0.0 2.1 2 1 1 3 3 3 0 AAA domain AAA_7 PF12775.7 EKX34536.1 - 0.053 13.0 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 EKX34536.1 - 0.057 13.7 0.0 0.27 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 EKX34536.1 - 0.078 13.0 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 EKX34536.1 - 0.087 13.4 0.1 0.36 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2312 PF10073.9 EKX34536.1 - 0.11 12.2 13.1 0.2 11.3 4.1 3.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) AAA_16 PF13191.6 EKX34536.1 - 0.11 12.9 0.8 0.31 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain ATPase PF06745.13 EKX34536.1 - 0.26 10.6 2.6 9.4 5.5 0.0 3.2 2 1 2 4 4 4 0 KaiC APG6_N PF17675.1 EKX34536.1 - 0.26 11.8 13.9 7.7 7.1 13.9 2.5 1 1 0 1 1 1 0 Apg6 coiled-coil region ADIP PF11559.8 EKX34536.1 - 0.28 11.3 6.9 4.6 7.3 6.8 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding HlyD_2 PF12700.7 EKX34536.1 - 0.34 9.6 5.7 0.52 9.0 5.7 1.2 1 0 0 1 1 1 0 HlyD family secretion protein DUF3584 PF12128.8 EKX34536.1 - 0.57 7.6 9.4 0.83 7.1 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 EKX34536.1 - 0.58 10.2 10.5 1.1 9.3 10.5 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein M PF02370.16 EKX34536.1 - 0.75 10.6 12.7 6.8 7.6 2.6 3.4 2 0 0 2 2 2 0 M protein repeat Spc7 PF08317.11 EKX34536.1 - 4.4 6.1 13.8 4 6.2 6.7 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4407 PF14362.6 EKX34536.1 - 5.3 6.3 8.2 8 5.7 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4140 PF13600.6 EKX34536.1 - 5.5 7.5 7.5 3.7 8.0 0.1 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) AAA_13 PF13166.6 EKX34536.1 - 9.1 4.8 9.1 4.3 5.8 3.0 2.1 1 1 1 2 2 2 0 AAA domain Mem_trans PF03547.18 EKX34537.1 - 0.13 10.7 0.3 0.14 10.5 0.3 1.2 1 0 0 1 1 1 0 Membrane transport protein PA26 PF04636.13 EKX34537.1 - 2.1 7.2 4.3 3 6.6 4.3 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) PrmC_N PF17827.1 EKX34539.1 - 1.8e-13 50.9 1.8 1.8e-13 50.9 1.8 1.9 2 0 0 2 2 1 1 PrmC N-terminal domain MTS PF05175.14 EKX34539.1 - 3.1e-06 26.9 0.0 4.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EKX34539.1 - 0.00028 21.5 0.0 0.00052 20.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EKX34539.1 - 0.00041 19.8 0.0 0.00064 19.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 EKX34539.1 - 0.00047 20.0 0.0 0.0011 18.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX34539.1 - 0.00062 19.6 0.0 0.00086 19.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 EKX34539.1 - 0.0015 17.6 0.0 0.0035 16.4 0.0 1.5 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Rsm22 PF09243.10 EKX34539.1 - 0.029 13.7 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_24 PF13578.6 EKX34539.1 - 0.035 15.1 0.0 0.11 13.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.18 EKX34539.1 - 0.037 13.7 0.0 0.082 12.6 0.0 1.5 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 PRMT5 PF05185.16 EKX34539.1 - 0.044 13.6 0.0 0.066 13.1 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Cons_hypoth95 PF03602.15 EKX34539.1 - 0.047 13.3 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 EKX34539.1 - 0.05 13.2 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DUF2605 PF10792.9 EKX34539.1 - 0.067 13.1 0.3 16 5.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2605) Methyltransf_28 PF02636.17 EKX34539.1 - 0.22 11.1 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase N6_Mtase PF02384.16 EKX34539.1 - 0.24 10.7 0.0 0.29 10.3 0.0 1.1 1 0 0 1 1 1 0 N-6 DNA Methylase EF-hand_8 PF13833.6 EKX34540.1 - 3.7e-23 81.1 0.3 4e-12 45.8 0.1 4.0 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 EKX34540.1 - 2.9e-21 73.4 0.5 9.1e-09 34.3 1.0 4.4 4 1 1 5 5 5 3 EF hand EF-hand_7 PF13499.6 EKX34540.1 - 3.9e-17 62.5 0.4 3.4e-12 46.6 0.4 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX34540.1 - 3.6e-14 51.4 1.8 5.4e-05 22.8 0.2 4.4 5 1 0 5 5 5 2 EF-hand domain EF-hand_9 PF14658.6 EKX34540.1 - 5.1e-10 39.5 0.0 1.8e-06 28.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EKX34540.1 - 6.8e-09 34.8 6.2 0.00026 20.3 1.0 3.4 3 1 1 4 4 4 2 EF hand EF-hand_4 PF12763.7 EKX34540.1 - 0.0048 16.8 0.0 0.018 15.0 0.0 1.8 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand TerB PF05099.13 EKX34540.1 - 0.0083 16.1 0.0 0.18 11.8 0.0 2.6 2 1 1 3 3 3 1 Tellurite resistance protein TerB DUF3024 PF11225.8 EKX34540.1 - 0.08 13.2 0.0 16 5.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3024) UPF0154 PF03672.13 EKX34540.1 - 0.099 12.7 0.1 0.58 10.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Sugarporin_N PF11471.8 EKX34541.1 - 0.0045 16.9 0.4 22 5.1 0.0 3.4 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension DUF2730 PF10805.8 EKX34541.1 - 0.02 15.0 0.2 2.1 8.5 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) TRAF_BIRC3_bd PF16673.5 EKX34541.1 - 0.021 14.6 1.5 0.044 13.6 1.0 1.9 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain MYO10_CC PF16735.5 EKX34541.1 - 0.045 13.8 1.1 0.13 12.3 1.1 1.8 1 0 0 1 1 1 0 Unconventional myosin-X coiled coil domain PepSY_TM PF03929.16 EKX34541.1 - 0.054 13.2 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 PepSY-associated TM region T3SSipB PF16535.5 EKX34541.1 - 0.079 13.4 0.1 0.13 12.7 0.1 1.2 1 0 0 1 1 1 0 Type III cell invasion protein SipB DUF1043 PF06295.12 EKX34541.1 - 0.22 11.5 0.9 11 6.1 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) ABC_tran_Xtn PF12848.7 EKX34541.1 - 0.32 11.1 3.1 0.15 12.1 0.7 1.7 2 0 0 2 2 2 0 ABC transporter Tropomyosin_1 PF12718.7 EKX34541.1 - 0.86 9.8 7.8 1 9.5 2.7 2.3 1 1 0 2 2 2 0 Tropomyosin like ABC_tran_CTD PF16326.5 EKX34541.1 - 1 9.6 7.6 69 3.8 7.7 2.8 1 1 0 1 1 1 0 ABC transporter C-terminal domain DMPK_coil PF08826.10 EKX34541.1 - 2.7 8.2 5.6 3 8.0 0.9 2.4 1 1 1 2 2 2 0 DMPK coiled coil domain like HEAT PF02985.22 EKX34542.1 - 6.4e-07 29.1 12.6 2.4 8.7 0.0 8.1 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.6 EKX34542.1 - 1.5e-05 25.3 5.9 0.11 12.9 0.1 4.3 5 0 0 5 5 5 2 HEAT repeats Cnd1 PF12717.7 EKX34542.1 - 0.00013 22.1 6.3 0.0086 16.1 0.2 3.6 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EKX34542.1 - 0.0025 16.4 4.9 0.013 14.1 0.0 3.0 3 0 0 3 3 3 1 Adaptin N terminal region Cohesin_HEAT PF12765.7 EKX34542.1 - 0.096 13.0 0.5 0.56 10.6 0.0 2.7 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion FliH PF02108.16 EKX34542.1 - 5.6 7.0 7.3 3.6 7.7 2.4 2.7 3 0 0 3 3 3 0 Flagellar assembly protein FliH Casc1_N PF15927.5 EKX34543.1 - 6.6e-15 55.3 22.3 4.6e-14 52.6 18.8 2.7 1 1 0 1 1 1 1 Cancer susceptibility candidate 1 N-terminus Complex1_49kDa PF00346.19 EKX34543.1 - 0.088 11.9 5.7 0.092 11.8 0.2 2.4 3 0 0 3 3 3 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit FlxA PF14282.6 EKX34543.1 - 2 8.4 5.9 1.8 8.6 3.6 2.1 1 1 0 1 1 1 0 FlxA-like protein Mpp10 PF04006.12 EKX34544.1 - 0.00052 18.6 16.7 0.00077 18.0 16.7 1.2 1 0 0 1 1 1 1 Mpp10 protein Nop14 PF04147.12 EKX34544.1 - 0.001 17.4 13.4 0.0013 17.0 13.4 1.2 1 0 0 1 1 1 1 Nop14-like family Paf1 PF03985.13 EKX34544.1 - 0.0012 18.0 21.0 0.0017 17.4 21.0 1.3 1 0 0 1 1 1 1 Paf1 DUF5523 PF17661.1 EKX34544.1 - 0.0021 17.8 19.2 0.0034 17.1 19.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5523) DDHD PF02862.17 EKX34544.1 - 0.0022 18.2 1.4 0.0035 17.5 1.4 1.4 1 0 0 1 1 1 1 DDHD domain SpoIIP PF07454.11 EKX34544.1 - 0.0023 17.5 7.1 0.0036 16.8 7.1 1.3 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) SDA1 PF05285.12 EKX34544.1 - 0.0024 17.4 14.3 0.0035 16.8 14.3 1.3 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 EKX34544.1 - 0.003 15.9 14.4 0.003 15.9 14.4 1.4 2 0 0 2 2 2 1 CDC45-like protein RNA_pol_3_Rpc31 PF11705.8 EKX34544.1 - 0.0035 17.6 13.0 0.0063 16.8 13.0 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 EKX34544.1 - 0.0058 16.0 11.2 0.0077 15.6 11.2 1.3 1 0 0 1 1 1 1 BUD22 Presenilin PF01080.17 EKX34544.1 - 0.013 14.3 8.0 0.02 13.7 8.0 1.4 1 0 0 1 1 1 0 Presenilin RRN3 PF05327.11 EKX34544.1 - 0.013 14.0 10.3 0.018 13.6 10.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4820 PF16091.5 EKX34544.1 - 0.019 14.3 7.7 0.038 13.4 7.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CPSF100_C PF13299.6 EKX34544.1 - 0.027 14.6 7.9 0.05 13.8 7.9 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PTPRCAP PF15713.5 EKX34544.1 - 0.033 14.5 18.5 0.061 13.6 18.5 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF2052 PF09747.9 EKX34544.1 - 0.035 14.2 20.1 0.07 13.2 20.1 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Tim54 PF11711.8 EKX34544.1 - 0.037 12.8 10.1 0.065 12.0 10.1 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF913 PF06025.12 EKX34544.1 - 0.05 12.6 9.6 0.031 13.3 7.6 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Plasmodium_Vir PF05795.11 EKX34544.1 - 0.063 12.7 4.3 0.094 12.1 4.3 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein NPR3 PF03666.13 EKX34544.1 - 0.079 11.7 5.7 0.12 11.1 5.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF5308 PF17233.2 EKX34544.1 - 0.14 12.4 5.9 0.12 12.6 3.9 2.0 2 0 0 2 2 1 0 Family of unknown function (DUF5308) CobT PF06213.12 EKX34544.1 - 0.16 11.3 26.6 0.35 10.2 26.6 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Astro_capsid_p PF12226.8 EKX34544.1 - 0.19 10.9 10.2 0.28 10.3 10.2 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RNA_polI_A34 PF08208.11 EKX34544.1 - 0.19 11.8 10.0 0.42 10.7 10.0 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF4746 PF15928.5 EKX34544.1 - 0.21 11.0 13.7 0.33 10.3 13.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RPA43_OB PF17875.1 EKX34544.1 - 0.24 12.0 4.7 0.65 10.6 4.7 1.8 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Gti1_Pac2 PF09729.9 EKX34544.1 - 0.33 11.0 3.5 0.79 9.8 3.5 1.7 1 0 0 1 1 1 0 Gti1/Pac2 family Mem_trans PF03547.18 EKX34544.1 - 0.4 9.0 3.4 0.64 8.4 1.7 2.0 2 0 0 2 2 2 0 Membrane transport protein TRAP_alpha PF03896.16 EKX34544.1 - 0.43 9.7 12.2 0.83 8.8 12.2 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF740 PF05340.12 EKX34544.1 - 0.45 9.2 12.2 0.68 8.6 12.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF740) DUF4045 PF13254.6 EKX34544.1 - 0.46 10.1 8.0 0.67 9.5 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Pox_Ag35 PF03286.14 EKX34544.1 - 0.77 9.5 14.7 1.7 8.4 14.7 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Coilin_N PF15862.5 EKX34544.1 - 0.8 9.5 9.8 1.7 8.5 9.8 1.6 1 0 0 1 1 1 0 Coilin N-terminus DNA_pol_phi PF04931.13 EKX34544.1 - 0.96 7.5 24.7 1.5 6.8 24.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_Rpc4 PF05132.14 EKX34544.1 - 0.99 9.8 8.4 2 8.8 8.4 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Tfb4 PF03850.14 EKX34544.1 - 1.2 8.6 4.3 1 8.8 1.6 2.1 2 0 0 2 2 2 0 Transcription factor Tfb4 Roughex PF06020.11 EKX34544.1 - 1.4 7.9 12.4 2.6 7.0 12.4 1.4 1 0 0 1 1 1 0 Drosophila roughex protein DUF4637 PF15470.6 EKX34544.1 - 1.9 8.2 20.3 3.6 7.3 20.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Zip PF02535.22 EKX34544.1 - 2.2 7.4 6.9 3.8 6.7 6.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter GST_C PF00043.25 EKX34544.1 - 2.5 8.4 0.0 2.5 8.4 0.0 2.7 2 1 0 2 2 1 0 Glutathione S-transferase, C-terminal domain Afi1 PF07792.12 EKX34544.1 - 2.8 8.4 12.6 7.1 7.1 12.6 1.6 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking EIIBC-GUT_N PF03612.14 EKX34544.1 - 7.2 6.3 7.6 14 5.3 7.6 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Merozoite_SPAM PF07133.11 EKX34544.1 - 9 6.2 35.0 16 5.4 35.0 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Cytomega_UL84 PF06284.11 EKX34544.1 - 9.6 4.5 7.9 15 3.9 7.9 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein MORN PF02493.20 EKX34545.1 - 1.9e-09 36.8 12.8 8.8e-05 22.2 4.1 4.0 4 1 1 5 5 5 2 MORN repeat LysM PF01476.20 EKX34546.1 - 6.8e-05 22.9 0.3 9.8e-05 22.3 0.3 1.2 1 0 0 1 1 1 1 LysM domain PAN_4 PF14295.6 EKX34547.1 - 3.7e-05 23.5 2.3 8e-05 22.5 2.3 1.5 1 0 0 1 1 1 1 PAN domain C2 PF00168.30 EKX34548.1 - 4.6e-23 81.5 0.0 4.9e-23 81.4 0.0 1.0 1 0 0 1 1 1 1 C2 domain HEAT_2 PF13646.6 EKX34549.1 - 3.6e-22 78.6 14.6 5.8e-12 45.8 1.0 3.0 2 1 1 3 3 3 3 HEAT repeats HEAT PF02985.22 EKX34549.1 - 6.2e-13 47.8 4.7 3.4e-05 23.7 0.1 4.5 4 0 0 4 4 4 3 HEAT repeat Cnd1 PF12717.7 EKX34549.1 - 1.6e-07 31.5 0.1 1.5e-05 25.1 0.1 2.3 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EKX34549.1 - 1.9e-05 25.1 7.1 0.0046 17.4 1.2 3.7 2 1 2 4 4 4 3 HEAT-like repeat HEAT_PBS PF03130.16 EKX34549.1 - 0.00063 20.2 12.1 0.43 11.4 0.8 5.1 5 1 0 5 5 4 1 PBS lyase HEAT-like repeat Adaptin_N PF01602.20 EKX34549.1 - 0.0029 16.2 0.2 0.038 12.6 0.0 2.0 2 0 0 2 2 2 1 Adaptin N terminal region Arm PF00514.23 EKX34549.1 - 0.0044 17.0 0.2 0.71 10.0 0.0 3.7 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat ALF PF03752.13 EKX34549.1 - 0.0064 16.4 2.8 0.051 13.5 0.1 2.8 3 0 0 3 3 3 1 Short repeats of unknown function RTP1_C1 PF10363.9 EKX34549.1 - 0.028 14.6 0.0 0.28 11.4 0.0 2.3 1 1 1 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 API5 PF05918.11 EKX34549.1 - 0.044 12.6 0.2 0.52 9.1 0.1 2.3 2 1 1 3 3 3 0 Apoptosis inhibitory protein 5 (API5) ERAP1_C PF11838.8 EKX34549.1 - 0.05 13.1 0.1 0.064 12.8 0.1 1.2 1 0 0 1 1 1 0 ERAP1-like C-terminal domain CLASP_N PF12348.8 EKX34549.1 - 0.12 11.9 0.1 12 5.3 0.0 2.3 1 1 0 1 1 1 0 CLASP N terminal Cohesin_HEAT PF12765.7 EKX34549.1 - 0.2 12.0 1.6 3.8 7.9 0.0 3.5 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion PDZ PF00595.24 EKX34550.1 - 2.9e-06 27.5 0.7 1.4e-05 25.4 0.1 2.2 2 1 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX34550.1 - 7.1e-06 26.3 0.1 0.00011 22.5 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EKX34550.1 - 2.7e-05 23.9 0.2 0.00046 20.0 0.1 2.2 2 0 0 2 2 2 1 PDZ domain DCAF15_WD40 PF14939.6 EKX34550.1 - 0.085 12.5 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat Herpes_UL95 PF03038.14 EKX34552.1 - 0.059 12.5 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 UL95 family TIP120 PF08623.10 EKX34552.1 - 0.091 12.5 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) C2 PF00168.30 EKX34553.1 - 5.8e-10 39.4 0.4 0.00033 20.9 0.3 5.6 3 2 0 3 3 3 2 C2 domain WW PF00397.26 EKX34554.1 - 7.2e-13 48.4 0.6 1.1e-12 47.8 0.6 1.3 1 0 0 1 1 1 1 WW domain DUF2015 PF09435.10 EKX34555.1 - 0.098 12.5 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2015) ThiF PF00899.21 EKX34556.1 - 1.4e-114 381.6 0.0 6.4e-72 241.8 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EKX34556.1 - 3e-94 315.6 0.1 3e-94 315.6 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 EKX34556.1 - 1.2e-34 118.4 0.3 6.2e-34 116.0 0.2 2.2 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 EKX34556.1 - 2.1e-31 108.4 0.2 5.3e-31 107.2 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 EKX34556.1 - 3.5e-21 75.2 0.9 1.9e-20 72.8 0.3 2.6 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle PEPCK_ATP PF01293.20 EKX34557.1 - 4.8e-192 638.8 0.0 6.1e-192 638.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase Pyr_redox_2 PF07992.14 EKX34558.1 - 1.1e-46 159.4 0.0 1.3e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EKX34558.1 - 2e-10 41.1 0.0 6.5e-10 39.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EKX34558.1 - 0.065 12.8 0.6 0.36 10.4 0.7 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase RRM_1 PF00076.22 EKX34559.1 - 3.4e-16 58.8 0.0 5.6e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Flavin_Reduct PF01613.18 EKX34561.1 - 9.5e-23 81.0 0.1 1.3e-22 80.5 0.1 1.1 1 0 0 1 1 1 1 Flavin reductase like domain tRNA-synt_2 PF00152.20 EKX34562.1 - 3.3e-66 223.5 0.0 1.1e-39 136.4 0.0 2.2 1 1 1 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EKX34562.1 - 4.4e-12 45.8 0.1 8.6e-12 44.9 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain WHEP-TRS PF00458.20 EKX34562.1 - 6.5e-10 39.0 7.3 1.6e-09 37.8 7.3 1.7 1 0 0 1 1 1 1 WHEP-TRS domain SH3-RhoG_link PF16609.5 EKX34562.1 - 0.0064 16.3 0.7 0.012 15.4 0.7 1.5 1 0 0 1 1 1 1 SH3-RhoGEF linking unstructured region tRNA-synt_2 PF00152.20 EKX34563.1 - 1.7e-62 211.4 0.1 7.9e-33 113.9 0.0 2.7 1 1 1 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EKX34563.1 - 4.7e-13 48.9 0.1 9.6e-13 47.9 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain WHEP-TRS PF00458.20 EKX34563.1 - 3.3e-07 30.3 6.1 8.1e-07 29.1 6.1 1.7 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_2d PF01409.20 EKX34563.1 - 0.21 11.0 0.4 0.85 9.1 0.1 2.1 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) SURF2 PF05477.11 EKX34563.1 - 1.2 8.8 9.2 1.8 8.2 9.2 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) tRNA-synt_2 PF00152.20 EKX34564.1 - 5.3e-81 272.1 0.0 6.5e-81 271.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EKX34564.1 - 1.2e-12 47.6 0.6 3.1e-12 46.3 0.6 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EKX34564.1 - 2.5e-05 23.9 0.3 0.19 11.1 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) DUF4198 PF10670.9 EKX34564.1 - 0.17 12.2 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) Ribosomal_L44 PF00935.19 EKX34565.1 - 1.7e-29 102.1 7.8 1.7e-29 102.1 7.8 1.5 2 0 0 2 2 2 1 Ribosomal protein L44 Eapp_C PF10238.9 EKX34565.1 - 0.44 10.6 7.5 0.2 11.7 3.4 1.9 1 1 1 2 2 2 0 E2F-associated phosphoprotein zinc_ribbon_12 PF11331.8 EKX34565.1 - 8.5 6.3 8.0 0.7 9.7 1.6 2.2 2 0 0 2 2 2 0 Probable zinc-ribbon domain Ribosomal_L44 PF00935.19 EKX34566.1 - 8e-30 103.1 7.8 9.3e-30 102.9 7.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L44 EamA PF00892.20 EKX34567.1 - 1.1e-09 38.5 18.7 1.8e-06 28.2 9.4 2.3 2 0 0 2 2 2 2 EamA-like transporter family DUF3040 PF11239.8 EKX34569.1 - 1.2 9.4 4.1 12 6.3 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) O-antigen_lig PF13425.6 EKX34570.1 - 0.48 9.2 2.8 0.71 8.6 2.8 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein SID-1_RNA_chan PF13965.6 EKX34570.1 - 0.88 7.9 1.9 1 7.7 1.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.16 EKX34570.1 - 3.2 7.8 5.1 4.6 7.2 5.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SID-1_RNA_chan PF13965.6 EKX34571.1 - 0.047 12.1 0.1 0.058 11.8 0.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 VIR_N PF15912.5 EKX34571.1 - 0.42 10.2 14.7 0.54 9.8 14.7 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Mpp10 PF04006.12 EKX34571.1 - 0.43 9.0 37.5 0.64 8.4 37.5 1.3 1 0 0 1 1 1 0 Mpp10 protein Serinc PF03348.15 EKX34571.1 - 0.58 9.0 3.7 0.9 8.4 3.7 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) PPL5 PF18168.1 EKX34571.1 - 0.7 9.1 12.0 0.99 8.6 12.0 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Presenilin PF01080.17 EKX34571.1 - 1 8.1 12.7 1.4 7.6 12.7 1.1 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 EKX34571.1 - 1.4 7.0 47.1 2 6.5 47.1 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EKX34571.1 - 2.1 7.7 49.5 2.9 7.2 49.5 1.1 1 0 0 1 1 1 0 SDA1 DUF4820 PF16091.5 EKX34571.1 - 2.5 7.4 16.1 4.2 6.7 16.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) SAPS PF04499.15 EKX34571.1 - 2.9 6.6 19.4 3.7 6.2 19.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 EKX34571.1 - 4.5 6.1 11.7 7.1 5.5 11.7 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SpoIIIAH PF12685.7 EKX34571.1 - 4.9 6.9 21.0 7.6 6.3 21.0 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein TbpB_A PF17484.2 EKX34572.1 - 0.02 15.7 2.2 0.11 13.3 1.3 2.3 1 1 1 2 2 2 0 N-Lobe handle Tf-binding protein B Uteroglobin PF01099.17 EKX34576.1 - 8 6.9 7.1 55 4.2 7.1 2.2 1 1 0 1 1 1 0 Uteroglobin family Chromate_transp PF02417.15 EKX34579.1 - 3.7e-59 199.4 35.7 7.2e-34 117.2 9.8 2.5 3 0 0 3 3 3 2 Chromate transporter 7TM_GPCR_Sru PF10322.9 EKX34579.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru Ribosomal_L36e PF01158.18 EKX34580.1 - 2.4e-35 120.7 8.1 2.7e-35 120.5 8.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DUF2617 PF10936.8 EKX34581.1 - 0.055 13.5 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF2617 GBP PF02263.19 EKX34581.1 - 0.056 12.7 0.0 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain NB-ARC PF00931.22 EKX34581.1 - 0.089 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Radial_spoke PF04712.12 EKX34581.1 - 0.099 11.6 0.2 0.13 11.2 0.2 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein AAA_30 PF13604.6 EKX34581.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain IF4E PF01652.18 EKX34582.1 - 4.3e-09 36.4 0.3 6.1e-09 35.9 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E SR-25 PF10500.9 EKX34582.1 - 1.3 8.6 7.1 1.9 8.1 7.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Zip PF02535.22 EKX34583.1 - 3.8e-08 33.0 22.4 6.8e-08 32.1 10.6 2.4 1 1 0 2 2 2 2 ZIP Zinc transporter Beta_propel PF09826.9 EKX34584.1 - 0.12 11.1 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Beta propeller domain DUF938 PF06080.12 EKX34585.1 - 1.6e-59 201.1 0.0 1.9e-59 200.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_25 PF13649.6 EKX34585.1 - 1.1e-09 38.8 0.0 1.9e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX34585.1 - 2.1e-06 28.3 0.0 3.5e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX34585.1 - 1.1e-05 25.3 0.0 1.4e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX34585.1 - 4.4e-05 24.2 0.0 7.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EKX34585.1 - 0.002 17.6 0.0 0.008 15.7 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 EKX34585.1 - 0.0043 16.6 0.0 0.19 11.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain TRM PF02005.16 EKX34585.1 - 0.11 11.6 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Myb_DNA-binding PF00249.31 EKX34586.1 - 7.9e-08 32.4 2.9 1.5e-07 31.5 0.1 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.17 EKX34586.1 - 9.1e-05 22.2 1.4 0.0002 21.1 1.4 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.6 EKX34586.1 - 0.00088 19.5 0.0 0.0036 17.5 0.0 2.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF5327 PF17261.2 EKX34586.1 - 3.4 8.5 8.3 0.94 10.3 4.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5327) DAGK_cat PF00781.24 EKX34588.1 - 2.2e-27 95.2 0.0 3.6e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Sec1 PF00995.23 EKX34589.1 - 8.6e-90 302.6 0.0 3.7e-89 300.5 0.0 1.7 1 1 0 1 1 1 1 Sec1 family LEA_6 PF10714.9 EKX34589.1 - 0.14 12.2 0.1 1.4 9.0 0.0 2.6 3 0 0 3 3 3 0 Late embryogenesis abundant protein 18 Glyco_transf_8 PF01501.20 EKX34590.1 - 0.00028 20.5 0.2 0.0012 18.5 0.2 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 PMG PF05287.12 EKX34593.1 - 0.0051 16.9 21.7 0.069 13.2 8.9 2.1 1 1 1 2 2 2 2 PMG protein GCP_C_terminal PF04130.13 EKX34593.1 - 2.8 7.3 3.7 1.4e+02 1.7 0.1 3.9 1 1 2 4 4 4 0 Gamma tubulin complex component C-terminal CHCH PF06747.13 EKX34594.1 - 0.059 13.5 0.1 21 5.4 0.0 2.7 3 0 0 3 3 3 0 CHCH domain Glyco_transf_8 PF01501.20 EKX34595.1 - 0.00028 20.5 0.2 0.0012 18.5 0.2 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 PseudoU_synth_1 PF01416.20 EKX34596.1 - 1.2e-10 41.8 0.0 6.2e-08 33.1 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase LRR_6 PF13516.6 EKX34596.1 - 0.11 12.7 0.8 0.3 11.3 0.0 2.2 2 0 0 2 2 2 0 Leucine Rich repeat Neur_chan_memb PF02932.16 EKX34597.1 - 0.21 11.6 4.1 0.23 11.5 4.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MRP-L46 PF11788.8 EKX34597.1 - 0.24 12.2 6.7 0.38 11.5 6.7 1.3 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 DUF4746 PF15928.5 EKX34597.1 - 0.57 9.6 11.1 0.8 9.1 11.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RR_TM4-6 PF06459.12 EKX34597.1 - 0.79 9.5 14.7 1 9.1 14.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Borrelia_P83 PF05262.11 EKX34597.1 - 1.1 7.7 25.5 1.4 7.3 25.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein TERB2 PF15101.6 EKX34597.1 - 1.9 8.5 8.3 2.6 8.0 8.3 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF2052 PF09747.9 EKX34597.1 - 2.8 8.0 12.6 3.6 7.7 12.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DDHD PF02862.17 EKX34597.1 - 3.6 7.7 5.6 4.4 7.4 5.6 1.2 1 0 0 1 1 1 0 DDHD domain XRN_M PF17846.1 EKX34597.1 - 9.1 5.1 11.0 11 4.8 11.0 1.1 1 0 0 1 1 1 0 Xrn1 helical domain DUF1757 PF08560.10 EKX34598.1 - 7e-05 22.9 0.1 9e-05 22.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) Ank_5 PF13857.6 EKX34599.1 - 0.015 15.6 0.1 0.51 10.7 0.0 3.5 4 0 0 4 4 4 0 Ankyrin repeats (many copies) MORN PF02493.20 EKX34599.1 - 0.034 14.0 1.1 0.034 14.0 1.1 1.9 2 0 0 2 2 2 0 MORN repeat IQ PF00612.27 EKX34599.1 - 0.056 13.3 0.6 0.12 12.2 0.6 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif Ank_2 PF12796.7 EKX34599.1 - 0.077 13.6 0.0 0.42 11.2 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX34599.1 - 0.1 13.2 0.1 7.2 7.5 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat MORN PF02493.20 EKX34600.1 - 9.9e-05 22.0 3.7 0.0092 15.8 1.1 3.6 3 0 0 3 3 3 2 MORN repeat Phycobilisome PF00502.19 EKX34601.1 - 0.011 15.6 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 Phycobilisome protein GIT_CC PF16559.5 EKX34602.1 - 0.12 12.3 0.2 0.34 10.8 0.2 1.8 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor LRR_8 PF13855.6 EKX34603.1 - 2e-24 85.1 12.9 2.4e-15 56.0 6.3 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EKX34603.1 - 1.4e-10 41.3 12.5 3.1e-06 27.4 1.3 3.5 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX34603.1 - 1.6e-09 37.8 0.0 2.7e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EKX34603.1 - 0.0052 17.2 11.0 0.21 12.3 0.4 5.0 4 1 0 4 4 4 1 Leucine Rich Repeat LRR_9 PF14580.6 EKX34603.1 - 0.041 13.4 0.8 0.28 10.7 0.3 2.0 1 1 1 2 2 2 0 Leucine-rich repeat DUF2968 PF11180.8 EKX34604.1 - 0.014 15.0 0.2 0.024 14.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) WD40 PF00400.32 EKX34605.1 - 4.3e-05 24.2 1.8 0.22 12.5 0.1 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX34605.1 - 0.011 16.1 0.0 4 7.8 0.0 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain CH PF00307.31 EKX34607.1 - 0.044 14.0 0.1 0.88 9.8 0.0 2.7 3 0 0 3 3 3 0 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EKX34607.1 - 0.15 11.9 0.0 0.47 10.3 0.0 1.8 1 0 0 1 1 1 0 CAMSAP CH domain DeoC PF01791.9 EKX34608.1 - 1.7e-14 54.0 0.0 2.4e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 DeoC/LacD family aldolase Imm71 PF15602.6 EKX34608.1 - 0.19 11.8 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 71 Methyltransf_3 PF01596.17 EKX34610.1 - 3.3e-18 65.7 0.0 3.9e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EKX34610.1 - 9.7e-11 42.6 0.0 1.3e-10 42.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 EKX34610.1 - 0.0076 15.9 0.0 0.01 15.5 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit TPR_2 PF07719.17 EKX34611.1 - 1.7e-07 30.8 4.6 0.011 15.8 0.3 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX34611.1 - 1e-06 29.3 7.3 3.3e-06 27.6 7.3 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX34611.1 - 0.00051 20.2 0.5 0.0011 19.1 0.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EKX34611.1 - 0.00066 19.8 3.5 0.0015 18.7 3.5 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX34611.1 - 0.00071 20.0 1.9 0.00071 20.0 1.9 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX34611.1 - 0.0051 16.6 1.8 0.26 11.2 0.6 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat SET PF00856.28 EKX34611.1 - 0.0079 16.6 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 SET domain TPR_14 PF13428.6 EKX34611.1 - 0.013 16.2 0.5 0.013 16.2 0.5 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EKX34611.1 - 0.071 12.8 1.1 0.14 11.9 1.1 1.5 1 0 0 1 1 1 0 TPR repeat TPR_12 PF13424.6 EKX34611.1 - 0.62 10.4 4.5 2.3 8.6 4.5 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Mito_carr PF00153.27 EKX34618.1 - 0.022 14.7 0.9 1.9 8.5 0.1 2.7 2 1 1 3 3 3 0 Mitochondrial carrier protein His_Phos_1 PF00300.22 EKX34619.1 - 1.9e-26 93.0 0.0 2.5e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) TPR_12 PF13424.6 EKX34622.1 - 1.3e-27 95.9 0.7 6.8e-16 58.3 0.1 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX34622.1 - 2.3e-20 71.8 5.5 7.7e-07 28.8 0.1 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 EKX34622.1 - 4.1e-17 61.2 7.3 1.6e-06 27.7 0.8 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX34622.1 - 6e-17 60.3 5.7 1.4e-05 24.8 0.5 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX34622.1 - 8.3e-13 47.4 3.8 3.8e-05 23.4 0.1 3.6 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX34622.1 - 3.8e-10 39.2 5.7 0.00092 19.3 0.5 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX34622.1 - 2.4e-07 30.4 0.3 3.2e-07 30.1 0.3 1.2 1 0 0 1 1 1 1 MalT-like TPR region TPR_11 PF13414.6 EKX34622.1 - 2.6e-07 30.2 8.6 0.0028 17.3 1.4 3.9 4 1 1 5 5 5 2 TPR repeat TPR_6 PF13174.6 EKX34622.1 - 6.1e-07 29.7 2.3 0.051 14.2 0.3 3.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX34622.1 - 1.2e-06 28.9 1.1 0.072 13.9 0.1 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX34622.1 - 1.2e-05 25.9 2.9 0.27 11.9 0.1 3.3 4 0 0 4 4 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX34622.1 - 0.00037 20.6 3.9 0.5 10.6 0.3 3.3 1 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 EKX34622.1 - 0.003 17.6 2.6 0.22 11.6 0.0 3.0 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 EKX34622.1 - 0.0057 17.1 2.9 0.091 13.3 0.4 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat SPO22 PF08631.10 EKX34622.1 - 0.008 15.7 0.3 0.02 14.4 0.3 1.7 1 1 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like MIT PF04212.18 EKX34622.1 - 0.016 15.2 2.9 0.33 11.1 0.0 3.2 2 1 2 4 4 3 0 MIT (microtubule interacting and transport) domain Sel1 PF08238.12 EKX34622.1 - 0.022 15.5 0.6 6.9 7.5 0.1 3.1 3 0 0 3 3 3 0 Sel1 repeat DUF5113 PF17140.4 EKX34622.1 - 0.031 14.1 2.5 0.21 11.4 0.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF5113) SHNi-TPR PF10516.9 EKX34622.1 - 0.046 13.2 0.2 1 8.8 0.0 2.6 2 0 0 2 2 2 0 SHNi-TPR TPR_9 PF13371.6 EKX34622.1 - 0.052 13.7 1.0 26 5.0 0.1 3.1 1 1 1 3 3 3 0 Tetratricopeptide repeat DUF4404 PF14357.6 EKX34622.1 - 0.064 13.9 0.1 2.4 8.9 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) Peptidase_M13_N PF05649.13 EKX34624.1 - 1.6e-77 261.8 1.2 3.3e-77 260.8 0.2 1.8 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13 PF01431.21 EKX34624.1 - 1.6e-55 187.9 0.2 3.7e-55 186.7 0.2 1.7 1 1 0 1 1 1 1 Peptidase family M13 TrmO PF01980.16 EKX34625.1 - 6.8e-37 126.3 0.0 8.2e-37 126.1 0.0 1.1 1 0 0 1 1 1 1 tRNA-methyltransferase O Adap_comp_sub PF00928.21 EKX34627.1 - 1.7e-50 171.9 0.0 2.2e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EKX34627.1 - 0.073 13.0 0.2 0.14 12.1 0.2 1.4 1 0 0 1 1 1 0 Clathrin adaptor complex small chain Peptidase_S41 PF03572.18 EKX34629.1 - 0.024 14.2 0.0 0.097 12.2 0.0 1.8 1 1 1 2 2 2 0 Peptidase family S41 DUF4340 PF14238.6 EKX34631.1 - 0.024 14.7 0.6 0.043 13.9 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4340) UQ_con PF00179.26 EKX34632.1 - 5e-48 162.3 0.0 5.7e-48 162.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EKX34632.1 - 0.002 17.8 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EKX34632.1 - 0.015 15.5 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 0 RWD domain Chorismate_bind PF00425.18 EKX34633.1 - 2.5e-65 220.6 0.0 3.3e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 EKX34633.1 - 1.8e-36 125.7 0.0 2.7e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EKX34633.1 - 3.8e-11 43.1 0.1 1e-10 41.7 0.1 1.7 1 1 0 1 1 1 1 Peptidase C26 Anth_synt_I_N PF04715.13 EKX34633.1 - 3.3e-05 24.1 0.0 0.00092 19.4 0.0 3.0 3 1 0 3 3 3 1 Anthranilate synthase component I, N terminal region MoCF_biosynth PF00994.24 EKX34633.1 - 0.14 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Probable molybdopterin binding domain Glycos_transf_3 PF00591.21 EKX34634.1 - 4.4e-87 291.9 1.5 5.7e-87 291.5 0.6 1.5 2 0 0 2 2 2 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EKX34634.1 - 1.7e-13 50.2 1.9 2.3e-12 46.6 0.1 2.5 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain DUF5009 PF16401.5 EKX34635.1 - 0.077 12.5 0.6 0.14 11.6 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5009) Yae1_N PF09811.9 EKX34635.1 - 0.32 10.7 25.7 0.66 9.7 0.6 6.3 6 1 1 7 7 7 0 Essential protein Yae1, N terminal CD20 PF04103.15 EKX34635.1 - 0.99 9.5 29.5 7.1 6.7 18.0 3.9 2 1 1 3 3 3 0 CD20-like family Tetraspanin PF00335.20 EKX34635.1 - 5.1 6.7 14.5 3.8 7.2 0.4 3.2 3 1 0 3 3 3 0 Tetraspanin family DUF1622 PF07784.11 EKX34636.1 - 0.022 14.6 1.2 0.07 13.0 1.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1622) ANAPC4_WD40 PF12894.7 EKX34637.1 - 4e-07 30.2 0.1 0.0019 18.5 0.0 3.4 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EKX34637.1 - 8.9e-06 26.4 0.0 0.01 16.7 0.0 3.7 3 1 1 4 4 4 1 WD domain, G-beta repeat DUF870 PF05912.11 EKX34637.1 - 0.027 14.5 0.0 0.076 13.0 0.0 1.8 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF870) Frtz PF11768.8 EKX34637.1 - 0.093 11.0 0.1 1 7.6 0.0 2.0 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz CENP-X PF09415.10 EKX34637.1 - 2.3 8.6 5.6 4.4 7.7 0.4 3.2 3 0 0 3 3 3 0 CENP-S associating Centromere protein X HAUS6_N PF14661.6 EKX34639.1 - 3.5e-29 102.0 3.3 1.2e-28 100.3 0.5 2.1 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus DUF4081 PF13312.6 EKX34639.1 - 0.13 12.4 0.5 1.4 9.1 0.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4081) RPW8 PF05659.11 EKX34639.1 - 0.22 11.2 2.7 5.9 6.6 0.1 3.0 4 0 0 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 THOC7 PF05615.13 EKX34639.1 - 2.1 8.6 10.7 25 5.2 2.5 3.3 2 1 1 3 3 3 0 Tho complex subunit 7 DUF1296 PF06972.11 EKX34640.1 - 0.059 13.5 0.2 0.14 12.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) Hydin_ADK PF17213.3 EKX34640.1 - 0.29 11.4 8.0 0.19 12.0 0.2 2.7 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Methyltrn_RNA_3 PF02598.17 EKX34641.1 - 0.11 12.0 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Putative RNA methyltransferase BTK PF00779.19 EKX34641.1 - 0.2 11.5 4.2 0.4 10.5 4.2 1.5 1 0 0 1 1 1 0 BTK motif Hydrolase_4 PF12146.8 EKX34642.1 - 2.2e-21 76.2 0.0 1.6e-19 70.1 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EKX34642.1 - 1.7e-15 58.2 0.5 2.3e-15 57.8 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EKX34642.1 - 1.7e-12 47.5 0.2 4.4e-08 33.1 0.1 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EKX34642.1 - 1.5e-09 37.6 0.0 2.2e-05 24.0 0.0 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.13 EKX34642.1 - 1.1e-05 25.2 0.0 8.9e-05 22.2 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 EKX34642.1 - 0.075 12.9 0.1 0.24 11.2 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.11 EKX34642.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal LisH PF08513.11 EKX34642.1 - 0.19 11.8 0.5 4.4 7.4 0.0 2.3 2 0 0 2 2 2 0 LisH Palm_thioest PF02089.15 EKX34642.1 - 0.19 11.5 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Pkinase PF00069.25 EKX34643.1 - 6.7e-07 28.9 0.0 1.2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EKX34643.1 - 0.0028 17.0 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Aha1_N PF09229.11 EKX34644.1 - 9.5e-18 64.7 0.0 1.6e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 EKX34644.1 - 4.1e-10 40.0 0.0 8.9e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Vasohibin PF14822.6 EKX34645.1 - 6.6e-55 186.0 0.5 7.5e-55 185.8 0.5 1.0 1 0 0 1 1 1 1 Vasohibin eIF3_N PF09440.10 EKX34646.1 - 1.2e-36 126.1 4.8 1e-35 123.1 4.7 2.3 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 EKX34646.1 - 3.5e-18 66.0 1.1 7.2e-18 65.0 0.3 2.1 2 0 0 2 2 2 1 PCI domain CNRIP1 PF15043.6 EKX34646.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 CB1 cannabinoid receptor-interacting protein 1 ANAPC3 PF12895.7 EKX34646.1 - 0.014 15.6 2.0 2.6 8.4 0.2 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EKX34646.1 - 0.018 15.5 0.5 0.39 11.3 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat SesA PF17107.5 EKX34646.1 - 0.061 13.5 1.9 0.9 9.7 1.7 2.5 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF2683 PF10884.8 EKX34646.1 - 0.26 11.6 1.9 0.34 11.2 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2683) Peptidase_S9 PF00326.21 EKX34647.1 - 1.5e-37 129.1 0.0 2.4e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 EKX34647.1 - 7.6e-06 25.6 0.0 2e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family PD40 PF07676.12 EKX34647.1 - 0.00024 20.9 0.2 0.52 10.3 0.1 3.4 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Hydrolase_4 PF12146.8 EKX34647.1 - 0.0098 15.2 0.1 0.11 11.8 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Gmad1 PF10647.9 EKX34647.1 - 0.022 14.5 0.5 0.07 12.9 0.3 1.9 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain BAAT_C PF08840.11 EKX34647.1 - 0.027 14.4 0.0 6.8 6.5 0.0 2.4 1 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 EKX34647.1 - 0.032 13.8 0.2 0.9 9.1 0.0 2.2 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 EKX34647.1 - 0.094 11.4 0.1 2.4 6.8 0.0 2.4 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) MORN PF02493.20 EKX34648.1 - 3e-15 55.1 32.4 1.2e-05 24.9 1.2 4.7 5 0 0 5 5 5 4 MORN repeat Tudor_2 PF18104.1 EKX34648.1 - 0.0093 15.6 0.4 5.4 6.8 0.1 2.8 2 0 0 2 2 2 2 Jumonji domain-containing protein 2A Tudor domain CLP_protease PF00574.23 EKX34649.1 - 3.2e-57 193.4 0.0 4.2e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Clp protease GST_C_3 PF14497.6 EKX34650.1 - 5.4e-15 55.4 0.4 8e-15 54.8 0.4 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EKX34650.1 - 6.1e-12 45.7 0.0 1.1e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EKX34650.1 - 0.00017 21.7 0.6 0.0019 18.4 0.6 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EKX34650.1 - 0.00046 20.4 0.0 0.00079 19.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EKX34650.1 - 0.0022 18.4 0.0 0.0044 17.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EKX34650.1 - 0.032 14.3 0.1 0.084 12.9 0.1 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Spermine_synth PF01564.17 EKX34650.1 - 0.14 11.6 0.1 0.29 10.5 0.1 1.5 1 1 0 1 1 1 0 Spermine/spermidine synthase domain MIP PF00230.20 EKX34651.1 - 3.9e-34 118.3 10.1 5.1e-34 118.0 10.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein Peptidase_S28 PF05577.12 EKX34652.1 - 1e-105 354.0 0.0 1.2e-105 353.8 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 EKX34652.1 - 9e-06 25.5 0.2 3.6e-05 23.5 0.1 2.0 3 0 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EKX34652.1 - 3.3e-05 23.4 0.0 6.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family MSP1b PF03429.13 EKX34652.1 - 0.11 10.6 0.0 0.16 10.1 0.0 1.1 1 0 0 1 1 1 0 Major surface protein 1B DEAD PF00270.29 EKX34656.1 - 8.2e-30 103.9 0.0 2.7e-29 102.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX34656.1 - 1.5e-11 44.6 0.0 1.1e-09 38.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX34656.1 - 0.00069 19.7 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EKX34656.1 - 0.19 10.4 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Globin PF00042.22 EKX34657.1 - 0.026 15.1 2.6 0.047 14.2 0.8 2.4 2 0 0 2 2 2 0 Globin DUF1358 PF07096.11 EKX34657.1 - 0.18 11.8 1.5 0.74 9.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1358) FAA_hydrolase_N PF09298.11 EKX34657.1 - 0.19 11.9 1.4 5.5 7.2 0.0 3.1 3 1 0 3 3 3 0 Fumarylacetoacetase N-terminal MHB PF16525.5 EKX34657.1 - 0.32 11.3 4.0 3.6 7.9 0.0 4.1 2 1 3 5 5 5 0 Haemophore, haem-binding YcbB PF08664.10 EKX34657.1 - 0.46 10.5 3.8 0.22 11.6 0.4 2.2 2 1 0 2 2 2 0 YcbB domain FAD-SLDH PF12318.8 EKX34657.1 - 4.4 7.4 8.2 35 4.4 0.1 3.6 4 0 0 4 4 4 0 Membrane bound FAD containing D-sorbitol dehydrogenase Myosin_head PF00063.21 EKX34658.1 - 4.6e-229 762.1 0.0 5.3e-229 761.9 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 EKX34658.1 - 0.0026 18.2 0.0 0.14 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EKX34658.1 - 0.0063 16.8 0.1 0.22 11.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 EKX34658.1 - 0.032 14.0 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EKX34658.1 - 0.039 13.9 0.3 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 NACHT domain SLATT_2 PF18183.1 EKX34658.1 - 0.046 13.5 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 2 Hpr_kinase_C PF07475.12 EKX34658.1 - 0.057 12.9 0.0 3.2 7.2 0.0 2.2 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain TsaE PF02367.17 EKX34658.1 - 0.092 12.8 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE GSH-S_N PF02951.14 EKX34659.1 - 0.042 14.0 0.0 0.092 12.9 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain Thioredoxin PF00085.20 EKX34660.1 - 1.3e-58 195.4 0.1 2.7e-30 104.4 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EKX34660.1 - 3.7e-27 95.4 0.6 7.6e-20 71.6 1.4 3.4 2 1 1 3 3 3 3 Thioredoxin-like domain OST3_OST6 PF04756.13 EKX34660.1 - 3.7e-11 42.9 0.1 2.1e-05 24.0 0.0 3.1 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EKX34660.1 - 1.4e-09 38.3 0.2 0.0011 19.5 0.0 3.8 2 2 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EKX34660.1 - 4.3e-08 33.2 0.1 0.002 18.3 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.6 EKX34660.1 - 6.6e-07 29.6 0.4 2.4 8.6 0.0 5.0 3 3 3 6 6 6 3 Thioredoxin-like AhpC-TSA PF00578.21 EKX34660.1 - 3.5e-06 26.9 0.3 0.18 11.7 0.0 3.6 2 1 1 3 3 3 2 AhpC/TSA family ERp29_N PF07912.13 EKX34660.1 - 0.0001 22.5 0.2 0.76 9.9 0.0 3.9 3 1 1 4 4 4 2 ERp29, N-terminal domain Redoxin PF08534.10 EKX34660.1 - 0.0016 18.2 0.2 0.32 10.7 0.0 3.2 3 0 0 3 3 3 1 Redoxin Glutaredoxin PF00462.24 EKX34660.1 - 0.011 16.0 0.2 0.73 10.1 0.0 3.1 2 1 0 2 2 2 0 Glutaredoxin SF3b10 PF07189.11 EKX34662.1 - 4.9e-35 119.5 0.3 5.3e-35 119.4 0.3 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) TraG-D_C PF12696.7 EKX34664.1 - 0.72 9.9 4.9 0.2 11.6 0.7 2.2 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG SHIPPO-rpt PF07004.12 EKX34665.1 - 0.012 16.5 45.7 0.7 10.9 0.1 9.6 9 1 0 9 9 9 0 Sperm-tail PG-rich repeat DUF4611 PF15387.6 EKX34665.1 - 0.77 10.0 8.4 2.7 8.3 0.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RRM_1 PF00076.22 EKX34667.1 - 2e-23 82.0 0.0 4.3e-23 80.9 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zinc_ribbon_4 PF13717.6 EKX34667.1 - 7.7e-09 35.3 0.5 1.5e-08 34.4 0.5 1.5 1 0 0 1 1 1 1 zinc-ribbon domain RRM_7 PF16367.5 EKX34667.1 - 0.00036 20.6 0.1 0.0071 16.4 0.0 2.6 2 1 0 2 2 2 1 RNA recognition motif RRM_occluded PF16842.5 EKX34667.1 - 0.00097 18.9 0.0 0.002 17.9 0.0 1.5 1 1 0 1 1 1 1 Occluded RNA-recognition motif zf-CSL PF05207.13 EKX34667.1 - 0.11 12.3 1.4 0.38 10.5 0.8 2.1 2 0 0 2 2 2 0 CSL zinc finger RRM_5 PF13893.6 EKX34667.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.4 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3797 PF12677.7 EKX34667.1 - 0.56 10.1 7.0 1.1 9.2 0.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) zf-C2H2_3 PF13878.6 EKX34667.1 - 2.5 8.0 5.8 13 5.7 0.8 2.4 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO Myb_DNA-binding PF00249.31 EKX34668.1 - 1.7e-35 121.0 4.2 4.5e-17 62.0 0.6 2.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX34668.1 - 5.4e-29 100.2 2.7 2e-19 69.6 0.2 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EKX34668.1 - 8.7e-07 28.8 0.1 0.028 14.3 0.0 2.0 1 1 1 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 EKX34668.1 - 3.9e-06 26.9 1.0 0.00071 19.7 0.0 2.9 1 1 1 2 2 2 2 Rap1 Myb domain SLIDE PF09111.10 EKX34668.1 - 6.8e-06 26.1 0.0 0.0077 16.2 0.0 2.1 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 EKX34668.1 - 0.0038 17.4 0.1 1.2 9.4 0.0 2.1 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 EKX34668.1 - 0.48 10.8 5.8 2.8 8.4 1.3 3.1 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Hamartin PF04388.12 EKX34669.1 - 6.7 5.2 49.2 10 4.6 49.2 1.5 1 0 0 1 1 1 0 Hamartin protein UPF0193 PF05250.11 EKX34671.1 - 1e-25 90.8 2.3 1.3e-25 90.5 2.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) PBP_like PF12727.7 EKX34671.1 - 0.039 13.1 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 PBP superfamily domain MetOD2 PF18548.1 EKX34671.1 - 0.06 13.5 0.4 0.14 12.3 0.4 1.6 1 0 0 1 1 1 0 Metanogen output domain 2 DUF2408 PF10303.9 EKX34671.1 - 0.061 13.9 0.1 0.087 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Toxin_29 PF08116.11 EKX34672.1 - 0.0098 15.9 1.2 0.025 14.6 1.2 1.6 1 0 0 1 1 1 1 PhTx neurotoxin family SAM_1 PF00536.30 EKX34673.1 - 4.1e-07 30.4 0.0 7.6e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TFIIF_alpha PF05793.12 EKX34673.1 - 0.00038 19.2 19.2 0.00038 19.2 19.2 2.1 2 0 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SAM_2 PF07647.17 EKX34673.1 - 0.00066 19.7 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SDA1 PF05285.12 EKX34673.1 - 0.0074 15.8 41.2 0.095 12.1 19.2 2.1 2 0 0 2 2 2 2 SDA1 MDM1 PF15501.6 EKX34673.1 - 0.031 13.4 47.4 0.021 14.0 22.4 2.3 2 0 0 2 2 2 0 Nuclear protein MDM1 DUF2052 PF09747.9 EKX34673.1 - 0.11 12.7 36.1 0.91 9.6 16.4 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) RPOL_N PF14700.6 EKX34673.1 - 0.19 11.1 24.9 0.05 13.0 7.4 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase N-terminal HNOBA PF07701.14 EKX34673.1 - 0.39 10.1 11.7 0.13 11.7 1.3 2.3 2 0 0 2 2 2 0 Heme NO binding associated BSP_II PF05432.11 EKX34673.1 - 0.49 10.0 36.7 2 8.0 16.1 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Nop14 PF04147.12 EKX34673.1 - 0.71 8.0 35.1 0.34 9.1 17.5 2.1 2 0 0 2 2 2 0 Nop14-like family PI3K_1B_p101 PF10486.9 EKX34673.1 - 0.86 7.3 28.5 0.2 9.4 10.5 2.1 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Merozoite_SPAM PF07133.11 EKX34673.1 - 1 9.3 46.2 3 7.8 26.8 2.3 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) RAB3GAP2_C PF14656.6 EKX34673.1 - 2 6.5 13.6 2.6 6.2 0.8 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit C-terminus BUD22 PF09073.10 EKX34673.1 - 2.2 7.5 48.0 1.7 7.9 14.8 2.1 2 0 0 2 2 2 0 BUD22 CDC45 PF02724.14 EKX34673.1 - 2.5 6.3 35.5 0.67 8.2 16.6 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF4471 PF14740.6 EKX34673.1 - 2.5 7.2 16.4 1.6 7.9 5.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) Plasmodium_Vir PF05795.11 EKX34673.1 - 3.4 7.0 25.7 3.3 7.0 12.0 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Lin-8 PF03353.15 EKX34673.1 - 6.1 6.3 36.1 0.49 9.9 17.5 2.2 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist LTV PF04180.14 EKX34673.1 - 6.8 6.3 31.0 2.4 7.8 12.1 2.2 2 0 0 2 2 2 0 Low temperature viability protein NARP1 PF12569.8 EKX34673.1 - 7.6 5.3 26.5 1.4 7.7 10.8 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 VIR_N PF15912.5 EKX34673.1 - 8.3 5.9 22.4 1.7 8.2 0.7 2.4 2 0 0 2 2 2 0 Virilizer, N-terminal Fuseless PF15993.5 EKX34675.1 - 0.0035 16.6 4.7 0.011 14.9 1.0 2.1 2 0 0 2 2 2 2 Fuseless PRA1 PF03208.19 EKX34675.1 - 0.92 9.1 11.9 0.42 10.2 2.2 2.1 2 0 0 2 2 2 0 PRA1 family protein DUF2721 PF11026.8 EKX34675.1 - 1.7 8.5 0.0 1.7 8.5 0.0 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF2721) PAC1 PF16094.5 EKX34676.1 - 0.085 12.0 1.2 0.14 11.3 1.2 1.2 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 TERB2 PF15101.6 EKX34676.1 - 0.69 9.9 2.8 1 9.4 2.8 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 TFIIA PF03153.13 EKX34676.1 - 0.82 9.6 9.7 0.99 9.3 9.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPT16 PF08644.11 EKX34676.1 - 1.4 9.0 5.4 98 3.1 0.0 2.4 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) Presenilin PF01080.17 EKX34676.1 - 3 6.5 3.3 3.9 6.1 3.3 1.1 1 0 0 1 1 1 0 Presenilin PBP_sp32 PF07222.12 EKX34676.1 - 4.3 6.7 7.9 6.4 6.1 7.9 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Ion_trans PF00520.31 EKX34677.1 - 1.5e-35 122.6 29.4 2.1e-35 122.1 29.4 1.2 1 0 0 1 1 1 1 Ion transport protein PH PF00169.29 EKX34677.1 - 1.2e-06 29.0 0.2 6e-06 26.7 0.2 2.2 1 1 0 1 1 1 1 PH domain DUF2339 PF10101.9 EKX34677.1 - 3.6e-06 25.9 26.6 3.6e-06 25.9 26.6 1.9 1 1 1 2 2 2 1 Predicted membrane protein (DUF2339) PKD_channel PF08016.12 EKX34677.1 - 1.7e-05 23.7 20.0 6.7e-05 21.8 8.7 2.4 1 1 1 2 2 2 2 Polycystin cation channel EF-hand_1 PF00036.32 EKX34677.1 - 3.8e-05 22.9 0.1 0.00017 20.9 0.0 2.2 2 0 0 2 2 2 1 EF hand NPV_P10 PF05531.12 EKX34677.1 - 0.0015 19.0 1.0 0.0058 17.1 1.0 2.0 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein EF-hand_7 PF13499.6 EKX34677.1 - 0.0067 16.8 0.4 0.087 13.3 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX34677.1 - 0.0075 16.1 0.0 0.039 13.9 0.0 2.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 EKX34677.1 - 0.017 14.6 0.2 0.046 13.2 0.2 1.7 1 0 0 1 1 1 0 EF hand DUF2205 PF10224.9 EKX34677.1 - 0.039 13.9 2.0 0.21 11.6 2.0 2.3 1 0 0 1 1 1 0 Short coiled-coil protein TSC22 PF01166.18 EKX34677.1 - 0.091 13.1 0.4 0.091 13.1 0.4 2.3 2 0 0 2 2 1 0 TSC-22/dip/bun family PH_13 PF16652.5 EKX34677.1 - 0.1 12.4 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Med3 PF11593.8 EKX34677.1 - 0.13 11.4 32.3 3.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DivIC PF04977.15 EKX34677.1 - 0.23 11.2 4.1 0.37 10.6 0.2 3.1 3 0 0 3 3 3 0 Septum formation initiator GrpE PF01025.19 EKX34677.1 - 0.79 9.4 6.8 0.82 9.3 3.3 2.5 2 0 0 2 2 2 0 GrpE Cytomega_UL84 PF06284.11 EKX34677.1 - 4.1 5.7 5.7 6.8 5.0 5.7 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein O-FucT PF10250.9 EKX34678.1 - 0.028 14.1 0.0 0.11 12.1 0.0 1.8 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Ion_trans PF00520.31 EKX34679.1 - 3.4e-18 65.8 19.0 5.7e-18 65.0 19.0 1.3 1 0 0 1 1 1 1 Ion transport protein PH PF00169.29 EKX34679.1 - 3.4e-09 37.2 0.2 3.8e-08 33.8 0.1 2.7 2 1 0 2 2 2 1 PH domain PKD_channel PF08016.12 EKX34679.1 - 2.6e-06 26.4 2.2 2.6e-06 26.4 2.2 2.2 1 1 1 2 2 2 1 Polycystin cation channel EF-hand_1 PF00036.32 EKX34679.1 - 0.0011 18.3 0.9 0.34 10.6 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX34679.1 - 0.0058 16.5 0.2 0.39 10.8 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain PH_9 PF15410.6 EKX34679.1 - 0.0087 16.4 0.1 0.074 13.4 0.1 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain EF-hand_7 PF13499.6 EKX34679.1 - 0.05 14.1 2.5 0.24 11.9 0.2 3.0 3 0 0 3 3 3 0 EF-hand domain pair DUF2207 PF09972.9 EKX34679.1 - 0.088 11.6 8.8 7.4 5.2 8.8 2.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4192 PF13830.6 EKX34679.1 - 0.27 11.2 1.8 2.7 8.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) TMEM214 PF10151.9 EKX34679.1 - 2.7 6.3 10.0 4.6 5.6 10.0 1.3 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Methyltransf_16 PF10294.9 EKX34680.1 - 7e-15 55.2 0.0 8.5e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EKX34680.1 - 0.00029 20.4 0.0 0.00036 20.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EKX34680.1 - 0.0016 18.3 0.0 0.0019 18.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX34680.1 - 0.11 13.3 0.0 0.18 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EKX34680.1 - 0.21 11.4 0.0 0.33 10.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Chon_Sulph_att PF06566.11 EKX34681.1 - 0.0046 16.9 0.4 0.0097 15.8 0.1 1.6 1 1 1 2 2 2 1 Chondroitin sulphate attachment domain DUF1908 PF08926.11 EKX34681.1 - 0.04 13.0 0.3 0.059 12.5 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) Oxidored_molyb PF00174.19 EKX34682.1 - 1.3e-07 31.4 0.0 2.5e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Methyltransf_25 PF13649.6 EKX34683.1 - 0.00041 21.0 0.1 0.001 19.7 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EKX34683.1 - 0.0096 15.7 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 EKX34683.1 - 0.018 16.0 0.0 0.043 14.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain NodS PF05401.11 EKX34683.1 - 0.044 13.4 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_11 PF08241.12 EKX34683.1 - 0.068 13.8 0.0 0.15 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EKX34683.1 - 0.15 11.9 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ion_trans PF00520.31 EKX34684.1 - 4.5e-18 65.4 23.6 1.5e-17 63.6 23.6 1.9 1 1 0 1 1 1 1 Ion transport protein PH PF00169.29 EKX34684.1 - 4e-07 30.5 0.0 3e-06 27.7 0.0 2.2 1 1 0 1 1 1 1 PH domain EF-hand_1 PF00036.32 EKX34684.1 - 0.00081 18.8 0.0 0.0023 17.3 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 EKX34684.1 - 0.0085 15.5 0.1 0.02 14.4 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EKX34684.1 - 0.036 14.0 0.0 0.36 10.9 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain VirionAssem_T7 PF11653.8 EKX34685.1 - 0.28 11.7 4.8 12 6.4 0.4 2.6 2 0 0 2 2 2 0 Bacteriophage T7 virion assembly protein TPR_2 PF07719.17 EKX34687.1 - 8.9e-08 31.7 1.3 0.011 15.8 0.1 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX34687.1 - 1e-06 28.3 0.4 0.0033 17.2 0.1 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX34687.1 - 0.00022 21.5 1.4 0.00096 19.4 1.4 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX34687.1 - 0.0025 18.1 0.3 0.18 12.2 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX34687.1 - 0.0039 17.3 0.3 0.044 14.0 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX34687.1 - 0.0059 16.7 1.2 0.007 16.5 1.2 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX34687.1 - 0.025 15.2 0.6 6.3 7.5 0.1 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat 2OG-FeII_Oxy_4 PF13661.6 EKX34688.1 - 5.9e-05 23.6 0.0 0.0012 19.4 0.0 2.4 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EKX34688.1 - 0.0023 18.8 0.0 0.29 12.0 0.0 2.7 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily RNA_polI_A34 PF08208.11 EKX34688.1 - 0.46 10.5 0.0 0.46 10.5 0.0 4.2 1 1 3 4 4 4 0 DNA-directed RNA polymerase I subunit RPA34.5 Mlo PF03094.15 EKX34689.1 - 1.4e-07 30.3 20.8 2.8e-05 22.7 1.2 3.4 3 1 0 3 3 3 3 Mlo family GPI2 PF06432.11 EKX34690.1 - 2.1e-66 224.3 13.1 2.8e-66 223.8 13.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF4112 PF13430.6 EKX34690.1 - 0.099 12.9 2.5 2.1 8.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4112) PDZ PF00595.24 EKX34692.1 - 3.4e-08 33.7 0.1 4.8e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX34692.1 - 5.4e-08 33.1 0.1 9.7e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX34692.1 - 2.2e-07 30.6 0.2 3.9e-07 29.8 0.2 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX34692.1 - 0.074 13.0 0.0 0.95 9.5 0.0 2.2 1 1 0 1 1 1 0 Tricorn protease PDZ domain CmcI PF04989.12 EKX34693.1 - 2.7e-42 144.8 0.0 3.6e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_24 PF13578.6 EKX34693.1 - 7.4e-07 30.2 0.1 4.2e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Copine PF07002.16 EKX34696.1 - 1.4e-67 227.4 0.0 1.7e-67 227.1 0.0 1.1 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 EKX34696.1 - 3.6e-10 40.3 0.0 7.5e-10 39.2 0.0 1.5 1 1 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 EKX34696.1 - 0.00011 22.5 0.0 0.00027 21.2 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain eIF-1a PF01176.19 EKX34698.1 - 1e-15 57.3 0.1 1.5e-15 56.7 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RPA_interact_N PF14766.6 EKX34700.1 - 8.3e-05 22.1 4.6 0.00017 21.1 4.6 1.5 1 0 0 1 1 1 1 Replication protein A interacting N-terminal Spore_YpjB PF09577.10 EKX34700.1 - 0.0068 16.2 0.1 0.013 15.4 0.1 1.4 1 1 0 1 1 1 1 Sporulation protein YpjB (SpoYpjB) GP24_25 PF17388.2 EKX34700.1 - 0.041 13.9 0.3 0.076 13.0 0.2 1.5 1 1 0 1 1 1 0 Tail assembly gene products 24 & 25 SecA_SW PF07516.13 EKX34700.1 - 0.042 13.9 2.8 0.062 13.3 2.8 1.2 1 0 0 1 1 1 0 SecA Wing and Scaffold domain KxDL PF10241.9 EKX34700.1 - 0.14 12.5 1.8 0.29 11.4 1.2 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein DUF572 PF04502.13 EKX34700.1 - 0.8 9.3 4.9 1.2 8.7 4.9 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF572) DUF4208 PF13907.6 EKX34702.1 - 0.099 13.1 0.4 0.24 11.9 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) FAA_hydrolase_N PF09298.11 EKX34703.1 - 0.078 13.2 0.4 7.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal CMAS PF02353.20 EKX34704.1 - 1.5e-57 195.0 0.2 2.1e-57 194.5 0.2 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EKX34704.1 - 4.8e-08 33.6 0.0 9e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX34704.1 - 1.3e-07 32.1 0.0 2.7e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX34704.1 - 7.6e-06 25.9 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX34704.1 - 0.01 15.6 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EKX34704.1 - 0.011 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 EKX34704.1 - 0.033 14.9 0.0 0.082 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 EKX34704.1 - 0.052 13.1 0.0 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Histone methylation protein DOT1 MetW PF07021.12 EKX34704.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Mito_carr PF00153.27 EKX34705.1 - 3.9e-47 158.1 1.4 9.7e-18 63.9 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF4364 PF14277.6 EKX34706.1 - 0.00034 20.4 0.0 0.00055 19.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) LRR_8 PF13855.6 EKX34707.1 - 9.4e-22 76.5 42.7 1.9e-07 30.8 3.3 4.5 2 2 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 EKX34707.1 - 4.2e-15 55.6 18.1 6.5e-06 26.4 3.1 4.8 1 1 1 4 4 4 4 Leucine Rich repeats (2 copies) Pkinase PF00069.25 EKX34707.1 - 4.8e-13 49.1 0.0 1.5e-12 47.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX34707.1 - 4.8e-08 32.6 0.0 2.9e-07 30.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX34707.1 - 4.4e-07 29.5 0.1 1.1e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_9 PF14580.6 EKX34707.1 - 3.3e-05 23.5 6.2 0.00048 19.7 2.1 2.8 1 1 1 2 2 2 1 Leucine-rich repeat APH PF01636.23 EKX34707.1 - 0.001 19.0 0.1 0.002 18.1 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family LRR_1 PF00560.33 EKX34707.1 - 0.046 14.3 17.1 6.8 7.7 0.8 6.2 6 1 0 6 6 6 0 Leucine Rich Repeat CREPT PF16566.5 EKX34707.1 - 0.05 13.8 0.3 3 8.0 0.0 2.4 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour RIO1 PF01163.22 EKX34707.1 - 0.18 11.4 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family LRR_6 PF13516.6 EKX34707.1 - 2.2 8.6 12.8 17 5.8 0.9 4.8 4 0 0 4 4 4 0 Leucine Rich repeat Ank_2 PF12796.7 EKX34708.1 - 3.2e-14 53.3 0.3 6.1e-08 33.2 0.5 3.4 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX34708.1 - 6.2e-13 49.0 2.4 5e-07 30.2 0.3 4.8 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX34708.1 - 4.6e-11 41.9 0.2 0.061 13.9 0.1 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EKX34708.1 - 1e-10 41.6 0.2 9.5e-09 35.4 0.0 3.2 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX34708.1 - 2.9e-10 40.1 0.7 0.12 12.8 0.1 5.6 5 1 0 5 5 5 2 Ankyrin repeat DUF765 PF05570.11 EKX34710.1 - 0.25 11.6 2.7 0.86 9.8 2.7 1.9 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF765) DUF4644 PF15486.6 EKX34710.1 - 0.46 10.2 7.2 0.12 12.1 2.8 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4644) Myosin_head PF00063.21 EKX34711.1 - 1.7e-203 677.6 0.0 2.5e-140 468.8 0.0 2.7 2 1 0 2 2 2 2 Myosin head (motor domain) AAA_16 PF13191.6 EKX34711.1 - 0.0016 18.8 5.0 0.0031 17.9 1.4 3.0 2 1 0 2 2 2 1 AAA ATPase domain Hpr_kinase_C PF07475.12 EKX34711.1 - 0.013 15.0 0.2 4.4 6.8 0.0 2.5 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain AAA_18 PF13238.6 EKX34711.1 - 0.037 14.6 0.3 0.29 11.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EKX34711.1 - 0.047 14.0 0.2 0.23 11.7 0.2 2.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EKX34711.1 - 0.1 13.0 0.2 0.24 11.8 0.2 1.6 1 0 0 1 1 1 0 RNA helicase UPF0175 PF03683.13 EKX34711.1 - 0.1 12.3 0.1 0.28 10.9 0.1 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) T2SSE PF00437.20 EKX34711.1 - 0.14 11.2 0.1 0.34 9.9 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_7 PF12775.7 EKX34711.1 - 0.16 11.5 0.0 0.36 10.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 EKX34711.1 - 0.16 12.3 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 EKX34711.1 - 0.18 11.8 0.2 0.39 10.8 0.2 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DEAD PF00270.29 EKX34711.1 - 0.23 11.2 0.0 0.4 10.4 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_30 PF13604.6 EKX34711.1 - 0.26 11.0 2.2 0.17 11.6 0.2 1.6 2 0 0 2 2 2 0 AAA domain BAH PF01426.18 EKX34712.1 - 1.4e-12 47.5 0.2 1.4e-12 47.5 0.2 2.0 2 0 0 2 2 2 1 BAH domain PDZ_6 PF17820.1 EKX34712.1 - 0.017 15.0 0.0 0.044 13.6 0.0 1.8 1 0 0 1 1 1 0 PDZ domain Ephrin_rec_like PF07699.13 EKX34713.1 - 5e-05 23.0 0.4 0.00014 21.5 0.4 1.8 1 0 0 1 1 1 1 Putative ephrin-receptor like F5_F8_type_C PF00754.25 EKX34713.1 - 0.063 13.4 0.0 0.12 12.5 0.0 1.5 1 1 0 1 1 1 0 F5/8 type C domain Nop14 PF04147.12 EKX34715.1 - 1 7.5 33.1 1.1 7.4 33.1 1.0 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 EKX34715.1 - 2.6 7.8 14.0 3.3 7.5 14.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 EKX34715.1 - 3.1 8.2 9.7 3.9 7.9 9.7 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 CobT PF06213.12 EKX34715.1 - 3.5 6.9 32.2 4.2 6.7 32.2 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Trypan_PARP PF05887.11 EKX34715.1 - 3.9 7.5 22.2 4.6 7.2 22.2 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Vfa1 PF08432.10 EKX34715.1 - 5.7 7.2 14.7 8 6.7 14.7 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Mpp10 PF04006.12 EKX34715.1 - 5.8 5.2 31.1 6.8 5.0 31.1 1.0 1 0 0 1 1 1 0 Mpp10 protein Tim54 PF11711.8 EKX34715.1 - 7.3 5.3 13.3 8.5 5.0 13.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SelP_N PF04592.14 EKX34715.1 - 7.3 5.9 18.8 8.4 5.7 18.8 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Presenilin PF01080.17 EKX34715.1 - 7.3 5.2 11.0 8.6 5.0 11.0 1.0 1 0 0 1 1 1 0 Presenilin Spore_coat_CotO PF14153.6 EKX34715.1 - 9.1 6.2 14.7 11 5.8 14.7 1.1 1 0 0 1 1 1 0 Spore coat protein CotO CENP-F_leu_zip PF10473.9 EKX34716.1 - 0.011 15.7 13.5 0.011 15.7 13.5 5.0 2 2 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-C4H2 PF10146.9 EKX34716.1 - 0.015 15.6 17.3 0.015 15.6 17.3 4.0 1 1 2 4 4 4 0 Zinc finger-containing protein T3SSipB PF16535.5 EKX34716.1 - 0.25 11.8 18.8 0.067 13.7 2.7 3.2 2 1 1 3 3 3 0 Type III cell invasion protein SipB ATG16 PF08614.11 EKX34716.1 - 0.53 10.5 66.8 0.12 12.6 6.5 4.3 2 2 2 4 4 4 0 Autophagy protein 16 (ATG16) DUF4559 PF15112.6 EKX34716.1 - 2.8 7.5 36.8 0.2 11.3 4.7 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4559) ADIP PF11559.8 EKX34716.1 - 3.1 7.8 64.4 0.68 10.0 4.8 5.2 2 2 3 5 5 5 0 Afadin- and alpha -actinin-Binding Laminin_II PF06009.12 EKX34716.1 - 4 7.4 40.2 0.27 11.3 4.6 4.9 2 2 3 5 5 5 0 Laminin Domain II NPV_P10 PF05531.12 EKX34716.1 - 4.3 7.9 13.4 7.7 7.1 0.3 5.1 3 2 3 6 6 6 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 EKX34716.1 - 4.8 7.3 40.6 0.14 12.2 3.0 5.1 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) MAD PF05557.13 EKX34716.1 - 6.4 5.0 70.3 0.034 12.5 6.5 3.1 1 1 2 3 3 3 0 Mitotic checkpoint protein Methyltransf_21 PF05050.12 EKX34717.1 - 2.5e-13 50.4 0.0 5.4e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase FkbM domain DUF1069 PF06370.11 EKX34717.1 - 0.053 13.1 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1069) FtsJ PF01728.19 EKX34717.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase AAA_lid_1 PF17857.1 EKX34718.1 - 0.074 13.3 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA+ lid domain Nuc_sug_transp PF04142.15 EKX34719.1 - 7.3e-73 245.5 8.9 8.1e-73 245.3 8.9 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EKX34719.1 - 2.4e-05 24.5 15.2 0.0075 16.4 4.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.6 EKX34719.1 - 0.0066 16.1 4.7 0.0082 15.8 4.3 1.5 1 1 0 1 1 1 1 Putative multidrug resistance efflux transporter PUNUT PF16913.5 EKX34719.1 - 0.022 14.0 6.1 0.028 13.6 6.1 1.1 1 0 0 1 1 1 0 Purine nucleobase transmembrane transport Aconitase_C PF00694.19 EKX34719.1 - 0.18 12.2 0.2 0.31 11.4 0.2 1.4 1 0 0 1 1 1 0 Aconitase C-terminal domain DUF202 PF02656.15 EKX34719.1 - 0.64 10.5 4.7 0.19 12.2 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF202) Phage_holin_5_1 PF06946.11 EKX34719.1 - 1.8 9.0 6.6 1.1 9.7 2.7 2.2 1 1 1 2 2 2 0 Bacteriophage A118-like holin, Hol118 MFS_2 PF13347.6 EKX34720.1 - 3.2e-26 91.9 22.8 5.6e-18 64.7 10.6 2.1 2 0 0 2 2 2 2 MFS/sugar transport protein ALIX_LYPXL_bnd PF13949.6 EKX34721.1 - 0.074 12.3 1.9 0.12 11.6 1.9 1.5 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV TPR_11 PF13414.6 EKX34721.1 - 0.1 12.3 0.2 0.2 11.4 0.2 1.4 1 0 0 1 1 1 0 TPR repeat DNA_methylase PF00145.17 EKX34721.1 - 0.16 11.3 1.8 0.35 10.2 0.7 1.9 1 1 1 2 2 2 0 C-5 cytosine-specific DNA methylase TPR_19 PF14559.6 EKX34721.1 - 0.16 12.5 2.1 0.17 12.4 0.7 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat HemY_N PF07219.13 EKX34721.1 - 1.8 8.8 5.4 1.9 8.7 3.4 2.0 2 0 0 2 2 2 0 HemY protein N-terminus DUF4230 PF14014.6 EKX34721.1 - 7 6.9 6.7 19 5.5 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4230) Apolipoprotein PF01442.18 EKX34723.1 - 0.0031 17.4 0.1 0.0069 16.3 0.1 1.5 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF948 PF06103.11 EKX34723.1 - 0.01 16.1 0.5 0.028 14.7 0.5 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) PDZ PF00595.24 EKX34727.1 - 1.5e-07 31.7 2.3 2.5e-07 31.0 1.2 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX34727.1 - 1.6e-05 25.1 0.0 3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX34727.1 - 0.022 14.6 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Mito_carr PF00153.27 EKX34728.1 - 1.3e-60 201.4 5.2 3e-20 71.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PsbM PF05151.12 EKX34729.1 - 1.7e-05 24.5 2.4 3.3e-05 23.6 2.4 1.5 1 0 0 1 1 1 1 Photosystem II reaction centre M protein (PsbM) COPIIcoated_ERV PF07970.12 EKX34730.1 - 5.5e-05 23.1 0.0 6.6e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Ras PF00071.22 EKX34731.1 - 1.3e-58 197.2 0.3 1.5e-58 197.0 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EKX34731.1 - 5.8e-36 123.3 0.2 8.6e-36 122.8 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EKX34731.1 - 4.8e-22 78.2 0.2 5.5e-22 78.0 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EKX34731.1 - 3.1e-07 30.0 0.0 3.8e-07 29.7 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EKX34731.1 - 1.3e-06 28.1 0.2 3.7e-06 26.6 0.2 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EKX34731.1 - 3e-06 27.3 0.1 6.1e-06 26.3 0.1 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EKX34731.1 - 4.1e-05 23.5 0.5 0.16 11.8 0.1 2.8 1 1 2 3 3 3 2 RsgA GTPase SRPRB PF09439.10 EKX34731.1 - 0.0005 19.5 0.1 0.0025 17.3 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EKX34731.1 - 0.0031 17.9 0.0 0.0052 17.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EKX34731.1 - 0.0038 16.9 0.1 0.014 15.1 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain FeoB_N PF02421.18 EKX34731.1 - 0.0052 16.3 0.1 0.082 12.4 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_24 PF13479.6 EKX34731.1 - 0.017 14.8 0.1 0.025 14.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 EKX34731.1 - 0.024 13.9 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_22 PF13401.6 EKX34731.1 - 0.024 14.9 0.1 0.19 12.0 0.0 2.3 1 1 1 2 2 2 0 AAA domain TniB PF05621.11 EKX34731.1 - 0.025 14.0 0.0 0.059 12.8 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 EKX34731.1 - 0.033 13.7 0.0 0.089 12.3 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 EKX34731.1 - 0.12 12.9 0.1 0.26 11.8 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 EKX34731.1 - 0.12 11.9 0.1 0.25 10.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 EKX34731.1 - 0.13 11.4 0.3 4.6 6.3 0.0 2.3 1 1 1 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.23 EKX34734.1 - 1.2e-19 70.5 0.0 2.2e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 EKX34734.1 - 9.1e-12 44.9 0.0 1.6e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 EKX34734.1 - 5e-09 35.9 0.0 8.2e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EKX34734.1 - 0.00056 20.0 0.0 0.093 12.8 0.0 2.5 1 1 0 2 2 2 2 Dynamin family MeaB PF03308.16 EKX34734.1 - 0.011 14.7 0.1 0.018 14.0 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Guanylate_cyc PF00211.20 EKX34735.1 - 6.2e-14 52.0 0.0 1.1e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 EKX34736.1 - 6.4e-10 39.2 0.0 6.8e-10 39.1 0.0 1.0 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EKX34736.1 - 0.0009 19.2 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EKX34736.1 - 0.036 14.1 0.0 0.046 13.8 0.0 1.2 1 0 0 1 1 1 0 PAS domain PAS_3 PF08447.12 EKX34736.1 - 0.051 13.9 0.0 0.079 13.2 0.0 1.4 1 1 0 1 1 1 0 PAS fold PAS_4 PF08448.10 EKX34736.1 - 0.12 12.7 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 PAS fold Y_phosphatase3 PF13350.6 EKX34737.1 - 1.1e-05 25.5 0.0 1.3e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EKX34737.1 - 1.9e-05 24.5 0.0 2.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX34737.1 - 0.00054 19.6 0.0 0.001 18.7 0.0 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX34737.1 - 0.011 15.9 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate CDKN3 PF05706.12 EKX34737.1 - 0.044 13.5 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase2 PF03162.13 EKX34737.1 - 0.075 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family IHO1 PF15771.5 EKX34738.1 - 0.01 14.6 1.2 0.015 14.1 1.2 1.2 1 0 0 1 1 1 0 Interactor of HORMAD1 protein 1 T_Ag_DNA_bind PF02217.16 EKX34739.1 - 0.21 12.2 0.5 0.25 12.0 0.5 1.2 1 0 0 1 1 1 0 Origin of replication binding protein Zn_clus PF00172.18 EKX34740.1 - 1.2e-11 44.5 27.1 9.5e-06 25.6 10.4 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain RolB_RolC PF02027.17 EKX34740.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 RolB/RolC glucosidase family FXMRP1_C_core PF12235.8 EKX34743.1 - 0.02 15.6 2.3 0.02 15.6 2.3 1.9 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal DUF4108 PF13390.6 EKX34743.1 - 0.065 13.1 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4108) zf-HIT PF04438.16 EKX34743.1 - 0.94 9.4 7.3 0.19 11.7 3.2 1.8 2 0 0 2 2 2 0 HIT zinc finger Bromodomain PF00439.25 EKX34744.1 - 3.2e-09 36.8 2.3 4.4e-07 29.9 0.3 2.7 2 0 0 2 2 2 2 Bromodomain zf-C2H2_jaz PF12171.8 EKX34744.1 - 1.6e-05 25.0 3.7 0.0076 16.5 0.0 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding PHD PF00628.29 EKX34744.1 - 0.00086 19.2 3.6 0.00086 19.2 3.6 3.9 4 0 0 4 4 4 1 PHD-finger PHD_2 PF13831.6 EKX34744.1 - 0.0081 15.7 0.5 0.0081 15.7 0.5 3.4 5 0 0 5 5 5 1 PHD-finger zf-C2H2_2 PF12756.7 EKX34744.1 - 0.019 15.3 0.9 29 5.1 0.1 3.6 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_9 PF14369.6 EKX34744.1 - 0.04 14.2 5.9 8.7 6.7 0.1 3.8 3 0 0 3 3 3 0 zinc-ribbon zf-C2H2 PF00096.26 EKX34744.1 - 0.058 13.9 0.2 0.058 13.9 0.2 4.6 5 0 0 5 5 5 0 Zinc finger, C2H2 type Prok-RING_1 PF14446.6 EKX34744.1 - 0.35 10.8 10.7 0.031 14.2 3.7 2.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 EKX34744.1 - 0.67 9.6 5.3 4.1 7.0 3.3 2.9 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain DUF1829 PF08862.10 EKX34744.1 - 2.6 8.6 6.0 2.3 8.8 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function DUF1829 SIR2 PF02146.17 EKX34745.1 - 1.2e-51 175.2 0.0 1.8e-51 174.6 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EKX34745.1 - 0.0033 17.2 0.0 1.2 8.8 0.0 2.5 2 1 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Zn_clus PF00172.18 EKX34747.1 - 1.8e-08 34.3 11.3 3.8e-08 33.3 11.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RolB_RolC PF02027.17 EKX34747.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 RolB/RolC glucosidase family DUF872 PF05915.12 EKX34749.1 - 5.7e-15 55.5 4.2 7.6e-15 55.1 4.2 1.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) ThrE_2 PF12821.7 EKX34749.1 - 0.02 15.1 1.2 0.034 14.3 1.2 1.5 1 1 0 1 1 1 0 Threonine/Serine exporter, ThrE DUF3040 PF11239.8 EKX34749.1 - 0.34 11.2 2.8 1.4 9.3 2.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3040) DUF2502 PF10697.9 EKX34750.1 - 0.17 12.3 1.0 0.36 11.2 0.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2502) Kunitz_BPTI PF00014.23 EKX34750.1 - 0.64 10.3 5.9 20 5.5 0.1 3.1 2 1 0 2 2 2 0 Kunitz/Bovine pancreatic trypsin inhibitor domain MORN PF02493.20 EKX34751.1 - 1.5e-56 185.0 63.3 1.1e-07 31.3 0.2 12.5 10 2 3 13 13 13 11 MORN repeat DUF448 PF04296.13 EKX34751.1 - 0.83 9.6 2.8 20 5.1 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF448) CopK PF11525.8 EKX34751.1 - 2.2 8.0 5.5 1.5 8.5 0.3 2.9 3 0 0 3 3 3 0 Copper resistance protein K PBCV_basic_adap PF08789.10 EKX34751.1 - 2.8 8.1 6.8 13 6.0 0.0 3.4 3 0 0 3 3 3 0 PBCV-specific basic adaptor domain 4HBT PF03061.22 EKX34752.1 - 2.4e-06 27.8 0.0 2.9e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase superfamily Zn_clus PF00172.18 EKX34753.1 - 5.3e-12 45.7 19.1 1.7e-07 31.3 7.5 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain CCDC-167 PF15188.6 EKX34754.1 - 0.076 13.4 0.8 0.18 12.2 0.6 1.8 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 O-FucT PF10250.9 EKX34754.1 - 0.084 12.6 0.7 0.13 11.9 0.7 1.3 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase DUF4004 PF13171.6 EKX34754.1 - 0.085 13.1 0.2 0.14 12.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4004) DUF2959 PF11172.8 EKX34754.1 - 0.093 12.9 2.4 0.16 12.1 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) LCIB_C_CA PF18599.1 EKX34754.1 - 0.32 10.3 1.1 0.49 9.7 1.1 1.3 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases CHASE7 PF17151.4 EKX34756.1 - 0.0058 16.3 1.8 0.01 15.5 1.8 1.3 1 0 0 1 1 1 1 Periplasmic sensor domain DUF4164 PF13747.6 EKX34756.1 - 0.039 14.2 9.5 0.094 13.0 8.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) T6PP_N PF18572.1 EKX34756.1 - 0.12 12.2 4.9 0.21 11.5 4.1 1.8 1 1 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain FapA PF03961.13 EKX34756.1 - 0.27 9.8 3.7 0.35 9.4 3.7 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A CENP-Q PF13094.6 EKX34756.1 - 0.31 11.2 15.5 0.013 15.8 8.7 2.0 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit HTH_Tnp_Tc5 PF03221.16 EKX34757.1 - 1.3e-07 31.6 1.1 2.3e-07 30.7 0.3 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 EKX34757.1 - 0.0011 18.5 0.6 0.0076 15.9 0.1 2.1 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain MarR_2 PF12802.7 EKX34757.1 - 0.026 14.4 0.1 5.1 7.1 0.0 2.5 2 0 0 2 2 2 0 MarR family HTH_38 PF13936.6 EKX34757.1 - 0.029 14.1 1.3 0.44 10.3 0.2 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain EnY2 PF10163.9 EKX34757.1 - 0.087 13.2 0.8 0.18 12.2 0.2 1.8 2 0 0 2 2 2 0 Transcription factor e(y)2 HTH_3 PF01381.22 EKX34757.1 - 0.11 12.6 0.4 0.35 10.9 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix HTH_Tnp_Tc5 PF03221.16 EKX34758.1 - 1.3e-07 31.5 1.1 2.2e-07 30.8 0.3 1.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 EKX34758.1 - 0.0011 18.6 0.6 0.0073 15.9 0.1 2.1 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 EKX34758.1 - 0.025 14.3 1.3 0.43 10.4 0.2 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 EKX34758.1 - 0.027 14.3 0.2 4.9 7.1 0.0 2.5 2 1 0 2 2 2 0 MarR family EnY2 PF10163.9 EKX34758.1 - 0.082 13.3 0.8 0.18 12.2 0.2 1.8 2 0 0 2 2 2 0 Transcription factor e(y)2 HTH_3 PF01381.22 EKX34758.1 - 0.1 12.6 0.4 0.34 11.0 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix Chloroa_b-bind PF00504.21 EKX34760.1 - 1.7e-43 148.9 0.0 2.6e-43 148.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DnaJ PF00226.31 EKX34761.1 - 2.6e-24 85.1 2.4 3.5e-24 84.7 2.4 1.2 1 0 0 1 1 1 1 DnaJ domain Fip1 PF05182.13 EKX34763.1 - 2.7e-23 81.2 1.6 3.3e-23 80.9 1.6 1.1 1 0 0 1 1 1 1 Fip1 motif DUF3759 PF12585.8 EKX34764.1 - 0.043 13.8 0.0 0.09 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3759) Nebulin PF00880.18 EKX34765.1 - 0.84 9.6 4.5 4.1 7.4 1.7 2.5 2 0 0 2 2 2 0 Nebulin repeat LANC_like PF05147.13 EKX34766.1 - 8.8e-44 149.5 0.0 1.6e-43 148.6 0.0 1.4 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein YfcL PF08891.11 EKX34766.1 - 0.0032 17.8 0.1 0.0064 16.8 0.1 1.5 1 0 0 1 1 1 1 YfcL protein DUF4823 PF16105.5 EKX34767.1 - 0.072 13.0 0.1 0.086 12.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4823) Chloroa_b-bind PF00504.21 EKX34768.1 - 2.8e-41 141.7 0.1 5.9e-41 140.7 0.1 1.5 1 1 0 1 1 1 1 Chlorophyll A-B binding protein Orf78 PF06024.12 EKX34771.1 - 0.00097 19.4 1.2 0.0014 18.9 1.2 1.3 1 0 0 1 1 1 1 Orf78 (ac78) Amnionless PF14828.6 EKX34771.1 - 0.02 13.7 1.3 0.024 13.5 1.3 1.1 1 0 0 1 1 1 0 Amnionless Shisa PF13908.6 EKX34771.1 - 0.021 15.1 3.1 0.026 14.8 3.1 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 EKX34771.1 - 0.022 14.7 2.5 0.034 14.0 2.5 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF3671 PF12420.8 EKX34771.1 - 0.11 12.6 3.5 0.16 12.0 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF2371 PF10177.9 EKX34771.1 - 0.13 12.4 1.4 0.16 12.1 1.1 1.3 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) DUF2853 PF11015.8 EKX34771.1 - 0.15 12.7 0.3 0.26 11.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2853) DUF4870 PF09685.10 EKX34771.1 - 0.22 11.6 6.8 0.14 12.3 4.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4870) ODV-E18 PF10717.9 EKX34771.1 - 0.24 11.3 8.3 0.36 10.7 8.3 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 HemY_N PF07219.13 EKX34771.1 - 0.26 11.5 1.4 0.4 10.9 1.4 1.3 1 0 0 1 1 1 0 HemY protein N-terminus Lig_chan PF00060.26 EKX34771.1 - 0.29 11.0 2.7 0.25 11.2 1.2 1.6 1 1 0 1 1 1 0 Ligand-gated ion channel UL45 PF05473.12 EKX34771.1 - 1 9.0 6.7 1.4 8.5 6.7 1.2 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like Protocadherin PF08374.11 EKX34771.1 - 1.4 8.8 5.4 1.8 8.5 5.4 1.2 1 0 0 1 1 1 0 Protocadherin EssA PF10661.9 EKX34771.1 - 6.6 6.6 8.3 49 3.8 7.9 2.0 1 1 1 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA DUF4924 PF16271.5 EKX34773.1 - 0.064 13.3 0.0 0.086 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4924) EF-hand_1 PF00036.32 EKX34774.1 - 1.4e-11 43.1 0.1 5.1e-06 25.7 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX34774.1 - 7.9e-11 42.3 0.1 1.1e-10 41.7 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX34774.1 - 8.2e-09 34.7 0.0 1.4e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EKX34774.1 - 1.7e-06 27.3 0.1 0.00029 20.2 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX34774.1 - 0.12 12.2 0.2 2.2 8.2 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain pair NDK PF00334.19 EKX34775.1 - 8.7e-55 184.4 0.0 1e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Methyltransf_32 PF13679.6 EKX34776.1 - 4.2e-15 56.1 0.0 8.5e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX34776.1 - 3.1e-05 23.8 0.0 7.2e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX34776.1 - 0.00019 22.1 0.0 0.00058 20.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EKX34776.1 - 0.0089 15.8 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 EKX34776.1 - 0.057 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW CMAS PF02353.20 EKX34776.1 - 0.061 12.6 0.1 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 EKX34776.1 - 0.13 12.9 0.1 0.36 11.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain PseudoU_synth_2 PF00849.22 EKX34777.1 - 3.9e-07 30.3 0.0 0.023 14.8 0.0 2.5 2 1 1 3 3 3 2 RNA pseudouridylate synthase CAF1C_H4-bd PF12265.8 EKX34778.1 - 2e-26 92.0 3.1 2.3e-26 91.8 0.4 2.5 2 1 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EKX34778.1 - 1e-20 73.6 13.5 9.8e-05 23.1 0.3 6.2 4 2 1 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX34778.1 - 0.00013 22.2 2.0 0.28 11.5 0.1 3.9 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EKX34778.1 - 0.0056 15.5 0.0 0.011 14.5 0.0 1.4 1 1 0 1 1 1 1 Nup133 N terminal like Pkinase PF00069.25 EKX34780.1 - 2.6e-38 131.9 0.0 3.3e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX34780.1 - 9.9e-36 123.3 0.2 1.8e-35 122.5 0.1 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX34780.1 - 2.4e-05 23.8 0.1 0.00025 20.5 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EKX34780.1 - 0.0013 18.1 0.6 0.003 17.0 0.2 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EKX34780.1 - 0.011 14.5 0.0 0.014 14.2 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 EKX34780.1 - 0.03 13.9 0.0 0.069 12.7 0.0 1.6 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EKX34780.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-LSD1 PF06943.12 EKX34781.1 - 1.2e-12 47.4 7.1 3.7e-12 45.9 1.7 2.2 2 0 0 2 2 2 1 LSD1 zinc finger RNA_POL_M_15KD PF02150.16 EKX34781.1 - 0.0013 18.5 0.5 0.24 11.3 0.3 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Elf1 PF05129.13 EKX34781.1 - 0.0042 17.1 0.7 0.25 11.4 0.1 2.1 1 1 1 2 2 2 1 Transcription elongation factor Elf1 like zf-Sec23_Sec24 PF04810.15 EKX34781.1 - 0.02 14.9 4.1 2.6 8.2 0.0 2.8 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger Ribosomal_S27e PF01667.17 EKX34781.1 - 0.051 13.3 2.3 0.15 11.8 0.4 2.1 2 0 0 2 2 2 0 Ribosomal protein S27 zf-DNA_Pol PF08996.10 EKX34781.1 - 0.12 12.1 0.5 0.16 11.7 0.5 1.1 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger zf-MIZ PF02891.20 EKX34781.1 - 0.14 12.0 2.0 5.6 6.8 0.3 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger HalOD2 PF18547.1 EKX34781.1 - 0.16 11.9 0.3 0.16 11.9 0.3 2.4 3 0 0 3 3 3 0 Halobacterial output domain 2 A2L_zn_ribbon PF08792.10 EKX34781.1 - 0.33 10.7 3.8 1 9.2 0.2 2.7 3 0 0 3 3 3 0 A2L zinc ribbon domain zinc_ribbon_5 PF13719.6 EKX34781.1 - 3.6 7.4 8.3 43 4.0 4.1 3.1 2 1 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 EKX34781.1 - 4.3 7.4 6.5 24 5.0 3.3 2.9 2 1 0 2 2 2 0 zinc-ribbon domain ECH_2 PF16113.5 EKX34782.1 - 1.4e-50 172.7 0.0 1.6e-50 172.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EKX34782.1 - 2e-20 73.1 0.0 3e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Vps53_N PF04100.12 EKX34783.1 - 2.5e-05 23.4 0.3 2.5e-05 23.4 0.3 3.1 1 1 2 3 3 3 1 Vps53-like, N-terminal CTP_transf_1 PF01148.20 EKX34783.1 - 0.37 10.5 7.2 0.65 9.7 7.2 1.3 1 0 0 1 1 1 0 Cytidylyltransferase family DUF2663 PF10864.8 EKX34783.1 - 1.1 9.7 10.2 0.26 11.7 6.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) Pam16 PF03656.13 EKX34784.1 - 3.6e-07 30.2 0.0 4e-07 30.1 0.0 1.0 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 EKX34784.1 - 8.6e-07 29.0 0.0 1.5e-06 28.2 0.0 1.3 1 1 0 1 1 1 1 DnaJ domain HTH_10 PF04967.12 EKX34784.1 - 0.16 11.8 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 HTH DNA binding domain HTH_8 PF02954.19 EKX34784.1 - 0.16 11.8 0.1 0.26 11.1 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Chloroa_b-bind PF00504.21 EKX34785.1 - 4.3e-43 147.6 0.1 6.5e-43 147.0 0.1 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Yae1_N PF09811.9 EKX34786.1 - 2e-05 24.2 1.7 2e-05 24.2 1.7 2.6 3 0 0 3 3 3 1 Essential protein Yae1, N terminal DUF5320 PF17253.2 EKX34786.1 - 8.1 7.6 8.9 3.3 8.8 2.2 2.9 1 1 1 2 2 2 0 Family of unknown function (DUF5320) CD20 PF04103.15 EKX34787.1 - 0.0099 16.0 13.1 0.0099 16.0 13.1 2.7 1 1 1 2 2 2 1 CD20-like family SUR7 PF06687.12 EKX34787.1 - 0.024 14.3 5.6 0.037 13.7 5.6 1.4 1 1 0 1 1 1 0 SUR7/PalI family DUF3367 PF11847.8 EKX34787.1 - 0.077 10.9 0.2 0.11 10.4 0.2 1.1 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase FKBP_C PF00254.28 EKX34788.1 - 2.2e-07 31.1 0.0 2.6e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase GIDA PF01134.22 EKX34789.1 - 0.037 13.1 0.1 0.039 13.0 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A MS_channel PF00924.18 EKX34789.1 - 0.17 11.4 1.6 0.21 11.1 1.6 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel TMEM208_SND2 PF05620.11 EKX34789.1 - 9.7 5.9 6.7 15 5.3 6.7 1.3 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 UN_NPL4 PF11543.8 EKX34790.1 - 0.072 13.6 0.2 15 6.1 0.1 2.6 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 tRNA-synt_1 PF00133.22 EKX34791.1 - 7e-150 500.2 2.3 1e-148 496.3 2.3 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 EKX34791.1 - 5.4e-12 45.6 0.0 1.8e-08 34.1 0.0 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 PDZ_6 PF17820.1 EKX34791.1 - 6.8e-12 45.1 4.5 1.7e-08 34.2 0.2 3.0 2 1 0 2 2 2 2 PDZ domain tRNA-synt_1g PF09334.11 EKX34791.1 - 2.2e-11 43.1 0.6 3.5e-07 29.3 0.0 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (M) PDZ PF00595.24 EKX34791.1 - 6.7e-10 39.2 1.8 4.7e-07 30.1 0.4 2.8 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX34791.1 - 3.9e-08 33.5 0.3 5.8e-05 23.3 0.1 2.5 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 EKX34791.1 - 4e-06 26.7 0.1 0.11 12.4 0.0 2.7 2 0 0 2 2 2 2 Tricorn protease PDZ domain tRNA-synt_1e PF01406.19 EKX34791.1 - 0.028 13.8 0.0 0.088 12.1 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1c PF00749.21 EKX34791.1 - 0.081 11.8 0.1 0.79 8.6 0.0 2.3 1 1 1 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain DUF4407 PF14362.6 EKX34791.1 - 3.9 6.7 5.0 61 2.8 6.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.12 EKX34791.1 - 5.9 6.6 9.8 11 5.8 9.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Histone PF00125.24 EKX34792.1 - 9.1e-42 142.5 0.7 1.1e-41 142.3 0.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EKX34792.1 - 0.00062 19.9 0.1 0.00078 19.5 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EKX34792.1 - 0.034 14.4 0.0 0.046 14.0 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ALIX_LYPXL_bnd PF13949.6 EKX34795.1 - 0.0046 16.3 4.0 0.0066 15.8 4.0 1.1 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV NB-LRR PF12061.8 EKX34795.1 - 0.12 11.7 0.4 0.17 11.2 0.4 1.2 1 0 0 1 1 1 0 Late blight resistance protein R1 Lipase_3 PF01764.25 EKX34799.1 - 0.12 12.2 0.0 0.84 9.5 0.0 2.3 2 1 0 2 2 2 0 Lipase (class 3) Blt1_C PF17183.4 EKX34799.1 - 0.15 11.7 1.6 0.17 11.5 0.1 1.8 2 0 0 2 2 2 0 Get5 carboxyl domain PIG-S PF10510.9 EKX34800.1 - 0.018 13.9 0.4 0.036 12.9 0.2 1.5 1 1 1 2 2 2 0 Phosphatidylinositol-glycan biosynthesis class S protein DUF641 PF04859.12 EKX34800.1 - 0.23 11.8 2.5 0.5 10.7 2.5 1.6 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) UPF0113_N PF17833.1 EKX34800.1 - 0.46 11.1 2.2 1.9 9.1 0.1 2.5 2 1 1 3 3 3 0 UPF0113 Pre-PUA domain DUF2501 PF10696.9 EKX34801.1 - 0.18 12.1 0.1 0.42 10.9 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2501) AAA-ATPase_like PF09820.9 EKX34802.1 - 0.031 13.7 6.6 0.049 13.0 0.0 2.6 2 0 0 2 2 2 0 Predicted AAA-ATPase Ephrin_rec_like PF07699.13 EKX34803.1 - 5.4e-23 80.5 46.2 6.9e-07 28.9 6.7 5.8 1 1 4 6 6 6 6 Putative ephrin-receptor like VSP PF03302.13 EKX34803.1 - 0.0013 17.7 38.7 0.085 11.7 14.3 2.3 1 1 1 2 2 2 2 Giardia variant-specific surface protein TNFR_c6 PF00020.18 EKX34803.1 - 0.0042 17.4 32.4 0.23 11.9 0.5 6.6 3 2 4 7 7 7 4 TNFR/NGFR cysteine-rich region PHD PF00628.29 EKX34803.1 - 0.025 14.5 0.7 0.025 14.5 0.7 4.2 4 2 0 4 4 4 0 PHD-finger C1_1 PF00130.22 EKX34803.1 - 0.52 10.2 22.7 0.18 11.7 0.8 4.2 3 2 1 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ephrin_rec_like PF07699.13 EKX34804.1 - 5.5e-166 538.3 609.3 3.4e-11 42.7 1.0 62.2 45 12 18 64 64 64 50 Putative ephrin-receptor like EGF_CA PF07645.15 EKX34804.1 - 3.1e-07 30.5 8.1 3.1e-07 30.5 8.1 37.5 44 2 0 44 44 44 1 Calcium-binding EGF domain NCD3G PF07562.14 EKX34804.1 - 0.0018 18.2 3.3 0.0018 18.2 3.3 53.5 43 7 12 59 59 59 34 Nine Cysteines Domain of family 3 GPCR EGF_MSP1_1 PF12946.7 EKX34804.1 - 0.0022 18.0 4.3 0.0022 18.0 4.3 30.2 36 0 0 36 36 36 4 MSP1 EGF domain 1 Ephrin_rec_like PF07699.13 EKX34805.1 - 1.8e-27 94.8 79.1 2.2e-07 30.5 6.1 8.7 1 1 6 8 8 8 8 Putative ephrin-receptor like NCD3G PF07562.14 EKX34805.1 - 5.7e-07 29.4 56.2 0.094 12.7 7.3 6.7 3 3 2 7 7 7 6 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX34805.1 - 7.5e-06 26.2 54.0 0.29 11.6 5.1 9.6 5 3 2 8 8 8 5 TNFR/NGFR cysteine-rich region zf-C2HCIx2C PF10782.9 EKX34805.1 - 0.069 13.1 0.2 0.069 13.1 0.2 5.0 3 1 2 5 5 5 0 Zinc-finger VSP PF03302.13 EKX34805.1 - 8.8 5.1 68.5 1.6 7.5 18.2 3.8 1 1 1 3 3 3 0 Giardia variant-specific surface protein EXS PF03124.14 EKX34806.1 - 0.96 8.7 8.3 0.84 8.9 7.0 1.4 1 1 0 1 1 1 0 EXS family Peroxin-3 PF04882.12 EKX34807.1 - 0.0019 17.3 1.3 0.0026 16.8 1.3 1.1 1 0 0 1 1 1 1 Peroxin-3 DUF1694 PF07997.11 EKX34809.1 - 0.023 14.7 0.1 0.04 14.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1694) SchA_CurD PF04486.12 EKX34809.1 - 0.066 13.3 0.2 0.12 12.4 0.0 1.5 2 0 0 2 2 2 0 SchA/CurD like domain Vfa1 PF08432.10 EKX34812.1 - 0.12 12.7 7.7 0.17 12.2 7.7 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Rtt102p PF09510.10 EKX34812.1 - 0.47 10.7 5.6 0.75 10.0 5.6 1.2 1 0 0 1 1 1 0 Rtt102p-like transcription regulator protein DUF2115 PF09888.9 EKX34812.1 - 0.91 10.0 11.1 43 4.6 0.0 2.3 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Spt20 PF12090.8 EKX34814.1 - 0.021 14.5 2.1 0.04 13.5 2.1 1.4 1 0 0 1 1 1 0 Spt20 family ALO PF04030.14 EKX34814.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase V_ATPase_I PF01496.19 EKX34814.1 - 0.39 8.6 10.9 0.61 7.9 10.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Katanin_con80 PF13925.6 EKX34814.1 - 5.6 7.0 6.5 7.8 6.5 0.8 3.1 1 1 1 2 2 2 0 con80 domain of Katanin TolA_bind_tri PF16331.5 EKX34815.1 - 0.0026 17.8 3.3 0.0082 16.2 0.7 2.4 2 0 0 2 2 2 1 TolA binding protein trimerisation DivIC PF04977.15 EKX34815.1 - 0.026 14.3 6.2 1.9 8.3 0.2 2.8 3 0 0 3 3 3 0 Septum formation initiator PhaP_Bmeg PF09602.10 EKX34815.1 - 0.05 13.5 3.0 0.11 12.5 3.1 1.5 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) ZapB PF06005.12 EKX34815.1 - 0.062 13.7 6.4 0.34 11.4 1.4 2.6 2 0 0 2 2 2 0 Cell division protein ZapB Ax_dynein_light PF10211.9 EKX34815.1 - 0.072 13.0 4.3 0.082 12.8 1.8 2.2 2 0 0 2 2 2 0 Axonemal dynein light chain UPF0184 PF03670.13 EKX34815.1 - 0.15 12.5 2.8 1.4 9.4 2.1 2.8 2 1 1 3 3 2 0 Uncharacterised protein family (UPF0184) Atg14 PF10186.9 EKX34815.1 - 0.28 10.2 2.7 8.2 5.4 0.1 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 BBS1 PF14779.6 EKX34815.1 - 0.29 10.5 0.9 0.44 9.9 0.9 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 Nup54 PF13874.6 EKX34815.1 - 0.33 11.0 5.7 0.14 12.3 2.7 1.8 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 DUF948 PF06103.11 EKX34815.1 - 0.65 10.3 2.2 0.71 10.2 0.9 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) AKNA PF12443.8 EKX34815.1 - 1.1 10.0 4.6 0.49 11.1 1.1 2.2 2 1 1 3 3 2 0 AT-hook-containing transcription factor Herpes_BLRF2 PF05812.12 EKX34815.1 - 1.1 9.4 5.3 1.3 9.1 0.1 2.7 3 0 0 3 3 3 0 Herpesvirus BLRF2 protein SlyX PF04102.12 EKX34815.1 - 1.2 9.8 5.5 5.4 7.7 0.1 2.7 2 1 0 2 2 2 0 SlyX YabA PF06156.13 EKX34815.1 - 2.1 9.1 11.4 12 6.6 4.5 2.5 1 1 1 2 2 2 0 Initiation control protein YabA Spc24 PF08286.11 EKX34815.1 - 2.4 8.5 5.3 1.6 9.0 1.3 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 KIAA1430 PF13879.6 EKX34815.1 - 2.8 8.7 10.4 9.3 7.1 10.4 1.9 1 1 0 1 1 1 0 KIAA1430 homologue Nup96 PF12110.8 EKX34817.1 - 0.003 16.7 0.1 0.0059 15.8 0.1 1.4 1 0 0 1 1 1 1 Nuclear protein 96 DUF2461 PF09365.10 EKX34818.1 - 0.095 12.6 0.1 0.52 10.2 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical protein (DUF2461) DUF2700 PF10912.8 EKX34819.1 - 6 6.9 10.9 0.051 13.6 2.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2700) Trypan_PARP PF05887.11 EKX34820.1 - 0.071 13.1 7.9 0.12 12.3 7.6 1.6 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF717 PF05338.12 EKX34820.1 - 0.17 12.1 0.2 0.87 9.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF717) Rib_recp_KP_reg PF05104.12 EKX34820.1 - 0.34 11.9 14.7 0.052 14.6 10.0 1.9 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region Med11 PF10280.9 EKX34820.1 - 0.37 11.3 4.4 0.1 13.1 1.0 1.8 2 0 0 2 2 2 0 Mediator complex protein PDDEXK_3 PF13366.6 EKX34821.1 - 1.9e-08 34.6 0.0 4.2e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily PAP_RNA-bind PF04926.15 EKX34823.1 - 0.078 12.6 0.2 0.14 11.7 0.2 1.5 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain DUF3902 PF13042.6 EKX34823.1 - 0.1 12.1 0.2 0.1 12.1 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3902) G0-G1_switch_2 PF15103.6 EKX34823.1 - 0.13 12.7 1.8 18 5.8 0.1 2.5 2 0 0 2 2 2 0 G0/G1 switch protein 2 CDC45 PF02724.14 EKX34823.1 - 0.17 10.2 2.5 0.24 9.7 2.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Ureide_permease PF07168.11 EKX34823.1 - 0.18 10.5 4.8 0.085 11.6 0.2 2.1 1 1 1 2 2 2 0 Ureide permease Glycos_transf_4 PF00953.21 EKX34823.1 - 2.1 8.3 13.9 0.22 11.5 1.7 3.0 2 1 1 3 3 3 0 Glycosyl transferase family 4 Peptidase_S78 PF04586.17 EKX34829.1 - 0.002 18.3 0.0 0.0026 18.0 0.0 1.1 1 0 0 1 1 1 1 Caudovirus prohead serine protease T6SS_Vgr PF13296.6 EKX34829.1 - 0.014 15.5 0.0 0.032 14.3 0.0 1.6 2 0 0 2 2 2 0 Putative type VI secretion system Rhs element Vgr SNAPc19 PF15497.6 EKX34832.1 - 0.003 18.0 1.8 0.0035 17.8 1.8 1.1 1 0 0 1 1 1 1 snRNA-activating protein complex subunit 19, SNAPc subunit 19 FRG1 PF06229.12 EKX34832.1 - 0.01 15.6 6.7 0.011 15.5 6.7 1.0 1 0 0 1 1 1 0 FRG1-like domain CENP-H PF05837.12 EKX34832.1 - 0.012 16.1 5.9 0.013 15.9 5.9 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Atg14 PF10186.9 EKX34832.1 - 0.068 12.2 8.7 0.081 12.0 8.7 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TarH PF02203.15 EKX34832.1 - 0.082 12.8 2.7 0.092 12.7 2.7 1.1 1 0 0 1 1 1 0 Tar ligand binding domain homologue DUF1897 PF09005.10 EKX34832.1 - 0.18 11.3 1.1 0.35 10.4 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1897) Baculo_F PF12259.8 EKX34832.1 - 0.21 10.1 2.3 0.21 10.1 2.3 1.0 1 0 0 1 1 1 0 Baculovirus F protein APG6_N PF17675.1 EKX34832.1 - 0.23 12.0 10.5 0.43 11.1 10.5 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4407 PF14362.6 EKX34832.1 - 0.39 10.0 5.0 0.52 9.6 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 EKX34832.1 - 0.46 10.8 10.5 0.47 10.8 10.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) UPF0242 PF06785.11 EKX34832.1 - 0.78 9.8 8.9 0.9 9.6 8.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMPIT PF07851.13 EKX34832.1 - 0.87 8.8 5.8 0.91 8.7 5.8 1.0 1 0 0 1 1 1 0 TMPIT-like protein RRP14 PF15459.6 EKX34832.1 - 2.8 8.6 13.6 0.47 11.1 9.5 1.9 1 1 1 2 2 2 0 60S ribosome biogenesis protein Rrp14 COX16 PF14138.6 EKX34832.1 - 2.8 8.5 6.0 4.2 8.0 6.0 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 DUF4140 PF13600.6 EKX34832.1 - 3.8 8.0 8.0 21 5.6 8.0 2.0 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 EKX34832.1 - 4.6 7.1 11.0 16 5.4 5.1 2.2 1 1 1 2 2 2 0 Septum formation initiator Snf7 PF03357.21 EKX34834.1 - 2.8e-15 56.4 7.0 4.3e-15 55.7 7.0 1.2 1 0 0 1 1 1 1 Snf7 AAA_18 PF13238.6 EKX34835.1 - 3e-09 37.5 0.1 3.7e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EKX34835.1 - 0.00069 19.9 0.0 0.00093 19.5 0.0 1.3 1 1 0 1 1 1 1 AAA domain P-mevalo_kinase PF04275.14 EKX34835.1 - 0.0024 17.8 0.5 0.011 15.7 0.5 2.0 1 1 0 1 1 1 1 Phosphomevalonate kinase AAA_17 PF13207.6 EKX34835.1 - 0.0099 16.3 0.0 0.034 14.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 EKX34835.1 - 0.025 14.4 0.0 0.038 13.8 0.0 1.4 1 1 0 1 1 1 0 Deoxynucleoside kinase AAA_33 PF13671.6 EKX34835.1 - 0.041 14.1 0.0 0.054 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EKX34835.1 - 0.16 12.3 0.5 0.87 9.9 0.5 2.1 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EKX34835.1 - 0.19 10.9 0.8 0.66 9.1 0.8 1.8 1 1 0 1 1 1 0 NB-ARC domain CopD PF05425.13 EKX34836.1 - 0.015 15.7 0.3 0.024 15.0 0.3 1.3 1 0 0 1 1 1 0 Copper resistance protein D TCO89 PF10452.9 EKX34836.1 - 0.15 11.0 0.1 0.2 10.6 0.1 1.1 1 0 0 1 1 1 0 TORC1 subunit TCO89 Stn1 PF10451.9 EKX34839.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Telomere regulation protein Stn1 DUF3877 PF12993.7 EKX34840.1 - 0.0017 18.2 0.4 0.002 18.0 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function, E. rectale Gene description (DUF3877) ACAS_N PF16177.5 EKX34840.1 - 0.083 12.8 0.0 0.2 11.6 0.0 1.6 2 0 0 2 2 2 0 Acetyl-coenzyme A synthetase N-terminus SAP18 PF06487.12 EKX34843.1 - 0.004 17.3 0.0 0.0079 16.4 0.0 1.5 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) DUF2206 PF09971.9 EKX34845.1 - 0.73 8.5 2.6 1.1 8.0 2.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) BST2 PF16716.5 EKX34846.1 - 0.61 10.7 6.3 11 6.7 0.2 3.0 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 DUF1451 PF07295.11 EKX34848.1 - 0.0052 16.8 2.1 0.028 14.5 0.2 2.2 2 0 0 2 2 2 1 Zinc-ribbon containing domain Med8 PF10232.9 EKX34848.1 - 0.027 14.0 1.5 0.09 12.4 0.1 1.9 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 PEP-utilisers_N PF05524.13 EKX34848.1 - 0.076 13.2 1.8 0.29 11.3 0.1 2.2 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF883 PF05957.13 EKX34848.1 - 0.12 13.0 9.2 2.7 8.7 1.8 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Atrophin-1 PF03154.15 EKX34848.1 - 0.14 10.4 3.9 0.26 9.6 1.1 1.9 2 0 0 2 2 2 0 Atrophin-1 family DUF2175 PF09943.9 EKX34848.1 - 0.32 11.3 2.0 0.44 10.9 0.1 2.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) Grg1 PF11034.8 EKX34848.1 - 0.74 10.1 15.8 2.1 8.6 0.0 4.1 3 1 1 4 4 4 0 Glucose-repressible protein Grg1 Ephrin_rec_like PF07699.13 EKX34850.1 - 2.8e-34 116.6 72.5 4.9e-10 39.0 6.7 8.0 6 2 2 8 8 8 7 Putative ephrin-receptor like NCD3G PF07562.14 EKX34850.1 - 0.002 18.1 62.1 0.04 13.9 0.6 9.0 7 1 3 10 10 10 5 Nine Cysteines Domain of family 3 GPCR EGF_MSP1_1 PF12946.7 EKX34850.1 - 0.05 13.6 1.0 0.05 13.6 1.0 7.9 7 2 2 9 9 9 0 MSP1 EGF domain 1 TNFR_c6 PF00020.18 EKX34850.1 - 3.1 8.3 59.3 0.2 12.1 3.3 10.3 5 3 3 9 9 9 0 TNFR/NGFR cysteine-rich region Ephrin_rec_like PF07699.13 EKX34851.1 - 6e-17 61.1 34.4 2.4e-08 33.6 9.7 12.1 7 3 4 12 12 12 5 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX34851.1 - 0.0068 16.8 6.8 0.0068 16.8 6.8 13.6 6 4 9 15 15 15 7 TNFR/NGFR cysteine-rich region Ephrin_rec_like PF07699.13 EKX34852.1 - 2.6e-75 248.0 263.5 4e-10 39.3 1.3 24.4 18 5 6 24 24 24 20 Putative ephrin-receptor like NCD3G PF07562.14 EKX34852.1 - 0.008 16.1 2.5 0.008 16.1 2.5 22.4 15 6 9 25 25 25 17 Nine Cysteines Domain of family 3 GPCR Phage_spike PF18715.1 EKX34852.1 - 0.061 13.4 0.1 0.22 11.6 0.1 2.0 1 0 0 1 1 1 0 Phage spike trimer DUF5530 PF17670.1 EKX34854.1 - 0.099 12.4 0.1 0.3 10.9 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5530) DUF5445 PF17520.2 EKX34854.1 - 0.9 9.4 4.4 0.38 10.6 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5445) OrfB_Zn_ribbon PF07282.11 EKX34857.1 - 5.3 7.0 5.9 1.9 8.5 1.3 2.4 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DUF2461 PF09365.10 EKX34858.1 - 0.095 12.6 0.1 0.52 10.2 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical protein (DUF2461) DUF2671 PF10877.8 EKX34860.1 - 0.12 12.2 0.2 0.27 11.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2671) Senescence_reg PF04520.13 EKX34863.1 - 0.015 16.2 2.5 0.018 15.9 2.5 1.0 1 0 0 1 1 1 0 Senescence regulator PDDEXK_3 PF13366.6 EKX34864.1 - 1.1e-08 35.5 0.0 2.8e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily YabA PF06156.13 EKX34864.1 - 6.4 7.5 9.4 0.81 10.4 1.3 2.8 2 0 0 2 2 2 0 Initiation control protein YabA LIX1 PF14954.6 EKX34866.1 - 0.062 12.6 0.1 0.096 12.0 0.1 1.2 1 0 0 1 1 1 0 Limb expression 1 PAP_RNA-bind PF04926.15 EKX34866.1 - 0.076 12.6 0.2 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain Ureide_permease PF07168.11 EKX34866.1 - 0.13 11.0 4.5 0.085 11.6 0.2 2.1 1 1 1 2 2 2 0 Ureide permease CDC45 PF02724.14 EKX34866.1 - 0.16 10.2 2.3 0.22 9.7 2.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Glycos_transf_4 PF00953.21 EKX34866.1 - 2.4 8.1 13.5 0.25 11.3 1.7 3.0 2 1 0 3 3 3 0 Glycosyl transferase family 4 SMBP PF16785.5 EKX34868.1 - 0.024 14.9 2.1 0.051 13.8 2.1 1.5 1 0 0 1 1 1 0 Small metal-binding protein UPF0767 PF15990.5 EKX34869.1 - 0.21 11.8 0.9 0.42 10.8 0.4 1.7 1 1 1 2 2 2 0 UPF0767 family Peptidase_S78 PF04586.17 EKX34870.1 - 0.005 17.0 0.0 0.0077 16.4 0.0 1.2 1 0 0 1 1 1 1 Caudovirus prohead serine protease T6SS_Vgr PF13296.6 EKX34870.1 - 0.041 14.0 0.0 0.092 12.9 0.0 1.5 1 0 0 1 1 1 0 Putative type VI secretion system Rhs element Vgr FTHFS PF01268.19 EKX34873.1 - 0.029 12.6 1.3 0.038 12.2 1.3 1.2 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase Syntaxin-6_N PF09177.11 EKX34873.1 - 0.073 13.6 7.2 0.16 12.6 3.3 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Proteasome PF00227.26 EKX34873.1 - 0.12 11.8 1.2 0.14 11.6 0.3 1.6 2 0 0 2 2 2 0 Proteasome subunit ArAE_2_N PF10337.9 EKX34873.1 - 0.35 9.8 5.9 0.073 12.1 1.1 1.9 1 1 1 2 2 2 0 Putative ER transporter, 6TM, N-terminal DEAD_2 PF06733.15 EKX34873.1 - 0.58 9.8 7.2 0.094 12.3 2.3 2.1 1 1 1 2 2 2 0 DEAD_2 APG6_N PF17675.1 EKX34873.1 - 0.9 10.1 19.4 0.4 11.2 8.4 2.5 1 1 0 2 2 2 0 Apg6 coiled-coil region Cnn_1N PF07989.11 EKX34873.1 - 1.3 9.2 12.9 1 9.5 7.5 2.6 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 FapA PF03961.13 EKX34873.1 - 1.4 7.4 11.8 2.1 6.8 11.8 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A DUF2630 PF10944.8 EKX34873.1 - 1.5 9.3 10.4 0.11 13.0 1.8 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2630) Prefoldin PF02996.17 EKX34873.1 - 10 6.1 14.7 7.7 6.5 0.9 2.6 1 1 0 2 2 2 0 Prefoldin subunit Snf7 PF03357.21 EKX34875.1 - 3.7e-15 56.0 7.4 5.6e-15 55.4 7.4 1.2 1 0 0 1 1 1 1 Snf7 HrpB_C PF08482.10 EKX34875.1 - 0.11 13.0 0.4 0.25 11.7 0.1 1.7 2 0 0 2 2 2 0 ATP-dependent helicase C-terminal AAA_18 PF13238.6 EKX34876.1 - 1.4e-08 35.3 0.1 1.8e-08 35.0 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EKX34876.1 - 0.00059 20.1 0.0 0.00072 19.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain P-mevalo_kinase PF04275.14 EKX34876.1 - 0.0045 16.9 1.3 0.014 15.3 0.6 2.1 2 1 0 2 2 2 1 Phosphomevalonate kinase AAA_17 PF13207.6 EKX34876.1 - 0.01 16.3 0.0 0.05 14.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EKX34876.1 - 0.019 14.2 1.0 0.07 12.3 1.0 1.8 1 1 0 1 1 1 0 NB-ARC domain dNK PF01712.19 EKX34876.1 - 0.019 14.8 0.0 0.057 13.3 0.0 1.7 1 1 0 2 2 2 0 Deoxynucleoside kinase AAA_33 PF13671.6 EKX34876.1 - 0.038 14.1 0.0 0.053 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain Sulf_coat_C PF12193.8 EKX34876.1 - 0.16 12.1 0.0 0.26 11.4 0.0 1.2 1 0 0 1 1 1 0 Sulfolobus virus coat protein C terminal CopD PF05425.13 EKX34877.1 - 0.035 14.5 0.2 0.053 13.9 0.2 1.2 1 0 0 1 1 1 0 Copper resistance protein D Stn1 PF10451.9 EKX34880.1 - 0.21 10.5 0.0 0.3 10.0 0.0 1.1 1 0 0 1 1 1 0 Telomere regulation protein Stn1 BIRC6 PF12356.8 EKX34883.1 - 0.017 14.6 0.1 0.025 14.0 0.1 1.1 1 0 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 DALR_1 PF05746.15 EKX34884.1 - 0.11 12.7 0.1 6.8 6.9 0.0 2.2 2 0 0 2 2 2 0 DALR anticodon binding domain CHGN PF05679.16 EKX34887.1 - 0.033 13.0 2.5 0.039 12.8 2.5 1.0 1 0 0 1 1 1 0 Chondroitin N-acetylgalactosaminyltransferase SWIRM-assoc_1 PF16495.5 EKX34887.1 - 0.12 12.3 4.7 1 9.3 0.4 2.3 2 0 0 2 2 2 0 SWIRM-associated region 1 DUF5320 PF17253.2 EKX34887.1 - 0.5 11.5 3.1 2.5 9.2 0.3 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5320) DcpS_C PF11969.8 EKX34888.1 - 1.4e-18 67.4 0.0 1.9e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF2711 PF10924.8 EKX34888.1 - 0.0055 16.3 0.0 0.013 15.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2711) TBP PF00352.21 EKX34893.1 - 2.8e-22 78.4 0.0 1.8e-13 50.3 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EKX34893.1 - 0.054 13.6 0.0 0.19 11.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3378) SAP18 PF06487.12 EKX34897.1 - 0.0032 17.7 0.4 0.035 14.3 0.0 2.5 2 0 0 2 2 2 1 Sin3 associated polypeptide p18 (SAP18) RNA_pol_Rpo13 PF12136.8 EKX34898.1 - 0.0032 17.3 0.2 0.008 16.1 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpo13 subunit HTH domain Ephrin_rec_like PF07699.13 EKX34899.1 - 1.6e-31 107.8 73.7 4e-08 32.9 5.6 6.6 5 1 2 7 7 7 6 Putative ephrin-receptor like DUF5012 PF16404.5 EKX34899.1 - 0.036 14.2 0.1 0.067 13.3 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5012) EGF_MSP1_1 PF12946.7 EKX34899.1 - 0.059 13.4 2.2 0.059 13.4 2.2 7.7 7 2 2 9 9 9 0 MSP1 EGF domain 1 NCD3G PF07562.14 EKX34899.1 - 0.14 12.1 57.5 0.077 13.0 3.6 7.2 4 2 2 7 7 6 0 Nine Cysteines Domain of family 3 GPCR GAD-like PF08887.11 EKX34899.1 - 0.29 10.9 0.7 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 GAD-like domain Heliorhodopsin PF18761.1 EKX34902.1 - 8.1e-14 51.5 11.8 1.2e-12 47.6 0.4 2.3 2 1 0 2 2 2 2 Heliorhodopsin PIG-P PF08510.12 EKX34903.1 - 8.1 6.4 8.3 41 4.1 1.0 3.5 3 0 0 3 3 3 0 PIG-P RNase_H_2 PF13482.6 EKX34905.1 - 4.4e-15 56.1 0.7 1.6e-13 51.0 0.1 2.0 2 0 0 2 2 2 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 EKX34905.1 - 1.1e-07 31.8 0.1 0.0019 17.9 0.0 2.3 1 1 1 2 2 2 2 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_A_exo1 PF01612.20 EKX34905.1 - 4.1e-05 23.4 0.0 5.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease DNA_pol_B_exo1 PF03104.19 EKX34905.1 - 0.013 14.6 0.0 0.07 12.2 0.0 2.0 2 0 0 2 2 2 0 DNA polymerase family B, exonuclease domain DUF5051 PF16473.5 EKX34905.1 - 0.017 15.1 0.0 1.3 8.9 0.0 2.1 1 1 1 2 2 2 0 3' exoribonuclease, RNase T-like Phage_Gp15 PF06854.11 EKX34906.1 - 0.021 14.8 2.0 0.049 13.6 1.1 2.1 2 0 0 2 2 2 0 Bacteriophage Gp15 protein BAMBI PF06211.12 EKX34907.1 - 0.0039 17.4 0.1 0.0081 16.4 0.1 1.4 1 0 0 1 1 1 1 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain zf-RING_2 PF13639.6 EKX34910.1 - 0.082 13.3 0.2 0.082 13.3 0.2 2.7 3 0 0 3 3 3 0 Ring finger domain zf-C3HC4_2 PF13923.6 EKX34910.1 - 9.5 6.2 9.4 0.26 11.2 0.6 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) AAA-ATPase_like PF09820.9 EKX34911.1 - 0.012 15.0 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Predicted AAA-ATPase HisKA PF00512.25 EKX34911.1 - 0.19 11.8 1.5 0.51 10.4 1.0 1.9 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain DUF1717 PF05414.11 EKX34912.1 - 0.065 13.7 0.0 0.19 12.2 0.0 1.8 1 0 0 1 1 1 0 Viral domain of unknown function (DUF1717) Peptidase_S64 PF08192.11 EKX34913.1 - 4.8 5.5 15.2 1.1 7.6 11.2 1.7 2 0 0 2 2 2 0 Peptidase family S64 ARF7EP_C PF14949.6 EKX34915.1 - 0.13 12.9 0.3 0.26 11.9 0.3 1.4 1 0 0 1 1 1 0 ARF7 effector protein C-terminus TNFR_c6 PF00020.18 EKX34916.1 - 0.0017 18.7 4.7 0.0017 18.7 4.7 11.4 7 2 5 12 12 12 4 TNFR/NGFR cysteine-rich region Ephrin_rec_like PF07699.13 EKX34916.1 - 0.0074 16.0 10.5 0.0074 16.0 10.5 9.5 9 3 1 10 10 10 2 Putative ephrin-receptor like RTA1 PF04479.13 EKX34916.1 - 0.022 14.4 4.5 0.053 13.1 4.5 1.6 1 1 0 1 1 1 0 RTA1 like protein Glucos_trans_II PF14264.6 EKX34916.1 - 0.12 11.8 5.8 0.095 12.0 3.4 1.8 2 0 0 2 2 2 0 Glucosyl transferase GtrII AAA_12 PF13087.6 EKX34918.1 - 0.00025 20.7 0.2 0.0005 19.8 0.2 1.4 1 1 0 1 1 1 1 AAA domain TraF_2 PF13729.6 EKX34918.1 - 0.2 11.0 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein MYCBPAP PF14646.6 EKX34919.1 - 4.8e-42 144.4 3.9 4.8e-42 144.4 3.9 1.7 1 1 0 1 1 1 1 MYCBP-associated protein family SRP_TPR_like PF17004.5 EKX34919.1 - 0.047 13.7 3.2 3.6 7.6 0.2 2.6 2 0 0 2 2 2 0 Putative TPR-like repeat RCC1 PF00415.18 EKX34920.1 - 4.9e-54 180.8 16.4 1.3e-08 35.3 0.0 8.9 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX34920.1 - 4.9e-31 105.9 39.4 1.4e-10 40.7 0.1 9.6 10 0 0 10 10 10 7 Regulator of chromosome condensation (RCC1) repeat Fn3_assoc PF13287.6 EKX34920.1 - 1e-09 38.4 0.1 2.4e-09 37.2 0.1 1.6 1 0 0 1 1 1 1 Fn3 associated CHB_HEX_C_1 PF13290.6 EKX34920.1 - 1.1e-09 38.1 0.0 2.6e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain LisH_2 PF16045.5 EKX34920.1 - 0.017 14.2 0.0 0.033 13.2 0.0 1.5 1 0 0 1 1 1 0 LisH Tudor_1_RapA PF18339.1 EKX34920.1 - 0.2 11.6 0.1 1 9.4 0.1 2.1 2 0 0 2 2 2 0 RapA N-terminal Tudor like domain 1 GREB1 PF15782.5 EKX34922.1 - 8.1e-30 102.9 23.3 2.9e-19 67.9 0.1 4.8 4 1 0 4 4 4 3 Gene regulated by oestrogen in breast cancer Peptidase_C14 PF00656.22 EKX34922.1 - 8.6e-10 39.0 0.0 8.6e-10 39.0 0.0 2.2 2 0 0 2 2 2 1 Caspase domain Coilin_N PF15862.5 EKX34922.1 - 0.63 9.8 12.1 2.4 8.0 12.1 2.0 1 0 0 1 1 1 0 Coilin N-terminus DUF908 PF06012.12 EKX34922.1 - 1.3 8.4 8.2 2.4 7.5 8.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DDHD PF02862.17 EKX34922.1 - 9.8 6.3 7.1 36 4.4 7.1 2.0 1 0 0 1 1 1 0 DDHD domain HTH_42 PF06224.12 EKX34925.1 - 0.0019 17.8 0.0 0.0021 17.7 0.0 1.1 1 0 0 1 1 1 1 Winged helix DNA-binding domain MarR PF01047.22 EKX34925.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 MarR family PDZ PF00595.24 EKX34926.1 - 4.8e-15 55.7 0.2 4.9e-07 30.0 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX34926.1 - 6e-13 48.9 0.4 6.5e-06 26.4 0.1 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EKX34926.1 - 2e-12 46.7 0.4 4.7e-07 29.5 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_4 PF17816.1 EKX34926.1 - 0.0077 16.6 0.0 0.022 15.2 0.0 1.8 1 0 0 1 1 1 1 PDZ domain ABC2_membrane PF01061.24 EKX34927.1 - 1.4e-60 204.3 51.1 7.5e-35 120.3 21.3 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EKX34927.1 - 2.2e-40 138.3 0.0 1.5e-22 80.6 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 EKX34927.1 - 7.5e-08 32.9 0.0 0.0029 18.0 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 EKX34927.1 - 7.2e-07 29.3 0.2 0.0027 17.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EKX34927.1 - 8.6e-07 29.3 0.1 0.0039 17.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EKX34927.1 - 1e-06 28.4 0.6 0.0045 16.7 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 EKX34927.1 - 1.8e-06 27.3 18.5 1.8e-06 27.3 18.5 2.3 2 0 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EKX34927.1 - 2.5e-06 27.5 0.1 0.0016 18.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase PDR_assoc PF08370.11 EKX34927.1 - 0.0001 21.9 0.0 0.0001 21.9 0.0 2.1 2 0 0 2 2 1 1 Plant PDR ABC transporter associated AAA_25 PF13481.6 EKX34927.1 - 0.00022 20.8 0.3 0.43 10.1 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EKX34927.1 - 0.00033 21.2 0.0 0.47 11.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EKX34927.1 - 0.00038 20.9 0.6 0.53 10.7 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EKX34927.1 - 0.00072 19.3 0.1 0.65 9.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EKX34927.1 - 0.0027 17.8 0.3 1.4 9.0 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase TsaE PF02367.17 EKX34927.1 - 0.0043 17.1 0.3 2.4 8.2 0.1 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 EKX34927.1 - 0.0043 16.8 1.6 1.9 8.2 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 EKX34927.1 - 0.0047 16.5 0.9 1.9 8.1 0.4 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EKX34927.1 - 0.0052 17.0 0.0 2.8 8.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EKX34927.1 - 0.0058 16.6 0.0 3.1 7.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.6 EKX34927.1 - 0.0068 16.9 1.2 0.35 11.3 0.3 2.3 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EKX34927.1 - 0.0076 16.0 1.3 1.1 8.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EKX34927.1 - 0.0088 16.1 0.1 0.39 10.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EKX34927.1 - 0.0094 16.3 0.1 2.3 8.7 0.0 2.8 2 0 0 2 2 2 1 RNA helicase ATPase_2 PF01637.18 EKX34927.1 - 0.012 15.5 0.0 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RuvB_N PF05496.12 EKX34927.1 - 0.014 15.2 0.4 1.3 8.8 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 EKX34927.1 - 0.015 15.2 1.4 0.48 10.3 0.0 2.8 3 0 0 3 3 3 0 NTPase Roc PF08477.13 EKX34927.1 - 0.016 15.4 0.2 5.3 7.3 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DnaB_C PF03796.15 EKX34927.1 - 0.016 14.6 0.0 0.15 11.4 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_19 PF13245.6 EKX34927.1 - 0.02 15.2 0.4 1.7 9.0 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.6 EKX34927.1 - 0.026 14.8 2.1 3.2 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 EKX34927.1 - 0.035 13.7 0.0 2.8 7.6 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SMC_N PF02463.19 EKX34927.1 - 0.064 12.7 0.1 6.4 6.2 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 EKX34927.1 - 0.17 11.2 0.1 9.4 5.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin Kinesin PF00225.23 EKX34930.1 - 2.5e-24 85.8 0.0 2.7e-24 85.7 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain GREB1 PF15782.5 EKX34931.1 - 1.9e-28 98.3 21.7 2.5e-17 61.5 0.1 4.8 4 1 0 4 4 4 3 Gene regulated by oestrogen in breast cancer Peptidase_C14 PF00656.22 EKX34931.1 - 3.9e-10 40.1 2.1 4.9e-10 39.8 0.0 2.1 2 0 0 2 2 2 1 Caspase domain DUF908 PF06012.12 EKX34931.1 - 0.3 10.5 6.0 0.62 9.4 6.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Spore_coat_CotO PF14153.6 EKX34931.1 - 3.3 7.6 15.6 13 5.6 15.6 2.0 1 0 0 1 1 1 0 Spore coat protein CotO ATG19_autophagy PF12744.7 EKX34932.1 - 0.096 11.9 0.3 0.14 11.3 0.3 1.2 1 0 0 1 1 1 0 Autophagy protein Atg19, Atg8-binding DUF2418 PF10332.9 EKX34932.1 - 1.9 9.1 3.8 1.8 9.1 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2418) DUF4692 PF15763.5 EKX34933.1 - 0.17 12.3 2.0 0.19 12.2 2.0 1.0 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) MatE PF01554.18 EKX34934.1 - 2.1e-13 50.2 22.7 1.3e-08 34.6 1.5 4.4 4 1 1 5 5 5 4 MatE Polysacc_synt_C PF14667.6 EKX34934.1 - 5.8e-08 32.9 5.7 5.8e-08 32.9 5.7 2.7 3 0 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain Zn_clus PF00172.18 EKX34935.1 - 8.8e-06 25.7 10.0 1.7e-05 24.9 10.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3293 PF11697.8 EKX34935.1 - 0.034 14.6 0.1 0.093 13.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3293) YscJ_FliF_C PF08345.11 EKX34936.1 - 0.074 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal Zip PF02535.22 EKX34937.1 - 1e-27 97.2 15.6 2.3e-26 92.8 15.6 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter YitT_membrane PF02588.15 EKX34937.1 - 0.023 14.1 0.3 0.023 14.1 0.3 2.1 2 0 0 2 2 2 0 Uncharacterised 5xTM membrane BCR, YitT family COG1284 DUF4223 PF13978.6 EKX34937.1 - 0.15 12.0 0.1 0.36 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) Zip PF02535.22 EKX34939.1 - 6.6e-22 78.2 12.6 3.7e-11 42.8 0.7 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter DUF4223 PF13978.6 EKX34939.1 - 0.11 12.4 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) Zip PF02535.22 EKX34940.1 - 2.3e-28 99.4 14.5 4.1e-27 95.3 14.5 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter YitT_membrane PF02588.15 EKX34940.1 - 0.023 14.1 0.3 0.023 14.1 0.3 2.2 2 0 0 2 2 2 0 Uncharacterised 5xTM membrane BCR, YitT family COG1284 DUF4223 PF13978.6 EKX34940.1 - 0.15 12.0 0.1 0.36 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) Glyco_hydro_9 PF00759.19 EKX34941.1 - 4.4e-30 105.4 0.4 6.3e-30 104.9 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Spectrin_like PF18373.1 EKX34943.1 - 0.18 11.9 1.1 0.36 10.9 0.1 2.0 2 1 1 3 3 3 0 Spectrin like domain DSPc PF00782.20 EKX34944.1 - 2e-31 108.6 0.1 2.7e-31 108.1 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX34944.1 - 8e-05 22.3 0.0 9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 EKX34944.1 - 0.012 15.8 0.1 0.02 15.2 0.1 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain CDKN3 PF05706.12 EKX34944.1 - 0.024 14.3 0.4 0.038 13.7 0.4 1.5 1 1 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Gelsolin PF00626.22 EKX34945.1 - 0.021 14.7 0.1 0.096 12.6 0.1 1.9 1 1 0 1 1 1 0 Gelsolin repeat Cytochrom_C550 PF14495.6 EKX34945.1 - 0.035 13.8 0.1 0.079 12.7 0.0 1.6 1 1 1 2 2 2 0 Cytochrome c-550 domain Hexapep PF00132.24 EKX34946.1 - 6.9e-06 25.6 4.3 0.087 12.6 1.4 3.3 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EKX34946.1 - 0.0084 15.8 4.8 0.23 11.3 0.1 3.0 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Ammonium_transp PF00909.21 EKX34947.1 - 8.4e-62 209.1 35.9 1.1e-39 136.4 12.4 2.2 1 1 1 2 2 2 2 Ammonium Transporter Family MscS_porin PF12795.7 EKX34947.1 - 0.031 13.8 9.9 0.041 13.4 9.9 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF16 PF01519.16 EKX34947.1 - 0.072 13.6 1.2 0.12 12.9 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 FemAB PF02388.16 EKX34947.1 - 0.095 11.6 0.1 0.14 11.0 0.1 1.2 1 0 0 1 1 1 0 FemAB family SlyX PF04102.12 EKX34947.1 - 0.22 12.2 6.1 0.38 11.4 6.1 1.4 1 0 0 1 1 1 0 SlyX DUF3450 PF11932.8 EKX34947.1 - 1.1 8.5 5.9 1.5 8.0 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FBPase PF00316.20 EKX34950.1 - 1.5e-49 168.0 2.9 3.2e-48 163.7 2.9 2.1 1 1 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Multi-haem_cyto PF13447.6 EKX34950.1 - 0.22 10.7 0.0 0.38 10.0 0.0 1.3 1 0 0 1 1 1 0 Seven times multi-haem cytochrome CxxCH Lactamase_B_2 PF12706.7 EKX34951.1 - 2.4e-14 53.3 0.1 5.6e-12 45.6 0.1 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EKX34951.1 - 3.9e-09 36.8 0.0 8.9e-09 35.6 0.0 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF2967 PF11179.8 EKX34952.1 - 1.8 6.5 6.5 2.2 6.3 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) AAA_12 PF13087.6 EKX34953.1 - 2.6e-52 177.4 0.0 2.9e-52 177.2 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EKX34953.1 - 2.8e-10 40.4 0.0 7.8e-10 39.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain Ldh_2 PF02615.14 EKX34954.1 - 6.3e-85 285.3 0.0 7.2e-85 285.1 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase PIG-U PF06728.13 EKX34956.1 - 6.2e-63 213.1 12.3 6.6e-63 213.0 12.3 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 EKX34956.1 - 0.05 13.3 14.8 0.075 12.7 14.8 1.3 1 0 0 1 1 1 0 8TM Microsporidial transmembrane domain MIR PF02815.19 EKX34956.1 - 0.22 11.4 0.0 0.32 10.8 0.0 1.2 1 0 0 1 1 1 0 MIR domain PsbX PF06596.11 EKX34958.1 - 0.014 15.3 0.3 0.031 14.3 0.3 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) DUF1418 PF07214.12 EKX34958.1 - 0.23 11.3 0.0 0.23 11.3 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1418) Glyco_tranf_2_3 PF13641.6 EKX34959.1 - 0.077 12.9 0.0 0.19 11.6 0.0 1.6 2 0 0 2 2 2 0 Glycosyltransferase like family 2 DUF563 PF04577.14 EKX34960.1 - 4.1e-35 121.8 0.0 5.3e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF4407 PF14362.6 EKX34961.1 - 0.72 9.1 2.9 1.7 7.9 2.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TGT PF01702.18 EKX34963.1 - 4.2e-31 108.4 0.0 1.1e-29 103.7 0.0 2.0 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase mTERF PF02536.14 EKX34964.1 - 2.2e-26 92.5 1.4 4.4e-18 65.3 1.0 2.0 2 0 0 2 2 2 2 mTERF UPF0137 PF03677.13 EKX34964.1 - 0.053 13.3 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) STPPase_N PF16891.5 EKX34964.1 - 0.57 10.7 3.1 3.3 8.2 0.1 2.8 3 0 0 3 3 3 0 Serine-threonine protein phosphatase N-terminal domain EF-hand_7 PF13499.6 EKX34966.1 - 9.2e-37 125.3 5.8 1.1e-12 48.2 0.1 4.6 4 1 0 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 EKX34966.1 - 1e-33 112.3 9.4 5e-07 28.8 0.2 7.7 7 1 1 8 8 8 6 EF hand EF-hand_6 PF13405.6 EKX34966.1 - 3e-28 95.3 10.3 1.7e-06 27.5 0.2 7.5 6 1 1 7 7 7 6 EF-hand domain EF-hand_8 PF13833.6 EKX34966.1 - 7.4e-25 86.6 16.1 1e-05 25.3 0.2 7.2 3 3 3 6 6 6 6 EF-hand domain pair EF-hand_5 PF13202.6 EKX34966.1 - 3.6e-21 73.6 13.8 0.0012 18.3 0.1 7.0 7 0 0 7 7 7 6 EF hand RIIa PF02197.17 EKX34966.1 - 3.9e-10 39.2 0.5 1.3e-09 37.6 0.5 1.9 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit SPARC_Ca_bdg PF10591.9 EKX34966.1 - 3.5e-09 37.0 2.9 0.027 14.8 0.0 3.4 3 0 0 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EKX34966.1 - 1e-07 31.8 10.0 0.026 14.5 0.1 5.7 2 1 4 6 6 6 3 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 EKX34966.1 - 7.6e-06 25.7 7.6 0.066 13.1 0.1 5.4 5 1 1 6 6 6 2 EF hand EF-hand_11 PF08976.11 EKX34966.1 - 0.00094 20.0 0.2 6.4 7.7 0.0 3.5 2 2 2 4 4 4 2 EF-hand domain DUF5580 PF17743.1 EKX34966.1 - 0.005 15.4 0.1 0.042 12.4 0.2 2.2 2 1 0 2 2 2 1 Family of unknown function (DUF5580) AAA_15 PF13175.6 EKX34966.1 - 0.081 12.6 4.7 0.12 12.1 4.7 1.3 1 0 0 1 1 1 0 AAA ATPase domain EF-hand_14 PF17959.1 EKX34966.1 - 0.28 11.6 5.5 0.53 10.7 0.0 3.8 3 2 2 5 5 5 0 EF-hand domain Eno-Rase_FAD_bd PF07055.12 EKX34966.1 - 5.7 7.4 6.3 1.1 9.8 1.1 2.5 2 0 0 2 2 2 0 Enoyl reductase FAD binding domain Lig_chan PF00060.26 EKX34967.1 - 2.4e-13 50.2 3.4 4.2e-13 49.4 0.4 2.5 2 1 0 2 2 2 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 EKX34967.1 - 0.0018 17.8 0.0 0.33 10.3 0.0 2.4 2 1 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 EKX34967.1 - 0.1 12.8 0.0 0.79 9.9 0.0 2.2 2 0 0 2 2 2 0 Ligated ion channel L-glutamate- and glycine-binding site FAM176 PF14851.6 EKX34967.1 - 0.14 11.9 0.6 1.3 8.7 0.1 2.3 2 0 0 2 2 2 0 FAM176 family LapA_dom PF06305.11 EKX34967.1 - 2.2 8.1 7.5 25 4.8 0.1 3.6 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Ank_2 PF12796.7 EKX34968.1 - 2.9e-14 53.4 0.2 4.1e-13 49.7 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX34968.1 - 4e-14 52.8 0.1 5.9e-12 45.9 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX34968.1 - 1.2e-10 41.4 0.2 4.6e-08 33.1 0.0 3.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 EKX34968.1 - 3e-10 40.1 0.8 1.3e-09 38.1 0.1 2.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX34968.1 - 3.5e-10 39.2 0.6 4.3e-05 23.6 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EKX34969.1 - 4.8e-13 49.0 0.2 3.3e-12 46.4 0.1 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX34969.1 - 1.1e-12 48.4 0.0 2.1e-12 47.5 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX34969.1 - 6.2e-11 42.6 0.0 2.9e-10 40.5 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX34969.1 - 1.8e-08 34.4 0.0 2.6e-07 30.8 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EKX34969.1 - 3.6e-07 30.0 0.0 1.6e-05 24.9 0.0 2.9 3 1 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EKX34970.1 - 2.7e-16 59.7 0.1 1e-07 32.3 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX34970.1 - 6.7e-14 52.2 0.2 5.6e-13 49.3 0.2 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX34970.1 - 1.2e-11 44.6 0.8 5.5e-06 26.6 0.0 2.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX34970.1 - 6.2e-08 32.3 0.1 0.00021 21.5 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EKX34970.1 - 3.7e-07 30.3 1.0 8.4e-06 26.0 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EKX34971.1 - 9.6e-19 67.5 0.3 1.3e-11 44.8 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX34971.1 - 1.1e-15 58.0 0.3 4.9e-15 55.9 0.3 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX34971.1 - 1.4e-15 57.1 0.6 2.7e-13 49.9 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX34971.1 - 2.1e-15 56.4 0.7 1.8e-08 34.5 0.0 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EKX34971.1 - 6.8e-14 50.6 0.3 1.7e-07 31.0 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ion_trans PF00520.31 EKX34972.1 - 2.7e-27 95.6 13.2 2.7e-27 95.6 13.2 2.5 2 1 0 2 2 2 1 Ion transport protein EF-hand_1 PF00036.32 EKX34972.1 - 0.0011 18.4 0.1 0.0059 16.1 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EKX34972.1 - 0.018 14.9 0.1 0.32 11.0 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain Orf78 PF06024.12 EKX34972.1 - 0.032 14.5 8.3 0.034 14.5 3.3 2.7 2 0 0 2 2 2 0 Orf78 (ac78) EF-hand_7 PF13499.6 EKX34972.1 - 0.033 14.6 0.0 0.12 12.8 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair Mac_assoc PF16628.5 EKX34973.1 - 0.096 12.9 6.2 0.1 12.8 1.2 2.1 1 1 1 2 2 2 0 Unstructured region on maltose acetyltransferase FXMR_C2 PF16098.5 EKX34974.1 - 0.02 15.4 3.8 0.038 14.5 3.6 1.6 1 1 0 1 1 1 0 Fragile X-related mental retardation protein C-terminal region 2 Hid1 PF12722.7 EKX34974.1 - 0.78 7.8 6.8 0.88 7.6 6.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Thioredoxin PF00085.20 EKX34975.1 - 3.5e-16 59.1 0.0 4.9e-16 58.6 0.0 1.2 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EKX34975.1 - 0.0042 17.4 0.0 0.015 15.6 0.0 1.7 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.6 EKX34975.1 - 0.029 14.5 0.0 0.042 14.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.6 EKX34975.1 - 0.059 13.8 0.0 0.13 12.7 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain Evr1_Alr PF04777.13 EKX34976.1 - 2.5e-19 69.6 0.0 2.7e-19 69.5 0.0 1.0 1 0 0 1 1 1 1 Erv1 / Alr family AraC_binding_2 PF14525.6 EKX34976.1 - 0.071 12.8 0.1 0.11 12.2 0.1 1.4 1 1 0 1 1 1 0 AraC-binding-like domain Pox_E10 PF04805.12 EKX34976.1 - 0.17 11.8 0.0 0.28 11.0 0.0 1.4 2 0 0 2 2 2 0 E10-like protein conserved region TPT PF03151.16 EKX34977.1 - 2.5e-83 279.8 16.3 3.5e-83 279.3 16.3 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EKX34977.1 - 6e-12 45.9 28.0 6e-08 32.9 8.8 2.4 2 0 0 2 2 2 2 EamA-like transporter family Nramp PF01566.18 EKX34978.1 - 2.1e-121 405.2 24.9 2.5e-121 405.0 24.9 1.0 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein DUF1270 PF06900.11 EKX34978.1 - 0.066 13.6 2.2 0.61 10.5 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1270) ANAPC4_WD40 PF12894.7 EKX34979.1 - 5.3e-09 36.3 0.1 0.011 16.0 0.0 5.6 5 1 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EKX34979.1 - 6.6e-06 26.8 3.2 0.23 12.4 0.0 5.5 4 0 0 4 4 4 1 WD domain, G-beta repeat Nbas_N PF15492.6 EKX34979.1 - 0.0032 16.9 0.0 0.022 14.1 0.0 2.3 2 1 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Clathrin PF00637.20 EKX34979.1 - 0.009 15.9 5.8 1.4 8.8 0.2 3.8 3 1 1 4 4 4 1 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 EKX34979.1 - 0.014 14.5 0.3 0.05 12.6 0.1 2.1 2 0 0 2 2 2 0 Coatomer WD associated region Trehalose_recp PF06151.13 EKX34979.1 - 0.021 13.5 0.1 0.036 12.7 0.1 1.3 1 0 0 1 1 1 0 Trehalose receptor Vps39_1 PF10366.9 EKX34979.1 - 0.1 12.9 0.1 0.28 11.5 0.1 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 TPR_7 PF13176.6 EKX34979.1 - 0.12 12.5 2.8 13 6.1 0.1 4.8 5 1 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX34979.1 - 0.2 11.9 9.3 12 6.2 0.0 5.1 4 2 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 EKX34979.1 - 1.4 9.3 3.6 13 6.3 0.2 4.3 6 0 0 6 6 6 0 PPR repeat RAMP4 PF06624.12 EKX34982.1 - 3.6e-20 71.8 1.7 4e-20 71.6 1.7 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 TSC22 PF01166.18 EKX34983.1 - 0.58 10.5 6.2 0.84 10.0 1.6 3.9 3 0 0 3 3 3 0 TSC-22/dip/bun family PKcGMP_CC PF16808.5 EKX34983.1 - 8.3 6.4 9.5 0.5 10.3 1.6 3.2 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Myosin_head PF00063.21 EKX34985.1 - 3.5e-226 752.6 0.9 4.1e-226 752.4 0.9 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 EKX34985.1 - 0.0037 17.5 0.0 0.018 15.4 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EKX34985.1 - 0.015 15.6 0.1 0.36 11.2 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EKX34985.1 - 0.024 15.0 0.0 0.13 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 EKX34985.1 - 0.03 14.1 0.1 3.5 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EKX34985.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Ank_2 PF12796.7 EKX34986.1 - 0.0063 17.1 0.0 0.33 11.6 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) HD PF01966.22 EKX34986.1 - 0.026 14.8 2.2 0.14 12.4 0.1 2.7 2 1 1 3 3 3 0 HD domain DUF1677 PF07911.13 EKX34986.1 - 0.047 14.1 0.4 0.21 12.0 0.4 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) Ank_3 PF13606.6 EKX34986.1 - 0.085 13.5 0.1 48 5.0 0.0 3.5 4 0 0 4 4 4 0 Ankyrin repeat HemY_N PF07219.13 EKX34986.1 - 0.78 10.0 4.3 12 6.2 0.2 2.4 2 0 0 2 2 2 0 HemY protein N-terminus dCMP_cyt_deam_1 PF00383.23 EKX34987.1 - 1.1e-24 86.2 0.2 1.5e-24 85.8 0.2 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EKX34987.1 - 3.3e-18 65.8 0.0 4.1e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 EKX34987.1 - 0.041 13.9 0.1 0.064 13.3 0.1 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase SNAD4 PF18750.1 EKX34987.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.5 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 EKX34987.1 - 0.18 12.0 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 APOBEC3 CPP1-like PF11833.8 EKX34988.1 - 0.004 16.9 1.4 0.004 16.9 1.4 2.6 1 1 0 2 2 2 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Ammonium_transp PF00909.21 EKX34990.1 - 5.2e-35 120.9 17.0 5.2e-35 120.9 17.0 1.7 2 0 0 2 2 2 1 Ammonium Transporter Family CDC14 PF08045.11 EKX34991.1 - 0.0014 17.8 1.6 0.0022 17.1 1.6 1.4 1 0 0 1 1 1 1 Cell division control protein 14, SIN component DUF383 PF04063.14 EKX34991.1 - 0.16 11.6 4.2 2.1 8.0 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF383) AAA_PrkA PF08298.11 EKX34992.1 - 0.17 10.7 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain RTT107_BRCT_5 PF16770.5 EKX34993.1 - 1.1e-05 25.3 0.0 1.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 EKX34993.1 - 9.8e-05 22.7 0.1 0.0015 18.8 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EKX34993.1 - 0.00047 20.5 0.0 0.029 14.8 0.0 2.5 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Rhodanese PF00581.20 EKX34994.1 - 3.9e-18 65.9 0.0 4.9e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DDE_Tnp_1_7 PF13843.6 EKX34995.1 - 4e-21 75.7 0.0 5.7e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 Aa_trans PF01490.18 EKX34997.1 - 8.6e-32 110.3 20.4 8.6e-32 110.3 20.4 1.9 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Trp_oprn_chp PF09534.10 EKX34997.1 - 9.8 5.9 11.5 0.47 10.2 3.2 2.5 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Mac_assoc PF16628.5 EKX34998.1 - 0.058 13.6 0.3 0.087 13.0 0.3 1.3 1 0 0 1 1 1 0 Unstructured region on maltose acetyltransferase Mac_assoc PF16628.5 EKX34999.1 - 0.081 13.1 0.2 0.12 12.5 0.2 1.3 1 0 0 1 1 1 0 Unstructured region on maltose acetyltransferase Mac_assoc PF16628.5 EKX35000.1 - 0.051 13.8 0.2 0.075 13.2 0.2 1.3 1 0 0 1 1 1 0 Unstructured region on maltose acetyltransferase LPP PF04728.13 EKX35001.1 - 0.14 12.6 3.6 1.6 9.2 0.1 3.1 2 1 0 2 2 2 0 Lipoprotein leucine-zipper Speriolin_N PF15058.6 EKX35001.1 - 0.19 11.8 3.4 0.083 13.0 0.7 1.8 2 0 0 2 2 2 0 Speriolin N terminus DUF4140 PF13600.6 EKX35001.1 - 1.6 9.2 13.9 0.6 10.6 1.3 3.6 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) ADIP PF11559.8 EKX35001.1 - 1.9 8.5 19.6 0.2 11.7 4.5 2.9 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF16 PF01519.16 EKX35001.1 - 2.7 8.5 9.6 3.7 8.1 2.1 2.7 2 1 0 2 2 2 0 Protein of unknown function DUF16 Bac_rhodopsin PF01036.18 EKX35002.1 - 7.2e-13 48.6 15.5 1.1e-12 48.0 15.5 1.3 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein ATPgrasp_ST PF14397.6 EKX35003.1 - 0.025 13.9 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EKX35003.1 - 0.046 13.8 0.0 0.4 10.7 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain GSH-S_ATP PF02955.16 EKX35003.1 - 0.12 11.8 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain PH PF00169.29 EKX35005.1 - 6.4e-05 23.4 0.2 0.00019 21.9 0.2 1.9 1 0 0 1 1 1 1 PH domain Mcp5_PH PF12814.7 EKX35005.1 - 0.0031 17.6 0.0 0.0084 16.2 0.0 1.8 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH_9 PF15410.6 EKX35005.1 - 0.052 13.9 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain PH_8 PF15409.6 EKX35005.1 - 0.13 12.5 0.0 0.37 11.1 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain NOA36 PF06524.12 EKX35005.1 - 6.6 6.0 24.6 1.3 8.2 1.5 3.5 3 0 0 3 3 3 0 NOA36 protein Methyltransf_16 PF10294.9 EKX35010.1 - 2.8e-15 56.5 0.0 6.6e-14 52.0 0.0 2.0 1 1 0 1 1 1 1 Lysine methyltransferase GidB PF02527.15 EKX35010.1 - 0.029 13.7 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G MTS PF05175.14 EKX35010.1 - 0.042 13.4 0.0 0.19 11.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_25 PF13649.6 EKX35010.1 - 0.043 14.5 0.1 11 6.8 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain Septin PF00735.18 EKX35011.1 - 2.6e-32 112.2 0.0 3.2e-32 111.9 0.0 1.0 1 0 0 1 1 1 1 Septin AAA_22 PF13401.6 EKX35011.1 - 6.5e-05 23.2 0.0 0.00012 22.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EKX35011.1 - 0.00051 20.1 0.0 0.00057 19.9 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EKX35011.1 - 0.0025 17.4 0.3 0.029 13.9 0.1 2.4 1 1 2 3 3 3 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EKX35011.1 - 0.0046 17.4 0.1 0.0086 16.5 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain Roc PF08477.13 EKX35011.1 - 0.0046 17.2 0.0 0.0082 16.3 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 EKX35011.1 - 0.012 16.2 0.0 0.019 15.5 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Ras PF00071.22 EKX35011.1 - 0.015 14.9 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Ras family AAA_24 PF13479.6 EKX35011.1 - 0.038 13.7 0.2 0.051 13.3 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EKX35011.1 - 0.093 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TyeA PF09059.10 EKX35011.1 - 0.096 12.8 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 TyeA ATP_bind_1 PF03029.17 EKX35011.1 - 0.16 11.7 0.0 7.5 6.2 0.0 2.8 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 EKX35011.1 - 0.22 11.4 0.8 1.2 9.1 0.3 2.3 2 1 0 2 2 2 0 RsgA GTPase Bac_rhodopsin PF01036.18 EKX35013.1 - 4.2e-15 55.9 15.2 6.7e-15 55.3 15.2 1.3 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Ion_trans_2 PF07885.16 EKX35013.1 - 0.38 10.8 6.7 0.17 11.9 2.2 2.5 2 0 0 2 2 2 0 Ion channel TIG PF01833.24 EKX35015.1 - 1.4e-80 265.4 97.7 7.5e-10 38.7 0.7 21.4 21 0 0 21 21 21 20 IPT/TIG domain TIG_plexin PF17960.1 EKX35015.1 - 8.6e-13 48.1 10.4 2.7 8.0 0.0 10.6 11 0 0 11 11 11 6 TIG domain Myco_19_kDa PF05481.12 EKX35015.1 - 0.00032 20.9 5.6 9.2 6.6 0.0 5.3 5 0 0 5 5 5 3 Mycobacterium 19 kDa lipoprotein antigen RHD_dimer PF16179.5 EKX35015.1 - 0.0065 16.5 0.0 16 5.6 0.0 4.0 5 0 0 5 5 5 2 Rel homology dimerisation domain TIG PF01833.24 EKX35016.1 - 5e-48 161.1 27.6 1.1e-10 41.4 0.2 9.6 9 0 0 9 9 9 8 IPT/TIG domain TIG_plexin PF17960.1 EKX35016.1 - 8.4e-07 28.9 4.4 40 4.3 0.0 7.7 7 0 0 7 7 7 0 TIG domain Ephrin_rec_like PF07699.13 EKX35016.1 - 0.00011 21.9 13.0 0.0014 18.4 6.6 12.0 8 4 5 13 13 13 5 Putative ephrin-receptor like Anth_Ig PF05587.13 EKX35016.1 - 0.006 16.9 0.5 9.4 6.6 0.0 4.7 4 0 0 4 4 4 1 Anthrax receptor extracellular domain GPR_Gpa2_C PF11970.8 EKX35016.1 - 0.0092 16.0 0.9 0.038 14.1 0.9 2.1 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term STIMATE PF12400.8 EKX35017.1 - 1.4e-32 112.9 6.7 2.7e-32 111.9 6.7 1.5 1 0 0 1 1 1 1 STIMATE family DUF3611 PF12263.8 EKX35017.1 - 0.053 13.4 1.7 0.097 12.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) RRM_1 PF00076.22 EKX35018.1 - 5.1e-20 71.1 0.0 9.6e-20 70.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.8 EKX35018.1 - 2.9e-15 56.8 1.0 5.2e-15 56.0 1.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G SHOCT PF09851.9 EKX35018.1 - 6.2e-07 29.0 0.0 1.2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Short C-terminal domain RRM_3 PF08777.11 EKX35018.1 - 0.002 18.1 0.0 0.005 16.9 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.6 EKX35018.1 - 0.0053 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif WD40 PF00400.32 EKX35019.1 - 0.00074 20.3 7.5 0.22 12.5 0.3 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat DEAD PF00270.29 EKX35020.1 - 7.1e-37 126.9 0.0 1.4e-36 125.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX35020.1 - 6e-25 87.7 0.0 3.6e-24 85.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX35020.1 - 0.00024 21.2 0.5 0.00091 19.3 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EKX35020.1 - 0.017 14.4 0.0 0.017 14.4 0.0 1.9 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 EKX35020.1 - 0.018 15.3 0.1 1.1 9.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF4217 PF13959.6 EKX35020.1 - 0.032 14.5 0.0 0.3 11.3 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4217) DBINO PF13892.6 EKX35020.1 - 0.34 11.3 19.9 0.95 9.8 19.9 1.8 1 0 0 1 1 1 0 DNA-binding domain ABC_tran_Xtn PF12848.7 EKX35020.1 - 2.7 8.1 17.3 10 6.2 17.3 2.0 1 0 0 1 1 1 0 ABC transporter CDC45 PF02724.14 EKX35020.1 - 9.1 4.4 11.1 13 3.9 11.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Zn_clus PF00172.18 EKX35021.1 - 3.2e-06 27.2 14.5 4.8e-06 26.6 14.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 EKX35022.1 - 2e-10 40.6 29.8 9.4e-06 25.7 14.5 2.2 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain CdiI_3 PF18616.1 EKX35025.1 - 0.035 14.0 0.0 0.048 13.5 0.0 1.2 1 0 0 1 1 1 0 CDI immunity proteins VSG_B PF13206.6 EKX35027.1 - 0.55 9.4 0.0 0.55 9.4 0.0 2.3 2 0 0 2 2 2 0 Trypanosomal VSG domain Elf4 PF07011.11 EKX35028.1 - 0.053 13.4 1.0 15 5.6 0.0 3.1 3 0 0 3 3 3 0 Early Flowering 4 domain Lipoprotein_2 PF00921.17 EKX35028.1 - 0.1 12.1 4.9 0.029 13.9 1.9 1.6 2 0 0 2 2 2 0 Borrelia lipoprotein DUF5589 PF17672.1 EKX35030.1 - 0.094 12.7 0.2 0.094 12.7 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5589) Tub_N PF16322.5 EKX35031.1 - 0.0082 16.6 8.1 1.1 9.7 0.0 2.7 2 0 0 2 2 2 1 Tubby N-terminal BSP_II PF05432.11 EKX35031.1 - 0.1 12.3 18.9 0.16 11.7 18.9 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Myc_N PF01056.18 EKX35031.1 - 0.36 10.7 14.5 0.12 12.3 7.0 2.4 2 0 0 2 2 2 0 Myc amino-terminal region PI3K_1B_p101 PF10486.9 EKX35031.1 - 2.4 5.8 6.6 4.1 5.1 6.6 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Na_trans_assoc PF06512.13 EKX35031.1 - 7.9 6.7 14.1 0.48 10.7 8.3 2.0 2 0 0 2 2 2 0 Sodium ion transport-associated NDC10_II PF16787.5 EKX35032.1 - 0.11 11.6 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Ank_4 PF13637.6 EKX35034.1 - 2.7e-10 40.6 0.1 0.0018 18.8 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX35034.1 - 2.6e-08 34.3 0.0 0.00016 22.2 0.0 2.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX35034.1 - 6.6e-07 29.5 0.0 0.0031 17.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PP-binding PF00550.25 EKX35034.1 - 7.9e-06 26.1 0.0 2.8e-05 24.4 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ank_3 PF13606.6 EKX35034.1 - 0.00025 21.3 0.0 0.36 11.5 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 EKX35034.1 - 0.012 16.1 0.0 8 7.1 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat Ribosomal_60s PF00428.19 EKX35034.1 - 0.42 11.2 12.1 0.24 12.0 0.2 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Keratin_2_head PF16208.5 EKX35034.1 - 1.9 8.6 11.7 4.5 7.4 11.7 1.5 1 0 0 1 1 1 0 Keratin type II head Ribonuc_red_lgC PF02867.15 EKX35035.1 - 0.0066 15.0 0.0 0.011 14.4 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain IQ PF00612.27 EKX35035.1 - 0.0084 15.8 0.2 0.0084 15.8 0.2 2.0 2 0 0 2 2 2 1 IQ calmodulin-binding motif BLOC1S3 PF15753.5 EKX35035.1 - 0.017 15.3 1.2 0.017 15.3 1.2 1.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 PseudoU_synth_1 PF01416.20 EKX35035.1 - 0.021 15.3 0.1 0.075 13.5 0.1 1.9 2 1 0 2 2 2 0 tRNA pseudouridine synthase SlyX PF04102.12 EKX35036.1 - 0.0078 16.8 4.5 0.0078 16.8 4.5 7.5 2 2 6 8 8 8 1 SlyX CENP-F_leu_zip PF10473.9 EKX35036.1 - 1.9 8.5 83.5 3.6 7.6 19.0 5.0 1 1 4 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3450 PF11932.8 EKX35036.1 - 8.6 5.6 67.1 0.018 14.4 11.3 5.5 1 1 5 6 6 6 0 Protein of unknown function (DUF3450) AAA_2 PF07724.14 EKX35037.1 - 6.9e-15 55.6 0.0 9.4e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EKX35037.1 - 1.5e-05 25.0 0.0 9.9e-05 22.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EKX35037.1 - 3.3e-05 24.2 0.1 0.00033 20.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EKX35037.1 - 4.6e-05 23.9 0.0 9.4e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX35037.1 - 0.00068 20.1 0.2 0.0034 17.8 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 EKX35037.1 - 0.0019 17.6 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Torsin PF06309.11 EKX35037.1 - 0.0041 17.2 0.0 0.017 15.2 0.0 1.9 2 0 0 2 2 2 1 Torsin RNA_helicase PF00910.22 EKX35037.1 - 0.0054 17.1 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 EKX35037.1 - 0.0055 16.9 0.0 0.013 15.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EKX35037.1 - 0.0079 16.1 0.0 0.021 14.8 0.0 1.7 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EKX35037.1 - 0.0086 15.8 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EKX35037.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.6 EKX35037.1 - 0.05 13.9 0.0 0.16 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EKX35037.1 - 0.055 14.0 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 EKX35037.1 - 0.088 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NACHT PF05729.12 EKX35037.1 - 0.11 12.5 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_6 PF12774.7 EKX35037.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region SRP54 PF00448.22 EKX35037.1 - 0.21 11.2 0.0 0.41 10.2 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PhoH PF02562.16 EKX35037.1 - 0.21 11.0 0.0 0.4 10.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein betaPIX_CC PF16523.5 EKX35038.1 - 0.19 11.6 0.9 11 5.9 0.2 2.4 2 0 0 2 2 2 0 betaPIX coiled coil KASH_CCD PF14662.6 EKX35039.1 - 0.0042 16.9 18.2 0.0042 16.9 18.2 5.0 3 1 1 4 4 4 2 Coiled-coil region of CCDC155 or KASH FAA_hydro_N_2 PF18288.1 EKX35039.1 - 1.4 9.4 4.6 16 6.0 0.1 4.1 3 1 0 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 Baculo_PEP_C PF04513.12 EKX35039.1 - 1.6 8.7 15.8 12 5.9 6.4 5.0 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 EKX35039.1 - 4.4 7.6 23.7 1.5 9.1 0.9 7.0 6 3 2 8 8 8 0 Bacterial protein of unknown function (DUF948) SSP160 PF06933.11 EKX35040.1 - 0.25 9.5 7.4 0.36 9.0 7.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MCM_bind PF09739.9 EKX35041.1 - 2.3e-33 115.5 0.2 3.1e-28 98.6 0.1 2.0 2 0 0 2 2 2 2 Mini-chromosome maintenance replisome factor DER1 PF04511.15 EKX35042.1 - 1.4e-30 106.6 10.0 2.2e-30 106.0 10.0 1.3 1 1 0 1 1 1 1 Der1-like family WW PF00397.26 EKX35045.1 - 7.4e-14 51.5 2.2 1.7e-13 50.4 2.2 1.7 1 0 0 1 1 1 1 WW domain KH_1 PF00013.29 EKX35045.1 - 1.2e-06 28.2 0.1 3.3e-05 23.6 0.0 2.9 3 0 0 3 3 3 1 KH domain cNMP_binding PF00027.29 EKX35046.1 - 8.6e-15 54.6 0.0 2.1e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 EKX35046.1 - 5.5e-09 35.6 7.6 8.5e-09 35.0 7.6 1.2 1 0 0 1 1 1 1 Ion transport protein Proteasome PF00227.26 EKX35047.1 - 9.7e-62 207.8 0.1 1.2e-61 207.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EKX35047.1 - 5.8e-14 51.4 0.0 1.2e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RWP-RK PF02042.15 EKX35048.1 - 4.5e-18 65.0 0.1 1.1e-17 63.7 0.1 1.7 1 0 0 1 1 1 1 RWP-RK domain DUF2274 PF10038.9 EKX35048.1 - 0.044 14.2 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2274) Tetraspanin PF00335.20 EKX35049.1 - 9.4e-07 28.8 13.7 5.8e-06 26.2 13.7 1.9 1 1 0 1 1 1 1 Tetraspanin family Claudin_2 PF13903.6 EKX35049.1 - 0.00082 19.2 2.3 0.031 14.0 0.1 2.2 1 1 1 2 2 2 2 PMP-22/EMP/MP20/Claudin tight junction DUF4271 PF14093.6 EKX35049.1 - 0.011 15.7 5.0 1.1 9.1 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) AgrB PF04647.15 EKX35049.1 - 0.039 13.3 5.9 0.05 12.9 4.7 1.7 1 1 1 2 2 2 0 Accessory gene regulator B DUF1736 PF08409.11 EKX35049.1 - 0.06 13.3 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1736) DUF2207 PF09972.9 EKX35049.1 - 0.43 9.3 5.1 7.7 5.2 0.5 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DHHC PF01529.20 EKX35049.1 - 0.87 9.7 9.2 9.5 6.3 1.1 2.1 1 1 1 2 2 2 0 DHHC palmitoyltransferase DUF4293 PF14126.6 EKX35049.1 - 1 9.6 5.0 5.2 7.3 5.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) MlaE PF02405.16 EKX35049.1 - 6.6 6.3 11.5 10 5.7 6.5 2.5 2 1 0 2 2 2 0 Permease MlaE MTS PF05175.14 EKX35051.1 - 1.9e-16 60.1 1.1 3.9e-12 46.1 0.5 3.1 2 1 0 2 2 2 2 Methyltransferase small domain PrmA PF06325.13 EKX35051.1 - 8.3e-13 48.4 0.0 1.3e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EKX35051.1 - 9.7e-10 39.0 0.0 2.9e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX35051.1 - 9.9e-10 38.4 0.0 1.9e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 EKX35051.1 - 3.1e-08 33.4 0.0 6e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 EKX35051.1 - 2e-06 27.7 0.0 5e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_23 PF13489.6 EKX35051.1 - 1.7e-05 24.7 0.0 0.00014 21.7 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EKX35051.1 - 2.6e-05 23.9 0.0 6.2e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Conserved hypothetical protein 95 N6_Mtase PF02384.16 EKX35051.1 - 0.0001 21.7 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_11 PF08241.12 EKX35051.1 - 0.00014 22.4 0.3 0.00036 21.1 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain UPF0020 PF01170.18 EKX35051.1 - 0.00058 19.6 0.1 0.0074 16.0 0.1 2.6 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_16 PF10294.9 EKX35051.1 - 0.0011 18.8 0.0 0.0031 17.3 0.0 1.7 2 0 0 2 2 2 1 Lysine methyltransferase Methyltr_RsmB-F PF01189.17 EKX35051.1 - 0.0035 17.0 0.0 0.0061 16.2 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F RrnaAD PF00398.20 EKX35051.1 - 0.0047 16.0 0.0 0.0077 15.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.18 EKX35051.1 - 0.0084 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TRM PF02005.16 EKX35051.1 - 0.009 15.2 0.0 0.025 13.8 0.0 1.7 2 0 0 2 2 2 1 N2,N2-dimethylguanosine tRNA methyltransferase tRNA_U5-meth_tr PF05958.11 EKX35051.1 - 0.01 14.9 0.0 0.014 14.4 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_12 PF08242.12 EKX35051.1 - 0.031 15.0 0.0 0.1 13.3 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain AviRa PF11599.8 EKX35051.1 - 0.046 13.2 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa CMAS PF02353.20 EKX35051.1 - 0.077 12.3 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RHSP PF07999.11 EKX35052.1 - 0.074 11.8 0.0 0.087 11.6 0.0 1.2 1 0 0 1 1 1 0 Retrotransposon hot spot protein RuvB_N PF05496.12 EKX35052.1 - 0.1 12.3 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain GST_N_3 PF13417.6 EKX35055.1 - 2.8e-07 30.9 0.0 6.9e-07 29.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EKX35055.1 - 0.05 13.9 0.0 0.081 13.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Ion_trans PF00520.31 EKX35056.1 - 1e-168 558.7 61.2 2.7e-56 190.6 8.7 5.1 5 0 0 5 5 5 5 Ion transport protein EF-hand_1 PF00036.32 EKX35056.1 - 1.3e-10 40.0 0.1 0.00011 21.5 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX35056.1 - 4.9e-09 36.5 1.3 1.4e-08 35.1 1.3 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX35056.1 - 8e-09 34.7 0.5 0.0015 18.3 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EKX35056.1 - 1.9e-08 34.0 0.1 5.3e-08 32.6 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX35056.1 - 3.3e-06 26.3 0.1 0.0043 16.5 0.1 2.7 2 0 0 2 2 2 2 EF hand EMP70 PF02990.16 EKX35056.1 - 0.0018 17.1 6.2 0.0018 17.1 6.2 2.6 2 0 0 2 2 2 1 Endomembrane protein 70 PKD_channel PF08016.12 EKX35056.1 - 0.0028 16.4 0.2 0.0028 16.4 0.2 9.7 9 2 2 11 11 11 6 Polycystin cation channel LodA_C PF18417.1 EKX35056.1 - 0.28 10.9 0.9 1.4 8.6 0.3 2.2 2 0 0 2 2 2 0 L-lysine epsilon oxidase C-terminal domain Pkinase PF00069.25 EKX35058.1 - 9.5e-63 212.0 0.0 1.2e-62 211.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX35058.1 - 5.3e-30 104.6 0.0 7.3e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX35058.1 - 0.00055 19.3 0.0 0.00095 18.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EKX35058.1 - 0.01 14.8 0.1 0.021 13.8 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 EKX35058.1 - 0.024 14.6 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EKX35058.1 - 0.047 13.0 0.1 0.078 12.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF166 PF02593.14 EKX35059.1 - 0.0053 16.3 0.0 0.0087 15.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function Arm PF00514.23 EKX35059.1 - 0.13 12.3 6.4 0.47 10.6 0.0 3.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat SipA_VBS PF17985.1 EKX35059.1 - 0.52 10.3 0.0 0.52 10.3 0.0 3.0 3 0 0 3 3 3 0 SipA vinculin binding site HEAT_EZ PF13513.6 EKX35059.1 - 0.53 10.9 4.5 1.3 9.6 0.1 3.1 3 0 0 3 3 3 0 HEAT-like repeat WD40 PF00400.32 EKX35061.1 - 6.2e-07 30.0 11.9 0.0041 17.9 0.2 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX35061.1 - 0.00044 20.5 0.0 5.1 7.5 0.0 4.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PBP1_TM PF14812.6 EKX35061.1 - 8 6.9 13.6 0.64 10.4 3.5 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sedlin_N PF04628.13 EKX35062.1 - 1e-44 151.8 0.3 1.2e-44 151.6 0.3 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EKX35062.1 - 2.5e-06 27.5 0.0 4.7e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Sybindin-like family DUF508 PF04370.12 EKX35062.1 - 0.088 12.6 0.1 0.093 12.5 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF508) Thioredoxin PF00085.20 EKX35063.1 - 1.7e-18 66.5 0.0 1.9e-18 66.4 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EKX35063.1 - 1e-08 35.6 0.1 4.8e-08 33.4 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EKX35063.1 - 0.00027 21.2 0.5 0.051 13.9 0.1 2.0 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 EKX35063.1 - 0.00044 19.7 0.1 0.00049 19.5 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 EKX35063.1 - 0.0021 18.1 0.1 0.0028 17.7 0.1 1.3 1 1 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.21 EKX35063.1 - 0.0074 16.2 0.0 0.0084 16.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 EKX35063.1 - 0.013 15.6 0.1 0.018 15.2 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_4 PF13462.6 EKX35063.1 - 0.085 13.0 0.2 1.1 9.4 0.1 2.0 1 1 1 2 2 2 0 Thioredoxin Redoxin PF08534.10 EKX35063.1 - 0.086 12.6 0.0 0.095 12.4 0.0 1.1 1 0 0 1 1 1 0 Redoxin Uds1 PF15456.6 EKX35064.1 - 0.0098 16.1 14.0 0.0098 16.1 14.0 2.4 2 1 0 2 2 2 1 Up-regulated During Septation Golgin_A5 PF09787.9 EKX35064.1 - 0.27 10.6 33.3 0.027 13.9 9.6 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF3573 PF12097.8 EKX35064.1 - 0.57 8.9 5.5 0.07 12.0 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) NPV_P10 PF05531.12 EKX35064.1 - 0.86 10.1 6.9 65 4.1 6.7 3.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein TMPIT PF07851.13 EKX35064.1 - 2.2 7.5 20.2 0.38 9.9 1.9 2.1 2 0 0 2 2 2 0 TMPIT-like protein TetR_C_13 PF16925.5 EKX35064.1 - 2.2 8.2 8.1 8 6.4 0.3 2.8 2 2 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Histidinol_dh PF00815.20 EKX35064.1 - 8 5.3 9.9 0.7 8.8 1.9 2.1 2 0 0 2 2 2 0 Histidinol dehydrogenase PRESAN PF09687.10 EKX35064.1 - 8.2 7.0 11.8 1.5 9.4 2.5 3.1 2 2 1 3 3 3 0 Plasmodium RESA N-terminal TCL1_MTCP1 PF01840.17 EKX35066.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.5 1 1 0 1 1 1 0 TCL1/MTCP1 family ANF_receptor PF01094.28 EKX35067.1 - 3.9e-75 253.2 0.2 7.6e-43 147.0 0.1 2.2 2 0 0 2 2 2 2 Receptor family ligand binding region Peripla_BP_6 PF13458.6 EKX35067.1 - 2.5e-14 53.7 0.0 2e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 Periplasmic binding protein DUF4448 PF14610.6 EKX35067.1 - 0.18 11.5 0.0 0.48 10.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DivIC PF04977.15 EKX35069.1 - 0.0038 17.0 4.1 0.0038 17.0 4.1 2.2 1 1 0 2 2 2 1 Septum formation initiator STAT_alpha PF01017.20 EKX35069.1 - 0.005 16.8 8.7 0.011 15.6 8.7 1.6 1 1 0 1 1 1 1 STAT protein, all-alpha domain TBD PF12845.7 EKX35069.1 - 0.019 14.9 5.9 0.086 12.7 0.1 3.6 2 1 0 2 2 2 0 TBD domain Leu_zip PF15294.6 EKX35069.1 - 0.052 13.1 10.8 0.064 12.8 10.8 1.1 1 0 0 1 1 1 0 Leucine zipper LMP PF04778.12 EKX35069.1 - 0.061 13.2 2.7 0.098 12.6 2.7 1.3 1 0 0 1 1 1 0 LMP repeated region GAS PF13851.6 EKX35069.1 - 0.064 12.6 16.8 0.57 9.5 4.0 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TACC_C PF05010.14 EKX35069.1 - 0.094 12.5 10.9 0.15 11.9 10.9 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Cnl2_NKP2 PF09447.10 EKX35069.1 - 0.1 12.8 0.1 0.27 11.4 0.1 1.7 1 0 0 1 1 1 0 Cnl2/NKP2 family protein FUSC PF04632.12 EKX35069.1 - 0.1 11.1 2.9 0.15 10.6 2.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Mod_r PF07200.13 EKX35069.1 - 0.16 12.1 14.7 0.65 10.1 5.7 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF713 PF05218.14 EKX35069.1 - 0.19 11.4 5.7 0.28 10.9 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF713) MnmE_helical PF12631.7 EKX35069.1 - 0.25 11.5 2.8 0.28 11.3 2.7 1.4 1 1 0 1 1 1 0 MnmE helical domain Fib_alpha PF08702.10 EKX35069.1 - 0.51 10.5 7.2 0.81 9.9 7.2 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.9 EKX35069.1 - 0.57 10.2 18.2 2.4 8.2 17.7 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HIP1_clath_bdg PF16515.5 EKX35069.1 - 1.1 10.0 16.1 0.57 10.8 4.9 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Atg14 PF10186.9 EKX35069.1 - 1.6 7.8 7.8 2.4 7.2 7.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 EKX35069.1 - 1.7 7.5 15.1 2.9 6.7 5.3 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein TMPIT PF07851.13 EKX35069.1 - 2.7 7.2 5.0 3.6 6.7 5.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein Fmp27_WPPW PF10359.9 EKX35069.1 - 2.7 6.7 7.9 3.7 6.3 7.9 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain FlaC_arch PF05377.11 EKX35069.1 - 4.3 7.8 6.0 6.3 7.3 1.4 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4404 PF14357.6 EKX35069.1 - 7 7.4 11.3 4.6 8.0 1.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) APG6_N PF17675.1 EKX35069.1 - 9.5 6.8 19.4 2 8.9 4.0 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF512 PF04459.12 EKX35070.1 - 0.088 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF512) PGK PF00162.19 EKX35071.1 - 4.1e-163 542.7 0.1 5e-163 542.4 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Pyr_redox PF00070.27 EKX35071.1 - 0.89 10.2 3.1 1.7 9.3 0.1 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Robl_LC7 PF03259.17 EKX35072.1 - 5.9e-21 74.1 0.0 1e-20 73.3 0.0 1.4 2 0 0 2 2 2 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 EKX35072.1 - 0.0028 17.6 0.0 0.004 17.1 0.0 1.2 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 SR-25 PF10500.9 EKX35073.1 - 0.00013 21.7 10.1 0.00013 21.7 10.1 2.9 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein MID_MedPIWI PF18296.1 EKX35073.1 - 0.0016 18.3 4.2 0.0016 18.3 4.2 2.5 3 0 0 3 3 3 1 MID domain of medPIWI DUF3446 PF11928.8 EKX35073.1 - 0.0046 17.2 4.0 0.011 16.0 4.0 1.7 1 0 0 1 1 1 1 Early growth response N-terminal domain DcuA_DcuB PF03605.14 EKX35073.1 - 0.075 11.9 0.2 0.12 11.2 0.2 1.2 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Zip PF02535.22 EKX35073.1 - 2.1 7.5 9.3 2.4 7.3 3.5 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter CLN3 PF02487.17 EKX35073.1 - 2.4 7.1 11.1 0.073 12.1 1.7 2.4 3 0 0 3 3 3 0 CLN3 protein Orf78 PF06024.12 EKX35073.1 - 4.4 7.6 7.1 0.52 10.6 1.1 2.4 2 0 0 2 2 2 0 Orf78 (ac78) RNase_H2_suC PF08615.11 EKX35073.1 - 6.7 6.9 10.9 0.91 9.7 2.0 2.4 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF4050 PF13259.6 EKX35073.1 - 8.4 6.7 16.2 0.041 14.2 2.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4050) GFA PF04828.14 EKX35074.1 - 1.5e-15 57.2 1.6 2.1e-15 56.8 1.6 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme SDH_C PF18317.1 EKX35074.1 - 0.19 11.5 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate 5'-dehydrogenase C-terminal domain RCC1 PF00415.18 EKX35075.1 - 0.0089 16.6 5.5 0.41 11.3 0.2 3.1 2 1 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat Nop14 PF04147.12 EKX35075.1 - 0.2 9.8 1.2 0.2 9.8 1.2 1.0 1 0 0 1 1 1 0 Nop14-like family GEN1_C PF18380.1 EKX35075.1 - 0.32 11.9 2.1 0.47 11.4 2.1 1.2 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain IKKbetaNEMObind PF12179.8 EKX35076.1 - 0.25 11.4 1.9 7 6.8 0.1 3.4 2 1 1 3 3 3 0 I-kappa-kinase-beta NEMO binding domain LAP1C PF05609.12 EKX35076.1 - 0.29 10.2 29.5 0.018 14.1 24.4 1.5 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Suf PF05843.14 EKX35076.1 - 1.7 8.6 14.9 5.1 7.0 14.9 1.8 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) dNK PF01712.19 EKX35077.1 - 2.8e-46 157.9 0.0 3.1e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 EKX35077.1 - 7.2e-08 33.0 0.0 1.1e-06 29.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EKX35077.1 - 1.5e-07 31.7 0.0 9.1e-07 29.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EKX35077.1 - 9.6e-06 25.9 0.0 1.5e-05 25.3 0.0 1.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EKX35077.1 - 0.00066 20.1 0.0 0.53 10.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain Thymidylate_kin PF02223.17 EKX35077.1 - 0.0013 18.4 0.0 1.7 8.3 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase DUF1706 PF08020.11 EKX35077.1 - 0.039 13.9 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) GATase_7 PF13537.6 EKX35078.1 - 4.4e-16 58.9 0.0 8.3e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EKX35078.1 - 4.4e-16 59.3 0.0 7.1e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EKX35078.1 - 0.00018 20.5 0.0 0.00036 19.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Pribosyltran PF00156.27 EKX35078.1 - 0.019 14.5 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain CPSase_L_D2 PF02786.17 EKX35079.1 - 2.1e-107 357.4 0.0 9.6e-79 263.8 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 EKX35079.1 - 1.5e-51 173.6 0.0 9.4e-51 171.0 0.0 2.3 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 EKX35079.1 - 1e-41 142.4 0.1 2.1e-41 141.4 0.1 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.28 EKX35079.1 - 2.3e-41 141.6 0.0 6.8e-41 140.1 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 EKX35079.1 - 3.2e-38 130.8 0.0 8.6e-38 129.4 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 EKX35079.1 - 4e-35 121.2 0.0 1.4e-34 119.4 0.0 2.1 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp PF02222.22 EKX35079.1 - 1.3e-17 63.9 0.0 3.7e-09 36.4 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EKX35079.1 - 2.7e-16 59.7 0.0 7.7e-07 28.8 0.1 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.22 EKX35079.1 - 1.3e-11 44.5 0.0 3.1e-10 40.1 0.0 3.1 3 0 0 3 3 3 1 MGS-like domain ATPgrasp_Ter PF15632.6 EKX35079.1 - 2.2e-09 37.1 0.0 0.0022 17.7 0.0 2.8 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Amidohydro_1 PF01979.20 EKX35079.1 - 3.4e-09 36.5 0.4 8.8e-09 35.1 0.4 1.7 1 0 0 1 1 1 1 Amidohydrolase family Peptidase_C26 PF07722.13 EKX35079.1 - 2.9e-06 27.2 2.0 0.0034 17.2 0.3 3.6 2 1 0 2 2 2 1 Peptidase C26 ATP-grasp_3 PF02655.14 EKX35079.1 - 2.4e-05 24.5 0.2 0.01 15.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 EKX35079.1 - 3.7e-05 23.4 0.0 0.001 18.7 0.0 2.4 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GARS_A PF01071.19 EKX35079.1 - 0.00038 20.3 0.1 0.0034 17.2 0.0 2.3 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DJ-1_PfpI PF01965.24 EKX35079.1 - 0.0082 16.0 0.8 1.7 8.4 0.0 3.5 4 0 0 4 4 4 1 DJ-1/PfpI family C2 PF00168.30 EKX35080.1 - 6.4e-20 71.4 0.0 2.3e-19 69.6 0.0 2.1 1 0 0 1 1 1 1 C2 domain WD40 PF00400.32 EKX35080.1 - 8.3e-19 67.6 11.3 0.012 16.5 0.0 8.4 8 0 0 8 8 8 5 WD domain, G-beta repeat EF-hand_5 PF13202.6 EKX35080.1 - 8.1e-07 28.3 0.0 2.4e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 EKX35080.1 - 3.3e-06 26.8 0.3 1.5e-05 24.7 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX35080.1 - 2.7e-05 23.4 0.0 0.00014 21.2 0.0 2.3 2 0 0 2 2 2 1 EF hand ANAPC4_WD40 PF12894.7 EKX35080.1 - 8.8e-05 22.7 4.9 1.2 9.4 0.0 5.9 6 2 1 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_7 PF13499.6 EKX35080.1 - 0.00028 21.3 0.1 0.00082 19.8 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX35080.1 - 0.00086 19.1 0.0 0.0028 17.4 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain DUF4670 PF15709.5 EKX35080.1 - 0.92 8.8 21.0 1.5 8.0 21.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4670) DUF3874 PF12990.7 EKX35082.1 - 0.16 12.3 0.0 0.23 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknonw function from B. Theta Gene description (DUF3874) DUF563 PF04577.14 EKX35084.1 - 4.1e-17 63.0 0.4 8.5e-17 62.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF563) RWP-RK PF02042.15 EKX35085.1 - 1.3e-14 53.9 0.3 4.4e-14 52.2 0.1 1.8 2 0 0 2 2 2 1 RWP-RK domain HTH_8 PF02954.19 EKX35085.1 - 0.049 13.4 0.3 0.7 9.7 0.0 2.7 2 1 1 3 3 3 0 Bacterial regulatory protein, Fis family RWP-RK PF02042.15 EKX35086.1 - 2.3e-14 53.1 0.1 3.5e-14 52.5 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX35086.1 - 0.029 14.1 0.3 0.58 10.0 0.0 2.7 2 1 1 3 3 3 0 Bacterial regulatory protein, Fis family RWP-RK PF02042.15 EKX35087.1 - 1.5e-09 37.7 0.1 2.2e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_17 PF12728.7 EKX35087.1 - 0.15 12.2 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain SNF2_N PF00176.23 EKX35088.1 - 3.1e-67 226.8 0.2 5.1e-67 226.1 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX35088.1 - 3e-19 69.4 0.0 9.1e-19 67.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EKX35088.1 - 3e-10 39.7 0.3 6.1e-10 38.7 0.3 1.5 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 EKX35088.1 - 2.3e-08 34.2 0.0 1.4e-07 31.6 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit LRR_6 PF13516.6 EKX35089.1 - 6.8e-21 72.5 7.2 0.00016 21.4 0.0 6.7 7 0 0 7 7 7 6 Leucine Rich repeat LRR_4 PF12799.7 EKX35089.1 - 1.8e-08 34.5 0.1 0.0018 18.6 0.0 3.5 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX35089.1 - 1.5e-05 24.9 0.1 0.92 10.3 0.0 5.0 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_8 PF13855.6 EKX35089.1 - 0.00074 19.2 6.1 1.3 8.8 0.1 3.9 2 2 1 3 3 3 2 Leucine rich repeat Glyco_transf_41 PF13844.6 EKX35090.1 - 6.9e-49 166.5 0.0 1.2e-28 99.8 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_8 PF13181.6 EKX35090.1 - 1.3e-09 37.5 0.8 0.0012 18.9 0.1 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX35090.1 - 3.2e-09 36.5 0.1 0.00046 20.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX35090.1 - 6.1e-09 35.3 2.3 0.00062 19.7 0.0 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX35090.1 - 8.1e-09 34.9 0.8 0.00042 20.0 0.2 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX35090.1 - 3.2e-07 29.9 0.0 0.00033 20.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX35090.1 - 5e-06 26.1 0.4 0.0014 18.2 0.0 3.4 3 1 0 3 3 3 1 TPR repeat TPR_12 PF13424.6 EKX35090.1 - 1.3e-05 25.4 0.5 0.00051 20.3 0.4 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX35090.1 - 3.3e-05 24.4 0.3 2.5 9.1 0.0 4.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX35090.1 - 0.00074 19.3 0.2 0.0045 16.8 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX35090.1 - 0.002 18.7 0.1 0.072 13.8 0.0 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 EKX35090.1 - 0.013 14.8 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX35090.1 - 0.091 13.3 0.1 1 9.9 0.2 2.5 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 EKX35090.1 - 0.18 11.9 0.1 0.39 10.8 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat EcoRI_methylase PF13651.6 EKX35093.1 - 0.011 14.9 0.0 0.011 14.9 0.0 1.8 2 0 0 2 2 2 0 Adenine-specific methyltransferase EcoRI DUF1168 PF06658.12 EKX35093.1 - 0.037 13.9 12.6 0.06 13.2 12.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Tim54 PF11711.8 EKX35093.1 - 0.85 8.3 7.4 0.43 9.3 5.1 1.7 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 TFIIF_alpha PF05793.12 EKX35093.1 - 1 7.9 17.3 1.4 7.4 17.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) N6_Mtase PF02384.16 EKX35093.1 - 1.6 8.0 5.2 0.67 9.2 0.1 2.3 2 1 1 3 3 3 0 N-6 DNA Methylase NPR3 PF03666.13 EKX35093.1 - 2.3 6.9 8.5 3.6 6.3 8.5 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 EKX35093.1 - 2.4 6.4 13.1 2.7 6.2 13.1 1.1 1 0 0 1 1 1 0 CDC45-like protein EMP70 PF02990.16 EKX35094.1 - 2.6e-150 501.5 11.1 4.1e-150 500.9 11.1 1.3 1 0 0 1 1 1 1 Endomembrane protein 70 FYDLN_acid PF09538.10 EKX35095.1 - 5.2 7.8 7.8 4.4 8.0 4.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Hist_deacetyl PF00850.19 EKX35096.1 - 4.7e-74 249.6 0.0 6.5e-74 249.2 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain peroxidase PF00141.23 EKX35097.1 - 3.4e-09 36.8 0.0 4.3e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Peroxidase IL28A PF15177.6 EKX35101.1 - 0.015 15.2 0.0 0.059 13.2 0.0 2.0 2 0 0 2 2 2 0 Interleukin-28A Syntaxin_2 PF14523.6 EKX35101.1 - 0.092 13.1 0.3 0.37 11.2 0.1 2.1 2 0 0 2 2 2 0 Syntaxin-like protein Amelogenin PF02948.15 EKX35103.1 - 0.14 12.8 7.5 0.26 11.9 7.5 1.3 1 0 0 1 1 1 0 Amelogenin FAP PF07174.11 EKX35103.1 - 0.35 10.3 3.9 0.54 9.7 3.9 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Dynein_C PF18199.1 EKX35104.1 - 0.0025 17.1 0.1 0.0029 16.9 0.1 1.1 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain UPF0160 PF03690.13 EKX35104.1 - 0.0041 16.8 0.2 0.0047 16.6 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) PHM7_cyt PF14703.6 EKX35104.1 - 0.012 15.9 0.3 0.74 10.0 0.0 2.1 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter NIL PF09383.10 EKX35104.1 - 0.091 12.6 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 NIL domain TMEM220 PF15071.6 EKX35106.1 - 0.71 10.7 6.3 0.52 11.1 0.5 3.0 2 0 0 2 2 2 0 Transmembrane family 220, helix DUF2156 PF09924.9 EKX35109.1 - 0.0047 16.0 0.1 0.007 15.4 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) NDK PF00334.19 EKX35109.1 - 0.072 13.1 0.1 4.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Nucleoside diphosphate kinase LPP20 PF02169.16 EKX35109.1 - 0.11 12.8 0.7 0.23 11.8 0.7 1.5 1 0 0 1 1 1 0 LPP20 lipoprotein DENN PF02141.21 EKX35110.1 - 0.014 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 DENN (AEX-3) domain HSBP1 PF06825.12 EKX35110.1 - 0.27 11.1 2.1 3.7 7.5 0.2 2.5 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Alpha_kinase PF02816.18 EKX35111.1 - 8.7e-27 94.4 0.0 1.1e-26 94.0 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Peptidase_M16_C PF05193.21 EKX35112.1 - 1.3e-36 126.3 0.0 3.2e-18 66.4 0.0 3.0 3 1 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EKX35112.1 - 1.4e-21 77.0 4.3 3.5e-17 62.8 0.1 3.6 3 0 0 3 3 3 2 Insulinase (Peptidase family M16) CYLD_phos_site PF16607.5 EKX35112.1 - 0.028 14.3 0.3 0.054 13.4 0.3 1.4 1 0 0 1 1 1 0 Phosphorylation region of CYLD, unstructured R3H-assoc PF13902.6 EKX35113.1 - 5 7.5 8.5 22 5.4 3.5 2.8 2 1 1 3 3 3 0 R3H-associated N-terminal domain WD40 PF00400.32 EKX35114.1 - 1.6e-59 196.4 41.5 6.6e-10 39.4 2.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX35114.1 - 6.6e-27 93.6 11.7 0.00022 21.5 0.1 6.4 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EKX35114.1 - 6.1e-07 29.1 0.0 0.83 8.9 0.0 4.7 4 2 0 4 4 4 2 WD40-like domain PQQ_3 PF13570.6 EKX35114.1 - 0.00018 21.9 7.0 14 6.3 0.4 5.1 5 1 0 5 5 5 1 PQQ-like domain Cir_N PF10197.9 EKX35114.1 - 0.0033 17.6 3.0 64 3.9 0.0 5.4 6 0 0 6 6 6 0 N-terminal domain of CBF1 interacting co-repressor CIR PD40 PF07676.12 EKX35114.1 - 0.02 14.8 10.9 28 4.8 0.1 5.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Glyco_hydro2_C5 PF18565.1 EKX35114.1 - 0.17 11.8 0.1 13 5.7 0.0 2.5 2 0 0 2 2 2 0 Glycoside hydrolase family 2 C-terminal domain 5 ChapFlgA PF13144.6 EKX35114.1 - 0.24 11.5 0.9 82 3.3 0.0 4.0 6 0 0 6 6 6 0 Chaperone for flagella basal body P-ring formation C2-set_2 PF08205.12 EKX35114.1 - 1.8 8.7 5.7 1.4 9.0 0.1 3.5 3 2 1 4 4 4 0 CD80-like C2-set immunoglobulin domain IKI3 PF04762.12 EKX35114.1 - 2.4 6.0 8.8 1.9 6.4 0.7 2.5 1 1 1 2 2 2 0 IKI3 family NDUF_B7 PF05676.13 EKX35115.1 - 7.3e-25 86.5 4.9 8.5e-25 86.3 4.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 EKX35115.1 - 0.039 14.0 3.9 0.05 13.6 3.9 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 EKX35115.1 - 0.43 10.9 4.5 2.9 8.3 1.7 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 GerD PF17898.1 EKX35116.1 - 2.5e-06 27.4 10.2 5.7e-06 26.3 10.2 1.5 1 0 0 1 1 1 1 Spore germination GerD central core domain STI1 PF17830.1 EKX35116.1 - 6.7e-06 25.9 19.3 0.0074 16.2 6.5 4.2 3 2 1 4 4 4 2 STI1 domain Com_YlbF PF06133.11 EKX35116.1 - 0.00018 22.0 4.6 0.00018 22.0 4.6 2.5 3 1 0 3 3 3 1 Control of competence regulator ComK, YlbF/YmcA XPC-binding PF09280.11 EKX35116.1 - 0.46 10.3 4.6 1.6 8.5 0.5 2.8 2 1 0 2 2 2 0 XPC-binding domain Coq4 PF05019.13 EKX35116.1 - 0.65 9.3 3.4 8 5.7 0.2 2.3 2 0 0 2 2 2 0 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 EMC3_TMCO1 PF01956.16 EKX35116.1 - 8.7 6.0 11.0 19 4.9 11.0 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Collagen PF01391.18 EKX35117.1 - 2.1e-16 59.4 68.4 2.1e-09 37.0 31.5 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) GAS PF13851.6 EKX35117.1 - 0.14 11.5 5.6 0.25 10.7 5.6 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Myb_DNA-binding PF00249.31 EKX35121.1 - 1.2e-11 44.6 0.1 3.7e-11 43.0 0.1 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain TEA PF01285.18 EKX35121.1 - 0.016 15.3 0.3 1.2 9.3 0.0 2.0 1 1 1 2 2 2 0 TEA/ATTS domain Myb_DNA-bind_6 PF13921.6 EKX35121.1 - 0.017 15.4 0.0 0.021 15.1 0.0 1.2 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EKX35121.1 - 0.09 12.7 0.2 0.098 12.6 0.2 1.3 1 1 0 1 1 1 0 Myb DNA-binding like Myb_DNA-binding PF00249.31 EKX35122.1 - 1.3e-11 44.5 0.1 4.2e-11 42.8 0.1 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX35122.1 - 0.015 15.5 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain TEA PF01285.18 EKX35122.1 - 0.017 15.2 0.3 1.3 9.1 0.0 2.1 1 1 1 2 2 2 0 TEA/ATTS domain Myb_DNA-binding PF00249.31 EKX35123.1 - 1.9e-07 31.2 0.1 5.2e-07 29.8 0.1 1.8 1 1 0 1 1 1 1 Myb-like DNA-binding domain Ank PF00023.30 EKX35124.1 - 8.9e-20 70.2 0.3 1.4e-05 25.3 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EKX35124.1 - 8.7e-17 61.3 0.0 9.3e-06 26.1 0.1 3.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX35124.1 - 1.9e-15 57.2 0.1 1.2e-06 29.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX35124.1 - 2.7e-14 53.0 0.4 3.7e-06 27.1 0.1 3.1 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX35124.1 - 4.6e-11 41.9 0.3 0.0086 16.5 0.0 3.7 3 1 0 3 3 3 3 Ankyrin repeat Myb_DNA-binding PF00249.31 EKX35125.1 - 3.9e-10 39.8 0.7 2.7e-09 37.1 0.7 1.9 1 1 0 1 1 1 1 Myb-like DNA-binding domain TEA PF01285.18 EKX35125.1 - 0.0044 17.1 0.1 0.0069 16.4 0.1 1.3 1 1 0 1 1 1 1 TEA/ATTS domain Myb_DNA-binding PF00249.31 EKX35126.1 - 4.7e-09 36.3 0.1 4.1e-08 33.3 0.1 2.3 1 1 0 1 1 1 1 Myb-like DNA-binding domain RasGEF_N_2 PF14663.6 EKX35126.1 - 0.11 12.9 0.5 12 6.3 0.1 2.2 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Rv2175c_C PF18367.1 EKX35126.1 - 0.15 12.2 0.0 0.27 11.3 0.0 1.6 1 1 0 1 1 1 0 Rv2175c C-terminal domain of unknown function Laminin_EGF PF00053.24 EKX35127.1 - 9.2e-05 22.5 7.1 9.2e-05 22.5 7.1 2.6 3 0 0 3 3 3 1 Laminin EGF domain EGF_2 PF07974.13 EKX35127.1 - 0.00069 19.9 6.2 0.00069 19.9 6.2 3.7 3 1 0 3 3 3 1 EGF-like domain EGF_2 PF07974.13 EKX35128.1 - 0.0038 17.6 2.3 0.0038 17.6 2.3 8.4 6 1 1 7 7 7 5 EGF-like domain PDZ_2 PF13180.6 EKX35131.1 - 3.7e-09 36.8 1.6 2.6e-07 30.9 1.6 2.1 1 1 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX35131.1 - 0.00026 20.8 0.8 0.0063 16.3 0.5 2.2 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX35131.1 - 0.00031 21.0 0.6 0.00043 20.6 0.6 1.4 1 1 0 1 1 1 1 PDZ domain PDZ_4 PF17816.1 EKX35131.1 - 0.03 14.7 0.1 0.053 13.9 0.1 1.4 1 1 0 1 1 1 0 PDZ domain Cadherin_4 PF17803.1 EKX35132.1 - 0.0086 16.7 0.2 0.026 15.2 0.2 1.8 1 0 0 1 1 1 1 Bacterial cadherin-like domain LMF1 PF06762.14 EKX35132.1 - 0.023 13.8 4.4 0.089 11.9 1.0 2.2 2 0 0 2 2 2 0 Lipase maturation factor Big_9 PF17963.1 EKX35132.1 - 0.081 13.7 0.4 0.43 11.4 0.2 2.4 2 0 0 2 2 2 0 Bacterial Ig domain CRA PF06589.11 EKX35133.1 - 0.03 14.4 0.0 0.04 14.0 0.0 1.1 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) PQ-loop PF04193.14 EKX35134.1 - 2.2e-12 46.5 0.4 2.2e-12 46.5 0.4 1.5 2 0 0 2 2 2 1 PQ loop repeat Peptidase_S8 PF00082.22 EKX35135.1 - 3.4e-21 75.8 0.0 7e-21 74.8 0.0 1.5 1 1 0 1 1 1 1 Subtilase family DUF1775 PF07987.11 EKX35136.1 - 0.00011 22.5 0.0 0.00031 21.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unkown function (DUF1775) AAA_18 PF13238.6 EKX35137.1 - 0.0012 19.4 0.4 0.048 14.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EKX35137.1 - 0.0035 17.6 1.0 1.2 9.3 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.6 EKX35137.1 - 0.004 17.2 0.0 0.018 15.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EKX35137.1 - 0.046 13.4 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EKX35137.1 - 0.055 13.8 0.1 0.19 12.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EKX35137.1 - 0.069 12.7 0.1 0.2 11.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EKX35137.1 - 0.094 13.1 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EKX35137.1 - 0.14 11.9 0.0 0.14 11.9 0.0 3.7 3 1 0 3 3 3 0 AAA domain AAA_16 PF13191.6 EKX35137.1 - 0.16 12.3 2.8 0.18 12.1 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain Str_synth PF03088.16 EKX35139.1 - 0.059 13.5 0.1 0.59 10.3 0.0 2.6 2 1 1 3 3 3 0 Strictosidine synthase HEAT PF02985.22 EKX35140.1 - 0.00095 19.2 0.5 2.5e+02 2.4 0.0 5.3 5 0 0 5 5 5 0 HEAT repeat AAA_28 PF13521.6 EKX35140.1 - 0.0021 18.3 0.3 1.5 9.1 0.0 3.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EKX35140.1 - 0.0051 16.8 0.0 0.023 14.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EKX35140.1 - 0.0092 16.5 3.5 0.062 13.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 EKX35140.1 - 0.055 13.0 0.0 0.23 11.0 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EKX35140.1 - 0.066 13.6 0.1 0.23 11.8 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EKX35140.1 - 0.1 13.0 0.0 0.33 11.4 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX35140.1 - 0.22 11.9 0.0 0.22 11.9 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain Dpoe2NT PF12213.8 EKX35140.1 - 1.2 9.5 21.6 1.8 8.9 0.9 5.2 3 1 2 5 5 5 0 DNA polymerases epsilon N terminal Atx10homo_assoc PF09759.9 EKX35140.1 - 4.2 7.5 22.9 13 5.9 0.7 5.6 4 1 2 6 6 6 0 Spinocerebellar ataxia type 10 protein domain RWP-RK PF02042.15 EKX35142.1 - 7.2e-15 54.7 0.0 1.3e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain RP-C_C PF11800.8 EKX35142.1 - 5.5 7.0 0.0 5.5 7.0 0.0 2.6 2 1 0 2 2 2 0 Replication protein C C-terminal region PAS PF00989.25 EKX35143.1 - 0.00022 21.2 0.0 0.043 13.8 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 EKX35143.1 - 0.00025 21.2 0.0 1.5 9.1 0.0 2.8 3 0 0 3 3 3 2 PAS domain Kinocilin PF15033.6 EKX35144.1 - 0.11 12.1 0.1 0.22 11.2 0.0 1.6 1 1 1 2 2 2 0 Kinocilin protein Pro_isomerase PF00160.21 EKX35145.1 - 1.1e-44 152.5 0.2 1.4e-44 152.2 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CS PF04969.16 EKX35145.1 - 1.8e-09 38.5 0.1 4.6e-09 37.2 0.0 1.7 1 1 1 2 2 2 1 CS domain RRM_1 PF00076.22 EKX35146.1 - 1.9e-16 59.6 0.5 2.8e-16 59.1 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EKX35146.1 - 7.6e-06 25.5 0.0 8.8e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EKX35146.1 - 0.083 13.0 0.1 0.25 11.5 0.1 2.0 1 1 0 1 1 1 0 RNA recognition motif HAS-barrel PF09378.10 EKX35146.1 - 0.11 12.6 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 HAS barrel domain Mito_fiss_reg PF05308.11 EKX35147.1 - 0.011 15.8 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Mustang PF15682.5 EKX35147.1 - 0.047 13.8 0.1 15 5.7 0.0 2.7 2 0 0 2 2 2 0 Musculoskeletal, temporally activated-embryonic nuclear protein 1 Methyltransf_23 PF13489.6 EKX35150.1 - 1.6e-06 28.0 0.0 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX35150.1 - 0.00074 20.1 0.0 0.0011 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Sorb PF02208.16 EKX35150.1 - 0.03 14.2 0.0 2.3 8.1 0.0 2.6 2 0 0 2 2 2 0 Sorbin homologous domain Methyltransf_12 PF08242.12 EKX35150.1 - 0.055 14.2 0.0 0.087 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EKX35150.1 - 0.07 13.8 0.0 0.13 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ank_2 PF12796.7 EKX35153.1 - 1e-05 26.0 0.2 0.019 15.6 0.0 1.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX35153.1 - 7.2e-05 23.3 0.1 0.00082 19.9 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX35153.1 - 0.0054 17.1 0.6 0.029 14.8 0.4 2.2 2 1 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EKX35153.1 - 0.027 15.0 0.1 0.22 12.2 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.6 EKX35153.1 - 0.092 13.1 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (many copies) TerD PF02342.18 EKX35154.1 - 1.4e-08 34.5 0.0 2.6e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 TerD domain Rdx PF10262.9 EKX35154.1 - 0.0001 22.4 0.0 0.00021 21.4 0.0 1.6 1 0 0 1 1 1 1 Rdx family DUF4542 PF15075.6 EKX35154.1 - 0.031 14.7 0.1 0.34 11.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4542) Macoilin PF09726.9 EKX35155.1 - 0.00012 20.9 19.2 0.00012 20.9 19.2 2.1 1 1 1 2 2 2 1 Macoilin family TolA_bind_tri PF16331.5 EKX35155.1 - 0.023 14.8 1.4 0.023 14.8 1.4 5.0 2 2 3 5 5 5 0 TolA binding protein trimerisation GAS PF13851.6 EKX35155.1 - 0.097 12.0 44.7 0.24 10.7 18.8 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 EKX35155.1 - 0.56 10.4 41.7 0.75 10.0 17.9 2.6 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) FPP PF05911.11 EKX35155.1 - 1.9 6.6 45.0 0.11 10.6 16.7 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Spc7 PF08317.11 EKX35155.1 - 2.3 7.0 49.6 11 4.7 17.5 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein SIR2 PF02146.17 EKX35156.1 - 2.8e-19 69.7 0.0 4.2e-12 46.4 0.0 2.2 1 1 1 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.22 EKX35156.1 - 0.00064 19.5 0.0 1.2 8.9 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Opiods_neuropep PF01160.18 EKX35157.1 - 0.048 13.7 0.2 0.074 13.2 0.2 1.3 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide PBP_like_2 PF12849.7 EKX35158.1 - 2.9e-33 115.8 3.2 3.9e-33 115.3 3.2 1.1 1 0 0 1 1 1 1 PBP superfamily domain PBP_like PF12727.7 EKX35158.1 - 0.0012 18.0 0.1 0.022 13.9 0.0 2.3 2 0 0 2 2 2 1 PBP superfamily domain MCM_OB PF17207.3 EKX35159.1 - 0.65 9.9 0.0 0.65 9.9 0.0 2.8 2 1 1 3 3 3 0 MCM OB domain Phage_connect_1 PF05135.13 EKX35161.1 - 0.091 13.3 1.4 6.9 7.2 0.1 2.7 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein Peptidase_M3_N PF08439.10 EKX35161.1 - 0.99 9.7 5.2 5 7.5 0.5 3.1 2 0 0 2 2 2 0 Oligopeptidase F DUF812 PF05667.11 EKX35161.1 - 1.3 7.8 12.0 0.23 10.3 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Rho_Binding PF08912.11 EKX35161.1 - 2.2 9.2 9.6 15 6.5 1.4 2.8 2 0 0 2 2 2 0 Rho Binding Hexokinase_2 PF03727.16 EKX35161.1 - 8.8 5.7 6.6 22 4.3 1.4 2.4 2 0 0 2 2 2 0 Hexokinase YabA PF06156.13 EKX35161.1 - 9 7.0 6.2 29 5.3 0.7 2.7 2 0 0 2 2 2 0 Initiation control protein YabA AA_permease_2 PF13520.6 EKX35162.1 - 0.03 13.2 4.5 0.052 12.4 3.7 1.6 1 1 1 2 2 2 0 Amino acid permease Pkinase PF00069.25 EKX35163.1 - 8.5e-67 225.3 0.0 1.2e-66 224.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX35163.1 - 2.2e-30 105.8 0.0 3.1e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 EKX35163.1 - 7.6e-14 50.1 1.3 0.0003 20.1 0.0 4.5 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 EKX35163.1 - 3.4e-13 48.4 0.7 0.0012 18.7 0.2 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 EKX35163.1 - 3.7e-13 49.7 1.6 3.3e-05 24.2 0.2 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 EKX35163.1 - 6.8e-13 48.3 2.0 6.1e-09 35.6 0.1 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EKX35163.1 - 9.9e-07 28.0 2.1 0.018 14.5 0.0 4.0 4 0 0 4 4 4 2 EF hand Kinase-like PF14531.6 EKX35163.1 - 2.3e-05 23.9 0.1 0.00015 21.1 0.1 2.1 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EKX35163.1 - 4.7e-05 22.8 0.0 8.9e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.7 EKX35163.1 - 0.011 15.6 0.1 0.63 10.0 0.0 2.4 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand APH PF01636.23 EKX35163.1 - 0.018 14.9 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family EFhand_Ca_insen PF08726.10 EKX35163.1 - 0.023 14.8 0.1 2.7 8.2 0.0 2.7 2 1 0 2 2 2 0 Ca2+ insensitive EF hand FTA2 PF13095.6 EKX35163.1 - 0.043 13.4 0.1 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EKX35163.1 - 0.048 12.4 0.0 0.075 11.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase TPR_2 PF07719.17 EKX35164.1 - 3.8e-10 39.1 9.3 3.2e-05 23.7 1.2 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX35164.1 - 1.7e-09 37.1 8.9 0.00016 21.3 1.9 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX35164.1 - 2e-06 28.1 1.3 0.03 15.1 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX35164.1 - 2.2e-06 27.4 4.7 0.32 11.3 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX35164.1 - 1.3e-05 25.3 0.4 0.0065 16.6 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX35164.1 - 0.00015 22.0 1.5 0.0019 18.4 0.5 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX35164.1 - 0.0015 18.4 1.9 0.0038 17.2 0.3 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX35164.1 - 0.0042 17.7 0.7 0.48 11.1 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX35164.1 - 0.027 14.3 1.5 0.075 12.9 0.4 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EKX35164.1 - 0.084 12.6 2.6 0.51 10.1 3.2 2.1 2 1 0 2 2 2 0 TPR repeat MIT PF04212.18 EKX35164.1 - 0.094 12.8 3.3 2.2 8.4 1.2 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 EKX35164.1 - 0.78 10.5 4.2 0.72 10.6 0.3 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PDZ PF00595.24 EKX35165.1 - 4.6e-08 33.3 0.0 7.4e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX35165.1 - 6.3e-08 32.3 0.0 9.2e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX35165.1 - 5.3e-05 23.5 0.1 9.3e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Thyroglob_assoc PF16597.5 EKX35165.1 - 0.0025 18.1 1.0 0.0045 17.3 1.0 1.4 1 0 0 1 1 1 1 Thyroglobulin_1 repeat associated disordered domain NYD-SP28 PF14772.6 EKX35168.1 - 4.9e-16 58.6 7.5 4.9e-16 58.6 7.5 4.8 4 2 0 4 4 4 1 Sperm tail NYD-SP28_assoc PF14775.6 EKX35168.1 - 1.3e-10 41.2 1.5 1.3e-10 41.2 1.5 2.9 3 0 0 3 3 3 1 Sperm tail C-terminal domain HMG_box_2 PF09011.10 EKX35168.1 - 0.086 13.4 1.4 0.37 11.4 1.4 2.1 1 0 0 1 1 1 0 HMG-box domain HCV_env PF01539.17 EKX35168.1 - 0.15 11.7 0.2 0.3 10.8 0.2 1.4 1 0 0 1 1 1 0 Hepatitis C virus envelope glycoprotein E1 HALZ PF02183.18 EKX35168.1 - 0.22 11.8 6.7 1.8 8.8 0.8 3.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper Egg_lysin PF01303.17 EKX35168.1 - 0.27 11.4 4.8 0.33 11.2 1.0 2.9 2 1 0 2 2 2 0 Egg lysin (Sperm-lysin) DUF1043 PF06295.12 EKX35168.1 - 1.4 8.9 18.0 0.18 11.8 0.6 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1043) DUF4614 PF15391.6 EKX35169.1 - 0.0022 18.0 1.3 0.0046 17.0 1.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4614) HTH_42 PF06224.12 EKX35169.1 - 0.013 15.1 0.5 0.017 14.7 0.1 1.4 2 0 0 2 2 2 0 Winged helix DNA-binding domain HTH_Tnp_Tc5 PF03221.16 EKX35170.1 - 3.1e-05 23.9 0.1 6.3e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CUE PF02845.16 EKX35171.1 - 2.8e-12 46.1 0.1 4.9e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.6 EKX35171.1 - 0.0041 16.9 0.3 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 UBA-like domain DMA PF03474.14 EKX35171.1 - 0.19 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 DMRTA motif Ank_4 PF13637.6 EKX35172.1 - 1.5e-14 54.2 0.0 1.6e-10 41.3 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX35172.1 - 7.9e-13 48.8 0.0 4.4e-11 43.2 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX35172.1 - 8.5e-12 45.1 0.0 3e-05 24.2 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX35172.1 - 4.5e-09 36.3 0.0 0.00032 21.0 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EKX35172.1 - 2.9e-08 33.3 0.0 0.0018 18.6 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat GST_N_3 PF13417.6 EKX35174.1 - 1e-18 67.5 0.0 1.4e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EKX35174.1 - 4.5e-05 23.7 0.0 6.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 EKX35174.1 - 0.00061 20.0 0.0 0.00094 19.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N PF02798.20 EKX35174.1 - 0.014 15.8 0.0 0.02 15.2 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Na_H_Exchanger PF00999.21 EKX35175.1 - 1.3e-35 122.9 24.9 1.8e-35 122.5 24.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family EGF_2 PF07974.13 EKX35175.1 - 9e-12 45.2 48.6 0.00025 21.3 11.9 3.7 3 0 0 3 3 3 3 EGF-like domain EGF_Tenascin PF18720.1 EKX35175.1 - 0.04 14.0 38.0 0.29 11.2 11.3 3.5 3 0 0 3 3 3 0 Tenascin EGF domain hEGF PF12661.7 EKX35175.1 - 0.056 14.1 24.7 0.1 13.3 4.9 3.9 3 0 0 3 3 3 0 Human growth factor-like EGF Laminin_EGF PF00053.24 EKX35175.1 - 0.15 12.2 48.5 0.041 14.0 7.4 4.1 1 1 3 4 4 4 0 Laminin EGF domain EGF PF00008.27 EKX35175.1 - 0.48 10.8 45.9 1.3 9.3 9.2 3.7 3 0 0 3 3 3 0 EGF-like domain EGF_alliinase PF04863.13 EKX35175.1 - 0.54 10.7 38.1 0.39 11.1 12.6 3.8 2 1 1 3 3 3 0 Alliinase EGF-like domain Sec20 PF03908.13 EKX35176.1 - 1.7e-05 24.7 1.6 2.1e-05 24.3 1.6 1.1 1 0 0 1 1 1 1 Sec20 DUF5383 PF17355.2 EKX35176.1 - 0.00022 21.6 1.1 0.00027 21.3 1.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5383) V-SNARE_C PF12352.8 EKX35176.1 - 0.00024 21.3 4.9 0.00034 20.8 4.9 1.2 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus SNARE PF05739.19 EKX35176.1 - 0.00035 20.5 2.1 0.00055 19.9 2.1 1.4 1 0 0 1 1 1 1 SNARE domain Fusion_gly PF00523.18 EKX35176.1 - 0.00083 17.7 3.7 0.0013 17.1 3.7 1.3 1 1 0 1 1 1 1 Fusion glycoprotein F0 Prominin PF05478.11 EKX35176.1 - 0.0033 15.5 0.5 0.0036 15.3 0.5 1.0 1 0 0 1 1 1 1 Prominin DUF3584 PF12128.8 EKX35176.1 - 0.023 12.3 6.3 0.027 12.0 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMPIT PF07851.13 EKX35176.1 - 0.035 13.4 1.2 0.039 13.2 1.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein MCU PF04678.13 EKX35176.1 - 0.035 14.2 1.4 0.04 14.0 1.4 1.1 1 0 0 1 1 1 0 Mitochondrial calcium uniporter MCPsignal PF00015.21 EKX35176.1 - 0.036 13.9 5.5 0.048 13.5 5.5 1.1 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain LRRC37AB_C PF14914.6 EKX35176.1 - 0.047 13.6 2.3 0.071 13.0 2.3 1.3 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain Synaptobrevin PF00957.21 EKX35176.1 - 0.26 11.1 5.7 1 9.2 5.7 2.0 1 1 0 1 1 1 0 Synaptobrevin DUF2116 PF09889.9 EKX35176.1 - 1.6 8.7 3.5 0.78 9.8 1.2 1.6 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) EF-hand_1 PF00036.32 EKX35177.1 - 1.2e-11 43.2 0.2 5.1e-06 25.7 0.0 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX35177.1 - 6.2e-10 38.2 0.1 5.2e-06 26.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EKX35177.1 - 3.3e-09 37.1 0.0 4.7e-09 36.6 0.0 1.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX35177.1 - 2.5e-07 29.9 0.8 8.2e-05 21.9 0.1 2.1 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX35177.1 - 2.1e-06 27.5 0.2 7e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_9 PF14658.6 EKX35177.1 - 0.032 14.6 0.0 0.065 13.6 0.0 1.5 1 1 0 1 1 1 0 EF-hand domain HMG_box PF00505.19 EKX35178.1 - 1.9e-16 60.2 3.8 2.5e-08 34.2 0.0 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EKX35178.1 - 1.3e-11 44.9 6.2 6.8e-06 26.6 0.2 2.5 2 0 0 2 2 2 2 HMG-box domain YABBY PF04690.13 EKX35178.1 - 6.3e-07 30.1 1.2 2.6e-05 24.9 0.3 2.6 2 1 0 2 2 2 1 YABBY protein CENP-B_dimeris PF09026.10 EKX35178.1 - 9.1e-05 22.8 33.0 0.0017 18.7 9.4 2.6 2 0 0 2 2 2 2 Centromere protein B dimerisation domain PBP1_TM PF14812.6 EKX35178.1 - 0.00076 19.8 27.1 0.019 15.3 12.7 2.8 2 0 0 2 2 2 2 Transmembrane domain of transglycosylase PBP1 at N-terminal BSP_II PF05432.11 EKX35178.1 - 0.13 12.0 29.8 0.32 10.7 29.8 1.6 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Radial_spoke PF04712.12 EKX35178.1 - 1.9 7.3 23.6 0.47 9.3 3.0 2.5 2 0 0 2 2 2 0 Radial spokehead-like protein GCIP PF13324.6 EKX35178.1 - 2 8.0 14.0 1.8 8.1 2.5 2.2 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting MPP6 PF10175.9 EKX35178.1 - 2.3 8.7 19.5 0.14 12.7 5.4 2.5 2 0 0 2 2 2 0 M-phase phosphoprotein 6 SAPS PF04499.15 EKX35178.1 - 10 4.8 9.2 16 4.1 9.2 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Cupin_8 PF13621.6 EKX35179.1 - 1.5e-19 70.8 0.0 9.5e-17 61.5 0.2 2.2 1 1 1 2 2 2 2 Cupin-like domain JmjC PF02373.22 EKX35179.1 - 0.0037 17.7 0.0 0.0054 17.1 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 EKX35179.1 - 0.0066 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein DUF2722 PF10846.8 EKX35180.1 - 3.2e-06 26.4 6.4 3.2e-06 26.4 6.4 3.3 3 1 0 3 3 3 1 Protein of unknown function (DUF2722) HNOBA PF07701.14 EKX35180.1 - 0.037 13.5 5.3 0.7 9.3 0.1 2.5 2 0 0 2 2 2 0 Heme NO binding associated Velvet PF11754.8 EKX35180.1 - 0.69 9.8 18.1 0.17 11.8 4.2 2.5 2 0 0 2 2 2 0 Velvet factor Spt20 PF12090.8 EKX35180.1 - 0.72 9.4 54.1 0.062 12.9 27.3 2.4 2 0 0 2 2 2 0 Spt20 family DUF4471 PF14740.6 EKX35180.1 - 8.8 5.4 15.0 3.9 6.6 3.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) PB1 PF00564.24 EKX35181.1 - 0.00018 21.3 0.2 0.00044 20.1 0.2 1.8 1 1 0 1 1 1 1 PB1 domain CtsR_C PF17727.1 EKX35183.1 - 0.054 13.6 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 CtsR C-terminal dimerization domain SoDot-IcmSS PF16848.5 EKX35184.1 - 0.044 13.8 0.1 0.099 12.6 0.1 1.5 1 0 0 1 1 1 0 Substrate of the Dot/Icm secretion system, putative DUF3566 PF12089.8 EKX35184.1 - 0.59 10.5 12.3 0.37 11.1 0.8 4.1 4 0 0 4 4 4 0 Transmembrane domain of unknown function (DUF3566) RNase_H_2 PF13482.6 EKX35185.1 - 8.1e-15 55.2 1.5 1.9e-14 54.0 1.5 1.5 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 EKX35185.1 - 6.9e-07 29.2 0.7 0.015 15.0 0.2 2.1 1 1 1 2 2 2 2 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_A_exo1 PF01612.20 EKX35185.1 - 2.3e-05 24.2 0.4 3.2e-05 23.7 0.4 1.1 1 0 0 1 1 1 1 3'-5' exonuclease DNA_pol_B_exo1 PF03104.19 EKX35185.1 - 0.0047 16.1 1.2 0.25 10.5 1.2 2.2 1 1 0 1 1 1 1 DNA polymerase family B, exonuclease domain RNase_T PF00929.24 EKX35185.1 - 0.037 14.6 1.2 0.21 12.1 0.2 2.4 1 1 1 2 2 2 0 Exonuclease DcpS_C PF11969.8 EKX35190.1 - 1.8e-21 76.7 0.8 2.7e-21 76.2 0.8 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EKX35190.1 - 0.0024 18.6 0.3 0.0041 17.8 0.3 1.3 1 0 0 1 1 1 1 HIT domain SRP-alpha_N PF04086.13 EKX35191.1 - 0.31 10.9 31.4 0.36 10.7 31.4 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Apt1 PF10351.9 EKX35191.1 - 0.81 8.5 17.6 1.1 8.1 17.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hamartin PF04388.12 EKX35191.1 - 2.5 6.6 17.3 2.8 6.5 17.3 1.1 1 0 0 1 1 1 0 Hamartin protein LAP1C PF05609.12 EKX35191.1 - 3.2 6.7 22.2 4 6.4 22.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Hid1 PF12722.7 EKX35191.1 - 5.3 5.0 19.4 6 4.9 19.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SLC12 PF03522.15 EKX35191.1 - 8.3 5.3 20.1 11 4.9 20.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 PI3K_1B_p101 PF10486.9 EKX35191.1 - 9.2 3.9 16.0 11 3.7 16.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Peptidase_C58 PF03543.14 EKX35192.1 - 0.073 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen ATP-synt_E PF05680.12 EKX35194.1 - 1.6e-09 37.9 0.9 1.8e-09 37.8 0.9 1.1 1 0 0 1 1 1 1 ATP synthase E chain DivIC PF04977.15 EKX35194.1 - 0.01 15.5 0.6 0.013 15.3 0.6 1.1 1 0 0 1 1 1 0 Septum formation initiator Cnd3 PF12719.7 EKX35196.1 - 5.7e-39 134.1 4.6 1.3e-38 132.9 1.9 2.7 2 2 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 EKX35196.1 - 2.6e-06 27.2 15.1 0.38 11.1 0.1 8.4 9 0 0 9 9 9 2 HEAT repeat Cnd1 PF12717.7 EKX35196.1 - 3.7e-05 23.8 1.7 3.3 7.7 0.0 4.5 3 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EKX35196.1 - 8.5e-05 22.9 5.5 0.22 11.9 0.0 5.0 5 0 0 5 5 5 2 HEAT repeats OAM_alpha PF16552.5 EKX35196.1 - 0.01 15.7 0.1 0.028 14.3 0.1 1.7 1 0 0 1 1 1 0 D-ornithine 4,5-aminomutase alpha-subunit TIP120 PF08623.10 EKX35196.1 - 0.069 12.9 4.1 0.54 10.0 0.0 3.4 4 0 0 4 4 4 0 TATA-binding protein interacting (TIP20) MGDG_synth PF06925.11 EKX35197.1 - 1.3e-20 74.2 0.0 2.6e-20 73.2 0.0 1.5 1 1 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Glycos_transf_1 PF00534.20 EKX35197.1 - 1.6e-05 24.5 0.2 0.004 16.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Pkinase PF00069.25 EKX35198.1 - 1.5e-37 129.4 0.0 1.8e-37 129.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX35198.1 - 5e-18 65.3 0.0 6.5e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX35198.1 - 0.0037 17.2 0.0 0.0055 16.7 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EKX35198.1 - 0.015 14.9 0.0 0.028 14.0 0.0 1.5 1 1 1 2 2 2 0 RIO1 family CEP76-C2 PF15627.6 EKX35199.1 - 1.3e-30 106.0 0.0 2.2e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 CEP76 C2 domain EnY2 PF10163.9 EKX35199.1 - 0.042 14.2 0.3 0.14 12.6 0.3 1.9 1 0 0 1 1 1 0 Transcription factor e(y)2 MobL PF18555.1 EKX35199.1 - 0.15 11.3 0.5 0.85 8.8 0.1 2.0 2 0 0 2 2 2 0 MobL relaxases PALP PF00291.25 EKX35200.1 - 1.3e-67 228.3 0.2 1.5e-67 228.1 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 EKX35200.1 - 0.00063 19.7 0.2 0.025 14.5 0.1 2.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase DFP PF04127.15 EKX35200.1 - 0.033 14.0 0.1 0.11 12.3 0.1 1.9 1 1 1 2 2 2 0 DNA / pantothenate metabolism flavoprotein DUF3798 PF12683.7 EKX35200.1 - 0.066 12.6 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) LRR_6 PF13516.6 EKX35202.1 - 5.1e-23 79.1 4.4 2e-06 27.4 0.1 5.5 5 0 0 5 5 5 5 Leucine Rich repeat LRR_4 PF12799.7 EKX35202.1 - 1.9e-10 40.8 4.3 9e-05 22.8 1.9 3.6 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX35202.1 - 1.8e-06 27.6 7.4 0.0045 16.7 3.5 4.0 2 2 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 EKX35202.1 - 1.1e-05 25.3 5.7 10 7.1 0.5 5.4 4 1 1 5 5 5 2 Leucine Rich Repeat EBA-175_VI PF11556.8 EKX35203.1 - 0.078 13.3 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 Erythrocyte binding antigen 175 Arm PF00514.23 EKX35204.1 - 1e-27 95.2 7.4 0.0021 18.1 0.1 9.2 9 0 0 9 9 9 6 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EKX35204.1 - 7.7e-07 29.1 5.8 0.31 11.1 0.1 5.6 2 2 3 5 5 5 2 Spinocerebellar ataxia type 10 protein domain KAP PF05804.12 EKX35204.1 - 0.00033 18.9 0.1 0.013 13.7 0.0 2.3 2 1 0 2 2 2 1 Kinesin-associated protein (KAP) HEAT_EZ PF13513.6 EKX35204.1 - 0.0015 19.0 0.4 15 6.2 0.0 4.7 4 1 1 5 5 5 1 HEAT-like repeat DUF3361 PF11841.8 EKX35204.1 - 0.0018 18.2 0.5 3.9 7.4 0.0 4.0 4 1 1 5 5 5 1 Domain of unknown function (DUF3361) Arm_2 PF04826.13 EKX35204.1 - 0.015 14.8 0.5 1.3 8.5 0.1 3.5 3 1 0 4 4 4 0 Armadillo-like DUF383 PF04063.14 EKX35204.1 - 0.024 14.3 1.2 0.61 9.7 0.5 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF383) HEAT PF02985.22 EKX35204.1 - 1.7 9.1 6.3 18 6.0 0.0 5.2 6 0 0 6 6 6 0 HEAT repeat TPR_1 PF00515.28 EKX35205.1 - 2.8e-06 26.9 9.9 0.0064 16.3 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX35205.1 - 1.4e-05 24.8 0.1 1.4e-05 24.8 0.1 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX35205.1 - 0.00059 19.7 0.0 0.00059 19.7 0.0 4.9 5 2 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX35205.1 - 0.027 14.6 0.3 0.027 14.6 0.3 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX35205.1 - 0.65 10.4 15.6 1.2 9.5 1.4 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat RWP-RK PF02042.15 EKX35207.1 - 1.2e-06 28.4 0.0 2.6e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 RWP-RK domain AC_N PF16214.5 EKX35207.1 - 0.095 11.8 0.3 0.09 11.9 0.3 1.0 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region LpxC PF03331.13 EKX35207.1 - 0.099 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 UDP-3-O-acyl N-acetylglycosamine deacetylase DUF5549 PF17703.1 EKX35207.1 - 0.13 11.9 0.3 0.16 11.6 0.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5549) FG-GAP_2 PF14312.6 EKX35208.1 - 0.037 14.3 6.9 0.26 11.6 1.2 3.4 4 0 0 4 4 4 0 FG-GAP repeat CinA PF02464.17 EKX35208.1 - 0.33 10.5 4.3 0.36 10.4 0.8 2.3 2 0 0 2 2 2 0 Competence-damaged protein Ephrin_rec_like PF07699.13 EKX35209.1 - 1.1e-11 44.3 95.1 0.018 14.8 2.1 9.8 7 2 3 10 10 10 9 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX35209.1 - 1.9e-05 25.0 72.7 0.045 14.2 4.4 10.1 7 3 1 9 9 9 6 TNFR/NGFR cysteine-rich region Pox_Ag35 PF03286.14 EKX35211.1 - 0.0032 17.3 12.9 0.0032 17.3 12.9 2.2 2 0 0 2 2 2 1 Pox virus Ag35 surface protein BUD22 PF09073.10 EKX35211.1 - 0.0072 15.7 40.3 0.0096 15.3 40.3 1.1 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 EKX35211.1 - 0.055 11.7 37.1 0.078 11.2 37.1 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EKX35211.1 - 3.9 6.8 44.2 6.5 6.1 44.2 1.3 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 EKX35211.1 - 4.7 5.9 13.3 6.2 5.5 13.3 1.2 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 EKX35211.1 - 9.2 4.2 11.6 10 4.1 11.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein V-ATPase_H_N PF03224.14 EKX35212.1 - 3.6e-52 177.6 1.9 4e-52 177.5 1.9 1.0 1 0 0 1 1 1 1 V-ATPase subunit H Imm49 PF15575.6 EKX35212.1 - 0.0042 16.9 0.4 0.0068 16.2 0.4 1.5 1 0 0 1 1 1 1 Immunity protein 49 Arm PF00514.23 EKX35212.1 - 0.0051 16.8 0.1 0.2 11.8 0.0 3.3 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat IBN_N PF03810.19 EKX35213.1 - 1.6e-13 50.3 0.1 7.8e-13 48.1 0.1 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EKX35213.1 - 1.1e-10 41.8 0.0 3.7e-06 27.1 0.0 4.8 3 1 1 4 4 4 1 Exportin 1-like protein Cse1 PF08506.10 EKX35213.1 - 0.00044 19.2 0.0 0.0069 15.2 0.0 2.6 3 0 0 3 3 3 1 Cse1 HEAT PF02985.22 EKX35213.1 - 0.0035 17.5 9.4 2 8.9 0.0 6.9 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.6 EKX35213.1 - 0.023 15.2 8.0 4 8.1 0.1 5.7 7 0 0 7 7 7 0 HEAT-like repeat DUF3437 PF11919.8 EKX35213.1 - 0.041 13.8 1.5 3.1 7.8 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3437) Inhibitor_G39P PF11417.8 EKX35213.1 - 0.12 12.9 0.1 0.4 11.2 0.1 1.9 1 0 0 1 1 1 0 Loader and inhibitor of phage G40P GalKase_gal_bdg PF10509.9 EKX35214.1 - 1.2e-18 66.3 0.1 2.2e-18 65.6 0.1 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 EKX35214.1 - 1.3e-14 54.1 0.5 2.9e-14 53.0 0.5 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EKX35214.1 - 5.2e-13 49.2 0.0 1.2e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Sec3_C PF09763.9 EKX35216.1 - 3.2e-08 32.5 0.1 3.2e-08 32.5 0.1 3.4 4 0 0 4 4 3 2 Exocyst complex component Sec3 Atg8 PF02991.16 EKX35216.1 - 4.9e-08 33.1 0.0 0.0018 18.4 0.0 2.6 2 0 0 2 2 2 2 Autophagy protein Atg8 ubiquitin like DUF2457 PF10446.9 EKX35216.1 - 0.047 12.8 36.8 0.086 12.0 9.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Pox_Ag35 PF03286.14 EKX35216.1 - 0.67 9.7 30.0 1.2 8.9 11.8 4.0 4 0 0 4 4 4 0 Pox virus Ag35 surface protein SDA1 PF05285.12 EKX35216.1 - 1.5 8.2 36.6 0.03 13.8 28.4 2.2 2 0 0 2 2 2 0 SDA1 SpoIIP PF07454.11 EKX35216.1 - 1.9 7.8 9.7 1.4 8.4 1.6 2.4 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 EKX35216.1 - 3.4 6.3 14.4 9.1 4.9 14.4 1.7 1 0 0 1 1 1 0 Presenilin PPP4R2 PF09184.11 EKX35216.1 - 3.8 7.0 34.0 0.4 10.2 7.4 2.6 2 0 0 2 2 2 0 PPP4R2 NOA36 PF06524.12 EKX35216.1 - 7.7 5.7 39.2 1.5 8.1 13.5 2.7 2 0 0 2 2 2 0 NOA36 protein MAM33 PF02330.16 EKX35216.1 - 8.2 6.3 17.1 5.7 6.8 4.8 2.5 2 0 0 2 2 2 0 Mitochondrial glycoprotein SAPS PF04499.15 EKX35216.1 - 8.9 5.0 14.5 0.36 9.6 7.7 2.1 2 1 1 3 3 3 0 SIT4 phosphatase-associated protein DUF3456 PF11938.8 EKX35217.1 - 8.6e-05 23.1 5.5 0.046 14.2 5.5 3.0 1 1 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP TPR_8 PF13181.6 EKX35220.1 - 0.00015 21.7 0.0 0.00047 20.2 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX35220.1 - 0.0078 16.2 0.0 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX35220.1 - 0.0089 15.8 0.1 0.021 14.6 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat IQ PF00612.27 EKX35220.1 - 0.015 15.0 1.5 0.046 13.5 1.5 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif PB1 PF00564.24 EKX35220.1 - 0.036 14.0 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 PB1 domain CAP_N PF01213.19 EKX35220.1 - 0.82 9.1 3.5 1.4 8.3 3.5 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal YtxH PF12732.7 EKX35221.1 - 0.16 12.5 1.1 6.7 7.3 0.5 3.0 2 1 1 3 3 3 0 YtxH-like protein FUSC PF04632.12 EKX35221.1 - 4 5.9 7.3 7.7 4.9 7.3 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family TetR_C_13 PF16925.5 EKX35221.1 - 9.8 6.1 7.2 1.4 8.8 2.4 2.2 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Rep_fac-A_C PF08646.10 EKX35222.1 - 4.3e-31 107.6 0.9 4.3e-31 107.6 0.9 3.1 4 0 0 4 4 4 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EKX35222.1 - 1.7e-28 98.4 5.7 8.5e-27 93.0 0.8 2.9 3 0 0 3 3 3 2 Replication protein A OB domain tRNA_anti-codon PF01336.25 EKX35222.1 - 8.9e-08 32.0 1.3 0.00015 21.7 0.1 3.5 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain DUF223 PF02721.14 EKX35222.1 - 0.00069 19.9 0.8 0.016 15.5 0.1 3.1 3 0 0 3 3 3 1 Domain of unknown function DUF223 CDC24_OB3 PF17244.2 EKX35222.1 - 0.00083 19.1 0.9 0.63 9.7 0.1 2.9 3 0 0 3 3 3 2 Cell division control protein 24, OB domain 3 MGDG_synth PF06925.11 EKX35222.1 - 0.06 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase Reticulon PF02453.17 EKX35223.1 - 4.2e-27 95.0 3.3 5.3e-27 94.7 3.3 1.1 1 0 0 1 1 1 1 Reticulon Peptidase_S49_N PF08496.10 EKX35223.1 - 0.0065 16.5 0.8 0.0065 16.5 0.8 1.8 2 0 0 2 2 2 1 Peptidase family S49 N-terminal DUF273 PF03314.14 EKX35224.1 - 3.7e-33 114.9 0.2 4.7e-33 114.6 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Glyco_transf_34 PF05637.12 EKX35224.1 - 0.043 13.5 0.4 3.8 7.2 0.2 2.1 1 1 1 2 2 2 0 galactosyl transferase GMA12/MNN10 family ECR1_N PF14382.6 EKX35226.1 - 4.4e-15 55.2 0.3 1e-14 54.1 0.3 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 EKX35226.1 - 7.4e-05 23.0 0.0 0.00025 21.4 0.0 1.9 1 1 0 1 1 1 1 KH domain EXOSC1 PF10447.9 EKX35226.1 - 0.033 14.8 0.3 0.58 10.8 0.3 2.2 1 1 1 2 2 2 0 Exosome component EXOSC1/CSL4 cNMP_binding PF00027.29 EKX35227.1 - 3e-16 59.3 0.1 5.5e-16 58.4 0.1 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain EF-hand_7 PF13499.6 EKX35227.1 - 8.1e-08 32.6 2.4 2e-07 31.4 0.9 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX35227.1 - 1.2e-07 31.1 1.2 0.00022 20.9 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EKX35227.1 - 4e-07 29.1 2.6 0.0079 15.7 0.1 3.0 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX35227.1 - 5.1e-05 23.0 2.1 0.0012 18.7 0.3 3.3 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX35227.1 - 0.00067 19.0 4.1 0.12 11.9 0.1 3.3 3 0 0 3 3 3 2 EF hand GREB1 PF15782.5 EKX35227.1 - 2 5.4 9.3 3.5 4.6 9.3 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer MORN PF02493.20 EKX35228.1 - 2e-22 77.7 25.1 2.2e-06 27.2 1.5 5.2 5 0 0 5 5 5 5 MORN repeat Ank_4 PF13637.6 EKX35229.1 - 1.5e-18 66.9 1.2 3.8e-10 40.1 0.2 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX35229.1 - 1.2e-16 60.6 0.1 2.2e-11 43.7 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX35229.1 - 3.3e-14 53.2 0.2 2.1e-07 31.4 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EKX35229.1 - 6.3e-13 48.5 1.5 8.2e-05 22.9 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EKX35229.1 - 5.6e-12 44.7 0.8 3.6e-05 23.8 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeat Acylphosphatase PF00708.18 EKX35230.1 - 0.0088 16.4 0.0 0.022 15.1 0.0 1.7 1 0 0 1 1 1 1 Acylphosphatase DUF1133 PF06576.11 EKX35230.1 - 0.046 13.1 0.1 0.1 12.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1133) CUB PF00431.20 EKX35231.1 - 1.7e-07 31.5 0.0 3e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 CUB domain PDCD7 PF16021.5 EKX35231.1 - 0.5 9.4 14.4 0.11 11.6 6.8 2.2 2 0 0 2 2 2 0 Programmed cell death protein 7 C2 PF00168.30 EKX35232.1 - 1.7e-15 57.2 0.0 6.9e-15 55.2 0.0 2.1 2 0 0 2 2 2 1 C2 domain Ion_trans_2 PF07885.16 EKX35232.1 - 6.7e-09 35.6 4.0 6.7e-09 35.6 4.0 2.1 3 0 0 3 3 3 1 Ion channel cNMP_binding PF00027.29 EKX35232.1 - 2.1e-08 34.1 0.0 0.00056 19.9 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ion_trans PF00520.31 EKX35232.1 - 0.00034 19.9 10.0 0.00034 19.9 10.0 2.3 2 1 0 2 2 2 1 Ion transport protein bZIP_1 PF00170.21 EKX35232.1 - 0.0042 17.2 4.0 0.012 15.7 4.0 1.7 1 0 0 1 1 1 1 bZIP transcription factor DUF3584 PF12128.8 EKX35232.1 - 0.04 11.4 2.9 0.067 10.7 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF724 PF05266.14 EKX35232.1 - 0.041 13.7 1.3 0.11 12.3 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF724) FlxA PF14282.6 EKX35232.1 - 0.061 13.3 0.2 0.14 12.2 0.2 1.5 1 0 0 1 1 1 0 FlxA-like protein Syntaxin_2 PF14523.6 EKX35232.1 - 0.22 11.9 2.2 0.3 11.5 0.6 2.1 2 0 0 2 2 2 0 Syntaxin-like protein CENP-H PF05837.12 EKX35232.1 - 1.3 9.5 7.2 0.27 11.7 2.4 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) 3-HAO PF06052.12 EKX35234.1 - 1e-49 168.0 0.2 1.3e-49 167.8 0.2 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase AraC_binding PF02311.19 EKX35234.1 - 3.9e-05 23.6 0.0 7.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_2 PF07883.11 EKX35234.1 - 0.00076 19.1 0.1 0.00076 19.1 0.1 1.5 2 0 0 2 2 2 1 Cupin domain UMPH-1 PF05822.12 EKX35235.1 - 9.7e-79 264.4 0.0 1.1e-78 264.1 0.0 1.0 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 EKX35235.1 - 2.5e-07 31.3 0.1 6.3e-07 30.0 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EKX35235.1 - 0.024 14.9 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase GSH-S_ATP PF02955.16 EKX35236.1 - 9.8e-05 21.8 0.0 0.00022 20.7 0.0 1.5 2 0 0 2 2 2 1 Prokaryotic glutathione synthetase, ATP-grasp domain RimK PF08443.11 EKX35236.1 - 0.0094 15.6 0.0 0.64 9.6 0.0 2.2 2 0 0 2 2 2 2 RimK-like ATP-grasp domain cNMP_binding PF00027.29 EKX35238.1 - 7.2e-11 42.0 0.0 1.6e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EKX35238.1 - 2.7e-10 40.0 3.8 4.4e-10 39.4 3.8 1.4 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EKX35238.1 - 0.00018 20.8 0.9 0.00027 20.2 0.9 1.2 1 0 0 1 1 1 1 Ion transport protein UPF0147 PF03685.13 EKX35238.1 - 0.28 11.2 1.9 12 6.1 0.1 3.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0147) CD20 PF04103.15 EKX35239.1 - 0.00058 20.0 15.1 0.0021 18.1 15.0 1.8 1 1 0 1 1 1 1 CD20-like family PAP2_3 PF14378.6 EKX35239.1 - 0.0054 16.5 1.6 0.0088 15.8 1.6 1.4 1 0 0 1 1 1 1 PAP2 superfamily Bax1-I PF01027.20 EKX35239.1 - 0.015 15.1 10.4 0.027 14.3 10.4 1.3 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF1218 PF06749.12 EKX35239.1 - 0.027 15.0 13.2 1.4 9.5 3.3 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF1218) EIID-AGA PF03613.14 EKX35239.1 - 0.041 13.0 0.4 0.041 13.0 0.4 1.6 2 0 0 2 2 2 0 PTS system mannose/fructose/sorbose family IID component DUF4064 PF13273.6 EKX35239.1 - 0.62 10.4 13.0 0.76 10.1 8.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) TcdA_TcdB_pore PF12920.7 EKX35239.1 - 2.9 6.0 5.4 4.2 5.5 5.4 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain PGPGW PF09656.10 EKX35239.1 - 3.7 7.1 11.4 2.8 7.5 1.6 2.7 2 0 0 2 2 2 0 Putative transmembrane protein (PGPGW) DUF3040 PF11239.8 EKX35239.1 - 7 7.0 17.0 4.5 7.6 0.4 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3040) Tetraspanin PF00335.20 EKX35239.1 - 9.7 5.8 19.0 0.11 12.1 4.2 2.2 1 1 1 2 2 2 0 Tetraspanin family Peptidase_M28 PF04389.17 EKX35240.1 - 1.3e-14 54.3 0.0 2.1e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.15 EKX35240.1 - 4.5e-05 23.0 0.4 0.00064 19.3 0.4 2.3 1 1 0 1 1 1 1 Nicastrin Peptidase_M41 PF01434.18 EKX35241.1 - 8.3e-68 228.0 0.0 1.3e-67 227.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EKX35241.1 - 1.1e-40 139.1 0.0 6.1e-40 136.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EKX35241.1 - 6.2e-12 45.1 3.3 6.2e-12 45.1 1.1 2.1 2 0 0 2 2 2 1 AAA+ lid domain FtsH_ext PF06480.15 EKX35241.1 - 5.2e-10 39.7 2.2 6.7e-10 39.3 0.0 2.3 3 0 0 3 3 1 1 FtsH Extracellular AAA_5 PF07728.14 EKX35241.1 - 0.0005 20.1 0.0 0.0017 18.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EKX35241.1 - 0.00085 18.6 0.0 0.0016 17.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 EKX35241.1 - 0.0011 19.2 0.3 0.053 13.8 0.1 2.9 2 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EKX35241.1 - 0.0073 16.1 0.1 0.017 14.9 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein RuvB_N PF05496.12 EKX35241.1 - 0.0073 16.1 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EKX35241.1 - 0.02 14.3 0.4 0.064 12.6 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EKX35241.1 - 0.037 14.3 0.2 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EKX35241.1 - 0.062 13.7 0.1 1 9.7 0.1 2.7 2 1 0 3 3 2 0 AAA ATPase domain AAA_18 PF13238.6 EKX35241.1 - 0.071 13.6 0.0 0.24 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EKX35241.1 - 0.072 13.3 0.2 0.22 11.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.6 EKX35241.1 - 0.079 13.4 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 EKX35241.1 - 0.081 13.0 0.0 0.3 11.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF2854 PF11016.8 EKX35241.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) AAA_7 PF12775.7 EKX35241.1 - 0.19 11.2 0.1 0.51 9.8 0.1 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region zf-C3HC4 PF00097.25 EKX35242.1 - 6.5e-05 22.7 7.1 0.00015 21.6 7.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX35242.1 - 0.00018 21.4 6.1 0.00041 20.3 6.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EKX35242.1 - 0.0013 19.0 12.9 0.0087 16.4 12.9 2.3 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EKX35242.1 - 0.0013 18.6 9.3 0.0039 17.1 9.3 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EKX35242.1 - 0.0031 17.3 8.5 0.0031 17.3 8.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zinc-ribbons_6 PF07191.12 EKX35242.1 - 0.022 14.7 7.3 0.53 10.3 6.5 2.2 1 1 1 2 2 2 0 zinc-ribbons zf-ribbon_3 PF13248.6 EKX35242.1 - 0.024 14.0 2.9 0.086 12.3 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain DUF1178 PF06676.11 EKX35242.1 - 0.053 13.9 0.5 0.19 12.1 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1178) NOB1_Zn_bind PF08772.11 EKX35242.1 - 0.056 13.6 6.9 5.7 7.2 0.0 2.7 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-C3HC4_3 PF13920.6 EKX35242.1 - 0.098 12.5 12.6 0.8 9.6 12.6 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EKX35242.1 - 0.099 12.8 10.4 0.88 9.8 10.4 2.4 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING OrfB_Zn_ribbon PF07282.11 EKX35242.1 - 1.1 9.3 5.4 4.6 7.2 0.1 2.7 2 1 1 3 3 3 0 Putative transposase DNA-binding domain HypA PF01155.19 EKX35242.1 - 2.1 8.4 6.7 3.8 7.6 4.8 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Wax2_C PF12076.8 EKX35243.1 - 2.9e-53 179.9 0.0 4.2e-53 179.4 0.0 1.2 1 0 0 1 1 1 1 WAX2 C-terminal domain FA_hydroxylase PF04116.13 EKX35243.1 - 0.0015 18.9 7.0 0.0015 18.9 7.0 2.5 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily adh_short PF00106.25 EKX35243.1 - 0.0035 16.8 0.0 0.0051 16.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase STT3 PF02516.14 EKX35244.1 - 2.1e-58 198.5 33.5 1.3e-52 179.4 29.2 3.0 2 1 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Ank_2 PF12796.7 EKX35244.1 - 5.6e-06 26.9 0.0 3.8e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) BSD PF03909.17 EKX35245.1 - 0.16 12.0 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 BSD domain SRP_SPB PF02978.19 EKX35246.1 - 1.4e-07 32.1 0.1 4.8e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 Signal peptide binding domain cNMP_binding PF00027.29 EKX35247.1 - 1.1e-22 79.9 0.3 1.3e-12 47.6 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain ELYS-bb PF16687.5 EKX35248.1 - 0.02 13.5 0.2 0.032 12.9 0.2 1.2 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin YabA PF06156.13 EKX35248.1 - 0.026 15.2 5.0 0.026 15.2 5.0 2.5 2 1 0 2 2 2 0 Initiation control protein YabA PDH PF02153.17 EKX35248.1 - 0.037 13.0 0.0 0.065 12.2 0.0 1.4 1 0 0 1 1 1 0 Prephenate dehydrogenase IQ PF00612.27 EKX35248.1 - 0.093 12.6 0.3 0.27 11.1 0.3 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF5082 PF16888.5 EKX35248.1 - 2 8.7 9.0 0.21 11.9 3.3 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) FUSC PF04632.12 EKX35248.1 - 2.1 6.8 3.5 3 6.3 3.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family PBP_like_2 PF12849.7 EKX35250.1 - 2.9e-32 112.5 0.0 3.8e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 PBP superfamily domain PBP_like PF12727.7 EKX35250.1 - 1e-05 24.8 0.1 4.2e-05 22.8 0.1 1.8 1 1 0 1 1 1 1 PBP superfamily domain WD40 PF00400.32 EKX35251.1 - 7.5e-22 77.2 14.2 5.8e-06 26.9 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX35251.1 - 1.3e-06 28.7 0.1 0.11 12.8 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain HicB_lk_antitox PF15919.5 EKX35251.1 - 0.16 12.1 1.1 0.31 11.2 1.1 1.4 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system PRCC PF10253.9 EKX35251.1 - 3.2 8.5 8.3 6.4 7.5 8.3 1.4 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting HTH_29 PF13551.6 EKX35252.1 - 0.05 13.6 10.4 12 6.0 0.2 4.6 3 1 1 4 4 4 0 Winged helix-turn helix HTH_23 PF13384.6 EKX35252.1 - 0.96 9.3 5.4 76 3.3 0.0 3.8 4 0 0 4 4 4 0 Homeodomain-like domain DEAD PF00270.29 EKX35253.1 - 8.3e-46 155.9 0.0 1.3e-45 155.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX35253.1 - 6e-32 110.3 0.0 2.9e-31 108.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HEM4 PF02602.15 EKX35253.1 - 0.01 15.2 0.1 0.022 14.1 0.1 1.5 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD ResIII PF04851.15 EKX35253.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EKX35253.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Pkinase PF00069.25 EKX35254.1 - 6.5e-68 229.0 0.0 7.6e-68 228.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX35254.1 - 5.1e-34 117.7 0.0 6.6e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EKX35254.1 - 9.9e-05 21.4 0.0 0.00014 20.9 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EKX35254.1 - 0.024 14.6 0.1 0.047 13.6 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EKX35254.1 - 0.04 13.5 0.1 0.26 10.9 0.1 1.9 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EKX35254.1 - 0.045 13.1 0.0 0.33 10.2 0.0 2.0 1 1 1 2 2 2 0 Kinase-like Kdo PF06293.14 EKX35254.1 - 0.056 12.8 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CNH PF00780.22 EKX35255.1 - 0.0086 15.7 0.1 0.31 10.6 0.0 2.5 2 1 0 2 2 2 1 CNH domain Nop14 PF04147.12 EKX35255.1 - 0.093 10.9 23.9 0.13 10.4 23.9 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EKX35255.1 - 0.33 10.3 27.2 0.55 9.6 27.2 1.2 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 EKX35255.1 - 1.1 7.9 2.8 0.42 9.3 0.5 1.5 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Mpp10 PF04006.12 EKX35255.1 - 7.4 4.9 18.8 11 4.3 18.8 1.2 1 0 0 1 1 1 0 Mpp10 protein Mg_trans_NIPA PF05653.14 EKX35256.1 - 4.8e-18 65.3 2.3 5.6e-18 65.1 2.3 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA CENP-B_dimeris PF09026.10 EKX35256.1 - 0.018 15.4 9.2 0.026 14.9 9.2 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 EKX35256.1 - 0.025 12.7 8.4 0.028 12.5 8.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi GSK-3_bind PF05350.12 EKX35256.1 - 0.072 12.4 0.8 0.12 11.7 0.8 1.3 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding DUF2457 PF10446.9 EKX35256.1 - 0.099 11.8 11.2 0.12 11.6 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 EKX35256.1 - 0.13 10.5 8.6 0.12 10.5 8.6 1.0 1 0 0 1 1 1 0 Nop14-like family Radial_spoke PF04712.12 EKX35256.1 - 0.14 11.1 3.7 0.074 12.0 1.9 1.4 2 0 0 2 2 2 0 Radial spokehead-like protein Vfa1 PF08432.10 EKX35256.1 - 0.16 12.3 4.2 0.18 12.1 4.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RPN2_C PF18004.1 EKX35256.1 - 0.19 11.7 4.9 0.23 11.4 4.9 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Cwf_Cwc_15 PF04889.12 EKX35256.1 - 0.2 11.4 13.9 0.24 11.1 13.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RRN3 PF05327.11 EKX35256.1 - 0.23 9.9 3.5 0.25 9.8 3.5 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 FAM176 PF14851.6 EKX35256.1 - 0.26 10.9 4.1 0.4 10.3 4.1 1.4 1 0 0 1 1 1 0 FAM176 family DUF4666 PF15697.5 EKX35256.1 - 0.32 11.7 2.6 0.44 11.3 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4666) TRAP_alpha PF03896.16 EKX35256.1 - 0.62 9.2 3.4 0.77 8.9 3.4 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.12 EKX35256.1 - 0.99 8.7 12.0 1.2 8.4 12.0 1.1 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 EKX35256.1 - 1 9.8 13.3 0.99 9.8 12.0 1.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal U79_P34 PF03064.16 EKX35256.1 - 5.4 6.3 11.1 6.9 6.0 11.1 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 UbiA PF01040.18 EKX35257.1 - 3.3e-34 118.3 10.6 3.3e-34 118.3 10.6 1.6 1 1 0 1 1 1 1 UbiA prenyltransferase family UCH PF00443.29 EKX35258.1 - 7.8e-52 176.3 0.1 9.2e-52 176.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EKX35258.1 - 1.1e-23 84.3 0.2 1.5e-23 83.9 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Fra10Ac1 PF09725.9 EKX35258.1 - 0.042 13.9 0.2 0.077 13.1 0.2 1.4 1 0 0 1 1 1 0 Folate-sensitive fragile site protein Fra10Ac1 Peptidase_C98 PF15499.6 EKX35258.1 - 0.11 12.0 4.9 0.51 9.8 0.1 2.7 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF3951 PF13131.6 EKX35259.1 - 0.37 11.0 5.1 0.54 10.5 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) PhzC-PhzF PF02567.16 EKX35260.1 - 1e-50 172.8 0.0 1.5e-50 172.3 0.0 1.2 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein DAP_epimerase PF01678.19 EKX35260.1 - 0.0026 17.9 0.1 0.0071 16.5 0.1 1.7 1 0 0 1 1 1 1 Diaminopimelate epimerase PDZ PF00595.24 EKX35261.1 - 5.9e-32 109.9 0.9 6.7e-09 36.0 0.0 4.4 3 1 1 4 4 4 3 PDZ domain PDZ_6 PF17820.1 EKX35261.1 - 1.1e-28 98.8 1.1 8.2e-08 32.0 0.0 4.3 4 0 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 EKX35261.1 - 2.7e-18 66.1 0.1 0.00097 19.4 0.0 4.3 4 0 0 4 4 4 4 PDZ domain Tricorn_PDZ PF14685.6 EKX35261.1 - 8.7e-11 41.6 0.0 0.047 13.7 0.0 4.3 4 0 0 4 4 4 3 Tricorn protease PDZ domain PseudoU_synth_2 PF00849.22 EKX35263.1 - 1.2e-16 61.2 0.0 2.1e-16 60.4 0.0 1.4 2 0 0 2 2 2 1 RNA pseudouridylate synthase PDZ_6 PF17820.1 EKX35264.1 - 4.9e-22 77.5 0.4 5e-09 35.9 0.0 3.5 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.24 EKX35264.1 - 2.2e-19 69.6 0.1 4.6e-08 33.3 0.1 3.4 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 EKX35264.1 - 1.6e-12 47.6 0.0 0.00011 22.5 0.0 3.6 3 0 0 3 3 3 3 PDZ domain Tricorn_PDZ PF14685.6 EKX35264.1 - 3.7e-07 30.0 0.0 0.36 10.8 0.0 3.5 3 1 0 3 3 3 3 Tricorn protease PDZ domain DUF3432 PF11914.8 EKX35264.1 - 0.00067 19.9 7.3 0.0044 17.2 1.0 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF3432) Cuticle_3 PF11018.8 EKX35264.1 - 0.85 9.8 13.7 1.6 8.9 13.7 1.4 1 0 0 1 1 1 0 Pupal cuticle protein C1 SPRY PF00622.28 EKX35265.1 - 3.8e-09 36.7 0.0 0.00011 22.3 0.0 2.5 2 0 0 2 2 2 2 SPRY domain Mac-1 PF09028.10 EKX35265.1 - 0.083 11.9 0.1 0.25 10.4 0.0 1.7 2 0 0 2 2 2 0 Mac 1 DUF3137 PF11335.8 EKX35265.1 - 0.14 12.1 0.2 0.27 11.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3137) Pkinase PF00069.25 EKX35266.1 - 1.6e-47 162.1 0.0 2.1e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX35266.1 - 2.8e-31 108.7 0.0 3.6e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX35266.1 - 9.4e-05 21.9 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EKX35266.1 - 0.00012 21.0 0.0 0.0002 20.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EKX35266.1 - 0.00016 21.1 0.2 0.00022 20.6 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX35266.1 - 0.0064 16.4 0.9 0.15 11.9 0.1 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EKX35266.1 - 0.022 14.3 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 EKX35266.1 - 0.11 12.1 0.2 0.45 10.1 0.2 1.9 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Hexapep PF00132.24 EKX35268.1 - 9.9e-14 50.4 16.4 2.8e-05 23.6 1.7 4.3 1 1 4 5 5 5 5 Bacterial transferase hexapeptide (six repeats) W2 PF02020.18 EKX35268.1 - 1.7e-13 50.5 4.9 1.7e-13 50.5 4.9 2.3 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Fucokinase PF07959.12 EKX35268.1 - 1e-05 24.7 0.3 4.9e-05 22.4 0.3 1.8 1 1 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 EKX35268.1 - 8.9e-05 20.8 4.6 0.00013 20.3 1.3 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4954) YkuI_C PF10388.9 EKX35268.1 - 0.06 13.1 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 EAL-domain associated signalling protein domain Hexapep_2 PF14602.6 EKX35268.1 - 0.071 12.9 18.3 0.31 10.8 0.8 3.7 1 1 2 3 3 3 0 Hexapeptide repeat of succinyl-transferase Aldo_ket_red PF00248.21 EKX35269.1 - 5.9e-72 242.3 0.0 6.6e-72 242.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hydrolase_4 PF12146.8 EKX35270.1 - 2.9e-13 49.6 0.0 1.5e-09 37.5 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EKX35270.1 - 4.3e-10 40.6 0.2 3.3e-09 37.7 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EKX35270.1 - 9e-07 28.8 0.0 0.00015 21.5 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EKX35270.1 - 7.1e-06 25.6 0.0 0.025 14.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EKX35270.1 - 1.4e-05 25.0 0.0 0.0085 15.9 0.0 2.9 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase DUF1749 PF08538.10 EKX35270.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Mob1_phocein PF03637.17 EKX35271.1 - 3.6e-80 267.9 0.0 4.3e-80 267.7 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family DUF724 PF05266.14 EKX35272.1 - 0.74 9.6 6.8 1.2 8.9 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) EMC3_TMCO1 PF01956.16 EKX35272.1 - 1.8 8.3 4.9 0.88 9.3 0.1 2.4 3 0 0 3 3 3 0 Integral membrane protein EMC3/TMCO1-like TPR_9 PF13371.6 EKX35273.1 - 0.00028 21.0 0.5 0.0028 17.8 1.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX35273.1 - 0.00061 19.7 5.1 0.0018 18.2 0.2 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX35273.1 - 0.0077 16.0 0.7 0.025 14.4 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat FKBP_C PF00254.28 EKX35273.1 - 0.018 15.3 0.0 0.16 12.3 0.0 2.6 2 1 0 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_6 PF13174.6 EKX35273.1 - 0.31 11.8 2.5 10 7.0 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX35273.1 - 0.33 11.9 4.0 0.53 11.2 0.6 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX35273.1 - 4.4 7.9 6.1 22 5.7 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat NADH-u_ox-rdase PF10785.9 EKX35274.1 - 1.3e-19 70.7 0.1 1.4e-19 70.5 0.1 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF2960 PF11173.8 EKX35274.1 - 0.15 12.5 0.1 0.21 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) Ion_trans PF00520.31 EKX35276.1 - 3e-22 79.0 17.5 4.1e-22 78.6 9.8 2.2 1 1 1 2 2 2 2 Ion transport protein Ion_trans_2 PF07885.16 EKX35276.1 - 1.9e-11 43.8 6.0 1.9e-11 43.8 6.0 2.9 3 0 0 3 3 3 1 Ion channel cNMP_binding PF00027.29 EKX35276.1 - 1.2e-10 41.3 0.0 2.6e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Mpv17_PMP22 PF04117.12 EKX35278.1 - 3.1e-19 69.0 5.4 3.1e-19 69.0 5.4 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family Sec7_N PF12783.7 EKX35278.1 - 0.098 12.6 0.2 0.55 10.1 0.2 1.9 1 1 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal REF PF05755.12 EKX35279.1 - 0.096 12.5 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) HydF_tetramer PF18133.1 EKX35280.1 - 0.053 13.3 0.1 6.6 6.5 0.1 2.4 2 0 0 2 2 2 0 Hydrogen maturase F tetramerization domain TPR_1 PF00515.28 EKX35281.1 - 9.6e-42 139.2 34.1 7.2e-06 25.6 0.4 14.2 17 0 0 17 17 15 8 Tetratricopeptide repeat TPR_2 PF07719.17 EKX35281.1 - 4.6e-36 120.0 30.3 0.00065 19.6 0.2 15.3 16 0 0 16 16 15 8 Tetratricopeptide repeat TPR_8 PF13181.6 EKX35281.1 - 3.9e-35 117.1 20.6 1.4e-05 24.9 0.3 13.5 16 0 0 16 16 13 6 Tetratricopeptide repeat TPR_14 PF13428.6 EKX35281.1 - 4.5e-34 114.2 1.5 0.0013 19.3 0.0 13.0 9 3 5 14 14 13 6 Tetratricopeptide repeat TPR_19 PF14559.6 EKX35281.1 - 3.4e-33 114.0 5.6 0.00058 20.3 0.0 12.0 6 3 6 13 13 13 9 Tetratricopeptide repeat TPR_16 PF13432.6 EKX35281.1 - 4.1e-22 78.5 0.1 3.7e-05 24.3 0.1 8.8 9 1 1 10 10 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 EKX35281.1 - 1e-20 73.8 30.4 2.3e-06 27.8 0.2 11.8 8 6 5 14 14 14 4 Tetratricopeptide repeat TPR_6 PF13174.6 EKX35281.1 - 1.1e-16 60.3 21.1 0.11 13.2 0.4 12.7 14 1 0 14 14 13 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX35281.1 - 6e-16 57.2 15.8 3.7e-05 23.4 0.0 11.5 14 0 0 14 14 11 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX35281.1 - 1.4e-14 53.3 24.5 0.081 13.3 0.0 13.5 14 1 1 15 15 14 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX35281.1 - 2e-14 53.0 10.8 0.04 13.6 0.1 9.9 7 2 2 9 9 9 4 TPR repeat TPR_10 PF13374.6 EKX35281.1 - 2e-09 37.0 15.1 0.00011 22.0 0.0 8.5 11 0 0 11 11 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX35281.1 - 3.4e-09 36.7 0.0 0.22 11.7 0.0 6.4 5 2 2 7 7 7 3 Tetratricopeptide repeat SNAP PF14938.6 EKX35281.1 - 1e-07 31.7 8.3 0.0019 17.7 0.1 5.4 5 0 0 5 5 5 1 Soluble NSF attachment protein, SNAP ANAPC3 PF12895.7 EKX35281.1 - 9.5e-07 29.0 25.8 0.034 14.4 0.0 8.2 7 3 1 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 Tcf25 PF04910.14 EKX35281.1 - 0.0002 20.6 1.9 0.7 8.9 0.0 4.4 4 1 1 5 5 5 2 Transcriptional repressor TCF25 DUF2989 PF11207.8 EKX35281.1 - 0.00064 19.5 0.5 0.00064 19.5 0.5 3.9 4 0 0 4 4 4 1 Protein of unknown function (DUF2989) DUF627 PF04781.12 EKX35281.1 - 0.0014 18.6 4.7 5.9 6.9 0.1 5.2 4 2 1 5 5 5 0 Protein of unknown function (DUF627) RPN7 PF10602.9 EKX35281.1 - 0.0034 17.1 7.9 0.52 10.0 1.0 4.1 3 1 0 3 3 3 1 26S proteasome subunit RPN7 DUF2225 PF09986.9 EKX35281.1 - 0.0048 16.7 14.9 0.19 11.5 0.7 5.2 3 1 1 5 5 5 2 Uncharacterized protein conserved in bacteria (DUF2225) HrpB1_HrpK PF09613.10 EKX35281.1 - 0.0075 15.9 0.1 0.81 9.3 0.0 3.0 3 0 0 3 3 2 1 Bacterial type III secretion protein (HrpB1_HrpK) Coatomer_E PF04733.14 EKX35281.1 - 0.015 14.7 1.3 0.12 11.7 0.3 3.1 3 2 0 4 4 3 0 Coatomer epsilon subunit TPPII_N PF12583.8 EKX35281.1 - 0.015 15.8 0.3 0.18 12.4 0.0 2.8 3 0 0 3 3 3 0 Tripeptidyl peptidase II N terminal Fis1_TPR_C PF14853.6 EKX35281.1 - 0.027 14.5 8.0 1.4 9.1 0.0 5.5 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat FAT PF02259.23 EKX35281.1 - 0.057 12.6 7.6 0.15 11.2 2.0 3.8 3 2 1 4 4 4 0 FAT domain PPR PF01535.20 EKX35281.1 - 0.084 13.2 2.0 1.4e+02 3.1 0.0 4.8 5 0 0 5 5 3 0 PPR repeat TPR_15 PF13429.6 EKX35281.1 - 0.084 12.1 15.4 1 8.5 0.4 6.2 3 2 3 7 7 6 0 Tetratricopeptide repeat TOM20_plant PF06552.12 EKX35281.1 - 0.091 12.5 3.6 0.82 9.4 0.1 3.9 4 1 2 6 6 6 0 Plant specific mitochondrial import receptor subunit TOM20 Clathrin PF00637.20 EKX35281.1 - 0.21 11.4 17.4 0.076 12.9 0.8 4.7 4 2 0 4 4 4 0 Region in Clathrin and VPS DUF4810 PF16068.5 EKX35281.1 - 0.59 10.7 2.7 9.9 6.8 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4810) Sel1 PF08238.12 EKX35281.1 - 1.1 10.1 11.8 97 3.9 0.1 6.3 8 0 0 8 8 5 0 Sel1 repeat Ubiq-assoc PF09145.10 EKX35281.1 - 1.4 9.0 3.6 11 6.2 0.0 3.6 3 0 0 3 3 2 0 Ubiquitin-associated G-patch PF01585.23 EKX35282.1 - 5e-13 48.7 1.3 1.4e-12 47.3 1.3 1.8 1 0 0 1 1 1 1 G-patch domain Cwf_Cwc_15 PF04889.12 EKX35283.1 - 0.18 11.5 15.1 0.42 10.3 15.1 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.13 EKX35283.1 - 0.27 11.2 7.9 0.42 10.5 7.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4637 PF15470.6 EKX35283.1 - 1 9.1 7.6 2.8 7.7 7.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) RXT2_N PF08595.11 EKX35283.1 - 2.5 8.1 8.9 5 7.1 8.9 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal SAPS PF04499.15 EKX35283.1 - 9.5 4.9 8.0 17 4.1 8.0 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FAM176 PF14851.6 EKX35283.1 - 9.7 5.8 8.8 21 4.7 8.8 1.6 1 0 0 1 1 1 0 FAM176 family Pox_Ag35 PF03286.14 EKX35283.1 - 10 5.9 10.1 24 4.6 10.1 1.7 1 1 0 1 1 1 0 Pox virus Ag35 surface protein DUF2408 PF10303.9 EKX35284.1 - 0.0078 16.8 8.9 0.0078 16.8 8.9 5.3 3 3 1 4 4 4 1 Protein of unknown function (DUF2408) Baculo_PEP_C PF04513.12 EKX35284.1 - 0.29 11.2 14.3 1.8 8.6 0.3 4.4 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Img2 PF05046.14 EKX35284.1 - 0.73 10.2 3.9 3 8.2 0.9 3.3 2 1 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) DUF2935 PF11155.8 EKX35284.1 - 0.79 10.1 8.8 5.5 7.3 5.3 3.9 2 2 0 2 2 2 0 Domain of unknown function (DUF2935) DUF1664 PF07889.12 EKX35284.1 - 4.9 7.2 46.4 1.2 9.2 3.6 6.6 2 2 5 7 7 7 0 Protein of unknown function (DUF1664) Glyco_transf_41 PF13844.6 EKX35285.1 - 1.8e-46 158.6 0.0 7.2e-25 87.4 0.0 2.3 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_2 PF07719.17 EKX35285.1 - 1.2e-05 25.0 2.1 0.48 10.7 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX35285.1 - 4.9e-05 23.0 3.5 1.6 8.7 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX35285.1 - 0.0038 17.3 3.1 17 5.9 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX35285.1 - 0.0064 16.3 3.0 5 7.1 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX35285.1 - 0.023 15.0 4.7 4.1 7.8 0.2 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX35285.1 - 0.23 12.4 0.8 76 4.5 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_C2 PF00648.21 EKX35286.1 - 9.3e-67 225.1 0.0 3.1e-66 223.4 0.0 1.8 2 0 0 2 2 2 1 Calpain family cysteine protease zf-GRF PF06839.12 EKX35286.1 - 3.1e-12 46.4 3.6 7.2e-12 45.2 3.6 1.7 1 0 0 1 1 1 1 GRF zinc finger RHH_6 PF16762.5 EKX35286.1 - 1.5 9.5 4.7 5.8 7.6 4.7 2.0 1 0 0 1 1 1 0 Ribbon-helix-helix domain Aldedh PF00171.22 EKX35287.1 - 3.6e-55 187.3 0.0 5e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ANAPC4_WD40 PF12894.7 EKX35287.1 - 1.6e-07 31.6 0.0 4.5e-06 26.9 0.0 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EKX35287.1 - 3.4e-06 27.7 2.2 3.8 8.5 0.0 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat EST1_DNA_bind PF10373.9 EKX35288.1 - 1.1e-34 120.3 1.2 8.8e-33 114.0 1.2 2.3 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 EKX35288.1 - 1.6e-19 70.9 1.1 2.6e-19 70.2 0.1 1.9 2 0 0 2 2 2 1 Telomerase activating protein Est1 TPR_20 PF14561.6 EKX35288.1 - 0.012 15.9 0.2 0.52 10.7 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat FNIP_C PF14638.6 EKX35288.1 - 0.075 12.7 0.2 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus Myc_N PF01056.18 EKX35288.1 - 7.5 6.3 10.3 0.65 9.8 4.9 1.9 2 0 0 2 2 2 0 Myc amino-terminal region RPT PF13446.6 EKX35289.1 - 0.093 12.7 0.0 0.41 10.6 0.0 2.0 2 1 0 2 2 2 0 A repeated domain in UCH-protein Alpha_adaptin_C PF02296.16 EKX35289.1 - 0.85 9.8 14.3 13 6.1 0.8 5.0 2 1 3 5 5 5 0 Alpha adaptin AP2, C-terminal domain Pkinase PF00069.25 EKX35290.1 - 5.9e-44 150.4 0.0 6.6e-44 150.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX35290.1 - 1.4e-36 126.1 0.0 1.6e-36 125.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX35290.1 - 8.9e-06 25.2 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EKX35290.1 - 0.0036 17.3 0.0 0.0075 16.2 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX35290.1 - 0.0038 16.6 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EKX35290.1 - 0.025 14.2 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DUF5635 PF18685.1 EKX35290.1 - 0.097 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5635) Big_9 PF17963.1 EKX35291.1 - 7.8 7.3 25.1 0.54 11.0 0.3 6.6 7 1 0 7 7 7 0 Bacterial Ig domain CGI-121 PF08617.10 EKX35292.1 - 1.5e-20 73.9 0.2 1.8e-20 73.7 0.2 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 LRR_4 PF12799.7 EKX35294.1 - 1.5e-26 92.0 19.6 3.3e-07 30.5 0.1 4.9 4 1 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX35294.1 - 2.5e-21 75.2 22.7 1e-08 34.8 3.0 4.9 3 1 2 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 EKX35294.1 - 2.9e-11 43.2 7.6 1.1e-05 25.1 2.8 2.6 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 EKX35294.1 - 1.5e-06 27.9 16.9 1.2 10.0 0.0 7.6 7 1 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.6 EKX35294.1 - 3.5e-06 26.6 27.5 0.54 10.5 0.1 8.1 7 1 1 8 8 8 5 Leucine Rich repeat LRR_2 PF07723.13 EKX35294.1 - 0.0058 17.2 5.8 1.5 9.6 0.3 4.9 6 0 0 6 6 6 1 Leucine Rich Repeat FKBP_C PF00254.28 EKX35295.1 - 3.7e-32 110.5 0.1 8.5e-32 109.4 0.1 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase BTHB PF18410.1 EKX35295.1 - 5.7e-14 51.7 1.7 7.7e-14 51.3 0.3 1.9 2 0 0 2 2 2 1 Basic tilted helix bundle domain DUF3221 PF11518.8 EKX35295.1 - 0.025 14.9 2.8 0.1 12.9 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3221) LsmAD PF06741.13 EKX35295.1 - 0.14 12.8 3.9 0.29 11.7 3.9 1.5 1 0 0 1 1 1 0 LsmAD domain FancD2 PF14631.6 EKX35295.1 - 0.2 9.0 3.9 0.24 8.8 3.9 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Atg14 PF10186.9 EKX35296.1 - 5.2 6.1 20.4 0.48 9.5 7.1 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Myb_DNA-bind_7 PF15963.5 EKX35297.1 - 2.6e-18 65.7 1.2 2.6e-18 65.7 1.2 2.2 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EKX35297.1 - 0.00014 21.9 0.2 0.00056 20.0 0.1 2.2 1 1 1 2 2 2 1 Myb-like DNA-binding domain PIEZO PF15917.5 EKX35297.1 - 0.25 10.8 6.1 0.91 9.0 6.1 1.9 1 0 0 1 1 1 0 Piezo Bac_export_2 PF01312.19 EKX35297.1 - 7.2 5.7 5.3 11 5.1 5.3 1.2 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family LETM1 PF07766.13 EKX35298.1 - 0.11 11.9 2.0 0.5 9.7 0.1 2.0 1 1 1 2 2 2 0 LETM1-like protein LCM PF04072.14 EKX35299.1 - 5.3e-29 101.5 0.0 8.6e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Ribosomal_L23eN PF03939.13 EKX35301.1 - 1.8e-17 63.3 16.7 3.6e-17 62.3 16.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 EKX35301.1 - 5.3e-13 49.1 2.3 5.3e-13 49.1 2.3 2.8 2 2 0 2 2 2 1 Ribosomal protein L23 TusA PF01206.17 EKX35301.1 - 0.1 12.4 0.3 0.19 11.6 0.0 1.6 2 0 0 2 2 2 0 Sulfurtransferase TusA FUSC_2 PF13515.6 EKX35302.1 - 4.9e-12 46.1 26.0 3e-06 27.4 15.5 2.4 2 0 0 2 2 2 2 Fusaric acid resistance protein-like DUF4295 PF14128.6 EKX35302.1 - 0.17 11.7 0.1 0.37 10.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4295) ALMT PF11744.8 EKX35302.1 - 1.9 7.2 9.4 0.47 9.2 5.9 1.7 2 0 0 2 2 2 0 Aluminium activated malate transporter NTF2 PF02136.20 EKX35303.1 - 7.3e-34 116.9 0.0 8.2e-34 116.7 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 EKX35303.1 - 0.021 14.8 0.0 0.024 14.6 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 DUF4440 PF14534.6 EKX35303.1 - 0.024 15.0 0.0 0.031 14.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) MOZ_SAS PF01853.18 EKX35304.1 - 2e-85 284.9 0.8 5e-85 283.7 0.0 1.8 2 0 0 2 2 2 1 MOZ/SAS family zf-MYST PF17772.1 EKX35304.1 - 1.1e-25 88.9 4.9 1.1e-25 88.9 4.9 2.2 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 EKX35304.1 - 1.1e-10 41.3 0.9 3.5e-10 39.6 0.9 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 EKX35304.1 - 0.019 15.4 0.0 0.038 14.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain IF2_N PF04760.15 EKX35304.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region DnaJ_C PF01556.18 EKX35305.1 - 2.6e-43 147.6 1.1 3.9e-43 147.1 1.1 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EKX35305.1 - 5.2e-23 81.0 0.8 8.9e-23 80.2 0.8 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EKX35305.1 - 4.8e-16 58.9 16.1 9.1e-16 58.0 16.1 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EKX35305.1 - 3.9e-06 26.7 11.0 0.0015 18.5 1.3 2.6 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EKX35305.1 - 0.022 14.8 8.0 1.3 9.1 0.4 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_10 PF16685.5 EKX35305.1 - 4.7 7.4 7.2 9.2 6.5 4.3 2.3 1 1 1 2 2 2 0 zinc RING finger of MSL2 zinc-ribbons_6 PF07191.12 EKX35305.1 - 7.9 6.5 9.9 39 4.3 9.9 2.1 1 1 0 1 1 1 0 zinc-ribbons Stk19 PF10494.9 EKX35306.1 - 2.9e-26 92.7 0.9 1.7e-25 90.2 0.9 2.2 1 1 0 1 1 1 1 Serine-threonine protein kinase 19 PH PF00169.29 EKX35307.1 - 0.031 14.8 0.1 0.11 13.1 0.1 1.9 1 0 0 1 1 1 0 PH domain Tim17 PF02466.19 EKX35308.1 - 1.2e-18 67.4 11.3 1.2e-18 67.4 11.3 1.8 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family WD40 PF00400.32 EKX35309.1 - 2.2e-43 145.4 24.2 2.4e-07 31.3 0.0 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX35309.1 - 5.3e-12 45.9 1.0 0.00058 20.1 0.1 4.6 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EKX35309.1 - 0.0011 18.4 0.0 0.083 12.2 0.0 3.0 2 1 1 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 EKX35309.1 - 0.0015 17.6 1.4 0.22 10.4 0.0 3.3 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EKX35309.1 - 0.0036 17.2 0.2 0.88 9.4 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EKX35309.1 - 0.023 13.4 0.2 0.41 9.2 0.0 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Frtz PF11768.8 EKX35309.1 - 0.17 10.2 0.2 1.1 7.5 0.0 2.2 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz SDA1 PF05285.12 EKX35309.1 - 0.27 10.6 20.1 0.35 10.2 20.1 1.1 1 0 0 1 1 1 0 SDA1 Mcl1_mid PF12341.8 EKX35310.1 - 1.6e-82 277.2 1.0 7.3e-82 275.0 0.3 2.2 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 EKX35310.1 - 3.2e-25 87.9 5.0 2.3e-07 31.4 0.0 7.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX35310.1 - 4.2e-14 52.6 0.3 3.4e-05 24.0 0.0 5.2 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX35310.1 - 0.0002 20.4 0.1 2.5 7.0 0.0 3.6 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 EKX35310.1 - 0.0083 15.2 0.1 0.23 10.5 0.1 2.2 1 1 1 2 2 2 1 Coatomer WD associated region Nucleoporin_N PF08801.11 EKX35310.1 - 0.028 13.2 0.4 1.6 7.4 0.0 2.7 3 0 0 3 3 3 0 Nup133 N terminal like Hira PF07569.11 EKX35310.1 - 0.053 13.2 0.0 9.1 5.9 0.0 3.1 3 0 0 3 3 3 0 TUP1-like enhancer of split IKI3 PF04762.12 EKX35310.1 - 0.13 10.2 0.0 2.3 6.1 0.0 2.1 1 1 1 2 2 2 0 IKI3 family Tachylectin PF14517.6 EKX35310.1 - 0.17 11.4 0.0 0.39 10.2 0.0 1.5 1 0 0 1 1 1 0 Tachylectin PD40 PF07676.12 EKX35310.1 - 0.59 10.1 2.2 7.2 6.7 0.1 3.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF5392 PF17370.2 EKX35311.1 - 0.15 12.2 1.1 0.36 10.9 0.0 2.0 1 1 0 2 2 2 0 Family of unknown function (DUF5392) Pkinase PF00069.25 EKX35312.1 - 0.00068 19.1 0.0 0.00068 19.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Apolipoprotein PF01442.18 EKX35313.1 - 7e-16 58.7 24.7 2.6e-13 50.3 18.5 2.9 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 EKX35313.1 - 2.4e-10 40.6 9.3 0.00052 20.1 8.0 3.8 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus TolA_bind_tri PF16331.5 EKX35313.1 - 1.8e-08 34.3 24.6 0.063 13.4 1.5 5.4 2 1 2 4 4 4 3 TolA binding protein trimerisation Phasin PF05597.11 EKX35313.1 - 6.5e-07 29.4 22.9 0.0011 19.0 5.6 4.2 1 1 2 4 4 4 3 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF3584 PF12128.8 EKX35313.1 - 1.3e-05 23.0 16.2 1.9e-05 22.5 16.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) HR1 PF02185.16 EKX35313.1 - 1.7e-05 24.8 23.9 0.23 11.6 0.2 5.8 2 1 2 4 4 3 2 Hr1 repeat DUF1351 PF07083.11 EKX35313.1 - 2.9e-05 23.9 5.2 0.019 14.8 0.5 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF1351) DUF3502 PF12010.8 EKX35313.1 - 4.1e-05 24.2 2.5 1.3 9.7 0.1 3.5 1 1 2 3 3 3 1 Domain of unknown function (DUF3502) Prominin PF05478.11 EKX35313.1 - 6e-05 21.2 13.9 6e-05 21.2 13.9 1.8 1 1 1 2 2 2 2 Prominin CdvA PF18822.1 EKX35313.1 - 8e-05 22.5 28.0 0.033 14.0 3.0 5.3 2 1 4 6 6 6 1 CdvA-like coiled-coil domain Img2 PF05046.14 EKX35313.1 - 9.5e-05 22.6 7.5 0.015 15.6 0.0 4.2 1 1 2 3 3 3 1 Mitochondrial large subunit ribosomal protein (Img2) TPR_MLP1_2 PF07926.12 EKX35313.1 - 0.00015 21.8 27.3 0.051 13.6 3.6 4.7 2 1 2 4 4 4 2 TPR/MLP1/MLP2-like protein DUF4795 PF16043.5 EKX35313.1 - 0.00016 21.3 31.2 0.12 12.0 7.0 3.5 1 1 2 3 3 3 2 Domain of unknown function (DUF4795) DUF1640 PF07798.11 EKX35313.1 - 0.00024 21.2 31.8 0.02 15.0 7.3 3.7 2 1 2 4 4 3 2 Protein of unknown function (DUF1640) DUF5082 PF16888.5 EKX35313.1 - 0.00028 21.1 18.3 0.03 14.6 3.2 3.4 2 1 2 4 4 3 2 Domain of unknown function (DUF5082) ApoLp-III PF07464.11 EKX35313.1 - 0.00049 20.2 18.6 0.03 14.4 1.9 2.9 1 1 2 3 3 3 2 Apolipophorin-III precursor (apoLp-III) Phage_Mu_Gam PF07352.12 EKX35313.1 - 0.00055 19.9 9.6 0.25 11.2 0.5 3.6 2 1 2 4 4 3 1 Bacteriophage Mu Gam like protein DUF1664 PF07889.12 EKX35313.1 - 0.00056 20.0 25.2 0.19 11.8 6.9 3.9 1 1 2 3 3 3 1 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 EKX35313.1 - 0.00062 20.0 23.9 0.02 15.1 10.2 3.9 1 1 2 4 4 4 3 Fibrinogen alpha/beta chain family Cortex-I_coil PF09304.10 EKX35313.1 - 0.00064 19.9 22.6 2.6 8.3 0.8 5.0 1 1 2 3 3 3 0 Cortexillin I, coiled coil MtrG PF04210.13 EKX35313.1 - 0.00068 19.4 10.7 21 5.1 0.1 6.2 1 1 9 10 10 9 0 Tetrahydromethanopterin S-methyltransferase, subunit G SKA2 PF16740.5 EKX35313.1 - 0.00078 19.2 17.4 0.05 13.4 1.6 4.0 2 1 1 3 3 3 1 Spindle and kinetochore-associated protein 2 Muted PF14942.6 EKX35313.1 - 0.00085 19.7 26.0 0.0022 18.4 12.7 3.4 1 1 2 3 3 3 1 Organelle biogenesis, Muted-like protein TSC22 PF01166.18 EKX35313.1 - 0.00086 19.6 10.6 4.6 7.6 0.2 4.7 5 0 0 5 5 4 0 TSC-22/dip/bun family DUF4618 PF15397.6 EKX35313.1 - 0.001 18.6 29.8 0.27 10.6 9.3 3.8 1 1 3 4 4 4 2 Domain of unknown function (DUF4618) DUF4164 PF13747.6 EKX35313.1 - 0.001 19.3 19.4 0.022 15.0 6.4 3.7 2 1 3 5 5 4 1 Domain of unknown function (DUF4164) DUF2730 PF10805.8 EKX35313.1 - 0.0014 18.7 27.2 1.8 8.7 2.1 5.6 1 1 3 4 4 4 0 Protein of unknown function (DUF2730) DUF4407 PF14362.6 EKX35313.1 - 0.0016 17.9 6.0 0.25 10.7 0.5 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4407) Phage_TAC_11 PF11836.8 EKX35313.1 - 0.0023 18.0 0.6 26 5.0 0.1 4.6 1 1 3 4 4 4 0 Phage tail tube protein, GTA-gp10 Nsp1_C PF05064.13 EKX35313.1 - 0.0024 17.7 20.3 0.67 9.8 1.4 4.4 1 1 3 4 4 4 3 Nsp1-like C-terminal region Filament PF00038.21 EKX35313.1 - 0.0027 17.3 26.0 0.22 11.1 13.5 3.3 1 1 1 3 3 3 2 Intermediate filament protein Remorin_C PF03763.13 EKX35313.1 - 0.0032 17.3 18.7 0.039 13.8 2.4 3.8 2 1 2 4 4 3 2 Remorin, C-terminal region Rbsn PF11464.8 EKX35313.1 - 0.0037 16.9 8.5 6.5 6.6 0.1 4.6 4 0 0 4 4 3 0 Rabenosyn Rab binding domain FapA PF03961.13 EKX35313.1 - 0.004 15.8 18.6 0.13 10.8 4.8 2.3 1 1 1 2 2 2 2 Flagellar Assembly Protein A DUF5053 PF16476.5 EKX35313.1 - 0.0052 16.4 1.8 6 6.6 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF5053) Nup54 PF13874.6 EKX35313.1 - 0.0053 16.9 15.8 0.06 13.4 5.8 2.5 1 1 1 2 2 2 1 Nucleoporin complex subunit 54 ApoO PF09769.9 EKX35313.1 - 0.0053 16.7 5.0 1.1 9.2 0.1 3.7 1 1 2 3 3 3 1 Apolipoprotein O EspB_PE PF18625.1 EKX35313.1 - 0.0058 17.1 0.2 15 6.1 0.0 3.5 2 1 1 3 3 3 0 ESX-1 secreted protein B PE domain Allexi_40kDa PF05549.11 EKX35313.1 - 0.0071 15.9 18.6 0.13 11.7 7.0 3.1 1 1 3 4 4 4 2 Allexivirus 40kDa protein Syntaxin PF00804.25 EKX35313.1 - 0.0087 15.7 20.5 0.035 13.8 3.2 3.4 2 1 1 3 3 3 1 Syntaxin COG2 PF06148.11 EKX35313.1 - 0.0093 16.1 24.2 0.34 11.0 2.5 4.8 1 1 3 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 ARGLU PF15346.6 EKX35313.1 - 0.0097 15.8 24.4 0.031 14.1 4.4 3.3 1 1 2 3 3 3 1 Arginine and glutamate-rich 1 DUF713 PF05218.14 EKX35313.1 - 0.01 15.6 10.0 0.051 13.3 1.6 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF713) LXG PF04740.12 EKX35313.1 - 0.011 15.5 23.3 0.14 11.9 12.4 3.6 1 1 3 4 4 4 0 LXG domain of WXG superfamily Vps54_N PF10475.9 EKX35313.1 - 0.012 14.9 16.9 1.3 8.3 1.1 4.3 1 1 3 4 4 4 0 Vacuolar-sorting protein 54, of GARP complex Leu_zip PF15294.6 EKX35313.1 - 0.012 15.1 29.0 0.034 13.7 17.4 2.8 1 1 2 3 3 3 0 Leucine zipper Tup_N PF08581.10 EKX35313.1 - 0.014 15.7 24.0 2 8.8 1.1 5.6 2 1 4 6 6 6 0 Tup N-terminal FliJ PF02050.16 EKX35313.1 - 0.014 15.6 9.5 1.8 8.8 0.9 3.7 1 1 1 3 3 3 0 Flagellar FliJ protein K-box PF01486.17 EKX35313.1 - 0.015 15.4 33.1 0.15 12.2 0.6 5.9 1 1 5 6 6 6 0 K-box region APG6_N PF17675.1 EKX35313.1 - 0.016 15.7 22.0 0.73 10.4 11.6 3.0 1 1 2 3 3 3 0 Apg6 coiled-coil region Spc7 PF08317.11 EKX35313.1 - 0.016 14.1 26.9 0.054 12.4 17.5 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein FlaC_arch PF05377.11 EKX35313.1 - 0.02 15.3 36.5 0.51 10.8 0.6 6.9 2 1 2 4 4 2 0 Flagella accessory protein C (FlaC) DUF4226 PF10774.9 EKX35313.1 - 0.021 15.1 3.5 12 6.3 0.1 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4226) Sds3 PF08598.11 EKX35313.1 - 0.022 14.7 18.5 1.6 8.7 12.8 3.4 1 1 1 2 2 2 0 Sds3-like CLZ PF16526.5 EKX35313.1 - 0.028 14.8 32.3 4.6 7.7 1.3 5.9 2 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3135 PF11333.8 EKX35313.1 - 0.028 14.6 4.4 6.7 7.0 0.1 4.1 2 1 3 5 5 3 0 Protein of unknown function (DUF3135) HalX PF08663.10 EKX35313.1 - 0.03 14.6 17.5 0.14 12.5 1.3 4.6 1 1 3 4 4 4 0 HalX domain REF PF05755.12 EKX35313.1 - 0.032 14.0 1.4 0.24 11.2 0.4 2.2 1 1 0 2 2 2 0 Rubber elongation factor protein (REF) Rootletin PF15035.6 EKX35313.1 - 0.035 14.1 26.3 2.1 8.4 0.1 4.2 2 1 3 5 5 4 0 Ciliary rootlet component, centrosome cohesion Hemagglutinin PF00509.18 EKX35313.1 - 0.035 12.5 12.7 0.12 10.8 0.7 3.3 1 1 3 4 4 4 0 Haemagglutinin SF-assemblin PF06705.11 EKX35313.1 - 0.038 13.3 18.0 0.4 10.0 15.4 2.5 1 1 1 2 2 2 0 SF-assemblin/beta giardin FAM184 PF15665.5 EKX35313.1 - 0.04 13.7 27.5 0.032 14.0 5.2 3.0 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B YojJ PF10372.9 EKX35313.1 - 0.04 14.0 21.9 4.9 7.3 0.7 5.5 2 1 3 5 5 5 0 Bacterial membrane-spanning protein N-terminus Exonuc_VII_L PF02601.15 EKX35313.1 - 0.044 13.3 17.4 1.5 8.3 17.2 2.2 1 1 0 1 1 1 0 Exonuclease VII, large subunit AAA_13 PF13166.6 EKX35313.1 - 0.048 12.3 14.2 0.16 10.5 14.0 1.8 1 1 0 1 1 1 0 AAA domain PIN_8 PF18476.1 EKX35313.1 - 0.049 13.5 14.8 1.1 9.1 6.8 2.9 1 1 2 3 3 3 0 PIN like domain CHDCT2 PF08074.11 EKX35313.1 - 0.049 13.8 14.2 4.2 7.5 5.1 4.0 1 1 3 4 4 4 0 CHDCT2 (NUC038) domain Bacillus_HBL PF05791.11 EKX35313.1 - 0.054 13.3 14.4 0.16 11.8 2.0 3.2 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) ING PF12998.7 EKX35313.1 - 0.055 14.1 14.5 3.2 8.4 0.2 3.7 1 1 2 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding GTP-bdg_M PF16360.5 EKX35313.1 - 0.085 13.5 12.4 4.1 8.1 2.5 3.9 1 1 3 4 4 4 0 GTP-binding GTPase Middle Region Nbl1_Borealin_N PF10444.9 EKX35313.1 - 0.088 12.5 18.6 5.8 6.6 0.2 5.9 2 1 6 8 8 7 0 Nbl1 / Borealin N terminal SHE3 PF17078.5 EKX35313.1 - 0.089 12.5 22.2 0.49 10.1 11.8 3.0 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 Gp58 PF07902.11 EKX35313.1 - 0.098 10.9 11.8 0.13 10.5 10.5 1.6 1 1 1 2 2 2 0 gp58-like protein Uso1_p115_C PF04871.13 EKX35313.1 - 0.1 12.9 30.1 2e+03 -0.9 0.1 3.6 1 1 1 2 2 0 0 Uso1 / p115 like vesicle tethering protein, C terminal region YgaB PF14182.6 EKX35313.1 - 0.12 12.8 20.0 2.4 8.6 3.1 5.0 2 1 3 5 5 5 0 YgaB-like protein LidA_Long_CC PF18641.1 EKX35313.1 - 0.12 12.4 20.1 1.1 9.3 1.8 4.6 2 1 3 5 5 4 0 LidA long coiled-coil domain Seryl_tRNA_N PF02403.22 EKX35313.1 - 0.13 12.5 21.9 2.4 8.4 4.7 4.1 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Mst1_SARAH PF11629.8 EKX35313.1 - 0.15 12.2 26.4 2.8 8.1 0.3 7.0 2 1 6 8 8 7 0 C terminal SARAH domain of Mst1 DUF677 PF05055.12 EKX35313.1 - 0.15 10.9 23.3 0.038 12.9 3.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF677) YlqD PF11068.8 EKX35313.1 - 0.16 12.3 22.5 0.76 10.1 2.5 3.8 1 1 3 4 4 4 0 YlqD protein JHBP PF06585.11 EKX35313.1 - 0.17 11.0 0.8 10 5.2 0.1 3.1 1 1 2 4 4 3 0 Haemolymph juvenile hormone binding protein (JHBP) AIP3 PF03915.13 EKX35313.1 - 0.18 10.9 23.7 9.9 5.1 13.0 2.6 1 1 1 2 2 2 0 Actin interacting protein 3 LMBR1 PF04791.16 EKX35313.1 - 0.2 10.5 13.2 0.77 8.6 1.9 2.0 1 1 1 2 2 2 0 LMBR1-like membrane protein pP_pnuc_1 PF18165.1 EKX35313.1 - 0.22 11.4 5.1 14 5.5 0.2 3.7 3 1 1 4 4 4 0 Predicted pPIWI-associating nuclease Mt_ATP-synt_D PF05873.12 EKX35313.1 - 0.22 11.3 13.1 0.97 9.3 0.1 4.0 1 1 2 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) HSBP1 PF06825.12 EKX35313.1 - 0.26 11.2 29.2 0.42 10.5 0.8 5.9 2 1 3 5 5 3 0 Heat shock factor binding protein 1 DUF2408 PF10303.9 EKX35313.1 - 0.34 11.5 21.4 7.7 7.1 0.4 4.0 1 1 1 2 2 1 0 Protein of unknown function (DUF2408) TMPIT PF07851.13 EKX35313.1 - 0.39 9.9 21.7 5.1 6.3 10.8 2.7 1 1 2 3 3 3 0 TMPIT-like protein BAR_3 PF16746.5 EKX35313.1 - 0.43 10.2 21.6 0.17 11.6 12.3 2.4 1 1 2 3 3 3 0 BAR domain of APPL family ORF11CD3 PF10549.9 EKX35313.1 - 0.46 10.6 3.5 65 3.7 0.1 3.8 3 0 0 3 3 3 0 ORF11CD3 domain DUF883 PF05957.13 EKX35313.1 - 0.61 10.7 17.8 6.8 7.4 2.2 4.3 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF883) DUF4845 PF16137.5 EKX35313.1 - 0.62 11.0 3.3 2.4 9.1 0.0 3.4 1 1 2 3 3 1 0 Domain of unknown function (DUF4845) DUF2802 PF10975.8 EKX35313.1 - 0.7 10.1 22.0 4.4 7.5 0.3 6.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2802) Cnn_1N PF07989.11 EKX35313.1 - 0.78 9.9 22.4 0.049 13.8 3.4 3.8 1 1 2 3 3 2 0 Centrosomin N-terminal motif 1 AcylCoA_dehyd_C PF12186.8 EKX35313.1 - 1 9.5 11.7 11 6.2 0.1 4.6 2 1 3 5 5 5 0 Acyl-CoA dehydrogenase C terminal DUF1690 PF07956.11 EKX35313.1 - 1 9.7 27.0 7 7.1 12.7 3.6 1 1 1 3 3 3 0 Protein of Unknown function (DUF1690) FAM76 PF16046.5 EKX35313.1 - 1.1 8.6 23.1 1.1 8.5 2.7 3.0 1 1 1 2 2 2 0 FAM76 protein TRPM_tetra PF16519.5 EKX35313.1 - 1.2 9.2 31.1 1 9.5 1.8 6.1 2 1 4 6 6 6 0 Tetramerisation domain of TRPM DUF4455 PF14643.6 EKX35313.1 - 1.4 7.5 24.2 0.2 10.3 18.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4455) BshC PF10079.9 EKX35313.1 - 1.4 7.6 18.7 0.33 9.6 5.6 2.8 1 1 1 3 3 3 0 Bacillithiol biosynthesis BshC BMFP PF04380.13 EKX35313.1 - 1.5 9.4 18.0 65 4.1 0.2 6.0 2 1 2 4 4 4 0 Membrane fusogenic activity DUF148 PF02520.17 EKX35313.1 - 1.5 8.9 15.9 14 5.8 0.5 3.9 2 1 1 3 3 2 0 Domain of unknown function DUF148 T3SS_needle_F PF09392.10 EKX35313.1 - 1.7 8.9 16.0 51 4.2 0.6 6.1 1 1 2 3 3 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Connexin50 PF03509.14 EKX35313.1 - 1.7 9.5 13.0 33 5.4 0.2 4.9 2 1 2 4 4 3 0 Gap junction alpha-8 protein (Cx50) Cauli_DNA-bind PF03310.13 EKX35313.1 - 2 8.5 12.6 19 5.4 0.4 3.9 1 1 4 5 5 4 0 Caulimovirus DNA-binding protein Syntaxin-6_N PF09177.11 EKX35313.1 - 2.1 9.0 19.4 1.6e+03 -0.3 0.0 3.6 1 1 1 2 2 0 0 Syntaxin 6, N-terminal Fzo_mitofusin PF04799.13 EKX35313.1 - 2.1 7.9 24.7 2.4 7.7 6.4 4.0 2 1 2 4 4 4 0 fzo-like conserved region Lectin_N PF03954.14 EKX35313.1 - 2.2 8.0 21.7 0.46 10.2 3.5 2.9 2 1 1 3 3 2 0 Hepatic lectin, N-terminal domain DUF4709 PF15821.5 EKX35313.1 - 2.3 8.5 17.0 11 6.3 3.1 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4709) RICH PF05062.12 EKX35313.1 - 2.5 8.5 21.6 4.1 7.8 6.5 4.3 2 1 1 3 3 1 0 RICH domain ACCA PF03255.14 EKX35313.1 - 2.5 8.0 19.5 13 5.7 2.7 4.0 1 1 3 4 4 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit PKcGMP_CC PF16808.5 EKX35313.1 - 2.9 7.8 13.0 15 5.6 0.1 5.6 3 3 2 5 5 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase MnmE_helical PF12631.7 EKX35313.1 - 2.9 8.0 14.9 7.4 6.7 9.5 2.4 1 1 1 2 2 2 0 MnmE helical domain DUF2203 PF09969.9 EKX35313.1 - 3 8.6 17.2 7.6e+02 0.8 0.1 3.8 1 1 1 2 2 1 0 Uncharacterized conserved protein (DUF2203) Ax_dynein_light PF10211.9 EKX35313.1 - 3.2 7.7 23.5 0.2 11.6 3.0 3.0 2 1 2 4 4 3 0 Axonemal dynein light chain Snapin_Pallidin PF14712.6 EKX35313.1 - 3.3 8.2 22.1 3.9 8.0 2.8 4.4 2 1 2 4 4 4 0 Snapin/Pallidin ZYG-11_interact PF05884.12 EKX35313.1 - 3.6 6.9 10.9 43 3.4 0.1 3.0 1 1 1 2 2 2 0 Interactor of ZYG-11 Peptidase_M2 PF01401.18 EKX35313.1 - 4.2 5.9 9.8 6.2 5.3 8.8 1.7 1 1 1 2 2 2 0 Angiotensin-converting enzyme DUF948 PF06103.11 EKX35313.1 - 4.4 7.6 19.0 16 5.9 1.4 4.8 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF948) Noelin-1 PF12308.8 EKX35313.1 - 4.8 7.2 18.8 5.5 7.0 0.8 4.6 1 1 3 4 4 4 0 Neurogenesis glycoprotein Tmemb_cc2 PF10267.9 EKX35313.1 - 5.3 6.1 25.5 2.7 7.0 8.9 2.6 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein BST2 PF16716.5 EKX35313.1 - 5.3 7.7 24.4 16 6.1 4.1 4.6 2 1 3 5 5 4 0 Bone marrow stromal antigen 2 TMEM210 PF15195.6 EKX35313.1 - 5.9 7.4 7.4 27 5.2 0.3 3.2 1 1 2 3 3 2 0 TMEM210 family Ribosomal_S7e PF01251.18 EKX35313.1 - 6.3 6.5 15.7 15 5.3 1.2 4.3 1 1 3 4 4 4 0 Ribosomal protein S7e DUF745 PF05335.13 EKX35313.1 - 7.5 6.2 11.3 5.5 6.7 1.1 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF745) Baculo_p24 PF05073.12 EKX35313.1 - 7.6 6.3 12.8 20 4.9 0.8 2.8 1 1 1 2 2 2 0 Baculovirus P24 capsid protein KIP1 PF07765.12 EKX35313.1 - 8.2 6.6 26.7 9.5 6.4 1.5 5.8 2 1 4 6 6 5 0 KIP1-like protein DUF4140 PF13600.6 EKX35313.1 - 8.2 6.9 10.9 42 4.7 3.1 4.0 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) STAT_alpha PF01017.20 EKX35313.1 - 8.4 6.3 21.9 8.7 6.2 3.2 3.7 1 1 1 2 2 2 0 STAT protein, all-alpha domain PLAC9 PF15205.6 EKX35313.1 - 8.7 6.8 9.1 28 5.2 0.2 3.7 1 1 1 3 3 3 0 Placenta-specific protein 9 LPP PF04728.13 EKX35313.1 - 9.4 6.7 16.5 37 4.8 0.2 5.4 2 1 3 5 5 5 0 Lipoprotein leucine-zipper DUF2089 PF09862.9 EKX35313.1 - 9.7 6.3 12.5 57 3.8 0.5 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2089) Tweety PF04906.13 EKX35313.1 - 9.8 4.7 16.7 11 4.5 2.2 3.0 1 1 2 3 3 3 0 Tweety Fucokinase PF07959.12 EKX35314.1 - 1.3e-10 40.9 0.0 1.4e-06 27.6 0.0 2.2 2 0 0 2 2 2 2 L-fucokinase GHMP_kinases_N PF00288.26 EKX35314.1 - 8.9e-08 32.3 0.1 3.5e-07 30.3 0.1 2.1 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EKX35314.1 - 0.022 15.1 0.1 0.08 13.3 0.1 2.1 1 0 0 1 1 1 0 GHMP kinases C terminal NR_Repeat PF14046.6 EKX35314.1 - 0.061 13.5 0.9 0.16 12.1 0.9 1.7 1 0 0 1 1 1 0 Nuclear receptor repeat DUF737 PF05300.11 EKX35315.1 - 0.00039 20.8 7.2 0.00039 20.8 7.2 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF737) zf-AN1 PF01428.16 EKX35317.1 - 5.9e-10 39.1 9.9 1e-09 38.4 9.9 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger DUF4732 PF15876.5 EKX35317.1 - 0.057 13.5 0.2 0.088 12.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4732) Transp_Tc5_C PF04236.15 EKX35317.1 - 0.15 12.5 4.7 0.19 12.1 3.2 2.0 1 1 1 2 2 2 0 Tc5 transposase C-terminal domain PRNT PF15174.6 EKX35317.1 - 0.17 12.0 2.6 0.19 11.8 1.1 1.9 2 0 0 2 2 2 0 Prion-related protein testis-specific Peptidase_M3 PF01432.20 EKX35318.1 - 2.2e-54 185.5 3.0 5.7e-42 144.5 0.1 2.4 1 1 1 2 2 2 2 Peptidase family M3 Peptidase_M50B PF13398.6 EKX35318.1 - 0.0065 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase M50B-like TPR_17 PF13431.6 EKX35319.1 - 3.4e-20 70.9 4.4 0.00078 19.7 0.1 5.4 4 1 1 5 5 5 4 Tetratricopeptide repeat EF-hand_6 PF13405.6 EKX35319.1 - 3.7e-19 67.0 3.6 0.00017 21.2 0.0 5.2 4 1 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 EKX35319.1 - 1.5e-18 64.9 3.7 6.5e-06 25.3 0.1 5.0 5 0 0 5 5 4 3 EF hand EF-hand_7 PF13499.6 EKX35319.1 - 8.4e-17 61.4 1.4 9.5e-07 29.2 0.1 4.0 3 2 1 4 4 3 3 EF-hand domain pair TPR_1 PF00515.28 EKX35319.1 - 1.1e-12 47.2 3.1 0.0046 16.7 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX35319.1 - 1.2e-12 47.3 4.8 0.035 13.8 0.1 5.2 5 0 0 5 5 5 4 TPR repeat EF-hand_5 PF13202.6 EKX35319.1 - 3.1e-12 45.4 7.9 4.4e-05 22.8 0.1 4.9 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 EKX35319.1 - 1e-10 41.3 0.4 0.00067 19.5 0.0 4.0 5 0 0 5 5 4 2 EF-hand domain pair TPR_2 PF07719.17 EKX35319.1 - 1.1e-10 40.8 1.2 0.049 13.8 0.1 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX35319.1 - 2.3e-09 37.3 1.1 0.1 13.5 0.0 4.8 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX35319.1 - 3.1e-09 37.0 2.6 0.0017 18.6 0.1 3.4 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX35319.1 - 8.1e-09 35.0 0.0 0.049 13.9 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX35319.1 - 5.5e-07 30.0 0.9 0.66 10.5 0.0 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX35319.1 - 6.5e-07 28.9 2.1 0.11 12.6 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX35319.1 - 0.00065 20.3 0.1 0.39 11.4 0.0 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat Coatomer_E PF04733.14 EKX35319.1 - 0.001 18.5 0.2 0.6 9.5 0.0 3.0 1 1 2 3 3 3 1 Coatomer epsilon subunit TPR_10 PF13374.6 EKX35319.1 - 0.0015 18.3 0.2 1.4 8.8 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat SPARC_Ca_bdg PF10591.9 EKX35319.1 - 0.0068 16.7 0.0 15 5.9 0.0 4.2 4 0 0 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 EKX35319.1 - 0.012 15.7 0.0 9.8 6.5 0.0 2.7 2 0 0 2 2 2 0 Dockerin type I domain DUF5112 PF17139.4 EKX35319.1 - 0.12 11.9 0.0 0.29 10.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5112) TPPII_N PF12583.8 EKX35319.1 - 0.34 11.5 5.0 7.7 7.1 0.0 3.3 3 1 1 4 4 3 0 Tripeptidyl peptidase II N terminal TPR_9 PF13371.6 EKX35319.1 - 0.65 10.2 5.1 16 5.7 0.2 3.6 3 1 0 3 3 2 0 Tetratricopeptide repeat Keratin_2_head PF16208.5 EKX35319.1 - 3.6 7.7 23.5 8.1 6.6 23.5 1.5 1 0 0 1 1 1 0 Keratin type II head RRM_1 PF00076.22 EKX35321.1 - 3.2e-13 49.3 0.0 5.5e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) efThoc1 PF11957.8 EKX35321.1 - 0.039 12.6 0.1 0.045 12.4 0.1 1.1 1 0 0 1 1 1 0 THO complex subunit 1 transcription elongation factor Arm-DNA-bind_4 PF14657.6 EKX35321.1 - 0.28 11.0 1.2 0.53 10.1 1.2 1.4 1 0 0 1 1 1 0 Arm DNA-binding domain Thioredoxin PF00085.20 EKX35324.1 - 6.9e-39 132.0 0.4 7.7e-27 93.3 0.0 4.0 3 1 2 5 5 5 2 Thioredoxin Thioredoxin_6 PF13848.6 EKX35324.1 - 1.2e-29 103.6 1.0 3.6e-23 82.4 2.0 3.2 1 1 1 3 3 3 3 Thioredoxin-like domain Calsequestrin PF01216.17 EKX35324.1 - 1.8e-08 33.8 0.0 3.5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_2 PF13098.6 EKX35324.1 - 3.4e-07 30.7 0.0 3.3e-05 24.3 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EKX35324.1 - 7.3e-07 29.3 0.0 9.9e-06 25.7 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_8 PF13905.6 EKX35324.1 - 1.4e-06 28.5 0.0 0.00032 21.0 0.0 3.2 2 1 1 3 3 3 2 Thioredoxin-like Redoxin PF08534.10 EKX35324.1 - 0.0016 18.2 0.3 0.53 10.0 0.0 3.1 3 0 0 3 3 3 1 Redoxin HyaE PF07449.11 EKX35324.1 - 0.0088 16.0 0.0 0.069 13.1 0.0 2.5 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 EKX35324.1 - 0.028 14.4 0.0 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 AhpC/TSA family TraF PF13728.6 EKX35324.1 - 0.11 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 F plasmid transfer operon protein Glutaredoxin PF00462.24 EKX35324.1 - 0.12 12.6 0.1 1 9.6 0.1 2.4 2 1 0 2 2 2 0 Glutaredoxin MORN PF02493.20 EKX35325.1 - 1.7e-28 96.8 56.8 0.00046 19.9 1.0 8.1 8 0 0 8 8 8 8 MORN repeat Sec62 PF03839.16 EKX35326.1 - 0.00062 19.3 0.1 0.00083 18.9 0.1 1.1 1 0 0 1 1 1 1 Translocation protein Sec62 zf-CDGSH PF09360.10 EKX35327.1 - 4.9e-18 65.1 5.4 3.7e-11 43.1 0.5 2.2 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type DUF4571 PF15137.6 EKX35327.1 - 0.11 12.2 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4571) Endonuclease_1 PF04231.13 EKX35331.1 - 1.1e-37 130.0 0.1 1.8e-27 96.5 0.1 2.2 2 0 0 2 2 2 2 Endonuclease I CSD PF00313.22 EKX35331.1 - 3.7e-11 42.7 0.1 6.8e-11 41.9 0.1 1.5 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain DUF3382 PF11862.8 EKX35332.1 - 0.037 14.3 0.3 0.04 14.2 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) MORN PF02493.20 EKX35334.1 - 5.5e-10 38.5 11.3 0.0033 17.2 0.1 3.5 3 0 0 3 3 3 3 MORN repeat Coleoptericin PF06286.11 EKX35337.1 - 0.085 13.0 8.2 25 5.0 0.2 3.8 1 1 4 5 5 5 0 Coleoptericin DUF2651 PF10852.8 EKX35337.1 - 0.15 12.7 3.2 9.3 6.9 0.4 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2651) RWP-RK PF02042.15 EKX35339.1 - 4.4e-16 58.6 0.0 7.4e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_6 PF01418.17 EKX35339.1 - 0.016 15.2 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family TAP42 PF04177.12 EKX35340.1 - 1.3e-53 182.3 6.8 1.5e-53 182.0 6.8 1.1 1 0 0 1 1 1 1 TAP42-like family RWP-RK PF02042.15 EKX35341.1 - 5.7e-16 58.2 0.1 4.1e-15 55.5 0.0 2.1 2 0 0 2 2 2 1 RWP-RK domain HTH_6 PF01418.17 EKX35341.1 - 0.041 13.9 0.0 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family MFS_1 PF07690.16 EKX35342.1 - 3e-28 98.8 35.6 3.4e-28 98.6 35.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 EKX35342.1 - 9.3e-24 83.6 17.9 3e-11 42.3 0.3 4.0 2 1 2 4 4 4 4 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 EKX35342.1 - 6.5e-07 28.6 4.9 6.5e-07 28.6 4.9 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter FtsX PF02687.21 EKX35342.1 - 0.065 13.7 0.6 0.065 13.7 0.6 4.2 3 1 0 3 3 3 0 FtsX-like permease family DnaJ PF00226.31 EKX35344.1 - 5.8e-21 74.4 0.1 7.8e-21 74.0 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 EKX35344.1 - 0.054 13.4 0.1 0.2 11.6 0.1 1.9 1 1 1 2 2 2 0 A repeated domain in UCH-protein RWP-RK PF02042.15 EKX35346.1 - 1.3e-14 53.9 0.0 2.3e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain Ank_5 PF13857.6 EKX35349.1 - 5.4e-08 33.0 0.0 1.1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX35349.1 - 9.8e-08 32.4 0.1 3.9e-06 27.3 0.0 2.8 2 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX35349.1 - 5.7e-07 30.0 0.0 2e-06 28.3 0.0 2.0 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX35349.1 - 3.2e-06 27.0 0.0 2.2e-05 24.5 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EKX35349.1 - 0.0011 19.3 0.0 0.0064 16.9 0.0 2.3 3 0 0 3 3 3 1 Ankyrin repeat PTEN_C2 PF10409.9 EKX35350.1 - 4.4e-08 33.0 0.2 1.5e-07 31.3 0.0 2.0 2 1 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein Ion_trans PF00520.31 EKX35351.1 - 5.1e-107 356.6 55.9 1.1e-40 139.5 18.7 4.5 4 1 0 4 4 4 4 Ion transport protein MerR-DNA-bind PF09278.11 EKX35351.1 - 1.3 9.7 3.9 1.3 9.6 0.2 2.4 2 0 0 2 2 2 0 MerR, DNA binding DUF2357 PF09823.9 EKX35352.1 - 0.033 13.5 2.6 0.52 9.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2357) FlxA PF14282.6 EKX35352.1 - 0.047 13.7 0.2 0.047 13.7 0.2 3.1 3 0 0 3 3 3 0 FlxA-like protein ZapB PF06005.12 EKX35352.1 - 0.069 13.6 1.8 0.069 13.6 1.8 2.9 3 0 0 3 3 3 0 Cell division protein ZapB betaPIX_CC PF16523.5 EKX35352.1 - 0.098 12.5 4.0 0.1 12.4 0.5 2.4 2 0 0 2 2 2 0 betaPIX coiled coil OmpH PF03938.14 EKX35352.1 - 0.47 10.8 6.7 2.3 8.5 0.5 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) HSCB_C PF07743.13 EKX35352.1 - 0.97 10.0 6.9 0.64 10.6 0.2 2.7 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain DivIC PF04977.15 EKX35352.1 - 4 7.3 10.1 5.7 6.8 1.9 3.1 3 0 0 3 3 3 0 Septum formation initiator BST2 PF16716.5 EKX35352.1 - 4.1 8.1 7.3 4.4 8.0 0.0 2.8 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 BRE1 PF08647.11 EKX35352.1 - 6.8 6.8 11.1 18 5.5 0.6 3.2 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase Seryl_tRNA_N PF02403.22 EKX35352.1 - 8.2 6.7 9.4 6.1 7.1 0.7 3.0 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Pkinase PF00069.25 EKX35353.1 - 3.3e-21 75.8 0.0 4.3e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX35353.1 - 7.9e-20 71.2 0.0 1.5e-19 70.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Gal11_ABD1 PF18535.1 EKX35353.1 - 0.23 11.6 0.9 2.1 8.5 0.5 2.2 2 0 0 2 2 2 0 Gal11 activator-binding domain (ABD1) Efg1 PF10153.9 EKX35354.1 - 1.2e-31 109.4 18.4 1.2e-31 109.4 18.4 2.6 2 1 0 2 2 2 1 rRNA-processing protein Efg1 Oxidored_nitro PF00148.19 EKX35354.1 - 0.05 12.3 1.0 0.058 12.1 1.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Ank_3 PF13606.6 EKX35355.1 - 5.1e-07 29.5 0.3 0.0073 16.7 0.1 4.2 4 0 0 4 4 4 1 Ankyrin repeat Ank_2 PF12796.7 EKX35355.1 - 1.7e-06 28.5 0.0 1.1e-05 26.0 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX35355.1 - 2e-05 25.0 0.1 0.059 14.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX35355.1 - 6.6e-05 23.1 0.5 0.0022 18.2 0.2 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX35355.1 - 0.00067 20.0 0.2 0.041 14.3 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeat PQQ_3 PF13570.6 EKX35356.1 - 5e-27 93.6 22.7 1.8e-05 25.1 0.1 9.0 9 1 0 9 9 9 7 PQQ-like domain PQQ_2 PF13360.6 EKX35356.1 - 3.1e-23 82.6 1.9 1.4e-13 51.0 0.3 3.1 2 1 1 3 3 3 2 PQQ-like domain PQQ PF01011.21 EKX35356.1 - 1.3e-15 56.5 15.2 0.03 14.3 0.1 7.5 8 0 0 8 8 8 6 PQQ enzyme repeat HA PF03457.14 EKX35357.1 - 1.7e-18 66.7 0.8 9e-18 64.4 0.8 2.4 1 0 0 1 1 1 1 Helicase associated domain PDZ_2 PF13180.6 EKX35357.1 - 2.9e-05 24.3 0.0 6.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX35357.1 - 0.025 14.5 0.2 0.078 13.0 0.0 1.9 2 0 0 2 2 2 0 Tricorn protease PDZ domain Peptidase_A22B PF04258.13 EKX35359.1 - 3.5e-25 89.1 0.2 4.8e-25 88.7 0.2 1.2 1 0 0 1 1 1 1 Signal peptide peptidase Gelsolin PF00626.22 EKX35362.1 - 7.9e-33 112.2 0.0 1.7e-10 40.7 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat SAC3_GANP PF03399.16 EKX35363.1 - 5.5e-28 98.2 3.7 1.3e-25 90.4 3.7 2.0 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EKX35363.1 - 6.6e-10 39.1 0.0 1.1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family CHDCT2 PF08074.11 EKX35363.1 - 0.016 15.4 0.1 0.023 14.9 0.1 1.2 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain GnsAB_toxin PF08178.11 EKX35366.1 - 0.039 13.9 0.1 0.37 10.7 0.0 2.4 2 0 0 2 2 2 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system AMP-binding_C_2 PF14535.6 EKX35366.1 - 0.37 11.1 5.3 1.9 8.8 0.8 2.7 1 1 2 3 3 3 0 AMP-binding enzyme C-terminal domain DUF641 PF04859.12 EKX35366.1 - 2.6 8.4 15.2 7.7 6.9 2.8 2.6 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Csm1_N PF18504.1 EKX35366.1 - 7.8 6.9 14.3 7 7.1 3.6 3.3 2 1 1 3 3 3 0 Csm1 N-terminal domain WD40 PF00400.32 EKX35369.1 - 2.8e-14 53.3 0.2 0.56 11.2 0.0 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX35369.1 - 2.9e-07 30.7 0.0 0.00084 19.6 0.0 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EKX35369.1 - 0.19 11.0 0.0 2.3 7.5 0.0 2.4 2 1 1 3 3 3 0 WD40-like domain Aminotran_5 PF00266.19 EKX35370.1 - 1.8e-38 132.5 0.0 2.2e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_3 PF00202.21 EKX35370.1 - 0.12 10.9 0.1 0.26 9.9 0.1 1.6 1 1 0 1 1 1 0 Aminotransferase class-III DegT_DnrJ_EryC1 PF01041.17 EKX35370.1 - 0.16 11.2 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family PDZ_6 PF17820.1 EKX35371.1 - 1.2e-07 31.5 0.0 3.8e-07 29.8 0.0 2.0 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX35371.1 - 0.0019 18.5 0.1 0.0059 16.9 0.1 1.8 1 0 0 1 1 1 1 PDZ domain Bacillus_HBL PF05791.11 EKX35371.1 - 0.0042 16.9 4.1 0.0042 16.9 4.1 4.3 2 1 2 4 4 4 2 Bacillus haemolytic enterotoxin (HBL) BORCS7 PF16088.5 EKX35371.1 - 0.0057 16.9 5.5 0.0057 16.9 5.5 3.8 3 1 1 4 4 4 1 BLOC-1-related complex sub-unit 7 DUF1664 PF07889.12 EKX35371.1 - 2.1 8.4 43.3 0.25 11.4 6.6 4.8 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) WD40 PF00400.32 EKX35373.1 - 1.8e-12 47.5 6.3 1.8e-07 31.7 0.7 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_3 PF13570.6 EKX35373.1 - 0.057 13.9 0.0 4.6 7.9 0.0 2.6 2 0 0 2 2 2 0 PQQ-like domain zf-RVT PF13966.6 EKX35374.1 - 0.0012 19.6 0.3 0.061 14.0 0.3 2.9 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Ank_4 PF13637.6 EKX35376.1 - 1.8e-08 34.7 0.0 6.1e-08 33.1 0.0 1.9 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX35376.1 - 6e-07 30.0 0.0 1.2e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX35376.1 - 7e-06 26.0 0.0 0.0029 18.0 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EKX35376.1 - 0.00041 20.6 0.1 0.004 17.4 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) PTCB-BRCT PF12738.7 EKX35377.1 - 4.8e-13 48.9 0.2 1.1e-10 41.3 0.1 2.5 2 0 0 2 2 2 2 twin BRCT domain BRCT PF00533.26 EKX35377.1 - 2.8e-10 40.4 0.2 1e-07 32.2 0.0 2.7 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EKX35377.1 - 4.6e-07 30.2 0.3 0.006 17.0 0.1 2.9 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EKX35377.1 - 0.16 12.2 0.1 1.8 8.9 0.0 2.7 3 0 0 3 3 3 0 DNA ligase 3 BRCT domain NAC PF01849.18 EKX35380.1 - 4.8e-23 80.9 0.1 8.3e-23 80.1 0.1 1.4 1 0 0 1 1 1 1 NAC domain vATP-synt_E PF01991.18 EKX35382.1 - 2.9e-58 196.6 2.5 3.3e-58 196.4 2.5 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit RWP-RK PF02042.15 EKX35385.1 - 3.1e-13 49.5 0.0 3e-12 46.3 0.0 2.1 2 0 0 2 2 2 1 RWP-RK domain HTH_8 PF02954.19 EKX35385.1 - 0.041 13.7 0.3 0.14 12.0 0.2 1.9 1 1 0 1 1 1 0 Bacterial regulatory protein, Fis family HTH_24 PF13412.6 EKX35385.1 - 0.25 10.9 1.2 2.1 8.0 0.1 2.5 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Ank_4 PF13637.6 EKX35386.1 - 2.5e-14 53.4 0.1 8.2e-08 32.7 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX35386.1 - 7.5e-13 48.9 0.0 1.7e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX35386.1 - 4.6e-10 38.9 0.0 0.005 17.2 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EKX35386.1 - 2.7e-08 33.9 0.0 0.0026 18.1 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EKX35386.1 - 1.1e-06 28.8 0.0 0.0048 17.2 0.0 2.8 1 1 0 2 2 2 2 Ankyrin repeats (many copies) G0-G1_switch_2 PF15103.6 EKX35386.1 - 0.048 14.1 0.1 0.048 14.1 0.1 2.1 2 0 0 2 2 2 0 G0/G1 switch protein 2 Nop14 PF04147.12 EKX35386.1 - 1.7 6.8 60.4 2 6.6 48.8 2.1 2 0 0 2 2 2 0 Nop14-like family CPSF100_C PF13299.6 EKX35386.1 - 3.4 7.8 14.1 1.2 9.3 0.5 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Mpp10 PF04006.12 EKX35386.1 - 3.4 6.0 54.0 2.3 6.5 5.6 2.1 2 0 0 2 2 2 0 Mpp10 protein NT5C PF06941.12 EKX35387.1 - 2.5e-20 73.1 0.0 3.1e-20 72.8 0.0 1.0 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) PLDc_2 PF13091.6 EKX35387.1 - 0.039 13.8 0.0 0.098 12.5 0.0 1.8 1 1 0 1 1 1 0 PLD-like domain Hydrolase PF00702.26 EKX35387.1 - 0.065 13.5 0.0 0.082 13.2 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EKX35387.1 - 0.13 12.4 0.0 0.76 9.9 0.0 2.0 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Glycos_transf_1 PF00534.20 EKX35388.1 - 1.1e-22 80.4 0.0 1.2e-22 80.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EKX35388.1 - 1.6e-18 67.4 0.7 2.1e-18 67.0 0.7 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EKX35388.1 - 1e-14 54.7 0.0 1.3e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 PDZ_6 PF17820.1 EKX35389.1 - 7.5e-11 41.7 0.0 1.3e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX35389.1 - 4e-09 36.7 0.0 6e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX35389.1 - 0.00068 19.9 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX35389.1 - 0.015 15.2 0.0 0.044 13.8 0.0 1.9 2 1 0 2 2 2 0 Tricorn protease PDZ domain GRASP55_65 PF04495.14 EKX35389.1 - 0.016 15.5 0.0 0.019 15.3 0.0 1.2 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain DUF1181 PF06680.11 EKX35390.1 - 0.056 13.3 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1181) Peptidase_S49_N PF08496.10 EKX35390.1 - 2.7 8.0 12.2 0.53 10.3 8.2 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF745 PF05335.13 EKX35391.1 - 0.04 13.6 8.8 0.065 13.0 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Sec34 PF04136.15 EKX35391.1 - 0.055 13.3 3.4 0.11 12.3 3.4 1.6 1 0 0 1 1 1 0 Sec34-like family YlqD PF11068.8 EKX35391.1 - 0.066 13.6 6.4 0.11 12.8 6.4 1.3 1 0 0 1 1 1 0 YlqD protein RWP-RK PF02042.15 EKX35392.1 - 8.5e-15 54.5 0.1 1.7e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX35392.1 - 0.077 12.8 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Abhydrolase_6 PF12697.7 EKX35396.1 - 2e-06 28.6 2.4 0.00014 22.5 0.2 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EKX35396.1 - 2.9e-06 27.1 0.1 0.0043 16.7 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EKX35396.1 - 0.00085 18.8 0.1 0.011 15.3 0.1 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EKX35396.1 - 0.0011 18.3 0.4 0.24 10.6 0.1 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EKX35396.1 - 0.065 12.8 0.6 0.65 9.5 0.0 2.0 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Asp2 PF16929.5 EKX35396.1 - 0.07 12.1 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter RPS31 PF17067.5 EKX35400.1 - 2.6e-05 24.3 0.1 3.2e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S31e Thx PF17070.5 EKX35400.1 - 0.59 10.3 5.1 1.2 9.4 5.1 1.5 1 0 0 1 1 1 0 30S ribosomal protein Thx Zn_ribbon_SprT PF17283.2 EKX35401.1 - 0.086 12.8 1.6 0.27 11.2 0.4 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Tmemb_9 PF05434.11 EKX35403.1 - 0.066 13.1 2.8 0.13 12.2 2.8 1.6 1 1 0 1 1 1 0 TMEM9 UPF0492 PF15744.5 EKX35403.1 - 0.07 12.3 6.6 0.086 12.0 6.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 STI1 PF17830.1 EKX35404.1 - 2.2e-13 49.9 9.0 5.9e-13 48.5 8.0 2.3 3 0 0 3 3 3 1 STI1 domain TPR_1 PF00515.28 EKX35404.1 - 5.1e-11 41.9 5.0 2.4e-06 27.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat HipN PF18253.1 EKX35404.1 - 6.2e-11 41.8 0.0 1.7e-10 40.4 0.0 1.8 1 0 0 1 1 1 1 Hsp70-interacting protein N N-terminal domain TPR_2 PF07719.17 EKX35404.1 - 1.7e-10 40.2 3.3 0.0028 17.6 0.1 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX35404.1 - 9.7e-08 32.5 3.9 0.0002 21.9 2.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX35404.1 - 4.3e-06 26.8 1.7 0.0011 19.0 0.3 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX35404.1 - 4e-05 23.7 0.3 0.0028 17.9 0.2 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX35404.1 - 0.00023 21.6 4.8 0.01 16.3 2.3 3.3 3 1 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX35404.1 - 0.00025 21.2 0.2 0.00046 20.3 0.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EKX35404.1 - 0.0011 19.2 1.6 0.012 15.9 0.4 3.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX35404.1 - 0.006 16.2 0.7 0.12 12.1 0.2 2.9 3 0 0 3 3 3 1 TPR repeat NYD-SP12_N PF15015.6 EKX35404.1 - 0.068 11.5 0.7 0.11 10.9 0.0 1.6 1 1 1 2 2 2 0 Spermatogenesis-associated, N-terminal TPR_8 PF13181.6 EKX35404.1 - 0.069 13.4 0.5 0.51 10.7 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX35404.1 - 0.2 12.6 2.4 14 6.8 0.2 3.9 2 1 2 4 4 4 0 Tetratricopeptide repeat Keratin_2_head PF16208.5 EKX35404.1 - 0.33 11.1 15.9 0.52 10.4 15.9 1.2 1 0 0 1 1 1 0 Keratin type II head Sporozoite_P67 PF05642.11 EKX35404.1 - 3.7 5.5 8.7 0.066 11.3 1.2 1.7 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Pap_E4 PF02711.14 EKX35405.1 - 0.015 16.2 0.0 0.023 15.7 0.0 1.2 1 0 0 1 1 1 0 E4 protein CPSase_L_D2 PF02786.17 EKX35407.1 - 8.8e-108 358.6 0.0 1.7e-81 272.8 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 EKX35407.1 - 1.5e-51 173.6 0.0 2.7e-51 172.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EKX35407.1 - 3e-47 160.9 0.0 7.1e-47 159.6 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 EKX35407.1 - 3.7e-38 130.6 0.0 8.6e-38 129.4 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 EKX35407.1 - 3.7e-21 75.5 0.0 1.6e-11 44.0 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EKX35407.1 - 4.1e-17 62.4 0.1 2.2e-07 30.6 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EKX35407.1 - 5.3e-13 48.8 0.0 4.1e-05 23.3 0.0 3.5 3 1 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 EKX35407.1 - 3.1e-08 33.8 0.1 0.00047 20.2 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.13 EKX35407.1 - 6.3e-06 26.1 0.7 0.00024 20.9 0.4 2.6 2 1 0 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.24 EKX35407.1 - 4.2e-05 23.4 0.0 0.0035 17.2 0.0 2.5 2 0 0 2 2 2 1 DJ-1/PfpI family GARS_A PF01071.19 EKX35407.1 - 0.00011 22.0 0.2 0.00051 19.9 0.0 2.2 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 EKX35407.1 - 0.0002 21.0 0.0 0.021 14.4 0.0 2.4 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 EKX35407.1 - 0.12 11.8 0.0 0.87 9.0 0.0 2.3 2 1 0 2 2 2 0 ATP-grasp domain LMF1 PF06762.14 EKX35408.1 - 1.5e-120 403.3 26.1 4.5e-67 227.1 14.0 2.7 2 1 1 3 3 3 2 Lipase maturation factor Mannosyl_trans4 PF15971.5 EKX35408.1 - 0.0061 16.4 0.8 0.019 14.8 0.8 1.8 1 0 0 1 1 1 1 DolP-mannose mannosyltransferase PA14 PF07691.12 EKX35409.1 - 0.00093 19.0 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 PA14 domain GLEYA PF10528.9 EKX35409.1 - 0.01 16.2 1.1 0.017 15.5 0.2 1.8 2 0 0 2 2 2 0 GLEYA domain PDZ_6 PF17820.1 EKX35410.1 - 3.7e-14 52.3 0.0 7.7e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX35410.1 - 8.9e-08 32.3 0.0 1.5e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX35410.1 - 3.3e-07 30.5 0.0 5.8e-07 29.8 0.0 1.4 1 1 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX35410.1 - 7.2e-06 25.9 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Tricorn protease PDZ domain RWP-RK PF02042.15 EKX35411.1 - 4e-13 49.1 0.2 6.3e-13 48.5 0.2 1.2 1 0 0 1 1 1 1 RWP-RK domain DnaJ_C PF01556.18 EKX35414.1 - 2.3e-35 121.9 0.0 3.3e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EKX35414.1 - 4.4e-27 94.0 2.5 7.6e-27 93.2 2.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EKX35414.1 - 4e-13 49.5 17.1 9.4e-13 48.3 17.1 1.7 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EKX35414.1 - 0.0075 16.2 20.5 0.14 12.1 7.2 3.3 1 1 2 3 3 3 2 Tryptophan RNA-binding attenuator protein inhibitory protein zf-RING_10 PF16685.5 EKX35414.1 - 1.3 9.2 5.1 0.37 11.0 0.3 2.2 1 1 1 2 2 2 0 zinc RING finger of MSL2 DSPn PF14671.6 EKX35415.1 - 1.7e-23 83.7 0.1 1.9e-22 80.2 0.1 2.0 1 1 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half Antifungal_prot PF11402.8 EKX35415.1 - 0.17 12.2 0.6 0.29 11.4 0.6 1.4 1 0 0 1 1 1 0 Antifungal protein CBS PF00571.28 EKX35416.1 - 4.1e-07 30.3 0.2 2.3e-06 27.9 0.0 2.1 2 1 0 2 2 2 1 CBS domain Voltage_CLC PF00654.20 EKX35417.1 - 1.1e-39 136.7 17.6 2e-33 116.1 9.9 3.5 2 1 1 3 3 3 2 Voltage gated chloride channel zf-MYND PF01753.18 EKX35418.1 - 2.5e-05 24.3 6.2 6.4e-05 23.0 6.2 1.7 1 0 0 1 1 1 1 MYND finger Zn_ribbon_17 PF17120.5 EKX35418.1 - 0.43 10.2 4.8 7.1 6.3 0.1 2.5 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type MRP-S34 PF16053.5 EKX35419.1 - 6.4e-09 35.5 0.1 9.5e-09 35.0 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 EF-hand_1 PF00036.32 EKX35420.1 - 3.2e-17 60.7 13.2 3.7e-08 32.4 0.8 4.3 4 1 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 EKX35420.1 - 1.3e-16 60.8 6.3 8.5e-09 35.8 0.9 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX35420.1 - 2.8e-15 54.9 11.7 1.1e-06 28.1 1.4 3.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EKX35420.1 - 3.1e-10 39.1 10.1 0.00013 21.3 0.5 3.9 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EKX35420.1 - 6.2e-09 35.6 5.8 5.7e-05 22.9 0.5 3.9 3 2 0 3 3 3 2 EF-hand domain pair ThiI PF02568.14 EKX35420.1 - 0.0064 16.1 0.2 3.6 7.1 0.1 2.1 2 0 0 2 2 2 2 Thiamine biosynthesis protein (ThiI) ZIP4_domain PF18292.1 EKX35420.1 - 0.008 16.1 0.1 0.22 11.4 0.1 2.1 1 1 1 2 2 2 1 Zinc transporter ZIP4 domain EF-hand_10 PF14788.6 EKX35420.1 - 0.016 15.0 5.9 0.53 10.2 0.2 3.4 2 1 1 3 3 3 0 EF hand DCX PF03607.17 EKX35420.1 - 0.021 14.9 0.0 9 6.5 0.0 2.3 2 0 0 2 2 2 0 Doublecortin Adenine_glyco PF03352.13 EKX35420.1 - 0.061 13.1 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyladenine glycosylase Caleosin PF05042.13 EKX35420.1 - 0.068 13.1 1.6 1 9.3 0.2 2.3 1 1 0 2 2 2 0 Caleosin related protein EF-hand_4 PF12763.7 EKX35420.1 - 0.077 12.9 4.6 3.4 7.7 1.3 2.9 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand T3SS_HrpK1 PF16937.5 EKX35420.1 - 0.097 12.3 2.8 1.5 8.5 1.7 2.2 1 1 0 1 1 1 0 Type III secretion system translocator protein, HrpF EF-hand_9 PF14658.6 EKX35420.1 - 0.16 12.3 1.9 18 5.7 0.1 2.5 2 1 1 3 3 3 0 EF-hand domain LETM1 PF07766.13 EKX35420.1 - 0.72 9.2 2.5 0.9 8.8 0.6 1.8 2 0 0 2 2 2 0 LETM1-like protein SPARC_Ca_bdg PF10591.9 EKX35420.1 - 1.1 9.7 4.3 4.4 7.7 0.5 2.4 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region S_100 PF01023.19 EKX35420.1 - 2.2 8.1 6.6 9.3 6.0 0.4 2.7 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain Aha1_N PF09229.11 EKX35421.1 - 1.9e-14 54.1 1.8 2.6e-14 53.6 1.8 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal BROMI PF14961.6 EKX35421.1 - 0.0024 15.4 0.0 0.003 15.1 0.0 1.1 1 0 0 1 1 1 1 Broad-minded protein PDZ_6 PF17820.1 EKX35425.1 - 1.2e-18 66.7 6.8 1.9e-09 37.2 3.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX35425.1 - 3.4e-14 52.9 3.1 2.5e-07 30.9 0.1 2.4 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 EKX35425.1 - 1e-12 48.2 7.1 4.5e-06 26.9 0.4 2.5 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 EKX35425.1 - 7.5e-06 25.8 1.3 0.0032 17.4 0.4 2.6 2 0 0 2 2 2 2 Tricorn protease PDZ domain Borrelia_P83 PF05262.11 EKX35425.1 - 0.0047 15.5 51.5 0.0071 14.9 51.5 1.3 1 0 0 1 1 1 1 Borrelia P83/100 protein CDC27 PF09507.10 EKX35425.1 - 0.022 14.2 60.3 0.028 13.8 60.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Caldesmon PF02029.15 EKX35425.1 - 0.052 12.3 60.0 0.077 11.8 60.0 1.2 1 0 0 1 1 1 0 Caldesmon THRAP3_BCLAF1 PF15440.6 EKX35425.1 - 0.51 9.3 42.1 0.63 9.0 42.1 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family DUF936 PF06075.12 EKX35425.1 - 1.2 8.0 30.9 1.4 7.7 30.9 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) SWI-SNF_Ssr4 PF08549.10 EKX35425.1 - 2 6.9 25.4 2.9 6.4 25.4 1.3 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) LRR_9 PF14580.6 EKX35426.1 - 1.3e-21 76.9 0.7 7.1e-19 68.0 0.2 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 EKX35426.1 - 1.1e-14 54.2 25.8 1e-05 25.7 0.5 4.2 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX35426.1 - 1.9e-10 40.4 4.9 1.2e-05 24.9 0.6 3.8 2 1 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 EKX35426.1 - 0.0019 18.1 2.4 11 6.4 0.2 4.8 5 0 0 5 5 5 1 Leucine Rich repeat Spc7_N PF15402.6 EKX35426.1 - 0.35 9.1 3.3 0.43 8.8 3.3 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 LRR_1 PF00560.33 EKX35426.1 - 7.8 7.5 9.4 3.6e+02 2.4 0.0 5.2 3 1 1 4 4 4 0 Leucine Rich Repeat Arm PF00514.23 EKX35427.1 - 7.2e-87 283.1 11.1 1.2e-11 44.2 0.0 9.3 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EKX35427.1 - 2e-33 114.3 0.0 5.4e-12 45.9 0.0 6.6 6 1 0 6 6 6 4 HEAT-like repeat HEAT PF02985.22 EKX35427.1 - 6.1e-23 78.9 0.6 4e-06 26.6 0.0 9.2 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.6 EKX35427.1 - 2.1e-22 79.3 0.0 2.5e-07 31.0 0.0 5.8 2 1 3 6 6 5 5 HEAT repeats Arm_3 PF16186.5 EKX35427.1 - 3.4e-21 74.5 0.1 3e-20 71.5 0.2 2.5 3 0 0 3 3 3 1 Atypical Arm repeat Cnd1 PF12717.7 EKX35427.1 - 2.9e-09 37.2 0.0 0.71 9.9 0.0 5.0 2 2 3 5 5 5 3 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 EKX35427.1 - 1.3e-07 31.7 0.0 0.01 16.0 0.0 4.2 5 0 0 5 5 5 2 V-ATPase subunit H IBB PF01749.20 EKX35427.1 - 4.7e-07 30.2 4.4 1.9e-06 28.2 3.4 2.5 3 0 0 3 3 3 1 Importin beta binding domain RICTOR_V PF14668.6 EKX35427.1 - 6.8e-07 29.4 0.5 0.64 10.3 0.0 4.8 5 2 0 5 5 5 2 Rapamycin-insensitive companion of mTOR, domain 5 Adaptin_N PF01602.20 EKX35427.1 - 4.6e-06 25.5 0.0 4.2 5.8 0.0 3.9 1 1 0 2 2 2 1 Adaptin N terminal region HEAT_PBS PF03130.16 EKX35427.1 - 1.4e-05 25.3 0.6 0.92 10.4 0.1 5.5 6 0 0 6 6 5 1 PBS lyase HEAT-like repeat Arm_2 PF04826.13 EKX35427.1 - 6.4e-05 22.5 0.2 0.18 11.2 0.0 3.7 2 1 2 4 4 4 1 Armadillo-like CTNNBL PF08216.11 EKX35427.1 - 0.0017 18.5 0.3 14 5.9 0.0 4.6 4 1 1 5 5 5 0 Catenin-beta-like, Arm-motif containing nuclear RasGEF_N_2 PF14663.6 EKX35427.1 - 0.0022 18.4 0.8 12 6.3 0.0 5.1 4 1 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Atx10homo_assoc PF09759.9 EKX35427.1 - 0.038 14.0 0.2 8.5 6.5 0.0 3.6 3 1 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain Mo25 PF08569.11 EKX35427.1 - 0.12 11.8 0.0 0.33 10.3 0.0 1.7 1 1 0 1 1 1 0 Mo25-like UPF0242 PF06785.11 EKX35429.1 - 0.0008 19.6 36.4 0.0016 18.6 13.6 2.9 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0242) N-terminus FPP PF05911.11 EKX35429.1 - 0.076 11.2 30.6 0.21 9.8 21.4 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Fez1 PF06818.15 EKX35429.1 - 0.24 11.8 35.8 0.022 15.2 15.1 3.2 1 1 2 3 3 3 0 Fez1 Syntaxin-6_N PF09177.11 EKX35429.1 - 0.3 11.7 26.1 19 5.9 2.1 4.7 1 1 3 4 4 4 0 Syntaxin 6, N-terminal DUF1910 PF08928.10 EKX35429.1 - 0.6 10.1 4.3 8.8 6.4 0.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1910) Fib_alpha PF08702.10 EKX35429.1 - 2.5 8.3 24.3 1.3 9.2 2.2 3.8 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family Sec8_exocyst PF04048.14 EKX35429.1 - 3.7 7.4 16.2 0.5 10.2 3.5 3.7 2 2 2 4 4 4 0 Sec8 exocyst complex component specific domain LPP PF04728.13 EKX35429.1 - 4.4 7.8 8.7 17 5.9 0.3 3.9 4 0 0 4 4 4 0 Lipoprotein leucine-zipper DUF745 PF05335.13 EKX35429.1 - 9.8 5.8 22.0 3.6 7.3 1.9 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF745) FAM25 PF15825.5 EKX35430.1 - 0.0022 18.3 0.2 0.0057 17.0 0.1 1.7 2 0 0 2 2 2 1 FAM25 family CitMHS PF03600.16 EKX35431.1 - 0.17 11.1 17.9 0.24 10.5 17.9 1.3 1 0 0 1 1 1 0 Citrate transporter DUF898 PF05987.13 EKX35431.1 - 2.2 7.3 22.2 4.4 6.3 22.2 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Sin3_corepress PF08295.12 EKX35432.1 - 8.2e-36 122.0 0.1 2.8e-35 120.3 0.1 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.21 EKX35432.1 - 2e-34 117.4 5.9 1.8e-17 63.2 0.4 3.7 3 0 0 3 3 3 2 Paired amphipathic helix repeat Ndc1_Nup PF09531.10 EKX35432.1 - 0.23 10.1 7.6 0.3 9.7 7.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup VIT1 PF01988.19 EKX35432.1 - 5.6 6.8 6.7 4.4 7.1 1.6 2.7 3 0 0 3 3 3 0 VIT family Presenilin PF01080.17 EKX35432.1 - 6.8 5.4 10.7 10 4.8 10.7 1.2 1 0 0 1 1 1 0 Presenilin MDFI PF15316.6 EKX35432.1 - 6.8 6.8 15.7 3.6 7.6 12.2 2.0 2 0 0 2 2 2 0 MyoD family inhibitor ALMT PF11744.8 EKX35432.1 - 7.9 5.2 8.5 11 4.7 8.5 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter MDM10 PF12519.8 EKX35433.1 - 0.023 13.6 5.1 0.04 12.8 5.1 1.4 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Usp PF00582.26 EKX35433.1 - 0.041 14.4 4.1 0.11 13.1 4.1 1.7 1 0 0 1 1 1 0 Universal stress protein family DUF4746 PF15928.5 EKX35433.1 - 0.075 12.4 9.6 0.14 11.5 9.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4065 PF13274.6 EKX35433.1 - 0.25 12.2 6.8 1 10.3 3.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) Zip PF02535.22 EKX35433.1 - 0.47 9.6 3.4 0.6 9.3 3.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Adaptin_binding PF10199.9 EKX35433.1 - 0.55 10.8 17.6 2.2 8.9 11.9 2.5 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Sec62 PF03839.16 EKX35433.1 - 0.69 9.4 7.5 1.3 8.4 7.5 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 NPR3 PF03666.13 EKX35433.1 - 0.74 8.5 10.9 1.5 7.5 10.9 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 NARP1 PF12569.8 EKX35433.1 - 1.9 7.3 14.9 3.4 6.5 14.9 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 MCM_bind PF09739.9 EKX35433.1 - 2.3 6.6 10.2 4.1 5.7 10.2 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Jak1_Phl PF17887.1 EKX35433.1 - 2.7 8.0 9.5 7.1 6.6 9.5 1.7 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain O-antigen_lig PF13425.6 EKX35433.1 - 3.1 6.5 6.8 5.2 5.7 6.8 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein RNA_pol_Rpc4 PF05132.14 EKX35433.1 - 3.5 8.1 12.1 8.4 6.8 12.1 1.7 1 0 0 1 1 1 0 RNA polymerase III RPC4 RRN3 PF05327.11 EKX35433.1 - 5.8 5.3 13.3 6 5.3 9.9 2.0 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 TRAP_alpha PF03896.16 EKX35433.1 - 8.3 5.5 10.6 16 4.6 10.6 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit EIIBC-GUT_N PF03612.14 EKX35433.1 - 9.6 5.9 9.2 24 4.6 9.2 1.7 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Myb_DNA-binding PF00249.31 EKX35434.1 - 1.4e-09 38.0 0.0 7.7e-09 35.6 0.0 1.9 1 1 0 1 1 1 1 Myb-like DNA-binding domain TEA PF01285.18 EKX35434.1 - 0.0055 16.8 0.1 0.011 15.8 0.1 1.5 1 1 0 1 1 1 1 TEA/ATTS domain Pam17 PF08566.10 EKX35434.1 - 0.078 12.8 0.0 0.089 12.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Arm PF00514.23 EKX35435.1 - 1.5e-25 88.3 3.9 0.0031 17.5 0.0 8.4 8 0 0 8 8 8 7 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EKX35435.1 - 2e-10 40.6 0.6 0.36 10.9 0.0 6.2 3 3 3 6 6 6 2 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 EKX35435.1 - 1.4e-07 31.8 11.5 0.16 12.5 0.1 6.0 6 0 0 6 6 6 3 HEAT-like repeat HEAT_2 PF13646.6 EKX35435.1 - 2.5e-05 24.6 13.0 0.72 10.3 0.3 4.4 3 1 0 3 3 3 3 HEAT repeats V-ATPase_H_N PF03224.14 EKX35435.1 - 0.00017 21.0 0.2 0.0017 17.7 0.2 2.2 1 1 0 1 1 1 1 V-ATPase subunit H Arm_2 PF04826.13 EKX35435.1 - 0.00065 19.2 1.1 1.1 8.7 0.2 3.1 3 0 0 3 3 3 2 Armadillo-like V-ATPase_H_C PF11698.8 EKX35435.1 - 0.0059 16.7 1.9 3.1 7.9 0.2 3.8 3 2 1 4 4 4 1 V-ATPase subunit H PUL PF08324.11 EKX35435.1 - 0.013 14.7 1.3 0.92 8.7 0.2 2.4 1 1 1 2 2 2 0 PUL domain Cnd3 PF12719.7 EKX35435.1 - 0.022 14.0 0.4 1.3 8.1 0.1 2.6 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain HATPase_c_4 PF13749.6 EKX35435.1 - 0.039 14.1 2.2 5.9 7.1 0.0 4.2 4 1 0 5 5 5 0 Putative ATP-dependent DNA helicase recG C-terminal HEAT PF02985.22 EKX35435.1 - 0.19 12.1 13.7 23 5.6 0.1 6.3 6 0 0 6 6 6 0 HEAT repeat CRS1_YhbY PF01985.21 EKX35435.1 - 0.62 10.3 6.1 9.4 6.5 0.1 4.5 4 1 1 5 5 5 0 CRS1 / YhbY (CRM) domain CHAT PF12770.7 EKX35436.1 - 0.0083 15.6 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 CHAT domain Peptidase_C13 PF01650.18 EKX35436.1 - 0.12 11.9 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Peptidase C13 family Glyco_transf_49 PF13896.6 EKX35437.1 - 2.6e-14 53.3 0.1 3.4e-05 23.4 0.1 3.1 2 1 0 2 2 2 2 Glycosyl-transferase for dystroglycan Cyclin_N PF00134.23 EKX35438.1 - 2.1e-06 27.5 0.2 4e-06 26.6 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain YukD PF08817.10 EKX35438.1 - 0.0072 17.0 0.0 0.019 15.6 0.0 1.7 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD G-patch PF01585.23 EKX35439.1 - 5.1e-10 39.1 1.7 8.6e-10 38.4 1.7 1.4 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 EKX35439.1 - 0.0028 17.4 0.0 0.006 16.4 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MatE PF01554.18 EKX35441.1 - 7.4e-19 68.0 4.7 7.4e-19 68.0 4.7 3.0 3 1 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 EKX35441.1 - 1.5e-08 34.8 8.0 1.5e-08 34.8 8.0 2.3 2 2 0 2 2 2 1 Polysaccharide biosynthesis C-terminal domain MurJ PF03023.14 EKX35441.1 - 5.9e-06 25.1 5.3 7.5e-06 24.8 5.3 1.3 1 1 0 1 1 1 1 Lipid II flippase MurJ Polysacc_synt PF01943.17 EKX35441.1 - 0.0033 16.9 9.7 0.068 12.5 1.3 3.3 2 1 0 3 3 3 2 Polysaccharide biosynthesis protein MoCF_biosynth PF00994.24 EKX35442.1 - 5.9e-28 97.3 0.0 1.2e-27 96.3 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain PAPS_reduct PF01507.19 EKX35442.1 - 9.6e-21 74.6 0.0 2.7e-18 66.6 0.0 2.3 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family PhoLip_ATPase_C PF16212.5 EKX35443.1 - 1.4e-58 198.6 11.4 1.4e-58 198.6 11.4 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EKX35443.1 - 1.4e-22 79.2 3.0 3.2e-22 78.0 3.0 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EKX35443.1 - 8e-10 39.4 3.6 4.3e-06 27.2 1.2 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EKX35443.1 - 2.5e-08 33.9 0.0 1.2e-07 31.8 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EKX35443.1 - 2.4e-05 23.9 0.1 0.00012 21.7 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase zf-ribbon_3 PF13248.6 EKX35443.1 - 0.13 11.7 0.9 0.26 10.8 0.9 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Hydrolase_3 PF08282.12 EKX35443.1 - 0.17 11.6 0.2 0.38 10.4 0.2 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase MENTAL PF10457.9 EKX35443.1 - 0.36 10.6 2.8 1 9.2 0.4 2.3 1 1 1 2 2 2 0 Cholesterol-capturing domain ZU5 PF00791.20 EKX35445.1 - 9.8e-06 25.8 0.0 2.1e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 ZU5 domain LapA_dom PF06305.11 EKX35445.1 - 0.14 12.0 1.8 0.15 11.9 0.3 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain SieB PF14163.6 EKX35445.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Super-infection exclusion protein B Pkinase PF00069.25 EKX35447.1 - 1.4e-53 182.0 0.1 3.7e-53 180.6 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX35447.1 - 6.7e-24 84.6 0.1 2.3e-23 82.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EKX35447.1 - 0.00013 22.0 0.0 0.00022 21.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EKX35447.1 - 0.02 14.5 0.1 0.041 13.5 0.1 1.5 1 1 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 EKX35447.1 - 0.025 14.2 0.3 0.041 13.4 0.3 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 EKX35447.1 - 0.079 12.3 0.1 0.19 11.1 0.1 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family IQ PF00612.27 EKX35448.1 - 0.00015 21.3 13.5 0.014 15.1 1.2 3.7 3 0 0 3 3 3 2 IQ calmodulin-binding motif Inositol_P PF00459.25 EKX35450.1 - 2.5e-70 237.1 0.1 3e-70 236.8 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family TPD52 PF04201.15 EKX35451.1 - 0.065 12.8 0.2 0.096 12.3 0.2 1.3 1 0 0 1 1 1 0 Tumour protein D52 family SAB PF04382.13 EKX35451.1 - 0.078 13.1 0.3 0.1 12.7 0.3 1.2 1 0 0 1 1 1 0 SAB domain PS-DH PF14765.6 EKX35451.1 - 0.12 11.6 0.3 0.13 11.5 0.3 1.0 1 0 0 1 1 1 0 Polyketide synthase dehydratase Beta_helix PF13229.6 EKX35452.1 - 4.1e-05 23.5 0.0 6.3e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Right handed beta helix region Pectate_lyase_3 PF12708.7 EKX35452.1 - 0.1 12.4 0.1 0.8 9.5 0.0 1.8 1 1 1 2 2 2 0 Pectate lyase superfamily protein Adeno_E1B_55K PF01696.17 EKX35452.1 - 0.13 10.9 3.2 0.19 10.4 3.2 1.2 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen Atx10homo_assoc PF09759.9 EKX35453.1 - 1.2e-17 63.8 13.0 1.5e-05 24.9 0.0 6.2 4 2 2 6 6 6 5 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 EKX35453.1 - 3e-16 58.8 15.7 0.0044 17.0 0.1 9.3 9 1 0 9 9 9 6 Armadillo/beta-catenin-like repeat DUF5578 PF17741.1 EKX35453.1 - 2.2e-07 30.6 4.8 0.0089 15.5 0.1 3.9 1 1 3 4 4 4 2 Family of unknown function (DUF5578) RYDR_ITPR PF01365.21 EKX35453.1 - 0.0066 15.9 6.2 0.29 10.5 1.5 3.4 3 1 0 3 3 3 2 RIH domain He_PIG PF05345.12 EKX35454.1 - 0.042 14.1 9.9 1 9.6 1.3 3.6 3 0 0 3 3 3 0 Putative Ig domain Na_Ca_ex PF01699.24 EKX35454.1 - 0.83 9.6 3.8 19 5.2 0.3 3.1 3 0 0 3 3 3 0 Sodium/calcium exchanger protein RWP-RK PF02042.15 EKX35455.1 - 8.9e-10 38.4 0.1 1.6e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_3 PF01381.22 EKX35455.1 - 0.031 14.4 0.1 0.1 12.7 0.1 1.9 1 1 1 2 2 2 0 Helix-turn-helix HTH_8 PF02954.19 EKX35455.1 - 0.12 12.2 0.1 0.26 11.1 0.1 1.6 1 1 0 1 1 1 0 Bacterial regulatory protein, Fis family RWP-RK PF02042.15 EKX35456.1 - 6.3e-05 22.9 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain HTH_37 PF13744.6 EKX35456.1 - 0.0094 15.9 0.2 0.017 15.1 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HMG_box PF00505.19 EKX35457.1 - 9.1e-25 86.9 4.1 6.1e-14 52.2 0.0 2.1 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EKX35457.1 - 6e-19 68.4 5.1 2.8e-08 34.3 3.9 2.1 2 0 0 2 2 2 2 HMG-box domain YABBY PF04690.13 EKX35457.1 - 2.3e-05 25.0 0.0 0.033 14.7 0.0 2.1 1 1 1 2 2 2 2 YABBY protein Catalase-rel PF06628.12 EKX35457.1 - 0.0041 17.3 0.6 1.5 9.0 0.1 2.7 2 0 0 2 2 2 2 Catalase-related immune-responsive DUF3106 PF11304.8 EKX35457.1 - 0.077 13.5 4.3 1.5 9.4 4.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) Ribosomal_L18 PF17135.4 EKX35458.1 - 5.9e-82 273.6 1.4 7e-82 273.4 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EKX35458.1 - 0.0032 18.2 0.0 0.0086 16.7 0.0 1.8 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A GAF PF01590.26 EKX35462.1 - 7.8e-10 39.5 0.0 8.8e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 EKX35462.1 - 1.1e-05 25.7 0.0 1.7e-05 25.1 0.0 1.3 1 1 0 1 1 1 1 GAF domain Transglut_core3 PF13471.6 EKX35462.1 - 0.013 15.4 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 Transglutaminase-like superfamily GAF_3 PF13492.6 EKX35462.1 - 0.061 13.7 0.0 0.076 13.4 0.0 1.3 1 0 0 1 1 1 0 GAF domain PDZ_2 PF13180.6 EKX35464.1 - 0.21 11.9 0.1 0.31 11.4 0.1 1.3 1 0 0 1 1 1 0 PDZ domain DUF3412 PF11892.8 EKX35465.1 - 0.031 14.4 0.6 0.041 14.0 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3412) UPF0449 PF15136.6 EKX35465.1 - 3.9 8.0 8.0 31 5.1 8.0 2.0 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 DSPn PF14671.6 EKX35466.1 - 4.5e-38 130.9 0.1 1.7e-36 125.7 0.0 2.4 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EKX35466.1 - 1.8e-16 60.2 0.0 2.1e-14 53.5 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX35466.1 - 7.9e-07 28.9 0.0 1.2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX35466.1 - 3e-06 27.5 0.0 4.3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EKX35466.1 - 0.00083 19.4 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EKX35466.1 - 0.059 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PP2C PF00481.21 EKX35467.1 - 1.3e-55 188.9 0.0 1.8e-55 188.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Suf PF05843.14 EKX35468.1 - 0.24 11.3 16.5 0.44 10.5 16.5 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Phage_TAC_8 PF10666.9 EKX35468.1 - 0.31 11.3 13.6 0.048 13.9 9.3 1.9 2 0 0 2 2 2 0 Phage tail assembly chaperone protein Gp14 ()A118 cEGF PF12662.7 EKX35468.1 - 0.45 10.5 3.4 4.3 7.3 1.3 2.5 2 0 0 2 2 2 0 Complement Clr-like EGF-like EGF_2 PF07974.13 EKX35468.1 - 1.4 9.3 6.0 0.26 11.7 1.5 2.1 2 0 0 2 2 2 0 EGF-like domain Macoilin PF09726.9 EKX35468.1 - 2.4 6.6 36.5 3.3 6.1 36.5 1.1 1 0 0 1 1 1 0 Macoilin family EGF_3 PF12947.7 EKX35468.1 - 7 6.9 8.2 0.22 11.8 1.1 2.2 3 0 0 3 3 3 0 EGF domain PH PF00169.29 EKX35469.1 - 0.0008 19.9 0.0 0.0016 18.9 0.0 1.5 1 0 0 1 1 1 1 PH domain TFIIA PF03153.13 EKX35469.1 - 0.014 15.4 1.5 0.013 15.5 1.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CENP-B_dimeris PF09026.10 EKX35469.1 - 1.3 9.4 21.3 2.9 8.4 21.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 EKX35469.1 - 4.7 5.2 14.7 6.8 4.7 14.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi MMR_HSR1 PF01926.23 EKX35470.1 - 0.0029 17.7 2.5 0.0054 16.8 0.1 2.7 3 1 0 3 3 3 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EKX35470.1 - 0.017 15.0 2.4 0.028 14.3 0.3 2.7 2 1 0 2 2 2 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 EKX35470.1 - 0.026 13.9 0.7 0.085 12.2 0.7 1.9 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 EKX35470.1 - 0.041 13.6 0.4 0.096 12.4 0.4 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 EKX35470.1 - 0.044 14.2 0.0 0.15 12.5 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 EKX35470.1 - 0.049 13.0 0.3 0.11 11.9 0.3 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 EKX35470.1 - 0.051 14.1 0.1 0.051 14.1 0.1 3.2 3 1 0 3 3 3 0 ABC transporter AAA_7 PF12775.7 EKX35470.1 - 0.083 12.4 1.4 0.58 9.7 0.2 2.7 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_16 PF13191.6 EKX35470.1 - 0.096 13.1 0.1 0.096 13.1 0.1 4.9 5 2 0 5 5 5 0 AAA ATPase domain DUF3619 PF12279.8 EKX35470.1 - 0.1 12.9 5.3 2.3 8.6 0.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) CdiA_C_tRNase PF18664.1 EKX35470.1 - 0.13 12.5 0.7 0.59 10.3 0.1 2.5 2 0 0 2 2 2 0 CdiA C-terminal tRNase domain AAA_22 PF13401.6 EKX35470.1 - 0.19 12.0 0.0 0.19 12.0 0.0 4.6 5 0 0 5 5 5 0 AAA domain ER PF01133.17 EKX35470.1 - 1.8 8.6 4.1 1.3 9.1 0.1 2.6 3 0 0 3 3 3 0 Enhancer of rudimentary RsgA_GTPase PF03193.16 EKX35471.1 - 9.8e-06 25.6 0.4 6.6e-05 22.9 0.4 2.5 1 1 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 EKX35471.1 - 0.00059 19.9 0.5 0.0034 17.4 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF3619 PF12279.8 EKX35471.1 - 0.023 15.0 3.3 2.5 8.4 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) AAA_29 PF13555.6 EKX35471.1 - 0.025 14.3 0.1 0.055 13.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 EKX35471.1 - 0.035 13.5 2.1 0.041 13.2 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 EKX35471.1 - 0.045 14.1 0.0 0.19 12.1 0.0 2.2 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 EKX35471.1 - 0.047 13.1 0.3 0.11 11.9 0.3 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EKX35471.1 - 0.061 12.8 0.2 0.77 9.2 0.2 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 EKX35471.1 - 0.077 13.5 0.1 0.077 13.5 0.1 3.8 3 1 0 4 4 4 0 ABC transporter AAA_16 PF13191.6 EKX35471.1 - 0.089 13.2 0.0 0.089 13.2 0.0 4.4 4 2 0 4 4 4 0 AAA ATPase domain AAA_24 PF13479.6 EKX35471.1 - 0.49 10.1 3.6 1.2 8.8 0.1 3.2 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 EKX35471.1 - 1.2 9.4 10.5 0.98 9.7 0.1 4.4 4 0 0 4 4 4 0 AAA domain GTP_EFTU PF00009.27 EKX35471.1 - 2.7 7.5 6.9 0.46 10.0 0.6 3.0 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain tRNA-synt_1g PF09334.11 EKX35472.1 - 3.8e-88 295.9 0.0 1.2e-85 287.6 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA_bind PF01588.20 EKX35472.1 - 3.4e-35 120.0 0.1 5.8e-35 119.3 0.1 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1 PF00133.22 EKX35472.1 - 6.2e-22 77.6 6.0 3.7e-11 42.0 0.0 4.5 2 1 2 4 4 4 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EKX35472.1 - 9.7e-13 48.1 1.9 2.7e-05 23.7 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 EKX35472.1 - 4.8e-05 23.4 0.2 9.5e-05 22.4 0.2 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DUF2722 PF10846.8 EKX35472.1 - 0.00078 18.5 1.7 0.001 18.1 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) MAS20 PF02064.15 EKX35472.1 - 0.064 13.4 2.6 0.13 12.3 2.6 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor Spt20 PF12090.8 EKX35472.1 - 0.092 12.3 7.6 0.14 11.7 7.6 1.2 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 EKX35472.1 - 2.5 7.1 6.8 4.2 6.4 6.8 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Coilin_N PF15862.5 EKX35472.1 - 3.3 7.5 8.4 6 6.7 8.4 1.3 1 0 0 1 1 1 0 Coilin N-terminus Pentapeptide PF00805.22 EKX35473.1 - 7.4e-16 57.5 2.2 1.9e-08 33.8 0.4 3.7 2 1 0 3 3 3 2 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 EKX35473.1 - 4.4e-07 30.0 0.1 8.9e-07 29.0 0.1 1.6 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 EKX35473.1 - 3.5e-05 23.9 4.0 0.00021 21.4 0.7 3.2 3 1 0 3 3 3 1 Pentapeptide repeats (9 copies) Myb_DNA-binding PF00249.31 EKX35476.1 - 9.8e-08 32.1 1.5 9.8e-08 32.1 1.5 2.6 2 1 0 2 2 2 1 Myb-like DNA-binding domain TEA PF01285.18 EKX35476.1 - 0.022 14.9 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 TEA/ATTS domain Pkinase PF00069.25 EKX35477.1 - 2.6e-52 177.8 0.1 3.5e-52 177.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX35477.1 - 2e-31 109.2 0.0 5.6e-31 107.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX35477.1 - 1.3e-06 27.5 0.4 1.9e-06 26.9 0.4 1.4 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EKX35477.1 - 1.7e-05 23.9 0.1 2.7e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EKX35477.1 - 2e-05 24.1 0.0 0.019 14.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 EKX35477.1 - 0.0081 15.8 0.3 0.013 15.1 0.3 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EKX35477.1 - 0.0095 15.3 0.3 0.017 14.5 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EKX35477.1 - 0.022 13.9 0.2 0.045 12.8 0.2 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 EKX35477.1 - 0.078 12.9 0.3 0.22 11.4 0.2 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF2236 PF09995.9 EKX35478.1 - 5.3e-34 118.4 0.0 8e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Myb_DNA-binding PF00249.31 EKX35481.1 - 1.6e-08 34.6 0.3 4.2e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EKX35481.1 - 0.011 15.5 0.2 0.024 14.6 0.1 1.5 1 1 0 1 1 1 0 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 EKX35481.1 - 0.074 13.3 0.0 0.074 13.3 0.0 2.8 5 0 0 5 5 5 0 Myb-like DNA-binding domain MTS PF05175.14 EKX35482.1 - 2.7e-11 43.3 0.0 6.9e-11 42.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EKX35482.1 - 3.3e-10 40.5 0.0 1.1e-08 35.7 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX35482.1 - 5.6e-09 36.0 0.0 7.9e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EKX35482.1 - 4.4e-07 29.6 0.0 6.8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 EKX35482.1 - 1.8e-06 27.8 0.0 6.7e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 EKX35482.1 - 2.4e-06 27.5 0.0 4.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_10 PF05971.12 EKX35482.1 - 1.4e-05 24.7 0.1 3.5e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 RNA methyltransferase Methyltransf_12 PF08242.12 EKX35482.1 - 3e-05 24.7 0.0 0.00094 19.9 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX35482.1 - 5.9e-05 23.7 0.0 0.0023 18.6 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX35482.1 - 0.00013 21.9 0.0 0.0016 18.3 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EKX35482.1 - 0.00031 20.5 0.0 0.00055 19.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.19 EKX35482.1 - 0.0015 18.3 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 EKX35482.1 - 0.0028 17.4 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PRMT5 PF05185.16 EKX35482.1 - 0.005 16.7 0.0 0.0084 16.0 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase RrnaAD PF00398.20 EKX35482.1 - 0.0087 15.2 0.0 0.071 12.2 0.0 1.9 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.17 EKX35482.1 - 0.014 14.8 0.1 0.04 13.4 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_15 PF09445.10 EKX35482.1 - 0.023 14.3 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.6 EKX35482.1 - 0.031 14.3 0.0 0.041 13.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 EKX35482.1 - 0.044 13.5 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase CMAS PF02353.20 EKX35482.1 - 0.056 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TrmK PF04816.12 EKX35482.1 - 0.09 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase Methyltransf_3 PF01596.17 EKX35482.1 - 0.11 11.6 0.0 0.86 8.7 0.0 2.0 2 0 0 2 2 2 0 O-methyltransferase DNA_pol_viral_N PF00242.17 EKX35483.1 - 1.7 8.1 7.5 2 7.8 7.5 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain PH PF00169.29 EKX35484.1 - 4.6e-05 23.9 0.1 0.00017 22.1 0.0 1.9 2 0 0 2 2 2 1 PH domain EspF PF04806.12 EKX35484.1 - 1.5 9.3 5.3 0.89 10.0 3.1 1.7 2 0 0 2 2 2 0 EspF protein repeat HPP PF04982.13 EKX35485.1 - 4.9e-15 55.8 0.6 9.6e-15 54.8 0.6 1.5 1 0 0 1 1 1 1 HPP family Ribosomal_60s PF00428.19 EKX35485.1 - 0.078 13.6 10.9 0.27 11.8 10.5 2.2 2 0 0 2 2 1 0 60s Acidic ribosomal protein DUF2093 PF09866.9 EKX35485.1 - 0.13 11.7 0.3 0.25 10.8 0.3 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) Med15 PF09606.10 EKX35485.1 - 0.47 9.1 27.8 0.69 8.5 27.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CPSF100_C PF13299.6 EKX35485.1 - 0.87 9.8 9.7 5.4 7.2 10.7 1.9 2 0 0 2 2 1 0 Cleavage and polyadenylation factor 2 C-terminal Dicty_REP PF05086.12 EKX35485.1 - 1 7.3 4.3 1.3 6.9 4.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TERB2 PF15101.6 EKX35485.1 - 1.2 9.2 12.9 2.8 8.0 12.9 1.6 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DDHD PF02862.17 EKX35485.1 - 1.3 9.2 8.6 0.39 10.8 5.4 1.9 2 0 0 2 2 2 0 DDHD domain Sporozoite_P67 PF05642.11 EKX35485.1 - 1.8 6.5 10.8 2.6 6.0 10.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Plasmodium_Vir PF05795.11 EKX35485.1 - 1.9 7.9 8.8 3.2 7.1 8.8 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PAT1 PF09770.9 EKX35485.1 - 1.9 6.7 20.7 3.4 5.8 20.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 EKX35485.1 - 1.9 5.5 13.8 2.6 5.1 13.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer eIF-3_zeta PF05091.12 EKX35485.1 - 1.9 7.4 16.7 3.3 6.6 16.7 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TFIIA PF03153.13 EKX35485.1 - 2.9 7.8 30.1 0.081 12.9 23.9 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 EKX35485.1 - 3.5 8.3 19.7 25 5.5 19.1 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Coilin_N PF15862.5 EKX35485.1 - 4.1 7.2 12.3 12 5.7 12.3 1.8 1 0 0 1 1 1 0 Coilin N-terminus PPP4R2 PF09184.11 EKX35485.1 - 4.8 6.7 13.8 8.7 5.8 13.8 1.4 1 0 0 1 1 1 0 PPP4R2 RR_TM4-6 PF06459.12 EKX35485.1 - 5.4 6.8 17.4 11 5.7 17.4 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PBP_sp32 PF07222.12 EKX35485.1 - 5.5 6.4 22.0 2.7 7.4 18.1 2.2 2 0 0 2 2 2 0 Proacrosin binding protein sp32 Spore_coat_CotO PF14153.6 EKX35485.1 - 8.4 6.3 25.0 18 5.2 25.0 1.5 1 0 0 1 1 1 0 Spore coat protein CotO FYDLN_acid PF09538.10 EKX35485.1 - 8.7 7.1 13.3 28 5.4 12.6 2.4 2 0 0 2 2 1 0 Protein of unknown function (FYDLN_acid) Spt20 PF12090.8 EKX35485.1 - 9.1 5.8 28.2 18 4.9 28.2 1.5 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 EKX35485.1 - 9.8 4.8 19.4 17 4.1 19.4 1.3 1 0 0 1 1 1 0 Presenilin AstE_AspA PF04952.14 EKX35486.1 - 2e-28 99.3 0.1 7.8e-25 87.5 0.0 3.1 3 0 0 3 3 3 3 Succinylglutamate desuccinylase / Aspartoacylase family CE2_N PF17996.1 EKX35487.1 - 0.079 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal L_biotic_typeA PF04604.13 EKX35488.1 - 0.02 14.8 0.3 0.043 13.7 0.0 1.7 2 0 0 2 2 2 0 Type-A lantibiotic Dynamin_N PF00350.23 EKX35490.1 - 0.0001 22.4 2.0 0.00023 21.3 0.0 2.4 2 1 0 2 2 2 1 Dynamin family Nitr_red_assoc PF09655.10 EKX35490.1 - 0.00037 21.2 1.0 0.31 11.7 0.4 2.4 2 0 0 2 2 2 2 Conserved nitrate reductase-associated protein (Nitr_red_assoc) Toprim_4 PF13662.6 EKX35490.1 - 0.00064 20.1 0.1 0.5 10.9 0.0 2.9 3 0 0 3 3 3 2 Toprim domain AIG1 PF04548.16 EKX35490.1 - 0.0022 17.4 0.4 1.4 8.2 0.0 2.5 2 0 0 2 2 2 2 AIG1 family MMR_HSR1 PF01926.23 EKX35490.1 - 0.0085 16.2 0.1 0.03 14.4 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF2894 PF11445.8 EKX35490.1 - 0.66 10.4 7.2 0.37 11.2 4.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) Aida_N PF08910.10 EKX35490.1 - 0.89 10.0 4.5 0.68 10.4 1.4 2.3 1 1 2 3 3 3 0 Aida N-terminus Phage_HK97_TLTM PF06120.11 EKX35492.1 - 0.024 13.8 2.1 0.038 13.2 2.1 1.3 1 0 0 1 1 1 0 Tail length tape measure protein PH PF00169.29 EKX35492.1 - 0.16 12.5 0.0 0.45 11.0 0.0 1.8 2 0 0 2 2 2 0 PH domain CENP-F_leu_zip PF10473.9 EKX35492.1 - 2.4 8.2 16.9 3.7 7.6 1.0 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Plant_tran PF04827.14 EKX35495.1 - 3.3e-12 46.5 0.0 4.2e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_4 PF13359.6 EKX35495.1 - 5.8e-09 35.8 0.1 7.9e-09 35.4 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EKX35495.1 - 0.16 11.6 0.1 0.31 10.7 0.1 1.4 1 0 0 1 1 1 0 Transposase DDE domain KduI PF04962.12 EKX35496.1 - 0.2 11.0 0.5 0.26 10.5 0.4 1.3 1 1 0 1 1 1 0 KduI/IolB family Methyltrn_RNA_4 PF09936.9 EKX35496.1 - 0.38 10.6 2.8 3.5 7.5 0.0 2.2 1 1 1 2 2 2 0 SAM-dependent RNA methyltransferase EphA2_TM PF14575.6 EKX35498.1 - 0.048 14.5 0.1 0.55 11.1 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain HSP70 PF00012.20 EKX35501.1 - 6.1e-200 665.4 2.4 7.3e-200 665.1 2.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EKX35501.1 - 8.9e-17 60.9 0.7 1.5e-16 60.1 0.2 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 EKX35501.1 - 0.00069 20.0 1.7 0.24 11.8 0.0 3.4 3 2 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 EKX35501.1 - 0.0052 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 EKX35501.1 - 0.012 15.2 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family PX PF00787.24 EKX35502.1 - 1.5e-19 70.0 0.1 2e-19 69.7 0.1 1.1 1 0 0 1 1 1 1 PX domain SF3A3 PF16837.5 EKX35503.1 - 2.6e-21 75.9 2.8 3.2e-21 75.6 0.9 2.2 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 EKX35503.1 - 5.8e-10 38.9 0.0 1.4e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain PDZ_6 PF17820.1 EKX35503.1 - 2.1e-08 33.9 0.2 4.4e-08 32.9 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX35503.1 - 1.4e-07 31.8 0.1 3.1e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX35503.1 - 4.7e-07 30.0 0.0 1.5e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX35503.1 - 0.15 12.1 0.1 0.41 10.7 0.1 1.7 1 0 0 1 1 1 0 Tricorn protease PDZ domain PPR PF01535.20 EKX35503.1 - 0.46 10.8 1.5 1.2 9.5 0.1 2.4 2 0 0 2 2 2 0 PPR repeat PDZ_6 PF17820.1 EKX35504.1 - 3e-09 36.6 0.4 5.4e-09 35.8 0.4 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX35504.1 - 2.5e-07 31.0 0.0 4.8e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX35504.1 - 2e-06 28.0 0.0 3.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX35504.1 - 0.01 15.8 0.1 0.021 14.8 0.1 1.6 1 1 0 1 1 1 0 Tricorn protease PDZ domain Aminotran_1_2 PF00155.21 EKX35506.1 - 7.5e-89 298.4 0.0 8.6e-89 298.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II PDZ PF00595.24 EKX35507.1 - 0.0035 17.7 0.0 0.013 15.9 0.0 2.0 1 1 0 1 1 1 1 PDZ domain ZnuA PF01297.17 EKX35507.1 - 0.023 14.1 0.5 0.032 13.7 0.5 1.4 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic Seadorna_VP6 PF07407.11 EKX35507.1 - 0.059 12.3 1.5 0.086 11.8 1.5 1.2 1 0 0 1 1 1 0 Seadornavirus VP6 protein Anoct_dimer PF16178.5 EKX35507.1 - 0.14 11.9 8.6 0.23 11.1 8.6 1.3 1 0 0 1 1 1 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin TFIIA PF03153.13 EKX35507.1 - 0.26 11.3 13.0 0.29 11.1 13.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1359 PF07097.11 EKX35507.1 - 0.32 11.3 4.2 2.2 8.6 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1359) NPV_P10 PF05531.12 EKX35507.1 - 0.4 11.2 5.3 0.2 12.1 1.0 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 EKX35507.1 - 2.9 8.2 14.7 4.7 7.6 6.5 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fez1 PF06818.15 EKX35507.1 - 4 7.8 23.3 2.6 8.4 5.9 2.2 1 1 1 2 2 2 0 Fez1 Exonuc_VII_L PF02601.15 EKX35507.1 - 7.5 6.0 12.2 11 5.4 12.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit RPE65 PF03055.15 EKX35508.1 - 1.9e-90 304.3 0.0 2.3e-90 304.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Secretin_N PF03958.17 EKX35510.1 - 0.15 12.5 0.0 0.24 11.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial type II/III secretion system short domain HTH_Tnp_Tc5 PF03221.16 EKX35511.1 - 7.6e-06 25.9 0.0 4.1e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 EKX35511.1 - 0.00028 20.5 0.5 0.00067 19.2 0.5 1.7 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain Sigma70_r4 PF04545.16 EKX35511.1 - 0.0065 16.0 0.4 0.03 13.8 0.0 2.3 3 0 0 3 3 3 1 Sigma-70, region 4 alpha-hel2 PF14456.6 EKX35511.1 - 0.015 14.6 2.5 0.023 14.0 2.5 1.2 1 0 0 1 1 1 0 Alpha-helical domain 2 HTH_23 PF13384.6 EKX35511.1 - 0.017 14.9 0.2 0.072 12.9 0.1 2.1 2 0 0 2 2 2 0 Homeodomain-like domain GrpE PF01025.19 EKX35511.1 - 0.036 13.7 3.9 0.054 13.2 3.9 1.2 1 0 0 1 1 1 0 GrpE HTH_38 PF13936.6 EKX35511.1 - 0.1 12.4 0.4 0.58 10.0 0.4 2.2 1 1 0 1 1 1 0 Helix-turn-helix domain HSP70 PF00012.20 EKX35511.1 - 0.27 9.4 3.3 0.34 9.0 3.3 1.1 1 0 0 1 1 1 0 Hsp70 protein Ribosomal_L11 PF00298.19 EKX35511.1 - 0.75 10.3 6.6 5.9 7.5 1.0 3.1 2 1 1 3 3 3 0 Ribosomal protein L11, RNA binding domain Glyco_transf_49 PF13896.6 EKX35512.1 - 7.8e-28 97.8 1.6 1e-10 41.5 0.6 3.4 2 1 1 3 3 3 3 Glycosyl-transferase for dystroglycan C2 PF00168.30 EKX35512.1 - 3.5e-09 36.9 0.0 9.1e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 C2 domain LRR_6 PF13516.6 EKX35512.1 - 4e-06 26.5 4.5 0.0025 17.7 0.1 5.3 5 0 0 5 5 5 1 Leucine Rich repeat WW PF00397.26 EKX35512.1 - 9.8e-06 25.6 0.1 9.8e-06 25.6 0.1 3.6 4 0 0 4 4 4 2 WW domain DZR PF12773.7 EKX35512.1 - 0.00051 20.0 1.4 0.0012 18.8 1.4 1.6 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 EKX35512.1 - 0.18 11.5 12.9 0.017 14.8 8.1 1.9 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 EKX35512.1 - 9.9 7.0 6.1 23 5.8 6.1 1.6 1 0 0 1 1 1 0 zinc-ribbon family Spectrin PF00435.21 EKX35513.1 - 0.11 13.0 4.5 0.057 13.9 2.6 1.4 2 0 0 2 2 2 0 Spectrin repeat Spc24 PF08286.11 EKX35513.1 - 0.14 12.4 1.9 0.21 11.9 1.9 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF826 PF05696.11 EKX35513.1 - 0.19 11.9 2.2 9.6 6.4 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF826) FlxA PF14282.6 EKX35513.1 - 1 9.4 10.8 0.97 9.5 8.3 2.1 1 1 1 2 2 2 0 FlxA-like protein DivIC PF04977.15 EKX35513.1 - 1 9.2 6.8 0.96 9.3 2.2 2.2 1 1 1 2 2 2 0 Septum formation initiator WD40 PF00400.32 EKX35514.1 - 1.1e-18 67.3 20.1 1.2e-06 29.1 1.1 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EKX35514.1 - 0.00016 20.8 0.1 0.00031 19.8 0.1 1.4 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EKX35514.1 - 0.39 9.3 4.0 4.8 5.7 0.2 3.0 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Bestrophin PF01062.21 EKX35515.1 - 0.25 10.7 0.0 0.28 10.5 0.0 1.1 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel DUF5316 PF17247.2 EKX35516.1 - 2 8.5 5.4 1.1 9.3 0.1 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5316) LysM PF01476.20 EKX35517.1 - 8.5e-13 48.2 0.3 1.9e-05 24.7 0.0 2.6 3 0 0 3 3 3 2 LysM domain Ank_2 PF12796.7 EKX35519.1 - 0.00053 20.5 0.0 0.01 16.4 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX35519.1 - 0.00084 19.9 0.0 0.0023 18.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX35519.1 - 0.15 12.4 0.1 4.9 7.6 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Siva PF05458.12 EKX35519.1 - 0.16 11.6 12.4 0.081 12.6 10.0 1.7 2 0 0 2 2 2 0 Cd27 binding protein (Siva) CSD PF00313.22 EKX35520.1 - 1.2e-11 44.2 0.0 2.4e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain KHA PF11834.8 EKX35520.1 - 0.00041 20.4 0.0 0.019 15.0 0.0 2.6 2 0 0 2 2 2 1 KHA, dimerisation domain of potassium ion channel zf-CCCH_2 PF14608.6 EKX35520.1 - 0.0012 19.3 6.1 0.0021 18.4 6.1 1.4 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 EKX35520.1 - 0.025 14.7 1.1 0.025 14.7 1.1 1.8 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH_4 PF18044.1 EKX35520.1 - 0.04 13.7 3.6 0.069 13.0 3.6 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH PF00642.24 EKX35520.1 - 0.079 12.9 1.9 0.16 12.0 1.9 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) EAV_GS PF01309.18 EKX35520.1 - 0.15 11.7 0.1 0.43 10.2 0.0 1.7 2 0 0 2 2 2 0 Equine arteritis virus small envelope glycoprotein Nab2p_Zf1 PF18260.1 EKX35520.1 - 0.21 11.5 1.5 0.39 10.7 1.5 1.4 1 0 0 1 1 1 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 UBA PF00627.31 EKX35520.1 - 0.46 10.4 2.5 1.2 9.1 0.0 2.6 2 0 0 2 2 2 0 UBA/TS-N domain Ank_4 PF13637.6 EKX35521.1 - 7.7e-15 55.1 0.3 1.5e-09 38.2 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX35521.1 - 9.3e-14 51.2 1.0 2.2e-05 24.7 0.1 3.6 4 1 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EKX35521.1 - 1.1e-13 50.0 0.8 8.1e-05 22.7 0.0 4.1 5 0 0 5 5 5 2 Ankyrin repeat Ank_2 PF12796.7 EKX35521.1 - 1.1e-13 51.5 0.0 1.1e-12 48.3 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX35521.1 - 2.1e-12 47.0 0.1 3.9e-06 27.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) cNMP_binding PF00027.29 EKX35523.1 - 5.4e-16 58.4 0.0 7.2e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF4665 PF15679.5 EKX35525.1 - 0.032 14.8 1.5 0.11 13.2 1.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4665) INTS5_N PF14837.6 EKX35525.1 - 0.084 12.5 1.0 1.7 8.2 0.4 2.5 2 0 0 2 2 2 0 Integrator complex subunit 5 N-terminus DUF745 PF05335.13 EKX35525.1 - 0.15 11.7 4.8 0.38 10.5 4.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Mt_ATP-synt_D PF05873.12 EKX35525.1 - 0.17 11.7 3.6 0.59 10.0 2.8 2.4 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) RasGAP_C PF03836.15 EKX35525.1 - 0.59 10.3 8.3 0.27 11.4 3.8 2.3 2 0 0 2 2 2 0 RasGAP C-terminus DUF4407 PF14362.6 EKX35525.1 - 0.63 9.3 8.4 0.96 8.7 6.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4140 PF13600.6 EKX35525.1 - 0.79 10.2 4.4 8.4 6.9 2.3 2.8 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) XhlA PF10779.9 EKX35525.1 - 2.3 8.5 5.5 4.4 7.6 2.9 2.7 2 0 0 2 2 2 0 Haemolysin XhlA FAM76 PF16046.5 EKX35525.1 - 8.6 5.6 11.0 20 4.4 11.0 1.6 1 0 0 1 1 1 0 FAM76 protein Ion_trans PF00520.31 EKX35526.1 - 6.4e-33 114.0 17.3 9.8e-33 113.4 17.3 1.1 1 0 0 1 1 1 1 Ion transport protein EF-hand_1 PF00036.32 EKX35526.1 - 1.9e-13 48.9 6.3 0.00049 19.4 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EKX35526.1 - 1.8e-12 46.1 0.2 0.015 15.2 0.0 4.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 EKX35526.1 - 1.3e-11 44.8 1.8 2.4e-07 31.1 0.3 3.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX35526.1 - 4.2e-09 35.5 3.4 0.0036 16.7 0.1 3.8 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EKX35526.1 - 2.6e-08 33.6 5.6 0.00026 20.8 0.1 4.2 3 1 1 4 4 4 2 EF-hand domain pair PKD_channel PF08016.12 EKX35526.1 - 3.4e-08 32.6 9.8 8.2e-07 28.0 4.0 2.2 2 0 0 2 2 2 2 Polycystin cation channel PH PF00169.29 EKX35526.1 - 5.6e-06 26.8 0.0 1e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 PH domain P_C10 PF14974.6 EKX35526.1 - 0.041 14.0 0.0 0.13 12.4 0.0 1.9 1 0 0 1 1 1 0 Protein C10 SPARC_Ca_bdg PF10591.9 EKX35526.1 - 0.076 13.3 0.1 0.32 11.3 0.0 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region SRF-TF PF00319.18 EKX35528.1 - 1.9e-17 62.5 0.1 2.6e-17 62.0 0.1 1.3 1 1 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) SK_channel PF03530.14 EKX35529.1 - 2.3e-05 24.4 1.9 2.3e-05 24.4 1.9 2.4 2 2 0 2 2 2 1 Calcium-activated SK potassium channel DUF2730 PF10805.8 EKX35529.1 - 0.16 12.1 5.1 0.056 13.5 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Perilipin PF03036.16 EKX35530.1 - 0.14 11.2 0.1 0.16 11.0 0.1 1.0 1 0 0 1 1 1 0 Perilipin family Adaptin_N PF01602.20 EKX35531.1 - 2e-124 416.0 10.5 2.7e-124 415.6 10.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region AP3B1_C PF14796.6 EKX35531.1 - 9.1e-20 71.4 0.1 3.3e-19 69.6 0.1 2.0 2 0 0 2 2 2 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Cnd1 PF12717.7 EKX35531.1 - 2.8e-19 69.7 6.5 2.7e-17 63.3 0.0 3.3 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EKX35531.1 - 7.2e-07 29.5 3.4 5.1e-05 23.6 0.3 3.2 2 1 0 2 2 2 2 HEAT repeats HEAT PF02985.22 EKX35531.1 - 2.4e-06 27.3 0.4 0.38 11.1 0.1 4.5 3 0 0 3 3 3 3 HEAT repeat HEAT_EZ PF13513.6 EKX35531.1 - 0.047 14.2 3.7 7.1 7.2 0.1 4.7 3 2 2 5 5 5 0 HEAT-like repeat Pkinase PF00069.25 EKX35532.1 - 9.7e-68 228.4 0.0 1.2e-67 228.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX35532.1 - 2.8e-39 134.9 0.0 3.4e-39 134.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX35532.1 - 0.00023 20.6 0.0 0.02 14.2 0.0 2.3 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 EKX35532.1 - 0.0085 15.5 0.1 0.024 14.0 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ral PF11058.8 EKX35532.1 - 0.17 11.5 0.0 12 5.6 0.0 2.9 3 0 0 3 3 3 0 Antirestriction protein Ral ANAPC1 PF12859.7 EKX35535.1 - 1.6e-09 38.4 0.0 3e-05 24.6 0.0 3.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 EKX35535.1 - 1.7e-05 25.0 11.9 0.8 10.3 0.0 4.8 4 0 0 4 4 4 3 Proteasome/cyclosome repeat DnaJ PF00226.31 EKX35537.1 - 6e-12 45.5 0.4 1.8e-11 44.0 0.4 1.7 1 0 0 1 1 1 1 DnaJ domain GYF_2 PF14237.6 EKX35537.1 - 9.5e-06 25.3 0.0 2.4e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 GYF domain 2 WD40 PF00400.32 EKX35538.1 - 3.9e-87 283.8 63.6 4.6e-08 33.6 0.6 13.1 13 0 0 13 13 13 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX35538.1 - 8.3e-19 67.7 11.8 0.21 11.9 0.0 8.8 2 1 6 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EKX35538.1 - 1.7e-10 40.2 16.4 1.2 7.7 0.0 10.0 4 4 7 11 11 11 3 Nucleoporin Nup120/160 WD40_like PF17005.5 EKX35538.1 - 1e-05 25.1 0.0 0.19 11.0 0.0 4.1 3 1 1 4 4 4 2 WD40-like domain DUF1513 PF07433.11 EKX35538.1 - 0.00091 18.4 13.3 0.0047 16.1 0.2 4.8 2 1 3 6 6 6 2 Protein of unknown function (DUF1513) Me-amine-dh_H PF06433.11 EKX35538.1 - 0.0014 17.6 0.0 19 4.0 0.0 4.5 5 1 1 6 6 6 0 Methylamine dehydrogenase heavy chain (MADH) Big_4 PF07532.11 EKX35538.1 - 0.0032 17.2 1.0 1.4 8.7 0.1 2.8 2 0 0 2 2 2 2 Bacterial Ig-like domain (group 4) VID27 PF08553.10 EKX35538.1 - 0.0036 16.4 0.8 0.63 9.0 0.0 3.6 3 1 2 5 5 5 1 VID27 C-terminal WD40-like domain Nucleoporin_N PF08801.11 EKX35538.1 - 0.0089 14.8 0.0 13 4.4 0.0 4.1 2 1 4 6 6 6 1 Nup133 N terminal like CPSF_A PF03178.15 EKX35538.1 - 0.017 14.4 0.1 0.18 11.1 0.0 2.8 2 2 1 3 3 3 0 CPSF A subunit region HTH_49 PF18010.1 EKX35538.1 - 0.018 14.9 0.1 79 3.3 0.0 3.8 4 0 0 4 4 3 0 Cry35Ab1 HTH C-terminal domain DUF2620 PF10941.8 EKX35538.1 - 0.033 14.3 6.6 7.4 6.7 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function DUF2620 Desulfoferrod_N PF06397.12 EKX35538.1 - 0.08 12.6 3.9 3.7 7.3 0.2 3.1 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain DUF5642 PF18702.1 EKX35538.1 - 1.5 8.6 4.6 75 3.0 0.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF5642) UPF0047 PF01894.17 EKX35539.1 - 1.3e-40 138.1 0.0 1.7e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 cNMP_binding PF00027.29 EKX35540.1 - 2e-33 114.3 0.1 6.3e-16 58.2 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain HEPN PF05168.14 EKX35540.1 - 0.056 13.6 0.4 0.22 11.7 0.1 2.1 1 1 1 2 2 2 0 HEPN domain COBRA1 PF06209.13 EKX35540.1 - 0.093 11.6 0.2 34 3.1 0.0 3.0 3 0 0 3 3 3 0 Cofactor of BRCA1 (COBRA1) YfdX PF10938.8 EKX35540.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 YfdX protein DUF5552 PF17706.1 EKX35541.1 - 0.011 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5552) Dus PF01207.17 EKX35542.1 - 1.6e-48 165.4 0.0 1.3e-40 139.4 0.0 2.0 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) MAGE PF01454.19 EKX35544.1 - 0.019 14.7 0.2 0.028 14.1 0.2 1.3 1 0 0 1 1 1 0 MAGE family AvrM-A PF18241.1 EKX35544.1 - 0.021 15.2 0.2 0.077 13.4 0.2 1.8 1 1 0 1 1 1 0 Flax-rust effector AvrM-A RNase_E_G PF10150.9 EKX35544.1 - 0.037 13.5 0.4 0.04 13.3 0.4 1.1 1 0 0 1 1 1 0 Ribonuclease E/G family Trypsin_2 PF13365.6 EKX35545.1 - 3.3e-06 28.1 0.0 0.037 14.9 0.0 2.7 2 0 0 2 2 2 2 Trypsin-like peptidase domain PIP5K PF01504.18 EKX35545.1 - 0.0045 16.3 0.1 0.0089 15.3 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Peptidase_S46 PF10459.9 EKX35545.1 - 0.012 14.3 6.3 0.07 11.8 0.0 2.2 2 0 0 2 2 2 0 Peptidase S46 SpoIIP PF07454.11 EKX35545.1 - 0.03 13.8 12.5 0.063 12.7 12.5 1.6 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Peptidase_S32 PF05579.13 EKX35545.1 - 0.093 11.9 0.1 0.37 9.9 0.0 1.8 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Trypsin PF00089.26 EKX35545.1 - 0.12 12.2 0.7 8.3 6.1 0.0 3.4 3 1 1 4 4 4 0 Trypsin PDZ_6 PF17820.1 EKX35545.1 - 0.12 12.3 0.1 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 PDZ domain Otopetrin PF03189.13 EKX35545.1 - 0.62 8.8 2.9 0.77 8.5 2.9 1.2 1 0 0 1 1 1 0 Otopetrin DUF4407 PF14362.6 EKX35545.1 - 2.4 7.4 16.8 3.7 6.8 16.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 EKX35545.1 - 3.3 7.6 29.3 4.9 7.1 29.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MMU163 PF17119.5 EKX35545.1 - 3.4 6.8 11.2 2.5 7.2 7.4 2.1 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis NPR3 PF03666.13 EKX35545.1 - 3.7 6.2 14.6 6.1 5.5 14.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SID-1_RNA_chan PF13965.6 EKX35545.1 - 4.3 5.6 7.2 6.5 5.0 7.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CLN3 PF02487.17 EKX35545.1 - 5.4 5.9 9.5 8.4 5.3 9.5 1.2 1 0 0 1 1 1 0 CLN3 protein UPF0560 PF10577.9 EKX35545.1 - 8.9 4.7 13.5 13 4.1 13.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Hid1 PF12722.7 EKX35545.1 - 8.9 4.3 14.1 12 3.8 14.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2828 PF11443.8 EKX35545.1 - 9.5 4.2 16.7 15 3.5 16.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) AIG2_2 PF13772.6 EKX35546.1 - 1.6e-07 31.6 0.0 2.3e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family GGACT PF06094.12 EKX35546.1 - 6.5e-05 23.5 0.0 0.00012 22.7 0.0 1.4 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like F_actin_cap_B PF01115.17 EKX35547.1 - 0.064 12.9 1.3 0.095 12.3 1.3 1.2 1 0 0 1 1 1 0 F-actin capping protein, beta subunit Tcf25 PF04910.14 EKX35547.1 - 0.092 11.8 1.9 0.12 11.5 1.9 1.2 1 0 0 1 1 1 0 Transcriptional repressor TCF25 Beta_helix PF13229.6 EKX35550.1 - 1.1e-07 31.8 0.1 4.1e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 Right handed beta helix region NosD PF05048.13 EKX35550.1 - 0.051 12.8 0.5 0.23 10.7 0.0 2.0 2 0 0 2 2 2 0 Periplasmic copper-binding protein (NosD) Fib_alpha PF08702.10 EKX35550.1 - 5.8 7.1 7.1 1.3 9.1 0.8 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CCCAP PF15964.5 EKX35552.1 - 0.00038 18.9 2.6 0.00041 18.8 2.6 1.0 1 0 0 1 1 1 1 Centrosomal colon cancer autoantigen protein family DUF3450 PF11932.8 EKX35552.1 - 0.0013 18.1 3.1 0.0014 18.0 3.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 EKX35552.1 - 0.0014 18.7 5.6 0.0015 18.5 5.6 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 EKX35552.1 - 0.0015 19.1 5.8 0.0016 19.0 5.8 1.0 1 0 0 1 1 1 1 Apg6 coiled-coil region ERM PF00769.19 EKX35552.1 - 0.0019 18.1 3.7 0.002 18.0 3.7 1.0 1 0 0 1 1 1 1 Ezrin/radixin/moesin family KxDL PF10241.9 EKX35552.1 - 0.0022 18.2 3.2 0.0022 18.2 3.2 1.5 1 1 1 2 2 2 1 Uncharacterized conserved protein DUF4472 PF14739.6 EKX35552.1 - 0.0041 17.8 3.3 0.0047 17.6 3.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4472) DUF4201 PF13870.6 EKX35552.1 - 0.0053 16.5 4.1 0.0057 16.4 4.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) YlqD PF11068.8 EKX35552.1 - 0.0064 16.9 3.2 0.0067 16.8 3.2 1.1 1 0 0 1 1 1 1 YlqD protein TPR_MLP1_2 PF07926.12 EKX35552.1 - 0.0069 16.5 3.7 0.0085 16.2 3.7 1.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.12 EKX35552.1 - 0.0076 16.3 0.8 0.0084 16.2 0.8 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus TACC_C PF05010.14 EKX35552.1 - 0.0092 15.8 4.0 0.012 15.5 4.0 1.0 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Filament PF00038.21 EKX35552.1 - 0.0097 15.5 2.2 0.01 15.5 2.2 1.1 1 0 0 1 1 1 1 Intermediate filament protein GAS PF13851.6 EKX35552.1 - 0.013 14.9 3.0 0.017 14.5 3.0 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TolA_bind_tri PF16331.5 EKX35552.1 - 0.016 15.3 6.0 0.27 11.3 0.9 2.2 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF1664 PF07889.12 EKX35552.1 - 0.026 14.5 1.9 0.034 14.2 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF1640 PF07798.11 EKX35552.1 - 0.034 14.2 3.1 0.038 14.0 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Spc7 PF08317.11 EKX35552.1 - 0.036 13.0 4.2 0.036 12.9 4.2 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2203 PF09969.9 EKX35552.1 - 0.05 14.3 0.7 0.053 14.2 0.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) YabA PF06156.13 EKX35552.1 - 0.091 13.4 1.7 0.12 13.1 1.7 1.3 1 0 0 1 1 1 0 Initiation control protein YabA HIP1_clath_bdg PF16515.5 EKX35552.1 - 0.094 13.3 6.2 0.15 12.7 5.0 1.4 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DASH_Dam1 PF08653.10 EKX35552.1 - 0.11 12.3 0.9 0.25 11.2 0.5 1.8 1 1 0 1 1 1 0 DASH complex subunit Dam1 TMF_DNA_bd PF12329.8 EKX35552.1 - 0.16 12.0 6.7 0.078 13.0 4.6 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Prefoldin_2 PF01920.20 EKX35552.1 - 0.86 9.6 8.0 2 8.4 0.7 2.1 1 1 1 2 2 2 0 Prefoldin subunit Spc24 PF08286.11 EKX35552.1 - 3.9 7.8 7.2 9.1 6.6 1.0 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 PDZ PF00595.24 EKX35553.1 - 5.3e-07 29.9 0.2 1.3e-06 28.6 0.1 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EKX35553.1 - 1.4e-06 28.1 0.0 2.7e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX35553.1 - 0.0077 16.5 0.1 0.021 15.1 0.1 1.7 1 0 0 1 1 1 1 PDZ domain Alph_Pro_TM PF09608.10 EKX35553.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) GRASP55_65 PF04495.14 EKX35553.1 - 0.16 12.3 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain K-box PF01486.17 EKX35553.1 - 1.3 9.2 5.3 1.5 9.0 0.6 2.6 2 0 0 2 2 2 0 K-box region TPR_2 PF07719.17 EKX35555.1 - 1.1e-39 131.3 5.1 0.00015 21.6 0.4 10.0 9 1 1 10 10 10 8 Tetratricopeptide repeat TPR_1 PF00515.28 EKX35555.1 - 4.2e-35 118.1 6.4 3.9e-07 29.6 0.1 8.8 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 EKX35555.1 - 5.3e-34 113.6 9.5 5.5e-06 26.2 0.2 8.7 10 0 0 10 10 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 EKX35555.1 - 4.5e-29 99.8 0.6 6.3e-09 35.4 0.0 7.8 6 2 2 8 8 8 6 TPR repeat TPR_12 PF13424.6 EKX35555.1 - 9.9e-23 80.2 13.6 4.8e-05 23.6 0.3 7.8 6 3 1 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.6 EKX35555.1 - 4e-20 72.1 1.5 0.0049 17.4 0.0 6.8 4 3 2 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 EKX35555.1 - 3.3e-19 67.8 3.9 0.11 13.0 0.0 8.6 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 EKX35555.1 - 5.1e-18 65.5 0.7 0.0026 18.4 0.5 5.7 4 1 1 6 6 5 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX35555.1 - 4.9e-16 58.7 5.8 0.0011 19.1 1.2 6.3 1 1 7 8 8 8 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EKX35555.1 - 6.3e-16 58.3 0.8 0.0012 18.9 0.0 5.7 2 2 5 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX35555.1 - 1.5e-15 56.6 6.6 0.013 16.3 0.0 8.0 5 3 5 10 10 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX35555.1 - 2.1e-12 46.1 4.8 0.0029 17.5 0.3 5.9 7 0 0 7 7 7 2 Tetratricopeptide repeat Wzy_C_2 PF11846.8 EKX35555.1 - 8e-10 39.0 0.4 0.018 15.0 0.5 4.0 3 1 1 4 4 4 3 Virulence factor membrane-bound polymerase, C-terminal TPR_6 PF13174.6 EKX35555.1 - 9.4e-09 35.4 6.6 0.22 12.2 0.2 8.5 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX35555.1 - 5e-08 32.6 13.5 0.0071 16.2 0.3 8.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_15 PF13429.6 EKX35555.1 - 3.1e-07 29.9 2.7 0.0027 17.0 0.4 3.9 1 1 0 3 3 3 2 Tetratricopeptide repeat NARP1 PF12569.8 EKX35555.1 - 1.3e-06 27.7 1.1 0.064 12.2 0.0 3.2 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_4 PF07721.14 EKX35555.1 - 0.0001 22.6 0.0 12 6.8 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX35555.1 - 0.00038 19.9 2.9 0.15 11.4 0.1 4.0 2 2 1 3 3 3 1 MalT-like TPR region Coatomer_E PF04733.14 EKX35555.1 - 0.0013 18.2 0.8 0.061 12.7 0.0 3.1 1 1 2 3 3 3 1 Coatomer epsilon subunit SNAP PF14938.6 EKX35555.1 - 0.011 15.1 3.7 2.1 7.7 0.0 3.4 4 1 0 4 4 4 0 Soluble NSF attachment protein, SNAP DUF4810 PF16068.5 EKX35555.1 - 0.013 16.1 1.2 1.9 9.1 0.1 3.8 3 2 0 3 3 3 0 Domain of unknown function (DUF4810) PknG_TPR PF16918.5 EKX35555.1 - 0.022 13.5 0.3 0.54 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein kinase G tetratricopeptide repeat SRP_TPR_like PF17004.5 EKX35555.1 - 0.025 14.6 2.4 15 5.7 0.2 3.6 2 2 0 2 2 2 0 Putative TPR-like repeat G6PD_bact PF10786.9 EKX35555.1 - 0.035 13.7 1.5 0.089 12.3 0.2 2.1 1 1 0 2 2 2 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) ChAPs PF09295.10 EKX35555.1 - 0.046 12.7 0.0 0.22 10.5 0.0 2.1 1 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.6 EKX35555.1 - 0.21 11.7 4.1 7 6.8 0.1 4.3 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat ANAPC5 PF12862.7 EKX35555.1 - 0.31 11.1 2.7 4.8 7.3 0.5 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 MIT PF04212.18 EKX35555.1 - 0.64 10.1 12.2 1.3 9.1 0.1 4.9 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain Acetyltransf_1 PF00583.25 EKX35556.1 - 2.2e-16 60.1 0.2 3.2e-16 59.6 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EKX35556.1 - 2.4e-10 40.4 0.0 3.7e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EKX35556.1 - 3e-08 34.0 0.2 5.1e-08 33.2 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EKX35556.1 - 1.7e-06 27.9 0.0 2.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EKX35556.1 - 4e-06 27.0 0.0 5.7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EKX35556.1 - 0.00041 20.4 0.1 0.00063 19.8 0.1 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 EKX35556.1 - 0.00053 20.7 0.0 0.00066 20.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EKX35556.1 - 0.0055 16.8 0.0 0.0095 16.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EKX35556.1 - 0.041 13.3 0.0 0.085 12.3 0.0 1.4 1 1 0 1 1 1 0 Putative acetyl-transferase CaiF_GrlA PF07180.11 EKX35556.1 - 0.12 12.3 0.2 0.22 11.5 0.2 1.4 1 0 0 1 1 1 0 CaiF/GrlA transcriptional regulator RBD PF02196.15 EKX35556.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Raf-like Ras-binding domain DUF4692 PF15763.5 EKX35557.1 - 0.097 13.1 2.8 0.15 12.6 2.8 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Ank_5 PF13857.6 EKX35560.1 - 5.1e-13 49.0 0.4 9.7e-08 32.1 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX35560.1 - 1.7e-11 44.4 0.1 2.1e-11 44.1 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX35560.1 - 1.1e-10 42.0 0.0 1.2e-10 41.8 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX35560.1 - 4.1e-10 39.0 0.1 8.7e-05 22.6 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EKX35560.1 - 1.7e-05 25.0 0.0 0.0064 16.9 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Pkinase PF00069.25 EKX35561.1 - 8.7e-09 35.1 0.2 1.5e-08 34.4 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX35561.1 - 0.00024 20.5 0.3 0.00046 19.5 0.3 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase zf-RING_2 PF13639.6 EKX35563.1 - 5.5e-11 42.6 12.7 1.1e-10 41.7 12.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX35563.1 - 2.4e-10 40.1 11.0 5.5e-10 38.9 11.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EKX35563.1 - 3.7e-10 39.5 9.3 6.1e-10 38.8 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX35563.1 - 6e-09 35.8 9.3 1.3e-08 34.7 9.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EKX35563.1 - 7.5e-08 32.2 9.5 1.3e-07 31.5 9.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EKX35563.1 - 8.2e-08 32.4 7.9 2.3e-07 31.0 7.9 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EKX35563.1 - 1.7e-07 31.0 10.3 3.4e-07 30.0 10.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EKX35563.1 - 4.8e-07 29.8 9.5 9.7e-07 28.9 9.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EKX35563.1 - 7.7e-06 25.7 9.9 1.5e-05 24.8 9.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DZR PF12773.7 EKX35563.1 - 0.019 15.0 3.8 0.037 14.1 3.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-Nse PF11789.8 EKX35563.1 - 0.038 13.8 5.2 0.087 12.7 5.2 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 EKX35563.1 - 0.042 13.9 7.1 0.19 11.8 7.1 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 EKX35563.1 - 0.13 12.4 6.9 0.31 11.2 6.9 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 TFIIA PF03153.13 EKX35563.1 - 0.18 11.8 11.4 0.22 11.5 11.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-RING_6 PF14835.6 EKX35563.1 - 0.24 11.3 5.9 0.58 10.1 5.9 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 EKX35563.1 - 0.53 10.1 9.3 1.9 8.4 9.3 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain UMP1 PF05348.11 EKX35563.1 - 0.57 10.4 6.4 0.86 9.8 5.5 1.8 2 0 0 2 2 2 0 Proteasome maturation factor UMP1 zinc-ribbons_6 PF07191.12 EKX35563.1 - 0.7 9.9 5.7 1.5 8.8 5.7 1.5 1 0 0 1 1 1 0 zinc-ribbons PhnA_Zn_Ribbon PF08274.12 EKX35563.1 - 0.73 9.8 3.5 9 6.3 1.5 2.5 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Zn_ribbon_17 PF17120.5 EKX35563.1 - 0.75 9.5 8.0 1.6 8.4 8.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF3810 PF12725.7 EKX35563.1 - 2.9 7.2 5.5 4.9 6.4 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) zf-P11 PF03854.14 EKX35563.1 - 8.8 6.1 8.7 11 5.8 3.2 2.3 1 1 1 2 2 2 0 P-11 zinc finger NTP_transf_2 PF01909.23 EKX35564.1 - 7.9e-06 26.1 0.0 2.2e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 EKX35564.1 - 0.00043 20.4 0.1 0.014 15.5 0.0 2.8 2 0 0 2 2 2 1 Cid1 family poly A polymerase Polbeta PF18765.1 EKX35564.1 - 0.062 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Baculo_PEP_C PF04513.12 EKX35565.1 - 0.047 13.7 1.9 0.21 11.6 2.0 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.6 EKX35565.1 - 0.049 14.0 3.2 0.074 13.5 1.3 2.2 2 0 0 2 2 2 0 Snapin/Pallidin Mito_carr PF00153.27 EKX35566.1 - 2.4e-15 56.2 0.2 2.2e-08 33.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein ubiquitin PF00240.23 EKX35567.1 - 1.1e-36 124.5 0.5 8.3e-19 67.1 0.1 2.1 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 EKX35567.1 - 8.1e-15 54.4 0.4 2e-07 30.8 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EKX35567.1 - 1.4e-08 34.5 0.1 5.4e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain UN_NPL4 PF11543.8 EKX35567.1 - 5.7e-05 23.5 0.1 0.12 12.9 0.0 2.2 2 0 0 2 2 2 2 Nuclear pore localisation protein NPL4 Ubiquitin_4 PF18036.1 EKX35567.1 - 0.00081 19.4 0.2 2 8.5 0.1 2.7 2 2 1 3 3 3 2 Ubiquitin-like domain Ubiquitin_2 PF14560.6 EKX35567.1 - 0.0013 19.1 1.0 1.6 9.2 0.0 3.1 2 2 0 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EKX35567.1 - 0.0049 17.0 0.0 2.8 8.1 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EKX35567.1 - 0.011 16.3 0.0 0.079 13.5 0.0 2.0 1 1 1 2 2 2 0 DUF2407 ubiquitin-like domain Flagellin_IN PF07196.13 EKX35567.1 - 0.055 13.7 0.7 12 6.2 0.1 2.4 2 0 0 2 2 2 0 Flagellin hook IN motif Ubiquitin_5 PF18037.1 EKX35567.1 - 0.081 13.3 0.0 0.33 11.3 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-like domain DUF4181 PF13789.6 EKX35568.1 - 1.5 9.1 5.3 0.95 9.8 2.5 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4181) LysM PF01476.20 EKX35569.1 - 0.0027 17.8 0.0 0.0041 17.2 0.0 1.3 1 0 0 1 1 1 1 LysM domain Mito_carr PF00153.27 EKX35570.1 - 2.9e-07 30.3 0.0 0.0034 17.3 0.0 2.7 1 1 1 2 2 2 2 Mitochondrial carrier protein Ank_5 PF13857.6 EKX35570.1 - 0.11 12.8 0.1 0.23 11.8 0.1 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) FH2 PF02181.23 EKX35570.1 - 0.14 11.2 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain Bundlin PF05307.11 EKX35570.1 - 0.19 11.6 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Bundlin LRR_8 PF13855.6 EKX35571.1 - 3.5e-44 148.4 48.0 2.7e-09 36.7 2.8 7.4 4 1 4 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 EKX35571.1 - 7.8e-41 137.4 45.4 1.2e-06 28.7 0.9 9.3 9 0 0 9 9 9 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX35571.1 - 9.6e-06 25.2 22.1 0.13 11.7 0.5 5.5 1 1 6 7 7 7 6 Leucine-rich repeat LRR_1 PF00560.33 EKX35571.1 - 0.00018 21.6 50.6 3.3 8.6 0.3 14.0 13 3 0 13 13 13 2 Leucine Rich Repeat LRR_5 PF13306.6 EKX35571.1 - 0.0014 18.6 5.8 1.8 8.5 0.1 4.0 2 1 2 5 5 5 3 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 EKX35571.1 - 0.0031 17.4 44.4 3.5 7.9 0.0 11.7 13 0 0 13 13 13 4 Leucine Rich repeat Raftlin PF15250.6 EKX35571.1 - 0.22 10.3 0.0 0.31 9.8 0.0 1.1 1 0 0 1 1 1 0 Raftlin CSTF_C PF14304.6 EKX35571.1 - 0.98 9.1 2.8 26 4.5 0.0 3.5 3 0 0 3 3 3 0 Transcription termination and cleavage factor C-terminal LRR_8 PF13855.6 EKX35572.1 - 5.9e-19 67.6 33.2 2.9e-08 33.4 5.7 3.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EKX35572.1 - 5.3e-12 45.8 21.4 0.00024 21.4 3.2 3.8 1 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX35572.1 - 4.6e-05 23.0 2.7 0.029 13.9 0.5 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 EKX35572.1 - 0.24 12.1 23.8 11 7.1 0.2 6.0 4 1 1 5 5 5 0 Leucine Rich Repeat DASH_Dam1 PF08653.10 EKX35572.1 - 2.1 8.2 5.3 16 5.4 0.2 3.3 3 1 1 4 4 4 0 DASH complex subunit Dam1 Fz PF01392.22 EKX35573.1 - 1e-05 26.1 2.0 1.8e-05 25.3 2.0 1.5 1 0 0 1 1 1 1 Fz domain PA14 PF07691.12 EKX35574.1 - 3.5e-09 36.6 0.1 1.2e-05 25.2 0.0 2.5 2 0 0 2 2 2 2 PA14 domain CBM_6 PF03422.15 EKX35574.1 - 0.028 14.7 0.4 0.58 10.5 0.0 2.7 2 1 0 2 2 2 0 Carbohydrate binding module (family 6) Amino_oxidase PF01593.24 EKX35575.1 - 8.2e-25 88.0 0.2 7.5e-11 42.0 0.0 3.0 1 1 2 3 3 3 3 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EKX35575.1 - 1.9e-06 28.0 0.1 3.6e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EKX35575.1 - 0.016 14.3 0.3 0.033 13.2 0.3 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 EKX35575.1 - 0.051 12.7 0.1 0.065 12.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 EKX35575.1 - 0.074 12.3 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 EKX35575.1 - 0.13 11.6 0.1 0.17 11.2 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 EKX35575.1 - 0.15 11.6 2.7 1.1 8.7 2.7 2.1 2 1 0 2 2 2 0 FAD dependent oxidoreductase Sulf_transp PF04143.14 EKX35576.1 - 9.1e-40 137.1 20.7 1.1e-39 136.8 20.7 1.0 1 0 0 1 1 1 1 Sulphur transport Sulf_transp PF04143.14 EKX35577.1 - 1.3e-27 97.2 26.3 1.8e-14 54.1 11.1 2.5 1 1 1 2 2 2 2 Sulphur transport DUF3551 PF12071.8 EKX35578.1 - 0.018 15.1 0.0 0.028 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3551) Collagen PF01391.18 EKX35579.1 - 1.7e-15 56.5 59.6 6.6e-09 35.4 27.9 2.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Beta_helix PF13229.6 EKX35580.1 - 2.1e-47 160.9 58.1 1.4e-20 73.7 4.8 5.3 1 1 4 5 5 5 5 Right handed beta helix region NosD PF05048.13 EKX35580.1 - 2.3e-34 118.7 27.6 4.5e-11 42.5 1.2 5.2 1 1 4 5 5 5 5 Periplasmic copper-binding protein (NosD) Disaggr_assoc PF08480.10 EKX35580.1 - 1.8 8.4 7.3 3.3 7.6 0.5 4.0 2 1 1 3 3 3 0 Disaggregatase related zf-CSL PF05207.13 EKX35581.1 - 4.8e-22 77.5 0.8 5.7e-22 77.2 0.8 1.1 1 0 0 1 1 1 1 CSL zinc finger zf-RING_4 PF14570.6 EKX35581.1 - 0.0086 15.8 0.4 0.014 15.1 0.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.10 EKX35581.1 - 0.043 14.0 0.2 0.065 13.4 0.2 1.4 1 0 0 1 1 1 0 Zinc ribbon domain DUF563 PF04577.14 EKX35582.1 - 4.7e-25 88.9 0.1 9.2e-25 88.0 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF563) LRR_4 PF12799.7 EKX35583.1 - 0.0002 21.7 0.0 0.00087 19.6 0.0 2.2 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX35583.1 - 0.0058 16.4 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_9 PF14580.6 EKX35583.1 - 0.02 14.4 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat RRN3 PF05327.11 EKX35583.1 - 0.62 8.5 6.0 1.1 7.7 6.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 fn2 PF00040.19 EKX35584.1 - 0.01 16.1 4.7 0.032 14.5 4.7 1.9 1 1 0 1 1 1 1 Fibronectin type II domain UL42 PF17638.2 EKX35584.1 - 0.024 14.6 0.2 0.054 13.5 0.2 1.5 1 0 0 1 1 1 0 HCMV UL42 cNMP_binding PF00027.29 EKX35586.1 - 3e-08 33.6 0.5 3.4e-07 30.2 0.1 2.2 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Dpy-30 PF05186.13 EKX35586.1 - 2.1e-05 24.1 0.2 4.6e-05 23.0 0.2 1.5 1 0 0 1 1 1 1 Dpy-30 motif Cupin_2 PF07883.11 EKX35586.1 - 0.17 11.6 0.5 0.35 10.6 0.5 1.4 1 0 0 1 1 1 0 Cupin domain Glutaredoxin PF00462.24 EKX35586.1 - 0.17 12.1 0.2 33 4.8 0.1 3.2 2 1 1 3 3 3 0 Glutaredoxin SAM_KSR1 PF13543.6 EKX35586.1 - 1 9.5 3.9 0.32 11.1 0.5 1.9 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 Ank_4 PF13637.6 EKX35587.1 - 1.3e-20 73.5 7.7 6.6e-08 32.9 0.1 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX35587.1 - 2.1e-19 69.8 0.8 6.9e-09 36.2 0.2 2.3 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX35587.1 - 1.1e-16 59.2 3.2 1.7e-05 24.8 0.0 4.5 4 1 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EKX35587.1 - 2.4e-15 56.2 6.0 3.4e-08 33.6 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EKX35587.1 - 1.3e-13 50.9 4.1 9.8e-07 28.9 0.2 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) ERAP1_C PF11838.8 EKX35587.1 - 0.025 14.1 0.2 0.03 13.9 0.2 1.1 1 0 0 1 1 1 0 ERAP1-like C-terminal domain TPR_20 PF14561.6 EKX35587.1 - 0.042 14.2 0.6 0.1 12.9 0.3 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1843 PF08898.10 EKX35587.1 - 0.056 13.9 0.4 3.1 8.4 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1843) Ank_5 PF13857.6 EKX35588.1 - 3.8e-22 78.0 0.2 4.8e-08 33.1 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX35588.1 - 1.9e-17 63.6 0.0 6e-17 62.0 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX35588.1 - 4.8e-17 61.6 0.0 7.3e-06 26.2 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EKX35588.1 - 2.3e-16 59.9 0.0 5.7e-06 26.8 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX35588.1 - 8.9e-12 44.1 0.0 0.00013 22.1 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Aldo_ket_red PF00248.21 EKX35589.1 - 0.021 14.1 1.3 0.052 12.7 0.3 2.0 2 0 0 2 2 2 0 Aldo/keto reductase family AAA_22 PF13401.6 EKX35590.1 - 0.0072 16.6 0.0 0.027 14.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain DUF1090 PF06476.12 EKX35590.1 - 0.32 11.1 45.5 0.36 10.9 3.6 6.8 1 1 6 7 7 7 0 Protein of unknown function (DUF1090) AAA_25 PF13481.6 EKX35592.1 - 2e-06 27.5 0.1 5.6e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EKX35592.1 - 5.8e-05 23.0 14.2 0.0027 17.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EKX35592.1 - 0.014 15.4 0.1 0.014 15.4 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EKX35592.1 - 0.044 14.1 1.1 0.13 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EKX35592.1 - 0.079 13.3 0.0 0.33 11.3 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 EKX35592.1 - 0.089 12.3 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 EKX35592.1 - 0.12 12.8 0.0 0.66 10.4 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EKX35592.1 - 0.18 12.2 0.1 0.69 10.2 0.1 2.0 1 0 0 1 1 1 0 AAA domain NUDE_C PF04880.13 EKX35592.1 - 0.55 10.7 19.3 1.5 9.3 19.3 1.7 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region FliD_C PF07195.12 EKX35592.1 - 0.97 8.8 7.6 2.3 7.6 7.6 1.5 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Form_Nir_trans PF01226.17 EKX35594.1 - 1.4e-64 217.7 18.3 1.7e-64 217.4 18.3 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter EF-hand_1 PF00036.32 EKX35594.1 - 3.1e-13 48.2 2.0 1.9e-05 23.9 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX35594.1 - 2e-12 47.3 0.4 4.2e-12 46.3 0.3 1.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX35594.1 - 3.9e-12 45.1 1.9 7.7e-06 25.4 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EKX35594.1 - 2.1e-09 37.1 2.2 3e-05 23.8 0.4 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX35594.1 - 7.7e-06 25.2 1.5 0.0012 18.3 0.2 2.4 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 EKX35594.1 - 8.2e-06 25.7 0.2 2.7e-05 24.0 0.2 1.8 1 1 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EKX35594.1 - 0.16 12.4 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain Sugar_tr PF00083.24 EKX35595.1 - 6.9e-49 166.9 14.6 4.2e-26 91.8 4.2 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 EKX35595.1 - 5.9e-13 48.5 9.7 5.9e-13 48.5 9.7 2.8 2 2 0 2 2 2 1 Major Facilitator Superfamily Pro_isomerase PF00160.21 EKX35596.1 - 9e-45 152.8 0.0 2e-44 151.7 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4337 PF14235.6 EKX35596.1 - 2.9 8.0 4.8 5.3 7.1 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Phage_B PF02304.15 EKX35596.1 - 3.2 8.2 4.6 4.5 7.7 0.3 2.5 2 1 1 3 3 3 0 Scaffold protein B Lipase_3 PF01764.25 EKX35599.1 - 2.2e-10 40.6 0.0 1e-09 38.4 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) Sas10 PF09368.10 EKX35600.1 - 4.5e-11 43.1 5.6 4.5e-11 43.1 5.6 3.5 3 0 0 3 3 3 1 Sas10 C-terminal domain Agenet PF05641.12 EKX35601.1 - 6.2e-08 33.0 11.0 0.013 16.0 0.7 3.8 4 0 0 4 4 4 3 Agenet domain Tudor-knot PF11717.8 EKX35601.1 - 1.1e-05 25.2 6.9 0.00073 19.4 0.6 3.2 3 0 0 3 3 3 2 RNA binding activity-knot of a chromodomain TUDOR PF00567.24 EKX35601.1 - 6.7e-05 22.9 4.9 0.1 12.6 0.2 3.3 3 0 0 3 3 3 2 Tudor domain MBT PF02820.18 EKX35601.1 - 0.0017 18.7 1.4 1.4 9.3 0.1 2.4 2 0 0 2 2 2 2 mbt repeat Phage_base_V PF04717.12 EKX35601.1 - 0.0077 16.1 1.6 0.47 10.4 0.1 2.6 2 0 0 2 2 2 1 Type VI secretion system, phage-baseplate injector SAWADEE PF16719.5 EKX35601.1 - 0.012 15.6 1.1 2.3 8.2 0.2 2.4 1 1 1 2 2 2 0 SAWADEE domain Tudor_2 PF18104.1 EKX35601.1 - 0.12 12.1 1.3 13 5.6 0.2 2.5 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain SpoIIIAH PF12685.7 EKX35604.1 - 0.052 13.4 2.2 0.13 12.1 2.2 1.6 1 0 0 1 1 1 0 SpoIIIAH-like protein SAC3_GANP PF03399.16 EKX35606.1 - 9.3e-18 64.6 0.0 1.4e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP family IL33 PF15095.6 EKX35606.1 - 0.028 13.9 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 Interleukin 33 LRR_8 PF13855.6 EKX35608.1 - 4.1e-18 64.9 13.8 5.2e-12 45.4 5.1 1.8 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EKX35608.1 - 4.3e-09 36.5 10.1 3.6e-07 30.4 3.2 1.9 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX35608.1 - 0.00027 21.1 3.1 1.2 10.0 0.0 3.1 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_5 PF13306.6 EKX35608.1 - 0.00063 19.7 0.1 0.00077 19.4 0.1 1.1 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 EKX35608.1 - 0.074 12.6 0.1 0.14 11.7 0.1 1.3 1 1 0 1 1 1 0 Leucine-rich repeat CopC PF04234.12 EKX35609.1 - 0.0001 23.3 0.0 58 4.8 0.0 7.0 10 0 0 10 10 10 1 CopC domain TIG PF01833.24 EKX35609.1 - 0.0022 18.0 2.9 1.3 9.2 0.1 5.2 3 0 0 3 3 3 2 IPT/TIG domain MIF4G PF02854.19 EKX35610.1 - 2e-34 119.1 0.4 2e-34 119.1 0.4 2.4 4 0 0 4 4 4 1 MIF4G domain MA3 PF02847.17 EKX35610.1 - 1.1e-13 51.2 0.2 4.4e-13 49.2 0.1 2.1 2 0 0 2 2 2 1 MA3 domain PAM2 PF07145.15 EKX35610.1 - 0.0039 16.8 14.6 0.041 13.6 5.1 3.5 2 1 1 3 3 3 3 Ataxin-2 C-terminal region LRR_8 PF13855.6 EKX35611.1 - 1.3e-20 72.9 36.6 3.8e-06 26.6 2.1 5.4 2 1 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 EKX35611.1 - 1.1e-15 57.5 26.7 3e-06 27.5 1.0 5.5 2 1 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX35611.1 - 4.2e-05 23.1 4.9 0.013 15.0 0.3 3.1 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 EKX35611.1 - 0.0026 18.1 30.1 13 6.8 0.0 9.1 8 1 1 9 9 9 2 Leucine Rich Repeat LRR_6 PF13516.6 EKX35611.1 - 0.003 17.5 14.1 2.4 8.4 0.2 7.0 7 0 0 7 7 7 2 Leucine Rich repeat SCRG1 PF15224.6 EKX35611.1 - 0.12 12.5 0.4 4.8 7.4 0.1 2.8 2 1 0 2 2 2 0 Scrapie-responsive protein 1 Pigment_DH PF06324.11 EKX35611.1 - 1.4 9.2 8.4 1.5 9.1 0.2 3.8 4 0 0 4 4 4 0 Pigment-dispersing hormone (PDH) YABBY PF04690.13 EKX35613.1 - 4.6e-08 33.8 2.5 1.6e-07 32.0 2.5 1.9 1 1 0 1 1 1 1 YABBY protein Ccdc124 PF06244.12 EKX35613.1 - 6.3e-05 23.5 0.3 6.3e-05 23.5 0.3 3.2 4 0 0 4 4 4 1 Coiled-coil domain-containing protein 124 /Oxs1 GCIP PF13324.6 EKX35613.1 - 9e-05 22.2 1.8 0.00014 21.6 1.8 1.3 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting HMG_box_2 PF09011.10 EKX35613.1 - 0.0023 18.5 0.2 0.0052 17.4 0.2 1.6 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 EKX35613.1 - 0.0027 18.1 0.3 0.006 17.0 0.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box DUF913 PF06025.12 EKX35613.1 - 0.84 8.5 5.3 1.1 8.1 1.8 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) MCM_bind PF09739.9 EKX35613.1 - 4.9 5.5 6.2 2.6 6.4 0.2 2.0 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor ABC_tran PF00005.27 EKX35614.1 - 5.5e-47 159.7 2.6 2e-25 89.9 0.5 4.3 2 2 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EKX35614.1 - 8.5e-13 48.2 2.6 0.00013 21.5 0.3 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EKX35614.1 - 1.4e-12 48.1 0.6 0.0044 16.9 0.0 4.4 2 2 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EKX35614.1 - 7.9e-07 28.7 0.0 0.052 13.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 EKX35614.1 - 1.9e-06 27.8 1.8 0.073 12.8 0.0 3.7 3 1 2 5 5 5 2 AAA ATPase domain MMR_HSR1 PF01926.23 EKX35614.1 - 7.8e-06 25.9 0.0 0.14 12.2 0.0 3.2 3 0 0 3 3 2 2 50S ribosome-binding GTPase DUF815 PF05673.13 EKX35614.1 - 1.4e-05 24.4 0.0 0.0064 15.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 EKX35614.1 - 1.8e-05 25.0 0.0 0.11 12.8 0.0 3.2 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EKX35614.1 - 2.4e-05 24.3 0.0 0.15 11.9 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase 4HB PF17947.1 EKX35614.1 - 3.2e-05 23.9 0.0 0.00029 20.8 0.0 2.7 2 0 0 2 2 1 1 Four helical bundle domain AAA_28 PF13521.6 EKX35614.1 - 3.2e-05 24.2 0.0 0.033 14.5 0.1 2.9 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 EKX35614.1 - 3.6e-05 24.2 0.5 0.88 10.0 0.0 3.8 5 1 0 5 5 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX35614.1 - 8.6e-05 23.0 0.0 0.18 12.2 0.0 3.1 3 0 0 3 3 2 1 AAA ATPase domain Chromo PF00385.24 EKX35614.1 - 0.00013 21.8 2.9 0.00038 20.3 2.9 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_7 PF12775.7 EKX35614.1 - 0.00017 21.1 0.0 0.18 11.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 EKX35614.1 - 0.0002 21.5 0.0 0.97 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EKX35614.1 - 0.00038 20.8 0.0 0.53 10.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase ATPase_2 PF01637.18 EKX35614.1 - 0.00047 20.1 0.9 3.7 7.4 0.0 3.6 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea MeaB PF03308.16 EKX35614.1 - 0.00059 18.9 0.1 0.54 9.2 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 EKX35614.1 - 0.0008 19.5 0.3 0.076 13.1 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_18 PF13238.6 EKX35614.1 - 0.0019 18.7 0.1 2.6 8.6 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_27 PF13514.6 EKX35614.1 - 0.0048 16.5 0.1 1.1 8.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EKX35614.1 - 0.005 17.4 21.9 0.017 15.6 0.0 4.0 4 1 0 4 4 3 1 AAA domain AAA_24 PF13479.6 EKX35614.1 - 0.0063 16.3 0.0 0.68 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 EKX35614.1 - 0.0063 16.7 0.0 1.3 9.3 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 EKX35614.1 - 0.0084 15.3 0.0 2 7.5 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_14 PF13173.6 EKX35614.1 - 0.0087 16.1 0.0 3.7 7.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EKX35614.1 - 0.0098 15.8 0.0 1.7 8.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Rad17 PF03215.15 EKX35614.1 - 0.01 15.8 0.0 3.8 7.4 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain G-alpha PF00503.20 EKX35614.1 - 0.014 14.6 0.5 2.1 7.4 0.1 2.8 3 0 0 3 3 3 0 G-protein alpha subunit TniB PF05621.11 EKX35614.1 - 0.014 14.8 0.1 0.22 10.9 0.0 2.7 3 0 0 3 3 2 0 Bacterial TniB protein Septin PF00735.18 EKX35614.1 - 0.035 13.4 0.0 5.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Septin AAA_30 PF13604.6 EKX35614.1 - 0.035 13.8 4.6 2.3 7.9 0.0 3.8 5 0 0 5 5 3 0 AAA domain ATP-synt_ab PF00006.25 EKX35614.1 - 0.039 13.6 0.0 0.49 10.0 0.0 2.6 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain HEAT_2 PF13646.6 EKX35614.1 - 0.042 14.2 5.7 3.9 7.9 0.1 4.8 3 1 0 4 4 4 0 HEAT repeats DUF87 PF01935.17 EKX35614.1 - 0.051 13.6 4.7 4.6 7.3 0.1 3.8 4 0 0 4 4 3 0 Helicase HerA, central domain Zeta_toxin PF06414.12 EKX35614.1 - 0.058 12.7 0.9 3.8 6.7 0.1 3.0 2 1 1 3 3 3 0 Zeta toxin HEAT PF02985.22 EKX35614.1 - 0.066 13.5 1.0 12 6.4 0.0 4.0 4 0 0 4 4 3 0 HEAT repeat Vac14_Fab1_bd PF12755.7 EKX35614.1 - 0.074 13.7 0.0 1.9 9.2 0.0 2.7 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region PRK PF00485.18 EKX35614.1 - 0.1 12.3 0.2 4.3 7.0 0.0 2.7 2 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family FeoB_N PF02421.18 EKX35614.1 - 0.12 11.8 0.1 9 5.8 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF3419 PF11899.8 EKX35615.1 - 3e-73 247.2 0.3 4e-73 246.8 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 EKX35615.1 - 4e-13 49.5 0.0 3.3e-12 46.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX35615.1 - 1.5e-11 44.9 0.0 7.5e-09 36.2 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 EKX35615.1 - 3.4e-11 43.7 0.1 1.2e-08 35.5 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX35615.1 - 8.1e-10 39.2 0.1 1.9e-07 31.6 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX35615.1 - 2.4e-09 37.2 0.1 2.2e-07 30.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX35615.1 - 5.7e-09 35.7 0.0 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 EKX35615.1 - 0.00049 19.7 0.4 0.0047 16.5 0.0 2.3 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Abhydrolase_3 PF07859.13 EKX35616.1 - 3.6e-22 79.3 0.1 7.4e-11 42.3 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold DEC-1_N PF04625.13 EKX35617.1 - 0.056 12.5 6.0 0.086 11.8 6.0 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region PRC2_HTH_1 PF18118.1 EKX35618.1 - 0.1 13.4 0.3 0.23 12.3 0.3 1.5 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain TMEM154 PF15102.6 EKX35618.1 - 0.85 9.5 4.4 1.6 8.6 4.4 1.4 1 0 0 1 1 1 0 TMEM154 protein family LRR_4 PF12799.7 EKX35620.1 - 9.3e-07 29.1 8.3 0.0044 17.4 0.0 3.6 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX35620.1 - 0.00043 20.0 9.7 0.0052 16.5 0.1 3.4 2 1 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 EKX35620.1 - 0.091 12.3 0.5 0.41 10.1 0.4 1.8 1 1 1 2 2 2 0 Leucine-rich repeat Mtp PF03821.16 EKX35620.1 - 0.71 9.4 2.7 9.5 5.7 1.0 2.2 1 1 1 2 2 2 0 Golgi 4-transmembrane spanning transporter LRR_6 PF13516.6 EKX35620.1 - 0.72 10.1 9.1 14 6.1 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 EKX35620.1 - 4 8.4 9.9 35 5.5 0.6 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat Pkinase PF00069.25 EKX35621.1 - 4.6e-49 167.1 0.3 6.2e-49 166.7 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX35621.1 - 5.5e-37 127.4 0.3 3.4e-36 124.9 0.3 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase NFRKB_winged PF14465.6 EKX35621.1 - 0.023 14.9 0.3 0.18 12.0 0.0 2.3 2 1 1 3 3 3 0 NFRKB Winged Helix-like CLASP_N PF12348.8 EKX35622.1 - 2.4e-05 24.0 0.2 3.9e-05 23.3 0.2 1.3 1 0 0 1 1 1 1 CLASP N terminal Urease_gamma PF00547.18 EKX35622.1 - 0.00011 22.5 0.6 0.0035 17.6 0.0 2.7 2 1 1 3 3 3 1 Urease, gamma subunit HEAT PF02985.22 EKX35622.1 - 0.0021 18.1 0.2 3.9 8.0 0.0 3.9 4 0 0 4 4 4 1 HEAT repeat ParcG PF10274.9 EKX35622.1 - 0.0077 16.4 0.0 3.6 7.7 0.0 2.4 1 1 0 2 2 2 2 Parkin co-regulated protein HEAT_EZ PF13513.6 EKX35622.1 - 0.017 15.6 0.1 7.1 7.3 0.0 3.0 3 0 0 3 3 3 0 HEAT-like repeat Phage_TAC_7 PF10109.9 EKX35622.1 - 0.097 12.8 0.3 1 9.5 0.0 2.7 3 1 0 3 3 3 0 Phage tail assembly chaperone proteins, E, or 41 or 14 Urb2 PF10441.9 EKX35622.1 - 0.11 12.5 0.2 0.94 9.4 0.1 2.1 1 1 0 2 2 2 0 Urb2/Npa2 family V-ATPase_H_C PF11698.8 EKX35622.1 - 0.12 12.5 0.8 6.4 6.9 0.1 2.4 2 1 0 2 2 2 0 V-ATPase subunit H ABC_tran PF00005.27 EKX35623.1 - 2.2e-46 157.7 1.6 7.4e-24 84.8 0.4 4.3 2 2 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EKX35623.1 - 1.7e-13 50.6 1.6 6.2e-05 22.5 0.2 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EKX35623.1 - 3.4e-13 50.1 2.5 0.0089 15.9 0.0 4.5 2 2 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EKX35623.1 - 1.8e-07 30.8 0.1 0.024 14.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EKX35623.1 - 4.2e-07 30.0 0.1 0.026 14.6 0.2 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 EKX35623.1 - 8e-07 29.1 0.3 0.04 13.6 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain Chromo PF00385.24 EKX35623.1 - 8.9e-06 25.5 3.4 2.1e-05 24.3 3.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_28 PF13521.6 EKX35623.1 - 9.2e-06 26.0 0.0 0.055 13.7 0.1 2.7 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 EKX35623.1 - 1.1e-05 24.7 0.0 0.0062 15.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 EKX35623.1 - 1.3e-05 25.2 0.3 0.16 11.9 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase AAA_22 PF13401.6 EKX35623.1 - 2.1e-05 24.8 0.0 0.11 12.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EKX35623.1 - 4.7e-05 23.8 0.0 0.16 12.3 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 EKX35623.1 - 5.7e-05 23.7 19.6 0.00095 19.7 0.0 4.2 4 1 0 4 4 4 1 AAA domain AAA PF00004.29 EKX35623.1 - 6.8e-05 23.3 0.0 0.99 9.8 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EKX35623.1 - 0.00024 21.3 0.0 1 9.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EKX35623.1 - 0.00041 20.7 0.0 0.52 10.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 EKX35623.1 - 0.00065 19.3 0.0 0.56 9.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 EKX35623.1 - 0.00083 19.9 0.0 2.2 8.8 0.0 3.4 2 1 0 2 2 2 1 AAA domain MeaB PF03308.16 EKX35623.1 - 0.00089 18.3 0.1 0.55 9.2 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_14 PF13173.6 EKX35623.1 - 0.0019 18.2 0.0 1.9 8.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 EKX35623.1 - 0.0019 18.3 0.9 0.037 14.1 0.1 2.7 3 0 0 3 3 2 1 Dynamin family Roc PF08477.13 EKX35623.1 - 0.0024 18.1 0.0 1 9.6 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_27 PF13514.6 EKX35623.1 - 0.0024 17.5 0.0 1.5 8.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EKX35623.1 - 0.0025 17.6 0.1 0.41 10.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EKX35623.1 - 0.0074 16.2 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Rad17 PF03215.15 EKX35623.1 - 0.0081 16.1 0.1 3.4 7.6 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_30 PF13604.6 EKX35623.1 - 0.0083 15.9 1.7 5.4 6.7 0.0 3.6 4 0 0 4 4 4 0 AAA domain ATP-synt_ab PF00006.25 EKX35623.1 - 0.011 15.5 0.0 0.24 11.0 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain G-alpha PF00503.20 EKX35623.1 - 0.012 14.8 0.1 1.5 7.9 0.2 2.3 2 0 0 2 2 2 0 G-protein alpha subunit DUF87 PF01935.17 EKX35623.1 - 0.017 15.2 3.0 2.3 8.3 0.0 3.4 4 0 0 4 4 2 0 Helicase HerA, central domain ATPase_2 PF01637.18 EKX35623.1 - 0.017 15.0 0.8 1.9 8.4 0.0 2.7 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EKX35623.1 - 0.025 13.7 0.5 1.9 7.6 0.0 2.6 2 1 0 2 2 2 0 NB-ARC domain PRK PF00485.18 EKX35623.1 - 0.034 13.9 0.0 1.6 8.4 0.0 2.6 2 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family TniB PF05621.11 EKX35623.1 - 0.039 13.4 0.0 1 8.7 0.0 2.8 2 0 0 2 2 2 0 Bacterial TniB protein Zeta_toxin PF06414.12 EKX35623.1 - 0.05 12.9 0.6 6.1 6.1 0.0 3.1 2 1 1 3 3 3 0 Zeta toxin PduV-EutP PF10662.9 EKX35623.1 - 0.068 12.9 0.0 12 5.6 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 EKX35623.1 - 0.11 12.1 0.1 6.6 6.2 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Arf PF00025.21 EKX35623.1 - 0.12 11.8 0.4 3.8 6.9 0.0 2.8 3 0 0 3 3 3 0 ADP-ribosylation factor family FKS1_dom1 PF14288.6 EKX35623.1 - 0.23 11.8 5.6 3.1 8.1 2.7 2.5 2 0 0 2 2 2 0 1,3-beta-glucan synthase subunit FKS1, domain-1 THOC7 PF05615.13 EKX35624.1 - 0.0088 16.3 4.2 0.019 15.2 4.2 1.7 1 0 0 1 1 1 1 Tho complex subunit 7 DUF4337 PF14235.6 EKX35624.1 - 0.17 12.0 1.2 0.38 10.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) BST2 PF16716.5 EKX35624.1 - 0.63 10.7 4.4 1.6 9.4 4.4 1.7 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 DUF2852 PF11014.8 EKX35624.1 - 1.3 9.2 5.1 6.2 7.0 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) Atg14 PF10186.9 EKX35624.1 - 1.8 7.6 12.1 0.17 10.9 6.7 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HIP1_clath_bdg PF16515.5 EKX35624.1 - 9.3 6.9 15.1 0.15 12.7 6.8 2.3 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PALP PF00291.25 EKX35625.1 - 2.1e-14 53.6 0.0 1.5e-07 31.2 0.1 2.7 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme Mu-like_Com PF10122.9 EKX35625.1 - 0.16 11.4 0.0 0.41 10.1 0.0 1.6 1 0 0 1 1 1 0 Mu-like prophage protein Com RNA_pol_L PF01193.24 EKX35626.1 - 1.3e-22 79.0 0.0 1.7e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_A_bac PF01000.26 EKX35626.1 - 8.9e-19 67.9 0.0 1.9e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain Fer4_7 PF12838.7 EKX35626.1 - 0.17 12.5 1.7 0.46 11.1 1.7 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain HA PF03457.14 EKX35627.1 - 1.1e-14 54.4 1.4 9.9e-11 41.8 0.4 2.6 2 1 0 2 2 2 2 Helicase associated domain SET PF00856.28 EKX35628.1 - 1.4e-08 35.3 0.1 0.00039 20.8 0.0 2.2 1 1 1 2 2 2 2 SET domain TIG PF01833.24 EKX35629.1 - 1.4e-06 28.3 13.2 0.00071 19.6 1.0 4.5 4 0 0 4 4 4 2 IPT/TIG domain EGF_CA PF07645.15 EKX35629.1 - 0.0085 16.3 3.4 0.0085 16.3 3.4 4.4 3 1 0 3 3 3 1 Calcium-binding EGF domain LRR_8 PF13855.6 EKX35630.1 - 2.9e-34 116.6 56.2 1.6e-07 30.9 0.4 6.4 2 1 6 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 EKX35630.1 - 3.7e-28 97.1 40.7 1.4e-05 25.3 1.1 7.0 6 1 1 7 7 7 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX35630.1 - 1.8e-09 37.4 19.9 8.5e-05 22.1 0.7 4.4 1 1 4 5 5 5 5 Leucine-rich repeat LRR_5 PF13306.6 EKX35630.1 - 9.2e-05 22.4 1.0 0.0069 16.3 0.2 2.5 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EKX35630.1 - 0.00038 20.6 32.4 7.1 7.6 1.5 10.3 10 1 1 11 11 11 2 Leucine Rich Repeat RsmF_methylt_CI PF17126.5 EKX35630.1 - 0.018 15.0 0.2 17 5.5 0.0 4.3 4 1 1 5 5 5 0 RsmF rRNA methyltransferase first C-terminal domain LRR_6 PF13516.6 EKX35630.1 - 0.73 10.0 30.5 0.81 9.9 0.4 7.1 8 0 0 8 8 8 0 Leucine Rich repeat Lung_7-TM_R PF06814.13 EKX35631.1 - 1.5e-49 168.8 10.2 1.8e-49 168.6 10.2 1.0 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 EKX35631.1 - 0.24 10.8 18.6 0.02 14.3 12.6 2.1 2 1 1 3 3 3 0 Rhodopsin-like GPCR transmembrane domain FixP_N PF14715.6 EKX35631.1 - 0.41 10.4 0.1 0.41 10.4 0.1 3.1 4 0 0 4 4 4 0 N-terminal domain of cytochrome oxidase-cbb3, FixP CBM_20 PF00686.19 EKX35634.1 - 1.1e-12 47.7 0.0 2.1e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain Mitofilin PF09731.9 EKX35634.1 - 0.89 8.3 54.7 1.1 8.0 54.7 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SRP-alpha_N PF04086.13 EKX35634.1 - 6.1 6.7 46.7 9.6 6.0 46.7 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Castor_Poll_mid PF06241.12 EKX35635.1 - 1.2e-39 134.5 0.1 6.8e-34 116.0 0.0 3.4 3 0 0 3 3 3 2 Castor and Pollux, part of voltage-gated ion channel TrkA_C PF02080.21 EKX35635.1 - 0.019 14.8 1.9 0.046 13.5 0.0 2.7 3 0 0 3 3 3 0 TrkA-C domain RII_binding_1 PF10522.9 EKX35635.1 - 1.9 8.9 4.5 1.7 9.1 2.1 2.3 2 0 0 2 2 2 0 RII binding domain Maf PF02545.14 EKX35636.1 - 2.3e-56 190.2 0.0 2.6e-56 190.0 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein Mad3_BUB1_II PF08171.11 EKX35636.1 - 0.14 12.4 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Mad3/BUB1 homology region 2 Pkinase PF00069.25 EKX35637.1 - 1.3e-70 237.8 0.0 1.5e-70 237.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX35637.1 - 6.1e-32 110.9 0.0 7.8e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX35637.1 - 0.00027 20.4 0.0 0.00041 19.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EKX35637.1 - 0.021 14.8 0.1 0.1 12.5 0.0 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EKX35637.1 - 0.21 10.5 0.0 0.29 10.0 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Asp_protease_2 PF13650.6 EKX35639.1 - 9.2e-07 29.4 0.0 2.1e-06 28.3 0.0 1.6 1 1 1 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 EKX35639.1 - 3.5e-06 27.5 0.1 6.6e-06 26.6 0.1 1.6 1 1 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 EKX35639.1 - 0.00083 19.1 0.0 0.0015 18.3 0.0 1.5 1 1 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2B PF12384.8 EKX35639.1 - 0.017 14.6 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Ty3 transposon peptidase RVP PF00077.20 EKX35639.1 - 0.018 15.4 0.0 0.033 14.5 0.0 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease Peptidase_A2E PF12382.8 EKX35639.1 - 0.054 13.5 0.0 0.069 13.2 0.0 1.1 1 0 0 1 1 1 0 Retrotransposon peptidase Asp_protease PF09668.10 EKX35639.1 - 0.086 12.6 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Arf PF00025.21 EKX35644.1 - 7e-44 149.3 0.0 1.1e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EKX35644.1 - 2.2e-09 37.1 0.0 4.7e-09 36.1 0.0 1.5 2 0 0 2 2 2 1 Ras family Roc PF08477.13 EKX35644.1 - 8.6e-09 35.7 0.0 1.8e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EKX35644.1 - 3e-06 26.8 1.4 3.6e-05 23.3 0.0 2.3 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EKX35644.1 - 3.4e-06 26.5 5.4 0.00026 20.3 0.0 3.1 2 1 1 3 3 3 2 G-protein alpha subunit MMR_HSR1 PF01926.23 EKX35644.1 - 6.3e-06 26.3 0.5 1.9e-05 24.7 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EKX35644.1 - 0.0032 16.9 0.2 0.0071 15.7 0.0 1.7 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EKX35644.1 - 0.0061 16.1 4.7 0.045 13.3 0.7 3.1 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Spore_III_AF PF09581.10 EKX35644.1 - 0.4 10.7 12.7 0.67 10.0 12.7 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) RR_TM4-6 PF06459.12 EKX35644.1 - 0.76 9.5 11.9 1.3 8.8 11.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vfa1 PF08432.10 EKX35644.1 - 0.83 10.0 12.5 1.5 9.2 12.5 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4407 PF14362.6 EKX35644.1 - 0.91 8.8 4.9 1.1 8.5 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GREB1 PF15782.5 EKX35644.1 - 1.2 6.2 3.4 1.4 5.9 3.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PEMT PF04191.13 EKX35645.1 - 1.8e-13 50.8 0.6 1.8e-13 50.8 0.6 1.6 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 EKX35645.1 - 8.7e-05 22.9 0.1 0.00015 22.1 0.1 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Ank_2 PF12796.7 EKX35646.1 - 1.6e-66 220.9 1.7 1.6e-09 38.2 0.0 8.1 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX35646.1 - 8.3e-63 208.0 0.0 9.8e-08 32.4 0.0 9.7 7 2 4 11 11 11 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX35646.1 - 1.1e-46 156.3 16.7 0.0028 17.9 0.2 15.0 5 5 10 15 15 15 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX35646.1 - 1.4e-38 126.5 0.1 0.39 11.4 0.0 15.5 16 0 0 16 16 16 9 Ankyrin repeat Ank PF00023.30 EKX35646.1 - 2.5e-27 94.1 7.5 0.27 11.7 0.0 14.0 15 0 0 15 15 15 5 Ankyrin repeat INT_SG_DDX_CT_C PF15300.6 EKX35646.1 - 0.0065 16.2 1.2 9.5 6.1 0.0 5.0 6 2 2 8 8 8 1 INTS6/SAGE1/DDX26B/CT45 C-terminus VCH_CASS14 PF18315.1 EKX35646.1 - 0.0079 16.2 1.1 33 4.6 0.0 4.3 3 1 1 4 4 4 0 Integron cassette protein VCH_CASS1 chain Chol_subst-bind PF09129.11 EKX35646.1 - 0.029 13.3 0.0 61 2.4 0.0 4.9 3 1 3 6 6 6 0 Cholesterol oxidase, substrate-binding CdAMP_rec PF06153.11 EKX35646.1 - 0.071 13.3 0.0 68 3.7 0.0 4.7 4 2 3 7 7 7 0 Cyclic-di-AMP receptor SPATA24 PF15175.6 EKX35646.1 - 0.096 12.6 0.2 21 4.9 0.0 3.2 2 1 0 3 3 3 0 Spermatogenesis-associated protein 24 Ins_beta PF03488.14 EKX35646.1 - 0.73 9.9 40.4 19 5.4 0.0 12.8 15 0 0 15 15 15 0 Nematode insulin-related peptide beta type DUF892 PF05974.12 EKX35646.1 - 5.1 7.1 6.9 66 3.5 0.0 5.7 6 5 2 8 8 8 0 Domain of unknown function (DUF892) SNF2_N PF00176.23 EKX35647.1 - 1.1e-26 93.5 0.2 1.5e-26 92.9 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Ank_2 PF12796.7 EKX35648.1 - 4.2e-41 139.4 2.1 1.2e-09 38.6 0.0 5.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX35648.1 - 4.1e-39 132.5 0.0 6.6e-08 32.9 0.0 6.6 6 1 0 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX35648.1 - 4e-26 90.7 7.4 0.055 13.8 0.0 8.2 4 2 4 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX35648.1 - 4.7e-23 78.8 0.2 0.026 15.0 0.0 8.9 9 0 0 9 9 9 6 Ankyrin repeat Ank PF00023.30 EKX35648.1 - 6e-17 61.3 3.6 2.7 8.6 0.0 8.5 9 0 0 9 9 9 4 Ankyrin repeat Chol_subst-bind PF09129.11 EKX35648.1 - 0.043 12.8 0.0 14 4.5 0.0 3.7 3 1 2 5 5 5 0 Cholesterol oxidase, substrate-binding DUF4265 PF14085.6 EKX35648.1 - 0.044 13.8 1.3 0.98 9.4 0.0 3.2 2 2 1 4 4 4 0 Domain of unknown function (DUF4265) Imm17 PF15562.6 EKX35648.1 - 0.1 12.5 0.0 1.9e+02 2.0 0.0 4.8 6 1 0 6 6 6 0 Immunity protein 17 Hva1_TUDOR PF11160.8 EKX35648.1 - 0.13 12.5 0.8 24 5.2 0.0 4.4 4 0 0 4 4 4 0 Hypervirulence associated proteins TUDOR domain Ins_beta PF03488.14 EKX35648.1 - 0.18 11.8 14.6 37 4.5 0.1 6.3 6 1 0 7 7 7 0 Nematode insulin-related peptide beta type VHS PF00790.19 EKX35648.1 - 0.3 10.9 1.6 51 3.7 0.0 3.8 5 0 0 5 5 5 0 VHS domain mRNA_cap_enzyme PF01331.19 EKX35651.1 - 0.044 13.6 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 mRNA capping enzyme, catalytic domain SPC25 PF06703.11 EKX35652.1 - 5.3 6.8 7.9 3.3 7.5 0.4 2.9 2 1 1 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Spc7_C2 PF15577.6 EKX35653.1 - 0.015 15.4 0.1 0.029 14.4 0.1 1.4 1 0 0 1 1 1 0 Spc7_C2 DUF2880 PF11082.8 EKX35653.1 - 0.053 13.8 0.0 0.089 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2880) Retrotran_gag_2 PF14223.6 EKX35654.1 - 0.0032 17.1 0.0 0.0043 16.7 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF3744 PF12558.8 EKX35654.1 - 0.16 12.8 0.0 0.24 12.2 0.0 1.4 1 0 0 1 1 1 0 ATP-binding cassette cobalt transporter DUF2201_N PF13203.6 EKX35655.1 - 0.069 12.7 3.7 0.12 11.9 3.7 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Toxin_12 PF07740.12 EKX35657.1 - 0.0051 17.5 0.6 0.0066 17.1 0.6 1.2 1 0 0 1 1 1 1 Ion channel inhibitory toxin Dickkopf_N PF04706.12 EKX35657.1 - 0.13 12.7 0.6 0.2 12.2 0.6 1.3 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Pkinase_Tyr PF07714.17 EKX35659.1 - 2.4e-38 131.9 0.0 2.6e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX35659.1 - 4.2e-15 55.8 0.0 4.7e-15 55.7 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX35660.1 - 3.2e-57 193.8 0.0 3.7e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX35660.1 - 1.3e-23 83.7 0.0 1.7e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 EKX35661.1 - 1.7e-50 167.9 32.9 1.6e-07 31.9 0.0 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.8 EKX35661.1 - 6.9e-09 34.9 14.1 2.3 6.7 0.2 6.9 1 1 6 7 7 7 6 Nucleoporin Nup120/160 Read-through PF16814.5 EKX35661.1 - 5e-07 29.7 1.4 27 4.5 0.0 6.5 1 1 6 7 7 7 0 Read-through domain WD40_like PF17005.5 EKX35661.1 - 5.8e-06 25.8 0.1 8.2 5.7 0.0 5.1 1 1 6 7 7 7 1 WD40-like domain Cytochrom_D1 PF02239.16 EKX35661.1 - 1.4e-05 23.8 6.9 0.061 11.8 0.4 3.5 1 1 3 4 4 4 4 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 EKX35661.1 - 1.6e-05 23.8 1.5 0.053 12.3 0.1 3.5 1 1 3 4 4 4 3 Nup133 N terminal like Nbas_N PF15492.6 EKX35661.1 - 0.00027 20.4 6.4 3.3 6.9 0.1 5.1 1 1 5 6 6 6 3 Neuroblastoma-amplified sequence, N terminal ANAPC4_WD40 PF12894.7 EKX35661.1 - 0.0045 17.3 5.6 1.6 9.1 0.1 4.3 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain VID27 PF08553.10 EKX35661.1 - 0.055 12.5 2.9 11 5.0 0.1 2.9 1 1 3 4 4 4 0 VID27 C-terminal WD40-like domain DUF3365 PF11845.8 EKX35661.1 - 0.19 12.1 0.1 11 6.3 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3365) Cytochrom_c3_2 PF14537.6 EKX35661.1 - 0.7 10.4 2.5 1.1e+02 3.3 1.4 3.7 2 1 1 3 3 3 0 Cytochrome c3 FG-GAP_2 PF14312.6 EKX35661.1 - 3.1 8.1 19.0 13 6.1 0.2 5.5 6 0 0 6 6 6 0 FG-GAP repeat Ank_2 PF12796.7 EKX35662.1 - 6.4e-49 164.5 8.9 3.4e-10 40.4 0.5 4.9 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX35662.1 - 6e-35 119.2 4.9 3.7e-09 36.9 0.0 6.4 5 2 2 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX35662.1 - 1.4e-30 105.0 10.4 0.0016 18.7 0.0 8.2 3 1 4 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX35662.1 - 1e-25 86.9 5.1 0.14 12.8 0.0 9.1 9 0 0 9 9 9 8 Ankyrin repeat Ank PF00023.30 EKX35662.1 - 7.8e-14 51.4 4.7 0.72 10.4 0.0 8.9 9 0 0 9 9 9 3 Ankyrin repeat BTHB PF18410.1 EKX35662.1 - 0.00085 19.1 0.0 9.4 6.1 0.0 5.0 4 2 3 7 7 7 1 Basic tilted helix bundle domain AvrM_N PF18247.1 EKX35662.1 - 0.0081 16.1 1.5 3.3e+02 1.3 0.0 6.1 7 0 0 7 7 7 0 Flax-rust effector AvrM N-terminal domain DUF5049 PF16468.5 EKX35662.1 - 0.14 12.0 0.0 35 4.4 0.0 4.4 7 0 0 7 7 7 0 Domain of unknown function (DUF5049) YhfH PF14149.6 EKX35662.1 - 0.29 11.2 2.0 0.84 9.7 0.2 2.9 2 0 0 2 2 2 0 YhfH-like protein Rad50_zn_hook PF04423.14 EKX35663.1 - 0.013 15.3 0.6 0.035 14.0 0.1 2.0 2 0 0 2 2 2 0 Rad50 zinc hook motif Ank_2 PF12796.7 EKX35664.1 - 3.2e-41 139.8 2.3 3.9e-10 40.2 0.1 3.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX35664.1 - 2.6e-29 101.2 0.1 3.2e-07 30.8 0.0 5.9 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX35664.1 - 2e-18 66.2 2.9 0.0078 16.5 0.0 6.3 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX35664.1 - 5.8e-13 47.8 0.8 0.16 12.6 0.0 6.9 7 0 0 7 7 7 2 Ankyrin repeat Ank PF00023.30 EKX35664.1 - 3.2e-10 40.0 0.8 0.82 10.2 0.0 5.9 6 1 0 6 6 6 3 Ankyrin repeat Ins_beta PF03488.14 EKX35664.1 - 0.11 12.5 5.8 4.2 7.5 0.0 4.5 5 0 0 5 5 5 0 Nematode insulin-related peptide beta type BDHCT PF08072.11 EKX35664.1 - 9.8 6.3 8.8 74 3.5 0.1 4.3 5 0 0 5 5 5 0 BDHCT (NUC031) domain U-box PF04564.15 EKX35665.1 - 1.6e-16 60.2 0.0 1.9e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX35665.1 - 1.3e-05 24.9 0.0 1.7e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EKX35665.1 - 0.00017 21.6 0.1 0.00023 21.1 0.1 1.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-NOSIP PF15906.5 EKX35665.1 - 0.0048 17.0 0.0 0.0056 16.8 0.0 1.1 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Glyco_hydro_46 PF01374.18 EKX35666.1 - 2.1e-06 27.5 17.9 0.2 11.3 0.4 6.1 1 1 5 7 7 7 5 Glycosyl hydrolase family 46 DUF1090 PF06476.12 EKX35666.1 - 2.2e-06 27.7 71.9 0.53 10.4 1.4 12.6 3 3 10 13 13 13 9 Protein of unknown function (DUF1090) DUF4170 PF13773.6 EKX35666.1 - 0.088 13.0 0.2 18 5.6 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4170) zf-dskA_traR PF01258.17 EKX35666.1 - 0.095 12.7 12.0 16 5.5 0.1 7.2 8 0 0 8 8 8 0 Prokaryotic dksA/traR C4-type zinc finger DUF3769 PF12600.8 EKX35666.1 - 0.55 9.0 5.4 5.7 5.7 0.1 3.7 2 2 2 4 4 4 0 Protein of unknown function (DUF3769) PSII_Pbs31 PF18240.1 EKX35666.1 - 5.3 7.6 22.9 48 4.5 0.2 8.8 4 4 7 13 13 13 0 Photosystem II Psb31 protein Pkinase_Tyr PF07714.17 EKX35667.1 - 5.3e-32 111.1 0.2 5.8e-32 111.0 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX35667.1 - 2.7e-10 40.1 0.0 3.4e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 EKX35668.1 - 1.8e-29 101.3 16.9 4.7e-08 33.6 0.7 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.8 EKX35668.1 - 0.00062 18.5 2.9 1.5 7.4 0.4 3.0 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EKX35668.1 - 0.0051 15.4 1.1 0.12 10.9 0.0 2.6 1 1 2 3 3 3 2 Cytochrome D1 heme domain Read-through PF16814.5 EKX35668.1 - 0.015 15.1 0.2 17 5.1 0.0 3.4 1 1 3 4 4 4 0 Read-through domain PIF1 PF05970.14 EKX35668.1 - 0.016 14.4 0.0 2.3 7.3 0.0 3.4 3 1 1 4 4 4 0 PIF1-like helicase WD40_like PF17005.5 EKX35668.1 - 0.097 12.0 0.0 15 4.8 0.0 2.8 2 1 1 3 3 3 0 WD40-like domain FG-GAP_2 PF14312.6 EKX35668.1 - 0.26 11.6 11.6 10 6.4 0.1 4.7 5 0 0 5 5 5 0 FG-GAP repeat zf-RING_2 PF13639.6 EKX35669.1 - 6.4e-08 32.8 8.9 6.4e-08 32.8 8.9 1.6 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 EKX35669.1 - 3.1e-06 26.9 6.1 6.4e-06 25.9 6.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EKX35669.1 - 6e-06 26.1 7.4 1.1e-05 25.3 7.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EKX35669.1 - 1.1e-05 25.1 7.4 2.4e-05 24.1 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EKX35669.1 - 0.00063 19.7 0.9 0.001 19.1 0.9 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EKX35669.1 - 0.00082 19.4 6.1 0.00092 19.2 4.7 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EKX35669.1 - 0.0031 17.3 10.7 0.0033 17.2 8.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EKX35669.1 - 0.0033 17.2 5.9 0.0062 16.3 5.9 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FYDLN_acid PF09538.10 EKX35669.1 - 0.0051 17.5 4.1 0.011 16.4 4.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) zf-C3HC4 PF00097.25 EKX35669.1 - 0.0077 16.1 8.3 0.016 15.1 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.11 EKX35669.1 - 0.0096 16.0 5.2 0.021 14.9 5.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) Rtf2 PF04641.12 EKX35669.1 - 0.01 15.3 5.0 0.014 14.8 5.0 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-rbx1 PF12678.7 EKX35669.1 - 0.021 15.1 4.2 0.041 14.2 4.2 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain Tho2 PF11262.8 EKX35669.1 - 0.13 11.4 1.0 0.21 10.8 1.0 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 zf-C3HC4_4 PF15227.6 EKX35669.1 - 0.51 10.5 10.0 0.46 10.7 8.4 1.7 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING Porin_7 PF16956.5 EKX35670.1 - 0.023 14.4 10.8 0.12 12.0 6.5 1.9 1 1 0 1 1 1 0 Putative general bacterial porin Ank_2 PF12796.7 EKX35671.1 - 1.9e-49 166.2 15.9 1.5e-10 41.5 0.1 5.4 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX35671.1 - 8e-34 115.3 12.0 0.0025 18.1 0.0 10.1 2 2 8 10 10 10 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX35671.1 - 2.4e-33 114.0 2.3 1.9e-06 28.3 0.0 6.3 3 1 3 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX35671.1 - 1.5e-22 77.2 11.7 0.37 11.5 0.0 10.1 10 0 0 10 10 10 5 Ankyrin repeat Ank PF00023.30 EKX35671.1 - 1.1e-12 47.8 22.5 3.1 8.4 0.0 10.2 10 0 0 10 10 10 4 Ankyrin repeat Chitin_synth_1N PF08407.11 EKX35671.1 - 3.2e-08 33.4 0.3 25 4.9 0.1 7.7 6 1 3 9 9 9 0 Chitin synthase N-terminal Ins_beta PF03488.14 EKX35671.1 - 5.4e-06 26.3 17.9 20 5.3 0.0 8.9 8 1 1 9 9 9 0 Nematode insulin-related peptide beta type BDHCT PF08072.11 EKX35671.1 - 0.00097 19.2 11.2 51 4.1 0.0 7.2 8 0 0 8 8 8 0 BDHCT (NUC031) domain Hva1_TUDOR PF11160.8 EKX35671.1 - 0.003 17.7 6.2 17 5.6 0.0 6.5 7 0 0 7 7 7 0 Hypervirulence associated proteins TUDOR domain Chol_subst-bind PF09129.11 EKX35671.1 - 0.0035 16.3 0.0 13 4.7 0.0 5.2 2 1 6 8 8 8 1 Cholesterol oxidase, substrate-binding SelR PF01641.18 EKX35671.1 - 0.015 15.4 7.0 2.6 8.1 0.0 5.3 1 1 4 6 6 6 0 SelR domain UNC119_bdg PF15435.6 EKX35671.1 - 0.022 14.3 0.2 33 4.0 0.0 4.5 4 2 1 5 5 5 0 UNC119-binding protein C5orf30 homologue DcpS_C PF11969.8 EKX35672.1 - 5.1e-07 30.2 0.1 8.7e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Glyco_transf_11 PF01531.16 EKX35672.1 - 0.0013 18.0 0.1 0.022 14.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 11 Fib_alpha PF08702.10 EKX35675.1 - 0.0037 17.4 2.4 0.013 15.7 2.4 1.9 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 EKX35675.1 - 0.017 15.2 4.2 0.017 15.2 4.2 2.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus BORCS8 PF10167.9 EKX35675.1 - 0.056 13.4 0.3 0.27 11.2 0.3 2.1 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 8 Sec34 PF04136.15 EKX35675.1 - 0.092 12.6 2.0 0.23 11.4 2.0 1.6 1 0 0 1 1 1 0 Sec34-like family TMPIT PF07851.13 EKX35675.1 - 0.57 9.4 4.0 1.3 8.2 4.0 1.6 1 0 0 1 1 1 0 TMPIT-like protein Syntaxin_2 PF14523.6 EKX35675.1 - 0.91 9.9 5.2 5.4 7.4 3.9 2.5 2 0 0 2 2 2 0 Syntaxin-like protein XendoU PF09412.10 EKX35676.1 - 0.03 13.5 0.1 0.039 13.2 0.1 1.1 1 0 0 1 1 1 0 Endoribonuclease XendoU PH PF00169.29 EKX35678.1 - 0.074 13.6 1.4 0.55 10.8 0.2 2.8 2 1 0 2 2 2 0 PH domain DUF3417 PF11897.8 EKX35678.1 - 0.24 11.9 2.2 2.5 8.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3417) PH_13 PF16652.5 EKX35678.1 - 0.3 10.9 2.1 6.2 6.6 0.6 3.1 2 1 0 2 2 2 0 Pleckstrin homology domain PH_11 PF15413.6 EKX35678.1 - 0.69 10.4 4.6 4.2 7.8 0.8 3.2 2 2 0 2 2 2 0 Pleckstrin homology domain DUF3818 PF12825.7 EKX35679.1 - 0.021 13.8 0.2 0.021 13.8 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) eRF1_1 PF03463.15 EKX35680.1 - 2.7e-45 153.5 0.1 4.2e-45 152.9 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 EKX35680.1 - 9e-29 100.5 0.1 1.4e-28 99.8 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EKX35680.1 - 2.5e-22 79.5 0.0 9e-22 77.7 0.0 2.0 2 0 0 2 2 2 1 eRF1 domain 3 Plant_zn_clust PF10533.9 EKX35680.1 - 0.028 14.4 1.5 0.058 13.4 0.5 2.0 2 0 0 2 2 2 0 Plant zinc cluster domain Mis14 PF08641.12 EKX35681.1 - 0.00012 22.4 9.8 0.00012 22.4 9.8 2.7 1 1 1 2 2 2 1 Kinetochore protein Mis14 like TetR_C_32 PF09209.11 EKX35681.1 - 0.015 15.3 0.2 0.18 11.8 0.0 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TCTP PF00838.17 EKX35681.1 - 0.18 12.2 6.3 0.3 11.4 6.0 1.6 1 1 0 1 1 1 0 Translationally controlled tumour protein C1_2 PF03107.16 EKX35682.1 - 0.097 13.0 4.9 0.21 11.9 4.9 1.6 1 0 0 1 1 1 0 C1 domain G2BR PF18442.1 EKX35684.1 - 0.03 13.9 0.8 0.075 12.7 0.8 1.6 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) ANAPC4_WD40 PF12894.7 EKX35685.1 - 1.5e-39 134.2 0.2 1.1e-09 38.4 0.1 7.4 1 1 7 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EKX35685.1 - 4.3e-30 103.3 14.4 0.0001 23.0 0.0 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EKX35685.1 - 2.8e-12 46.3 0.6 0.47 9.4 0.0 7.2 1 1 6 8 8 8 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EKX35685.1 - 1.5e-07 31.5 0.0 0.07 13.0 0.0 3.7 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 EKX35685.1 - 3.6e-07 28.6 3.8 0.00057 18.0 0.6 2.3 2 1 0 2 2 2 2 IKI3 family Nbas_N PF15492.6 EKX35685.1 - 6.7e-07 28.9 3.2 3.7 6.8 0.0 6.9 2 2 6 8 8 8 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 EKX35685.1 - 6.2e-06 25.1 2.6 0.48 9.0 0.1 4.7 2 2 4 6 6 6 1 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EKX35685.1 - 2.4e-05 23.5 2.3 0.43 9.4 0.1 3.5 3 0 0 3 3 3 2 Partner and localizer of BRCA2 WD40 domain Hira PF07569.11 EKX35685.1 - 0.00026 20.8 3.5 9.9 5.8 0.0 5.7 3 3 4 7 7 7 1 TUP1-like enhancer of split Nucleoporin_N PF08801.11 EKX35685.1 - 0.0014 17.5 0.0 0.34 9.6 0.0 3.6 2 2 1 4 4 4 1 Nup133 N terminal like PD40 PF07676.12 EKX35685.1 - 0.005 16.8 0.3 19 5.4 0.0 4.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat ELYS-bb PF16687.5 EKX35685.1 - 0.02 13.5 0.0 4.4 5.8 0.0 3.0 3 0 0 3 3 3 0 beta-propeller of ELYS nucleoporin DUF5585 PF17823.1 EKX35685.1 - 0.052 12.5 0.1 8.6 5.2 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5585) PSII_BNR PF14870.6 EKX35685.1 - 0.072 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 Coatomer_WDAD PF04053.14 EKX35685.1 - 0.24 10.4 0.0 15 4.5 0.0 2.6 2 1 1 3 3 3 0 Coatomer WD associated region Ank_4 PF13637.6 EKX35686.1 - 3.6e-24 84.8 2.5 2.9e-11 43.7 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX35686.1 - 3.9e-23 81.8 3.6 2.4e-16 60.1 0.9 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX35686.1 - 1.3e-16 60.4 0.0 1.8e-10 40.8 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX35686.1 - 4.4e-15 55.4 0.2 8.6e-07 29.1 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EKX35686.1 - 7.1e-12 44.4 0.3 0.00042 20.5 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat IQ PF00612.27 EKX35687.1 - 0.015 15.0 1.9 0.05 13.4 1.9 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif HECT PF00632.25 EKX35688.1 - 4.1e-63 213.7 0.0 4.9e-63 213.4 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.18 EKX35689.1 - 5.8e-54 180.5 17.7 5.1e-13 49.4 0.0 6.5 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX35689.1 - 7.6e-36 121.2 24.2 4.3e-08 32.7 0.4 5.3 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat Ubie_methyltran PF01209.18 EKX35690.1 - 1.1e-17 64.2 0.3 5.2e-16 58.7 0.1 2.5 2 1 1 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EKX35690.1 - 1.1e-16 61.2 0.1 7.7e-15 55.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX35690.1 - 3.1e-14 53.4 0.2 1.1e-13 51.6 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX35690.1 - 7.5e-13 48.5 0.1 1.4e-12 47.7 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX35690.1 - 4.3e-10 40.2 0.1 1.1e-09 38.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EKX35690.1 - 4.3e-06 26.4 0.1 1.3e-05 24.8 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EKX35690.1 - 1.3e-05 25.1 0.0 2.4e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EKX35690.1 - 0.00034 20.1 0.0 0.00058 19.4 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 EKX35690.1 - 0.0018 17.7 0.4 0.0051 16.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) tRNA_U5-meth_tr PF05958.11 EKX35690.1 - 0.0045 16.0 1.8 0.026 13.5 0.0 2.0 2 0 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_8 PF05148.15 EKX35690.1 - 0.016 15.1 0.2 0.024 14.5 0.2 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase CheR PF01739.18 EKX35690.1 - 0.061 12.8 0.1 0.18 11.3 0.1 1.7 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain Retrotrans_gag PF03732.17 EKX35692.1 - 0.00012 22.2 0.0 0.00024 21.3 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein RWP-RK PF02042.15 EKX35693.1 - 1.6e-15 56.8 0.0 2.2e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX35693.1 - 0.0056 16.4 0.1 0.017 14.9 0.0 1.8 1 1 1 2 2 2 1 Bacterial regulatory protein, Fis family AAA_28 PF13521.6 EKX35694.1 - 3e-20 73.1 0.0 3.4e-20 72.9 0.0 1.0 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EKX35694.1 - 0.00067 19.4 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.10 EKX35694.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 FAM183 PF14886.6 EKX35695.1 - 1.3e-07 32.3 0.3 2.6e-07 31.3 0.3 1.7 1 1 0 1 1 1 1 FAM183A and FAM183B related ADK PF00406.22 EKX35695.1 - 3.7e-06 27.1 0.0 6.4e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Adenylate kinase HrpE PF06188.12 EKX35695.1 - 0.0071 16.2 0.3 0.011 15.6 0.3 1.3 1 0 0 1 1 1 1 HrpE/YscL/FliH and V-type ATPase subunit E AAA_17 PF13207.6 EKX35695.1 - 0.0095 16.4 0.1 0.028 14.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain Rhabdo_NV PF02484.15 EKX35695.1 - 0.067 13.4 0.2 0.13 12.4 0.2 1.5 1 0 0 1 1 1 0 Rhabdovirus Non-virion protein NPBW PF15180.6 EKX35695.1 - 0.22 11.4 1.9 0.44 10.4 0.1 2.2 2 1 0 2 2 2 0 Neuropeptides B and W RRM_1 PF00076.22 EKX35697.1 - 7e-07 29.0 0.0 1.3e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TIP_N PF12457.8 EKX35698.1 - 3.7e-13 49.8 6.6 3.7e-13 49.8 6.6 3.4 2 1 1 3 3 3 1 Tuftelin interacting protein N terminal G-patch PF01585.23 EKX35698.1 - 3.9e-10 39.5 7.1 3.9e-10 39.5 7.1 2.1 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 EKX35698.1 - 9.3e-05 22.4 2.3 9.3e-05 22.4 2.3 3.8 4 1 0 4 4 4 1 G-patch domain WD40 PF00400.32 EKX35699.1 - 7.3e-13 48.8 2.0 0.00046 20.9 0.1 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat Ank_4 PF13637.6 EKX35700.1 - 1.1e-107 351.1 11.5 9.7e-09 35.6 0.0 18.1 13 3 5 18 18 18 17 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX35700.1 - 6.5e-94 308.7 31.4 6.1e-12 46.0 0.4 13.7 1 1 15 16 16 16 16 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX35700.1 - 8.7e-44 147.0 20.7 0.028 14.8 0.0 22.0 8 4 13 22 22 22 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX35700.1 - 4.6e-43 140.2 20.6 0.58 10.9 0.0 24.5 28 0 0 28 28 26 6 Ankyrin repeat Ank PF00023.30 EKX35700.1 - 1.3e-19 69.6 25.8 3.2 8.3 0.0 19.8 23 0 0 23 23 21 2 Ankyrin repeat LtuA PF17446.2 EKX35700.1 - 1.1e-05 25.8 0.0 72 3.9 0.0 7.9 9 0 0 9 9 7 0 Late transcription unit A SF3b10 PF07189.11 EKX35700.1 - 7.4e-05 22.8 4.3 74 3.6 0.0 9.9 15 2 1 16 16 14 0 Splicing factor 3B subunit 10 (SF3b10) Mo-nitro_C PF06967.11 EKX35700.1 - 0.00081 19.3 18.3 2.6e+02 1.7 0.0 14.4 20 0 0 20 20 20 0 Mo-dependent nitrogenase C-terminus PGM_PMM_IV PF00408.20 EKX35700.1 - 0.014 15.6 0.2 33 4.7 0.0 4.7 5 0 0 5 5 3 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain CcmH PF03918.14 EKX35700.1 - 0.033 13.5 0.0 8.8 5.6 0.0 4.4 4 2 1 5 5 5 0 Cytochrome C biogenesis protein Ipi1_N PF12333.8 EKX35700.1 - 0.041 14.5 0.1 27 5.4 0.0 5.5 6 2 3 9 9 9 0 Rix1 complex component involved in 60S ribosome maturation DUF2632 PF10943.8 EKX35700.1 - 0.3 10.6 0.6 4.9 6.6 0.0 3.4 5 0 0 5 5 5 0 Protein of unknown function (DUF2632) DUF983 PF06170.12 EKX35700.1 - 2.3 8.7 6.8 1.2e+02 3.2 0.0 5.9 7 1 0 7 7 6 0 Protein of unknown function (DUF983) T2SS_PulS_OutS PF09691.10 EKX35700.1 - 4.7 7.4 16.1 8.5 6.6 0.1 7.2 5 4 4 9 9 9 0 Type II secretion system pilotin lipoprotein (PulS_OutS) FBPase_3 PF01950.16 EKX35700.1 - 5.3 6.1 6.6 60 2.6 0.0 5.0 6 1 1 7 7 7 0 Fructose-1,6-bisphosphatase Glyco_transf_6 PF03414.13 EKX35700.1 - 5.5 5.7 4.7 16 4.2 0.0 3.8 5 1 1 6 6 6 0 Glycosyltransferase family 6 ERG4_ERG24 PF01222.17 EKX35701.1 - 3.8e-68 230.2 15.8 4.6e-68 229.9 15.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PA14 PF07691.12 EKX35702.1 - 1.2e-26 93.3 0.9 1.6e-14 53.9 0.1 2.3 2 0 0 2 2 2 2 PA14 domain GLEYA PF10528.9 EKX35702.1 - 0.0072 16.7 1.6 6.2 7.3 0.1 3.4 3 0 0 3 3 3 2 GLEYA domain RWP-RK PF02042.15 EKX35703.1 - 1.3e-14 53.9 0.0 2.1e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX35704.1 - 1.8e-14 53.4 0.0 3.1e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain DUF5457 PF17540.2 EKX35706.1 - 0.051 13.7 0.1 0.051 13.7 0.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5457) PCMT PF01135.19 EKX35707.1 - 4.8e-08 33.0 0.0 8.4e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GATase1_like PF07090.11 EKX35707.1 - 0.0027 17.2 0.0 0.0047 16.4 0.0 1.3 1 0 0 1 1 1 1 Putative glutamine amidotransferase SRP-alpha_N PF04086.13 EKX35707.1 - 2 8.2 30.5 3 7.7 30.5 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SAPS PF04499.15 EKX35707.1 - 6 5.5 19.5 10 4.8 19.5 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein LAP1C PF05609.12 EKX35707.1 - 9.6 5.2 23.8 19 4.2 23.8 1.5 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Mito_carr PF00153.27 EKX35712.1 - 1.8e-09 37.4 0.1 3.9e-05 23.5 0.0 2.3 2 1 0 2 2 2 2 Mitochondrial carrier protein GHL6 PF14871.6 EKX35712.1 - 0.12 12.6 0.0 0.17 12.0 0.0 1.3 1 1 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 EGF_2 PF07974.13 EKX35713.1 - 7.1e-07 29.5 36.4 0.0011 19.3 11.2 2.8 2 1 0 2 2 2 2 EGF-like domain hEGF PF12661.7 EKX35713.1 - 0.00012 22.5 24.9 0.0031 18.1 8.4 3.4 4 0 0 4 4 4 2 Human growth factor-like EGF EGF_Tenascin PF18720.1 EKX35713.1 - 0.0019 18.2 6.4 0.0019 18.2 6.4 2.7 3 0 0 3 3 3 2 Tenascin EGF domain I-EGF_1 PF18372.1 EKX35713.1 - 0.031 14.4 5.9 0.031 14.4 5.9 3.1 3 1 0 3 3 3 0 Integrin beta epidermal growth factor like domain 1 EGF PF00008.27 EKX35713.1 - 0.49 10.8 32.1 0.13 12.6 9.3 3.2 3 1 0 3 3 3 0 EGF-like domain Antifungal_pept PF11410.8 EKX35713.1 - 9.1 6.3 18.0 0.93 9.5 3.1 2.6 2 0 0 2 2 2 0 Antifungal peptide TRAF_BIRC3_bd PF16673.5 EKX35715.1 - 0.0038 17.0 1.9 0.015 15.1 0.5 2.8 2 0 0 2 2 2 1 TNF receptor-associated factor BIRC3 binding domain XhlA PF10779.9 EKX35715.1 - 3.1 8.1 5.8 31 4.8 0.6 3.3 2 1 0 2 2 2 0 Haemolysin XhlA cNMP_binding PF00027.29 EKX35716.1 - 0.0035 17.4 0.0 0.0085 16.1 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Dabb PF07876.12 EKX35716.1 - 0.067 13.8 0.4 0.34 11.5 0.1 2.3 2 0 0 2 2 2 0 Stress responsive A/B Barrel Domain GATase_2 PF00310.21 EKX35717.1 - 6.2e-162 539.1 0.0 8.7e-162 538.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 EKX35717.1 - 8.8e-149 495.6 1.9 1.2e-148 495.1 0.8 1.7 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 EKX35717.1 - 1.1e-104 349.8 0.0 2.4e-104 348.7 0.0 1.6 2 0 0 2 2 1 1 Glutamate synthase central domain GXGXG PF01493.19 EKX35717.1 - 2.5e-68 229.4 2.7 4.7e-68 228.5 2.7 1.4 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 EKX35717.1 - 8e-27 94.2 0.1 2.4e-25 89.4 0.1 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 EKX35717.1 - 1.8e-20 72.8 0.1 3.5e-20 71.8 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox PF00070.27 EKX35717.1 - 1.8e-09 38.0 0.0 1.1e-05 25.9 0.1 3.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EKX35717.1 - 3.1e-08 33.7 0.1 3.2e-07 30.5 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EKX35717.1 - 1.1e-07 31.4 0.1 0.017 14.4 0.0 3.7 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EKX35717.1 - 9.5e-06 24.6 0.2 0.00013 20.8 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 EKX35717.1 - 3e-05 23.4 0.1 7e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EKX35717.1 - 0.00012 21.6 0.5 0.00064 19.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EKX35717.1 - 0.00015 21.1 0.0 0.00053 19.3 0.0 1.9 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EKX35717.1 - 0.00016 20.9 1.0 0.00055 19.1 0.0 2.4 3 0 0 3 3 3 1 FAD binding domain Amino_oxidase PF01593.24 EKX35717.1 - 0.00019 20.9 0.1 0.0007 19.0 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.6 EKX35717.1 - 0.00021 21.7 0.0 0.96 9.9 0.0 2.7 2 0 0 2 2 2 2 Putative NAD(P)-binding GIDA PF01134.22 EKX35717.1 - 0.00022 20.4 0.0 0.11 11.6 0.0 2.6 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.24 EKX35717.1 - 0.00036 20.2 0.3 0.0062 16.2 0.0 2.7 1 1 0 2 2 2 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 EKX35717.1 - 0.00044 19.7 0.0 0.056 12.8 0.0 2.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EKX35717.1 - 0.00053 19.4 0.0 0.071 12.4 0.0 2.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 EKX35717.1 - 0.031 14.3 1.4 0.26 11.3 0.1 3.1 4 0 0 4 4 4 0 FAD-NAD(P)-binding TrkA_N PF02254.18 EKX35717.1 - 0.055 13.7 0.0 0.91 9.8 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain AdoHcyase_NAD PF00670.21 EKX35717.1 - 0.21 11.6 0.8 11 6.0 0.3 2.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TFIIA PF03153.13 EKX35718.1 - 8.2e-05 22.8 21.7 0.00012 22.3 21.7 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 EKX35718.1 - 0.00056 18.3 26.2 0.00056 18.3 26.2 1.7 2 0 0 2 2 2 1 Nop14-like family FmiP_Thoc5 PF09766.9 EKX35718.1 - 0.0035 16.7 7.7 0.0035 16.7 7.7 2.0 2 0 0 2 2 2 1 Fms-interacting protein/Thoc5 CPSF100_C PF13299.6 EKX35718.1 - 0.012 15.8 6.9 0.012 15.8 6.9 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Serinc PF03348.15 EKX35718.1 - 0.038 12.9 0.2 0.064 12.2 0.2 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) Syntaxin_2 PF14523.6 EKX35718.1 - 0.044 14.1 1.5 0.044 14.1 1.5 1.7 2 0 0 2 2 1 0 Syntaxin-like protein Trypan_PARP PF05887.11 EKX35718.1 - 0.2 11.6 20.8 0.35 10.9 20.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PIP5K PF01504.18 EKX35718.1 - 0.46 9.7 8.1 2.1 7.5 4.0 2.1 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF2052 PF09747.9 EKX35718.1 - 0.73 9.9 30.3 0.12 12.5 21.0 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Vfa1 PF08432.10 EKX35718.1 - 0.95 9.8 21.7 0.8 10.0 14.3 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF4746 PF15928.5 EKX35718.1 - 0.99 8.8 26.9 2.3 7.6 18.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) DNA_pol_phi PF04931.13 EKX35718.1 - 1.2 7.1 47.6 0.07 11.2 41.3 1.8 2 0 0 2 2 2 0 DNA polymerase phi Sporozoite_P67 PF05642.11 EKX35718.1 - 1.5 6.8 15.9 0.64 8.0 12.1 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen RNA_pol_Rpc4 PF05132.14 EKX35718.1 - 1.5 9.2 9.2 0.14 12.6 4.0 1.8 2 0 0 2 2 2 0 RNA polymerase III RPC4 SpoIIP PF07454.11 EKX35718.1 - 1.8 8.0 12.9 0.13 11.6 7.0 1.8 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) SID-1_RNA_chan PF13965.6 EKX35718.1 - 1.9 6.8 8.7 0.053 11.9 2.8 1.3 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 DUF4834 PF16118.5 EKX35718.1 - 2.3 9.3 8.5 0.83 10.7 3.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Cwf_Cwc_15 PF04889.12 EKX35718.1 - 3.7 7.2 37.1 0.1 12.3 26.0 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Usp PF00582.26 EKX35718.1 - 5.6 7.5 12.6 0.38 11.3 6.6 2.0 2 1 0 2 2 2 0 Universal stress protein family SDA1 PF05285.12 EKX35718.1 - 5.9 6.2 37.1 0.18 11.2 29.6 1.9 2 0 0 2 2 2 0 SDA1 FYDLN_acid PF09538.10 EKX35718.1 - 7 7.4 36.7 1.9 9.2 29.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) RR_TM4-6 PF06459.12 EKX35718.1 - 8.1 6.2 19.1 0.33 10.7 11.1 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 WW PF00397.26 EKX35719.1 - 5.3e-09 36.0 1.0 9.5e-09 35.2 1.0 1.5 1 0 0 1 1 1 1 WW domain BUD22 PF09073.10 EKX35719.1 - 0.0059 16.0 9.5 0.0059 16.0 9.5 2.0 1 1 1 2 2 2 1 BUD22 TFIIA PF03153.13 EKX35719.1 - 1.4 8.8 36.4 2 8.3 36.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop25 PF09805.9 EKX35719.1 - 3.4 8.1 41.4 4.2 7.8 8.1 2.3 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) DUF2052 PF09747.9 EKX35719.1 - 9.4 6.3 44.1 3 7.9 25.4 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DUF2894 PF11445.8 EKX35720.1 - 6.6 7.2 19.4 0.56 10.7 12.1 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2894) DUF3085 PF11284.8 EKX35721.1 - 0.031 14.6 0.1 0.071 13.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3085) HSP70 PF00012.20 EKX35722.1 - 1.1e-41 142.8 0.9 1.3e-41 142.5 0.9 1.0 1 0 0 1 1 1 1 Hsp70 protein Raco_middle PF17651.1 EKX35722.1 - 0.16 11.6 0.3 0.87 9.3 0.1 2.1 2 1 0 2 2 2 0 RACo middle region TPR_1 PF00515.28 EKX35723.1 - 5e-08 32.4 2.1 0.00013 21.6 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX35723.1 - 5.1e-07 30.1 1.5 3.2e-06 27.5 2.9 1.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX35723.1 - 2.6e-05 24.0 1.8 1.8 8.9 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX35723.1 - 6.4e-05 23.2 3.5 0.0035 17.6 4.3 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX35723.1 - 0.0051 17.4 3.4 0.7 10.6 2.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX35723.1 - 0.016 15.4 1.7 0.043 14.0 1.7 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EKX35723.1 - 0.032 15.0 3.7 0.087 13.7 2.4 2.3 2 1 1 3 3 3 0 Tetratricopeptide repeat RWP-RK PF02042.15 EKX35724.1 - 1.8e-11 43.8 0.0 2.6e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain MttA_Hcf106 PF02416.16 EKX35724.1 - 0.0013 18.0 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 mttA/Hcf106 family HTH_8 PF02954.19 EKX35724.1 - 0.009 15.8 1.1 1.1 9.1 0.1 2.6 2 1 1 3 3 3 2 Bacterial regulatory protein, Fis family AMP-binding PF00501.28 EKX35725.1 - 2.3e-96 323.0 0.0 3e-96 322.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EKX35725.1 - 5.1e-05 24.2 0.1 0.00014 22.7 0.1 1.8 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Kinesin PF00225.23 EKX35726.1 - 7.6e-108 360.4 0.0 2.1e-107 358.9 0.0 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX35726.1 - 2.8e-24 85.7 0.0 9.8e-24 84.0 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding SAP PF02037.27 EKX35726.1 - 3e-09 36.4 3.0 3e-09 36.4 3.0 2.7 2 0 0 2 2 2 1 SAP domain Telomere_Sde2_2 PF13297.6 EKX35726.1 - 0.3 10.8 5.3 0.46 10.2 0.6 3.2 3 0 0 3 3 3 0 Telomere stability C-terminal NPV_P10 PF05531.12 EKX35726.1 - 3.8 8.0 14.5 0.83 10.2 2.2 4.3 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Ammonium_transp PF00909.21 EKX35727.1 - 1.5e-114 382.8 32.3 1.9e-114 382.5 32.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family FAST_1 PF06743.15 EKX35728.1 - 1.4e-07 31.3 0.0 0.2 11.6 0.0 6.0 7 0 0 7 7 7 2 FAST kinase-like protein, subdomain 1 DUF1601 PF07671.11 EKX35728.1 - 0.012 15.4 21.3 7.2 6.6 0.0 7.7 8 1 0 8 8 8 0 Protein of unknown function (DUF1601) OHCU_decarbox PF09349.10 EKX35728.1 - 0.13 12.8 1.6 0.49 10.9 0.1 2.7 2 2 1 3 3 3 0 OHCU decarboxylase PhageMin_Tail PF10145.9 EKX35728.1 - 0.14 12.0 1.7 4.2 7.2 0.6 3.2 2 1 0 2 2 2 0 Phage-related minor tail protein GAS PF13851.6 EKX35729.1 - 0.00069 19.0 16.8 0.00096 18.6 16.8 1.3 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.11 EKX35729.1 - 0.002 18.0 8.5 0.003 17.4 8.4 1.4 1 1 0 1 1 1 1 Phage minor structural protein GP20 CENP-F_leu_zip PF10473.9 EKX35729.1 - 0.0034 17.4 13.4 0.0041 17.2 13.4 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Effector_1 PF04518.12 EKX35729.1 - 0.0036 16.5 0.9 0.0038 16.4 0.9 1.0 1 0 0 1 1 1 1 Effector from type III secretion system UPF0242 PF06785.11 EKX35729.1 - 0.0067 16.6 11.1 0.0088 16.2 11.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Syntaxin-6_N PF09177.11 EKX35729.1 - 0.06 13.9 5.6 0.074 13.6 5.6 1.2 1 0 0 1 1 1 0 Syntaxin 6, N-terminal CC2-LZ PF16516.5 EKX35729.1 - 0.16 12.3 11.3 0.13 12.6 3.5 2.1 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF3584 PF12128.8 EKX35729.1 - 0.31 8.5 15.2 0.35 8.3 15.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Bap31_Bap29_C PF18035.1 EKX35729.1 - 0.32 11.0 12.6 0.62 10.1 6.5 2.8 2 1 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4407 PF14362.6 EKX35729.1 - 0.61 9.4 6.1 0.75 9.1 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2681 PF10883.8 EKX35729.1 - 0.76 10.2 13.3 0.16 12.4 4.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) DUF334 PF03904.13 EKX35729.1 - 1.1 8.7 10.7 2.6 7.5 9.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF334) DUF4398 PF14346.6 EKX35729.1 - 3.2 8.4 11.0 36 5.1 11.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4398) TMPIT PF07851.13 EKX35729.1 - 4.5 6.4 7.9 5.5 6.1 7.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF4404 PF14357.6 EKX35729.1 - 6.1 7.6 10.8 16 6.2 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF883 PF05957.13 EKX35729.1 - 8.4 7.1 11.5 2.2 8.9 5.2 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Fer4_5 PF12801.7 EKX35730.1 - 1.6e-11 44.0 10.9 1.5e-05 24.8 0.4 2.9 2 0 0 2 2 2 2 4Fe-4S binding domain Sigma54_activat PF00158.26 EKX35730.1 - 0.024 14.3 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EKX35730.1 - 0.049 13.7 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Fer4_9 PF13187.6 EKX35730.1 - 0.54 10.5 10.4 13 6.1 10.4 2.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain Myb_DNA-binding PF00249.31 EKX35731.1 - 9e-08 32.2 0.0 4e-07 30.1 0.0 2.0 1 1 0 1 1 1 1 Myb-like DNA-binding domain TEA PF01285.18 EKX35731.1 - 0.1 12.7 0.0 0.3 11.2 0.0 1.8 1 1 0 1 1 1 0 TEA/ATTS domain Chloroa_b-bind PF00504.21 EKX35732.1 - 9e-14 52.3 0.0 1.1e-13 52.0 0.0 1.3 1 1 0 1 1 1 1 Chlorophyll A-B binding protein Neisseria_TspB PF05616.13 EKX35733.1 - 0.0022 16.6 1.8 0.0024 16.4 1.8 1.0 1 0 0 1 1 1 1 Neisseria meningitidis TspB protein TMEM214 PF10151.9 EKX35733.1 - 0.26 9.7 4.8 0.29 9.5 4.8 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Raftlin PF15250.6 EKX35733.1 - 0.28 9.9 4.2 0.33 9.6 4.2 1.1 1 0 0 1 1 1 0 Raftlin DUF5423 PF17461.2 EKX35733.1 - 0.55 9.0 8.9 0.7 8.7 8.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Presenilin PF01080.17 EKX35733.1 - 0.68 8.6 3.4 0.67 8.7 3.4 1.0 1 0 0 1 1 1 0 Presenilin SRP-alpha_N PF04086.13 EKX35733.1 - 2.9 7.7 13.2 3.6 7.4 13.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CDC45 PF02724.14 EKX35733.1 - 6.9 4.8 7.2 7.7 4.7 7.2 1.0 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 EKX35733.1 - 8.1 5.1 6.2 8.2 5.1 6.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Herpes_UL17 PF04559.12 EKX35734.1 - 0.7 8.6 4.4 0.91 8.2 4.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL17 protein RWP-RK PF02042.15 EKX35735.1 - 1.2e-08 34.8 0.0 2.6e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX35736.1 - 3.4e-12 46.1 0.1 6.1e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain RNA_pol_Rpo13 PF12136.8 EKX35736.1 - 0.096 12.6 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain RWP-RK PF02042.15 EKX35737.1 - 5.2e-12 45.5 0.1 8.5e-12 44.9 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX35738.1 - 2.4e-12 46.6 0.0 3.7e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 RWP-RK domain EF-hand_6 PF13405.6 EKX35739.1 - 2.9e-06 26.7 0.2 7.1e-05 22.4 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EKX35739.1 - 3.1e-06 26.3 1.1 1.3e-05 24.4 0.1 2.6 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 EKX35739.1 - 5.8e-06 26.7 3.6 2.2e-05 24.8 1.5 2.6 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX35739.1 - 0.003 17.0 0.1 0.0094 15.4 0.1 1.9 1 0 0 1 1 1 1 EF hand CCP_MauG PF03150.14 EKX35739.1 - 0.025 15.2 0.1 0.032 14.9 0.1 1.2 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase DUF3727 PF12527.8 EKX35740.1 - 4.2e-07 30.1 5.3 2.2e-05 24.6 0.1 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF3727) DUF1292 PF06949.11 EKX35740.1 - 0.004 18.1 0.7 0.004 18.1 0.7 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1292) ASRT PF07100.11 EKX35740.1 - 0.07 13.2 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Anabaena sensory rhodopsin transducer CHAT PF12770.7 EKX35741.1 - 0.15 11.4 0.1 0.16 11.3 0.1 1.0 1 0 0 1 1 1 0 CHAT domain Ank_4 PF13637.6 EKX35742.1 - 4.8e-18 65.3 0.5 9.6e-13 48.4 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX35742.1 - 2.9e-16 59.8 0.2 2e-11 44.3 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX35742.1 - 1.4e-12 46.6 0.2 0.1 13.2 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EKX35742.1 - 4.5e-12 46.0 1.0 2.7e-05 24.4 0.1 3.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX35742.1 - 8.7e-11 41.8 2.0 0.0016 18.8 0.2 3.5 4 0 0 4 4 4 3 Ankyrin repeat DUF2520 PF10728.9 EKX35742.1 - 0.079 12.7 0.1 0.16 11.7 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF2520) Zn_clus PF00172.18 EKX35743.1 - 0.0062 16.6 8.1 0.01 15.9 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HLH PF00010.26 EKX35744.1 - 3.2e-07 30.2 2.4 6.5e-07 29.2 2.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SIKE PF05769.11 EKX35744.1 - 0.00088 19.3 2.7 0.0014 18.6 2.7 1.2 1 0 0 1 1 1 1 SIKE family NRBF2 PF08961.10 EKX35744.1 - 0.0031 17.1 0.7 0.016 14.8 0.4 2.1 2 0 0 2 2 2 1 Nuclear receptor-binding factor 2, autophagy regulator Mating_C PF12737.7 EKX35744.1 - 0.006 15.9 0.1 0.014 14.7 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of homeodomain 1 PikAIV_N PF18605.1 EKX35744.1 - 5.2 6.7 8.3 8.4 6.1 2.3 2.7 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Cep57_MT_bd PF06657.13 EKX35745.1 - 0.072 13.6 0.1 0.072 13.6 0.1 2.0 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 MerR-DNA-bind PF09278.11 EKX35745.1 - 1.2 9.8 10.4 2.6 8.6 0.8 3.2 2 1 1 3 3 3 0 MerR, DNA binding Casc1_N PF15927.5 EKX35745.1 - 1.3 8.6 13.0 0.39 10.4 9.7 1.7 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus ZapB PF06005.12 EKX35745.1 - 1.9 9.0 7.1 60 4.2 0.0 2.3 2 0 0 2 2 2 0 Cell division protein ZapB Epiglycanin_TR PF05647.11 EKX35745.1 - 2.2 8.3 12.5 5.2 7.1 12.5 1.6 1 0 0 1 1 1 0 Tandem-repeating region of mucin, epiglycanin-like GPI-anchored PF10342.9 EKX35746.1 - 6.1e-06 26.9 0.2 0.021 15.6 0.0 3.0 3 1 0 3 3 3 2 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PAP1 PF08601.10 EKX35746.1 - 0.037 13.8 20.4 0.076 12.7 5.1 2.1 2 0 0 2 2 2 0 Transcription factor PAP1 SAP30_Sin3_bdg PF13867.6 EKX35749.1 - 3.4e-11 43.3 0.1 7.5e-11 42.2 0.1 1.6 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Succ_CoA_lig PF13607.6 EKX35749.1 - 0.04 13.7 0.1 0.066 13.0 0.1 1.3 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain DUF2390 PF09523.10 EKX35749.1 - 0.12 12.7 0.2 13 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) YqeY PF09424.10 EKX35750.1 - 5e-06 26.6 0.4 7e-06 26.2 0.4 1.2 1 0 0 1 1 1 1 Yqey-like protein CDC37_C PF08564.10 EKX35750.1 - 0.083 13.0 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Cdc37 C terminal domain Frataxin_Cyay PF01491.16 EKX35751.1 - 2.2e-30 104.9 0.0 3.1e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Frataxin-like domain DUF1908 PF08926.11 EKX35751.1 - 0.029 13.5 0.0 0.031 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) Holin_BhlA PF10960.8 EKX35751.1 - 0.15 12.0 0.9 0.29 11.1 0.9 1.4 1 0 0 1 1 1 0 BhlA holin family DNA_pol_A PF00476.20 EKX35753.1 - 3.4e-48 164.6 0.0 2e-37 129.2 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 EKX35753.1 - 5.3e-10 39.3 0.0 1.5e-09 37.8 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease MSG PF02349.15 EKX35754.1 - 0.00014 22.0 32.2 0.12 12.5 3.9 4.3 1 1 4 5 5 5 5 Major surface glycoprotein DUF3796 PF12676.7 EKX35754.1 - 0.0014 19.0 7.4 7.3 7.0 3.4 3.6 1 1 1 2 2 2 2 Protein of unknown function (DUF3796) ABC_membrane_2 PF06472.15 EKX35754.1 - 6.7 6.0 9.2 7.7 5.8 0.5 2.5 1 1 1 2 2 2 0 ABC transporter transmembrane region 2 RRM_1 PF00076.22 EKX35755.1 - 7.4e-13 48.1 0.0 1.7e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.14 EKX35755.1 - 0.77 8.0 14.8 1 7.6 14.8 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 EKX35755.1 - 8.8 5.8 16.9 11 5.5 16.9 1.1 1 0 0 1 1 1 0 PPP4R2 AMP-binding PF00501.28 EKX35756.1 - 1.2e-89 300.9 0.0 1.5e-89 300.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EKX35756.1 - 0.0011 19.9 0.0 0.0029 18.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ank_2 PF12796.7 EKX35757.1 - 4.7e-15 55.9 0.2 3.1e-11 43.7 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX35757.1 - 2.1e-14 53.7 0.2 2e-08 34.6 0.2 4.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX35757.1 - 3.7e-10 39.9 0.5 0.0011 19.3 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX35757.1 - 1.5e-09 37.3 0.7 0.0033 17.8 0.0 4.8 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 EKX35757.1 - 1.3e-08 34.8 0.7 0.0076 16.7 0.2 4.1 5 0 0 5 5 5 2 Ankyrin repeat Imm49 PF15575.6 EKX35757.1 - 0.0024 17.7 0.1 0.0045 16.8 0.0 1.5 1 1 0 1 1 1 1 Immunity protein 49 MGDG_synth PF06925.11 EKX35758.1 - 2.2e-25 89.7 0.0 3.1e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_tran_28_C PF04101.16 EKX35758.1 - 1.1e-11 45.0 0.0 1.7e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glycos_transf_1 PF00534.20 EKX35758.1 - 4.3e-07 29.6 0.0 7.2e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EKX35758.1 - 0.0001 22.7 0.0 0.00021 21.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF913 PF06025.12 EKX35759.1 - 0.04 12.9 8.0 0.044 12.7 6.2 2.1 1 1 0 1 1 1 0 Domain of Unknown Function (DUF913) Cadherin_4 PF17803.1 EKX35761.1 - 0.011 16.3 4.2 8.6 7.1 0.0 4.8 6 0 0 6 6 6 0 Bacterial cadherin-like domain Cyclin_N PF00134.23 EKX35762.1 - 9e-45 151.5 3.9 2.6e-44 150.0 1.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EKX35762.1 - 4.1e-29 101.1 4.7 1.5e-28 99.3 3.3 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain Peptidase_M43 PF05572.13 EKX35762.1 - 0.025 14.5 0.4 0.84 9.5 0.0 2.3 2 0 0 2 2 2 0 Pregnancy-associated plasma protein-A S6PP PF05116.13 EKX35762.1 - 0.033 13.7 0.1 0.061 12.8 0.1 1.4 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase DUF3007 PF11460.8 EKX35763.1 - 0.042 14.1 0.2 0.13 12.6 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) HemY_N PF07219.13 EKX35763.1 - 0.74 10.0 9.2 2.5 8.3 3.3 3.1 2 1 1 3 3 3 0 HemY protein N-terminus Ac76 PF05814.11 EKX35763.1 - 2.3 8.3 8.4 4.1 7.5 2.4 2.4 1 1 1 2 2 2 0 Orf76 (Ac76) FKBP_C PF00254.28 EKX35764.1 - 3.4e-22 78.6 0.0 3.8e-22 78.4 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PPP4R2 PF09184.11 EKX35765.1 - 0.0032 17.1 14.9 0.0053 16.4 14.9 1.3 1 0 0 1 1 1 1 PPP4R2 Nop14 PF04147.12 EKX35765.1 - 0.0035 15.7 14.2 0.0043 15.3 14.2 1.1 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.10 EKX35765.1 - 0.004 16.6 11.1 0.0056 16.1 11.1 1.1 1 0 0 1 1 1 1 BUD22 Pox_Ag35 PF03286.14 EKX35765.1 - 0.011 15.5 8.1 0.023 14.5 8.1 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SDA1 PF05285.12 EKX35765.1 - 0.02 14.3 14.1 0.024 14.1 14.1 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 EKX35765.1 - 0.038 12.3 9.3 0.043 12.1 9.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 EKX35765.1 - 0.093 11.9 1.0 0.12 11.6 1.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CNDH2_C PF16858.5 EKX35765.1 - 0.16 11.8 7.3 0.24 11.2 7.3 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term RPN2_C PF18004.1 EKX35765.1 - 0.18 11.7 2.4 0.28 11.1 2.4 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Cwf_Cwc_15 PF04889.12 EKX35765.1 - 0.2 11.4 17.7 0.32 10.7 17.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.13 EKX35765.1 - 0.2 11.5 11.6 0.4 10.5 11.6 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleo_P87 PF07267.11 EKX35765.1 - 0.33 9.7 7.6 0.51 9.1 7.6 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 COX6B PF02297.17 EKX35765.1 - 2.8 8.2 11.2 1.5 9.1 5.6 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIb DUF2722 PF10846.8 EKX35765.1 - 4.8 6.0 11.0 6.6 5.6 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF913 PF06025.12 EKX35765.1 - 6.6 5.6 7.6 1.1e+02 1.5 8.1 2.1 1 1 1 2 2 2 0 Domain of Unknown Function (DUF913) DUF948 PF06103.11 EKX35766.1 - 0.18 12.1 1.0 0.52 10.6 1.0 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Peptidase_C37 PF05416.12 EKX35766.1 - 0.25 9.8 3.6 0.35 9.3 3.6 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase DUF4407 PF14362.6 EKX35766.1 - 0.38 10.1 6.2 0.68 9.2 6.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1351 PF07083.11 EKX35766.1 - 0.55 10.0 10.5 4.8 6.9 10.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1351) M11L PF11099.8 EKX35766.1 - 0.74 10.1 2.4 1.3 9.3 2.4 1.3 1 0 0 1 1 1 0 Apoptosis regulator M11L like MRP-S26 PF14943.6 EKX35766.1 - 3.7 7.4 17.6 7.6 6.4 17.6 1.5 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 TMF_DNA_bd PF12329.8 EKX35767.1 - 9.5e-05 22.3 28.3 0.00033 20.6 10.3 3.2 1 1 2 3 3 3 2 TATA element modulatory factor 1 DNA binding KLRAQ PF10205.9 EKX35767.1 - 0.022 15.0 10.2 0.022 15.0 10.2 2.7 2 1 1 3 3 3 0 Predicted coiled-coil domain-containing protein YabA PF06156.13 EKX35767.1 - 0.039 14.6 19.2 1.2 9.8 6.0 2.8 1 1 0 2 2 2 0 Initiation control protein YabA UvrA_DNA-bind PF17755.1 EKX35767.1 - 0.043 14.2 1.2 0.11 12.8 1.2 1.8 1 0 0 1 1 1 0 UvrA DNA-binding domain TSC22 PF01166.18 EKX35767.1 - 0.052 13.9 9.2 0.087 13.2 0.2 3.1 2 1 0 2 2 2 0 TSC-22/dip/bun family Lebercilin PF15619.6 EKX35767.1 - 0.092 12.4 27.6 0.41 10.3 27.4 2.1 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease SlyX PF04102.12 EKX35767.1 - 0.32 11.7 16.0 0.22 12.1 3.6 3.7 2 1 1 3 3 3 0 SlyX Fib_alpha PF08702.10 EKX35767.1 - 0.54 10.4 18.8 0.3 11.3 5.6 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family HOOK PF05622.12 EKX35767.1 - 0.7 8.0 29.8 0.28 9.3 12.2 2.1 1 1 1 2 2 2 0 HOOK protein DUF812 PF05667.11 EKX35767.1 - 1 8.1 26.6 2.1 7.1 26.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) ADIP PF11559.8 EKX35767.1 - 1.2 9.2 27.4 0.1 12.7 3.1 3.4 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 EKX35767.1 - 1.4 8.7 27.5 0.58 9.9 6.0 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF724) LPP PF04728.13 EKX35767.1 - 6.6 7.2 11.1 1.6 9.1 1.1 3.5 2 1 0 3 3 3 0 Lipoprotein leucine-zipper PhyH PF05721.13 EKX35768.1 - 4.5e-08 33.6 0.9 3.8e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) GlutR_N PF05201.15 EKX35768.1 - 0.032 14.0 1.2 0.062 13.1 1.2 1.5 1 1 0 1 1 1 0 Glutamyl-tRNAGlu reductase, N-terminal domain LUC7 PF03194.15 EKX35768.1 - 0.17 11.6 9.3 0.24 11.1 9.3 1.1 1 0 0 1 1 1 0 LUC7 N_terminus Vpu PF00558.19 EKX35768.1 - 3.3 7.6 6.3 1.4 8.7 2.6 2.2 2 0 0 2 2 2 0 Vpu protein Methyltransf_21 PF05050.12 EKX35769.1 - 2.5e-06 27.6 0.0 3.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain V_cholerae_RfbT PF05575.11 EKX35769.1 - 0.1 11.8 0.0 0.21 10.8 0.0 1.5 1 1 0 1 1 1 0 Vibrio cholerae RfbT protein Pkinase_Tyr PF07714.17 EKX35770.1 - 2.2e-48 164.8 0.0 3.2e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX35770.1 - 4.4e-31 108.2 0.0 6.3e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain U-box PF04564.15 EKX35770.1 - 8.2e-12 45.1 0.0 1.4e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 U-box domain Kdo PF06293.14 EKX35770.1 - 0.001 18.4 0.1 0.0016 17.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX35770.1 - 0.0039 17.2 0.1 0.0065 16.4 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-NOSIP PF15906.5 EKX35770.1 - 0.013 15.6 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Pkinase_fungal PF17667.1 EKX35770.1 - 0.032 13.0 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase LRR_8 PF13855.6 EKX35771.1 - 7.6e-126 409.9 114.5 1.6e-16 59.8 3.7 7.6 1 1 11 12 12 12 12 Leucine rich repeat LRR_5 PF13306.6 EKX35771.1 - 4.3e-37 126.9 0.1 9e-13 48.3 0.0 3.4 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 EKX35771.1 - 8.9e-35 118.2 46.6 2.6e-06 27.7 0.5 8.0 2 2 6 9 9 9 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX35771.1 - 5.3e-16 56.7 36.3 1.2 9.9 0.0 13.3 13 1 0 13 13 13 7 Leucine Rich Repeat LRR_9 PF14580.6 EKX35771.1 - 7.9e-10 38.5 9.9 0.039 13.4 0.2 4.3 1 1 4 5 5 5 4 Leucine-rich repeat Fimbrial_CS1 PF04449.12 EKX35771.1 - 0.034 14.3 0.0 9.6 6.3 0.0 2.4 2 0 0 2 2 2 0 CS1 type fimbrial major subunit LRR_6 PF13516.6 EKX35771.1 - 0.26 11.4 49.8 8.8 6.7 0.4 11.8 12 0 0 12 12 12 0 Leucine Rich repeat ArsA_ATPase PF02374.15 EKX35772.1 - 9.8e-66 222.0 0.0 1.3e-65 221.6 0.0 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.23 EKX35772.1 - 3.1e-11 43.4 0.0 6e-11 42.5 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EKX35772.1 - 4.5e-11 43.0 0.0 1.2e-10 41.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain ParA PF10609.9 EKX35772.1 - 6.8e-06 25.7 2.0 1.5e-05 24.6 2.0 1.6 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 EKX35772.1 - 3.6e-05 23.4 0.1 5.5e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 EKX35772.1 - 0.00013 21.6 0.3 0.0064 16.1 0.1 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MeaB PF03308.16 EKX35772.1 - 0.00037 19.6 1.8 0.00074 18.6 0.3 2.2 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CBP_BcsQ PF06564.12 EKX35772.1 - 0.0027 17.2 0.1 0.0067 15.9 0.1 1.6 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ KR PF08659.10 EKX35772.1 - 0.0063 16.4 1.3 0.24 11.3 0.1 2.4 2 0 0 2 2 2 1 KR domain ATP_bind_1 PF03029.17 EKX35772.1 - 0.0095 15.7 0.3 0.054 13.3 0.3 2.1 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein DUF1611 PF07755.11 EKX35772.1 - 0.012 15.0 0.4 0.043 13.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain DUF4143 PF13635.6 EKX35772.1 - 0.013 15.7 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4143) LpxK PF02606.14 EKX35772.1 - 0.033 13.3 0.2 0.098 11.7 0.1 1.7 2 0 0 2 2 2 0 Tetraacyldisaccharide-1-P 4'-kinase IstB_IS21 PF01695.17 EKX35772.1 - 0.046 13.4 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 EKX35772.1 - 0.058 12.7 0.5 0.1 11.8 0.1 1.6 2 0 0 2 2 2 0 Zeta toxin PhoH PF02562.16 EKX35772.1 - 0.08 12.4 0.1 0.16 11.4 0.1 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 EKX35772.1 - 0.12 12.8 3.7 0.12 12.8 0.2 2.3 1 1 0 2 2 2 0 AAA ATPase domain DUF815 PF05673.13 EKX35772.1 - 0.19 10.9 0.5 0.36 9.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SIKE PF05769.11 EKX35772.1 - 0.29 11.1 1.0 0.93 9.4 0.1 2.1 2 1 1 3 3 2 0 SIKE family 4HBT PF03061.22 EKX35773.1 - 2.3e-10 40.7 0.2 6.8e-06 26.4 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily Glyco_transf_92 PF01697.27 EKX35774.1 - 1.7e-27 96.7 0.6 3.3e-27 95.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 EKX35774.1 - 6.2e-15 55.5 0.3 1.6e-14 54.1 0.3 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Methyltransf_23 PF13489.6 EKX35774.1 - 0.0012 18.6 0.0 0.003 17.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain rve PF00665.26 EKX35774.1 - 0.1 12.8 0.0 0.27 11.4 0.0 1.8 2 0 0 2 2 2 0 Integrase core domain zf-RING_2 PF13639.6 EKX35775.1 - 5.4e-11 42.7 9.5 5.4e-11 42.7 9.5 2.5 2 0 0 2 2 2 1 Ring finger domain TPR_12 PF13424.6 EKX35775.1 - 2.6e-08 34.0 0.5 6.8e-08 32.7 0.5 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat zf-rbx1 PF12678.7 EKX35775.1 - 2.9e-08 33.9 8.5 2.9e-08 33.9 8.5 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EKX35775.1 - 4.6e-08 32.8 8.8 4.6e-08 32.8 8.8 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX35775.1 - 3.4e-07 30.0 18.9 6.2e-07 29.2 7.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.17 EKX35775.1 - 3.5e-07 29.8 2.6 0.0039 17.2 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-RING_11 PF17123.5 EKX35775.1 - 1.5e-06 27.9 4.4 1.5e-06 27.9 4.4 1.9 2 0 0 2 2 1 1 RING-like zinc finger TPR_16 PF13432.6 EKX35775.1 - 3.7e-06 27.5 1.4 3.7e-06 27.5 1.4 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat zf-RING_UBOX PF13445.6 EKX35775.1 - 5.2e-06 26.4 13.0 1.9e-05 24.6 4.6 2.5 2 0 0 2 2 2 1 RING-type zinc-finger TPR_14 PF13428.6 EKX35775.1 - 8.5e-06 26.2 6.3 0.034 15.0 0.1 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX35775.1 - 1.2e-05 24.9 0.5 0.025 14.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX35775.1 - 1.7e-05 24.5 1.9 0.00035 20.4 0.1 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat zf-RING_5 PF14634.6 EKX35775.1 - 3.5e-05 23.7 19.3 9.8e-05 22.2 6.5 2.4 2 0 0 2 2 2 2 zinc-RING finger domain TPR_10 PF13374.6 EKX35775.1 - 3.7e-05 23.4 3.4 0.0026 17.6 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-C3HC4_3 PF13920.6 EKX35775.1 - 7.1e-05 22.6 17.0 0.00012 21.9 5.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) TPR_19 PF14559.6 EKX35775.1 - 0.00082 19.8 0.8 0.019 15.4 0.1 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat zf-ANAPC11 PF12861.7 EKX35775.1 - 0.0054 16.7 4.4 0.0054 16.7 4.4 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_5 PF12688.7 EKX35775.1 - 0.02 15.1 0.5 0.047 13.9 0.5 1.6 1 0 0 1 1 1 0 Tetratrico peptide repeat TPR_4 PF07721.14 EKX35775.1 - 0.025 15.2 0.0 0.025 15.2 0.0 4.0 4 0 0 4 4 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX35775.1 - 0.029 14.4 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 EKX35775.1 - 0.04 13.6 0.0 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 TPR repeat Prok-RING_4 PF14447.6 EKX35775.1 - 0.2 11.5 18.9 0.1 12.5 7.3 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EKX35775.1 - 1.7 8.5 13.4 4.4 7.2 7.4 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 EKX35775.1 - 5 7.3 9.6 13 6.0 9.6 1.7 1 0 0 1 1 1 0 RING-variant domain DUF727 PF05303.12 EKX35776.1 - 3.9e-12 46.2 0.0 5.7e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF727) UreD PF01774.17 EKX35777.1 - 1.2e-49 169.1 0.0 1.6e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein Aminotran_3 PF00202.21 EKX35777.1 - 0.036 12.7 0.0 0.048 12.3 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-III XRN_N PF03159.18 EKX35777.1 - 0.21 11.0 1.1 0.3 10.5 0.0 1.7 2 0 0 2 2 2 0 XRN 5'-3' exonuclease N-terminus Methyltr_RsmB-F PF01189.17 EKX35778.1 - 2.7e-35 121.9 0.0 5e-35 121.0 0.0 1.4 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EKX35778.1 - 0.00051 20.2 0.0 0.00079 19.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF2431 PF10354.9 EKX35778.1 - 0.18 12.1 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) PseudoU_synth_2 PF00849.22 EKX35779.1 - 6.5e-14 52.3 0.1 9.7e-14 51.8 0.1 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 EKX35779.1 - 1.1e-05 25.0 0.1 3.4e-05 23.5 0.1 1.9 1 1 0 1 1 1 1 S4 domain Sugarporin_N PF11471.8 EKX35780.1 - 0.022 14.7 1.1 0.052 13.5 1.1 1.7 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension GAS PF13851.6 EKX35780.1 - 0.077 12.3 4.2 0.12 11.7 4.2 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding FAM76 PF16046.5 EKX35780.1 - 0.28 10.5 6.3 0.053 12.9 1.5 1.9 1 1 1 2 2 2 0 FAM76 protein TMCO5 PF14992.6 EKX35780.1 - 0.38 10.3 2.8 0.59 9.7 2.8 1.4 1 1 0 1 1 1 0 TMCO5 family Muted PF14942.6 EKX35780.1 - 0.39 11.0 5.8 0.4 11.0 4.5 1.7 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF724 PF05266.14 EKX35780.1 - 0.69 9.7 5.0 0.29 11.0 2.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Atg14 PF10186.9 EKX35780.1 - 1.8 7.6 7.7 2.4 7.2 7.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LCCL PF03815.19 EKX35781.1 - 4.5e-09 36.3 0.4 1e-08 35.2 0.4 1.6 1 0 0 1 1 1 1 LCCL domain Gag_p24 PF00607.20 EKX35781.1 - 0.074 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) Ephrin_rec_like PF07699.13 EKX35782.1 - 1.9e-21 75.5 41.0 2.7e-07 30.2 0.5 5.6 5 1 0 5 5 5 5 Putative ephrin-receptor like CHB_HEX_C_1 PF13290.6 EKX35782.1 - 1.1e-16 60.6 1.3 2e-16 59.7 1.3 1.5 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 EKX35782.1 - 3.5e-12 46.3 1.7 8.1e-12 45.1 1.7 1.6 1 0 0 1 1 1 1 Fn3 associated TNFR_c6 PF00020.18 EKX35782.1 - 0.17 12.3 26.8 3.7 8.0 0.2 5.9 6 0 0 6 6 6 0 TNFR/NGFR cysteine-rich region SAP18 PF06487.12 EKX35784.1 - 9.9e-30 103.5 0.1 1.1e-29 103.3 0.1 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) PB1 PF00564.24 EKX35784.1 - 0.0045 16.9 0.1 0.014 15.3 0.0 1.8 2 0 0 2 2 2 1 PB1 domain ABC1 PF03109.16 EKX35784.1 - 0.1 12.8 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 ABC1 family E1-E2_ATPase PF00122.20 EKX35785.1 - 7.7e-47 159.1 2.7 7.8e-47 159.1 0.6 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EKX35785.1 - 4.6e-22 78.6 0.0 1.1e-21 77.4 0.0 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EKX35785.1 - 1.5e-21 77.7 4.1 2.3e-20 73.8 1.8 3.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EKX35785.1 - 1e-15 57.2 0.0 2.1e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EKX35785.1 - 1.7e-10 40.9 0.0 4e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EKX35785.1 - 3.7e-07 30.2 0.6 6.7e-05 22.8 0.2 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EKX35785.1 - 0.00053 20.5 0.0 0.0015 19.0 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase EF-hand_1 PF00036.32 EKX35787.1 - 7.8e-06 25.1 0.2 1.8e-05 24.0 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 EKX35787.1 - 0.00028 20.2 1.3 0.00061 19.2 0.3 2.1 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EKX35787.1 - 0.00052 20.4 0.1 0.0013 19.1 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX35787.1 - 0.0059 16.4 0.3 0.031 14.2 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 EKX35787.1 - 0.03 14.2 0.0 0.082 12.8 0.0 1.8 1 1 0 1 1 1 0 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX35787.1 - 0.055 13.8 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region dCMP_cyt_deam_1 PF00383.23 EKX35788.1 - 6.2e-17 61.3 0.2 1.1e-16 60.6 0.2 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EKX35788.1 - 1e-08 35.0 0.3 1.3e-08 34.6 0.3 1.2 1 0 0 1 1 1 1 MafB19-like deaminase OTT_1508_deam PF14441.6 EKX35788.1 - 0.039 14.0 0.0 0.09 12.8 0.0 1.6 1 0 0 1 1 1 0 OTT_1508-like deaminase Oxysterol_BP PF01237.18 EKX35788.1 - 4.3 6.1 7.1 5.7 5.7 7.1 1.1 1 0 0 1 1 1 0 Oxysterol-binding protein MORN PF02493.20 EKX35789.1 - 5.4e-22 76.3 21.5 2.5e-09 36.5 1.2 4.0 4 0 0 4 4 4 4 MORN repeat Peptidase_M66 PF10462.9 EKX35789.1 - 0.089 11.7 2.7 0.095 11.6 2.7 1.2 1 0 0 1 1 1 0 Peptidase M66 MORN_2 PF07661.13 EKX35789.1 - 3.9 8.0 6.6 13 6.4 0.1 3.4 3 1 0 3 3 3 0 MORN repeat variant HHH PF00633.23 EKX35790.1 - 0.0037 17.1 0.0 0.0085 15.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Transposase_20 PF02371.16 EKX35790.1 - 0.0073 16.6 0.0 0.023 15.0 0.0 1.8 2 0 0 2 2 2 1 Transposase IS116/IS110/IS902 family HHH_5 PF14520.6 EKX35790.1 - 0.037 14.6 0.0 0.086 13.5 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain LRR_8 PF13855.6 EKX35792.1 - 1.2e-34 117.9 46.3 5.5e-06 26.1 0.3 10.4 6 4 5 11 11 11 10 Leucine rich repeat LRR_4 PF12799.7 EKX35792.1 - 1.9e-29 101.2 52.8 0.00015 22.1 5.0 12.3 8 2 4 13 13 13 11 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EKX35792.1 - 2.2e-09 36.6 57.9 0.043 13.9 0.1 14.4 15 0 0 15 15 15 6 Leucine Rich repeat LRR_9 PF14580.6 EKX35792.1 - 1.6e-05 24.5 15.5 0.00054 19.5 1.2 5.0 2 2 2 6 6 6 3 Leucine-rich repeat LRR_1 PF00560.33 EKX35792.1 - 3.4e-05 23.8 49.5 4.4 8.2 0.3 14.8 14 3 0 14 14 14 4 Leucine Rich Repeat LRR_5 PF13306.6 EKX35792.1 - 0.0063 16.5 0.4 7 6.6 0.0 3.8 3 1 2 5 5 5 1 BspA type Leucine rich repeat region (6 copies) DnaJ PF00226.31 EKX35793.1 - 0.013 15.6 0.1 0.037 14.1 0.1 1.8 1 0 0 1 1 1 0 DnaJ domain DUF3958 PF13125.6 EKX35793.1 - 3.4 7.9 15.4 0.088 13.0 3.6 3.6 4 1 1 5 5 5 0 Protein of unknown function (DUF3958) WW PF00397.26 EKX35794.1 - 2.3e-07 30.8 0.0 5.4e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 WW domain NOA36 PF06524.12 EKX35794.1 - 0.65 9.3 8.4 1.6 8.0 8.4 1.6 1 0 0 1 1 1 0 NOA36 protein T2SSF PF00482.23 EKX35794.1 - 0.99 9.4 8.2 6.2 6.8 0.3 3.2 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F Sigma_1s PF02454.16 EKX35794.1 - 2.2 8.3 6.5 0.35 10.8 2.1 1.9 2 0 0 2 2 2 0 Sigma 1s protein PP2C PF00481.21 EKX35795.1 - 2.3e-42 145.4 0.1 2.6e-42 145.2 0.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EKX35795.1 - 1.4e-06 28.1 0.1 2e-06 27.6 0.1 1.3 1 1 0 1 1 1 1 Protein phosphatase 2C TPP_enzyme_C PF02775.21 EKX35795.1 - 0.053 13.3 0.0 0.29 10.9 0.0 1.9 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain WD40 PF00400.32 EKX35796.1 - 1e-11 45.1 17.3 1.5 9.9 0.1 12.7 13 0 0 13 13 13 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX35796.1 - 7.2e-06 26.2 0.4 7.6 6.9 0.0 7.9 7 3 1 8 8 8 1 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_7 PF13499.6 EKX35796.1 - 2.4e-05 24.7 4.8 3.6 8.1 0.1 4.9 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 EKX35796.1 - 3.3e-05 23.5 1.0 0.34 11.0 0.0 4.5 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 EKX35796.1 - 0.00045 19.6 0.0 0.3 10.7 0.0 3.8 3 0 0 3 3 3 1 EF hand PDZ_4 PF17816.1 EKX35796.1 - 0.11 12.9 0.0 0.67 10.4 0.0 2.4 2 0 0 2 2 2 0 PDZ domain GST_N_3 PF13417.6 EKX35797.1 - 0.019 15.4 0.1 0.072 13.5 0.1 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EKX35797.1 - 0.1 13.0 0.0 0.61 10.5 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 EKX35797.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.6 1 1 0 1 1 1 0 Glutaredoxin SIR2 PF02146.17 EKX35798.1 - 3.5e-45 154.1 0.0 5.8e-45 153.4 0.0 1.4 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EKX35798.1 - 0.051 13.3 0.0 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain zf-TFIIB PF13453.6 EKX35798.1 - 0.054 12.8 2.1 0.13 11.6 0.1 2.5 3 0 0 3 3 3 0 Transcription factor zinc-finger Zn_ribbon_recom PF13408.6 EKX35798.1 - 0.11 13.0 0.5 1.9 9.0 0.0 2.6 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DNA_RNApol_7kD PF03604.13 EKX35798.1 - 0.57 9.9 6.0 0.35 10.6 0.2 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit GST_N PF02798.20 EKX35799.1 - 0.018 15.4 0.0 0.023 15.0 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 EKX35799.1 - 0.057 13.6 0.0 0.085 13.1 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin GST_N_3 PF13417.6 EKX35799.1 - 0.12 12.8 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Proteasome PF00227.26 EKX35800.1 - 1.9e-17 63.4 2.3 1.1e-16 60.9 2.3 1.9 1 1 0 1 1 1 1 Proteasome subunit Alpha-amylase PF00128.24 EKX35801.1 - 1.2e-13 51.4 0.0 4.4e-11 42.9 0.0 2.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain NAD_binding_8 PF13450.6 EKX35801.1 - 0.078 13.2 0.2 0.24 11.7 0.2 1.8 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DNA_pol_A_exo1 PF01612.20 EKX35802.1 - 1.6e-07 31.2 0.0 1e-06 28.6 0.0 2.0 1 1 0 1 1 1 1 3'-5' exonuclease Msap1 PF17077.5 EKX35802.1 - 0.086 12.0 0.1 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 Mitotic spindle associated protein SHE1 Pkinase PF00069.25 EKX35803.1 - 2e-16 60.1 0.0 1.7e-15 57.1 0.0 1.9 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX35803.1 - 7.9e-08 31.9 0.0 3.8e-07 29.7 0.0 1.7 1 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EKX35803.1 - 0.065 13.2 0.0 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EKX35803.1 - 0.077 12.3 0.0 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like SVIP PF15811.5 EKX35803.1 - 0.12 12.9 0.1 0.18 12.2 0.1 1.3 1 0 0 1 1 1 0 Small VCP/p97-interacting protein Pkinase_fungal PF17667.1 EKX35803.1 - 0.14 10.9 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 EKX35804.1 - 2.3e-28 99.3 0.0 2.6e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX35804.1 - 3.2e-16 59.4 0.0 3.9e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX35804.1 - 6.3e-05 23.0 0.1 0.0019 18.2 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX35804.1 - 0.0004 19.8 0.0 0.00066 19.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EKX35804.1 - 0.0025 17.2 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EKX35804.1 - 0.0058 15.7 0.0 0.032 13.3 0.0 1.8 2 0 0 2 2 2 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 EKX35804.1 - 0.013 14.3 0.1 0.13 11.0 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase FTA2 PF13095.6 EKX35804.1 - 0.025 14.2 0.1 0.62 9.6 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EKX35804.1 - 0.19 10.7 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain adh_short PF00106.25 EKX35805.1 - 1.5e-41 142.1 3.9 1.9e-41 141.6 3.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EKX35805.1 - 2.6e-26 92.6 0.5 3.6e-26 92.2 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX35805.1 - 0.0014 18.5 0.7 0.0027 17.6 0.7 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EKX35805.1 - 0.0025 17.8 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 EKX35805.1 - 0.025 14.0 0.0 0.57 9.5 0.0 2.1 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) F420_oxidored PF03807.17 EKX35805.1 - 0.032 14.8 0.2 0.069 13.7 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N PF00107.26 EKX35805.1 - 0.053 13.5 0.6 5.2 7.1 0.1 3.3 2 1 1 3 3 3 0 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 EKX35805.1 - 0.064 13.5 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Glucodextran_C PF09985.9 EKX35805.1 - 0.14 11.6 0.1 5.9 6.3 0.0 2.2 2 0 0 2 2 2 0 C-terminal binding-module, SLH-like, of glucodextranase zf-RING_2 PF13639.6 EKX35806.1 - 2.2e-14 53.5 11.9 2.6e-14 53.2 11.9 1.1 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EKX35806.1 - 4.4e-09 36.5 11.3 7.3e-09 35.8 11.3 1.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EKX35806.1 - 3.3e-08 33.4 11.2 4.1e-08 33.0 11.2 1.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EKX35806.1 - 5.7e-08 32.5 12.1 7.3e-08 32.2 12.1 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EKX35806.1 - 5.8e-08 32.4 12.0 7.6e-08 32.1 12.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EKX35806.1 - 2.2e-07 30.5 9.5 2.2e-07 30.5 9.5 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EKX35806.1 - 6.9e-07 29.0 9.9 3.7e-06 26.7 9.6 1.9 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EKX35806.1 - 1.2e-05 24.8 6.7 1.7e-05 24.4 6.7 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 EKX35806.1 - 1.3e-05 25.2 6.8 1.3e-05 25.2 6.8 1.6 1 1 1 2 2 2 1 RING-type zinc-finger RINGv PF12906.7 EKX35806.1 - 3.3e-05 23.9 6.2 8.6e-05 22.6 6.2 1.7 1 1 0 1 1 1 1 RING-variant domain Prok-RING_4 PF14447.6 EKX35806.1 - 3.5e-05 23.6 8.0 7.8e-05 22.5 8.1 1.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EKX35806.1 - 8.8e-05 22.5 6.1 0.0009 19.2 6.1 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 EKX35806.1 - 0.095 12.9 9.7 0.42 10.8 9.7 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 EKX35806.1 - 4.9 7.0 13.2 17 5.3 2.2 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain NUDIX PF00293.28 EKX35807.1 - 3.1e-18 66.1 0.1 3.7e-18 65.8 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EKX35807.1 - 2.2e-12 46.9 0.0 5.2e-12 45.7 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 EKX35807.1 - 0.0041 16.7 0.0 0.0047 16.5 0.0 1.2 1 0 0 1 1 1 1 Nucleotide hydrolase Lig_chan PF00060.26 EKX35809.1 - 7.2e-14 51.9 0.0 1.5e-13 50.9 0.0 1.6 1 1 0 1 1 1 1 Ligand-gated ion channel Defensin_2 PF01097.18 EKX35809.1 - 0.74 9.8 3.9 1.4 8.9 3.9 1.4 1 0 0 1 1 1 0 Arthropod defensin Alpha_kinase PF02816.18 EKX35810.1 - 6.8e-12 45.9 0.2 6.8e-12 45.9 0.2 1.7 2 0 0 2 2 2 1 Alpha-kinase family Spc7 PF08317.11 EKX35811.1 - 0.0023 16.8 17.3 0.0023 16.8 17.3 3.5 1 1 2 3 3 3 2 Spc7 kinetochore protein DUF1664 PF07889.12 EKX35811.1 - 0.012 15.6 4.5 0.012 15.6 4.5 5.2 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Lambda_tail_I PF06805.12 EKX35811.1 - 0.072 13.4 0.3 2 8.8 0.1 2.5 2 0 0 2 2 2 0 Bacteriophage lambda tail assembly protein I dCache_1 PF02743.18 EKX35811.1 - 0.13 12.1 1.1 0.21 11.3 1.1 1.4 1 0 0 1 1 1 0 Cache domain Rootletin PF15035.6 EKX35811.1 - 0.73 9.8 56.7 5 7.1 29.6 3.8 1 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion Taxilin PF09728.9 EKX35811.1 - 0.85 8.7 61.2 1.1 8.3 59.9 1.8 1 1 1 2 2 1 0 Myosin-like coiled-coil protein Fez1 PF06818.15 EKX35811.1 - 1.6 9.2 61.7 0.77 10.2 12.2 3.9 1 1 3 4 4 4 0 Fez1 DUF3138 PF11336.8 EKX35811.1 - 1.6 7.2 6.8 0.19 10.3 1.4 1.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3138) IFT57 PF10498.9 EKX35811.1 - 2.4 7.1 55.6 3.8 6.4 19.5 3.8 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 Atg14 PF10186.9 EKX35811.1 - 2.7 7.0 53.7 0.64 9.0 14.9 3.2 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 EKX35811.1 - 2.9 8.0 66.8 0.044 13.8 21.4 4.1 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Filament PF00038.21 EKX35811.1 - 8 5.9 60.0 2.8 7.5 22.1 3.1 1 1 2 3 3 3 0 Intermediate filament protein PI3Ka PF00613.20 EKX35812.1 - 8.9e-20 70.9 0.3 9.1e-10 38.2 0.0 2.7 3 0 0 3 3 3 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EKX35812.1 - 0.0027 17.5 0.1 0.11 12.3 0.0 2.2 1 1 1 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Kinesin PF00225.23 EKX35813.1 - 1.7e-91 306.6 0.2 2.7e-91 306.0 0.2 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX35813.1 - 2.1e-36 125.1 0.0 1.3e-25 90.0 0.0 2.5 2 0 0 2 2 2 2 Microtubule binding YkyA PF10368.9 EKX35813.1 - 0.01 15.5 10.4 0.021 14.5 10.4 1.4 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Spc7 PF08317.11 EKX35813.1 - 0.013 14.4 5.0 0.022 13.7 5.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-Q PF13094.6 EKX35813.1 - 0.048 13.9 10.0 0.2 11.9 10.1 2.0 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit AAA_23 PF13476.6 EKX35813.1 - 7.3 7.0 11.6 3.3 8.2 5.6 2.6 3 0 0 3 3 3 0 AAA domain Ephrin_rec_like PF07699.13 EKX35814.1 - 1.2e-40 137.0 80.8 1.8e-11 43.6 6.3 8.5 6 1 3 9 9 9 8 Putative ephrin-receptor like NCD3G PF07562.14 EKX35814.1 - 1.9e-10 40.5 67.9 0.00088 19.2 1.8 8.2 5 2 3 8 8 8 7 Nine Cysteines Domain of family 3 GPCR Phage_tail_NK PF16532.5 EKX35814.1 - 0.0069 16.0 0.4 1.6 8.3 0.2 2.4 2 0 0 2 2 2 2 Sf6-type phage tail needle knob or tip of some Caudovirales YL1_C PF08265.11 EKX35814.1 - 0.015 15.0 0.2 9.5 6.1 0.0 2.8 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain TNFR_c6 PF00020.18 EKX35814.1 - 0.092 13.2 66.5 0.95 9.9 0.5 9.7 5 3 5 10 10 10 0 TNFR/NGFR cysteine-rich region CCDC106 PF15794.5 EKX35815.1 - 0.0007 19.4 9.9 0.0007 19.4 9.9 4.0 3 1 0 3 3 2 2 Coiled-coil domain-containing protein 106 Fez1 PF06818.15 EKX35815.1 - 0.0077 16.7 83.7 0.74 10.2 7.8 5.1 1 1 3 4 4 4 3 Fez1 HALZ PF02183.18 EKX35815.1 - 0.015 15.5 0.1 0.015 15.5 0.1 8.5 10 1 1 11 11 9 0 Homeobox associated leucine zipper DUF641 PF04859.12 EKX35815.1 - 0.028 14.7 1.2 0.028 14.7 1.2 7.2 3 2 6 9 9 8 0 Plant protein of unknown function (DUF641) DUF5595 PF18077.1 EKX35815.1 - 0.081 13.0 0.3 0.081 13.0 0.3 7.4 8 2 2 10 10 10 0 Domain of unknown function (DUF5595) MHB PF16525.5 EKX35815.1 - 0.22 11.8 1.2 2.1 8.6 0.0 3.2 4 0 0 4 4 4 0 Haemophore, haem-binding DUF2353 PF09789.9 EKX35815.1 - 0.3 10.4 69.7 2.2 7.6 20.9 5.2 1 1 1 4 4 4 0 Uncharacterized coiled-coil protein (DUF2353) CENP-F_leu_zip PF10473.9 EKX35815.1 - 0.34 10.9 82.3 0.14 12.2 3.1 6.4 1 1 4 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 EKX35815.1 - 0.56 9.7 75.3 0.24 10.9 7.0 6.0 1 1 6 7 7 7 0 Intermediate filament protein DUF4250 PF14056.6 EKX35815.1 - 1.2 9.1 4.1 3 7.9 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) GAS PF13851.6 EKX35815.1 - 1.9 7.8 81.0 0.014 14.8 5.6 6.3 1 1 4 5 5 5 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.8 EKX35815.1 - 1.9 5.9 77.0 0.016 12.8 8.6 3.4 1 1 0 3 3 3 0 Protein of unknown function (DUF3584) Golgin_A5 PF09787.9 EKX35815.1 - 3 7.2 77.6 0.57 9.6 19.0 4.6 1 1 3 5 5 5 0 Golgin subfamily A member 5 Snapin_Pallidin PF14712.6 EKX35815.1 - 8.7 6.8 49.7 0.13 12.7 3.0 8.1 4 3 5 10 10 10 0 Snapin/Pallidin Ion_trans PF00520.31 EKX35816.1 - 3.7e-21 75.5 11.6 5.5e-21 74.9 11.6 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 EKX35816.1 - 2.4e-13 50.0 0.0 8.2e-13 48.3 0.0 2.0 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EKX35816.1 - 2.7e-12 46.5 2.6 2.7e-12 46.5 2.6 1.9 2 0 0 2 2 2 1 Ion channel MORN PF02493.20 EKX35817.1 - 4.7e-09 35.6 20.1 0.0024 17.6 0.0 4.9 5 0 0 5 5 5 4 MORN repeat Hrs_helical PF12210.8 EKX35817.1 - 1.4 9.5 0.0 1.4 9.5 0.0 3.7 4 0 0 4 4 4 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Borrelia_P83 PF05262.11 EKX35817.1 - 6.3 5.2 17.1 9.7 4.6 17.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein UPF0020 PF01170.18 EKX35818.1 - 9.5e-48 162.5 0.0 1.7e-47 161.7 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 THUMP PF02926.17 EKX35818.1 - 3e-05 24.1 0.0 6.7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 THUMP domain MTS PF05175.14 EKX35818.1 - 0.00028 20.5 0.0 0.00053 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain N6_Mtase PF02384.16 EKX35818.1 - 0.00032 20.1 0.0 0.002 17.5 0.0 1.9 1 1 0 1 1 1 1 N-6 DNA Methylase Methyltransf_31 PF13847.6 EKX35818.1 - 0.0011 18.8 0.0 8.5 6.2 0.0 3.7 3 1 0 3 3 3 1 Methyltransferase domain N6_N4_Mtase PF01555.18 EKX35818.1 - 0.0027 17.4 0.0 0.029 14.1 0.0 2.1 2 0 0 2 2 2 1 DNA methylase Methyltransf_25 PF13649.6 EKX35818.1 - 0.0044 17.7 0.0 0.022 15.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EKX35818.1 - 0.019 14.6 0.0 2.2 7.9 0.0 2.6 3 0 0 3 3 3 0 Conserved hypothetical protein 95 AviRa PF11599.8 EKX35818.1 - 0.047 13.1 0.0 0.31 10.5 0.0 2.3 1 1 0 1 1 1 0 RRNA methyltransferase AviRa CS PF04969.16 EKX35819.1 - 2.9e-05 25.0 0.3 0.00011 23.2 0.2 1.9 2 0 0 2 2 2 1 CS domain DUF3710 PF12502.8 EKX35819.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3710) BHD_2 PF10404.9 EKX35820.1 - 0.066 14.2 3.0 0.084 13.8 1.3 2.1 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 2 DUF4406 PF14359.6 EKX35820.1 - 0.066 13.7 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4406) DUF2937 PF11157.8 EKX35820.1 - 0.18 11.5 3.0 0.8 9.4 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) DUF3810 PF12725.7 EKX35820.1 - 2.3 7.5 3.9 1.2 8.4 1.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3810) Pannexin_like PF12534.8 EKX35820.1 - 2.8 6.9 7.9 7.5 5.5 7.9 1.7 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Laminin_G_3 PF13385.6 EKX35821.1 - 2.8e-20 73.0 0.1 4.7e-20 72.3 0.1 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Sialidase PF02973.16 EKX35821.1 - 0.023 14.2 0.0 0.06 12.8 0.0 1.8 2 1 0 2 2 2 0 Sialidase, N-terminal domain LysM PF01476.20 EKX35822.1 - 1.5e-15 56.9 0.0 2.8e-06 27.3 0.0 2.5 2 0 0 2 2 2 2 LysM domain LysM PF01476.20 EKX35823.1 - 0.025 14.6 0.0 0.26 11.4 0.0 2.1 2 0 0 2 2 2 0 LysM domain Zip PF02535.22 EKX35824.1 - 1.7e-39 136.0 16.3 5e-29 101.6 8.5 3.0 2 1 1 3 3 3 2 ZIP Zinc transporter PBP1_TM PF14812.6 EKX35824.1 - 0.021 15.2 2.3 0.041 14.3 0.9 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fumarate_red_D PF02313.17 EKX35824.1 - 0.03 14.4 0.5 0.03 14.4 0.5 2.3 2 0 0 2 2 2 0 Fumarate reductase subunit D LRR_8 PF13855.6 EKX35825.1 - 8.5e-26 89.5 10.7 4.3e-09 36.0 0.3 4.4 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EKX35825.1 - 1.2e-19 70.0 18.1 6.2e-06 26.5 0.3 5.7 1 1 9 10 10 10 10 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX35825.1 - 2.7e-16 59.6 2.5 1.1e-09 38.0 0.2 2.8 2 1 1 3 3 3 2 Leucine-rich repeat RRM_1 PF00076.22 EKX35825.1 - 1.2e-11 44.3 0.3 3.9e-10 39.4 0.0 3.2 2 2 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRR_6 PF13516.6 EKX35825.1 - 4.2e-07 29.5 15.1 5 7.4 0.1 7.5 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 EKX35825.1 - 4.6e-05 23.4 16.0 17 6.5 0.2 8.1 8 1 0 8 8 8 1 Leucine Rich Repeat RSS_P20 PF11757.8 EKX35825.1 - 0.07 13.6 1.7 2.6 8.5 0.0 2.7 3 0 0 3 3 3 0 Suppressor of RNA silencing P21-like N-terminal domain Pkinase_Tyr PF07714.17 EKX35827.1 - 1.9e-33 115.8 0.0 2.2e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX35827.1 - 5.5e-29 101.3 0.0 6.3e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EKX35827.1 - 5.4e-06 25.4 0.2 7.5e-06 25.0 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EKX35827.1 - 2.8e-05 23.6 0.0 4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EKX35827.1 - 0.00016 21.3 0.0 0.00024 20.8 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EKX35827.1 - 0.00022 20.6 0.0 0.00031 20.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EKX35827.1 - 0.0014 17.6 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EKX35827.1 - 0.0034 17.3 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FH2 PF02181.23 EKX35828.1 - 5.5e-45 154.1 0.1 6.5e-45 153.8 0.1 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain Pox_Ag35 PF03286.14 EKX35829.1 - 0.9 9.3 0.0 0.9 9.3 0.0 2.0 1 1 1 2 2 2 0 Pox virus Ag35 surface protein EF-hand_1 PF00036.32 EKX35830.1 - 4.8e-05 22.6 1.0 0.00026 20.3 0.1 2.7 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 EKX35830.1 - 0.00024 20.8 1.9 0.00052 19.7 0.7 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 EKX35830.1 - 0.0008 18.8 0.6 0.0036 16.7 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EKX35830.1 - 0.0087 16.5 2.4 0.0087 16.5 2.4 2.5 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_9 PF14658.6 EKX35830.1 - 0.018 15.3 0.0 0.74 10.2 0.0 2.5 2 1 0 2 2 2 0 EF-hand domain Caleosin PF05042.13 EKX35830.1 - 0.066 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Caleosin related protein Intein_splicing PF14890.6 EKX35830.1 - 3.9 7.4 4.5 6.5 6.7 4.1 1.5 1 1 0 1 1 1 0 Intein splicing domain PH PF00169.29 EKX35831.1 - 8.8e-06 26.2 0.4 2.8e-05 24.6 0.4 1.8 1 1 0 1 1 1 1 PH domain PH_8 PF15409.6 EKX35831.1 - 0.033 14.5 0.0 0.11 12.8 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain PH_11 PF15413.6 EKX35831.1 - 0.23 11.9 2.1 7.9 7.0 1.5 2.6 1 1 0 1 1 1 0 Pleckstrin homology domain DEAD PF00270.29 EKX35832.1 - 5.2e-32 111.0 0.0 2.9e-31 108.6 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EKX35832.1 - 3.2e-08 33.8 0.0 7.5e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EKX35832.1 - 1.7e-07 31.6 0.0 4.6e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SSE PF00437.20 EKX35832.1 - 0.026 13.6 0.2 8.1 5.4 0.0 2.6 2 1 1 3 3 3 0 Type II/IV secretion system protein AAA_19 PF13245.6 EKX35832.1 - 0.034 14.5 0.0 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain NOA36 PF06524.12 EKX35832.1 - 0.27 10.5 1.9 0.42 9.9 1.9 1.2 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 EKX35832.1 - 0.59 10.4 11.4 1.4 9.1 11.4 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 LysM PF01476.20 EKX35833.1 - 0.025 14.6 0.0 0.26 11.4 0.0 2.1 2 0 0 2 2 2 0 LysM domain LysM PF01476.20 EKX35834.1 - 2.2e-16 59.6 0.0 9.3e-07 28.8 0.0 2.3 2 0 0 2 2 2 2 LysM domain CBM_20 PF00686.19 EKX35835.1 - 2.1e-14 53.2 0.0 3.2e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Starch binding domain DLH PF01738.18 EKX35836.1 - 8.8e-17 61.4 0.0 1.2e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 EKX35836.1 - 0.13 11.5 0.1 14 4.9 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 HSP33 PF01430.19 EKX35838.1 - 3.5e-44 151.2 0.0 4.4e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 Hsp33 protein DUF4094 PF13334.6 EKX35839.1 - 0.12 12.8 0.3 0.34 11.3 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DUF4094 PF13334.6 EKX35840.1 - 0.0017 18.7 0.3 0.0043 17.4 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4094) S_4TM PF18159.1 EKX35840.1 - 0.024 13.9 1.9 0.036 13.4 1.9 1.4 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain Helicase_C PF00271.31 EKX35841.1 - 4.1e-19 69.0 0.0 1.1e-18 67.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EKX35841.1 - 1.5e-16 60.6 0.0 3.8e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 EKX35841.1 - 5e-08 33.6 0.8 1.9e-07 31.7 0.8 2.1 1 0 0 1 1 1 1 RecQ zinc-binding HRDC PF00570.23 EKX35841.1 - 5.6e-05 23.0 0.0 0.00016 21.6 0.0 1.7 1 0 0 1 1 1 1 HRDC domain HTH_40 PF14493.6 EKX35841.1 - 0.021 15.3 0.1 0.1 13.1 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Prefoldin_2 PF01920.20 EKX35842.1 - 4.6e-07 29.8 10.1 3e-05 23.9 2.1 2.1 2 0 0 2 2 2 2 Prefoldin subunit Fez1 PF06818.15 EKX35842.1 - 0.014 15.8 4.0 2 8.8 0.3 2.1 2 0 0 2 2 2 0 Fez1 CCDC144C PF14915.6 EKX35842.1 - 0.021 13.9 1.7 0.021 13.9 1.7 1.9 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region TPR_MLP1_2 PF07926.12 EKX35842.1 - 0.025 14.6 1.3 0.025 14.6 1.3 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CC2-LZ PF16516.5 EKX35842.1 - 0.21 12.0 6.4 1.1 9.6 1.4 2.1 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator ZapB PF06005.12 EKX35842.1 - 0.25 11.8 7.7 0.15 12.5 1.6 2.1 2 0 0 2 2 2 0 Cell division protein ZapB Seryl_tRNA_N PF02403.22 EKX35842.1 - 0.36 11.1 5.2 0.49 10.6 1.0 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PRKG1_interact PF15898.5 EKX35842.1 - 0.44 11.5 5.8 2.1 9.3 1.1 2.1 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Spc24 PF08286.11 EKX35842.1 - 0.83 9.9 4.3 1.3 9.3 0.7 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 HAUS4 PF14735.6 EKX35843.1 - 4e-23 82.3 4.9 4.4e-23 82.2 4.9 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 4 VPS38 PF17649.1 EKX35843.1 - 0.0037 16.2 1.1 0.0041 16.1 1.1 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting 38 GAS PF13851.6 EKX35843.1 - 0.015 14.6 5.5 0.02 14.2 5.5 1.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.22 EKX35843.1 - 0.019 15.2 4.6 0.025 14.8 4.6 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF2203 PF09969.9 EKX35843.1 - 0.2 12.4 2.5 0.26 12.0 2.1 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) HIP1_clath_bdg PF16515.5 EKX35843.1 - 0.23 12.1 7.5 0.17 12.5 5.7 1.6 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CP12 PF02672.15 EKX35843.1 - 0.59 10.9 3.7 1.7 9.5 1.6 2.4 1 1 2 3 3 3 0 CP12 domain DUF4600 PF15372.6 EKX35843.1 - 1.3 9.5 7.4 5.4 7.5 0.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) THOC7 PF05615.13 EKX35843.1 - 1.3 9.3 8.9 17 5.7 8.9 2.1 1 1 0 1 1 1 0 Tho complex subunit 7 CCDC-167 PF15188.6 EKX35843.1 - 3.2 8.1 7.0 45 4.5 7.0 2.2 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 zf-RING_2 PF13639.6 EKX35845.1 - 5.9e-09 36.1 19.3 1.3e-08 35.1 19.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX35845.1 - 1.3e-06 28.1 19.5 2.9e-06 27.0 19.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX35845.1 - 8.2e-05 22.8 21.3 0.001 19.3 21.3 2.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EKX35845.1 - 0.0086 15.8 9.8 0.0086 15.8 9.8 2.3 2 1 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 EKX35845.1 - 0.012 15.5 23.8 0.024 14.5 23.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX35845.1 - 0.018 15.1 9.8 0.018 15.1 9.8 1.6 1 1 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 EKX35845.1 - 0.093 12.8 13.5 0.27 11.3 13.5 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EKX35845.1 - 2.2 8.0 21.7 4.6 6.9 21.7 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 EKX35845.1 - 2.7 7.9 23.3 4.7 7.1 23.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.7 EKX35847.1 - 4.1e-09 36.9 0.0 1.2e-08 35.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX35847.1 - 5.6e-05 23.2 0.1 0.0055 17.1 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EKX35847.1 - 5.9e-05 23.3 0.7 0.0022 18.4 0.3 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EKX35847.1 - 0.00014 22.4 0.1 0.00051 20.6 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX35847.1 - 0.001 19.4 0.1 0.0022 18.2 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Peptidase_M16_C PF05193.21 EKX35848.1 - 0.0014 18.7 0.3 0.011 15.7 0.0 2.4 2 0 0 2 2 2 1 Peptidase M16 inactive domain TT_ORF1 PF02956.14 EKX35848.1 - 0.013 14.2 3.4 0.026 13.2 3.4 1.4 1 0 0 1 1 1 0 TT viral orf 1 RAP PF08373.10 EKX35849.1 - 2.2e-19 69.3 0.0 3.4e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 RAP domain MTES_1575 PF18741.1 EKX35849.1 - 1.8e-05 24.8 0.0 8e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 REase_MTES_1575 SR-25 PF10500.9 EKX35849.1 - 0.002 17.8 9.0 0.0021 17.7 9.0 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 EKX35849.1 - 0.0053 17.0 10.8 0.0076 16.5 10.8 1.3 1 0 0 1 1 1 1 Early growth response N-terminal domain Herpes_pp85 PF04637.12 EKX35849.1 - 0.0082 14.6 5.4 0.0097 14.4 5.4 1.0 1 0 0 1 1 1 1 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) DUF3677 PF12432.8 EKX35849.1 - 0.095 13.0 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3677) bZIP_C PF12498.8 EKX35849.1 - 0.16 12.9 0.9 0.22 12.5 0.9 1.2 1 0 0 1 1 1 0 Basic leucine-zipper C terminal RsbRD_N PF14361.6 EKX35850.1 - 0.023 15.4 0.7 21 5.8 0.0 4.4 4 0 0 4 4 4 0 RsbT co-antagonist protein rsbRD N-terminal domain MarR_2 PF12802.7 EKX35850.1 - 0.097 12.6 0.0 13 5.7 0.0 3.6 3 1 0 3 3 3 0 MarR family DUF1601 PF07671.11 EKX35850.1 - 5.2 7.0 12.5 46 4.0 0.1 5.6 6 0 0 6 6 6 0 Protein of unknown function (DUF1601) LysM PF01476.20 EKX35851.1 - 0.0025 17.8 0.0 0.0074 16.3 0.0 1.7 1 0 0 1 1 1 1 LysM domain CENP-H PF05837.12 EKX35853.1 - 0.0014 19.0 4.4 0.0014 19.0 4.4 11.7 3 3 9 12 12 12 1 Centromere protein H (CENP-H) ATG16 PF08614.11 EKX35853.1 - 0.0018 18.6 21.3 0.0018 18.6 21.3 9.0 3 3 5 8 8 8 2 Autophagy protein 16 (ATG16) PI_PP_I PF18363.1 EKX35853.1 - 0.46 10.7 15.2 0.049 13.8 1.0 4.9 4 1 0 5 5 5 0 Phosphoinositide phosphatase insertion domain DUF5345 PF17280.2 EKX35853.1 - 5.3 7.1 6.4 5.2 7.1 0.4 4.4 2 0 0 2 2 2 0 Family of unknown function (DUF5345) DnaJ PF00226.31 EKX35854.1 - 7.4e-20 70.9 0.1 1.1e-19 70.3 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain DUF4205 PF13898.6 EKX35855.1 - 2.2e-32 112.4 0.0 7.3e-31 107.4 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4205) PH PF00169.29 EKX35855.1 - 1.8e-10 41.3 0.1 4.3e-09 36.8 0.0 2.9 2 1 0 2 2 2 1 PH domain LRR_6 PF13516.6 EKX35855.1 - 3.9e-08 32.7 8.5 0.0022 17.9 0.5 3.7 3 0 0 3 3 3 2 Leucine Rich repeat PH_11 PF15413.6 EKX35855.1 - 0.00026 21.4 0.0 0.083 13.3 0.0 2.6 2 0 0 2 2 2 2 Pleckstrin homology domain LRR_4 PF12799.7 EKX35855.1 - 0.034 14.6 1.7 0.061 13.8 0.3 2.2 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) TPR_MLP1_2 PF07926.12 EKX35856.1 - 0.012 15.7 1.4 0.23 11.6 0.0 2.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein PGM_PMM_II PF02879.16 EKX35856.1 - 0.033 14.8 0.0 0.1 13.2 0.0 1.8 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DivIVA PF05103.13 EKX35856.1 - 0.25 11.4 2.9 8.7 6.4 0.3 2.7 2 0 0 2 2 2 0 DivIVA protein LNS2 PF08235.13 EKX35857.1 - 3.5e-41 141.2 0.0 6.5e-40 137.0 0.0 2.3 1 1 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EKX35857.1 - 2.5e-11 43.4 0.2 2.8e-10 40.1 0.0 2.3 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 EKX35857.1 - 0.082 12.5 0.1 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF755 PF05501.11 EKX35858.1 - 0.065 13.5 2.0 0.12 12.7 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Pox_A_type_inc PF04508.12 EKX35859.1 - 0.14 12.0 0.1 0.14 12.0 0.1 3.0 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Baculo_PEP_C PF04513.12 EKX35859.1 - 2.8 8.0 18.5 1.4 8.9 4.5 3.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus HalX PF08663.10 EKX35859.1 - 4.1 7.8 16.8 0.44 10.9 3.1 4.0 3 1 0 3 3 3 0 HalX domain Prominin PF05478.11 EKX35859.1 - 7.6 4.3 24.2 3.7 5.4 5.6 1.9 1 1 0 2 2 2 0 Prominin POT1 PF02765.17 EKX35860.1 - 3.9e-18 65.7 0.0 9e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.25 EKX35860.1 - 0.0068 16.4 0.0 0.74 9.8 0.0 2.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain POT1PC PF16686.5 EKX35860.1 - 0.0087 15.9 0.2 0.21 11.5 0.0 2.8 3 1 1 4 4 4 1 ssDNA-binding domain of telomere protection protein DUF4251 PF14059.6 EKX35860.1 - 0.1 12.5 0.0 0.84 9.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4251) Pkinase PF00069.25 EKX35861.1 - 6.3e-13 48.7 0.0 1e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX35861.1 - 6.7e-08 32.1 0.0 8.8e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase p450 PF00067.22 EKX35862.1 - 3.8e-95 319.4 0.0 4.4e-95 319.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FapA PF03961.13 EKX35865.1 - 0.0078 14.9 11.4 0.042 12.5 6.4 2.1 2 0 0 2 2 2 2 Flagellar Assembly Protein A Baculo_PEP_C PF04513.12 EKX35865.1 - 0.01 15.9 5.4 1.9 8.6 0.0 3.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4515 PF14988.6 EKX35865.1 - 0.034 14.0 0.3 0.034 14.0 0.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4515) TraC PF07820.12 EKX35865.1 - 0.07 13.5 3.6 0.11 12.9 1.0 2.4 2 0 0 2 2 2 0 TraC-like protein MCU PF04678.13 EKX35865.1 - 0.18 11.9 0.2 0.18 11.9 0.2 2.7 2 1 0 2 2 2 0 Mitochondrial calcium uniporter AMP-binding_C_2 PF14535.6 EKX35865.1 - 0.28 11.5 3.4 0.16 12.3 0.3 2.2 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain OmpH PF03938.14 EKX35865.1 - 0.33 11.3 15.1 0.41 11.0 5.5 2.5 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Syntaxin-6_N PF09177.11 EKX35865.1 - 0.8 10.3 14.6 4 8.1 1.2 3.6 2 2 1 3 3 3 0 Syntaxin 6, N-terminal GTP-bdg_M PF16360.5 EKX35865.1 - 9.7 6.9 9.2 0.91 10.2 3.4 2.3 2 1 0 2 2 2 0 GTP-binding GTPase Middle Region DivIC PF04977.15 EKX35867.1 - 0.002 17.8 3.8 0.004 16.9 3.4 1.7 1 1 0 1 1 1 1 Septum formation initiator DUF603 PF04645.12 EKX35867.1 - 0.0058 16.3 1.5 0.015 15.0 1.5 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF603 Choline_kinase PF01633.20 EKX35867.1 - 0.013 15.1 1.2 0.018 14.6 1.2 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase UPF0242 PF06785.11 EKX35867.1 - 0.11 12.5 6.6 0.18 11.9 6.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TMF_TATA_bd PF12325.8 EKX35867.1 - 0.37 11.0 8.9 0.11 12.7 5.4 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding BST2 PF16716.5 EKX35867.1 - 0.71 10.5 8.9 0.55 10.8 5.9 2.2 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 HIF-1a_CTAD PF08778.10 EKX35869.1 - 0.095 12.3 0.1 3.4 7.4 0.1 2.5 2 0 0 2 2 2 0 HIF-1 alpha C terminal transactivation domain NTPase_I-T PF01931.18 EKX35870.1 - 4.1e-39 134.0 0.1 4.5e-39 133.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 YhfC PF10086.9 EKX35870.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 YhfC intramembrane metalloprotease ABC_membrane_2 PF06472.15 EKX35871.1 - 8e-53 179.6 2.2 1e-52 179.2 2.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 SbmA_BacA PF05992.12 EKX35871.1 - 3.2e-15 56.4 2.7 2.6e-14 53.4 2.7 2.1 1 1 0 1 1 1 1 SbmA/BacA-like family ABC_tran PF00005.27 EKX35871.1 - 1.2e-09 38.8 0.0 3.5e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EKX35871.1 - 2.6e-07 30.6 1.7 3.8e-07 30.0 1.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_29 PF13555.6 EKX35871.1 - 0.00014 21.6 0.1 0.00029 20.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EKX35871.1 - 0.00015 21.7 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 EKX35871.1 - 0.00016 22.2 0.2 0.0017 18.9 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 EKX35871.1 - 0.00065 20.0 0.1 0.0043 17.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EKX35871.1 - 0.0031 17.3 0.1 0.014 15.1 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EKX35871.1 - 0.0031 17.4 0.0 0.0069 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 EKX35871.1 - 0.0033 17.3 0.0 0.0078 16.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EKX35871.1 - 0.0036 17.7 0.0 0.0091 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 EKX35871.1 - 0.0053 16.8 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF815 PF05673.13 EKX35871.1 - 0.0098 15.1 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) SMC_N PF02463.19 EKX35871.1 - 0.014 14.9 0.6 0.4 10.1 0.1 2.4 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.18 EKX35871.1 - 0.016 14.6 0.6 0.038 13.4 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family OCD_Mu_crystall PF02423.15 EKX35871.1 - 0.046 12.7 0.0 0.07 12.1 0.0 1.1 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family AAA_7 PF12775.7 EKX35871.1 - 0.063 12.8 0.0 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region WD40 PF00400.32 EKX35873.1 - 4.1e-39 131.9 21.4 9.8e-08 32.6 0.0 11.7 12 0 0 12 12 12 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX35873.1 - 4.2e-23 81.5 0.0 0.014 15.7 0.0 8.8 4 2 4 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 EKX35873.1 - 4.9e-22 78.3 0.1 8.4e-22 77.5 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40_like PF17005.5 EKX35873.1 - 3.4e-09 36.4 0.0 7.1e-05 22.3 0.0 4.3 5 1 0 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 EKX35873.1 - 3.7e-06 26.1 0.1 7.1 5.5 0.0 5.3 4 2 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EKX35873.1 - 4.5e-06 26.7 2.6 0.02 14.8 0.1 5.6 5 2 2 7 7 7 1 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.6 EKX35873.1 - 0.0023 17.2 0.1 0.53 9.5 0.0 3.0 3 0 0 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus FLgD_tudor PF13861.6 EKX35873.1 - 0.15 12.3 0.9 22 5.4 0.1 3.2 3 0 0 3 3 3 0 FlgD Tudor-like domain ZinT PF09223.11 EKX35874.1 - 0.044 13.7 0.0 0.093 12.6 0.0 1.5 2 0 0 2 2 2 0 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment WD40 PF00400.32 EKX35877.1 - 9.8e-25 86.4 11.2 0.013 16.3 0.2 11.4 11 0 0 11 11 11 6 WD domain, G-beta repeat EF-hand_7 PF13499.6 EKX35877.1 - 2.6e-12 47.0 0.6 8.1e-12 45.4 0.6 1.9 1 0 0 1 1 1 1 EF-hand domain pair ANAPC4_WD40 PF12894.7 EKX35877.1 - 4.6e-09 36.5 0.2 0.24 11.7 0.0 5.7 4 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_8 PF13833.6 EKX35877.1 - 1.5e-08 34.3 0.5 3.9e-08 33.0 0.5 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX35877.1 - 6.5e-08 31.6 3.7 0.0024 17.3 0.1 3.7 2 1 1 3 3 3 2 EF hand EF-hand_6 PF13405.6 EKX35877.1 - 1.8e-07 30.5 2.7 0.0085 16.0 0.0 3.6 1 1 2 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 EKX35877.1 - 6.6e-07 28.5 5.9 0.00035 19.9 0.0 3.7 4 0 0 4 4 4 2 EF hand Nup160 PF11715.8 EKX35877.1 - 0.0013 17.5 2.4 0.16 10.6 0.0 4.0 4 0 0 4 4 4 1 Nucleoporin Nup120/160 EF-hand_4 PF12763.7 EKX35877.1 - 0.019 14.9 3.2 2 8.4 0.1 3.3 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand HTH_21 PF13276.6 EKX35878.1 - 6.5e-08 32.6 0.0 1.8e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 HTH-like domain M64_N PF16217.5 EKX35878.1 - 0.024 14.2 0.1 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 Peptidase M64 N-terminus Ephrin_rec_like PF07699.13 EKX35880.1 - 7.7e-08 32.0 20.5 2.6e-05 23.9 8.3 8.3 2 2 5 7 7 7 4 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX35880.1 - 0.067 13.6 55.7 0.082 13.3 0.1 7.4 5 2 2 7 7 7 0 TNFR/NGFR cysteine-rich region NHL PF01436.21 EKX35881.1 - 1.8e-11 43.5 4.4 0.042 13.9 0.1 5.6 5 0 0 5 5 5 4 NHL repeat Arylesterase PF01731.20 EKX35881.1 - 6e-08 32.8 0.7 0.13 12.5 0.0 4.7 5 0 0 5 5 5 3 Arylesterase Str_synth PF03088.16 EKX35881.1 - 1.6e-05 24.9 0.1 0.86 9.8 0.0 4.5 5 0 0 5 5 5 2 Strictosidine synthase SGL PF08450.12 EKX35881.1 - 0.0016 18.1 3.5 18 4.8 0.1 4.7 1 1 1 4 4 4 1 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 EKX35881.1 - 0.0024 17.2 0.2 2.4 7.3 0.0 2.7 2 1 0 2 2 2 2 Lactonase, 7-bladed beta-propeller LVIVD PF08309.11 EKX35881.1 - 0.014 14.7 4.4 5.9 6.3 0.0 4.2 4 0 0 4 4 4 0 LVIVD repeat Peptidase_C48 PF02902.19 EKX35882.1 - 6.2e-07 29.5 0.0 1.4e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Exo_endo_phos PF03372.23 EKX35882.1 - 0.0065 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EKX35882.1 - 0.02 14.7 0.0 0.06 13.2 0.0 1.8 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Glyco_hydro_36 PF17167.4 EKX35882.1 - 0.033 12.9 0.0 0.05 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain Pkinase_Tyr PF07714.17 EKX35884.1 - 9e-66 221.8 0.0 1e-65 221.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX35884.1 - 1.4e-32 113.1 0.0 1.6e-32 112.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Peptidase_C14 PF00656.22 EKX35885.1 - 7.3e-19 68.7 0.0 1.3e-18 67.9 0.0 1.4 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 EKX35885.1 - 0.033 14.1 0.0 2.3 8.2 0.0 2.9 2 1 0 2 2 2 0 Raptor N-terminal CASPase like domain PARP PF00644.20 EKX35886.1 - 5.6e-14 52.2 0.5 9e-13 48.2 0.5 2.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain WD40 PF00400.32 EKX35888.1 - 9.1e-31 105.4 34.3 1.2e-06 29.1 1.5 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX35888.1 - 1.2e-08 35.2 0.9 0.37 11.1 0.0 4.4 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EKX35888.1 - 0.00025 20.5 0.3 0.61 9.4 0.0 2.3 1 1 0 2 2 2 2 WD40-like domain PQQ_3 PF13570.6 EKX35888.1 - 0.00034 21.0 0.1 3 8.5 0.0 4.2 4 1 0 4 4 4 2 PQQ-like domain PQQ PF01011.21 EKX35888.1 - 0.00049 19.9 0.0 0.14 12.1 0.0 3.0 3 0 0 3 3 3 1 PQQ enzyme repeat Nup160 PF11715.8 EKX35888.1 - 0.0023 16.6 2.1 1.3 7.6 0.0 3.8 1 1 2 4 4 4 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 EKX35888.1 - 0.0064 16.1 0.1 0.03 13.9 0.0 2.1 2 1 1 3 3 3 1 PQQ-like domain BBS2_Mid PF14783.6 EKX35888.1 - 0.025 14.6 0.0 6.4 6.9 0.0 3.5 2 1 2 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.11 EKX35888.1 - 0.037 12.8 0.1 1.2 7.8 0.0 2.7 1 1 2 3 3 3 0 Nup133 N terminal like RCC1 PF00415.18 EKX35889.1 - 1.1e-66 221.2 37.1 4.9e-16 59.1 1.2 6.1 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX35889.1 - 4.8e-32 109.1 44.2 2.2e-07 30.5 4.4 6.7 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 EKX35889.1 - 0.35 10.6 1.8 36 4.0 0.1 3.2 4 0 0 4 4 4 0 TUP1-like enhancer of split PapC_C PF13953.6 EKX35889.1 - 0.92 9.4 4.6 3.7 7.4 0.2 3.4 4 0 0 4 4 4 0 PapC C-terminal domain PDEase_I PF00233.19 EKX35891.1 - 2.2e-75 253.4 0.2 2.7e-75 253.2 0.2 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase zf-C2H2_6 PF13912.6 EKX35891.1 - 0.038 14.0 0.1 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger HD PF01966.22 EKX35891.1 - 0.073 13.3 0.5 0.17 12.1 0.3 1.5 1 1 0 1 1 1 0 HD domain DUF3446 PF11928.8 EKX35892.1 - 0.093 13.0 9.2 0.12 12.6 8.0 1.7 2 0 0 2 2 2 0 Early growth response N-terminal domain Nic96 PF04097.14 EKX35893.1 - 0.019 13.4 0.0 0.026 13.0 0.0 1.1 1 0 0 1 1 1 0 Nup93/Nic96 Spt5_N PF11942.8 EKX35894.1 - 0.0047 17.9 0.9 0.0047 17.9 0.9 5.9 6 0 0 6 6 6 2 Spt5 transcription elongation factor, acidic N-terminal Pkinase_fungal PF17667.1 EKX35894.1 - 5 5.8 6.8 22 3.7 6.8 2.0 1 1 0 1 1 1 0 Fungal protein kinase GRP PF07172.11 EKX35894.1 - 8.8 7.1 53.8 0.34 11.6 5.6 4.9 5 0 0 5 5 5 0 Glycine rich protein family EspB_PE PF18625.1 EKX35895.1 - 0.0062 17.0 0.1 0.046 14.2 0.1 2.6 1 0 0 1 1 1 1 ESX-1 secreted protein B PE domain DUF2188 PF09954.9 EKX35897.1 - 0.0011 19.1 10.9 30 4.8 0.1 8.4 2 2 10 12 12 12 3 Uncharacterized protein conserved in bacteria (DUF2188) CRIC_ras_sig PF10534.9 EKX35898.1 - 0.00067 19.8 0.0 14 6.0 0.0 3.8 1 1 3 4 4 4 3 Connector enhancer of kinase suppressor of ras SH3_16 PF18348.1 EKX35898.1 - 0.035 13.9 2.5 16 5.4 0.0 3.6 4 0 0 4 4 4 0 Bacterial dipeptidyl-peptidase Sh3 domain DUF5546 PF17700.1 EKX35898.1 - 4.9 7.5 13.6 11 6.4 0.8 3.3 1 1 2 3 3 3 0 Family of unknown function (DUF5546) DUF2188 PF09954.9 EKX35899.1 - 0.00035 20.6 5.0 5 7.3 0.1 6.1 1 1 6 8 8 8 4 Uncharacterized protein conserved in bacteria (DUF2188) DUF2188 PF09954.9 EKX35901.1 - 9.4e-06 25.7 2.8 23 5.2 0.0 6.2 1 1 7 8 8 8 4 Uncharacterized protein conserved in bacteria (DUF2188) DUF3377 PF11857.8 EKX35902.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) SelR PF01641.18 EKX35903.1 - 0.011 15.7 0.2 0.02 15.0 0.2 1.4 1 0 0 1 1 1 0 SelR domain DUF5635 PF18685.1 EKX35903.1 - 0.13 12.2 0.0 0.43 10.5 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5635) Nucleos_tra2_C PF07662.13 EKX35904.1 - 1.1e-24 87.5 0.0 1.1e-24 87.5 0.0 2.2 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 EKX35904.1 - 2.3e-19 69.8 8.7 2.9e-19 69.4 1.6 2.8 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 EKX35904.1 - 4.5e-05 23.7 3.5 4.5e-05 23.7 3.5 2.6 2 1 1 3 3 3 1 Nucleoside recognition Asp_protease PF09668.10 EKX35904.1 - 0.079 12.8 0.0 3.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease PMP1_2 PF08114.11 EKX35904.1 - 2.6 7.9 5.0 1.5 8.6 0.3 2.6 2 0 0 2 2 2 0 ATPase proteolipid family EF-hand_1 PF00036.32 EKX35905.1 - 0.0005 19.4 0.2 0.9 9.2 0.0 2.5 2 0 0 2 2 2 2 EF hand PEGA PF08308.11 EKX35905.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 PEGA domain DUF2012 PF09430.10 EKX35905.1 - 0.062 13.4 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) EF-hand_6 PF13405.6 EKX35905.1 - 0.099 12.6 0.1 8.5 6.6 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 EKX35905.1 - 0.13 12.7 0.4 0.47 10.9 0.4 1.9 1 1 0 1 1 1 0 EF-hand domain pair CarboxypepD_reg PF13620.6 EKX35905.1 - 0.2 11.9 0.6 1.1 9.5 0.3 2.3 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain Arm PF00514.23 EKX35906.1 - 2.9e-08 33.5 2.7 0.0031 17.5 0.1 3.2 3 0 0 3 3 3 3 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EKX35906.1 - 0.00024 21.1 0.1 0.3 11.2 0.0 2.2 1 1 1 2 2 2 2 Spinocerebellar ataxia type 10 protein domain DHO_dh PF01180.21 EKX35906.1 - 0.03 13.5 0.2 1 8.5 0.0 2.1 1 1 0 2 2 2 0 Dihydroorotate dehydrogenase HEAT_EZ PF13513.6 EKX35906.1 - 0.059 13.9 0.5 3.6 8.2 0.5 3.0 1 1 0 1 1 1 0 HEAT-like repeat DUF4630 PF15443.6 EKX35906.1 - 1.1 9.4 6.1 1.3 9.2 1.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4630) DUF745 PF05335.13 EKX35907.1 - 0.01 15.6 13.2 0.01 15.6 13.2 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF745) GIT_CC PF16559.5 EKX35907.1 - 0.51 10.2 11.8 2.7 7.9 0.3 3.6 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Spc7 PF08317.11 EKX35907.1 - 2.7 6.8 47.4 0.28 10.0 16.7 2.8 3 1 0 3 3 3 0 Spc7 kinetochore protein ANAPC4_WD40 PF12894.7 EKX35908.1 - 2.6e-12 46.9 0.1 2.8e-07 30.7 0.1 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EKX35908.1 - 3.2e-07 30.9 0.4 0.011 16.5 0.4 2.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.8 EKX35908.1 - 2e-05 23.4 0.1 0.058 12.0 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Hira PF07569.11 EKX35908.1 - 0.0016 18.2 0.0 0.088 12.5 0.0 2.0 1 1 1 2 2 2 1 TUP1-like enhancer of split Nucleoporin_N PF08801.11 EKX35908.1 - 0.0087 14.8 0.1 0.37 9.5 0.0 2.0 1 1 1 2 2 2 2 Nup133 N terminal like PQQ_2 PF13360.6 EKX35908.1 - 0.021 14.4 0.0 0.032 13.8 0.0 1.3 1 1 0 1 1 1 0 PQQ-like domain PD40 PF07676.12 EKX35908.1 - 0.026 14.5 0.7 39 4.3 0.0 3.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PQQ PF01011.21 EKX35908.1 - 0.054 13.4 0.0 8 6.6 0.0 2.4 2 0 0 2 2 2 0 PQQ enzyme repeat DUF4597 PF15366.6 EKX35908.1 - 0.1 12.3 0.1 3.2 7.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) DUF908 PF06012.12 EKX35909.1 - 0.013 15.0 20.1 0.023 14.1 20.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF913 PF06025.12 EKX35909.1 - 3.4 6.6 20.6 0.11 11.5 12.9 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Pex14_N PF04695.13 EKX35909.1 - 6 7.5 46.4 0.28 11.8 38.6 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SID-1_RNA_chan PF13965.6 EKX35909.1 - 6.4 5.1 18.8 0.59 8.5 9.9 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 PPL5 PF18168.1 EKX35909.1 - 7.6 5.7 27.0 0.93 8.7 18.3 2.5 2 0 0 2 2 2 0 Prim-pol family 5 Arm PF00514.23 EKX35910.1 - 2e-24 84.8 44.7 0.00026 20.9 0.2 9.5 9 1 1 10 10 10 8 Armadillo/beta-catenin-like repeat DHO_dh PF01180.21 EKX35910.1 - 2.5e-17 63.0 5.0 0.24 10.6 0.0 7.9 3 2 5 8 8 8 6 Dihydroorotate dehydrogenase Atx10homo_assoc PF09759.9 EKX35910.1 - 3.4e-16 59.1 1.6 0.018 15.0 0.0 6.8 1 1 8 9 9 9 7 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 EKX35910.1 - 9.8e-07 28.5 0.2 0.3 10.5 0.0 3.4 2 2 0 3 3 3 2 Armadillo-like Reprolysin_5 PF13688.6 EKX35910.1 - 1e-05 25.8 4.9 0.1 12.7 0.1 4.3 1 1 1 3 3 3 2 Metallo-peptidase family M12 CDC37_C PF08564.10 EKX35910.1 - 0.00018 21.5 0.5 12 6.0 0.0 5.1 3 1 3 6 6 6 1 Cdc37 C terminal domain MLVIN_C PF18697.1 EKX35910.1 - 0.0052 16.9 0.9 83 3.4 0.0 4.3 3 1 2 5 5 5 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain DXP_synthase_N PF13292.6 EKX35910.1 - 0.15 11.2 0.2 17 4.5 0.0 3.6 1 1 3 5 5 5 0 1-deoxy-D-xylulose-5-phosphate synthase Glyco_hydro_98C PF08307.11 EKX35910.1 - 0.15 11.5 0.0 13 5.2 0.0 2.8 2 1 1 3 3 3 0 Glycosyl hydrolase family 98 C-terminal domain TerB PF05099.13 EKX35910.1 - 0.16 11.9 18.9 0.36 10.8 0.1 5.3 3 1 2 5 5 5 0 Tellurite resistance protein TerB Alkyl_sulf_dimr PF14863.6 EKX35910.1 - 1.6 9.1 16.3 2 8.9 0.1 5.6 2 1 3 6 6 6 0 Alkyl sulfatase dimerisation Spt20 PF12090.8 EKX35911.1 - 0.003 17.2 35.1 0.003 17.2 35.1 2.6 2 1 0 2 2 2 1 Spt20 family PepSY_TM PF03929.16 EKX35911.1 - 0.2 11.3 3.2 0.41 10.3 3.2 1.6 1 0 0 1 1 1 0 PepSY-associated TM region Velvet PF11754.8 EKX35911.1 - 0.67 9.8 16.2 0.021 14.8 7.3 2.4 2 0 0 2 2 2 0 Velvet factor CinA_KH PF18146.1 EKX35911.1 - 6.8 6.9 7.4 1.5 9.1 0.2 3.5 3 0 0 3 3 3 0 Damage-inducible protein CinA KH domain Arm PF00514.23 EKX35912.1 - 2e-16 59.4 22.0 0.078 13.0 0.1 7.9 7 1 1 8 8 8 6 Armadillo/beta-catenin-like repeat CRS1_YhbY PF01985.21 EKX35912.1 - 5.6e-06 26.4 1.0 10 6.4 0.0 6.0 3 1 3 6 6 6 1 CRS1 / YhbY (CRM) domain HEAT_EZ PF13513.6 EKX35912.1 - 8.4e-06 26.2 14.8 9.5 6.8 0.0 6.5 5 1 1 6 6 6 3 HEAT-like repeat DHO_dh PF01180.21 EKX35912.1 - 1.8e-05 24.1 11.5 2.9 7.0 0.0 6.2 2 1 5 7 7 7 4 Dihydroorotate dehydrogenase Atx10homo_assoc PF09759.9 EKX35912.1 - 2.5e-05 24.2 0.0 4.8 7.3 0.0 5.1 1 1 6 7 7 7 2 Spinocerebellar ataxia type 10 protein domain Rhabdo_matrix PF03397.14 EKX35912.1 - 0.02 14.6 0.1 54 3.5 0.0 4.4 5 0 0 5 5 5 0 Rhabdovirus matrix protein SLATT_fungal PF18142.1 EKX35912.1 - 0.64 10.0 26.9 16 5.5 0.2 6.6 1 1 6 7 7 7 0 SMODS and SLOG-associating 2TM effector domain RCC1 PF00415.18 EKX35912.1 - 1.3 9.7 5.9 75 4.1 0.0 4.7 5 0 0 5 5 5 0 Regulator of chromosome condensation (RCC1) repeat Atx10homo_assoc PF09759.9 EKX35913.1 - 0.0066 16.5 0.2 1.8 8.7 0.0 3.3 3 1 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 EKX35913.1 - 0.053 13.6 0.9 0.4 10.8 0.0 2.9 3 1 1 4 4 4 0 Armadillo/beta-catenin-like repeat CCDC53 PF10152.9 EKX35914.1 - 4.6 7.7 22.6 5.3 7.4 11.1 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Arm PF00514.23 EKX35915.1 - 7.4e-22 76.6 31.6 7.6e-06 25.8 0.3 8.7 9 0 0 9 9 9 6 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EKX35915.1 - 3.9e-11 42.9 0.1 1.4 9.0 0.0 6.7 1 1 7 8 8 8 3 Spinocerebellar ataxia type 10 protein domain DHO_dh PF01180.21 EKX35915.1 - 3.1e-05 23.3 17.7 1.2 8.3 0.0 7.5 2 2 6 8 8 8 2 Dihydroorotate dehydrogenase AurF PF11583.8 EKX35915.1 - 0.00061 19.2 2.2 19 4.4 0.1 5.5 2 1 5 7 7 7 0 P-aminobenzoate N-oxygenase AurF CRS1_YhbY PF01985.21 EKX35915.1 - 0.0062 16.7 0.7 14 5.9 0.0 4.9 4 2 2 6 6 6 1 CRS1 / YhbY (CRM) domain DXP_synthase_N PF13292.6 EKX35915.1 - 0.01 15.1 3.0 6.2 5.9 0.0 3.9 1 1 1 4 4 4 0 1-deoxy-D-xylulose-5-phosphate synthase Flt3_lig PF02947.14 EKX35915.1 - 0.052 13.7 0.1 6.9 6.9 0.0 3.2 3 1 0 3 3 3 0 flt3 ligand DUF3302 PF11742.8 EKX35915.1 - 0.15 12.2 10.0 15 5.8 0.2 6.1 4 2 3 7 7 7 0 Protein of unknown function (DUF3302) Ribo_biogen_C PF04034.13 EKX35915.1 - 0.29 10.8 11.4 14 5.5 0.0 5.0 1 1 5 6 6 6 0 Ribosome biogenesis protein, C-terminal zf_C2HC_14 PF18574.1 EKX35915.1 - 0.4 10.5 12.5 1.3e+02 2.5 0.0 7.2 9 0 0 9 9 9 0 C2HC Zing finger domain PHY PF00360.20 EKX35915.1 - 2.6 7.3 16.4 26 4.0 0.1 6.2 8 0 0 8 8 8 0 Phytochrome region Alkyl_sulf_dimr PF14863.6 EKX35915.1 - 5.5 7.5 14.7 18 5.8 0.2 5.5 1 1 5 6 6 6 0 Alkyl sulfatase dimerisation TMEM223 PF14640.6 EKX35916.1 - 0.095 12.9 0.0 0.18 12.0 0.0 1.6 1 1 0 1 1 1 0 Transmembrane protein 223 Fer2 PF00111.27 EKX35918.1 - 1.3e-07 31.5 3.5 3.9e-07 29.9 3.5 1.8 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF3160 PF11369.8 EKX35919.1 - 0.12 10.9 0.1 0.96 7.8 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3160) LRR_8 PF13855.6 EKX35921.1 - 9.1e-79 259.2 50.4 4.9e-15 55.0 0.4 6.5 1 1 6 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 EKX35921.1 - 5.6e-33 112.4 22.7 6e-06 26.5 0.9 7.7 4 1 4 9 9 9 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX35921.1 - 6e-24 84.4 0.0 1e-09 38.5 0.0 3.1 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EKX35921.1 - 1.3e-13 49.4 22.4 1.5 9.7 0.1 10.6 11 0 0 11 11 11 4 Leucine Rich Repeat LRR_9 PF14580.6 EKX35921.1 - 8.6e-09 35.1 0.0 0.069 12.7 0.0 4.3 1 1 4 5 5 5 4 Leucine-rich repeat Ribosomal_S5_C PF03719.15 EKX35921.1 - 0.037 13.5 0.0 8.4 5.9 0.0 3.1 3 0 0 3 3 3 0 Ribosomal protein S5, C-terminal domain LRR_6 PF13516.6 EKX35921.1 - 4.9 7.5 30.6 6.2 7.1 0.3 8.9 9 0 0 9 9 9 0 Leucine Rich repeat DUF2675 PF11247.8 EKX35925.1 - 0.92 9.7 10.8 21 5.3 0.1 4.5 1 1 4 5 5 5 0 Protein of unknown function (DUF2675) Atrophin-1 PF03154.15 EKX35930.1 - 0.054 11.8 0.5 0.063 11.6 0.5 1.1 1 0 0 1 1 1 0 Atrophin-1 family HECT PF00632.25 EKX35931.1 - 4e-22 79.1 0.0 4.3e-22 79.0 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBA PF00627.31 EKX35932.1 - 0.00053 19.8 0.1 0.0012 18.7 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Methyltransf_21 PF05050.12 EKX35933.1 - 0.006 16.6 0.0 0.0067 16.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase FkbM domain VQ PF05678.14 EKX35933.1 - 0.062 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 VQ motif DIM1 PF02966.16 EKX35934.1 - 4e-67 224.0 0.2 4.5e-67 223.9 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 EKX35934.1 - 3.7e-05 23.6 0.0 4.8e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EKX35934.1 - 0.016 15.5 0.2 0.035 14.4 0.1 1.6 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_7 PF13899.6 EKX35934.1 - 0.043 14.0 0.0 0.074 13.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like GidB PF02527.15 EKX35934.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G RWP-RK PF02042.15 EKX35935.1 - 1.4e-22 79.4 0.2 1.6e-22 79.2 0.2 1.1 1 0 0 1 1 1 1 RWP-RK domain HTH_17 PF12728.7 EKX35935.1 - 0.018 15.2 0.3 0.24 11.6 0.2 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain DUF3338 PF11819.8 EKX35935.1 - 0.17 11.8 0.1 0.19 11.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3338) SDA1 PF05285.12 EKX35936.1 - 6.4e-05 22.5 30.6 7.5e-05 22.3 30.6 1.0 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 EKX35936.1 - 0.0017 16.7 30.6 0.0018 16.6 30.6 1.0 1 0 0 1 1 1 1 Nop14-like family PNISR PF15996.5 EKX35936.1 - 0.51 10.6 9.2 0.63 10.3 9.2 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Drc1-Sld2 PF11719.8 EKX35936.1 - 7 6.1 13.6 8.8 5.8 13.6 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein BUD22 PF09073.10 EKX35936.1 - 9.4 5.4 32.8 12 5.2 32.8 1.1 1 0 0 1 1 1 0 BUD22 WAP PF00095.21 EKX35938.1 - 0.7 10.3 13.9 0.11 12.9 3.8 3.3 2 1 1 3 3 3 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' PDZ_6 PF17820.1 EKX35941.1 - 3.6e-21 74.8 0.0 5e-13 48.7 0.0 2.7 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 EKX35941.1 - 1.7e-18 66.7 3.4 5e-11 42.8 0.1 3.3 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 EKX35941.1 - 3.3e-15 56.2 0.1 2.2e-08 34.3 0.1 2.6 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 EKX35941.1 - 1.1e-05 25.3 0.1 0.042 13.8 0.0 3.4 2 2 0 2 2 2 2 Tricorn protease PDZ domain Remorin_C PF03763.13 EKX35942.1 - 7.4 6.5 23.5 0.091 12.6 14.7 2.0 2 0 0 2 2 2 0 Remorin, C-terminal region 2OG-FeII_Oxy_2 PF13532.6 EKX35943.1 - 2.1e-13 50.9 0.0 9e-12 45.6 0.0 2.1 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily CLP_protease PF00574.23 EKX35944.1 - 2.1e-54 184.2 0.2 2.3e-54 184.0 0.2 1.0 1 0 0 1 1 1 1 Clp protease SDH_sah PF01972.16 EKX35944.1 - 0.0049 15.9 0.1 0.0055 15.7 0.1 1.1 1 0 0 1 1 1 1 Serine dehydrogenase proteinase RnfC_N PF13375.6 EKX35944.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain HHH_3 PF12836.7 EKX35945.1 - 0.06 13.6 0.0 0.094 13.0 0.0 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix motif EF_TS PF00889.19 EKX35946.1 - 0.057 13.0 0.3 0.1 12.2 0.3 1.4 1 0 0 1 1 1 0 Elongation factor TS Glyco_hydro_99 PF16317.5 EKX35948.1 - 3.2e-48 164.6 0.2 4.7e-48 164.1 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 99 IF4E PF01652.18 EKX35949.1 - 1.8e-40 138.3 0.9 2.3e-40 138.0 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E IBR PF01485.21 EKX35950.1 - 1.7e-12 47.4 24.0 1.8e-08 34.5 7.1 2.1 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain IBR PF01485.21 EKX35951.1 - 9.5e-15 54.6 47.2 1.2e-08 35.1 3.0 4.3 1 1 3 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EKX35951.1 - 2.2e-07 31.1 5.2 2.2e-07 31.1 5.2 4.2 1 1 4 5 5 5 1 Ring finger domain zf-RING_UBOX PF13445.6 EKX35951.1 - 5.3e-05 23.2 5.8 5.3e-05 23.2 5.8 3.9 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EKX35951.1 - 8.5e-05 22.3 4.6 8.5e-05 22.3 4.6 4.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX35951.1 - 0.00013 21.8 4.2 0.00013 21.8 4.2 4.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EKX35951.1 - 0.00058 19.6 5.9 0.00058 19.6 5.9 3.0 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_5 PF14634.6 EKX35951.1 - 0.00099 19.0 7.1 0.00099 19.0 7.1 4.3 3 1 0 3 3 3 2 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EKX35951.1 - 0.03 14.5 6.3 0.03 14.5 6.3 5.2 2 2 2 4 4 4 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EKX35951.1 - 3.5 7.5 43.1 1.1 9.2 7.9 4.4 2 1 2 4 4 4 0 RING/Ubox like zinc-binding domain NSP2_assoc PF14758.6 EKX35952.1 - 0.0014 19.0 1.0 0.45 10.8 0.1 2.1 1 1 1 2 2 2 2 Non-essential region of nsp2 of arterivirus polyprotein TagF_N PF09867.9 EKX35952.1 - 0.0064 16.5 0.2 4.2 7.4 0.0 2.2 2 0 0 2 2 2 2 TagF N-terminal domain, Type VI secretion system-associated DUF1492 PF07374.11 EKX35952.1 - 0.026 14.7 0.2 9.2 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) PPR PF01535.20 EKX35953.1 - 4.7e-05 23.3 0.0 0.74 10.2 0.0 3.5 3 1 0 3 3 3 2 PPR repeat PPR_2 PF13041.6 EKX35953.1 - 0.00056 20.0 0.1 2.7 8.3 0.0 2.9 2 1 1 3 3 3 2 PPR repeat family PPR_1 PF12854.7 EKX35953.1 - 0.00062 19.4 0.8 0.075 12.7 0.2 3.0 2 1 0 2 2 2 1 PPR repeat Kringle PF00051.18 EKX35953.1 - 0.057 13.7 0.1 0.12 12.7 0.0 1.6 2 0 0 2 2 2 0 Kringle domain Paramyx_P_V_C PF03210.13 EKX35953.1 - 0.068 13.0 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal Cas_Csa4 PF09703.10 EKX35953.1 - 0.077 12.3 0.0 0.079 12.3 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa4) BRICHOS PF04089.14 EKX35953.1 - 0.077 13.2 0.4 1.3 9.3 0.2 2.1 1 1 1 2 2 2 0 BRICHOS domain Erf4 PF10256.9 EKX35954.1 - 0.0016 18.5 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Peptidase_A24 PF01478.18 EKX35954.1 - 0.0071 16.7 2.0 0.012 16.0 2.0 1.2 1 0 0 1 1 1 1 Type IV leader peptidase family DUF4203 PF13886.6 EKX35954.1 - 0.022 14.4 1.3 0.037 13.7 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) SP_C-Propep PF08999.10 EKX35955.1 - 0.019 14.7 1.9 0.042 13.6 1.9 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide NS3_envE PF02723.14 EKX35955.1 - 0.033 14.3 0.2 0.066 13.3 0.2 1.5 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E Lsr2 PF11774.8 EKX35955.1 - 0.26 11.4 3.8 0.23 11.6 0.1 2.7 3 0 0 3 3 3 0 Lsr2 CENP-B_dimeris PF09026.10 EKX35955.1 - 5.9 7.3 9.9 3.3 8.2 5.0 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Fer4_8 PF13183.6 EKX35955.1 - 7.4 7.1 9.0 0.45 11.0 0.2 3.1 2 1 1 3 3 3 0 4Fe-4S dicluster domain HIG_1_N PF04588.13 EKX35956.1 - 1.1e-16 60.7 0.2 1.5e-16 60.3 0.2 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region PAD_porph PF04371.15 EKX35957.1 - 0.14 11.4 0.1 0.17 11.1 0.1 1.1 1 0 0 1 1 1 0 Porphyromonas-type peptidyl-arginine deiminase EF-1_beta_acid PF10587.9 EKX35957.1 - 0.38 11.2 3.9 0.7 10.4 3.9 1.4 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region PKD_channel PF08016.12 EKX35958.1 - 6.1e-36 124.0 18.9 6.1e-36 124.0 18.9 2.4 2 1 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 EKX35958.1 - 4.4e-12 45.7 23.6 4.6e-12 45.7 19.8 2.1 2 0 0 2 2 2 1 Ion transport protein Hum_adeno_E3A PF05393.11 EKX35958.1 - 0.027 14.5 0.2 0.077 13.0 0.2 1.7 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein DivIC PF04977.15 EKX35958.1 - 0.53 10.1 0.0 0.53 10.1 0.0 2.9 3 0 0 3 3 3 0 Septum formation initiator SAP PF02037.27 EKX35959.1 - 2.9e-12 46.0 4.4 3.3e-12 45.8 2.7 2.0 2 0 0 2 2 2 1 SAP domain zf-C2H2_10 PF16588.5 EKX35959.1 - 1.8e-05 24.3 2.5 3e-05 23.7 2.5 1.3 1 0 0 1 1 1 1 C2H2 zinc-finger zf-CCHC PF00098.23 EKX35959.1 - 0.22 11.7 0.7 0.4 10.9 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle Kelch_1 PF01344.25 EKX35960.1 - 8e-09 34.9 0.0 2e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 Kelch motif Kelch_6 PF13964.6 EKX35960.1 - 0.00031 20.9 0.4 0.0012 19.1 0.3 2.1 1 1 0 1 1 1 1 Kelch motif Kelch_4 PF13418.6 EKX35960.1 - 0.085 12.9 0.1 0.14 12.2 0.1 1.6 1 1 0 1 1 1 0 Galactose oxidase, central domain Plasmodium_HRP PF05403.11 EKX35961.1 - 0.011 15.5 0.2 0.013 15.3 0.2 1.0 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) TLD PF07534.16 EKX35962.1 - 3.2e-26 92.2 1.5 1.5e-13 51.2 0.8 2.3 2 0 0 2 2 2 2 TLD BTB_2 PF02214.22 EKX35962.1 - 8.3e-15 54.9 0.0 1.1e-06 28.9 0.0 3.4 2 1 0 2 2 2 2 BTB/POZ domain HeLo PF14479.6 EKX35962.1 - 0.39 10.5 3.2 3 7.6 0.6 2.3 2 0 0 2 2 2 0 Prion-inhibition and propagation Cluap1 PF10234.9 EKX35962.1 - 8.8 5.6 7.1 1.5 8.2 1.3 2.1 2 0 0 2 2 2 0 Clusterin-associated protein-1 PseudoU_synth_2 PF00849.22 EKX35966.1 - 2.8e-08 34.0 0.1 8.8e-08 32.4 0.1 1.9 1 1 0 1 1 1 1 RNA pseudouridylate synthase Drc1-Sld2 PF11719.8 EKX35966.1 - 0.0011 18.6 4.8 0.0018 17.9 0.9 2.1 2 0 0 2 2 2 1 DNA replication and checkpoint protein RWP-RK PF02042.15 EKX35967.1 - 6.7e-22 77.2 0.0 8.5e-22 76.9 0.0 1.1 1 0 0 1 1 1 1 RWP-RK domain DUF501 PF04417.12 EKX35968.1 - 1e-15 57.8 0.0 2.2e-15 56.7 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF501) Zip PF02535.22 EKX35972.1 - 1.1 8.5 4.7 1.7 7.8 4.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DnaJ PF00226.31 EKX35974.1 - 1.8e-21 76.0 0.3 4.5e-21 74.7 0.3 1.7 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 EKX35974.1 - 4.4e-06 26.6 0.0 1.1e-05 25.3 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin SpoVR PF04293.13 EKX35974.1 - 0.089 11.5 1.4 0.14 10.8 1.4 1.2 1 0 0 1 1 1 0 SpoVR like protein COX8 PF02285.15 EKX35975.1 - 0.21 11.5 1.5 0.74 9.7 0.0 2.4 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII Ank_4 PF13637.6 EKX35976.1 - 5e-14 52.5 0.0 5.9e-13 49.0 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX35976.1 - 2.6e-10 40.7 0.0 9.2e-10 39.0 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX35976.1 - 4.9e-10 39.5 0.3 3.7e-08 33.5 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX35976.1 - 1.2e-08 35.0 0.1 2.4e-05 24.6 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EKX35976.1 - 1.7e-07 31.0 0.0 0.017 15.6 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat PTSIIB_sorb PF03830.15 EKX35976.1 - 0.02 15.1 0.0 2.4 8.4 0.0 2.3 2 0 0 2 2 2 0 PTS system sorbose subfamily IIB component Arg_decarb_HB PF17810.1 EKX35976.1 - 0.17 12.2 0.7 2.5 8.4 0.0 2.9 3 0 0 3 3 3 0 Arginine decarboxylase helical bundle domain Pkinase PF00069.25 EKX35977.1 - 6e-27 94.7 0.0 1e-26 93.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX35977.1 - 2.2e-13 50.1 0.0 4.5e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PA PF02225.22 EKX35977.1 - 2.7e-09 36.9 1.3 6.1e-09 35.8 1.3 1.6 1 0 0 1 1 1 1 PA domain LRR_6 PF13516.6 EKX35977.1 - 0.00014 21.6 4.6 1.1 9.5 1.3 3.8 2 1 1 3 3 3 2 Leucine Rich repeat DSPc PF00782.20 EKX35977.1 - 0.0004 20.2 0.0 0.0017 18.2 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.6 EKX35977.1 - 0.00091 18.9 3.1 0.02 14.6 3.1 2.9 1 1 1 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 EKX35977.1 - 0.028 14.8 3.3 0.68 10.4 3.3 2.7 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX35977.1 - 1.8 9.4 7.5 2.6e+02 2.8 0.0 4.9 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 EKX35978.1 - 9e-11 40.9 0.3 0.00036 20.3 0.0 4.5 4 0 0 4 4 4 2 Leucine Rich repeat UBA PF00627.31 EKX35978.1 - 0.00031 20.6 0.1 0.00059 19.7 0.1 1.4 1 0 0 1 1 1 1 UBA/TS-N domain LRR_4 PF12799.7 EKX35978.1 - 0.046 14.2 0.4 61 4.2 0.0 3.5 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) RecX PF02631.16 EKX35978.1 - 0.067 13.7 0.1 0.12 12.9 0.1 1.4 1 0 0 1 1 1 0 RecX family OAM_alpha PF16552.5 EKX35978.1 - 0.11 12.4 0.0 0.41 10.5 0.0 1.9 2 0 0 2 2 2 0 D-ornithine 4,5-aminomutase alpha-subunit Phycoerythr_ab PF02972.14 EKX35979.1 - 2.4e-26 91.3 0.1 3.2e-26 90.9 0.1 1.2 1 0 0 1 1 1 1 Phycoerythrin, alpha/beta chain Pkinase PF00069.25 EKX35980.1 - 5.3e-52 176.8 0.0 1.4e-51 175.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX35980.1 - 2.5e-27 95.8 0.2 4.3e-24 85.2 0.3 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 EKX35980.1 - 2.5e-05 23.8 0.0 4.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EKX35980.1 - 0.039 13.9 0.1 0.075 12.9 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 EKX35980.1 - 0.042 13.5 0.3 0.064 12.8 0.3 1.4 1 1 0 1 1 1 0 RIO1 family ABC1 PF03109.16 EKX35980.1 - 0.065 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Kdo PF06293.14 EKX35980.1 - 0.074 12.4 0.9 0.12 11.8 0.9 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Metallophos PF00149.28 EKX35981.1 - 5e-21 76.1 0.8 5.3e-20 72.8 0.1 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 EKX35981.1 - 4e-14 53.2 0.1 1.4e-13 51.5 0.1 2.0 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 EKX35981.1 - 6.3e-09 36.3 3.0 1.3e-08 35.3 0.2 2.7 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain DSBA PF01323.20 EKX35982.1 - 7.4e-31 107.4 0.2 8.7e-31 107.2 0.2 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EKX35982.1 - 0.004 17.3 0.0 0.0052 17.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin BCDHK_Adom3 PF10436.9 EKX35983.1 - 3.3e-36 124.6 1.4 4.6e-36 124.1 1.4 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EKX35983.1 - 1.9e-11 44.4 0.0 2.2e-10 41.0 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EKX35983.1 - 0.0039 17.0 0.0 0.0067 16.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3313 PF11769.8 EKX35983.1 - 0.2 11.5 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) MFS_5 PF05631.14 EKX35984.1 - 4.7e-75 252.7 5.7 5.9e-75 252.4 5.7 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 EKX35984.1 - 4.5e-18 65.3 16.4 5.6e-18 65.0 16.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EKX35984.1 - 5.1e-06 25.6 7.2 5.1e-06 25.6 7.2 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter DUF21 PF01595.20 EKX35984.1 - 0.00099 18.9 1.1 0.0031 17.2 0.0 2.4 3 0 0 3 3 3 1 Cyclin M transmembrane N-terminal domain GRIM-19 PF06212.12 EKX35985.1 - 5.4e-34 117.0 0.1 6.7e-34 116.7 0.1 1.1 1 0 0 1 1 1 1 GRIM-19 protein HAT_KAT11 PF08214.11 EKX35986.1 - 0.034 13.4 0.2 0.13 11.5 0.0 1.6 1 1 1 2 2 2 0 Histone acetylation protein XG_FTase PF03254.13 EKX35989.1 - 2e-06 26.7 0.0 0.1 11.2 0.0 3.1 2 1 1 3 3 3 3 Xyloglucan fucosyltransferase NodZ PF05830.11 EKX35989.1 - 0.0062 15.4 0.0 0.37 9.6 0.0 2.7 2 1 0 2 2 2 2 Nodulation protein Z (NodZ) Viral_helicase1 PF01443.18 EKX35990.1 - 0.084 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Calici_MSP PF05752.11 EKX35990.1 - 0.11 12.4 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Calicivirus minor structural protein Baculo_PEP_C PF04513.12 EKX35992.1 - 1.1 9.3 5.7 0.61 10.1 0.6 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Hydrolase_4 PF12146.8 EKX35993.1 - 4.1e-15 55.7 0.1 5.9e-13 48.6 0.1 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EKX35993.1 - 2.5e-14 53.6 0.1 1e-13 51.5 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EKX35993.1 - 2.2e-07 31.7 0.3 3e-07 31.3 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 EKX35993.1 - 1.9e-06 27.7 0.0 3.6e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF1749 PF08538.10 EKX35993.1 - 0.0012 18.0 0.0 0.0019 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) FSH1 PF03959.13 EKX35993.1 - 0.0016 18.1 0.0 0.0037 16.9 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) PAF-AH_p_II PF03403.13 EKX35993.1 - 0.013 14.0 0.0 3.1 6.2 0.0 2.1 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Peptidase_S9 PF00326.21 EKX35993.1 - 0.019 14.5 0.1 0.17 11.3 0.1 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase PF00756.20 EKX35993.1 - 0.046 13.4 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative esterase BAAT_C PF08840.11 EKX35993.1 - 0.094 12.6 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF915 PF06028.11 EKX35993.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) NMT1 PF09084.11 EKX35994.1 - 3.5e-45 154.6 0.0 4.6e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 EKX35994.1 - 1.6e-05 24.6 0.0 2.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_2 PF13379.6 EKX35994.1 - 2e-05 24.4 0.0 0.00016 21.5 0.0 2.1 2 0 0 2 2 2 1 NMT1-like family Hydrolase_4 PF12146.8 EKX35995.1 - 4.9e-68 229.0 0.0 5.8e-68 228.7 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EKX35995.1 - 1.3e-15 57.8 0.1 3.2e-12 46.7 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EKX35995.1 - 8.8e-12 46.1 0.0 1.2e-11 45.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 EKX35995.1 - 0.00022 20.2 0.0 0.00032 19.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 EKX35995.1 - 0.00041 19.9 0.0 0.54 9.7 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thioesterase PF00975.20 EKX35995.1 - 0.00069 19.8 0.1 0.0016 18.6 0.0 1.6 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_2 PF02230.16 EKX35995.1 - 0.00086 19.2 0.0 0.082 12.7 0.0 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase LIDHydrolase PF10230.9 EKX35995.1 - 0.0014 18.2 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.13 EKX35995.1 - 0.0014 18.5 0.0 0.0034 17.3 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EKX35995.1 - 0.0019 17.9 0.0 0.0046 16.6 0.0 1.8 1 1 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.7 EKX35995.1 - 0.0027 17.5 0.0 0.29 10.9 0.0 2.8 3 0 0 3 3 3 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 EKX35995.1 - 0.01 15.4 0.0 1 8.9 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) PGAP1 PF07819.13 EKX35995.1 - 0.014 15.2 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein LCAT PF02450.15 EKX35995.1 - 0.032 13.4 0.0 0.078 12.1 0.0 1.6 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase DUF2974 PF11187.8 EKX35995.1 - 0.048 13.2 0.0 0.077 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DLH PF01738.18 EKX35995.1 - 0.077 12.5 0.1 12 5.4 0.0 2.5 2 1 0 2 2 2 0 Dienelactone hydrolase family PseudoU_synth_2 PF00849.22 EKX35996.1 - 1.6e-11 44.5 0.0 3.8e-11 43.3 0.0 1.5 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 EKX35996.1 - 0.032 13.9 0.2 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 S4 domain Spin-Ssty PF02513.17 EKX35996.1 - 0.087 12.6 0.0 8.2 6.2 0.0 2.4 2 0 0 2 2 2 0 Spin/Ssty Family GARS_A PF01071.19 EKX35997.1 - 1.1e-17 64.5 0.0 2e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 EKX35997.1 - 3.4e-09 37.4 0.2 7e-09 36.4 0.2 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain ATP-grasp PF02222.22 EKX35997.1 - 0.00018 21.1 0.0 0.00034 20.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_C PF02843.16 EKX35997.1 - 0.011 16.0 0.0 0.082 13.2 0.0 2.3 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, C domain ATP-grasp_3 PF02655.14 EKX35997.1 - 0.04 14.0 0.0 0.12 12.4 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EKX35997.1 - 0.18 11.3 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus N6-adenineMlase PF10237.9 EKX35998.1 - 1e-37 129.4 0.0 1.4e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Aldedh PF00171.22 EKX35999.1 - 5.6e-154 513.1 0.1 6.9e-154 512.8 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Dak2 PF02734.17 EKX35999.1 - 0.22 11.4 2.4 0.47 10.3 2.4 1.5 1 0 0 1 1 1 0 DAK2 domain DUF2188 PF09954.9 EKX35999.1 - 0.62 10.2 0.0 0.62 10.2 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2188) Myb_DNA-binding PF00249.31 EKX36000.1 - 2.2e-35 120.6 7.9 1.1e-17 64.0 1.2 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX36000.1 - 2.7e-25 88.4 1.9 8.4e-17 61.2 0.3 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EKX36000.1 - 4e-06 26.6 0.2 0.042 13.7 0.0 2.1 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 EKX36000.1 - 0.016 15.2 0.1 0.14 12.1 0.0 2.1 2 1 0 2 2 2 0 SLIDE Rap1_C PF11626.8 EKX36000.1 - 0.021 14.9 0.6 1.7 8.8 0.6 2.1 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 EKX36000.1 - 0.19 11.9 1.8 0.56 10.4 0.2 2.3 1 1 0 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_4 PF13837.6 EKX36000.1 - 1.9 8.9 7.7 23 5.5 0.4 3.1 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain PDZ_6 PF17820.1 EKX36001.1 - 4.1e-09 36.2 0.3 1.4e-08 34.5 0.2 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX36001.1 - 3.1e-08 33.8 0.0 1.4e-07 31.7 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX36001.1 - 4.2e-07 30.2 0.0 8.2e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Acetyltransf_18 PF18014.1 EKX36001.1 - 0.065 13.1 0.4 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Tricorn_PDZ PF14685.6 EKX36001.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain Phycoerythr_ab PF02972.14 EKX36002.1 - 6.8e-30 102.7 0.9 9.1e-30 102.3 0.2 1.6 2 0 0 2 2 2 1 Phycoerythrin, alpha/beta chain TAT_signal PF10518.9 EKX36002.1 - 0.0032 17.2 0.5 0.0032 17.2 0.5 2.2 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence KAAG1 PF15354.6 EKX36002.1 - 0.017 15.7 0.2 0.026 15.1 0.2 1.4 1 0 0 1 1 1 0 Kidney-associated antigen 1 DUF4490 PF14892.6 EKX36004.1 - 4.3e-05 23.5 0.1 6.4e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) EF-hand_1 PF00036.32 EKX36004.1 - 0.011 15.2 0.1 0.4 10.3 0.0 2.6 2 0 0 2 2 2 0 EF hand EF-hand_10 PF14788.6 EKX36004.1 - 0.075 12.9 0.9 0.75 9.7 0.0 2.4 1 1 1 2 2 2 0 EF hand ATP1G1_PLM_MAT8 PF02038.16 EKX36005.1 - 0.066 12.7 0.2 0.066 12.7 0.2 2.8 2 1 0 2 2 2 0 ATP1G1/PLM/MAT8 family PDZ PF00595.24 EKX36006.1 - 1.1e-17 64.1 2.4 1.7e-10 41.1 0.3 2.5 2 0 0 2 2 2 2 PDZ domain SH3_1 PF00018.28 EKX36006.1 - 8.5e-12 44.5 0.0 1.8e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain PDZ_6 PF17820.1 EKX36006.1 - 1.3e-11 44.2 0.1 6.3e-06 25.9 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX36006.1 - 4.2e-09 36.6 1.1 0.00016 21.9 0.1 3.0 3 0 0 3 3 3 2 PDZ domain SH3_9 PF14604.6 EKX36006.1 - 9.5e-09 35.0 0.0 2.8e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EKX36006.1 - 3.7e-06 26.5 0.0 1.2e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain C2 PF00168.30 EKX36006.1 - 0.0003 21.0 0.0 0.00085 19.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain HALZ PF02183.18 EKX36006.1 - 0.037 14.3 0.3 0.074 13.3 0.3 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper ZapB PF06005.12 EKX36006.1 - 0.041 14.3 1.6 0.14 12.7 1.6 1.9 1 0 0 1 1 1 0 Cell division protein ZapB DUF1045 PF06299.12 EKX36006.1 - 0.064 13.2 0.3 0.14 12.1 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) NAD_binding_10 PF13460.6 EKX36007.1 - 0.00029 20.8 0.0 0.00045 20.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Hydrolase_3 PF08282.12 EKX36008.1 - 3.4e-43 148.2 0.0 2e-31 109.7 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EKX36008.1 - 6.6e-10 38.9 0.1 2e-07 30.8 0.0 2.9 2 1 1 3 3 3 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 EKX36008.1 - 1.2e-06 29.0 2.2 0.00026 21.4 0.1 2.7 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EKX36008.1 - 0.00011 22.6 0.4 0.016 15.6 0.0 2.9 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EKX36008.1 - 0.063 13.4 0.1 1.6 8.8 0.0 2.4 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase MIF4G_like PF09088.11 EKX36009.1 - 1.2e-36 126.3 0.0 2.6e-36 125.2 0.0 1.5 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 EKX36009.1 - 1.1e-30 107.1 9.7 1.7e-28 99.8 9.1 2.7 2 1 0 2 2 2 2 MIF4G like MIF4G PF02854.19 EKX36009.1 - 8.8e-08 32.0 0.2 2.2e-06 27.5 0.0 3.2 3 0 0 3 3 3 1 MIF4G domain DUF2052 PF09747.9 EKX36009.1 - 0.11 12.6 13.2 0.23 11.6 13.2 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 EKX36009.1 - 4.3 7.1 14.2 8.8 6.1 14.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 EKX36009.1 - 4.6 6.1 5.1 8.9 5.2 5.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 EKX36009.1 - 5.8 5.1 16.0 13 3.9 14.3 2.1 2 0 0 2 2 2 0 CDC45-like protein Aldo_ket_red PF00248.21 EKX36010.1 - 1.9e-44 152.0 0.0 1.8e-35 122.6 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family ClpS PF02617.17 EKX36011.1 - 2.4e-16 59.3 0.0 3.7e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS DUF1065 PF06358.11 EKX36013.1 - 0.014 15.3 0.5 0.034 14.1 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1065) IQ PF00612.27 EKX36014.1 - 1.5e-07 30.6 43.5 5.4 7.1 0.3 9.5 9 0 0 9 9 9 8 IQ calmodulin-binding motif Kelch_1 PF01344.25 EKX36015.1 - 6.9e-33 112.0 16.5 1.7e-07 30.7 0.2 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.15 EKX36015.1 - 8.6e-22 76.2 3.3 0.00011 22.1 0.0 6.6 6 1 1 7 7 7 4 Kelch motif Kelch_6 PF13964.6 EKX36015.1 - 1.8e-18 66.1 7.2 0.0018 18.5 0.1 6.2 3 1 3 6 6 6 4 Kelch motif Kelch_4 PF13418.6 EKX36015.1 - 5.8e-13 48.6 2.1 0.00094 19.1 0.0 5.3 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EKX36015.1 - 2.2e-07 30.7 10.4 0.00037 20.4 0.2 5.0 5 1 1 6 6 6 2 Kelch motif WYL_2 PF10902.8 EKX36015.1 - 0.002 18.5 0.0 2.1 8.8 0.0 2.4 2 0 0 2 2 2 2 WYL_2, Sm-like SH3 beta-barrel fold Kelch_3 PF13415.6 EKX36015.1 - 0.0036 17.6 10.7 0.0046 17.2 0.2 4.5 5 0 0 5 5 5 1 Galactose oxidase, central domain PQQ_3 PF13570.6 EKX36015.1 - 0.2 12.2 8.1 6.3 7.4 0.0 4.7 6 0 0 6 6 6 0 PQQ-like domain Ank_4 PF13637.6 EKX36016.1 - 1.5e-14 54.1 0.4 6.7e-10 39.3 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX36016.1 - 2.2e-10 40.5 1.3 0.0006 20.2 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EKX36016.1 - 2.1e-08 34.6 0.2 6.8e-08 33.0 0.2 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX36016.1 - 2.2e-06 27.6 0.3 0.092 13.4 0.1 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EKX36016.1 - 2.8e-06 27.5 1.3 0.00012 22.3 1.1 3.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) EF-hand_1 PF00036.32 EKX36017.1 - 5.3e-25 85.1 6.1 4.5e-06 25.8 0.1 4.7 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EKX36017.1 - 9.1e-21 74.1 10.2 1.4e-09 38.2 1.4 2.9 3 1 1 4 4 3 3 EF-hand domain pair EF-hand_8 PF13833.6 EKX36017.1 - 1.4e-18 66.5 7.9 3.5e-06 26.7 0.1 4.3 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EKX36017.1 - 3e-18 64.4 8.1 1.7e-05 24.1 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EKX36017.1 - 1.9e-17 61.6 7.2 0.00022 20.9 0.2 5.2 4 1 1 5 5 5 4 EF-hand domain RIIa PF02197.17 EKX36017.1 - 3.5e-11 42.6 0.1 6.6e-11 41.7 0.1 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit EF-hand_10 PF14788.6 EKX36017.1 - 2.9e-09 36.6 2.4 0.012 15.5 0.1 3.8 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 EKX36017.1 - 5e-08 32.8 4.7 0.0017 18.3 0.9 3.3 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EKX36017.1 - 1.7e-06 28.3 0.6 0.061 13.7 0.0 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region p25-alpha PF05517.12 EKX36017.1 - 0.053 13.7 0.4 3.5 7.8 0.0 2.2 1 1 0 2 2 2 0 p25-alpha S_100 PF01023.19 EKX36017.1 - 0.1 12.3 1.3 1.6 8.5 0.2 3.2 3 0 0 3 3 3 0 S-100/ICaBP type calcium binding domain CCD48 PF15799.5 EKX36017.1 - 0.11 10.8 0.0 0.72 8.1 0.0 1.9 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 48 DUF2385 PF09539.10 EKX36018.1 - 0.03 14.9 0.1 0.069 13.7 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2385) Duffy_binding PF05424.11 EKX36018.1 - 0.042 13.9 0.0 0.072 13.1 0.0 1.3 1 1 0 1 1 1 0 Duffy binding domain ChuX_HutX PF06228.13 EKX36019.1 - 0.00028 20.6 0.0 0.00042 20.1 0.0 1.2 1 0 0 1 1 1 1 Haem utilisation ChuX/HutX SRP-alpha_N PF04086.13 EKX36020.1 - 0.99 9.3 13.3 1.3 8.9 13.3 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF4875 PF16175.5 EKX36022.1 - 0.092 12.9 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4875) DivIC PF04977.15 EKX36022.1 - 0.12 12.2 0.1 0.12 12.2 0.1 2.3 2 1 1 3 3 3 0 Septum formation initiator GAS PF13851.6 EKX36022.1 - 0.2 11.0 7.0 1.1 8.6 7.0 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 EKX36022.1 - 0.6 10.3 3.3 1.9 8.7 3.0 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Sec2p PF06428.11 EKX36022.1 - 4.5 7.3 9.8 2.1 8.4 4.7 2.3 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p TPR_14 PF13428.6 EKX36023.1 - 1.2e-05 25.7 2.1 0.63 11.0 0.0 4.3 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX36023.1 - 7.7e-05 22.5 0.8 2.8 8.2 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX36023.1 - 0.0012 18.9 1.0 3.6 8.1 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX36023.1 - 0.0015 18.7 0.7 0.045 14.1 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX36023.1 - 0.0048 16.9 1.5 11 6.5 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX36023.1 - 0.0055 16.5 0.2 19 5.3 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX36023.1 - 0.29 11.0 4.0 16 5.6 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat dsDNA_bind PF01984.20 EKX36024.1 - 1.2e-33 115.7 9.7 1.4e-33 115.5 9.7 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain NDUF_B4 PF07225.12 EKX36024.1 - 0.059 13.3 0.1 0.074 12.9 0.1 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) EF-1_beta_acid PF10587.9 EKX36024.1 - 0.24 11.9 7.6 1.3 9.5 0.2 2.6 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region Fes1 PF08609.10 EKX36024.1 - 3 8.8 6.5 1.6 9.7 4.3 1.7 1 1 1 2 2 2 0 Nucleotide exchange factor Fes1 YolD PF08863.10 EKX36024.1 - 9.9 6.3 9.5 3.2 7.9 0.7 2.2 1 1 0 2 2 2 0 YolD-like protein RRM_1 PF00076.22 EKX36025.1 - 1.3e-20 73.0 0.4 1.6e-20 72.7 0.4 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EKX36025.1 - 6.2e-05 23.0 0.1 9.1e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif Limkain-b1 PF11608.8 EKX36025.1 - 0.0041 17.2 0.2 0.0069 16.4 0.2 1.4 1 0 0 1 1 1 1 Limkain b1 RRM_3 PF08777.11 EKX36025.1 - 0.0045 17.0 0.2 0.0071 16.4 0.2 1.4 1 1 0 1 1 1 1 RNA binding motif RRM_5 PF13893.6 EKX36025.1 - 0.0047 16.5 0.0 0.0062 16.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Exo_endo_phos PF03372.23 EKX36026.1 - 1e-14 54.7 0.0 1.2e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Methyltrn_RNA_2 PF04013.12 EKX36028.1 - 4.4e-15 55.9 0.0 1.9e-09 37.5 0.0 2.3 2 0 0 2 2 2 2 Putative SAM-dependent RNA methyltransferase Sel1 PF08238.12 EKX36029.1 - 8.1e-36 121.7 11.8 1.6e-05 25.4 0.1 10.0 11 0 0 11 11 11 8 Sel1 repeat DUF4055 PF13264.6 EKX36029.1 - 0.044 13.9 0.1 0.098 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) Na_H_Exchanger PF00999.21 EKX36030.1 - 4.7e-47 160.6 25.6 1.3e-46 159.1 16.7 2.1 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family Peptidase_C48 PF02902.19 EKX36031.1 - 1.1e-10 41.8 0.0 7.4e-08 32.5 0.1 2.5 1 1 1 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain Tetraspanin PF00335.20 EKX36031.1 - 0.0018 18.0 0.0 1.4 8.5 0.0 2.4 2 0 0 2 2 2 2 Tetraspanin family DUF1358 PF07096.11 EKX36031.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1358) DUF547 PF04784.14 EKX36032.1 - 6.2e-38 129.6 0.0 8.8e-38 129.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Abhydrolase_1 PF00561.20 EKX36033.1 - 1.8e-11 44.2 1.1 2.2e-11 43.9 1.1 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EKX36033.1 - 2.2e-09 37.0 0.2 2.4e-09 36.8 0.2 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EKX36033.1 - 4.5e-08 34.0 6.8 5.4e-08 33.7 6.8 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EKX36033.1 - 6e-06 26.5 0.3 7.5e-06 26.2 0.3 1.1 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 EKX36033.1 - 0.015 15.0 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 PGAP1-like protein Palm_thioest PF02089.15 EKX36033.1 - 0.026 14.3 0.0 0.028 14.2 0.0 1.0 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF676 PF05057.14 EKX36033.1 - 0.058 12.9 0.0 0.063 12.8 0.0 1.5 1 1 0 1 1 1 0 Putative serine esterase (DUF676) HIRA_B PF09453.10 EKX36033.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 HIRA B motif Abhydrolase_5 PF12695.7 EKX36033.1 - 0.16 11.7 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 EKX36033.1 - 0.18 11.6 0.2 0.19 11.6 0.2 1.2 1 0 0 1 1 1 0 Lipase (class 3) Pkinase_Tyr PF07714.17 EKX36034.1 - 1.8e-58 197.9 0.0 2e-58 197.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX36034.1 - 8.5e-28 97.4 0.0 9.5e-28 97.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EKX36034.1 - 0.071 12.4 2.2 0.34 10.2 2.2 1.9 1 1 0 1 1 1 0 Kinase-like DUF547 PF04784.14 EKX36035.1 - 3.5e-38 130.4 0.0 5.1e-38 129.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF547 SPC22 PF04573.12 EKX36037.1 - 3.6e-43 147.0 0.1 4.3e-43 146.8 0.1 1.1 1 0 0 1 1 1 1 Signal peptidase subunit SHOCT PF09851.9 EKX36038.1 - 0.0076 16.0 0.4 3.9 7.3 0.0 2.5 2 0 0 2 2 2 2 Short C-terminal domain DNA_ligase_aden PF01653.18 EKX36038.1 - 0.019 14.1 0.1 0.52 9.3 0.0 2.0 1 1 1 2 2 2 0 NAD-dependent DNA ligase adenylation domain Thioredoxin_4 PF13462.6 EKX36038.1 - 0.057 13.6 0.1 2.2 8.4 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin Terminase_GpA PF05876.12 EKX36038.1 - 0.14 10.7 2.7 0.32 9.5 1.2 2.0 2 0 0 2 2 2 0 Phage terminase large subunit (GpA) TMEM220 PF15071.6 EKX36039.1 - 5.3 7.8 6.1 27 5.6 6.1 2.3 1 1 0 1 1 1 0 Transmembrane family 220, helix PAP2_C PF14360.6 EKX36039.1 - 7.1 7.2 10.0 9.5 6.8 4.3 2.9 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Golgin_A5 PF09787.9 EKX36040.1 - 0.056 12.9 10.0 0.087 12.3 10.0 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF5320 PF17253.2 EKX36040.1 - 0.63 11.1 5.0 16 6.6 0.5 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5320) DUF1664 PF07889.12 EKX36040.1 - 0.83 9.7 7.1 3.2 7.8 6.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) G-gamma PF00631.22 EKX36040.1 - 1.5 8.9 5.4 1.5 8.9 1.7 2.4 1 1 1 2 2 2 0 GGL domain KxDL PF10241.9 EKX36040.1 - 1.6 9.1 10.2 2.2 8.6 3.7 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF16 PF01519.16 EKX36040.1 - 2.6 8.6 10.1 4.8 7.7 9.8 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 TMPIT PF07851.13 EKX36040.1 - 3.8 6.7 8.4 5.4 6.2 8.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein DivIC PF04977.15 EKX36040.1 - 6.5 6.6 8.3 2.1 8.2 1.3 2.5 1 1 1 2 2 2 0 Septum formation initiator GTP-bdg_M PF16360.5 EKX36040.1 - 8 7.1 8.3 2.9 8.5 4.7 2.2 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region PHD_like PF12910.7 EKX36041.1 - 0.01 15.9 0.9 3.8 7.5 0.2 2.1 1 1 1 2 2 2 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system Mvb12 PF09452.10 EKX36041.1 - 1.1 9.7 3.8 14 6.2 3.8 2.2 1 1 0 1 1 1 0 ESCRT-I subunit Mvb12 PP2C PF00481.21 EKX36042.1 - 2.4e-41 142.1 0.0 1.1e-39 136.7 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EKX36042.1 - 2.9e-05 23.8 0.1 0.22 11.2 0.0 2.7 1 1 1 2 2 2 2 Protein phosphatase 2C Na_H_Exchanger PF00999.21 EKX36044.1 - 2.6e-29 102.2 36.4 3.2e-29 101.9 36.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 EKX36044.1 - 1.1e-05 25.7 0.0 0.00064 20.0 0.0 2.4 1 1 0 1 1 1 1 TrkA-N domain DUF4267 PF14087.6 EKX36045.1 - 0.011 15.8 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4267) WD40 PF00400.32 EKX36046.1 - 1.7e-25 88.8 14.6 1.2e-08 35.5 0.5 4.2 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX36046.1 - 1.4e-06 28.5 0.7 0.0084 16.4 0.0 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF5046 PF16465.5 EKX36046.1 - 0.0046 16.5 0.0 2.5 7.4 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF5046) Ge1_WD40 PF16529.5 EKX36046.1 - 0.037 13.0 0.0 1.8 7.4 0.0 2.9 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PhoU PF01895.19 EKX36047.1 - 8.8 6.9 9.9 0.92 10.0 1.6 2.7 2 0 0 2 2 2 0 PhoU domain Ino80_Iec3 PF14612.6 EKX36048.1 - 0.0097 16.6 4.4 0.0097 16.6 4.4 1.7 1 1 1 2 2 2 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling SR-25 PF10500.9 EKX36048.1 - 0.04 13.5 22.7 0.075 12.6 15.1 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Dehydrin PF00257.19 EKX36048.1 - 0.78 10.3 10.6 0.43 11.1 8.8 1.5 1 1 0 1 1 1 0 Dehydrin GREB1 PF15782.5 EKX36048.1 - 8.4 3.4 14.3 10 3.1 14.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DEAD PF00270.29 EKX36049.1 - 1.1e-48 165.4 0.0 1.8e-48 164.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX36049.1 - 3.2e-08 33.9 0.1 1.7e-07 31.6 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX36049.1 - 1.4e-06 28.4 0.0 2e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EKX36049.1 - 0.00054 20.3 0.0 0.0016 18.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain CMS1 PF14617.6 EKX36049.1 - 0.00069 19.0 0.0 0.34 10.2 0.0 2.1 1 1 0 2 2 2 2 U3-containing 90S pre-ribosomal complex subunit SWI2_SNF2 PF18766.1 EKX36049.1 - 0.041 13.6 0.0 0.096 12.3 0.0 1.5 1 1 0 1 1 1 0 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 EKX36049.1 - 0.042 13.0 0.1 0.068 12.4 0.1 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Spec3 PF15795.5 EKX36050.1 - 2.4e-07 31.2 13.5 0.00051 20.5 0.8 2.1 1 1 1 2 2 2 2 Ectodermal ciliogenesis protein TM2 PF05154.16 EKX36050.1 - 0.74 10.2 11.3 2.2 8.7 4.2 2.1 2 0 0 2 2 2 0 TM2 domain TauD PF02668.16 EKX36051.1 - 1.1e-35 123.7 0.0 1.8e-35 123.1 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EKX36051.1 - 1.7e-11 44.6 0.4 3.3e-08 34.1 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF971) CsiD PF08943.10 EKX36051.1 - 0.044 12.9 0.0 0.081 12.0 0.0 1.4 1 0 0 1 1 1 0 CsiD Telomere_Sde2_2 PF13297.6 EKX36052.1 - 5.3e-19 67.6 0.2 9.7e-19 66.8 0.2 1.4 1 0 0 1 1 1 1 Telomere stability C-terminal DUF2781 PF10914.8 EKX36053.1 - 4.4e-39 134.2 8.1 4.9e-39 134.1 8.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) YecM PF06185.12 EKX36054.1 - 1.6e-31 109.3 0.0 8.3e-31 107.0 0.0 1.8 1 1 0 1 1 1 1 YecM protein Urm1 PF09138.11 EKX36055.1 - 3.3e-28 97.9 0.0 3.7e-28 97.7 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 EKX36055.1 - 2.7e-06 27.9 0.0 3.2e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 ThiS family DUF1640 PF07798.11 EKX36057.1 - 4e-05 23.7 3.5 5.9e-05 23.2 3.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Apolipoprotein PF01442.18 EKX36057.1 - 0.0018 18.2 1.8 0.0032 17.4 1.8 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF1664 PF07889.12 EKX36057.1 - 0.0079 16.2 1.7 0.037 14.1 1.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EKX36057.1 - 0.01 15.9 1.0 0.018 15.1 1.0 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CAF-1_p150 PF11600.8 EKX36057.1 - 0.013 15.2 6.8 0.02 14.6 6.8 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal OmpH PF03938.14 EKX36057.1 - 0.017 15.5 3.7 0.024 15.0 3.0 1.7 2 0 0 2 2 1 0 Outer membrane protein (OmpH-like) SHE3 PF17078.5 EKX36057.1 - 0.019 14.7 4.7 0.033 13.9 4.7 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 ApoLp-III PF07464.11 EKX36057.1 - 0.072 13.2 3.5 0.15 12.2 3.5 1.5 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) HMMR_N PF15905.5 EKX36057.1 - 0.072 12.6 7.8 0.12 11.8 7.8 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal ING PF12998.7 EKX36057.1 - 0.097 13.3 5.9 0.75 10.4 5.8 2.2 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Tox-ODYAM1 PF15642.6 EKX36057.1 - 0.1 11.5 1.9 0.14 11.1 1.9 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus TetR_C_37 PF18665.1 EKX36057.1 - 0.2 12.3 5.7 0.85 10.2 0.3 3.7 3 1 1 4 4 4 0 Tetracyclin repressor-like, C-terminal domain PIN_8 PF18476.1 EKX36057.1 - 0.25 11.1 4.4 0.43 10.4 4.4 1.3 1 0 0 1 1 1 0 PIN like domain COG5 PF10392.9 EKX36057.1 - 0.5 10.5 5.3 3.1 8.0 4.9 2.4 2 1 0 2 2 2 0 Golgi transport complex subunit 5 FeoB_Cyto PF17910.1 EKX36057.1 - 0.94 10.1 7.5 16 6.1 7.8 2.4 1 1 1 2 2 2 0 FeoB cytosolic helical domain DUF29 PF01724.16 EKX36057.1 - 1.1 9.5 5.7 22 5.3 5.2 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF29 COG2 PF06148.11 EKX36057.1 - 1.6 8.8 4.8 8.3 6.5 0.3 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HSCB_C PF07743.13 EKX36057.1 - 2.9 8.4 8.0 1.7e+02 2.7 8.0 2.6 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain Atg14 PF10186.9 EKX36057.1 - 3.7 6.5 8.5 6.2 5.8 8.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2203 PF09969.9 EKX36057.1 - 6.2 7.6 5.9 4.4 8.0 3.8 1.8 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2203) SOUL PF04832.12 EKX36058.1 - 2.1e-10 41.0 0.2 5.2e-10 39.7 0.0 1.7 2 0 0 2 2 2 1 SOUL heme-binding protein ATP-synt_B PF00430.18 EKX36058.1 - 0.0012 18.9 1.4 0.0019 18.3 1.4 1.2 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) ACBP PF00887.19 EKX36059.1 - 3.9e-21 75.1 0.0 6.5e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Exo_endo_phos PF03372.23 EKX36060.1 - 0.00018 21.1 0.0 0.00034 20.2 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_C48 PF02902.19 EKX36060.1 - 0.00035 20.5 0.5 0.0017 18.2 0.0 2.2 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Seipin PF06775.14 EKX36060.1 - 0.033 14.3 0.3 0.065 13.3 0.3 1.4 1 0 0 1 1 1 0 Putative adipose-regulatory protein (Seipin) RBM39linker PF15519.6 EKX36063.1 - 0.07 14.2 5.5 3.7 8.7 0.4 2.6 1 1 1 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein UPF0669 PF17065.5 EKX36063.1 - 0.098 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative cytokine, C6ORF120 DUF4662 PF15578.6 EKX36063.1 - 1.4 8.6 8.3 2.6 7.8 7.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4662) Motile_Sperm PF00635.26 EKX36064.1 - 2.3e-05 24.2 0.0 5.8e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 MSP (Major sperm protein) domain ApoLp-III PF07464.11 EKX36064.1 - 0.02 15.0 0.4 0.034 14.2 0.4 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Atg14 PF10186.9 EKX36064.1 - 0.53 9.3 5.5 0.71 8.9 5.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HAT_KAT11 PF08214.11 EKX36065.1 - 0.0007 19.0 0.0 0.0031 16.9 0.0 1.9 2 1 0 2 2 2 1 Histone acetylation protein DUF1974 PF09317.11 EKX36066.1 - 3.6e-52 177.7 0.0 9.2e-51 173.1 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1974) Acyl-CoA_dh_N PF02771.16 EKX36066.1 - 4.8e-18 65.9 0.0 1.2e-17 64.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EKX36066.1 - 2.1e-12 47.5 0.0 3.7e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EKX36066.1 - 8.7e-05 22.7 0.0 0.00016 21.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain SH2_2 PF14633.6 EKX36067.1 - 2.1e-27 96.0 0.2 8e-27 94.1 0.0 2.1 2 0 0 2 2 2 1 SH2 domain YqgF PF14639.6 EKX36067.1 - 8.7e-19 67.8 0.1 6.6e-18 64.9 0.0 2.4 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 EKX36067.1 - 5.5e-17 62.0 0.2 1.4e-16 60.7 0.2 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_9 PF17674.1 EKX36067.1 - 5e-07 30.5 0.2 3.4e-06 27.9 0.2 2.6 1 1 0 1 1 1 1 HHH domain Tex_YqgF PF16921.5 EKX36067.1 - 7.8e-07 29.6 0.0 1.6e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Tex protein YqgF-like domain HTH_44 PF14641.6 EKX36067.1 - 5.9e-06 26.7 0.7 5.9e-06 26.7 0.7 3.6 3 1 0 3 3 3 1 Helix-turn-helix DNA-binding domain of SPT6 Tex_N PF09371.10 EKX36067.1 - 9.9e-05 22.1 0.1 0.0011 18.7 0.1 2.5 1 1 0 1 1 1 1 Tex-like protein N-terminal domain SH2 PF00017.24 EKX36067.1 - 0.00035 20.6 0.0 0.0012 18.9 0.0 1.9 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.7 EKX36067.1 - 0.062 13.6 0.0 0.3 11.4 0.0 2.3 1 0 0 1 1 1 0 Helix-hairpin-helix motif Zn_clus PF00172.18 EKX36068.1 - 1.5e-05 25.0 8.2 1.5e-05 25.0 8.2 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain THF_DHG_CYH PF00763.23 EKX36070.1 - 2.2e-22 79.5 0.0 4.4e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 EKX36070.1 - 1.6e-17 63.2 0.2 3.9e-16 58.8 0.2 2.8 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 EKX36070.1 - 0.002 17.5 0.1 0.026 13.9 0.0 2.5 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MerR-DNA-bind PF09278.11 EKX36070.1 - 0.029 14.9 0.1 0.061 13.9 0.1 1.4 1 0 0 1 1 1 0 MerR, DNA binding DpaA_N PF16924.5 EKX36070.1 - 0.032 14.3 0.0 0.2 11.8 0.0 2.2 2 0 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain Ribosomal_S13_N PF08069.12 EKX36070.1 - 0.1 12.6 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain Glyco_transf_41 PF13844.6 EKX36071.1 - 6.3e-29 100.7 0.0 4.2e-24 84.8 0.0 2.0 2 0 0 2 2 2 2 Glycosyl transferase family 41 ECSIT PF06239.11 EKX36071.1 - 0.048 12.8 0.1 0.079 12.1 0.1 1.2 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway Glyco_trans_1_4 PF13692.6 EKX36071.1 - 0.049 14.1 0.0 0.28 11.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferases group 1 Glyco_tran_28_C PF04101.16 EKX36071.1 - 0.099 12.6 0.0 0.26 11.2 0.0 1.6 1 1 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain PAN_4 PF14295.6 EKX36072.1 - 1.7e-08 34.2 3.3 3.6e-08 33.2 3.3 1.6 1 0 0 1 1 1 1 PAN domain TPR_16 PF13432.6 EKX36072.1 - 3e-07 31.0 0.7 5.1e-07 30.2 0.7 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat PAN_1 PF00024.26 EKX36072.1 - 1.8e-05 24.6 0.2 3.2e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 PAN domain TPR_19 PF14559.6 EKX36072.1 - 0.0034 17.9 1.0 0.0054 17.2 1.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX36072.1 - 0.0046 17.0 2.7 0.056 13.6 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX36072.1 - 0.008 16.4 2.6 0.17 12.2 2.6 2.3 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_4 PF07721.14 EKX36072.1 - 0.0088 16.6 2.5 0.0088 16.6 2.5 2.4 3 0 0 3 3 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX36072.1 - 0.025 14.8 0.5 0.052 13.8 0.4 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EKX36072.1 - 0.032 15.0 3.9 0.92 10.5 0.4 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX36072.1 - 0.048 13.9 2.6 0.57 10.5 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hyd_65N_2 PF14498.6 EKX36072.1 - 0.097 12.5 0.3 0.14 11.9 0.3 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain TPR_10 PF13374.6 EKX36072.1 - 0.17 11.8 3.0 0.47 10.4 0.5 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SpoIIE PF07228.12 EKX36074.1 - 1.3e-12 48.1 0.4 5.2e-12 46.1 0.0 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EKX36074.1 - 1.3e-09 38.1 0.0 0.00011 21.9 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EKX36074.1 - 1.9e-06 27.7 0.0 3.2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SelK_SelG PF10961.8 EKX36074.1 - 0.033 14.8 5.6 0.065 13.9 5.6 1.5 1 0 0 1 1 1 0 Selenoprotein SelK_SelG DUF5629 PF18629.1 EKX36074.1 - 0.09 13.3 0.7 0.4 11.3 0.0 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5629) DER1 PF04511.15 EKX36075.1 - 1.4e-48 165.4 12.2 1.6e-48 165.2 12.2 1.0 1 0 0 1 1 1 1 Der1-like family GCV_T PF01571.21 EKX36076.1 - 1.9e-28 99.6 0.0 2.4e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain AAA_11 PF13086.6 EKX36077.1 - 6.7e-07 29.4 0.5 0.00079 19.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EKX36077.1 - 0.00059 19.6 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF2408 PF10303.9 EKX36077.1 - 0.002 18.7 0.4 0.0064 17.1 0.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) AAA PF00004.29 EKX36077.1 - 0.0026 18.2 0.2 0.0086 16.5 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EKX36077.1 - 0.0068 16.0 0.0 0.023 14.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF677 PF05055.12 EKX36077.1 - 0.008 15.1 0.1 0.018 14.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF677) Laminin_II PF06009.12 EKX36077.1 - 0.0098 15.9 11.8 0.38 10.8 2.0 2.4 1 1 1 2 2 2 2 Laminin Domain II MIS13 PF08202.11 EKX36077.1 - 0.012 14.9 7.4 0.019 14.3 7.4 1.2 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Baculo_PEP_C PF04513.12 EKX36077.1 - 0.016 15.2 1.3 0.058 13.4 0.8 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_30 PF13604.6 EKX36077.1 - 0.019 14.7 0.1 0.058 13.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 EKX36077.1 - 0.042 13.9 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain LUC7 PF03194.15 EKX36077.1 - 0.052 13.2 5.5 0.094 12.4 5.5 1.4 1 0 0 1 1 1 0 LUC7 N_terminus HAUS5 PF14817.6 EKX36077.1 - 0.055 12.2 6.6 0.08 11.7 6.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Tweety PF04906.13 EKX36077.1 - 0.056 12.1 0.9 0.094 11.4 0.9 1.3 1 0 0 1 1 1 0 Tweety AAA_7 PF12775.7 EKX36077.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ISG65-75 PF11727.8 EKX36077.1 - 0.06 12.6 2.5 0.11 11.8 2.5 1.4 1 0 0 1 1 1 0 Invariant surface glycoprotein Occludin_ELL PF07303.13 EKX36077.1 - 0.065 14.0 7.7 1.1 10.0 4.9 2.5 1 1 1 2 2 2 0 Occludin homology domain ApoLp-III PF07464.11 EKX36077.1 - 0.065 13.3 7.3 0.12 12.5 7.3 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF812 PF05667.11 EKX36077.1 - 0.075 11.9 8.5 0.11 11.3 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Ran-binding PF05508.11 EKX36077.1 - 0.081 11.9 4.3 0.15 11.0 4.3 1.4 1 0 0 1 1 1 0 RanGTP-binding protein Mt_ATP-synt_D PF05873.12 EKX36077.1 - 0.084 12.7 1.3 0.19 11.6 1.3 1.5 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Prominin PF05478.11 EKX36077.1 - 0.086 10.8 3.6 0.12 10.3 3.6 1.2 1 0 0 1 1 1 0 Prominin PilJ PF13675.6 EKX36077.1 - 0.097 12.7 0.5 0.24 11.4 0.5 1.6 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3584 PF12128.8 EKX36077.1 - 0.11 10.0 11.7 0.15 9.6 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Exonuc_VII_L PF02601.15 EKX36077.1 - 0.11 12.0 4.7 0.19 11.2 4.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit PIN_8 PF18476.1 EKX36077.1 - 0.12 12.2 3.3 0.19 11.6 3.3 1.2 1 0 0 1 1 1 0 PIN like domain LXG PF04740.12 EKX36077.1 - 0.12 12.1 4.1 0.2 11.3 4.1 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily YkyA PF10368.9 EKX36077.1 - 0.12 12.0 8.8 0.19 11.4 8.8 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein MCPsignal PF00015.21 EKX36077.1 - 0.13 12.1 2.1 0.22 11.3 2.1 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF745 PF05335.13 EKX36077.1 - 0.13 11.9 4.0 0.22 11.2 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) MobL PF18555.1 EKX36077.1 - 0.18 11.1 7.9 0.27 10.5 7.9 1.1 1 0 0 1 1 1 0 MobL relaxases FH2 PF02181.23 EKX36077.1 - 0.22 10.6 4.6 0.33 10.0 4.6 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain Fez1 PF06818.15 EKX36077.1 - 0.24 11.9 11.5 0.4 11.1 11.5 1.2 1 0 0 1 1 1 0 Fez1 TMPIT PF07851.13 EKX36077.1 - 0.24 10.6 6.2 0.39 9.9 6.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein ResIII PF04851.15 EKX36077.1 - 0.28 11.2 3.9 0.38 10.7 0.0 2.7 3 1 0 3 3 2 0 Type III restriction enzyme, res subunit LMBR1 PF04791.16 EKX36077.1 - 0.3 10.0 0.9 0.44 9.4 0.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein V_ATPase_I PF01496.19 EKX36077.1 - 0.37 8.7 3.5 0.59 8.0 3.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IFT57 PF10498.9 EKX36077.1 - 0.37 9.7 14.1 0.17 10.8 10.3 1.9 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF148 PF02520.17 EKX36077.1 - 0.38 10.9 6.4 0.71 10.0 6.4 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF148 EzrA PF06160.12 EKX36077.1 - 0.45 8.6 9.4 0.78 7.8 9.4 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Vps53_N PF04100.12 EKX36077.1 - 0.53 9.2 5.7 0.84 8.5 5.7 1.2 1 0 0 1 1 1 0 Vps53-like, N-terminal Sec34 PF04136.15 EKX36077.1 - 0.69 9.8 4.6 1.4 8.8 3.9 1.7 1 1 1 2 2 2 0 Sec34-like family DUF1451 PF07295.11 EKX36077.1 - 0.77 9.8 5.5 1.4 8.9 5.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain ABC_tran_CTD PF16326.5 EKX36077.1 - 0.89 9.8 6.0 2.6 8.4 6.0 1.8 1 0 0 1 1 1 0 ABC transporter C-terminal domain COG2 PF06148.11 EKX36077.1 - 0.93 9.6 9.3 1.7 8.7 8.8 1.8 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 ACCA PF03255.14 EKX36077.1 - 1.1 9.1 6.8 1.7 8.6 6.3 1.5 1 1 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit TPR_MLP1_2 PF07926.12 EKX36077.1 - 1.2 9.2 12.2 2 8.5 12.2 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Cauli_AT PF03233.13 EKX36077.1 - 1.2 9.0 10.4 0.65 9.9 6.2 2.1 1 1 1 2 2 2 0 Aphid transmission protein DUF1664 PF07889.12 EKX36077.1 - 1.2 9.2 15.5 4.5 7.3 3.1 2.6 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) ZapB PF06005.12 EKX36077.1 - 1.5 9.3 13.6 13 6.3 0.2 2.4 2 0 0 2 2 2 0 Cell division protein ZapB Herpes_UL6 PF01763.16 EKX36077.1 - 1.6 7.2 6.8 2.4 6.6 6.8 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Prefoldin PF02996.17 EKX36077.1 - 2.2 8.2 8.9 0.45 10.4 3.3 2.4 2 0 0 2 2 2 0 Prefoldin subunit DUF4533 PF15047.6 EKX36077.1 - 2.2 7.8 7.5 5.1 6.6 7.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) DUF948 PF06103.11 EKX36077.1 - 2.5 8.4 10.5 0.34 11.2 4.2 2.5 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) Phage_GP20 PF06810.11 EKX36077.1 - 2.8 7.8 11.0 6.8 6.5 10.8 1.6 1 1 0 1 1 1 0 Phage minor structural protein GP20 FlaG PF03646.15 EKX36077.1 - 2.8 8.2 10.8 8 6.7 10.8 1.8 1 0 0 1 1 1 0 FlaG protein DUF4407 PF14362.6 EKX36077.1 - 3.2 7.0 7.0 4.9 6.4 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) XhlA PF10779.9 EKX36077.1 - 3.2 8.0 13.5 0.78 10.0 3.0 3.2 2 1 1 3 3 3 0 Haemolysin XhlA DUF3958 PF13125.6 EKX36077.1 - 3.8 7.7 13.5 8.3 6.7 13.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) Syntaxin_2 PF14523.6 EKX36077.1 - 3.9 7.9 10.6 4.4 7.7 7.3 2.2 1 1 0 2 2 2 0 Syntaxin-like protein Fib_alpha PF08702.10 EKX36077.1 - 4.6 7.4 10.0 3 8.0 8.0 1.7 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family CdvA PF18822.1 EKX36077.1 - 4.8 7.0 14.3 7.4 6.4 7.4 2.3 1 1 1 2 2 2 0 CdvA-like coiled-coil domain Seryl_tRNA_N PF02403.22 EKX36077.1 - 5.1 7.4 12.3 3.6 7.8 8.4 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Apolipoprotein PF01442.18 EKX36077.1 - 5.2 6.9 14.2 8.9 6.1 14.2 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Cauli_DNA-bind PF03310.13 EKX36077.1 - 5.9 7.0 6.4 24 5.0 1.2 2.7 2 1 1 3 3 2 0 Caulimovirus DNA-binding protein OmpH PF03938.14 EKX36077.1 - 6.2 7.2 15.6 3.3 8.1 13.5 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) GAS PF13851.6 EKX36077.1 - 6.4 6.1 20.5 2.3 7.5 9.8 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4709 PF15821.5 EKX36077.1 - 7.6 6.9 10.3 84 3.5 10.3 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4709) Fmp27_WPPW PF10359.9 EKX36077.1 - 7.8 5.2 11.6 15 4.3 11.6 1.3 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4446 PF14584.6 EKX36077.1 - 9.1 6.3 8.0 3 7.8 4.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Uso1_p115_C PF04871.13 EKX36077.1 - 9.1 6.7 12.3 10 6.5 10.1 1.9 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region BLOC1_2 PF10046.9 EKX36077.1 - 9.7 6.6 9.6 53 4.2 4.9 3.2 2 1 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ada3 PF10198.9 EKX36078.1 - 0.013 15.6 0.1 0.018 15.2 0.1 1.1 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 Baculo_PEP_C PF04513.12 EKX36078.1 - 0.05 13.6 0.3 0.07 13.2 0.3 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus IpgD PF05925.12 EKX36078.1 - 0.2 10.2 0.0 0.26 9.8 0.0 1.0 1 0 0 1 1 1 0 Enterobacterial virulence protein IpgD DUF1664 PF07889.12 EKX36078.1 - 0.35 10.9 1.9 0.5 10.4 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Metal_resist PF13801.6 EKX36078.1 - 0.56 10.4 10.4 2.1 8.5 7.3 2.6 2 1 0 2 2 2 0 Heavy-metal resistance UreE_C PF05194.12 EKX36079.1 - 0.052 14.0 0.0 0.1 13.1 0.0 1.6 2 0 0 2 2 2 0 UreE urease accessory protein, C-terminal domain Ank_2 PF12796.7 EKX36081.1 - 7.1e-26 90.6 0.0 3e-12 47.0 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX36081.1 - 2.3e-25 88.6 0.1 5e-10 39.7 0.0 4.1 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX36081.1 - 2.4e-19 69.2 0.1 1.7e-09 37.7 0.1 2.6 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX36081.1 - 6.5e-17 61.1 0.6 0.00013 22.2 0.0 5.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 EKX36081.1 - 2.6e-16 58.1 0.1 6.6e-05 23.0 0.0 5.6 6 0 0 6 6 6 3 Ankyrin repeat DUF3734 PF12536.8 EKX36081.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Patatin phospholipase DUF1110 PF06533.12 EKX36081.1 - 0.12 12.3 0.0 3.7 7.5 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1110) Ank_4 PF13637.6 EKX36082.1 - 5.5e-18 65.1 0.2 6.5e-10 39.3 0.1 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX36082.1 - 1.6e-12 47.8 0.1 2e-12 47.5 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX36082.1 - 9.7e-10 38.5 0.2 2.3e-09 37.3 0.1 1.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX36082.1 - 8.7e-09 35.4 0.2 2.4e-07 30.9 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EKX36082.1 - 1.1e-07 31.5 0.1 9.2e-07 28.7 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 EKX36083.1 - 4.5e-16 59.2 0.0 1.2e-10 41.9 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX36083.1 - 3.3e-15 56.2 0.0 5.5e-06 26.8 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX36083.1 - 3e-13 49.6 0.0 3.9e-07 30.2 0.0 4.3 4 1 1 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EKX36083.1 - 3.4e-12 46.4 0.0 2.6e-07 30.8 0.0 2.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX36083.1 - 4.4e-10 38.9 0.2 0.00022 21.4 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat ABC_tran PF00005.27 EKX36084.1 - 3.9e-47 160.2 2.1 2e-25 89.9 0.4 4.3 2 2 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EKX36084.1 - 6.8e-13 48.6 2.0 0.00011 21.7 0.2 3.9 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EKX36084.1 - 1.6e-12 47.9 0.7 0.0049 16.7 0.0 4.3 2 2 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EKX36084.1 - 7.8e-07 28.7 0.0 0.052 13.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 EKX36084.1 - 1.3e-06 28.4 1.0 0.068 12.9 0.0 3.5 3 1 1 4 4 4 2 AAA ATPase domain MMR_HSR1 PF01926.23 EKX36084.1 - 8.2e-06 25.9 0.0 0.14 12.2 0.0 3.2 3 0 0 3 3 2 2 50S ribosome-binding GTPase DUF815 PF05673.13 EKX36084.1 - 1e-05 24.8 0.0 0.0046 16.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 EKX36084.1 - 2.3e-05 24.4 0.0 0.15 11.9 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EKX36084.1 - 2.6e-05 24.5 0.0 0.13 12.5 0.0 3.1 2 0 0 2 2 2 2 AAA domain Chromo PF00385.24 EKX36084.1 - 3.2e-05 23.8 2.6 9.1e-05 22.3 2.6 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA PF00004.29 EKX36084.1 - 3.4e-05 24.3 0.3 0.9 10.0 0.0 3.8 4 1 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EKX36084.1 - 4.3e-05 23.8 0.0 0.033 14.4 0.1 2.7 2 0 0 2 2 2 1 AAA domain 4HB PF17947.1 EKX36084.1 - 7.2e-05 22.8 0.0 0.00033 20.7 0.0 2.2 1 0 0 1 1 1 1 Four helical bundle domain AAA_16 PF13191.6 EKX36084.1 - 7.9e-05 23.1 0.0 0.18 12.2 0.0 3.0 3 0 0 3 3 2 1 AAA ATPase domain AAA_7 PF12775.7 EKX36084.1 - 0.00017 21.1 0.0 0.18 11.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 EKX36084.1 - 0.0002 21.5 0.0 0.96 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EKX36084.1 - 0.00039 20.8 0.0 0.53 10.7 0.0 2.6 2 0 0 2 2 2 1 RNA helicase MeaB PF03308.16 EKX36084.1 - 0.00059 18.9 0.1 0.54 9.2 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase_2 PF01637.18 EKX36084.1 - 0.00064 19.7 1.2 3.8 7.4 0.0 3.6 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea Dynamin_N PF00350.23 EKX36084.1 - 0.00076 19.6 0.3 0.075 13.1 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.6 EKX36084.1 - 0.0015 19.1 20.5 0.017 15.6 0.0 4.2 4 1 0 4 4 3 1 AAA domain AAA_18 PF13238.6 EKX36084.1 - 0.0027 18.2 0.0 3.6 8.1 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_27 PF13514.6 EKX36084.1 - 0.0051 16.4 0.1 1.1 8.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 EKX36084.1 - 0.0064 16.7 0.0 1.3 9.3 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EKX36084.1 - 0.0065 16.2 0.0 0.68 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EKX36084.1 - 0.0067 16.2 1.9 2.3 7.9 0.0 3.7 4 0 0 4 4 3 1 AAA domain AAA_14 PF13173.6 EKX36084.1 - 0.0078 16.3 0.0 3.4 7.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EKX36084.1 - 0.0086 15.3 0.0 2 7.5 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 EKX36084.1 - 0.0094 15.9 0.0 1.8 8.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Rad17 PF03215.15 EKX36084.1 - 0.011 15.7 0.0 3.9 7.4 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain TniB PF05621.11 EKX36084.1 - 0.013 14.9 0.1 0.22 10.9 0.0 2.7 3 0 0 3 3 3 0 Bacterial TniB protein G-alpha PF00503.20 EKX36084.1 - 0.017 14.3 0.5 2.3 7.3 0.1 2.8 3 0 0 3 3 3 0 G-protein alpha subunit Septin PF00735.18 EKX36084.1 - 0.034 13.4 0.0 5.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Septin ATP-synt_ab PF00006.25 EKX36084.1 - 0.04 13.6 0.0 0.65 9.6 0.1 2.6 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Vac14_Fab1_bd PF12755.7 EKX36084.1 - 0.049 14.2 0.0 1.7 9.3 0.0 2.8 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region Zeta_toxin PF06414.12 EKX36084.1 - 0.059 12.7 0.9 3.8 6.7 0.1 3.0 2 1 1 3 3 3 0 Zeta toxin DUF87 PF01935.17 EKX36084.1 - 0.068 13.2 5.0 4.6 7.3 0.1 3.7 4 0 0 4 4 3 0 Helicase HerA, central domain PRK PF00485.18 EKX36084.1 - 0.11 12.3 0.2 4.4 7.0 0.0 2.8 2 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family FeoB_N PF02421.18 EKX36084.1 - 0.12 11.9 0.1 8.7 5.9 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B 2OG-FeII_Oxy_3 PF13640.6 EKX36086.1 - 0.00011 23.0 0.0 0.00021 22.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily S4 PF01479.25 EKX36086.1 - 0.059 13.1 0.3 0.17 11.6 0.1 1.8 2 0 0 2 2 2 0 S4 domain DUF525 PF04379.14 EKX36087.1 - 9e-12 45.1 0.0 1.6e-10 41.1 0.0 2.3 1 1 0 1 1 1 1 ApaG domain F-box PF00646.33 EKX36087.1 - 0.031 14.2 0.0 0.073 13.0 0.0 1.6 1 0 0 1 1 1 0 F-box domain OmpA_membrane PF01389.17 EKX36087.1 - 0.15 11.8 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 OmpA-like transmembrane domain DegT_DnrJ_EryC1 PF01041.17 EKX36088.1 - 1.7e-57 195.4 0.0 2e-57 195.1 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EKX36088.1 - 2.9e-12 46.4 0.0 4.5e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EKX36088.1 - 0.0014 17.6 0.0 0.0063 15.5 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EKX36088.1 - 0.0021 16.6 0.0 0.0032 16.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 EKX36088.1 - 0.11 11.2 0.0 0.27 9.9 0.0 1.6 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain DUF4254 PF14063.6 EKX36089.1 - 0.00028 20.7 0.4 0.88 9.4 0.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF4254) Pex24p PF06398.11 EKX36089.1 - 0.23 10.4 1.1 0.32 9.9 1.1 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin CAP_N PF01213.19 EKX36090.1 - 0.26 10.8 6.9 0.4 10.1 6.9 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 EKX36090.1 - 0.82 9.7 7.5 2 8.5 7.5 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 MORN PF02493.20 EKX36091.1 - 9.1e-07 28.4 0.5 9.1e-07 28.4 0.5 4.3 3 1 1 4 4 4 3 MORN repeat Cupin_8 PF13621.6 EKX36092.1 - 2.4e-08 34.0 0.0 2.9e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EKX36092.1 - 1.4e-07 31.3 0.0 2e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 EKX36092.1 - 0.019 14.7 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Cupin domain JmjC PF02373.22 EKX36092.1 - 0.029 14.8 0.0 0.044 14.2 0.0 1.5 1 0 0 1 1 1 0 JmjC domain, hydroxylase Cupin_3 PF05899.12 EKX36092.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_1 PF00190.22 EKX36092.1 - 0.19 11.4 0.0 0.39 10.3 0.0 1.5 1 0 0 1 1 1 0 Cupin Pyr_redox_2 PF07992.14 EKX36093.1 - 1.8e-46 158.8 0.0 2.4e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EKX36093.1 - 3.1e-27 95.0 0.0 6.9e-27 93.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EKX36093.1 - 1.2e-16 61.0 0.8 4.7e-13 49.5 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EKX36093.1 - 4.5e-07 29.3 1.3 0.00023 20.4 3.2 2.8 2 1 1 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.6 EKX36093.1 - 2.8e-06 26.8 0.4 0.00039 19.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EKX36093.1 - 5.9e-05 22.5 0.0 0.0033 16.8 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 EKX36093.1 - 0.001 18.5 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EKX36093.1 - 0.0063 15.6 2.0 0.011 14.8 2.0 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 EKX36093.1 - 0.039 12.6 1.5 0.053 12.2 0.7 1.6 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 EKX36093.1 - 0.059 12.6 0.5 0.11 11.7 0.5 1.4 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 EKX36093.1 - 0.33 10.5 3.9 3.5 7.1 2.8 2.4 2 1 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EKX36093.1 - 4.6 7.6 5.2 7.4 6.9 2.4 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Ion_trans PF00520.31 EKX36094.1 - 5.2e-34 117.6 24.2 7.8e-34 117.0 24.2 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EKX36094.1 - 2.5e-06 26.4 21.2 5.2e-06 25.4 21.2 1.4 1 0 0 1 1 1 1 Polycystin cation channel EF-hand_7 PF13499.6 EKX36094.1 - 0.0038 17.6 0.7 0.012 16.0 0.6 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX36094.1 - 0.026 14.4 0.2 0.25 11.4 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain SPATA9 PF15824.5 EKX36094.1 - 0.049 12.9 0.1 0.08 12.2 0.1 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 9 FtsJ PF01728.19 EKX36095.1 - 1.9e-08 34.6 0.0 5.1e-08 33.2 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase RRM_1 PF00076.22 EKX36095.1 - 0.0051 16.6 0.0 0.0097 15.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_25 PF13649.6 EKX36095.1 - 0.072 13.8 0.0 0.16 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain ATP11 PF06644.11 EKX36099.1 - 5.7e-23 82.1 0.1 7e-23 81.8 0.1 1.0 1 0 0 1 1 1 1 ATP11 protein 2OG-FeII_Oxy_3 PF13640.6 EKX36100.1 - 2.3e-13 50.8 0.0 4.8e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EKX36100.1 - 8.3e-06 26.2 0.0 1.7e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 EKX36100.1 - 0.00032 21.3 0.0 0.00073 20.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Oxygenase-NA PF09859.9 EKX36100.1 - 0.043 13.3 0.0 0.14 11.7 0.0 1.8 1 1 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA BTB_2 PF02214.22 EKX36102.1 - 4.7e-14 52.5 0.0 9.7e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain TPR_2 PF07719.17 EKX36103.1 - 4e-15 54.6 0.1 0.0018 18.2 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EKX36103.1 - 6.1e-14 51.3 0.1 0.0001 22.4 0.0 4.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 EKX36103.1 - 4.6e-13 48.6 0.0 7.3e-06 25.6 0.0 4.3 4 0 0 4 4 4 2 TPR repeat TPR_19 PF14559.6 EKX36103.1 - 1e-12 48.3 5.2 6.5e-06 26.6 0.3 3.8 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX36103.1 - 4.7e-11 43.1 4.2 8.3e-05 23.2 0.0 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX36103.1 - 9.4e-11 41.1 0.1 0.056 13.3 0.0 5.4 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX36103.1 - 1e-10 41.5 7.7 0.029 15.2 0.0 5.3 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX36103.1 - 6.6e-10 38.4 0.4 0.22 11.8 0.1 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX36103.1 - 2.1e-07 31.1 15.6 0.079 13.3 0.7 5.5 2 2 4 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX36103.1 - 8.2e-06 26.1 3.6 15 6.5 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Coatomer_E PF04733.14 EKX36103.1 - 1e-05 25.1 0.3 0.009 15.5 0.0 3.0 1 1 2 3 3 3 1 Coatomer epsilon subunit TPR_9 PF13371.6 EKX36103.1 - 2.9e-05 24.1 6.9 0.053 13.7 0.1 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX36103.1 - 3.8e-05 23.8 0.4 0.0076 16.5 0.0 2.9 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 EKX36103.1 - 0.00016 20.7 0.4 2 7.2 0.0 3.0 1 1 2 3 3 3 2 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 EKX36103.1 - 0.00025 20.9 3.3 16 5.8 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EKX36103.1 - 0.00057 19.5 2.0 0.0098 15.5 0.1 2.9 1 1 2 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_10 PF13374.6 EKX36103.1 - 0.0012 18.6 11.5 2.4 8.1 0.1 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TAF1_subA PF14929.6 EKX36103.1 - 0.02 14.3 2.2 0.032 13.7 0.4 1.8 1 1 1 2 2 2 0 TAF RNA Polymerase I subunit A Castor_Poll_mid PF06241.12 EKX36104.1 - 0.0007 19.5 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Castor and Pollux, part of voltage-gated ion channel Ferrochelatase PF00762.19 EKX36104.1 - 0.022 13.8 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Ferrochelatase SR-25 PF10500.9 EKX36104.1 - 0.17 11.5 1.0 0.18 11.4 0.3 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ank_5 PF13857.6 EKX36105.1 - 0.035 14.4 0.0 0.069 13.5 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Augurin PF15187.6 EKX36105.1 - 0.73 10.0 4.9 0.95 9.7 3.9 1.6 2 0 0 2 2 2 0 Oesophageal cancer-related gene 4 SAM_1 PF00536.30 EKX36106.1 - 1.6e-06 28.4 0.0 3.8e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EKX36106.1 - 2.8e-05 24.2 0.1 0.00047 20.2 0.1 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Ank_3 PF13606.6 EKX36106.1 - 0.00035 20.8 0.0 0.00093 19.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 EKX36106.1 - 0.00051 20.3 0.0 0.00088 19.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX36106.1 - 0.014 15.8 0.0 0.032 14.7 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat Ank_2 PF12796.7 EKX36106.1 - 0.088 13.4 0.0 0.16 12.6 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) N-glycanase_C PF09113.10 EKX36110.1 - 0.097 12.5 0.7 0.18 11.6 0.7 1.4 1 0 0 1 1 1 0 Peptide-N-glycosidase F, C terminal PPP5 PF08321.12 EKX36111.1 - 2.5e-19 69.3 1.0 4e-19 68.7 0.4 1.6 1 1 1 2 2 2 1 PPP5 TPR repeat region Metallophos PF00149.28 EKX36111.1 - 9.9e-14 52.3 0.2 1.7e-13 51.5 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 EKX36111.1 - 3.5e-07 29.8 0.2 1.1e-06 28.2 0.3 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX36111.1 - 1.6e-06 27.8 0.5 3.9e-06 26.6 0.5 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX36111.1 - 0.00014 21.8 0.1 0.00032 20.7 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX36111.1 - 0.0016 19.1 0.1 0.0026 18.3 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX36111.1 - 0.002 18.8 0.0 0.014 16.2 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX36111.1 - 0.0036 16.9 0.3 0.0084 15.8 0.3 1.6 1 0 0 1 1 1 1 TPR repeat RRM_1 PF00076.22 EKX36112.1 - 3.3e-09 36.5 0.0 0.00014 21.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CUE PF02845.16 EKX36112.1 - 0.00028 20.5 0.4 0.0046 16.6 0.1 3.1 2 0 0 2 2 2 1 CUE domain Nup35_RRM_2 PF14605.6 EKX36112.1 - 0.035 14.1 0.1 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Transglut_i_TM PF14400.6 EKX36112.1 - 5.8 7.0 7.9 23 5.0 1.5 2.8 2 1 1 3 3 3 0 Inactive transglutaminase fused to 7 transmembrane helices BTG PF07742.12 EKX36113.1 - 2.5e-14 53.1 0.1 3.5e-14 52.6 0.1 1.3 1 0 0 1 1 1 1 BTG family PAM2 PF07145.15 EKX36113.1 - 0.025 14.3 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Peptidase_M23 PF01551.22 EKX36115.1 - 2.2e-08 34.2 0.1 3.4e-08 33.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M23 DEC-1_N PF04625.13 EKX36116.1 - 0.026 13.5 1.5 0.034 13.2 1.5 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF5486 PF17588.2 EKX36116.1 - 0.18 11.7 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5486) Pkinase PF00069.25 EKX36117.1 - 2.1e-27 96.1 0.0 1.4e-17 63.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EKX36117.1 - 2e-06 27.3 0.9 0.044 13.1 0.0 2.8 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 EKX36117.1 - 0.084 12.8 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Epimerase PF01370.21 EKX36119.1 - 9.7e-54 182.4 0.0 1.3e-53 181.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EKX36119.1 - 2e-16 60.3 0.1 5.5e-16 58.9 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EKX36119.1 - 1.4e-07 30.9 0.0 2.3e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EKX36119.1 - 2.5e-07 30.0 2.1 3e-06 26.5 2.1 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EKX36119.1 - 2.3e-06 27.0 0.9 0.00037 19.7 0.0 3.1 2 2 1 3 3 3 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EKX36119.1 - 1.8e-05 24.0 0.4 6.2e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein PHA_gran_rgn PF09650.10 EKX36119.1 - 0.18 12.1 0.0 1.2 9.5 0.0 2.3 3 0 0 3 3 3 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) DNA_ligase_ZBD PF03119.16 EKX36121.1 - 0.28 11.3 2.9 0.64 10.1 0.1 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Retrotrans_gag PF03732.17 EKX36122.1 - 0.0015 18.8 0.1 0.0015 18.8 0.1 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein FUSC PF04632.12 EKX36122.1 - 0.058 11.9 3.4 0.12 10.9 3.4 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-CCHC_4 PF14392.6 EKX36122.1 - 0.3 10.9 1.8 0.5 10.1 1.8 1.3 1 0 0 1 1 1 0 Zinc knuckle ALIX_LYPXL_bnd PF13949.6 EKX36127.1 - 0.0046 16.3 4.0 0.0066 15.8 4.0 1.1 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV NB-LRR PF12061.8 EKX36127.1 - 0.12 11.7 0.4 0.17 11.2 0.4 1.2 1 0 0 1 1 1 0 Late blight resistance protein R1 Baculo_PEP_C PF04513.12 EKX36130.1 - 0.27 11.3 41.6 1.2 9.1 1.7 9.4 8 2 2 10 10 10 0 Baculovirus polyhedron envelope protein, PEP, C terminus RNA_pol_N PF01194.17 EKX36131.1 - 0.096 13.0 0.4 0.16 12.3 0.4 1.4 1 0 0 1 1 1 0 RNA polymerases N / 8 kDa subunit BUD22 PF09073.10 EKX36132.1 - 1.8 7.9 12.9 2 7.6 12.9 1.1 1 0 0 1 1 1 0 BUD22 TNFR_c6 PF00020.18 EKX36133.1 - 0.00083 19.7 2.9 0.00083 19.7 2.9 22.4 15 6 8 23 23 23 12 TNFR/NGFR cysteine-rich region DUF1451 PF07295.11 EKX36136.1 - 0.0029 17.7 2.4 0.028 14.5 0.2 2.2 2 0 0 2 2 2 1 Zinc-ribbon containing domain Med8 PF10232.9 EKX36136.1 - 0.044 13.4 0.9 0.091 12.3 0.1 1.8 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 DUF883 PF05957.13 EKX36136.1 - 0.081 13.5 5.0 2.7 8.6 1.8 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Atrophin-1 PF03154.15 EKX36136.1 - 0.16 10.3 4.6 0.26 9.5 1.1 2.0 2 0 0 2 2 2 0 Atrophin-1 family PEP-utilisers_N PF05524.13 EKX36136.1 - 0.26 11.5 4.5 0.39 10.9 0.3 2.3 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF1764 PF08576.10 EKX36136.1 - 0.78 10.7 6.9 3.1 8.7 0.2 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) FKBP_N PF01346.18 EKX36136.1 - 5.7 8.0 8.5 17 6.4 0.7 2.3 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Terminase_4 PF05119.12 EKX36136.1 - 6.9 7.2 7.3 1.4 9.4 1.3 2.4 2 1 0 2 2 2 0 Phage terminase, small subunit RPN2_C PF18004.1 EKX36136.1 - 8.5 6.3 11.0 5.6 6.9 1.3 2.1 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain YtxH PF12732.7 EKX36136.1 - 9.8 6.8 10.2 0.93 10.1 3.2 2.2 2 0 0 2 2 2 0 YtxH-like protein Rsbr_N PF08678.10 EKX36138.1 - 0.24 11.4 5.6 0.32 11.1 1.1 2.3 2 0 0 2 2 2 0 Rsbr N terminal Corona_NS1 PF06145.11 EKX36140.1 - 0.21 11.1 3.2 6.7 6.3 0.3 2.5 2 0 0 2 2 2 0 Coronavirus nonstructural protein NS1 RE_NgoFVII PF09565.10 EKX36142.1 - 0.072 12.4 8.6 0.086 12.1 8.6 1.0 1 0 0 1 1 1 0 NgoFVII restriction endonuclease LRAT PF04970.13 EKX36142.1 - 2.8 8.3 5.6 4 7.8 5.6 1.4 1 1 0 1 1 1 0 Lecithin retinol acyltransferase Membralin PF09746.9 EKX36142.1 - 6 5.8 5.6 6.5 5.7 5.6 1.0 1 0 0 1 1 1 0 Tumour-associated protein Tma16 PF11176.8 EKX36146.1 - 0.013 15.4 0.5 0.014 15.3 0.5 1.1 1 0 0 1 1 1 0 Translation machinery-associated protein 16 DUF4862 PF16154.5 EKX36146.1 - 0.014 14.8 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4862) XhlA PF10779.9 EKX36146.1 - 0.041 14.1 0.3 0.25 11.6 0.1 1.9 2 0 0 2 2 2 0 Haemolysin XhlA CSF-1 PF05337.11 EKX36146.1 - 0.059 13.5 0.1 0.064 13.4 0.1 1.1 1 0 0 1 1 1 0 Macrophage colony stimulating factor-1 (CSF-1) PHM7_cyt PF14703.6 EKX36146.1 - 0.13 12.5 1.9 2.8 8.1 0.2 2.0 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Thymidylate_kin PF02223.17 EKX36147.1 - 0.0065 16.2 0.1 0.0079 15.9 0.1 1.2 1 0 0 1 1 1 1 Thymidylate kinase YedD PF13987.6 EKX36147.1 - 0.15 11.9 0.0 0.36 10.7 0.0 1.7 1 1 0 1 1 1 0 YedD-like protein Herpes_UL92 PF03048.14 EKX36148.1 - 3.5e-07 30.2 1.2 3.5e-07 30.2 1.2 2.3 2 0 0 2 2 2 1 UL92 family FGF-BP1 PF06473.12 EKX36149.1 - 0.039 13.8 0.5 0.055 13.3 0.5 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) ORC_WH_C PF18137.1 EKX36150.1 - 0.089 12.9 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal DUF92 PF01940.16 EKX36150.1 - 0.13 11.7 0.1 0.13 11.7 0.1 1.9 2 0 0 2 2 2 0 Integral membrane protein DUF92 mRNA_cap_enzyme PF01331.19 EKX36151.1 - 0.0082 16.0 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain Heliorhodopsin PF18761.1 EKX36153.1 - 6.5e-17 61.6 10.9 3.4e-14 52.8 0.6 2.8 2 0 0 2 2 2 2 Heliorhodopsin BAMBI PF06211.12 EKX36153.1 - 0.0074 16.5 0.1 0.033 14.4 0.1 2.2 1 0 0 1 1 1 1 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain RNase_H_2 PF13482.6 EKX36154.1 - 5.2e-15 55.8 0.8 1.9e-13 50.8 0.1 2.0 2 0 0 2 2 2 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 EKX36154.1 - 1e-07 31.9 0.0 0.0019 17.9 0.0 2.3 1 1 1 2 2 2 2 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_A_exo1 PF01612.20 EKX36154.1 - 0.00014 21.6 0.0 0.0002 21.1 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease DUF5051 PF16473.5 EKX36154.1 - 0.017 15.1 0.0 1.2 9.1 0.0 2.1 1 1 1 2 2 2 0 3' exoribonuclease, RNase T-like DNA_pol_B_exo1 PF03104.19 EKX36154.1 - 0.017 14.3 0.0 0.088 11.9 0.0 2.0 2 0 0 2 2 2 0 DNA polymerase family B, exonuclease domain DUF4672 PF15716.5 EKX36155.1 - 0.079 12.6 1.5 0.15 11.7 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) Phage_Gp15 PF06854.11 EKX36155.1 - 0.33 10.9 7.5 0.068 13.1 3.3 2.0 2 1 0 2 2 2 0 Bacteriophage Gp15 protein Vault_4 PF17796.1 EKX36156.1 - 0.17 12.0 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 Major Vault Protein repeat domain Ribul_P_3_epim PF00834.19 EKX36157.1 - 0.14 11.5 0.2 1.5 8.2 0.1 2.0 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family GBR_NSP5 PF17580.2 EKX36158.1 - 0.051 13.4 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 KMP11 PF03037.16 EKX36161.1 - 0.006 17.3 2.4 0.0081 16.9 2.2 1.4 1 1 0 1 1 1 1 Kinetoplastid membrane protein 11 SAPIS-gp6 PF16722.5 EKX36162.1 - 0.022 15.2 0.2 0.032 14.6 0.2 1.2 1 0 0 1 1 1 0 Pathogenicity island protein gp6 in Staphylococcus Ofd1_CTDD PF10637.9 EKX36162.1 - 0.043 13.2 0.1 0.043 13.2 0.1 1.1 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term zf-RING_2 PF13639.6 EKX36170.1 - 3.4 8.1 11.0 0.35 11.2 4.7 2.5 2 0 0 2 2 2 0 Ring finger domain Toxin_12 PF07740.12 EKX36171.1 - 0.011 16.4 0.1 0.017 15.8 0.1 1.2 1 0 0 1 1 1 0 Ion channel inhibitory toxin DX PF01666.17 EKX36171.1 - 0.028 14.9 0.0 0.038 14.5 0.0 1.2 1 0 0 1 1 1 0 DX module Tcp11 PF05794.13 EKX36173.1 - 8.8e-34 117.3 0.0 1.1e-32 113.7 0.0 2.6 1 1 0 1 1 1 1 T-complex protein 11 CHAD PF05235.14 EKX36173.1 - 0.31 11.0 3.9 11 5.9 1.9 3.4 2 1 1 3 3 3 0 CHAD domain TBP PF00352.21 EKX36174.1 - 7.6e-31 105.9 0.0 7.6e-15 54.6 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EKX36174.1 - 4.6e-06 26.7 0.0 0.077 13.1 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DcpS_C PF11969.8 EKX36179.1 - 1.4e-18 67.4 0.0 1.9e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF2711 PF10924.8 EKX36179.1 - 0.0055 16.3 0.0 0.013 15.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2711) DUF3877 PF12993.7 EKX36183.1 - 0.0017 18.2 0.4 0.002 18.0 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function, E. rectale Gene description (DUF3877) ACAS_N PF16177.5 EKX36183.1 - 0.083 12.8 0.0 0.2 11.6 0.0 1.6 2 0 0 2 2 2 0 Acetyl-coenzyme A synthetase N-terminus Stn1 PF10451.9 EKX36184.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Telomere regulation protein Stn1 Phage_H_T_join PF05521.11 EKX36186.1 - 0.066 13.7 0.7 2.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Phage head-tail joining protein Glyco_transf_17 PF04724.13 EKX36188.1 - 6.4e-27 94.5 0.1 7.1e-27 94.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 Glyco_tranf_2_4 PF13704.6 EKX36188.1 - 0.036 14.6 0.0 0.062 13.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Retrotrans_gag PF03732.17 EKX36189.1 - 0.0019 18.5 0.1 0.0073 16.6 0.1 2.0 1 0 0 1 1 1 1 Retrotransposon gag protein Kisspeptin PF15152.6 EKX36189.1 - 0.11 13.3 0.1 15 6.4 0.0 2.6 2 0 0 2 2 2 0 Kisspeptin IZUMO PF15005.6 EKX36189.1 - 0.19 12.3 1.5 0.37 11.3 0.3 2.1 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated RVT_2 PF07727.14 EKX36190.1 - 0.0015 18.2 0.0 0.0017 18.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNA_pol_N PF01194.17 EKX36193.1 - 0.082 13.2 0.2 0.28 11.5 0.2 1.9 1 0 0 1 1 1 0 RNA polymerases N / 8 kDa subunit PHC2_SAM_assoc PF16616.5 EKX36193.1 - 1.7 9.5 5.7 5.8 7.8 4.3 2.5 1 1 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 DUF4780 PF16012.5 EKX36195.1 - 0.0077 15.7 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4780) DUF5056 PF16479.5 EKX36195.1 - 0.49 10.7 3.1 0.74 10.1 1.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5056) DUF1011 PF06237.12 EKX36195.1 - 0.54 10.6 5.0 40 4.6 4.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1011) SYCE1 PF15233.6 EKX36197.1 - 0.0009 19.3 6.8 0.002 18.2 6.8 1.5 1 1 0 1 1 1 1 Synaptonemal complex central element protein 1 DivIC PF04977.15 EKX36197.1 - 0.0015 18.2 3.8 0.018 14.8 0.2 2.2 1 1 0 2 2 2 1 Septum formation initiator Occludin_ELL PF07303.13 EKX36197.1 - 0.0099 16.6 2.1 0.015 16.0 1.5 1.6 1 1 0 1 1 1 1 Occludin homology domain Rootletin PF15035.6 EKX36197.1 - 0.011 15.8 2.3 0.014 15.5 2.3 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion BRE1 PF08647.11 EKX36197.1 - 0.027 14.5 0.4 0.027 14.5 0.4 2.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase YabA PF06156.13 EKX36197.1 - 0.059 14.0 2.6 0.073 13.7 2.6 1.2 1 0 0 1 1 1 0 Initiation control protein YabA SAS4 PF15460.6 EKX36197.1 - 0.059 13.5 3.6 1.7 8.8 0.1 2.3 1 1 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 DUF1664 PF07889.12 EKX36197.1 - 0.074 13.1 2.3 0.11 12.6 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FapA PF03961.13 EKX36197.1 - 0.094 11.3 2.4 0.1 11.2 2.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A AlkA_N PF06029.11 EKX36197.1 - 0.11 12.8 0.6 0.86 9.9 0.1 2.0 1 1 1 2 2 2 0 AlkA N-terminal domain Prefoldin PF02996.17 EKX36197.1 - 0.13 12.2 5.7 3.6 7.5 0.2 2.3 2 0 0 2 2 2 0 Prefoldin subunit Nsp1_C PF05064.13 EKX36197.1 - 0.16 11.8 2.7 0.25 11.2 1.7 1.7 1 1 1 2 2 2 0 Nsp1-like C-terminal region Snapin_Pallidin PF14712.6 EKX36197.1 - 0.2 12.1 4.7 1.7 9.1 3.3 2.4 1 1 1 2 2 2 0 Snapin/Pallidin ZapB PF06005.12 EKX36197.1 - 0.25 11.8 5.6 0.72 10.3 0.1 2.2 1 1 1 2 2 2 0 Cell division protein ZapB APG6_N PF17675.1 EKX36197.1 - 0.31 11.6 10.5 0.25 11.9 4.8 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region TMF_DNA_bd PF12329.8 EKX36197.1 - 0.56 10.2 9.4 3.4 7.7 3.1 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SPX PF03105.19 EKX36197.1 - 0.72 9.7 5.0 3.6 7.4 5.0 1.8 1 1 0 1 1 1 0 SPX domain NADH_B2 PF14813.6 EKX36198.1 - 0.055 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Ephrin_rec_like PF07699.13 EKX36200.1 - 1.2e-06 28.2 3.7 1.2e-06 28.2 3.7 5.7 3 1 2 5 5 5 2 Putative ephrin-receptor like hEGF PF12661.7 EKX36200.1 - 0.11 13.2 3.4 0.11 13.2 3.4 7.0 9 1 0 9 9 9 0 Human growth factor-like EGF NCD3G PF07562.14 EKX36200.1 - 0.21 11.6 0.3 0.21 11.6 0.3 5.1 3 1 1 4 4 4 0 Nine Cysteines Domain of family 3 GPCR zf-C2H2_11 PF16622.5 EKX36200.1 - 2.4 8.0 7.8 1.8 8.4 0.2 3.7 2 1 1 3 3 3 0 zinc-finger C2H2-type TNFR_c6 PF00020.18 EKX36200.1 - 2.5 8.6 37.8 0.87 10.0 0.6 6.2 4 2 0 4 4 4 0 TNFR/NGFR cysteine-rich region Ephrin_rec_like PF07699.13 EKX36201.1 - 1.2e-14 53.8 100.1 4.1e-08 32.9 6.8 24.5 9 7 16 27 27 27 17 Putative ephrin-receptor like Ephrin_rec_like PF07699.13 EKX36202.1 - 3e-14 52.5 48.5 5.7e-05 22.8 1.6 6.9 4 3 3 7 7 7 6 Putative ephrin-receptor like Histone PF00125.24 EKX36203.1 - 2.4e-47 160.5 0.9 3.3e-47 160.1 0.9 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EKX36203.1 - 0.00055 20.0 0.0 0.0009 19.3 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EKX36203.1 - 0.0038 17.6 0.0 0.0063 16.9 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein SRCR PF00530.18 EKX36204.1 - 5.4e-17 62.1 1.8 1e-16 61.3 1.8 1.5 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Collagen PF01391.18 EKX36204.1 - 4.7e-14 51.9 61.9 1.3e-08 34.4 30.9 2.6 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) SRCR_2 PF15494.6 EKX36204.1 - 3e-05 24.5 0.2 0.00012 22.5 0.0 1.9 2 0 0 2 2 2 1 Scavenger receptor cysteine-rich domain BUD22 PF09073.10 EKX36204.1 - 0.015 14.7 0.2 0.019 14.4 0.2 1.1 1 0 0 1 1 1 0 BUD22 Syntaxin PF00804.25 EKX36204.1 - 0.024 14.3 1.2 0.037 13.7 1.2 1.2 1 0 0 1 1 1 0 Syntaxin ApoO PF09769.9 EKX36204.1 - 0.23 11.4 0.3 0.39 10.7 0.3 1.3 1 0 0 1 1 1 0 Apolipoprotein O RCC1 PF00415.18 EKX36205.1 - 4.9e-56 187.2 14.3 8.3e-12 45.5 0.2 7.2 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX36205.1 - 6e-34 115.2 27.2 7e-07 28.9 0.9 6.3 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Kelch_2 PF07646.15 EKX36205.1 - 0.018 15.0 0.1 21 5.3 0.0 4.0 4 0 0 4 4 4 0 Kelch motif DUF1921 PF09081.10 EKX36205.1 - 0.074 13.3 3.6 0.15 12.3 0.3 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1921) HSP70 PF00012.20 EKX36206.1 - 3.5e-131 438.3 0.0 1.5e-130 436.2 0.0 1.7 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EKX36206.1 - 1.5e-13 50.3 0.0 3.9e-13 48.9 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein DUF2407 PF10302.9 EKX36207.1 - 1.4 9.6 5.6 1.7 9.2 3.1 2.5 1 1 0 2 2 2 0 DUF2407 ubiquitin-like domain Cnd1 PF12717.7 EKX36207.1 - 2.8 8.0 6.6 5.9 6.9 6.6 1.6 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 GHL15 PF14885.6 EKX36207.1 - 4.2 7.3 7.0 0.89 9.5 2.7 2.1 1 1 1 2 2 2 0 Hypothetical glycosyl hydrolase family 15 fn2 PF00040.19 EKX36208.1 - 0.066 13.5 0.2 0.15 12.3 0.2 1.5 1 0 0 1 1 1 0 Fibronectin type II domain DUF1796 PF08795.10 EKX36208.1 - 0.37 10.7 2.0 2.1 8.3 0.2 3.2 2 0 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) HP_OMP PF01856.17 EKX36211.1 - 0.1 12.7 1.6 0.13 12.3 1.3 1.3 1 1 0 1 1 1 0 Helicobacter outer membrane protein DUF4199 PF13858.6 EKX36211.1 - 1.6 9.1 22.7 37 4.7 22.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Glyco_trans_1_4 PF13692.6 EKX36212.1 - 3e-12 47.1 0.0 2.4e-09 37.7 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EKX36212.1 - 0.004 16.7 0.0 0.018 14.6 0.0 1.9 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EKX36212.1 - 0.17 12.3 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 SDA1 PF05285.12 EKX36213.1 - 4.3e-05 23.1 34.5 5.9e-05 22.7 34.5 1.2 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 EKX36213.1 - 0.0028 16.0 29.5 0.0041 15.5 29.5 1.2 1 0 0 1 1 1 1 CDC45-like protein TFIIA PF03153.13 EKX36213.1 - 0.0053 16.8 22.4 0.0063 16.6 22.4 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF2151 PF10221.9 EKX36213.1 - 0.0077 14.9 8.4 0.011 14.4 8.4 1.1 1 0 0 1 1 1 1 Cell cycle and development regulator SAPS PF04499.15 EKX36213.1 - 0.0093 14.8 12.3 0.011 14.6 12.3 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Mpp10 PF04006.12 EKX36213.1 - 0.03 12.8 37.1 0.04 12.4 37.1 1.1 1 0 0 1 1 1 0 Mpp10 protein Na_trans_assoc PF06512.13 EKX36213.1 - 0.071 13.4 19.0 0.093 13.0 19.0 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.12 EKX36213.1 - 0.39 8.9 46.0 0.5 8.5 46.0 1.1 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.22 EKX36213.1 - 0.85 8.8 10.1 1.2 8.3 10.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SpoIIP PF07454.11 EKX36213.1 - 0.93 8.9 10.9 1.6 8.1 10.9 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CCSAP PF15748.5 EKX36213.1 - 2 8.5 11.8 3.6 7.7 11.8 1.4 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Presenilin PF01080.17 EKX36213.1 - 2.1 7.0 11.7 2.8 6.6 11.7 1.1 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 EKX36213.1 - 2.2 8.7 11.1 4.8 7.6 11.1 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF913 PF06025.12 EKX36213.1 - 2.4 7.1 11.0 3.4 6.5 11.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF1754 PF08555.10 EKX36213.1 - 4.1 8.3 21.2 9 7.2 21.2 1.6 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) DUF2076 PF09849.9 EKX36213.1 - 4.2 7.3 17.3 6.1 6.8 17.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SpoIIIAH PF12685.7 EKX36213.1 - 4.2 7.1 17.1 7.7 6.3 17.1 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein HMG_box PF00505.19 EKX36214.1 - 1.5e-16 60.6 0.1 1.6e-16 60.4 0.1 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EKX36214.1 - 8.1e-11 42.4 0.1 9.6e-11 42.1 0.1 1.1 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 EKX36214.1 - 0.00078 19.4 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 CHDNT (NUC034) domain DUF2280 PF10045.9 EKX36214.1 - 0.089 13.1 0.1 0.1 12.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2280) PDZ_2 PF13180.6 EKX36215.1 - 0.0048 17.2 0.0 0.0095 16.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX36215.1 - 0.067 13.5 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 PDZ domain DUF4303 PF14136.6 EKX36215.1 - 0.1 12.3 0.2 0.15 11.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) Sulfotransfer_2 PF03567.14 EKX36217.1 - 0.0052 16.7 0.1 0.11 12.4 0.1 2.2 1 1 0 1 1 1 1 Sulfotransferase family Pro_dh PF01619.18 EKX36218.1 - 8.1e-80 268.5 0.2 5.1e-79 265.9 0.2 1.9 1 1 0 1 1 1 1 Proline dehydrogenase EF-hand_6 PF13405.6 EKX36218.1 - 1.4e-06 27.7 0.1 0.00011 21.9 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 EKX36218.1 - 7.2e-06 26.4 0.1 1.7e-05 25.1 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX36218.1 - 1.5e-05 24.2 0.1 0.00076 18.9 0.0 2.6 2 0 0 2 2 2 1 EF hand AP_endonuc_2 PF01261.24 EKX36218.1 - 0.013 15.0 0.0 0.028 13.9 0.0 1.6 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel EF-hand_5 PF13202.6 EKX36218.1 - 0.017 14.6 1.9 0.041 13.4 0.2 2.4 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 EKX36218.1 - 0.039 13.8 1.8 0.41 10.5 0.1 2.9 2 1 1 3 3 3 0 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX36218.1 - 0.053 13.8 0.0 0.18 12.1 0.0 1.9 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region PTE PF02126.18 EKX36218.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotriesterase family LRIF1 PF15741.5 EKX36219.1 - 0.0009 17.9 9.8 0.0011 17.7 9.8 1.0 1 0 0 1 1 1 1 Ligand-dependent nuclear receptor-interacting factor 1 GrpE PF01025.19 EKX36219.1 - 0.18 11.4 8.3 0.25 11.0 8.3 1.1 1 0 0 1 1 1 0 GrpE Trns_repr_metal PF02583.17 EKX36219.1 - 0.28 11.6 5.2 0.078 13.3 2.0 1.7 2 0 0 2 2 2 0 Metal-sensitive transcriptional repressor V_ATPase_I PF01496.19 EKX36219.1 - 0.33 8.8 5.5 0.39 8.6 5.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_13 PF13166.6 EKX36219.1 - 0.62 8.6 10.6 0.74 8.4 10.6 1.1 1 0 0 1 1 1 0 AAA domain DUF2203 PF09969.9 EKX36219.1 - 1.2 9.9 7.8 3.3 8.4 2.2 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Nucleocapsid-N PF11030.8 EKX36220.1 - 0.017 15.1 0.1 0.031 14.2 0.1 1.4 1 0 0 1 1 1 0 Nucleocapsid protein N DUF4604 PF15377.6 EKX36221.1 - 0.018 15.5 12.6 0.023 15.1 12.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Trp_dioxygenase PF03301.13 EKX36221.1 - 0.2 10.9 4.2 0.22 10.8 4.2 1.0 1 0 0 1 1 1 0 Tryptophan 2,3-dioxygenase LsmAD PF06741.13 EKX36221.1 - 0.59 10.7 5.8 11 6.7 1.2 2.3 2 0 0 2 2 2 0 LsmAD domain Cullin PF00888.22 EKX36222.1 - 2.4e-175 584.7 10.3 3.4e-175 584.2 10.3 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EKX36222.1 - 1.9e-26 91.9 3.0 9.6e-26 89.6 3.0 2.4 1 0 0 1 1 1 1 Cullin protein neddylation domain RGS-like PF09128.11 EKX36222.1 - 1.1 8.9 8.7 0.27 10.9 2.3 2.6 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain Mpp10 PF04006.12 EKX36223.1 - 0.56 8.6 42.4 0.6 8.5 42.4 1.1 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 EKX36223.1 - 1.4 7.0 50.1 1.5 7.0 50.1 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EKX36223.1 - 2.5 6.1 53.9 3.5 5.6 53.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF3283 PF11686.8 EKX36227.1 - 0.0075 16.1 0.6 0.26 11.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3283) IGF2_C PF08365.11 EKX36227.1 - 0.32 11.0 0.1 0.32 11.0 0.1 2.5 3 1 0 3 3 3 0 Insulin-like growth factor II E-peptide Pribosyltran_N PF13793.6 EKX36228.1 - 1.2e-41 141.3 0.1 3.6e-40 136.5 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EKX36228.1 - 2.4e-20 73.4 2.9 4.7e-20 72.4 2.9 1.5 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EKX36228.1 - 1.1e-10 41.3 0.2 2.4e-10 40.1 0.2 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EKX36228.1 - 0.0033 16.9 0.0 0.015 14.7 0.0 2.1 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase Lipase_3 PF01764.25 EKX36229.1 - 1.3e-07 31.6 0.0 2.5e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EKX36229.1 - 0.004 17.8 0.9 0.0057 17.3 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2974 PF11187.8 EKX36229.1 - 0.013 15.0 0.2 0.19 11.3 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2974) UPF0227 PF05728.12 EKX36229.1 - 0.044 13.7 0.0 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.13 EKX36229.1 - 0.091 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein zinc_ribbon_5 PF13719.6 EKX36230.1 - 3.1 7.6 7.0 0.85 9.4 0.4 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DUF2070 PF09843.9 EKX36231.1 - 0.093 11.0 0.0 0.1 10.9 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Zn_clus PF00172.18 EKX36232.1 - 4.6e-13 49.0 31.4 2.7e-06 27.4 8.9 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain HSP90 PF00183.18 EKX36233.1 - 5.6e-33 114.6 1.4 5.6e-33 114.6 1.4 1.8 2 0 0 2 2 2 1 Hsp90 protein HSP90 PF00183.18 EKX36234.1 - 1.3e-200 667.7 72.8 4.8e-200 665.8 72.8 2.4 1 1 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EKX36234.1 - 3.5e-14 53.3 0.2 8.3e-14 52.0 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EKX36234.1 - 3.3e-12 46.4 0.3 1.2e-11 44.6 0.3 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CobT PF06213.12 EKX36234.1 - 0.0011 18.4 9.5 0.0011 18.4 9.5 3.8 4 0 0 4 4 4 3 Cobalamin biosynthesis protein CobT Sigma70_ner PF04546.13 EKX36234.1 - 3 7.7 59.5 0.043 13.7 13.2 4.8 5 0 0 5 5 5 0 Sigma-70, non-essential region Zn_clus PF00172.18 EKX36235.1 - 1.2e-05 25.3 15.4 1.2e-05 25.3 15.4 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Exo_endo_phos PF03372.23 EKX36236.1 - 9.5e-05 22.0 0.0 0.00017 21.2 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 EKX36237.1 - 6.1e-21 74.3 2.3 0.00046 20.9 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX36237.1 - 6.6e-11 42.4 0.2 0.027 14.7 0.0 4.6 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EKX36237.1 - 0.00068 19.6 0.0 0.03 14.2 0.0 2.7 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EKX36237.1 - 0.0027 17.1 0.0 0.0064 15.9 0.0 1.6 2 0 0 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 EKX36237.1 - 0.0043 16.1 0.0 0.06 12.3 0.0 2.4 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EKX36237.1 - 0.047 13.6 2.2 6.2 6.9 0.0 4.1 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat LisH_TPL PF17814.1 EKX36237.1 - 0.069 12.8 0.1 0.17 11.5 0.1 1.7 1 0 0 1 1 1 0 LisH-like dimerisation domain PUA_3 PF17785.1 EKX36237.1 - 0.089 12.6 0.0 9.6 6.1 0.0 2.4 2 0 0 2 2 2 0 PUA-like domain MPDZ_u10 PF16667.5 EKX36238.1 - 0.12 13.3 0.2 0.12 13.3 0.2 3.9 4 1 1 5 5 5 0 Unstructured region 10 on multiple PDZ protein Laminin_II PF06009.12 EKX36238.1 - 1.1 9.3 13.6 0.47 10.5 5.3 3.1 2 1 1 4 4 4 0 Laminin Domain II DUF1664 PF07889.12 EKX36238.1 - 1.3 9.1 12.4 4.3 7.4 5.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF745 PF05335.13 EKX36238.1 - 2.8 7.6 30.0 0.83 9.4 10.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF745) DUF1043 PF06295.12 EKX36238.1 - 4.7 7.2 16.9 6 6.9 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) ZapB PF06005.12 EKX36239.1 - 0.022 15.2 5.4 0.022 15.2 5.4 1.8 2 0 0 2 2 2 0 Cell division protein ZapB Sec34 PF04136.15 EKX36239.1 - 0.1 12.5 3.0 0.12 12.2 1.9 1.6 1 1 0 2 2 2 0 Sec34-like family DUF948 PF06103.11 EKX36239.1 - 0.13 12.6 0.2 0.23 11.7 0.2 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Nup88 PF10168.9 EKX36239.1 - 0.28 8.9 4.1 0.4 8.5 4.1 1.1 1 0 0 1 1 1 0 Nuclear pore component Seryl_tRNA_N PF02403.22 EKX36239.1 - 0.3 11.3 5.3 0.36 11.1 3.8 1.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Pup PF05639.11 EKX36239.1 - 0.48 11.4 3.1 0.66 10.9 1.8 1.9 2 0 0 2 2 2 0 Pup-like protein DivIC PF04977.15 EKX36239.1 - 1.9 8.3 4.8 3.9 7.3 4.8 1.5 1 0 0 1 1 1 0 Septum formation initiator DEAD PF00270.29 EKX36241.1 - 6.5e-44 149.8 0.0 9e-44 149.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX36241.1 - 9.5e-24 83.9 0.0 2.1e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EKX36241.1 - 1.1e-11 44.8 0.0 2.7e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EKX36241.1 - 2.8e-06 27.4 0.0 4.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4813 PF16072.5 EKX36241.1 - 0.16 11.6 0.0 0.24 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) AAA_22 PF13401.6 EKX36241.1 - 0.19 12.0 0.2 1.2 9.4 0.2 2.4 1 1 0 1 1 1 0 AAA domain Beta_helix PF13229.6 EKX36242.1 - 0.0025 17.7 0.0 0.0079 16.1 0.0 1.8 2 0 0 2 2 2 1 Right handed beta helix region DUF4457 PF14652.6 EKX36243.1 - 2.3e-129 431.4 0.0 6.1e-76 255.8 0.0 2.9 2 1 1 3 3 3 3 Domain of unknown function (DUF4457) Sad1_UNC PF07738.13 EKX36243.1 - 0.013 15.5 0.0 0.49 10.4 0.0 3.3 4 0 0 4 4 4 0 Sad1 / UNC-like C-terminal TPR_2 PF07719.17 EKX36244.1 - 0.0016 18.4 0.2 0.0043 17.1 0.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX36244.1 - 0.0031 17.3 0.6 0.006 16.4 0.6 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX36244.1 - 0.0036 16.9 0.0 0.0057 16.3 0.0 1.3 1 0 0 1 1 1 1 TPR repeat Glu_cyclase_2 PF05096.12 EKX36245.1 - 2.1e-69 233.7 0.2 1.3e-63 214.8 0.0 2.1 2 0 0 2 2 2 2 Glutamine cyclotransferase Tox-ODYAM1 PF15642.6 EKX36245.1 - 0.011 14.7 0.0 0.017 14.1 0.0 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus FCSD-flav_bind PF09242.11 EKX36247.1 - 0.0088 16.4 0.0 0.03 14.7 0.0 1.9 2 0 0 2 2 2 1 Flavocytochrome c sulphide dehydrogenase, flavin-binding DUF2868 PF11067.8 EKX36248.1 - 0.0016 18.0 2.5 0.002 17.7 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2868) Trypan_PARP PF05887.11 EKX36248.1 - 0.051 13.6 6.5 0.068 13.1 6.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CotJB PF12652.7 EKX36249.1 - 0.17 12.2 1.4 0.81 10.0 0.0 2.8 3 0 0 3 3 3 0 CotJB protein D5_N PF08706.11 EKX36251.1 - 2.8e-14 53.6 1.0 2.8e-14 53.6 1.0 2.0 2 0 0 2 2 2 1 D5 N terminal like PIP5K PF01504.18 EKX36253.1 - 7.7e-68 228.7 0.0 9.1e-68 228.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Ins145_P3_rec PF08709.11 EKX36254.1 - 1.8e-08 33.8 0.0 3.6e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor CCDC154 PF15450.6 EKX36254.1 - 5.1e-05 22.0 5.9 5.1e-05 22.0 5.9 1.8 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 154 SAS4 PF15460.6 EKX36254.1 - 0.62 10.2 6.1 1.2 9.2 1.4 2.6 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 TPR_MLP1_2 PF07926.12 EKX36254.1 - 4.9 7.2 16.8 0.23 11.5 0.8 3.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4164 PF13747.6 EKX36254.1 - 8.1 6.8 9.6 9.2 6.6 4.4 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Rft-1 PF04506.13 EKX36255.1 - 0.11 11.2 0.1 0.14 10.8 0.1 1.1 1 0 0 1 1 1 0 Rft protein Cas1_AcylT PF07779.12 EKX36256.1 - 1e-82 278.6 26.7 1.2e-82 278.3 26.7 1.0 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p LRR_6 PF13516.6 EKX36257.1 - 3.7e-23 79.6 29.6 0.00013 21.8 0.3 9.3 9 0 0 9 9 9 6 Leucine Rich repeat LRR_4 PF12799.7 EKX36257.1 - 3.8e-06 27.1 18.1 0.016 15.6 0.0 5.7 2 2 4 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX36257.1 - 4.8e-05 23.3 15.3 8.5 7.4 0.0 7.8 7 1 0 7 7 7 3 Leucine Rich Repeat LRR_8 PF13855.6 EKX36257.1 - 0.00056 19.6 25.6 0.0064 16.2 0.2 5.9 5 3 0 5 5 5 3 Leucine rich repeat 2OG-FeII_Oxy_3 PF13640.6 EKX36258.1 - 0.0003 21.6 0.0 0.00052 20.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Biotin_lipoyl_2 PF13533.6 EKX36258.1 - 0.081 12.8 0.0 0.26 11.2 0.0 1.9 1 0 0 1 1 1 0 Biotin-lipoyl like IMCp PF12314.8 EKX36259.1 - 9.7e-21 73.9 227.4 7.7e-05 22.9 18.6 13.7 3 3 10 14 14 14 13 Inner membrane complex protein VPR PF00522.18 EKX36259.1 - 0.0044 17.0 0.3 4e+02 1.1 0.0 5.8 6 0 0 6 6 6 0 VPR/VPX protein Ephrin_rec_like PF07699.13 EKX36259.1 - 0.13 12.0 14.5 0.041 13.7 2.2 2.5 1 1 1 2 2 2 0 Putative ephrin-receptor like PA14 PF07691.12 EKX36260.1 - 3.3e-10 39.9 0.0 1.7e-07 31.1 0.0 2.6 3 0 0 3 3 3 2 PA14 domain PA PF02225.22 EKX36260.1 - 1.2e-05 25.2 0.0 2.5e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 PA domain GLEYA PF10528.9 EKX36260.1 - 0.066 13.6 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 GLEYA domain Ank_2 PF12796.7 EKX36261.1 - 1.7e-06 28.5 0.2 0.0068 17.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) PARP PF00644.20 EKX36261.1 - 1.8e-05 24.4 0.1 4.6e-05 23.1 0.1 1.7 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Ank_5 PF13857.6 EKX36261.1 - 0.00031 21.0 1.5 0.15 12.4 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX36261.1 - 0.0012 19.3 2.1 0.025 15.1 0.5 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX36261.1 - 0.043 14.4 0.2 5.4 7.9 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat UvsY PF11056.8 EKX36261.1 - 0.059 13.7 0.2 0.21 11.9 0.2 1.8 1 1 1 2 2 2 0 Recombination, repair and ssDNA binding protein UvsY UPF0154 PF03672.13 EKX36261.1 - 0.13 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) GDP_Man_Dehyd PF16363.5 EKX36264.1 - 1.8e-60 205.1 0.0 3.9e-60 204.0 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EKX36264.1 - 1.5e-50 171.9 0.0 2e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EKX36264.1 - 4.3e-13 48.9 0.0 6.1e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EKX36264.1 - 4e-11 42.6 0.0 1.6e-06 27.5 0.0 2.4 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 EKX36264.1 - 2.7e-10 39.8 0.0 5.5e-10 38.8 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EKX36264.1 - 3.8e-09 36.1 0.1 1e-05 24.9 0.0 2.6 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein adh_short PF00106.25 EKX36264.1 - 0.0042 16.6 0.0 0.0093 15.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 EKX36264.1 - 0.008 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EKX36264.1 - 0.15 12.0 0.0 0.46 10.4 0.0 1.8 2 0 0 2 2 2 0 KR domain TP6A_N PF04406.14 EKX36265.1 - 2.8e-17 62.4 0.0 1e-15 57.4 0.0 2.4 2 0 0 2 2 2 2 Type IIB DNA topoisomerase HSP70 PF00012.20 EKX36266.1 - 1.6e-266 885.3 9.2 1.8e-266 885.1 9.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EKX36266.1 - 1.5e-14 53.6 3.7 2.7e-13 49.5 0.2 2.8 3 0 0 3 3 3 2 MreB/Mbl protein Phasin PF05597.11 EKX36266.1 - 0.0054 16.7 3.5 0.013 15.5 3.5 1.6 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) CDH1_2_SANT_HL1 PF18375.1 EKX36266.1 - 0.048 14.3 1.2 0.048 14.3 1.2 2.2 3 0 0 3 3 3 0 CDH1/2 SANT-Helical linker 1 DUF1542 PF07564.11 EKX36266.1 - 0.091 12.9 5.9 0.098 12.8 3.0 2.4 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1542) CARD PF00619.21 EKX36266.1 - 0.12 12.4 1.2 0.36 10.9 0.1 2.3 3 0 0 3 3 3 0 Caspase recruitment domain Emaravirus_P4 PF16505.5 EKX36266.1 - 0.14 11.2 1.7 0.25 10.3 1.7 1.3 1 0 0 1 1 1 0 P4 movement protein of Emaravirus, and the 30K superfamily XH PF03469.14 EKX36266.1 - 0.19 11.7 0.9 0.66 9.9 0.5 2.2 2 0 0 2 2 2 0 XH domain RRF PF01765.19 EKX36266.1 - 0.25 11.3 4.5 0.59 10.1 4.5 1.6 1 0 0 1 1 1 0 Ribosome recycling factor TBCA PF02970.16 EKX36266.1 - 1.5 9.2 6.4 4.7 7.6 5.4 2.3 1 1 1 2 2 2 0 Tubulin binding cofactor A Mito_carr PF00153.27 EKX36267.1 - 2.5e-41 139.5 8.1 1.7e-15 56.7 0.2 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein TPR_12 PF13424.6 EKX36268.1 - 8.7e-11 42.0 8.2 8.5e-05 22.8 0.6 4.7 3 2 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX36268.1 - 1.8e-07 30.7 6.5 0.00037 20.2 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX36268.1 - 6.1e-07 29.1 2.9 3.3 8.0 0.1 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX36268.1 - 6.2e-05 22.7 0.4 2.6 8.0 0.0 5.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TssD PF17642.1 EKX36268.1 - 0.01 15.6 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 Hemolysin coregulated protein Hcp (TssD) TPR_7 PF13176.6 EKX36268.1 - 0.046 13.7 4.4 64 3.9 0.2 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX36268.1 - 0.18 12.1 5.7 37 4.9 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.7 EKX36268.1 - 0.19 11.8 2.0 1.5 8.9 0.5 2.6 2 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_6 PF13174.6 EKX36268.1 - 0.22 12.2 3.1 24 5.9 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_L2_C PF03947.18 EKX36269.1 - 4.4e-51 172.3 2.3 4.4e-51 172.3 2.3 2.0 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EKX36269.1 - 2.1e-24 85.3 0.2 6e-23 80.6 0.1 2.9 3 0 0 3 3 3 1 Ribosomal Proteins L2, RNA binding domain RETICULATA-like PF11891.8 EKX36270.1 - 1.7e-18 67.1 0.9 4.8e-17 62.4 0.0 2.1 2 0 0 2 2 2 1 Protein RETICULATA-related CENP-B_dimeris PF09026.10 EKX36270.1 - 0.0035 17.7 19.2 0.0035 17.7 19.2 1.9 2 0 0 2 2 2 1 Centromere protein B dimerisation domain FAM176 PF14851.6 EKX36270.1 - 0.012 15.2 0.1 0.024 14.3 0.1 1.5 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.13 EKX36270.1 - 0.018 14.9 2.7 0.03 14.2 2.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region RNA_pol_3_Rpc31 PF11705.8 EKX36270.1 - 0.02 15.1 10.2 0.033 14.5 10.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PPP4R2 PF09184.11 EKX36270.1 - 0.036 13.7 3.0 0.047 13.3 3.0 1.1 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 EKX36270.1 - 0.2 10.9 20.6 0.31 10.3 20.6 1.2 1 0 0 1 1 1 0 NOA36 protein TFB6 PF17110.5 EKX36270.1 - 0.32 10.7 1.8 0.56 9.9 1.8 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH RXT2_N PF08595.11 EKX36270.1 - 0.5 10.4 7.4 0.82 9.7 7.4 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal GCIP PF13324.6 EKX36270.1 - 0.73 9.4 9.3 2.1 7.9 8.7 1.9 2 1 0 2 2 2 0 Grap2 and cyclin-D-interacting DUF2457 PF10446.9 EKX36270.1 - 1.9 7.5 26.1 2.6 7.1 26.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) WRNPLPNID PF15017.6 EKX36270.1 - 2 9.3 10.2 0.094 13.6 4.3 1.8 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box SDA1 PF05285.12 EKX36270.1 - 7.7 5.8 11.9 11 5.3 11.9 1.1 1 0 0 1 1 1 0 SDA1 Pkinase_Tyr PF07714.17 EKX36272.1 - 0.0045 16.3 0.3 0.19 11.0 0.2 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Dpy-30 PF05186.13 EKX36272.1 - 0.27 11.0 0.7 7.3 6.4 0.0 2.7 3 0 0 3 3 3 0 Dpy-30 motif LysM PF01476.20 EKX36273.1 - 7.1e-06 26.0 0.2 0.0093 16.0 0.1 2.8 2 0 0 2 2 2 2 LysM domain OTU PF02338.19 EKX36275.1 - 3.4e-13 50.2 0.0 8.3e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EKX36275.1 - 0.0014 18.1 0.9 0.027 13.9 0.0 2.3 2 0 0 2 2 2 1 Peptidase C65 Otubain TFIIA PF03153.13 EKX36275.1 - 0.18 11.8 14.5 0.21 11.6 14.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CPBP PF02517.16 EKX36276.1 - 2e-20 72.9 1.7 2e-20 72.9 1.7 1.8 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease MatE PF01554.18 EKX36277.1 - 5.7e-14 52.1 22.7 1.3e-10 41.2 1.3 3.1 2 1 1 3 3 3 2 MatE Polysacc_synt_C PF14667.6 EKX36277.1 - 3.8e-07 30.2 0.3 3.8e-07 30.2 0.3 3.9 2 1 2 4 4 4 1 Polysaccharide biosynthesis C-terminal domain DUF1385 PF07136.11 EKX36277.1 - 0.066 12.5 0.4 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1385) Cytochrom_B_N_2 PF13631.6 EKX36277.1 - 0.35 10.9 4.3 0.17 11.9 1.4 2.0 3 0 0 3 3 3 0 Cytochrome b(N-terminal)/b6/petB DUF2613 PF11021.8 EKX36277.1 - 2.3 8.4 5.8 8.1 6.6 1.7 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) DUF2207 PF09972.9 EKX36277.1 - 2.3 6.9 3.0 1.9 7.1 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Kinesin PF00225.23 EKX36278.1 - 6e-97 324.6 0.0 7.2e-97 324.3 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX36278.1 - 1.9e-20 73.3 0.0 4.7e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding PRKG1_interact PF15898.5 EKX36278.1 - 0.022 15.7 0.2 0.096 13.6 0.0 2.1 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Shugoshin_N PF07558.11 EKX36278.1 - 0.036 13.9 0.7 0.088 12.7 0.7 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Yae1_N PF09811.9 EKX36278.1 - 1.3 8.7 9.3 1.3 8.7 2.1 2.6 2 0 0 2 2 2 0 Essential protein Yae1, N terminal Mak10 PF04112.13 EKX36279.1 - 9.5e-30 103.3 0.2 6e-20 71.4 0.0 2.5 1 1 1 2 2 2 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase WD40 PF00400.32 EKX36280.1 - 5.3e-51 169.5 26.8 3.1e-10 40.5 1.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX36280.1 - 4.3e-30 103.9 9.0 2.2e-07 31.1 0.1 5.2 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX36280.1 - 5.7e-10 38.7 2.3 0.01 14.8 0.0 5.2 1 1 5 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 EKX36280.1 - 3.2e-07 30.0 11.8 0.11 11.8 0.0 5.5 1 1 5 6 6 6 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 EKX36280.1 - 2.2e-06 27.4 0.2 14 5.7 0.0 5.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 EKX36280.1 - 4.2e-05 22.4 6.0 0.027 13.1 0.0 3.9 1 1 3 4 4 4 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 EKX36280.1 - 5.5e-05 23.2 0.1 0.041 13.9 0.0 4.1 2 1 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 EKX36280.1 - 0.0016 17.8 0.0 22 4.2 0.0 3.9 1 1 2 4 4 4 0 WD40-like domain IKI3 PF04762.12 EKX36280.1 - 0.0024 16.0 8.5 0.16 10.0 0.2 3.9 1 1 2 3 3 3 3 IKI3 family Ribosomal_L21e PF01157.18 EKX36280.1 - 0.004 17.0 0.0 0.87 9.5 0.0 2.5 2 0 0 2 2 2 1 Ribosomal protein L21e Methyltransf_3 PF01596.17 EKX36280.1 - 0.004 16.4 0.0 0.44 9.7 0.0 2.3 2 0 0 2 2 2 1 O-methyltransferase Coatomer_WDAD PF04053.14 EKX36280.1 - 0.0084 15.2 0.8 0.27 10.2 0.3 2.4 1 1 1 2 2 2 1 Coatomer WD associated region HPS3_N PF14761.6 EKX36280.1 - 0.023 14.2 0.0 3.2 7.2 0.0 3.1 1 1 2 4 4 4 0 Hermansky-Pudlak syndrome 3 CHAP PF05257.16 EKX36280.1 - 0.055 14.0 5.4 7.8 7.2 0.1 3.1 2 1 0 2 2 2 0 CHAP domain DUF5122 PF17164.4 EKX36280.1 - 0.12 12.7 3.7 1.3 9.4 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller TFIIIC_delta PF12657.7 EKX36280.1 - 9.3 6.1 11.3 21 5.0 0.3 4.4 3 1 0 4 4 4 0 Transcription factor IIIC subunit delta N-term Pkinase_Tyr PF07714.17 EKX36281.1 - 1.1e-25 90.4 0.0 1.3e-25 90.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX36281.1 - 2.3e-23 82.9 0.0 2.7e-23 82.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Vint PF14623.6 EKX36281.1 - 0.0046 16.8 0.0 0.0068 16.2 0.0 1.2 1 0 0 1 1 1 1 Hint-domain Kdo PF06293.14 EKX36281.1 - 0.022 14.1 0.1 0.031 13.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EKX36281.1 - 0.047 13.0 0.0 0.085 12.2 0.0 1.7 1 1 0 1 1 1 0 Kinase-like IQ PF00612.27 EKX36282.1 - 2.7e-12 45.3 14.0 0.012 15.3 0.0 4.8 4 0 0 4 4 4 4 IQ calmodulin-binding motif Carn_acyltransf PF00755.20 EKX36283.1 - 5.5e-176 586.7 0.0 6.3e-176 586.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase TNFR_c6 PF00020.18 EKX36284.1 - 1.4e-07 31.7 29.3 1.5e-06 28.5 12.8 3.0 1 1 2 3 3 3 3 TNFR/NGFR cysteine-rich region EGF_2 PF07974.13 EKX36285.1 - 1.1e-09 38.4 71.7 0.0012 19.2 17.0 4.2 3 2 2 5 5 5 3 EGF-like domain EGF PF00008.27 EKX36285.1 - 2e-07 31.2 48.4 0.02 15.2 11.0 3.8 3 1 0 3 3 3 3 EGF-like domain DSL PF01414.19 EKX36285.1 - 9.6e-06 25.8 58.1 0.0015 18.8 15.9 3.1 3 0 0 3 3 3 2 Delta serrate ligand Laminin_EGF PF00053.24 EKX36285.1 - 7.1e-05 22.9 52.9 0.51 10.5 13.5 4.3 1 1 3 4 4 4 3 Laminin EGF domain BolA PF01722.18 EKX36286.1 - 9.9e-30 102.7 1.1 1.3e-29 102.2 1.1 1.2 1 0 0 1 1 1 1 BolA-like protein DUF2475 PF10629.9 EKX36287.1 - 6.3e-05 23.1 3.4 0.00011 22.3 0.1 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2475) Rhodanese PF00581.20 EKX36289.1 - 3.5e-26 91.8 0.0 3.4e-18 66.1 0.0 3.0 2 1 0 2 2 2 2 Rhodanese-like domain ADH_N_assoc PF13823.6 EKX36289.1 - 0.16 11.9 0.0 0.4 10.7 0.0 1.7 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated Malate_synthase PF01274.22 EKX36291.1 - 1.2e-141 472.6 0.0 1.6e-141 472.2 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Dus PF01207.17 EKX36292.1 - 1.3e-51 175.6 0.0 1.6e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) CBM_4_9 PF02018.17 EKX36293.1 - 0.0079 16.5 0.3 0.017 15.4 0.1 1.7 2 0 0 2 2 2 1 Carbohydrate binding domain DUF4082 PF13313.6 EKX36293.1 - 0.025 14.6 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4082) Ank_5 PF13857.6 EKX36294.1 - 2.2e-08 34.2 2.8 0.0032 17.7 0.1 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX36294.1 - 0.0001 22.5 0.3 0.15 12.7 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat DUF4258 PF14076.6 EKX36294.1 - 0.00017 21.9 0.0 0.0017 18.7 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4258) Ank_2 PF12796.7 EKX36294.1 - 0.00031 21.3 0.0 0.075 13.6 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX36294.1 - 0.001 19.6 0.2 0.029 15.0 0.0 3.3 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX36294.1 - 0.043 14.3 0.0 0.27 11.7 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat ALF PF03752.13 EKX36294.1 - 0.052 13.5 0.1 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 Short repeats of unknown function PARP PF00644.20 EKX36295.1 - 9.9e-23 80.8 0.2 5.1e-21 75.2 0.2 2.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Exotox-A_cataly PF09009.10 EKX36295.1 - 3.9e-05 23.5 0.0 4.4e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Exotoxin A catalytic CDC37_N PF03234.14 EKX36296.1 - 4.8e-08 34.0 9.7 4.8e-08 34.0 9.7 2.2 2 1 0 2 2 2 1 Cdc37 N terminal kinase binding TPR_1 PF00515.28 EKX36296.1 - 6.9e-07 28.8 20.1 5.2e-05 22.9 0.4 4.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX36296.1 - 5.2e-06 26.2 9.4 0.00028 20.8 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX36296.1 - 0.0014 18.7 6.9 0.15 12.4 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat MAS20 PF02064.15 EKX36296.1 - 0.073 13.2 3.9 0.15 12.1 3.9 1.5 1 0 0 1 1 1 0 MAS20 protein import receptor TPR_11 PF13414.6 EKX36296.1 - 0.081 12.6 10.3 0.1 12.3 0.0 3.6 4 0 0 4 4 4 0 TPR repeat TPR_14 PF13428.6 EKX36296.1 - 0.14 13.1 0.1 23 6.1 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX36296.1 - 1.5 9.2 4.8 1 9.7 0.1 3.1 4 2 0 4 4 4 0 Tetratricopeptide repeat Mak16 PF04874.14 EKX36297.1 - 0.02 15.5 4.3 0.041 14.5 4.3 1.5 1 0 0 1 1 1 0 Mak16 protein C-terminal region Ufd2P_core PF10408.9 EKX36297.1 - 0.061 11.9 1.1 0.096 11.3 1.1 1.3 1 0 0 1 1 1 0 Ubiquitin elongating factor core DUF4611 PF15387.6 EKX36297.1 - 0.12 12.6 3.3 0.28 11.4 3.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) HSP20 PF00011.21 EKX36298.1 - 8.7e-14 51.5 0.1 1.3e-13 50.9 0.1 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EKX36298.1 - 7.7e-05 22.2 0.0 0.00024 20.6 0.0 1.9 1 1 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 EKX36299.1 - 1.4e-11 44.5 0.0 2.3e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EKX36299.1 - 0.0011 18.5 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 HSP20-like domain found in ArsA SPX PF03105.19 EKX36299.1 - 0.035 14.0 3.3 0.042 13.8 3.3 1.1 1 0 0 1 1 1 0 SPX domain ANAPC15 PF15243.6 EKX36299.1 - 0.29 11.6 3.7 0.31 11.5 0.4 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 15 DUF4407 PF14362.6 EKX36299.1 - 0.43 9.9 4.1 0.59 9.4 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 EKX36299.1 - 0.92 10.0 7.0 1.4 9.4 7.0 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region HSP20 PF00011.21 EKX36301.1 - 0.00032 20.8 0.0 0.00066 19.8 0.0 1.5 1 0 0 1 1 1 1 Hsp20/alpha crystallin family HCMV_UL139 PF12507.8 EKX36301.1 - 0.06 13.7 0.3 0.093 13.1 0.3 1.2 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein OEP PF02321.18 EKX36301.1 - 0.29 10.9 8.4 0.62 9.8 6.8 2.0 2 0 0 2 2 2 0 Outer membrane efflux protein Alanine_zipper PF11839.8 EKX36301.1 - 0.32 11.4 14.3 0.69 10.3 14.3 1.5 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein HSP20 PF00011.21 EKX36302.1 - 2.2e-11 43.8 0.0 4.1e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EKX36302.1 - 0.00058 19.4 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 HSP20-like domain found in ArsA ANAPC15 PF15243.6 EKX36302.1 - 0.037 14.4 3.6 0.082 13.3 0.5 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 15 DUF4407 PF14362.6 EKX36302.1 - 0.42 9.9 4.4 0.54 9.6 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 EKX36302.1 - 1.4 9.5 8.9 1.8 9.1 8.9 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region FUSC PF04632.12 EKX36302.1 - 5.1 5.5 11.0 6.3 5.2 11.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family UPF0564 PF10595.9 EKX36303.1 - 0.00012 21.3 15.6 0.00012 21.3 15.6 4.3 4 2 2 6 6 6 1 Uncharacterised protein family UPF0564 UPF0564 PF10595.9 EKX36304.1 - 2e-14 53.4 26.6 2e-14 53.4 26.6 2.4 1 1 0 2 2 2 1 Uncharacterised protein family UPF0564 MgsA_C PF12002.8 EKX36304.1 - 0.16 11.9 2.4 0.19 11.7 1.3 1.7 1 1 0 1 1 1 0 MgsA AAA+ ATPase C terminal YtxH PF12732.7 EKX36304.1 - 1.3 9.6 8.3 0.076 13.5 2.2 2.1 2 0 0 2 2 2 0 YtxH-like protein OAD_gamma PF04277.13 EKX36304.1 - 5.3 7.7 6.8 6.1 7.5 0.0 3.1 2 1 1 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF2428 PF10350.9 EKX36304.1 - 9.1 5.4 9.5 20 4.3 9.3 1.7 1 1 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) C2 PF00168.30 EKX36305.1 - 8.9e-25 87.0 0.0 2.3e-13 50.3 0.0 2.7 2 0 0 2 2 2 2 C2 domain PB1 PF00564.24 EKX36305.1 - 0.0025 17.7 0.2 2.6 8.0 0.0 2.9 3 0 0 3 3 3 2 PB1 domain Ank_2 PF12796.7 EKX36305.1 - 0.0047 17.5 0.0 0.82 10.3 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX36305.1 - 0.0073 16.9 0.0 0.36 11.5 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX36305.1 - 0.021 15.2 0.0 26 5.5 0.0 3.7 3 0 0 3 3 3 0 Ankyrin repeat Ank_3 PF13606.6 EKX36305.1 - 0.057 14.0 0.0 22 6.0 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat zf-ribbon_3 PF13248.6 EKX36306.1 - 0.0045 16.3 0.3 0.01 15.2 0.3 1.6 1 0 0 1 1 1 1 zinc-ribbon domain Ank_4 PF13637.6 EKX36307.1 - 2.3e-09 37.6 0.0 1e-05 25.9 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX36307.1 - 4.3e-07 30.4 0.0 2.4e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX36307.1 - 0.00015 22.1 0.0 0.029 14.8 0.1 2.9 2 1 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EKX36307.1 - 0.0014 18.9 0.2 0.17 12.3 0.1 3.2 2 1 0 2 2 2 1 Ankyrin repeats (many copies) CM_2 PF01817.21 EKX36307.1 - 0.0075 16.6 1.5 0.0093 16.3 0.3 1.7 2 0 0 2 2 2 1 Chorismate mutase type II Ank_3 PF13606.6 EKX36307.1 - 0.033 14.7 0.0 1.4 9.8 0.0 3.4 4 0 0 4 4 4 0 Ankyrin repeat VCH_CASS14 PF18315.1 EKX36307.1 - 0.037 14.1 0.0 0.2 11.7 0.0 2.1 1 1 1 2 2 2 0 Integron cassette protein VCH_CASS1 chain Dynamin_N PF00350.23 EKX36308.1 - 8.3e-31 107.3 0.1 1.2e-30 106.8 0.1 1.2 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EKX36308.1 - 8.2e-16 58.1 0.0 1.3e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 EKX36308.1 - 8.1e-06 25.9 0.1 5.4e-05 23.2 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EKX36308.1 - 0.0069 16.9 0.0 0.014 15.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 EKX36308.1 - 0.015 15.1 0.2 0.033 13.9 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 EKX36308.1 - 0.042 14.1 0.0 5.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Tim54 PF11711.8 EKX36309.1 - 0.089 11.6 19.0 0.11 11.3 19.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RP-C_C PF11800.8 EKX36309.1 - 0.12 12.5 15.4 0.13 12.3 15.4 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF4614 PF15391.6 EKX36309.1 - 0.18 11.8 14.0 0.21 11.6 14.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Vfa1 PF08432.10 EKX36309.1 - 0.2 12.0 26.0 0.23 11.8 26.0 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDRGK PF09756.9 EKX36309.1 - 0.39 10.3 36.0 0.52 9.9 36.0 1.2 1 0 0 1 1 1 0 DDRGK domain Gti1_Pac2 PF09729.9 EKX36309.1 - 0.4 10.7 14.8 0.43 10.6 14.8 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Nop14 PF04147.12 EKX36309.1 - 0.5 8.5 34.0 0.56 8.4 34.0 1.0 1 0 0 1 1 1 0 Nop14-like family SLC12 PF03522.15 EKX36309.1 - 1.1 8.2 18.3 1.1 8.2 18.3 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Rtf2 PF04641.12 EKX36309.1 - 1.3 8.3 21.6 1.4 8.2 21.6 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Lin-8 PF03353.15 EKX36309.1 - 1.3 8.5 22.9 1.4 8.4 22.9 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RR_TM4-6 PF06459.12 EKX36309.1 - 1.5 8.6 29.2 1.7 8.4 29.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4045 PF13254.6 EKX36309.1 - 1.7 8.2 19.4 1.7 8.2 19.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF2151 PF10221.9 EKX36309.1 - 1.7 7.1 18.5 1.9 7.0 18.5 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator DUF2126 PF09899.9 EKX36309.1 - 1.7 6.6 9.3 1.8 6.6 9.3 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) MDM1 PF15501.6 EKX36309.1 - 1.8 7.6 26.3 1.9 7.6 26.3 1.0 1 0 0 1 1 1 0 Nuclear protein MDM1 CDC45 PF02724.14 EKX36309.1 - 1.9 6.7 30.1 2.2 6.5 30.1 1.0 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.13 EKX36309.1 - 2.2 6.9 22.4 2.5 6.8 22.4 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2052 PF09747.9 EKX36309.1 - 2.3 8.3 32.3 2.9 8.0 32.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) BUD22 PF09073.10 EKX36309.1 - 2.3 7.5 32.4 2.5 7.3 32.4 1.0 1 0 0 1 1 1 0 BUD22 PPL5 PF18168.1 EKX36309.1 - 2.4 7.4 15.4 2.9 7.1 15.4 1.2 1 0 0 1 1 1 0 Prim-pol family 5 GAGA_bind PF06217.12 EKX36309.1 - 2.6 8.2 14.5 3 8.0 14.5 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Endostatin PF06482.11 EKX36309.1 - 2.9 7.3 10.7 3.1 7.2 10.7 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Merozoite_SPAM PF07133.11 EKX36309.1 - 3 7.8 48.2 3.7 7.5 48.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Spore_coat_CotO PF14153.6 EKX36309.1 - 3.1 7.7 31.0 3.9 7.4 31.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO ALMT PF11744.8 EKX36309.1 - 3.1 6.5 15.0 3.5 6.4 15.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter SDA1 PF05285.12 EKX36309.1 - 3.2 7.1 37.7 3.6 6.9 37.7 1.1 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 EKX36309.1 - 3.2 6.4 25.7 3.6 6.2 25.7 1.0 1 0 0 1 1 1 0 Presenilin Membralin PF09746.9 EKX36309.1 - 3.9 6.4 11.1 4.3 6.3 11.1 1.0 1 0 0 1 1 1 0 Tumour-associated protein FGF-BP1 PF06473.12 EKX36309.1 - 4 7.2 21.4 4.8 7.0 21.4 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Raftlin PF15250.6 EKX36309.1 - 4.3 6.0 18.1 4.5 5.9 18.1 1.0 1 0 0 1 1 1 0 Raftlin CCSAP PF15748.5 EKX36309.1 - 4.7 7.3 25.0 5.5 7.1 25.0 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated FAM60A PF15396.6 EKX36309.1 - 5 7.1 16.5 5.6 6.9 16.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A LAP1C PF05609.12 EKX36309.1 - 5.7 5.9 21.0 6 5.8 21.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) MDM10 PF12519.8 EKX36309.1 - 6.5 5.5 17.0 6.8 5.4 17.0 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Paf1 PF03985.13 EKX36309.1 - 6.6 5.6 38.4 8 5.3 38.4 1.2 1 0 0 1 1 1 0 Paf1 SpoIIIAH PF12685.7 EKX36309.1 - 7.3 6.4 25.4 8.8 6.1 25.4 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Ureide_permease PF07168.11 EKX36309.1 - 7.3 5.2 10.2 9.5 4.9 10.2 1.3 1 0 0 1 1 1 0 Ureide permease Bud13 PF09736.9 EKX36309.1 - 7.4 7.0 27.7 10 6.5 27.7 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Neur_chan_memb PF02932.16 EKX36309.1 - 7.7 6.5 13.1 8.4 6.4 13.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MCM_bind PF09739.9 EKX36309.1 - 7.8 4.8 19.8 8.4 4.7 19.8 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor SID-1_RNA_chan PF13965.6 EKX36309.1 - 8.2 4.7 12.3 9 4.6 12.3 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 MMR1 PF08505.10 EKX36309.1 - 9.2 6.5 19.7 11 6.3 19.7 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein BORG_CEP PF14957.6 EKX36309.1 - 10 7.3 15.0 13 7.0 15.0 1.2 1 0 0 1 1 1 0 Cdc42 effector Kelch_1 PF01344.25 EKX36310.1 - 1.4e-34 117.4 0.2 4.2e-08 32.7 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 EKX36310.1 - 2.4e-18 65.7 2.2 0.0061 16.8 0.0 6.2 5 1 1 6 6 6 4 Kelch motif Kelch_4 PF13418.6 EKX36310.1 - 4.8e-13 48.9 0.6 0.018 15.0 0.0 6.2 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 EKX36310.1 - 1.6e-11 43.7 6.4 0.016 15.1 0.0 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 EKX36310.1 - 3.5e-08 33.3 0.6 5.6 7.1 0.0 5.4 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.6 EKX36310.1 - 1.5e-06 28.3 0.3 2.1 8.7 0.0 5.0 5 0 0 5 5 5 2 Galactose oxidase, central domain DDHD PF02862.17 EKX36310.1 - 0.033 14.3 5.9 0.044 14.0 5.9 1.2 1 0 0 1 1 1 0 DDHD domain BNR_3 PF13859.6 EKX36310.1 - 0.049 12.9 6.1 0.06 12.6 4.8 1.7 2 0 0 2 2 2 0 BNR repeat-like domain Membralin PF09746.9 EKX36310.1 - 0.26 10.3 4.7 0.33 10.0 4.7 1.1 1 0 0 1 1 1 0 Tumour-associated protein Suf PF05843.14 EKX36310.1 - 0.34 10.8 7.9 0.51 10.3 7.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Otopetrin PF03189.13 EKX36310.1 - 0.36 9.6 1.5 0.4 9.4 1.5 1.1 1 0 0 1 1 1 0 Otopetrin DUF5308 PF17233.2 EKX36310.1 - 0.46 10.7 6.3 0.68 10.1 6.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Trypan_PARP PF05887.11 EKX36310.1 - 0.71 9.9 22.1 3.1 7.8 20.9 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Zip PF02535.22 EKX36310.1 - 0.77 8.9 7.7 0.9 8.7 7.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SpoIIP PF07454.11 EKX36310.1 - 1.7 8.0 19.3 2.3 7.6 19.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Vfa1 PF08432.10 EKX36310.1 - 2.6 8.4 20.6 4 7.7 20.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2201_N PF13203.6 EKX36310.1 - 4.8 6.7 12.8 7.4 6.1 12.8 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain TERB2 PF15101.6 EKX36310.1 - 5.8 6.9 18.0 8.4 6.4 18.0 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SDA1 PF05285.12 EKX36310.1 - 7.2 5.9 28.1 9.7 5.5 28.1 1.2 1 0 0 1 1 1 0 SDA1 Eapp_C PF10238.9 EKX36310.1 - 7.7 6.6 14.8 14 5.7 14.8 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein Ndc1_Nup PF09531.10 EKX36310.1 - 7.8 5.0 4.8 9.4 4.8 4.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup XAP5 PF04921.14 EKX36310.1 - 9.2 6.0 16.7 13 5.5 16.7 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator RP-C_C PF11800.8 EKX36310.1 - 9.5 6.3 17.2 14 5.7 17.2 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region LMF1 PF06762.14 EKX36311.1 - 8.3e-95 318.5 6.6 1.1e-94 318.1 6.6 1.2 1 0 0 1 1 1 1 Lipase maturation factor G-patch PF01585.23 EKX36312.1 - 3.7e-09 36.3 2.4 8.8e-09 35.1 2.4 1.7 1 1 0 1 1 1 1 G-patch domain R3H PF01424.22 EKX36312.1 - 7.4e-09 35.5 0.0 2.3e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 R3H domain MID_MedPIWI PF18296.1 EKX36312.1 - 0.025 14.4 2.6 0.04 13.7 2.6 1.2 1 0 0 1 1 1 0 MID domain of medPIWI cwf18 PF08315.12 EKX36312.1 - 1.3 9.7 16.6 0.098 13.3 10.8 1.9 2 0 0 2 2 2 0 cwf18 pre-mRNA splicing factor FAM60A PF15396.6 EKX36312.1 - 1.6 8.7 9.2 1.7 8.6 3.3 2.1 2 0 0 2 2 2 0 Protein Family FAM60A PAC1 PF16094.5 EKX36312.1 - 7.9 5.6 13.1 14 4.8 13.1 1.3 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 AAA_11 PF13086.6 EKX36312.1 - 8.4 6.1 8.9 3.3 7.4 4.5 2.0 2 0 0 2 2 2 0 AAA domain Glyco_transf_20 PF00982.21 EKX36313.1 - 5e-100 335.4 0.0 6.8e-100 335.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EKX36313.1 - 1.6e-30 106.0 0.0 5e-30 104.4 0.0 1.7 2 0 0 2 2 2 1 Trehalose-phosphatase CBM_20 PF00686.19 EKX36313.1 - 3.2e-24 84.7 0.2 7.7e-24 83.4 0.2 1.6 1 0 0 1 1 1 1 Starch binding domain RRM_1 PF00076.22 EKX36314.1 - 2.8e-07 30.2 0.0 6.6e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SATase_N PF06426.14 EKX36315.1 - 3.2e-19 69.2 0.1 5.9e-19 68.4 0.1 1.4 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 EKX36315.1 - 2.8e-08 33.2 9.5 0.00031 20.3 3.1 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EKX36315.1 - 2.5e-05 23.9 10.1 0.00081 19.1 3.3 2.5 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase DUF1139 PF06599.11 EKX36315.1 - 0.14 11.5 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1139) adh_short PF00106.25 EKX36316.1 - 2e-13 50.2 0.2 3.1e-13 49.6 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EKX36316.1 - 2.3e-07 30.9 0.1 3.5e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF2967 PF11179.8 EKX36316.1 - 0.01 14.0 11.7 0.014 13.5 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Eno-Rase_NADH_b PF12242.8 EKX36316.1 - 2.7 7.8 5.7 0.61 9.9 0.3 2.7 3 2 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TFIIIC_delta PF12657.7 EKX36317.1 - 0.055 13.4 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term DUF563 PF04577.14 EKX36318.1 - 1.3e-06 28.7 0.0 2.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Radical_SAM PF04055.21 EKX36319.1 - 1.4e-06 28.8 0.0 2.2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 EKX36319.1 - 0.054 13.6 0.3 0.11 12.6 0.3 1.5 1 0 0 1 1 1 0 4Fe-4S single cluster domain ANAPC10 PF03256.16 EKX36320.1 - 8.5e-68 227.6 0.0 9.4e-68 227.5 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 EKX36320.1 - 0.0014 18.8 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain PITH PF06201.13 EKX36320.1 - 0.0016 18.7 0.1 0.0032 17.7 0.1 1.5 1 1 0 1 1 1 1 PITH domain Chorion_2 PF03964.15 EKX36321.1 - 2.3 9.1 8.0 3.9 8.4 6.7 1.9 2 0 0 2 2 2 0 Chorion family 2 DUF1635 PF07795.11 EKX36321.1 - 2.9 7.7 7.9 16 5.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Myosin_head PF00063.21 EKX36322.1 - 3.3e-134 448.6 3.4 1.1e-133 446.9 3.4 1.7 1 1 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 EKX36322.1 - 0.0071 16.8 0.0 0.019 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EKX36322.1 - 0.012 15.9 0.1 0.056 13.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EKX36322.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Sigma54_activat PF00158.26 EKX36322.1 - 0.14 11.9 0.4 0.91 9.2 0.0 2.3 3 0 0 3 3 3 0 Sigma-54 interaction domain LRR_9 PF14580.6 EKX36323.1 - 3.4e-11 43.0 3.0 4.4e-10 39.3 0.4 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 EKX36323.1 - 1.2e-10 41.4 16.9 0.0002 21.7 0.2 5.1 2 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX36323.1 - 7.5e-07 28.8 0.4 0.00064 19.4 0.1 3.8 2 1 3 5 5 5 4 Leucine rich repeat LRR_6 PF13516.6 EKX36323.1 - 0.093 12.8 0.5 75 3.8 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich repeat UBM PF14377.6 EKX36323.1 - 0.12 11.8 0.2 0.44 10.1 0.2 2.1 1 0 0 1 1 1 0 Ubiquitin binding region DnaJ PF00226.31 EKX36324.1 - 3.6e-21 75.1 0.2 9.3e-21 73.7 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 EKX36324.1 - 4.3e-09 35.8 13.3 0.48 10.3 0.0 6.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 EKX36324.1 - 8.1e-09 34.9 21.2 1.6 9.0 0.0 8.5 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 EKX36324.1 - 5.5e-08 32.4 9.7 1.1 9.7 0.3 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX36324.1 - 1.3e-06 27.9 4.6 0.02 14.6 0.1 3.5 3 1 1 4 4 4 2 TPR repeat TPR_19 PF14559.6 EKX36324.1 - 1.1e-05 25.8 14.6 1.3 9.6 0.4 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX36324.1 - 0.00016 22.2 15.6 0.04 14.6 0.1 5.7 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX36324.1 - 0.0012 19.4 20.6 7.2 7.7 0.1 8.4 7 3 3 10 10 9 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX36324.1 - 0.039 14.1 3.1 8.9 6.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EKX36324.1 - 0.14 12.3 1.8 5.7 7.2 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX36324.1 - 0.55 10.5 17.5 0.44 10.9 0.2 6.1 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 EKX36324.1 - 0.57 11.0 0.0 0.57 11.0 0.0 5.3 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 EKX36324.1 - 1.5 9.3 9.2 1.7 9.2 0.2 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Metallophos PF00149.28 EKX36325.1 - 3.3e-10 40.8 2.9 4.8e-10 40.3 2.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase OapA_N PF08525.11 EKX36325.1 - 0.21 11.6 0.3 0.47 10.5 0.3 1.7 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif LMBR1 PF04791.16 EKX36326.1 - 2.1e-50 172.1 5.6 1.3e-48 166.2 5.6 2.9 1 1 0 1 1 1 1 LMBR1-like membrane protein CRA PF06589.11 EKX36326.1 - 0.15 12.2 1.8 13 5.9 1.2 3.1 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) zf-RING_2 PF13639.6 EKX36329.1 - 3.4e-11 43.3 7.2 3.4e-11 43.3 7.2 1.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 EKX36329.1 - 3.4e-09 36.4 3.8 8.5e-09 35.1 3.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EKX36329.1 - 6.5e-08 32.3 5.5 1.5e-07 31.1 5.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EKX36329.1 - 8.8e-08 31.9 1.4 2.3e-07 30.5 1.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX36329.1 - 3.9e-07 30.2 6.5 1.1e-06 28.9 6.5 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EKX36329.1 - 6e-06 26.0 3.6 6e-06 26.0 3.6 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EKX36329.1 - 1.2e-05 24.9 2.5 1.2e-05 24.9 2.5 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EKX36329.1 - 5.3e-05 23.2 0.9 5.3e-05 23.2 0.9 2.7 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 EKX36329.1 - 6.2e-05 22.9 2.3 6.2e-05 22.9 2.3 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EKX36329.1 - 0.003 17.6 1.0 0.003 17.6 1.0 1.8 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 EKX36329.1 - 0.0054 16.8 3.2 0.016 15.3 3.2 1.9 1 1 0 1 1 1 1 RING-variant domain zf-C3HC4_4 PF15227.6 EKX36329.1 - 0.019 15.1 2.2 0.059 13.5 2.2 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 EKX36329.1 - 0.038 13.6 3.1 0.11 12.1 3.1 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 EKX36329.1 - 0.092 12.6 5.3 0.21 11.4 5.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 EKX36329.1 - 0.22 11.8 2.1 0.73 10.2 2.1 2.0 1 1 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 EKX36329.1 - 0.29 11.3 5.1 1.6 9.0 5.1 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Pex24p PF06398.11 EKX36329.1 - 1.9 7.4 7.8 8.1 5.3 7.8 1.8 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin Guanylate_cyc PF00211.20 EKX36330.1 - 2e-27 96.0 0.1 2.2e-27 95.9 0.1 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Nrap_D5 PF17406.2 EKX36330.1 - 0.077 12.7 0.0 0.099 12.4 0.0 1.1 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 Guanylate_cyc PF00211.20 EKX36331.1 - 6.1e-23 81.4 0.0 6.9e-23 81.2 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Peptidase_M14 PF00246.24 EKX36332.1 - 6.3e-06 26.2 0.1 2.8e-05 24.1 0.1 1.8 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 EKX36332.1 - 0.19 10.8 0.0 0.39 9.7 0.0 1.5 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Pkinase PF00069.25 EKX36333.1 - 1.6e-47 162.1 0.0 2.3e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX36333.1 - 3.1e-37 128.3 0.0 4.6e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX36333.1 - 0.02 14.2 0.0 0.21 10.9 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Glyco_transf_10 PF00852.19 EKX36334.1 - 3.5e-07 30.1 0.0 6.6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term OTU PF02338.19 EKX36336.1 - 7.2e-11 42.7 0.0 1.6e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EKX36336.1 - 0.0053 16.2 0.3 0.96 8.8 0.0 2.7 2 1 1 3 3 3 2 Peptidase C65 Otubain Calreticulin PF00262.18 EKX36337.1 - 1.8e-73 247.5 17.8 1e-52 179.2 8.7 2.6 2 1 1 3 3 3 2 Calreticulin family DivIC PF04977.15 EKX36337.1 - 6.7 6.6 6.5 12 5.7 6.5 1.4 1 0 0 1 1 1 0 Septum formation initiator DNA_pol_phi PF04931.13 EKX36338.1 - 0.015 13.4 44.1 0.021 13.0 44.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 EKX36338.1 - 0.03 12.6 28.2 0.035 12.3 28.2 1.2 1 0 0 1 1 1 0 Nop14-like family DUF3382 PF11862.8 EKX36338.1 - 0.086 13.1 0.9 0.12 12.7 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) NPR3 PF03666.13 EKX36338.1 - 0.15 10.9 1.8 0.17 10.6 1.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RRN3 PF05327.11 EKX36338.1 - 0.19 10.2 25.0 0.22 10.0 25.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop25 PF09805.9 EKX36338.1 - 4.2 7.8 13.4 5.2 7.5 13.4 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF688 PF05097.12 EKX36339.1 - 0.00056 19.2 2.1 0.0012 18.1 2.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF688) DNA_pol_phi PF04931.13 EKX36339.1 - 0.001 17.3 8.6 0.001 17.3 8.6 1.1 1 0 0 1 1 1 1 DNA polymerase phi TLP-20 PF06088.11 EKX36339.1 - 0.0023 17.8 1.6 0.003 17.5 1.6 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Cwf_Cwc_15 PF04889.12 EKX36339.1 - 0.0054 16.5 11.1 0.0093 15.7 11.1 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 EKX36339.1 - 0.0099 15.3 4.2 0.01 15.2 4.2 1.1 1 0 0 1 1 1 1 BUD22 CobT PF06213.12 EKX36339.1 - 0.018 14.5 7.0 0.021 14.2 7.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4820 PF16091.5 EKX36339.1 - 0.018 14.4 0.8 0.023 14.1 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Sigma70_ner PF04546.13 EKX36339.1 - 0.021 14.7 6.4 0.027 14.3 6.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Pox_Ag35 PF03286.14 EKX36339.1 - 0.024 14.5 3.4 0.026 14.3 3.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GCIP PF13324.6 EKX36339.1 - 0.03 13.9 2.4 0.03 14.0 2.4 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Myc_N PF01056.18 EKX36339.1 - 0.045 13.6 3.1 0.057 13.3 3.1 1.1 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.12 EKX36339.1 - 0.051 12.9 14.8 0.065 12.5 14.8 1.1 1 0 0 1 1 1 0 NOA36 protein DUF5520 PF17658.1 EKX36339.1 - 0.094 11.8 1.2 0.096 11.8 1.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5520) Astro_capsid_p PF12226.8 EKX36339.1 - 0.2 10.8 6.6 0.2 10.8 6.6 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein PBP1_TM PF14812.6 EKX36339.1 - 0.26 11.7 12.1 0.4 11.1 12.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC27 PF09507.10 EKX36339.1 - 0.38 10.1 8.4 0.5 9.7 8.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TRAP_alpha PF03896.16 EKX36339.1 - 0.42 9.8 3.3 0.51 9.5 3.3 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2457 PF10446.9 EKX36339.1 - 0.77 8.8 20.4 0.96 8.5 20.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.11 EKX36339.1 - 0.87 9.6 8.4 0.72 9.9 7.1 1.6 2 0 0 2 2 2 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 EKX36339.1 - 0.89 10.0 17.3 1.6 9.2 17.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.12 EKX36339.1 - 1.1 7.3 13.7 1.6 6.9 13.7 1.2 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 EKX36339.1 - 3.6 7.2 12.6 9.1 5.9 12.6 1.7 1 1 0 1 1 1 0 FAM176 family DUF2722 PF10846.8 EKX36339.1 - 3.9 6.3 7.6 5.3 5.9 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SDA1 PF05285.12 EKX36339.1 - 4.2 6.7 14.3 5.1 6.4 14.3 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 EKX36339.1 - 5.7 5.1 14.1 8.5 4.5 14.1 1.2 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 EKX36339.1 - 8.2 6.5 14.4 10 6.1 14.4 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Prok-E2_C PF14459.6 EKX36340.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family C PCI PF01399.27 EKX36341.1 - 1.2e-08 35.4 0.0 1.8e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 PCI domain Herpes_LMP1 PF05297.11 EKX36341.1 - 5.6 6.0 11.6 5.5 6.1 11.6 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DSPc PF00782.20 EKX36342.1 - 1.7e-23 82.9 0.0 2.1e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX36342.1 - 0.00066 19.3 0.0 0.00095 18.8 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Pkinase PF00069.25 EKX36343.1 - 2.5e-43 148.3 0.0 3.3e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX36343.1 - 7.9e-41 140.1 0.0 2.2e-40 138.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX36343.1 - 3e-05 23.0 0.0 4.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EKX36343.1 - 0.023 14.3 0.0 0.053 13.1 0.0 1.6 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EKX36343.1 - 0.033 14.1 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family SH3_2 PF07653.17 EKX36344.1 - 0.0012 18.5 0.0 0.0024 17.5 0.0 1.5 1 1 0 1 1 1 1 Variant SH3 domain DUF3104 PF11302.8 EKX36344.1 - 0.035 13.8 0.2 0.2 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3104) SH3_1 PF00018.28 EKX36344.1 - 0.066 12.8 0.0 1 9.0 0.0 2.4 2 0 0 2 2 2 0 SH3 domain SH3_9 PF14604.6 EKX36344.1 - 0.079 12.8 0.0 8.7 6.3 0.0 2.9 3 0 0 3 3 3 0 Variant SH3 domain DUF5641 PF18701.1 EKX36344.1 - 0.17 12.1 0.0 3.8 7.7 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5641) Ion_trans PF00520.31 EKX36347.1 - 1.3e-21 77.0 10.3 2.7e-13 49.7 8.4 2.2 2 0 0 2 2 2 2 Ion transport protein CDC45 PF02724.14 EKX36347.1 - 8.6e-06 24.3 0.1 8.6e-06 24.3 0.1 2.1 2 1 0 2 2 2 1 CDC45-like protein DNA_pol_phi PF04931.13 EKX36347.1 - 2.2e-05 22.8 14.8 2.2e-05 22.8 14.8 2.4 3 0 0 3 3 3 1 DNA polymerase phi PKD_channel PF08016.12 EKX36347.1 - 0.0095 14.7 7.6 0.015 14.0 7.6 1.2 1 0 0 1 1 1 1 Polycystin cation channel Pes-10 PF07149.11 EKX36347.1 - 0.012 14.7 4.9 0.035 13.2 4.9 1.8 1 0 0 1 1 1 0 Pes-10 LRR_9 PF14580.6 EKX36348.1 - 2.5e-09 36.9 0.2 4.1e-09 36.2 0.2 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 EKX36348.1 - 6.4e-09 35.5 0.5 2.3e-07 30.4 0.1 2.7 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 EKX36348.1 - 1.3e-07 31.8 1.3 0.00056 20.3 0.2 3.5 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) EURL PF06937.11 EKX36352.1 - 0.11 11.8 1.0 0.17 11.2 1.0 1.2 1 0 0 1 1 1 0 EURL protein DUF2877 PF11392.8 EKX36355.1 - 0.073 13.8 0.1 0.14 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2877) MAJIN PF15077.6 EKX36356.1 - 0.094 12.5 5.1 0.11 12.2 5.1 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein FAM76 PF16046.5 EKX36356.1 - 0.17 11.2 2.4 0.2 11.0 2.4 1.1 1 0 0 1 1 1 0 FAM76 protein LRR_4 PF12799.7 EKX36360.1 - 9.8e-12 44.9 27.8 0.00025 21.3 7.1 4.4 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX36360.1 - 0.0016 18.1 29.0 0.017 14.9 6.5 3.4 2 1 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 EKX36360.1 - 0.0051 16.3 5.2 0.031 13.8 2.4 2.2 1 1 1 2 2 2 2 Leucine-rich repeat ketoacyl-synt PF00109.26 EKX36361.1 - 1.1e-35 123.4 0.6 1.5e-35 123.0 0.6 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EKX36361.1 - 2.4e-28 98.5 1.1 7e-28 97.0 0.2 2.3 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EKX36361.1 - 0.092 13.2 0.0 0.47 10.9 0.0 2.2 2 0 0 2 2 2 0 Ketoacyl-synthetase C-terminal extension AP-5_subunit_s1 PF15001.6 EKX36363.1 - 0.51 10.3 5.4 0.58 10.1 0.0 2.4 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 COesterase PF00135.28 EKX36364.1 - 5.5e-16 58.5 4.4 1.2e-08 34.3 0.0 3.2 3 1 1 4 4 4 2 Carboxylesterase family DUF3713 PF12506.8 EKX36364.1 - 1.5 9.2 4.7 17 5.8 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) DUF4647 PF15504.6 EKX36365.1 - 0.045 12.9 0.2 0.053 12.6 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) V_ATPase_I PF01496.19 EKX36366.1 - 9.1e-07 27.2 5.1 9.1e-07 27.2 5.1 1.5 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family CBP_BcsG PF11658.8 EKX36366.1 - 7.3e-05 21.4 0.5 0.00012 20.7 0.5 1.4 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsG SpoIIIAH PF12685.7 EKX36366.1 - 0.00024 21.0 15.9 0.00024 21.0 15.9 1.8 1 1 1 2 2 2 1 SpoIIIAH-like protein SID-1_RNA_chan PF13965.6 EKX36366.1 - 0.00033 19.2 4.1 0.00033 19.2 4.1 2.0 1 1 1 2 2 1 1 dsRNA-gated channel SID-1 DUF913 PF06025.12 EKX36366.1 - 0.0017 17.4 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) YfhO PF09586.10 EKX36366.1 - 0.0036 15.6 0.1 0.0039 15.5 0.1 1.0 1 0 0 1 1 1 1 Bacterial membrane protein YfhO SARAF PF06682.12 EKX36366.1 - 0.005 16.5 0.0 0.005 16.5 0.0 1.9 1 1 1 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis PHO4 PF01384.20 EKX36366.1 - 0.011 14.8 0.0 0.012 14.7 0.0 1.1 1 0 0 1 1 1 0 Phosphate transporter family RRN3 PF05327.11 EKX36366.1 - 0.13 10.8 17.3 0.13 10.8 17.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 O-antigen_lig PF13425.6 EKX36366.1 - 0.18 10.6 32.5 1.4 7.7 32.5 2.0 1 1 0 1 1 1 0 O-antigen ligase like membrane protein OPA3 PF07047.12 EKX36366.1 - 0.56 10.0 0.1 0.56 10.0 0.1 2.7 1 1 1 2 2 1 0 Optic atrophy 3 protein (OPA3) Chitin_synth_2 PF03142.15 EKX36366.1 - 0.61 8.6 9.6 0.68 8.5 9.6 1.2 1 0 0 1 1 1 0 Chitin synthase Tombus_P33 PF08500.10 EKX36366.1 - 1.1 9.2 4.1 0.79 9.7 2.4 1.6 1 1 0 1 1 1 0 Tombusvirus p33 FAM176 PF14851.6 EKX36366.1 - 2.7 7.7 30.5 4.5e+03 -2.8 28.9 2.5 1 1 0 1 1 1 0 FAM176 family DUF3328 PF11807.8 EKX36366.1 - 4.1 7.1 9.5 1.8e+02 1.7 9.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) CbiQ PF02361.16 EKX36366.1 - 4.2 6.9 19.7 5.4 6.6 19.7 1.1 1 0 0 1 1 1 0 Cobalt transport protein TRAP_alpha PF03896.16 EKX36366.1 - 5.5 6.1 24.2 0.3 10.3 16.5 2.1 1 1 1 2 2 1 0 Translocon-associated protein (TRAP), alpha subunit Peptidase_C14 PF00656.22 EKX36367.1 - 2.1e-12 47.5 0.0 3.6e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Caspase domain PSK_trans_fac PF07704.11 EKX36367.1 - 0.54 11.0 6.9 9.6 7.0 3.7 3.3 2 0 0 2 2 2 0 Rv0623-like transcription factor ANAPC4_WD40 PF12894.7 EKX36369.1 - 3.6e-10 40.0 0.0 0.00012 22.3 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EKX36369.1 - 1.1e-05 26.1 0.4 0.22 12.4 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.8 EKX36369.1 - 3.4e-05 22.7 0.0 0.0025 16.5 0.0 2.3 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Pentapeptide PF00805.22 EKX36369.1 - 3.8e-05 23.2 0.0 0.00019 21.0 0.0 2.1 1 1 0 1 1 1 1 Pentapeptide repeats (8 copies) NACHT PF05729.12 EKX36369.1 - 0.00033 20.6 0.0 0.0053 16.7 0.0 2.2 1 1 0 1 1 1 1 NACHT domain Tox-HDC PF15656.6 EKX36369.1 - 0.00089 19.5 0.0 0.0022 18.2 0.0 1.7 1 0 0 1 1 1 1 Toxin with a H, D/N and C signature AAA_16 PF13191.6 EKX36369.1 - 0.0055 17.1 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EKX36369.1 - 0.021 14.8 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 EKX36369.1 - 0.041 14.4 0.1 0.21 12.1 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Ge1_WD40 PF16529.5 EKX36369.1 - 0.048 12.6 0.0 0.11 11.4 0.0 1.6 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_30 PF13604.6 EKX36369.1 - 0.052 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EKX36369.1 - 0.084 13.0 0.4 0.28 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EKX36369.1 - 0.11 12.8 0.0 0.34 11.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain PD40 PF07676.12 EKX36369.1 - 0.11 12.5 0.0 30 4.7 0.0 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.11 EKX36369.1 - 0.15 10.7 0.0 7.1 5.3 0.0 2.1 2 0 0 2 2 2 0 Nup133 N terminal like Peptidase_C14 PF00656.22 EKX36371.1 - 8.7e-14 52.1 0.0 1.4e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Caspase domain PHP_C PF13263.6 EKX36375.1 - 0.086 12.6 0.0 0.21 11.4 0.0 1.7 2 0 0 2 2 2 0 PHP-associated SPX PF03105.19 EKX36375.1 - 0.31 10.9 0.9 0.45 10.4 0.9 1.4 1 1 0 1 1 1 0 SPX domain RRN3 PF05327.11 EKX36376.1 - 0.2 10.1 8.7 0.24 9.9 8.7 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TAF PF02969.17 EKX36377.1 - 0.046 13.9 3.4 0.18 12.0 3.4 2.1 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) Asp PF00026.23 EKX36378.1 - 3.6e-29 102.2 0.0 2.5e-20 73.1 0.0 2.4 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EKX36378.1 - 2.5e-07 31.1 0.0 0.021 15.1 0.0 2.5 2 0 0 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EKX36378.1 - 0.026 15.2 1.1 18 6.0 0.0 4.2 4 1 0 4 4 4 0 Aspartyl protease MgtE_N PF03448.17 EKX36378.1 - 0.043 14.4 0.1 0.11 13.1 0.1 1.7 1 0 0 1 1 1 0 MgtE intracellular N domain PGA2 PF07543.12 EKX36379.1 - 4.6 7.2 10.6 4.6 7.2 8.9 1.7 1 1 1 2 2 2 0 Protein trafficking PGA2 C2 PF00168.30 EKX36383.1 - 8.4e-30 103.1 0.0 1.9e-16 60.2 0.0 2.5 2 0 0 2 2 2 2 C2 domain LRR_6 PF13516.6 EKX36383.1 - 0.00067 19.5 6.6 1.7 8.9 0.1 4.0 4 0 0 4 4 4 2 Leucine Rich repeat XRCC4 PF06632.12 EKX36383.1 - 0.1 11.4 3.7 4.4 6.0 3.0 2.2 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Utp21 PF04192.12 EKX36383.1 - 0.12 11.9 0.0 0.12 11.9 0.0 2.3 1 1 0 2 2 2 0 Utp21 specific WD40 associated putative domain Lin-8 PF03353.15 EKX36383.1 - 0.34 10.4 4.0 0.56 9.7 4.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RCC1_2 PF13540.6 EKX36384.1 - 3.1e-16 58.7 0.9 2.6e-09 36.6 0.1 2.3 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EKX36384.1 - 4.8e-11 43.1 0.2 2.5e-05 24.8 0.0 3.0 3 1 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat GhoS PF11080.8 EKX36384.1 - 0.025 14.5 0.0 6.5 6.8 0.0 2.4 2 0 0 2 2 2 0 Endoribonuclease GhoS MAGE PF01454.19 EKX36385.1 - 4.2e-25 88.7 0.3 7e-25 88.0 0.3 1.3 1 0 0 1 1 1 1 MAGE family polyprenyl_synt PF00348.17 EKX36387.1 - 2.8e-23 82.3 0.9 4e-23 81.8 0.9 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 EKX36387.1 - 0.0053 16.4 0.0 0.013 15.1 0.0 1.7 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 EF-hand_1 PF00036.32 EKX36388.1 - 3.7e-20 69.9 2.0 1.8e-07 30.2 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EKX36388.1 - 3.7e-18 63.8 7.7 1.2e-08 34.2 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 EKX36388.1 - 4.1e-18 65.6 4.9 1.3e-13 51.2 0.5 2.5 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 EKX36388.1 - 2.7e-16 59.1 6.7 3.8e-11 42.7 0.4 4.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EKX36388.1 - 1.9e-12 46.0 7.7 1.8e-05 24.0 0.1 3.9 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 EKX36388.1 - 9.2e-07 29.1 0.1 5.5e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_11 PF08976.11 EKX36388.1 - 0.0083 17.0 0.0 0.19 12.6 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 EKX36388.1 - 0.01 15.8 0.7 0.038 13.9 0.4 2.0 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand ERAP1_C PF11838.8 EKX36388.1 - 0.016 14.7 0.0 0.074 12.6 0.0 1.8 1 1 0 1 1 1 0 ERAP1-like C-terminal domain TerB PF05099.13 EKX36388.1 - 0.062 13.3 0.0 0.19 11.7 0.0 1.8 1 1 1 2 2 2 0 Tellurite resistance protein TerB PMBR PF09373.10 EKX36388.1 - 0.17 12.1 0.1 75 3.7 0.0 3.3 3 0 0 3 3 3 0 Pseudomurein-binding repeat Sacchrp_dh_NADP PF03435.18 EKX36389.1 - 1.7e-13 51.0 0.1 2e-13 50.7 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 EKX36389.1 - 0.00034 21.0 0.0 0.00047 20.6 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 EKX36389.1 - 0.0024 17.3 0.0 0.003 17.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EKX36389.1 - 0.0069 16.3 0.0 0.0087 16.0 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EKX36389.1 - 0.016 15.1 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 EKX36389.1 - 0.057 12.6 0.0 0.071 12.2 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Lig_chan PF00060.26 EKX36391.1 - 1.1e-14 54.6 0.0 2.5e-14 53.3 0.0 1.7 1 1 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 EKX36391.1 - 0.0014 18.1 0.0 0.063 12.7 0.0 3.1 2 1 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 Somatomedin_B PF01033.17 EKX36391.1 - 2 8.9 9.1 5.1 7.6 9.1 1.7 1 0 0 1 1 1 0 Somatomedin B domain Glyco_hydro_77 PF02446.17 EKX36392.1 - 9.4e-100 334.7 0.1 1.4e-99 334.1 0.1 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.19 EKX36392.1 - 1.4e-11 44.1 0.1 8.4e-05 22.4 0.0 3.0 2 1 0 2 2 2 2 Starch binding domain PHTB1_N PF14727.6 EKX36393.1 - 2.8e-05 23.7 0.1 0.00012 21.6 0.1 1.8 2 0 0 2 2 2 1 PTHB1 N-terminus Vezatin PF12632.7 EKX36393.1 - 0.11 11.9 1.8 0.53 9.6 0.3 2.1 2 0 0 2 2 2 0 Mysoin-binding motif of peroxisomes Ribosomal_S17e PF00833.18 EKX36394.1 - 2.1e-61 205.3 1.8 2.4e-61 205.1 1.8 1.0 1 0 0 1 1 1 1 Ribosomal S17 Kelch_1 PF01344.25 EKX36396.1 - 2.2e-09 36.8 0.7 9.6e-06 25.1 0.0 2.7 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 EKX36396.1 - 2.2e-09 37.3 0.1 0.00011 22.4 0.0 2.5 1 1 1 2 2 2 2 Kelch motif Kelch_5 PF13854.6 EKX36396.1 - 0.00062 19.7 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 Kelch motif Kelch_3 PF13415.6 EKX36396.1 - 0.0017 18.6 0.0 3 8.2 0.0 3.0 2 0 0 2 2 2 2 Galactose oxidase, central domain TFIIE-A_C PF11521.8 EKX36396.1 - 0.0018 18.6 6.4 0.082 13.2 2.3 2.5 2 0 0 2 2 2 2 C-terminal general transcription factor TFIIE alpha RR_TM4-6 PF06459.12 EKX36396.1 - 0.041 13.7 2.5 0.065 13.1 2.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Kelch_2 PF07646.15 EKX36396.1 - 0.047 13.7 0.5 4.7 7.3 0.3 2.9 2 1 0 2 2 2 0 Kelch motif DUF3682 PF12446.8 EKX36396.1 - 5.2 7.6 12.4 2.4 8.7 2.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) zf-RING_2 PF13639.6 EKX36397.1 - 6.5e-11 42.4 6.5 6.5e-11 42.4 6.5 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EKX36397.1 - 8e-08 32.0 4.3 2.5e-07 30.4 4.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX36397.1 - 1e-06 28.9 9.8 1e-06 28.9 9.8 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EKX36397.1 - 1.5e-06 27.9 7.3 3.3e-06 26.8 6.3 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EKX36397.1 - 2.2e-05 24.1 1.4 6.8e-05 22.5 1.4 1.9 1 0 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 EKX36397.1 - 0.00027 20.5 5.4 0.00027 20.5 5.4 2.1 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EKX36397.1 - 0.00031 20.7 3.4 0.00088 19.3 3.4 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EKX36397.1 - 0.0012 18.6 7.4 0.0012 18.6 7.4 2.7 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EKX36397.1 - 0.0042 17.1 3.6 0.012 15.7 3.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.8 EKX36397.1 - 0.38 11.0 6.2 1.5 9.0 6.2 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain TPR_19 PF14559.6 EKX36398.1 - 6.3e-05 23.4 4.5 0.33 11.5 0.2 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX36398.1 - 0.01 16.1 1.2 2.1 8.6 0.1 3.2 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EKX36398.1 - 0.034 14.8 1.5 28 5.6 0.1 3.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX36398.1 - 0.13 12.6 6.1 0.88 10.0 0.1 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EKX36398.1 - 0.14 12.4 9.6 2.6 8.4 0.1 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX36398.1 - 0.17 12.7 2.5 30 5.8 0.0 3.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EKX36398.1 - 0.18 11.5 2.0 0.67 9.7 0.0 2.7 4 0 0 4 4 4 0 TPR repeat TPR_1 PF00515.28 EKX36398.1 - 2.8 7.9 6.6 4.4 7.3 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DSPc PF00782.20 EKX36399.1 - 1.4e-05 24.9 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 EKX36399.1 - 8.9e-05 22.2 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 EKX36399.1 - 0.00048 20.2 0.1 0.00076 19.5 0.1 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EKX36399.1 - 0.008 15.8 0.0 0.0098 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DEAD PF00270.29 EKX36399.1 - 0.011 15.6 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase PTPlike_phytase PF14566.6 EKX36399.1 - 0.015 15.5 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate FIST_C PF10442.9 EKX36400.1 - 1.6e-10 41.0 0.0 4.8e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 FIST C domain FIST PF08495.10 EKX36400.1 - 6e-08 32.9 0.1 2.5e-06 27.6 0.1 2.9 3 2 0 3 3 3 1 FIST N domain Carb_anhydrase PF00194.21 EKX36401.1 - 1.5e-23 83.7 0.0 3.2e-23 82.6 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase GETHR PF05671.11 EKX36401.1 - 0.08 12.3 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 GETHR pentapeptide repeat (5 copies) Glutaredoxin PF00462.24 EKX36402.1 - 0.031 14.5 0.0 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin KAP PF05804.12 EKX36403.1 - 4.1e-206 686.4 23.2 5e-206 686.1 23.2 1.0 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Arm PF00514.23 EKX36403.1 - 2.3e-07 30.6 0.3 1.1 9.5 0.0 6.1 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat Spore_III_AE PF09546.10 EKX36403.1 - 0.053 12.7 0.3 0.11 11.6 0.3 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AE (spore_III_AE) FPL PF09758.9 EKX36403.1 - 0.3 11.1 7.9 0.12 12.4 1.3 3.4 3 0 0 3 3 3 0 Uncharacterised conserved protein Ion_trans PF00520.31 EKX36405.1 - 2.7e-13 49.7 8.9 4.7e-13 48.9 8.9 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 EKX36405.1 - 3.6e-13 49.4 0.0 6.5e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EKX36405.1 - 3.5e-12 46.1 9.9 3.5e-12 46.1 9.9 2.4 2 1 0 2 2 2 1 Ion channel IRK PF01007.20 EKX36405.1 - 0.0059 16.4 4.0 0.016 15.0 4.0 1.7 1 0 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain PA PF02225.22 EKX36406.1 - 3.4e-12 46.2 0.1 6.7e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 PA domain CRS1_YhbY PF01985.21 EKX36406.1 - 4.3e-07 30.0 3.4 4.8e-07 29.9 1.7 2.0 2 1 0 2 2 2 1 CRS1 / YhbY (CRM) domain SepF PF04472.12 EKX36406.1 - 0.028 14.7 0.3 0.13 12.5 0.1 2.3 3 0 0 3 3 3 0 Cell division protein SepF Viral_DNA_bp PF00747.17 EKX36406.1 - 0.15 9.2 0.3 0.18 8.9 0.3 1.0 1 0 0 1 1 1 0 ssDNA binding protein SecD-TM1 PF13721.6 EKX36406.1 - 0.21 12.1 1.0 0.88 10.1 0.3 2.0 2 0 0 2 2 2 0 SecD export protein N-terminal TM region RWP-RK PF02042.15 EKX36407.1 - 3.5e-13 49.3 0.1 5.1e-13 48.8 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain SRCR PF00530.18 EKX36407.1 - 0.013 16.0 0.0 0.014 15.9 0.0 1.1 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain RWP-RK PF02042.15 EKX36408.1 - 1.5e-15 56.9 0.0 2.7e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_6 PF01418.17 EKX36408.1 - 0.0076 16.2 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family Carbam_trans_C PF16861.5 EKX36408.1 - 0.01 15.5 0.1 0.013 15.0 0.1 1.1 1 0 0 1 1 1 0 Carbamoyltransferase C-terminus ClpS PF02617.17 EKX36408.1 - 0.037 13.8 0.2 0.056 13.2 0.2 1.3 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS RWP-RK PF02042.15 EKX36409.1 - 1e-15 57.4 0.1 1.7e-15 56.7 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_6 PF01418.17 EKX36409.1 - 0.0044 17.0 0.0 0.0083 16.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family Polyoma_lg_T_C PF06431.11 EKX36409.1 - 0.23 10.3 2.1 0.3 9.9 2.1 1.1 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus Sporozoite_P67 PF05642.11 EKX36409.1 - 0.46 8.5 4.7 0.55 8.2 4.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RWP-RK PF02042.15 EKX36410.1 - 5.2e-12 45.5 0.0 8.7e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_6 PF01418.17 EKX36410.1 - 0.008 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family RWP-RK PF02042.15 EKX36411.1 - 4.4e-13 49.0 0.0 1.1e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 RWP-RK domain CHAD PF05235.14 EKX36411.1 - 0.038 13.9 0.0 0.043 13.8 0.0 1.1 1 0 0 1 1 1 0 CHAD domain CHORD PF04968.12 EKX36412.1 - 2.8e-23 82.4 12.4 6.8e-23 81.2 12.4 1.7 1 0 0 1 1 1 1 CHORD TPR_1 PF00515.28 EKX36412.1 - 5.2e-15 54.5 0.2 1.8e-05 24.3 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat CS PF04969.16 EKX36412.1 - 6.3e-13 49.6 0.0 1.2e-12 48.7 0.0 1.5 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 EKX36412.1 - 3.8e-12 45.3 0.2 3.2e-05 23.7 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX36412.1 - 5e-08 32.8 0.0 0.0086 16.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX36412.1 - 7.8e-08 32.0 0.0 0.0045 17.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX36412.1 - 9.4e-08 31.6 0.0 2.9e-05 23.7 0.0 3.1 1 1 2 3 3 3 2 TPR repeat TPR_19 PF14559.6 EKX36412.1 - 1e-07 32.4 0.6 2.5e-05 24.7 0.1 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX36412.1 - 1.7e-06 28.6 0.1 3.5e-05 24.4 0.1 2.3 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX36412.1 - 2.8e-05 24.6 0.2 1.4 9.9 0.2 3.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX36412.1 - 0.0026 17.7 0.1 7.1 6.9 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX36412.1 - 0.006 16.8 0.3 3.1 8.2 0.1 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX36412.1 - 0.012 15.8 0.0 0.03 14.5 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EKX36412.1 - 0.019 14.4 0.0 0.037 13.4 0.0 1.5 1 1 0 1 1 1 0 MalT-like TPR region HemY_N PF07219.13 EKX36412.1 - 0.031 14.5 3.6 0.2 11.9 0.2 2.8 3 0 0 3 3 3 0 HemY protein N-terminus NARP1 PF12569.8 EKX36412.1 - 0.033 13.1 0.0 0.17 10.8 0.0 1.8 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 EKX36412.1 - 0.057 13.6 0.0 0.3 11.3 0.0 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat Sel1 PF08238.12 EKX36412.1 - 0.2 12.4 1.8 7.9 7.3 0.1 3.1 2 1 1 3 3 2 0 Sel1 repeat PPR_2 PF13041.6 EKX36412.1 - 0.84 9.9 2.7 1.3e+02 2.9 0.0 4.4 5 1 0 5 5 4 0 PPR repeat family Pkinase_Tyr PF07714.17 EKX36413.1 - 4e-57 193.4 0.0 5.3e-57 193.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX36413.1 - 3.4e-52 177.4 0.0 4.2e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EKX36413.1 - 7.5e-05 22.2 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EKX36413.1 - 0.00037 19.9 0.2 0.00075 18.9 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EKX36413.1 - 0.0035 16.3 0.1 0.0051 15.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EKX36413.1 - 0.004 17.1 0.6 0.054 13.4 0.1 2.7 1 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX36413.1 - 0.043 12.6 0.0 0.072 11.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EKX36413.1 - 0.062 12.8 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 EKX36413.1 - 0.085 12.5 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 RIO1 family PDZ PF00595.24 EKX36414.1 - 3.9e-05 23.9 0.2 9.7e-05 22.6 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX36414.1 - 0.013 15.4 0.1 0.048 13.5 0.1 2.1 1 0 0 1 1 1 0 PDZ domain Ribosomal_60s PF00428.19 EKX36414.1 - 0.19 12.3 6.0 1.1 9.9 6.0 2.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4988 PF16378.5 EKX36414.1 - 0.6 9.8 2.5 19 4.9 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF1664 PF07889.12 EKX36414.1 - 5 7.2 21.4 0.087 12.9 1.7 4.3 3 2 3 6 6 6 0 Protein of unknown function (DUF1664) PDZ PF00595.24 EKX36416.1 - 8.9e-09 35.6 0.0 1.5e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX36416.1 - 7.9e-08 32.0 0.1 1.4e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX36416.1 - 0.00013 22.2 0.5 0.00028 21.2 0.2 1.7 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 EKX36416.1 - 0.0036 17.2 0.1 0.0085 16.0 0.1 1.5 1 0 0 1 1 1 1 Tricorn protease PDZ domain CPT PF07931.12 EKX36418.1 - 0.0082 16.0 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein FA_desaturase PF00487.24 EKX36419.1 - 4.1e-33 115.3 24.7 4.1e-33 115.3 24.7 2.0 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 EKX36419.1 - 5.3e-22 77.7 0.1 1.1e-21 76.7 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Flavodoxin_2 PF02525.17 EKX36421.1 - 8.3e-27 94.2 0.0 9.8e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 EKX36421.1 - 1.3e-09 37.9 0.0 1.8e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Med26_M PF15694.5 EKX36422.1 - 0.02 15.0 1.3 0.021 14.9 1.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 26 middle domain XG_FTase PF03254.13 EKX36423.1 - 0.12 11.0 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Xyloglucan fucosyltransferase BLM_N PF16202.5 EKX36425.1 - 0.028 13.6 1.6 0.032 13.3 1.6 1.1 1 0 0 1 1 1 0 N-terminal region of Bloom syndrome protein PBP1_TM PF14812.6 EKX36425.1 - 0.048 14.0 4.1 0.068 13.6 4.1 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 EKX36425.1 - 0.06 13.0 4.4 0.072 12.8 4.4 1.1 1 0 0 1 1 1 0 FAM176 family DAP PF15228.6 EKX36425.1 - 0.13 13.5 0.1 0.18 13.0 0.1 1.2 1 0 0 1 1 1 0 Death-associated protein DUF3682 PF12446.8 EKX36425.1 - 0.14 12.6 9.3 0.2 12.1 9.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) CENP-B_dimeris PF09026.10 EKX36425.1 - 0.95 9.9 12.1 1.5 9.2 12.1 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.14 EKX36425.1 - 0.99 7.6 4.1 1.2 7.4 4.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 EKX36425.1 - 2.4 7.9 7.2 3.1 7.5 7.2 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DNA_pol_phi PF04931.13 EKX36425.1 - 2.5 6.1 9.1 3 5.8 9.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi Nucleo_P87 PF07267.11 EKX36425.1 - 7.1 5.3 5.8 9 5.0 5.8 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 WD40 PF00400.32 EKX36426.1 - 5.7e-51 169.4 20.4 3.7e-08 33.9 0.2 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX36426.1 - 1.8e-28 98.7 3.4 1.2e-06 28.7 0.0 6.2 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 EKX36426.1 - 6.4e-12 45.0 0.7 1.1e-11 44.2 0.7 1.4 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 EKX36426.1 - 1.2e-09 38.3 2.0 0.007 16.3 0.2 4.1 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EKX36426.1 - 5.1e-06 26.0 0.0 0.11 11.9 0.0 3.8 2 1 0 4 4 4 2 WD40-like domain Nup160 PF11715.8 EKX36426.1 - 0.0025 16.5 2.3 4.2 5.9 0.0 4.2 2 2 1 4 4 4 1 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.14 EKX36426.1 - 0.013 14.6 4.1 4.7 6.1 0.0 4.1 3 2 1 4 4 4 0 Coatomer WD associated region RAB3GAP2_N PF14655.6 EKX36426.1 - 0.061 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus ASH PF15780.5 EKX36426.1 - 0.23 11.7 1.5 0.63 10.3 0.1 2.4 3 0 0 3 3 3 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin THF_DHG_CYH_C PF02882.19 EKX36430.1 - 2e-62 209.2 1.6 3e-62 208.6 1.6 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EKX36430.1 - 2.9e-35 121.0 0.4 4.6e-35 120.4 0.4 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain K_oxygenase PF13434.6 EKX36430.1 - 0.2 10.8 0.1 0.37 9.9 0.1 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Beta_lactamase3 PF17030.5 EKX36432.1 - 0.028 13.7 0.1 0.044 13.0 0.1 1.3 1 0 0 1 1 1 0 Putative beta-lactamase-like family CRAL_TRIO PF00650.20 EKX36432.1 - 0.09 12.5 0.0 0.18 11.5 0.0 1.5 2 0 0 2 2 2 0 CRAL/TRIO domain CDC37_N PF03234.14 EKX36432.1 - 0.12 13.3 0.0 0.16 12.9 0.0 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding SRP68 PF16969.5 EKX36433.1 - 1.8e-127 426.7 1.7 2e-127 426.5 1.7 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 TPR_1 PF00515.28 EKX36433.1 - 0.02 14.7 0.2 0.13 12.1 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EKX36433.1 - 0.032 14.4 3.3 0.09 12.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX36433.1 - 0.045 14.0 2.5 2.4 8.5 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DXP_redisom_C PF08436.12 EKX36433.1 - 0.16 12.2 0.0 0.47 10.6 0.0 1.8 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain DUF4131 PF13567.6 EKX36433.1 - 1.7 8.3 10.7 3.1 7.4 10.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) TPR_6 PF13174.6 EKX36433.1 - 2.1 9.2 4.1 9.9 7.0 0.3 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat HECT PF00632.25 EKX36434.1 - 6.8e-83 278.7 0.3 1.6e-80 270.8 0.3 2.1 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF4224 PF13986.6 EKX36434.1 - 0.17 11.8 0.2 0.84 9.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) ubiquitin PF00240.23 EKX36435.1 - 6.3e-06 25.9 0.0 0.005 16.6 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin family PORR PF11955.8 EKX36436.1 - 0.0067 15.4 0.0 1.9 7.4 0.0 2.1 2 0 0 2 2 2 2 Plant organelle RNA recognition domain zf-CCHC PF00098.23 EKX36436.1 - 0.15 12.2 17.0 0.4 10.8 2.5 3.4 3 0 0 3 3 3 0 Zinc knuckle OST-HTH PF12872.7 EKX36436.1 - 0.24 11.3 0.3 9.2 6.2 0.0 3.2 4 0 0 4 4 4 0 OST-HTH/LOTUS domain zf-CCHC_4 PF14392.6 EKX36436.1 - 8.4 6.2 18.5 0.84 9.4 0.8 3.4 2 1 1 3 3 3 0 Zinc knuckle Peptidase_M14 PF00246.24 EKX36437.1 - 3.6e-15 56.5 0.0 1.2e-14 54.8 0.0 1.9 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 EKX36437.1 - 1.7e-09 38.0 0.0 3.4e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 EKX36437.1 - 0.017 14.2 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family HEAT_2 PF13646.6 EKX36439.1 - 2.8e-08 34.0 0.0 0.00035 20.9 0.0 2.9 1 1 1 3 3 3 2 HEAT repeats Arm PF00514.23 EKX36439.1 - 1e-07 31.7 1.5 0.042 13.9 0.2 3.8 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EKX36439.1 - 1.6e-05 24.8 3.6 7.8e-05 22.6 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 EKX36439.1 - 0.35 11.4 1.7 5.8 7.5 0.0 3.3 2 1 2 4 4 4 0 HEAT-like repeat TylF PF05711.11 EKX36440.1 - 9.1e-32 110.3 0.0 2.1e-31 109.2 0.0 1.6 1 1 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.6 EKX36440.1 - 3.2e-06 28.1 0.0 9.8e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain pPIWI_RE_Y PF18156.1 EKX36440.1 - 0.0044 17.4 0.2 0.0082 16.6 0.2 1.4 1 0 0 1 1 1 1 pPIWI_RE three-gene island domain Y DUF842 PF05811.13 EKX36440.1 - 0.99 9.1 3.7 1.2 8.9 0.3 2.4 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF842) TMEM154 PF15102.6 EKX36441.1 - 0.005 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family DUF4834 PF16118.5 EKX36441.1 - 0.0054 17.7 0.0 0.0054 17.7 0.0 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4834) CSTF_C PF14304.6 EKX36441.1 - 0.035 13.7 1.6 0.094 12.3 1.6 1.6 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal FAM176 PF14851.6 EKX36441.1 - 0.52 10.0 5.2 0.29 10.8 0.8 2.4 2 1 1 3 3 3 0 FAM176 family TylF PF05711.11 EKX36442.1 - 1.5e-10 40.8 1.0 2.6e-10 40.0 0.6 1.6 1 1 1 2 2 2 1 Macrocin-O-methyltransferase (TylF) MAJIN PF15077.6 EKX36443.1 - 0.39 10.5 7.6 0.64 9.8 7.6 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein Methyltransf_11 PF08241.12 EKX36444.1 - 8.4e-12 45.6 0.0 1.9e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX36444.1 - 1.4e-10 41.7 0.0 3.1e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX36444.1 - 4.7e-06 26.1 0.0 1.2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EKX36444.1 - 8.3e-06 25.7 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EKX36444.1 - 1e-05 25.5 0.0 2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_12 PF08242.12 EKX36444.1 - 9.4e-05 23.1 0.0 0.0002 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX36444.1 - 0.00043 20.2 0.0 0.0012 18.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Mannosyl_trans3 PF11051.8 EKX36444.1 - 0.0045 16.4 0.0 0.0071 15.7 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Methyltransf_29 PF03141.16 EKX36444.1 - 0.042 12.4 0.0 0.06 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ank_4 PF13637.6 EKX36445.1 - 1.4e-08 35.1 0.0 1.5e-05 25.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX36445.1 - 4.7e-08 33.5 0.0 5.4e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX36445.1 - 4.3e-06 26.9 0.1 5.9e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX36445.1 - 1.5e-05 25.3 0.4 4e-05 23.8 0.1 1.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EKX36445.1 - 3e-05 24.0 0.0 0.00041 20.6 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeat Aquarius_N PF16399.5 EKX36445.1 - 0.074 11.1 0.0 0.076 11.1 0.0 1.0 1 0 0 1 1 1 0 Intron-binding protein aquarius N-terminus Nucleotid_trans PF03407.16 EKX36446.1 - 1e-09 38.7 0.0 1.3e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF948 PF06103.11 EKX36447.1 - 0.00096 19.4 0.0 0.34 11.2 0.0 2.8 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) DUF2964 PF11177.8 EKX36447.1 - 0.0016 18.6 11.2 10 6.4 0.8 4.8 1 1 1 2 2 2 2 Protein of unknown function (DUF2964) DUF4744 PF15918.5 EKX36447.1 - 0.003 18.4 0.0 9.3 7.2 0.0 3.0 1 1 3 4 4 4 2 Domain of unknown function (DUF4744) BROMI PF14961.6 EKX36447.1 - 0.065 10.6 0.1 3.3 5.0 0.0 1.9 1 1 1 2 2 2 0 Broad-minded protein Selenoprotein_S PF06936.11 EKX36448.1 - 0.03 14.2 0.0 0.072 12.9 0.0 1.7 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF3180 PF11377.8 EKX36448.1 - 0.12 12.5 0.2 2.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) TIG PF01833.24 EKX36449.1 - 4.7e-25 87.5 11.2 4.1e-11 42.8 0.6 4.1 4 0 0 4 4 4 3 IPT/TIG domain TIG PF01833.24 EKX36450.1 - 8.1e-33 112.4 43.7 6.8e-07 29.3 0.2 12.9 12 1 0 12 12 12 9 IPT/TIG domain XG_FTase PF03254.13 EKX36451.1 - 1e-07 31.0 0.0 1.1e-07 30.9 0.0 1.0 1 0 0 1 1 1 1 Xyloglucan fucosyltransferase Sortilin-Vps10 PF15902.5 EKX36452.1 - 3e-98 329.5 1.5 3.8e-98 329.2 1.5 1.1 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EKX36452.1 - 3.3e-41 141.5 0.6 5e-41 140.9 0.6 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 EKX36452.1 - 6e-05 22.5 17.8 0.69 10.1 0.1 7.3 7 0 0 7 7 7 3 BNR/Asp-box repeat BNR_6 PF15899.5 EKX36452.1 - 0.46 10.7 7.6 4.1 7.7 0.2 4.7 6 0 0 6 6 6 0 BNR-Asp box repeat AA_kinase PF00696.28 EKX36453.1 - 5.5e-35 121.1 2.2 7e-35 120.7 2.2 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 EKX36453.1 - 0.00044 20.1 0.0 0.0014 18.5 0.0 1.8 1 0 0 1 1 1 1 PUA domain UCH PF00443.29 EKX36454.1 - 9.1e-36 123.7 0.5 9.1e-36 123.7 0.5 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EKX36454.1 - 1.5e-15 57.6 0.2 1.5e-15 57.6 0.2 2.0 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Kinesin PF00225.23 EKX36455.1 - 8.8e-111 370.0 0.5 1e-110 369.8 0.5 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX36455.1 - 1.5e-24 86.6 0.2 3.5e-24 85.4 0.0 1.7 2 0 0 2 2 2 1 Microtubule binding LysR_substrate PF03466.20 EKX36455.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain ResIII PF04851.15 EKX36455.1 - 0.088 12.8 0.2 0.26 11.3 0.2 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CHCH PF06747.13 EKX36456.1 - 3.3e-07 30.3 4.6 4.3e-07 29.9 4.6 1.1 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 EKX36456.1 - 0.008 16.2 2.6 0.011 15.7 2.6 1.2 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 EKX36456.1 - 0.049 13.7 1.7 0.096 12.7 1.7 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF2076 PF09849.9 EKX36456.1 - 2.7 8.0 8.8 7.7 6.5 8.8 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) PTS-HPr PF00381.19 EKX36457.1 - 0.056 13.7 0.3 0.091 13.0 0.3 1.4 1 0 0 1 1 1 0 PTS HPr component phosphorylation site cNMP_binding PF00027.29 EKX36458.1 - 0.0018 18.3 0.0 0.0084 16.2 0.0 2.2 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain LRS4 PF10422.9 EKX36459.1 - 0.0094 15.5 0.3 0.014 15.0 0.3 1.2 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 Sec5 PF15469.6 EKX36459.1 - 0.02 14.7 1.4 0.025 14.4 1.4 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec5 Flagellin_C PF00700.21 EKX36459.1 - 0.046 14.1 1.4 0.057 13.8 0.2 1.7 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region Mg_trans_NIPA PF05653.14 EKX36461.1 - 4.5e-32 111.3 13.3 5.2e-32 111.1 13.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EKX36461.1 - 0.0032 17.6 2.9 0.0032 17.6 2.9 3.3 2 1 0 2 2 2 1 EamA-like transporter family DUF3185 PF11381.8 EKX36461.1 - 0.0079 16.2 1.4 0.032 14.2 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3185) TauE PF01925.19 EKX36461.1 - 0.12 11.9 0.1 0.12 11.9 0.1 2.2 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE CcmE PF03100.15 EKX36461.1 - 0.66 10.0 3.3 2.5 8.1 0.1 3.0 3 1 1 4 4 4 0 CcmE DUF2243 PF10002.9 EKX36461.1 - 0.73 9.9 5.8 6.3 6.9 0.4 2.7 2 1 1 3 3 3 0 Predicted membrane protein (DUF2243) MMPL PF03176.15 EKX36461.1 - 5.5 5.8 5.9 3.5 6.4 0.2 2.3 2 0 0 2 2 2 0 MMPL family Peptidase_A22B PF04258.13 EKX36461.1 - 6.1 6.3 11.8 4.2 6.8 0.6 2.2 2 0 0 2 2 2 0 Signal peptide peptidase Pkinase PF00069.25 EKX36462.1 - 4.4e-34 118.0 0.0 7.5e-33 114.0 0.0 2.6 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX36462.1 - 4.4e-12 45.8 0.0 7.5e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ZU5 PF00791.20 EKX36463.1 - 0.054 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 ZU5 domain DUF4483 PF14825.6 EKX36464.1 - 2.8e-30 105.2 0.1 3.6e-30 104.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) CWC25 PF12542.8 EKX36466.1 - 1.5e-14 54.7 5.7 1.5e-14 54.7 5.7 4.2 3 2 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 EKX36466.1 - 2.3e-10 40.5 16.7 2.3e-10 40.5 16.7 4.3 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR DHC_N1 PF08385.12 EKX36467.1 - 1e-162 542.7 13.5 1e-162 542.7 13.5 5.7 3 1 3 6 6 6 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 EKX36467.1 - 1.2e-156 520.8 0.0 1.1e-154 514.3 0.0 2.8 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EKX36467.1 - 2.1e-137 458.4 21.4 2.1e-137 458.4 21.4 5.0 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EKX36467.1 - 3.2e-104 347.9 0.0 3.2e-104 347.9 0.0 4.0 4 0 0 4 4 4 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EKX36467.1 - 1.1e-95 320.5 4.2 6.4e-95 317.9 0.0 3.7 4 0 0 4 4 4 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EKX36467.1 - 3.3e-87 291.2 1.6 3.3e-87 291.2 1.6 3.7 3 1 1 4 4 3 2 ATP-binding dynein motor region AAA_7 PF12775.7 EKX36467.1 - 1.8e-70 236.1 0.3 5.8e-67 224.7 0.0 3.8 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EKX36467.1 - 5.1e-58 195.5 0.3 1.9e-57 193.6 0.3 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 EKX36467.1 - 3.9e-51 174.1 9.9 3.9e-51 174.1 9.9 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EKX36467.1 - 1.5e-41 141.2 0.0 1.1e-38 132.0 0.0 4.0 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 EKX36467.1 - 2.6e-29 102.0 0.0 2.4e-13 50.3 0.0 5.6 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 EKX36467.1 - 1.3e-27 96.4 0.1 1.3e-26 93.2 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EKX36467.1 - 2.9e-16 59.5 1.1 2.4e-15 56.5 0.1 3.3 3 0 0 3 3 1 1 AAA+ lid domain AAA PF00004.29 EKX36467.1 - 1.2e-11 45.2 0.5 0.00026 21.4 0.0 4.9 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EKX36467.1 - 1.4e-07 32.1 0.1 0.028 15.0 0.0 4.8 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 EKX36467.1 - 3.2e-06 27.4 0.7 0.027 14.7 0.0 4.9 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.6 EKX36467.1 - 1.5e-05 25.5 6.2 0.018 15.5 0.0 5.9 6 1 0 7 7 4 1 AAA ATPase domain AAA_14 PF13173.6 EKX36467.1 - 1.6e-05 24.9 0.4 0.00025 21.1 0.0 3.3 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 EKX36467.1 - 0.00017 21.5 0.1 0.01 15.8 0.0 3.4 2 0 0 2 2 2 1 Rad17 P-loop domain T2SSE PF00437.20 EKX36467.1 - 0.00034 19.8 0.4 0.006 15.7 0.0 2.7 2 0 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.22 EKX36467.1 - 0.00062 20.1 0.1 2.3 8.6 0.0 4.3 3 0 0 3 3 3 1 RNA helicase AAA_30 PF13604.6 EKX36467.1 - 0.0014 18.4 0.7 2.4 7.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 EKX36467.1 - 0.0031 17.8 0.1 0.23 11.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 EKX36467.1 - 0.0038 16.6 0.0 1.3 8.4 0.0 2.9 2 0 0 2 2 2 1 Bacterial TniB protein NTPase_1 PF03266.15 EKX36467.1 - 0.0063 16.4 0.0 0.078 12.9 0.0 3.1 1 0 0 1 1 1 1 NTPase Csa1 PF06023.12 EKX36467.1 - 0.0078 15.6 0.7 0.024 14.0 0.7 1.8 1 0 0 1 1 1 1 CRISPR-associated exonuclease Csa1 AAA_21 PF13304.6 EKX36467.1 - 0.011 15.6 0.0 0.93 9.2 0.1 2.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 EKX36467.1 - 0.034 14.3 0.1 6.9 6.8 0.0 3.8 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 EKX36467.1 - 0.041 13.5 0.0 0.15 11.7 0.0 2.0 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Viral_helicase1 PF01443.18 EKX36467.1 - 0.044 13.5 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 EKX36467.1 - 0.045 13.1 0.0 0.35 10.2 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.9 EKX36467.1 - 0.069 12.9 0.2 7.2 6.4 0.0 3.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 EKX36467.1 - 0.1 12.3 0.1 3.4 7.5 0.0 3.1 3 0 0 3 3 3 0 P-loop containing region of AAA domain EELM2 PF15863.5 EKX36467.1 - 0.13 12.4 0.7 0.37 10.9 0.0 2.2 2 0 0 2 2 1 0 Extended EGL-27 and MTA1 homology domain PhoU PF01895.19 EKX36467.1 - 0.17 12.4 3.5 11 6.6 0.5 5.3 4 0 0 4 4 3 0 PhoU domain ABC_tran PF00005.27 EKX36467.1 - 0.53 10.8 6.9 0.73 10.3 0.0 3.9 3 0 0 3 3 2 0 ABC transporter TPR_12 PF13424.6 EKX36468.1 - 1.1e-05 25.6 4.1 0.00019 21.6 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF2491 PF10679.9 EKX36468.1 - 0.001 18.3 0.4 0.0031 16.7 0.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2491) Pkinase PF00069.25 EKX36469.1 - 2.1e-56 191.2 0.0 2.5e-56 191.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX36469.1 - 3.4e-42 144.5 0.0 3.8e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX36469.1 - 3e-06 26.3 0.0 4.8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EKX36469.1 - 0.0016 17.8 0.0 0.004 16.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EKX36469.1 - 0.0055 16.1 0.0 0.0083 15.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EKX36469.1 - 0.05 13.2 0.1 2.5 7.7 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Hist_deacetyl PF00850.19 EKX36470.1 - 7.9e-84 281.7 0.0 8.9e-84 281.6 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain CAP_GLY PF01302.25 EKX36471.1 - 2.4e-16 59.5 0.7 3e-16 59.2 0.7 1.1 1 0 0 1 1 1 1 CAP-Gly domain EF-hand_1 PF00036.32 EKX36473.1 - 1.1e-12 46.5 0.2 3.4e-06 26.2 0.0 2.1 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX36473.1 - 1.4e-10 41.5 0.1 1.6e-10 41.3 0.1 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX36473.1 - 1.9e-10 39.7 0.1 0.00017 20.9 0.0 2.1 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX36473.1 - 8.2e-10 38.4 3.1 5.7e-07 29.3 0.5 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX36473.1 - 1.3e-08 34.1 0.0 8.9e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain CCD48 PF15799.5 EKX36473.1 - 0.0082 14.5 0.0 0.0085 14.5 0.0 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 SPARC_Ca_bdg PF10591.9 EKX36473.1 - 0.0083 16.4 0.0 0.0088 16.3 0.0 1.0 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EKX36473.1 - 0.024 14.6 0.2 0.33 10.9 0.1 1.9 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Kinase-PolyVal PF18762.1 EKX36473.1 - 0.086 12.8 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins 60KD_IMP PF02096.20 EKX36474.1 - 5.2e-26 91.5 2.8 6.4e-26 91.2 2.8 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein DUF2779 PF11074.8 EKX36477.1 - 9.2e-05 22.9 0.0 0.00018 22.0 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function(DUF2779) DNA_pol_A_exo1 PF01612.20 EKX36477.1 - 0.00045 20.0 0.3 0.00045 20.0 0.3 1.3 1 1 0 1 1 1 1 3'-5' exonuclease DNA_pol_E_B PF04042.16 EKX36479.1 - 6.2e-42 143.3 0.1 1e-41 142.6 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Zip PF02535.22 EKX36480.1 - 0.019 14.2 0.5 0.019 14.2 0.5 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter DUF812 PF05667.11 EKX36480.1 - 0.02 13.8 27.5 0.019 13.9 9.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DUF4745 PF15923.5 EKX36480.1 - 0.027 14.5 0.1 0.079 12.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4745) Plasmodium_Vir PF05795.11 EKX36480.1 - 0.049 13.1 1.4 0.37 10.2 0.0 2.3 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Spc7 PF08317.11 EKX36480.1 - 0.11 11.4 32.8 0.016 14.1 13.6 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein Connexin PF00029.19 EKX36480.1 - 0.21 11.3 0.7 0.94 9.2 0.7 2.1 1 0 0 1 1 1 0 Connexin LtuB PF17455.2 EKX36480.1 - 0.32 11.6 1.7 5.6 7.6 0.1 3.2 4 0 0 4 4 4 0 Late transcription unit B ATG_C PF09333.11 EKX36480.1 - 0.5 10.7 3.9 0.4 11.0 0.2 2.8 3 1 0 3 3 3 0 Autophagy-related protein C terminal domain DUF1664 PF07889.12 EKX36480.1 - 1.8 8.6 18.6 2.1 8.4 0.8 4.2 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) Ribosomal_L29 PF00831.23 EKX36480.1 - 5.2 7.1 15.8 0.5 10.4 0.2 5.6 6 1 0 6 6 6 0 Ribosomal L29 protein THOC7 PF05615.13 EKX36480.1 - 5.2 7.4 33.3 0.081 13.2 2.1 4.2 2 2 1 3 3 3 0 Tho complex subunit 7 COG2 PF06148.11 EKX36480.1 - 6.4 6.9 19.9 2.4 8.3 0.6 4.7 2 2 3 6 6 6 0 COG (conserved oligomeric Golgi) complex component, COG2 CAF1 PF04857.20 EKX36481.1 - 3e-21 75.9 0.3 2.3e-11 43.5 0.0 2.6 2 1 0 2 2 2 2 CAF1 family ribonuclease SAM_2 PF07647.17 EKX36483.1 - 1.1e-17 63.9 0.1 1.4e-17 63.6 0.1 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EKX36483.1 - 1.4e-17 63.9 0.1 1.7e-17 63.6 0.1 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 EKX36483.1 - 0.0087 16.3 0.1 0.016 15.4 0.1 1.4 1 1 0 1 1 1 1 Ste50p, sterile alpha motif SAM_PNT PF02198.16 EKX36483.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.5 1 1 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain PH PF00169.29 EKX36484.1 - 0.00032 21.2 0.0 0.00087 19.8 0.0 1.8 1 0 0 1 1 1 1 PH domain Ion_trans PF00520.31 EKX36484.1 - 0.014 14.7 1.2 0.29 10.3 0.1 2.3 2 0 0 2 2 2 0 Ion transport protein Dmrt1 PF12374.8 EKX36484.1 - 0.44 11.0 0.1 0.44 11.0 0.1 3.3 3 0 0 3 3 3 0 Double-sex mab3 related transcription factor 1 Pkinase PF00069.25 EKX36485.1 - 6.6e-38 130.6 0.1 7.2e-38 130.5 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX36485.1 - 5.8e-26 91.3 0.1 6.4e-26 91.2 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX36485.1 - 0.00013 20.9 0.0 0.00021 20.2 0.0 1.3 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 EKX36485.1 - 0.0084 15.7 0.1 0.01 15.5 0.1 1.1 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EKX36485.1 - 0.0086 15.4 0.0 0.0088 15.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EKX36485.1 - 0.014 14.7 0.2 0.018 14.4 0.2 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EKX36485.1 - 0.065 12.7 0.1 0.095 12.2 0.0 1.3 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 EKX36485.1 - 0.15 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family KilA-N PF04383.13 EKX36487.1 - 0.028 14.3 0.7 0.054 13.3 0.5 1.7 1 1 0 1 1 1 0 KilA-N domain Golgin_A5 PF09787.9 EKX36487.1 - 0.073 12.5 7.0 0.097 12.1 7.0 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Myc_N PF01056.18 EKX36488.1 - 0.0091 15.9 2.2 0.0091 15.9 2.2 2.0 2 0 0 2 2 2 1 Myc amino-terminal region GAS PF13851.6 EKX36488.1 - 0.016 14.6 28.0 0.19 11.1 10.6 3.9 1 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EKX36488.1 - 0.063 12.2 27.0 0.24 10.2 11.8 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein AAA_24 PF13479.6 EKX36488.1 - 0.077 12.7 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain BLOC1_2 PF10046.9 EKX36488.1 - 0.51 10.7 16.5 4.1 7.8 1.4 3.9 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RsbU_N PF08673.10 EKX36488.1 - 2.1 8.5 8.4 1.4 9.1 0.5 3.5 3 1 1 4 4 4 0 Phosphoserine phosphatase RsbU, N-terminal domain Baculo_PEP_C PF04513.12 EKX36488.1 - 2.1 8.4 5.5 2.9 7.9 2.0 2.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GIT1_C PF12205.8 EKX36488.1 - 5.3 7.2 12.9 1.7 8.8 0.9 3.3 2 1 1 4 4 4 0 G protein-coupled receptor kinase-interacting protein 1 C term ZapD PF07072.11 EKX36490.1 - 0.091 12.5 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Cell division protein Transglut_core PF01841.19 EKX36491.1 - 8.7e-10 39.0 0.1 2.2e-09 37.7 0.1 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF5314 PF17241.2 EKX36491.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5314) PLAT PF01477.23 EKX36492.1 - 5.1e-12 46.4 0.0 1e-11 45.4 0.0 1.5 1 0 0 1 1 1 1 PLAT/LH2 domain SAM_1 PF00536.30 EKX36492.1 - 2.6e-05 24.5 0.1 6.2e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EKX36492.1 - 3.1e-05 24.0 0.1 8.3e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NTS PF15447.6 EKX36492.1 - 0.041 14.4 0.1 0.15 12.6 0.1 1.9 1 0 0 1 1 1 0 N-terminal segments of PfEMP1 EF-hand_7 PF13499.6 EKX36492.1 - 0.12 12.9 0.0 0.36 11.3 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 EKX36492.1 - 0.18 11.4 0.0 3.3 7.5 0.0 2.7 2 0 0 2 2 2 0 EF hand SOGA PF11365.8 EKX36492.1 - 0.72 11.0 8.0 3.2 8.9 3.6 2.9 2 0 0 2 2 2 0 Protein SOGA DUF3776 PF12618.8 EKX36493.1 - 0.048 14.2 0.1 0.061 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3776) Pkinase PF00069.25 EKX36494.1 - 1e-57 195.6 0.1 4.9e-56 190.0 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX36494.1 - 4.2e-28 98.3 0.0 5.3e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX36494.1 - 0.00014 21.3 0.0 0.00025 20.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EKX36494.1 - 0.0018 17.3 0.0 0.0034 16.4 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Arc_PepC PF06819.11 EKX36494.1 - 0.17 12.0 0.2 1.7 8.8 0.2 2.1 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminal Domain AKAP95 PF04988.12 EKX36495.1 - 0.0043 17.3 0.2 0.0079 16.4 0.2 1.4 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) DegT_DnrJ_EryC1 PF01041.17 EKX36495.1 - 0.017 14.5 0.6 0.023 14.0 0.6 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family F-box PF00646.33 EKX36495.1 - 0.28 11.1 1.7 0.8 9.7 1.7 1.7 1 0 0 1 1 1 0 F-box domain DUF4410 PF14366.6 EKX36495.1 - 3.6 7.5 4.6 7.8 6.4 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4410) UEV PF05743.13 EKX36496.1 - 5.2e-22 78.0 0.2 9.7e-22 77.1 0.2 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 EKX36496.1 - 8e-19 67.4 3.1 1.1e-18 66.9 1.0 2.1 1 1 1 2 2 2 1 Vps23 core domain UQ_con PF00179.26 EKX36496.1 - 0.00022 20.9 0.1 0.00057 19.6 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SbsC_C PF18058.1 EKX36496.1 - 0.032 14.5 1.2 0.069 13.4 1.2 1.6 1 0 0 1 1 1 0 SbsC C-terminal domain Ino80_Iec3 PF14612.6 EKX36496.1 - 0.035 14.8 7.1 0.04 14.6 6.3 1.5 1 1 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling PDZ_6 PF17820.1 EKX36497.1 - 1.6e-06 27.9 0.0 1.5e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX36497.1 - 0.00046 20.5 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX36497.1 - 0.014 15.7 0.0 0.031 14.6 0.0 1.5 1 0 0 1 1 1 0 PDZ domain FoP_duplication PF13865.6 EKX36497.1 - 4.2 8.0 12.1 12 6.5 12.1 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 ANF_receptor PF01094.28 EKX36498.1 - 4.9e-85 285.7 3.0 7.1e-46 156.9 0.1 2.2 2 0 0 2 2 2 2 Receptor family ligand binding region Peripla_BP_6 PF13458.6 EKX36498.1 - 1.1e-18 68.0 0.8 3.4e-08 33.5 0.5 3.1 3 0 0 3 3 3 2 Periplasmic binding protein Chordopox_E11 PF06138.12 EKX36498.1 - 0.032 14.6 0.0 0.077 13.3 0.0 1.6 1 0 0 1 1 1 0 Chordopoxvirus E11 protein STT3 PF02516.14 EKX36499.1 - 1.5e-64 218.7 23.9 3.1e-63 214.4 23.9 2.0 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Uds1 PF15456.6 EKX36500.1 - 0.019 15.2 3.8 0.84 9.8 0.2 2.4 2 0 0 2 2 2 0 Up-regulated During Septation Csm1_N PF18504.1 EKX36500.1 - 0.13 12.6 1.2 3.9 7.9 0.1 2.5 2 0 0 2 2 2 0 Csm1 N-terminal domain ABC_tran_CTD PF16326.5 EKX36500.1 - 0.38 11.0 5.1 7.5 6.9 0.9 2.5 2 1 0 2 2 2 0 ABC transporter C-terminal domain Endonuclease_NS PF01223.23 EKX36501.1 - 6.4e-41 140.6 0.0 7.1e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease TB2_DP1_HVA22 PF03134.19 EKX36502.1 - 3.8e-16 58.8 1.5 1.7e-14 53.5 1.4 2.2 2 0 0 2 2 2 2 TB2/DP1, HVA22 family OTCace PF00185.24 EKX36503.1 - 6.8e-49 166.0 0.0 1.1e-48 165.3 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 EKX36503.1 - 2.9e-41 140.9 0.1 4.5e-41 140.3 0.1 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Rhomboid PF01694.22 EKX36504.1 - 0.0046 17.0 0.5 0.0087 16.1 0.5 1.4 1 0 0 1 1 1 1 Rhomboid family Thioredoxin PF00085.20 EKX36505.1 - 3.5e-27 94.4 0.0 3.4e-23 81.6 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 EKX36505.1 - 8e-07 28.7 0.0 1.1e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EKX36505.1 - 4.9e-06 26.8 0.0 1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 EKX36505.1 - 5.5e-06 26.5 0.2 1.8e-05 24.8 0.1 1.9 2 1 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 EKX36505.1 - 5.2e-05 23.0 0.0 8.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 EKX36505.1 - 5.7e-05 23.5 0.0 0.00044 20.7 0.1 2.3 2 1 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 EKX36505.1 - 9.7e-05 22.3 0.0 0.00019 21.4 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Glutaredoxin PF00462.24 EKX36505.1 - 0.0012 19.0 0.1 0.0032 17.7 0.1 1.7 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.6 EKX36505.1 - 0.002 17.9 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 EKX36505.1 - 0.011 14.7 0.0 0.14 11.1 0.0 2.0 1 1 1 2 2 2 0 Phosducin NifZ PF04319.13 EKX36505.1 - 0.029 14.2 0.1 0.17 11.7 0.0 2.2 1 1 1 2 2 2 0 NifZ domain TraF PF13728.6 EKX36505.1 - 0.043 13.6 0.0 0.098 12.5 0.0 1.5 2 0 0 2 2 2 0 F plasmid transfer operon protein DIM1 PF02966.16 EKX36505.1 - 0.045 13.5 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 Mitosis protein DIM1 DarA_N PF18788.1 EKX36506.1 - 0.00014 21.9 0.1 0.00021 21.4 0.1 1.4 1 1 0 1 1 1 1 Defence against restriction A N-terminal YqgC PF17430.2 EKX36507.1 - 0.051 13.7 2.7 0.16 12.1 2.7 1.9 1 0 0 1 1 1 0 Uncharacterized YqgC-like Uds1 PF15456.6 EKX36507.1 - 0.17 12.0 0.1 0.17 12.0 0.1 2.0 2 0 0 2 2 2 0 Up-regulated During Septation DUF913 PF06025.12 EKX36507.1 - 0.55 9.2 2.5 0.3 10.0 0.3 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) HNOBA PF07701.14 EKX36509.1 - 0.052 13.0 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Heme NO binding associated DUF1079 PF06435.11 EKX36509.1 - 0.16 12.2 5.9 8.8 6.7 0.4 3.5 2 1 1 3 3 3 0 Repeat of unknown function (DUF1079) Fib_alpha PF08702.10 EKX36509.1 - 0.43 10.8 2.0 1.1 9.5 1.3 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family RVT_1 PF00078.27 EKX36510.1 - 0.042 13.4 0.0 1.4 8.4 0.0 2.4 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) K-box PF01486.17 EKX36510.1 - 1.2 9.4 3.7 9.8 6.4 1.9 2.3 2 0 0 2 2 2 0 K-box region LRR_6 PF13516.6 EKX36511.1 - 2.1e-25 86.6 33.7 0.0017 18.3 0.2 11.1 10 1 1 11 11 11 9 Leucine Rich repeat LRR_4 PF12799.7 EKX36511.1 - 0.00077 19.8 30.2 2.9 8.4 0.2 7.2 5 3 3 8 8 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX36511.1 - 0.006 17.0 15.8 10 7.1 0.1 7.5 7 1 0 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.6 EKX36511.1 - 0.058 13.2 29.0 0.2 11.5 0.4 8.1 5 3 1 7 7 7 0 Leucine rich repeat BSP_II PF05432.11 EKX36512.1 - 0.0016 18.2 16.4 0.0021 17.8 16.4 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) SDA1 PF05285.12 EKX36512.1 - 0.16 11.3 30.7 0.23 10.9 30.7 1.1 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 EKX36512.1 - 0.44 9.3 9.2 0.47 9.2 9.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 EKX36512.1 - 0.45 9.8 25.5 0.52 9.6 25.5 1.1 1 0 0 1 1 1 0 BUD22 Drc1-Sld2 PF11719.8 EKX36512.1 - 1.1 8.7 17.0 1.4 8.4 17.0 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein DUF4746 PF15928.5 EKX36512.1 - 1.6 8.0 9.8 2.3 7.6 9.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop14 PF04147.12 EKX36512.1 - 2.1 6.5 31.2 2.8 6.1 31.2 1.1 1 0 0 1 1 1 0 Nop14-like family NPR3 PF03666.13 EKX36512.1 - 3.7 6.2 8.8 4.7 5.9 8.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TFIIF_alpha PF05793.12 EKX36512.1 - 3.7 6.0 27.3 4.4 5.8 27.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-CHCC PF10276.9 EKX36513.1 - 5.2e-15 55.2 1.7 5.2e-15 55.2 1.7 1.6 2 0 0 2 2 2 1 Zinc-finger domain zf_C2H2_6 PF18450.1 EKX36513.1 - 0.054 13.2 0.8 0.054 13.2 0.8 1.9 2 0 0 2 2 2 0 Zinc Finger domain Abhydrolase_6 PF12697.7 EKX36514.1 - 8.8e-20 72.2 0.4 1.1e-19 72.0 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EKX36514.1 - 4.2e-17 62.2 0.0 5.5e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EKX36514.1 - 1.2e-16 61.1 0.1 6e-10 39.2 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold UPF0227 PF05728.12 EKX36514.1 - 0.00025 21.0 0.0 0.0067 16.4 0.0 2.6 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0227) Esterase PF00756.20 EKX36514.1 - 0.019 14.7 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.20 EKX36514.1 - 0.027 14.6 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 EKX36514.1 - 0.038 13.8 0.0 5.2 6.8 0.0 2.4 3 0 0 3 3 3 0 Alpha/beta hydrolase family Palm_thioest PF02089.15 EKX36514.1 - 0.072 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase QSregVF_b PF12843.7 EKX36514.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor DBI_PRT PF02277.17 EKX36515.1 - 5.9e-87 292.0 13.0 8.3e-87 291.5 13.0 1.1 1 0 0 1 1 1 1 Phosphoribosyltransferase Baculo_p74_N PF08404.10 EKX36516.1 - 0.04 13.0 0.1 0.058 12.5 0.1 1.2 1 0 0 1 1 1 0 Baculoviridae P74 N-terminal ORC3_N PF07034.11 EKX36517.1 - 9e-12 44.7 0.5 8.7e-11 41.5 0.0 2.1 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus Thymidylate_kin PF02223.17 EKX36517.1 - 0.096 12.4 1.2 8.9 5.9 0.0 2.8 3 0 0 3 3 3 0 Thymidylate kinase Pkinase PF00069.25 EKX36518.1 - 4.5e-30 104.9 0.0 6.4e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX36518.1 - 1.7e-17 63.6 0.0 2.2e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 EKX36518.1 - 1.4e-05 25.6 0.2 3.1e-05 24.4 0.2 1.5 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 EKX36518.1 - 0.0063 16.9 0.1 0.018 15.4 0.1 1.8 1 1 0 1 1 1 1 Pleckstrin homology domain GST_C PF00043.25 EKX36519.1 - 8.9e-05 22.6 0.0 0.00022 21.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EKX36519.1 - 0.0076 16.3 0.8 0.025 14.6 0.8 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EKX36519.1 - 0.02 15.1 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DSPc PF00782.20 EKX36520.1 - 6.9e-20 71.2 0.1 9.9e-20 70.7 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EKX36520.1 - 2.3e-06 27.8 0.0 3.1e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 EKX36520.1 - 0.0079 15.8 0.2 0.013 15.1 0.2 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Ribosomal_S27 PF01599.19 EKX36524.1 - 0.086 13.0 1.3 0.31 11.2 0.2 2.2 2 0 0 2 2 2 0 Ribosomal protein S27a DUF4813 PF16072.5 EKX36525.1 - 0.074 12.7 0.3 0.13 11.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) DUF966 PF06136.13 EKX36525.1 - 2.8 7.6 33.7 0.17 11.6 12.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Macoilin PF09726.9 EKX36525.1 - 6.5 5.2 35.2 4.1 5.9 20.2 2.2 2 0 0 2 2 2 0 Macoilin family Importin_rep_4 PF18808.1 EKX36526.1 - 1.5e-14 54.0 0.5 1.5e-14 54.0 0.5 3.1 3 0 0 3 3 2 1 Importin repeat DRIM PF07539.12 EKX36526.1 - 1e-07 30.7 8.6 0.0014 17.1 0.2 3.7 3 1 0 3 3 3 3 Down-regulated in metastasis RIX1 PF08167.12 EKX36526.1 - 2.7e-06 27.3 8.3 0.0042 16.9 0.1 4.8 4 1 1 5 5 5 2 rRNA processing/ribosome biogenesis DUF3385 PF11865.8 EKX36526.1 - 5.1e-06 26.5 3.9 0.011 15.7 0.0 5.0 3 1 2 5 5 5 1 Domain of unknown function (DUF3385) HEAT_EZ PF13513.6 EKX36526.1 - 3.7e-05 24.1 17.5 0.082 13.4 0.1 7.9 8 1 1 9 9 8 2 HEAT-like repeat Tti2 PF10521.9 EKX36526.1 - 5.9e-05 22.7 2.6 9.9 5.6 0.0 5.4 5 1 0 6 6 6 2 Tti2 family IBN_N PF03810.19 EKX36526.1 - 0.00011 22.1 0.0 0.001 18.9 0.0 2.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 EKX36526.1 - 0.00028 21.2 9.9 0.31 11.4 0.1 6.4 7 1 1 8 8 6 3 HEAT repeats MMS19_C PF12460.8 EKX36526.1 - 0.0003 20.1 19.3 0.03 13.4 0.4 6.9 4 3 3 7 7 7 3 RNAPII transcription regulator C-terminal HEAT PF02985.22 EKX36526.1 - 0.0034 17.5 35.4 0.0075 16.4 0.1 10.1 11 0 0 11 11 11 1 HEAT repeat ParcG PF10274.9 EKX36526.1 - 0.0038 17.4 3.3 3 7.9 0.0 5.0 3 1 1 6 6 6 1 Parkin co-regulated protein V-ATPase_H_N PF03224.14 EKX36526.1 - 0.02 14.2 6.2 0.37 10.0 0.1 3.8 3 1 1 4 4 4 0 V-ATPase subunit H CLASP_N PF12348.8 EKX36526.1 - 0.033 13.8 4.6 1.1 8.7 0.0 4.3 3 2 1 5 5 5 0 CLASP N terminal Cnd1 PF12717.7 EKX36526.1 - 0.049 13.7 0.6 7.7 6.5 0.0 3.8 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EKX36526.1 - 0.061 13.9 0.1 1.4e+02 3.1 0.0 4.9 4 1 1 5 5 5 0 Vacuolar 14 Fab1-binding region Importin_rep_5 PF18816.1 EKX36526.1 - 0.17 12.2 0.3 1.4 9.3 0.1 2.7 2 0 0 2 2 2 0 Importin repeat TPR_1 PF00515.28 EKX36527.1 - 4.6e-10 38.9 5.7 0.00023 20.9 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX36527.1 - 7.8e-06 25.6 11.2 0.014 15.4 0.0 4.6 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX36527.1 - 7.2e-05 22.4 1.1 0.0032 17.1 0.0 3.0 2 1 0 2 2 2 1 TPR repeat ANAPC3 PF12895.7 EKX36527.1 - 0.0041 17.3 0.9 0.0041 17.3 0.9 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EKX36527.1 - 0.015 15.7 1.8 3.6 8.2 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX36527.1 - 0.054 13.8 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX36527.1 - 0.31 11.6 4.0 11 6.6 0.4 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX36527.1 - 0.36 11.8 2.3 33 5.7 0.0 3.8 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX36527.1 - 0.44 10.9 3.3 13 6.3 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat EIIBC-GUT_N PF03612.14 EKX36527.1 - 6.9 6.4 6.4 1.7 8.4 0.7 2.0 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus B-block_TFIIIC PF04182.12 EKX36529.1 - 5.1e-13 49.0 0.1 5.6e-12 45.7 0.0 2.4 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC T4SS_CagC PF16943.5 EKX36529.1 - 0.03 14.5 0.0 0.4 10.9 0.0 2.3 2 0 0 2 2 2 0 Cag pathogenicity island, type IV secretory system MSC PF09402.10 EKX36529.1 - 0.032 13.7 1.3 0.059 12.8 0.1 1.9 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain CheR_N PF03705.15 EKX36529.1 - 0.066 12.9 0.3 0.18 11.6 0.3 1.7 1 0 0 1 1 1 0 CheR methyltransferase, all-alpha domain YvrJ PF12841.7 EKX36531.1 - 0.015 14.8 0.1 0.026 14.1 0.1 1.4 1 0 0 1 1 1 0 YvrJ protein family MHC2-interact PF09307.10 EKX36531.1 - 0.04 13.9 0.3 0.084 12.9 0.3 1.5 1 0 0 1 1 1 0 CLIP, MHC2 interacting LapA_dom PF06305.11 EKX36531.1 - 0.32 10.8 0.9 0.55 10.1 0.9 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Zn_clus PF00172.18 EKX36532.1 - 7.8e-06 25.9 25.2 1.4e-05 25.1 17.0 3.9 3 1 1 4 4 4 3 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C3HC4_2 PF13923.6 EKX36533.1 - 1.1e-10 41.2 10.8 1.4e-10 40.8 10.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX36533.1 - 5.4e-10 39.0 11.4 7.2e-10 38.6 11.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EKX36533.1 - 5.6e-09 35.7 10.1 6.9e-09 35.4 10.1 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX36533.1 - 6.1e-08 32.9 11.2 8.1e-08 32.5 11.2 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EKX36533.1 - 5.1e-05 23.2 10.4 8e-05 22.5 10.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EKX36533.1 - 7e-05 22.8 10.4 0.00012 22.0 10.4 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EKX36533.1 - 0.00038 20.5 9.9 0.00068 19.7 9.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EKX36533.1 - 0.0014 18.4 8.2 0.0031 17.2 8.2 1.6 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EKX36533.1 - 0.0015 18.8 8.0 0.0036 17.5 8.0 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_5 PF17121.5 EKX36533.1 - 0.0016 18.3 6.2 0.0064 16.4 6.2 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX36533.1 - 0.0023 17.7 7.6 0.02 14.7 7.6 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 TackOD1 PF18551.1 EKX36533.1 - 0.0074 16.0 5.7 0.0081 15.8 5.6 1.2 1 1 0 1 1 1 1 Thaumarchaeal output domain 1 zf-UDP PF14569.6 EKX36533.1 - 0.018 15.1 5.1 0.031 14.4 5.1 1.5 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RING_6 PF14835.6 EKX36533.1 - 0.024 14.5 1.8 0.027 14.4 1.8 1.2 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DZR PF12773.7 EKX36533.1 - 0.029 14.4 4.8 0.18 11.9 4.8 2.0 1 1 0 1 1 1 0 Double zinc ribbon zinc_ribbon_11 PF11682.8 EKX36533.1 - 0.057 13.4 1.4 0.058 13.4 0.5 1.4 2 0 0 2 2 2 0 Probable zinc-ribbon DUF1272 PF06906.11 EKX36533.1 - 0.1 12.7 4.0 0.15 12.2 4.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) zf-ANAPC11 PF12861.7 EKX36533.1 - 0.11 12.5 3.5 0.15 12.1 3.5 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 EKX36533.1 - 0.16 12.1 6.3 0.18 11.9 6.2 1.3 1 1 0 1 1 1 0 zinc RING finger of MSL2 zf-Nse PF11789.8 EKX36533.1 - 0.18 11.6 8.0 0.27 11.1 8.0 1.2 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 EKX36533.1 - 0.24 11.7 6.7 0.44 10.9 6.7 1.5 1 1 0 1 1 1 0 RING-like domain zf-RING_11 PF17123.5 EKX36533.1 - 3.2 7.6 9.7 8.3 6.3 9.7 1.8 1 0 0 1 1 1 0 RING-like zinc finger Pkinase PF00069.25 EKX36534.1 - 3.7e-62 210.1 0.0 4.3e-62 209.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX36534.1 - 7.2e-32 110.7 0.0 8.7e-32 110.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX36534.1 - 3.9e-06 26.4 0.0 6.3e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EKX36534.1 - 0.00053 19.4 0.0 0.0014 18.0 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Melibiase PF02065.18 EKX36535.1 - 3.7e-142 473.4 0.0 5e-142 473.0 0.0 1.2 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 EKX36535.1 - 1.2e-65 221.6 0.0 1.9e-63 214.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 EKX36535.1 - 5e-13 49.4 0.0 1.4e-10 41.5 0.0 2.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 36 C-terminal domain Glyco_hydro_31 PF01055.26 EKX36535.1 - 3.6e-07 29.8 0.0 5.6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Melibiase_2 PF16499.5 EKX36535.1 - 0.00051 19.3 0.0 0.0009 18.5 0.0 1.3 1 0 0 1 1 1 1 Alpha galactosidase A RWP-RK PF02042.15 EKX36536.1 - 6.3e-14 51.7 0.1 1.4e-13 50.6 0.1 1.6 1 0 0 1 1 1 1 RWP-RK domain Med3 PF11593.8 EKX36536.1 - 1.8 7.6 13.4 3.6 6.7 13.4 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal SKA2 PF16740.5 EKX36536.1 - 2.7 7.8 9.4 4.7 7.0 2.9 2.6 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 DivIC PF04977.15 EKX36536.1 - 6.9 6.5 7.4 2.9 7.7 4.6 1.8 2 0 0 2 2 2 0 Septum formation initiator La PF05383.17 EKX36537.1 - 1.4e-21 76.3 0.0 1.7e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 La domain Nuc_N PF14448.6 EKX36537.1 - 0.023 14.5 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 Nuclease N terminal FA_desaturase PF00487.24 EKX36538.1 - 3.8e-21 76.1 24.6 3.8e-21 76.1 24.6 1.5 1 1 1 2 2 2 1 Fatty acid desaturase FtsK_4TM PF13491.6 EKX36539.1 - 0.0047 16.6 2.4 0.087 12.5 1.9 2.0 1 1 1 2 2 2 2 4TM region of DNA translocase FtsK/SpoIIIE PrgI PF12666.7 EKX36539.1 - 0.084 13.6 0.1 0.14 12.8 0.1 1.3 1 0 0 1 1 1 0 PrgI family protein RelB_N PF18506.1 EKX36540.1 - 0.027 14.3 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 RelB Antitoxin alpha helical domain DUF3551 PF12071.8 EKX36541.1 - 0.0069 16.4 0.6 0.012 15.6 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3551) ORF6C PF10552.9 EKX36542.1 - 0.0032 17.5 1.4 0.0054 16.8 1.4 1.3 1 0 0 1 1 1 1 ORF6C domain FAM184 PF15665.5 EKX36543.1 - 1.7e-31 109.7 38.4 1.7e-31 109.7 38.4 9.8 1 1 7 9 9 9 2 Family with sequence similarity 184, A and B Mitofilin PF09731.9 EKX36543.1 - 0.00021 20.3 27.1 0.00021 20.3 27.1 6.3 1 1 6 7 7 7 1 Mitochondrial inner membrane protein TPR_MLP1_2 PF07926.12 EKX36543.1 - 0.0056 16.7 10.9 0.0056 16.7 10.9 13.7 1 1 10 13 13 13 3 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.12 EKX36543.1 - 0.021 14.9 51.4 0.48 10.5 1.1 10.9 5 3 2 8 8 8 0 Baculovirus polyhedron envelope protein, PEP, C terminus Osmo_CC PF08946.10 EKX36543.1 - 0.031 14.5 0.3 0.031 14.5 0.3 10.3 11 3 1 12 12 12 0 Osmosensory transporter coiled coil Spore_YhaL PF14147.6 EKX36543.1 - 1.6 8.5 9.6 2.9 7.7 5.0 4.3 2 0 0 2 2 2 0 Sporulation protein YhaL DUF3437 PF11919.8 EKX36543.1 - 9.6 6.2 6.8 49 3.9 0.5 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) Myb_DNA-binding PF00249.31 EKX36545.1 - 7.7e-05 22.8 0.1 0.00019 21.5 0.1 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain CLASP_N PF12348.8 EKX36546.1 - 6.1e-23 81.6 0.8 1.4e-22 80.4 0.3 1.9 2 1 0 2 2 2 1 CLASP N terminal Tropomyosin_1 PF12718.7 EKX36546.1 - 0.0057 16.8 5.2 0.0057 16.8 5.2 2.9 2 1 1 3 3 3 1 Tropomyosin like SOGA PF11365.8 EKX36546.1 - 0.011 16.8 6.7 0.011 16.8 6.7 3.0 2 1 0 2 2 2 0 Protein SOGA IFP_35_N PF07334.13 EKX36546.1 - 0.026 14.6 0.2 0.079 13.0 0.2 1.9 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus APC_N_CC PF16689.5 EKX36546.1 - 0.036 14.1 0.4 0.15 12.1 0.4 2.2 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain Spidroin_N PF16763.5 EKX36546.1 - 0.038 14.0 1.3 0.12 12.3 0.2 2.4 3 0 0 3 3 3 0 Major ampullate spidroin 1, spider silk protein 1, N-term PI3K_P85_iSH2 PF16454.5 EKX36546.1 - 0.066 12.8 6.3 0.13 11.8 1.7 2.5 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain HEAT PF02985.22 EKX36546.1 - 0.12 12.7 1.0 1.4e+02 3.2 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat YabA PF06156.13 EKX36546.1 - 0.77 10.4 7.6 0.29 11.8 3.4 2.6 2 1 0 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 EKX36546.1 - 4.3 7.8 10.1 1.2 9.7 5.4 2.6 3 0 0 3 3 3 0 Cell division protein ZapB APG6_N PF17675.1 EKX36546.1 - 8.2 7.0 18.0 0.091 13.3 4.0 3.2 3 0 0 3 3 3 0 Apg6 coiled-coil region bZIP_2 PF07716.15 EKX36546.1 - 9 6.5 11.7 2.1 8.5 5.8 2.7 2 0 0 2 2 2 0 Basic region leucine zipper Thioredoxin PF00085.20 EKX36547.1 - 1.4e-14 53.9 0.3 3.5e-14 52.6 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin EF-hand_1 PF00036.32 EKX36547.1 - 6.3e-11 41.0 2.5 8.2e-05 21.9 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 EKX36547.1 - 1.6e-10 40.0 1.4 0.00019 20.8 0.0 3.8 3 1 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EKX36547.1 - 1.6e-10 40.1 0.1 0.0001 21.9 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EKX36547.1 - 2.3e-09 37.5 0.8 9.4e-09 35.6 0.0 2.4 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 EKX36547.1 - 5.8e-07 29.3 0.1 0.005 16.7 0.0 2.9 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX36547.1 - 0.0004 20.7 0.0 0.00092 19.5 0.0 1.6 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region CDC27 PF09507.10 EKX36550.1 - 1.4e-14 54.4 114.6 6.6e-10 39.0 0.0 4.0 2 1 2 4 4 4 2 DNA polymerase subunit Cdc27 RunxI PF08504.11 EKX36550.1 - 1.1 10.0 4.7 8.4 7.2 4.7 2.6 1 0 0 1 1 1 0 Runx inhibition domain PHO4 PF01384.20 EKX36551.1 - 0.26 10.3 3.6 0.32 10.0 3.6 1.2 1 0 0 1 1 1 0 Phosphate transporter family Ank_2 PF12796.7 EKX36553.1 - 1.7e-19 70.2 0.2 1.4e-10 41.6 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EKX36553.1 - 2.6e-16 59.2 0.8 0.00015 22.0 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EKX36553.1 - 2e-15 57.0 0.2 3.9e-07 30.5 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX36553.1 - 1.6e-11 43.4 0.2 0.0054 17.1 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EKX36553.1 - 2.8e-11 43.4 0.5 3.1e-06 27.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) RsdA_SigD_bd PF16751.5 EKX36553.1 - 0.069 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Anti-sigma-D factor RsdA to sigma factor binding region Ank_3 PF13606.6 EKX36554.1 - 1.7e-09 37.1 0.0 0.00021 21.4 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EKX36554.1 - 2e-09 37.9 0.0 2.1e-09 37.8 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX36554.1 - 1.1e-08 35.5 0.3 0.00075 20.0 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX36554.1 - 1.7e-07 31.4 1.6 0.00048 20.4 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX36554.1 - 0.00071 19.9 0.1 0.3 11.6 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Sulfotransfer_4 PF17784.1 EKX36554.1 - 0.089 12.6 0.0 0.096 12.5 0.0 1.0 1 0 0 1 1 1 0 Sulfotransferase domain DUF4106 PF13388.6 EKX36554.1 - 0.12 11.6 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF5632 PF18646.1 EKX36554.1 - 0.16 12.0 0.7 0.35 10.9 0.6 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5632) Phycoerythr_ab PF02972.14 EKX36555.1 - 1.9e-24 85.2 0.1 6.4e-24 83.5 0.0 1.8 2 0 0 2 2 2 1 Phycoerythrin, alpha/beta chain TAT_signal PF10518.9 EKX36555.1 - 0.0023 17.7 3.7 0.0023 17.7 3.7 3.1 2 2 1 3 3 3 1 TAT (twin-arginine translocation) pathway signal sequence MORN PF02493.20 EKX36556.1 - 9.4e-08 31.5 3.1 0.098 12.6 0.2 4.6 5 0 0 5 5 5 3 MORN repeat Bystin PF05291.11 EKX36557.1 - 6.1e-123 409.8 2.9 6.1e-123 409.8 2.9 1.9 2 0 0 2 2 2 1 Bystin ProQ PF04352.13 EKX36557.1 - 0.63 10.0 4.3 0.61 10.0 0.2 2.7 3 0 0 3 3 3 0 ProQ/FINO family U-box PF04564.15 EKX36558.1 - 1.4e-17 63.7 0.0 1.7e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX36558.1 - 7.9e-07 28.8 0.0 1.5e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EKX36558.1 - 0.0028 17.6 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-NOSIP PF15906.5 EKX36558.1 - 0.046 13.9 0.0 0.062 13.4 0.0 1.2 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein DUF2181 PF10223.9 EKX36558.1 - 0.052 13.0 0.0 0.052 13.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2181) zf-C3HC4_2 PF13923.6 EKX36558.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SET PF00856.28 EKX36559.1 - 2.6e-06 27.9 0.0 1.6e-05 25.4 0.0 2.1 2 1 0 2 2 2 1 SET domain cNMP_binding PF00027.29 EKX36560.1 - 3.5e-39 132.8 0.0 6.9e-19 67.7 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain cNMP_binding PF00027.29 EKX36561.1 - 6.8e-41 138.3 0.1 6.2e-20 71.1 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Hydrolase_4 PF12146.8 EKX36562.1 - 7.3e-16 58.1 0.0 7.5e-11 41.8 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EKX36562.1 - 1.7e-10 41.0 0.0 2.5e-08 33.9 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.12 EKX36562.1 - 5.1e-10 38.5 0.1 0.0019 17.0 0.0 3.1 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 EKX36562.1 - 9.6e-10 38.3 0.0 1.5e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EKX36562.1 - 9.1e-07 29.7 0.0 1.4e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 EKX36562.1 - 1e-05 25.6 0.0 0.0035 17.3 0.0 2.2 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 EKX36562.1 - 4.7e-05 23.4 0.0 6.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EKX36562.1 - 9.9e-05 22.2 0.0 0.0065 16.3 0.0 2.8 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase DUF818 PF05677.12 EKX36562.1 - 0.00055 19.0 0.0 0.00066 18.7 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) FSH1 PF03959.13 EKX36562.1 - 0.0016 18.1 0.0 0.0099 15.6 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase (FSH1) DLH PF01738.18 EKX36562.1 - 0.009 15.6 0.0 0.039 13.5 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 EKX36562.1 - 0.011 15.3 0.0 0.57 9.7 0.0 2.2 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Lipase_3 PF01764.25 EKX36562.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 3) zf-DNL PF05180.12 EKX36562.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 DNL zinc finger Thioesterase PF00975.20 EKX36562.1 - 0.18 11.9 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain KIAA1430 PF13879.6 EKX36563.1 - 8.2e-17 61.8 5.8 2e-16 60.6 5.8 1.6 1 0 0 1 1 1 1 KIAA1430 homologue HAD_2 PF13419.6 EKX36564.1 - 1.8e-12 47.7 0.0 2.4e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase zf-RING_11 PF17123.5 EKX36565.1 - 0.11 12.3 0.7 0.21 11.3 0.7 1.5 1 0 0 1 1 1 0 RING-like zinc finger C2 PF00168.30 EKX36566.1 - 0.016 15.5 0.0 0.05 13.9 0.0 1.8 1 0 0 1 1 1 0 C2 domain DUF748 PF05359.11 EKX36567.1 - 0.045 13.9 0.0 0.075 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF748) DNA_pol3_beta PF00712.19 EKX36568.1 - 0.11 12.6 0.0 0.35 11.0 0.0 1.7 2 0 0 2 2 2 0 DNA polymerase III beta subunit, N-terminal domain Uds1 PF15456.6 EKX36572.1 - 0.092 12.9 20.2 0.02 15.0 3.4 2.4 1 1 1 2 2 2 0 Up-regulated During Septation Nsp1_C PF05064.13 EKX36572.1 - 0.35 10.7 8.6 1.6 8.6 5.3 2.2 2 0 0 2 2 2 0 Nsp1-like C-terminal region MutS_IV PF05190.18 EKX36572.1 - 3.1 8.2 7.8 0.99 9.8 1.5 2.5 2 1 0 2 2 2 0 MutS family domain IV WDCP PF15390.6 EKX36572.1 - 3.7 5.8 5.4 5.1 5.3 5.4 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Atg14 PF10186.9 EKX36572.1 - 4.2 6.4 11.7 6.8 5.7 11.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 EKX36572.1 - 4.7 7.7 20.5 10 6.6 18.1 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region Borrelia_P83 PF05262.11 EKX36572.1 - 6.1 5.2 18.1 7.6 4.9 18.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein RRM_1 PF00076.22 EKX36573.1 - 1.6e-15 56.6 0.1 1.5e-10 40.8 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OCRE PF17780.1 EKX36573.1 - 2.6e-14 53.0 12.9 4.8e-14 52.1 12.9 1.4 1 0 0 1 1 1 1 OCRE domain zf-RanBP PF00641.18 EKX36573.1 - 4.8e-07 29.0 3.6 1e-06 27.9 3.6 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zf-C2H2_jaz PF12171.8 EKX36573.1 - 0.02 15.2 0.3 0.056 13.8 0.3 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Rad50_zn_hook PF04423.14 EKX36573.1 - 0.06 13.2 1.1 0.68 9.8 0.0 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C2HC_2 PF13913.6 EKX36573.1 - 0.13 12.2 0.1 0.28 11.1 0.1 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Pkinase PF00069.25 EKX36574.1 - 2.3e-43 148.5 0.0 9.2e-21 74.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EKX36574.1 - 1.6e-16 60.4 0.0 7.6e-11 41.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX36574.1 - 0.12 11.2 0.0 0.22 10.3 0.0 1.5 1 1 0 1 1 1 0 Fungal protein kinase K_channel_TID PF07941.11 EKX36574.1 - 0.29 11.6 7.3 0.89 10.1 7.3 1.9 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain FancD2 PF14631.6 EKX36574.1 - 1.5 6.1 2.5 2.2 5.6 2.5 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease RRM_1 PF00076.22 EKX36575.1 - 2.4e-11 43.3 0.0 1e-10 41.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_4 PF13637.6 EKX36575.1 - 1.4e-08 35.1 1.0 9.9e-06 26.0 0.4 4.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX36575.1 - 1.4e-08 34.8 1.4 6.1e-07 29.6 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX36575.1 - 3.1e-07 30.5 3.2 0.008 16.6 0.0 4.0 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EKX36575.1 - 9e-07 29.4 0.5 5.6e-06 26.8 0.2 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX36575.1 - 2.2e-06 27.6 0.7 0.068 13.8 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Smg4_UPF3 PF03467.15 EKX36575.1 - 0.0012 18.9 0.1 0.0026 17.8 0.1 1.5 1 0 0 1 1 1 1 Smg-4/UPF3 family Ephrin_rec_like PF07699.13 EKX36576.1 - 1.1e-29 102.0 91.2 6.6e-07 29.0 5.7 9.5 2 2 8 10 10 10 10 Putative ephrin-receptor like NCD3G PF07562.14 EKX36576.1 - 6.6e-16 58.0 65.6 0.0033 17.4 2.7 7.9 5 2 1 8 8 8 8 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX36576.1 - 0.00068 20.0 67.8 0.7 10.3 1.1 11.1 1 1 15 16 16 16 10 TNFR/NGFR cysteine-rich region VSP PF03302.13 EKX36576.1 - 0.01 14.8 75.4 0.49 9.2 20.1 4.0 1 1 3 4 4 4 0 Giardia variant-specific surface protein PA PF02225.22 EKX36577.1 - 1.2e-07 31.7 0.1 2.2e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 PA domain Pyridoxal_deC PF00282.19 EKX36578.1 - 3.3e-17 62.3 0.0 4.7e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EKX36578.1 - 6.1e-09 35.3 0.1 1.3e-08 34.2 0.1 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EKX36578.1 - 0.00023 20.6 0.3 0.00035 20.0 0.3 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EKX36578.1 - 0.0023 16.6 0.0 0.0036 15.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme RWP-RK PF02042.15 EKX36579.1 - 1.1e-17 63.7 0.1 2e-17 62.9 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain Cro PF09048.10 EKX36579.1 - 0.068 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Cro DNA_pol3_delta2 PF13177.6 EKX36580.1 - 9.3e-15 54.8 0.0 6e-10 39.1 0.1 2.3 2 0 0 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 EKX36580.1 - 5.5e-14 52.7 0.0 1.1e-13 51.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 EKX36580.1 - 3e-13 50.0 0.0 1.5e-12 47.7 0.0 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain Rad17 PF03215.15 EKX36580.1 - 5.4e-11 42.7 0.0 3.3e-10 40.2 0.0 2.2 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 EKX36580.1 - 1.9e-05 25.0 0.3 0.00014 22.1 0.3 2.4 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 EKX36580.1 - 4.4e-05 23.0 0.1 0.028 13.8 0.0 2.3 1 1 1 2 2 2 2 Bacterial TniB protein AAA_11 PF13086.6 EKX36580.1 - 4.5e-05 23.4 0.0 0.00016 21.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EKX36580.1 - 7.3e-05 23.2 0.0 0.00035 21.0 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EKX36580.1 - 0.00015 21.6 0.0 0.00029 20.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 EKX36580.1 - 0.00017 21.9 0.0 0.00035 20.9 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA_5 PF07728.14 EKX36580.1 - 0.0002 21.4 0.7 0.00092 19.2 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 EKX36580.1 - 0.00038 19.7 0.0 0.00076 18.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 EKX36580.1 - 0.00071 19.6 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EKX36580.1 - 0.00097 18.9 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EKX36580.1 - 0.0013 18.3 0.0 0.0041 16.7 0.0 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 EKX36580.1 - 0.0014 18.4 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 EKX36580.1 - 0.0052 17.0 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ResIII PF04851.15 EKX36580.1 - 0.0072 16.3 0.0 0.22 11.5 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1068 PF06364.12 EKX36580.1 - 0.0099 15.8 0.1 0.017 15.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1068) AAA_3 PF07726.11 EKX36580.1 - 0.01 15.7 0.0 0.03 14.2 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 EKX36580.1 - 0.018 14.8 0.0 0.029 14.2 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_18 PF13238.6 EKX36580.1 - 0.021 15.4 0.0 0.071 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EKX36580.1 - 0.021 15.1 0.2 0.086 13.2 0.2 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 EKX36580.1 - 0.024 14.1 0.2 5.2 6.5 0.1 2.3 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.21 EKX36580.1 - 0.056 12.8 0.0 0.33 10.3 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EKX36580.1 - 0.09 12.3 0.0 0.21 11.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EKX36580.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 EKX36580.1 - 0.1 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EKX36580.1 - 0.13 12.6 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Pepdidase_M14_N PF18027.1 EKX36581.1 - 0.083 13.2 0.1 0.68 10.3 0.1 2.1 2 0 0 2 2 2 0 Cytosolic carboxypeptidase N-terminal domain ATP-cone PF03477.16 EKX36581.1 - 1.5 9.4 5.2 3.1 8.4 0.4 3.1 3 0 0 3 3 3 0 ATP cone domain WD40_4 PF16300.5 EKX36582.1 - 1.8e-08 34.1 0.0 3.3e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 EKX36582.1 - 0.00021 22.0 2.2 0.03 15.2 0.2 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat Shugoshin_N PF07558.11 EKX36582.1 - 0.00076 19.3 2.4 0.0013 18.5 2.4 1.4 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region bZIP_2 PF07716.15 EKX36582.1 - 0.0065 16.5 3.0 0.011 15.9 3.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper PKcGMP_CC PF16808.5 EKX36582.1 - 0.028 14.3 3.3 0.052 13.4 3.3 1.3 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HSBP1 PF06825.12 EKX36582.1 - 0.14 12.1 0.3 0.23 11.3 0.3 1.3 1 0 0 1 1 1 0 Heat shock factor binding protein 1 M PF02370.16 EKX36582.1 - 0.25 12.0 1.8 0.94 10.2 1.8 2.0 1 0 0 1 1 1 0 M protein repeat Mto2_bdg PF12808.7 EKX36582.1 - 3.1 8.2 6.6 7.5 6.9 5.6 2.0 1 1 1 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Peptidase_C26 PF07722.13 EKX36584.1 - 5.6e-35 121.1 0.0 6.4e-34 117.6 0.0 2.1 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 EKX36584.1 - 2.8e-08 33.7 0.0 4.4e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CRM1_repeat PF18777.1 EKX36585.1 - 8.9e-09 34.7 2.3 3.3 7.3 0.0 5.4 5 0 0 5 5 5 4 Chromosome region maintenance or exportin repeat WAPL PF07814.13 EKX36585.1 - 2.2e-08 33.3 15.8 0.14 10.9 0.0 6.7 6 1 0 7 7 7 4 Wings apart-like protein regulation of heterochromatin V-ATPase_H_N PF03224.14 EKX36585.1 - 1.2e-06 28.0 2.4 1.4 8.2 0.1 6.2 5 1 0 6 6 6 2 V-ATPase subunit H Alkyl_sulf_dimr PF14863.6 EKX36585.1 - 1.4e-06 28.9 21.3 1.5 9.3 0.3 8.7 6 3 3 9 9 9 4 Alkyl sulfatase dimerisation Rcd1 PF04078.13 EKX36585.1 - 7.1e-05 22.2 3.8 8.4 5.6 0.1 4.9 4 0 0 4 4 4 2 Cell differentiation family, Rcd1-like RTP1_C1 PF10363.9 EKX36585.1 - 9e-05 22.6 2.2 0.89 9.8 0.0 5.0 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Glyco_hydro_36 PF17167.4 EKX36585.1 - 0.00011 21.1 0.2 5.3 5.6 0.0 3.3 3 0 0 3 3 3 3 Glycosyl hydrolase 36 superfamily, catalytic domain Arm PF00514.23 EKX36585.1 - 0.0012 18.8 13.5 28 4.9 0.0 9.6 12 0 0 12 12 10 0 Armadillo/beta-catenin-like repeat RICTOR_N PF14664.6 EKX36585.1 - 0.0015 17.6 13.2 2.7 6.9 0.1 6.5 5 3 2 7 7 7 3 Rapamycin-insensitive companion of mTOR, N-term DUF5578 PF17741.1 EKX36585.1 - 0.02 14.3 12.3 10 5.5 0.1 6.4 6 1 0 6 6 6 0 Family of unknown function (DUF5578) CRIC_ras_sig PF10534.9 EKX36585.1 - 0.078 13.2 0.0 33 4.7 0.0 3.1 2 0 0 2 2 2 0 Connector enhancer of kinase suppressor of ras Tti2 PF10521.9 EKX36585.1 - 0.11 12.0 2.3 1.3e+02 2.0 0.0 4.8 5 0 0 5 5 5 0 Tti2 family DUF1180 PF06679.12 EKX36585.1 - 1.5 9.2 8.1 91 3.4 0.1 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1180) ANAPC4_WD40 PF12894.7 EKX36586.1 - 1e-28 99.5 0.0 0.011 16.0 0.0 9.0 4 3 5 9 9 9 7 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EKX36586.1 - 6.7e-09 35.7 0.8 0.00078 19.1 0.3 2.9 1 1 0 2 2 2 2 PQQ-like domain CNH PF00780.22 EKX36586.1 - 1.6e-06 28.0 2.4 1.9 8.0 0.0 7.0 8 1 1 9 9 9 2 CNH domain WD40 PF00400.32 EKX36586.1 - 2.5e-06 28.1 0.0 9.7 7.3 0.0 5.8 5 0 0 5 5 4 1 WD domain, G-beta repeat Nup160 PF11715.8 EKX36586.1 - 5.1e-05 22.1 0.0 5 5.6 0.0 5.2 2 2 1 5 5 5 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EKX36586.1 - 9.8e-05 21.0 1.6 0.34 9.4 0.0 3.6 2 1 1 4 4 4 2 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 EKX36586.1 - 0.00087 18.3 0.0 1.9 7.4 0.0 4.7 2 1 4 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_S9_N PF02897.15 EKX36586.1 - 0.0012 17.8 0.1 3.6 6.3 0.0 4.1 4 1 1 5 5 5 2 Prolyl oligopeptidase, N-terminal beta-propeller domain Nbas_N PF15492.6 EKX36586.1 - 0.0021 17.5 0.1 0.22 10.8 0.0 3.4 1 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal PALB2_WD40 PF16756.5 EKX36586.1 - 0.004 16.1 0.1 6.8 5.5 0.0 4.1 4 1 1 5 5 5 1 Partner and localizer of BRCA2 WD40 domain FecR PF04773.13 EKX36586.1 - 0.0066 17.1 0.9 7.6 7.2 0.0 4.0 4 0 0 4 4 4 1 FecR protein Nucleoporin_N PF08801.11 EKX36586.1 - 0.015 14.1 0.1 3.5 6.3 0.0 3.4 3 1 1 4 4 4 0 Nup133 N terminal like Vault_4 PF17796.1 EKX36586.1 - 0.04 14.0 5.4 12 6.0 0.0 4.5 5 0 0 5 5 5 0 Major Vault Protein repeat domain Gmad1 PF10647.9 EKX36586.1 - 0.041 13.6 1.8 0.23 11.2 0.1 2.6 3 0 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain NUP214 PF16755.5 EKX36586.1 - 0.076 12.2 0.0 0.82 8.8 0.0 2.3 3 0 0 3 3 3 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 PRY PF13765.6 EKX36586.1 - 0.089 12.4 0.0 17 5.2 0.0 2.5 2 0 0 2 2 2 0 SPRY-associated domain SPC25 PF06703.11 EKX36587.1 - 1.2e-34 119.5 0.0 1.5e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) RWP-RK PF02042.15 EKX36588.1 - 8.3e-14 51.3 0.0 1.4e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain Sigma70_r4_2 PF08281.12 EKX36588.1 - 0.024 14.3 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 DUF4859 PF16151.5 EKX36588.1 - 0.058 13.3 0.0 0.084 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4859) RWP-RK PF02042.15 EKX36589.1 - 2.9e-14 52.8 0.2 1.6e-13 50.4 0.0 1.9 2 0 0 2 2 2 1 RWP-RK domain Sigma70_r4_2 PF08281.12 EKX36589.1 - 0.025 14.3 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 DUF4859 PF16151.5 EKX36589.1 - 0.028 14.3 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4859) RWP-RK PF02042.15 EKX36590.1 - 1.6e-13 50.4 0.0 2.8e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain Peptidase_C2 PF00648.21 EKX36591.1 - 1.4e-12 47.3 0.0 2.3e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Fungus-induced PF10917.8 EKX36591.1 - 0.26 11.6 4.4 0.7 10.3 4.4 1.7 1 0 0 1 1 1 0 Fungus-induced protein DUF4813 PF16072.5 EKX36591.1 - 1.9 8.1 3.4 2.6 7.6 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Peptidase_C2 PF00648.21 EKX36592.1 - 0.0018 17.4 0.1 0.0021 17.1 0.1 1.0 1 0 0 1 1 1 1 Calpain family cysteine protease IF4E PF01652.18 EKX36593.1 - 8.9e-33 113.3 0.0 9.9e-33 113.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E CSN5_C PF18323.1 EKX36597.1 - 0.063 14.2 0.3 0.11 13.4 0.3 1.4 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain Complex1_LYR PF05347.15 EKX36598.1 - 1.4e-05 25.0 0.7 1.9e-05 24.6 0.7 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Glyco_transf_5 PF08323.11 EKX36600.1 - 8.6e-55 186.1 0.0 1.2e-54 185.6 0.0 1.2 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EKX36600.1 - 1.4e-13 50.8 0.0 2.5e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EKX36600.1 - 0.00023 21.2 0.0 0.039 14.0 0.0 2.7 3 0 0 3 3 3 2 Glycosyltransferase Family 4 Tox-REase-5 PF15648.6 EKX36600.1 - 0.0012 19.2 0.1 0.025 15.1 0.0 2.5 2 0 0 2 2 2 1 Restriction endonuclease fold toxin 5 Glyco_trans_4_4 PF13579.6 EKX36600.1 - 0.013 15.9 0.0 0.24 11.8 0.0 2.7 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain Asp PF00026.23 EKX36601.1 - 1.8e-19 70.3 0.0 1.5e-12 47.6 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EKX36601.1 - 2.9e-08 34.2 1.8 0.00078 19.7 0.0 2.8 3 0 0 3 3 3 2 Xylanase inhibitor N-terminal Zip PF02535.22 EKX36601.1 - 0.042 13.1 0.9 0.06 12.5 0.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Connexin PF00029.19 EKX36601.1 - 0.13 12.1 0.8 0.19 11.5 0.8 1.2 1 0 0 1 1 1 0 Connexin RICTOR_N PF14664.6 EKX36601.1 - 0.22 10.5 1.3 0.34 9.8 1.3 1.2 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Ephrin_rec_like PF07699.13 EKX36603.1 - 6.9e-33 112.2 76.8 1.4e-06 28.0 1.9 8.5 2 2 6 8 8 8 8 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX36603.1 - 9.7e-07 29.1 53.3 0.34 11.3 1.1 9.3 2 2 4 7 7 7 5 TNFR/NGFR cysteine-rich region VSP PF03302.13 EKX36603.1 - 1.5 7.6 75.0 0.22 10.3 24.0 3.9 1 1 3 4 4 4 0 Giardia variant-specific surface protein cNMP_binding PF00027.29 EKX36606.1 - 1.7e-14 53.6 0.2 4.8e-06 26.5 0.0 2.9 2 1 1 3 3 3 2 Cyclic nucleotide-binding domain RRM_1 PF00076.22 EKX36608.1 - 2.4e-09 36.9 0.1 0.001 18.9 0.0 3.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc PF12871.7 EKX36608.1 - 6.6e-05 23.5 51.0 6.6e-05 23.5 51.0 4.8 2 1 1 3 3 3 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term RRM_occluded PF16842.5 EKX36608.1 - 0.00035 20.4 0.2 0.33 10.9 0.0 3.5 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_5 PF13893.6 EKX36608.1 - 0.069 12.8 0.0 0.31 10.6 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Leu_zip PF15294.6 EKX36609.1 - 0.00052 19.6 4.0 0.00052 19.6 4.0 3.6 1 1 0 2 2 2 1 Leucine zipper Syntaxin-6_N PF09177.11 EKX36609.1 - 0.0021 18.6 2.0 0.0021 18.6 2.0 4.7 3 2 2 5 5 5 1 Syntaxin 6, N-terminal CALCOCO1 PF07888.11 EKX36609.1 - 1.3 7.9 47.1 0.012 14.5 23.2 3.2 1 1 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like BLOC1_2 PF10046.9 EKX36609.1 - 1.6 9.1 30.2 5 7.5 0.3 6.0 2 2 4 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 T3SSipB PF16535.5 EKX36609.1 - 2.3 8.7 14.3 6.7 7.2 9.2 2.8 1 1 2 3 3 3 0 Type III cell invasion protein SipB DUF4795 PF16043.5 EKX36609.1 - 8.5 5.9 37.5 2.5 7.7 7.0 3.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) ATG16 PF08614.11 EKX36609.1 - 9.5 6.4 43.8 0.22 11.7 1.3 4.1 2 2 2 4 4 4 0 Autophagy protein 16 (ATG16) HMA PF00403.26 EKX36610.1 - 1.9e-23 82.6 6.9 2.4e-10 40.7 0.2 3.5 4 0 0 4 4 4 2 Heavy-metal-associated domain Tap-RNA_bind PF09162.10 EKX36610.1 - 0.051 13.4 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 Tap, RNA-binding Sporozoite_P67 PF05642.11 EKX36610.1 - 0.094 10.8 6.6 0.12 10.4 6.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ion_trans PF00520.31 EKX36611.1 - 3.1e-30 105.2 22.0 4.3e-30 104.7 22.0 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EKX36611.1 - 1.5e-05 23.9 9.8 1.5e-05 23.9 9.8 1.8 2 0 0 2 2 2 1 Polycystin cation channel MMtag PF10159.9 EKX36612.1 - 6e-18 64.9 1.7 6.9e-18 64.7 1.7 1.1 1 0 0 1 1 1 1 Multiple myeloma tumor-associated LRR_8 PF13855.6 EKX36613.1 - 9.7e-77 252.7 65.0 2.2e-16 59.4 2.2 7.3 2 1 6 8 8 8 8 Leucine rich repeat LRR_5 PF13306.6 EKX36613.1 - 5.9e-38 129.7 32.7 1.1e-11 44.8 3.4 3.9 1 1 4 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 EKX36613.1 - 7.2e-26 89.8 43.3 2.5e-06 27.7 1.5 8.2 4 3 3 9 9 9 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX36613.1 - 7.7e-14 51.6 1.1 2.9e-05 23.6 0.0 4.4 1 1 2 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.33 EKX36613.1 - 2.7e-10 39.3 31.9 0.37 11.5 0.0 10.7 10 1 0 10 10 10 4 Leucine Rich Repeat DUF3760 PF12586.8 EKX36613.1 - 0.0023 18.1 0.2 6.9 6.9 0.0 4.1 4 0 0 4 4 4 1 Protein of unknown function (DUF3760) LRR_6 PF13516.6 EKX36613.1 - 0.033 14.3 35.6 0.2 11.8 0.0 9.0 10 0 0 10 10 10 0 Leucine Rich repeat LRR_8 PF13855.6 EKX36614.1 - 7e-80 262.7 35.7 4.3e-17 61.6 0.0 6.0 2 1 4 6 6 6 6 Leucine rich repeat LRR_5 PF13306.6 EKX36614.1 - 1.6e-41 141.3 2.6 1.4e-11 44.4 0.0 3.1 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 EKX36614.1 - 8.9e-35 118.2 27.8 4.3e-07 30.1 0.2 6.4 5 1 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX36614.1 - 2.6e-17 60.7 25.5 0.11 13.1 0.0 10.6 11 1 0 11 11 11 6 Leucine Rich Repeat LRR_9 PF14580.6 EKX36614.1 - 1.3e-15 57.4 0.0 5e-06 26.1 0.0 4.6 2 1 3 5 5 5 5 Leucine-rich repeat LRR_6 PF13516.6 EKX36614.1 - 1.3 9.3 0.0 1.3 9.3 0.0 8.1 9 0 0 9 9 9 0 Leucine Rich repeat WD40 PF00400.32 EKX36616.1 - 1.9e-23 82.3 11.5 7.8e-06 26.5 0.3 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat CAP_GLY PF01302.25 EKX36616.1 - 8e-19 67.4 1.8 9e-19 67.3 0.5 1.8 2 0 0 2 2 2 1 CAP-Gly domain ANAPC4_WD40 PF12894.7 EKX36616.1 - 3.5e-07 30.4 0.4 0.0002 21.6 0.1 3.4 2 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EKX36616.1 - 4e-06 27.1 8.3 6.9 7.3 0.0 6.4 5 1 1 6 6 6 2 PQQ-like domain PQQ_2 PF13360.6 EKX36616.1 - 0.0055 16.3 2.0 0.016 14.8 1.2 2.2 1 1 1 2 2 2 1 PQQ-like domain PQQ PF01011.21 EKX36616.1 - 0.0064 16.4 4.1 0.23 11.5 0.1 3.9 5 0 0 5 5 5 1 PQQ enzyme repeat F5_F8_type_C PF00754.25 EKX36618.1 - 0.0033 17.5 0.1 0.011 15.9 0.0 1.8 2 0 0 2 2 2 1 F5/8 type C domain Tctex-1 PF03645.13 EKX36618.1 - 2 8.7 5.0 14 6.0 0.1 3.0 2 1 1 3 3 3 0 Tctex-1 family PDZ_6 PF17820.1 EKX36619.1 - 3.3e-14 52.5 0.1 7.3e-14 51.3 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX36619.1 - 1.6e-08 34.7 0.1 3.8e-08 33.6 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX36619.1 - 3.3e-08 33.8 0.4 5.9e-08 32.9 0.4 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX36619.1 - 0.023 14.7 0.6 0.057 13.4 0.0 2.0 3 0 0 3 3 3 0 Tricorn protease PDZ domain Sin_N PF04801.13 EKX36620.1 - 1.9e-24 86.7 20.7 2.5e-18 66.5 1.5 3.9 2 2 1 3 3 3 2 Sin-like protein conserved region Phage_sheath_1N PF17481.2 EKX36620.1 - 0.016 15.6 0.3 0.035 14.6 0.3 1.5 1 0 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain Sin_N PF04801.13 EKX36621.1 - 2.7e-29 102.7 0.0 9.1e-16 58.1 0.0 2.0 1 1 1 2 2 2 2 Sin-like protein conserved region ATP_bind_3 PF01171.20 EKX36623.1 - 3.6e-06 26.9 0.0 4e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 PP-loop family V-ATPase_G PF03179.15 EKX36624.1 - 6.7e-27 94.1 12.0 7.4e-27 93.9 12.0 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 EKX36624.1 - 0.022 14.2 13.6 0.028 13.8 13.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) EssA PF10661.9 EKX36624.1 - 0.03 14.2 3.6 0.035 13.9 3.6 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA Macoilin PF09726.9 EKX36624.1 - 0.057 12.0 8.5 0.066 11.8 8.5 1.0 1 0 0 1 1 1 0 Macoilin family DUF1640 PF07798.11 EKX36624.1 - 0.067 13.2 6.4 0.19 11.8 6.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF2203 PF09969.9 EKX36624.1 - 0.21 12.3 7.0 0.19 12.4 5.5 1.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4472 PF14739.6 EKX36624.1 - 0.23 12.2 7.9 0.33 11.7 7.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4472) Com_YlbF PF06133.11 EKX36624.1 - 0.29 11.7 10.4 0.5 11.0 10.0 1.5 1 1 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA DUF883 PF05957.13 EKX36624.1 - 0.44 11.2 10.5 1.1 10.0 7.9 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) CemA PF03040.14 EKX36624.1 - 0.59 10.0 2.9 0.65 9.9 2.9 1.1 1 0 0 1 1 1 0 CemA family RNAse_A_bac PF18431.1 EKX36624.1 - 0.96 10.4 5.5 1.6 9.7 5.5 1.3 1 1 0 1 1 1 0 Bacterial CdiA-CT RNAse A domain TMPIT PF07851.13 EKX36624.1 - 1.1 8.4 4.7 1.2 8.3 4.7 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 EKX36624.1 - 1.1 8.5 8.3 1.3 8.3 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V-ATPase_G_2 PF16999.5 EKX36624.1 - 1.1 9.7 17.4 2.7 8.5 17.4 1.6 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit Atg14 PF10186.9 EKX36624.1 - 1.3 8.0 8.8 1.5 7.8 8.8 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HAUS-augmin3 PF14932.6 EKX36624.1 - 1.6 8.2 10.8 4.6 6.8 10.3 1.8 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 EMC3_TMCO1 PF01956.16 EKX36624.1 - 2.7 7.7 4.4 3 7.5 4.4 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like G-gamma PF00631.22 EKX36624.1 - 3.4 7.8 5.0 0.77 9.8 0.4 2.2 2 1 1 3 3 3 0 GGL domain ATP-synt_B PF00430.18 EKX36624.1 - 5.2 7.2 19.9 22 5.1 19.9 1.8 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) HAUS6_N PF14661.6 EKX36624.1 - 8.6 5.9 9.6 9.9 5.7 9.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Spt5-NGN PF03439.13 EKX36625.1 - 1.4e-19 69.7 0.1 3e-19 68.7 0.1 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 EKX36625.1 - 1.9e-16 59.4 58.4 2.3e-05 24.2 2.3 8.3 9 0 0 9 9 9 7 KOW motif PCB_OB PF17092.5 EKX36625.1 - 0.0056 17.4 4.4 12 6.7 0.0 4.2 3 0 0 3 3 3 2 Penicillin-binding protein OB-like domain SDA1 PF05285.12 EKX36625.1 - 8.7 5.7 40.7 13 5.0 40.7 1.3 1 0 0 1 1 1 0 SDA1 Zn_clus PF00172.18 EKX36626.1 - 3.9e-05 23.7 13.5 6.8e-05 22.9 13.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 EKX36627.1 - 3.3e-05 23.9 13.5 5.1e-05 23.3 13.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 EKX36628.1 - 1.1e-05 25.4 27.0 2.5e-05 24.3 14.2 3.4 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain PMG PF05287.12 EKX36628.1 - 0.014 15.4 4.0 0.014 15.4 4.0 2.8 3 0 0 3 3 3 0 PMG protein DUF4701 PF15773.5 EKX36628.1 - 0.1 11.6 1.7 0.82 8.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4701) DNA_binding_1 PF01035.20 EKX36628.1 - 0.11 12.7 0.1 0.32 11.1 0.1 1.8 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, DNA binding domain Pes-10 PF07149.11 EKX36629.1 - 0.094 11.8 7.1 0.12 11.4 7.1 1.2 1 0 0 1 1 1 0 Pes-10 CENP-B_dimeris PF09026.10 EKX36629.1 - 0.11 12.9 7.9 0.17 12.3 7.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sporozoite_P67 PF05642.11 EKX36629.1 - 0.11 10.6 2.6 0.11 10.6 2.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen eIF-3c_N PF05470.12 EKX36629.1 - 0.12 10.7 3.4 0.13 10.6 3.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus HTH_10 PF04967.12 EKX36629.1 - 0.14 12.0 0.4 0.71 9.7 0.0 2.2 2 1 0 2 2 2 0 HTH DNA binding domain Spt5_N PF11942.8 EKX36629.1 - 5.8 8.0 12.5 4.5 8.3 9.3 2.0 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Ribosomal_L29e PF01779.17 EKX36630.1 - 2.3e-21 75.8 11.1 2.3e-21 75.8 11.1 1.9 2 0 0 2 2 2 1 Ribosomal L29e protein family TAL_FSA PF00923.19 EKX36632.1 - 5.7e-35 121.1 0.0 1.3e-33 116.6 0.0 2.0 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Glu_syn_central PF04898.14 EKX36632.1 - 0.028 13.9 0.3 0.15 11.5 0.1 1.8 1 1 0 2 2 2 0 Glutamate synthase central domain Orn_Arg_deC_N PF02784.16 EKX36633.1 - 4e-77 258.9 0.0 5.7e-77 258.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EKX36633.1 - 1.3e-11 44.5 0.0 1.9e-11 44.0 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain LRR_6 PF13516.6 EKX36634.1 - 6.7e-09 35.1 4.0 0.00021 21.1 0.0 4.5 4 1 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 EKX36634.1 - 0.0052 17.2 0.2 10 6.7 0.0 3.3 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) DUF3046 PF11248.8 EKX36634.1 - 0.062 13.7 0.0 0.53 10.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3046) LRR_1 PF00560.33 EKX36634.1 - 0.089 13.4 0.5 12 6.9 0.0 3.5 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.6 EKX36634.1 - 0.39 10.5 1.6 19 5.1 0.1 2.8 2 1 0 2 2 2 0 Leucine rich repeat Dopey_N PF04118.14 EKX36635.1 - 5.5e-59 199.8 0.0 6.7e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 Dopey, N-terminal Csm1_N PF18504.1 EKX36638.1 - 0.054 13.8 0.1 0.11 12.8 0.1 1.6 1 1 0 1 1 1 0 Csm1 N-terminal domain C2 PF00168.30 EKX36639.1 - 2.4e-21 75.9 0.0 2.4e-20 72.7 0.0 2.4 2 0 0 2 2 2 1 C2 domain WW PF00397.26 EKX36639.1 - 1.2e-06 28.4 5.6 1.2e-06 28.4 5.6 1.9 2 0 0 2 2 2 1 WW domain PDZ_6 PF17820.1 EKX36639.1 - 0.0085 15.9 0.0 0.026 14.4 0.0 1.9 1 0 0 1 1 1 1 PDZ domain Transformer PF06495.11 EKX36639.1 - 0.0091 16.1 0.9 0.025 14.7 0.9 1.7 1 0 0 1 1 1 1 Fruit fly transformer protein zf-RING_2 PF13639.6 EKX36640.1 - 3.1e-12 46.6 7.8 5.9e-12 45.7 7.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EKX36640.1 - 1.1e-11 44.2 5.7 2.6e-11 43.1 5.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EKX36640.1 - 7.6e-07 28.9 7.8 1.4e-06 28.1 7.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX36640.1 - 6.8e-06 26.0 4.7 1.3e-05 25.1 4.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EKX36640.1 - 1.5e-05 24.7 10.0 3.6e-05 23.5 10.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX36640.1 - 5.4e-05 23.4 9.6 0.00019 21.6 9.6 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EKX36640.1 - 0.0002 21.2 7.2 0.00048 20.0 7.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EKX36640.1 - 0.002 18.1 6.1 0.0051 16.8 5.5 1.9 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EKX36640.1 - 0.0029 17.4 5.8 0.0062 16.4 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EKX36640.1 - 0.003 17.7 3.7 0.0074 16.4 3.7 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 EKX36640.1 - 0.0091 15.6 6.6 0.02 14.5 6.6 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-HC5HC2H_2 PF13832.6 EKX36640.1 - 0.019 15.1 1.0 0.04 14.1 1.0 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EKX36640.1 - 0.067 13.5 2.5 0.15 12.4 2.5 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_4 PF14570.6 EKX36640.1 - 0.22 11.3 5.0 0.4 10.5 5.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 EKX36640.1 - 0.35 11.0 8.0 0.79 9.9 8.0 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 EKX36640.1 - 0.65 10.2 5.9 2 8.7 5.9 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EKX36640.1 - 0.72 9.8 7.7 1.4 8.9 7.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.29 EKX36640.1 - 0.9 9.5 7.3 1.7 8.6 7.3 1.5 1 0 0 1 1 1 0 PHD-finger UVR PF02151.19 EKX36641.1 - 6.6e-07 28.9 25.8 0.0013 18.4 1.1 4.7 4 0 0 4 4 4 4 UvrB/uvrC motif HTH_56 PF18662.1 EKX36641.1 - 0.1 12.7 2.4 4.6 7.4 0.2 2.7 2 1 0 2 2 2 0 Cch helix turn helix domain Mucin15 PF15672.5 EKX36641.1 - 0.16 11.5 3.0 0.06 12.8 0.3 1.6 2 0 0 2 2 2 0 Cell-membrane associated Mucin15 CobU PF02283.16 EKX36641.1 - 4.2 6.9 8.1 1.4 8.5 4.9 1.7 1 1 1 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase adh_short PF00106.25 EKX36642.1 - 1.1e-06 28.3 0.0 0.015 14.8 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EKX36642.1 - 4.6e-06 26.4 0.0 0.027 14.1 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase TylF PF05711.11 EKX36645.1 - 8.4e-52 176.0 0.0 1.7e-51 175.0 0.0 1.5 1 1 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.6 EKX36645.1 - 1.1e-06 29.7 0.0 2.3e-06 28.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Sulf_transp PF04143.14 EKX36646.1 - 5.9e-41 141.0 31.7 5.9e-41 141.0 31.7 2.0 1 1 1 2 2 2 1 Sulphur transport UL42 PF17638.2 EKX36646.1 - 0.46 10.5 2.0 0.48 10.4 0.0 2.0 2 0 0 2 2 2 0 HCMV UL42 Pkinase_Tyr PF07714.17 EKX36647.1 - 3.2e-33 115.1 0.0 1.1e-30 106.9 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 EKX36647.1 - 2.3e-32 112.4 0.0 4.9e-30 104.8 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain APH PF01636.23 EKX36647.1 - 0.0054 16.7 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX36647.1 - 0.14 10.9 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase DUF4177 PF13783.6 EKX36648.1 - 0.085 13.2 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) TMV_coat PF00721.21 EKX36648.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Virus coat protein (TMV like) Pyr_redox PF00070.27 EKX36650.1 - 1.7e-05 25.3 1.9 0.00053 20.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EKX36650.1 - 0.0003 20.1 3.3 0.0054 16.0 0.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AIF_C PF14721.6 EKX36650.1 - 0.00037 20.8 0.0 0.00093 19.6 0.0 1.7 2 0 0 2 2 2 1 Apoptosis-inducing factor, mitochondrion-associated, C-term NAD_binding_7 PF13241.6 EKX36650.1 - 0.0018 18.7 0.7 0.031 14.7 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 EKX36650.1 - 0.012 14.9 0.1 0.43 9.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cupin_3 PF05899.12 EKX36653.1 - 1.8e-24 85.2 0.1 1.9e-24 85.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 EKX36653.1 - 6.3e-07 29.0 0.0 7e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 EKX36653.1 - 4.3e-06 26.6 0.0 4.4e-06 26.5 0.0 1.0 1 0 0 1 1 1 1 Cupin EutQ PF06249.12 EKX36653.1 - 0.00023 21.0 0.0 0.00027 20.7 0.0 1.0 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_1 PF00190.22 EKX36653.1 - 0.0027 17.3 0.0 0.0033 17.1 0.0 1.1 1 0 0 1 1 1 1 Cupin PRTP PF01366.18 EKX36653.1 - 0.058 11.4 0.0 0.059 11.4 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein His_Phos_1 PF00300.22 EKX36654.1 - 3.3e-11 43.2 0.1 7.9e-11 42.0 0.1 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Beta_helix PF13229.6 EKX36654.1 - 1e-06 28.7 0.4 2e-06 27.7 0.4 1.3 1 0 0 1 1 1 1 Right handed beta helix region Aminotran_1_2 PF00155.21 EKX36654.1 - 0.00011 21.5 0.3 0.00025 20.3 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II NosD PF05048.13 EKX36654.1 - 0.0079 15.5 0.1 0.015 14.6 0.1 1.4 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) N6_N4_Mtase PF01555.18 EKX36654.1 - 0.12 12.0 0.2 0.22 11.2 0.2 1.3 1 0 0 1 1 1 0 DNA methylase Cyt_bd_oxida_II PF02322.15 EKX36654.1 - 9.9 5.4 13.9 16 4.7 13.9 1.2 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II SPT16 PF08644.11 EKX36655.1 - 5.3e-41 140.3 0.0 5.3e-41 140.3 0.0 2.6 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 EKX36655.1 - 4.9e-23 81.7 0.2 4.9e-23 81.7 0.2 2.8 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 EKX36655.1 - 3.3e-15 56.4 0.0 5e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 UCH_N PF16674.5 EKX36655.1 - 0.027 14.4 0.1 0.08 12.9 0.1 1.8 1 0 0 1 1 1 0 N-terminal of ubiquitin carboxyl-terminal hydrolase 37 SET PF00856.28 EKX36655.1 - 0.061 13.7 0.3 0.16 12.3 0.3 1.7 1 0 0 1 1 1 0 SET domain Presenilin PF01080.17 EKX36655.1 - 2.6 6.7 5.1 9.7 4.8 4.5 2.0 2 0 0 2 2 2 0 Presenilin zf-CCCH PF00642.24 EKX36656.1 - 3.2e-10 39.7 15.5 1.3e-05 25.0 2.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 EKX36656.1 - 7e-09 35.4 0.1 1.1e-08 34.7 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EKX36656.1 - 0.0003 20.7 15.6 0.0061 16.6 2.4 2.5 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 EKX36656.1 - 0.0017 19.0 1.7 0.79 10.5 0.2 2.5 2 0 0 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 EKX36656.1 - 0.0055 16.5 16.4 0.029 14.2 3.2 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger Nup35_RRM_2 PF14605.6 EKX36656.1 - 0.0083 16.1 0.3 0.017 15.1 0.3 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH_3 PF15663.5 EKX36656.1 - 0.012 15.8 2.2 0.95 9.7 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger containing family EGF_alliinase PF04863.13 EKX36657.1 - 0.12 12.8 1.4 2.6 8.5 0.0 3.0 3 0 0 3 3 3 0 Alliinase EGF-like domain TPR_1 PF00515.28 EKX36659.1 - 1e-46 154.9 7.2 1.5e-09 37.2 0.0 7.8 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 EKX36659.1 - 4.6e-40 132.5 5.1 2e-06 27.5 0.0 7.9 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 EKX36659.1 - 5.7e-36 119.7 6.4 8.1e-06 25.7 0.0 7.6 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 EKX36659.1 - 2.2e-23 81.6 14.3 1.6e-07 30.9 0.5 7.7 5 2 3 8 8 8 5 TPR repeat TPR_17 PF13431.6 EKX36659.1 - 7.4e-23 79.2 8.9 0.0016 18.7 0.1 7.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 EKX36659.1 - 4.6e-22 78.3 0.6 2e-07 31.4 0.1 4.7 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.6 EKX36659.1 - 9.8e-20 70.6 0.1 0.0006 20.0 0.1 5.4 3 1 1 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 EKX36659.1 - 5.5e-19 67.2 0.0 0.0034 18.1 0.0 5.7 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.6 EKX36659.1 - 6.8e-19 66.4 3.0 0.041 13.9 0.0 7.5 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.6 EKX36659.1 - 2.3e-16 59.2 2.6 0.028 15.0 0.2 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX36659.1 - 1.2e-15 57.8 0.0 0.0059 17.2 0.0 5.3 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 EKX36659.1 - 1.1e-10 41.6 0.0 0.25 11.5 0.0 5.2 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_15 PF13429.6 EKX36659.1 - 3.2e-10 39.7 0.1 0.017 14.4 0.2 4.2 1 1 3 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX36659.1 - 4.4e-08 33.2 8.0 1.2e-06 28.6 0.2 3.9 3 1 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 EKX36659.1 - 9.1e-07 28.8 1.4 0.028 14.1 0.0 4.3 2 1 1 4 4 4 2 Tetratricopeptide repeat-like domain MIT PF04212.18 EKX36659.1 - 6.5e-06 26.1 13.1 2.2 8.4 0.1 7.2 8 0 0 8 8 8 2 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 EKX36659.1 - 4.5e-05 23.2 0.3 5.6 7.0 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat SNAP PF14938.6 EKX36659.1 - 6.2e-05 22.6 3.5 0.11 11.9 0.1 3.9 1 1 2 4 4 4 1 Soluble NSF attachment protein, SNAP DUF2225 PF09986.9 EKX36659.1 - 0.00037 20.3 0.8 1.3 8.7 0.0 3.5 1 1 2 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) RPN7 PF10602.9 EKX36659.1 - 0.0038 17.0 1.2 1.2 8.8 0.0 3.3 2 1 0 3 3 3 1 26S proteasome subunit RPN7 DUF1079 PF06435.11 EKX36659.1 - 0.011 15.9 0.4 0.038 14.2 0.4 2.0 1 0 0 1 1 1 0 Repeat of unknown function (DUF1079) ChAPs PF09295.10 EKX36659.1 - 0.019 14.0 0.1 0.24 10.4 0.0 2.1 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF627 PF04781.12 EKX36659.1 - 0.13 12.3 0.0 26 4.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF627) Pentapeptide PF00805.22 EKX36660.1 - 1.1e-12 47.3 7.7 4.9e-06 26.1 1.0 2.7 2 0 0 2 2 2 2 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 EKX36660.1 - 5.6e-09 36.0 2.0 4.6e-06 26.7 0.3 2.2 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) BTB_2 PF02214.22 EKX36660.1 - 7.2e-07 29.5 0.0 1.5e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Pentapeptide_3 PF13576.6 EKX36660.1 - 1.4e-05 25.1 5.9 0.0091 16.1 1.6 2.7 2 0 0 2 2 2 2 Pentapeptide repeats (9 copies) Gly_rich PF12810.7 EKX36660.1 - 0.018 15.0 44.8 0.08 12.8 44.8 2.1 1 1 0 1 1 1 0 Glycine rich protein DUF2652 PF10851.8 EKX36663.1 - 0.084 13.0 0.8 56 3.9 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2652) Phage_HK97_TLTM PF06120.11 EKX36663.1 - 0.16 11.1 10.7 0.32 10.2 9.5 2.0 1 1 1 2 2 2 0 Tail length tape measure protein DUF4473 PF14747.6 EKX36663.1 - 4.6 7.9 7.7 0.48 11.0 0.8 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF4473) DUF1090 PF06476.12 EKX36663.1 - 4.8 7.3 27.8 2 8.6 1.1 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF1090) Cytochrom_C_2 PF01322.20 EKX36665.1 - 0.08 13.8 2.2 0.12 13.2 2.2 1.3 1 1 0 1 1 1 0 Cytochrome C' DUF4473 PF14747.6 EKX36665.1 - 0.082 13.5 1.0 0.19 12.3 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) BIR PF00653.21 EKX36667.1 - 6.4e-12 45.9 0.0 1.5e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain bZIP_1 PF00170.21 EKX36668.1 - 0.022 14.9 1.6 0.022 14.9 1.6 3.1 4 0 0 4 4 4 0 bZIP transcription factor DivIC PF04977.15 EKX36668.1 - 0.11 12.3 6.5 0.21 11.4 0.5 2.9 2 0 0 2 2 2 0 Septum formation initiator SOGA PF11365.8 EKX36668.1 - 0.18 12.9 15.1 1.1 10.5 3.6 3.6 3 1 1 4 4 4 0 Protein SOGA TMCO5 PF14992.6 EKX36668.1 - 0.24 11.0 15.2 0.11 12.1 3.3 3.1 3 0 0 3 3 3 0 TMCO5 family Uso1_p115_C PF04871.13 EKX36668.1 - 0.33 11.3 25.8 0.53 10.7 6.6 3.4 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Med28 PF11594.8 EKX36668.1 - 0.4 10.8 4.9 0.3 11.2 1.6 2.3 2 0 0 2 2 2 0 Mediator complex subunit 28 WXG100 PF06013.12 EKX36668.1 - 0.86 9.9 10.5 1.1 9.6 0.2 3.8 3 1 0 3 3 3 0 Proteins of 100 residues with WXG GIT_CC PF16559.5 EKX36668.1 - 4.7 7.2 13.7 4.9 7.1 1.0 4.3 3 2 2 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor Herpes_UL14 PF03580.14 EKX36668.1 - 5.1 7.3 10.9 0.2 11.9 2.4 2.5 3 0 0 3 3 3 0 Herpesvirus UL14-like protein APG6_N PF17675.1 EKX36668.1 - 7.5 7.1 21.6 1.3 9.6 1.3 3.4 3 0 0 3 3 3 0 Apg6 coiled-coil region Mid1 PF12929.7 EKX36670.1 - 2.1e-06 27.2 22.4 0.00037 19.8 11.2 2.4 2 0 0 2 2 2 2 Stretch-activated Ca2+-permeable channel component DUF3732 PF12532.8 EKX36670.1 - 0.11 12.0 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3732) HrpB7 PF09486.10 EKX36671.1 - 0.033 14.6 0.5 0.033 14.6 0.5 5.5 4 2 3 7 7 7 0 Bacterial type III secretion protein (HrpB7) DUF2443 PF10398.9 EKX36671.1 - 1.1 9.4 4.3 16 5.6 0.1 4.1 3 2 1 4 4 4 0 Protein of unknown function (DUF2443) MAD PF05557.13 EKX36671.1 - 2.1 6.6 47.6 6 5.1 33.9 2.2 1 1 1 2 2 2 0 Mitotic checkpoint protein NPV_P10 PF05531.12 EKX36671.1 - 2.1 8.8 15.1 1 9.9 0.1 4.7 3 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein Lectin_N PF03954.14 EKX36671.1 - 3.4 7.4 16.4 2.3 8.0 4.6 4.0 4 0 0 4 4 4 0 Hepatic lectin, N-terminal domain BST2 PF16716.5 EKX36671.1 - 3.4 8.3 28.7 2.5 8.7 2.6 4.4 1 1 1 3 3 3 0 Bone marrow stromal antigen 2 CALCOCO1 PF07888.11 EKX36671.1 - 4 6.2 45.4 6.2 5.6 27.4 3.0 2 1 1 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like FUSC PF04632.12 EKX36671.1 - 5.7 5.4 20.1 3.1 6.2 7.4 2.2 1 1 1 2 2 2 0 Fusaric acid resistance protein family APG6_N PF17675.1 EKX36671.1 - 6.1 7.4 50.4 0.19 12.2 10.5 4.7 2 1 2 4 4 4 0 Apg6 coiled-coil region ThiS PF02597.20 EKX36671.1 - 6.3 7.5 11.1 11 6.7 0.3 4.2 4 2 0 4 4 4 0 ThiS family PDZ_2 PF13180.6 EKX36672.1 - 4.3e-17 62.2 0.3 3.5e-08 33.7 0.3 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EKX36672.1 - 9.6e-15 54.2 3.8 1.1e-10 41.2 0.1 3.1 2 1 0 2 2 2 2 PDZ domain PDZ PF00595.24 EKX36672.1 - 5.8e-13 49.0 1.4 1.6e-05 25.1 0.0 2.7 3 0 0 3 3 3 2 PDZ domain Tricorn_PDZ PF14685.6 EKX36672.1 - 1.6e-05 24.7 0.7 0.19 11.7 0.0 2.5 2 0 0 2 2 2 2 Tricorn protease PDZ domain LRRFIP PF09738.9 EKX36672.1 - 0.0094 15.5 3.9 0.0094 15.5 3.9 1.8 2 0 0 2 2 2 1 LRRFIP family GRASP55_65 PF04495.14 EKX36672.1 - 0.1 12.9 0.0 15 5.9 0.0 2.4 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain Phe_tRNA-synt_N PF02912.18 EKX36672.1 - 3.2 7.8 6.0 3.1 7.8 3.6 2.2 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain tRNA_Me_trans PF03054.16 EKX36673.1 - 0.13 11.0 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 tRNA methyl transferase TMEM65 PF10507.9 EKX36674.1 - 1.6e-33 114.9 2.5 2.6e-33 114.2 2.5 1.3 1 0 0 1 1 1 1 Transmembrane protein 65 MOLO1 PF17175.4 EKX36674.1 - 1.5e-08 34.8 0.1 8.9e-08 32.3 0.1 2.0 1 1 0 1 1 1 1 Modulator of levamisole receptor-1 Cons_hypoth698 PF03601.14 EKX36674.1 - 0.0079 15.1 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 698 Pkinase PF00069.25 EKX36676.1 - 4.7e-09 36.0 0.0 2.8e-08 33.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX36676.1 - 6.2e-06 25.7 0.1 3.1e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase MFS_1 PF07690.16 EKX36677.1 - 4.4e-23 81.8 34.3 3.5e-20 72.2 21.3 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EKX36677.1 - 9.3e-08 31.3 18.8 2.9e-05 23.1 6.1 2.9 2 1 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 EKX36677.1 - 9.6e-05 21.4 3.8 0.085 11.7 0.5 3.2 2 2 0 2 2 2 2 MFS_1 like family RecT PF03837.14 EKX36677.1 - 0.63 9.5 2.9 1 8.8 2.9 1.2 1 0 0 1 1 1 0 RecT family LacY_symp PF01306.19 EKX36677.1 - 0.85 8.3 9.0 2.2 6.9 0.6 3.5 2 2 2 4 4 4 0 LacY proton/sugar symporter SNAP PF14938.6 EKX36678.1 - 1.9e-103 345.7 17.2 2.2e-103 345.6 17.2 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 EKX36678.1 - 1.7e-06 28.3 5.5 6.2 7.7 0.0 6.7 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX36678.1 - 0.00019 21.2 5.2 5.7 7.2 0.0 5.6 4 2 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX36678.1 - 0.0018 18.7 3.9 12 6.5 0.1 4.2 2 2 1 3 3 3 0 Tetratricopeptide repeat DHR-2 PF06920.13 EKX36678.1 - 0.002 16.9 0.3 0.13 10.9 0.0 2.2 1 1 1 2 2 2 1 Dock homology region 2 TPR_2 PF07719.17 EKX36678.1 - 0.0032 17.5 16.7 9.7 6.6 0.1 7.3 6 1 2 8 8 8 1 Tetratricopeptide repeat RPN7 PF10602.9 EKX36678.1 - 0.0099 15.6 1.8 0.048 13.4 0.2 2.2 1 1 1 2 2 2 1 26S proteasome subunit RPN7 TPR_MalT PF17874.1 EKX36678.1 - 0.042 13.2 0.7 0.067 12.6 0.7 1.4 1 0 0 1 1 1 0 MalT-like TPR region TPR_16 PF13432.6 EKX36678.1 - 0.064 13.9 8.6 17 6.2 2.6 4.2 2 1 2 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX36678.1 - 0.069 13.4 3.8 0.81 10.0 0.0 3.8 1 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EKX36678.1 - 0.084 12.6 5.6 41 4.0 0.0 5.0 5 0 0 5 5 5 0 TPR repeat TPR_12 PF13424.6 EKX36678.1 - 0.17 12.2 10.6 25 5.2 0.1 4.9 2 2 2 4 4 4 0 Tetratricopeptide repeat DUF410 PF04190.13 EKX36678.1 - 0.19 11.5 5.2 0.65 9.7 5.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF410) MIT PF04212.18 EKX36678.1 - 0.19 11.8 13.7 4.2 7.5 0.1 5.5 5 1 2 7 7 7 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 EKX36678.1 - 0.36 10.7 14.6 11 6.1 0.1 6.4 5 2 2 8 8 8 0 Tetratricopeptide repeat NSF PF02071.20 EKX36678.1 - 2 9.6 16.3 49 5.4 0.1 6.1 6 0 0 6 6 5 0 Aromatic-di-Alanine (AdAR) repeat LRR_6 PF13516.6 EKX36680.1 - 1.7e-40 133.7 17.3 4.5e-06 26.3 0.1 9.1 9 0 0 9 9 9 7 Leucine Rich repeat LRR_4 PF12799.7 EKX36680.1 - 1.5e-06 28.4 3.0 8.2 7.0 0.1 5.6 2 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX36680.1 - 0.0092 16.4 0.0 1.9e+02 3.3 0.0 5.6 6 0 0 6 6 6 0 Leucine Rich Repeat Collagen_bind_2 PF12904.7 EKX36680.1 - 0.2 11.7 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative collagen-binding domain of a collagenase SET PF00856.28 EKX36682.1 - 2.1e-06 28.3 0.0 5e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 SET domain FlxA PF14282.6 EKX36682.1 - 3.9 7.5 6.6 0.67 10.0 0.6 2.1 2 0 0 2 2 2 0 FlxA-like protein HD PF01966.22 EKX36683.1 - 1.7e-10 41.2 0.1 6.8e-10 39.2 0.0 2.1 2 1 0 2 2 2 1 HD domain PDEase_I PF00233.19 EKX36683.1 - 0.016 14.9 0.9 0.04 13.6 0.1 1.9 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase DUF4667 PF15700.5 EKX36684.1 - 0.017 15.2 5.9 0.032 14.3 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) FAM91_C PF14648.6 EKX36684.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 FAM91 C-terminus Apt1 PF10351.9 EKX36684.1 - 0.3 9.9 1.2 0.5 9.2 1.2 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Secretin_N_2 PF07655.13 EKX36684.1 - 2.6 8.7 15.2 6.5 7.4 15.2 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Macoilin PF09726.9 EKX36684.1 - 4.7 5.6 6.5 6.9 5.1 6.5 1.1 1 0 0 1 1 1 0 Macoilin family SapB_1 PF05184.15 EKX36685.1 - 4.5e-10 39.3 28.3 0.00014 21.8 2.2 6.0 6 0 0 6 6 6 3 Saposin-like type B, region 1 SapB_2 PF03489.17 EKX36685.1 - 5.7e-08 32.7 18.8 0.0057 16.7 0.5 5.9 5 0 0 5 5 5 2 Saposin-like type B, region 2 GerD PF17898.1 EKX36685.1 - 0.02 14.8 0.2 9.8 6.2 0.0 3.2 3 0 0 3 3 3 0 Spore germination GerD central core domain DUF445 PF04286.12 EKX36685.1 - 0.025 14.4 0.4 0.11 12.2 0.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF445) YmgD PF16456.5 EKX36685.1 - 0.06 13.4 7.6 0.17 11.9 0.7 3.2 3 0 0 3 3 3 0 YmgD protein DUF3802 PF12290.8 EKX36685.1 - 0.39 11.3 4.4 37 4.9 0.0 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF3802) DUF4359 PF14271.6 EKX36685.1 - 0.53 11.1 16.3 19 6.1 0.1 5.6 2 1 3 6 6 6 0 Domain of unknown function (DUF4359) zf-AD PF07776.15 EKX36685.1 - 1 9.7 0.0 1 9.7 0.0 4.2 5 0 0 5 5 5 0 Zinc-finger associated domain (zf-AD) P2X_receptor PF00864.19 EKX36686.1 - 7.2e-08 31.9 0.0 9.4e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 ATP P2X receptor Pkinase PF00069.25 EKX36688.1 - 5.9e-79 265.1 0.0 6.7e-79 265.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX36688.1 - 6.9e-33 114.0 0.0 1.1e-32 113.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EKX36688.1 - 1.3e-05 24.3 0.1 0.00024 20.2 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EKX36688.1 - 0.01 15.8 0.1 0.016 15.1 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EKX36688.1 - 0.011 14.8 0.1 0.016 14.3 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 EKX36688.1 - 0.019 14.3 0.0 0.059 12.7 0.0 1.7 1 1 0 2 2 2 0 Kinase-like Kdo PF06293.14 EKX36688.1 - 0.036 13.4 0.4 0.092 12.1 0.2 1.7 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family BTB_2 PF02214.22 EKX36689.1 - 1e-05 25.8 0.0 2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF1905 PF08922.11 EKX36689.1 - 0.062 13.4 0.0 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1905) CheZ PF04344.13 EKX36691.1 - 0.041 13.8 0.0 0.042 13.8 0.0 1.0 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ AAA_6 PF12774.7 EKX36692.1 - 1.2e-154 514.1 0.0 1.2e-153 510.9 0.0 2.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EKX36692.1 - 1.7e-127 425.8 14.8 1.7e-127 425.8 14.8 4.8 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EKX36692.1 - 1.8e-111 371.7 0.6 6.3e-111 369.9 0.0 2.4 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EKX36692.1 - 4.6e-96 320.2 4.6 1.4e-95 318.6 0.2 3.8 3 1 1 4 4 4 1 ATP-binding dynein motor region Dynein_C PF18199.1 EKX36692.1 - 2.3e-93 312.8 1.0 6.2e-91 304.8 0.0 3.7 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 EKX36692.1 - 1.5e-64 216.8 0.4 6.6e-61 205.0 0.0 3.7 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EKX36692.1 - 5.7e-56 188.9 0.2 1.3e-55 187.7 0.2 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EKX36692.1 - 1.8e-45 153.9 0.0 1.5e-41 141.2 0.0 4.0 3 0 0 3 3 3 2 Dynein heavy chain region D6 P-loop domain MT PF12777.7 EKX36692.1 - 1.1e-44 152.9 16.2 3.2e-44 151.4 16.2 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 EKX36692.1 - 1.9e-28 99.1 0.3 1.8e-27 96.0 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EKX36692.1 - 5.6e-20 71.4 0.0 3e-19 69.1 0.0 2.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EKX36692.1 - 2.9e-17 63.0 0.0 3.5e-05 23.8 0.0 7.0 6 1 0 6 6 5 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EKX36692.1 - 2.5e-09 37.7 0.1 0.0022 18.4 0.0 5.9 4 1 1 5 5 5 1 AAA ATPase domain AAA_22 PF13401.6 EKX36692.1 - 3.7e-07 30.5 0.3 1 9.7 0.0 5.9 5 0 0 5 5 5 1 AAA domain AAA PF00004.29 EKX36692.1 - 5.3e-07 30.1 4.1 0.13 12.7 0.0 5.6 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EKX36692.1 - 5.5e-06 27.0 0.4 0.89 10.1 0.0 4.6 4 0 0 4 4 3 2 AAA domain RNA_helicase PF00910.22 EKX36692.1 - 0.0061 16.9 0.2 66 3.9 0.0 4.9 4 0 0 4 4 4 0 RNA helicase AAA_33 PF13671.6 EKX36692.1 - 0.017 15.3 0.2 4 7.6 0.0 3.9 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 EKX36692.1 - 0.11 12.2 7.0 20 4.9 0.1 5.0 5 0 0 5 5 5 0 AAA domain Sigma54_activat PF00158.26 EKX36692.1 - 0.11 12.2 0.4 4 7.1 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_25 PF13481.6 EKX36692.1 - 0.16 11.5 1.0 5.7 6.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 EKX36692.1 - 0.29 11.3 3.7 5.1 7.3 0.0 3.2 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase CbiA PF01656.23 EKX36692.1 - 0.37 10.8 4.5 11 6.2 0.1 4.3 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain Spc7 PF08317.11 EKX36692.1 - 5 5.9 40.4 0.06 12.2 7.4 4.1 4 0 0 4 4 4 0 Spc7 kinetochore protein Zn_clus PF00172.18 EKX36694.1 - 4.4e-05 23.5 9.7 4.4e-05 23.5 9.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S8_N PF16361.5 EKX36694.1 - 0.1 13.1 0.0 0.24 11.9 0.0 1.6 2 0 0 2 2 2 0 N-terminal of Subtilase family VAPB_antitox PF02697.14 EKX36694.1 - 0.17 12.7 2.8 9.6 7.1 0.0 3.7 3 1 0 3 3 3 0 Putative antitoxin Ank_2 PF12796.7 EKX36695.1 - 2.8e-13 50.2 0.0 1.1e-08 35.6 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX36695.1 - 3.6e-10 39.2 0.0 0.002 18.5 0.0 5.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 EKX36695.1 - 3.6e-10 40.2 0.3 1.3e-06 28.9 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX36695.1 - 2.6e-06 27.6 0.0 0.04 14.3 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX36695.1 - 0.00028 21.2 0.0 0.12 12.9 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat Ion_trans PF00520.31 EKX36695.1 - 0.013 14.7 26.1 0.031 13.5 25.9 1.7 1 1 0 1 1 1 0 Ion transport protein BAF PF02961.14 EKX36695.1 - 0.053 14.0 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Barrier to autointegration factor Pertactin PF03212.14 EKX36695.1 - 0.069 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Pertactin Alpha_adaptin_C PF02296.16 EKX36695.1 - 0.13 12.5 0.0 1.2 9.4 0.0 2.2 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain zf-CCHC_2 PF13696.6 EKX36696.1 - 2.2e-05 24.1 4.4 2.2e-05 24.1 4.4 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 EKX36696.1 - 0.00065 19.7 1.0 0.0013 18.7 1.0 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 EKX36696.1 - 0.01 15.5 1.9 0.025 14.3 1.9 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DWNN PF08783.11 EKX36696.1 - 0.031 14.6 0.0 0.079 13.3 0.0 1.8 1 0 0 1 1 1 0 DWNN domain U-box PF04564.15 EKX36696.1 - 0.047 13.9 1.7 0.062 13.5 0.1 2.1 3 0 0 3 3 3 0 U-box domain CH_2 PF06294.11 EKX36697.1 - 5.1e-33 113.1 0.6 1e-32 112.1 0.1 1.8 2 0 0 2 2 2 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 EKX36697.1 - 3.3e-14 52.5 0.0 5.6e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.31 EKX36697.1 - 4e-06 27.0 0.9 1.9e-05 24.8 0.1 2.0 2 0 0 2 2 2 1 Calponin homology (CH) domain DUF641 PF04859.12 EKX36697.1 - 0.0052 17.1 3.9 0.0068 16.7 3.2 1.8 1 1 0 1 1 1 1 Plant protein of unknown function (DUF641) FAM76 PF16046.5 EKX36697.1 - 0.019 14.3 5.0 0.025 13.9 5.0 1.1 1 0 0 1 1 1 0 FAM76 protein PKcGMP_CC PF16808.5 EKX36697.1 - 0.028 14.3 9.0 0.26 11.2 1.5 3.4 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Fib_alpha PF08702.10 EKX36697.1 - 0.048 13.8 6.4 0.16 12.2 6.3 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 EKX36697.1 - 0.11 13.0 4.8 0.073 13.6 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 ATG16 PF08614.11 EKX36697.1 - 0.17 12.1 7.8 0.29 11.3 7.8 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 EKX36697.1 - 0.49 10.4 4.6 0.27 11.3 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) AKNA PF12443.8 EKX36697.1 - 1.5 9.5 5.8 0.45 11.2 2.0 2.1 1 1 0 1 1 1 0 AT-hook-containing transcription factor TMF_DNA_bd PF12329.8 EKX36697.1 - 2.9 8.0 10.4 0.66 10.0 4.8 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding IRF-2BP1_2 PF11261.8 EKX36698.1 - 0.093 12.3 0.2 0.15 11.6 0.2 1.3 1 0 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger Pkinase PF00069.25 EKX36699.1 - 0.00069 19.1 0.0 0.00069 19.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain BMFP PF04380.13 EKX36705.1 - 0.027 15.0 0.2 7.8 7.1 0.0 2.4 2 1 1 3 3 3 0 Membrane fusogenic activity Abhydrolase_2 PF02230.16 EKX36705.1 - 0.094 12.5 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Glyco_transf_8 PF01501.20 EKX36708.1 - 0.00026 20.7 0.1 0.0039 16.8 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_8 PF01501.20 EKX36709.1 - 9.8e-10 38.4 0.0 2.7e-09 36.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 PDDEXK_3 PF13366.6 EKX36710.1 - 2e-09 37.8 0.0 3.5e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily RPW8 PF05659.11 EKX36711.1 - 0.07 12.8 1.6 0.18 11.5 1.6 1.6 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 EMP24_GP25L PF01105.24 EKX36711.1 - 0.1 12.5 3.6 0.16 11.9 3.6 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF45 PF01863.17 EKX36711.1 - 3.1 7.8 9.4 1.5 8.8 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF45 DUF5320 PF17253.2 EKX36711.1 - 4.7 8.3 5.2 2.2 9.4 0.5 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Pkinase PF00069.25 EKX36712.1 - 0.0037 16.7 0.0 0.021 14.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX36712.1 - 0.039 13.2 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DUF4852 PF16144.5 EKX36713.1 - 0.053 13.6 0.0 0.12 12.5 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4852) DUF382 PF04037.13 EKX36713.1 - 0.059 13.5 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF382) DUF2213 PF09979.9 EKX36716.1 - 0.0066 16.4 0.0 0.009 16.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2213) DUF1694 PF07997.11 EKX36718.1 - 0.069 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1694) HXXEE PF13787.6 EKX36718.1 - 1.9 9.4 4.9 4.8 8.0 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function with HXXEE motif DUF5384 PF17358.2 EKX36721.1 - 0.0042 17.1 2.6 0.0091 16.0 2.6 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5384) Pox_A3L PF05288.11 EKX36721.1 - 0.36 10.9 2.7 5.9 7.0 0.0 3.4 3 1 0 3 3 3 0 Poxvirus A3L Protein HTHP PF11534.8 EKX36722.1 - 0.4 11.1 1.6 46 4.5 0.0 3.7 1 1 4 5 5 5 0 Hexameric tyrosine-coordinated heme protein (HTHP) Spc7 PF08317.11 EKX36723.1 - 0.032 13.1 12.6 0.047 12.6 12.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 EKX36723.1 - 0.039 14.1 11.1 0.059 13.5 11.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Ssu72 PF04722.13 EKX36723.1 - 0.15 11.6 1.5 0.19 11.3 0.4 1.7 2 0 0 2 2 2 0 Ssu72-like protein FAM76 PF16046.5 EKX36723.1 - 0.5 9.7 8.8 0.77 9.0 8.8 1.2 1 0 0 1 1 1 0 FAM76 protein PEP-utilisers_N PF05524.13 EKX36723.1 - 1.1 9.5 5.9 1.4 9.1 4.8 1.8 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal GrpE PF01025.19 EKX36723.1 - 1.1 8.8 16.5 0.14 11.8 4.0 2.9 2 1 1 3 3 3 0 GrpE FapA PF03961.13 EKX36723.1 - 2.4 6.6 10.2 3.6 6.1 10.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF702 PF05142.12 EKX36723.1 - 3.1 8.3 6.0 5.4 7.5 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) zf-C4H2 PF10146.9 EKX36723.1 - 6 7.1 12.1 9.1 6.5 12.1 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein Ephrin_rec_like PF07699.13 EKX36724.1 - 0.00052 19.7 1.5 0.0012 18.5 1.5 1.6 1 0 0 1 1 1 1 Putative ephrin-receptor like MULE PF10551.9 EKX36725.1 - 2.4e-06 27.8 0.0 3.2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 EKX36725.1 - 0.018 14.8 0.0 0.019 14.7 0.0 1.1 1 0 0 1 1 1 0 Transposase Transposase_mut PF00872.18 EKX36725.1 - 0.051 12.4 0.0 0.051 12.4 0.0 1.0 1 0 0 1 1 1 0 Transposase, Mutator family Phage_int_SAM_4 PF13495.6 EKX36726.1 - 0.00057 20.3 0.2 0.18 12.3 0.0 2.8 3 0 0 3 3 3 2 Phage integrase, N-terminal SAM-like domain Sec1 PF00995.23 EKX36727.1 - 4.4e-62 211.1 0.0 5.2e-62 210.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Bestrophin PF01062.21 EKX36728.1 - 1.1e-23 84.1 0.4 1.5e-23 83.6 0.4 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Macoilin PF09726.9 EKX36728.1 - 0.23 10.0 0.2 0.35 9.4 0.2 1.2 1 0 0 1 1 1 0 Macoilin family TIM PF00121.18 EKX36730.1 - 1.6e-82 276.5 0.0 1.8e-82 276.4 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DUF521 PF04412.13 EKX36730.1 - 0.018 13.7 0.0 0.025 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF521) IL6 PF00489.17 EKX36730.1 - 0.09 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family PDZ_6 PF17820.1 EKX36734.1 - 1.9e-08 34.0 0.0 2.5e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX36734.1 - 1.1e-07 32.1 0.0 1.4e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX36734.1 - 1.4e-07 31.7 0.0 2.1e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX36734.1 - 0.041 13.9 0.0 0.069 13.1 0.0 1.4 1 1 0 1 1 1 0 Tricorn protease PDZ domain YcgR_2 PF12945.7 EKX36734.1 - 0.072 13.2 0.0 10 6.4 0.0 2.3 2 0 0 2 2 2 0 Flagellar protein YcgR DUF1860 PF08949.10 EKX36734.1 - 0.79 9.4 7.9 1.4 8.7 7.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1860) YL1 PF05764.13 EKX36735.1 - 3.1e-05 24.2 0.6 3.1e-05 24.2 0.6 2.3 2 0 0 2 2 2 1 YL1 nuclear protein CDC45 PF02724.14 EKX36735.1 - 0.0043 15.4 3.3 0.0078 14.6 3.3 1.3 1 0 0 1 1 1 1 CDC45-like protein CPSF100_C PF13299.6 EKX36735.1 - 0.064 13.4 0.4 0.064 13.4 0.4 1.9 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Radial_spoke PF04712.12 EKX36735.1 - 0.12 11.3 1.9 0.19 10.6 1.9 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein RRN3 PF05327.11 EKX36735.1 - 0.14 10.6 2.5 0.24 9.9 2.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nucleo_P87 PF07267.11 EKX36735.1 - 0.15 10.8 1.5 0.21 10.4 1.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FAM176 PF14851.6 EKX36735.1 - 0.36 10.5 5.9 0.99 9.1 5.9 1.7 1 0 0 1 1 1 0 FAM176 family SGT1 PF07093.11 EKX36735.1 - 0.83 8.0 4.9 0.18 10.2 1.5 1.7 2 0 0 2 2 2 0 SGT1 protein HA2 PF04408.23 EKX36735.1 - 0.95 9.8 3.9 0.61 10.4 1.2 2.0 2 0 0 2 2 2 0 Helicase associated domain (HA2) TFB6 PF17110.5 EKX36735.1 - 1.7 8.4 4.4 3.8 7.2 4.4 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Protocadherin PF08374.11 EKX36735.1 - 4.3 7.3 5.9 11 5.9 0.6 3.0 3 0 0 3 3 3 0 Protocadherin DUF2457 PF10446.9 EKX36735.1 - 5 6.2 15.3 9.5 5.2 15.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) THOC2_N PF16134.5 EKX36735.1 - 5 5.6 5.6 9.3 4.7 5.6 1.3 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Spt5_N PF11942.8 EKX36735.1 - 8.6 7.4 18.2 1.1 10.3 12.7 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal PALP PF00291.25 EKX36736.1 - 1.4e-73 247.9 0.2 1.7e-73 247.6 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EKX36736.1 - 0.003 16.9 0.0 0.0045 16.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family RWP-RK PF02042.15 EKX36737.1 - 3.8e-15 55.6 0.0 7.2e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain HTH_6 PF01418.17 EKX36737.1 - 0.00056 19.8 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family HTH_28 PF13518.6 EKX36737.1 - 0.0014 18.7 0.1 0.0049 17.0 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 EKX36737.1 - 0.016 15.0 0.1 0.046 13.5 0.1 1.7 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 EKX36737.1 - 0.017 14.5 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4_2 PF08281.12 EKX36737.1 - 0.019 14.6 0.0 0.04 13.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_8 PF02954.19 EKX36737.1 - 0.035 13.9 0.4 0.099 12.5 0.3 1.8 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family HTH_31 PF13560.6 EKX36737.1 - 0.054 13.9 0.1 0.095 13.1 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 EKX36737.1 - 0.071 13.4 0.7 0.33 11.3 0.1 2.3 2 1 0 2 2 2 0 Transposase HTH_AraC PF00165.23 EKX36737.1 - 0.13 12.4 0.0 0.53 10.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_17 PF12728.7 EKX36737.1 - 0.14 12.3 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain RWP-RK PF02042.15 EKX36738.1 - 2.9e-07 30.3 0.1 7e-07 29.1 0.0 1.7 2 0 0 2 2 2 1 RWP-RK domain RWP-RK PF02042.15 EKX36739.1 - 6.8e-14 51.6 0.1 9.9e-14 51.1 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX36739.1 - 0.02 14.7 0.2 1 9.2 0.1 2.8 2 1 1 3 3 3 0 Bacterial regulatory protein, Fis family HTH_28 PF13518.6 EKX36739.1 - 0.033 14.3 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 EKX36739.1 - 0.079 12.5 0.0 0.38 10.4 0.0 2.0 1 1 1 2 2 2 0 Winged helix-turn-helix DNA-binding RWP-RK PF02042.15 EKX36740.1 - 3.3e-13 49.4 0.0 6.6e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain DUF3637 PF12337.8 EKX36740.1 - 0.1 12.9 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3637) BAH PF01426.18 EKX36741.1 - 2.8e-05 24.0 0.0 0.0003 20.6 0.0 2.7 2 1 0 2 2 2 1 BAH domain TUDOR_5 PF18359.1 EKX36741.1 - 3.4e-05 23.5 0.1 8.3e-05 22.2 0.1 1.7 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 Tudor_3 PF18115.1 EKX36741.1 - 0.00092 19.0 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Tudor_2 PF18104.1 EKX36741.1 - 0.029 14.1 0.2 0.19 11.4 0.0 2.5 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain SH3_15 PF18346.1 EKX36741.1 - 0.11 12.9 2.1 0.2 12.0 0.9 2.2 2 0 0 2 2 2 0 Mind bomb SH3 repeat domain DUF503 PF04456.12 EKX36741.1 - 2 8.3 4.9 0.82 9.6 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF503) Abhydrolase_6 PF12697.7 EKX36742.1 - 1.4e-10 42.2 0.0 2.1e-09 38.3 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EKX36742.1 - 2.4e-10 40.5 0.0 2.7e-09 37.1 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EKX36742.1 - 0.0011 18.3 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EKX36742.1 - 0.0087 15.8 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Siah-Interact_N PF09032.11 EKX36743.1 - 0.00018 21.8 0.3 0.00038 20.7 0.3 1.5 1 0 0 1 1 1 1 Siah interacting protein, N terminal FANCL_C PF11793.8 EKX36743.1 - 0.075 13.2 0.4 0.23 11.6 0.4 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain Beta_helix PF13229.6 EKX36745.1 - 9.2e-06 25.6 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Right handed beta helix region DUF3657 PF12394.8 EKX36745.1 - 0.17 12.5 0.0 0.76 10.4 0.0 2.1 1 0 0 1 1 1 0 Protein FAM135 Tropomyosin_1 PF12718.7 EKX36746.1 - 0.0012 19.0 2.7 0.0016 18.6 2.7 1.1 1 0 0 1 1 1 1 Tropomyosin like Nup88 PF10168.9 EKX36746.1 - 0.007 14.2 1.8 0.0074 14.2 1.8 1.1 1 0 0 1 1 1 1 Nuclear pore component Atg14 PF10186.9 EKX36746.1 - 0.02 14.0 1.9 0.022 13.8 1.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 EKX36746.1 - 0.18 12.0 0.2 0.18 12.0 0.2 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Phage_Gp23 PF10669.9 EKX36746.1 - 0.26 11.6 4.0 0.34 11.2 4.0 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) FlaC_arch PF05377.11 EKX36746.1 - 0.32 11.4 3.8 0.26 11.7 0.5 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Shugoshin_N PF07558.11 EKX36746.1 - 2.2 8.2 7.8 0.52 10.2 3.2 2.2 2 1 0 2 2 2 0 Shugoshin N-terminal coiled-coil region CxxCxxCC PF03692.15 EKX36747.1 - 8.6e-08 32.8 6.6 2.1e-07 31.5 6.6 1.7 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain Phage_terminase PF10668.9 EKX36748.1 - 0.022 14.8 0.2 0.039 14.0 0.2 1.4 1 0 0 1 1 1 0 Phage terminase small subunit FGGY_N PF00370.21 EKX36749.1 - 6.1e-73 245.4 0.0 8.6e-73 244.9 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EKX36749.1 - 5.7e-58 195.9 2.7 8.7e-58 195.3 2.2 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 EKX36749.1 - 0.0009 18.8 0.4 0.045 13.2 0.0 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family GDP_Man_Dehyd PF16363.5 EKX36750.1 - 1.9e-43 149.2 0.0 3.8e-43 148.2 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EKX36750.1 - 1.1e-36 126.5 0.0 1.5e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EKX36750.1 - 1.9e-09 37.0 0.1 8.5e-09 34.9 0.1 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EKX36750.1 - 6.4e-09 35.2 0.0 9e-09 34.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EKX36750.1 - 2.1e-07 30.3 0.0 4.4e-06 26.0 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EKX36750.1 - 0.083 12.0 0.1 6.4 5.9 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein Phosducin PF02114.16 EKX36751.1 - 5.2e-15 55.1 0.3 6.4e-15 54.8 0.3 1.1 1 0 0 1 1 1 1 Phosducin DUF1722 PF08349.11 EKX36751.1 - 7.1e-05 23.1 0.9 0.00024 21.4 0.2 2.1 2 1 1 3 3 3 1 Protein of unknown function (DUF1722) DUF4698 PF15769.5 EKX36751.1 - 0.0035 16.5 1.8 0.022 13.8 0.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4698) Virulence_fact PF13769.6 EKX36751.1 - 0.74 10.1 5.6 0.5 10.6 2.7 2.2 2 1 1 3 3 3 0 Virulence factor Ribosomal_L27 PF01016.19 EKX36752.1 - 5.2e-34 116.1 1.5 8.2e-34 115.5 1.5 1.3 1 0 0 1 1 1 1 Ribosomal L27 protein Tim17 PF02466.19 EKX36753.1 - 0.00087 19.6 2.4 0.0013 19.1 1.8 1.7 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF1614 PF07758.11 EKX36753.1 - 0.033 14.2 2.3 0.049 13.6 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1614) Polysacc_synt_C PF14667.6 EKX36753.1 - 0.18 11.9 5.5 2.4 8.2 5.5 2.0 1 1 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain TraT PF05818.12 EKX36753.1 - 2.2 7.9 5.8 1.9 8.2 1.3 2.1 1 1 1 2 2 2 0 Enterobacterial TraT complement resistance protein Kinesin PF00225.23 EKX36754.1 - 3.4e-49 167.6 0.0 4.7e-28 98.1 0.0 2.1 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 EKX36754.1 - 1.8e-15 57.2 0.0 2.9e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding SapB_2 PF03489.17 EKX36754.1 - 0.027 14.6 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 Saposin-like type B, region 2 RWP-RK PF02042.15 EKX36755.1 - 1.1e-13 50.9 0.0 1.8e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX36755.1 - 0.091 12.6 0.6 0.69 9.8 0.5 2.1 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family Solute_trans_a PF03619.16 EKX36757.1 - 0.00019 21.0 9.4 0.00044 19.9 9.4 1.6 1 1 0 1 1 1 1 Organic solute transporter Ostalpha tRNA-synt_His PF13393.6 EKX36759.1 - 5.8e-41 140.8 0.0 8.2e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 EKX36759.1 - 6.8e-06 26.2 0.0 8.3e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 EKX36759.1 - 0.004 16.7 0.0 0.0097 15.4 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Pex2_Pex12 PF04757.14 EKX36760.1 - 5.2e-29 101.4 0.0 6.5e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region PDZ_6 PF17820.1 EKX36761.1 - 2.6e-05 24.0 0.0 0.0001 22.1 0.0 1.9 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 EKX36761.1 - 0.0016 18.3 0.0 0.0057 16.6 0.0 1.8 2 0 0 2 2 2 1 Tricorn protease PDZ domain Fib_alpha PF08702.10 EKX36762.1 - 0.55 10.4 14.4 0.47 10.6 0.9 3.2 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family ALMT PF11744.8 EKX36763.1 - 4.2 6.1 10.9 28 3.4 0.0 2.4 2 0 0 2 2 2 0 Aluminium activated malate transporter PTS_2-RNA PF01885.16 EKX36764.1 - 3.6e-56 190.1 0.1 4.1e-56 189.9 0.1 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family TPT PF03151.16 EKX36765.1 - 5.7e-29 101.4 16.7 6.9e-29 101.1 16.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EKX36765.1 - 2.5e-14 53.6 29.8 4.1e-07 30.3 6.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family PAS_9 PF13426.7 EKX36766.1 - 1.7e-06 28.2 0.0 6.3e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 PAS domain His_Phos_1 PF00300.22 EKX36767.1 - 3.3e-45 154.2 0.2 3e-35 121.7 0.1 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 EKX36767.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Peptidase_S8 PF00082.22 EKX36768.1 - 1.3e-16 60.7 0.0 1.9e-15 56.9 0.0 2.4 2 0 0 2 2 2 1 Subtilase family Jak1_Phl PF17887.1 EKX36768.1 - 0.011 15.7 0.1 0.021 14.8 0.1 1.4 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain DUF4448 PF14610.6 EKX36768.1 - 0.087 12.6 0.1 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Crp PF00325.20 EKX36768.1 - 0.21 11.3 0.2 0.63 9.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family LRR_8 PF13855.6 EKX36769.1 - 1.9e-16 59.6 0.7 2.2e-14 52.9 0.6 3.5 3 1 0 3 3 3 2 Leucine rich repeat LRR_5 PF13306.6 EKX36769.1 - 5.2e-08 32.9 0.0 5.2e-08 32.9 0.0 2.6 1 1 1 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 EKX36769.1 - 8.7e-05 22.8 1.7 0.00074 19.9 0.4 4.2 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) Tmemb_cc2 PF10267.9 EKX36769.1 - 0.062 12.4 7.3 0.07 12.3 7.3 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein LRR_1 PF00560.33 EKX36769.1 - 0.097 13.3 0.1 0.097 13.3 0.1 5.6 4 1 0 4 4 4 0 Leucine Rich Repeat DUF4207 PF13904.6 EKX36769.1 - 0.54 9.9 7.4 0.82 9.3 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) CC190 PF15768.5 EKX36769.1 - 2.1 8.3 7.4 2.7 8.0 7.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 Menin PF05053.13 EKX36769.1 - 3.1 6.0 10.3 3.8 5.7 10.3 1.1 1 0 0 1 1 1 0 Menin SprA-related PF12118.8 EKX36769.1 - 3.2 6.8 19.8 4.1 6.4 19.8 1.1 1 0 0 1 1 1 0 SprA-related family PAC2 PF09754.9 EKX36771.1 - 8e-12 45.6 0.0 9.1e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 PAC2 family ESCRT-II PF05871.12 EKX36771.1 - 0.0076 16.5 0.3 1.7 8.9 0.0 2.2 2 0 0 2 2 2 2 ESCRT-II complex subunit E1-E2_ATPase PF00122.20 EKX36772.1 - 1.3e-26 93.2 2.1 8.4e-26 90.6 0.1 2.9 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EKX36772.1 - 1.1e-13 51.9 0.8 0.00017 21.9 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EKX36772.1 - 7e-08 32.5 0.0 1.6e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EKX36772.1 - 1e-05 25.1 0.0 2.4e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF4736 PF15883.5 EKX36773.1 - 2.1 8.0 6.3 3.9 7.2 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) DUF3567 PF12091.8 EKX36775.1 - 0.038 14.1 0.0 0.063 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3567) Laminin_G_3 PF13385.6 EKX36776.1 - 1.5e-10 41.4 6.0 4.2e-10 40.0 6.0 1.7 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily tRNA-synt_2 PF00152.20 EKX36778.1 - 6.3e-79 265.3 0.1 2.9e-66 223.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EKX36778.1 - 1.9e-05 24.6 0.0 4.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EKX36778.1 - 0.03 13.8 0.0 0.25 10.8 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Desulfoferrodox PF01880.18 EKX36778.1 - 0.09 13.4 0.0 0.27 11.9 0.0 1.8 1 0 0 1 1 1 0 Desulfoferrodoxin DUF2203 PF09969.9 EKX36778.1 - 0.81 10.4 3.2 7 7.4 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) OmpH PF03938.14 EKX36778.1 - 3.5 8.0 9.4 2.6 8.4 0.5 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) PDZ_2 PF13180.6 EKX36780.1 - 6.3e-06 26.4 0.2 2.9e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 PDZ domain Pox_A_type_inc PF04508.12 EKX36780.1 - 0.0011 18.8 1.8 0.011 15.5 1.8 2.9 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat UPF0449 PF15136.6 EKX36780.1 - 0.0057 17.1 5.1 0.0057 17.1 5.1 4.5 2 2 2 4 4 4 1 Uncharacterised protein family UPF0449 HEAT_2 PF13646.6 EKX36782.1 - 5.8e-25 87.5 1.1 3.7e-14 52.9 0.0 2.9 3 0 0 3 3 3 2 HEAT repeats HEAT_PBS PF03130.16 EKX36782.1 - 8.3e-19 66.3 0.5 0.00022 21.6 0.0 5.2 5 0 0 5 5 5 4 PBS lyase HEAT-like repeat HEAT PF02985.22 EKX36782.1 - 3.1e-08 33.2 0.6 0.15 12.4 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 EKX36782.1 - 4.9e-05 23.7 2.9 0.44 11.1 0.0 4.1 4 1 1 5 5 5 2 HEAT-like repeat Arm PF00514.23 EKX36782.1 - 0.016 15.2 1.2 2.7 8.2 0.0 3.3 3 1 1 4 4 4 0 Armadillo/beta-catenin-like repeat TAF6_C PF07571.13 EKX36782.1 - 0.058 13.7 0.0 0.97 9.8 0.0 2.7 2 2 1 3 3 3 0 TAF6 C-terminal HEAT repeat domain ArfGap PF01412.18 EKX36783.1 - 2.3e-22 79.3 0.3 2.3e-22 79.3 0.3 2.2 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf PRIMA1 PF16101.5 EKX36783.1 - 0.045 13.8 9.7 0.1 12.6 9.7 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Tctex-1 PF03645.13 EKX36783.1 - 0.05 13.8 0.3 0.11 12.8 0.3 1.7 1 1 0 1 1 1 0 Tctex-1 family ParE_toxin PF05016.15 EKX36783.1 - 0.22 12.2 0.3 0.45 11.2 0.3 1.5 1 0 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE Med8 PF10232.9 EKX36783.1 - 0.24 10.9 5.4 0.34 10.5 5.4 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 DUF5308 PF17233.2 EKX36783.1 - 0.27 11.5 3.3 0.39 10.9 3.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5308) DUF4407 PF14362.6 EKX36783.1 - 3.9 6.7 5.8 5.2 6.3 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ion_trans PF00520.31 EKX36784.1 - 7.4e-42 143.3 11.2 8.8e-42 143.0 11.2 1.0 1 0 0 1 1 1 1 Ion transport protein DUF1421 PF07223.11 EKX36785.1 - 0.013 15.3 0.1 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 UBA-like domain (DUF1421) Mito_carr PF00153.27 EKX36786.1 - 2.1e-46 155.8 14.1 6.1e-20 71.0 0.4 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Glyco_transf_41 PF13844.6 EKX36787.1 - 7.3e-07 28.0 0.0 0.00028 19.5 0.0 2.1 1 1 0 2 2 2 2 Glycosyl transferase family 41 Glyco_transf_41 PF13844.6 EKX36788.1 - 2.4e-11 42.7 0.0 2.6e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 41 GST_N_3 PF13417.6 EKX36789.1 - 4.2e-17 62.3 0.0 1e-16 61.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EKX36789.1 - 4.3e-14 52.6 0.0 9.8e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EKX36789.1 - 9e-09 35.6 0.0 1.8e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EKX36789.1 - 1.4e-06 28.2 0.0 2.6e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EKX36789.1 - 2.4e-05 24.5 0.0 3.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_4 PF17172.4 EKX36789.1 - 0.013 16.2 0.0 0.15 12.8 0.0 2.4 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 EKX36789.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Profilin PF00235.19 EKX36790.1 - 1.4e-43 148.2 0.1 1.5e-43 148.0 0.1 1.0 1 0 0 1 1 1 1 Profilin SNARE_assoc PF09335.11 EKX36792.1 - 0.00045 20.7 1.6 0.00045 20.7 1.6 1.9 2 1 0 2 2 2 1 SNARE associated Golgi protein MoCF_biosynth PF00994.24 EKX36792.1 - 0.041 13.5 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 Probable molybdopterin binding domain PP2C PF00481.21 EKX36793.1 - 3.3e-30 105.6 0.1 2.1e-23 83.3 0.0 3.1 2 2 0 2 2 2 2 Protein phosphatase 2C PH PF00169.29 EKX36793.1 - 8.6e-08 32.6 0.1 1.8e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EKX36793.1 - 0.003 18.0 0.5 0.0068 16.8 0.5 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_16 PF17838.1 EKX36793.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 PH domain Ras PF00071.22 EKX36796.1 - 8.7e-40 136.0 0.0 1e-39 135.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EKX36796.1 - 6.6e-25 87.7 0.0 9.2e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EKX36796.1 - 9.6e-11 41.4 0.0 1.2e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EKX36796.1 - 2.5e-05 24.3 0.0 5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EKX36796.1 - 0.0021 17.6 0.3 0.015 14.8 0.1 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EKX36796.1 - 0.0052 16.2 0.0 0.0069 15.8 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region TniB PF05621.11 EKX36796.1 - 0.015 14.8 0.0 0.034 13.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 EKX36796.1 - 0.062 13.7 0.1 0.26 11.6 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain AlkA_N PF06029.11 EKX36796.1 - 0.082 13.2 1.0 2.6 8.3 0.6 2.7 2 1 0 2 2 2 0 AlkA N-terminal domain PduV-EutP PF10662.9 EKX36796.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 EKX36796.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B MFS_1 PF07690.16 EKX36797.1 - 6.2e-30 104.3 30.5 7.7e-30 104.0 30.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 EKX36797.1 - 7.1e-19 67.5 22.1 1e-06 27.4 0.5 3.9 1 1 3 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 EKX36797.1 - 4.6e-08 32.3 6.3 4.6e-08 32.3 6.3 2.3 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 EKX36797.1 - 1.4 7.2 11.2 1.9 6.8 11.2 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector Methyltransf_16 PF10294.9 EKX36799.1 - 1.2e-07 31.6 0.0 2.2e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EKX36799.1 - 0.12 12.2 0.1 0.96 9.3 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase domain GCV_T PF01571.21 EKX36801.1 - 7.3e-61 205.8 0.0 1.6e-60 204.7 0.0 1.6 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 EKX36801.1 - 3.2e-58 198.0 0.4 4.9e-58 197.4 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T_C PF08669.11 EKX36801.1 - 1.8e-17 63.0 0.1 1.8e-17 63.0 0.1 2.5 3 0 0 3 3 2 1 Glycine cleavage T-protein C-terminal barrel domain FAO_M PF16350.5 EKX36801.1 - 5.8e-10 39.4 0.0 1.1e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain Pyr_redox_2 PF07992.14 EKX36801.1 - 3.9e-06 26.3 0.2 8.7e-05 21.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EKX36801.1 - 6.9e-06 25.5 2.1 3.6e-05 23.2 2.1 1.9 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EKX36801.1 - 9.3e-05 21.7 3.1 0.00071 18.8 3.1 2.1 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EKX36801.1 - 9.4e-05 21.8 1.5 0.23 10.7 0.1 2.5 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.27 EKX36801.1 - 0.00016 22.1 2.1 0.0002 21.9 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EKX36801.1 - 0.00027 20.3 0.0 0.02 14.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SoxG PF04268.12 EKX36801.1 - 0.0022 18.2 0.0 0.0043 17.2 0.0 1.4 1 0 0 1 1 1 1 Sarcosine oxidase, gamma subunit family TrkA_N PF02254.18 EKX36801.1 - 0.003 17.8 0.0 0.0089 16.3 0.0 1.8 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.20 EKX36801.1 - 0.0069 16.4 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 EKX36801.1 - 0.0074 16.5 0.1 0.021 15.0 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EKX36801.1 - 0.018 14.4 0.9 0.047 13.0 0.9 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 EKX36801.1 - 0.022 14.4 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 EKX36801.1 - 0.028 13.7 0.1 0.081 12.2 0.1 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EKX36801.1 - 0.04 13.0 1.1 0.56 9.2 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A F420_oxidored PF03807.17 EKX36801.1 - 0.11 13.1 0.0 5.5 7.7 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Hema_HEFG PF02710.14 EKX36801.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.2 1 0 0 1 1 1 0 Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein NAD_binding_9 PF13454.6 EKX36801.1 - 0.23 11.5 1.2 6.3 6.8 0.0 3.4 4 0 0 4 4 4 0 FAD-NAD(P)-binding Sec31 PF11549.8 EKX36803.1 - 1.1 9.3 2.5 2.7 7.9 2.5 1.7 2 0 0 2 2 2 0 Protein transport protein SEC31 2OG-FeII_Oxy_3 PF13640.6 EKX36804.1 - 8.2e-07 29.8 0.0 1.3e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 EKX36804.1 - 0.063 13.5 0.1 0.41 10.9 0.1 2.2 1 1 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) YoeB_toxin PF06769.14 EKX36804.1 - 0.16 12.0 0.0 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 YoeB-like toxin of bacterial type II toxin-antitoxin system IBR PF01485.21 EKX36806.1 - 2.1e-07 31.1 10.4 2.1e-07 31.1 10.4 4.9 3 1 1 4 4 4 1 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EKX36806.1 - 0.0023 18.2 6.6 0.0023 18.2 6.6 4.3 3 1 0 3 3 3 1 Ring finger domain PHD PF00628.29 EKX36806.1 - 0.0032 17.3 2.3 0.0032 17.3 2.3 4.7 4 0 0 4 4 4 1 PHD-finger zf-HC5HC2H PF13771.6 EKX36806.1 - 0.34 11.2 26.5 0.096 12.9 3.1 3.8 3 0 0 3 3 3 0 PHD-like zinc-binding domain CorA PF01544.18 EKX36806.1 - 0.77 9.0 3.3 1.6 8.0 3.3 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein FA_desaturase PF00487.24 EKX36807.1 - 1.5e-32 113.4 4.5 1.5e-32 113.4 4.5 1.8 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 EKX36807.1 - 4.3e-07 30.0 0.0 8.5e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain UQ_con PF00179.26 EKX36809.1 - 6.4e-39 132.8 0.3 9.1e-39 132.3 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Homeobox_KN PF05920.11 EKX36810.1 - 6.4e-14 51.6 0.9 1.1e-13 50.8 0.9 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EKX36810.1 - 1.1e-05 25.2 2.6 1.1e-05 25.2 0.8 2.0 2 0 0 2 2 2 1 Homeodomain eIF-3c_N PF05470.12 EKX36811.1 - 0.00054 18.4 0.0 2.1 6.5 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SH2 PF00017.24 EKX36811.1 - 0.0033 17.5 0.0 0.0075 16.3 0.0 1.6 1 0 0 1 1 1 1 SH2 domain CDC45 PF02724.14 EKX36811.1 - 0.051 11.9 18.0 0.011 14.0 8.4 2.5 2 0 0 2 2 2 0 CDC45-like protein DUF4726 PF15855.5 EKX36811.1 - 0.14 12.4 0.5 0.57 10.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4726) SpoIIIAH PF12685.7 EKX36811.1 - 1.9 8.3 8.4 0.22 11.3 1.7 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein Protamine_3 PF08188.11 EKX36812.1 - 0.66 10.2 5.4 1.1 9.5 0.1 2.5 3 0 0 3 3 3 0 Spermatozal protamine family 7tm_7 PF08395.12 EKX36815.1 - 0.0016 17.7 0.0 0.0086 15.3 0.0 2.3 1 0 0 1 1 1 1 7tm Chemosensory receptor Guanylate_kin PF00625.21 EKX36816.1 - 7.1e-47 159.4 0.0 8.6e-47 159.2 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase RsgA_GTPase PF03193.16 EKX36816.1 - 6.4e-06 26.2 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 EKX36816.1 - 8.9e-05 23.0 0.1 0.00016 22.2 0.1 1.5 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EKX36816.1 - 0.00026 21.0 0.0 0.00031 20.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EKX36816.1 - 0.00062 20.2 0.2 0.00094 19.6 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 EKX36816.1 - 0.0063 16.4 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 EKX36816.1 - 0.0079 16.5 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EKX36816.1 - 0.0093 16.3 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.27 EKX36816.1 - 0.011 16.3 0.1 0.015 15.8 0.1 1.5 1 1 0 1 1 1 0 ABC transporter NTPase_1 PF03266.15 EKX36816.1 - 0.015 15.2 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.6 EKX36816.1 - 0.02 15.1 0.1 0.088 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EKX36816.1 - 0.067 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.6 EKX36816.1 - 0.1 13.0 0.1 0.25 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 EKX36816.1 - 0.15 11.3 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Septin ADK PF00406.22 EKX36817.1 - 6.9e-41 139.8 0.0 8.4e-41 139.6 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EKX36817.1 - 2.1e-36 125.4 0.0 2.4e-36 125.1 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EKX36817.1 - 5.4e-11 43.1 0.0 6.9e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EKX36817.1 - 9.7e-10 38.8 0.0 1.3e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EKX36817.1 - 0.0049 16.2 0.1 0.031 13.6 0.1 2.0 1 1 0 1 1 1 1 Zeta toxin Ploopntkinase3 PF18751.1 EKX36817.1 - 0.0049 16.8 0.0 0.0085 16.0 0.0 1.4 1 1 0 1 1 1 1 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 EKX36817.1 - 0.019 15.2 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 EKX36817.1 - 0.023 14.4 0.1 0.71 9.5 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase Hydin_ADK PF17213.3 EKX36817.1 - 0.053 13.8 0.0 0.96 9.7 0.0 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain IQ PF00612.27 EKX36818.1 - 0.00061 19.4 0.3 0.0017 17.9 0.3 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif Cob_adeno_trans PF01923.18 EKX36818.1 - 0.085 13.0 0.5 0.63 10.2 0.1 2.4 2 0 0 2 2 2 0 Cobalamin adenosyltransferase Occludin_ELL PF07303.13 EKX36818.1 - 1.2 9.9 6.8 0.42 11.3 0.6 3.3 3 0 0 3 3 3 0 Occludin homology domain Guanylate_kin PF00625.21 EKX36819.1 - 3.9e-15 56.0 0.0 5.8e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Guanylate kinase RIIa PF02197.17 EKX36819.1 - 1.9e-06 27.5 0.6 3.6e-06 26.5 0.6 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Zn_clus PF00172.18 EKX36820.1 - 1.1e-13 51.1 59.9 1.9e-05 24.6 10.3 3.9 4 1 0 4 4 4 3 Fungal Zn(2)-Cys(6) binuclear cluster domain RWP-RK PF02042.15 EKX36821.1 - 1.8e-14 53.5 0.1 8.6e-14 51.3 0.1 2.0 2 0 0 2 2 2 1 RWP-RK domain HTH_8 PF02954.19 EKX36821.1 - 0.15 11.8 0.1 1.1 9.1 0.1 2.1 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family RWP-RK PF02042.15 EKX36823.1 - 3.4e-14 52.5 0.1 1.5e-13 50.4 0.1 2.0 2 0 0 2 2 2 1 RWP-RK domain HTH_8 PF02954.19 EKX36823.1 - 0.15 11.8 0.1 1.1 9.1 0.1 2.1 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family WD40 PF00400.32 EKX36824.1 - 0.0012 19.6 2.6 1.8 9.5 0.0 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat PPP4R2 PF09184.11 EKX36824.1 - 0.64 9.6 10.2 1.3 8.6 10.2 1.4 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 EKX36824.1 - 5.8 6.1 36.7 10 5.3 0.5 2.3 2 0 0 2 2 2 0 NOA36 protein TRAP_alpha PF03896.16 EKX36824.1 - 6 6.0 6.3 11 5.2 6.3 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Bin3 PF06859.12 EKX36825.1 - 0.002 18.7 0.2 0.0035 18.0 0.2 1.5 1 1 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_23 PF13489.6 EKX36825.1 - 0.018 14.9 0.1 0.026 14.3 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase domain c-SKI_SMAD_bind PF08782.10 EKX36825.1 - 0.19 12.0 0.1 0.35 11.1 0.1 1.4 1 0 0 1 1 1 0 c-SKI Smad4 binding domain MAP17 PF15807.5 EKX36826.1 - 8e-05 22.9 3.7 8e-05 22.9 3.7 3.7 3 1 0 3 3 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 OATP PF03137.20 EKX36826.1 - 0.00042 18.8 3.2 0.00042 18.8 3.2 3.1 2 1 0 2 2 1 1 Organic Anion Transporter Polypeptide (OATP) family RskA PF10099.9 EKX36826.1 - 0.00081 19.7 0.9 0.0013 19.0 0.9 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA TMEM51 PF15345.6 EKX36826.1 - 0.00092 19.1 8.6 0.0037 17.1 8.6 2.1 1 0 0 1 1 1 1 Transmembrane protein 51 FAM176 PF14851.6 EKX36826.1 - 0.001 18.7 5.9 0.001 18.7 5.9 2.4 1 1 2 3 3 1 1 FAM176 family Spt20 PF12090.8 EKX36826.1 - 0.0012 18.5 29.9 0.0016 18.1 29.9 1.2 1 0 0 1 1 1 1 Spt20 family SpoIIIAH PF12685.7 EKX36826.1 - 0.0032 17.3 5.1 0.0032 17.3 5.1 3.6 2 1 0 2 2 1 1 SpoIIIAH-like protein Tmemb_9 PF05434.11 EKX36826.1 - 0.0049 16.8 18.2 0.0049 16.8 18.2 6.7 1 1 1 2 2 1 1 TMEM9 DDHD PF02862.17 EKX36826.1 - 0.0063 16.7 3.4 0.0076 16.4 3.4 1.1 1 0 0 1 1 1 1 DDHD domain G0-G1_switch_2 PF15103.6 EKX36826.1 - 0.0071 16.8 4.2 0.012 16.0 4.2 1.3 1 0 0 1 1 1 1 G0/G1 switch protein 2 Eapp_C PF10238.9 EKX36826.1 - 0.0085 16.2 10.1 0.012 15.8 10.1 1.1 1 0 0 1 1 1 1 E2F-associated phosphoprotein Connexin PF00029.19 EKX36826.1 - 0.011 15.5 13.3 0.011 15.5 13.3 3.9 1 1 1 2 2 1 0 Connexin AIF_C PF14721.6 EKX36826.1 - 0.011 16.0 2.1 0.02 15.2 2.1 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF913 PF06025.12 EKX36826.1 - 0.013 14.5 6.0 0.018 14.0 6.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) LRR19-TM PF15176.6 EKX36826.1 - 0.014 15.4 2.0 0.014 15.4 2.0 7.4 2 1 1 3 3 1 0 Leucine-rich repeat family 19 TM domain DUF3402 PF11882.8 EKX36826.1 - 0.016 14.4 9.8 0.024 13.8 9.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) TRAP_alpha PF03896.16 EKX36826.1 - 0.016 14.4 1.8 0.016 14.4 1.8 2.2 2 1 0 2 2 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2852 PF11014.8 EKX36826.1 - 0.023 14.8 2.6 0.023 14.8 2.6 3.2 1 1 1 2 2 1 0 Protein of unknown function (DUF2852) CPSF100_C PF13299.6 EKX36826.1 - 0.027 14.7 5.4 0.036 14.3 5.4 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SpoIIP PF07454.11 EKX36826.1 - 0.028 13.9 8.5 0.035 13.6 8.5 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) UPF0239 PF06783.11 EKX36826.1 - 0.031 14.4 6.2 0.29 11.3 6.2 2.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) DUF2722 PF10846.8 EKX36826.1 - 0.037 13.0 28.4 0.045 12.7 28.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Miga PF10265.9 EKX36826.1 - 0.059 12.3 8.1 0.078 11.9 8.1 1.1 1 0 0 1 1 1 0 Mitoguardin TFIIA PF03153.13 EKX36826.1 - 0.06 13.3 27.2 0.073 13.1 27.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HemX PF04375.14 EKX36826.1 - 0.078 12.3 20.2 0.15 11.4 20.2 1.4 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DNApol_Exo PF18136.1 EKX36826.1 - 0.079 12.1 6.6 0.1 11.7 6.6 1.1 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain EPL1 PF10513.9 EKX36826.1 - 0.13 12.6 11.2 0.18 12.2 11.2 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF3371 PF11851.8 EKX36826.1 - 0.16 13.1 13.8 0.21 12.7 13.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) DUF4638 PF15472.6 EKX36826.1 - 0.17 11.6 11.3 0.2 11.4 11.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) TFB6 PF17110.5 EKX36826.1 - 0.19 11.5 6.0 0.27 11.0 6.0 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Gastrin PF00918.17 EKX36826.1 - 0.23 12.4 9.4 0.58 11.1 9.4 1.7 1 0 0 1 1 1 0 Gastrin/cholecystokinin family R_equi_Vir PF05526.11 EKX36826.1 - 0.27 11.1 3.2 0.49 10.2 3.2 1.4 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein CRF1 PF10380.9 EKX36826.1 - 0.29 11.5 6.3 0.43 10.9 6.3 1.2 1 0 0 1 1 1 0 Transcription factor CRF1 TERB2 PF15101.6 EKX36826.1 - 0.3 11.1 15.8 0.4 10.7 15.8 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Med15 PF09606.10 EKX36826.1 - 0.37 9.4 26.1 0.45 9.1 26.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Rxt3 PF08642.10 EKX36826.1 - 0.55 11.0 5.0 0.84 10.4 5.0 1.2 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 DUF702 PF05142.12 EKX36826.1 - 0.61 10.6 11.2 0.81 10.2 11.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) eIF-3_zeta PF05091.12 EKX36826.1 - 0.62 9.0 14.7 0.79 8.6 14.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Gti1_Pac2 PF09729.9 EKX36826.1 - 0.84 9.7 9.2 1.1 9.3 9.2 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Band_3_cyto PF07565.13 EKX36826.1 - 1 9.1 10.0 1.4 8.7 10.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain RED_N PF07808.13 EKX36826.1 - 1.1 8.7 13.7 1.5 8.4 13.7 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region Pex14_N PF04695.13 EKX36826.1 - 1.2 9.8 18.5 1.9 9.1 18.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3365 PF11845.8 EKX36826.1 - 1.2 9.5 7.3 6 7.2 7.3 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) MMU163 PF17119.5 EKX36826.1 - 1.3 8.1 6.5 1.9 7.6 6.5 1.1 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Stig1 PF04885.13 EKX36826.1 - 1.5 9.3 9.1 2.7 8.5 9.1 1.4 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 MMR1 PF08505.10 EKX36826.1 - 1.7 8.9 15.4 2.2 8.5 15.4 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Suf PF05843.14 EKX36826.1 - 1.8 8.5 16.2 2.4 8.1 16.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4770 PF15994.5 EKX36826.1 - 2.3 8.4 12.6 3 8.0 12.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) FAM150 PF15129.6 EKX36826.1 - 3.6 7.8 11.5 5.2 7.2 11.5 1.2 1 0 0 1 1 1 0 FAM150 family RR_TM4-6 PF06459.12 EKX36826.1 - 6.9 6.4 14.0 15 5.3 14.0 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Roughex PF06020.11 EKX36826.1 - 8 5.4 14.7 11 4.9 14.7 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Rav1p_C PF12234.8 EKX36827.1 - 1.9e-19 69.5 3.6 1.9e-19 69.5 3.6 2.0 1 1 1 2 2 2 1 RAVE protein 1 C terminal WD40 PF00400.32 EKX36827.1 - 0.0011 19.8 8.7 7.3 7.6 0.0 6.3 6 0 0 6 6 6 1 WD domain, G-beta repeat MMS1_N PF10433.9 EKX36827.1 - 0.021 13.4 0.0 0.056 12.1 0.0 1.5 1 1 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term VID27_N PF17748.1 EKX36827.1 - 0.24 11.2 8.5 0.27 11.1 4.8 2.4 2 1 0 2 2 2 0 VID27 N-terminal region MAP17 PF15807.5 EKX36827.1 - 0.25 11.6 4.6 0.58 10.4 4.6 1.6 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Peptidase_S49_N PF08496.10 EKX36827.1 - 0.39 10.8 4.0 0.94 9.5 4.0 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Cytomega_UL84 PF06284.11 EKX36827.1 - 0.45 8.9 4.9 0.74 8.2 4.9 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein FAM176 PF14851.6 EKX36827.1 - 0.49 10.0 6.2 1.1 8.9 6.2 1.6 1 0 0 1 1 1 0 FAM176 family CPSF100_C PF13299.6 EKX36827.1 - 0.54 10.4 4.7 1.3 9.2 4.7 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Phage_Gp23 PF10669.9 EKX36827.1 - 2.4 8.5 8.2 6 7.2 8.2 1.7 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Casc1_N PF15927.5 EKX36827.1 - 3.7 7.2 17.3 8.9 5.9 17.3 1.6 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Chorion_2 PF03964.15 EKX36827.1 - 6.4 7.7 11.2 24 5.9 0.8 2.7 2 0 0 2 2 2 0 Chorion family 2 TrfA PF07042.11 EKX36828.1 - 0.12 11.4 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 TrfA protein Glutaredoxin PF00462.24 EKX36829.1 - 2e-19 69.6 0.0 2.7e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 EKX36829.1 - 5.8e-05 23.4 0.0 7.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) DUF5633 PF18656.1 EKX36829.1 - 0.00053 19.8 0.3 0.082 12.8 0.0 2.4 2 0 0 2 2 2 2 Family of unknown function (DUF5633) DSBA PF01323.20 EKX36829.1 - 0.0014 18.5 0.2 0.01 15.6 0.0 2.0 2 0 0 2 2 2 1 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 EKX36829.1 - 0.01 16.3 0.0 0.013 16.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EKX36829.1 - 0.064 13.0 0.0 0.084 12.6 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin TraF PF13728.6 EKX36829.1 - 0.13 12.0 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Glutaredoxin PF00462.24 EKX36830.1 - 3.8e-20 71.9 0.0 6.8e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 EKX36830.1 - 4.3e-05 23.8 0.0 4.7e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 EKX36830.1 - 0.00039 20.9 0.0 0.00039 20.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain DSBA PF01323.20 EKX36830.1 - 0.00041 20.2 1.2 0.0019 18.0 0.1 2.0 1 1 0 2 2 2 1 DSBA-like thioredoxin domain TraF PF13728.6 EKX36830.1 - 0.00094 19.1 0.0 0.001 18.9 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 EKX36830.1 - 0.0067 16.4 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain GST_N_3 PF13417.6 EKX36830.1 - 0.019 15.4 0.0 0.023 15.1 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_9 PF14595.6 EKX36830.1 - 0.023 14.5 0.0 0.025 14.3 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_4 PF13462.6 EKX36830.1 - 0.056 13.6 0.3 0.37 10.9 0.3 1.9 1 1 1 2 2 2 0 Thioredoxin Kinesin PF00225.23 EKX36831.1 - 6.9e-102 340.8 0.4 8.4e-102 340.5 0.4 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX36831.1 - 1e-49 168.3 0.0 2.8e-49 166.9 0.0 1.7 2 0 0 2 2 2 1 Microtubule binding ERM PF00769.19 EKX36831.1 - 0.63 9.8 11.8 1.5 8.6 5.0 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF1664 PF07889.12 EKX36831.1 - 1.1 9.3 3.6 1.9 8.6 1.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 EKX36831.1 - 1.3 8.2 8.6 2 7.6 5.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) ResIII PF04851.15 EKX36831.1 - 1.5 8.8 5.3 2.4 8.1 0.5 3.0 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit ATG16 PF08614.11 EKX36831.1 - 1.5 9.0 16.0 0.041 14.1 6.0 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) AAA_22 PF13401.6 EKX36831.1 - 1.7 8.9 5.3 0.65 10.3 0.5 2.7 2 1 0 2 2 2 0 AAA domain DUF4515 PF14988.6 EKX36831.1 - 2.3 8.0 15.0 0.23 11.3 7.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) Beta_helix PF13229.6 EKX36832.1 - 8.3e-39 133.0 23.4 1e-20 74.2 10.2 2.0 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 EKX36832.1 - 5.8e-19 68.3 5.8 3.1e-11 43.0 0.8 2.2 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.7 EKX36832.1 - 0.00051 20.0 4.9 0.0057 16.5 0.6 2.3 1 1 2 3 3 3 3 Pectate lyase superfamily protein HK PF02110.15 EKX36832.1 - 0.13 11.6 0.1 0.26 10.6 0.1 1.5 2 0 0 2 2 2 0 Hydroxyethylthiazole kinase family Peptidase_S8 PF00082.22 EKX36833.1 - 1.2e-38 133.1 3.7 2.3e-20 73.0 0.2 2.6 2 0 0 2 2 2 2 Subtilase family DUF4215 PF13948.6 EKX36833.1 - 8.6e-11 42.1 55.7 4.9e-05 23.7 13.1 5.3 5 0 0 5 5 5 3 Domain of unknown function (DUF4215) EGF_Tenascin PF18720.1 EKX36833.1 - 0.00056 19.9 10.0 0.0051 16.8 10.0 2.9 1 0 0 1 1 1 1 Tenascin EGF domain PA PF02225.22 EKX36833.1 - 0.00096 19.1 0.0 0.0042 17.1 0.0 2.1 2 0 0 2 2 2 1 PA domain Ank_2 PF12796.7 EKX36834.1 - 1e-10 42.0 0.0 2.2e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX36834.1 - 1.5e-08 34.2 0.1 3.6e-05 23.8 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EKX36834.1 - 6.8e-08 32.9 0.4 5.4e-05 23.7 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX36834.1 - 0.001 19.3 0.1 0.0055 17.0 0.1 2.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX36834.1 - 0.0038 17.6 0.2 0.1 13.1 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat MORN PF02493.20 EKX36836.1 - 8.9e-24 81.9 15.7 2.1e-08 33.6 2.9 4.1 4 0 0 4 4 4 4 MORN repeat P5CR_dimer PF14748.6 EKX36840.1 - 1.1e-33 115.5 0.0 2.5e-33 114.4 0.0 1.6 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EKX36840.1 - 1.6e-14 54.3 0.1 2.5e-14 53.6 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EKX36840.1 - 1e-07 32.2 0.3 2.2e-07 31.2 0.3 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EKX36840.1 - 0.00055 20.0 0.0 0.00095 19.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 EKX36840.1 - 0.016 16.0 0.0 0.029 15.2 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_Gly3P_dh_N PF01210.23 EKX36840.1 - 0.033 14.2 1.2 0.55 10.2 1.2 2.1 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 EKX36840.1 - 0.089 12.1 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PB1 PF00564.24 EKX36841.1 - 6.9e-07 29.1 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 PB1 domain MarR_2 PF12802.7 EKX36841.1 - 0.00011 22.0 0.3 0.0002 21.2 0.3 1.4 1 0 0 1 1 1 1 MarR family Sigma70_r4 PF04545.16 EKX36841.1 - 0.00091 18.7 0.3 0.0014 18.1 0.3 1.3 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 EKX36841.1 - 0.0011 18.7 0.3 0.0036 17.0 0.3 1.8 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 EKX36841.1 - 0.0023 17.6 0.1 0.0081 15.9 0.2 1.8 2 0 0 2 2 2 1 Homeodomain-like domain HTH_3 PF01381.22 EKX36841.1 - 0.0028 17.7 0.0 0.0058 16.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_Crp_2 PF13545.6 EKX36841.1 - 0.0029 17.5 0.1 0.0053 16.7 0.1 1.4 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain HTH_28 PF13518.6 EKX36841.1 - 0.012 15.8 0.1 0.025 14.7 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_31 PF13560.6 EKX36841.1 - 0.018 15.4 0.1 0.034 14.5 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_37 PF13744.6 EKX36841.1 - 0.071 13.1 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_19 PF12844.7 EKX36841.1 - 0.078 13.0 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_IclR PF09339.10 EKX36841.1 - 0.12 12.2 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain MarR PF01047.22 EKX36841.1 - 0.12 12.3 0.1 0.59 10.1 0.0 2.0 2 0 0 2 2 2 0 MarR family Cro PF09048.10 EKX36841.1 - 0.13 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Cro HTH_24 PF13412.6 EKX36841.1 - 0.17 11.5 0.1 0.29 10.7 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Phage_int_SAM_4 PF13495.6 EKX36842.1 - 0.00057 20.3 0.2 0.18 12.3 0.0 2.8 3 0 0 3 3 3 2 Phage integrase, N-terminal SAM-like domain PipA PF07108.11 EKX36843.1 - 0.00044 19.8 0.2 0.00081 19.0 0.1 1.5 2 0 0 2 2 2 1 PipA protein DDE_Tnp_1_2 PF13586.6 EKX36843.1 - 0.062 13.7 0.6 0.11 12.9 0.6 1.4 1 0 0 1 1 1 0 Transposase DDE domain Arm PF00514.23 EKX36844.1 - 6.9 6.9 24.0 13 6.0 0.2 7.4 2 1 6 9 9 9 0 Armadillo/beta-catenin-like repeat DSPn PF14671.6 EKX36845.1 - 2.9e-26 92.6 0.3 1.7e-25 90.1 0.0 2.2 2 1 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EKX36845.1 - 3.3e-13 49.6 0.0 5.3e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX36845.1 - 2e-06 27.5 0.0 7.2e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EKX36845.1 - 0.0014 18.7 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EKX36845.1 - 0.0032 17.6 0.0 0.0051 16.9 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Auto_anti-p27 PF06677.12 EKX36846.1 - 4.6e-11 42.7 0.1 8.3e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) MgtE PF01769.16 EKX36847.1 - 0.024 15.0 3.6 0.024 15.0 3.6 2.5 3 1 0 3 3 3 0 Divalent cation transporter DUF4079 PF13301.6 EKX36847.1 - 0.024 14.8 0.0 0.28 11.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) Lustrin_cystein PF14625.6 EKX36848.1 - 0.0048 17.2 120.6 3.4 8.1 0.8 15.4 1 1 12 13 13 13 9 Lustrin, cysteine-rich repeated domain AChE_tetra PF08674.10 EKX36848.1 - 0.45 10.2 2.6 25 4.7 0.2 2.8 2 0 0 2 2 2 0 Acetylcholinesterase tetramerisation domain Acetate_kinase PF00871.17 EKX36850.1 - 0.071 11.8 2.0 0.096 11.4 2.0 1.1 1 0 0 1 1 1 0 Acetokinase family DUF86 PF01934.17 EKX36850.1 - 0.12 12.3 0.7 0.19 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF86 Hydin_ADK PF17213.3 EKX36850.1 - 0.21 11.8 5.7 0.35 11.1 5.7 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Colicin PF01024.19 EKX36851.1 - 0.0085 16.0 0.1 0.014 15.3 0.1 1.2 1 0 0 1 1 1 1 Colicin pore forming domain RdRP PF05183.12 EKX36852.1 - 0.012 14.3 0.8 0.014 14.0 0.8 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase Ephrin_rec_like PF07699.13 EKX36853.1 - 9.7e-08 31.7 50.8 2.8e-05 23.8 6.1 13.6 9 3 5 14 14 14 7 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX36853.1 - 2.1e-07 31.2 45.7 0.00043 20.6 4.4 15.7 7 4 8 16 16 16 8 TNFR/NGFR cysteine-rich region Kelch_1 PF01344.25 EKX36855.1 - 1.5e-31 107.7 8.5 9.1e-13 47.6 0.2 5.8 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 EKX36855.1 - 8.3e-23 79.9 2.8 3.8e-09 36.5 0.0 5.2 3 2 3 6 6 6 4 Kelch motif Kelch_2 PF07646.15 EKX36855.1 - 1.5e-13 50.1 1.7 2.2e-06 27.4 0.0 5.2 5 1 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 EKX36855.1 - 4.6e-13 49.1 0.3 0.055 13.8 0.0 5.4 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_4 PF13418.6 EKX36855.1 - 1.4e-09 37.8 1.8 0.00013 21.9 0.0 4.9 4 2 2 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 EKX36855.1 - 8e-07 28.9 0.2 0.014 15.3 0.0 2.8 2 0 0 2 2 2 2 Kelch motif Vault PF01505.18 EKX36855.1 - 0.15 12.3 0.4 0.33 11.1 0.0 1.8 2 0 0 2 2 2 0 Major Vault Protein repeat domain PQQ_3 PF13570.6 EKX36855.1 - 0.23 12.0 1.4 3.4 8.3 0.0 2.8 3 0 0 3 3 3 0 PQQ-like domain PP2C PF00481.21 EKX36856.1 - 1.2e-05 25.1 0.2 1.4e-05 24.9 0.2 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PRKCSH-like PF12999.7 EKX36856.1 - 0.0084 15.9 0.1 0.009 15.8 0.1 1.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like eIF-5_eIF-2B PF01873.17 EKX36858.1 - 8.5e-30 103.0 1.7 1.5e-29 102.3 1.7 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 DUF1682 PF07946.14 EKX36858.1 - 0.0021 17.3 14.2 0.0034 16.6 14.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) PPP4R2 PF09184.11 EKX36858.1 - 0.0027 17.3 15.4 0.0032 17.1 15.4 1.2 1 0 0 1 1 1 1 PPP4R2 CDC45 PF02724.14 EKX36858.1 - 0.0093 14.3 15.2 0.012 13.9 15.2 1.3 1 0 0 1 1 1 1 CDC45-like protein SAPS PF04499.15 EKX36858.1 - 0.071 11.9 8.0 0.073 11.9 8.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 EKX36858.1 - 0.089 10.9 4.9 0.11 10.6 4.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDHD PF02862.17 EKX36858.1 - 0.3 11.2 4.0 0.37 10.9 4.0 1.4 1 0 0 1 1 1 0 DDHD domain U79_P34 PF03064.16 EKX36858.1 - 0.46 9.8 17.3 0.62 9.4 17.3 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 ALMT PF11744.8 EKX36858.1 - 0.47 9.2 6.1 0.57 8.9 6.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter FAM60A PF15396.6 EKX36858.1 - 0.5 10.3 13.3 0.85 9.6 13.3 1.3 1 0 0 1 1 1 0 Protein Family FAM60A RNA_pol_Rpc4 PF05132.14 EKX36858.1 - 0.54 10.7 15.9 1 9.7 15.9 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 RPOL_N PF14700.6 EKX36858.1 - 0.66 9.3 14.7 0.95 8.8 14.7 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal Nop14 PF04147.12 EKX36858.1 - 0.78 7.9 25.6 1 7.5 25.6 1.1 1 0 0 1 1 1 0 Nop14-like family Astro_capsid_p PF12226.8 EKX36858.1 - 1 8.4 12.8 1.6 7.8 12.8 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Serinc PF03348.15 EKX36858.1 - 1.1 8.1 3.3 1.3 7.9 3.3 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) RR_TM4-6 PF06459.12 EKX36858.1 - 1.1 9.0 18.9 1.6 8.5 18.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2722 PF10846.8 EKX36858.1 - 1.4 7.8 17.9 1.7 7.5 17.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Coilin_N PF15862.5 EKX36858.1 - 1.8 8.4 25.2 4.3 7.1 25.2 1.7 1 0 0 1 1 1 0 Coilin N-terminus Neur_chan_memb PF02932.16 EKX36858.1 - 1.9 8.5 3.9 2.4 8.2 3.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Dsh_C PF12316.8 EKX36858.1 - 2.3 8.6 4.8 3.7 7.9 4.8 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal SET PF00856.28 EKX36858.1 - 4.5 7.6 9.2 9.1 6.6 9.2 1.5 1 1 0 1 1 1 0 SET domain DUF913 PF06025.12 EKX36858.1 - 5.1 6.0 11.5 7.3 5.5 11.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SLC12 PF03522.15 EKX36858.1 - 5.3 6.0 12.5 7 5.6 12.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CDC27 PF09507.10 EKX36858.1 - 9.8 5.4 32.6 14 5.0 32.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Anticodon_1 PF08264.13 EKX36859.1 - 1.6e-27 96.3 0.4 2.8e-27 95.5 0.4 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1 PF00133.22 EKX36859.1 - 1.2e-16 60.1 0.0 2.4e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Motile_Sperm PF00635.26 EKX36859.1 - 0.027 14.3 0.1 0.048 13.5 0.1 1.4 1 0 0 1 1 1 0 MSP (Major sperm protein) domain ISPD_C PF18706.1 EKX36859.1 - 0.097 12.3 0.4 2 8.0 0.1 2.3 2 0 0 2 2 2 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain NAD_binding_10 PF13460.6 EKX36860.1 - 2.7e-20 73.0 0.0 4.4e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EKX36860.1 - 1.8e-11 44.0 0.0 3e-11 43.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EKX36860.1 - 2.1e-11 43.9 0.0 2.8e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 EKX36860.1 - 1.4e-06 28.0 0.0 2.3e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EKX36860.1 - 6.4e-05 22.1 0.1 9.8e-05 21.5 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EKX36860.1 - 0.0017 17.5 0.0 0.0047 16.1 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 EKX36860.1 - 0.0021 18.0 0.1 0.018 14.9 0.0 2.0 1 1 1 2 2 2 1 KR domain adh_short PF00106.25 EKX36860.1 - 0.0031 17.0 0.0 0.005 16.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EKX36860.1 - 0.032 13.4 0.0 0.049 12.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Glyco_trans_4_2 PF13477.6 EKX36860.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like ELFV_dehydrog PF00208.21 EKX36860.1 - 0.14 11.8 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DapB_N PF01113.20 EKX36860.1 - 0.15 12.2 0.2 0.28 11.3 0.2 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 EKX36860.1 - 0.2 10.8 0.0 0.38 9.9 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein PP2C PF00481.21 EKX36862.1 - 1.7e-19 70.5 0.1 1.3e-17 64.3 0.1 2.9 1 1 0 1 1 1 1 Protein phosphatase 2C Thioredoxin PF00085.20 EKX36863.1 - 1.4e-15 57.2 0.0 2.6e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin TolA_bind_tri PF16331.5 EKX36863.1 - 0.03 14.4 0.5 0.03 14.4 0.5 3.3 1 1 2 3 3 3 0 TolA binding protein trimerisation HAP1_N PF04849.13 EKX36863.1 - 0.045 12.9 6.9 0.075 12.2 6.9 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Thioredoxin_2 PF13098.6 EKX36863.1 - 0.064 13.7 0.1 0.43 11.0 0.1 2.3 1 1 0 1 1 1 0 Thioredoxin-like domain AhpC-TSA PF00578.21 EKX36863.1 - 0.077 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family TPR_MLP1_2 PF07926.12 EKX36863.1 - 0.12 12.5 9.8 1.1 9.4 1.4 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein BST2 PF16716.5 EKX36863.1 - 0.12 13.0 6.0 0.65 10.6 0.8 3.1 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 Glutaredoxin PF00462.24 EKX36863.1 - 0.13 12.5 0.1 0.41 10.9 0.0 1.9 1 1 0 1 1 1 0 Glutaredoxin Phage_GP20 PF06810.11 EKX36863.1 - 0.14 12.0 2.8 6.1 6.6 0.2 2.4 1 1 0 2 2 2 0 Phage minor structural protein GP20 TMF_DNA_bd PF12329.8 EKX36863.1 - 0.27 11.3 2.8 12 5.9 0.3 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Hamartin PF04388.12 EKX36863.1 - 1.2 7.7 29.1 1.5 7.4 29.1 1.1 1 0 0 1 1 1 0 Hamartin protein HIP1_clath_bdg PF16515.5 EKX36863.1 - 1.3 9.6 12.4 1.6 9.4 0.8 3.5 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.11 EKX36863.1 - 1.6 7.6 8.8 4.6 6.0 8.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Peptidase_S64 PF08192.11 EKX36863.1 - 8.5 4.7 19.2 11 4.4 19.2 1.3 1 0 0 1 1 1 0 Peptidase family S64 CHDCT2 PF08074.11 EKX36864.1 - 0.013 15.6 3.6 0.013 15.6 3.6 2.7 2 1 1 3 3 3 0 CHDCT2 (NUC038) domain DUF4250 PF14056.6 EKX36864.1 - 0.062 13.3 0.3 2.5 8.1 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) Ycf1 PF05758.12 EKX36864.1 - 0.32 8.8 7.5 0.44 8.3 7.5 1.1 1 0 0 1 1 1 0 Ycf1 KOG2701 PF09762.9 EKX36865.1 - 1.6e-55 188.1 0.0 1.6e-55 188.1 0.0 3.8 3 1 0 3 3 3 1 Coiled-coil domain-containing protein (DUF2037) DUF1593 PF07632.11 EKX36865.1 - 0.092 12.2 4.1 0.079 12.4 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1593) Oxidored_q6 PF01058.22 EKX36865.1 - 0.22 11.3 0.4 0.72 9.7 0.4 1.8 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase, 20 Kd subunit MCD_N PF17408.2 EKX36865.1 - 2.2 8.4 6.0 13 6.0 0.1 4.4 3 2 1 4 4 4 0 Malonyl-CoA decarboxylase N-terminal domain Baculo_PEP_C PF04513.12 EKX36865.1 - 2.5 8.1 10.9 0.41 10.7 0.8 3.3 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 EKX36865.1 - 8.7 6.4 20.1 4.5 7.3 4.8 4.0 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Ank_2 PF12796.7 EKX36867.1 - 2e-27 95.6 5.8 3.7e-11 43.4 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX36867.1 - 4.3e-24 84.6 10.9 1.5e-07 31.8 0.3 5.3 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX36867.1 - 3.2e-19 68.7 8.4 7.2e-08 32.5 0.4 5.3 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX36867.1 - 2.9e-18 64.1 8.2 0.011 16.1 0.0 6.5 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 EKX36867.1 - 2e-17 62.8 13.8 0.00025 21.4 0.1 6.2 6 0 0 6 6 6 5 Ankyrin repeat CENP-B_dimeris PF09026.10 EKX36869.1 - 0.00081 19.7 14.6 0.0011 19.3 14.6 1.2 1 0 0 1 1 1 1 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 EKX36869.1 - 0.0077 14.4 12.3 0.0087 14.2 12.3 1.1 1 0 0 1 1 1 1 DNA polymerase phi DUF4637 PF15470.6 EKX36869.1 - 0.011 15.4 1.4 0.013 15.2 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) BUD22 PF09073.10 EKX36869.1 - 0.018 14.4 2.1 0.016 14.6 2.1 1.1 1 0 0 1 1 1 0 BUD22 FAM176 PF14851.6 EKX36869.1 - 0.025 14.3 3.8 0.037 13.7 3.8 1.3 1 0 0 1 1 1 0 FAM176 family SDA1 PF05285.12 EKX36869.1 - 0.039 13.4 6.4 0.043 13.2 6.4 1.1 1 0 0 1 1 1 0 SDA1 Pkinase PF00069.25 EKX36869.1 - 0.044 13.1 0.0 0.044 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain GCIP PF13324.6 EKX36869.1 - 0.056 13.0 2.3 0.062 12.9 2.3 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Nop14 PF04147.12 EKX36869.1 - 0.12 10.6 8.8 0.14 10.4 8.8 1.0 1 0 0 1 1 1 0 Nop14-like family eIF-3c_N PF05470.12 EKX36869.1 - 0.15 10.3 0.4 0.13 10.6 0.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PI3K_1B_p101 PF10486.9 EKX36869.1 - 0.25 9.1 0.5 0.24 9.1 0.5 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Radial_spoke PF04712.12 EKX36869.1 - 0.44 9.4 4.5 0.47 9.3 4.5 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Pes-10 PF07149.11 EKX36869.1 - 0.61 9.1 13.5 0.75 8.8 13.5 1.1 1 0 0 1 1 1 0 Pes-10 Trypan_PARP PF05887.11 EKX36869.1 - 1.1 9.3 6.4 1.5 8.8 6.4 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF688 PF05097.12 EKX36869.1 - 1.2 8.2 3.8 1.8 7.6 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF688) SGT1 PF07093.11 EKX36869.1 - 1.3 7.4 4.4 1.4 7.2 4.4 1.1 1 0 0 1 1 1 0 SGT1 protein Rhabdo_ncap PF00945.18 EKX36869.1 - 1.5 7.6 4.4 1.9 7.3 4.4 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Cwf_Cwc_15 PF04889.12 EKX36869.1 - 2.5 7.7 13.3 3.3 7.4 13.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 EKX36869.1 - 2.7 8.0 8.5 4 7.5 8.5 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal CobT PF06213.12 EKX36869.1 - 4.5 6.6 11.5 6.5 6.1 11.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop53 PF07767.11 EKX36869.1 - 6 6.2 8.4 7.8 5.8 8.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RRN3 PF05327.11 EKX36869.1 - 9 4.7 8.9 5.2 5.5 7.5 1.3 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2634 PF10934.8 EKX36870.1 - 0.14 12.3 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2634) Ion_trans PF00520.31 EKX36873.1 - 2.4e-36 125.2 20.7 3.6e-36 124.6 20.7 1.3 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EKX36873.1 - 1.1e-06 27.6 16.3 3.8e-06 25.8 16.3 1.8 1 1 0 1 1 1 1 Polycystin cation channel PH PF00169.29 EKX36873.1 - 6.8e-05 23.3 0.0 0.00024 21.6 0.0 2.0 1 1 0 1 1 1 1 PH domain Myelin_PLP PF01275.19 EKX36873.1 - 0.095 12.5 1.4 0.2 11.5 1.4 1.5 1 0 0 1 1 1 0 Myelin proteolipid protein (PLP or lipophilin) Noc2 PF03715.13 EKX36874.1 - 1.8e-85 286.8 0.4 2.4e-85 286.4 0.4 1.1 1 0 0 1 1 1 1 Noc2p family RIX1 PF08167.12 EKX36874.1 - 0.015 15.1 0.2 0.035 13.9 0.0 1.7 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis PDZ_6 PF17820.1 EKX36875.1 - 3.8e-05 23.4 0.0 0.00037 20.3 0.0 2.6 3 0 0 3 3 3 1 PDZ domain WD40 PF00400.32 EKX36876.1 - 6.8e-39 131.2 24.8 6.2e-05 23.7 0.1 9.4 9 0 0 9 9 9 8 WD domain, G-beta repeat PQQ_3 PF13570.6 EKX36876.1 - 5.8e-09 36.2 3.8 1.1 9.8 0.3 7.3 6 3 2 8 8 8 3 PQQ-like domain Nup160 PF11715.8 EKX36876.1 - 5.7e-08 31.9 10.4 0.031 12.9 0.1 5.3 1 1 5 6 6 6 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EKX36876.1 - 6.5e-05 23.2 1.9 0.84 10.0 0.1 4.7 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EKX36876.1 - 0.035 13.7 8.7 0.92 9.0 2.3 3.8 2 1 1 3 3 3 0 PQQ-like domain Sas10 PF09368.10 EKX36877.1 - 1.5e-19 70.2 9.2 1.5e-19 70.2 9.2 5.1 5 1 1 6 6 6 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 EKX36877.1 - 1.4e-11 44.8 0.1 1.4e-11 44.8 0.1 3.6 3 1 0 3 3 3 1 Sas10/Utp3/C1D family Apolipoprotein PF01442.18 EKX36878.1 - 0.00033 20.6 26.6 0.00033 20.6 26.6 12.1 1 1 8 10 10 10 3 Apolipoprotein A1/A4/E domain ORF6C PF10552.9 EKX36878.1 - 0.0048 17.0 1.0 0.11 12.6 0.1 4.0 2 0 0 2 2 2 1 ORF6C domain PDZ_2 PF13180.6 EKX36879.1 - 1.9e-17 63.3 0.9 5.7e-08 33.0 0.1 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EKX36879.1 - 1.1e-15 57.2 0.5 1.1e-07 31.5 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 EKX36879.1 - 2.1e-14 53.6 0.7 1.3e-06 28.6 0.1 2.6 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 EKX36879.1 - 1.1e-05 25.3 0.6 0.044 13.8 0.1 2.6 2 0 0 2 2 2 2 Tricorn protease PDZ domain GAS PF13851.6 EKX36879.1 - 0.0019 17.6 12.9 0.0019 17.6 12.9 2.1 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding DUF641 PF04859.12 EKX36879.1 - 0.006 16.9 5.3 0.006 16.9 5.3 2.1 1 1 1 2 2 2 1 Plant protein of unknown function (DUF641) Spc7 PF08317.11 EKX36879.1 - 0.019 13.9 11.8 0.044 12.7 11.8 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Macoilin PF09726.9 EKX36879.1 - 0.038 12.6 5.9 0.039 12.5 5.9 1.2 1 0 0 1 1 1 0 Macoilin family DivIC PF04977.15 EKX36879.1 - 0.041 13.6 13.8 0.36 10.6 6.2 2.7 1 1 1 2 2 2 0 Septum formation initiator V_ATPase_I PF01496.19 EKX36879.1 - 0.092 10.7 1.5 0.14 10.1 1.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_13 PF13166.6 EKX36879.1 - 0.11 11.1 5.1 0.19 10.4 5.1 1.3 1 0 0 1 1 1 0 AAA domain TerB_N PF13208.6 EKX36879.1 - 0.13 11.9 0.3 0.43 10.2 0.2 2.0 2 0 0 2 2 2 0 TerB N-terminal domain DUF4407 PF14362.6 EKX36879.1 - 0.2 11.0 4.7 0.23 10.8 3.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Sec8_exocyst PF04048.14 EKX36879.1 - 0.37 10.7 6.4 0.1 12.5 2.1 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain PKcGMP_CC PF16808.5 EKX36879.1 - 1.1 9.2 12.4 1.1 9.1 4.8 2.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CC2-LZ PF16516.5 EKX36879.1 - 1.1 9.7 16.2 0.27 11.6 3.3 3.3 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Atg14 PF10186.9 EKX36879.1 - 1.3 8.0 5.7 2.6 7.1 5.7 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_DNA_bd PF12329.8 EKX36879.1 - 7.3 6.7 23.9 2.6 8.1 10.5 3.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DNA_primase_S PF01896.19 EKX36880.1 - 2.7e-47 161.1 0.3 4.3e-47 160.4 0.3 1.3 1 0 0 1 1 1 1 DNA primase small subunit RNase_PH PF01138.21 EKX36881.1 - 2.4e-31 109.0 0.0 2.1e-17 63.8 0.0 2.9 3 0 0 3 3 3 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EKX36881.1 - 3.8e-13 49.3 3.4 5.8e-11 42.3 0.2 3.0 3 0 0 3 3 3 2 3' exoribonuclease family, domain 2 S1 PF00575.23 EKX36881.1 - 5.9e-13 49.0 0.7 1.4e-12 47.8 0.2 2.0 2 0 0 2 2 2 1 S1 RNA binding domain KH_1 PF00013.29 EKX36881.1 - 1.1e-10 41.2 0.3 2.5e-10 40.0 0.3 1.6 1 0 0 1 1 1 1 KH domain KH_5 PF13184.6 EKX36881.1 - 7.3e-05 22.8 1.1 0.00019 21.5 0.1 2.1 2 0 0 2 2 2 1 NusA-like KH domain Glyco_transf_18 PF15024.6 EKX36882.1 - 6.5e-08 31.6 9.5 1.5e-07 30.4 2.7 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 18 Uso1_p115_C PF04871.13 EKX36883.1 - 1.7e-05 25.2 24.3 0.068 13.5 0.0 4.4 2 1 2 4 4 4 3 Uso1 / p115 like vesicle tethering protein, C terminal region PDZ_6 PF17820.1 EKX36883.1 - 0.0011 18.7 0.1 0.0026 17.6 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX36883.1 - 0.0018 18.6 0.3 0.0047 17.2 0.0 1.8 2 0 0 2 2 1 1 PDZ domain KASH_CCD PF14662.6 EKX36883.1 - 0.0022 17.9 14.1 0.0022 17.9 14.1 3.9 3 1 1 4 4 4 1 Coiled-coil region of CCDC155 or KASH PDZ_2 PF13180.6 EKX36883.1 - 0.0034 17.7 0.1 0.0082 16.4 0.1 1.6 1 0 0 1 1 1 1 PDZ domain LptF_LptG PF03739.14 EKX36883.1 - 0.048 12.5 0.1 0.11 11.4 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG TMCO5 PF14992.6 EKX36883.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.8 3 1 0 3 3 2 0 TMCO5 family APG6_N PF17675.1 EKX36883.1 - 0.2 12.2 38.2 0.091 13.3 9.0 3.6 2 1 1 3 3 3 0 Apg6 coiled-coil region DivIC PF04977.15 EKX36883.1 - 0.43 10.4 25.7 0.33 10.7 1.2 4.5 2 1 2 4 4 4 0 Septum formation initiator DUF3450 PF11932.8 EKX36883.1 - 0.95 8.7 26.6 0.04 13.2 1.5 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF3450) MPM1 PF17234.2 EKX36883.1 - 1.6 8.9 7.4 4.7 7.5 7.4 1.8 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Lebercilin PF15619.6 EKX36883.1 - 2 8.1 39.2 0.32 10.6 1.8 4.6 2 1 2 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease PIN_3 PF13470.6 EKX36883.1 - 2.4 9.0 5.6 11 6.8 5.2 2.3 1 1 0 1 1 1 0 PIN domain Cnn_1N PF07989.11 EKX36883.1 - 3.1 8.0 30.7 1.4 9.2 0.4 5.1 4 1 2 6 6 6 0 Centrosomin N-terminal motif 1 bZIP_1 PF00170.21 EKX36883.1 - 6.3 7.0 38.4 0.2 11.8 2.6 5.1 2 1 2 4 4 4 0 bZIP transcription factor TSC22 PF01166.18 EKX36883.1 - 6.4 7.2 19.7 8.5 6.8 2.4 5.0 4 1 0 4 4 4 0 TSC-22/dip/bun family GIT_CC PF16559.5 EKX36883.1 - 8.7 6.3 18.7 3.2 7.7 0.3 5.3 3 1 2 6 6 6 0 GIT coiled-coil Rho guanine nucleotide exchange factor Ax_dynein_light PF10211.9 EKX36883.1 - 8.7 6.2 34.8 1.1 9.2 0.8 4.4 3 1 1 4 4 4 0 Axonemal dynein light chain ApoO PF09769.9 EKX36883.1 - 8.9 6.3 5.6 29 4.6 1.0 3.1 3 1 1 4 4 3 0 Apolipoprotein O WD40 PF00400.32 EKX36884.1 - 2.8e-09 37.4 0.7 0.032 15.1 0.1 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.8 EKX36884.1 - 1.9e-05 23.6 0.0 2.7e-05 23.0 0.0 1.3 1 1 0 1 1 1 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EKX36884.1 - 0.00058 20.1 0.1 0.98 9.8 0.0 2.4 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ion_trans_2 PF07885.16 EKX36885.1 - 6.3e-12 45.3 1.3 6.3e-12 45.3 1.3 1.9 2 0 0 2 2 2 1 Ion channel SK_channel PF03530.14 EKX36885.1 - 2.6e-06 27.4 0.0 8.1e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 Calcium-activated SK potassium channel Ion_trans PF00520.31 EKX36885.1 - 3.3e-05 23.3 9.0 0.00013 21.3 9.0 2.1 1 1 0 1 1 1 1 Ion transport protein Ribosomal_L4 PF00573.22 EKX36886.1 - 6.1e-39 133.7 0.1 6.1e-39 133.7 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 EKX36886.1 - 2.1e-25 88.5 1.7 2.1e-25 88.5 1.7 2.9 2 2 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain FtsJ PF01728.19 EKX36887.1 - 6.7e-58 195.7 0.1 9.3e-58 195.2 0.1 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 EKX36887.1 - 3e-32 111.7 2.1 5.6e-32 110.8 2.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 EKX36887.1 - 0.0072 16.2 0.0 0.021 14.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain DUF5610 PF18433.1 EKX36888.1 - 0.12 12.9 0.1 0.38 11.3 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5610) Ribosomal_L27A PF00828.19 EKX36890.1 - 1.6e-21 77.3 0.1 2.5e-21 76.7 0.0 1.3 1 1 1 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ephrin_rec_like PF07699.13 EKX36891.1 - 0.00079 19.1 65.0 0.0025 17.5 1.5 8.0 5 3 3 8 8 8 6 Putative ephrin-receptor like LRR19-TM PF15176.6 EKX36891.1 - 0.038 14.0 0.4 0.074 13.0 0.4 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF3094 PF11293.8 EKX36891.1 - 0.19 11.5 0.7 0.42 10.4 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) SP_C-Propep PF08999.10 EKX36891.1 - 0.63 9.9 1.9 0.83 9.5 0.3 2.0 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide Acetyltransf_1 PF00583.25 EKX36892.1 - 1e-14 54.7 0.0 1.4e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EKX36892.1 - 6.2e-11 42.3 0.0 8.6e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EKX36892.1 - 6.1e-09 36.2 0.0 8.5e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EKX36892.1 - 0.00014 22.0 0.1 0.00021 21.5 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EKX36892.1 - 0.0003 20.7 0.0 0.0005 20.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EKX36892.1 - 0.015 15.9 0.0 0.018 15.7 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PRELI PF04707.14 EKX36894.1 - 3.6e-21 75.6 0.4 9.8e-19 67.7 0.2 2.1 2 0 0 2 2 2 2 PRELI-like family Gly_rich PF12810.7 EKX36894.1 - 0.039 13.9 0.3 0.053 13.4 0.3 1.1 1 0 0 1 1 1 0 Glycine rich protein SPX PF03105.19 EKX36895.1 - 0.0015 18.5 8.4 0.011 15.6 0.1 3.6 2 1 2 4 4 4 2 SPX domain DUF5352 PF17303.2 EKX36895.1 - 0.13 12.1 1.2 3.7 7.4 0.1 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5352) Zn_clus PF00172.18 EKX36896.1 - 5.8e-05 23.1 9.2 9.8e-05 22.4 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5021 PF16424.5 EKX36897.1 - 0.032 14.1 0.1 0.041 13.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5021) CUE PF02845.16 EKX36898.1 - 0.079 12.7 0.0 0.16 11.7 0.0 1.5 2 0 0 2 2 2 0 CUE domain CUE PF02845.16 EKX36899.1 - 0.1 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 CUE domain FeoB_Cyto PF17910.1 EKX36900.1 - 0.0083 16.7 1.9 0.0083 16.7 1.9 1.9 2 0 0 2 2 2 1 FeoB cytosolic helical domain APG17 PF04108.12 EKX36900.1 - 0.0091 15.2 6.8 0.042 13.0 1.1 2.2 2 0 0 2 2 2 2 Autophagy protein Apg17 V-SNARE_C PF12352.8 EKX36900.1 - 0.02 15.2 4.0 0.4 11.0 0.7 2.7 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus APG6_N PF17675.1 EKX36900.1 - 0.027 15.0 10.6 0.1 13.1 4.9 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region HK97-gp10_like PF04883.12 EKX36900.1 - 0.19 12.7 4.8 0.16 13.0 1.3 2.2 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component BRE1 PF08647.11 EKX36900.1 - 0.2 11.7 11.2 1.7 8.7 1.3 3.2 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase T3SSipB PF16535.5 EKX36900.1 - 0.21 12.0 17.3 0.22 12.0 0.5 2.4 1 1 1 2 2 2 0 Type III cell invasion protein SipB UPF0004 PF00919.20 EKX36900.1 - 0.22 11.6 2.7 0.22 11.6 0.9 1.9 1 1 1 2 2 2 0 Uncharacterized protein family UPF0004 BAG PF02179.16 EKX36900.1 - 0.63 10.5 5.4 4.1 7.9 0.4 3.2 2 2 1 3 3 3 0 BAG domain Spc7 PF08317.11 EKX36900.1 - 0.66 8.8 12.1 3.7 6.3 0.0 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF2408 PF10303.9 EKX36900.1 - 5.8 7.5 10.0 20 5.8 10.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) OmpH PF03938.14 EKX36900.1 - 8.7 6.7 14.3 28 5.1 9.8 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) EH_Signature PF15611.6 EKX36901.1 - 0.23 10.8 0.0 0.23 10.8 0.0 2.0 2 1 0 2 2 2 0 EH_Signature domain Synaptobrevin PF00957.21 EKX36902.1 - 2.3e-29 101.0 1.8 4.5e-29 100.1 1.8 1.5 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EKX36902.1 - 5.9e-21 74.3 0.8 9.2e-21 73.7 0.8 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Polyketide_cyc PF03364.20 EKX36904.1 - 0.19 12.0 0.0 0.26 11.5 0.0 1.2 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport LNS2 PF08235.13 EKX36905.1 - 5.6e-47 160.1 0.0 7.2e-36 123.8 0.0 2.1 2 0 0 2 2 2 2 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EKX36905.1 - 1.2e-07 31.6 0.0 2.2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 lipin, N-terminal conserved region PDZ PF00595.24 EKX36906.1 - 1e-06 29.0 0.0 2.1e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX36906.1 - 1.7e-05 24.6 0.0 3.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX36906.1 - 3.9e-05 23.9 0.0 8.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain zf-C2H2_2 PF12756.7 EKX36906.1 - 0.0032 17.8 1.1 0.0074 16.6 1.1 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EKX36906.1 - 0.065 14.1 4.7 0.18 12.7 4.7 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 EKX36906.1 - 0.12 12.2 1.1 0.26 11.2 1.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) SET PF00856.28 EKX36908.1 - 3.7e-10 40.4 1.1 2.1e-06 28.3 0.3 2.3 1 1 1 2 2 2 2 SET domain WD40 PF00400.32 EKX36909.1 - 6.1e-18 64.9 0.1 1.7e-06 28.6 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX36909.1 - 2.4e-11 43.8 0.0 0.23 11.8 0.0 4.9 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EKX36909.1 - 0.019 13.7 0.0 0.031 12.9 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF5046 PF16465.5 EKX36909.1 - 0.026 14.0 0.0 0.054 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5046) Ras PF00071.22 EKX36911.1 - 2e-59 199.8 0.9 3.1e-59 199.2 0.9 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EKX36911.1 - 6.2e-36 123.2 1.1 1.8e-35 121.8 1.1 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Motile_Sperm PF00635.26 EKX36911.1 - 1.1e-32 112.2 0.0 1.7e-15 56.8 0.0 2.5 2 0 0 2 2 2 2 MSP (Major sperm protein) domain Arf PF00025.21 EKX36911.1 - 8.2e-21 74.2 0.3 1.6e-20 73.3 0.3 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EKX36911.1 - 5.2e-08 32.7 1.6 2.5e-06 27.2 1.6 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EKX36911.1 - 2.8e-07 30.6 0.1 9.8e-07 28.9 0.1 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EKX36911.1 - 5.7e-07 29.1 0.1 1.2e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EKX36911.1 - 4.1e-06 26.3 0.3 6.4e-06 25.7 0.3 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EKX36911.1 - 0.002 18.0 0.1 2.2 8.1 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EKX36911.1 - 0.0079 15.7 0.1 0.056 13.0 0.1 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B IL17R_fnIII_D1 PF16556.5 EKX36911.1 - 0.008 15.8 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 1 Interleukin-17 receptor, fibronectin-III-like domain 1 CPT PF07931.12 EKX36911.1 - 0.0099 15.7 0.1 0.021 14.7 0.1 1.5 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_24 PF13479.6 EKX36911.1 - 0.027 14.2 0.2 0.46 10.2 0.1 2.7 2 1 0 2 2 2 0 AAA domain SNF2_N PF00176.23 EKX36911.1 - 0.094 11.4 0.7 0.15 10.7 0.1 1.6 2 0 0 2 2 2 0 SNF2 family N-terminal domain Glyco_hydro_30C PF17189.4 EKX36911.1 - 0.095 12.9 0.2 9.6 6.5 0.0 3.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 30 beta sandwich domain TniB PF05621.11 EKX36911.1 - 0.11 11.9 0.0 0.27 10.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial TniB protein JUPITER PF17054.5 EKX36912.1 - 0.23 10.9 3.0 0.33 10.4 3.0 1.1 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter SR-25 PF10500.9 EKX36912.1 - 0.26 10.8 19.5 0.43 10.1 19.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CCDC24 PF15669.5 EKX36912.1 - 0.62 9.9 4.1 6.4 6.6 4.4 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family IQCJ-SCHIP1 PF15157.6 EKX36912.1 - 1.9 8.3 7.4 3.6 7.4 7.4 1.4 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif WW PF00397.26 EKX36913.1 - 1.6e-05 24.8 0.2 3.8e-05 23.7 0.2 1.7 1 0 0 1 1 1 1 WW domain RPN2_C PF18004.1 EKX36913.1 - 0.44 10.4 6.5 0.6 10.0 6.5 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PUF PF00806.19 EKX36915.1 - 3.4e-18 64.2 0.1 0.0073 16.0 0.0 8.6 9 0 0 9 9 9 4 Pumilio-family RNA binding repeat Mem_trans PF03547.18 EKX36915.1 - 0.21 9.9 0.9 0.32 9.4 0.9 1.5 1 0 0 1 1 1 0 Membrane transport protein OST3_OST6 PF04756.13 EKX36917.1 - 3.7e-08 33.1 0.2 4.5e-08 32.8 0.2 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family FHA PF00498.26 EKX36918.1 - 1.8e-13 50.6 1.0 5.8e-13 49.0 0.6 2.0 1 1 1 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EKX36918.1 - 7.9e-07 29.3 0.0 1.7e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Bunya_RdRp PF04196.12 EKX36918.1 - 0.044 12.1 0.3 0.063 11.6 0.3 1.1 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase Ras PF00071.22 EKX36919.1 - 6.3e-48 162.4 0.2 7.4e-48 162.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EKX36919.1 - 2.3e-26 92.3 0.1 3.2e-26 91.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EKX36919.1 - 3.9e-09 36.2 0.0 4.8e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EKX36919.1 - 1.2e-05 24.8 0.0 1.3e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EKX36919.1 - 0.00057 19.9 0.0 0.00074 19.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EKX36919.1 - 0.00068 19.6 0.0 0.7 9.8 0.0 2.5 1 1 1 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 EKX36919.1 - 0.013 15.0 0.0 0.051 13.1 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 EKX36919.1 - 0.015 15.5 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 EKX36919.1 - 0.017 14.2 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_7 PF12775.7 EKX36919.1 - 0.18 11.3 0.0 0.36 10.3 0.0 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Adap_comp_sub PF00928.21 EKX36920.1 - 8.6e-20 71.2 0.0 1.4e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EKX36920.1 - 0.0012 18.8 0.2 0.0019 18.1 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TLC PF03219.14 EKX36921.1 - 5.6e-150 500.3 22.0 7.1e-150 500.0 22.0 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter Ndc1_Nup PF09531.10 EKX36921.1 - 0.54 8.9 6.3 0.18 10.5 2.5 1.9 2 1 0 2 2 2 0 Nucleoporin protein Ndc1-Nup PDZ_6 PF17820.1 EKX36922.1 - 4.5e-13 48.8 0.2 7.4e-13 48.1 0.2 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX36922.1 - 9.1e-11 42.0 0.5 1.4e-10 41.4 0.5 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX36922.1 - 5.5e-08 33.0 0.1 1e-07 32.1 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX36922.1 - 0.0062 16.5 0.2 0.016 15.1 0.2 1.7 1 1 0 1 1 1 1 Tricorn protease PDZ domain SAM_2 PF07647.17 EKX36923.1 - 2.5e-11 43.5 0.0 1.3e-05 25.2 0.0 2.3 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EKX36923.1 - 4e-06 27.2 0.0 0.0023 18.3 0.0 2.3 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) Pkinase PF00069.25 EKX36924.1 - 4.5e-10 39.3 0.0 6.4e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX36924.1 - 0.032 13.5 0.0 0.041 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 EKX36925.1 - 1.3e-09 37.8 0.0 2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX36925.1 - 0.00016 21.1 0.0 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase LsmAD PF06741.13 EKX36925.1 - 1.2 9.8 0.1 1.2 9.8 0.1 2.4 2 1 0 2 2 2 0 LsmAD domain Vps26 PF03643.15 EKX36926.1 - 1.4e-28 99.7 0.1 1.6e-28 99.5 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 EF-hand_8 PF13833.6 EKX36928.1 - 1.9e-05 24.4 0.9 1.9e-05 24.4 0.9 2.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX36928.1 - 4.9e-05 22.6 5.2 0.00061 19.1 0.5 2.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EKX36928.1 - 0.0019 18.0 3.0 0.9 9.6 0.1 3.0 2 1 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EKX36928.1 - 0.0086 16.5 3.3 0.13 12.8 0.3 2.3 1 1 0 2 2 2 1 EF-hand domain pair AAA_12 PF13087.6 EKX36930.1 - 4.1e-41 140.8 0.1 1.5e-40 138.9 0.0 2.1 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 EKX36930.1 - 2.9e-18 66.6 0.3 4.2e-16 59.5 0.0 3.3 3 1 0 3 3 3 2 AAA domain Ribosomal_L24e PF01246.20 EKX36931.1 - 1.7e-30 105.0 9.0 1.7e-30 105.0 9.0 1.9 2 1 0 2 2 2 1 Ribosomal protein L24e zf-FCS PF06467.14 EKX36931.1 - 0.052 13.5 13.2 0.12 12.4 11.7 2.1 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif MIT PF04212.18 EKX36932.1 - 2.2e-09 37.2 1.5 2.2e-09 37.2 1.5 2.8 3 1 0 3 3 3 1 MIT (microtubule interacting and transport) domain DUF2951 PF11166.8 EKX36932.1 - 0.075 13.3 1.6 0.14 12.4 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) HHH_9 PF17674.1 EKX36932.1 - 3.2 8.7 8.7 10 7.1 0.0 3.7 3 1 1 4 4 4 0 HHH domain Kelch_4 PF13418.6 EKX36933.1 - 4.4e-28 97.0 8.2 1.7e-07 31.1 0.0 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EKX36933.1 - 4.9e-25 87.3 7.5 2.4e-09 37.2 0.0 7.2 8 0 0 8 8 8 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EKX36933.1 - 7.6e-20 70.5 4.2 2.9e-05 24.0 0.0 6.1 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.25 EKX36933.1 - 2.4e-18 65.4 7.6 6.3e-05 22.5 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 EKX36933.1 - 2.8e-16 59.2 5.2 0.0014 18.8 0.0 5.7 4 1 1 5 5 5 4 Kelch motif Fic PF02661.18 EKX36933.1 - 3.7e-14 53.4 0.0 9.8e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 Fic/DOC family Kelch_2 PF07646.15 EKX36933.1 - 1.8e-13 49.9 11.6 0.00084 19.2 0.0 6.6 5 1 0 5 5 5 4 Kelch motif GRP PF07172.11 EKX36934.1 - 0.0035 18.0 8.6 0.0047 17.6 8.6 1.2 1 0 0 1 1 1 1 Glycine rich protein family ARS2 PF04959.13 EKX36934.1 - 1 9.7 6.5 1.3 9.3 6.5 1.2 1 0 0 1 1 1 0 Arsenite-resistance protein 2 GET2 PF08690.10 EKX36934.1 - 8.5 5.9 7.1 9.5 5.8 7.1 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Sporozoite_P67 PF05642.11 EKX36934.1 - 9.4 4.2 8.0 10 4.0 8.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RhoGAP PF00620.27 EKX36935.1 - 3.6e-39 134.0 0.1 1e-38 132.5 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 EKX36935.1 - 6.2e-14 52.3 0.0 1.3e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain PH PF00169.29 EKX36935.1 - 6.7e-14 52.3 0.0 2e-13 50.7 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 EKX36935.1 - 0.001 19.4 0.0 0.0048 17.3 0.0 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain TPR_1 PF00515.28 EKX36935.1 - 0.0012 18.6 0.1 0.0029 17.3 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX36935.1 - 0.0013 18.6 0.1 0.0051 16.8 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX36935.1 - 0.0079 16.2 0.9 0.019 15.1 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat PH_11 PF15413.6 EKX36935.1 - 0.031 14.7 0.0 3.4 8.1 0.0 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain TIC20 PF16166.5 EKX36937.1 - 4.1e-24 85.3 2.1 5.3e-24 85.0 2.1 1.1 1 0 0 1 1 1 1 Chloroplast import apparatus Tic20-like MacB_PCD PF12704.7 EKX36939.1 - 0.16 12.3 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 MacB-like periplasmic core domain Pigment_DH PF06324.11 EKX36939.1 - 0.19 11.9 2.8 11 6.4 0.0 3.6 3 0 0 3 3 3 0 Pigment-dispersing hormone (PDH) DnaJ PF00226.31 EKX36940.1 - 8.2e-20 70.7 1.4 2.3e-19 69.3 1.4 1.8 1 0 0 1 1 1 1 DnaJ domain Tmemb_185A PF10269.9 EKX36940.1 - 3.2e-19 69.6 6.7 5.3e-19 68.9 6.7 1.5 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein DUF1980 PF09323.10 EKX36940.1 - 0.0006 19.8 0.3 0.0037 17.2 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1980) Orf78 PF06024.12 EKX36940.1 - 0.14 12.5 0.1 8.7 6.7 0.0 3.0 3 0 0 3 3 3 0 Orf78 (ac78) His_Phos_1 PF00300.22 EKX36941.1 - 9.3e-32 110.3 0.1 1.2e-31 109.9 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Arf PF00025.21 EKX36942.1 - 3.7e-59 199.1 0.0 4.1e-59 198.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EKX36942.1 - 4.9e-15 55.5 0.0 5.5e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EKX36942.1 - 2.3e-14 53.6 0.0 3.7e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EKX36942.1 - 5e-11 42.4 0.0 6.2e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EKX36942.1 - 9.6e-10 38.1 0.2 2.7e-06 26.8 0.0 2.5 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 EKX36942.1 - 1e-08 35.3 0.0 1.4e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EKX36942.1 - 1e-08 34.8 0.0 1.3e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EKX36942.1 - 0.00097 18.7 0.2 0.035 13.6 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EKX36942.1 - 0.0038 17.2 0.1 0.74 9.7 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase MobB PF03205.14 EKX36942.1 - 0.043 13.7 0.0 0.1 12.5 0.0 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 EKX36942.1 - 0.072 13.6 0.0 0.15 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 EKX36942.1 - 0.075 12.6 0.2 0.33 10.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B cobW PF02492.19 EKX36942.1 - 0.11 12.1 0.7 6.2 6.4 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PatG_C PF18065.1 EKX36945.1 - 0.062 13.3 0.5 0.15 12.1 0.5 1.6 1 0 0 1 1 1 0 PatG C-terminal DUF1307 PF06998.11 EKX36945.1 - 0.24 11.4 2.1 0.45 10.6 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1307) RWP-RK PF02042.15 EKX36946.1 - 2.3e-18 65.9 0.2 4e-18 65.1 0.2 1.4 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX36947.1 - 2.5e-18 65.8 0.2 4e-18 65.1 0.2 1.3 1 0 0 1 1 1 1 RWP-RK domain NUDIX PF00293.28 EKX36948.1 - 2e-14 53.7 0.0 3.2e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DCP2 PF05026.13 EKX36948.1 - 9.5e-11 41.9 0.0 1.7e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Dcp2, box A domain GTP-bdg_M PF16360.5 EKX36950.1 - 3.2 8.4 8.2 3.7 8.2 5.0 2.7 2 1 1 3 3 3 0 GTP-binding GTPase Middle Region PhyH PF05721.13 EKX36951.1 - 9.4e-10 39.1 0.9 5.6e-09 36.6 0.9 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Beta-lactamase2 PF13354.6 EKX36952.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase enzyme family p450 PF00067.22 EKX36953.1 - 1.8e-38 132.5 0.0 2.6e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF1664 PF07889.12 EKX36954.1 - 7 6.7 10.1 1 9.4 3.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Cupin_8 PF13621.6 EKX36955.1 - 5e-18 65.7 0.0 5.9e-11 42.6 0.1 2.6 1 1 1 2 2 2 2 Cupin-like domain JmjC PF02373.22 EKX36955.1 - 2.2e-09 37.7 0.7 8.1e-07 29.5 0.1 2.5 2 1 0 3 3 3 2 JmjC domain, hydroxylase Cupin_4 PF08007.12 EKX36955.1 - 4.6e-07 29.6 0.0 6.9e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 EKX36955.1 - 0.0026 17.4 0.1 0.009 15.7 0.0 1.9 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 EKX36955.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Cupin Trypan_PARP PF05887.11 EKX36957.1 - 0.041 13.8 23.4 0.052 13.5 23.4 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FAM76 PF16046.5 EKX36957.1 - 0.076 12.4 11.2 0.087 12.2 11.2 1.0 1 0 0 1 1 1 0 FAM76 protein NOA36 PF06524.12 EKX36957.1 - 0.31 10.3 20.9 0.42 9.9 20.9 1.3 1 0 0 1 1 1 0 NOA36 protein RNA_pol_Rpc4 PF05132.14 EKX36957.1 - 1.2 9.5 9.4 1.4 9.3 9.4 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 NPR3 PF03666.13 EKX36957.1 - 1.8 7.3 18.1 1.9 7.2 18.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.12 EKX36957.1 - 2.4 7.9 18.5 2.5 7.9 18.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Coilin_N PF15862.5 EKX36957.1 - 2.4 8.0 14.4 3.1 7.6 14.4 1.3 1 0 0 1 1 1 0 Coilin N-terminus AAA_11 PF13086.6 EKX36957.1 - 3.1 7.5 10.8 3.1 7.5 10.8 1.1 1 0 0 1 1 1 0 AAA domain DDHD PF02862.17 EKX36957.1 - 4.9 7.2 9.2 5.3 7.1 9.2 1.1 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 EKX36957.1 - 5.5 5.6 18.2 5.8 5.6 18.2 1.0 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 EKX36957.1 - 5.6 5.9 12.8 5.5 5.9 12.8 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Nop14 PF04147.12 EKX36957.1 - 6.8 4.8 25.1 6.5 4.8 25.1 1.0 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.10 EKX36957.1 - 7.1 6.9 19.2 7.7 6.8 19.2 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CPSF100_C PF13299.6 EKX36957.1 - 8.3 6.6 14.0 9.7 6.3 14.0 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Gti1_Pac2 PF09729.9 EKX36957.1 - 8.3 6.5 15.0 9.6 6.3 15.0 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Connexin PF00029.19 EKX36957.1 - 9.6 5.9 11.8 12 5.5 11.8 1.3 1 0 0 1 1 1 0 Connexin MIT PF04212.18 EKX36958.1 - 0.12 12.5 3.3 0.23 11.6 3.4 1.4 1 1 0 1 1 1 0 MIT (microtubule interacting and transport) domain COG2 PF06148.11 EKX36959.1 - 0.35 11.0 3.5 1 9.5 0.6 2.5 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ABC2_membrane PF01061.24 EKX36963.1 - 2e-32 112.3 29.2 2.8e-32 111.9 29.2 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EKX36963.1 - 2.1e-24 86.6 0.0 3e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EKX36963.1 - 2.6e-07 30.8 0.2 0.0074 16.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EKX36963.1 - 9.7e-05 22.0 0.5 0.00027 20.6 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 EKX36963.1 - 0.0001 21.8 0.0 0.00025 20.6 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EKX36963.1 - 0.0023 18.5 0.1 0.0038 17.8 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EKX36963.1 - 0.0046 17.4 0.0 0.0077 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EKX36963.1 - 0.0081 16.4 0.1 0.029 14.7 0.1 2.1 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 EKX36963.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 EKX36963.1 - 0.021 14.7 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 EKX36963.1 - 0.096 12.4 0.0 0.24 11.1 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.6 EKX36963.1 - 0.11 12.1 0.2 0.27 10.8 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EKX36963.1 - 0.14 12.6 0.0 0.72 10.3 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EKX36963.1 - 0.16 12.5 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Kinocilin PF15033.6 EKX36963.1 - 0.17 11.5 1.2 0.5 10.0 1.2 1.7 1 0 0 1 1 1 0 Kinocilin protein Rad17 PF03215.15 EKX36963.1 - 0.2 11.5 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain DUF677 PF05055.12 EKX36963.1 - 0.21 10.5 0.0 0.36 9.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Iso_dh PF00180.20 EKX36964.1 - 1.4e-23 83.6 0.0 2.3e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase EF-hand_1 PF00036.32 EKX36964.1 - 1.8e-05 24.0 0.1 5.3e-05 22.5 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EKX36964.1 - 0.00013 22.3 0.1 0.00039 20.8 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX36964.1 - 0.00031 20.4 1.1 0.0012 18.7 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 EKX36964.1 - 0.00057 19.3 0.1 0.0015 17.9 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 EKX36964.1 - 0.078 12.8 0.4 0.32 10.9 0.4 2.2 1 1 0 1 1 1 0 EF-hand domain pair DUF5484 PF17583.2 EKX36964.1 - 0.25 11.0 1.4 7.3 6.3 0.0 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5484) DUF1861 PF08950.10 EKX36965.1 - 0.056 12.7 0.0 0.13 11.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1861) CDKN3 PF05706.12 EKX36966.1 - 1.5e-11 44.3 0.1 1.8e-11 44.0 0.1 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) DSPc PF00782.20 EKX36966.1 - 4.5e-08 33.0 0.0 6.7e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX36966.1 - 1.6e-06 27.9 0.0 2.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EKX36966.1 - 0.017 15.1 0.6 0.028 14.4 0.6 1.4 1 1 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EKX36966.1 - 0.019 15.1 0.0 0.047 13.8 0.0 1.6 2 0 0 2 2 2 0 Inositol hexakisphosphate DUF5329 PF17263.2 EKX36966.1 - 0.023 14.9 0.1 0.058 13.6 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5329) DUF442 PF04273.13 EKX36966.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative phosphatase (DUF442) Myosin_head PF00063.21 EKX36969.1 - 1.2e-223 744.1 0.0 1.8e-223 743.6 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 EKX36969.1 - 0.0029 17.9 0.1 0.047 14.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EKX36969.1 - 0.28 11.6 0.0 0.28 11.6 0.0 3.0 4 0 0 4 4 4 0 AAA ATPase domain AAA_18 PF13238.6 EKX36969.1 - 0.33 11.5 0.0 0.33 11.5 0.0 3.2 4 0 0 4 4 4 0 AAA domain PNISR PF15996.5 EKX36969.1 - 0.49 10.6 25.9 1.3 9.3 16.0 2.9 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Integrase_DNA PF02920.15 EKX36969.1 - 2 8.2 8.7 1.2 8.9 0.6 3.3 3 0 0 3 3 3 0 DNA binding domain of tn916 integrase DUF3754 PF12576.8 EKX36970.1 - 6e-10 39.2 0.0 1.2e-09 38.3 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3754) DAP3 PF10236.9 EKX36973.1 - 0.092 11.9 0.0 0.12 11.6 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AsmA PF05170.14 EKX36975.1 - 0.0011 17.8 0.0 0.0023 16.8 0.0 1.4 1 0 0 1 1 1 1 AsmA family DSBA PF01323.20 EKX36976.1 - 0.00037 20.3 0.0 0.0011 18.8 0.0 1.8 1 0 0 1 1 1 1 DSBA-like thioredoxin domain DUF241 PF03087.14 EKX36976.1 - 0.027 14.3 4.9 0.05 13.4 4.9 1.3 1 0 0 1 1 1 0 Arabidopsis protein of unknown function Thioredoxin_4 PF13462.6 EKX36976.1 - 0.045 13.9 0.1 0.53 10.4 0.0 2.4 1 1 1 2 2 2 0 Thioredoxin Oxidored_nitro PF00148.19 EKX36976.1 - 0.11 11.2 0.9 0.21 10.3 0.9 1.5 1 1 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase THOC7 PF05615.13 EKX36976.1 - 1.2 9.4 4.9 0.32 11.3 0.7 2.1 2 1 0 2 2 2 0 Tho complex subunit 7 ASC PF00858.24 EKX36977.1 - 3.4e-26 92.2 17.1 2.2e-24 86.2 17.1 2.8 1 1 0 1 1 1 1 Amiloride-sensitive sodium channel FKBP_N_2 PF18023.1 EKX36977.1 - 0.02 15.0 0.0 0.048 13.8 0.0 1.6 1 0 0 1 1 1 0 BDBT FKBP like N-terminal GRIP PF01465.20 EKX36978.1 - 2.7e-08 33.6 0.1 5.2e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 GRIP domain DUF4972 PF16342.5 EKX36978.1 - 0.071 12.8 0.5 0.12 12.1 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) Fasciclin PF02469.22 EKX36979.1 - 0.0028 17.9 0.0 0.0043 17.3 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain Acyltransferase PF01553.21 EKX36980.1 - 2e-21 76.0 0.0 3e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EKX36980.1 - 3.3e-08 33.5 0.3 9e-08 32.1 0.2 1.7 1 1 1 2 2 2 1 Acyltransferase C-terminus CRISPR_Cse1 PF09481.10 EKX36980.1 - 0.2 10.7 0.1 1.1 8.2 0.0 1.8 2 0 0 2 2 2 0 CRISPR-associated protein Cse1 (CRISPR_cse1) Indigoidine_A PF04227.12 EKX36981.1 - 3.6e-127 423.7 2.3 4.1e-127 423.5 2.3 1.0 1 0 0 1 1 1 1 Indigoidine synthase A like protein Amidohydro_1 PF01979.20 EKX36983.1 - 6.1e-64 216.5 0.8 1e-63 215.8 0.8 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_beta PF00699.20 EKX36983.1 - 1.3e-37 127.7 0.0 3.5e-37 126.4 0.0 1.7 1 0 0 1 1 1 1 Urease beta subunit Urease_alpha PF00449.20 EKX36983.1 - 6e-33 113.7 8.5 2.6e-19 69.7 0.5 3.2 2 1 1 3 3 3 2 Urease alpha-subunit, N-terminal domain Urease_gamma PF00547.18 EKX36983.1 - 3.7e-32 110.6 0.1 8.8e-32 109.4 0.1 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 EKX36983.1 - 4.7e-08 32.9 0.0 8.6e-08 32.1 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Mito_carr PF00153.27 EKX36984.1 - 6.2e-41 138.3 4.3 1.4e-13 50.5 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Pox_VLTF3 PF04947.14 EKX36984.1 - 0.061 13.0 0.1 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 Poxvirus Late Transcription Factor VLTF3 like LRV_FeS PF05484.11 EKX36985.1 - 0.097 12.7 2.9 0.24 11.4 0.6 2.5 2 0 0 2 2 2 0 LRV protein FeS4 cluster Isochorismatase PF00857.20 EKX36986.1 - 2.6e-08 34.3 0.0 4.9e-05 23.6 0.0 2.5 3 0 0 3 3 3 2 Isochorismatase family Big_7 PF17957.1 EKX36986.1 - 0.0011 19.7 0.0 0.0022 18.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial Ig domain Excalibur PF05901.11 EKX36987.1 - 0.045 14.4 0.2 0.049 14.2 0.2 1.4 1 1 0 1 1 1 0 Excalibur calcium-binding domain HEAT PF02985.22 EKX36990.1 - 1.6e-14 52.7 4.4 0.0072 16.5 0.1 7.2 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.6 EKX36990.1 - 6.4e-06 26.5 0.4 1.1 9.7 0.0 5.2 5 1 1 6 6 6 2 HEAT repeats Vac14_Fab1_bd PF12755.7 EKX36990.1 - 0.00077 20.0 0.3 0.21 12.2 0.1 3.2 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EKX36990.1 - 0.0011 19.0 1.9 0.0064 16.5 0.1 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EKX36990.1 - 0.0026 17.4 0.0 2 7.9 0.0 3.3 3 0 0 3 3 3 1 CLASP N terminal HEAT_EZ PF13513.6 EKX36990.1 - 0.034 14.6 3.6 5.1 7.7 0.2 4.3 5 1 0 5 5 5 0 HEAT-like repeat Rop PF01815.16 EKX36990.1 - 0.43 10.5 3.2 0.29 11.0 0.5 2.1 2 0 0 2 2 2 0 Rop protein Pkinase PF00069.25 EKX36991.1 - 2.1e-20 73.2 0.0 2.1e-14 53.5 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EKX36991.1 - 5.2e-06 25.9 0.0 2.2e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase PRY PF13765.6 EKX36991.1 - 0.00018 21.1 0.4 11 5.8 0.0 5.4 2 1 4 6 6 6 1 SPRY-associated domain DUF1521 PF07481.11 EKX36991.1 - 0.065 13.2 7.7 3.1 7.8 1.0 2.7 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1521) Lantibiotic_a PF14867.6 EKX36991.1 - 6.7 6.5 6.8 2.6e+02 1.5 0.0 4.6 5 0 0 5 5 5 0 Lantibiotic alpha FtsK_alpha PF17854.1 EKX36994.1 - 0.095 12.9 2.6 0.38 10.9 0.2 3.0 2 0 0 2 2 2 0 FtsK alpha domain Pribosyltran PF00156.27 EKX36996.1 - 1.4e-09 37.7 0.0 2.7e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 EKX36996.1 - 1.4e-06 28.5 0.1 3e-06 27.4 0.0 1.6 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain UPRTase PF14681.6 EKX36996.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 EKX36996.1 - 0.052 13.1 0.0 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 Phosphoribosyl transferase AMP-binding PF00501.28 EKX36997.1 - 6.1e-72 242.5 0.0 8.7e-72 242.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EKX36997.1 - 7.9e-56 189.1 0.0 4e-55 186.8 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.25 EKX36997.1 - 7.2e-51 172.4 0.3 1.8e-50 171.1 0.3 1.7 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EKX36997.1 - 5e-32 111.3 2.4 6.5e-32 111.0 1.1 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EKX36997.1 - 7e-20 71.5 2.0 1.3e-12 47.7 0.1 3.9 2 2 0 2 2 2 2 NAD dependent epimerase/dehydratase family KR PF08659.10 EKX36997.1 - 3.3e-19 69.5 2.5 3.4e-16 59.7 0.5 2.6 2 0 0 2 2 2 2 KR domain 3Beta_HSD PF01073.19 EKX36997.1 - 5e-16 58.5 0.1 8.7e-12 44.6 0.0 3.0 3 0 0 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EKX36997.1 - 7.2e-09 35.2 0.1 0.0018 17.5 0.0 2.7 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein PP-binding PF00550.25 EKX36997.1 - 1.5e-08 34.8 0.0 3.4e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.17 EKX36997.1 - 2.2e-08 33.5 0.1 3.2e-05 23.2 0.0 2.8 2 1 0 2 2 2 2 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EKX36997.1 - 8.6e-08 31.9 1.0 0.011 15.2 0.0 3.3 3 0 0 3 3 3 3 GDP-mannose 4,6 dehydratase AMP-binding_C PF13193.6 EKX36997.1 - 3.1e-05 24.9 0.0 0.00013 22.9 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.6 EKX36997.1 - 0.00082 19.3 4.8 0.002 18.1 0.4 3.3 4 0 0 4 4 4 1 NAD(P)H-binding DapB_N PF01113.20 EKX36997.1 - 0.13 12.4 0.2 0.47 10.6 0.1 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Phage_Nu1 PF07471.12 EKX36998.1 - 0.053 13.3 0.1 0.79 9.5 0.0 2.3 2 0 0 2 2 2 0 Phage DNA packaging protein Nu1 CysG_dimeriser PF10414.9 EKX36999.1 - 0.0041 16.8 0.6 0.01 15.6 0.6 1.6 1 0 0 1 1 1 1 Sirohaem synthase dimerisation region BTB_2 PF02214.22 EKX37000.1 - 5.5e-12 45.9 0.1 2.1e-08 34.4 0.1 2.5 2 0 0 2 2 2 2 BTB/POZ domain Mito_carr PF00153.27 EKX37001.1 - 3e-40 136.1 1.0 6.8e-20 70.8 0.1 4.4 2 2 2 4 4 4 4 Mitochondrial carrier protein ASH PF15780.5 EKX37002.1 - 1.9e-66 220.4 43.5 0.0018 18.4 0.0 27.7 27 1 1 28 28 28 18 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 EKX37002.1 - 6.5e-35 119.3 4.3 0.00052 19.8 0.0 18.2 19 1 0 19 19 19 6 MSP (Major sperm protein) domain PapD-like PF14874.6 EKX37002.1 - 9.2e-25 86.8 4.7 8.1e-06 25.9 0.0 12.5 14 0 0 14 14 14 4 Flagellar-associated PapD-like DUF1573 PF07610.11 EKX37002.1 - 8.4e-21 73.8 4.5 0.43 10.7 0.0 20.6 25 0 0 25 25 25 1 Protein of unknown function (DUF1573) MYCBPAP PF14646.6 EKX37002.1 - 7.4e-15 54.8 7.0 0.39 9.6 0.0 11.3 12 1 1 13 13 13 5 MYCBP-associated protein family DUF5001 PF16392.5 EKX37002.1 - 4.4e-10 39.3 0.5 4.4 7.3 0.0 11.1 12 1 0 12 12 12 1 Ig-like domain FixG_C PF11614.8 EKX37002.1 - 6.9e-08 32.7 2.9 0.00014 22.1 0.0 6.6 7 0 0 7 7 7 1 IG-like fold at C-terminal of FixG, putative oxidoreductase TMEM131_like PF12371.8 EKX37002.1 - 7.9e-08 32.5 26.8 0.5 10.7 0.0 15.8 21 1 0 21 21 21 2 Transmembrane protein 131-like TFIIF_alpha PF05793.12 EKX37002.1 - 0.77 8.3 8.6 2.2 6.7 8.6 1.7 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF5060 PF16586.5 EKX37002.1 - 1.2 9.6 3.1 48 4.4 0.0 5.1 7 0 0 7 7 7 0 Domain of unknown function (DUF5060) DUF1580 PF07618.11 EKX37004.1 - 0.051 13.2 0.2 7.7 6.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1580) Med2 PF11214.8 EKX37005.1 - 0.021 15.0 0.0 0.025 14.7 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 2 Diphthamide_syn PF01866.17 EKX37006.1 - 2.6e-117 391.6 0.0 3.1e-117 391.3 0.0 1.0 1 0 0 1 1 1 1 Putative diphthamide synthesis protein ATP-synt_C PF00137.21 EKX37007.1 - 6.6e-29 100.0 32.8 4.6e-15 55.7 12.2 2.9 3 0 0 3 3 3 2 ATP synthase subunit C Spore_YhaL PF14147.6 EKX37007.1 - 0.038 13.7 0.8 4 7.2 0.0 2.7 2 0 0 2 2 2 0 Sporulation protein YhaL Oxidored_q2 PF00420.24 EKX37007.1 - 3.1 7.5 9.3 0.63 9.7 0.8 2.6 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Tmemb_cc2 PF10267.9 EKX37008.1 - 0.24 10.5 12.8 0.34 10.0 12.8 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF572 PF04502.13 EKX37008.1 - 1.3 8.6 15.2 2.3 7.8 15.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Branch PF02485.21 EKX37009.1 - 6.5e-25 88.1 0.8 9.3e-25 87.6 0.8 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme RWP-RK PF02042.15 EKX37010.1 - 6.3e-15 54.9 0.0 1.2e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain DUF1838 PF08894.11 EKX37011.1 - 0.073 12.8 0.2 0.1 12.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1838) DNA_pol_B PF00136.21 EKX37013.1 - 1.6e-120 403.0 0.1 2.5e-120 402.3 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EKX37013.1 - 5.7e-43 147.3 0.0 9.7e-43 146.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_2 PF03175.13 EKX37013.1 - 0.00019 20.4 0.1 0.0035 16.3 0.0 2.2 1 1 0 2 2 2 1 DNA polymerase type B, organellar and viral AIRS_C PF02769.22 EKX37014.1 - 6.2e-07 29.7 0.0 3.2e-06 27.3 0.0 2.2 2 1 0 2 2 2 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 EKX37014.1 - 0.01 16.5 0.1 0.022 15.4 0.1 1.5 1 0 0 1 1 1 0 AIR synthase related protein, N-terminal domain PseudoU_synth_2 PF00849.22 EKX37015.1 - 1.5e-14 54.4 0.1 2.4e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 EKX37015.1 - 0.0099 15.6 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 S4 domain Kelch_1 PF01344.25 EKX37015.1 - 0.076 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Kelch motif Filo_glycop PF01611.16 EKX37016.1 - 0.095 11.6 2.2 0.15 10.9 2.2 1.3 1 0 0 1 1 1 0 Filovirus glycoprotein RskA PF10099.9 EKX37017.1 - 0.33 11.2 22.8 1.7 8.9 22.8 2.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA BUD22 PF09073.10 EKX37018.1 - 0.77 9.0 17.0 1.2 8.5 17.0 1.3 1 0 0 1 1 1 0 BUD22 PI3K_1B_p101 PF10486.9 EKX37018.1 - 8.6 4.0 6.2 11 3.7 6.2 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Ribosomal_60s PF00428.19 EKX37019.1 - 3.8e-16 59.4 10.0 1.9e-15 57.2 10.0 1.9 1 1 0 1 1 1 1 60s Acidic ribosomal protein Paralemmin PF03285.15 EKX37019.1 - 0.013 15.1 0.6 0.018 14.6 0.6 1.1 1 0 0 1 1 1 0 Paralemmin Ribosomal_60s PF00428.19 EKX37020.1 - 2.2e-08 34.6 0.1 2.5e-08 34.4 0.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Utp12 PF04003.12 EKX37020.1 - 0.14 12.5 0.0 0.18 12.2 0.0 1.1 1 0 0 1 1 1 0 Dip2/Utp12 Family Ran_BP1 PF00638.18 EKX37021.1 - 1.4e-36 125.4 0.2 3.5e-36 124.1 0.2 1.7 1 0 0 1 1 1 1 RanBP1 domain DUF2052 PF09747.9 EKX37021.1 - 0.09 12.9 15.4 0.029 14.5 2.5 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SDA1 PF05285.12 EKX37021.1 - 2 7.8 17.5 1.8 7.9 3.9 2.1 2 0 0 2 2 2 0 SDA1 BSP_II PF05432.11 EKX37021.1 - 2.2 7.9 18.8 2.4 7.8 5.4 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Myc_N PF01056.18 EKX37021.1 - 2.8 7.7 13.6 0.15 11.9 0.7 2.1 2 0 0 2 2 2 0 Myc amino-terminal region CPSF100_C PF13299.6 EKX37021.1 - 3.5 7.8 7.3 3.4 7.8 0.5 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal MRI PF15325.6 EKX37021.1 - 5.4 8.1 16.8 2 9.6 5.0 2.7 3 0 0 3 3 3 0 Modulator of retrovirus infection RBR PF17208.3 EKX37022.1 - 0.042 14.5 0.5 0.042 14.5 0.5 1.9 2 0 0 2 2 2 0 RNA binding Region YIF1 PF03878.15 EKX37023.1 - 0.013 15.1 1.7 0.02 14.4 1.7 1.3 1 0 0 1 1 1 0 YIF1 YIF1 PF03878.15 EKX37024.1 - 0.019 14.5 1.6 0.031 13.8 1.6 1.3 1 0 0 1 1 1 0 YIF1 PRORP PF16953.5 EKX37025.1 - 7.2e-32 110.8 1.8 6.2e-27 94.7 0.1 3.6 2 2 0 3 3 3 2 Protein-only RNase P PPR_long PF17177.4 EKX37025.1 - 1.4e-21 76.8 0.0 3.3e-21 75.6 0.0 1.5 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EKX37025.1 - 2.1e-07 30.7 7.5 0.46 10.9 0.0 5.0 6 0 0 6 6 6 3 PPR repeat PPR_2 PF13041.6 EKX37025.1 - 2.3e-06 27.7 0.6 0.45 10.7 0.0 4.3 2 1 2 4 4 4 3 PPR repeat family PPR_3 PF13812.6 EKX37025.1 - 1.3e-05 25.1 0.1 0.04 14.0 0.0 3.6 1 1 2 3 3 3 2 Pentatricopeptide repeat domain RNase_Zc3h12a PF11977.8 EKX37025.1 - 5e-05 23.1 0.1 0.00033 20.5 0.1 2.2 1 1 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain TPR_14 PF13428.6 EKX37025.1 - 0.062 14.2 0.0 56 4.9 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_1 PF12854.7 EKX37025.1 - 1.1 9.1 6.8 20 5.0 0.3 3.8 4 0 0 4 4 4 0 PPR repeat Ion_trans PF00520.31 EKX37026.1 - 2.8e-06 26.7 5.9 2.8e-06 26.7 5.9 1.6 2 0 0 2 2 2 1 Ion transport protein Guanylate_cyc PF00211.20 EKX37026.1 - 0.00051 19.7 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Metal_resist PF13801.6 EKX37026.1 - 0.026 14.7 0.1 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 Heavy-metal resistance LRR_8 PF13855.6 EKX37026.1 - 0.072 12.9 2.6 0.29 10.9 2.6 2.1 1 0 0 1 1 1 0 Leucine rich repeat LRR_4 PF12799.7 EKX37026.1 - 0.18 12.3 2.0 0.76 10.3 2.0 2.2 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) DUF5525 PF17663.1 EKX37027.1 - 0.13 10.3 8.3 0.15 10.1 8.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5525) DEC-1_N PF04625.13 EKX37027.1 - 0.19 10.7 8.3 0.2 10.7 8.3 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Rhomboid PF01694.22 EKX37028.1 - 2e-22 79.8 15.5 1.3e-19 70.6 4.9 2.0 1 1 1 2 2 2 2 Rhomboid family Pes-10 PF07149.11 EKX37029.1 - 0.049 12.7 4.4 0.089 11.8 4.4 1.4 1 0 0 1 1 1 0 Pes-10 DUF4746 PF15928.5 EKX37029.1 - 4.2 6.7 12.6 3.7 6.9 11.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4746) DUF2897 PF11446.8 EKX37029.1 - 7.1 6.6 6.4 5.2 7.0 3.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) SH3_2 PF07653.17 EKX37030.1 - 0.0076 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF4797 PF16051.5 EKX37030.1 - 0.39 10.7 1.2 1.5 8.9 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4797) SDA1 PF05285.12 EKX37033.1 - 0.46 9.9 40.1 0.7 9.3 40.1 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EKX37033.1 - 6.7 4.8 44.7 9.1 4.3 44.7 1.2 1 0 0 1 1 1 0 Nop14-like family Bac_rhodopsin PF01036.18 EKX37035.1 - 1e-34 120.1 21.8 1.2e-34 119.8 21.8 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Ion_trans PF00520.31 EKX37036.1 - 3.8e-35 121.3 22.1 5e-35 120.9 22.1 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EKX37036.1 - 8.6e-10 37.9 7.6 8.6e-10 37.9 7.6 2.1 1 1 1 2 2 2 2 Polycystin cation channel EF-hand_1 PF00036.32 EKX37036.1 - 0.00025 20.4 0.1 0.0018 17.7 0.1 2.6 1 1 1 2 2 2 1 EF hand EF-hand_6 PF13405.6 EKX37036.1 - 0.00092 19.0 0.0 0.0069 16.2 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain Ephrin_rec_like PF07699.13 EKX37037.1 - 6.8e-161 522.0 519.1 3.9e-10 39.3 4.0 48.6 38 11 8 47 47 47 41 Putative ephrin-receptor like EGF_CA PF07645.15 EKX37037.1 - 3.4e-06 27.2 11.6 3.4e-06 27.2 11.6 37.8 38 10 5 44 44 44 5 Calcium-binding EGF domain Ephrin_rec_like PF07699.13 EKX37038.1 - 5.9e-35 118.8 85.6 4.4e-08 32.8 5.4 9.8 5 2 4 9 9 9 8 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX37038.1 - 0.00028 21.2 61.7 0.24 11.9 1.2 11.0 5 1 6 12 12 12 10 TNFR/NGFR cysteine-rich region Tudor_3 PF18115.1 EKX37040.1 - 2.4e-05 24.1 0.4 4.9e-05 23.1 0.4 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Laminin_G_3 PF13385.6 EKX37041.1 - 7.9e-11 42.3 3.6 1.5e-10 41.4 3.6 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4215 PF13948.6 EKX37042.1 - 6.8e-06 26.4 5.2 6.8e-06 26.4 5.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4215) ZU5 PF00791.20 EKX37042.1 - 0.00013 22.3 0.0 0.00035 20.9 0.0 1.7 1 0 0 1 1 1 1 ZU5 domain DUF2076 PF09849.9 EKX37042.1 - 0.063 13.3 0.1 0.093 12.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SKG6 PF08693.10 EKX37042.1 - 0.15 11.5 1.8 0.33 10.4 1.8 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain YabA PF06156.13 EKX37043.1 - 0.0056 17.3 3.6 0.008 16.8 3.6 1.4 1 1 0 1 1 1 1 Initiation control protein YabA K-box PF01486.17 EKX37043.1 - 0.3 11.3 5.5 0.43 10.8 1.0 2.0 1 1 1 2 2 2 0 K-box region NYD-SP28_assoc PF14775.6 EKX37043.1 - 4.1 7.6 6.3 21 5.3 1.0 2.7 2 1 1 3 3 3 0 Sperm tail C-terminal domain Glyco_transf_29 PF00777.18 EKX37045.1 - 1.7e-16 60.4 0.0 4e-15 55.9 0.0 2.1 1 1 1 2 2 2 2 Glycosyltransferase family 29 (sialyltransferase) Ank_5 PF13857.6 EKX37048.1 - 6.4e-12 45.5 0.1 7.6e-10 38.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX37048.1 - 7.1e-10 39.2 0.0 1.4e-07 31.9 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX37048.1 - 1.7e-09 37.1 0.0 0.0018 18.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EKX37048.1 - 6.6e-09 36.2 0.0 1.4e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX37048.1 - 2.3e-08 34.1 0.0 0.00022 21.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat K_channel_TID PF07941.11 EKX37048.1 - 0.029 14.8 21.3 0.046 14.2 9.9 2.6 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain PsbQ PF05757.11 EKX37048.1 - 1.6 8.4 5.0 0.96 9.1 0.5 2.1 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) Shadoo PF14999.6 EKX37048.1 - 6.5 6.9 19.7 0.23 11.5 7.4 2.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective PPR_2 PF13041.6 EKX37051.1 - 6.8e-35 119.0 10.4 5.8e-07 29.6 0.0 10.4 9 2 1 10 10 10 8 PPR repeat family PPR_3 PF13812.6 EKX37051.1 - 2.1e-34 117.4 1.3 0.00011 22.2 0.0 9.7 6 3 2 8 8 8 7 Pentatricopeptide repeat domain PPR_long PF17177.4 EKX37051.1 - 1.2e-21 77.0 9.6 5.1e-10 39.1 0.1 5.5 2 1 3 5 5 5 4 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EKX37051.1 - 9.1e-06 25.3 22.1 0.0078 15.9 0.3 9.1 9 1 0 9 9 9 2 PPR repeat ECSIT PF06239.11 EKX37051.1 - 2.2e-05 23.7 0.0 8.8 5.4 0.0 5.7 5 1 1 6 6 6 2 Evolutionarily conserved signalling intermediate in Toll pathway PPR PF01535.20 EKX37051.1 - 0.0031 17.7 32.3 1.5 9.3 0.0 9.8 11 0 0 11 11 11 3 PPR repeat SR-25 PF10500.9 EKX37051.1 - 0.0074 15.9 4.9 0.014 15.0 4.9 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Exog_C PF18026.1 EKX37051.1 - 0.021 14.9 0.1 13 5.9 0.0 4.1 4 0 0 4 4 4 0 Endo/exonuclease (EXOG) C-terminal domain DUF755 PF05501.11 EKX37051.1 - 0.038 14.3 10.1 0.086 13.1 10.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DED PF01335.21 EKX37051.1 - 0.089 13.1 0.1 3.1 8.2 0.1 3.1 3 0 0 3 3 3 0 Death effector domain Ank_2 PF12796.7 EKX37053.1 - 9.7e-07 29.3 0.0 1.3e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX37053.1 - 1.6e-05 25.1 0.0 5e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EKX37053.1 - 3.4e-05 24.0 0.0 6.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX37053.1 - 3.6e-05 23.8 0.0 0.00012 22.2 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EKX37053.1 - 0.013 16.1 0.0 0.028 15.0 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF1828 PF08861.10 EKX37053.1 - 0.1 12.9 0.1 1.5 9.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF1828 DUF3254 PF11630.8 EKX37055.1 - 0.29 11.3 1.6 0.5 10.6 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3254) Spc24 PF08286.11 EKX37055.1 - 0.41 10.9 0.1 0.41 10.9 0.1 6.3 4 2 0 5 5 5 0 Spc24 subunit of Ndc80 ABC1 PF03109.16 EKX37056.1 - 2.1e-22 79.5 0.0 4.8e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 EKX37056.1 - 1.4e-06 27.9 0.0 0.018 14.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 EKX37056.1 - 0.0011 18.9 0.1 0.0053 16.7 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EKX37056.1 - 0.027 14.0 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Arm PF00514.23 EKX37057.1 - 1.2e-19 69.7 0.1 0.0022 18.0 0.0 5.1 5 0 0 5 5 5 5 Armadillo/beta-catenin-like repeat DUF4630 PF15443.6 EKX37057.1 - 2.2e-12 47.5 38.3 0.013 15.7 2.0 5.0 1 1 4 5 5 5 5 Domain of unknown function (DUF4630) HEAT_2 PF13646.6 EKX37057.1 - 5e-08 33.2 9.5 0.048 14.0 0.9 4.6 1 1 4 5 5 5 5 HEAT repeats Atx10homo_assoc PF09759.9 EKX37057.1 - 4.2e-07 29.9 0.0 0.0012 18.8 0.0 3.1 1 1 2 4 4 4 3 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 EKX37057.1 - 0.00032 21.1 12.3 0.3 11.6 0.6 4.8 2 2 2 4 4 4 3 HEAT-like repeat HEAT PF02985.22 EKX37057.1 - 0.014 15.6 11.3 49 4.6 0.1 6.6 5 5 2 7 7 7 0 HEAT repeat SAM_LFY PF01698.16 EKX37057.1 - 0.21 11.6 8.0 89 3.1 0.2 4.9 5 0 0 5 5 5 0 Floricaula / Leafy protein SAM domain PheRS_DBD2 PF18554.1 EKX37057.1 - 2.4 8.2 5.1 1.7e+02 2.3 0.1 4.0 4 0 0 4 4 4 0 PheRS DNA binding domain 2 Pkinase_Tyr PF07714.17 EKX37058.1 - 2.8e-40 138.2 0.0 3.1e-40 138.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX37058.1 - 1.4e-19 70.6 0.0 1.4e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EKX37058.1 - 0.0018 17.1 0.0 0.0047 15.8 0.0 1.7 2 1 0 2 2 2 1 Fungal protein kinase U-box PF04564.15 EKX37059.1 - 2.8e-19 69.0 0.0 3.4e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX37059.1 - 1.1e-06 28.3 0.1 1.5e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EKX37059.1 - 0.00012 22.1 0.1 0.00017 21.6 0.1 1.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-NOSIP PF15906.5 EKX37059.1 - 0.0014 18.7 0.0 0.0018 18.4 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_2 PF13923.6 EKX37059.1 - 0.053 13.4 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CBF PF03914.17 EKX37060.1 - 3.5e-26 92.2 0.1 4.5e-26 91.9 0.1 1.1 1 0 0 1 1 1 1 CBF/Mak21 family STE3 PF02076.15 EKX37061.1 - 0.1 11.8 0.1 0.15 11.2 0.1 1.3 1 0 0 1 1 1 0 Pheromone A receptor Ofd1_CTDD PF10637.9 EKX37062.1 - 3.7e-13 49.4 0.2 2.7e-10 40.0 0.2 3.2 1 1 0 1 1 1 1 Oxoglutarate and iron-dependent oxygenase degradation C-term DUF1912 PF08930.10 EKX37062.1 - 0.066 13.4 0.6 1.1 9.5 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1912) FAM110_C PF14160.6 EKX37063.1 - 1.8e-05 25.8 0.9 2.5e-05 25.3 0.9 1.2 1 0 0 1 1 1 1 Centrosome-associated C terminus DUF2828 PF11443.8 EKX37063.1 - 0.0042 15.2 0.8 0.0048 15.0 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) Presenilin PF01080.17 EKX37063.1 - 0.0086 14.9 1.8 0.0095 14.7 1.8 1.0 1 0 0 1 1 1 1 Presenilin PI3K_1B_p101 PF10486.9 EKX37063.1 - 0.013 13.4 0.3 0.012 13.4 0.3 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Sox_N PF12444.8 EKX37063.1 - 0.013 16.6 0.8 0.021 15.9 0.8 1.4 1 0 0 1 1 1 0 Sox developmental protein N terminal GRP PF07172.11 EKX37063.1 - 0.078 13.7 4.3 0.14 12.9 4.3 1.4 1 0 0 1 1 1 0 Glycine rich protein family YqfQ PF14181.6 EKX37063.1 - 0.12 12.5 5.2 0.15 12.2 5.2 1.2 1 0 0 1 1 1 0 YqfQ-like protein Smg8_Smg9 PF10220.9 EKX37063.1 - 0.17 10.2 2.0 0.2 9.9 2.0 1.0 1 0 0 1 1 1 0 Smg8_Smg9 DUF1980 PF09323.10 EKX37063.1 - 0.26 11.2 3.1 0.39 10.6 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Cytomega_UL84 PF06284.11 EKX37063.1 - 0.28 9.6 1.0 0.31 9.4 1.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF3464 PF11947.8 EKX37063.1 - 0.49 10.1 2.6 0.65 9.7 2.6 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Pkinase PF00069.25 EKX37064.1 - 1.1e-39 136.4 0.0 1.7e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX37064.1 - 2.8e-36 125.1 0.0 1.2e-21 77.2 0.0 2.2 1 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EKX37064.1 - 0.00091 19.2 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX37064.1 - 0.0021 16.9 0.0 0.0034 16.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EKX37065.1 - 4.9e-08 32.7 0.1 5.4e-08 32.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX37065.1 - 1.2e-06 28.0 0.0 1.3e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_3 PF07720.12 EKX37065.1 - 0.052 13.6 0.1 0.69 10.0 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 EKX37066.1 - 3.7e-46 157.6 0.0 5.3e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX37066.1 - 3.9e-44 150.9 0.0 1.3e-29 103.2 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EKX37066.1 - 0.00011 22.2 0.1 0.0052 16.7 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX37066.1 - 0.0018 17.1 0.0 0.0028 16.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EKX37067.1 - 2.9e-46 158.0 0.0 4.8e-46 157.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX37067.1 - 1.9e-44 151.9 0.0 2e-41 142.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX37067.1 - 0.00016 21.7 0.1 0.0051 16.8 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX37067.1 - 0.0005 19.0 0.0 0.0014 17.5 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase CDC45 PF02724.14 EKX37068.1 - 0.15 10.4 19.0 0.25 9.6 19.0 1.3 1 0 0 1 1 1 0 CDC45-like protein PI3K_1B_p101 PF10486.9 EKX37068.1 - 0.87 7.3 10.5 1.3 6.8 10.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit NOA36 PF06524.12 EKX37068.1 - 3 7.1 15.2 7.2 5.8 15.2 1.6 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 EKX37068.1 - 7.6 5.8 31.7 0.13 11.6 23.1 2.1 2 0 0 2 2 2 0 SDA1 RAP PF08373.10 EKX37069.1 - 3.5e-10 39.8 0.0 7e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 RAP domain HTH_11 PF08279.12 EKX37070.1 - 0.029 14.3 0.4 0.56 10.2 0.2 2.2 2 0 0 2 2 2 0 HTH domain MIF PF01187.18 EKX37070.1 - 0.055 13.8 0.1 0.55 10.5 0.0 2.1 1 1 1 2 2 2 0 Macrophage migration inhibitory factor (MIF) Pkinase PF00069.25 EKX37071.1 - 5.3e-47 160.4 0.0 6.3e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX37071.1 - 4.4e-45 154.0 0.0 5.2e-45 153.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX37071.1 - 8.5e-05 22.6 0.0 0.0054 16.7 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX37071.1 - 0.0015 17.4 0.0 0.0023 16.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF4287 PF14117.6 EKX37074.1 - 0.026 14.7 0.0 0.32 11.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4287) Orthopox_B11R PF07033.11 EKX37074.1 - 0.13 12.1 0.0 2.3 8.0 0.0 2.7 3 0 0 3 3 3 0 Orthopoxvirus B11R protein S-antigen PF05756.11 EKX37074.1 - 0.22 11.9 2.9 0.58 10.6 0.3 2.5 2 0 0 2 2 2 0 S-antigen protein Pkinase PF00069.25 EKX37075.1 - 7e-44 150.2 0.0 1.3e-43 149.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX37075.1 - 1.1e-43 149.3 0.0 3.3e-43 147.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX37075.1 - 7.6e-05 22.7 0.1 0.0039 17.1 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX37075.1 - 0.079 11.7 0.0 1 8.1 0.0 2.0 1 1 0 1 1 1 0 Fungal protein kinase SMI1_KNR4 PF09346.10 EKX37076.1 - 7.5e-05 23.1 0.0 0.00015 22.1 0.0 1.5 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Pkinase PF00069.25 EKX37077.1 - 1.7e-42 145.6 0.0 1.9e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX37077.1 - 3.9e-37 128.0 0.0 4.3e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX37077.1 - 6.2e-05 23.0 0.1 0.0035 17.3 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX37077.1 - 6.3e-05 21.9 0.0 0.00018 20.5 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EKX37077.1 - 0.02 14.2 0.0 0.026 13.8 0.0 1.1 1 0 0 1 1 1 0 Kinase-like DUF1517 PF07466.11 EKX37078.1 - 0.0099 16.0 0.0 0.011 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) adh_short PF00106.25 EKX37079.1 - 7.2e-29 100.6 0.1 1.1e-18 67.4 0.0 2.5 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EKX37079.1 - 7.2e-17 61.7 0.1 3.6e-13 49.6 0.0 2.5 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX37079.1 - 0.00017 21.5 0.2 0.36 10.7 0.0 2.1 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 EKX37079.1 - 0.0084 15.4 0.2 0.028 13.8 0.1 1.9 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ADH_zinc_N PF00107.26 EKX37079.1 - 0.038 14.0 0.4 0.12 12.3 0.3 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.8 EKX37079.1 - 0.13 12.0 0.4 0.58 10.0 0.1 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RAM PF15320.6 EKX37079.1 - 1.7 9.3 4.2 1.6 9.3 1.3 2.3 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein CTP_transf_1 PF01148.20 EKX37080.1 - 1.1e-53 182.7 15.0 1.4e-53 182.3 15.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Hid1 PF12722.7 EKX37082.1 - 0.051 11.7 1.1 0.066 11.3 1.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1993 PF09351.10 EKX37082.1 - 0.069 13.3 0.2 0.13 12.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) DUF2201_N PF13203.6 EKX37082.1 - 0.15 11.6 2.8 0.24 11.0 2.8 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain DARPP-32 PF05395.12 EKX37082.1 - 1.8 8.7 13.5 30 4.8 10.6 2.2 2 0 0 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 DUF4589 PF15252.6 EKX37082.1 - 2.5 8.0 5.1 1.5 8.8 2.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4589) RPN2_C PF18004.1 EKX37082.1 - 3 7.8 12.5 0.66 9.9 9.2 1.6 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain tRNA_bind PF01588.20 EKX37083.1 - 5.5e-15 55.2 0.8 8e-15 54.7 0.8 1.3 1 0 0 1 1 1 1 Putative tRNA binding domain WW PF00397.26 EKX37084.1 - 6e-05 23.0 0.3 0.00014 21.9 0.3 1.6 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.9 EKX37084.1 - 0.011 15.8 2.6 0.025 14.6 2.6 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Mating_C PF12737.7 EKX37086.1 - 0.025 13.8 0.6 0.025 13.8 0.6 1.1 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 AMP-binding PF00501.28 EKX37087.1 - 2.2e-44 151.7 0.0 1.1e-24 86.8 0.0 2.5 1 1 1 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 EKX37087.1 - 8.9e-12 45.2 0.1 1.9e-11 44.1 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EKX37087.1 - 2.6e-08 34.7 1.0 6.3e-05 23.9 0.5 2.9 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Hexapep PF00132.24 EKX37087.1 - 1.5e-06 27.7 12.2 9.6e-05 22.0 1.3 5.0 5 0 0 5 5 5 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EKX37087.1 - 0.53 10.1 16.5 0.13 12.0 3.9 4.8 5 0 0 5 5 5 0 Hexapeptide repeat of succinyl-transferase HATPase_c PF02518.26 EKX37089.1 - 2.4e-31 108.5 0.1 4.9e-31 107.5 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EKX37089.1 - 3.7e-16 58.9 0.7 9.1e-16 57.7 0.7 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 EKX37089.1 - 5.6e-14 52.3 0.7 4.1e-13 49.5 0.3 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c_3 PF13589.6 EKX37089.1 - 0.00028 20.7 0.0 0.00048 20.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EKX37089.1 - 0.00073 19.5 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.6 EKX37089.1 - 0.0013 18.6 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 GHKL domain Pkinase PF00069.25 EKX37090.1 - 2e-11 43.7 0.0 8.3e-08 31.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EKX37090.1 - 5.2e-05 22.6 0.0 0.00027 20.3 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX37090.1 - 0.02 13.7 0.2 0.02 13.7 0.2 1.8 2 1 0 2 2 2 0 Fungal protein kinase RIO1 PF01163.22 EKX37090.1 - 0.039 13.5 0.0 0.1 12.2 0.0 1.7 1 1 0 1 1 1 0 RIO1 family APH PF01636.23 EKX37090.1 - 0.047 13.6 0.5 0.093 12.6 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EKX37090.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NiFe-hyd_HybE PF11939.8 EKX37090.1 - 0.2 11.6 0.1 0.2 11.6 0.1 1.8 2 0 0 2 2 2 0 [NiFe]-hydrogenase assembly, chaperone, HybE Peptidase_M41 PF01434.18 EKX37093.1 - 1.6e-66 223.8 1.0 3.2e-66 222.8 1.0 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EKX37093.1 - 1e-43 149.0 0.0 2.3e-43 147.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EKX37093.1 - 9.3e-10 38.2 0.0 2.7e-09 36.7 0.0 1.8 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 EKX37093.1 - 3.7e-06 27.0 0.0 1.7e-05 24.8 0.0 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EKX37093.1 - 6.3e-06 26.0 0.0 2.9e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EKX37093.1 - 7.7e-06 25.3 0.1 1.6e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 EKX37093.1 - 6e-05 23.5 0.4 0.011 16.1 0.2 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EKX37093.1 - 0.00018 21.8 0.5 0.11 12.8 0.1 3.4 1 1 2 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EKX37093.1 - 0.0019 18.0 0.0 0.0041 16.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 EKX37093.1 - 0.008 16.3 0.0 0.033 14.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EKX37093.1 - 0.0088 15.5 0.9 0.024 14.0 0.9 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 EKX37093.1 - 0.013 15.9 0.1 0.1 13.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EKX37093.1 - 0.018 15.2 0.0 0.043 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EKX37093.1 - 0.019 15.5 0.1 0.053 14.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 EKX37093.1 - 0.021 14.3 0.5 0.17 11.4 0.5 2.3 1 1 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 EKX37093.1 - 0.025 13.9 0.2 0.45 9.8 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.6 EKX37093.1 - 0.033 14.4 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EKX37093.1 - 0.045 13.8 0.1 0.094 12.7 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 EKX37093.1 - 0.052 12.7 0.0 0.12 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 EKX37093.1 - 0.06 13.3 0.3 0.92 9.4 0.2 2.2 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 EKX37093.1 - 0.062 13.0 0.2 0.2 11.3 0.1 1.8 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.6 EKX37093.1 - 0.071 13.2 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EKX37093.1 - 0.12 12.1 0.0 0.4 10.4 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 EKX37093.1 - 0.13 11.4 0.1 0.26 10.3 0.0 1.5 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 ERO1 PF04137.15 EKX37093.1 - 0.23 10.6 0.0 0.53 9.4 0.0 1.5 1 0 0 1 1 1 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) ABC_tran PF00005.27 EKX37093.1 - 0.24 11.9 2.1 0.34 11.4 0.8 1.8 2 0 0 2 2 2 0 ABC transporter BolA PF01722.18 EKX37094.1 - 8.1e-26 90.1 0.1 9.7e-26 89.9 0.1 1.1 1 0 0 1 1 1 1 BolA-like protein Glyco_transf_41 PF13844.6 EKX37095.1 - 6.7e-38 130.3 2.2 1.5e-32 112.7 0.0 3.2 1 1 2 3 3 3 3 Glycosyl transferase family 41 TPR_11 PF13414.6 EKX37095.1 - 0.0046 16.6 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 TPR repeat TPR_16 PF13432.6 EKX37095.1 - 0.063 13.9 0.7 0.063 13.9 0.7 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1664 PF07889.12 EKX37096.1 - 0.0074 16.3 10.6 0.0074 16.3 10.6 7.4 4 3 2 7 7 7 4 Protein of unknown function (DUF1664) zf-ZPR1 PF03367.13 EKX37097.1 - 2.5e-31 108.7 0.0 3e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 ZPR1 zinc-finger domain Mpt_N PF09176.11 EKX37097.1 - 0.091 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal Rubredoxin_2 PF18073.1 EKX37097.1 - 0.11 12.2 0.3 0.18 11.5 0.3 1.3 1 0 0 1 1 1 0 Rubredoxin metal binding domain zf-ZPR1 PF03367.13 EKX37098.1 - 1.1e-42 145.6 0.0 1.2e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 ZPR1 zinc-finger domain ABC_membrane PF00664.23 EKX37099.1 - 4.2e-53 180.8 5.1 5.8e-53 180.3 5.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EKX37099.1 - 1e-33 116.7 0.0 2.6e-33 115.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EKX37099.1 - 1.9e-05 24.2 0.0 7.3e-05 22.3 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EKX37099.1 - 0.0011 18.6 0.8 0.0024 17.6 0.4 1.8 2 0 0 2 2 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 EKX37099.1 - 0.0019 17.9 0.6 0.98 9.1 0.1 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_16 PF13191.6 EKX37099.1 - 0.002 18.5 0.4 0.0078 16.6 0.4 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EKX37099.1 - 0.0031 17.8 1.0 0.099 12.9 1.0 2.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EKX37099.1 - 0.0077 16.7 1.7 0.14 12.6 0.3 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 EKX37099.1 - 0.009 15.9 0.1 0.029 14.3 0.1 1.9 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_30 PF13604.6 EKX37099.1 - 0.011 15.4 0.6 0.075 12.7 0.6 2.2 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EKX37099.1 - 0.057 13.4 0.4 1.7 8.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) 7tm_2 PF00002.24 EKX37099.1 - 0.062 12.6 0.9 4.3 6.6 0.3 2.2 2 0 0 2 2 2 0 7 transmembrane receptor (Secretin family) SbcCD_C PF13558.6 EKX37099.1 - 0.067 13.4 0.2 1.3 9.3 0.3 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 EKX37099.1 - 0.069 12.7 1.1 1.7 8.2 0.2 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EKX37099.1 - 0.073 13.0 0.2 2.9 7.8 0.1 2.4 2 0 0 2 2 2 0 NTPase AAA_23 PF13476.6 EKX37099.1 - 0.1 13.1 0.1 0.29 11.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 EKX37099.1 - 0.12 12.2 0.0 0.39 10.5 0.0 1.9 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF1367 PF07105.11 EKX37099.1 - 0.22 11.2 0.6 0.8 9.3 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1367) DUF3021 PF11457.8 EKX37099.1 - 1.9 8.8 5.8 2.3 8.5 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) ADP_ribosyl_GH PF03747.14 EKX37101.1 - 3e-36 125.7 0.4 3.4e-36 125.5 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase RsgA_GTPase PF03193.16 EKX37103.1 - 2.2e-31 109.0 0.0 3.1e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 EKX37103.1 - 1.1e-06 28.7 0.0 1.6e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EKX37103.1 - 2.9e-06 26.9 0.0 0.031 13.8 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA_16 PF13191.6 EKX37103.1 - 0.00017 22.0 0.0 0.00022 21.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 EKX37103.1 - 0.001 19.6 0.0 0.0013 19.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 EKX37103.1 - 0.0018 18.0 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Guanylate_kin PF00625.21 EKX37103.1 - 0.0039 16.9 0.0 0.022 14.4 0.0 2.1 1 1 0 1 1 1 1 Guanylate kinase AAA_22 PF13401.6 EKX37103.1 - 0.02 15.2 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 EKX37103.1 - 0.027 14.7 0.0 0.049 13.9 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 EKX37103.1 - 0.033 13.7 0.1 0.047 13.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 EKX37103.1 - 0.038 13.2 0.1 0.047 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Dynamin_N PF00350.23 EKX37103.1 - 0.04 14.0 0.1 0.092 12.8 0.1 1.6 1 0 0 1 1 1 0 Dynamin family ApbA PF02558.16 EKX37103.1 - 0.044 13.4 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Septin PF00735.18 EKX37103.1 - 0.056 12.7 0.0 0.075 12.3 0.0 1.4 1 1 0 1 1 1 0 Septin NACHT PF05729.12 EKX37103.1 - 0.086 12.7 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 NACHT domain Ras PF00071.22 EKX37103.1 - 0.091 12.4 0.1 0.4 10.3 0.1 2.0 1 1 1 2 2 2 0 Ras family AAA_15 PF13175.6 EKX37103.1 - 0.093 12.4 0.1 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 EKX37103.1 - 0.1 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AIG1 PF04548.16 EKX37103.1 - 0.12 11.7 0.2 0.17 11.2 0.2 1.2 1 0 0 1 1 1 0 AIG1 family IstB_IS21 PF01695.17 EKX37103.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_23 PF13476.6 EKX37103.1 - 0.13 12.8 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2813 PF11398.8 EKX37103.1 - 0.14 11.4 0.2 0.23 10.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) T2SSE PF00437.20 EKX37103.1 - 0.14 11.2 0.1 0.19 10.7 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_21 PF13304.6 EKX37103.1 - 0.17 11.7 0.1 0.23 11.2 0.1 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system MCM PF00493.23 EKX37103.1 - 0.17 10.9 0.1 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 MCM P-loop domain SGL PF08450.12 EKX37104.1 - 0.13 11.8 0.0 1 8.9 0.0 2.1 1 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region DUF2788 PF10981.8 EKX37105.1 - 0.068 13.2 0.3 0.1 12.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2788) ubiquitin PF00240.23 EKX37108.1 - 3.6e-56 186.8 3.6 9.3e-33 111.8 0.5 2.1 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 EKX37108.1 - 1.1e-26 92.4 2.9 1e-15 57.3 0.7 2.2 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like zf-AN1 PF01428.16 EKX37108.1 - 4.3e-08 33.2 14.6 7.8e-08 32.4 14.6 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger Ubiquitin_2 PF14560.6 EKX37108.1 - 4.8e-08 33.3 0.8 0.0011 19.4 0.1 3.2 2 2 0 2 2 2 2 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EKX37108.1 - 2.3e-06 27.7 0.1 0.038 14.1 0.1 2.6 2 1 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EKX37108.1 - 2.8e-06 27.6 0.4 0.035 14.4 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 EKX37108.1 - 6.8e-06 25.9 0.2 0.016 15.2 0.1 2.3 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 EKX37108.1 - 6.2e-05 23.5 0.1 0.09 13.3 0.0 2.2 1 1 0 2 2 2 2 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EKX37108.1 - 0.013 15.6 3.1 21 5.2 0.0 3.2 3 0 0 3 3 3 0 Ubiquitin-like domain DUF2870 PF11069.8 EKX37108.1 - 0.077 13.4 0.0 23 5.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) DUF969 PF06149.12 EKX37108.1 - 0.13 11.7 0.0 11 5.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF969) Pkinase PF00069.25 EKX37110.1 - 6.5e-46 156.8 0.0 8.8e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX37110.1 - 1.7e-26 93.1 0.0 2.4e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX37110.1 - 1.3e-06 28.0 0.0 2.3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RWP-RK PF02042.15 EKX37111.1 - 6.4e-14 51.7 0.0 1e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX37111.1 - 0.033 14.0 0.0 0.12 12.2 0.0 1.9 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family RWP-RK PF02042.15 EKX37112.1 - 7.9e-14 51.4 0.0 1.3e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX37112.1 - 0.044 13.6 0.0 0.15 11.9 0.0 1.8 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family Pex19 PF04614.12 EKX37113.1 - 6.3e-17 62.2 0.3 1.2e-16 61.3 0.0 1.5 2 0 0 2 2 2 1 Pex19 protein family Peptidase_M13_N PF05649.13 EKX37114.1 - 9.2e-76 256.0 0.1 5.5e-45 154.7 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M13 Peptidase_M13 PF01431.21 EKX37114.1 - 4.3e-53 180.0 0.0 8.4e-53 179.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M13 DnaJ PF00226.31 EKX37115.1 - 1.1e-13 51.1 0.4 2.8e-13 49.8 0.4 1.6 1 0 0 1 1 1 1 DnaJ domain DUF3818 PF12825.7 EKX37115.1 - 0.44 9.5 3.7 0.85 8.6 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) ATP-synt_E PF05680.12 EKX37117.1 - 2.5 8.5 7.5 1.6 9.1 3.0 2.3 2 1 0 2 2 2 0 ATP synthase E chain PKD_channel PF08016.12 EKX37118.1 - 2.2e-25 89.2 21.6 4.1e-18 65.3 9.1 2.7 2 0 0 2 2 2 2 Polycystin cation channel C2 PF00168.30 EKX37118.1 - 8.9e-17 61.3 0.0 2.1e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain Ion_trans PF00520.31 EKX37118.1 - 1.4e-12 47.4 17.0 4.1e-12 45.9 16.8 1.9 1 1 0 1 1 1 1 Ion transport protein Ephrin_rec_like PF07699.13 EKX37118.1 - 5.6e-08 32.4 29.9 1.1e-05 25.0 6.8 5.0 3 1 0 3 3 3 3 Putative ephrin-receptor like EF-hand_1 PF00036.32 EKX37118.1 - 0.0098 15.4 0.5 0.033 13.7 0.5 1.9 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 EKX37118.1 - 0.021 14.3 0.2 0.051 13.1 0.2 1.7 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 EKX37118.1 - 0.077 13.0 0.1 0.23 11.5 0.1 1.8 1 0 0 1 1 1 0 EF-hand domain ApoLp-III PF07464.11 EKX37119.1 - 0.0012 18.9 0.6 0.0019 18.3 0.6 1.2 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) IL10 PF00726.17 EKX37119.1 - 0.12 11.9 0.1 0.37 10.3 0.0 1.8 1 1 1 2 2 2 0 Interleukin 10 Got1 PF04178.12 EKX37120.1 - 0.38 11.2 8.8 0.08 13.4 1.3 2.5 3 0 0 3 3 3 0 Got1/Sft2-like family Kelch_1 PF01344.25 EKX37121.1 - 1.9e-60 200.2 0.4 5.4e-12 45.1 0.0 6.1 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 EKX37121.1 - 4.2e-39 131.6 6.2 1.5e-08 34.6 0.0 6.2 2 2 4 6 6 6 6 Kelch motif Kelch_5 PF13854.6 EKX37121.1 - 2e-25 88.3 6.9 0.00011 22.0 0.0 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EKX37121.1 - 2.6e-23 81.0 0.0 0.013 15.5 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EKX37121.1 - 5.7e-21 74.3 0.6 0.00046 20.1 0.0 6.5 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EKX37121.1 - 2.3e-20 72.4 0.2 0.0028 17.9 0.0 6.1 6 0 0 6 6 6 4 Galactose oxidase, central domain Herpes_UL49_2 PF04823.12 EKX37121.1 - 0.13 12.4 0.2 1.9 8.6 0.0 2.7 3 0 0 3 3 3 0 Herpesvirus UL49 tegument protein DUF1744 PF08490.12 EKX37122.1 - 1.2e-80 271.1 0.1 2.1e-80 270.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 EKX37122.1 - 1.6e-70 237.9 1.7 1.6e-70 237.9 1.7 2.5 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EKX37122.1 - 1.3e-12 47.2 0.7 3.8e-11 42.4 0.7 3.1 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 EKX37122.1 - 4.2e-08 33.1 0.7 1.2e-07 31.7 0.1 2.1 2 0 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EKX37122.1 - 0.00011 22.2 0.7 0.00047 20.2 0.0 2.5 3 0 0 3 3 3 1 RNase_H superfamily Patatin PF01734.22 EKX37123.1 - 7.7e-21 75.2 0.1 2e-20 73.9 0.1 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase LRR_8 PF13855.6 EKX37123.1 - 3.8e-13 49.0 4.5 3.8e-13 49.0 4.5 2.3 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 EKX37123.1 - 2.1e-09 37.5 14.7 3.6e-06 27.2 3.1 3.8 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX37123.1 - 0.00089 19.2 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EKX37123.1 - 0.0015 18.8 13.0 0.16 12.7 0.9 4.5 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_9 PF14580.6 EKX37123.1 - 0.11 12.0 0.4 0.29 10.6 0.4 1.7 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 EKX37123.1 - 5.9 7.2 11.5 25 5.2 0.1 4.7 4 0 0 4 4 4 0 Leucine Rich repeat Abhydrolase_3 PF07859.13 EKX37124.1 - 4e-12 46.4 0.0 1.4e-11 44.7 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EKX37124.1 - 2.6e-06 27.1 0.0 0.014 14.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EKX37124.1 - 4.7e-06 26.0 0.0 0.057 12.7 0.0 3.1 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EKX37124.1 - 6.1e-05 23.7 0.0 0.00014 22.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.28 EKX37124.1 - 0.0005 19.1 0.0 0.0014 17.6 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family LIDHydrolase PF10230.9 EKX37124.1 - 0.0033 17.0 0.0 0.0059 16.2 0.0 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Say1_Mug180 PF10340.9 EKX37124.1 - 0.024 13.5 0.0 0.034 13.0 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase Thioesterase PF00975.20 EKX37124.1 - 0.046 13.8 0.0 0.074 13.2 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain RWP-RK PF02042.15 EKX37125.1 - 3.8e-15 55.6 0.1 6.3e-15 54.9 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain PARP PF00644.20 EKX37126.1 - 1.2e-06 28.2 0.0 2.4e-06 27.3 0.0 1.5 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Pkinase_Tyr PF07714.17 EKX37127.1 - 3.9e-27 95.2 0.0 4.7e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX37127.1 - 2.7e-24 86.0 0.0 3.2e-24 85.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EKX37127.1 - 0.019 14.4 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EKX37127.1 - 0.052 12.9 0.0 0.075 12.3 0.0 1.5 1 1 0 1 1 1 0 Kinase-like WD40 PF00400.32 EKX37128.1 - 2.1e-54 180.2 23.3 1.8e-10 41.2 0.7 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX37128.1 - 7e-32 109.6 11.3 9.5e-09 35.4 0.1 6.9 1 1 6 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EKX37128.1 - 2e-08 33.3 2.9 0.029 13.0 0.0 5.3 1 1 4 6 6 6 2 Nucleoporin Nup120/160 eIF2A PF08662.11 EKX37128.1 - 5.3e-08 33.0 1.3 0.0018 18.2 0.1 3.5 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EKX37128.1 - 4.1e-06 26.0 2.4 1.3 8.0 0.0 5.2 1 1 5 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EKX37128.1 - 6.2e-06 25.7 0.0 1.4 8.2 0.0 4.2 2 2 2 4 4 4 2 WD40-like domain PD40 PF07676.12 EKX37128.1 - 4.5e-05 23.3 0.1 18 5.4 0.0 6.4 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 EKX37128.1 - 9.1e-05 21.9 9.6 0.21 10.9 0.0 5.4 1 1 4 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Coatomer_WDAD PF04053.14 EKX37128.1 - 0.0067 15.5 0.6 0.84 8.6 0.3 3.3 1 1 2 3 3 3 1 Coatomer WD associated region MetallophosC PF16370.5 EKX37128.1 - 0.011 15.9 1.3 0.47 10.7 0.3 3.2 1 1 2 3 3 3 0 C terminal of Calcineurin-like phosphoesterase DUF5122 PF17164.4 EKX37128.1 - 0.048 14.0 1.2 5.9 7.3 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller IKI3 PF04762.12 EKX37128.1 - 0.097 10.7 11.8 0.096 10.7 0.8 2.6 1 1 1 2 2 2 0 IKI3 family Meleagrin PF08189.11 EKX37128.1 - 1.2 8.9 4.4 3.3 7.5 0.1 3.6 4 0 0 4 4 4 0 Meleagrin/Cygnin family PIN_2 PF10130.9 EKX37128.1 - 1.2 9.3 11.0 6.6 7.0 0.1 5.1 6 0 0 6 6 6 0 PIN domain DUF4082 PF13313.6 EKX37128.1 - 3.6 7.6 8.3 19 5.3 0.0 4.7 3 2 3 6 6 6 0 Domain of unknown function (DUF4082) WD40 PF00400.32 EKX37129.1 - 1.8e-29 101.4 6.7 3.5e-05 24.5 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX37129.1 - 7.8e-17 61.4 0.1 1.7e-06 28.3 0.1 5.3 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 EKX37129.1 - 1.9e-13 49.8 1.0 3.1e-13 49.1 0.1 1.9 2 0 0 2 2 2 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 EKX37129.1 - 1.7e-07 30.5 0.4 0.54 9.2 0.0 4.4 2 1 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EKX37129.1 - 7.2e-05 22.8 0.0 0.11 12.3 0.0 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 EKX37129.1 - 0.0031 17.4 0.0 0.0075 16.2 0.0 1.6 1 0 0 1 1 1 1 LisH Nup160 PF11715.8 EKX37129.1 - 0.019 13.6 0.0 1.3 7.6 0.0 2.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PD40 PF07676.12 EKX37129.1 - 0.089 12.8 0.0 2.8 8.0 0.0 3.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Hira PF07569.11 EKX37129.1 - 0.1 12.3 0.4 6 6.5 0.0 3.3 5 0 0 5 5 5 0 TUP1-like enhancer of split PDZ_6 PF17820.1 EKX37130.1 - 5.1e-05 23.0 0.5 0.00012 21.8 0.1 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX37130.1 - 0.00063 20.0 0.2 0.0026 18.0 0.0 2.1 2 1 1 3 3 3 1 PDZ domain PDZ PF00595.24 EKX37130.1 - 0.023 15.1 0.3 0.088 13.2 0.0 2.0 2 0 0 2 2 2 0 PDZ domain DUF1523 PF07509.11 EKX37130.1 - 0.16 11.3 0.2 0.35 10.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1523) PTPRCAP PF15713.5 EKX37131.1 - 0.52 10.6 14.1 0.38 11.0 8.3 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Cytomega_UL84 PF06284.11 EKX37131.1 - 1 7.7 3.9 1.4 7.3 3.9 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Mito_fiss_Elm1 PF06258.11 EKX37132.1 - 6.9e-48 163.4 0.0 9.7e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial fission ELM1 Zn_clus PF00172.18 EKX37133.1 - 3.5e-14 52.6 25.4 9.1e-09 35.3 8.9 2.8 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 EKX37133.1 - 0.00063 20.5 0.7 3.1 8.8 0.1 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat WD40 PF00400.32 EKX37134.1 - 4.9e-21 74.6 15.8 0.00047 20.9 0.0 7.6 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX37134.1 - 1.2e-09 38.3 0.7 0.0066 16.7 0.0 5.1 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 EKX37134.1 - 0.05 11.9 0.0 5.4 5.2 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz GerD PF17898.1 EKX37135.1 - 0.0018 18.2 0.6 0.0072 16.3 0.6 2.1 1 1 0 1 1 1 1 Spore germination GerD central core domain bZIP_1 PF00170.21 EKX37135.1 - 3.3 7.9 6.4 1.8 8.7 0.6 2.8 2 0 0 2 2 2 0 bZIP transcription factor Rotamase PF00639.21 EKX37136.1 - 1.5e-21 77.2 0.1 1.8e-21 76.9 0.1 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EKX37136.1 - 2.3e-17 63.6 0.1 3.6e-17 63.0 0.1 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 EKX37136.1 - 2.8e-06 28.1 0.0 3.7e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain X8 PF07983.13 EKX37136.1 - 0.037 14.7 0.0 0.051 14.3 0.0 1.2 1 0 0 1 1 1 0 X8 domain MscS_porin PF12795.7 EKX37137.1 - 0.00033 20.3 5.1 0.00055 19.6 5.1 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain FlxA PF14282.6 EKX37137.1 - 0.0018 18.2 2.8 0.066 13.2 0.3 2.5 2 0 0 2 2 2 1 FlxA-like protein HrpB7 PF09486.10 EKX37137.1 - 0.0047 17.3 1.8 0.0047 17.3 1.8 2.3 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB7) Lebercilin PF15619.6 EKX37137.1 - 0.015 14.9 13.8 0.024 14.3 8.0 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease TACC_C PF05010.14 EKX37137.1 - 0.032 14.0 11.3 0.26 11.1 0.3 2.3 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal GrpE PF01025.19 EKX37137.1 - 0.053 13.2 3.3 0.28 10.8 1.6 2.2 2 0 0 2 2 2 0 GrpE HALZ PF02183.18 EKX37137.1 - 0.053 13.7 0.2 0.053 13.7 0.2 2.3 3 0 0 3 3 1 0 Homeobox associated leucine zipper IFP_35_N PF07334.13 EKX37137.1 - 0.059 13.5 4.3 0.64 10.1 0.2 2.6 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus PRKG1_interact PF15898.5 EKX37137.1 - 0.078 13.9 12.6 3.3 8.7 0.1 2.8 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF1131 PF06572.12 EKX37137.1 - 0.081 12.6 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1131) FliJ PF02050.16 EKX37137.1 - 0.14 12.4 8.8 0.65 10.2 5.0 2.4 2 0 0 2 2 2 0 Flagellar FliJ protein HMMR_N PF15905.5 EKX37137.1 - 0.15 11.5 11.0 0.48 9.8 10.9 1.8 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF4140 PF13600.6 EKX37137.1 - 0.15 12.5 6.7 1.6 9.2 0.5 2.9 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) HR1 PF02185.16 EKX37137.1 - 0.2 11.8 0.2 0.2 11.8 0.2 3.2 3 0 0 3 3 3 0 Hr1 repeat Seryl_tRNA_N PF02403.22 EKX37137.1 - 0.38 11.0 4.8 1.2 9.3 0.1 2.9 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 EKX37137.1 - 0.47 9.8 8.2 4.5 6.5 8.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ATG16 PF08614.11 EKX37137.1 - 0.55 10.4 12.4 0.074 13.3 0.9 2.7 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) OrfB_IS605 PF01385.19 EKX37137.1 - 0.61 10.3 4.3 1.1 9.6 0.7 2.6 2 1 0 2 2 2 0 Probable transposase FapA PF03961.13 EKX37137.1 - 0.74 8.3 7.4 0.27 9.8 3.9 1.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A GldM_N PF12081.8 EKX37137.1 - 1 9.4 4.0 1.4 9.0 0.2 2.4 1 1 0 2 2 2 0 GldM N-terminal domain TPR_MLP1_2 PF07926.12 EKX37137.1 - 1.4 9.0 15.7 47 4.0 0.2 3.3 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Syntaxin-6_N PF09177.11 EKX37137.1 - 1.5 9.4 7.4 3.3 8.3 1.8 3.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF1192 PF06698.11 EKX37137.1 - 1.6 8.8 5.8 0.69 10.0 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DivIVA PF05103.13 EKX37137.1 - 2.3 8.3 10.0 0.8 9.8 0.1 3.3 2 1 1 3 3 3 0 DivIVA protein TMF_DNA_bd PF12329.8 EKX37137.1 - 3.2 7.8 17.0 2 8.5 1.3 4.0 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 EKX37137.1 - 4 7.3 8.6 17 5.2 1.6 3.1 3 0 0 3 3 3 0 Septum formation initiator Cep57_CLD PF14073.6 EKX37137.1 - 4.5 7.3 15.1 7.2 6.6 10.4 2.8 2 1 0 2 2 2 0 Centrosome localisation domain of Cep57 GreA_GreB_N PF03449.15 EKX37137.1 - 4.6 7.5 12.9 4.8 7.4 1.3 3.3 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal FAM76 PF16046.5 EKX37137.1 - 5.3 6.3 10.4 13 5.1 10.3 1.6 1 1 0 1 1 1 0 FAM76 protein CC2-LZ PF16516.5 EKX37137.1 - 5.7 7.4 13.6 0.68 10.3 1.7 3.3 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator ZapB PF06005.12 EKX37137.1 - 5.8 7.4 14.7 8.7 6.9 1.2 3.4 3 0 0 3 3 3 0 Cell division protein ZapB DUF3461 PF11944.8 EKX37137.1 - 5.8 7.1 9.3 4 7.6 3.8 2.7 3 1 0 3 3 2 0 Protein of unknown function (DUF3461) bZIP_2 PF07716.15 EKX37137.1 - 8.7 6.5 13.6 2.4 8.3 1.1 2.8 3 0 0 3 3 2 0 Basic region leucine zipper DUF3040 PF11239.8 EKX37138.1 - 2.1 8.7 7.5 0.75 10.1 1.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Rad51 PF08423.11 EKX37139.1 - 4.4e-09 36.0 0.7 0.0012 18.1 0.1 2.1 1 1 0 2 2 2 2 Rad51 AAA_25 PF13481.6 EKX37139.1 - 0.0085 15.7 0.1 4.1 6.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF2996 PF11210.8 EKX37139.1 - 0.034 14.6 0.0 0.07 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2996) ATPase PF06745.13 EKX37139.1 - 0.12 11.7 0.1 7.7 5.8 0.0 2.2 2 0 0 2 2 2 0 KaiC LRR_6 PF13516.6 EKX37140.1 - 3.6e-20 70.3 12.6 0.0036 17.2 0.1 6.1 6 0 0 6 6 6 6 Leucine Rich repeat LRR_1 PF00560.33 EKX37140.1 - 1.1e-07 31.4 5.2 17 6.5 0.0 6.1 5 1 0 5 5 5 4 Leucine Rich Repeat LRR_8 PF13855.6 EKX37140.1 - 0.00045 19.9 12.3 0.67 9.8 1.5 4.9 2 2 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 EKX37140.1 - 0.048 14.1 12.9 0.48 10.9 1.3 4.2 2 1 3 5 5 5 0 Leucine Rich repeats (2 copies) TTL PF03133.15 EKX37141.1 - 0.16 11.1 0.0 0.38 9.8 0.0 1.6 1 1 1 2 2 2 0 Tubulin-tyrosine ligase family ESCRT-II PF05871.12 EKX37143.1 - 4.1e-50 169.7 0.1 5e-50 169.4 0.1 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit DUF2064 PF09837.9 EKX37143.1 - 0.011 15.6 0.0 0.026 14.3 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) DUF3752 PF12572.8 EKX37144.1 - 0.017 15.7 1.0 0.037 14.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) ELM2 PF01448.24 EKX37144.1 - 0.09 13.5 0.0 0.25 12.1 0.0 1.7 1 0 0 1 1 1 0 ELM2 domain Ank_4 PF13637.6 EKX37145.1 - 1.9e-10 41.1 0.2 4.4e-06 27.1 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX37145.1 - 4.6e-08 33.2 1.8 1.1e-05 25.6 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 EKX37145.1 - 5.4e-08 33.3 0.4 2.8e-07 31.0 0.1 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX37145.1 - 6.4e-06 26.1 1.2 0.0023 18.3 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EKX37145.1 - 7.4e-05 23.0 0.0 0.00022 21.4 0.1 1.8 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Nucleotid_trans PF03407.16 EKX37146.1 - 4.8e-14 52.8 0.0 1.1e-13 51.7 0.0 1.7 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Methyltransf_25 PF13649.6 EKX37146.1 - 5.5e-09 36.6 0.0 1.8e-08 35.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX37146.1 - 9.1e-09 35.9 0.0 3.2e-08 34.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX37146.1 - 7.8e-07 29.1 0.0 2.1e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX37146.1 - 9.6e-05 23.1 0.0 0.00021 22.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Glyco_hydro_43 PF04616.14 EKX37146.1 - 0.0017 17.7 0.2 0.15 11.3 0.1 3.3 3 1 1 4 4 4 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 EKX37146.1 - 0.0027 17.3 0.0 0.26 10.8 0.0 2.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Methyltransf_31 PF13847.6 EKX37146.1 - 0.16 11.7 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Collagen PF01391.18 EKX37149.1 - 4.9e-22 77.5 87.1 8.1e-10 38.3 23.6 4.4 3 1 2 5 5 5 3 Collagen triple helix repeat (20 copies) CytB6-F_Fe-S PF08802.10 EKX37149.1 - 0.14 12.2 2.8 0.28 11.2 2.8 1.5 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit Neur_chan_memb PF02932.16 EKX37151.1 - 0.00026 21.1 7.1 0.00026 21.1 7.1 1.7 2 0 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region THUMP PF02926.17 EKX37151.1 - 0.048 13.8 0.0 0.066 13.3 0.0 1.3 1 0 0 1 1 1 0 THUMP domain S1FA PF04689.13 EKX37151.1 - 0.095 12.9 0.0 0.095 12.9 0.0 2.4 3 0 0 3 3 3 0 DNA binding protein S1FA AAA_12 PF13087.6 EKX37153.1 - 6e-23 81.5 0.9 6.4e-23 81.4 0.9 1.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EKX37153.1 - 1.5e-08 34.3 0.0 1.8e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EKX37153.1 - 9.9e-08 32.0 0.0 1e-07 31.9 0.0 1.0 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase UvrD_C PF13361.6 EKX37153.1 - 1.8e-05 24.3 0.0 2.1e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Vasohibin PF14822.6 EKX37153.1 - 0.0041 16.4 0.0 0.0041 16.4 0.0 1.0 1 0 0 1 1 1 1 Vasohibin MORN PF02493.20 EKX37155.1 - 7.7e-30 101.0 87.3 1.9e-05 24.3 0.6 12.4 13 0 0 13 13 13 10 MORN repeat PA PF02225.22 EKX37156.1 - 6.8e-09 35.6 0.0 1.2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 PA domain adh_short_C2 PF13561.6 EKX37157.1 - 3.6e-45 154.4 0.1 4.2e-41 141.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EKX37157.1 - 1.8e-09 37.4 0.3 1.6e-06 27.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase Ribosomal_L21e PF01157.18 EKX37159.1 - 1.9e-43 146.4 2.3 1.9e-43 146.4 2.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L21e Mtc PF03820.17 EKX37160.1 - 3.5e-133 443.5 1.0 3.9e-133 443.3 1.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Ephrin_rec_like PF07699.13 EKX37161.1 - 1.9e-76 251.6 343.5 1.7e-07 30.9 6.5 35.7 23 8 13 36 36 36 31 Putative ephrin-receptor like BRE1 PF08647.11 EKX37162.1 - 0.017 15.2 0.5 0.017 15.2 0.5 3.2 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase YabA PF06156.13 EKX37162.1 - 0.1 13.3 11.2 0.23 12.1 0.4 3.3 2 1 1 3 3 3 0 Initiation control protein YabA DXP_reductoisom PF02670.16 EKX37162.1 - 0.28 11.9 1.4 0.96 10.2 0.3 2.3 2 1 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Sec34 PF04136.15 EKX37162.1 - 0.65 9.9 8.6 2 8.3 0.5 3.3 2 1 1 3 3 3 0 Sec34-like family CENP-F_leu_zip PF10473.9 EKX37162.1 - 0.88 9.6 31.0 2.4 8.2 2.7 3.1 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 EKX37162.1 - 7.3 6.7 19.8 2.8 8.0 1.4 3.4 3 2 1 4 4 4 0 Afadin- and alpha -actinin-Binding zf-C2H2_jaz PF12171.8 EKX37163.1 - 2.2e-07 31.0 3.0 3.7e-07 30.2 3.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EKX37163.1 - 3e-06 27.4 4.0 5e-06 26.7 4.0 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 EKX37163.1 - 0.00084 19.1 0.7 0.0016 18.2 0.7 1.4 1 0 0 1 1 1 1 U1 zinc finger UNC-79 PF14776.6 EKX37163.1 - 0.15 10.8 2.2 0.22 10.2 2.2 1.2 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 SURF2 PF05477.11 EKX37163.1 - 1.2 8.8 18.4 0.012 15.3 8.1 2.2 1 1 0 2 2 2 0 Surfeit locus protein 2 (SURF2) Ribosomal_L36e PF01158.18 EKX37163.1 - 1.4 9.2 10.3 0.16 12.2 4.9 2.1 2 1 0 2 2 2 0 Ribosomal protein L36e Ank_5 PF13857.6 EKX37164.1 - 3.8e-11 43.0 0.1 6.5e-11 42.3 0.1 1.4 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX37164.1 - 5.2e-11 42.8 0.8 2e-05 25.0 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX37164.1 - 6.6e-10 39.4 0.1 7.3e-10 39.3 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX37164.1 - 8.8e-10 38.6 3.2 1e-07 32.0 0.2 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EKX37164.1 - 2.9e-09 36.4 0.4 1.2e-07 31.4 0.1 2.5 3 0 0 3 3 3 1 Ankyrin repeat PP2C PF00481.21 EKX37165.1 - 1.4e-42 146.1 0.0 1.8e-42 145.8 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EKX37165.1 - 3.5e-05 23.5 0.1 0.00015 21.4 0.1 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EKX37165.1 - 4.6e-05 23.4 0.1 0.29 11.0 0.0 2.0 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) AF-4 PF05110.13 EKX37166.1 - 0.031 12.4 42.4 0.063 11.4 42.4 1.4 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PUF PF00806.19 EKX37168.1 - 6.2e-51 167.3 17.2 5.5e-09 35.2 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF3825 PF12873.7 EKX37168.1 - 0.068 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) DUF4349 PF14257.6 EKX37169.1 - 5.7e-06 25.9 12.1 1.1e-05 25.0 12.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) NumbF PF06311.12 EKX37169.1 - 0.018 15.6 2.5 0.052 14.1 2.5 1.8 1 0 0 1 1 1 0 NUMB domain SCVP PF17619.2 EKX37169.1 - 0.038 14.8 3.4 10 7.1 2.2 3.4 1 1 1 2 2 2 0 Secreted clade V proteins TMF_DNA_bd PF12329.8 EKX37169.1 - 1 9.4 30.1 0.044 13.8 12.6 3.6 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding Laminin_II PF06009.12 EKX37169.1 - 1.1 9.2 12.9 0.093 12.7 6.4 2.1 1 1 1 2 2 2 0 Laminin Domain II CENP-F_leu_zip PF10473.9 EKX37169.1 - 1.3 9.1 39.1 0.69 9.9 22.2 2.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 EKX37169.1 - 1.3 9.5 30.2 0.33 11.4 16.2 2.2 1 1 1 2 2 2 0 Fez1 zf-C4H2 PF10146.9 EKX37169.1 - 2.9 8.2 27.6 27 5.0 27.6 2.1 1 1 0 1 1 1 0 Zinc finger-containing protein TMF_TATA_bd PF12325.8 EKX37169.1 - 4.5 7.5 31.7 0.96 9.7 14.3 3.3 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Ribosomal_S7e PF01251.18 EKX37172.1 - 3.5e-35 121.4 0.8 4.2e-35 121.2 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S7e ATPgrasp_YheCD PF14398.6 EKX37172.1 - 0.027 13.7 0.0 0.057 12.7 0.0 1.5 1 0 0 1 1 1 0 YheC/D like ATP-grasp Ribosomal_S7e PF01251.18 EKX37173.1 - 5e-35 120.9 0.8 6.1e-35 120.6 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S7e ATPgrasp_YheCD PF14398.6 EKX37173.1 - 0.033 13.4 0.0 0.068 12.4 0.0 1.5 1 0 0 1 1 1 0 YheC/D like ATP-grasp PRK PF00485.18 EKX37174.1 - 1.6e-12 47.6 0.1 1.1e-10 41.6 0.1 2.3 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AP_endonuc_2 PF01261.24 EKX37174.1 - 0.037 13.5 0.1 0.053 12.9 0.1 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel TFIIA PF03153.13 EKX37175.1 - 0.00044 20.4 44.1 0.00067 19.8 44.1 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 EKX37175.1 - 0.011 16.4 23.7 0.011 16.4 23.7 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MRNIP PF15749.5 EKX37175.1 - 0.083 13.6 0.7 0.083 13.6 0.7 2.3 2 0 0 2 2 2 0 MRN-interacting protein SpoIIP PF07454.11 EKX37175.1 - 0.13 11.7 23.2 0.58 9.6 14.6 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF2052 PF09747.9 EKX37175.1 - 0.19 11.8 28.8 0.11 12.6 5.3 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) FAM176 PF14851.6 EKX37175.1 - 0.22 11.2 21.1 0.24 11.1 3.7 2.3 2 0 0 2 2 2 0 FAM176 family PTPRCAP PF15713.5 EKX37175.1 - 0.41 10.9 33.6 0.63 10.3 7.3 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated BSP_II PF05432.11 EKX37175.1 - 0.59 9.8 22.2 0.12 12.1 7.7 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) CPSF100_C PF13299.6 EKX37175.1 - 0.61 10.3 22.3 2.2 8.4 1.1 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal FYDLN_acid PF09538.10 EKX37175.1 - 1.5 9.6 20.4 4.5 8.0 6.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF2457 PF10446.9 EKX37175.1 - 1.5 7.9 31.0 1.7 7.7 11.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) DUF3807 PF12720.7 EKX37175.1 - 1.6 8.9 30.9 1.3 9.2 20.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Eapp_C PF10238.9 EKX37175.1 - 2 8.5 23.2 0.73 9.9 12.7 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein Tim54 PF11711.8 EKX37175.1 - 2.1 7.1 27.5 0.63 8.8 13.4 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF4471 PF14740.6 EKX37175.1 - 2.9 7.1 16.3 5.6 6.1 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) DUF3391 PF11871.8 EKX37175.1 - 3.7 8.1 21.0 4.5 7.8 9.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Pox_Ag35 PF03286.14 EKX37175.1 - 3.9 7.2 25.4 0.55 10.0 8.7 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein FAM60A PF15396.6 EKX37175.1 - 4.2 7.3 18.1 16 5.5 0.2 2.2 2 0 0 2 2 2 0 Protein Family FAM60A EFTUD2 PF16004.5 EKX37175.1 - 4.2 8.0 28.5 1.2 9.7 14.6 2.5 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus CDC45 PF02724.14 EKX37175.1 - 4.4 5.5 30.5 0.67 8.2 4.7 2.0 2 0 0 2 2 2 0 CDC45-like protein XAP5 PF04921.14 EKX37175.1 - 6.8 6.4 23.6 4 7.2 2.6 2.1 2 0 0 2 2 2 0 XAP5, circadian clock regulator DUF572 PF04502.13 EKX37175.1 - 7.3 6.1 24.2 1.1 8.8 1.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) DnaJ PF00226.31 EKX37176.1 - 2.6e-14 53.1 0.1 5.5e-14 52.0 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Mito_carr PF00153.27 EKX37178.1 - 4.9e-24 84.1 0.1 7.7e-20 70.6 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF1323 PF07037.11 EKX37178.1 - 0.11 12.8 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative transcription regulator (DUF1323) DSPn PF14671.6 EKX37179.1 - 3.6e-27 95.5 0.2 1.8e-26 93.3 0.0 2.2 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EKX37179.1 - 1.6e-14 53.8 0.0 6.2e-14 51.9 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX37179.1 - 6.3e-05 22.6 0.0 9.6e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX37179.1 - 0.00022 21.4 0.0 0.00045 20.4 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EKX37179.1 - 0.0097 15.9 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family LOH1CR12 PF10158.9 EKX37180.1 - 0.13 12.3 3.0 0.22 11.5 2.4 1.7 1 1 0 1 1 1 0 Tumour suppressor protein ABA_GPCR PF12430.8 EKX37181.1 - 3.5e-34 118.1 12.8 3.5e-34 118.1 12.8 2.4 2 1 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 EKX37181.1 - 9.6e-18 64.0 0.1 2.9e-17 62.5 0.1 1.9 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal K-box PF01486.17 EKX37181.1 - 0.0071 16.5 5.1 0.052 13.7 0.3 2.3 2 0 0 2 2 2 2 K-box region CTP_transf_1 PF01148.20 EKX37182.1 - 0.007 16.2 9.1 0.014 15.1 9.1 1.6 1 1 0 1 1 1 1 Cytidylyltransferase family DSPc PF00782.20 EKX37183.1 - 8.8e-07 28.8 0.0 1.2e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain SOCS_box PF07525.16 EKX37183.1 - 0.024 15.0 0.8 0.049 14.0 0.8 1.5 1 0 0 1 1 1 0 SOCS box TFIID-18kDa PF02269.16 EKX37184.1 - 4.9e-13 48.9 7.1 1.2e-11 44.4 0.8 2.7 2 1 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit TctC PF03401.14 EKX37184.1 - 0.0034 16.5 0.6 0.0046 16.1 0.6 1.1 1 0 0 1 1 1 1 Tripartite tricarboxylate transporter family receptor DUF4633 PF15464.6 EKX37184.1 - 0.35 11.0 6.1 0.55 10.4 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) Med15 PF09606.10 EKX37184.1 - 3.1 6.4 27.8 3.4 6.2 27.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.13 EKX37184.1 - 4.4 7.2 17.7 5.7 6.8 17.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ank_4 PF13637.6 EKX37185.1 - 3.2e-20 72.2 1.6 4.8e-13 49.3 0.1 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX37185.1 - 5.3e-17 61.7 0.2 8.3e-09 35.6 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX37185.1 - 5.3e-15 55.1 0.5 6.5e-07 29.5 0.2 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EKX37185.1 - 1.4e-14 54.5 0.0 1.6e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX37185.1 - 1.2e-11 43.7 0.0 5.4e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat SHIPPO-rpt PF07004.12 EKX37186.1 - 8.9e-24 83.3 35.0 8.6e-05 23.3 2.9 7.1 6 1 0 6 6 6 6 Sperm-tail PG-rich repeat CS PF04969.16 EKX37187.1 - 1.4e-13 51.6 0.0 2e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 CS domain RWP-RK PF02042.15 EKX37188.1 - 1.4e-15 56.9 0.1 2.3e-15 56.3 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain TRCF PF03461.15 EKX37189.1 - 0.0016 18.8 34.9 7.5 7.0 0.4 7.4 1 1 5 6 6 6 5 TRCF domain UPAR_LY6_2 PF16975.5 EKX37189.1 - 0.013 15.7 5.8 89 3.4 5.8 4.0 1 1 0 1 1 1 0 Ly6/PLAUR domain-containing protein 6, Lypd6 TPR_2 PF07719.17 EKX37191.1 - 4.5e-09 35.7 7.5 0.21 11.8 0.0 6.1 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX37191.1 - 1.1e-07 31.4 11.2 0.071 13.0 0.1 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX37191.1 - 2.8e-05 24.5 3.3 0.096 13.6 0.1 5.1 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX37191.1 - 0.00019 21.4 7.3 0.2 12.0 0.1 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX37191.1 - 0.00059 20.4 0.3 62 4.4 0.0 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 EKX37191.1 - 0.002 18.2 1.8 0.94 9.7 0.1 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat Tmemb_9 PF05434.11 EKX37191.1 - 0.01 15.7 0.2 0.017 15.0 0.2 1.4 1 0 0 1 1 1 0 TMEM9 TPR_12 PF13424.6 EKX37191.1 - 0.022 15.1 4.9 0.95 9.8 0.0 4.4 5 1 0 5 5 5 0 Tetratricopeptide repeat Baculo_11_kDa PF06143.11 EKX37191.1 - 0.03 13.9 2.5 0.058 13.0 2.5 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family Sarcoglycan_1 PF04790.13 EKX37191.1 - 0.032 13.6 1.1 0.049 13.0 1.1 1.3 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein Wzy_C PF04932.15 EKX37191.1 - 0.043 13.5 0.1 0.067 12.8 0.1 1.2 1 0 0 1 1 1 0 O-Antigen ligase TPR_10 PF13374.6 EKX37191.1 - 0.069 13.0 10.0 3 7.8 0.1 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat HemY_N PF07219.13 EKX37191.1 - 1.9 8.7 7.6 0.72 10.1 3.0 2.5 2 1 1 3 3 3 0 HemY protein N-terminus Peptidase_M24 PF00557.24 EKX37192.1 - 1e-44 152.8 0.1 1.2e-44 152.5 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AA_permease_2 PF13520.6 EKX37193.1 - 4e-43 147.8 36.2 5.3e-43 147.4 36.2 1.1 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.21 EKX37194.1 - 0.39 10.7 2.5 0.7 9.9 2.5 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif SWIRM PF04433.17 EKX37195.1 - 6.5e-18 64.9 0.0 3.5e-17 62.5 0.0 2.3 2 0 0 2 2 2 1 SWIRM domain SAP30_Sin3_bdg PF13867.6 EKX37195.1 - 1.2e-06 28.7 0.1 2.9e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 AIF_C PF14721.6 EKX37195.1 - 0.1 12.9 0.3 0.1 12.9 0.3 5.9 5 1 1 6 6 6 0 Apoptosis-inducing factor, mitochondrion-associated, C-term LRR_8 PF13855.6 EKX37196.1 - 3.4e-25 87.6 26.4 3.3e-08 33.2 1.1 3.4 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EKX37196.1 - 1e-20 73.5 34.8 9.4e-05 22.7 0.1 5.2 1 1 6 7 7 7 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX37196.1 - 8.6e-07 28.6 9.3 0.00082 18.9 0.2 2.9 1 1 2 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 EKX37196.1 - 0.001 19.3 14.6 35 5.5 0.0 7.4 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.6 EKX37196.1 - 0.0017 18.2 13.7 2.9 8.2 0.1 6.4 6 0 0 6 6 6 2 Leucine Rich repeat Guanylate_cyc PF00211.20 EKX37197.1 - 1.1e-27 96.8 0.0 1.5e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 EKX37198.1 - 9e-24 84.1 0.1 1e-23 83.9 0.1 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Mpv17_PMP22 PF04117.12 EKX37199.1 - 3.8e-17 62.3 5.2 7.4e-17 61.3 5.2 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Lum_binding PF00677.17 EKX37200.1 - 4.3e-47 158.0 0.0 1.6e-22 79.3 0.0 2.2 2 0 0 2 2 2 2 Lumazine binding domain Imm65 PF15582.6 EKX37200.1 - 0.0086 15.0 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Immunity protein 65 DUF1798 PF08807.10 EKX37200.1 - 0.22 11.7 0.0 0.41 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) DUF4379 PF14311.6 EKX37202.1 - 5.1e-09 36.4 7.3 0.00044 20.6 1.5 2.8 2 0 0 2 2 2 2 Probable Zinc-ribbon domain Ppx-GppA PF02541.16 EKX37202.1 - 0.16 11.4 2.5 2.7 7.4 0.2 2.7 3 0 0 3 3 3 0 Ppx/GppA phosphatase family CLZ PF16526.5 EKX37203.1 - 0.00032 21.0 5.3 0.00032 21.0 5.3 3.2 2 1 1 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CENP-F_leu_zip PF10473.9 EKX37203.1 - 0.0004 20.4 38.6 0.043 13.9 21.6 2.1 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CALCOCO1 PF07888.11 EKX37203.1 - 0.0039 16.1 28.3 0.0046 15.9 28.3 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2353 PF09789.9 EKX37203.1 - 0.0043 16.5 21.2 0.0059 16.0 21.2 1.3 1 1 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) FapA PF03961.13 EKX37203.1 - 0.0049 15.5 18.7 0.0067 15.1 18.7 1.3 1 1 0 1 1 1 1 Flagellar Assembly Protein A DUF1640 PF07798.11 EKX37203.1 - 0.012 15.7 17.2 0.012 15.7 17.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) AKNA PF12443.8 EKX37203.1 - 0.024 15.3 4.7 0.024 15.3 4.7 2.7 1 1 1 2 2 2 0 AT-hook-containing transcription factor ABC_tran_CTD PF16326.5 EKX37203.1 - 0.026 14.8 14.9 0.026 14.8 14.9 3.1 1 1 2 3 3 3 0 ABC transporter C-terminal domain Tup_N PF08581.10 EKX37203.1 - 0.028 14.7 6.4 0.028 14.7 6.4 3.0 1 1 1 3 3 3 0 Tup N-terminal Tektin PF03148.14 EKX37203.1 - 0.035 12.9 22.1 0.35 9.6 9.5 2.6 1 1 1 2 2 2 0 Tektin family HOOK PF05622.12 EKX37203.1 - 0.037 12.2 25.4 0.047 11.8 25.4 1.2 1 0 0 1 1 1 0 HOOK protein TPR_MLP1_2 PF07926.12 EKX37203.1 - 0.046 13.8 32.0 0.65 10.1 10.7 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.12 EKX37203.1 - 0.048 14.1 7.9 2.7 8.5 0.1 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein GAS PF13851.6 EKX37203.1 - 0.053 12.9 32.5 2.7 7.3 12.6 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.8 EKX37203.1 - 0.093 10.2 26.0 0.11 10.0 26.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF5082 PF16888.5 EKX37203.1 - 0.11 12.8 22.7 0.075 13.3 4.0 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) DUF4164 PF13747.6 EKX37203.1 - 0.13 12.5 21.9 0.15 12.4 7.8 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) APG6_N PF17675.1 EKX37203.1 - 0.14 12.7 39.6 0.064 13.8 24.6 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region DegQ PF08181.11 EKX37203.1 - 0.15 12.2 0.4 0.15 12.2 0.4 3.3 1 1 2 3 3 3 0 DegQ (SacQ) family BRE1 PF08647.11 EKX37203.1 - 0.15 12.1 30.8 0.1 12.6 19.4 2.7 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Phage_GP20 PF06810.11 EKX37203.1 - 0.15 11.8 21.5 0.031 14.1 14.7 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 HIP1_clath_bdg PF16515.5 EKX37203.1 - 0.18 12.4 33.8 0.16 12.6 13.6 2.6 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ADIP PF11559.8 EKX37203.1 - 0.21 11.6 26.8 0.083 13.0 20.9 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 EKX37203.1 - 0.22 11.9 28.3 0.31 11.5 28.3 1.2 1 0 0 1 1 1 0 Fez1 Golgin_A5 PF09787.9 EKX37203.1 - 0.25 10.7 29.8 0.36 10.3 29.8 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF1664 PF07889.12 EKX37203.1 - 0.26 11.3 18.9 0.1 12.7 10.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ERM PF00769.19 EKX37203.1 - 0.29 10.9 37.3 2 8.2 37.3 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family FUSC-like PF12805.7 EKX37203.1 - 0.29 10.2 7.9 0.12 11.4 4.6 1.9 1 1 1 2 2 2 0 FUSC-like inner membrane protein yccS DUF4407 PF14362.6 EKX37203.1 - 0.32 10.3 20.5 0.083 12.2 9.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) dCache_3 PF14827.6 EKX37203.1 - 0.36 10.4 5.0 0.46 10.1 5.0 1.2 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase AAA_13 PF13166.6 EKX37203.1 - 0.37 9.4 19.1 0.53 8.9 19.1 1.3 1 0 0 1 1 1 0 AAA domain YabA PF06156.13 EKX37203.1 - 0.38 11.4 26.1 0.68 10.6 16.0 2.1 1 1 1 2 2 2 0 Initiation control protein YabA COG5 PF10392.9 EKX37203.1 - 0.4 10.9 10.9 0.54 10.4 8.3 2.3 1 1 0 2 2 1 0 Golgi transport complex subunit 5 Swi5 PF07061.11 EKX37203.1 - 0.41 10.8 22.9 0.23 11.6 4.0 3.1 1 1 1 2 2 2 0 Swi5 DivIC PF04977.15 EKX37203.1 - 0.48 10.2 26.8 0.096 12.5 1.4 3.7 2 1 2 4 4 4 0 Septum formation initiator UPF0242 PF06785.11 EKX37203.1 - 0.55 10.3 30.3 0.18 11.9 21.5 2.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 EKX37203.1 - 0.58 9.0 31.8 2.1 7.1 31.3 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein PEP-utilisers_N PF05524.13 EKX37203.1 - 0.62 10.2 11.4 11 6.3 11.3 2.4 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF3251 PF11622.8 EKX37203.1 - 0.66 9.6 6.7 1.3 8.6 2.6 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3251) TMPIT PF07851.13 EKX37203.1 - 0.73 9.0 21.2 0.038 13.2 14.6 1.8 1 1 1 2 2 2 0 TMPIT-like protein Seryl_tRNA_N PF02403.22 EKX37203.1 - 0.9 9.8 27.7 0.58 10.4 7.5 3.0 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF3450 PF11932.8 EKX37203.1 - 0.92 8.8 25.5 0.067 12.5 17.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4140 PF13600.6 EKX37203.1 - 0.95 9.9 20.8 1.8e+02 2.7 0.7 3.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) HU-CCDC81_bac_2 PF18175.1 EKX37203.1 - 1 9.3 11.4 0.097 12.6 4.8 2.6 2 2 2 4 4 3 0 CCDC81-like prokaryotic HU domain 2 End3 PF12761.7 EKX37203.1 - 1 9.5 22.9 0.16 12.1 18.9 1.7 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 HAUS-augmin3 PF14932.6 EKX37203.1 - 1 8.9 26.4 0.44 10.1 18.5 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 VPS38 PF17649.1 EKX37203.1 - 1 8.2 19.0 2.1 7.1 5.5 2.0 1 1 1 2 2 2 0 Vacuolar protein sorting 38 Lipoprotein_20 PF13942.6 EKX37203.1 - 1 9.2 18.0 3.2 7.6 10.3 2.2 1 1 1 2 2 2 0 YfhG lipoprotein ATG16 PF08614.11 EKX37203.1 - 1.1 9.5 30.8 0.13 12.5 24.6 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GOLGA2L5 PF15070.6 EKX37203.1 - 1.3 7.6 28.0 11 4.5 27.8 1.9 1 1 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Leu_zip PF15294.6 EKX37203.1 - 1.5 8.3 27.2 42 3.5 2.4 1.9 1 1 0 1 1 1 0 Leucine zipper Bacillus_HBL PF05791.11 EKX37203.1 - 1.9 8.3 14.6 0.16 11.8 8.3 1.9 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) SHE3 PF17078.5 EKX37203.1 - 2.3 7.9 25.9 0.44 10.2 17.8 2.1 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 TMF_TATA_bd PF12325.8 EKX37203.1 - 2.4 8.4 33.8 13 6.1 7.1 3.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding GrpE PF01025.19 EKX37203.1 - 2.4 7.8 29.5 2.8 7.6 10.3 2.1 1 1 1 2 2 2 0 GrpE Paralemmin PF03285.15 EKX37203.1 - 2.8 7.4 21.1 6.2 6.3 21.1 1.6 1 1 0 1 1 1 0 Paralemmin Exonuc_VII_L PF02601.15 EKX37203.1 - 2.8 7.4 15.8 4.7 6.7 15.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Laminin_II PF06009.12 EKX37203.1 - 3.1 7.8 17.9 2.6 8.1 12.5 2.6 1 1 1 2 2 2 0 Laminin Domain II HMMR_N PF15905.5 EKX37203.1 - 3.3 7.1 32.7 0.19 11.1 26.3 1.8 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal WDCP PF15390.6 EKX37203.1 - 3.7 5.8 11.7 4.1 5.7 11.7 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Uso1_p115_C PF04871.13 EKX37203.1 - 3.9 7.9 32.3 5.6e+02 0.9 32.2 2.3 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Cep57_MT_bd PF06657.13 EKX37203.1 - 4.3 7.9 22.3 2.1 8.9 7.4 2.7 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Sin3_corepress PF08295.12 EKX37203.1 - 4.4 7.4 14.3 0.1 12.7 2.5 2.7 2 1 0 3 3 3 0 Sin3 family co-repressor Fib_alpha PF08702.10 EKX37203.1 - 4.6 7.4 19.4 2.6 8.2 5.4 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Atg14 PF10186.9 EKX37203.1 - 5.3 6.0 22.8 7.4 5.6 22.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 THOC7 PF05615.13 EKX37203.1 - 5.6 7.2 26.9 0.22 11.8 18.3 2.3 1 1 1 2 2 2 0 Tho complex subunit 7 ZapD PF07072.11 EKX37203.1 - 6.5 6.5 14.0 0.25 11.0 3.9 2.4 1 1 2 3 3 3 0 Cell division protein DUF2203 PF09969.9 EKX37203.1 - 6.7 7.5 18.9 1.6e+02 3.0 13.1 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Rho_Binding PF08912.11 EKX37203.1 - 7.6 7.4 34.9 9 7.2 13.5 3.8 1 1 3 4 4 4 0 Rho Binding DLP_helical PF18709.1 EKX37203.1 - 8.4 5.5 21.7 5.2 6.2 10.5 2.6 1 1 1 2 2 2 0 Dynamin-like helical domain DUF4349 PF14257.6 EKX37203.1 - 8.6 5.7 15.1 73 2.7 14.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) TPR_12 PF13424.6 EKX37204.1 - 3.3e-22 78.6 7.0 4.6e-12 46.1 0.9 4.1 1 1 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 EKX37204.1 - 1.2e-10 40.8 3.7 0.0014 18.4 0.0 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 EKX37204.1 - 0.017 14.9 0.0 16 5.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EKX37204.1 - 0.029 14.5 4.3 20 5.6 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX37204.1 - 0.14 12.5 1.3 86 3.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat BRE1 PF08647.11 EKX37205.1 - 0.00017 21.6 15.3 0.09 12.9 1.9 3.3 1 1 2 3 3 3 2 BRE1 E3 ubiquitin ligase ATG16 PF08614.11 EKX37205.1 - 0.0044 17.3 14.9 0.0044 17.3 14.9 2.0 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) betaPIX_CC PF16523.5 EKX37205.1 - 0.015 15.1 16.7 0.12 12.2 0.7 3.2 1 1 2 3 3 3 0 betaPIX coiled coil P22_AR_C PF10548.9 EKX37205.1 - 0.049 13.8 0.1 0.22 11.7 0.0 2.0 2 0 0 2 2 2 0 P22AR C-terminal domain Uds1 PF15456.6 EKX37205.1 - 0.17 12.0 17.4 0.029 14.6 11.5 2.1 1 1 1 2 2 2 0 Up-regulated During Septation Synaptonemal_3 PF15191.6 EKX37205.1 - 0.19 11.5 3.8 0.16 11.7 1.5 2.1 1 1 1 2 2 2 0 Synaptonemal complex central element protein 3 DUF1664 PF07889.12 EKX37205.1 - 0.25 11.4 8.6 1.5 8.8 3.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 EKX37205.1 - 1.8 9.1 25.9 0.22 12.1 8.5 2.6 1 1 2 3 3 3 0 Apg6 coiled-coil region DUF910 PF06014.11 EKX37205.1 - 3.5 7.7 6.8 13 5.9 0.8 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF910) DUF4094 PF13334.6 EKX37205.1 - 4.4 7.8 9.3 14 6.2 6.6 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) V_ATPase_I PF01496.19 EKX37205.1 - 6.2 4.6 10.4 7.5 4.3 10.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.10 EKX37205.1 - 8.2 6.6 9.7 2.3 8.4 5.1 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family KIP1 PF07765.12 EKX37205.1 - 8.3 6.6 9.8 6.2 7.0 1.6 2.8 2 1 0 2 2 2 0 KIP1-like protein Jnk-SapK_ap_N PF09744.9 EKX37206.1 - 0.011 15.9 13.7 0.011 15.9 13.7 6.8 1 1 4 6 6 6 0 JNK_SAPK-associated protein-1 Gal4_dimer PF03902.13 EKX37206.1 - 0.16 12.2 7.0 0.86 9.8 0.8 3.3 3 0 0 3 3 3 0 Gal4-like dimerisation domain AAA_5 PF07728.14 EKX37206.1 - 0.83 9.6 4.4 0.27 11.2 0.3 2.3 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) HEAT_EZ PF13513.6 EKX37207.1 - 0.0017 18.8 0.0 0.01 16.3 0.0 2.4 1 0 0 1 1 1 1 HEAT-like repeat HEAT_2 PF13646.6 EKX37207.1 - 0.0023 18.3 0.7 0.017 15.5 0.1 2.9 3 0 0 3 3 3 1 HEAT repeats RHH_5 PF07878.11 EKX37207.1 - 0.012 15.4 0.8 0.063 13.2 0.1 2.6 2 0 0 2 2 2 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 HEAT PF02985.22 EKX37207.1 - 0.05 13.9 0.3 0.05 13.9 0.3 3.8 4 0 0 4 4 4 0 HEAT repeat DDE_Tnp_IS66 PF03050.14 EKX37207.1 - 0.16 11.4 0.2 0.3 10.5 0.2 1.4 1 0 0 1 1 1 0 Transposase IS66 family Viral_helicase1 PF01443.18 EKX37208.1 - 0.05 13.3 0.1 0.05 13.3 0.1 2.3 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PrmA PF06325.13 EKX37209.1 - 5.8e-11 42.3 0.0 8.6e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EKX37209.1 - 1.5e-06 27.9 0.1 0.0022 17.5 0.1 2.3 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_25 PF13649.6 EKX37209.1 - 0.00012 22.7 0.2 0.00028 21.5 0.2 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX37209.1 - 0.00021 21.1 0.7 0.00046 20.0 0.7 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EKX37209.1 - 0.00084 19.0 0.0 0.059 13.0 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 EKX37209.1 - 0.0024 17.7 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 EKX37209.1 - 0.0055 16.4 0.4 0.063 13.0 0.4 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.12 EKX37209.1 - 0.0071 17.1 0.0 0.014 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EKX37209.1 - 0.019 15.0 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PDZ_2 PF13180.6 EKX37210.1 - 6.8e-06 26.3 0.0 2.2e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX37210.1 - 0.00012 21.9 0.0 0.00027 20.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX37210.1 - 0.00074 19.8 0.1 0.0023 18.2 0.1 1.9 1 0 0 1 1 1 1 PDZ domain DUF1192 PF06698.11 EKX37210.1 - 0.014 15.5 3.3 1.6 8.8 0.2 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF1465 PF07323.12 EKX37210.1 - 0.015 15.1 3.2 0.015 15.1 3.2 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1465) ATG16 PF08614.11 EKX37210.1 - 0.16 12.2 37.0 0.65 10.2 9.8 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FapA PF03961.13 EKX37210.1 - 0.93 8.0 27.5 0.9 8.1 14.9 2.3 1 1 1 2 2 2 0 Flagellar Assembly Protein A Shugoshin_N PF07558.11 EKX37210.1 - 1.3 8.9 17.5 3 7.8 0.7 4.3 4 1 1 5 5 5 0 Shugoshin N-terminal coiled-coil region DUF4407 PF14362.6 EKX37210.1 - 2.6 7.3 32.0 2.6 7.3 19.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) bZIP_1 PF00170.21 EKX37210.1 - 3.2 7.9 28.1 0.35 11.0 3.4 3.8 2 1 1 3 3 3 0 bZIP transcription factor DivIC PF04977.15 EKX37210.1 - 3.7 7.4 26.0 0.041 13.6 1.8 4.3 2 2 1 3 3 3 0 Septum formation initiator T3SSipB PF16535.5 EKX37210.1 - 4.2 7.8 33.8 47 4.4 2.2 3.2 1 1 1 2 2 2 0 Type III cell invasion protein SipB PspB PF06667.12 EKX37210.1 - 6.1 7.0 8.0 11 6.1 0.3 3.1 3 0 0 3 3 3 0 Phage shock protein B UPF0449 PF15136.6 EKX37210.1 - 7.3 7.1 26.3 0.13 12.8 3.8 3.5 1 1 2 3 3 3 0 Uncharacterised protein family UPF0449 TMF_TATA_bd PF12325.8 EKX37210.1 - 8 6.7 30.0 0.18 12.0 10.8 3.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding N1221 PF07923.13 EKX37212.1 - 0.025 13.7 0.1 0.039 13.1 0.1 1.2 1 0 0 1 1 1 0 N1221-like protein PBP1_TM PF14812.6 EKX37212.1 - 2.7 8.4 5.6 1.2 9.5 2.6 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal XPG_I PF00867.18 EKX37213.1 - 2.7e-19 69.3 0.2 4.8e-19 68.5 0.2 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EKX37213.1 - 4.3e-17 62.5 0.0 7.7e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 EKX37213.1 - 0.002 17.7 0.1 0.0031 17.0 0.1 1.3 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 EKX37213.1 - 0.0025 18.4 0.0 0.0063 17.1 0.0 1.7 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold TPR_2 PF07719.17 EKX37213.1 - 0.12 12.5 1.3 0.98 9.7 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX37213.1 - 0.13 12.2 0.3 0.94 9.4 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_C1 PF00112.23 EKX37214.1 - 3.2e-51 174.5 4.8 4.2e-51 174.1 4.8 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EKX37214.1 - 0.0021 16.9 3.1 0.009 14.8 0.6 2.0 2 0 0 2 2 2 2 Peptidase C1-like family UBA PF00627.31 EKX37216.1 - 6.6e-05 22.7 0.4 0.00015 21.6 0.4 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Scramblase PF03803.15 EKX37216.1 - 0.00018 20.9 0.0 0.00045 19.6 0.0 1.6 1 1 0 1 1 1 1 Scramblase Yip1 PF04893.17 EKX37217.1 - 7.6e-11 42.0 15.1 9.9e-10 38.4 14.9 2.3 1 1 0 1 1 1 1 Yip1 domain Laminin_G_3 PF13385.6 EKX37218.1 - 2.5e-15 57.0 1.6 8.8e-13 48.7 0.2 2.6 1 1 1 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 EKX37218.1 - 0.0066 17.0 0.0 0.017 15.7 0.0 1.7 2 0 0 2 2 2 1 Laminin G domain LysM PF01476.20 EKX37218.1 - 0.012 15.6 0.0 0.16 12.0 0.0 2.6 2 0 0 2 2 2 0 LysM domain Pentaxin PF00354.17 EKX37218.1 - 0.054 13.2 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 Pentaxin family Herpes_BMRF2 PF04633.12 EKX37219.1 - 0.0034 16.7 1.5 0.0045 16.3 1.5 1.1 1 0 0 1 1 1 1 Herpesvirus BMRF2 protein FA_desaturase PF00487.24 EKX37219.1 - 0.0045 16.9 5.4 0.0048 16.8 5.4 1.0 1 0 0 1 1 1 1 Fatty acid desaturase DUF2721 PF11026.8 EKX37219.1 - 0.24 11.3 3.1 0.36 10.7 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) CLTH PF10607.9 EKX37220.1 - 0.0088 15.9 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain TetR_C_18 PF17923.1 EKX37220.1 - 0.12 12.9 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Cep57_CLD_2 PF14197.6 EKX37221.1 - 0.00016 21.7 1.7 0.00037 20.5 1.7 1.7 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 Rootletin PF15035.6 EKX37221.1 - 0.021 14.8 0.9 0.79 9.7 0.1 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Csm1_N PF18504.1 EKX37221.1 - 0.025 14.9 1.1 0.049 14.0 0.3 2.0 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF4686 PF15742.5 EKX37221.1 - 0.069 12.3 2.3 1.7 7.7 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4686) HEAT_PBS PF03130.16 EKX37221.1 - 0.31 11.8 1.5 2 9.3 0.1 2.4 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat Ribosomal_S27e PF01667.17 EKX37222.1 - 6.2e-28 96.3 5.2 7.6e-28 96.0 5.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 Mu-like_Com PF10122.9 EKX37222.1 - 0.089 12.3 2.2 5.2 6.6 0.4 2.2 1 1 1 2 2 2 0 Mu-like prophage protein Com Hamartin PF04388.12 EKX37224.1 - 0.26 9.9 8.7 0.28 9.8 8.7 1.1 1 0 0 1 1 1 0 Hamartin protein Acetyltransf_1 PF00583.25 EKX37225.1 - 1.2e-16 60.9 0.0 1.5e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EKX37225.1 - 4.1e-10 39.7 0.0 5.5e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EKX37225.1 - 5.6e-09 36.3 0.1 7.4e-09 35.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EKX37225.1 - 0.0076 16.4 0.1 0.016 15.3 0.1 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Neuralized PF07177.12 EKX37226.1 - 8.4e-06 25.9 0.0 8.7e-06 25.8 0.0 1.0 1 0 0 1 1 1 1 Neuralized SPRY PF00622.28 EKX37226.1 - 0.034 14.2 0.0 0.038 14.1 0.0 1.0 1 0 0 1 1 1 0 SPRY domain RRM_1 PF00076.22 EKX37227.1 - 1.2e-08 34.7 0.0 2.5e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LysM PF01476.20 EKX37229.1 - 1.8e-06 27.9 0.0 2e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 LysM domain NYN_YacP PF05991.11 EKX37232.1 - 3.7e-33 114.8 0.0 6.3e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 YacP-like NYN domain zf-UBR PF02207.20 EKX37233.1 - 3.5e-19 68.7 12.2 9.7e-19 67.3 12.2 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) zf-RING_5 PF14634.6 EKX37233.1 - 0.023 14.7 0.4 0.023 14.7 0.4 3.0 3 0 0 3 3 3 0 zinc-RING finger domain zf-B_box PF00643.24 EKX37233.1 - 1.2 9.4 7.8 0.31 11.2 3.5 2.4 2 0 0 2 2 2 0 B-box zinc finger MSC PF09402.10 EKX37234.1 - 0.015 14.8 0.5 0.03 13.8 0.3 1.4 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain PH PF00169.29 EKX37234.1 - 0.092 13.3 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 PH domain Thioredoxin_6 PF13848.6 EKX37235.1 - 0.002 18.1 0.0 0.16 11.9 0.0 2.7 2 1 0 2 2 2 1 Thioredoxin-like domain DUF4407 PF14362.6 EKX37235.1 - 0.0043 16.4 22.6 0.0059 16.0 9.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) DUF3584 PF12128.8 EKX37235.1 - 0.0045 14.6 31.4 0.0078 13.8 16.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3584) OAF PF14941.6 EKX37235.1 - 0.036 13.5 3.6 0.077 12.4 3.6 1.6 1 0 0 1 1 1 0 Transcriptional regulator, Out at first Golgin_A5 PF09787.9 EKX37235.1 - 5.8 6.3 51.7 0.37 10.2 8.7 3.3 4 0 0 4 4 4 0 Golgin subfamily A member 5 DUF948 PF06103.11 EKX37235.1 - 8.9 6.6 12.4 9.8 6.5 2.0 3.5 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Sulfotransfer_4 PF17784.1 EKX37235.1 - 9.1 6.0 8.2 4.2 7.2 3.0 2.7 2 1 1 4 4 4 0 Sulfotransferase domain PH PF00169.29 EKX37236.1 - 0.1 13.1 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 PH domain PH PF00169.29 EKX37237.1 - 0.084 13.4 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 PH domain K_channel_TID PF07941.11 EKX37238.1 - 3.9 8.0 6.9 0.39 11.2 0.5 2.3 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain DnaJ_C PF01556.18 EKX37239.1 - 1.4e-26 93.4 0.0 1.8e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EKX37239.1 - 3.3e-26 91.2 1.9 5e-26 90.6 1.9 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EKX37239.1 - 2.5e-11 43.7 10.3 3.8e-11 43.2 10.3 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EKX37239.1 - 5.9e-06 26.2 8.5 0.023 14.7 0.4 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein A2L_zn_ribbon PF08792.10 EKX37239.1 - 0.0055 16.4 7.7 0.15 11.9 0.4 3.2 2 1 1 3 3 3 1 A2L zinc ribbon domain DUF3152 PF11350.8 EKX37239.1 - 0.021 14.6 0.2 0.037 13.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) HypA PF01155.19 EKX37239.1 - 0.033 14.2 3.6 3.4 7.7 0.3 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 EKX37239.1 - 0.059 13.0 1.8 1.6 8.3 0.2 2.2 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 Lar_restr_allev PF14354.6 EKX37239.1 - 0.068 13.6 10.4 2.3 8.6 0.1 2.9 1 1 2 3 3 3 0 Restriction alleviation protein Lar MFS_5 PF05631.14 EKX37240.1 - 3.1e-70 236.8 6.7 3.1e-70 236.8 6.7 1.7 1 1 1 2 2 2 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 EKX37240.1 - 1.8e-16 60.0 28.4 1.4e-15 57.1 29.2 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Cyclin_N PF00134.23 EKX37241.1 - 9.3e-27 93.3 0.7 4.7e-26 91.0 0.8 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EKX37241.1 - 2.2e-05 24.5 0.0 4.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain TFIIB PF00382.19 EKX37241.1 - 0.0016 18.4 0.2 0.45 10.6 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat cobW PF02492.19 EKX37242.1 - 1.1e-52 178.2 0.0 1.6e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EKX37242.1 - 1.1e-18 66.9 0.0 2e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 EKX37242.1 - 2.7e-05 24.1 0.6 0.21 11.5 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EKX37242.1 - 0.0006 20.2 0.1 0.0044 17.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 EKX37242.1 - 0.021 14.9 0.1 3.2 7.9 0.1 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase MobB PF03205.14 EKX37242.1 - 0.042 13.7 0.1 0.34 10.8 0.1 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 EKX37242.1 - 0.047 13.7 0.1 0.094 12.7 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EKX37242.1 - 0.051 13.8 0.6 0.17 12.2 0.2 2.1 2 1 1 3 3 3 0 AAA domain T2SSE PF00437.20 EKX37242.1 - 0.095 11.7 0.3 0.34 9.9 0.1 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein SRPRB PF09439.10 EKX37242.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EKX37242.1 - 0.12 11.9 0.1 9.1 5.8 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 EKX37242.1 - 0.12 12.5 0.1 0.24 11.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EKX37242.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 EKX37242.1 - 0.18 11.0 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 EKX37242.1 - 0.29 10.9 1.0 0.56 10.0 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Ribosomal_S9 PF00380.19 EKX37243.1 - 4.6e-39 133.7 2.0 6.4e-39 133.2 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S9/S16 RMF PF04957.12 EKX37244.1 - 0.034 14.4 0.4 2.2 8.6 0.1 2.4 2 0 0 2 2 2 0 Ribosome modulation factor EF-hand_1 PF00036.32 EKX37245.1 - 4.2e-10 38.4 0.5 6.2e-05 22.3 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX37245.1 - 6.8e-09 35.0 0.5 0.00051 19.8 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EKX37245.1 - 2.3e-07 30.0 0.3 0.00024 20.5 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX37245.1 - 3.4e-05 24.2 1.8 0.0026 18.2 0.1 2.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 EKX37245.1 - 0.0025 17.6 0.6 1.3 8.9 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair Mpt_N PF09176.11 EKX37245.1 - 0.11 12.7 0.1 8.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal AI-2E_transport PF01594.16 EKX37246.1 - 5.2e-43 147.4 32.8 1.5e-42 146.0 22.4 2.4 1 1 1 2 2 2 2 AI-2E family transporter Trp_oprn_chp PF09534.10 EKX37246.1 - 0.65 9.8 5.0 1.2 8.9 5.0 1.4 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) NS3_envE PF02723.14 EKX37246.1 - 7.9 6.6 11.0 11 6.2 1.3 2.8 2 0 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E ADPrib_exo_Tox PF03496.14 EKX37247.1 - 1.2e-05 24.7 0.0 2.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosyltransferase exoenzyme ART PF01129.18 EKX37247.1 - 0.00029 20.2 0.0 0.00075 18.8 0.0 1.7 1 1 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase EF-hand_7 PF13499.6 EKX37247.1 - 0.0035 17.7 1.3 0.013 15.9 1.3 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EKX37247.1 - 0.011 15.6 0.1 0.043 13.7 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 EKX37247.1 - 0.06 13.3 0.2 0.21 11.6 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain TPX2 PF06886.11 EKX37247.1 - 5.5 7.3 9.7 3 8.1 2.5 3.1 3 0 0 3 3 3 0 Targeting protein for Xklp2 (TPX2) Not1 PF04054.15 EKX37248.1 - 4.4e-140 466.8 0.5 4.4e-140 466.8 0.5 1.8 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 EKX37248.1 - 4.2e-83 278.2 3.9 1.2e-82 276.7 3.9 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 EKX37248.1 - 1.6e-71 239.4 0.6 4.6e-71 237.9 0.6 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 EKX37248.1 - 2.1e-51 173.7 8.1 4.5e-51 172.6 6.7 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) Ribosomal_L27A PF00828.19 EKX37248.1 - 0.12 13.0 0.1 4.8 7.9 0.0 3.2 3 0 0 3 3 3 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A COQ9 PF08511.11 EKX37249.1 - 5.5e-19 67.7 0.0 8.1e-19 67.2 0.0 1.3 1 0 0 1 1 1 1 COQ9 Baculo_19 PF04798.12 EKX37249.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Baculovirus 19 kDa protein conserved region EbsA PF17255.2 EKX37251.1 - 5 7.5 6.0 6.6 7.1 0.7 2.2 2 0 0 2 2 2 0 EbsA-like protein Sec1 PF00995.23 EKX37252.1 - 4.4e-46 158.3 0.0 2.6e-24 86.4 0.0 2.0 2 0 0 2 2 2 2 Sec1 family CENP-B_dimeris PF09026.10 EKX37252.1 - 0.16 12.3 6.2 0.57 10.6 4.8 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RtcB PF01139.17 EKX37253.1 - 3.5e-138 461.3 1.6 4.5e-138 460.9 1.6 1.1 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB ubiquitin PF00240.23 EKX37254.1 - 4.5e-47 157.7 1.1 1.7e-33 114.2 0.5 2.1 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 EKX37254.1 - 1.1e-23 82.9 1.3 6.5e-16 57.9 0.4 2.1 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EKX37254.1 - 1.7e-06 28.3 0.2 0.00018 21.9 0.1 2.9 2 2 0 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EKX37254.1 - 0.0016 18.3 0.0 0.015 15.2 0.1 2.1 2 0 0 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EKX37254.1 - 0.0027 17.8 0.1 0.074 13.2 0.1 2.7 2 2 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EKX37254.1 - 0.0049 17.2 0.1 0.016 15.6 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 EKX37254.1 - 0.037 14.1 3.5 12 6.0 0.1 3.6 3 1 1 4 4 4 0 Ubiquitin-like domain DUF2407 PF10302.9 EKX37254.1 - 0.057 14.0 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EKX37254.1 - 0.14 12.0 0.1 0.58 10.0 0.0 2.0 2 1 0 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain TUG-UBL1 PF11470.8 EKX37254.1 - 0.15 12.3 0.0 3.9 7.8 0.0 2.2 2 0 0 2 2 2 0 TUG ubiquitin-like domain DUF4200 PF13863.6 EKX37255.1 - 1.4e-29 102.9 43.8 2.3e-28 99.0 31.3 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF4200) bZIP_1 PF00170.21 EKX37255.1 - 0.21 11.7 0.2 0.21 11.7 0.2 4.0 2 1 1 3 3 3 0 bZIP transcription factor Spc7 PF08317.11 EKX37255.1 - 0.71 8.7 36.0 0.12 11.2 2.2 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Mago_nashi PF02792.14 EKX37255.1 - 0.75 9.9 6.3 7.4 6.7 3.6 2.4 2 0 0 2 2 2 0 Mago nashi protein DASH_Dam1 PF08653.10 EKX37255.1 - 2.5 8.0 9.6 3.3 7.6 1.9 3.8 3 1 1 4 4 4 0 DASH complex subunit Dam1 MFS_1 PF07690.16 EKX37257.1 - 5.4e-10 38.7 21.5 8.3e-10 38.1 21.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Helicase_C PF00271.31 EKX37259.1 - 1.4e-17 64.0 0.0 3.5e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EKX37259.1 - 1.4e-16 60.8 0.0 6.6e-13 48.8 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 EKX37259.1 - 3.4e-06 27.2 0.0 0.0001 22.4 0.0 3.0 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit CLTH PF10607.9 EKX37260.1 - 7.9e-06 25.8 1.6 5.8e-05 23.0 0.1 2.7 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain Collagen PF01391.18 EKX37261.1 - 2.2e-28 97.8 98.7 1e-08 34.8 28.9 3.4 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) UDG PF03167.19 EKX37262.1 - 3.7e-07 30.3 0.0 7.7e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily 5_nucleotid_C PF02872.18 EKX37263.1 - 5.4e-18 65.7 0.0 4.6e-09 36.7 0.0 2.4 2 0 0 2 2 2 2 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EKX37263.1 - 1.3e-15 58.5 0.0 2.3e-06 28.3 0.0 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase EF-hand_7 PF13499.6 EKX37263.1 - 2.1e-13 50.5 1.7 2.2e-06 28.0 0.2 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX37263.1 - 2.4e-12 45.4 7.6 0.00062 19.1 0.3 4.5 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 EKX37263.1 - 1.1e-10 40.5 7.5 0.00053 19.4 0.2 3.8 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EKX37263.1 - 2.6e-08 33.6 0.9 0.00071 19.4 0.1 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX37263.1 - 2.6e-08 33.1 3.0 0.097 12.7 0.1 4.1 4 0 0 4 4 4 3 EF-hand domain Cbl_N2 PF02761.14 EKX37263.1 - 0.021 15.6 0.4 11 6.8 0.1 2.8 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, EF hand-like domain NusG PF02357.19 EKX37263.1 - 0.035 14.6 0.0 22 5.6 0.0 2.8 2 0 0 2 2 2 0 Transcription termination factor nusG SPARC_Ca_bdg PF10591.9 EKX37263.1 - 0.042 14.2 0.3 1.1 9.6 0.2 2.7 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Ead_Ea22 PF13935.6 EKX37263.1 - 0.15 12.7 0.7 0.4 11.3 0.7 1.7 1 0 0 1 1 1 0 Ead/Ea22-like protein EF-hand_4 PF12763.7 EKX37263.1 - 0.65 10.0 5.0 0.26 11.2 0.5 2.7 3 0 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand MttA_Hcf106 PF02416.16 EKX37265.1 - 9.7e-09 34.4 2.7 1.8e-08 33.6 2.6 1.5 1 1 0 1 1 1 1 mttA/Hcf106 family YtxH PF12732.7 EKX37265.1 - 0.008 16.7 0.4 0.012 16.1 0.4 1.3 1 0 0 1 1 1 1 YtxH-like protein Spore_III_AB PF09548.10 EKX37265.1 - 0.24 11.5 2.5 7.7 6.6 0.7 2.1 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) EF-hand_1 PF00036.32 EKX37266.1 - 5.6e-07 28.7 0.7 9.6e-07 27.9 0.0 1.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EKX37266.1 - 6.3e-06 25.7 0.2 1.8e-05 24.3 0.1 1.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 EKX37266.1 - 2.6e-05 24.6 0.3 3.3e-05 24.2 0.3 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EKX37266.1 - 9.6e-05 22.1 2.4 0.027 14.3 0.1 1.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 EKX37266.1 - 0.0035 17.3 0.1 0.0037 17.2 0.1 1.1 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 EKX37266.1 - 0.0037 16.7 1.2 0.0038 16.7 0.1 1.6 2 0 0 2 2 2 1 EF hand EF-hand_14 PF17959.1 EKX37266.1 - 0.089 13.1 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain Dockerin_1 PF00404.18 EKX37266.1 - 0.1 12.8 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Dockerin type I domain AAA_22 PF13401.6 EKX37268.1 - 0.0073 16.6 0.0 0.041 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain MutS_III PF05192.18 EKX37268.1 - 0.021 15.1 0.0 0.038 14.2 0.0 1.7 1 1 0 1 1 1 0 MutS domain III DpnI_C PF17726.1 EKX37268.1 - 0.025 14.7 5.7 0.17 12.0 2.9 2.6 2 0 0 2 2 2 0 Dam-replacing HTH domain LMBR1 PF04791.16 EKX37268.1 - 0.037 13.0 5.3 0.052 12.5 5.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein AAA_25 PF13481.6 EKX37268.1 - 0.037 13.6 0.0 0.1 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EKX37268.1 - 0.062 13.1 0.0 0.062 13.1 0.0 3.1 3 1 0 3 3 3 0 AAA domain AAA_13 PF13166.6 EKX37268.1 - 0.11 11.1 26.6 0.019 13.7 22.7 1.6 2 0 0 2 2 2 0 AAA domain Sec34 PF04136.15 EKX37268.1 - 2.5 8.0 12.1 0.078 12.8 2.7 2.4 1 1 1 2 2 2 0 Sec34-like family Jnk-SapK_ap_N PF09744.9 EKX37268.1 - 3.1 8.0 42.2 0.046 14.0 13.1 2.9 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 WD40 PF00400.32 EKX37269.1 - 0.0026 18.6 0.5 0.0063 17.3 0.1 1.9 2 0 0 2 2 2 1 WD domain, G-beta repeat EF-hand_7 PF13499.6 EKX37270.1 - 6.6e-23 81.0 11.2 4.6e-10 39.8 1.3 3.8 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 EKX37270.1 - 4.6e-19 66.7 18.3 7.2e-07 28.6 0.2 6.3 6 1 0 6 6 6 4 EF-hand domain EF-hand_1 PF00036.32 EKX37270.1 - 9.2e-17 59.3 32.8 8.2e-07 28.1 0.6 7.1 7 1 0 7 7 7 4 EF hand EF-hand_8 PF13833.6 EKX37270.1 - 1.1e-16 60.4 21.2 7.6e-08 32.1 2.1 6.6 3 2 3 6 6 6 4 EF-hand domain pair EF-hand_5 PF13202.6 EKX37270.1 - 2e-07 30.2 22.4 4.4e-05 22.8 0.2 5.6 6 0 0 6 6 6 3 EF hand EF-hand_9 PF14658.6 EKX37270.1 - 2e-06 28.0 0.1 0.0044 17.3 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_11 PF08976.11 EKX37270.1 - 0.00023 22.0 0.1 0.3 12.0 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EKX37270.1 - 0.0021 18.0 6.9 0.003 17.5 0.6 3.0 3 1 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EKX37270.1 - 0.0059 16.9 7.7 0.15 12.4 0.2 3.2 2 1 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 EKX37270.1 - 0.0096 15.9 0.3 0.0096 15.9 0.3 3.0 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0154) EF-hand_14 PF17959.1 EKX37270.1 - 0.089 13.1 7.2 14 6.1 0.7 3.6 3 1 1 4 4 4 0 EF-hand domain DUF3752 PF12572.8 EKX37271.1 - 3.5e-17 63.3 14.1 3.5e-17 63.3 14.1 3.2 1 1 2 3 3 3 1 Protein of unknown function (DUF3752) DHR10 PF18595.1 EKX37272.1 - 0.021 14.9 15.9 0.021 14.9 15.9 3.6 3 1 0 3 3 3 0 Designed helical repeat protein 10 domain TFIIA PF03153.13 EKX37272.1 - 0.049 13.6 29.2 0.075 13.0 29.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TolA_bind_tri PF16331.5 EKX37272.1 - 0.47 10.6 22.0 0.23 11.6 5.2 3.4 2 1 1 3 3 3 0 TolA binding protein trimerisation FUSC PF04632.12 EKX37272.1 - 1.2 7.6 5.1 2 6.8 5.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF948 PF06103.11 EKX37272.1 - 1.5 9.2 5.2 7.8 6.8 0.9 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Sec8_exocyst PF04048.14 EKX37272.1 - 1.5 8.7 11.4 0.14 12.1 4.0 2.5 2 1 1 3 3 3 0 Sec8 exocyst complex component specific domain DUF4349 PF14257.6 EKX37272.1 - 2.4 7.5 10.7 1.4 8.3 7.2 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4349) APC_N_CC PF16689.5 EKX37272.1 - 4 7.6 13.8 8 6.6 6.6 3.1 2 1 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Fez1 PF06818.15 EKX37272.1 - 4.2 7.8 38.3 0.19 12.1 28.4 2.3 1 1 0 2 2 2 0 Fez1 DUF1664 PF07889.12 EKX37272.1 - 5.5 7.0 12.1 0.36 10.9 1.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF745 PF05335.13 EKX37272.1 - 5.7 6.6 21.3 0.094 12.4 8.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF745) DUF3450 PF11932.8 EKX37272.1 - 6.2 6.0 28.5 0.19 11.0 1.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) FlaC_arch PF05377.11 EKX37272.1 - 7.9 7.0 16.1 5.6 7.4 5.8 3.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) RNase_P_Rpp14 PF01900.19 EKX37273.1 - 1.3e-09 38.2 0.0 1.9e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Calreticulin PF00262.18 EKX37274.1 - 4.5e-143 476.5 14.8 7.6e-143 475.8 14.8 1.3 1 0 0 1 1 1 1 Calreticulin family FAM176 PF14851.6 EKX37274.1 - 0.0059 16.3 1.3 0.0073 16.0 0.0 1.7 2 0 0 2 2 2 1 FAM176 family DUF5576 PF17739.1 EKX37274.1 - 0.17 12.0 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5576) OAD_gamma PF04277.13 EKX37274.1 - 0.24 12.0 2.3 0.62 10.7 0.1 2.8 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain IDO PF01231.18 EKX37275.1 - 0.005 15.7 0.1 0.0054 15.6 0.1 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Filamin PF00630.19 EKX37277.1 - 3.4e-25 88.8 0.0 1.8e-11 44.7 0.0 2.0 1 1 1 2 2 2 2 Filamin/ABP280 repeat Invasin_D3 PF09134.10 EKX37277.1 - 4.2e-07 30.2 2.8 0.017 15.4 0.2 2.2 2 0 0 2 2 2 2 Invasin, domain 3 Cadherin_5 PF17892.1 EKX37277.1 - 2.6e-05 24.1 0.1 0.059 13.3 0.0 2.2 2 0 0 2 2 2 2 Cadherin-like domain DUF5011 PF16403.5 EKX37277.1 - 0.00088 19.3 1.3 0.2 11.8 0.3 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF5011) Big_1 PF02369.16 EKX37277.1 - 0.0093 16.0 0.4 2.7 8.0 0.0 3.0 2 1 0 2 2 2 1 Bacterial Ig-like domain (group 1) YtkA PF13115.6 EKX37277.1 - 0.012 16.2 0.0 3.9 8.1 0.0 2.3 2 0 0 2 2 2 0 YtkA-like Big_3_5 PF16640.5 EKX37277.1 - 0.49 10.6 3.5 18 5.6 0.1 2.4 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) Ion_trans PF00520.31 EKX37280.1 - 2.2e-05 23.8 0.0 2.3e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Ion transport protein RNase_T PF00929.24 EKX37281.1 - 1.8e-10 41.6 0.0 2e-10 41.5 0.0 1.0 1 0 0 1 1 1 1 Exonuclease Guanylate_cyc PF00211.20 EKX37282.1 - 9.5e-23 80.8 0.1 1.3e-22 80.4 0.1 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DXP_reductoisom PF02670.16 EKX37283.1 - 8.5e-47 159.1 0.3 1.4e-46 158.4 0.3 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXPR_C PF13288.6 EKX37283.1 - 6.6e-38 129.5 0.0 1.1e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain DXP_redisom_C PF08436.12 EKX37283.1 - 2.1e-33 114.3 0.0 5.1e-33 113.1 0.0 1.7 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain MttA_Hcf106 PF02416.16 EKX37283.1 - 0.023 14.0 0.1 0.072 12.4 0.1 1.8 1 0 0 1 1 1 0 mttA/Hcf106 family Guanylate_cyc PF00211.20 EKX37285.1 - 9.5e-23 80.8 0.1 1.3e-22 80.4 0.1 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain GCP_C_terminal PF04130.13 EKX37286.1 - 1.4e-48 165.9 3.9 1.4e-48 165.9 3.9 2.7 4 0 0 4 4 4 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EKX37286.1 - 4.6e-28 98.7 0.4 2.9e-27 96.1 0.2 2.5 2 1 0 2 2 2 1 Gamma tubulin complex component N-terminal DUF5300 PF17224.3 EKX37286.1 - 0.023 15.0 0.7 0.065 13.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5300) ADPrib_exo_Tox PF03496.14 EKX37287.1 - 4.8e-05 22.8 0.0 4.8e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosyltransferase exoenzyme ART PF01129.18 EKX37287.1 - 0.00014 21.2 0.0 0.00018 20.9 0.0 1.1 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase RbpA PF13397.6 EKX37287.1 - 0.14 12.8 0.0 0.16 12.6 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase-binding protein MMR_HSR1 PF01926.23 EKX37288.1 - 1.2e-22 80.1 0.0 3.4e-22 78.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.22 EKX37288.1 - 2.8e-21 75.7 4.5 4.4e-14 52.3 0.2 2.7 2 1 0 2 2 2 2 GTP1/OBG FeoB_N PF02421.18 EKX37288.1 - 2.1e-07 30.6 0.0 7.1e-07 28.9 0.0 1.9 2 1 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 EKX37288.1 - 0.00036 20.0 0.0 0.00091 18.7 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family MeaB PF03308.16 EKX37288.1 - 0.0024 16.9 0.0 1.2 8.1 0.0 2.7 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Ras PF00071.22 EKX37288.1 - 0.093 12.3 0.0 0.38 10.3 0.0 2.1 1 1 0 1 1 1 0 Ras family CDC45 PF02724.14 EKX37288.1 - 0.38 9.0 16.6 0.52 8.5 16.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 EKX37288.1 - 0.49 9.7 19.0 0.84 9.0 19.0 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.12 EKX37288.1 - 1.1 7.4 20.6 1.6 6.9 20.6 1.1 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 EKX37288.1 - 1.4 8.7 11.4 2.6 7.8 11.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RRN3 PF05327.11 EKX37288.1 - 2.3 6.6 9.8 3.8 5.9 9.8 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Dynamin_N PF00350.23 EKX37288.1 - 2.9 7.9 9.3 11 6.1 0.1 3.3 2 2 1 3 3 2 0 Dynamin family PBP_sp32 PF07222.12 EKX37288.1 - 4.6 6.6 9.8 9.4 5.6 9.8 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 PI3_PI4_kinase PF00454.27 EKX37289.1 - 0.002 18.0 0.0 0.0024 17.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Ank_2 PF12796.7 EKX37290.1 - 3.8e-47 158.8 0.0 5.5e-08 33.3 0.0 4.6 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX37290.1 - 8e-45 150.7 0.2 7.9e-05 23.1 0.0 8.0 8 0 0 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX37290.1 - 3.8e-30 103.6 3.2 0.0019 18.5 0.1 8.1 7 1 1 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX37290.1 - 2.4e-18 64.3 0.1 1.7 9.5 0.0 8.1 9 0 0 9 9 9 5 Ankyrin repeat Chol_subst-bind PF09129.11 EKX37290.1 - 8.1e-11 41.4 0.0 2.6 6.9 0.0 6.2 2 2 4 6 6 6 5 Cholesterol oxidase, substrate-binding Ank PF00023.30 EKX37290.1 - 5.4e-10 39.3 0.9 6 7.5 0.0 8.0 9 0 0 9 9 9 2 Ankyrin repeat RHH_5 PF07878.11 EKX37290.1 - 8.1e-07 28.8 0.3 22 5.0 0.0 6.0 6 0 0 6 6 6 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 MerR-DNA-bind PF09278.11 EKX37290.1 - 4.2e-05 24.0 9.4 38 4.9 0.0 6.9 7 0 0 7 7 7 0 MerR, DNA binding VWA_3_C PF18571.1 EKX37290.1 - 2.6 8.0 5.2 62 3.6 0.0 4.8 7 0 0 7 7 7 0 von Willebrand factor type A C-terminal domain ART PF01129.18 EKX37291.1 - 3.9e-07 29.6 0.0 4.5e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase ADPrib_exo_Tox PF03496.14 EKX37291.1 - 7.8e-06 25.4 0.0 1e-05 25.0 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosyltransferase exoenzyme PI3Ka PF00613.20 EKX37292.1 - 7.8e-36 123.2 0.6 1.4e-35 122.4 0.6 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EKX37292.1 - 1.2e-31 110.5 0.4 1.1e-15 58.1 0.2 3.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 EKX37292.1 - 1.2e-19 70.6 0.0 2.5e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 T2SSF PF00482.23 EKX37292.1 - 0.031 14.2 0.7 0.31 11.0 0.1 2.5 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F FlgM PF04316.13 EKX37292.1 - 0.048 14.0 0.1 0.15 12.5 0.1 1.8 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM DUF4253 PF14062.6 EKX37292.1 - 0.1 12.8 0.5 0.75 10.0 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4253) DUF4596 PF15363.6 EKX37293.1 - 0.043 14.1 0.3 0.15 12.3 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) Glyco_transf_41 PF13844.6 EKX37293.1 - 0.076 11.4 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 41 Dynamin_N PF00350.23 EKX37294.1 - 0.00017 21.7 3.1 0.00023 21.3 0.0 2.5 2 1 0 2 2 2 1 Dynamin family Toprim_4 PF13662.6 EKX37294.1 - 0.00055 20.3 0.1 0.5 10.9 0.0 2.9 3 0 0 3 3 3 2 Toprim domain Nitr_red_assoc PF09655.10 EKX37294.1 - 0.00057 20.6 1.3 0.42 11.2 0.7 2.5 2 0 0 2 2 2 2 Conserved nitrate reductase-associated protein (Nitr_red_assoc) MMR_HSR1 PF01926.23 EKX37294.1 - 0.0081 16.2 0.1 0.03 14.4 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 EKX37294.1 - 0.0099 15.2 2.5 1.6 8.0 0.1 2.5 3 0 0 3 3 3 2 AIG1 family AAA_5 PF07728.14 EKX37294.1 - 0.077 13.0 0.3 0.19 11.7 0.3 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2894 PF11445.8 EKX37294.1 - 0.39 11.2 7.9 0.22 12.0 5.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) Exonuc_VII_L PF02601.15 EKX37294.1 - 0.44 10.1 5.9 0.68 9.4 5.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Aida_N PF08910.10 EKX37294.1 - 0.79 10.1 4.8 0.51 10.7 1.1 2.4 1 1 2 3 3 3 0 Aida N-terminus PI3_PI4_kinase PF00454.27 EKX37295.1 - 7e-16 58.8 0.0 6.4e-11 42.5 0.0 2.0 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase Ank_4 PF13637.6 EKX37296.1 - 1.6e-98 321.9 14.9 2.7e-11 43.8 0.1 18.7 18 1 0 18 18 18 18 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX37296.1 - 9.6e-80 263.3 7.6 1.1e-07 32.4 0.0 12.0 1 1 13 14 14 14 14 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX37296.1 - 4.5e-38 124.9 2.1 0.003 17.9 0.0 17.8 20 0 0 20 20 20 9 Ankyrin repeat Ank_5 PF13857.6 EKX37296.1 - 3.4e-27 94.1 19.6 0.00022 21.5 0.1 15.2 10 7 9 19 19 19 10 Ankyrin repeats (many copies) Ank PF00023.30 EKX37296.1 - 1.3e-19 69.7 16.3 2.2e-06 27.8 0.0 13.9 16 0 0 16 16 16 3 Ankyrin repeat Chol_subst-bind PF09129.11 EKX37296.1 - 1.1e-15 57.4 0.0 3.6 6.4 0.0 13.1 4 4 12 16 16 16 2 Cholesterol oxidase, substrate-binding MerR-DNA-bind PF09278.11 EKX37296.1 - 0.0037 17.8 34.9 23 5.6 0.0 12.4 15 0 0 15 15 15 0 MerR, DNA binding GlnE PF03710.15 EKX37296.1 - 1 8.7 13.0 8.2 5.8 0.0 6.3 6 2 1 8 8 8 0 Glutamate-ammonia ligase adenylyltransferase ART PF01129.18 EKX37297.1 - 1.5e-07 30.9 0.0 1.8e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase ADPrib_exo_Tox PF03496.14 EKX37297.1 - 5.9e-06 25.8 0.0 7.5e-06 25.4 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosyltransferase exoenzyme PI3_PI4_kinase PF00454.27 EKX37298.1 - 7e-16 58.8 0.0 6.4e-11 42.5 0.0 2.0 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase Peptidase_C14 PF00656.22 EKX37300.1 - 1.2e-08 35.2 0.0 2.1e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Caspase domain DUF4596 PF15363.6 EKX37300.1 - 0.15 12.4 0.3 0.33 11.2 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) Glyco_transf_41 PF13844.6 EKX37300.1 - 0.2 10.0 0.0 0.29 9.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 41 Raptor_N PF14538.6 EKX37300.1 - 0.23 11.4 0.0 0.97 9.4 0.0 1.9 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain Ank_2 PF12796.7 EKX37301.1 - 4.8e-62 206.5 2.0 4.9e-08 33.5 0.0 5.2 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX37301.1 - 1.2e-46 156.5 0.9 5.9e-07 29.9 0.0 8.7 7 1 2 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX37301.1 - 2e-27 94.9 12.1 0.04 14.3 0.0 9.1 3 2 6 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX37301.1 - 8.8e-23 77.9 2.6 0.75 10.6 0.0 9.6 10 0 0 10 10 10 7 Ankyrin repeat Chol_subst-bind PF09129.11 EKX37301.1 - 3.1e-13 49.4 0.0 2 7.3 0.0 7.5 1 1 7 8 8 8 5 Cholesterol oxidase, substrate-binding Ank PF00023.30 EKX37301.1 - 9.1e-13 48.0 4.1 12 6.6 0.0 9.6 10 0 0 10 10 10 1 Ankyrin repeat RHH_5 PF07878.11 EKX37301.1 - 1.2e-12 47.5 0.9 1.6 8.7 0.1 7.9 9 0 0 9 9 9 4 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 zf-CCCH_6 PF18585.1 EKX37301.1 - 9.5e-07 28.6 0.1 77 3.3 0.0 8.3 9 0 0 9 9 9 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 eIF3_p135 PF12807.7 EKX37301.1 - 0.0077 16.3 0.0 1.4 8.9 0.0 3.1 3 1 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 VWA_3_C PF18571.1 EKX37301.1 - 0.016 15.0 3.6 66 3.5 0.0 5.1 5 0 0 5 5 5 0 von Willebrand factor type A C-terminal domain Met_asp_mut_E PF06368.11 EKX37301.1 - 0.023 13.2 0.0 8.4 4.7 0.0 3.5 2 1 1 4 4 4 0 Methylaspartate mutase E chain (MutE) AP_endonuc_2_N PF07582.12 EKX37301.1 - 0.039 13.7 6.4 56 3.6 0.0 5.3 7 0 0 7 7 7 0 AP endonuclease family 2 C terminus Peptidase_M7 PF02031.16 EKX37301.1 - 0.7 10.0 5.2 22 5.2 0.1 4.2 1 1 3 5 5 5 0 Streptomyces extracellular neutral proteinase (M7) family ART PF01129.18 EKX37302.1 - 4.4e-07 29.4 0.0 5e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase ADPrib_exo_Tox PF03496.14 EKX37302.1 - 8.3e-06 25.3 0.0 1.1e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosyltransferase exoenzyme PI3_PI4_kinase PF00454.27 EKX37303.1 - 1e-35 123.8 0.0 9.1e-22 78.1 0.0 2.6 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EKX37303.1 - 6.3e-35 120.3 0.5 1.1e-34 119.5 0.5 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) T2SSF PF00482.23 EKX37303.1 - 0.011 15.6 0.8 0.16 11.9 0.2 2.5 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Flu_M1_C PF08289.11 EKX37303.1 - 0.02 15.1 0.2 23 5.3 0.0 3.3 3 0 0 3 3 3 0 Influenza Matrix protein (M1) C-terminal domain FlgM PF04316.13 EKX37303.1 - 0.029 14.7 0.1 0.082 13.3 0.1 1.7 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM DUF4253 PF14062.6 EKX37303.1 - 0.048 13.8 0.7 0.39 10.9 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4253) Dynamin_N PF00350.23 EKX37304.1 - 0.00021 21.4 2.9 0.00033 20.8 0.0 2.5 2 1 0 2 2 2 1 Dynamin family Nitr_red_assoc PF09655.10 EKX37304.1 - 0.00062 20.4 1.4 0.42 11.2 0.7 2.5 2 0 0 2 2 2 2 Conserved nitrate reductase-associated protein (Nitr_red_assoc) Toprim_4 PF13662.6 EKX37304.1 - 0.0069 16.8 0.1 6.5 7.3 0.0 2.9 3 0 0 3 3 3 2 Toprim domain AIG1 PF04548.16 EKX37304.1 - 0.0082 15.5 2.3 1.6 8.0 0.1 2.5 3 0 0 3 3 3 2 AIG1 family MMR_HSR1 PF01926.23 EKX37304.1 - 0.013 15.5 0.1 0.051 13.7 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_5 PF07728.14 EKX37304.1 - 0.077 13.0 0.3 0.19 11.7 0.3 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Exonuc_VII_L PF02601.15 EKX37304.1 - 0.43 10.1 5.7 0.59 9.7 5.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2894 PF11445.8 EKX37304.1 - 0.48 10.9 7.5 0.22 12.0 5.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) Aida_N PF08910.10 EKX37304.1 - 0.85 10.0 4.8 0.51 10.7 1.1 2.3 1 1 2 3 3 3 0 Aida N-terminus Peptidase_C14 PF00656.22 EKX37305.1 - 2.7e-09 37.3 0.0 3.1e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Caspase domain RRM_1 PF00076.22 EKX37306.1 - 4.6e-11 42.4 0.0 9.5e-11 41.4 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EKX37306.1 - 0.00039 20.5 0.0 0.00055 20.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 EKX37306.1 - 0.00091 18.8 0.0 0.0026 17.4 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ion_trans PF00520.31 EKX37307.1 - 8.8e-31 107.0 23.4 1.6e-30 106.2 23.4 1.3 1 0 0 1 1 1 1 Ion transport protein CAP_N PF01213.19 EKX37308.1 - 1.7e-38 132.9 0.0 2.1e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal DUF572 PF04502.13 EKX37308.1 - 0.033 13.8 1.9 0.045 13.4 1.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) NAGLU_N PF12971.7 EKX37308.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain CobT PF06213.12 EKX37308.1 - 0.54 9.6 7.8 8.9 5.6 8.3 2.0 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT RNA_pol_3_Rpc31 PF11705.8 EKX37308.1 - 2.7 8.2 13.1 30 4.8 11.9 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Latarcin PF10279.9 EKX37308.1 - 4.6 7.7 9.6 1.4 9.3 1.0 2.7 1 1 1 2 2 2 0 Latarcin precursor Exo_endo_phos PF03372.23 EKX37309.1 - 1.5e-13 50.9 0.0 6.9e-13 48.7 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EKX37309.1 - 0.08 12.8 0.5 3 7.7 0.0 2.9 3 0 0 3 3 3 0 Endonuclease-reverse transcriptase Rx_N PF18052.1 EKX37309.1 - 1.8 8.9 4.1 4 7.8 0.2 2.7 3 0 0 3 3 3 0 Rx N-terminal domain Methyltransf_18 PF12847.7 EKX37310.1 - 2.3e-36 125.0 0.0 4.3e-36 124.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain TrmK PF04816.12 EKX37310.1 - 1.2e-33 116.4 0.1 2.5e-33 115.3 0.1 1.4 1 1 0 1 1 1 1 tRNA (adenine(22)-N(1))-methyltransferase MTS PF05175.14 EKX37310.1 - 0.015 14.9 0.1 0.023 14.2 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Met_10 PF02475.16 EKX37310.1 - 0.039 13.7 0.0 0.061 13.1 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein PCMT PF01135.19 EKX37310.1 - 0.083 12.6 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 EKX37310.1 - 0.089 12.2 0.6 0.21 11.0 0.2 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EKX37310.1 - 0.089 13.5 0.0 0.16 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PRELI PF04707.14 EKX37312.1 - 6.1e-19 68.4 0.0 7.3e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family SR-25 PF10500.9 EKX37312.1 - 0.41 10.2 7.6 0.49 10.0 7.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PDZ PF00595.24 EKX37313.1 - 1.1e-05 25.7 0.2 0.0013 19.0 0.1 2.7 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EKX37313.1 - 2e-05 24.3 0.2 0.00012 21.9 0.1 2.2 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX37313.1 - 0.0001 22.5 0.2 0.001 19.4 0.0 2.4 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 EKX37313.1 - 0.00049 20.0 0.0 0.0014 18.5 0.0 1.8 1 0 0 1 1 1 1 Tricorn protease PDZ domain KASH_CCD PF14662.6 EKX37313.1 - 0.002 18.0 16.9 0.024 14.4 12.4 2.4 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH bZIP_2 PF07716.15 EKX37313.1 - 0.0079 16.3 17.8 0.15 12.2 1.8 4.1 4 0 0 4 4 4 2 Basic region leucine zipper UPF0242 PF06785.11 EKX37313.1 - 0.027 14.6 8.8 0.045 13.9 8.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 EKX37313.1 - 0.089 12.6 13.9 4.1 7.2 1.6 4.2 3 1 1 4 4 4 0 Septum formation initiator bZIP_1 PF00170.21 EKX37313.1 - 0.14 12.2 0.2 0.14 12.2 0.2 3.7 4 0 0 4 4 4 0 bZIP transcription factor Cnn_1N PF07989.11 EKX37313.1 - 0.36 11.0 15.6 0.35 11.0 1.9 3.3 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 DUF641 PF04859.12 EKX37313.1 - 1 9.7 7.3 3.1 8.1 6.8 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) FAM76 PF16046.5 EKX37313.1 - 3.1 7.1 19.1 3.1 7.1 12.0 2.9 2 1 0 2 2 2 0 FAM76 protein DUF4201 PF13870.6 EKX37313.1 - 3.7 7.3 16.3 0.77 9.5 6.3 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) BST2 PF16716.5 EKX37313.1 - 5.2 7.7 13.5 0.33 11.6 2.0 3.2 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 HALZ PF02183.18 EKX37313.1 - 5.6 7.3 8.2 15 5.9 0.3 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper YabA PF06156.13 EKX37313.1 - 6.7 7.4 16.6 21 5.8 3.4 3.4 1 1 1 2 2 2 0 Initiation control protein YabA FapA PF03961.13 EKX37313.1 - 8.2 4.9 8.4 13 4.2 8.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A RRM_1 PF00076.22 EKX37316.1 - 6.2e-19 67.6 0.0 7.4e-19 67.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EKX37316.1 - 1.7e-06 28.1 0.0 2.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif DUF3592 PF12158.8 EKX37317.1 - 0.059 13.4 0.0 0.1 12.7 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) GBP PF02263.19 EKX37319.1 - 2.9e-27 95.6 0.0 3.2e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Hexapep PF00132.24 EKX37320.1 - 1.5e-15 56.2 4.7 4.7e-09 35.6 1.2 4.3 2 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EKX37320.1 - 0.00019 21.1 11.7 0.0054 16.5 4.3 3.5 1 1 2 3 3 3 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EKX37320.1 - 0.095 11.6 0.1 0.16 10.8 0.1 1.4 1 1 0 1 1 1 0 L-fucokinase Fapy_DNA_glyco PF01149.24 EKX37322.1 - 1.4e-10 41.8 0.0 2.1e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 EKX37322.1 - 2.1e-05 24.4 0.0 4.4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 EKX37322.1 - 0.043 12.6 0.0 0.07 11.9 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) AF0941-like PF14591.6 EKX37323.1 - 1.3 9.7 6.9 0.33 11.5 3.1 2.0 2 1 0 2 2 2 0 AF0941-like PH PF00169.29 EKX37324.1 - 0.032 14.8 0.0 0.065 13.7 0.0 1.5 1 0 0 1 1 1 0 PH domain K_channel_TID PF07941.11 EKX37324.1 - 0.52 10.8 8.4 1.3 9.5 8.4 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain PDZ_6 PF17820.1 EKX37325.1 - 2.6e-12 46.4 0.2 4.4e-12 45.7 0.2 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX37325.1 - 4.7e-09 36.4 0.1 7.7e-09 35.8 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX37325.1 - 8.3e-07 29.3 0.0 1.4e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain NusA_N PF08529.11 EKX37326.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 NusA N-terminal domain Pyr_redox_2 PF07992.14 EKX37327.1 - 6.1e-21 74.9 0.2 1.3e-20 73.9 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rhodanese PF00581.20 EKX37327.1 - 1.4e-10 41.6 0.0 4.3e-10 40.1 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain Pyr_redox_3 PF13738.6 EKX37327.1 - 1.9e-10 40.5 1.0 6.7e-06 25.6 0.1 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EKX37327.1 - 1.4e-09 38.3 2.7 0.00024 21.6 0.6 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EKX37327.1 - 2.4e-07 31.0 0.1 5.4e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain NAD_binding_9 PF13454.6 EKX37327.1 - 0.018 15.1 0.1 0.28 11.2 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 EKX37327.1 - 0.04 12.6 0.8 1.9 7.1 0.0 2.6 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_8 PF13450.6 EKX37327.1 - 0.14 12.4 0.0 0.38 11.0 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EKX37328.1 - 3.6e-07 29.7 0.0 0.0011 18.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EKX37328.1 - 1.1e-06 28.8 0.0 2.7e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EKX37328.1 - 0.00014 21.1 0.2 0.16 11.0 0.0 2.9 3 0 0 3 3 3 2 FAD binding domain GIDA PF01134.22 EKX37328.1 - 0.00099 18.3 0.4 0.0036 16.4 0.1 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 EKX37328.1 - 0.0013 19.3 1.4 0.16 12.5 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EKX37328.1 - 0.0055 16.0 0.1 0.072 12.3 0.1 2.4 3 0 0 3 3 3 1 FAD binding domain GMC_oxred_N PF00732.19 EKX37328.1 - 0.026 13.9 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 GMC oxidoreductase HI0933_like PF03486.14 EKX37328.1 - 0.026 13.2 0.2 0.11 11.1 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.7 EKX37328.1 - 0.035 13.5 1.4 0.36 10.1 0.3 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 EKX37328.1 - 0.053 13.4 0.2 0.086 12.7 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EKX37328.1 - 0.071 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 EKX37328.1 - 0.093 12.1 0.0 0.35 10.2 0.0 1.8 2 0 0 2 2 2 0 ThiF family Terminase_2 PF03592.16 EKX37329.1 - 0.044 14.3 2.4 0.08 13.4 2.3 1.4 1 1 0 1 1 1 0 Terminase small subunit PRP3 PF08572.10 EKX37329.1 - 5 6.8 10.8 11 5.7 10.8 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 3 (PRP3) ETAA1 PF15350.6 EKX37330.1 - 0.0041 15.5 2.3 0.0058 15.0 2.3 1.2 1 0 0 1 1 1 1 Ewing's tumour-associated antigen 1 homologue CDC45 PF02724.14 EKX37330.1 - 0.027 12.8 4.4 0.038 12.3 4.4 1.2 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 EKX37330.1 - 0.043 12.4 1.7 0.059 11.9 1.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PI3K_1B_p101 PF10486.9 EKX37330.1 - 1.3 6.7 6.3 1.9 6.1 5.8 1.4 1 1 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PDZ_6 PF17820.1 EKX37331.1 - 4.2e-07 29.7 0.0 1.3e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX37331.1 - 0.00014 22.1 0.0 0.00029 21.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain TpcC PF12642.7 EKX37331.1 - 0.15 11.8 0.5 0.28 10.9 0.5 1.4 1 0 0 1 1 1 0 Conjugative transposon protein TcpC Tau95_N PF17682.1 EKX37331.1 - 1.7 8.9 4.2 6.8 6.9 4.0 2.0 1 1 0 1 1 1 0 Tau95 Triple barrel domain PRKCSH PF07915.13 EKX37332.1 - 1.1e-08 35.9 0.3 2.4e-08 34.9 0.3 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Aldo_ket_red PF00248.21 EKX37333.1 - 5.1e-70 236.0 0.0 6.6e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Terminase_1 PF03354.15 EKX37333.1 - 0.0051 15.4 0.0 0.015 13.9 0.0 1.6 2 0 0 2 2 2 1 Phage Terminase PHD PF00628.29 EKX37335.1 - 7.5e-08 32.2 10.7 7.5e-08 32.2 10.7 2.5 2 0 0 2 2 2 1 PHD-finger ARID PF01388.21 EKX37335.1 - 9.4e-06 26.2 0.0 2.4e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHF5 PF03660.14 EKX37335.1 - 0.056 13.7 7.2 0.14 12.4 4.1 2.4 2 0 0 2 2 2 0 PHF5-like protein Pkinase PF00069.25 EKX37336.1 - 5.2e-18 65.4 0.0 6.2e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX37336.1 - 0.021 14.1 0.1 0.062 12.6 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase PhyH PF05721.13 EKX37337.1 - 0.0018 18.5 0.0 0.014 15.7 0.0 2.0 1 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) zf-RING_2 PF13639.6 EKX37339.1 - 8.4e-13 48.4 10.9 1.4e-12 47.7 10.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EKX37339.1 - 9e-11 41.3 4.2 9e-11 41.3 4.2 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EKX37339.1 - 5.2e-08 32.6 9.3 8.7e-08 31.9 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX37339.1 - 2.3e-07 30.6 10.4 3.6e-07 30.0 10.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX37339.1 - 5.3e-06 26.3 3.5 9.8e-06 25.5 3.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EKX37339.1 - 6.3e-06 26.4 11.1 6.3e-06 26.4 11.1 2.1 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EKX37339.1 - 0.0006 19.7 9.0 0.00086 19.2 9.0 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EKX37339.1 - 0.015 15.1 8.5 0.022 14.6 8.5 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EKX37339.1 - 0.031 14.3 5.9 0.074 13.1 5.9 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EKX37339.1 - 0.057 13.6 7.6 0.13 12.5 7.7 1.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 EKX37339.1 - 0.1 12.7 7.5 0.3 11.2 7.5 1.8 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 EKX37339.1 - 0.75 10.0 8.0 1.8 8.8 8.0 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain FAD_binding_6 PF00970.24 EKX37340.1 - 1.3e-29 102.4 0.0 1.9e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EKX37340.1 - 1.6e-29 102.7 0.0 4.5e-29 101.3 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EKX37340.1 - 0.00074 19.7 0.0 0.067 13.3 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 EKX37340.1 - 0.0045 17.2 0.0 0.0084 16.3 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain Peptidase_S41 PF03572.18 EKX37341.1 - 1.2e-47 161.6 0.1 2.1e-47 160.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 EKX37341.1 - 5.6e-08 32.5 0.0 1.4e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX37341.1 - 8.2e-07 29.3 0.0 1.6e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX37341.1 - 0.12 12.7 0.0 0.35 11.3 0.0 1.8 1 0 0 1 1 1 0 PDZ domain EF-hand_1 PF00036.32 EKX37342.1 - 1.4e-09 36.8 1.3 0.00026 20.3 1.4 3.2 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EKX37342.1 - 2.6e-09 37.4 0.3 1.1e-08 35.4 0.6 1.9 2 0 0 2 2 2 1 EF-hand domain pair Pribosyltran_N PF13793.6 EKX37342.1 - 4.8e-08 32.9 0.0 3.1e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 EKX37342.1 - 8.7e-08 31.8 0.0 2.6e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain EF-hand_6 PF13405.6 EKX37342.1 - 9.6e-08 31.4 0.6 0.037 14.0 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 EKX37342.1 - 3.4e-07 30.0 2.6 3.9e-07 29.8 0.9 2.1 2 0 0 2 2 2 1 EF-hand domain pair Pribosyl_synth PF14572.6 EKX37342.1 - 4.6e-06 26.8 0.0 8e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain EF-hand_5 PF13202.6 EKX37342.1 - 0.00037 19.9 0.7 0.0047 16.4 0.5 2.5 2 0 0 2 2 2 1 EF hand HEAT_2 PF13646.6 EKX37344.1 - 8.5e-07 29.3 6.9 2.4e-05 24.6 0.9 3.7 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 EKX37344.1 - 2.4e-05 24.7 5.1 0.009 16.5 0.3 3.1 2 1 0 2 2 2 2 HEAT-like repeat Arm PF00514.23 EKX37344.1 - 0.02 14.9 9.7 0.25 11.4 0.1 4.7 6 1 0 6 6 6 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EKX37344.1 - 0.051 13.9 7.7 14 6.3 0.0 5.0 4 1 0 4 4 4 0 HEAT repeat UPF0253 PF06786.12 EKX37344.1 - 0.59 10.5 14.0 1.7 9.0 0.2 4.4 4 1 0 4 4 4 0 Uncharacterised protein family (UPF0253) HMG_box PF00505.19 EKX37346.1 - 2.5e-10 40.6 0.0 1e-09 38.7 0.0 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EKX37346.1 - 1.2e-09 38.7 0.0 3.5e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 HMG-box domain Cob_adeno_trans PF01923.18 EKX37346.1 - 0.18 11.9 0.5 0.62 10.2 0.2 1.8 2 0 0 2 2 2 0 Cobalamin adenosyltransferase CBM_20 PF00686.19 EKX37347.1 - 1.2e-24 86.1 0.1 1.5e-09 37.6 0.0 3.5 3 1 0 3 3 3 3 Starch binding domain DSPc PF00782.20 EKX37347.1 - 1.6e-12 47.4 0.0 2.5e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 EKX37347.1 - 5.7e-06 26.1 0.0 1.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) AMPK1_CBM PF16561.5 EKX37347.1 - 0.01 16.1 0.0 0.26 11.6 0.0 2.5 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase Y_phosphatase PF00102.27 EKX37347.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PDZ_2 PF13180.6 EKX37348.1 - 5.9e-19 68.2 0.1 8.5e-09 35.6 0.1 2.8 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EKX37348.1 - 6.8e-16 57.9 0.2 8.2e-08 32.0 0.3 2.5 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 EKX37348.1 - 6.1e-10 39.3 0.0 0.00062 20.1 0.0 2.6 2 0 0 2 2 2 2 PDZ domain DUF3886 PF13025.6 EKX37348.1 - 0.022 15.0 2.9 0.077 13.2 2.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) DUF4718 PF15842.5 EKX37348.1 - 1.1 9.1 4.1 0.79 9.5 1.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) GTP_cyclohydro2 PF00925.20 EKX37351.1 - 6.4e-55 185.2 0.0 8e-55 184.9 0.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase II CSN5_C PF18323.1 EKX37351.1 - 0.14 13.1 0.1 0.26 12.2 0.1 1.4 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain KOW PF00467.29 EKX37351.1 - 0.65 10.0 4.3 0.37 10.8 2.2 1.7 2 0 0 2 2 2 0 KOW motif PX PF00787.24 EKX37352.1 - 1.4e-15 57.2 0.1 2.2e-15 56.6 0.1 1.3 1 0 0 1 1 1 1 PX domain HMG_box_2 PF09011.10 EKX37353.1 - 6.6e-08 33.0 0.0 1.3e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 EKX37353.1 - 1.7e-06 28.4 0.1 1.7e-06 28.4 0.1 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box YABBY PF04690.13 EKX37353.1 - 7.2e-05 23.4 0.3 0.00014 22.4 0.0 1.5 2 0 0 2 2 2 1 YABBY protein PDZ_6 PF17820.1 EKX37354.1 - 3.1e-08 33.3 0.2 7.2e-08 32.2 0.2 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX37354.1 - 9.3e-07 29.1 1.5 1.9e-06 28.1 0.2 2.2 2 1 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX37354.1 - 4.5e-06 26.9 0.2 9.6e-06 25.9 0.2 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX37354.1 - 0.015 15.2 0.0 0.043 13.8 0.0 1.8 1 0 0 1 1 1 0 Tricorn protease PDZ domain MCPsignal PF00015.21 EKX37354.1 - 0.73 9.6 9.6 0.23 11.3 1.7 2.4 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Pex24p PF06398.11 EKX37354.1 - 1.6 7.6 4.7 0.78 8.7 2.8 1.5 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Spc7 PF08317.11 EKX37354.1 - 3.5 6.4 37.9 4.9 5.9 3.4 2.5 1 1 2 3 3 3 0 Spc7 kinetochore protein Methyltransf_23 PF13489.6 EKX37355.1 - 0.032 14.1 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Thioredoxin PF00085.20 EKX37356.1 - 2.8e-07 30.5 0.0 4.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EKX37356.1 - 2.3e-05 24.8 0.0 4.4e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 EKX37356.1 - 0.0015 18.4 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 EKX37356.1 - 0.033 14.4 0.1 0.055 13.6 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin-like HyaE PF07449.11 EKX37356.1 - 0.048 13.6 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 EKX37356.1 - 0.072 13.4 1.1 1.9 8.8 0.1 2.9 1 1 1 3 3 3 0 Thioredoxin-like ADH_N_2 PF16884.5 EKX37357.1 - 3e-31 107.5 0.0 5.7e-31 106.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EKX37357.1 - 1.5e-22 80.0 0.0 2.2e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EKX37357.1 - 4e-08 34.4 0.0 6.6e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Thioredoxin_8 PF13905.6 EKX37358.1 - 1.5e-23 82.9 0.0 1.8e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 EKX37358.1 - 0.00014 21.8 0.1 0.00023 21.1 0.1 1.5 1 1 1 2 2 2 1 Thioredoxin AhpC-TSA PF00578.21 EKX37358.1 - 0.0018 18.2 0.0 0.0025 17.7 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family NESP55 PF06390.12 EKX37359.1 - 0.013 15.1 1.8 0.023 14.3 1.8 1.4 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Trypan_PARP PF05887.11 EKX37359.1 - 0.033 14.2 1.8 0.053 13.5 1.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TetR_C_20 PF17925.1 EKX37360.1 - 1.4 9.2 3.6 0.97 9.8 0.0 2.6 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Host_attach PF10116.9 EKX37360.1 - 2.6 8.6 0.0 2.6 8.6 0.0 3.3 4 0 0 4 4 4 0 Protein required for attachment to host cells Gemin7 PF11095.8 EKX37361.1 - 2.5e-16 59.3 0.0 2.7e-16 59.2 0.0 1.0 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) Pkinase PF00069.25 EKX37362.1 - 2.4e-67 227.1 0.0 2.7e-67 226.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX37362.1 - 5.3e-46 157.0 0.0 6.3e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX37362.1 - 5.3e-05 22.7 0.0 8.9e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EKX37362.1 - 0.0082 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EKX37362.1 - 0.0085 14.9 0.0 0.031 13.1 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 EKX37362.1 - 0.029 13.3 0.2 0.16 10.9 0.2 1.9 1 1 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EKX37362.1 - 0.037 13.1 0.2 0.075 12.1 0.0 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 tRNA-synt_1c PF00749.21 EKX37362.1 - 0.082 11.8 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain MBOAT PF03062.19 EKX37363.1 - 1.8e-15 57.2 14.7 2e-15 57.0 14.7 1.1 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Raffinose_syn PF05691.12 EKX37364.1 - 2e-93 313.6 0.0 2.5e-93 313.2 0.0 1.1 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 FAST_1 PF06743.15 EKX37364.1 - 0.77 9.7 3.6 1.3 9.0 2.3 1.9 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 DSPc PF00782.20 EKX37365.1 - 6.5e-30 103.7 0.1 8.7e-30 103.2 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 EKX37365.1 - 0.021 14.4 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 EKX37365.1 - 0.049 13.2 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase U3_assoc_6 PF08640.11 EKX37367.1 - 2.7e-25 88.3 6.5 4.1e-25 87.7 6.5 1.3 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 Sigma70_r1_2 PF00140.20 EKX37367.1 - 0.26 11.3 2.4 0.37 10.8 0.6 2.1 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 Abhydrolase_2 PF02230.16 EKX37368.1 - 2.2e-33 115.9 0.0 2.7e-33 115.6 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EKX37368.1 - 6.8e-05 23.6 0.1 7.9e-05 23.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EKX37368.1 - 0.00035 19.9 0.2 0.19 11.0 0.0 2.6 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EKX37368.1 - 0.0049 16.4 0.0 0.024 14.1 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 EKX37368.1 - 0.0074 15.9 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 EKX37368.1 - 0.015 15.2 0.1 0.21 11.4 0.0 2.0 1 1 0 2 2 2 0 alpha/beta hydrolase fold FSH1 PF03959.13 EKX37368.1 - 0.027 14.2 0.0 0.078 12.6 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Thioesterase PF00975.20 EKX37368.1 - 0.072 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain DUF4201 PF13870.6 EKX37369.1 - 2.9e-16 59.7 21.5 2.9e-16 59.7 21.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) TACC_C PF05010.14 EKX37369.1 - 0.0032 17.3 18.5 0.0032 17.3 18.5 2.3 1 1 1 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal HGTP_anticodon PF03129.20 EKX37369.1 - 0.019 15.1 0.1 0.019 15.1 0.1 2.5 3 0 0 3 3 3 0 Anticodon binding domain SlyX PF04102.12 EKX37369.1 - 0.15 12.7 0.5 0.15 12.7 0.5 5.0 4 1 1 5 5 5 0 SlyX DUF2344 PF10105.9 EKX37369.1 - 1.1 9.1 12.5 0.069 13.0 6.2 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) Myb_DNA-binding PF00249.31 EKX37371.1 - 2e-08 34.3 0.0 1e-07 32.0 0.0 2.0 1 1 0 1 1 1 1 Myb-like DNA-binding domain Peptidase_M14 PF00246.24 EKX37372.1 - 5.8e-36 124.8 0.0 9.1e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF2817 PF10994.8 EKX37372.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) HR1 PF02185.16 EKX37372.1 - 0.11 12.6 1.2 0.3 11.2 1.0 1.7 2 0 0 2 2 2 0 Hr1 repeat CDC45 PF02724.14 EKX37372.1 - 0.54 8.5 10.1 0.76 8.0 10.1 1.1 1 0 0 1 1 1 0 CDC45-like protein CNDH2_C PF16858.5 EKX37372.1 - 2.3 8.0 7.2 4.1 7.2 7.2 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nop14 PF04147.12 EKX37372.1 - 3 5.9 19.1 4.8 5.3 19.1 1.2 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 EKX37372.1 - 7.9 4.9 16.0 13 4.2 16.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Utp14 PF04615.13 EKX37372.1 - 9.6 4.6 8.6 16 3.9 8.6 1.3 1 0 0 1 1 1 0 Utp14 protein SecG PF03840.14 EKX37373.1 - 0.097 12.8 1.4 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 Preprotein translocase SecG subunit Atg14 PF10186.9 EKX37374.1 - 1.3e-05 24.5 13.3 0.00025 20.2 13.4 2.2 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 YejG PF13989.6 EKX37374.1 - 0.018 15.5 0.5 0.038 14.4 0.5 1.6 1 0 0 1 1 1 0 YejG-like protein WD40 PF00400.32 EKX37375.1 - 1.9e-19 69.6 13.0 0.00024 21.9 0.0 7.4 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX37375.1 - 2.3e-07 31.0 0.8 1.1 9.7 0.1 5.2 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_1 PF00036.32 EKX37375.1 - 4.7e-06 25.8 0.5 5.8e-05 22.4 0.1 3.0 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EKX37375.1 - 1.1e-05 25.8 0.4 2.9e-05 24.4 0.4 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX37375.1 - 3.8e-05 23.3 0.5 0.00025 20.7 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 EKX37375.1 - 0.0087 15.5 0.3 0.0087 15.5 0.3 2.7 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 EKX37375.1 - 0.024 14.5 0.0 0.41 10.5 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair Nup160 PF11715.8 EKX37375.1 - 0.029 13.0 2.0 2.4 6.7 0.4 3.4 1 1 2 3 3 3 0 Nucleoporin Nup120/160 AAA_14 PF13173.6 EKX37377.1 - 0.0022 18.0 0.0 0.0082 16.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EKX37377.1 - 0.007 16.9 0.0 0.023 15.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EKX37377.1 - 0.012 15.4 0.1 0.08 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EKX37377.1 - 0.024 14.3 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EKX37377.1 - 0.031 14.6 0.1 0.11 12.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EKX37377.1 - 0.035 13.7 0.1 0.1 12.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EKX37377.1 - 0.035 14.5 0.0 0.1 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EKX37377.1 - 0.064 13.7 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EKX37377.1 - 0.067 12.9 0.2 0.45 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EKX37377.1 - 0.13 11.9 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Pkinase PF00069.25 EKX37382.1 - 5.6e-38 130.8 0.0 3e-36 125.1 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EKX37382.1 - 1.2e-32 113.2 0.0 2.2e-32 112.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX37382.1 - 0.0056 16.6 0.1 0.0091 15.9 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FYVE PF01363.21 EKX37383.1 - 1.3e-22 79.7 13.7 1.5e-22 79.5 13.7 1.0 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 EKX37383.1 - 0.0031 17.7 11.8 0.005 17.1 11.8 1.4 1 1 0 1 1 1 1 FYVE-type zinc finger DZR PF12773.7 EKX37383.1 - 0.21 11.6 14.2 50 4.0 14.2 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-B_box PF00643.24 EKX37383.1 - 0.4 10.9 15.7 1.9 8.7 12.0 2.7 2 1 0 2 2 2 0 B-box zinc finger IBR PF01485.21 EKX37383.1 - 0.47 10.7 15.0 0.13 12.5 11.6 1.7 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain UNC-79 PF14776.6 EKX37383.1 - 5.1 5.7 10.2 5.2 5.7 10.2 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 zf-AN1 PF01428.16 EKX37383.1 - 7.8 6.8 18.9 0.84 9.9 10.8 2.6 1 1 2 3 3 3 0 AN1-like Zinc finger PolC_DP2 PF03833.13 EKX37383.1 - 9 4.0 7.4 9.6 3.9 7.4 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Nuc_sug_transp PF04142.15 EKX37384.1 - 2.6e-29 102.4 18.3 3.4e-29 102.0 18.3 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EKX37384.1 - 8.6e-07 29.2 33.0 0.00044 20.4 14.7 2.5 2 1 0 2 2 2 2 EamA-like transporter family PIG-P PF08510.12 EKX37384.1 - 0.32 10.9 9.4 0.7 9.8 1.0 3.2 2 1 0 2 2 2 0 PIG-P Glyco_hydr_116N PF12215.8 EKX37385.1 - 4.2e-22 79.0 0.1 1.1e-21 77.6 0.0 1.7 2 0 0 2 2 2 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term DUF608 PF04685.13 EKX37385.1 - 9.5e-13 48.0 0.4 7.3e-12 45.1 0.3 2.2 2 1 0 2 2 2 1 Glycosyl-hydrolase family 116, catalytic region EGF_Tenascin PF18720.1 EKX37385.1 - 0.068 13.2 0.1 0.19 11.8 0.1 1.8 1 0 0 1 1 1 0 Tenascin EGF domain Cation_efflux PF01545.21 EKX37387.1 - 3.2e-27 95.5 0.2 4.5e-27 95.1 0.2 1.2 1 0 0 1 1 1 1 Cation efflux family DUF778 PF05608.12 EKX37388.1 - 0.06 13.7 0.1 0.077 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF778) BRD4_CDT PF17105.5 EKX37388.1 - 0.72 9.5 0.0 0.72 9.5 0.0 2.8 4 0 0 4 4 4 0 C-terminal domain of bromodomain protein 4 ODR4-like PF14778.6 EKX37389.1 - 2.8e-46 158.2 0.0 3.5e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 Olfactory receptor 4-like Zeta_toxin PF06414.12 EKX37390.1 - 1.7e-07 30.7 1.0 0.012 14.8 0.5 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.6 EKX37390.1 - 9.2e-07 29.1 0.5 0.025 14.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EKX37390.1 - 0.00063 20.3 0.0 0.0016 19.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EKX37390.1 - 0.0018 18.7 0.1 0.0074 16.7 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 EKX37390.1 - 0.0052 16.7 0.0 0.014 15.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EKX37390.1 - 0.0052 17.1 0.0 0.045 14.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 EKX37390.1 - 0.0058 16.6 0.0 0.0097 15.8 0.0 1.3 1 0 0 1 1 1 1 P-loop Nucleotide Kinase3 Viral_helicase1 PF01443.18 EKX37390.1 - 0.0072 16.1 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EKX37390.1 - 0.01 15.1 0.1 0.046 13.0 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 EKX37390.1 - 0.015 14.5 0.0 0.04 13.1 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 EKX37390.1 - 0.016 15.0 0.0 0.049 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EKX37390.1 - 0.021 15.2 0.0 0.021 15.2 0.0 2.3 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.14 EKX37390.1 - 0.031 14.3 0.0 0.071 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 EKX37390.1 - 0.035 14.0 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 EKX37390.1 - 0.038 14.4 0.8 0.085 13.3 0.2 2.2 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) KASH PF10541.9 EKX37390.1 - 0.094 13.0 6.8 0.24 11.7 6.8 1.7 1 0 0 1 1 1 0 Nuclear envelope localisation domain AAA_17 PF13207.6 EKX37390.1 - 0.11 12.9 0.1 0.35 11.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 EKX37390.1 - 0.11 13.0 0.8 0.3 11.6 0.2 2.1 2 1 0 2 2 1 0 ABC transporter HTH_Tnp_Tc5 PF03221.16 EKX37390.1 - 0.13 12.3 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain YfhO PF09586.10 EKX37390.1 - 0.19 9.9 4.7 0.27 9.4 4.7 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO p53-inducible11 PF14936.6 EKX37390.1 - 1.3 9.1 5.4 28 4.7 3.9 2.4 2 0 0 2 2 2 0 Tumour protein p53-inducible protein 11 DUF3439 PF11921.8 EKX37390.1 - 3.9 7.5 11.7 10 6.1 11.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Cupin_8 PF13621.6 EKX37391.1 - 2.7 7.7 5.5 75 2.9 5.0 2.4 2 1 0 2 2 2 0 Cupin-like domain ATPgrasp_N PF18130.1 EKX37392.1 - 9.1e-07 29.4 0.0 1.7e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp PF02222.22 EKX37392.1 - 0.017 14.7 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Rab5ip PF07019.12 EKX37392.1 - 0.05 14.2 0.7 0.12 13.0 0.7 1.6 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) RimK PF08443.11 EKX37392.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Kinesin PF00225.23 EKX37393.1 - 1.6e-59 201.5 0.3 9.3e-56 189.2 0.2 2.1 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 EKX37393.1 - 1.3e-21 77.1 0.0 2.8e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding WD40_alt PF14077.6 EKX37394.1 - 0.053 13.4 3.0 0.75 9.7 0.2 2.4 2 0 0 2 2 2 0 Alternative WD40 repeat motif Tim54 PF11711.8 EKX37396.1 - 4.2 6.1 34.9 1.5 7.5 2.5 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Trypan_PARP PF05887.11 EKX37396.1 - 5 7.1 18.5 0.034 14.1 9.5 1.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) RPN2_C PF18004.1 EKX37396.1 - 5.4 6.9 39.3 3.3 7.6 5.0 2.4 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain GAS PF13851.6 EKX37397.1 - 0.033 13.6 48.4 0.38 10.1 26.4 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding MscS_porin PF12795.7 EKX37397.1 - 0.93 9.0 51.1 0.26 10.8 46.6 2.2 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF1664 PF07889.12 EKX37397.1 - 2 8.5 18.1 1.6 8.8 2.3 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) SHE3 PF17078.5 EKX37397.1 - 3.8 7.2 29.6 3.7 7.2 27.2 2.0 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 EMP24_GP25L PF01105.24 EKX37397.1 - 7.1 6.5 16.0 2.4 8.1 5.5 2.8 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD BRE1 PF08647.11 EKX37397.1 - 9.5 6.4 35.5 0.045 13.8 11.6 3.8 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase TPR_MLP1_2 PF07926.12 EKX37398.1 - 0.0059 16.7 7.1 0.0059 16.7 7.1 6.7 2 2 5 7 7 7 1 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.21 EKX37398.1 - 0.014 15.5 1.6 0.014 15.5 1.6 8.2 5 1 3 8 8 8 0 bZIP transcription factor Fib_alpha PF08702.10 EKX37398.1 - 0.17 12.1 51.9 0.08 13.1 4.3 5.4 2 1 3 5 5 5 0 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.9 EKX37398.1 - 0.52 10.7 56.1 0.077 13.3 3.2 7.0 4 2 3 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 EKX37398.1 - 0.64 10.1 44.3 0.57 10.2 3.9 5.9 1 1 4 6 6 6 0 Protein of unknown function (DUF1664) Filament PF00038.21 EKX37398.1 - 0.99 8.9 72.6 0.37 10.3 45.3 4.2 1 1 1 2 2 2 0 Intermediate filament protein TMEM95 PF15203.6 EKX37398.1 - 1.6 8.4 4.6 21 4.7 0.2 2.8 2 0 0 2 2 2 0 TMEM95 family CCT_2 PF09425.10 EKX37398.1 - 1.7 8.6 4.9 9.2 6.3 0.6 2.8 2 0 0 2 2 2 0 Divergent CCT motif AAA_13 PF13166.6 EKX37398.1 - 3.7 6.1 58.9 0.053 12.2 25.6 2.5 1 1 1 2 2 2 0 AAA domain AvrLm4-7 PF18661.1 EKX37398.1 - 5.4 8.1 7.1 12 7.0 0.4 3.3 3 1 1 4 4 4 0 Avirulence Effector AvrLm4-7 MORN PF02493.20 EKX37399.1 - 1.2e-21 75.3 18.7 5.9e-09 35.3 1.1 3.2 3 0 0 3 3 3 3 MORN repeat Ank_5 PF13857.6 EKX37400.1 - 1.1e-25 89.3 0.9 6e-11 42.4 0.1 2.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX37400.1 - 5.1e-19 68.4 1.8 3.3e-05 24.3 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EKX37400.1 - 6.9e-19 67.4 1.8 2e-06 27.9 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 EKX37400.1 - 1.2e-18 67.5 3.5 5.1e-10 39.8 0.5 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX37400.1 - 3e-10 39.4 3.4 0.084 13.5 0.0 4.5 5 0 0 5 5 5 3 Ankyrin repeat DUF930 PF06059.12 EKX37401.1 - 6.7 7.3 11.1 37 5.0 3.8 2.6 1 1 1 2 2 2 0 Domain of Unknown Function (DUF930) DUF2529 PF10740.9 EKX37401.1 - 10 5.8 10.9 39 3.8 0.8 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF2529) HWE_HK PF07536.14 EKX37402.1 - 0.076 13.7 0.1 0.09 13.5 0.1 1.1 1 0 0 1 1 1 0 HWE histidine kinase H_PPase PF03030.16 EKX37404.1 - 2e-227 757.0 37.4 4.2e-209 696.4 30.3 2.2 2 0 0 2 2 2 2 Inorganic H+ pyrophosphatase Rotamase_3 PF13616.6 EKX37404.1 - 0.17 12.5 0.7 0.41 11.2 0.1 2.0 2 0 0 2 2 2 0 PPIC-type PPIASE domain GPI2 PF06432.11 EKX37404.1 - 4.7 6.6 12.0 7.6 5.9 2.7 3.6 4 1 0 4 4 4 0 Phosphatidylinositol N-acetylglucosaminyltransferase TIP49 PF06068.13 EKX37406.1 - 2.1e-169 563.3 0.4 2.5e-169 563.0 0.4 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EKX37406.1 - 6.2e-22 77.5 0.0 1.7e-21 76.1 0.0 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain RuvB_N PF05496.12 EKX37406.1 - 1.4e-09 37.9 0.1 1.8e-06 27.8 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 EKX37406.1 - 4.7e-09 36.8 0.1 9.2e-06 26.1 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EKX37406.1 - 6.8e-05 23.2 0.1 0.089 13.1 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EKX37406.1 - 0.00092 19.2 0.1 0.2 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EKX37406.1 - 0.0023 17.3 0.5 0.072 12.5 0.2 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EKX37406.1 - 0.0026 18.1 0.0 0.021 15.2 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 EKX37406.1 - 0.0055 17.0 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EKX37406.1 - 0.0077 15.8 0.6 0.018 14.7 0.3 1.7 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EKX37406.1 - 0.011 15.5 0.1 5.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain ResIII PF04851.15 EKX37406.1 - 0.017 15.1 0.1 0.78 9.7 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 EKX37406.1 - 0.027 14.0 0.1 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_19 PF13245.6 EKX37406.1 - 0.037 14.4 3.0 1.3 9.4 3.0 2.4 1 1 0 1 1 1 0 AAA domain DnaB_C PF03796.15 EKX37406.1 - 0.041 13.2 0.0 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_33 PF13671.6 EKX37406.1 - 0.073 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EKX37406.1 - 0.078 13.5 0.0 0.29 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EKX37406.1 - 0.097 11.9 0.2 0.18 11.0 0.2 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.9 EKX37406.1 - 0.098 11.9 0.1 0.2 10.9 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RVT_3 PF13456.6 EKX37407.1 - 2.1e-08 34.0 1.2 0.00015 21.6 0.1 2.5 2 1 1 3 3 3 2 Reverse transcriptase-like DUF5449 PF17528.2 EKX37407.1 - 0.0092 15.8 0.2 0.01 15.6 0.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5449) DUF4508 PF14969.6 EKX37408.1 - 0.055 13.7 0.3 0.13 12.6 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4508) zf-C4 PF00105.18 EKX37408.1 - 0.059 13.8 1.3 0.11 13.0 1.3 1.4 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) DUF2804 PF10974.8 EKX37409.1 - 0.084 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2804) ILVD_EDD PF00920.21 EKX37411.1 - 2.1e-216 719.6 3.7 2.4e-216 719.3 3.7 1.0 1 0 0 1 1 1 1 Dehydratase family PSK PF06404.12 EKX37413.1 - 0.035 15.1 1.4 0.035 15.1 1.4 2.2 2 2 0 2 2 2 0 Phytosulfokine precursor protein (PSK) DUF647 PF04884.14 EKX37414.1 - 1.9e-60 204.5 0.4 2.7e-60 204.0 0.4 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis AAA_26 PF13500.6 EKX37415.1 - 1.9e-39 135.6 0.1 2.8e-39 135.0 0.1 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EKX37415.1 - 4.8e-10 39.6 0.1 1.5e-08 34.7 0.0 2.7 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 EKX37415.1 - 0.0033 16.9 0.2 0.012 15.0 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF1611 PF07755.11 EKX37415.1 - 0.012 14.9 2.0 0.1 11.8 0.1 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1611_C) P-loop domain CobA_CobO_BtuR PF02572.15 EKX37415.1 - 0.14 12.4 1.0 0.36 11.1 0.5 1.9 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Dus PF01207.17 EKX37416.1 - 1.2e-43 149.3 0.0 1.5e-43 149.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Glyco_tran_28_C PF04101.16 EKX37417.1 - 3e-20 72.8 0.1 8e-20 71.5 0.1 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain NAD_binding_3 PF03447.16 EKX37417.1 - 0.039 14.6 0.1 0.047 14.3 0.1 1.2 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Csm1_N PF18504.1 EKX37417.1 - 0.072 13.4 0.0 0.22 11.9 0.0 1.8 2 0 0 2 2 2 0 Csm1 N-terminal domain Herpes_BBRF1 PF04793.12 EKX37417.1 - 0.12 11.3 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 BRRF1-like protein C1_1 PF00130.22 EKX37418.1 - 0.00075 19.3 8.2 0.0017 18.2 8.2 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.11 EKX37418.1 - 0.055 13.8 2.9 0.13 12.6 2.9 1.6 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 EKX37418.1 - 0.091 12.7 6.6 0.19 11.7 6.6 1.5 1 0 0 1 1 1 0 PHD-finger Ank_4 PF13637.6 EKX37419.1 - 8.7e-19 67.6 2.1 5e-11 42.9 0.2 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Methyltransf_16 PF10294.9 EKX37419.1 - 9.5e-18 64.5 0.0 1.7e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Ank_2 PF12796.7 EKX37419.1 - 1.7e-17 63.8 2.0 8.9e-14 51.8 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EKX37419.1 - 1.2e-15 57.2 0.9 6.3e-05 23.2 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EKX37419.1 - 1.3e-12 46.6 0.4 0.0021 18.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EKX37419.1 - 1.2e-07 31.8 1.7 0.0028 17.9 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) PrmA PF06325.13 EKX37419.1 - 0.025 14.0 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EKX37419.1 - 0.057 14.1 0.0 0.13 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EKX37419.1 - 0.077 12.5 0.0 0.21 11.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Met_10 PF02475.16 EKX37419.1 - 0.22 11.3 0.0 0.35 10.6 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein RteC PF09357.10 EKX37419.1 - 0.26 11.0 0.0 0.52 10.0 0.0 1.4 1 0 0 1 1 1 0 RteC protein LSM14 PF12701.7 EKX37420.1 - 1.5e-34 117.9 0.0 1.7e-34 117.7 0.0 1.0 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 EKX37420.1 - 1e-09 38.4 0.0 1.1e-09 38.3 0.0 1.0 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF2205 PF10224.9 EKX37421.1 - 0.00069 19.6 1.6 0.0029 17.6 1.6 2.0 1 0 0 1 1 1 1 Short coiled-coil protein YabA PF06156.13 EKX37421.1 - 0.0082 16.8 4.3 0.0082 16.8 4.3 2.5 2 1 0 2 2 2 1 Initiation control protein YabA DivIC PF04977.15 EKX37421.1 - 0.013 15.2 0.6 0.013 15.2 0.6 3.0 4 0 0 4 4 4 0 Septum formation initiator TSC22 PF01166.18 EKX37421.1 - 0.058 13.7 2.0 0.13 12.6 2.0 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family PikAIV_N PF18605.1 EKX37421.1 - 6.6 6.4 8.1 20 4.9 0.0 2.8 2 1 1 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain zf-ribbon_3 PF13248.6 EKX37422.1 - 0.0015 17.9 1.1 0.0033 16.8 1.1 1.6 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 EKX37422.1 - 0.023 14.7 0.5 0.054 13.5 0.5 1.6 1 0 0 1 1 1 0 Double zinc ribbon Auto_anti-p27 PF06677.12 EKX37422.1 - 0.032 14.4 3.0 0.097 12.8 2.9 1.9 1 1 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DNA_RNApol_7kD PF03604.13 EKX37422.1 - 0.051 13.3 0.5 1.5 8.6 0.1 2.3 1 1 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit DUF2614 PF11023.8 EKX37422.1 - 0.059 13.5 0.2 0.12 12.4 0.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon containing domain zf-ISL3 PF14690.6 EKX37422.1 - 0.15 12.8 0.8 5.1 7.9 0.8 2.6 1 1 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 PhnA_Zn_Ribbon PF08274.12 EKX37422.1 - 0.15 12.0 0.5 0.26 11.3 0.5 1.3 1 0 0 1 1 1 0 PhnA Zinc-Ribbon zinc_ribbon_2 PF13240.6 EKX37422.1 - 0.16 11.8 2.3 1.6 8.5 2.3 2.2 1 1 0 1 1 1 0 zinc-ribbon domain Clathrin PF00637.20 EKX37423.1 - 5.6e-15 55.5 1.0 5.3e-11 42.6 0.2 3.4 4 0 0 4 4 4 2 Region in Clathrin and VPS FGF PF00167.18 EKX37423.1 - 0.014 15.5 0.1 0.029 14.5 0.1 1.5 1 0 0 1 1 1 0 Fibroblast growth factor Kinesin PF00225.23 EKX37424.1 - 8.2e-83 278.1 0.4 3.5e-45 154.4 0.8 2.0 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 EKX37424.1 - 1e-49 168.3 0.0 1.7e-49 167.6 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding TIG PF01833.24 EKX37425.1 - 1.2e-39 134.3 68.5 6.4e-10 39.0 2.2 13.2 12 1 1 13 13 13 12 IPT/TIG domain TIG PF01833.24 EKX37426.1 - 1.3e-36 124.5 110.9 1.6e-05 24.8 0.3 24.6 25 0 0 25 25 25 19 IPT/TIG domain Ribosomal_S3_C PF00189.20 EKX37426.1 - 0.019 15.5 1.3 12 6.4 0.0 3.8 3 0 0 3 3 3 0 Ribosomal protein S3, C-terminal domain RRM_1 PF00076.22 EKX37429.1 - 6.5e-09 35.5 0.0 1.6e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.23 EKX37429.1 - 3e-06 27.0 0.2 1e-05 25.3 0.2 1.9 1 0 0 1 1 1 1 G-patch domain ARS2 PF04959.13 EKX37430.1 - 1.6e-12 48.2 2.1 6.2e-12 46.3 2.1 2.0 1 1 0 1 1 1 1 Arsenite-resistance protein 2 DUF3546 PF12066.8 EKX37430.1 - 4.9e-07 29.9 3.9 1.3e-06 28.6 3.3 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 EKX37430.1 - 0.0013 18.5 0.0 0.0035 17.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) DUF4820 PF16091.5 EKX37430.1 - 6.3 6.1 6.9 3.3 7.0 4.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) cNMP_binding PF00027.29 EKX37431.1 - 0.036 14.1 0.0 0.12 12.4 0.0 2.0 1 1 0 1 1 1 0 Cyclic nucleotide-binding domain Bromodomain PF00439.25 EKX37432.1 - 5.4e-14 52.0 0.0 7.9e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain LRR_8 PF13855.6 EKX37433.1 - 2.1e-10 40.2 3.6 8.6e-09 35.0 0.2 2.6 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 EKX37433.1 - 6.3e-08 32.8 4.1 0.00022 21.6 0.3 3.4 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EKX37433.1 - 0.056 13.5 2.3 8 6.8 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeat P16-Arc PF04699.14 EKX37433.1 - 0.074 13.5 0.4 0.15 12.6 0.2 1.6 2 0 0 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) LRR_1 PF00560.33 EKX37433.1 - 0.47 11.2 4.3 50 5.0 0.1 4.7 5 1 0 5 5 5 0 Leucine Rich Repeat ATP-synt_ab PF00006.25 EKX37434.1 - 2.7e-67 226.5 0.0 3.6e-67 226.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EKX37434.1 - 2.5e-13 50.4 0.5 4.8e-13 49.4 0.5 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain SPRY PF00622.28 EKX37435.1 - 0.037 14.1 2.7 20 5.4 0.1 3.8 3 1 1 4 4 4 0 SPRY domain TPR_17 PF13431.6 EKX37436.1 - 8.4e-26 88.5 10.6 0.00031 20.9 0.2 7.4 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 EKX37436.1 - 1.3e-19 69.1 7.2 0.00079 19.1 0.0 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 EKX37436.1 - 4.7e-17 61.2 0.1 0.17 12.7 0.0 7.1 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX37436.1 - 8.4e-16 56.8 8.0 0.012 15.7 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 EKX37436.1 - 1.1e-14 54.6 3.8 0.054 14.0 0.0 5.8 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 EKX37436.1 - 6.6e-12 45.6 10.4 0.0036 17.5 0.3 5.0 4 2 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX37436.1 - 6.7e-12 44.6 3.3 0.015 15.5 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX37436.1 - 2.6e-11 43.0 8.1 0.0085 15.8 0.4 5.7 6 1 0 6 6 6 2 TPR repeat TPR_7 PF13176.6 EKX37436.1 - 5.8e-11 41.6 2.4 1.5 9.1 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat Coatomer_E PF04733.14 EKX37436.1 - 1.7e-07 30.9 0.7 1.1 8.6 0.1 4.6 1 1 3 5 5 5 2 Coatomer epsilon subunit TPR_10 PF13374.6 EKX37436.1 - 3.5e-07 29.9 6.8 1.6 8.7 0.1 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX37436.1 - 1.9e-06 28.4 1.3 0.59 10.8 0.0 5.2 3 2 1 5 5 5 1 Tetratricopeptide repeat DNA_pol_phi PF04931.13 EKX37436.1 - 2.5e-06 26.0 11.7 3.2e-06 25.6 11.7 1.2 1 0 0 1 1 1 1 DNA polymerase phi DUF2457 PF10446.9 EKX37436.1 - 3.2e-05 23.3 18.8 4.7e-05 22.7 18.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Sel1 PF08238.12 EKX37436.1 - 7.1e-05 23.4 0.2 0.87 10.4 0.0 4.4 5 0 0 5 5 3 1 Sel1 repeat RRN3 PF05327.11 EKX37436.1 - 0.00018 20.2 11.1 0.00026 19.7 11.1 1.2 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 UBN_AB PF14075.6 EKX37436.1 - 0.00048 19.9 6.7 0.00065 19.5 4.6 2.0 2 0 0 2 2 2 1 Ubinuclein conserved middle domain zf-C2H2_4 PF13894.6 EKX37436.1 - 0.0016 19.1 0.5 0.0056 17.4 0.5 2.0 1 0 0 1 1 1 1 C2H2-type zinc finger zf-BED PF02892.15 EKX37436.1 - 0.0024 17.9 0.1 0.049 13.7 0.2 2.6 2 0 0 2 2 2 1 BED zinc finger TPPII_N PF12583.8 EKX37436.1 - 0.0025 18.4 0.6 19 5.8 0.0 4.5 3 1 2 5 5 5 0 Tripeptidyl peptidase II N terminal RNA_pol_3_Rpc31 PF11705.8 EKX37436.1 - 0.0032 17.8 16.3 0.0057 16.9 16.3 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 HTH_5 PF01022.20 EKX37436.1 - 0.0032 17.3 0.1 0.017 14.9 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory protein, arsR family TSNAXIP1_N PF15739.5 EKX37436.1 - 0.0034 17.7 0.4 0.086 13.2 0.0 3.0 3 0 0 3 3 3 1 Translin-associated factor X-interacting N-terminus PigN PF04987.14 EKX37436.1 - 0.0036 16.2 0.0 0.0049 15.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) SDA1 PF05285.12 EKX37436.1 - 0.0054 16.2 7.9 0.0073 15.8 7.9 1.3 1 0 0 1 1 1 1 SDA1 CNDH2_C PF16858.5 EKX37436.1 - 0.0065 16.4 6.5 0.011 15.6 6.5 1.4 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term zf-C2H2 PF00096.26 EKX37436.1 - 0.013 16.0 0.5 0.032 14.7 0.5 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-met PF12874.7 EKX37436.1 - 0.017 15.5 0.2 0.053 13.9 0.2 1.9 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EKX37436.1 - 0.048 14.0 0.2 0.12 12.7 0.2 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Fis1_TPR_C PF14853.6 EKX37436.1 - 0.052 13.6 0.3 20 5.3 0.0 3.1 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat PPP4R2 PF09184.11 EKX37436.1 - 0.063 12.9 9.5 0.094 12.3 9.5 1.3 1 0 0 1 1 1 0 PPP4R2 OrsD PF12013.8 EKX37436.1 - 0.11 12.9 1.5 0.17 12.3 0.3 1.9 2 0 0 2 2 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D NOA36 PF06524.12 EKX37436.1 - 0.12 11.7 23.0 0.32 10.3 23.0 1.8 1 0 0 1 1 1 0 NOA36 protein Dicty_REP PF05086.12 EKX37436.1 - 0.15 10.0 6.9 0.22 9.5 6.9 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TFIIA PF03153.13 EKX37436.1 - 0.17 11.9 12.0 0.28 11.1 12.0 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TRAP_alpha PF03896.16 EKX37436.1 - 0.32 10.2 9.2 0.48 9.6 9.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sporozoite_P67 PF05642.11 EKX37436.1 - 0.43 8.6 5.5 0.59 8.2 5.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 EKX37436.1 - 0.57 8.4 14.6 0.19 10.0 11.5 1.8 2 0 0 2 2 2 0 CDC45-like protein TFB6 PF17110.5 EKX37436.1 - 1.1 8.9 11.3 2.1 8.1 11.3 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Utp14 PF04615.13 EKX37436.1 - 4.2 5.8 9.5 6.2 5.3 9.5 1.2 1 0 0 1 1 1 0 Utp14 protein DUF2076 PF09849.9 EKX37436.1 - 5.4 7.0 16.9 12 5.8 16.9 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) MIT PF04212.18 EKX37436.1 - 6.6 6.9 9.2 1.3e+02 2.8 0.1 5.0 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain FAM176 PF14851.6 EKX37436.1 - 8.7 6.0 12.8 32 4.2 12.9 1.9 1 1 0 1 1 1 0 FAM176 family Med15 PF09606.10 EKX37437.1 - 0.014 14.1 6.2 0.019 13.7 6.2 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spt20 PF12090.8 EKX37437.1 - 0.083 12.5 6.3 0.11 12.1 6.3 1.2 1 0 0 1 1 1 0 Spt20 family PKI PF02827.16 EKX37437.1 - 2.8 8.2 6.7 2.2 8.5 5.0 1.8 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor GTP_EFTU PF00009.27 EKX37438.1 - 5.7e-46 156.5 0.0 8.3e-46 156.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 EKX37438.1 - 2.3e-33 115.4 13.0 3.9e-33 114.6 13.0 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 EKX37438.1 - 1.4e-22 79.8 0.0 3e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EKX37438.1 - 1.2e-21 76.6 0.0 2.4e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EKX37438.1 - 1.4e-11 44.6 0.5 2.9e-11 43.6 0.5 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EKX37438.1 - 8.5e-06 25.8 0.0 2.4e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EKX37438.1 - 0.00016 21.7 0.0 0.0005 20.1 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EKX37438.1 - 0.11 12.4 0.0 0.66 9.9 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Pkinase PF00069.25 EKX37439.1 - 8.6e-75 251.5 0.0 1.1e-74 251.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX37439.1 - 1.5e-42 145.6 0.0 2e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX37439.1 - 1.2e-06 28.1 0.0 0.00026 20.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Seadorna_VP7 PF07387.11 EKX37439.1 - 0.012 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 EKX37439.1 - 0.016 14.0 0.0 0.037 12.8 0.0 1.4 1 1 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EKX37439.1 - 0.037 14.0 0.1 0.15 12.0 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 EKX37439.1 - 0.041 13.5 0.1 0.13 11.9 0.1 1.8 1 1 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 EKX37439.1 - 0.056 12.4 0.0 0.14 11.1 0.0 1.7 1 1 0 1 1 1 0 Haspin like kinase domain DUF2799 PF10973.8 EKX37439.1 - 0.21 12.0 1.1 0.45 11.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2799) PKD_channel PF08016.12 EKX37441.1 - 2.4e-05 23.2 16.2 0.0014 17.4 10.6 2.8 2 1 0 2 2 2 2 Polycystin cation channel DUF4131 PF13567.6 EKX37442.1 - 0.013 15.2 0.2 0.022 14.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Clathrin_H_link PF13838.6 EKX37442.1 - 0.59 10.1 2.5 2 8.4 0.3 2.3 2 0 0 2 2 2 0 Clathrin-H-link Pkinase PF00069.25 EKX37443.1 - 1.2e-21 77.3 0.0 3.4e-20 72.5 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX37443.1 - 3.3e-10 39.7 0.0 1.5e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX37443.1 - 2.7e-06 26.9 0.1 5.3e-06 25.9 0.1 1.4 1 1 0 1 1 1 1 Kinase-like Acetyltransf_CG PF14542.6 EKX37443.1 - 0.28 11.3 0.9 1.2 9.3 0.0 2.4 3 0 0 3 3 3 0 GCN5-related N-acetyl-transferase DUF1281_C PF18406.1 EKX37445.1 - 0.014 15.1 0.6 0.029 14.1 0.6 1.7 1 1 0 1 1 1 0 Ferredoxin-like domain in Api92-like protein EF-hand_7 PF13499.6 EKX37446.1 - 1.5e-33 115.1 21.5 6.7e-11 42.5 0.9 5.3 5 1 0 5 5 5 3 EF-hand domain pair EF-hand_1 PF00036.32 EKX37446.1 - 6.5e-30 100.4 24.4 1.7e-05 24.0 1.4 7.2 7 0 0 7 7 7 6 EF hand EF-hand_6 PF13405.6 EKX37446.1 - 6.3e-29 97.4 21.8 4.6e-06 26.1 0.0 7.4 8 0 0 8 8 8 6 EF-hand domain EF-hand_5 PF13202.6 EKX37446.1 - 2.6e-28 96.3 20.3 2.6e-06 26.6 0.0 6.2 6 0 0 6 6 6 5 EF hand EF-hand_8 PF13833.6 EKX37446.1 - 1.8e-19 69.3 25.3 1.1e-05 25.2 1.8 6.8 4 2 3 7 7 7 6 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX37446.1 - 2.7e-15 56.7 4.8 2.7e-06 27.7 0.2 3.9 2 2 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EKX37446.1 - 1.3e-07 31.5 5.0 0.034 14.1 0.1 4.3 3 1 1 4 4 4 3 Cytoskeletal-regulatory complex EF hand TP53IP5 PF15331.6 EKX37446.1 - 0.0048 17.1 1.6 0.01 16.0 1.6 1.5 1 0 0 1 1 1 1 Cellular tumour antigen p53-inducible 5 EF-hand_13 PF17958.1 EKX37446.1 - 0.0061 16.3 0.0 7.3 6.5 0.0 3.4 3 0 0 3 3 2 2 EF-hand domain Caleosin PF05042.13 EKX37446.1 - 0.0086 16.0 5.0 6.3 6.7 0.0 5.1 5 1 3 8 8 7 1 Caleosin related protein EF-hand_11 PF08976.11 EKX37446.1 - 0.013 16.4 0.2 0.42 11.5 0.0 3.0 4 0 0 4 4 3 0 EF-hand domain AAA_34 PF13872.6 EKX37446.1 - 0.016 14.1 0.4 11 4.8 0.0 3.3 3 1 0 3 3 3 0 P-loop containing NTP hydrolase pore-1 Dimerisation PF08100.11 EKX37446.1 - 0.085 12.9 0.0 3.6 7.7 0.0 3.5 3 1 1 4 4 4 0 Dimerisation domain DUF3322 PF11795.8 EKX37446.1 - 0.11 12.6 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) EF-hand_14 PF17959.1 EKX37446.1 - 0.14 12.5 0.7 5.6 7.4 0.0 3.8 3 1 1 4 4 4 0 EF-hand domain THEG PF14912.6 EKX37446.1 - 1.9 9.0 5.1 2.5 8.6 2.4 2.2 1 1 1 2 2 2 0 Testicular haploid expressed repeat Dockerin_1 PF00404.18 EKX37446.1 - 3.1 8.1 6.9 26 5.1 0.5 4.2 3 2 0 3 3 3 0 Dockerin type I domain EF-hand_7 PF13499.6 EKX37447.1 - 1.5e-25 89.5 21.6 1.6e-10 41.3 2.9 5.8 4 1 0 5 5 5 3 EF-hand domain pair EF-hand_1 PF00036.32 EKX37447.1 - 9.3e-24 81.2 24.5 1.3e-06 27.5 0.5 6.5 7 0 0 7 7 7 5 EF hand EF-hand_6 PF13405.6 EKX37447.1 - 5.1e-19 66.5 22.7 0.00023 20.9 0.1 7.3 8 0 0 8 8 8 5 EF-hand domain EF-hand_5 PF13202.6 EKX37447.1 - 6.3e-19 66.6 17.4 1.1e-05 24.7 0.4 5.2 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 EKX37447.1 - 8.1e-19 67.2 22.0 1.1e-06 28.3 0.2 5.8 3 2 3 6 6 6 5 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX37447.1 - 1.8e-09 37.9 6.4 4.4e-06 27.0 0.0 3.6 3 1 1 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EKX37447.1 - 6.7e-09 35.6 7.1 0.033 14.1 0.1 4.7 3 1 2 5 5 5 3 Cytoskeletal-regulatory complex EF hand EF-hand_13 PF17958.1 EKX37447.1 - 0.011 15.5 0.0 6.7 6.6 0.0 3.0 2 0 0 2 2 2 0 EF-hand domain Caleosin PF05042.13 EKX37447.1 - 0.027 14.4 0.2 8 6.4 0.0 4.1 3 1 2 5 5 5 0 Caleosin related protein PfUIS3 PF11567.8 EKX37447.1 - 0.1 13.0 0.1 2.7 8.4 0.0 2.5 2 0 0 2 2 2 0 Plasmodium falciparum UIS3 membrane protein TcpS PF17456.2 EKX37447.1 - 1.9 8.5 5.2 17 5.5 0.5 2.9 2 0 0 2 2 2 0 Toxin-coregulated pilus protein S Sigma70_r1_1 PF03979.14 EKX37447.1 - 3.3 7.8 10.2 3.8 7.6 0.0 4.0 4 0 0 4 4 4 0 Sigma-70 factor, region 1.1 Ank_2 PF12796.7 EKX37448.1 - 1.2e-19 70.7 0.3 4.3e-14 52.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX37448.1 - 1.3e-14 54.4 3.2 4.5e-06 27.1 0.1 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX37448.1 - 1.6e-10 41.1 0.3 1.7e-05 25.0 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX37448.1 - 2.1e-10 40.6 2.7 0.00099 19.5 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EKX37448.1 - 1.4e-08 34.3 0.5 0.035 14.6 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat MauJ PF17419.2 EKX37448.1 - 0.099 12.1 0.0 0.11 11.9 0.0 1.0 1 0 0 1 1 1 0 Methylamine utilization protein MauJ SPRY PF00622.28 EKX37449.1 - 1.8e-08 34.5 0.1 4.9e-08 33.1 0.1 1.7 1 0 0 1 1 1 1 SPRY domain Arm PF00514.23 EKX37450.1 - 0 2021.0 241.7 2.1e-11 43.4 0.0 78.0 77 1 1 78 78 78 75 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EKX37450.1 - 2e-120 392.2 170.5 1.4e-05 25.5 0.1 54.4 39 16 22 61 61 61 34 HEAT-like repeat Arm_2 PF04826.13 EKX37450.1 - 1.2e-96 323.1 133.8 5.4e-12 45.7 0.4 31.7 3 3 24 31 31 31 28 Armadillo-like HEAT_2 PF13646.6 EKX37450.1 - 3.8e-90 296.4 129.9 0.00013 22.3 0.2 35.1 10 8 28 43 43 43 36 HEAT repeats KAP PF05804.12 EKX37450.1 - 2.6e-84 283.7 20.0 1.4e-07 30.1 0.3 21.0 2 2 17 22 22 22 20 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 EKX37450.1 - 2.4e-49 168.4 36.7 1.9e-07 30.7 0.3 20.6 4 3 10 15 15 15 10 V-ATPase subunit H Cnd1 PF12717.7 EKX37450.1 - 1.4e-39 135.7 66.0 0.24 11.5 0.9 27.1 8 6 13 27 27 27 14 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EKX37450.1 - 4.6e-38 126.0 140.7 0.38 11.1 0.0 49.7 53 0 0 53 53 51 6 HEAT repeat Atx10homo_assoc PF09759.9 EKX37450.1 - 1.3e-20 73.2 88.4 1 9.4 0.1 33.3 20 9 24 44 44 43 4 Spinocerebellar ataxia type 10 protein domain DUF3361 PF11841.8 EKX37450.1 - 6.7e-16 58.6 102.2 0.00084 19.3 0.2 26.1 9 6 12 29 29 29 4 Domain of unknown function (DUF3361) DUF5578 PF17741.1 EKX37450.1 - 2.7e-15 56.5 90.8 0.051 13.0 0.2 23.4 7 6 17 26 26 26 7 Family of unknown function (DUF5578) CLASP_N PF12348.8 EKX37450.1 - 1e-14 54.7 29.8 0.18 11.3 0.8 15.9 15 4 3 18 18 18 4 CLASP N terminal UNC45-central PF11701.8 EKX37450.1 - 2.1e-14 53.7 31.4 0.28 11.1 0.0 18.6 20 2 3 23 23 22 2 Myosin-binding striated muscle assembly central CTNNBL PF08216.11 EKX37450.1 - 0.00012 22.2 25.5 4.5 7.5 0.0 16.2 20 2 2 22 22 19 1 Catenin-beta-like, Arm-motif containing nuclear Tti2 PF10521.9 EKX37450.1 - 0.0003 20.4 7.4 47 3.4 0.0 9.5 10 1 0 11 11 11 0 Tti2 family RTP1_C1 PF10363.9 EKX37450.1 - 0.028 14.6 61.0 4.8 7.4 0.0 19.3 19 3 4 23 23 22 0 Required for nuclear transport of RNA pol II C-terminus 1 Nipped-B_C PF12830.7 EKX37450.1 - 0.079 12.9 25.9 28 4.6 0.0 13.4 16 2 2 18 18 17 0 Sister chromatid cohesion C-terminus Tex_N PF09371.10 EKX37450.1 - 0.098 12.3 2.4 34 4.1 0.0 5.5 7 0 0 7 7 6 0 Tex-like protein N-terminal domain Chaperone_III PF07824.12 EKX37450.1 - 0.17 12.2 5.4 5.8 7.2 0.1 6.1 7 0 0 7 7 4 0 Type III secretion chaperone domain CO_dh PF02552.16 EKX37450.1 - 0.22 11.3 0.6 59 3.4 0.0 5.6 7 0 0 7 7 5 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit NopRA1 PF16201.5 EKX37450.1 - 1 8.9 33.8 4.7 6.7 0.0 14.5 15 2 3 18 18 17 0 Nucleolar pre-ribosomal-associated protein 1 HMD PF03201.16 EKX37450.1 - 2.9 8.2 5.9 19 5.6 0.4 5.3 5 2 1 6 6 6 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Mito_carr PF00153.27 EKX37452.1 - 3.2e-50 168.0 2.7 4.4e-18 65.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein KH_1 PF00013.29 EKX37453.1 - 0.0003 20.6 0.2 0.00059 19.6 0.2 1.5 1 0 0 1 1 1 1 KH domain zf-RING_2 PF13639.6 EKX37454.1 - 0.0081 16.5 6.9 0.013 15.8 6.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EKX37454.1 - 0.97 9.4 5.6 8.5 6.3 5.6 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Methyltransf_32 PF13679.6 EKX37455.1 - 1e-07 32.0 1.4 1.4e-06 28.4 1.4 2.3 1 1 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 EKX37455.1 - 0.00059 19.2 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G MTS PF05175.14 EKX37455.1 - 0.1 12.1 0.1 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Myb_DNA-binding PF00249.31 EKX37456.1 - 1.7e-08 34.5 0.1 5.3e-08 32.9 0.1 1.8 1 1 0 1 1 1 1 Myb-like DNA-binding domain TEA PF01285.18 EKX37456.1 - 0.11 12.5 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 TEA/ATTS domain SRP-alpha_N PF04086.13 EKX37456.1 - 2.8 7.8 6.7 4.4 7.1 6.7 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal AAA_33 PF13671.6 EKX37457.1 - 2.2e-06 27.9 0.0 7.1e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EKX37457.1 - 6.2e-05 23.6 0.1 0.00034 21.1 0.0 2.1 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EKX37457.1 - 0.00063 19.1 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.6 EKX37457.1 - 0.0013 19.0 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EKX37457.1 - 0.0019 18.6 0.0 0.02 15.3 0.0 2.0 1 1 1 2 2 2 1 AAA domain APS_kinase PF01583.20 EKX37457.1 - 0.003 17.5 0.0 0.0056 16.6 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase CoaE PF01121.20 EKX37457.1 - 0.0034 17.1 0.1 1.9 8.1 0.0 2.3 2 0 0 2 2 2 2 Dephospho-CoA kinase AAA_16 PF13191.6 EKX37457.1 - 0.0058 17.0 0.3 0.013 15.9 0.2 1.7 2 1 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 EKX37457.1 - 0.0092 15.9 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 EKX37457.1 - 0.032 14.6 0.1 0.056 13.9 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EKX37457.1 - 0.034 14.5 0.1 0.16 12.4 0.1 2.1 1 1 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 EKX37457.1 - 0.048 13.2 0.0 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 EKX37457.1 - 0.06 13.1 0.1 0.1 12.3 0.0 1.5 2 0 0 2 2 2 0 Cytidylate kinase RsgA_GTPase PF03193.16 EKX37457.1 - 0.075 12.9 0.1 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 EKX37457.1 - 0.093 13.2 1.0 0.13 12.8 1.0 1.8 1 1 0 1 1 1 0 ABC transporter TsaE PF02367.17 EKX37457.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CbiA PF01656.23 EKX37457.1 - 0.16 12.0 0.2 0.76 9.8 0.2 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PRK PF00485.18 EKX37457.1 - 0.17 11.6 0.8 0.36 10.6 0.4 2.0 1 1 1 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.6 EKX37457.1 - 0.21 11.4 0.2 0.41 10.4 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain HD_2 PF12917.7 EKX37458.1 - 0.049 13.4 1.7 0.056 13.2 0.5 1.7 2 0 0 2 2 2 0 HD containing hydrolase-like enzyme GnRH PF00446.17 EKX37458.1 - 0.13 12.6 0.7 0.26 11.7 0.7 1.5 1 0 0 1 1 1 0 Gonadotropin-releasing hormone YiiD_C PF09500.10 EKX37459.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) CUB PF00431.20 EKX37460.1 - 5.6e-08 33.1 0.0 2.9e-07 30.8 0.0 2.4 1 0 0 1 1 1 1 CUB domain GLEYA PF10528.9 EKX37460.1 - 8.9e-07 29.2 2.6 2.7e-06 27.7 0.9 2.9 2 0 0 2 2 2 1 GLEYA domain PA14 PF07691.12 EKX37460.1 - 1.7e-05 24.7 0.3 0.00015 21.6 0.9 2.2 2 0 0 2 2 2 1 PA14 domain MbtH PF03621.13 EKX37460.1 - 0.00039 19.8 12.2 34 4.0 0.0 8.3 9 0 0 9 9 9 3 MbtH-like protein Ank_2 PF12796.7 EKX37464.1 - 0.0014 19.2 0.0 0.0086 16.6 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) CompInhib_SCIN PF11546.8 EKX37465.1 - 0.038 14.0 0.1 7.3 6.7 0.0 2.2 2 0 0 2 2 2 0 Staphylococcal complement inhibitor SCIN Hexokinase_2 PF03727.16 EKX37466.1 - 1e-53 182.3 0.1 3.8e-52 177.1 0.0 2.5 2 1 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.21 EKX37466.1 - 7.8e-44 150.0 0.1 1.2e-43 149.4 0.1 1.2 1 0 0 1 1 1 1 Hexokinase RWP-RK PF02042.15 EKX37468.1 - 1.3e-22 79.5 0.1 1.9e-22 78.9 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_6 PF01418.17 EKX37468.1 - 0.13 12.3 0.0 0.34 10.9 0.0 1.7 2 1 0 2 2 2 0 Helix-turn-helix domain, rpiR family Cnd2 PF05786.14 EKX37470.1 - 6.7e-95 319.4 10.8 8e-49 167.0 3.6 3.4 2 2 1 3 3 3 3 Condensin complex subunit 2 CNDH2_N PF06278.11 EKX37470.1 - 0.00073 19.7 0.1 0.002 18.3 0.1 1.7 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal TLP-20 PF06088.11 EKX37470.1 - 2.6 7.9 4.4 6.4 6.6 0.7 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF3408 PF11888.8 EKX37472.1 - 0.01 16.0 3.9 0.016 15.4 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) AAA_23 PF13476.6 EKX37472.1 - 0.015 15.8 7.4 0.14 12.6 5.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EKX37472.1 - 0.016 15.8 0.3 0.016 15.8 0.3 2.3 2 0 0 2 2 2 0 AAA domain Sporozoite_P67 PF05642.11 EKX37472.1 - 0.022 12.9 2.8 0.032 12.3 2.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2722 PF10846.8 EKX37472.1 - 0.057 12.4 4.6 0.069 12.1 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RsgA_GTPase PF03193.16 EKX37472.1 - 0.076 12.9 1.7 0.16 11.9 1.7 1.6 1 1 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 EKX37472.1 - 0.11 12.8 0.2 0.11 12.8 0.2 3.0 2 1 0 2 2 1 0 AAA domain DDHD PF02862.17 EKX37472.1 - 0.14 12.3 1.1 0.16 12.1 1.1 1.1 1 0 0 1 1 1 0 DDHD domain AAA_16 PF13191.6 EKX37472.1 - 0.24 11.8 0.1 0.24 11.8 0.1 2.3 1 1 1 2 2 2 0 AAA ATPase domain Presenilin PF01080.17 EKX37472.1 - 0.24 10.1 3.8 0.25 10.1 3.8 1.1 1 0 0 1 1 1 0 Presenilin TERB2 PF15101.6 EKX37472.1 - 0.55 10.2 5.9 0.76 9.8 5.9 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Connexin PF00029.19 EKX37472.1 - 0.92 9.2 2.6 1.2 8.8 2.6 1.2 1 0 0 1 1 1 0 Connexin EIIBC-GUT_N PF03612.14 EKX37472.1 - 0.96 9.2 5.6 1.6 8.4 5.6 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus RR_TM4-6 PF06459.12 EKX37472.1 - 1.6 8.5 9.6 2 8.2 9.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NOA36 PF06524.12 EKX37472.1 - 1.8 7.8 6.0 2.8 7.2 6.0 1.3 1 0 0 1 1 1 0 NOA36 protein Spt20 PF12090.8 EKX37472.1 - 2 8.0 10.0 2.8 7.5 10.0 1.1 1 0 0 1 1 1 0 Spt20 family Paf1 PF03985.13 EKX37472.1 - 2.7 6.9 16.3 3.9 6.4 16.3 1.2 1 0 0 1 1 1 0 Paf1 U1snRNP70_N PF12220.8 EKX37472.1 - 3.2 8.5 10.1 6.1 7.5 10.1 1.4 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Hid1 PF12722.7 EKX37472.1 - 3.3 5.7 4.4 3.7 5.6 4.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MRP-S27 PF10037.9 EKX37472.1 - 4.2 6.1 9.4 5.4 5.8 9.4 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF3915 PF13054.6 EKX37472.1 - 4.5 7.3 6.9 10 6.1 6.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.15 EKX37472.1 - 5 5.3 16.3 6.5 4.9 16.3 1.1 1 0 0 1 1 1 0 Atrophin-1 family Nop14 PF04147.12 EKX37472.1 - 5 5.2 16.3 5.9 5.0 16.3 1.1 1 0 0 1 1 1 0 Nop14-like family Roughex PF06020.11 EKX37472.1 - 7.1 5.6 12.8 11 5.1 12.8 1.3 1 0 0 1 1 1 0 Drosophila roughex protein AAA_33 PF13671.6 EKX37472.1 - 8 6.6 8.2 0.54 10.4 0.4 2.4 2 1 0 2 2 2 0 AAA domain Tmemb_9 PF05434.11 EKX37473.1 - 0.017 15.0 4.2 0.017 15.0 4.2 2.3 1 1 1 2 2 2 0 TMEM9 DUF2207 PF09972.9 EKX37473.1 - 0.08 11.7 5.6 0.11 11.3 5.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Shisa PF13908.6 EKX37473.1 - 0.088 13.1 4.2 4.2 7.6 4.2 2.1 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator FA_desaturase PF00487.24 EKX37473.1 - 0.12 12.1 2.8 0.19 11.5 2.8 1.4 1 0 0 1 1 1 0 Fatty acid desaturase Anoctamin PF04547.12 EKX37473.1 - 0.21 10.4 5.2 0.37 9.6 5.2 1.4 1 0 0 1 1 1 0 Calcium-activated chloride channel YfhO PF09586.10 EKX37473.1 - 8.7 4.4 8.0 11 4.1 8.0 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO JSRP PF15312.6 EKX37475.1 - 8.8e-10 38.4 12.0 15 5.6 0.0 8.0 7 0 0 7 7 7 6 Junctional sarcoplasmic reticulum protein 40S_S4_C PF16121.5 EKX37475.1 - 2.2e-09 36.8 0.0 25 4.6 0.0 6.7 6 0 0 6 6 6 0 40S ribosomal protein S4 C-terminus RnlA_toxin PF15935.5 EKX37475.1 - 2e-06 27.8 0.9 1.1e+02 2.5 0.0 7.0 7 0 0 7 7 7 0 RNase LS, bacterial toxin MEA1 PF06910.11 EKX37475.1 - 4.5e-06 27.3 6.0 76 3.9 0.0 6.3 6 0 0 6 6 6 0 Male enhanced antigen 1 (MEA1) OCC1 PF15506.6 EKX37475.1 - 0.00054 20.0 10.7 90 3.3 0.0 6.6 7 0 0 7 7 7 0 OCC1 family DUF2894 PF11445.8 EKX37475.1 - 0.07 13.6 73.0 8.1 6.9 1.1 9.8 1 1 7 8 8 8 0 Protein of unknown function (DUF2894) DNA_pol3_gamma3 PF12169.8 EKX37475.1 - 0.19 11.6 30.7 14 5.6 0.3 7.0 6 1 1 7 7 7 0 DNA polymerase III subunits gamma and tau domain III Apolipoprotein PF01442.18 EKX37475.1 - 0.33 10.8 125.9 0.57 10.0 10.0 8.4 9 0 0 9 9 9 0 Apolipoprotein A1/A4/E domain T7SS_ESX_EspC PF10824.8 EKX37475.1 - 5.6 7.5 35.5 56 4.3 0.6 8.1 7 0 0 7 7 7 0 Excreted virulence factor EspC, type VII ESX diderm Peptidase_S51 PF03575.17 EKX37476.1 - 0.098 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 LysM PF01476.20 EKX37477.1 - 0.022 14.8 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 LysM domain EptA_B_N PF08019.12 EKX37477.1 - 0.18 11.7 3.0 0.3 11.0 3.0 1.2 1 0 0 1 1 1 0 Phosphoethanolamine transferase EptA/EptB Aerolysin PF01117.20 EKX37478.1 - 0.1 11.8 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Aerolysin toxin Tmem26 PF09772.9 EKX37478.1 - 0.15 11.3 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 26 TTL PF03133.15 EKX37479.1 - 3.3e-31 108.5 0.0 4.1e-20 72.1 0.0 3.1 1 1 1 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EKX37479.1 - 8.7e-11 41.6 0.0 5.6e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EKX37479.1 - 2.9e-05 23.5 0.0 0.16 11.2 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp DUF3446 PF11928.8 EKX37480.1 - 1.4 9.3 17.2 0.34 11.3 12.9 2.2 2 0 0 2 2 2 0 Early growth response N-terminal domain SR-25 PF10500.9 EKX37480.1 - 2.5 7.6 16.3 4.6 6.8 16.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein JHY PF15261.6 EKX37483.1 - 9.5e-10 39.3 0.5 9.5e-10 39.3 0.5 1.8 2 0 0 2 2 2 1 Jhy protein RPAP2_Rtr1 PF04181.13 EKX37488.1 - 1.2e-14 54.3 0.5 2.1e-14 53.6 0.1 1.7 2 0 0 2 2 2 1 Rtr1/RPAP2 family Phage_term_smal PF05944.12 EKX37488.1 - 0.15 12.1 0.3 0.23 11.4 0.3 1.3 1 0 0 1 1 1 0 Phage small terminase subunit Rad50_zn_hook PF04423.14 EKX37488.1 - 0.88 9.5 5.7 4.9 7.1 0.6 3.0 3 0 0 3 3 3 0 Rad50 zinc hook motif Pkinase PF00069.25 EKX37489.1 - 4.2e-71 239.4 0.0 5.1e-71 239.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX37489.1 - 6.5e-35 120.7 0.0 8.5e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX37489.1 - 1e-07 31.6 0.0 1.8e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EKX37489.1 - 2.3e-06 26.6 0.0 3.1e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EKX37489.1 - 0.0025 17.2 0.1 0.0036 16.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EKX37489.1 - 0.058 13.0 0.0 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EKX37489.1 - 0.073 12.7 0.2 0.13 11.9 0.2 1.4 1 1 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 EKX37489.1 - 0.077 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 EKX37489.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase PF00069.25 EKX37491.1 - 5.2e-66 222.7 0.0 6.5e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX37491.1 - 9.9e-35 120.1 0.0 3e-34 118.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EKX37491.1 - 8.3e-05 21.7 0.0 0.00013 21.0 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EKX37491.1 - 0.00055 19.3 0.0 0.00083 18.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX37491.1 - 0.0036 17.3 0.1 0.01 15.8 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EKX37491.1 - 0.0081 15.5 0.0 0.046 13.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EKX37491.1 - 0.16 10.7 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FmdA_AmdA PF03069.15 EKX37494.1 - 3.8e-170 565.7 0.0 4.3e-170 565.5 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family PDZ PF00595.24 EKX37496.1 - 3.9e-19 68.8 0.1 3.7e-08 33.6 0.0 2.2 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EKX37496.1 - 9.4e-19 67.0 0.2 3.3e-08 33.3 0.1 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX37496.1 - 2.6e-13 50.1 0.0 5.3e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 EKX37496.1 - 0.00075 19.4 0.0 0.053 13.5 0.0 2.9 3 0 0 3 3 3 1 Tricorn protease PDZ domain PDZ_4 PF17816.1 EKX37496.1 - 0.1 13.0 0.0 0.67 10.4 0.0 2.1 2 0 0 2 2 2 0 PDZ domain DSPn PF14671.6 EKX37500.1 - 5.3e-27 95.0 0.0 1.3e-26 93.7 0.0 1.7 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EKX37500.1 - 2.8e-06 27.2 0.0 4.4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Glyco_hydro_20 PF00728.22 EKX37501.1 - 6.1e-77 259.4 0.0 2.5e-75 254.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EKX37501.1 - 2.1e-10 41.4 0.0 4e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like VCPO_N PF17897.1 EKX37501.1 - 0.17 11.7 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 Vanadium chloroperoxidase N-terminal domain EF-hand_1 PF00036.32 EKX37503.1 - 2.3e-17 61.2 6.2 6.9e-05 22.1 0.2 3.8 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 EKX37503.1 - 4.7e-17 62.2 6.1 9.7e-12 45.2 0.9 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX37503.1 - 1.3e-13 49.7 5.3 3.7e-05 23.3 0.2 3.8 3 1 1 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 EKX37503.1 - 1.7e-13 50.2 3.8 1.4e-09 37.6 0.5 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EKX37503.1 - 1.3e-11 43.5 3.8 0.00048 19.5 0.2 3.3 3 0 0 3 3 3 3 EF hand SPARC_Ca_bdg PF10591.9 EKX37503.1 - 0.02 15.2 3.4 2.9 8.2 1.8 3.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region SurA_N_3 PF13624.6 EKX37503.1 - 0.081 12.7 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 SurA N-terminal domain Bac_DNA_binding PF00216.21 EKX37503.1 - 0.11 12.7 0.0 0.45 10.8 0.0 2.0 1 1 1 2 2 2 0 Bacterial DNA-binding protein EF-hand_4 PF12763.7 EKX37503.1 - 0.34 10.9 4.2 4.2 7.4 0.1 2.8 1 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Ammonium_transp PF00909.21 EKX37504.1 - 7.8e-116 387.0 32.4 9.9e-116 386.7 32.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family THOC7 PF05615.13 EKX37505.1 - 0.014 15.7 11.6 0.014 15.7 11.6 2.9 2 1 0 2 2 2 0 Tho complex subunit 7 DUF5618 PF18498.1 EKX37505.1 - 0.038 14.2 8.7 0.084 13.1 0.5 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF5618) RIC3 PF15361.6 EKX37505.1 - 0.078 13.4 0.2 0.078 13.4 0.2 3.4 2 1 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 UPF0242 PF06785.11 EKX37505.1 - 0.1 12.7 43.2 1.8 8.6 21.5 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 EKX37505.1 - 0.34 10.2 17.9 0.5 9.7 17.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) KIAA1430 PF13879.6 EKX37505.1 - 0.67 10.7 35.1 0.72 10.6 12.8 3.9 2 2 1 3 3 3 0 KIAA1430 homologue Conotoxin PF02950.17 EKX37505.1 - 2 9.5 0.1 2 9.5 0.1 3.5 3 2 0 3 3 3 0 Conotoxin DUF1664 PF07889.12 EKX37505.1 - 2.5 8.2 19.2 0.61 10.1 6.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) PLAT PF01477.23 EKX37506.1 - 4.8e-12 46.5 0.1 8.7e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 PLAT/LH2 domain ABC_tran_CTD PF16326.5 EKX37506.1 - 0.09 13.0 1.8 0.13 12.5 0.4 1.9 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF3293 PF11697.8 EKX37506.1 - 0.13 12.7 0.0 0.4 11.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3293) SOGA PF11365.8 EKX37506.1 - 3 9.1 8.0 9.6 7.4 0.7 2.8 2 1 1 3 3 3 0 Protein SOGA DUF1768 PF08719.11 EKX37507.1 - 2e-13 50.9 0.3 1.5e-11 44.8 0.1 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF1768) OTU PF02338.19 EKX37507.1 - 2.3e-08 34.6 0.1 6.1e-08 33.2 0.1 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease MSG PF02349.15 EKX37507.1 - 2.5 8.4 7.5 0.87 9.8 4.2 1.9 2 0 0 2 2 2 0 Major surface glycoprotein TPR_12 PF13424.6 EKX37508.1 - 0.00027 21.2 0.1 0.12 12.6 0.0 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX37508.1 - 0.0028 17.6 2.5 1.5 9.1 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX37508.1 - 0.004 17.1 0.0 0.97 9.6 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Glyco_trans_1_4 PF13692.6 EKX37508.1 - 0.15 12.5 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 RTX_C PF08339.10 EKX37508.1 - 2.8 8.0 9.1 0.65 10.0 1.1 2.3 2 0 0 2 2 2 0 RTX C-terminal domain zf-CCHC_5 PF14787.6 EKX37509.1 - 0.17 11.6 0.2 0.97 9.2 0.1 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger TP_methylase PF00590.20 EKX37511.1 - 1.7e-17 64.1 0.0 1.9e-17 64.0 0.0 1.0 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases OrfB_Zn_ribbon PF07282.11 EKX37511.1 - 0.0075 16.2 0.0 0.023 14.6 0.0 1.8 2 0 0 2 2 2 1 Putative transposase DNA-binding domain Terminase_1 PF03354.15 EKX37511.1 - 0.13 10.8 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Phage Terminase Glyco_transf_90 PF05686.12 EKX37512.1 - 3.7e-22 78.8 0.1 4.6e-22 78.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 EKX37512.1 - 0.11 12.9 0.0 0.31 11.5 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferases group 1 LSM PF01423.22 EKX37514.1 - 0.076 12.7 0.4 0.33 10.7 0.1 2.1 2 1 0 2 2 2 0 LSM domain Methyltransf_23 PF13489.6 EKX37517.1 - 3.8e-15 56.1 0.0 8e-15 55.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX37517.1 - 2.9e-14 53.5 0.2 6.5e-14 52.4 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX37517.1 - 9.8e-14 51.8 0.1 2.1e-13 50.7 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX37517.1 - 1.8e-12 47.3 0.1 7.1e-12 45.4 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX37517.1 - 1.6e-09 38.4 0.0 3.4e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EKX37517.1 - 1e-07 31.6 0.1 1.7e-07 30.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 EKX37517.1 - 9e-06 25.8 0.0 1.4e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX37517.1 - 2e-05 24.1 0.1 3e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 EKX37517.1 - 4.4e-05 22.6 0.0 6.2e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.19 EKX37517.1 - 0.00014 21.7 0.1 0.0002 21.2 0.1 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 EKX37517.1 - 0.00023 20.6 0.0 0.00037 19.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 EKX37517.1 - 0.00076 19.1 0.0 0.0015 18.2 0.0 1.4 1 1 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 EKX37517.1 - 0.0033 17.0 0.2 0.0061 16.1 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Pox_MCEL PF03291.16 EKX37517.1 - 0.0035 16.5 0.3 0.17 10.9 0.0 2.1 1 1 1 2 2 2 1 mRNA capping enzyme Methyltransf_18 PF12847.7 EKX37517.1 - 0.0037 17.2 0.0 0.0057 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EKX37517.1 - 0.011 15.2 0.1 0.019 14.3 0.1 1.6 1 1 0 1 1 1 0 Tellurite resistance protein TehB FtsJ PF01728.19 EKX37517.1 - 0.016 15.3 0.2 0.1 12.7 0.2 2.0 1 1 0 1 1 1 0 FtsJ-like methyltransferase TPMT PF05724.11 EKX37517.1 - 0.024 14.3 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MetW PF07021.12 EKX37517.1 - 0.025 14.2 0.1 0.043 13.4 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DREV PF05219.12 EKX37517.1 - 0.027 13.6 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase N6_N4_Mtase PF01555.18 EKX37517.1 - 0.039 13.7 0.1 0.38 10.4 0.1 2.0 2 0 0 2 2 2 0 DNA methylase NNMT_PNMT_TEMT PF01234.17 EKX37517.1 - 0.13 11.4 0.1 0.7 9.0 0.1 2.2 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family zf-CCHC_5 PF14787.6 EKX37518.1 - 0.12 12.1 0.2 0.61 9.8 0.1 2.1 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Glyco_transf_90 PF05686.12 EKX37519.1 - 1.6e-15 56.9 0.2 1.6e-15 56.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 EKX37519.1 - 0.033 14.6 0.0 0.042 14.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferases group 1 TP_methylase PF00590.20 EKX37520.1 - 6.5e-21 75.2 0.0 1.9e-20 73.7 0.0 1.6 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TIG PF01833.24 EKX37521.1 - 6.3e-57 189.6 31.2 8.9e-09 35.3 0.0 10.0 9 1 0 9 9 9 9 IPT/TIG domain Ank_4 PF13637.6 EKX37521.1 - 2.5e-08 34.3 0.0 6.5e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX37521.1 - 7.4e-07 29.4 0.4 0.00061 20.1 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EKX37521.1 - 7.6e-07 29.3 0.2 3.7e-05 23.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX37521.1 - 6.3e-06 26.7 0.0 1.7e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) fn2 PF00040.19 EKX37521.1 - 1.2e-05 25.5 3.8 1.2e-05 25.5 3.8 2.4 2 0 0 2 2 2 1 Fibronectin type II domain Ank_3 PF13606.6 EKX37521.1 - 0.0082 16.6 0.1 0.48 11.1 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat SCAB-ABD PF16711.5 EKX37521.1 - 0.097 12.6 2.4 0.24 11.3 0.2 2.3 2 0 0 2 2 2 0 Actin-binding domain of plant-specific actin-binding protein DNA_pol_phi PF04931.13 EKX37521.1 - 1.6 6.7 15.7 2.2 6.2 15.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pepsin-I3 PF06394.13 EKX37522.1 - 2.3 8.4 5.3 13 6.1 0.4 3.0 2 1 1 3 3 3 0 Pepsin inhibitor-3-like repeated domain T2SS_PulS_OutS PF09691.10 EKX37524.1 - 0.033 14.4 0.3 0.038 14.2 0.3 1.2 1 0 0 1 1 1 0 Type II secretion system pilotin lipoprotein (PulS_OutS) DUF483 PF04467.12 EKX37526.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF483) Laminin_I PF06008.14 EKX37527.1 - 0.00023 20.9 22.8 0.00047 19.9 9.1 3.1 3 0 0 3 3 3 2 Laminin Domain I MAAL_N PF05034.13 EKX37527.1 - 0.002 17.8 1.9 2.6 7.7 0.1 3.0 2 1 1 3 3 3 2 Methylaspartate ammonia-lyase N-terminus Novirhabdo_Nv PF05554.11 EKX37527.1 - 0.0043 16.8 0.3 3.2 7.5 0.0 2.3 2 0 0 2 2 2 2 Viral hemorrhagic septicemia virus non-virion protein WXG100 PF06013.12 EKX37527.1 - 0.038 14.2 13.0 2.2 8.6 0.3 4.5 3 2 1 4 4 4 0 Proteins of 100 residues with WXG Glyco_transf_15 PF01793.16 EKX37527.1 - 0.044 13.0 0.4 5.2 6.2 0.0 2.6 2 2 0 2 2 2 0 Glycolipid 2-alpha-mannosyltransferase FliG_M PF14841.6 EKX37527.1 - 0.046 14.0 2.4 0.85 9.9 0.1 3.4 2 2 2 4 4 4 0 FliG middle domain Synaptobrevin PF00957.21 EKX37527.1 - 0.06 13.1 19.2 1.8 8.4 1.7 4.2 3 1 1 4 4 4 0 Synaptobrevin SesA PF17107.5 EKX37527.1 - 0.11 12.6 3.6 10 6.4 0.1 2.8 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF948 PF06103.11 EKX37527.1 - 0.23 11.7 11.8 0.17 12.2 2.3 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF802 PF05650.11 EKX37527.1 - 0.24 11.9 1.6 34 5.0 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF802) Laminin_II PF06009.12 EKX37527.1 - 0.26 11.3 14.3 2.1 8.4 0.9 2.8 1 1 1 2 2 2 0 Laminin Domain II Fib_alpha PF08702.10 EKX37527.1 - 0.42 10.8 22.5 1.1 9.4 8.8 3.1 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Spore_III_AB PF09548.10 EKX37527.1 - 0.49 10.5 9.2 1.1 9.3 2.5 2.8 1 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Peptidase_M29 PF02073.15 EKX37527.1 - 0.71 8.6 10.0 1.1 7.9 0.1 2.6 3 1 0 3 3 3 0 Thermophilic metalloprotease (M29) FliJ PF02050.16 EKX37527.1 - 0.78 10.0 16.9 1.2 9.4 2.9 2.8 2 1 1 3 3 3 0 Flagellar FliJ protein DUF148 PF02520.17 EKX37527.1 - 0.9 9.7 18.6 2.5 8.2 0.4 3.1 2 1 1 3 3 3 0 Domain of unknown function DUF148 CdiA_C_tRNase PF18664.1 EKX37527.1 - 2.2 8.5 9.9 8.9 6.5 0.1 2.9 3 1 0 3 3 3 0 CdiA C-terminal tRNase domain SOAR PF16533.5 EKX37527.1 - 2.5 8.1 10.7 4.6 7.3 1.4 3.5 2 1 0 3 3 3 0 STIM1 Orai1-activating region MutS_II PF05188.17 EKX37527.1 - 2.5 8.4 6.0 2 8.7 0.8 2.7 2 1 1 3 3 3 0 MutS domain II CCDC85 PF10226.9 EKX37527.1 - 3.1 7.4 15.7 0.032 13.9 4.5 2.7 2 1 0 2 2 2 0 CCDC85 family HIP1_clath_bdg PF16515.5 EKX37527.1 - 4.1 8.1 21.1 3.6 8.2 6.6 3.5 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Serine_rich PF08824.10 EKX37527.1 - 4.3 7.3 17.0 7 6.6 7.2 3.9 3 2 0 3 3 3 0 Serine rich protein interaction domain DUF745 PF05335.13 EKX37527.1 - 6.9 6.4 11.9 3.8 7.2 3.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF745) KAsynt_C_assoc PF16197.5 EKX37527.1 - 7 7.2 7.3 1.8 9.0 0.3 2.9 2 1 1 3 3 3 0 Ketoacyl-synthetase C-terminal extension LIFR_D2 PF17971.1 EKX37528.1 - 0.093 12.9 4.6 3.1 8.0 0.4 2.5 1 1 1 2 2 2 0 Leukemia inhibitory factor receptor D2 domain SL4P PF17618.2 EKX37528.1 - 0.25 11.4 15.1 1.5e+02 2.5 12.8 4.2 1 1 1 2 2 2 0 Uncharacterized Strongylid L4 protein HMA PF00403.26 EKX37528.1 - 0.27 11.7 11.9 22 5.6 0.5 3.9 1 1 1 2 2 2 0 Heavy-metal-associated domain Bact_lectin PF18483.1 EKX37528.1 - 7.2 6.6 7.6 3.6e+02 1.0 7.6 2.6 1 1 0 1 1 1 0 Bacterial lectin STI1 PF17830.1 EKX37529.1 - 0.00025 20.9 0.0 0.00034 20.5 0.0 1.2 1 0 0 1 1 1 1 STI1 domain GerD PF17898.1 EKX37530.1 - 5.6e-05 23.1 2.7 8.5e-05 22.5 2.7 1.2 1 0 0 1 1 1 1 Spore germination GerD central core domain PA14 PF07691.12 EKX37532.1 - 6.3e-35 120.1 0.2 1.3e-06 28.3 0.0 5.3 5 0 0 5 5 5 5 PA14 domain SRCR PF00530.18 EKX37532.1 - 4.9e-17 62.3 4.1 1.3e-16 60.9 4.1 1.7 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Collagen PF01391.18 EKX37532.1 - 3.6e-10 39.5 37.8 7e-09 35.3 21.0 2.5 2 0 0 2 2 2 2 Collagen triple helix repeat (20 copies) bPH_5 PF10882.8 EKX37532.1 - 0.078 13.1 0.1 72 3.5 0.0 4.2 4 0 0 4 4 4 0 Bacterial PH domain Crystall_3 PF08964.10 EKX37532.1 - 0.084 13.1 0.1 0.31 11.3 0.0 2.0 2 0 0 2 2 2 0 Beta/Gamma crystallin SRCR_2 PF15494.6 EKX37532.1 - 0.09 13.3 0.1 0.24 11.9 0.1 1.7 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain Snf7 PF03357.21 EKX37533.1 - 8.4e-32 110.1 20.4 8.4e-32 110.1 20.4 1.4 2 0 0 2 2 2 1 Snf7 DUF2802 PF10975.8 EKX37533.1 - 0.0046 17.1 0.8 0.0046 17.1 0.8 3.5 4 0 0 4 4 4 1 Protein of unknown function (DUF2802) NuA4 PF09340.10 EKX37533.1 - 0.014 15.3 0.3 0.014 15.3 0.3 2.5 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 RNA_pol_Rpb1_5 PF04998.17 EKX37533.1 - 1.2 8.5 3.7 1.7 8.0 3.7 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 BLOC1_2 PF10046.9 EKX37533.1 - 5 7.5 14.5 0.27 11.6 3.2 3.6 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RRP36 PF06102.12 EKX37533.1 - 6 6.8 16.9 0.092 12.7 6.9 2.3 2 1 0 2 2 2 0 rRNA biogenesis protein RRP36 LCD1 PF09798.9 EKX37533.1 - 6.5 5.2 15.7 3.1 6.2 14.1 1.3 1 1 0 1 1 1 0 DNA damage checkpoint protein UPF0767 PF15990.5 EKX37533.1 - 9.8 6.4 6.1 6.7 6.9 0.1 3.0 2 1 1 3 3 3 0 UPF0767 family ATP_bind_1 PF03029.17 EKX37535.1 - 2.3e-84 283.0 0.0 2.6e-84 282.8 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 EKX37535.1 - 0.00085 19.2 0.0 0.0025 17.6 0.0 1.7 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 EKX37535.1 - 0.0036 17.3 0.0 0.0059 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 EKX37535.1 - 0.0066 15.8 0.0 0.35 10.2 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region RNA_helicase PF00910.22 EKX37535.1 - 0.026 14.9 0.0 0.053 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 EKX37535.1 - 0.026 14.4 0.0 7.7 6.4 0.0 2.6 3 0 0 3 3 3 0 RsgA GTPase AAA_18 PF13238.6 EKX37535.1 - 0.047 14.2 0.0 0.092 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EKX37535.1 - 0.065 12.8 0.0 10 5.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 EKX37535.1 - 0.09 12.5 0.0 1.2 8.9 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 EKX37535.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain Sigma54_activat PF00158.26 EKX37535.1 - 0.11 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain Viral_helicase1 PF01443.18 EKX37535.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 EKX37535.1 - 0.15 11.4 0.0 6.8 6.1 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 EKX37535.1 - 0.16 12.2 0.1 0.48 10.7 0.1 1.8 1 1 1 2 2 2 0 AAA domain NTPase_1 PF03266.15 EKX37535.1 - 0.17 11.8 0.1 19 5.1 0.0 2.8 2 1 1 3 3 3 0 NTPase ATPase_2 PF01637.18 EKX37535.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EKX37535.1 - 0.17 11.6 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 EKX37535.1 - 0.18 11.1 0.0 1.2 8.3 0.0 1.9 2 0 0 2 2 2 0 Septin AAA_16 PF13191.6 EKX37535.1 - 0.24 11.8 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain SET PF00856.28 EKX37536.1 - 6.6e-11 42.9 3.1 4.1e-10 40.3 0.2 3.0 2 1 0 2 2 2 1 SET domain BAH PF01426.18 EKX37536.1 - 4.2e-08 33.1 0.0 9.3e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 BAH domain TrmO PF01980.16 EKX37537.1 - 2.1e-34 118.3 0.0 4.6e-34 117.2 0.0 1.5 2 0 0 2 2 2 1 tRNA-methyltransferase O TrmO_C PF18389.1 EKX37537.1 - 0.00019 21.4 0.0 0.00035 20.6 0.0 1.5 1 0 0 1 1 1 1 TrmO C-terminal domain Clusterin PF01093.17 EKX37540.1 - 0.09 11.8 0.2 0.16 11.0 0.2 1.3 1 0 0 1 1 1 0 Clusterin RWP-RK PF02042.15 EKX37542.1 - 5.8e-13 48.6 0.1 1.4e-12 47.4 0.0 1.5 2 0 0 2 2 2 1 RWP-RK domain HTH_AraC PF00165.23 EKX37542.1 - 0.064 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_8 PF02954.19 EKX37542.1 - 0.15 11.8 0.1 0.68 9.8 0.0 2.0 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family baeRF_family12 PF18856.1 EKX37544.1 - 9.5 6.8 6.2 2 9.0 1.1 2.2 2 1 1 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 12 DOG1 PF14144.6 EKX37545.1 - 2.6e-08 34.0 0.1 0.25 11.6 0.0 3.8 3 0 0 3 3 3 3 Seed dormancy control SPO22 PF08631.10 EKX37545.1 - 9.9e-05 21.9 9.4 0.2 11.1 0.5 3.3 2 1 1 3 3 3 2 Meiosis protein SPO22/ZIP4 like DUF4125 PF13526.6 EKX37545.1 - 0.00042 20.0 0.9 1.1 8.8 0.1 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF4125) DUF630 PF04783.12 EKX37545.1 - 0.0012 19.0 13.9 1.2 9.4 0.3 3.7 3 0 0 3 3 3 3 Protein of unknown function (DUF630) DnaB_2 PF07261.11 EKX37545.1 - 0.0012 18.5 0.2 9.7 6.0 0.0 4.0 4 0 0 4 4 4 0 Replication initiation and membrane attachment DUF3880 PF12996.7 EKX37545.1 - 0.0083 16.2 0.0 17 5.5 0.0 3.7 3 2 1 4 4 4 0 DUF based on E. rectale Gene description (DUF3880) FlgN PF05130.12 EKX37545.1 - 0.036 14.6 6.0 98 3.4 0.0 5.1 1 1 4 5 5 5 0 FlgN protein DUF1978 PF09321.10 EKX37545.1 - 0.038 13.3 17.5 0.19 11.0 2.6 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF1978) DUF1758 PF05585.12 EKX37545.1 - 0.062 13.1 0.0 21 4.9 0.0 2.7 3 0 0 3 3 3 0 Putative peptidase (DUF1758) DUF1298 PF06974.13 EKX37545.1 - 0.13 12.2 0.4 79 3.2 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1298) CC2D2AN-C2 PF15625.6 EKX37545.1 - 0.46 10.2 4.7 13 5.4 0.4 2.6 3 0 0 3 3 3 0 CC2D2A N-terminal C2 domain TPD52 PF04201.15 EKX37545.1 - 0.88 9.2 3.8 36 3.9 0.2 3.4 3 0 0 3 3 3 0 Tumour protein D52 family SOCS_box PF07525.16 EKX37545.1 - 1.2 9.6 5.6 1e+02 3.4 0.0 3.9 3 0 0 3 3 3 0 SOCS box DUF2852 PF11014.8 EKX37545.1 - 1.6 8.9 23.4 6.4 7.0 0.1 4.4 1 1 4 5 5 5 0 Protein of unknown function (DUF2852) HTH_18 PF12833.7 EKX37545.1 - 1.9 8.8 12.1 6.3 7.1 0.9 3.7 3 0 0 3 3 3 0 Helix-turn-helix domain DUF2894 PF11445.8 EKX37545.1 - 2 8.8 8.7 16 5.9 0.4 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF2894) HAMP PF00672.25 EKX37545.1 - 2.9 8.3 7.0 2.4e+02 2.2 0.0 5.5 6 0 0 6 6 6 0 HAMP domain DUF3523 PF12037.8 EKX37545.1 - 4.6 6.6 17.7 6.5 6.0 4.6 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF3523) Myb_CC_LHEQLE PF14379.6 EKX37545.1 - 4.7 7.0 7.8 27 4.6 1.0 3.1 2 0 0 2 2 2 0 MYB-CC type transfactor, LHEQLE motif DOG1 PF14144.6 EKX37546.1 - 3.6e-08 33.5 0.0 0.97 9.7 0.0 3.8 3 0 0 3 3 3 3 Seed dormancy control DUF3880 PF12996.7 EKX37546.1 - 1.2e-05 25.3 0.0 10 6.3 0.0 4.4 3 2 2 5 5 5 0 DUF based on E. rectale Gene description (DUF3880) DUF4125 PF13526.6 EKX37546.1 - 1.6e-05 24.7 5.2 0.6 9.7 0.1 3.2 1 1 0 3 3 3 3 Protein of unknown function (DUF4125) DnaB_2 PF07261.11 EKX37546.1 - 1.6e-05 24.5 0.0 5.5 6.8 0.0 3.5 3 0 0 3 3 3 3 Replication initiation and membrane attachment DUF1758 PF05585.12 EKX37546.1 - 0.00013 21.8 0.0 8.1 6.2 0.0 3.5 3 1 0 3 3 3 0 Putative peptidase (DUF1758) DUF630 PF04783.12 EKX37546.1 - 0.0013 18.8 16.0 1.5 9.1 1.0 3.8 3 0 0 3 3 3 3 Protein of unknown function (DUF630) MCM6_C PF18263.1 EKX37546.1 - 0.0017 18.6 5.3 9.8 6.5 0.2 4.2 3 2 0 3 3 3 0 MCM6 C-terminal winged-helix domain FlgN PF05130.12 EKX37546.1 - 0.0044 17.5 4.2 31 5.1 0.1 4.6 1 1 2 4 4 4 0 FlgN protein RINGv PF12906.7 EKX37546.1 - 0.012 15.8 1.3 39 4.5 0.0 3.6 3 0 0 3 3 3 0 RING-variant domain DUF1298 PF06974.13 EKX37546.1 - 0.021 14.8 0.2 49 3.9 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1298) DUF2894 PF11445.8 EKX37546.1 - 0.026 15.0 11.3 9.7 6.6 0.6 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF2894) ThiS PF02597.20 EKX37546.1 - 0.04 14.5 0.1 16 6.2 0.0 2.6 2 0 0 2 2 2 0 ThiS family SoPB_HTH PF18090.1 EKX37546.1 - 0.041 14.0 0.9 1.3e+02 2.8 0.0 4.7 3 2 2 5 5 5 0 Centromere-binding protein HTH domain TPX2 PF06886.11 EKX37546.1 - 0.046 14.0 8.2 5.3 7.4 0.6 4.0 3 0 0 3 3 3 0 Targeting protein for Xklp2 (TPX2) IPT PF01745.16 EKX37546.1 - 0.09 12.2 6.9 12 5.2 0.2 3.3 3 0 0 3 3 3 0 Isopentenyl transferase HAMP PF00672.25 EKX37546.1 - 0.092 13.1 7.5 1.5e+02 2.9 0.0 6.3 6 0 0 6 6 6 0 HAMP domain UPF0231 PF06062.11 EKX37546.1 - 0.12 12.6 4.2 3.5 7.9 0.1 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0231) Tsp45I PF06300.12 EKX37546.1 - 0.13 11.8 5.4 6.7 6.2 0.2 3.0 2 1 0 3 3 3 0 Tsp45I type II restriction enzyme DUF4145 PF13643.6 EKX37546.1 - 0.34 11.0 4.0 74 3.6 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4145) DUF2852 PF11014.8 EKX37546.1 - 1.2 9.3 27.5 3.3 7.9 2.8 5.0 1 1 5 6 6 6 0 Protein of unknown function (DUF2852) SOCS_box PF07525.16 EKX37546.1 - 3 8.3 8.3 73 3.9 0.2 3.5 3 0 0 3 3 3 0 SOCS box SesA PF17107.5 EKX37546.1 - 4.3 7.5 7.4 79 3.5 0.1 3.7 4 0 0 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases CC2D2AN-C2 PF15625.6 EKX37546.1 - 5.9 6.6 6.1 7.8 6.2 0.5 2.3 2 0 0 2 2 2 0 CC2D2A N-terminal C2 domain DUF630 PF04783.12 EKX37547.1 - 0.0016 18.6 6.9 0.37 11.0 0.5 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF630) FlgN PF05130.12 EKX37547.1 - 0.003 18.1 1.4 0.63 10.5 0.1 2.6 1 1 1 2 2 2 1 FlgN protein EDS1_EP PF18117.1 EKX37547.1 - 0.004 17.6 2.3 18 5.8 0.0 4.1 1 1 3 4 4 4 0 Enhanced disease susceptibility 1 protein EP domain Tsp45I PF06300.12 EKX37547.1 - 0.018 14.6 0.8 0.068 12.7 0.2 1.9 1 1 0 2 2 2 0 Tsp45I type II restriction enzyme HAMP PF00672.25 EKX37547.1 - 0.022 15.2 1.3 86 3.6 0.0 4.4 4 0 0 4 4 4 0 HAMP domain DUF334 PF03904.13 EKX37547.1 - 0.028 13.9 0.6 0.028 13.9 0.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF334) SoPB_HTH PF18090.1 EKX37547.1 - 0.052 13.7 2.3 68 3.7 0.0 3.9 2 2 2 4 4 4 0 Centromere-binding protein HTH domain DUF2852 PF11014.8 EKX37547.1 - 0.053 13.7 11.9 1.1 9.4 0.2 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2852) DOG1 PF14144.6 EKX37547.1 - 0.096 12.9 0.0 0.47 10.7 0.0 2.3 2 0 0 2 2 2 0 Seed dormancy control Helicase_IV_N PF12462.8 EKX37547.1 - 0.11 12.4 6.2 0.093 12.7 0.9 2.2 2 0 0 2 2 2 0 DNA helicase IV / RNA helicase N terminal DUF1959 PF09218.10 EKX37547.1 - 0.13 12.4 5.3 1.2 9.2 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1959) DUF3880 PF12996.7 EKX37547.1 - 0.13 12.3 0.0 5.6 7.1 0.0 3.1 2 2 2 4 4 4 0 DUF based on E. rectale Gene description (DUF3880) DUF1298 PF06974.13 EKX37547.1 - 0.16 12.0 0.1 22 5.0 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1298) DUF2894 PF11445.8 EKX37547.1 - 0.36 11.3 3.4 7.3 7.0 1.1 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2894) HTH_18 PF12833.7 EKX37547.1 - 0.58 10.5 9.1 2.4 8.5 1.1 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain Nas2_N PF18265.1 EKX37548.1 - 0.047 13.6 5.4 0.28 11.1 0.1 2.7 2 1 1 3 3 3 0 Nas2 N_terminal domain Fib_alpha PF08702.10 EKX37548.1 - 1 9.6 9.0 1.7 8.8 0.1 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.9 EKX37548.1 - 1.1 9.3 15.8 0.58 10.2 0.2 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF745 PF05335.13 EKX37548.1 - 5.9 6.6 7.0 10 5.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) HYLS1_C PF15311.6 EKX37550.1 - 2.1e-05 25.2 15.4 4.8e-05 24.0 1.0 2.9 2 2 1 3 3 3 2 Hydrolethalus syndrome protein 1 C-terminus KfrA_N PF11740.8 EKX37550.1 - 0.0017 19.0 1.6 0.0042 17.8 1.6 1.7 1 0 0 1 1 1 1 Plasmid replication region DNA-binding N-term GGA_N-GAT PF18308.1 EKX37550.1 - 0.041 13.5 0.1 0.59 9.8 0.0 2.3 2 0 0 2 2 2 0 GGA N-GAT domain DUF2789 PF10982.8 EKX37552.1 - 8 6.7 10.4 1.3e+02 2.9 0.0 4.3 4 1 1 5 5 5 0 Protein of unknown function (DUF2789) DUF812 PF05667.11 EKX37553.1 - 0.00036 19.6 30.6 0.00036 19.6 30.6 4.8 1 1 3 4 4 4 2 Protein of unknown function (DUF812) HMG_box_5 PF14887.6 EKX37553.1 - 0.028 14.4 12.9 0.43 10.6 0.5 4.6 3 0 0 3 3 3 0 HMG (high mobility group) box 5 CENP-F_leu_zip PF10473.9 EKX37553.1 - 1.7 8.7 208.3 1.4 8.9 33.2 8.3 3 2 5 8 8 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PAS_9 PF13426.7 EKX37554.1 - 0.00093 19.4 0.0 0.0037 17.5 0.0 1.9 1 1 1 2 2 2 1 PAS domain RTTN_N PF14726.6 EKX37555.1 - 3.8e-16 59.7 0.0 5.1e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Rotatin, an armadillo repeat protein, centriole functioning HEAT PF02985.22 EKX37555.1 - 0.1 12.9 0.0 21 5.7 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat TFIID_NTD2 PF04494.15 EKX37560.1 - 7.3e-14 52.1 0.0 1.3e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANF_receptor PF01094.28 EKX37561.1 - 9.4e-77 258.5 0.0 2.6e-44 151.8 0.0 2.1 2 0 0 2 2 2 2 Receptor family ligand binding region Peripla_BP_6 PF13458.6 EKX37561.1 - 1.2e-15 58.1 0.0 1.1e-06 28.5 0.0 2.7 3 0 0 3 3 3 2 Periplasmic binding protein Ammonium_transp PF00909.21 EKX37562.1 - 2.5e-116 388.7 34.0 3e-116 388.4 34.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family zf-RING_2 PF13639.6 EKX37563.1 - 5.9e-11 42.5 11.3 1.2e-10 41.5 11.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX37563.1 - 4e-10 39.4 11.3 8.1e-10 38.4 11.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX37563.1 - 5.3e-08 33.0 11.3 2.1e-07 31.1 11.3 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EKX37563.1 - 7.5e-07 29.1 4.5 1.7e-06 27.9 4.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EKX37563.1 - 3.5e-05 23.6 13.7 8.2e-05 22.4 13.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EKX37563.1 - 4.2e-05 23.3 10.7 0.0001 22.1 10.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EKX37563.1 - 5.1e-05 22.9 2.1 0.00013 21.6 2.1 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-Nse PF11789.8 EKX37563.1 - 0.0027 17.5 5.8 0.0063 16.3 5.8 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 EKX37563.1 - 0.013 15.2 12.3 0.023 14.3 12.3 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EKX37563.1 - 0.029 14.3 13.3 0.06 13.3 13.3 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 EKX37563.1 - 0.07 13.2 9.3 0.19 11.8 9.3 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger AMP-binding PF00501.28 EKX37564.1 - 2.4e-86 290.0 0.0 2.9e-86 289.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EKX37564.1 - 2e-21 76.8 0.1 3.9e-21 75.8 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EKX37564.1 - 1.8e-20 72.6 1.7 4.4e-20 71.3 1.7 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DapB_C PF05173.14 EKX37565.1 - 3.5e-42 143.3 0.4 5e-42 142.8 0.4 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.20 EKX37565.1 - 9.9e-24 83.8 0.1 4.1e-23 81.8 0.0 2.1 2 1 1 3 3 3 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 EKX37565.1 - 0.00025 21.5 0.0 0.00059 20.3 0.0 1.7 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EKX37565.1 - 0.025 14.8 0.0 0.049 13.9 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Gp_dh_N PF00044.24 EKX37565.1 - 0.053 13.9 0.1 0.27 11.6 0.0 2.3 2 1 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain EF-hand_7 PF13499.6 EKX37566.1 - 1.3e-35 121.7 31.5 4.6e-11 43.0 0.4 6.1 2 2 5 7 7 7 6 EF-hand domain pair EF-hand_1 PF00036.32 EKX37566.1 - 1e-32 109.2 24.1 1.6e-05 24.1 0.7 7.5 7 0 0 7 7 7 6 EF hand EF-hand_5 PF13202.6 EKX37566.1 - 6.3e-31 104.5 21.6 1.9e-05 24.0 0.1 6.6 6 0 0 6 6 6 5 EF hand EF-hand_6 PF13405.6 EKX37566.1 - 1.5e-29 99.3 20.6 0.00034 20.3 0.3 7.8 8 0 0 8 8 8 6 EF-hand domain EF-hand_8 PF13833.6 EKX37566.1 - 2.8e-26 91.1 20.8 2.9e-06 27.0 0.3 6.9 3 2 4 7 7 7 6 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX37566.1 - 2.2e-18 66.6 11.0 1.4e-08 35.1 0.1 4.0 3 1 1 4 4 4 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EKX37566.1 - 1.1e-05 25.3 11.2 0.14 12.1 0.2 4.8 2 2 3 5 5 5 4 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 EKX37566.1 - 8.3e-05 22.7 0.7 17 5.7 0.0 4.8 3 1 1 4 4 4 0 Dockerin type I domain Sigma70_r1_1 PF03979.14 EKX37566.1 - 0.062 13.4 14.3 0.79 9.8 0.4 4.9 5 0 0 5 5 5 0 Sigma-70 factor, region 1.1 RPAP3_C PF13877.6 EKX37566.1 - 0.15 12.7 1.4 0.49 11.0 0.8 2.3 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 TFIIE_beta PF02186.15 EKX37566.1 - 0.56 10.5 0.1 0.56 10.5 0.1 3.5 5 0 0 5 5 5 0 TFIIE beta subunit core domain Ish1 PF10281.9 EKX37567.1 - 0.052 13.9 0.2 0.092 13.1 0.2 1.4 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein EF-hand_7 PF13499.6 EKX37568.1 - 3.2e-11 43.5 0.7 1.1e-10 41.8 0.7 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX37568.1 - 4.7e-11 41.4 0.7 0.00033 20.0 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EKX37568.1 - 1.5e-09 37.0 0.4 0.0063 16.3 0.0 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 EKX37568.1 - 4.8e-07 29.5 0.7 0.00033 20.4 0.1 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX37568.1 - 9.1e-06 24.9 4.6 0.00044 19.6 0.0 3.4 3 1 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.9 EKX37568.1 - 5.1e-05 23.6 2.1 0.00011 22.5 0.0 2.3 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Mod_r PF07200.13 EKX37568.1 - 0.69 10.0 11.0 2.1 8.4 11.0 1.8 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein XhlA PF10779.9 EKX37568.1 - 1.5 9.1 6.0 1.1 9.5 1.1 3.0 3 0 0 3 3 3 0 Haemolysin XhlA FapA PF03961.13 EKX37568.1 - 4.6 5.7 11.7 0.9 8.1 7.9 1.7 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF1664 PF07889.12 EKX37568.1 - 6.7 6.8 18.1 1.6 8.8 5.3 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) GHMP_kinases_N PF00288.26 EKX37569.1 - 7e-11 42.2 0.0 7e-11 42.2 0.0 2.7 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EKX37569.1 - 5.5e-06 26.7 0.0 1.5e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal DUF823 PF05689.11 EKX37569.1 - 0.036 13.8 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF823) DUF445 PF04286.12 EKX37570.1 - 0.0026 17.6 65.6 0.0087 15.9 51.3 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF445) 2-oxogl_dehyd_N PF16078.5 EKX37571.1 - 0.42 10.2 1.6 0.6 9.7 0.1 1.9 2 0 0 2 2 2 0 2-oxoglutarate dehydrogenase N-terminus Aminotran_1_2 PF00155.21 EKX37574.1 - 1.3e-71 241.7 0.0 1.4e-71 241.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II RWP-RK PF02042.15 EKX37575.1 - 4.1e-14 52.3 0.0 8.4e-14 51.3 0.0 1.6 2 0 0 2 2 2 1 RWP-RK domain HTH_8 PF02954.19 EKX37575.1 - 0.082 12.7 0.1 0.27 11.1 0.0 1.8 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family HTH_31 PF13560.6 EKX37575.1 - 0.15 12.5 0.0 7.2 7.0 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain RWP-RK PF02042.15 EKX37576.1 - 2.9e-14 52.8 0.0 6e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX37576.1 - 0.088 12.6 0.1 0.28 11.0 0.1 1.8 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family RWP-RK PF02042.15 EKX37577.1 - 1.8e-20 72.7 0.1 2.9e-20 72.0 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain Corazonin PF17308.2 EKX37577.1 - 0.02 15.2 0.0 0.024 15.0 0.0 1.1 1 0 0 1 1 1 0 Pro-corazonin HTH_Mga PF08280.11 EKX37577.1 - 0.064 13.3 0.1 5.9 7.0 0.1 2.4 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain CRR7 PF12095.8 EKX37578.1 - 0.87 10.1 3.8 2 8.9 1.2 2.4 3 0 0 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 MAT1 PF06391.13 EKX37578.1 - 1.1 9.1 9.0 1.8 8.3 8.6 1.6 1 1 1 2 2 2 0 CDK-activating kinase assembly factor MAT1 PCIF1_WW PF12237.8 EKX37579.1 - 6e-11 42.3 0.0 7.2e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain Ank_5 PF13857.6 EKX37580.1 - 1.2e-10 41.4 0.0 1.2e-05 25.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX37580.1 - 1.2e-09 38.7 0.0 4.6e-07 30.3 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX37580.1 - 1.2e-08 35.3 0.0 0.012 16.2 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX37580.1 - 6.6e-06 26.1 0.0 0.77 10.5 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EKX37580.1 - 7.5e-06 26.2 0.0 0.0025 18.2 0.0 3.9 3 1 0 3 3 3 1 Ankyrin repeat YajC PF02699.15 EKX37580.1 - 0.01 15.7 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit MRP-S25 PF13741.6 EKX37581.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S25 DUF5486 PF17588.2 EKX37582.1 - 0.072 13.0 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5486) IQ PF00612.27 EKX37583.1 - 6e-28 94.0 95.7 0.016 15.0 1.1 19.3 19 0 0 19 19 19 16 IQ calmodulin-binding motif WW PF00397.26 EKX37583.1 - 1.4e-14 53.8 2.7 3.2e-07 30.3 0.3 3.6 3 0 0 3 3 3 3 WW domain HC2 PF07382.11 EKX37583.1 - 0.001 19.2 53.7 0.001 19.2 53.7 4.0 3 1 1 4 4 4 1 Histone H1-like nucleoprotein HC2 CorA PF01544.18 EKX37583.1 - 0.11 11.8 3.0 0.51 9.6 3.0 2.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein RCC1 PF00415.18 EKX37584.1 - 1.2e-24 86.7 6.1 1.4e-12 48.0 0.0 4.2 3 1 1 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX37584.1 - 2.4e-19 68.6 11.7 5.8e-08 32.3 0.5 4.1 3 1 1 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat Mito_carr PF00153.27 EKX37585.1 - 2.1e-36 123.7 4.4 1.2e-13 50.8 0.1 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Gly-zipper_YMGG PF13441.6 EKX37585.1 - 0.35 10.6 5.8 0.45 10.3 0.2 2.5 2 0 0 2 2 2 0 YMGG-like Gly-zipper Alpha_kinase PF02816.18 EKX37586.1 - 4.6e-56 189.9 0.0 6.9e-56 189.3 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family C2 PF00168.30 EKX37586.1 - 5.7e-09 36.2 0.0 2.4e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 C2 domain GAF PF01590.26 EKX37589.1 - 1.4e-05 25.8 0.0 3e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 GAF domain cNMP_binding PF00027.29 EKX37589.1 - 0.0037 17.3 0.0 0.0072 16.4 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain GAF_3 PF13492.6 EKX37589.1 - 0.011 16.1 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 GAF domain RtxA PF07634.11 EKX37589.1 - 0.16 12.6 0.9 0.48 11.1 0.2 2.2 2 0 0 2 2 2 0 RtxA repeat LMF1 PF06762.14 EKX37590.1 - 9.4e-63 212.8 4.0 1.3e-62 212.4 4.0 1.1 1 0 0 1 1 1 1 Lipase maturation factor MIP PF00230.20 EKX37591.1 - 1.1e-30 107.1 14.6 3.7e-30 105.3 14.6 1.7 1 1 0 1 1 1 1 Major intrinsic protein Senescence PF06911.12 EKX37592.1 - 0.004 17.5 0.1 0.0065 16.8 0.1 1.3 1 0 0 1 1 1 1 Senescence-associated protein PDEase_I PF00233.19 EKX37593.1 - 3.1e-40 138.4 0.8 5.5e-40 137.6 0.8 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 EKX37593.1 - 7.4e-10 39.6 0.1 4e-09 37.2 0.0 2.1 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 EKX37593.1 - 0.036 14.3 0.0 0.46 10.8 0.0 2.3 1 1 1 2 2 2 0 GAF domain DUF1622 PF07784.11 EKX37594.1 - 4.9e-10 39.2 0.1 9.9e-10 38.2 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1622) Herpes_UL36 PF03586.13 EKX37594.1 - 0.19 11.0 0.0 0.42 9.9 0.0 1.5 2 0 0 2 2 2 0 Herpesvirus UL36 tegument protein DHC_N1 PF08385.12 EKX37595.1 - 2e-141 472.4 6.4 2e-141 472.4 6.4 3.8 6 0 0 6 6 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 EKX37595.1 - 2.8e-86 290.1 6.7 2.8e-86 290.1 6.7 5.0 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 EKX37595.1 - 2.9e-55 187.6 0.0 1.3e-54 185.4 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 EKX37595.1 - 9.9e-52 176.1 0.6 9.9e-52 176.1 0.6 3.4 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 EKX37595.1 - 1.6e-46 158.1 0.1 3.6e-42 143.9 0.0 3.5 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_9 PF12781.7 EKX37595.1 - 7.7e-44 149.4 1.0 3.4e-43 147.3 0.0 2.8 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_8 PF12780.7 EKX37595.1 - 1.1e-37 129.8 0.4 2.3e-36 125.5 0.0 3.5 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 MT PF12777.7 EKX37595.1 - 8.3e-19 67.8 2.7 2e-18 66.5 2.7 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 EKX37595.1 - 9.1e-19 67.8 0.7 4.2e-18 65.7 0.7 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EKX37595.1 - 1.9e-15 57.0 5.3 2e-13 50.5 0.0 5.3 5 0 0 5 5 3 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 EKX37595.1 - 6.2e-10 39.1 0.0 1.9e-09 37.5 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 EKX37595.1 - 7.6e-10 39.4 0.3 0.015 15.7 0.0 5.3 4 0 0 4 4 3 2 AAA ATPase domain AAA_22 PF13401.6 EKX37595.1 - 9e-10 39.0 3.3 0.00015 22.1 0.0 5.9 6 0 0 6 6 4 2 AAA domain AAA_5 PF07728.14 EKX37595.1 - 3.1e-09 37.0 0.0 0.15 12.1 0.0 5.2 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA PF00004.29 EKX37595.1 - 3.5e-08 33.9 2.8 0.1 13.0 0.0 6.3 6 0 0 6 6 6 1 ATPase family associated with various cellular activities (AAA) AAA_lid_1 PF17857.1 EKX37595.1 - 7.3e-08 32.6 0.0 3.5e-07 30.4 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain RsgA_GTPase PF03193.16 EKX37595.1 - 9.2e-06 25.7 0.1 0.29 11.0 0.0 3.4 3 0 0 3 3 2 2 RsgA GTPase NACHT PF05729.12 EKX37595.1 - 5.6e-05 23.1 1.0 1.2 9.0 0.0 4.3 4 0 0 4 4 3 2 NACHT domain AAA_18 PF13238.6 EKX37595.1 - 8.4e-05 23.1 0.2 0.14 12.7 0.0 5.2 5 0 0 5 5 3 1 AAA domain Sigma54_activat PF00158.26 EKX37595.1 - 0.00013 21.7 0.0 0.49 10.1 0.0 3.9 4 0 0 4 4 3 1 Sigma-54 interaction domain DUF724 PF05266.14 EKX37595.1 - 0.00017 21.5 3.2 0.00017 21.5 3.2 4.2 3 0 0 3 3 3 1 Protein of unknown function (DUF724) AAA_30 PF13604.6 EKX37595.1 - 0.00025 20.8 0.0 1.3 8.7 0.0 3.5 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 EKX37595.1 - 0.0003 20.6 0.0 0.062 13.0 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 EKX37595.1 - 0.00065 19.5 0.0 0.2 11.4 0.0 2.8 2 0 0 2 2 2 1 IstB-like ATP binding protein NTPase_1 PF03266.15 EKX37595.1 - 0.00078 19.4 0.8 0.55 10.1 0.0 4.1 3 0 0 3 3 3 1 NTPase AAA_28 PF13521.6 EKX37595.1 - 0.001 19.3 0.0 0.32 11.2 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 EKX37595.1 - 0.0011 19.1 0.3 1.9 8.7 0.0 4.7 4 1 1 5 5 4 1 AAA domain AAA_29 PF13555.6 EKX37595.1 - 0.0013 18.4 5.0 0.26 11.1 0.1 3.9 4 0 0 4 4 4 1 P-loop containing region of AAA domain Roc PF08477.13 EKX37595.1 - 0.0016 18.7 0.1 1.2 9.4 0.1 3.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 EKX37595.1 - 0.0022 18.0 0.0 0.32 10.9 0.0 3.1 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EKX37595.1 - 0.0025 18.2 0.1 3.1 8.2 0.0 3.2 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 EKX37595.1 - 0.0028 17.4 0.2 3.7 7.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain Septin PF00735.18 EKX37595.1 - 0.0029 16.9 0.2 0.36 10.0 0.1 2.5 2 0 0 2 2 2 1 Septin AAA_14 PF13173.6 EKX37595.1 - 0.0039 17.2 0.0 0.14 12.2 0.0 3.1 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EKX37595.1 - 0.0069 16.9 6.6 2.8 8.4 0.0 4.5 4 0 0 4 4 3 1 ABC transporter NB-ARC PF00931.22 EKX37595.1 - 0.0069 15.6 1.3 0.25 10.5 0.0 3.3 3 0 0 3 3 2 1 NB-ARC domain Rad17 PF03215.15 EKX37595.1 - 0.007 16.3 0.1 0.21 11.5 0.0 3.3 3 0 0 3 3 2 1 Rad17 P-loop domain AAA_19 PF13245.6 EKX37595.1 - 0.0073 16.6 0.5 13 6.2 0.0 4.1 4 0 0 4 4 3 0 AAA domain TniB PF05621.11 EKX37595.1 - 0.0086 15.5 1.7 0.7 9.3 0.0 4.1 5 0 0 5 5 3 1 Bacterial TniB protein ATPase PF06745.13 EKX37595.1 - 0.01 15.2 0.1 0.35 10.2 0.0 3.2 2 0 0 2 2 2 0 KaiC MMR_HSR1 PF01926.23 EKX37595.1 - 0.012 15.7 0.0 3.1 7.9 0.0 3.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase IIGP PF05049.13 EKX37595.1 - 0.012 14.7 0.0 0.14 11.2 0.1 2.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) KAP_NTPase PF07693.14 EKX37595.1 - 0.013 14.8 0.1 6.1 6.0 0.0 2.9 2 0 0 2 2 2 0 KAP family P-loop domain Mg_chelatase PF01078.21 EKX37595.1 - 0.016 14.6 0.3 4.7 6.5 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.17 EKX37595.1 - 0.017 14.9 1.0 30 4.3 0.0 5.0 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein T2SSE PF00437.20 EKX37595.1 - 0.02 14.0 0.0 0.24 10.4 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 EKX37595.1 - 0.021 14.2 3.1 4.6 6.5 0.0 4.2 5 0 0 5 5 3 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 EKX37595.1 - 0.027 13.8 0.0 3.7 6.8 0.0 3.4 3 0 0 3 3 2 0 Zeta toxin DUF815 PF05673.13 EKX37595.1 - 0.036 13.2 0.0 0.64 9.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 EKX37595.1 - 0.066 13.3 3.5 0.52 10.4 0.0 4.1 4 0 0 4 4 2 0 Sigma-54 interaction domain MeaB PF03308.16 EKX37595.1 - 0.079 11.9 0.0 1.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 EKX37595.1 - 0.13 11.8 0.1 3.2 7.3 0.1 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain cobW PF02492.19 EKX37595.1 - 0.16 11.5 0.1 3.9 7.0 0.0 2.9 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain MscS_porin PF12795.7 EKX37595.1 - 1.1 8.8 19.7 0.04 13.5 3.6 3.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain SKA1 PF07160.12 EKX37595.1 - 1.3 8.8 14.4 0.34 10.7 2.9 3.7 3 0 0 3 3 2 0 Spindle and kinetochore-associated protein 1 TPR_MLP1_2 PF07926.12 EKX37595.1 - 2.1 8.4 31.7 0.24 11.5 3.9 5.0 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Ion_trans_2 PF07885.16 EKX37596.1 - 1.2e-10 41.2 1.4 4.3e-10 39.4 1.4 2.0 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EKX37596.1 - 1.7e-10 40.5 6.9 3.2e-10 39.6 6.9 1.4 1 1 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 EKX37596.1 - 0.00014 21.9 0.0 0.00031 20.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF3980 PF13140.6 EKX37596.1 - 0.27 11.7 2.9 3.2 8.3 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3980) PPR_2 PF13041.6 EKX37597.1 - 1.5e-30 105.1 3.4 5.7e-15 55.3 0.0 4.5 2 1 2 4 4 4 4 PPR repeat family PPR_1 PF12854.7 EKX37597.1 - 3.3e-30 103.5 0.4 2.1e-06 27.3 0.0 5.1 5 0 0 5 5 5 4 PPR repeat PPR PF01535.20 EKX37597.1 - 4.5e-29 98.6 4.9 2.9e-06 27.1 0.1 5.4 5 0 0 5 5 5 4 PPR repeat PPR_3 PF13812.6 EKX37597.1 - 1.5e-17 63.4 0.1 6.3e-09 35.8 0.0 3.8 1 1 4 5 5 5 4 Pentatricopeptide repeat domain PPR_long PF17177.4 EKX37597.1 - 1.3e-14 54.1 0.2 7.2e-09 35.3 0.0 2.3 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EKX37597.1 - 0.01 16.6 0.1 0.24 12.3 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3856 PF12968.7 EKX37597.1 - 0.02 15.0 0.1 0.041 14.0 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) Glyco_hydro_46 PF01374.18 EKX37597.1 - 0.068 12.8 0.1 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 46 MutS_V PF00488.21 EKX37598.1 - 7.1e-85 283.8 0.6 1.2e-84 283.0 0.6 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EKX37598.1 - 5.4e-32 111.6 0.0 4.3e-31 108.6 0.0 2.2 1 1 1 2 2 2 1 MutS domain III MutS_II PF05188.17 EKX37598.1 - 7.4e-19 68.4 0.1 2.3e-18 66.8 0.1 1.8 1 0 0 1 1 1 1 MutS domain II MutS_I PF01624.20 EKX37598.1 - 1e-16 61.1 0.0 2.9e-16 59.7 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 EKX37598.1 - 8.8e-09 35.6 0.9 2e-08 34.5 0.2 2.0 2 0 0 2 2 2 1 MutS family domain IV AAA_23 PF13476.6 EKX37598.1 - 1.2 9.6 0.0 1.2 9.6 0.0 3.2 3 1 0 3 3 3 0 AAA domain IF-2B PF01008.17 EKX37599.1 - 6.7e-32 110.8 0.0 2.8e-23 82.5 0.0 2.1 1 1 1 2 2 2 2 Initiation factor 2 subunit family Pkinase PF00069.25 EKX37600.1 - 5.9e-65 219.2 0.0 6.7e-65 219.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX37600.1 - 6.8e-33 114.0 0.0 8.8e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EKX37600.1 - 1.2e-06 27.7 0.0 0.0027 16.7 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain Kinase-like PF14531.6 EKX37600.1 - 0.0001 21.7 0.0 0.00029 20.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EKX37600.1 - 0.0035 17.3 0.6 0.0063 16.5 0.3 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family ABC1 PF03109.16 EKX37600.1 - 0.16 12.1 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Creatinase_N_2 PF16189.5 EKX37601.1 - 5.4e-46 156.6 0.0 1.2e-45 155.5 0.0 1.6 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Creatinase_N PF01321.18 EKX37601.1 - 2.2e-19 70.4 0.1 1.5e-13 51.5 0.0 2.3 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain CRR7 PF12095.8 EKX37601.1 - 0.017 15.5 0.7 5.7 7.5 0.1 2.7 2 0 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 PAP2 PF01569.21 EKX37602.1 - 1.3e-15 57.4 0.1 3.6e-15 55.9 0.1 1.7 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 EKX37602.1 - 0.0019 17.9 0.0 0.0028 17.4 0.0 1.4 1 1 0 1 1 1 1 PAP2 superfamily ThiI PF02568.14 EKX37602.1 - 0.1 12.2 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) DUF962 PF06127.11 EKX37603.1 - 0.14 12.2 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF962) Ribonuclease_T2 PF00445.18 EKX37604.1 - 1e-43 149.7 0.2 1.2e-43 149.5 0.2 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Med22 PF06179.12 EKX37606.1 - 0.0071 16.5 0.7 0.0085 16.3 0.7 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex SlyX PF04102.12 EKX37606.1 - 0.058 14.0 0.8 0.11 13.1 0.3 1.6 2 0 0 2 2 2 0 SlyX PDZ PF00595.24 EKX37607.1 - 7.8e-06 26.2 0.1 1.4e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX37607.1 - 4.5e-05 23.2 0.2 9.4e-05 22.2 0.2 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX37607.1 - 0.0042 17.4 0.0 0.0061 16.9 0.0 1.2 1 0 0 1 1 1 1 PDZ domain Hema_stalk PF08720.10 EKX37608.1 - 0.59 9.8 5.6 0.15 11.8 0.3 2.7 2 1 1 3 3 3 0 Influenza C hemagglutinin stalk Y2_Tnp PF04986.13 EKX37608.1 - 10 6.2 7.0 23 5.0 4.3 3.2 1 1 1 2 2 2 0 Putative transposase Kringle PF00051.18 EKX37610.1 - 5.3e-12 45.9 0.9 3.9e-11 43.1 0.9 2.2 1 1 0 1 1 1 1 Kringle domain TAL_FSA PF00923.19 EKX37612.1 - 2.4e-79 266.7 0.0 2.8e-79 266.4 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Nop10p PF04135.12 EKX37613.1 - 1.8e-22 79.1 0.7 2e-22 79.0 0.7 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family PAS_9 PF13426.7 EKX37615.1 - 0.0021 18.3 0.0 0.004 17.4 0.0 1.6 1 0 0 1 1 1 1 PAS domain ADK PF00406.22 EKX37616.1 - 2.1e-49 167.5 0.0 2.6e-49 167.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EKX37616.1 - 7.1e-17 62.1 0.0 1.4e-16 61.1 0.0 1.4 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 EKX37616.1 - 7.1e-14 51.5 0.0 1.9e-13 50.1 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid ADK PF00406.22 EKX37617.1 - 4.1e-55 186.0 0.0 4.9e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EKX37617.1 - 1.8e-22 80.2 0.1 3.4e-22 79.3 0.0 1.4 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 EKX37617.1 - 6.5e-14 51.6 0.0 1.7e-13 50.3 0.0 1.7 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EKX37617.1 - 0.0012 19.4 0.0 0.003 18.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EKX37617.1 - 0.0033 17.6 0.0 0.0072 16.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain WD40 PF00400.32 EKX37619.1 - 7.7e-23 80.4 19.8 0.00041 21.1 0.1 9.3 9 1 0 9 9 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX37619.1 - 9.8e-06 25.8 0.1 22 5.4 0.0 5.6 4 2 2 6 6 6 0 Anaphase-promoting complex subunit 4 WD40 domain Raftlin PF15250.6 EKX37619.1 - 0.014 14.2 20.6 0.022 13.5 20.6 1.3 1 0 0 1 1 1 0 Raftlin TFIIA PF03153.13 EKX37619.1 - 0.02 14.9 39.8 0.037 14.0 39.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Caldesmon PF02029.15 EKX37619.1 - 0.087 11.6 49.3 0.13 11.0 49.3 1.1 1 0 0 1 1 1 0 Caldesmon DUF4045 PF13254.6 EKX37619.1 - 0.39 10.3 31.0 0.77 9.3 31.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) BAF1_ABF1 PF04684.13 EKX37619.1 - 0.63 9.0 25.9 0.91 8.5 25.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CCSAP PF15748.5 EKX37619.1 - 0.67 10.1 39.4 1.3 9.1 39.4 1.5 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated BUD22 PF09073.10 EKX37619.1 - 1.8 7.8 42.1 3.4 6.9 42.1 1.4 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 EKX37619.1 - 2.9 6.6 46.2 4.4 6.0 46.2 1.1 1 0 0 1 1 1 0 Presenilin Asp-B-Hydro_N PF05279.11 EKX37619.1 - 3 7.9 49.0 0.054 13.5 41.7 1.8 2 0 0 2 2 1 0 Aspartyl beta-hydroxylase N-terminal region AAA_11 PF13086.6 EKX37619.1 - 3.4 7.4 31.4 6.5 6.5 31.4 1.4 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.14 EKX37619.1 - 4.8 5.3 43.5 8 4.6 43.5 1.3 1 0 0 1 1 1 0 CDC45-like protein GREB1 PF15782.5 EKX37619.1 - 4.9 4.1 27.1 6.7 3.7 27.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Mid1 PF12929.7 EKX37621.1 - 9.7e-05 21.7 4.0 0.00018 20.9 4.0 1.3 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component DUF493 PF04359.14 EKX37622.1 - 1.5e-08 35.1 0.0 2.2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF493) Cwf_Cwc_15 PF04889.12 EKX37623.1 - 0.00092 19.0 6.5 0.00092 19.0 6.5 1.8 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 EKX37623.1 - 0.011 15.1 7.7 0.013 14.9 7.7 1.2 1 0 0 1 1 1 0 BUD22 MRFAP1 PF15155.6 EKX37623.1 - 0.058 13.9 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 MORF4 family-associated protein1 TT_ORF2 PF02957.15 EKX37623.1 - 0.6 11.0 7.3 1.8 9.5 7.3 1.8 1 0 0 1 1 1 0 TT viral ORF2 Roughex PF06020.11 EKX37623.1 - 1.5 7.9 8.6 1.9 7.5 8.6 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DNA_pol_phi PF04931.13 EKX37623.1 - 1.7 6.7 21.4 2.3 6.2 21.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 EKX37623.1 - 1.8 6.7 9.8 2.3 6.3 9.8 1.2 1 0 0 1 1 1 0 Nop14-like family SGT1 PF07093.11 EKX37623.1 - 2.2 6.6 7.3 3.1 6.1 7.3 1.1 1 0 0 1 1 1 0 SGT1 protein DUF2457 PF10446.9 EKX37623.1 - 4.2 6.4 20.7 0.13 11.4 14.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Myc_N PF01056.18 EKX37624.1 - 0.00015 21.8 1.4 0.00017 21.6 1.4 1.0 1 0 0 1 1 1 1 Myc amino-terminal region Sporozoite_P67 PF05642.11 EKX37624.1 - 0.0002 19.6 6.1 0.00023 19.5 6.1 1.0 1 0 0 1 1 1 1 Sporozoite P67 surface antigen SDA1 PF05285.12 EKX37624.1 - 0.0011 18.4 11.8 0.0012 18.4 11.8 1.1 1 0 0 1 1 1 1 SDA1 LAT PF15234.6 EKX37624.1 - 0.0023 17.7 7.7 0.0028 17.4 7.7 1.1 1 0 0 1 1 1 1 Linker for activation of T-cells Vfa1 PF08432.10 EKX37624.1 - 0.0078 16.6 3.6 0.009 16.4 3.6 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 EKX37624.1 - 0.01 14.2 12.6 0.011 14.1 12.6 1.0 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 EKX37624.1 - 0.012 14.1 13.2 0.014 13.9 13.2 1.0 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 EKX37624.1 - 0.018 13.3 16.3 0.02 13.2 16.3 1.0 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 EKX37624.1 - 0.025 14.4 6.9 0.03 14.1 6.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein BUD22 PF09073.10 EKX37624.1 - 0.055 12.8 13.0 0.06 12.7 13.0 1.1 1 0 0 1 1 1 0 BUD22 RPN2_C PF18004.1 EKX37624.1 - 0.059 13.3 3.7 0.067 13.1 3.7 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CPSF100_C PF13299.6 EKX37624.1 - 0.062 13.5 1.8 0.066 13.4 1.8 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Cwf_Cwc_15 PF04889.12 EKX37624.1 - 0.13 11.9 15.3 0.16 11.7 15.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_polI_A34 PF08208.11 EKX37624.1 - 0.15 12.2 5.6 0.18 11.9 5.6 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 GCIP PF13324.6 EKX37624.1 - 0.18 11.4 11.8 0.22 11.1 11.8 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF2457 PF10446.9 EKX37624.1 - 0.22 10.6 20.7 0.28 10.3 20.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RR_TM4-6 PF06459.12 EKX37624.1 - 0.22 11.3 5.6 0.24 11.2 5.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RRN3 PF05327.11 EKX37624.1 - 0.23 10.0 13.9 0.26 9.8 13.9 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PTPRCAP PF15713.5 EKX37624.1 - 0.27 11.5 14.7 0.4 11.0 14.7 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated YL1 PF05764.13 EKX37624.1 - 0.48 10.5 23.7 0.63 10.1 23.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein NOA36 PF06524.12 EKX37624.1 - 0.54 9.5 19.3 0.73 9.1 19.3 1.2 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 EKX37624.1 - 0.61 9.9 13.8 0.77 9.6 13.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF913 PF06025.12 EKX37624.1 - 0.73 8.7 3.9 0.74 8.7 3.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RNA_pol_Rpc4 PF05132.14 EKX37624.1 - 0.78 10.2 4.0 0.91 10.0 4.0 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Tub_N PF16322.5 EKX37624.1 - 0.81 10.1 12.9 1.1 9.7 12.9 1.1 1 0 0 1 1 1 0 Tubby N-terminal PPP4R2 PF09184.11 EKX37624.1 - 0.97 9.0 14.1 1.1 8.7 14.1 1.3 1 0 0 1 1 1 0 PPP4R2 DUF2722 PF10846.8 EKX37624.1 - 1 8.2 7.1 1.3 7.9 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CobT PF06213.12 EKX37624.1 - 1.3 8.3 19.4 1.6 8.0 19.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nucleo_P87 PF07267.11 EKX37624.1 - 1.4 7.7 5.7 1.5 7.6 5.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Presenilin PF01080.17 EKX37624.1 - 1.5 7.5 2.9 1.5 7.5 2.9 1.0 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 EKX37624.1 - 1.5 7.9 2.4 1.6 7.9 2.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Paf1 PF03985.13 EKX37624.1 - 1.7 7.5 16.7 2.1 7.2 16.7 1.1 1 0 0 1 1 1 0 Paf1 Merozoite_SPAM PF07133.11 EKX37624.1 - 1.8 8.5 25.0 2.3 8.2 25.0 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Pox_RNA_Pol_19 PF05320.12 EKX37624.1 - 2.2 8.3 14.0 3 7.8 14.0 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DNA_pol_phi PF04931.13 EKX37624.1 - 3.4 5.7 27.3 4.1 5.4 27.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi Astro_capsid_p PF12226.8 EKX37624.1 - 3.7 6.6 13.9 4 6.5 13.9 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein PI3K_1B_p101 PF10486.9 EKX37624.1 - 6.1 4.5 9.9 7.4 4.2 9.9 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TFB6 PF17110.5 EKX37624.1 - 6.3 6.5 9.1 8.4 6.1 9.1 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Laminin_G_3 PF13385.6 EKX37625.1 - 4.3e-15 56.2 0.0 2.6e-14 53.6 0.0 2.0 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 EKX37625.1 - 0.051 14.2 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Laminin G domain HLH PF00010.26 EKX37626.1 - 0.0002 21.2 0.3 0.00035 20.5 0.3 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PrmA PF06325.13 EKX37628.1 - 3.6e-11 43.0 0.0 5.3e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EKX37628.1 - 7.2e-09 36.2 0.0 2e-08 34.8 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX37628.1 - 5.9e-07 30.0 0.0 1.7e-06 28.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX37628.1 - 2.2e-06 27.6 0.0 4e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EKX37628.1 - 3.6e-06 26.1 0.1 5.2e-06 25.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 EKX37628.1 - 5.4e-06 26.4 0.0 8.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX37628.1 - 3.5e-05 23.7 0.0 6.7e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EKX37628.1 - 3.7e-05 23.6 0.1 5.7e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_12 PF08242.12 EKX37628.1 - 6.4e-05 23.6 0.0 0.00013 22.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 EKX37628.1 - 0.00016 21.6 0.0 0.0003 20.7 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase MTS PF05175.14 EKX37628.1 - 0.00022 20.8 0.0 0.00035 20.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EKX37628.1 - 0.0055 16.0 0.0 0.0072 15.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 EKX37628.1 - 0.0067 16.6 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 EKX37628.1 - 0.0091 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase TehB PF03848.14 EKX37628.1 - 0.013 14.9 0.3 0.036 13.5 0.3 1.8 1 1 0 1 1 1 0 Tellurite resistance protein TehB Cons_hypoth95 PF03602.15 EKX37628.1 - 0.033 13.8 0.0 0.055 13.1 0.0 1.4 1 1 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_32 PF13679.6 EKX37628.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 2 0 0 2 2 1 0 Methyltransferase domain HI0933_like PF03486.14 EKX37629.1 - 1.2e-82 277.8 0.4 2.5e-80 270.2 0.4 2.9 1 1 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 EKX37629.1 - 1.6e-06 27.7 0.0 7.9e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EKX37629.1 - 2.6e-06 26.8 1.7 0.00021 20.5 0.8 2.7 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.24 EKX37629.1 - 0.00012 21.7 0.3 0.0006 19.5 0.4 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EKX37629.1 - 0.00041 19.7 0.9 0.0031 16.8 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EKX37629.1 - 0.0023 18.1 0.3 0.0048 17.1 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EKX37629.1 - 0.0041 16.2 4.6 0.48 9.4 3.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EKX37629.1 - 0.0097 15.9 0.2 0.02 14.9 0.1 1.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EKX37629.1 - 0.016 14.0 1.3 0.025 13.4 1.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.17 EKX37629.1 - 0.023 13.9 1.6 4.6 6.4 0.3 2.6 3 0 0 3 3 3 0 Thi4 family Pyr_redox PF00070.27 EKX37629.1 - 0.037 14.6 2.1 0.79 10.3 1.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EKX37629.1 - 0.052 12.8 2.6 0.25 10.6 0.6 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EKX37629.1 - 0.054 12.7 0.2 0.11 11.7 0.2 1.5 1 1 0 1 1 1 0 FAD binding domain LysM PF01476.20 EKX37630.1 - 0.04 14.0 0.0 0.066 13.3 0.0 1.3 1 0 0 1 1 1 0 LysM domain Pkinase PF00069.25 EKX37631.1 - 2.1e-37 128.9 0.0 2.3e-37 128.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX37631.1 - 3.6e-23 82.2 0.0 4.2e-23 82.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX37631.1 - 5.8e-05 23.1 0.0 7.3e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX37631.1 - 0.011 15.0 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EKX37631.1 - 0.051 13.2 0.0 0.063 12.9 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 EKX37631.1 - 0.061 12.9 0.0 0.068 12.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 EKX37631.1 - 0.063 12.1 0.0 0.098 11.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 EKX37631.1 - 0.1 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 NETI PF14044.6 EKX37634.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 NETI protein SSP160 PF06933.11 EKX37636.1 - 0.2 9.8 7.5 0.25 9.5 7.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CDC45 PF02724.14 EKX37638.1 - 0.0013 17.1 18.7 0.0018 16.7 18.7 1.1 1 0 0 1 1 1 1 CDC45-like protein Merozoite_SPAM PF07133.11 EKX37638.1 - 0.014 15.4 33.8 0.024 14.6 33.8 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Paf1 PF03985.13 EKX37638.1 - 0.021 13.9 17.1 0.027 13.5 17.1 1.1 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.12 EKX37638.1 - 0.026 12.7 28.4 0.036 12.3 28.4 1.1 1 0 0 1 1 1 0 Nop14-like family CCDC106 PF15794.5 EKX37638.1 - 0.045 13.5 2.5 0.083 12.6 2.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 BUD22 PF09073.10 EKX37638.1 - 0.047 13.0 24.8 0.084 12.2 24.8 1.3 1 0 0 1 1 1 0 BUD22 RR_TM4-6 PF06459.12 EKX37638.1 - 0.052 13.4 10.0 0.077 12.8 10.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.12 EKX37638.1 - 0.068 12.6 30.3 0.11 12.0 30.3 1.2 1 0 0 1 1 1 0 SDA1 DUF913 PF06025.12 EKX37638.1 - 0.38 9.7 5.4 0.54 9.2 5.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 EKX37638.1 - 0.4 9.4 8.6 0.6 8.8 8.6 1.2 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 EKX37638.1 - 0.73 8.6 12.2 1 8.1 12.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CPSF100_C PF13299.6 EKX37638.1 - 1.4 9.1 7.0 2.8 8.1 6.3 1.9 2 0 0 2 2 1 0 Cleavage and polyadenylation factor 2 C-terminal SAPS PF04499.15 EKX37638.1 - 1.7 7.3 10.3 2.3 6.9 10.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PI3K_1B_p101 PF10486.9 EKX37638.1 - 1.8 6.2 5.0 2.5 5.8 5.0 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Hid1 PF12722.7 EKX37638.1 - 2 6.5 4.4 2.5 6.1 4.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RNA_pol_Rpc4 PF05132.14 EKX37638.1 - 2.2 8.7 8.3 4.8 7.6 8.3 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 CobT PF06213.12 EKX37638.1 - 2.3 7.5 30.5 4 6.7 30.5 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SpoIIIAH PF12685.7 EKX37638.1 - 3.1 7.6 12.6 4.9 6.9 12.6 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF4820 PF16091.5 EKX37638.1 - 4.8 6.5 7.9 7.8 5.8 7.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) LAP1C PF05609.12 EKX37638.1 - 5.4 6.0 11.2 7.6 5.5 11.2 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Vfa1 PF08432.10 EKX37638.1 - 5.6 7.3 13.8 11 6.3 13.8 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Mpp10 PF04006.12 EKX37638.1 - 8.1 4.8 33.7 0.083 11.3 25.9 1.5 2 0 0 2 2 2 0 Mpp10 protein UQ_con PF00179.26 EKX37639.1 - 5.1e-37 126.7 0.2 6.5e-37 126.3 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EKX37639.1 - 0.024 14.9 0.2 0.097 13.0 0.0 2.0 2 0 0 2 2 2 0 RWD domain CDC45 PF02724.14 EKX37639.1 - 0.12 10.6 4.7 0.13 10.6 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein ERM PF00769.19 EKX37640.1 - 2.5 7.8 23.9 4.4 7.0 23.9 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF5373 PF17343.2 EKX37640.1 - 4.8 7.0 8.7 9.5 6.0 8.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5373) FapA PF03961.13 EKX37640.1 - 5.4 5.5 5.3 8.8 4.8 5.3 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Roughex PF06020.11 EKX37640.1 - 8.9 5.3 11.7 3.2 6.8 6.3 2.3 2 0 0 2 2 2 0 Drosophila roughex protein Pkinase_Tyr PF07714.17 EKX37641.1 - 1.4e-32 113.1 0.0 1.6e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX37641.1 - 1.6e-27 96.5 0.0 3.8e-27 95.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 EKX37641.1 - 0.00052 18.9 0.0 0.00063 18.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX37641.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PfkB PF00294.24 EKX37642.1 - 5.1e-67 226.3 3.6 5.9e-67 226.1 3.6 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF5600 PF18150.1 EKX37643.1 - 0.0044 17.6 0.8 0.011 16.3 0.4 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF5600) FUSC PF04632.12 EKX37643.1 - 0.13 10.8 14.1 0.16 10.4 14.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF572 PF04502.13 EKX37643.1 - 0.34 10.5 18.6 0.45 10.1 18.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) TraY PF05509.11 EKX37643.1 - 2.2 8.4 7.6 13 6.0 1.1 3.1 3 0 0 3 3 3 0 TraY domain DUF87 PF01935.17 EKX37643.1 - 3.7 7.6 13.8 0.59 10.2 4.3 2.1 1 1 1 2 2 2 0 Helicase HerA, central domain BLOC1_2 PF10046.9 EKX37643.1 - 5.5 7.4 15.7 27 5.1 7.4 2.9 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 WD40 PF00400.32 EKX37644.1 - 2.3e-13 50.4 10.1 0.14 13.1 0.0 8.8 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX37644.1 - 2.2e-05 24.7 0.1 1.5 9.2 0.0 6.4 6 1 2 8 8 8 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EKX37644.1 - 0.031 12.9 0.1 10 4.6 0.0 2.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Alpha_kinase PF02816.18 EKX37645.1 - 8.8e-41 140.0 2.9 7.9e-34 117.4 0.2 2.6 1 1 1 2 2 2 2 Alpha-kinase family Sel1 PF08238.12 EKX37645.1 - 0.17 12.6 1.5 26 5.7 0.2 3.1 2 1 1 3 3 3 0 Sel1 repeat BRCA2 PF00634.18 EKX37647.1 - 1.3e-19 69.6 10.1 0.00094 18.8 0.1 4.3 4 0 0 4 4 4 4 BRCA2 repeat Cauli_VI PF01693.16 EKX37647.1 - 1.1e-05 25.6 0.2 34 4.9 0.0 4.6 4 0 0 4 4 4 4 Caulimovirus viroplasmin dUTPase PF00692.19 EKX37647.1 - 0.0056 16.4 0.0 27 4.4 0.0 4.0 4 0 0 4 4 4 1 dUTPase DUF5540 PF17694.1 EKX37647.1 - 3 8.4 11.0 15 6.2 0.2 4.4 5 0 0 5 5 5 0 Family of unknown function (DUF5540) DUF4333 PF14230.6 EKX37647.1 - 3.9 7.8 16.0 20 5.5 0.5 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4333) WD40 PF00400.32 EKX37648.1 - 3.6e-15 56.1 3.8 0.0018 19.1 0.1 7.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX37648.1 - 4.5e-12 46.1 0.0 0.18 12.1 0.0 5.4 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EKX37648.1 - 0.00029 19.5 0.0 0.04 12.5 0.0 2.3 2 0 0 2 2 2 2 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 EKX37648.1 - 0.00075 18.6 0.3 8.7 5.2 0.0 4.1 1 1 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EKX37648.1 - 0.0051 16.7 0.0 0.14 12.0 0.0 2.7 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.9 EKX37648.1 - 0.059 13.1 0.0 5.1 6.8 0.0 2.5 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain HrpB1_HrpK PF09613.10 EKX37648.1 - 0.14 11.8 0.1 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) PD40 PF07676.12 EKX37648.1 - 0.15 12.0 0.0 3.5 7.7 0.0 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat TIR_2 PF13676.6 EKX37649.1 - 1.9e-17 63.9 0.1 4.8e-16 59.4 0.0 2.8 2 0 0 2 2 2 1 TIR domain COR PF16095.5 EKX37649.1 - 1.1e-14 54.7 0.1 3e-14 53.3 0.1 1.7 2 0 0 2 2 2 1 C-terminal of Roc, COR, domain Roc PF08477.13 EKX37649.1 - 6.8e-14 52.1 0.0 2e-13 50.6 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EKX37649.1 - 1e-05 25.2 0.0 4.1e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 Ras family TIR PF01582.20 EKX37649.1 - 0.0015 18.4 0.0 0.0039 17.0 0.0 1.7 1 0 0 1 1 1 1 TIR domain Arf PF00025.21 EKX37649.1 - 0.0029 17.1 0.0 0.0079 15.7 0.0 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EKX37649.1 - 0.0036 17.4 0.0 0.021 14.9 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EKX37649.1 - 0.0092 15.4 0.0 0.029 13.7 0.0 1.9 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EKX37649.1 - 0.025 13.8 0.2 0.071 12.3 0.0 1.7 2 0 0 2 2 2 0 G-protein alpha subunit Surfac_D-trimer PF09006.11 EKX37649.1 - 0.086 12.7 0.0 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation NosL PF05573.12 EKX37649.1 - 0.12 12.7 1.4 12 6.3 0.1 3.2 3 0 0 3 3 3 0 NosL LRR_1 PF00560.33 EKX37649.1 - 2.4 9.1 4.2 82 4.4 0.1 3.6 3 0 0 3 3 2 0 Leucine Rich Repeat Myb_DNA-binding PF00249.31 EKX37650.1 - 1.2e-07 31.8 0.0 3.2e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain SBF PF01758.16 EKX37653.1 - 5.7e-17 62.0 14.2 1.4e-15 57.5 8.1 2.7 2 1 0 2 2 2 1 Sodium Bile acid symporter family PAP_central PF04928.17 EKX37654.1 - 3.1e-65 219.6 0.0 3.8e-65 219.3 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EKX37654.1 - 5.2e-07 29.4 0.0 1.9e-06 27.6 0.0 1.9 1 1 1 2 2 2 1 Poly(A) polymerase predicted RNA binding domain PAP_assoc PF03828.19 EKX37655.1 - 1.1e-18 67.1 0.1 3e-18 65.8 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase PAP_central PF04928.17 EKX37655.1 - 0.086 11.8 0.0 0.19 10.7 0.1 1.6 2 0 0 2 2 2 0 Poly(A) polymerase central domain Mitofilin PF09731.9 EKX37656.1 - 0.052 12.4 51.8 0.068 12.0 51.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF4778 PF16008.5 EKX37656.1 - 4.2 7.3 15.0 5.5 6.9 15.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Ank_2 PF12796.7 EKX37657.1 - 3.6e-25 88.4 3.2 5.5e-13 49.3 0.2 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX37657.1 - 2e-16 59.9 0.6 7.2e-08 32.6 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX37657.1 - 1.6e-13 50.4 0.6 0.0013 19.1 0.0 3.9 2 1 1 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EKX37657.1 - 4.1e-13 49.5 0.1 2.8e-06 27.8 0.1 2.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) RRM_1 PF00076.22 EKX37657.1 - 6.1e-12 45.2 0.0 7.2e-05 22.5 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_3 PF13606.6 EKX37657.1 - 3.6e-11 42.3 0.3 0.021 15.3 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat RRM_5 PF13893.6 EKX37657.1 - 0.0059 16.2 0.0 0.35 10.5 0.0 2.4 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 EKX37657.1 - 0.087 12.6 0.0 2.8 7.7 0.0 2.3 1 1 1 2 2 2 0 Rrp7 RRM-like N-terminal domain MFS_MOT1 PF16983.5 EKX37658.1 - 1.4e-51 173.5 21.1 7.3e-31 106.8 1.9 3.9 3 1 0 3 3 3 2 Molybdate transporter of MFS superfamily DUF3119 PF11317.8 EKX37658.1 - 0.25 11.6 1.3 0.69 10.2 1.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3119) SRCR PF00530.18 EKX37659.1 - 5.7e-79 261.0 53.6 1.8e-21 76.5 3.0 7.0 4 2 2 6 6 6 6 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 EKX37659.1 - 2.8e-07 31.0 22.4 0.027 15.0 1.1 4.8 4 1 1 5 5 5 4 Scavenger receptor cysteine-rich domain Ion_trans PF00520.31 EKX37660.1 - 3.8e-16 59.1 10.8 6e-16 58.4 10.8 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX37660.1 - 8.7e-08 32.0 1.1 8.7e-08 32.0 1.1 2.1 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 EKX37660.1 - 1.2e-06 28.4 0.0 9e-06 25.7 0.0 2.2 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain TRP PF06011.12 EKX37660.1 - 0.019 13.7 0.3 0.031 13.0 0.3 1.2 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel AAA_lid_9 PF17871.1 EKX37663.1 - 0.083 12.8 0.1 0.25 11.3 0.1 1.8 1 0 0 1 1 1 0 AAA lid domain Peptidase_C2 PF00648.21 EKX37665.1 - 1.1e-38 133.0 0.5 1.8e-27 96.2 0.0 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease SDA1 PF05285.12 EKX37665.1 - 0.037 13.5 14.6 0.047 13.1 14.6 1.1 1 0 0 1 1 1 0 SDA1 EABR PF12180.8 EKX37665.1 - 0.038 13.6 0.2 0.69 9.6 0.0 2.5 2 0 0 2 2 2 0 TSG101 and ALIX binding domain of CEP55 TFIIA PF03153.13 EKX37665.1 - 0.067 13.2 11.2 0.084 12.9 11.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 EKX37665.1 - 0.08 12.8 4.1 0.11 12.3 4.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PPP4R2 PF09184.11 EKX37665.1 - 0.084 12.5 13.6 0.12 11.9 13.6 1.3 1 0 0 1 1 1 0 PPP4R2 Pox_Ag35 PF03286.14 EKX37665.1 - 0.096 12.5 7.4 0.16 11.8 7.4 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RNA_pol_3_Rpc31 PF11705.8 EKX37665.1 - 0.16 12.2 19.0 0.28 11.4 19.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Sigma70_ner PF04546.13 EKX37665.1 - 0.17 11.7 11.3 0.32 10.8 11.3 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF4637 PF15470.6 EKX37665.1 - 0.21 11.3 11.6 0.4 10.4 11.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) RXT2_N PF08595.11 EKX37665.1 - 0.24 11.4 8.0 0.4 10.7 8.0 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.12 EKX37665.1 - 0.3 9.3 18.7 0.36 9.0 18.7 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 EKX37665.1 - 0.59 9.4 12.7 0.79 9.0 12.7 1.1 1 0 0 1 1 1 0 BUD22 TFB6 PF17110.5 EKX37665.1 - 0.67 9.7 7.6 1.2 8.9 7.6 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH HEV_ORF1 PF02444.16 EKX37665.1 - 0.71 10.5 4.2 1.3 9.6 4.2 1.3 1 0 0 1 1 1 0 Hepatitis E virus ORF-2 (Putative capsid protein) DUF2722 PF10846.8 EKX37665.1 - 0.78 8.6 5.6 1 8.2 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RPN2_C PF18004.1 EKX37665.1 - 1.7 8.6 9.0 2.8 7.8 9.0 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF913 PF06025.12 EKX37665.1 - 1.8 7.5 2.6 2.4 7.0 2.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DNA_pol_phi PF04931.13 EKX37665.1 - 2.6 6.0 25.8 3.5 5.6 25.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi RPA43_OB PF17875.1 EKX37665.1 - 2.9 8.5 7.3 5 7.8 7.3 1.4 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I CDC45 PF02724.14 EKX37665.1 - 2.9 6.1 16.4 3.9 5.6 16.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 EKX37665.1 - 3.3 6.8 23.8 5.3 6.1 23.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TRAP_alpha PF03896.16 EKX37665.1 - 3.5 6.7 11.3 5.2 6.2 11.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nucleo_P87 PF07267.11 EKX37665.1 - 3.9 6.2 11.2 5.1 5.8 11.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RRN3 PF05327.11 EKX37665.1 - 6.7 5.1 10.8 9.2 4.7 10.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RRM_occluded PF16842.5 EKX37666.1 - 1.8e-10 40.5 0.0 2.2e-05 24.2 0.0 3.4 3 1 0 3 3 3 2 Occluded RNA-recognition motif RRM_1 PF00076.22 EKX37666.1 - 1.7e-09 37.4 0.0 0.0013 18.5 0.0 4.1 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CENP-B_dimeris PF09026.10 EKX37666.1 - 5.1e-06 26.8 10.4 5.1e-06 26.8 10.4 4.3 4 1 1 5 5 3 2 Centromere protein B dimerisation domain DUF2457 PF10446.9 EKX37666.1 - 0.0047 16.1 30.4 0.0047 16.1 30.4 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF2457) Nop14 PF04147.12 EKX37666.1 - 0.0096 14.2 40.6 0.031 12.5 8.3 2.4 2 0 0 2 2 2 2 Nop14-like family CNDH2_C PF16858.5 EKX37666.1 - 0.012 15.5 16.0 0.033 14.1 5.4 2.6 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF2052 PF09747.9 EKX37666.1 - 0.084 13.0 36.7 0.053 13.6 7.4 2.9 3 1 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) CPSF100_C PF13299.6 EKX37666.1 - 0.16 12.1 10.9 2.1 8.5 3.0 2.6 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RRN3 PF05327.11 EKX37666.1 - 0.2 10.2 31.0 0.52 8.8 16.1 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 RR_TM4-6 PF06459.12 EKX37666.1 - 0.3 10.9 13.6 0.61 9.9 1.7 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DNA_pol_phi PF04931.13 EKX37666.1 - 0.65 8.0 61.7 0.67 8.0 17.1 2.2 2 0 0 2 2 2 0 DNA polymerase phi DUF913 PF06025.12 EKX37666.1 - 0.78 8.6 11.2 1.7 7.5 0.8 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Slu7 PF11708.8 EKX37666.1 - 0.97 9.1 32.8 1.8 8.3 13.7 3.2 3 0 0 3 3 3 0 Pre-mRNA splicing Prp18-interacting factor LAP1C PF05609.12 EKX37666.1 - 1.2 8.1 18.2 0.4 9.7 6.8 2.4 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Mpp10 PF04006.12 EKX37666.1 - 3.1 6.1 44.0 1.6 7.1 11.9 2.2 2 0 0 2 2 2 0 Mpp10 protein YL1 PF05764.13 EKX37666.1 - 3.8 7.5 53.9 0.21 11.6 10.7 3.2 3 0 0 3 3 3 0 YL1 nuclear protein CDC45 PF02724.14 EKX37666.1 - 4.1 5.6 41.6 1.1 7.4 12.6 3.0 3 0 0 3 3 3 0 CDC45-like protein Vfa1 PF08432.10 EKX37666.1 - 4.9 7.4 24.0 1.1 9.6 7.0 2.6 3 0 0 3 3 2 0 AAA-ATPase Vps4-associated protein 1 Drc1-Sld2 PF11719.8 EKX37666.1 - 4.9 6.6 26.3 0.91 9.0 5.4 2.3 2 0 0 2 2 2 0 DNA replication and checkpoint protein Tim54 PF11711.8 EKX37666.1 - 7.5 5.2 12.9 3.6 6.3 2.5 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 G-patch PF01585.23 EKX37667.1 - 0.046 13.6 0.1 0.15 12.0 0.1 1.9 1 1 0 1 1 1 0 G-patch domain HIG_1_N PF04588.13 EKX37668.1 - 2.4e-15 56.5 2.6 4.2e-15 55.7 2.6 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region MWFE PF15879.5 EKX37668.1 - 0.13 12.5 0.4 0.34 11.1 0.3 1.9 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit BetaGal_dom4_5 PF13364.6 EKX37672.1 - 0.097 13.2 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain NTP_transf_9 PF04248.12 EKX37673.1 - 0.003 17.4 0.0 0.0043 16.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF427) UBX PF00789.20 EKX37674.1 - 1.2e-09 38.2 0.0 2.2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.6 EKX37674.1 - 0.013 15.6 0.0 0.039 14.1 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like DUF3527 PF12043.8 EKX37674.1 - 0.019 14.5 0.2 0.019 14.5 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) Herpes_pp85 PF04637.12 EKX37674.1 - 0.31 9.4 1.2 0.46 8.8 1.2 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Methyltransf_16 PF10294.9 EKX37676.1 - 1.3e-06 28.2 0.5 0.00013 21.7 0.3 2.1 1 1 1 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 EKX37676.1 - 0.087 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EKX37676.1 - 0.097 13.4 0.1 7.5 7.4 0.1 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 EKX37676.1 - 0.17 12.6 0.2 1.2 9.8 0.2 2.2 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EKX37676.1 - 0.19 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Pkinase_Tyr PF07714.17 EKX37677.1 - 1.3e-44 152.5 0.0 1.5e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX37677.1 - 2.9e-44 151.4 0.0 3.5e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 EKX37677.1 - 1.1e-10 42.0 0.0 1.9e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX37677.1 - 1.6e-07 31.7 0.0 3.3e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX37677.1 - 1.1e-06 28.8 0.4 0.0012 19.2 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EKX37677.1 - 0.00022 21.5 0.1 0.0018 18.5 0.1 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX37677.1 - 0.00049 20.3 0.0 0.006 17.0 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat APH PF01636.23 EKX37677.1 - 0.0019 18.2 0.1 0.02 14.8 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX37677.1 - 0.02 13.7 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 EKX37677.1 - 0.28 10.2 0.0 0.42 9.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 EKX37678.1 - 1.6e-49 168.7 0.0 2.2e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX37678.1 - 6.2e-33 114.2 0.0 1e-32 113.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX37678.1 - 4.9e-09 35.5 0.1 6.3e-09 35.1 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EKX37678.1 - 1.5e-07 31.1 0.0 2.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EKX37678.1 - 5.9e-07 29.3 0.1 7.8e-07 28.9 0.1 1.1 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EKX37678.1 - 1.7e-06 27.5 0.1 2.5e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX37678.1 - 3.4e-05 23.9 0.1 0.00011 22.3 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 EKX37678.1 - 0.021 13.8 0.0 0.029 13.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 EKX37678.1 - 0.038 12.9 0.0 0.046 12.6 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Myb_DNA-binding PF00249.31 EKX37679.1 - 2.8e-05 24.2 0.1 0.00011 22.3 0.1 1.9 1 1 0 1 1 1 1 Myb-like DNA-binding domain Glyco_transf_5 PF08323.11 EKX37680.1 - 3.5e-55 187.4 0.0 5.1e-55 186.8 0.0 1.2 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EKX37680.1 - 7.2e-13 48.4 0.0 1.3e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Nic96 PF04097.14 EKX37681.1 - 1.3e-09 37.1 0.0 2e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Nup93/Nic96 HPP PF04982.13 EKX37682.1 - 0.00049 20.3 2.0 0.13 12.4 0.0 2.3 2 0 0 2 2 2 2 HPP family Nop14 PF04147.12 EKX37682.1 - 0.33 9.1 37.1 0.57 8.3 37.1 1.3 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 EKX37682.1 - 5.5 5.3 26.9 10 4.4 26.9 1.4 1 0 0 1 1 1 0 Mpp10 protein SAPS PF04499.15 EKX37682.1 - 6.7 5.4 8.3 0.21 10.4 2.1 1.6 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein CMD PF02627.20 EKX37684.1 - 8.8e-08 32.1 0.0 1.7e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family DMAP1 PF05499.12 EKX37684.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) YccV-like PF08755.11 EKX37686.1 - 2.7e-21 75.9 0.0 1.5e-20 73.5 0.0 2.4 2 1 0 2 2 2 1 Hemimethylated DNA-binding protein YccV like UVR PF02151.19 EKX37686.1 - 5.1e-08 32.4 29.7 0.041 13.6 3.0 5.2 5 0 0 5 5 5 4 UvrB/uvrC motif Fe_hyd_lg_C PF02906.14 EKX37686.1 - 0.39 10.4 2.1 0.91 9.1 0.9 2.1 2 0 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain RVT_N PF13655.6 EKX37686.1 - 0.57 10.5 0.1 0.57 10.5 0.1 2.9 4 0 0 4 4 4 0 N-terminal domain of reverse transcriptase LRR_8 PF13855.6 EKX37687.1 - 5.1e-59 195.9 102.4 1.4e-09 37.5 5.2 13.1 6 3 6 13 13 13 13 Leucine rich repeat LRR_4 PF12799.7 EKX37687.1 - 8.4e-54 178.6 103.5 1.5e-06 28.4 8.6 14.5 10 2 5 16 16 16 15 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX37687.1 - 7.5e-12 45.1 43.1 0.015 14.8 5.5 6.6 1 1 5 6 6 6 6 Leucine-rich repeat LRR_1 PF00560.33 EKX37687.1 - 4.3e-11 41.8 78.2 0.48 11.2 0.1 19.2 19 4 2 21 21 21 6 Leucine Rich Repeat LRR_5 PF13306.6 EKX37687.1 - 0.00056 19.9 2.6 2.7 8.0 0.1 4.2 2 1 0 4 4 4 2 BspA type Leucine rich repeat region (6 copies) ING PF12998.7 EKX37687.1 - 0.069 13.7 5.2 0.13 12.9 0.1 3.9 4 0 0 4 4 4 0 Inhibitor of growth proteins N-terminal histone-binding LRR_6 PF13516.6 EKX37687.1 - 0.37 11.0 0.1 0.37 11.0 0.1 19.3 22 0 0 22 22 22 0 Leucine Rich repeat CSTF_C PF14304.6 EKX37687.1 - 0.37 10.4 7.4 1.3 8.7 0.2 4.4 5 0 0 5 5 5 0 Transcription termination and cleavage factor C-terminal Pkinase PF00069.25 EKX37688.1 - 1.8e-11 43.9 0.0 2e-11 43.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX37688.1 - 3.9e-10 39.4 0.0 4.4e-10 39.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2889 PF11136.8 EKX37688.1 - 0.047 14.0 0.0 0.49 10.7 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2889) CMAS PF02353.20 EKX37689.1 - 1.3e-80 270.6 0.1 1.9e-80 270.1 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Amino_oxidase PF01593.24 EKX37689.1 - 1.2e-16 61.1 0.3 8.2e-13 48.4 0.0 2.8 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EKX37689.1 - 1.3e-16 60.6 0.0 3.8e-16 59.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Methyltransf_25 PF13649.6 EKX37689.1 - 2.3e-12 47.5 0.0 8.1e-12 45.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX37689.1 - 2e-10 41.1 0.0 7.6e-10 39.3 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX37689.1 - 6.1e-08 32.6 0.0 1.3e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DAO PF01266.24 EKX37689.1 - 5.8e-06 26.1 0.5 1.7e-05 24.6 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Methyltransf_12 PF08242.12 EKX37689.1 - 8.2e-06 26.5 0.0 4.1e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain FAD_binding_2 PF00890.24 EKX37689.1 - 4.3e-05 22.8 0.0 6.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EKX37689.1 - 0.0001 21.7 0.2 0.00081 18.7 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EKX37689.1 - 0.00017 21.0 0.0 0.00026 20.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EKX37689.1 - 0.0036 16.4 0.0 0.0068 15.5 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A TPMT PF05724.11 EKX37689.1 - 0.0079 15.9 0.0 0.026 14.2 0.0 1.8 2 0 0 2 2 1 1 Thiopurine S-methyltransferase (TPMT) AlaDh_PNT_C PF01262.21 EKX37689.1 - 0.0094 15.3 0.0 0.04 13.2 0.0 2.0 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EKX37689.1 - 0.014 14.6 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family PCMT PF01135.19 EKX37689.1 - 0.017 14.9 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pyr_redox PF00070.27 EKX37689.1 - 0.022 15.3 0.0 0.089 13.4 0.0 2.0 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EKX37689.1 - 0.027 13.2 0.0 0.049 12.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein ECF_trnsprt PF12822.7 EKX37689.1 - 0.07 13.2 1.6 0.16 12.1 1.6 1.5 1 0 0 1 1 1 0 ECF transporter, substrate-specific component FtsJ PF01728.19 EKX37689.1 - 0.076 13.1 0.0 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_15 PF09445.10 EKX37689.1 - 0.079 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MTS PF05175.14 EKX37689.1 - 0.13 11.8 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain ADH_zinc_N PF00107.26 EKX37689.1 - 0.18 11.8 0.0 1.8 8.5 0.0 2.4 2 1 0 2 2 2 0 Zinc-binding dehydrogenase NAD_binding_9 PF13454.6 EKX37689.1 - 0.2 11.6 0.3 22 5.0 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 EKX37689.1 - 0.2 11.5 0.1 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF5134 PF17197.4 EKX37690.1 - 0.014 15.3 0.2 0.017 15.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) HCO3_cotransp PF00955.21 EKX37691.1 - 4.9e-88 296.2 5.2 9.2e-48 163.3 0.2 2.0 1 1 0 2 2 2 2 HCO3- transporter family JmjC PF02373.22 EKX37692.1 - 2.6e-38 131.0 0.0 3.8e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase Ephrin_rec_like PF07699.13 EKX37693.1 - 0.00086 19.0 4.5 0.00086 19.0 4.5 2.3 1 1 1 2 2 2 1 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX37693.1 - 0.49 10.8 15.6 0.31 11.5 12.9 2.1 1 1 1 2 2 2 0 TNFR/NGFR cysteine-rich region Cep57_CLD PF14073.6 EKX37694.1 - 0.00025 21.1 15.2 0.00025 21.1 15.2 2.2 2 0 0 2 2 2 1 Centrosome localisation domain of Cep57 DUF4407 PF14362.6 EKX37694.1 - 0.0003 20.3 7.1 0.00046 19.6 7.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) GAS PF13851.6 EKX37694.1 - 0.002 17.5 32.2 0.0093 15.3 7.5 2.6 2 1 0 2 2 2 2 Growth-arrest specific micro-tubule binding YabA PF06156.13 EKX37694.1 - 0.0074 16.9 6.2 0.0074 16.9 6.2 3.3 2 1 1 3 3 3 1 Initiation control protein YabA ZnuA PF01297.17 EKX37694.1 - 0.0099 15.3 3.8 0.02 14.3 3.7 1.4 1 1 0 1 1 1 1 Zinc-uptake complex component A periplasmic Fez1 PF06818.15 EKX37694.1 - 0.076 13.5 30.9 0.33 11.4 14.1 2.2 1 1 1 2 2 2 0 Fez1 V_ATPase_I PF01496.19 EKX37694.1 - 0.087 10.7 21.1 0.0058 14.6 7.4 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF3450 PF11932.8 EKX37694.1 - 0.23 10.7 22.4 0.12 11.7 10.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF2203 PF09969.9 EKX37694.1 - 0.34 11.6 16.5 1.1 10.0 3.9 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Fmp27_WPPW PF10359.9 EKX37694.1 - 0.35 9.7 24.3 0.053 12.4 8.4 2.1 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain HOOK PF05622.12 EKX37694.1 - 0.36 8.9 28.7 0.49 8.5 11.5 2.2 2 0 0 2 2 2 0 HOOK protein BLOC1_2 PF10046.9 EKX37694.1 - 0.44 10.9 21.0 0.97 9.8 1.6 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 VASP_tetra PF08776.11 EKX37694.1 - 0.62 9.7 10.3 2.7 7.7 0.9 3.6 3 0 0 3 3 3 0 VASP tetramerisation domain TMPIT PF07851.13 EKX37694.1 - 0.63 9.2 20.0 0.83 8.8 5.1 2.3 2 1 0 2 2 2 0 TMPIT-like protein NPV_P10 PF05531.12 EKX37694.1 - 0.85 10.1 11.2 1.5 9.3 1.3 2.8 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein DUF4446 PF14584.6 EKX37694.1 - 1.5 8.8 14.5 2.5 8.1 1.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) Baculo_PEP_C PF04513.12 EKX37694.1 - 1.8 8.6 11.2 1.8 8.6 2.6 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spectrin PF00435.21 EKX37694.1 - 2.2 8.8 24.5 3.2 8.3 4.0 2.8 2 1 0 2 2 2 0 Spectrin repeat DUF4665 PF15679.5 EKX37694.1 - 2.3 8.9 11.6 0.23 12.1 4.8 2.6 2 2 0 2 2 2 0 Domain of unknown function (DUF4665) ApoO PF09769.9 EKX37694.1 - 2.5 8.1 4.0 1.8 8.6 0.6 2.2 2 0 0 2 2 2 0 Apolipoprotein O SKA2 PF16740.5 EKX37694.1 - 3.5 7.4 23.5 0.26 11.1 13.7 3.2 2 2 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF4200 PF13863.6 EKX37694.1 - 3.5 8.0 29.9 0.08 13.3 8.9 3.4 2 2 1 3 3 3 0 Domain of unknown function (DUF4200) FliD_N PF02465.18 EKX37694.1 - 3.6 8.4 10.7 8.4 7.2 2.3 2.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Fib_alpha PF08702.10 EKX37694.1 - 4 7.6 25.1 1.6 8.9 6.4 3.4 2 2 2 4 4 4 0 Fibrinogen alpha/beta chain family Occludin_ELL PF07303.13 EKX37694.1 - 4.2 8.2 13.8 5.9 7.7 3.4 2.8 2 1 0 2 2 2 0 Occludin homology domain FapA PF03961.13 EKX37694.1 - 5.4 5.5 19.0 0.65 8.5 6.9 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A zf-C4H2 PF10146.9 EKX37694.1 - 5.7 7.2 21.9 1 9.7 5.8 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein CENP-F_leu_zip PF10473.9 EKX37694.1 - 6.2 6.8 41.8 1 9.4 21.7 2.9 2 2 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_2 PF01920.20 EKX37694.1 - 6.9 6.7 32.3 0.86 9.6 2.9 4.2 2 2 2 4 4 4 0 Prefoldin subunit Jnk-SapK_ap_N PF09744.9 EKX37694.1 - 7.4 6.8 34.7 11 6.3 15.8 2.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 ERM PF00769.19 EKX37694.1 - 7.6 6.3 33.2 0.26 11.1 14.5 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family OmpH PF03938.14 EKX37694.1 - 8.6 6.7 26.7 4.4 7.6 4.0 2.7 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF5082 PF16888.5 EKX37695.1 - 0.00067 19.9 10.2 0.0013 19.0 10.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) Laminin_II PF06009.12 EKX37695.1 - 0.0081 16.2 5.2 0.0081 16.2 5.2 2.3 1 1 1 2 2 2 1 Laminin Domain II Spc24 PF08286.11 EKX37695.1 - 0.11 12.8 9.2 1.3 9.3 1.8 2.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF1319 PF07028.11 EKX37695.1 - 0.31 11.3 5.7 0.64 10.3 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) Seryl_tRNA_N PF02403.22 EKX37695.1 - 0.35 11.1 14.7 0.042 14.1 6.8 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CorA PF01544.18 EKX37695.1 - 0.41 9.9 7.1 0.72 9.1 7.1 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2508 PF10704.9 EKX37695.1 - 0.7 10.1 6.4 0.47 10.7 3.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2508) EF-hand_1 PF00036.32 EKX37696.1 - 2.1e-18 64.4 9.2 3.6e-06 26.1 0.3 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EKX37696.1 - 8.8e-15 53.3 2.2 0.00013 21.6 0.2 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 EKX37696.1 - 8.9e-15 54.9 7.1 6.8e-07 29.6 2.4 3.6 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EKX37696.1 - 5.6e-14 50.9 9.4 0.00026 20.3 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EKX37696.1 - 5.4e-13 48.6 10.1 2e-05 24.3 0.4 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 EKX37696.1 - 7.8e-07 29.0 4.0 0.0088 16.0 0.0 3.3 3 1 1 4 4 4 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EKX37696.1 - 0.0073 16.6 2.0 0.71 10.2 0.5 2.8 2 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 EKX37696.1 - 0.015 15.1 3.8 0.026 14.4 0.0 2.9 4 0 0 4 4 4 0 EF hand DUF3911 PF13050.6 EKX37696.1 - 0.056 13.6 2.8 3.7 7.7 0.3 3.0 2 2 1 3 3 3 0 Protein of unknown function (DUF3911) DUF1707 PF08044.11 EKX37696.1 - 0.18 11.9 0.0 1.7 8.8 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1707) Rubredoxin_2 PF18073.1 EKX37696.1 - 0.84 9.4 4.9 1.3 8.8 4.9 1.3 1 0 0 1 1 1 0 Rubredoxin metal binding domain EF-hand_1 PF00036.32 EKX37697.1 - 1.4e-18 65.0 10.4 3e-06 26.4 0.3 3.7 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EKX37697.1 - 4.4e-15 55.9 9.6 1.2e-08 35.3 1.2 3.3 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX37697.1 - 1.7e-13 49.3 4.9 0.00026 20.7 0.4 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EKX37697.1 - 1.9e-13 49.2 8.4 0.00021 20.6 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EKX37697.1 - 4.8e-13 48.7 7.1 1.7e-06 27.8 0.1 3.7 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 EKX37697.1 - 4.3e-07 29.8 1.0 0.0039 17.1 0.0 2.8 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EKX37697.1 - 0.0032 17.8 2.5 0.35 11.2 0.3 3.1 1 1 2 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region SHOCT PF09851.9 EKX37697.1 - 0.094 12.5 0.6 17 5.3 0.1 3.1 3 0 0 3 3 3 0 Short C-terminal domain EF-hand_10 PF14788.6 EKX37697.1 - 0.39 10.6 0.1 0.39 10.6 0.1 2.8 4 0 0 4 4 4 0 EF hand Fez1 PF06818.15 EKX37699.1 - 0.05 14.1 78.7 0.45 10.9 33.3 4.3 1 1 2 3 3 3 0 Fez1 APG6_N PF17675.1 EKX37699.1 - 0.081 13.5 90.1 3.1 8.3 11.6 5.9 1 1 5 6 6 6 0 Apg6 coiled-coil region Ehrlichia_rpt PF09528.10 EKX37699.1 - 0.11 12.0 0.2 0.11 12.0 0.2 2.4 2 0 0 2 2 2 0 Ehrlichia tandem repeat (Ehrlichia_rpt) DUF1664 PF07889.12 EKX37699.1 - 0.34 11.0 65.9 1.4 8.9 7.8 6.2 1 1 6 7 7 7 0 Protein of unknown function (DUF1664) ERM PF00769.19 EKX37699.1 - 1.5 8.6 90.1 6.4 6.5 32.3 4.3 1 1 3 4 4 4 0 Ezrin/radixin/moesin family Tropomyosin_1 PF12718.7 EKX37699.1 - 5.7 7.1 85.5 0.17 12.0 8.1 6.3 1 1 5 6 6 6 0 Tropomyosin like ADIP PF11559.8 EKX37699.1 - 7.4 6.7 84.5 0.087 12.9 8.0 6.0 1 1 5 6 6 6 0 Afadin- and alpha -actinin-Binding zf-C2H2_aberr PF17017.5 EKX37700.1 - 0.19 11.9 0.4 0.35 11.0 0.1 1.6 1 1 1 2 2 2 0 Aberrant zinc-finger OAM_dimer PF16554.5 EKX37701.1 - 0.16 12.4 0.1 0.3 11.6 0.1 1.4 1 0 0 1 1 1 0 Dimerisation domain of d-ornithine 4,5-aminomutase Gp-FAR-1 PF05823.12 EKX37702.1 - 0.097 13.0 0.6 0.16 12.4 0.6 1.3 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) N_formyltrans_C PF18216.1 EKX37702.1 - 0.2 11.4 0.0 16 5.3 0.0 3.3 4 0 0 4 4 4 0 N-formyltransferase dimerization C-terminal domain Homeobox_KN PF05920.11 EKX37703.1 - 4.4e-10 39.3 5.7 4.1e-09 36.2 3.0 2.8 2 1 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 EKX37703.1 - 0.68 9.8 8.7 6.8 6.6 3.1 2.3 2 0 0 2 2 2 0 Homeodomain YGGT PF02325.17 EKX37704.1 - 1.8e-16 60.3 1.0 2.7e-16 59.8 1.0 1.3 1 0 0 1 1 1 1 YGGT family Pyr_redox_2 PF07992.14 EKX37705.1 - 3.1e-31 108.7 2.4 8.2e-17 61.4 1.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EKX37705.1 - 5e-25 87.9 0.3 1.1e-24 86.8 0.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GIDA PF01134.22 EKX37705.1 - 7.7e-08 31.8 4.7 7.7e-07 28.5 1.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EKX37705.1 - 1e-07 31.4 3.2 0.0022 17.2 1.1 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 EKX37705.1 - 0.0017 17.8 1.4 0.0024 17.3 1.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase PTS_IIB PF02302.17 EKX37705.1 - 0.07 13.8 0.2 7.4 7.3 0.0 3.2 3 0 0 3 3 3 0 PTS system, Lactose/Cellobiose specific IIB subunit Helicase_C PF00271.31 EKX37706.1 - 2.5e-14 53.6 0.3 8e-14 51.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EKX37706.1 - 3.3e-08 33.5 0.1 2.2e-07 30.8 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EKX37706.1 - 0.00017 21.4 0.0 0.00059 19.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EKX37706.1 - 0.00038 20.8 0.1 0.0011 19.3 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EKX37706.1 - 0.0018 18.6 0.1 0.0018 18.6 0.1 2.6 3 1 0 3 3 3 1 AAA domain T2SSE PF00437.20 EKX37706.1 - 0.011 14.8 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 EKX37706.1 - 0.018 14.5 0.0 0.045 13.2 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein PWI PF01480.17 EKX37706.1 - 0.018 15.3 0.0 0.1 12.9 0.0 2.4 2 0 0 2 2 1 0 PWI domain ATPase PF06745.13 EKX37706.1 - 0.058 12.7 0.0 0.058 12.7 0.0 2.3 3 0 0 3 3 3 0 KaiC AAA_29 PF13555.6 EKX37706.1 - 0.21 11.4 0.0 0.51 10.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EKX37706.1 - 0.25 11.8 0.0 0.25 11.8 0.0 3.4 4 0 0 4 4 4 0 ABC transporter FtsK_SpoIIIE PF01580.18 EKX37706.1 - 1.2 8.4 0.0 1.2 8.4 0.0 3.1 3 1 1 4 4 4 0 FtsK/SpoIIIE family SRP54 PF00448.22 EKX37706.1 - 9 5.9 7.7 1.4 8.5 0.0 3.0 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain DUF3431 PF11913.8 EKX37708.1 - 8.5e-18 64.9 0.1 2e-09 37.6 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3431) DUF3587 PF12132.8 EKX37708.1 - 0.0017 17.8 0.1 0.0029 17.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3587) ABC_tran PF00005.27 EKX37710.1 - 1.5e-25 90.3 0.7 3.8e-24 85.8 0.1 2.8 2 1 1 3 3 3 1 ABC transporter ABC_tran_Xtn PF12848.7 EKX37710.1 - 1e-22 80.0 3.0 1e-22 80.0 3.0 2.6 3 0 0 3 3 3 1 ABC transporter ABC_tran_CTD PF16326.5 EKX37710.1 - 7.8e-12 45.3 3.1 7.8e-12 45.3 3.1 3.4 3 0 0 3 3 3 1 ABC transporter C-terminal domain AAA_21 PF13304.6 EKX37710.1 - 7e-10 39.2 0.2 0.00059 19.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EKX37710.1 - 7.2e-06 25.6 0.1 2.2e-05 24.0 0.1 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 EKX37710.1 - 0.00061 20.1 0.4 0.00061 20.1 0.4 2.1 3 1 0 3 3 2 1 AAA domain Dynamin_N PF00350.23 EKX37710.1 - 0.00098 19.2 0.7 0.011 15.8 0.0 2.5 1 1 1 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EKX37710.1 - 0.001 19.1 0.1 0.0036 17.4 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase MeaB PF03308.16 EKX37710.1 - 0.0025 16.8 0.6 0.0094 15.0 0.1 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP-synt_ab PF00006.25 EKX37710.1 - 0.0041 16.8 0.2 0.0078 15.9 0.2 1.4 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.6 EKX37710.1 - 0.0068 16.1 0.1 0.016 15.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain TolA_bind_tri PF16331.5 EKX37710.1 - 0.0078 16.3 2.5 0.047 13.8 0.2 2.5 2 0 0 2 2 2 1 TolA binding protein trimerisation AAA_30 PF13604.6 EKX37710.1 - 0.049 13.4 2.8 1.5 8.5 2.8 2.4 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EKX37710.1 - 0.054 14.0 0.0 0.054 14.0 0.0 3.2 3 1 0 3 3 1 0 AAA domain cobW PF02492.19 EKX37710.1 - 0.057 13.0 0.1 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 EKX37710.1 - 0.064 12.4 0.0 0.2 10.8 0.0 1.8 1 1 0 1 1 1 0 NB-ARC domain DUF16 PF01519.16 EKX37710.1 - 0.081 13.4 8.7 2.4 8.7 0.6 2.9 3 0 0 3 3 3 0 Protein of unknown function DUF16 DUF2312 PF10073.9 EKX37710.1 - 0.09 12.4 2.1 0.59 9.8 1.6 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) AAA_27 PF13514.6 EKX37710.1 - 0.19 11.3 0.0 0.19 11.3 0.0 3.1 4 0 0 4 4 3 0 AAA domain AAA_15 PF13175.6 EKX37710.1 - 0.59 9.8 5.6 1.2 8.8 0.1 3.1 3 1 0 3 3 3 0 AAA ATPase domain SYCE1 PF15233.6 EKX37710.1 - 1.5 8.8 7.7 0.2 11.7 2.1 2.3 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 BLOC1_2 PF10046.9 EKX37710.1 - 2.2 8.6 6.3 1.1 9.6 0.3 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LPP PF04728.13 EKX37710.1 - 2.3 8.7 5.6 1.7 9.1 0.8 3.2 2 1 0 2 2 2 0 Lipoprotein leucine-zipper BAR PF03114.18 EKX37710.1 - 2.5 7.7 9.7 0.096 12.3 0.5 2.8 3 0 0 3 3 3 0 BAR domain AAA_33 PF13671.6 EKX37710.1 - 2.7 8.1 5.2 1.1 9.4 0.8 2.8 3 1 0 3 3 3 0 AAA domain FlaC_arch PF05377.11 EKX37710.1 - 6.5 7.2 5.2 4.1 7.9 0.5 3.1 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF4315 PF14193.6 EKX37710.1 - 7.9 6.6 10.3 1.2 9.2 0.5 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4315) ASH PF15780.5 EKX37711.1 - 8.9e-30 102.8 8.6 0.0011 19.1 0.0 14.3 15 0 0 15 15 15 6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 EKX37711.1 - 2.8e-11 43.2 4.0 0.12 12.2 0.1 7.3 8 0 0 8 8 8 4 MSP (Major sperm protein) domain CH PF00307.31 EKX37711.1 - 1.7e-06 28.1 0.0 2.5e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 Calponin homology (CH) domain DUF1573 PF07610.11 EKX37711.1 - 7e-05 22.8 1.5 2.5 8.2 0.1 7.4 10 0 0 10 10 10 1 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 EKX37711.1 - 0.00026 21.2 8.1 5.6 7.3 0.0 8.6 11 0 0 11 11 11 1 Transmembrane protein 131-like PapD-like PF14874.6 EKX37711.1 - 0.00036 20.6 2.7 1.9 8.7 0.0 5.7 5 1 0 5 5 5 1 Flagellar-associated PapD-like Transglut_C PF00927.22 EKX37711.1 - 0.047 13.8 0.2 2.2 8.5 0.0 4.0 4 0 0 4 4 4 0 Transglutaminase family, C-terminal ig like domain fn3_5 PF06280.12 EKX37711.1 - 0.33 11.6 1.8 1.2e+02 3.4 0.1 4.9 4 1 0 4 4 4 0 Fn3-like domain Pkinase PF00069.25 EKX37712.1 - 3.6e-40 138.0 0.3 2.9e-39 135.0 0.2 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX37712.1 - 5.1e-22 78.4 0.0 7.2e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX37712.1 - 0.0032 16.3 0.1 0.0062 15.4 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EKX37712.1 - 0.0062 15.6 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 EKX37712.1 - 0.016 14.5 0.1 0.037 13.3 0.0 1.5 2 0 0 2 2 2 0 Kinase-like IBB PF01749.20 EKX37712.1 - 0.017 15.5 0.1 9.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Importin beta binding domain APH PF01636.23 EKX37712.1 - 0.046 13.6 0.0 0.41 10.5 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family ComGF PF15980.5 EKX37712.1 - 0.18 12.2 0.7 0.38 11.2 0.7 1.5 1 0 0 1 1 1 0 Putative Competence protein ComGF Methyltransf_31 PF13847.6 EKX37714.1 - 0.031 14.1 0.0 0.11 12.3 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain Ion_trans PF00520.31 EKX37715.1 - 1.5e-35 122.6 20.2 3.7e-35 121.3 20.6 1.4 2 0 0 2 2 2 1 Ion transport protein PKD_channel PF08016.12 EKX37715.1 - 4.5e-06 25.6 14.1 8e-06 24.8 14.1 1.3 1 1 0 1 1 1 1 Polycystin cation channel EF-hand_1 PF00036.32 EKX37715.1 - 0.013 15.0 0.6 0.11 12.1 0.0 2.6 2 0 0 2 2 2 0 EF hand DUF2207 PF09972.9 EKX37715.1 - 0.073 11.8 3.4 1.9 7.2 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) EF-hand_6 PF13405.6 EKX37715.1 - 0.075 13.0 0.0 0.27 11.3 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain Lig_chan PF00060.26 EKX37715.1 - 0.17 11.7 3.1 0.95 9.3 0.8 2.2 2 0 0 2 2 2 0 Ligand-gated ion channel eIF-5_eIF-2B PF01873.17 EKX37716.1 - 2.3e-34 117.8 0.5 3.1e-34 117.3 0.5 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 DUF4413 PF14372.6 EKX37716.1 - 0.0053 17.1 0.0 0.01 16.2 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4413) Herpes_US12 PF05363.12 EKX37716.1 - 0.42 11.4 1.9 0.52 11.1 0.1 2.0 2 0 0 2 2 2 0 Herpesvirus US12 family bZIP_1 PF00170.21 EKX37717.1 - 0.013 15.6 9.6 0.45 10.7 1.6 3.2 2 1 1 3 3 3 0 bZIP transcription factor Filament PF00038.21 EKX37717.1 - 0.031 13.8 11.2 0.067 12.8 10.6 1.7 1 1 0 1 1 1 0 Intermediate filament protein GldM_N PF12081.8 EKX37717.1 - 0.19 11.8 8.1 0.92 9.6 8.9 1.7 2 0 0 2 2 2 0 GldM N-terminal domain CENP-H PF05837.12 EKX37717.1 - 0.34 11.3 12.5 1.4 9.3 0.3 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) TPR_MLP1_2 PF07926.12 EKX37717.1 - 0.42 10.7 13.7 0.17 12.0 2.8 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 EKX37717.1 - 0.66 9.0 5.2 1.1 8.2 5.2 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cnn_1N PF07989.11 EKX37717.1 - 0.67 10.2 13.7 0.84 9.8 1.2 3.1 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 TACC_C PF05010.14 EKX37717.1 - 0.85 9.4 14.7 1.1 9.0 12.3 1.9 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal BST2 PF16716.5 EKX37717.1 - 0.89 10.2 12.1 0.19 12.3 0.5 3.0 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 FAM76 PF16046.5 EKX37717.1 - 1.1 8.6 6.6 1.4 8.2 6.6 1.1 1 0 0 1 1 1 0 FAM76 protein Jnk-SapK_ap_N PF09744.9 EKX37717.1 - 1.2 9.4 13.8 1.9 8.7 13.8 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 TBCA PF02970.16 EKX37717.1 - 1.4 9.3 14.1 7.8 6.9 4.7 2.4 1 1 1 2 2 2 0 Tubulin binding cofactor A PRKG1_interact PF15898.5 EKX37717.1 - 1.5 9.8 9.7 6.3 7.8 9.7 2.0 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain ZapB PF06005.12 EKX37717.1 - 3.1 8.3 14.7 4.3e+02 1.5 14.7 2.6 1 1 0 1 1 1 0 Cell division protein ZapB Ribosomal_L29 PF00831.23 EKX37717.1 - 3.4 7.7 7.9 1.8 8.6 0.4 3.1 2 1 1 3 3 3 0 Ribosomal L29 protein DivIVA PF05103.13 EKX37717.1 - 3.4 7.8 13.5 42 4.2 13.5 2.7 1 1 0 1 1 1 0 DivIVA protein TSC22 PF01166.18 EKX37717.1 - 3.6 8.0 8.4 2.8 8.3 1.4 2.9 1 1 1 2 2 2 0 TSC-22/dip/bun family Glycos_transf_1 PF00534.20 EKX37718.1 - 5.5e-11 42.3 0.0 1.3e-10 41.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EKX37718.1 - 2.2e-08 34.6 0.0 3.8e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Chorion_S16 PF05836.12 EKX37718.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Chorion protein S16 HAT PF02184.16 EKX37719.1 - 1.9e-25 88.5 62.1 1.5e-11 44.0 0.7 15.1 16 0 0 16 16 16 4 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 EKX37719.1 - 5.1e-25 86.0 31.1 0.00049 20.7 0.2 12.4 6 4 7 13 13 12 9 Tetratricopeptide repeat TPR_19 PF14559.6 EKX37719.1 - 7.8e-17 61.6 3.8 0.094 13.2 0.0 8.0 6 2 1 8 8 7 4 Tetratricopeptide repeat Suf PF05843.14 EKX37719.1 - 3.9e-16 59.9 24.5 1.3e-05 25.3 1.1 5.7 2 2 3 5 5 5 4 Suppressor of forked protein (Suf) TPR_2 PF07719.17 EKX37719.1 - 5e-13 48.1 7.7 2.9 8.2 0.0 10.1 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX37719.1 - 7.6e-13 47.9 3.2 0.021 15.2 0.0 7.3 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX37719.1 - 6.9e-12 45.8 17.4 0.0089 16.7 0.0 7.8 6 3 2 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX37719.1 - 1.3e-09 37.5 5.2 0.89 9.9 0.0 8.2 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX37719.1 - 2.5e-05 23.8 1.1 0.85 9.4 0.0 5.4 6 0 0 6 6 6 1 TPR repeat Mad3_BUB1_I PF08311.12 EKX37719.1 - 2.9e-05 24.0 21.6 0.25 11.3 2.9 6.5 5 2 0 5 5 5 2 Mad3/BUB1 homology region 1 Wzy_C_2 PF11846.8 EKX37719.1 - 3.4e-05 23.8 2.7 0.0031 17.5 0.1 3.1 2 1 1 3 3 3 1 Virulence factor membrane-bound polymerase, C-terminal TPR_6 PF13174.6 EKX37719.1 - 0.00031 21.2 22.9 9.3 7.1 0.0 10.1 11 2 1 12 12 11 1 Tetratricopeptide repeat NRDE-2 PF08424.10 EKX37719.1 - 0.00039 19.7 17.7 0.13 11.4 1.2 5.7 2 2 0 3 3 3 2 NRDE-2, necessary for RNA interference TPR_9 PF13371.6 EKX37719.1 - 0.00086 19.4 9.6 1.4 9.1 0.3 6.6 5 2 1 6 6 6 1 Tetratricopeptide repeat SNAP PF14938.6 EKX37719.1 - 0.015 14.8 0.2 3.7 6.9 0.0 3.6 2 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP SUKH-3 PF14433.6 EKX37719.1 - 0.081 13.4 2.3 0.38 11.2 0.0 2.9 3 1 0 3 3 2 0 SUKH-3 immunity protein TPR_12 PF13424.6 EKX37719.1 - 0.11 12.8 13.1 49 4.3 0.0 8.1 7 2 1 8 8 8 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 EKX37719.1 - 2.5 8.2 15.3 28 4.9 0.1 6.0 5 2 2 7 7 6 0 U3 small nucleolar RNA-associated protein 6 DUF1823 PF08853.11 EKX37720.1 - 8.7e-39 132.2 0.0 1.3e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1823) Rv2175c_C PF18367.1 EKX37720.1 - 0.077 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Rv2175c C-terminal domain of unknown function DUF5486 PF17588.2 EKX37722.1 - 0.022 14.6 0.0 2.7 7.9 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5486) His_Phos_1 PF00300.22 EKX37724.1 - 8.3e-34 117.0 0.0 9.6e-34 116.8 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pkinase PF00069.25 EKX37725.1 - 1.1e-52 179.0 0.0 1.3e-52 178.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX37725.1 - 1.6e-30 106.3 0.0 1.8e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX37725.1 - 0.00023 20.6 0.0 0.0003 20.2 0.0 1.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EKX37725.1 - 0.0044 17.0 0.0 0.0064 16.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EKX37725.1 - 0.0045 16.0 0.0 0.0081 15.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EKX37725.1 - 0.02 14.3 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_7 PF13499.6 EKX37726.1 - 3.5e-39 133.1 1.9 1.1e-10 41.7 0.0 4.9 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 EKX37726.1 - 2.1e-37 123.9 2.4 2.8e-05 23.4 0.6 7.8 7 0 0 7 7 7 7 EF hand EF-hand_6 PF13405.6 EKX37726.1 - 2.1e-31 105.1 0.9 9.9e-06 25.1 0.2 7.7 7 0 0 7 7 7 5 EF-hand domain EF-hand_5 PF13202.6 EKX37726.1 - 2.2e-28 96.5 11.0 8.8e-05 21.8 0.1 7.6 7 0 0 7 7 7 5 EF hand AOX PF01786.17 EKX37726.1 - 1.7e-22 80.1 0.4 4e-22 78.9 0.1 1.7 2 0 0 2 2 2 1 Alternative oxidase EF-hand_8 PF13833.6 EKX37726.1 - 5.6e-20 70.9 7.3 0.00058 19.6 0.0 6.7 3 3 4 7 7 7 7 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX37726.1 - 0.00038 20.7 2.5 9.4 6.6 0.0 4.5 3 1 1 5 5 5 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EKX37726.1 - 0.00043 20.6 0.0 0.041 14.2 0.0 3.5 3 1 0 3 3 3 1 EF-hand domain cNMP_binding PF00027.29 EKX37726.1 - 0.0099 15.9 0.1 0.03 14.4 0.1 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF2624 PF11116.8 EKX37726.1 - 0.027 15.4 2.1 1.5 9.8 0.1 3.4 4 0 0 4 4 2 0 Protein of unknown function (DUF2624) Toprim_2 PF13155.6 EKX37726.1 - 0.031 14.7 3.0 3.8 8.0 0.8 4.4 3 1 2 5 5 4 0 Toprim-like OST-HTH PF12872.7 EKX37726.1 - 0.042 13.7 0.1 0.62 9.9 0.0 3.0 3 0 0 3 3 3 0 OST-HTH/LOTUS domain DUF2201 PF09967.9 EKX37726.1 - 0.17 12.0 1.7 0.35 11.0 0.1 2.4 3 0 0 3 3 2 0 VWA-like domain (DUF2201) DUF2666 PF10869.8 EKX37726.1 - 0.64 10.2 5.0 4.7 7.4 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) DUF1002 PF06207.11 EKX37726.1 - 1.4 8.4 7.9 9.4 5.7 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1002) DUF3349 PF11829.8 EKX37726.1 - 9.3 7.1 8.2 1.5 9.6 0.1 3.6 4 0 0 4 4 3 0 Protein of unknown function (DUF3349) Nsp1_C PF05064.13 EKX37727.1 - 7.7e-08 32.1 0.7 1.2e-07 31.5 0.7 1.3 1 0 0 1 1 1 1 Nsp1-like C-terminal region DUF262 PF03235.14 EKX37729.1 - 0.0025 18.0 0.3 0.019 15.2 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function DUF262 ADIP PF11559.8 EKX37729.1 - 0.011 15.8 1.7 0.021 14.9 1.7 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 EKX37729.1 - 0.023 14.2 3.2 0.04 13.4 3.2 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 BBP1_C PF15272.6 EKX37729.1 - 0.027 14.3 2.7 0.073 12.9 1.0 2.1 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Mu-like_Pro PF10123.9 EKX37729.1 - 0.052 13.1 1.9 0.11 12.0 1.9 1.5 1 0 0 1 1 1 0 Mu-like prophage I protein BRE1 PF08647.11 EKX37729.1 - 0.079 13.0 5.7 0.41 10.7 2.5 2.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase BLOC1_2 PF10046.9 EKX37729.1 - 0.14 12.4 5.4 0.32 11.3 5.4 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 EKX37729.1 - 0.45 9.3 6.2 0.77 8.6 6.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Cofilin_ADF PF00241.20 EKX37730.1 - 7.9e-35 119.3 0.3 8.8e-35 119.1 0.3 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF1664 PF07889.12 EKX37731.1 - 0.41 10.7 6.5 1.5 8.9 2.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) HAD_SAK_2 PF18143.1 EKX37731.1 - 0.46 10.8 3.9 0.4 11.0 1.7 2.0 2 0 0 2 2 2 0 HAD domain in Swiss Army Knife RNA repair proteins Myb_DNA-binding PF00249.31 EKX37733.1 - 2.2e-06 27.7 0.0 6.1e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EKX37734.1 - 2.3e-06 27.7 0.0 6.1e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain Acyltransferase PF01553.21 EKX37735.1 - 3.4e-27 94.7 0.0 4.7e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase SDA1 PF05285.12 EKX37739.1 - 0.23 10.9 72.3 0.28 10.6 72.3 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 EKX37739.1 - 1.4 8.2 62.7 1.6 8.0 62.7 1.1 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 EKX37739.1 - 4.7 5.9 27.8 5.6 5.6 27.8 1.0 1 0 0 1 1 1 0 Presenilin ubiquitin PF00240.23 EKX37742.1 - 6.5e-33 112.3 1.4 1e-32 111.7 0.5 1.9 2 0 0 2 2 2 1 Ubiquitin family Sod_Ni PF09055.11 EKX37742.1 - 7.5e-32 110.6 0.5 1.2e-31 109.9 0.5 1.3 1 0 0 1 1 1 1 Nickel-containing superoxide dismutase Rad60-SLD PF11976.8 EKX37742.1 - 5.2e-16 58.2 0.7 1.1e-15 57.1 0.7 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EKX37742.1 - 0.00038 20.9 0.1 0.0013 19.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EKX37742.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EKX37742.1 - 0.019 15.3 0.1 0.044 14.1 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EKX37742.1 - 0.028 14.5 0.0 0.082 13.0 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EKX37742.1 - 0.08 13.5 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EKX37742.1 - 0.29 11.2 1.0 23 5.1 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain DUF3638 PF12340.8 EKX37744.1 - 4.4e-26 91.6 0.0 8.8e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EKX37744.1 - 9.6e-15 53.7 0.4 2e-14 52.7 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) EF-hand_7 PF13499.6 EKX37744.1 - 1.2e-10 41.7 3.0 1.2e-05 25.6 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX37744.1 - 4e-08 32.6 8.5 0.0024 17.7 0.2 4.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 EKX37744.1 - 4.3e-08 32.9 3.7 0.011 15.5 0.0 3.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EKX37744.1 - 2e-07 30.1 7.7 0.0013 18.1 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 EKX37744.1 - 0.00016 21.0 6.6 0.028 13.9 0.2 4.1 4 0 0 4 4 4 2 EF hand Vps62 PF06101.11 EKX37744.1 - 0.0024 16.3 0.0 0.0043 15.4 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 ResIII PF04851.15 EKX37744.1 - 0.055 13.5 0.0 0.055 13.5 0.0 2.7 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit DUF2203 PF09969.9 EKX37744.1 - 3 8.6 8.4 7.1 7.4 0.0 3.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Rubredoxin PF00301.20 EKX37745.1 - 0.018 15.0 9.5 0.067 13.2 5.6 2.7 2 1 0 2 2 2 0 Rubredoxin VIT1 PF01988.19 EKX37745.1 - 0.031 14.1 1.0 6.5 6.6 0.1 2.3 2 0 0 2 2 2 0 VIT family DUF2654 PF10849.8 EKX37745.1 - 0.031 14.5 0.1 0.096 12.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2654) zf-Mss51 PF13824.6 EKX37745.1 - 0.095 12.8 0.7 7.4 6.7 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Zn_Tnp_IS1595 PF12760.7 EKX37745.1 - 0.23 11.5 0.9 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 EKX37745.1 - 0.39 10.9 3.5 1 9.5 3.5 1.7 1 1 0 1 1 1 0 Zinc ribbon domain DUF4366 PF14283.6 EKX37745.1 - 0.48 10.5 3.1 0.58 10.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) EF-hand_1 PF00036.32 EKX37746.1 - 7.3e-08 31.4 1.1 0.001 18.4 0.9 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX37746.1 - 3.4e-07 29.7 0.9 0.022 14.7 0.8 2.9 2 1 1 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EKX37746.1 - 6.2e-07 29.8 0.3 1.6e-06 28.4 0.3 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EKX37746.1 - 5.2e-05 23.0 1.5 0.0004 20.2 0.7 2.4 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX37746.1 - 0.0029 17.0 0.9 0.21 11.2 0.3 2.5 2 0 0 2 2 2 1 EF hand Uso1_p115_C PF04871.13 EKX37746.1 - 0.057 13.8 0.7 0.057 13.8 0.7 2.1 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region BK_channel_a PF03493.18 EKX37747.1 - 1.9e-32 111.3 0.1 4.8e-28 97.2 0.0 3.3 2 1 0 2 2 2 2 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 EKX37747.1 - 5.6e-12 45.4 5.3 1.5e-11 44.1 5.3 1.7 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EKX37747.1 - 0.00024 20.4 12.7 0.08 12.2 6.6 2.5 1 1 1 2 2 2 2 Ion transport protein TrkA_N PF02254.18 EKX37747.1 - 0.094 13.0 0.0 23 5.2 0.0 2.6 2 0 0 2 2 2 0 TrkA-N domain Vma12 PF11712.8 EKX37747.1 - 0.11 12.6 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Nfu_N PF08712.11 EKX37747.1 - 0.28 11.3 1.0 3.4 7.8 0.2 2.5 2 0 0 2 2 2 0 Scaffold protein Nfu/NifU N terminal Lig_chan PF00060.26 EKX37747.1 - 4.4 7.1 6.0 72 3.2 6.0 2.6 1 1 0 1 1 1 0 Ligand-gated ion channel WD40 PF00400.32 EKX37748.1 - 2.2e-17 63.1 19.4 0.00044 21.0 0.1 6.5 6 1 0 6 6 6 4 WD domain, G-beta repeat VID27 PF08553.10 EKX37748.1 - 0.0059 15.7 0.0 0.13 11.3 0.0 2.1 1 1 1 2 2 2 2 VID27 C-terminal WD40-like domain LRR_4 PF12799.7 EKX37749.1 - 2.1e-09 37.5 9.3 3.6e-06 27.2 1.0 2.1 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX37749.1 - 6.8e-09 35.4 9.2 2.2e-05 24.1 0.9 2.0 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 EKX37749.1 - 0.0022 18.3 9.3 2.2 9.2 0.2 3.2 3 0 0 3 3 3 3 Leucine Rich Repeat LRR_9 PF14580.6 EKX37749.1 - 0.048 13.2 0.3 0.057 12.9 0.3 1.2 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 EKX37749.1 - 4.7 7.5 6.3 15 6.0 0.1 3.0 3 0 0 3 3 3 0 Leucine Rich repeat PfkB PF00294.24 EKX37750.1 - 8e-21 74.6 0.1 7.6e-11 41.9 0.2 2.2 1 1 1 2 2 2 2 pfkB family carbohydrate kinase PRK PF00485.18 EKX37750.1 - 0.016 14.9 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Cation_efflux PF01545.21 EKX37751.1 - 4.3e-15 56.0 3.3 5.9e-15 55.5 3.3 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EKX37751.1 - 1.7e-12 47.2 2.6 3e-12 46.5 2.6 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Protoglobin PF11563.8 EKX37751.1 - 0.056 13.3 0.6 0.12 12.3 0.1 1.8 2 0 0 2 2 2 0 Protoglobin PDZ_6 PF17820.1 EKX37752.1 - 1.6e-08 34.3 0.0 4.6e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX37752.1 - 1.3e-06 28.6 0.0 3.6e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX37752.1 - 0.00012 22.3 0.1 0.00038 20.7 0.0 1.8 2 0 0 2 2 2 1 PDZ domain GRASP55_65 PF04495.14 EKX37752.1 - 0.09 13.1 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Peptidase_M54 PF07998.11 EKX37752.1 - 0.18 11.8 0.5 0.4 10.6 0.1 1.7 2 0 0 2 2 2 0 Peptidase family M54 GAS PF13851.6 EKX37752.1 - 0.68 9.2 41.5 1.6 8.1 6.3 3.5 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding EPOP PF15223.6 EKX37752.1 - 1.5 8.1 11.5 0.5 9.7 6.6 2.3 1 1 1 2 2 2 0 Elongin BC and Polycomb repressive complex 2-associated protein FliD_N PF02465.18 EKX37752.1 - 4.9 7.9 19.2 3 8.6 0.6 4.2 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus CENP-F_leu_zip PF10473.9 EKX37752.1 - 7.9 6.5 49.2 1.6 8.8 10.9 3.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Amino_oxidase PF01593.24 EKX37753.1 - 1.6e-22 80.4 0.0 3.5e-19 69.4 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EKX37753.1 - 1.5e-17 63.5 0.0 4.1e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EKX37753.1 - 1.1e-09 37.9 0.0 3.1e-08 33.1 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EKX37753.1 - 5.2e-09 36.2 0.0 1.3e-06 28.2 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 EKX37753.1 - 4.2e-06 26.1 0.3 0.00057 19.1 0.3 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EKX37753.1 - 8.4e-06 25.2 0.1 1.6e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EKX37753.1 - 1.2e-05 24.7 0.1 2.4e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 EKX37753.1 - 3.4e-05 23.2 0.1 8.1e-05 22.0 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EKX37753.1 - 9e-05 23.0 0.1 0.0002 21.9 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EKX37753.1 - 9.6e-05 21.8 0.1 0.0051 16.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EKX37753.1 - 0.00017 20.5 0.3 0.00033 19.5 0.2 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 EKX37753.1 - 0.00024 20.6 0.0 0.00086 18.8 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FMO-like PF00743.19 EKX37753.1 - 0.00037 19.1 0.5 0.00094 17.7 0.3 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Lycopene_cycl PF05834.12 EKX37753.1 - 0.0023 17.0 0.1 0.023 13.8 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EKX37753.1 - 0.0024 17.2 0.0 0.0045 16.3 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EKX37753.1 - 0.0034 17.0 0.1 0.0063 16.1 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 EKX37753.1 - 0.023 14.6 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MCRA PF06100.11 EKX37753.1 - 0.024 13.4 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 MCRA family ApbA PF02558.16 EKX37753.1 - 0.092 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 EKX37753.1 - 0.14 12.2 0.7 0.47 10.4 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Asp PF00026.23 EKX37754.1 - 4.3e-26 92.1 0.0 2.2e-16 60.2 0.0 2.8 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EKX37754.1 - 5.4e-09 36.5 0.0 0.00063 20.0 0.0 2.6 2 0 0 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EKX37754.1 - 0.035 14.7 0.0 22 5.8 0.0 3.5 3 0 0 3 3 3 0 Aspartyl protease PDZ PF00595.24 EKX37756.1 - 1.2e-13 51.2 1.6 1.2e-13 51.2 1.6 2.0 2 0 0 2 2 1 1 PDZ domain PDZ_6 PF17820.1 EKX37756.1 - 3.7e-12 45.9 0.2 7e-12 45.0 0.2 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX37756.1 - 7e-12 45.5 1.1 1.4e-11 44.5 1.1 1.5 1 0 0 1 1 1 1 PDZ domain APG6_N PF17675.1 EKX37756.1 - 0.0045 17.5 30.8 0.0072 16.9 6.2 2.2 1 1 1 2 2 2 2 Apg6 coiled-coil region CCDC85 PF10226.9 EKX37756.1 - 0.0057 16.4 1.2 0.0057 16.4 1.2 2.7 1 1 1 2 2 1 1 CCDC85 family DUF724 PF05266.14 EKX37756.1 - 0.008 16.0 6.8 0.008 16.0 6.8 2.3 1 1 0 2 2 2 1 Protein of unknown function (DUF724) Tricorn_PDZ PF14685.6 EKX37756.1 - 0.0084 16.1 0.2 0.063 13.3 0.3 2.5 2 0 0 2 2 2 1 Tricorn protease PDZ domain IFP_35_N PF07334.13 EKX37756.1 - 0.066 13.3 0.3 0.066 13.3 0.3 2.8 2 1 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus YabA PF06156.13 EKX37756.1 - 0.087 13.5 19.0 0.47 11.1 0.5 3.3 2 1 1 3 3 3 0 Initiation control protein YabA Rootletin PF15035.6 EKX37756.1 - 0.11 12.6 31.7 0.073 13.1 21.1 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion BRE1 PF08647.11 EKX37756.1 - 0.16 12.1 28.5 0.21 11.7 13.4 3.4 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase zf-C4H2 PF10146.9 EKX37756.1 - 0.22 11.8 15.6 0.12 12.7 12.8 1.9 1 1 1 2 2 2 0 Zinc finger-containing protein Filament PF00038.21 EKX37756.1 - 0.63 9.6 24.5 1.6 8.2 24.5 1.5 1 1 0 1 1 1 0 Intermediate filament protein Fez1 PF06818.15 EKX37756.1 - 1 9.8 24.8 1.9 8.9 4.3 2.2 1 1 1 2 2 2 0 Fez1 CPSF100_C PF13299.6 EKX37756.1 - 1.4 9.1 6.0 2.6 8.2 6.0 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal GAS PF13851.6 EKX37756.1 - 1.6 8.1 29.4 29 3.9 19.7 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 EKX37756.1 - 3.1 7.8 27.5 7.5 6.6 17.2 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CALCOCO1 PF07888.11 EKX37756.1 - 3.3 6.5 26.5 0.4 9.5 18.0 2.1 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like bZIP_1 PF00170.21 EKX37756.1 - 4 7.6 13.3 13 6.0 2.5 3.4 2 1 1 3 3 3 0 bZIP transcription factor ZapB PF06005.12 EKX37756.1 - 8.3 6.9 27.3 31 5.1 2.8 3.6 2 1 0 2 2 2 0 Cell division protein ZapB WDCP PF15390.6 EKX37756.1 - 9.1 4.5 12.8 13 4.1 12.8 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family NAD_binding_1 PF00175.21 EKX37757.1 - 1.4e-11 45.0 0.0 2.2e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EKX37757.1 - 0.046 13.9 0.2 5.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Ferric reductase NAD binding domain SAICAR_synt PF01259.18 EKX37759.1 - 4.8e-46 157.4 0.0 5.7e-45 153.9 0.0 2.0 1 1 0 1 1 1 1 SAICAR synthetase AIRC PF00731.20 EKX37760.1 - 3.3e-53 179.3 0.2 4e-53 179.0 0.2 1.1 1 0 0 1 1 1 1 AIR carboxylase Abhydrolase_6 PF12697.7 EKX37761.1 - 0.037 14.6 0.2 0.21 12.1 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Pro_isomerase PF00160.21 EKX37762.1 - 4.1e-28 98.7 0.0 5e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Fe-S_biosyn PF01521.20 EKX37763.1 - 2.3e-20 72.8 0.0 3.1e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis SCO1-SenC PF02630.14 EKX37764.1 - 5.8e-48 162.2 0.0 7.3e-48 161.9 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 EKX37764.1 - 0.0033 17.3 0.0 0.0061 16.5 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EKX37764.1 - 0.034 14.5 0.0 0.063 13.6 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like Peptidase_C23 PF05379.11 EKX37764.1 - 0.1 12.8 0.0 0.37 10.9 0.0 1.9 2 0 0 2 2 2 0 Carlavirus endopeptidase DcpS_C PF11969.8 EKX37765.1 - 1.4e-20 73.9 0.4 1.9e-20 73.4 0.4 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EKX37765.1 - 1e-08 35.8 0.3 1.9e-08 35.0 0.3 1.5 1 0 0 1 1 1 1 HIT domain DUF436 PF04260.12 EKX37765.1 - 0.03 13.9 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF436) COG7 PF10191.9 EKX37765.1 - 0.21 9.8 0.0 0.27 9.4 0.0 1.0 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) C2 PF00168.30 EKX37766.1 - 5.9e-15 55.4 0.1 6.5e-15 55.3 0.1 1.0 1 0 0 1 1 1 1 C2 domain ubiquitin PF00240.23 EKX37769.1 - 5e-33 112.7 0.5 8.1e-33 112.0 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin family HMG_box PF00505.19 EKX37769.1 - 5.7e-16 58.7 0.4 1.2e-15 57.6 0.4 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box Rad60-SLD PF11976.8 EKX37769.1 - 5.8e-16 58.1 0.7 9e-16 57.5 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like HMG_box_2 PF09011.10 EKX37769.1 - 1.8e-07 31.6 0.2 5.1e-07 30.2 0.2 1.7 1 0 0 1 1 1 1 HMG-box domain Ubiquitin_2 PF14560.6 EKX37769.1 - 0.00018 21.9 0.2 0.0011 19.4 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain CHDNT PF08073.12 EKX37769.1 - 0.0027 17.6 0.1 0.0027 17.6 0.1 1.7 2 0 0 2 2 2 1 CHDNT (NUC034) domain DUF4776 PF16003.5 EKX37769.1 - 0.003 16.6 7.6 0.0035 16.4 7.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4776) Rad60-SLD_2 PF13881.6 EKX37769.1 - 0.0073 16.4 0.1 0.0073 16.4 0.1 2.7 2 1 1 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EKX37769.1 - 0.0076 16.2 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 EKX37769.1 - 0.011 16.3 1.3 0.024 15.2 1.3 1.6 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 EKX37769.1 - 0.031 14.6 0.1 0.031 14.6 0.1 1.7 2 0 0 2 2 2 0 Ubiquitin-like domain Protamine_like PF06382.11 EKX37769.1 - 0.086 13.0 5.1 0.12 12.5 5.1 1.2 1 0 0 1 1 1 0 Protamine and protamine like Ubiquitin_4 PF18036.1 EKX37769.1 - 0.21 11.6 1.0 19 5.4 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain Plexin_cytopl PF08337.12 EKX37769.1 - 0.5 9.0 3.7 1.4 7.4 0.3 2.0 2 0 0 2 2 2 0 Plexin cytoplasmic RasGAP domain TIG PF01833.24 EKX37770.1 - 3.4e-51 171.2 159.6 2e-05 24.5 1.7 23.1 22 0 0 22 22 22 18 IPT/TIG domain 2OG-Fe_Oxy_2 PF10014.9 EKX37770.1 - 6e-06 26.2 0.0 19 5.0 0.0 4.3 4 0 0 4 4 4 4 2OG-Fe dioxygenase EGF_CA PF07645.15 EKX37770.1 - 0.0048 17.1 2.6 0.03 14.5 2.6 2.4 1 0 0 1 1 1 1 Calcium-binding EGF domain GCD14 PF08704.10 EKX37770.1 - 0.026 14.2 22.2 24 4.5 0.2 6.4 6 0 0 6 6 6 0 tRNA methyltransferase complex GCD14 subunit PAP_central PF04928.17 EKX37771.1 - 6.7e-79 264.4 0.1 7.6e-79 264.2 0.1 1.0 1 0 0 1 1 1 1 Poly(A) polymerase central domain NTP_transf_2 PF01909.23 EKX37771.1 - 1.1e-06 28.9 0.0 2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF4269 PF14091.6 EKX37771.1 - 0.022 15.0 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) CLP1_P PF16575.5 EKX37772.1 - 1.4e-37 129.3 0.0 9.3e-37 126.7 0.0 2.3 4 0 0 4 4 4 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 EKX37772.1 - 1.9e-24 85.7 0.0 3.2e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 EKX37772.1 - 2.1e-21 76.5 0.0 3.4e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MMR_HSR1 PF01926.23 EKX37772.1 - 0.00031 20.8 0.0 0.001 19.1 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EKX37772.1 - 0.00041 20.8 0.0 0.0009 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 EKX37772.1 - 0.0017 18.1 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_35 PF14516.6 EKX37772.1 - 0.0097 14.8 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain AAA_10 PF12846.7 EKX37772.1 - 0.018 14.0 0.0 0.11 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain AAA PF00004.29 EKX37772.1 - 0.019 15.4 0.0 0.067 13.6 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 EKX37772.1 - 0.055 12.9 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EKX37772.1 - 0.09 13.0 0.0 0.19 12.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 EKX37772.1 - 0.096 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EKX37772.1 - 0.11 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 EKX37772.1 - 0.15 12.6 0.0 0.34 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 EKX37772.1 - 0.18 11.9 0.0 0.26 11.4 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_19 PF13245.6 EKX37772.1 - 0.18 12.1 0.0 0.94 9.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain Peptidase_S41 PF03572.18 EKX37772.1 - 0.19 11.3 0.0 0.38 10.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase family S41 DUF815 PF05673.13 EKX37772.1 - 0.22 10.6 0.0 0.37 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PKD_channel PF08016.12 EKX37773.1 - 1.4e-12 47.1 6.9 1.8e-12 46.7 6.9 1.1 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 EKX37773.1 - 1.6e-12 47.2 4.4 1.8e-12 47.0 4.4 1.1 1 0 0 1 1 1 1 Ion transport protein FA_desaturase PF00487.24 EKX37773.1 - 0.036 13.9 2.9 0.044 13.6 2.9 1.1 1 0 0 1 1 1 0 Fatty acid desaturase C2 PF00168.30 EKX37774.1 - 5.9e-15 55.4 0.1 6.5e-15 55.3 0.1 1.0 1 0 0 1 1 1 1 C2 domain CHB_HEX_C_1 PF13290.6 EKX37775.1 - 6.7e-11 42.0 0.1 1.3e-10 41.1 0.1 1.5 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 EKX37775.1 - 6.4e-09 35.8 0.1 1.7e-08 34.5 0.1 1.8 1 0 0 1 1 1 1 Fn3 associated WW PF00397.26 EKX37775.1 - 0.012 15.7 3.2 0.012 15.7 3.2 2.7 3 0 0 3 3 3 0 WW domain IQ PF00612.27 EKX37775.1 - 0.016 15.0 6.7 0.31 10.9 0.4 2.8 2 0 0 2 2 2 0 IQ calmodulin-binding motif Ank_5 PF13857.6 EKX37776.1 - 6.4e-13 48.7 0.2 2.1e-06 27.9 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX37776.1 - 1.1e-11 45.1 0.0 1.3e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX37776.1 - 3.2e-11 43.5 0.0 1.5e-10 41.4 0.1 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX37776.1 - 4e-11 42.8 0.0 1.1e-05 25.7 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EKX37776.1 - 8.3e-08 31.9 0.0 0.013 15.9 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Collagen PF01391.18 EKX37777.1 - 2.7e-31 107.1 103.2 2.3e-06 27.2 35.5 4.3 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Syntaxin PF00804.25 EKX37777.1 - 0.026 14.2 0.3 0.037 13.7 0.3 1.1 1 0 0 1 1 1 0 Syntaxin DHC_N1 PF08385.12 EKX37777.1 - 0.12 11.0 0.1 0.15 10.7 0.1 1.0 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 KELK PF15796.5 EKX37777.1 - 0.22 12.0 2.6 0.31 11.5 2.6 1.2 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase RAWUL PF16207.5 EKX37778.1 - 1.7e-09 38.2 0.1 4.1e-09 37.0 0.1 1.7 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-C3HC4_2 PF13923.6 EKX37778.1 - 9.9e-09 34.9 4.9 2.2e-08 33.8 4.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX37778.1 - 2.1e-07 30.7 5.0 5.4e-07 29.4 5.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX37778.1 - 5e-07 29.6 5.2 1.1e-06 28.5 5.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EKX37778.1 - 1.4e-05 25.0 1.3 1.4e-05 25.0 1.3 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 EKX37778.1 - 4.4e-05 23.7 3.7 0.0001 22.6 3.7 1.6 1 0 0 1 1 1 1 Ring finger domain DUF3337 PF11816.8 EKX37778.1 - 0.00013 21.9 4.0 0.00038 20.4 4.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3337) zf-C3HC4_3 PF13920.6 EKX37778.1 - 0.001 18.9 2.8 0.0021 17.9 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EKX37778.1 - 0.003 17.7 3.9 0.0081 16.3 3.9 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EKX37778.1 - 0.0035 17.6 3.3 0.011 16.0 3.3 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EKX37778.1 - 0.0078 16.1 3.3 0.0078 16.1 3.3 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 EKX37778.1 - 0.0083 16.0 0.5 0.014 15.2 0.1 1.6 2 0 0 2 2 2 1 zf-RING of BARD1-type protein DUF1272 PF06906.11 EKX37778.1 - 0.035 14.2 2.3 0.075 13.1 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) CBM26 PF16738.5 EKX37779.1 - 0.00065 19.9 0.0 0.0025 18.0 0.0 1.9 2 0 0 2 2 2 1 Starch-binding module 26 PH PF00169.29 EKX37780.1 - 0.003 18.0 0.9 0.081 13.4 0.3 3.1 2 1 0 2 2 2 1 PH domain IQ PF00612.27 EKX37781.1 - 3.2e-05 23.3 37.1 0.56 10.2 0.0 9.7 9 0 0 9 9 9 8 IQ calmodulin-binding motif WW PF00397.26 EKX37781.1 - 5.1e-05 23.3 3.4 9.8e-05 22.4 3.4 1.5 1 0 0 1 1 1 1 WW domain TCR PF03638.15 EKX37782.1 - 7.8e-26 90.1 58.5 1.7e-13 50.6 23.7 2.1 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain EF-hand_1 PF00036.32 EKX37783.1 - 2.8e-14 51.5 1.1 0.00087 18.7 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 EKX37783.1 - 6.4e-14 52.2 3.9 1.7e-07 31.6 0.2 3.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX37783.1 - 2.9e-13 48.6 2.7 0.0001 21.9 0.1 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 EKX37783.1 - 1.5e-06 27.9 2.6 0.014 15.2 0.0 3.6 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX37783.1 - 2.1e-05 23.8 0.4 0.052 13.1 0.0 3.3 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 EKX37783.1 - 0.11 12.8 0.0 12 6.3 0.0 2.5 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region HA1 PF18239.1 EKX37783.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Hemagglutinin I DUF1771 PF08590.10 EKX37784.1 - 0.016 15.6 1.7 0.033 14.6 1.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) DNA_pol_A PF00476.20 EKX37785.1 - 7.7e-135 449.8 0.0 1.3e-134 449.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family A 5_3_exonuc_N PF02739.16 EKX37785.1 - 1.5e-49 168.0 0.0 3e-49 167.0 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 EKX37785.1 - 2.4e-24 85.7 0.1 1.1e-23 83.7 0.1 2.2 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold TPR_1 PF00515.28 EKX37785.1 - 2.8e-05 23.7 0.0 0.039 13.8 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX37785.1 - 4.7e-05 23.5 0.0 0.14 12.6 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX37785.1 - 0.00015 21.4 0.0 0.0047 16.6 0.0 2.4 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 EKX37785.1 - 0.00019 21.3 0.0 0.91 9.8 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat DNA_pol_A_exo1 PF01612.20 EKX37785.1 - 0.00057 19.6 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease HHH_2 PF12826.7 EKX37785.1 - 0.0016 18.5 0.0 0.0072 16.4 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif TPR_14 PF13428.6 EKX37785.1 - 0.0058 17.4 0.1 2.6 9.1 0.0 3.3 1 1 1 2 2 2 1 Tetratricopeptide repeat HHH_5 PF14520.6 EKX37785.1 - 0.0097 16.5 0.1 0.045 14.4 0.1 2.2 1 0 0 1 1 1 1 Helix-hairpin-helix domain NYN_YacP PF05991.11 EKX37785.1 - 0.024 14.6 0.1 0.073 13.0 0.1 1.8 1 0 0 1 1 1 0 YacP-like NYN domain TPR_16 PF13432.6 EKX37785.1 - 0.043 14.5 0.0 0.1 13.2 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Complex1_LYR_2 PF13233.6 EKX37785.1 - 0.17 12.7 1.0 0.78 10.5 0.0 2.6 2 1 0 2 2 2 0 Complex1_LYR-like C2 PF00168.30 EKX37786.1 - 5.9e-15 55.4 0.1 6.5e-15 55.3 0.1 1.0 1 0 0 1 1 1 1 C2 domain HSBP1 PF06825.12 EKX37788.1 - 0.00034 20.4 0.4 0.00089 19.1 0.4 1.7 1 0 0 1 1 1 1 Heat shock factor binding protein 1 EF-hand_7 PF13499.6 EKX37789.1 - 1.6e-19 70.1 9.5 2.6e-14 53.4 2.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX37789.1 - 1.8e-14 52.1 11.4 0.00035 19.9 0.2 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EKX37789.1 - 1.2e-13 49.8 7.0 0.00041 20.0 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EKX37789.1 - 1.6e-10 40.0 7.4 0.0018 17.7 0.2 3.8 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EKX37789.1 - 4e-10 39.4 6.5 9.5e-07 28.6 0.6 4.0 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 EKX37789.1 - 7.9e-05 22.9 2.7 0.00077 19.7 0.1 2.6 3 0 0 3 3 3 1 EF-hand domain DUF2666 PF10869.8 EKX37789.1 - 0.015 15.6 1.8 0.45 10.7 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2666) EF-hand_11 PF08976.11 EKX37789.1 - 0.17 12.8 0.1 3.5 8.6 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain LRR_6 PF13516.6 EKX37790.1 - 8.6e-13 47.2 40.1 0.014 15.4 0.0 11.3 12 0 0 12 12 12 6 Leucine Rich repeat LRR_4 PF12799.7 EKX37790.1 - 2.5e-09 37.3 35.8 0.024 15.0 1.7 9.9 10 2 3 13 13 13 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX37790.1 - 0.028 14.9 34.5 13 6.8 0.3 10.7 12 1 0 12 12 12 0 Leucine Rich Repeat LRR_8 PF13855.6 EKX37790.1 - 0.78 9.6 43.3 3.9 7.3 0.0 10.2 10 3 2 12 12 12 0 Leucine rich repeat Beta_helix PF13229.6 EKX37791.1 - 0.007 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Right handed beta helix region WW PF00397.26 EKX37791.1 - 0.01 15.9 1.4 0.01 15.9 1.4 2.7 2 0 0 2 2 2 0 WW domain RNA_pol_Rpc4 PF05132.14 EKX37791.1 - 9.8 6.6 18.2 0.93 9.9 9.8 2.8 2 0 0 2 2 2 0 RNA polymerase III RPC4 JmjN PF02375.17 EKX37792.1 - 9.5e-06 25.5 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 jmjN domain DUF1799 PF08809.11 EKX37792.1 - 0.13 12.5 0.0 2.2 8.5 0.0 2.6 2 1 1 3 3 3 0 Phage related hypothetical protein (DUF1799) Proteasom_Rpn13 PF04683.13 EKX37793.1 - 2.6e-26 92.0 0.1 3.5e-26 91.6 0.1 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Glyco_transf_22 PF03901.17 EKX37794.1 - 0.079 12.2 0.0 0.099 11.8 0.0 1.1 1 0 0 1 1 1 0 Alg9-like mannosyltransferase family Hydrolase_4 PF12146.8 EKX37795.1 - 2.2e-49 167.9 0.0 2.5e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EKX37795.1 - 2.4e-08 34.0 0.0 3.9e-07 30.0 0.1 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EKX37795.1 - 1.1e-06 29.5 0.0 1.4e-06 29.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EKX37795.1 - 7.9e-06 25.8 0.0 0.81 9.5 0.0 3.1 3 0 0 3 3 3 3 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EKX37795.1 - 0.00056 19.4 0.0 0.25 10.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EKX37795.1 - 0.00067 19.6 0.0 0.0031 17.4 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 EKX37795.1 - 0.0015 18.1 0.0 0.013 15.1 0.0 2.2 3 0 0 3 3 3 1 Dienelactone hydrolase family AXE1 PF05448.12 EKX37795.1 - 0.01 14.5 0.0 0.056 12.1 0.0 2.0 1 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) Peptidase_S28 PF05577.12 EKX37795.1 - 0.039 12.7 0.0 0.058 12.2 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Peptidase_S15 PF02129.18 EKX37795.1 - 0.052 13.1 0.0 0.61 9.6 0.0 2.0 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Lipase_3 PF01764.25 EKX37795.1 - 0.099 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF1749 PF08538.10 EKX37795.1 - 0.13 11.3 0.0 0.28 10.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) PDZ_2 PF13180.6 EKX37797.1 - 1.4e-10 41.3 0.1 1.9e-10 40.9 0.1 1.1 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX37797.1 - 3.8e-09 36.3 0.2 7e-09 35.4 0.1 1.5 1 1 1 2 2 2 1 PDZ domain PDZ PF00595.24 EKX37797.1 - 3.4e-06 27.3 0.0 5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX37797.1 - 0.0048 16.8 0.1 0.0083 16.1 0.1 1.5 1 1 0 1 1 1 1 Tricorn protease PDZ domain Ank PF00023.30 EKX37798.1 - 2.6e-26 90.8 4.0 3.4e-08 33.6 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 EKX37798.1 - 7.2e-24 84.2 1.0 9.1e-13 48.6 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX37798.1 - 8.9e-24 83.3 3.1 5.1e-09 36.2 0.2 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX37798.1 - 6.7e-22 77.6 3.3 7.2e-09 36.0 0.1 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX37798.1 - 1.6e-19 67.9 1.5 1.8e-06 27.9 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Methyltransf_11 PF08241.12 EKX37799.1 - 8.4e-20 71.2 0.0 1.6e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX37799.1 - 1.5e-18 67.3 0.0 3.1e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX37799.1 - 1.5e-17 63.7 0.0 3.2e-16 59.4 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EKX37799.1 - 4.8e-15 55.7 0.0 7.7e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX37799.1 - 6.4e-14 52.1 0.0 9.9e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX37799.1 - 3e-13 50.4 0.0 1.7e-12 47.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 EKX37799.1 - 0.0021 18.1 0.0 0.0042 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EKX37799.1 - 0.0024 17.8 0.0 0.027 14.3 0.0 2.2 1 1 0 1 1 1 1 Hypothetical methyltransferase DZR PF12773.7 EKX37799.1 - 0.0037 17.2 0.4 0.0085 16.1 0.4 1.5 1 0 0 1 1 1 1 Double zinc ribbon Methyltransf_9 PF08003.11 EKX37799.1 - 0.0063 15.5 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 EKX37799.1 - 0.0069 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain zinc-ribbon_6 PF10005.9 EKX37799.1 - 0.013 16.1 0.1 0.024 15.3 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Methyltransf_4 PF02390.17 EKX37799.1 - 0.04 13.4 0.0 0.33 10.4 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase zinc_ribbon_2 PF13240.6 EKX37799.1 - 0.23 11.2 0.8 0.53 10.1 0.8 1.7 1 0 0 1 1 1 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.13 EKX37799.1 - 0.82 9.4 8.4 0.052 13.2 1.5 2.3 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Fer2 PF00111.27 EKX37800.1 - 0.00027 20.8 4.1 0.00061 19.7 4.0 1.7 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain MCR PF18509.1 EKX37800.1 - 0.023 14.3 0.4 0.042 13.4 0.4 1.4 1 0 0 1 1 1 0 Magnetochrome domain EMP70 PF02990.16 EKX37802.1 - 3.9e-139 464.7 18.4 4.8e-137 457.8 18.4 2.3 1 1 0 1 1 1 1 Endomembrane protein 70 PKD_channel PF08016.12 EKX37803.1 - 1.9e-33 115.8 25.0 6.1e-32 110.8 25.0 2.6 1 1 0 1 1 1 1 Polycystin cation channel RCC1_2 PF13540.6 EKX37803.1 - 3.9e-28 96.6 30.0 6.9e-07 28.9 0.1 8.2 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Ion_trans PF00520.31 EKX37803.1 - 2.5e-09 36.7 23.9 2.5e-09 36.7 23.9 2.1 2 0 0 2 2 2 1 Ion transport protein FOLN PF09289.10 EKX37803.1 - 0.00011 22.4 0.9 0.1 12.8 0.1 2.8 3 0 0 3 3 3 2 Follistatin/Osteonectin-like EGF domain DX PF01666.17 EKX37803.1 - 0.61 10.6 2.4 4 8.0 0.7 2.9 2 0 0 2 2 2 0 DX module DUF4709 PF15821.5 EKX37803.1 - 6.4 7.1 7.6 3 8.2 1.1 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4709) Thioredoxin_8 PF13905.6 EKX37805.1 - 3.7e-29 100.9 0.0 5.1e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 EKX37805.1 - 3.7e-09 36.5 0.0 1.6e-06 28.0 0.1 2.1 1 1 1 2 2 2 2 Thioredoxin Redoxin PF08534.10 EKX37805.1 - 1e-05 25.3 0.0 1.4e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EKX37805.1 - 1.7e-05 24.7 0.0 1.9e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 EKX37805.1 - 8.7e-05 22.9 0.0 0.00012 22.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EKX37805.1 - 0.0015 18.7 0.0 0.0045 17.1 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like SCO1-SenC PF02630.14 EKX37805.1 - 0.061 13.2 0.0 0.083 12.8 0.0 1.2 1 0 0 1 1 1 0 SCO1/SenC DUF179 PF02622.15 EKX37806.1 - 5.1e-27 94.8 0.0 6.3e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 DUF4982 PF16355.5 EKX37806.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4982) T4_baseplate PF12322.8 EKX37807.1 - 0.12 11.8 8.2 0.14 11.6 8.2 1.1 1 0 0 1 1 1 0 T4 bacteriophage base plate protein RNase_J_C PF17770.1 EKX37807.1 - 0.44 11.6 6.2 1.4 10.1 6.2 1.7 1 1 0 1 1 1 0 Ribonuclease J C-terminal domain COMP PF11598.8 EKX37807.1 - 0.51 10.9 12.1 0.69 10.4 2.9 3.0 1 1 1 2 2 2 0 Cartilage oligomeric matrix protein DUF1059 PF06348.11 EKX37807.1 - 4.5 7.6 9.6 98 3.3 9.6 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1059) YtxH PF12732.7 EKX37807.1 - 8.1 7.1 11.4 23 5.6 11.4 1.8 1 1 0 1 1 1 0 YtxH-like protein FHA PF00498.26 EKX37808.1 - 2.5e-14 53.3 0.0 3.9e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 FHA domain MORN PF02493.20 EKX37809.1 - 3.6e-25 86.3 29.8 1.3e-09 37.4 4.5 4.0 4 0 0 4 4 4 4 MORN repeat zf-CCCH PF00642.24 EKX37810.1 - 0.00042 20.2 4.0 0.00069 19.5 4.0 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EKX37810.1 - 0.0013 19.4 0.3 0.0013 19.4 0.3 2.5 2 0 0 2 2 2 1 Torus domain TSSC4 PF15264.6 EKX37810.1 - 0.0056 16.9 3.3 0.015 15.6 0.8 2.5 1 1 1 2 2 2 1 Tumour suppressing sub-chromosomal transferable candidate 4 ProSAAS PF07259.12 EKX37810.1 - 0.019 14.9 1.8 0.032 14.2 1.8 1.2 1 0 0 1 1 1 0 ProSAAS precursor zf-CCCH_4 PF18044.1 EKX37810.1 - 0.025 14.4 3.3 0.043 13.6 3.3 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EKX37810.1 - 0.71 10.0 6.6 1.2 9.3 6.6 1.4 1 0 0 1 1 1 0 Zinc finger domain DivIC PF04977.15 EKX37810.1 - 3.7 7.4 7.0 9.4 6.1 7.0 1.6 1 0 0 1 1 1 0 Septum formation initiator Pro_isomerase PF00160.21 EKX37811.1 - 6.9e-32 110.9 0.1 7.7e-32 110.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GCP_C_terminal PF04130.13 EKX37814.1 - 6.7e-47 160.4 7.4 1.3e-46 159.5 7.4 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EKX37814.1 - 1.8e-39 136.2 2.0 3.6e-39 135.2 2.0 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal MFS_1 PF07690.16 EKX37815.1 - 2e-25 89.4 27.0 2e-25 89.4 27.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Complex1_51K PF01512.17 EKX37816.1 - 8.6e-49 165.3 0.0 1.4e-48 164.7 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 EKX37816.1 - 2.9e-27 94.6 0.1 6.1e-27 93.5 0.1 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 EKX37816.1 - 3.6e-06 26.7 0.4 9e-06 25.5 0.4 1.7 1 0 0 1 1 1 1 SLBB domain DUF3568 PF12092.8 EKX37816.1 - 0.011 15.8 0.5 0.025 14.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) Chloroa_b-bind PF00504.21 EKX37817.1 - 4.7e-42 144.2 0.0 6.1e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein CK_II_beta PF01214.18 EKX37818.1 - 0.051 13.4 0.7 0.093 12.5 0.7 1.3 1 0 0 1 1 1 0 Casein kinase II regulatory subunit Glycos_transf_2 PF00535.26 EKX37824.1 - 2.1e-05 24.4 0.5 4.6e-05 23.3 0.3 1.7 1 1 1 2 2 2 1 Glycosyl transferase family 2 A_amylase_inhib PF01356.19 EKX37824.1 - 0.038 14.0 0.2 0.11 12.5 0.1 1.7 2 0 0 2 2 2 0 Alpha amylase inhibitor Glyco_hydro_127 PF07944.12 EKX37824.1 - 0.089 11.3 0.1 0.13 10.7 0.1 1.2 1 0 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 Glyco_tranf_2_4 PF13704.6 EKX37824.1 - 0.089 13.3 0.2 0.3 11.7 0.2 2.0 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_transf_90 PF05686.12 EKX37825.1 - 5.9e-11 41.9 0.0 6.5e-11 41.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 EKX37825.1 - 0.0077 16.6 0.1 0.01 16.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 PL48 PF15903.5 EKX37825.1 - 0.06 12.3 0.0 0.062 12.3 0.0 1.0 1 0 0 1 1 1 0 Filopodia upregulated, FAM65 Peptidase_C32 PF05411.12 EKX37825.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.4 1 1 0 1 1 1 0 Equine arteritis virus putative proteinase DUF563 PF04577.14 EKX37826.1 - 5.2e-19 69.2 0.0 8.5e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Toxin_3 PF00537.18 EKX37826.1 - 0.025 14.8 1.2 0.064 13.5 1.2 1.6 1 0 0 1 1 1 0 Scorpion toxin-like domain DUF327 PF03885.13 EKX37831.1 - 0.00066 19.7 0.1 0.00078 19.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF327) APG5 PF04106.12 EKX37831.1 - 0.083 12.5 0.0 0.09 12.3 0.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg5 Thioredoxin PF00085.20 EKX37832.1 - 2e-11 43.8 0.0 2.2e-11 43.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EKX37832.1 - 0.0038 16.6 0.0 0.0038 16.6 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family SRCR PF00530.18 EKX37833.1 - 3e-19 69.4 1.1 3.3e-19 69.2 1.1 1.0 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 EKX37833.1 - 0.021 15.3 0.5 0.027 15.0 0.5 1.2 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain DUF327 PF03885.13 EKX37834.1 - 0.039 13.9 0.2 0.09 12.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF327) DUF5082 PF16888.5 EKX37835.1 - 0.016 15.5 0.7 0.017 15.4 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) SRCR PF00530.18 EKX37836.1 - 3.1e-26 91.8 9.7 3.9e-26 91.5 9.7 1.2 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 EKX37836.1 - 1.3e-05 25.6 0.7 2e-05 25.0 0.7 1.3 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain DUF3431 PF11913.8 EKX37837.1 - 2.2e-08 34.1 0.3 2.6e-08 33.9 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF3431 PF11913.8 EKX37838.1 - 2.2e-10 40.7 0.0 2.7e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) FlaC_arch PF05377.11 EKX37842.1 - 5 7.6 8.9 33 5.0 2.0 3.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) UQ_con PF00179.26 EKX37843.1 - 6.4e-46 155.5 0.0 7.3e-46 155.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PDH PF02153.17 EKX37845.1 - 1e-19 70.6 0.0 3.5e-19 68.8 0.0 1.7 1 1 0 1 1 1 1 Prephenate dehydrogenase DUF3431 PF11913.8 EKX37846.1 - 3.5e-14 53.1 2.5 9.5e-07 28.8 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3431) DUF3587 PF12132.8 EKX37846.1 - 0.047 13.1 0.0 0.089 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3587) Glyco_transf_90 PF05686.12 EKX37847.1 - 5.9e-13 48.5 0.0 6.4e-13 48.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 EKX37847.1 - 0.012 16.0 0.1 0.019 15.3 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 DUF563 PF04577.14 EKX37848.1 - 5.3e-19 69.2 0.0 8.9e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Toxin_3 PF00537.18 EKX37848.1 - 0.024 14.9 1.2 0.062 13.5 1.2 1.7 1 0 0 1 1 1 0 Scorpion toxin-like domain DAP10 PF07213.11 EKX37849.1 - 0.0046 16.9 1.3 0.17 11.8 0.1 2.5 2 0 0 2 2 2 2 DAP10 membrane protein ZU5 PF00791.20 EKX37849.1 - 0.01 16.2 0.0 0.028 14.7 0.0 1.7 1 0 0 1 1 1 0 ZU5 domain Glyco_transf_90 PF05686.12 EKX37850.1 - 4.1e-22 78.6 0.0 5.8e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 90 Izumo-Ig PF16706.5 EKX37850.1 - 0.017 15.2 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain Glyco_trans_1_2 PF13524.6 EKX37850.1 - 0.1 13.0 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 UCH PF00443.29 EKX37851.1 - 1.8e-48 165.3 0.0 2.2e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EKX37851.1 - 2.2e-17 63.7 0.5 5.7e-17 62.3 0.5 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EKX37851.1 - 1.2e-07 31.3 1.1 1.8e-07 30.8 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin family Peptidase_C98 PF15499.6 EKX37851.1 - 0.011 15.2 3.1 0.019 14.4 0.1 2.7 3 1 0 4 4 4 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Ubiquitin_2 PF14560.6 EKX37851.1 - 0.086 13.3 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain IBN_N PF03810.19 EKX37852.1 - 2.4e-08 33.8 1.8 2.5e-06 27.3 0.1 2.8 2 0 0 2 2 2 2 Importin-beta N-terminal domain CAP_GLY PF01302.25 EKX37853.1 - 1e-21 76.7 1.4 1.6e-21 76.1 1.4 1.3 1 0 0 1 1 1 1 CAP-Gly domain PPP5 PF08321.12 EKX37853.1 - 0.00085 19.6 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 PPP5 TPR repeat region WGR PF05406.15 EKX37854.1 - 0.083 13.0 0.6 35 4.5 0.0 3.2 3 0 0 3 3 3 0 WGR domain HD_assoc PF13286.6 EKX37854.1 - 0.099 13.2 0.9 0.9 10.1 0.0 2.8 2 0 0 2 2 2 0 Phosphohydrolase-associated domain Thioredoxin PF00085.20 EKX37856.1 - 3.2e-44 149.1 0.0 8.1e-22 77.2 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EKX37856.1 - 1.4e-12 47.9 0.0 1.2e-11 44.8 0.0 2.5 4 0 0 4 4 4 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EKX37856.1 - 2.2e-08 34.2 0.0 0.0072 16.5 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 EKX37856.1 - 4e-06 27.1 0.2 0.11 12.9 0.0 3.3 2 1 0 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 EKX37856.1 - 5.5e-06 25.9 0.0 0.0072 15.7 0.0 2.3 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EKX37856.1 - 1.7e-05 25.2 0.2 0.075 13.5 0.0 2.8 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_4 PF13462.6 EKX37856.1 - 0.0018 18.5 0.0 0.11 12.6 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin TraF PF13728.6 EKX37856.1 - 0.0085 15.9 0.0 0.054 13.3 0.0 2.0 2 0 0 2 2 2 1 F plasmid transfer operon protein Calsequestrin PF01216.17 EKX37856.1 - 0.011 14.9 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Calsequestrin AhpC-TSA PF00578.21 EKX37856.1 - 0.011 15.6 0.1 7.8 6.4 0.0 2.5 2 0 0 2 2 2 0 AhpC/TSA family Thioredoxin_3 PF13192.6 EKX37856.1 - 0.061 13.4 0.0 1.4 9.0 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_9 PF14595.6 EKX37856.1 - 0.14 11.9 0.2 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin Phage_H_T_join PF05521.11 EKX37857.1 - 0.19 12.3 0.2 1.2 9.7 0.0 2.4 2 0 0 2 2 2 0 Phage head-tail joining protein Rick_17kDa_Anti PF05433.15 EKX37857.1 - 1.6 8.6 10.6 6.9 6.6 10.6 2.0 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 EKX37857.1 - 1.7 8.7 11.2 2.3 8.3 9.6 2.1 2 0 0 2 2 2 0 Glycine zipper Pkinase PF00069.25 EKX37858.1 - 9e-37 126.9 0.0 1.2e-36 126.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX37858.1 - 8.7e-23 80.9 0.0 1.2e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase IFT57 PF10498.9 EKX37858.1 - 4.5e-12 45.6 0.0 5.5e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Kinase-like PF14531.6 EKX37858.1 - 0.0022 17.4 0.0 0.0038 16.6 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EKX37858.1 - 0.0055 15.5 0.0 0.0072 15.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Phage_H_T_join PF05521.11 EKX37859.1 - 0.074 13.6 0.0 0.28 11.7 0.0 2.0 1 0 0 1 1 1 0 Phage head-tail joining protein PTSIIA_gutA PF03829.13 EKX37859.1 - 0.28 11.1 1.8 1.8 8.5 0.2 2.6 3 0 0 3 3 3 0 PTS system glucitol/sorbitol-specific IIA component Pkinase PF00069.25 EKX37860.1 - 1.1e-60 205.2 0.0 1.3e-59 201.8 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX37860.1 - 7.3e-43 146.7 0.0 7.6e-42 143.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase IFT57 PF10498.9 EKX37860.1 - 1.9e-37 129.1 3.2 3.7e-37 128.2 3.2 1.4 1 1 0 1 1 1 1 Intra-flagellar transport protein 57 Kinase-like PF14531.6 EKX37860.1 - 2e-05 24.0 0.0 0.00013 21.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EKX37860.1 - 0.0012 18.2 0.0 0.0028 17.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EKX37860.1 - 0.004 16.0 0.1 0.0099 14.7 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Spc7 PF08317.11 EKX37860.1 - 0.089 11.7 9.3 0.2 10.5 9.3 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein KxDL PF10241.9 EKX37860.1 - 0.44 10.8 2.8 0.38 11.0 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein Atg14 PF10186.9 EKX37860.1 - 0.49 9.4 9.1 2 7.4 9.1 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 EKX37860.1 - 2.6 7.5 5.7 5.3 6.5 5.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Helicase_C PF00271.31 EKX37861.1 - 7.3e-23 81.0 0.0 1.8e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EKX37861.1 - 2.9e-18 66.2 0.0 7.1e-17 61.7 0.0 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EKX37861.1 - 0.032 14.5 0.7 0.2 11.9 0.7 2.2 1 1 0 1 1 1 0 AAA domain Sgf11 PF08209.11 EKX37862.1 - 3.7 7.2 5.3 1 9.0 1.7 1.9 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) FHA PF00498.26 EKX37864.1 - 7.9e-09 35.7 0.6 3.4e-08 33.7 0.0 2.3 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EKX37864.1 - 6.1e-07 29.7 0.0 1.9e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain NUDE_C PF04880.13 EKX37865.1 - 0.00064 20.2 4.6 1.7 9.1 4.6 2.9 1 1 0 1 1 1 1 NUDE protein, C-terminal conserved region CENP-F_leu_zip PF10473.9 EKX37865.1 - 0.18 11.8 0.8 0.21 11.6 0.8 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pkinase PF00069.25 EKX37867.1 - 4.7e-37 127.8 0.0 8e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX37867.1 - 1.8e-30 106.1 0.0 1.5e-29 103.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX37867.1 - 0.0013 18.7 0.1 0.0033 17.4 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Spc7 PF08317.11 EKX37867.1 - 0.054 12.4 4.5 0.46 9.3 2.3 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 EKX37867.1 - 0.058 12.7 2.5 0.13 11.6 2.5 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Pkinase_fungal PF17667.1 EKX37867.1 - 0.23 10.2 0.0 0.23 10.2 0.0 2.4 2 2 1 3 3 3 0 Fungal protein kinase DUF812 PF05667.11 EKX37867.1 - 0.24 10.3 8.2 0.36 9.7 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) INTS5_N PF14837.6 EKX37868.1 - 0.066 12.8 2.3 0.062 12.9 0.5 1.8 2 0 0 2 2 2 0 Integrator complex subunit 5 N-terminus HEAT_EZ PF13513.6 EKX37868.1 - 0.43 11.1 2.3 4.6 7.9 0.1 3.6 2 1 0 2 2 2 0 HEAT-like repeat HEAT PF02985.22 EKX37868.1 - 1.7 9.1 5.7 1.5 9.3 0.1 3.7 3 0 0 3 3 3 0 HEAT repeat PP2C PF00481.21 EKX37869.1 - 6.7e-72 242.2 0.8 3.5e-70 236.6 0.8 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EKX37869.1 - 1.7e-05 24.6 0.0 2.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C DNA_ligase_A_M PF01068.21 EKX37870.1 - 1.6e-58 197.8 0.0 2.4e-58 197.1 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EKX37870.1 - 6.6e-35 121.0 0.0 1.2e-34 120.2 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EKX37870.1 - 3.4e-14 53.3 0.2 5.8e-09 36.4 0.0 2.7 1 1 1 2 2 2 2 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EKX37870.1 - 0.00017 22.0 0.0 0.00031 21.1 0.0 1.5 1 0 0 1 1 1 1 RNA ligase Hyccin PF09790.9 EKX37870.1 - 0.05 12.7 0.0 0.094 11.8 0.0 1.4 1 0 0 1 1 1 0 Hyccin MSP PF01716.18 EKX37871.1 - 1.8e-96 322.0 1.6 2.2e-96 321.7 1.6 1.1 1 0 0 1 1 1 1 Manganese-stabilising protein / photosystem II polypeptide Uds1 PF15456.6 EKX37872.1 - 0.071 13.3 4.5 0.04 14.1 1.0 2.4 2 0 0 2 2 2 0 Up-regulated During Septation FGGY_C PF02782.16 EKX37874.1 - 6.7e-20 71.7 0.3 6.7e-20 71.7 0.3 2.2 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EKX37874.1 - 8.1e-12 45.2 0.0 2.1e-11 43.9 0.0 1.7 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Myb_DNA-binding PF00249.31 EKX37874.1 - 0.0026 17.9 2.4 0.005 17.0 2.4 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 EKX37874.1 - 0.085 12.9 3.1 0.22 11.6 3.1 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EKX37874.1 - 2.3 8.7 6.9 6 7.3 6.9 1.7 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Gcd10p PF04189.13 EKX37875.1 - 0.0094 15.1 2.3 0.022 13.9 2.3 1.5 1 0 0 1 1 1 1 Gcd10p family GntR PF00392.21 EKX37875.1 - 0.08 12.6 0.1 0.25 11.0 0.1 1.8 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family UPF0242 PF06785.11 EKX37875.1 - 3.4 7.7 19.7 3.6 7.6 8.2 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus MIF4G_like_2 PF09090.11 EKX37875.1 - 6.7 6.1 13.3 8 5.9 7.0 2.7 2 0 0 2 2 2 0 MIF4G like ANAPC8 PF04049.13 EKX37877.1 - 1.4e-22 80.3 5.5 5e-21 75.2 2.3 3.3 2 1 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 EKX37877.1 - 1.6e-14 53.0 20.2 0.00014 21.5 0.3 7.4 8 2 1 9 9 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 EKX37877.1 - 5.3e-14 51.1 22.5 0.0016 18.4 0.7 8.6 8 1 1 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 EKX37877.1 - 1.8e-11 43.8 17.3 0.0046 17.7 0.3 6.6 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX37877.1 - 3e-11 42.6 18.9 0.0013 18.7 0.0 7.4 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX37877.1 - 8e-10 39.2 15.7 1.4e-05 25.6 0.2 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX37877.1 - 1.6e-09 37.2 6.5 4.1e-06 26.4 0.6 3.7 3 1 1 4 4 4 2 TPR repeat TPR_19 PF14559.6 EKX37877.1 - 1.9e-07 31.5 16.0 0.19 12.3 0.2 6.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX37877.1 - 1e-05 25.7 21.1 0.0057 16.9 3.4 7.2 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX37877.1 - 3.7e-05 24.1 15.2 0.21 12.3 0.2 6.3 4 3 3 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX37877.1 - 5.3e-05 23.3 5.5 0.21 12.1 0.0 5.8 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX37877.1 - 0.0013 18.6 24.4 0.63 10.2 0.5 7.6 8 0 0 8 8 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX37877.1 - 0.0043 17.2 16.7 1 9.6 0.1 5.4 4 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EKX37877.1 - 0.0047 17.0 2.8 0.41 10.8 0.3 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX37877.1 - 0.016 15.2 0.9 0.19 11.8 0.1 3.0 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Ephrin_rec_like PF07699.13 EKX37877.1 - 0.059 13.2 24.1 0.17 11.7 6.2 3.2 3 0 0 3 3 3 0 Putative ephrin-receptor like TPR_10 PF13374.6 EKX37877.1 - 2.9 7.9 15.6 4.3 7.4 0.1 5.9 8 0 0 8 8 8 0 Tetratricopeptide repeat BCAS3 PF12490.8 EKX37879.1 - 0.00042 19.9 0.5 0.0017 17.9 0.0 2.1 2 0 0 2 2 2 1 Breast carcinoma amplified sequence 3 WD40 PF00400.32 EKX37879.1 - 0.029 15.2 4.3 1.6 9.7 0.0 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat IP_trans PF02121.18 EKX37883.1 - 3.6e-84 282.2 1.0 4.5e-84 281.9 1.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein DUF3337 PF11816.8 EKX37883.1 - 0.0063 16.4 0.0 0.0093 15.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) Peptidase_M6 PF05547.11 EKX37883.1 - 0.055 11.8 0.0 0.072 11.4 0.0 1.1 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 Nic96 PF04097.14 EKX37884.1 - 1.4e-11 43.6 0.6 1.7e-06 26.9 0.0 2.6 3 0 0 3 3 3 2 Nup93/Nic96 KH_1 PF00013.29 EKX37885.1 - 2.6e-13 49.6 0.0 3.7e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 EKX37885.1 - 0.025 14.4 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 KH domain PKD_channel PF08016.12 EKX37886.1 - 2e-37 128.9 1.0 3.2e-37 128.2 1.0 1.3 1 0 0 1 1 1 1 Polycystin cation channel MORN PF02493.20 EKX37887.1 - 1.6e-43 144.0 95.4 1.6e-06 27.7 2.3 17.5 18 0 0 18 18 18 15 MORN repeat DUF1419 PF07215.11 EKX37887.1 - 0.64 10.1 1.9 24 5.1 0.0 3.9 4 1 1 5 5 5 0 Protein of unknown function (DUF1419) Beta_helix PF13229.6 EKX37888.1 - 0.00071 19.5 0.0 0.00088 19.1 0.0 1.1 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 EKX37888.1 - 0.0022 17.3 0.0 0.0028 17.0 0.0 1.1 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Phage_Coat_B PF05356.11 EKX37888.1 - 0.035 14.0 0.4 0.066 13.1 0.4 1.4 1 0 0 1 1 1 0 Phage Coat protein B RWP-RK PF02042.15 EKX37889.1 - 5.8e-14 51.8 0.0 9.6e-14 51.1 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain TFB6 PF17110.5 EKX37889.1 - 0.15 11.8 0.5 0.24 11.1 0.5 1.4 1 1 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH zf-ANAPC11 PF12861.7 EKX37890.1 - 2.7e-37 126.7 13.3 2.9e-37 126.6 13.3 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EKX37890.1 - 1.7e-20 73.0 14.0 2.3e-20 72.6 14.0 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EKX37890.1 - 5.5e-05 23.4 19.5 0.0018 18.6 19.5 2.6 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX37890.1 - 0.017 14.9 6.2 0.017 14.9 6.2 2.7 1 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 EKX37890.1 - 0.16 11.8 5.4 0.24 11.2 5.4 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Cys_Knot_tox PF17486.2 EKX37890.1 - 0.34 11.2 12.3 0.053 13.8 7.7 2.0 1 1 1 2 2 2 0 Cystine knot toxins zf-C3HC4 PF00097.25 EKX37890.1 - 0.38 10.7 17.8 3.2 7.7 17.8 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX37890.1 - 0.74 9.8 15.2 20 5.2 16.1 2.5 1 1 1 2 2 2 0 zinc-RING finger domain Rad50_zn_hook PF04423.14 EKX37890.1 - 0.85 9.5 3.6 2.7 7.9 0.0 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 EKX37890.1 - 1.4 8.8 17.9 0.11 12.3 3.0 2.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 EKX37890.1 - 2.6 7.9 15.8 11 6.0 11.8 2.6 1 1 2 3 3 3 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EKX37890.1 - 7 6.9 14.9 67 3.8 14.9 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain Chorein_N PF12624.7 EKX37891.1 - 3e-10 40.2 0.0 1.5e-08 34.7 0.0 2.9 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 DUF745 PF05335.13 EKX37891.1 - 0.38 10.4 6.6 0.87 9.3 6.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) WD40 PF00400.32 EKX37892.1 - 3.1e-39 132.3 27.3 5.6e-05 23.8 0.0 12.0 12 0 0 12 12 12 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX37892.1 - 3.4e-14 52.9 1.8 0.056 13.7 0.0 7.1 5 2 2 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EKX37892.1 - 3.9e-05 24.0 2.0 0.98 10.0 0.2 5.3 4 0 0 4 4 4 1 PQQ-like domain PQQ_2 PF13360.6 EKX37892.1 - 0.0077 15.8 0.0 0.25 10.9 0.0 3.2 2 1 1 3 3 3 1 PQQ-like domain PALB2_WD40 PF16756.5 EKX37892.1 - 0.032 13.2 0.1 8.3 5.2 0.0 2.7 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Aldo_ket_red PF00248.21 EKX37893.1 - 1.5e-24 86.7 0.0 2e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family TAT_signal PF10518.9 EKX37893.1 - 0.0048 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Sacchrp_dh_NADP PF03435.18 EKX37893.1 - 0.064 13.5 0.0 4.1 7.7 0.0 2.4 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain JAB PF01398.21 EKX37894.1 - 4.8e-25 87.8 0.0 5.5e-25 87.6 0.0 1.0 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EKX37894.1 - 4.2e-10 39.4 0.2 4.8e-10 39.2 0.2 1.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain FA_desaturase PF00487.24 EKX37895.1 - 5.8e-08 32.9 20.1 2.8e-06 27.4 12.6 2.1 2 0 0 2 2 2 2 Fatty acid desaturase Ion_trans PF00520.31 EKX37896.1 - 5e-131 435.3 76.2 2.5e-41 141.6 7.7 4.2 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 EKX37896.1 - 2.1e-07 30.0 59.7 1.7e-05 23.7 13.8 5.9 6 0 0 6 6 6 4 Polycystin cation channel Thoc2 PF11732.8 EKX37896.1 - 0.081 13.0 0.0 0.35 11.0 0.0 2.1 1 0 0 1 1 1 0 Transcription- and export-related complex subunit zf-RING_2 PF13639.6 EKX37897.1 - 4.9e-12 46.0 8.7 1.1e-11 44.9 8.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EKX37897.1 - 1.3e-08 34.4 4.3 1.3e-08 34.4 4.3 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 EKX37897.1 - 1.2e-07 31.9 5.9 3.1e-07 30.6 5.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EKX37897.1 - 7.1e-07 29.0 8.7 9.3e-07 28.6 7.5 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX37897.1 - 4.5e-06 26.5 6.8 1.5e-05 24.8 6.8 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EKX37897.1 - 6.4e-06 26.1 6.2 2.2e-05 24.4 6.3 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EKX37897.1 - 1.1e-05 25.1 8.2 3.7e-05 23.5 8.2 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EKX37897.1 - 6.1e-05 22.8 9.8 0.00011 21.9 9.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EKX37897.1 - 0.00025 21.0 5.4 0.00099 19.1 5.4 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EKX37897.1 - 0.002 18.0 9.6 0.0056 16.5 9.6 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 RINGv PF12906.7 EKX37897.1 - 0.0024 18.0 3.8 0.0072 16.4 3.8 1.9 1 1 0 1 1 1 1 RING-variant domain zf-C3HC4_4 PF15227.6 EKX37897.1 - 0.044 13.9 4.9 0.14 12.3 4.9 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 EKX37897.1 - 0.11 12.1 8.1 0.12 12.0 6.3 1.9 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EKX37897.1 - 0.18 12.0 7.5 0.53 10.5 7.5 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 EKX37897.1 - 0.56 10.1 5.8 0.96 9.4 5.3 1.7 1 1 0 1 1 1 0 PHD-finger zf-Nse PF11789.8 EKX37897.1 - 0.73 9.7 6.4 1.3 8.9 4.0 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit UBZ_FAAP20 PF15750.5 EKX37897.1 - 4.4 7.3 6.6 23 5.1 3.1 2.4 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger TCR PF03638.15 EKX37899.1 - 9.9e-27 93.0 53.6 1.8e-13 50.6 22.4 2.1 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain Osmo_MPGsynth PF09488.10 EKX37899.1 - 0.095 11.4 0.1 0.77 8.4 0.0 1.9 2 0 0 2 2 2 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) MutS_V PF00488.21 EKX37901.1 - 1.9e-42 145.4 0.0 3.3e-42 144.6 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 EKX37901.1 - 1.4e-13 51.0 0.0 3.7e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 MutS domain I AAA_23 PF13476.6 EKX37901.1 - 0.001 19.6 0.4 0.0041 17.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EKX37901.1 - 0.0037 17.0 0.1 0.0098 15.6 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.6 EKX37901.1 - 0.046 13.7 0.0 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EKX37901.1 - 0.095 13.2 0.1 0.25 11.8 0.1 1.7 1 0 0 1 1 1 0 ABC transporter AAA_27 PF13514.6 EKX37901.1 - 0.18 11.4 0.0 0.39 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Chorion_2 PF03964.15 EKX37901.1 - 0.22 12.4 4.3 0.55 11.1 4.3 1.7 1 0 0 1 1 1 0 Chorion family 2 RAP1 PF07218.11 EKX37901.1 - 0.94 7.7 7.7 1.3 7.2 7.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) 4HBT PF03061.22 EKX37902.1 - 8.4e-09 35.7 0.0 2.4e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 Thioesterase superfamily MFS_1 PF07690.16 EKX37902.1 - 4.7e-07 29.0 39.3 1.6e-05 24.1 21.2 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Collagen PF01391.18 EKX37903.1 - 5.8e-08 32.4 28.3 1e-07 31.6 28.3 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) PKD_channel PF08016.12 EKX37904.1 - 6.1e-19 68.0 7.4 6.1e-19 68.0 7.4 3.2 1 1 1 2 2 2 1 Polycystin cation channel DUF1189 PF06691.11 EKX37904.1 - 0.0016 18.1 2.1 0.0016 18.1 2.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1189) Colipase_C PF02740.14 EKX37904.1 - 0.013 15.7 0.4 0.025 14.7 0.4 1.4 1 0 0 1 1 1 0 Colipase, C-terminal domain ASC PF00858.24 EKX37904.1 - 0.28 10.1 1.2 0.53 9.2 1.2 1.4 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel hnRNP_Q_AcD PF18360.1 EKX37905.1 - 5.8e-16 58.2 0.0 3.1e-10 39.9 0.0 2.2 2 0 0 2 2 2 2 Heterogeneous nuclear ribonucleoprotein Q acidic domain zf-CCHC PF00098.23 EKX37905.1 - 4.8e-05 23.2 0.8 9.9e-05 22.2 0.8 1.5 1 0 0 1 1 1 1 Zinc knuckle Nop14 PF04147.12 EKX37905.1 - 0.0044 15.3 8.3 0.0044 15.3 8.3 3.0 3 0 0 3 3 3 2 Nop14-like family DUF5422 PF17459.2 EKX37905.1 - 0.14 12.3 0.0 1.8 8.7 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5422) zf-TFIIB PF13453.6 EKX37905.1 - 0.14 11.5 1.1 0.25 10.7 1.1 1.4 1 0 0 1 1 1 0 Transcription factor zinc-finger zf-CCHC_4 PF14392.6 EKX37905.1 - 0.26 11.1 1.2 0.46 10.3 1.2 1.4 1 0 0 1 1 1 0 Zinc knuckle Sigma70_ner PF04546.13 EKX37905.1 - 0.49 10.2 33.7 2.6 7.9 3.4 3.2 3 0 0 3 3 3 0 Sigma-70, non-essential region SOG2 PF10428.9 EKX37905.1 - 0.53 9.4 9.0 1.7 7.8 2.7 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein DUF2981 PF11200.8 EKX37905.1 - 3.5 7.3 4.1 17 5.1 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) IQ PF00612.27 EKX37907.1 - 3.9e-30 100.8 22.4 7e-05 22.3 0.2 6.9 6 0 0 6 6 6 6 IQ calmodulin-binding motif WW PF00397.26 EKX37907.1 - 1.3e-06 28.4 3.6 2.6e-06 27.4 3.6 1.5 1 0 0 1 1 1 1 WW domain Glyco_hyd_101C PF17451.2 EKX37907.1 - 0.014 15.7 0.5 0.08 13.2 0.5 2.4 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain DUF1338 PF07063.13 EKX37908.1 - 8.2e-31 107.4 0.2 5.9e-29 101.3 0.2 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF1338) RsbU_N PF08673.10 EKX37910.1 - 0.015 15.4 0.2 0.036 14.2 0.2 1.7 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain Baculo_PEP_C PF04513.12 EKX37910.1 - 0.52 10.3 2.8 1.5 8.8 0.3 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MFS_1 PF07690.16 EKX37912.1 - 2.4e-06 26.7 49.4 9.1e-05 21.5 19.5 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EKX37912.1 - 0.36 9.6 11.4 0.09 11.6 5.1 2.3 2 0 0 2 2 2 0 MFS_1 like family AMP-binding PF00501.28 EKX37913.1 - 1.3e-25 89.9 0.0 1.6e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF1216 PF06746.11 EKX37914.1 - 0.0082 16.2 1.4 0.011 15.7 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1216) BicD PF09730.9 EKX37914.1 - 0.015 13.8 14.4 0.02 13.4 14.4 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D ERM PF00769.19 EKX37914.1 - 0.93 9.3 22.1 1.1 9.0 22.1 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family AATF-Che1 PF13339.6 EKX37914.1 - 1.1 10.0 5.0 2.5 8.8 5.0 1.7 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Ank_2 PF12796.7 EKX37915.1 - 3e-31 107.8 0.4 6.4e-13 49.1 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX37915.1 - 1.6e-18 66.8 0.1 0.00011 22.6 0.0 3.9 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX37915.1 - 3.5e-16 57.7 0.3 0.003 17.9 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 EKX37915.1 - 7.2e-15 54.7 0.9 0.013 15.9 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EKX37915.1 - 5.9e-11 42.4 2.1 0.014 15.7 0.1 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Kinesin PF00225.23 EKX37917.1 - 8.8e-103 343.7 0.1 1.1e-102 343.4 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX37917.1 - 7.7e-25 87.6 0.0 1.4e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding DUF4839 PF16127.5 EKX37917.1 - 0.02 15.0 0.0 2.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4839) AAA_18 PF13238.6 EKX37919.1 - 1.6e-07 32.0 0.0 3.9e-07 30.7 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 EKX37919.1 - 1.8e-05 24.9 0.0 4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EKX37919.1 - 0.00086 18.6 0.0 0.0017 17.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain SKI PF01202.22 EKX37919.1 - 0.00089 19.4 0.0 0.0077 16.4 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase AAA_28 PF13521.6 EKX37919.1 - 0.0036 17.6 0.3 0.018 15.3 0.1 2.0 1 1 1 2 2 2 1 AAA domain DUF1298 PF06974.13 EKX37919.1 - 0.027 14.4 0.1 0.091 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1298) AAA_16 PF13191.6 EKX37919.1 - 0.029 14.7 0.1 0.057 13.8 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 EKX37919.1 - 0.048 13.7 0.1 0.18 11.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 EKX37919.1 - 0.073 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Cytidylate_kin PF02224.18 EKX37919.1 - 0.084 12.6 0.0 0.25 11.1 0.0 1.8 2 1 0 2 2 2 0 Cytidylate kinase KTI12 PF08433.10 EKX37919.1 - 0.093 12.2 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA PF00004.29 EKX37919.1 - 0.12 12.8 0.0 0.33 11.4 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EKX37919.1 - 0.15 11.3 0.0 0.96 8.7 0.0 2.2 1 1 0 1 1 1 0 Zeta toxin HALZ PF02183.18 EKX37920.1 - 0.047 13.9 6.3 1.3 9.3 0.2 3.2 3 1 0 3 3 3 0 Homeobox associated leucine zipper DUF4706 PF15797.5 EKX37920.1 - 0.52 10.9 5.3 0.31 11.6 1.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4706) DivIVA PF05103.13 EKX37920.1 - 3.9 7.6 15.5 8.5 6.5 1.1 3.7 1 1 3 4 4 4 0 DivIVA protein FUSC PF04632.12 EKX37920.1 - 5.1 5.5 6.4 5.9 5.3 6.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family MnmE_helical PF12631.7 EKX37920.1 - 6.1 7.0 7.5 2.3 8.3 3.4 2.1 1 1 1 2 2 2 0 MnmE helical domain Pkinase PF00069.25 EKX37921.1 - 6.2e-67 225.7 0.0 7e-67 225.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX37921.1 - 6.5e-35 120.7 0.0 7.8e-35 120.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX37921.1 - 1.4e-07 31.1 0.3 1.3e-06 28.0 0.1 2.4 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EKX37921.1 - 8.5e-06 24.9 0.0 1.1e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EKX37921.1 - 1.7e-05 24.8 0.1 2.5e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX37921.1 - 0.00031 20.1 0.3 0.00061 19.2 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EKX37921.1 - 0.00098 18.8 0.0 1.2 8.7 0.0 2.5 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EKX37921.1 - 0.061 12.9 0.1 0.13 11.8 0.0 1.5 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 EKX37921.1 - 0.072 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PEP_mutase PF13714.6 EKX37925.1 - 1e-23 84.1 0.0 1.1e-23 84.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EKX37925.1 - 1.4e-05 23.8 0.1 1.5e-05 23.7 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Asparaginase_2 PF01112.18 EKX37926.1 - 1.5e-54 185.1 0.9 6.2e-53 179.8 0.9 2.0 1 1 1 2 2 2 2 Asparaginase PDZ_2 PF13180.6 EKX37927.1 - 9.2e-05 22.7 0.2 0.00029 21.1 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EKX37927.1 - 0.0013 18.6 0.6 0.0046 16.8 0.2 2.4 2 1 0 2 2 2 1 PDZ domain Keratin_2_head PF16208.5 EKX37927.1 - 0.0046 17.1 2.5 0.0079 16.3 2.5 1.3 1 0 0 1 1 1 1 Keratin type II head AsnC_trans_reg PF01037.21 EKX37927.1 - 0.044 13.7 1.5 0.075 13.0 0.1 2.2 2 0 0 2 2 2 0 Lrp/AsnC ligand binding domain PDZ PF00595.24 EKX37927.1 - 0.093 13.1 0.0 0.48 10.8 0.0 2.3 2 0 0 2 2 2 0 PDZ domain KRTAP PF11759.8 EKX37927.1 - 1.1 9.9 9.0 1.8 9.2 9.0 1.2 1 0 0 1 1 1 0 Keratin-associated matrix C2 PF00168.30 EKX37928.1 - 2.4e-21 76.0 0.0 2.6e-21 75.8 0.0 1.0 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.6 EKX37929.1 - 5.5e-19 68.4 1.6 5.6e-18 65.2 0.9 2.1 1 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX37929.1 - 6.8e-19 65.9 5.2 2.2e-08 33.0 0.5 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EKX37929.1 - 4.9e-17 60.3 2.1 1.9e-07 30.4 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 EKX37929.1 - 4.6e-15 55.2 9.1 4.2e-12 45.7 1.2 3.0 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX37929.1 - 5.1e-15 54.2 3.3 9.5e-07 28.1 0.4 2.6 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 EKX37929.1 - 9.7e-05 22.3 3.9 0.16 11.9 0.3 2.9 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EKX37929.1 - 0.0031 17.8 0.1 0.0052 17.1 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain PheRS_DBD2 PF18554.1 EKX37929.1 - 0.0051 16.8 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 PheRS DNA binding domain 2 Dockerin_1 PF00404.18 EKX37929.1 - 0.028 14.6 1.5 2.8 8.2 0.0 2.3 2 0 0 2 2 2 0 Dockerin type I domain Toprim PF01751.22 EKX37929.1 - 0.08 13.2 0.0 0.099 12.9 0.0 1.2 1 0 0 1 1 1 0 Toprim domain SPARC_Ca_bdg PF10591.9 EKX37929.1 - 0.093 13.1 0.1 0.17 12.2 0.1 1.6 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3944 PF13099.6 EKX37929.1 - 0.099 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) ArgJ PF01960.18 EKX37929.1 - 0.1 11.3 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 ArgJ family CrgA PF06781.12 EKX37930.1 - 0.034 14.2 1.5 0.064 13.3 0.0 2.2 2 0 0 2 2 2 0 Cell division protein CrgA DUF3007 PF11460.8 EKX37931.1 - 4.5e-24 84.5 0.1 5.3e-24 84.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3007) DUF3067 PF11267.8 EKX37932.1 - 1.4e-26 93.0 0.0 2.2e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3067) Pneumo_matrix PF03393.16 EKX37932.1 - 0.15 11.3 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Pneumovirus matrix protein DUF908 PF06012.12 EKX37934.1 - 1.3 8.3 5.6 1.5 8.1 5.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) GvpO PF05800.11 EKX37934.1 - 4.8 7.2 6.3 6.7 6.8 3.6 2.6 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpO PH PF00169.29 EKX37937.1 - 3.4e-13 50.0 0.0 4.2e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 PH domain PH_6 PF15406.6 EKX37937.1 - 5.4e-05 23.4 0.0 7.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 EKX37937.1 - 0.0081 16.6 0.1 0.049 14.1 0.1 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 EKX37937.1 - 0.0083 16.5 0.0 0.025 15.0 0.0 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_16 PF17838.1 EKX37937.1 - 0.013 15.4 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 PH domain Bunya_NS-S PF01104.17 EKX37938.1 - 0.44 10.4 3.6 0.28 11.0 0.6 2.1 2 0 0 2 2 2 0 Bunyavirus non-structural protein NS-s YL1_C PF08265.11 EKX37939.1 - 7.4e-13 48.0 0.1 1.1e-12 47.5 0.1 1.2 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DUF722 PF05263.11 EKX37939.1 - 0.075 13.3 0.3 0.098 12.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF722) DSPc PF00782.20 EKX37940.1 - 4.6e-20 71.8 0.0 7.6e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EKX37940.1 - 0.00032 20.8 0.0 0.00055 20.1 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.12 EKX37940.1 - 0.0044 16.7 0.0 0.0074 16.0 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 EKX37940.1 - 0.0083 15.7 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Phage_holin_3_1 PF05106.12 EKX37940.1 - 0.088 13.2 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) Rhodanese PF00581.20 EKX37940.1 - 0.19 12.3 0.0 0.37 11.3 0.0 1.5 1 0 0 1 1 1 0 Rhodanese-like domain Ank PF00023.30 EKX37941.1 - 1.2e-07 31.8 0.1 0.00031 21.1 0.2 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EKX37941.1 - 2.7e-06 27.9 0.0 0.00012 22.6 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX37941.1 - 7.7e-06 26.4 0.4 0.00048 20.6 0.3 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX37941.1 - 9.3e-06 25.8 0.4 2.9e-05 24.2 0.5 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) YppG PF14179.6 EKX37941.1 - 0.05 14.3 2.8 0.057 14.1 0.0 2.4 2 0 0 2 2 2 0 YppG-like protein ESR1_C PF12743.7 EKX37941.1 - 0.079 12.7 0.4 0.19 11.6 0.4 1.6 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal AIM5 PF17050.5 EKX37941.1 - 0.22 12.3 2.4 1 10.2 2.4 2.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria 5 Glycos_transf_2 PF00535.26 EKX37942.1 - 1.9e-07 31.1 0.1 0.0065 16.3 0.0 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_4 PF13704.6 EKX37942.1 - 0.00017 22.1 0.0 0.00052 20.5 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EKX37942.1 - 0.042 13.7 0.0 0.42 10.5 0.0 2.3 3 0 0 3 3 3 0 Glycosyltransferase like family 2 Helicase_C PF00271.31 EKX37947.1 - 3e-16 59.7 0.0 3.8e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EKX37947.1 - 0.0051 16.1 0.1 0.01 15.1 0.0 1.6 1 1 1 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase SNF2_N PF00176.23 EKX37948.1 - 2.8e-32 111.8 0.1 3.1e-32 111.7 0.1 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain SWI2_SNF2 PF18766.1 EKX37948.1 - 0.0031 17.2 0.0 0.0039 16.9 0.0 1.2 1 0 0 1 1 1 1 SWI2/SNF2 ATPase ResIII PF04851.15 EKX37948.1 - 0.02 14.9 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Misat_Tub_SegII PF10644.9 EKX37949.1 - 0.039 14.2 0.0 0.086 13.1 0.0 1.6 1 1 0 1 1 1 0 Misato Segment II tubulin-like domain DUF1828 PF08861.10 EKX37949.1 - 0.077 13.3 0.0 0.34 11.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF1828 Hydrolase_4 PF12146.8 EKX37951.1 - 7.5e-06 25.4 0.0 0.0013 18.0 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EKX37951.1 - 0.00016 22.3 0.0 0.00035 21.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EKX37951.1 - 0.099 12.3 0.0 1.4 8.5 0.0 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold FKBP_C PF00254.28 EKX37952.1 - 1.6e-09 37.9 0.0 2.7e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase 2C_adapt PF08793.10 EKX37952.1 - 0.012 15.8 0.1 0.022 15.0 0.1 1.4 1 0 0 1 1 1 0 2-cysteine adaptor domain Ribosomal_TL5_C PF14693.6 EKX37954.1 - 6.9e-18 64.8 0.0 1.3e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain Ribosomal_L25p PF01386.19 EKX37954.1 - 4.9e-05 23.8 0.0 0.00011 22.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal L25p family Peptidase_C34 PF05413.11 EKX37954.1 - 0.11 12.7 0.1 0.44 10.8 0.0 1.9 2 0 0 2 2 2 0 Putative closterovirus papain-like endopeptidase Pkinase PF00069.25 EKX37955.1 - 2e-40 138.9 0.0 2.2e-40 138.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX37955.1 - 1.8e-27 96.3 0.0 2e-27 96.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX37955.1 - 6.4e-05 23.0 0.0 0.0001 22.3 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EKX37955.1 - 0.031 13.8 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 EKX37955.1 - 0.06 12.4 0.1 0.1 11.7 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 EKX37955.1 - 0.1 12.2 0.0 0.25 11.0 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 ABC1 PF03109.16 EKX37955.1 - 0.17 12.0 0.0 0.39 10.9 0.0 1.5 1 1 0 1 1 1 0 ABC1 family CENP-T_C PF15511.6 EKX37956.1 - 4.1e-09 36.5 0.1 5e-09 36.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EKX37956.1 - 0.0001 22.6 0.1 0.00014 22.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 EKX37956.1 - 0.0001 22.4 0.2 0.00014 21.9 0.2 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 EKX37956.1 - 0.00021 21.7 0.3 0.00024 21.5 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EKX37956.1 - 0.00042 20.5 0.1 0.00064 19.9 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EKX37956.1 - 0.0073 16.4 0.0 0.0085 16.2 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EKX37956.1 - 0.013 15.5 0.1 0.02 14.9 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated Apt1 PF10351.9 EKX37957.1 - 4.9e-24 85.0 0.2 1.6e-23 83.3 0.2 1.9 1 0 0 1 1 1 1 Golgi-body localisation protein domain DEP PF00610.21 EKX37957.1 - 1.6e-15 56.9 0.1 1.2e-14 54.1 0.0 2.6 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Fmp27_GFWDK PF10347.9 EKX37957.1 - 3.4e-12 46.8 0.0 4.5e-11 43.1 0.0 2.3 1 1 1 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 EKX37957.1 - 1.2e-06 28.5 0.0 2.8e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) UNC-79 PF14776.6 EKX37957.1 - 0.15 10.8 0.1 0.25 10.1 0.1 1.2 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 PAXIP1_C PF15364.6 EKX37957.1 - 2.6 8.4 9.6 4.2 7.7 0.2 3.7 3 0 0 3 3 3 0 PAXIP1-associated-protein-1 C term PTIP binding protein CEBP_ZZ PF16366.5 EKX37958.1 - 0.077 13.2 6.0 0.12 12.6 6.0 1.3 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Ribosomal_L44 PF00935.19 EKX37958.1 - 0.091 13.3 9.4 0.036 14.6 6.2 1.9 2 0 0 2 2 2 0 Ribosomal protein L44 PolC_DP2 PF03833.13 EKX37958.1 - 0.22 9.3 3.3 0.25 9.1 3.3 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 PRP3 PF08572.10 EKX37958.1 - 4.1 7.1 9.3 1.4 8.6 0.5 2.0 1 1 1 2 2 2 0 pre-mRNA processing factor 3 (PRP3) LRR_8 PF13855.6 EKX37959.1 - 8.6e-48 159.9 28.9 1.1e-16 60.3 2.9 4.1 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EKX37959.1 - 1.1e-18 67.0 17.0 3.6e-05 24.0 0.4 4.5 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX37959.1 - 2.3e-17 63.2 0.0 6.4e-10 39.1 0.0 2.1 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EKX37959.1 - 2.3e-10 39.6 9.7 0.16 12.7 0.1 6.7 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_9 PF14580.6 EKX37959.1 - 1.8e-09 37.4 1.8 1.3e-05 24.8 0.5 2.8 1 1 2 3 3 3 3 Leucine-rich repeat LRR_2 PF07723.13 EKX37959.1 - 0.24 12.2 9.9 13 6.7 0.0 5.8 7 0 0 7 7 7 0 Leucine Rich Repeat GTP_cyclohydroI PF01227.22 EKX37961.1 - 7.4e-77 256.8 0.2 8.5e-77 256.6 0.2 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EKX37961.1 - 0.0072 16.5 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 QueF-like protein RWP-RK PF02042.15 EKX37965.1 - 4.3e-13 49.0 0.1 6.6e-13 48.4 0.1 1.2 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX37966.1 - 4.3e-13 49.0 0.1 6.6e-13 48.4 0.1 1.2 1 0 0 1 1 1 1 RWP-RK domain Ras PF00071.22 EKX37967.1 - 6.5e-67 224.2 0.7 7.5e-67 224.0 0.7 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EKX37967.1 - 1e-35 122.5 0.2 1.7e-35 121.8 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EKX37967.1 - 2.7e-15 56.2 0.2 3.3e-15 56.0 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EKX37967.1 - 4.7e-07 29.5 0.3 1.2e-06 28.2 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EKX37967.1 - 1.6e-06 27.7 0.3 2.2e-06 27.2 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EKX37967.1 - 1e-05 25.6 0.2 3.4e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EKX37967.1 - 1.7e-05 24.8 0.5 0.17 11.8 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EKX37967.1 - 0.00068 19.1 0.1 0.00084 18.8 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EKX37967.1 - 0.0033 17.0 0.1 0.019 14.5 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B G-alpha PF00503.20 EKX37967.1 - 0.0044 16.2 5.0 0.027 13.6 1.4 2.6 1 1 1 2 2 2 1 G-protein alpha subunit ATP_bind_1 PF03029.17 EKX37967.1 - 0.018 14.8 0.1 0.052 13.3 0.0 1.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 EKX37967.1 - 0.023 14.4 0.6 0.26 11.1 0.6 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EKX37967.1 - 0.025 15.0 0.0 0.032 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EKX37967.1 - 0.025 15.0 0.7 1.8 9.0 0.1 2.9 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 EKX37967.1 - 0.039 13.2 0.6 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_29 PF13555.6 EKX37967.1 - 0.049 13.4 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EKX37967.1 - 0.074 13.3 0.2 0.39 11.0 0.1 2.1 1 1 0 1 1 1 0 AAA domain PQQ_2 PF13360.6 EKX37968.1 - 0.00027 20.6 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 PQQ-like domain PQQ_3 PF13570.6 EKX37968.1 - 0.024 15.1 0.0 19 5.9 0.0 3.4 2 1 0 2 2 2 0 PQQ-like domain Glyco_transf_41 PF13844.6 EKX37969.1 - 2.5e-22 79.0 0.0 8.4e-11 41.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 41 PAS_8 PF13188.7 EKX37969.1 - 0.16 12.1 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 PAS domain RWP-RK PF02042.15 EKX37970.1 - 3.6e-14 52.5 0.1 5.5e-14 51.9 0.1 1.2 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX37970.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Ran_BP1 PF00638.18 EKX37971.1 - 1.7e-38 131.7 0.7 2.6e-38 131.0 0.7 1.2 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 EKX37971.1 - 0.006 16.5 0.7 0.15 12.0 0.7 2.1 1 1 0 1 1 1 1 WH1 domain PDZ_6 PF17820.1 EKX37972.1 - 2.6e-09 36.8 0.0 3.6e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX37972.1 - 3.1e-09 37.0 0.0 5.1e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX37972.1 - 4.5e-07 30.1 0.0 6.5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX37972.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.5 1 1 0 1 1 1 0 Tricorn protease PDZ domain ATP-grasp_2 PF08442.10 EKX37973.1 - 8.6e-67 224.6 1.4 1.2e-66 224.1 1.4 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 EKX37973.1 - 8.5e-23 80.9 0.2 1.8e-22 79.8 0.2 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EKX37973.1 - 5.6e-10 39.1 1.2 1.2e-09 38.0 1.2 1.6 1 1 0 1 1 1 1 ATP-grasp domain Citrate_bind PF16114.5 EKX37973.1 - 2.3e-05 24.0 0.0 4.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding GARS_A PF01071.19 EKX37973.1 - 0.00029 20.7 0.7 0.0017 18.2 0.1 2.1 1 1 1 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain LRR_4 PF12799.7 EKX37974.1 - 1.2e-09 38.2 10.8 0.0013 19.1 0.9 4.5 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX37974.1 - 1e-07 31.6 16.9 4.2e-05 23.2 0.7 4.9 5 0 0 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 EKX37974.1 - 3.6 8.5 8.5 37 5.4 0.2 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat Ubiquitin_2 PF14560.6 EKX37975.1 - 0.0043 17.5 0.4 0.049 14.1 0.0 2.6 3 0 0 3 3 3 1 Ubiquitin-like domain Arf PF00025.21 EKX37975.1 - 0.018 14.5 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family ubiquitin PF00240.23 EKX37976.1 - 5.2e-29 99.8 0.1 5.8e-29 99.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EKX37976.1 - 1.8e-17 62.9 0.1 2e-17 62.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EKX37976.1 - 4.9e-05 23.7 0.1 0.00018 21.9 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EKX37976.1 - 0.00042 20.2 0.0 0.00052 19.9 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EKX37976.1 - 0.0027 17.8 0.1 0.0087 16.2 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 EKX37976.1 - 0.075 13.1 0.5 3 7.9 0.2 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain TF_Zn_Ribbon PF08271.12 EKX37977.1 - 0.13 11.8 1.6 4.1 7.0 0.1 2.4 2 1 0 2 2 2 0 TFIIB zinc-binding Zn_ribbon_SprT PF17283.2 EKX37977.1 - 0.13 12.2 4.6 0.46 10.4 0.6 2.1 2 0 0 2 2 2 0 SprT-like zinc ribbon domain Rubredoxin PF00301.20 EKX37977.1 - 0.21 11.6 11.7 0.23 11.5 6.4 2.7 2 1 0 2 2 2 0 Rubredoxin Gram_pos_anchor PF00746.21 EKX37977.1 - 0.24 11.4 1.9 0.42 10.6 1.9 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif zf-tcix PF14952.6 EKX37977.1 - 0.3 10.8 2.1 3.2 7.5 0.1 2.2 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Prim_Zn_Ribbon PF08273.12 EKX37977.1 - 1.1 9.6 6.0 1.6 9.1 0.2 2.2 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase UPF0547 PF10571.9 EKX37977.1 - 3.1 8.0 8.2 3.7 7.7 0.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 CitMHS PF03600.16 EKX37978.1 - 2.7e-23 82.6 22.8 2.7e-23 82.6 22.8 1.4 2 0 0 2 2 2 1 Citrate transporter Bromodomain PF00439.25 EKX37979.1 - 3.8e-17 62.1 0.0 5e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Bromodomain RE_NgoPII PF09521.10 EKX37979.1 - 0.15 11.2 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 NgoPII restriction endonuclease Metallophos PF00149.28 EKX37980.1 - 2.9e-28 99.8 0.3 3.6e-28 99.5 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase V-SNARE_C PF12352.8 EKX37981.1 - 3.6e-07 30.4 3.6 7.8e-07 29.3 0.5 2.4 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EKX37981.1 - 0.0027 17.6 0.4 0.037 13.9 0.1 2.3 2 0 0 2 2 2 1 Sec20 DUF3584 PF12128.8 EKX37981.1 - 0.0034 15.0 0.8 0.0038 14.8 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Mce4_CUP1 PF11887.8 EKX37981.1 - 0.015 14.7 0.9 0.035 13.5 0.0 1.8 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF5113 PF17140.4 EKX37981.1 - 0.042 13.6 0.1 0.062 13.1 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5113) FliD_N PF02465.18 EKX37981.1 - 0.05 14.3 0.3 4.4 8.1 0.1 2.5 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus TPR_MLP1_2 PF07926.12 EKX37981.1 - 0.064 13.3 2.5 0.076 13.1 0.8 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Adenylsucc_synt PF00709.21 EKX37981.1 - 0.11 11.4 0.1 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 Adenylosuccinate synthetase Exonuc_VII_L PF02601.15 EKX37981.1 - 0.17 11.4 2.6 0.22 11.0 2.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit EpmC PF04315.12 EKX37982.1 - 0.00035 20.3 0.0 0.00059 19.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P hydroxylase Pkinase_Tyr PF07714.17 EKX37983.1 - 9.1e-69 231.6 0.0 1e-68 231.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX37983.1 - 3.4e-34 118.4 0.0 4e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain DDE_Tnp_1_7 PF13843.6 EKX37993.1 - 1.8e-17 63.7 0.0 2.1e-17 63.5 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 ABC_membrane_3 PF13748.6 EKX37994.1 - 0.045 13.0 0.1 0.065 12.5 0.1 1.1 1 0 0 1 1 1 0 ABC transporter transmembrane region DUF1997 PF09366.10 EKX37995.1 - 4.4e-21 75.6 0.1 5.6e-21 75.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1997) DnaB PF00772.21 EKX37996.1 - 0.00014 21.9 0.0 0.00031 20.8 0.0 1.6 1 0 0 1 1 1 1 DnaB-like helicase N terminal domain SQS_PSY PF00494.19 EKX37996.1 - 0.1 12.1 1.1 3.5 7.0 0.0 2.6 2 1 0 2 2 2 0 Squalene/phytoene synthase cNMP_binding PF00027.29 EKX37997.1 - 4e-08 33.2 0.3 1e-06 28.7 0.3 2.3 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain CRAL_TRIO PF00650.20 EKX38001.1 - 9.7e-21 74.1 0.0 6.7e-20 71.4 0.0 2.0 2 0 0 2 2 2 1 CRAL/TRIO domain COX8 PF02285.15 EKX38001.1 - 0.16 11.9 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIII zf-RING_7 PF02591.15 EKX38001.1 - 9.7 6.5 9.4 5 7.4 0.0 3.6 3 0 0 3 3 3 0 C4-type zinc ribbon domain Ank_4 PF13637.6 EKX38002.1 - 2.6e-36 123.5 7.8 4e-11 43.2 0.0 6.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX38002.1 - 2.4e-30 105.0 0.1 4.3e-14 52.9 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX38002.1 - 9.1e-28 93.2 1.1 8.2e-06 25.8 0.0 6.5 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 EKX38002.1 - 1e-26 92.1 9.8 0.00016 22.0 0.1 6.9 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EKX38002.1 - 1e-18 67.1 5.1 3.1e-07 30.5 0.0 5.0 2 2 3 5 5 5 4 Ankyrin repeats (many copies) TPMT PF05724.11 EKX38003.1 - 9.8e-31 107.1 0.0 1.2e-30 106.8 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.6 EKX38003.1 - 2.9e-10 40.1 0.0 4.4e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX38003.1 - 4.6e-10 40.1 0.0 7.2e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX38003.1 - 1.3e-09 38.5 0.0 2.5e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX38003.1 - 1.4e-09 38.0 0.0 1.9e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX38003.1 - 2e-09 38.1 0.0 4e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N2227 PF07942.12 EKX38003.1 - 0.14 11.3 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 N2227-like protein KBP_C PF12309.8 EKX38004.1 - 4.1e-13 49.6 2.3 5.1e-07 29.6 0.0 2.8 2 1 1 3 3 3 2 KIF-1 binding protein C terminal TPR_10 PF13374.6 EKX38004.1 - 3.3e-06 26.8 1.4 0.0058 16.5 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat POTRA_2 PF08479.11 EKX38004.1 - 0.068 13.0 0.0 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 POTRA domain, ShlB-type TPR_12 PF13424.6 EKX38004.1 - 0.074 13.4 6.2 3.5 8.0 0.9 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EKX38004.1 - 0.083 13.0 0.2 0.78 9.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.32 EKX38005.1 - 0.11 13.4 0.4 0.34 11.8 0.4 1.8 1 0 0 1 1 1 0 WD domain, G-beta repeat Archease PF01951.16 EKX38006.1 - 1.3e-44 151.8 0.3 1.4e-44 151.7 0.3 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) HTS PF04204.16 EKX38007.1 - 2.3e-85 286.2 0.0 2.7e-85 285.9 0.0 1.0 1 0 0 1 1 1 1 Homoserine O-succinyltransferase ParB PF08775.10 EKX38008.1 - 0.54 10.7 8.3 0.12 12.9 3.5 2.2 1 1 1 2 2 2 0 ParB family Peptidase_M14 PF00246.24 EKX38009.1 - 1.4e-08 34.9 0.0 3.7e-08 33.5 0.0 1.7 1 1 0 1 1 1 1 Zinc carboxypeptidase Spt46 PF17734.1 EKX38009.1 - 0.073 12.9 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 46 DUF4572 PF15139.6 EKX38010.1 - 1.2e-05 25.4 0.0 2.4e-05 24.3 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4572) GTP_EFTU PF00009.27 EKX38011.1 - 4.2e-51 173.2 0.0 6.4e-51 172.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EKX38011.1 - 9.6e-21 73.6 0.0 2e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EKX38011.1 - 5.9e-15 55.4 0.5 1.1e-14 54.6 0.5 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 LepA_C PF06421.12 EKX38011.1 - 6.7e-12 45.5 0.0 1.3e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus MMR_HSR1 PF01926.23 EKX38011.1 - 2.2e-06 27.7 0.0 7.9e-06 25.9 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 EKX38011.1 - 0.0008 19.0 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EKX38011.1 - 0.049 13.1 0.0 0.096 12.1 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 EKX38011.1 - 0.14 12.2 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DUF3446 PF11928.8 EKX38011.1 - 0.85 10.0 7.0 1.9 8.9 7.0 1.5 1 0 0 1 1 1 0 Early growth response N-terminal domain PKD_channel PF08016.12 EKX38012.1 - 2.9e-44 151.4 9.2 2.9e-44 151.4 9.2 1.9 1 1 1 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 EKX38012.1 - 2e-11 43.6 18.2 2e-11 43.6 18.2 2.1 2 1 0 2 2 2 1 Ion transport protein ELO PF01151.18 EKX38012.1 - 0.00091 18.8 3.4 0.0018 17.9 3.4 1.4 1 0 0 1 1 1 1 GNS1/SUR4 family Cmc1 PF08583.10 EKX38013.1 - 3.6e-13 49.3 6.0 6e-13 48.6 6.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 EKX38013.1 - 0.054 13.5 4.3 0.12 12.5 4.3 1.6 1 1 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 EKX38013.1 - 0.32 11.2 6.7 6.2 7.1 7.4 2.2 1 1 1 2 2 2 0 CHCH domain Ndufs5 PF10200.9 EKX38013.1 - 0.35 11.2 3.9 0.64 10.3 3.7 1.5 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF4692 PF15763.5 EKX38015.1 - 0.02 15.3 2.9 0.04 14.4 0.0 2.3 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) Flg_hook PF02120.16 EKX38016.1 - 0.12 12.3 0.1 0.18 11.7 0.1 1.2 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK Chlorophyllase2 PF12740.7 EKX38017.1 - 5e-11 42.0 0.0 1.1e-09 37.6 0.0 2.3 2 1 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EKX38017.1 - 1.4e-07 30.9 0.1 3.9e-07 29.4 0.0 1.7 2 1 0 2 2 2 1 Chlorophyllase Abhydrolase_6 PF12697.7 EKX38017.1 - 0.00057 20.6 0.9 0.0012 19.5 0.9 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EKX38017.1 - 0.00067 19.0 0.1 0.41 9.9 0.0 2.8 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EKX38017.1 - 0.041 13.5 0.0 0.12 11.9 0.0 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold Thioesterase PF00975.20 EKX38017.1 - 0.11 12.6 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Thioesterase domain zf-CW PF07496.15 EKX38018.1 - 1.7e-08 34.4 4.8 6.1e-08 32.6 4.8 2.1 1 0 0 1 1 1 1 CW-type Zinc Finger Agenet PF05641.12 EKX38018.1 - 1.9e-08 34.7 1.2 0.0074 16.7 0.0 3.2 3 0 0 3 3 3 2 Agenet domain TTD PF12148.8 EKX38018.1 - 0.029 14.2 0.3 0.2 11.5 0.3 2.4 1 1 0 1 1 1 0 Tandem tudor domain within UHRF1 DUF3039 PF11238.8 EKX38018.1 - 0.12 12.1 0.1 0.33 10.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) zf-CSL PF05207.13 EKX38018.1 - 0.19 11.5 2.1 19 5.1 0.1 3.1 3 0 0 3 3 3 0 CSL zinc finger DEAD PF00270.29 EKX38019.1 - 4.6e-32 111.2 0.0 1.9e-15 57.1 0.0 2.6 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX38019.1 - 1.7e-30 105.6 0.1 6.6e-30 103.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Ank_4 PF13637.6 EKX38020.1 - 1.5e-15 57.4 1.6 1.1e-10 41.8 1.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX38020.1 - 6.2e-12 45.9 0.8 1.3e-09 38.5 1.3 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX38020.1 - 2.4e-09 37.3 2.9 8.4e-07 29.2 1.5 3.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX38020.1 - 2.5e-08 33.5 1.7 0.00024 21.3 0.4 4.4 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 EKX38020.1 - 3e-08 33.7 4.1 1.1e-05 25.6 1.5 3.4 3 0 0 3 3 3 2 Ankyrin repeat HAGH_C PF16123.5 EKX38020.1 - 0.071 13.6 0.0 0.37 11.3 0.0 2.3 1 0 0 1 1 1 0 Hydroxyacylglutathione hydrolase C-terminus SH3_2 PF07653.17 EKX38021.1 - 0.0048 16.5 0.0 0.0091 15.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Med7 PF05983.11 EKX38022.1 - 1.8 8.6 12.5 0.32 11.1 7.8 2.2 2 1 0 2 2 2 0 MED7 protein IQ PF00612.27 EKX38023.1 - 0.0011 18.6 0.1 0.0039 16.8 0.1 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif ATG16 PF08614.11 EKX38024.1 - 0.0011 19.3 21.3 0.071 13.3 2.0 2.6 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Mu-transpos_C PF09299.11 EKX38024.1 - 0.1 12.6 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Mu transposase, C-terminal CENP-F_leu_zip PF10473.9 EKX38024.1 - 0.68 9.9 22.6 10 6.1 0.1 3.8 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.10 EKX38024.1 - 0.99 9.6 6.8 2.6 8.2 4.5 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family BRE1 PF08647.11 EKX38024.1 - 1.7 8.8 13.1 2.2 8.4 7.9 3.0 2 1 2 4 4 4 0 BRE1 E3 ubiquitin ligase GvpG PF05120.12 EKX38024.1 - 1.7 8.7 7.1 0.55 10.3 0.7 2.9 3 0 0 3 3 3 0 Gas vesicle protein G Spc24 PF08286.11 EKX38024.1 - 3.4 8.0 10.8 1.7 8.9 1.9 3.5 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Herpes_UL52 PF03121.15 EKX38025.1 - 4.7e-11 42.5 0.1 1.6e-10 40.8 0.1 1.8 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase Bromodomain PF00439.25 EKX38026.1 - 2.2e-21 75.7 0.9 1.9e-17 63.1 0.2 3.3 2 1 0 2 2 2 2 Bromodomain SAM_1 PF00536.30 EKX38026.1 - 1e-08 35.5 1.9 3.3e-05 24.2 0.1 2.9 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EKX38026.1 - 1e-05 25.6 0.3 0.00085 19.4 0.0 2.5 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) TUDOR_5 PF18359.1 EKX38026.1 - 0.005 16.5 0.2 0.011 15.5 0.2 1.6 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 Spc7 PF08317.11 EKX38028.1 - 0.005 15.8 8.9 0.005 15.8 8.9 1.8 2 0 0 2 2 2 1 Spc7 kinetochore protein DUF4472 PF14739.6 EKX38028.1 - 0.0056 17.4 4.3 0.0056 17.4 4.3 3.1 3 0 0 3 3 2 1 Domain of unknown function (DUF4472) YkyA PF10368.9 EKX38028.1 - 0.015 14.9 0.9 0.035 13.8 0.9 1.7 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF4201 PF13870.6 EKX38028.1 - 0.098 12.4 10.7 2 8.1 3.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) LigT_PEase PF02834.16 EKX38028.1 - 0.12 12.5 0.3 23 5.3 0.1 2.7 2 0 0 2 2 2 0 LigT like Phosphoesterase TAL_effector PF03377.13 EKX38028.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 TAL effector repeat SOAR PF16533.5 EKX38028.1 - 0.22 11.5 0.1 0.22 11.5 0.1 2.9 2 1 1 3 3 3 0 STIM1 Orai1-activating region TMF_TATA_bd PF12325.8 EKX38028.1 - 0.47 10.7 11.8 0.81 9.9 1.5 3.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding MscS_porin PF12795.7 EKX38028.1 - 0.55 9.7 8.3 0.094 12.2 3.4 2.2 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain Fez1 PF06818.15 EKX38028.1 - 0.95 9.9 16.9 1.6 9.2 15.0 2.3 1 1 1 2 2 2 0 Fez1 PI3K_P85_iSH2 PF16454.5 EKX38028.1 - 1.1 8.9 9.0 0.59 9.7 3.2 2.6 1 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4200 PF13863.6 EKX38028.1 - 1.8 9.0 9.7 7.5 7.0 4.8 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.9 EKX38028.1 - 5.9 6.9 17.1 3.2 7.8 1.1 3.1 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Peptidase_M14 PF00246.24 EKX38029.1 - 7.5e-18 65.3 0.0 3.2e-17 63.3 0.0 2.1 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 EKX38029.1 - 5e-10 39.7 0.4 1.8e-09 37.9 0.1 2.1 2 0 0 2 2 2 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 EKX38029.1 - 0.0079 15.3 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF769 PF05590.11 EKX38029.1 - 0.14 11.6 0.1 0.3 10.5 0.1 1.5 1 0 0 1 1 1 0 Xylella fastidiosa protein of unknown function (DUF769) Collagen PF01391.18 EKX38031.1 - 1.3e-05 24.9 14.1 1.3e-05 24.9 14.1 2.3 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) Tweety PF04906.13 EKX38031.1 - 0.0057 15.4 0.0 0.18 10.4 0.0 2.1 2 0 0 2 2 2 1 Tweety HR1 PF02185.16 EKX38031.1 - 0.079 13.1 3.1 0.077 13.1 1.6 1.8 2 0 0 2 2 2 0 Hr1 repeat Complex1_49kDa PF00346.19 EKX38031.1 - 0.1 11.7 0.6 2.8 7.0 0.2 2.2 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit KxDL PF10241.9 EKX38031.1 - 0.11 12.8 1.9 0.25 11.6 1.9 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein BLOC1_2 PF10046.9 EKX38031.1 - 0.25 11.7 0.6 1.6 9.1 0.3 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF883 PF05957.13 EKX38031.1 - 3.8 8.2 6.0 2.5 8.7 1.9 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Patatin PF01734.22 EKX38032.1 - 6.3e-21 75.5 0.0 4.3e-20 72.8 0.0 2.4 2 1 0 2 2 2 1 Patatin-like phospholipase LRR_8 PF13855.6 EKX38032.1 - 3.9e-09 36.1 7.1 3.9e-09 36.1 7.1 3.5 4 0 0 4 4 4 1 Leucine rich repeat LRR_4 PF12799.7 EKX38032.1 - 0.00051 20.4 24.8 0.0015 18.9 3.5 4.6 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) AlaE PF06610.13 EKX38032.1 - 0.15 12.1 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 L-alanine exporter LRR_9 PF14580.6 EKX38032.1 - 0.3 10.6 3.8 0.97 8.9 3.6 1.9 1 1 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 EKX38032.1 - 0.85 9.8 2.8 61 4.0 0.1 4.0 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 EKX38032.1 - 2.5 9.0 16.8 4.8 8.1 0.2 5.8 6 0 0 6 6 6 0 Leucine Rich Repeat BPL_LplA_LipB PF03099.19 EKX38033.1 - 2.1e-14 53.5 0.0 5.2e-14 52.3 0.0 1.7 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 EKX38033.1 - 3.8e-05 23.5 0.1 7.4e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain SUN PF03856.13 EKX38033.1 - 0.076 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Beta-glucosidase (SUN family) HlyD_3 PF13437.6 EKX38033.1 - 0.16 12.7 0.0 0.29 11.8 0.0 1.3 1 0 0 1 1 1 0 HlyD family secretion protein His_Phos_1 PF00300.22 EKX38035.1 - 5.2e-40 137.2 0.0 5.9e-40 137.0 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RWP-RK PF02042.15 EKX38036.1 - 5.7e-14 51.8 0.8 1.3e-13 50.7 0.2 1.7 1 1 1 2 2 2 1 RWP-RK domain Cytomega_gL PF01801.16 EKX38036.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein L LRR_8 PF13855.6 EKX38037.1 - 2.3e-75 248.3 67.2 9.2e-16 57.4 7.1 8.0 1 1 7 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 EKX38037.1 - 2.8e-42 142.0 46.7 1.5e-09 38.0 3.4 8.1 4 2 4 9 9 9 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX38037.1 - 2.2e-32 111.7 0.0 1.8e-10 40.8 0.0 3.3 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EKX38037.1 - 5.9e-19 65.7 40.2 0.028 14.9 0.1 12.4 13 1 0 13 13 13 6 Leucine Rich Repeat LRR_9 PF14580.6 EKX38037.1 - 7.1e-13 48.4 12.7 0.003 17.1 0.4 5.0 1 1 4 5 5 5 5 Leucine-rich repeat LRR_6 PF13516.6 EKX38037.1 - 0.11 12.6 0.2 0.11 12.6 0.2 10.2 13 0 0 13 13 13 0 Leucine Rich repeat YcgL PF05166.13 EKX38037.1 - 0.11 12.9 1.0 2.8 8.4 0.0 3.4 2 1 2 4 4 4 0 YcgL domain Ank_5 PF13857.6 EKX38038.1 - 8.6e-09 35.5 1.5 2.4e-05 24.5 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX38038.1 - 9.9e-09 35.7 0.0 0.00012 22.6 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX38038.1 - 1.1e-07 32.2 0.3 2.6e-05 24.7 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX38038.1 - 9e-07 28.7 0.3 0.00013 22.1 0.0 3.9 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 EKX38038.1 - 6e-05 23.3 0.4 0.0074 16.7 0.2 3.3 2 1 0 2 2 2 1 Ankyrin repeat RRM_1 PF00076.22 EKX38039.1 - 2e-10 40.3 0.0 8e-10 38.4 0.0 2.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HhH-GPD PF00730.25 EKX38039.1 - 0.035 14.6 0.0 0.21 12.0 0.0 2.4 2 0 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein UCH PF00443.29 EKX38040.1 - 5.3e-44 150.6 0.0 9.2e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EKX38040.1 - 6.3e-14 52.3 0.0 1.2e-13 51.3 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EKX38040.1 - 0.0041 16.6 0.4 0.39 10.2 0.2 3.0 2 1 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Kelch_2 PF07646.15 EKX38042.1 - 1.6e-06 27.9 2.1 0.029 14.4 0.0 3.2 3 0 0 3 3 3 3 Kelch motif Kelch_5 PF13854.6 EKX38042.1 - 6.7e-06 26.0 0.1 0.0084 16.1 0.0 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.6 EKX38042.1 - 6.7e-06 26.2 0.1 0.0012 19.1 0.0 2.4 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.6 EKX38042.1 - 7.8e-06 26.0 1.9 1.2 9.5 0.1 3.3 2 1 1 3 3 3 3 Kelch motif Kelch_4 PF13418.6 EKX38042.1 - 8.1e-06 25.7 6.7 0.097 12.7 1.2 3.9 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.25 EKX38042.1 - 0.0024 17.4 2.4 0.3 10.7 0.1 3.1 3 0 0 3 3 3 1 Kelch motif IP_trans PF02121.18 EKX38043.1 - 4.4e-32 111.6 0.0 6.4e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Plug_translocon PF10559.9 EKX38043.1 - 0.18 11.7 0.0 0.53 10.2 0.0 1.8 1 0 0 1 1 1 0 Plug domain of Sec61p Ank_4 PF13637.6 EKX38044.1 - 1.4e-18 67.0 0.2 1.5e-08 35.0 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX38044.1 - 6.3e-18 65.2 0.2 6.5e-14 52.3 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EKX38044.1 - 1.5e-13 50.5 0.0 0.00062 20.1 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EKX38044.1 - 3.2e-10 39.4 0.1 0.047 14.3 0.0 4.2 3 1 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EKX38044.1 - 5e-09 36.2 0.1 0.00049 20.3 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) DUF460 PF04312.13 EKX38046.1 - 0.0068 16.1 2.3 0.68 9.6 0.7 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF460) GBP_C PF02841.14 EKX38046.1 - 0.37 10.2 19.1 0.63 9.4 19.1 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain LMBR1 PF04791.16 EKX38046.1 - 2.1 7.2 3.8 2.3 7.0 3.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein AAA PF00004.29 EKX38047.1 - 4.1e-40 137.3 0.0 8.3e-40 136.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EKX38047.1 - 1.3e-10 40.9 0.1 3e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EKX38047.1 - 8.4e-05 22.9 0.0 0.0038 17.5 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 EKX38047.1 - 0.00017 21.7 0.0 0.00079 19.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EKX38047.1 - 0.00042 20.7 0.1 0.0086 16.5 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EKX38047.1 - 0.0006 19.8 0.1 0.0033 17.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EKX38047.1 - 0.0063 17.1 0.0 0.035 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 EKX38047.1 - 0.0068 15.6 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EKX38047.1 - 0.011 15.5 0.0 0.04 13.7 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EKX38047.1 - 0.014 15.6 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EKX38047.1 - 0.022 14.5 0.2 0.097 12.4 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EKX38047.1 - 0.031 14.4 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EKX38047.1 - 0.044 14.2 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 EKX38047.1 - 0.073 12.4 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 EKX38047.1 - 0.084 12.2 0.2 3.9 6.8 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 EKX38047.1 - 0.14 11.6 0.0 0.34 10.4 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 EKX38047.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF218 PF02698.17 EKX38048.1 - 1e-21 77.3 0.0 1.2e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain DnaJ_C PF01556.18 EKX38049.1 - 6.1e-39 133.5 0.1 1.4e-38 132.3 0.1 1.6 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EKX38049.1 - 9.3e-25 86.5 0.6 1.8e-24 85.7 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EKX38049.1 - 7.6e-12 45.4 19.3 1.4e-11 44.6 19.3 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EKX38049.1 - 0.055 13.4 17.4 0.26 11.3 5.8 2.5 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DZR PF12773.7 EKX38049.1 - 0.17 11.9 7.0 0.58 10.2 7.1 1.8 1 1 0 1 1 1 0 Double zinc ribbon TackOD1 PF18551.1 EKX38049.1 - 5.1 6.7 5.4 2 8.1 0.8 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 cwf21 PF08312.12 EKX38050.1 - 0.053 13.7 10.0 0.14 12.3 3.1 2.8 2 0 0 2 2 2 0 cwf21 domain Med9 PF07544.13 EKX38050.1 - 0.07 13.2 4.8 3 8.0 0.3 2.6 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 V_ATPase_I PF01496.19 EKX38050.1 - 0.097 10.6 5.3 0.13 10.2 5.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Vicilin_N PF04702.12 EKX38050.1 - 1.1 9.1 8.5 1.8 8.4 8.6 1.5 1 1 0 1 1 1 0 Vicilin N terminal region DUF2205 PF10224.9 EKX38050.1 - 1.4 8.9 8.7 15 5.7 1.2 3.0 1 1 2 3 3 3 0 Short coiled-coil protein Fmp27_WPPW PF10359.9 EKX38050.1 - 2 7.1 7.7 2.7 6.7 7.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Nbl1_Borealin_N PF10444.9 EKX38050.1 - 4.8 6.9 9.7 3.5 7.3 3.0 2.8 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal DUF2203 PF09969.9 EKX38051.1 - 0.057 14.1 4.7 0.059 14.1 3.2 1.9 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF775 PF05603.12 EKX38051.1 - 0.26 10.8 0.0 0.37 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF4407 PF14362.6 EKX38051.1 - 0.36 10.1 7.4 0.55 9.5 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ank_4 PF13637.6 EKX38052.1 - 8.6e-28 96.4 0.1 2.3e-13 50.3 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX38052.1 - 3.2e-20 71.9 0.4 2.8e-08 33.9 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX38052.1 - 4.1e-19 68.9 0.0 2e-18 66.8 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX38052.1 - 8e-19 67.2 0.2 4.1e-08 33.3 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EKX38052.1 - 2.4e-18 64.3 0.0 3.5e-06 26.9 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat LolA_like PF17131.4 EKX38053.1 - 0.067 12.9 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein-sorting protein P34-Arc PF04045.14 EKX38055.1 - 2.1e-62 211.0 0.8 2.7e-62 210.6 0.8 1.2 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Acyltransferase PF01553.21 EKX38056.1 - 3e-10 39.8 0.0 4.1e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Sec20 PF03908.13 EKX38059.1 - 7.5e-07 29.0 2.8 7.5e-07 29.0 2.8 2.9 3 0 0 3 3 3 1 Sec20 V-SNARE_C PF12352.8 EKX38059.1 - 1e-06 28.9 4.2 1e-06 28.9 4.2 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DUF4407 PF14362.6 EKX38059.1 - 0.0035 16.7 7.6 0.032 13.6 7.6 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) SNARE PF05739.19 EKX38059.1 - 0.01 15.8 3.4 0.01 15.8 3.4 2.1 3 0 0 3 3 3 0 SNARE domain Mobilization_B PF17511.2 EKX38059.1 - 0.036 14.4 0.6 0.13 12.6 0.5 1.9 1 1 0 1 1 1 0 Mobilization protein B DUF1676 PF07898.13 EKX38059.1 - 0.11 12.6 2.4 0.17 11.9 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Prominin PF05478.11 EKX38059.1 - 0.12 10.3 7.7 0.019 12.9 2.8 1.8 1 1 0 2 2 2 0 Prominin TMPIT PF07851.13 EKX38059.1 - 0.13 11.5 5.1 1.1 8.4 0.1 2.4 2 1 0 2 2 2 0 TMPIT-like protein DUF5089 PF17002.5 EKX38059.1 - 0.14 12.0 11.5 0.033 14.1 6.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5089) ING PF12998.7 EKX38059.1 - 0.14 12.7 8.5 0.22 12.2 0.3 3.5 2 1 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Calcyon PF06387.11 EKX38059.1 - 0.15 12.0 1.5 0.29 11.1 1.5 1.5 1 1 0 1 1 1 0 D1 dopamine receptor-interacting protein (calcyon) DUF1664 PF07889.12 EKX38059.1 - 0.18 11.9 8.8 1.6 8.7 4.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Tropomyosin PF00261.20 EKX38059.1 - 1.1 8.6 21.5 4.4 6.6 0.9 3.1 2 1 0 3 3 3 0 Tropomyosin Arm-DNA-bind_5 PF17293.2 EKX38059.1 - 1.2 9.6 5.5 1.8 9.0 0.0 2.9 3 0 0 3 3 3 0 Arm DNA-binding domain Spc7 PF08317.11 EKX38059.1 - 1.3 7.8 18.0 1.4 7.7 6.0 2.6 2 1 0 2 2 2 0 Spc7 kinetochore protein V-SNARE PF05008.15 EKX38059.1 - 3.2 8.2 11.1 21 5.6 0.1 4.4 5 1 0 5 5 4 0 Vesicle transport v-SNARE protein N-terminus Seryl_tRNA_N PF02403.22 EKX38059.1 - 7.9 6.8 17.4 0.61 10.3 2.8 3.8 2 2 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF1768 PF08719.11 EKX38061.1 - 2e-10 41.1 0.1 2.6e-10 40.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) NAD_binding_10 PF13460.6 EKX38062.1 - 2e-28 99.5 0.0 2.7e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EKX38062.1 - 1.7e-08 33.9 0.1 2.3e-08 33.4 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 EKX38062.1 - 2.5e-06 27.3 0.1 4.4e-06 26.4 0.0 1.4 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 EKX38062.1 - 2.6e-05 23.8 0.0 4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EKX38062.1 - 0.0044 17.5 0.2 0.0099 16.3 0.1 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EKX38062.1 - 0.0079 15.4 0.0 0.026 13.6 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EKX38062.1 - 0.026 14.0 0.1 0.061 12.8 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase KR PF08659.10 EKX38062.1 - 0.052 13.5 0.2 2.6 7.9 0.1 2.4 1 1 0 2 2 2 0 KR domain LysM PF01476.20 EKX38063.1 - 7.5e-13 48.3 0.3 3e-06 27.2 0.0 3.4 3 0 0 3 3 3 3 LysM domain ADP_ribosyl_GH PF03747.14 EKX38065.1 - 2e-38 132.8 1.0 2.5e-38 132.5 1.0 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase LON_substr_bdg PF02190.16 EKX38066.1 - 7.7e-09 35.7 0.0 9.8e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain PKD_channel PF08016.12 EKX38067.1 - 7.6e-74 248.9 4.0 7.6e-74 248.9 4.0 1.3 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 EKX38067.1 - 2.4e-15 56.4 17.4 2.4e-15 56.4 17.4 1.8 2 0 0 2 2 2 1 Ion transport protein TPR_2 PF07719.17 EKX38068.1 - 2.8e-17 61.4 0.7 0.00019 21.3 0.0 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 EKX38068.1 - 2.7e-16 58.6 0.5 0.00026 20.7 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat VHP PF02209.19 EKX38068.1 - 3.8e-16 58.9 1.9 6.9e-16 58.0 1.9 1.5 1 0 0 1 1 1 1 Villin headpiece domain TPR_8 PF13181.6 EKX38068.1 - 7.9e-10 38.2 0.4 0.037 14.2 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX38068.1 - 1.2e-08 34.4 0.9 0.0019 17.8 0.0 4.3 4 0 0 4 4 4 2 TPR repeat TPR_16 PF13432.6 EKX38068.1 - 3.5e-07 30.8 0.3 0.0034 18.0 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX38068.1 - 5.8e-07 29.7 0.8 1.8 8.9 0.0 3.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 EKX38068.1 - 1e-06 28.8 0.2 0.041 14.0 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX38068.1 - 5.2e-06 26.5 0.8 0.55 10.7 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX38068.1 - 0.00015 22.3 1.6 0.47 11.4 0.0 3.9 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX38068.1 - 0.00016 22.1 0.2 0.96 10.2 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX38068.1 - 0.00026 20.8 0.0 0.52 10.5 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat DUF3856 PF12968.7 EKX38068.1 - 0.0013 18.8 0.4 0.017 15.2 0.3 2.4 1 1 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 EKX38068.1 - 0.0042 16.9 3.6 13 5.8 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Golgin_A5 PF09787.9 EKX38068.1 - 0.013 15.0 0.5 0.019 14.4 0.5 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 TPR_19 PF14559.6 EKX38068.1 - 0.013 16.0 1.6 12 6.5 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Sec8_exocyst PF04048.14 EKX38068.1 - 0.076 12.9 0.3 4.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Sec16_C PF12931.7 EKX38068.1 - 0.088 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 SWIB PF02201.18 EKX38068.1 - 0.16 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 SWIB/MDM2 domain DUF5525 PF17663.1 EKX38068.1 - 0.72 7.9 22.3 1 7.3 22.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5525) zf-CCCH_4 PF18044.1 EKX38069.1 - 4.3e-13 48.7 24.4 2.5e-05 24.0 3.9 3.6 3 0 0 3 3 3 3 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EKX38069.1 - 1.3e-12 47.3 23.7 5.3e-06 26.3 1.8 3.7 3 1 0 3 3 3 3 Zinc finger domain zf-RING_2 PF13639.6 EKX38069.1 - 6e-09 36.1 11.0 1.7e-08 34.7 5.6 2.9 2 0 0 2 2 2 1 Ring finger domain Torus PF16131.5 EKX38069.1 - 2.2e-08 34.8 11.9 0.012 16.3 0.5 3.3 2 1 1 3 3 3 3 Torus domain zf-C3HC4 PF00097.25 EKX38069.1 - 4.6e-08 32.8 5.5 2e-07 30.8 4.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.24 EKX38069.1 - 5e-08 32.7 21.8 0.00043 20.1 1.2 3.6 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.6 EKX38069.1 - 2.1e-05 24.4 9.3 3e-05 23.9 7.8 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-CCCH_2 PF14608.6 EKX38069.1 - 8.7e-05 22.8 26.2 0.0031 17.9 1.5 3.8 3 1 0 3 3 3 2 RNA-binding, Nab2-type zinc finger zf-RING_UBOX PF13445.6 EKX38069.1 - 0.00032 20.7 4.9 0.001 19.1 4.9 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 EKX38069.1 - 0.00039 20.1 6.0 0.0022 17.7 4.2 2.7 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EKX38069.1 - 0.0004 20.2 7.8 0.0004 20.2 7.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX38069.1 - 0.00052 20.2 6.2 0.0051 17.1 6.2 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-CCCH_3 PF15663.5 EKX38069.1 - 0.0013 18.9 1.5 0.0013 18.9 1.5 2.1 2 1 0 2 2 2 1 Zinc-finger containing family Prok-RING_4 PF14447.6 EKX38069.1 - 0.0035 17.2 6.9 0.0035 17.2 6.9 2.8 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EKX38069.1 - 0.004 17.3 2.5 0.004 17.3 2.5 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EKX38069.1 - 0.022 14.6 9.1 0.085 12.7 7.7 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EKX38069.1 - 3.7 7.7 12.0 0.09 12.8 4.2 2.4 2 2 1 3 3 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger TGF_beta_GS PF08515.12 EKX38071.1 - 7.1e-10 38.2 33.8 7.8 6.1 0.1 10.3 10 0 0 10 10 10 9 Transforming growth factor beta type I GS-motif VRR_NUC PF08774.11 EKX38071.1 - 0.049 13.7 0.4 11 6.1 0.0 3.4 1 1 1 2 2 2 0 VRR-NUC domain MFS_1 PF07690.16 EKX38072.1 - 4.6e-27 94.9 32.7 4.6e-27 94.9 32.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Wzy_C PF04932.15 EKX38072.1 - 0.019 14.6 0.4 0.019 14.6 0.4 3.3 3 1 0 3 3 3 0 O-Antigen ligase Phage_holin_3_6 PF07332.11 EKX38072.1 - 0.026 14.5 1.7 0.026 14.5 1.7 3.9 3 1 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Vpu PF00558.19 EKX38072.1 - 0.22 11.3 0.4 0.8 9.5 0.1 2.1 2 0 0 2 2 2 0 Vpu protein Phage_Gp23 PF10669.9 EKX38072.1 - 0.44 10.9 1.6 5.2 7.4 0.1 2.3 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) MFS_3 PF05977.13 EKX38072.1 - 0.6 8.4 13.5 0.099 11.0 5.2 2.6 1 1 0 2 2 2 0 Transmembrane secretion effector Halogen_Hydrol PF10112.9 EKX38072.1 - 6.4 6.7 7.5 1.2 9.1 0.3 2.9 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DGF-1_C PF11040.8 EKX38073.1 - 0.033 14.2 0.0 0.16 12.0 0.0 2.2 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Raffinose_syn PF05691.12 EKX38074.1 - 1.1e-180 602.1 0.0 6.3e-180 599.6 0.0 1.9 1 1 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 zf-CCHC PF00098.23 EKX38075.1 - 0.13 12.4 1.4 0.26 11.5 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 EKX38075.1 - 0.17 11.6 1.2 0.32 10.7 1.2 1.5 1 0 0 1 1 1 0 Zinc knuckle PDZ_2 PF13180.6 EKX38076.1 - 2e-09 37.6 0.0 6.9e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 PDZ domain WD40 PF00400.32 EKX38076.1 - 6.9e-07 29.9 5.7 0.15 13.0 0.1 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat PDZ PF00595.24 EKX38076.1 - 9.7e-07 29.1 0.2 3.4e-06 27.3 0.1 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EKX38076.1 - 2.6e-06 27.2 0.2 0.00012 21.8 0.0 2.9 2 0 0 2 2 2 1 PDZ domain PQQ_3 PF13570.6 EKX38076.1 - 0.0099 16.3 2.5 1 9.9 0.0 4.0 4 1 0 4 4 4 1 PQQ-like domain Tricorn_PDZ PF14685.6 EKX38076.1 - 0.065 13.2 0.1 1.1 9.3 0.0 2.7 3 0 0 3 3 3 0 Tricorn protease PDZ domain DUF725 PF05267.12 EKX38077.1 - 0.0019 18.1 2.6 0.0019 18.1 2.6 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF725) HrpF PF06266.12 EKX38077.1 - 0.064 13.6 2.0 0.091 13.1 0.1 2.1 2 0 0 2 2 2 0 HrpF protein DUF4962 PF16332.5 EKX38077.1 - 0.25 9.8 3.1 0.29 9.6 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) RWP-RK PF02042.15 EKX38080.1 - 1.4e-11 44.2 0.1 2.5e-11 43.4 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX38080.1 - 0.22 11.4 0.0 0.59 10.0 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family EF-hand_7 PF13499.6 EKX38081.1 - 6e-05 23.4 0.0 0.00015 22.1 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX38081.1 - 0.11 12.1 0.0 0.11 12.1 0.0 2.3 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.6 EKX38081.1 - 0.17 11.9 0.4 1.5 9.0 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain Cons_hypoth95 PF03602.15 EKX38084.1 - 0.015 15.0 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 UPF0020 PF01170.18 EKX38084.1 - 0.033 13.9 0.0 14 5.3 0.0 3.0 2 1 0 2 2 2 0 Putative RNA methylase family UPF0020 PrmA PF06325.13 EKX38084.1 - 0.045 13.1 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) LRR_4 PF12799.7 EKX38085.1 - 3.7e-28 97.1 28.7 7.5e-09 35.7 2.2 5.3 2 1 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX38085.1 - 2.1e-19 69.0 28.0 2.6e-06 27.1 2.4 4.5 1 1 3 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 EKX38085.1 - 8.8e-15 54.6 16.2 6.8e-08 32.2 2.2 3.2 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 EKX38085.1 - 0.0001 22.3 20.3 3.9 8.4 0.3 8.7 8 1 0 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.6 EKX38085.1 - 0.00014 21.6 25.4 0.25 11.5 0.2 8.2 7 2 1 8 8 8 3 Leucine Rich repeat LRR_2 PF07723.13 EKX38085.1 - 0.1 13.3 5.0 17 6.2 0.0 4.5 3 2 2 5 5 5 0 Leucine Rich Repeat Sel1 PF08238.12 EKX38086.1 - 6.6e-48 160.1 31.4 3e-08 34.1 0.8 7.2 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.6 EKX38086.1 - 0.00017 22.0 10.2 5.8 7.8 0.0 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX38086.1 - 0.14 12.0 9.6 1.6 8.6 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 EKX38086.1 - 4.5 7.0 7.8 2 8.1 0.2 3.8 3 1 0 3 3 3 0 TPR repeat FSH1 PF03959.13 EKX38087.1 - 9.2e-21 74.5 0.0 9.4e-16 58.1 0.0 2.1 1 1 1 2 2 2 2 Serine hydrolase (FSH1) DUF632 PF04782.12 EKX38089.1 - 0.0015 17.9 7.3 0.0023 17.3 7.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF632) PRT_C PF08372.10 EKX38089.1 - 0.19 11.5 2.2 3.8 7.3 0.1 2.4 1 1 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal FlaC_arch PF05377.11 EKX38089.1 - 3.9 7.9 7.1 17 5.9 0.0 3.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF2203 PF09969.9 EKX38089.1 - 8.6 7.1 8.2 1.3 9.8 0.7 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DPPIV_N PF00930.21 EKX38090.1 - 9.1e-83 277.9 0.0 1.8e-79 267.1 0.1 2.2 2 0 0 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EKX38090.1 - 3.7e-55 186.7 0.2 6e-55 186.0 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EKX38090.1 - 2.2e-12 47.2 1.8 3.5e-09 36.7 0.9 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 EKX38090.1 - 8e-06 25.6 0.0 2e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 EKX38090.1 - 3.3e-05 23.3 0.9 0.0015 17.9 0.2 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EKX38090.1 - 0.0016 19.1 0.2 0.0047 17.6 0.2 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.14 EKX38090.1 - 0.014 14.7 0.1 0.024 14.0 0.1 1.3 1 0 0 1 1 1 0 Secretory lipase DUF3141 PF11339.8 EKX38090.1 - 0.02 13.4 0.0 0.028 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) Abhydrolase_1 PF00561.20 EKX38090.1 - 0.021 14.5 0.6 0.052 13.2 0.2 1.8 1 1 0 2 2 2 0 alpha/beta hydrolase fold DUF5397 PF17375.2 EKX38090.1 - 0.083 12.6 0.2 0.18 11.6 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5397) BAAT_C PF08840.11 EKX38090.1 - 0.083 12.8 0.0 1.6 8.6 0.0 2.2 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 EKX38090.1 - 0.13 12.0 0.2 3.5 7.4 0.1 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF3337 PF11816.8 EKX38091.1 - 0.00045 20.1 0.2 0.066 13.1 0.0 2.7 1 1 2 3 3 3 1 Domain of unknown function (DUF3337) Nucleo_P87 PF07267.11 EKX38091.1 - 0.28 10.0 3.5 0.31 9.9 3.5 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Spt20 PF12090.8 EKX38091.1 - 0.28 10.7 6.8 0.36 10.4 6.8 1.2 1 0 0 1 1 1 0 Spt20 family Spore_coat_CotO PF14153.6 EKX38091.1 - 0.38 10.7 5.8 0.53 10.2 5.8 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Apt1 PF10351.9 EKX38091.1 - 0.93 8.3 10.8 1.1 8.0 10.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ndc1_Nup PF09531.10 EKX38091.1 - 1.3 7.6 8.4 1.3 7.6 8.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 EKX38091.1 - 1.6 7.4 8.5 2 7.1 8.5 1.1 1 0 0 1 1 1 0 Presenilin Dicty_REP PF05086.12 EKX38091.1 - 2.4 6.0 6.3 2.7 5.8 6.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SRP-alpha_N PF04086.13 EKX38091.1 - 2.8 7.8 16.2 3.5 7.5 16.2 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Macoilin PF09726.9 EKX38091.1 - 3.2 6.2 9.4 3.4 6.1 9.4 1.1 1 0 0 1 1 1 0 Macoilin family RR_TM4-6 PF06459.12 EKX38091.1 - 4.6 7.0 9.4 5.9 6.6 9.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 EKX38091.1 - 8.7 5.0 11.9 12 4.6 11.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Cytochrom_B561 PF03188.16 EKX38092.1 - 1.3e-16 61.0 0.9 2e-16 60.4 0.9 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 ENOD93 PF03386.14 EKX38092.1 - 0.038 13.9 2.9 0.069 13.0 0.2 2.5 2 0 0 2 2 2 0 Early nodulin 93 ENOD93 protein Peptidase_M14 PF00246.24 EKX38094.1 - 1.6e-20 74.1 0.0 8.4e-20 71.7 0.0 1.9 2 0 0 2 2 2 1 Zinc carboxypeptidase AstE_AspA PF04952.14 EKX38094.1 - 0.021 13.9 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Proteasome PF00227.26 EKX38095.1 - 6e-48 162.9 0.1 9.2e-48 162.2 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit GDC-P PF02347.16 EKX38096.1 - 3e-184 612.8 0.3 6.4e-172 572.2 0.1 3.0 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 EKX38096.1 - 8.3e-07 28.3 0.1 1.9e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EKX38096.1 - 0.0048 16.2 0.6 0.014 14.7 0.2 1.9 2 0 0 2 2 2 1 Beta-eliminating lyase THP2 PF09432.10 EKX38096.1 - 0.15 12.1 0.0 0.39 10.8 0.0 1.7 1 0 0 1 1 1 0 Tho complex subunit THP2 NAD_binding_10 PF13460.6 EKX38097.1 - 5e-29 101.5 0.0 5.6e-29 101.3 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EKX38097.1 - 1.2e-11 44.7 0.0 1.5e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EKX38097.1 - 5.7e-11 42.3 0.0 7.4e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 EKX38097.1 - 1.2e-05 25.5 0.0 1.8e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 EKX38097.1 - 2.3e-05 24.9 0.0 4e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 EKX38097.1 - 0.00018 21.6 0.2 0.00041 20.5 0.1 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_7 PF13241.6 EKX38097.1 - 0.00026 21.4 0.1 0.00033 21.1 0.1 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 EKX38097.1 - 0.0004 20.6 0.0 0.00059 20.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EKX38097.1 - 0.00078 19.5 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.19 EKX38097.1 - 0.00079 18.5 0.1 0.001 18.1 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EKX38097.1 - 0.0032 16.9 0.0 0.005 16.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.18 EKX38097.1 - 0.015 15.2 0.1 0.017 15.0 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EKX38097.1 - 0.02 14.3 0.0 0.04 13.3 0.0 1.5 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase HMG_box_5 PF14887.6 EKX38097.1 - 0.029 14.3 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box 5 2-Hacid_dh_C PF02826.19 EKX38097.1 - 0.032 13.6 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 EKX38097.1 - 0.033 13.3 0.0 0.037 13.1 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_10 PF13460.6 EKX38098.1 - 4.8e-33 114.6 0.0 5.5e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EKX38098.1 - 2.2e-11 43.8 0.0 3.2e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EKX38098.1 - 1.1e-10 41.4 0.0 1.9e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 EKX38098.1 - 2.3e-05 24.6 0.0 3.6e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.17 EKX38098.1 - 3.9e-05 24.1 0.0 7.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 EKX38098.1 - 0.00031 20.9 0.1 0.00073 19.7 0.1 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_7 PF13241.6 EKX38098.1 - 0.00047 20.6 0.1 0.0007 20.0 0.1 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding 3Beta_HSD PF01073.19 EKX38098.1 - 0.0014 17.7 0.1 0.0022 17.0 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 EKX38098.1 - 0.0015 18.6 0.0 0.0022 18.0 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 EKX38098.1 - 0.005 16.3 0.0 0.0087 15.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.18 EKX38098.1 - 0.023 14.6 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EKX38098.1 - 0.035 13.5 0.0 0.068 12.6 0.0 1.5 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase HMG_box_5 PF14887.6 EKX38098.1 - 0.043 13.8 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box 5 2-Hacid_dh_C PF02826.19 EKX38098.1 - 0.051 12.9 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 EKX38098.1 - 0.054 12.6 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Pkinase PF00069.25 EKX38099.1 - 7.5e-50 169.7 0.0 9.2e-50 169.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX38099.1 - 3.2e-49 167.5 0.0 3.6e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX38099.1 - 3.3e-05 23.9 0.9 0.0022 18.0 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX38099.1 - 0.00028 19.8 0.0 0.00051 18.9 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase LOR PF04525.12 EKX38100.1 - 8.1e-07 28.8 0.1 2.2e-05 24.2 0.1 2.0 1 1 0 1 1 1 1 LURP-one-related IncD PF17628.2 EKX38100.1 - 0.029 14.2 0.1 0.046 13.5 0.1 1.2 1 0 0 1 1 1 0 Inclusion membrane protein D Neurokinin_B PF03823.14 EKX38101.1 - 0.018 15.1 16.6 2.5 8.2 0.4 5.3 2 1 4 6 6 6 0 Neurokinin B Carn_acyltransf PF00755.20 EKX38102.1 - 3.5e-121 405.7 0.0 4e-107 359.3 0.0 2.0 1 1 1 2 2 2 2 Choline/Carnitine o-acyltransferase SurA_N_2 PF13623.6 EKX38102.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 SurA N-terminal domain ABC1 PF03109.16 EKX38103.1 - 8e-24 84.1 1.1 1.3e-22 80.2 0.3 2.9 3 1 0 3 3 3 1 ABC1 family APH PF01636.23 EKX38103.1 - 0.00065 19.7 0.1 0.045 13.7 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.25 EKX38103.1 - 0.029 13.7 0.2 0.16 11.3 0.2 2.1 1 1 0 1 1 1 0 Protein kinase domain WaaY PF06176.11 EKX38103.1 - 0.06 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Kinocilin PF15033.6 EKX38103.1 - 0.21 11.2 0.3 13 5.4 0.0 2.4 2 0 0 2 2 2 0 Kinocilin protein UBA PF00627.31 EKX38104.1 - 1e-05 25.3 0.7 6.4e-05 22.8 0.0 2.8 3 0 0 3 3 3 1 UBA/TS-N domain ubiquitin PF00240.23 EKX38104.1 - 4.4e-05 23.2 0.0 0.0001 22.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family RRM_1 PF00076.22 EKX38105.1 - 3.6e-17 62.0 0.0 3.9e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ala_racemase_N PF01168.20 EKX38105.1 - 0.11 12.1 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain RRM_7 PF16367.5 EKX38105.1 - 0.14 12.3 0.0 0.15 12.2 0.0 1.3 1 1 0 1 1 1 0 RNA recognition motif PDEase_I PF00233.19 EKX38106.1 - 1.9e-65 221.0 0.0 2.3e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 EKX38106.1 - 0.0034 17.6 0.4 0.0056 16.9 0.4 1.6 1 0 0 1 1 1 1 HD domain RWP-RK PF02042.15 EKX38107.1 - 6.1e-15 54.9 0.1 1.3e-14 53.9 0.1 1.5 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX38107.1 - 0.02 14.7 0.2 0.23 11.3 0.0 2.2 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family Sigma70_r4_2 PF08281.12 EKX38107.1 - 0.047 13.4 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 DAO PF01266.24 EKX38108.1 - 2.2e-14 53.8 0.0 8.9e-10 38.7 0.0 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase DUF4604 PF15377.6 EKX38110.1 - 0.00086 19.8 22.9 0.02 15.4 22.9 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4604) Cep57_CLD_2 PF14197.6 EKX38113.1 - 0.018 15.1 11.2 0.13 12.4 11.2 2.4 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 GIT_CC PF16559.5 EKX38113.1 - 0.26 11.2 3.7 0.84 9.5 3.7 1.9 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor WD40 PF00400.32 EKX38114.1 - 1.8e-20 72.9 12.4 0.00039 21.1 0.0 11.1 12 0 0 12 12 12 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX38114.1 - 8.4e-09 35.6 0.0 0.58 10.5 0.0 5.6 5 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain HELP PF03451.14 EKX38114.1 - 2.4e-08 33.7 2.3 4.7e-07 29.6 2.3 2.4 1 1 0 1 1 1 1 HELP motif SRP19 PF01922.17 EKX38115.1 - 1.3e-24 86.9 0.1 1.5e-24 86.8 0.1 1.0 1 0 0 1 1 1 1 SRP19 protein Glyco_transf_41 PF13844.6 EKX38116.1 - 3e-44 151.3 0.2 2.6e-30 105.3 0.0 3.2 1 1 2 3 3 3 2 Glycosyl transferase family 41 TPR_11 PF13414.6 EKX38116.1 - 6.4e-26 89.8 2.2 2.1e-07 30.5 0.0 7.0 5 1 1 6 6 6 4 TPR repeat TPR_2 PF07719.17 EKX38116.1 - 1.6e-19 68.4 3.7 0.016 15.3 0.1 9.7 10 1 0 10 10 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 EKX38116.1 - 6e-17 60.7 14.4 0.0059 16.9 0.1 7.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 EKX38116.1 - 1.3e-14 53.3 10.2 0.016 15.0 0.0 8.9 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 EKX38116.1 - 3.9e-11 42.8 12.0 0.099 13.5 0.0 8.6 5 3 4 9 9 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX38116.1 - 5.2e-11 42.9 10.0 0.09 13.3 0.0 6.1 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EKX38116.1 - 5.2e-10 38.7 9.0 0.018 15.2 0.0 8.1 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX38116.1 - 3e-09 37.4 17.4 0.0038 17.8 0.0 6.5 7 2 2 9 9 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 EKX38116.1 - 3e-09 37.0 16.5 0.0055 17.0 0.2 6.2 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 EKX38116.1 - 2.5e-06 27.2 26.8 0.3 11.0 0.1 8.7 9 0 0 9 9 9 2 Tetratricopeptide repeat TOM20_plant PF06552.12 EKX38116.1 - 2.6e-06 27.3 0.0 0.0062 16.3 0.0 3.3 2 2 0 2 2 2 2 Plant specific mitochondrial import receptor subunit TOM20 TPR_21 PF09976.9 EKX38116.1 - 2e-05 24.4 6.7 0.0033 17.2 0.6 3.8 3 1 1 4 4 3 2 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 EKX38116.1 - 0.00039 20.9 6.4 31 5.5 0.0 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 EKX38116.1 - 0.00091 19.3 7.6 3.1 8.0 0.1 6.1 5 1 2 7 7 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX38116.1 - 0.0083 16.3 3.0 17 5.7 0.0 4.4 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EKX38116.1 - 0.009 16.0 14.5 11 6.3 0.1 7.8 7 1 1 8 8 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 EKX38116.1 - 0.011 16.3 5.4 0.25 12.1 0.1 4.1 4 0 0 4 4 2 0 Tetratricopeptide repeat DUF4919 PF16266.5 EKX38116.1 - 0.2 11.6 1.3 0.62 10.0 0.3 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4919) Spore_III_AB PF09548.10 EKX38116.1 - 0.32 11.1 2.2 3.8 7.6 0.2 3.5 3 1 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Ribosomal_L33 PF00471.20 EKX38117.1 - 1e-13 51.5 0.1 1.2e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 HNH_4 PF13395.6 EKX38118.1 - 1.9e-05 24.5 0.0 4.1e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease HNH_5 PF14279.6 EKX38118.1 - 0.019 14.8 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 HNH endonuclease Mito_carr PF00153.27 EKX38119.1 - 2.7e-46 155.4 7.6 7.9e-22 77.0 0.1 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EKX38119.1 - 0.0035 16.6 0.2 0.015 14.5 0.0 1.9 2 0 0 2 2 2 1 Gammaproteobacterial serine protease GH43_C2 PF17851.1 EKX38119.1 - 1.5 8.5 3.2 2.7 7.6 1.0 2.0 1 1 1 2 2 2 0 Beta xylosidase C-terminal Concanavalin A-like domain EF-hand_1 PF00036.32 EKX38121.1 - 1.9e-06 27.0 1.3 5.2e-06 25.6 1.3 1.8 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 EKX38121.1 - 1.5e-05 24.2 1.8 3.8e-05 23.0 1.8 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EKX38121.1 - 0.00011 22.5 0.1 0.00023 21.6 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX38121.1 - 0.00019 21.1 1.2 0.00065 19.4 1.2 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 EKX38121.1 - 0.0054 16.6 0.2 0.012 15.4 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair Lipocalin_3 PF12702.7 EKX38122.1 - 0.023 14.8 1.1 0.22 11.7 0.0 3.2 3 0 0 3 3 3 0 Lipocalin-like Dus PF01207.17 EKX38123.1 - 2e-51 175.0 0.6 6.3e-51 173.3 0.6 1.7 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) 6PF2K PF01591.18 EKX38124.1 - 6.4e-69 231.7 0.0 9.1e-69 231.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.6 EKX38124.1 - 1.9e-08 34.6 0.0 2.7e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EKX38124.1 - 0.0047 16.4 0.0 0.0055 16.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CARD PF00619.21 EKX38124.1 - 0.039 14.0 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 Caspase recruitment domain DUF594 PF04578.13 EKX38125.1 - 1.4e-08 34.2 5.1 0.17 11.4 0.1 3.7 3 0 0 3 3 3 3 Protein of unknown function, DUF594 Macro PF01661.21 EKX38125.1 - 1e-05 25.6 1.0 8.3 6.5 0.0 4.7 5 0 0 5 5 5 1 Macro domain DUF3014 PF11219.8 EKX38125.1 - 7.3e-05 23.1 0.7 9.5 6.5 0.0 3.8 4 0 0 4 4 4 3 Protein of unknown function (DUF3014) ADH_N_2 PF16884.5 EKX38125.1 - 0.0011 18.9 0.0 42 4.1 0.0 4.3 4 0 0 4 4 4 0 N-terminal domain of oxidoreductase PriCT_1 PF08708.11 EKX38125.1 - 0.0061 16.3 3.9 50 3.7 0.1 4.7 5 0 0 5 5 5 0 Primase C terminal 1 (PriCT-1) Sec20 PF03908.13 EKX38125.1 - 0.023 14.6 0.0 78 3.3 0.0 3.5 3 0 0 3 3 3 0 Sec20 Med17 PF10156.9 EKX38125.1 - 0.031 13.0 5.2 0.063 12.0 5.2 1.5 1 0 0 1 1 1 0 Subunit 17 of Mediator complex RNA_pol_Rpc4 PF05132.14 EKX38125.1 - 0.13 12.7 0.2 0.25 11.8 0.2 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 RRN3 PF05327.11 EKX38125.1 - 0.24 9.9 3.1 0.39 9.2 3.1 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF3262 PF11660.8 EKX38125.1 - 8.1 6.9 14.1 54 4.3 0.4 4.9 4 1 0 4 4 4 0 Protein of unknown function (DUF3262) Ion_trans PF00520.31 EKX38126.1 - 3.5e-99 331.0 101.9 1.4e-28 99.8 15.2 4.1 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 EKX38126.1 - 7.6e-05 21.6 70.4 8.9e-05 21.3 15.5 6.4 5 1 0 5 5 5 4 Polycystin cation channel GPHH PF16905.5 EKX38126.1 - 0.00028 20.6 0.0 0.001 18.8 0.0 1.9 2 0 0 2 2 2 1 Voltage-dependent L-type calcium channel, IQ-associated Papilin_u7 PF16626.5 EKX38126.1 - 0.054 14.1 0.4 0.2 12.3 0.4 2.0 1 0 0 1 1 1 0 Linking region between Kunitz_BPTI and I-set on papilin DUF4234 PF14018.6 EKX38126.1 - 3.6 7.8 10.5 0.71 10.0 0.4 4.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4234) MIP PF00230.20 EKX38127.1 - 2.7e-19 69.8 4.5 2e-10 40.7 0.1 2.1 2 0 0 2 2 2 2 Major intrinsic protein Autoind_bind PF03472.15 EKX38127.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Autoinducer binding domain Sbi-IV PF11621.8 EKX38127.1 - 0.37 11.2 4.9 12 6.3 0.2 2.4 2 0 0 2 2 2 0 C3 binding domain 4 of IgG-bind protein SBI Mito_carr PF00153.27 EKX38128.1 - 3.3e-43 145.5 0.6 3.2e-15 55.8 0.0 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein NT-C2 PF10358.9 EKX38129.1 - 7.8e-06 25.7 0.3 2.7e-05 23.9 0.1 1.9 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins TPR_1 PF00515.28 EKX38130.1 - 0.0011 18.7 0.7 0.06 13.2 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX38130.1 - 0.0023 18.4 0.8 0.022 15.2 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX38130.1 - 0.0082 16.2 0.1 5.9 7.3 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat FKBP_C PF00254.28 EKX38130.1 - 0.061 13.6 0.0 0.53 10.6 0.0 2.4 2 0 0 2 2 2 0 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2481 PF10654.9 EKX38130.1 - 0.097 12.7 1.7 25 4.9 0.0 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2481) TPR_16 PF13432.6 EKX38130.1 - 0.1 13.3 0.0 3.3 8.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat PhoLip_ATPase_C PF16212.5 EKX38131.1 - 4e-54 184.0 16.0 4e-54 184.0 16.0 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EKX38131.1 - 4.2e-17 61.6 6.0 9.8e-17 60.4 6.0 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EKX38131.1 - 1.9e-12 47.1 0.5 1.2e-11 44.6 0.0 2.4 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EKX38131.1 - 2.5e-12 47.5 0.0 2.5e-07 31.2 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EKX38131.1 - 1.9e-06 27.5 0.0 1.9e-06 27.5 0.0 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EKX38131.1 - 0.026 14.2 0.1 0.076 12.7 0.1 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Aminotran_1_2 PF00155.21 EKX38132.1 - 7.6e-39 133.9 0.0 1e-38 133.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PG_binding_4 PF12229.8 EKX38132.1 - 0.0086 16.3 0.0 0.032 14.5 0.0 2.0 2 0 0 2 2 2 1 Putative peptidoglycan binding domain EF-hand_1 PF00036.32 EKX38133.1 - 1.4e-15 55.6 4.8 7.7e-05 22.0 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EKX38133.1 - 6.7e-14 50.6 2.8 0.0024 17.7 0.2 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 EKX38133.1 - 5.8e-12 45.9 11.4 1.4e-06 28.6 1.4 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EKX38133.1 - 1.9e-11 43.6 3.4 0.0067 16.3 0.4 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EKX38133.1 - 7.8e-09 34.6 4.1 0.042 13.4 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 EKX38133.1 - 0.0011 18.9 3.3 0.22 11.5 0.1 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EKX38133.1 - 0.0021 18.4 1.7 2.1 8.7 0.2 2.9 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EKX38133.1 - 0.0026 18.1 0.3 0.48 10.8 0.0 2.5 2 1 0 2 2 2 1 EF-hand domain EF-hand_13 PF17958.1 EKX38133.1 - 0.046 13.5 0.0 0.13 12.0 0.0 1.8 1 1 0 1 1 1 0 EF-hand domain EGF_CA PF07645.15 EKX38135.1 - 2.2e-11 43.8 26.2 2.1e-08 34.2 8.7 8.1 8 3 2 10 10 10 2 Calcium-binding EGF domain EGF_3 PF12947.7 EKX38135.1 - 9e-10 38.6 20.1 5.5e-07 29.7 9.9 8.8 9 1 1 10 10 10 2 EGF domain TSP_1 PF00090.19 EKX38135.1 - 2.6e-05 24.3 6.5 2.6e-05 24.3 6.5 6.5 6 0 0 6 6 6 3 Thrombospondin type 1 domain cEGF PF12662.7 EKX38135.1 - 0.00058 19.7 3.5 0.00058 19.7 3.5 8.0 8 0 0 8 8 8 2 Complement Clr-like EGF-like Ephrin_rec_like PF07699.13 EKX38135.1 - 0.0026 17.5 58.8 0.16 11.8 0.2 7.2 5 1 0 5 5 5 3 Putative ephrin-receptor like hEGF PF12661.7 EKX38135.1 - 0.0027 18.3 2.0 0.0027 18.3 2.0 8.4 8 0 0 8 8 8 2 Human growth factor-like EGF EGF PF00008.27 EKX38135.1 - 0.003 17.8 16.4 0.0032 17.7 5.8 8.2 9 1 0 9 9 9 2 EGF-like domain RMI1_N PF08585.12 EKX38136.1 - 5.2e-23 81.9 8.2 1.6e-17 64.0 0.4 3.4 2 1 1 3 3 3 2 RecQ mediated genome instability protein DUF4554 PF15091.6 EKX38136.1 - 0.063 12.2 3.3 3.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4554) ADH_zinc_N_2 PF13602.6 EKX38138.1 - 6e-10 40.3 0.0 2.7e-08 34.9 0.0 2.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EKX38138.1 - 7.5e-06 25.9 0.0 1.7e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EKX38138.1 - 3.9e-05 23.5 0.0 8.4e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Exonuc_VII_L PF02601.15 EKX38139.1 - 0.032 13.8 0.2 0.041 13.5 0.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit MMR_HSR1 PF01926.23 EKX38140.1 - 2.9e-15 56.3 0.0 6e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EKX38140.1 - 4.2e-05 23.5 0.0 0.011 15.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EKX38140.1 - 0.00071 19.2 0.0 0.089 12.3 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EKX38140.1 - 0.0017 18.4 0.0 0.036 14.1 0.0 2.2 1 1 1 2 2 2 1 Dynamin family SRPRB PF09439.10 EKX38140.1 - 0.0045 16.4 0.0 0.0079 15.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EKX38140.1 - 0.006 16.1 0.0 0.018 14.6 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B FtsK_SpoIIIE PF01580.18 EKX38140.1 - 0.028 13.8 0.0 0.052 12.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Wzy_C_2 PF11846.8 EKX38140.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal UCH PF00443.29 EKX38141.1 - 2e-55 188.1 0.9 2.9e-55 187.6 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EKX38141.1 - 5.1e-23 82.2 0.0 1.9e-22 80.3 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3833 PF12915.7 EKX38141.1 - 0.027 14.0 0.4 0.96 9.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3833) FYRN PF05964.14 EKX38142.1 - 4.5e-08 32.8 0.0 1e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 EKX38142.1 - 1.1e-07 31.9 0.0 5e-07 29.8 0.0 2.2 2 0 0 2 2 2 1 F/Y rich C-terminus CTD_bind PF04818.13 EKX38142.1 - 2.8e-06 28.0 0.2 4.5e-05 24.2 0.0 3.2 4 0 0 4 4 4 1 RNA polymerase II-binding domain. Agenet PF05641.12 EKX38142.1 - 0.00039 20.8 3.7 0.0068 16.9 0.1 3.8 3 0 0 3 3 3 1 Agenet domain TUDOR_5 PF18359.1 EKX38142.1 - 0.001 18.7 0.1 0.0033 17.1 0.1 1.9 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 Bromodomain PF00439.25 EKX38142.1 - 0.0066 16.5 0.4 0.27 11.3 0.1 2.8 2 0 0 2 2 2 1 Bromodomain LysM PF01476.20 EKX38142.1 - 0.02 14.9 0.0 0.18 11.9 0.0 2.5 2 0 0 2 2 2 0 LysM domain 53-BP1_Tudor PF09038.10 EKX38142.1 - 0.048 13.6 0.1 0.27 11.2 0.1 2.2 2 0 0 2 2 2 0 Tumour suppressor p53-binding protein-1 Tudor Tudor-knot PF11717.8 EKX38142.1 - 0.065 13.1 1.2 0.61 10.0 0.0 3.1 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain MBT PF02820.18 EKX38142.1 - 0.089 13.1 0.0 0.33 11.3 0.0 1.9 1 0 0 1 1 1 0 mbt repeat RWP-RK PF02042.15 EKX38143.1 - 5.9e-14 51.8 0.0 1e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX38144.1 - 6.5e-14 51.6 0.0 1.1e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_Mga PF08280.11 EKX38144.1 - 0.21 11.7 0.0 0.67 10.0 0.0 1.8 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain zf-DNL PF05180.12 EKX38145.1 - 4.1e-23 81.1 1.8 4.6e-23 80.9 1.8 1.1 1 0 0 1 1 1 1 DNL zinc finger Elf1 PF05129.13 EKX38145.1 - 0.0053 16.8 1.1 0.0054 16.8 1.1 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.6 EKX38145.1 - 0.023 15.1 0.6 0.025 14.9 0.6 1.1 1 0 0 1 1 1 0 Restriction alleviation protein Lar ZZ PF00569.17 EKX38145.1 - 0.032 14.0 0.8 4.5 7.2 0.1 2.3 2 0 0 2 2 2 0 Zinc finger, ZZ type eIF-5_eIF-2B PF01873.17 EKX38145.1 - 0.056 13.3 1.2 0.073 13.0 1.2 1.2 1 0 0 1 1 1 0 Domain found in IF2B/IF5 TFIIS_C PF01096.18 EKX38145.1 - 0.2 11.6 6.3 0.17 11.8 3.2 2.3 2 1 1 3 3 3 0 Transcription factor S-II (TFIIS) PHD_2 PF13831.6 EKX38145.1 - 0.49 10.0 5.7 3.7 7.2 0.3 2.8 3 0 0 3 3 3 0 PHD-finger Peptidase_C14 PF00656.22 EKX38146.1 - 3.5e-16 59.9 0.0 1.7e-15 57.6 0.0 2.0 1 1 0 1 1 1 1 Caspase domain TcfC PF16967.5 EKX38146.1 - 0.2 11.2 0.0 0.42 10.1 0.0 1.4 1 0 0 1 1 1 0 E-set like domain C2 PF00168.30 EKX38147.1 - 4.6e-50 168.2 0.0 2.9e-25 88.5 0.0 2.3 2 0 0 2 2 2 2 C2 domain DUF2393 PF09624.10 EKX38147.1 - 0.19 11.7 0.1 1.6 8.7 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2393) TPR_12 PF13424.6 EKX38148.1 - 6.4e-26 90.5 8.9 2.3e-13 50.2 1.8 3.1 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 EKX38148.1 - 6.8e-22 76.7 2.8 1.3e-07 31.2 0.1 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 EKX38148.1 - 2.5e-11 42.9 2.5 0.00012 21.7 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX38148.1 - 5.1e-10 38.7 5.9 0.028 14.5 0.3 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX38148.1 - 1.1e-09 37.6 4.7 0.051 13.6 0.1 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX38148.1 - 5.1e-09 36.0 1.1 6.4e-09 35.6 1.1 1.1 1 0 0 1 1 1 1 MalT-like TPR region TPR_8 PF13181.6 EKX38148.1 - 1.2e-08 34.5 1.9 0.019 15.2 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX38148.1 - 8.2e-08 32.8 2.8 0.21 12.3 0.1 3.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX38148.1 - 8.2e-05 23.1 5.1 1.8 9.6 0.1 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 EKX38148.1 - 0.00032 21.1 1.1 13 6.7 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 EKX38148.1 - 0.00043 20.5 0.4 1.7 9.2 0.0 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX38148.1 - 0.00078 19.1 2.5 6.5 6.5 0.0 4.0 4 0 0 4 4 4 2 TPR repeat RPN7 PF10602.9 EKX38148.1 - 0.0036 17.0 0.2 9.2 5.9 0.0 3.1 2 1 1 3 3 3 1 26S proteasome subunit RPN7 PPR PF01535.20 EKX38148.1 - 0.094 13.0 0.0 20 5.7 0.0 3.2 3 0 0 3 3 3 0 PPR repeat TPR_6 PF13174.6 EKX38148.1 - 1.7 9.4 5.4 7.1 7.5 0.4 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Ank_5 PF13857.6 EKX38149.1 - 1.9e-18 66.2 0.1 5.6e-09 36.1 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX38149.1 - 2.3e-18 65.7 0.8 6.7e-07 29.5 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EKX38149.1 - 3.1e-18 65.9 0.0 6.8e-10 39.3 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX38149.1 - 3.5e-17 62.7 0.0 5.9e-10 39.6 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX38149.1 - 1.2e-16 59.1 0.3 4.6e-06 26.6 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat TPR_17 PF13431.6 EKX38151.1 - 1.4e-19 69.0 3.0 0.015 15.7 0.1 6.0 7 0 0 7 7 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 EKX38151.1 - 1.3e-18 65.9 7.6 0.00021 21.0 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EKX38151.1 - 2.3e-18 64.7 11.9 0.002 18.1 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 EKX38151.1 - 2.8e-16 58.3 6.8 0.0012 18.9 0.0 5.8 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 EKX38151.1 - 3.7e-14 52.8 14.4 0.00066 19.9 0.2 4.5 2 2 1 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 EKX38151.1 - 1.4e-13 50.4 10.3 0.051 14.4 0.1 6.2 1 1 5 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 EKX38151.1 - 4e-11 43.4 4.3 0.00019 22.0 0.1 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX38151.1 - 9.3e-11 41.2 2.1 0.00014 21.5 0.1 4.2 2 1 2 4 4 4 3 TPR repeat TPR_19 PF14559.6 EKX38151.1 - 9.8e-10 38.8 7.3 0.0014 19.1 0.4 4.3 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX38151.1 - 3.4e-07 29.9 9.9 0.46 10.4 0.2 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX38151.1 - 5e-07 29.3 8.0 3.3 8.0 0.2 6.4 5 1 1 6 6 6 1 Tetratricopeptide repeat Coatomer_E PF04733.14 EKX38151.1 - 0.00074 19.0 0.8 1.5 8.2 0.1 3.4 1 1 3 4 4 4 2 Coatomer epsilon subunit TPR_6 PF13174.6 EKX38151.1 - 0.00092 19.7 5.7 1.8 9.4 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPPII_N PF12583.8 EKX38151.1 - 0.00092 19.8 7.5 3.8 8.1 0.6 4.3 3 2 1 4 4 4 2 Tripeptidyl peptidase II N terminal Tcf25 PF04910.14 EKX38151.1 - 0.0012 18.0 0.2 2.9 6.9 0.0 3.5 1 1 3 4 4 4 1 Transcriptional repressor TCF25 DUF4919 PF16266.5 EKX38151.1 - 0.006 16.5 0.2 0.67 9.9 0.0 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF4919) TPR_MalT PF17874.1 EKX38151.1 - 0.02 14.3 2.4 0.12 11.7 0.7 2.4 1 1 2 3 3 3 0 MalT-like TPR region TPR_20 PF14561.6 EKX38151.1 - 0.17 12.2 4.0 2.7 8.4 0.4 3.8 2 2 3 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 EKX38151.1 - 0.18 12.5 5.0 12 6.9 0.4 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Ank_4 PF13637.6 EKX38153.1 - 2.7e-07 31.0 0.0 4.1e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX38153.1 - 4.6e-07 30.0 0.0 7.7e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX38153.1 - 8.1e-06 26.1 0.2 0.0086 16.5 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EKX38153.1 - 3.4e-05 24.4 0.0 4.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX38153.1 - 0.00012 22.2 0.0 0.00033 20.9 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeat ArfGap PF01412.18 EKX38155.1 - 0.0019 18.2 0.1 0.0036 17.4 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ArfGap PF01412.18 EKX38156.1 - 2.4e-30 105.0 0.2 2.7e-30 104.9 0.2 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Paired_CXXCH_1 PF09699.10 EKX38156.1 - 0.072 12.9 2.1 0.14 11.9 0.1 2.3 3 0 0 3 3 3 0 Doubled CXXCH motif (Paired_CXXCH_1) Wzy_C_2 PF11846.8 EKX38157.1 - 0.0017 18.3 0.2 0.0017 18.3 0.2 2.5 2 1 1 3 3 3 1 Virulence factor membrane-bound polymerase, C-terminal OppC_N PF12911.7 EKX38157.1 - 0.0091 15.9 0.2 0.02 14.9 0.2 1.5 1 0 0 1 1 1 1 N-terminal TM domain of oligopeptide transport permease C DUF3037 PF11236.8 EKX38157.1 - 0.24 11.9 8.8 0.27 11.7 1.1 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF3037) DUF148 PF02520.17 EKX38157.1 - 0.75 9.9 26.7 4.2 7.5 2.2 5.0 3 2 2 5 5 5 0 Domain of unknown function DUF148 DIL PF01843.19 EKX38157.1 - 1.9 8.8 11.5 1.1 9.6 1.0 3.5 3 2 1 4 4 4 0 DIL domain Condensin2nSMC PF12422.8 EKX38157.1 - 2.2 8.5 6.8 0.9 9.7 0.2 2.9 2 1 1 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit Peroxin-13_N PF04088.13 EKX38157.1 - 4.3 7.6 9.0 0.61 10.4 2.5 2.8 1 1 0 2 2 2 0 Peroxin 13, N-terminal region Death PF00531.22 EKX38157.1 - 5.6 7.2 7.9 1.3 9.2 0.4 3.3 2 2 1 3 3 3 0 Death domain Rieske PF00355.26 EKX38158.1 - 6.2e-20 70.9 0.2 1.1e-19 70.2 0.2 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 EKX38158.1 - 1.8e-17 63.3 0.7 3.7e-17 62.2 0.2 1.7 2 0 0 2 2 2 1 Pheophorbide a oxygenase DnaJ_C PF01556.18 EKX38159.1 - 1.1e-30 106.7 0.0 1.2e-30 106.5 0.0 1.0 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 EKX38159.1 - 1.4e-13 51.0 21.5 1.2e-11 44.8 10.4 1.8 1 1 1 2 2 2 2 DnaJ central domain Anti-TRAP PF15777.5 EKX38159.1 - 9.6e-06 25.5 14.1 0.00017 21.5 4.2 3.2 1 1 2 3 3 3 2 Tryptophan RNA-binding attenuator protein inhibitory protein TackOD1 PF18551.1 EKX38159.1 - 0.0012 18.6 9.4 0.08 12.6 2.4 2.2 1 1 1 2 2 2 2 Thaumarchaeal output domain 1 DUF5351 PF17302.2 EKX38159.1 - 0.01 16.0 15.7 3.1 8.1 0.6 4.0 2 1 2 4 4 4 0 Family of unknown function (DUF5351) zinc_ribbon_9 PF14369.6 EKX38159.1 - 0.086 13.1 11.7 5.4 7.4 0.1 3.5 2 1 1 3 3 3 0 zinc-ribbon DZR PF12773.7 EKX38159.1 - 0.4 10.8 9.1 0.8 9.8 9.1 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf_CopZ PF18423.1 EKX38159.1 - 3.7 7.6 18.0 2.1 8.4 0.6 4.2 3 1 1 4 4 4 0 Zinc binding domain HypA PF01155.19 EKX38159.1 - 5.5 7.1 11.1 9.9 6.2 5.8 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF35_N PF12172.8 EKX38159.1 - 5.7 6.9 14.2 3.8 7.5 0.2 3.5 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) MFS_1 PF07690.16 EKX38160.1 - 3.2e-44 151.3 46.4 1.4e-42 145.9 30.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EKX38160.1 - 6.3e-08 31.9 10.5 1.1e-07 31.1 9.8 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 EKX38160.1 - 0.00024 19.6 7.1 0.0036 15.7 0.0 2.9 3 1 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Patatin PF01734.22 EKX38161.1 - 1.7e-13 51.2 1.1 8e-13 49.0 1.1 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase Glucosamine_iso PF01182.20 EKX38163.1 - 5.2e-29 101.7 0.0 2.9e-28 99.3 0.0 2.0 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Beta_helix PF13229.6 EKX38163.1 - 0.00055 19.8 3.8 0.0012 18.7 3.8 1.5 1 1 0 1 1 1 1 Right handed beta helix region PrsW-protease PF13367.6 EKX38164.1 - 3.5e-14 52.7 5.0 3.5e-14 52.7 5.0 1.9 2 0 0 2 2 2 1 PrsW family intramembrane metalloprotease Endonuc-BsobI PF09194.10 EKX38165.1 - 0.099 11.8 0.1 0.16 11.1 0.1 1.2 1 0 0 1 1 1 0 Restriction endonuclease BsobI AT_hook PF02178.19 EKX38166.1 - 0.0041 16.8 15.9 0.1 12.5 3.6 2.8 2 0 0 2 2 2 2 AT hook motif Tombus_P33 PF08500.10 EKX38166.1 - 0.27 11.2 3.1 0.33 10.9 3.1 1.3 1 0 0 1 1 1 0 Tombusvirus p33 UPF0560 PF10577.9 EKX38166.1 - 7.2 5.0 10.9 7.9 4.8 10.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 RRM_1 PF00076.22 EKX38167.1 - 7e-18 64.2 0.0 1.1e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EKX38167.1 - 0.0034 17.5 0.0 0.0075 16.4 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif Limkain-b1 PF11608.8 EKX38167.1 - 0.0085 16.1 0.2 0.031 14.4 0.2 1.9 1 1 0 1 1 1 1 Limkain b1 SUR7 PF06687.12 EKX38168.1 - 0.075 12.6 0.1 0.084 12.5 0.1 1.1 1 0 0 1 1 1 0 SUR7/PalI family DUF3488 PF11992.8 EKX38168.1 - 0.13 11.1 2.0 0.18 10.7 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) preSET_CXC PF18264.1 EKX38169.1 - 0.15 12.6 3.3 0.26 11.8 3.3 1.3 1 0 0 1 1 1 0 CXC domain HMG_box PF00505.19 EKX38170.1 - 4e-27 94.4 22.8 2e-13 50.5 2.7 2.2 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EKX38170.1 - 1.3e-19 70.6 18.7 2.3e-10 40.9 10.7 2.3 2 0 0 2 2 2 2 HMG-box domain CHDNT PF08073.12 EKX38170.1 - 0.00022 21.1 2.4 0.0072 16.3 0.4 2.4 2 0 0 2 2 2 1 CHDNT (NUC034) domain Apo-CII PF05355.11 EKX38170.1 - 0.044 13.9 2.3 0.24 11.6 0.5 2.2 2 0 0 2 2 2 0 Apolipoprotein C-II PRELI PF04707.14 EKX38171.1 - 1.5e-12 47.6 0.3 2.2e-12 47.1 0.3 1.2 1 0 0 1 1 1 1 PRELI-like family DoxX_2 PF13564.6 EKX38172.1 - 1.1e-06 28.7 4.8 3.3e-06 27.1 2.1 2.4 2 0 0 2 2 2 1 DoxX-like family CENP-F_N PF10481.9 EKX38173.1 - 0.016 14.9 0.2 0.025 14.2 0.2 1.3 1 0 0 1 1 1 0 Cenp-F N-terminal domain DUF16 PF01519.16 EKX38173.1 - 0.12 12.8 0.0 0.32 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF16 Ax_dynein_light PF10211.9 EKX38174.1 - 2.7e-86 288.3 13.2 3.2e-86 288.1 13.2 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain Rota_NSP3 PF01665.16 EKX38174.1 - 0.16 11.1 3.5 0.23 10.5 3.5 1.2 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 Striatin PF08232.12 EKX38174.1 - 0.2 12.3 13.3 0.1 13.2 8.7 2.1 2 0 0 2 2 2 0 Striatin family FapA PF03961.13 EKX38174.1 - 0.66 8.5 7.5 0.97 8.0 7.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4094 PF13334.6 EKX38174.1 - 1 9.8 6.6 0.37 11.3 3.2 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) PCRF PF03462.18 EKX38174.1 - 1.1 9.1 7.2 1.9 8.3 7.2 1.4 1 0 0 1 1 1 0 PCRF domain Fungal_TACC PF12709.7 EKX38174.1 - 4.8 7.7 16.4 0.57 10.7 3.3 3.0 2 2 1 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins Spc24 PF08286.11 EKX38174.1 - 4.8 7.5 12.3 2 8.7 9.6 1.8 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 RIBIOP_C PF04950.12 EKX38175.1 - 0.06 12.8 0.0 0.074 12.5 0.0 1.1 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Ribosomal_L21p PF00829.21 EKX38176.1 - 4.8e-31 107.0 0.7 5.7e-31 106.8 0.7 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein MORN PF02493.20 EKX38177.1 - 2e-18 65.1 39.3 0.0009 19.0 2.1 7.1 7 0 0 7 7 7 6 MORN repeat Pkinase PF00069.25 EKX38178.1 - 4.9e-74 249.0 0.0 5.5e-74 248.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX38178.1 - 3.8e-37 128.0 0.0 4.6e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX38178.1 - 3e-07 30.0 0.0 5.4e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EKX38178.1 - 2.6e-05 23.2 0.0 6.2e-05 21.9 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 EKX38178.1 - 0.0063 16.2 0.2 1.2 8.7 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_C PF00433.24 EKX38178.1 - 0.024 15.3 1.0 0.048 14.4 1.0 1.5 1 0 0 1 1 1 0 Protein kinase C terminal domain APH PF01636.23 EKX38178.1 - 0.044 13.7 0.0 0.096 12.6 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 EKX38178.1 - 0.067 12.8 0.0 0.24 11.0 0.0 1.8 2 1 0 3 3 3 0 RIO1 family Haspin_kinase PF12330.8 EKX38178.1 - 0.11 11.5 0.1 0.18 10.7 0.1 1.3 1 1 0 1 1 1 0 Haspin like kinase domain NPV_P10 PF05531.12 EKX38179.1 - 1.1 9.8 11.9 1.4 9.4 0.6 4.2 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 EKX38180.1 - 0.00039 20.7 6.2 0.00039 20.7 6.2 4.0 3 1 1 4 4 4 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3450 PF11932.8 EKX38180.1 - 0.0079 15.5 7.0 0.0079 15.5 7.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) DUF573 PF04504.14 EKX38180.1 - 0.027 15.1 2.0 0.027 15.1 2.0 3.3 2 1 1 3 3 3 0 Protein of unknown function, DUF573 Prefoldin_2 PF01920.20 EKX38180.1 - 0.044 13.7 1.1 0.044 13.7 1.1 4.7 3 2 2 5 5 5 0 Prefoldin subunit Syntaxin PF00804.25 EKX38180.1 - 0.099 12.3 24.2 0.58 9.8 8.9 2.6 2 1 0 2 2 2 0 Syntaxin Tropomyosin PF00261.20 EKX38180.1 - 0.1 11.9 34.1 0.09 12.1 11.9 2.3 2 0 0 2 2 2 0 Tropomyosin BEX PF04538.12 EKX38180.1 - 0.18 12.4 21.5 0.092 13.3 5.6 2.3 1 1 1 2 2 2 0 Brain expressed X-linked like family Baculo_PEP_C PF04513.12 EKX38180.1 - 0.2 11.7 5.1 0.76 9.8 0.9 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 EKX38180.1 - 0.41 10.9 6.8 2.4 8.5 0.3 3.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Fez1 PF06818.15 EKX38180.1 - 0.68 10.4 34.3 13 6.2 34.1 2.1 1 1 0 1 1 1 0 Fez1 Tropomyosin_1 PF12718.7 EKX38180.1 - 0.77 9.9 36.5 0.15 12.2 11.9 2.1 2 0 0 2 2 2 0 Tropomyosin like APG17 PF04108.12 EKX38180.1 - 1.5 7.9 26.4 0.8 8.7 4.3 2.6 2 1 1 3 3 3 0 Autophagy protein Apg17 Fib_alpha PF08702.10 EKX38180.1 - 1.6 8.9 30.1 2.1 8.5 9.4 3.2 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 EKX38180.1 - 2.3 7.0 36.0 1 8.2 13.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein TMPIT PF07851.13 EKX38180.1 - 2.3 7.4 29.7 2.2 7.4 11.0 2.1 1 1 1 2 2 2 0 TMPIT-like protein CENP-F_leu_zip PF10473.9 EKX38180.1 - 2.4 8.2 42.3 2.9 7.9 18.8 2.9 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Muted PF14942.6 EKX38180.1 - 2.8 8.3 34.5 0.13 12.6 10.8 2.9 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein DUF2894 PF11445.8 EKX38180.1 - 3 8.3 14.4 0.95 9.9 3.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) TolA_bind_tri PF16331.5 EKX38180.1 - 3.2 7.9 27.0 0.41 10.7 2.9 3.6 2 1 1 3 3 3 0 TolA binding protein trimerisation OmpH PF03938.14 EKX38180.1 - 3.8 7.8 34.2 0.51 10.7 8.7 2.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Atg14 PF10186.9 EKX38180.1 - 8.2 5.4 32.2 79 2.2 9.4 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pox_A14 PF05767.12 EKX38182.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Pkinase_Tyr PF07714.17 EKX38184.1 - 2.5e-58 197.4 0.0 5e-58 196.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX38184.1 - 2e-55 188.0 0.0 3.7e-55 187.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Beta_helix PF13229.6 EKX38184.1 - 1.4e-13 51.0 0.6 2.4e-13 50.3 0.6 1.3 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 EKX38184.1 - 4.9e-06 26.0 0.3 7.8e-06 25.3 0.3 1.2 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Pkinase_fungal PF17667.1 EKX38184.1 - 0.00033 19.6 0.0 0.0014 17.5 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase zf-RING_10 PF16685.5 EKX38184.1 - 0.00058 19.9 6.2 0.00058 19.9 6.2 2.2 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 EKX38184.1 - 0.0011 18.9 10.2 0.0028 17.7 10.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EKX38184.1 - 0.003 17.4 6.8 0.003 17.4 6.8 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX38184.1 - 0.0045 17.3 8.9 0.0045 17.3 8.9 2.1 2 0 0 2 2 1 1 Ring finger domain APH PF01636.23 EKX38184.1 - 0.0052 16.7 0.0 0.15 11.9 0.0 2.4 1 1 0 2 2 2 1 Phosphotransferase enzyme family ABC1 PF03109.16 EKX38184.1 - 0.008 16.3 0.0 0.024 14.8 0.0 1.8 1 0 0 1 1 1 1 ABC1 family zf-C3HC4_4 PF15227.6 EKX38184.1 - 0.016 15.3 11.1 0.016 15.3 11.1 1.9 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EKX38184.1 - 0.017 14.9 9.8 0.017 14.9 9.8 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PMC2NT PF08066.12 EKX38185.1 - 0.042 14.6 0.2 0.15 12.8 0.2 1.9 1 1 0 1 1 1 0 PMC2NT (NUC016) domain DUF2791 PF10923.8 EKX38185.1 - 0.052 12.4 0.1 0.065 12.1 0.1 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Metal_CEHH PF14455.6 EKX38185.1 - 0.13 11.8 0.3 0.19 11.3 0.3 1.2 1 0 0 1 1 1 0 Predicted metal binding domain NDK PF00334.19 EKX38186.1 - 9.2e-33 113.1 0.1 7.2e-32 110.2 0.1 1.8 1 1 0 1 1 1 1 Nucleoside diphosphate kinase ABC1 PF03109.16 EKX38188.1 - 1.3e-23 83.4 0.0 1.7e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 ABC1 family TPR_1 PF00515.28 EKX38189.1 - 2.1e-18 65.3 0.0 5.5e-08 32.3 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX38189.1 - 3.9e-17 60.9 0.2 2e-06 27.5 0.1 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX38189.1 - 2.3e-14 52.3 0.3 0.00058 19.9 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX38189.1 - 7.4e-10 38.3 1.1 0.03 14.0 0.1 3.1 2 1 1 3 3 3 3 TPR repeat TPR_16 PF13432.6 EKX38189.1 - 1.4e-08 35.3 0.2 0.00014 22.4 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX38189.1 - 6.4e-07 29.7 0.1 0.033 15.0 0.0 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX38189.1 - 1.3e-05 25.4 0.8 0.026 14.8 0.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX38189.1 - 0.00022 21.0 0.1 0.88 9.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX38189.1 - 0.0023 17.8 0.4 1.8 8.5 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX38189.1 - 0.0032 17.9 0.1 0.38 11.3 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 EKX38189.1 - 0.024 14.1 0.0 1 8.9 0.0 2.5 2 0 0 2 2 2 0 SHNi-TPR TPR_17 PF13431.6 EKX38189.1 - 0.035 14.5 1.1 7 7.3 0.0 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 EKX38189.1 - 0.047 13.8 1.7 3.8 7.7 0.5 2.6 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 EKX38189.1 - 0.34 10.9 0.1 0.34 10.9 0.1 2.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2529 PF10740.9 EKX38191.1 - 0.011 15.4 0.1 0.011 15.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2529) DUF1319 PF07028.11 EKX38191.1 - 0.016 15.4 0.3 0.019 15.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) Spc7 PF08317.11 EKX38191.1 - 0.051 12.5 0.3 0.065 12.1 0.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PAS_5 PF07310.13 EKX38191.1 - 0.11 12.3 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 PAS domain ACCA PF03255.14 EKX38191.1 - 0.12 12.3 0.3 0.13 12.1 0.3 1.1 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Pox_A_type_inc PF04508.12 EKX38191.1 - 1.3 9.0 5.9 2.3 8.2 0.4 2.9 2 1 0 2 2 2 0 Viral A-type inclusion protein repeat Yae1_N PF09811.9 EKX38192.1 - 0.08 12.7 2.1 3.3 7.5 0.2 2.3 2 0 0 2 2 2 0 Essential protein Yae1, N terminal Peptidase_M24 PF00557.24 EKX38193.1 - 2.2e-42 145.1 0.0 3.3e-42 144.5 0.0 1.3 1 1 0 1 1 1 1 Metallopeptidase family M24 RRM_1 PF00076.22 EKX38194.1 - 1.5e-31 108.0 0.0 5.5e-15 54.9 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EKX38194.1 - 0.00098 19.2 0.4 0.0087 16.2 0.2 2.5 1 1 1 2 2 2 1 RNA recognition motif RRM_occluded PF16842.5 EKX38194.1 - 0.09 12.6 0.0 2.3 8.1 0.0 2.4 2 1 0 2 2 2 0 Occluded RNA-recognition motif Peptidase_C97 PF05903.14 EKX38195.1 - 4.3e-26 91.5 0.0 9.1e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 PPPDE putative peptidase domain UBA_4 PF14555.6 EKX38195.1 - 4.1e-07 29.7 0.0 0.00093 19.0 0.0 2.5 2 0 0 2 2 2 2 UBA-like domain LRAT PF04970.13 EKX38195.1 - 0.15 12.4 0.1 0.32 11.3 0.1 1.5 1 0 0 1 1 1 0 Lecithin retinol acyltransferase TIG PF01833.24 EKX38196.1 - 3.6e-12 46.2 0.0 4.6e-09 36.2 0.1 3.3 2 1 0 2 2 2 2 IPT/TIG domain Laminin_G_3 PF13385.6 EKX38196.1 - 0.067 13.3 2.9 0.11 12.6 0.0 2.7 4 0 0 4 4 4 0 Concanavalin A-like lectin/glucanases superfamily Kinase-PPPase PF03618.14 EKX38197.1 - 5.5e-58 196.7 0.0 6.1e-58 196.6 0.0 1.0 1 0 0 1 1 1 1 Kinase/pyrophosphorylase NAD_binding_7 PF13241.6 EKX38197.1 - 0.19 12.1 0.1 2 8.9 0.1 2.4 3 0 0 3 3 3 0 Putative NAD(P)-binding Beta_helix PF13229.6 EKX38198.1 - 0.00014 21.8 0.1 0.00023 21.1 0.1 1.2 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 EKX38198.1 - 0.12 11.7 0.0 0.28 10.4 0.0 1.5 2 0 0 2 2 2 0 Periplasmic copper-binding protein (NosD) EzrA PF06160.12 EKX38198.1 - 0.83 7.7 35.2 0.095 10.9 9.7 3.2 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA KxDL PF10241.9 EKX38198.1 - 8 6.8 30.8 0.097 13.0 1.5 5.4 5 2 0 5 5 5 0 Uncharacterized conserved protein FA_desaturase PF00487.24 EKX38201.1 - 3.7e-37 128.6 18.0 5.2e-37 128.1 18.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase S-methyl_trans PF02574.16 EKX38202.1 - 4.7e-56 190.5 0.1 4e-46 158.0 0.0 2.0 1 1 1 2 2 2 2 Homocysteine S-methyltransferase LEAP-2 PF07359.11 EKX38202.1 - 0.0088 15.9 2.1 0.19 11.6 0.3 2.5 3 0 0 3 3 3 2 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) ACBP PF00887.19 EKX38203.1 - 1.4e-20 73.3 0.2 1.7e-20 73.0 0.2 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein Pkinase PF00069.25 EKX38204.1 - 3e-43 148.1 0.0 3.3e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX38204.1 - 1.3e-23 83.6 0.0 1.6e-23 83.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX38204.1 - 3.8e-06 25.9 0.0 4.9e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EKX38204.1 - 1.9e-05 24.1 0.0 3.9e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EKX38204.1 - 0.00019 20.9 0.0 0.00022 20.6 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX38204.1 - 0.0049 16.8 0.0 0.012 15.6 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EKX38204.1 - 0.0089 15.6 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.11 EKX38204.1 - 0.28 10.2 0.0 0.38 9.8 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Ank_4 PF13637.6 EKX38205.1 - 3.9e-12 46.4 0.8 3.6e-07 30.6 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX38205.1 - 2.6e-09 37.6 0.0 7.1e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX38205.1 - 5.6e-09 36.1 0.5 1.2e-08 35.0 0.5 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX38205.1 - 2.6e-05 24.2 0.6 0.015 15.7 0.1 3.8 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EKX38205.1 - 0.00021 21.6 1.9 0.0017 18.7 0.2 3.1 3 0 0 3 3 3 1 Ankyrin repeat TF_Zn_Ribbon PF08271.12 EKX38206.1 - 0.00036 20.0 4.4 0.00073 19.0 4.4 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding zf-RRN7 PF11781.8 EKX38206.1 - 0.002 17.7 0.9 0.004 16.8 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 OrfB_Zn_ribbon PF07282.11 EKX38206.1 - 0.0035 17.2 1.6 0.0071 16.3 1.6 1.5 1 0 0 1 1 1 1 Putative transposase DNA-binding domain DZR PF12773.7 EKX38206.1 - 0.0055 16.7 1.2 0.014 15.4 0.6 1.9 2 1 0 2 2 2 1 Double zinc ribbon zf-ribbon_3 PF13248.6 EKX38206.1 - 0.021 14.2 7.6 0.21 11.0 5.8 2.8 2 1 0 2 2 2 0 zinc-ribbon domain zf-IS66 PF13005.7 EKX38206.1 - 0.026 14.9 1.5 1.7 9.1 0.1 2.8 2 0 0 2 2 2 0 zinc-finger binding domain of transposase IS66 GFA PF04828.14 EKX38206.1 - 0.031 14.6 0.6 2.7 8.4 0.0 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme TackOD1 PF18551.1 EKX38206.1 - 0.056 13.1 0.3 0.096 12.4 0.3 1.3 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 zf_UBZ PF18439.1 EKX38206.1 - 0.11 12.1 1.1 4.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger UPF0547 PF10571.9 EKX38206.1 - 0.12 12.4 1.0 2.2 8.4 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.6 EKX38206.1 - 0.25 11.1 5.1 1.9 8.3 0.1 2.7 3 0 0 3 3 3 0 zinc-ribbon domain Auto_anti-p27 PF06677.12 EKX38206.1 - 0.39 10.9 1.8 8.5 6.6 1.9 2.3 1 1 1 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Prok-RING_1 PF14446.6 EKX38206.1 - 1 9.3 4.9 0.65 10.0 2.5 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Zn-ribbon_8 PF09723.10 EKX38206.1 - 1.1 9.5 4.5 6.3 7.0 0.8 2.4 1 1 2 3 3 3 0 Zinc ribbon domain YhfH PF14149.6 EKX38206.1 - 7.5 6.6 7.2 6 6.9 4.5 2.2 1 1 1 2 2 2 0 YhfH-like protein Arf PF00025.21 EKX38207.1 - 4.5e-26 91.3 0.4 5.5e-26 91.1 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EKX38207.1 - 8.7e-07 28.4 3.4 0.0088 15.2 0.5 2.8 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EKX38207.1 - 1.7e-06 27.6 0.1 2.1e-06 27.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EKX38207.1 - 2.3e-06 27.8 0.1 6.1e-06 26.5 0.1 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EKX38207.1 - 1.2e-05 25.0 0.1 3e-05 23.7 0.1 1.6 1 1 0 1 1 1 1 Ras family Mg_chelatase PF01078.21 EKX38207.1 - 0.00015 21.3 0.0 0.00025 20.5 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 EKX38207.1 - 0.00049 20.2 0.1 0.0031 17.6 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EKX38207.1 - 0.00054 20.3 0.0 0.0018 18.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EKX38207.1 - 0.00055 20.0 0.1 0.00068 19.6 0.1 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 EKX38207.1 - 0.00074 19.5 0.3 0.21 11.5 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EKX38207.1 - 0.00082 19.0 0.6 0.048 13.2 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EKX38207.1 - 0.005 16.3 1.1 0.52 9.7 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EKX38207.1 - 0.011 16.1 0.1 0.017 15.5 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 EKX38207.1 - 0.014 15.1 0.2 0.18 11.5 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pox_A32 PF04665.12 EKX38207.1 - 0.027 13.9 0.7 0.36 10.2 0.0 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_2 PF07724.14 EKX38207.1 - 0.03 14.5 0.1 0.063 13.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 EKX38207.1 - 0.035 13.8 0.1 0.71 9.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 EKX38207.1 - 0.038 14.2 0.0 0.079 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EKX38207.1 - 0.041 13.4 0.1 0.068 12.7 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EKX38207.1 - 0.043 14.3 0.1 0.056 14.0 0.1 1.5 1 1 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 EKX38207.1 - 0.078 12.2 0.5 2.3 7.4 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 EKX38207.1 - 0.093 12.6 0.1 0.22 11.4 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 EKX38207.1 - 0.1 12.7 0.1 0.15 12.2 0.1 1.4 1 1 0 1 1 1 0 AAA domain Peptidase_M41 PF01434.18 EKX38208.1 - 4.8e-66 222.3 0.5 1.2e-65 221.0 0.5 1.7 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EKX38208.1 - 1.7e-43 148.2 0.0 3.7e-43 147.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EKX38208.1 - 9.8e-11 41.3 0.1 2.6e-10 39.9 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EKX38208.1 - 2.2e-06 27.7 0.0 8.7e-06 25.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EKX38208.1 - 1.5e-05 24.8 0.0 5.4e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EKX38208.1 - 1.5e-05 24.4 0.0 3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 EKX38208.1 - 0.00011 22.7 0.4 0.013 15.8 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 EKX38208.1 - 0.003 17.3 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EKX38208.1 - 0.0034 16.8 1.1 0.028 13.8 0.6 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EKX38208.1 - 0.0034 17.6 0.2 0.11 12.8 0.2 2.8 2 1 0 2 2 1 1 AAA domain AAA_2 PF07724.14 EKX38208.1 - 0.014 15.5 0.0 0.11 12.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 EKX38208.1 - 0.024 15.2 0.0 0.091 13.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EKX38208.1 - 0.031 13.5 0.0 0.088 12.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 EKX38208.1 - 0.031 14.4 0.0 0.067 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EKX38208.1 - 0.04 13.6 0.2 0.54 9.9 0.0 2.6 2 1 0 3 3 3 0 Sigma-54 interaction domain AAA_28 PF13521.6 EKX38208.1 - 0.042 14.1 0.0 0.092 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EKX38208.1 - 0.055 13.9 0.3 0.19 12.2 0.0 2.1 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 EKX38208.1 - 0.064 13.3 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 EKX38208.1 - 0.065 12.6 0.1 0.65 9.3 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_14 PF13173.6 EKX38208.1 - 0.07 13.2 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EKX38208.1 - 0.073 12.6 0.7 0.32 10.5 0.3 2.3 2 1 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 EKX38208.1 - 0.11 13.0 0.8 0.51 10.9 0.8 2.1 1 0 0 1 1 1 0 ABC transporter Parvo_NS1 PF01057.17 EKX38208.1 - 0.12 11.4 0.1 0.43 9.6 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 EKX38208.1 - 0.15 12.0 1.1 1.4 8.8 0.2 2.7 3 0 0 3 3 3 0 NACHT domain AAA_23 PF13476.6 EKX38209.1 - 8.1e-11 42.8 0.1 1.6e-10 41.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EKX38209.1 - 0.0015 18.0 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 EKX38209.1 - 0.068 13.7 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter GTSE1_N PF15259.6 EKX38210.1 - 0.33 11.1 6.2 0.77 9.9 6.2 1.8 1 1 0 1 1 1 0 G-2 and S-phase expressed 1 DUF4286 PF14114.6 EKX38210.1 - 1.3 9.6 10.8 6.9 7.2 1.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4286) Spore_III_AB PF09548.10 EKX38210.1 - 2.7 8.1 10.5 0.18 11.9 3.9 2.1 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) LRR_8 PF13855.6 EKX38211.1 - 3.1e-34 116.5 42.1 3.4e-12 46.0 5.2 5.6 3 2 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 EKX38211.1 - 2.6e-27 94.4 43.5 1.9e-07 31.3 1.9 6.5 6 1 0 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX38211.1 - 0.049 14.2 48.3 30 5.7 0.0 11.1 9 3 0 9 9 9 0 Leucine Rich Repeat LRR_6 PF13516.6 EKX38211.1 - 0.39 10.9 34.8 7.9 6.8 0.1 9.1 9 0 0 9 9 9 0 Leucine Rich repeat CREPT PF16566.5 EKX38211.1 - 2.9 8.1 6.7 7.3 6.8 0.2 4.1 2 2 2 4 4 4 0 Cell-cycle alteration and expression-elevated protein in tumour PI_PP_I PF18363.1 EKX38212.1 - 2.9 8.1 15.3 0.36 11.1 1.1 4.1 4 0 0 4 4 4 0 Phosphoinositide phosphatase insertion domain MORN PF02493.20 EKX38215.1 - 5.9e-11 41.6 3.9 9.8e-07 28.3 0.3 3.5 3 0 0 3 3 3 2 MORN repeat Flavodoxin_4 PF12682.7 EKX38215.1 - 0.0063 16.2 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin TRP PF06011.12 EKX38215.1 - 0.23 10.2 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel LRR_8 PF13855.6 EKX38218.1 - 4e-30 103.4 57.1 2.3e-07 30.4 4.8 6.8 4 3 3 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 EKX38218.1 - 2e-24 85.2 56.9 1.8e-07 31.4 1.9 8.2 5 2 3 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX38218.1 - 0.00044 20.4 47.8 1.2 10.0 0.7 11.1 10 2 0 10 10 10 3 Leucine Rich Repeat DUF5519 PF17648.1 EKX38218.1 - 0.0073 16.2 3.1 2.2 8.2 0.0 3.2 3 0 0 3 3 3 2 Family of unknown function (DUF5519) LRR_2 PF07723.13 EKX38218.1 - 0.0087 16.7 5.1 7.7 7.4 0.1 5.7 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.6 EKX38218.1 - 0.017 15.1 42.2 1.3 9.3 0.2 9.8 10 0 0 10 10 10 0 Leucine Rich repeat RPN6_C_helix PF18503.1 EKX38219.1 - 1.3e-05 24.8 0.6 38 4.1 0.0 7.4 10 0 0 10 10 10 0 26S proteasome subunit RPN6 C-terminal helix domain TMEM125 PF15109.6 EKX38219.1 - 0.031 14.6 3.9 0.45 10.9 0.2 3.0 1 1 2 3 3 3 0 TMEM125 protein family Phage_Treg PF04761.12 EKX38219.1 - 0.11 12.6 6.7 2.2e+02 2.0 0.1 6.9 6 3 4 10 10 10 0 Lactococcus bacteriophage putative transcription regulator Pox_I3 PF04661.12 EKX38219.1 - 0.12 11.4 0.9 0.22 10.6 0.9 1.4 1 0 0 1 1 1 0 Poxvirus I3 ssDNA-binding protein EHD_N PF16880.5 EKX38219.1 - 0.13 12.2 0.0 30 4.6 0.0 4.1 3 1 2 5 5 5 0 N-terminal EH-domain containing protein Ion_trans PF00520.31 EKX38220.1 - 2.7e-13 49.7 0.6 3.3e-13 49.5 0.6 1.1 1 0 0 1 1 1 1 Ion transport protein Methyltransf_16 PF10294.9 EKX38221.1 - 1.2e-18 67.5 0.1 2.5e-18 66.4 0.1 1.5 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EKX38221.1 - 4.5e-05 23.3 0.0 6.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EKX38221.1 - 0.0012 18.3 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 EKX38221.1 - 0.003 18.3 0.2 0.008 16.9 0.2 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX38221.1 - 0.01 16.5 0.4 0.027 15.2 0.4 1.7 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EKX38221.1 - 0.033 13.9 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EKX38221.1 - 0.038 13.6 0.1 0.076 12.6 0.1 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_11 PF08241.12 EKX38221.1 - 0.12 13.0 0.1 0.22 12.2 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Abhydrolase_3 PF07859.13 EKX38221.1 - 0.16 11.8 0.1 0.4 10.5 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Glyco_transf_17 PF04724.13 EKX38222.1 - 5.1e-26 91.5 0.0 1.4e-17 63.8 0.0 2.8 2 1 1 3 3 3 2 Glycosyltransferase family 17 Vasohibin PF14822.6 EKX38224.1 - 0.00029 20.2 0.0 0.00059 19.1 0.0 1.4 1 1 0 1 1 1 1 Vasohibin ZapB PF06005.12 EKX38225.1 - 9.5e-07 29.2 4.6 2.5e-06 27.8 4.6 1.6 1 0 0 1 1 1 1 Cell division protein ZapB Baculo_PEP_C PF04513.12 EKX38225.1 - 0.0035 17.4 4.2 0.082 12.9 3.6 2.2 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin PF02996.17 EKX38225.1 - 0.0039 17.1 1.3 0.15 12.0 0.1 2.5 1 1 1 2 2 2 1 Prefoldin subunit Myosin_tail_1 PF01576.19 EKX38225.1 - 0.023 12.6 1.5 0.029 12.2 1.5 1.0 1 0 0 1 1 1 0 Myosin tail CENP-F_leu_zip PF10473.9 EKX38225.1 - 0.029 14.4 6.4 0.067 13.2 6.2 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 EKX38225.1 - 0.03 13.2 4.5 0.05 12.5 4.5 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein TMPIT PF07851.13 EKX38225.1 - 0.03 13.6 1.8 0.041 13.1 1.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein Prefoldin_2 PF01920.20 EKX38225.1 - 0.034 14.1 3.6 0.85 9.6 0.2 2.5 1 1 1 2 2 2 0 Prefoldin subunit DUF4795 PF16043.5 EKX38225.1 - 0.056 13.1 3.6 0.088 12.4 3.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) ApoLp-III PF07464.11 EKX38225.1 - 0.062 13.4 2.9 0.13 12.3 2.9 1.5 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) CLZ PF16526.5 EKX38225.1 - 0.073 13.4 1.7 0.24 11.8 0.7 2.2 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels EzrA PF06160.12 EKX38225.1 - 0.074 11.2 0.7 0.1 10.7 0.7 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA YvrJ PF12841.7 EKX38225.1 - 0.083 12.4 0.4 0.083 12.4 0.4 2.0 3 0 0 3 3 2 0 YvrJ protein family JIP_LZII PF16471.5 EKX38225.1 - 0.12 12.5 4.0 0.28 11.4 0.2 2.5 2 1 1 3 3 2 0 JNK-interacting protein leucine zipper II WEMBL PF05701.11 EKX38225.1 - 0.13 11.0 3.9 0.17 10.6 3.9 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light HAUS-augmin3 PF14932.6 EKX38225.1 - 0.13 11.8 5.0 0.2 11.2 5.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF948 PF06103.11 EKX38225.1 - 0.14 12.4 0.9 0.73 10.1 0.8 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Tup_N PF08581.10 EKX38225.1 - 0.16 12.3 1.3 0.34 11.3 0.8 1.8 2 1 0 2 2 1 0 Tup N-terminal DUF5082 PF16888.5 EKX38225.1 - 0.22 11.8 6.0 1.3 9.3 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) SlyX PF04102.12 EKX38225.1 - 0.24 12.0 3.2 0.62 10.7 3.2 1.6 1 0 0 1 1 1 0 SlyX DUF2408 PF10303.9 EKX38225.1 - 0.39 11.3 3.3 0.63 10.6 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF1664 PF07889.12 EKX38225.1 - 0.42 10.7 4.5 0.86 9.7 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Nup54 PF13874.6 EKX38225.1 - 0.53 10.4 4.4 1.1 9.3 4.4 1.5 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 FlaC_arch PF05377.11 EKX38225.1 - 0.7 10.3 5.1 0.51 10.8 0.4 2.6 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Spc24 PF08286.11 EKX38225.1 - 1.4 9.2 5.3 4.4 7.6 3.8 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Syntaxin-6_N PF09177.11 EKX38225.1 - 1.5 9.4 5.7 10 6.8 1.4 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal GIT_CC PF16559.5 EKX38225.1 - 7.5 6.5 9.4 16 5.4 1.4 2.9 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor ZapB PF06005.12 EKX38226.1 - 1.3e-06 28.8 4.6 3.3e-06 27.5 4.6 1.6 1 0 0 1 1 1 1 Cell division protein ZapB Baculo_PEP_C PF04513.12 EKX38226.1 - 0.0067 16.5 4.4 0.11 12.6 4.4 2.1 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin PF02996.17 EKX38226.1 - 0.0072 16.2 1.5 0.19 11.7 0.1 2.5 1 1 1 2 2 2 1 Prefoldin subunit Myosin_tail_1 PF01576.19 EKX38226.1 - 0.031 12.1 1.5 0.04 11.7 1.5 1.0 1 0 0 1 1 1 0 Myosin tail CENP-F_leu_zip PF10473.9 EKX38226.1 - 0.032 14.2 6.0 0.069 13.2 5.8 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 EKX38226.1 - 0.037 12.9 4.3 0.06 12.2 4.3 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein TMPIT PF07851.13 EKX38226.1 - 0.038 13.3 1.8 0.057 12.7 1.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein Prefoldin_2 PF01920.20 EKX38226.1 - 0.04 13.9 3.2 1.1 9.3 0.1 2.6 1 1 1 2 2 2 0 Prefoldin subunit DUF4795 PF16043.5 EKX38226.1 - 0.045 13.3 2.8 0.08 12.5 2.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) YvrJ PF12841.7 EKX38226.1 - 0.065 12.8 1.7 0.1 12.1 0.4 2.0 2 0 0 2 2 2 0 YvrJ protein family ApoLp-III PF07464.11 EKX38226.1 - 0.09 12.9 3.1 0.21 11.7 3.0 1.6 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) EzrA PF06160.12 EKX38226.1 - 0.096 10.8 0.7 0.14 10.3 0.7 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA CLZ PF16526.5 EKX38226.1 - 0.1 13.0 1.5 0.27 11.6 0.4 2.1 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Tup_N PF08581.10 EKX38226.1 - 0.16 12.3 0.9 0.41 11.0 0.8 1.7 2 0 0 2 2 1 0 Tup N-terminal WEMBL PF05701.11 EKX38226.1 - 0.17 10.6 3.8 0.22 10.1 3.8 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF5082 PF16888.5 EKX38226.1 - 0.31 11.3 5.8 1.7 9.0 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) JIP_LZII PF16471.5 EKX38226.1 - 0.32 11.2 4.7 0.36 11.0 0.2 2.4 2 1 1 3 3 2 0 JNK-interacting protein leucine zipper II SlyX PF04102.12 EKX38226.1 - 0.33 11.6 3.2 0.82 10.3 3.2 1.6 1 0 0 1 1 1 0 SlyX DUF1664 PF07889.12 EKX38226.1 - 0.56 10.3 4.3 1.1 9.3 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Nup54 PF13874.6 EKX38226.1 - 0.79 9.8 4.5 1.7 8.8 4.5 1.5 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 FlaC_arch PF05377.11 EKX38226.1 - 0.84 10.1 4.7 0.63 10.5 0.4 2.6 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Spc24 PF08286.11 EKX38226.1 - 1.6 9.0 4.9 3.1 8.1 2.9 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Syntaxin-6_N PF09177.11 EKX38226.1 - 2 9.1 5.5 1.3e+02 3.2 5.5 2.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Ribonuc_red_lgC PF02867.15 EKX38227.1 - 1.8e-178 594.4 0.0 2.3e-178 594.0 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EKX38227.1 - 1.2e-23 82.9 0.0 4.2e-23 81.2 0.0 2.0 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EKX38227.1 - 3.2e-14 53.2 0.1 7.7e-14 52.0 0.1 1.7 1 0 0 1 1 1 1 ATP cone domain CAP_C PF08603.11 EKX38228.1 - 7.1e-20 71.2 7.2 1.5e-19 70.2 7.2 1.5 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal BIR PF00653.21 EKX38228.1 - 1.5e-19 70.4 0.1 1.5e-19 70.4 0.1 1.7 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain TBCC PF07986.12 EKX38228.1 - 6.2e-06 26.0 3.9 3.2e-05 23.6 5.0 1.6 2 0 0 2 2 2 1 Tubulin binding cofactor C zf-C3HC PF07967.13 EKX38228.1 - 0.0056 16.7 0.1 0.049 13.7 0.0 2.1 2 0 0 2 2 2 1 C3HC zinc finger-like SPRY PF00622.28 EKX38230.1 - 1.8e-33 115.2 0.0 4.4e-10 39.7 0.0 3.5 3 0 0 3 3 3 3 SPRY domain Phage-tail_3 PF13550.6 EKX38230.1 - 0.00073 19.4 0.2 26 4.6 0.0 4.1 4 0 0 4 4 4 3 Putative phage tail protein DUF2635 PF10948.8 EKX38230.1 - 0.0015 18.2 0.0 28 4.5 0.0 3.5 3 0 0 3 3 3 3 Protein of unknown function (DUF2635) NUDIX PF00293.28 EKX38231.1 - 3e-14 53.2 0.0 4.8e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-Di19 PF05605.12 EKX38231.1 - 0.00072 19.8 1.8 0.0016 18.7 1.8 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding DUF4212 PF13937.6 EKX38232.1 - 0.0098 16.3 0.7 0.0098 16.3 0.7 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF4212) TMEM43 PF07787.12 EKX38232.1 - 0.24 10.8 1.5 0.53 9.6 1.5 1.6 1 0 0 1 1 1 0 Transmembrane protein 43 XPG_N PF00752.17 EKX38233.1 - 2.8e-29 101.6 0.1 3.5e-29 101.2 0.1 1.1 1 0 0 1 1 1 1 XPG N-terminal domain HTH_8 PF02954.19 EKX38233.1 - 0.018 14.8 0.0 0.068 13.0 0.0 1.9 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family XRN_N PF03159.18 EKX38233.1 - 0.13 11.6 0.8 0.19 11.1 0.8 1.3 1 1 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus NICE-3 PF07406.11 EKX38235.1 - 0.0013 18.7 0.0 0.002 18.2 0.0 1.2 1 0 0 1 1 1 1 NICE-3 protein DUF4473 PF14747.6 EKX38235.1 - 0.073 13.6 0.2 0.11 13.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) PLAC8 PF04749.17 EKX38238.1 - 1.1e-16 61.6 26.7 2.6e-09 38.0 18.4 2.3 1 1 1 2 2 2 2 PLAC8 family SAPS PF04499.15 EKX38238.1 - 0.086 11.6 0.7 0.11 11.3 0.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein AIF_C PF14721.6 EKX38238.1 - 0.096 13.0 7.2 0.34 11.3 7.2 1.9 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term dsRBD2 PF17842.1 EKX38238.1 - 0.56 10.4 6.0 0.19 11.9 1.5 2.5 3 0 0 3 3 3 0 Double-stranded RNA binding domain 2 Glyco_hydro_18 PF00704.28 EKX38239.1 - 7.2e-11 42.4 0.0 7.8e-11 42.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Mfa1 PF17445.2 EKX38239.1 - 0.29 11.2 2.7 0.54 10.3 2.7 1.4 1 1 0 1 1 1 0 Mating factor A1 CS PF04969.16 EKX38240.1 - 0.078 14.0 0.1 0.2 12.7 0.1 1.7 1 0 0 1 1 1 0 CS domain Sporozoite_P67 PF05642.11 EKX38241.1 - 7.2 4.6 18.9 0.42 8.6 13.0 1.7 2 0 0 2 2 2 0 Sporozoite P67 surface antigen SR-25 PF10500.9 EKX38241.1 - 8.4 5.9 10.5 17 4.9 10.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3228 PF11539.8 EKX38242.1 - 0.015 14.8 0.1 0.023 14.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3228) DUF469 PF04320.14 EKX38242.1 - 0.1 13.5 0.2 5.7 7.9 0.0 2.7 1 1 2 3 3 3 0 Protein with unknown function (DUF469) Arm PF00514.23 EKX38243.1 - 0.087 12.9 4.0 35 4.6 1.0 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EKX38243.1 - 0.3 11.1 2.1 0.79 9.8 0.1 2.1 1 1 1 2 2 2 0 Spinocerebellar ataxia type 10 protein domain DEAD PF00270.29 EKX38245.1 - 4e-45 153.7 0.0 7.5e-45 152.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX38245.1 - 1.1e-26 93.3 0.1 2.9e-26 92.0 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX38245.1 - 2.6e-07 30.8 0.0 5.2e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EKX38245.1 - 1.1e-05 24.8 0.0 1.7e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Corona_NS4 PF03905.13 EKX38245.1 - 0.0081 16.1 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 Coronavirus non-structural protein NS4 CMS1 PF14617.6 EKX38245.1 - 0.016 14.6 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Hemerythrin PF01814.23 EKX38246.1 - 1.3e-06 29.1 4.7 0.0048 17.5 0.4 2.2 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain DUF3150 PF11348.8 EKX38246.1 - 0.0022 17.3 0.2 0.0033 16.7 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3150) Methyltransf_31 PF13847.6 EKX38248.1 - 7.2e-09 35.6 0.0 1.7e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EKX38248.1 - 2.7e-06 27.0 0.0 5.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EKX38248.1 - 3.1e-06 27.8 0.0 1.6e-05 25.5 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 EKX38248.1 - 9e-06 24.9 8.8 0.0013 17.8 1.6 3.1 2 1 0 2 2 2 2 tRNA (Uracil-5-)-methyltransferase PrmA PF06325.13 EKX38248.1 - 0.00038 20.0 0.0 0.00067 19.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 EKX38248.1 - 0.00066 19.4 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_32 PF13679.6 EKX38248.1 - 0.0031 17.5 9.5 0.015 15.3 0.1 3.4 3 1 1 4 4 4 2 Methyltransferase domain Methyltransf_4 PF02390.17 EKX38248.1 - 0.0035 16.8 0.1 0.0066 15.9 0.1 1.4 1 0 0 1 1 1 1 Putative methyltransferase UPF0020 PF01170.18 EKX38248.1 - 0.0052 16.5 0.5 0.035 13.8 0.3 2.3 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 EKX38248.1 - 0.0056 16.0 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_11 PF08241.12 EKX38248.1 - 0.01 16.5 0.0 0.059 14.0 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Macoilin PF09726.9 EKX38249.1 - 1.7 7.1 7.2 2 6.9 7.2 1.1 1 0 0 1 1 1 0 Macoilin family DUF2800 PF10926.8 EKX38250.1 - 0.16 11.2 0.1 0.16 11.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) Ribonuclease_P PF00825.18 EKX38251.1 - 0.12 12.5 0.1 0.12 12.5 0.1 1.8 2 0 0 2 2 2 0 Ribonuclease P Spc7 PF08317.11 EKX38252.1 - 0.0015 17.5 2.9 0.0017 17.3 2.5 1.3 1 1 0 1 1 1 1 Spc7 kinetochore protein RWP-RK PF02042.15 EKX38254.1 - 7.4e-12 45.1 0.1 1.1e-11 44.5 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX38255.1 - 5.8e-12 45.4 0.1 8.5e-12 44.9 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX38256.1 - 5.8e-12 45.4 0.1 8.5e-12 44.9 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain Helicase_C PF00271.31 EKX38257.1 - 1.2e-13 51.3 0.0 2.5e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 EKX38257.1 - 2.8e-06 27.1 14.9 4.4e-06 26.5 14.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX38257.1 - 6.2e-05 23.2 13.9 0.0001 22.6 13.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EKX38257.1 - 0.00013 21.8 12.7 0.00021 21.1 12.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX38257.1 - 0.00058 19.7 12.8 0.0011 18.8 12.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EKX38257.1 - 0.00062 19.5 13.9 0.0014 18.5 13.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SNF2_N PF00176.23 EKX38257.1 - 0.00088 18.1 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_UBOX PF13445.6 EKX38257.1 - 0.002 18.1 7.8 0.0055 16.7 7.7 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 EKX38257.1 - 0.0049 17.1 8.0 0.0088 16.3 8.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EKX38257.1 - 0.017 15.1 13.4 0.034 14.1 13.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 EKX38257.1 - 0.052 13.6 5.5 0.11 12.5 5.5 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EKX38257.1 - 0.68 10.1 15.2 1.3 9.3 15.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Arf PF00025.21 EKX38258.1 - 2.3e-51 173.7 0.0 2.7e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EKX38258.1 - 1.1e-12 47.8 0.0 1.3e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EKX38258.1 - 2.4e-12 47.1 0.0 3.1e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EKX38258.1 - 3.4e-12 46.2 4.3 2.4e-07 30.3 2.3 2.8 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 EKX38258.1 - 3e-08 33.7 0.0 4e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EKX38258.1 - 2.3e-07 30.4 0.0 2.7e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EKX38258.1 - 2e-05 24.1 0.1 2.4e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EKX38258.1 - 0.00024 20.7 0.0 0.0016 18.0 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EKX38258.1 - 0.015 15.6 0.0 0.035 14.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 EKX38258.1 - 0.06 12.9 0.1 0.098 12.2 0.1 1.5 1 1 0 1 1 1 0 Ferrous iron transport protein B SAM_PNT PF02198.16 EKX38258.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Dynamin_N PF00350.23 EKX38258.1 - 0.16 12.0 0.1 15 5.6 0.0 2.1 1 1 1 2 2 2 0 Dynamin family bZIP_1 PF00170.21 EKX38259.1 - 0.011 15.8 2.3 0.011 15.8 2.3 7.2 6 1 2 8 8 8 0 bZIP transcription factor DUF4806 PF16064.5 EKX38259.1 - 0.8 10.0 6.2 7.2 7.0 1.0 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4806) DUF1633 PF07794.11 EKX38259.1 - 2.4 6.2 11.4 0.13 10.4 5.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1633) LPP PF04728.13 EKX38259.1 - 3.5 8.1 12.0 26 5.3 0.2 4.8 4 0 0 4 4 4 0 Lipoprotein leucine-zipper p450 PF00067.22 EKX38260.1 - 2.3e-29 102.5 0.1 7.4e-10 38.2 0.0 3.7 2 1 1 3 3 3 3 Cytochrome P450 DUF4215 PF13948.6 EKX38261.1 - 4.9e-18 65.3 18.5 3.7e-11 43.3 8.5 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4215) Nas2_N PF18265.1 EKX38263.1 - 6.5e-29 99.7 0.1 9.8e-29 99.1 0.1 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 EKX38263.1 - 4.5e-09 36.0 0.9 1.2e-08 34.7 0.9 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX38263.1 - 7.5e-09 35.8 0.0 1.2e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 EKX38263.1 - 1.8e-05 25.1 0.0 3.9e-05 24.0 0.0 1.5 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 EKX38263.1 - 2.3e-05 24.6 0.0 4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain MycE_N PF17843.1 EKX38264.1 - 0.041 14.4 0.3 0.088 13.3 0.3 1.5 1 0 0 1 1 1 0 MycE methyltransferase N-terminal Cyclophil_like PF04126.13 EKX38264.1 - 0.048 13.5 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 Cyclophilin-like TetR_C_7 PF14246.6 EKX38264.1 - 0.11 12.6 0.1 0.18 11.8 0.1 1.4 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain DUF1981 PF09324.10 EKX38265.1 - 8.4e-14 51.2 9.7 3.9e-11 42.7 0.4 5.5 5 0 0 5 5 5 2 Domain of unknown function (DUF1981) DCB PF16213.5 EKX38265.1 - 1.2e-08 34.8 1.0 1.2e-08 34.8 1.0 4.3 5 0 0 5 5 5 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 EKX38265.1 - 1.2e-05 25.3 0.7 1.2e-05 25.3 0.7 4.8 4 1 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal TFCD_C PF12612.8 EKX38265.1 - 0.014 15.3 0.2 0.12 12.1 0.0 2.7 2 0 0 2 2 2 0 Tubulin folding cofactor D C terminal HEAT PF02985.22 EKX38265.1 - 0.024 14.9 1.0 15 6.2 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat DnaJ PF00226.31 EKX38266.1 - 9.1e-14 51.3 0.0 1.5e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain TT_ORF1 PF02956.14 EKX38266.1 - 0.025 13.3 20.8 0.03 13.0 20.8 1.2 1 0 0 1 1 1 0 TT viral orf 1 HMG_box PF00505.19 EKX38267.1 - 2.5e-20 72.6 0.3 3.5e-20 72.2 0.3 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EKX38267.1 - 1.9e-10 41.1 0.0 3.1e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 EKX38267.1 - 0.031 14.2 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain Peptidase_M16_M PF16187.5 EKX38271.1 - 2.4e-64 217.4 0.0 6.1e-64 216.0 0.0 1.7 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EKX38271.1 - 5.9e-43 146.4 0.8 9.1e-43 145.8 0.1 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EKX38271.1 - 1e-27 97.3 0.1 1.7e-17 64.1 0.0 3.6 4 1 1 5 5 5 2 Peptidase M16 inactive domain PRIMA1 PF16101.5 EKX38271.1 - 0.047 13.7 11.9 0.14 12.2 11.9 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 EKX38271.1 - 0.17 11.9 9.1 0.36 10.9 9.1 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EKX38271.1 - 0.38 10.2 11.2 1.7 8.1 11.5 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal zf-C2H2_2 PF12756.7 EKX38272.1 - 2.7e-21 75.8 1.3 2.8e-21 75.7 1.3 1.0 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 EKX38272.1 - 0.00033 20.9 0.4 0.00073 19.8 0.4 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EKX38272.1 - 0.00081 19.6 1.5 0.0021 18.3 0.2 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EKX38272.1 - 0.0048 17.6 0.7 0.013 16.3 0.1 2.1 1 1 1 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 EKX38272.1 - 0.0048 17.3 0.5 0.012 16.1 0.2 1.9 1 1 0 1 1 1 1 Zinc finger, C2H2 type HET PF06985.11 EKX38273.1 - 0.0011 19.3 0.6 0.07 13.5 0.0 2.5 1 1 0 2 2 2 2 Heterokaryon incompatibility protein (HET) APH PF01636.23 EKX38274.1 - 7.6e-25 88.2 0.0 1e-24 87.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EKX38274.1 - 3.9e-09 36.4 0.4 2e-07 30.9 0.2 2.2 2 0 0 2 2 2 2 Choline/ethanolamine kinase CIA30 PF08547.12 EKX38274.1 - 0.12 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) SpoIIIAH PF12685.7 EKX38275.1 - 0.00026 20.9 11.6 0.0003 20.7 11.6 1.2 1 0 0 1 1 1 1 SpoIIIAH-like protein CDC27 PF09507.10 EKX38275.1 - 0.22 10.9 32.4 0.3 10.4 32.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Mitofilin PF09731.9 EKX38275.1 - 0.34 9.7 28.6 0.38 9.5 28.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Hamartin PF04388.12 EKX38275.1 - 0.41 9.3 3.6 0.41 9.2 3.6 1.1 1 0 0 1 1 1 0 Hamartin protein DUF966 PF06136.13 EKX38275.1 - 1.2 8.8 7.3 1.3 8.7 7.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SAPS PF04499.15 EKX38275.1 - 1.2 7.8 6.1 1.2 7.8 6.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ADIP PF11559.8 EKX38275.1 - 6.2 6.9 17.9 8.7 6.4 17.9 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding SWI-SNF_Ssr4 PF08549.10 EKX38275.1 - 7.9 5.0 18.0 10 4.6 18.0 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) ARS2 PF04959.13 EKX38276.1 - 0.12 12.7 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 Arsenite-resistance protein 2 HTH_Tnp_Tc5 PF03221.16 EKX38278.1 - 1.2e-06 28.4 0.1 1.9e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 EKX38278.1 - 0.0011 18.6 0.0 0.0031 17.1 0.0 1.8 1 1 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_3 PF01381.22 EKX38278.1 - 0.012 15.7 0.1 0.083 13.0 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix HTH_38 PF13936.6 EKX38278.1 - 0.026 14.3 2.3 0.27 11.0 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 EKX38278.1 - 0.054 13.3 0.9 0.4 10.5 0.0 2.7 3 1 0 3 3 3 0 Homeodomain-like domain MarR_2 PF12802.7 EKX38278.1 - 0.079 12.9 0.1 0.36 10.8 0.0 2.1 2 1 0 2 2 2 0 MarR family Sigma70_r4 PF04545.16 EKX38278.1 - 0.1 12.1 1.3 0.53 9.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 COMM_domain PF07258.14 EKX38279.1 - 5.1e-15 55.4 1.1 7e-15 54.9 0.4 1.6 2 0 0 2 2 2 1 COMM domain Herpes_pp85 PF04637.12 EKX38279.1 - 0.02 13.3 1.7 0.035 12.5 1.2 1.5 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) TB2_DP1_HVA22 PF03134.19 EKX38280.1 - 5.9e-26 90.2 4.4 5.9e-26 90.2 4.4 2.1 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Lig_chan PF00060.26 EKX38280.1 - 0.00074 19.4 0.6 0.001 18.9 0.6 1.2 1 0 0 1 1 1 1 Ligand-gated ion channel FA_desaturase PF00487.24 EKX38280.1 - 0.097 12.5 0.3 0.1 12.4 0.3 1.1 1 0 0 1 1 1 0 Fatty acid desaturase ESAG1 PF03238.13 EKX38280.1 - 0.099 12.1 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 ESAG protein CNDH2_N PF06278.11 EKX38280.1 - 0.26 11.5 3.6 0.22 11.7 1.8 1.7 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Hep_59 PF07052.11 EKX38281.1 - 1.4e-16 61.2 1.7 1.4e-16 61.2 1.7 2.2 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 DUF1997 PF09366.10 EKX38282.1 - 1.8e-13 50.9 0.0 1.8e-12 47.7 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1997) Pkinase PF00069.25 EKX38283.1 - 9.5e-07 28.4 0.0 2.7e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EKX38283.1 - 0.026 13.9 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Gp_dh_C PF02800.20 EKX38285.1 - 9.2e-54 181.3 0.1 9.2e-54 181.3 0.1 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EKX38285.1 - 2.3e-32 111.4 1.4 8.4e-32 109.5 0.0 2.5 3 1 0 3 3 3 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain MFS_1 PF07690.16 EKX38286.1 - 3.9e-08 32.6 21.9 6.6e-07 28.6 8.1 3.1 3 0 0 3 3 3 2 Major Facilitator Superfamily Yae1_N PF09811.9 EKX38286.1 - 0.57 9.9 5.9 1.4 8.7 5.9 1.7 1 0 0 1 1 1 0 Essential protein Yae1, N terminal zf-FLZ PF04570.14 EKX38287.1 - 0.021 14.3 1.2 0.021 14.3 1.2 2.3 2 0 0 2 2 2 0 zinc-finger of the FCS-type, C2-C2 Pkinase PF00069.25 EKX38288.1 - 2.1e-63 214.2 0.0 2.3e-63 214.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX38288.1 - 1.7e-33 116.0 0.0 1.9e-33 115.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX38288.1 - 7.1e-08 32.1 0.0 1.6e-07 30.9 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EKX38288.1 - 0.00047 19.6 0.0 0.00074 18.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EKX38288.1 - 0.011 14.5 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 EKX38288.1 - 0.015 14.3 0.0 0.019 14.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RAMP4 PF06624.12 EKX38288.1 - 0.051 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 Seadorna_VP7 PF07387.11 EKX38288.1 - 0.096 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 EKX38288.1 - 0.17 10.8 0.0 0.25 10.3 0.0 1.3 1 1 0 1 1 1 0 Haspin like kinase domain Spt5_N PF11942.8 EKX38289.1 - 0.67 11.0 2.8 0.88 10.6 2.8 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal AhpC-TSA PF00578.21 EKX38290.1 - 9.1e-37 125.7 0.0 1.2e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EKX38290.1 - 8.1e-15 54.8 0.0 9.8e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EKX38290.1 - 1.2e-06 28.2 0.1 2.3e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 EKX38290.1 - 0.063 13.2 0.0 0.15 12.0 0.0 1.5 2 0 0 2 2 2 0 SCO1/SenC Biotin_carb_C PF02785.19 EKX38291.1 - 5.1e-06 26.5 0.6 0.42 10.7 0.0 3.8 1 1 2 3 3 3 3 Biotin carboxylase C-terminal domain PNPase PF03726.14 EKX38291.1 - 0.035 14.6 3.9 7.1 7.2 0.0 2.7 1 1 1 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF4678 PF15727.5 EKX38291.1 - 0.048 12.9 0.0 3.9 6.6 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4678) 4HB_MCP_1 PF12729.7 EKX38291.1 - 0.058 12.9 2.1 0.17 11.4 1.2 2.0 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction Methyltransf_20 PF12147.8 EKX38291.1 - 0.067 12.3 1.4 0.1 11.7 1.4 1.3 1 0 0 1 1 1 0 Putative methyltransferase Tim44 PF04280.15 EKX38291.1 - 0.072 13.2 2.3 0.11 12.6 2.3 1.4 1 0 0 1 1 1 0 Tim44-like domain Collagen_mid PF15984.5 EKX38291.1 - 0.16 11.7 0.0 1.1 9.0 0.0 2.0 1 1 1 2 2 2 0 Bacterial collagen, middle region Herpes_IE2_3 PF03361.14 EKX38291.1 - 0.21 11.5 1.4 0.56 10.1 0.3 2.2 1 1 1 2 2 2 0 Herpes virus intermediate/early protein 2/3 Grg1 PF11034.8 EKX38291.1 - 1.6 9.0 7.7 4.2 7.7 1.6 3.1 2 1 2 4 4 4 0 Glucose-repressible protein Grg1 V_ATPase_I PF01496.19 EKX38292.1 - 0.015 13.2 0.1 1.2 7.0 0.2 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family NicO PF03824.16 EKX38292.1 - 0.018 14.4 5.1 0.024 14.0 0.4 2.2 2 0 0 2 2 2 0 High-affinity nickel-transport protein GlutR_N PF05201.15 EKX38294.1 - 3.9e-42 143.5 0.4 6.7e-42 142.7 0.4 1.4 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 EKX38294.1 - 2.2e-32 112.0 0.2 4.4e-32 111.0 0.2 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 EKX38294.1 - 2.2e-24 85.7 0.3 7.7e-24 84.0 0.3 1.9 2 0 0 2 2 2 1 Glutamyl-tRNAGlu reductase, dimerisation domain OCD_Mu_crystall PF02423.15 EKX38294.1 - 2.1e-05 23.7 0.0 6e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.17 EKX38294.1 - 0.00031 21.3 0.0 0.0011 19.5 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 EKX38294.1 - 0.0056 16.9 0.1 0.033 14.4 0.0 2.5 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EKX38294.1 - 0.065 13.5 0.0 0.27 11.5 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain GlutR_N PF05201.15 EKX38295.1 - 2.5e-42 144.1 0.4 4.2e-42 143.4 0.4 1.4 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain Shikimate_DH PF01488.20 EKX38295.1 - 2e-32 112.1 0.2 5.1e-32 110.8 0.2 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GlutR_dimer PF00745.20 EKX38295.1 - 1.1e-23 83.5 0.8 3.8e-23 81.8 0.8 1.9 2 0 0 2 2 2 1 Glutamyl-tRNAGlu reductase, dimerisation domain OCD_Mu_crystall PF02423.15 EKX38295.1 - 2.7e-05 23.3 0.2 6.8e-05 21.9 0.0 1.7 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.17 EKX38295.1 - 0.00035 21.1 0.0 0.0013 19.3 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 EKX38295.1 - 0.066 13.7 0.3 2.3 8.7 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding TrkA_N PF02254.18 EKX38295.1 - 0.067 13.5 0.0 0.3 11.4 0.0 2.1 2 0 0 2 2 2 0 TrkA-N domain Ion_trans PF00520.31 EKX38296.1 - 1.1e-25 90.3 6.1 1.6e-25 89.8 6.1 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX38296.1 - 7.8e-10 38.6 5.0 7.8e-10 38.6 5.0 2.3 3 1 0 3 3 3 1 Ion channel cNMP_binding PF00027.29 EKX38296.1 - 0.0016 18.5 0.0 0.076 13.1 0.0 2.7 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain HELP PF03451.14 EKX38297.1 - 3.1e-13 49.4 0.6 2.9e-12 46.3 0.0 2.6 2 0 0 2 2 2 1 HELP motif WD40 PF00400.32 EKX38297.1 - 9.6e-08 32.6 9.7 0.07 14.0 0.0 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat RLL PF10036.9 EKX38299.1 - 1.2e-33 117.1 0.2 1.8e-33 116.5 0.2 1.1 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein UPF0158 PF03682.13 EKX38299.1 - 0.43 10.5 1.8 13 5.7 0.1 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0158) REV PF00424.18 EKX38301.1 - 0.0018 18.2 0.7 0.004 17.2 0.7 1.6 1 0 0 1 1 1 1 REV protein (anti-repression trans-activator protein) Beta_helix PF13229.6 EKX38301.1 - 0.0049 16.7 0.1 0.017 15.0 0.1 1.8 1 1 0 1 1 1 1 Right handed beta helix region Sigma70_ner PF04546.13 EKX38301.1 - 0.022 14.6 5.2 0.039 13.8 2.0 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Dishevelled PF02377.15 EKX38301.1 - 0.42 11.1 8.5 0.025 15.0 3.3 1.6 2 0 0 2 2 2 0 Dishevelled specific domain Phytochelatin PF05023.14 EKX38302.1 - 5.2e-19 68.3 0.2 2.5e-17 62.8 0.0 2.2 2 0 0 2 2 2 2 Phytochelatin synthase Nbl1_Borealin_N PF10444.9 EKX38304.1 - 0.37 10.5 7.5 0.088 12.5 2.4 2.6 4 0 0 4 4 4 0 Nbl1 / Borealin N terminal Meis_PKNOX_N PF16493.5 EKX38304.1 - 0.66 10.3 5.5 2.5 8.5 0.3 3.0 3 0 0 3 3 3 0 N-terminal of Homeobox Meis and PKNOX1 Ank_4 PF13637.6 EKX38305.1 - 4.4e-14 52.6 0.0 8.8e-10 38.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX38305.1 - 1.2e-13 51.4 0.1 2e-13 50.7 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) PLAC8 PF04749.17 EKX38305.1 - 5.6e-13 49.7 9.7 5.6e-13 49.7 9.7 2.0 2 1 0 2 2 2 1 PLAC8 family Ank_5 PF13857.6 EKX38305.1 - 2.7e-11 43.5 0.2 1.7e-06 28.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX38305.1 - 1.4e-09 38.0 0.0 0.032 14.7 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EKX38305.1 - 2.7e-07 30.3 0.0 0.0074 16.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat YfmQ PF10787.9 EKX38305.1 - 0.051 13.3 0.0 0.077 12.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein from bacillus cereus group PI3_PI4_kinase PF00454.27 EKX38308.1 - 2.8e-42 145.3 0.1 3.8e-42 144.8 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EKX38308.1 - 2.3e-14 52.9 0.0 4e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 FATC domain COR PF16095.5 EKX38310.1 - 2.5e-25 89.5 0.0 4.6e-25 88.6 0.0 1.5 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain SPRY PF00622.28 EKX38310.1 - 5.1e-20 71.8 0.0 1.4e-08 34.9 0.0 2.8 3 0 0 3 3 2 2 SPRY domain TIR_2 PF13676.6 EKX38310.1 - 1.8e-18 67.3 0.0 1.2e-07 32.3 0.0 3.4 3 0 0 3 3 3 2 TIR domain Roc PF08477.13 EKX38310.1 - 2.3e-18 66.6 0.0 3.5e-12 46.6 0.0 2.7 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EKX38310.1 - 5.7e-12 45.5 0.0 9.7e-10 38.3 0.0 2.4 1 1 0 1 1 1 1 Ras family LRR_4 PF12799.7 EKX38310.1 - 5.9e-08 32.9 14.8 0.019 15.4 0.1 5.2 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX38310.1 - 3.7e-06 26.6 12.5 0.016 14.9 1.6 3.9 3 0 0 3 3 3 3 Leucine rich repeat ABC_tran PF00005.27 EKX38310.1 - 0.00024 21.6 0.0 0.00071 20.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter DUF3037 PF11236.8 EKX38310.1 - 0.0057 17.1 0.4 0.027 14.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3037) LRR_6 PF13516.6 EKX38310.1 - 0.015 15.3 0.7 0.32 11.1 0.0 3.1 2 0 0 2 2 2 0 Leucine Rich repeat 40S_S4_C PF16121.5 EKX38310.1 - 0.02 14.5 0.1 4.9 6.9 0.1 2.6 2 0 0 2 2 2 0 40S ribosomal protein S4 C-terminus AAA_16 PF13191.6 EKX38310.1 - 0.025 14.9 0.0 0.1 13.0 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain DUF2635 PF10948.8 EKX38310.1 - 0.061 13.1 0.0 18 5.1 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2635) Phage-tail_3 PF13550.6 EKX38310.1 - 0.11 12.4 0.0 22 4.8 0.0 2.4 2 0 0 2 2 2 0 Putative phage tail protein DUF1863 PF08937.11 EKX38310.1 - 0.12 12.6 0.0 0.52 10.6 0.0 2.1 1 0 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) Chloroa_b-bind PF00504.21 EKX38311.1 - 9.5e-38 130.3 0.3 1.2e-37 129.9 0.3 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Zn_clus PF00172.18 EKX38312.1 - 1.4e-06 28.3 10.3 1.4e-06 28.3 10.3 2.5 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DiS_P_DiS PF06750.13 EKX38312.1 - 0.094 12.8 14.6 0.048 13.8 2.6 2.2 1 1 1 2 2 2 0 Bacterial Peptidase A24 N-terminal domain S1 PF00575.23 EKX38313.1 - 8.2e-13 48.5 0.3 8.2e-13 48.5 0.3 1.7 2 0 0 2 2 2 1 S1 RNA binding domain zf-RanBP PF00641.18 EKX38313.1 - 0.00022 20.4 4.7 0.00041 19.6 4.7 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zinc-ribbon_6 PF10005.9 EKX38313.1 - 0.052 14.2 0.1 0.052 14.2 0.1 1.9 2 0 0 2 2 2 0 zinc-ribbon domain Vfa1 PF08432.10 EKX38313.1 - 3.5 7.9 18.9 5.3 7.3 18.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RNA_polI_A34 PF08208.11 EKX38313.1 - 3.5 7.7 24.1 6 6.9 24.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Rtf2 PF04641.12 EKX38313.1 - 5 6.4 22.4 8.7 5.6 22.4 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Nucleoporin_N PF08801.11 EKX38314.1 - 4.9e-19 68.4 0.0 3.3e-18 65.7 0.0 2.2 1 1 0 1 1 1 1 Nup133 N terminal like SesA PF17107.5 EKX38314.1 - 0.056 13.6 1.0 0.42 10.8 0.3 2.7 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases PDZ_6 PF17820.1 EKX38316.1 - 1.9e-14 53.2 0.1 5.2e-14 51.8 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX38316.1 - 3.2e-10 40.2 0.5 1.6e-09 38.0 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX38316.1 - 1.2e-08 35.1 0.0 3.3e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 EKX38316.1 - 6.4e-05 23.3 0.5 0.00056 20.2 0.0 2.5 1 1 0 2 2 2 1 GRASP55/65 PDZ-like domain Tricorn_PDZ PF14685.6 EKX38316.1 - 0.0059 16.5 0.2 0.023 14.6 0.1 2.0 2 0 0 2 2 2 1 Tricorn protease PDZ domain LRR_4 PF12799.7 EKX38317.1 - 2.8e-08 33.9 0.0 9.8e-05 22.7 0.1 2.3 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EKX38317.1 - 1.3e-06 28.0 5.4 0.018 15.1 0.0 3.6 3 0 0 3 3 3 2 Leucine Rich repeat LRR_8 PF13855.6 EKX38317.1 - 0.00012 21.8 0.5 0.9 9.3 1.9 3.4 2 2 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 EKX38317.1 - 0.0043 17.4 0.2 37 5.4 0.6 4.0 3 1 0 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.6 EKX38318.1 - 0.024 14.7 1.3 1.9 8.8 0.2 2.8 3 0 0 3 3 3 0 Leucine Rich repeat DUF819 PF05684.12 EKX38319.1 - 9.7e-41 140.1 9.5 1.4e-40 139.5 9.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF819) Fe_bilin_red PF05996.12 EKX38320.1 - 2e-65 220.7 0.2 2.5e-65 220.4 0.2 1.0 1 0 0 1 1 1 1 Ferredoxin-dependent bilin reductase Peptidase_C13 PF01650.18 EKX38321.1 - 2.2e-91 305.9 0.0 3e-91 305.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family ETRAMP PF09716.10 EKX38322.1 - 0.037 14.1 0.0 0.087 12.9 0.0 1.6 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Herpes_glycop PF01528.16 EKX38322.1 - 0.11 11.3 1.9 0.077 11.8 0.2 1.4 2 0 0 2 2 2 0 Herpesvirus glycoprotein M EphA2_TM PF14575.6 EKX38322.1 - 0.22 12.4 0.3 1.1 10.2 0.1 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain FlxA PF14282.6 EKX38323.1 - 0.00029 20.8 1.8 0.00062 19.7 1.8 1.4 1 0 0 1 1 1 1 FlxA-like protein PDZ_6 PF17820.1 EKX38323.1 - 0.0071 16.2 0.1 0.57 10.1 0.0 2.5 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX38323.1 - 0.0073 16.6 1.7 0.0081 16.5 0.1 1.9 2 0 0 2 2 2 1 PDZ domain DUF724 PF05266.14 EKX38323.1 - 0.019 14.8 1.9 0.039 13.8 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ROS_MUCR PF05443.11 EKX38323.1 - 0.022 14.8 1.3 0.088 12.8 0.5 2.1 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein DUF693 PF05113.13 EKX38323.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF693) p47_phox_C PF08944.11 EKX38323.1 - 0.62 9.5 3.0 1.2 8.6 3.0 1.4 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain PH PF00169.29 EKX38325.1 - 0.00055 20.4 0.7 0.0066 16.9 0.1 2.6 2 1 0 2 2 2 1 PH domain GYF_2 PF14237.6 EKX38325.1 - 0.011 15.5 0.8 0.035 13.9 0.0 2.2 3 0 0 3 3 3 0 GYF domain 2 PDZ_2 PF13180.6 EKX38327.1 - 1.8e-07 31.4 0.3 0.28 11.5 0.0 3.9 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 EKX38327.1 - 0.00013 21.7 0.0 0.051 13.4 0.0 3.0 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 EKX38327.1 - 0.0037 17.6 1.2 0.089 13.2 0.1 3.4 3 0 0 3 3 3 1 PDZ domain Lebercilin PF15619.6 EKX38327.1 - 0.0086 15.8 12.7 0.0086 15.8 12.7 3.6 3 1 0 3 3 3 1 Ciliary protein causing Leber congenital amaurosis disease CENP-B_N PF04218.13 EKX38327.1 - 1.1 8.9 10.5 0.062 12.9 0.9 3.6 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain Transformer PF06495.11 EKX38327.1 - 6.7 6.8 9.4 0.28 11.3 3.0 1.9 2 0 0 2 2 2 0 Fruit fly transformer protein GST_N_3 PF13417.6 EKX38328.1 - 1.6e-05 25.2 0.0 2.9e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EKX38328.1 - 0.00011 22.5 0.0 0.00018 21.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EKX38328.1 - 0.0054 17.1 0.0 0.01 16.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PseudoU_synth_1 PF01416.20 EKX38329.1 - 3.5e-10 40.3 0.0 2.7e-09 37.5 0.0 2.1 1 1 0 1 1 1 1 tRNA pseudouridine synthase Sel1 PF08238.12 EKX38330.1 - 4.9e-14 52.5 14.0 0.00074 20.1 0.2 4.6 4 1 0 4 4 4 4 Sel1 repeat FKBP_N PF01346.18 EKX38330.1 - 3.1 8.8 8.2 2 9.4 4.1 2.3 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase GAF PF01590.26 EKX38331.1 - 7e-05 23.5 0.0 8.4e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 EKX38331.1 - 0.0052 17.1 0.0 0.0068 16.7 0.0 1.2 1 0 0 1 1 1 1 GAF domain FR47 PF08445.10 EKX38331.1 - 0.14 12.1 0.0 23 5.0 0.0 2.2 2 0 0 2 2 2 0 FR47-like protein Ank_4 PF13637.6 EKX38332.1 - 1.4e-20 73.3 0.2 2e-10 41.0 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX38332.1 - 3.5e-14 52.5 0.0 7.2e-06 26.2 0.0 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EKX38332.1 - 5.5e-14 50.9 0.1 5.5e-07 29.4 0.0 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EKX38332.1 - 1.8e-13 50.9 0.3 3.7e-13 49.8 0.3 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX38332.1 - 2.4e-13 50.0 0.1 3.5e-13 49.5 0.1 1.3 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX38333.1 - 5.5e-13 49.1 0.1 2.2e-07 31.3 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX38333.1 - 6.4e-10 39.5 0.0 7e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX38333.1 - 8.7e-08 32.3 0.2 2.7e-05 24.4 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EKX38333.1 - 7e-07 29.1 0.0 0.0017 18.7 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EKX38333.1 - 0.00018 21.7 0.0 0.00061 20.0 0.0 1.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX38334.1 - 2.3e-28 98.2 2.5 2.9e-08 34.1 0.2 4.4 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX38334.1 - 4.1e-27 94.6 6.5 2.9e-10 40.6 2.7 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX38334.1 - 9.4e-22 76.8 6.0 3e-07 30.6 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX38334.1 - 6.4e-20 70.7 8.5 1e-05 25.8 0.4 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 EKX38334.1 - 3e-17 60.9 6.5 8e-05 22.8 0.1 6.0 6 0 0 6 6 6 3 Ankyrin repeat SPRY PF00622.28 EKX38335.1 - 3.6e-26 91.6 0.1 7.2e-26 90.7 0.1 1.6 1 0 0 1 1 1 1 SPRY domain U-box PF04564.15 EKX38335.1 - 3.2e-10 40.1 0.0 7.7e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 U-box domain XPG_I PF00867.18 EKX38336.1 - 3.1e-27 94.8 0.0 6.4e-27 93.7 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EKX38336.1 - 1.7e-25 89.4 0.0 3.5e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 EKX38336.1 - 0.014 15.9 0.0 0.038 14.6 0.0 1.7 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Mid1 PF12929.7 EKX38337.1 - 2.1e-05 23.9 23.1 0.00082 18.7 23.1 2.8 1 1 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component IF-2B PF01008.17 EKX38338.1 - 8.5e-59 199.1 0.1 1.1e-58 198.7 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Dak1 PF02733.17 EKX38338.1 - 0.036 13.0 0.0 0.055 12.3 0.0 1.3 1 0 0 1 1 1 0 Dak1 domain Bin3 PF06859.12 EKX38339.1 - 2.6e-38 131.0 0.0 3.5e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_12 PF08242.12 EKX38339.1 - 0.0031 18.2 0.0 0.0047 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX38339.1 - 0.055 13.3 0.0 0.063 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PDZ PF00595.24 EKX38340.1 - 4.4e-13 49.4 3.4 5.4e-10 39.5 1.3 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EKX38340.1 - 8.4e-11 41.5 4.6 5.6e-09 35.7 0.3 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX38340.1 - 8e-10 38.9 0.3 9.5e-08 32.3 0.1 2.5 2 0 0 2 2 2 1 PDZ domain DUF948 PF06103.11 EKX38340.1 - 0.0076 16.5 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) Tricorn_PDZ PF14685.6 EKX38340.1 - 0.063 13.3 0.1 0.28 11.2 0.0 2.1 2 0 0 2 2 2 0 Tricorn protease PDZ domain adh_short PF00106.25 EKX38341.1 - 4.1e-35 121.0 0.0 6.3e-24 84.5 0.0 2.0 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EKX38341.1 - 1.9e-25 89.8 0.0 1.1e-14 54.5 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX38341.1 - 9.4e-07 28.9 0.0 1.3e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EKX38341.1 - 0.0062 16.0 0.0 0.0088 15.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EKX38341.1 - 0.23 10.8 0.0 0.33 10.3 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Cpn60_TCP1 PF00118.24 EKX38342.1 - 4.4e-167 556.6 5.1 5e-167 556.4 5.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Asp23 PF03780.13 EKX38343.1 - 0.043 14.2 0.1 0.11 12.9 0.1 1.6 1 1 0 1 1 1 0 Asp23 family, cell envelope-related function Sfi1 PF08457.10 EKX38344.1 - 0.0073 14.9 5.0 0.0091 14.6 5.0 1.0 1 0 0 1 1 1 1 Sfi1 spindle body protein Arm_3 PF16186.5 EKX38344.1 - 0.06 12.9 5.7 0.049 13.2 2.7 2.5 2 1 0 2 2 2 0 Atypical Arm repeat DJ-1_PfpI PF01965.24 EKX38345.1 - 2.1e-27 95.9 0.1 2.5e-27 95.7 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Ribul_P_3_epim PF00834.19 EKX38346.1 - 1.4e-36 125.7 0.0 1.8e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family UvrC_HhH_N PF08459.11 EKX38346.1 - 0.034 14.1 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal UPF0181 PF03701.14 EKX38346.1 - 0.1 12.3 0.1 0.66 9.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) PdxJ PF03740.13 EKX38346.1 - 0.11 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ DUF1054 PF06335.12 EKX38346.1 - 0.12 12.2 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1054) FGGY_C PF02782.16 EKX38347.1 - 3.7e-32 111.7 0.1 7.8e-32 110.6 0.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EKX38347.1 - 6.9e-26 91.3 1.0 1e-11 44.9 1.4 3.1 1 1 1 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain TcfC PF16967.5 EKX38348.1 - 0.25 10.9 0.9 55 3.3 0.0 3.9 3 0 0 3 3 3 0 E-set like domain Toxin_2 PF00451.19 EKX38348.1 - 3.9 7.9 10.7 36 4.8 0.4 4.0 3 0 0 3 3 3 0 Scorpion short toxin, BmKK2 DNA_binding_1 PF01035.20 EKX38350.1 - 1.3e-10 41.2 0.0 3.6e-10 39.8 0.0 1.8 2 0 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain FAM176 PF14851.6 EKX38350.1 - 0.013 15.2 6.9 0.019 14.7 6.9 1.3 1 0 0 1 1 1 0 FAM176 family RPN2_C PF18004.1 EKX38350.1 - 0.026 14.4 6.0 0.038 13.9 6.0 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain NOA36 PF06524.12 EKX38350.1 - 0.033 13.5 9.4 0.048 13.0 9.4 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 EKX38350.1 - 0.045 11.9 9.3 0.053 11.6 9.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 EKX38350.1 - 0.059 11.7 12.2 0.07 11.4 12.2 1.0 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.8 EKX38350.1 - 0.13 12.5 12.7 0.05 13.8 10.5 1.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Ribosomal_60s PF00428.19 EKX38350.1 - 0.13 12.9 5.5 0.25 12.0 5.5 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF2457 PF10446.9 EKX38350.1 - 0.23 10.6 15.3 0.33 10.0 15.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pes-10 PF07149.11 EKX38350.1 - 0.42 9.6 4.9 0.47 9.5 4.9 1.1 1 0 0 1 1 1 0 Pes-10 Sporozoite_P67 PF05642.11 EKX38350.1 - 0.44 8.6 3.8 0.55 8.2 3.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nucleo_P87 PF07267.11 EKX38350.1 - 0.77 8.6 8.1 0.87 8.4 8.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RRN3 PF05327.11 EKX38350.1 - 8.8 4.7 7.6 11 4.4 7.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CENP-B_dimeris PF09026.10 EKX38350.1 - 9.2 6.7 16.0 16 6.0 16.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Tubulin PF00091.25 EKX38351.1 - 1.5e-67 227.6 0.0 2.7e-67 226.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EKX38351.1 - 3.4e-42 143.6 0.2 5e-42 143.0 0.2 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EKX38351.1 - 8.8e-05 22.8 0.0 0.00022 21.5 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EKX38351.1 - 0.0024 17.6 0.0 0.0044 16.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EKX38351.1 - 0.028 13.6 0.1 0.079 12.1 0.0 1.7 2 0 0 2 2 2 0 Tubulin like Het-C PF07217.11 EKX38351.1 - 0.11 11.0 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Ephrin_rec_like PF07699.13 EKX38352.1 - 4.6e-35 119.1 93.8 4.5e-09 35.9 5.6 8.5 3 1 5 8 8 8 8 Putative ephrin-receptor like NCD3G PF07562.14 EKX38352.1 - 2.1e-14 53.2 69.8 0.00022 21.1 2.4 8.6 4 1 4 9 9 9 9 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX38352.1 - 1.5e-09 38.1 68.4 0.053 13.9 0.4 11.5 3 2 8 11 11 11 10 TNFR/NGFR cysteine-rich region VSP PF03302.13 EKX38352.1 - 0.58 9.0 72.1 0.3 9.9 22.1 4.2 1 1 3 4 4 4 0 Giardia variant-specific surface protein Methyltransf_16 PF10294.9 EKX38353.1 - 4.9e-21 75.2 0.0 8.8e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 EKX38353.1 - 0.098 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) C2 PF00168.30 EKX38354.1 - 1.5e-07 31.7 0.0 2.1e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 C2 domain DUF1472 PF07339.12 EKX38354.1 - 0.11 13.0 0.0 0.4 11.2 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1472) OMPdecase PF00215.24 EKX38355.1 - 5.5e-71 238.7 0.0 8.3e-71 238.2 0.0 1.3 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 EKX38355.1 - 2.3e-12 46.7 0.1 4.4e-12 45.8 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain ubiquitin PF00240.23 EKX38356.1 - 8.9e-10 38.2 0.1 1.2e-09 37.7 0.1 1.3 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 EKX38356.1 - 1.1e-06 29.0 0.1 5.2e-06 26.8 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 EKX38356.1 - 0.0026 17.5 0.2 0.0086 15.9 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 EKX38356.1 - 0.046 13.8 0.1 0.46 10.6 0.1 1.9 1 1 1 2 2 2 0 Ubiquitin-like domain Peptidase_M28 PF04389.17 EKX38357.1 - 8e-23 81.2 0.0 9.3e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 E1_FCCH PF16190.5 EKX38358.1 - 0.049 13.8 0.1 0.067 13.4 0.1 1.4 1 1 0 1 1 1 0 Ubiquitin-activating enzyme E1 FCCH domain DUF1415 PF07209.12 EKX38359.1 - 7e-25 87.7 0.0 1.3e-16 60.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1415) DUF3244 PF11589.8 EKX38360.1 - 0.13 12.3 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3244) DUF4704 PF15787.5 EKX38361.1 - 0.012 14.9 0.4 0.012 14.9 0.4 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4704) SIL1 PF16782.5 EKX38361.1 - 0.047 12.9 3.8 0.83 8.8 0.1 3.2 3 0 0 3 3 3 0 Nucleotide exchange factor SIL1 DUF2650 PF10853.8 EKX38361.1 - 0.056 13.2 0.4 0.13 12.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) SHOCT PF09851.9 EKX38362.1 - 0.0032 17.2 0.2 0.043 13.6 0.1 2.1 2 0 0 2 2 2 1 Short C-terminal domain Mt_ATP-synt_B PF05405.14 EKX38362.1 - 0.067 12.8 0.0 0.071 12.7 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) fn3 PF00041.21 EKX38363.1 - 2e-15 56.9 14.3 0.0095 16.3 0.1 11.0 10 1 0 10 10 10 5 Fibronectin type III domain EPTP PF03736.17 EKX38363.1 - 4.1e-12 45.9 5.2 3.2e-06 27.0 0.2 4.3 3 0 0 3 3 3 3 EPTP domain DUF2808 PF10989.8 EKX38363.1 - 0.014 15.4 16.1 0.76 9.8 0.1 7.9 9 0 0 9 9 9 0 Protein of unknown function (DUF2808) LysM PF01476.20 EKX38363.1 - 0.058 13.5 0.0 0.27 11.3 0.0 2.2 1 0 0 1 1 1 0 LysM domain Kelch_1 PF01344.25 EKX38364.1 - 1.4e-09 37.4 0.7 0.024 14.2 0.1 3.4 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 EKX38364.1 - 0.00071 19.8 0.2 14 6.2 0.0 3.5 3 0 0 3 3 3 3 Kelch motif Ribosomal_S27 PF01599.19 EKX38365.1 - 3.9e-23 81.3 5.3 3.9e-23 81.3 5.3 2.0 3 0 0 3 3 3 1 Ribosomal protein S27a ubiquitin PF00240.23 EKX38365.1 - 5.4e-08 32.5 0.1 1.2e-07 31.4 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 EKX38365.1 - 0.088 13.3 0.1 0.33 11.5 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like domain Rad60-SLD PF11976.8 EKX38365.1 - 0.15 11.9 0.9 0.32 10.9 0.1 1.9 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Dus PF01207.17 EKX38366.1 - 4.6e-74 249.3 0.0 5.3e-74 249.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) NMO PF03060.15 EKX38366.1 - 0.018 14.4 0.0 0.23 10.8 0.0 2.0 1 1 1 2 2 2 0 Nitronate monooxygenase SOR_SNZ PF01680.17 EKX38366.1 - 0.033 14.0 0.1 0.79 9.5 0.0 2.2 1 1 1 2 2 2 0 SOR/SNZ family His_biosynth PF00977.21 EKX38366.1 - 0.043 13.3 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein DHO_dh PF01180.21 EKX38366.1 - 0.081 12.1 0.0 1.6 7.9 0.0 2.0 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 EKX38366.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator MORN PF02493.20 EKX38368.1 - 1.2e-46 153.9 60.4 9.2e-08 31.6 1.2 9.4 9 0 0 9 9 9 9 MORN repeat DUF3048_C PF17479.2 EKX38368.1 - 0.042 14.2 0.2 0.042 14.2 0.2 4.2 2 2 0 2 2 2 0 Protein of unknown function (DUF3048) C-terminal domain Pkinase_Tyr PF07714.17 EKX38369.1 - 5.2e-33 114.4 0.0 6e-33 114.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX38369.1 - 2.1e-13 50.3 0.0 2.3e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain KH_1 PF00013.29 EKX38370.1 - 0.00018 21.3 0.0 0.00032 20.5 0.0 1.4 1 0 0 1 1 1 1 KH domain Ribosomal_S7e PF01251.18 EKX38371.1 - 1.2e-82 276.2 5.9 1.3e-82 276.0 5.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e HEAT_2 PF13646.6 EKX38372.1 - 3.2e-08 33.9 3.0 2.8e-05 24.4 0.7 2.9 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 EKX38372.1 - 0.00021 21.3 0.1 2.2 8.8 0.0 3.2 3 0 0 3 3 3 2 HEAT repeat Adaptin_N PF01602.20 EKX38372.1 - 0.089 11.3 0.1 0.48 8.9 0.0 1.8 1 1 1 2 2 2 0 Adaptin N terminal region HEAT PF02985.22 EKX38373.1 - 2.8e-24 83.1 8.5 8.4e-05 22.5 0.0 8.8 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.6 EKX38373.1 - 1.6e-15 57.3 3.4 0.00017 21.9 0.0 4.2 2 2 0 3 3 3 3 HEAT repeats Vac14_Fab1_bd PF12755.7 EKX38373.1 - 7.8e-06 26.4 0.6 0.41 11.3 0.0 4.2 4 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region TAF6_C PF07571.13 EKX38373.1 - 0.0026 18.0 0.0 7.6 6.9 0.0 3.7 3 0 0 3 3 3 1 TAF6 C-terminal HEAT repeat domain IFRD PF05004.13 EKX38373.1 - 0.0031 16.7 0.0 0.33 10.0 0.0 2.5 2 0 0 2 2 2 2 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 EKX38373.1 - 0.012 16.1 8.1 1 9.9 0.0 5.2 5 2 2 7 7 7 0 HEAT-like repeat Arm PF00514.23 EKX38373.1 - 0.033 14.2 1.7 2.8 8.1 0.0 4.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DUF1427 PF07235.11 EKX38373.1 - 0.069 13.1 0.3 17 5.5 0.0 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF1427) Ephrin_rec_like PF07699.13 EKX38374.1 - 8.5e-54 179.1 114.3 5.6e-09 35.6 6.1 12.0 5 4 7 12 12 12 11 Putative ephrin-receptor like NCD3G PF07562.14 EKX38374.1 - 6.9e-16 58.0 89.2 0.00021 21.2 6.8 11.0 8 4 2 10 10 10 10 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX38374.1 - 0.0012 19.1 86.0 0.066 13.6 1.4 14.5 6 5 8 15 15 15 8 TNFR/NGFR cysteine-rich region VSP PF03302.13 EKX38374.1 - 1.1 8.1 86.4 0.099 11.5 17.3 5.5 1 1 2 4 4 4 0 Giardia variant-specific surface protein PHO4 PF01384.20 EKX38375.1 - 4.3e-107 358.1 18.7 5.3e-107 357.8 18.7 1.1 1 0 0 1 1 1 1 Phosphate transporter family DPM3 PF08285.11 EKX38375.1 - 0.034 14.3 4.3 0.086 13.0 0.4 3.0 2 1 1 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) tRNA-synt_1c PF00749.21 EKX38376.1 - 5.8e-67 225.8 0.0 9.3e-67 225.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EKX38376.1 - 4.5e-20 72.2 0.0 8.4e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain FAA_hydro_N_2 PF18288.1 EKX38378.1 - 0.098 13.1 0.1 0.45 11.0 0.1 2.0 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 DHO_dh PF01180.21 EKX38380.1 - 5.9e-98 327.7 0.0 8e-98 327.3 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 EKX38380.1 - 0.058 12.8 0.2 0.095 12.1 0.2 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase SANT_DAMP1_like PF16282.5 EKX38381.1 - 6.2e-23 80.8 2.9 2.8e-22 78.7 2.9 2.0 1 1 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DUF2742 PF10888.8 EKX38381.1 - 0.11 12.7 0.1 0.24 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2742) 2OG-FeII_Oxy_3 PF13640.6 EKX38383.1 - 1.8e-09 38.4 0.1 3e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 EKX38383.1 - 0.0039 17.6 0.0 0.0068 16.8 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase PHO4 PF01384.20 EKX38384.1 - 7.3e-107 357.3 19.9 8.5e-107 357.1 19.9 1.0 1 0 0 1 1 1 1 Phosphate transporter family DPM3 PF08285.11 EKX38384.1 - 0.1 12.8 5.1 0.11 12.7 0.4 3.1 2 1 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) SAM_PNT PF02198.16 EKX38386.1 - 0.0057 16.6 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain OST-HTH PF12872.7 EKX38386.1 - 0.025 14.4 0.0 0.07 13.0 0.0 1.7 1 0 0 1 1 1 0 OST-HTH/LOTUS domain AKAP7_NLS PF10469.9 EKX38387.1 - 8.8e-28 97.6 0.0 1.1e-27 97.3 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 EKX38387.1 - 1.8e-05 24.7 0.0 2.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily PHO4 PF01384.20 EKX38388.1 - 3.1e-104 348.7 28.5 3.6e-104 348.5 28.5 1.0 1 0 0 1 1 1 1 Phosphate transporter family DPM3 PF08285.11 EKX38388.1 - 0.1 12.8 5.0 0.12 12.6 0.4 2.9 2 1 1 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) TMEM132D_N PF15705.5 EKX38389.1 - 0.057 13.3 1.0 0.14 12.0 1.0 1.6 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term AMP-binding PF00501.28 EKX38389.1 - 0.33 9.5 3.1 0.5 8.9 2.4 1.9 1 1 0 1 1 1 0 AMP-binding enzyme RmlD_sub_bind PF04321.17 EKX38390.1 - 2.2e-39 135.3 0.0 2.8e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EKX38390.1 - 3.3e-22 79.1 0.0 4.2e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EKX38390.1 - 1.9e-12 47.2 0.0 3e-12 46.6 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EKX38390.1 - 0.00028 20.1 0.4 0.006 15.7 0.4 2.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EKX38390.1 - 0.00041 19.6 0.0 0.35 10.0 0.0 2.6 2 1 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 EKX38390.1 - 0.0081 15.2 0.0 0.024 13.7 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Pkinase PF00069.25 EKX38391.1 - 1e-53 182.4 0.0 1.1e-53 182.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX38391.1 - 1.1e-28 100.2 0.0 1.4e-28 99.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX38391.1 - 0.00018 20.9 0.0 0.00033 20.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EKX38391.1 - 0.0021 17.4 0.4 0.003 17.0 0.4 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EKX38391.1 - 0.019 13.8 0.0 0.078 11.7 0.0 1.7 1 1 1 2 2 2 0 Fungal protein kinase Cmc1 PF08583.10 EKX38391.1 - 0.035 14.1 1.0 0.058 13.4 1.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like APH_6_hur PF04655.14 EKX38391.1 - 0.099 12.0 0.1 7.7 5.8 0.0 2.1 1 1 1 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase PAP_fibrillin PF04755.12 EKX38392.1 - 5.8e-19 68.8 0.0 7.9e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 PAP_fibrillin FAP206 PF12018.8 EKX38393.1 - 0.12 11.8 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function Yip1 PF04893.17 EKX38394.1 - 1.5e-09 37.8 5.1 1.8e-09 37.6 5.1 1.2 1 0 0 1 1 1 1 Yip1 domain PilX_N PF14341.6 EKX38394.1 - 0.31 11.0 3.7 1 9.4 0.2 2.5 2 0 0 2 2 2 0 PilX N-terminal CUB PF00431.20 EKX38396.1 - 0.00012 22.4 0.0 0.00043 20.6 0.0 1.9 1 0 0 1 1 1 1 CUB domain SWM_repeat PF13753.6 EKX38396.1 - 4.9 7.4 11.6 2.3 8.5 0.0 5.5 5 0 0 5 5 5 0 Putative flagellar system-associated repeat Ank PF00023.30 EKX38397.1 - 1.5e-11 44.2 0.2 1.4e-05 25.3 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EKX38397.1 - 1.6e-10 41.4 0.3 3.1e-10 40.5 0.3 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX38397.1 - 8.2e-10 39.0 0.9 1.1e-06 29.1 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX38397.1 - 8.3e-07 28.8 0.1 0.015 15.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EKX38397.1 - 0.0002 21.6 0.1 0.00074 19.8 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Sulfotransfer_3 PF13469.6 EKX38398.1 - 6.2e-33 115.0 0.3 2.1e-32 113.3 0.3 1.8 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 EKX38398.1 - 1.2e-11 44.6 4.7 2.2e-11 43.8 4.7 1.4 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 EKX38398.1 - 0.0076 16.1 1.5 0.16 11.8 0.5 2.8 2 1 0 2 2 2 1 Sulfotransferase domain SPA PF08616.10 EKX38398.1 - 0.046 13.7 0.1 2.6 8.0 0.1 2.5 2 0 0 2 2 2 0 Stabilization of polarity axis C2 PF00168.30 EKX38399.1 - 0.00011 22.4 0.0 0.00021 21.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain DASH_Hsk3 PF08227.11 EKX38400.1 - 0.015 15.7 0.5 0.039 14.3 0.5 1.7 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like DUF4363 PF14276.6 EKX38400.1 - 0.14 12.2 5.4 0.39 10.8 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Lzipper-MIP1 PF14389.6 EKX38400.1 - 0.17 12.2 10.1 0.067 13.5 1.4 2.4 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF4407 PF14362.6 EKX38400.1 - 3.1 7.1 11.4 9.3 5.5 11.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) adh_short PF00106.25 EKX38401.1 - 9.6e-08 31.7 0.0 8.1e-06 25.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EKX38401.1 - 1.3e-06 28.1 0.0 3.5e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Speriolin_N PF15058.6 EKX38401.1 - 0.1 12.6 0.1 0.2 11.7 0.0 1.4 1 1 0 1 1 1 0 Speriolin N terminus EF-hand_6 PF13405.6 EKX38404.1 - 9.7e-07 28.2 0.2 0.063 13.2 0.0 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EKX38404.1 - 1.7e-05 24.0 0.1 0.0059 16.1 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EKX38404.1 - 0.00096 19.6 0.0 1 9.8 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair DUF2475 PF10629.9 EKX38404.1 - 1.3 9.3 7.0 7.8 6.8 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2475) cNMP_binding PF00027.29 EKX38406.1 - 1.2e-40 137.5 0.2 1.4e-20 73.2 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain C2 PF00168.30 EKX38406.1 - 1.4e-06 28.5 0.0 3.4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain Cupin_2 PF07883.11 EKX38406.1 - 0.035 13.8 0.4 1.3 8.8 0.0 2.5 2 0 0 2 2 2 0 Cupin domain Beta_helix PF13229.6 EKX38409.1 - 0.0002 21.2 0.0 0.00026 20.9 0.0 1.2 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 EKX38409.1 - 0.056 12.7 0.0 0.31 10.3 0.0 1.4 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) PHO4 PF01384.20 EKX38410.1 - 1.8e-104 349.5 19.5 2.5e-104 349.0 19.5 1.2 1 0 0 1 1 1 1 Phosphate transporter family Caveolin PF01146.17 EKX38410.1 - 3.2 7.7 7.3 0.39 10.7 0.4 2.7 2 1 0 2 2 2 0 Caveolin DPM3 PF08285.11 EKX38410.1 - 6.5 7.0 5.7 3.2 8.0 0.3 3.0 2 2 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) HisKA PF00512.25 EKX38412.1 - 1.2e-16 60.4 0.3 2.5e-16 59.5 0.3 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c PF02518.26 EKX38412.1 - 3.1e-13 50.2 0.0 4.7e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EKX38412.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.5 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain Polyketide_cyc2 PF10604.9 EKX38413.1 - 1.4e-12 48.1 2.8 1.5e-12 47.9 2.8 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EKX38413.1 - 2.5e-10 40.7 2.3 2.8e-10 40.5 2.3 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport AHSA1 PF08327.11 EKX38413.1 - 3.5e-06 27.3 1.6 4.4e-06 26.9 1.6 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein DUF3444 PF11926.8 EKX38413.1 - 0.01 15.5 0.1 0.012 15.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3444) PWWP PF00855.17 EKX38414.1 - 2.4e-14 53.5 0.3 2.4e-14 53.5 0.3 4.4 2 1 1 3 3 3 1 PWWP domain PHD PF00628.29 EKX38414.1 - 2.8e-08 33.5 7.2 6.6e-08 32.3 7.2 1.7 1 0 0 1 1 1 1 PHD-finger HMG_box PF00505.19 EKX38414.1 - 6.2e-08 32.9 3.4 6.2e-08 32.9 3.4 3.6 4 0 0 4 4 4 1 HMG (high mobility group) box PHD_2 PF13831.6 EKX38414.1 - 1.2e-05 24.7 2.5 2.8e-05 23.6 2.5 1.7 1 0 0 1 1 1 1 PHD-finger RRM_1 PF00076.22 EKX38414.1 - 0.00061 19.6 0.0 0.6 10.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) C1_1 PF00130.22 EKX38414.1 - 7.6 6.5 7.6 1.4 8.9 2.8 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GAF_2 PF13185.6 EKX38415.1 - 9.8e-29 100.4 1.3 3.3e-07 30.7 0.0 8.0 7 1 0 7 7 7 6 GAF domain GAF PF01590.26 EKX38415.1 - 2.9e-28 99.2 3.2 1.9e-06 28.5 0.0 7.9 7 2 0 7 7 7 6 GAF domain GAF_3 PF13492.6 EKX38415.1 - 5e-17 62.5 3.4 0.014 15.7 0.0 8.3 7 1 1 8 8 8 5 GAF domain DUF4724 PF15852.5 EKX38415.1 - 0.16 12.5 1.1 17 6.0 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4724) Hce2 PF14856.6 EKX38416.1 - 0.023 15.0 0.6 0.13 12.6 0.3 2.2 2 1 0 2 2 2 0 Pathogen effector; putative necrosis-inducing factor DUF4450 PF14614.6 EKX38416.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4450) Syntaxin_2 PF14523.6 EKX38418.1 - 1.7e-14 54.0 4.2 1.7e-14 54.0 4.2 2.4 2 1 0 2 2 2 1 Syntaxin-like protein Syntaxin PF00804.25 EKX38418.1 - 2.3e-11 43.7 13.2 2.3e-11 43.7 13.2 1.5 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 EKX38418.1 - 9.2e-10 38.4 0.2 9.2e-10 38.4 0.2 2.4 2 0 0 2 2 2 1 SNARE domain Borrelia_orfA PF02414.15 EKX38418.1 - 0.027 14.2 0.7 0.047 13.4 0.7 1.4 1 1 0 1 1 1 0 Borrelia ORF-A MCPsignal PF00015.21 EKX38418.1 - 0.029 14.2 3.4 0.044 13.6 0.5 2.4 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Prominin PF05478.11 EKX38418.1 - 0.032 12.2 5.2 0.059 11.3 5.2 1.4 1 1 0 1 1 1 0 Prominin Synaptobrevin PF00957.21 EKX38418.1 - 0.75 9.6 5.6 0.11 12.4 0.6 2.2 3 0 0 3 3 3 0 Synaptobrevin Pex19 PF04614.12 EKX38418.1 - 1.7 8.3 11.7 0.12 12.1 6.0 1.8 1 1 1 2 2 2 0 Pex19 protein family TMPIT PF07851.13 EKX38418.1 - 2.5 7.2 7.8 6.4 5.9 7.8 1.7 1 1 0 1 1 1 0 TMPIT-like protein DUF2207 PF09972.9 EKX38418.1 - 3.3 6.4 6.1 5.7 5.6 0.3 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) PDZ_6 PF17820.1 EKX38419.1 - 0.025 14.4 0.6 0.31 10.9 0.0 2.6 2 1 0 2 2 2 0 PDZ domain Ntox17 PF15524.6 EKX38420.1 - 0.017 15.4 0.0 0.036 14.4 0.0 1.5 1 0 0 1 1 1 0 Novel toxin 17 Metallophos PF00149.28 EKX38421.1 - 9.2e-23 81.8 0.0 2e-22 80.7 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CAP_GLY PF01302.25 EKX38421.1 - 1.5e-21 76.2 1.5 3.3e-21 75.1 1.5 1.6 1 0 0 1 1 1 1 CAP-Gly domain EF-hand_1 PF00036.32 EKX38421.1 - 2.2e-19 67.5 3.7 0.00011 21.4 0.0 6.3 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 EKX38421.1 - 1.9e-15 55.4 2.0 0.0058 16.5 0.0 6.3 6 0 0 6 6 6 3 EF-hand domain EF-hand_7 PF13499.6 EKX38421.1 - 1e-13 51.5 1.3 5.5e-07 30.0 0.2 3.8 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX38421.1 - 3e-09 35.9 2.2 0.051 13.1 0.6 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EKX38421.1 - 2.6e-08 33.6 4.7 0.00064 19.5 0.1 4.4 4 1 1 5 5 5 3 EF-hand domain pair Dockerin_1 PF00404.18 EKX38421.1 - 5.1e-05 23.4 1.1 0.014 15.6 0.0 3.9 2 2 1 3 3 3 2 Dockerin type I domain EF-hand_4 PF12763.7 EKX38421.1 - 0.044 13.7 0.6 5.4 7.0 0.0 3.6 4 0 0 4 4 4 0 Cytoskeletal-regulatory complex EF hand DUF4264 PF14084.6 EKX38421.1 - 0.045 13.4 3.5 1.1 8.9 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4264) SPARC_Ca_bdg PF10591.9 EKX38421.1 - 0.069 13.5 1.0 99 3.3 0.0 3.9 4 0 0 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region SH3_1 PF00018.28 EKX38421.1 - 0.16 11.6 0.5 0.32 10.6 0.5 1.5 1 0 0 1 1 1 0 SH3 domain VWA_CoxE PF05762.14 EKX38424.1 - 0.07 12.5 0.7 0.072 12.5 0.7 1.1 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein AAA_5 PF07728.14 EKX38425.1 - 4.9e-103 340.8 0.2 3.4e-28 98.4 0.0 9.6 8 1 1 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 EKX38425.1 - 4.1e-45 152.3 16.1 8.3e-13 48.5 0.1 6.2 6 1 0 6 6 5 4 Midasin AAA lid domain AAA_3 PF07726.11 EKX38425.1 - 9.6e-30 103.1 0.0 1e-07 31.9 0.0 7.9 6 2 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 EKX38425.1 - 2.8e-27 95.8 0.1 0.00014 22.2 0.0 6.1 5 0 0 5 5 5 5 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EKX38425.1 - 1.6e-26 92.9 0.5 3.8e-07 29.8 0.0 5.9 5 0 0 5 5 5 4 P-loop containing dynein motor region AAA_16 PF13191.6 EKX38425.1 - 5.9e-26 91.9 5.3 5.3e-07 30.2 0.2 6.1 6 0 0 6 6 5 5 AAA ATPase domain AAA_lid_5 PF17865.1 EKX38425.1 - 8.7e-26 90.1 1.7 1.3e-25 89.5 0.3 2.1 2 0 0 2 2 1 1 Midasin AAA lid domain Dynein_heavy PF03028.15 EKX38425.1 - 8.9e-20 71.0 0.0 7.2e-05 22.9 0.0 6.2 5 0 0 5 5 5 4 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 EKX38425.1 - 1.5e-18 67.4 0.0 0.00093 19.5 0.0 6.1 5 0 0 5 5 5 4 AAA domain AAA_6 PF12774.7 EKX38425.1 - 2.2e-18 66.3 5.3 0.0072 15.3 0.0 8.1 7 1 2 9 9 8 5 Hydrolytic ATP binding site of dynein motor region TsaE PF02367.17 EKX38425.1 - 2e-17 63.4 4.8 0.0019 18.2 0.1 5.4 5 0 0 5 5 5 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EKX38425.1 - 2.2e-17 63.8 0.3 0.011 16.3 0.0 6.2 5 0 0 5 5 5 4 AAA domain Sigma54_activat PF00158.26 EKX38425.1 - 6.6e-14 52.0 5.4 0.0054 16.4 0.0 5.4 7 0 0 7 7 4 3 Sigma-54 interaction domain AAA_30 PF13604.6 EKX38425.1 - 4.3e-13 49.4 1.3 0.00042 20.1 0.0 6.2 6 0 0 6 6 6 2 AAA domain RuvB_N PF05496.12 EKX38425.1 - 1.8e-12 47.3 0.3 0.34 10.6 0.0 6.8 6 0 0 6 6 6 2 Holliday junction DNA helicase RuvB P-loop domain T2SSE PF00437.20 EKX38425.1 - 1.2e-11 44.2 0.4 0.026 13.6 0.1 4.7 5 0 0 5 5 4 3 Type II/IV secretion system protein ABC_tran PF00005.27 EKX38425.1 - 1.3e-11 45.1 0.1 0.1 13.1 0.0 5.5 5 0 0 5 5 5 2 ABC transporter AAA_33 PF13671.6 EKX38425.1 - 1.6e-11 44.5 1.7 0.15 12.2 0.0 5.8 5 0 0 5 5 5 3 AAA domain Sigma54_activ_2 PF14532.6 EKX38425.1 - 3e-11 43.6 0.1 0.00095 19.3 0.1 4.5 4 0 0 4 4 4 2 Sigma-54 interaction domain AAA_23 PF13476.6 EKX38425.1 - 3.6e-11 44.0 0.1 0.18 12.3 0.0 5.4 5 0 0 5 5 5 2 AAA domain DUF815 PF05673.13 EKX38425.1 - 7.5e-11 41.7 0.3 0.13 11.5 0.0 5.7 6 0 0 6 6 5 3 Protein of unknown function (DUF815) AAA_29 PF13555.6 EKX38425.1 - 8e-11 41.5 0.1 0.42 10.4 0.0 5.5 5 0 0 5 5 5 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EKX38425.1 - 1.3e-10 41.5 0.8 0.068 13.1 0.0 5.3 5 0 0 5 5 5 2 RsgA GTPase RNA_helicase PF00910.22 EKX38425.1 - 1.4e-10 41.5 1.3 0.4 11.1 0.0 5.5 5 0 0 5 5 5 2 RNA helicase AAA_25 PF13481.6 EKX38425.1 - 2.8e-10 40.1 2.8 0.48 10.0 0.0 5.0 5 0 0 5 5 4 3 AAA domain AAA_14 PF13173.6 EKX38425.1 - 3.4e-10 40.1 0.0 2.1 8.4 0.0 7.3 7 0 0 7 7 7 1 AAA domain Mg_chelatase PF01078.21 EKX38425.1 - 2e-09 37.1 2.0 1.8 7.9 0.0 7.8 7 1 0 7 7 7 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EKX38425.1 - 2e-09 37.9 7.0 0.34 11.2 0.0 5.7 5 0 0 5 5 5 1 AAA domain IstB_IS21 PF01695.17 EKX38425.1 - 5e-09 36.1 0.2 1.1 9.0 0.0 5.3 5 0 0 5 5 5 2 IstB-like ATP binding protein Roc PF08477.13 EKX38425.1 - 7.9e-09 35.8 1.4 0.95 9.7 0.0 5.4 5 0 0 5 5 5 1 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 EKX38425.1 - 8e-09 35.4 1.4 0.36 10.6 0.0 5.7 6 0 0 6 6 5 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 EKX38425.1 - 5e-08 33.0 6.0 0.41 10.6 0.1 5.8 6 0 0 6 6 5 2 NACHT domain Zeta_toxin PF06414.12 EKX38425.1 - 1.1e-07 31.3 4.0 1.9 7.7 0.0 6.2 7 0 0 7 7 5 1 Zeta toxin AAA_24 PF13479.6 EKX38425.1 - 5.3e-07 29.6 0.2 4.7 6.9 0.0 5.2 5 0 0 5 5 5 0 AAA domain AAA_19 PF13245.6 EKX38425.1 - 6.5e-07 29.8 5.0 0.21 11.9 0.1 5.6 6 0 0 6 6 4 1 AAA domain ATPase PF06745.13 EKX38425.1 - 1.2e-06 28.1 0.0 0.27 10.6 0.0 3.7 3 0 0 3 3 3 2 KaiC TniB PF05621.11 EKX38425.1 - 1.5e-06 27.7 0.6 0.27 10.6 0.0 5.4 6 0 0 6 6 5 1 Bacterial TniB protein Rad17 PF03215.15 EKX38425.1 - 2.1e-06 27.8 0.2 6.3 6.7 0.0 5.2 5 0 0 5 5 5 0 Rad17 P-loop domain SRP54 PF00448.22 EKX38425.1 - 9.1e-06 25.4 2.1 3.5 7.2 0.0 4.8 5 0 0 5 5 5 0 SRP54-type protein, GTPase domain CPT PF07931.12 EKX38425.1 - 1.6e-05 24.8 3.3 3.6 7.4 0.0 6.2 6 1 0 6 6 5 0 Chloramphenicol phosphotransferase-like protein TIP49 PF06068.13 EKX38425.1 - 2e-05 24.0 4.1 0.099 11.8 0.0 4.2 5 0 0 5 5 4 1 TIP49 P-loop domain ResIII PF04851.15 EKX38425.1 - 2.2e-05 24.5 0.1 0.44 10.5 0.0 3.8 4 0 0 4 4 3 2 Type III restriction enzyme, res subunit MMR_HSR1 PF01926.23 EKX38425.1 - 4.6e-05 23.5 3.3 11 6.1 0.0 5.7 6 0 0 6 6 5 0 50S ribosome-binding GTPase MCM PF00493.23 EKX38425.1 - 4.7e-05 22.6 0.1 0.12 11.4 0.0 4.0 3 1 1 4 4 4 1 MCM P-loop domain AAA_2 PF07724.14 EKX38425.1 - 5.9e-05 23.3 0.1 8.8 6.4 0.0 5.5 5 1 0 5 5 5 0 AAA domain (Cdc48 subfamily) NTPase_1 PF03266.15 EKX38425.1 - 0.00011 22.2 5.5 0.092 12.7 0.1 4.5 5 0 0 5 5 3 1 NTPase AAA_11 PF13086.6 EKX38425.1 - 0.00013 21.9 0.1 1.8 8.2 0.0 4.6 5 0 0 5 5 4 1 AAA domain PhoH PF02562.16 EKX38425.1 - 0.00014 21.4 0.3 0.89 9.0 0.0 3.8 4 0 0 4 4 4 1 PhoH-like protein Bac_DnaA PF00308.18 EKX38425.1 - 0.00018 21.4 0.1 15 5.3 0.0 4.6 4 0 0 4 4 4 0 Bacterial dnaA protein AAA_21 PF13304.6 EKX38425.1 - 0.0002 21.3 0.0 1.2 8.9 0.0 4.3 5 0 0 5 5 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_9 PF12781.7 EKX38425.1 - 0.00033 19.8 0.0 3.8 6.6 0.0 4.4 4 0 0 4 4 4 0 ATP-binding dynein motor region DAP3 PF10236.9 EKX38425.1 - 0.00062 19.0 0.2 4.2 6.4 0.0 3.4 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 DEAD PF00270.29 EKX38425.1 - 0.00086 19.1 0.1 1.1 9.1 0.0 3.7 3 1 0 3 3 3 1 DEAD/DEAH box helicase AAA_8 PF12780.7 EKX38425.1 - 0.0032 16.8 1.8 2.4 7.4 0.0 4.8 6 0 0 6 6 6 1 P-loop containing dynein motor region D4 cobW PF02492.19 EKX38425.1 - 0.0042 16.7 5.8 1.7 8.2 0.2 4.7 5 0 0 5 5 5 1 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.25 EKX38425.1 - 0.0048 16.6 0.0 2.3 7.8 0.0 3.8 4 0 0 4 4 4 1 ATP synthase alpha/beta family, nucleotide-binding domain Cytidylate_kin PF02224.18 EKX38425.1 - 0.0071 16.1 2.8 17 5.0 0.1 4.7 4 0 0 4 4 4 0 Cytidylate kinase PIF1 PF05970.14 EKX38425.1 - 0.0081 15.4 0.0 0.56 9.3 0.0 3.0 3 0 0 3 3 2 1 PIF1-like helicase DnaB_C PF03796.15 EKX38425.1 - 0.01 15.2 0.4 1.8 7.8 0.0 3.5 4 0 0 4 4 3 0 DnaB-like helicase C terminal domain ATP_bind_1 PF03029.17 EKX38425.1 - 0.014 15.2 8.9 11 5.7 0.2 5.0 5 0 0 5 5 4 0 Conserved hypothetical ATP binding protein DUF853 PF05872.12 EKX38425.1 - 0.016 13.8 0.5 1.7 7.2 0.1 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Guanylate_kin PF00625.21 EKX38425.1 - 0.032 13.9 1.0 37 3.9 0.0 4.6 5 0 0 5 5 5 0 Guanylate kinase SRPRB PF09439.10 EKX38425.1 - 0.042 13.3 2.2 39 3.6 0.0 4.7 5 0 0 5 5 5 0 Signal recognition particle receptor beta subunit CbiA PF01656.23 EKX38425.1 - 0.1 12.6 2.4 32 4.6 0.2 4.2 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain dNK PF01712.19 EKX38425.1 - 0.12 12.2 6.1 33 4.3 0.0 4.8 5 0 0 5 5 4 0 Deoxynucleoside kinase Ras PF00071.22 EKX38425.1 - 0.12 11.9 1.5 56 3.3 0.0 4.0 4 0 0 4 4 4 0 Ras family DUF927 PF06048.11 EKX38425.1 - 0.12 11.9 0.3 0.76 9.3 0.1 2.4 2 0 0 2 2 1 0 Domain of unknown function (DUF927) Gtr1_RagA PF04670.12 EKX38425.1 - 0.15 11.4 1.9 41 3.4 0.0 4.1 5 0 0 5 5 4 0 Gtr1/RagA G protein conserved region Septin PF00735.18 EKX38425.1 - 0.16 11.2 1.1 33 3.6 0.0 4.0 5 0 0 5 5 4 0 Septin Viral_helicase1 PF01443.18 EKX38425.1 - 0.2 11.3 0.6 57 3.3 0.0 3.9 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase FtsK_SpoIIIE PF01580.18 EKX38425.1 - 0.33 10.2 1.8 49 3.1 0.0 3.8 4 0 0 4 4 4 0 FtsK/SpoIIIE family PRK PF00485.18 EKX38425.1 - 0.36 10.6 3.2 20 4.9 0.0 3.9 4 0 0 4 4 3 0 Phosphoribulokinase / Uridine kinase family TrwB_AAD_bind PF10412.9 EKX38425.1 - 0.64 8.9 2.8 34 3.2 0.1 3.7 3 1 1 4 4 4 0 Type IV secretion-system coupling protein DNA-binding domain UvrD-helicase PF00580.21 EKX38425.1 - 1 8.8 3.0 83 2.5 0.0 4.1 4 0 0 4 4 4 0 UvrD/REP helicase N-terminal domain FHA PF00498.26 EKX38426.1 - 7.7e-13 48.6 0.1 4.5e-12 46.1 0.0 2.3 2 0 0 2 2 2 1 FHA domain C2 PF00168.30 EKX38427.1 - 1.1e-28 99.6 0.1 1.3e-28 99.3 0.1 1.1 1 0 0 1 1 1 1 C2 domain TSP_1 PF00090.19 EKX38427.1 - 0.0064 16.7 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Thrombospondin type 1 domain WD40 PF00400.32 EKX38428.1 - 5.2e-13 49.3 12.6 3.6e-06 27.6 2.7 3.7 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX38428.1 - 0.00076 19.7 0.1 0.41 11.0 0.1 2.8 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_1 PF00036.32 EKX38429.1 - 2.3e-17 61.2 1.4 2.5e-05 23.5 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EKX38429.1 - 1e-15 57.9 1.0 1.4e-09 38.2 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX38429.1 - 4.8e-14 51.0 1.3 4.3e-05 23.1 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_9 PF14658.6 EKX38429.1 - 4.1e-10 39.8 0.1 1.1e-05 25.7 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EKX38429.1 - 1.7e-09 37.4 0.7 1.7e-09 37.4 0.7 3.4 3 2 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX38429.1 - 3.2e-05 23.2 1.1 0.0013 18.1 0.0 3.1 3 0 0 3 3 3 1 EF hand EF-hand_4 PF12763.7 EKX38429.1 - 0.00015 21.7 0.2 0.0047 16.9 0.0 2.5 2 2 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EKX38429.1 - 0.00081 19.7 0.2 0.004 17.4 0.1 1.9 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Toprim_2 PF13155.6 EKX38429.1 - 0.0054 17.1 0.0 1.6 9.2 0.0 2.2 1 1 1 2 2 2 2 Toprim-like p25-alpha PF05517.12 EKX38429.1 - 0.011 15.9 0.1 0.018 15.2 0.1 1.5 1 1 0 1 1 1 0 p25-alpha DUF1398 PF07166.11 EKX38429.1 - 0.17 11.9 0.1 0.71 9.9 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1398) RE_HaeII PF09554.10 EKX38431.1 - 0.069 12.4 0.1 1.4 8.1 0.0 2.2 2 0 0 2 2 2 0 HaeII restriction endonuclease Transket_pyr PF02779.24 EKX38432.1 - 4.9e-68 228.3 1.2 1.1e-67 227.1 0.0 2.0 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 EKX38432.1 - 2e-58 197.7 0.0 3.1e-58 197.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 EKX38432.1 - 7.4e-50 168.6 0.0 1.3e-49 167.8 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 EKX38432.1 - 1.9e-16 59.3 0.2 3.8e-16 58.4 0.2 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus Complex1_LYR PF05347.15 EKX38432.1 - 2.4 8.2 4.1 25 5.0 0.1 3.5 3 0 0 3 3 3 0 Complex 1 protein (LYR family) SGTA_dimer PF16546.5 EKX38433.1 - 5.4e-16 58.1 0.0 1.1e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 EKX38433.1 - 1.8e-15 56.0 5.8 2.7e-09 36.4 0.2 4.2 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX38433.1 - 2.1e-11 43.3 10.5 5e-06 26.1 0.8 3.9 3 1 1 4 4 4 2 TPR repeat TPR_2 PF07719.17 EKX38433.1 - 6.5e-08 32.1 11.5 3.4e-05 23.6 0.1 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX38433.1 - 9.5e-06 26.0 8.4 0.16 12.9 0.1 5.3 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX38433.1 - 8.1e-05 22.5 5.6 0.0042 17.2 0.1 4.8 6 0 0 6 6 5 1 Tetratricopeptide repeat SGT1 PF07093.11 EKX38433.1 - 0.00027 19.5 0.2 0.00039 19.0 0.2 1.2 1 0 0 1 1 1 1 SGT1 protein TPR_17 PF13431.6 EKX38433.1 - 0.00032 20.9 4.6 0.02 15.3 0.7 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX38433.1 - 0.00037 20.7 5.4 0.0005 20.3 1.3 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX38433.1 - 0.00071 20.2 6.6 0.0074 16.9 0.1 4.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX38433.1 - 0.0023 18.4 0.2 0.0023 18.4 0.2 3.2 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX38433.1 - 0.0036 17.1 2.2 0.24 11.3 0.2 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX38433.1 - 0.0038 17.3 0.1 0.0038 17.3 0.1 2.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TENA_THI-4 PF03070.16 EKX38433.1 - 0.044 13.6 1.2 0.076 12.8 1.2 1.4 1 0 0 1 1 1 0 TENA/THI-4/PQQC family Fis1_TPR_C PF14853.6 EKX38433.1 - 0.2 11.8 1.6 3 8.0 0.2 3.0 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 EKX38433.1 - 0.53 10.5 5.9 2.7 8.3 1.7 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 EKX38433.1 - 2.4 8.3 10.6 2.5 8.3 0.1 4.6 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain RWP-RK PF02042.15 EKX38434.1 - 1.3e-12 47.5 0.2 1.9e-12 46.9 0.2 1.3 1 0 0 1 1 1 1 RWP-RK domain TPR_12 PF13424.6 EKX38435.1 - 1.7e-11 44.2 7.7 1.3e-06 28.6 0.9 1.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX38435.1 - 3e-06 26.9 1.5 3.2e-05 23.7 0.4 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX38435.1 - 0.00087 19.2 0.6 0.0032 17.5 0.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX38435.1 - 0.02 14.7 0.2 0.12 12.3 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Ubiquitin_5 PF18037.1 EKX38435.1 - 0.027 14.8 0.0 0.035 14.4 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-like domain TPR_4 PF07721.14 EKX38435.1 - 0.069 13.8 0.8 0.069 13.8 0.8 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Keratin_2_head PF16208.5 EKX38436.1 - 0.14 12.3 26.5 0.27 11.4 26.5 1.4 1 0 0 1 1 1 0 Keratin type II head BslA PF17735.1 EKX38437.1 - 0.0004 20.4 4.7 0.074 13.0 0.1 5.0 5 0 0 5 5 5 1 Biofilm surface layer A fn2 PF00040.19 EKX38437.1 - 0.011 16.0 0.5 0.03 14.6 0.5 1.8 1 0 0 1 1 1 0 Fibronectin type II domain DUF2808 PF10989.8 EKX38437.1 - 0.013 15.4 2.2 7 6.6 0.0 6.2 8 0 0 8 8 8 0 Protein of unknown function (DUF2808) Methyltranf_PUA PF13636.6 EKX38437.1 - 0.016 15.2 0.0 0.19 11.7 0.0 2.5 2 0 0 2 2 2 0 RNA-binding PUA-like domain of methyltransferase RsmF Polyketide_cyc2 PF10604.9 EKX38438.1 - 0.024 14.9 0.1 0.065 13.5 0.1 1.7 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport KH_8 PF17903.1 EKX38439.1 - 0.015 15.4 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 Krr1 KH1 domain KH_1 PF00013.29 EKX38439.1 - 0.058 13.2 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 KH domain DPM2 PF07297.12 EKX38440.1 - 6.9e-22 77.6 6.7 7.4e-22 77.4 6.7 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 EKX38440.1 - 0.00077 19.4 6.6 0.00099 19.0 6.6 1.1 1 0 0 1 1 1 1 PIG-P Xpo1 PF08389.12 EKX38442.1 - 7.1e-30 104.0 3.4 4.6e-29 101.4 0.1 3.7 4 0 0 4 4 4 1 Exportin 1-like protein Dopey_N PF04118.14 EKX38442.1 - 0.028 13.5 1.6 0.081 12.0 0.2 2.2 2 0 0 2 2 2 0 Dopey, N-terminal CLASP_N PF12348.8 EKX38442.1 - 0.034 13.7 11.0 0.25 10.9 0.1 4.0 3 1 0 3 3 3 0 CLASP N terminal DnaJ PF00226.31 EKX38443.1 - 4.4e-24 84.4 0.6 4.9e-24 84.2 0.6 1.0 1 0 0 1 1 1 1 DnaJ domain SRR PF07709.11 EKX38443.1 - 0.076 13.4 0.1 14 6.6 0.1 2.7 2 0 0 2 2 2 0 Seven Residue Repeat BCA_ABC_TP_C PF12399.8 EKX38443.1 - 0.16 11.9 2.3 0.61 10.1 0.0 2.6 3 0 0 3 3 3 0 Branched-chain amino acid ATP-binding cassette transporter PAS_9 PF13426.7 EKX38444.1 - 2.5e-07 30.9 0.0 2.8e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 PAS domain Ribosomal_S8 PF00410.19 EKX38445.1 - 0.21 11.5 0.0 1 9.4 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S8 Pkinase PF00069.25 EKX38446.1 - 9.3e-58 195.7 0.0 1.3e-57 195.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX38446.1 - 3.9e-36 124.7 0.0 5.5e-36 124.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX38446.1 - 0.0035 16.2 0.0 0.0092 14.8 0.0 1.7 1 1 1 2 2 2 1 Fungal protein kinase APH PF01636.23 EKX38446.1 - 0.016 15.1 1.4 0.072 13.0 0.2 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EKX38446.1 - 0.024 14.0 0.1 0.052 12.9 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family HATPase_c PF02518.26 EKX38447.1 - 1.7e-27 96.1 0.0 2.5e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EKX38447.1 - 1.5e-14 53.8 0.4 2.4e-14 53.1 0.4 1.3 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 EKX38447.1 - 0.00021 21.2 0.0 0.00033 20.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain PDZ_6 PF17820.1 EKX38448.1 - 6.4e-08 32.3 0.1 2e-07 30.7 0.1 1.9 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX38448.1 - 1.4e-05 25.3 0.0 4.5e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX38448.1 - 0.00012 22.3 0.2 0.00081 19.7 0.0 2.5 3 0 0 3 3 3 1 PDZ domain SH3_2 PF07653.17 EKX38448.1 - 0.00015 21.3 0.0 0.00051 19.7 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain PDZ_4 PF17816.1 EKX38448.1 - 0.023 15.1 0.6 0.13 12.7 0.0 2.6 2 0 0 2 2 2 0 PDZ domain PfkB PF00294.24 EKX38448.1 - 1.7 7.9 6.6 0.08 12.2 0.7 1.7 2 0 0 2 2 2 0 pfkB family carbohydrate kinase CitMHS PF03600.16 EKX38449.1 - 1e-43 149.7 0.0 3.4e-43 148.0 0.0 1.8 1 1 1 2 2 2 2 Citrate transporter Na_sulph_symp PF00939.19 EKX38449.1 - 2.1e-15 56.8 27.9 5.9e-13 48.7 15.3 2.2 2 0 0 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS_2 PF16980.5 EKX38449.1 - 1.9e-05 23.6 0.6 1.9e-05 23.6 0.6 1.9 2 0 0 2 2 2 1 Putative citrate transport TrkA_C PF02080.21 EKX38449.1 - 0.0026 17.5 0.0 4 7.3 0.0 3.8 4 0 0 4 4 4 2 TrkA-C domain Ribosomal_S21 PF01165.20 EKX38450.1 - 1.1e-14 53.9 5.6 1.4e-14 53.5 5.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S21 PorA PF11271.8 EKX38451.1 - 0.035 13.4 0.0 0.06 12.6 0.0 1.3 1 1 0 1 1 1 0 Porin PorA Ribosomal_S5_C PF03719.15 EKX38452.1 - 4.1e-18 64.6 0.1 7e-18 63.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 EKX38452.1 - 7.1e-17 61.2 2.7 1.6e-16 60.0 2.6 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain COX6C PF02937.15 EKX38452.1 - 0.088 12.9 0.4 0.17 12.1 0.4 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc COX6C PF02937.15 EKX38453.1 - 9.5 6.4 5.7 2.9 8.1 1.3 2.4 4 0 0 4 4 4 0 Cytochrome c oxidase subunit VIc PDZ_6 PF17820.1 EKX38454.1 - 1.2e-11 44.2 0.0 2.6e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX38454.1 - 1.8e-10 41.0 0.1 4e-10 39.9 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX38454.1 - 2.7e-06 27.6 0.1 6.9e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX38454.1 - 0.032 14.2 0.0 0.076 13.0 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain RRM_1 PF00076.22 EKX38457.1 - 6.1e-20 70.8 0.0 6.9e-20 70.6 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EKX38457.1 - 6e-06 26.3 0.0 8.1e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 EKX38457.1 - 0.0016 18.0 0.0 0.0018 17.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dicty_CAR PF05462.11 EKX38457.1 - 0.12 11.5 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor PPR_long PF17177.4 EKX38458.1 - 4.1e-06 26.3 0.1 1.2e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP Pox_EPC_I2-L1 PF12575.8 EKX38458.1 - 0.011 16.0 0.2 0.028 14.7 0.2 1.6 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 MMS19_N PF14500.6 EKX38458.1 - 0.031 13.8 0.1 0.06 12.9 0.0 1.4 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II PPR_2 PF13041.6 EKX38458.1 - 0.26 11.5 0.0 0.26 11.5 0.0 2.7 4 0 0 4 4 4 0 PPR repeat family PRORP PF16953.5 EKX38459.1 - 2.7e-18 66.4 1.7 6.5e-17 61.9 1.7 2.6 1 1 0 1 1 1 1 Protein-only RNase P RNase_Zc3h12a PF11977.8 EKX38459.1 - 1.3e-07 31.5 0.1 3.1e-07 30.3 0.1 1.6 1 1 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain TPR_1 PF00515.28 EKX38460.1 - 0.045 13.6 0.2 0.094 12.6 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat PPR_2 PF13041.6 EKX38460.1 - 0.13 12.4 0.3 2.7 8.3 0.5 2.9 2 1 1 3 3 3 0 PPR repeat family PPR PF01535.20 EKX38460.1 - 0.58 10.5 6.2 1.4 9.3 1.1 3.9 4 0 0 4 4 4 0 PPR repeat ERO1 PF04137.15 EKX38461.1 - 6.2e-30 104.6 2.8 7.2e-23 81.3 0.2 2.0 1 1 1 2 2 2 2 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Adenylsucc_synt PF00709.21 EKX38465.1 - 2.1e-108 363.0 0.2 2.5e-108 362.7 0.2 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Ribosomal_S5 PF00333.20 EKX38468.1 - 0.033 14.2 0.2 0.095 12.7 0.1 1.9 2 1 0 2 2 2 0 Ribosomal protein S5, N-terminal domain Phage_Coat_B PF05356.11 EKX38468.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Phage Coat protein B EGL-1 PF11430.8 EKX38471.1 - 0.94 9.4 2.5 0.81 9.6 0.7 1.8 2 0 0 2 2 2 0 Programmed cell death activator EGL-1 Drf_GBD PF06371.13 EKX38473.1 - 0.03 13.9 0.3 0.03 13.9 0.3 1.7 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain gpW PF02831.15 EKX38474.1 - 0.088 12.7 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 gpW Laminin_G_3 PF13385.6 EKX38475.1 - 3.4e-09 37.0 0.6 6.2e-09 36.2 0.2 1.6 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 EKX38475.1 - 0.0046 17.5 0.1 0.0077 16.8 0.1 1.5 1 1 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 EKX38475.1 - 0.029 14.6 0.0 0.044 14.0 0.0 1.5 1 1 0 1 1 1 0 Laminin G domain zf-NOSIP PF15906.5 EKX38476.1 - 0.01 16.0 0.2 0.26 11.4 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger of nitric oxide synthase-interacting protein AAA_11 PF13086.6 EKX38477.1 - 0.00028 20.8 0.0 0.00052 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EKX38477.1 - 0.028 14.8 0.0 0.061 13.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EKX38477.1 - 0.068 13.4 0.0 0.19 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EKX38477.1 - 0.071 13.5 0.0 0.21 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 EKX38477.1 - 0.089 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EKX38477.1 - 0.11 12.1 0.1 0.42 10.2 0.0 1.9 2 1 1 3 3 3 0 AAA domain CbiA PF01656.23 EKX38477.1 - 0.2 11.7 0.0 0.49 10.5 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 EKX38477.1 - 0.35 11.4 2.8 2.4 8.7 2.8 2.2 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EKX38478.1 - 0.00015 21.7 0.5 0.00042 20.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EKX38478.1 - 0.02 15.3 0.0 0.049 14.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EKX38478.1 - 0.037 14.3 0.0 0.14 12.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EKX38478.1 - 0.081 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EKX38478.1 - 0.082 13.3 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 EKX38478.1 - 0.085 12.4 0.1 0.34 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 EKX38478.1 - 0.14 12.2 0.0 0.57 10.2 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit CbiA PF01656.23 EKX38478.1 - 0.18 11.9 0.0 0.41 10.7 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.7 EKX38478.1 - 0.2 11.1 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 EKX38478.1 - 0.88 10.1 3.4 1.2 9.7 0.9 2.5 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EKX38479.1 - 0.00014 21.7 2.0 0.00042 20.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EKX38479.1 - 0.019 15.4 0.0 0.052 14.0 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EKX38479.1 - 0.031 14.5 0.0 0.16 12.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EKX38479.1 - 0.042 14.2 0.1 0.13 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 EKX38479.1 - 0.066 12.9 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EKX38479.1 - 0.077 12.6 0.1 0.34 10.5 0.0 2.0 2 1 1 3 3 3 0 AAA domain AAA_7 PF12775.7 EKX38479.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region CbiA PF01656.23 EKX38479.1 - 0.16 12.0 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ResIII PF04851.15 EKX38479.1 - 0.17 11.9 0.2 0.55 10.2 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 EKX38479.1 - 0.53 10.8 5.1 0.71 10.4 2.5 2.5 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EKX38480.1 - 0.00025 20.9 0.4 0.00051 19.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EKX38480.1 - 0.037 14.4 0.0 0.089 13.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EKX38480.1 - 0.055 13.7 0.0 0.2 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EKX38480.1 - 0.099 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EKX38480.1 - 0.1 12.2 0.0 0.41 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EKX38480.1 - 0.12 12.8 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain CbiA PF01656.23 EKX38480.1 - 0.2 11.7 0.0 0.46 10.5 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.7 EKX38480.1 - 0.21 11.1 0.0 0.37 10.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 EKX38481.1 - 0.0002 21.3 1.0 0.00052 19.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EKX38481.1 - 0.036 14.5 0.0 0.088 13.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EKX38481.1 - 0.055 13.7 0.0 0.18 12.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EKX38481.1 - 0.09 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EKX38481.1 - 0.094 12.3 0.1 0.42 10.2 0.0 2.1 2 1 1 3 3 3 0 AAA domain AAA_16 PF13191.6 EKX38481.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain CbiA PF01656.23 EKX38481.1 - 0.19 11.8 0.0 0.43 10.6 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.7 EKX38481.1 - 0.21 11.1 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 EKX38481.1 - 4.4 7.9 6.9 2.6 8.6 3.2 2.4 2 1 0 2 2 2 0 AAA domain RWP-RK PF02042.15 EKX38482.1 - 4.5e-14 52.1 0.0 8.4e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain Vps5 PF09325.10 EKX38484.1 - 0.024 14.2 2.4 0.03 13.9 2.4 1.2 1 0 0 1 1 1 0 Vps5 C terminal like EPO_TPO PF00758.18 EKX38484.1 - 0.027 14.5 0.1 0.03 14.4 0.1 1.2 1 0 0 1 1 1 0 Erythropoietin/thrombopoietin BAG6 PF12057.8 EKX38484.1 - 0.031 13.9 2.8 0.079 12.6 0.0 2.0 2 0 0 2 2 2 0 BCL2-associated athanogene 6 V_ATPase_I PF01496.19 EKX38484.1 - 0.15 9.9 2.9 0.18 9.7 2.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NicO PF03824.16 EKX38484.1 - 0.27 10.5 1.8 0.34 10.2 1.8 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein Sox_N PF12444.8 EKX38484.1 - 7.4 7.8 8.1 0.48 11.6 2.0 1.9 1 1 1 2 2 2 0 Sox developmental protein N terminal DUF5532 PF17673.1 EKX38485.1 - 0.061 13.4 0.1 0.2 11.8 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5532) ddrB-ParB PF18763.1 EKX38485.1 - 0.079 13.1 0.4 0.31 11.2 0.1 2.0 1 1 0 2 2 2 0 ddrB-like ParB superfamily domain FlxA PF14282.6 EKX38486.1 - 0.47 10.5 8.8 0.11 12.5 4.7 2.0 2 0 0 2 2 2 0 FlxA-like protein PDZ PF00595.24 EKX38487.1 - 8.3e-24 83.8 1.8 2.5e-06 27.7 0.0 3.4 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 EKX38487.1 - 8.4e-23 80.0 4.5 2e-06 27.6 0.2 3.5 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 EKX38487.1 - 1.6e-20 73.2 0.5 1.8e-06 28.2 0.0 3.3 3 0 0 3 3 3 3 PDZ domain Tricorn_PDZ PF14685.6 EKX38487.1 - 0.00068 19.5 1.2 4.3 7.4 0.0 3.4 3 0 0 3 3 3 2 Tricorn protease PDZ domain DUF3394 PF11874.8 EKX38487.1 - 0.14 11.8 0.0 1.5 8.4 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3394) Mucin-like PF16058.5 EKX38487.1 - 2.5 8.3 8.1 0.12 12.5 1.8 1.9 2 0 0 2 2 2 0 Mucin-like S-AdoMet_synt_C PF02773.16 EKX38488.1 - 2.1e-68 228.6 0.0 3.4e-68 227.9 0.0 1.3 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_N PF00438.20 EKX38488.1 - 4e-42 142.9 0.4 8e-42 142.0 0.4 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.16 EKX38488.1 - 1.5e-41 141.4 0.0 2.8e-41 140.5 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain YibE_F PF07907.11 EKX38491.1 - 0.02 14.4 3.6 0.022 14.3 3.6 1.0 1 0 0 1 1 1 0 YibE/F-like protein DUF5385 PF17359.2 EKX38491.1 - 0.34 10.5 1.6 0.36 10.3 1.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) TPR_17 PF13431.6 EKX38492.1 - 3.1e-24 83.6 22.4 0.0068 16.7 0.1 13.0 13 1 0 13 13 13 5 Tetratricopeptide repeat TPR_14 PF13428.6 EKX38492.1 - 1.5e-18 65.9 40.6 0.03 15.1 0.1 13.9 4 4 11 15 15 15 5 Tetratricopeptide repeat TPR_16 PF13432.6 EKX38492.1 - 2.7e-15 56.7 35.7 0.00029 21.4 3.8 7.9 8 2 1 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 EKX38492.1 - 1.6e-14 54.1 36.2 0.0013 19.2 0.7 10.0 8 3 2 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX38492.1 - 2.6e-11 42.8 30.0 0.41 11.0 0.1 12.1 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_2 PF07719.17 EKX38492.1 - 1.1e-09 37.7 45.5 2.1 8.7 0.4 13.7 14 0 0 14 14 14 5 Tetratricopeptide repeat TPR_11 PF13414.6 EKX38492.1 - 4.4e-08 32.7 27.8 0.11 12.2 0.1 10.2 12 0 0 12 12 12 3 TPR repeat TPR_1 PF00515.28 EKX38492.1 - 1.8e-05 24.3 46.6 2.1 8.3 1.1 13.5 15 0 0 15 15 15 3 Tetratricopeptide repeat TPR_6 PF13174.6 EKX38492.1 - 0.00013 22.4 25.8 2.4 9.0 0.2 10.0 10 1 1 11 11 10 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX38492.1 - 0.00077 19.7 27.5 0.17 12.2 0.5 8.1 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX38492.1 - 0.002 18.0 19.4 14 5.9 0.0 9.5 10 0 0 10 10 9 0 Tetratricopeptide repeat Phage_pRha PF09669.10 EKX38492.1 - 0.049 14.2 0.1 0.18 12.4 0.1 2.1 1 0 0 1 1 1 0 Phage regulatory protein Rha (Phage_pRha) DUF4366 PF14283.6 EKX38492.1 - 0.065 13.3 0.2 0.065 13.3 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) ANAPC3 PF12895.7 EKX38492.1 - 0.34 11.1 20.9 0.72 10.1 0.2 5.7 4 1 2 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 TT_ORF1 PF02956.14 EKX38492.1 - 1.7 7.3 12.4 3.5 6.2 12.4 1.5 1 0 0 1 1 1 0 TT viral orf 1 SBP_bac_3 PF00497.20 EKX38495.1 - 2.7e-09 36.8 0.0 1.2e-08 34.7 0.0 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Ion_trans_2 PF07885.16 EKX38495.1 - 4.2e-07 29.8 1.9 4.7e-07 29.7 0.5 1.9 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 EKX38495.1 - 9.1e-05 21.8 0.3 0.00036 19.8 0.2 1.8 2 0 0 2 2 2 1 Ion transport protein Lig_chan-Glu_bd PF10613.9 EKX38495.1 - 0.013 15.7 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site DUF2153 PF09921.9 EKX38495.1 - 0.042 13.7 0.0 0.077 12.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) TFIIS_C PF01096.18 EKX38496.1 - 2.8e-19 68.7 2.2 4.4e-19 68.0 2.2 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EKX38496.1 - 0.0017 18.1 2.3 0.01 15.7 2.3 2.0 1 1 0 1 1 1 1 RNA polymerases M/15 Kd subunit Zn-ribbon_8 PF09723.10 EKX38496.1 - 0.0018 18.3 0.8 1.1 9.5 0.1 2.5 2 0 0 2 2 2 2 Zinc ribbon domain Terminase_GpA PF05876.12 EKX38496.1 - 0.004 15.8 0.1 0.0047 15.5 0.1 1.0 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) zf-TFIIB PF13453.6 EKX38496.1 - 0.0067 15.7 0.7 0.014 14.7 0.7 1.5 1 0 0 1 1 1 1 Transcription factor zinc-finger DUF2387 PF09526.10 EKX38496.1 - 0.0087 16.2 0.9 0.013 15.6 0.9 1.3 1 0 0 1 1 1 1 Probable metal-binding protein (DUF2387) Zn_Tnp_IS1595 PF12760.7 EKX38496.1 - 0.013 15.5 0.7 0.025 14.6 0.7 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Baculo_LEF5_C PF11792.8 EKX38496.1 - 0.02 14.6 3.4 0.024 14.3 0.1 2.2 1 1 1 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain tRNA-synt_1f PF01921.18 EKX38496.1 - 0.021 13.7 0.1 0.021 13.7 0.1 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (K) zinc_ribbon_4 PF13717.6 EKX38496.1 - 0.033 14.1 3.7 0.25 11.3 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Ogr_Delta PF04606.12 EKX38496.1 - 0.037 14.0 1.9 0.074 13.0 1.9 1.5 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger A2L_zn_ribbon PF08792.10 EKX38496.1 - 0.074 12.8 2.3 5.8 6.8 0.1 2.5 2 0 0 2 2 2 0 A2L zinc ribbon domain zinc_ribbon_10 PF10058.9 EKX38496.1 - 0.1 12.3 2.0 0.24 11.1 2.1 1.6 1 1 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Mut7-C PF01927.16 EKX38496.1 - 0.11 12.6 1.6 0.14 12.2 1.6 1.2 1 0 0 1 1 1 0 Mut7-C RNAse domain zf-ribbon_3 PF13248.6 EKX38496.1 - 0.15 11.5 3.6 3.6 7.1 0.6 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_13 PF09855.9 EKX38496.1 - 0.2 11.9 3.9 7.1 6.9 4.0 2.2 1 1 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) VP_N-CPKC PF11475.8 EKX38496.1 - 0.26 11.2 4.0 9.8 6.2 1.5 2.9 2 1 0 2 2 2 0 Virion protein N terminal domain DUF4379 PF14311.6 EKX38496.1 - 0.6 10.5 5.6 0.51 10.8 0.4 2.2 1 1 0 2 2 2 0 Probable Zinc-ribbon domain zf_C2H2_10 PF18414.1 EKX38496.1 - 0.96 9.0 0.0 0.96 9.0 0.0 2.6 3 0 0 3 3 3 0 C2H2 type zinc-finger UPF0547 PF10571.9 EKX38496.1 - 1.1 9.4 6.8 0.79 9.9 0.7 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Amido_AtzD_TrzD PF09663.10 EKX38498.1 - 0.041 12.9 0.1 0.044 12.8 0.1 1.0 1 0 0 1 1 1 0 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) DAGK_cat PF00781.24 EKX38500.1 - 2.9e-23 81.9 0.0 4.5e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Herpes_glycop PF01528.16 EKX38501.1 - 0.0083 15.0 4.2 0.0099 14.8 4.2 1.1 1 0 0 1 1 1 1 Herpesvirus glycoprotein M PalH PF08733.10 EKX38501.1 - 2.3 7.1 10.3 23 3.8 11.6 1.5 1 1 0 1 1 1 0 PalH/RIM21 DUF2070 PF09843.9 EKX38501.1 - 2.4 6.3 5.6 2.9 6.1 5.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Phage_holin_3_6 PF07332.11 EKX38501.1 - 8.3 6.5 12.3 94 3.1 12.3 2.0 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Zn_clus PF00172.18 EKX38502.1 - 1.1e-07 31.8 11.2 2.4e-07 30.8 11.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank PF00023.30 EKX38502.1 - 0.072 13.6 0.9 0.87 10.1 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat Adaptin_N PF01602.20 EKX38503.1 - 5.1e-147 490.6 6.1 6.2e-147 490.3 6.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EKX38503.1 - 2.1e-63 213.2 3.7 1.8e-61 206.9 0.2 2.9 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EKX38503.1 - 2.5e-16 59.8 1.2 3.4e-05 24.1 0.0 6.2 4 2 2 6 6 6 3 HEAT repeats HEAT PF02985.22 EKX38503.1 - 1.9e-09 36.9 8.6 0.0036 17.4 0.0 6.8 7 1 0 8 8 6 2 HEAT repeat Cnd3 PF12719.7 EKX38503.1 - 1.8e-05 24.1 1.0 0.00063 19.0 0.2 2.7 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain Arm PF00514.23 EKX38503.1 - 3.2e-05 23.8 1.2 0.1 12.6 0.0 5.4 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat B2-adapt-app_C PF09066.10 EKX38503.1 - 7.2e-05 22.8 0.0 0.00017 21.7 0.0 1.7 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain CLASP_N PF12348.8 EKX38503.1 - 0.0015 18.1 0.3 0.67 9.5 0.0 3.1 3 0 0 3 3 3 1 CLASP N terminal HEAT_EZ PF13513.6 EKX38503.1 - 0.0084 16.6 6.7 0.87 10.2 0.1 5.7 6 1 1 7 7 6 1 HEAT-like repeat Arm_2 PF04826.13 EKX38503.1 - 0.019 14.5 0.4 0.19 11.1 0.0 2.6 1 1 1 2 2 2 0 Armadillo-like UNC45-central PF11701.8 EKX38503.1 - 0.023 14.7 0.1 2.7 7.9 0.0 3.6 2 1 0 3 3 3 0 Myosin-binding striated muscle assembly central FadR_C PF07840.12 EKX38503.1 - 0.038 13.9 0.5 36 4.2 0.0 3.6 4 0 0 4 4 4 0 FadR C-terminal domain DUF5578 PF17741.1 EKX38503.1 - 0.12 11.8 1.6 0.99 8.8 0.0 3.0 3 1 0 3 3 3 0 Family of unknown function (DUF5578) Anoctamin PF04547.12 EKX38504.1 - 1.9e-29 102.8 3.3 2.5e-29 102.4 3.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Morc6_S5 PF17942.1 EKX38505.1 - 5.9e-14 52.3 0.0 1.1e-13 51.4 0.0 1.4 1 0 0 1 1 1 1 Morc6 ribosomal protein S5 domain 2-like HATPase_c_3 PF13589.6 EKX38505.1 - 7.1e-11 42.1 0.2 1.9e-10 40.7 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PWWP PF00855.17 EKX38505.1 - 1.4e-08 35.0 0.2 3.4e-08 33.8 0.2 1.7 1 0 0 1 1 1 1 PWWP domain Pkinase_Tyr PF07714.17 EKX38505.1 - 6.7e-06 25.6 1.2 8.8e-06 25.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EKX38505.1 - 0.0012 18.3 0.0 0.0028 17.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain zf-CW PF07496.15 EKX38505.1 - 0.0057 16.7 0.7 0.021 14.9 0.7 2.0 1 0 0 1 1 1 1 CW-type Zinc Finger HATPase_c PF02518.26 EKX38505.1 - 0.0057 17.1 0.1 0.014 15.9 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GDA1_CD39 PF01150.17 EKX38506.1 - 6.7e-76 255.6 0.0 9.5e-76 255.1 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Integrase_Zn PF02022.19 EKX38506.1 - 0.18 11.8 0.0 0.46 10.5 0.0 1.7 1 0 0 1 1 1 0 Integrase Zinc binding domain Tom7 PF08038.12 EKX38508.1 - 2.7e-14 52.5 0.1 3.8e-14 52.1 0.1 1.2 1 0 0 1 1 1 1 TOM7 family PDZ PF00595.24 EKX38509.1 - 1.1e-09 38.4 0.0 2.1e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX38509.1 - 1.4e-09 37.6 0.1 2.4e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX38509.1 - 0.0056 17.0 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain DUF2070 PF09843.9 EKX38511.1 - 0.12 10.6 4.5 0.16 10.2 4.5 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Beta_helix PF13229.6 EKX38513.1 - 4.1e-44 150.2 31.2 5.6e-14 52.3 0.6 5.1 1 1 2 4 4 4 4 Right handed beta helix region NosD PF05048.13 EKX38513.1 - 3.6e-43 147.6 52.2 9.9e-16 57.7 4.8 5.2 1 1 5 6 6 6 6 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.11 EKX38513.1 - 5.4e-09 35.8 13.3 7.2e-06 25.5 5.9 5.0 2 1 4 6 6 6 3 Protein of unknown function (DUF1565) TPR_1 PF00515.28 EKX38515.1 - 1.6e-15 56.1 2.3 6.7e-08 32.0 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX38515.1 - 4.8e-14 51.8 8.6 1.5e-07 31.0 0.1 3.0 1 1 2 3 3 3 2 TPR repeat TPR_2 PF07719.17 EKX38515.1 - 1.4e-13 49.8 1.0 3.7e-06 26.6 0.0 2.4 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX38515.1 - 2.7e-13 49.0 3.2 1.2e-05 25.1 0.1 2.4 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX38515.1 - 9.6e-13 48.2 3.1 3.7e-06 27.1 0.1 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX38515.1 - 1.4e-11 43.8 6.2 1.9e-06 27.6 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX38515.1 - 5.9e-09 35.7 2.7 0.00019 21.6 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX38515.1 - 9.6e-08 31.5 0.5 0.00015 21.6 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX38515.1 - 1.2e-05 25.7 0.4 0.13 13.2 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX38515.1 - 3.4e-05 24.3 3.7 0.0041 17.6 0.8 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 EKX38515.1 - 0.00057 19.5 0.6 0.00084 18.9 0.6 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain TPR_16 PF13432.6 EKX38515.1 - 0.00092 19.8 1.3 0.0013 19.3 0.4 1.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX38515.1 - 0.0038 17.8 0.2 1.5 9.6 0.0 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat PPR PF01535.20 EKX38515.1 - 0.0049 17.0 0.1 0.63 10.4 0.0 2.4 2 0 0 2 2 2 1 PPR repeat DUF4041 PF13250.6 EKX38515.1 - 0.0062 16.4 0.0 1 9.3 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4041) TPR_9 PF13371.6 EKX38515.1 - 0.0062 16.7 0.1 0.0099 16.0 0.1 1.4 1 1 0 1 1 1 1 Tetratricopeptide repeat BTAD PF03704.17 EKX38515.1 - 0.069 13.6 0.4 0.12 12.8 0.4 1.4 1 1 0 1 1 1 0 Bacterial transcriptional activator domain MIT PF04212.18 EKX38515.1 - 2.3 8.3 6.5 1 9.5 0.2 2.3 2 1 1 3 3 2 0 MIT (microtubule interacting and transport) domain Glyco_trans_1_2 PF13524.6 EKX38516.1 - 0.065 13.6 0.1 0.16 12.4 0.1 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 Acyl-CoA_dh_N PF02771.16 EKX38516.1 - 1.3 9.7 3.2 0.64 10.7 0.6 1.8 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain EF-1_beta_acid PF10587.9 EKX38516.1 - 6.2 7.4 9.7 5.7 7.5 2.9 2.8 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region DUF3950 PF13132.6 EKX38518.1 - 0.088 12.6 0.7 0.16 11.7 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3950) Hydrolase_4 PF12146.8 EKX38519.1 - 3.3e-09 36.3 0.0 9e-09 34.9 0.0 1.6 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EKX38519.1 - 9.7e-06 25.4 0.1 1.6e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EKX38519.1 - 7.5e-05 23.4 0.1 0.00012 22.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF818 PF05677.12 EKX38519.1 - 0.0024 16.9 0.0 0.004 16.2 0.0 1.4 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Patatin PF01734.22 EKX38521.1 - 3.4e-11 43.7 0.0 8.8e-11 42.4 0.0 1.7 1 1 0 1 1 1 1 Patatin-like phospholipase Methyltransf_16 PF10294.9 EKX38522.1 - 2.7e-09 37.0 0.3 5.8e-09 35.9 0.0 1.6 2 0 0 2 2 2 1 Lysine methyltransferase MTS PF05175.14 EKX38522.1 - 0.00044 19.8 0.1 0.00062 19.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EKX38522.1 - 0.0051 17.5 0.2 0.0085 16.8 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EKX38522.1 - 0.012 15.0 0.1 0.016 14.6 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Chorion_1 PF01723.16 EKX38522.1 - 0.039 13.9 0.9 1.5 8.8 0.4 2.1 2 0 0 2 2 2 0 Chorion protein Methyltransf_12 PF08242.12 EKX38522.1 - 0.069 13.9 0.1 0.11 13.3 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 EKX38522.1 - 0.18 11.4 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 EKX38522.1 - 0.24 11.2 0.5 0.65 9.8 0.4 1.7 2 0 0 2 2 2 0 Methyltransferase domain PH PF00169.29 EKX38524.1 - 0.011 16.3 0.0 0.036 14.6 0.0 1.8 2 0 0 2 2 2 0 PH domain LRR_6 PF13516.6 EKX38525.1 - 1.9e-23 80.4 11.1 0.00054 19.8 0.1 6.3 6 0 0 6 6 6 6 Leucine Rich repeat LRR_4 PF12799.7 EKX38525.1 - 6e-09 36.0 6.6 0.44 11.0 0.0 4.6 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX38525.1 - 7.7e-07 28.8 12.3 0.17 11.7 0.9 5.6 3 3 0 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 EKX38525.1 - 6.8e-06 25.9 7.1 13 6.8 0.0 6.1 4 1 1 5 5 5 3 Leucine Rich Repeat DNA_pol_A_exo1 PF01612.20 EKX38530.1 - 1.8e-43 148.3 0.0 2e-43 148.2 0.0 1.0 1 0 0 1 1 1 1 3'-5' exonuclease Bromodomain PF00439.25 EKX38531.1 - 4.9e-25 87.4 0.3 5.5e-25 87.2 0.3 1.0 1 0 0 1 1 1 1 Bromodomain AAA_18 PF13238.6 EKX38532.1 - 9.9e-16 58.5 0.2 1.6e-15 57.8 0.2 1.3 1 0 0 1 1 1 1 AAA domain PIG-L PF02585.17 EKX38532.1 - 0.016 15.8 0.0 0.022 15.4 0.0 1.2 1 0 0 1 1 1 0 GlcNAc-PI de-N-acetylase dNK PF01712.19 EKX38532.1 - 0.021 14.7 0.2 0.024 14.5 0.2 1.1 1 0 0 1 1 1 0 Deoxynucleoside kinase DUF1106 PF06523.11 EKX38532.1 - 0.13 12.3 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1106) Pkinase PF00069.25 EKX38533.1 - 1.9e-62 211.1 0.0 2.1e-62 210.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX38533.1 - 1.4e-31 109.8 0.0 1.6e-31 109.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX38533.1 - 4.2e-05 23.0 0.0 5.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EKX38533.1 - 0.00023 20.6 0.2 0.00036 20.0 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX38533.1 - 0.001 19.1 0.3 0.0065 16.4 0.2 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX38533.1 - 0.0015 17.3 0.0 0.0024 16.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EKX38533.1 - 0.026 13.5 0.3 0.033 13.1 0.3 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 EKX38533.1 - 0.33 10.5 1.0 4.6 6.8 0.2 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase PF00069.25 EKX38534.1 - 2e-55 188.0 0.0 2.2e-55 187.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX38534.1 - 1.1e-33 116.6 0.0 1.3e-33 116.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX38534.1 - 0.00027 20.4 0.1 0.0011 18.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.9 EKX38534.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.3 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.14 EKX38534.1 - 0.098 12.0 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1874 PF08960.10 EKX38535.1 - 0.0028 17.8 0.0 0.005 16.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1874) CENP-B_dimeris PF09026.10 EKX38535.1 - 0.18 12.2 7.5 0.39 11.1 7.5 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Vasculin PF15337.6 EKX38535.1 - 0.19 12.6 4.3 2.4 9.0 0.1 2.3 2 0 0 2 2 2 0 Vascular protein family Vasculin-like 1 Cwf_Cwc_15 PF04889.12 EKX38535.1 - 0.28 10.9 5.2 0.076 12.7 2.0 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 EKX38535.1 - 1.4 6.9 5.1 2.4 6.2 5.1 1.3 1 0 0 1 1 1 0 DNA polymerase phi SBF PF01758.16 EKX38536.1 - 1.2e-19 70.7 12.4 1.2e-19 70.7 12.4 1.8 2 0 0 2 2 2 1 Sodium Bile acid symporter family Renin_r PF07850.14 EKX38536.1 - 0.52 10.9 3.7 18 6.0 1.6 3.0 2 1 0 2 2 2 0 Renin receptor-like protein DUF5518 PF17647.1 EKX38536.1 - 1.1 9.5 11.3 0.048 13.8 1.7 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5518) Epiglycanin_C PF14654.6 EKX38536.1 - 1.7 8.7 6.6 9.8 6.3 0.4 3.3 3 1 0 3 3 3 0 Mucin, catalytic, TM and cytoplasmic tail region EF-hand_6 PF13405.6 EKX38537.1 - 0.0041 16.9 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 EKX38537.1 - 0.23 11.1 0.9 0.49 10.1 0.1 2.0 2 0 0 2 2 2 0 EF hand DUF1388 PF07142.12 EKX38538.1 - 4.4e-07 29.7 39.6 0.017 15.1 4.5 5.1 1 1 3 5 5 5 5 Repeat of unknown function (DUF1388) DUF5561 PF17716.1 EKX38539.1 - 2.7e-36 125.2 0.2 4.1e-36 124.6 0.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5561) Mito_carr PF00153.27 EKX38540.1 - 1.6e-54 181.8 4.8 1.8e-22 79.1 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein ThrE_2 PF12821.7 EKX38540.1 - 0.035 14.2 1.5 0.035 14.2 1.5 2.1 2 0 0 2 2 2 0 Threonine/Serine exporter, ThrE GxDLY PF14607.6 EKX38540.1 - 0.11 12.3 0.1 8.9 6.1 0.0 2.6 3 0 0 3 3 3 0 N-terminus of Esterase_SGNH_hydro-type GBP PF02263.19 EKX38541.1 - 8.3e-54 182.6 0.0 9.7e-54 182.4 0.0 1.0 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Septin PF00735.18 EKX38541.1 - 0.0047 16.2 0.0 0.0079 15.5 0.0 1.3 1 0 0 1 1 1 1 Septin Dynamin_N PF00350.23 EKX38541.1 - 0.0068 16.5 0.2 0.72 9.9 0.1 2.3 1 1 1 2 2 2 2 Dynamin family RHD3 PF05879.12 EKX38541.1 - 0.033 12.4 0.2 0.097 10.8 0.1 1.7 2 0 0 2 2 2 0 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 EKX38541.1 - 0.087 12.9 0.1 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase ANAPC4_WD40 PF12894.7 EKX38542.1 - 3.1e-17 62.7 0.1 0.0064 16.8 0.0 5.7 5 2 1 6 6 4 4 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 EKX38542.1 - 3.2e-16 59.5 26.9 0.00047 20.1 0.2 11.1 6 3 5 11 11 11 4 Region in Clathrin and VPS WD40 PF00400.32 EKX38542.1 - 5e-14 52.5 2.3 0.014 16.2 0.0 6.5 7 0 0 7 7 6 3 WD domain, G-beta repeat TPR_19 PF14559.6 EKX38542.1 - 2.8e-06 27.8 28.0 0.22 12.0 0.1 9.6 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX38542.1 - 0.0011 19.5 34.8 10 7.3 0.2 14.7 15 3 2 17 17 15 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX38542.1 - 0.0012 19.0 18.8 2.4 8.5 0.0 9.9 8 3 3 11 11 10 1 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_WDAD PF04053.14 EKX38542.1 - 0.0019 17.4 6.4 0.15 11.1 1.5 4.8 3 1 2 5 5 5 1 Coatomer WD associated region Sec16_C PF12931.7 EKX38542.1 - 0.0042 16.8 11.9 0.81 9.3 0.3 4.8 4 1 1 5 5 5 2 Sec23-binding domain of Sec16 TPR_7 PF13176.6 EKX38542.1 - 0.0094 15.9 30.9 7.2 6.9 0.0 13.2 14 5 0 14 14 11 1 Tetratricopeptide repeat PPR PF01535.20 EKX38542.1 - 0.018 15.3 17.3 36 4.9 0.0 9.7 12 0 0 12 12 9 0 PPR repeat TPR_11 PF13414.6 EKX38542.1 - 0.036 13.8 13.9 7.1 6.4 0.1 8.3 9 1 0 9 9 9 0 TPR repeat TPR_2 PF07719.17 EKX38542.1 - 0.062 13.4 44.1 25 5.3 0.0 15.3 17 2 1 18 18 16 0 Tetratricopeptide repeat Leuk-A4-hydro_C PF09127.11 EKX38542.1 - 0.078 13.1 2.9 3.8 7.6 0.0 4.4 3 1 1 4 4 4 0 Leukotriene A4 hydrolase, C-terminal TPR_10 PF13374.6 EKX38542.1 - 0.89 9.5 17.9 39 4.3 0.0 9.2 10 0 0 10 10 9 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EKX38542.1 - 0.96 9.4 14.2 7.1 6.6 0.2 6.2 7 0 0 7 7 7 0 Mad3/BUB1 homology region 1 TPR_8 PF13181.6 EKX38542.1 - 1.8 9.0 32.0 47 4.6 0.0 12.4 11 3 4 15 15 15 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX38542.1 - 2.8 8.8 22.8 31 5.5 0.1 10.9 13 0 0 13 13 9 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX38542.1 - 4.6 7.6 33.1 14 6.0 0.2 12.0 14 3 3 17 17 15 0 Tetratricopeptide repeat TPR_1 PF00515.28 EKX38542.1 - 7.7 6.5 45.8 7 6.7 0.4 13.6 16 1 1 17 17 16 0 Tetratricopeptide repeat Bacteriocin_IIc PF10439.9 EKX38543.1 - 0.13 12.4 10.7 0.22 11.7 10.7 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_YMGG PF13441.6 EKX38543.1 - 0.54 10.0 17.7 0.95 9.3 17.7 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper LRR_8 PF13855.6 EKX38544.1 - 1.4e-39 133.6 27.9 9.1e-14 51.0 3.8 5.1 2 1 3 5 5 5 5 Leucine rich repeat LRR_5 PF13306.6 EKX38544.1 - 1.2e-19 70.5 0.0 2.1e-10 40.6 0.0 3.2 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 EKX38544.1 - 3.5e-17 62.2 22.8 0.00014 22.2 2.4 5.8 4 2 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX38544.1 - 0.0013 18.3 0.2 2.4 7.7 0.0 2.7 1 1 2 3 3 3 2 Leucine-rich repeat GIT_SHD PF08518.11 EKX38544.1 - 0.0024 17.5 0.2 12 5.6 0.0 5.3 6 0 0 6 6 6 1 Spa2 homology domain (SHD) of GIT GalKase_gal_bdg PF10509.9 EKX38544.1 - 0.023 14.3 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Galactokinase galactose-binding signature LRR_1 PF00560.33 EKX38544.1 - 7 7.6 24.2 33 5.6 0.0 7.8 8 1 0 8 8 8 0 Leucine Rich Repeat SET PF00856.28 EKX38545.1 - 1.1e-07 32.4 0.0 1.4e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 SET domain Pre-SET PF05033.16 EKX38545.1 - 0.00011 22.7 1.8 0.00015 22.4 1.3 1.4 2 0 0 2 2 2 1 Pre-SET motif DUF3458_C PF17432.2 EKX38546.1 - 5.3e-108 361.2 6.1 8.7e-108 360.5 6.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 EKX38546.1 - 1.2e-53 181.9 0.3 2.9e-53 180.7 0.2 1.6 2 0 0 2 2 2 1 Peptidase family M1 domain DUF3458 PF11940.8 EKX38546.1 - 4.2e-31 107.3 0.0 1e-30 106.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 EKX38546.1 - 1e-17 64.9 0.0 1.9e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 EKX38546.1 - 0.0086 16.5 0.0 0.06 13.7 0.0 2.5 2 0 0 2 2 2 1 M61 glycyl aminopeptidase DUF2268 PF10026.9 EKX38546.1 - 0.023 14.3 0.0 0.083 12.5 0.0 1.9 2 0 0 2 2 2 0 Predicted Zn-dependent protease (DUF2268) HECT PF00632.25 EKX38551.1 - 8.5e-24 84.6 0.0 6.1e-19 68.6 0.0 2.3 2 0 0 2 2 2 2 HECT-domain (ubiquitin-transferase) Pox_A3L PF05288.11 EKX38552.1 - 0.13 12.3 3.5 1.4 9.0 0.3 3.4 2 1 0 2 2 2 0 Poxvirus A3L Protein LPP PF04728.13 EKX38552.1 - 4.1 7.9 19.4 1.2 9.6 0.8 5.5 6 0 0 6 6 6 0 Lipoprotein leucine-zipper NAD_Gly3P_dh_N PF01210.23 EKX38553.1 - 1.5e-48 164.7 0.2 2.3e-48 164.1 0.2 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EKX38553.1 - 3.6e-47 160.2 0.1 7.2e-47 159.2 0.1 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Pan3_PK PF18101.1 EKX38553.1 - 0.068 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Pan3 Pseudokinase domain REGB_T4 PF10715.9 EKX38554.1 - 0.1 12.8 0.1 0.18 12.0 0.1 1.3 1 1 0 1 1 1 0 T4-page Endoribonuclease RegB CobN-Mg_chel PF02514.16 EKX38555.1 - 2e-291 969.6 0.0 1.2e-145 486.9 0.0 2.0 1 1 1 2 2 2 2 CobN/Magnesium Chelatase DUF3479 PF11965.8 EKX38555.1 - 3.6e-48 163.7 0.0 1.4e-47 161.9 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3479) UPF0180 PF03698.13 EKX38555.1 - 0.054 13.7 0.1 2.4 8.4 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) MutS_V PF00488.21 EKX38556.1 - 3.1e-38 131.7 0.4 4.9e-38 131.0 0.4 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EKX38556.1 - 2.4e-25 89.9 1.2 5.5e-25 88.7 0.6 1.8 2 0 0 2 2 2 1 MutS domain III SNCAIP_SNCA_bd PF16700.5 EKX38557.1 - 0.91 9.3 5.9 1.7 8.5 4.5 2.2 2 0 0 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain DUF4407 PF14362.6 EKX38557.1 - 1.1 8.6 12.0 0.098 12.0 5.8 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) LMBR1 PF04791.16 EKX38557.1 - 1.6 7.5 6.4 3.1 6.6 6.4 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DLP_helical PF18709.1 EKX38557.1 - 4.9 6.3 16.2 8.1 5.5 4.1 3.4 1 1 2 3 3 3 0 Dynamin-like helical domain UPF0242 PF06785.11 EKX38557.1 - 5.7 7.0 25.5 0.044 13.9 13.1 2.9 2 2 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 EKX38557.1 - 6.7 6.2 14.4 4.7 6.7 11.9 1.9 1 1 1 2 2 2 0 Exonuclease VII, large subunit Senescence PF06911.12 EKX38559.1 - 4.4e-20 72.8 1.3 8e-20 71.9 1.3 1.4 1 0 0 1 1 1 1 Senescence-associated protein PDZ_6 PF17820.1 EKX38559.1 - 7.9e-10 38.4 1.6 1.2e-09 37.8 0.7 1.9 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX38559.1 - 4.2e-07 30.2 0.6 1.3e-06 28.6 0.6 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX38559.1 - 0.00012 22.3 0.1 0.00038 20.7 0.1 1.9 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX38559.1 - 0.0005 20.0 1.7 0.0014 18.6 0.2 2.5 3 0 0 3 3 3 1 Tricorn protease PDZ domain PH PF00169.29 EKX38559.1 - 0.00055 20.4 0.0 0.0024 18.3 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 EKX38559.1 - 0.0062 16.4 0.1 0.011 15.5 0.1 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 EKX38559.1 - 0.016 15.6 0.0 0.035 14.5 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Glyco_trans_1_2 PF13524.6 EKX38561.1 - 1.6e-13 50.9 0.1 3.1e-13 49.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF563 PF04577.14 EKX38561.1 - 2.3e-08 34.4 0.1 2.8e-07 30.9 0.1 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Glycos_transf_1 PF00534.20 EKX38561.1 - 0.019 14.5 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 Spermine_synth PF01564.17 EKX38562.1 - 4.2e-63 212.2 0.0 5.6e-63 211.8 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EKX38562.1 - 6.3e-21 74.0 0.2 1.1e-20 73.3 0.2 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 EKX38562.1 - 0.0013 19.4 0.1 0.0035 18.0 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EKX38562.1 - 0.0057 16.6 0.0 0.0087 16.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX38562.1 - 0.023 15.4 0.1 1.1 10.0 0.0 2.8 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_2 PF00891.18 EKX38562.1 - 0.08 12.2 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Zn_clus PF00172.18 EKX38563.1 - 9.4e-11 41.7 27.7 6e-06 26.3 10.4 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain RolB_RolC PF02027.17 EKX38563.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 RolB/RolC glucosidase family TPR_17 PF13431.6 EKX38564.1 - 6.5e-28 95.1 6.5 0.0063 16.8 0.0 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.6 EKX38564.1 - 2.8e-19 68.2 0.3 0.0043 17.7 0.0 8.1 4 3 4 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 EKX38564.1 - 7.4e-19 66.7 11.2 0.033 14.0 0.0 9.1 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 EKX38564.1 - 2.1e-17 61.8 12.2 0.0038 17.2 0.0 9.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX38564.1 - 1.5e-16 59.2 3.3 0.0058 16.8 0.1 8.9 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX38564.1 - 1.1e-15 57.0 5.6 0.0031 17.2 0.0 7.7 8 1 1 9 9 9 4 TPR repeat TPR_12 PF13424.6 EKX38564.1 - 1.4e-14 54.1 8.9 0.0068 16.7 0.2 6.5 5 3 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 EKX38564.1 - 2e-11 44.2 6.4 0.012 16.2 0.0 5.8 4 3 2 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX38564.1 - 6.5e-08 32.2 7.0 0.19 11.6 0.0 7.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX38564.1 - 3e-07 30.0 4.8 4.3 7.6 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX38564.1 - 2.3e-05 25.0 0.8 3.8 8.2 0.0 5.6 7 1 0 7 7 5 1 Tetratricopeptide repeat Coatomer_E PF04733.14 EKX38564.1 - 0.0058 16.1 0.8 7 6.0 0.0 3.5 3 1 1 4 4 4 2 Coatomer epsilon subunit ANAPC3 PF12895.7 EKX38564.1 - 0.029 14.6 1.5 11 6.3 0.0 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EKX38564.1 - 0.044 13.9 0.1 7.5 6.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 EKX38564.1 - 0.11 12.8 1.1 0.72 10.2 0.0 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat ComR_TPR PF18710.1 EKX38564.1 - 0.13 11.8 1.8 23 4.4 0.1 3.4 3 1 1 4 4 4 0 ComR tetratricopeptide TPR_6 PF13174.6 EKX38564.1 - 0.92 10.3 5.1 41 5.1 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat RR_TM4-6 PF06459.12 EKX38566.1 - 0.0021 17.9 23.6 0.0024 17.8 23.6 1.1 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 CDC27 PF09507.10 EKX38566.1 - 0.0022 17.5 24.8 0.0022 17.5 24.8 1.3 2 0 0 2 2 2 1 DNA polymerase subunit Cdc27 Spore_coat_CotO PF14153.6 EKX38566.1 - 0.25 11.2 28.9 0.4 10.6 28.9 1.4 1 0 0 1 1 1 0 Spore coat protein CotO PPP4R2 PF09184.11 EKX38566.1 - 0.61 9.6 25.9 0.77 9.3 25.9 1.1 1 0 0 1 1 1 0 PPP4R2 DUF4045 PF13254.6 EKX38566.1 - 1.3 8.5 25.3 1.6 8.3 25.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) GAGA_bind PF06217.12 EKX38566.1 - 7.6 6.7 12.2 8.7 6.5 12.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family FAM60A PF15396.6 EKX38566.1 - 8.9 6.2 12.8 14 5.6 12.8 1.3 1 0 0 1 1 1 0 Protein Family FAM60A CDC45 PF02724.14 EKX38568.1 - 0.092 11.0 12.2 0.12 10.6 12.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 EKX38568.1 - 0.094 10.8 11.2 0.13 10.4 11.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 EKX38568.1 - 0.14 10.3 14.1 0.2 9.8 14.1 1.1 1 0 0 1 1 1 0 Nop14-like family SAB PF04382.13 EKX38568.1 - 0.21 11.7 1.9 0.49 10.5 1.9 1.6 1 0 0 1 1 1 0 SAB domain TFIIF_alpha PF05793.12 EKX38568.1 - 0.34 9.4 14.1 0.46 9.0 14.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FAM76 PF16046.5 EKX38568.1 - 0.61 9.4 7.4 0.88 8.9 7.4 1.1 1 0 0 1 1 1 0 FAM76 protein Apt1 PF10351.9 EKX38568.1 - 0.76 8.6 6.7 1.1 8.0 6.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain eIF-3c_N PF05470.12 EKX38568.1 - 1.9 6.7 9.7 2.8 6.2 9.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Pox_Ag35 PF03286.14 EKX38568.1 - 2.4 7.9 17.4 10 5.9 15.9 2.2 2 1 0 2 2 2 0 Pox virus Ag35 surface protein Nop53 PF07767.11 EKX38568.1 - 2.6 7.3 14.4 3.6 6.9 14.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PDZ_6 PF17820.1 EKX38569.1 - 1.1e-12 47.6 0.6 1.6e-05 24.6 0.2 2.7 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 EKX38569.1 - 2.4e-11 43.8 2.3 0.00012 22.3 0.0 2.9 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 EKX38569.1 - 9.6e-10 38.7 0.1 0.0023 18.2 0.1 2.6 2 0 0 2 2 2 2 PDZ domain GRASP55_65 PF04495.14 EKX38569.1 - 3.5e-06 27.4 0.0 0.0008 19.7 0.1 2.4 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain Tricorn_PDZ PF14685.6 EKX38569.1 - 0.00012 22.0 0.0 0.062 13.3 0.0 2.5 2 0 0 2 2 2 2 Tricorn protease PDZ domain IQ PF00612.27 EKX38569.1 - 0.03 14.1 4.7 0.82 9.6 0.2 2.8 2 0 0 2 2 2 0 IQ calmodulin-binding motif EF-hand_7 PF13499.6 EKX38569.1 - 0.057 13.9 0.1 0.23 11.9 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 EKX38569.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 EKX38569.1 - 0.14 12.1 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain Prominin PF05478.11 EKX38571.1 - 0.008 14.2 0.6 0.011 13.7 0.6 1.1 1 0 0 1 1 1 1 Prominin PilJ PF13675.6 EKX38571.1 - 0.0097 15.9 0.8 0.26 11.3 0.2 2.8 1 1 1 2 2 2 1 Type IV pili methyl-accepting chemotaxis transducer N-term Baculo_PEP_C PF04513.12 EKX38571.1 - 0.054 13.5 0.1 0.086 12.9 0.1 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Kinesin PF00225.23 EKX38573.1 - 1.3e-70 238.0 2.6 1.4e-70 237.9 2.6 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX38573.1 - 3.2e-23 82.3 0.1 4.7e-23 81.8 0.1 1.3 1 0 0 1 1 1 1 Microtubule binding 5-nucleotidase PF06189.12 EKX38573.1 - 0.065 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 5'-nucleotidase Vps26 PF03643.15 EKX38574.1 - 1.4e-60 204.6 0.0 1.7e-60 204.4 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EKX38574.1 - 0.00013 22.1 0.0 0.00037 20.6 0.0 1.8 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain COG7 PF10191.9 EKX38575.1 - 2.3e-92 310.6 19.3 6.6e-92 309.1 19.3 1.7 1 1 0 1 1 1 1 Golgi complex component 7 (COG7) DDE_Tnp_ISL3 PF01610.17 EKX38575.1 - 0.00058 19.6 0.2 0.012 15.4 0.0 2.6 2 0 0 2 2 2 1 Transposase PI3K_P85_iSH2 PF16454.5 EKX38575.1 - 0.031 13.9 0.2 0.031 13.9 0.2 2.9 2 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4164 PF13747.6 EKX38575.1 - 4.1 7.8 9.6 9.2 6.6 0.7 4.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4164) Ephrin_rec_like PF07699.13 EKX38576.1 - 2.7e-38 129.5 94.7 3.6e-09 36.2 8.6 10.4 5 5 5 10 10 10 9 Putative ephrin-receptor like NCD3G PF07562.14 EKX38576.1 - 7.5e-08 32.2 70.1 0.00088 19.2 3.1 9.1 3 3 6 10 10 10 9 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX38576.1 - 0.0034 17.7 73.9 0.51 10.8 0.4 12.6 3 3 10 13 13 13 8 TNFR/NGFR cysteine-rich region VSP PF03302.13 EKX38576.1 - 0.065 12.1 83.7 0.2 10.5 15.5 5.0 1 1 4 5 5 5 0 Giardia variant-specific surface protein Lipase_3 PF01764.25 EKX38577.1 - 3.5e-07 30.2 0.0 1.2e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 Lipase (class 3) Snapin_Pallidin PF14712.6 EKX38577.1 - 0.0033 17.8 2.3 0.14 12.6 0.4 2.7 2 0 0 2 2 2 1 Snapin/Pallidin DivIC PF04977.15 EKX38577.1 - 0.006 16.3 1.3 0.8 9.5 0.1 2.6 2 0 0 2 2 2 2 Septum formation initiator TssO PF17561.2 EKX38577.1 - 0.04 14.0 5.6 0.046 13.8 0.7 2.7 2 0 0 2 2 2 0 Type VI secretion system, TssO GlutR_dimer PF00745.20 EKX38577.1 - 0.088 13.3 0.4 0.58 10.6 0.0 2.5 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Vps51 PF08700.11 EKX38577.1 - 0.11 12.5 0.7 13 5.9 0.0 3.3 3 0 0 3 3 3 0 Vps51/Vps67 PI3K_P85_iSH2 PF16454.5 EKX38577.1 - 0.62 9.6 4.1 4.3 6.9 0.1 2.8 3 0 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain EF-hand_6 PF13405.6 EKX38578.1 - 0.0045 16.8 0.2 0.022 14.7 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 EKX38578.1 - 0.0065 15.9 1.5 0.047 13.2 0.5 2.8 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 EKX38578.1 - 0.051 13.1 0.2 0.2 11.3 0.2 2.1 1 0 0 1 1 1 0 EF hand zf-C2H2 PF00096.26 EKX38579.1 - 0.00025 21.3 0.4 0.00095 19.5 0.4 2.1 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 EKX38579.1 - 0.0021 17.9 2.7 0.006 16.4 2.7 1.9 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 EKX38579.1 - 0.0029 17.3 0.1 0.0076 16.0 0.1 1.8 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 EKX38579.1 - 0.019 15.8 1.8 0.13 13.1 1.8 2.6 1 0 0 1 1 1 0 C2H2-type zinc finger SOG2 PF10428.9 EKX38579.1 - 1.9 7.6 5.2 2.4 7.3 5.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Med7 PF05983.11 EKX38581.1 - 3.5e-11 43.5 8.9 3.5e-11 43.5 8.9 3.2 3 1 0 3 3 3 1 MED7 protein V-SNARE PF05008.15 EKX38581.1 - 0.17 12.3 0.3 0.17 12.3 0.3 2.3 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus TEBP_beta PF07404.11 EKX38581.1 - 3.2 7.0 10.4 4.2 6.6 10.4 1.1 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) PRP21_like_P PF12230.8 EKX38582.1 - 1.1e-43 149.6 5.4 1.1e-43 149.6 5.4 1.9 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 EKX38582.1 - 3.5e-39 132.6 1.3 3.3e-19 68.6 0.2 2.3 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.23 EKX38583.1 - 0.00031 20.4 0.0 0.00059 19.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 EKX38583.1 - 0.018 15.5 0.1 0.037 14.5 0.1 1.5 1 1 0 1 1 1 0 Ubiquitin-like domain Metallophos PF00149.28 EKX38584.1 - 2.8e-23 83.5 0.0 3.9e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase VirB3 PF05101.13 EKX38585.1 - 0.0027 17.9 1.3 0.0037 17.5 1.3 1.2 1 0 0 1 1 1 1 Type IV secretory pathway, VirB3-like protein Glyco_trans_4_5 PF16994.5 EKX38585.1 - 0.019 14.6 0.2 0.019 14.6 0.2 1.1 1 0 0 1 1 1 0 Glycosyl-transferase family 4 Herpes_US12 PF05363.12 EKX38585.1 - 0.14 12.9 0.3 0.19 12.5 0.3 1.2 1 0 0 1 1 1 0 Herpesvirus US12 family PhoR PF11808.8 EKX38585.1 - 0.71 10.3 3.2 0.95 9.9 3.2 1.2 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR Laminin_G_3 PF13385.6 EKX38586.1 - 3e-11 43.7 0.8 0.00027 21.1 0.3 2.3 1 1 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily HTH_Tnp_Tc5 PF03221.16 EKX38587.1 - 3.1e-07 30.3 0.0 8.2e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 Tc5 transposase DNA-binding domain PDZ_2 PF13180.6 EKX38587.1 - 5.9e-06 26.5 1.0 1.3e-05 25.4 1.0 1.6 1 1 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX38587.1 - 2.4e-05 24.1 0.2 3.7e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX38587.1 - 3.2e-05 24.2 0.1 6.3e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 PDZ domain HTH_17 PF12728.7 EKX38587.1 - 0.093 12.9 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain NPA PF16469.5 EKX38587.1 - 0.21 12.1 1.9 0.28 11.7 0.9 1.8 2 0 0 2 2 2 0 Nematode polyprotein allergen ABA-1 DSPn PF14671.6 EKX38588.1 - 3.2e-37 128.1 0.2 9.5e-37 126.6 0.0 1.8 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EKX38588.1 - 3.3e-14 52.8 0.0 7.6e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX38588.1 - 5.1e-06 26.2 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX38588.1 - 1.4e-05 25.2 0.0 3.2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EKX38588.1 - 0.03 14.3 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family EIIA-man PF03610.16 EKX38589.1 - 0.0026 18.0 0.4 0.024 14.8 0.0 2.3 2 0 0 2 2 2 1 PTS system fructose IIA component NAD_binding_9 PF13454.6 EKX38589.1 - 0.053 13.5 0.2 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding AAA_23 PF13476.6 EKX38589.1 - 0.34 11.4 10.5 0.067 13.7 6.7 1.7 1 1 1 2 2 2 0 AAA domain Prominin PF05478.11 EKX38589.1 - 2.2 6.2 4.1 3.5 5.5 4.1 1.2 1 0 0 1 1 1 0 Prominin ALG11_N PF15924.5 EKX38590.1 - 4.6e-87 291.4 0.0 6.4e-87 291.0 0.0 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EKX38590.1 - 2.1e-25 89.2 0.0 3.1e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EKX38590.1 - 5.1e-14 52.8 0.0 1.8e-13 51.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 QH-AmDH_gamma PF08992.11 EKX38590.1 - 0.032 14.2 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, gamma subunit Stevor PF17410.2 EKX38590.1 - 0.82 9.2 4.4 1.3 8.6 4.4 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Glyco_hydro_20 PF00728.22 EKX38591.1 - 7.3e-77 259.1 0.0 8.2e-77 259.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Nramp PF01566.18 EKX38592.1 - 1.6e-115 385.9 24.1 2.1e-115 385.6 24.1 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein LptF_LptG PF03739.14 EKX38592.1 - 0.4 9.5 12.1 1.2 7.9 12.1 1.8 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF4337 PF14235.6 EKX38593.1 - 0.0048 17.0 0.1 0.0089 16.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4337) DUF2207 PF09972.9 EKX38593.1 - 0.0057 15.5 0.0 0.0066 15.3 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) ATG22 PF11700.8 EKX38593.1 - 0.01 14.5 0.0 0.013 14.2 0.0 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like DUF4181 PF13789.6 EKX38593.1 - 0.033 14.4 1.6 0.075 13.3 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) FYVE_2 PF02318.16 EKX38593.1 - 0.11 12.7 0.7 0.23 11.7 0.7 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Halogen_Hydrol PF10112.9 EKX38593.1 - 0.28 11.2 4.1 0.95 9.5 0.1 2.3 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein LPP PF04728.13 EKX38594.1 - 0.018 15.4 0.8 0.036 14.4 0.8 1.5 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Thioredoxin_6 PF13848.6 EKX38594.1 - 0.067 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain DUF3138 PF11336.8 EKX38594.1 - 0.33 9.5 0.8 4.5 5.8 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) PCNA_N PF00705.18 EKX38596.1 - 1.5e-56 189.5 1.7 2.7e-56 188.7 1.7 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 EKX38596.1 - 1.1e-54 184.0 0.1 2.9e-54 182.6 0.1 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 EKX38596.1 - 6.2e-09 35.3 2.1 3.3e-08 32.9 2.1 1.8 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 EKX38596.1 - 1.1e-06 28.3 0.1 1.3e-06 28.1 0.1 1.0 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 EKX38596.1 - 0.0056 15.8 0.2 0.55 9.3 0.1 2.1 2 0 0 2 2 2 2 Hus1-like protein Porin_OmpL1 PF11389.8 EKX38596.1 - 0.026 13.8 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 Leptospira porin protein OmpL1 RNase_P_pop3 PF08228.11 EKX38596.1 - 0.13 12.3 0.2 1.1 9.3 0.0 2.3 1 1 0 3 3 3 0 RNase P subunit Pop3 TFIIF_alpha PF05793.12 EKX38597.1 - 0.76 8.3 39.9 0.93 8.0 39.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Macoilin PF09726.9 EKX38597.1 - 1.9 7.0 19.6 2.3 6.7 19.6 1.1 1 0 0 1 1 1 0 Macoilin family SID-1_RNA_chan PF13965.6 EKX38597.1 - 2.2 6.6 3.0 3 6.1 3.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PA26 PF04636.13 EKX38597.1 - 9.9 5.0 10.3 14 4.5 10.3 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) TIG PF01833.24 EKX38598.1 - 6.5e-13 48.6 0.1 1.1e-07 31.8 0.0 3.4 3 0 0 3 3 3 2 IPT/TIG domain Ist1 PF03398.14 EKX38599.1 - 9.7e-15 54.9 0.1 1.2e-14 54.5 0.1 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Sec2p PF06428.11 EKX38600.1 - 0.043 13.8 7.3 0.068 13.1 0.3 3.0 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p DUF3151 PF11349.8 EKX38600.1 - 0.063 13.4 0.3 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3151) DUF4317 PF14199.6 EKX38600.1 - 0.092 11.9 0.3 0.13 11.4 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4317) Spc7 PF08317.11 EKX38600.1 - 0.15 10.9 7.8 0.22 10.4 7.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Tup_N PF08581.10 EKX38600.1 - 0.29 11.4 5.8 7.1 7.0 0.1 2.9 1 1 2 3 3 3 0 Tup N-terminal Golgin_A5 PF09787.9 EKX38600.1 - 0.38 10.2 11.4 2 7.8 11.4 1.9 1 1 0 1 1 1 0 Golgin subfamily A member 5 AAA_11 PF13086.6 EKX38600.1 - 0.57 9.9 4.5 0.78 9.5 4.5 1.1 1 0 0 1 1 1 0 AAA domain Troponin PF00992.20 EKX38600.1 - 1.1 9.6 10.5 1.4 9.2 8.4 1.9 1 1 1 2 2 2 0 Troponin TPR_MLP1_2 PF07926.12 EKX38600.1 - 2.7 8.0 15.8 1.4 9.0 11.8 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 EKX38600.1 - 3.8 6.8 9.2 5.4 6.3 7.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ADIP PF11559.8 EKX38600.1 - 3.9 7.5 12.1 8.9 6.4 1.0 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding PDZ_6 PF17820.1 EKX38601.1 - 4e-27 93.8 10.8 1.2e-05 25.1 0.2 5.1 5 0 0 5 5 5 4 PDZ domain Pkinase PF00069.25 EKX38601.1 - 1.3e-26 93.5 0.0 7.4e-26 91.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain PDZ PF00595.24 EKX38601.1 - 2.4e-26 91.9 8.0 1.9e-08 34.5 0.1 5.0 4 1 0 4 4 4 4 PDZ domain PDZ_2 PF13180.6 EKX38601.1 - 9.9e-23 80.3 2.6 4.2e-05 23.8 0.0 4.6 4 0 0 4 4 4 4 PDZ domain Pkinase_Tyr PF07714.17 EKX38601.1 - 1e-17 64.3 0.0 1.7e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Tricorn_PDZ PF14685.6 EKX38601.1 - 9.1e-11 41.6 0.3 0.17 11.9 0.0 4.9 4 0 0 4 4 4 4 Tricorn protease PDZ domain KHA PF11834.8 EKX38601.1 - 0.0024 17.9 0.0 0.0066 16.5 0.0 1.8 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel CHB_HEX_C_1 PF13290.6 EKX38602.1 - 2.2e-06 27.6 0.0 0.0089 16.0 0.0 3.2 3 1 0 3 3 3 2 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 EKX38602.1 - 0.00039 20.5 0.0 0.084 13.0 0.0 2.8 2 0 0 2 2 2 2 Fn3 associated Methyltransf_25 PF13649.6 EKX38603.1 - 7.5e-11 42.6 0.0 1.5e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EKX38603.1 - 2e-09 37.3 0.0 2.8e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EKX38603.1 - 2e-08 34.8 0.0 4.4e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX38603.1 - 6.1e-08 32.6 0.0 1.1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX38603.1 - 1.4e-06 28.3 0.0 7.6e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 EKX38603.1 - 3e-05 23.5 0.0 4.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EKX38603.1 - 0.00013 21.6 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 EKX38603.1 - 0.00014 20.9 0.1 0.00023 20.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 EKX38603.1 - 0.00058 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX38603.1 - 0.0016 19.1 0.0 0.0041 17.8 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EKX38603.1 - 0.032 14.2 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EKX38603.1 - 0.05 13.3 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 EKX38603.1 - 0.096 12.3 0.0 0.26 10.9 0.0 1.7 1 1 0 1 1 1 0 Conserved hypothetical protein 95 PRMT5 PF05185.16 EKX38603.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_24 PF13578.6 EKX38603.1 - 0.14 13.2 0.0 0.56 11.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Exostosin PF03016.15 EKX38604.1 - 4.9e-08 32.5 0.2 2.8e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 Exostosin family NHL PF01436.21 EKX38605.1 - 3.4e-06 26.8 0.0 1 9.6 0.0 4.2 4 0 0 4 4 4 2 NHL repeat Lactonase PF10282.9 EKX38605.1 - 0.0022 17.3 0.0 0.35 10.1 0.0 2.1 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller Arylesterase PF01731.20 EKX38605.1 - 0.039 14.2 0.0 0.21 11.8 0.0 2.1 3 0 0 3 3 3 0 Arylesterase LRR_8 PF13855.6 EKX38605.1 - 0.06 13.1 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 Leucine rich repeat Str_synth PF03088.16 EKX38605.1 - 0.067 13.3 0.0 5.8 7.1 0.0 2.6 3 0 0 3 3 3 0 Strictosidine synthase Ephrin_rec_like PF07699.13 EKX38606.1 - 1.1e-39 134.0 57.9 7.2e-08 32.1 2.7 7.5 2 2 5 7 7 7 7 Putative ephrin-receptor like NCD3G PF07562.14 EKX38606.1 - 4.7e-14 52.1 50.5 9.6e-05 22.3 8.3 6.9 2 2 2 6 6 6 6 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX38606.1 - 6.1e-07 29.7 44.7 0.07 13.5 0.1 8.5 3 2 7 10 10 10 8 TNFR/NGFR cysteine-rich region DUF2318 PF10080.9 EKX38606.1 - 0.043 13.9 1.4 0.043 13.9 1.4 6.5 2 2 5 7 7 7 0 Predicted membrane protein (DUF2318) VSP PF03302.13 EKX38606.1 - 0.56 9.0 51.4 0.72 8.6 24.2 3.5 1 1 3 4 4 4 0 Giardia variant-specific surface protein Spore_coat_CotO PF14153.6 EKX38607.1 - 0.0081 16.1 6.4 0.0097 15.9 6.4 1.2 1 0 0 1 1 1 1 Spore coat protein CotO Presenilin PF01080.17 EKX38607.1 - 0.03 13.1 0.7 0.034 12.9 0.7 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 EKX38607.1 - 0.52 9.0 3.9 0.54 8.9 3.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MAJIN PF15077.6 EKX38607.1 - 1.2 8.9 5.9 1.7 8.4 5.9 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein CENP-U PF13097.6 EKX38607.1 - 2.3 8.1 12.5 3.3 7.6 12.5 1.1 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit DDE_Tnp_1_7 PF13843.6 EKX38610.1 - 2.9e-14 53.1 0.0 3.3e-14 53.0 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 EF_assoc_2 PF08356.12 EKX38612.1 - 5.1e-21 74.5 0.1 2.6e-20 72.2 0.0 2.3 2 1 0 2 2 2 1 EF hand associated Ras PF00071.22 EKX38612.1 - 6.3e-19 68.2 0.0 5.8e-18 65.0 0.0 2.0 2 0 0 2 2 2 1 Ras family EF_assoc_1 PF08355.12 EKX38612.1 - 2e-11 43.3 0.0 4.2e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 EF hand associated Roc PF08477.13 EKX38612.1 - 1.4e-10 41.4 0.0 4.1e-10 39.9 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase EF-hand_6 PF13405.6 EKX38612.1 - 3.9e-08 32.6 1.4 0.00035 20.3 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EKX38612.1 - 6.5e-06 26.5 0.1 0.017 15.5 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX38612.1 - 1.3e-05 24.3 3.1 0.0064 16.0 0.1 2.9 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 EKX38612.1 - 2.4e-05 23.6 1.2 0.0047 16.4 0.1 2.6 2 0 0 2 2 2 2 EF hand GTP_EFTU PF00009.27 EKX38612.1 - 0.00042 19.9 0.0 0.0021 17.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EKX38612.1 - 0.0013 18.6 0.0 0.25 11.2 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase SPARC_Ca_bdg PF10591.9 EKX38612.1 - 0.0033 17.7 0.0 3.2 8.1 0.0 3.0 2 1 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 EKX38612.1 - 0.01 15.6 0.5 1.5 8.7 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_10 PF14788.6 EKX38612.1 - 0.055 13.3 0.4 2.8 7.9 0.0 2.4 2 0 0 2 2 2 0 EF hand MMR_HSR1 PF01926.23 EKX38612.1 - 0.096 12.8 0.0 0.22 11.6 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF3029 PF11230.8 EKX38612.1 - 0.16 10.3 0.0 0.22 9.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3029) tRNA-synt_1 PF00133.22 EKX38613.1 - 8.4e-35 120.1 0.5 1.3e-12 46.8 0.2 4.5 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EKX38613.1 - 9.1e-19 67.5 0.3 2e-10 40.0 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EKX38613.1 - 1.3e-15 57.7 0.0 4.9e-15 55.8 0.0 2.0 1 1 1 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EKX38613.1 - 8.2e-08 31.9 0.1 2.1e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1 PF00133.22 EKX38614.1 - 6.9e-40 136.9 0.1 7.3e-17 60.8 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EKX38614.1 - 1.4e-18 66.9 0.3 1.8e-10 40.1 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EKX38614.1 - 1.4e-15 57.6 0.0 4.2e-15 56.0 0.0 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EKX38614.1 - 9.8e-08 31.7 0.1 1.9e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Ank_2 PF12796.7 EKX38615.1 - 5.9e-24 84.5 2.0 7.7e-11 42.4 0.2 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX38615.1 - 1.9e-18 66.6 7.7 3.2e-07 30.8 0.2 4.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX38615.1 - 2.1e-18 66.1 3.7 0.00023 21.4 0.0 5.2 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX38615.1 - 6.7e-18 62.9 2.8 0.00062 20.0 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 EKX38615.1 - 7.9e-17 60.9 5.2 0.0018 18.7 0.0 4.7 3 1 1 4 4 4 4 Ankyrin repeat VWA_3_C PF18571.1 EKX38615.1 - 0.13 12.2 2.1 3.1 7.7 0.1 3.5 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain Acetyltransf_1 PF00583.25 EKX38616.1 - 1.5e-11 44.5 0.0 2.5e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family WW PF00397.26 EKX38616.1 - 1.3e-08 34.8 2.2 1.3e-08 34.8 2.2 1.7 2 0 0 2 2 2 1 WW domain FR47 PF08445.10 EKX38616.1 - 1.6e-08 34.4 0.0 2.8e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EKX38616.1 - 2.3e-08 34.0 0.0 4.5e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EKX38616.1 - 6.8e-07 29.6 0.0 1.3e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_hyd_101C PF17451.2 EKX38616.1 - 0.0056 17.0 0.1 0.011 16.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase 101 beta sandwich domain Acetyltransf_4 PF13420.7 EKX38616.1 - 0.059 13.5 0.0 0.098 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RWP-RK PF02042.15 EKX38617.1 - 8.1e-13 48.1 0.4 2.2e-12 46.8 0.0 1.8 2 0 0 2 2 2 1 RWP-RK domain HTH_28 PF13518.6 EKX38617.1 - 0.13 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain RWP-RK PF02042.15 EKX38618.1 - 1.3e-12 47.5 0.0 2.1e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_28 PF13518.6 EKX38618.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF761 PF05553.11 EKX38618.1 - 0.21 11.1 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Cotton fibre expressed protein RWP-RK PF02042.15 EKX38620.1 - 1.8e-14 53.4 0.1 3.1e-14 52.7 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain Ank_2 PF12796.7 EKX38621.1 - 8.5e-14 51.9 0.0 2.4e-09 37.7 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX38621.1 - 3e-10 39.4 0.6 0.99 10.2 0.1 5.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EKX38621.1 - 4.4e-10 39.9 0.0 0.00036 21.0 0.0 4.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX38621.1 - 4.6e-09 36.4 0.0 0.043 14.1 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX38621.1 - 0.00022 21.5 0.0 0.79 10.3 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ion_trans PF00520.31 EKX38621.1 - 0.73 9.0 30.1 3.3 6.9 28.0 2.4 1 1 1 2 2 2 0 Ion transport protein PPR_2 PF13041.6 EKX38623.1 - 1.5e-15 57.1 0.0 1.6e-07 31.4 0.0 3.6 3 0 0 3 3 3 3 PPR repeat family PPR_3 PF13812.6 EKX38623.1 - 8e-11 41.9 0.0 8.6e-05 22.5 0.0 3.2 2 1 1 3 3 3 3 Pentatricopeptide repeat domain PPR PF01535.20 EKX38623.1 - 7.2e-08 32.2 4.0 0.038 14.2 0.0 5.0 5 0 0 5 5 5 2 PPR repeat PPR_long PF17177.4 EKX38623.1 - 1.4e-06 27.8 1.5 0.046 13.1 0.2 2.7 1 1 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EKX38623.1 - 0.0019 17.9 0.1 0.23 11.2 0.0 3.2 3 0 0 3 3 3 1 PPR repeat Y2_Tnp PF04986.13 EKX38623.1 - 0.033 14.3 0.7 0.061 13.4 0.7 1.6 1 1 0 1 1 1 0 Putative transposase Phage_integr_3 PF16795.5 EKX38623.1 - 0.04 13.8 0.1 0.077 12.9 0.1 1.4 1 0 0 1 1 1 0 Archaeal phage integrase Melibiase PF02065.18 EKX38624.1 - 0.062 12.2 0.0 0.073 12.0 0.0 1.1 1 0 0 1 1 1 0 Melibiase DSPc PF00782.20 EKX38626.1 - 1.2e-24 86.6 0.0 1.3e-24 86.5 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX38626.1 - 0.0013 18.3 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 EKX38626.1 - 0.016 15.5 0.0 0.019 15.3 0.0 1.2 1 0 0 1 1 1 0 Rit1 DUSP-like domain HTH_Tnp_ISL3 PF13542.6 EKX38626.1 - 0.14 11.6 0.1 17 4.9 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 DFRP_C PF16543.5 EKX38627.1 - 1.2e-13 51.3 4.2 1.2e-13 51.3 4.2 3.8 2 2 2 4 4 4 1 DRG Family Regulatory Proteins, Tma46 Aldo_ket_red PF00248.21 EKX38629.1 - 6.5e-58 196.2 0.1 7.4e-58 196.1 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SMI1_KNR4 PF09346.10 EKX38630.1 - 0.0007 20.0 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_5 PF14567.6 EKX38630.1 - 0.043 13.5 0.0 0.2 11.4 0.0 1.9 1 1 0 1 1 1 0 SMI1-KNR4 cell-wall TIG PF01833.24 EKX38631.1 - 8.9e-15 54.5 5.4 6.4e-06 26.2 0.7 3.9 3 1 0 3 3 3 3 IPT/TIG domain EGF_2 PF07974.13 EKX38631.1 - 0.00014 22.1 8.0 0.00039 20.7 8.0 1.8 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 EKX38631.1 - 0.018 15.1 10.5 0.046 13.8 10.5 1.8 1 0 0 1 1 1 0 Tenascin EGF domain Caldesmon PF02029.15 EKX38631.1 - 0.057 12.2 28.7 0.0037 16.1 5.2 2.3 2 0 0 2 2 2 0 Caldesmon EGF PF00008.27 EKX38631.1 - 0.084 13.2 4.4 0.18 12.1 4.4 1.6 1 0 0 1 1 1 0 EGF-like domain Myc_target_1 PF15179.6 EKX38631.1 - 0.2 11.5 0.7 0.5 10.2 0.7 1.7 1 0 0 1 1 1 0 Myc target protein 1 HemY_N PF07219.13 EKX38631.1 - 0.3 11.3 13.1 0.68 10.1 0.7 3.4 3 0 0 3 3 3 0 HemY protein N-terminus Presenilin PF01080.17 EKX38631.1 - 0.39 9.4 10.8 2 7.1 2.0 3.0 3 0 0 3 3 3 0 Presenilin SDA1 PF05285.12 EKX38631.1 - 0.48 9.8 35.7 0.019 14.4 14.9 2.9 3 0 0 3 3 3 0 SDA1 DUF913 PF06025.12 EKX38631.1 - 0.96 8.4 4.9 1.4 7.8 1.4 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) I-EGF_1 PF18372.1 EKX38631.1 - 1 9.5 6.7 3.4 7.8 6.7 1.9 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 DUF4201 PF13870.6 EKX38632.1 - 1.2e-30 106.5 24.9 1.2e-30 106.5 24.9 3.2 2 2 0 2 2 2 1 Domain of unknown function (DUF4201) UDPGP PF01704.18 EKX38633.1 - 1.8e-19 69.7 0.0 1.8e-19 69.7 0.0 1.6 2 0 0 2 2 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4834 PF16118.5 EKX38633.1 - 0.00029 21.7 9.1 0.00082 20.3 9.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) Shisa PF13908.6 EKX38633.1 - 0.00074 19.8 9.2 0.0014 19.0 9.2 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator MMPL PF03176.15 EKX38633.1 - 0.04 12.9 5.1 0.11 11.4 5.1 1.7 1 0 0 1 1 1 0 MMPL family EphA2_TM PF14575.6 EKX38633.1 - 0.11 13.4 2.2 0.31 11.9 2.2 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SP_C-Propep PF08999.10 EKX38633.1 - 0.13 12.0 1.7 1.6 8.6 0.6 2.4 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide MID_MedPIWI PF18296.1 EKX38633.1 - 0.16 11.7 4.2 0.27 11.0 4.2 1.3 1 0 0 1 1 1 0 MID domain of medPIWI SCAI PF12070.8 EKX38633.1 - 0.31 9.9 3.7 0.52 9.1 3.7 1.2 1 0 0 1 1 1 0 Protein SCAI DUF2615 PF11027.8 EKX38633.1 - 0.77 9.9 4.6 0.7 10.1 0.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2615) Tmemb_9 PF05434.11 EKX38633.1 - 1.8 8.4 8.0 3.6 7.5 6.1 2.4 2 1 0 2 2 2 0 TMEM9 DUF4446 PF14584.6 EKX38633.1 - 2.3 8.2 5.8 4.9 7.1 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF2500 PF10694.9 EKX38633.1 - 2.6 8.6 5.9 6 7.4 5.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) Menin PF05053.13 EKX38633.1 - 3.1 6.1 6.4 4.5 5.5 6.4 1.1 1 0 0 1 1 1 0 Menin Ly49 PF08391.10 EKX38633.1 - 6.5 7.1 8.0 16 5.9 8.0 1.6 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region dUTPase PF00692.19 EKX38634.1 - 3.9e-41 139.7 0.0 6.1e-41 139.1 0.0 1.3 2 0 0 2 2 2 1 dUTPase TFIIB PF00382.19 EKX38635.1 - 1.1e-22 79.8 1.8 6e-11 42.2 0.4 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EKX38635.1 - 0.00018 21.0 0.4 0.0004 19.8 0.4 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding RB_B PF01857.20 EKX38635.1 - 0.058 13.4 0.3 0.16 12.0 0.1 1.7 1 1 1 2 2 2 0 Retinoblastoma-associated protein B domain Lar_restr_allev PF14354.6 EKX38635.1 - 0.12 12.7 1.8 0.2 12.1 0.3 2.0 2 0 0 2 2 2 0 Restriction alleviation protein Lar VEG PF06257.11 EKX38636.1 - 0.022 14.8 0.0 7.4 6.7 0.0 2.2 1 1 1 2 2 2 0 Biofilm formation stimulator VEG IGFBP PF00219.18 EKX38636.1 - 0.63 10.7 8.4 12 6.7 2.7 3.0 1 1 1 2 2 2 0 Insulin-like growth factor binding protein Defensin_3 PF08131.11 EKX38636.1 - 6.2 7.1 14.6 12 6.2 3.6 2.8 1 1 2 3 3 3 0 Defensin-like peptide family DUF4215 PF13948.6 EKX38637.1 - 3.2e-07 30.7 1.2 7.6e-07 29.5 1.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4215) fn3 PF00041.21 EKX38637.1 - 0.0011 19.3 2.5 2.1 8.7 0.1 3.6 3 0 0 3 3 3 2 Fibronectin type III domain ZU5 PF00791.20 EKX38637.1 - 0.029 14.7 0.1 0.14 12.5 0.1 2.2 1 0 0 1 1 1 0 ZU5 domain DUF2721 PF11026.8 EKX38638.1 - 0.018 14.9 0.1 0.018 14.9 0.1 6.8 5 2 2 7 7 7 0 Protein of unknown function (DUF2721) DUF3318 PF11780.8 EKX38638.1 - 0.18 11.8 0.3 2.3 8.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3318) SHR3_chaperone PF08229.11 EKX38638.1 - 1.2 8.1 10.3 0.054 12.5 1.4 3.0 3 0 0 3 3 3 0 ER membrane protein SH3 DZR PF12773.7 EKX38640.1 - 0.0047 16.9 7.3 0.026 14.5 7.7 2.0 1 1 1 2 2 2 2 Double zinc ribbon NOB1_Zn_bind PF08772.11 EKX38640.1 - 0.034 14.3 1.2 0.085 13.0 0.4 2.0 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Cyclin PF08613.11 EKX38641.1 - 7.5e-30 104.4 0.2 8.3e-29 101.0 0.1 1.9 1 1 1 2 2 2 1 Cyclin Cyclin_N PF00134.23 EKX38641.1 - 0.00023 20.9 0.0 0.00037 20.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain SLC35F PF06027.12 EKX38642.1 - 2.7e-57 194.6 21.4 2.8e-56 191.2 21.4 2.0 1 1 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 EKX38642.1 - 0.025 14.8 27.6 0.054 13.7 3.5 3.2 3 0 0 3 3 3 0 EamA-like transporter family CRT-like PF08627.10 EKX38642.1 - 0.24 10.3 8.2 0.25 10.2 6.7 2.0 1 1 0 1 1 1 0 CRT-like, chloroquine-resistance transporter-like Saf_2TM PF18303.1 EKX38642.1 - 0.88 9.1 3.8 16 5.1 0.9 2.5 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain TPT PF03151.16 EKX38644.1 - 1.6e-11 44.1 15.9 2.2e-11 43.7 15.9 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EKX38644.1 - 0.0003 21.0 29.4 0.00038 20.6 9.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EKX38644.1 - 0.00063 19.0 16.8 0.0014 18.0 16.7 1.5 1 1 0 1 1 1 1 UAA transporter family Connexin PF00029.19 EKX38645.1 - 0.051 13.3 0.1 0.064 13.0 0.1 1.1 1 0 0 1 1 1 0 Connexin DUF4337 PF14235.6 EKX38645.1 - 0.1 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Prominin PF05478.11 EKX38645.1 - 0.12 10.3 0.1 0.14 10.1 0.1 1.0 1 0 0 1 1 1 0 Prominin Upf2 PF04050.14 EKX38646.1 - 1.8 9.3 7.7 0.67 10.7 0.3 3.1 3 0 0 3 3 3 0 Up-frameshift suppressor 2 Rieske_2 PF13806.6 EKX38647.1 - 0.0023 17.8 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 EKX38647.1 - 0.033 14.1 0.0 0.077 12.9 0.0 1.6 1 1 0 1 1 1 0 Rieske [2Fe-2S] domain C2-set_2 PF08205.12 EKX38648.1 - 0.048 13.7 1.1 2.3 8.3 0.0 2.9 3 0 0 3 3 3 0 CD80-like C2-set immunoglobulin domain Ubiq-assoc PF09145.10 EKX38648.1 - 0.14 12.1 0.7 11 6.1 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-associated MORN_2 PF07661.13 EKX38648.1 - 0.39 11.1 2.3 23 5.6 0.3 2.6 2 0 0 2 2 2 0 MORN repeat variant BH4 PF02180.17 EKX38648.1 - 3 7.8 5.1 7.8 6.4 0.3 2.4 2 0 0 2 2 2 0 Bcl-2 homology region 4 DUF4215 PF13948.6 EKX38649.1 - 1.1e-07 32.2 1.6 2.4e-07 31.1 1.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4215) ZU5 PF00791.20 EKX38649.1 - 0.032 14.6 0.1 0.15 12.4 0.1 2.2 1 0 0 1 1 1 0 ZU5 domain HrpB2 PF09487.10 EKX38649.1 - 0.32 11.4 4.5 1.5 9.3 4.5 2.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) BES1_N PF05687.13 EKX38650.1 - 2.5 8.5 12.0 0.16 12.4 1.3 2.6 2 0 0 2 2 2 0 BES1/BZR1 plant transcription factor, N-terminal Lebercilin PF15619.6 EKX38652.1 - 0.0019 17.9 6.6 0.0019 17.9 6.6 2.8 2 1 1 3 3 3 2 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 EKX38652.1 - 0.0078 15.1 9.9 0.015 14.2 9.9 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Bacillus_HBL PF05791.11 EKX38652.1 - 0.15 11.9 1.9 0.26 11.1 1.9 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) ADIP PF11559.8 EKX38652.1 - 0.34 11.0 7.7 0.84 9.7 7.5 1.8 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding FliJ PF02050.16 EKX38652.1 - 0.42 10.9 9.7 3.7 7.8 9.7 2.4 1 1 1 2 2 2 0 Flagellar FliJ protein PKcGMP_CC PF16808.5 EKX38652.1 - 0.86 9.5 7.0 2.7 7.9 0.3 3.5 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase THOC7 PF05615.13 EKX38652.1 - 1.6 9.1 9.9 1.9 8.8 8.0 1.9 2 0 0 2 2 2 0 Tho complex subunit 7 DUF1192 PF06698.11 EKX38652.1 - 4 7.6 9.9 1.9 8.6 0.5 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) DivIC PF04977.15 EKX38652.1 - 4.5 7.1 9.4 3.5 7.5 1.1 2.8 1 1 1 2 2 2 0 Septum formation initiator Pox_A_type_inc PF04508.12 EKX38652.1 - 7.6 6.6 8.2 1 9.3 2.4 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat SWIB PF02201.18 EKX38653.1 - 1.5e-27 95.2 0.0 4e-27 93.9 0.0 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 EKX38653.1 - 2.1e-10 40.3 2.1 1.1e-09 38.1 0.6 2.3 2 0 0 2 2 2 1 DEK C terminal domain eIF-3c_N PF05470.12 EKX38653.1 - 0.0072 14.7 0.4 0.0072 14.7 0.4 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF3348 PF11828.8 EKX38653.1 - 0.072 12.8 0.7 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3348) SAPS PF04499.15 EKX38653.1 - 1.4 7.7 8.2 1.6 7.4 8.2 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein FAM176 PF14851.6 EKX38653.1 - 1.6 8.4 19.1 0.097 12.3 2.5 3.2 3 0 0 3 3 3 0 FAM176 family DNA_pol_phi PF04931.13 EKX38653.1 - 2.2 6.3 33.6 0.012 13.8 9.6 2.2 1 1 1 2 2 2 0 DNA polymerase phi ORC_WH_C PF18137.1 EKX38653.1 - 7 6.7 21.2 0.087 12.9 3.7 3.0 3 0 0 3 3 3 0 Origin recognition complex winged helix C-terminal Nop53 PF07767.11 EKX38654.1 - 2.9e-41 142.2 43.6 1.4e-22 80.7 26.5 2.1 2 0 0 2 2 2 2 Nop53 (60S ribosomal biogenesis) RL PF17797.1 EKX38654.1 - 0.044 13.7 0.5 0.12 12.3 0.5 1.8 1 0 0 1 1 1 0 RL domain NAPRTase_C PF17956.1 EKX38654.1 - 0.2 12.1 3.0 11 6.4 1.1 2.5 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase C-terminal domain HAD_SAK_2 PF18143.1 EKX38655.1 - 3e-17 63.2 0.5 4.7e-16 59.4 0.5 2.0 1 1 0 1 1 1 1 HAD domain in Swiss Army Knife RNA repair proteins Complex1_LYR PF05347.15 EKX38656.1 - 4.1e-07 29.9 0.2 5e-07 29.7 0.2 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 EKX38656.1 - 0.036 14.7 0.0 0.039 14.6 0.0 1.2 1 0 0 1 1 1 0 Complex1_LYR-like ubiquitin PF00240.23 EKX38657.1 - 4.5e-22 77.6 0.1 2.3e-12 46.5 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 EKX38657.1 - 1.6e-05 24.7 0.3 7.2e-05 22.5 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Big_5 PF13205.6 EKX38657.1 - 0.00018 22.2 0.0 0.043 14.5 0.0 2.7 2 1 0 2 2 2 1 Bacterial Ig-like domain TBK1_ULD PF18396.1 EKX38657.1 - 0.11 12.5 0.0 16 5.5 0.0 2.4 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain Asp PF00026.23 EKX38660.1 - 3e-12 46.6 0.0 5.9e-08 32.5 0.1 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EKX38660.1 - 5.2e-05 23.6 0.0 7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Phage_holin_2_4 PF16082.5 EKX38660.1 - 0.0016 18.2 0.1 0.0027 17.4 0.1 1.3 1 0 0 1 1 1 1 Bacteriophage holin family, superfamily II-like Phage_holin_2_3 PF16080.5 EKX38660.1 - 0.024 14.4 0.0 0.065 13.0 0.0 1.8 1 0 0 1 1 1 0 Bacteriophage holin family HP1 PHD PF00628.29 EKX38661.1 - 2e-13 50.0 6.7 3.1e-13 49.4 6.7 1.3 1 0 0 1 1 1 1 PHD-finger C1_2 PF03107.16 EKX38661.1 - 0.0067 16.7 4.1 0.037 14.4 1.7 2.2 2 0 0 2 2 2 1 C1 domain zf_UBZ PF18439.1 EKX38661.1 - 0.033 13.8 0.7 0.17 11.5 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-ANAPC11 PF12861.7 EKX38661.1 - 0.06 13.4 2.5 0.09 12.8 2.5 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RanBP PF00641.18 EKX38661.1 - 0.062 12.6 0.7 0.062 12.6 0.7 2.4 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others Zf_RING PF16744.5 EKX38661.1 - 0.17 12.1 10.3 5.3 7.2 8.1 3.1 1 1 1 2 2 2 0 KIAA1045 RING finger zf-HC5HC2H PF13771.6 EKX38661.1 - 0.25 11.6 3.5 0.5 10.7 3.5 1.6 1 1 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 EKX38661.1 - 0.65 9.6 8.0 0.26 10.9 4.1 2.3 2 1 0 2 2 2 0 PHD-finger C1_1 PF00130.22 EKX38661.1 - 0.76 9.7 6.3 2.6 8.0 1.9 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYVE PF01363.21 EKX38661.1 - 1.5 9.0 7.5 12 6.1 0.9 2.8 1 1 1 2 2 2 0 FYVE zinc finger PhyH PF05721.13 EKX38662.1 - 9.2e-09 35.9 0.1 9.2e-09 35.9 0.1 1.7 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) Glutaredoxin PF00462.24 EKX38663.1 - 6.9e-10 39.0 0.0 1.2e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Lactamase_B_6 PF16661.5 EKX38664.1 - 2.3e-58 196.8 0.0 4.9e-58 195.7 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 EKX38664.1 - 2.1e-19 70.3 7.1 3.7e-17 63.0 0.0 3.2 2 1 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 EKX38664.1 - 1.7e-13 50.8 0.0 4e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 EKX38664.1 - 1.9e-10 41.1 0.0 5e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 EKX38664.1 - 1.8e-08 34.2 0.0 4.6e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 EKX38664.1 - 5.5e-06 26.0 0.0 2.1e-05 24.1 0.0 2.0 3 0 0 3 3 3 1 Beta-lactamase superfamily domain Paf1 PF03985.13 EKX38664.1 - 0.035 13.1 9.3 0.052 12.5 9.3 1.2 1 0 0 1 1 1 0 Paf1 DUF1541 PF07563.11 EKX38664.1 - 0.14 12.1 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) CDC45 PF02724.14 EKX38664.1 - 0.74 8.0 5.1 1.1 7.5 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1682 PF07946.14 EKX38664.1 - 1.5 7.9 5.0 2.5 7.2 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Abhydrolase_6 PF12697.7 EKX38665.1 - 2e-09 38.4 0.0 2.5e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EKX38665.1 - 0.00072 19.7 0.1 0.0013 18.9 0.1 1.5 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 EKX38665.1 - 0.0022 17.7 0.0 0.0048 16.6 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EKX38665.1 - 0.0056 16.0 0.0 0.009 15.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 EKX38665.1 - 0.0074 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Ser_hydrolase PF06821.13 EKX38665.1 - 0.0098 15.8 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 Serine hydrolase PGAP1 PF07819.13 EKX38665.1 - 0.03 14.0 0.2 0.05 13.3 0.2 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.7 EKX38665.1 - 0.071 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 EKX38665.1 - 0.088 11.7 0.4 0.14 11.1 0.0 1.4 2 0 0 2 2 2 0 Chlorophyllase enzyme Esterase PF00756.20 EKX38665.1 - 0.088 12.4 0.0 2.4 7.7 0.0 2.1 2 0 0 2 2 2 0 Putative esterase EF-hand_1 PF00036.32 EKX38666.1 - 6.6e-08 31.6 0.9 2.3e-05 23.6 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX38666.1 - 4.3e-06 26.2 0.6 0.0001 22.0 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 EKX38666.1 - 0.00014 21.2 1.1 0.0022 17.4 0.4 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EKX38666.1 - 0.00024 21.5 1.9 0.00069 20.0 1.4 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EKX38666.1 - 0.0045 16.8 0.6 0.19 11.6 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain pair ORMDL PF04061.14 EKX38668.1 - 2.1e-32 111.8 2.0 2.7e-32 111.4 2.0 1.1 1 0 0 1 1 1 1 ORMDL family Pkinase PF00069.25 EKX38669.1 - 2.9e-55 187.5 0.0 4.9e-55 186.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX38669.1 - 8.3e-42 143.3 0.0 1.9e-41 142.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX38669.1 - 9.2e-05 21.4 0.0 0.00015 20.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EKX38669.1 - 0.00018 21.0 0.0 0.00032 20.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EKX38669.1 - 0.00041 20.0 0.3 0.18 11.4 0.1 2.6 2 1 1 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Ribosomal_L6e PF01159.19 EKX38670.1 - 1.1e-34 119.3 1.0 2e-34 118.4 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L6e SMC_Nse1 PF07574.13 EKX38671.1 - 2.1e-08 34.3 0.0 2.8e-07 30.6 0.0 2.2 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex HTH_27 PF13463.6 EKX38671.1 - 0.025 15.1 0.0 0.066 13.7 0.0 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain Peptidase_M41 PF01434.18 EKX38672.1 - 0.0037 17.1 0.1 1.1 9.1 0.0 2.8 3 0 0 3 3 3 2 Peptidase family M41 NUMOD4 PF07463.11 EKX38673.1 - 0.0043 17.2 0.0 0.33 11.2 0.0 2.4 2 0 0 2 2 2 2 NUMOD4 motif CENP-B_N PF04218.13 EKX38673.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain NUMOD4 PF07463.11 EKX38674.1 - 0.0038 17.4 0.0 0.31 11.3 0.0 2.4 2 0 0 2 2 2 2 NUMOD4 motif CENP-B_N PF04218.13 EKX38674.1 - 0.12 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain CENP-B_N PF04218.13 EKX38675.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Lipase_3 PF01764.25 EKX38677.1 - 1.6e-07 31.3 0.2 1.3e-06 28.4 0.1 2.0 2 0 0 2 2 2 1 Lipase (class 3) Peptidase_C1 PF00112.23 EKX38678.1 - 3e-25 89.6 2.8 3.2e-25 89.5 2.8 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EKX38678.1 - 0.00021 20.2 0.8 0.00023 20.1 0.8 1.0 1 0 0 1 1 1 1 Peptidase C1-like family CH PF00307.31 EKX38680.1 - 1.7e-07 31.4 0.0 8.6e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 Calponin homology (CH) domain Methyltransf_22 PF13383.6 EKX38681.1 - 2.6e-16 60.0 0.0 4.2e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 EKX38681.1 - 5.2e-08 33.1 0.1 1.6e-07 31.5 0.2 1.7 1 1 1 2 2 2 1 Methyltransferase FkbM domain DUF4392 PF14336.6 EKX38682.1 - 1.9e-83 280.3 0.0 2.6e-83 279.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) YjeF_N PF03853.15 EKX38682.1 - 0.09 12.7 0.0 2.7 7.8 0.0 2.3 2 0 0 2 2 2 0 YjeF-related protein N-terminus Pkinase PF00069.25 EKX38683.1 - 9.1e-61 205.5 1.8 9.9e-61 205.4 0.1 1.7 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX38683.1 - 1.7e-34 119.3 0.2 6.1e-34 117.5 0.1 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX38683.1 - 0.00054 19.4 0.0 0.00092 18.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EKX38683.1 - 0.0031 17.1 0.9 0.0031 17.1 0.9 2.3 2 1 0 2 2 2 1 RIO1 family APH PF01636.23 EKX38683.1 - 0.039 13.9 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Phage_Orf51 PF06194.11 EKX38683.1 - 0.083 12.9 0.6 12 6.0 0.0 3.2 2 1 1 3 3 3 0 Phage Conserved Open Reading Frame 51 YukC PF10140.9 EKX38683.1 - 0.11 11.3 0.1 0.11 11.3 0.1 2.4 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukC HALZ PF02183.18 EKX38683.1 - 1.2 9.5 5.5 3.9 7.8 0.5 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF5320 PF17253.2 EKX38683.1 - 2 9.5 3.9 7 7.8 0.2 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DUF2951 PF11166.8 EKX38683.1 - 3.1 8.1 6.8 1.6 9.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) DUF3450 PF11932.8 EKX38683.1 - 3.5 6.9 6.2 3.3 7.0 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) PX PF00787.24 EKX38684.1 - 3.9e-09 36.5 0.0 9.3e-09 35.3 0.0 1.6 2 0 0 2 2 2 1 PX domain Sugar_tr PF00083.24 EKX38686.1 - 7.9e-33 114.0 15.9 1.2e-32 113.4 15.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EKX38686.1 - 1.1e-19 70.6 37.6 1.5e-10 40.6 22.1 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily DNA_topoisoIV PF00521.20 EKX38687.1 - 1.4e-129 432.7 0.2 8.5e-129 430.2 0.0 2.0 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EKX38687.1 - 4.9e-49 165.9 0.4 1.6e-48 164.2 0.4 2.0 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EKX38687.1 - 3e-24 85.5 0.2 6.1e-24 84.4 0.2 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 EKX38687.1 - 8.6e-14 52.0 0.0 2.6e-13 50.5 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EKX38687.1 - 4.8e-06 26.7 0.0 1.8e-05 24.9 0.0 2.0 1 0 0 1 1 1 1 Toprim domain TBK1_ULD PF18396.1 EKX38688.1 - 6.2e-05 22.8 0.1 0.00011 22.1 0.1 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain ubiquitin PF00240.23 EKX38688.1 - 0.0013 18.5 0.1 0.0021 17.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_4 PF18036.1 EKX38688.1 - 0.023 14.7 0.1 0.04 14.0 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain SAM_4 PF18017.1 EKX38688.1 - 0.072 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) LRR_8 PF13855.6 EKX38690.1 - 4.1e-114 372.4 131.9 1.5e-16 59.9 8.6 10.2 1 1 9 11 11 11 11 Leucine rich repeat LRR_4 PF12799.7 EKX38690.1 - 1.9e-71 234.7 84.0 1.7e-08 34.6 4.4 12.0 5 2 6 14 14 14 14 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX38690.1 - 4.2e-31 107.6 19.2 4.2e-11 42.9 0.4 5.6 1 1 3 5 5 5 4 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EKX38690.1 - 3.4e-29 96.9 62.6 0.23 12.1 0.3 19.9 19 1 0 19 19 19 9 Leucine Rich Repeat LRR_9 PF14580.6 EKX38690.1 - 8.5e-19 67.7 23.2 6.3e-05 22.5 0.6 6.1 1 1 5 7 7 7 7 Leucine-rich repeat LRR_6 PF13516.6 EKX38690.1 - 1.3e-17 62.3 104.3 0.28 11.3 0.5 19.1 19 0 0 19 19 19 11 Leucine Rich repeat Aldolase PF01081.19 EKX38690.1 - 0.00032 20.2 0.0 13 5.2 0.0 4.1 2 1 2 5 5 5 1 KDPG and KHG aldolase LRRNT PF01462.18 EKX38690.1 - 0.026 14.2 2.7 3.9e+02 0.8 0.0 7.6 9 0 0 9 9 9 0 Leucine rich repeat N-terminal domain DUF5568 PF17724.1 EKX38690.1 - 0.13 12.0 0.3 10 5.9 0.0 3.6 4 0 0 4 4 4 0 Family of unknown function (DUF5568) GIT_SHD PF08518.11 EKX38690.1 - 0.19 11.4 0.3 42 3.9 0.0 3.9 3 0 0 3 3 3 0 Spa2 homology domain (SHD) of GIT CBM_X2 PF03442.14 EKX38690.1 - 2.1 8.6 11.5 26 5.0 0.4 5.0 3 2 2 5 5 5 0 Carbohydrate binding domain X2 PAC3 PF10178.9 EKX38691.1 - 5.8e-17 61.6 0.1 7.3e-17 61.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 POC3_POC4 PF10448.9 EKX38691.1 - 0.0049 16.9 0.3 0.041 13.9 0.3 2.0 1 1 0 1 1 1 1 20S proteasome chaperone assembly proteins 3 and 4 cNMP_binding PF00027.29 EKX38692.1 - 0.00035 20.6 0.1 0.017 15.2 0.1 2.4 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain Phage_TAC_11 PF11836.8 EKX38692.1 - 0.098 12.8 0.1 0.21 11.7 0.1 1.6 1 0 0 1 1 1 0 Phage tail tube protein, GTA-gp10 TetR_C_14 PF17754.1 EKX38693.1 - 0.033 14.1 1.3 5.9 6.9 0.0 2.6 2 0 0 2 2 2 0 MftR C-terminal domain His_Phos_1 PF00300.22 EKX38694.1 - 8.9e-37 126.7 0.0 1.5e-28 99.9 0.0 2.2 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF3235 PF11574.8 EKX38694.1 - 3 8.8 0.0 3 8.8 0.0 4.7 3 1 2 5 5 5 0 Protein of unknown function (DUF3235) PDZ_6 PF17820.1 EKX38695.1 - 1.1e-06 28.3 0.0 1.9e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX38695.1 - 0.0024 18.1 0.0 0.0045 17.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX38695.1 - 0.0035 17.7 0.0 0.0057 17.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX38695.1 - 0.048 13.6 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 Tricorn protease PDZ domain Ank_5 PF13857.6 EKX38696.1 - 8.1e-12 45.1 1.2 2.2e-06 27.8 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX38696.1 - 3.4e-11 42.3 0.1 0.002 18.5 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EKX38696.1 - 4.2e-11 43.3 0.0 8.5e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX38696.1 - 1.3e-10 41.3 0.2 0.00096 19.5 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EKX38696.1 - 3.3e-10 40.3 0.7 2.9e-09 37.3 0.1 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) LRR_8 PF13855.6 EKX38697.1 - 2.8e-24 84.6 51.1 2.2e-07 30.6 5.0 4.9 1 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 EKX38697.1 - 6e-24 83.7 27.9 1.6e-05 25.2 1.1 5.6 2 1 5 7 7 7 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX38697.1 - 4.4e-08 32.8 7.7 0.00055 19.5 1.9 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 EKX38697.1 - 0.00028 20.7 24.7 0.14 12.3 0.1 7.6 7 1 0 7 7 7 1 Leucine Rich repeat LRR_1 PF00560.33 EKX38697.1 - 0.00096 19.4 25.1 1.2 10.0 0.1 7.9 6 2 0 6 6 6 3 Leucine Rich Repeat LRR_5 PF13306.6 EKX38697.1 - 0.018 15.0 1.0 0.64 10.0 0.3 2.4 1 1 1 2 2 2 0 BspA type Leucine rich repeat region (6 copies) RPAP3_C PF13877.6 EKX38699.1 - 1.4e-14 54.4 0.4 5.3e-14 52.5 0.0 2.1 2 0 0 2 2 2 1 Potential Monad-binding region of RPAP3 TPR_2 PF07719.17 EKX38699.1 - 1.6e-11 43.4 4.1 1.3e-06 28.0 1.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX38699.1 - 2e-10 40.6 2.5 2.9e-05 24.1 3.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX38699.1 - 2.2e-09 36.7 1.0 5.4e-06 26.0 0.3 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Dynein_attach_N PF15867.5 EKX38699.1 - 8.1e-08 32.1 1.2 8.1e-08 32.1 1.2 2.6 3 0 0 3 3 2 1 Dynein attachment factor N-terminus TPR_11 PF13414.6 EKX38699.1 - 1.3e-07 31.1 0.3 0.0089 15.7 0.5 2.4 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 EKX38699.1 - 2.6e-07 30.3 0.7 0.00023 21.1 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX38699.1 - 1.5e-06 28.8 4.4 0.0012 19.5 5.4 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX38699.1 - 0.00023 21.7 5.4 0.002 18.8 2.6 3.4 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX38699.1 - 0.0077 16.2 0.3 0.038 14.0 0.3 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX38699.1 - 0.016 15.5 1.2 0.14 12.4 0.4 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX38699.1 - 0.027 15.1 2.6 0.33 11.7 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EKX38699.1 - 0.067 13.8 1.8 0.25 12.1 1.8 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX38699.1 - 0.31 11.6 5.9 1.6 9.3 1.7 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat CENP-N PF05238.13 EKX38699.1 - 0.45 9.8 6.5 0.88 8.8 6.5 1.4 1 0 0 1 1 1 0 Kinetochore protein CHL4 like AAA_11 PF13086.6 EKX38699.1 - 3.5 7.4 9.2 5.7 6.6 9.2 1.3 1 0 0 1 1 1 0 AAA domain MAJIN PF15077.6 EKX38699.1 - 9.4 5.9 10.1 19 4.9 9.4 1.8 1 1 0 1 1 1 0 Membrane-anchored junction protein TMEM70 PF06979.12 EKX38701.1 - 8.6e-16 58.6 0.0 1.6e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex TPR_17 PF13431.6 EKX38701.1 - 0.0014 18.8 0.0 0.0029 17.9 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat RWP-RK PF02042.15 EKX38702.1 - 7.4e-14 51.5 0.2 1.8e-13 50.2 0.1 1.6 2 0 0 2 2 2 1 RWP-RK domain DrrA_P4M PF14860.6 EKX38703.1 - 4.9 7.1 12.1 0.052 13.4 3.7 2.0 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain Brix PF04427.18 EKX38704.1 - 7.9e-33 114.2 0.2 1e-32 113.8 0.2 1.1 1 0 0 1 1 1 1 Brix domain DnaJ_C PF01556.18 EKX38705.1 - 1.1e-35 122.9 0.8 1.5e-35 122.4 0.8 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EKX38705.1 - 1.3e-17 63.6 0.1 2.1e-17 63.0 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Ribosomal_S26e PF01283.19 EKX38705.1 - 0.2 12.1 3.9 0.38 11.2 3.9 1.5 1 0 0 1 1 1 0 Ribosomal protein S26e DHHC PF01529.20 EKX38705.1 - 1.8 8.7 5.0 2.7 8.1 5.0 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Mito_carr PF00153.27 EKX38706.1 - 1.4e-08 34.5 0.0 8.1e-07 28.9 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF4551 PF15087.6 EKX38707.1 - 2 7.1 6.0 2.6 6.8 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) BCCT PF02028.17 EKX38708.1 - 6.7e-102 341.4 28.2 8.1e-102 341.2 28.2 1.0 1 0 0 1 1 1 1 BCCT, betaine/carnitine/choline family transporter SSXT PF05030.12 EKX38710.1 - 5.9e-18 64.3 2.9 5.9e-18 64.3 2.9 2.1 2 0 0 2 2 2 1 SSXT protein (N-terminal region) Myb_DNA-binding PF00249.31 EKX38710.1 - 1.6e-06 28.2 0.1 5.4e-06 26.5 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EKX38710.1 - 0.019 14.8 0.3 0.052 13.4 0.0 1.8 2 0 0 2 2 2 0 Myb DNA-binding like Elf4 PF07011.11 EKX38710.1 - 0.03 14.2 1.9 0.057 13.3 1.4 1.7 1 1 0 1 1 1 0 Early Flowering 4 domain Myb_DNA-bind_6 PF13921.6 EKX38710.1 - 0.037 14.3 0.3 0.096 13.0 0.3 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF5526 PF17664.1 EKX38710.1 - 0.39 10.3 3.0 0.19 11.3 0.7 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5526) MMADHC PF10229.9 EKX38711.1 - 0.045 13.5 0.1 0.061 13.1 0.1 1.2 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type D protein Pkinase PF00069.25 EKX38712.1 - 9.7e-37 126.7 0.0 4.3e-35 121.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX38712.1 - 2.8e-27 95.6 0.0 6.3e-26 91.2 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX38712.1 - 0.011 15.6 0.1 0.036 14.0 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family ABC1 PF03109.16 EKX38712.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 ABC1 family BNIP3 PF06553.12 EKX38713.1 - 0.15 11.7 3.1 0.24 11.0 3.1 1.3 1 0 0 1 1 1 0 BNIP3 PDZ_2 PF13180.6 EKX38714.1 - 8.3e-07 29.2 0.0 2.6e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 PDZ domain TolA_bind_tri PF16331.5 EKX38714.1 - 0.00032 20.7 2.0 0.00032 20.7 2.0 5.7 4 2 0 4 4 4 1 TolA binding protein trimerisation PDZ_6 PF17820.1 EKX38714.1 - 0.092 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 PDZ domain CPG4 PF15481.6 EKX38714.1 - 0.13 12.9 3.3 4.8 7.9 0.2 3.4 2 0 0 2 2 2 0 Chondroitin proteoglycan 4 FliD_N PF02465.18 EKX38714.1 - 2.3 9.0 22.5 0.58 10.9 2.4 4.8 3 1 1 4 4 4 0 Flagellar hook-associated protein 2 N-terminus EzrA PF06160.12 EKX38714.1 - 2.9 6.0 53.9 3.6 5.6 22.3 3.0 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA EB1 PF03271.17 EKX38715.1 - 5.8e-12 45.7 0.0 1.5e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 EKX38715.1 - 7.1e-08 32.6 0.0 1.8e-07 31.3 0.0 1.6 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EKX38715.1 - 0.0037 17.1 0.0 0.0062 16.3 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain Suppressor_APC PF11414.8 EKX38715.1 - 0.019 15.0 0.2 0.038 14.1 0.2 1.4 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein CCDC106 PF15794.5 EKX38715.1 - 0.15 11.8 0.1 0.25 11.0 0.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Abhydrolase_1 PF00561.20 EKX38716.1 - 1.4e-15 57.7 0.5 1.9e-15 57.2 0.5 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EKX38716.1 - 4.6e-13 49.0 0.0 6.6e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EKX38716.1 - 6.6e-10 40.0 0.0 9.3e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EKX38716.1 - 7.6e-05 22.6 1.1 0.3 10.9 0.1 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Palm_thioest PF02089.15 EKX38716.1 - 0.0037 17.1 0.0 0.0045 16.8 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Peptidase_S9 PF00326.21 EKX38716.1 - 0.0087 15.6 0.2 0.016 14.6 0.2 1.5 1 1 1 2 2 2 1 Prolyl oligopeptidase family Ndr PF03096.14 EKX38716.1 - 0.016 13.9 0.0 0.037 12.7 0.0 1.6 2 0 0 2 2 2 0 Ndr family Chlorophyllase2 PF12740.7 EKX38716.1 - 0.059 12.3 0.0 0.097 11.6 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Esterase PF00756.20 EKX38716.1 - 0.061 13.0 0.0 0.13 11.9 0.0 1.5 2 0 0 2 2 2 0 Putative esterase DUF915 PF06028.11 EKX38716.1 - 0.15 11.3 0.0 3.3 7.0 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.13 EKX38716.1 - 0.44 10.2 0.9 0.52 10.0 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein Thioredoxin PF00085.20 EKX38717.1 - 1.3e-38 131.1 0.3 2.7e-22 78.7 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin Glyco_transf_41 PF13844.6 EKX38717.1 - 2.9e-10 39.2 0.0 4.6e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 41 Thioredoxin_7 PF13899.6 EKX38717.1 - 2e-09 37.5 0.1 0.00013 22.1 0.0 3.3 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EKX38717.1 - 9.6e-08 32.5 0.4 0.00031 21.2 0.1 3.4 3 1 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EKX38717.1 - 1.9e-07 30.8 0.0 0.00011 21.7 0.0 2.5 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_6 PF13848.6 EKX38717.1 - 1.6e-06 28.1 0.2 0.00033 20.6 0.1 3.1 2 1 1 3 3 3 1 Thioredoxin-like domain AhpC-TSA PF00578.21 EKX38717.1 - 2.2e-06 27.6 0.4 0.002 18.0 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_8 PF13905.6 EKX38717.1 - 5.2e-06 26.7 0.0 0.07 13.5 0.0 3.4 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_3 PF13192.6 EKX38717.1 - 0.0059 16.6 0.0 0.043 13.9 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin domain YopD PF05844.12 EKX38717.1 - 0.091 11.8 0.9 0.14 11.1 0.9 1.2 1 0 0 1 1 1 0 YopD protein Thioredoxin_4 PF13462.6 EKX38717.1 - 0.11 12.7 0.6 3.2 7.9 0.1 2.5 2 0 0 2 2 2 0 Thioredoxin DUF2834 PF11196.8 EKX38718.1 - 0.011 16.1 0.4 0.011 16.1 0.4 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2834) GBV-C_env PF12786.7 EKX38718.1 - 0.11 11.2 0.2 0.14 10.8 0.2 1.2 1 0 0 1 1 1 0 GB virus C genotype envelope C_GCAxxG_C_C PF09719.10 EKX38718.1 - 0.16 12.3 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) Met_10 PF02475.16 EKX38719.1 - 3.3e-35 121.7 0.1 1.2e-33 116.6 0.0 2.8 2 1 0 2 2 2 1 Met-10+ like-protein FHA PF00498.26 EKX38720.1 - 3.6e-08 33.6 1.1 2.1e-07 31.2 0.1 3.0 3 0 0 3 3 3 1 FHA domain DUF883 PF05957.13 EKX38720.1 - 0.022 15.4 7.1 0.083 13.5 7.1 2.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DivIVA PF05103.13 EKX38720.1 - 0.059 13.5 8.7 0.17 12.0 8.7 1.7 1 0 0 1 1 1 0 DivIVA protein NIF PF03031.18 EKX38720.1 - 0.064 13.0 0.0 0.39 10.5 0.0 2.2 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase Indigoidine_A PF04227.12 EKX38720.1 - 0.11 11.9 0.2 0.19 11.0 0.2 1.3 1 0 0 1 1 1 0 Indigoidine synthase A like protein Remorin_C PF03763.13 EKX38720.1 - 2 8.4 11.4 0.34 10.8 7.1 2.0 2 0 0 2 2 2 0 Remorin, C-terminal region YtxH PF12732.7 EKX38720.1 - 4.4 7.9 6.2 12 6.5 6.2 1.8 1 0 0 1 1 1 0 YtxH-like protein JAKMIP_CC3 PF16034.5 EKX38721.1 - 0.017 15.0 3.4 0.022 14.7 3.4 1.1 1 0 0 1 1 1 0 JAKMIP CC3 domain TFIIS_C PF01096.18 EKX38722.1 - 5.5e-18 64.5 1.7 5.5e-18 64.5 1.7 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EKX38722.1 - 5.8e-08 32.5 0.9 5.8e-08 32.5 0.9 2.5 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 EKX38722.1 - 4.3e-05 23.4 7.3 0.0055 16.7 1.0 2.3 2 0 0 2 2 2 2 Transposase zinc-ribbon domain Nudix_N_2 PF14803.6 EKX38722.1 - 0.026 14.4 4.1 5.3 7.0 0.0 2.9 2 1 0 2 2 2 0 Nudix N-terminal zf-ISL3 PF14690.6 EKX38722.1 - 0.15 12.7 3.5 6.7 7.5 0.0 3.2 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Lar_restr_allev PF14354.6 EKX38722.1 - 0.16 12.3 5.0 0.6 10.5 0.6 2.2 2 0 0 2 2 2 0 Restriction alleviation protein Lar OrfB_Zn_ribbon PF07282.11 EKX38722.1 - 0.72 9.8 4.4 13 5.8 0.4 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain TF_Zn_Ribbon PF08271.12 EKX38722.1 - 3.1 7.4 7.6 8.8 5.9 0.8 2.6 2 1 0 2 2 2 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 EKX38722.1 - 6.5 6.3 13.4 3.3 7.3 2.2 3.1 3 0 0 3 3 3 0 zinc-ribbon domain SNAP PF14938.6 EKX38723.1 - 2.6e-20 73.0 11.6 2.6e-20 73.0 11.6 2.0 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 EKX38723.1 - 3.6e-06 27.2 7.5 0.00045 20.5 1.4 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX38723.1 - 0.00025 20.9 4.2 0.62 10.2 0.0 4.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX38723.1 - 0.00079 19.4 9.0 0.64 10.3 0.1 5.2 4 1 2 6 6 6 1 Tetratricopeptide repeat GAIN PF16489.5 EKX38723.1 - 0.0073 15.7 0.2 0.016 14.6 0.2 1.5 1 0 0 1 1 1 1 GPCR-Autoproteolysis INducing (GAIN) domain TPR_8 PF13181.6 EKX38723.1 - 0.023 14.9 13.3 2 8.8 2.3 4.7 3 1 2 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 EKX38723.1 - 0.03 14.5 0.7 0.25 11.7 0.0 3.0 3 0 0 3 3 3 0 PPR repeat TPR_6 PF13174.6 EKX38723.1 - 0.031 14.9 6.2 32 5.4 0.1 5.1 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX38723.1 - 0.094 13.6 9.5 6.7 7.8 0.0 5.0 4 2 2 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX38723.1 - 0.18 11.7 5.6 9.3 6.3 0.4 4.5 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EKX38723.1 - 0.28 10.9 8.6 2.2 8.0 0.1 4.4 4 1 1 5 5 5 0 TPR repeat PPR_2 PF13041.6 EKX38723.1 - 0.38 11.0 2.3 3.4 7.9 0.1 3.3 4 0 0 4 4 4 0 PPR repeat family TPR_1 PF00515.28 EKX38723.1 - 1.1 9.2 11.1 0.38 10.6 0.2 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 EKX38723.1 - 6 7.0 10.2 3.5 7.8 0.3 3.5 3 1 0 4 4 3 0 MIT (microtubule interacting and transport) domain T2SSF PF00482.23 EKX38724.1 - 0.84 9.6 4.1 0.45 10.5 0.8 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Exo_endo_phos PF03372.23 EKX38725.1 - 0.00099 18.7 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.27 EKX38726.1 - 1.8e-08 34.2 0.1 3.5e-08 33.3 0.1 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Arf PF00025.21 EKX38727.1 - 3.8e-58 195.8 0.0 5.3e-58 195.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EKX38727.1 - 2.1e-11 43.7 0.0 3.8e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EKX38727.1 - 4.4e-11 42.5 0.0 7.6e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EKX38727.1 - 1.2e-10 41.7 0.0 2e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EKX38727.1 - 4.8e-05 22.7 0.0 0.001 18.3 0.0 2.2 1 1 1 2 2 2 1 G-protein alpha subunit Gtr1_RagA PF04670.12 EKX38727.1 - 7.5e-05 22.2 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SET PF00856.28 EKX38728.1 - 4e-06 27.3 0.9 1.3e-05 25.6 0.1 2.0 2 1 0 2 2 2 1 SET domain YoaP PF14268.6 EKX38728.1 - 0.18 11.3 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 YoaP-like RNase_Zc3h12a PF11977.8 EKX38729.1 - 5.1e-09 36.1 0.0 1.2e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain SUIM_assoc PF16619.5 EKX38729.1 - 0.063 13.3 6.0 0.13 12.3 6.0 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Collagen PF01391.18 EKX38730.1 - 8.9e-13 47.8 55.3 2.6e-08 33.5 27.1 2.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Adaptin_binding PF10199.9 EKX38730.1 - 0.0012 19.5 1.4 0.0052 17.4 1.4 1.9 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 AF-4 PF05110.13 EKX38730.1 - 0.003 15.7 13.1 0.0039 15.4 13.1 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein BLOC1_2 PF10046.9 EKX38730.1 - 0.024 14.9 0.5 0.024 14.9 0.5 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SKA1 PF07160.12 EKX38730.1 - 0.31 10.9 8.2 0.27 11.0 0.3 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 HemX PF04375.14 EKX38730.1 - 1.5 8.0 8.5 0.72 9.1 1.2 2.1 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase FAM76 PF16046.5 EKX38730.1 - 3 7.1 11.0 6.1 6.1 11.0 1.5 1 1 0 1 1 1 0 FAM76 protein DUF2203 PF09969.9 EKX38730.1 - 3.7 8.3 8.9 10 6.8 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) TMF_TATA_bd PF12325.8 EKX38730.1 - 6.1 7.1 15.0 0.081 13.1 5.9 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding PIEZO PF15917.5 EKX38730.1 - 6.4 6.2 7.5 1.8 8.0 1.5 2.0 1 1 1 2 2 2 0 Piezo DUF3450 PF11932.8 EKX38730.1 - 7.2 5.8 12.3 0.24 10.7 3.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) ANAPC15 PF15243.6 EKX38730.1 - 8.9 6.8 17.1 8.1 6.9 6.9 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 TPR_6 PF13174.6 EKX38731.1 - 6.2 7.7 6.2 1.3e+02 3.5 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat GAT PF03127.14 EKX38737.1 - 6.2e-05 23.2 1.6 0.0001 22.5 1.6 1.3 1 0 0 1 1 1 1 GAT domain Mpp10 PF04006.12 EKX38738.1 - 0.42 9.0 25.7 0.45 8.9 25.7 1.0 1 0 0 1 1 1 0 Mpp10 protein DNA_pol_phi PF04931.13 EKX38738.1 - 0.83 7.7 31.4 0.79 7.8 31.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF5523 PF17661.1 EKX38738.1 - 1.3 8.7 18.1 1.4 8.6 18.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) NPR3 PF03666.13 EKX38738.1 - 2.2 7.0 12.0 2.3 6.9 12.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pox_Ag35 PF03286.14 EKX38738.1 - 2.4 7.9 20.4 3.3 7.4 20.4 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SpoIIP PF07454.11 EKX38738.1 - 2.7 7.4 10.7 2.6 7.4 10.7 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Nop14 PF04147.12 EKX38738.1 - 3.1 5.9 31.3 3.6 5.7 31.3 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 EKX38738.1 - 3.9 6.7 29.7 3.7 6.8 29.7 1.1 1 0 0 1 1 1 0 BUD22 CNDH2_C PF16858.5 EKX38738.1 - 4.1 7.2 14.7 4.5 7.1 14.7 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Vfa1 PF08432.10 EKX38738.1 - 6.6 7.0 17.4 9.2 6.5 17.4 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Dynactin_p62 PF05502.13 EKX38738.1 - 7.1 5.3 7.3 7 5.3 7.3 1.1 1 0 0 1 1 1 0 Dynactin p62 family Presenilin PF01080.17 EKX38738.1 - 8.8 5.0 9.9 8.2 5.1 9.9 1.0 1 0 0 1 1 1 0 Presenilin ELYS PF13934.6 EKX38739.1 - 0.028 14.4 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore complex assembly DUF2947 PF11163.8 EKX38740.1 - 0.03 14.2 0.4 0.033 14.0 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) DUF4468 PF14730.6 EKX38740.1 - 0.071 13.4 2.1 1.1 9.5 0.2 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4468) with TBP-like fold FAM76 PF16046.5 EKX38740.1 - 0.48 9.7 14.4 0.52 9.6 14.4 1.0 1 0 0 1 1 1 0 FAM76 protein DUF1840 PF08895.11 EKX38742.1 - 0.099 13.0 0.0 0.12 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Srg PF02118.21 EKX38744.1 - 0.045 13.4 0.0 0.066 12.9 0.0 1.1 1 0 0 1 1 1 0 Srg family chemoreceptor CcmH PF03918.14 EKX38744.1 - 0.14 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein TTL PF03133.15 EKX38745.1 - 6.8e-61 206.0 0.2 2.1e-46 158.4 0.3 3.6 2 1 1 3 3 3 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EKX38745.1 - 4.3e-06 26.2 0.3 0.00023 20.5 0.0 2.7 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EKX38745.1 - 0.0038 16.5 0.0 0.038 13.3 0.0 2.0 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp CDC45 PF02724.14 EKX38745.1 - 2.3 6.4 5.7 3.5 5.8 5.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Fibrillarin PF01269.17 EKX38747.1 - 0.089 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin DnaT PF17948.1 EKX38748.1 - 0.068 12.9 0.6 0.14 11.9 0.6 1.5 1 0 0 1 1 1 0 DnaT DNA-binding domain PsbP PF01789.16 EKX38750.1 - 2.1e-06 28.0 0.1 4.1e-06 27.0 0.1 1.6 1 1 0 1 1 1 1 PsbP DUF5082 PF16888.5 EKX38751.1 - 0.0032 17.8 0.1 0.0086 16.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) HIP1_clath_bdg PF16515.5 EKX38751.1 - 0.035 14.7 3.1 0.035 14.7 3.1 2.4 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 AATF-Che1 PF13339.6 EKX38751.1 - 0.2 12.3 4.9 0.076 13.7 1.4 1.9 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF5424 PF17462.2 EKX38752.1 - 0.074 13.0 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5424) End_beta_barrel PF12195.8 EKX38754.1 - 0.69 9.9 13.2 0.73 9.8 0.7 4.4 1 1 5 6 6 6 0 Beta barrel domain of bacteriophage endosialidase 5TM-5TMR_LYT PF07694.12 EKX38754.1 - 5 6.6 5.6 5.6 6.4 5.6 1.2 1 0 0 1 1 1 0 5TMR of 5TMR-LYT HSCB_C PF07743.13 EKX38755.1 - 0.026 15.0 0.8 0.026 15.0 0.8 3.3 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain Rab5-bind PF09311.11 EKX38755.1 - 0.038 13.4 13.3 0.022 14.2 8.4 2.0 2 0 0 2 2 2 0 Rabaptin-like protein AvrM-A PF18241.1 EKX38755.1 - 0.088 13.2 1.0 0.088 13.2 1.0 2.5 2 1 1 3 3 3 0 Flax-rust effector AvrM-A DUF948 PF06103.11 EKX38755.1 - 0.13 12.5 5.1 1.4 9.3 2.1 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Phage_Mu_Gam PF07352.12 EKX38755.1 - 0.13 12.1 6.8 3.1 7.7 1.7 2.9 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein CENP-F_leu_zip PF10473.9 EKX38755.1 - 0.15 12.1 25.0 0.073 13.1 8.7 3.1 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 EKX38755.1 - 0.16 10.8 18.2 0.12 11.2 6.6 2.9 2 1 1 3 3 3 0 Spc7 kinetochore protein Dynactin_p22 PF07426.11 EKX38755.1 - 0.22 11.4 15.0 0.18 11.7 9.1 2.1 2 0 0 2 2 2 0 Dynactin subunit p22 TerB_C PF15615.6 EKX38755.1 - 0.32 11.3 9.6 0.11 12.8 2.9 2.2 2 0 0 2 2 2 0 TerB-C domain Lebercilin PF15619.6 EKX38755.1 - 0.67 9.6 25.0 0.036 13.7 15.0 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease APG6_N PF17675.1 EKX38755.1 - 0.87 10.1 17.4 0.45 11.0 2.9 2.3 1 1 0 2 2 2 0 Apg6 coiled-coil region DUF745 PF05335.13 EKX38755.1 - 0.99 9.1 13.1 1.1 9.0 7.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Tropomyosin_1 PF12718.7 EKX38755.1 - 1.3 9.2 20.6 0.37 10.9 11.9 2.9 2 1 0 2 2 2 0 Tropomyosin like Golgin_A5 PF09787.9 EKX38755.1 - 1.4 8.3 16.9 2.5 7.5 11.1 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 Syntaxin-6_N PF09177.11 EKX38755.1 - 1.6 9.4 13.3 3.5 8.2 3.1 2.9 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Fez1 PF06818.15 EKX38755.1 - 1.6 9.2 20.2 2.8 8.4 20.2 1.5 1 1 0 1 1 1 0 Fez1 DLP_helical PF18709.1 EKX38755.1 - 2 7.5 13.0 3.4 6.8 0.8 3.0 2 1 1 3 3 3 0 Dynamin-like helical domain DHR10 PF18595.1 EKX38755.1 - 2.9 8.0 25.5 0.81 9.8 7.0 3.1 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain FliD_N PF02465.18 EKX38755.1 - 3.2 8.5 10.9 0.68 10.7 1.2 2.9 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Seryl_tRNA_N PF02403.22 EKX38755.1 - 3.5 7.9 14.8 5.9 7.2 4.2 3.2 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Matrilin_ccoil PF10393.9 EKX38755.1 - 3.5 7.6 8.0 20 5.1 0.5 3.7 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin EzrA PF06160.12 EKX38755.1 - 3.9 5.5 15.5 1 7.5 8.6 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Nup54 PF13874.6 EKX38755.1 - 5.7 7.1 19.1 10 6.3 10.5 2.5 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 DUF1664 PF07889.12 EKX38755.1 - 6.3 6.9 14.8 1.4 9.0 2.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) HemX PF04375.14 EKX38755.1 - 7 5.8 15.6 5.6 6.2 3.8 2.9 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase ABC_tran_CTD PF16326.5 EKX38755.1 - 8.9 6.7 15.1 7.3 6.9 4.6 3.6 2 1 1 3 3 3 0 ABC transporter C-terminal domain SAP PF02037.27 EKX38756.1 - 6.3e-11 41.8 0.5 1.2e-10 40.9 0.5 1.4 1 0 0 1 1 1 1 SAP domain Telomere_Sde2_2 PF13297.6 EKX38756.1 - 0.097 12.3 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Telomere stability C-terminal PAPS_reduct PF01507.19 EKX38757.1 - 3.2e-21 76.1 0.0 1.8e-20 73.7 0.0 2.2 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family MoCF_biosynth PF00994.24 EKX38757.1 - 2.2e-18 66.3 0.0 4.2e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain SLY PF12485.8 EKX38757.1 - 7.3 7.3 7.9 1.1 10.0 0.4 2.8 3 0 0 3 3 3 0 Lymphocyte signaling adaptor protein DCB PF16213.5 EKX38758.1 - 3.5e-12 46.4 0.1 9.9e-12 44.9 0.1 1.7 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 EKX38758.1 - 6.8e-08 32.6 4.5 9.5e-08 32.1 3.4 1.8 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal SelK_SelG PF10961.8 EKX38758.1 - 0.17 12.6 3.6 0.47 11.1 3.6 1.7 1 0 0 1 1 1 0 Selenoprotein SelK_SelG FlgN PF05130.12 EKX38758.1 - 3.4 8.2 10.5 0.34 11.4 1.1 2.4 2 0 0 2 2 2 0 FlgN protein DUF1981 PF09324.10 EKX38759.1 - 2.3e-09 37.0 0.0 7.1e-09 35.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1981) MSA-2c PF12238.8 EKX38759.1 - 9.4 6.2 5.6 11 6.0 0.2 2.3 2 0 0 2 2 2 0 Merozoite surface antigen 2c EF-hand_1 PF00036.32 EKX38760.1 - 7.7e-18 62.7 3.3 7.1e-06 25.2 0.2 4.0 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EKX38760.1 - 2.6e-16 58.1 1.1 1.9e-05 24.2 0.0 4.5 4 1 1 5 5 5 3 EF-hand domain EF-hand_7 PF13499.6 EKX38760.1 - 9.5e-15 54.8 2.0 3.8e-11 43.3 0.1 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX38760.1 - 1.8e-13 49.3 4.0 0.0005 19.4 0.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EKX38760.1 - 2.1e-11 43.5 6.2 1.3e-05 24.9 0.6 3.5 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 EKX38760.1 - 0.0017 18.6 0.0 0.0036 17.6 0.0 1.5 2 0 0 2 2 2 1 EF-hand domain Caleosin PF05042.13 EKX38760.1 - 0.0033 17.4 0.0 1.1 9.2 0.0 2.2 1 1 1 2 2 2 2 Caleosin related protein Csm1_N PF18504.1 EKX38761.1 - 0.038 14.3 1.1 0.038 14.3 1.1 7.0 5 2 4 9 9 9 0 Csm1 N-terminal domain DUF218 PF02698.17 EKX38762.1 - 1.2e-05 25.3 0.0 0.073 13.1 0.0 2.3 2 0 0 2 2 2 2 DUF218 domain BT1 PF03092.16 EKX38763.1 - 7.1e-71 239.0 34.2 2.1e-34 118.6 19.0 4.1 2 1 0 2 2 2 2 BT1 family CUB PF00431.20 EKX38764.1 - 7.4e-06 26.3 0.0 5e-05 23.6 0.0 2.6 1 0 0 1 1 1 1 CUB domain Pilin PF00114.19 EKX38764.1 - 0.047 14.6 0.0 0.42 11.6 0.0 2.7 1 0 0 1 1 1 0 Pilin (bacterial filament) CS PF04969.16 EKX38768.1 - 1.8e-11 44.9 0.1 1.5e-10 42.0 0.1 2.3 1 1 0 1 1 1 1 CS domain SAM_1 PF00536.30 EKX38768.1 - 2.8e-06 27.7 0.2 1.2e-05 25.6 0.1 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EKX38768.1 - 4.6e-06 26.6 0.1 1.6e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) COX5A PF02284.16 EKX38768.1 - 0.12 12.3 0.1 0.35 10.9 0.0 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va DSPc PF00782.20 EKX38769.1 - 3.5e-23 81.9 0.0 6.6e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CPBP PF02517.16 EKX38769.1 - 1.7e-11 44.3 7.1 1.7e-11 44.3 7.1 2.4 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease Init_tRNA_PT PF04179.12 EKX38769.1 - 0.012 15.9 0.0 0.028 14.7 0.0 1.6 1 0 0 1 1 1 0 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 EKX38769.1 - 0.034 14.3 0.0 0.062 13.4 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 EKX38769.1 - 0.039 13.5 0.1 0.066 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 EKX38769.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family RIH_assoc PF08454.11 EKX38770.1 - 9.4e-22 76.8 0.4 8.5e-20 70.5 0.4 3.4 2 0 0 2 2 2 1 RyR and IP3R Homology associated Ins145_P3_rec PF08709.11 EKX38770.1 - 3.2e-19 69.0 0.1 1.3e-18 67.0 0.1 2.1 2 0 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RYDR_ITPR PF01365.21 EKX38770.1 - 1.4e-18 67.1 6.8 9.3e-12 44.8 0.2 3.3 2 0 0 2 2 2 2 RIH domain Ion_trans PF00520.31 EKX38770.1 - 1.3e-12 47.5 7.8 4.3e-12 45.8 7.8 1.9 1 0 0 1 1 1 1 Ion transport protein MIR PF02815.19 EKX38770.1 - 9.6e-07 28.8 0.3 0.011 15.6 0.0 4.0 3 1 0 3 3 3 2 MIR domain GPI2 PF06432.11 EKX38770.1 - 0.087 12.3 0.7 0.19 11.2 0.7 1.5 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase Methyltransf_16 PF10294.9 EKX38771.1 - 3.7e-12 46.3 0.4 4.4e-07 29.8 0.0 2.8 2 1 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 EKX38771.1 - 1.3e-07 31.6 0.0 1.9e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX38771.1 - 0.0052 16.6 0.0 2.8 7.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 EKX38771.1 - 0.013 15.1 0.0 0.031 13.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_12 PF08242.12 EKX38771.1 - 0.019 15.7 0.2 0.35 11.6 0.2 2.2 1 1 0 1 1 1 0 Methyltransferase domain MSL2-CXC PF16682.5 EKX38771.1 - 0.067 13.3 1.2 0.11 12.6 1.2 1.3 1 0 0 1 1 1 0 CXC domain of E3 ubiquitin-protein ligase MSL2 DREV PF05219.12 EKX38771.1 - 0.07 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_25 PF13649.6 EKX38771.1 - 0.088 13.5 0.1 2.9 8.7 0.1 2.3 2 0 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.20 EKX38771.1 - 0.092 11.8 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Pox_vIL-18BP PF05566.12 EKX38771.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Orthopoxvirus interleukin 18 binding protein Basic PF01586.16 EKX38771.1 - 0.27 12.5 1.5 12 7.1 0.3 2.5 2 0 0 2 2 2 0 Myogenic Basic domain IGPS PF00218.21 EKX38772.1 - 0.0038 16.4 0.9 0.007 15.6 0.9 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase AlaDh_PNT_C PF01262.21 EKX38772.1 - 0.077 12.3 0.4 0.13 11.6 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ATX_III PF08098.11 EKX38773.1 - 0.43 10.6 4.2 7.5 6.7 1.7 2.6 2 0 0 2 2 2 0 Anemonia sulcata toxin III family PX PF00787.24 EKX38774.1 - 0.078 13.0 0.7 0.24 11.4 0.2 2.1 2 0 0 2 2 2 0 PX domain Phlebovirus_NSM PF07246.11 EKX38774.1 - 2 7.7 10.0 0.66 9.3 1.3 2.7 3 0 0 3 3 3 0 Phlebovirus nonstructural protein NS-M FliJ PF02050.16 EKX38774.1 - 5.5 7.2 11.3 1.3 9.2 3.3 3.0 3 0 0 3 3 3 0 Flagellar FliJ protein DUF3496 PF12001.8 EKX38774.1 - 5.5 7.4 11.0 5.9 7.3 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3496) CENP-H PF05837.12 EKX38774.1 - 7.6 7.0 15.2 2.6 8.5 0.2 3.6 3 0 0 3 3 3 0 Centromere protein H (CENP-H) FAM176 PF14851.6 EKX38775.1 - 0.0009 18.9 3.3 0.0011 18.6 3.3 1.2 1 0 0 1 1 1 1 FAM176 family Pox_Ag35 PF03286.14 EKX38775.1 - 0.0045 16.8 7.4 0.0051 16.6 7.4 1.1 1 0 0 1 1 1 1 Pox virus Ag35 surface protein CENP-B_dimeris PF09026.10 EKX38775.1 - 0.0083 16.5 18.8 0.011 16.1 18.8 1.2 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Sigma70_ner PF04546.13 EKX38775.1 - 0.023 14.6 8.2 0.024 14.5 8.2 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Afi1 PF07792.12 EKX38775.1 - 0.027 14.9 4.0 0.031 14.8 4.0 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF4820 PF16091.5 EKX38775.1 - 0.053 12.9 1.2 0.054 12.8 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) SDA1 PF05285.12 EKX38775.1 - 0.057 12.8 10.2 0.061 12.8 10.2 1.0 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 EKX38775.1 - 0.059 11.9 7.7 0.058 11.9 7.7 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 EKX38775.1 - 0.061 12.7 8.4 0.062 12.6 8.4 1.0 1 0 0 1 1 1 0 BUD22 RXT2_N PF08595.11 EKX38775.1 - 0.062 13.3 8.1 0.075 13.1 8.1 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF5431 PF17496.2 EKX38775.1 - 0.073 13.2 0.0 0.14 12.3 0.0 1.5 2 0 0 2 2 1 0 Family of unknown function (DUF5431) GCIP PF13324.6 EKX38775.1 - 0.087 12.4 9.3 0.099 12.2 9.3 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF913 PF06025.12 EKX38775.1 - 0.11 11.5 0.2 0.11 11.5 0.2 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Vfa1 PF08432.10 EKX38775.1 - 0.12 12.7 3.5 0.15 12.4 3.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Slu7 PF11708.8 EKX38775.1 - 0.16 11.7 8.1 0.19 11.5 8.1 1.0 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Nop53 PF07767.11 EKX38775.1 - 0.17 11.2 9.6 0.19 11.1 9.6 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) FYDLN_acid PF09538.10 EKX38775.1 - 0.22 12.2 13.5 0.27 11.9 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) RPN2_C PF18004.1 EKX38775.1 - 0.23 11.4 4.1 0.27 11.1 4.1 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain NOA36 PF06524.12 EKX38775.1 - 0.23 10.7 18.2 0.29 10.4 18.2 1.1 1 0 0 1 1 1 0 NOA36 protein SGT1 PF07093.11 EKX38775.1 - 0.23 9.8 4.4 0.22 9.9 4.4 1.0 1 0 0 1 1 1 0 SGT1 protein DUF2457 PF10446.9 EKX38775.1 - 0.23 10.5 21.2 0.27 10.3 21.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF2722 PF10846.8 EKX38775.1 - 0.24 10.3 3.5 0.24 10.3 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DNA_pol_phi PF04931.13 EKX38775.1 - 0.28 9.3 19.7 0.3 9.1 19.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 EKX38775.1 - 0.32 10.2 5.1 0.32 10.2 5.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.12 EKX38775.1 - 0.44 8.7 14.2 0.47 8.6 14.2 1.0 1 0 0 1 1 1 0 Nop14-like family TFB6 PF17110.5 EKX38775.1 - 0.8 9.4 5.8 0.95 9.2 5.8 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Sporozoite_P67 PF05642.11 EKX38775.1 - 1 7.4 6.9 1 7.4 6.9 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4746 PF15928.5 EKX38775.1 - 1.1 8.6 5.8 1.3 8.4 5.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PBP1_TM PF14812.6 EKX38775.1 - 1.3 9.4 15.3 1.7 9.1 15.3 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 EKX38775.1 - 1.5 8.5 18.5 1.8 8.2 18.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Utp14 PF04615.13 EKX38775.1 - 1.7 7.1 14.7 2.1 6.8 14.7 1.0 1 0 0 1 1 1 0 Utp14 protein Nucleo_P87 PF07267.11 EKX38775.1 - 2.1 7.1 8.1 2.3 7.0 8.1 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.14 EKX38775.1 - 2.2 6.5 15.8 2.6 6.2 15.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Roughex PF06020.11 EKX38775.1 - 2.3 7.2 9.4 2.6 7.1 9.4 1.0 1 0 0 1 1 1 0 Drosophila roughex protein Astro_capsid_p PF12226.8 EKX38775.1 - 2.5 7.2 12.9 2.8 7.0 12.9 1.0 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF4637 PF15470.6 EKX38775.1 - 2.7 7.7 13.0 3.5 7.3 13.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Rhabdo_ncap PF00945.18 EKX38775.1 - 3.4 6.4 5.5 3.7 6.3 5.5 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein GOLD_2 PF13897.6 EKX38775.1 - 5.9 7.4 6.2 7.7 7.0 6.2 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking PI3K_1B_p101 PF10486.9 EKX38775.1 - 8.7 4.0 6.9 9.9 3.8 6.9 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit ABC2_membrane PF01061.24 EKX38776.1 - 2.2e-29 102.4 29.1 3.1e-29 101.9 29.1 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EKX38776.1 - 1.6e-24 87.0 0.0 2.3e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EKX38776.1 - 4.1e-09 36.7 0.0 0.00043 20.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EKX38776.1 - 0.00016 21.2 0.0 0.00042 19.8 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EKX38776.1 - 0.00061 19.5 2.0 0.00069 19.3 0.2 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EKX38776.1 - 0.00099 19.7 0.0 0.0017 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EKX38776.1 - 0.0019 18.6 0.0 0.0035 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EKX38776.1 - 0.014 15.7 0.2 0.032 14.5 0.2 1.8 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EKX38776.1 - 0.019 14.8 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase ABC_ATPase PF09818.9 EKX38776.1 - 0.026 13.3 0.0 0.048 12.5 0.0 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class T2SSE PF00437.20 EKX38776.1 - 0.044 12.8 0.1 0.071 12.1 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 EKX38776.1 - 0.045 13.3 0.1 0.09 12.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EKX38776.1 - 0.066 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain IstB_IS21 PF01695.17 EKX38776.1 - 0.19 11.5 0.0 0.39 10.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Kinocilin PF15033.6 EKX38776.1 - 0.5 10.0 5.3 0.18 11.5 1.9 1.9 2 0 0 2 2 2 0 Kinocilin protein ABC2_membrane PF01061.24 EKX38777.1 - 2.2e-29 102.4 29.1 3.2e-29 101.9 29.1 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EKX38777.1 - 1.6e-24 87.0 0.0 2.3e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EKX38777.1 - 4.1e-09 36.7 0.0 0.00043 20.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EKX38777.1 - 0.00016 21.2 0.0 0.00042 19.8 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EKX38777.1 - 0.00062 19.5 2.0 0.00069 19.3 0.2 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EKX38777.1 - 0.00099 19.7 0.0 0.0017 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EKX38777.1 - 0.0019 18.6 0.0 0.0036 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EKX38777.1 - 0.014 15.7 0.2 0.033 14.5 0.2 1.8 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EKX38777.1 - 0.02 14.8 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase ABC_ATPase PF09818.9 EKX38777.1 - 0.026 13.3 0.0 0.048 12.5 0.0 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class T2SSE PF00437.20 EKX38777.1 - 0.043 12.9 0.1 0.07 12.2 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 EKX38777.1 - 0.046 13.3 0.1 0.091 12.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EKX38777.1 - 0.066 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain IstB_IS21 PF01695.17 EKX38777.1 - 0.19 11.5 0.0 0.39 10.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Kinocilin PF15033.6 EKX38777.1 - 0.68 9.6 5.6 0.18 11.4 1.9 1.9 2 0 0 2 2 2 0 Kinocilin protein FAM176 PF14851.6 EKX38778.1 - 0.0008 19.1 3.4 0.001 18.8 3.4 1.2 1 0 0 1 1 1 1 FAM176 family CENP-B_dimeris PF09026.10 EKX38778.1 - 0.0082 16.5 18.8 0.011 16.1 18.8 1.2 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Pox_Ag35 PF03286.14 EKX38778.1 - 0.0087 15.9 8.5 0.0097 15.7 8.5 1.1 1 0 0 1 1 1 1 Pox virus Ag35 surface protein BUD22 PF09073.10 EKX38778.1 - 0.022 14.1 7.3 0.022 14.1 7.3 1.0 1 0 0 1 1 1 0 BUD22 Afi1 PF07792.12 EKX38778.1 - 0.023 15.2 3.8 0.026 15.0 3.8 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Sigma70_ner PF04546.13 EKX38778.1 - 0.027 14.4 8.4 0.028 14.3 8.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF5431 PF17496.2 EKX38778.1 - 0.027 14.6 0.0 0.052 13.7 0.0 1.5 2 0 0 2 2 1 0 Family of unknown function (DUF5431) GCIP PF13324.6 EKX38778.1 - 0.037 13.6 8.1 0.041 13.5 8.1 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting RXT2_N PF08595.11 EKX38778.1 - 0.042 13.9 7.8 0.051 13.6 7.8 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4820 PF16091.5 EKX38778.1 - 0.046 13.1 1.5 0.046 13.1 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RRN3 PF05327.11 EKX38778.1 - 0.072 11.6 8.2 0.07 11.7 8.2 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop53 PF07767.11 EKX38778.1 - 0.075 12.4 8.7 0.083 12.3 8.7 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Vfa1 PF08432.10 EKX38778.1 - 0.08 13.3 3.1 0.094 13.0 3.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF913 PF06025.12 EKX38778.1 - 0.091 11.7 0.3 0.093 11.7 0.3 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SDA1 PF05285.12 EKX38778.1 - 0.094 12.1 11.1 0.1 12.0 11.1 1.0 1 0 0 1 1 1 0 SDA1 Slu7 PF11708.8 EKX38778.1 - 0.1 12.3 7.6 0.12 12.1 7.6 1.0 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor TFB6 PF17110.5 EKX38778.1 - 0.12 12.1 3.2 0.12 12.1 3.2 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH RPN2_C PF18004.1 EKX38778.1 - 0.12 12.2 3.5 0.14 12.0 3.5 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain FYDLN_acid PF09538.10 EKX38778.1 - 0.13 12.9 13.1 0.16 12.7 13.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) NOA36 PF06524.12 EKX38778.1 - 0.14 11.4 17.5 0.17 11.1 17.5 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 EKX38778.1 - 0.16 10.0 19.0 0.18 9.9 19.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF2722 PF10846.8 EKX38778.1 - 0.18 10.8 3.5 0.17 10.8 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SGT1 PF07093.11 EKX38778.1 - 0.18 10.2 4.2 0.17 10.3 4.2 1.0 1 0 0 1 1 1 0 SGT1 protein DUF2457 PF10446.9 EKX38778.1 - 0.23 10.6 21.2 0.27 10.3 21.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 EKX38778.1 - 0.29 9.3 13.7 0.31 9.2 13.7 1.0 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.16 EKX38778.1 - 0.38 9.9 5.5 0.39 9.9 5.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sporozoite_P67 PF05642.11 EKX38778.1 - 0.4 8.7 5.7 0.38 8.8 5.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nucleo_P87 PF07267.11 EKX38778.1 - 0.86 8.4 7.0 0.93 8.3 7.0 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Cwf_Cwc_15 PF04889.12 EKX38778.1 - 0.98 9.1 17.9 1.2 8.8 17.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.6 EKX38778.1 - 1.2 9.5 15.3 1.7 9.1 15.3 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4746 PF15928.5 EKX38778.1 - 1.7 8.0 6.5 1.8 7.9 6.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Utp14 PF04615.13 EKX38778.1 - 1.7 7.1 14.7 2.1 6.8 14.7 1.0 1 0 0 1 1 1 0 Utp14 protein CDC45 PF02724.14 EKX38778.1 - 1.8 6.8 15.5 2.1 6.5 15.5 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4637 PF15470.6 EKX38778.1 - 2.5 7.8 12.9 3.1 7.5 12.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Roughex PF06020.11 EKX38778.1 - 3.9 6.5 10.1 4.2 6.4 10.1 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Rhabdo_ncap PF00945.18 EKX38778.1 - 6 5.6 6.2 6.6 5.5 6.2 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein GOLD_2 PF13897.6 EKX38778.1 - 6 7.4 6.2 7.7 7.0 6.2 1.2 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking PI3K_1B_p101 PF10486.9 EKX38778.1 - 8 4.1 6.7 8.4 4.0 6.7 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Astro_capsid_p PF12226.8 EKX38778.1 - 9.4 5.3 14.7 11 5.1 14.7 1.0 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Bromodomain PF00439.25 EKX38779.1 - 5.3e-09 36.0 0.0 1.2e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_10 PF13673.7 EKX38779.1 - 2.4e-05 24.2 0.0 5.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EKX38779.1 - 0.0029 18.0 0.0 0.0069 16.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain LysM PF01476.20 EKX38779.1 - 0.0039 17.2 0.0 2.7 8.1 0.0 3.3 3 0 0 3 3 3 1 LysM domain Acetyltransf_1 PF00583.25 EKX38779.1 - 0.023 14.9 0.0 0.057 13.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family His_Phos_1 PF00300.22 EKX38780.1 - 1.2e-12 47.9 0.0 1.9e-12 47.3 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Sep15_SelM PF08806.11 EKX38781.1 - 4.7e-18 65.1 0.0 7.1e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Sep15/SelM redox domain Guanylate_cyc PF00211.20 EKX38782.1 - 1.2e-25 90.2 0.1 8.2e-13 48.4 0.0 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 EKX38782.1 - 1.8e-14 54.5 0.0 5.9e-14 52.8 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain TPR_12 PF13424.6 EKX38782.1 - 2.3e-05 24.6 3.0 0.14 12.5 0.9 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat RuvB_N PF05496.12 EKX38782.1 - 0.038 13.8 0.0 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EKX38782.1 - 0.043 14.1 0.0 1.3 9.2 0.0 3.2 2 1 0 2 2 2 0 AAA domain ANAPC3 PF12895.7 EKX38782.1 - 0.047 13.9 0.8 3.6 7.9 0.1 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EKX38782.1 - 0.064 13.4 7.1 2.1 8.7 0.0 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 EKX38782.1 - 0.084 12.7 1.1 18 5.4 0.0 4.3 6 0 0 6 6 6 0 Tetratricopeptide repeat NB-ARC PF00931.22 EKX38782.1 - 0.095 11.9 0.2 1.8 7.7 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain TPR_8 PF13181.6 EKX38782.1 - 0.13 12.5 0.1 1.1 9.7 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Big_1 PF02369.16 EKX38783.1 - 0.024 14.6 3.6 6 7.0 0.0 4.7 6 0 0 6 6 6 0 Bacterial Ig-like domain (group 1) NOG1 PF06858.14 EKX38783.1 - 0.025 14.3 0.2 0.062 13.1 0.2 1.6 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) CarboxypepD_reg PF13620.6 EKX38783.1 - 0.026 14.8 1.2 17 5.8 0.0 4.4 4 1 0 4 4 4 0 Carboxypeptidase regulatory-like domain eIF2_C PF09173.11 EKX38783.1 - 0.18 12.1 0.0 1 9.6 0.0 2.2 2 0 0 2 2 2 0 Initiation factor eIF2 gamma, C terminal PKD_channel PF08016.12 EKX38786.1 - 5.1e-36 124.3 7.6 5.1e-36 124.3 7.6 1.4 2 0 0 2 2 2 1 Polycystin cation channel Glutaredoxin PF00462.24 EKX38786.1 - 0.37 11.0 1.0 1.2 9.4 0.6 2.1 1 1 0 1 1 1 0 Glutaredoxin BIR PF00653.21 EKX38787.1 - 3.6e-19 69.2 0.5 6.5e-19 68.4 0.5 1.4 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain PDZ PF00595.24 EKX38787.1 - 1.9e-17 63.4 0.7 2.1e-08 34.4 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX38787.1 - 3.7e-10 40.0 1.1 0.00037 20.7 0.1 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EKX38787.1 - 4.5e-10 39.2 2.7 5.1e-07 29.4 0.3 2.7 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 EKX38787.1 - 0.0014 18.6 1.3 0.75 9.8 0.2 3.5 2 2 0 2 2 2 2 Tricorn protease PDZ domain PRK PF00485.18 EKX38788.1 - 3.8e-08 33.3 0.0 7.5e-08 32.3 0.0 1.5 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EKX38788.1 - 8.5e-08 32.8 0.0 1.7e-07 31.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EKX38788.1 - 0.0012 19.3 0.0 0.0016 19.0 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EKX38788.1 - 0.0013 19.2 0.0 0.0016 18.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EKX38788.1 - 0.0014 18.8 0.1 0.21 11.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 EKX38788.1 - 0.0014 18.1 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ATP_bind_1 PF03029.17 EKX38788.1 - 0.0032 17.3 0.0 0.0048 16.7 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 EKX38788.1 - 0.0045 17.1 0.0 0.0084 16.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 EKX38788.1 - 0.0047 17.2 0.3 0.012 15.9 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EKX38788.1 - 0.0057 16.9 0.0 0.015 15.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EKX38788.1 - 0.0068 15.7 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin MeaB PF03308.16 EKX38788.1 - 0.0089 15.0 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Cytidylate_kin PF02224.18 EKX38788.1 - 0.012 15.3 0.1 0.025 14.3 0.1 1.5 1 0 0 1 1 1 0 Cytidylate kinase CPT PF07931.12 EKX38788.1 - 0.012 15.4 0.3 0.048 13.5 0.3 1.8 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.6 EKX38788.1 - 0.027 14.9 0.2 2.3 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 EKX38788.1 - 0.029 14.3 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 CoaE PF01121.20 EKX38788.1 - 0.036 13.8 0.1 6.9 6.3 0.0 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase IstB_IS21 PF01695.17 EKX38788.1 - 0.045 13.5 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA12 PF10443.9 EKX38788.1 - 0.061 12.0 0.0 0.078 11.7 0.0 1.1 1 0 0 1 1 1 0 RNA12 protein AAA_5 PF07728.14 EKX38788.1 - 0.062 13.3 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 EKX38788.1 - 0.1 13.1 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 EKX38788.1 - 0.1 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 EKX38788.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 NTPase APS_kinase PF01583.20 EKX38788.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.6 2 0 0 2 2 2 0 Adenylylsulphate kinase ADK PF00406.22 EKX38788.1 - 0.14 12.2 0.1 2.3 8.3 0.0 2.1 2 0 0 2 2 2 0 Adenylate kinase RNA_helicase PF00910.22 EKX38788.1 - 0.15 12.5 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 EKX38788.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EKX38788.1 - 0.19 11.2 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Lin0512_fam PF09585.10 EKX38789.1 - 1.1e-34 118.9 0.0 1.2e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical protein (Lin0512_fam) ODR4-like PF14778.6 EKX38790.1 - 4e-05 22.8 0.0 4.8e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Olfactory receptor 4-like Toxin_38 PF14866.6 EKX38791.1 - 0.045 14.0 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Potassium channel toxin FluMu_N PF17891.1 EKX38791.1 - 0.099 12.4 0.0 0.37 10.6 0.0 2.0 1 0 0 1 1 1 0 Mu-like prophage FluMu N-terminal domain RhoGEF PF00621.20 EKX38792.1 - 6.4e-19 68.9 0.9 6.4e-19 68.9 0.9 2.2 3 0 0 3 3 3 1 RhoGEF domain EF-hand_1 PF00036.32 EKX38792.1 - 3.4e-18 63.8 0.6 7.8e-08 31.3 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX38792.1 - 4e-14 52.8 0.3 1.9e-13 50.6 0.3 2.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX38792.1 - 4.1e-14 51.2 0.1 1.2e-05 24.8 0.0 3.3 3 0 0 3 3 2 2 EF-hand domain EF-hand_5 PF13202.6 EKX38792.1 - 5.9e-12 44.5 1.1 3.7e-07 29.3 0.2 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX38792.1 - 6.5e-08 32.3 0.2 0.00015 21.6 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair WW PF00397.26 EKX38792.1 - 3.7e-07 30.1 3.4 7.6e-07 29.1 3.4 1.5 1 0 0 1 1 1 1 WW domain MIT PF04212.18 EKX38792.1 - 0.00035 20.6 1.4 0.00092 19.2 1.4 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain EF-hand_4 PF12763.7 EKX38792.1 - 0.0013 18.6 0.7 0.045 13.7 0.2 2.8 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EKX38792.1 - 0.0014 18.9 0.3 0.004 17.5 0.3 1.9 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 EKX38792.1 - 0.0067 16.4 0.1 0.11 12.4 0.1 2.4 1 1 1 2 2 2 1 Caleosin related protein RST PF12174.8 EKX38792.1 - 0.012 15.5 0.0 0.1 12.6 0.0 2.4 2 1 1 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain FRB_dom PF08771.11 EKX38792.1 - 0.14 12.6 2.6 2 8.9 0.2 3.2 4 0 0 4 4 4 0 FKBP12-rapamycin binding domain PDZ_6 PF17820.1 EKX38793.1 - 0.063 13.1 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PDZ_2 PF13180.6 EKX38793.1 - 0.099 13.0 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 PDZ domain LRR_6 PF13516.6 EKX38794.1 - 4.6e-36 119.8 24.6 1.5e-06 27.8 0.5 8.2 8 0 0 8 8 8 8 Leucine Rich repeat LRR_4 PF12799.7 EKX38794.1 - 6.3e-14 51.9 14.7 0.00044 20.6 2.2 5.4 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX38794.1 - 2.4e-09 36.5 12.8 2.9 8.8 0.1 7.5 7 1 1 8 8 8 4 Leucine Rich Repeat LRR_8 PF13855.6 EKX38794.1 - 1.7e-07 30.9 22.6 0.16 11.7 0.0 6.5 2 1 4 6 6 6 6 Leucine rich repeat SPRY PF00622.28 EKX38795.1 - 3.7e-10 40.0 0.0 1.2e-05 25.4 0.0 2.3 2 0 0 2 2 2 2 SPRY domain LysM PF01476.20 EKX38796.1 - 4.5e-13 49.0 0.3 1.2e-05 25.3 0.0 2.3 2 0 0 2 2 2 2 LysM domain DUF222 PF02720.17 EKX38800.1 - 0.13 11.7 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF222) Fiji_64_capsid PF05880.11 EKX38800.1 - 0.14 10.7 0.0 0.17 10.4 0.0 1.0 1 0 0 1 1 1 0 Fijivirus 64 kDa capsid protein Iron_permease PF04120.12 EKX38800.1 - 0.3 10.9 0.6 0.41 10.4 0.0 1.5 2 0 0 2 2 2 0 Low affinity iron permease TEX33 PF15400.6 EKX38801.1 - 0.034 14.7 0.1 0.037 14.5 0.1 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 33 protein family CxC2 PF18803.1 EKX38801.1 - 0.038 14.2 0.0 0.049 13.8 0.0 1.1 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases His_Phos_1 PF00300.22 EKX38803.1 - 2.6e-14 53.4 0.3 1.8e-08 34.3 0.0 3.8 1 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 1) Laminin_G_3 PF13385.6 EKX38805.1 - 3.5e-14 53.2 5.8 6.2e-14 52.4 3.3 2.0 1 1 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Ephrin_rec_like PF07699.13 EKX38806.1 - 2.3e-39 132.9 108.1 3.7e-11 42.6 5.5 11.7 4 3 8 12 12 12 12 Putative ephrin-receptor like NCD3G PF07562.14 EKX38806.1 - 1.8e-05 24.6 80.3 0.019 14.9 2.0 9.2 4 3 2 9 9 9 8 Nine Cysteines Domain of family 3 GPCR zf-RRN7 PF11781.8 EKX38806.1 - 0.0006 19.4 33.1 0.13 12.0 3.9 5.3 3 1 1 4 4 4 4 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 TNFR_c6 PF00020.18 EKX38806.1 - 0.021 15.2 74.5 0.13 12.7 3.8 12.0 4 4 8 14 14 14 0 TNFR/NGFR cysteine-rich region VSP PF03302.13 EKX38806.1 - 0.022 13.6 100.6 0.019 13.9 3.7 5.3 1 1 4 5 5 5 0 Giardia variant-specific surface protein EGF_MSP1_1 PF12946.7 EKX38806.1 - 0.09 12.8 22.9 1.5 9.0 2.6 5.9 5 0 0 5 5 5 0 MSP1 EGF domain 1 NCD3G PF07562.14 EKX38807.1 - 7.9e-12 45.0 58.9 0.006 16.5 1.3 8.5 5 2 4 10 10 10 9 Nine Cysteines Domain of family 3 GPCR Ephrin_rec_like PF07699.13 EKX38807.1 - 3.1e-11 42.9 91.2 9e-05 22.2 6.9 9.5 2 2 7 10 10 10 9 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX38807.1 - 0.081 13.3 63.1 0.91 10.0 0.8 11.1 4 3 6 10 10 10 0 TNFR/NGFR cysteine-rich region VSP PF03302.13 EKX38807.1 - 0.44 9.4 75.4 0.7 8.7 32.9 3.4 1 1 2 3 3 3 0 Giardia variant-specific surface protein Atx10homo_assoc PF09759.9 EKX38808.1 - 0.014 15.4 0.7 12 6.0 0.0 3.6 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain PglD_N PF17836.1 EKX38808.1 - 0.086 13.5 0.4 0.3 11.8 0.2 1.9 2 0 0 2 2 2 0 PglD N-terminal domain PUL PF08324.11 EKX38808.1 - 0.089 12.0 0.1 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 PUL domain HAD_2 PF13419.6 EKX38809.1 - 9.6e-31 107.2 0.0 1.4e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EKX38809.1 - 9.7e-19 68.5 0.0 2.6e-17 63.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EKX38809.1 - 3.1e-06 27.7 0.0 4.5e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EKX38809.1 - 6.9e-06 26.0 0.1 2.7e-05 24.1 0.0 2.0 1 1 1 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EKX38809.1 - 0.0026 17.8 0.0 0.44 10.7 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Zn_clus PF00172.18 EKX38810.1 - 1.3e-05 25.3 11.8 1.6e-05 24.9 8.5 2.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain XG_FTase PF03254.13 EKX38811.1 - 5.2e-05 22.0 0.0 9.2e-05 21.2 0.0 1.3 1 0 0 1 1 1 1 Xyloglucan fucosyltransferase Trypan_PARP PF05887.11 EKX38811.1 - 0.22 11.5 28.8 0.36 10.8 28.8 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SARG PF15385.6 EKX38811.1 - 0.9 8.7 18.7 1.4 8.1 18.7 1.2 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein Arm PF00514.23 EKX38812.1 - 0 1855.8 236.8 5.7e-12 45.2 0.1 70.2 70 0 0 70 70 70 69 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EKX38812.1 - 2.9e-111 362.9 160.5 2.3e-06 28.0 0.1 50.2 42 14 11 53 53 52 26 HEAT-like repeat HEAT_2 PF13646.6 EKX38812.1 - 1.1e-92 304.5 122.0 4.1e-06 27.1 0.1 32.4 9 7 25 38 38 38 32 HEAT repeats Arm_2 PF04826.13 EKX38812.1 - 4.4e-88 295.0 119.1 3.5e-07 29.9 4.6 26.6 3 3 19 26 26 26 19 Armadillo-like KAP PF05804.12 EKX38812.1 - 4.3e-79 266.5 31.5 5.8e-11 41.3 0.0 16.1 4 3 10 16 16 16 12 Kinesin-associated protein (KAP) Cnd1 PF12717.7 EKX38812.1 - 2.3e-53 180.6 60.1 0.002 18.2 0.4 26.5 6 5 24 31 31 31 15 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EKX38812.1 - 3.6e-40 132.5 150.5 0.32 11.4 0.0 47.6 54 0 0 54 54 48 9 HEAT repeat V-ATPase_H_N PF03224.14 EKX38812.1 - 5.7e-39 134.2 11.6 1.1e-06 28.2 0.8 16.4 3 3 9 14 14 14 10 V-ATPase subunit H Adaptin_N PF01602.20 EKX38812.1 - 3e-28 98.7 73.6 6.1e-06 25.1 1.8 14.1 2 2 6 11 11 11 8 Adaptin N terminal region Atx10homo_assoc PF09759.9 EKX38812.1 - 2.7e-20 72.2 130.9 0.26 11.3 1.4 36.3 24 14 16 44 44 42 8 Spinocerebellar ataxia type 10 protein domain V-ATPase_H_C PF11698.8 EKX38812.1 - 2.3e-15 56.7 32.1 4.4 7.4 0.1 20.9 17 4 7 25 25 24 1 V-ATPase subunit H DUF5578 PF17741.1 EKX38812.1 - 8.9e-14 51.5 76.4 0.0074 15.7 0.7 20.0 7 6 12 22 22 22 8 Family of unknown function (DUF5578) UNC45-central PF11701.8 EKX38812.1 - 7.3e-11 42.3 26.6 3.6 7.5 0.0 15.8 14 4 2 16 16 15 1 Myosin-binding striated muscle assembly central DUF3361 PF11841.8 EKX38812.1 - 8.9e-11 42.0 100.1 0.11 12.4 0.3 24.3 11 8 14 30 30 30 5 Domain of unknown function (DUF3361) Vac14_Fab1_bd PF12755.7 EKX38812.1 - 1e-07 32.4 1.8 4.2 8.0 0.0 10.5 9 2 2 11 11 11 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EKX38812.1 - 2.8e-07 30.3 32.0 3.1 7.3 0.0 16.3 16 3 4 20 20 20 2 CLASP N terminal CTNNBL PF08216.11 EKX38812.1 - 0.00073 19.7 16.7 14 6.0 0.0 11.7 14 1 1 15 15 11 0 Catenin-beta-like, Arm-motif containing nuclear MotCF PF09158.10 EKX38812.1 - 0.004 17.2 4.2 1.2e+02 2.8 0.0 8.2 5 2 2 7 7 7 0 Bacteriophage T4 MotA, C-terminal DUF2113 PF09886.9 EKX38812.1 - 0.021 14.2 0.4 1.5e+02 1.6 0.0 5.6 4 1 1 5 5 5 0 Uncharacterized protein conserved in archaea (DUF2113) Thioredoxin_6 PF13848.6 EKX38812.1 - 0.037 13.9 0.0 67 3.3 0.0 5.9 6 2 1 8 8 7 0 Thioredoxin-like domain CENP-P PF13096.6 EKX38812.1 - 0.04 13.6 3.9 1.2e+02 2.3 0.0 7.9 7 1 0 7 7 6 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P SEN1_N PF12726.7 EKX38812.1 - 0.055 11.7 4.8 9.2 4.3 0.1 6.3 6 1 0 6 6 6 0 SEN1 N terminal Nipped-B_C PF12830.7 EKX38812.1 - 0.07 13.1 33.7 40 4.1 0.0 16.8 23 1 0 23 23 20 0 Sister chromatid cohesion C-terminus Phage_coat PF09063.10 EKX38812.1 - 0.15 12.1 0.4 4.4 7.3 0.0 3.6 3 0 0 3 3 2 0 Phage PP7 coat protein Phage_mat-A PF03863.13 EKX38812.1 - 0.16 10.9 0.0 4.4 6.1 0.0 3.1 3 1 0 3 3 3 0 Phage maturation protein Ecm29 PF13001.7 EKX38812.1 - 0.53 8.9 7.6 1 8.0 0.0 5.3 5 0 0 5 5 5 0 Proteasome stabiliser RTTN_N PF14726.6 EKX38812.1 - 0.73 10.7 9.5 39 5.1 0.1 7.5 7 1 0 7 7 6 0 Rotatin, an armadillo repeat protein, centriole functioning RTP1_C1 PF10363.9 EKX38812.1 - 2.3 8.4 44.7 1.2 9.4 0.1 14.1 18 2 0 18 18 12 0 Required for nuclear transport of RNA pol II C-terminus 1 CoA_binding_3 PF13727.6 EKX38812.1 - 4.4 7.3 10.2 47 3.9 0.1 6.7 8 1 1 9 9 7 0 CoA-binding domain PTCB-BRCT PF12738.7 EKX38813.1 - 0.0094 15.9 0.2 0.04 13.9 0.1 2.0 1 1 1 2 2 2 1 twin BRCT domain Arm PF00514.23 EKX38814.1 - 1.7e-18 66.0 0.7 3.1e-07 30.2 0.0 3.6 3 0 0 3 3 3 3 Armadillo/beta-catenin-like repeat MMR_HSR1_C PF08438.10 EKX38815.1 - 0.0085 16.7 0.0 0.025 15.1 0.0 1.8 1 0 0 1 1 1 1 GTPase of unknown function C-terminal AF-4 PF05110.13 EKX38817.1 - 6.3 4.7 65.5 8.4 4.3 65.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Mito_carr PF00153.27 EKX38819.1 - 6.7e-27 93.3 3.4 5.9e-18 64.6 0.1 3.9 2 1 1 3 3 3 3 Mitochondrial carrier protein S6PP PF05116.13 EKX38820.1 - 8.8e-35 120.4 0.0 2.4e-34 119.0 0.0 1.6 1 1 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 EKX38820.1 - 3.3e-18 66.4 0.0 1.3e-08 34.9 0.0 2.3 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase PCI PF01399.27 EKX38821.1 - 3.2e-05 24.4 0.0 9.5e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 PCI domain KxDL PF10241.9 EKX38821.1 - 0.0016 18.7 0.4 0.0036 17.5 0.4 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein Laminin_II PF06009.12 EKX38821.1 - 0.079 13.0 0.3 0.14 12.1 0.3 1.5 1 0 0 1 1 1 0 Laminin Domain II ATG16 PF08614.11 EKX38821.1 - 0.11 12.8 2.2 0.18 12.0 2.2 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) zf-RING_2 PF13639.6 EKX38822.1 - 3.7e-13 49.6 5.7 6.5e-13 48.8 5.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX38822.1 - 3.8e-10 39.5 6.5 6.3e-10 38.7 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX38822.1 - 1.3e-08 34.9 7.2 5.6e-08 33.0 7.2 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EKX38822.1 - 2.7e-08 33.7 0.8 2.7e-08 33.7 0.8 1.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EKX38822.1 - 8.4e-08 32.0 5.6 1.3e-07 31.3 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EKX38822.1 - 1.2e-07 31.3 1.6 1.2e-07 31.3 1.6 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EKX38822.1 - 2.3e-07 30.5 3.3 3.5e-07 30.0 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX38822.1 - 2.4e-07 30.6 3.8 4e-07 29.9 3.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EKX38822.1 - 1.3e-05 25.0 3.6 2.1e-05 24.2 3.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EKX38822.1 - 0.00033 20.7 3.4 0.0011 19.0 3.4 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EKX38822.1 - 0.0062 16.1 4.5 0.018 14.6 4.5 1.7 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type Rad50_zn_hook PF04423.14 EKX38822.1 - 0.0099 15.7 0.1 0.25 11.2 0.0 2.6 2 0 0 2 2 2 1 Rad50 zinc hook motif RINGv PF12906.7 EKX38822.1 - 0.025 14.7 3.0 0.076 13.2 3.0 1.9 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 EKX38822.1 - 0.038 14.2 4.3 0.13 12.5 4.4 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Di19 PF05605.12 EKX38822.1 - 0.07 13.4 1.1 8.6 6.7 0.7 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Rtf2 PF04641.12 EKX38822.1 - 0.19 11.0 2.7 0.22 10.9 0.3 2.0 2 0 0 2 2 2 0 Rtf2 RING-finger zf-HC5HC2H PF13771.6 EKX38822.1 - 0.3 11.4 2.4 0.23 11.8 0.4 1.7 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-RING-like PF08746.11 EKX38822.1 - 0.34 11.2 3.4 0.68 10.3 3.4 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 EKX38822.1 - 0.69 9.8 8.0 0.32 10.8 5.2 1.9 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 EKX38822.1 - 0.76 9.5 4.7 2.6 7.8 4.8 1.9 1 1 0 1 1 1 0 P-11 zinc finger Prok-RING_1 PF14446.6 EKX38822.1 - 0.77 9.7 6.0 3.6 7.6 2.5 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-WRNIP1_ubi PF18279.1 EKX38822.1 - 6.8 7.6 6.6 1.2e+02 3.7 0.0 3.2 2 1 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Pkinase PF00069.25 EKX38823.1 - 9.1e-73 244.9 0.0 1.1e-72 244.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX38823.1 - 6.8e-44 150.1 0.0 8.3e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX38823.1 - 8.2e-10 38.5 0.0 1.2e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EKX38823.1 - 3.4e-06 26.8 0.0 5.5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EKX38823.1 - 0.00025 20.5 0.1 0.00058 19.3 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX38823.1 - 0.0022 18.0 0.5 0.005 16.8 0.4 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EKX38823.1 - 0.0065 15.5 0.0 0.0094 14.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EKX38823.1 - 0.032 13.8 0.1 0.1 12.2 0.1 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EKX38823.1 - 0.034 12.9 0.0 0.078 11.7 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Choline_kinase PF01633.20 EKX38823.1 - 0.17 11.4 0.4 0.45 10.1 0.4 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase Tim17 PF02466.19 EKX38824.1 - 1.4e-24 86.6 11.4 2e-24 86.1 11.1 1.4 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF5326 PF17260.2 EKX38824.1 - 1.7 8.9 4.4 0.37 11.0 0.4 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5326) Helicase_C PF00271.31 EKX38827.1 - 1.6e-10 41.3 0.0 8.4e-09 35.8 0.0 3.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EKX38827.1 - 5.3e-09 36.1 0.3 3.1e-08 33.6 0.1 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EKX38827.1 - 0.00013 22.0 0.0 0.022 14.7 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit HHH_5 PF14520.6 EKX38827.1 - 0.0024 18.4 0.1 0.008 16.8 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF4332 PF14229.6 EKX38827.1 - 0.005 17.1 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) QSregVF_b PF12843.7 EKX38827.1 - 0.16 11.8 0.0 0.47 10.4 0.0 1.8 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor Fructosamin_kin PF03881.14 EKX38828.1 - 2.6e-68 230.4 0.0 4.1e-68 229.7 0.0 1.3 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EKX38828.1 - 2e-07 31.2 0.0 4.2e-07 30.1 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family tRNA-synt_2 PF00152.20 EKX38829.1 - 2.1e-78 263.6 0.0 2.8e-78 263.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EKX38829.1 - 5.6e-09 35.9 0.1 1.5e-08 34.5 0.0 1.7 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EKX38829.1 - 2.1e-07 30.7 0.1 9.2e-05 22.0 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) Methyltransf_23 PF13489.6 EKX38829.1 - 0.058 13.2 0.0 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Nop14 PF04147.12 EKX38829.1 - 0.43 8.7 17.1 0.6 8.2 17.1 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EKX38829.1 - 8.1 4.6 17.1 11 4.1 17.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Methyltransf_25 PF13649.6 EKX38830.1 - 1.7e-11 44.7 0.0 4.1e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX38830.1 - 2.1e-11 44.3 0.0 4.1e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX38830.1 - 3.9e-11 43.0 0.0 6.1e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX38830.1 - 5.5e-11 42.6 0.0 8.8e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX38830.1 - 2.7e-10 40.9 0.0 4.9e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EKX38830.1 - 4.5e-05 22.9 0.0 6.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 EKX38830.1 - 6.9e-05 21.9 0.0 9.4e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) RrnaAD PF00398.20 EKX38830.1 - 0.021 13.9 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_16 PF10294.9 EKX38830.1 - 0.035 13.8 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase VanW PF04294.13 EKX38830.1 - 0.046 13.4 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 VanW like protein Methyltransf_15 PF09445.10 EKX38830.1 - 0.07 12.7 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Spermine_synth PF01564.17 EKX38830.1 - 0.089 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Spermine/spermidine synthase domain NAD_binding_7 PF13241.6 EKX38830.1 - 0.11 12.9 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 EKX38830.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Kinesin PF00225.23 EKX38831.1 - 1.1e-97 327.0 0.1 3e-97 325.5 0.1 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX38831.1 - 9.1e-52 175.0 0.0 5e-51 172.6 0.0 2.4 1 0 0 1 1 1 1 Microtubule binding DUF3584 PF12128.8 EKX38831.1 - 0.00092 16.9 63.8 0.016 12.8 49.6 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3584) Golgin_A5 PF09787.9 EKX38831.1 - 0.0015 18.0 19.5 0.0015 18.0 19.5 3.8 2 1 2 4 4 4 1 Golgin subfamily A member 5 PI_PP_I PF18363.1 EKX38831.1 - 0.014 15.6 2.5 0.042 14.0 0.4 2.8 2 1 0 2 2 2 0 Phosphoinositide phosphatase insertion domain UPF0242 PF06785.11 EKX38831.1 - 0.049 13.7 69.0 0.4 10.8 17.9 3.7 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Spuma_A9PTase PF03539.14 EKX38831.1 - 0.13 12.4 0.7 0.34 11.0 0.7 1.7 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) DUF4407 PF14362.6 EKX38831.1 - 0.19 11.0 54.5 0.45 9.8 22.3 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 EKX38831.1 - 0.24 10.4 62.1 0.11 11.5 23.2 3.6 2 1 2 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 HOOK PF05622.12 EKX38831.1 - 0.33 9.0 68.0 0.13 10.4 37.2 2.2 1 1 1 2 2 2 0 HOOK protein ATG16 PF08614.11 EKX38831.1 - 0.5 10.5 81.7 1.5 9.0 23.4 4.6 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Filament PF00038.21 EKX38831.1 - 1 8.9 69.9 0.061 12.9 17.5 5.0 2 1 3 5 5 5 0 Intermediate filament protein Spc7 PF08317.11 EKX38831.1 - 1.8 7.4 77.3 1.1 8.1 30.5 4.5 2 1 3 5 5 5 0 Spc7 kinetochore protein CALCOCO1 PF07888.11 EKX38831.1 - 1.9 7.3 74.1 0.098 11.5 35.7 2.4 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Fez1 PF06818.15 EKX38831.1 - 2.3 8.6 70.6 0.14 12.6 22.3 4.0 2 1 2 4 4 4 0 Fez1 DUF1664 PF07889.12 EKX38831.1 - 3.3 7.8 46.3 0.44 10.6 1.2 5.8 2 1 4 6 6 6 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EKX38831.1 - 10 6.2 36.7 2.9 7.9 2.2 5.1 1 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus EF-hand_8 PF13833.6 EKX38832.1 - 6.7e-11 41.9 2.7 9.2e-09 35.0 0.2 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX38832.1 - 9.5e-10 37.3 1.0 0.00018 20.8 0.1 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX38832.1 - 1.1e-09 37.4 1.1 0.00021 21.0 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EKX38832.1 - 1.5e-09 38.2 0.4 1.7e-09 38.0 0.4 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX38832.1 - 1.2e-05 24.5 2.4 0.023 14.2 0.1 2.1 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 EKX38832.1 - 0.0033 17.7 0.0 0.0034 17.7 0.0 1.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.7 EKX38832.1 - 0.01 15.8 0.1 0.023 14.7 0.1 1.6 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 EKX38832.1 - 0.055 13.7 0.1 0.071 13.3 0.1 1.2 1 0 0 1 1 1 0 Dockerin type I domain TIG PF01833.24 EKX38834.1 - 5.5e-77 253.9 64.6 1.6e-05 24.9 0.0 20.0 20 1 0 20 20 20 17 IPT/TIG domain TIG_plexin PF17960.1 EKX38834.1 - 1.4e-19 69.8 0.0 0.44 10.6 0.0 12.7 14 0 0 14 14 14 5 TIG domain BNR PF02012.20 EKX38834.1 - 0.17 12.0 8.1 13 6.2 0.1 5.0 4 0 0 4 4 4 0 BNR/Asp-box repeat Qn_am_d_aIII PF09099.10 EKX38834.1 - 0.52 10.7 3.2 18 5.8 0.1 4.9 6 0 0 6 6 6 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III TIG PF01833.24 EKX38835.1 - 0.00053 20.0 0.2 1.9 8.6 0.0 2.7 3 0 0 3 3 3 2 IPT/TIG domain TIG PF01833.24 EKX38836.1 - 4.1e-37 126.1 22.6 6.7e-11 42.1 0.4 6.2 6 0 0 6 6 6 6 IPT/TIG domain TIG_plexin PF17960.1 EKX38836.1 - 1.5e-08 34.6 0.0 0.038 14.0 0.0 4.3 6 0 0 6 6 6 2 TIG domain TIG PF01833.24 EKX38837.1 - 0.02 14.9 1.7 6.7 6.9 0.0 3.9 3 1 0 3 3 3 0 IPT/TIG domain Abhydrolase_1 PF00561.20 EKX38838.1 - 5.7e-11 42.6 0.0 9.8e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EKX38838.1 - 1.8e-09 37.2 0.0 2.5e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EKX38838.1 - 7.1e-08 33.3 0.0 1e-07 32.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.22 EKX38838.1 - 0.021 14.8 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Cutinase LSM PF01423.22 EKX38840.1 - 0.075 12.7 0.4 0.33 10.7 0.1 2.1 2 1 0 2 2 2 0 LSM domain Exonuc_VII_L PF02601.15 EKX38842.1 - 0.11 12.0 4.6 0.15 11.6 4.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3552 PF12072.8 EKX38842.1 - 1.2 8.5 20.4 2.3 7.6 20.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) FAM76 PF16046.5 EKX38842.1 - 3.1 7.1 19.8 2.6 7.3 8.1 2.3 1 1 1 2 2 2 0 FAM76 protein DUF4407 PF14362.6 EKX38842.1 - 5.3 6.3 11.7 1.8 7.8 8.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Sec2p PF06428.11 EKX38844.1 - 0.25 11.3 29.6 5.1 7.1 8.2 4.2 2 1 2 4 4 4 0 GDP/GTP exchange factor Sec2p Exonuc_VII_L PF02601.15 EKX38844.1 - 0.76 9.3 11.6 1.1 8.7 11.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit FOXP-CC PF16159.5 EKX38844.1 - 2.3 8.9 10.7 3.8 8.2 0.3 3.1 2 1 1 3 3 3 0 FOXP coiled-coil domain DUF1993 PF09351.10 EKX38844.1 - 2.4 8.3 9.7 3.9 7.6 3.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) Vps35 PF03635.17 EKX38846.1 - 9.2e-267 887.3 0.0 1.1e-266 887.0 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 CDC45 PF02724.14 EKX38847.1 - 0.017 13.4 3.7 0.019 13.3 3.7 1.1 1 0 0 1 1 1 0 CDC45-like protein TrkA_N PF02254.18 EKX38847.1 - 0.072 13.3 2.0 0.48 10.7 0.0 2.5 3 0 0 3 3 3 0 TrkA-N domain TFIIA PF03153.13 EKX38847.1 - 0.69 9.8 10.5 0.69 9.8 10.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2457 PF10446.9 EKX38847.1 - 1.2 8.2 22.2 1.7 7.7 22.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF2076 PF09849.9 EKX38847.1 - 2 8.4 14.7 3.2 7.7 14.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) NOA36 PF06524.12 EKX38847.1 - 4.2 6.6 21.2 5.9 6.1 21.2 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 EKX38847.1 - 8.1 4.5 11.7 9.4 4.3 11.7 1.1 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 EKX38847.1 - 9.1 6.3 7.5 16 5.5 7.5 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal RHD3 PF05879.12 EKX38848.1 - 9.2e-100 334.9 0.1 1e-99 334.7 0.1 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 EKX38848.1 - 1.2e-06 28.0 0.0 1.7e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 EKX38848.1 - 1.6e-05 24.9 0.0 3.8e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EKX38848.1 - 9.5e-05 22.5 0.2 0.00021 21.4 0.2 1.5 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 EKX38848.1 - 0.004 17.4 0.1 0.011 15.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain G-alpha PF00503.20 EKX38848.1 - 0.078 12.1 0.0 0.14 11.3 0.0 1.4 1 1 0 1 1 1 0 G-protein alpha subunit Roc PF08477.13 EKX38848.1 - 0.082 13.1 0.2 0.18 12.0 0.2 1.6 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 EKX38848.1 - 0.087 12.9 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EKX38848.1 - 0.089 12.7 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 EKX38848.1 - 0.096 13.2 0.1 0.19 12.3 0.1 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 EKX38848.1 - 0.11 12.3 0.1 0.36 10.6 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 EKX38848.1 - 0.19 11.3 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain RHD3 PF05879.12 EKX38849.1 - 7.1e-17 60.8 9.8 1.4e-09 36.7 4.0 2.0 1 1 1 2 2 2 2 Root hair defective 3 GTP-binding protein (RHD3) DUF2545 PF10810.8 EKX38849.1 - 0.085 13.0 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2545) Hydrolase_like PF13242.6 EKX38849.1 - 0.17 12.0 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Arm PF00514.23 EKX38850.1 - 0.013 15.6 0.3 0.013 15.6 0.3 1.9 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EKX38850.1 - 0.034 14.5 1.0 0.38 11.2 0.1 2.5 2 0 0 2 2 2 0 HEAT repeats HEAT PF02985.22 EKX38850.1 - 2 8.9 3.7 1 9.8 0.1 2.4 2 0 0 2 2 2 0 HEAT repeat FYDLN_acid PF09538.10 EKX38850.1 - 9.5 7.0 7.7 18 6.1 0.3 3.1 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) bZIP_1 PF00170.21 EKX38851.1 - 7.1e-10 38.8 25.2 3.1e-07 30.4 5.0 3.3 2 1 1 3 3 3 2 bZIP transcription factor bZIP_2 PF07716.15 EKX38851.1 - 1.1e-06 28.6 2.3 1.1e-06 28.6 2.3 3.9 4 0 0 4 4 4 3 Basic region leucine zipper bZIP_Maf PF03131.17 EKX38851.1 - 0.00048 20.6 21.0 0.031 14.8 6.6 3.5 2 1 1 3 3 3 3 bZIP Maf transcription factor DUF2175 PF09943.9 EKX38851.1 - 1.6 9.1 4.2 1.5 9.2 1.3 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DUF1664 PF07889.12 EKX38851.1 - 2.1 8.4 7.3 1.6 8.8 1.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SelR PF01641.18 EKX38852.1 - 8.3e-43 145.3 0.2 9.3e-43 145.2 0.2 1.0 1 0 0 1 1 1 1 SelR domain TF_Zn_Ribbon PF08271.12 EKX38852.1 - 0.00035 20.0 0.2 0.0055 16.2 0.0 2.3 2 0 0 2 2 2 1 TFIIB zinc-binding zf-ribbon_3 PF13248.6 EKX38852.1 - 0.01 15.3 0.9 4.6 6.8 0.1 2.5 2 0 0 2 2 2 2 zinc-ribbon domain DUF678 PF05077.12 EKX38852.1 - 0.014 15.5 0.1 3.7 7.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF678) ADD_ATRX PF17981.1 EKX38852.1 - 0.024 14.5 0.0 8.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Cysteine Rich ADD domain DZR PF12773.7 EKX38852.1 - 0.032 14.3 0.4 0.24 11.4 0.4 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-RRN7 PF11781.8 EKX38852.1 - 0.038 13.7 2.8 0.94 9.2 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 GFA PF04828.14 EKX38852.1 - 0.039 14.3 1.1 0.34 11.3 0.1 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 EKX38852.1 - 0.046 13.6 1.2 13 5.8 0.3 2.6 2 0 0 2 2 2 0 Nudix N-terminal DUF4428 PF14471.6 EKX38852.1 - 0.05 13.5 0.2 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) Yippee-Mis18 PF03226.14 EKX38852.1 - 0.056 13.7 0.0 0.087 13.0 0.0 1.3 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zn-ribbon_8 PF09723.10 EKX38852.1 - 0.072 13.2 0.4 5.5 7.2 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_10 PF10058.9 EKX38852.1 - 0.073 12.8 0.1 5.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-C4_Topoisom PF01396.19 EKX38852.1 - 0.08 12.7 1.6 3.3 7.6 0.1 2.4 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_2 PF13240.6 EKX38852.1 - 0.15 11.9 1.7 31 4.5 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.6 EKX38852.1 - 0.19 11.5 1.2 5 7.0 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Prim_Zn_Ribbon PF08273.12 EKX38852.1 - 0.84 10.0 9.2 3.2 8.1 0.1 2.8 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase LRR_9 PF14580.6 EKX38853.1 - 5.7e-12 45.5 1.9 1.4e-11 44.2 0.9 2.1 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 EKX38853.1 - 1.2e-09 38.3 2.6 0.0001 22.6 0.1 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX38853.1 - 0.00011 21.8 3.7 0.021 14.6 0.3 3.2 3 1 1 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 EKX38853.1 - 1.7 9.5 3.3 55 4.9 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich Repeat Pkinase PF00069.25 EKX38854.1 - 2.8e-57 194.1 0.0 3.3e-57 193.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX38854.1 - 3.2e-38 131.5 0.0 3.8e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX38854.1 - 6.7e-05 22.3 0.0 0.0001 21.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EKX38854.1 - 0.0024 17.2 0.3 0.0041 16.5 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EKX38854.1 - 0.019 14.5 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 EKX38854.1 - 0.15 10.8 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase GATase_2 PF00310.21 EKX38856.1 - 0.037 12.7 0.8 0.042 12.5 0.8 1.1 1 0 0 1 1 1 0 Glutamine amidotransferases class-II DUF4105 PF13387.6 EKX38856.1 - 0.038 13.6 0.5 0.046 13.4 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) NYAP_N PF15439.6 EKX38856.1 - 0.06 12.5 5.6 0.069 12.4 5.6 1.1 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Glyco_tranf_2_4 PF13704.6 EKX38856.1 - 0.064 13.8 0.2 0.21 12.1 0.0 2.0 1 1 1 2 2 2 0 Glycosyl transferase family 2 RNase_H2_suC PF08615.11 EKX38856.1 - 0.087 13.0 0.7 0.11 12.6 0.7 1.2 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) RRN9 PF10680.9 EKX38856.1 - 0.093 13.0 1.3 0.15 12.3 1.3 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor FAM195 PF14799.6 EKX38856.1 - 0.11 12.9 7.6 0.15 12.4 7.6 1.2 1 0 0 1 1 1 0 FAM195 family Roughex PF06020.11 EKX38856.1 - 0.12 11.4 3.9 0.14 11.2 3.9 1.1 1 0 0 1 1 1 0 Drosophila roughex protein DUF3915 PF13054.6 EKX38856.1 - 0.24 11.4 0.5 0.39 10.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DEC-1_N PF04625.13 EKX38856.1 - 0.57 9.1 4.0 0.69 8.9 4.0 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region UVR PF02151.19 EKX38857.1 - 1.1e-25 88.6 53.2 3.8e-07 29.6 3.8 4.3 4 0 0 4 4 4 4 UvrB/uvrC motif Phasin_2 PF09361.10 EKX38857.1 - 0.0045 17.2 4.4 1 9.7 0.5 2.4 2 0 0 2 2 2 2 Phasin protein Glyco_tranf_2_4 PF13704.6 EKX38857.1 - 0.0045 17.5 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 ECSIT_C PF14784.6 EKX38857.1 - 0.021 15.2 0.1 0.054 13.8 0.1 1.6 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein DUF4208 PF13907.6 EKX38857.1 - 0.35 11.3 14.5 0.19 12.2 0.6 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4208) DUF1192 PF06698.11 EKX38857.1 - 2.6 8.2 20.6 11 6.1 0.3 4.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) G-gamma PF00631.22 EKX38857.1 - 5 7.2 13.4 72 3.5 0.2 4.8 4 0 0 4 4 4 0 GGL domain MFS_1 PF07690.16 EKX38858.1 - 6.9e-24 84.4 18.6 6.9e-22 77.8 12.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EKX38858.1 - 0.0008 17.9 6.4 0.0008 17.9 6.4 2.2 2 1 0 2 2 2 1 Transmembrane secretion effector HA PF03457.14 EKX38860.1 - 1.9e-18 66.5 3.5 3e-13 49.9 0.2 2.1 2 0 0 2 2 2 2 Helicase associated domain DUF3523 PF12037.8 EKX38860.1 - 0.0082 15.5 0.1 2.8 7.3 0.0 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF3523) 4HBT PF03061.22 EKX38862.1 - 0.0048 17.2 0.1 0.02 15.2 0.0 2.0 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT_2 PF13279.6 EKX38862.1 - 0.098 13.1 0.0 0.16 12.4 0.0 1.5 1 1 0 1 1 1 0 Thioesterase-like superfamily CRCB PF02537.15 EKX38863.1 - 3.6e-07 30.4 0.7 5.2e-07 29.9 0.7 1.2 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) ECF-ribofla_trS PF07155.12 EKX38863.1 - 0.0057 16.7 0.1 0.0071 16.4 0.1 1.1 1 0 0 1 1 1 1 ECF-type riboflavin transporter, S component EZH2_N PF18601.1 EKX38864.1 - 0.0058 16.9 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 EZH2 N-terminal domain ISN1 PF06437.11 EKX38865.1 - 6.3e-86 288.8 0.0 7.7e-86 288.6 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase DUF2423 PF10338.9 EKX38866.1 - 5e-06 26.6 0.6 5e-06 26.6 0.6 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Laps PF10169.9 EKX38866.1 - 0.0086 16.6 1.2 0.0086 16.6 1.2 2.3 2 0 0 2 2 2 1 Learning-associated protein WT1 PF02165.15 EKX38866.1 - 0.11 11.8 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Wilm's tumour protein Alliinase_C PF04864.13 EKX38867.1 - 3.6e-64 216.9 0.0 4.5e-64 216.6 0.0 1.1 1 0 0 1 1 1 1 Allinase Aminotran_1_2 PF00155.21 EKX38867.1 - 2.2e-07 30.4 0.0 2.5e-06 26.9 0.0 2.4 1 1 0 1 1 1 1 Aminotransferase class I and II EGF_alliinase PF04863.13 EKX38867.1 - 3.4 8.1 9.4 1 9.8 6.1 1.9 2 0 0 2 2 2 0 Alliinase EGF-like domain PG_binding_3 PF09374.10 EKX38871.1 - 1.7e-05 25.0 0.0 0.56 10.5 0.0 3.4 2 1 1 3 3 3 3 Predicted Peptidoglycan domain PG_binding_1 PF01471.18 EKX38871.1 - 0.0024 18.0 0.0 0.17 12.1 0.0 2.7 2 0 0 2 2 2 1 Putative peptidoglycan binding domain Talin_middle PF09141.10 EKX38874.1 - 0.021 14.9 2.6 1.8 8.5 0.7 2.4 2 0 0 2 2 2 0 Talin, middle domain LRR_8 PF13855.6 EKX38875.1 - 5.7e-35 118.9 58.5 4e-10 39.3 6.2 7.9 6 1 2 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 EKX38875.1 - 2.1e-27 94.7 68.6 2.3e-05 24.7 1.6 9.5 6 2 2 10 10 10 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX38875.1 - 7.1e-11 41.9 22.0 0.00068 19.2 0.7 5.3 2 1 1 5 5 5 4 Leucine-rich repeat LRR_5 PF13306.6 EKX38875.1 - 1e-07 31.9 4.0 0.00047 20.1 0.4 3.4 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EKX38875.1 - 0.024 15.1 47.5 6.5 7.7 1.3 13.1 12 3 0 12 12 12 0 Leucine Rich Repeat LRR_6 PF13516.6 EKX38875.1 - 9.8 6.5 57.0 5.5 7.3 0.1 12.3 14 0 0 14 14 14 0 Leucine Rich repeat DUF4045 PF13254.6 EKX38876.1 - 0.12 12.0 39.9 0.17 11.5 39.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CCSAP PF15748.5 EKX38876.1 - 0.36 11.0 56.4 0.48 10.6 56.4 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF572 PF04502.13 EKX38876.1 - 1.3 8.6 43.0 1.7 8.2 43.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) XRN_M PF17846.1 EKX38876.1 - 1.6 7.6 34.9 1.9 7.4 34.9 1.2 1 0 0 1 1 1 0 Xrn1 helical domain SOBP PF15279.6 EKX38876.1 - 7.2 7.1 46.5 10 6.6 46.5 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein PAT1 PF09770.9 EKX38876.1 - 7.9 4.6 74.4 8.6 4.5 74.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MAP7 PF05672.11 EKX38876.1 - 8.2 6.1 83.7 10 5.8 83.7 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DUF2151 PF10221.9 EKX38876.1 - 9.5 4.7 31.5 10 4.6 31.5 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator CDC45 PF02724.14 EKX38876.1 - 9.9 4.3 50.1 13 3.9 50.1 1.1 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.32 EKX38878.1 - 4.8e-26 90.5 7.2 3e-05 24.7 0.2 10.4 10 0 0 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX38878.1 - 6.7e-12 45.5 0.0 0.7 10.2 0.0 8.2 5 3 4 9 9 9 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EKX38878.1 - 7.2e-05 23.1 0.3 3 8.5 0.0 5.6 6 1 1 7 7 7 1 PQQ-like domain UPF0020 PF01170.18 EKX38878.1 - 0.032 13.9 0.3 0.068 12.8 0.3 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 ubiquitin PF00240.23 EKX38878.1 - 1.1 9.1 4.5 3.5 7.5 0.4 3.4 3 0 0 3 3 3 0 Ubiquitin family DUF883 PF05957.13 EKX38878.1 - 2.9 8.6 18.6 0.1 13.2 3.7 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Muted PF14942.6 EKX38878.1 - 3.2 8.1 39.8 1.3 9.4 15.1 3.0 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein PAE PF03283.13 EKX38879.1 - 5.1e-34 117.9 0.1 7.9e-31 107.5 0.2 2.1 1 1 1 2 2 2 2 Pectinacetylesterase LSDAT_euk PF18139.1 EKX38880.1 - 5.2e-44 150.6 0.0 8.7e-43 146.6 0.0 2.3 1 1 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 EKX38880.1 - 3.2e-21 75.5 0.0 8.1e-10 38.3 0.0 3.0 2 1 0 2 2 2 2 SLOG in TRPM, prokaryote AA_kinase PF00696.28 EKX38882.1 - 1.9e-38 132.5 3.0 2.3e-38 132.2 2.1 1.5 2 0 0 2 2 2 1 Amino acid kinase family PUA PF01472.20 EKX38882.1 - 4.8e-06 26.4 0.1 2e-05 24.5 0.3 2.0 2 0 0 2 2 2 1 PUA domain Myb_DNA-binding PF00249.31 EKX38883.1 - 2.4e-07 30.8 0.1 1e-06 28.8 0.1 1.9 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EKX38884.1 - 4.5e-07 29.9 0.0 2.3e-06 27.7 0.0 2.2 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EKX38885.1 - 2.2e-08 34.1 0.0 3.3e-07 30.4 0.0 2.5 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EKX38885.1 - 0.041 13.8 0.1 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 Myb DNA-binding like Myb_DNA-binding PF00249.31 EKX38886.1 - 4.4e-07 30.0 0.0 1.7e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 Myb-like DNA-binding domain cNMP_binding PF00027.29 EKX38887.1 - 8.4e-09 35.4 0.2 2.1e-08 34.1 0.0 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain RskA PF10099.9 EKX38887.1 - 0.00059 20.2 26.0 13 6.0 26.0 3.5 1 1 0 1 1 1 1 Anti-sigma-K factor rskA BTK PF00779.19 EKX38887.1 - 0.033 14.0 17.6 0.092 12.6 5.0 3.8 3 0 0 3 3 3 0 BTK motif PAT1 PF09770.9 EKX38887.1 - 0.035 12.4 56.1 0.059 11.6 56.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Endostatin PF06482.11 EKX38887.1 - 0.11 11.9 27.6 0.27 10.6 27.6 1.7 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin GREB1 PF15782.5 EKX38887.1 - 0.11 9.6 32.6 0.18 8.9 32.6 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4045 PF13254.6 EKX38887.1 - 0.33 10.5 35.6 0.034 13.8 28.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Dapper PF15268.6 EKX38887.1 - 2.3 7.0 45.8 0.064 12.1 38.5 1.9 2 0 0 2 2 2 0 Dapper SOBP PF15279.6 EKX38887.1 - 3.1 8.3 32.6 1.1 9.8 29.1 2.0 2 0 0 2 2 2 0 Sine oculis-binding protein Exonuc_VII_L PF02601.15 EKX38887.1 - 7.2 6.1 36.3 9.9 5.6 35.6 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit Dicty_REP PF05086.12 EKX38887.1 - 9.4 4.1 28.6 16 3.3 28.6 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SufE PF02657.15 EKX38889.1 - 1.7e-14 53.7 0.0 1.8e-14 53.6 0.0 1.0 1 0 0 1 1 1 1 Fe-S metabolism associated domain tRNA_Me_trans PF03054.16 EKX38890.1 - 2.3e-113 378.6 0.0 2.7e-113 378.4 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.21 EKX38890.1 - 0.0001 22.1 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.17 EKX38890.1 - 0.0022 17.2 0.0 1.8 7.6 0.0 2.3 2 1 0 2 2 2 2 NAD synthase ThiI PF02568.14 EKX38890.1 - 0.0068 16.0 0.0 0.024 14.2 0.0 1.8 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) WWE PF02825.20 EKX38891.1 - 0.00031 21.3 0.0 0.00061 20.3 0.0 1.5 1 0 0 1 1 1 1 WWE domain SK_channel PF03530.14 EKX38892.1 - 1.4e-11 44.4 0.1 1.4e-11 44.4 0.1 2.6 2 1 1 3 3 3 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.16 EKX38892.1 - 6.4e-09 35.7 10.0 6.4e-09 35.7 10.0 2.6 2 2 0 2 2 2 1 Ion channel Lig_chan PF00060.26 EKX38892.1 - 0.00016 21.5 0.4 0.00016 21.5 0.4 2.4 3 0 0 3 3 3 1 Ligand-gated ion channel IQ PF00612.27 EKX38892.1 - 0.003 17.2 0.3 0.0076 16.0 0.3 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Ion_trans PF00520.31 EKX38892.1 - 0.0053 16.0 27.0 0.069 12.4 27.0 2.4 1 1 0 1 1 1 1 Ion transport protein Ank_5 PF13857.6 EKX38895.1 - 6.7e-16 58.2 1.7 2.2e-08 34.2 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX38895.1 - 6.2e-13 49.1 0.1 9e-13 48.6 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX38895.1 - 4.7e-10 39.5 1.0 5.6e-05 23.4 0.8 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EKX38895.1 - 1.4e-09 37.4 0.2 4.5e-05 23.5 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EKX38895.1 - 3.7e-09 37.0 0.6 0.0003 21.3 0.0 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) PAF-AH_p_II PF03403.13 EKX38897.1 - 4.6e-55 186.7 0.0 4.2e-51 173.6 0.0 2.3 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EKX38897.1 - 1.5e-05 24.1 0.0 0.0001 21.3 0.0 2.2 2 1 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EKX38897.1 - 0.13 11.3 0.0 0.83 8.6 0.0 2.2 3 0 0 3 3 3 0 Chlorophyllase Hydrolase_4 PF12146.8 EKX38897.1 - 0.2 10.9 0.2 0.81 8.9 0.1 2.0 2 1 1 3 3 3 0 Serine aminopeptidase, S33 KH_8 PF17903.1 EKX38898.1 - 1e-31 108.8 0.1 3.6e-31 107.1 0.0 2.0 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 EKX38898.1 - 0.18 11.7 1.6 1.8 8.4 0.0 3.0 2 1 0 2 2 2 0 KH domain Cas_Csa5 PF09702.10 EKX38898.1 - 0.28 11.5 2.0 1 9.6 1.0 2.2 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csa5) 2OG-FeII_Oxy_2 PF13532.6 EKX38899.1 - 5.6e-24 85.4 0.0 7.8e-23 81.7 0.0 2.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_11 PF08241.12 EKX38899.1 - 0.0015 19.2 1.1 0.62 10.8 0.1 2.8 1 1 1 2 2 2 2 Methyltransferase domain RRM_1 PF00076.22 EKX38899.1 - 0.0025 17.6 0.0 0.0052 16.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_25 PF13649.6 EKX38899.1 - 0.0039 17.9 0.5 0.075 13.7 0.3 2.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX38899.1 - 0.048 13.4 0.4 0.27 11.0 0.3 2.1 1 1 1 2 2 2 0 Methyltransferase domain Ufm1 PF03671.14 EKX38900.1 - 5.9e-39 132.0 0.1 6.6e-39 131.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein APG12 PF04110.13 EKX38900.1 - 0.012 16.0 0.0 0.015 15.7 0.0 1.0 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 GHMP_kinases_N PF00288.26 EKX38902.1 - 8.7e-10 38.7 0.0 2.4e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GalKase_gal_bdg PF10509.9 EKX38902.1 - 0.0069 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature ADH_zinc_N PF00107.26 EKX38903.1 - 2.1e-08 34.2 0.0 4.3e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EKX38903.1 - 0.00014 21.4 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus DUF4653 PF15546.6 EKX38903.1 - 0.038 13.6 0.1 0.071 12.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) FAM176 PF14851.6 EKX38903.1 - 1.4 8.5 8.7 10 5.8 2.9 2.3 2 0 0 2 2 2 0 FAM176 family Beta_propel PF09826.9 EKX38904.1 - 1.2e-95 321.3 0.0 5.6e-52 177.3 0.0 2.9 1 1 1 2 2 2 2 Beta propeller domain DUF2730 PF10805.8 EKX38904.1 - 0.17 12.0 0.1 0.32 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) LRR_6 PF13516.6 EKX38905.1 - 2.4e-38 126.9 14.2 0.00082 19.2 0.1 10.7 11 0 0 11 11 11 9 Leucine Rich repeat LRR_1 PF00560.33 EKX38905.1 - 2.4e-10 39.5 1.6 17 6.4 0.0 8.2 8 1 0 8 8 8 3 Leucine Rich Repeat LRR_4 PF12799.7 EKX38905.1 - 7.6e-06 26.2 7.0 1.3 9.6 0.1 6.3 5 2 3 8 8 8 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX38905.1 - 2.9e-05 23.7 10.9 1.6 8.6 0.7 6.6 4 3 3 7 7 7 3 Leucine rich repeat Zn-C2H2_12 PF18112.1 EKX38906.1 - 0.012 16.1 0.1 0.027 14.9 0.1 1.6 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_4 PF13894.6 EKX38906.1 - 0.042 14.7 2.0 3.8 8.6 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PG_binding_1 PF01471.18 EKX38908.1 - 1e-07 32.1 0.0 4.2e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 Putative peptidoglycan binding domain S-layer PF07752.11 EKX38908.1 - 0.089 11.8 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 S-layer protein IMCp PF12314.8 EKX38909.1 - 0.0042 17.4 46.5 0.088 13.1 9.7 3.3 1 1 2 3 3 3 3 Inner membrane complex protein Herpes_IR6 PF06307.12 EKX38909.1 - 0.11 12.0 10.5 0.014 14.9 3.1 2.9 2 1 1 3 3 3 0 Herpesvirus IR6 protein DUF4488 PF14869.6 EKX38909.1 - 1 9.3 6.1 0.58 10.1 1.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4488) Sushi PF00084.20 EKX38910.1 - 4.2e-46 155.3 40.7 2.1e-09 37.8 0.2 9.2 7 2 2 9 9 9 8 Sushi repeat (SCR repeat) Sec7 PF01369.20 EKX38911.1 - 8.9e-59 198.2 0.2 1.4e-58 197.6 0.2 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EKX38911.1 - 1.2e-07 31.7 0.8 1.2e-07 31.7 0.8 3.3 2 1 1 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF4611 PF15387.6 EKX38911.1 - 0.084 13.1 2.9 0.3 11.3 2.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.10 EKX38911.1 - 0.83 10.1 10.7 2.6 8.5 10.7 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Myc_N PF01056.18 EKX38911.1 - 1 9.2 3.9 2.1 8.2 3.9 1.4 1 0 0 1 1 1 0 Myc amino-terminal region DUF211 PF02680.14 EKX38912.1 - 0.004 17.3 1.5 1.3 9.3 1.2 2.3 2 0 0 2 2 2 1 Uncharacterized ArCR, COG1888 AAA_25 PF13481.6 EKX38912.1 - 0.0042 16.7 0.0 0.015 14.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EKX38912.1 - 0.0065 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein D5_N PF08706.11 EKX38912.1 - 0.0094 16.2 0.6 0.037 14.3 0.0 2.3 2 0 0 2 2 2 1 D5 N terminal like ATPase PF06745.13 EKX38912.1 - 0.016 14.6 0.2 0.08 12.3 0.0 2.2 2 0 0 2 2 2 0 KaiC RHSP PF07999.11 EKX38912.1 - 0.037 12.9 0.0 0.07 11.9 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon hot spot protein Laminin_II PF06009.12 EKX38912.1 - 0.043 13.8 1.7 0.078 13.0 1.7 1.4 1 0 0 1 1 1 0 Laminin Domain II IFT57 PF10498.9 EKX38912.1 - 0.051 12.5 4.9 0.084 11.8 4.9 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 MeaB PF03308.16 EKX38912.1 - 0.065 12.2 0.5 0.22 10.5 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 EKX38912.1 - 0.13 12.7 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Macoilin PF09726.9 EKX38912.1 - 0.35 9.4 7.3 0.52 8.8 7.3 1.1 1 0 0 1 1 1 0 Macoilin family Spc7 PF08317.11 EKX38912.1 - 0.7 8.7 9.8 0.26 10.1 4.5 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein HrpB7 PF09486.10 EKX38912.1 - 1.2 9.5 5.6 0.097 13.1 0.6 1.7 2 0 0 2 2 1 0 Bacterial type III secretion protein (HrpB7) Ank_2 PF12796.7 EKX38913.1 - 2.7e-20 72.7 0.1 2e-10 41.1 0.0 2.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX38913.1 - 2.4e-10 40.7 0.0 3.6e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX38913.1 - 3.6e-10 39.2 0.1 4.2e-05 23.6 0.2 3.3 3 1 1 4 4 4 2 Ankyrin repeat Ank PF00023.30 EKX38913.1 - 2.9e-08 33.8 0.4 6.1e-05 23.3 1.0 3.7 4 1 1 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 EKX38913.1 - 0.00026 21.2 0.3 0.099 13.0 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Na_H_Exchanger PF00999.21 EKX38916.1 - 6.6e-69 232.5 35.6 7.3e-69 232.4 35.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF962 PF06127.11 EKX38916.1 - 0.065 13.3 1.6 0.39 10.8 1.6 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF962) PDZ_6 PF17820.1 EKX38918.1 - 8.8e-31 105.5 1.3 1.1e-09 37.9 0.1 4.5 4 0 0 4 4 4 4 PDZ domain PDZ PF00595.24 EKX38918.1 - 7e-28 96.8 2.0 3.8e-08 33.6 0.2 4.9 4 1 1 5 5 5 4 PDZ domain PDZ_2 PF13180.6 EKX38918.1 - 1.3e-22 79.9 0.1 1e-05 25.8 0.0 4.3 4 0 0 4 4 4 4 PDZ domain CHCH PF06747.13 EKX38919.1 - 0.00094 19.3 3.8 0.38 11.0 0.2 2.3 2 0 0 2 2 2 2 CHCH domain SH3_2 PF07653.17 EKX38919.1 - 0.099 12.3 0.2 0.23 11.2 0.2 1.6 1 1 0 1 1 1 0 Variant SH3 domain SIR2 PF02146.17 EKX38920.1 - 3.6e-35 121.5 0.0 2.8e-33 115.3 0.0 2.1 1 1 0 1 1 1 1 Sir2 family DZR PF12773.7 EKX38920.1 - 0.032 14.2 1.2 0.066 13.3 1.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon Ribosomal_S27e PF01667.17 EKX38920.1 - 0.095 12.4 1.0 0.39 10.5 0.1 2.1 2 0 0 2 2 2 0 Ribosomal protein S27 Glyco_trans_1_4 PF13692.6 EKX38921.1 - 1.2e-08 35.5 0.0 2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EKX38921.1 - 1.2e-08 34.7 0.0 1.9e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EKX38921.1 - 0.0065 16.8 0.1 0.018 15.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Arm PF00514.23 EKX38922.1 - 7.5e-16 57.6 1.0 0.00023 21.1 0.0 4.7 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat DUF3361 PF11841.8 EKX38922.1 - 0.0005 20.0 0.6 0.011 15.7 0.1 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3361) Atx10homo_assoc PF09759.9 EKX38922.1 - 0.0039 17.2 1.0 0.24 11.4 0.0 3.5 3 2 1 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Neurochondrin PF05536.11 EKX38922.1 - 0.012 14.1 0.0 0.024 13.0 0.0 1.5 1 1 0 1 1 1 0 Neurochondrin EF-hand_7 PF13499.6 EKX38923.1 - 9.1e-08 32.4 1.9 0.0022 18.4 0.2 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX38923.1 - 9.8e-07 27.9 4.4 0.00095 18.6 0.2 3.8 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 EKX38923.1 - 4.1e-06 26.3 1.8 0.0076 16.1 0.2 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 EKX38923.1 - 0.0023 17.7 0.1 2.9 7.8 0.3 2.8 2 1 1 3 3 3 3 EF-hand domain pair DUF2730 PF10805.8 EKX38923.1 - 0.01 15.9 2.1 0.018 15.1 1.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) EF-hand_5 PF13202.6 EKX38923.1 - 0.013 15.0 1.7 0.016 14.6 0.2 2.1 2 0 0 2 2 2 0 EF hand DUF2856 PF11043.8 EKX38923.1 - 0.048 13.8 0.7 0.12 12.5 0.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2856) Takusan PF04822.13 EKX38923.1 - 0.051 13.5 1.8 0.096 12.6 1.1 1.8 1 1 0 1 1 1 0 Takusan bZIP_1 PF00170.21 EKX38924.1 - 1.9e-11 43.9 19.5 4.4e-06 26.7 5.0 3.7 2 1 1 3 3 3 3 bZIP transcription factor bZIP_2 PF07716.15 EKX38924.1 - 2.5e-07 30.7 3.2 2.5e-07 30.7 3.2 4.0 3 1 1 4 4 4 2 Basic region leucine zipper bZIP_Maf PF03131.17 EKX38924.1 - 2.8e-05 24.5 16.2 0.04 14.4 0.4 3.4 2 1 1 3 3 3 2 bZIP Maf transcription factor Spc7 PF08317.11 EKX38924.1 - 0.00065 18.7 5.8 0.0011 17.9 5.8 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Pox_A_type_inc PF04508.12 EKX38924.1 - 0.00087 19.0 5.5 0.0048 16.7 0.3 3.1 3 0 0 3 3 3 1 Viral A-type inclusion protein repeat Laminin_II PF06009.12 EKX38924.1 - 0.051 13.6 3.4 0.092 12.8 3.4 1.4 1 0 0 1 1 1 0 Laminin Domain II CENP-F_leu_zip PF10473.9 EKX38924.1 - 0.081 12.9 10.8 0.28 11.2 10.8 1.9 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CorA PF01544.18 EKX38924.1 - 0.084 12.2 1.5 0.18 11.1 1.5 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein TSC22 PF01166.18 EKX38924.1 - 0.089 13.1 2.0 0.67 10.3 0.2 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family Nup54 PF13874.6 EKX38924.1 - 0.13 12.3 7.7 0.083 13.0 4.3 2.0 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Fib_alpha PF08702.10 EKX38924.1 - 0.26 11.4 3.2 0.59 10.3 3.2 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family YabA PF06156.13 EKX38924.1 - 0.33 11.6 5.2 0.2 12.3 1.5 2.3 1 1 1 2 2 2 0 Initiation control protein YabA COG6 PF06419.11 EKX38924.1 - 0.54 8.4 5.3 0.78 7.9 5.3 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 Spc24 PF08286.11 EKX38924.1 - 0.58 10.4 4.3 0.41 10.9 1.3 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Csm1_N PF18504.1 EKX38924.1 - 0.7 10.3 6.8 0.64 10.4 3.5 2.4 1 1 1 2 2 2 0 Csm1 N-terminal domain DUF724 PF05266.14 EKX38924.1 - 0.72 9.6 5.0 1.8 8.4 5.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) UPF0242 PF06785.11 EKX38924.1 - 0.83 9.7 7.3 0.22 11.6 3.9 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Occludin_ELL PF07303.13 EKX38924.1 - 1 10.1 6.3 0.6 10.9 3.5 2.0 2 0 0 2 2 2 0 Occludin homology domain FlaC_arch PF05377.11 EKX38924.1 - 1.1 9.7 4.4 6.3 7.3 3.5 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) GAS PF13851.6 EKX38924.1 - 2.1 7.7 12.1 0.13 11.6 4.9 2.3 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 EKX38924.1 - 3.9 7.3 7.0 1.4 8.7 1.9 2.8 1 1 2 3 3 3 0 Septum formation initiator Fcf1 PF04900.12 EKX38925.1 - 1.7e-23 82.9 0.3 2.9e-23 82.1 0.3 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 EKX38925.1 - 0.0007 19.9 0.0 0.0013 19.1 0.0 1.4 1 1 0 1 1 1 1 PIN like domain Mito_fiss_reg PF05308.11 EKX38925.1 - 0.45 10.6 7.4 0.72 9.9 7.4 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator NicO PF03824.16 EKX38925.1 - 1.6 8.0 8.9 2 7.7 8.9 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein SelP_N PF04592.14 EKX38925.1 - 2.7 7.3 30.3 5.2 6.4 30.3 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region AGTRAP PF06396.11 EKX38926.1 - 3e-05 23.8 1.2 5.7e-05 22.9 1.2 1.5 1 1 0 1 1 1 1 Angiotensin II, type I receptor-associated protein (AGTRAP) DUF5090 PF17009.5 EKX38926.1 - 0.098 12.6 0.2 0.098 12.6 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) Cellulase PF00150.18 EKX38927.1 - 2.2e-14 53.6 2.3 3e-14 53.1 2.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) W2 PF02020.18 EKX38927.1 - 0.12 12.6 0.0 0.34 11.1 0.0 1.8 1 0 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon Ribosomal_S21 PF01165.20 EKX38928.1 - 7.7e-15 54.4 9.0 7.7e-15 54.4 9.0 1.6 1 1 1 2 2 2 1 Ribosomal protein S21 Condensation PF00668.20 EKX38929.1 - 4.9e-07 28.8 0.0 2.6e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Condensation domain Transferase PF02458.15 EKX38929.1 - 0.00037 19.3 0.0 0.097 11.3 0.0 2.4 2 0 0 2 2 2 2 Transferase family CBM_20 PF00686.19 EKX38931.1 - 9.5e-47 156.9 0.2 7.1e-25 86.7 0.0 2.4 2 0 0 2 2 2 2 Starch binding domain TMF_TATA_bd PF12325.8 EKX38931.1 - 0.0014 18.8 7.7 0.0035 17.6 7.7 1.6 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding CBM53 PF16760.5 EKX38931.1 - 0.0018 18.8 0.1 0.058 14.0 0.0 2.4 2 0 0 2 2 2 1 Starch/carbohydrate-binding module (family 53) CBM_48 PF02922.18 EKX38931.1 - 0.02 15.2 0.2 0.47 10.8 0.0 2.3 2 0 0 2 2 2 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DUF3450 PF11932.8 EKX38931.1 - 0.039 13.2 4.9 0.081 12.2 4.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) L_lactis_ph-MCP PF06673.11 EKX38931.1 - 0.068 12.2 2.4 0.1 11.6 2.4 1.2 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein Miga PF10265.9 EKX38931.1 - 0.084 11.8 1.4 0.12 11.4 1.4 1.2 1 0 0 1 1 1 0 Mitoguardin TFA2_Winged_2 PF18121.1 EKX38931.1 - 0.11 12.2 0.1 0.29 10.8 0.1 1.7 1 0 0 1 1 1 0 TFA2 Winged helix domain 2 Leu_zip PF15294.6 EKX38931.1 - 0.16 11.5 8.3 0.25 10.8 8.3 1.2 1 0 0 1 1 1 0 Leucine zipper FliT PF05400.13 EKX38931.1 - 0.37 11.6 9.4 16 6.4 0.1 2.6 1 1 1 2 2 2 0 Flagellar protein FliT TMPIT PF07851.13 EKX38931.1 - 0.39 9.9 4.7 0.64 9.2 4.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein Fmp27_WPPW PF10359.9 EKX38931.1 - 0.49 9.2 5.1 0.74 8.6 5.1 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain UPF0242 PF06785.11 EKX38931.1 - 0.7 10.0 5.4 1.5 8.9 5.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CHDCT2 PF08074.11 EKX38931.1 - 1 9.5 4.0 0.7 10.0 0.9 2.2 2 1 1 3 3 3 0 CHDCT2 (NUC038) domain SKA2 PF16740.5 EKX38931.1 - 2.7 7.8 7.8 7.4 6.4 4.5 2.4 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 ZapB PF06005.12 EKX38931.1 - 3.1 8.3 11.3 6.9 7.2 6.4 2.5 2 0 0 2 2 2 0 Cell division protein ZapB Sec34 PF04136.15 EKX38931.1 - 3.8 7.4 5.8 2.1 8.2 1.3 2.3 2 1 1 3 3 2 0 Sec34-like family Nsp1_C PF05064.13 EKX38931.1 - 4.1 7.2 7.6 1.5 8.6 4.1 2.0 2 0 0 2 2 2 0 Nsp1-like C-terminal region DUF948 PF06103.11 EKX38931.1 - 5.1 7.4 5.3 4.1 7.7 0.6 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) CCDC-167 PF15188.6 EKX38931.1 - 8.4 6.8 10.5 13 6.2 0.0 3.0 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 BLOC1_2 PF10046.9 EKX38931.1 - 9.6 6.6 10.1 1.4 9.3 3.6 2.8 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DnaJ PF00226.31 EKX38932.1 - 1.8e-24 85.6 0.2 1.8e-24 85.6 0.2 1.8 2 0 0 2 2 2 1 DnaJ domain Mt_ATP-synt_B PF05405.14 EKX38932.1 - 0.26 10.9 0.5 0.44 10.2 0.5 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) RRM_1 PF00076.22 EKX38933.1 - 1.1e-25 89.2 0.0 4.8e-12 45.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EKX38933.1 - 5.6e-05 23.1 0.0 0.00042 20.3 0.0 1.9 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 EKX38933.1 - 0.00029 20.8 0.0 0.13 12.3 0.0 2.2 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EKX38933.1 - 0.03 14.4 0.0 0.63 10.2 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif PHM7_cyt PF14703.6 EKX38933.1 - 0.22 11.7 0.0 24 5.1 0.0 2.3 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF1615 PF07759.12 EKX38934.1 - 0.052 12.8 0.1 0.069 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1615) PX PF00787.24 EKX38936.1 - 0.022 14.7 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 PX domain Rad60-SLD PF11976.8 EKX38936.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like 17kDa_Anti_2 PF16998.5 EKX38936.1 - 0.11 12.5 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 17 kDa outer membrane surface antigen EF-hand_6 PF13405.6 EKX38938.1 - 5.8e-16 57.0 0.8 6.8e-08 31.8 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EKX38938.1 - 1.6e-15 57.3 0.4 2.6e-15 56.6 0.4 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX38938.1 - 8e-15 53.2 0.5 4.9e-07 28.9 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX38938.1 - 2.1e-12 46.7 0.9 4.3e-08 32.9 0.3 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX38938.1 - 5.6e-10 38.2 1.0 0.00054 19.3 0.1 2.4 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 EKX38938.1 - 0.008 16.5 0.3 0.085 13.2 0.1 2.0 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 EKX38938.1 - 0.014 16.3 0.0 0.016 16.0 0.0 1.1 1 0 0 1 1 1 0 EF-hand domain EF-hand_9 PF14658.6 EKX38938.1 - 0.032 14.5 0.0 0.1 12.9 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain EF-hand_10 PF14788.6 EKX38938.1 - 0.13 12.2 2.4 0.26 11.2 0.1 2.3 1 1 2 3 3 3 0 EF hand Heme_oxygenase PF01126.20 EKX38939.1 - 3.8e-22 79.1 0.2 5.2e-22 78.6 0.2 1.1 1 0 0 1 1 1 1 Heme oxygenase TENA_THI-4 PF03070.16 EKX38939.1 - 0.031 14.1 0.3 0.052 13.3 0.3 1.4 1 0 0 1 1 1 0 TENA/THI-4/PQQC family DUF3974 PF13120.6 EKX38939.1 - 0.1 12.7 0.0 0.27 11.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3974) Prok_Ub PF14454.6 EKX38940.1 - 0.019 14.6 0.0 0.045 13.4 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic Ubiquitin Kelch_1 PF01344.25 EKX38942.1 - 2.7e-10 39.6 0.7 0.00079 19.0 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 EKX38942.1 - 0.00065 19.9 0.3 0.086 13.2 0.1 3.4 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 EKX38942.1 - 0.0068 16.3 0.1 5.9 7.0 0.0 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 EKX38942.1 - 0.041 14.2 12.0 0.11 12.8 0.1 3.9 4 0 0 4 4 4 0 Galactose oxidase, central domain DUF1952 PF09189.10 EKX38942.1 - 0.042 13.7 0.2 0.3 10.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1952) Kelch_5 PF13854.6 EKX38942.1 - 0.065 13.2 0.3 0.39 10.7 0.0 2.4 2 0 0 2 2 2 0 Kelch motif Apt1 PF10351.9 EKX38942.1 - 6 5.6 11.0 0.14 11.0 4.0 1.8 2 0 0 2 2 2 0 Golgi-body localisation protein domain TIR_2 PF13676.6 EKX38943.1 - 0.025 15.2 0.3 0.25 12.0 0.0 2.9 2 0 0 2 2 2 0 TIR domain RWP-RK PF02042.15 EKX38944.1 - 2.1e-20 72.4 0.0 3.2e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_Mga PF08280.11 EKX38944.1 - 0.032 14.3 0.0 0.052 13.6 0.0 1.3 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain IBR PF01485.21 EKX38945.1 - 6e-08 32.8 10.9 6e-08 32.8 10.9 4.7 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EKX38945.1 - 0.0011 19.2 6.4 0.0011 19.2 6.4 4.6 4 0 0 4 4 4 1 Ring finger domain zf-HC5HC2H PF13771.6 EKX38945.1 - 2 8.7 27.8 0.4 11.0 3.5 3.8 3 0 0 3 3 3 0 PHD-like zinc-binding domain IBR PF01485.21 EKX38946.1 - 5.5e-08 32.9 10.9 5.5e-08 32.9 10.9 4.5 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain IBR PF01485.21 EKX38947.1 - 8.5e-08 32.3 10.9 8.5e-08 32.3 10.9 4.6 2 1 1 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EKX38947.1 - 0.00086 19.6 6.1 0.00086 19.6 6.1 4.7 4 0 0 4 4 4 1 Ring finger domain zf-HC5HC2H PF13771.6 EKX38947.1 - 2.2 8.6 26.5 0.56 10.5 2.8 3.9 3 0 0 3 3 3 0 PHD-like zinc-binding domain IBR PF01485.21 EKX38948.1 - 6.1e-08 32.8 10.9 6.1e-08 32.8 10.9 4.7 2 1 1 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EKX38948.1 - 0.0011 19.2 6.4 0.0011 19.2 6.4 4.7 4 0 0 4 4 4 1 Ring finger domain zf-HC5HC2H PF13771.6 EKX38948.1 - 6.6 7.1 27.8 0.77 10.1 2.7 3.8 3 0 0 3 3 3 0 PHD-like zinc-binding domain IBR PF01485.21 EKX38949.1 - 6e-08 32.8 10.9 6e-08 32.8 10.9 4.7 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EKX38949.1 - 0.0011 19.2 6.4 0.0011 19.2 6.4 4.6 4 0 0 4 4 4 1 Ring finger domain zf-HC5HC2H PF13771.6 EKX38949.1 - 7.1 7.0 27.4 1.1 9.5 2.8 3.8 3 0 0 3 3 3 0 PHD-like zinc-binding domain IBR PF01485.21 EKX38950.1 - 6.5e-08 32.7 10.9 6.5e-08 32.7 10.9 4.7 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EKX38950.1 - 0.00086 19.6 6.1 0.00086 19.6 6.1 4.7 4 0 0 4 4 4 1 Ring finger domain zf-HC5HC2H PF13771.6 EKX38950.1 - 5.1 7.4 27.7 0.76 10.1 3.7 3.8 3 0 0 3 3 3 0 PHD-like zinc-binding domain zf-C3HC4_2 PF13923.6 EKX38950.1 - 9.1 6.2 35.0 0.062 13.2 4.4 5.2 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) PDZ_6 PF17820.1 EKX38951.1 - 3.3e-09 36.4 0.5 5.8e-09 35.7 0.5 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX38951.1 - 8.9e-09 35.6 0.2 1.2e-08 35.2 0.2 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX38951.1 - 0.0007 19.9 0.1 0.00095 19.4 0.1 1.2 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX38951.1 - 0.0054 16.7 0.2 0.0085 16.0 0.2 1.3 1 0 0 1 1 1 1 Tricorn protease PDZ domain RNA_POL_M_15KD PF02150.16 EKX38952.1 - 3e-06 27.0 5.3 6.4e-06 25.9 1.2 2.6 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit DUF2947 PF11163.8 EKX38952.1 - 0.075 12.9 1.8 0.37 10.6 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2947) TFIIS_C PF01096.18 EKX38952.1 - 1.4 8.8 18.0 0.34 10.8 7.9 3.8 3 1 0 3 3 3 0 Transcription factor S-II (TFIIS) Zn_ribbon_recom PF13408.6 EKX38952.1 - 9.1 6.9 11.0 0.44 11.1 0.4 2.8 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain gpD PF02925.16 EKX38953.1 - 0.011 15.7 0.1 0.02 14.9 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage scaffolding protein D zf-C3HC4_2 PF13923.6 EKX38953.1 - 4 7.4 5.6 1.1 9.2 1.6 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 EKX38954.1 - 7.7e-17 61.2 15.5 1.5e-16 60.3 15.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger Cpn60_TCP1 PF00118.24 EKX38954.1 - 8.3e-09 34.6 0.2 2.3e-08 33.2 0.0 1.6 2 0 0 2 2 2 1 TCP-1/cpn60 chaperonin family PH PF00169.29 EKX38954.1 - 1.4e-06 28.8 1.3 1.4e-05 25.6 0.1 2.8 3 0 0 3 3 3 1 PH domain FYVE_2 PF02318.16 EKX38954.1 - 0.012 15.8 8.0 0.012 15.8 8.0 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger PhnA_Zn_Ribbon PF08274.12 EKX38954.1 - 0.017 15.1 1.1 0.23 11.5 1.1 2.4 1 1 0 1 1 1 0 PhnA Zinc-Ribbon PH_11 PF15413.6 EKX38954.1 - 0.22 12.0 2.2 4.9 7.6 0.3 3.1 2 1 1 3 3 3 0 Pleckstrin homology domain zf-UBP PF02148.19 EKX38954.1 - 1.8 8.9 10.1 6 7.3 10.1 1.9 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein DZR PF12773.7 EKX38954.1 - 8.2 6.5 11.5 24 5.0 1.7 2.4 1 1 1 2 2 2 0 Double zinc ribbon FRG PF08867.11 EKX38955.1 - 1.3e-23 83.8 0.0 2.5e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 FRG domain CCDC92 PF14916.6 EKX38956.1 - 0.0086 15.8 0.3 0.017 14.9 0.3 1.5 1 0 0 1 1 1 1 Coiled-coil domain of unknown function CHAT PF12770.7 EKX38957.1 - 1.6e-37 129.5 0.0 2.1e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 CHAT domain Phage_Nu1 PF07471.12 EKX38957.1 - 0.043 13.6 0.1 16 5.3 0.1 2.7 2 1 0 2 2 2 0 Phage DNA packaging protein Nu1 Pinin_SDK_memA PF04696.13 EKX38958.1 - 0.018 15.1 0.5 0.026 14.6 0.5 1.3 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Pkinase PF00069.25 EKX38959.1 - 3.6e-46 157.7 0.0 4.4e-46 157.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX38959.1 - 2.5e-41 141.7 0.0 2.8e-41 141.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX38959.1 - 0.0037 17.2 0.0 0.098 12.6 0.0 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EKX38959.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 EKX38959.1 - 0.14 10.9 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 EKX38960.1 - 1.6e-46 158.8 0.0 1.9e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX38960.1 - 1.9e-45 155.2 0.0 2.2e-45 155.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX38960.1 - 0.0059 16.5 0.0 0.16 11.9 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX38960.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Thioredoxin PF00085.20 EKX38962.1 - 5.1e-37 126.0 1.4 1.5e-26 92.4 0.0 5.1 4 1 0 4 4 4 4 Thioredoxin Thioredoxin_6 PF13848.6 EKX38962.1 - 6.6e-13 49.0 0.4 0.0041 17.1 0.0 5.0 5 1 0 5 5 5 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EKX38962.1 - 4.8e-09 36.6 0.4 0.0072 16.8 0.1 3.6 3 0 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EKX38962.1 - 3.5e-07 29.9 0.5 0.0025 17.2 0.0 3.4 4 0 0 4 4 4 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EKX38962.1 - 8.6e-07 29.2 0.1 0.26 11.6 0.0 4.4 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_3 PF13192.6 EKX38962.1 - 0.0039 17.2 0.3 1.9 8.6 0.0 2.9 2 0 0 2 2 2 2 Thioredoxin domain TraF PF13728.6 EKX38962.1 - 0.062 13.1 0.0 0.062 13.1 0.0 3.7 4 0 0 4 4 4 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 EKX38962.1 - 0.44 10.3 0.0 0.44 10.3 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin CPSF100_C PF13299.6 EKX38962.1 - 9.8 6.3 13.6 13 6.0 0.5 2.6 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Ad_cyc_g-alpha PF08509.11 EKX38966.1 - 0.094 12.5 0.6 0.15 11.8 0.6 1.3 1 0 0 1 1 1 0 Adenylate cyclase G-alpha binding domain LRR_8 PF13855.6 EKX38967.1 - 2.4e-28 97.6 33.2 2.3e-08 33.7 4.3 6.1 3 2 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 EKX38967.1 - 2.2e-23 82.0 38.3 0.00043 20.6 4.4 6.9 3 2 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX38967.1 - 0.034 14.1 3.1 0.76 9.7 1.4 2.3 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 EKX38967.1 - 0.075 13.1 25.0 0.21 11.7 0.1 7.0 7 0 0 7 7 7 0 Leucine Rich repeat AnfO_nitrog PF09582.10 EKX38967.1 - 0.28 10.5 0.8 12 5.1 0.1 2.6 3 0 0 3 3 3 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) LEDGF PF11467.8 EKX38967.1 - 0.28 10.8 4.2 1.6 8.3 0.1 3.1 2 1 1 3 3 3 0 Lens epithelium-derived growth factor (LEDGF) RdRP_3 PF00998.23 EKX38968.1 - 0.018 13.8 1.4 0.031 13.0 1.4 1.3 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase Utp8 PF10395.9 EKX38968.1 - 0.085 11.4 0.0 0.16 10.5 0.0 1.4 1 0 0 1 1 1 0 Utp8 family BRE1 PF08647.11 EKX38968.1 - 4.6 7.4 9.1 13 5.9 0.7 3.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase HemY_N PF07219.13 EKX38968.1 - 7.1 6.9 10.2 8.1 6.7 8.4 2.0 2 0 0 2 2 2 0 HemY protein N-terminus Pkinase PF00069.25 EKX38970.1 - 7.9e-51 172.9 0.0 9.3e-51 172.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX38970.1 - 3.1e-37 128.3 0.0 3.7e-37 128.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX38970.1 - 2e-07 30.6 0.0 2.8e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like CHASE9 PF17153.4 EKX38970.1 - 0.03 14.5 0.0 0.057 13.6 0.0 1.4 1 0 0 1 1 1 0 Periplasmic sensor domain, extracellular Pkinase_fungal PF17667.1 EKX38970.1 - 0.033 13.0 0.1 0.057 12.2 0.1 1.4 1 1 0 1 1 1 0 Fungal protein kinase DNA_pol_A_exo1 PF01612.20 EKX38971.1 - 2.8e-20 72.8 0.0 5.9e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease Polyketide_cyc PF03364.20 EKX38972.1 - 0.00011 22.4 0.0 0.00018 21.7 0.0 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport TPR_2 PF07719.17 EKX38973.1 - 4e-15 54.6 1.0 1.3e-05 24.9 0.0 4.5 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX38973.1 - 5.5e-15 54.5 0.3 1.6e-06 27.6 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX38973.1 - 3.1e-12 45.7 0.0 7.1e-05 22.7 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX38973.1 - 2.5e-11 42.8 0.0 0.00016 21.4 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX38973.1 - 5.8e-09 35.5 0.3 0.017 15.0 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX38973.1 - 7.5e-09 35.7 0.0 0.081 13.6 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX38973.1 - 2e-08 34.1 0.0 0.0016 18.7 0.0 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX38973.1 - 5e-08 33.1 1.6 0.046 14.0 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX38973.1 - 6.8e-08 32.7 0.4 0.18 12.7 0.0 4.2 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX38973.1 - 1.4e-06 28.7 0.0 0.00048 20.6 0.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX38973.1 - 3.8e-06 27.5 0.0 0.068 13.8 0.0 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX38973.1 - 0.00082 19.0 0.0 0.045 13.4 0.0 3.0 2 1 1 3 3 3 1 TPR repeat ANAPC3 PF12895.7 EKX38973.1 - 0.00094 19.4 0.1 0.11 12.7 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 EKX38973.1 - 0.048 13.7 0.0 17 5.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 EKX38973.1 - 0.068 13.8 0.0 5.4 8.0 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPPII_N PF12583.8 EKX38973.1 - 0.074 13.6 1.5 0.41 11.2 0.0 2.6 3 0 0 3 3 3 0 Tripeptidyl peptidase II N terminal KxDL PF10241.9 EKX38973.1 - 0.082 13.2 0.7 0.55 10.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein TPR_9 PF13371.6 EKX38973.1 - 0.093 12.9 0.0 0.87 9.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.20 EKX38973.1 - 1.5 9.2 4.2 84 3.7 0.1 4.1 4 0 0 4 4 4 0 PPR repeat DUF1415 PF07209.12 EKX38974.1 - 1.8e-53 180.8 0.0 2e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1415) TPT PF03151.16 EKX38975.1 - 3.6e-13 49.5 15.7 5.2e-13 49.0 15.7 1.3 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EKX38975.1 - 5.9e-09 36.2 28.2 7.8e-05 22.9 6.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family LapA_dom PF06305.11 EKX38975.1 - 0.088 12.6 3.7 2.3 8.1 0.4 3.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Lig_chan PF00060.26 EKX38976.1 - 6.5e-11 42.3 0.0 2.7e-10 40.3 0.0 1.8 1 1 1 2 2 2 1 Ligand-gated ion channel TNFR_c6 PF00020.18 EKX38976.1 - 0.00073 19.9 62.2 0.023 15.1 9.1 6.4 4 2 3 7 7 7 4 TNFR/NGFR cysteine-rich region SBP_bac_3 PF00497.20 EKX38976.1 - 0.003 17.0 0.0 0.11 11.9 0.0 2.3 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 RIC3 PF15361.6 EKX38976.1 - 0.049 14.0 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Flavi_NS4B PF01349.17 EKX38976.1 - 0.084 12.3 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4B PAXNEB PF05625.11 EKX38976.1 - 0.095 11.8 0.4 0.14 11.2 0.4 1.1 1 0 0 1 1 1 0 PAXNEB protein Lig_chan-Glu_bd PF10613.9 EKX38976.1 - 0.11 12.7 0.0 17 5.6 0.0 2.3 2 0 0 2 2 2 0 Ligated ion channel L-glutamate- and glycine-binding site LRR_6 PF13516.6 EKX38977.1 - 3e-07 30.0 0.5 0.0025 17.7 0.0 2.4 2 0 0 2 2 2 2 Leucine Rich repeat A_deamin PF02137.18 EKX38979.1 - 6.6e-26 91.5 0.0 1.1e-25 90.8 0.0 1.4 2 0 0 2 2 2 1 Adenosine-deaminase (editase) domain CHAT PF12770.7 EKX38980.1 - 0.0013 18.2 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 CHAT domain DUF3464 PF11947.8 EKX38980.1 - 0.015 15.0 7.3 0.93 9.2 6.5 2.4 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DUF2694 PF10904.8 EKX38980.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2694) OAD_gamma PF04277.13 EKX38980.1 - 0.75 10.4 10.0 16 6.1 8.0 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Eapp_C PF10238.9 EKX38980.1 - 0.92 9.6 7.9 0.81 9.8 4.3 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein SR-25 PF10500.9 EKX38980.1 - 1.2 8.7 27.5 0.31 10.6 23.7 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Casc1 PF12366.8 EKX38980.1 - 7.6 6.0 9.8 2.2 7.7 6.2 1.9 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 MAS20 PF02064.15 EKX38980.1 - 9.6 6.3 11.7 17 5.5 9.0 2.3 2 0 0 2 2 2 0 MAS20 protein import receptor UPF0172 PF03665.13 EKX38982.1 - 3.4e-48 164.2 0.3 3.8e-48 164.1 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.21 EKX38982.1 - 0.00024 21.1 0.0 0.00086 19.3 0.0 2.0 1 1 1 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Beta_helix PF13229.6 EKX38983.1 - 0.00032 20.6 0.0 0.0007 19.5 0.0 1.5 1 0 0 1 1 1 1 Right handed beta helix region Adeno_E1B_55K PF01696.17 EKX38983.1 - 0.0063 15.3 3.0 0.0063 15.3 3.0 1.6 2 0 0 2 2 2 1 Adenovirus EB1 55K protein / large t-antigen Pentapeptide_4 PF13599.6 EKX38983.1 - 0.058 13.6 1.3 0.58 10.4 1.3 2.4 1 1 1 2 2 2 0 Pentapeptide repeats (9 copies) Synaptonemal_3 PF15191.6 EKX38984.1 - 0.22 11.3 4.5 0.64 9.8 4.5 1.8 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 Jnk-SapK_ap_N PF09744.9 EKX38984.1 - 0.77 10.0 18.3 2.1 8.5 18.3 1.8 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Pyr_redox_2 PF07992.14 EKX38985.1 - 8.7e-21 74.4 0.0 3.4e-20 72.5 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EKX38985.1 - 4.2e-15 56.0 0.0 1.9e-14 53.9 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EKX38985.1 - 5e-08 33.4 0.5 2.5e-07 31.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EKX38985.1 - 1.3e-05 24.8 3.1 2.1e-05 24.1 3.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EKX38985.1 - 0.013 14.8 0.8 0.7 9.1 0.0 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EKX38985.1 - 0.017 14.2 1.8 0.084 11.9 0.5 2.3 2 1 1 3 3 3 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EKX38985.1 - 0.029 13.5 3.0 0.029 13.4 1.1 2.1 3 0 0 3 3 3 0 FAD binding domain ThiF PF00899.21 EKX38985.1 - 0.17 11.2 0.0 0.34 10.2 0.0 1.5 1 0 0 1 1 1 0 ThiF family HI0933_like PF03486.14 EKX38985.1 - 0.27 9.9 0.5 1.8 7.2 0.6 2.2 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 EKX38985.1 - 0.83 8.9 6.2 0.75 9.0 3.6 2.0 2 0 0 2 2 2 0 Thi4 family DAHP_synth_1 PF00793.20 EKX38986.1 - 1.4e-101 339.0 0.0 1.7e-101 338.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF1186 PF06685.11 EKX38988.1 - 0.23 10.8 0.0 0.39 10.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1186) Glyco_hydro_31 PF01055.26 EKX38993.1 - 5.3e-36 124.8 0.0 9.2e-22 77.8 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 31 EGF_3 PF12947.7 EKX38993.1 - 7.7e-19 67.6 31.2 1.1e-09 38.4 14.3 3.7 3 0 0 3 3 3 2 EGF domain NtCtMGAM_N PF16863.5 EKX38993.1 - 3.4e-17 62.7 0.0 1.1e-16 61.1 0.0 1.9 2 0 0 2 2 2 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase EGF_CA PF07645.15 EKX38993.1 - 1.8e-12 47.2 36.7 1.5e-10 41.1 10.9 4.6 3 1 0 3 3 3 2 Calcium-binding EGF domain Trefoil PF00088.18 EKX38993.1 - 1.5e-07 31.2 9.3 3.5e-07 30.0 9.3 1.7 1 0 0 1 1 1 1 Trefoil (P-type) domain EGF PF00008.27 EKX38993.1 - 0.00058 20.1 8.4 0.00058 20.1 8.4 5.0 5 0 0 5 5 5 2 EGF-like domain cEGF PF12662.7 EKX38993.1 - 0.00078 19.3 13.4 0.044 13.7 1.0 2.8 2 0 0 2 2 2 2 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 EKX38993.1 - 0.0036 17.3 6.9 0.0036 17.3 6.9 3.4 3 1 0 3 3 3 2 MSP1 EGF domain 1 TIR_2 PF13676.6 EKX38994.1 - 5.3e-07 30.2 0.5 0.027 15.1 0.0 3.4 3 0 0 3 3 3 2 TIR domain DUF4709 PF15821.5 EKX38994.1 - 0.16 12.2 8.3 0.045 14.0 3.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) TIR PF01582.20 EKX38994.1 - 0.74 9.6 13.3 1.4 8.7 0.4 3.9 4 1 0 4 4 4 0 TIR domain 4HB_MCP_1 PF12729.7 EKX38995.1 - 0.021 14.4 0.2 0.028 14.0 0.2 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction BOFC_N PF08977.10 EKX38996.1 - 0.2 11.7 1.2 1.5 8.8 0.1 2.4 2 0 0 2 2 2 0 Bypass of Forespore C, N terminal Peptidase_C69 PF03577.15 EKX38998.1 - 1.7e-10 40.4 0.0 2.5e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C69 AAT PF03417.16 EKX38998.1 - 0.0025 17.6 0.0 0.0033 17.1 0.0 1.2 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Cullin PF00888.22 EKX38999.1 - 9.6e-198 658.7 8.6 1.1e-197 658.4 8.6 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EKX38999.1 - 1.4e-23 82.7 1.1 4.1e-22 78.0 0.3 3.2 3 0 0 3 3 3 1 Cullin protein neddylation domain Cas_Cas5d PF09704.10 EKX38999.1 - 0.096 12.6 0.0 0.28 11.0 0.0 1.7 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas5) Ribosomal_L6e PF01159.19 EKX38999.1 - 2.4 8.7 5.6 1.1 9.8 1.3 2.7 2 0 0 2 2 2 0 Ribosomal protein L6e 2-oxoacid_dh PF00198.23 EKX39000.1 - 0.036 13.5 0.2 0.051 13.0 0.2 1.1 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Herpes_BTRF1 PF04682.12 EKX39000.1 - 0.084 12.2 0.1 0.12 11.7 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus BTRF1 protein conserved region MTBP_C PF14920.6 EKX39000.1 - 0.34 10.6 5.1 0.48 10.1 5.1 1.1 1 0 0 1 1 1 0 MDM2-binding His_Phos_1 PF00300.22 EKX39002.1 - 8.4e-41 139.8 0.0 9.3e-41 139.7 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ERM PF00769.19 EKX39003.1 - 0.033 14.0 1.9 0.033 14.0 1.9 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family YabA PF06156.13 EKX39003.1 - 0.092 13.4 3.6 0.078 13.6 2.0 1.7 1 1 1 2 2 2 0 Initiation control protein YabA DnaJ PF00226.31 EKX39004.1 - 2.7e-19 69.0 2.1 2e-18 66.2 0.2 2.8 2 1 0 2 2 2 1 DnaJ domain Sid-5 PF17204.3 EKX39004.1 - 0.43 10.8 0.1 0.43 10.8 0.1 1.9 2 0 0 2 2 2 0 Sid-5 family Alpha_adaptinC2 PF02883.20 EKX39005.1 - 6.2e-25 87.7 0.1 7.8e-25 87.3 0.1 1.1 1 0 0 1 1 1 1 Adaptin C-terminal domain HNOBA PF07701.14 EKX39007.1 - 1.1 8.7 9.8 4.6 6.6 3.3 2.5 2 0 0 2 2 2 0 Heme NO binding associated NPV_P10 PF05531.12 EKX39007.1 - 1.3 9.6 4.8 5.1 7.6 0.5 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Cupin_8 PF13621.6 EKX39010.1 - 8.2e-25 88.0 0.0 1.3e-24 87.3 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EKX39010.1 - 7.9e-18 65.0 0.0 1.4e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EKX39010.1 - 0.0017 18.0 0.1 0.0074 16.0 0.0 2.0 2 0 0 2 2 2 1 Cupin domain Cupin_4 PF08007.12 EKX39010.1 - 0.0046 16.5 0.1 0.02 14.4 0.1 2.1 1 1 0 1 1 1 1 Cupin superfamily protein GPI PF06560.11 EKX39010.1 - 0.17 11.2 0.2 0.8 8.9 0.0 1.9 2 0 0 2 2 2 0 Glucose-6-phosphate isomerase (GPI) WD40 PF00400.32 EKX39012.1 - 3.5e-10 40.3 5.4 0.00023 21.9 0.2 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX39012.1 - 0.00087 19.5 0.0 0.0025 18.0 0.0 1.7 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Tub PF01167.18 EKX39013.1 - 2.8e-46 158.3 0.1 3e-46 158.1 0.1 1.0 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.8 EKX39013.1 - 0.0068 16.0 0.3 0.011 15.3 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3527) Tub PF01167.18 EKX39014.1 - 6.1e-13 49.1 0.1 1.1e-12 48.2 0.1 1.3 1 0 0 1 1 1 1 Tub family Sporozoite_P67 PF05642.11 EKX39014.1 - 0.029 12.5 1.1 0.039 12.0 1.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3246 PF11596.8 EKX39014.1 - 4.6 6.6 6.4 21 4.4 6.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3246) DUF3668 PF12416.8 EKX39015.1 - 0.1 12.4 0.2 0.21 11.3 0.2 1.5 2 0 0 2 2 2 0 Cep120 protein NAD_binding_9 PF13454.6 EKX39015.1 - 0.18 11.8 0.0 24 4.9 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Guanylate_cyc_2 PF09778.9 EKX39016.1 - 7.5e-49 166.0 0.1 1e-48 165.5 0.1 1.1 1 0 0 1 1 1 1 Guanylylate cyclase Peptidase_C39 PF03412.15 EKX39016.1 - 0.0051 16.6 0.0 2.4 7.9 0.0 2.4 2 1 0 2 2 2 2 Peptidase C39 family Peptidase_C39_2 PF13529.6 EKX39016.1 - 0.023 15.3 0.4 0.1 13.2 0.4 2.0 1 1 0 1 1 1 0 Peptidase_C39 like family Ank_2 PF12796.7 EKX39017.1 - 1.8e-08 34.8 0.0 0.00086 19.9 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX39017.1 - 6e-06 26.7 0.1 0.027 15.1 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Pilin_PilA PF14245.6 EKX39017.1 - 0.00036 20.5 0.0 0.025 14.6 0.0 2.2 2 0 0 2 2 2 1 Type IV pilin PilA Ank_5 PF13857.6 EKX39017.1 - 0.00094 19.4 0.0 0.24 11.8 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX39017.1 - 0.0012 19.1 0.1 1 10.2 0.0 3.1 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 EKX39017.1 - 0.008 16.6 0.1 0.024 15.1 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeat AMP-binding PF00501.28 EKX39018.1 - 1e-84 284.6 0.1 1.2e-84 284.4 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EKX39018.1 - 0.0017 19.3 0.9 0.01 16.8 0.1 2.7 4 0 0 4 4 4 1 AMP-binding enzyme C-terminal domain TPR_1 PF00515.28 EKX39019.1 - 1.4e-14 53.2 0.1 5.9e-08 32.2 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX39019.1 - 4.6e-12 45.1 0.5 0.00011 22.0 0.0 2.3 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX39019.1 - 4.2e-11 42.4 0.5 2.9e-06 26.8 0.1 2.1 1 1 1 2 2 2 2 TPR repeat TPR_17 PF13431.6 EKX39019.1 - 1.2e-10 41.0 1.1 1.7e-05 24.9 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX39019.1 - 2.3e-09 36.7 1.0 8.9e-06 25.5 0.0 2.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX39019.1 - 5.8e-08 33.1 0.0 7.4e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX39019.1 - 1.4e-07 31.7 0.9 0.0032 17.7 0.1 2.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX39019.1 - 2.1e-06 28.3 0.0 3.2e-06 27.7 0.0 1.3 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX39019.1 - 5.7e-06 26.7 0.0 0.088 13.7 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX39019.1 - 1.2e-05 25.0 0.1 0.072 13.1 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX39019.1 - 0.00028 21.0 0.0 0.00033 20.8 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF627 PF04781.12 EKX39019.1 - 0.0064 16.5 0.1 0.011 15.8 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF627) Fis1_TPR_C PF14853.6 EKX39019.1 - 0.008 16.2 0.6 0.099 12.7 0.1 2.2 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 EKX39019.1 - 0.014 16.0 0.8 4.6 8.1 0.0 2.4 3 0 0 3 3 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX39019.1 - 0.019 15.1 0.2 0.034 14.4 0.2 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 EKX39019.1 - 0.021 14.9 0.2 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.9 EKX39019.1 - 0.032 13.7 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 SHNi-TPR NRBF2_MIT PF17169.4 EKX39019.1 - 0.1 12.8 0.1 0.4 10.9 0.1 1.7 1 1 1 2 2 2 0 MIT domain of nuclear receptor-binding factor 2 TPR_20 PF14561.6 EKX39019.1 - 0.11 12.9 0.0 0.26 11.6 0.0 1.6 1 1 1 2 2 2 0 Tetratricopeptide repeat NIF PF03031.18 EKX39021.1 - 3.2e-48 163.4 0.0 1.1e-47 161.7 0.0 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase HAD PF12710.7 EKX39021.1 - 0.11 12.9 0.1 1.7 9.0 0.0 2.3 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase WD40 PF00400.32 EKX39022.1 - 4.5e-09 36.8 13.7 5.1e-06 27.1 0.1 5.5 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX39022.1 - 0.00033 20.9 0.1 0.21 11.9 0.0 3.7 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain ABC2_membrane PF01061.24 EKX39023.1 - 9e-33 113.5 13.9 1.2e-32 113.1 13.9 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EKX39023.1 - 7.3e-24 84.8 0.0 1.3e-23 84.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EKX39023.1 - 3e-07 29.9 6.4 4e-07 29.5 6.4 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 EKX39023.1 - 4.4e-06 26.7 0.1 0.0062 16.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EKX39023.1 - 5.7e-05 22.7 0.2 0.21 11.0 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EKX39023.1 - 0.00016 21.6 0.0 0.00033 20.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 EKX39023.1 - 0.0011 19.6 0.2 0.0041 17.6 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EKX39023.1 - 0.0019 17.9 0.5 0.0042 16.8 0.5 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 EKX39023.1 - 0.0048 16.5 0.6 0.0082 15.7 0.6 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EKX39023.1 - 0.014 15.8 0.2 0.096 13.1 0.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EKX39023.1 - 0.028 14.7 0.2 0.095 13.0 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EKX39023.1 - 0.029 14.8 0.1 0.09 13.2 0.1 1.9 2 1 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 EKX39023.1 - 0.031 14.4 0.1 0.061 13.4 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.19 EKX39023.1 - 0.045 13.3 0.2 0.08 12.5 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EKX39023.1 - 0.09 12.7 0.2 0.21 11.5 0.2 1.6 1 0 0 1 1 1 0 NACHT domain N2227 PF07942.12 EKX39023.1 - 0.16 11.1 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 N2227-like protein AAA_28 PF13521.6 EKX39023.1 - 0.19 12.0 0.5 0.4 10.9 0.5 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EKX39023.1 - 0.22 10.8 0.1 0.48 9.7 0.1 1.5 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 EKX39023.1 - 0.22 11.2 1.2 0.41 10.3 1.2 1.5 1 1 0 1 1 1 0 AAA domain AAA_13 PF13166.6 EKX39023.1 - 0.31 9.6 0.0 5.6 5.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain UPF0014 PF03649.13 EKX39024.1 - 0.52 9.6 4.6 0.23 10.8 2.2 1.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0014) ABC2_membrane PF01061.24 EKX39026.1 - 2.1e-34 118.8 11.5 3e-34 118.3 11.5 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EKX39026.1 - 2.8e-24 86.2 0.0 5.2e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EKX39026.1 - 3.9e-06 26.9 0.0 0.0058 16.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EKX39026.1 - 0.00013 21.5 0.4 0.43 10.0 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EKX39026.1 - 0.00021 21.2 0.1 0.00042 20.3 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 EKX39026.1 - 0.00089 19.8 0.1 0.0038 17.8 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EKX39026.1 - 0.0019 17.9 0.5 0.0039 16.9 0.5 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 EKX39026.1 - 0.0034 16.5 7.4 0.0072 15.5 7.4 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_25 PF13481.6 EKX39026.1 - 0.0061 16.2 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EKX39026.1 - 0.009 16.4 0.2 0.073 13.5 0.2 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX39026.1 - 0.024 15.0 0.1 0.077 13.4 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EKX39026.1 - 0.024 14.9 0.2 0.091 13.0 0.1 1.9 2 0 0 2 2 2 0 AAA domain 7TM-7TMR_HD PF07698.11 EKX39026.1 - 0.029 14.1 3.3 0.063 13.0 3.3 1.6 1 1 0 1 1 1 0 7TM receptor with intracellular HD hydrolase MMR_HSR1 PF01926.23 EKX39026.1 - 0.029 14.4 0.1 0.058 13.5 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.19 EKX39026.1 - 0.044 13.4 0.2 0.075 12.6 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EKX39026.1 - 0.085 12.8 0.2 0.2 11.6 0.2 1.6 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 EKX39026.1 - 0.16 12.2 0.4 0.35 11.1 0.4 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EKX39026.1 - 0.19 11.4 1.2 0.35 10.6 1.2 1.5 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EKX39026.1 - 0.2 10.9 0.1 0.43 9.8 0.1 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_13 PF13166.6 EKX39026.1 - 0.25 9.9 0.0 5.5 5.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Castor_Poll_mid PF06241.12 EKX39027.1 - 4.8e-16 58.6 0.0 1.5e-13 50.6 0.0 3.1 3 0 0 3 3 3 2 Castor and Pollux, part of voltage-gated ion channel SAPS PF04499.15 EKX39028.1 - 5e-28 98.2 10.5 7.9e-22 77.7 1.5 2.5 2 1 1 3 3 3 2 SIT4 phosphatase-associated protein GTP_EFTU PF00009.27 EKX39029.1 - 5e-30 104.5 0.4 7.9e-30 103.9 0.4 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EKX39029.1 - 2.9e-08 33.8 0.1 5.7e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 EKX39029.1 - 1.1e-05 25.1 1.7 0.00027 20.6 0.1 2.6 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 EKX39029.1 - 4.4e-05 23.0 0.9 0.00018 21.0 0.9 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EKX39029.1 - 0.00012 21.5 0.3 0.00024 20.5 0.3 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU_D2 PF03144.25 EKX39029.1 - 0.0031 17.9 0.5 0.057 13.8 0.5 2.7 1 1 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 EKX39029.1 - 0.0066 16.4 0.8 0.086 12.7 0.2 2.3 2 0 0 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 EKX39029.1 - 0.0072 16.1 1.6 1.9 8.2 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 EKX39029.1 - 0.034 13.9 0.2 4.8 6.9 0.0 2.5 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Arf PF00025.21 EKX39029.1 - 0.093 12.2 0.2 0.2 11.1 0.0 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family PEX11 PF05648.14 EKX39030.1 - 5.4e-15 55.5 0.2 6.4e-15 55.2 0.2 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Ycf70 PF17382.2 EKX39030.1 - 0.013 15.9 0.0 0.023 15.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized Ycf70-like TMEM208_SND2 PF05620.11 EKX39030.1 - 0.065 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Big_5 PF13205.6 EKX39031.1 - 0.044 14.5 0.5 0.09 13.5 0.5 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain WD40 PF00400.32 EKX39032.1 - 1.7e-19 69.8 6.0 3.6e-05 24.4 0.0 8.2 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX39032.1 - 2.8e-05 24.3 0.0 0.014 15.7 0.0 4.3 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain UPF0154 PF03672.13 EKX39032.1 - 0.0015 18.5 0.2 0.14 12.2 0.4 2.4 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) Frtz PF11768.8 EKX39032.1 - 0.035 12.4 0.1 0.059 11.7 0.1 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz SNF2_N PF00176.23 EKX39033.1 - 7.2e-31 107.2 0.0 1.1e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX39033.1 - 3e-14 53.3 0.5 5.3e-13 49.3 0.0 2.7 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX39033.1 - 1.8e-05 24.8 0.1 0.0021 18.1 0.0 3.6 2 2 2 4 4 4 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EKX39033.1 - 0.00046 19.5 0.9 0.0011 18.3 0.1 1.8 1 1 1 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Ank_4 PF13637.6 EKX39034.1 - 5.3e-29 100.2 0.3 7.6e-09 35.9 0.1 5.4 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX39034.1 - 6.1e-26 90.8 3.3 2.6e-08 34.3 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX39034.1 - 5.2e-21 72.5 5.6 0.00089 19.5 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EKX39034.1 - 4.4e-18 65.1 9.8 1.1e-10 41.5 0.0 4.8 5 1 0 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX39034.1 - 1.2e-17 63.5 5.3 0.0002 21.7 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat TPR_1 PF00515.28 EKX39034.1 - 7.5e-07 28.7 1.9 0.003 17.3 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat CS PF04969.16 EKX39034.1 - 4.9e-05 24.3 0.0 0.0001 23.2 0.0 1.6 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 EKX39034.1 - 0.0033 17.4 7.7 0.12 12.5 0.0 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX39034.1 - 0.11 13.1 1.1 0.41 11.3 1.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3689 PF12463.8 EKX39035.1 - 1.8e-79 267.3 6.6 3.8e-79 266.2 6.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3689) Mac PF12464.8 EKX39036.1 - 0.086 13.1 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Maltose acetyltransferase Ank_2 PF12796.7 EKX39037.1 - 4.5e-33 113.7 1.0 1.1e-15 58.0 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX39037.1 - 3.3e-29 100.6 11.6 5.6e-13 48.8 0.6 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX39037.1 - 3.1e-24 85.0 1.3 4.6e-08 33.5 0.0 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX39037.1 - 5.3e-21 72.5 0.1 1.7e-05 24.8 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EKX39037.1 - 1e-20 73.2 0.7 0.00012 22.4 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat BK_channel_a PF03493.18 EKX39038.1 - 1.1e-29 102.4 0.1 3.1e-29 101.0 0.1 1.8 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 EKX39038.1 - 5.5e-14 52.0 21.5 3.5e-13 49.3 21.5 2.0 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX39038.1 - 1.1e-12 47.7 7.2 2.7e-12 46.5 7.2 1.7 1 0 0 1 1 1 1 Ion channel C2 PF00168.30 EKX39038.1 - 9.6e-10 38.7 0.0 1.8e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain Snf7 PF03357.21 EKX39039.1 - 4.7e-29 101.2 12.7 6.2e-29 100.8 12.7 1.1 1 0 0 1 1 1 1 Snf7 Allexi_40kDa PF05549.11 EKX39039.1 - 0.86 9.1 4.1 7.7 5.9 0.3 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein Ribosomal_60s PF00428.19 EKX39039.1 - 0.92 10.1 5.8 2.3 8.9 1.8 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF2681 PF10883.8 EKX39039.1 - 8.9 6.8 10.5 44 4.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) WD40 PF00400.32 EKX39040.1 - 1.5e-11 44.7 9.1 0.00028 21.6 0.8 5.5 5 1 0 5 5 5 3 WD domain, G-beta repeat WD40_like PF17005.5 EKX39040.1 - 0.052 12.9 0.3 0.1 11.9 0.0 1.6 2 0 0 2 2 2 0 WD40-like domain PQQ_3 PF13570.6 EKX39040.1 - 0.092 13.3 1.1 1.1 9.8 0.0 2.9 3 1 1 4 4 4 0 PQQ-like domain VCBS PF13517.6 EKX39040.1 - 0.44 11.2 3.1 0.68 10.6 0.2 2.5 2 1 1 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella MBT PF02820.18 EKX39041.1 - 2.2e-05 24.7 0.0 5.2e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 mbt repeat Tudor-knot PF11717.8 EKX39041.1 - 0.025 14.5 0.1 0.069 13.0 0.1 1.7 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Methyltransf_16 PF10294.9 EKX39043.1 - 3.7e-06 26.8 0.0 4.3e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EKX39043.1 - 0.00026 20.6 0.0 0.0003 20.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.12 EKX39043.1 - 0.0088 15.6 0.0 0.0094 15.5 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase RrnaAD PF00398.20 EKX39043.1 - 0.019 14.0 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DEAD_assoc PF08494.11 EKX39043.1 - 0.028 14.2 0.5 0.039 13.8 0.5 1.1 1 0 0 1 1 1 0 DEAD/H associated PCMT PF01135.19 EKX39043.1 - 0.095 12.4 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 EKX39043.1 - 0.1 12.4 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 EKX39043.1 - 0.14 11.4 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Ank PF00023.30 EKX39044.1 - 1.3e-13 50.7 1.4 5.7e-07 29.7 0.0 2.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EKX39044.1 - 2.4e-13 50.3 2.0 1.7e-09 38.1 0.2 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX39044.1 - 6.1e-13 49.2 0.2 8.3e-13 48.7 0.2 1.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX39044.1 - 1.3e-12 46.6 0.3 3.6e-05 23.8 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EKX39044.1 - 2.9e-10 40.2 1.2 0.00011 22.4 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF1187 PF06688.11 EKX39045.1 - 0.16 12.3 0.1 0.71 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1187) DUF3339 PF11820.8 EKX39046.1 - 0.0098 16.1 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3339) Peptidase_C1 PF00112.23 EKX39047.1 - 2.3e-71 240.4 3.6 3e-71 240.0 3.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EKX39047.1 - 2.8e-15 56.5 1.4 4.9e-15 55.7 1.4 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EKX39047.1 - 3.9e-05 22.6 4.9 0.0055 15.5 0.9 2.1 2 0 0 2 2 2 2 Peptidase C1-like family DUF4486 PF14858.6 EKX39048.1 - 3.5e-50 171.0 12.1 2.9e-44 151.5 1.2 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4486) fn3 PF00041.21 EKX39048.1 - 0.0062 16.8 0.0 0.026 14.8 0.0 2.0 2 0 0 2 2 2 1 Fibronectin type III domain UCR_UQCRX_QCR9 PF05365.12 EKX39048.1 - 0.097 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like CBM9_1 PF06452.11 EKX39049.1 - 9.9e-09 35.4 1.1 1.7e-08 34.6 1.1 1.3 1 0 0 1 1 1 1 Carbohydrate family 9 binding domain-like CBM9_2 PF16011.5 EKX39049.1 - 1.7e-05 24.6 0.0 2.6e-05 24.0 0.0 1.3 1 1 0 1 1 1 1 Carbohydrate-binding family 9 Laminin_G_2 PF02210.24 EKX39049.1 - 0.12 12.9 0.3 1.2 9.7 0.1 2.4 1 1 1 2 2 2 0 Laminin G domain Beta_helix PF13229.6 EKX39050.1 - 4.9e-11 42.7 15.5 1.8e-06 27.9 6.6 2.3 1 1 1 2 2 2 2 Right handed beta helix region F5_F8_type_C PF00754.25 EKX39050.1 - 3.5e-06 27.2 0.0 9.1e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 F5/8 type C domain NosD PF05048.13 EKX39050.1 - 1.7e-05 24.3 8.3 0.00055 19.3 4.2 2.2 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) IQ PF00612.27 EKX39050.1 - 0.0005 19.6 0.6 0.0024 17.5 0.0 2.6 2 0 0 2 2 2 1 IQ calmodulin-binding motif MIB_HERC2 PF06701.13 EKX39050.1 - 0.0019 18.4 9.4 5.2 7.4 0.0 5.1 4 1 1 5 5 5 3 Mib_herc2 CitMHS PF03600.16 EKX39051.1 - 0.016 14.4 0.1 0.036 13.3 0.1 1.6 1 0 0 1 1 1 0 Citrate transporter Saf_2TM PF18303.1 EKX39051.1 - 1.2 8.7 5.9 3.5 7.2 1.2 3.3 3 1 1 4 4 4 0 SAVED-fused 2TM effector domain YtpI PF14007.6 EKX39051.1 - 6.7 6.9 6.1 2 8.6 0.1 2.8 3 0 0 3 3 3 0 YtpI-like protein TMEM189_B_dmain PF10520.9 EKX39052.1 - 1.5e-58 197.7 1.2 1.7e-58 197.5 1.2 1.0 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain FA_hydroxylase PF04116.13 EKX39052.1 - 0.00021 21.6 1.4 0.00025 21.4 1.4 1.2 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Ycf34 PF10718.9 EKX39053.1 - 1.4e-31 109.0 3.6 1.6e-31 108.8 3.6 1.0 1 0 0 1 1 1 1 Hypothetical chloroplast protein Ycf34 2_5_RNA_ligase2 PF13563.6 EKX39053.1 - 0.0094 15.9 0.0 0.01 15.7 0.0 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LRR_8 PF13855.6 EKX39054.1 - 2.9e-42 142.2 52.2 2.5e-09 36.8 1.4 9.8 5 4 4 10 10 10 9 Leucine rich repeat LRR_4 PF12799.7 EKX39054.1 - 2.8e-37 126.1 47.8 0.00031 21.1 0.9 11.2 9 2 3 12 12 12 10 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX39054.1 - 2.9e-08 33.4 22.5 0.0043 16.6 2.8 5.8 1 1 5 6 6 6 3 Leucine-rich repeat LRR_1 PF00560.33 EKX39054.1 - 1.3e-06 28.1 50.7 0.47 11.2 0.7 15.0 16 2 0 16 16 16 4 Leucine Rich Repeat EF-hand_7 PF13499.6 EKX39054.1 - 1.1e-05 25.7 0.1 3e-05 24.4 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX39054.1 - 9.7e-05 21.7 0.3 0.00045 19.6 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EKX39054.1 - 0.0001 21.9 0.6 0.00037 20.2 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 EKX39054.1 - 0.0048 16.7 0.0 0.016 15.0 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX39054.1 - 0.019 14.5 0.7 0.043 13.3 0.1 2.0 2 0 0 2 2 2 0 EF hand Ank_2 PF12796.7 EKX39055.1 - 1e-17 64.4 0.9 4.3e-09 36.8 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) TPR_12 PF13424.6 EKX39055.1 - 3.5e-09 36.8 20.7 0.18 12.1 1.2 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat Ank_3 PF13606.6 EKX39055.1 - 7.4e-09 35.2 0.3 0.0051 17.2 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EKX39055.1 - 7.8e-09 35.9 0.0 2.3e-08 34.4 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX39055.1 - 5.7e-06 26.5 0.7 0.00014 22.1 0.1 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX39055.1 - 5.5e-05 23.4 0.9 0.017 15.6 0.1 3.0 2 0 0 2 2 2 1 Ankyrin repeat TPR_1 PF00515.28 EKX39055.1 - 0.00067 19.4 5.9 8.5 6.4 0.1 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3969 PF13108.6 EKX39055.1 - 0.0076 16.3 0.3 0.031 14.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3969) TPR_2 PF07719.17 EKX39055.1 - 0.02 15.0 15.4 6 7.2 0.2 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2564 PF10819.8 EKX39055.1 - 1.1 9.7 32.2 0.064 13.6 2.1 5.5 5 1 0 5 5 5 0 Protein of unknown function (DUF2564) Ank_2 PF12796.7 EKX39056.1 - 6.6e-14 52.3 0.5 1.9e-08 34.7 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX39056.1 - 1.5e-11 44.5 1.5 1.4e-06 28.8 0.1 3.9 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX39056.1 - 3.3e-10 40.0 0.4 1.3e-06 28.5 0.1 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX39056.1 - 5.8e-10 38.5 0.8 1.6e-05 24.9 0.0 4.5 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 EKX39056.1 - 2.8e-09 37.0 3.1 3.1e-06 27.4 1.5 4.3 3 2 0 3 3 3 1 Ankyrin repeat FliT PF05400.13 EKX39056.1 - 0.041 14.7 0.2 0.11 13.3 0.1 1.8 2 0 0 2 2 2 0 Flagellar protein FliT DUF1843 PF08898.10 EKX39056.1 - 0.055 14.0 0.0 0.2 12.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Neocarzinostat PF00960.18 EKX39056.1 - 0.1 12.6 1.1 0.32 11.0 0.1 2.3 2 1 0 2 2 2 0 Neocarzinostatin family TTL PF03133.15 EKX39057.1 - 9.8e-59 198.9 0.0 1.2e-58 198.6 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EKX39057.1 - 4.4e-10 39.2 0.6 9.9e-06 25.0 0.0 3.0 2 1 0 2 2 2 2 YheC/D like ATP-grasp Cas_St_Csn2 PF16813.5 EKX39057.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein Csn2 subfamily St DUF647 PF04884.14 EKX39058.1 - 1.9e-40 139.1 1.9 2.5e-21 76.4 0.2 2.2 1 1 1 2 2 2 2 Vitamin B6 photo-protection and homoeostasis DBP10CT PF08147.12 EKX39058.1 - 0.081 13.2 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 DBP10CT (NUC160) domain PDZ_6 PF17820.1 EKX39059.1 - 1.4e-11 44.0 0.1 1.8e-11 43.7 0.1 1.2 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX39059.1 - 1.7e-07 31.5 0.0 2.1e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX39059.1 - 2.3e-06 27.8 0.0 2.8e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 PDZ domain Biotin_lipoyl_2 PF13533.6 EKX39059.1 - 0.054 13.3 0.1 0.093 12.6 0.1 1.3 1 0 0 1 1 1 0 Biotin-lipoyl like adh_short PF00106.25 EKX39060.1 - 7.9e-40 136.4 0.0 1.3e-39 135.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EKX39060.1 - 1.2e-39 136.3 0.0 1.9e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Aldolase_II PF00596.21 EKX39060.1 - 2.4e-22 79.8 0.0 6.8e-22 78.3 0.0 1.8 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain KR PF08659.10 EKX39060.1 - 2.2e-05 24.5 0.4 0.00051 20.0 0.4 2.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EKX39060.1 - 0.00069 19.1 0.0 0.0019 17.7 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EKX39060.1 - 0.011 15.6 0.1 0.052 13.4 0.0 2.0 2 0 0 2 2 2 0 NAD(P)H-binding 3Beta_HSD PF01073.19 EKX39060.1 - 0.022 13.8 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1664 PF07889.12 EKX39061.1 - 8.4e-05 22.6 2.2 0.00014 21.8 2.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 EKX39061.1 - 0.0031 17.5 6.2 0.0031 17.5 6.2 2.6 2 1 0 2 2 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.8 EKX39061.1 - 0.0037 17.2 0.4 0.0037 17.2 0.4 3.1 3 0 0 3 3 3 1 TATA element modulatory factor 1 DNA binding Nup88 PF10168.9 EKX39061.1 - 0.0044 14.9 1.9 0.0065 14.3 1.9 1.3 1 0 0 1 1 1 1 Nuclear pore component HALZ PF02183.18 EKX39061.1 - 0.0064 16.7 3.2 0.19 12.0 0.3 2.6 2 0 0 2 2 2 1 Homeobox associated leucine zipper Spc7 PF08317.11 EKX39061.1 - 0.0072 15.2 4.2 0.0072 15.2 4.2 1.6 2 0 0 2 2 1 1 Spc7 kinetochore protein TolA_bind_tri PF16331.5 EKX39061.1 - 0.013 15.5 0.5 0.052 13.6 0.1 2.0 2 0 0 2 2 2 0 TolA binding protein trimerisation APG6_N PF17675.1 EKX39061.1 - 0.024 15.2 4.5 0.024 15.2 4.5 2.2 2 0 0 2 2 1 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 EKX39061.1 - 0.024 14.9 3.8 0.024 14.9 3.8 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 GIT_CC PF16559.5 EKX39061.1 - 0.03 14.2 0.6 0.03 14.2 0.6 1.8 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2564 PF10819.8 EKX39061.1 - 0.033 14.6 1.5 0.079 13.4 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) DivIC PF04977.15 EKX39061.1 - 0.037 13.8 4.2 0.054 13.3 1.2 2.3 1 1 0 2 2 2 0 Septum formation initiator DUF2605 PF10792.9 EKX39061.1 - 0.047 13.6 0.6 0.088 12.7 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) BLOC1_2 PF10046.9 EKX39061.1 - 0.058 13.7 6.2 1.2 9.5 3.3 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_1 PF00170.21 EKX39061.1 - 0.064 13.4 1.5 0.064 13.4 1.5 2.5 3 0 0 3 3 2 0 bZIP transcription factor DUF3450 PF11932.8 EKX39061.1 - 0.1 11.9 2.6 0.18 11.1 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FlaC_arch PF05377.11 EKX39061.1 - 0.15 12.4 6.4 0.75 10.2 1.6 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 EKX39061.1 - 0.36 11.3 4.2 8 7.0 1.7 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CENP-H PF05837.12 EKX39061.1 - 0.49 10.8 10.7 14 6.1 0.2 3.1 3 0 0 3 3 3 0 Centromere protein H (CENP-H) DASH_Dam1 PF08653.10 EKX39061.1 - 1.1 9.1 4.4 12 5.8 0.4 2.5 2 0 0 2 2 2 0 DASH complex subunit Dam1 TPR_MLP1_2 PF07926.12 EKX39061.1 - 2.4 8.2 15.2 0.12 12.4 3.8 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2203 PF09969.9 EKX39061.1 - 2.6 8.8 6.3 0.43 11.3 0.5 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Syntaxin-6_N PF09177.11 EKX39061.1 - 3 8.4 9.3 2.1 9.0 0.8 2.6 2 1 1 3 3 2 0 Syntaxin 6, N-terminal DUF4611 PF15387.6 EKX39061.1 - 6.5 7.0 12.6 1.1 9.5 7.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Mod_r PF07200.13 EKX39061.1 - 8 6.6 15.4 0.078 13.1 7.7 1.5 2 0 0 2 2 1 0 Modifier of rudimentary (Mod(r)) protein Isochorismatase PF00857.20 EKX39062.1 - 2.2e-32 112.6 0.2 2.9e-32 112.2 0.2 1.1 1 0 0 1 1 1 1 Isochorismatase family Pyr_redox_2 PF07992.14 EKX39062.1 - 0.037 13.3 0.0 0.041 13.1 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Put_DNA-bind_N PF06971.13 EKX39062.1 - 0.075 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus Ni_hydr_CYTB PF01292.20 EKX39062.1 - 0.088 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 DUF1485 PF07364.12 EKX39062.1 - 0.17 11.1 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase family M81 HAD_2 PF13419.6 EKX39063.1 - 5.5e-05 23.3 0.0 0.00033 20.8 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EKX39063.1 - 0.0055 16.7 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EKX39063.1 - 0.0093 16.3 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 EKX39063.1 - 0.02 14.7 0.3 0.038 13.8 0.3 1.4 1 0 0 1 1 1 0 Acid Phosphatase Proteasome PF00227.26 EKX39065.1 - 2.1e-43 148.0 0.6 2.6e-43 147.8 0.6 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF3834 PF12916.7 EKX39065.1 - 0.0049 16.1 0.0 1.4 8.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3834) UPF0113_N PF17833.1 EKX39066.1 - 1.5e-30 105.6 0.5 2.5e-30 104.8 0.5 1.4 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 EKX39066.1 - 2.9e-23 81.9 0.0 5.2e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 UPF0113 PUA domain PP1 PF07430.11 EKX39066.1 - 0.00037 20.5 0.0 0.00064 19.7 0.0 1.4 1 0 0 1 1 1 1 Phloem filament protein PP1 cystatin-like domain Atx10homo_assoc PF09759.9 EKX39067.1 - 0.15 12.1 1.6 17 5.5 0.3 2.9 3 1 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 EKX39067.1 - 3.2 7.9 7.6 46 4.3 0.1 4.2 4 1 1 5 5 5 0 Armadillo/beta-catenin-like repeat Histone PF00125.24 EKX39068.1 - 1.6e-17 64.1 0.0 1.8e-17 63.9 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EKX39068.1 - 3.5e-05 24.0 0.0 4.3e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CUB PF00431.20 EKX39070.1 - 0.0015 18.8 0.0 0.008 16.5 0.0 2.3 1 0 0 1 1 1 1 CUB domain Agarase_CBM PF17992.1 EKX39070.1 - 1.3 8.5 13.5 0.52 9.8 0.1 4.5 5 0 0 5 5 5 0 Agarase CBM like domain eIF_4EBP PF05456.11 EKX39074.1 - 0.18 11.8 1.7 9.5 6.2 0.1 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Pkinase PF00069.25 EKX39075.1 - 1.6e-29 103.1 0.0 1.9e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX39075.1 - 7.5e-18 64.7 0.0 8.3e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX39075.1 - 9.5e-05 21.3 0.0 0.00012 21.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EKX39075.1 - 0.11 11.9 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fructosamin_kin PF03881.14 EKX39075.1 - 0.14 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase Sec16 PF12932.7 EKX39076.1 - 2.7 8.6 7.8 0.57 10.8 2.2 2.6 1 1 1 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region Prefoldin_2 PF01920.20 EKX39077.1 - 6.3e-14 51.8 4.0 8.1e-14 51.5 4.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit IFT57 PF10498.9 EKX39077.1 - 0.0031 16.6 5.0 0.38 9.7 0.4 2.0 2 0 0 2 2 2 2 Intra-flagellar transport protein 57 GAS PF13851.6 EKX39077.1 - 0.069 12.5 5.9 0.1 11.9 0.9 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EKX39077.1 - 0.14 11.0 6.2 1.2 8.0 0.4 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein DASH_Dad3 PF08656.10 EKX39077.1 - 0.81 9.8 4.6 2.9 8.1 4.6 2.0 1 1 0 1 1 1 0 DASH complex subunit Dad3 MIF PF01187.18 EKX39078.1 - 4.7e-26 91.3 0.0 5.1e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 EKX39078.1 - 0.0049 16.8 0.0 2.8 7.9 0.0 2.1 2 0 0 2 2 2 2 Tautomerase enzyme RTP801_C PF07809.11 EKX39078.1 - 0.019 14.9 0.0 0.034 14.0 0.0 1.4 2 0 0 2 2 2 0 RTP801 C-terminal region Cys_box PF17869.1 EKX39078.1 - 0.061 13.5 0.1 0.074 13.2 0.1 1.1 1 0 0 1 1 1 0 Anosmin cysteine rich domain PKcGMP_CC PF16808.5 EKX39079.1 - 0.0024 17.7 7.5 2.8 7.9 0.3 4.0 3 1 0 3 3 3 2 Coiled-coil N-terminus of cGMP-dependent protein kinase TetR_C_31 PF17940.1 EKX39079.1 - 0.039 14.2 0.8 2.8 8.2 0.0 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF573 PF04504.14 EKX39079.1 - 0.2 12.3 2.3 0.19 12.4 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF573 Fib_alpha PF08702.10 EKX39079.1 - 0.52 10.5 9.8 0.66 10.2 3.9 2.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF641 PF04859.12 EKX39079.1 - 1.1 9.6 8.6 0.87 9.9 0.3 3.5 2 1 2 4 4 4 0 Plant protein of unknown function (DUF641) TMF_DNA_bd PF12329.8 EKX39079.1 - 3.9 7.5 15.9 3 7.9 1.6 4.2 5 0 0 5 5 5 0 TATA element modulatory factor 1 DNA binding Prominin PF05478.11 EKX39079.1 - 4.5 5.1 7.4 0.72 7.7 0.3 2.1 1 1 1 2 2 2 0 Prominin NYD-SP28 PF14772.6 EKX39079.1 - 7.9 6.6 10.6 0.31 11.1 0.2 3.2 3 0 0 3 3 3 0 Sperm tail S6PP PF05116.13 EKX39080.1 - 2.9e-48 164.6 0.0 1.8e-24 86.6 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 EKX39080.1 - 4.2e-21 75.8 0.0 3.5e-20 72.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EKX39080.1 - 0.0042 17.4 0.0 0.05 13.9 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SSP160 PF06933.11 EKX39080.1 - 4.8 5.3 7.2 6.7 4.8 7.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MOR2-PAG1_C PF14225.6 EKX39081.1 - 1.5e-30 106.9 1.3 1.8e-29 103.4 0.0 3.2 3 0 0 3 3 3 1 Cell morphogenesis C-terminal MOR2-PAG1_N PF14222.6 EKX39081.1 - 7.8e-10 38.3 8.0 6.1e-06 25.5 3.0 2.4 1 1 1 2 2 2 2 Cell morphogenesis N-terminal Luciferase_N PF05295.11 EKX39081.1 - 0.05 13.6 0.0 0.17 11.9 0.0 1.9 1 0 0 1 1 1 0 Luciferase/LBP N-terminal domain HEAT_2 PF13646.6 EKX39081.1 - 0.053 13.9 0.6 6.7 7.2 0.2 3.4 2 0 0 2 2 2 0 HEAT repeats Na_H_Exchanger PF00999.21 EKX39082.1 - 5.6e-05 22.1 8.2 6.9e-05 21.8 8.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.21 EKX39083.1 - 9.9e-09 34.4 3.5 1.1e-08 34.2 3.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DPM3 PF08285.11 EKX39083.1 - 0.059 13.6 0.4 0.13 12.4 0.3 1.6 1 1 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) CUB PF00431.20 EKX39084.1 - 1.3e-06 28.7 0.0 1.2e-05 25.6 0.0 2.8 1 0 0 1 1 1 1 CUB domain KH_1 PF00013.29 EKX39085.1 - 9.7e-10 38.1 1.2 0.0009 19.0 0.0 2.8 2 1 0 2 2 2 2 KH domain Agenet PF05641.12 EKX39085.1 - 3.7e-07 30.5 0.2 8.2e-06 26.2 0.2 2.5 2 0 0 2 2 2 1 Agenet domain KH_2 PF07650.17 EKX39085.1 - 1.4e-05 24.8 1.0 0.0079 16.0 0.4 2.7 2 1 0 2 2 2 2 KH domain KH_4 PF13083.6 EKX39085.1 - 3.2e-05 23.7 0.4 0.17 11.8 0.0 2.8 3 0 0 3 3 3 2 KH domain DUF4404 PF14357.6 EKX39086.1 - 1.8e-05 25.3 23.4 0.39 11.4 2.7 4.8 3 0 0 3 3 3 3 Domain of unknown function (DUF4404) Skp1 PF01466.19 EKX39086.1 - 7.8e-05 22.7 0.0 48 4.2 0.0 4.5 4 0 0 4 4 4 0 Skp1 family, dimerisation domain FlaC_arch PF05377.11 EKX39086.1 - 0.0035 17.7 11.2 16 6.0 0.1 6.0 7 0 0 7 7 7 0 Flagella accessory protein C (FlaC) Spc24 PF08286.11 EKX39086.1 - 0.0049 17.1 27.7 50 4.2 1.6 7.2 7 0 0 7 7 7 0 Spc24 subunit of Ndc80 Fib_alpha PF08702.10 EKX39086.1 - 0.0087 16.2 7.0 13 6.0 0.2 3.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF402 PF04167.13 EKX39086.1 - 0.01 16.0 0.0 1.8e+02 2.4 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF402) PCRF PF03462.18 EKX39086.1 - 0.011 15.6 12.9 4.1 7.2 0.6 4.0 3 0 0 3 3 3 0 PCRF domain CENP-K PF11802.8 EKX39086.1 - 0.015 14.9 9.1 6.3 6.3 0.3 3.5 3 0 0 3 3 3 0 Centromere-associated protein K Nsp1_C PF05064.13 EKX39086.1 - 0.046 13.5 10.4 11 5.8 0.4 4.0 3 0 0 3 3 3 0 Nsp1-like C-terminal region HIP1_clath_bdg PF16515.5 EKX39086.1 - 0.069 13.8 24.7 1.8 9.2 0.6 6.1 7 0 0 7 7 7 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Gp58 PF07902.11 EKX39086.1 - 0.087 11.1 20.4 1.4 7.1 1.9 3.5 4 0 0 4 4 4 0 gp58-like protein Prp18 PF02840.15 EKX39086.1 - 0.34 10.9 3.6 1.4e+02 2.5 0.1 4.8 3 0 0 3 3 3 0 Prp18 domain ATG_C PF09333.11 EKX39086.1 - 0.51 10.7 2.2 2.4e+02 2.1 0.0 5.1 4 0 0 4 4 4 0 Autophagy-related protein C terminal domain Occludin_ELL PF07303.13 EKX39086.1 - 2.2 9.1 15.5 27 5.6 0.2 5.3 7 0 0 7 7 3 0 Occludin homology domain FOXP-CC PF16159.5 EKX39086.1 - 2.5 8.8 14.5 30 5.3 0.8 4.0 3 0 0 3 3 3 0 FOXP coiled-coil domain DUF4615 PF15393.6 EKX39086.1 - 3.6 8.2 23.2 13 6.3 2.6 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4615) Phage_GPO PF05929.11 EKX39086.1 - 5.3 6.6 25.3 8.6 5.9 3.3 3.7 3 0 0 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF3464 PF11947.8 EKX39086.1 - 5.6 6.7 8.6 60 3.4 0.2 3.4 3 0 0 3 3 3 0 Photosynthesis affected mutant 68 Phenyl_P_gamma PF09662.10 EKX39086.1 - 7 6.9 7.2 1.4e+02 2.7 0.2 3.8 3 0 0 3 3 3 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) TMF_TATA_bd PF12325.8 EKX39086.1 - 8.1 6.7 30.6 16 5.7 2.6 6.9 7 0 0 7 7 7 0 TATA element modulatory factor 1 TATA binding PaREP1 PF05942.11 EKX39086.1 - 8.9 6.3 18.3 34 4.4 1.4 4.9 3 0 0 3 3 3 0 Archaeal PaREP1/PaREP8 family HIRAN PF08797.11 EKX39087.1 - 5.5e-11 42.2 0.0 1.4e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain TPR_19 PF14559.6 EKX39087.1 - 5.3e-08 33.3 7.7 0.003 18.1 0.3 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX39087.1 - 1.5e-07 31.3 2.2 0.0031 17.8 0.8 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX39087.1 - 7.2e-07 29.5 2.1 0.066 14.1 0.1 3.8 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX39087.1 - 4.9e-05 23.1 0.5 0.53 10.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX39087.1 - 0.00024 21.7 3.0 0.099 13.3 0.1 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX39087.1 - 0.0058 16.8 0.5 0.72 10.2 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX39087.1 - 0.19 12.0 1.3 8.5 6.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 EKX39087.1 - 0.55 9.9 2.2 0.89 9.2 0.8 2.0 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_11 PF13414.6 EKX39087.1 - 1.2 8.9 6.0 2.1 8.1 0.6 2.8 2 0 0 2 2 2 0 TPR repeat AAA_22 PF13401.6 EKX39088.1 - 0.0002 21.7 0.0 0.0084 16.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.13 EKX39088.1 - 0.0059 15.8 0.1 0.014 14.6 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF815) Rad17 PF03215.15 EKX39088.1 - 0.0084 16.0 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 EKX39088.1 - 0.015 15.0 0.1 0.03 14.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EKX39088.1 - 0.025 15.0 0.0 0.065 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EKX39088.1 - 0.025 15.1 0.0 0.33 11.4 0.0 2.3 2 0 0 2 2 2 0 ABC transporter PIF1 PF05970.14 EKX39088.1 - 0.028 13.6 0.0 0.059 12.5 0.0 1.5 1 0 0 1 1 1 0 PIF1-like helicase RsgA_GTPase PF03193.16 EKX39088.1 - 0.033 14.1 0.1 0.086 12.7 0.1 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 EKX39088.1 - 0.034 14.6 0.0 0.11 12.9 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EKX39088.1 - 0.056 13.0 0.0 0.57 9.7 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 EKX39088.1 - 0.069 13.7 0.0 0.24 12.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 EKX39088.1 - 0.069 13.5 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 EKX39088.1 - 0.082 12.8 0.1 0.31 10.9 0.1 2.0 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 EKX39088.1 - 0.088 12.8 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EKX39088.1 - 0.14 12.3 0.1 0.31 11.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EKX39088.1 - 0.17 11.1 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin FtsK_SpoIIIE PF01580.18 EKX39088.1 - 0.22 10.8 1.1 0.44 9.9 0.2 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family URO-D PF01208.17 EKX39089.1 - 1e-65 222.2 0.0 1.3e-65 221.9 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Zeta_toxin PF06414.12 EKX39091.1 - 7.3e-24 84.1 0.0 1.1e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin Glutaredoxin PF00462.24 EKX39091.1 - 5.3e-07 29.8 0.1 2.7e-06 27.5 0.3 2.1 2 0 0 2 2 2 1 Glutaredoxin AAA_33 PF13671.6 EKX39091.1 - 0.0021 18.2 0.0 0.0035 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain GST_N_4 PF17172.4 EKX39091.1 - 0.0063 17.2 0.1 0.19 12.5 0.0 2.9 3 0 0 3 3 3 1 Glutathione S-transferase N-terminal domain Thioredoxin_2 PF13098.6 EKX39091.1 - 0.02 15.3 0.0 3.4 8.2 0.3 3.1 2 1 0 2 2 2 0 Thioredoxin-like domain DUF836 PF05768.14 EKX39091.1 - 0.076 13.4 1.2 1.4 9.4 0.6 2.5 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) DASH_Duo1 PF08651.10 EKX39093.1 - 0.012 15.4 0.9 0.017 14.8 0.9 1.2 1 0 0 1 1 1 0 DASH complex subunit Duo1 FTO_NTD PF12933.7 EKX39093.1 - 0.15 11.3 1.9 0.18 11.1 1.9 1.2 1 0 0 1 1 1 0 FTO catalytic domain MAT1 PF06391.13 EKX39093.1 - 0.34 10.7 5.1 0.45 10.3 5.1 1.1 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 TMPIT PF07851.13 EKX39093.1 - 0.65 9.2 1.8 3.2 6.9 3.2 1.4 2 0 0 2 2 2 0 TMPIT-like protein HK PF02110.15 EKX39095.1 - 4e-73 245.8 6.6 5.4e-73 245.4 6.6 1.2 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 EKX39095.1 - 0.0033 16.8 2.7 0.0055 16.1 0.9 2.1 1 1 1 2 2 2 1 Phosphomethylpyrimidine kinase PDZ PF00595.24 EKX39096.1 - 2.1e-10 40.8 0.4 3e-10 40.3 0.4 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX39096.1 - 3.4e-10 40.1 0.3 4.5e-10 39.7 0.3 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX39096.1 - 4.6e-07 29.6 0.0 6.5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Exo_endo_phos PF03372.23 EKX39097.1 - 2.1e-12 47.0 0.0 3.1e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_L18A PF01775.17 EKX39097.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Exo_endo_phos_2 PF14529.6 EKX39097.1 - 0.15 11.9 0.0 0.6 10.0 0.0 2.0 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Glycos_transf_4 PF00953.21 EKX39098.1 - 6.3e-35 120.5 13.4 6.3e-35 120.5 13.4 2.1 3 0 0 3 3 3 1 Glycosyl transferase family 4 NmrA PF05368.13 EKX39100.1 - 1.1e-40 139.6 0.0 1.4e-40 139.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EKX39100.1 - 4e-12 46.4 0.0 6.4e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EKX39100.1 - 5.1e-08 32.7 0.1 9.4e-08 31.8 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EKX39100.1 - 2.9e-05 23.6 0.0 5.9e-05 22.6 0.0 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase KR PF08659.10 EKX39100.1 - 0.0039 17.1 0.1 0.0073 16.2 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EKX39100.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.19 EKX39100.1 - 0.028 13.4 0.0 0.038 13.0 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 EKX39100.1 - 0.036 14.6 0.1 0.096 13.3 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 EKX39100.1 - 0.075 13.2 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 EKX39101.1 - 1.2e-14 54.5 0.1 2.2e-10 40.5 0.1 2.1 2 0 0 2 2 2 2 NmrA-like family Epimerase PF01370.21 EKX39101.1 - 2.6e-08 33.6 0.0 4.7e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EKX39101.1 - 3.3e-07 30.4 0.2 5.9e-07 29.6 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EKX39101.1 - 1.6e-05 24.4 0.0 3.4e-05 23.4 0.0 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase KR PF08659.10 EKX39101.1 - 0.004 17.1 0.2 0.0062 16.5 0.2 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EKX39101.1 - 0.014 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase F420_oxidored PF03807.17 EKX39101.1 - 0.024 15.2 0.1 0.053 14.1 0.1 1.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 EKX39101.1 - 0.059 13.5 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 EKX39102.1 - 1.1e-40 139.6 0.0 1.4e-40 139.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EKX39102.1 - 4e-12 46.4 0.0 6.4e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EKX39102.1 - 5.1e-08 32.7 0.1 9.4e-08 31.8 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EKX39102.1 - 2.8e-05 23.7 0.1 5.9e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase KR PF08659.10 EKX39102.1 - 0.0039 17.1 0.1 0.0073 16.2 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EKX39102.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.19 EKX39102.1 - 0.028 13.4 0.0 0.038 13.0 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 EKX39102.1 - 0.036 14.6 0.1 0.096 13.3 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 EKX39102.1 - 0.076 13.1 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 EKX39103.1 - 1.1e-40 139.6 0.0 1.4e-40 139.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EKX39103.1 - 4e-12 46.4 0.0 6.4e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EKX39103.1 - 5.6e-08 32.5 0.1 9.4e-08 31.8 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EKX39103.1 - 3e-05 23.6 0.0 5.9e-05 22.6 0.0 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase KR PF08659.10 EKX39103.1 - 0.0039 17.1 0.1 0.0073 16.2 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EKX39103.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.19 EKX39103.1 - 0.028 13.4 0.0 0.038 13.0 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 EKX39103.1 - 0.036 14.6 0.1 0.096 13.3 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 EKX39103.1 - 0.075 13.2 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PHM7_cyt PF14703.6 EKX39104.1 - 2e-22 80.3 0.0 5.3e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EKX39104.1 - 3e-08 33.6 0.7 3e-08 33.6 0.7 3.2 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport RSN1_7TM PF02714.15 EKX39104.1 - 4.6e-08 32.7 24.0 4.6e-08 32.7 24.0 1.9 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate DUF4523 PF15023.6 EKX39104.1 - 0.0014 18.5 0.0 0.0036 17.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) Ribosomal_60s PF00428.19 EKX39104.1 - 0.031 14.9 15.4 0.11 13.1 15.4 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein RRM_1 PF00076.22 EKX39104.1 - 0.12 12.2 0.1 0.68 9.8 0.1 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1712 PF08217.11 EKX39105.1 - 2.1e-46 158.7 0.1 2.4e-37 128.7 0.0 2.8 2 1 0 3 3 3 2 Fungal domain of unknown function (DUF1712) SAND PF01342.21 EKX39106.1 - 0.075 12.7 1.0 4 7.2 0.2 2.5 2 0 0 2 2 2 0 SAND domain RAI1 PF08652.11 EKX39109.1 - 8.9e-26 89.9 0.1 1.8e-25 88.9 0.1 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease PH PF00169.29 EKX39110.1 - 0.00011 22.6 0.5 0.00047 20.6 0.1 2.3 2 0 0 2 2 2 1 PH domain Phage_GP20 PF06810.11 EKX39110.1 - 0.032 14.1 1.4 0.032 14.1 1.4 2.9 2 1 0 2 2 2 0 Phage minor structural protein GP20 FtsX_ECD PF18075.1 EKX39110.1 - 0.49 11.1 4.4 3.8 8.2 4.3 2.6 1 1 0 1 1 1 0 FtsX extracellular domain DUF4611 PF15387.6 EKX39110.1 - 5.4 7.3 10.4 0.44 10.8 2.8 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4611) CorA PF01544.18 EKX39110.1 - 6.4 6.0 8.6 6.4 6.0 0.4 2.9 1 1 1 3 3 3 0 CorA-like Mg2+ transporter protein DUF4407 PF14362.6 EKX39110.1 - 8.5 5.6 14.2 4 6.7 3.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) PseudoU_synth_2 PF00849.22 EKX39111.1 - 8.5e-27 94.2 0.0 1.5e-26 93.4 0.0 1.4 1 1 0 1 1 1 1 RNA pseudouridylate synthase FAA_hydrolase PF01557.18 EKX39112.1 - 9.2e-55 185.7 0.0 1.1e-54 185.5 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family KH_2 PF07650.17 EKX39112.1 - 0.027 14.3 0.2 0.027 14.3 0.2 1.8 2 0 0 2 2 2 0 KH domain KH_4 PF13083.6 EKX39112.1 - 0.049 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 KH domain Guanylate_cyc PF00211.20 EKX39113.1 - 2.8e-27 95.5 0.5 6.8e-27 94.3 0.5 1.6 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_3 PF08447.12 EKX39113.1 - 0.0096 16.2 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EKX39113.1 - 0.038 14.0 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 PAS domain PAS_12 PF18095.1 EKX39113.1 - 0.045 13.4 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain Methyltransf_21 PF05050.12 EKX39114.1 - 2.6e-08 34.1 0.0 3.2e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase FkbM domain ARL2_Bind_BART PF11527.8 EKX39115.1 - 1.2e-09 38.3 2.2 1.2e-09 38.3 2.2 2.4 3 0 0 3 3 3 1 The ARF-like 2 binding protein BART DNA_pol_phi PF04931.13 EKX39115.1 - 0.00012 20.3 27.4 0.00021 19.6 27.4 1.4 1 0 0 1 1 1 1 DNA polymerase phi RRN3 PF05327.11 EKX39115.1 - 0.00039 19.1 15.4 0.0006 18.5 15.4 1.3 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 EKX39115.1 - 0.0036 15.7 11.7 0.006 15.0 11.7 1.3 1 0 0 1 1 1 1 CDC45-like protein BUD22 PF09073.10 EKX39115.1 - 0.0039 16.6 14.7 0.0058 16.0 14.7 1.4 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 EKX39115.1 - 0.0045 15.3 22.6 0.0066 14.7 22.6 1.2 1 0 0 1 1 1 1 Nop14-like family IQ PF00612.27 EKX39115.1 - 0.017 14.9 2.5 0.096 12.5 2.5 2.3 1 0 0 1 1 1 0 IQ calmodulin-binding motif DUF4783 PF16022.5 EKX39115.1 - 0.023 14.8 0.2 0.023 14.8 0.2 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4783) SDA1 PF05285.12 EKX39115.1 - 0.14 11.6 26.2 1.4 8.3 25.8 2.2 2 0 0 2 2 2 0 SDA1 CNDH2_C PF16858.5 EKX39115.1 - 0.29 11.0 14.0 0.14 12.0 11.0 2.0 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term RPN2_C PF18004.1 EKX39115.1 - 0.81 9.6 7.8 1.8 8.5 7.8 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RNase_H2_suC PF08615.11 EKX39115.1 - 4.5 7.5 5.7 17 5.6 5.7 2.0 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF2076 PF09849.9 EKX39115.1 - 7.7 6.5 22.1 17 5.3 22.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) LRR_6 PF13516.6 EKX39116.1 - 1.4e-11 43.5 10.1 0.00043 20.1 0.7 4.3 4 0 0 4 4 4 4 Leucine Rich repeat CLP1_P PF16575.5 EKX39116.1 - 0.14 12.0 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF2958 PF11171.8 EKX39116.1 - 0.16 12.2 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2958) HEAT PF02985.22 EKX39117.1 - 2e-11 43.1 12.6 0.0029 17.7 0.1 6.5 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 EKX39117.1 - 2.8e-10 40.5 3.5 9.5e-09 35.5 0.1 4.9 4 2 2 6 6 6 2 HEAT repeats Cnd1 PF12717.7 EKX39117.1 - 1.4e-07 31.7 10.7 3.6e-06 27.1 1.8 3.6 2 2 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EKX39117.1 - 5.7e-07 28.5 1.8 3.1e-06 26.1 0.1 2.1 2 0 0 2 2 2 1 Adaptin N terminal region HEAT_EZ PF13513.6 EKX39117.1 - 3.4e-06 27.4 5.0 0.00071 20.0 0.6 5.2 4 1 1 5 5 5 1 HEAT-like repeat RTP1_C1 PF10363.9 EKX39117.1 - 1.2e-05 25.4 0.6 0.0032 17.7 0.2 3.1 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Cohesin_HEAT PF12765.7 EKX39117.1 - 1.4e-05 25.3 2.4 0.0048 17.2 0.1 2.9 1 1 1 2 2 2 2 HEAT repeat associated with sister chromatid cohesion DUF4042 PF13251.6 EKX39117.1 - 0.061 13.0 2.2 7 6.3 0.0 3.6 2 2 2 4 4 4 0 Domain of unknown function (DUF4042) DUF3730 PF12530.8 EKX39117.1 - 0.18 11.3 2.7 1.7 8.2 0.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3730) HYLS1_C PF15311.6 EKX39120.1 - 1.3 9.9 5.4 0.69 10.7 1.1 2.4 1 1 2 3 3 3 0 Hydrolethalus syndrome protein 1 C-terminus Ank PF00023.30 EKX39121.1 - 1.3e-22 79.2 3.3 1.1e-07 31.9 0.0 5.1 4 1 1 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EKX39121.1 - 2.8e-20 70.2 0.6 4.1e-05 23.6 0.1 5.4 5 1 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 EKX39121.1 - 1.3e-19 70.5 0.0 1.1e-10 41.9 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX39121.1 - 3.1e-18 65.6 0.7 5e-08 33.1 0.0 4.3 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX39121.1 - 1.5e-17 63.7 0.0 1.6e-07 31.7 0.0 4.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) UDG PF03167.19 EKX39122.1 - 4.3e-22 78.8 0.0 6.4e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily HSP70 PF00012.20 EKX39123.1 - 1.8e-42 145.3 17.6 7e-42 143.4 0.0 2.8 2 1 1 3 3 3 2 Hsp70 protein TPR_1 PF00515.28 EKX39123.1 - 0.0063 16.3 1.8 0.38 10.7 0.1 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat HicB_lk_antitox PF15919.5 EKX39123.1 - 0.051 13.7 1.5 0.86 9.7 0.5 2.4 2 0 0 2 2 2 0 HicB_like antitoxin of bacterial toxin-antitoxin system TPR_2 PF07719.17 EKX39123.1 - 0.1 12.8 5.0 0.21 11.8 0.5 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 EKX39123.1 - 0.25 11.4 6.5 1.2 9.2 0.0 3.5 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 EKX39123.1 - 0.57 10.7 3.6 0.47 11.0 0.3 2.6 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF4407 PF14362.6 EKX39123.1 - 0.64 9.3 4.8 1.3 8.3 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fis1_TPR_C PF14853.6 EKX39123.1 - 0.7 10.0 2.9 1.1 9.4 0.8 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat DUF1664 PF07889.12 EKX39123.1 - 1.6 8.7 8.5 4.1 7.5 6.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Globin PF00042.22 EKX39124.1 - 9.1e-06 26.2 0.0 0.00038 21.0 0.0 2.5 1 1 1 2 2 2 1 Globin Cyt-b5 PF00173.28 EKX39125.1 - 4.6e-13 49.1 0.0 5e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Globin PF00042.22 EKX39126.1 - 2.6e-14 53.7 0.0 0.00011 22.7 0.0 4.6 3 2 0 3 3 3 3 Globin Cyt-b5 PF00173.28 EKX39126.1 - 1e-12 48.0 0.0 2.5e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HEAT PF02985.22 EKX39127.1 - 2.4e-30 102.0 15.1 7e-06 25.9 0.1 7.5 7 0 0 7 7 7 6 HEAT repeat HEAT_2 PF13646.6 EKX39127.1 - 1.1e-26 93.0 20.4 2.8e-11 43.6 1.0 5.2 3 1 2 5 5 5 5 HEAT repeats HEAT_EZ PF13513.6 EKX39127.1 - 2.7e-09 37.3 14.8 0.00075 20.0 1.3 5.8 2 2 4 6 6 6 5 HEAT-like repeat API5 PF05918.11 EKX39127.1 - 3.2e-09 36.2 0.2 8.8e-06 24.8 0.0 3.5 3 1 1 4 4 4 1 Apoptosis inhibitory protein 5 (API5) RTP1_C1 PF10363.9 EKX39127.1 - 2.5e-08 34.1 0.0 0.36 11.0 0.1 4.1 2 1 0 2 2 2 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 EKX39127.1 - 6.7e-06 26.2 1.1 0.049 13.7 0.1 3.5 1 1 2 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EKX39127.1 - 8e-06 24.7 3.6 0.28 9.7 0.1 3.7 1 1 1 3 3 3 3 Adaptin N terminal region DNA_alkylation PF08713.11 EKX39127.1 - 7.8e-05 22.5 3.1 0.0054 16.5 2.4 3.1 2 1 1 3 3 3 1 DNA alkylation repair enzyme Vac14_Fab1_bd PF12755.7 EKX39127.1 - 9.7e-05 22.9 0.0 0.43 11.2 0.0 3.4 3 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region TAF6_C PF07571.13 EKX39127.1 - 0.002 18.4 1.2 6.6 7.1 0.3 4.1 1 1 1 2 2 2 1 TAF6 C-terminal HEAT repeat domain HEAT_PBS PF03130.16 EKX39127.1 - 0.016 15.8 16.7 14 6.7 0.1 7.3 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat RACo_linker PF17650.1 EKX39127.1 - 0.04 13.8 0.3 0.7 9.8 0.0 3.0 4 0 0 4 4 4 0 RACo linker region V-ATPase_H_C PF11698.8 EKX39127.1 - 0.048 13.8 1.8 35 4.5 0.1 4.1 3 1 0 4 4 4 0 V-ATPase subunit H RICTOR_V PF14668.6 EKX39127.1 - 0.072 13.3 0.0 7.2 6.9 0.0 3.4 2 1 2 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 LpxI_N PF17930.1 EKX39127.1 - 0.097 12.6 0.3 4 7.3 0.0 2.7 2 0 0 2 2 2 0 LpxI N-terminal domain PP1_inhibitor PF05361.12 EKX39127.1 - 0.11 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 PKC-activated protein phosphatase-1 inhibitor RasGEF_N_2 PF14663.6 EKX39127.1 - 0.78 10.2 3.2 60 4.1 0.0 4.2 3 1 2 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain CrgA PF06781.12 EKX39128.1 - 0.047 13.7 0.0 0.093 12.8 0.0 1.4 1 0 0 1 1 1 0 Cell division protein CrgA CDC45 PF02724.14 EKX39129.1 - 1.1 7.4 9.5 1.4 7.1 9.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Methyltransf_16 PF10294.9 EKX39130.1 - 4.5e-11 42.8 0.0 1.8e-05 24.6 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_12 PF08242.12 EKX39130.1 - 4.4e-05 24.1 0.1 0.00039 21.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX39130.1 - 0.00011 22.0 0.2 0.00062 19.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX39130.1 - 0.00054 19.8 0.0 0.00085 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 EKX39130.1 - 0.19 11.4 0.0 0.61 9.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Aminotran_5 PF00266.19 EKX39131.1 - 1.8e-21 76.6 0.0 1.3e-11 44.1 0.0 2.6 2 1 0 2 2 2 2 Aminotransferase class-V MOSC_N PF03476.16 EKX39131.1 - 9.3e-06 25.5 0.1 5.5e-05 23.0 0.1 2.2 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain Helicase_C PF00271.31 EKX39133.1 - 3.6e-13 49.8 0.0 9.2e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EKX39133.1 - 2.9e-10 40.2 0.0 5.9e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase NACHT PF05729.12 EKX39133.1 - 0.00034 20.6 0.1 0.0015 18.4 0.0 2.1 2 0 0 2 2 2 1 NACHT domain ATPase PF06745.13 EKX39133.1 - 0.0071 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 KaiC T2SSE PF00437.20 EKX39133.1 - 0.015 14.4 0.0 0.036 13.1 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 EKX39133.1 - 0.024 14.9 0.5 0.099 12.9 0.5 2.1 1 1 0 1 1 1 0 AAA domain R3H PF01424.22 EKX39133.1 - 0.034 14.1 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 R3H domain AAA_16 PF13191.6 EKX39133.1 - 0.041 14.3 0.1 0.11 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.6 EKX39133.1 - 0.075 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cupin_8 PF13621.6 EKX39134.1 - 1.3e-24 87.3 0.0 5e-13 49.4 0.0 2.5 1 1 1 2 2 2 2 Cupin-like domain Cupin_4 PF08007.12 EKX39134.1 - 3.1e-05 23.6 0.1 5.6e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 EKX39134.1 - 0.0016 18.9 0.1 0.0029 18.0 0.1 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase Kdo PF06293.14 EKX39134.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ATP_bind_2 PF03668.15 EKX39135.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop ATPase protein family TFIIA PF03153.13 EKX39135.1 - 6.9 6.5 13.7 7.9 6.4 13.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ephrin_rec_like PF07699.13 EKX39136.1 - 6.2e-51 169.9 80.3 2.9e-11 43.0 0.5 7.8 4 2 3 8 8 8 8 Putative ephrin-receptor like NCD3G PF07562.14 EKX39136.1 - 8.4e-07 28.9 64.9 0.058 13.4 8.1 7.3 4 2 5 9 9 9 9 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX39136.1 - 0.0091 16.4 68.6 0.87 10.0 2.7 11.0 5 4 5 10 10 10 8 TNFR/NGFR cysteine-rich region Pico_P2A PF00947.19 EKX39136.1 - 0.2 11.6 12.8 2.3 8.2 0.4 3.3 3 0 0 3 3 3 0 Picornavirus core protein 2A Ephrin_rec_like PF07699.13 EKX39137.1 - 1.4e-34 117.6 45.2 1e-12 47.6 7.3 4.5 4 0 0 4 4 4 4 Putative ephrin-receptor like EGF_3 PF12947.7 EKX39137.1 - 0.026 14.7 4.6 0.026 14.7 4.6 5.9 5 0 0 5 5 5 0 EGF domain hEGF PF12661.7 EKX39137.1 - 0.03 15.0 22.5 1.1 10.0 0.0 6.9 6 0 0 6 6 6 0 Human growth factor-like EGF SHS2_Rpb7-N PF03876.17 EKX39139.1 - 0.12 12.8 0.2 0.32 11.4 0.0 1.8 2 0 0 2 2 2 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DNA_ligase_A_M PF01068.21 EKX39140.1 - 0.092 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 ATP dependent DNA ligase domain Circo_capsid PF02443.15 EKX39140.1 - 0.17 11.4 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Circovirus capsid protein Ogr_Delta PF04606.12 EKX39141.1 - 0.027 14.4 1.6 0.069 13.1 1.6 1.7 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger Cas_Csa4 PF09703.10 EKX39142.1 - 0.012 14.9 0.0 0.015 14.7 0.0 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa4) DUF604 PF04646.12 EKX39142.1 - 0.15 11.4 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF604 CTU2 PF10288.9 EKX39143.1 - 0.26 11.5 6.5 15 5.9 3.8 2.7 2 1 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 bVLRF1 PF18826.1 EKX39144.1 - 2.2e-32 112.0 1.5 3.7e-32 111.3 0.0 2.0 2 0 0 2 2 2 1 bacteroidetes VLRF1 release factor VATC PF18716.1 EKX39144.1 - 2.1e-07 30.7 1.4 4.1e-07 29.8 1.4 1.5 1 0 0 1 1 1 1 Vms1-associating treble clef domain SPATA3 PF15662.5 EKX39144.1 - 0.45 11.1 6.2 1 10.0 6.2 1.6 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family DDHD PF02862.17 EKX39144.1 - 1.2 9.2 7.9 0.51 10.5 3.3 2.1 2 0 0 2 2 2 0 DDHD domain CPSF100_C PF13299.6 EKX39144.1 - 1.8 8.7 13.0 4.1 7.6 9.2 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF3464 PF11947.8 EKX39144.1 - 6.5 6.5 13.0 21 4.8 13.0 1.8 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Neur_chan_memb PF02932.16 EKX39144.1 - 6.8 6.7 7.6 1.4 8.9 3.8 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SET PF00856.28 EKX39144.1 - 7 7.0 6.7 2 8.8 2.4 2.2 2 1 0 2 2 2 0 SET domain DUF913 PF06025.12 EKX39144.1 - 7.3 5.5 7.5 0.63 9.0 2.0 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Aquarius_N PF16399.5 EKX39148.1 - 8.1e-260 864.3 4.3 2.2e-259 862.8 4.3 1.7 1 1 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 EKX39148.1 - 5.3e-30 105.1 4.8 2.7e-28 99.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.6 EKX39148.1 - 2e-25 89.6 0.0 5.5e-25 88.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain SAP PF02037.27 EKX39148.1 - 7.8e-12 44.7 0.5 7.8e-12 44.7 0.5 2.5 2 0 0 2 2 2 1 SAP domain AAA_19 PF13245.6 EKX39148.1 - 3e-08 34.1 0.0 1.8e-07 31.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EKX39148.1 - 1.2e-06 28.4 0.0 0.0025 17.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 EKX39148.1 - 0.0007 19.6 0.0 0.0028 17.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA PF00004.29 EKX39148.1 - 0.021 15.3 0.0 0.053 13.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 EKX39148.1 - 0.07 13.0 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain CDC27 PF09507.10 EKX39148.1 - 0.097 12.0 46.5 0.16 11.3 46.5 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PhoH PF02562.16 EKX39148.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein CDC45 PF02724.14 EKX39148.1 - 0.38 9.0 12.1 0.74 8.0 12.1 1.4 1 0 0 1 1 1 0 CDC45-like protein Cys_Met_Meta_PP PF01053.20 EKX39149.1 - 1.6e-52 178.4 0.0 1.9e-52 178.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Sel1 PF08238.12 EKX39150.1 - 2.5e-49 164.6 23.0 1.4e-09 38.3 0.0 9.0 9 0 0 9 9 9 8 Sel1 repeat TPR_6 PF13174.6 EKX39150.1 - 0.0041 17.6 4.0 34 5.4 0.1 5.8 5 1 1 6 6 6 1 Tetratricopeptide repeat Enolase_like_N PF18374.1 EKX39150.1 - 0.0071 15.7 3.0 0.83 9.1 0.0 3.2 3 0 0 3 3 3 2 Enolase N-terminal domain-like Cyt-b5 PF00173.28 EKX39151.1 - 1.7e-15 56.9 0.0 2.1e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Globin PF00042.22 EKX39152.1 - 6.6e-06 26.6 0.0 6.7e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 Globin Peptidase_U32 PF01136.19 EKX39154.1 - 0.083 12.0 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Peptidase family U32 Glyco_transf_17 PF04724.13 EKX39155.1 - 3.9e-45 154.4 0.7 5e-45 154.1 0.7 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 17 fn3 PF00041.21 EKX39156.1 - 7e-14 51.9 0.2 0.0014 18.9 0.0 4.1 3 1 0 3 3 3 3 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 EKX39156.1 - 0.012 16.1 1.0 27 5.4 0.0 3.8 3 2 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain Atg14 PF10186.9 EKX39158.1 - 0.27 10.3 4.5 0.57 9.2 4.5 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HemY_N PF07219.13 EKX39158.1 - 0.27 11.4 3.8 1.3 9.2 2.2 2.7 2 0 0 2 2 2 0 HemY protein N-terminus HK97-gp10_like PF04883.12 EKX39158.1 - 0.58 11.2 11.7 8.2 7.5 0.3 4.3 2 1 0 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component P21-Arc PF04062.14 EKX39159.1 - 6.2e-57 192.4 0.1 6.7e-57 192.3 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit NHL PF01436.21 EKX39160.1 - 3.9e-18 64.5 6.2 3.2e-05 23.8 0.0 5.0 5 0 0 5 5 5 4 NHL repeat SGL PF08450.12 EKX39160.1 - 8.9e-10 38.6 0.0 0.0045 16.6 0.0 4.5 2 1 3 5 5 5 4 SMP-30/Gluconolactonase/LRE-like region DUF5128 PF17170.4 EKX39160.1 - 1.1e-07 31.3 0.1 0.021 14.0 0.0 3.1 3 1 0 3 3 3 2 6-bladed beta-propeller Phytase-like PF13449.6 EKX39160.1 - 9.3e-07 29.1 0.0 2.2 8.2 0.0 4.1 3 2 0 3 3 3 3 Esterase-like activity of phytase MRJP PF03022.16 EKX39160.1 - 0.0027 17.1 0.9 5.6 6.2 0.1 3.7 3 1 0 4 4 4 2 Major royal jelly protein SBBP PF06739.11 EKX39160.1 - 0.005 16.8 0.0 10 6.2 0.0 3.8 4 0 0 4 4 4 1 Beta-propeller repeat Arylesterase PF01731.20 EKX39160.1 - 0.15 12.3 0.0 14 6.0 0.0 3.3 4 0 0 4 4 4 0 Arylesterase LVIVD PF08309.11 EKX39160.1 - 0.28 10.6 1.9 2.1 7.7 0.2 2.6 2 0 0 2 2 2 0 LVIVD repeat PX PF00787.24 EKX39161.1 - 1.2e-15 57.4 0.2 1.7e-15 57.0 0.2 1.2 1 0 0 1 1 1 1 PX domain EF-1_beta_acid PF10587.9 EKX39161.1 - 0.4 11.2 2.6 1 9.9 2.6 1.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region DEAD_2 PF06733.15 EKX39162.1 - 3.2e-49 166.9 1.1 8e-49 165.6 0.2 2.0 2 0 0 2 2 2 1 DEAD_2 Helicase_C_2 PF13307.6 EKX39162.1 - 7.8e-29 101.0 0.2 4e-27 95.5 0.0 3.2 3 1 1 4 4 4 1 Helicase C-terminal domain HBB PF06777.11 EKX39162.1 - 9.2e-20 71.1 0.8 3.9e-14 52.8 0.1 3.2 2 1 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 EKX39162.1 - 0.0074 16.3 0.0 0.12 12.4 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Zot PF05707.12 EKX39162.1 - 0.022 14.4 0.1 0.78 9.3 0.0 2.5 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) SNF2_N PF00176.23 EKX39162.1 - 0.081 11.6 0.0 0.35 9.5 0.0 1.9 1 1 0 1 1 1 0 SNF2 family N-terminal domain SAM_1 PF00536.30 EKX39164.1 - 8.8e-06 26.1 0.0 2.7e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NUC153 PF08159.12 EKX39164.1 - 2.9e-05 23.8 0.4 6.8e-05 22.6 0.4 1.7 1 0 0 1 1 1 1 NUC153 domain SAM_2 PF07647.17 EKX39164.1 - 6.5e-05 23.0 0.3 0.00058 19.9 0.0 2.7 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 EKX39164.1 - 0.008 16.1 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain AAA_6 PF12774.7 EKX39168.1 - 4.5e-135 449.8 1.9 6.1e-132 439.5 0.0 4.4 5 0 0 5 5 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EKX39168.1 - 2.3e-110 369.5 7.1 2.3e-110 369.5 7.1 5.8 7 0 0 7 7 5 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 EKX39168.1 - 5.5e-81 272.9 17.2 5.5e-81 272.9 17.2 4.3 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_9 PF12781.7 EKX39168.1 - 2.6e-71 239.2 0.0 2.6e-71 239.2 0.0 4.2 3 1 1 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 EKX39168.1 - 7.9e-70 235.1 0.0 3.5e-69 233.0 0.0 2.3 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 EKX39168.1 - 8.1e-45 152.6 0.0 2.6e-36 124.8 0.0 4.6 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 EKX39168.1 - 6.3e-35 120.8 4.1 1.2e-34 119.9 4.1 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 EKX39168.1 - 1.2e-30 106.5 0.0 4.3e-30 104.7 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EKX39168.1 - 4.3e-28 98.0 0.0 6e-11 42.5 0.0 6.5 5 2 0 5 5 5 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 EKX39168.1 - 1.6e-24 86.3 0.0 1.4e-23 83.2 0.0 2.9 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA PF00004.29 EKX39168.1 - 1e-19 71.3 0.0 0.00014 22.3 0.0 5.1 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) Dynein_AAA_lid PF17852.1 EKX39168.1 - 5.8e-18 65.2 0.0 3.4e-17 62.7 0.0 2.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 EKX39168.1 - 3.8e-16 59.6 2.9 0.0018 18.5 0.0 6.9 6 0 0 6 6 5 4 AAA domain AAA_16 PF13191.6 EKX39168.1 - 1.2e-14 55.0 0.5 0.12 12.8 0.0 7.1 5 1 1 6 6 5 4 AAA ATPase domain AAA_33 PF13671.6 EKX39168.1 - 3.6e-10 40.2 0.2 0.18 12.0 0.0 5.2 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.6 EKX39168.1 - 1.4e-08 35.3 0.1 1.9 9.0 0.0 5.8 5 0 0 5 5 4 1 AAA domain Dynein_C PF18199.1 EKX39168.1 - 4.7e-08 32.6 0.1 4.7e-08 32.6 0.1 3.9 3 0 0 3 3 2 1 Dynein heavy chain C-terminal domain AAA_30 PF13604.6 EKX39168.1 - 7.8e-07 29.0 0.0 0.59 9.8 0.0 4.5 4 0 0 4 4 4 1 AAA domain IstB_IS21 PF01695.17 EKX39168.1 - 1e-06 28.6 1.9 1.4 8.6 0.0 5.9 6 0 0 6 6 6 2 IstB-like ATP binding protein AAA_lid_1 PF17857.1 EKX39168.1 - 0.0001 22.4 0.0 0.00094 19.4 0.0 2.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_lid_7 PF17867.1 EKX39168.1 - 0.00019 21.6 0.8 0.00019 21.6 0.8 4.2 4 0 0 4 4 3 1 Midasin AAA lid domain AAA_19 PF13245.6 EKX39168.1 - 0.00026 21.3 0.7 0.79 10.0 0.0 5.1 5 0 0 5 5 4 1 AAA domain Mg_chelatase PF01078.21 EKX39168.1 - 0.0003 20.2 1.8 1.6 8.0 0.0 3.9 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EKX39168.1 - 0.00035 20.9 0.0 8.1 6.9 0.0 4.6 4 0 0 4 4 4 0 RNA helicase Rad17 PF03215.15 EKX39168.1 - 0.00052 20.0 0.3 12 5.7 0.0 5.4 5 0 0 5 5 5 0 Rad17 P-loop domain T2SSE PF00437.20 EKX39168.1 - 0.00056 19.1 0.1 0.35 9.9 0.0 4.0 5 0 0 5 5 5 1 Type II/IV secretion system protein Sigma54_activat PF00158.26 EKX39168.1 - 0.00056 19.6 0.0 0.15 11.8 0.0 3.2 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_29 PF13555.6 EKX39168.1 - 0.00082 19.1 0.1 4 7.2 0.0 3.8 3 0 0 3 3 3 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EKX39168.1 - 0.00082 19.3 2.0 12 5.7 0.0 4.2 4 0 0 4 4 3 0 RsgA GTPase TsaE PF02367.17 EKX39168.1 - 0.00087 19.3 0.3 14 5.7 0.0 4.4 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 EKX39168.1 - 0.00091 19.1 21.5 0.064 13.0 0.0 5.4 5 0 0 5 5 4 1 AAA domain FtsK_SpoIIIE PF01580.18 EKX39168.1 - 0.0013 18.2 0.5 0.2 11.0 0.0 3.7 4 0 0 4 4 4 1 FtsK/SpoIIIE family AAA_25 PF13481.6 EKX39168.1 - 0.0014 18.3 3.9 0.08 12.5 0.0 4.0 4 0 0 4 4 3 1 AAA domain AAA_24 PF13479.6 EKX39168.1 - 0.0015 18.3 2.1 6.3 6.5 0.0 5.2 6 0 0 6 6 4 0 AAA domain AAA_28 PF13521.6 EKX39168.1 - 0.019 15.2 5.5 15 5.8 0.0 5.6 5 0 0 5 5 4 0 AAA domain RuvB_N PF05496.12 EKX39168.1 - 0.076 12.8 0.0 12 5.7 0.0 3.7 4 0 0 4 4 4 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 EKX39168.1 - 0.58 10.7 14.3 6.1 7.4 0.0 5.9 6 0 0 6 6 5 0 ABC transporter DUF853 PF05872.12 EKX39168.1 - 0.87 8.1 15.0 5.4 5.5 0.0 4.1 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF853) Borrelia_P83 PF05262.11 EKX39168.1 - 0.9 8.0 14.5 1.8 6.9 14.5 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein Velvet PF11754.8 EKX39168.1 - 7.2 6.5 7.3 1.1 9.2 1.7 2.1 2 0 0 2 2 2 0 Velvet factor Peptidase_S10 PF00450.22 EKX39169.1 - 9.1e-94 315.2 0.0 1.1e-93 314.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Glyco_transf_20 PF00982.21 EKX39169.1 - 0.22 10.1 0.0 0.31 9.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 20 TPR_1 PF00515.28 EKX39170.1 - 9.5e-14 50.5 0.1 0.00051 19.8 0.0 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX39170.1 - 1.1e-13 50.2 0.8 0.00032 20.6 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX39170.1 - 6.2e-08 32.3 1.1 0.00023 21.1 0.1 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX39170.1 - 4.7e-07 29.4 0.0 0.014 15.0 0.0 3.1 2 1 1 3 3 3 3 TPR repeat ANAPC3 PF12895.7 EKX39170.1 - 2.7e-06 27.5 0.3 0.01 16.0 0.1 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EKX39170.1 - 1e-05 26.1 0.1 0.14 12.8 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX39170.1 - 1.6e-05 25.1 1.7 0.072 13.4 0.6 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX39170.1 - 2.4e-05 24.0 0.1 0.0054 16.7 0.0 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX39170.1 - 5.7e-05 23.6 0.4 0.22 12.5 0.0 2.5 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX39170.1 - 0.0025 18.3 5.1 2.1 9.1 0.0 3.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX39170.1 - 0.0067 16.7 0.1 0.29 11.6 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX39170.1 - 0.0095 16.4 0.0 0.27 11.8 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX39170.1 - 0.024 14.8 0.1 1.8 8.8 0.0 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 EKX39170.1 - 0.044 13.0 0.1 0.066 12.4 0.1 1.4 1 1 0 1 1 1 0 Tetratricopeptide repeat MAS20 PF02064.15 EKX39170.1 - 0.077 13.1 0.4 7.1 6.7 0.1 2.3 1 1 1 2 2 2 0 MAS20 protein import receptor TPR_10 PF13374.6 EKX39170.1 - 0.13 12.2 0.2 26 4.8 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat HemY_N PF07219.13 EKX39170.1 - 0.3 11.3 4.7 7.1 6.9 0.0 3.2 1 1 2 3 3 3 0 HemY protein N-terminus zf-CW PF07496.15 EKX39171.1 - 9.6e-10 38.3 1.4 3.4e-09 36.6 1.4 2.1 1 0 0 1 1 1 1 CW-type Zinc Finger PAS PF00989.25 EKX39174.1 - 2.9e-194 632.9 21.2 4.8e-24 84.5 0.1 10.5 10 0 0 10 10 10 10 PAS fold PAS_4 PF08448.10 EKX39174.1 - 1.9e-117 385.4 0.0 4.2e-12 46.3 0.0 10.7 11 0 0 11 11 11 10 PAS fold PAS_9 PF13426.7 EKX39174.1 - 2.5e-113 371.5 29.3 1.7e-13 50.7 0.4 10.7 10 0 0 10 10 10 10 PAS domain PAS_3 PF08447.12 EKX39174.1 - 9e-71 234.2 0.0 7.8e-08 32.5 0.0 9.2 9 0 0 9 9 9 8 PAS fold Response_reg PF00072.24 EKX39174.1 - 5.5e-56 187.6 5.5 1e-26 93.3 0.1 4.1 4 0 0 4 4 4 3 Response regulator receiver domain PAS_8 PF13188.7 EKX39174.1 - 7.4e-51 169.4 9.6 6.2e-05 22.9 0.0 10.8 10 0 0 10 10 10 8 PAS domain HATPase_c PF02518.26 EKX39174.1 - 4.4e-29 101.3 0.1 2.8e-28 98.7 0.0 2.6 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EKX39174.1 - 4.9e-17 61.7 0.7 2e-16 59.8 0.7 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_10 PF13596.6 EKX39174.1 - 1.1e-16 61.3 11.1 0.16 12.6 0.1 8.8 9 0 0 9 9 9 5 PAS domain PAS_7 PF12860.7 EKX39174.1 - 1.3e-08 35.0 7.2 0.0063 16.7 0.0 8.5 8 1 0 8 8 8 1 PAS fold DUF5588 PF17826.1 EKX39174.1 - 8.9e-06 24.8 2.7 3.6 6.4 0.0 5.3 6 0 0 6 6 6 1 Family of unknown function (DUF5588) PAS_11 PF14598.6 EKX39174.1 - 1.3e-05 25.2 0.2 0.0016 18.6 0.0 4.5 5 0 0 5 5 5 1 PAS domain DUF1824 PF08854.10 EKX39174.1 - 0.007 16.3 4.8 30 4.6 0.0 6.6 7 0 0 7 7 7 0 Domain of unknown function (DUF1824) sCache_3_3 PF17202.4 EKX39174.1 - 1.9 8.9 11.7 53 4.3 0.1 6.4 8 0 0 8 8 7 0 Single cache domain 3 GARS_C PF02843.16 EKX39174.1 - 3.3 8.1 4.8 6.1e+02 0.8 0.0 5.2 6 0 0 6 6 5 0 Phosphoribosylglycinamide synthetase, C domain KH_6 PF15985.5 EKX39175.1 - 6.5e-11 42.4 0.7 2.4e-10 40.6 0.1 2.0 2 0 0 2 2 2 1 KH domain Rrp40_N PF18311.1 EKX39175.1 - 8.1e-05 22.5 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain DUF5010_C PF18099.1 EKX39176.1 - 0.086 13.0 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 DUF5010 C-terminal domain PsbQ PF05757.11 EKX39177.1 - 0.024 14.4 0.2 0.45 10.2 0.0 2.1 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) Lactamase_B PF00753.27 EKX39178.1 - 5.2e-19 69.0 0.0 6.4e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EKX39178.1 - 0.018 14.5 0.1 0.036 13.6 0.1 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain HAGH_C PF16123.5 EKX39178.1 - 0.037 14.5 0.0 0.069 13.7 0.0 1.4 1 0 0 1 1 1 0 Hydroxyacylglutathione hydrolase C-terminus Cupin_8 PF13621.6 EKX39179.1 - 3.9e-07 30.1 0.1 6.3e-07 29.4 0.1 1.3 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EKX39179.1 - 1.9e-05 25.1 0.1 0.00025 21.5 0.0 2.4 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 EKX39179.1 - 0.0097 15.4 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 EKX39179.1 - 0.11 12.2 0.1 0.24 11.2 0.0 1.6 2 0 0 2 2 2 0 Cupin domain Cupin_1 PF00190.22 EKX39179.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Cupin p450 PF00067.22 EKX39181.1 - 6.9e-69 232.8 0.0 1.2e-68 232.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 DnaGprimase_HBD PF16730.5 EKX39181.1 - 0.11 12.6 0.2 0.24 11.5 0.2 1.5 1 0 0 1 1 1 0 DnaG-primase C-terminal, helicase-binding domain CS PF04969.16 EKX39183.1 - 2.6e-09 38.0 1.7 4.1e-09 37.3 1.7 1.2 1 0 0 1 1 1 1 CS domain Siah-Interact_N PF09032.11 EKX39183.1 - 4e-05 23.8 0.0 0.0001 22.5 0.0 1.8 1 0 0 1 1 1 1 Siah interacting protein, N terminal SGS PF05002.15 EKX39183.1 - 0.0034 17.4 0.9 0.0072 16.4 0.9 1.5 1 0 0 1 1 1 1 SGS domain DUF3243 PF11588.8 EKX39183.1 - 0.016 15.5 0.1 0.034 14.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) PRRSV_Env PF02340.15 EKX39183.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 PRRSV putative envelope protein Tctex-1 PF03645.13 EKX39184.1 - 5.9e-27 93.9 0.0 6.6e-27 93.8 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family WD40 PF00400.32 EKX39185.1 - 0.0056 17.5 1.9 0.48 11.4 0.0 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX39185.1 - 0.044 14.1 0.0 2.6 8.4 0.0 3.4 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_7 PF13499.6 EKX39186.1 - 0.00027 21.3 0.2 0.0008 19.8 0.0 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 EKX39186.1 - 0.0026 17.6 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX39186.1 - 0.014 14.9 0.4 0.028 13.9 0.4 1.5 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 EKX39186.1 - 0.023 14.2 0.1 0.047 13.3 0.1 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 EKX39186.1 - 0.027 14.4 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain SPRY PF00622.28 EKX39187.1 - 2e-18 66.7 0.1 3.4e-14 53.0 0.1 2.4 2 0 0 2 2 2 2 SPRY domain LexA_DNA_bind PF01726.16 EKX39187.1 - 0.087 12.6 0.0 0.3 10.9 0.0 1.9 1 0 0 1 1 1 0 LexA DNA binding domain MADF_DNA_bdg PF10545.9 EKX39187.1 - 0.26 11.6 1.2 0.84 10.0 0.1 2.3 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Sel1 PF08238.12 EKX39188.1 - 9.1e-40 134.2 24.2 4.2e-09 36.8 0.3 6.5 6 0 0 6 6 6 5 Sel1 repeat SAM_1 PF00536.30 EKX39188.1 - 1.6e-10 41.3 0.4 3.3e-10 40.2 0.4 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EKX39188.1 - 4.8e-08 33.0 0.2 1e-07 32.0 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TPR_1 PF00515.28 EKX39188.1 - 7.1e-07 28.8 36.4 7.3e-05 22.4 0.1 7.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX39188.1 - 1.7e-06 27.7 31.1 0.0012 18.8 0.0 8.4 8 1 1 9 9 8 3 Tetratricopeptide repeat SAM_PNT PF02198.16 EKX39188.1 - 0.00014 21.8 0.0 0.00046 20.1 0.0 1.8 2 0 0 2 2 1 1 Sterile alpha motif (SAM)/Pointed domain TPR_17 PF13431.6 EKX39188.1 - 0.00027 21.1 3.5 0.98 10.0 0.2 5.7 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX39188.1 - 0.00045 20.2 20.1 0.019 15.1 0.0 6.5 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX39188.1 - 0.00053 20.4 0.0 0.00053 20.4 0.0 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX39188.1 - 0.00077 19.7 8.2 0.067 13.5 0.1 4.4 3 1 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX39188.1 - 0.002 18.2 1.5 0.22 11.6 0.3 2.9 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat MIB_HERC2 PF06701.13 EKX39188.1 - 0.013 15.7 0.8 0.037 14.3 0.3 2.1 2 0 0 2 2 1 0 Mib_herc2 TPR_7 PF13176.6 EKX39188.1 - 0.65 10.1 4.8 18 5.7 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX39188.1 - 0.91 10.5 0.0 0.91 10.5 0.0 5.3 5 2 1 6 6 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EKX39188.1 - 2.8 7.7 20.2 0.19 11.5 0.2 5.2 5 0 0 5 5 5 0 TPR repeat ANAPC3 PF12895.7 EKX39188.1 - 7.8 6.8 10.1 1.4 9.2 1.5 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 JmjC PF02373.22 EKX39189.1 - 2e-12 47.5 0.1 6.7e-12 45.9 0.1 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 EKX39189.1 - 1.2e-08 35.0 0.0 3.6e-08 33.4 0.0 1.9 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EKX39189.1 - 1.2e-05 24.9 0.5 0.00011 21.7 0.0 2.1 2 0 0 2 2 2 1 Cupin superfamily protein 2OG-FeII_Oxy_5 PF13759.6 EKX39189.1 - 0.0025 18.2 0.1 0.0046 17.4 0.1 1.4 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Cupin_2 PF07883.11 EKX39189.1 - 0.014 15.1 0.1 0.078 12.7 0.0 2.0 2 0 0 2 2 2 0 Cupin domain Cupin_1 PF00190.22 EKX39189.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Cupin Jacalin PF01419.17 EKX39190.1 - 0.017 15.0 1.2 0.12 12.3 0.1 2.5 3 0 0 3 3 3 0 Jacalin-like lectin domain zf-CCCH_6 PF18585.1 EKX39190.1 - 1.5 8.7 6.1 25 4.9 0.3 3.6 3 0 0 3 3 3 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 WD40 PF00400.32 EKX39191.1 - 0.00013 22.7 3.3 0.1 13.5 0.0 4.4 4 1 1 5 5 5 2 WD domain, G-beta repeat EF-hand_6 PF13405.6 EKX39192.1 - 3.5e-13 48.3 7.9 0.00072 19.3 0.1 3.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 EKX39192.1 - 2.7e-12 45.3 6.9 0.0014 18.0 0.1 3.9 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 EKX39192.1 - 2.2e-11 44.0 4.4 2.9e-05 24.4 0.9 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX39192.1 - 4.4e-06 25.9 7.0 0.013 15.0 0.5 3.8 3 1 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 EKX39192.1 - 5.4e-05 23.5 1.4 0.001 19.3 0.8 2.3 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 EKX39192.1 - 0.00033 20.4 2.4 0.061 13.2 0.0 3.4 2 1 2 4 4 4 1 EF-hand domain pair Dockerin_1 PF00404.18 EKX39192.1 - 0.0019 18.3 2.0 0.013 15.6 2.0 2.4 1 1 0 1 1 1 1 Dockerin type I domain ABC2_membrane PF01061.24 EKX39193.1 - 5.5e-39 133.8 15.9 7.7e-39 133.3 15.9 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EKX39193.1 - 4.8e-25 88.7 0.0 8.4e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EKX39193.1 - 1.8e-05 24.7 0.7 0.016 15.0 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EKX39193.1 - 2.1e-05 24.1 0.1 0.0011 18.5 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EKX39193.1 - 4.3e-05 23.5 0.1 9.3e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 EKX39193.1 - 0.00051 19.7 0.5 0.00086 18.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 EKX39193.1 - 0.00051 19.2 11.9 0.00072 18.8 11.9 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_29 PF13555.6 EKX39193.1 - 0.0017 18.1 0.6 0.004 16.9 0.6 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EKX39193.1 - 0.0031 18.0 0.1 0.0056 17.2 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_13 PF13166.6 EKX39193.1 - 0.01 14.6 0.0 0.96 8.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EKX39193.1 - 0.011 16.1 0.0 0.047 14.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EKX39193.1 - 0.017 15.5 0.4 0.11 12.9 0.4 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EKX39193.1 - 0.026 14.4 0.1 0.064 13.2 0.1 1.7 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 EKX39193.1 - 0.031 14.3 0.1 0.073 13.2 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 EKX39193.1 - 0.032 14.6 0.4 0.1 12.9 0.2 2.0 2 1 0 2 2 2 0 AAA ATPase domain cobW PF02492.19 EKX39193.1 - 0.048 13.2 0.2 0.11 12.1 0.2 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 EKX39193.1 - 0.16 12.2 1.4 0.32 11.2 1.4 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EKX39193.1 - 0.17 11.8 0.3 5 7.0 0.1 2.3 2 0 0 2 2 2 0 NTPase SbcCD_C PF13558.6 EKX39193.1 - 0.18 12.1 0.2 1.4 9.2 0.0 2.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 EKX39193.1 - 0.37 10.5 2.2 0.61 9.8 2.2 1.4 1 1 0 1 1 1 0 AAA domain SLC12 PF03522.15 EKX39194.1 - 0.17 10.9 1.6 0.22 10.5 1.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF4551 PF15087.6 EKX39194.1 - 6.3 5.5 9.1 8.4 5.1 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Retrotrans_gag PF03732.17 EKX39195.1 - 0.0016 18.7 0.1 0.0032 17.7 0.1 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein TMEM237 PF15383.6 EKX39197.1 - 1.2e-07 31.2 1.1 3.3e-07 29.7 1.1 1.7 1 0 0 1 1 1 1 Transmembrane protein 237 Macoilin PF09726.9 EKX39197.1 - 3.3 6.1 9.5 4.1 5.9 9.5 1.1 1 0 0 1 1 1 0 Macoilin family CGI-121 PF08617.10 EKX39198.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Kinase binding protein CGI-121 Gly_transf_sug PF04488.15 EKX39199.1 - 5.4e-10 39.8 1.6 1.5e-08 35.1 0.5 3.1 3 0 0 3 3 3 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EKX39199.1 - 1.1e-06 28.3 0.4 2.4e-06 27.2 0.4 1.5 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 EKX39199.1 - 0.00085 18.7 3.2 0.17 11.1 0.2 2.2 1 1 1 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain Sugar_tr PF00083.24 EKX39200.1 - 3.8e-78 263.4 13.1 4.4e-78 263.1 13.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EKX39200.1 - 2.5e-22 79.3 26.9 4.4e-22 78.5 26.9 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3267 PF11667.8 EKX39200.1 - 5.8 7.3 8.9 0.54 10.6 1.5 2.9 2 1 1 3 3 3 0 Putative zincin peptidase Glyco_hydro_38N PF01074.22 EKX39201.1 - 8.9e-86 287.8 5.1 1.4e-85 287.2 5.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EKX39201.1 - 8.9e-40 137.0 0.0 2.1e-39 135.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EKX39201.1 - 1.8e-18 66.4 0.1 3.9e-18 65.4 0.1 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 EKX39201.1 - 0.077 13.1 0.0 1.1 9.4 0.0 2.7 2 1 0 2 2 2 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Pkinase PF00069.25 EKX39202.1 - 1e-64 218.5 0.0 1.8e-64 217.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX39202.1 - 4.4e-45 154.0 0.0 6.3e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX39202.1 - 5.9e-07 29.1 0.0 9.7e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EKX39202.1 - 6.8e-05 21.8 0.6 0.00033 19.5 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 EKX39202.1 - 0.00012 21.2 0.1 0.00026 20.1 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain DUF3552 PF12072.8 EKX39202.1 - 0.012 15.0 27.5 0.073 12.5 10.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3552) Golgin_A5 PF09787.9 EKX39202.1 - 0.051 13.0 11.9 0.1 12.1 11.9 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 His_Phos_1 PF00300.22 EKX39202.1 - 0.14 11.8 2.6 0.27 10.9 2.6 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Exonuc_VII_L PF02601.15 EKX39202.1 - 0.32 10.5 7.5 0.52 9.8 7.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 EKX39202.1 - 1.7 7.6 11.4 9.8 5.1 9.6 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 E2F_CC-MB PF16421.5 EKX39202.1 - 2.4 8.6 8.1 0.61 10.5 0.8 3.0 2 1 1 3 3 3 0 E2F transcription factor CC-MB domain DUF4200 PF13863.6 EKX39202.1 - 4.1 7.8 25.8 0.68 10.3 10.3 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) V_ATPase_I PF01496.19 EKX39202.1 - 5.5 4.8 10.7 7.5 4.3 10.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 EKX39202.1 - 6 6.1 9.1 9 5.5 9.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM76 PF16046.5 EKX39202.1 - 6.8 6.0 17.1 43 3.3 16.1 2.6 1 1 1 2 2 2 0 FAM76 protein Methyltr_RsmB-F PF01189.17 EKX39203.1 - 8.5e-15 54.9 0.0 1.1e-13 51.2 0.0 2.4 2 1 0 2 2 2 1 16S rRNA methyltransferase RsmB/F CobN-Mg_chel PF02514.16 EKX39204.1 - 0 1100.9 0.0 0 1098.5 0.0 1.8 1 1 0 1 1 1 1 CobN/Magnesium Chelatase DUF3479 PF11965.8 EKX39204.1 - 2.5e-49 167.5 0.8 5.5e-49 166.4 0.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3479) RWP-RK PF02042.15 EKX39205.1 - 4.9e-21 74.4 0.0 5.8e-21 74.2 0.0 1.0 1 0 0 1 1 1 1 RWP-RK domain EF-hand_1 PF00036.32 EKX39206.1 - 6e-09 34.8 1.3 0.00074 18.9 0.1 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX39206.1 - 1.4e-07 30.9 0.2 0.0002 21.1 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EKX39206.1 - 3.4e-06 27.4 0.2 1e-05 25.8 0.2 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX39206.1 - 2.6e-05 23.5 0.3 0.0053 16.2 0.1 2.9 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 EKX39206.1 - 0.032 14.6 0.0 0.072 13.4 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.6 EKX39206.1 - 0.035 13.9 1.3 1.2 9.0 0.1 3.3 3 0 0 3 3 3 0 EF-hand domain pair DUF244 PF03112.14 EKX39206.1 - 0.11 12.3 0.2 0.2 11.5 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF DUF4762 PF15959.5 EKX39206.1 - 1.9 8.6 3.3 1.2 9.2 0.2 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4762) Arm PF00514.23 EKX39207.1 - 1.7e-05 24.7 0.2 0.002 18.1 0.0 3.0 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EKX39207.1 - 0.00082 19.4 0.6 0.0015 18.5 0.6 1.6 1 1 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Imp-YgjV PF10688.9 EKX39207.1 - 0.21 11.4 0.0 0.25 11.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial inner membrane protein Pkinase PF00069.25 EKX39208.1 - 6.7e-34 117.5 0.0 7.9e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX39208.1 - 7.2e-28 97.6 0.0 7.9e-28 97.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX39208.1 - 5.5e-06 25.4 0.0 7.8e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EKX39208.1 - 0.012 15.0 0.0 0.014 14.7 0.0 1.3 1 1 0 1 1 1 0 Kinase-like RIO1 PF01163.22 EKX39208.1 - 0.046 13.3 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EKX39208.1 - 0.12 12.3 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family SAM_1 PF00536.30 EKX39209.1 - 8e-09 35.8 0.1 1.4e-08 35.0 0.1 1.4 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EKX39209.1 - 1.2e-07 31.7 0.0 1.9e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 EKX39209.1 - 0.009 16.0 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain RestrictionSfiI PF11487.8 EKX39209.1 - 0.014 15.3 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Type II restriction enzyme SfiI SAM_4 PF18017.1 EKX39209.1 - 0.09 12.8 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Mito_carr PF00153.27 EKX39210.1 - 2.8e-58 193.9 2.0 4.4e-20 71.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SGT1 PF07093.11 EKX39212.1 - 1.3e-112 377.2 0.0 4e-111 372.3 0.0 2.0 1 1 0 1 1 1 1 SGT1 protein TetR_C_20 PF17925.1 EKX39212.1 - 0.099 13.0 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Sel1 PF08238.12 EKX39213.1 - 4.5e-19 68.5 0.4 1.4e-09 38.3 0.1 2.7 2 0 0 2 2 2 2 Sel1 repeat PUB PF09409.10 EKX39213.1 - 3.5e-05 23.6 0.0 8.5e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 PUB domain OCRE PF17780.1 EKX39213.1 - 0.0027 17.7 0.0 0.0053 16.8 0.0 1.4 1 0 0 1 1 1 1 OCRE domain Bestrophin PF01062.21 EKX39214.1 - 3.2e-39 135.1 2.1 4.1e-39 134.7 2.1 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF1699 PF08004.11 EKX39214.1 - 0.018 14.7 0.1 0.049 13.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) TBK1_ULD PF18396.1 EKX39216.1 - 0.0024 17.8 0.0 0.008 16.1 0.0 2.1 2 1 0 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain BAG PF02179.16 EKX39216.1 - 0.15 12.5 2.1 0.36 11.3 1.5 2.0 2 1 0 2 2 2 0 BAG domain LysM PF01476.20 EKX39218.1 - 0.076 13.1 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 LysM domain zinc_ribbon_16 PF17034.5 EKX39221.1 - 1.7e-14 54.1 17.0 4e-13 49.7 17.0 2.6 1 1 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 EKX39221.1 - 0.00015 21.3 6.9 0.00015 21.3 6.9 2.7 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type Ank_2 PF12796.7 EKX39222.1 - 4.6e-30 104.0 0.1 1.5e-11 44.7 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX39222.1 - 5.7e-28 96.9 6.0 8e-10 39.1 0.1 4.9 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX39222.1 - 7.9e-26 87.3 1.6 2.6e-05 24.3 0.0 6.8 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.6 EKX39222.1 - 2.9e-21 75.3 7.1 3.4e-07 30.4 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EKX39222.1 - 1.7e-17 62.9 5.3 1.9e-05 24.9 0.0 6.2 6 1 0 6 6 6 3 Ankyrin repeat Prenyltransf PF01255.19 EKX39223.1 - 2.6e-65 220.1 0.0 3.3e-65 219.7 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase CS PF04969.16 EKX39224.1 - 5.7e-05 24.1 0.1 9.5e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 CS domain ELFV_dehydrog PF00208.21 EKX39225.1 - 1.8e-13 50.8 5.8 9.8e-09 35.3 0.2 2.6 1 1 2 3 3 3 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EKX39225.1 - 6.5e-07 29.3 0.1 1.4e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.19 EKX39225.1 - 0.0016 17.9 0.1 0.0039 16.6 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EKX39225.1 - 0.0018 18.6 0.6 0.0055 17.1 0.1 2.1 2 1 0 2 2 2 1 Putative NAD(P)-binding AdoHcyase_NAD PF00670.21 EKX39225.1 - 0.022 14.8 1.0 0.061 13.4 1.0 1.8 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ThiF PF00899.21 EKX39225.1 - 0.024 14.0 0.3 0.042 13.2 0.3 1.4 1 0 0 1 1 1 0 ThiF family TrkA_N PF02254.18 EKX39225.1 - 0.029 14.6 0.1 0.08 13.2 0.1 1.8 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 EKX39225.1 - 0.067 12.8 0.3 0.12 12.0 0.3 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SASP PF00269.20 EKX39225.1 - 0.13 12.3 0.1 5.7 7.0 0.1 2.5 2 0 0 2 2 2 0 Small, acid-soluble spore proteins, alpha/beta type Shikimate_DH PF01488.20 EKX39225.1 - 0.15 12.1 0.1 0.38 10.8 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Homeobox_KN PF05920.11 EKX39226.1 - 4.5e-15 55.3 0.0 5.8e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EKX39226.1 - 9.9e-09 34.9 0.0 1.3e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 EKX39226.1 - 0.0055 16.1 0.8 0.11 12.0 0.1 2.0 1 1 1 2 2 2 1 Homeodomain leucine-zipper encoding, Homez HTH_ABP1_N PF18107.1 EKX39226.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.5 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain DUF2961 PF11175.8 EKX39227.1 - 3.8e-33 115.1 0.0 3.4e-32 112.0 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2961) CNP_C_terminal PF17839.1 EKX39227.1 - 0.13 13.0 0.3 0.3 11.8 0.3 1.5 1 0 0 1 1 1 0 C-terminal domain of cyclic nucleotide phosphodiesterase TAL_FSA PF00923.19 EKX39229.1 - 1.5e-101 339.5 2.6 1.7e-101 339.3 2.6 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase PUL PF08324.11 EKX39229.1 - 0.0082 15.4 0.2 0.013 14.8 0.2 1.3 1 0 0 1 1 1 1 PUL domain Thioredoxin_6 PF13848.6 EKX39230.1 - 9e-06 25.7 0.1 1.5e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain TBP PF00352.21 EKX39231.1 - 5.7e-10 39.0 0.0 0.00028 20.8 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) Acid_PPase PF12689.7 EKX39232.1 - 5.6e-54 182.5 0.0 6.4e-54 182.3 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Tcp10_C PF07202.13 EKX39232.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 T-complex protein 10 C-terminus Pkinase PF00069.25 EKX39233.1 - 7.1e-66 222.3 0.1 1.4e-65 221.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX39233.1 - 3.7e-36 124.8 0.0 6e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 EKX39233.1 - 6.9e-05 23.2 0.9 6.9e-05 23.2 0.9 3.0 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX39233.1 - 0.00011 21.4 0.3 0.00083 18.7 0.0 2.6 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 EKX39233.1 - 0.00018 20.9 0.0 0.00054 19.3 0.0 1.9 1 0 0 1 1 1 1 EF hand Kinase-like PF14531.6 EKX39233.1 - 0.00037 19.9 0.0 0.0011 18.4 0.0 1.7 1 1 0 1 1 1 1 Kinase-like EF-hand_8 PF13833.6 EKX39233.1 - 0.00048 19.9 0.4 0.0066 16.3 0.0 2.7 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX39233.1 - 0.0036 17.1 0.7 0.14 12.2 0.0 3.3 3 1 1 4 4 4 1 EF-hand domain Kdo PF06293.14 EKX39233.1 - 0.011 15.1 0.0 0.025 13.9 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EKX39233.1 - 0.035 12.9 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase BAR_3 PF16746.5 EKX39233.1 - 0.036 13.8 1.9 0.29 10.8 0.2 2.5 2 0 0 2 2 2 0 BAR domain of APPL family Exog_C PF18026.1 EKX39234.1 - 6.4 6.9 8.6 0.55 10.3 0.6 3.1 4 0 0 4 4 4 0 Endo/exonuclease (EXOG) C-terminal domain Ribosomal_S24e PF01282.19 EKX39235.1 - 1.5e-27 95.3 0.0 3e-27 94.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S24e Macro PF01661.21 EKX39235.1 - 0.13 12.3 1.3 0.65 10.1 0.6 2.0 2 0 0 2 2 2 0 Macro domain Epimerase PF01370.21 EKX39237.1 - 9.4e-13 48.2 0.0 1.3e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EKX39237.1 - 7.9e-10 38.3 0.0 1.2e-09 37.7 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EKX39237.1 - 7.2e-06 25.3 0.0 4.9e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EKX39237.1 - 0.00026 20.5 0.0 0.0005 19.6 0.0 1.6 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EKX39237.1 - 0.0024 16.9 0.0 0.0035 16.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Gly_transf_sug PF04488.15 EKX39239.1 - 9.4e-08 32.6 0.0 1.9e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EKX39239.1 - 0.00019 20.9 0.0 0.00019 20.9 0.0 2.2 2 0 0 2 2 1 1 Capsular polysaccharide synthesis protein BUD22 PF09073.10 EKX39239.1 - 0.00033 20.1 13.9 0.00041 19.8 13.9 1.1 1 0 0 1 1 1 1 BUD22 DDHD PF02862.17 EKX39239.1 - 0.0011 19.2 2.3 0.0015 18.8 2.3 1.1 1 0 0 1 1 1 1 DDHD domain TcdA_TcdB PF12919.7 EKX39239.1 - 0.0016 17.8 0.0 0.0016 17.8 0.0 1.9 2 0 0 2 2 1 1 TcdA/TcdB catalytic glycosyltransferase domain Peptidase_S64 PF08192.11 EKX39239.1 - 0.031 12.8 6.6 0.038 12.5 6.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 DNA_pol_phi PF04931.13 EKX39239.1 - 0.036 12.2 27.5 0.046 11.8 27.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Rrn6 PF10214.9 EKX39239.1 - 0.055 12.0 6.7 0.066 11.7 6.7 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Mpp10 PF04006.12 EKX39239.1 - 0.056 11.9 25.6 0.072 11.5 25.6 1.0 1 0 0 1 1 1 0 Mpp10 protein CCDC53 PF10152.9 EKX39239.1 - 0.11 12.9 13.7 0.17 12.3 13.7 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF4471 PF14740.6 EKX39239.1 - 0.12 11.5 5.5 0.16 11.2 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) DUF2828 PF11443.8 EKX39239.1 - 0.14 10.3 10.4 0.18 9.9 10.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) GREB1 PF15782.5 EKX39239.1 - 0.16 9.1 5.0 0.2 8.7 5.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer FmiP_Thoc5 PF09766.9 EKX39239.1 - 0.17 11.1 18.9 0.24 10.7 18.9 1.1 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 SpoIIP PF07454.11 EKX39239.1 - 0.21 11.0 17.4 0.3 10.5 17.4 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) NPR3 PF03666.13 EKX39239.1 - 0.24 10.1 14.8 0.33 9.7 14.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF5308 PF17233.2 EKX39239.1 - 0.25 11.6 4.4 0.36 11.0 4.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) CDC45 PF02724.14 EKX39239.1 - 0.29 9.4 21.0 0.4 8.9 21.0 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 EKX39239.1 - 0.33 10.3 24.3 0.44 9.9 24.3 1.1 1 0 0 1 1 1 0 SDA1 AAR2 PF05282.11 EKX39239.1 - 0.35 10.2 6.2 0.51 9.7 6.2 1.3 1 0 0 1 1 1 0 AAR2 protein DUF2151 PF10221.9 EKX39239.1 - 0.54 8.8 10.7 0.65 8.5 10.7 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator eIF3_subunit PF08597.10 EKX39239.1 - 0.62 9.9 24.8 0.83 9.5 24.8 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit NARP1 PF12569.8 EKX39239.1 - 0.63 8.9 17.6 0.87 8.4 17.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Zip PF02535.22 EKX39239.1 - 0.64 9.2 8.8 1.1 8.4 8.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter FAM60A PF15396.6 EKX39239.1 - 0.7 9.9 10.4 1 9.3 10.4 1.2 1 0 0 1 1 1 0 Protein Family FAM60A FancD2 PF14631.6 EKX39239.1 - 0.89 6.9 13.4 1.2 6.5 13.4 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease JCAD PF15351.6 EKX39239.1 - 0.91 7.2 13.5 1.1 6.9 13.5 1.0 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease Otopetrin PF03189.13 EKX39239.1 - 0.95 8.2 2.2 1.4 7.7 2.2 1.2 1 0 0 1 1 1 0 Otopetrin Raftlin PF15250.6 EKX39239.1 - 0.97 8.1 10.2 1.2 7.8 10.2 1.1 1 0 0 1 1 1 0 Raftlin AAA_11 PF13086.6 EKX39239.1 - 1 9.1 11.6 1.4 8.6 11.6 1.1 1 0 0 1 1 1 0 AAA domain DUF913 PF06025.12 EKX39239.1 - 1.2 8.1 12.1 1.6 7.6 12.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 EKX39239.1 - 1.6 7.4 20.7 0.16 10.7 15.8 1.7 2 0 0 2 2 2 0 Presenilin RP-C_C PF11800.8 EKX39239.1 - 1.9 8.5 12.5 2.6 8.1 12.5 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF5523 PF17661.1 EKX39239.1 - 2.8 7.6 26.0 4 7.1 26.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DUF4045 PF13254.6 EKX39239.1 - 2.9 7.4 13.2 4 7.0 13.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SLC12 PF03522.15 EKX39239.1 - 3.1 6.7 13.6 3.9 6.4 13.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF1754 PF08555.10 EKX39239.1 - 4.4 8.2 30.0 6.7 7.6 30.0 1.1 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Pex14_N PF04695.13 EKX39239.1 - 4.8 7.8 12.3 7.6 7.2 12.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ALMT PF11744.8 EKX39239.1 - 5.2 5.8 10.3 7.4 5.3 10.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2370 PF10176.9 EKX39239.1 - 5.3 6.6 5.9 7.7 6.1 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) ASC PF00858.24 EKX39239.1 - 5.5 5.8 5.9 8.6 5.2 5.9 1.2 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel DUF4628 PF15429.6 EKX39239.1 - 6.3 6.4 13.4 9.2 5.8 13.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) SAPS PF04499.15 EKX39239.1 - 6.6 5.4 14.8 8.9 5.0 14.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Methyltransf_25 PF13649.6 EKX39240.1 - 4.7e-06 27.2 0.0 0.00026 21.7 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX39240.1 - 6.8e-06 26.7 0.0 3.9e-05 24.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX39240.1 - 0.008 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EKX39240.1 - 0.013 15.1 0.0 0.14 11.8 0.0 2.1 2 0 0 2 2 2 0 Nodulation protein S (NodS) Methyltransf_31 PF13847.6 EKX39240.1 - 0.021 14.6 0.0 3.4 7.4 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain zf-RanBP PF00641.18 EKX39242.1 - 0.00032 19.9 2.5 0.0007 18.9 2.5 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF4672 PF15716.5 EKX39242.1 - 0.32 10.6 14.7 0.47 10.1 14.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4672) DUF4775 PF16001.5 EKX39242.1 - 1.9 7.8 31.4 2.3 7.6 31.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) Pkinase PF00069.25 EKX39244.1 - 8e-38 130.3 0.0 1.5e-36 126.1 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX39244.1 - 2.3e-10 40.2 0.0 7.4e-08 32.0 0.0 2.3 1 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EKX39244.1 - 0.0024 17.9 0.0 0.0055 16.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EKX39244.1 - 0.0088 15.7 0.1 0.025 14.2 0.0 1.7 1 1 1 2 2 2 1 Choline/ethanolamine kinase DUF948 PF06103.11 EKX39245.1 - 0.011 16.0 0.5 0.032 14.5 0.2 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Lge1 PF11488.8 EKX39245.1 - 5.7 7.2 9.3 0.86 9.8 0.5 2.3 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 Pkinase PF00069.25 EKX39246.1 - 1.1e-13 51.2 0.0 5.4e-13 48.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX39246.1 - 9.2e-13 48.1 0.9 2.2e-11 43.5 0.4 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Ephrin_rec_like PF07699.13 EKX39250.1 - 5.7e-19 67.6 42.3 1.1e-09 37.9 9.4 4.2 2 1 1 3 3 3 3 Putative ephrin-receptor like Kelch_4 PF13418.6 EKX39250.1 - 1.9e-06 27.8 1.9 2.8e-05 24.0 0.2 3.6 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_5 PF13854.6 EKX39250.1 - 1.2e-05 25.2 8.0 0.00022 21.1 0.3 5.1 6 0 0 6 6 6 1 Kelch motif Kelch_3 PF13415.6 EKX39250.1 - 3.3e-05 24.0 10.1 0.003 17.8 0.3 4.6 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.15 EKX39250.1 - 0.00024 20.9 5.5 2.2 8.4 0.0 6.0 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.6 EKX39250.1 - 0.00033 20.8 0.5 0.1 12.9 0.1 4.4 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.25 EKX39250.1 - 0.033 13.8 2.7 0.98 9.1 0.1 4.0 4 0 0 4 4 4 0 Kelch motif LRR_10 PF18805.1 EKX39250.1 - 0.22 11.2 1.7 22 4.8 0.0 3.5 3 0 0 3 3 3 0 Leucine-rich repeat PDZ PF00595.24 EKX39251.1 - 3.5e-10 40.1 0.5 5e-10 39.6 0.5 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX39251.1 - 1.1e-09 38.5 0.8 1.6e-09 38.0 0.8 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX39251.1 - 8.9e-09 35.1 0.1 1.8e-08 34.1 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX39251.1 - 0.00063 19.7 0.1 0.0014 18.5 0.1 1.6 1 0 0 1 1 1 1 Tricorn protease PDZ domain SH3_2 PF07653.17 EKX39253.1 - 0.0099 15.5 0.7 0.064 12.9 0.2 2.2 2 1 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 EKX39253.1 - 0.038 13.6 0.1 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 SH3 domain AAA_lid_9 PF17871.1 EKX39254.1 - 3.6e-32 110.4 0.3 3.6e-32 110.4 0.3 2.6 4 0 0 4 4 1 1 AAA lid domain AAA_2 PF07724.14 EKX39254.1 - 1.3e-19 70.9 0.3 3e-16 60.0 0.1 3.7 2 1 1 3 3 3 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 EKX39254.1 - 2.6e-17 62.6 0.1 1.9e-16 59.9 0.1 2.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EKX39254.1 - 3.3e-16 59.9 0.1 1.3e-13 51.5 0.0 3.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX39254.1 - 1.1e-10 42.1 9.2 2.7e-07 31.1 0.1 4.4 3 1 1 4 4 4 2 AAA ATPase domain ATPase_2 PF01637.18 EKX39254.1 - 1.6e-06 28.2 2.1 0.0045 16.9 0.2 3.7 2 2 0 2 2 2 1 ATPase domain predominantly from Archaea TniB PF05621.11 EKX39254.1 - 6.8e-06 25.6 0.1 0.0056 16.1 0.0 3.5 2 1 0 2 2 2 1 Bacterial TniB protein Clp_N PF02861.20 EKX39254.1 - 7.2e-06 26.0 0.0 4.1e-05 23.6 0.0 2.5 2 0 0 2 2 2 1 Clp amino terminal domain, pathogenicity island component AAA_22 PF13401.6 EKX39254.1 - 4.5e-05 23.8 4.8 0.0054 17.0 0.1 4.6 3 1 0 4 4 4 1 AAA domain AAA_5 PF07728.14 EKX39254.1 - 5.6e-05 23.2 0.2 0.049 13.6 0.1 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EKX39254.1 - 7.8e-05 22.3 0.0 0.0086 15.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 EKX39254.1 - 0.00015 22.3 0.3 1.2 9.7 0.0 3.2 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.17 EKX39254.1 - 0.00098 18.9 0.0 0.34 10.6 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein RsgA_GTPase PF03193.16 EKX39254.1 - 0.0019 18.2 0.0 1.9 8.4 0.0 3.0 3 0 0 3 3 2 1 RsgA GTPase RuvB_N PF05496.12 EKX39254.1 - 0.0024 17.6 0.2 23 4.7 0.0 3.8 4 0 0 4 4 3 0 Holliday junction DNA helicase RuvB P-loop domain Roc PF08477.13 EKX39254.1 - 0.0035 17.6 0.1 0.96 9.7 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 EKX39254.1 - 0.0096 16.0 0.1 0.039 14.0 0.0 2.1 2 0 0 2 2 1 1 AAA domain NACHT PF05729.12 EKX39254.1 - 0.01 15.8 0.1 0.11 12.5 0.0 2.5 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 EKX39254.1 - 0.014 15.1 0.0 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 EKX39254.1 - 0.016 15.2 0.0 0.42 10.6 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EKX39254.1 - 0.018 15.4 0.3 1.7 9.1 0.0 2.9 2 1 1 3 3 3 0 RNA helicase AAA_25 PF13481.6 EKX39254.1 - 0.024 14.2 0.1 10 5.6 0.0 4.0 3 1 0 4 4 4 0 AAA domain AAA_30 PF13604.6 EKX39254.1 - 0.037 13.7 0.1 2.2 8.0 0.0 2.9 2 1 0 2 2 2 0 AAA domain DUF1640 PF07798.11 EKX39254.1 - 0.043 13.9 2.9 0.044 13.8 1.1 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF1640) AAA_33 PF13671.6 EKX39254.1 - 0.052 13.7 0.0 1.1 9.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EKX39254.1 - 0.1 13.1 0.0 22 5.5 0.0 2.8 2 0 0 2 2 2 0 ABC transporter NHase_alpha PF02979.16 EKX39254.1 - 0.17 11.2 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 Nitrile hydratase, alpha chain Macoilin PF09726.9 EKX39254.1 - 0.59 8.6 2.7 0.93 8.0 2.7 1.2 1 0 0 1 1 1 0 Macoilin family Mei5 PF10376.9 EKX39254.1 - 1.4 8.7 6.7 0.3 10.9 1.1 2.5 3 0 0 3 3 2 0 Double-strand recombination repair protein Epimerase PF01370.21 EKX39255.1 - 1.2e-50 172.2 0.0 1.7e-50 171.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EKX39255.1 - 1.3e-14 54.4 0.1 3e-14 53.1 0.0 1.5 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EKX39255.1 - 4e-08 32.7 0.5 0.00012 21.4 0.0 3.2 2 1 1 3 3 3 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EKX39255.1 - 1.1e-05 24.7 0.0 1.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EKX39255.1 - 0.00017 20.7 0.2 0.0015 17.6 0.2 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EKX39255.1 - 0.0002 20.6 0.2 0.00062 19.0 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein SAM_1 PF00536.30 EKX39257.1 - 2.1e-06 28.1 0.0 4.2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EKX39257.1 - 0.0009 19.3 0.1 0.0014 18.7 0.1 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Nodulin_late PF07127.11 EKX39258.1 - 0.014 15.7 0.1 0.014 15.7 0.1 3.4 4 0 0 4 4 4 0 Late nodulin protein TTL PF03133.15 EKX39259.1 - 1.4e-62 211.5 0.0 1.6e-62 211.3 0.0 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EKX39259.1 - 2e-09 37.1 0.9 0.00021 20.7 0.0 3.2 2 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EKX39259.1 - 5.2e-07 29.2 0.0 0.015 14.6 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EKX39259.1 - 0.00012 22.2 0.0 0.048 13.7 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp domain Marek_A PF02124.15 EKX39260.1 - 0.0087 15.9 0.5 0.016 15.1 0.5 1.4 1 0 0 1 1 1 1 Marek's disease glycoprotein A Nodulin_late PF07127.11 EKX39260.1 - 0.31 11.4 0.0 0.31 11.4 0.0 4.1 4 0 0 4 4 4 0 Late nodulin protein Inhibitor_I53 PF11714.8 EKX39260.1 - 0.37 11.0 1.7 0.39 10.9 0.1 2.0 2 0 0 2 2 2 0 Thrombin inhibitor Madanin Meckelin PF09773.9 EKX39260.1 - 2 6.4 9.2 0.087 10.9 0.3 2.0 2 0 0 2 2 2 0 Meckelin (Transmembrane protein 67) Pro_isomerase PF00160.21 EKX39262.1 - 2.6e-50 170.8 0.0 3.1e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNase_PH PF01138.21 EKX39263.1 - 1.2e-21 77.6 0.7 3.7e-21 76.0 0.3 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EKX39263.1 - 0.0014 18.6 0.0 0.0038 17.2 0.0 1.8 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Marek_A PF02124.15 EKX39264.1 - 0.0086 15.9 0.4 0.015 15.1 0.4 1.4 1 0 0 1 1 1 1 Marek's disease glycoprotein A Nodulin_late PF07127.11 EKX39264.1 - 0.23 11.8 0.0 0.23 11.8 0.0 4.1 4 0 0 4 4 4 0 Late nodulin protein Inhibitor_I53 PF11714.8 EKX39264.1 - 0.39 11.0 1.7 0.39 10.9 0.1 2.0 2 0 0 2 2 2 0 Thrombin inhibitor Madanin Meckelin PF09773.9 EKX39264.1 - 1.3 7.0 9.1 0.062 11.4 0.3 2.0 2 0 0 2 2 2 0 Meckelin (Transmembrane protein 67) TFIIA PF03153.13 EKX39266.1 - 0.086 12.8 18.1 0.11 12.5 18.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Gly_radical PF01228.21 EKX39266.1 - 0.19 12.3 0.8 3.7 8.1 0.0 2.7 2 1 1 3 3 3 0 Glycine radical Tsg PF04668.12 EKX39266.1 - 9.8 6.9 9.9 3.7 8.2 2.3 2.3 2 1 0 2 2 2 0 Twisted gastrulation (Tsg) protein conserved region DIOX_N PF14226.6 EKX39267.1 - 2.4e-33 115.4 0.0 3.6e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EKX39267.1 - 8.4e-07 29.4 0.0 1.6e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Chorein_N PF12624.7 EKX39268.1 - 3.5e-16 59.4 4.7 2e-15 56.9 0.0 3.5 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 EKX39268.1 - 0.00014 21.3 0.0 0.00042 19.8 0.0 1.9 1 1 0 1 1 1 1 SHR-binding domain of vacuolar-sorting associated protein 13 Sugar_tr PF00083.24 EKX39270.1 - 1.1e-58 199.2 27.4 6.6e-58 196.7 27.4 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EKX39270.1 - 8.2e-18 64.4 21.8 8.2e-18 64.4 21.8 2.2 1 1 0 2 2 2 1 Major Facilitator Superfamily zf-RING_2 PF13639.6 EKX39271.1 - 1.9e-08 34.5 15.2 1.9e-08 34.5 15.2 2.2 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX39271.1 - 9.5e-07 28.6 14.4 2.6e-06 27.2 14.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EKX39271.1 - 4.7e-06 26.2 5.1 4.7e-06 26.2 5.1 2.1 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EKX39271.1 - 6.6e-05 22.7 18.9 0.00022 21.1 18.9 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX39271.1 - 7.6e-05 22.9 15.7 7.6e-05 22.9 15.7 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EKX39271.1 - 0.00033 20.6 8.4 0.0013 18.7 8.4 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EKX39271.1 - 0.0069 16.3 17.4 0.026 14.5 17.4 2.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 EKX39271.1 - 0.039 13.8 13.3 0.14 12.0 13.3 2.0 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.6 EKX39271.1 - 0.56 10.1 24.5 0.061 13.2 19.6 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ADH_N PF08240.12 EKX39271.1 - 1.7 8.6 8.2 4.9 7.1 8.2 1.8 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain zf-ANAPC11 PF12861.7 EKX39271.1 - 2.7 8.1 16.3 9.5 6.4 14.1 2.7 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger Spt20 PF12090.8 EKX39273.1 - 0.078 12.6 0.4 0.088 12.4 0.4 1.1 1 0 0 1 1 1 0 Spt20 family Pns11_12 PF17464.2 EKX39273.1 - 0.099 12.3 3.9 0.1 12.3 3.9 1.1 1 0 0 1 1 1 0 Non-structural protein 11 and 12 DUF4337 PF14235.6 EKX39273.1 - 0.77 9.9 3.5 0.92 9.6 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Ank_2 PF12796.7 EKX39274.1 - 2.2e-21 76.2 5.0 2.8e-11 43.8 0.6 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX39274.1 - 5.4e-18 65.1 0.7 2.9e-08 34.1 0.1 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX39274.1 - 1.9e-13 49.3 1.4 0.021 15.3 0.0 5.6 4 1 1 5 5 5 3 Ankyrin repeat Ank PF00023.30 EKX39274.1 - 2.7e-11 43.4 4.2 0.00081 19.7 0.1 5.2 4 1 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EKX39274.1 - 1e-09 38.4 1.5 0.0012 19.1 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) CCDC53 PF10152.9 EKX39274.1 - 0.026 14.9 0.1 0.044 14.2 0.1 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF2520 PF10728.9 EKX39274.1 - 0.027 14.3 0.8 0.19 11.5 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2520) AlaDh_PNT_N PF05222.15 EKX39274.1 - 0.082 13.2 0.1 1 9.7 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, N-terminal domain Folate_carrier PF01770.18 EKX39274.1 - 0.27 9.9 2.5 1.8 7.2 0.2 2.1 2 0 0 2 2 2 0 Reduced folate carrier MORN PF02493.20 EKX39275.1 - 5e-22 76.4 17.3 7.4e-05 22.4 0.0 5.7 5 1 0 5 5 5 5 MORN repeat SPRY PF00622.28 EKX39277.1 - 3.5e-07 30.3 0.0 6.2e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Ank_4 PF13637.6 EKX39278.1 - 3.8e-11 43.3 0.4 2.4e-05 24.8 0.0 3.2 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX39278.1 - 5.9e-10 39.6 1.8 4.7e-05 23.9 0.4 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX39278.1 - 3.7e-06 26.9 1.2 3.1 8.7 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EKX39278.1 - 0.00012 22.3 1.3 0.39 11.2 0.1 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EKX39278.1 - 0.0021 18.3 0.8 2.7 8.4 0.0 3.8 2 1 2 4 4 4 1 Ankyrin repeats (many copies) RF-1 PF00472.20 EKX39279.1 - 7.3e-17 61.4 1.7 1.2e-16 60.7 1.7 1.2 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.9 EKX39279.1 - 0.0072 16.7 4.0 0.02 15.3 4.0 1.7 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit protein XLF PF09302.11 EKX39279.1 - 0.011 16.0 0.5 0.014 15.6 0.5 1.2 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Fungal_lectin_2 PF18647.1 EKX39279.1 - 0.031 14.7 0.2 0.047 14.1 0.2 1.4 1 0 0 1 1 1 0 Alpha-galactosyl-binding fungal lectin Sua5_yciO_yrdC PF01300.18 EKX39282.1 - 4.8e-52 176.1 0.0 2.1e-51 173.9 0.0 1.8 2 0 0 2 2 2 1 Telomere recombination SUA5 PF03481.13 EKX39282.1 - 1.5e-25 90.3 0.1 2.3e-25 89.7 0.1 1.2 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding ACP_syn_III_C PF08541.10 EKX39283.1 - 0.0022 18.1 2.6 15 5.8 0.1 3.3 3 0 0 3 3 3 3 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Phage_gp49_66 PF13876.6 EKX39283.1 - 0.007 16.6 5.1 24 5.3 0.0 4.5 5 0 0 5 5 5 2 Phage protein (N4 Gp49/phage Sf6 gene 66) family DUF2563 PF10817.8 EKX39283.1 - 0.038 14.6 4.0 12 6.5 0.2 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2563) DUF1623 PF07785.11 EKX39283.1 - 0.088 13.0 0.8 83 3.5 0.0 3.5 2 1 0 3 3 3 0 Protein of unknown function (DUF1623) Alpha_E2_glycop PF00943.19 EKX39283.1 - 1.1 7.9 14.6 2.4 6.8 1.1 3.0 1 1 2 3 3 3 0 Alphavirus E2 glycoprotein TTL PF03133.15 EKX39284.1 - 1.1e-54 185.6 0.0 1.3e-54 185.3 0.0 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EKX39284.1 - 1.7e-08 34.0 0.0 8.3e-07 28.5 0.0 2.3 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EKX39284.1 - 0.13 11.5 0.2 0.61 9.3 0.0 2.0 2 1 1 3 3 3 0 Sugar-transfer associated ATP-grasp Patatin PF01734.22 EKX39285.1 - 7.9e-11 42.5 2.3 0.00012 22.3 1.2 2.2 1 1 1 2 2 2 2 Patatin-like phospholipase DnaJ PF00226.31 EKX39287.1 - 5.4e-24 84.1 1.8 5.4e-24 84.1 1.8 2.4 2 1 0 2 2 2 1 DnaJ domain Pex14_N PF04695.13 EKX39287.1 - 0.093 13.4 3.1 0.18 12.4 3.1 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MORN PF02493.20 EKX39288.1 - 9.8e-21 72.4 18.3 4.1e-06 26.4 1.0 6.1 6 0 0 6 6 6 5 MORN repeat Tudor_2 PF18104.1 EKX39288.1 - 0.0019 17.9 1.0 0.38 10.5 0.6 3.4 4 0 0 4 4 4 1 Jumonji domain-containing protein 2A Tudor domain Glyco_transf_90 PF05686.12 EKX39289.1 - 4.8e-13 48.8 0.6 6.2e-13 48.4 0.6 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 90 GLF PF03275.13 EKX39290.1 - 9e-64 215.0 0.5 1.6e-63 214.1 0.5 1.4 1 1 0 1 1 1 1 UDP-galactopyranose mutase NAD_binding_8 PF13450.6 EKX39290.1 - 1.6e-17 63.5 0.4 1.5e-16 60.4 0.1 2.5 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EKX39290.1 - 2.7e-05 23.7 0.0 6.7e-05 22.4 0.0 1.6 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 EKX39290.1 - 0.00082 19.4 0.0 0.0023 18.0 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EKX39290.1 - 0.12 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sybindin PF04099.12 EKX39292.1 - 3.8e-22 78.8 0.0 4.5e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EKX39292.1 - 0.031 14.4 0.0 0.04 14.0 0.0 1.1 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region Ribosomal_L29 PF00831.23 EKX39293.1 - 5.5e-17 61.5 0.6 5.5e-17 61.5 0.6 2.3 2 0 0 2 2 2 1 Ribosomal L29 protein MTBP_C PF14920.6 EKX39293.1 - 0.014 15.1 0.9 0.027 14.2 0.9 1.3 1 0 0 1 1 1 0 MDM2-binding TP6A_N PF04406.14 EKX39294.1 - 5e-19 68.0 0.3 9.5e-19 67.1 0.3 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase TP6A_N PF04406.14 EKX39295.1 - 5e-19 68.0 0.3 1.1e-18 66.9 0.3 1.7 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Radical_SAM PF04055.21 EKX39298.1 - 5.4e-32 111.5 0.0 1.4e-31 110.1 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.20 EKX39298.1 - 1.3e-23 82.9 0.0 3.1e-23 81.6 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 EKX39298.1 - 0.00015 21.6 0.0 0.00031 20.7 0.0 1.5 1 0 0 1 1 1 1 TRAM domain Fer4_12 PF13353.6 EKX39298.1 - 0.059 13.6 0.3 1.4 9.2 0.0 2.9 4 0 0 4 4 4 0 4Fe-4S single cluster domain DUF2607 PF10795.9 EKX39299.1 - 0.0029 17.7 0.0 0.0051 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2607) Syja_N PF02383.18 EKX39300.1 - 5.6e-64 216.5 0.0 7.7e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Cytochrome_C7 PF14522.6 EKX39300.1 - 0.06 13.4 0.3 0.13 12.2 0.3 1.6 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c DUF2525 PF10733.9 EKX39300.1 - 0.096 13.0 0.1 4.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2525) Methyltransf_16 PF10294.9 EKX39302.1 - 2.7e-14 53.3 0.0 3.6e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Arf PF00025.21 EKX39303.1 - 1.2e-76 256.1 0.0 1.4e-76 255.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EKX39303.1 - 1.3e-14 54.5 0.0 1.7e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EKX39303.1 - 5.9e-14 52.0 0.0 6.9e-14 51.8 0.0 1.0 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EKX39303.1 - 8.5e-12 44.9 0.0 1.1e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EKX39303.1 - 7.3e-11 41.8 0.3 5.9e-07 29.0 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EKX39303.1 - 2.1e-08 33.8 0.0 2.6e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EKX39303.1 - 2e-06 27.8 0.0 4.3e-06 26.8 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EKX39303.1 - 0.0061 16.1 0.8 0.057 13.0 0.8 2.5 1 1 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 EKX39303.1 - 0.012 14.7 0.2 0.15 11.0 0.0 2.3 2 1 1 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 EKX39303.1 - 0.028 14.2 0.1 5.9 6.6 0.0 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 EKX39303.1 - 0.073 13.6 0.0 0.096 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Ank_3 PF13606.6 EKX39304.1 - 1e-12 47.0 6.1 0.0034 17.7 0.1 5.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 EKX39304.1 - 3.6e-12 46.5 1.9 5e-06 27.0 0.2 4.7 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX39304.1 - 1.8e-11 44.5 0.1 0.00015 22.3 0.1 3.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX39304.1 - 8e-09 35.6 0.6 0.0014 18.9 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX39304.1 - 9e-08 32.2 1.6 0.16 12.5 0.4 4.8 4 0 0 4 4 4 2 Ankyrin repeat DuoxA PF10204.9 EKX39304.1 - 0.7 8.8 4.4 1.3 7.9 4.4 1.4 1 0 0 1 1 1 0 Dual oxidase maturation factor DUF2207 PF09972.9 EKX39305.1 - 0.38 9.4 0.6 9 4.9 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) ADK PF00406.22 EKX39306.1 - 1.6e-43 148.4 0.0 2.1e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EKX39306.1 - 1.2e-26 93.8 0.0 1.6e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EKX39306.1 - 1.9e-07 31.7 0.0 7.8e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 EKX39306.1 - 0.0014 19.0 0.7 0.87 9.8 0.0 2.2 1 1 1 2 2 2 2 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 EKX39306.1 - 0.024 14.8 0.0 0.081 13.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain ADK_lid PF05191.14 EKX39306.1 - 0.029 14.4 0.1 0.057 13.4 0.1 1.5 1 0 0 1 1 1 0 Adenylate kinase, active site lid Thymidylate_kin PF02223.17 EKX39306.1 - 0.031 13.9 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase SPRY PF00622.28 EKX39307.1 - 9.1e-05 22.6 0.0 0.00011 22.3 0.0 1.1 1 0 0 1 1 1 1 SPRY domain CART PF06373.11 EKX39307.1 - 0.036 14.2 0.0 0.072 13.3 0.0 1.5 1 0 0 1 1 1 0 Cocaine and amphetamine regulated transcript protein (CART) NMT_C PF02799.15 EKX39308.1 - 4.9e-73 245.1 0.0 6.2e-73 244.8 0.0 1.1 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 EKX39308.1 - 1.2e-71 239.8 0.0 2.5e-71 238.7 0.0 1.5 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.25 EKX39308.1 - 0.00016 21.9 0.0 0.00039 20.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EKX39308.1 - 0.041 14.0 0.0 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EKX39308.1 - 0.05 13.5 0.0 0.099 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EKX39308.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_7 PF13508.7 EKX39308.1 - 0.17 12.3 0.0 0.51 10.8 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Helicase_C PF00271.31 EKX39309.1 - 5.2e-16 59.0 0.0 3.6e-14 53.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EKX39309.1 - 2.2e-15 56.9 0.0 3.9e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EKX39309.1 - 3.3e-05 23.9 0.0 0.00016 21.7 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit LysM PF01476.20 EKX39310.1 - 3.2e-07 30.3 0.0 4.5e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 LysM domain HrpB2 PF09487.10 EKX39311.1 - 0.011 16.2 0.1 4.2 7.8 0.1 2.4 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) RNase_HII PF01351.18 EKX39312.1 - 2.6e-27 96.0 0.0 4e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease HII zinc_ribbon_12 PF11331.8 EKX39313.1 - 0.078 12.8 0.1 0.2 11.5 0.1 1.7 1 0 0 1 1 1 0 Probable zinc-ribbon domain RRS1 PF04939.12 EKX39315.1 - 1.5e-11 44.4 12.3 1.5e-11 44.4 12.3 2.3 2 1 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) Glyco_hydro_2_C PF02836.17 EKX39316.1 - 5.5e-78 262.1 0.3 1.5e-77 260.7 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 EKX39316.1 - 7.5e-32 110.6 0.0 1.8e-31 109.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 EKX39316.1 - 3.3e-11 43.8 0.0 7.5e-11 42.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 bZIP_1 PF00170.21 EKX39319.1 - 4.4e-14 52.3 12.7 1.3e-13 50.8 12.7 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EKX39319.1 - 3.8e-09 36.5 11.0 3.8e-09 36.5 11.0 2.7 2 1 1 3 3 2 2 Basic region leucine zipper bZIP_Maf PF03131.17 EKX39319.1 - 3.3e-06 27.5 9.0 3.3e-06 27.5 9.0 2.3 1 1 1 2 2 2 1 bZIP Maf transcription factor HAUS-augmin3 PF14932.6 EKX39319.1 - 0.00052 19.7 9.5 0.0011 18.7 9.5 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 HALZ PF02183.18 EKX39319.1 - 0.00076 19.7 4.1 0.059 13.6 2.6 2.6 1 1 1 2 2 2 2 Homeobox associated leucine zipper JIP_LZII PF16471.5 EKX39319.1 - 0.075 13.2 3.3 0.072 13.3 1.3 2.0 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II FAD-SLDH PF12318.8 EKX39319.1 - 0.27 11.3 1.2 0.47 10.5 1.2 1.4 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase APG6_N PF17675.1 EKX39319.1 - 0.32 11.5 15.1 0.8 10.2 15.1 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region Seryl_tRNA_N PF02403.22 EKX39319.1 - 0.64 10.3 13.7 1.8 8.9 13.7 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Jnk-SapK_ap_N PF09744.9 EKX39319.1 - 1.9 8.7 13.7 3.5 7.8 13.7 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 TMF_TATA_bd PF12325.8 EKX39319.1 - 2 8.7 13.5 0.4 10.9 9.8 1.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding TMA7 PF09072.10 EKX39319.1 - 2.9 8.8 10.2 0.56 11.1 2.6 2.6 2 0 0 2 2 2 0 Translation machinery associated TMA7 LCD1 PF09798.9 EKX39319.1 - 3 6.2 11.0 4.5 5.7 11.0 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein Frag1 PF10277.9 EKX39320.1 - 3.6e-06 26.7 10.2 5.9e-06 26.0 10.2 1.3 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Ferric_reduct PF01794.19 EKX39320.1 - 0.017 15.2 2.0 0.017 15.2 2.0 2.0 1 1 1 2 2 2 0 Ferric reductase like transmembrane component DUF3341 PF11821.8 EKX39320.1 - 3.7 7.2 6.1 0.75 9.4 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3341) Redoxin PF08534.10 EKX39321.1 - 6.2e-27 94.1 0.0 7.7e-27 93.8 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EKX39321.1 - 6.5e-14 51.9 0.0 7.8e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF2704 PF10866.8 EKX39323.1 - 0.019 14.9 2.0 0.034 14.0 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2704) DUF416 PF04222.12 EKX39323.1 - 0.033 13.6 2.2 0.077 12.4 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF416) Stork_head PF10264.9 EKX39323.1 - 0.11 12.7 0.1 19 5.5 0.0 2.7 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain DUF4226 PF10774.9 EKX39323.1 - 0.16 12.3 3.5 0.26 11.6 1.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4226) MMR_HSR1 PF01926.23 EKX39324.1 - 8.9e-10 38.7 0.0 6.3e-05 23.0 0.0 2.7 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EKX39324.1 - 0.00023 21.6 0.1 0.00048 20.6 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EKX39324.1 - 0.00048 20.1 1.1 0.0021 18.0 0.0 2.4 2 1 1 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 EKX39324.1 - 0.0015 18.7 0.5 0.013 15.5 0.5 2.2 1 1 0 1 1 1 1 Dynamin family Roc PF08477.13 EKX39324.1 - 0.0038 17.4 0.0 0.012 15.9 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 EKX39324.1 - 0.0044 16.4 0.0 0.0083 15.6 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein FeoB_N PF02421.18 EKX39324.1 - 0.0063 16.1 0.1 0.1 12.1 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EKX39324.1 - 0.024 14.2 0.0 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Ras PF00071.22 EKX39324.1 - 0.071 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Ras family AAA_28 PF13521.6 EKX39324.1 - 0.075 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EKX39324.1 - 0.14 12.5 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain TPT PF03151.16 EKX39325.1 - 0.0031 16.9 9.4 0.0031 16.9 9.4 2.0 1 1 0 2 2 2 1 Triose-phosphate Transporter family Fibroin_P25 PF07294.11 EKX39325.1 - 0.012 15.6 0.4 0.17 11.9 0.1 2.1 2 0 0 2 2 2 0 Fibroin P25 EamA PF00892.20 EKX39325.1 - 0.071 13.3 15.9 1.4 9.1 0.2 2.6 1 1 0 2 2 2 0 EamA-like transporter family Beta_helix PF13229.6 EKX39326.1 - 4.3e-19 68.9 4.2 2.9e-14 53.2 0.1 2.3 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 EKX39326.1 - 1.5e-12 47.4 2.2 4.4e-11 42.5 0.2 2.2 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.11 EKX39326.1 - 1.1e-05 24.9 1.8 0.0002 20.8 1.9 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1565) EFG_II PF14492.6 EKX39326.1 - 0.07 13.2 0.4 5.8 7.1 0.0 2.4 2 0 0 2 2 2 0 Elongation Factor G, domain II MFS_5 PF05631.14 EKX39327.1 - 1.1e-50 172.6 8.3 2.1e-26 92.7 0.6 3.0 1 1 2 3 3 3 3 Sugar-tranasporters, 12 TM COX8 PF02285.15 EKX39327.1 - 0.025 14.4 0.4 0.025 14.4 0.4 2.2 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII GPAT_N PF14829.6 EKX39329.1 - 0.041 13.9 1.9 4.2 7.4 0.0 2.8 3 0 0 3 3 3 0 Glycerol-3-phosphate acyltransferase N-terminal DUF2681 PF10883.8 EKX39330.1 - 0.048 14.1 0.1 0.077 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) CLN3 PF02487.17 EKX39330.1 - 0.12 11.4 0.1 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 CLN3 protein EphA2_TM PF14575.6 EKX39330.1 - 0.14 13.1 0.1 0.17 12.7 0.1 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Conotoxin PF02950.17 EKX39330.1 - 0.25 12.4 0.1 0.59 11.2 0.1 1.6 1 0 0 1 1 1 0 Conotoxin Frizzled PF01534.17 EKX39331.1 - 0.037 13.1 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region DUF2070 PF09843.9 EKX39331.1 - 0.36 9.1 4.5 0.44 8.8 4.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF4149 PF13664.6 EKX39331.1 - 3.6 8.0 8.5 2 8.8 1.8 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4149) AMP-binding PF00501.28 EKX39332.1 - 1.2e-11 43.9 0.0 1.4e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme V_ATPase_I_N PF18670.1 EKX39332.1 - 0.015 15.7 0.0 0.029 14.8 0.0 1.5 1 0 0 1 1 1 0 V-type ATPase subunit I, N-terminal domain PH PF00169.29 EKX39333.1 - 1.1e-10 41.9 0.1 1.6e-10 41.4 0.1 1.4 1 1 0 1 1 1 1 PH domain WD-3 PF09765.9 EKX39334.1 - 2.8e-63 213.9 0.5 3.2e-63 213.7 0.5 1.0 1 0 0 1 1 1 1 WD-repeat region FANCL_C PF11793.8 EKX39334.1 - 1.5e-23 82.7 4.0 2.7e-23 81.9 4.0 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 EKX39334.1 - 0.044 14.1 2.5 0.096 13.0 2.5 1.6 1 0 0 1 1 1 0 Ring finger domain RINGv PF12906.7 EKX39334.1 - 0.22 11.7 1.1 0.47 10.6 1.1 1.6 1 0 0 1 1 1 0 RING-variant domain RCC1 PF00415.18 EKX39335.1 - 4.6e-35 120.0 17.5 3.7e-12 46.7 0.1 8.0 7 2 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX39335.1 - 3.1e-28 97.0 19.3 3.7e-09 36.2 0.1 6.9 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Pkinase PF00069.25 EKX39335.1 - 2.2e-26 92.8 0.0 3.4e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX39335.1 - 1.1e-15 57.6 0.0 1.8e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Hira PF07569.11 EKX39335.1 - 0.00059 19.6 0.0 10 5.8 0.1 4.1 3 1 1 4 4 4 1 TUP1-like enhancer of split Phage_Gp17 PF17549.2 EKX39336.1 - 0.2 11.7 0.8 0.42 10.6 0.8 1.4 1 0 0 1 1 1 0 Gene Product 17 Thioredoxin PF00085.20 EKX39337.1 - 1.3e-14 54.0 0.0 1.9e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 EKX39337.1 - 0.0028 17.4 0.0 0.0074 16.1 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin OST3_OST6 PF04756.13 EKX39337.1 - 0.035 13.5 0.0 0.048 13.0 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family OB_RNB PF08206.11 EKX39337.1 - 0.065 12.9 0.3 10 5.9 0.1 2.3 2 0 0 2 2 2 0 Ribonuclease B OB domain Thioredoxin_3 PF13192.6 EKX39337.1 - 0.08 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_2 PF13098.6 EKX39337.1 - 0.14 12.6 0.0 0.42 11.1 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain Myc_N PF01056.18 EKX39338.1 - 0.071 13.0 1.5 0.089 12.7 1.5 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF3682 PF12446.8 EKX39338.1 - 2.3 8.7 10.6 4.8 7.7 10.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Collagen PF01391.18 EKX39339.1 - 4.4e-24 84.0 72.3 5.9e-09 35.6 26.6 3.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) WD40 PF00400.32 EKX39340.1 - 9.4e-39 130.7 10.7 9.1e-14 51.7 0.1 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX39340.1 - 4.1e-14 52.7 0.0 5.9e-05 23.3 0.0 3.4 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EKX39340.1 - 4.4e-07 30.0 0.0 0.047 13.6 0.0 2.7 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EKX39340.1 - 0.0005 19.5 0.0 0.042 13.2 0.0 2.0 2 0 0 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 EKX39340.1 - 0.0043 16.1 0.0 0.29 10.1 0.0 2.3 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 EKX39340.1 - 0.012 13.9 0.0 0.17 10.1 0.0 2.0 1 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 EKX39340.1 - 0.026 13.3 0.0 2.4 6.8 0.0 2.6 2 1 0 2 2 2 0 Nup133 N terminal like Nup160 PF11715.8 EKX39340.1 - 0.028 13.1 0.1 13 4.3 0.0 2.9 1 1 1 3 3 3 0 Nucleoporin Nup120/160 PD40 PF07676.12 EKX39340.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat RAB3GAP2_N PF14655.6 EKX39340.1 - 0.11 11.8 0.0 0.98 8.6 0.0 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Amastin PF07344.11 EKX39342.1 - 0.0047 16.8 3.3 0.0047 16.8 3.3 1.6 1 1 1 2 2 2 1 Amastin surface glycoprotein Acetyltransf_1 PF00583.25 EKX39343.1 - 0.00035 20.8 0.0 0.052 13.8 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EKX39343.1 - 0.026 14.5 0.1 0.083 12.9 0.0 1.7 1 1 1 2 2 2 0 FR47-like protein Ank_2 PF12796.7 EKX39344.1 - 0.011 16.3 0.0 0.029 15.0 0.0 1.7 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.30 EKX39344.1 - 0.063 13.7 0.0 0.56 10.7 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat DUF2089 PF09862.9 EKX39344.1 - 0.087 12.9 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) BLOC1_2 PF10046.9 EKX39345.1 - 0.0026 18.0 2.0 0.0026 18.0 2.0 2.2 2 1 1 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_10 PF13374.6 EKX39345.1 - 0.063 13.2 1.8 0.3 11.0 0.3 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Fructosamin_kin PF03881.14 EKX39345.1 - 0.1 11.8 0.5 0.27 10.4 0.5 1.6 1 1 0 1 1 1 0 Fructosamine kinase DUF3209 PF11483.8 EKX39345.1 - 0.13 12.7 4.2 5.9 7.4 1.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3209) TerB PF05099.13 EKX39345.1 - 0.14 12.1 7.1 0.16 11.9 5.1 2.1 2 1 0 2 2 2 0 Tellurite resistance protein TerB FERM_M PF00373.18 EKX39345.1 - 1 9.7 4.3 0.61 10.5 1.4 2.1 1 1 1 2 2 2 0 FERM central domain CLZ PF16526.5 EKX39345.1 - 1.2 9.5 8.5 0.52 10.7 4.2 2.6 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ADIP PF11559.8 EKX39345.1 - 3.7 7.6 15.4 0.042 13.9 4.3 2.7 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 EKX39345.1 - 7 6.8 19.9 0.39 10.9 12.5 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) MRP-L46 PF11788.8 EKX39346.1 - 1.8e-05 25.4 0.8 0.00011 23.0 0.2 2.4 1 1 1 2 2 2 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 EKX39346.1 - 0.012 15.7 0.3 0.032 14.3 0.0 1.9 2 1 0 2 2 2 0 NUDIX domain Heme_oxygenase PF01126.20 EKX39348.1 - 0.0001 22.2 0.2 0.00013 21.8 0.2 1.2 1 0 0 1 1 1 1 Heme oxygenase Pox_D5 PF03288.16 EKX39348.1 - 0.01 16.3 0.1 0.027 15.0 0.1 1.7 1 0 0 1 1 1 0 Poxvirus D5 protein-like PRIMA1 PF16101.5 EKX39348.1 - 0.89 9.6 12.0 0.59 10.2 10.0 1.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 UQ_con PF00179.26 EKX39349.1 - 5.2e-10 39.1 0.0 5.2e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme NAD_Gly3P_dh_C PF07479.14 EKX39350.1 - 1.3e-45 155.2 0.2 6e-45 153.0 0.0 2.1 3 0 0 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 EKX39350.1 - 9.8e-41 139.3 0.1 1.3e-38 132.5 0.1 2.2 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 EKX39350.1 - 0.022 15.3 0.1 0.68 10.6 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pkinase_Tyr PF07714.17 EKX39351.1 - 3.6e-46 157.5 0.0 4.4e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX39351.1 - 7e-36 123.9 0.0 8.3e-36 123.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EKX39351.1 - 0.0027 17.7 0.3 0.014 15.3 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX39351.1 - 0.0085 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EKX39351.1 - 0.16 11.6 0.1 0.3 10.7 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Guanylate_cyc PF00211.20 EKX39352.1 - 1e-46 158.9 0.0 1.1e-46 158.7 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HU-HIG PF18291.1 EKX39352.1 - 0.055 13.6 0.0 0.1 12.7 0.0 1.5 1 1 0 1 1 1 0 HU domain fused to wHTH, Ig, or Glycine-rich motif PHD PF00628.29 EKX39353.1 - 8.9e-12 44.7 9.0 9.8e-12 44.6 9.0 1.0 1 0 0 1 1 1 1 PHD-finger C1_2 PF03107.16 EKX39353.1 - 0.004 17.4 5.8 0.004 17.4 5.8 1.5 2 0 0 2 2 2 1 C1 domain Prok-RING_1 PF14446.6 EKX39353.1 - 0.0064 16.4 5.1 0.01 15.8 5.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PHD_2 PF13831.6 EKX39353.1 - 0.021 14.4 3.8 0.021 14.4 3.8 2.0 2 0 0 2 2 2 0 PHD-finger zf-PHD-like PF15446.6 EKX39353.1 - 0.021 14.4 1.8 0.026 14.1 1.8 1.1 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain FANCL_C PF11793.8 EKX39353.1 - 0.04 14.1 3.9 0.046 13.9 3.9 1.1 1 0 0 1 1 1 0 FANCL C-terminal domain Zf_RING PF16744.5 EKX39353.1 - 3.1 8.0 10.7 0.068 13.3 4.9 1.4 1 1 1 2 2 2 0 KIAA1045 RING finger LMBR1 PF04791.16 EKX39354.1 - 0.037 13.0 7.6 0.064 12.2 0.2 2.1 1 1 1 2 2 2 0 LMBR1-like membrane protein CHGN PF05679.16 EKX39355.1 - 0.18 10.6 4.9 0.28 10.0 4.9 1.3 1 0 0 1 1 1 0 Chondroitin N-acetylgalactosaminyltransferase AAA_23 PF13476.6 EKX39355.1 - 0.32 11.4 12.7 0.095 13.2 9.6 1.7 2 0 0 2 2 2 0 AAA domain SKA1 PF07160.12 EKX39355.1 - 2.1 8.1 15.6 2.5 7.9 14.6 1.7 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 SPX PF03105.19 EKX39355.1 - 2.5 7.9 22.4 0.15 11.9 17.3 1.5 2 0 0 2 2 2 0 SPX domain JmjC PF02373.22 EKX39356.1 - 5.9e-11 42.8 3.4 8.7e-11 42.3 0.1 2.6 3 0 0 3 3 3 1 JmjC domain, hydroxylase JmjN PF02375.17 EKX39356.1 - 0.0003 20.7 0.0 0.00064 19.6 0.0 1.6 1 0 0 1 1 1 1 jmjN domain UVR PF02151.19 EKX39358.1 - 3.5e-07 29.7 9.7 0.00016 21.3 3.0 2.6 2 0 0 2 2 2 2 UvrB/uvrC motif RE_HindIII PF09518.10 EKX39358.1 - 0.34 10.1 4.1 0.57 9.3 4.1 1.3 1 1 0 1 1 1 0 HindIII restriction endonuclease AAA_lid_9 PF17871.1 EKX39358.1 - 1.1 9.2 8.0 0.65 9.9 1.5 2.2 1 1 1 2 2 2 0 AAA lid domain UAA PF08449.11 EKX39359.1 - 2.4e-46 158.4 6.5 2.8e-46 158.1 6.5 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EKX39359.1 - 2.1e-05 24.7 13.9 0.00015 21.9 0.5 2.6 2 1 0 2 2 2 2 EamA-like transporter family Helicase_C_2 PF13307.6 EKX39359.1 - 0.078 13.1 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain TMEM234 PF10639.9 EKX39359.1 - 0.14 12.2 1.5 9.8 6.2 0.1 2.7 2 0 0 2 2 2 0 Putative transmembrane family 234 IFT46_B_C PF12317.8 EKX39360.1 - 2.8e-91 305.0 0.2 3.3e-91 304.8 0.2 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal LysM PF01476.20 EKX39362.1 - 2.8e-05 24.1 0.0 0.23 11.6 0.0 2.3 2 0 0 2 2 2 2 LysM domain FemAB_like PF04339.12 EKX39363.1 - 3.8e-146 487.0 1.9 4.3e-146 486.8 1.9 1.0 1 0 0 1 1 1 1 Peptidogalycan biosysnthesis/recognition Acetyltransf_6 PF13480.7 EKX39363.1 - 1.4e-12 47.9 0.5 1.4e-12 47.9 0.5 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Relaxase PF03432.14 EKX39363.1 - 0.0062 16.2 0.2 0.0095 15.6 0.2 1.2 1 0 0 1 1 1 1 Relaxase/Mobilisation nuclease domain FemAB PF02388.16 EKX39363.1 - 0.013 14.4 0.5 0.021 13.7 0.5 1.2 1 0 0 1 1 1 0 FemAB family Guanylate_cyc PF00211.20 EKX39364.1 - 2.3e-53 180.5 0.0 2.6e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Isochorismatase PF00857.20 EKX39365.1 - 3.9e-31 108.6 0.0 4.5e-31 108.4 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family HMG_box PF00505.19 EKX39367.1 - 4e-19 68.8 0.6 5.7e-19 68.3 0.6 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EKX39367.1 - 9.9e-09 35.7 0.1 1.4e-08 35.2 0.1 1.2 1 0 0 1 1 1 1 HMG-box domain CNDH2_C PF16858.5 EKX39367.1 - 0.022 14.7 0.0 0.025 14.5 0.0 1.0 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term HMG_box PF00505.19 EKX39368.1 - 1.5e-19 70.1 0.6 2e-19 69.8 0.6 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EKX39368.1 - 3.9e-09 37.0 0.3 4.8e-09 36.7 0.3 1.1 1 0 0 1 1 1 1 HMG-box domain ABC1 PF03109.16 EKX39370.1 - 3.5e-18 65.9 0.0 6.3e-17 61.9 0.0 2.4 1 1 0 1 1 1 1 ABC1 family APH PF01636.23 EKX39370.1 - 0.0016 18.4 0.1 0.033 14.1 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EKX39370.1 - 0.0064 15.8 0.1 0.25 10.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DUF4446 PF14584.6 EKX39371.1 - 0.037 14.0 0.5 0.073 13.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) GrpE PF01025.19 EKX39371.1 - 0.28 10.9 4.5 0.47 10.1 4.5 1.3 1 0 0 1 1 1 0 GrpE Sulfotransfer_2 PF03567.14 EKX39372.1 - 1e-12 48.6 14.2 4.5e-11 43.1 5.2 3.4 2 1 0 2 2 2 2 Sulfotransferase family ANAPC4_WD40 PF12894.7 EKX39374.1 - 2.6e-05 24.4 0.1 0.0023 18.2 0.0 3.3 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EKX39374.1 - 4.6e-05 24.1 1.8 0.0044 17.8 0.0 3.9 4 1 0 4 4 4 1 WD domain, G-beta repeat RAB3GAP2_N PF14655.6 EKX39374.1 - 0.042 13.1 2.7 1.7 7.8 0.0 2.9 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Rav1p_C PF12234.8 EKX39374.1 - 0.046 12.1 0.1 0.046 12.1 0.1 1.9 2 0 0 2 2 2 0 RAVE protein 1 C terminal Nbas_N PF15492.6 EKX39374.1 - 0.073 12.4 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 EKX39374.1 - 0.085 12.2 0.1 0.32 10.3 0.1 1.8 1 1 0 1 1 1 0 WD40-like domain Topoisom_I_N PF02919.15 EKX39375.1 - 7.6e-84 280.5 1.8 7.6e-84 280.5 1.8 3.6 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 EKX39375.1 - 9.8e-80 267.1 6.8 9.8e-80 267.1 6.8 2.6 1 1 1 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 EKX39375.1 - 2.4e-26 91.5 1.0 1.2e-25 89.2 1.0 2.3 1 0 0 1 1 1 1 C-terminal topoisomerase domain DSBA PF01323.20 EKX39375.1 - 0.05 13.4 0.5 0.13 12.1 0.2 1.8 2 0 0 2 2 2 0 DSBA-like thioredoxin domain DUF3246 PF11596.8 EKX39375.1 - 0.2 11.1 6.0 0.33 10.3 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) XhlA PF10779.9 EKX39375.1 - 1.4 9.2 8.9 4.1 7.7 0.8 3.2 1 1 1 2 2 2 0 Haemolysin XhlA PSI_PsaF PF02507.15 EKX39375.1 - 2.4 8.0 4.0 6.5 6.6 1.2 2.6 1 1 1 2 2 2 0 Photosystem I reaction centre subunit III ING PF12998.7 EKX39377.1 - 2.8 8.6 7.1 1.3 9.7 3.0 2.2 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding WW PF00397.26 EKX39378.1 - 2.2e-11 43.6 2.7 3.3e-11 43.1 2.7 1.3 1 0 0 1 1 1 1 WW domain LRR_4 PF12799.7 EKX39379.1 - 3.7e-07 30.3 1.3 6.7e-05 23.2 0.1 2.8 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) p25-alpha PF05517.12 EKX39379.1 - 9.7e-07 29.1 13.1 1.5e-06 28.4 0.0 4.5 5 1 0 5 5 5 2 p25-alpha LRR_8 PF13855.6 EKX39379.1 - 0.0078 16.0 2.3 0.061 13.1 2.3 2.3 1 1 0 1 1 1 1 Leucine rich repeat FlaC_arch PF05377.11 EKX39379.1 - 0.0079 16.6 2.9 0.033 14.6 2.6 2.3 1 1 0 1 1 1 1 Flagella accessory protein C (FlaC) bZIP_1 PF00170.21 EKX39379.1 - 0.016 15.3 4.4 0.042 13.9 3.2 2.4 1 1 0 1 1 1 0 bZIP transcription factor Baculo_PEP_C PF04513.12 EKX39379.1 - 0.044 13.8 2.7 0.088 12.8 2.7 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Plectin PF00681.20 EKX39379.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Plectin repeat DUF948 PF06103.11 EKX39379.1 - 0.57 10.5 2.3 1.3 9.3 2.3 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) SRP54 PF00448.22 EKX39380.1 - 6.9e-49 166.1 0.8 6.4e-48 163.0 0.8 2.0 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain MeaB PF03308.16 EKX39380.1 - 3.3e-07 29.6 0.1 1.2e-06 27.7 0.0 1.9 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 EKX39380.1 - 0.00048 20.2 0.4 0.0034 17.4 0.4 2.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 EKX39380.1 - 0.00054 19.9 0.1 0.2 11.5 0.1 2.4 1 1 1 2 2 2 1 NTPase Zeta_toxin PF06414.12 EKX39380.1 - 0.0011 18.3 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin VirC1 PF07015.11 EKX39380.1 - 0.0011 18.3 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 VirC1 protein AAA_24 PF13479.6 EKX39380.1 - 0.0022 17.7 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EKX39380.1 - 0.0025 18.1 0.0 0.0061 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EKX39380.1 - 0.0026 17.5 0.0 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EKX39380.1 - 0.0046 17.4 0.0 0.0068 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain SRP54_N PF02881.19 EKX39380.1 - 0.0084 16.3 0.0 0.028 14.7 0.0 1.9 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 EKX39380.1 - 0.011 16.0 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 EKX39380.1 - 0.011 15.3 1.0 0.024 14.1 0.0 1.8 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 EKX39380.1 - 0.011 15.0 0.6 0.44 9.7 0.3 2.2 2 0 0 2 2 2 0 Anion-transporting ATPase RsgA_GTPase PF03193.16 EKX39380.1 - 0.019 14.9 0.6 0.25 11.2 0.2 2.6 2 1 1 3 3 3 0 RsgA GTPase TPP_enzyme_M PF00205.22 EKX39380.1 - 0.02 14.6 0.1 0.14 11.9 0.0 2.4 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain NACHT PF05729.12 EKX39380.1 - 0.032 14.2 0.0 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 NACHT domain 6PF2K PF01591.18 EKX39380.1 - 0.06 12.6 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase PIF1 PF05970.14 EKX39380.1 - 0.063 12.4 0.0 0.076 12.2 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase MMR_HSR1 PF01926.23 EKX39380.1 - 0.07 13.2 0.4 0.49 10.5 0.4 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.6 EKX39380.1 - 0.13 12.7 0.0 0.31 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EKX39380.1 - 0.14 12.7 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 EKX39380.1 - 0.15 11.8 0.0 1.2 8.9 0.0 2.3 1 1 1 2 2 2 0 P-loop containing region of AAA domain SMC_N PF02463.19 EKX39380.1 - 0.16 11.4 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF778 PF05608.12 EKX39381.1 - 0.046 14.1 0.0 0.061 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF778) RPE65 PF03055.15 EKX39382.1 - 2e-65 221.8 0.0 2.2e-65 221.6 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein RCC1 PF00415.18 EKX39383.1 - 3.4e-68 226.1 24.2 2.8e-12 47.1 0.4 7.1 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX39383.1 - 3.7e-40 134.9 37.3 2.9e-09 36.5 1.8 7.0 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat MMR_HSR1 PF01926.23 EKX39384.1 - 2.9e-20 72.4 0.0 3.4e-20 72.2 0.0 1.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EKX39384.1 - 6.5e-07 29.5 0.2 0.018 15.1 0.0 2.1 1 1 1 2 2 2 2 Dynamin family FeoB_N PF02421.18 EKX39384.1 - 7.4e-06 25.6 0.0 8.2e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EKX39384.1 - 5.8e-05 23.0 0.0 0.00096 19.1 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EKX39384.1 - 0.00083 18.9 0.1 0.16 11.5 0.0 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain IIGP PF05049.13 EKX39384.1 - 0.0014 17.8 0.1 0.0023 17.1 0.1 1.3 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Septin PF00735.18 EKX39384.1 - 0.0069 15.7 0.2 0.3 10.3 0.1 2.5 1 1 1 2 2 2 1 Septin AAA_15 PF13175.6 EKX39384.1 - 0.008 15.9 0.0 0.0082 15.9 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EKX39384.1 - 0.011 16.2 0.1 0.012 16.1 0.1 1.3 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 EKX39384.1 - 0.045 14.0 0.1 0.085 13.1 0.1 1.8 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EKX39384.1 - 0.046 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRPRB PF09439.10 EKX39384.1 - 0.068 12.6 0.0 0.097 12.1 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 EKX39384.1 - 0.11 13.1 0.0 0.13 12.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain Rhodanese PF00581.20 EKX39386.1 - 2.6e-05 24.7 0.1 6e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 Rhodanese-like domain DHC_N1 PF08385.12 EKX39387.1 - 2.4e-184 614.1 5.8 2.4e-184 614.1 5.8 3.3 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 EKX39387.1 - 8.7e-138 458.8 3.1 1.5e-137 458.0 0.0 2.8 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EKX39387.1 - 1.1e-120 403.4 12.3 1.1e-120 403.4 12.3 4.8 6 1 1 7 7 4 1 Dynein heavy chain, N-terminal region 2 MT PF12777.7 EKX39387.1 - 3.2e-105 352.0 15.0 8.3e-105 350.6 15.0 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.7 EKX39387.1 - 2.6e-94 315.4 0.0 1.1e-93 313.3 0.0 2.2 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EKX39387.1 - 6.8e-87 291.5 0.6 2.1e-86 290.0 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EKX39387.1 - 1.9e-83 278.9 3.9 1.9e-83 278.9 3.9 2.9 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 EKX39387.1 - 3.3e-72 241.8 1.3 2e-67 226.2 0.2 4.1 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EKX39387.1 - 1.6e-46 158.1 0.0 4.2e-46 156.8 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EKX39387.1 - 6.7e-35 119.8 0.0 8.7e-34 116.2 0.0 3.0 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 EKX39387.1 - 5.9e-30 103.4 1.6 4.3e-29 100.7 0.7 3.0 2 0 0 2 2 2 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 EKX39387.1 - 4.7e-25 88.1 0.1 2e-24 86.1 0.1 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EKX39387.1 - 6.9e-23 81.2 0.0 7e-11 42.3 0.0 5.6 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA PF00004.29 EKX39387.1 - 1.1e-08 35.5 1.1 0.63 10.5 0.0 5.3 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EKX39387.1 - 2.6e-06 27.3 0.5 0.058 13.1 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 EKX39387.1 - 4.1e-06 27.4 0.9 0.5 10.9 0.0 4.7 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.6 EKX39387.1 - 4.5e-06 27.2 0.1 0.96 9.8 0.0 5.1 4 0 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 EKX39387.1 - 5.4e-06 26.7 0.5 4.4 7.6 0.0 5.2 4 0 0 4 4 4 1 AAA domain AAA_14 PF13173.6 EKX39387.1 - 5.1e-05 23.3 1.2 0.042 13.9 0.0 4.1 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 EKX39387.1 - 8.8e-05 22.8 0.1 0.41 11.0 0.0 4.1 3 0 0 3 3 3 1 RNA helicase AAA_19 PF13245.6 EKX39387.1 - 0.00025 21.4 0.4 0.99 9.7 0.0 4.1 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 EKX39387.1 - 0.0064 16.4 0.5 0.33 10.8 0.0 3.7 4 0 0 4 4 3 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 EKX39387.1 - 0.0066 16.4 0.0 4.8 7.1 0.0 3.0 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 EKX39387.1 - 0.007 16.9 0.9 1.1 9.8 0.0 3.7 3 0 0 3 3 2 1 ABC transporter Viral_helicase1 PF01443.18 EKX39387.1 - 0.0097 15.7 0.0 0.16 11.6 0.0 2.8 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 EKX39387.1 - 0.015 15.5 3.0 30 4.8 0.1 4.7 4 0 0 4 4 4 0 AAA domain Sigma54_activat PF00158.26 EKX39387.1 - 0.016 15.0 1.3 7.8 6.2 0.0 3.3 4 0 0 4 4 3 0 Sigma-54 interaction domain T2SSE PF00437.20 EKX39387.1 - 0.029 13.4 0.0 0.24 10.4 0.0 2.4 3 0 0 3 3 2 0 Type II/IV secretion system protein AAA_29 PF13555.6 EKX39387.1 - 0.042 13.6 0.1 29 4.5 0.0 3.6 3 0 0 3 3 3 0 P-loop containing region of AAA domain Roc PF08477.13 EKX39387.1 - 0.34 11.1 3.6 12 6.1 0.0 4.1 4 0 0 4 4 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 EKX39387.1 - 0.46 10.6 7.0 38 4.4 0.0 5.2 6 0 0 6 6 5 0 AAA domain TsaE PF02367.17 EKX39387.1 - 0.61 10.1 7.0 14 5.7 0.0 4.9 5 0 0 5 5 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ING PF12998.7 EKX39387.1 - 0.89 10.2 14.7 7.5 7.2 1.4 5.7 5 0 0 5 5 4 0 Inhibitor of growth proteins N-terminal histone-binding DUF1664 PF07889.12 EKX39387.1 - 0.91 9.6 30.1 2 8.5 0.1 8.6 8 1 1 9 9 8 0 Protein of unknown function (DUF1664) ATPase PF06745.13 EKX39387.1 - 1.5 8.1 5.1 13 5.0 0.0 3.8 4 0 0 4 4 3 0 KaiC ATP_bind_1 PF03029.17 EKX39387.1 - 3.9 7.2 11.3 1 9.1 0.1 3.9 5 0 0 5 5 3 0 Conserved hypothetical ATP binding protein Wzy_C PF04932.15 EKX39388.1 - 0.079 12.6 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 O-Antigen ligase DUF4131 PF13567.6 EKX39388.1 - 0.91 9.1 5.9 1.6 8.4 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Pkinase PF00069.25 EKX39389.1 - 8.3e-59 199.1 0.9 9.7e-59 198.9 0.9 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX39389.1 - 4.9e-42 144.0 0.4 5.8e-42 143.8 0.4 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX39389.1 - 1.2e-10 41.2 0.3 2.2e-09 37.1 0.0 2.3 2 1 1 3 3 3 1 Kinase-like APH PF01636.23 EKX39389.1 - 8.7e-05 22.5 0.0 0.13 12.1 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX39389.1 - 0.00088 18.2 0.1 0.0019 17.1 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase RecC_C PF17946.1 EKX39389.1 - 0.16 11.7 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 RecC C-terminal domain Glutaredoxin PF00462.24 EKX39391.1 - 6.4e-19 67.9 0.0 1.3e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Peptidase_M24 PF00557.24 EKX39392.1 - 3.4e-22 79.2 1.2 4.4e-22 78.8 1.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF4404 PF14357.6 EKX39392.1 - 0.87 10.3 0.0 0.87 10.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) TPR_20 PF14561.6 EKX39393.1 - 8.9e-19 67.6 0.2 5.5e-14 52.3 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat Thioredoxin PF00085.20 EKX39393.1 - 2.6e-05 24.1 0.1 7.4e-05 22.7 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin TPR_16 PF13432.6 EKX39393.1 - 0.013 16.1 1.0 19 6.0 0.0 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF1390 PF07150.11 EKX39393.1 - 0.019 14.7 0.1 0.047 13.4 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1390) Thioredoxin_6 PF13848.6 EKX39393.1 - 0.023 14.6 0.1 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like domain UCH PF00443.29 EKX39393.1 - 0.038 13.5 0.1 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase TPR_11 PF13414.6 EKX39393.1 - 0.062 13.0 0.1 11 5.8 0.0 3.5 4 0 0 4 4 4 0 TPR repeat TPR_2 PF07719.17 EKX39393.1 - 0.063 13.4 0.2 19 5.6 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX39393.1 - 0.21 12.5 2.7 16 6.6 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX39393.1 - 0.37 11.3 7.6 3.5 8.2 0.1 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Rotamase PF00639.21 EKX39394.1 - 7.3e-18 65.3 0.2 1.6e-17 64.2 0.2 1.6 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EKX39394.1 - 6.5e-12 46.0 0.1 2.1e-11 44.4 0.1 1.8 1 1 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 EKX39394.1 - 3.9e-10 39.6 3.2 8.9e-10 38.5 3.2 1.7 1 0 0 1 1 1 1 WW domain DSPc PF00782.20 EKX39394.1 - 7.3e-05 22.6 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rotamase_2 PF13145.6 EKX39394.1 - 0.00055 20.8 0.1 0.0014 19.4 0.0 1.8 2 0 0 2 2 2 1 PPIC-type PPIASE domain Y_phosphatase PF00102.27 EKX39394.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Sgf11 PF08209.11 EKX39398.1 - 1.8 8.2 4.0 4.1 7.1 4.0 1.6 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) LysM PF01476.20 EKX39399.1 - 0.00011 22.2 0.0 0.0006 19.8 0.0 2.2 2 0 0 2 2 2 1 LysM domain FAA_hydrolase_N PF09298.11 EKX39400.1 - 3.6 7.8 7.0 2.9 8.1 3.4 2.8 2 1 0 2 2 2 0 Fumarylacetoacetase N-terminal Pkinase PF00069.25 EKX39401.1 - 6.3e-70 235.5 0.0 7.6e-70 235.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX39401.1 - 4.4e-32 111.4 0.0 5.7e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX39401.1 - 3.6e-06 26.5 2.2 8.4e-06 25.3 2.2 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX39401.1 - 3.1e-05 24.0 0.1 0.15 11.9 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EKX39401.1 - 0.00027 20.0 0.3 0.00038 19.5 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 EKX39401.1 - 0.006 16.2 0.6 0.039 13.5 0.1 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 EKX39401.1 - 0.026 14.1 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kinase-like PF14531.6 EKX39401.1 - 0.066 12.5 0.4 0.22 10.8 0.0 1.8 2 1 0 2 2 2 0 Kinase-like EcKinase PF02958.20 EKX39401.1 - 0.12 11.6 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Spore-coat_CotD PF11122.8 EKX39401.1 - 0.16 12.8 0.0 0.59 11.0 0.0 1.8 2 0 0 2 2 2 0 Inner spore coat protein D WD40 PF00400.32 EKX39403.1 - 1.9e-25 88.6 18.5 9.2e-09 35.8 0.1 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX39403.1 - 5.9e-13 48.9 0.0 0.019 15.3 0.0 4.6 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EKX39403.1 - 0.086 11.4 0.0 0.15 10.5 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain WD40_like PF17005.5 EKX39403.1 - 0.1 11.9 0.0 7.1 5.9 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain Hira PF07569.11 EKX39403.1 - 0.21 11.3 0.6 0.83 9.3 0.1 2.2 2 1 1 3 3 3 0 TUP1-like enhancer of split Med11 PF10280.9 EKX39404.1 - 0.043 14.3 2.1 0.069 13.6 2.1 1.3 1 0 0 1 1 1 0 Mediator complex protein Vps54 PF07928.12 EKX39404.1 - 0.71 10.3 3.6 0.3 11.5 1.5 1.4 2 0 0 2 2 2 0 Vps54-like protein RCC1 PF00415.18 EKX39405.1 - 2.4e-42 143.3 29.5 6.6e-13 49.1 0.1 5.9 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX39405.1 - 4.2e-42 141.1 37.6 1e-09 38.0 0.4 5.8 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat DUF3659 PF12396.8 EKX39405.1 - 0.04 13.8 0.2 0.24 11.3 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) Kelch_6 PF13964.6 EKX39405.1 - 0.098 13.0 5.0 5 7.6 0.0 4.1 5 0 0 5 5 5 0 Kelch motif DUF1459 PF07312.11 EKX39405.1 - 5.8 7.2 16.5 4.8 7.5 0.5 4.4 4 1 1 5 5 5 0 Protein of unknown function (DUF1459) Patched PF02460.18 EKX39406.1 - 5e-82 276.3 7.1 5.5e-79 266.2 7.1 2.4 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 EKX39406.1 - 1.5e-33 115.8 7.8 1.5e-33 115.8 7.8 2.8 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation GWT1 PF06423.12 EKX39406.1 - 1.3 9.2 4.6 3.6 7.7 1.0 2.6 1 1 0 2 2 2 0 GWT1 Dynein_C PF18199.1 EKX39409.1 - 3.7e-11 42.8 0.0 4.3e-11 42.6 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain Colipase_C PF02740.14 EKX39409.1 - 0.048 13.8 0.1 0.096 12.9 0.1 1.4 1 0 0 1 1 1 0 Colipase, C-terminal domain Glyco_hydro_14 PF01373.17 EKX39410.1 - 2.9e-110 369.0 0.0 3.3e-110 368.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 PAPS_reduct PF01507.19 EKX39412.1 - 3.4e-25 89.1 0.3 9.8e-17 61.5 0.0 2.7 2 1 1 3 3 3 2 Phosphoadenosine phosphosulfate reductase family MoCF_biosynth PF00994.24 EKX39412.1 - 1.7e-23 82.9 0.1 3.3e-23 82.0 0.1 1.6 1 0 0 1 1 1 1 Probable molybdopterin binding domain DUF4481 PF14800.6 EKX39412.1 - 0.0067 15.9 0.3 0.014 14.9 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4481) Erp_C PF06780.11 EKX39412.1 - 0.29 11.1 1.0 13 5.7 0.1 2.7 3 0 0 3 3 3 0 Erp protein C-terminus Methyltransf_PK PF05891.12 EKX39413.1 - 2.5e-27 95.9 0.0 3.2e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_11 PF08241.12 EKX39413.1 - 2.4e-12 47.3 0.0 4.2e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX39413.1 - 7.7e-09 36.1 0.0 1.7e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX39413.1 - 0.00038 21.2 0.0 0.0008 20.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EKX39413.1 - 0.0035 16.7 0.0 0.006 15.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Rsm22 PF09243.10 EKX39413.1 - 0.0043 16.4 0.0 0.0061 15.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 DUF1179 PF06678.11 EKX39414.1 - 0.52 10.3 1.2 16 5.5 1.2 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1179) DEC-1_N PF04625.13 EKX39415.1 - 0.012 14.7 7.2 0.015 14.3 7.2 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region RRM_3 PF08777.11 EKX39415.1 - 1.2 9.3 5.5 2.1 8.4 1.4 2.1 2 0 0 2 2 2 0 RNA binding motif DUF5525 PF17663.1 EKX39415.1 - 1.8 6.5 13.7 2.4 6.1 13.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5525) zinc-ribbon_6 PF10005.9 EKX39416.1 - 0.0034 18.0 2.8 0.0056 17.3 2.8 1.4 1 0 0 1 1 1 1 zinc-ribbon domain PcfK PF14058.6 EKX39416.1 - 0.014 15.7 2.6 0.021 15.1 2.6 1.2 1 0 0 1 1 1 0 PcfK-like protein ICA69 PF04629.14 EKX39416.1 - 0.34 11.2 3.5 0.42 10.9 3.5 1.1 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain Cytomega_UL84 PF06284.11 EKX39416.1 - 8.3 4.7 6.6 10 4.4 6.6 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF4461 PF14688.6 EKX39418.1 - 9.1e-30 104.5 0.2 1.2e-29 104.1 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4461) DUF4460 PF14687.6 EKX39418.1 - 1.5e-16 60.4 0.1 3.3e-16 59.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) DnaJ PF00226.31 EKX39418.1 - 0.076 13.2 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 DnaJ domain DUF4685 PF15737.5 EKX39418.1 - 0.11 13.0 2.4 0.34 11.4 0.8 2.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4685) DUF58 PF01882.18 EKX39418.1 - 0.12 12.6 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF58 Myotub-related PF06602.14 EKX39419.1 - 1.3e-108 363.1 0.3 1.7e-108 362.7 0.3 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 EKX39419.1 - 0.00024 20.9 0.5 0.00062 19.6 0.5 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX39419.1 - 0.0036 16.9 0.1 0.0078 15.8 0.1 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EKX39419.1 - 0.14 12.1 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Thioredoxin PF00085.20 EKX39422.1 - 1.3e-11 44.4 0.2 3.4e-11 43.0 0.2 1.6 1 1 0 1 1 1 1 Thioredoxin Fer2 PF00111.27 EKX39422.1 - 0.069 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DUF953 PF06110.11 EKX39422.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_8 PF13905.6 EKX39422.1 - 0.16 12.3 0.1 9.7 6.6 0.3 2.2 1 1 1 2 2 2 0 Thioredoxin-like Aminotran_5 PF00266.19 EKX39424.1 - 2.1e-35 122.4 0.0 4.2e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V ATP_bind_3 PF01171.20 EKX39424.1 - 1.4e-17 64.0 0.0 2.6e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 PP-loop family BUD22 PF09073.10 EKX39425.1 - 1.2 8.4 45.4 1.6 7.9 45.4 1.3 1 0 0 1 1 1 0 BUD22 DUF3295 PF11702.8 EKX39425.1 - 2.5 7.4 30.0 3.2 7.0 30.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) PA26 PF04636.13 EKX39425.1 - 6.4 5.6 7.2 7.8 5.3 7.2 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) XRN_M PF17846.1 EKX39425.1 - 6.9 5.5 11.5 9.7 5.0 11.5 1.2 1 0 0 1 1 1 0 Xrn1 helical domain ABC_membrane PF00664.23 EKX39426.1 - 2e-72 244.1 24.7 6e-41 140.9 6.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EKX39426.1 - 1.2e-49 168.4 0.0 9e-32 110.5 0.0 3.7 2 1 1 3 3 3 3 ABC transporter SMC_N PF02463.19 EKX39426.1 - 2.3e-10 40.3 2.5 0.00024 20.6 0.1 4.0 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EKX39426.1 - 5.4e-05 23.2 0.9 6.3 6.5 0.0 4.5 4 1 1 5 5 5 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EKX39426.1 - 0.0002 21.4 0.3 0.049 13.7 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EKX39426.1 - 0.00069 20.0 0.2 0.1 13.0 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 EKX39426.1 - 0.00096 18.8 0.2 0.73 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EKX39426.1 - 0.0014 18.3 0.2 0.93 9.3 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 EKX39426.1 - 0.002 18.5 0.1 4.9 7.6 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EKX39426.1 - 0.002 18.7 0.2 1.9 8.9 0.2 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EKX39426.1 - 0.0026 17.7 0.5 0.13 12.2 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 EKX39426.1 - 0.0026 17.5 0.2 0.016 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EKX39426.1 - 0.0045 16.9 0.1 3.1 7.7 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase IstB_IS21 PF01695.17 EKX39426.1 - 0.0091 15.7 3.5 0.63 9.7 0.0 3.3 4 0 0 4 4 3 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 EKX39426.1 - 0.012 14.9 0.0 1 8.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 EKX39426.1 - 0.033 14.7 0.0 1.6 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 EKX39426.1 - 0.041 13.9 0.0 15 5.7 0.0 2.9 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NB-ARC PF00931.22 EKX39426.1 - 0.081 12.1 0.3 1.8 7.7 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain T2SSE PF00437.20 EKX39426.1 - 0.11 11.6 0.0 5.5 6.0 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.17 EKX39426.1 - 0.11 12.6 1.2 0.16 12.1 0.2 1.8 2 0 0 2 2 1 0 Helicase HerA, central domain AAA_7 PF12775.7 EKX39426.1 - 0.12 11.9 0.1 10 5.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 EKX39426.1 - 0.16 12.3 3.3 5.3 7.3 0.4 3.1 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EKX39426.1 - 0.18 11.6 0.9 6.3 6.5 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Bunya_G2 PF03563.13 EKX39426.1 - 0.23 10.7 1.2 15 4.7 0.0 2.3 2 0 0 2 2 2 0 Bunyavirus glycoprotein G2 cobW PF02492.19 EKX39426.1 - 0.31 10.6 4.1 0.59 9.7 0.0 2.6 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DEAD PF00270.29 EKX39426.1 - 1 9.1 5.7 7.8 6.2 2.2 3.2 2 2 0 2 2 2 0 DEAD/DEAH box helicase RRG8 PF17068.5 EKX39427.1 - 0.16 11.4 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Required for respiratory growth protein 8 mitochondrial ATP-synt_D PF01813.17 EKX39433.1 - 4.8e-68 228.9 5.0 6.1e-68 228.5 5.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit D DUF3337 PF11816.8 EKX39433.1 - 0.074 12.9 0.3 1.2 9.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3337) XhlA PF10779.9 EKX39433.1 - 5.8 7.2 8.7 1.6 9.0 3.8 2.4 2 0 0 2 2 2 0 Haemolysin XhlA Cep57_CLD PF14073.6 EKX39433.1 - 8.8 6.3 14.4 5.9 6.9 8.1 2.6 2 1 1 3 3 3 0 Centrosome localisation domain of Cep57 HSBP1 PF06825.12 EKX39434.1 - 7.9e-28 96.1 5.7 7.9e-28 96.1 5.7 1.4 2 0 0 2 2 2 1 Heat shock factor binding protein 1 BLOC1_2 PF10046.9 EKX39434.1 - 0.00027 21.2 3.2 0.029 14.7 0.3 1.6 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 EspB PF05802.11 EKX39434.1 - 0.0018 18.3 0.8 0.0018 18.3 0.8 1.3 1 1 0 1 1 1 1 Enterobacterial EspB protein CheZ PF04344.13 EKX39434.1 - 0.015 15.2 1.6 0.015 15.2 1.6 1.1 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ GAS PF13851.6 EKX39434.1 - 0.024 14.0 0.7 0.026 13.9 0.7 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Matrilin_ccoil PF10393.9 EKX39434.1 - 0.037 13.9 0.1 0.22 11.4 0.1 2.0 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin UPF0184 PF03670.13 EKX39434.1 - 0.045 14.2 0.8 0.053 13.9 0.8 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) CLZ PF16526.5 EKX39434.1 - 0.052 13.9 0.3 0.11 12.8 0.2 1.5 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Erythro-docking PF09277.11 EKX39434.1 - 0.054 13.4 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Erythronolide synthase, docking STAT_int PF02865.17 EKX39434.1 - 0.082 13.4 0.6 0.1 13.1 0.5 1.3 1 1 0 1 1 1 0 STAT protein, protein interaction domain IL11 PF07400.11 EKX39434.1 - 0.13 12.0 0.2 0.94 9.1 0.1 1.8 1 1 1 2 2 2 0 Interleukin 11 YvrJ PF12841.7 EKX39434.1 - 0.2 11.2 0.1 1.2 8.8 0.0 2.0 2 0 0 2 2 2 0 YvrJ protein family APG6_N PF17675.1 EKX39435.1 - 0.0018 18.8 0.9 0.0018 18.8 0.9 1.7 2 0 0 2 2 2 1 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 EKX39435.1 - 0.0035 17.3 1.6 0.0053 16.8 0.4 1.8 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SlyX PF04102.12 EKX39435.1 - 0.0048 17.5 1.5 0.02 15.5 0.9 2.2 2 0 0 2 2 2 1 SlyX DASH_Spc19 PF08287.11 EKX39435.1 - 0.0062 16.4 1.1 0.0062 16.4 1.1 2.1 2 1 0 2 2 2 1 Spc19 BRE1 PF08647.11 EKX39435.1 - 0.009 16.1 2.3 0.028 14.5 2.3 1.8 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase ZapB PF06005.12 EKX39435.1 - 0.01 16.2 4.1 0.017 15.5 2.7 1.9 2 0 0 2 2 2 0 Cell division protein ZapB CENP-Q PF13094.6 EKX39435.1 - 0.021 15.0 2.0 0.25 11.5 0.1 2.3 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Spc24 PF08286.11 EKX39435.1 - 0.026 14.8 1.4 0.083 13.1 0.6 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FapA PF03961.13 EKX39435.1 - 0.028 13.0 0.6 0.033 12.8 0.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc7 PF08317.11 EKX39435.1 - 0.042 12.7 1.1 0.11 11.3 0.5 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein HALZ PF02183.18 EKX39435.1 - 0.051 13.8 2.3 0.082 13.2 0.4 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper COG2 PF06148.11 EKX39435.1 - 0.077 13.1 0.4 0.24 11.5 0.2 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Suppressor_APC PF11414.8 EKX39435.1 - 0.094 12.8 0.6 0.26 11.4 0.2 1.9 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein Prefoldin_2 PF01920.20 EKX39435.1 - 0.11 12.5 3.5 0.3 11.1 3.5 1.6 1 0 0 1 1 1 0 Prefoldin subunit DEDD_Tnp_IS110 PF01548.17 EKX39435.1 - 0.22 11.4 1.4 0.89 9.4 1.4 1.9 1 1 0 1 1 1 0 Transposase PRKG1_interact PF15898.5 EKX39435.1 - 0.23 12.4 4.3 0.14 13.1 1.7 1.9 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain TMPIT PF07851.13 EKX39435.1 - 0.28 10.4 0.6 0.49 9.6 0.6 1.3 1 0 0 1 1 1 0 TMPIT-like protein Cluap1 PF10234.9 EKX39435.1 - 0.41 10.0 3.3 2.7 7.3 1.0 2.1 2 0 0 2 2 2 0 Clusterin-associated protein-1 DUF4164 PF13747.6 EKX39435.1 - 0.46 10.8 4.5 0.14 12.4 0.8 2.0 3 0 0 3 3 1 0 Domain of unknown function (DUF4164) JIP_LZII PF16471.5 EKX39435.1 - 0.65 10.2 3.5 0.79 9.9 2.1 1.8 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II SWIRM PF04433.17 EKX39436.1 - 0.062 13.6 0.3 0.23 11.8 0.3 2.1 1 0 0 1 1 1 0 SWIRM domain TMF_DNA_bd PF12329.8 EKX39436.1 - 0.36 10.9 10.7 0.11 12.5 6.2 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding BLOC1_2 PF10046.9 EKX39436.1 - 0.97 9.8 9.3 0.2 12.0 4.1 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CRR7 PF12095.8 EKX39436.1 - 1.7 9.2 7.6 15 6.2 0.4 3.0 2 1 1 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 Peptidase_C54 PF03416.19 EKX39437.1 - 2.7e-72 243.5 0.0 3.2e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.13 EKX39437.1 - 0.2 11.1 0.1 0.3 10.5 0.1 1.2 1 0 0 1 1 1 0 Peptidase family C78 Xan_ur_permease PF00860.20 EKX39438.1 - 2.5e-62 210.8 28.6 3.4e-62 210.4 28.6 1.2 1 0 0 1 1 1 1 Permease family YoqO PF14037.6 EKX39438.1 - 0.78 10.3 7.9 0.13 12.8 0.5 2.9 2 0 0 2 2 2 0 YoqO-like protein Glycos_transf_2 PF00535.26 EKX39440.1 - 0.0064 16.3 0.0 0.0097 15.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 2OG-FeII_Oxy_3 PF13640.6 EKX39441.1 - 2.1e-16 60.6 0.0 3.5e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ShK PF01549.24 EKX39441.1 - 4.6e-06 27.1 8.5 4.6e-06 27.1 8.5 1.6 2 0 0 2 2 2 1 ShK domain-like 2OG-FeII_Oxy PF03171.20 EKX39441.1 - 8e-05 23.1 0.1 0.00031 21.2 0.0 1.9 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 EKX39441.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus C4/C10 protein adh_short PF00106.25 EKX39442.1 - 3.9e-14 52.6 0.3 5.3e-13 48.9 0.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EKX39442.1 - 4.1e-10 39.6 0.0 4.9e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX39442.1 - 7.1e-08 32.6 0.0 9.3e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 KR domain EF-hand_6 PF13405.6 EKX39443.1 - 0.0022 17.8 0.3 0.011 15.6 0.3 2.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 EKX39443.1 - 0.0078 15.7 0.5 0.029 13.9 0.3 2.1 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EKX39443.1 - 0.016 15.6 0.1 0.089 13.3 0.1 2.3 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 EKX39443.1 - 0.02 14.4 0.2 0.069 12.7 0.2 1.9 1 0 0 1 1 1 0 EF hand GAS PF13851.6 EKX39443.1 - 0.14 11.5 46.7 2 7.7 5.1 3.5 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 EKX39443.1 - 2.6 8.7 34.6 1.5 9.5 2.3 4.5 2 1 2 4 4 4 0 Initiation control protein YabA Jnk-SapK_ap_N PF09744.9 EKX39443.1 - 2.9 8.1 38.0 0.58 10.4 3.4 3.3 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 DUF2400 PF09674.10 EKX39443.1 - 5 7.0 9.5 8.3 6.3 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) PPARgamma_N PF12577.8 EKX39444.1 - 0.085 13.5 0.1 0.17 12.5 0.1 1.5 1 0 0 1 1 1 0 PPAR gamma N-terminal region LisH_2 PF16045.5 EKX39445.1 - 1.3e-07 30.5 0.0 2.2e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 LisH LisH PF08513.11 EKX39445.1 - 1.5e-05 24.7 0.9 4.4e-05 23.3 0.0 2.4 3 0 0 3 3 3 1 LisH DNA_ligase_ZBD PF03119.16 EKX39445.1 - 0.059 13.4 1.2 1.1 9.4 0.1 4.1 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Mpv17_PMP22 PF04117.12 EKX39446.1 - 3.2e-10 40.1 0.1 7.4e-10 38.9 0.1 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Polyketide_cyc2 PF10604.9 EKX39447.1 - 3.9e-05 24.0 0.4 5.2e-05 23.5 0.4 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DDA1 PF10172.9 EKX39449.1 - 2.9e-07 30.7 0.0 3.9e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Det1 complexing ubiquitin ligase WD40 PF00400.32 EKX39452.1 - 0.0062 17.4 5.9 1.9 9.5 0.0 3.6 3 1 0 3 3 3 2 WD domain, G-beta repeat Pkinase PF00069.25 EKX39453.1 - 2.3e-64 217.3 0.0 2.6e-64 217.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX39453.1 - 9.5e-39 133.2 0.0 1.1e-38 133.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX39453.1 - 1.4e-05 25.2 0.1 2.3e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EKX39453.1 - 0.00093 18.2 0.1 0.0012 17.8 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EKX39453.1 - 0.0032 16.8 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EKX39453.1 - 0.0066 15.3 0.0 0.009 14.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EKX39453.1 - 0.09 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 EKX39453.1 - 0.12 11.9 0.1 0.3 10.7 0.1 1.7 2 0 0 2 2 2 0 RIO1 family PDZ_6 PF17820.1 EKX39454.1 - 0.0031 17.3 0.0 0.0087 15.9 0.0 1.8 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX39454.1 - 0.015 15.3 0.1 0.043 13.8 0.0 1.8 2 0 0 2 2 2 0 Tricorn protease PDZ domain VCX_VCY PF15231.6 EKX39454.1 - 0.017 15.8 1.4 0.03 15.0 1.4 1.3 1 0 0 1 1 1 0 Variable charge X/Y family Snapin_Pallidin PF14712.6 EKX39454.1 - 0.022 15.2 6.6 0.042 14.3 6.1 1.7 1 1 0 1 1 1 0 Snapin/Pallidin DUF1664 PF07889.12 EKX39454.1 - 0.25 11.4 6.3 0.073 13.1 2.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PVL_ORF50 PF07768.11 EKX39454.1 - 0.89 9.9 8.1 3.1 8.2 5.7 2.3 2 0 0 2 2 2 0 PVL ORF-50-like family ATG16 PF08614.11 EKX39454.1 - 0.95 9.6 25.0 1.5 9.0 25.0 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) FapA PF03961.13 EKX39454.1 - 1.2 7.7 8.1 1.6 7.3 8.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A HALZ PF02183.18 EKX39454.1 - 1.6 9.0 9.2 1.6 9.0 2.1 3.3 3 1 0 3 3 3 0 Homeobox associated leucine zipper SPRY PF00622.28 EKX39455.1 - 2.5e-13 50.2 0.1 4.4e-13 49.4 0.1 1.4 1 0 0 1 1 1 1 SPRY domain Bt_P21 PF05560.11 EKX39455.1 - 0.00019 21.1 0.0 0.00054 19.6 0.0 1.7 2 0 0 2 2 2 1 Bacillus thuringiensis P21 molecular chaperone protein F-box PF00646.33 EKX39455.1 - 0.0004 20.2 2.3 0.0011 18.8 2.3 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EKX39455.1 - 1 9.3 3.5 0.52 10.2 0.2 2.2 2 0 0 2 2 2 0 F-box-like TRAP_alpha PF03896.16 EKX39456.1 - 3.2e-30 105.3 0.3 3.9e-30 105.0 0.3 1.0 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Wzt_C PF14524.6 EKX39456.1 - 0.028 14.5 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Wzt C-terminal domain MitoNEET_N PF10660.9 EKX39456.1 - 0.089 12.8 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus OAD_gamma PF04277.13 EKX39457.1 - 0.013 16.1 0.4 0.013 16.0 0.4 1.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain WD40 PF00400.32 EKX39460.1 - 1.1e-14 54.5 13.4 1.6e-07 31.9 0.5 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX39460.1 - 1.4e-05 25.3 0.3 0.31 11.4 0.0 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain TOBE_2 PF08402.10 EKX39460.1 - 0.0026 17.9 0.0 0.023 14.9 0.0 2.5 2 1 0 2 2 2 1 TOBE domain Cse1 PF08506.10 EKX39461.1 - 6.5e-104 347.7 1.2 1.6e-103 346.4 1.2 1.7 1 1 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 EKX39461.1 - 2e-82 277.1 2.7 2e-82 277.1 2.7 1.7 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 EKX39461.1 - 4.2e-12 45.8 0.1 1.7e-11 43.9 0.1 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Sec7_N PF12783.7 EKX39461.1 - 0.0045 16.9 4.1 1.2 9.0 0.5 4.5 3 1 1 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal MMS19_N PF14500.6 EKX39461.1 - 0.021 14.4 2.0 0.11 12.0 0.1 3.0 4 0 0 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II V-ATPase_H_N PF03224.14 EKX39461.1 - 0.078 12.2 0.8 0.2 10.9 0.1 2.1 2 0 0 2 2 2 0 V-ATPase subunit H HEAT PF02985.22 EKX39461.1 - 0.25 11.7 2.0 0.88 10.0 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat MMS19_C PF12460.8 EKX39461.1 - 0.43 9.6 7.2 0.38 9.8 0.1 2.9 2 1 0 2 2 2 0 RNAPII transcription regulator C-terminal cNMP_binding PF00027.29 EKX39462.1 - 3.2e-13 49.6 0.0 7.9e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain C2 PF00168.30 EKX39462.1 - 1.1e-07 32.1 0.0 3.4e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 C2 domain IQ PF00612.27 EKX39462.1 - 0.01 15.6 0.7 0.01 15.6 0.7 2.2 2 0 0 2 2 2 1 IQ calmodulin-binding motif Cation_ATPase_N PF00690.26 EKX39462.1 - 0.035 13.8 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Ion_trans PF00520.31 EKX39462.1 - 0.074 12.3 7.3 0.027 13.7 1.6 2.2 2 0 0 2 2 2 0 Ion transport protein TBCC PF07986.12 EKX39463.1 - 1.4e-37 128.0 5.3 2.5e-37 127.3 5.3 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 EKX39463.1 - 4.8e-06 26.3 0.3 1.1e-05 25.1 0.3 1.6 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Pex2_Pex12 PF04757.14 EKX39464.1 - 2.4e-25 89.5 0.0 3.1e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region Rnk_N PF14760.6 EKX39464.1 - 0.11 13.0 3.4 0.18 12.3 0.1 2.6 2 1 0 2 2 2 0 Rnk N-terminus Kelch_4 PF13418.6 EKX39468.1 - 2.1e-21 75.7 3.1 2.9e-05 24.0 0.0 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EKX39468.1 - 2.8e-20 71.9 0.0 7.8e-06 25.8 0.0 5.8 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 EKX39468.1 - 2e-15 56.1 0.5 4.8e-07 29.3 0.4 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 EKX39468.1 - 2.7e-14 53.0 6.8 1.4e-07 31.6 0.2 6.3 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 EKX39468.1 - 1.3e-08 34.5 4.3 0.11 12.5 0.2 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 EKX39468.1 - 1.4e-08 34.7 6.3 0.0056 16.9 0.0 4.9 4 1 1 5 5 5 2 Kelch motif SPX PF03105.19 EKX39468.1 - 0.00014 21.9 3.1 0.00019 21.5 3.1 1.2 1 0 0 1 1 1 1 SPX domain Secretin_N_2 PF07655.13 EKX39468.1 - 0.025 15.1 17.2 0.025 15.1 17.2 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain RAG2 PF03089.14 EKX39468.1 - 0.028 13.4 0.0 11 4.9 0.0 3.2 3 0 0 3 3 3 0 Recombination activating protein 2 AAA_6 PF12774.7 EKX39469.1 - 3.5e-130 433.8 0.1 3.8e-129 430.4 0.0 3.0 4 0 0 4 4 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EKX39469.1 - 6.7e-103 344.9 4.3 6.7e-103 344.9 4.3 6.0 4 2 0 5 5 1 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EKX39469.1 - 2.5e-68 229.5 5.7 2.5e-68 229.5 5.7 4.9 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 EKX39469.1 - 5.1e-55 186.6 0.0 5.8e-53 179.9 0.0 3.5 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 Dynein_heavy PF03028.15 EKX39469.1 - 1.8e-37 128.0 0.2 2.7e-36 124.3 0.0 3.2 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 EKX39469.1 - 4.5e-37 127.1 0.0 1.2e-21 77.1 0.0 6.3 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) MT PF12777.7 EKX39469.1 - 2.4e-33 115.6 8.5 7.6e-33 114.0 8.5 1.9 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 EKX39469.1 - 1.1e-32 113.5 0.3 5.9e-32 111.1 0.3 2.4 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 EKX39469.1 - 2e-32 112.2 0.0 8.8e-32 110.2 0.0 2.1 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_7 PF12775.7 EKX39469.1 - 3.4e-30 104.9 0.4 1.8e-25 89.5 0.0 3.5 3 0 0 3 3 3 2 P-loop containing dynein motor region DHC_N1 PF08385.12 EKX39469.1 - 7.9e-21 74.3 15.2 7.9e-21 74.3 15.2 3.8 6 2 0 6 6 3 1 Dynein heavy chain, N-terminal region 1 AAA_16 PF13191.6 EKX39469.1 - 4.2e-14 53.3 0.9 0.0097 16.3 0.0 6.7 6 1 0 7 7 5 3 AAA ATPase domain AAA_22 PF13401.6 EKX39469.1 - 4.6e-12 46.4 8.4 0.0091 16.3 0.0 7.9 9 0 0 9 9 6 2 AAA domain ABC_tran PF00005.27 EKX39469.1 - 1.6e-08 35.2 6.9 0.00057 20.4 0.0 5.4 4 0 0 4 4 3 2 ABC transporter AAA PF00004.29 EKX39469.1 - 2.9e-08 34.2 0.0 0.2 12.1 0.0 4.7 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EKX39469.1 - 3.1e-08 33.6 0.0 0.0034 17.1 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 EKX39469.1 - 1.1e-06 28.3 0.0 0.027 14.2 0.0 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_24 PF13479.6 EKX39469.1 - 4.2e-06 26.6 0.0 0.24 11.1 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 EKX39469.1 - 9.5e-06 25.8 0.7 0.44 10.7 0.0 4.1 4 0 0 4 4 3 2 AAA domain AAA_28 PF13521.6 EKX39469.1 - 1.1e-05 25.8 0.0 0.026 14.8 0.0 3.9 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EKX39469.1 - 1.3e-05 25.5 0.0 1.2 9.6 0.0 3.8 3 0 0 3 3 3 1 RNA helicase AAA_18 PF13238.6 EKX39469.1 - 3.1e-05 24.5 0.0 0.41 11.2 0.0 5.3 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 EKX39469.1 - 5.8e-05 23.1 0.1 0.69 9.8 0.0 4.0 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_21 PF13304.6 EKX39469.1 - 0.00014 21.7 0.0 0.0026 17.6 0.0 3.2 3 0 0 3 3 2 1 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 EKX39469.1 - 0.00024 21.1 0.0 0.13 12.1 0.0 3.8 3 0 0 3 3 3 1 NACHT domain AAA_14 PF13173.6 EKX39469.1 - 0.00026 21.0 0.0 1.6 8.8 0.0 4.6 4 0 0 4 4 3 1 AAA domain CbiA PF01656.23 EKX39469.1 - 0.0003 20.8 0.0 5.4 7.1 0.0 3.9 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain Laminin_I PF06008.14 EKX39469.1 - 0.00032 20.5 3.7 0.00032 20.5 3.7 6.7 6 0 0 6 6 5 1 Laminin Domain I IstB_IS21 PF01695.17 EKX39469.1 - 0.00058 19.6 0.1 6 6.6 0.0 4.4 5 0 0 5 5 3 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 EKX39469.1 - 0.0014 18.6 0.0 0.0014 18.6 0.0 5.1 5 0 0 5 5 4 1 RsgA GTPase cobW PF02492.19 EKX39469.1 - 0.0029 17.2 0.1 2.5 7.7 0.0 2.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 EKX39469.1 - 0.003 16.7 1.2 0.13 11.3 0.0 3.2 3 0 0 3 3 3 1 Type II/IV secretion system protein DUF815 PF05673.13 EKX39469.1 - 0.0031 16.7 0.0 0.53 9.4 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 EKX39469.1 - 0.0033 17.8 0.0 5.5 7.3 0.0 4.2 4 0 0 4 4 3 0 AAA domain ATP_bind_1 PF03029.17 EKX39469.1 - 0.0043 16.9 1.3 3.9 7.2 0.0 4.4 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein Adeno_IVa2 PF02456.15 EKX39469.1 - 0.0047 15.8 0.0 0.12 11.2 0.0 2.6 2 0 0 2 2 2 1 Adenovirus IVa2 protein MMR_HSR1 PF01926.23 EKX39469.1 - 0.0082 16.2 0.0 2.3 8.3 0.0 3.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Mg_chelatase PF01078.21 EKX39469.1 - 0.017 14.5 0.2 0.86 8.9 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_lid_1 PF17857.1 EKX39469.1 - 0.043 14.0 1.2 0.23 11.7 0.1 2.9 2 0 0 2 2 1 0 AAA+ lid domain PRK PF00485.18 EKX39469.1 - 0.051 13.3 0.0 4 7.1 0.0 2.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.6 EKX39469.1 - 0.054 14.0 0.0 0.054 14.0 0.0 9.6 8 2 0 8 8 4 0 AAA domain Gtr1_RagA PF04670.12 EKX39469.1 - 0.057 12.8 1.1 8 5.7 0.0 4.1 4 0 0 4 4 4 0 Gtr1/RagA G protein conserved region AAA_25 PF13481.6 EKX39469.1 - 0.058 13.0 0.0 17 4.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 EKX39469.1 - 0.07 13.3 0.0 16 5.8 0.0 3.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Viral_helicase1 PF01443.18 EKX39469.1 - 0.12 12.1 0.0 9.3 5.9 0.0 2.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Trans_reg_C PF00486.28 EKX39469.1 - 0.13 12.3 1.0 0.53 10.4 0.3 2.4 2 0 0 2 2 1 0 Transcriptional regulatory protein, C terminal Flagellin_C PF00700.21 EKX39469.1 - 0.14 12.6 6.4 0.29 11.5 2.1 3.2 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region ATPase_2 PF01637.18 EKX39469.1 - 0.14 12.0 13.4 1.4 8.8 0.0 5.1 6 0 0 6 6 3 0 ATPase domain predominantly from Archaea Fer4_NifH PF00142.18 EKX39469.1 - 0.15 11.5 0.1 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DASH_Dam1 PF08653.10 EKX39469.1 - 0.58 10.0 4.1 2e+02 1.9 0.0 6.3 6 0 0 6 6 4 0 DASH complex subunit Dam1 UbiA PF01040.18 EKX39470.1 - 6.2e-47 160.0 15.8 8.4e-47 159.6 15.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family RRM_1 PF00076.22 EKX39471.1 - 0.0073 16.1 0.0 21 5.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 EKX39472.1 - 6.2e-18 64.8 7.0 5.3e-05 23.9 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 EKX39472.1 - 0.12 10.9 1.7 2.5 6.6 0.0 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Corona_S2 PF01601.16 EKX39474.1 - 0.77 8.2 2.8 1 7.8 2.8 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein PDZ_6 PF17820.1 EKX39475.1 - 1.7e-15 56.6 0.0 4.2e-07 29.7 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 EKX39475.1 - 1.1e-13 51.3 0.1 1.5e-05 25.2 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX39475.1 - 2.2e-08 34.3 0.1 0.0024 18.1 0.1 2.6 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 EKX39475.1 - 0.00023 21.1 0.1 0.014 15.4 0.0 2.7 2 0 0 2 2 2 1 Tricorn protease PDZ domain Borrelia_P83 PF05262.11 EKX39475.1 - 0.01 14.4 11.1 0.013 14.0 11.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CDC45 PF02724.14 EKX39475.1 - 0.72 8.1 13.1 0.95 7.7 13.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 EKX39475.1 - 0.76 9.6 14.9 1.2 8.9 14.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF966 PF06136.13 EKX39475.1 - 0.83 9.3 9.0 1.3 8.7 9.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DDRGK PF09756.9 EKX39475.1 - 1.7 8.2 26.0 3.1 7.3 26.0 1.4 1 0 0 1 1 1 0 DDRGK domain Asp-B-Hydro_N PF05279.11 EKX39475.1 - 4.8 7.2 18.9 7.9 6.5 18.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Hydin_ADK PF17213.3 EKX39475.1 - 7.9 6.7 8.3 15 5.8 8.3 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain tRNA_int_end_N2 PF12928.7 EKX39476.1 - 4.4e-12 46.0 0.0 8e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term EF-hand_6 PF13405.6 EKX39477.1 - 1.2e-09 37.3 0.5 0.0056 16.5 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 EKX39477.1 - 2.1e-09 36.3 3.4 0.029 13.9 0.0 5.1 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.6 EKX39477.1 - 8.1e-08 32.6 1.5 0.0097 16.3 0.0 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 EKX39477.1 - 0.00011 22.4 0.0 0.00064 20.0 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain RabGAP-TBC PF00566.18 EKX39478.1 - 5e-07 29.6 0.1 5e-07 29.6 0.1 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain WD40 PF00400.32 EKX39478.1 - 2.1e-05 25.2 4.4 0.013 16.3 0.1 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX39478.1 - 0.00031 21.0 0.5 6.2 7.2 0.1 4.9 2 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain DUF2570 PF10828.8 EKX39479.1 - 0.091 12.6 6.3 0.13 12.1 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Pinin_SDK_memA PF04696.13 EKX39479.1 - 0.4 10.7 13.9 0.53 10.3 13.9 1.2 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region V_ATPase_I PF01496.19 EKX39479.1 - 2.6 5.8 7.0 2.8 5.8 7.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Metal_resist PF13801.6 EKX39479.1 - 4.4 7.5 10.4 2.4 8.3 6.6 1.9 1 1 1 2 2 2 0 Heavy-metal resistance NT-C2 PF10358.9 EKX39480.1 - 2e-10 40.6 0.6 3e-10 40.0 0.6 1.3 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Rrp44_CSD1 PF17216.3 EKX39480.1 - 0.027 14.2 0.1 0.034 13.9 0.1 1.2 1 0 0 1 1 1 0 Rrp44-like cold shock domain Na_trans_assoc PF06512.13 EKX39480.1 - 0.069 13.4 4.1 0.085 13.1 4.1 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated TLD PF07534.16 EKX39481.1 - 0.0004 20.6 0.0 0.00047 20.4 0.0 1.1 1 0 0 1 1 1 1 TLD Voldacs PF03517.13 EKX39482.1 - 0.091 12.9 0.5 8.1 6.6 0.5 2.2 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling FAM176 PF14851.6 EKX39482.1 - 0.22 11.2 4.2 0.17 11.5 0.6 2.0 2 0 0 2 2 2 0 FAM176 family DUF719 PF05334.13 EKX39482.1 - 0.7 10.1 2.9 1.3 9.2 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF719) E7 PF00527.18 EKX39482.1 - 3.2 8.0 6.6 39 4.5 3.7 2.4 2 0 0 2 2 2 0 E7 protein, Early protein DUF1761 PF08570.10 EKX39483.1 - 0.6 10.4 6.0 6.9 7.0 3.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1761) Methyltransf_32 PF13679.6 EKX39484.1 - 1.1e-11 45.0 1.0 7.9e-10 38.9 0.4 3.0 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX39484.1 - 1.7e-05 24.7 0.0 3.2e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EKX39484.1 - 4.4e-05 23.1 0.0 0.00023 20.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EKX39484.1 - 0.0023 18.6 0.0 0.0055 17.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain TRM13 PF05206.14 EKX39484.1 - 0.0037 16.8 3.1 0.034 13.7 3.1 2.2 1 1 0 1 1 1 1 Methyltransferase TRM13 Ubie_methyltran PF01209.18 EKX39484.1 - 0.16 11.2 0.0 0.33 10.2 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family HECT PF00632.25 EKX39486.1 - 1.9e-43 149.1 0.0 6.5e-42 144.1 0.0 2.7 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Mito_carr PF00153.27 EKX39486.1 - 1.1e-09 38.1 0.0 2.2e-06 27.5 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial carrier protein ADK PF00406.22 EKX39486.1 - 0.098 12.8 0.0 5 7.2 0.0 2.4 2 0 0 2 2 2 0 Adenylate kinase GTA_holin_3TM PF11351.8 EKX39486.1 - 0.15 12.6 0.0 0.42 11.1 0.0 1.7 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release fn3 PF00041.21 EKX39488.1 - 2.8e-22 78.8 0.7 1.2e-08 35.2 0.0 4.7 3 1 0 3 3 3 3 Fibronectin type III domain SRCR PF00530.18 EKX39488.1 - 9.3e-10 38.9 4.0 2.8e-09 37.4 4.0 1.8 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain DUF4215 PF13948.6 EKX39488.1 - 0.00016 22.0 3.2 0.00016 22.0 3.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4215) C2 PF00168.30 EKX39488.1 - 0.00017 21.8 0.0 0.0004 20.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain Y_phosphatase3 PF13350.6 EKX39489.1 - 2.2e-32 112.9 0.0 5.8e-32 111.5 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EKX39489.1 - 0.00018 21.2 0.0 0.00034 20.2 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF4574 PF15141.6 EKX39490.1 - 0.088 12.7 0.2 0.17 11.8 0.2 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 PUB PF09409.10 EKX39491.1 - 1.1e-17 63.7 0.0 8e-17 61.0 0.0 2.2 2 0 0 2 2 2 1 PUB domain UBA PF00627.31 EKX39491.1 - 1.6e-07 31.1 0.5 1.9e-06 27.6 0.0 2.8 3 0 0 3 3 3 1 UBA/TS-N domain FeoA PF04023.14 EKX39491.1 - 0.035 14.4 1.4 3.1 8.1 0.1 2.5 2 0 0 2 2 2 0 FeoA domain Fe-ADH PF00465.19 EKX39491.1 - 0.17 10.6 0.1 3.5 6.3 0.0 2.4 1 1 0 2 2 2 0 Iron-containing alcohol dehydrogenase Fmp27_WPPW PF10359.9 EKX39491.1 - 1.1 8.0 11.4 1.5 7.5 11.4 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain FapA PF03961.13 EKX39491.1 - 1.6 7.3 9.9 2 6.9 9.9 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Hid1 PF12722.7 EKX39491.1 - 9.3 4.2 8.1 11 4.0 8.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LRR_9 PF14580.6 EKX39492.1 - 7.6e-14 51.6 1.2 4.4e-11 42.6 0.4 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 EKX39492.1 - 2.8e-09 37.1 8.8 8.4e-05 22.9 0.4 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX39492.1 - 1.2e-05 24.9 11.7 0.00015 21.4 2.3 2.8 2 1 1 3 3 3 2 Leucine rich repeat cNMP_binding PF00027.29 EKX39493.1 - 0.001 19.1 0.2 0.19 11.8 0.0 2.7 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain DSPc PF00782.20 EKX39494.1 - 3.2e-32 111.2 0.0 4.7e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX39494.1 - 0.056 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase RVT_1 PF00078.27 EKX39496.1 - 4.8e-08 32.8 0.0 1.9e-05 24.3 0.0 2.2 1 1 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) ORC5_C PF14630.6 EKX39496.1 - 0.0099 15.4 0.2 0.016 14.8 0.2 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus Pkinase PF00069.25 EKX39499.1 - 5.4e-15 55.5 0.0 6.2e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX39499.1 - 2.6e-08 33.5 0.0 3.3e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX39499.1 - 0.019 14.3 0.0 0.022 14.1 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Peptidase_M76 PF09768.9 EKX39502.1 - 1.7e-63 213.4 3.3 1.9e-63 213.3 3.3 1.0 1 0 0 1 1 1 1 Peptidase M76 family Peptidase_M13 PF01431.21 EKX39502.1 - 0.086 12.4 0.2 0.12 11.9 0.2 1.2 1 0 0 1 1 1 0 Peptidase family M13 PDZ_6 PF17820.1 EKX39503.1 - 3.1e-05 23.7 0.3 0.00014 21.6 0.1 2.3 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX39503.1 - 0.035 14.4 0.1 0.58 10.5 0.0 2.6 2 0 0 2 2 2 0 PDZ domain DUF3337 PF11816.8 EKX39503.1 - 1.9 8.3 6.4 17 5.2 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3337) G-patch PF01585.23 EKX39504.1 - 0.00071 19.4 0.8 0.0015 18.4 0.8 1.6 1 0 0 1 1 1 1 G-patch domain HPP PF04982.13 EKX39506.1 - 1.3e-26 93.2 9.6 2.5e-26 92.2 9.6 1.5 1 0 0 1 1 1 1 HPP family Transgly_assoc PF04226.13 EKX39506.1 - 0.28 11.5 3.6 0.83 10.0 0.8 2.5 2 0 0 2 2 2 0 Transglycosylase associated protein Ion_trans PF00520.31 EKX39507.1 - 4.3e-24 85.1 20.4 2.6e-23 82.5 20.4 1.9 1 1 0 1 1 1 1 Ion transport protein PH PF00169.29 EKX39507.1 - 4.1e-05 24.0 0.6 0.00025 21.5 0.6 2.0 1 1 0 1 1 1 1 PH domain EF-hand_6 PF13405.6 EKX39507.1 - 0.00014 21.5 0.1 0.008 16.0 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain PH_3 PF14593.6 EKX39507.1 - 0.0014 18.7 0.2 1.2 9.2 0.0 2.3 2 0 0 2 2 2 2 PH domain EF-hand_1 PF00036.32 EKX39507.1 - 0.0017 17.8 0.1 0.015 14.8 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EKX39507.1 - 0.0096 15.7 0.2 0.045 13.6 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair PH_15 PF17339.2 EKX39507.1 - 0.023 14.6 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 PH domain EF-hand_7 PF13499.6 EKX39507.1 - 0.032 14.7 3.0 0.29 11.6 0.2 2.9 2 1 1 3 3 3 0 EF-hand domain pair EF-hand_5 PF13202.6 EKX39507.1 - 0.08 12.5 0.0 0.31 10.6 0.0 2.0 1 0 0 1 1 1 0 EF hand PKD_channel PF08016.12 EKX39507.1 - 3.8 6.1 19.6 1.5 7.4 8.8 3.6 2 1 0 3 3 3 0 Polycystin cation channel TRIC PF05197.13 EKX39508.1 - 0.021 14.4 2.4 0.27 10.8 1.3 2.7 1 1 1 2 2 2 0 TRIC channel RVP_2 PF08284.11 EKX39508.1 - 0.046 13.5 0.0 0.1 12.4 0.0 1.5 2 0 0 2 2 2 0 Retroviral aspartyl protease WD40 PF00400.32 EKX39509.1 - 1.4e-16 60.6 10.3 1.5e-07 32.0 0.1 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 EKX39509.1 - 0.0035 16.1 0.1 0.011 14.6 0.0 1.8 2 0 0 2 2 2 1 Nup133 N terminal like ANAPC4_WD40 PF12894.7 EKX39509.1 - 0.0059 16.9 0.3 5.3 7.4 0.0 3.0 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 EKX39509.1 - 0.01 15.6 5.8 5.5 6.7 0.1 3.8 3 1 1 4 4 4 0 TUP1-like enhancer of split Nup160 PF11715.8 EKX39509.1 - 0.017 13.8 0.3 0.042 12.5 0.1 1.9 2 0 0 2 2 2 0 Nucleoporin Nup120/160 XG_FTase PF03254.13 EKX39511.1 - 0.0031 16.2 0.4 0.0047 15.6 0.0 1.4 2 0 0 2 2 2 1 Xyloglucan fucosyltransferase Glyco_hydro38C2 PF17677.1 EKX39511.1 - 0.14 12.3 0.0 8.1 6.6 0.0 2.4 2 0 0 2 2 2 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain FAD_binding_3 PF01494.19 EKX39512.1 - 1.7e-12 47.3 0.0 1.2e-11 44.5 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 EKX39512.1 - 0.0054 15.8 0.0 0.0087 15.1 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Peroxin-3 PF04882.12 EKX39514.1 - 1.8e-07 30.5 7.1 6.7e-05 22.1 0.4 2.1 1 1 1 2 2 2 2 Peroxin-3 Syntaxin PF00804.25 EKX39514.1 - 0.026 14.2 7.4 0.13 11.9 0.5 3.0 3 0 0 3 3 3 0 Syntaxin DUF2063 PF09836.9 EKX39514.1 - 0.12 12.6 0.1 0.41 10.9 0.0 1.9 2 0 0 2 2 2 0 Putative DNA-binding domain DUF5321 PF17254.2 EKX39514.1 - 0.45 10.0 3.0 2.4 7.6 2.5 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5321) Hydrolase_4 PF12146.8 EKX39515.1 - 4.2e-09 36.0 0.0 6e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EKX39515.1 - 3.8e-08 33.3 0.0 6.2e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EKX39515.1 - 1.4e-06 29.1 0.0 2.6e-06 28.2 0.0 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EKX39515.1 - 0.001 18.9 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 EKX39515.1 - 0.0012 18.8 0.0 0.0027 17.6 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EKX39515.1 - 0.0037 17.1 0.0 0.0063 16.3 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.20 EKX39515.1 - 0.017 14.8 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 EKX39515.1 - 0.022 14.6 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.12 EKX39515.1 - 0.062 12.0 0.1 0.14 10.8 0.1 1.5 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_5 PF12695.7 EKX39515.1 - 0.084 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EKX39515.1 - 0.13 11.8 0.1 0.36 10.3 0.1 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family Thioesterase PF00975.20 EKX39515.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Virulence_fact PF13769.6 EKX39516.1 - 0.24 11.6 5.4 1.8 8.9 0.5 3.2 2 1 1 3 3 3 0 Virulence factor TruD PF01142.18 EKX39518.1 - 1.7e-47 162.2 0.0 1.5e-44 152.5 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Fibrillin_U_N PF18193.1 EKX39519.1 - 0.12 12.5 0.3 28 4.9 0.1 2.8 2 0 0 2 2 2 0 Fibrillin 1 unique N-terminal domain adh_short PF00106.25 EKX39521.1 - 1.6e-32 112.6 0.0 2.1e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EKX39521.1 - 3.5e-20 72.6 0.0 4.6e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX39521.1 - 1.2e-07 31.8 0.0 1.9e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EKX39521.1 - 0.013 15.0 0.0 0.11 12.0 0.0 2.1 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EKX39521.1 - 0.019 14.4 0.0 0.39 10.0 0.0 2.2 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 EKX39521.1 - 0.036 13.2 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Wax2_C PF12076.8 EKX39521.1 - 0.087 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 WAX2 C-terminal domain Ank_2 PF12796.7 EKX39522.1 - 7e-21 74.6 2.6 6.1e-14 52.4 0.6 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX39522.1 - 1.5e-14 53.8 4.2 1.4e-07 31.7 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX39522.1 - 3.9e-13 49.6 0.2 8.2e-08 32.7 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX39522.1 - 3.1e-12 45.5 0.2 0.00016 21.8 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EKX39522.1 - 1.7e-08 34.6 3.9 0.0045 17.4 0.2 3.8 4 0 0 4 4 4 2 Ankyrin repeat V_ATPase_I PF01496.19 EKX39522.1 - 0.14 10.0 4.8 0.29 9.0 4.8 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Occludin_ELL PF07303.13 EKX39522.1 - 0.34 11.7 2.1 0.86 10.4 2.1 1.7 1 0 0 1 1 1 0 Occludin homology domain TMPIT PF07851.13 EKX39522.1 - 3.7 6.7 4.7 6.1 6.0 4.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein AAA PF00004.29 EKX39523.1 - 4.4e-15 56.3 0.0 8.8e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EKX39523.1 - 1.2e-12 47.9 0.0 2.1e-10 40.6 0.0 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 EKX39523.1 - 4.7e-12 46.2 0.0 3e-11 43.6 0.0 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_16 PF13191.6 EKX39523.1 - 1.8e-05 25.2 0.0 0.00021 21.7 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 EKX39523.1 - 2.2e-05 24.4 0.0 0.00012 21.9 0.0 2.0 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.15 EKX39523.1 - 0.00012 22.1 0.0 0.00021 21.3 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 EKX39523.1 - 0.00034 20.4 0.0 0.00078 19.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EKX39523.1 - 0.00061 20.1 0.1 0.043 14.1 0.0 2.5 2 1 1 3 3 2 1 AAA domain AAA_assoc_2 PF16193.5 EKX39523.1 - 0.0018 18.6 0.0 0.0041 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_30 PF13604.6 EKX39523.1 - 0.0018 18.0 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain ADK PF00406.22 EKX39523.1 - 0.0034 17.5 0.0 0.028 14.5 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase Mg_chelatase PF01078.21 EKX39523.1 - 0.0058 16.0 0.2 0.068 12.5 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EKX39523.1 - 0.0077 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EKX39523.1 - 0.011 15.0 0.0 0.032 13.5 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 EKX39523.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 EKX39523.1 - 0.019 14.1 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 EKX39523.1 - 0.02 14.6 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 EKX39523.1 - 0.021 14.6 0.0 0.1 12.3 0.0 2.0 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_19 PF13245.6 EKX39523.1 - 0.028 14.8 0.0 0.12 12.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EKX39523.1 - 0.032 14.2 0.1 0.17 11.9 0.0 2.4 2 2 1 3 3 2 0 AAA domain (dynein-related subfamily) ResIII PF04851.15 EKX39523.1 - 0.038 14.0 0.0 0.12 12.4 0.0 1.7 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 EKX39523.1 - 0.039 14.4 0.0 0.1 13.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 EKX39523.1 - 0.047 13.5 0.0 0.18 11.7 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EKX39523.1 - 0.057 13.7 0.0 0.083 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EKX39523.1 - 0.13 12.8 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain SHMT PF00464.19 EKX39524.1 - 5e-200 664.2 0.0 5.7e-200 664.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 EKX39524.1 - 0.022 14.0 0.0 0.063 12.5 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase Ubie_methyltran PF01209.18 EKX39525.1 - 5.3e-80 268.1 0.0 6e-80 267.9 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EKX39525.1 - 9.3e-18 64.7 0.0 7.3e-17 61.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX39525.1 - 7e-17 61.9 0.0 1.4e-16 60.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX39525.1 - 1.1e-10 41.5 0.0 1.8e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX39525.1 - 1.9e-08 35.0 0.0 3.1e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX39525.1 - 3e-07 30.4 0.0 4.1e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EKX39525.1 - 5.5e-05 23.1 0.0 0.018 14.9 0.0 2.5 3 0 0 3 3 3 2 Hypothetical methyltransferase Beta_elim_lyase PF01212.21 EKX39525.1 - 0.14 11.4 0.2 0.56 9.4 0.0 1.9 2 0 0 2 2 2 0 Beta-eliminating lyase UPF0020 PF01170.18 EKX39525.1 - 0.16 11.6 0.0 0.39 10.4 0.0 1.6 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 DUF4746 PF15928.5 EKX39525.1 - 0.23 10.9 0.0 0.32 10.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TTL PF03133.15 EKX39526.1 - 8.2e-78 261.5 0.5 9.9e-78 261.2 0.5 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EKX39526.1 - 3.9e-06 26.3 0.0 0.0022 17.3 0.0 3.1 3 0 0 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EKX39526.1 - 9e-06 25.1 0.0 0.0025 17.1 0.1 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EKX39526.1 - 0.012 15.6 0.0 0.62 10.1 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain WW PF00397.26 EKX39527.1 - 1.7e-07 31.2 1.6 2.5e-07 30.7 1.6 1.2 1 0 0 1 1 1 1 WW domain Ion_trans PF00520.31 EKX39528.1 - 8.7e-100 333.0 58.0 7.5e-36 123.6 8.3 6.0 5 1 0 5 5 5 5 Ion transport protein HEAT_2 PF13646.6 EKX39528.1 - 1.8e-16 60.3 4.1 8.2e-10 39.0 0.1 4.1 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 EKX39528.1 - 4.8e-12 45.1 7.4 0.0062 16.7 0.1 5.8 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 EKX39528.1 - 1.2e-05 25.7 0.1 0.045 14.3 0.0 2.9 2 0 0 2 2 2 2 HEAT-like repeat Cnd1 PF12717.7 EKX39528.1 - 3.7e-05 23.8 0.2 0.00016 21.8 0.0 2.2 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 EKX39528.1 - 0.019 15.2 0.0 0.43 10.8 0.0 2.6 1 1 1 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 NIF PF03031.18 EKX39528.1 - 0.14 11.9 0.1 0.35 10.6 0.1 1.6 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase Cohesin_HEAT PF12765.7 EKX39528.1 - 0.18 12.1 8.5 0.84 10.0 1.1 3.9 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion TMEM135_C_rich PF15982.5 EKX39528.1 - 3.5 8.2 8.0 3.2 8.4 0.5 3.3 3 0 0 3 3 3 0 N-terminal cysteine-rich region of Transmembrane protein 135 GIT1_C PF12205.8 EKX39529.1 - 0.0062 16.6 0.3 0.019 15.0 0.3 1.8 1 0 0 1 1 1 1 G protein-coupled receptor kinase-interacting protein 1 C term Methyltransf_14 PF08484.11 EKX39529.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain REJ PF02010.15 EKX39530.1 - 6.7e-54 183.4 1.8 1.5e-53 182.3 1.8 1.5 1 0 0 1 1 1 1 REJ domain TIG PF01833.24 EKX39530.1 - 0.043 13.9 20.0 1.5 8.9 0.4 5.6 5 0 0 5 5 5 0 IPT/TIG domain TFIIA PF03153.13 EKX39530.1 - 0.51 10.3 50.0 1.1 9.2 50.0 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ABC_tran_CTD PF16326.5 EKX39530.1 - 0.52 10.6 6.1 2.2 8.6 6.1 2.1 1 0 0 1 1 1 0 ABC transporter C-terminal domain Ammonium_transp PF00909.21 EKX39531.1 - 2.2e-115 385.6 30.9 2.8e-115 385.2 30.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DER1 PF04511.15 EKX39532.1 - 9.3e-51 172.5 10.7 1.2e-50 172.2 10.7 1.1 1 0 0 1 1 1 1 Der1-like family Myosin_head PF00063.21 EKX39533.1 - 1e-224 747.7 7.2 1.6e-224 747.1 7.2 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 EKX39533.1 - 0.00012 21.5 0.4 0.00036 20.1 0.4 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif AAA_22 PF13401.6 EKX39533.1 - 0.0013 19.1 0.2 0.082 13.2 0.0 3.2 2 0 0 2 2 2 1 AAA domain PKcGMP_CC PF16808.5 EKX39533.1 - 0.0023 17.7 1.6 0.0023 17.7 1.6 2.9 3 0 0 3 3 3 1 Coiled-coil N-terminus of cGMP-dependent protein kinase RsgA_GTPase PF03193.16 EKX39533.1 - 0.0064 16.4 0.1 0.04 13.8 0.0 2.4 3 0 0 3 3 3 1 RsgA GTPase DUF5101 PF17031.5 EKX39533.1 - 0.083 13.0 3.1 2.9 8.0 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF5101) AAA_16 PF13191.6 EKX39533.1 - 0.14 12.5 2.0 0.35 11.2 0.0 2.8 4 0 0 4 4 3 0 AAA ATPase domain SH3_19 PF18597.1 EKX39533.1 - 0.18 11.7 0.1 0.52 10.2 0.1 1.7 1 0 0 1 1 1 0 Myosin X N-terminal SH3 domain HALZ PF02183.18 EKX39533.1 - 0.25 11.6 3.0 3.4 8.0 0.1 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper AAA_19 PF13245.6 EKX39533.1 - 0.25 11.7 2.5 1.2 9.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain Atrophin-1 PF03154.15 EKX39533.1 - 0.29 9.4 7.4 0.61 8.3 7.4 1.4 1 0 0 1 1 1 0 Atrophin-1 family Chloroa_b-bind PF00504.21 EKX39534.1 - 2.9e-42 144.9 0.0 4.5e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Ribosomal_S15 PF00312.22 EKX39535.1 - 3.4e-32 110.5 3.1 5.5e-32 109.8 3.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 Peptidase_S8 PF00082.22 EKX39536.1 - 1.9e-39 135.7 0.6 2.5e-39 135.4 0.6 1.1 1 0 0 1 1 1 1 Subtilase family DUF4215 PF13948.6 EKX39537.1 - 5.3e-10 39.6 24.5 1.7e-06 28.4 2.7 4.2 4 0 0 4 4 4 2 Domain of unknown function (DUF4215) cobW PF02492.19 EKX39538.1 - 2.2e-41 141.4 0.1 3e-41 141.0 0.1 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 EKX39538.1 - 0.00045 20.1 0.0 0.00065 19.6 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 EKX39538.1 - 0.0083 16.1 0.1 0.015 15.3 0.1 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE MeaB PF03308.16 EKX39538.1 - 0.012 14.6 0.1 0.018 14.1 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 EKX39538.1 - 0.018 14.8 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 EKX39538.1 - 0.021 15.4 0.1 0.12 12.9 0.2 2.3 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EKX39538.1 - 0.036 13.8 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EKX39538.1 - 0.065 13.6 0.2 0.14 12.5 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EKX39538.1 - 0.066 13.7 0.1 0.14 12.6 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 EKX39538.1 - 0.16 12.2 0.3 0.65 10.3 0.2 1.9 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 EKX39540.1 - 0.037 14.3 0.1 0.65 10.3 0.0 3.2 2 1 0 2 2 2 0 AAA domain DPM3 PF08285.11 EKX39540.1 - 3.5 7.9 12.8 41 4.5 0.6 4.4 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF4398 PF14346.6 EKX39540.1 - 9.2 7.0 79.3 18 6.1 21.8 5.1 1 1 4 5 5 5 0 Domain of unknown function (DUF4398) DNA_pol3_delta PF06144.13 EKX39542.1 - 0.043 13.6 0.1 0.062 13.1 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit PEX11 PF05648.14 EKX39542.1 - 0.075 12.5 2.2 0.055 12.9 0.7 1.5 1 1 1 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) Mito_carr PF00153.27 EKX39543.1 - 1.7e-26 92.0 0.1 5.1e-20 71.2 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF1676 PF07898.13 EKX39544.1 - 1.3 9.0 10.9 0.34 10.9 7.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Metallophos PF00149.28 EKX39545.1 - 7.4e-32 111.5 3.2 9.5e-32 111.1 3.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EKX39545.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Glypican PF01153.19 EKX39546.1 - 0.085 11.7 0.3 0.12 11.2 0.3 1.1 1 0 0 1 1 1 0 Glypican ABC_membrane PF00664.23 EKX39547.1 - 2.4e-38 132.4 7.4 2.4e-38 132.4 7.4 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 EKX39547.1 - 5.3e-17 62.6 0.0 1e-16 61.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 EKX39547.1 - 0.0022 17.3 0.2 0.0062 15.8 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin MTABC_N PF16185.5 EKX39547.1 - 0.0026 17.3 1.3 0.0026 17.3 1.3 3.2 2 1 1 3 3 3 1 Mitochondrial ABC-transporter N-terminal five TM region EMC3_TMCO1 PF01956.16 EKX39547.1 - 0.0063 16.3 0.4 0.0063 16.3 0.4 1.8 2 0 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like AAA_16 PF13191.6 EKX39547.1 - 0.0097 16.3 0.4 0.033 14.6 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 EKX39547.1 - 0.018 14.8 0.9 0.048 13.4 0.9 1.7 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 EKX39547.1 - 0.13 11.6 0.3 15 5.0 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain LRR_8 PF13855.6 EKX39550.1 - 1.2e-22 79.4 17.5 4e-08 32.9 3.0 4.1 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EKX39550.1 - 6.8e-18 64.5 18.8 4.8e-05 23.6 0.1 4.3 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX39550.1 - 5.6e-07 29.6 4.3 1.5e-05 25.0 0.6 2.1 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 EKX39550.1 - 1.9e-05 24.4 23.0 0.098 12.8 0.1 7.0 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 EKX39550.1 - 6.4e-05 23.0 20.1 6.8 7.7 4.4 6.9 4 3 0 4 4 4 3 Leucine Rich Repeat MORN PF02493.20 EKX39551.1 - 2.5e-46 152.8 70.7 1.1e-06 28.2 1.6 10.0 10 0 0 10 10 10 9 MORN repeat BsuPI PF12690.7 EKX39551.1 - 0.1 12.6 4.4 8 6.6 0.0 3.6 2 2 2 4 4 4 0 Intracellular proteinase inhibitor UPF0020 PF01170.18 EKX39552.1 - 5.1e-10 39.4 0.2 4e-08 33.2 0.2 2.4 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 EKX39552.1 - 1.4e-07 31.5 0.0 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 DNA methylase Methyltransf_25 PF13649.6 EKX39552.1 - 0.00047 20.8 0.0 0.001 19.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX39552.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EKX39552.1 - 0.018 15.7 0.0 0.036 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 EKX39552.1 - 0.035 13.8 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 CMAS PF02353.20 EKX39552.1 - 0.14 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase AviRa PF11599.8 EKX39552.1 - 0.15 11.5 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 RRNA methyltransferase AviRa GFA PF04828.14 EKX39553.1 - 1.2e-08 35.2 0.8 1.2e-08 35.2 0.8 1.7 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Casc1_N PF15927.5 EKX39555.1 - 4.9e-37 127.6 19.4 4.9e-37 127.6 19.4 2.9 2 2 0 2 2 2 1 Cancer susceptibility candidate 1 N-terminus RNA_polI_A34 PF08208.11 EKX39555.1 - 0.0001 22.5 9.8 0.0001 22.5 9.8 2.4 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 CobT PF06213.12 EKX39555.1 - 0.0069 15.8 20.3 0.0069 15.8 20.3 2.0 2 0 0 2 2 2 1 Cobalamin biosynthesis protein CobT Zip PF02535.22 EKX39555.1 - 9.9 5.3 9.4 16 4.6 9.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3326 PF11805.8 EKX39556.1 - 7.3e-113 376.8 2.4 5.2e-78 262.3 1.2 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3326) LRR_6 PF13516.6 EKX39557.1 - 1.9e-08 33.7 0.3 0.58 10.4 0.0 5.1 4 0 0 4 4 4 3 Leucine Rich repeat TrkH PF02386.16 EKX39558.1 - 9.6e-56 189.2 16.0 9.1e-53 179.4 8.8 2.1 2 0 0 2 2 2 2 Cation transport protein HTH_30 PF13556.6 EKX39558.1 - 0.19 11.5 0.8 0.48 10.3 0.8 1.7 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain RWP-RK PF02042.15 EKX39559.1 - 3.2e-08 33.4 0.1 6.2e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain NOA36 PF06524.12 EKX39559.1 - 0.0021 17.5 5.6 0.0024 17.2 5.6 1.1 1 0 0 1 1 1 1 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 EKX39559.1 - 0.0031 17.8 3.2 0.0037 17.6 3.2 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 PBP1_TM PF14812.6 EKX39559.1 - 0.0066 16.8 5.6 0.012 16.0 5.6 1.6 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 EKX39559.1 - 0.0091 14.2 4.8 0.0084 14.3 4.8 1.0 1 0 0 1 1 1 1 DNA polymerase phi FYDLN_acid PF09538.10 EKX39559.1 - 0.014 16.0 7.2 0.019 15.6 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Nop14 PF04147.12 EKX39559.1 - 0.14 10.4 5.6 0.14 10.3 5.6 1.0 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.10 EKX39559.1 - 0.28 11.6 13.1 0.46 10.9 13.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 EKX39559.1 - 0.38 10.4 6.5 0.57 9.8 6.5 1.3 1 0 0 1 1 1 0 FAM176 family Sporozoite_P67 PF05642.11 EKX39559.1 - 0.4 8.7 3.6 0.48 8.5 3.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ANAPC15 PF15243.6 EKX39559.1 - 0.95 9.9 12.2 1.6 9.2 12.2 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 RXT2_N PF08595.11 EKX39559.1 - 1.1 9.3 7.8 1.5 8.8 7.8 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.9 EKX39559.1 - 1.6 7.8 14.7 2 7.4 14.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 EKX39559.1 - 2.7 6.2 9.6 3.1 6.0 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 EKX39559.1 - 3.2 7.3 9.8 4.1 6.9 9.8 1.1 1 0 0 1 1 1 0 PPP4R2 SspB PF04386.13 EKX39559.1 - 4 7.3 6.4 5.9 6.7 6.4 1.2 1 0 0 1 1 1 0 Stringent starvation protein B RWP-RK PF02042.15 EKX39560.1 - 5.4e-10 39.1 0.0 1.4e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 RWP-RK domain HSF_DNA-bind PF00447.17 EKX39562.1 - 9.8e-18 64.6 0.1 1.1e-17 64.4 0.1 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding RRM_1 PF00076.22 EKX39564.1 - 2e-15 56.3 0.2 1.2e-11 44.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) La PF05383.17 EKX39564.1 - 1.3e-13 50.7 0.0 3e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 La domain RRM_3 PF08777.11 EKX39564.1 - 1.5e-07 31.4 3.9 0.00015 21.8 2.6 3.0 2 1 0 2 2 2 2 RNA binding motif RRM_7 PF16367.5 EKX39564.1 - 0.028 14.5 0.1 0.12 12.5 0.1 2.0 2 0 0 2 2 2 0 RNA recognition motif Nup35_RRM_2 PF14605.6 EKX39564.1 - 0.17 11.9 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Arm PF00514.23 EKX39565.1 - 4.5e-20 71.0 0.1 0.00012 22.0 0.0 5.3 5 0 0 5 5 5 4 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EKX39565.1 - 1.4e-09 37.8 0.0 0.0011 18.9 0.0 4.2 1 1 4 5 5 5 3 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 EKX39565.1 - 2.2e-08 34.4 8.8 0.053 14.1 1.6 5.9 3 2 3 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 EKX39565.1 - 6.6e-08 32.8 10.8 0.001 19.4 0.3 4.2 1 1 2 3 3 3 3 HEAT repeats HEAT PF02985.22 EKX39565.1 - 9e-08 31.8 6.0 0.46 10.9 0.0 6.5 4 1 3 7 7 7 2 HEAT repeat DUF4630 PF15443.6 EKX39565.1 - 0.0018 18.5 20.1 1.7 8.8 0.9 4.9 2 1 3 5 5 5 3 Domain of unknown function (DUF4630) ADSL_C PF10397.9 EKX39565.1 - 0.0048 17.4 6.4 0.0061 17.1 0.8 2.5 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus IF-2 PF11987.8 EKX39565.1 - 0.037 14.2 4.1 3.6 7.8 0.1 4.0 2 2 1 4 4 4 0 Translation-initiation factor 2 Ocnus PF05005.15 EKX39565.1 - 0.32 11.1 3.4 17 5.6 0.1 2.8 2 2 0 2 2 2 0 Janus/Ocnus family (Ocnus) Pkinase_Tyr PF07714.17 EKX39566.1 - 3.8e-47 160.7 0.0 4.5e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX39566.1 - 2e-25 89.7 0.0 2.3e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain U-box PF04564.15 EKX39567.1 - 1.8e-18 66.5 0.0 2e-18 66.3 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX39567.1 - 0.001 18.8 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EKX39567.1 - 0.016 15.3 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 RING-type zinc-finger zf-NOSIP PF15906.5 EKX39567.1 - 0.05 13.8 0.0 0.064 13.4 0.0 1.2 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_4 PF15227.6 EKX39567.1 - 0.13 12.4 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF4527 PF15030.6 EKX39567.1 - 0.15 11.5 0.0 0.16 11.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) CENP-B_N PF04218.13 EKX39568.1 - 0.00022 20.8 0.1 0.00048 19.7 0.1 1.5 1 1 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_3 PF01381.22 EKX39568.1 - 0.087 12.9 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix CENP-B_N PF04218.13 EKX39569.1 - 0.0005 19.6 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_3 PF01381.22 EKX39569.1 - 0.21 11.7 0.7 0.39 10.8 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix CENP-B_N PF04218.13 EKX39570.1 - 0.0079 15.8 0.6 0.026 14.1 0.6 1.8 1 1 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_3 PF01381.22 EKX39570.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix RRM_1 PF00076.22 EKX39572.1 - 7.7e-42 141.0 0.0 1.5e-08 34.4 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EKX39572.1 - 3.2e-37 126.9 0.0 7.6e-23 80.5 0.0 4.1 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 EKX39572.1 - 8.9e-15 54.7 0.0 4.8e-11 42.7 0.0 3.9 4 0 0 4 4 4 1 RRM-like domain RRM_occluded PF16842.5 EKX39572.1 - 8e-11 41.6 0.0 0.03 14.2 0.0 4.4 4 1 0 4 4 4 3 Occluded RNA-recognition motif RRM_3 PF08777.11 EKX39572.1 - 0.00058 19.9 0.0 4.4 7.4 0.0 3.7 4 0 0 4 4 4 2 RNA binding motif RL PF17797.1 EKX39572.1 - 0.0013 18.7 0.0 0.86 9.6 0.0 2.7 3 0 0 3 3 3 2 RL domain Limkain-b1 PF11608.8 EKX39572.1 - 0.0015 18.5 0.1 0.61 10.2 0.0 3.4 3 0 0 3 3 3 1 Limkain b1 Nup35_RRM_2 PF14605.6 EKX39572.1 - 0.071 13.1 0.0 4.5 7.4 0.0 2.9 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif GILT PF03227.16 EKX39573.1 - 7.4e-06 26.2 0.0 1.6e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) PLDc_N PF13396.6 EKX39573.1 - 0.013 15.4 0.1 0.026 14.4 0.1 1.5 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal THOC7 PF05615.13 EKX39574.1 - 0.03 14.6 1.2 0.03 14.6 1.2 2.3 3 0 0 3 3 3 0 Tho complex subunit 7 DUF2052 PF09747.9 EKX39574.1 - 0.12 12.5 2.7 4.6 7.3 0.0 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) FH2 PF02181.23 EKX39575.1 - 6.7e-11 41.9 1.1 8e-11 41.7 1.1 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain Clavanin PF05452.11 EKX39575.1 - 0.099 12.9 0.1 0.16 12.2 0.1 1.2 1 0 0 1 1 1 0 Clavanin Phage_TAC_14 PF16462.5 EKX39576.1 - 0.0058 16.9 4.7 30 4.9 0.1 4.7 1 1 1 2 2 2 2 Phage tail assembly chaperone protein, TAC UCH PF00443.29 EKX39579.1 - 2.1e-50 171.6 0.1 2.7e-50 171.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EKX39579.1 - 8.5e-22 78.2 0.2 4e-18 66.1 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Desulfoferrod_N PF06397.12 EKX39579.1 - 0.034 13.8 4.0 2.3 7.9 0.3 2.4 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain MORN PF02493.20 EKX39580.1 - 1.5e-26 90.7 34.4 4.1e-07 29.5 0.3 6.1 7 0 0 7 7 7 5 MORN repeat DUF3048_C PF17479.2 EKX39580.1 - 0.02 15.3 4.0 0.055 13.9 0.1 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3048) C-terminal domain TEX19 PF15553.6 EKX39581.1 - 0.028 14.4 0.2 0.05 13.6 0.2 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 Methyltransf_25 PF13649.6 EKX39582.1 - 5.4e-17 62.3 0.0 1e-16 61.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX39582.1 - 6.2e-15 55.3 0.0 1.1e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX39582.1 - 3.3e-12 47.0 0.0 5.9e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX39582.1 - 1.3e-09 38.6 0.0 2.3e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX39582.1 - 2.1e-09 37.1 0.1 4.2e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EKX39582.1 - 6.5e-07 29.3 0.0 1.3e-06 28.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EKX39582.1 - 6.5e-05 22.5 0.0 0.00014 21.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_15 PF09445.10 EKX39582.1 - 0.00031 20.3 0.0 0.00049 19.7 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.17 EKX39582.1 - 0.00057 19.4 0.0 0.0023 17.4 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.19 EKX39582.1 - 0.014 15.2 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 EKX39582.1 - 0.018 15.0 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 EKX39582.1 - 0.04 13.3 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltr_RsmB-F PF01189.17 EKX39582.1 - 0.057 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F PrmA PF06325.13 EKX39582.1 - 0.082 12.3 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.6 EKX39582.1 - 0.09 13.8 0.0 0.25 12.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 EKX39582.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 EKX39582.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Glu_cyclase_2 PF05096.12 EKX39585.1 - 2.3e-82 276.2 1.4 3.2e-80 269.2 1.4 2.0 1 1 0 1 1 1 1 Glutamine cyclotransferase MMS1_N PF10433.9 EKX39586.1 - 5e-22 78.2 0.0 2.3e-20 72.7 0.0 3.0 2 1 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Myb_DNA-binding PF00249.31 EKX39587.1 - 2.5e-06 27.6 0.0 0.03 14.5 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain TEA PF01285.18 EKX39587.1 - 0.0042 17.1 0.0 0.0071 16.4 0.0 1.3 1 0 0 1 1 1 1 TEA/ATTS domain Myb_DNA-binding PF00249.31 EKX39588.1 - 3.1e-07 30.5 0.1 2.5e-06 27.6 0.1 2.2 1 1 0 1 1 1 1 Myb-like DNA-binding domain TEA PF01285.18 EKX39588.1 - 0.0027 17.7 0.0 0.0047 17.0 0.0 1.4 1 0 0 1 1 1 1 TEA/ATTS domain Myb_DNA-binding PF00249.31 EKX39589.1 - 0.18 12.0 0.0 0.53 10.5 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EKX39590.1 - 1.4e-05 25.2 0.8 0.00036 20.7 0.2 2.7 2 1 0 2 2 2 1 Myb-like DNA-binding domain TEA PF01285.18 EKX39590.1 - 0.0048 17.0 0.0 0.039 14.0 0.0 2.3 2 0 0 2 2 2 1 TEA/ATTS domain DUF5401 PF17380.2 EKX39590.1 - 0.46 8.5 2.0 0.59 8.1 2.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) KAR9 PF08580.10 EKX39590.1 - 3.4 6.1 14.8 4.3 5.8 14.8 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Macoilin PF09726.9 EKX39590.1 - 8.7 4.8 8.9 10 4.5 8.9 1.3 1 0 0 1 1 1 0 Macoilin family DUF3565 PF12088.8 EKX39591.1 - 0.24 11.4 2.8 2.8 7.9 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3565) Rotamase_3 PF13616.6 EKX39592.1 - 9e-08 32.7 0.1 2.5e-07 31.3 0.1 1.7 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 EKX39592.1 - 2.4e-05 25.2 0.1 4.4e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Radical_SAM PF04055.21 EKX39593.1 - 1.1e-31 110.4 1.0 1.7e-31 109.8 1.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 EKX39593.1 - 4.5e-27 94.0 0.3 1e-26 92.8 0.3 1.7 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 EKX39593.1 - 1.4e-10 41.0 0.6 3.9e-10 39.6 0.6 1.8 1 0 0 1 1 1 1 TRAM domain Fer4_12 PF13353.6 EKX39593.1 - 0.032 14.5 0.0 0.29 11.4 0.0 2.3 2 0 0 2 2 2 0 4Fe-4S single cluster domain TRAM_2 PF18693.1 EKX39593.1 - 0.041 14.0 0.8 0.19 11.9 0.8 2.0 1 1 0 1 1 1 0 TRAM domain MTS_N PF08468.11 EKX39594.1 - 3.2 7.8 8.4 0.22 11.6 1.0 2.7 2 1 1 3 3 3 0 Methyltransferase small domain N-terminal DUF3456 PF11938.8 EKX39595.1 - 0.045 14.3 8.7 0.84 10.1 0.5 2.9 1 1 2 3 3 3 0 TLR4 regulator and MIR-interacting MSAP DUF1289 PF06945.13 EKX39595.1 - 0.3 10.9 2.5 0.48 10.3 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) HATPase_c_3 PF13589.6 EKX39596.1 - 1.6e-06 28.0 0.1 3.6e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 EKX39596.1 - 2.1e-05 24.2 0.2 0.0031 17.2 0.0 3.1 3 0 0 3 3 3 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 EKX39596.1 - 0.0038 17.7 0.0 0.007 16.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Histone PF00125.24 EKX39597.1 - 2.5e-20 73.2 0.0 3.6e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EKX39597.1 - 7.9e-13 47.9 0.9 1.5e-12 47.0 0.9 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EKX39597.1 - 0.01 16.1 0.0 0.015 15.6 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Zn_clus PF00172.18 EKX39600.1 - 4.3e-09 36.4 10.4 6.1e-09 35.9 10.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Toxin_22 PF08092.11 EKX39600.1 - 0.081 13.0 2.0 0.15 12.2 2.0 1.4 1 0 0 1 1 1 0 Magi peptide toxin family DUF4078 PF13300.6 EKX39601.1 - 0.23 11.8 1.6 0.3 11.4 1.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4078) Zn_clus PF00172.18 EKX39602.1 - 2.1e-08 34.1 10.8 3e-08 33.6 10.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.22 EKX39604.1 - 1.3e-18 66.5 0.1 7.4e-09 35.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1491 PF07372.12 EKX39604.1 - 0.13 12.6 0.0 0.35 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1491) Tmemb_185A PF10269.9 EKX39605.1 - 9.8e-11 41.8 25.9 4.3e-07 29.9 6.9 2.4 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein zf-C3HC4_3 PF13920.6 EKX39605.1 - 1.2e-09 37.9 22.9 1.2e-09 37.9 22.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX39605.1 - 0.0042 17.4 19.3 0.0042 17.4 19.3 2.0 2 0 0 2 2 2 1 Ring finger domain DUF1331 PF07048.11 EKX39605.1 - 0.034 13.8 0.4 0.078 12.7 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) Prok-RING_4 PF14447.6 EKX39605.1 - 8.4 6.3 22.1 21 5.1 22.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Peptidase_M17 PF00883.21 EKX39606.1 - 1.3e-100 336.7 0.1 1.6e-100 336.4 0.1 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain MoCF_biosynth PF00994.24 EKX39607.1 - 5.1e-22 78.1 0.0 5.8e-22 77.9 0.0 1.0 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_N PF03453.17 EKX39608.1 - 6.9e-23 81.1 1.4 8.7e-23 80.8 1.4 1.2 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 EKX39608.1 - 1.1e-08 34.8 0.2 2.3e-08 33.8 0.0 1.6 2 0 0 2 2 2 1 Probable molybdopterin binding domain p450 PF00067.22 EKX39609.1 - 3.2e-72 243.8 0.0 4.2e-72 243.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RWP-RK PF02042.15 EKX39610.1 - 8.1e-23 80.2 0.1 1.1e-22 79.7 0.1 1.2 1 0 0 1 1 1 1 RWP-RK domain HTH_6 PF01418.17 EKX39610.1 - 0.18 11.8 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family RRM_1 PF00076.22 EKX39611.1 - 4.2e-38 129.0 0.0 1.1e-19 69.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EKX39611.1 - 7.5e-07 29.1 0.0 0.035 14.2 0.0 2.3 2 0 0 2 2 2 2 Limkain b1 RRM_5 PF13893.6 EKX39611.1 - 0.00047 19.7 0.0 0.32 10.6 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-grasp_2 PF08442.10 EKX39611.1 - 0.0011 18.6 0.0 1.1 8.8 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp domain RRM_occluded PF16842.5 EKX39611.1 - 0.0012 18.7 0.0 0.73 9.7 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF3343 PF11823.8 EKX39611.1 - 0.017 14.6 0.1 0.4 10.2 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3343) SPOR PF05036.13 EKX39611.1 - 0.02 15.3 0.0 7.7 7.0 0.0 3.1 2 2 0 2 2 2 0 Sporulation related domain RRM_3 PF08777.11 EKX39611.1 - 0.02 14.9 0.0 3.2 7.8 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif DUF2778 PF10908.8 EKX39611.1 - 0.057 13.7 0.0 8.5 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2778) YkuD_2 PF13645.6 EKX39611.1 - 0.094 12.2 0.0 9.9 5.6 0.0 2.1 2 0 0 2 2 2 0 L,D-transpeptidase catalytic domain SPC12 PF06645.13 EKX39612.1 - 0.0031 17.5 0.3 0.0045 17.1 0.3 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) COX4 PF02936.14 EKX39612.1 - 0.0085 16.1 0.2 0.014 15.4 0.2 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV EAV_GS PF01309.18 EKX39613.1 - 0.047 13.3 0.1 0.059 13.0 0.1 1.1 1 0 0 1 1 1 0 Equine arteritis virus small envelope glycoprotein DUF3989 PF13150.6 EKX39613.1 - 0.17 11.6 0.1 0.22 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) Amnionless PF14828.6 EKX39613.1 - 0.19 10.6 0.0 0.2 10.5 0.0 1.0 1 0 0 1 1 1 0 Amnionless Proteasom_Rpn13 PF04683.13 EKX39614.1 - 8.1e-11 42.3 0.0 2.3e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor CHB_HEX_C_1 PF13290.6 EKX39614.1 - 0.00027 20.9 0.1 0.006 16.6 0.1 2.3 1 1 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 EKX39614.1 - 0.00076 19.6 0.0 0.019 15.1 0.0 2.5 1 1 0 1 1 1 1 Fn3 associated Ank_2 PF12796.7 EKX39616.1 - 4.6e-21 75.2 0.0 8.5e-14 51.9 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX39616.1 - 1.7e-14 54.0 0.2 6.1e-11 42.6 0.0 2.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX39616.1 - 1.4e-12 47.5 0.1 4e-09 36.6 0.0 2.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX39616.1 - 3.8e-10 39.8 0.0 5.1e-05 23.5 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EKX39616.1 - 7e-10 38.3 0.0 0.00016 21.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ureide_permease PF07168.11 EKX39617.1 - 0.042 12.6 0.1 0.062 12.1 0.1 1.3 1 0 0 1 1 1 0 Ureide permease SafA PF17073.5 EKX39617.1 - 0.15 12.1 0.1 0.43 10.6 0.0 1.8 2 0 0 2 2 2 0 Two-component-system connector protein DUF4551 PF15087.6 EKX39617.1 - 0.16 10.7 6.0 0.21 10.4 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) FtsX PF02687.21 EKX39617.1 - 0.46 11.0 3.8 0.54 10.8 0.5 2.3 2 1 0 2 2 2 0 FtsX-like permease family TFIIA PF03153.13 EKX39617.1 - 3.7 7.4 8.5 4.5 7.2 8.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit THOC2_N PF16134.5 EKX39617.1 - 5.2 5.6 5.7 7 5.1 5.7 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus WW PF00397.26 EKX39621.1 - 7.3e-09 35.6 3.0 2.4e-08 33.9 3.0 1.9 1 0 0 1 1 1 1 WW domain DUF1031 PF06275.11 EKX39621.1 - 0.0096 16.2 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1031) Acyl-ACP_TE PF01643.17 EKX39621.1 - 0.06 12.6 0.1 0.098 11.9 0.1 1.3 1 0 0 1 1 1 0 Acyl-ACP thioesterase HlyIII PF03006.20 EKX39622.1 - 2.5e-25 89.5 13.7 1.3e-14 54.4 5.0 2.1 1 1 1 2 2 2 2 Haemolysin-III related DUF5472 PF17566.2 EKX39622.1 - 0.25 11.3 2.2 0.31 11.0 0.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5472) Abhydrolase_1 PF00561.20 EKX39623.1 - 3.2e-13 49.9 0.1 6.7e-11 42.3 0.0 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold WW PF00397.26 EKX39623.1 - 6.3e-11 42.2 0.7 1.2e-10 41.3 0.3 1.8 2 0 0 2 2 2 1 WW domain Hydrolase_4 PF12146.8 EKX39623.1 - 2.7e-08 33.4 0.0 1.3e-07 31.1 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EKX39623.1 - 9.2e-06 26.4 0.1 1.7e-05 25.6 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 EKX39623.1 - 0.064 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase Casc1_N PF15927.5 EKX39623.1 - 0.2 11.3 10.4 0.38 10.4 10.4 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Nop14 PF04147.12 EKX39623.1 - 0.28 9.4 2.5 0.37 9.0 2.5 1.1 1 0 0 1 1 1 0 Nop14-like family C2 PF00168.30 EKX39625.1 - 3.5e-15 56.2 0.0 7.3e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain VPS28 PF03997.12 EKX39625.1 - 0.034 13.8 0.2 0.058 13.1 0.2 1.3 1 0 0 1 1 1 0 VPS28 protein CAP_N PF01213.19 EKX39626.1 - 2e-59 201.7 1.1 2e-32 112.9 0.2 2.0 1 1 1 2 2 2 2 Adenylate cyclase associated (CAP) N terminal GSH_synth_ATP PF03917.17 EKX39626.1 - 0.084 11.6 0.1 0.14 10.9 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic glutathione synthase, ATP binding domain Acetyltransf_1 PF00583.25 EKX39627.1 - 3.4e-17 62.7 0.0 5.6e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EKX39627.1 - 1.8e-12 47.3 0.0 2.3e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EKX39627.1 - 2e-08 34.5 0.1 3.9e-08 33.6 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EKX39627.1 - 1.2e-07 31.6 0.0 1.9e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EKX39627.1 - 0.012 16.3 0.0 0.016 15.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EKX39627.1 - 0.024 14.8 0.0 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 EKX39627.1 - 0.026 14.7 0.0 0.042 14.0 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 EKX39627.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_9 PF13527.7 EKX39627.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EKX39627.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PDZ_6 PF17820.1 EKX39628.1 - 9.9e-10 38.1 0.3 1.6e-09 37.5 0.3 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX39628.1 - 0.00015 22.0 0.0 0.00024 21.4 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX39628.1 - 0.00067 20.0 0.1 0.00093 19.5 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX39628.1 - 0.044 13.7 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 Tricorn protease PDZ domain Ammonium_transp PF00909.21 EKX39629.1 - 1.3e-29 103.1 3.1 1.7e-29 102.7 3.1 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family MMS19_N PF14500.6 EKX39630.1 - 4.9e-56 190.2 0.6 6.5e-55 186.5 0.0 3.1 4 0 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 EKX39630.1 - 1.9e-25 89.9 0.1 9.4e-24 84.3 0.1 2.7 1 1 0 1 1 1 1 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.6 EKX39630.1 - 0.46 11.1 2.5 20 5.8 0.2 4.0 3 0 0 3 3 3 0 HEAT-like repeat FabA PF07977.13 EKX39631.1 - 3.3e-31 107.8 0.1 4.6e-31 107.3 0.1 1.2 1 0 0 1 1 1 1 FabA-like domain MaoC_dehydrat_N PF13452.6 EKX39631.1 - 0.055 13.6 0.0 0.097 12.8 0.0 1.4 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase Coq4 PF05019.13 EKX39632.1 - 8.1e-82 273.8 0.0 9.5e-82 273.6 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 IgGFc_binding PF17517.2 EKX39632.1 - 0.013 14.8 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 IgGFc binding protein HSP70 PF00012.20 EKX39634.1 - 7.1 4.7 10.6 0.2 9.8 4.1 1.6 2 0 0 2 2 2 0 Hsp70 protein Pex14_N PF04695.13 EKX39636.1 - 6.2e-22 78.9 3.9 6.2e-22 78.9 3.9 2.4 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Glyco_hydro_1 PF00232.18 EKX39636.1 - 0.0002 19.9 0.0 0.00037 19.0 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 EssA PF10661.9 EKX39636.1 - 0.027 14.3 2.4 0.076 12.9 0.1 2.3 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA HTH_37 PF13744.6 EKX39636.1 - 0.04 13.9 2.5 0.063 13.2 0.5 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain DUF3215 PF11503.8 EKX39636.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3215) DUF4366 PF14283.6 EKX39636.1 - 0.17 11.9 0.1 0.17 11.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) Halogen_Hydrol PF10112.9 EKX39636.1 - 0.68 9.9 6.8 0.67 9.9 1.4 2.7 2 1 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein LMBR1 PF04791.16 EKX39636.1 - 6.7 5.5 10.3 0.27 10.1 4.2 1.8 1 1 1 2 2 2 0 LMBR1-like membrane protein Snapin_Pallidin PF14712.6 EKX39636.1 - 7 7.2 11.7 0.64 10.5 4.4 2.5 2 0 0 2 2 2 0 Snapin/Pallidin Pkinase PF00069.25 EKX39637.1 - 4.4e-75 252.5 0.0 5.1e-75 252.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX39637.1 - 1.9e-43 148.7 0.0 2.3e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX39637.1 - 5.3e-06 26.0 0.0 0.00015 21.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EKX39637.1 - 0.0025 16.8 0.0 0.0047 15.9 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EKX39637.1 - 0.006 16.2 0.0 0.026 14.1 0.0 1.8 1 1 1 2 2 2 1 RIO1 family Seadorna_VP7 PF07387.11 EKX39637.1 - 0.0064 15.6 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 EKX39637.1 - 0.0066 16.4 0.1 0.039 13.9 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX39637.1 - 0.038 13.4 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EKX39637.1 - 0.049 12.4 0.0 0.084 11.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase LRR_6 PF13516.6 EKX39638.1 - 7.3e-12 44.3 22.5 9e-05 22.2 0.3 7.3 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.7 EKX39638.1 - 0.055 13.9 14.7 0.77 10.3 2.0 5.2 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) Pkinase_Tyr PF07714.17 EKX39639.1 - 2.7e-42 144.8 0.0 3e-42 144.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX39639.1 - 2.6e-16 59.8 0.0 3.1e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain U-box PF04564.15 EKX39640.1 - 3.6e-17 62.3 0.0 4.2e-17 62.1 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 EKX39640.1 - 0.0047 17.0 0.0 0.0066 16.6 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 EKX39640.1 - 0.045 13.6 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EKX39640.1 - 0.081 13.0 0.0 0.12 12.5 0.0 1.5 1 1 0 1 1 1 0 RING-type zinc-finger CK_II_beta PF01214.18 EKX39641.1 - 0.051 13.4 0.7 0.094 12.5 0.7 1.3 1 0 0 1 1 1 0 Casein kinase II regulatory subunit Peptidase_S24 PF00717.23 EKX39642.1 - 1.8e-13 50.2 0.1 3.7e-13 49.2 0.1 1.6 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EKX39642.1 - 2e-10 40.6 0.0 5.7e-10 39.1 0.0 1.7 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Na_H_Exchanger PF00999.21 EKX39653.1 - 4e-20 71.9 27.4 5.5e-20 71.5 27.4 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family E1-E2_ATPase PF00122.20 EKX39653.1 - 3 7.3 9.4 1.6 8.2 0.3 2.6 3 0 0 3 3 3 0 E1-E2 ATPase TrkA_N PF02254.18 EKX39654.1 - 2.7e-09 37.3 0.2 0.0047 17.2 0.0 3.5 2 1 1 3 3 3 3 TrkA-N domain WDCP PF15390.6 EKX39654.1 - 0.025 13.0 6.3 0.039 12.4 6.3 1.3 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF1664 PF07889.12 EKX39656.1 - 0.002 18.2 8.3 0.0021 18.1 4.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) K-box PF01486.17 EKX39656.1 - 0.013 15.7 13.6 0.12 12.6 7.5 2.6 2 1 0 2 2 2 0 K-box region UPF0242 PF06785.11 EKX39656.1 - 0.031 14.4 10.7 0.047 13.8 10.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 EKX39656.1 - 0.042 11.8 9.3 0.05 11.5 9.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF724 PF05266.14 EKX39656.1 - 0.053 13.3 13.5 0.018 14.9 6.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Prefoldin_2 PF01920.20 EKX39656.1 - 0.13 12.2 13.7 0.17 11.8 3.0 3.2 2 1 1 3 3 3 0 Prefoldin subunit DUF2205 PF10224.9 EKX39656.1 - 0.17 11.9 13.4 0.06 13.4 4.2 2.8 1 1 1 2 2 2 0 Short coiled-coil protein Macoilin PF09726.9 EKX39656.1 - 0.18 10.3 12.7 0.21 10.1 12.7 1.1 1 0 0 1 1 1 0 Macoilin family GTP-bdg_M PF16360.5 EKX39656.1 - 0.2 12.3 9.2 0.26 11.9 2.2 2.4 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region DUF4962 PF16332.5 EKX39656.1 - 0.31 9.5 2.1 0.37 9.2 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) BST2 PF16716.5 EKX39656.1 - 0.4 11.3 16.6 1.9 9.1 8.8 2.5 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 ERM PF00769.19 EKX39656.1 - 0.54 10.0 22.9 0.97 9.2 22.9 1.4 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Spc7 PF08317.11 EKX39656.1 - 0.55 9.0 17.1 0.73 8.7 17.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Prefoldin PF02996.17 EKX39656.1 - 0.59 10.1 10.9 0.42 10.5 0.9 3.0 1 1 2 3 3 3 0 Prefoldin subunit TolA_bind_tri PF16331.5 EKX39656.1 - 0.69 10.0 17.7 0.046 13.8 7.2 2.7 1 1 2 3 3 3 0 TolA binding protein trimerisation APG6_N PF17675.1 EKX39656.1 - 0.69 10.4 20.3 0.19 12.3 11.2 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Syntaxin-6_N PF09177.11 EKX39656.1 - 0.72 10.5 8.3 0.89 10.1 2.2 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal YlqD PF11068.8 EKX39656.1 - 0.87 10.0 16.4 1.2 9.5 7.2 2.1 1 1 1 2 2 2 0 YlqD protein DUF3450 PF11932.8 EKX39656.1 - 0.95 8.7 17.3 2.6 7.3 2.3 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Mis12 PF05859.12 EKX39656.1 - 0.99 9.5 8.9 5.9 7.0 8.9 2.2 1 1 0 1 1 1 0 Mis12 protein FapA PF03961.13 EKX39656.1 - 1 7.9 8.6 2.1 6.9 7.4 1.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A Fez1 PF06818.15 EKX39656.1 - 1.1 9.7 16.8 0.16 12.4 6.8 2.1 1 1 1 2 2 2 0 Fez1 ESM4 PF15952.5 EKX39656.1 - 1.3 9.5 9.6 1.7 9.0 9.6 1.3 1 1 0 1 1 1 0 Enhancer of split M4 family ZapB PF06005.12 EKX39656.1 - 1.3 9.5 19.6 2.1 8.8 5.6 3.1 2 1 1 3 3 3 0 Cell division protein ZapB DUF1690 PF07956.11 EKX39656.1 - 1.3 9.4 15.3 0.32 11.4 9.8 2.0 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) ADIP PF11559.8 EKX39656.1 - 1.7 8.7 19.8 3.5 7.7 8.2 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.6 EKX39656.1 - 1.8 9.0 15.9 16 5.9 15.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DMPK_coil PF08826.10 EKX39656.1 - 2.3 8.4 15.5 0.78 9.9 3.5 3.0 1 1 1 3 3 3 0 DMPK coiled coil domain like Nup54 PF13874.6 EKX39656.1 - 2.5 8.2 17.5 6 7.0 17.4 1.7 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 SOGA PF11365.8 EKX39656.1 - 2.6 9.2 14.5 3.4 8.9 1.8 2.2 1 1 1 2 2 2 0 Protein SOGA ACCA PF03255.14 EKX39656.1 - 3.9 7.3 9.3 4.5 7.1 2.5 2.2 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Spc24 PF08286.11 EKX39656.1 - 5.2 7.4 13.0 18 5.6 5.5 2.9 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 HAUS-augmin3 PF14932.6 EKX39656.1 - 8.7 5.8 16.1 0.91 9.1 9.7 1.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Peptidase_M26_N PF05342.14 EKX39657.1 - 0.56 9.6 2.5 0.38 10.1 1.1 1.4 2 0 0 2 2 2 0 M26 IgA1-specific Metallo-endopeptidase N-terminal region PBP1_TM PF14812.6 EKX39657.1 - 2.3 8.7 6.8 0.54 10.7 3.4 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sel1 PF08238.12 EKX39658.1 - 1.3e-26 92.4 4.7 2.5e-13 50.2 0.2 3.4 3 0 0 3 3 3 2 Sel1 repeat TPR_6 PF13174.6 EKX39658.1 - 7.5e-05 23.1 0.1 0.44 11.3 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX39658.1 - 0.0091 15.8 0.2 6.6 6.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX39658.1 - 0.015 15.0 1.6 20 4.9 0.0 3.3 3 0 0 3 3 3 0 TPR repeat PFO_beta_C PF12367.8 EKX39658.1 - 0.09 12.9 0.4 0.23 11.6 0.4 1.8 1 1 0 1 1 1 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal UVR PF02151.19 EKX39659.1 - 3e-10 39.5 10.8 0.00011 21.8 5.7 2.4 2 0 0 2 2 2 2 UvrB/uvrC motif XRCC1_N PF01834.16 EKX39659.1 - 0.0055 16.7 0.0 0.0099 15.9 0.0 1.4 1 0 0 1 1 1 1 XRCC1 N terminal domain E1-E2_ATPase PF00122.20 EKX39660.1 - 1.5e-32 112.6 0.4 6.3e-32 110.6 0.1 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EKX39660.1 - 7.5e-32 110.5 0.8 7.5e-32 110.5 0.8 2.5 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EKX39660.1 - 9.3e-16 58.7 0.0 4.4e-09 36.9 0.0 2.7 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EKX39660.1 - 4.1e-13 49.2 0.1 1.1e-12 47.8 0.1 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EKX39660.1 - 3.9e-07 29.7 0.0 1.1e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EKX39660.1 - 0.00037 20.3 6.9 0.00041 20.2 0.5 3.0 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF2628 PF10947.8 EKX39660.1 - 0.18 12.2 0.4 46 4.5 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) TIR_2 PF13676.6 EKX39661.1 - 0.035 14.7 0.0 0.077 13.6 0.0 1.6 1 0 0 1 1 1 0 TIR domain Lebercilin PF15619.6 EKX39664.1 - 2 8.1 18.5 0.093 12.4 10.0 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease T3SSipB PF16535.5 EKX39664.1 - 3.5 8.1 12.5 0.093 13.2 1.4 2.7 2 1 1 3 3 3 0 Type III cell invasion protein SipB Uds1 PF15456.6 EKX39664.1 - 4.5 7.5 16.7 93 3.2 14.8 2.8 1 1 1 2 2 2 0 Up-regulated During Septation PRKCSH-like PF12999.7 EKX39665.1 - 5.5e-12 45.8 9.6 5.5e-12 45.8 9.6 7.4 8 0 0 8 8 8 1 Glucosidase II beta subunit-like AMMECR1 PF01871.17 EKX39667.1 - 8.1e-47 158.9 0.0 9.2e-47 158.7 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 GMP_PDE_delta PF05351.11 EKX39668.1 - 6.8e-35 120.4 0.2 1.2e-34 119.6 0.2 1.4 1 1 0 1 1 1 1 GMP-PDE, delta subunit DUF2067 PF09840.9 EKX39669.1 - 0.079 12.5 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) Phage_fiber_2 PF03406.13 EKX39669.1 - 1.4 8.5 5.6 37 4.0 0.7 3.8 3 0 0 3 3 3 0 Phage tail fibre repeat hNIFK_binding PF12196.8 EKX39669.1 - 10 5.7 9.0 15 5.2 0.1 3.5 3 0 0 3 3 3 0 FHA Ki67 binding domain of hNIFK ABC_tran PF00005.27 EKX39671.1 - 7.1e-18 65.4 0.1 1.6e-17 64.3 0.1 1.5 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EKX39671.1 - 8.9e-05 22.9 0.1 0.00012 22.5 0.1 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EKX39671.1 - 0.00027 20.6 0.8 0.00046 19.9 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EKX39671.1 - 0.002 18.2 0.0 0.0031 17.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_5 PF07728.14 EKX39671.1 - 0.0026 17.8 0.1 0.13 12.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) SMC_N PF02463.19 EKX39671.1 - 0.0059 16.1 0.2 0.13 11.6 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EKX39671.1 - 0.022 14.7 0.1 0.079 12.9 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase SbcCD_C PF13558.6 EKX39671.1 - 0.054 13.7 1.7 0.24 11.7 1.7 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 EKX39671.1 - 0.066 13.0 0.1 1.1 9.0 0.0 2.0 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system G-alpha PF00503.20 EKX39671.1 - 0.084 12.0 0.0 0.084 12.0 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA_22 PF13401.6 EKX39671.1 - 0.1 12.9 0.1 0.16 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain dNK PF01712.19 EKX39671.1 - 0.13 12.1 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_25 PF13481.6 EKX39671.1 - 0.21 11.1 1.0 0.31 10.6 1.0 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EKX39672.1 - 7.3e-25 88.1 0.0 1.2e-24 87.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EKX39672.1 - 2.5e-06 27.1 0.0 0.0017 17.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EKX39672.1 - 4.7e-05 23.3 0.1 0.047 13.5 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EKX39672.1 - 0.0064 16.6 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PCSK9_C1 PF18459.1 EKX39672.1 - 0.0067 16.6 0.2 0.02 15.0 0.2 1.7 1 0 0 1 1 1 1 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain AAA_23 PF13476.6 EKX39672.1 - 0.024 15.1 0.0 0.048 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EKX39672.1 - 0.035 14.5 0.2 0.084 13.3 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EKX39672.1 - 0.054 13.4 0.0 0.15 12.0 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 EKX39672.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 EKX39672.1 - 0.13 11.9 0.0 5.2 6.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 EKX39672.1 - 0.16 11.5 0.0 0.51 9.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EKX39672.1 - 0.17 12.1 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 EKX39672.1 - 0.17 12.3 0.0 0.55 10.7 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EKX39672.1 - 0.25 10.5 0.2 0.51 9.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 EKX39672.1 - 0.26 10.8 0.0 0.39 10.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_2 PF07724.14 EKX39675.1 - 7.2e-49 166.2 0.0 8.9e-47 159.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EKX39675.1 - 5.8e-34 116.1 0.2 5.8e-34 116.1 0.2 2.6 2 0 0 2 2 2 1 AAA lid domain AAA PF00004.29 EKX39675.1 - 2.6e-23 82.9 0.2 1.3e-11 45.0 0.0 3.2 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EKX39675.1 - 2.6e-17 62.7 0.2 1.4e-16 60.3 0.0 2.4 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EKX39675.1 - 4.4e-15 55.9 0.2 5.1e-10 39.5 0.0 3.4 3 1 1 4 4 4 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EKX39675.1 - 1e-14 55.3 4.5 1.4e-05 25.5 0.1 4.8 4 1 1 5 5 5 2 AAA ATPase domain AAA_22 PF13401.6 EKX39675.1 - 3e-09 37.3 0.3 0.0037 17.5 0.0 4.4 2 2 1 3 3 3 2 AAA domain IstB_IS21 PF01695.17 EKX39675.1 - 1e-07 31.9 0.0 0.018 14.8 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 EKX39675.1 - 3e-07 30.2 0.0 0.012 15.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region Sigma54_activat PF00158.26 EKX39675.1 - 3.9e-06 26.7 0.2 0.00075 19.2 0.0 2.6 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 EKX39675.1 - 6.6e-06 26.0 0.0 0.015 15.2 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EKX39675.1 - 3.2e-05 24.5 0.0 0.063 13.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EKX39675.1 - 5.1e-05 23.1 1.5 0.72 9.6 0.0 4.4 3 1 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EKX39675.1 - 6.6e-05 22.9 0.0 0.58 10.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.12 EKX39675.1 - 9.9e-05 21.7 0.0 0.0061 15.9 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.22 EKX39675.1 - 0.00014 22.2 0.1 0.39 11.1 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_33 PF13671.6 EKX39675.1 - 0.00025 21.2 0.0 0.073 13.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EKX39675.1 - 0.00037 20.5 0.1 0.13 12.1 0.0 2.8 2 1 0 2 2 2 1 NACHT domain AAA_19 PF13245.6 EKX39675.1 - 0.00096 19.5 0.2 2.2 8.6 0.0 3.4 2 1 1 3 3 3 1 AAA domain DUF815 PF05673.13 EKX39675.1 - 0.0011 18.2 0.2 4.6 6.3 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Roc PF08477.13 EKX39675.1 - 0.0014 18.9 0.0 2.6 8.3 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 EKX39675.1 - 0.0019 18.2 0.0 1.6 8.7 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EKX39675.1 - 0.0023 17.7 0.0 1.2 8.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EKX39675.1 - 0.0028 18.2 0.3 3.1 8.3 0.0 3.3 3 0 0 3 3 3 1 ABC transporter AAA_28 PF13521.6 EKX39675.1 - 0.0041 17.4 0.0 3.2 8.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 EKX39675.1 - 0.0077 16.4 2.0 1.7 8.7 0.0 3.2 3 0 0 3 3 3 1 Helicase HerA, central domain DNA_pol3_delta2 PF13177.6 EKX39675.1 - 0.011 15.6 0.0 1.1 9.1 0.0 2.7 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_30 PF13604.6 EKX39675.1 - 0.012 15.4 0.0 6.2 6.5 0.0 3.0 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 EKX39675.1 - 0.012 15.3 0.0 0.65 9.6 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 EKX39675.1 - 0.017 15.0 0.0 6.3 6.7 0.0 2.8 2 0 0 2 2 2 0 RsgA GTPase Mg_chelatase PF01078.21 EKX39675.1 - 0.017 14.5 0.0 2.9 7.2 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_6 PF12774.7 EKX39675.1 - 0.045 12.7 0.0 0.12 11.3 0.0 1.6 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region AAA_29 PF13555.6 EKX39675.1 - 0.061 13.1 0.0 11 5.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain CbiA PF01656.23 EKX39675.1 - 0.086 12.9 0.0 6.5 6.8 0.0 2.8 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 EKX39675.1 - 0.088 12.7 0.0 7.7 6.4 0.0 3.1 3 0 0 3 3 2 0 NTPase Hpr_kinase_C PF07475.12 EKX39675.1 - 0.089 12.3 0.0 2 7.9 0.0 2.8 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain Rad17 PF03215.15 EKX39675.1 - 0.1 12.5 0.0 2.2 8.2 0.0 2.8 2 0 0 2 2 2 0 Rad17 P-loop domain TIP49 PF06068.13 EKX39675.1 - 0.15 11.2 5.7 0.32 10.1 0.0 2.9 4 0 0 4 4 4 0 TIP49 P-loop domain ATPase_2 PF01637.18 EKX39675.1 - 0.16 11.9 2.2 13 5.6 0.0 3.9 4 1 0 5 5 4 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 EKX39675.1 - 0.27 11.7 1.7 35 4.8 0.0 3.4 3 1 1 4 4 3 0 AAA domain ResIII PF04851.15 EKX39675.1 - 0.29 11.1 1.2 5.1 7.1 0.0 3.2 5 0 0 5 5 2 0 Type III restriction enzyme, res subunit SPRY PF00622.28 EKX39676.1 - 8.7e-08 32.3 0.1 1.9e-07 31.2 0.0 1.6 2 0 0 2 2 2 1 SPRY domain Neuralized PF07177.12 EKX39676.1 - 0.00028 20.9 0.0 0.0051 16.8 0.0 2.4 2 1 0 2 2 2 1 Neuralized PIG-H PF10181.9 EKX39677.1 - 9.4e-17 60.6 0.3 2e-16 59.6 0.3 1.5 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Glyco_trans_1_2 PF13524.6 EKX39678.1 - 6.9e-10 39.2 0.2 3e-09 37.1 0.1 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF563 PF04577.14 EKX39678.1 - 3e-06 27.5 0.2 0.00013 22.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF563) DUF2465 PF10239.9 EKX39679.1 - 4.8e-24 85.2 0.4 9e-24 84.3 0.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2465) Prp18 PF02840.15 EKX39681.1 - 0.0033 17.5 0.5 0.015 15.3 0.0 2.4 3 1 1 4 4 4 1 Prp18 domain Ets PF00178.22 EKX39681.1 - 0.1 13.0 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Ets-domain TOM20_plant PF06552.12 EKX39682.1 - 0.00067 19.4 2.3 0.0012 18.6 2.3 1.4 1 0 0 1 1 1 1 Plant specific mitochondrial import receptor subunit TOM20 GM_CSF PF01109.17 EKX39682.1 - 0.13 12.4 0.7 1.4 9.1 0.0 2.5 2 1 1 3 3 3 0 Granulocyte-macrophage colony-stimulating factor PARP PF00644.20 EKX39683.1 - 2.7e-09 36.9 0.0 5e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Mis12 PF05859.12 EKX39683.1 - 3.2 7.8 6.3 2.5 8.1 4.2 1.9 2 0 0 2 2 2 0 Mis12 protein DUF1664 PF07889.12 EKX39683.1 - 4.9 7.2 7.4 3.4 7.7 3.5 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Ribosomal_L22e PF01776.17 EKX39684.1 - 1.8e-43 147.4 4.7 2.2e-43 147.1 4.7 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family Pkinase PF00069.25 EKX39685.1 - 2.4e-47 161.5 1.6 5.6e-47 160.3 1.6 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX39685.1 - 9.2e-25 87.4 0.2 5.8e-24 84.8 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX39685.1 - 4.7e-05 22.8 0.1 0.00083 18.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 EKX39685.1 - 0.001 18.7 1.1 0.052 13.1 1.1 2.5 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 EKX39685.1 - 0.027 14.4 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX39685.1 - 0.054 12.3 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase p25-alpha PF05517.12 EKX39685.1 - 0.23 11.6 2.3 0.42 10.8 2.3 1.4 1 0 0 1 1 1 0 p25-alpha KinB_sensor PF16767.5 EKX39686.1 - 0.045 14.2 1.5 0.43 11.1 0.3 2.7 2 1 1 3 3 3 0 Sensor domain of alginate biosynthesis sensor protein KinB CAP_N PF01213.19 EKX39686.1 - 1.3 8.5 6.3 13 5.1 5.7 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Kinesin PF00225.23 EKX39687.1 - 9.7e-123 409.3 0.3 1.4e-122 408.8 0.3 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX39687.1 - 3.7e-27 95.1 0.0 6.9e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Kinesin_assoc PF16183.5 EKX39687.1 - 3.8e-06 27.2 5.7 6.1e-05 23.2 1.1 2.2 2 0 0 2 2 2 2 Kinesin-associated PIF1 PF05970.14 EKX39687.1 - 0.045 12.9 1.1 0.11 11.6 0.0 2.0 2 0 0 2 2 2 0 PIF1-like helicase DUF87 PF01935.17 EKX39687.1 - 0.91 9.6 4.8 15 5.6 0.0 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain GDPD PF03009.17 EKX39689.1 - 4.6e-26 92.1 0.0 5.2e-26 91.9 0.0 1.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.19 EKX39689.1 - 0.039 13.6 0.1 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 Phosphatidylinositol-specific phospholipase C, X domain SHE3 PF17078.5 EKX39690.1 - 0.00011 21.9 1.7 0.00023 20.9 1.7 1.4 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Plant_NMP1 PF06694.11 EKX39690.1 - 0.00096 18.3 0.1 0.0016 17.6 0.1 1.3 1 0 0 1 1 1 1 Plant nuclear matrix protein 1 (NMP1) Peptidase_S10 PF00450.22 EKX39690.1 - 0.019 14.4 1.3 0.022 14.2 0.6 1.4 2 0 0 2 2 2 0 Serine carboxypeptidase Nod1 PF17114.5 EKX39690.1 - 0.061 13.5 0.4 0.23 11.6 0.3 2.0 2 1 0 2 2 2 0 Gef2-related medial cortical node protein Nod1 CLZ PF16526.5 EKX39690.1 - 0.14 12.5 3.6 0.57 10.6 1.0 3.1 2 2 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF745 PF05335.13 EKX39690.1 - 0.51 10.0 3.1 1 9.0 3.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) UPF0060 PF02694.15 EKX39694.1 - 1.2e-28 99.5 9.1 1.3e-28 99.3 9.1 1.0 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family RibD_C PF01872.17 EKX39695.1 - 4.3e-20 72.4 0.0 5.4e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain Ala_racemase_N PF01168.20 EKX39696.1 - 9.4e-35 120.2 0.0 1.4e-34 119.7 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Ala_racemase_C PF00842.21 EKX39696.1 - 1e-11 44.7 0.0 1.9e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Alanine racemase, C-terminal domain Orf78 PF06024.12 EKX39697.1 - 0.0019 18.4 1.1 0.011 16.0 1.1 2.3 1 0 0 1 1 1 1 Orf78 (ac78) IFP_35_N PF07334.13 EKX39697.1 - 0.0029 17.6 0.5 0.0029 17.6 0.5 3.4 2 1 1 3 3 3 1 Interferon-induced 35 kDa protein (IFP 35) N-terminus ATG16 PF08614.11 EKX39697.1 - 0.0036 17.5 11.2 0.0036 17.5 11.2 3.2 1 1 1 3 3 3 1 Autophagy protein 16 (ATG16) Imm74 PF15603.6 EKX39697.1 - 0.014 15.5 0.0 0.041 14.1 0.0 1.8 1 0 0 1 1 1 0 Immunity protein 74 DUF898 PF05987.13 EKX39697.1 - 0.03 13.4 5.2 0.043 12.9 5.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF948 PF06103.11 EKX39697.1 - 0.44 10.8 6.2 7.5 6.9 0.0 4.3 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF2244 PF10003.9 EKX39697.1 - 3.4 7.3 6.1 2 8.1 3.1 2.1 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) NOA36 PF06524.12 EKX39697.1 - 4.4 6.5 28.6 11 5.2 28.6 1.6 1 0 0 1 1 1 0 NOA36 protein DUF16 PF01519.16 EKX39697.1 - 4.5 7.8 14.2 5.8 7.5 2.8 2.9 3 0 0 3 3 3 0 Protein of unknown function DUF16 Pex24p PF06398.11 EKX39697.1 - 9.6 5.1 8.5 1.2 8.1 3.9 1.8 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin CUB PF00431.20 EKX39698.1 - 3e-07 30.7 0.3 1.6e-06 28.4 0.0 2.5 2 0 0 2 2 2 1 CUB domain MbtH PF03621.13 EKX39698.1 - 0.0052 16.2 10.5 1.6 8.2 0.2 6.2 6 0 0 6 6 6 1 MbtH-like protein Stealth_CR4 PF17103.5 EKX39698.1 - 0.038 13.9 0.2 2.1 8.3 0.1 2.5 2 0 0 2 2 2 0 Stealth protein CR4, conserved region 4 LRR_6 PF13516.6 EKX39699.1 - 7.9e-25 84.8 10.5 0.00013 21.7 0.0 5.1 5 0 0 5 5 5 5 Leucine Rich repeat LRR_4 PF12799.7 EKX39699.1 - 7.8e-10 38.9 6.9 0.00018 21.8 0.5 3.7 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX39699.1 - 1.8e-07 30.7 0.2 1.6 9.6 0.0 4.9 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_8 PF13855.6 EKX39699.1 - 7.8e-06 25.6 10.4 0.052 13.3 0.8 4.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_2 PF07723.13 EKX39699.1 - 0.019 15.6 0.5 27 5.6 0.0 3.7 4 0 0 4 4 4 0 Leucine Rich Repeat Ank_4 PF13637.6 EKX39700.1 - 2.7e-05 24.6 0.0 0.0071 16.9 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX39700.1 - 0.027 14.8 0.0 4.6 7.7 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX39700.1 - 0.038 14.6 0.0 0.52 10.9 0.0 2.6 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) IQ PF00612.27 EKX39701.1 - 2.7e-28 95.1 69.2 0.0022 17.6 1.3 13.1 12 0 0 12 12 12 11 IQ calmodulin-binding motif OmpH PF03938.14 EKX39701.1 - 0.79 10.1 10.4 7.3 6.9 0.3 3.5 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) LRR_9 PF14580.6 EKX39702.1 - 1.6e-08 34.3 0.1 3.3e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 Leucine-rich repeat IQ PF00612.27 EKX39702.1 - 3.2e-06 26.5 8.0 0.022 14.5 0.1 4.0 3 0 0 3 3 3 2 IQ calmodulin-binding motif LRR_8 PF13855.6 EKX39702.1 - 4.3e-06 26.4 11.6 0.00013 21.6 1.4 2.0 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EKX39702.1 - 4.5e-05 23.7 2.9 0.045 14.2 0.4 2.4 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) AAA PF00004.29 EKX39704.1 - 2.7e-12 47.3 0.0 9.9e-12 45.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EKX39704.1 - 0.0016 18.2 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EKX39704.1 - 0.0035 16.6 1.1 0.26 10.5 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain IQ PF00612.27 EKX39704.1 - 0.0078 15.9 0.1 0.025 14.3 0.1 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif AAA_5 PF07728.14 EKX39704.1 - 0.024 14.7 0.0 0.059 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EKX39704.1 - 0.028 14.8 0.1 0.23 11.8 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain ATPase_2 PF01637.18 EKX39704.1 - 0.034 14.0 1.2 0.081 12.8 0.0 2.2 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea IPT PF01745.16 EKX39704.1 - 0.06 12.7 0.1 0.38 10.1 0.0 2.3 3 0 0 3 3 3 0 Isopentenyl transferase AAA_14 PF13173.6 EKX39704.1 - 0.062 13.3 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EKX39704.1 - 0.082 13.3 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase LRR_4 PF12799.7 EKX39705.1 - 1.4e-22 79.3 27.9 7.5e-08 32.6 1.8 5.2 4 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX39705.1 - 2e-13 49.9 30.7 3.3e-08 33.2 6.5 5.1 1 1 3 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 EKX39705.1 - 2.4e-13 49.9 12.5 8.3e-12 44.9 5.7 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 EKX39705.1 - 0.21 11.7 22.6 1.6 8.9 0.1 6.6 7 0 0 7 7 7 0 Leucine Rich repeat LRR_1 PF00560.33 EKX39705.1 - 1.6 9.5 27.3 26 5.9 0.2 7.3 6 1 0 6 6 6 0 Leucine Rich Repeat DUF892 PF05974.12 EKX39706.1 - 0.22 11.5 0.0 0.33 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF892) DUF3584 PF12128.8 EKX39707.1 - 0.055 11.0 2.3 0.072 10.6 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DASH_Spc34 PF08657.10 EKX39707.1 - 0.064 13.0 0.2 0.078 12.8 0.2 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 FapA PF03961.13 EKX39707.1 - 0.14 10.7 0.4 0.17 10.4 0.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3073 PF11273.8 EKX39707.1 - 4.1 8.2 6.6 11 6.9 6.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3073) DSPc PF00782.20 EKX39709.1 - 1.2e-17 64.0 0.0 1.4e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 EKX39709.1 - 6.8e-05 22.5 0.0 7.9e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EKX39709.1 - 0.00017 21.2 0.0 0.00019 21.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EKX39709.1 - 0.019 15.0 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.12 EKX39709.1 - 0.085 12.5 0.0 0.15 11.7 0.0 1.5 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) HECT PF00632.25 EKX39710.1 - 8.1e-56 189.8 0.0 1.1e-55 189.3 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Laminin_G_3 PF13385.6 EKX39711.1 - 6.6e-05 23.1 0.0 0.0001 22.5 0.0 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Membralin PF09746.9 EKX39712.1 - 5.1e-09 35.7 7.6 1.6e-07 30.8 7.6 2.2 1 1 0 1 1 1 1 Tumour-associated protein YEATS PF03366.16 EKX39713.1 - 0.18 11.8 0.2 0.95 9.5 0.1 1.9 2 0 0 2 2 2 0 YEATS family zf-CCCH PF00642.24 EKX39714.1 - 7.4e-12 44.9 10.9 8.7e-06 25.5 0.2 2.2 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EKX39714.1 - 3.6e-11 42.7 15.9 3.7e-07 30.0 2.8 2.2 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 EKX39714.1 - 1.2e-08 35.7 9.4 5.7e-05 23.8 2.1 2.0 1 1 1 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 EKX39714.1 - 1.9e-08 34.5 13.1 1.1e-05 25.7 1.1 2.3 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 EKX39714.1 - 6.6e-06 25.8 11.6 0.00015 21.5 0.3 2.2 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EKX39714.1 - 0.0003 21.0 7.2 0.12 12.5 0.9 2.1 1 1 1 2 2 2 2 Zinc-finger containing family Pkinase PF00069.25 EKX39715.1 - 1.4e-64 218.0 0.0 1.6e-64 217.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX39715.1 - 5.8e-37 127.4 0.0 7.6e-37 127.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX39715.1 - 5.4e-11 42.3 0.0 8e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EKX39715.1 - 0.0014 17.5 0.0 0.0029 16.4 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EKX39715.1 - 0.0089 15.4 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX39715.1 - 0.018 14.9 0.1 0.19 11.6 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 EKX39715.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 EKX39715.1 - 0.13 11.9 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF5360 PF17314.2 EKX39715.1 - 0.17 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5360) TEP1_N PF05386.11 EKX39716.1 - 0.25 10.9 0.4 24 4.6 0.1 2.7 2 0 0 2 2 2 0 TEP1 N-terminal domain URO-D PF01208.17 EKX39717.1 - 1.3e-112 376.4 0.0 1.5e-112 376.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) T3RM_EcoP15I_C PF18273.1 EKX39717.1 - 0.17 12.2 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 Type III R-M EcoP15I C-terminal domain FH2 PF02181.23 EKX39718.1 - 5.4e-79 266.0 9.9 6.2e-79 265.8 9.9 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain DUF1798 PF08807.10 EKX39718.1 - 0.062 13.4 2.8 0.068 13.3 0.5 2.2 2 0 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) PilJ PF13675.6 EKX39718.1 - 0.097 12.7 0.0 1.5 8.8 0.0 2.7 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Sas10_Utp3 PF04000.15 EKX39718.1 - 1.1 9.9 4.9 0.54 10.9 0.3 2.9 3 1 0 3 3 3 0 Sas10/Utp3/C1D family Jnk-SapK_ap_N PF09744.9 EKX39718.1 - 7.1 6.8 6.8 1.7 8.9 0.9 2.4 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 TPR_1 PF00515.28 EKX39720.1 - 0.00097 18.9 1.5 0.018 14.9 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat PDZ_3 PF17815.1 EKX39720.1 - 0.0016 18.3 0.2 0.014 15.3 0.2 2.3 2 0 0 2 2 2 1 PDZ domain cNMP_binding PF00027.29 EKX39720.1 - 0.0026 17.8 0.0 0.0062 16.6 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DMAP_binding PF06464.11 EKX39720.1 - 0.0052 17.6 1.3 0.1 13.4 1.4 2.7 2 1 0 2 2 2 1 DMAP1-binding Domain TPR_12 PF13424.6 EKX39720.1 - 0.0098 16.2 1.6 0.13 12.5 0.3 3.3 2 1 0 2 2 2 1 Tetratricopeptide repeat SHOCT PF09851.9 EKX39720.1 - 0.011 15.5 0.2 0.04 13.7 0.2 2.1 1 0 0 1 1 1 0 Short C-terminal domain TPR_7 PF13176.6 EKX39720.1 - 0.019 15.0 0.5 1.9 8.7 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EKX39720.1 - 0.042 14.0 5.9 0.079 13.1 0.3 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX39720.1 - 0.07 14.0 0.6 1.8 9.6 0.3 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX39720.1 - 0.1 12.9 2.9 0.62 10.4 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 EKX39720.1 - 0.4 11.0 2.9 8.4 6.9 0.1 3.5 3 0 0 3 3 3 0 PPR repeat CDC37_N PF03234.14 EKX39720.1 - 1.4 9.9 5.1 5.8 7.8 5.1 2.0 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Zn_clus PF00172.18 EKX39721.1 - 1.2e-20 73.3 47.9 3e-08 33.6 11.4 3.3 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain p47_phox_C PF08944.11 EKX39722.1 - 5.1e-05 22.6 53.3 0.32 10.4 0.4 7.2 7 0 0 7 7 7 7 NADPH oxidase subunit p47Phox, C terminal domain Zn_clus PF00172.18 EKX39723.1 - 4.1e-21 74.8 48.5 3e-08 33.6 11.4 3.3 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 EKX39724.1 - 1.2e-20 73.3 47.9 3e-08 33.6 11.4 3.3 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 EKX39725.1 - 4.9e-21 74.6 48.5 3.2e-08 33.6 11.4 3.3 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 EKX39726.1 - 1.8e-07 31.2 12.8 1.8e-07 31.2 12.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 EKX39727.1 - 4.1e-21 74.8 48.5 3e-08 33.6 11.4 3.3 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain OrgA_MxiK PF09482.10 EKX39728.1 - 0.0073 16.2 0.1 4 7.3 0.0 2.5 2 1 0 2 2 2 2 Bacterial type III secretion apparatus protein (OrgA_MxiK) SF3a60_bindingd PF12108.8 EKX39729.1 - 2e-05 24.4 1.2 34 4.4 0.0 5.6 6 0 0 6 6 6 0 Splicing factor SF3a60 binding domain Phage_terminase PF10668.9 EKX39729.1 - 0.00042 20.3 6.7 56 3.8 0.0 5.8 5 0 0 5 5 5 0 Phage terminase small subunit OrgA_MxiK PF09482.10 EKX39729.1 - 0.078 12.8 13.3 18 5.1 0.4 4.8 4 0 0 4 4 4 0 Bacterial type III secretion apparatus protein (OrgA_MxiK) PCIF1_WW PF12237.8 EKX39729.1 - 0.13 11.8 1.6 32 4.1 0.0 3.7 4 0 0 4 4 4 0 Phosphorylated CTD interacting factor 1 WW domain PUCC PF03209.15 EKX39729.1 - 0.2 10.7 2.5 12 4.7 0.2 2.8 2 0 0 2 2 2 0 PUCC protein Paz_1 PF18349.1 EKX39729.1 - 2.7 8.0 17.0 29 4.7 0.2 6.0 5 0 0 5 5 5 0 PAZ domain DHHC PF01529.20 EKX39730.1 - 7.7e-22 77.8 10.8 8.1e-22 77.8 10.8 1.0 1 0 0 1 1 1 1 DHHC palmitoyltransferase MRAP PF15183.6 EKX39730.1 - 0.003 17.5 0.1 0.003 17.4 0.1 1.2 1 0 0 1 1 1 1 Melanocortin-2 receptor accessory protein family Cadherin_4 PF17803.1 EKX39731.1 - 0.057 14.0 4.5 10 6.8 0.1 4.7 4 0 0 4 4 4 0 Bacterial cadherin-like domain PP2C PF00481.21 EKX39732.1 - 3.2e-33 115.5 0.0 6.4e-33 114.5 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EKX39732.1 - 1e-05 25.5 0.1 0.00028 20.9 0.0 2.2 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) DUF2431 PF10354.9 EKX39733.1 - 8.1e-34 117.3 0.0 1.2e-33 116.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) FDX-ACB PF03147.14 EKX39733.1 - 2e-07 31.3 0.2 5.8e-07 29.8 0.2 1.7 1 1 0 1 1 1 1 Ferredoxin-fold anticodon binding domain MTS PF05175.14 EKX39733.1 - 0.00017 21.2 0.0 0.0038 16.8 0.0 2.3 2 1 1 3 3 3 1 Methyltransferase small domain DDE_Tnp_ISL3 PF01610.17 EKX39733.1 - 0.085 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Transposase GAF PF01590.26 EKX39735.1 - 7.1e-19 68.8 0.6 2.8e-08 34.5 0.1 3.7 3 0 0 3 3 3 3 GAF domain GAF_2 PF13185.6 EKX39735.1 - 1.5e-09 38.3 10.5 1.3e-06 28.8 0.1 5.3 7 1 0 7 7 7 3 GAF domain GAF_3 PF13492.6 EKX39735.1 - 1.1e-05 25.8 5.3 0.021 15.2 0.0 6.1 6 1 0 6 6 6 2 GAF domain PWI PF01480.17 EKX39736.1 - 2.5e-24 85.4 0.0 3.3e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 PWI domain Glyco_transf_64 PF09258.10 EKX39738.1 - 5.9e-43 146.9 0.0 1.2e-42 145.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain EF1_GNE PF00736.19 EKX39739.1 - 4.4e-26 90.9 2.4 6.6e-26 90.3 2.4 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain TMEM223 PF14640.6 EKX39741.1 - 0.044 13.9 0.0 0.056 13.6 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 223 Guanylate_cyc PF00211.20 EKX39742.1 - 1.2e-17 64.1 0.0 1.4e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 EKX39743.1 - 4e-18 65.7 0.0 5.6e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Aminotran_1_2 PF00155.21 EKX39744.1 - 4.7e-55 187.2 0.0 5.7e-43 147.5 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class I and II Aminotran_3 PF00202.21 EKX39744.1 - 0.015 14.0 0.0 0.021 13.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III Alliinase_C PF04864.13 EKX39744.1 - 0.075 11.9 0.0 0.12 11.2 0.0 1.3 1 1 0 1 1 1 0 Allinase HEM4 PF02602.15 EKX39744.1 - 0.16 11.3 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD Beta_elim_lyase PF01212.21 EKX39744.1 - 0.19 11.0 0.0 0.42 9.8 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase ubiquitin PF00240.23 EKX39747.1 - 9.3e-05 22.1 0.1 0.00028 20.6 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family zf-H2C2_5 PF13909.6 EKX39747.1 - 0.0054 16.5 0.8 0.0096 15.7 0.8 1.4 1 0 0 1 1 1 1 C2H2-type zinc-finger domain Sin_N PF04801.13 EKX39747.1 - 0.032 13.5 0.4 0.044 13.0 0.4 1.2 1 0 0 1 1 1 0 Sin-like protein conserved region Phage_tail_S PF05069.13 EKX39747.1 - 0.11 12.4 0.6 0.39 10.5 0.6 1.9 1 1 1 2 2 2 0 Phage virion morphogenesis family TilS PF09179.11 EKX39747.1 - 0.32 11.5 2.0 1 9.9 0.9 2.2 2 0 0 2 2 2 0 TilS substrate binding domain SNARE_assoc PF09335.11 EKX39748.1 - 3.3e-17 63.1 7.3 7.6e-17 61.9 7.3 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein PelG PF16933.5 EKX39748.1 - 0.0023 16.9 1.9 0.0035 16.3 1.9 1.2 1 0 0 1 1 1 1 Putative exopolysaccharide Exporter (EPS-E) Colicin_V PF02674.16 EKX39748.1 - 0.033 14.1 3.0 0.11 12.5 3.0 1.9 1 0 0 1 1 1 0 Colicin V production protein DUF4014 PF13198.6 EKX39748.1 - 0.16 12.3 2.0 0.27 11.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) PKD_channel PF08016.12 EKX39750.1 - 1e-62 212.2 19.1 2e-62 211.3 19.1 1.4 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 EKX39750.1 - 7.1e-06 25.4 28.7 7.1e-06 25.4 28.7 1.7 2 0 0 2 2 2 1 Ion transport protein HAD_2 PF13419.6 EKX39751.1 - 2e-09 37.8 0.0 4.4e-09 36.7 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EKX39751.1 - 1.8e-08 34.9 0.0 5.3e-08 33.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EKX39751.1 - 0.0049 17.3 0.0 0.033 14.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3420 PF11900.8 EKX39754.1 - 0.12 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3420) Cation_efflux PF01545.21 EKX39756.1 - 4.3e-24 85.3 7.4 5.4e-24 85.0 7.4 1.1 1 0 0 1 1 1 1 Cation efflux family zf-3CxxC PF13695.6 EKX39756.1 - 0.046 14.2 0.1 0.14 12.6 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding domain PAP2 PF01569.21 EKX39757.1 - 2.7e-11 43.4 6.3 1.5e-10 41.0 6.3 2.0 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 EKX39757.1 - 0.033 14.3 0.8 3.6 7.7 0.0 2.4 1 1 0 2 2 2 0 Divergent PAP2 family TMEM252 PF15664.5 EKX39757.1 - 0.22 11.2 0.2 0.36 10.6 0.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 252 family DUF4203 PF13886.6 EKX39757.1 - 0.53 9.9 12.5 1.3 8.7 9.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4203) IF2_N PF04760.15 EKX39758.1 - 0.00088 19.0 0.8 0.0016 18.2 0.3 1.6 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region DUF2613 PF11021.8 EKX39759.1 - 0.14 12.3 0.2 0.28 11.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) CSN8_PSD8_EIF3K PF10075.9 EKX39760.1 - 1.3e-20 73.9 0.0 1.8e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 EKX39760.1 - 0.0019 18.7 0.2 0.0031 18.0 0.2 1.6 1 1 0 1 1 1 1 PCI domain RWP-RK PF02042.15 EKX39761.1 - 1.1e-09 38.2 0.0 1.6e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain HEAT_2 PF13646.6 EKX39762.1 - 4.3e-15 55.9 9.9 8.3e-07 29.3 0.7 4.9 2 1 3 5 5 5 4 HEAT repeats HEAT PF02985.22 EKX39762.1 - 4.5e-05 23.4 5.8 12 6.4 0.0 5.9 5 0 0 5 5 5 1 HEAT repeat Adaptin_N PF01602.20 EKX39762.1 - 0.00053 18.7 2.3 0.018 13.6 1.7 2.9 3 1 1 4 4 4 1 Adaptin N terminal region Cnd1 PF12717.7 EKX39762.1 - 0.0011 19.0 1.3 0.0086 16.1 0.1 2.7 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EKX39762.1 - 0.0016 18.9 7.4 0.87 10.2 0.0 5.5 3 2 4 7 7 7 1 HEAT-like repeat RTP1_C1 PF10363.9 EKX39762.1 - 0.0028 17.8 0.3 1.1 9.4 0.1 3.8 1 1 1 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF5578 PF17741.1 EKX39762.1 - 0.028 13.9 0.7 4 6.8 0.1 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5578) DUF4042 PF13251.6 EKX39762.1 - 0.071 12.8 0.2 2.2 7.9 0.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4042) MMS19_N PF14500.6 EKX39762.1 - 0.089 12.4 0.1 11 5.5 0.0 2.8 2 1 1 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Nipped-B_C PF12830.7 EKX39762.1 - 0.14 12.1 1.5 0.89 9.5 0.1 2.8 3 1 0 3 3 3 0 Sister chromatid cohesion C-terminus Pkinase PF00069.25 EKX39765.1 - 2.4e-70 236.9 0.0 3.2e-70 236.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX39765.1 - 2.8e-36 125.1 0.0 4e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX39765.1 - 6.9e-07 28.9 0.0 1.2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EKX39765.1 - 1.9e-06 26.9 0.2 3.2e-06 26.2 0.2 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EKX39765.1 - 0.011 15.1 0.1 0.032 13.6 0.1 1.8 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Heme_oxygenase PF01126.20 EKX39766.1 - 6.7e-40 137.1 0.6 7.8e-40 136.8 0.6 1.0 1 0 0 1 1 1 1 Heme oxygenase ThrE PF06738.12 EKX39767.1 - 0.017 14.5 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Putative threonine/serine exporter CENP-H PF05837.12 EKX39767.1 - 0.026 14.9 0.7 0.12 12.8 0.1 2.0 2 0 0 2 2 2 0 Centromere protein H (CENP-H) UPF0184 PF03670.13 EKX39767.1 - 0.085 13.3 0.8 0.19 12.1 0.8 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Hemagglutinin PF00509.18 EKX39767.1 - 0.12 10.8 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Haemagglutinin RTBV_P46 PF06216.11 EKX39767.1 - 0.19 10.6 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein KxDL PF10241.9 EKX39767.1 - 0.31 11.4 0.2 0.31 11.4 0.2 1.9 2 1 0 2 2 2 0 Uncharacterized conserved protein F-box-like PF12937.7 EKX39768.1 - 0.00029 20.7 1.3 0.00044 20.1 0.1 2.0 2 0 0 2 2 2 1 F-box-like IQ PF00612.27 EKX39769.1 - 0.036 13.8 0.1 0.091 12.6 0.1 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif LEA_6 PF10714.9 EKX39769.1 - 0.2 11.7 0.9 0.41 10.8 0.9 1.4 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 Sec15 PF04091.12 EKX39770.1 - 4.5e-24 85.4 1.8 1.4e-20 73.9 1.1 3.7 2 1 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec34 PF04136.15 EKX39770.1 - 0.51 10.2 3.0 51 3.7 0.1 3.6 3 0 0 3 3 3 0 Sec34-like family Trp_Tyr_perm PF03222.13 EKX39772.1 - 2.7e-15 56.3 6.8 6.8e-10 38.5 3.3 2.1 2 0 0 2 2 2 2 Tryptophan/tyrosine permease family THOC7 PF05615.13 EKX39773.1 - 1.8e-05 25.1 8.7 4.9e-05 23.6 8.7 1.7 1 0 0 1 1 1 1 Tho complex subunit 7 HWE_HK PF07536.14 EKX39773.1 - 0.22 12.2 1.3 0.64 10.8 0.4 2.2 2 0 0 2 2 2 0 HWE histidine kinase HeLo PF14479.6 EKX39773.1 - 1.2 8.9 6.8 1.4 8.7 3.1 2.2 2 0 0 2 2 2 0 Prion-inhibition and propagation AviRa PF11599.8 EKX39773.1 - 1.3 8.4 3.9 0.81 9.1 2.0 1.5 2 0 0 2 2 2 0 RRNA methyltransferase AviRa Ax_dynein_light PF10211.9 EKX39773.1 - 6.7 6.6 13.0 13 5.7 13.0 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain DUF4633 PF15464.6 EKX39773.1 - 8.2 6.6 7.1 28 4.9 2.4 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4633) Trp_Tyr_perm PF03222.13 EKX39774.1 - 1.4e-10 40.8 10.2 9.5e-10 38.1 10.2 2.0 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Inhibitor_I34 PF10466.9 EKX39775.1 - 0.00025 21.6 1.6 0.00025 21.6 1.6 2.0 2 1 0 2 2 2 1 Saccharopepsin inhibitor I34 nec1 PF10379.9 EKX39775.1 - 0.053 13.0 0.1 0.08 12.4 0.1 1.2 1 0 0 1 1 1 0 Virulence protein nec1 Ribosomal_L7Ae PF01248.26 EKX39777.1 - 1.8e-08 34.0 0.0 3.5e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EKX39777.1 - 0.0023 18.0 0.0 0.0039 17.3 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 AP3D1 PF06375.11 EKX39777.1 - 0.017 15.4 1.9 0.025 14.8 1.9 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 fn3_PAP PF17808.1 EKX39778.1 - 0.16 12.1 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Fn3-like domain from Purple Acid Phosphatase Ribosomal_60s PF00428.19 EKX39779.1 - 0.00075 20.0 5.7 0.0008 19.9 5.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein AP3D1 PF06375.11 EKX39779.1 - 0.00084 19.6 3.6 0.00084 19.6 3.6 1.1 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 Coilin_N PF15862.5 EKX39779.1 - 0.056 13.3 4.7 0.06 13.1 4.7 1.1 1 0 0 1 1 1 0 Coilin N-terminus U-box PF04564.15 EKX39780.1 - 1.2e-18 67.0 0.1 1.9e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX39780.1 - 2.9e-05 23.8 0.0 7.2e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 EKX39780.1 - 0.0003 20.9 0.0 0.00066 19.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 EKX39780.1 - 0.001 19.0 0.1 0.0028 17.7 0.0 1.8 2 0 0 2 2 2 1 RING-type zinc-finger Rubredoxin PF00301.20 EKX39780.1 - 0.23 11.5 1.0 0.73 9.9 1.0 1.8 1 1 0 1 1 1 0 Rubredoxin Ceramidase PF05875.12 EKX39781.1 - 6.4e-24 84.8 1.2 7.5e-24 84.6 1.2 1.1 1 0 0 1 1 1 1 Ceramidase CPP1-like PF11833.8 EKX39781.1 - 0.48 10.0 1.4 4 7.1 0.8 2.0 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like PAS_9 PF13426.7 EKX39782.1 - 1.3e-08 35.0 0.0 0.0031 17.7 0.0 2.1 2 0 0 2 2 2 2 PAS domain FlaC_arch PF05377.11 EKX39783.1 - 0.11 12.8 3.3 4.9 7.6 0.1 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Mod_r PF07200.13 EKX39783.1 - 6.3 6.9 20.8 0.052 13.6 2.4 2.8 2 1 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Allexi_40kDa PF05549.11 EKX39783.1 - 9.5 5.6 9.7 0.33 10.4 2.1 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF4200 PF13863.6 EKX39784.1 - 1.5e-35 122.2 25.1 1.5e-35 122.2 25.1 4.8 4 0 0 4 4 4 2 Domain of unknown function (DUF4200) DUF4279 PF14106.6 EKX39784.1 - 0.073 13.3 3.6 1.3 9.3 0.2 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) DUF1180 PF06679.12 EKX39784.1 - 1.2 9.5 8.5 6.2 7.2 8.5 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF4407 PF14362.6 EKX39784.1 - 3.3 7.0 44.0 0.058 12.7 7.7 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Nucleotid_trans PF03407.16 EKX39786.1 - 2.3e-17 63.7 0.0 2.9e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF1580 PF07618.11 EKX39787.1 - 0.039 13.6 0.1 14 5.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1580) DUF1645 PF07816.11 EKX39787.1 - 7.3 7.1 14.1 34 4.9 10.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1645) EF-hand_1 PF00036.32 EKX39789.1 - 5.4e-26 88.2 13.3 3.9e-08 32.3 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EKX39789.1 - 1.2e-24 86.5 8.4 8.1e-12 45.4 2.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX39789.1 - 5.7e-22 75.7 5.2 1.9e-08 33.6 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 EKX39789.1 - 3.9e-20 71.5 12.3 9.2e-13 47.8 0.5 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EKX39789.1 - 3.2e-15 54.8 9.5 2.6e-05 23.5 0.1 4.0 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 EKX39789.1 - 1e-13 51.4 0.4 1.2e-06 28.8 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EKX39789.1 - 6e-05 22.9 3.9 0.26 11.3 0.0 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 EKX39789.1 - 8e-05 22.9 0.5 0.23 11.8 0.1 2.3 1 1 1 2 2 2 2 EF-hand domain TerB PF05099.13 EKX39789.1 - 0.0015 18.5 1.2 0.021 14.8 0.5 2.1 2 0 0 2 2 2 1 Tellurite resistance protein TerB Caleosin PF05042.13 EKX39789.1 - 0.015 15.3 0.7 2.4 8.1 0.0 3.3 1 1 3 4 4 4 0 Caleosin related protein SurA_N_3 PF13624.6 EKX39789.1 - 0.036 13.8 0.3 2 8.2 0.1 2.1 2 0 0 2 2 2 0 SurA N-terminal domain DUF3911 PF13050.6 EKX39789.1 - 0.05 13.7 0.6 0.23 11.6 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3911) LETM1 PF07766.13 EKX39789.1 - 0.064 12.6 1.0 0.16 11.3 0.3 2.0 1 1 2 3 3 3 0 LETM1-like protein DUF2293 PF10056.9 EKX39789.1 - 0.064 13.5 0.4 0.79 10.0 0.1 2.5 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2293) Rad33 PF08730.10 EKX39789.1 - 0.069 13.1 0.2 0.21 11.6 0.2 1.7 1 1 1 2 2 2 0 Rad33 Dockerin_1 PF00404.18 EKX39789.1 - 0.077 13.2 0.1 1.3 9.3 0.1 2.4 2 0 0 2 2 2 0 Dockerin type I domain Phage_TAC_12 PF12363.8 EKX39789.1 - 0.083 13.3 0.9 3.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC RTX_C PF08339.10 EKX39789.1 - 0.099 12.7 0.2 0.13 12.4 0.2 1.3 1 1 0 1 1 1 0 RTX C-terminal domain DUF1296 PF06972.11 EKX39789.1 - 0.21 11.7 1.6 3.1 8.0 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1296) PDZ PF00595.24 EKX39790.1 - 1.5e-13 50.9 0.1 4e-06 27.1 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EKX39790.1 - 2.4e-13 49.7 0.0 1e-08 34.9 0.0 2.8 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX39790.1 - 7.5e-08 32.6 0.0 0.015 15.6 0.0 2.9 2 0 0 2 2 2 2 PDZ domain EzrA PF06160.12 EKX39790.1 - 1.4e-05 23.5 51.3 0.00019 19.8 18.4 2.4 2 0 0 2 2 2 2 Septation ring formation regulator, EzrA ABC_tran_CTD PF16326.5 EKX39790.1 - 0.0046 17.2 1.0 0.0046 17.2 1.0 7.7 2 2 5 7 7 6 2 ABC transporter C-terminal domain Fez1 PF06818.15 EKX39790.1 - 0.011 16.2 70.2 1.7 9.1 23.1 4.0 1 1 2 3 3 3 0 Fez1 CALCOCO1 PF07888.11 EKX39790.1 - 0.014 14.3 72.5 0.062 12.2 31.5 3.3 2 1 1 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like Osmo_CC PF08946.10 EKX39790.1 - 0.058 13.6 0.1 0.058 13.6 0.1 5.5 5 1 0 5 5 4 0 Osmosensory transporter coiled coil ATG16 PF08614.11 EKX39790.1 - 0.19 11.9 75.9 0.36 11.0 3.2 5.0 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.12 EKX39790.1 - 0.23 11.9 20.7 2.5 8.6 1.2 5.4 5 1 0 5 5 4 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 EKX39790.1 - 0.26 10.6 50.3 2 7.7 16.2 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 EKX39790.1 - 0.34 10.9 16.5 4 7.5 0.8 4.7 3 2 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 EKX39790.1 - 0.92 9.6 34.3 0.27 11.3 2.0 5.2 3 2 1 5 5 5 0 Protein of unknown function (DUF1664) GAS PF13851.6 EKX39790.1 - 1.3 8.4 70.3 0.54 9.6 1.5 5.1 2 2 3 5 5 5 0 Growth-arrest specific micro-tubule binding CCDC144C PF14915.6 EKX39790.1 - 2.3 7.3 71.1 0.18 10.9 16.2 3.9 2 2 0 3 3 3 0 CCDC144C protein coiled-coil region DASH_Dam1 PF08653.10 EKX39790.1 - 3 7.7 4.5 11 6.0 0.0 3.9 4 0 0 4 4 4 0 DASH complex subunit Dam1 Laminin_II PF06009.12 EKX39790.1 - 3.1 7.8 47.2 1.7 8.7 2.1 6.2 2 2 3 6 6 6 0 Laminin Domain II Sharpin_PH PF16764.5 EKX39791.1 - 0.16 11.7 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 Sharpin PH domain Phosducin PF02114.16 EKX39793.1 - 0.00093 18.2 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 Phosducin PI3K_C2 PF00792.24 EKX39794.1 - 0.056 13.4 0.4 0.24 11.3 0.0 2.3 2 1 0 2 2 2 0 Phosphoinositide 3-kinase C2 PRIMA1 PF16101.5 EKX39794.1 - 0.21 11.6 0.4 0.39 10.7 0.4 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 NID PF07292.13 EKX39794.1 - 2.3 8.9 6.1 47 4.7 0.2 3.2 3 0 0 3 3 3 0 Nmi/IFP 35 domain (NID) Peptidase_M13_N PF05649.13 EKX39795.1 - 1.4e-66 225.8 0.0 1.8e-66 225.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 EKX39795.1 - 5.9e-59 199.1 0.1 1.2e-58 198.1 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M13 zf-C2H2_3 PF13878.6 EKX39797.1 - 0.11 12.4 0.7 0.2 11.5 0.7 1.4 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO Fz PF01392.22 EKX39798.1 - 2.7e-06 28.0 1.5 2.7e-06 28.0 1.5 1.7 2 0 0 2 2 2 1 Fz domain RWP-RK PF02042.15 EKX39799.1 - 4.7e-15 55.3 0.0 9e-15 54.4 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX39799.1 - 0.00031 20.5 0.2 0.0033 17.2 0.0 2.2 1 1 1 2 2 2 1 Bacterial regulatory protein, Fis family Peptidase_M16_C PF05193.21 EKX39800.1 - 1e-32 113.7 0.0 1.2e-15 58.0 0.0 3.5 3 1 0 3 3 3 3 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EKX39800.1 - 2.5e-23 82.7 0.1 1.4e-22 80.3 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Sigma70_r3 PF04539.16 EKX39800.1 - 0.025 14.7 0.7 4.5 7.5 0.4 3.6 4 0 0 4 4 4 0 Sigma-70 region 3 Pkinase PF00069.25 EKX39801.1 - 1.7e-72 244.0 0.0 2.1e-72 243.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX39801.1 - 9.5e-36 123.4 0.0 1.3e-35 123.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EKX39801.1 - 0.00055 19.0 0.0 0.00078 18.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EKX39801.1 - 0.0039 16.8 0.1 0.24 11.0 0.1 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EKX39801.1 - 0.011 15.0 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like AP3D1 PF06375.11 EKX39802.1 - 0.00041 20.6 0.4 0.00041 20.6 0.4 2.2 2 1 0 2 2 2 1 AP-3 complex subunit delta-1 Myc_N PF01056.18 EKX39802.1 - 0.022 14.7 3.1 0.022 14.7 3.1 1.9 2 0 0 2 2 2 0 Myc amino-terminal region DUF2201_N PF13203.6 EKX39802.1 - 7.5 6.1 9.3 12 5.4 3.6 2.3 2 0 0 2 2 2 0 Putative metallopeptidase domain SspB PF04386.13 EKX39802.1 - 8.3 6.3 9.4 2.6 7.9 0.7 2.3 2 0 0 2 2 2 0 Stringent starvation protein B Collagen PF01391.18 EKX39803.1 - 1.4e-13 50.4 62.9 2.6e-08 33.5 30.4 2.1 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) SRCR PF00530.18 EKX39803.1 - 2.3e-11 44.1 0.1 6.4e-11 42.6 0.1 1.7 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 EKX39803.1 - 3.3e-06 27.5 0.1 1.6e-05 25.4 0.1 2.2 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain Hepsin-SRCR PF09272.10 EKX39803.1 - 0.018 15.5 0.2 0.061 13.8 0.2 1.9 2 0 0 2 2 2 0 Hepsin, SRCR domain LRR_6 PF13516.6 EKX39805.1 - 5.5e-37 122.7 37.5 1e-05 25.2 0.0 12.1 12 0 0 12 12 12 9 Leucine Rich repeat LRR_4 PF12799.7 EKX39805.1 - 1e-08 35.3 16.6 0.11 12.9 0.5 7.0 6 2 2 8 8 8 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX39805.1 - 0.00011 22.2 12.0 8.1 7.4 0.1 8.8 9 2 0 9 9 9 1 Leucine Rich Repeat FeS PF04060.13 EKX39805.1 - 0.00064 19.3 5.8 0.24 11.1 3.5 2.5 2 0 0 2 2 2 2 Putative Fe-S cluster LRR_8 PF13855.6 EKX39805.1 - 0.04 13.7 26.6 6 6.7 0.4 7.9 3 3 2 5 5 5 0 Leucine rich repeat Cyt-b5 PF00173.28 EKX39807.1 - 1.5e-22 79.5 0.1 2e-22 79.1 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MMR_HSR1 PF01926.23 EKX39808.1 - 9.6e-16 57.9 0.0 4.2e-14 52.6 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EKX39808.1 - 1.1e-05 25.1 0.0 0.00044 19.8 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EKX39808.1 - 0.00016 21.6 0.4 0.036 14.0 0.2 2.5 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 EKX39808.1 - 0.031 13.6 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 AIG1 family cobW PF02492.19 EKX39808.1 - 0.064 12.8 0.0 0.46 10.1 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 EKX39808.1 - 0.18 11.8 0.2 0.18 11.8 0.2 2.1 2 1 0 2 2 2 0 Dynamin family SET PF00856.28 EKX39809.1 - 6.5e-11 42.9 0.0 1.9e-10 41.4 0.0 1.8 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 EKX39809.1 - 0.0058 17.3 0.6 1.2 9.8 0.0 2.9 3 0 0 3 3 3 2 Rubisco LSMT substrate-binding DUF5428 PF17493.2 EKX39809.1 - 0.079 13.4 0.0 0.33 11.4 0.0 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5428) SAM_2 PF07647.17 EKX39810.1 - 1.3e-08 34.9 0.0 3.6e-08 33.4 0.1 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EKX39810.1 - 3.2e-06 27.5 0.0 7.2e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4265 PF14085.6 EKX39810.1 - 0.13 12.3 0.0 0.33 10.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) Mito_carr PF00153.27 EKX39811.1 - 8.3e-42 141.0 6.3 6.1e-18 64.5 0.7 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein SET PF00856.28 EKX39812.1 - 8.3e-10 39.3 0.0 4.2e-09 37.0 0.0 2.0 1 1 0 2 2 2 1 SET domain zf-4CXXC_R1 PF10497.9 EKX39813.1 - 0.00014 22.0 12.1 0.00026 21.2 12.1 1.4 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_2 PF13639.6 EKX39813.1 - 0.099 13.0 13.8 0.22 11.9 13.8 1.6 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.8 EKX39813.1 - 0.88 9.8 10.3 2.2 8.5 10.3 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain MIP PF00230.20 EKX39814.1 - 1.5e-42 145.9 12.1 1.9e-42 145.5 12.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF5518 PF17647.1 EKX39814.1 - 0.014 15.5 4.6 0.014 15.5 4.6 3.2 2 1 0 2 2 2 0 Family of unknown function (DUF5518) MerC PF03203.14 EKX39814.1 - 5.1 7.6 8.6 0.97 9.9 4.1 2.0 1 1 1 2 2 2 0 MerC mercury resistance protein RIB43A PF05914.12 EKX39819.1 - 6.4e-96 321.4 58.8 7.1e-96 321.2 58.8 1.0 1 0 0 1 1 1 1 RIB43A FIST_C PF10442.9 EKX39819.1 - 0.087 12.8 3.6 3.3 7.7 0.4 2.4 2 0 0 2 2 2 0 FIST C domain LRR_6 PF13516.6 EKX39821.1 - 3e-12 45.6 1.2 0.001 18.9 0.0 4.5 4 0 0 4 4 4 3 Leucine Rich repeat EF-hand_5 PF13202.6 EKX39822.1 - 0.00017 21.0 0.1 0.00029 20.2 0.1 1.3 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 EKX39822.1 - 0.00017 20.9 0.1 0.00027 20.3 0.1 1.4 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EKX39822.1 - 0.0041 17.0 0.0 0.0071 16.2 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 EKX39822.1 - 0.016 15.0 0.1 0.028 14.2 0.1 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_7 PF13499.6 EKX39822.1 - 0.036 14.5 0.1 0.076 13.5 0.1 1.4 1 1 0 1 1 1 0 EF-hand domain pair Pkinase PF00069.25 EKX39824.1 - 1.2e-13 51.0 0.0 1.8e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EKX39824.1 - 0.0025 16.6 0.0 0.0032 16.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX39824.1 - 0.0031 17.5 0.0 0.0056 16.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX39824.1 - 0.0043 16.4 0.0 0.0068 15.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EKX39824.1 - 0.021 14.5 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 E3_UbLigase_R4 PF13764.6 EKX39826.1 - 5e-207 689.8 0.0 1.9e-206 687.9 0.0 2.0 2 0 0 2 2 2 1 E3 ubiquitin-protein ligase UBR4 ZZ PF00569.17 EKX39826.1 - 3.8e-11 42.6 7.8 3.8e-11 42.6 7.8 3.4 2 0 0 2 2 2 1 Zinc finger, ZZ type Cnn_1N PF07989.11 EKX39826.1 - 0.023 14.8 2.2 0.097 12.8 2.2 2.2 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Cnd1 PF12717.7 EKX39826.1 - 0.027 14.5 0.1 0.027 14.5 0.1 4.5 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EKX39826.1 - 0.14 12.6 1.1 3.8 8.0 0.1 4.1 4 0 0 4 4 4 0 HEAT repeats V-ATPase_G_2 PF16999.5 EKX39826.1 - 4.8 7.7 8.5 15 6.1 8.5 1.8 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DRMBL PF07522.14 EKX39827.1 - 1e-20 73.9 0.0 1.7e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EKX39827.1 - 0.00048 19.7 0.1 0.001 18.7 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EKX39827.1 - 0.11 12.6 5.8 0.45 10.5 5.8 2.1 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily RelA_SpoT PF04607.17 EKX39829.1 - 0.0082 16.4 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins Methyltransf_31 PF13847.6 EKX39830.1 - 2.9e-18 66.1 0.0 4e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX39830.1 - 7.8e-15 55.4 0.0 1.3e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX39830.1 - 1.2e-13 51.2 0.0 1.4e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX39830.1 - 1.2e-13 51.5 0.0 2.3e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX39830.1 - 4.2e-13 49.7 0.0 7.5e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX39830.1 - 5.9e-07 29.0 0.0 8.1e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EKX39830.1 - 3.2e-05 23.6 0.0 4.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 EKX39830.1 - 0.00021 20.9 0.0 0.00032 20.4 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 EKX39830.1 - 0.011 15.7 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 EKX39830.1 - 0.12 11.6 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RCC1 PF00415.18 EKX39831.1 - 8.1e-260 839.6 62.2 7e-14 52.2 0.2 27.4 28 0 0 28 28 28 25 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX39831.1 - 4.6e-102 332.2 133.3 2.3e-06 27.2 1.3 26.5 27 0 0 27 27 27 22 Regulator of chromosome condensation (RCC1) repeat SAM_1 PF00536.30 EKX39831.1 - 0.00045 20.6 0.0 0.0021 18.5 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) MIP PF00230.20 EKX39832.1 - 1.9e-45 155.4 17.5 2.4e-45 155.0 17.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein Tubulin_2 PF13809.6 EKX39832.1 - 0.26 10.5 0.2 0.35 10.0 0.2 1.1 1 0 0 1 1 1 0 Tubulin like DUF805 PF05656.14 EKX39832.1 - 2.8 8.4 7.8 4.4 7.8 3.8 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF805) DUF423 PF04241.15 EKX39833.1 - 1.8e-27 95.3 4.7 6.5e-27 93.6 4.7 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF423) WD40 PF00400.32 EKX39834.1 - 1.2e-07 32.2 15.1 0.014 16.3 0.2 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Myb_DNA-bind_5 PF13873.6 EKX39834.1 - 0.01 15.9 3.2 0.015 15.3 0.8 2.6 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Ge1_WD40 PF16529.5 EKX39834.1 - 0.013 14.5 0.1 0.035 13.1 0.1 1.7 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein KNOX2 PF03791.13 EKX39834.1 - 0.15 11.5 0.7 0.43 10.1 0.7 1.7 1 0 0 1 1 1 0 KNOX2 domain Beta_helix PF13229.6 EKX39835.1 - 1e-63 213.9 34.8 7.4e-22 77.9 11.9 5.2 2 2 3 5 5 5 5 Right handed beta helix region NosD PF05048.13 EKX39835.1 - 7.7e-40 136.7 16.4 7.7e-11 41.7 1.3 5.2 1 1 3 5 5 5 5 Periplasmic copper-binding protein (NosD) PDZ PF00595.24 EKX39837.1 - 4.4e-11 43.0 0.0 7.4e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX39837.1 - 1.3e-07 31.3 0.2 2.6e-07 30.4 0.2 1.5 1 0 0 1 1 1 1 PDZ domain Sfi1 PF08457.10 EKX39837.1 - 8.3e-06 24.6 2.7 8.3e-06 24.6 2.7 2.1 1 1 1 2 2 2 2 Sfi1 spindle body protein PDZ_2 PF13180.6 EKX39837.1 - 0.0042 17.4 0.0 0.0095 16.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain FtsK_gamma PF09397.10 EKX39839.1 - 0.28 11.0 32.1 26 4.7 0.9 8.1 1 1 8 9 9 9 0 Ftsk gamma domain Ion_trans PF00520.31 EKX39840.1 - 1.2e-29 103.2 6.9 1.4e-29 103.0 6.9 1.0 1 0 0 1 1 1 1 Ion transport protein BBS2_Mid PF14783.6 EKX39841.1 - 0.12 12.4 0.1 0.26 11.3 0.1 1.5 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region Methyltransf_14 PF08484.11 EKX39841.1 - 2.9 7.7 7.6 0.32 10.8 2.4 2.2 2 1 0 2 2 2 0 C-methyltransferase C-terminal domain zf-RING_2 PF13639.6 EKX39842.1 - 6.2e-12 45.7 3.9 6.2e-12 45.7 3.9 1.9 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EKX39842.1 - 7.1e-09 35.8 3.6 1.5e-08 34.8 3.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EKX39842.1 - 1.9e-08 34.0 3.7 3.6e-08 33.1 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EKX39842.1 - 2.5e-08 33.5 2.1 2.5e-08 33.5 2.1 2.0 3 0 0 3 3 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 EKX39842.1 - 5.5e-08 32.6 2.8 1.1e-07 31.6 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX39842.1 - 4.3e-06 26.5 3.3 8.9e-06 25.5 3.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EKX39842.1 - 5.3e-06 26.4 1.1 9.7e-06 25.6 1.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EKX39842.1 - 7.1e-06 25.9 2.1 1.3e-05 25.0 2.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EKX39842.1 - 8e-06 25.6 1.8 8e-06 25.6 1.8 1.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX39842.1 - 1.3e-05 25.1 0.2 2.6e-05 24.2 0.1 1.6 1 1 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 EKX39842.1 - 1.6e-05 24.5 4.3 3.1e-05 23.5 4.3 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 EKX39842.1 - 0.00011 22.3 0.4 0.00026 21.1 0.4 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 EKX39842.1 - 0.00029 20.9 5.2 0.0075 16.4 5.4 2.4 1 1 1 2 2 2 1 FANCL C-terminal domain RINGv PF12906.7 EKX39842.1 - 0.00033 20.7 3.7 0.001 19.2 3.7 1.9 1 1 0 1 1 1 1 RING-variant domain zf-RING-like PF08746.11 EKX39842.1 - 0.00072 19.8 3.3 0.0013 19.0 3.3 1.4 1 0 0 1 1 1 1 RING-like domain zf-Nse PF11789.8 EKX39842.1 - 0.0064 16.3 0.1 0.01 15.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF3431 PF11913.8 EKX39842.1 - 0.017 14.9 0.9 0.02 14.7 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3431) PHD PF00628.29 EKX39842.1 - 0.021 14.7 3.5 0.039 13.9 3.5 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_10 PF16685.5 EKX39842.1 - 0.024 14.8 2.2 0.042 14.0 2.2 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-HC5HC2H_2 PF13832.6 EKX39842.1 - 0.041 14.0 2.0 0.041 14.0 2.0 2.2 1 1 1 2 2 2 0 PHD-zinc-finger like domain Prok-RING_1 PF14446.6 EKX39842.1 - 0.06 13.3 1.1 0.57 10.1 0.2 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.6 EKX39842.1 - 0.46 10.8 7.2 0.13 12.6 1.4 2.4 1 1 1 2 2 2 0 PHD-like zinc-binding domain DUF4116 PF13475.6 EKX39843.1 - 4.3e-271 874.8 0.0 3.5e-16 58.7 0.0 20.8 12 4 11 24 24 24 24 Domain of unknown function (DUF4116) Rsbr_N PF08678.10 EKX39843.1 - 1.2e-08 35.1 0.7 2.6 8.1 0.0 9.1 4 3 5 10 10 10 1 Rsbr N terminal CPT_N PF16484.5 EKX39843.1 - 1.2e-08 34.8 0.5 11 6.1 0.0 10.8 13 1 1 14 14 14 1 Carnitine O-palmitoyltransferase N-terminus DUF1667 PF07892.11 EKX39843.1 - 2.2e-07 30.9 1.0 36 4.5 0.0 9.6 6 4 4 11 11 11 0 Protein of unknown function (DUF1667) PhaC_N PF07167.13 EKX39843.1 - 0.0013 18.4 2.0 0.068 12.8 0.0 4.3 5 1 0 6 6 6 1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus DUF2688 PF10892.8 EKX39843.1 - 0.0033 16.9 0.0 3.9 7.0 0.0 5.2 6 0 0 6 6 6 1 Protein of unknown function (DUF2688) DUF2971 PF11185.8 EKX39843.1 - 0.024 15.8 0.1 38 5.5 0.0 5.5 5 1 1 6 6 6 0 Protein of unknown function (DUF2971) DUF4145 PF13643.6 EKX39843.1 - 0.12 12.6 1.5 8.1 6.7 0.1 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4145) S_layer_C PF05124.12 EKX39843.1 - 0.27 11.2 4.9 9.4 6.2 0.1 5.0 4 1 1 6 6 6 0 S-layer like family, C-terminal region DUF2853 PF11015.8 EKX39843.1 - 0.32 11.7 3.5 1.8 9.3 0.1 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2853) UBA PF00627.31 EKX39843.1 - 1.5 8.8 4.6 22 5.1 0.1 5.2 5 0 0 5 5 5 0 UBA/TS-N domain DUF2150 PF09920.9 EKX39843.1 - 3.3 7.7 33.1 4.3 7.3 0.2 8.3 4 3 2 9 9 9 0 Uncharacterized protein conserved in archaea (DUF2150) PDZ_6 PF17820.1 EKX39849.1 - 0.00098 18.9 0.1 0.0029 17.4 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX39849.1 - 0.0073 16.6 0.0 0.02 15.2 0.0 1.7 1 0 0 1 1 1 1 PDZ domain ECD PF18432.1 EKX39849.1 - 0.07 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Extracellular Cadherin domain DUF3131 PF11329.8 EKX39849.1 - 0.089 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3131) DUF3740 PF12548.8 EKX39849.1 - 0.14 12.6 0.6 0.52 10.7 0.0 2.0 2 0 0 2 2 2 0 Sulfatase protein Spectrin_like PF18373.1 EKX39849.1 - 0.92 9.6 4.5 0.6 10.2 2.2 1.9 2 0 0 2 2 2 0 Spectrin like domain Methyltransf_23 PF13489.6 EKX39850.1 - 0.00034 20.5 0.0 0.00059 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TIG PF01833.24 EKX39852.1 - 1.1e-17 63.8 15.6 2.6e-06 27.4 0.8 10.2 10 0 0 10 10 10 5 IPT/TIG domain Laminin_G_3 PF13385.6 EKX39852.1 - 2.3e-13 50.6 0.0 1.5e-12 47.9 0.0 2.5 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EPTP PF03736.17 EKX39852.1 - 3.7e-08 33.2 2.5 0.0014 18.6 0.0 5.4 5 0 0 5 5 5 2 EPTP domain Lactonase PF10282.9 EKX39852.1 - 0.0065 15.8 0.2 4.9 6.3 0.0 3.8 4 0 0 4 4 4 1 Lactonase, 7-bladed beta-propeller Big_9 PF17963.1 EKX39852.1 - 1.3 9.8 35.5 4.6 8.1 0.0 14.2 16 2 0 16 16 16 0 Bacterial Ig domain GIT1_C PF12205.8 EKX39854.1 - 0.025 14.7 0.6 0.025 14.7 0.6 2.8 4 0 0 4 4 4 0 G protein-coupled receptor kinase-interacting protein 1 C term OmpH PF03938.14 EKX39854.1 - 0.08 13.3 14.5 0.7 10.2 1.9 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF1759 PF03564.15 EKX39854.1 - 0.19 11.6 1.6 2.3 8.1 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) GAS PF13851.6 EKX39854.1 - 0.86 8.9 22.6 0.63 9.3 6.4 3.4 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding Fmp27_WPPW PF10359.9 EKX39854.1 - 2.5 6.9 10.4 3.9 6.2 1.1 2.2 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF948 PF06103.11 EKX39854.1 - 2.7 8.3 6.6 12 6.2 0.4 3.5 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Serine_rich PF08824.10 EKX39854.1 - 3.2 7.7 13.3 2 8.4 0.6 4.5 1 1 3 5 5 5 0 Serine rich protein interaction domain FapA PF03961.13 EKX39854.1 - 3.6 6.1 8.1 7.3 5.1 2.6 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 EKX39854.1 - 4.5 5.1 9.0 3.3 5.5 2.2 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF2203 PF09969.9 EKX39854.1 - 6.7 7.5 15.4 1.2 9.9 1.9 3.5 2 2 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) ZapB PF06005.12 EKX39854.1 - 8.1 7.0 26.1 4.2 7.9 1.1 4.7 4 1 0 4 4 3 0 Cell division protein ZapB Cdh1_DBD_1 PF18196.1 EKX39854.1 - 8.5 6.7 10.0 0.63 10.4 1.0 2.5 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 Phage_GP20 PF06810.11 EKX39854.1 - 8.9 6.1 14.0 3.5 7.4 1.6 2.8 2 1 0 2 2 2 0 Phage minor structural protein GP20 SUI1 PF01253.22 EKX39855.1 - 2.9e-19 69.4 0.4 4.8e-19 68.7 0.4 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 Imm3 PF14425.6 EKX39855.1 - 0.06 13.4 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Immunity protein Imm3 Pkinase PF00069.25 EKX39856.1 - 1.2e-54 185.5 0.0 1.4e-54 185.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX39856.1 - 9.2e-30 103.8 0.0 1.1e-27 96.9 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX39856.1 - 1.3e-05 24.7 0.0 0.00076 18.9 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EKX39856.1 - 1.4e-05 24.3 0.1 1.9e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EKX39856.1 - 0.0024 17.3 0.0 0.005 16.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EKX39856.1 - 0.013 15.1 0.0 1.5 8.4 0.0 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EKX39856.1 - 0.064 13.2 0.0 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX39856.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 EKX39857.1 - 3.2e-58 197.2 0.0 4.3e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX39857.1 - 1.1e-40 139.6 0.0 1.7e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX39857.1 - 2.8e-05 23.6 0.0 7.5e-05 22.2 0.0 1.7 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EKX39857.1 - 0.055 12.2 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase YgbB PF02542.16 EKX39858.1 - 2e-60 203.6 0.0 2.3e-60 203.4 0.0 1.0 1 0 0 1 1 1 1 YgbB family KcnmB2_inactiv PF09303.10 EKX39858.1 - 2 8.3 3.4 3.8 7.4 3.4 1.4 1 0 0 1 1 1 0 KCNMB2, ball and chain domain Acetyltransf_7 PF13508.7 EKX39859.1 - 0.00011 22.6 0.0 0.00014 22.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EKX39859.1 - 0.032 14.4 0.0 0.038 14.2 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Phyto_Pns9_10 PF05878.11 EKX39860.1 - 0.06 12.5 0.0 0.071 12.2 0.0 1.0 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 DUF2961 PF11175.8 EKX39861.1 - 0.052 13.2 0.0 0.066 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) Gemini_BL1 PF00845.19 EKX39862.1 - 0.0046 16.6 0.2 0.21 11.1 0.1 2.0 1 1 1 2 2 2 2 Geminivirus BL1 movement protein Toxin_5 PF05294.13 EKX39862.1 - 0.026 14.9 5.3 0.29 11.6 1.0 2.3 2 0 0 2 2 2 0 Scorpion short toxin PAN_2 PF08276.11 EKX39862.1 - 0.041 14.0 0.8 2 8.6 0.2 2.3 2 0 0 2 2 2 0 PAN-like domain HrpB7 PF09486.10 EKX39862.1 - 3.7 7.9 5.9 3.7 7.9 1.0 2.1 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Ephrin_rec_like PF07699.13 EKX39863.1 - 6.9e-12 44.9 125.5 4.6e-06 26.3 5.5 14.2 9 4 4 13 13 13 8 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX39863.1 - 0.006 17.0 5.0 0.006 17.0 5.0 15.6 11 5 7 19 19 19 6 TNFR/NGFR cysteine-rich region BioT2 PF15368.6 EKX39864.1 - 0.0027 17.7 0.0 0.0068 16.4 0.0 1.6 1 0 0 1 1 1 1 Spermatogenesis family BioT2 SAM_KSR1 PF13543.6 EKX39864.1 - 0.064 13.4 0.4 0.51 10.5 0.1 2.5 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 ANAPC4 PF12896.7 EKX39864.1 - 0.091 12.2 0.9 19 4.7 0.2 3.6 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 4 ArAE_1_C PF11728.8 EKX39865.1 - 0.12 12.3 0.9 0.32 11.0 0.1 2.0 2 0 0 2 2 2 0 Putative aromatic acid exporter C-terminal domain zf-C3HC4_3 PF13920.6 EKX39866.1 - 0.0079 16.0 16.4 0.017 15.0 16.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF4694 PF15765.5 EKX39867.1 - 0.0037 17.3 4.7 0.0074 16.3 4.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4694) SR-25 PF10500.9 EKX39867.1 - 0.055 13.1 10.0 0.097 12.3 10.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Auxin_repressed PF05564.12 EKX39867.1 - 0.15 12.8 2.0 0.15 12.8 0.4 1.8 2 0 0 2 2 2 0 Dormancy/auxin associated protein CDC45 PF02724.14 EKX39867.1 - 0.34 9.2 3.0 0.45 8.7 3.0 1.1 1 0 0 1 1 1 0 CDC45-like protein GET2 PF08690.10 EKX39867.1 - 0.38 10.4 2.2 0.56 9.8 2.2 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 XRCC4 PF06632.12 EKX39867.1 - 0.68 8.7 4.6 1 8.1 4.6 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 AF-4 PF05110.13 EKX39867.1 - 2.1 6.3 12.0 2.8 5.9 12.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF4614 PF15391.6 EKX39867.1 - 2.3 8.2 8.6 3.8 7.5 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Apt1 PF10351.9 EKX39867.1 - 6.2 5.6 9.1 9.5 4.9 9.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Patched PF02460.18 EKX39868.1 - 2e-17 62.6 27.6 1.7e-10 39.7 5.2 2.3 2 0 0 2 2 2 2 Patched family MMPL PF03176.15 EKX39868.1 - 4e-10 39.1 11.6 4e-10 39.1 11.6 2.7 2 1 0 2 2 2 1 MMPL family Sterol-sensing PF12349.8 EKX39868.1 - 1e-06 28.6 10.6 1e-06 28.6 10.6 2.7 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation SecD_SecF PF02355.16 EKX39868.1 - 0.2 11.1 32.7 0.015 14.7 12.3 2.4 2 0 0 2 2 2 0 Protein export membrane protein Filamin PF00630.19 EKX39869.1 - 1.1e-32 112.8 0.1 8.7e-16 58.6 0.0 2.1 1 1 1 2 2 2 2 Filamin/ABP280 repeat Invasin_D3 PF09134.10 EKX39869.1 - 5.3e-12 45.9 8.1 3.8e-06 27.1 1.8 2.5 2 1 0 2 2 2 2 Invasin, domain 3 Cadherin_5 PF17892.1 EKX39869.1 - 4.8e-06 26.5 2.2 0.01 15.8 0.1 2.4 2 1 0 2 2 2 2 Cadherin-like domain Big_1 PF02369.16 EKX39869.1 - 1.6e-05 24.8 8.4 0.042 13.9 0.5 3.1 2 1 0 2 2 2 2 Bacterial Ig-like domain (group 1) Neurexophilin PF06312.12 EKX39869.1 - 0.00017 21.1 2.0 0.086 12.3 0.1 2.1 2 0 0 2 2 2 2 Neurexophilin DUF5011 PF16403.5 EKX39869.1 - 0.0017 18.5 3.7 0.13 12.4 0.2 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF5011) Y_Y_Y PF07495.13 EKX39869.1 - 0.0039 17.1 0.2 1.4 8.9 0.0 2.5 2 0 0 2 2 2 2 Y_Y_Y domain YtkA PF13115.6 EKX39869.1 - 0.031 14.9 0.4 11 6.7 0.0 2.6 2 0 0 2 2 2 0 YtkA-like RunxI PF08504.11 EKX39869.1 - 0.072 13.8 2.4 6.4 7.5 0.2 2.5 2 0 0 2 2 2 0 Runx inhibition domain Lipoprotein_17 PF04200.12 EKX39869.1 - 0.25 11.7 0.9 6.1 7.3 0.1 2.3 2 0 0 2 2 2 0 Lipoprotein associated domain Big_3_5 PF16640.5 EKX39869.1 - 0.55 10.4 13.7 3.4 7.9 3.1 2.7 1 1 0 2 2 2 0 Bacterial Ig-like domain (group 3) DUF1541 PF07563.11 EKX39869.1 - 2.8 7.9 5.0 17 5.4 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1541) RNB PF00773.19 EKX39870.1 - 2.4e-59 201.3 0.0 6.5e-58 196.6 0.0 2.3 1 1 0 1 1 1 1 RNB domain zf-C2H2_2 PF12756.7 EKX39871.1 - 2.8e-07 30.8 0.2 0.021 15.2 0.0 3.2 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 EKX39871.1 - 1.7e-06 28.2 3.3 0.44 10.9 0.3 3.5 3 0 0 3 3 3 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 EKX39871.1 - 5.3e-06 26.2 0.9 0.92 9.4 0.1 3.5 3 0 0 3 3 3 2 C2H2 type zinc-finger (1 copy) zf-C2H2_4 PF13894.6 EKX39871.1 - 0.0001 22.8 19.3 0.0087 16.8 0.7 4.2 4 1 0 4 4 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EKX39871.1 - 0.012 16.0 15.0 0.042 14.3 1.3 4.0 3 1 0 3 3 3 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 EKX39871.1 - 0.023 15.3 0.6 1.2 9.8 0.0 2.8 3 0 0 3 3 2 0 FOXP coiled-coil domain zf_UBZ PF18439.1 EKX39871.1 - 0.033 13.8 2.5 0.56 9.8 0.1 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 EKX39871.1 - 0.053 13.6 6.6 1.9 8.7 0.1 2.9 3 0 0 3 3 3 0 Zinc ribbon domain zf-C2H2_6 PF13912.6 EKX39871.1 - 0.054 13.5 0.8 0.054 13.5 0.8 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EKX39871.1 - 0.067 13.7 11.5 3.7 8.1 0.2 4.2 4 0 0 4 4 3 0 Zinc-finger double domain OrsD PF12013.8 EKX39871.1 - 0.08 13.4 0.9 25 5.4 1.0 3.3 2 1 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Ogr_Delta PF04606.12 EKX39871.1 - 0.13 12.3 4.2 3.9 7.5 0.1 3.2 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger DUF2256 PF10013.9 EKX39871.1 - 0.19 11.9 6.8 27 5.0 0.7 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn_Tnp_IS1595 PF12760.7 EKX39871.1 - 0.19 11.8 7.0 4 7.5 0.1 3.4 3 0 0 3 3 3 0 Transposase zinc-ribbon domain TRAF6_Z2 PF18048.1 EKX39871.1 - 0.21 11.7 1.3 5.9 7.1 0.1 2.6 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-RING_7 PF02591.15 EKX39871.1 - 1.9 8.7 4.8 28 5.0 0.1 2.7 2 0 0 2 2 2 0 C4-type zinc ribbon domain zf-C2H2_jaz PF12171.8 EKX39871.1 - 2.7 8.4 9.9 0.24 11.7 0.5 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 EKX39871.1 - 4.5 7.3 18.8 0.051 13.5 2.0 3.0 3 0 0 3 3 2 0 zinc-finger of a C2HC-type PP2C PF00481.21 EKX39872.1 - 1.8e-40 139.2 0.0 2.4e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EKX39872.1 - 1.8e-06 27.7 0.1 5.9e-06 26.1 0.1 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C DUF2092 PF09865.9 EKX39872.1 - 0.067 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2092) DUF1024 PF06260.12 EKX39873.1 - 0.16 12.3 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1024) RRM_1 PF00076.22 EKX39874.1 - 1.1e-33 114.9 0.0 1.3e-16 60.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EKX39874.1 - 1.2e-09 38.1 0.0 2.1e-05 24.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EKX39874.1 - 3.4e-05 23.8 0.0 0.38 10.8 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EKX39874.1 - 0.0079 16.2 0.1 1.7 8.8 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif DUF1866 PF08952.11 EKX39874.1 - 0.11 12.3 0.0 15 5.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) Keratin_2_head PF16208.5 EKX39874.1 - 1.4 9.0 31.1 2.3 8.3 31.1 1.4 1 0 0 1 1 1 0 Keratin type II head DUF2070 PF09843.9 EKX39875.1 - 7.7 4.7 12.9 13 3.9 12.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Beta_helix PF13229.6 EKX39876.1 - 3.5e-44 150.4 30.9 4.4e-18 65.6 3.4 4.4 1 1 3 4 4 4 4 Right handed beta helix region NosD PF05048.13 EKX39876.1 - 8.9e-36 123.4 17.1 1.9e-11 43.7 0.3 4.4 1 1 3 4 4 4 4 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.11 EKX39876.1 - 1.6e-10 40.8 21.6 0.052 12.9 0.0 5.4 1 1 3 5 5 5 5 Protein of unknown function (DUF1565) Ank_2 PF12796.7 EKX39877.1 - 1.2e-14 54.7 0.0 1.3e-14 54.5 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX39877.1 - 4e-14 52.8 0.0 1.6e-08 34.9 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX39877.1 - 3.6e-12 46.2 0.1 2.8e-05 24.3 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EKX39877.1 - 3.3e-11 42.4 0.1 7.8e-05 22.8 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EKX39877.1 - 5.3e-10 39.4 0.0 9e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX39878.1 - 1.3e-15 57.0 0.6 1.2e-06 28.7 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 EKX39878.1 - 2.6e-15 56.8 0.2 2.3e-06 28.1 0.0 2.7 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX39878.1 - 2.4e-14 53.5 0.5 3.8e-05 24.2 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX39878.1 - 1.2e-13 49.9 0.9 1.2e-05 25.3 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EKX39878.1 - 5.9e-13 48.8 0.5 3.7e-05 23.9 0.1 2.6 2 1 0 2 2 2 2 Ankyrin repeats (many copies) DUF3292 PF11696.8 EKX39879.1 - 0.018 13.5 0.9 0.024 13.0 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) zf-C2H2_9 PF16293.5 EKX39879.1 - 0.018 14.9 0.2 0.073 12.9 0.0 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_6 PF13912.6 EKX39879.1 - 0.026 14.5 0.1 0.042 13.9 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EKX39879.1 - 0.027 14.9 1.0 0.063 13.8 1.0 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EKX39879.1 - 0.037 14.9 0.5 0.037 14.9 0.5 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger RNA_POL_M_15KD PF02150.16 EKX39879.1 - 0.061 13.2 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit zf-C2H2_2 PF12756.7 EKX39879.1 - 0.096 13.0 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) EF-hand_5 PF13202.6 EKX39881.1 - 3.8e-15 54.6 1.5 1.3e-07 30.8 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX39881.1 - 2.7e-13 50.1 7.1 2.6e-11 43.8 1.9 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX39881.1 - 9.2e-12 43.6 3.5 6.4e-06 25.3 0.4 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EKX39881.1 - 1.7e-10 39.9 1.1 0.0006 19.5 0.1 3.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 EKX39881.1 - 7.1e-09 35.4 2.2 5.6e-06 26.1 0.5 2.7 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX39881.1 - 5.9e-07 29.8 0.2 2.4e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region TIR_2 PF13676.6 EKX39881.1 - 1.3e-05 25.8 0.0 2.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 TIR domain Dockerin_1 PF00404.18 EKX39881.1 - 0.03 14.5 0.0 7 6.9 0.0 2.3 2 0 0 2 2 2 0 Dockerin type I domain TIR PF01582.20 EKX39881.1 - 0.17 11.7 0.1 0.21 11.4 0.1 1.3 1 1 0 1 1 1 0 TIR domain F-box PF00646.33 EKX39891.1 - 0.0004 20.2 0.3 0.001 18.9 0.3 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EKX39891.1 - 0.011 15.6 0.6 0.03 14.2 0.6 1.8 1 1 0 1 1 1 0 F-box-like 2OG-FeII_Oxy_3 PF13640.6 EKX39892.1 - 9.4e-18 64.9 0.0 1.5e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 EKX39892.1 - 1.8e-07 31.7 0.0 3.3e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ion_trans PF00520.31 EKX39893.1 - 5.9e-33 114.1 26.8 8.2e-33 113.6 26.8 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EKX39893.1 - 2.1e-06 26.7 23.6 2.4e-05 23.2 10.8 2.3 2 0 0 2 2 2 2 Polycystin cation channel EF-hand_7 PF13499.6 EKX39893.1 - 0.069 13.6 0.2 0.29 11.6 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair CheF-arch PF04283.12 EKX39893.1 - 0.14 11.9 0.0 0.42 10.3 0.0 1.7 2 0 0 2 2 2 0 Chemotaxis signal transduction system protein F from archaea Pox_A14 PF05767.12 EKX39893.1 - 5.1 7.3 11.6 10 6.3 1.0 3.3 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 zf-GRF PF06839.12 EKX39895.1 - 0.0021 18.1 26.9 2.4 8.3 0.5 6.9 1 1 5 6 6 6 4 GRF zinc finger DUF2839 PF10999.8 EKX39895.1 - 1.4 9.3 7.7 3 8.3 0.8 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2839) Sorb PF02208.16 EKX39895.1 - 5.8 6.9 48.1 2.9 7.8 1.3 7.6 2 2 7 9 9 9 0 Sorbin homologous domain DUF883 PF05957.13 EKX39895.1 - 9.5 6.9 6.1 10 6.8 0.6 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF1640 PF07798.11 EKX39896.1 - 0.024 14.7 21.6 0.025 14.6 13.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Gln-synt_C PF00120.24 EKX39896.1 - 0.15 11.1 9.7 0.92 8.4 1.8 2.4 1 1 1 2 2 2 0 Glutamine synthetase, catalytic domain Prominin PF05478.11 EKX39896.1 - 0.36 8.7 7.2 0.48 8.3 7.2 1.1 1 0 0 1 1 1 0 Prominin Atg14 PF10186.9 EKX39896.1 - 2.3 7.2 8.3 4.4 6.3 8.3 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MAJIN PF15077.6 EKX39896.1 - 7.1 6.4 8.3 9.8 5.9 8.3 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein vATP-synt_AC39 PF01992.16 EKX39898.1 - 2.1e-110 369.4 5.0 2.3e-110 369.2 5.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Peptidase_M13 PF01431.21 EKX39899.1 - 6.7e-60 202.2 0.8 6.7e-60 202.2 0.8 1.7 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13_N PF05649.13 EKX39899.1 - 2.1e-59 202.1 1.5 2.9e-59 201.7 1.5 1.2 1 0 0 1 1 1 1 Peptidase family M13 N6_Mtase PF02384.16 EKX39900.1 - 0.01 15.1 0.1 0.02 14.1 0.1 1.5 1 0 0 1 1 1 0 N-6 DNA Methylase MTS PF05175.14 EKX39900.1 - 0.023 14.3 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain N6-adenineMlase PF10237.9 EKX39900.1 - 0.029 14.2 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase EcoRI_methylase PF13651.6 EKX39900.1 - 0.033 13.4 0.0 0.07 12.3 0.0 1.5 1 0 0 1 1 1 0 Adenine-specific methyltransferase EcoRI Cons_hypoth95 PF03602.15 EKX39900.1 - 0.049 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Macoilin PF09726.9 EKX39900.1 - 0.26 9.8 5.5 0.27 9.7 5.5 1.1 1 0 0 1 1 1 0 Macoilin family DUF4551 PF15087.6 EKX39900.1 - 7.5 5.2 9.2 10 4.8 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF5388 PF17363.2 EKX39903.1 - 0.19 11.9 0.0 11 6.3 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5388) C2 PF00168.30 EKX39904.1 - 1.8e-14 53.9 0.0 3.5e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain XPA_C PF05181.12 EKX39905.1 - 6e-21 74.2 0.2 7.3e-21 73.9 0.2 1.1 1 0 0 1 1 1 1 XPA protein C-terminus Cupin_4 PF08007.12 EKX39906.1 - 9.8e-32 110.7 0.2 2.8e-31 109.2 0.2 1.6 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 EKX39906.1 - 4.1e-07 30.0 0.1 7.4e-05 22.6 0.1 2.3 1 1 0 1 1 1 1 Cupin-like domain Cupin_1 PF00190.22 EKX39906.1 - 0.019 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Cupin Peptidase_M50 PF02163.22 EKX39907.1 - 5.8e-61 205.9 0.1 7.1e-61 205.6 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M50 PDZ PF00595.24 EKX39907.1 - 8.7e-08 32.4 0.7 3.7e-07 30.4 0.4 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EKX39907.1 - 1.6e-07 31.1 0.1 4e-07 29.8 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX39907.1 - 3.6e-07 30.4 0.2 8.1e-07 29.3 0.2 1.5 1 0 0 1 1 1 1 PDZ domain Importin_rep_4 PF18808.1 EKX39908.1 - 4.3e-25 87.8 19.3 3e-23 81.9 0.9 6.3 6 0 0 6 6 6 2 Importin repeat HEAT_2 PF13646.6 EKX39908.1 - 9.4e-22 77.2 2.7 8.2e-08 32.5 0.1 8.0 6 2 2 8 8 8 4 HEAT repeats HEAT_EZ PF13513.6 EKX39908.1 - 1.2e-21 76.7 17.4 3.9e-05 24.1 0.0 11.4 9 3 3 12 12 11 4 HEAT-like repeat HEAT PF02985.22 EKX39908.1 - 5e-19 66.8 14.2 0.0031 17.6 0.0 10.8 11 0 0 11 11 11 4 HEAT repeat Vac14_Fab1_bd PF12755.7 EKX39908.1 - 2.9e-10 40.6 3.0 0.00025 21.6 0.0 6.7 4 2 4 8 8 7 1 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 EKX39908.1 - 5.4e-08 32.9 7.1 0.52 10.2 0.0 7.7 5 3 3 8 8 8 2 Domain of unknown function (DUF3385) RIX1 PF08167.12 EKX39908.1 - 9.2e-08 32.0 0.2 0.39 10.4 0.0 5.6 4 2 0 4 4 4 1 rRNA processing/ribosome biogenesis IBN_N PF03810.19 EKX39908.1 - 3.4e-06 26.9 4.6 0.0016 18.3 0.0 6.3 6 1 1 7 7 6 1 Importin-beta N-terminal domain Cnd1 PF12717.7 EKX39908.1 - 3.5e-05 23.9 5.8 0.1 12.7 0.0 5.7 5 2 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 EKX39908.1 - 0.00013 21.8 1.7 3.2 7.9 0.1 5.9 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 EKX39908.1 - 0.00022 20.8 1.6 0.29 10.7 0.0 5.8 4 3 2 6 6 6 1 CLASP N terminal Importin_rep_6 PF18829.1 EKX39908.1 - 0.00052 20.1 0.2 0.0027 17.8 0.2 2.3 1 0 0 1 1 1 1 Importin repeat 6 MMS19_C PF12460.8 EKX39908.1 - 0.00097 18.4 8.2 0.57 9.2 0.1 4.6 3 3 2 5 5 5 2 RNAPII transcription regulator C-terminal Cnd3 PF12719.7 EKX39908.1 - 0.0019 17.5 3.9 11 5.1 0.0 4.9 5 0 0 5 5 5 0 Nuclear condensing complex subunits, C-term domain CTD_bind PF04818.13 EKX39908.1 - 0.0019 19.0 3.6 77 4.2 0.0 7.2 5 2 3 8 8 7 0 RNA polymerase II-binding domain. DUF577 PF04510.12 EKX39908.1 - 0.0029 17.5 0.8 0.036 14.0 0.0 3.3 4 0 0 4 4 4 1 Family of unknown function (DUF577) HEAT_PBS PF03130.16 EKX39908.1 - 0.0034 17.9 1.0 2.6 9.0 0.0 4.9 4 0 0 4 4 2 1 PBS lyase HEAT-like repeat RTP1_C1 PF10363.9 EKX39908.1 - 0.014 15.6 0.8 4.4 7.5 0.1 4.5 3 2 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 ELYS PF13934.6 EKX39908.1 - 1.5 8.8 9.3 1.2 9.1 0.6 3.2 2 1 0 3 3 3 0 Nuclear pore complex assembly Far-17a_AIG1 PF04750.14 EKX39912.1 - 2.5e-06 27.0 4.1 3e-06 26.7 4.1 1.2 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein GNAT_acetyltr_2 PF13718.6 EKX39913.1 - 2.2e-94 315.1 0.0 3.9e-94 314.3 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 EKX39913.1 - 1.2e-60 204.4 0.0 3.9e-60 202.7 0.0 1.9 2 0 0 2 2 2 1 Helicase tRNA_bind_2 PF13725.6 EKX39913.1 - 4e-49 167.4 0.0 7e-49 166.6 0.0 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain DUF1726 PF08351.11 EKX39913.1 - 2.5e-32 110.6 0.0 6.7e-32 109.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) DEAD PF00270.29 EKX39913.1 - 0.066 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF874 PF05917.11 EKX39914.1 - 0.0053 15.8 6.5 0.0083 15.2 6.5 1.2 1 0 0 1 1 1 1 Helicobacter pylori protein of unknown function (DUF874) SHE3 PF17078.5 EKX39914.1 - 0.0065 16.2 4.9 0.01 15.6 4.9 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 RTP PF02334.16 EKX39914.1 - 0.055 14.1 0.5 0.12 13.1 0.5 1.5 1 0 0 1 1 1 0 Replication terminator protein DUF812 PF05667.11 EKX39914.1 - 0.073 12.0 10.0 0.1 11.5 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF1640 PF07798.11 EKX39914.1 - 0.083 12.9 5.8 0.14 12.2 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Activator_LAG-3 PF11498.8 EKX39914.1 - 2.8 6.8 17.6 3.9 6.3 17.6 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Ank_5 PF13857.6 EKX39916.1 - 9.2e-20 70.5 0.0 4.6e-11 42.7 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX39916.1 - 2.2e-17 63.2 0.1 1e-12 48.3 0.0 1.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX39916.1 - 4.7e-16 58.4 0.2 5.8e-07 29.7 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EKX39916.1 - 2.4e-14 52.0 0.0 1.4e-06 28.1 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EKX39916.1 - 3.7e-14 53.1 0.1 9.9e-14 51.7 0.1 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) DEC-1_N PF04625.13 EKX39916.1 - 0.052 12.6 5.5 0.056 12.4 5.5 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region ubiquitin PF00240.23 EKX39917.1 - 0.019 14.7 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family zf-RING_5 PF14634.6 EKX39917.1 - 0.044 13.7 11.5 0.15 12.1 11.5 2.0 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EKX39917.1 - 0.073 13.1 8.1 0.24 11.5 8.1 2.0 1 0 0 1 1 1 0 RING-type zinc-finger WD40 PF00400.32 EKX39918.1 - 6.4e-22 77.4 4.8 1.4e-10 41.6 0.6 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX39918.1 - 2.4e-06 27.7 0.0 8.8e-05 22.7 0.0 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EKX39918.1 - 0.0036 16.0 0.1 0.0051 15.5 0.0 1.3 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Frtz PF11768.8 EKX39918.1 - 0.043 12.1 0.1 0.053 11.8 0.1 1.1 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 EKX39918.1 - 0.061 12.3 1.4 3.4 6.5 0.1 2.1 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EKX39918.1 - 0.076 11.7 0.0 0.077 11.7 0.0 1.1 1 0 0 1 1 1 0 Nup133 N terminal like Hydin_ADK PF17213.3 EKX39919.1 - 0.0027 18.0 4.9 0.0043 17.4 4.9 1.3 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain Sulf_transp PF04143.14 EKX39919.1 - 0.035 13.7 0.0 0.55 9.7 0.0 2.1 2 0 0 2 2 2 0 Sulphur transport Miga PF10265.9 EKX39919.1 - 0.16 10.9 1.5 0.18 10.8 1.5 1.1 1 0 0 1 1 1 0 Mitoguardin TFIIA PF03153.13 EKX39919.1 - 0.24 11.4 13.5 0.26 11.2 13.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MSP1_C PF07462.11 EKX39919.1 - 0.55 8.9 4.3 0.67 8.6 4.3 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Ndc1_Nup PF09531.10 EKX39919.1 - 0.72 8.5 8.2 0.86 8.2 8.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4366 PF14283.6 EKX39919.1 - 1.8 8.6 3.8 16 5.5 2.8 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4366) Totivirus_coat PF05518.11 EKX39919.1 - 1.8 6.5 10.1 2.2 6.2 10.1 1.0 1 0 0 1 1 1 0 Totivirus coat protein Lin-8 PF03353.15 EKX39919.1 - 2.3 7.7 6.6 3 7.3 6.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist ubiquitin PF00240.23 EKX39920.1 - 5.8e-09 35.6 0.0 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EKX39920.1 - 0.002 17.9 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 EKX39920.1 - 0.03 15.0 0.0 0.089 13.5 0.0 1.7 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_2 PF14560.6 EKX39920.1 - 0.12 12.8 0.0 0.27 11.7 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-like domain cNMP_binding PF00027.29 EKX39921.1 - 1.5e-17 63.5 0.0 2.4e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain FAM101 PF15068.6 EKX39923.1 - 0.02 14.8 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 FAM101 family Flg_hook PF02120.16 EKX39924.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK C2 PF00168.30 EKX39925.1 - 0.00013 22.2 0.0 0.00022 21.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain Cuticle_3 PF11018.8 EKX39926.1 - 0.083 13.1 12.1 0.15 12.3 12.1 1.4 1 0 0 1 1 1 0 Pupal cuticle protein C1 DUF2183 PF09949.9 EKX39926.1 - 0.17 12.2 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) C2 PF00168.30 EKX39928.1 - 0.00019 21.7 0.0 0.00042 20.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain CsbD PF05532.12 EKX39929.1 - 0.006 16.5 2.8 0.45 10.5 2.9 2.2 1 1 0 1 1 1 1 CsbD-like RmuC PF02646.16 EKX39929.1 - 0.024 13.8 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 RmuC family DUF948 PF06103.11 EKX39929.1 - 0.082 13.2 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) WASH_WAHD PF11945.8 EKX39929.1 - 0.083 12.4 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 WAHD domain of WASH complex DUF1664 PF07889.12 EKX39929.1 - 0.091 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3833 PF12915.7 EKX39929.1 - 0.13 11.8 1.1 6.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3833) DUF2183 PF09949.9 EKX39929.1 - 0.18 12.1 0.0 0.4 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) Alba PF01918.21 EKX39930.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Alba DUF3371 PF11851.8 EKX39930.1 - 0.34 12.0 4.8 0.57 11.3 4.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) Alba PF01918.21 EKX39931.1 - 0.029 14.2 0.0 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 Alba DUF3371 PF11851.8 EKX39931.1 - 0.37 11.9 4.8 0.62 11.2 4.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) Alba PF01918.21 EKX39932.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Alba DUF3371 PF11851.8 EKX39932.1 - 0.36 11.9 4.7 0.61 11.2 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) TFIID_20kDa PF03847.13 EKX39933.1 - 9.8e-31 106.1 0.1 1.1e-30 105.9 0.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.24 EKX39933.1 - 3.5e-06 27.4 0.0 4.1e-06 27.2 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EKX39933.1 - 1.6e-05 25.1 0.1 1.7e-05 25.0 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EKX39933.1 - 0.00044 20.3 0.0 0.00046 20.3 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 EKX39933.1 - 0.11 12.6 0.0 0.12 12.4 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold ANAPC4_WD40 PF12894.7 EKX39934.1 - 0.0074 16.6 0.2 0.25 11.6 0.1 2.7 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EKX39934.1 - 0.016 16.0 0.0 20 6.2 0.0 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat BBS2_Mid PF14783.6 EKX39934.1 - 0.016 15.2 0.0 0.039 14.0 0.0 1.7 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region PAP_assoc PF03828.19 EKX39935.1 - 0.00019 21.6 0.1 0.0031 17.7 0.1 2.5 1 1 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EKX39935.1 - 0.027 14.8 0.1 0.054 13.8 0.1 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain Thioredoxin PF00085.20 EKX39936.1 - 7.6e-19 67.6 0.0 9.9e-19 67.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.20 EKX39937.1 - 4.8e-21 74.7 0.0 9.4e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EKX39937.1 - 0.025 15.0 0.0 0.057 13.9 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EKX39937.1 - 0.15 12.3 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Peptidase_M76 PF09768.9 EKX39940.1 - 2.1e-14 53.7 4.9 3.1e-14 53.1 4.9 1.4 1 1 0 1 1 1 1 Peptidase M76 family Tox-MPTase2 PF15638.6 EKX39940.1 - 0.073 12.8 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 2 PBP1_TM PF14812.6 EKX39941.1 - 0.023 15.0 7.9 0.03 14.7 7.9 1.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 EKX39941.1 - 0.057 13.8 7.3 0.064 13.6 7.3 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3246 PF11596.8 EKX39941.1 - 0.15 11.5 3.3 0.15 11.5 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) YL1 PF05764.13 EKX39941.1 - 0.19 11.8 0.8 0.2 11.8 0.8 1.0 1 0 0 1 1 1 0 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 EKX39941.1 - 0.28 10.9 6.7 0.28 10.9 6.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 EKX39941.1 - 0.32 10.3 4.6 0.32 10.3 4.6 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 EKX39941.1 - 0.53 8.3 4.1 0.54 8.3 4.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 EKX39941.1 - 3.8 6.5 9.3 4.1 6.5 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Uso1_p115_C PF04871.13 EKX39941.1 - 5.2 7.5 8.2 7.2 7.0 8.2 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region PDEase_I_N PF08499.12 EKX39942.1 - 0.14 12.0 0.1 1.7 8.6 0.0 2.2 2 0 0 2 2 2 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal MOZ_SAS PF01853.18 EKX39944.1 - 6.7e-75 250.7 0.1 9.5e-75 250.2 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EKX39944.1 - 2.1e-18 65.7 0.7 4.4e-18 64.6 0.2 1.9 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 EKX39944.1 - 4e-10 39.4 0.3 9.6e-10 38.2 0.3 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 EKX39944.1 - 0.00058 20.2 0.0 0.0016 18.8 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MBOAT PF03062.19 EKX39945.1 - 1.6e-25 90.2 20.8 3.6e-25 89.1 20.8 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EKX39945.1 - 0.059 13.6 6.4 0.18 12.1 6.4 1.8 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family Pex14_N PF04695.13 EKX39945.1 - 0.11 13.1 0.1 3.8 8.1 0.1 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ank_4 PF13637.6 EKX39946.1 - 5.9e-13 49.1 0.0 8.8e-05 23.0 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX39946.1 - 2.5e-11 44.0 0.0 3.6e-07 30.7 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EKX39946.1 - 1.5e-09 37.9 0.0 0.0002 21.7 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EKX39946.1 - 2e-06 28.0 0.0 0.098 13.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX39946.1 - 0.00017 21.7 0.0 0.023 15.2 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeat Glyco_transf_92 PF01697.27 EKX39947.1 - 3.2e-22 79.4 0.1 4.5e-22 78.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 EKX39947.1 - 1.8e-12 47.6 0.5 4.3e-12 46.4 0.5 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Patatin PF01734.22 EKX39948.1 - 2e-11 44.5 4.5 1.6e-09 38.3 4.5 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase Rhomboid PF01694.22 EKX39949.1 - 3.7e-19 69.2 15.5 4.4e-19 69.0 15.5 1.0 1 0 0 1 1 1 1 Rhomboid family UPF0556 PF10572.9 EKX39950.1 - 7.9e-05 22.2 0.0 9.1e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0556 Rootletin PF15035.6 EKX39951.1 - 0.012 15.6 8.0 0.036 14.1 8.0 1.7 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF4795 PF16043.5 EKX39951.1 - 0.1 12.2 7.8 0.15 11.6 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) BLOC1S3 PF15753.5 EKX39951.1 - 0.16 12.1 4.0 0.24 11.5 3.5 1.4 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 eIF3_N PF09440.10 EKX39951.1 - 9.5 6.7 8.6 4.2 7.8 0.3 2.3 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain FtsJ PF01728.19 EKX39952.1 - 2.3e-24 86.5 0.0 1.1e-23 84.3 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase Myelin_MBP PF01669.17 EKX39953.1 - 0.015 15.9 1.1 0.025 15.2 1.1 1.5 1 1 0 1 1 1 0 Myelin basic protein Voltage_CLC PF00654.20 EKX39955.1 - 1e-81 275.0 28.2 1e-81 275.0 28.2 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EKX39955.1 - 5.4e-08 33.2 0.2 4.5e-05 23.8 0.1 2.5 2 0 0 2 2 2 2 CBS domain DUF1361 PF07099.11 EKX39955.1 - 0.0069 16.4 1.4 0.022 14.7 1.4 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1361) MARCKS PF02063.17 EKX39957.1 - 0.016 15.2 27.9 0.022 14.8 27.9 1.2 1 0 0 1 1 1 0 MARCKS family DUF1462 PF07315.11 EKX39957.1 - 0.21 11.9 1.5 13 6.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1462) GSHPx PF00255.19 EKX39958.1 - 1.9e-38 130.4 0.1 2.4e-38 130.0 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase RuvX PF03652.15 EKX39958.1 - 0.17 12.3 0.0 0.22 11.9 0.0 1.2 1 0 0 1 1 1 0 Holliday junction resolvase HECT PF00632.25 EKX39959.1 - 0.052 13.0 0.0 0.062 12.8 0.0 1.2 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) MtrG PF04210.13 EKX39959.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G Pkinase PF00069.25 EKX39962.1 - 3.3e-78 262.7 0.0 3.9e-78 262.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX39962.1 - 1.1e-42 146.2 0.0 1.3e-42 145.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX39962.1 - 1.3e-07 31.2 0.0 3.3e-07 29.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 EKX39962.1 - 0.00063 19.4 0.1 0.0011 18.6 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EKX39962.1 - 0.0027 16.7 0.1 0.0032 16.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 EKX39962.1 - 0.031 13.1 0.1 0.058 12.2 0.0 1.4 1 1 1 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.14 EKX39962.1 - 0.034 13.5 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX39962.1 - 0.1 12.5 0.1 0.35 10.8 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF572 PF04502.13 EKX39963.1 - 0.00096 18.9 14.8 0.0011 18.7 14.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) HSBP1 PF06825.12 EKX39964.1 - 0.0061 16.4 0.3 0.024 14.5 0.1 2.0 1 1 1 2 2 2 1 Heat shock factor binding protein 1 DUF2183 PF09949.9 EKX39964.1 - 0.043 14.1 0.0 0.13 12.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) HSBP1 PF06825.12 EKX39965.1 - 0.0034 17.2 0.2 0.014 15.3 0.1 2.0 1 1 1 2 2 2 1 Heat shock factor binding protein 1 Golgin_A5 PF09787.9 EKX39965.1 - 0.089 12.2 0.2 0.15 11.5 0.2 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 CLZ PF16526.5 EKX39965.1 - 0.15 12.5 0.1 0.69 10.3 0.1 2.0 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PMC2NT PF08066.12 EKX39965.1 - 0.2 12.4 1.4 0.98 10.2 0.5 2.2 2 0 0 2 2 2 0 PMC2NT (NUC016) domain SKA1 PF07160.12 EKX39965.1 - 0.26 11.1 1.6 1.1 9.0 0.1 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF16 PF01519.16 EKX39965.1 - 0.78 10.3 3.1 20 5.7 0.2 2.5 2 1 1 3 3 3 0 Protein of unknown function DUF16 Peptidase_S41 PF03572.18 EKX39966.1 - 7e-39 133.1 0.0 1.1e-38 132.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 EKX39966.1 - 0.00014 21.6 0.0 0.00039 20.2 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX39966.1 - 0.023 15.0 0.0 0.049 14.0 0.0 1.5 1 0 0 1 1 1 0 PDZ domain UPF0054 PF02130.17 EKX39967.1 - 4.1e-10 39.5 0.0 5.5e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 DS PF01916.17 EKX39967.1 - 0.15 11.3 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Deoxyhypusine synthase Exo_endo_phos PF03372.23 EKX39968.1 - 0.0042 16.6 0.0 0.0067 16.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ASH PF15780.5 EKX39969.1 - 2.8e-19 69.2 5.2 0.022 15.0 0.0 11.7 12 1 1 13 13 13 5 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 EKX39969.1 - 3.4e-16 59.3 0.9 2.7e-05 24.3 0.0 4.7 5 0 0 5 5 5 3 Flagellar-associated PapD-like fn3_5 PF06280.12 EKX39969.1 - 0.00025 21.7 0.1 0.51 11.1 0.0 4.2 4 0 0 4 4 4 2 Fn3-like domain Motile_Sperm PF00635.26 EKX39969.1 - 0.0052 16.6 0.0 2 8.3 0.0 4.4 4 0 0 4 4 4 1 MSP (Major sperm protein) domain Cation_ATPase PF13246.6 EKX39969.1 - 0.15 12.1 0.2 0.38 10.9 0.2 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) PKD_channel PF08016.12 EKX39971.1 - 2.2e-30 105.7 23.4 1.4e-29 103.1 23.4 2.1 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 EKX39971.1 - 1.9e-12 46.9 24.0 3.1e-12 46.3 24.0 1.3 1 0 0 1 1 1 1 Ion transport protein HA2 PF04408.23 EKX39972.1 - 9.1e-15 54.9 0.3 4.5e-14 52.6 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EKX39972.1 - 2.5e-14 53.6 0.1 1.5e-13 51.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EKX39972.1 - 1.7e-10 40.9 0.2 2.7e-10 40.3 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EKX39972.1 - 0.0011 19.3 0.2 0.0028 18.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EKX39972.1 - 0.0073 16.7 0.0 0.026 14.9 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EKX39972.1 - 0.014 15.6 0.1 5.6 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EKX39972.1 - 0.025 15.0 0.4 0.11 12.9 0.1 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 EKX39972.1 - 0.035 14.1 0.4 0.49 10.4 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_23 PF13476.6 EKX39972.1 - 0.068 13.7 0.4 0.15 12.6 0.1 1.6 2 0 0 2 2 2 0 AAA domain FtsJ PF01728.19 EKX39973.1 - 1.6e-41 142.3 0.0 2e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Pkinase PF00069.25 EKX39974.1 - 5.3e-71 239.1 0.0 6.8e-71 238.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX39974.1 - 8.8e-32 110.4 0.0 1.1e-31 110.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX39974.1 - 5.7e-05 22.6 0.0 8.7e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EKX39974.1 - 0.00092 18.3 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EKX39974.1 - 0.039 13.9 0.0 0.1 12.5 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family FIBP PF05427.11 EKX39974.1 - 0.062 12.6 0.2 0.096 12.0 0.2 1.2 1 0 0 1 1 1 0 Acidic fibroblast growth factor binding (FIBP) PBP_like_2 PF12849.7 EKX39975.1 - 1.8e-27 96.7 0.2 2.2e-27 96.5 0.2 1.0 1 0 0 1 1 1 1 PBP superfamily domain PBP_like PF12727.7 EKX39975.1 - 0.0076 15.4 0.4 0.037 13.1 0.1 2.0 2 0 0 2 2 2 1 PBP superfamily domain EppA_BapA PF07268.11 EKX39977.1 - 0.041 13.8 0.0 2.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Exported protein precursor (EppA/BapA) TMPIT PF07851.13 EKX39977.1 - 0.06 12.6 7.7 0.1 11.8 7.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein VBS PF08913.10 EKX39977.1 - 0.12 12.8 1.4 0.25 11.8 1.4 1.5 1 0 0 1 1 1 0 Vinculin Binding Site Exonuc_VII_L PF02601.15 EKX39977.1 - 0.17 11.4 3.1 0.26 10.8 3.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3918 PF13056.6 EKX39977.1 - 0.33 10.6 3.3 0.73 9.5 3.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) DUF2200 PF09966.9 EKX39978.1 - 0.0048 17.0 0.4 0.033 14.3 0.4 2.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2200) Csm1_N PF18504.1 EKX39978.1 - 0.032 14.6 0.6 0.032 14.6 0.6 10.9 7 3 5 12 12 12 0 Csm1 N-terminal domain DUF3860 PF12976.7 EKX39978.1 - 0.27 11.3 2.6 3.1 7.9 0.2 3.3 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3860) ETC_C1_NDUFA5 PF04716.14 EKX39979.1 - 3.4e-06 26.8 0.0 5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region FMN_dh PF01070.18 EKX39980.1 - 8.9e-131 436.0 0.0 1.1e-130 435.7 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EKX39980.1 - 2.6e-06 26.7 0.1 4.3e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EKX39980.1 - 0.00016 21.0 0.1 0.00026 20.2 0.1 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 EKX39980.1 - 0.093 12.2 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein Thr_synth_N PF14821.6 EKX39981.1 - 3.3e-19 68.9 0.0 7.2e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 EKX39981.1 - 1.1e-14 54.6 0.0 1.8e-14 53.8 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GIT_SHD PF08518.11 EKX39981.1 - 0.12 12.0 0.6 0.72 9.5 0.3 2.3 2 0 0 2 2 2 0 Spa2 homology domain (SHD) of GIT YjeF_N PF03853.15 EKX39981.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Myco_arth_vir_N PF09610.10 EKX39981.1 - 0.22 11.6 0.3 0.42 10.7 0.3 1.4 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) Aldose_epim PF01263.20 EKX39982.1 - 4.4e-51 174.0 0.0 5e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Pkinase PF00069.25 EKX39984.1 - 2.9e-45 154.7 0.0 3.6e-45 154.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX39984.1 - 2.2e-26 92.7 0.0 2.6e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX39984.1 - 3.9e-05 23.7 0.0 4.5e-05 23.5 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EKX39984.1 - 0.0024 17.5 0.1 0.0032 17.1 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EKX39984.1 - 0.0052 16.1 0.0 0.0081 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EKX39984.1 - 0.0078 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EKX39984.1 - 0.018 14.4 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EKX39984.1 - 0.023 13.5 0.0 0.068 11.9 0.0 1.6 1 1 1 2 2 2 0 Fungal protein kinase Pan_kinase PF03309.14 EKX39984.1 - 0.045 13.6 0.0 0.055 13.3 0.0 1.2 1 0 0 1 1 1 0 Type III pantothenate kinase Choline_kinase PF01633.20 EKX39984.1 - 0.047 13.3 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Cation_ATPase_N PF00690.26 EKX39985.1 - 0.027 14.1 0.0 0.21 11.3 0.0 2.2 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus DUF2475 PF10629.9 EKX39986.1 - 0.017 15.3 0.5 23 5.3 0.0 4.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2475) Pkinase PF00069.25 EKX39987.1 - 1.3e-77 260.8 0.1 1.4e-77 260.6 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX39987.1 - 8.7e-40 136.6 0.1 1e-39 136.4 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX39987.1 - 8.8e-06 25.2 0.2 1.3e-05 24.6 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EKX39987.1 - 0.00054 18.8 0.3 0.0014 17.5 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EKX39987.1 - 0.0026 17.7 0.0 0.0085 16.0 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EKX39987.1 - 0.005 16.2 0.0 0.01 15.2 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EKX39987.1 - 0.034 13.1 0.2 0.046 12.7 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 EKX39987.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase ParA PF10609.9 EKX39988.1 - 8.5e-94 313.6 0.2 1e-93 313.3 0.2 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EKX39988.1 - 9.4e-12 45.1 0.0 3.4e-11 43.3 0.0 1.8 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EKX39988.1 - 5.7e-09 36.1 0.2 3.2e-08 33.7 0.2 1.9 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 EKX39988.1 - 2.1e-08 33.8 0.0 5.1e-08 32.5 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 EKX39988.1 - 2e-07 30.5 1.6 8.2e-07 28.5 1.1 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 EKX39988.1 - 0.00012 21.7 0.0 0.00045 19.8 0.0 1.8 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 EKX39988.1 - 0.00027 20.0 1.2 0.00037 19.5 1.2 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Fer4_NifH PF00142.18 EKX39988.1 - 0.00089 18.8 0.1 0.0036 16.8 0.2 1.8 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family APS_kinase PF01583.20 EKX39988.1 - 0.0064 16.4 0.1 0.0096 15.8 0.1 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.12 EKX39988.1 - 0.021 14.1 0.2 0.23 10.7 0.3 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 EKX39988.1 - 0.025 14.2 0.3 0.04 13.5 0.3 1.2 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EKX39988.1 - 0.039 13.6 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_26 PF13500.6 EKX39988.1 - 0.061 13.1 0.4 2.5 7.9 0.7 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EKX39988.1 - 0.072 13.5 0.3 0.1 13.0 0.3 1.2 1 0 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 EKX39988.1 - 0.075 12.8 0.2 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein KTI12 PF08433.10 EKX39988.1 - 0.15 11.5 0.1 0.23 10.9 0.1 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NB-ARC PF00931.22 EKX39988.1 - 0.27 10.4 1.2 0.56 9.3 0.8 1.7 2 0 0 2 2 2 0 NB-ARC domain BDV_P24 PF06595.11 EKX39989.1 - 0.09 12.7 0.2 0.15 12.0 0.2 1.2 1 0 0 1 1 1 0 Borna disease virus P24 protein Kinesin PF00225.23 EKX39990.1 - 2.8e-95 319.0 0.0 3.3e-95 318.8 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX39990.1 - 2.4e-20 73.0 0.0 4.3e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Mce4_CUP1 PF11887.8 EKX39990.1 - 0.09 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative Glyoxalase PF00903.25 EKX39991.1 - 0.00019 21.7 0.0 0.001 19.3 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CD4-extracel PF09191.10 EKX39991.1 - 0.065 13.7 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 CD4, extracellular DUF641 PF04859.12 EKX39993.1 - 0.067 13.5 25.1 1.1 9.6 0.4 4.7 3 1 1 4 4 4 0 Plant protein of unknown function (DUF641) Fib_alpha PF08702.10 EKX39993.1 - 0.076 13.2 17.7 1.5 9.0 0.1 4.7 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family DIMCO_N PF16844.5 EKX39993.1 - 0.079 13.3 2.9 0.22 11.9 0.5 2.9 2 1 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal AKNA PF12443.8 EKX39993.1 - 1.5 9.5 10.6 0.72 10.5 0.5 4.5 4 0 0 4 4 4 0 AT-hook-containing transcription factor USP8_interact PF08941.10 EKX39993.1 - 3.3 7.5 18.2 0.96 9.2 0.1 4.5 3 1 2 5 5 5 0 USP8 interacting eRF1_3 PF03465.15 EKX39993.1 - 4.6 7.8 6.5 2.1 8.9 0.1 3.1 2 1 0 2 2 2 0 eRF1 domain 3 Spc7 PF08317.11 EKX39993.1 - 6.1 5.6 32.6 1.9 7.3 0.2 4.3 2 1 2 5 5 5 0 Spc7 kinetochore protein MORN PF02493.20 EKX39994.1 - 5.1e-22 76.4 18.8 6.7e-07 28.8 0.5 4.1 4 0 0 4 4 4 4 MORN repeat Ribosomal_L23 PF00276.20 EKX39995.1 - 1.1e-12 48.1 0.1 1.8e-12 47.5 0.1 1.4 1 1 0 1 1 1 1 Ribosomal protein L23 RE_ApaLI PF09499.10 EKX39995.1 - 0.12 12.1 1.1 0.13 11.9 0.1 1.5 2 0 0 2 2 2 0 ApaLI-like restriction endonuclease zf-CSL PF05207.13 EKX39996.1 - 1e-15 57.2 0.4 1.1e-15 57.1 0.4 1.0 1 0 0 1 1 1 1 CSL zinc finger zf-RING_4 PF14570.6 EKX39996.1 - 0.055 13.3 1.4 0.093 12.5 1.4 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain GTP_EFTU PF00009.27 EKX39997.1 - 0.0018 17.8 0.0 0.0049 16.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EKX39998.1 - 4.2e-09 36.5 0.0 4.4e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EKX39998.1 - 0.0029 17.7 1.1 0.012 15.6 0.9 1.8 1 1 1 2 2 2 1 Dynamin family AIG1 PF04548.16 EKX39998.1 - 0.02 14.2 0.4 0.024 14.0 0.4 1.3 1 1 0 1 1 1 0 AIG1 family RsgA_GTPase PF03193.16 EKX39998.1 - 0.02 14.8 0.0 0.026 14.5 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase FeoB_N PF02421.18 EKX39998.1 - 0.086 12.4 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Ferrous iron transport protein B tRNA_anti-codon PF01336.25 EKX39999.1 - 7.3e-08 32.3 0.7 1.5e-07 31.3 0.7 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RPA_C PF08784.11 EKX39999.1 - 9.2e-07 29.5 0.0 1.2e-05 26.0 0.0 2.2 2 0 0 2 2 2 1 Replication protein A C terminal RMI2 PF16100.5 EKX39999.1 - 9.3e-05 22.3 0.2 0.00014 21.7 0.2 1.2 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 tRNA_anti_2 PF13742.6 EKX39999.1 - 0.00021 21.4 0.6 0.039 14.2 0.1 2.3 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 EKX39999.1 - 0.062 13.0 0.2 0.093 12.4 0.2 1.2 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 PseudoU_synth_1 PF01416.20 EKX40000.1 - 5.2e-20 71.9 0.1 3.7e-13 49.9 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase DSPc PF00782.20 EKX40004.1 - 6.1e-05 22.8 0.1 8.2e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EKX40004.1 - 0.00019 21.5 0.6 0.0003 20.8 0.6 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EKX40004.1 - 0.0026 17.4 0.0 0.003 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX40004.1 - 0.043 13.9 0.0 0.06 13.5 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Activin_recp PF01064.23 EKX40004.1 - 0.068 14.3 0.2 0.17 13.0 0.0 1.7 2 0 0 2 2 2 0 Activin types I and II receptor domain Y_phosphatase2 PF03162.13 EKX40004.1 - 0.22 11.1 0.6 0.27 10.8 0.6 1.4 1 1 0 1 1 1 0 Tyrosine phosphatase family TMEM234 PF10639.9 EKX40005.1 - 9.7e-41 138.5 1.5 1.1e-40 138.3 1.5 1.0 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 EKX40005.1 - 1.2e-05 25.5 5.8 0.00055 20.1 6.6 2.0 1 1 1 2 2 2 2 EamA-like transporter family Gram_pos_anchor PF00746.21 EKX40005.1 - 0.82 9.7 2.6 0.41 10.6 0.5 1.6 2 0 0 2 2 2 0 LPXTG cell wall anchor motif fn3 PF00041.21 EKX40006.1 - 1.7e-47 159.6 34.3 9.9e-09 35.4 0.0 18.5 19 1 0 19 19 19 8 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 EKX40006.1 - 3.9e-15 56.2 8.3 0.015 15.8 0.0 11.7 14 2 1 15 15 15 3 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 EKX40006.1 - 0.0014 18.9 0.0 0.89 10.0 0.0 3.3 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2369) fn3_2 PF16893.5 EKX40006.1 - 0.0044 17.1 0.1 4.3 7.6 0.0 5.5 7 1 0 7 7 7 1 Fibronectin type III domain F5_F8_type_C PF00754.25 EKX40006.1 - 0.016 15.3 0.1 1.5 9.0 0.1 2.9 2 0 0 2 2 2 0 F5/8 type C domain LysM PF01476.20 EKX40006.1 - 0.023 14.7 0.0 0.56 10.3 0.0 2.7 2 0 0 2 2 2 0 LysM domain PhoD_N PF16655.5 EKX40006.1 - 0.075 13.6 0.0 28 5.3 0.0 4.1 4 0 0 4 4 4 0 PhoD-like phosphatase, N-terminal domain Tissue_fac PF01108.17 EKX40006.1 - 0.12 12.2 4.4 5.2 7.0 0.1 4.8 6 0 0 6 6 6 0 Tissue factor fn3 PF00041.21 EKX40007.1 - 1.5e-16 60.5 11.6 3.4e-06 27.3 1.1 5.4 5 0 0 5 5 5 4 Fibronectin type III domain Tissue_fac PF01108.17 EKX40007.1 - 0.016 15.1 9.0 0.25 11.2 0.9 3.8 3 1 0 3 3 3 0 Tissue factor Glyco_transf_25 PF01755.17 EKX40008.1 - 1.5e-06 28.2 0.0 2.3e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) UVR PF02151.19 EKX40009.1 - 0.0002 21.0 12.0 0.0086 15.8 3.1 2.4 2 0 0 2 2 2 2 UvrB/uvrC motif DPPIV_N PF00930.21 EKX40009.1 - 0.0018 17.1 1.8 0.043 12.6 0.0 3.0 4 0 0 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.12 EKX40009.1 - 0.0084 16.0 16.3 0.55 10.2 0.1 5.7 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 EKX40009.1 - 0.026 14.8 0.0 3.6 7.9 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain COPIIcoated_ERV PF07970.12 EKX40010.1 - 4.8e-46 157.4 0.4 7.7e-46 156.7 0.4 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EKX40010.1 - 2.2e-28 98.4 0.2 4.1e-28 97.6 0.2 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Glycos_transf_2 PF00535.26 EKX40011.1 - 5.3e-15 55.6 0.0 8.3e-14 51.7 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EKX40011.1 - 0.0011 19.0 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EKX40011.1 - 0.027 13.9 0.0 1.7 8.1 0.0 2.6 2 1 0 2 2 2 0 Glycosyltransferase like family 2 PDZ_6 PF17820.1 EKX40012.1 - 8.3e-21 73.6 0.6 2e-10 40.3 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX40012.1 - 3e-19 69.1 0.0 2.2e-09 37.5 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 EKX40012.1 - 1.6e-11 44.4 0.2 8e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 EKX40012.1 - 0.027 14.4 0.0 2.2 8.3 0.0 2.5 2 0 0 2 2 2 0 Tricorn protease PDZ domain GRASP55_65 PF04495.14 EKX40012.1 - 0.099 13.0 0.0 0.55 10.6 0.0 2.0 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain Fez1 PF06818.15 EKX40012.1 - 1.6 9.1 24.2 3 8.3 24.2 1.3 1 0 0 1 1 1 0 Fez1 Peptidase_S46 PF10459.9 EKX40012.1 - 5.3 5.6 14.3 7.4 5.1 14.3 1.1 1 0 0 1 1 1 0 Peptidase S46 HalX PF08663.10 EKX40012.1 - 6.5 7.1 12.2 0.9 9.9 0.1 2.9 3 0 0 3 3 3 0 HalX domain CHDCT2 PF08074.11 EKX40012.1 - 8.4 6.5 9.4 4.1 7.5 1.3 2.9 2 1 1 3 3 3 0 CHDCT2 (NUC038) domain NurA PF09376.10 EKX40013.1 - 0.097 12.3 0.0 5.4 6.6 0.0 2.2 2 0 0 2 2 2 0 NurA domain Beta_elim_lyase PF01212.21 EKX40014.1 - 4.3e-79 265.8 0.0 5.6e-79 265.5 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EKX40014.1 - 1.7e-09 37.4 0.0 2.5e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EKX40014.1 - 1.1e-06 28.2 0.1 0.0025 17.2 0.0 2.1 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EKX40014.1 - 1.8e-05 23.5 0.0 2.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme PAN_1 PF00024.26 EKX40016.1 - 0.062 13.3 7.7 0.066 13.2 1.9 2.8 3 0 0 3 3 3 0 PAN domain PDZ_2 PF13180.6 EKX40016.1 - 0.078 13.3 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 EKX40016.1 - 0.086 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 PDZ domain Pkinase PF00069.25 EKX40017.1 - 8.5e-69 231.8 0.0 1.2e-68 231.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX40017.1 - 6.1e-34 117.5 0.0 8e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX40017.1 - 7.7e-06 25.4 0.0 0.00033 20.1 0.0 2.4 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EKX40017.1 - 0.0008 18.3 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EKX40017.1 - 0.0019 17.6 0.1 0.0044 16.4 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX40017.1 - 0.11 12.5 0.0 0.2 11.5 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Ammonium_transp PF00909.21 EKX40018.1 - 1.5e-115 386.1 30.7 1.7e-115 385.9 30.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family TPR_1 PF00515.28 EKX40019.1 - 5.4e-26 89.3 4.5 7.7e-07 28.7 0.1 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 EKX40019.1 - 5.6e-26 90.0 7.9 2e-06 27.4 1.0 6.3 5 1 1 6 6 6 4 TPR repeat TPR_2 PF07719.17 EKX40019.1 - 1.9e-25 86.9 2.4 1.5e-06 27.9 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 EKX40019.1 - 1.1e-20 72.4 4.8 0.0014 18.9 0.0 6.8 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 EKX40019.1 - 1.1e-19 68.9 2.8 0.00011 22.2 0.1 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 EKX40019.1 - 2.3e-19 68.4 2.7 0.00024 21.6 0.5 7.2 4 1 3 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 EKX40019.1 - 7.7e-15 55.3 2.0 0.00036 21.1 0.2 4.0 2 2 1 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 EKX40019.1 - 5e-13 49.4 5.8 0.0075 16.7 1.8 4.3 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX40019.1 - 6.3e-13 48.8 3.5 0.0001 22.5 0.0 4.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 EKX40019.1 - 1.9e-10 40.9 6.1 0.023 15.0 0.2 4.7 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 EKX40019.1 - 4.2e-10 39.6 2.1 0.033 14.3 1.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX40019.1 - 1.1e-07 31.5 3.0 0.2 11.6 0.0 4.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX40019.1 - 1.4e-07 31.0 5.2 0.16 12.0 0.1 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX40019.1 - 5.6e-07 29.8 1.3 2 9.2 0.0 6.5 8 0 0 8 8 7 1 Tetratricopeptide repeat NRDE-2 PF08424.10 EKX40019.1 - 0.00034 19.9 0.2 0.11 11.5 0.0 2.3 2 0 0 2 2 2 2 NRDE-2, necessary for RNA interference TPR_15 PF13429.6 EKX40019.1 - 0.0096 15.2 0.1 5 6.2 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF4248 PF14053.6 EKX40019.1 - 0.023 14.7 0.2 0.73 9.9 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4248) ANAPC3 PF12895.7 EKX40019.1 - 0.044 14.0 1.9 4.8 7.5 0.1 2.7 3 0 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PPTA PF01239.22 EKX40019.1 - 0.12 12.1 0.2 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat MAS20 PF02064.15 EKX40019.1 - 0.12 12.4 0.2 6.2 6.9 0.0 3.0 2 1 0 3 3 2 0 MAS20 protein import receptor DUF4192 PF13830.6 EKX40019.1 - 0.17 11.9 5.8 1.3 9.0 0.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4192) SP_C-Propep PF08999.10 EKX40020.1 - 0.078 12.8 1.9 0.14 11.9 1.9 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Arm PF00514.23 EKX40021.1 - 0.0071 16.4 4.0 0.5 10.5 0.0 3.7 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Laminin_G_3 PF13385.6 EKX40022.1 - 2.9e-11 43.7 0.1 4.6e-10 39.8 0.1 2.2 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily LysM PF01476.20 EKX40022.1 - 0.00072 19.6 0.0 0.0024 17.9 0.0 1.9 2 0 0 2 2 2 1 LysM domain CBP_BcsN PF17038.5 EKX40022.1 - 0.043 13.2 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsN Pkinase PF00069.25 EKX40023.1 - 2.3e-61 207.5 0.0 2.7e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX40023.1 - 1e-23 83.9 0.0 1.8e-23 83.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX40023.1 - 0.0079 15.5 0.0 0.12 11.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EKX40023.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family S1 PF00575.23 EKX40024.1 - 3.4e-40 136.2 0.9 1.3e-20 73.5 0.1 3.2 3 0 0 3 3 3 3 S1 RNA binding domain S1_2 PF13509.6 EKX40024.1 - 0.042 13.9 0.1 8 6.6 0.0 4.3 4 2 1 5 5 5 0 S1 domain PTS_IIA PF02255.16 EKX40025.1 - 0.42 10.7 25.9 0.17 11.9 3.2 6.2 5 2 2 7 7 7 0 PTS system, Lactose/Cellobiose specific IIA subunit YfdX PF10938.8 EKX40025.1 - 0.53 10.2 17.8 0.53 10.2 0.1 4.1 4 0 0 4 4 4 0 YfdX protein PBP_sp32 PF07222.12 EKX40025.1 - 1.2 8.6 10.8 5.9 6.3 10.8 2.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF1912 PF08930.10 EKX40025.1 - 5.3 7.3 8.0 0.24 11.6 0.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1912) TP2 PF01254.18 EKX40026.1 - 0.12 13.0 8.3 0.17 12.5 8.3 1.2 1 0 0 1 1 1 0 Nuclear transition protein 2 DpnD-PcfM PF14207.6 EKX40026.1 - 0.42 10.5 3.6 0.51 10.3 0.6 2.3 2 0 0 2 2 2 0 DpnD/PcfM-like protein DUF4820 PF16091.5 EKX40026.1 - 0.68 9.3 5.6 0.95 8.8 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) GRAM PF02893.20 EKX40027.1 - 0.00089 19.1 0.2 0.083 12.8 0.0 2.5 2 0 0 2 2 2 1 GRAM domain LAP1C PF05609.12 EKX40027.1 - 0.0045 16.1 13.3 0.0064 15.6 13.3 1.2 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) CDC27 PF09507.10 EKX40027.1 - 0.0051 16.3 22.5 0.0066 15.9 22.5 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 GREB1 PF15782.5 EKX40027.1 - 0.017 12.3 5.1 0.021 12.0 5.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF5401 PF17380.2 EKX40027.1 - 0.065 11.3 45.1 0.1 10.7 45.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) NYD-SP28_assoc PF14775.6 EKX40027.1 - 0.11 12.6 5.0 0.52 10.5 5.0 2.2 1 0 0 1 1 1 0 Sperm tail C-terminal domain GTF2I PF02946.14 EKX40027.1 - 0.12 12.4 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 GTF2I-like repeat MDM1 PF15501.6 EKX40027.1 - 0.71 8.9 33.7 1.1 8.4 33.7 1.2 1 0 0 1 1 1 0 Nuclear protein MDM1 Ferlin_C PF16165.5 EKX40027.1 - 1.6 8.7 14.7 1.2e+02 2.6 15.3 2.9 2 1 0 2 2 2 0 Ferlin C-terminus GBP PF02263.19 EKX40028.1 - 2.5e-31 108.9 0.0 4.7e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 EKX40028.1 - 2.4e-05 24.4 0.0 6.1e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DHHC PF01529.20 EKX40030.1 - 9e-12 45.2 17.7 9e-12 45.2 17.7 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase DZR PF12773.7 EKX40030.1 - 2.9 8.0 11.2 0.093 12.8 2.8 2.4 2 0 0 2 2 2 0 Double zinc ribbon YabA PF06156.13 EKX40031.1 - 0.061 14.0 3.1 0.1 13.3 2.5 1.7 2 0 0 2 2 2 0 Initiation control protein YabA Miff PF05644.11 EKX40031.1 - 0.29 10.7 4.6 0.059 13.0 0.7 1.7 2 0 0 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff Totivirus_coat PF05518.11 EKX40031.1 - 0.39 8.7 3.8 0.45 8.5 3.8 1.2 1 0 0 1 1 1 0 Totivirus coat protein EMP24_GP25L PF01105.24 EKX40031.1 - 0.56 10.1 4.0 0.15 12.0 1.0 1.6 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Pkinase PF00069.25 EKX40032.1 - 1.2e-55 188.7 0.1 1.5e-55 188.4 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX40032.1 - 1.9e-44 151.9 0.0 2.4e-44 151.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX40032.1 - 6.6e-07 28.9 0.0 1.4e-06 27.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EKX40032.1 - 0.00056 18.8 0.1 0.0016 17.3 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 EKX40032.1 - 0.0026 16.8 0.6 0.013 14.5 0.6 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EKX40032.1 - 0.018 14.4 0.1 0.036 13.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PseudoU_synth_1 PF01416.20 EKX40033.1 - 5.1e-06 26.9 1.1 0.037 14.5 0.1 3.8 3 1 1 4 4 4 3 tRNA pseudouridine synthase HIM1 PF08732.10 EKX40033.1 - 0.11 11.9 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 HIM1 CarboxypepD_reg PF13620.6 EKX40035.1 - 3.1e-54 181.2 8.9 3e-06 27.4 1.0 10.3 10 1 0 10 10 10 9 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 EKX40035.1 - 1e-24 86.9 6.6 0.019 15.2 0.3 9.9 9 1 1 10 10 10 5 SdrD B-like domain DUF2012 PF09430.10 EKX40035.1 - 1.1e-21 77.2 1.1 4.1e-06 26.9 0.0 6.7 4 2 2 7 7 7 4 Protein of unknown function (DUF2012) CarbopepD_reg_2 PF13715.6 EKX40035.1 - 6.1e-21 74.2 14.1 0.00049 20.0 0.4 8.9 9 0 0 9 9 9 5 CarboxypepD_reg-like domain SpaA PF17802.1 EKX40035.1 - 9.4e-13 48.3 0.2 0.61 10.5 0.0 7.7 8 0 0 8 8 8 3 Prealbumin-like fold domain fn3_3 PF14686.6 EKX40035.1 - 5.5e-07 29.3 0.9 0.087 12.6 0.0 5.2 6 0 0 6 6 5 2 Polysaccharide lyase family 4, domain II MG4 PF17789.1 EKX40035.1 - 3.8e-05 23.7 0.0 0.14 12.4 0.0 4.7 5 0 0 5 5 5 1 Macroglobulin domain MG4 MetallophosN PF16371.5 EKX40035.1 - 0.00024 21.3 6.8 0.086 13.1 0.5 5.7 6 0 0 6 6 6 1 N terminal of Calcineurin-like phosphoesterase TTR-52 PF01060.23 EKX40035.1 - 0.0018 18.9 0.0 13 6.6 0.0 5.1 5 0 0 5 5 5 0 Transthyretin-like family phage_tail_N PF08400.10 EKX40035.1 - 0.0021 18.0 0.4 4.5 7.3 0.0 3.8 3 0 0 3 3 3 1 Prophage tail fibre N-terminal Dioxygenase_C PF00775.21 EKX40035.1 - 0.0022 17.4 0.0 11 5.4 0.0 4.3 4 0 0 4 4 4 0 Dioxygenase DUF2846 PF11008.8 EKX40035.1 - 0.0031 17.5 1.2 33 4.6 0.0 5.3 6 0 0 6 6 6 0 Protein of unknown function (DUF2846) Big_1 PF02369.16 EKX40035.1 - 0.0077 16.2 9.9 1.8 8.7 0.0 5.5 6 0 0 6 6 5 1 Bacterial Ig-like domain (group 1) PEGA PF08308.11 EKX40035.1 - 0.0077 16.1 1.2 10 6.1 0.1 4.4 5 0 0 5 5 5 0 PEGA domain ChitinaseA_N PF08329.10 EKX40035.1 - 0.0088 15.7 0.8 0.26 11.0 0.1 3.2 3 0 0 3 3 3 1 Chitinase A, N-terminal domain Y_Y_Y PF07495.13 EKX40035.1 - 0.0093 15.9 3.3 0.34 10.9 0.1 4.2 5 0 0 5 5 5 1 Y_Y_Y domain fn3 PF00041.21 EKX40035.1 - 0.027 14.8 0.0 0.27 11.6 0.0 2.8 2 0 0 2 2 2 0 Fibronectin type III domain BiPBP_C PF06832.12 EKX40035.1 - 0.043 13.9 0.0 2 8.5 0.0 3.3 4 0 0 4 4 2 0 Penicillin-Binding Protein C-terminus Family Big_7 PF17957.1 EKX40035.1 - 0.11 13.3 4.1 0.95 10.3 0.5 3.7 3 0 0 3 3 3 0 Bacterial Ig domain Big_3_5 PF16640.5 EKX40035.1 - 0.12 12.5 5.4 2.5 8.4 0.0 3.9 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) FtsK_4TM PF13491.6 EKX40036.1 - 0.12 12.0 0.5 0.17 11.5 0.1 1.4 2 0 0 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE DUF1918 PF08940.11 EKX40037.1 - 0.14 11.8 0.1 0.32 10.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) HalX PF08663.10 EKX40037.1 - 0.74 10.2 5.8 0.23 11.8 1.3 2.2 1 1 1 2 2 2 0 HalX domain DUF1843 PF08898.10 EKX40037.1 - 3.3 8.3 9.4 0.33 11.5 1.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) LPD30 PF18850.1 EKX40037.1 - 4.4 7.1 10.2 3.3 7.5 6.7 2.3 2 1 0 2 2 2 0 Large polyvalent protein associated domain 30 APG6_N PF17675.1 EKX40037.1 - 7.2 7.2 14.5 1.1 9.7 2.1 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region LRR_8 PF13855.6 EKX40039.1 - 1.7e-83 274.3 41.6 2.7e-19 68.7 2.3 6.1 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 EKX40039.1 - 7.2e-46 153.4 57.1 2.3e-08 34.2 0.5 7.3 1 1 11 12 12 12 12 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX40039.1 - 7.9e-28 97.0 0.0 3e-09 36.9 0.0 3.1 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EKX40039.1 - 7.3e-15 53.2 19.7 0.068 13.7 0.2 10.0 10 1 0 10 10 10 4 Leucine Rich Repeat LRR_9 PF14580.6 EKX40039.1 - 4.1e-05 23.2 0.0 0.84 9.1 0.0 3.5 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 EKX40039.1 - 4.2e-05 23.3 18.6 1.4 9.1 0.2 6.9 8 0 0 8 8 8 4 Leucine Rich repeat CSTF_C PF14304.6 EKX40039.1 - 0.0015 18.1 4.3 38 4.0 0.1 6.5 7 0 0 7 7 7 0 Transcription termination and cleavage factor C-terminal Aldolase PF01081.19 EKX40039.1 - 0.0058 16.1 0.0 9.1 5.6 0.0 3.2 2 1 2 4 4 4 3 KDPG and KHG aldolase SpoU_sub_bind PF08032.12 EKX40041.1 - 0.12 12.7 3.5 1.1 9.6 0.0 2.9 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding DUF4407 PF14362.6 EKX40041.1 - 0.19 11.0 11.7 0.3 10.4 11.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SPATA1_C PF15743.5 EKX40041.1 - 0.3 11.1 17.2 0.98 9.5 17.2 1.8 1 1 0 1 1 1 0 Spermatogenesis-associated C-terminus Spc7 PF08317.11 EKX40041.1 - 1.2 7.9 22.3 0.079 11.8 16.1 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein WD40_alt PF14077.6 EKX40041.1 - 3.1 7.7 5.0 0.48 10.3 0.3 2.1 3 0 0 3 3 3 0 Alternative WD40 repeat motif DUF1043 PF06295.12 EKX40041.1 - 3.3 7.7 15.8 12 5.9 11.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) KASH_CCD PF14662.6 EKX40041.1 - 3.4 7.5 25.4 1.5 8.7 21.1 2.2 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH FUSC PF04632.12 EKX40041.1 - 4 5.9 6.5 6.4 5.2 6.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family kleA_kleC PF17383.2 EKX40041.1 - 4.2 7.8 13.2 4 7.8 6.1 2.9 2 1 1 3 3 2 0 Uncharacterized KorC regulated protein A Sec8_exocyst PF04048.14 EKX40041.1 - 5.2 7.0 11.0 0.22 11.4 3.4 2.5 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain MCPsignal PF00015.21 EKX40041.1 - 5.3 6.8 11.7 1.2 9.0 2.1 2.7 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Seadorna_VP7 PF07387.11 EKX40043.1 - 0.0015 17.6 0.0 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Ank_5 PF13857.6 EKX40043.1 - 0.0062 16.8 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Glyco_tranf_2_4 PF13704.6 EKX40044.1 - 2.3e-08 34.4 0.2 4.8e-08 33.4 0.2 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glycos_transf_2 PF00535.26 EKX40044.1 - 3.9e-08 33.3 0.4 7.8e-08 32.3 0.4 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EKX40044.1 - 0.0047 16.8 0.1 0.0077 16.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 HicB PF05534.12 EKX40044.1 - 0.053 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 HicB family Bap31_Bap29_C PF18035.1 EKX40046.1 - 0.54 10.3 2.3 0.39 10.8 0.3 1.8 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain IBR PF01485.21 EKX40047.1 - 4.2e-10 39.7 33.0 1.1e-08 35.2 12.8 3.6 4 0 0 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EKX40047.1 - 2.2e-05 24.7 29.7 0.0012 19.2 3.3 4.0 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.6 EKX40047.1 - 0.015 15.1 1.8 0.015 15.1 1.8 4.1 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX40047.1 - 0.024 14.5 31.2 0.025 14.4 1.0 4.2 3 2 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX40047.1 - 0.07 13.2 15.5 1 9.5 0.4 3.4 2 1 0 2 2 2 0 RING-type zinc-finger DUF2568 PF10823.8 EKX40048.1 - 0.041 14.2 0.7 0.081 13.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2568) DNA_pol_phi PF04931.13 EKX40049.1 - 0.0025 16.0 47.1 0.0039 15.4 47.1 1.3 1 0 0 1 1 1 1 DNA polymerase phi RR_TM4-6 PF06459.12 EKX40049.1 - 0.0051 16.7 12.1 0.0055 16.6 12.1 1.0 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Mpp10 PF04006.12 EKX40049.1 - 0.0067 14.9 33.2 0.0072 14.8 33.2 1.0 1 0 0 1 1 1 1 Mpp10 protein Nop14 PF04147.12 EKX40049.1 - 0.011 14.0 41.4 0.012 13.9 41.4 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EKX40049.1 - 0.043 12.1 31.5 0.055 11.8 31.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Connexin PF00029.19 EKX40049.1 - 0.086 12.6 5.7 0.11 12.2 5.7 1.2 1 0 0 1 1 1 0 Connexin DUF3292 PF11696.8 EKX40049.1 - 0.16 10.3 5.8 0.19 10.1 5.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Utp14 PF04615.13 EKX40049.1 - 0.18 10.3 33.4 0.23 10.0 33.4 1.0 1 0 0 1 1 1 0 Utp14 protein SDA1 PF05285.12 EKX40049.1 - 0.2 11.1 43.7 0.23 10.9 43.7 1.1 1 0 0 1 1 1 0 SDA1 SpoIIIAH PF12685.7 EKX40049.1 - 0.22 11.4 13.7 0.25 11.2 13.7 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein RNA_pol_Rpc4 PF05132.14 EKX40049.1 - 0.28 11.6 12.5 0.38 11.2 12.5 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 NPR3 PF03666.13 EKX40049.1 - 0.35 9.6 16.1 0.43 9.3 16.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Tim54 PF11711.8 EKX40049.1 - 0.53 9.0 13.6 0.68 8.7 13.6 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RNA_polI_A34 PF08208.11 EKX40049.1 - 0.57 10.2 21.3 0.67 10.0 21.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 MDM1 PF15501.6 EKX40049.1 - 1.1 8.4 15.0 1.2 8.2 15.0 1.0 1 0 0 1 1 1 0 Nuclear protein MDM1 Merozoite_SPAM PF07133.11 EKX40049.1 - 1.1 9.3 50.3 1.3 9.0 50.3 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SAPS PF04499.15 EKX40049.1 - 1.7 7.3 17.9 1.8 7.3 17.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 EKX40049.1 - 1.9 7.4 13.0 2.4 7.0 13.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SpoIIP PF07454.11 EKX40049.1 - 2 7.8 13.4 2.6 7.4 13.4 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DDRGK PF09756.9 EKX40049.1 - 2 8.0 22.8 2.5 7.7 22.8 1.1 1 0 0 1 1 1 0 DDRGK domain BUD22 PF09073.10 EKX40049.1 - 2 7.6 37.1 2.2 7.5 37.1 1.0 1 0 0 1 1 1 0 BUD22 CDC27 PF09507.10 EKX40049.1 - 2.5 7.4 27.0 3.7 6.8 27.0 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SLC12 PF03522.15 EKX40049.1 - 3 6.8 8.2 3.2 6.7 8.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 PDCD2_C PF04194.13 EKX40049.1 - 3.2 7.8 18.7 3.7 7.6 18.7 1.1 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain Presenilin PF01080.17 EKX40049.1 - 4 6.1 12.6 4.4 6.0 12.6 1.0 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 EKX40049.1 - 4.8 5.0 13.5 5.7 4.7 13.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM60A PF15396.6 EKX40049.1 - 5.8 6.9 7.9 8.2 6.4 7.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Zip PF02535.22 EKX40049.1 - 7.9 5.6 11.0 9.4 5.3 11.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Orf78 PF06024.12 EKX40049.1 - 9.4 6.6 8.3 58 4.1 8.3 1.9 1 1 0 1 1 1 0 Orf78 (ac78) WW PF00397.26 EKX40052.1 - 2.1e-08 34.1 1.3 4.9e-08 32.9 1.3 1.6 1 0 0 1 1 1 1 WW domain Alpha_L_fucos PF01120.17 EKX40053.1 - 5e-87 292.6 1.9 6.2e-87 292.3 1.9 1.0 1 0 0 1 1 1 1 Alpha-L-fucosidase GHL6 PF14871.6 EKX40053.1 - 0.00022 21.4 0.0 0.0019 18.4 0.0 2.1 1 1 0 1 1 1 1 Hypothetical glycosyl hydrolase 6 cNMP_binding PF00027.29 EKX40054.1 - 7.2e-10 38.8 0.1 6.8e-09 35.7 0.1 2.2 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain DUF1411 PF07199.11 EKX40054.1 - 0.037 13.7 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) TFIIB PF00382.19 EKX40055.1 - 3.9e-13 49.2 0.4 3.5e-12 46.2 0.1 2.2 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C PF02984.19 EKX40055.1 - 9.9e-06 25.6 0.6 5.8e-05 23.2 0.1 2.2 1 1 1 2 2 2 1 Cyclin, C-terminal domain TF_Zn_Ribbon PF08271.12 EKX40055.1 - 0.00083 18.8 1.4 0.0017 17.8 1.4 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 EKX40055.1 - 0.038 13.7 0.3 1.9 8.2 0.1 2.3 1 1 1 2 2 2 0 Cyclin, N-terminal domain HTH_Mga PF08280.11 EKX40055.1 - 0.087 12.9 0.2 0.21 11.7 0.2 1.6 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain PHD PF00628.29 EKX40055.1 - 0.09 12.7 2.4 0.2 11.6 2.4 1.5 1 0 0 1 1 1 0 PHD-finger KORA PF16509.5 EKX40055.1 - 0.16 12.3 0.0 12 6.2 0.0 2.5 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor zf-RRPl_C4 PF17026.5 EKX40055.1 - 1.1 9.4 5.7 0.2 11.8 1.6 1.9 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type DUF3384 PF11864.8 EKX40056.1 - 9.3e-40 136.9 7.1 9.3e-40 136.9 7.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 EKX40056.1 - 7.3e-34 116.9 0.0 1.2e-33 116.2 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP HEAT_2 PF13646.6 EKX40057.1 - 5.2e-09 36.4 9.1 1.7e-05 25.1 0.6 2.7 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 EKX40057.1 - 0.001 19.1 2.6 4.8 7.7 0.0 4.3 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 EKX40057.1 - 0.084 13.4 2.1 2.6 8.6 0.2 3.0 3 0 0 3 3 3 0 HEAT-like repeat Tub PF01167.18 EKX40058.1 - 1.7e-21 77.1 0.0 2.8e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Tub family Atg14 PF10186.9 EKX40059.1 - 1.3e-05 24.4 1.5 0.00013 21.2 0.0 2.0 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 zf-RING_14 PF17978.1 EKX40060.1 - 1.3e-07 32.0 1.1 3e-07 30.8 1.1 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain DEAD PF00270.29 EKX40062.1 - 3.6e-32 111.5 0.2 5.2e-32 111.0 0.2 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX40062.1 - 1.9e-15 57.2 0.0 4.2e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX40062.1 - 5.5e-05 23.2 0.0 9.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EKX40062.1 - 0.097 13.0 0.2 0.2 12.0 0.2 1.6 1 1 0 1 1 1 0 AAA domain NOA36 PF06524.12 EKX40062.1 - 4.3 6.6 8.0 6.6 6.0 8.0 1.2 1 0 0 1 1 1 0 NOA36 protein Trypsin_2 PF13365.6 EKX40063.1 - 6.4e-15 56.4 0.0 1.5e-14 55.2 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Ank_2 PF12796.7 EKX40063.1 - 1.5e-14 54.3 0.0 6.9e-08 33.0 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX40063.1 - 1.8e-09 38.0 0.0 2.2e-07 31.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) PDZ_6 PF17820.1 EKX40063.1 - 1.9e-08 34.0 0.2 4.1e-08 33.0 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX40063.1 - 1e-07 32.2 0.1 2.9e-07 30.7 0.1 1.8 1 0 0 1 1 1 1 PDZ domain Ank_5 PF13857.6 EKX40063.1 - 2e-06 28.0 0.2 7.3e-05 23.0 0.0 2.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX40063.1 - 3.9e-06 27.1 0.0 0.75 10.4 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat PDZ PF00595.24 EKX40063.1 - 3.1e-05 24.2 0.0 9.6e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 PDZ domain Ank_3 PF13606.6 EKX40063.1 - 0.00012 22.2 0.1 2.6 8.9 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Tricorn_PDZ PF14685.6 EKX40063.1 - 0.048 13.6 0.1 0.21 11.6 0.0 2.1 2 0 0 2 2 2 0 Tricorn protease PDZ domain Pneumo_ncap PF03246.13 EKX40064.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Pneumovirus nucleocapsid protein TPR_2 PF07719.17 EKX40065.1 - 2.3e-05 24.1 0.0 0.0045 17.0 0.1 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX40065.1 - 0.00054 20.2 0.1 1.7 9.0 0.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX40065.1 - 0.00056 19.6 0.1 0.0027 17.5 0.1 2.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX40065.1 - 0.035 14.0 0.1 24 5.0 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX40065.1 - 0.15 12.3 0.1 0.79 10.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Prominin PF05478.11 EKX40066.1 - 3.2e-05 22.1 0.6 3.9e-05 21.9 0.6 1.1 1 0 0 1 1 1 1 Prominin adh_short PF00106.25 EKX40067.1 - 1.4e-40 138.9 0.0 1.8e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EKX40067.1 - 2.3e-29 102.6 0.0 3.2e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX40067.1 - 2.5e-05 24.3 0.0 4.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 KR domain B12D PF06522.11 EKX40067.1 - 2.1 8.2 4.5 25 4.8 0.3 3.1 3 0 0 3 3 3 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Amidase PF01425.21 EKX40068.1 - 1.6e-79 268.0 5.8 1.8e-76 258.0 5.8 2.1 1 1 0 1 1 1 1 Amidase SET PF00856.28 EKX40069.1 - 4.3e-11 43.5 0.1 1e-10 42.3 0.1 1.7 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 EKX40069.1 - 8.6e-09 35.3 11.9 8.6e-09 35.3 11.9 2.1 2 0 0 2 2 2 1 MYND finger TPR_12 PF13424.6 EKX40069.1 - 0.0012 19.1 0.0 0.0034 17.7 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TRCF PF03461.15 EKX40069.1 - 0.084 13.3 0.0 0.27 11.7 0.0 1.8 1 1 1 2 2 2 0 TRCF domain HABP4_PAI-RBP1 PF04774.15 EKX40070.1 - 0.079 13.8 5.5 0.22 12.4 5.5 1.8 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family SPRY PF00622.28 EKX40071.1 - 1.2e-14 54.4 0.0 1e-06 28.9 0.0 2.3 2 0 0 2 2 2 2 SPRY domain Neuralized PF07177.12 EKX40071.1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Neuralized RR_TM4-6 PF06459.12 EKX40071.1 - 1.2 8.9 16.9 0.4 10.5 1.7 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 PRP21_like_P PF12230.8 EKX40071.1 - 2.6 7.9 15.2 0.46 10.3 3.0 2.4 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein ExbD PF02472.16 EKX40073.1 - 2.6 8.2 5.3 18 5.5 0.3 3.0 3 1 1 4 4 4 0 Biopolymer transport protein ExbD/TolR SET PF00856.28 EKX40074.1 - 0.026 14.9 0.0 0.17 12.2 0.0 2.1 1 1 0 1 1 1 0 SET domain Ank_5 PF13857.6 EKX40075.1 - 0.021 15.1 0.1 0.044 14.1 0.1 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) MAP65_ASE1 PF03999.12 EKX40075.1 - 2.2 6.9 11.3 3.9 6.0 11.3 1.4 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Pkinase PF00069.25 EKX40076.1 - 2.2e-38 132.1 0.0 6e-37 127.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX40076.1 - 6.8e-25 87.8 0.0 9e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX40076.1 - 0.0089 16.0 0.0 0.017 15.0 0.0 1.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EKX40076.1 - 0.019 14.3 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Phycobilisome PF00502.19 EKX40077.1 - 3.9e-25 88.6 0.0 4.3e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 Phycobilisome protein ADH_zinc_N PF00107.26 EKX40078.1 - 3.8e-23 81.9 0.0 8.3e-23 80.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EKX40078.1 - 4.4e-20 71.6 3.4 4.6e-20 71.5 1.9 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EKX40078.1 - 0.011 16.8 0.0 0.018 16.1 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase zf-UDP PF14569.6 EKX40078.1 - 0.05 13.7 0.3 0.15 12.2 0.3 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger Glu_dehyd_C PF16912.5 EKX40078.1 - 0.14 11.6 0.0 1.3 8.5 0.0 2.1 1 1 0 1 1 1 0 Glucose dehydrogenase C-terminus TolA_bind_tri PF16331.5 EKX40079.1 - 0.02 15.0 2.7 0.02 15.0 2.7 3.0 3 1 0 3 3 3 0 TolA binding protein trimerisation LPP PF04728.13 EKX40079.1 - 3.8 8.0 16.6 6.3 7.3 0.5 4.8 4 1 1 5 5 5 0 Lipoprotein leucine-zipper DNA_pol_D_N PF18018.1 EKX40080.1 - 3.7 7.6 6.3 16 5.6 6.3 2.1 1 1 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain Methyltransf_11 PF08241.12 EKX40081.1 - 4.1e-12 46.6 0.0 6.9e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX40081.1 - 3.1e-07 31.0 0.0 8.9e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX40081.1 - 5.1e-06 27.1 0.0 9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX40081.1 - 2.2e-05 23.9 0.0 2.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EKX40081.1 - 2.6e-05 24.1 0.0 3.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EKX40081.1 - 2.8e-05 23.8 0.0 4.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.6 EKX40081.1 - 3.8e-05 23.5 0.0 5.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 EKX40081.1 - 0.13 11.9 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 DNA methylase DREV PF05219.12 EKX40081.1 - 0.15 11.1 0.1 0.22 10.6 0.1 1.4 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_29 PF03141.16 EKX40081.1 - 0.16 10.5 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MORN PF02493.20 EKX40082.1 - 5.3e-37 123.5 45.0 2.9e-07 30.0 1.7 7.4 7 1 0 7 7 7 7 MORN repeat Tudor_2 PF18104.1 EKX40082.1 - 0.061 13.0 10.2 0.15 11.7 0.0 4.2 5 0 0 5 5 5 0 Jumonji domain-containing protein 2A Tudor domain MORN_2 PF07661.13 EKX40082.1 - 0.55 10.6 9.6 31 5.2 0.1 5.5 6 0 0 6 6 6 0 MORN repeat variant EF-hand_1 PF00036.32 EKX40083.1 - 3.8e-25 85.5 9.4 1.2e-09 37.0 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EKX40083.1 - 5.4e-22 75.8 8.3 4.5e-08 32.4 0.1 4.7 3 1 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 EKX40083.1 - 6.8e-21 74.5 8.1 1.6e-10 41.3 1.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EKX40083.1 - 1.1e-17 63.6 16.1 7.8e-07 28.9 0.0 4.3 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EKX40083.1 - 4.6e-14 51.2 12.2 9e-06 25.0 0.6 4.6 5 0 0 5 5 5 3 EF hand EF-hand_4 PF12763.7 EKX40083.1 - 0.0048 16.8 5.0 4.2 7.4 0.4 3.5 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 EKX40083.1 - 0.0095 15.8 8.0 1.1 9.2 0.1 3.9 3 1 1 4 4 4 2 EF hand DUF3037 PF11236.8 EKX40083.1 - 0.019 15.4 0.0 0.1 13.0 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) Caleosin PF05042.13 EKX40083.1 - 0.034 14.1 0.7 2 8.3 0.0 2.6 1 1 2 3 3 3 0 Caleosin related protein DUF3349 PF11829.8 EKX40083.1 - 0.052 14.3 0.7 0.53 11.1 0.3 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3349) HAT PF02184.16 EKX40083.1 - 0.079 12.9 5.8 0.32 11.0 0.4 2.5 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat CwfJ_C_1 PF04677.15 EKX40083.1 - 0.11 12.4 0.2 0.2 11.5 0.1 1.5 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 PSDC PF12588.8 EKX40084.1 - 0.018 15.0 0.0 0.042 13.8 0.0 1.6 1 1 0 1 1 1 0 Phophatidylserine decarboxylase zf-BED PF02892.15 EKX40084.1 - 0.023 14.7 1.4 0.041 13.9 0.7 1.8 2 0 0 2 2 2 0 BED zinc finger Spc7_C2 PF15577.6 EKX40084.1 - 0.074 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Spc7_C2 AMP-binding PF00501.28 EKX40085.1 - 5.5e-79 265.7 0.0 4.1e-78 262.8 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EKX40085.1 - 6.6e-05 23.8 0.0 0.00016 22.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PhoLip_ATPase_C PF16212.5 EKX40086.1 - 2.4e-56 191.3 16.0 2.4e-56 191.3 16.0 2.8 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EKX40086.1 - 1.8e-16 59.5 3.1 1.8e-16 59.5 3.1 2.0 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 EKX40086.1 - 3e-11 43.2 1.6 1.7e-10 40.7 0.0 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EKX40086.1 - 1e-09 39.0 0.2 5.7e-06 26.8 0.2 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EKX40086.1 - 4.3e-06 26.7 0.0 2e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EKX40086.1 - 0.035 13.9 0.3 0.29 10.8 0.2 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase FDC-SP PF15215.6 EKX40086.1 - 4 8.0 5.3 1.4 9.5 1.1 2.3 3 0 0 3 3 3 0 Follicular dendritic cell secreted peptide zf-RING_2 PF13639.6 EKX40087.1 - 2.6e-11 43.7 9.2 4.8e-11 42.8 9.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EKX40087.1 - 6.7e-08 32.7 5.8 1.8e-07 31.3 5.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EKX40087.1 - 1.5e-06 28.0 9.5 2.9e-06 27.0 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX40087.1 - 3.2e-06 27.0 8.6 5.4e-06 26.3 8.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EKX40087.1 - 6.6e-06 25.9 6.5 1.1e-05 25.2 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX40087.1 - 8.8e-06 25.5 8.4 1.6e-05 24.6 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EKX40087.1 - 1.7e-05 24.4 6.5 1.7e-05 24.4 6.5 1.7 2 0 0 2 2 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EKX40087.1 - 2.2e-05 24.4 5.3 4.7e-05 23.3 5.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EKX40087.1 - 0.00023 21.1 3.7 0.00052 20.0 3.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EKX40087.1 - 0.0067 16.3 7.5 0.013 15.3 7.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 RINGv PF12906.7 EKX40087.1 - 0.14 12.3 8.2 0.28 11.3 8.2 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING_10 PF16685.5 EKX40087.1 - 0.22 11.7 5.9 0.39 10.9 5.9 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 Zn_ribbon_17 PF17120.5 EKX40087.1 - 0.23 11.1 7.9 0.44 10.2 7.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type SurA_N_2 PF13623.6 EKX40087.1 - 0.33 10.8 1.0 0.61 9.9 1.0 1.3 1 0 0 1 1 1 0 SurA N-terminal domain ATP-synt_DE PF00401.20 EKX40087.1 - 0.72 10.2 4.2 4.7 7.6 0.6 2.5 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain DUF1272 PF06906.11 EKX40087.1 - 1.2 9.3 5.0 3.6 7.8 5.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_4 PF14570.6 EKX40087.1 - 1.3 8.9 9.5 25 4.7 9.5 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 EKX40087.1 - 3.1 7.9 7.5 5.5 7.1 7.5 1.4 1 0 0 1 1 1 0 Zinc-finger DNA_photolyase PF00875.18 EKX40090.1 - 1e-15 58.1 0.0 1.9e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase PsbP PF01789.16 EKX40091.1 - 0.00051 20.2 0.0 0.00084 19.5 0.0 1.4 1 0 0 1 1 1 1 PsbP UQ_con PF00179.26 EKX40092.1 - 1.8e-42 144.3 0.0 2.1e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EKX40092.1 - 7.7e-05 22.4 0.0 0.0002 21.1 0.0 1.6 1 1 1 2 2 2 1 Prokaryotic E2 family B RWD PF05773.22 EKX40092.1 - 0.022 15.0 0.2 0.03 14.6 0.2 1.5 1 1 0 1 1 1 0 RWD domain UEV PF05743.13 EKX40092.1 - 0.038 13.9 0.1 0.071 13.0 0.1 1.5 1 1 0 1 1 1 0 UEV domain FAD_binding_4 PF01565.23 EKX40094.1 - 2.3e-14 53.3 0.0 6.9e-14 51.8 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Cupin_4 PF08007.12 EKX40095.1 - 2.5e-20 73.2 0.1 8.3e-18 64.9 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein Cupin_8 PF13621.6 EKX40095.1 - 3.8e-05 23.5 0.1 0.0002 21.2 0.1 2.0 1 1 0 1 1 1 1 Cupin-like domain Cupin_1 PF00190.22 EKX40095.1 - 0.027 14.1 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 Cupin Cupin_2 PF07883.11 EKX40095.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Cupin domain SdpI PF13630.6 EKX40096.1 - 0.0068 16.5 5.2 0.051 13.7 2.0 2.3 1 1 1 2 2 2 2 SdpI/YhfL protein family YtzH PF14165.6 EKX40097.1 - 0.037 14.4 1.4 0.058 13.8 0.4 1.8 1 1 1 2 2 2 0 YtzH-like protein DivIVA PF05103.13 EKX40097.1 - 0.13 12.4 2.6 4.4 7.4 0.2 2.3 1 1 1 2 2 2 0 DivIVA protein TPR_1 PF00515.28 EKX40098.1 - 0.00011 21.9 8.6 0.0081 15.9 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX40098.1 - 0.00017 21.8 9.0 0.00034 20.8 0.5 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX40098.1 - 0.0097 16.0 12.5 0.04 14.0 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX40098.1 - 0.052 13.4 3.6 0.59 10.1 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX40098.1 - 0.31 11.4 9.6 0.82 10.0 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat POX PF07526.11 EKX40098.1 - 0.91 10.1 7.8 0.1 13.1 2.6 2.1 3 0 0 3 3 3 0 Associated with HOX Glyco_transf_92 PF01697.27 EKX40100.1 - 5.7e-12 45.8 0.0 1.4e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 92 HtrL_YibB PF09612.10 EKX40100.1 - 1.6e-07 31.1 0.7 6.3e-07 29.2 0.8 1.7 1 1 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) Glyco_tranf_2_4 PF13704.6 EKX40100.1 - 1.7e-05 25.3 0.0 4.5e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 GRIM-19 PF06212.12 EKX40100.1 - 0.85 9.6 4.0 0.42 10.5 1.4 1.8 2 0 0 2 2 2 0 GRIM-19 protein Ald_Xan_dh_C2 PF02738.18 EKX40101.1 - 2e-205 683.4 2.9 2.9e-205 682.9 2.9 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 EKX40101.1 - 2e-45 154.6 0.0 4.7e-45 153.4 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 EKX40101.1 - 4.4e-31 106.7 0.1 3.6e-30 103.8 0.0 2.6 3 0 0 3 3 3 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 EKX40101.1 - 1.3e-28 99.2 0.0 5.4e-28 97.2 0.0 2.1 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 EKX40101.1 - 6.3e-28 97.3 0.0 1.2e-27 96.4 0.0 1.5 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.27 EKX40101.1 - 9.1e-08 32.0 0.9 1.1e-06 28.5 0.2 2.9 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.9 EKX40101.1 - 0.029 14.2 0.7 0.13 12.1 0.7 2.1 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Glyco_transf_92 PF01697.27 EKX40102.1 - 7.1e-12 45.5 0.0 1.7e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 92 HtrL_YibB PF09612.10 EKX40102.1 - 4.4e-08 33.0 0.1 1.6e-07 31.1 0.1 1.9 1 1 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) Glyco_tranf_2_4 PF13704.6 EKX40102.1 - 1.7e-05 25.3 0.0 4.5e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 GRIM-19 PF06212.12 EKX40102.1 - 0.22 11.5 1.2 0.37 10.7 1.2 1.4 1 0 0 1 1 1 0 GRIM-19 protein NinF PF05810.12 EKX40103.1 - 0.0099 15.7 0.4 0.0099 15.7 0.4 2.1 2 0 0 2 2 2 1 NinF protein UME PF08064.13 EKX40103.1 - 0.047 13.6 0.6 0.11 12.5 0.1 1.8 2 0 0 2 2 2 0 UME (NUC010) domain Eapp_C PF10238.9 EKX40103.1 - 2.2 8.3 11.3 0.64 10.1 2.8 2.5 2 0 0 2 2 2 0 E2F-associated phosphoprotein DnaG_DnaB_bind PF08278.11 EKX40103.1 - 3.2 8.4 17.5 0.23 12.1 11.7 2.0 1 1 1 2 2 2 0 DNA primase DnaG DnaB-binding DIT1_PvcA PF05141.12 EKX40103.1 - 7.7 5.9 9.4 0.86 9.0 4.0 1.8 1 1 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein CAP_N PF01213.19 EKX40104.1 - 1.3 8.4 4.2 1.8 8.0 4.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF2304 PF10066.9 EKX40105.1 - 2.3 8.5 8.8 4.2 7.6 1.5 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) DUF2070 PF09843.9 EKX40105.1 - 2.7 6.2 10.9 4.3 5.5 10.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Lactamase_B_2 PF12706.7 EKX40106.1 - 1.8e-07 30.9 0.0 0.0082 15.7 0.0 2.8 3 0 0 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 EKX40106.1 - 1.4e-06 27.9 0.0 3e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 EKX40106.1 - 0.019 15.0 0.2 0.15 12.0 0.1 2.3 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily RWP-RK PF02042.15 EKX40108.1 - 3.2e-12 46.2 0.0 4.8e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX40108.1 - 0.0084 15.9 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family RWP-RK PF02042.15 EKX40109.1 - 3.2e-12 46.2 0.0 4.8e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX40109.1 - 0.0085 15.9 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family RWP-RK PF02042.15 EKX40110.1 - 3.2e-12 46.2 0.0 4.8e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX40110.1 - 0.0085 15.9 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory protein, Fis family PSS PF03034.15 EKX40112.1 - 1.3e-96 323.6 11.9 1.7e-96 323.2 11.9 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase RRM_1 PF00076.22 EKX40113.1 - 1.5e-10 40.8 0.1 0.00013 21.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DMRL_synthase PF00885.19 EKX40114.1 - 1.6e-49 167.4 0.1 3.5e-49 166.2 0.2 1.5 2 0 0 2 2 2 1 6,7-dimethyl-8-ribityllumazine synthase ICL PF00463.21 EKX40115.1 - 3.7e-171 570.2 0.1 5.9e-171 569.5 0.1 1.3 1 1 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EKX40115.1 - 2.3e-12 46.9 0.0 3.7e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase RVT_thumb PF06817.14 EKX40115.1 - 0.055 13.3 0.0 0.28 11.1 0.0 2.1 3 0 0 3 3 3 0 Reverse transcriptase thumb domain Kinesin PF00225.23 EKX40116.1 - 9.6e-95 317.3 0.2 3.6e-51 174.1 0.0 2.3 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 EKX40116.1 - 7.6e-21 74.6 1.6 2.2e-19 69.8 0.2 3.2 2 1 0 2 2 2 1 Microtubule binding Kinesin_assoc PF16183.5 EKX40116.1 - 1.8e-06 28.2 17.6 6e-05 23.3 7.2 4.0 3 1 1 4 4 4 2 Kinesin-associated KIF1B PF12423.8 EKX40116.1 - 9.9e-06 25.9 0.1 4.2e-05 23.9 0.1 2.1 1 0 0 1 1 1 1 Kinesin protein 1B Herpes_BLRF2 PF05812.12 EKX40116.1 - 0.00014 22.0 1.8 0.00038 20.6 1.8 1.7 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein FHA PF00498.26 EKX40116.1 - 0.18 12.2 0.1 0.37 11.2 0.1 1.6 1 0 0 1 1 1 0 FHA domain Mitofilin PF09731.9 EKX40116.1 - 4.5 6.0 13.8 8.1 5.1 13.8 1.4 1 1 0 1 1 1 0 Mitochondrial inner membrane protein DUF2203 PF09969.9 EKX40117.1 - 1.6 9.5 15.9 3.7 8.3 0.6 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) V_ATPase_I PF01496.19 EKX40117.1 - 2.6 5.8 10.6 2.8 5.7 10.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fzo_mitofusin PF04799.13 EKX40117.1 - 3.9 7.0 8.5 0.3 10.6 0.2 2.8 3 1 0 3 3 3 0 fzo-like conserved region DUF1704 PF08014.11 EKX40119.1 - 3.7e-05 22.9 3.0 4.5e-05 22.6 3.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1704) TipAS PF07739.13 EKX40119.1 - 1.1 9.8 9.9 6.9 7.2 1.3 2.5 1 1 2 3 3 3 0 TipAS antibiotic-recognition domain Myb_DNA-binding PF00249.31 EKX40120.1 - 4.2e-30 103.7 2.8 4e-12 46.1 0.2 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX40120.1 - 7.8e-10 38.9 4.5 0.00015 22.0 0.1 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain GerE PF00196.19 EKX40120.1 - 0.068 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family CCDC-167 PF15188.6 EKX40121.1 - 0.038 14.3 1.2 0.038 14.3 1.2 4.5 3 2 1 4 4 4 0 Coiled-coil domain-containing protein 167 3-PAP PF12578.8 EKX40121.1 - 0.13 12.0 4.7 0.59 9.9 0.1 3.3 2 2 2 4 4 4 0 Myotubularin-associated protein TPD52 PF04201.15 EKX40121.1 - 5.2 6.7 14.6 0.44 10.1 0.2 3.6 3 1 0 3 3 3 0 Tumour protein D52 family FH2 PF02181.23 EKX40122.1 - 2.2e-40 138.9 1.6 1.3e-33 116.6 0.5 2.5 1 1 1 2 2 2 2 Formin Homology 2 Domain FHA PF00498.26 EKX40122.1 - 9.1e-18 64.4 0.2 1.9e-17 63.4 0.2 1.6 1 0 0 1 1 1 1 FHA domain PH PF00169.29 EKX40122.1 - 2.2e-16 60.2 0.5 6.7e-16 58.7 0.5 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EKX40122.1 - 6.8e-08 32.9 0.7 2.7e-07 31.0 0.7 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain Yop-YscD_cpl PF16697.5 EKX40122.1 - 6.6e-07 29.6 0.0 1.7e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Drf_GBD PF06371.13 EKX40122.1 - 1.5e-05 24.7 0.0 7.2e-05 22.4 0.0 2.0 1 1 1 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EKX40122.1 - 1.7e-05 24.5 0.2 4.1e-05 23.3 0.2 1.6 1 0 0 1 1 1 1 Diaphanous FH3 Domain PH_9 PF15410.6 EKX40122.1 - 0.0057 17.0 0.2 0.024 15.0 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Mus7 PF09462.10 EKX40122.1 - 0.065 12.1 0.0 0.097 11.5 0.0 1.1 1 0 0 1 1 1 0 Mus7/MMS22 family DUF3010 PF11215.8 EKX40122.1 - 0.17 12.2 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3010) Beta_helix PF13229.6 EKX40123.1 - 1e-27 97.0 19.8 1.4e-17 64.0 9.7 2.6 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 EKX40123.1 - 1e-13 51.1 6.3 1e-12 47.9 6.6 2.1 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) NAGLU_N PF12971.7 EKX40123.1 - 0.042 13.6 0.2 3.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain DUF4957 PF16318.5 EKX40123.1 - 0.063 13.2 1.8 0.21 11.5 1.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4957) Adeno_PIX PF03955.14 EKX40124.1 - 1.3 9.2 6.1 3 8.1 3.0 2.6 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) TMEM154 PF15102.6 EKX40124.1 - 4.4 7.2 9.5 16 5.4 0.1 2.3 2 0 0 2 2 2 0 TMEM154 protein family Fzo_mitofusin PF04799.13 EKX40126.1 - 0.016 14.8 1.5 0.016 14.8 1.5 2.1 2 0 0 2 2 2 0 fzo-like conserved region Hemocyanin_M PF00372.19 EKX40126.1 - 0.024 13.9 0.3 0.095 11.9 0.2 1.9 1 1 1 2 2 2 0 Hemocyanin, copper containing domain Latarcin PF10279.9 EKX40126.1 - 0.045 14.1 0.8 6.2 7.3 2.0 3.0 2 1 0 2 2 2 0 Latarcin precursor Carb_anhydrase PF00194.21 EKX40128.1 - 1.5e-16 60.7 0.0 2.2e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF1647 PF07801.11 EKX40129.1 - 2.5e-11 43.5 0.0 4.4e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) Met_10 PF02475.16 EKX40129.1 - 0.0036 17.1 0.0 0.0085 15.9 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein RrnaAD PF00398.20 EKX40129.1 - 0.007 15.5 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 EKX40129.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 EKX40129.1 - 0.085 13.6 0.0 0.25 12.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EKX40129.1 - 0.099 12.5 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EKX40129.1 - 0.2 11.2 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ank PF00023.30 EKX40130.1 - 1.7e-12 47.2 0.2 2.8e-05 24.4 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EKX40130.1 - 3.4e-12 46.8 0.0 8.6e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX40130.1 - 1.1e-11 45.0 0.2 9e-11 42.1 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX40130.1 - 4.4e-09 36.4 0.5 1.8e-06 28.1 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX40130.1 - 4.9e-07 29.5 1.0 0.00031 20.9 0.1 3.0 2 1 0 2 2 2 2 Ankyrin repeat DUF4614 PF15391.6 EKX40130.1 - 1.6e-05 25.0 4.2 1.6e-05 25.0 4.2 3.9 3 1 0 4 4 4 1 Domain of unknown function (DUF4614) Nmad5 PF18757.1 EKX40130.1 - 7.8 6.6 10.5 1.9 8.6 3.6 2.9 3 0 0 3 3 3 0 Nucleotide modification associated domain 5 WD40 PF00400.32 EKX40131.1 - 1.9e-10 41.1 9.3 0.00036 21.3 0.1 4.4 4 1 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX40131.1 - 0.00032 21.0 0.0 0.011 16.0 0.0 2.6 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX40131.1 - 0.079 11.9 0.0 0.24 10.3 0.0 1.9 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MaoC_dehydratas PF01575.19 EKX40132.1 - 0.024 14.2 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 MaoC like domain Rpr2 PF04032.16 EKX40134.1 - 0.09 13.1 0.7 0.09 13.1 0.7 1.9 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-CSL PF05207.13 EKX40134.1 - 0.85 9.4 8.2 21 4.9 8.2 2.2 1 1 0 1 1 1 0 CSL zinc finger IBN_N PF03810.19 EKX40135.1 - 3.9e-11 42.7 0.0 5.3e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain SulA PF03846.14 EKX40135.1 - 0.008 16.1 0.0 0.011 15.6 0.0 1.3 1 1 0 1 1 1 1 Cell division inhibitor SulA Xpo1 PF08389.12 EKX40135.1 - 0.023 14.7 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 Exportin 1-like protein Maf PF02545.14 EKX40137.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 2 0 0 2 2 2 0 Maf-like protein Sporozoite_P67 PF05642.11 EKX40139.1 - 0.06 11.4 3.3 0.073 11.2 3.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 EKX40139.1 - 3 6.0 11.7 3.6 5.7 11.7 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 EKX40139.1 - 7.2 5.8 10.2 9.9 5.4 10.2 1.2 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.11 EKX40141.1 - 0.06 11.4 3.3 0.073 11.2 3.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 EKX40141.1 - 3 6.0 11.7 3.6 5.7 11.7 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 EKX40141.1 - 7.2 5.8 10.2 9.9 5.4 10.2 1.2 1 0 0 1 1 1 0 NOA36 protein Dicty_REP PF05086.12 EKX40142.1 - 0.33 8.9 1.0 0.33 8.9 1.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PBP1_TM PF14812.6 EKX40142.1 - 4.4 7.7 10.9 12 6.3 10.9 1.8 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sporozoite_P67 PF05642.11 EKX40144.1 - 0.06 11.4 3.3 0.073 11.2 3.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 EKX40144.1 - 3 6.0 11.7 3.6 5.7 11.7 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 EKX40144.1 - 7.2 5.8 10.2 9.9 5.4 10.2 1.2 1 0 0 1 1 1 0 NOA36 protein Dicty_REP PF05086.12 EKX40145.1 - 0.3 9.0 0.9 0.3 9.0 0.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein PBP1_TM PF14812.6 EKX40145.1 - 4.4 7.7 10.9 12 6.3 10.9 1.8 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal cNMP_binding PF00027.29 EKX40146.1 - 0.00048 20.2 0.0 0.045 13.8 0.0 2.1 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain cNMP_binding PF00027.29 EKX40147.1 - 3.5e-10 39.8 0.0 6.1e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ank_4 PF13637.6 EKX40149.1 - 2.2e-13 50.4 0.0 9.6e-08 32.4 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX40149.1 - 1.1e-11 45.2 0.0 2.2e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX40149.1 - 3.5e-11 43.0 0.1 0.00013 22.3 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EKX40149.1 - 3.2e-10 40.0 0.2 0.00025 21.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX40149.1 - 4.9e-07 29.6 0.0 0.025 15.1 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat DUF1515 PF07439.11 EKX40149.1 - 0.3 11.1 0.7 0.67 10.0 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Trp_syntA PF00290.20 EKX40150.1 - 1.2e-85 286.5 0.0 1.8e-85 285.9 0.0 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 EKX40150.1 - 4.2e-47 161.0 0.6 8.5e-47 160.0 0.6 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.21 EKX40150.1 - 2.8e-05 23.7 0.1 6.6e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 EKX40150.1 - 0.00095 18.5 0.2 0.011 15.0 0.0 2.6 3 0 0 3 3 3 1 Thiazole biosynthesis protein ThiG DNA_pol3_theta PF06440.11 EKX40152.1 - 8.4 6.1 7.7 2.8 7.6 0.3 3.4 2 2 1 3 3 3 0 DNA polymerase III, theta subunit EMP70 PF02990.16 EKX40153.1 - 2.9e-196 653.2 1.8 2.9e-196 653.2 1.8 1.3 2 0 0 2 2 2 1 Endomembrane protein 70 RELT PF12606.8 EKX40153.1 - 3.8 6.6 0.0 3.8 6.6 0.0 4.0 4 0 0 4 4 4 0 Tumour necrosis factor receptor superfamily member 19 cNMP_binding PF00027.29 EKX40154.1 - 1e-08 35.1 0.0 0.0037 17.3 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DZR PF12773.7 EKX40155.1 - 0.00021 21.2 4.5 0.00021 21.2 4.5 1.6 2 0 0 2 2 2 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 EKX40155.1 - 0.0015 18.2 5.2 0.0071 16.0 5.1 2.2 1 1 1 2 2 2 2 zinc-ribbon domain zf-ribbon_3 PF13248.6 EKX40155.1 - 0.0019 17.6 2.4 0.0036 16.7 2.4 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DUF3824 PF12868.7 EKX40155.1 - 0.0031 18.2 5.5 0.0031 18.2 5.5 2.8 3 0 0 3 3 2 1 Domain of unknwon function (DUF3824) zinc_ribbon_15 PF17032.5 EKX40155.1 - 0.0054 17.5 3.8 0.0085 16.8 3.8 1.3 1 0 0 1 1 1 1 zinc-ribbon family Nudix_N_2 PF14803.6 EKX40155.1 - 0.026 14.4 5.1 2.2 8.2 0.1 2.5 3 0 0 3 3 2 0 Nudix N-terminal GFA PF04828.14 EKX40155.1 - 0.13 12.6 3.2 3.8 7.9 0.4 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Spt20 PF12090.8 EKX40155.1 - 0.23 11.1 18.0 3.7 7.1 15.4 2.1 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.13 EKX40155.1 - 0.25 11.3 17.2 0.4 10.6 17.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-B_box PF00643.24 EKX40155.1 - 0.39 10.9 2.2 0.58 10.4 2.2 1.2 1 0 0 1 1 1 0 B-box zinc finger SUIM_assoc PF16619.5 EKX40155.1 - 3.2 7.9 17.2 0.34 11.0 8.8 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 NOB1_Zn_bind PF08772.11 EKX40155.1 - 4.1 7.7 7.8 27 5.0 1.0 2.3 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like DSPc PF00782.20 EKX40156.1 - 4.8e-11 42.6 0.0 7.1e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Bromo_MP PF01573.16 EKX40156.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Bromovirus movement protein zf-HIT PF04438.16 EKX40157.1 - 9.2e-07 28.6 6.3 9.2e-07 28.6 6.3 2.0 2 0 0 2 2 2 1 HIT zinc finger YL1_C PF08265.11 EKX40157.1 - 0.025 14.3 1.5 0.043 13.6 1.5 1.4 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain Ribosomal_L37e PF01907.19 EKX40157.1 - 1.2 9.3 5.7 11 6.3 1.1 2.5 2 0 0 2 2 2 0 Ribosomal protein L37e OrfB_Zn_ribbon PF07282.11 EKX40157.1 - 2.3 8.2 5.7 6 6.9 0.3 2.5 2 0 0 2 2 2 0 Putative transposase DNA-binding domain AMPK1_CBM PF16561.5 EKX40159.1 - 6.7e-22 77.5 0.8 1.2e-21 76.7 0.8 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase PapC_N PF13954.6 EKX40159.1 - 0.0011 19.0 0.0 0.0023 17.9 0.0 1.5 2 0 0 2 2 2 1 PapC N-terminal domain KH_8 PF17903.1 EKX40159.1 - 0.046 13.8 0.0 0.086 12.9 0.0 1.4 1 0 0 1 1 1 0 Krr1 KH1 domain BACK PF07707.15 EKX40160.1 - 3.6e-14 52.7 4.2 1.8e-11 44.0 0.4 3.0 3 0 0 3 3 3 2 BTB And C-terminal Kelch BTB PF00651.31 EKX40160.1 - 2.4e-08 34.2 0.0 1.1e-07 32.0 0.0 2.0 1 1 0 1 1 1 1 BTB/POZ domain Pkinase_Tyr PF07714.17 EKX40161.1 - 3.1e-49 167.6 0.0 3.5e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX40161.1 - 1.6e-41 142.4 0.0 1.9e-41 142.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain EF-hand_7 PF13499.6 EKX40162.1 - 1.9e-16 60.3 2.7 4.4e-07 30.2 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX40162.1 - 9.7e-14 49.8 2.9 0.0015 18.0 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EKX40162.1 - 1e-12 46.9 3.7 0.073 13.0 0.1 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EKX40162.1 - 1.3e-09 37.8 2.9 0.002 17.9 0.1 3.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX40162.1 - 3.4e-06 26.3 2.8 0.088 12.3 0.0 4.0 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.9 EKX40162.1 - 0.0019 18.5 0.3 0.18 12.1 0.0 2.6 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF5580 PF17743.1 EKX40162.1 - 0.0093 14.6 0.3 1.4 7.3 0.1 2.1 2 0 0 2 2 2 2 Family of unknown function (DUF5580) Dockerin_1 PF00404.18 EKX40162.1 - 0.036 14.3 0.1 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 Dockerin type I domain Pkinase PF00069.25 EKX40163.1 - 4.2e-80 268.9 0.1 5.4e-80 268.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX40163.1 - 1.7e-44 152.1 0.1 2.2e-44 151.7 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX40163.1 - 3.5e-06 26.5 0.1 5.5e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EKX40163.1 - 9.8e-06 25.1 0.2 0.00026 20.4 0.0 2.7 2 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 EKX40163.1 - 7.7e-05 22.4 0.5 0.00013 21.6 0.5 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EKX40163.1 - 0.00047 20.2 0.0 0.36 10.7 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX40163.1 - 0.00071 18.5 0.1 0.00078 18.3 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EKX40163.1 - 0.0081 15.7 0.8 0.013 15.0 0.0 1.6 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL FTA2 PF13095.6 EKX40163.1 - 0.019 14.6 1.0 0.084 12.5 0.1 2.0 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Ank_4 PF13637.6 EKX40164.1 - 3.6e-09 37.0 1.5 6.3e-05 23.4 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX40164.1 - 2.4e-07 31.2 0.2 5.5e-07 30.1 0.1 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX40164.1 - 2.5e-07 30.8 0.9 0.00019 21.8 0.7 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EKX40164.1 - 0.00027 21.1 0.6 1.8 9.4 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Guanylate_cyc PF00211.20 EKX40165.1 - 4e-54 183.0 0.2 4.6e-54 182.8 0.2 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 EKX40166.1 - 1e-52 179.0 0.0 1.4e-52 178.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX40166.1 - 1.4e-46 159.0 0.0 1.9e-46 158.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EKX40166.1 - 4.2e-06 25.8 0.0 6.5e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX40166.1 - 0.00035 20.6 0.0 0.00052 20.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EKX40166.1 - 0.0012 18.5 0.1 0.002 17.8 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EKX40166.1 - 0.0076 15.6 0.1 0.017 14.4 0.1 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EKX40166.1 - 0.011 15.1 0.2 0.018 14.4 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EKX40166.1 - 0.021 13.9 0.1 0.041 12.9 0.1 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 Haspin_kinase PF12330.8 EKX40166.1 - 0.023 13.7 0.1 0.036 13.0 0.1 1.3 1 1 0 1 1 1 0 Haspin like kinase domain Glyco_transf_41 PF13844.6 EKX40167.1 - 2.3e-25 89.0 0.0 3.1e-15 55.6 0.0 3.1 2 1 1 3 3 3 3 Glycosyl transferase family 41 MazG-like PF12643.7 EKX40168.1 - 2.1e-11 43.9 0.0 3.5e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 MazG-like family MazG PF03819.17 EKX40168.1 - 4e-06 26.9 0.0 6.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain Torsin PF06309.11 EKX40169.1 - 2.3e-08 34.2 0.0 3.4e-07 30.4 0.0 2.2 2 0 0 2 2 2 1 Torsin AAA PF00004.29 EKX40169.1 - 2.8e-06 27.8 0.0 6.4e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EKX40169.1 - 6.7e-06 26.4 0.1 0.001 19.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EKX40169.1 - 0.005 17.0 0.0 0.024 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 EKX40169.1 - 0.035 14.5 0.4 0.88 10.0 0.0 2.9 3 1 0 3 3 3 0 RNA helicase AAA_16 PF13191.6 EKX40169.1 - 0.048 14.0 0.0 1.2 9.5 0.0 2.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 EKX40169.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 EKX40169.1 - 0.14 11.6 0.0 0.67 9.3 0.0 2.0 1 1 0 1 1 1 0 Bacterial TniB protein DnaJ PF00226.31 EKX40170.1 - 2.2e-10 40.5 0.1 4.2e-10 39.6 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Sigma70_ner PF04546.13 EKX40170.1 - 0.054 13.4 2.1 1.2 9.0 2.0 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region TPR_12 PF13424.6 EKX40171.1 - 6e-51 170.6 0.2 5.4e-17 61.8 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX40171.1 - 5.4e-34 115.1 1.3 4.8e-09 35.8 0.0 6.4 6 1 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 EKX40171.1 - 8.2e-23 79.2 0.0 3.8e-05 23.3 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 EKX40171.1 - 4.5e-22 76.4 1.8 2.4e-05 24.1 0.0 5.6 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 EKX40171.1 - 9.2e-20 69.1 0.2 6.4e-05 22.8 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EKX40171.1 - 3.3e-14 51.8 0.5 0.0016 18.5 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX40171.1 - 6.7e-11 42.2 3.5 5e-07 29.4 0.6 2.1 1 1 2 3 3 3 3 MalT-like TPR region TPR_11 PF13414.6 EKX40171.1 - 1.5e-10 40.6 0.4 0.0064 16.2 0.1 4.7 4 0 0 4 4 4 2 TPR repeat TPR_6 PF13174.6 EKX40171.1 - 1.4e-09 38.0 2.1 0.18 12.5 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX40171.1 - 1.1e-08 35.6 0.7 0.018 15.7 0.0 3.7 4 1 0 4 4 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX40171.1 - 2.5e-08 34.1 1.7 0.049 14.5 0.0 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX40171.1 - 1.8e-07 31.6 0.8 0.013 16.0 0.1 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat RPN7 PF10602.9 EKX40171.1 - 2.3e-07 30.7 0.2 0.021 14.6 0.0 3.1 3 0 0 3 3 3 2 26S proteasome subunit RPN7 ANAPC3 PF12895.7 EKX40171.1 - 2.2e-05 24.6 0.1 0.013 15.7 0.0 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 EKX40171.1 - 8.8e-05 22.8 0.0 1.5 9.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat PPR PF01535.20 EKX40171.1 - 0.00016 21.6 0.0 0.3 11.4 0.0 3.6 4 0 0 4 4 4 1 PPR repeat TPR_17 PF13431.6 EKX40171.1 - 0.0015 18.8 0.1 0.94 10.0 0.0 4.2 5 0 0 5 5 4 1 Tetratricopeptide repeat SNAP PF14938.6 EKX40171.1 - 0.0015 18.0 0.2 0.2 11.1 0.0 2.3 1 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_3 PF07720.12 EKX40171.1 - 0.0032 17.4 1.1 1.9 8.6 0.1 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat MIT PF04212.18 EKX40171.1 - 0.013 15.6 0.3 7.9 6.6 0.0 3.1 3 1 0 3 3 2 0 MIT (microtubule interacting and transport) domain SPO22 PF08631.10 EKX40171.1 - 0.044 13.3 0.1 0.22 11.0 0.1 2.0 2 1 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like DUF2989 PF11207.8 EKX40171.1 - 0.046 13.5 0.6 0.24 11.2 0.3 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2989) SRP68 PF16969.5 EKX40171.1 - 0.077 12.0 0.3 6.8 5.6 0.0 2.1 2 0 0 2 2 2 0 RNA-binding signal recognition particle 68 TPR_9 PF13371.6 EKX40171.1 - 0.098 12.8 0.1 9.2 6.5 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2225 PF09986.9 EKX40171.1 - 0.13 11.9 0.3 2.4 7.8 0.1 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) YqaH PF17448.2 EKX40171.1 - 0.14 12.5 0.8 1.3 9.4 0.1 2.6 2 1 2 4 4 3 0 Uncharacterized YqaH-like SQS_PSY PF00494.19 EKX40172.1 - 7.6e-69 232.1 2.2 8.6e-69 232.0 2.2 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase Ank_2 PF12796.7 EKX40173.1 - 6.7e-13 49.0 1.6 1.5e-08 35.1 1.5 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX40173.1 - 7.9e-13 48.6 1.7 1.2e-07 32.1 0.6 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX40173.1 - 3.6e-08 33.0 2.8 0.08 13.5 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EKX40173.1 - 1.5e-07 31.6 1.3 0.00011 22.5 0.3 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX40173.1 - 6e-06 26.5 3.7 0.068 13.7 0.5 3.5 3 0 0 3 3 3 2 Ankyrin repeat DUF2207 PF09972.9 EKX40173.1 - 0.019 13.8 0.2 0.035 12.9 0.2 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ribosomal_L18_c PF14204.6 EKX40173.1 - 0.046 14.7 0.5 0.11 13.4 0.5 1.6 1 0 0 1 1 1 0 Ribosomal L18 C-terminal region Wzy_C PF04932.15 EKX40173.1 - 0.13 11.9 3.4 0.33 10.6 3.4 1.7 1 0 0 1 1 1 0 O-Antigen ligase RHH_4 PF13467.6 EKX40173.1 - 0.23 11.4 1.3 14 5.7 0.1 2.5 2 0 0 2 2 2 0 Ribbon-helix-helix domain Phage_holin_3_6 PF07332.11 EKX40173.1 - 0.29 11.2 14.3 1 9.4 14.3 1.9 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III SUR7 PF06687.12 EKX40173.1 - 0.63 9.6 3.1 0.95 9.1 3.1 1.2 1 0 0 1 1 1 0 SUR7/PalI family DUF2053 PF09767.9 EKX40174.1 - 5.7e-45 153.3 6.8 6.4e-45 153.2 6.8 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2053) zf-C3HC4_3 PF13920.6 EKX40175.1 - 2.3e-06 27.4 2.9 3.7e-06 26.7 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EKX40175.1 - 6.4e-05 22.7 7.6 0.0001 22.1 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX40175.1 - 0.0058 16.6 5.6 0.0095 15.9 5.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EKX40175.1 - 0.01 15.7 6.1 0.033 14.0 6.1 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EKX40175.1 - 0.041 13.7 6.0 0.07 13.0 6.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX40175.1 - 0.089 13.1 7.2 0.14 12.5 7.2 1.3 1 0 0 1 1 1 0 Ring finger domain zf-RING_6 PF14835.6 EKX40175.1 - 0.19 11.6 4.4 0.34 10.8 4.4 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_14 PF17978.1 EKX40175.1 - 0.25 11.8 0.7 0.5 10.8 0.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_4 PF14570.6 EKX40175.1 - 0.28 11.0 5.3 0.55 10.1 5.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 EKX40175.1 - 2.9 8.0 5.7 6.2 6.9 5.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Mad3_BUB1_I PF08311.12 EKX40177.1 - 0.046 13.7 0.9 0.14 12.1 0.3 2.0 1 1 1 2 2 2 0 Mad3/BUB1 homology region 1 HEAT PF02985.22 EKX40178.1 - 0.014 15.6 0.4 0.58 10.6 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.6 EKX40178.1 - 0.037 14.4 0.2 0.31 11.5 0.0 2.6 2 0 0 2 2 2 0 HEAT repeats DHC_N1 PF08385.12 EKX40179.1 - 3e-144 481.7 18.8 3e-144 481.7 18.8 3.3 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 Dynein_C PF18199.1 EKX40179.1 - 3e-50 171.2 0.0 1.4e-49 169.0 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain DHC_N2 PF08393.13 EKX40179.1 - 7.2e-49 167.0 19.0 7.2e-49 167.0 19.0 4.2 5 0 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 MT PF12777.7 EKX40179.1 - 3.8e-46 157.7 10.1 1e-45 156.3 10.1 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 EKX40179.1 - 1.4e-37 128.9 0.1 1.9e-33 115.5 0.0 3.2 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_8 PF12780.7 EKX40179.1 - 1.8e-33 116.0 0.0 2.7e-32 112.1 0.0 3.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_lid_1 PF17857.1 EKX40179.1 - 1.1e-19 70.5 0.2 6.2e-19 68.1 0.2 2.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_9 PF12781.7 EKX40179.1 - 6.7e-17 61.4 2.5 3.1e-14 52.6 0.6 3.6 2 1 0 2 2 2 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 EKX40179.1 - 1.3e-16 60.9 0.0 4.8e-16 59.0 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_6 PF12774.7 EKX40179.1 - 2.6e-15 56.2 1.5 1.4e-13 50.5 0.1 3.6 3 1 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region Dynein_AAA_lid PF17852.1 EKX40179.1 - 3.3e-11 43.4 0.8 2e-10 40.8 0.8 2.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EKX40179.1 - 3.5e-09 36.8 0.0 3.6e-05 23.8 0.0 3.4 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EKX40179.1 - 2.9e-06 27.7 0.0 0.018 15.4 0.0 4.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EKX40179.1 - 0.00017 21.9 0.0 0.46 10.8 0.0 3.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EKX40179.1 - 0.00032 21.1 0.0 0.048 14.0 0.0 3.1 2 0 0 2 2 2 1 RNA helicase ATPase_2 PF01637.18 EKX40179.1 - 0.00051 20.0 0.0 1.3 8.9 0.0 3.3 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 EKX40179.1 - 0.00057 20.0 0.2 0.93 9.6 0.1 3.5 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA PF00004.29 EKX40179.1 - 0.00084 19.8 0.0 0.035 14.5 0.0 3.7 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EKX40179.1 - 0.00097 18.9 0.0 0.69 9.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EKX40179.1 - 0.0021 18.4 0.0 3.9 7.8 0.0 3.4 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.6 EKX40179.1 - 0.02 14.6 0.0 7.1 6.5 0.0 3.1 3 0 0 3 3 3 0 P-loop containing region of AAA domain Rnk_N PF14760.6 EKX40179.1 - 0.045 14.2 0.8 0.14 12.6 0.8 2.0 1 0 0 1 1 1 0 Rnk N-terminus RsgA_GTPase PF03193.16 EKX40179.1 - 0.049 13.5 0.0 6.4 6.6 0.0 3.6 4 0 0 4 4 3 0 RsgA GTPase Viral_helicase1 PF01443.18 EKX40179.1 - 0.058 13.1 0.0 0.26 11.0 0.0 2.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Dynein_heavy PF03028.15 EKX40179.1 - 0.092 12.8 0.0 0.32 11.1 0.0 2.0 1 0 0 1 1 1 0 Dynein heavy chain region D6 P-loop domain ABC_tran PF00005.27 EKX40179.1 - 1 9.9 4.3 14 6.2 0.0 4.6 5 0 0 5 5 4 0 ABC transporter Cas9-BH PF16593.5 EKX40179.1 - 3.3 7.5 6.7 0.45 10.3 1.3 2.4 2 0 0 2 2 2 0 Bridge helix of CRISPR-associated endonuclease Cas9 SWIRM PF04433.17 EKX40180.1 - 6.1e-21 74.6 0.0 6.7e-21 74.4 0.0 1.0 1 0 0 1 1 1 1 SWIRM domain NAD_binding_10 PF13460.6 EKX40182.1 - 0.017 15.0 0.0 0.2 11.6 0.0 2.4 2 1 0 2 2 2 0 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 EKX40182.1 - 0.026 13.8 0.1 0.069 12.5 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ion_trans PF00520.31 EKX40183.1 - 8.5e-141 467.3 77.7 1.9e-39 135.3 10.5 5.1 4 1 0 4 4 4 4 Ion transport protein PDZ_6 PF17820.1 EKX40183.1 - 0.015 15.1 0.1 0.034 14.0 0.1 1.7 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 EKX40183.1 - 0.027 14.8 0.0 0.067 13.6 0.0 1.6 1 0 0 1 1 1 0 PDZ domain ICMT PF04140.14 EKX40183.1 - 0.073 13.5 0.3 0.68 10.4 0.0 2.7 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Lustrin_cystein PF14625.6 EKX40183.1 - 0.17 12.3 1.2 0.39 11.1 1.2 1.6 1 0 0 1 1 1 0 Lustrin, cysteine-rich repeated domain DUF1635 PF07795.11 EKX40183.1 - 5.8 6.7 15.7 5.1 6.9 4.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Zn-C2H2_12 PF18112.1 EKX40185.1 - 0.012 16.0 3.7 0.073 13.5 0.2 2.7 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain EF-hand_1 PF00036.32 EKX40186.1 - 8.4e-09 34.4 1.4 8e-08 31.3 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EKX40186.1 - 1.9e-08 34.7 0.0 2.4e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX40186.1 - 3.1e-08 32.9 0.2 7.6e-07 28.6 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 EKX40186.1 - 6.3e-08 31.8 0.1 1.1e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 EKX40186.1 - 0.00045 20.0 1.2 0.0013 18.6 0.1 2.1 2 1 1 3 3 3 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX40186.1 - 0.009 16.3 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region RST PF12174.8 EKX40186.1 - 0.032 14.2 0.0 0.093 12.7 0.0 1.7 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain Dockerin_1 PF00404.18 EKX40186.1 - 0.042 14.1 0.1 0.081 13.1 0.0 1.6 2 0 0 2 2 2 0 Dockerin type I domain S_100 PF01023.19 EKX40186.1 - 0.054 13.2 0.2 0.13 12.0 0.1 1.6 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain DnaJ PF00226.31 EKX40187.1 - 5.9e-24 84.0 4.0 1.3e-23 82.8 4.0 1.5 1 1 0 1 1 1 1 DnaJ domain DUF1986 PF09342.11 EKX40187.1 - 0.1 13.0 0.1 0.14 12.6 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1986) Spindle_Spc25 PF08234.12 EKX40188.1 - 1.5e-19 70.0 0.1 1.5e-19 70.0 0.1 2.7 3 0 0 3 3 3 1 Chromosome segregation protein Spc25 KASH_CCD PF14662.6 EKX40188.1 - 2.5e-05 24.2 17.3 3.4e-05 23.7 17.3 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH TPR_MLP1_2 PF07926.12 EKX40188.1 - 0.0036 17.4 17.5 0.0049 16.9 15.9 1.6 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein Cep57_MT_bd PF06657.13 EKX40188.1 - 0.01 16.2 15.7 0.025 15.0 5.7 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF3584 PF12128.8 EKX40188.1 - 0.032 11.7 13.8 0.034 11.7 12.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) FapA PF03961.13 EKX40188.1 - 0.038 12.6 8.8 0.047 12.3 8.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4200 PF13863.6 EKX40188.1 - 0.068 13.6 24.1 0.36 11.3 12.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) WEMBL PF05701.11 EKX40188.1 - 0.084 11.6 13.0 0.12 11.1 13.0 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light TnpV PF14198.6 EKX40188.1 - 0.087 12.8 6.3 0.091 12.8 5.2 1.6 1 1 0 1 1 1 0 Transposon-encoded protein TnpV Lectin_N PF03954.14 EKX40188.1 - 0.092 12.5 11.4 0.75 9.5 0.8 2.2 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain AAA_31 PF13614.6 EKX40188.1 - 0.093 12.6 2.3 8.5 6.3 0.0 2.2 1 1 1 2 2 2 0 AAA domain DUF3450 PF11932.8 EKX40188.1 - 0.1 11.9 8.6 0.15 11.3 8.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SAM_KSR1 PF13543.6 EKX40188.1 - 0.11 12.7 7.2 0.22 11.6 6.5 1.9 1 1 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 Filament PF00038.21 EKX40188.1 - 0.11 12.1 16.9 0.039 13.5 12.4 1.9 1 1 1 2 2 2 0 Intermediate filament protein Cas_Csy3 PF09615.10 EKX40188.1 - 0.15 11.3 3.0 0.23 10.7 3.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy3) KLRAQ PF10205.9 EKX40188.1 - 0.2 11.9 13.7 0.31 11.3 12.1 2.0 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Exonuc_VII_L PF02601.15 EKX40188.1 - 0.2 11.2 8.1 0.24 10.9 8.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Baculo_PEP_C PF04513.12 EKX40188.1 - 0.21 11.6 6.0 0.27 11.2 4.1 2.0 2 1 1 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TTKRSYEDQ PF10212.9 EKX40188.1 - 0.24 10.3 10.9 0.32 9.9 10.9 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein V_ATPase_I PF01496.19 EKX40188.1 - 0.28 9.1 6.3 0.27 9.1 6.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin PF02996.17 EKX40188.1 - 0.3 11.0 9.8 2 8.4 0.8 2.6 1 1 1 2 2 2 0 Prefoldin subunit HAUS6_N PF14661.6 EKX40188.1 - 0.49 9.9 10.6 0.78 9.3 10.6 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Spc7 PF08317.11 EKX40188.1 - 0.56 9.0 18.7 1 8.1 18.7 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Fzo_mitofusin PF04799.13 EKX40188.1 - 0.56 9.7 8.9 0.21 11.1 4.5 2.3 1 1 1 2 2 2 0 fzo-like conserved region Seryl_tRNA_N PF02403.22 EKX40188.1 - 0.58 10.4 14.0 0.29 11.4 10.8 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Prominin PF05478.11 EKX40188.1 - 0.6 8.0 7.4 0.74 7.7 7.4 1.1 1 0 0 1 1 1 0 Prominin Golgin_A5 PF09787.9 EKX40188.1 - 0.81 9.1 16.5 1.1 8.7 16.5 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 CENP-H PF05837.12 EKX40188.1 - 1 9.8 17.5 0.89 10.0 8.2 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) ZapB PF06005.12 EKX40188.1 - 1.1 9.8 19.1 0.066 13.7 8.6 2.6 1 1 1 2 2 2 0 Cell division protein ZapB JIP_LZII PF16471.5 EKX40188.1 - 1.4 9.1 14.8 0.46 10.7 5.9 2.7 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II FliD_N PF02465.18 EKX40188.1 - 1.5 9.6 8.6 26 5.6 8.6 2.4 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Prefoldin_2 PF01920.20 EKX40188.1 - 1.5 8.8 18.1 1.2 9.2 1.2 2.8 2 1 1 3 3 3 0 Prefoldin subunit Phage_GPO PF05929.11 EKX40188.1 - 1.7 8.2 8.6 3.1 7.3 8.6 1.5 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Vfa1 PF08432.10 EKX40188.1 - 1.9 8.8 10.7 2.6 8.4 10.7 1.3 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 APG6_N PF17675.1 EKX40188.1 - 2.1 8.9 20.3 7.3 7.1 20.3 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF16 PF01519.16 EKX40188.1 - 2.3 8.7 11.1 5.4 7.6 11.0 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 UPF0242 PF06785.11 EKX40188.1 - 3.3 7.8 16.8 4.9 7.2 16.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF948 PF06103.11 EKX40188.1 - 3.9 7.8 6.3 15 5.9 1.6 2.6 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) Atg14 PF10186.9 EKX40188.1 - 4.2 6.4 16.1 9.9 5.1 16.1 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SlyX PF04102.12 EKX40188.1 - 5.3 7.7 9.4 2.6 8.8 1.3 3.1 2 1 1 3 3 2 0 SlyX AAA_11 PF13086.6 EKX40188.1 - 5.3 6.8 10.7 6.9 6.4 10.7 1.2 1 0 0 1 1 1 0 AAA domain DUF745 PF05335.13 EKX40188.1 - 6.6 6.4 9.9 2.4 7.8 7.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Syntaxin-6_N PF09177.11 EKX40188.1 - 6.7 7.3 11.3 3.1 8.4 3.3 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TEX13 PF15186.6 EKX40188.1 - 6.9 6.3 10.9 0.22 11.2 2.7 2.3 2 1 1 3 3 2 0 Testis-expressed sequence 13 protein family DUF4094 PF13334.6 EKX40188.1 - 7.5 7.0 8.9 9.8 6.7 8.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) OmpH PF03938.14 EKX40188.1 - 7.8 6.8 18.6 2 8.7 2.4 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF1664 PF07889.12 EKX40188.1 - 8.7 6.4 11.5 11 6.1 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2723 PF11028.8 EKX40189.1 - 2.3e-28 99.2 1.8 2.3e-28 99.2 1.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2723) HUN PF08729.10 EKX40190.1 - 0.36 10.9 7.3 0.3 11.1 5.1 2.1 2 0 0 2 2 2 0 HPC2 and ubinuclein domain 14-3-3 PF00244.20 EKX40191.1 - 2.2e-96 321.6 3.0 3e-96 321.2 3.0 1.2 1 0 0 1 1 1 1 14-3-3 protein IFT20 PF14931.6 EKX40191.1 - 0.075 13.2 0.8 0.17 12.1 0.8 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 AnfO_nitrog PF09582.10 EKX40191.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) PDZ PF00595.24 EKX40192.1 - 0.02 15.2 0.0 0.047 14.1 0.0 1.6 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 EKX40192.1 - 0.021 14.7 0.0 0.047 13.5 0.0 1.6 1 0 0 1 1 1 0 PDZ domain IgGFc_binding PF17517.2 EKX40192.1 - 0.1 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 IgGFc binding protein DZR PF12773.7 EKX40193.1 - 0.42 10.7 5.3 11 6.1 1.0 2.9 3 0 0 3 3 3 0 Double zinc ribbon STAC2_u1 PF16664.5 EKX40193.1 - 1 9.8 4.5 0.77 10.2 2.3 1.9 1 1 1 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 AI-2E_transport PF01594.16 EKX40194.1 - 6.1e-22 78.2 32.6 4.4e-21 75.4 32.6 2.2 1 1 0 1 1 1 1 AI-2E family transporter Vma12 PF11712.8 EKX40194.1 - 2 8.5 6.1 2 8.5 1.8 2.6 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Mito_carr PF00153.27 EKX40195.1 - 1.8e-38 130.4 4.4 6.5e-18 64.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 EKX40195.1 - 0.0007 19.8 0.1 0.6 10.4 0.0 3.2 3 0 0 3 3 3 1 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase VIT1 PF01988.19 EKX40195.1 - 0.5 10.2 4.7 0.35 10.7 1.6 2.0 1 1 1 2 2 2 0 VIT family Mito_carr PF00153.27 EKX40197.1 - 2.6e-61 203.6 1.8 6.5e-21 74.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EKX40197.1 - 0.0014 17.8 0.6 0.72 9.0 0.0 2.8 3 0 0 3 3 3 2 Gammaproteobacterial serine protease ARID PF01388.21 EKX40198.1 - 1e-18 67.8 1.0 3.8e-11 43.5 0.5 2.5 2 0 0 2 2 2 2 ARID/BRIGHT DNA binding domain PolyA_pol_RNAbd PF12627.7 EKX40198.1 - 0.17 11.7 0.6 19 5.1 0.0 2.8 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A DUF1126 PF06565.12 EKX40199.1 - 2.4e-75 249.1 0.5 2.2e-27 95.0 0.1 3.1 3 0 0 3 3 3 3 DUF1126 PH-like domain IMCp PF12314.8 EKX40200.1 - 0.31 11.3 46.5 0.093 13.0 15.0 3.9 1 1 2 3 3 3 0 Inner membrane complex protein WD40 PF00400.32 EKX40201.1 - 0.086 13.7 15.8 16 6.6 0.0 6.5 6 0 0 6 6 6 0 WD domain, G-beta repeat Ion_trans_2 PF07885.16 EKX40202.1 - 1.1e-07 31.7 2.4 2.5e-07 30.5 2.4 1.6 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EKX40202.1 - 7.9e-05 22.0 13.1 0.045 13.0 13.1 2.2 1 1 0 1 1 1 1 Ion transport protein Arm PF00514.23 EKX40203.1 - 1e-26 92.0 9.5 3.2e-05 23.8 0.1 5.7 6 0 0 6 6 6 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EKX40203.1 - 8.2e-08 32.5 2.9 0.016 15.6 0.0 3.8 2 2 1 3 3 3 3 HEAT repeats HEAT_EZ PF13513.6 EKX40203.1 - 7.6e-07 29.5 1.9 0.05 14.1 0.0 3.9 4 0 0 4 4 4 2 HEAT-like repeat HEAT PF02985.22 EKX40203.1 - 3.8e-05 23.6 3.6 0.63 10.4 0.0 4.5 5 0 0 5 5 5 2 HEAT repeat Arm_2 PF04826.13 EKX40203.1 - 0.00014 21.4 5.2 0.48 9.8 0.1 3.8 2 2 0 3 3 3 2 Armadillo-like V-ATPase_H_C PF11698.8 EKX40203.1 - 0.00017 21.7 1.7 0.51 10.5 0.0 3.6 2 2 2 4 4 4 2 V-ATPase subunit H Cnd3 PF12719.7 EKX40203.1 - 0.00023 20.5 6.0 0.00041 19.6 0.4 2.4 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain SAPS PF04499.15 EKX40203.1 - 0.085 11.6 11.3 2 7.1 0.0 3.8 2 1 2 4 4 4 0 SIT4 phosphatase-associated protein DNA_pol_B_palm PF14792.6 EKX40203.1 - 0.097 12.9 0.8 3.2 8.0 0.0 2.8 2 1 1 3 3 3 0 DNA polymerase beta palm Symplekin_C PF12295.8 EKX40203.1 - 0.53 10.4 5.6 2.5 8.1 0.3 3.3 2 1 1 3 3 3 0 Symplekin tight junction protein C terminal PAN_4 PF14295.6 EKX40205.1 - 2.6e-06 27.2 2.1 5.4e-06 26.2 2.1 1.5 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 EKX40205.1 - 1.1e-05 25.3 0.1 2.5e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 PAN domain Myb_DNA-binding PF00249.31 EKX40206.1 - 9.5e-28 96.1 5.5 5e-16 58.6 0.1 2.8 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX40206.1 - 7e-20 71.0 2.7 1.6e-11 44.3 0.5 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF2448 PF10476.9 EKX40206.1 - 5.2e-06 26.5 0.3 2.4e-05 24.3 0.1 1.8 1 1 1 2 2 2 1 Protein of unknown function C-terminus (DUF2448) Myb_DNA-bind_4 PF13837.6 EKX40206.1 - 0.00077 19.8 2.2 0.083 13.3 0.2 2.8 2 2 1 3 3 3 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 EKX40206.1 - 0.0014 18.9 0.4 0.11 12.9 0.1 2.1 1 1 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_2 PF08914.11 EKX40206.1 - 0.0074 16.4 0.5 1.8 8.8 0.1 2.9 1 1 2 3 3 3 1 Rap1 Myb domain Rap1_C PF11626.8 EKX40206.1 - 0.05 13.7 1.2 6.5 6.9 0.2 2.2 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 EKX40206.1 - 0.063 13.2 0.0 3.9 7.4 0.0 3.0 1 1 1 2 2 2 0 Myb DNA-binding like Myb_DNA-bind_5 PF13873.6 EKX40206.1 - 0.13 12.4 5.1 10 6.3 0.4 3.8 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain Ion_trans PF00520.31 EKX40207.1 - 8e-190 627.8 86.3 1.1e-52 178.7 14.7 5.3 5 0 0 5 5 5 5 Ion transport protein GPHH PF16905.5 EKX40207.1 - 1.5e-11 43.9 0.0 4e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 EKX40207.1 - 1.2e-05 24.2 76.2 0.00011 21.0 2.6 9.3 7 4 1 8 8 8 7 Polycystin cation channel RRM_1 PF00076.22 EKX40208.1 - 1.5e-17 63.1 0.2 1.4e-10 40.9 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.12 EKX40208.1 - 0.12 12.6 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 RNA recognition motif 2 Thioredoxin PF00085.20 EKX40209.1 - 1.3e-16 60.4 0.0 2.1e-12 47.0 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin DnaJ PF00226.31 EKX40209.1 - 2.7e-12 46.6 0.0 6.2e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain AhpC-TSA PF00578.21 EKX40209.1 - 0.065 13.2 0.4 3.6 7.5 0.1 2.6 3 0 0 3 3 3 0 AhpC/TSA family Thioredoxin_8 PF13905.6 EKX40209.1 - 0.069 13.5 0.1 0.27 11.6 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like PMI_typeI PF01238.21 EKX40209.1 - 0.14 11.3 0.5 0.29 10.3 0.1 1.6 1 1 1 2 2 2 0 Phosphomannose isomerase type I Ldh_1_C PF02866.18 EKX40210.1 - 7.2e-45 152.9 0.0 1.1e-44 152.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EKX40210.1 - 1.1e-43 148.7 0.0 1.6e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EKX40210.1 - 7e-05 22.0 0.0 0.0003 19.9 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EKX40210.1 - 0.028 14.3 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding PAN_2 PF08276.11 EKX40210.1 - 0.54 10.4 4.4 0.55 10.4 0.4 2.5 2 0 0 2 2 2 0 PAN-like domain PAP_fibrillin PF04755.12 EKX40211.1 - 8.4e-09 35.6 0.1 1.3e-08 35.0 0.1 1.4 1 0 0 1 1 1 1 PAP_fibrillin BicD PF09730.9 EKX40211.1 - 0.025 13.0 0.8 0.037 12.5 0.8 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D MTHFR PF02219.17 EKX40212.1 - 4.3e-117 390.5 0.0 6.3e-117 390.0 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase I-set PF07679.16 EKX40212.1 - 0.099 12.7 0.0 3.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin I-set domain PAXNEB PF05625.11 EKX40214.1 - 3.6e-46 158.0 0.0 5.9e-46 157.3 0.0 1.3 1 0 0 1 1 1 1 PAXNEB protein DUF3402 PF11882.8 EKX40215.1 - 1e-24 87.5 0.2 2.8e-18 66.3 0.0 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF3402) UQ_con PF00179.26 EKX40216.1 - 4.5e-44 149.5 0.0 5.8e-44 149.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.31 EKX40216.1 - 1e-08 34.9 0.0 2.3e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.6 EKX40216.1 - 6.8e-05 22.6 0.0 0.00032 20.4 0.0 1.9 1 1 1 2 2 2 1 Prokaryotic E2 family B CUE PF02845.16 EKX40216.1 - 0.0045 16.7 0.0 0.0085 15.8 0.0 1.5 1 0 0 1 1 1 1 CUE domain HOIP-UBA PF16678.5 EKX40216.1 - 0.012 15.6 0.4 0.024 14.6 0.2 1.6 1 1 0 1 1 1 0 HOIP UBA domain pair RWD PF05773.22 EKX40216.1 - 0.019 15.2 0.0 0.029 14.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain AAA_18 PF13238.6 EKX40217.1 - 2.3e-27 96.1 0.0 3.1e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EKX40217.1 - 4.6e-08 33.6 0.8 3.5e-07 30.7 0.1 2.2 2 1 1 3 3 3 1 AAA domain AAA PF00004.29 EKX40217.1 - 1.2e-05 25.7 0.1 3.5e-05 24.2 0.1 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EKX40217.1 - 1.8e-05 24.9 0.3 0.00042 20.5 0.2 2.2 1 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EKX40217.1 - 4.5e-05 23.7 0.2 0.0001 22.6 0.1 1.8 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EKX40217.1 - 0.00021 21.2 0.6 0.00021 21.2 0.6 1.7 2 0 0 2 2 2 1 NTPase ADK PF00406.22 EKX40217.1 - 0.00027 21.0 0.2 0.0032 17.6 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase Mg_chelatase PF01078.21 EKX40217.1 - 0.00071 19.0 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EKX40217.1 - 0.00086 19.6 0.0 0.0014 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EKX40217.1 - 0.001 19.5 0.1 0.0015 18.9 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 EKX40217.1 - 0.0012 19.2 0.1 0.0019 18.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EKX40217.1 - 0.0027 17.7 0.0 0.0048 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.17 EKX40217.1 - 0.0044 16.7 0.2 1.2 8.7 0.1 2.1 2 0 0 2 2 2 1 Thymidylate kinase KTI12 PF08433.10 EKX40217.1 - 0.0044 16.5 0.0 0.0069 15.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_24 PF13479.6 EKX40217.1 - 0.0052 16.5 0.1 0.014 15.1 0.1 1.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EKX40217.1 - 0.011 15.1 0.0 0.028 13.7 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin ATPase PF06745.13 EKX40217.1 - 0.013 14.9 0.6 0.052 12.9 0.1 1.9 2 0 0 2 2 2 0 KaiC AAA_30 PF13604.6 EKX40217.1 - 0.014 15.2 0.3 0.02 14.6 0.3 1.2 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EKX40217.1 - 0.014 15.2 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EKX40217.1 - 0.018 15.4 0.1 0.042 14.2 0.0 1.7 2 0 0 2 2 1 0 RNA helicase SRP54 PF00448.22 EKX40217.1 - 0.018 14.7 0.2 0.032 13.9 0.2 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.18 EKX40217.1 - 0.022 14.1 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.12 EKX40217.1 - 0.025 14.5 0.1 0.046 13.6 0.1 1.4 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 EKX40217.1 - 0.034 13.2 0.1 0.055 12.5 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein CbiA PF01656.23 EKX40217.1 - 0.037 14.1 0.0 0.037 14.1 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain dNK PF01712.19 EKX40217.1 - 0.058 13.2 0.9 1.7 8.5 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase DUF2075 PF09848.9 EKX40217.1 - 0.06 12.6 0.1 0.088 12.0 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.17 EKX40217.1 - 0.067 12.3 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 MeaB PF03308.16 EKX40217.1 - 0.074 12.0 0.2 0.14 11.1 0.2 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TrwB_AAD_bind PF10412.9 EKX40217.1 - 0.082 11.8 0.1 0.11 11.3 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_11 PF13086.6 EKX40217.1 - 0.085 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EKX40217.1 - 0.085 12.6 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 EKX40217.1 - 0.11 12.3 0.1 0.66 9.8 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain PRK PF00485.18 EKX40217.1 - 0.11 12.2 0.0 0.74 9.5 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_7 PF12775.7 EKX40217.1 - 0.12 11.8 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 EKX40217.1 - 0.15 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_3 PF07726.11 EKX40217.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF853 PF05872.12 EKX40217.1 - 0.19 10.3 0.2 0.27 9.8 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Pkinase PF00069.25 EKX40218.1 - 8.4e-41 140.1 0.0 9.7e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX40218.1 - 6.2e-40 137.1 0.0 7e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX40218.1 - 0.00093 18.1 0.0 0.0012 17.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EKX40218.1 - 0.0015 18.0 0.1 0.002 17.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EKX40218.1 - 0.025 13.9 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 EKX40218.1 - 0.029 13.3 0.0 0.039 12.9 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EKX40218.1 - 0.033 14.1 0.0 0.045 13.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family SET PF00856.28 EKX40220.1 - 2.3e-16 60.7 1.1 1.2e-14 55.0 1.1 2.0 1 1 0 1 1 1 1 SET domain DUF4869 PF16163.5 EKX40220.1 - 0.14 11.8 0.1 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4869) TAP_C PF03943.13 EKX40221.1 - 0.072 12.7 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 TAP C-terminal domain Ldh_2 PF02615.14 EKX40222.1 - 8e-70 235.6 0.5 1e-69 235.3 0.5 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase DHHC PF01529.20 EKX40223.1 - 3.7e-17 62.7 5.3 3.7e-17 62.7 5.3 2.7 2 1 0 2 2 2 1 DHHC palmitoyltransferase Dynamitin PF04912.14 EKX40224.1 - 4.8e-32 111.7 7.5 1.7e-30 106.6 8.0 1.9 1 1 1 2 2 2 2 Dynamitin HWE_HK PF07536.14 EKX40224.1 - 0.032 14.9 4.2 0.35 11.6 0.6 3.5 3 1 1 4 4 4 0 HWE histidine kinase DUF4094 PF13334.6 EKX40224.1 - 0.048 14.1 0.3 0.048 14.1 0.3 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4094) CorA PF01544.18 EKX40224.1 - 0.12 11.7 2.6 0.1 11.9 0.4 1.8 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein CENP-Q PF13094.6 EKX40224.1 - 0.18 12.0 9.6 0.18 12.0 6.7 2.4 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Baculo_PEP_C PF04513.12 EKX40224.1 - 0.36 10.9 4.9 2.9 7.9 2.3 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SKA2 PF16740.5 EKX40224.1 - 0.74 9.6 6.2 0.75 9.6 0.6 3.0 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 Fib_alpha PF08702.10 EKX40224.1 - 1.7 8.8 5.5 4 7.6 0.4 3.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family TRPM_tetra PF16519.5 EKX40224.1 - 2.2 8.4 5.6 47 4.2 0.1 4.1 5 0 0 5 5 5 0 Tetramerisation domain of TRPM CK2S PF15011.6 EKX40224.1 - 3.4 7.5 8.3 0.27 11.1 2.2 2.2 3 0 0 3 3 3 0 Casein Kinase 2 substrate SH3_3 PF08239.11 EKX40225.1 - 0.011 16.0 0.0 1.1 9.7 0.0 2.5 2 0 0 2 2 2 0 Bacterial SH3 domain DUF4131 PF13567.6 EKX40225.1 - 0.018 14.7 0.9 0.018 14.7 0.9 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) BTB PF00651.31 EKX40226.1 - 8e-17 61.5 0.0 1.9e-16 60.2 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Adeno_terminal PF02459.15 EKX40228.1 - 0.035 12.5 1.3 0.05 12.0 1.3 1.3 1 0 0 1 1 1 0 Adenoviral DNA terminal protein DUF3891 PF13030.6 EKX40228.1 - 1.3 8.7 6.3 0.12 12.2 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3891) Aminotran_4 PF01063.19 EKX40229.1 - 2.8e-35 122.2 0.0 3.4e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Potassium_chann PF11404.8 EKX40230.1 - 0.16 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Potassium voltage-gated channel MORN PF02493.20 EKX40232.1 - 2.2e-77 250.5 84.5 1.2e-07 31.2 1.1 15.7 14 1 2 16 16 16 14 MORN repeat Tcp10_C PF07202.13 EKX40232.1 - 0.039 13.9 4.6 2.8 7.9 0.0 3.5 2 1 0 3 3 3 0 T-complex protein 10 C-terminus PATR PF12951.7 EKX40232.1 - 0.2 11.8 3.3 14 5.9 0.1 3.9 2 1 0 2 2 2 0 Passenger-associated-transport-repeat Rib PF08428.10 EKX40232.1 - 1.5 8.9 5.3 12 5.9 0.1 3.2 3 1 0 3 3 3 0 Rib/alpha-like repeat DUF3048_C PF17479.2 EKX40232.1 - 2.1 8.8 19.6 2.8 8.4 0.5 6.0 3 3 2 6 6 6 0 Protein of unknown function (DUF3048) C-terminal domain C2 PF00168.30 EKX40233.1 - 6.7e-20 71.3 0.0 1.8e-19 69.9 0.0 1.7 2 0 0 2 2 2 1 C2 domain EF-hand_1 PF00036.32 EKX40234.1 - 3.3e-08 32.5 1.9 7.3e-08 31.4 1.9 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EKX40234.1 - 8e-06 25.4 1.4 8e-06 25.4 1.4 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 EKX40234.1 - 5.1e-05 22.6 1.2 5.1e-05 22.6 1.2 1.8 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EKX40234.1 - 0.00049 20.5 2.0 0.00063 20.2 0.9 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 EKX40234.1 - 0.0017 18.2 1.0 0.0032 17.3 1.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_4 PF12763.7 EKX40234.1 - 0.084 12.8 0.6 0.17 11.8 0.6 1.5 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Ank_2 PF12796.7 EKX40235.1 - 3.7e-07 30.6 0.0 1.2e-06 29.0 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) SH3_9 PF14604.6 EKX40235.1 - 2e-06 27.5 0.0 4.4e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Ank_5 PF13857.6 EKX40235.1 - 3.4e-06 27.2 0.0 0.0091 16.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) SH3_2 PF07653.17 EKX40235.1 - 1.6e-05 24.5 0.0 3.8e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EKX40235.1 - 3.9e-05 23.2 0.1 7.7e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain Ank_3 PF13606.6 EKX40235.1 - 0.00012 22.2 0.0 0.21 12.3 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EKX40235.1 - 0.0012 19.2 0.0 2.3 8.8 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EKX40235.1 - 0.0017 18.9 0.0 0.14 12.8 0.0 3.3 1 1 2 3 3 3 1 Ankyrin repeats (many copies) HET PF06985.11 EKX40236.1 - 3.3e-07 30.8 0.2 1.3e-05 25.6 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) C2 PF00168.30 EKX40237.1 - 7.6e-07 29.4 0.0 1.3e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain HalOD2 PF18547.1 EKX40238.1 - 0.02 14.8 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Halobacterial output domain 2 Cytidylate_kin2 PF13189.6 EKX40238.1 - 0.055 13.6 0.4 1.9 8.6 0.0 2.8 1 1 1 2 2 2 0 Cytidylate kinase-like family BTG PF07742.12 EKX40238.1 - 0.069 13.0 0.1 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 BTG family RFC1 PF08519.12 EKX40238.1 - 0.19 11.9 2.6 1 9.5 0.0 2.7 3 0 0 3 3 3 0 Replication factor RFC1 C terminal domain TF_Zn_Ribbon PF08271.12 EKX40238.1 - 0.41 10.2 2.3 9.6 5.8 0.1 2.7 2 0 0 2 2 2 0 TFIIB zinc-binding zf-RRN7 PF11781.8 EKX40238.1 - 0.79 9.5 3.2 8.2 6.2 0.6 2.7 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 LSM PF01423.22 EKX40239.1 - 5.7e-21 74.0 0.2 6.2e-21 73.9 0.2 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EKX40239.1 - 1.2e-05 25.4 0.0 1.3e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Hfq PF17209.3 EKX40239.1 - 0.087 12.5 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Hfq protein Avl9 PF09794.9 EKX40240.1 - 3.4e-67 226.8 0.0 4.5e-67 226.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 EKX40240.1 - 1.3e-07 31.5 3.1 0.0024 17.5 0.0 2.6 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.12 EKX40240.1 - 0.0082 16.6 0.0 0.026 15.0 0.0 1.8 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Beta_helix PF13229.6 EKX40241.1 - 0.00028 20.7 0.0 0.0044 16.9 0.0 2.0 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 EKX40241.1 - 0.024 13.9 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Ion_trans_2 PF07885.16 EKX40242.1 - 2.8e-05 24.0 6.5 9.2e-05 22.3 6.4 1.9 1 1 0 1 1 1 1 Ion channel SK_channel PF03530.14 EKX40242.1 - 0.00012 22.0 1.8 0.00092 19.2 1.8 2.3 1 1 0 1 1 1 1 Calcium-activated SK potassium channel Aldo_ket_red PF00248.21 EKX40244.1 - 1.3e-42 146.0 0.0 4.5e-41 141.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Methyltransf_24 PF13578.6 EKX40245.1 - 1.4e-11 45.4 0.1 2.3e-11 44.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain WD40 PF00400.32 EKX40246.1 - 1.3e-05 25.8 9.4 0.14 13.1 0.0 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.6 EKX40246.1 - 0.035 14.6 0.4 10 6.7 0.1 4.3 5 0 0 5 5 5 0 PQQ-like domain WD40 PF00400.32 EKX40247.1 - 2.5e-05 24.9 9.5 0.0013 19.6 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat Ribosomal_S6e PF01092.19 EKX40248.1 - 2.7e-60 201.8 0.5 5.7e-60 200.8 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e NTPase_1 PF03266.15 EKX40249.1 - 2.5e-07 30.7 0.1 1.6e-05 24.9 0.1 2.1 1 1 0 1 1 1 1 NTPase DUF2478 PF10649.9 EKX40249.1 - 0.0026 17.4 0.0 0.054 13.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2478) SLIDE PF09111.10 EKX40249.1 - 0.043 13.8 0.3 0.077 13.0 0.3 1.4 1 0 0 1 1 1 0 SLIDE V-SNARE_C PF12352.8 EKX40250.1 - 6.2e-10 39.2 10.9 2e-06 28.0 3.1 2.2 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus NPV_P10 PF05531.12 EKX40250.1 - 0.0031 18.0 5.1 0.15 12.5 0.8 2.8 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein Paramyx_P_V_C PF03210.13 EKX40250.1 - 0.0058 16.4 1.3 0.46 10.3 0.1 2.7 1 1 1 2 2 2 1 Paramyxovirus P/V phosphoprotein C-terminal MCPsignal PF00015.21 EKX40250.1 - 0.0092 15.8 3.3 0.78 9.5 1.0 2.2 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Sec20 PF03908.13 EKX40250.1 - 0.08 12.9 6.2 1.2 9.1 1.1 2.5 2 0 0 2 2 2 0 Sec20 DUF3552 PF12072.8 EKX40250.1 - 0.33 10.4 16.7 0.076 12.4 3.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3552) DUF4618 PF15397.6 EKX40250.1 - 0.37 10.2 11.7 0.42 10.0 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Jnk-SapK_ap_N PF09744.9 EKX40250.1 - 0.39 10.9 15.5 0.09 13.0 2.9 2.3 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF148 PF02520.17 EKX40250.1 - 0.61 10.2 10.2 0.55 10.4 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF148 CHDCT2 PF08074.11 EKX40250.1 - 0.82 9.8 5.7 0.74 10.0 0.8 2.2 2 1 0 2 2 2 0 CHDCT2 (NUC038) domain DUF948 PF06103.11 EKX40250.1 - 2.1 8.6 7.9 10 6.5 2.3 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 EKX40250.1 - 2.2 8.3 12.5 2.7 8.0 4.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 EKX40250.1 - 2.3 8.4 11.5 6.2 7.0 3.3 2.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.8 EKX40250.1 - 2.5 7.3 19.8 4.7 6.4 3.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TBCC_N PF16752.5 EKX40250.1 - 4.4 7.8 13.7 2.1 8.8 4.2 2.7 2 1 1 3 3 3 0 Tubulin-specific chaperone C N-terminal domain TMPIT PF07851.13 EKX40250.1 - 5.5 6.1 12.5 3.3 6.9 1.0 2.1 1 1 1 2 2 2 0 TMPIT-like protein Acetyltransf_13 PF13880.6 EKX40251.1 - 9.2e-24 83.2 0.0 1.5e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 EKX40251.1 - 5.7e-15 54.8 0.0 1.9e-14 53.2 0.0 2.0 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.25 EKX40251.1 - 9.6e-05 22.6 0.0 0.00018 21.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EKX40251.1 - 0.0012 19.2 0.0 0.0029 18.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EKX40251.1 - 0.0036 17.2 0.1 0.013 15.4 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DIM PF08194.12 EKX40252.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 DIM protein Prp18 PF02840.15 EKX40253.1 - 6.1e-58 194.9 0.1 7.6e-58 194.6 0.1 1.1 1 0 0 1 1 1 1 Prp18 domain S6OS1 PF15676.5 EKX40253.1 - 0.084 11.4 0.6 0.13 10.7 0.4 1.3 1 1 0 1 1 1 0 Six6 opposite strand transcript 1 family Ank_2 PF12796.7 EKX40254.1 - 1e-21 77.3 0.0 3.1e-10 40.5 0.0 3.2 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX40254.1 - 1.9e-17 63.4 0.5 1.3e-05 25.7 0.1 4.0 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX40254.1 - 6.6e-16 56.8 1.2 8.2e-05 22.7 0.1 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EKX40254.1 - 4.9e-12 45.8 0.8 0.00051 20.3 0.0 4.6 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX40254.1 - 3.2e-11 43.2 1.8 0.0077 16.6 0.1 4.6 5 0 0 5 5 5 3 Ankyrin repeat Acetyltransf_CG PF14542.6 EKX40255.1 - 9.2e-19 67.4 0.0 9.9e-19 67.3 0.0 1.0 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Exo_endo_phos PF03372.23 EKX40256.1 - 3e-05 23.7 0.1 4.5e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4303 PF14136.6 EKX40256.1 - 0.049 13.4 0.4 3.1 7.5 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4303) PfkB PF00294.24 EKX40257.1 - 4.5e-19 68.9 0.0 4.9e-19 68.7 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase GEMIN8 PF15348.6 EKX40258.1 - 0.0031 17.9 0.1 0.0097 16.2 0.0 1.7 1 1 1 2 2 2 1 Gemini of Cajal bodies-associated protein 8 DUF2001 PF09393.10 EKX40258.1 - 0.0085 16.1 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Phage tail tube protein Ribosomal_L1 PF00687.21 EKX40259.1 - 3.6e-43 147.7 6.9 4.4e-43 147.4 6.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF3671 PF12420.8 EKX40259.1 - 0.86 9.7 8.6 0.41 10.7 5.1 2.2 2 1 0 2 2 2 0 Protein of unknown function DUF5344 PF17279.2 EKX40259.1 - 6.3 7.4 8.9 3.6 8.2 0.2 3.3 4 0 0 4 4 4 0 Family of unknown function (DUF5344) SHIPPO-rpt PF07004.12 EKX40261.1 - 0.023 15.6 2.8 6.2 7.9 0.7 3.0 2 0 0 2 2 2 0 Sperm-tail PG-rich repeat PI3K_1B_p101 PF10486.9 EKX40261.1 - 0.042 11.6 3.6 0.072 10.9 3.6 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SmAKAP PF15127.6 EKX40261.1 - 0.046 14.9 2.3 0.046 14.9 2.3 2.8 3 0 0 3 3 3 0 Small membrane A-kinase anchor protein SpoIIIAH PF12685.7 EKX40261.1 - 1.1 9.1 12.4 0.54 10.0 6.4 2.4 2 0 0 2 2 2 0 SpoIIIAH-like protein AAA_23 PF13476.6 EKX40261.1 - 1.2 9.6 13.9 2.2 8.8 11.2 2.3 2 0 0 2 2 2 0 AAA domain Nop14 PF04147.12 EKX40261.1 - 3.5 5.7 36.6 6.5 4.8 36.6 1.4 1 0 0 1 1 1 0 Nop14-like family PRC2_HTH_1 PF18118.1 EKX40261.1 - 3.7 8.4 21.1 0.56 11.1 0.5 3.1 4 0 0 4 4 4 0 Polycomb repressive complex 2 tri-helical domain Glyco_transf_4 PF13439.6 EKX40263.1 - 0.00055 20.0 0.0 0.089 12.8 0.0 2.3 1 1 1 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EKX40263.1 - 0.012 16.0 0.5 0.53 10.7 0.4 2.5 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain TPR_2 PF07719.17 EKX40263.1 - 0.022 14.9 0.1 0.11 12.7 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX40263.1 - 0.038 13.9 0.1 0.14 12.1 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat AA_kinase PF00696.28 EKX40263.1 - 0.1 12.1 0.0 0.32 10.5 0.0 1.8 2 0 0 2 2 2 0 Amino acid kinase family TPR_12 PF13424.6 EKX40263.1 - 0.15 12.4 0.1 0.5 10.7 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 EKX40263.1 - 0.16 11.9 0.0 0.44 10.4 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat HetR_C PF18460.1 EKX40263.1 - 0.43 10.5 1.6 47 4.0 0.0 3.5 3 0 0 3 3 3 0 Heterocyst differentiation regulator C-terminal Hood domain Methyltransf_11 PF08241.12 EKX40264.1 - 9.4e-12 45.4 0.0 1.9e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX40264.1 - 5.9e-11 42.9 0.0 1.2e-10 42.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EKX40264.1 - 1.9e-06 27.7 0.0 3.5e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_31 PF13847.6 EKX40264.1 - 2.1e-06 27.6 0.0 3.5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX40264.1 - 8.8e-06 25.7 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain fn2 PF00040.19 EKX40264.1 - 4.2e-05 23.7 6.5 7.5e-05 22.9 6.5 1.4 1 0 0 1 1 1 1 Fibronectin type II domain Ubie_methyltran PF01209.18 EKX40264.1 - 0.0054 16.1 0.0 0.0091 15.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EKX40264.1 - 0.027 13.8 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Fe_bilin_red PF05996.12 EKX40265.1 - 2.9e-73 246.3 0.0 3.7e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 Ferredoxin-dependent bilin reductase Methyltransf_16 PF10294.9 EKX40266.1 - 3.9e-24 85.3 0.0 1.4e-23 83.5 0.0 1.7 1 1 0 1 1 1 1 Lysine methyltransferase Pescadillo_N PF06732.11 EKX40267.1 - 6.8e-109 363.6 1.7 6.8e-109 363.6 1.7 1.8 3 0 0 3 3 3 1 Pescadillo N-terminus BRCT_2 PF16589.5 EKX40267.1 - 2e-08 34.5 0.0 5.5e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EKX40267.1 - 0.00063 20.1 0.0 0.0019 18.5 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain GAGA_bind PF06217.12 EKX40267.1 - 0.38 11.0 8.8 0.47 10.7 2.4 2.4 2 0 0 2 2 2 0 GAGA binding protein-like family UQ_con PF00179.26 EKX40268.1 - 4e-51 172.3 0.0 4.5e-51 172.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EKX40268.1 - 1.9e-05 24.4 0.0 2.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EKX40268.1 - 0.038 14.3 0.0 0.071 13.4 0.0 1.7 1 1 0 1 1 1 0 RWD domain CDO_I PF05995.12 EKX40269.1 - 5.3e-25 87.7 0.2 1.2e-24 86.6 0.2 1.5 1 1 0 1 1 1 1 Cysteine dioxygenase type I Cupin_2 PF07883.11 EKX40269.1 - 0.024 14.3 0.2 2.4 7.9 0.1 2.7 2 0 0 2 2 2 0 Cupin domain Glyco_transf_15 PF01793.16 EKX40271.1 - 3.4e-18 66.0 0.1 1.3e-17 64.1 0.1 1.9 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase EAF PF09816.9 EKX40272.1 - 9.9e-12 45.1 0.0 1.7e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Spore_GerQ PF09671.10 EKX40272.1 - 0.2 11.7 0.0 0.4 10.7 0.0 1.4 1 0 0 1 1 1 0 Spore coat protein (Spore_GerQ) Cwf_Cwc_15 PF04889.12 EKX40272.1 - 0.25 11.1 14.0 0.19 11.4 3.9 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 EKX40272.1 - 0.58 8.2 5.9 0.77 7.8 5.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF4598 PF15370.6 EKX40272.1 - 5.9 7.4 8.9 4 7.9 1.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) GAF_2 PF13185.6 EKX40273.1 - 3.5e-14 53.3 0.0 2.1e-06 28.1 0.0 3.5 3 0 0 3 3 3 2 GAF domain GAF PF01590.26 EKX40273.1 - 5.8e-13 49.6 0.0 2e-06 28.4 0.0 3.4 3 0 0 3 3 3 3 GAF domain GAF_3 PF13492.6 EKX40273.1 - 0.033 14.5 0.0 6.2 7.2 0.0 3.5 3 1 0 3 3 3 0 GAF domain SpoVT_C PF15714.5 EKX40273.1 - 0.066 13.3 0.0 10 6.2 0.0 2.7 2 0 0 2 2 2 0 Stage V sporulation protein T C-terminal, transcription factor Tropomyosin PF00261.20 EKX40273.1 - 0.3 10.4 7.5 0.23 10.8 6.1 1.5 2 0 0 2 2 2 0 Tropomyosin Thioredoxin_8 PF13905.6 EKX40274.1 - 1.5e-34 118.2 0.1 8.9e-19 67.6 0.0 3.6 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EKX40274.1 - 8.4e-12 45.5 0.1 1.8e-05 25.2 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.21 EKX40274.1 - 4e-06 26.8 0.0 0.04 13.8 0.0 3.1 2 2 0 2 2 2 2 AhpC/TSA family Thioredoxin PF00085.20 EKX40274.1 - 8.5e-06 25.7 0.4 0.71 9.9 0.0 4.0 2 2 1 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EKX40274.1 - 0.0012 18.8 0.0 0.083 12.8 0.0 3.0 3 1 0 3 3 3 1 Thioredoxin-like domain Redoxin PF08534.10 EKX40274.1 - 0.031 14.0 0.0 0.88 9.3 0.0 2.5 2 1 0 2 2 2 0 Redoxin Thioredoxin_7 PF13899.6 EKX40274.1 - 0.033 14.4 1.8 10 6.4 0.3 3.2 2 2 0 2 2 2 0 Thioredoxin-like Ribosomal_60s PF00428.19 EKX40275.1 - 0.5 11.0 8.7 1.3 9.7 8.7 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3417 PF11897.8 EKX40276.1 - 0.082 13.4 1.3 0.13 12.7 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) Ubiquitin_4 PF18036.1 EKX40276.1 - 0.18 11.9 1.5 1.8 8.7 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain DUF4795 PF16043.5 EKX40276.1 - 0.68 9.5 12.5 0.94 9.0 12.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) zf-RING_2 PF13639.6 EKX40277.1 - 1.1e-11 44.9 12.2 1.2e-11 44.7 8.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX40277.1 - 3.2e-11 42.9 9.6 3.2e-11 42.9 9.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX40277.1 - 1.7e-08 34.6 9.9 1.7e-08 34.6 9.9 2.6 2 1 1 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EKX40277.1 - 1.1e-06 28.4 9.2 1.1e-06 28.4 9.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EKX40277.1 - 4e-06 26.6 12.2 4e-06 26.6 12.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX40277.1 - 1.7e-05 24.7 6.1 4.2e-05 23.5 6.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 EKX40277.1 - 2.7e-05 23.8 6.7 4e-05 23.2 3.7 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 EKX40277.1 - 0.0059 16.5 11.6 0.0059 16.5 11.6 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EKX40277.1 - 0.039 14.0 10.2 0.19 11.8 10.3 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Fe-ADH PF00465.19 EKX40277.1 - 0.047 12.5 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase zf-C3H2C3 PF17122.5 EKX40277.1 - 0.2 11.7 7.1 0.66 10.1 7.1 1.9 1 0 0 1 1 1 0 Zinc-finger zf-Nse PF11789.8 EKX40277.1 - 0.41 10.5 6.7 0.39 10.6 4.8 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 EKX40277.1 - 0.72 9.5 19.1 0.11 12.1 14.8 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Stn1 PF10451.9 EKX40278.1 - 2.8e-05 23.2 0.1 4e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 EKX40278.1 - 3e-05 23.9 0.1 5.9e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 EKX40278.1 - 0.0038 17.4 0.0 0.0075 16.4 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain eIF-5_eIF-2B PF01873.17 EKX40278.1 - 0.012 15.4 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Domain found in IF2B/IF5 Clathrin PF00637.20 EKX40279.1 - 2e-21 76.4 0.4 9.2e-19 67.7 0.1 3.5 4 0 0 4 4 4 1 Region in Clathrin and VPS WD40 PF00400.32 EKX40279.1 - 0.00035 21.3 0.0 0.0013 19.5 0.0 2.1 1 0 0 1 1 1 1 WD domain, G-beta repeat TPR_20 PF14561.6 EKX40279.1 - 0.0054 17.0 0.1 0.033 14.5 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Vps39_1 PF10366.9 EKX40279.1 - 0.0084 16.4 2.1 0.18 12.1 0.2 3.0 2 1 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 TPR_7 PF13176.6 EKX40279.1 - 0.59 10.3 3.6 44 4.4 0.1 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat DHC_N1 PF08385.12 EKX40280.1 - 1.7e-137 459.4 2.8 1.7e-137 459.4 2.8 4.0 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 EKX40280.1 - 5.5e-71 239.8 9.4 5.5e-71 239.8 9.4 4.3 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.7 EKX40280.1 - 5.8e-38 130.2 0.0 3.3e-33 114.7 0.0 3.7 4 0 0 4 4 3 2 P-loop containing dynein motor region MT PF12777.7 EKX40280.1 - 1.5e-35 122.8 8.5 1.5e-35 122.8 8.5 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.7 EKX40280.1 - 2.5e-28 99.1 0.0 3.6e-27 95.3 0.0 2.6 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EKX40280.1 - 2.4e-21 75.9 0.1 1.8e-20 73.0 0.0 2.6 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_6 PF12774.7 EKX40280.1 - 5.6e-18 65.0 0.0 3.8e-17 62.3 0.0 2.4 2 1 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region Dynein_AAA_lid PF17852.1 EKX40280.1 - 3.3e-14 53.1 0.1 1.4e-13 51.1 0.1 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 EKX40280.1 - 7e-10 39.6 9.5 0.0053 17.2 0.0 6.7 6 1 1 7 7 4 3 AAA ATPase domain AAA_5 PF07728.14 EKX40280.1 - 9.8e-09 35.3 0.1 0.0046 16.9 0.0 4.3 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EKX40280.1 - 3.1e-07 30.9 0.0 0.1 13.1 0.0 4.6 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EKX40280.1 - 4.3e-06 27.3 0.0 3.9 8.0 0.0 4.9 3 0 0 3 3 3 2 ABC transporter AAA_22 PF13401.6 EKX40280.1 - 3.1e-05 24.3 4.7 0.37 11.1 0.1 5.7 5 1 0 5 5 4 1 AAA domain AAA_29 PF13555.6 EKX40280.1 - 4e-05 23.3 0.9 1.7 8.5 0.1 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_lid_1 PF17857.1 EKX40280.1 - 7.2e-05 22.9 0.0 0.00041 20.5 0.0 2.4 1 0 0 1 1 1 1 AAA+ lid domain Mg_chelatase PF01078.21 EKX40280.1 - 0.00026 20.4 0.8 3.6 6.9 0.0 3.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EKX40280.1 - 0.00046 19.4 0.0 1 8.4 0.0 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 EKX40280.1 - 0.0018 18.5 0.0 4.1 7.6 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 EKX40280.1 - 0.0019 18.8 0.0 6.8 7.3 0.0 3.6 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.6 EKX40280.1 - 0.0031 17.5 0.0 8.8 6.4 0.0 3.8 3 0 0 3 3 3 0 AAA domain RuvB_N PF05496.12 EKX40280.1 - 0.0043 16.8 0.0 0.35 10.6 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 EKX40280.1 - 0.013 15.5 0.1 17 5.4 0.0 3.7 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EKX40280.1 - 0.015 15.5 0.4 0.92 9.7 0.0 3.7 3 0 0 3 3 2 0 AAA domain NACHT PF05729.12 EKX40280.1 - 0.023 14.6 0.5 47 3.8 0.0 4.7 5 0 0 5 5 3 0 NACHT domain AAA_19 PF13245.6 EKX40280.1 - 0.039 14.3 1.1 10 6.5 0.0 4.0 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 EKX40280.1 - 0.077 13.4 0.0 13 6.2 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_25 PF13481.6 EKX40280.1 - 0.092 12.3 0.7 41 3.7 0.1 3.8 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 EKX40280.1 - 0.14 11.7 0.2 45 3.6 0.0 3.5 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NPV_P10 PF05531.12 EKX40280.1 - 7.6 7.1 6.5 16 6.0 0.1 5.1 6 0 0 6 6 3 0 Nucleopolyhedrovirus P10 protein Methyltransf_11 PF08241.12 EKX40281.1 - 7e-18 65.1 0.0 1.1e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX40281.1 - 1.1e-17 64.4 0.0 2.1e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX40281.1 - 4e-13 49.5 0.0 7e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX40281.1 - 2.9e-12 46.4 0.0 4.1e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EKX40281.1 - 2.4e-11 43.7 0.0 1.1e-10 41.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX40281.1 - 2.6e-10 40.9 0.0 7.3e-10 39.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 EKX40281.1 - 0.00034 20.4 0.0 0.00048 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) MTS PF05175.14 EKX40281.1 - 0.00099 18.7 0.0 0.0015 18.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain CheR PF01739.18 EKX40281.1 - 0.034 13.6 0.0 1.4 8.4 0.0 2.2 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain Pkinase PF00069.25 EKX40282.1 - 1.2e-63 215.0 0.0 2.3e-63 214.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX40282.1 - 3.8e-38 131.2 0.0 6e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX40282.1 - 2.5e-08 33.6 0.0 8.8e-08 31.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EKX40282.1 - 9.2e-05 21.4 1.5 0.00052 18.9 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EKX40282.1 - 0.019 14.9 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EKX40282.1 - 0.031 13.9 1.6 0.12 12.0 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EKX40282.1 - 0.047 13.0 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2920 PF11144.8 EKX40282.1 - 0.07 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Seadorna_VP7 PF07387.11 EKX40282.1 - 0.097 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4288 PF14119.6 EKX40282.1 - 0.19 12.1 0.6 0.47 10.9 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) SOBP PF15279.6 EKX40282.1 - 0.81 10.2 5.3 1.2 9.7 5.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein AAA PF00004.29 EKX40284.1 - 4.8e-42 143.5 0.2 1.4e-41 142.0 0.0 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EKX40284.1 - 8.7e-11 41.6 0.0 2.9e-10 39.9 0.0 1.9 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EKX40284.1 - 8.1e-09 35.2 0.6 1.9e-08 33.9 0.6 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EKX40284.1 - 2.4e-07 31.3 0.0 0.00044 20.7 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EKX40284.1 - 3.6e-06 27.0 0.2 0.00011 22.2 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EKX40284.1 - 9.4e-06 25.4 0.0 2.3e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EKX40284.1 - 3.1e-05 24.2 0.0 0.00017 21.8 0.0 2.2 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EKX40284.1 - 0.00027 21.2 0.9 0.075 13.3 0.0 2.9 2 1 1 3 3 3 1 AAA domain Prot_ATP_OB_N PF17758.1 EKX40284.1 - 0.0032 17.1 0.1 0.01 15.5 0.0 1.8 2 0 0 2 2 1 1 Proteasomal ATPase OB N-terminal domain DUF815 PF05673.13 EKX40284.1 - 0.0035 16.5 0.0 0.0069 15.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 EKX40284.1 - 0.0043 17.6 0.5 0.038 14.5 0.0 2.5 2 2 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EKX40284.1 - 0.0053 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EKX40284.1 - 0.0053 17.1 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 EKX40284.1 - 0.0058 15.9 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EKX40284.1 - 0.0081 15.6 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EKX40284.1 - 0.0085 15.8 0.0 0.028 14.1 0.0 1.9 2 1 0 2 2 1 1 Sigma-54 interaction domain AAA_24 PF13479.6 EKX40284.1 - 0.011 15.5 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EKX40284.1 - 0.016 14.7 0.0 0.05 13.1 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 EKX40284.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 EKX40284.1 - 0.018 14.9 1.3 0.87 9.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain ATPase PF06745.13 EKX40284.1 - 0.029 13.7 0.3 0.17 11.2 0.0 2.3 3 0 0 3 3 3 0 KaiC AAA_14 PF13173.6 EKX40284.1 - 0.031 14.3 0.0 0.073 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EKX40284.1 - 0.036 13.2 0.0 0.065 12.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 EKX40284.1 - 0.044 13.6 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EKX40284.1 - 0.053 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EKX40284.1 - 0.057 13.0 0.4 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EKX40284.1 - 0.057 13.6 0.0 0.15 12.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 EKX40284.1 - 0.06 13.3 0.0 0.19 11.6 0.0 1.9 1 1 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 EKX40284.1 - 0.062 13.5 0.2 0.21 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EKX40284.1 - 0.074 12.8 0.1 0.19 11.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain Laminin_II PF06009.12 EKX40284.1 - 0.11 12.5 0.6 0.76 9.8 0.7 2.2 2 0 0 2 2 2 0 Laminin Domain II ABC_tran PF00005.27 EKX40284.1 - 0.13 12.8 0.1 0.47 11.0 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_21 PF13304.6 EKX40284.1 - 0.15 11.9 0.1 16 5.2 0.0 2.5 3 0 0 3 3 2 0 AAA domain, putative AbiEii toxin, Type IV TA system FapA PF03961.13 EKX40284.1 - 0.17 10.5 0.4 0.24 9.9 0.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA_23 PF13476.6 EKX40284.1 - 0.47 10.9 4.8 20 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Myosin_head PF00063.21 EKX40285.1 - 1.1e-180 602.2 0.0 1.7e-109 366.9 0.0 2.8 2 1 0 2 2 2 2 Myosin head (motor domain) AAA_22 PF13401.6 EKX40285.1 - 0.00029 21.1 0.0 0.002 18.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EKX40285.1 - 0.0003 21.2 0.0 0.006 17.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EKX40285.1 - 0.014 16.0 0.0 0.047 14.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EKX40285.1 - 0.017 14.4 0.0 0.057 12.7 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin Hpr_kinase_C PF07475.12 EKX40285.1 - 0.027 14.0 0.0 7.6 6.0 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Sigma54_activat PF00158.26 EKX40285.1 - 0.051 13.3 0.0 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 EKX40285.1 - 0.06 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Septin PF00735.18 EKX40285.1 - 0.097 11.9 0.8 7.7 5.7 0.4 2.2 2 0 0 2 2 2 0 Septin FtsK_SpoIIIE PF01580.18 EKX40285.1 - 0.14 11.4 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Protamine_like PF06382.11 EKX40289.1 - 0.11 12.7 0.8 0.17 12.1 0.8 1.3 1 0 0 1 1 1 0 Protamine and protamine like HMG_box_2 PF09011.10 EKX40289.1 - 0.82 10.3 12.2 0.13 12.9 7.3 2.1 1 1 1 2 2 2 0 HMG-box domain HMG_box PF00505.19 EKX40289.1 - 6.1 7.3 11.4 0.97 9.9 5.3 2.4 2 1 0 2 2 2 0 HMG (high mobility group) box OST-HTH PF12872.7 EKX40290.1 - 0.0033 17.2 0.0 0.0078 16.0 0.0 1.6 1 0 0 1 1 1 1 OST-HTH/LOTUS domain Tim17 PF02466.19 EKX40290.1 - 0.0043 17.4 0.0 0.0074 16.6 0.0 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Myb_DNA-binding PF00249.31 EKX40292.1 - 2.3e-34 117.3 2.4 1.3e-16 60.5 0.1 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX40292.1 - 5.8e-25 87.3 0.2 3.1e-15 56.2 0.0 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EKX40292.1 - 7.1e-07 29.0 0.0 0.022 14.7 0.0 2.1 1 1 1 2 2 2 2 Myb DNA-binding like Rap1_C PF11626.8 EKX40292.1 - 0.0058 16.7 0.3 3 8.0 0.0 2.1 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 EKX40292.1 - 0.011 15.7 0.0 2.2 8.3 0.0 2.4 1 1 1 2 2 2 0 SLIDE Myb_DNA-bind_2 PF08914.11 EKX40292.1 - 0.019 15.1 1.3 5 7.4 0.2 2.9 1 1 1 2 2 2 0 Rap1 Myb domain SANT_DAMP1_like PF16282.5 EKX40292.1 - 0.025 14.8 0.3 4.3 7.6 0.1 2.3 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_5 PF13873.6 EKX40292.1 - 0.15 12.1 2.8 37 4.5 0.0 3.4 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EKX40292.1 - 0.18 12.2 1.6 25 5.3 0.0 3.1 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Methyltransf_11 PF08241.12 EKX40293.1 - 5.5e-07 30.2 0.0 1e-06 29.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX40293.1 - 6.8e-06 26.0 0.2 1.4e-05 25.0 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX40293.1 - 0.00024 21.7 0.0 0.00053 20.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain AAA_16 PF13191.6 EKX40295.1 - 6.4e-13 49.4 0.3 6.4e-13 49.4 0.3 3.2 2 1 0 2 2 1 1 AAA ATPase domain ORC4_C PF14629.6 EKX40295.1 - 1e-09 38.1 4.2 1e-09 38.1 4.2 3.0 3 0 0 3 3 3 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_22 PF13401.6 EKX40295.1 - 2e-07 31.4 0.1 1.4e-06 28.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EKX40295.1 - 6.2e-06 26.7 0.0 2.8e-05 24.6 0.0 2.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EKX40295.1 - 0.00035 20.5 0.0 0.00035 20.5 0.0 2.2 2 0 0 2 2 1 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EKX40295.1 - 0.00065 20.0 0.0 0.0031 17.9 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 EKX40295.1 - 0.005 17.0 0.0 0.005 17.0 0.0 3.1 2 1 1 3 3 1 1 AAA domain AAA_5 PF07728.14 EKX40295.1 - 0.018 15.0 0.1 0.053 13.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 EKX40295.1 - 0.098 12.4 0.1 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 EKX40295.1 - 0.15 12.6 0.0 0.15 12.6 0.0 3.1 2 1 0 2 2 1 0 AAA domain AAA_11 PF13086.6 EKX40295.1 - 0.65 9.7 0.0 0.65 9.7 0.0 4.3 4 0 0 4 4 4 0 AAA domain Mem_trans PF03547.18 EKX40295.1 - 1.2 7.5 18.5 0.62 8.4 3.8 3.5 3 0 0 3 3 3 0 Membrane transport protein Plasmodium_Vir PF05795.11 EKX40295.1 - 4.4 6.6 43.8 0.18 11.2 12.4 3.5 3 0 0 3 3 3 0 Plasmodium vivax Vir protein VHP PF02209.19 EKX40296.1 - 0.012 15.6 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Villin headpiece domain VWA PF00092.28 EKX40297.1 - 5.5e-14 52.8 0.3 2.4e-12 47.4 0.0 3.1 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA_2 PF13519.6 EKX40297.1 - 1e-08 35.8 0.1 4.6e-08 33.7 0.1 2.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EKX40297.1 - 6.6e-07 29.4 0.0 4.6e-06 26.7 0.0 2.5 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 EKX40297.1 - 1.1e-05 24.9 0.0 2.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein AAA PF00004.29 EKX40297.1 - 0.00025 21.5 0.0 0.29 11.5 0.0 3.5 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) vWA-TerF-like PF10138.9 EKX40297.1 - 0.00039 20.6 0.0 0.003 17.7 0.0 2.4 2 0 0 2 2 2 1 vWA found in TerF C terminus KAP_NTPase PF07693.14 EKX40297.1 - 0.094 11.9 1.0 15 4.7 0.0 3.2 3 0 0 3 3 3 0 KAP family P-loop domain AAA_7 PF12775.7 EKX40298.1 - 5e-06 26.2 0.2 0.086 12.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_5 PF07728.14 EKX40298.1 - 1.2e-05 25.4 0.1 6.8e-05 22.9 0.1 2.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EKX40298.1 - 0.00045 20.6 1.2 2.2 8.7 0.0 3.6 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EKX40298.1 - 0.002 17.6 0.3 0.28 10.5 0.0 3.3 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EKX40298.1 - 0.0067 16.5 0.0 0.02 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EKX40298.1 - 0.0068 16.8 0.2 0.061 13.7 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain T2SSE PF00437.20 EKX40298.1 - 0.029 13.4 0.5 0.14 11.2 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.6 EKX40298.1 - 0.037 14.3 0.2 2 8.7 0.0 3.4 4 0 0 4 4 4 0 AAA domain ResIII PF04851.15 EKX40298.1 - 0.15 12.0 0.1 0.57 10.2 0.0 1.8 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Pkinase PF00069.25 EKX40299.1 - 4.6e-69 232.7 0.0 5.1e-69 232.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX40299.1 - 1.3e-43 149.2 0.0 1.5e-43 148.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX40299.1 - 1.6e-08 34.2 0.0 1.1e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EKX40299.1 - 4.5e-06 25.7 0.0 6.6e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX40299.1 - 0.0017 18.4 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EKX40299.1 - 0.011 15.4 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EKX40299.1 - 0.016 14.5 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EKX40299.1 - 0.078 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EKX40299.1 - 0.084 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.9 EKX40299.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Macoilin PF09726.9 EKX40300.1 - 2.7 6.5 4.8 2.6 6.5 4.8 1.0 1 0 0 1 1 1 0 Macoilin family Atg8 PF02991.16 EKX40301.1 - 7.4e-49 164.3 0.0 8.9e-49 164.0 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EKX40301.1 - 1e-06 29.0 0.0 1.3e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Tantalus PF15386.6 EKX40301.1 - 0.08 13.0 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Drosophila Tantalus-like LRR_4 PF12799.7 EKX40302.1 - 2.1e-18 66.1 10.0 2.4e-07 31.0 0.8 4.0 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX40302.1 - 2.1e-17 62.6 9.5 3.3e-09 36.4 0.2 4.3 3 2 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 EKX40302.1 - 4.6e-11 41.9 4.7 0.00069 19.5 0.0 5.8 6 0 0 6 6 6 3 Leucine Rich repeat LRR_1 PF00560.33 EKX40302.1 - 1e-05 25.4 7.7 1.6 9.5 0.0 5.8 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_9 PF14580.6 EKX40302.1 - 0.0015 18.1 0.4 0.014 14.9 0.2 2.0 1 1 1 2 2 2 1 Leucine-rich repeat Zn_ribbon_17 PF17120.5 EKX40303.1 - 1e-10 41.1 20.2 1.1e-08 34.6 13.2 2.6 1 1 1 2 2 2 2 Zinc-ribbon, C4HC2 type WD40 PF00400.32 EKX40303.1 - 2e-10 41.1 27.5 0.0043 17.9 0.7 7.8 8 0 0 8 8 8 3 WD domain, G-beta repeat eIF2A PF08662.11 EKX40303.1 - 7.1e-06 26.0 0.0 0.0013 18.7 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 EKX40303.1 - 0.00012 22.3 3.9 0.53 10.6 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain zinc_ribbon_16 PF17034.5 EKX40303.1 - 0.0012 19.0 5.8 0.0012 19.0 5.8 2.8 1 1 1 2 2 2 1 Zinc-ribbon like family Benyvirus_14KDa PF07255.11 EKX40303.1 - 0.065 13.5 0.3 0.23 11.7 0.1 2.0 2 0 0 2 2 2 0 Benyvirus 14KDa protein zinc_ribbon_15 PF17032.5 EKX40303.1 - 6.3 7.6 11.4 13 6.6 8.0 2.9 2 1 1 3 3 3 0 zinc-ribbon family UPF0547 PF10571.9 EKX40303.1 - 9 6.5 8.5 0.46 10.6 1.7 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 A-2_8-polyST PF07388.11 EKX40304.1 - 0.013 14.1 0.0 0.016 13.8 0.0 1.1 1 0 0 1 1 1 0 Alpha-2,8-polysialyltransferase (POLYST) Thioesterase PF00975.20 EKX40305.1 - 0.23 11.6 0.1 0.36 10.9 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain Glyco_transf_90 PF05686.12 EKX40306.1 - 2.9e-13 49.5 0.1 4.9e-07 29.0 0.1 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 90 Collagen_bind_2 PF12904.7 EKX40306.1 - 0.07 13.1 0.0 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 Putative collagen-binding domain of a collagenase Uso1_p115_C PF04871.13 EKX40307.1 - 0.027 14.9 8.0 0.061 13.7 8.0 1.6 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region UPF0242 PF06785.11 EKX40307.1 - 0.069 13.3 0.4 0.12 12.5 0.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cnn_1N PF07989.11 EKX40307.1 - 0.1 12.8 3.2 0.17 12.1 2.7 1.7 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 CENP-H PF05837.12 EKX40307.1 - 6.2 7.3 7.9 17 5.9 7.9 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) RWP-RK PF02042.15 EKX40308.1 - 5.4e-14 51.9 0.1 9.1e-14 51.2 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain Kelch_4 PF13418.6 EKX40310.1 - 2.9e-32 110.4 35.2 2.3e-05 24.3 0.3 14.8 15 0 0 15 15 15 8 Galactose oxidase, central domain Kelch_5 PF13854.6 EKX40310.1 - 5.1e-29 99.7 43.1 0.00014 21.7 0.3 13.9 15 0 0 15 15 15 8 Kelch motif Kelch_3 PF13415.6 EKX40310.1 - 8.5e-27 92.9 21.7 7.8e-05 22.9 0.0 15.5 17 0 0 17 17 17 6 Galactose oxidase, central domain Filamin PF00630.19 EKX40310.1 - 8.3e-23 81.2 0.0 5.3e-11 43.3 0.0 3.8 3 0 0 3 3 3 2 Filamin/ABP280 repeat Kelch_1 PF01344.25 EKX40310.1 - 6.4e-10 38.5 20.8 0.14 11.8 0.0 9.5 10 0 0 10 10 10 4 Kelch motif Invasin_D3 PF09134.10 EKX40310.1 - 8.1e-10 38.9 3.2 0.00015 22.0 0.1 4.1 4 0 0 4 4 4 2 Invasin, domain 3 Kelch_6 PF13964.6 EKX40310.1 - 1.8e-09 37.6 26.6 0.0093 16.2 0.1 11.6 12 0 0 12 12 12 2 Kelch motif Big_1 PF02369.16 EKX40310.1 - 0.042 13.9 3.7 12 6.0 0.1 4.7 4 1 0 4 4 4 0 Bacterial Ig-like domain (group 1) DUF3902 PF13042.6 EKX40310.1 - 0.09 12.4 0.3 2.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3902) YtkA PF13115.6 EKX40310.1 - 0.13 12.9 0.0 41 4.9 0.0 3.4 3 0 0 3 3 3 0 YtkA-like Lectin_C PF00059.21 EKX40311.1 - 3.9e-15 56.5 1.5 3.9e-15 56.5 1.5 2.9 3 0 0 3 3 3 1 Lectin C-type domain Ephrin_rec_like PF07699.13 EKX40311.1 - 0.0004 20.1 4.7 0.0004 20.1 4.7 2.5 2 0 0 2 2 2 1 Putative ephrin-receptor like SQS_PSY PF00494.19 EKX40313.1 - 8.1e-69 232.0 0.7 9.2e-69 231.9 0.7 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase PDZ_6 PF17820.1 EKX40314.1 - 2e-09 37.1 0.0 3.4e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX40314.1 - 5.3e-07 29.9 0.0 8.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX40314.1 - 0.0033 17.7 0.0 0.0061 16.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Beta_helix PF13229.6 EKX40315.1 - 5.5e-50 169.3 32.3 1.8e-20 73.3 12.5 3.0 1 1 2 3 3 3 3 Right handed beta helix region NosD PF05048.13 EKX40315.1 - 9.1e-35 120.1 16.5 9.9e-15 54.5 4.4 3.1 1 1 2 3 3 3 3 Periplasmic copper-binding protein (NosD) Pkinase PF00069.25 EKX40316.1 - 6.4e-59 199.5 0.0 7.3e-59 199.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX40316.1 - 4.1e-36 124.6 0.0 5.3e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX40316.1 - 2.1e-11 43.7 0.0 3e-08 33.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 EKX40316.1 - 7.8e-05 22.1 0.1 0.00011 21.6 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX40316.1 - 0.00061 19.8 0.0 0.0094 15.9 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EKX40316.1 - 0.011 14.8 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 EKX40316.1 - 0.057 12.2 0.0 0.14 10.9 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase RIO1 PF01163.22 EKX40316.1 - 0.078 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 EKX40316.1 - 0.14 11.7 0.0 2.4 7.7 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase Lectin_C PF00059.21 EKX40317.1 - 0.058 14.1 0.0 0.13 13.0 0.0 1.6 1 0 0 1 1 1 0 Lectin C-type domain InaF-motif PF15018.6 EKX40317.1 - 5 7.1 5.9 15 5.6 5.9 1.8 1 0 0 1 1 1 0 TRP-interacting helix PDZ_6 PF17820.1 EKX40318.1 - 1.7e-09 37.4 0.2 3.5e-09 36.4 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX40318.1 - 1.1e-06 28.8 0.2 2.6e-06 27.6 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX40318.1 - 2.6e-05 24.5 0.2 6.8e-05 23.1 0.2 1.7 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX40318.1 - 0.0086 16.0 0.1 0.025 14.5 0.1 1.8 1 0 0 1 1 1 1 Tricorn protease PDZ domain Glyco_hydro_65m PF03632.15 EKX40318.1 - 0.14 10.9 0.3 0.21 10.4 0.3 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain Lipocalin_5 PF13924.6 EKX40318.1 - 0.53 10.1 2.0 5 6.9 0.1 2.5 3 0 0 3 3 3 0 Lipocalin-like domain EMP70 PF02990.16 EKX40319.1 - 2.3e-196 653.5 4.2 2.3e-196 653.5 4.2 1.7 2 0 0 2 2 2 1 Endomembrane protein 70 Flg_hook PF02120.16 EKX40320.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK TPR_12 PF13424.6 EKX40321.1 - 1.1e-18 67.2 7.7 1.7e-11 44.2 0.3 3.3 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX40321.1 - 9.7e-10 38.0 4.2 0.011 15.6 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX40321.1 - 7.3e-07 28.9 6.9 0.49 10.7 0.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX40321.1 - 1.3e-06 28.0 6.2 1.3e-06 28.0 6.2 1.4 1 1 0 1 1 1 1 MalT-like TPR region TPR_2 PF07719.17 EKX40321.1 - 8.6e-06 25.5 11.8 0.046 13.8 0.1 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX40321.1 - 0.0014 19.2 2.9 0.21 12.3 2.2 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX40321.1 - 0.1 13.4 3.6 27 5.9 0.6 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EKX40321.1 - 0.15 11.9 4.0 12 5.9 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EKX40321.1 - 0.19 11.8 7.3 33 4.8 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat ArgoMid PF16487.5 EKX40323.1 - 0.029 14.6 0.1 0.04 14.2 0.1 1.2 1 0 0 1 1 1 0 Mid domain of argonaute Ank_5 PF13857.6 EKX40325.1 - 1.4e-27 95.4 4.6 1.5e-08 34.8 0.3 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX40325.1 - 5.4e-26 91.0 0.2 3.2e-13 50.0 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX40325.1 - 1.3e-25 89.4 0.1 5.1e-10 39.7 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX40325.1 - 5.6e-22 75.5 0.2 0.00015 21.9 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 EKX40325.1 - 7.5e-22 76.8 2.4 0.00014 22.1 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Exo5 PF09810.9 EKX40326.1 - 4.6e-42 144.8 2.0 1.7e-14 54.1 0.1 3.0 1 1 2 3 3 3 3 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 EKX40326.1 - 4.7e-07 30.0 0.0 9.5e-07 29.0 0.0 1.3 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily DUF4215 PF13948.6 EKX40327.1 - 9.7e-10 38.7 1.6 9.7e-10 38.7 1.6 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF4215) Laminin_G_1 PF00054.23 EKX40327.1 - 0.076 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Laminin G domain Kelch_5 PF13854.6 EKX40328.1 - 4.3e-39 131.9 51.8 0.00041 20.3 0.2 17.1 16 0 0 16 16 16 11 Kelch motif Kelch_4 PF13418.6 EKX40328.1 - 9.5e-33 112.0 55.1 6.8e-06 26.0 0.3 15.3 15 1 0 15 15 15 8 Galactose oxidase, central domain Kelch_3 PF13415.6 EKX40328.1 - 1.3e-27 95.5 58.7 0.00011 22.4 0.1 16.8 16 0 0 16 16 16 9 Galactose oxidase, central domain Filamin PF00630.19 EKX40328.1 - 2.5e-18 66.8 0.0 9.7e-07 29.6 0.0 4.1 2 1 1 3 3 3 3 Filamin/ABP280 repeat Kelch_6 PF13964.6 EKX40328.1 - 2.2e-16 59.5 47.7 0.0007 19.8 0.3 14.4 14 1 1 15 15 15 6 Kelch motif Kelch_1 PF01344.25 EKX40328.1 - 4.8e-07 29.3 35.5 0.0011 18.5 0.5 12.3 13 1 0 13 13 13 2 Kelch motif Kelch_2 PF07646.15 EKX40328.1 - 1.4e-06 28.0 26.7 0.0027 17.6 0.2 11.0 12 0 0 12 12 12 1 Kelch motif Spc7 PF08317.11 EKX40329.1 - 0.54 9.1 10.4 0.79 8.5 10.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 EKX40329.1 - 1.1 9.3 4.6 7.5 6.6 0.7 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) PCRF PF03462.18 EKX40329.1 - 4 7.3 7.9 6.7 6.5 0.6 3.0 1 1 2 3 3 3 0 PCRF domain EF-hand_6 PF13405.6 EKX40330.1 - 0.046 13.7 0.1 0.16 12.0 0.1 2.0 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 EKX40330.1 - 0.064 13.7 0.1 0.24 11.9 0.1 2.0 1 0 0 1 1 1 0 EF-hand domain pair PLAC8 PF04749.17 EKX40332.1 - 4.3e-13 50.1 18.2 5.4e-13 49.8 18.2 1.1 1 0 0 1 1 1 1 PLAC8 family cobW PF02492.19 EKX40332.1 - 4.8 6.7 7.8 9.6 5.7 7.8 1.7 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF4440 PF14534.6 EKX40333.1 - 0.002 18.5 0.0 0.0032 17.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_3 PF13474.6 EKX40333.1 - 0.045 14.0 0.1 0.09 13.0 0.1 1.5 1 1 0 1 1 1 0 SnoaL-like domain TSC22 PF01166.18 EKX40334.1 - 0.17 12.2 1.3 0.32 11.3 1.3 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF1505 PF07403.11 EKX40335.1 - 0.01 16.0 6.8 0.01 16.0 6.8 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1505) Beta_helix PF13229.6 EKX40336.1 - 1.5e-06 28.2 0.0 0.0025 17.7 0.0 1.9 1 1 1 2 2 2 2 Right handed beta helix region NHL PF01436.21 EKX40337.1 - 2.1e-10 40.1 0.0 0.04 14.0 0.0 5.1 6 0 0 6 6 6 3 NHL repeat SGL PF08450.12 EKX40337.1 - 1.5e-06 28.0 0.0 0.017 14.7 0.0 3.3 2 2 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 EKX40337.1 - 5.9e-06 26.4 1.1 0.003 17.7 0.1 3.7 4 1 0 4 4 4 1 Arylesterase Zn_clus PF00172.18 EKX40338.1 - 4.2e-10 39.6 8.1 9.7e-10 38.4 8.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Myb_DNA-binding PF00249.31 EKX40340.1 - 7.3e-11 42.1 0.5 5.4e-10 39.3 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EKX40340.1 - 0.00023 21.0 0.2 0.00098 19.0 0.0 2.1 1 1 1 2 2 2 1 Myb DNA-binding like GAS PF13851.6 EKX40340.1 - 0.00043 19.7 4.4 0.001 18.4 4.4 1.6 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Csm1_N PF18504.1 EKX40340.1 - 0.0069 16.7 4.4 0.025 14.9 4.4 2.0 1 0 0 1 1 1 1 Csm1 N-terminal domain NEMO PF11577.8 EKX40340.1 - 0.0083 16.1 1.3 0.017 15.1 1.3 1.6 1 0 0 1 1 1 1 NF-kappa-B essential modulator NEMO ZapB PF06005.12 EKX40340.1 - 0.012 16.0 3.5 0.033 14.6 3.5 1.8 1 0 0 1 1 1 0 Cell division protein ZapB DUF4164 PF13747.6 EKX40340.1 - 0.016 15.5 0.6 0.047 14.0 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) RAP PF08373.10 EKX40341.1 - 7.9e-18 64.3 0.0 1.2e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 RAP domain MTES_1575 PF18741.1 EKX40341.1 - 5.2e-06 26.6 0.0 6.1e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 REase_MTES_1575 DUF1974 PF09317.11 EKX40342.1 - 1.7e-54 185.4 0.0 7.8e-53 179.9 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1974) Acyl-CoA_dh_N PF02771.16 EKX40342.1 - 8.4e-17 61.9 0.0 2.1e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EKX40342.1 - 6.9e-14 52.3 0.1 1.2e-13 51.6 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EKX40342.1 - 0.00032 20.9 0.0 0.00077 19.6 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain GnsAB_toxin PF08178.11 EKX40343.1 - 5.5 7.0 14.5 13 5.8 1.2 3.8 3 0 0 3 3 3 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system End3 PF12761.7 EKX40344.1 - 0.00089 19.5 12.3 0.0013 19.0 12.3 1.1 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 IKBKB_SDD PF18397.1 EKX40344.1 - 0.0062 15.9 6.7 0.0091 15.3 6.7 1.1 1 0 0 1 1 1 1 IQBAL scaffold dimerization domain APG6_N PF17675.1 EKX40344.1 - 0.037 14.5 8.6 0.058 13.9 8.6 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region NPV_P10 PF05531.12 EKX40344.1 - 0.13 12.7 2.5 4.4 7.8 0.5 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein BRE1 PF08647.11 EKX40344.1 - 0.37 10.9 14.8 0.42 10.7 3.6 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Syntaxin_2 PF14523.6 EKX40344.1 - 1 9.7 9.8 3 8.2 9.8 1.8 1 1 0 1 1 1 0 Syntaxin-like protein DUF4407 PF14362.6 EKX40344.1 - 1.1 8.6 9.1 1.7 7.9 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Csm1_N PF18504.1 EKX40344.1 - 1.3 9.4 11.7 0.15 12.5 2.7 2.8 1 1 2 3 3 3 0 Csm1 N-terminal domain Activator-TraM PF11657.8 EKX40344.1 - 1.4 8.8 5.9 2.2 8.1 5.9 1.3 1 0 0 1 1 1 0 Transcriptional activator TraM DUF948 PF06103.11 EKX40344.1 - 2 8.7 5.4 66 3.9 5.4 2.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.15 EKX40344.1 - 2.4 8.0 8.4 0.22 11.3 2.4 2.3 2 0 0 2 2 2 0 Septum formation initiator BLOC1_2 PF10046.9 EKX40344.1 - 2.5 8.5 6.0 3.9 7.8 1.3 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.9 EKX40344.1 - 3.9 6.5 12.9 5.2 6.0 12.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SlyX PF04102.12 EKX40344.1 - 5.4 7.7 10.6 0.93 10.2 4.9 2.4 1 1 1 2 2 2 0 SlyX HhH-GPD PF00730.25 EKX40345.1 - 1.2e-15 57.8 0.0 1.5e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EKX40345.1 - 2.7e-07 30.1 0.0 6.5e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EKX40345.1 - 0.14 12.8 0.1 0.35 11.5 0.0 1.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.9 EKX40345.1 - 8.8 6.8 11.3 18 5.8 11.3 1.6 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Metallophos PF00149.28 EKX40347.1 - 1.9e-32 113.4 0.1 2.8e-32 112.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EKX40347.1 - 0.011 16.1 0.1 0.062 13.7 0.1 2.1 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain DUF5378 PF17349.2 EKX40347.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Myb_DNA-binding PF00249.31 EKX40348.1 - 1.3e-06 28.4 0.0 4.8e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 Myb-like DNA-binding domain PPR_2 PF13041.6 EKX40349.1 - 3e-37 126.6 0.0 1.2e-10 41.4 0.0 4.9 1 1 4 5 5 5 5 PPR repeat family PPR_3 PF13812.6 EKX40349.1 - 3.7e-34 116.6 0.0 1.1e-11 44.7 0.0 3.3 2 1 0 3 3 3 3 Pentatricopeptide repeat domain PPR PF01535.20 EKX40349.1 - 2.4e-31 105.8 2.2 2.8e-05 24.1 0.0 6.1 6 0 0 6 6 6 6 PPR repeat PPR_1 PF12854.7 EKX40349.1 - 6.4e-25 86.5 0.0 0.00051 19.7 0.0 6.3 6 1 0 6 6 6 5 PPR repeat PPR_long PF17177.4 EKX40349.1 - 3e-18 66.0 0.0 1.4e-12 47.4 0.0 1.6 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP TPR_7 PF13176.6 EKX40349.1 - 0.055 13.5 0.1 71 3.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat RPM2 PF08579.11 EKX40349.1 - 0.095 13.1 0.0 1.2 9.5 0.0 2.4 1 1 1 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.7 EKX40349.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial ATPase expression UBD PF16455.5 EKX40350.1 - 8e-30 103.2 0.0 1.3e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 EKX40350.1 - 7.3e-10 38.5 0.0 1.2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family ADIP PF11559.8 EKX40351.1 - 0.0006 19.9 35.2 0.0022 18.1 25.3 3.4 2 1 0 2 2 2 1 Afadin- and alpha -actinin-Binding Syntaxin-6_N PF09177.11 EKX40351.1 - 0.00063 20.3 14.1 0.02 15.4 0.1 3.4 3 0 0 3 3 3 2 Syntaxin 6, N-terminal PHP PF02811.19 EKX40351.1 - 0.13 12.5 1.6 0.31 11.3 1.6 1.6 1 0 0 1 1 1 0 PHP domain Miga PF10265.9 EKX40351.1 - 1.9 7.4 15.4 0.058 12.4 8.8 1.7 2 1 0 2 2 2 0 Mitoguardin TTL PF03133.15 EKX40352.1 - 1.7e-77 260.5 0.0 3e-77 259.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EKX40352.1 - 7e-09 35.3 0.0 0.00024 20.5 0.0 3.2 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EKX40352.1 - 3.6e-06 26.4 0.0 0.046 13.0 0.0 2.5 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EKX40352.1 - 0.067 13.2 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain WD40 PF00400.32 EKX40353.1 - 7.2e-11 42.5 5.1 0.38 11.7 0.0 6.1 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX40353.1 - 4.2e-06 27.0 0.0 1.7 9.0 0.0 3.8 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DUF1132 PF06575.12 EKX40353.1 - 0.64 10.4 2.9 24 5.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1132) PTEN_C2 PF10409.9 EKX40354.1 - 0.00011 22.0 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Pkinase PF00069.25 EKX40355.1 - 1.2e-31 110.1 0.0 2.3e-31 109.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX40355.1 - 2.6e-17 63.0 0.0 3.2e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Daxx PF03344.15 EKX40355.1 - 0.0046 17.0 0.0 0.0094 16.0 0.0 1.4 1 0 0 1 1 1 1 Daxx N-terminal Rassf1C-interacting domain Haspin_kinase PF12330.8 EKX40355.1 - 0.019 13.9 0.0 0.025 13.5 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EKX40355.1 - 0.021 13.9 0.1 0.03 13.4 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 EKX40355.1 - 0.091 12.1 0.0 0.19 11.0 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Zn_clus PF00172.18 EKX40356.1 - 2.6e-14 53.0 32.4 3.1e-07 30.4 13.9 2.3 1 1 1 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3418 PF11898.8 EKX40359.1 - 0.0066 15.2 0.2 0.0078 14.9 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3418) DUF4668 PF15701.5 EKX40359.1 - 0.13 12.1 0.2 0.17 11.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) IPK PF03770.16 EKX40360.1 - 9.1e-23 81.2 0.2 1.5e-22 80.4 0.2 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase CCM2_C PF16545.5 EKX40362.1 - 0.1 13.2 0.6 0.3 11.7 0.6 1.7 1 0 0 1 1 1 0 Cerebral cavernous malformation protein, harmonin-homology Lactamase_B PF00753.27 EKX40363.1 - 2.4e-15 57.1 3.2 1.5e-13 51.2 3.2 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EKX40363.1 - 0.031 13.8 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain CAF1C_H4-bd PF12265.8 EKX40364.1 - 1.4e-16 60.5 0.0 1.6e-15 57.1 0.0 2.6 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EKX40364.1 - 3.3e-13 49.9 7.6 1e-06 29.3 0.1 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat YL1 PF05764.13 EKX40364.1 - 0.00094 19.4 8.5 0.0017 18.6 8.5 1.4 1 0 0 1 1 1 1 YL1 nuclear protein PDZ PF00595.24 EKX40365.1 - 2.2e-10 40.7 0.3 3.1e-10 40.3 0.3 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX40365.1 - 6.8e-09 35.4 0.1 1.1e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX40365.1 - 3.6e-07 30.4 0.1 5.3e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 PDZ domain Kinesin PF00225.23 EKX40366.1 - 1.4e-106 356.3 0.3 1.8e-106 355.8 0.3 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX40366.1 - 6.4e-26 91.1 0.1 1.4e-25 90.0 0.1 1.6 1 0 0 1 1 1 1 Microtubule binding Kinesin_assoc PF16183.5 EKX40366.1 - 5e-16 59.4 7.6 3e-10 40.5 0.5 3.1 2 1 1 3 3 3 2 Kinesin-associated FHA PF00498.26 EKX40366.1 - 1.9e-07 31.3 0.1 1.2e-06 28.8 0.0 2.3 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EKX40366.1 - 0.00013 22.2 0.0 0.00035 20.8 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Not3 PF04065.15 EKX40366.1 - 0.005 16.3 2.4 0.0051 16.3 0.0 2.1 3 0 0 3 3 3 1 Not1 N-terminal domain, CCR4-Not complex component YpjP PF14005.6 EKX40366.1 - 0.006 16.6 1.0 0.12 12.4 0.0 2.5 2 0 0 2 2 2 1 YpjP-like protein EH_Signature PF15611.6 EKX40366.1 - 0.014 14.8 0.2 0.049 13.1 0.1 1.8 2 0 0 2 2 2 0 EH_Signature domain HIP1_clath_bdg PF16515.5 EKX40366.1 - 1.5 9.5 8.5 0.44 11.2 4.1 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF5401 PF17380.2 EKX40366.1 - 2.4 6.1 10.9 4.3 5.3 10.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF5082 PF16888.5 EKX40366.1 - 2.6 8.4 8.0 12 6.2 2.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF1192 PF06698.11 EKX40366.1 - 3.4 7.8 5.8 1.1 9.3 0.9 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) PRKG1_interact PF15898.5 EKX40366.1 - 4.1 8.4 9.8 7.7 7.5 1.4 3.2 4 0 0 4 4 3 0 cGMP-dependent protein kinase interacting domain Fez1 PF06818.15 EKX40366.1 - 6.2 7.2 13.1 25 5.2 13.1 2.0 1 1 0 1 1 1 0 Fez1 ApoLp-III PF07464.11 EKX40368.1 - 0.00075 19.6 3.2 0.00075 19.6 3.2 4.9 3 2 1 4 4 4 2 Apolipophorin-III precursor (apoLp-III) DUF5525 PF17663.1 EKX40368.1 - 0.9 7.5 12.5 1.5 6.8 12.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5525) RNB PF00773.19 EKX40369.1 - 1e-18 67.8 0.0 1.8e-18 67.0 0.0 1.3 1 1 0 1 1 1 1 RNB domain zf-RanBP PF00641.18 EKX40369.1 - 1e-05 24.7 2.4 2e-05 23.8 2.4 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DEAD PF00270.29 EKX40370.1 - 1.9e-18 66.8 0.0 2.5e-17 63.2 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EKX40370.1 - 2.6e-12 47.1 0.0 4.3e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EKX40370.1 - 0.039 13.4 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Zot PF05707.12 EKX40370.1 - 0.12 12.0 0.1 0.58 9.8 0.0 1.9 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) DSHCT PF08148.12 EKX40371.1 - 0.0014 18.3 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 DSHCT (NUC185) domain Cellulase PF00150.18 EKX40372.1 - 1.9e-19 70.2 0.0 8.8e-13 48.3 0.0 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 EKX40372.1 - 8.4e-11 42.3 0.6 1.7e-10 41.3 0.6 1.5 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Pkinase PF00069.25 EKX40373.1 - 1.2e-74 251.0 0.0 1.6e-74 250.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX40373.1 - 1.6e-36 126.0 0.0 2.1e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX40373.1 - 0.00029 20.3 0.0 0.00053 19.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EKX40373.1 - 0.0019 17.9 0.1 0.11 12.1 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EKX40373.1 - 0.0052 15.8 0.2 0.0077 15.2 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EKX40373.1 - 0.021 14.4 0.1 0.035 13.7 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_C PF00433.24 EKX40373.1 - 0.032 14.9 0.0 0.072 13.8 0.0 1.6 1 0 0 1 1 1 0 Protein kinase C terminal domain ATG16 PF08614.11 EKX40375.1 - 0.0028 17.9 4.6 0.0028 17.9 4.6 2.0 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) ZapB PF06005.12 EKX40375.1 - 0.0032 17.9 13.4 0.083 13.3 4.5 3.1 2 1 0 2 2 2 2 Cell division protein ZapB Cep57_CLD_2 PF14197.6 EKX40375.1 - 0.013 15.6 7.9 0.89 9.7 0.5 3.5 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 TSC22 PF01166.18 EKX40375.1 - 0.02 15.2 2.4 0.033 14.5 0.1 2.6 2 1 0 2 2 2 0 TSC-22/dip/bun family YabA PF06156.13 EKX40375.1 - 0.031 14.9 6.8 0.082 13.6 0.1 2.9 1 1 1 3 3 3 0 Initiation control protein YabA NRBF2 PF08961.10 EKX40375.1 - 0.032 13.8 0.4 0.032 13.8 0.4 1.9 2 1 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator CENP-F_leu_zip PF10473.9 EKX40375.1 - 0.051 13.6 10.6 0.63 10.1 2.9 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HAP1_N PF04849.13 EKX40375.1 - 0.062 12.5 13.3 0.45 9.7 13.3 2.2 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Filament PF00038.21 EKX40375.1 - 0.067 12.8 10.2 0.076 12.6 3.6 2.6 1 1 0 3 3 3 0 Intermediate filament protein bZIP_1 PF00170.21 EKX40375.1 - 0.1 12.7 9.2 1.2 9.3 0.6 3.3 2 1 1 3 3 3 0 bZIP transcription factor Nsp1_C PF05064.13 EKX40375.1 - 0.1 12.4 2.5 0.49 10.2 1.6 2.4 2 0 0 2 2 2 0 Nsp1-like C-terminal region Mto2_bdg PF12808.7 EKX40375.1 - 0.11 12.8 8.0 0.16 12.3 0.3 3.5 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Sas6_CC PF18594.1 EKX40375.1 - 0.2 11.5 1.7 0.52 10.2 1.2 2.0 2 0 0 2 2 1 0 Sas6/XLF/XRCC4 coiled-coil domain DivIC PF04977.15 EKX40375.1 - 0.24 11.2 2.5 8.4 6.2 0.0 2.9 2 1 0 2 2 2 0 Septum formation initiator CtIP_N PF10482.9 EKX40375.1 - 0.25 11.4 11.1 3.2 7.8 0.1 3.4 3 2 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain GAS PF13851.6 EKX40375.1 - 0.28 10.5 10.0 0.27 10.6 2.3 2.7 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 EKX40375.1 - 0.3 11.5 12.1 1.9 8.9 7.2 3.0 1 1 1 2 2 2 0 Fez1 HMMR_C PF15908.5 EKX40375.1 - 0.35 11.1 7.4 1.7 8.9 0.5 3.2 2 1 2 4 4 4 0 Hyaluronan mediated motility receptor C-terminal CENP-H PF05837.12 EKX40375.1 - 0.36 11.2 12.1 0.075 13.4 1.2 3.2 1 1 2 3 3 3 0 Centromere protein H (CENP-H) FlaC_arch PF05377.11 EKX40375.1 - 1.5 9.3 5.5 11 6.5 1.6 3.2 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF16 PF01519.16 EKX40375.1 - 2.2 8.8 6.0 3.3e+02 1.8 6.0 3.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 UPF0242 PF06785.11 EKX40375.1 - 2.7 8.1 9.9 2.6 8.1 3.1 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 EKX40375.1 - 9.5 6.8 13.8 16 6.0 4.3 2.7 2 1 1 3 3 3 0 Apg6 coiled-coil region ClpS PF02617.17 EKX40376.1 - 9.5e-15 54.2 0.2 3.3e-14 52.4 0.2 2.0 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-UBR PF02207.20 EKX40376.1 - 2e-14 53.5 19.2 2e-14 53.5 19.2 2.8 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Myb_DNA-binding PF00249.31 EKX40377.1 - 3.2e-13 49.6 0.1 5.2e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX40377.1 - 0.00012 22.3 0.0 0.00025 21.2 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EKX40377.1 - 0.0032 17.3 0.2 0.0062 16.4 0.2 1.5 1 0 0 1 1 1 1 Myb DNA-binding like DUF3138 PF11336.8 EKX40377.1 - 1.9 7.0 6.4 2.6 6.5 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) GIT1_C PF12205.8 EKX40377.1 - 3.2 7.9 6.8 1.1 9.4 2.1 2.0 1 1 1 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term PDZ_6 PF17820.1 EKX40378.1 - 4.9e-11 42.3 0.9 1.1e-10 41.2 0.9 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX40378.1 - 1.1e-10 41.7 0.1 2.2e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX40378.1 - 8.9e-05 22.7 0.1 0.00016 21.9 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX40378.1 - 0.0024 17.8 0.1 0.005 16.8 0.1 1.5 1 0 0 1 1 1 1 Tricorn protease PDZ domain PUA PF01472.20 EKX40378.1 - 0.031 14.2 0.1 0.07 13.1 0.1 1.5 1 0 0 1 1 1 0 PUA domain C2 PF00168.30 EKX40378.1 - 0.067 13.5 0.0 0.48 10.7 0.0 2.3 2 0 0 2 2 2 0 C2 domain Mannosyl_trans2 PF04188.13 EKX40379.1 - 1.2e-29 103.9 8.6 2.2e-14 53.6 0.4 3.0 3 0 0 3 3 3 3 Mannosyltransferase (PIG-V) DUF1736 PF08409.11 EKX40380.1 - 1.6e-26 92.0 1.3 3.7e-26 90.9 1.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_11 PF13414.6 EKX40380.1 - 7.3e-18 64.0 3.6 2.4e-08 33.5 0.5 5.4 4 1 1 5 5 5 3 TPR repeat TPR_17 PF13431.6 EKX40380.1 - 1e-13 50.6 3.8 0.00049 20.3 0.2 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX40380.1 - 3.3e-09 36.2 6.5 0.38 10.7 0.1 6.7 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX40380.1 - 1.4e-08 34.9 0.0 3.5 8.7 0.0 6.0 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX40380.1 - 1.4e-08 34.2 4.1 0.68 10.2 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX40380.1 - 5.7e-05 23.0 1.8 6 7.3 0.1 6.1 5 1 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX40380.1 - 0.00077 19.9 2.8 2.7 8.6 0.1 4.8 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX40380.1 - 0.0033 18.0 4.7 3.6 8.3 0.0 4.8 3 1 2 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX40380.1 - 0.021 14.8 0.0 13 6.1 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TOM20_plant PF06552.12 EKX40380.1 - 0.097 12.4 0.1 1.6 8.4 0.0 2.5 1 1 1 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 DUF2048 PF09752.9 EKX40381.1 - 0.0055 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Abhydrolase domain containing 18 ubiquitin PF00240.23 EKX40381.1 - 0.012 15.3 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family Peptidase_M13_N PF05649.13 EKX40382.1 - 1.9e-71 241.8 0.0 2.6e-71 241.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 EKX40382.1 - 3.7e-67 225.9 0.0 7e-67 225.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M13 Cytochrome_CBB3 PF13442.6 EKX40383.1 - 5.1e-12 45.9 0.0 6.5e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EKX40383.1 - 1.8e-08 35.4 0.0 3.4e-08 34.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome c Cytochrom_C550 PF14495.6 EKX40383.1 - 1.4e-06 28.0 0.2 3.3e-05 23.6 0.2 2.0 1 1 0 1 1 1 1 Cytochrome c-550 domain Haem_bd PF14376.6 EKX40383.1 - 0.013 15.4 0.0 0.46 10.4 0.0 2.0 1 1 1 2 2 2 0 Haem-binding domain BEN PF10523.9 EKX40383.1 - 0.11 12.7 0.0 0.99 9.7 0.0 2.1 2 1 0 2 2 2 0 BEN domain Dehyd-heme_bind PF09098.10 EKX40383.1 - 0.13 11.8 0.0 0.79 9.3 0.0 1.9 2 0 0 2 2 2 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding Myb_Cef PF11831.8 EKX40384.1 - 7.9e-49 166.4 1.6 7.9e-49 166.4 1.6 3.7 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 EKX40384.1 - 8.3e-22 77.1 6.2 6.5e-12 45.4 1.5 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX40384.1 - 8.8e-21 73.9 6.1 7.4e-14 51.7 3.6 3.5 2 1 1 3 3 3 2 Myb-like DNA-binding domain Rap1_C PF11626.8 EKX40384.1 - 0.0031 17.6 0.0 0.34 11.0 0.2 3.2 3 1 0 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain FAM193_C PF15914.5 EKX40384.1 - 0.45 10.3 3.4 1.1 9.1 0.3 2.8 2 0 0 2 2 2 0 FAM193 family C-terminal DUF726 PF05277.12 EKX40385.1 - 3.5e-71 239.9 0.0 3.9e-71 239.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF726) BTRD1 PF17660.1 EKX40385.1 - 0.43 10.4 1.5 5 7.0 0.1 2.4 2 0 0 2 2 2 0 Bacterial tandem repeat domain 1 PX PF00787.24 EKX40386.1 - 1.4e-19 70.2 0.2 1.9e-19 69.7 0.2 1.1 1 0 0 1 1 1 1 PX domain Ank_4 PF13637.6 EKX40387.1 - 4.6e-25 87.7 0.1 1.5e-10 41.4 0.0 5.6 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX40387.1 - 3.8e-21 75.5 0.0 7.5e-11 42.5 0.0 4.1 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX40387.1 - 1.7e-15 55.6 0.3 4.7e-05 23.5 0.0 6.6 6 1 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 EKX40387.1 - 6.8e-15 54.8 0.1 1.2e-06 28.7 0.0 5.6 5 1 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EKX40387.1 - 7.3e-14 51.7 0.3 1.3e-08 34.9 0.1 5.2 5 1 1 6 6 6 2 Ankyrin repeats (many copies) LAP1C PF05609.12 EKX40388.1 - 9 5.3 24.7 9.4 5.2 24.7 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Coatomer_WDAD PF04053.14 EKX40389.1 - 3e-160 534.1 0.0 8.4e-160 532.6 0.0 1.7 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 EKX40389.1 - 1.9e-40 136.1 12.5 2.4e-07 31.3 0.0 8.4 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX40389.1 - 4.9e-08 33.2 0.6 0.14 12.5 0.0 6.2 3 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EKX40389.1 - 0.00054 20.0 0.1 5.9 7.0 0.0 4.4 3 2 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.11 EKX40389.1 - 0.029 13.1 0.0 4.5 5.9 0.0 3.1 2 1 1 3 3 3 0 Nup133 N terminal like TPR_1 PF00515.28 EKX40389.1 - 0.051 13.4 0.0 0.22 11.4 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX40389.1 - 0.066 14.1 1.7 6.4 7.9 0.1 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat Ge1_WD40 PF16529.5 EKX40389.1 - 0.12 11.4 4.5 3.7 6.4 0.1 3.5 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Arm PF00514.23 EKX40390.1 - 2.1e-12 46.6 0.0 0.00011 22.1 0.1 5.2 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EKX40390.1 - 4.3e-08 33.1 0.0 0.5 10.4 0.0 4.3 1 1 4 5 5 5 5 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 EKX40390.1 - 0.0031 17.9 13.8 2.7 8.4 10.5 4.1 1 1 1 2 2 2 1 HEAT repeats WAPL PF07814.13 EKX40390.1 - 0.0054 15.6 0.7 0.13 11.0 0.3 3.2 1 1 0 2 2 2 1 Wings apart-like protein regulation of heterochromatin Pro-NT_NN PF07421.11 EKX40390.1 - 0.075 13.3 0.1 0.15 12.3 0.1 1.6 1 1 0 1 1 1 0 Neurotensin/neuromedin N precursor Pkinase_Tyr PF07714.17 EKX40391.1 - 2.4e-38 131.9 0.0 2.6e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX40391.1 - 4.2e-15 55.8 0.0 4.7e-15 55.7 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain U-box PF04564.15 EKX40392.1 - 5.9e-19 68.0 0.0 6.9e-19 67.8 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX40392.1 - 0.00018 21.3 0.0 0.00025 20.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EKX40392.1 - 0.00028 20.9 0.1 0.00043 20.2 0.1 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-NOSIP PF15906.5 EKX40392.1 - 0.055 13.6 0.0 0.068 13.3 0.0 1.2 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Pkinase_Tyr PF07714.17 EKX40393.1 - 5.7e-55 186.4 0.0 6.9e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX40393.1 - 1.4e-22 80.4 0.0 1.8e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 EKX40394.1 - 2.9e-35 119.7 10.2 1.2e-08 35.5 0.8 4.0 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.8 EKX40394.1 - 1.2e-06 27.5 4.8 0.86 8.2 0.1 4.0 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EKX40394.1 - 4.7e-06 25.4 0.7 0.00093 17.8 0.1 2.0 1 1 1 2 2 2 2 Cytochrome D1 heme domain WD40_like PF17005.5 EKX40394.1 - 2.3e-05 23.9 0.0 0.28 10.5 0.0 3.4 1 1 2 3 3 3 2 WD40-like domain Nbas_N PF15492.6 EKX40394.1 - 0.00014 21.3 1.3 0.11 11.8 0.0 3.1 1 1 2 3 3 3 1 Neuroblastoma-amplified sequence, N terminal VID27 PF08553.10 EKX40394.1 - 0.00019 20.6 0.9 0.029 13.4 0.1 2.0 1 1 1 2 2 2 2 VID27 C-terminal WD40-like domain Ge1_WD40 PF16529.5 EKX40394.1 - 0.0037 16.3 0.6 1.3 7.9 0.0 3.2 1 1 3 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EKX40394.1 - 0.011 14.5 0.3 2.7 6.7 0.1 2.5 1 1 1 2 2 2 0 Nup133 N terminal like OCD_Mu_crystall PF02423.15 EKX40394.1 - 0.056 12.4 0.0 3.4 6.5 0.0 2.7 2 1 1 3 3 3 0 Ornithine cyclodeaminase/mu-crystallin family FG-GAP_2 PF14312.6 EKX40394.1 - 0.075 13.3 6.6 7.2 6.9 0.2 3.9 4 0 0 4 4 4 0 FG-GAP repeat PALB2_WD40 PF16756.5 EKX40394.1 - 0.14 11.0 4.9 0.16 10.9 0.4 2.3 1 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain DUF4774 PF15999.5 EKX40394.1 - 0.59 10.0 1.8 55 3.7 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4774) RibD_C PF01872.17 EKX40394.1 - 4.4 7.1 7.8 14 5.5 0.2 3.5 2 1 2 4 4 4 0 RibD C-terminal domain Myosin_head PF00063.21 EKX40396.1 - 1.7e-181 604.9 4.7 2.1e-180 601.3 4.7 1.9 1 1 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 EKX40396.1 - 0.0036 17.7 0.5 0.038 14.4 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EKX40396.1 - 0.0089 16.3 0.2 0.065 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain CSN8_PSD8_EIF3K PF10075.9 EKX40397.1 - 5.8e-23 81.5 0.0 8.8e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 EKX40397.1 - 6.1e-05 22.6 0.0 8.1e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP family DEK_C PF08766.11 EKX40398.1 - 1.4e-06 28.1 1.0 3e-06 27.0 1.0 1.5 1 0 0 1 1 1 1 DEK C terminal domain Stealth_CR1 PF17101.5 EKX40398.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Stealth protein CR1, conserved region 1 Acyltransferase PF01553.21 EKX40399.1 - 5.1e-08 32.6 0.0 1.6e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Acyltransferase HemY_N PF07219.13 EKX40399.1 - 0.11 12.7 0.2 0.11 12.7 0.2 2.2 2 0 0 2 2 2 0 HemY protein N-terminus PAS_9 PF13426.7 EKX40400.1 - 9.6e-08 32.2 0.0 3.5e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EKX40400.1 - 2.6e-07 30.6 0.2 8e-07 29.0 0.0 1.8 2 1 0 2 2 2 1 PAS fold HLH PF00010.26 EKX40400.1 - 1.9e-06 27.8 0.4 3.3e-06 26.9 0.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_8 PF13188.7 EKX40400.1 - 0.00039 20.4 0.0 0.00093 19.2 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 EKX40400.1 - 0.00047 20.4 0.0 0.0014 18.9 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 EKX40400.1 - 0.0013 19.0 0.0 0.0022 18.2 0.0 1.4 1 0 0 1 1 1 1 PAS fold Amdo_NSP PF12475.8 EKX40401.1 - 0.058 13.5 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Amdovirus non-structural protein Ribonuc_2-5A PF06479.12 EKX40402.1 - 0.015 15.5 2.8 0.25 11.5 0.3 2.8 2 0 0 2 2 2 0 Ribonuclease 2-5A Peptidase_M22 PF00814.25 EKX40405.1 - 4.4e-72 243.0 0.2 5.3e-72 242.8 0.2 1.1 1 0 0 1 1 1 1 Glycoprotease family PK_C PF02887.16 EKX40405.1 - 0.0055 16.9 0.1 3.1 8.0 0.0 2.3 2 0 0 2 2 2 2 Pyruvate kinase, alpha/beta domain Methyltransf_2 PF00891.18 EKX40405.1 - 0.088 12.1 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 O-methyltransferase domain TIG PF01833.24 EKX40407.1 - 4.9e-147 478.4 87.1 1.9e-10 40.7 1.6 26.0 26 0 0 26 26 26 23 IPT/TIG domain TIG_plexin PF17960.1 EKX40407.1 - 1.9e-11 43.8 20.0 0.54 10.3 0.0 14.2 16 0 0 16 16 16 3 TIG domain Qn_am_d_aIII PF09099.10 EKX40407.1 - 6e-05 23.3 0.1 2.8 8.4 0.0 6.3 8 0 0 8 8 8 2 Quinohemoprotein amine dehydrogenase, alpha subunit domain III TIG PF01833.24 EKX40408.1 - 5e-111 363.0 70.5 7.3e-10 38.8 0.1 25.4 25 1 0 25 25 25 21 IPT/TIG domain TIG_plexin PF17960.1 EKX40408.1 - 8.6e-18 64.1 16.9 0.11 12.5 0.0 14.6 19 0 0 19 19 19 6 TIG domain TIG PF01833.24 EKX40409.1 - 4.8e-167 542.5 123.1 1.2e-12 47.7 2.4 32.3 33 0 0 33 33 33 28 IPT/TIG domain TIG_plexin PF17960.1 EKX40409.1 - 1.3e-25 89.2 18.2 0.0017 18.3 0.0 16.2 17 0 0 17 17 17 9 TIG domain Qn_am_d_aIII PF09099.10 EKX40409.1 - 2.9e-06 27.6 0.5 1.6 9.2 0.0 8.8 10 0 0 10 10 10 1 Quinohemoprotein amine dehydrogenase, alpha subunit domain III TIG PF01833.24 EKX40410.1 - 8.7e-10 38.5 0.2 9.4e-10 38.4 0.2 1.0 1 0 0 1 1 1 1 IPT/TIG domain TIG_plexin PF17960.1 EKX40410.1 - 0.012 15.6 0.0 0.012 15.6 0.0 1.3 1 1 0 1 1 1 0 TIG domain NARP1 PF12569.8 EKX40411.1 - 4.8e-183 609.8 7.8 4.8e-183 609.8 7.8 2.3 3 0 0 3 3 3 1 NMDA receptor-regulated protein 1 TPR_19 PF14559.6 EKX40411.1 - 3.4e-15 56.3 14.1 0.00027 21.4 0.1 6.1 4 1 2 7 7 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 EKX40411.1 - 1e-14 53.9 8.2 0.0076 17.0 0.3 8.0 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX40411.1 - 5.5e-14 51.1 21.3 1.5e-05 24.8 0.2 8.3 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 EKX40411.1 - 4.6e-12 46.4 4.3 0.055 14.1 0.4 5.9 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX40411.1 - 7.2e-11 41.3 7.8 5.8e-05 22.8 0.2 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX40411.1 - 7.3e-11 41.4 11.5 4.2e-05 23.4 0.1 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX40411.1 - 1.2e-10 40.7 17.7 3.3e-05 23.5 0.4 7.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX40411.1 - 5.4e-09 35.8 6.4 0.56 10.7 0.0 7.7 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX40411.1 - 5.2e-08 33.1 14.9 0.028 14.7 0.3 6.5 4 3 1 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 EKX40411.1 - 1.6e-06 27.6 0.9 0.028 13.7 0.0 3.6 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 EKX40411.1 - 3.2e-06 27.2 1.0 0.11 13.2 0.2 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX40411.1 - 9.6e-06 25.2 7.5 0.0009 18.9 0.1 4.0 5 0 0 5 5 3 2 TPR repeat TPR_9 PF13371.6 EKX40411.1 - 5.4e-05 23.3 0.8 0.088 13.0 0.0 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX40411.1 - 0.00049 20.3 18.6 0.12 12.6 0.2 5.8 4 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EKX40411.1 - 0.00069 19.1 1.3 0.023 14.1 0.3 2.9 3 0 0 3 3 3 1 MalT-like TPR region TPR_6 PF13174.6 EKX40411.1 - 0.0041 17.7 11.6 9.8 7.1 0.2 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX40411.1 - 0.005 16.7 6.0 2.1 8.3 0.3 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX40411.1 - 0.13 12.3 7.3 23 5.2 0.1 4.6 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Pex14_N PF04695.13 EKX40411.1 - 0.19 12.4 1.4 0.35 11.5 1.4 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MIT PF04212.18 EKX40411.1 - 0.29 11.2 5.2 1.6 8.9 0.2 4.1 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain Rrn6 PF10214.9 EKX40411.1 - 0.85 8.0 2.2 0.61 8.5 0.5 1.5 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor DHC_N1 PF08385.12 EKX40412.1 - 7.1e-164 546.5 11.1 7.1e-164 546.5 11.1 4.4 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 EKX40412.1 - 8e-157 521.3 1.0 9.6e-156 517.8 0.0 3.3 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EKX40412.1 - 5.1e-125 417.7 10.2 5.1e-125 417.7 10.2 6.2 7 1 0 7 7 7 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EKX40412.1 - 3.5e-102 341.2 0.0 1.2e-101 339.4 0.0 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EKX40412.1 - 3.4e-85 284.6 0.7 3.4e-84 281.4 0.1 3.2 2 0 0 2 2 2 1 ATP-binding dynein motor region Dynein_C PF18199.1 EKX40412.1 - 8.2e-80 268.3 0.1 1.9e-78 263.8 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 EKX40412.1 - 6.2e-70 234.4 0.4 7.2e-64 214.6 0.0 3.8 3 0 0 3 3 3 2 P-loop containing dynein motor region MT PF12777.7 EKX40412.1 - 9.3e-62 209.0 13.6 2.5e-61 207.7 13.6 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 EKX40412.1 - 9.4e-53 178.4 0.2 3e-52 176.7 0.2 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EKX40412.1 - 3.8e-41 139.9 0.0 3.4e-40 136.8 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EKX40412.1 - 1e-18 67.7 0.1 9.2e-18 64.6 0.0 3.0 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EKX40412.1 - 3.2e-18 65.8 1.6 3.6e-17 62.4 0.0 3.5 3 0 0 3 3 2 1 AAA+ lid domain AAA_5 PF07728.14 EKX40412.1 - 7.2e-18 64.9 0.0 3e-05 24.0 0.0 5.6 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EKX40412.1 - 2e-06 28.1 3.3 4.2 7.6 0.0 6.1 5 1 0 5 5 4 2 AAA domain AAA PF00004.29 EKX40412.1 - 6.3e-06 26.6 0.1 0.19 12.2 0.0 5.5 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX40412.1 - 1.7e-05 25.2 2.9 5.7 7.3 0.0 6.4 5 2 1 7 7 6 1 AAA ATPase domain DUF853 PF05872.12 EKX40412.1 - 0.00034 19.3 1.0 0.8 8.2 0.1 3.5 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF853) AAA_18 PF13238.6 EKX40412.1 - 0.0015 19.0 0.0 0.59 10.7 0.0 4.2 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EKX40412.1 - 0.0053 16.5 4.2 1.7 8.3 0.1 4.0 4 0 0 4 4 4 1 AAA domain RsgA_GTPase PF03193.16 EKX40412.1 - 0.011 15.7 0.1 0.12 12.2 0.0 2.8 2 0 0 2 2 2 0 RsgA GTPase T2SSE PF00437.20 EKX40412.1 - 0.034 13.2 0.9 2.6 7.0 0.1 3.3 3 0 0 3 3 3 0 Type II/IV secretion system protein DUF1999 PF09390.10 EKX40412.1 - 0.13 11.9 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1999) Nsp1_C PF05064.13 EKX40412.1 - 2.5 8.0 17.5 2.4 8.0 5.3 4.2 3 0 0 3 3 3 0 Nsp1-like C-terminal region HMMR_N PF15905.5 EKX40412.1 - 2.5 7.5 33.4 0.039 13.4 13.3 3.3 3 0 0 3 3 2 0 Hyaluronan mediated motility receptor N-terminal CALCOCO1 PF07888.11 EKX40412.1 - 3.9 6.2 30.9 0.0068 15.3 4.6 3.1 3 0 0 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like Thioredoxin PF00085.20 EKX40413.1 - 1e-57 192.5 0.0 2.5e-29 101.3 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 EKX40413.1 - 8.3e-11 42.3 0.9 0.00026 21.4 0.1 4.3 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_6 PF13848.6 EKX40413.1 - 1.3e-10 41.5 0.0 5.6e-05 23.1 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EKX40413.1 - 7.9e-07 28.9 0.0 0.00094 19.0 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.6 EKX40413.1 - 3.1e-06 27.4 0.1 0.12 12.8 0.0 4.3 2 2 2 4 4 4 1 Thioredoxin-like Thioredoxin_7 PF13899.6 EKX40413.1 - 5.7e-06 26.4 0.0 0.022 14.9 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin-like TraF PF13728.6 EKX40413.1 - 7.8e-06 25.9 0.0 0.0053 16.6 0.0 3.0 3 0 0 3 3 3 2 F plasmid transfer operon protein OST3_OST6 PF04756.13 EKX40413.1 - 1.9e-05 24.2 0.0 0.098 12.0 0.0 2.2 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family ERp29_N PF07912.13 EKX40413.1 - 0.0025 17.9 0.0 1.3 9.2 0.0 2.3 2 0 0 2 2 2 2 ERp29, N-terminal domain Thioredoxin_3 PF13192.6 EKX40413.1 - 0.005 16.9 0.0 0.94 9.6 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin domain Glutaredoxin PF00462.24 EKX40413.1 - 0.012 15.8 0.4 7.7 6.8 0.0 2.7 2 1 0 2 2 2 0 Glutaredoxin Thioredoxin_5 PF13743.6 EKX40413.1 - 0.042 13.5 0.0 20 4.8 0.0 3.6 2 2 1 3 3 3 0 Thioredoxin LRR_8 PF13855.6 EKX40414.1 - 7.3e-08 32.1 8.1 5.7e-05 22.8 0.3 3.1 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EKX40414.1 - 7.8e-08 32.5 9.1 0.00023 21.5 0.3 3.4 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EKX40414.1 - 0.0033 17.4 4.9 0.76 10.0 0.0 4.3 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.33 EKX40414.1 - 0.0041 17.5 9.5 1 10.1 0.0 5.4 5 1 0 5 5 5 1 Leucine Rich Repeat LRR_8 PF13855.6 EKX40415.1 - 7.9e-64 211.3 99.3 4.3e-09 36.0 4.0 11.7 5 2 6 12 12 12 12 Leucine rich repeat LRR_4 PF12799.7 EKX40415.1 - 7.4e-47 156.5 121.5 3.1e-06 27.4 2.2 14.8 9 3 8 17 17 17 17 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX40415.1 - 1.5e-08 34.3 56.8 1.6e-07 31.0 5.2 7.8 1 1 4 7 7 7 4 Leucine-rich repeat LRR_1 PF00560.33 EKX40415.1 - 8.9e-07 28.6 97.1 1.2 10.0 0.3 20.4 21 2 0 21 21 21 6 Leucine Rich Repeat LRR_5 PF13306.6 EKX40415.1 - 0.00011 22.2 22.1 0.1 12.6 2.4 5.3 3 3 2 5 5 5 4 BspA type Leucine rich repeat region (6 copies) RsmF_methylt_CI PF17126.5 EKX40415.1 - 0.00013 21.9 0.7 1.6 8.8 0.0 5.5 4 2 0 5 5 5 1 RsmF rRNA methyltransferase first C-terminal domain LRR_6 PF13516.6 EKX40415.1 - 0.16 12.1 88.7 3.9 7.8 0.7 16.5 17 0 0 17 17 17 0 Leucine Rich repeat TPR_19 PF14559.6 EKX40416.1 - 7e-28 96.9 10.2 0.00022 21.7 1.7 10.8 8 3 3 11 11 11 6 Tetratricopeptide repeat TPR_1 PF00515.28 EKX40416.1 - 4.5e-23 80.0 23.2 0.0047 16.7 0.1 13.7 14 0 0 14 14 14 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX40416.1 - 7.7e-23 79.2 19.3 0.00022 21.8 0.1 14.4 9 4 7 16 16 15 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX40416.1 - 4.2e-22 76.4 31.3 0.0018 18.3 0.2 14.0 16 0 0 16 16 15 5 Tetratricopeptide repeat TPR_17 PF13431.6 EKX40416.1 - 2e-18 65.4 12.2 0.36 11.3 0.1 12.0 13 0 0 13 13 11 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX40416.1 - 3.8e-17 61.7 13.3 0.001 18.7 0.2 11.9 12 2 2 14 14 13 3 TPR repeat TPR_12 PF13424.6 EKX40416.1 - 3.3e-16 59.3 22.9 0.02 15.2 1.5 9.3 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 EKX40416.1 - 5.3e-14 52.6 24.5 2.1e-06 28.3 0.6 7.4 9 0 0 9 9 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 EKX40416.1 - 3.4e-13 48.7 28.0 0.093 13.0 1.2 12.0 15 0 0 15 15 13 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX40416.1 - 2e-12 46.2 15.2 0.023 14.7 0.1 9.1 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 EKX40416.1 - 1.1e-11 44.7 5.0 0.061 13.5 0.0 6.9 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_15 PF13429.6 EKX40416.1 - 3.6e-10 39.5 8.6 1.2e-05 24.7 0.7 5.3 3 1 2 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX40416.1 - 1.1e-07 32.0 15.5 0.94 10.2 0.0 10.2 12 0 0 12 12 9 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX40416.1 - 9e-07 29.0 19.1 0.053 13.7 0.0 5.7 6 1 1 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 DUF2225 PF09986.9 EKX40416.1 - 8.7e-05 22.3 0.1 1.1 9.0 0.0 3.8 2 2 1 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_20 PF14561.6 EKX40416.1 - 0.0003 21.1 0.7 0.61 10.5 0.6 4.8 3 2 2 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX40416.1 - 0.0015 18.6 8.1 2.2 8.4 0.0 7.3 10 1 1 11 11 8 1 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 EKX40416.1 - 0.0046 17.5 0.2 2.9 8.8 0.1 4.6 4 0 0 4 4 3 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EKX40416.1 - 0.016 14.9 0.4 4.5 6.9 0.0 4.1 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF627 PF04781.12 EKX40416.1 - 0.02 14.9 2.3 7.1 6.7 0.0 4.3 3 3 2 5 5 5 0 Protein of unknown function (DUF627) TPR_10 PF13374.6 EKX40416.1 - 0.15 12.0 20.9 1.9 8.5 0.0 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EKX40416.1 - 0.21 11.6 1.1 9.2 6.3 0.1 3.5 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 PrmC_N PF17827.1 EKX40416.1 - 0.42 11.2 2.9 3.3 8.4 0.0 3.7 5 0 0 5 5 3 0 PrmC N-terminal domain MIT PF04212.18 EKX40416.1 - 0.9 9.7 9.4 8.3 6.6 0.1 5.6 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain EF-hand_6 PF13405.6 EKX40418.1 - 2.8e-08 33.0 4.2 3.8e-06 26.4 0.1 3.7 2 1 1 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 EKX40418.1 - 9e-06 24.9 1.5 0.00028 20.2 0.0 3.2 4 0 0 4 4 4 1 EF hand EF-hand_7 PF13499.6 EKX40418.1 - 1.1e-05 25.8 3.9 0.0012 19.3 3.9 2.3 1 1 0 1 1 1 1 EF-hand domain pair CNOT1_TTP_bind PF16417.5 EKX40418.1 - 0.082 12.1 0.3 0.16 11.1 0.1 1.5 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 1 TTP binding domain EF-hand_5 PF13202.6 EKX40418.1 - 0.13 11.9 0.0 0.13 11.9 0.0 2.7 4 0 0 4 4 4 0 EF hand IF2_N PF04760.15 EKX40418.1 - 0.16 11.8 1.0 2.3 8.1 0.0 2.9 4 0 0 4 4 4 0 Translation initiation factor IF-2, N-terminal region Atx10homo_assoc PF09759.9 EKX40419.1 - 8.1e-13 48.2 3.2 9e-05 22.4 0.1 4.1 2 2 4 6 6 6 5 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 EKX40419.1 - 2e-09 37.1 12.0 0.018 15.0 0.0 6.5 7 1 0 7 7 7 4 Armadillo/beta-catenin-like repeat RICTOR_N PF14664.6 EKX40419.1 - 0.013 14.6 0.0 1 8.3 0.0 2.1 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term DnaJ_CXXCXGXG PF00684.19 EKX40420.1 - 7.2 7.1 55.1 9.1 6.7 9.4 3.6 1 1 2 3 3 3 0 DnaJ central domain Exo_endo_phos PF03372.23 EKX40421.1 - 5.6e-06 26.0 0.2 0.036 13.6 0.0 2.5 1 1 1 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Bud13 PF09736.9 EKX40422.1 - 2.4e-42 144.8 7.8 2.4e-42 144.8 7.8 2.2 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex EURL PF06937.11 EKX40422.1 - 0.099 12.0 1.4 0.16 11.4 1.4 1.4 1 0 0 1 1 1 0 EURL protein Spt20 PF12090.8 EKX40423.1 - 0.011 15.4 3.6 0.018 14.7 3.6 1.3 1 0 0 1 1 1 0 Spt20 family Trypan_PARP PF05887.11 EKX40423.1 - 1.6 8.7 5.4 2.5 8.1 5.4 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Cadherin_4 PF17803.1 EKX40424.1 - 0.002 18.7 0.2 0.002 18.7 0.2 6.0 5 1 0 5 5 5 1 Bacterial cadherin-like domain Halogen_Hydrol PF10112.9 EKX40424.1 - 2.9 7.9 6.6 0.37 10.8 0.1 2.6 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Big_9 PF17963.1 EKX40424.1 - 7.3 7.4 18.1 4.2 8.2 0.0 7.1 7 1 0 7 7 7 0 Bacterial Ig domain F5_F8_type_C PF00754.25 EKX40425.1 - 2.9e-08 33.9 0.1 7.5e-08 32.5 0.1 1.7 1 0 0 1 1 1 1 F5/8 type C domain EF-hand_1 PF00036.32 EKX40427.1 - 4.4e-12 44.6 4.3 4.5e-06 25.8 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EKX40427.1 - 3e-10 39.2 0.5 0.0033 17.2 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain MIB_HERC2 PF06701.13 EKX40427.1 - 3.4e-10 40.0 6.1 7.7e-10 38.9 5.4 2.1 2 1 0 2 2 2 1 Mib_herc2 EF-hand_7 PF13499.6 EKX40427.1 - 1.8e-08 34.7 3.0 6.3e-07 29.8 1.6 2.5 1 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 EKX40427.1 - 1.3e-06 28.2 4.4 0.0011 18.7 0.3 3.4 2 2 1 3 3 3 2 EF-hand domain pair RPN7 PF10602.9 EKX40427.1 - 0.00014 21.7 0.1 0.00023 20.9 0.1 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 EF-hand_5 PF13202.6 EKX40427.1 - 0.00061 19.2 0.8 0.01 15.3 0.1 2.6 2 0 0 2 2 2 1 EF hand Mob_Pre PF01076.19 EKX40427.1 - 0.057 13.2 0.9 0.1 12.4 0.9 1.3 1 0 0 1 1 1 0 Plasmid recombination enzyme PT PF04886.12 EKX40428.1 - 2.8 7.6 9.6 19 4.9 3.7 2.5 1 1 1 2 2 2 0 PT repeat Carb_anhydrase PF00194.21 EKX40429.1 - 6.6e-18 65.2 0.4 7.2e-10 38.8 0.1 2.2 1 1 1 2 2 2 2 Eukaryotic-type carbonic anhydrase Pkinase PF00069.25 EKX40430.1 - 3.7e-21 75.7 0.0 5.1e-21 75.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX40430.1 - 2.5e-17 63.1 0.0 2.9e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX40430.1 - 1.1e-06 27.7 0.0 1.3e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX40430.1 - 0.013 15.5 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EKX40430.1 - 0.036 13.1 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 EKX40430.1 - 0.11 11.4 0.0 0.38 9.7 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase PF00069.25 EKX40431.1 - 1.1e-38 133.2 0.0 1.2e-38 133.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX40431.1 - 1.5e-36 126.1 0.0 1.6e-36 125.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX40431.1 - 6.4e-07 28.5 0.0 8.9e-07 28.0 0.0 1.2 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EKX40431.1 - 5.5e-05 22.6 0.1 0.00051 19.5 0.0 1.9 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX40431.1 - 0.0095 15.9 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EKX40431.1 - 0.013 14.6 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 EKX40431.1 - 0.029 14.0 0.0 0.037 13.7 0.0 1.4 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Gelsolin PF00626.22 EKX40432.1 - 3.2e-22 78.2 0.0 1.4e-12 47.3 0.0 4.3 3 1 1 4 4 4 3 Gelsolin repeat VHP PF02209.19 EKX40432.1 - 8.1e-16 57.8 0.2 1.9e-15 56.6 0.2 1.7 1 0 0 1 1 1 1 Villin headpiece domain Nop14 PF04147.12 EKX40432.1 - 0.055 11.7 11.3 0.072 11.3 11.3 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 EKX40432.1 - 0.28 10.9 5.4 0.56 9.9 5.4 1.5 1 0 0 1 1 1 0 FAM176 family PGA2 PF07543.12 EKX40432.1 - 0.59 10.1 9.7 1.2 9.1 9.7 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 CDC45 PF02724.14 EKX40432.1 - 0.77 8.0 8.6 0.98 7.6 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 EKX40432.1 - 1.2 8.4 13.5 2.2 7.5 13.5 1.4 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 EKX40432.1 - 8 6.6 21.3 13 6.0 21.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Cg6151-P PF10233.9 EKX40433.1 - 0.0098 16.2 1.9 0.063 13.6 0.2 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein CG6151-P Acyl_transf_3 PF01757.22 EKX40433.1 - 0.012 14.7 0.9 0.016 14.3 0.9 1.1 1 0 0 1 1 1 0 Acyltransferase family Rhomboid PF01694.22 EKX40433.1 - 0.026 14.5 0.6 0.039 13.9 0.6 1.3 1 0 0 1 1 1 0 Rhomboid family G0-G1_switch_2 PF15103.6 EKX40434.1 - 0.1 13.0 0.8 1.7 9.1 0.0 2.4 2 0 0 2 2 2 0 G0/G1 switch protein 2 FtsX PF02687.21 EKX40434.1 - 2.4 8.7 14.6 0.72 10.4 2.9 3.1 3 0 0 3 3 3 0 FtsX-like permease family Phage_holin_3_6 PF07332.11 EKX40434.1 - 4.3 7.4 12.1 0.86 9.7 2.7 2.5 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4234 PF14018.6 EKX40434.1 - 7.7 6.7 12.4 0.21 11.7 1.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4234) Ank_5 PF13857.6 EKX40435.1 - 4.9e-05 23.5 0.1 0.043 14.2 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX40435.1 - 0.00014 22.3 0.0 0.00022 21.7 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX40435.1 - 0.002 18.7 0.0 0.0022 18.6 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX40435.1 - 0.014 15.8 0.0 3.2 8.6 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat CRAL_TRIO PF00650.20 EKX40436.1 - 5.4e-36 123.7 0.0 8e-36 123.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EKX40436.1 - 8.7e-07 29.2 0.0 1.4e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EKX40436.1 - 2.7e-06 27.5 0.1 6.4e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF257 PF03192.13 EKX40436.1 - 0.067 13.0 0.0 0.1 12.4 0.0 1.3 1 1 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 Myb_DNA-binding PF00249.31 EKX40438.1 - 4.2e-10 39.7 0.1 1.2e-09 38.2 0.1 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain TPR_19 PF14559.6 EKX40439.1 - 5.1e-05 23.7 2.2 0.00061 20.3 0.3 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX40439.1 - 0.00031 20.6 4.5 0.053 13.7 0.9 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 EKX40439.1 - 0.0006 20.1 0.3 0.0017 18.6 0.3 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX40439.1 - 0.0068 17.1 8.0 0.045 14.6 1.2 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 EKX40439.1 - 0.013 14.7 0.6 0.021 14.0 0.6 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 EKX40439.1 - 0.028 14.8 0.2 20 5.9 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EKX40439.1 - 0.061 13.2 0.2 1.8 8.6 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EKX40439.1 - 0.061 14.0 7.1 0.13 13.0 1.9 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EKX40439.1 - 0.088 12.5 0.1 31 4.4 0.0 3.1 3 0 0 3 3 3 0 TPR repeat TPR_12 PF13424.6 EKX40439.1 - 0.11 12.8 6.8 6.5 7.1 0.2 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX40439.1 - 0.55 10.6 2.4 15 6.1 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.32 EKX40441.1 - 1.6e-56 187.0 8.5 7.4e-10 39.3 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX40441.1 - 1.2e-19 70.4 0.0 0.00062 20.0 0.0 5.8 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX40441.1 - 3.3e-12 46.0 4.4 0.0039 16.2 2.2 5.9 1 1 4 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EKX40441.1 - 1.8e-05 24.5 0.0 1.4 9.0 0.0 3.9 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat WD40_like PF17005.5 EKX40441.1 - 0.00018 21.0 0.0 0.018 14.4 0.0 3.2 4 0 0 4 4 4 1 WD40-like domain Nbas_N PF15492.6 EKX40441.1 - 0.0014 18.0 1.0 12 5.1 0.0 4.2 2 1 3 5 5 5 2 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.9 EKX40441.1 - 0.026 14.2 3.7 19 5.1 0.1 3.9 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature ELYS-bb PF16687.5 EKX40441.1 - 0.034 12.7 0.0 0.2 10.2 0.0 2.0 1 1 1 2 2 2 0 beta-propeller of ELYS nucleoporin TFIIIC_delta PF12657.7 EKX40441.1 - 0.084 12.8 0.1 15 5.5 0.0 3.2 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Ret2_MD PF18528.1 EKX40441.1 - 0.21 12.0 0.0 29 5.1 0.0 3.7 2 2 3 5 5 5 0 RNA editing 3' terminal uridylyl transferase 2 middle domain DUF1664 PF07889.12 EKX40442.1 - 0.21 11.6 0.7 0.37 10.8 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Toxin_35 PF10530.9 EKX40443.1 - 0.00055 19.9 26.9 0.35 10.9 1.8 4.7 1 1 4 5 5 5 5 Toxin with inhibitor cystine knot ICK or Knottin scaffold Myotoxins PF00819.17 EKX40443.1 - 0.066 13.5 20.7 1.1 9.6 1.8 5.1 1 1 3 4 4 4 0 Myotoxin, crotamine Defensin_beta PF00711.19 EKX40443.1 - 0.46 10.6 21.1 47 4.1 0.1 6.5 2 2 4 6 6 6 0 Beta defensin Toxin_30 PF08117.11 EKX40443.1 - 4.3 7.7 24.5 5.3 7.4 1.2 4.2 1 1 3 4 4 4 0 Ptu family UL17 PF17640.2 EKX40443.1 - 5.8 7.0 18.2 8.8 6.4 1.1 3.6 1 1 1 2 2 2 0 Uncharacterized UL17 EamA PF00892.20 EKX40444.1 - 7.1e-17 61.9 22.7 5.5e-11 42.8 9.2 2.6 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EKX40444.1 - 0.0015 18.0 1.8 0.0015 18.0 1.8 2.0 2 1 1 3 3 3 1 Triose-phosphate Transporter family Phycoerythr_ab PF02972.14 EKX40445.1 - 2.9e-21 75.0 0.1 4.4e-21 74.4 0.1 1.3 1 0 0 1 1 1 1 Phycoerythrin, alpha/beta chain Guanylate_kin PF00625.21 EKX40447.1 - 7.8e-55 185.4 0.0 9.3e-55 185.1 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 EKX40447.1 - 2e-06 28.3 0.0 3.3e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EKX40447.1 - 4.9e-05 23.3 0.0 7.9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 EKX40447.1 - 6.8e-05 23.4 0.1 0.00014 22.4 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EKX40447.1 - 9.7e-05 22.6 0.0 0.00055 20.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EKX40447.1 - 0.0026 18.0 0.8 0.017 15.4 0.3 2.1 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EKX40447.1 - 0.0028 17.7 0.1 0.007 16.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EKX40447.1 - 0.0042 17.6 0.6 0.0096 16.4 0.6 1.9 1 1 0 1 1 1 1 ABC transporter Rad17 PF03215.15 EKX40447.1 - 0.018 15.0 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Septin PF00735.18 EKX40447.1 - 0.041 13.2 0.1 0.071 12.4 0.1 1.4 1 1 0 1 1 1 0 Septin NTPase_1 PF03266.15 EKX40447.1 - 0.05 13.5 0.3 0.089 12.7 0.3 1.6 1 1 0 1 1 1 0 NTPase IstB_IS21 PF01695.17 EKX40447.1 - 0.084 12.6 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein GAT PF03127.14 EKX40447.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 GAT domain cobW PF02492.19 EKX40447.1 - 0.13 11.8 0.6 0.3 10.7 0.2 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 EKX40447.1 - 0.2 11.6 0.3 1.3 8.9 0.3 2.1 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EKX40447.1 - 0.2 12.1 0.0 0.43 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Rhomboid PF01694.22 EKX40448.1 - 3.2e-23 82.4 18.9 5e-23 81.8 18.9 1.2 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 EKX40448.1 - 0.0064 17.0 3.9 0.0064 17.0 3.9 2.1 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) DUF2530 PF10745.9 EKX40448.1 - 1.9 8.7 10.4 4.6 7.5 3.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2530) cobW PF02492.19 EKX40449.1 - 6.5e-44 149.6 0.8 8.6e-44 149.2 0.8 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EKX40449.1 - 5.4e-22 77.5 0.1 2.6e-21 75.4 0.1 2.1 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_18 PF13238.6 EKX40449.1 - 0.0028 18.2 0.6 0.0082 16.7 0.1 2.0 2 0 0 2 2 2 1 AAA domain MobB PF03205.14 EKX40449.1 - 0.0057 16.5 0.0 0.014 15.3 0.0 1.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 EKX40449.1 - 0.0075 16.0 0.1 0.019 14.7 0.1 1.6 1 1 1 2 2 2 1 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 EKX40449.1 - 0.017 15.1 0.1 0.045 13.8 0.0 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 EKX40449.1 - 0.017 15.1 1.3 2.3 8.1 0.2 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 EKX40449.1 - 0.017 15.3 0.1 0.063 13.4 0.1 1.9 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 EKX40449.1 - 0.026 13.5 2.3 3.2 6.7 0.3 2.4 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 EKX40449.1 - 0.037 13.6 0.0 6.7 6.2 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EKX40449.1 - 0.043 14.2 0.5 0.11 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain ATPase_2 PF01637.18 EKX40449.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EKX40449.1 - 0.15 12.4 0.1 0.45 10.8 0.1 1.8 2 1 0 2 2 2 0 AAA domain fn2 PF00040.19 EKX40450.1 - 0.065 13.5 4.7 0.067 13.5 2.8 2.1 2 0 0 2 2 2 0 Fibronectin type II domain EF-hand_8 PF13833.6 EKX40451.1 - 0.0022 17.8 0.2 0.0059 16.4 0.2 1.8 1 0 0 1 1 1 1 EF-hand domain pair DEC-1_N PF04625.13 EKX40451.1 - 0.023 13.8 4.0 0.049 12.7 4.0 1.5 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Parathyroid PF01279.17 EKX40451.1 - 0.069 13.8 0.7 0.6 10.8 0.2 2.9 2 0 0 2 2 2 0 Parathyroid hormone family EF-hand_6 PF13405.6 EKX40451.1 - 0.15 12.1 0.4 8.6 6.6 0.1 2.8 2 0 0 2 2 2 0 EF-hand domain DUF349 PF03993.12 EKX40451.1 - 2.1 8.7 6.5 37 4.7 0.7 4.0 4 0 0 4 4 4 0 Domain of Unknown Function (DUF349) Arm PF00514.23 EKX40452.1 - 1e-18 66.7 0.0 0.00083 19.3 0.0 4.3 4 0 0 4 4 4 4 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EKX40452.1 - 3.4e-09 36.6 0.0 6.5e-05 22.9 0.0 2.5 1 1 2 3 3 3 3 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 EKX40452.1 - 2.6e-07 31.0 0.7 1 9.9 0.0 4.1 2 1 1 3 3 3 3 HEAT-like repeat HEAT PF02985.22 EKX40452.1 - 0.00014 21.8 0.7 45 4.7 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat HEAT_2 PF13646.6 EKX40452.1 - 0.00038 20.8 6.7 0.28 11.6 0.1 2.5 1 1 2 3 3 3 3 HEAT repeats DUF4630 PF15443.6 EKX40452.1 - 0.00094 19.4 9.5 1.1 9.4 0.4 3.9 1 1 3 4 4 4 2 Domain of unknown function (DUF4630) zf-CCHC_6 PF15288.6 EKX40452.1 - 0.018 14.9 1.7 1.4 8.8 0.0 2.8 3 0 0 3 3 3 0 Zinc knuckle ALF PF03752.13 EKX40452.1 - 0.13 12.2 3.4 0.56 10.2 0.1 3.0 3 0 0 3 3 3 0 Short repeats of unknown function DUF1269 PF06897.12 EKX40452.1 - 1.7 9.0 6.5 50 4.2 0.1 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF1269) Arm PF00514.23 EKX40453.1 - 1.3e-13 50.5 0.0 0.048 13.7 0.0 6.7 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat CHAT PF12770.7 EKX40453.1 - 0.0091 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 CHAT domain DUF3361 PF11841.8 EKX40453.1 - 0.02 14.8 0.0 8.9 6.2 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) Atx10homo_assoc PF09759.9 EKX40453.1 - 0.036 14.1 0.1 23 5.1 0.0 4.4 4 1 1 5 5 5 0 Spinocerebellar ataxia type 10 protein domain STN1_2 PF09170.10 EKX40453.1 - 0.042 14.1 0.2 0.12 12.6 0.1 1.7 1 1 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Ephrin_rec_like PF07699.13 EKX40454.1 - 1.3e-11 44.1 20.0 1.4e-07 31.2 6.6 3.6 2 1 1 3 3 3 2 Putative ephrin-receptor like EGF_3 PF12947.7 EKX40454.1 - 1.2e-08 35.0 2.1 1.2e-08 35.0 2.1 3.6 5 0 0 5 5 5 1 EGF domain DUF4215 PF13948.6 EKX40454.1 - 8e-08 32.6 8.3 8e-08 32.6 8.3 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4215) CHB_HEX_C_1 PF13290.6 EKX40454.1 - 2.5e-05 24.2 0.0 0.00036 20.5 0.0 2.4 2 0 0 2 2 2 1 Chitobiase/beta-hexosaminidase C-terminal domain Laminin_G_3 PF13385.6 EKX40454.1 - 0.00028 21.0 0.0 0.0022 18.2 0.0 2.0 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EGF_MSP1_1 PF12946.7 EKX40454.1 - 0.0023 17.9 1.6 0.011 15.8 1.6 2.3 1 0 0 1 1 1 1 MSP1 EGF domain 1 EGF_CA PF07645.15 EKX40454.1 - 0.01 16.0 2.5 0.01 16.0 2.5 4.6 5 1 0 5 5 5 0 Calcium-binding EGF domain cEGF PF12662.7 EKX40454.1 - 0.014 15.3 0.7 0.014 15.3 0.7 3.9 3 0 0 3 3 3 0 Complement Clr-like EGF-like Fn3_assoc PF13287.6 EKX40454.1 - 0.043 14.0 0.0 1.9 8.7 0.0 2.5 2 0 0 2 2 2 0 Fn3 associated Aldolase PF01081.19 EKX40456.1 - 1.3e-31 109.5 0.1 1.7e-31 109.2 0.1 1.1 1 0 0 1 1 1 1 KDPG and KHG aldolase FMN_dh PF01070.18 EKX40456.1 - 0.019 14.0 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase His_biosynth PF00977.21 EKX40456.1 - 0.038 13.4 0.0 0.075 12.5 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein TMP-TENI PF02581.17 EKX40456.1 - 0.14 11.5 0.1 14 4.9 0.0 2.5 3 0 0 3 3 3 0 Thiamine monophosphate synthase RraA-like PF03737.15 EKX40457.1 - 3.5e-29 101.9 0.3 4.8e-29 101.5 0.3 1.1 1 0 0 1 1 1 1 Aldolase/RraA ADH_zinc_N_2 PF13602.6 EKX40458.1 - 4.2e-19 69.9 0.0 1.1e-18 68.6 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EKX40458.1 - 1.7e-13 50.6 0.0 3.1e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EKX40458.1 - 4.9e-09 36.0 0.1 8.9e-09 35.2 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EKX40458.1 - 0.0015 18.4 0.0 0.0043 16.9 0.0 1.8 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EKX40459.1 - 1.2e-21 77.0 0.2 2.1e-21 76.3 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EKX40459.1 - 4.7e-10 40.6 0.2 1.5e-09 39.0 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EKX40459.1 - 6.2e-10 38.9 0.0 1.5e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DapB_N PF01113.20 EKX40459.1 - 0.0013 18.9 0.6 0.0023 18.1 0.6 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Peripla_BP_4 PF13407.6 EKX40459.1 - 0.085 12.4 0.1 0.3 10.6 0.1 2.0 1 1 1 2 2 2 0 Periplasmic binding protein domain ELFV_dehydrog PF00208.21 EKX40459.1 - 0.9 9.2 3.8 1 9.0 1.1 2.2 1 1 1 3 3 3 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DSBA PF01323.20 EKX40460.1 - 1.4e-14 54.3 0.0 1.8e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EKX40460.1 - 0.00017 21.8 0.0 0.00021 21.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 EKX40460.1 - 0.039 14.0 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain UBA_3 PF09288.10 EKX40460.1 - 0.042 13.7 0.0 0.15 11.9 0.0 2.0 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Thioredoxin_5 PF13743.6 EKX40460.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin KdpD PF02702.17 EKX40461.1 - 0.088 12.3 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain Ank_4 PF13637.6 EKX40463.1 - 1.1e-38 131.0 4.6 1.5e-07 31.8 0.0 7.0 5 2 1 7 7 7 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX40463.1 - 2.1e-35 121.1 7.1 3e-09 37.3 0.0 5.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX40463.1 - 1.3e-21 74.4 4.9 0.47 11.2 0.0 10.1 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 EKX40463.1 - 1.7e-20 72.8 6.0 0.057 13.8 0.0 9.2 3 3 7 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.30 EKX40463.1 - 4.5e-11 42.7 11.0 1.6 9.3 0.0 8.9 8 1 0 8 8 8 3 Ankyrin repeat VCPO_N PF17897.1 EKX40463.1 - 0.14 12.0 0.0 8.7 6.1 0.0 2.3 2 0 0 2 2 2 0 Vanadium chloroperoxidase N-terminal domain DUF1147 PF06615.11 EKX40463.1 - 0.19 11.8 8.5 0.58 10.2 0.3 4.9 5 3 1 6 6 6 0 Protein of unknown function (DUF1147) SapB_1 PF05184.15 EKX40463.1 - 1.8 8.7 4.6 72 3.5 0.1 4.6 6 0 0 6 6 6 0 Saposin-like type B, region 1 Ank_4 PF13637.6 EKX40464.1 - 5.7e-08 33.1 0.2 0.0041 17.7 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX40464.1 - 7.4e-08 32.9 0.3 1.1e-07 32.4 0.3 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX40464.1 - 1.5e-05 25.2 1.9 2 9.0 0.1 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EKX40464.1 - 0.00034 20.8 0.2 2.2 9.1 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EKX40464.1 - 0.00053 20.2 0.3 1.2 9.6 0.0 2.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Aminotran_5 PF00266.19 EKX40466.1 - 1.8e-24 86.4 0.0 2.3e-24 86.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EKX40466.1 - 0.00066 19.0 0.0 0.00095 18.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Methyltransf_32 PF13679.6 EKX40467.1 - 4.2e-14 52.8 0.3 3.8e-13 49.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EKX40467.1 - 0.00016 21.2 0.0 0.00033 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EKX40467.1 - 0.0019 18.9 0.2 0.011 16.4 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX40467.1 - 0.025 13.9 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Sigma70_r3 PF04539.16 EKX40467.1 - 0.34 11.0 3.4 8.7 6.5 0.1 2.6 2 0 0 2 2 2 0 Sigma-70 region 3 MORN PF02493.20 EKX40468.1 - 3.8e-29 98.8 54.4 9.7e-07 28.3 3.2 10.2 11 0 0 11 11 11 8 MORN repeat DUF4950 PF16308.5 EKX40468.1 - 0.095 12.7 0.4 0.2 11.6 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4950) Calx-beta PF03160.14 EKX40470.1 - 6e-14 52.0 3.9 0.03 14.5 0.0 7.9 8 0 0 8 8 8 3 Calx-beta domain Ephrin_rec_like PF07699.13 EKX40470.1 - 7.6e-13 48.0 36.5 5.6e-06 26.0 2.4 4.8 3 1 1 4 4 4 4 Putative ephrin-receptor like Laminin_G_3 PF13385.6 EKX40470.1 - 2e-10 41.0 2.6 2e-10 41.0 2.6 3.0 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily LCCL PF03815.19 EKX40470.1 - 0.093 12.9 2.9 0.29 11.3 0.1 3.1 3 0 0 3 3 3 0 LCCL domain Dmrt1 PF12374.8 EKX40470.1 - 1.6 9.2 23.0 78 3.8 0.2 7.9 4 3 3 7 7 7 0 Double-sex mab3 related transcription factor 1 EPTP PF03736.17 EKX40470.1 - 1.9 8.5 7.0 10 6.2 0.5 3.6 3 0 0 3 3 3 0 EPTP domain DUF2207 PF09972.9 EKX40472.1 - 4.5 5.9 4.0 6.6 5.4 4.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SARS_X4 PF08779.10 EKX40473.1 - 0.00073 19.7 5.6 0.0096 16.1 0.5 3.0 2 2 1 4 4 4 2 SARS coronavirus X4 like TNFR_c6 PF00020.18 EKX40473.1 - 0.04 14.3 27.3 3 8.3 3.4 5.4 4 1 0 4 4 4 0 TNFR/NGFR cysteine-rich region GILT PF03227.16 EKX40474.1 - 1.5e-22 79.8 0.6 3.3e-22 78.7 0.6 1.6 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) E7 PF00527.18 EKX40474.1 - 0.073 13.3 2.5 0.3 11.3 2.5 2.2 1 0 0 1 1 1 0 E7 protein, Early protein ATP1G1_PLM_MAT8 PF02038.16 EKX40474.1 - 0.11 12.0 0.1 0.23 10.9 0.1 1.6 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family UBN_AB PF14075.6 EKX40474.1 - 0.16 11.7 10.0 0.45 10.2 10.0 1.7 1 0 0 1 1 1 0 Ubinuclein conserved middle domain DUF489 PF04356.12 EKX40474.1 - 0.32 11.0 4.0 0.21 11.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF489) SpecificRecomb PF10136.9 EKX40474.1 - 1.5 7.0 3.0 2.1 6.5 0.2 2.1 2 1 0 2 2 2 0 Site-specific recombinase Casc1 PF12366.8 EKX40474.1 - 2 7.9 7.9 4 6.9 7.9 1.4 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 HALZ PF02183.18 EKX40477.1 - 0.016 15.4 5.0 0.099 12.9 0.1 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper NYD-SP28_assoc PF14775.6 EKX40477.1 - 8.8 6.5 10.3 17 5.6 0.9 3.2 2 1 1 3 3 3 0 Sperm tail C-terminal domain FYVE PF01363.21 EKX40478.1 - 2.5e-13 50.0 17.9 4.8e-13 49.0 17.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 EKX40478.1 - 1.4e-07 31.9 3.9 4.5e-05 23.9 0.2 3.0 4 0 0 4 4 4 2 PH domain RRXRR PF14239.6 EKX40478.1 - 0.077 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 RRXRR protein UCH PF00443.29 EKX40481.1 - 2.8e-42 145.0 0.3 3.5e-42 144.7 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EKX40481.1 - 3e-23 82.9 4.6 2e-22 80.2 4.6 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PI3Ka PF00613.20 EKX40482.1 - 0.11 11.8 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Rib PF08428.10 EKX40482.1 - 0.19 11.7 0.6 0.67 10.0 0.2 2.0 2 0 0 2 2 2 0 Rib/alpha-like repeat Ank_2 PF12796.7 EKX40483.1 - 4.3e-53 177.9 2.0 3.7e-08 33.9 0.0 7.9 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX40483.1 - 8.6e-40 134.6 10.0 0.00011 22.7 0.0 11.3 6 3 7 13 13 13 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX40483.1 - 1.1e-27 93.0 0.4 0.21 12.3 0.0 13.2 14 0 0 14 14 14 6 Ankyrin repeat Ank_5 PF13857.6 EKX40483.1 - 1.1e-26 92.6 11.0 0.076 13.4 0.0 11.1 5 4 6 11 11 11 9 Ankyrin repeats (many copies) Ank PF00023.30 EKX40483.1 - 3.3e-08 33.6 5.9 96 3.7 0.1 11.9 14 0 0 14 14 14 0 Ankyrin repeat RHH_5 PF07878.11 EKX40483.1 - 0.0039 17.0 11.8 29 4.7 0.1 7.3 9 0 0 9 9 9 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 Lipocalin PF00061.23 EKX40483.1 - 0.0052 17.0 0.0 1.5 9.0 0.0 2.4 2 0 0 2 2 2 2 Lipocalin / cytosolic fatty-acid binding protein family PDZ_6 PF17820.1 EKX40483.1 - 0.054 13.4 0.2 2.5 8.0 0.0 3.9 3 0 0 3 3 3 0 PDZ domain Flg_hook PF02120.16 EKX40484.1 - 0.094 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK RHSP PF07999.11 EKX40486.1 - 0.0063 15.4 0.1 0.013 14.4 0.1 1.5 1 1 0 1 1 1 1 Retrotransposon hot spot protein ATPase PF06745.13 EKX40486.1 - 0.015 14.7 1.0 0.047 13.0 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_16 PF13191.6 EKX40486.1 - 0.054 13.9 0.1 2 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 EKX40486.1 - 0.12 12.7 0.0 0.45 10.9 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Tho2 PF11262.8 EKX40486.1 - 0.35 10.0 4.6 0.57 9.3 4.6 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF4407 PF14362.6 EKX40486.1 - 0.79 9.0 5.1 1.3 8.3 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 EKX40486.1 - 5.6 5.5 9.1 8.7 4.8 9.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Atg14 PF10186.9 EKX40486.1 - 7 5.6 11.4 12 4.9 11.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RHSP PF07999.11 EKX40488.1 - 0.012 14.4 0.1 0.02 13.7 0.1 1.4 1 1 0 1 1 1 0 Retrotransposon hot spot protein ATPase PF06745.13 EKX40488.1 - 0.021 14.2 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 EKX40488.1 - 0.1 13.0 0.0 1.8 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 EKX40488.1 - 0.11 12.9 0.0 0.42 11.0 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Ank_2 PF12796.7 EKX40490.1 - 1.6e-16 60.6 0.0 4.5e-07 30.4 0.0 2.8 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX40490.1 - 4.9e-16 58.9 0.5 3e-05 24.5 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX40490.1 - 1.7e-14 52.4 0.0 0.053 14.1 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EKX40490.1 - 6.4e-07 29.5 0.9 0.031 14.6 0.1 4.1 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX40490.1 - 0.00011 22.5 1.4 10 6.8 0.1 4.4 4 0 0 4 4 4 1 Ankyrin repeat PDZ_6 PF17820.1 EKX40490.1 - 0.0091 15.8 0.3 0.59 10.0 0.1 3.3 3 2 0 3 3 3 1 PDZ domain Voldacs PF03517.13 EKX40491.1 - 4.8e-26 91.5 0.8 7.1e-26 91.0 0.8 1.2 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Vps36_ESCRT-II PF11605.8 EKX40491.1 - 4.6e-08 33.1 0.0 7.5e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 PH_TFIIH PF08567.11 EKX40491.1 - 0.018 15.4 0.0 0.038 14.3 0.0 1.4 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain GRAM PF02893.20 EKX40491.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 GRAM domain Vps54_N PF10475.9 EKX40492.1 - 2.3e-26 92.7 0.4 1.8e-15 57.0 0.2 2.2 2 0 0 2 2 2 2 Vacuolar-sorting protein 54, of GARP complex KRAP_IP3R_bind PF14722.6 EKX40492.1 - 0.035 13.9 0.1 0.12 12.1 0.1 1.9 1 0 0 1 1 1 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain LRR_8 PF13855.6 EKX40495.1 - 5.5e-33 112.5 27.4 3.4e-13 49.1 3.6 3.6 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EKX40495.1 - 1.2e-19 70.1 35.7 1.5e-06 28.4 2.2 4.1 1 1 5 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX40495.1 - 2.3e-05 23.9 3.9 0.035 13.6 0.4 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 EKX40495.1 - 0.0002 21.4 15.2 9.4 7.2 0.1 5.8 5 1 1 6 6 6 2 Leucine Rich Repeat LRR_5 PF13306.6 EKX40495.1 - 0.00043 20.2 2.3 0.0012 18.8 0.8 2.1 1 1 1 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 EKX40495.1 - 0.026 14.6 16.0 4.1 7.7 0.0 5.0 6 0 0 6 6 6 0 Leucine Rich repeat LRR_3 PF07725.12 EKX40495.1 - 0.053 13.4 2.4 2.4 8.2 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich Repeat KH_1 PF00013.29 EKX40496.1 - 5.6e-42 141.4 10.0 3.6e-10 39.5 1.0 5.6 5 0 0 5 5 5 5 KH domain PP2C PF00481.21 EKX40496.1 - 2.7e-22 79.7 0.0 2.7e-22 79.7 0.0 4.1 4 2 1 5 5 5 1 Protein phosphatase 2C KH_2 PF07650.17 EKX40496.1 - 6.4e-11 41.9 13.9 0.0079 16.0 0.1 5.3 4 1 1 5 5 5 4 KH domain MOEP19 PF16005.5 EKX40496.1 - 1.1e-05 25.4 3.4 1.3 9.1 0.1 5.0 5 0 0 5 5 5 2 KH-like RNA-binding domain KH_4 PF13083.6 EKX40496.1 - 1.7e-05 24.6 2.2 1.8 8.5 0.1 4.4 4 0 0 4 4 4 2 KH domain PP2C_2 PF13672.6 EKX40496.1 - 0.00014 21.6 0.2 0.00014 21.6 0.2 3.0 3 0 0 3 3 3 1 Protein phosphatase 2C SH3_12 PF18129.1 EKX40496.1 - 0.17 12.0 0.2 24 5.1 0.0 3.1 3 0 0 3 3 3 0 Xrn1 SH3-like domain KH_5 PF13184.6 EKX40496.1 - 0.34 11.0 2.4 15 5.7 0.1 3.2 3 0 0 3 3 3 0 NusA-like KH domain Peptidase_M8 PF01457.16 EKX40497.1 - 3.6e-66 224.0 2.6 7.9e-51 173.3 2.0 2.1 2 0 0 2 2 2 2 Leishmanolysin Crystall_3 PF08964.10 EKX40498.1 - 0.051 13.8 0.2 0.14 12.3 0.2 1.7 1 0 0 1 1 1 0 Beta/Gamma crystallin Aminotran_5 PF00266.19 EKX40499.1 - 5.6e-88 295.4 0.0 6.8e-88 295.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EKX40499.1 - 6.6e-07 28.9 0.3 9.4e-07 28.4 0.3 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EKX40499.1 - 0.003 16.9 0.3 0.0062 15.9 0.3 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family AP2 PF00847.20 EKX40501.1 - 0.001 19.2 2.4 0.0025 18.0 2.4 1.7 1 0 0 1 1 1 1 AP2 domain Oxidoreduct_C PF16490.5 EKX40501.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Putative oxidoreductase C terminal domain Corona_S2 PF01601.16 EKX40502.1 - 0.75 8.2 2.9 1 7.8 2.9 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein p450 PF00067.22 EKX40503.1 - 1.4e-74 251.5 0.0 1.7e-74 251.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BIR PF00653.21 EKX40504.1 - 5.7e-09 36.5 0.0 1.3e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain EF-hand_1 PF00036.32 EKX40504.1 - 5.8e-09 34.9 3.9 0.0012 18.2 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EKX40504.1 - 2.6e-08 34.2 3.1 0.0032 17.9 0.5 3.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 EKX40504.1 - 6e-07 29.2 1.7 0.039 13.8 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX40504.1 - 2.5e-05 23.8 0.6 0.056 13.4 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 EKX40504.1 - 0.00041 19.7 1.3 0.005 16.3 0.1 2.8 3 0 0 3 3 3 1 EF hand Caleosin PF05042.13 EKX40504.1 - 0.0017 18.3 0.1 0.064 13.2 0.0 2.4 2 0 0 2 2 2 1 Caleosin related protein Peptidase_M3 PF01432.20 EKX40505.1 - 3.9e-102 342.9 0.0 5.9e-102 342.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M32 PF02074.15 EKX40505.1 - 0.043 12.6 0.1 0.084 11.6 0.1 1.4 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase RSN1_7TM PF02714.15 EKX40506.1 - 3.5e-06 26.6 8.3 5.4e-06 25.9 8.3 1.2 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RCC1 PF00415.18 EKX40507.1 - 3.2e-63 210.1 11.1 6.5e-13 49.1 0.1 6.3 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX40507.1 - 4.4e-41 137.9 29.7 4.8e-09 35.8 0.8 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat BCNT PF07572.12 EKX40508.1 - 0.11 12.6 1.6 0.15 12.1 0.1 2.0 2 0 0 2 2 2 0 Bucentaur or craniofacial development Collagen PF01391.18 EKX40509.1 - 6e-23 80.4 95.0 2.9e-09 36.5 28.4 4.0 1 1 1 2 2 2 1 Collagen triple helix repeat (20 copies) SHE3 PF17078.5 EKX40509.1 - 0.083 12.6 0.2 0.11 12.2 0.2 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 NIF PF03031.18 EKX40510.1 - 1.7e-13 50.6 0.0 2.2e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase SSF PF00474.17 EKX40511.1 - 0.00068 18.6 18.7 0.00068 18.6 18.7 2.8 2 1 0 2 2 2 2 Sodium:solute symporter family DUF3681 PF12442.8 EKX40511.1 - 0.096 13.2 10.5 0.15 12.6 0.6 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3681) Pkinase PF00069.25 EKX40512.1 - 7.4e-60 202.5 0.0 8.7e-60 202.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX40512.1 - 4.1e-45 154.1 0.1 5e-45 153.8 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX40512.1 - 3.7e-08 33.0 0.1 8.6e-08 31.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EKX40512.1 - 3.7e-05 22.7 0.0 4.6e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EKX40512.1 - 4.9e-05 22.8 0.2 9.3e-05 21.9 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EKX40512.1 - 0.00019 21.1 0.1 0.00034 20.2 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EKX40512.1 - 0.013 14.4 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EKX40512.1 - 0.056 13.3 0.1 1.5 8.7 0.2 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family AAA PF00004.29 EKX40514.1 - 1.8e-36 125.5 0.0 3e-11 43.9 0.0 3.7 2 1 1 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX40514.1 - 8.3e-11 42.6 11.7 2.4e-06 28.1 3.8 4.0 3 2 0 3 3 2 2 AAA ATPase domain AAA_33 PF13671.6 EKX40514.1 - 1.3e-09 38.3 0.0 4.5e-05 23.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 EKX40514.1 - 1.6e-07 31.4 1.3 0.0077 16.2 0.1 3.4 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) NACHT PF05729.12 EKX40514.1 - 5.7e-07 29.6 3.4 0.00024 21.0 0.2 3.0 2 1 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 EKX40514.1 - 3.1e-06 27.5 5.4 0.00024 21.4 0.1 3.5 4 1 0 4 4 2 1 AAA domain AAA_25 PF13481.6 EKX40514.1 - 6.4e-06 25.9 0.9 0.025 14.2 0.3 2.9 2 1 0 2 2 2 2 AAA domain TsaE PF02367.17 EKX40514.1 - 3.3e-05 23.9 0.3 0.41 10.7 0.1 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EKX40514.1 - 5.2e-05 23.0 0.1 0.089 12.5 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein DUF815 PF05673.13 EKX40514.1 - 0.00021 20.5 0.0 0.067 12.3 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EKX40514.1 - 0.00027 20.7 0.1 0.89 9.3 0.0 3.0 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EKX40514.1 - 0.00066 20.0 0.1 0.94 9.9 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_7 PF12775.7 EKX40514.1 - 0.0018 17.9 0.1 0.41 10.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region PEX-2N PF09263.10 EKX40514.1 - 0.0018 18.5 0.1 0.69 10.3 0.0 2.7 1 1 1 2 2 2 1 Peroxisome biogenesis factor 1, N-terminal AAA_29 PF13555.6 EKX40514.1 - 0.002 17.8 0.0 0.1 12.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.6 EKX40514.1 - 0.0021 18.2 0.9 0.43 10.7 0.0 2.9 3 0 0 3 3 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 EKX40514.1 - 0.0029 16.9 4.0 0.099 11.9 0.3 2.8 3 0 0 3 3 3 1 Zeta toxin Mg_chelatase PF01078.21 EKX40514.1 - 0.012 15.0 0.5 0.83 9.0 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EKX40514.1 - 0.016 14.9 0.3 0.21 11.3 0.0 2.5 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_24 PF13479.6 EKX40514.1 - 0.016 14.9 0.1 1.7 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EKX40514.1 - 0.038 14.6 0.0 17 6.0 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 EKX40514.1 - 0.038 13.7 1.3 0.98 9.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 EKX40514.1 - 0.041 13.1 0.1 0.98 8.5 0.0 2.2 2 0 0 2 2 2 0 TIP49 P-loop domain ABC_tran PF00005.27 EKX40514.1 - 0.082 13.4 3.1 0.63 10.5 0.0 3.0 3 0 0 3 3 3 0 ABC transporter AAA_28 PF13521.6 EKX40514.1 - 0.085 13.1 3.6 8.2 6.6 0.0 3.3 4 0 0 4 4 3 0 AAA domain PhoH PF02562.16 EKX40514.1 - 0.15 11.5 0.5 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein ATPase PF06745.13 EKX40514.1 - 0.36 10.2 2.1 12 5.1 0.0 3.4 4 0 0 4 4 4 0 KaiC MORN PF02493.20 EKX40515.1 - 3e-07 29.9 18.9 0.0021 17.9 2.7 3.8 4 0 0 4 4 4 3 MORN repeat CLP_protease PF00574.23 EKX40517.1 - 7.1e-80 267.2 0.0 8e-80 267.0 0.0 1.0 1 0 0 1 1 1 1 Clp protease DIOX_N PF14226.6 EKX40518.1 - 6.2e-07 30.2 0.0 1.1e-06 29.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Hydrolase_4 PF12146.8 EKX40519.1 - 5.6e-09 35.6 0.0 6.7e-09 35.4 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EKX40519.1 - 6.2e-05 23.7 0.1 6.7e-05 23.6 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.12 EKX40519.1 - 0.00092 18.3 0.0 0.001 18.1 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_3 PF07859.13 EKX40519.1 - 0.0011 18.9 0.0 0.0013 18.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_7 PF12715.7 EKX40519.1 - 0.0033 16.7 0.0 0.0042 16.4 0.0 1.1 1 0 0 1 1 1 1 Abhydrolase family DUF818 PF05677.12 EKX40519.1 - 0.0038 16.2 0.0 0.0042 16.1 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) ELM2 PF01448.24 EKX40520.1 - 0.00012 22.8 0.0 0.00042 21.0 0.0 2.0 1 0 0 1 1 1 1 ELM2 domain DUF3493 PF11998.8 EKX40521.1 - 9.8e-21 73.7 0.3 2e-20 72.7 0.3 1.6 1 0 0 1 1 1 1 Low psii accumulation1 / Rep27 Tail_P2_I PF09684.10 EKX40521.1 - 0.08 12.9 0.1 0.27 11.2 0.2 1.7 2 0 0 2 2 2 0 Phage tail protein (Tail_P2_I) Pyr_redox_2 PF07992.14 EKX40522.1 - 4.5e-27 95.0 0.1 5.7e-27 94.7 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EKX40522.1 - 2e-09 37.9 0.0 2.6e-08 34.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AIF_C PF14721.6 EKX40522.1 - 1.3e-07 32.0 0.3 4.7e-06 27.0 0.1 2.3 1 1 1 2 2 2 1 Apoptosis-inducing factor, mitochondrion-associated, C-term K_oxygenase PF13434.6 EKX40522.1 - 0.0016 17.6 0.1 0.0028 16.9 0.1 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EKX40522.1 - 0.045 13.7 0.8 17 5.3 0.0 3.6 3 1 1 4 4 4 0 FAD-NAD(P)-binding Ntox27 PF15531.6 EKX40522.1 - 0.06 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin 27 ThiF PF00899.21 EKX40522.1 - 0.1 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 ThiF family DAO PF01266.24 EKX40522.1 - 0.11 12.1 0.4 1.6 8.2 0.2 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase Med26 PF08711.11 EKX40523.1 - 0.00034 20.6 0.9 0.00084 19.3 0.9 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF2009 PF09418.10 EKX40524.1 - 7.1e-210 697.8 0.0 8e-210 697.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) Rota_NS53 PF00981.17 EKX40527.1 - 1.1 8.1 9.7 1.6 7.5 9.7 1.2 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) EF-hand_1 PF00036.32 EKX40528.1 - 0.01 15.3 0.1 4 7.2 0.0 2.6 2 0 0 2 2 2 0 EF hand SCPU PF05229.15 EKX40528.1 - 0.056 13.8 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 Spore Coat Protein U domain EF-hand_7 PF13499.6 EKX40528.1 - 0.094 13.2 0.0 8.2 7.0 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 EKX40528.1 - 0.1 12.6 1.4 18 5.6 0.1 3.1 3 0 0 3 3 3 0 EF-hand domain F-box-like PF12937.7 EKX40529.1 - 2.3e-06 27.4 0.1 4.6e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EKX40529.1 - 0.0032 17.3 0.0 0.0058 16.5 0.0 1.4 1 0 0 1 1 1 1 F-box F-box PF00646.33 EKX40529.1 - 0.0099 15.7 0.4 0.024 14.5 0.4 1.6 1 0 0 1 1 1 1 F-box domain Frigida PF07899.11 EKX40529.1 - 0.026 13.8 0.8 0.026 13.8 0.8 1.5 2 0 0 2 2 2 0 Frigida-like protein SBF PF01758.16 EKX40530.1 - 1.1e-30 106.7 13.9 1.1e-30 106.7 13.9 1.8 3 0 0 3 3 3 1 Sodium Bile acid symporter family SBF_like PF13593.6 EKX40530.1 - 6.2e-17 61.9 14.5 1.1e-16 61.1 14.5 1.3 1 1 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) ATG11 PF10377.9 EKX40533.1 - 1.9e-16 60.3 0.0 2e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 11 GST_N_3 PF13417.6 EKX40534.1 - 3.7e-27 94.5 0.1 2.1e-15 56.9 0.0 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EKX40534.1 - 2.2e-10 40.7 0.0 2.5e-05 24.5 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 EKX40534.1 - 0.00057 20.0 0.4 0.094 13.0 0.1 2.7 3 0 0 3 3 3 2 Glutaredoxin GST_N PF02798.20 EKX40534.1 - 0.0046 17.3 0.0 2.7 8.4 0.0 2.7 2 1 0 2 2 2 2 Glutathione S-transferase, N-terminal domain SWIM PF04434.17 EKX40535.1 - 0.0019 17.8 1.5 0.0033 17.1 1.5 1.4 1 0 0 1 1 1 1 SWIM zinc finger DUF3246 PF11596.8 EKX40535.1 - 0.0066 15.9 0.1 0.0066 15.9 0.1 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF3246) PCM1_C PF15717.5 EKX40535.1 - 0.6 8.7 30.2 0.84 8.3 30.2 1.1 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus Ank_4 PF13637.6 EKX40536.1 - 7.1e-27 93.4 0.3 2.3e-08 34.4 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX40536.1 - 2.3e-25 89.0 0.0 7.2e-12 45.7 0.0 2.3 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX40536.1 - 2.6e-23 81.8 0.1 5.9e-08 32.8 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX40536.1 - 1.1e-21 74.5 0.0 0.00037 20.7 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 EKX40536.1 - 2.6e-20 71.9 0.1 0.0023 18.3 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat KID PF02524.14 EKX40537.1 - 0.038 14.0 0.1 0.25 11.6 0.1 2.5 1 0 0 1 1 1 0 KID repeat LUD_dom PF02589.15 EKX40537.1 - 0.12 12.1 0.7 0.27 10.9 0.7 1.6 1 0 0 1 1 1 0 LUD domain DUF1664 PF07889.12 EKX40537.1 - 7.7 6.6 15.6 0.62 10.1 5.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CSD PF00313.22 EKX40538.1 - 6.1e-30 102.9 7.6 5.6e-10 38.9 0.0 9.7 11 0 0 11 11 11 4 'Cold-shock' DNA-binding domain R3H PF01424.22 EKX40538.1 - 1.3e-12 47.5 0.3 3.5e-12 46.1 0.1 1.9 2 0 0 2 2 2 1 R3H domain S1-like PF14444.6 EKX40538.1 - 2.8e-05 24.0 2.9 0.0022 17.9 0.1 4.0 4 0 0 4 4 4 1 S1-like RPN2_C PF18004.1 EKX40538.1 - 0.22 11.4 7.0 2.1 8.2 0.8 2.6 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain RR_TM4-6 PF06459.12 EKX40538.1 - 4 7.2 7.7 13 5.5 0.6 2.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 PAS_9 PF13426.7 EKX40539.1 - 1.4e-06 28.4 0.0 2.7e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 PAS domain zf-C3HC4_2 PF13923.6 EKX40540.1 - 8.6e-09 35.1 10.4 8.6e-09 35.1 10.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX40540.1 - 1.1e-07 31.6 10.8 2.8e-07 30.3 10.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX40540.1 - 1.4e-07 31.4 8.0 1.4e-07 31.4 8.0 2.3 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EKX40540.1 - 1.5e-07 31.1 7.2 4e-07 29.8 7.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX40540.1 - 2.4e-06 27.8 10.7 2.4e-06 27.8 10.7 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 EKX40540.1 - 2.6e-06 27.3 8.5 2.6e-06 27.3 8.5 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EKX40540.1 - 2.6e-05 24.3 10.5 7.2e-05 22.9 10.5 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 EKX40540.1 - 9e-05 22.3 6.0 0.00021 21.1 6.0 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 EKX40540.1 - 0.00013 21.9 2.0 0.00033 20.6 2.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 EKX40540.1 - 0.00036 20.6 7.5 0.00036 20.6 7.5 2.0 2 0 0 2 2 1 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 EKX40540.1 - 0.0007 19.4 9.4 0.0019 18.0 9.4 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EKX40540.1 - 0.0038 16.9 5.1 0.0038 16.9 5.1 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_4 PF14570.6 EKX40540.1 - 0.011 15.6 6.7 0.033 14.0 6.7 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.11 EKX40540.1 - 0.027 14.5 3.6 0.081 13.0 3.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) U-box PF04564.15 EKX40540.1 - 0.036 14.2 0.0 0.079 13.1 0.0 1.5 1 0 0 1 1 1 0 U-box domain zf-Nse PF11789.8 EKX40540.1 - 0.12 12.3 9.3 0.039 13.8 6.2 1.8 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_5 PF17121.5 EKX40540.1 - 0.47 10.4 7.7 0.7 9.8 5.9 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX40540.1 - 0.51 10.7 8.7 0.71 10.2 6.3 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3H2C3 PF17122.5 EKX40540.1 - 2 8.5 6.8 9.3 6.4 6.8 2.1 1 1 0 1 1 1 0 Zinc-finger Anp1 PF03452.14 EKX40541.1 - 0.021 14.2 0.0 0.091 12.2 0.0 1.8 1 1 0 1 1 1 0 Anp1 Radial_spoke PF04712.12 EKX40543.1 - 0.24 10.3 2.3 0.39 9.6 2.3 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein LRR_6 PF13516.6 EKX40544.1 - 1e-27 93.8 15.4 0.00094 19.0 0.0 7.9 8 0 0 8 8 8 7 Leucine Rich repeat LRR_4 PF12799.7 EKX40544.1 - 1.3e-13 50.9 5.4 0.0017 18.7 0.0 5.3 2 2 5 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX40544.1 - 9.8e-11 41.3 9.4 0.002 17.8 0.2 6.3 4 2 1 5 5 5 4 Leucine rich repeat LRR_1 PF00560.33 EKX40544.1 - 1.5e-07 31.0 8.0 12 6.9 0.1 6.9 6 2 0 6 6 6 4 Leucine Rich Repeat RWP-RK PF02042.15 EKX40546.1 - 1.8e-15 56.6 0.1 3.3e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX40546.1 - 0.2 11.4 0.2 0.96 9.3 0.1 2.0 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family RWP-RK PF02042.15 EKX40547.1 - 2.5e-13 49.8 0.0 3.8e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain Na_trans_assoc PF06512.13 EKX40548.1 - 0.00062 20.1 9.6 0.0008 19.8 9.6 1.1 1 0 0 1 1 1 1 Sodium ion transport-associated Nop14 PF04147.12 EKX40548.1 - 0.47 8.6 45.1 0.61 8.2 45.1 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EKX40548.1 - 0.84 7.9 33.2 1.6 6.9 33.2 1.4 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 EKX40548.1 - 0.96 8.2 12.9 1.2 7.8 12.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mpp10 PF04006.12 EKX40548.1 - 1.1 7.6 34.4 1.6 7.0 34.4 1.2 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 EKX40548.1 - 1.1 8.6 45.6 1.4 8.2 45.6 1.1 1 0 0 1 1 1 0 SDA1 RNA_pol_Rpc4 PF05132.14 EKX40548.1 - 1.9 8.9 3.7 2.8 8.3 3.7 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 RRN3 PF05327.11 EKX40548.1 - 2.8 6.4 33.9 4.4 5.7 33.9 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2883 PF11097.8 EKX40549.1 - 0.046 13.8 0.0 0.064 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2883) Peptidase_M24 PF00557.24 EKX40550.1 - 1.7e-36 125.9 0.1 2.2e-36 125.5 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 LOR PF04525.12 EKX40551.1 - 0.00011 21.8 0.0 0.00023 20.8 0.0 1.4 2 0 0 2 2 2 1 LURP-one-related Mito_carr PF00153.27 EKX40552.1 - 1.6e-19 69.6 3.8 3e-06 27.1 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Adenylsucc_synt PF00709.21 EKX40552.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Adenylosuccinate synthetase HAT_KAT11 PF08214.11 EKX40553.1 - 3.1e-14 53.0 0.0 8.1e-14 51.7 0.0 1.7 1 1 0 1 1 1 1 Histone acetylation protein Tudor-knot PF11717.8 EKX40553.1 - 0.0033 17.3 0.0 0.0096 15.8 0.0 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain MBT PF02820.18 EKX40553.1 - 0.04 14.3 0.0 0.16 12.3 0.0 2.1 1 0 0 1 1 1 0 mbt repeat RNA_pol_N PF01194.17 EKX40554.1 - 4.8e-27 94.0 1.7 6.1e-27 93.7 1.7 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 EKX40554.1 - 0.0036 17.5 0.3 0.0048 17.1 0.3 1.2 1 0 0 1 1 1 1 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) DUF3405 PF11885.8 EKX40554.1 - 0.13 10.8 0.0 0.16 10.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) Cullin_binding PF03556.15 EKX40557.1 - 1.6e-31 109.2 2.5 2.7e-31 108.5 2.5 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 EKX40557.1 - 2.7e-09 36.7 0.2 1.9e-08 34.0 0.0 2.3 2 0 0 2 2 2 1 UBA-like domain TAP_C PF03943.13 EKX40557.1 - 0.0049 16.5 0.5 0.028 14.0 0.0 2.3 2 0 0 2 2 2 1 TAP C-terminal domain NAPRTase PF04095.16 EKX40557.1 - 0.14 11.8 0.1 0.21 11.2 0.1 1.2 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family Pyr_redox_2 PF07992.14 EKX40559.1 - 4.4e-15 55.7 3.7 2.8e-11 43.2 1.0 2.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EKX40559.1 - 6.5e-10 39.3 1.2 1.8e-09 37.8 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain FAD_oxidored PF12831.7 EKX40559.1 - 6.8e-06 25.7 1.1 6.8e-06 25.7 1.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EKX40559.1 - 0.00039 19.2 2.4 0.00065 18.5 1.9 1.6 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EKX40559.1 - 0.0013 18.1 0.7 0.0032 16.8 0.7 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 EKX40559.1 - 0.0019 18.4 0.5 0.0019 18.4 0.5 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EKX40559.1 - 0.011 15.0 0.1 0.019 14.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 EKX40559.1 - 0.013 14.6 0.7 0.013 14.6 0.7 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 EKX40559.1 - 0.064 13.8 1.9 0.21 12.2 1.8 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EKX40559.1 - 1.3 8.3 3.8 4 6.6 2.5 2.2 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TPR_1 PF00515.28 EKX40561.1 - 2.2e-33 112.7 13.9 6.4e-07 28.9 0.8 5.9 6 1 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 EKX40561.1 - 1.2e-28 96.9 15.0 5e-07 29.3 1.1 5.6 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_11 PF13414.6 EKX40561.1 - 3e-24 84.4 6.4 2.4e-08 33.5 0.5 5.3 4 1 1 5 5 5 3 TPR repeat TPR_12 PF13424.6 EKX40561.1 - 1.5e-15 57.2 5.8 6.7e-10 39.1 0.3 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX40561.1 - 1.7e-14 54.2 0.0 0.00017 22.2 0.1 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX40561.1 - 1.1e-13 50.8 0.5 0.089 13.7 0.1 5.4 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX40561.1 - 4.4e-13 48.2 2.3 0.04 14.0 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX40561.1 - 9.5e-13 47.3 12.1 0.00081 19.4 0.4 5.2 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 EKX40561.1 - 8.9e-12 44.5 5.6 0.0017 18.6 0.1 5.2 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EKX40561.1 - 1.6e-10 41.3 0.2 0.064 13.8 0.0 4.1 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX40561.1 - 2.6e-08 33.5 0.7 0.031 14.1 0.0 4.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX40561.1 - 8.8e-07 29.0 0.0 0.53 10.5 0.0 3.7 2 2 2 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX40561.1 - 3.9e-06 27.0 5.4 0.002 18.3 0.8 3.4 2 2 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 EKX40561.1 - 0.00011 22.0 2.7 0.0021 17.8 1.6 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat-like domain MIT PF04212.18 EKX40561.1 - 0.00023 21.2 8.2 0.6 10.2 0.1 4.3 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain DUF3856 PF12968.7 EKX40561.1 - 0.0029 17.7 2.0 0.38 10.8 2.2 3.2 2 1 0 2 2 2 1 Domain of Unknown Function (DUF3856) BTAD PF03704.17 EKX40561.1 - 0.0045 17.4 0.8 1 9.8 0.0 2.5 2 0 0 2 2 2 1 Bacterial transcriptional activator domain DUF627 PF04781.12 EKX40561.1 - 0.0088 16.0 0.4 0.0088 16.0 0.4 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF627) TPR_6 PF13174.6 EKX40561.1 - 0.011 16.4 2.6 2.7 8.8 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX40561.1 - 0.018 15.1 4.8 3.1 8.0 0.0 4.2 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat RPN7 PF10602.9 EKX40561.1 - 0.02 14.6 3.0 0.072 12.8 1.2 2.4 2 2 0 2 2 2 0 26S proteasome subunit RPN7 Imm71 PF15602.6 EKX40561.1 - 0.028 14.5 0.1 0.051 13.6 0.1 1.5 1 1 0 1 1 1 0 Immunity protein 71 TPR_4 PF07721.14 EKX40561.1 - 0.041 14.5 0.1 2.1 9.2 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.20 EKX40561.1 - 0.049 13.9 2.3 2.6 8.5 0.1 4.1 4 0 0 4 4 4 0 PPR repeat DUF4919 PF16266.5 EKX40561.1 - 0.057 13.4 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) HemY_N PF07219.13 EKX40561.1 - 1.7 8.8 3.7 22 5.3 1.7 2.8 2 2 1 3 3 3 0 HemY protein N-terminus STI1 PF17830.1 EKX40562.1 - 2.3e-10 40.3 6.8 8.8e-10 38.4 6.8 1.8 1 1 0 1 1 1 1 STI1 domain Phage_stabilise PF11134.8 EKX40563.1 - 0.0044 15.9 0.3 2.6 6.8 0.0 3.3 2 2 0 3 3 3 3 Phage stabilisation protein Melibiase PF02065.18 EKX40564.1 - 2.8e-142 473.7 0.0 4e-142 473.3 0.0 1.2 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 EKX40564.1 - 1.5e-64 218.0 0.0 3.1e-62 210.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 EKX40564.1 - 5.4e-14 52.4 0.1 3.1e-12 46.8 0.0 3.1 3 0 0 3 3 3 1 Glycosyl hydrolase family 36 C-terminal domain Glyco_hydro_31 PF01055.26 EKX40564.1 - 5e-08 32.6 0.0 8e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Melibiase_2 PF16499.5 EKX40564.1 - 0.0004 19.6 0.0 0.00068 18.9 0.0 1.2 1 0 0 1 1 1 1 Alpha galactosidase A Raffinose_syn PF05691.12 EKX40564.1 - 0.21 9.3 0.0 0.31 8.8 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 LYRIC PF15686.5 EKX40565.1 - 1.4 8.4 17.7 2 7.9 17.7 1.2 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family ATP_synt_H PF05493.13 EKX40566.1 - 4.6e-18 65.4 10.0 5.3e-18 65.2 10.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit H DSX_dimer PF08828.10 EKX40566.1 - 0.099 12.3 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Doublesex dimerisation domain FixP_N PF14715.6 EKX40566.1 - 2.3 8.0 5.5 0.54 10.1 1.8 1.9 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP DUF4512 PF14975.6 EKX40567.1 - 0.029 15.1 1.4 0.23 12.3 0.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4512) TauE PF01925.19 EKX40567.1 - 0.12 12.0 8.4 0.015 15.0 4.3 1.5 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE DnaJ PF00226.31 EKX40568.1 - 1.7e-26 92.1 0.1 3.1e-25 88.1 0.6 2.1 2 0 0 2 2 2 1 DnaJ domain Bunya_G2 PF03563.13 EKX40569.1 - 0.028 13.7 0.0 0.035 13.4 0.0 1.1 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 PDZ PF00595.24 EKX40570.1 - 1.9e-05 25.0 0.1 4.3e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX40570.1 - 0.00069 19.4 0.0 0.0055 16.5 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX40570.1 - 0.0038 17.5 0.0 0.0093 16.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain TPR_1 PF00515.28 EKX40573.1 - 1.2e-06 28.1 6.1 0.39 10.6 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX40573.1 - 8.8e-06 25.5 18.3 0.32 11.2 0.2 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX40573.1 - 4.2e-05 23.7 16.5 5.2 7.4 0.1 6.2 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EKX40573.1 - 0.058 13.9 9.9 3.8 8.1 0.0 5.2 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX40573.1 - 0.14 12.5 5.9 3.2 8.2 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 EKX40573.1 - 0.34 10.6 2.7 0.92 9.2 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_14 PF13428.6 EKX40573.1 - 9.2 7.4 14.1 2.9 9.0 0.1 5.9 6 2 2 8 8 8 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX40573.1 - 9.2 6.3 8.1 1.3 9.0 0.1 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat RCR PF12273.8 EKX40575.1 - 0.52 11.0 5.9 0.26 12.0 0.3 2.4 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red UPF0176_N PF17773.1 EKX40577.1 - 1.8e-19 69.9 0.0 3.4e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 EKX40577.1 - 6.5e-09 36.3 0.0 1.1e-08 35.6 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain TPR_8 PF13181.6 EKX40579.1 - 2.6e-07 30.3 0.0 0.013 15.7 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat MSL1_dimer PF16801.5 EKX40579.1 - 0.027 14.2 2.1 2 8.2 0.0 2.6 2 0 0 2 2 2 0 Dimerisation domain of Male-specific-Lethal 1 Toxin_trans PF07952.12 EKX40580.1 - 0.0071 15.5 0.1 0.012 14.8 0.1 1.3 1 0 0 1 1 1 1 Clostridium neurotoxin, Translocation domain TPR_19 PF14559.6 EKX40580.1 - 0.56 10.8 2.5 0.93 10.1 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat RCC1_2 PF13540.6 EKX40581.1 - 6e-18 64.2 47.2 2.8e-06 27.0 5.5 8.5 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Ncstrn_small PF18266.1 EKX40582.1 - 9.8e-21 74.5 0.0 1.9e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Nicastrin small lobe Nicastrin PF05450.15 EKX40582.1 - 9.3e-18 64.5 0.2 3.2e-16 59.5 0.2 2.7 1 1 0 1 1 1 1 Nicastrin Peptidase_M28 PF04389.17 EKX40582.1 - 0.0074 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Ependymin PF00811.18 EKX40583.1 - 0.004 17.4 0.2 0.011 16.0 0.0 1.7 2 0 0 2 2 2 1 Ependymin MTS PF05175.14 EKX40584.1 - 9.2e-15 54.6 0.0 2.2e-12 46.8 0.0 2.0 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_25 PF13649.6 EKX40584.1 - 6.6e-08 33.2 0.0 2.3e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX40584.1 - 1.3e-07 31.6 0.0 2.4e-07 30.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX40584.1 - 7.3e-07 29.9 0.0 1.2e-05 26.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX40584.1 - 2e-05 25.1 0.0 0.00064 20.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EKX40584.1 - 5e-05 22.8 0.0 6.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 EKX40584.1 - 8.8e-05 22.4 0.0 0.0013 18.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_10 PF05971.12 EKX40584.1 - 0.00063 19.2 0.0 0.00081 18.8 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase TehB PF03848.14 EKX40584.1 - 0.0016 17.9 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 EKX40584.1 - 0.0038 17.2 0.0 0.0078 16.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain DUF938 PF06080.12 EKX40584.1 - 0.026 14.3 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_4 PF02390.17 EKX40584.1 - 0.034 13.6 0.0 2.2 7.7 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase CS PF04969.16 EKX40586.1 - 2.3e-07 31.7 0.1 8.9e-07 29.8 0.1 2.1 1 0 0 1 1 1 1 CS domain IGPS PF00218.21 EKX40587.1 - 1.1e-09 37.8 0.1 3.7e-09 36.1 0.1 1.9 1 1 0 1 1 1 1 Indole-3-glycerol phosphate synthase MafB19-deam PF14437.6 EKX40588.1 - 3.7e-29 101.3 0.1 4.3e-29 101.0 0.1 1.1 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 EKX40588.1 - 2.3e-27 94.8 0.1 2.9e-27 94.5 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SNAD4 PF18750.1 EKX40588.1 - 0.00013 22.1 0.0 0.00021 21.4 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 EKX40588.1 - 0.0023 18.1 0.0 0.0034 17.5 0.0 1.2 1 0 0 1 1 1 1 APOBEC3 APOBEC2 PF18772.1 EKX40588.1 - 0.0037 17.3 0.0 0.0051 16.9 0.0 1.2 1 0 0 1 1 1 1 APOBEC2 APOBEC_N PF08210.11 EKX40588.1 - 0.0043 17.0 0.0 0.0045 16.9 0.0 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain NAD2 PF18782.1 EKX40588.1 - 0.0044 17.2 0.0 0.0061 16.7 0.0 1.1 1 0 0 1 1 1 1 Novel AID APOBEC clade 2 Bd3614-deam PF14439.6 EKX40588.1 - 0.0095 16.0 3.1 0.0099 16.0 2.0 1.7 1 1 1 2 2 2 1 Bd3614-like deaminase NAD1 PF18778.1 EKX40588.1 - 0.013 15.6 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 ANAPC10 PF03256.16 EKX40589.1 - 2.8e-25 89.1 0.0 3e-25 88.9 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 EKX40589.1 - 0.022 14.9 0.0 0.025 14.7 0.0 1.2 1 0 0 1 1 1 0 F5/8 type C domain RCC1 PF00415.18 EKX40590.1 - 1e-85 282.2 20.2 3.4e-16 59.6 0.2 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX40590.1 - 5.9e-45 150.2 50.1 3.2e-08 33.1 2.7 8.0 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.6 EKX40590.1 - 2.5e-07 30.8 1.0 0.28 11.5 0.1 5.1 3 2 1 4 4 4 3 Putative heavy-metal chelation ArfA PF03889.13 EKX40591.1 - 0.63 9.6 4.2 1.1 8.8 4.2 1.3 1 0 0 1 1 1 0 Alternative ribosome-rescue factor A EF-hand_7 PF13499.6 EKX40593.1 - 8.5e-06 26.1 3.1 0.0033 17.8 0.3 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX40593.1 - 1.1e-05 24.6 0.6 2.9e-05 23.3 0.6 1.8 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 EKX40593.1 - 0.0011 18.3 0.6 0.0031 16.9 0.3 2.0 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EKX40593.1 - 0.0023 17.8 0.2 0.0057 16.5 0.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX40593.1 - 0.0032 17.3 0.0 0.014 15.3 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain Mobilization_B PF17511.2 EKX40593.1 - 0.018 15.4 12.5 0.051 13.9 2.9 2.7 2 0 0 2 2 2 0 Mobilization protein B Spc7 PF08317.11 EKX40595.1 - 0.035 13.0 11.3 0.053 12.4 11.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 EKX40595.1 - 0.04 14.1 9.9 0.091 12.9 9.9 1.6 1 0 0 1 1 1 0 Tropomyosin like Lebercilin PF15619.6 EKX40595.1 - 0.043 13.5 13.7 0.077 12.6 13.7 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease MAD PF05557.13 EKX40595.1 - 0.096 11.0 12.0 0.13 10.5 12.0 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Fib_alpha PF08702.10 EKX40595.1 - 0.11 12.6 8.1 0.23 11.7 8.1 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1690 PF07956.11 EKX40595.1 - 0.13 12.7 9.8 0.27 11.7 9.8 1.5 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Exonuc_VII_L PF02601.15 EKX40595.1 - 0.13 11.8 5.2 0.17 11.4 5.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit HAP1_N PF04849.13 EKX40595.1 - 0.16 11.2 11.9 0.35 10.0 9.5 2.0 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Fez1 PF06818.15 EKX40595.1 - 0.17 12.3 11.1 0.25 11.8 11.1 1.5 1 1 0 1 1 1 0 Fez1 Atg14 PF10186.9 EKX40595.1 - 0.18 10.9 7.9 0.28 10.2 7.9 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OmpH PF03938.14 EKX40595.1 - 0.24 11.8 9.7 0.57 10.5 9.7 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SF1-HH PF16275.5 EKX40595.1 - 0.31 11.4 5.2 0.61 10.4 1.2 2.7 2 1 1 3 3 3 0 Splicing factor 1 helix-hairpin domain CENP-F_leu_zip PF10473.9 EKX40595.1 - 0.34 10.9 14.2 0.57 10.2 5.8 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_2 PF01920.20 EKX40595.1 - 0.4 10.7 10.7 2.9 7.9 10.2 2.2 1 1 0 1 1 1 0 Prefoldin subunit CC2-LZ PF16516.5 EKX40595.1 - 0.47 10.9 9.8 0.12 12.7 3.9 2.3 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator XhlA PF10779.9 EKX40595.1 - 0.48 10.7 5.9 11 6.4 0.3 2.5 1 1 1 2 2 2 0 Haemolysin XhlA SlyX PF04102.12 EKX40595.1 - 1.7 9.3 8.9 3.4 8.3 1.2 2.5 1 1 1 2 2 2 0 SlyX TMPIT PF07851.13 EKX40595.1 - 2.6 7.2 7.0 4.7 6.3 7.0 1.5 1 0 0 1 1 1 0 TMPIT-like protein FapA PF03961.13 EKX40595.1 - 2.7 6.5 8.1 3.5 6.1 8.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A HR1 PF02185.16 EKX40595.1 - 6.3 7.0 15.1 1.7 8.8 5.3 3.4 2 1 2 4 4 4 0 Hr1 repeat Csm1_N PF18504.1 EKX40595.1 - 6.6 7.1 11.6 6.7 7.1 1.4 2.6 1 1 1 2 2 2 0 Csm1 N-terminal domain CLZ PF16526.5 EKX40595.1 - 8.7 6.8 9.9 3.5 8.0 4.2 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Pkinase_Tyr PF07714.17 EKX40596.1 - 9.6e-65 218.4 0.0 1.1e-64 218.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX40596.1 - 1.7e-32 112.9 0.0 1.9e-32 112.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EKX40596.1 - 0.046 13.0 0.6 0.055 12.8 0.6 1.3 1 1 0 1 1 1 0 Kinase-like Alpha_adaptinC2 PF02883.20 EKX40597.1 - 3.8e-18 65.8 0.0 1.5e-17 63.9 0.0 2.0 2 0 0 2 2 2 1 Adaptin C-terminal domain CHB_HEX_C_1 PF13290.6 EKX40597.1 - 2.1e-07 30.9 0.0 2e-05 24.5 0.0 2.7 2 0 0 2 2 2 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 EKX40597.1 - 2.9e-07 30.5 0.0 2e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 Fn3 associated Abhydrolase_1 PF00561.20 EKX40598.1 - 5.3e-07 29.5 0.0 3.3e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EKX40598.1 - 5.2e-06 26.1 0.0 1.8e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EKX40598.1 - 2.3e-05 25.1 0.0 5e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 EKX40598.1 - 0.018 14.6 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase BAAT_C PF08840.11 EKX40598.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 EKX40598.1 - 0.072 12.3 0.0 0.68 9.1 0.0 2.1 1 1 0 2 2 2 0 Serine aminopeptidase, S33 DLH PF01738.18 EKX40598.1 - 0.098 12.2 0.0 0.24 10.9 0.0 1.5 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF5516 PF17637.2 EKX40598.1 - 2.1 8.2 4.7 1.1 9.1 0.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5516) Ank_4 PF13637.6 EKX40599.1 - 8.4e-17 61.3 0.3 8.5e-10 39.0 0.0 3.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX40599.1 - 1.1e-15 58.0 1.4 5.9e-08 33.2 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX40599.1 - 5.6e-15 55.2 0.7 1.8e-06 28.1 0.1 3.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX40599.1 - 9e-08 31.8 0.5 0.042 14.4 0.0 3.7 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 EKX40599.1 - 3.8e-05 23.9 7.2 0.16 12.5 0.0 4.3 4 2 1 5 5 5 2 Ankyrin repeat PRMT5 PF05185.16 EKX40599.1 - 0.071 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase YchF-GTPase_C PF06071.13 EKX40600.1 - 6.9e-36 122.3 0.3 1.9e-35 120.9 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EKX40600.1 - 1.1e-20 73.8 0.0 2.3e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EKX40600.1 - 1.2e-06 28.2 0.0 7.9e-06 25.5 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EKX40600.1 - 0.0083 16.2 0.1 2.6 8.1 0.0 2.7 2 1 1 3 3 3 2 Dynamin family Roc PF08477.13 EKX40600.1 - 0.038 14.2 0.0 1.7 8.9 0.0 2.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase SecA_PP_bind PF01043.20 EKX40600.1 - 0.077 13.7 0.1 5.8 7.6 0.0 2.4 2 0 0 2 2 2 0 SecA preprotein cross-linking domain ABC_tran PF00005.27 EKX40600.1 - 0.1 13.1 0.0 0.33 11.5 0.0 1.8 1 1 0 1 1 1 0 ABC transporter MeaB PF03308.16 EKX40600.1 - 0.11 11.5 0.6 1.6 7.7 0.0 2.2 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB His_Phos_1 PF00300.22 EKX40601.1 - 1.4e-17 64.1 0.0 3.5e-17 62.7 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PDZ PF00595.24 EKX40601.1 - 9e-10 38.8 0.0 2.3e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX40601.1 - 9.3e-09 35.0 0.0 2.2e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX40601.1 - 1.1e-06 28.8 0.0 2.2e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Myotub-related PF06602.14 EKX40604.1 - 1.1e-124 415.9 0.0 1.4e-124 415.6 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 EKX40604.1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family TolA_bind_tri PF16331.5 EKX40604.1 - 0.016 15.3 1.5 0.032 14.3 1.5 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation DSPc PF00782.20 EKX40604.1 - 0.04 13.7 0.0 0.089 12.6 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain SlyX PF04102.12 EKX40604.1 - 0.063 13.9 0.2 0.15 12.7 0.2 1.6 1 0 0 1 1 1 0 SlyX GIT_CC PF16559.5 EKX40604.1 - 0.07 13.0 0.3 0.2 11.5 0.3 1.8 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor CENP-F_leu_zip PF10473.9 EKX40604.1 - 0.073 13.1 1.7 0.12 12.4 1.7 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 EKX40604.1 - 0.098 13.3 0.1 0.29 11.8 0.1 1.7 1 0 0 1 1 1 0 Initiation control protein YabA JIP_LZII PF16471.5 EKX40604.1 - 0.64 10.2 2.6 1.2 9.4 2.6 1.4 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II LysM PF01476.20 EKX40605.1 - 4.4e-15 55.5 0.1 3.3e-09 36.6 0.0 2.4 2 0 0 2 2 2 2 LysM domain DEAD PF00270.29 EKX40607.1 - 8.4e-41 139.6 0.4 1.2e-40 139.1 0.4 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX40607.1 - 4.4e-22 78.5 0.2 2e-21 76.4 0.1 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX40607.1 - 1.2e-08 35.2 0.0 2.3e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EKX40607.1 - 0.11 11.2 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Pkinase PF00069.25 EKX40608.1 - 2.2e-55 187.8 0.0 1.5e-48 165.4 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EKX40608.1 - 6.7e-42 143.6 0.0 4.6e-39 134.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EKX40608.1 - 2.3e-06 27.2 0.0 3e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like MIR PF02815.19 EKX40608.1 - 0.026 14.4 0.3 0.052 13.4 0.3 1.4 1 0 0 1 1 1 0 MIR domain MPP6 PF10175.9 EKX40608.1 - 0.16 12.5 6.7 0.29 11.6 6.7 1.4 1 0 0 1 1 1 0 M-phase phosphoprotein 6 NOA36 PF06524.12 EKX40608.1 - 3.4 6.9 8.7 7.1 5.9 8.7 1.4 1 0 0 1 1 1 0 NOA36 protein PTH2 PF01981.16 EKX40609.1 - 3e-23 82.3 0.0 3.8e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Fibrinogen_C PF00147.18 EKX40611.1 - 2.7e-06 27.4 0.0 6e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain BCCT PF02028.17 EKX40613.1 - 4.8e-139 463.9 41.7 3.4e-115 385.3 36.1 2.2 1 1 1 2 2 2 2 BCCT, betaine/carnitine/choline family transporter PLAC8 PF04749.17 EKX40613.1 - 0.00043 21.2 0.0 0.00043 21.2 0.0 3.0 4 1 0 4 4 4 1 PLAC8 family LRR_4 PF12799.7 EKX40614.1 - 9.3e-06 25.9 11.1 1.2 9.6 0.0 6.8 6 1 0 7 7 7 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EKX40614.1 - 0.0061 16.5 19.9 18 5.7 0.0 8.2 8 0 0 8 8 8 1 Leucine Rich repeat F-box PF00646.33 EKX40614.1 - 0.025 14.5 3.8 0.27 11.2 0.5 2.9 2 0 0 2 2 2 0 F-box domain LRR_8 PF13855.6 EKX40614.1 - 0.5 10.2 9.2 32 4.4 0.2 5.2 6 0 0 6 6 6 0 Leucine rich repeat F-box-like PF12937.7 EKX40614.1 - 1.1 9.2 4.0 1.3 9.0 0.8 2.6 3 0 0 3 3 3 0 F-box-like Cwf_Cwc_15 PF04889.12 EKX40614.1 - 1.2 8.8 14.5 0.032 14.0 7.5 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 EKX40614.1 - 4.1 6.6 19.0 0.085 12.2 4.3 2.2 2 0 0 2 2 2 0 NOA36 protein DNA_pol_phi PF04931.13 EKX40614.1 - 4.7 5.2 7.7 7 4.6 7.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi FA_hydroxylase PF04116.13 EKX40615.1 - 2.7e-10 40.7 18.8 4e-10 40.2 18.8 1.2 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily DUF1232 PF06803.12 EKX40615.1 - 0.013 15.3 0.3 0.027 14.2 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1232) TraG_N PF07916.11 EKX40615.1 - 3.3 6.5 6.4 5.1 5.8 6.5 1.3 1 1 0 1 1 1 0 TraG-like protein, N-terminal region GFO_IDH_MocA PF01408.22 EKX40616.1 - 7.2e-06 26.8 0.2 1.8e-05 25.6 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Remorin_C PF03763.13 EKX40616.1 - 0.035 14.0 0.1 0.035 14.0 0.1 1.5 2 0 0 2 2 2 0 Remorin, C-terminal region PAS PF00989.25 EKX40619.1 - 2.7e-29 101.5 0.2 5.3e-14 52.2 0.1 3.9 3 0 0 3 3 3 3 PAS fold HATPase_c PF02518.26 EKX40619.1 - 8.3e-18 64.9 0.1 1.7e-17 63.9 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 EKX40619.1 - 1.3e-14 54.3 2.4 6.7e-07 29.5 0.6 3.6 3 0 0 3 3 3 3 PAS domain PAS_4 PF08448.10 EKX40619.1 - 1.8e-12 47.5 0.0 0.00035 20.8 0.0 3.5 3 0 0 3 3 3 2 PAS fold HisKA PF00512.25 EKX40619.1 - 4.9e-12 45.7 0.0 2.2e-11 43.6 0.0 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PHY PF00360.20 EKX40619.1 - 1.8e-10 40.4 0.0 4.1e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Phytochrome region GAF PF01590.26 EKX40619.1 - 4.2e-07 30.7 0.0 5.2e-05 23.9 0.0 2.9 2 0 0 2 2 2 1 GAF domain PAS_8 PF13188.7 EKX40619.1 - 5.1e-05 23.2 0.0 0.14 12.2 0.0 3.1 2 0 0 2 2 2 2 PAS domain PAS_2 PF08446.11 EKX40619.1 - 8.4e-05 23.2 0.0 0.00062 20.4 0.0 2.6 1 0 0 1 1 1 1 PAS fold DnaJ PF00226.31 EKX40620.1 - 3.7e-24 84.6 0.1 8.9e-24 83.4 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain FKBP_C PF00254.28 EKX40621.1 - 3.8e-26 91.2 0.1 9.2e-25 86.8 0.0 2.1 1 1 1 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TAT_signal PF10518.9 EKX40621.1 - 0.00084 19.1 1.2 0.0019 18.0 1.2 1.6 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence WD40 PF00400.32 EKX40622.1 - 5.7e-19 68.1 18.6 3.7e-07 30.7 0.2 9.4 9 1 0 9 9 9 5 WD domain, G-beta repeat EF-hand_7 PF13499.6 EKX40622.1 - 0.018 15.5 0.2 0.047 14.1 0.2 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 EKX40622.1 - 0.11 12.1 0.7 0.28 10.8 0.0 2.1 2 0 0 2 2 2 0 EF hand Hira PF07569.11 EKX40622.1 - 0.15 11.8 0.3 18 5.0 0.0 2.8 2 1 1 3 3 3 0 TUP1-like enhancer of split AAA PF00004.29 EKX40623.1 - 9.5e-19 68.1 0.0 1e-18 68.0 0.0 1.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EKX40623.1 - 2.9e-07 30.1 0.1 0.00061 19.2 0.0 2.1 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EKX40623.1 - 3.6e-06 27.3 0.0 0.00064 20.0 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 EKX40623.1 - 2e-05 24.6 0.2 0.00027 21.0 0.2 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EKX40623.1 - 8e-05 22.8 0.1 0.00012 22.3 0.1 1.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EKX40623.1 - 0.00043 20.7 0.3 0.00088 19.6 0.3 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EKX40623.1 - 0.0011 18.8 0.1 0.0035 17.1 0.1 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EKX40623.1 - 0.0012 19.4 0.0 0.0015 19.1 0.0 1.3 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 EKX40623.1 - 0.002 17.6 0.0 0.0061 16.0 0.0 1.8 1 1 0 1 1 1 1 Chromatin associated protein KTI12 RNA_helicase PF00910.22 EKX40623.1 - 0.003 17.9 0.0 0.0089 16.4 0.0 1.8 1 1 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 EKX40623.1 - 0.0035 17.6 0.0 0.016 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EKX40623.1 - 0.0048 17.3 0.0 0.012 16.1 0.0 1.5 1 1 1 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 EKX40623.1 - 0.0057 16.4 0.0 0.47 10.1 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_30 PF13604.6 EKX40623.1 - 0.0066 16.2 0.1 0.011 15.5 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EKX40623.1 - 0.0094 15.7 0.1 0.01 15.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EKX40623.1 - 0.017 14.6 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 EKX40623.1 - 0.033 13.4 0.2 0.48 9.6 0.1 2.0 1 1 1 2 2 2 0 NB-ARC domain SRP54 PF00448.22 EKX40623.1 - 0.036 13.7 0.1 0.12 12.0 0.0 1.8 1 1 0 2 2 2 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.23 EKX40623.1 - 0.044 13.9 0.1 0.059 13.5 0.1 1.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 EKX40623.1 - 0.05 14.1 0.0 0.06 13.9 0.0 1.3 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 EKX40623.1 - 0.059 13.4 0.0 0.07 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 EKX40623.1 - 0.063 12.6 0.0 0.098 11.9 0.0 1.3 1 1 0 1 1 1 0 6-phosphofructo-2-kinase Viral_helicase1 PF01443.18 EKX40623.1 - 0.083 12.6 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 EKX40623.1 - 0.1 13.0 0.2 0.14 12.6 0.2 1.7 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 EKX40623.1 - 0.12 12.5 0.1 0.21 11.7 0.1 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF3987 PF13148.6 EKX40623.1 - 0.12 11.3 0.0 0.26 10.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) IstB_IS21 PF01695.17 EKX40623.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 EKX40623.1 - 0.19 11.5 0.4 0.27 11.0 0.3 1.4 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 EKX40624.1 - 3e-13 49.8 0.1 3.3e-13 49.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX40624.1 - 7.2e-08 32.0 0.0 8.8e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX40624.1 - 0.0075 15.6 0.1 0.0078 15.6 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EKX40624.1 - 0.012 15.0 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 Kinase-like YukC PF10140.9 EKX40624.1 - 0.18 10.6 0.0 0.19 10.5 0.0 1.0 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC ERM PF00769.19 EKX40625.1 - 0.017 15.0 21.6 0.029 14.2 21.6 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Plasmodium_Vir PF05795.11 EKX40625.1 - 0.32 10.4 1.4 0.43 9.9 1.4 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein 3HCDH_N PF02737.18 EKX40625.1 - 9.1 6.1 8.8 0.62 9.9 1.8 2.3 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain EF-hand_7 PF13499.6 EKX40626.1 - 7.6e-16 58.3 0.5 1.2e-15 57.7 0.5 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX40626.1 - 1.5e-13 49.3 0.2 1.1e-05 24.6 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX40626.1 - 1.1e-11 44.4 0.5 3.9e-06 26.6 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX40626.1 - 9.9e-11 40.7 0.3 6.4e-06 25.7 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EKX40626.1 - 2.2e-08 33.2 0.2 0.0049 16.3 0.0 2.4 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 EKX40626.1 - 0.0023 18.3 0.0 0.0033 17.7 0.0 1.2 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EKX40626.1 - 0.046 13.7 0.1 0.13 12.2 0.0 1.6 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 EKX40626.1 - 0.094 12.6 0.2 11 6.0 0.1 2.3 1 1 1 2 2 2 0 EF hand C2 PF00168.30 EKX40627.1 - 3.7e-27 94.6 0.1 2.9e-15 56.4 0.0 2.5 2 0 0 2 2 2 2 C2 domain LRR_6 PF13516.6 EKX40627.1 - 1.1e-07 31.3 5.7 0.028 14.5 0.1 4.4 5 0 0 5 5 5 2 Leucine Rich repeat CEP76-C2 PF15627.6 EKX40627.1 - 0.006 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 CEP76 C2 domain Telomere_reg-2 PF10193.9 EKX40628.1 - 1.6e-16 60.7 0.0 4.7e-16 59.2 0.0 1.9 1 0 0 1 1 1 1 Telomere length regulation protein CS PF04969.16 EKX40629.1 - 2.6e-09 38.0 1.7 4.1e-09 37.3 1.7 1.2 1 0 0 1 1 1 1 CS domain Siah-Interact_N PF09032.11 EKX40629.1 - 4e-05 23.8 0.0 0.0001 22.5 0.0 1.8 1 0 0 1 1 1 1 Siah interacting protein, N terminal SGS PF05002.15 EKX40629.1 - 0.0034 17.4 0.9 0.0072 16.4 0.9 1.5 1 0 0 1 1 1 1 SGS domain DUF3243 PF11588.8 EKX40629.1 - 0.016 15.5 0.1 0.034 14.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) PRRSV_Env PF02340.15 EKX40629.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 PRRSV putative envelope protein CKS PF01111.19 EKX40630.1 - 7.5e-37 125.4 0.6 9.9e-37 125.1 0.6 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Gln_amidase PF15644.6 EKX40631.1 - 0.34 12.0 4.4 27 5.8 4.3 2.3 1 1 0 1 1 1 0 Papain fold toxin 1, glutamine deamidase Tau95 PF09734.9 EKX40632.1 - 4.6e-20 72.8 0.1 8.6e-20 72.0 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain TFIIF_beta PF02270.15 EKX40632.1 - 0.00032 20.8 0.0 0.00062 19.9 0.0 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain DUF4096 PF13340.6 EKX40632.1 - 0.19 12.0 1.7 17 5.7 0.0 3.7 5 0 0 5 5 5 0 Putative transposase of IS4/5 family (DUF4096) DUF863 PF05904.11 EKX40633.1 - 0.013 14.0 0.6 0.018 13.5 0.6 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) AhpC-TSA_2 PF13911.6 EKX40635.1 - 2.7e-19 69.3 0.0 2.1e-17 63.3 0.0 2.2 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme Redoxin PF08534.10 EKX40635.1 - 0.097 12.4 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Redoxin Radial_spoke PF04712.12 EKX40636.1 - 2.6e-55 188.3 3.7 3e-25 89.2 0.0 3.3 3 1 1 4 4 4 3 Radial spokehead-like protein Bax1-I PF01027.20 EKX40637.1 - 1.2e-31 110.2 35.9 4.6e-30 105.0 35.9 2.0 1 1 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2721 PF11026.8 EKX40637.1 - 0.86 9.5 14.4 0.58 10.0 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Bromodomain PF00439.25 EKX40639.1 - 5.5e-28 96.9 0.0 6.3e-15 55.0 0.0 2.2 2 0 0 2 2 2 2 Bromodomain DUF4658 PF15555.6 EKX40639.1 - 2.1 8.5 5.5 5 7.3 5.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) SelK_SelG PF10961.8 EKX40639.1 - 4.9 7.8 8.9 15 6.3 0.6 2.4 2 0 0 2 2 2 0 Selenoprotein SelK_SelG CDC45 PF02724.14 EKX40639.1 - 7.9 4.6 6.7 11 4.2 6.7 1.1 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.32 EKX40640.1 - 4.1e-24 84.4 16.5 6.4e-06 26.8 0.1 7.5 8 1 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX40640.1 - 8.4e-08 32.4 1.8 1.2 9.4 0.0 6.4 2 2 4 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain NUC205 PF08168.11 EKX40640.1 - 0.03 13.8 0.5 0.1 12.1 0.1 2.0 2 0 0 2 2 2 0 NUC205 domain DUF563 PF04577.14 EKX40641.1 - 5.6e-30 105.0 0.0 1.4e-29 103.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF563) TPR_2 PF07719.17 EKX40641.1 - 1.2e-08 34.4 3.6 0.011 15.7 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX40641.1 - 0.00018 21.2 4.0 0.18 11.7 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX40641.1 - 0.001 19.3 15.3 0.0013 18.9 1.1 4.0 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX40641.1 - 0.0017 19.0 2.0 0.0017 19.0 2.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX40641.1 - 0.016 16.0 0.1 0.016 16.0 0.1 5.1 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EKX40641.1 - 0.028 14.4 0.0 0.31 11.2 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EKX40641.1 - 0.053 13.2 0.8 0.38 10.5 0.0 2.8 3 0 0 3 3 3 0 TPR repeat TPR_17 PF13431.6 EKX40641.1 - 0.12 12.8 0.8 53 4.5 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX40641.1 - 0.62 10.6 0.0 0.62 10.6 0.0 3.5 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX40641.1 - 0.91 9.9 0.0 0.91 9.9 0.0 3.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX40641.1 - 1.1 10.1 5.5 19 6.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX40641.1 - 8.4 6.4 10.9 2.8 8.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat WW PF00397.26 EKX40643.1 - 2.7e-09 36.9 0.4 5.2e-09 36.0 0.4 1.5 1 0 0 1 1 1 1 WW domain Arm PF00514.23 EKX40643.1 - 1.2e-08 34.7 1.3 4.3e-05 23.4 0.0 4.4 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EKX40643.1 - 0.00082 19.8 0.1 0.46 11.1 0.0 3.0 2 0 0 2 2 2 2 HEAT-like repeat DUF2385 PF09539.10 EKX40643.1 - 0.16 12.5 2.3 0.53 10.8 2.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2385) Herpes_DNAp_acc PF04929.12 EKX40643.1 - 1.9 7.4 11.3 0.32 9.9 0.5 2.2 2 0 0 2 2 2 0 Herpes DNA replication accessory factor Activator-TraM PF11657.8 EKX40643.1 - 5.4 6.9 8.9 1.5 8.6 5.3 1.9 2 0 0 2 2 2 0 Transcriptional activator TraM Guanylate_cyc PF00211.20 EKX40644.1 - 1.8e-29 102.6 0.1 2.2e-29 102.4 0.1 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain RBFA PF02033.18 EKX40645.1 - 1.2e-11 44.9 0.0 2.8e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Ribosome-binding factor A DUF2358 PF10184.9 EKX40646.1 - 1e-17 64.4 0.0 8.2e-16 58.3 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2358) SOUL PF04832.12 EKX40646.1 - 7.6e-05 23.0 0.0 0.0003 21.0 0.0 2.0 2 1 0 2 2 2 1 SOUL heme-binding protein SnoaL_2 PF12680.7 EKX40646.1 - 0.0001 22.9 0.0 0.0002 22.0 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain STIL_N PF15253.6 EKX40647.1 - 1.5e-26 93.3 0.0 2.1e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 SCL-interrupting locus protein N-terminus PDZ_6 PF17820.1 EKX40648.1 - 1.7e-12 47.0 0.0 7.2e-12 45.0 0.0 2.1 2 0 0 2 2 2 1 PDZ domain C2 PF00168.30 EKX40648.1 - 7.8e-12 45.4 0.9 0.00011 22.4 0.1 6.0 3 2 0 3 3 3 2 C2 domain WW PF00397.26 EKX40648.1 - 3.8e-08 33.3 0.3 7.9e-08 32.3 0.3 1.6 1 0 0 1 1 1 1 WW domain PDZ PF00595.24 EKX40648.1 - 0.00017 21.9 0.0 0.00036 20.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain NT-C2 PF10358.9 EKX40648.1 - 0.035 13.8 0.0 4.9 6.9 0.0 2.8 2 0 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins Tricorn_PDZ PF14685.6 EKX40648.1 - 0.042 13.8 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Tricorn protease PDZ domain ABC_membrane PF00664.23 EKX40649.1 - 1.4e-80 270.8 24.4 2.8e-43 148.5 15.8 3.0 2 1 1 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 EKX40649.1 - 1.7e-71 239.1 0.0 2.5e-34 118.7 0.0 3.0 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 EKX40649.1 - 2.5e-15 56.5 0.5 0.00027 20.4 0.0 4.3 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 EKX40649.1 - 3.7e-13 49.1 0.1 0.00014 20.8 0.0 4.1 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 EKX40649.1 - 2.9e-11 43.8 0.1 0.00069 19.9 0.0 3.9 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EKX40649.1 - 1.1e-08 35.2 0.0 0.0035 17.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EKX40649.1 - 1.9e-08 33.9 0.2 0.0044 16.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EKX40649.1 - 3.2e-07 30.9 7.6 0.0036 17.7 0.2 3.8 2 2 1 3 3 3 2 AAA ATPase domain AAA_15 PF13175.6 EKX40649.1 - 6.9e-07 29.3 0.0 0.004 16.9 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 EKX40649.1 - 8.5e-06 25.8 0.0 0.11 12.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EKX40649.1 - 2.1e-05 24.2 0.5 0.33 10.5 0.0 3.3 3 0 0 3 3 3 2 AAA domain G-alpha PF00503.20 EKX40649.1 - 5.4e-05 22.5 0.0 0.26 10.4 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_5 PF07728.14 EKX40649.1 - 8.6e-05 22.6 0.1 0.87 9.6 0.0 3.8 5 0 0 5 5 3 2 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 EKX40649.1 - 9.5e-05 23.0 0.3 0.48 10.9 0.0 3.0 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 EKX40649.1 - 0.00011 21.6 0.0 0.34 10.1 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin DUF815 PF05673.13 EKX40649.1 - 0.00065 18.9 0.0 0.65 9.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) NACHT PF05729.12 EKX40649.1 - 0.0018 18.2 0.4 0.72 9.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.22 EKX40649.1 - 0.0021 17.3 0.1 0.12 11.6 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.29 EKX40649.1 - 0.0022 18.4 0.2 4 7.9 0.1 4.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EKX40649.1 - 0.0024 17.4 0.1 2.5 7.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 EKX40649.1 - 0.003 17.3 0.1 3.8 7.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EKX40649.1 - 0.0033 17.2 13.5 0.85 9.3 9.0 4.0 4 1 0 4 4 3 1 AAA domain PRK PF00485.18 EKX40649.1 - 0.0082 15.9 0.0 4.5 7.0 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family DLIC PF05783.11 EKX40649.1 - 0.013 14.3 0.1 4.3 6.1 0.0 2.3 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) MMR_HSR1 PF01926.23 EKX40649.1 - 0.014 15.4 0.0 5.5 7.1 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 EKX40649.1 - 0.016 15.6 0.0 3.8 7.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.18 EKX40649.1 - 0.016 14.9 0.0 3.6 7.3 0.0 3.2 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 EKX40649.1 - 0.019 14.9 0.0 1.2 9.1 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain APS_kinase PF01583.20 EKX40649.1 - 0.024 14.5 0.1 9.5 6.1 0.0 2.8 2 0 0 2 2 2 0 Adenylylsulphate kinase SbcCD_C PF13558.6 EKX40649.1 - 0.024 14.9 4.7 5.5 7.3 0.6 4.1 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATPase PF06745.13 EKX40649.1 - 0.029 13.7 0.2 7.2 5.9 0.0 2.4 2 0 0 2 2 2 0 KaiC Roc PF08477.13 EKX40649.1 - 0.031 14.5 0.0 8.4 6.6 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 EKX40649.1 - 0.039 13.4 0.0 42 3.5 0.0 3.6 4 0 0 4 4 4 0 Bacterial TniB protein AAA_33 PF13671.6 EKX40649.1 - 0.054 13.7 0.0 18 5.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EKX40649.1 - 0.066 13.3 0.2 8.5 6.4 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain TsaE PF02367.17 EKX40649.1 - 0.11 12.5 0.0 9.1 6.3 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 EKX40649.1 - 0.11 12.2 0.1 4.9 6.9 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.25 EKX40649.1 - 0.25 11.0 1.1 24 4.5 0.0 2.7 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain 5_nucleotid PF05761.14 EKX40650.1 - 1.8e-140 468.9 4.9 2e-140 468.7 4.9 1.0 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.6 EKX40650.1 - 0.0036 17.4 1.5 2.9 8.0 0.0 3.1 4 0 0 4 4 4 2 Haloacid dehalogenase-like hydrolase CRAL_TRIO PF00650.20 EKX40651.1 - 4.7e-15 55.7 0.0 7.3e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 EKX40651.1 - 0.039 14.4 0.0 3.3 8.2 0.1 2.3 1 1 1 2 2 2 0 Golgi-dynamics membrane-trafficking Guanylate_cyc PF00211.20 EKX40652.1 - 8.5e-21 74.4 0.1 9.5e-21 74.2 0.1 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain TPH PF13868.6 EKX40654.1 - 4.1e-19 68.3 145.8 4.1e-19 68.3 145.8 2.1 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Acetyltransf_1 PF00583.25 EKX40655.1 - 5.1e-09 36.4 0.0 9.4e-09 35.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EKX40655.1 - 3.1e-05 23.9 0.0 7.1e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EKX40655.1 - 7.6e-05 23.1 0.1 0.00014 22.2 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EKX40655.1 - 0.074 13.1 0.1 1.9 8.6 0.1 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Xpo1 PF08389.12 EKX40656.1 - 8.2e-14 51.9 2.2 1.8e-13 50.8 0.8 2.5 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 EKX40656.1 - 0.0031 17.4 0.1 0.055 13.4 0.0 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain Condensin2nSMC PF12422.8 EKX40656.1 - 3.8 7.7 5.6 5.5 7.2 0.0 3.8 5 0 0 5 5 5 0 Condensin II non structural maintenance of chromosomes subunit UCH PF00443.29 EKX40658.1 - 2.2e-19 69.9 0.0 1.3e-10 41.2 0.0 3.0 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EKX40658.1 - 5.3e-08 32.5 0.4 0.00071 19.3 0.0 3.9 4 0 0 4 4 4 2 Ubiquitin family UCH_1 PF13423.6 EKX40658.1 - 4.3e-05 23.3 0.1 0.0062 16.2 0.0 2.4 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UN_NPL4 PF11543.8 EKX40658.1 - 0.00068 20.1 0.0 0.31 11.5 0.0 3.5 3 0 0 3 3 3 1 Nuclear pore localisation protein NPL4 Ubiquitin_2 PF14560.6 EKX40658.1 - 0.0016 18.9 0.1 8.7 6.9 0.0 3.6 3 0 0 3 3 3 1 Ubiquitin-like domain NmrA PF05368.13 EKX40659.1 - 6.3e-23 81.6 0.4 5.7e-22 78.4 0.4 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EKX40659.1 - 3.3e-14 53.2 0.0 3.6e-12 46.5 0.0 2.2 2 0 0 2 2 2 2 NAD(P)H-binding Epimerase PF01370.21 EKX40659.1 - 8.1e-05 22.2 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EKX40659.1 - 0.0012 17.9 0.5 0.012 14.6 0.5 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EKX40659.1 - 0.026 14.4 0.0 0.099 12.6 0.0 2.0 2 1 0 2 2 2 0 KR domain WBS_methylT PF12589.8 EKX40660.1 - 1.5e-14 54.5 10.1 2.4e-14 53.8 10.1 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 EKX40660.1 - 1.1e-12 48.4 0.0 2.6e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX40660.1 - 7.4e-11 42.6 0.0 1.5e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX40660.1 - 3.7e-05 23.6 0.0 5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX40660.1 - 0.00016 21.5 0.0 0.00022 21.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX40660.1 - 0.00019 22.1 0.2 0.00055 20.6 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain N6_N4_Mtase PF01555.18 EKX40660.1 - 0.0012 18.7 0.5 0.0058 16.4 0.0 2.2 2 1 0 2 2 2 1 DNA methylase CMAS PF02353.20 EKX40660.1 - 0.0021 17.4 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 EKX40660.1 - 0.0081 15.9 0.1 0.018 14.8 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 EKX40660.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MetW PF07021.12 EKX40660.1 - 0.085 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW AdoMet_MTase PF07757.13 EKX40660.1 - 0.086 13.2 0.0 0.22 11.9 0.0 1.7 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase MTS PF05175.14 EKX40660.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 EKX40660.1 - 0.15 11.4 0.2 0.6 9.4 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) EF-hand_5 PF13202.6 EKX40662.1 - 0.0018 17.7 0.1 0.004 16.6 0.1 1.5 1 0 0 1 1 1 1 EF hand TcdB_toxin_midN PF12256.8 EKX40662.1 - 0.0033 16.8 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Insecticide toxin TcdB middle/N-terminal region EF-hand_1 PF00036.32 EKX40662.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 EF hand SUR7 PF06687.12 EKX40662.1 - 0.026 14.2 0.0 0.031 13.9 0.0 1.1 1 0 0 1 1 1 0 SUR7/PalI family Nuc_N PF14448.6 EKX40662.1 - 0.079 12.8 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Nuclease N terminal EF-hand_6 PF13405.6 EKX40662.1 - 0.081 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain Dockerin_1 PF00404.18 EKX40662.1 - 0.12 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Dockerin type I domain Zn_clus PF00172.18 EKX40664.1 - 0.00021 21.4 10.1 0.00072 19.6 10.1 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CelTOS PF18659.1 EKX40664.1 - 0.16 12.4 0.2 0.92 10.0 0.0 2.2 3 0 0 3 3 3 0 Cell-traversal protein for ookinetes and sporozoites STAT_alpha PF01017.20 EKX40665.1 - 0.2 11.5 7.9 0.21 11.5 7.9 1.0 1 0 0 1 1 1 0 STAT protein, all-alpha domain Na_Ca_ex PF01699.24 EKX40666.1 - 6e-45 152.9 44.9 3.2e-24 85.6 17.4 2.6 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Mit_KHE1 PF10173.9 EKX40667.1 - 0.0023 18.0 0.3 0.0048 17.0 0.3 1.5 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related LMBR1 PF04791.16 EKX40667.1 - 0.027 13.4 1.8 0.033 13.1 1.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein ArAE_2 PF10334.9 EKX40667.1 - 0.055 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 Lectin_N PF03954.14 EKX40667.1 - 0.069 12.9 4.8 0.033 13.9 2.0 1.9 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain BLOC1_2 PF10046.9 EKX40667.1 - 2.4 8.5 9.0 0.85 10.0 2.0 2.8 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 EKX40667.1 - 3.1 8.0 6.8 2.2 8.5 4.1 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Peptidase_M28 PF04389.17 EKX40670.1 - 1.1e-22 80.7 0.0 1.5e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EKX40670.1 - 2.4e-08 33.9 0.1 5e-08 32.9 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 PA PF02225.22 EKX40670.1 - 3.6e-07 30.1 0.0 1.2e-06 28.4 0.0 1.9 1 0 0 1 1 1 1 PA domain Tricorn_C1 PF14684.6 EKX40671.1 - 0.021 14.9 0.4 0.041 14.0 0.4 1.5 1 0 0 1 1 1 0 Tricorn protease C1 domain DUF3824 PF12868.7 EKX40671.1 - 0.077 13.7 0.3 0.13 12.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) LysM PF01476.20 EKX40672.1 - 0.00019 21.4 0.2 0.018 15.1 0.0 2.3 2 0 0 2 2 2 2 LysM domain RCC1_2 PF13540.6 EKX40673.1 - 3.9e-33 112.5 46.8 7.1e-12 44.8 1.6 5.9 5 1 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EKX40673.1 - 1.8 9.3 0.0 1.8 9.3 0.0 7.4 6 3 2 8 8 8 0 Regulator of chromosome condensation (RCC1) repeat DUF4215 PF13948.6 EKX40674.1 - 6.4e-25 87.3 40.2 1.9e-08 34.6 3.6 4.1 4 1 0 4 4 4 3 Domain of unknown function (DUF4215) RCC1_2 PF13540.6 EKX40675.1 - 3e-48 160.7 52.7 2.8e-10 39.7 1.4 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EKX40675.1 - 1.5e-06 28.7 38.2 1.1 10.0 0.1 10.3 10 2 1 11 11 11 5 Regulator of chromosome condensation (RCC1) repeat Kelch_5 PF13854.6 EKX40675.1 - 0.0014 18.6 6.9 2 8.5 0.0 4.6 5 0 0 5 5 5 3 Kelch motif TPR_17 PF13431.6 EKX40676.1 - 1e-15 56.9 0.4 0.0071 16.7 0.0 7.7 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX40676.1 - 3.4e-15 55.4 0.0 0.00062 20.4 0.0 7.7 6 3 2 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX40676.1 - 8.6e-15 54.1 0.3 0.0058 16.3 0.1 6.9 7 0 0 7 7 7 3 TPR repeat TPR_8 PF13181.6 EKX40676.1 - 1e-12 47.2 0.0 0.016 15.4 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 EKX40676.1 - 1.3e-11 44.8 1.0 0.00081 19.9 0.2 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX40676.1 - 1.8e-10 40.1 0.8 0.05 13.7 0.0 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX40676.1 - 8.4e-08 31.7 1.1 0.62 10.0 0.0 5.2 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX40676.1 - 6.1e-07 30.0 1.2 0.042 14.5 0.0 5.2 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX40676.1 - 6.3e-06 25.9 0.0 0.19 11.8 0.0 3.7 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX40676.1 - 0.00097 19.4 1.6 3 8.2 0.1 4.9 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX40676.1 - 0.0018 18.4 0.5 0.037 14.2 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX40676.1 - 0.11 12.5 0.1 0.41 10.7 0.1 1.9 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Tcf25 PF04910.14 EKX40676.1 - 0.11 11.5 1.3 9.7 5.1 0.1 2.9 4 0 0 4 4 4 0 Transcriptional repressor TCF25 TPR_10 PF13374.6 EKX40676.1 - 2.6 8.0 5.8 6 6.9 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EKX40677.1 - 1.2e-38 131.9 0.1 1.7e-38 131.4 0.1 1.2 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_I_2 PF17014.5 EKX40677.1 - 0.0071 16.5 0.1 0.012 15.8 0.1 1.3 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein RGS-like PF09128.11 EKX40677.1 - 0.024 14.4 0.0 0.052 13.2 0.0 1.6 1 1 0 1 1 1 0 Regulator of G protein signalling-like domain Brr6_like_C_C PF10104.9 EKX40677.1 - 0.41 10.4 1.5 1.8 8.3 0.4 2.1 1 1 1 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain Pkinase PF00069.25 EKX40678.1 - 0.037 13.4 0.0 0.041 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.25 EKX40679.1 - 6.6e-78 261.7 0.0 7.5e-78 261.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX40679.1 - 8e-44 149.9 0.0 9e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX40679.1 - 1.4e-06 27.4 0.0 2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EKX40679.1 - 2.6e-06 27.0 0.1 1.6e-05 24.4 0.0 1.9 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 EKX40679.1 - 0.0015 18.2 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EKX40679.1 - 0.0032 17.1 0.1 0.012 15.2 0.0 1.7 1 1 0 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 EKX40679.1 - 0.0044 16.0 0.0 0.017 14.1 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EKX40679.1 - 0.0061 16.5 0.0 0.0089 16.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX40679.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EKX40679.1 - 0.019 14.5 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.11 EKX40679.1 - 0.095 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Cyclin_N PF00134.23 EKX40680.1 - 3.8e-12 46.1 0.2 6.5e-12 45.3 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EKX40680.1 - 1.6e-11 44.3 0.3 2e-10 40.8 0.1 2.2 2 0 0 2 2 2 1 Cyclin, C-terminal domain NAF PF03822.14 EKX40680.1 - 0.036 14.2 0.0 0.11 12.7 0.0 1.8 2 0 0 2 2 2 0 NAF domain RabGAP-TBC PF00566.18 EKX40685.1 - 5.6e-30 104.6 2.5 1.8e-28 99.7 0.5 2.2 1 1 1 2 2 2 2 Rab-GTPase-TBC domain Rhodanese PF00581.20 EKX40685.1 - 3.1e-09 37.3 0.0 6.3e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Myosin_TH1 PF06017.13 EKX40685.1 - 0.066 12.9 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding 60KD_IMP PF02096.20 EKX40686.1 - 0.00016 21.6 0.5 0.00072 19.5 0.5 1.9 1 1 0 1 1 1 1 60Kd inner membrane protein TENA_THI-4 PF03070.16 EKX40687.1 - 3.3e-35 121.8 0.5 3.7e-35 121.7 0.5 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Arf PF00025.21 EKX40688.1 - 2.8e-63 212.5 0.1 3.4e-63 212.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EKX40688.1 - 6.4e-15 55.4 0.0 8.6e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EKX40688.1 - 6.4e-14 51.9 0.0 7.1e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EKX40688.1 - 4.9e-13 48.9 0.0 6.2e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EKX40688.1 - 9e-07 29.0 0.1 1.6e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EKX40688.1 - 9.1e-07 28.4 0.3 6.1e-05 22.3 0.0 2.3 1 1 1 2 2 2 1 G-protein alpha subunit Gtr1_RagA PF04670.12 EKX40688.1 - 1.5e-06 27.8 0.0 1.9e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_33 PF13671.6 EKX40688.1 - 0.035 14.3 0.0 0.076 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EKX40688.1 - 0.054 13.8 0.2 0.17 12.1 0.2 1.6 1 1 0 1 1 1 0 AAA domain NAD_binding_5 PF07994.12 EKX40688.1 - 0.097 12.0 0.1 0.31 10.4 0.0 1.7 2 0 0 2 2 2 0 Myo-inositol-1-phosphate synthase AAA_24 PF13479.6 EKX40688.1 - 0.13 12.0 0.1 0.21 11.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain VPS13_C PF16909.5 EKX40689.1 - 4e-61 205.9 1.1 8.6e-61 204.8 0.8 1.6 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal vATP-synt_E PF01991.18 EKX40689.1 - 0.016 14.6 2.0 0.031 13.7 2.0 1.4 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit GA PF01468.17 EKX40689.1 - 0.082 13.2 0.9 0.18 12.1 0.9 1.6 1 0 0 1 1 1 0 GA module Carla_C4 PF01623.17 EKX40689.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein SieB PF14163.6 EKX40691.1 - 0.33 10.4 1.3 11 5.6 0.1 2.2 2 0 0 2 2 2 0 Super-infection exclusion protein B Yae1_N PF09811.9 EKX40692.1 - 0.0039 16.9 31.5 0.17 11.6 6.9 6.5 4 2 1 5 5 5 3 Essential protein Yae1, N terminal DUF5549 PF17703.1 EKX40692.1 - 0.069 12.8 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5549) MspA PF09203.11 EKX40692.1 - 0.28 11.0 17.5 0.19 11.6 4.0 2.9 1 1 1 2 2 2 0 MspA TSNAXIP1_N PF15739.5 EKX40693.1 - 6.8e-05 23.2 10.3 6.8e-05 23.2 10.3 3.2 1 1 2 3 3 3 1 Translin-associated factor X-interacting N-terminus DUF1192 PF06698.11 EKX40693.1 - 2.9 8.0 8.3 26 4.9 4.4 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Spc24 PF08286.11 EKX40693.1 - 7.8 6.8 12.0 2.4 8.4 7.8 2.3 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 CBM_48 PF02922.18 EKX40694.1 - 0.18 12.2 0.1 4.8 7.6 0.0 2.7 2 1 1 3 3 3 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) SH3_15 PF18346.1 EKX40696.1 - 0.15 12.4 0.2 0.15 12.4 0.2 1.6 2 0 0 2 2 2 0 Mind bomb SH3 repeat domain Macoilin PF09726.9 EKX40697.1 - 4.3 5.8 13.7 4.7 5.6 13.7 1.1 1 0 0 1 1 1 0 Macoilin family Lung_7-TM_R PF06814.13 EKX40699.1 - 3.1e-24 85.7 4.7 1.8e-16 60.3 1.4 2.1 2 0 0 2 2 2 2 Lung seven transmembrane receptor PRK PF00485.18 EKX40700.1 - 1.1e-72 244.0 0.0 1.6e-72 243.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family TsaE PF02367.17 EKX40700.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EKX40700.1 - 0.15 11.3 0.1 0.32 10.2 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 EKX40700.1 - 0.17 12.4 0.3 0.33 11.4 0.4 1.5 1 1 0 1 1 1 0 AAA domain JAKMIP_CC3 PF16034.5 EKX40702.1 - 0.00078 19.5 3.4 0.00078 19.5 3.4 2.1 2 0 0 2 2 2 1 JAKMIP CC3 domain Lebercilin PF15619.6 EKX40702.1 - 0.0032 17.1 1.1 0.0032 17.1 1.1 2.2 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease ZapB PF06005.12 EKX40702.1 - 0.0035 17.8 8.1 0.014 15.8 3.5 3.3 3 0 0 3 3 3 1 Cell division protein ZapB TMF_TATA_bd PF12325.8 EKX40702.1 - 0.0035 17.5 2.9 0.0035 17.5 2.9 3.0 2 2 2 4 4 4 1 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 EKX40702.1 - 0.029 14.5 1.5 0.029 14.5 1.5 2.7 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding TACC_C PF05010.14 EKX40702.1 - 0.029 14.1 0.8 0.029 14.1 0.8 2.6 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal bZIP_1 PF00170.21 EKX40702.1 - 0.049 13.7 6.3 0.2 11.8 0.5 3.9 4 0 0 4 4 4 0 bZIP transcription factor DUF4407 PF14362.6 EKX40702.1 - 0.11 11.8 3.6 0.067 12.5 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) AKNA PF12443.8 EKX40702.1 - 0.12 13.1 4.2 2.3 8.9 0.1 3.7 3 0 0 3 3 3 0 AT-hook-containing transcription factor Ca_chan_IQ PF08763.11 EKX40702.1 - 0.17 12.1 1.3 0.32 11.2 0.2 2.0 2 0 0 2 2 1 0 Voltage gated calcium channel IQ domain CENP-Q PF13094.6 EKX40702.1 - 0.24 11.6 7.2 0.028 14.6 2.5 1.9 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit T3SSipB PF16535.5 EKX40702.1 - 0.31 11.5 3.6 4.1 7.9 3.6 2.6 1 1 0 1 1 1 0 Type III cell invasion protein SipB Seryl_tRNA_N PF02403.22 EKX40702.1 - 0.38 11.0 12.9 13 6.1 0.2 3.6 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 EKX40702.1 - 0.46 11.0 12.3 0.064 13.8 5.0 2.8 2 1 1 3 3 3 0 Apg6 coiled-coil region YabA PF06156.13 EKX40702.1 - 0.47 11.1 7.6 0.38 11.4 1.9 3.1 2 1 1 3 3 3 0 Initiation control protein YabA LprI PF07007.12 EKX40702.1 - 0.5 11.0 2.7 0.41 11.3 0.6 2.0 2 0 0 2 2 1 0 Lysozyme inhibitor LprI Sec34 PF04136.15 EKX40702.1 - 0.58 10.0 6.6 0.18 11.7 2.4 2.2 2 1 0 2 2 2 0 Sec34-like family FlaC_arch PF05377.11 EKX40702.1 - 0.69 10.4 4.3 0.46 10.9 0.3 2.9 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) SKA1 PF07160.12 EKX40702.1 - 0.79 9.5 8.0 0.14 12.0 1.2 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF4164 PF13747.6 EKX40702.1 - 0.9 9.9 4.9 6 7.2 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) Spc42p PF11544.8 EKX40702.1 - 0.91 9.6 5.0 0.28 11.2 0.5 2.6 3 0 0 3 3 2 0 Spindle pole body component Spc42p Syntaxin_2 PF14523.6 EKX40702.1 - 1 9.8 6.6 0.14 12.5 0.5 2.4 2 1 1 3 3 3 0 Syntaxin-like protein zf-C4H2 PF10146.9 EKX40702.1 - 1.7 8.9 10.3 1.6 9.0 3.1 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein SlyX PF04102.12 EKX40702.1 - 1.9 9.1 7.1 5.3 7.7 0.4 4.1 2 1 2 4 4 4 0 SlyX THOC7 PF05615.13 EKX40702.1 - 2.4 8.4 10.2 0.72 10.1 0.4 3.1 2 2 1 3 3 3 0 Tho complex subunit 7 TMF_DNA_bd PF12329.8 EKX40702.1 - 2.7 8.1 8.6 0.19 11.8 1.4 2.8 3 0 0 3 3 2 0 TATA element modulatory factor 1 DNA binding Muted PF14942.6 EKX40702.1 - 3.4 8.0 11.8 0.21 11.9 1.8 2.5 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Spc24 PF08286.11 EKX40702.1 - 3.7 7.9 6.5 0.91 9.8 1.6 2.5 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 UPF0242 PF06785.11 EKX40702.1 - 6.6 6.8 12.3 0.48 10.5 5.0 2.5 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus RNA_pol_N PF01194.17 EKX40703.1 - 2.4e-27 95.0 2.5 2.8e-27 94.8 2.5 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit NTP_transf_7 PF07984.12 EKX40703.1 - 0.038 13.2 0.4 0.041 13.1 0.4 1.0 1 0 0 1 1 1 0 Nucleotidyltransferase VATC PF18716.1 EKX40703.1 - 0.041 13.8 0.6 0.041 13.8 0.6 2.2 1 1 1 2 2 2 0 Vms1-associating treble clef domain GCV_T PF01571.21 EKX40705.1 - 5.8e-82 274.9 0.1 1.1e-81 274.0 0.0 1.4 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EKX40705.1 - 3.5e-18 65.3 0.3 6.5e-18 64.4 0.3 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain POPLD PF08170.12 EKX40705.1 - 0.0062 16.9 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 POPLD (NUC188) domain SoxG PF04268.12 EKX40705.1 - 0.0095 16.1 0.0 0.082 13.1 0.0 2.1 2 0 0 2 2 2 1 Sarcosine oxidase, gamma subunit family TrmE_N PF10396.9 EKX40705.1 - 0.044 14.1 0.0 0.28 11.5 0.0 2.3 3 0 0 3 3 3 0 GTP-binding protein TrmE N-terminus MFS_1 PF07690.16 EKX40706.1 - 3.3e-18 65.7 58.9 2.4e-11 43.2 10.0 2.8 1 1 2 3 3 3 3 Major Facilitator Superfamily SL4P PF17618.2 EKX40709.1 - 0.031 14.3 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein GCV_T PF01571.21 EKX40710.1 - 4.6e-14 52.4 0.0 6.8e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Propep_M14 PF02244.16 EKX40710.1 - 0.11 12.8 0.0 0.25 11.8 0.0 1.7 1 1 0 1 1 1 0 Carboxypeptidase activation peptide RWP-RK PF02042.15 EKX40712.1 - 3.5e-11 42.9 0.0 5.4e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain P22_AR_N PF10547.9 EKX40712.1 - 0.0038 17.5 0.0 0.0051 17.1 0.0 1.3 1 0 0 1 1 1 1 P22_AR N-terminal domain HTH_6 PF01418.17 EKX40712.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family EGF_2 PF07974.13 EKX40713.1 - 4.7e-09 36.5 45.4 3.5e-06 27.3 9.0 3.4 3 0 0 3 3 3 2 EGF-like domain EGF PF00008.27 EKX40713.1 - 0.00017 21.8 35.1 0.013 15.8 6.9 3.6 3 0 0 3 3 3 2 EGF-like domain EGF_Tenascin PF18720.1 EKX40713.1 - 0.0011 18.9 9.2 0.0011 18.9 9.2 3.5 3 0 0 3 3 3 2 Tenascin EGF domain hEGF PF12661.7 EKX40713.1 - 0.0033 18.0 29.9 0.3 11.8 7.0 4.0 3 0 0 3 3 3 3 Human growth factor-like EGF Laminin_EGF PF00053.24 EKX40713.1 - 6.1 7.1 34.3 2.9 8.1 11.8 3.2 1 1 2 3 3 3 0 Laminin EGF domain DUF1943 PF09172.11 EKX40714.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Glyco_transf_8 PF01501.20 EKX40719.1 - 0.037 13.6 0.1 0.071 12.7 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 EKX40719.1 - 0.094 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.8 EKX40719.1 - 0.12 11.7 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Ion_trans PF00520.31 EKX40720.1 - 6.5e-24 84.5 10.0 9.7e-24 83.9 10.0 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX40720.1 - 1.7e-11 43.9 3.7 1.7e-11 43.9 3.7 2.4 2 1 1 3 3 3 1 Ion channel cNMP_binding PF00027.29 EKX40720.1 - 5.5e-06 26.4 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain RRM_2 PF04059.12 EKX40721.1 - 2.1e-46 156.1 0.1 2.7e-46 155.7 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 EKX40721.1 - 6.4e-05 22.7 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 EKX40721.1 - 0.002 18.3 0.1 0.0031 17.7 0.1 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 Smg4_UPF3 PF03467.15 EKX40721.1 - 0.0032 17.5 0.0 0.004 17.2 0.0 1.2 1 0 0 1 1 1 1 Smg-4/UPF3 family PHM7_cyt PF14703.6 EKX40721.1 - 0.042 14.1 0.1 0.18 12.1 0.0 1.9 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter PsbP PF01789.16 EKX40724.1 - 1.8e-18 67.2 0.0 2.1e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 PsbP GTP_EFTU PF00009.27 EKX40725.1 - 2.7e-57 193.5 0.0 5.3e-57 192.5 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 EKX40725.1 - 9.2e-19 67.3 0.0 2.4e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EKX40725.1 - 2e-11 44.1 0.0 5.2e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EKX40725.1 - 0.00058 19.9 0.1 0.0044 17.1 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EKX40725.1 - 0.0057 16.2 0.0 0.042 13.4 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 EKX40725.1 - 0.011 15.1 0.1 0.056 12.8 0.0 2.0 2 0 0 2 2 2 0 AIG1 family DUF442 PF04273.13 EKX40725.1 - 0.026 14.6 0.0 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 Putative phosphatase (DUF442) C4bp_oligo PF18453.1 EKX40725.1 - 0.058 13.6 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Oligomerization domain of C4b-binding protein alpha AvrPtoB_bdg PF16847.5 EKX40725.1 - 0.067 13.7 0.0 0.43 11.1 0.0 2.3 2 0 0 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain Val_tRNA-synt_C PF10458.9 EKX40725.1 - 0.11 12.8 0.3 0.25 11.7 0.3 1.5 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm Cyclin PF08613.11 EKX40726.1 - 1.6e-32 113.1 0.1 1.7e-32 113.0 0.1 1.0 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EKX40726.1 - 0.0013 18.5 0.0 0.0014 18.4 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF4149 PF13664.6 EKX40726.1 - 0.081 13.3 0.2 0.11 12.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) Arc_C PF18162.1 EKX40727.1 - 0.13 12.2 0.1 0.57 10.1 0.0 2.0 2 0 0 2 2 2 0 Arc C-lobe MatE PF01554.18 EKX40728.1 - 5.3e-54 182.2 27.5 4.3e-32 111.0 7.0 3.1 2 1 0 2 2 2 2 MatE TPT PF03151.16 EKX40730.1 - 3.5e-87 292.4 11.0 3.9e-87 292.3 11.0 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EKX40730.1 - 3.2e-07 30.6 19.0 5.5e-05 23.3 1.5 2.8 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EKX40730.1 - 1.8e-05 24.1 0.8 3.2e-05 23.3 0.8 1.4 1 0 0 1 1 1 1 UAA transporter family TMEM234 PF10639.9 EKX40730.1 - 0.025 14.6 3.0 7.1 6.7 2.5 3.0 2 1 0 2 2 2 0 Putative transmembrane family 234 C2 PF00168.30 EKX40731.1 - 0.0053 17.0 0.0 0.11 12.8 0.0 3.1 2 0 0 2 2 2 1 C2 domain SEP PF08059.13 EKX40733.1 - 1.3e-19 70.5 0.0 3.5e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 EKX40733.1 - 2.1e-12 47.0 0.0 3.6e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 UBX domain DUF1507 PF07408.11 EKX40734.1 - 0.088 12.7 0.3 0.19 11.6 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1507) PDZ_3 PF17815.1 EKX40735.1 - 1.3e-46 158.1 0.1 2.8e-46 157.0 0.1 1.6 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 EKX40735.1 - 9.7e-14 52.5 0.3 2.1e-13 51.4 0.3 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EKX40735.1 - 0.0003 20.6 0.1 0.00053 19.9 0.1 1.4 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 EKX40735.1 - 0.00031 21.0 0.0 0.00081 19.7 0.0 1.8 1 1 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX40735.1 - 0.0045 16.8 0.0 0.6 10.0 0.0 2.7 2 0 0 2 2 2 1 PDZ domain Ndc1_Nup PF09531.10 EKX40737.1 - 0.15 10.7 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UQ_con PF00179.26 EKX40740.1 - 6.6e-52 174.9 0.0 7.4e-52 174.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EKX40740.1 - 0.001 18.7 0.0 0.0012 18.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EKX40740.1 - 0.0062 16.8 0.0 0.008 16.4 0.0 1.3 1 0 0 1 1 1 1 RWD domain TPR_1 PF00515.28 EKX40741.1 - 1.8e-14 52.8 0.2 0.0031 17.3 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX40741.1 - 2.1e-13 49.3 1.2 0.11 12.6 0.0 7.5 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 EKX40741.1 - 6.1e-12 45.5 0.2 5.4e-05 23.3 0.0 4.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX40741.1 - 9.8e-12 45.2 3.1 0.00092 19.7 0.1 5.2 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 EKX40741.1 - 9.7e-11 41.8 5.0 0.26 11.6 0.0 6.5 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX40741.1 - 3.6e-10 39.2 1.1 1.1 9.6 0.0 7.5 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX40741.1 - 9.5e-10 38.5 5.6 0.18 12.7 0.0 7.3 5 2 3 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX40741.1 - 8.9e-08 31.6 5.3 0.0052 16.7 0.0 7.1 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX40741.1 - 1.8e-06 28.2 6.7 2.9 8.7 0.0 7.3 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX40741.1 - 9.1e-06 26.2 1.1 0.0099 16.5 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX40741.1 - 0.00015 21.4 1.2 0.056 13.1 0.0 4.1 4 0 0 4 4 4 1 TPR repeat TPR_20 PF14561.6 EKX40741.1 - 0.0052 17.1 0.2 0.48 10.8 0.3 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat F-box PF00646.33 EKX40741.1 - 0.024 14.5 0.0 5.8 6.9 0.0 2.4 2 0 0 2 2 2 0 F-box domain BTAD PF03704.17 EKX40741.1 - 0.053 14.0 0.1 2.1 8.8 0.0 3.1 1 1 2 3 3 3 0 Bacterial transcriptional activator domain TPR_MalT PF17874.1 EKX40741.1 - 0.096 12.0 2.8 7.3 5.9 0.0 3.1 1 1 0 3 3 3 0 MalT-like TPR region NARP1 PF12569.8 EKX40741.1 - 1.4 7.7 6.8 2.2 7.1 0.0 3.2 3 1 1 4 4 3 0 NMDA receptor-regulated protein 1 YL1 PF05764.13 EKX40741.1 - 2.9 8.0 9.7 4.8 7.2 9.7 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 EKX40741.1 - 7.1 4.7 7.6 12 3.9 7.6 1.3 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EKX40741.1 - 9.7 4.2 16.5 1.3 7.0 10.4 2.0 2 0 0 2 2 2 0 DNA polymerase phi E1-E2_ATPase PF00122.20 EKX40742.1 - 2.3e-37 128.2 1.9 2.3e-37 128.2 1.9 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EKX40742.1 - 2.3e-32 112.1 1.3 2.3e-32 112.1 1.3 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EKX40742.1 - 2.1e-14 54.3 0.2 6.5e-13 49.5 0.2 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EKX40742.1 - 1.7e-11 44.0 0.0 1.1e-10 41.5 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EKX40742.1 - 1.2e-05 25.2 0.5 0.00042 20.1 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EKX40742.1 - 0.00023 20.8 0.0 0.00043 19.9 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF4231 PF14015.6 EKX40742.1 - 3 8.4 4.7 3.4 8.2 0.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) LRR_6 PF13516.6 EKX40743.1 - 5.2e-12 44.8 11.1 0.011 15.7 0.1 5.7 5 0 0 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.7 EKX40743.1 - 1.1e-05 25.6 17.5 0.034 14.6 0.9 4.8 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) DUF4476 PF14771.6 EKX40743.1 - 0.00066 19.9 0.8 0.0088 16.3 0.5 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4476) LRR_1 PF00560.33 EKX40743.1 - 0.0077 16.6 13.0 4.5 8.2 0.3 5.6 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_8 PF13855.6 EKX40743.1 - 0.011 15.5 16.6 0.14 11.9 3.9 4.5 2 2 1 3 3 3 0 Leucine rich repeat Helicase_C PF00271.31 EKX40744.1 - 8.2e-12 45.5 0.0 2.1e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 EKX40744.1 - 3.7e-06 27.2 3.8 6.7e-06 26.4 0.3 2.9 2 1 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 EKX40744.1 - 2.6e-05 24.1 0.7 0.00041 20.1 0.7 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EKX40744.1 - 0.0003 21.1 0.1 0.00064 20.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EKX40744.1 - 0.0049 16.5 0.0 0.0087 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 EKX40744.1 - 0.0054 16.6 0.0 0.015 15.1 0.0 1.8 1 1 1 2 2 2 1 Helicase T2SSE PF00437.20 EKX40744.1 - 0.02 14.0 0.3 0.046 12.8 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.27 EKX40744.1 - 0.029 14.9 0.0 0.054 14.0 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 EKX40744.1 - 0.051 13.3 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EKX40744.1 - 0.064 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_14 PF13173.6 EKX40744.1 - 0.11 12.5 0.0 0.34 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EKX40744.1 - 0.12 12.8 0.1 0.22 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 EKX40744.1 - 0.15 12.0 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Sugar_tr PF00083.24 EKX40746.1 - 4.6e-23 81.8 21.8 3.7e-21 75.5 21.6 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EKX40746.1 - 2e-16 59.8 21.2 2e-16 59.8 21.2 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Gly-zipper_Omp PF13488.6 EKX40746.1 - 0.055 13.5 1.6 0.78 9.8 0.4 2.3 2 0 0 2 2 2 0 Glycine zipper ParBc_2 PF08857.11 EKX40747.1 - 4e-37 127.8 0.1 2.5e-35 122.0 0.1 2.1 1 1 0 1 1 1 1 Putative ParB-like nuclease Peptidase_M64 PF09471.10 EKX40747.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.6 1 1 0 1 1 1 0 IgA Peptidase M64 RRM_1 PF00076.22 EKX40748.1 - 7.8e-20 70.5 0.0 1e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_5 PF13857.6 EKX40749.1 - 2e-22 79.0 0.0 4.5e-09 36.4 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX40749.1 - 2.3e-20 72.7 0.0 2e-11 44.1 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX40749.1 - 7.3e-17 61.7 0.0 5e-16 59.1 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX40749.1 - 1.3e-15 57.0 0.0 3.8e-05 23.9 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EKX40749.1 - 3.3e-13 48.5 0.0 5.4e-05 23.3 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat TPR_2 PF07719.17 EKX40751.1 - 8.4e-09 34.9 1.4 0.0016 18.4 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX40751.1 - 7.8e-08 31.8 0.1 0.00014 21.5 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX40751.1 - 1.1e-07 32.3 0.1 1 9.9 0.0 5.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX40751.1 - 1.4e-07 31.2 0.2 0.021 15.0 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX40751.1 - 9.5e-07 29.4 3.1 0.00068 20.2 0.4 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX40751.1 - 1.9e-05 25.0 3.4 5.5 7.9 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX40751.1 - 5.7e-05 23.6 7.5 0.081 13.8 0.0 6.4 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX40751.1 - 0.00015 22.0 3.3 0.096 13.0 0.1 4.7 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX40751.1 - 0.0082 16.3 0.4 3.5 7.8 0.0 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat Haem_oxygenas_2 PF14518.6 EKX40751.1 - 0.098 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Iron-containing redox enzyme TPR_15 PF13429.6 EKX40751.1 - 0.31 10.2 3.0 0.58 9.3 0.1 2.8 3 1 1 4 4 4 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 EKX40752.1 - 9.5e-36 121.7 3.2 9e-18 64.2 0.1 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX40752.1 - 3.8e-27 94.3 4.1 1.3e-17 63.8 0.1 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EKX40752.1 - 1.2e-07 31.5 0.2 0.002 18.0 0.0 2.1 1 1 1 2 2 2 2 Myb DNA-binding like Rap1_C PF11626.8 EKX40752.1 - 0.00035 20.6 2.8 0.03 14.4 0.1 2.3 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 EKX40752.1 - 0.0022 18.1 1.8 0.34 11.1 0.3 2.9 1 1 1 2 2 2 2 Rap1 Myb domain Myb_DNA-bind_5 PF13873.6 EKX40752.1 - 0.14 12.3 7.2 23 5.2 0.0 3.8 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EKX40752.1 - 0.15 12.4 7.1 6.7 7.2 2.7 3.0 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain Skp1 PF01466.19 EKX40752.1 - 0.99 9.6 5.0 5.3 7.2 0.1 3.6 2 1 1 3 3 3 0 Skp1 family, dimerisation domain zf-U1 PF06220.12 EKX40754.1 - 3.9e-07 29.7 2.4 8.8e-07 28.6 2.4 1.6 1 0 0 1 1 1 1 U1 zinc finger GYF PF02213.16 EKX40754.1 - 0.017 14.8 0.5 0.11 12.1 0.0 2.6 2 0 0 2 2 2 0 GYF domain RseA_C PF03873.13 EKX40755.1 - 0.11 12.8 3.7 0.11 12.7 0.1 2.4 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain RVT_1 PF00078.27 EKX40758.1 - 1.8e-08 34.2 0.1 3.5e-08 33.3 0.1 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ABC1 PF03109.16 EKX40759.1 - 4.4e-33 114.0 0.0 8.3e-33 113.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Abhydrolase_2 PF02230.16 EKX40760.1 - 1.7e-32 113.0 0.0 3e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Patatin PF01734.22 EKX40760.1 - 5.4e-11 43.0 0.4 1.5e-09 38.4 0.0 2.9 2 1 0 3 3 3 1 Patatin-like phospholipase PH PF00169.29 EKX40760.1 - 1.8e-06 28.4 0.2 3.5e-06 27.5 0.2 1.5 1 0 0 1 1 1 1 PH domain Hydrolase_4 PF12146.8 EKX40760.1 - 0.00018 20.9 0.1 0.31 10.3 0.0 2.8 3 0 0 3 3 3 2 Serine aminopeptidase, S33 FSH1 PF03959.13 EKX40760.1 - 0.00094 18.9 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 EKX40760.1 - 0.0022 17.9 0.2 8.5 6.2 0.1 3.2 2 1 1 3 3 3 2 alpha/beta hydrolase fold PH_13 PF16652.5 EKX40760.1 - 0.053 13.3 0.2 0.1 12.4 0.2 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain Abhydrolase_6 PF12697.7 EKX40760.1 - 0.057 14.0 0.0 0.16 12.5 0.0 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.18 EKX40760.1 - 0.088 12.4 0.0 0.22 11.1 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family RVT_1 PF00078.27 EKX40761.1 - 1.8e-08 34.2 0.1 3.4e-08 33.3 0.1 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CK2S PF15011.6 EKX40762.1 - 0.019 14.8 0.0 0.022 14.7 0.0 1.1 1 0 0 1 1 1 0 Casein Kinase 2 substrate Pkinase PF00069.25 EKX40767.1 - 5.1e-53 180.1 0.0 5.7e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX40767.1 - 7.4e-40 136.9 0.0 9.7e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX40767.1 - 0.00017 20.5 0.0 0.00047 19.1 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EKX40767.1 - 0.0015 17.9 0.0 0.012 15.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Ald_Xan_dh_C PF01315.22 EKX40767.1 - 0.046 14.1 0.0 3.6 8.0 0.0 2.2 2 0 0 2 2 2 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Tyr_Deacylase PF02580.16 EKX40768.1 - 4.9e-37 127.6 0.0 6.3e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Ion_trans PF00520.31 EKX40769.1 - 2.3e-40 138.4 24.9 3.4e-40 137.8 24.9 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EKX40769.1 - 4e-08 32.4 20.0 9.4e-08 31.1 20.0 1.5 1 1 0 1 1 1 1 Polycystin cation channel DASH_Spc19 PF08287.11 EKX40769.1 - 0.65 9.9 5.2 1.8 8.4 5.2 1.8 1 0 0 1 1 1 0 Spc19 PhoU PF01895.19 EKX40771.1 - 0.00056 20.3 0.3 0.00098 19.5 0.3 1.4 1 0 0 1 1 1 1 PhoU domain TMEM51 PF15345.6 EKX40771.1 - 0.0077 16.1 2.8 0.0077 16.1 2.8 1.7 2 1 0 2 2 2 1 Transmembrane protein 51 H_kinase_N PF12282.8 EKX40771.1 - 0.022 14.7 0.1 0.044 13.7 0.1 1.5 1 0 0 1 1 1 0 Signal transduction histidine kinase PilJ PF13675.6 EKX40771.1 - 0.039 14.0 1.1 0.06 13.4 0.2 1.8 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Nsp1_C PF05064.13 EKX40771.1 - 0.06 13.1 2.5 0.12 12.1 2.4 1.5 1 1 0 1 1 1 0 Nsp1-like C-terminal region DnaJ_C PF01556.18 EKX40772.1 - 4.2e-24 85.3 0.1 6.2e-24 84.8 0.1 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EKX40772.1 - 3.6e-17 62.2 0.1 2.2e-16 59.7 0.0 2.2 2 0 0 2 2 2 1 DnaJ domain Band_7 PF01145.25 EKX40773.1 - 3.1e-33 115.3 0.1 5.3e-33 114.5 0.1 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 EKX40773.1 - 0.012 15.3 0.1 0.037 13.7 0.0 1.9 2 0 0 2 2 2 0 SPFH domain-Band 7 family Ribosomal_S3Ae PF01015.18 EKX40773.1 - 0.037 13.6 1.9 0.041 13.4 1.0 1.5 1 1 0 1 1 1 0 Ribosomal S3Ae family DUF908 PF06012.12 EKX40774.1 - 0.07 12.5 3.1 2.6 7.4 1.2 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) GBP_C PF02841.14 EKX40774.1 - 0.11 11.9 0.0 0.11 11.9 0.0 2.1 3 0 0 3 3 3 0 Guanylate-binding protein, C-terminal domain BNIP3 PF06553.12 EKX40774.1 - 0.36 10.5 7.0 3.6 7.2 3.3 2.4 2 0 0 2 2 2 0 BNIP3 XRCC4 PF06632.12 EKX40774.1 - 2.6 6.8 10.6 0.045 12.6 2.9 1.9 2 1 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Arm PF00514.23 EKX40775.1 - 4.3e-07 29.7 21.6 0.00067 19.6 0.0 6.6 7 1 0 7 7 7 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EKX40775.1 - 1.1e-05 25.4 4.9 0.061 13.4 0.4 4.0 1 1 3 4 4 4 2 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 EKX40775.1 - 0.0076 15.7 0.2 0.47 9.9 0.1 2.3 1 1 1 2 2 2 1 Armadillo-like CRS1_YhbY PF01985.21 EKX40775.1 - 0.0078 16.4 0.0 10 6.4 0.0 3.6 3 0 0 3 3 3 1 CRS1 / YhbY (CRM) domain APAF1_C PF17908.1 EKX40775.1 - 0.088 12.8 0.0 2.3 8.2 0.0 2.9 2 2 2 4 4 4 0 APAF-1 helical domain DUF3361 PF11841.8 EKX40775.1 - 0.089 12.7 1.1 2.2 8.2 0.3 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF3361) DUF3396 PF11876.8 EKX40775.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3396) ATG_C PF09333.11 EKX40775.1 - 0.13 12.6 0.1 0.3 11.4 0.1 1.5 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain DHO_dh PF01180.21 EKX40775.1 - 0.17 11.1 0.3 12 5.0 0.1 2.5 2 1 1 3 3 3 0 Dihydroorotate dehydrogenase HEAT_EZ PF13513.6 EKX40775.1 - 1.6 9.3 5.7 0.91 10.1 1.9 2.7 3 0 0 3 3 3 0 HEAT-like repeat Glyco_transf_41 PF13844.6 EKX40776.1 - 4.4e-71 239.7 0.0 1.2e-38 132.8 0.0 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_1 PF00515.28 EKX40776.1 - 8e-20 69.8 0.0 1.4e-06 27.8 0.0 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX40776.1 - 3.9e-18 64.0 0.0 0.00027 20.8 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX40776.1 - 7.9e-18 63.1 0.0 0.0002 21.3 0.1 4.8 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX40776.1 - 8.1e-13 48.5 0.2 3.4e-08 33.7 0.1 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX40776.1 - 2.7e-11 42.7 0.2 7.8e-05 22.4 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX40776.1 - 9e-09 34.9 0.4 0.00011 21.9 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX40776.1 - 4e-08 33.4 3.0 2.4 9.2 0.0 6.0 3 2 3 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX40776.1 - 1.1e-06 28.2 0.0 0.28 10.9 0.0 5.0 5 1 0 5 5 5 1 TPR repeat TPR_16 PF13432.6 EKX40776.1 - 1.7e-05 25.4 0.0 0.0055 17.3 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX40776.1 - 2.5e-05 24.7 0.3 0.081 13.4 0.1 3.6 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX40776.1 - 0.00028 21.1 0.0 19 5.9 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_15 PF13429.6 EKX40776.1 - 0.00063 19.0 0.1 0.003 16.8 0.1 2.1 2 1 0 2 2 2 1 Tetratricopeptide repeat NARP1 PF12569.8 EKX40776.1 - 0.0023 16.9 0.7 0.025 13.5 0.0 2.2 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 ANAPC3 PF12895.7 EKX40776.1 - 0.0038 17.4 0.0 0.061 13.5 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EKX40776.1 - 0.0039 17.3 0.0 2.5 8.3 0.0 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX40776.1 - 0.0076 16.8 0.9 0.31 11.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_5 PF12688.7 EKX40776.1 - 0.028 14.6 0.0 0.07 13.4 0.0 1.7 1 0 0 1 1 1 0 Tetratrico peptide repeat Proteasome_A_N PF10584.9 EKX40776.1 - 0.046 13.4 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature FSIP1 PF15554.6 EKX40777.1 - 0.02 14.0 0.1 0.027 13.6 0.1 1.2 1 0 0 1 1 1 0 FSIP1 family Mis14 PF08641.12 EKX40777.1 - 0.023 15.0 0.3 0.053 13.8 0.1 1.7 1 1 0 1 1 1 0 Kinetochore protein Mis14 like FANC_SAP PF18081.1 EKX40777.1 - 0.067 13.4 0.1 0.18 12.0 0.1 1.8 1 0 0 1 1 1 0 Fanconi anemia-associated nuclease SAP domain SDA1 PF05285.12 EKX40778.1 - 8.1e-11 41.9 36.6 1.9e-10 40.7 25.8 2.0 1 1 1 2 2 2 2 SDA1 DNA_pol_phi PF04931.13 EKX40778.1 - 0.033 12.3 19.1 0.037 12.2 19.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 EKX40778.1 - 0.054 11.8 14.6 0.054 11.8 14.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 EKX40778.1 - 0.36 9.3 10.1 0.42 9.1 10.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4366 PF14283.6 EKX40778.1 - 0.4 10.7 6.1 0.57 10.2 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) CobT PF06213.12 EKX40778.1 - 0.56 9.6 16.6 0.83 9.0 16.6 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Presenilin PF01080.17 EKX40778.1 - 3.7 6.2 4.7 3.5 6.3 4.7 1.2 1 0 0 1 1 1 0 Presenilin SDA1 PF05285.12 EKX40779.1 - 1.3e-17 64.2 46.2 1.3e-17 64.2 46.2 2.9 2 1 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 EKX40779.1 - 3.2e-17 62.6 0.3 3.2e-17 62.6 0.3 2.0 2 0 0 2 2 2 1 NUC130/3NT domain Cwf_Cwc_15 PF04889.12 EKX40779.1 - 0.0029 17.4 26.4 0.0029 17.4 26.4 2.5 2 1 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 EKX40779.1 - 0.95 7.5 43.2 0.064 11.4 35.3 2.3 2 1 0 2 2 2 0 DNA polymerase phi Epimerase PF01370.21 EKX40780.1 - 2.2e-17 63.3 0.0 1e-16 61.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EKX40780.1 - 8.7e-12 45.1 0.0 8.4e-09 35.3 0.0 2.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EKX40780.1 - 1e-06 28.8 0.0 1.6e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EKX40780.1 - 4.8e-05 23.0 0.0 7.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EKX40780.1 - 6.4e-05 22.1 0.0 0.00052 19.1 0.0 2.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EKX40780.1 - 0.0022 17.2 0.0 0.004 16.3 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain EF-hand_1 PF00036.32 EKX40781.1 - 1.7e-10 39.7 0.3 1.8e-05 23.9 0.1 2.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EKX40781.1 - 4.3e-09 35.6 0.1 0.0048 16.7 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EKX40781.1 - 5.1e-09 36.5 0.1 1.1e-08 35.4 0.1 1.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 EKX40781.1 - 4.8e-07 29.5 0.4 4.8e-06 26.3 0.0 2.2 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX40781.1 - 1.5e-05 24.3 0.7 0.00024 20.4 0.2 2.3 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.9 EKX40781.1 - 0.091 13.1 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region LRR_6 PF13516.6 EKX40782.1 - 7.5e-09 35.0 10.5 0.013 15.5 0.1 7.2 6 1 1 7 7 7 2 Leucine Rich repeat LRR_8 PF13855.6 EKX40782.1 - 0.0025 17.5 6.2 0.26 11.1 0.0 5.2 5 1 0 5 5 5 1 Leucine rich repeat LRR_1 PF00560.33 EKX40782.1 - 0.0057 17.0 0.7 1.4e+02 3.7 0.0 5.8 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.7 EKX40782.1 - 0.54 10.8 6.2 4.3 7.9 0.0 4.5 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 EKX40783.1 - 2.5e-19 69.6 0.0 2.7e-19 69.5 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain AP4E_app_platf PF14807.6 EKX40783.1 - 0.16 12.4 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Guanylate_cyc PF00211.20 EKX40784.1 - 1.5e-17 63.8 0.0 1.9e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LPD23 PF18838.1 EKX40785.1 - 0.17 11.6 0.1 21 5.0 0.0 2.3 2 0 0 2 2 2 0 Large polyvalent protein associated domain 23 IBN_N PF03810.19 EKX40787.1 - 5e-06 26.3 0.2 2.5e-05 24.1 0.1 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EKX40787.1 - 0.071 13.2 0.3 0.68 10.0 0.0 3.0 3 0 0 3 3 3 0 Exportin 1-like protein PDZ PF00595.24 EKX40788.1 - 4e-117 382.8 24.0 7.6e-10 39.0 0.1 14.5 14 0 0 14 14 14 14 PDZ domain PDZ_2 PF13180.6 EKX40788.1 - 1.4e-98 323.4 9.9 2.9e-09 37.1 0.2 14.2 14 0 0 14 14 14 13 PDZ domain PDZ_6 PF17820.1 EKX40788.1 - 1.1e-97 319.8 29.5 4.2e-09 36.1 0.1 14.4 14 0 0 14 14 14 13 PDZ domain Tricorn_PDZ PF14685.6 EKX40788.1 - 4.2e-31 106.8 24.8 0.011 15.7 0.0 14.2 14 0 0 14 14 14 9 Tricorn protease PDZ domain Presenilin PF01080.17 EKX40788.1 - 0.002 17.0 35.1 0.002 17.0 35.1 2.7 4 0 0 4 4 4 1 Presenilin AUX_IAA PF02309.16 EKX40788.1 - 0.19 11.6 17.3 0.016 15.1 11.8 2.0 2 0 0 2 2 2 0 AUX/IAA family GAGA_bind PF06217.12 EKX40788.1 - 0.32 11.2 22.7 1.1 9.5 22.7 1.8 1 0 0 1 1 1 0 GAGA binding protein-like family GREB1 PF15782.5 EKX40788.1 - 0.34 8.0 32.0 0.68 7.0 32.0 1.4 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PAT1 PF09770.9 EKX40788.1 - 0.34 9.1 56.0 0.59 8.3 56.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mem_trans PF03547.18 EKX40788.1 - 0.76 8.1 2.5 1.5 7.1 2.5 1.4 1 0 0 1 1 1 0 Membrane transport protein Hamartin PF04388.12 EKX40788.1 - 3 6.4 29.3 8.5 4.9 29.3 1.7 1 0 0 1 1 1 0 Hamartin protein DUF966 PF06136.13 EKX40788.1 - 5.7 6.5 26.8 0.88 9.2 21.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF966) TPR_14 PF13428.6 EKX40791.1 - 0.00097 19.8 0.9 3.7 8.6 0.2 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX40791.1 - 0.0016 18.9 1.6 0.05 14.1 1.4 3.2 1 1 1 2 2 2 1 Tetratricopeptide repeat ATP-synt_DE PF00401.20 EKX40791.1 - 0.031 14.5 1.9 0.053 13.8 0.4 2.3 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain HLH PF00010.26 EKX40791.1 - 0.033 14.1 0.3 0.13 12.3 0.3 2.0 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain MRP-L47 PF06984.13 EKX40791.1 - 0.034 14.3 0.2 0.087 12.9 0.2 1.7 1 0 0 1 1 1 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) TPR_2 PF07719.17 EKX40791.1 - 0.068 13.3 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Sulf_coat_C PF12193.8 EKX40791.1 - 0.091 12.8 9.0 2.2e+02 2.0 0.0 6.5 1 1 6 7 7 7 0 Sulfolobus virus coat protein C terminal TPR_17 PF13431.6 EKX40791.1 - 0.16 12.4 0.1 42 4.8 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Drf_FH1 PF06346.12 EKX40791.1 - 3.3 7.4 23.1 15 5.3 9.0 2.5 1 1 1 2 2 2 0 Formin Homology Region 1 DUF4634 PF15465.6 EKX40791.1 - 6.5 7.1 36.4 4.2 7.7 0.7 7.4 7 0 0 7 7 7 0 Domain of unknown function (DUF4634) Ank_4 PF13637.6 EKX40792.1 - 2.6e-11 43.8 0.4 7.3e-07 29.6 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX40792.1 - 5.5e-11 42.9 0.2 8.5e-11 42.3 0.2 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX40792.1 - 1.8e-09 37.7 0.1 3.2e-09 36.8 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) SH3_1 PF00018.28 EKX40792.1 - 1.4e-06 27.8 0.2 2.5e-05 23.8 0.2 2.4 1 1 0 1 1 1 1 SH3 domain Ank PF00023.30 EKX40792.1 - 2.3e-06 27.8 0.5 0.00035 20.9 0.1 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EKX40792.1 - 0.00024 21.3 0.2 0.041 14.4 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat SH3_2 PF07653.17 EKX40792.1 - 0.00036 20.2 0.0 0.0007 19.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EKX40792.1 - 0.0014 18.5 0.0 0.0038 17.0 0.0 1.8 1 1 0 1 1 1 1 Variant SH3 domain Ribosomal_L39 PF00832.20 EKX40793.1 - 2.2e-21 75.2 12.0 2.5e-21 75.0 12.0 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein SpoU_sub_bind PF08032.12 EKX40793.1 - 0.028 14.7 0.4 0.031 14.5 0.4 1.0 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding Ank_4 PF13637.6 EKX40794.1 - 5.5e-17 61.9 0.9 2.9e-08 34.1 0.1 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX40794.1 - 1.7e-16 60.5 0.0 1.5e-11 44.7 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EKX40794.1 - 2e-15 56.5 0.1 2.4e-09 37.2 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EKX40794.1 - 1.5e-14 53.8 0.1 1.8e-06 28.1 0.1 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX40794.1 - 3.8e-12 45.2 0.0 1.3e-08 34.4 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat NifU PF01106.17 EKX40795.1 - 1.1e-29 102.4 0.1 1.6e-29 101.8 0.1 1.2 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 EKX40795.1 - 2.2e-20 72.5 0.0 8.2e-20 70.7 0.0 1.9 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal HMD PF03201.16 EKX40795.1 - 0.13 12.5 0.0 0.45 10.8 0.0 1.8 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase F5_F8_type_C PF00754.25 EKX40796.1 - 5.3e-08 33.0 0.0 1.2e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain DUF3999 PF13163.6 EKX40796.1 - 0.0016 17.7 0.0 0.0023 17.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3999) Big_7 PF17957.1 EKX40797.1 - 0.13 13.1 0.0 0.25 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial Ig domain Eapp_C PF10238.9 EKX40798.1 - 0.011 15.8 4.4 0.011 15.8 4.4 1.7 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF3464 PF11947.8 EKX40798.1 - 0.35 10.6 14.1 0.079 12.7 10.2 1.8 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DUF4228 PF14009.6 EKX40798.1 - 0.38 11.1 4.3 0.18 12.2 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) Folate_carrier PF01770.18 EKX40798.1 - 3 6.5 6.6 5.1 5.7 6.6 1.3 1 0 0 1 1 1 0 Reduced folate carrier RPOL_N PF14700.6 EKX40798.1 - 4.9 6.5 17.6 2.6 7.3 9.5 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase N-terminal EF-hand_6 PF13405.6 EKX40800.1 - 1e-09 37.6 0.1 0.001 18.8 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EKX40800.1 - 3.7e-09 35.5 0.1 0.0018 17.7 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EKX40800.1 - 3.7e-07 30.5 1.0 2.9e-06 27.7 0.2 2.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX40800.1 - 0.00025 20.4 1.1 0.93 9.1 0.2 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EKX40800.1 - 0.0026 17.5 0.1 0.34 10.8 0.1 2.8 3 0 0 3 3 3 1 EF-hand domain pair WD40 PF00400.32 EKX40801.1 - 1.3e-09 38.4 18.2 0.04 14.8 0.0 9.8 10 0 0 10 10 10 2 WD domain, G-beta repeat HELP PF03451.14 EKX40801.1 - 2.9e-08 33.4 0.8 3.7e-07 29.9 0.8 2.5 1 1 0 1 1 1 1 HELP motif NifU_N PF01592.16 EKX40801.1 - 0.0029 17.7 0.1 0.027 14.6 0.2 2.2 2 0 0 2 2 2 1 NifU-like N terminal domain ANAPC4_WD40 PF12894.7 EKX40801.1 - 0.005 17.1 0.0 0.5 10.7 0.0 3.6 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX40801.1 - 0.046 12.7 1.7 0.31 10.0 0.0 3.1 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DNA_topoisoIV PF00521.20 EKX40804.1 - 1.8e-67 228.1 1.5 7.4e-57 193.1 0.3 2.5 1 1 1 2 2 2 2 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EKX40804.1 - 8e-35 119.9 9.4 8e-35 119.9 9.4 2.4 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EKX40804.1 - 1.9e-16 60.1 0.7 1.9e-16 60.1 0.7 2.6 2 0 0 2 2 2 1 DNA gyrase B Fer2 PF00111.27 EKX40804.1 - 1.7e-08 34.3 0.2 5e-08 32.8 0.2 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain HATPase_c PF02518.26 EKX40804.1 - 2.8e-08 34.3 0.0 7.3e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EKX40804.1 - 1.4e-05 25.3 0.0 4.7e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 Toprim domain DUF4467 PF14729.6 EKX40804.1 - 0.087 13.2 5.6 0.028 14.7 1.5 2.4 2 0 0 2 2 2 0 Domain of unknown function with cystatin-like fold (DUF4467) Inhibitor_I42 PF09394.10 EKX40805.1 - 2.3e-18 66.4 0.1 3.2e-18 65.9 0.1 1.2 1 0 0 1 1 1 1 Chagasin family peptidase inhibitor I42 DUF87 PF01935.17 EKX40806.1 - 0.0092 16.1 1.0 0.076 13.1 0.2 2.1 2 0 0 2 2 2 1 Helicase HerA, central domain Zot PF05707.12 EKX40806.1 - 0.018 14.7 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) MIOX PF05153.15 EKX40806.1 - 0.12 11.9 0.3 0.63 9.6 0.1 2.0 2 0 0 2 2 2 0 Myo-inositol oxygenase RPS31 PF17067.5 EKX40808.1 - 2e-05 24.7 3.6 2.1e-05 24.6 3.6 1.2 1 1 0 1 1 1 1 Ribosomal protein S31e Thx PF17070.5 EKX40808.1 - 0.0049 16.9 5.6 0.01 15.9 5.6 1.6 1 0 0 1 1 1 1 30S ribosomal protein Thx Phage_int_SAM_4 PF13495.6 EKX40809.1 - 0.27 11.7 1.2 1.5 9.4 0.1 2.8 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain Lipase_3 PF01764.25 EKX40810.1 - 3.5e-31 108.0 0.0 9.2e-31 106.6 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) Hydrolase_4 PF12146.8 EKX40810.1 - 0.0024 17.2 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EKX40810.1 - 0.015 15.0 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 EKX40810.1 - 0.024 15.2 0.0 0.088 13.4 0.0 1.8 1 1 1 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 EKX40810.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Cas_Cas4 PF01930.17 EKX40811.1 - 0.00015 21.9 0.7 0.026 14.6 0.1 3.0 3 0 0 3 3 3 2 Domain of unknown function DUF83 AA_permease_2 PF13520.6 EKX40812.1 - 3.5e-49 167.8 42.5 4.6e-49 167.4 42.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EKX40812.1 - 1.7e-31 109.3 44.2 2.5e-31 108.8 44.2 1.2 1 1 0 1 1 1 1 Amino acid permease AA_permease_C PF13906.6 EKX40812.1 - 1.8e-06 27.9 12.7 1.8e-06 27.9 12.7 4.1 5 0 0 5 5 5 1 C-terminus of AA_permease GTP_EFTU PF00009.27 EKX40813.1 - 1.8e-34 119.0 0.0 4.6e-34 117.7 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EKX40813.1 - 4.3e-20 71.8 0.1 1e-19 70.6 0.1 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 EKX40813.1 - 2e-14 53.2 0.1 5.2e-14 51.9 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 EKX40813.1 - 1.6e-11 44.4 2.7 1.7e-07 31.5 0.1 3.6 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EKX40813.1 - 2.2e-06 27.7 0.0 4.3e-05 23.6 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 EKX40813.1 - 0.00097 19.4 0.0 0.0022 18.2 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EKX40813.1 - 0.0084 15.7 0.0 0.03 13.9 0.0 2.0 1 1 0 1 1 1 1 Ras family ATP_bind_1 PF03029.17 EKX40813.1 - 0.011 15.5 0.0 0.052 13.3 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 EKX40813.1 - 0.019 15.2 0.6 0.13 12.5 0.1 2.6 2 1 0 2 2 2 0 AAA domain Mei5 PF10376.9 EKX40814.1 - 0.022 14.6 6.4 0.027 14.4 6.4 1.1 1 0 0 1 1 1 0 Double-strand recombination repair protein HEPN_MAE_28990 PF18737.1 EKX40814.1 - 0.18 11.7 5.9 0.23 11.4 5.9 1.0 1 0 0 1 1 1 0 MAE_28990/MAE_18760-like HEPN Pkinase PF00069.25 EKX40815.1 - 5.2e-41 140.7 0.0 6.2e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX40815.1 - 6.6e-18 64.9 0.0 8.3e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX40815.1 - 0.0012 18.2 0.1 0.0029 17.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EKX40815.1 - 0.005 16.8 0.0 0.0086 16.0 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX40815.1 - 0.0065 15.8 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EKX40815.1 - 0.0082 15.0 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EKX40815.1 - 0.011 15.3 0.2 0.13 11.8 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 BLM10_N PF16547.5 EKX40815.1 - 0.087 13.1 0.1 4.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Proteasome-substrate-size regulator, N-terminal PseudoU_synth_2 PF00849.22 EKX40816.1 - 0.00027 21.1 0.2 0.00041 20.5 0.2 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Pkinase PF00069.25 EKX40817.1 - 1.1e-65 221.6 0.0 1.4e-65 221.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX40817.1 - 1e-24 87.2 0.0 1.4e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX40817.1 - 0.00048 19.5 0.0 0.00084 18.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EKX40817.1 - 0.0019 17.8 0.0 0.016 14.8 0.0 2.0 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 EKX40817.1 - 0.0045 16.9 0.1 0.013 15.4 0.1 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EKX40817.1 - 0.038 13.6 0.0 0.063 12.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 EKX40817.1 - 0.038 13.3 0.0 0.25 10.6 0.0 2.0 1 1 0 1 1 1 0 Kinase-like Arm PF00514.23 EKX40818.1 - 0.0018 18.2 0.3 2.6 8.2 0.0 3.0 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat 3-alpha PF03475.14 EKX40819.1 - 0.098 12.5 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 3-alpha domain Y_phosphatase2 PF03162.13 EKX40821.1 - 2.6e-41 140.9 0.0 3.2e-41 140.6 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family DHHC PF01529.20 EKX40826.1 - 3.3e-16 59.6 10.9 3.9e-16 59.4 10.9 1.0 1 0 0 1 1 1 1 DHHC palmitoyltransferase PPDK_N PF01326.19 EKX40827.1 - 5.5e-34 117.9 0.6 1.9e-33 116.1 0.2 1.9 2 0 0 2 2 2 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain CBM_20 PF00686.19 EKX40827.1 - 1e-05 25.4 0.0 2.4e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Starch binding domain Pkinase_Tyr PF07714.17 EKX40828.1 - 8e-40 136.7 0.0 8.8e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX40828.1 - 1.4e-18 67.2 0.0 1.7e-18 67.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EKX40828.1 - 0.029 13.7 0.8 0.039 13.3 0.8 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YchF-GTPase_C PF06071.13 EKX40828.1 - 0.12 12.6 0.2 0.25 11.5 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF933) DUF3937 PF13073.6 EKX40828.1 - 0.24 11.6 0.1 0.42 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3937) Kinase-like PF14531.6 EKX40828.1 - 0.24 10.7 0.7 1.3 8.2 0.7 1.9 1 1 0 1 1 1 0 Kinase-like Ephrin_rec_like PF07699.13 EKX40829.1 - 7.3e-25 86.5 84.4 1.9e-08 34.0 8.2 5.8 1 1 5 7 7 7 6 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX40829.1 - 1.9e-09 37.8 37.6 0.035 14.5 0.9 6.5 2 1 4 7 7 7 7 TNFR/NGFR cysteine-rich region NCD3G PF07562.14 EKX40829.1 - 1.6e-08 34.4 40.4 0.0027 17.7 2.6 5.4 2 1 5 7 7 7 6 Nine Cysteines Domain of family 3 GPCR VSP PF03302.13 EKX40829.1 - 0.0033 16.3 41.0 0.11 11.3 15.5 2.5 1 1 0 2 2 2 2 Giardia variant-specific surface protein Opy2 PF09463.10 EKX40829.1 - 0.063 13.6 4.3 0.063 13.6 4.3 5.8 5 1 1 6 6 6 0 Opy2 protein Hyd_WA PF06462.12 EKX40829.1 - 0.11 12.5 1.5 18 5.4 0.1 3.6 3 0 0 3 3 3 0 Propeller SIR2 PF02146.17 EKX40830.1 - 0.084 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Sir2 family Abhydrolase_6 PF12697.7 EKX40831.1 - 2.5e-06 28.3 0.5 3.3e-06 27.8 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.12 EKX40831.1 - 0.025 13.6 0.0 0.036 13.1 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_3 PF07859.13 EKX40831.1 - 0.035 14.0 0.0 0.051 13.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Asp2 PF16929.5 EKX40831.1 - 0.077 12.0 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter Melibiase_2 PF16499.5 EKX40832.1 - 5.5e-45 153.7 0.3 7.2e-45 153.3 0.3 1.1 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EKX40832.1 - 5.9e-14 51.9 0.4 2.2e-13 50.0 0.1 2.2 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EKX40832.1 - 0.0066 15.5 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Melibiase Melibiase_2_C PF17450.2 EKX40832.1 - 0.04 14.1 0.0 0.22 11.8 0.0 2.3 1 1 0 1 1 1 0 Alpha galactosidase A C-terminal beta sandwich domain PI3_PI4_kinase PF00454.27 EKX40834.1 - 7e-37 127.6 0.0 9e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UBA_3 PF09288.10 EKX40836.1 - 0.015 15.1 0.4 1.9 8.4 0.0 2.6 1 1 1 2 2 2 0 Fungal ubiquitin-associated domain Mre11_DNA_bind PF04152.14 EKX40836.1 - 0.13 12.6 5.0 2.2 8.6 2.5 3.2 1 1 0 2 2 2 0 Mre11 DNA-binding presumed domain Mog1 PF04603.12 EKX40836.1 - 0.35 11.2 4.6 2 8.8 1.3 2.5 2 1 0 2 2 2 0 Ran-interacting Mog1 protein FUSC PF04632.12 EKX40836.1 - 0.42 9.1 21.7 0.34 9.4 6.2 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family DMRT-like PF15791.5 EKX40836.1 - 3 8.3 10.8 50 4.3 3.6 3.7 1 1 2 3 3 3 0 Doublesex-and mab-3-related transcription factor C1 and C2 TPR_2 PF07719.17 EKX40838.1 - 3.9e-36 120.3 3.9 5.4e-06 26.1 0.2 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 EKX40838.1 - 5.5e-35 118.8 5.0 1.5e-10 40.6 1.5 6.9 2 1 5 7 7 7 6 TPR repeat TPR_1 PF00515.28 EKX40838.1 - 1.8e-32 109.8 4.7 1.1e-07 31.3 0.1 7.2 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 EKX40838.1 - 5.1e-28 94.9 8.2 7e-06 25.8 0.6 7.7 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 EKX40838.1 - 5.9e-28 97.2 5.3 2.6e-10 40.8 0.8 4.3 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 EKX40838.1 - 2.7e-27 95.0 17.3 8.6e-07 29.4 2.1 4.9 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.6 EKX40838.1 - 3.1e-27 92.9 3.1 0.00035 20.7 0.0 6.6 7 0 0 7 7 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 EKX40838.1 - 3e-22 76.9 4.8 8.3e-05 22.4 0.1 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 EKX40838.1 - 2.1e-21 76.0 14.9 6e-07 29.7 3.3 5.3 2 1 4 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 EKX40838.1 - 1.1e-19 69.4 7.9 0.00078 20.1 0.4 6.8 1 1 6 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 EKX40838.1 - 1.1e-16 60.1 16.3 0.0006 19.6 0.4 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.6 EKX40838.1 - 1.1e-12 47.7 7.4 0.01 16.4 0.1 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX40838.1 - 1.4e-10 41.1 0.3 0.00065 19.2 0.0 3.1 1 1 2 3 3 3 3 MalT-like TPR region TPR_15 PF13429.6 EKX40838.1 - 2.2e-09 36.9 3.5 1.7e-05 24.2 0.2 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX40838.1 - 3.1e-08 33.7 3.2 0.0017 18.5 0.5 4.0 2 1 3 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX40838.1 - 3.2e-07 30.5 3.7 0.0025 18.0 0.1 3.5 1 1 4 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 EKX40838.1 - 3.8e-06 27.0 13.3 3.2 8.6 0.4 6.9 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_21 PF09976.9 EKX40838.1 - 1.2e-05 25.1 3.3 1.2e-05 25.1 3.3 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat-like domain NARP1 PF12569.8 EKX40838.1 - 1.9e-05 23.8 1.3 0.29 10.0 0.1 3.0 1 1 1 3 3 3 2 NMDA receptor-regulated protein 1 FAT PF02259.23 EKX40838.1 - 0.00028 20.2 0.4 0.51 9.5 0.4 3.1 1 1 2 3 3 3 2 FAT domain DUF3808 PF10300.9 EKX40838.1 - 0.00064 18.6 0.1 0.00097 18.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) BTAD PF03704.17 EKX40838.1 - 0.0017 18.8 4.8 0.012 16.0 3.4 2.4 1 1 1 2 2 2 1 Bacterial transcriptional activator domain Coatomer_E PF04733.14 EKX40838.1 - 0.0023 17.4 0.7 0.92 8.9 0.1 2.5 1 1 2 3 3 3 2 Coatomer epsilon subunit TPR_20 PF14561.6 EKX40838.1 - 0.011 16.1 1.5 3.6 8.0 0.1 3.9 1 1 1 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 EKX40838.1 - 0.016 15.4 1.5 41 4.7 0.0 4.8 5 0 0 5 5 4 0 PPR repeat Clathrin PF00637.20 EKX40838.1 - 0.025 14.5 0.1 0.19 11.6 0.0 2.2 2 1 0 2 2 2 0 Region in Clathrin and VPS TOM20_plant PF06552.12 EKX40838.1 - 0.049 13.4 0.0 0.14 11.9 0.0 1.9 1 1 1 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 HemY_N PF07219.13 EKX40838.1 - 0.05 13.8 8.0 0.15 12.2 0.4 3.1 1 1 3 4 4 4 0 HemY protein N-terminus YfiO PF13525.6 EKX40838.1 - 0.052 13.3 4.7 0.23 11.1 1.7 2.8 2 1 1 3 3 3 0 Outer membrane lipoprotein Tcf25 PF04910.14 EKX40838.1 - 0.062 12.4 0.1 1.7 7.6 0.0 2.1 1 1 1 2 2 2 0 Transcriptional repressor TCF25 ANAPC5 PF12862.7 EKX40838.1 - 0.12 12.5 0.4 3.4 7.8 0.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 Mad3_BUB1_I PF08311.12 EKX40838.1 - 0.2 11.6 1.3 8.9 6.3 0.1 2.8 3 0 0 3 3 2 0 Mad3/BUB1 homology region 1 TPR_3 PF07720.12 EKX40838.1 - 0.23 11.5 3.6 7.7 6.6 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat RPN7 PF10602.9 EKX40838.1 - 0.49 10.1 3.3 4.7 6.9 0.2 3.0 1 1 3 4 4 4 0 26S proteasome subunit RPN7 TPR_11 PF13414.6 EKX40839.1 - 1.7e-10 40.4 2.2 0.0065 16.1 0.0 4.5 4 0 0 4 4 4 3 TPR repeat TPR_17 PF13431.6 EKX40839.1 - 2e-08 34.0 3.5 0.0047 17.2 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX40839.1 - 2.4e-08 33.4 3.9 0.016 15.0 0.0 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX40839.1 - 3.7e-07 29.7 0.9 0.96 9.7 0.0 5.5 5 1 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX40839.1 - 5.8e-06 26.1 3.4 0.13 12.5 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX40839.1 - 1.7e-05 25.0 5.2 0.012 15.9 0.1 3.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX40839.1 - 2.2e-05 24.2 11.2 0.015 15.2 0.1 4.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX40839.1 - 6e-05 23.5 0.1 0.029 15.2 0.0 3.6 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX40839.1 - 6.5e-05 23.5 0.0 0.00077 20.1 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat Nop14 PF04147.12 EKX40839.1 - 0.013 13.7 24.7 0.02 13.1 24.7 1.3 1 0 0 1 1 1 0 Nop14-like family TPR_19 PF14559.6 EKX40839.1 - 0.013 16.0 0.6 0.073 13.6 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat BUD22 PF09073.10 EKX40839.1 - 0.38 10.0 24.9 0.078 12.3 21.5 1.7 2 0 0 2 2 2 0 BUD22 SAPS PF04499.15 EKX40839.1 - 4.2 6.0 8.9 5.8 5.6 8.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Tropomyosin_1 PF12718.7 EKX40840.1 - 0.0067 16.6 7.9 0.0067 16.6 7.9 3.8 1 1 1 3 3 3 1 Tropomyosin like RRP36 PF06102.12 EKX40840.1 - 0.012 15.6 2.0 0.012 15.6 2.0 4.6 3 1 1 4 4 4 0 rRNA biogenesis protein RRP36 Imm30 PF15565.6 EKX40840.1 - 0.017 15.2 1.6 0.017 15.2 1.6 3.0 3 0 0 3 3 3 0 Immunity protein 30 NPV_P10 PF05531.12 EKX40840.1 - 0.85 10.1 12.9 1.1 9.7 1.8 4.0 2 2 3 5 5 5 0 Nucleopolyhedrovirus P10 protein Hemagglutinin PF00509.18 EKX40840.1 - 3 6.1 7.1 0.1 11.0 0.9 1.5 2 0 0 2 2 2 0 Haemagglutinin Sugarporin_N PF11471.8 EKX40840.1 - 5.5 7.0 11.2 0.1 12.6 1.1 2.7 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension DUF1664 PF07889.12 EKX40840.1 - 9.8 6.2 27.7 0.63 10.1 1.9 3.9 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) DUF4483 PF14825.6 EKX40841.1 - 0.0099 15.6 1.1 0.011 15.4 1.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4483) EGF_2 PF07974.13 EKX40842.1 - 0.00062 20.1 12.3 0.00062 20.1 12.3 2.0 2 0 0 2 2 2 1 EGF-like domain EGF PF00008.27 EKX40842.1 - 0.39 11.1 5.1 0.78 10.1 5.1 1.5 1 0 0 1 1 1 0 EGF-like domain DSL PF01414.19 EKX40842.1 - 0.45 10.8 12.2 0.82 10.0 12.2 1.4 1 0 0 1 1 1 0 Delta serrate ligand GST_N_3 PF13417.6 EKX40843.1 - 4.4e-14 52.7 0.0 7.6e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EKX40843.1 - 6.8e-14 52.0 0.0 1.2e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EKX40843.1 - 1.7e-10 41.0 0.0 3.3e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EKX40843.1 - 4.3e-05 23.5 0.0 7.8e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EKX40843.1 - 0.00038 20.6 0.0 0.0014 18.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EKX40843.1 - 0.017 15.3 0.0 0.11 12.7 0.0 2.3 2 0 0 2 2 2 0 Glutaredoxin FAA_hydrolase PF01557.18 EKX40844.1 - 2.3e-52 177.8 0.0 3.3e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 EKX40844.1 - 2.5e-26 92.0 0.0 4.1e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Glycos_transf_2 PF00535.26 EKX40846.1 - 0.00085 19.2 0.0 0.0031 17.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 2 PKD_channel PF08016.12 EKX40847.1 - 3.1e-66 223.8 17.6 4.2e-66 223.4 17.6 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 EKX40847.1 - 7.9e-16 58.0 28.2 9.2e-16 57.8 23.2 2.1 2 0 0 2 2 2 2 Ion transport protein GST_N_3 PF13417.6 EKX40848.1 - 0.00029 21.2 0.0 0.0088 16.4 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EKX40848.1 - 0.018 15.1 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Imm74 PF15603.6 EKX40849.1 - 0.099 12.9 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Immunity protein 74 Beta_helix PF13229.6 EKX40850.1 - 3.9e-13 49.5 6.2 2.9e-07 30.5 0.1 2.4 1 1 1 2 2 2 2 Right handed beta helix region PDZ_6 PF17820.1 EKX40850.1 - 1.9e-12 46.8 0.0 5.7e-12 45.3 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX40850.1 - 5.1e-06 26.7 0.0 1.4e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX40850.1 - 1.5e-05 25.2 0.1 0.00011 22.5 0.0 2.5 2 0 0 2 2 2 1 PDZ domain WD40 PF00400.32 EKX40851.1 - 4.5e-10 39.9 12.8 0.00019 22.1 0.5 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Hira PF07569.11 EKX40851.1 - 0.17 11.6 0.1 13 5.5 0.0 2.4 2 0 0 2 2 2 0 TUP1-like enhancer of split Hydrolase_4 PF12146.8 EKX40853.1 - 1.2e-08 34.5 0.1 0.00032 20.1 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EKX40853.1 - 6e-05 23.8 1.1 0.0079 16.8 1.4 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EKX40853.1 - 0.00031 20.5 0.1 0.045 13.4 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 EKX40853.1 - 0.0027 17.4 0.0 0.0038 16.9 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 EKX40853.1 - 0.021 14.4 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 EKX40853.1 - 0.034 13.6 0.0 0.069 12.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF1057 PF06342.12 EKX40853.1 - 0.048 12.7 0.0 0.12 11.4 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Carn_acyltransf PF00755.20 EKX40854.1 - 5.6e-173 576.7 0.0 6.5e-173 576.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Cys_rich_VLP PF14194.6 EKX40855.1 - 0.094 12.9 0.3 0.24 11.6 0.0 1.8 2 0 0 2 2 2 0 Cysteine-rich VLP SWIM PF04434.17 EKX40855.1 - 0.13 12.0 0.7 0.29 10.8 0.7 1.6 1 0 0 1 1 1 0 SWIM zinc finger MCPVI PF02993.14 EKX40855.1 - 1.6 8.5 4.0 3.5 7.4 4.0 1.5 1 0 0 1 1 1 0 Minor capsid protein VI Stealth_CR3 PF17102.5 EKX40855.1 - 2.9 7.9 4.9 5.1 7.1 0.1 3.1 3 0 0 3 3 3 0 Stealth protein CR3, conserved region 3 GCS PF03074.16 EKX40856.1 - 1.4e-149 498.4 0.5 1.9e-149 498.0 0.0 1.4 2 0 0 2 2 2 1 Glutamate-cysteine ligase GCS2 PF04107.13 EKX40856.1 - 0.029 13.7 0.0 0.077 12.3 0.0 1.7 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) Hist_deacetyl PF00850.19 EKX40857.1 - 5.8e-44 150.8 0.0 8.8e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DUF4123 PF13503.6 EKX40857.1 - 0.15 12.5 0.0 19 5.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4123) Ank_4 PF13637.6 EKX40858.1 - 4.4e-81 266.3 16.8 5.7e-08 33.2 0.0 17.4 11 7 7 19 19 19 18 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX40858.1 - 1.3e-65 217.9 12.1 8.6e-08 32.7 0.1 10.0 1 1 11 12 12 12 12 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX40858.1 - 1e-32 111.8 31.2 0.0056 17.0 0.1 16.1 5 5 11 17 17 17 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX40858.1 - 4e-27 91.3 2.5 0.024 15.2 0.1 15.5 18 0 0 18 18 18 2 Ankyrin repeat Chol_subst-bind PF09129.11 EKX40858.1 - 2.8e-11 43.0 0.0 0.53 9.2 0.0 10.2 4 2 9 13 13 13 1 Cholesterol oxidase, substrate-binding Ank PF00023.30 EKX40858.1 - 5.9e-09 36.0 21.5 0.001 19.4 0.2 12.7 16 0 0 16 16 16 1 Ankyrin repeat Hva1_TUDOR PF11160.8 EKX40858.1 - 0.0025 18.0 0.2 4.8e+02 1.0 0.0 8.2 13 0 0 13 13 13 0 Hypervirulence associated proteins TUDOR domain RTP1_C2 PF10304.9 EKX40858.1 - 0.48 10.2 6.8 27 4.6 0.2 5.3 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 2 MerR-DNA-bind PF09278.11 EKX40858.1 - 1.6 9.3 17.2 3.3e+02 1.9 0.0 9.8 12 0 0 12 12 12 0 MerR, DNA binding ART PF01129.18 EKX40859.1 - 5.7e-08 32.3 0.0 6.7e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase ADPrib_exo_Tox PF03496.14 EKX40859.1 - 1.3e-06 27.9 0.0 1.6e-06 27.6 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosyltransferase exoenzyme Nse5 PF08691.10 EKX40860.1 - 0.11 11.2 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 FtsJ PF01728.19 EKX40861.1 - 6.1e-17 62.3 0.0 7.1e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Cnn_1N PF07989.11 EKX40863.1 - 0.041 14.0 0.4 0.041 14.0 0.4 5.0 4 1 0 5 5 5 0 Centrosomin N-terminal motif 1 TetR_C_6 PF13977.6 EKX40863.1 - 0.59 10.4 5.5 0.54 10.5 1.1 2.5 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal Bromodomain PF00439.25 EKX40865.1 - 2.3e-16 59.6 0.0 4e-16 58.9 0.0 1.4 1 1 0 1 1 1 1 Bromodomain UPF0225 PF17775.1 EKX40866.1 - 2.6e-08 34.6 39.1 0.58 11.0 1.1 7.6 6 0 0 6 6 6 6 UPF0225 domain ThrE PF06738.12 EKX40866.1 - 3.2e-07 30.0 16.7 0.7 9.2 0.3 6.7 6 0 0 6 6 6 4 Putative threonine/serine exporter Rop-like PF05082.13 EKX40866.1 - 0.00046 20.0 9.9 14 5.6 0.1 7.3 6 0 0 6 6 6 1 Rop-like Fib_alpha PF08702.10 EKX40866.1 - 0.0007 19.8 56.0 0.59 10.3 0.0 11.9 11 1 1 12 12 12 3 Fibrinogen alpha/beta chain family Rab5-bind PF09311.11 EKX40866.1 - 0.0019 17.6 132.7 0.0026 17.2 2.8 10.7 7 4 4 11 11 11 6 Rabaptin-like protein Epsilon_antitox PF08998.11 EKX40866.1 - 1.7 9.0 7.8 0.15 12.3 0.5 3.2 3 0 0 3 3 3 0 Bacterial epsilon antitoxin tRNA-synt_2b PF00587.25 EKX40866.1 - 4.9 7.1 26.6 0.12 12.3 0.3 7.1 5 3 1 7 7 7 0 tRNA synthetase class II core domain (G, H, P, S and T) Spc7 PF08317.11 EKX40866.1 - 9.1 5.1 149.7 0.13 11.1 9.9 11.7 5 3 7 12 12 12 0 Spc7 kinetochore protein PH PF00169.29 EKX40869.1 - 9.3e-05 22.9 0.1 0.00013 22.4 0.1 1.2 1 0 0 1 1 1 1 PH domain DUF5511 PF17630.2 EKX40869.1 - 0.055 13.7 0.1 0.13 12.5 0.1 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5511) Sel1 PF08238.12 EKX40869.1 - 0.11 13.2 0.1 0.23 12.2 0.1 1.6 1 0 0 1 1 1 0 Sel1 repeat MscS_porin PF12795.7 EKX40871.1 - 0.0016 18.1 23.0 0.0016 18.1 23.0 3.2 3 0 0 3 3 3 1 Mechanosensitive ion channel porin domain Filament PF00038.21 EKX40871.1 - 0.0064 16.1 43.1 0.061 12.9 18.6 3.2 3 1 0 3 3 3 2 Intermediate filament protein DASH_Duo1 PF08651.10 EKX40871.1 - 0.0099 15.6 1.9 0.06 13.1 0.1 3.4 3 0 0 3 3 3 1 DASH complex subunit Duo1 Mig-14 PF07395.11 EKX40871.1 - 0.011 15.1 1.6 0.045 13.1 1.6 2.0 1 0 0 1 1 1 0 Mig-14 NTS PF15447.6 EKX40871.1 - 0.098 13.2 5.7 0.15 12.6 0.5 3.0 2 0 0 2 2 2 0 N-terminal segments of PfEMP1 FUSC PF04632.12 EKX40871.1 - 0.79 8.2 19.8 0.49 8.9 11.1 2.2 1 1 1 2 2 2 0 Fusaric acid resistance protein family Tup_N PF08581.10 EKX40871.1 - 2.4 8.5 37.6 4 7.8 2.1 6.8 4 3 3 7 7 7 0 Tup N-terminal Allexi_40kDa PF05549.11 EKX40871.1 - 2.6 7.5 16.6 0.15 11.6 7.4 2.8 1 1 1 3 3 3 0 Allexivirus 40kDa protein AraC_binding PF02311.19 EKX40871.1 - 2.8 7.9 4.0 8.9 6.2 0.2 3.1 3 0 0 3 3 3 0 AraC-like ligand binding domain U-box PF04564.15 EKX40873.1 - 3.2e-08 33.6 0.0 3.4e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX40873.1 - 4.5e-06 26.4 0.0 5.9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 EKX40873.1 - 0.0001 22.3 0.0 0.00011 22.3 0.0 1.1 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 EKX40873.1 - 0.022 14.8 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EKX40873.1 - 0.04 13.7 0.0 0.05 13.5 0.0 1.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Acyl-CoA_ox_N PF14749.6 EKX40874.1 - 0.065 13.8 0.9 0.095 13.2 0.9 1.3 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Glyco_transf_10 PF00852.19 EKX40875.1 - 4.2e-33 114.5 0.1 5.3e-33 114.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Exostosin PF03016.15 EKX40875.1 - 0.00049 19.4 0.0 0.00066 19.0 0.0 1.2 1 0 0 1 1 1 1 Exostosin family Glyco_trans_1_2 PF13524.6 EKX40875.1 - 0.023 15.1 0.1 0.044 14.2 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Sel1 PF08238.12 EKX40878.1 - 5.3e-16 58.7 10.1 0.0038 17.8 0.0 7.6 7 0 0 7 7 7 4 Sel1 repeat NTP_transf_3 PF12804.7 EKX40878.1 - 0.071 13.5 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain DDT PF02791.17 EKX40879.1 - 0.00074 19.8 0.0 0.0021 18.3 0.0 1.8 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 EKX40879.1 - 0.00077 18.9 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Pkinase PF00069.25 EKX40880.1 - 7.3e-26 91.1 0.0 9.4e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX40880.1 - 2.7e-13 49.8 0.0 3.3e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX40880.1 - 6.3e-06 25.2 0.1 8.6e-06 24.8 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX40880.1 - 0.00084 19.3 0.0 0.046 13.6 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Aldedh PF00171.22 EKX40881.1 - 6.1e-111 371.2 5.3 2.2e-88 296.8 0.5 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family YCII PF03795.14 EKX40881.1 - 0.14 12.6 0.0 0.37 11.2 0.0 1.8 1 1 0 1 1 1 0 YCII-related domain DUF5053 PF16476.5 EKX40881.1 - 0.15 11.7 0.1 0.8 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5053) C2 PF00168.30 EKX40882.1 - 4.8e-18 65.3 0.0 1e-10 41.8 0.0 2.3 2 0 0 2 2 2 2 C2 domain PDZ_6 PF17820.1 EKX40882.1 - 1.9e-10 40.4 0.0 4.4e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX40882.1 - 2.4e-07 31.0 0.0 7.7e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX40882.1 - 1.6e-05 25.1 0.1 0.0001 22.5 0.1 2.3 1 1 1 2 2 2 1 PDZ domain PI3K_C2 PF00792.24 EKX40882.1 - 0.0048 16.8 0.0 0.033 14.1 0.0 2.1 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 Tricorn_PDZ PF14685.6 EKX40882.1 - 0.0081 16.1 0.0 0.024 14.6 0.0 1.8 1 0 0 1 1 1 1 Tricorn protease PDZ domain SNF5 PF04855.12 EKX40883.1 - 3.2e-12 46.7 1.8 3.2e-12 46.7 1.8 3.0 3 1 0 3 3 3 1 SNF5 / SMARCB1 / INI1 BSP_II PF05432.11 EKX40883.1 - 0.74 9.4 28.8 2.4 7.8 28.8 1.9 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) LRR_4 PF12799.7 EKX40884.1 - 2.8e-22 78.4 30.7 2.2e-07 31.1 2.3 6.4 3 1 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX40884.1 - 3.1e-21 74.9 23.8 1.3e-08 34.5 4.6 5.8 1 1 4 5 5 5 5 Leucine rich repeat LRR_1 PF00560.33 EKX40884.1 - 2.4e-05 24.2 18.5 0.34 11.6 0.1 7.8 7 2 0 7 7 7 2 Leucine Rich Repeat LRR_9 PF14580.6 EKX40884.1 - 0.003 17.1 13.1 0.1 12.1 4.0 3.1 1 1 3 4 4 4 3 Leucine-rich repeat LRR_5 PF13306.6 EKX40884.1 - 0.0033 17.4 2.1 1.4 8.9 0.1 3.3 2 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) DnaJ_CXXCXGXG PF00684.19 EKX40885.1 - 6.8e-08 32.8 138.3 0.0043 17.4 26.0 6.3 1 1 3 5 5 5 4 DnaJ central domain Anoctamin PF04547.12 EKX40886.1 - 9.8e-93 311.4 2.5 9.8e-93 311.4 2.5 1.5 2 0 0 2 2 2 1 Calcium-activated chloride channel PDZ_6 PF17820.1 EKX40886.1 - 1.8e-09 37.3 0.0 4e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX40886.1 - 1.4e-07 31.8 0.0 3.2e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain TPR_17 PF13431.6 EKX40886.1 - 3.5e-07 30.2 0.4 0.31 11.5 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat PDZ PF00595.24 EKX40886.1 - 1.2e-06 28.8 0.0 2.8e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PH PF00169.29 EKX40886.1 - 6.9e-06 26.5 0.5 2.2e-05 24.9 0.5 1.9 1 0 0 1 1 1 1 PH domain TPR_16 PF13432.6 EKX40886.1 - 0.00078 20.0 0.2 1.5 9.5 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX40886.1 - 0.0012 19.5 1.0 0.042 14.7 0.1 3.8 3 1 2 5 5 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX40886.1 - 0.0013 18.7 0.5 0.95 9.7 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX40886.1 - 0.003 17.3 0.4 0.53 10.2 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX40886.1 - 0.012 15.9 0.7 0.046 14.0 0.2 2.2 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EKX40886.1 - 0.059 13.4 3.5 3.1 8.0 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat SLATT_5 PF18160.1 EKX40886.1 - 0.19 11.0 0.9 0.57 9.5 0.1 2.3 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 eIF-3c_N PF05470.12 EKX40887.1 - 1.1 7.5 10.5 1.5 7.1 10.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF4207 PF13904.6 EKX40887.1 - 2.3 7.9 20.6 0.26 10.9 4.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) EIIBC-GUT_N PF03612.14 EKX40887.1 - 8.1 6.2 11.1 1.6 8.4 1.0 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus ubiquitin PF00240.23 EKX40888.1 - 1.6e-13 50.2 0.1 2.7e-13 49.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EKX40888.1 - 0.00045 20.0 0.1 0.00086 19.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like EGF_2 PF07974.13 EKX40889.1 - 9.3e-15 54.7 104.7 0.00069 19.9 10.5 6.3 6 0 0 6 6 6 6 EGF-like domain EGF PF00008.27 EKX40889.1 - 9.3e-10 38.6 74.7 7.4e-05 23.0 6.1 6.8 6 0 0 6 6 6 5 EGF-like domain hEGF PF12661.7 EKX40889.1 - 0.061 14.0 2.6 0.061 14.0 2.6 7.7 8 0 0 8 8 8 0 Human growth factor-like EGF GLTP PF08718.11 EKX40890.1 - 0.027 14.7 0.1 0.063 13.5 0.1 1.6 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) F5_F8_type_C PF00754.25 EKX40890.1 - 0.19 11.8 0.0 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 F5/8 type C domain DUF4897 PF16238.5 EKX40891.1 - 0.015 15.2 0.0 0.039 13.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4897) DUF2188 PF09954.9 EKX40891.1 - 0.053 13.7 0.9 0.18 12.0 0.9 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) Nucleoside_tran PF01733.18 EKX40892.1 - 0.02 14.3 0.0 0.029 13.8 0.0 1.1 1 0 0 1 1 1 0 Nucleoside transporter DHHC PF01529.20 EKX40894.1 - 2.8e-37 127.8 17.2 2.8e-37 127.8 17.2 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase EF-hand_7 PF13499.6 EKX40896.1 - 7.1e-10 39.2 0.5 1.3e-09 38.4 0.5 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX40896.1 - 3e-07 29.8 2.7 5.8e-06 25.8 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 EKX40896.1 - 9.9e-07 28.5 0.8 0.00013 21.7 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX40896.1 - 2.2e-06 26.8 0.9 3.1e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 EF hand DUF2475 PF10629.9 EKX40896.1 - 0.00055 20.1 0.6 0.0018 18.5 0.6 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2475) SAM_Exu PF18609.1 EKX40896.1 - 0.012 15.6 0.3 0.029 14.5 0.3 1.6 1 0 0 1 1 1 0 Exuperantia SAM-like domain Trimer_CC PF08954.11 EKX40896.1 - 0.25 10.9 1.5 0.5 10.0 1.5 1.5 1 0 0 1 1 1 0 Trimerisation motif PDEase_I PF00233.19 EKX40897.1 - 8.2e-64 215.6 4.4 1.5e-63 214.7 4.4 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 EKX40897.1 - 0.022 15.0 0.3 0.097 12.9 0.1 2.2 2 0 0 2 2 2 0 HD domain HR1 PF02185.16 EKX40897.1 - 0.1 12.7 2.3 0.16 12.1 0.5 2.3 2 0 0 2 2 2 0 Hr1 repeat ApoLp-III PF07464.11 EKX40897.1 - 0.46 10.6 4.8 0.88 9.7 1.2 2.4 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF5315 PF17242.2 EKX40898.1 - 0.1 12.5 4.6 5.1 7.0 0.3 2.7 3 0 0 3 3 3 0 Disordered region of unknown function (DUF5315) CLZ PF16526.5 EKX40899.1 - 0.0033 17.7 0.3 0.0059 16.9 0.3 1.4 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Mpv17_PMP22 PF04117.12 EKX40901.1 - 5.1e-14 52.2 3.0 2.4e-13 50.1 1.1 2.4 2 0 0 2 2 2 1 Mpv17 / PMP22 family DUF2475 PF10629.9 EKX40902.1 - 0.018 15.3 0.2 0.051 13.8 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2475) Bac_rhodopsin PF01036.18 EKX40903.1 - 9.5e-14 51.5 7.9 1.6e-13 50.7 7.9 1.3 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein FlxA PF14282.6 EKX40903.1 - 0.072 13.1 0.9 0.1 12.6 0.9 1.2 1 0 0 1 1 1 0 FlxA-like protein Cupin_3 PF05899.12 EKX40904.1 - 4e-18 64.9 0.1 4.2e-18 64.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 EKX40904.1 - 3.2e-06 26.7 0.0 3.7e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EKX40904.1 - 0.013 15.1 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 0 Cupin Cupin_6 PF12852.7 EKX40904.1 - 0.019 14.7 0.0 0.02 14.7 0.0 1.0 1 0 0 1 1 1 0 Cupin EutQ PF06249.12 EKX40904.1 - 0.076 12.8 0.0 0.076 12.8 0.0 1.0 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ DLIC PF05783.11 EKX40905.1 - 2.3e-08 33.3 5.0 7.1e-08 31.7 0.2 2.9 1 1 1 2 2 2 1 Dynein light intermediate chain (DLIC) Roc PF08477.13 EKX40905.1 - 4.4e-08 33.4 0.0 1.2e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EKX40905.1 - 0.00029 20.3 0.1 0.0015 18.0 0.0 2.2 2 1 0 2 2 2 1 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.18 EKX40905.1 - 0.0056 16.1 0.2 0.13 11.6 0.1 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_29 PF13555.6 EKX40905.1 - 0.014 15.2 0.1 0.029 14.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.22 EKX40905.1 - 0.02 14.5 0.0 0.19 11.3 0.0 2.4 2 0 0 2 2 2 0 Ras family AAA_16 PF13191.6 EKX40905.1 - 0.039 14.3 0.1 0.16 12.3 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EKX40905.1 - 0.054 13.8 0.2 0.21 11.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.20 EKX40905.1 - 0.23 10.6 3.1 0.16 11.1 0.2 2.0 2 1 0 2 2 2 0 G-protein alpha subunit PspB PF06667.12 EKX40905.1 - 0.25 11.4 0.9 1.8 8.7 0.0 2.5 2 0 0 2 2 2 0 Phage shock protein B RVT_1 PF00078.27 EKX40906.1 - 1.8e-08 34.2 0.1 3.4e-08 33.3 0.1 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CK2S PF15011.6 EKX40907.1 - 0.06 13.2 0.0 0.069 13.0 0.0 1.1 1 0 0 1 1 1 0 Casein Kinase 2 substrate Methyltransf_PK PF05891.12 EKX40908.1 - 0.18 11.3 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase NMT1 PF09084.11 EKX40909.1 - 1.5e-05 25.0 0.0 2.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EKX40909.1 - 2.3e-05 24.2 0.1 0.0036 17.0 0.0 2.3 2 1 0 2 2 2 2 NMT1-like family Phosphonate-bd PF12974.7 EKX40909.1 - 0.0018 17.9 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Cpn60_TCP1 PF00118.24 EKX40909.1 - 0.032 12.9 0.1 0.045 12.4 0.1 1.1 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family Adaptin_N PF01602.20 EKX40910.1 - 1.8e-141 472.3 10.1 2.5e-141 471.8 10.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EKX40910.1 - 7.4e-66 221.2 1.9 1.8e-64 216.7 0.0 2.9 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EKX40910.1 - 6.3e-17 61.7 3.9 5.7e-09 36.3 0.0 5.7 2 2 4 6 6 6 3 HEAT repeats HEAT PF02985.22 EKX40910.1 - 3e-13 48.8 5.2 0.00098 19.2 0.0 6.2 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 EKX40910.1 - 3.6e-06 27.4 1.9 0.068 13.7 0.0 5.5 5 1 1 6 6 5 2 HEAT-like repeat Cnd3 PF12719.7 EKX40910.1 - 8.3e-06 25.2 4.8 0.00022 20.6 0.3 3.4 3 1 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 EKX40910.1 - 2.9e-05 24.2 2.7 0.43 10.8 0.0 4.7 2 2 2 4 4 4 3 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 EKX40910.1 - 0.00016 21.6 8.1 0.0037 17.3 0.0 5.4 5 1 0 5 5 5 1 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 EKX40910.1 - 0.0015 18.0 1.2 0.0056 16.2 0.0 2.3 2 0 0 2 2 2 1 Armadillo-like CLASP_N PF12348.8 EKX40910.1 - 0.0053 16.3 0.2 1.8 8.1 0.0 3.1 2 1 1 3 3 3 1 CLASP N terminal Keratin_matx PF04579.12 EKX40910.1 - 0.056 13.8 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Keratin, high-sulphur matrix protein DUF5578 PF17741.1 EKX40910.1 - 0.35 10.2 6.6 11 5.3 0.1 4.0 4 1 0 4 4 4 0 Family of unknown function (DUF5578) GYD PF08734.11 EKX40911.1 - 0.17 11.9 0.0 0.45 10.5 0.0 1.7 2 0 0 2 2 2 0 GYD domain P53_tetramer PF07710.11 EKX40913.1 - 0.089 12.1 0.1 1 8.7 0.1 2.5 2 1 0 2 2 2 0 P53 tetramerisation motif Myb_DNA-binding PF00249.31 EKX40914.1 - 4.1e-34 116.5 5.0 1.2e-16 60.6 0.4 2.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX40914.1 - 1.2e-25 89.5 0.4 2.1e-15 56.7 0.1 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EKX40914.1 - 3.3e-05 23.9 0.0 0.071 13.1 0.0 2.2 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EKX40914.1 - 0.0004 20.2 0.0 0.015 15.2 0.0 2.0 1 1 1 2 2 2 1 Myb DNA-binding like MADF_DNA_bdg PF10545.9 EKX40914.1 - 0.00069 19.9 0.3 1.2 9.5 0.1 2.2 1 1 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like SANT_DAMP1_like PF16282.5 EKX40914.1 - 0.0014 18.8 0.1 0.31 11.3 0.1 2.2 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 EKX40914.1 - 0.0031 17.6 0.1 0.31 11.2 0.1 2.1 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Spore_III_AB PF09548.10 EKX40914.1 - 0.025 14.7 0.1 0.029 14.5 0.1 1.3 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Myb_DNA-bind_4 PF13837.6 EKX40914.1 - 0.15 12.5 6.5 6.5 7.2 0.7 3.5 2 2 0 2 2 2 0 Myb/SANT-like DNA-binding domain 2OG-FeII_Oxy_3 PF13640.6 EKX40915.1 - 5.7e-15 56.0 0.2 1.9e-14 54.3 0.2 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EKX40915.1 - 0.0032 17.9 0.3 0.26 11.8 0.1 3.2 2 1 1 3 3 3 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.22 EKX40916.1 - 6.6e-78 262.5 0.0 4.5e-77 259.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_S24 PF00717.23 EKX40917.1 - 7.3e-08 32.3 0.0 1.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EKX40917.1 - 1.8e-06 27.8 0.0 3.7e-05 23.5 0.0 2.1 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 NHL PF01436.21 EKX40917.1 - 0.17 11.9 1.6 0.94 9.6 0.4 2.4 2 0 0 2 2 2 0 NHL repeat Glyco_transf_90 PF05686.12 EKX40918.1 - 4.2e-19 68.7 0.0 4.5e-19 68.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 EKX40918.1 - 9e-06 26.0 0.0 9.7e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Ins_allergen_rp PF06757.13 EKX40918.1 - 0.05 13.6 0.0 0.064 13.2 0.0 1.2 1 0 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification DnaJ PF00226.31 EKX40919.1 - 2.4e-23 82.0 0.1 2.7e-23 81.9 0.1 1.0 1 0 0 1 1 1 1 DnaJ domain Beach PF02138.18 EKX40920.1 - 2.9e-39 135.1 0.0 4.4e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 EKX40920.1 - 3e-16 59.5 7.7 8.3e-05 23.3 0.6 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat Arm PF00514.23 EKX40922.1 - 4.7e-10 39.1 7.7 0.093 12.8 0.1 7.2 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EKX40922.1 - 8.5e-06 26.1 2.7 0.089 13.2 0.1 5.0 3 2 0 4 4 4 1 HEAT repeats DUF913 PF06025.12 EKX40922.1 - 8.1e-05 21.8 0.0 0.00084 18.4 0.0 2.2 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) HEAT_EZ PF13513.6 EKX40922.1 - 0.0027 18.2 6.5 12 6.5 0.1 5.8 5 1 1 6 6 6 1 HEAT-like repeat Laminin_G_3 PF13385.6 EKX40922.1 - 0.05 13.8 0.0 0.85 9.8 0.0 2.2 2 0 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily DUF2524 PF10732.9 EKX40922.1 - 0.068 13.5 2.7 0.27 11.6 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2524) IQ PF00612.27 EKX40923.1 - 0.0031 17.1 1.0 0.013 15.3 1.0 2.1 1 0 0 1 1 1 1 IQ calmodulin-binding motif LRR_6 PF13516.6 EKX40923.1 - 0.12 12.4 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 Leucine Rich repeat DUF1539 PF07560.11 EKX40924.1 - 0.042 13.9 0.1 0.06 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) GtrA PF04138.14 EKX40925.1 - 7.3e-05 23.0 9.0 0.0008 19.6 10.3 1.9 1 1 1 2 2 2 1 GtrA-like protein Asp_Glu_race_2 PF14669.6 EKX40925.1 - 0.13 11.9 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 Putative aspartate racemase E1-E2_ATPase PF00122.20 EKX40926.1 - 2.7e-38 131.3 4.3 4.2e-38 130.7 0.1 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EKX40926.1 - 3.1e-33 115.0 5.9 3.1e-33 115.0 5.9 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EKX40926.1 - 6.3e-17 62.6 3.7 4e-16 59.9 3.7 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EKX40926.1 - 1.7e-16 60.1 0.0 3.7e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EKX40926.1 - 5.1e-12 45.3 0.7 6.8e-11 41.7 0.0 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EKX40926.1 - 3.7e-06 26.9 1.9 0.00025 20.9 1.2 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Guanylate_cyc PF00211.20 EKX40930.1 - 4.2e-26 91.7 0.0 4.8e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain EF-hand_6 PF13405.6 EKX40931.1 - 9.3e-13 47.0 4.2 1.1e-06 28.1 0.1 2.9 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EKX40931.1 - 8.2e-12 43.8 5.4 1.9e-06 27.0 0.2 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX40931.1 - 9.6e-12 45.2 1.4 9.6e-12 45.2 1.4 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 EKX40931.1 - 8e-09 35.2 1.8 0.00022 21.0 0.5 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX40931.1 - 2.6e-07 29.8 7.4 0.00015 21.1 0.5 2.8 3 0 0 3 3 3 2 EF hand FlgD PF03963.14 EKX40931.1 - 0.039 14.3 1.6 0.069 13.5 1.6 1.3 1 0 0 1 1 1 0 Flagellar hook capping protein - N-terminal region SPARC_Ca_bdg PF10591.9 EKX40931.1 - 0.12 12.6 0.5 0.22 11.8 0.5 1.4 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region NBD94 PF16830.5 EKX40933.1 - 0.044 14.2 2.2 0.26 11.7 2.2 2.4 1 0 0 1 1 1 0 Nucleotide-Binding Domain 94 of RH DUF3848 PF12959.7 EKX40933.1 - 0.52 10.4 5.9 1 9.5 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) Adenine_glyco PF03352.13 EKX40933.1 - 2.5 7.9 6.8 0.1 12.3 0.4 2.0 3 0 0 3 3 3 0 Methyladenine glycosylase SpecificRecomb PF10136.9 EKX40933.1 - 6.8 4.9 18.1 0.071 11.4 9.3 2.0 2 0 0 2 2 2 0 Site-specific recombinase Glycos_transf_1 PF00534.20 EKX40937.1 - 0.0013 18.3 0.0 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 TPR_2 PF07719.17 EKX40937.1 - 0.0047 16.9 4.4 0.16 12.2 0.3 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat MRP-S22 PF10245.9 EKX40938.1 - 1.4e-06 28.2 0.0 2.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S22 MRP-L20 PF12824.7 EKX40938.1 - 0.01 16.0 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 Phage_G PF02306.15 EKX40938.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Major spike protein (G protein) FAD-oxidase_C PF02913.19 EKX40939.1 - 1.7e-56 191.6 0.1 3.1e-56 190.8 0.1 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EKX40939.1 - 6.2e-34 116.7 0.0 1.1e-33 116.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Fer4_8 PF13183.6 EKX40939.1 - 1.2e-09 38.5 2.9 3.6e-09 36.9 2.9 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 EKX40939.1 - 8e-09 36.0 3.2 3.2e-08 34.0 3.2 2.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 EKX40939.1 - 2.6e-08 34.3 4.3 7.5e-08 32.8 4.3 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EKX40939.1 - 8.1e-07 29.9 2.9 8.1e-07 29.9 2.9 2.1 2 0 0 2 2 1 1 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 EKX40939.1 - 2.3e-05 24.4 3.8 8.1e-05 22.7 3.9 1.9 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 EKX40939.1 - 5.2e-05 23.3 3.0 0.00015 21.9 3.0 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 EKX40939.1 - 8e-05 22.3 10.7 0.018 14.8 3.8 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 EKX40939.1 - 0.0091 16.0 2.5 0.0091 16.0 2.5 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_4 PF12800.7 EKX40939.1 - 0.023 15.2 3.2 0.023 15.2 3.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_21 PF14697.6 EKX40939.1 - 0.14 12.3 7.1 3.2 8.0 2.1 2.7 1 1 1 2 2 2 0 4Fe-4S dicluster domain HCBP_related PF06594.11 EKX40939.1 - 0.15 12.0 0.0 0.42 10.6 0.0 1.8 1 0 0 1 1 1 0 Haemolysin-type calcium binding protein related domain Fer4_6 PF12837.7 EKX40939.1 - 1.4 9.1 11.0 0.21 11.7 2.6 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_20 PF14691.6 EKX40939.1 - 2.8 7.7 5.3 1 9.2 0.1 2.3 1 1 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster SHOCT PF09851.9 EKX40940.1 - 8.9e-05 22.1 2.4 9.6e-05 22.0 0.3 2.1 2 0 0 2 2 2 1 Short C-terminal domain DUF910 PF06014.11 EKX40940.1 - 0.0066 16.4 0.3 0.014 15.4 0.3 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF910) CRA PF06589.11 EKX40941.1 - 6.5 6.9 5.4 10 6.2 4.9 1.5 1 1 0 1 1 1 0 Circumsporozoite-related antigen (CRA) RNA_pol_3_Rpc31 PF11705.8 EKX40942.1 - 6.4e-05 23.3 2.1 6.4e-05 23.3 2.1 1.8 2 0 0 2 2 1 1 DNA-directed RNA polymerase III subunit Rpc31 EGF_Tenascin PF18720.1 EKX40942.1 - 0.0032 17.5 9.2 0.0074 16.3 9.2 1.6 1 0 0 1 1 1 1 Tenascin EGF domain Nop14 PF04147.12 EKX40942.1 - 0.011 14.0 5.7 0.016 13.4 5.7 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EKX40942.1 - 0.051 11.9 7.0 0.072 11.4 7.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 EKX40942.1 - 0.14 11.9 6.8 0.35 10.6 6.8 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2052 PF09747.9 EKX40942.1 - 0.19 11.9 12.6 0.23 11.6 9.5 2.5 3 0 0 3 3 2 0 Coiled-coil domain containing protein (DUF2052) RXT2_N PF08595.11 EKX40942.1 - 0.21 11.6 5.0 0.49 10.4 5.0 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal RPN2_C PF18004.1 EKX40942.1 - 0.33 10.9 4.5 0.76 9.7 4.5 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PBP1_TM PF14812.6 EKX40942.1 - 0.34 11.3 18.6 1.1 9.6 18.6 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal EGF_2 PF07974.13 EKX40942.1 - 0.46 10.9 15.3 0.1 13.0 11.4 1.9 2 0 0 2 2 2 0 EGF-like domain Cnd2 PF05786.14 EKX40942.1 - 0.72 8.4 6.3 1 8.0 6.3 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 FYDLN_acid PF09538.10 EKX40942.1 - 0.78 10.4 12.6 0.065 13.9 7.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) GCIP PF13324.6 EKX40942.1 - 0.97 9.0 4.4 1.6 8.3 4.4 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Astro_capsid_p PF12226.8 EKX40942.1 - 1.1 8.3 7.4 2 7.5 7.4 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein PPP4R2 PF09184.11 EKX40942.1 - 9.5 5.7 9.8 2.7 7.5 6.7 1.6 2 0 0 2 2 2 0 PPP4R2 Zn_clus PF00172.18 EKX40943.1 - 1.6e-08 34.6 32.0 5.6e-05 23.2 15.4 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain SNF PF00209.18 EKX40944.1 - 3.1e-106 356.1 22.2 6.9e-106 355.0 22.2 1.6 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family Aminotran_1_2 PF00155.21 EKX40945.1 - 5.9e-30 104.7 0.0 2.7e-27 95.9 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class I and II PilS PF08805.11 EKX40945.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 PilS N terminal GATase_5 PF13507.6 EKX40946.1 - 1.5e-103 345.5 0.0 2.4e-103 344.8 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EKX40946.1 - 1.1e-34 119.8 7.0 8.4e-21 74.7 0.2 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 EKX40946.1 - 6.9e-15 55.0 0.0 1.3e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 EKX40946.1 - 6e-11 42.7 0.0 1.9e-10 41.1 0.0 1.9 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain Amidoligase_2 PF12224.8 EKX40947.1 - 0.084 12.5 0.2 0.091 12.4 0.2 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme Caskin-tail PF16632.5 EKX40947.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of Caskin Hva1_TUDOR PF11160.8 EKX40947.1 - 0.14 12.4 0.0 0.17 12.1 0.0 1.1 1 0 0 1 1 1 0 Hypervirulence associated proteins TUDOR domain Scramblase PF03803.15 EKX40948.1 - 9.4e-15 54.5 0.0 1.5e-11 44.1 0.0 2.1 2 0 0 2 2 2 2 Scramblase Roc PF08477.13 EKX40949.1 - 1.1e-11 45.0 0.1 1.7e-05 25.0 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_7 PF13499.6 EKX40949.1 - 3.9e-08 33.6 0.2 1.8e-07 31.5 0.2 2.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX40949.1 - 8.5e-08 31.5 0.3 0.00036 20.2 0.2 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EKX40949.1 - 3.3e-07 29.4 0.1 9.8e-05 21.6 0.1 2.8 2 0 0 2 2 2 1 EF hand Ras PF00071.22 EKX40949.1 - 2e-05 24.3 0.2 0.096 12.3 0.1 2.9 3 0 0 3 3 3 2 Ras family EF-hand_5 PF13202.6 EKX40949.1 - 3e-05 23.3 0.1 0.00027 20.3 0.3 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EKX40949.1 - 0.0047 16.7 0.1 0.017 14.9 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair TIR_2 PF13676.6 EKX40949.1 - 0.013 16.1 0.0 0.05 14.2 0.0 2.0 2 0 0 2 2 2 0 TIR domain HEAT_2 PF13646.6 EKX40949.1 - 0.061 13.7 0.0 0.33 11.4 0.0 2.3 1 0 0 1 1 1 0 HEAT repeats Methyltransf_16 PF10294.9 EKX40950.1 - 4.2e-21 75.4 0.0 6.2e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EKX40950.1 - 1.5e-05 24.6 0.0 2.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EKX40950.1 - 1.6e-05 25.5 0.2 2.5e-05 24.9 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX40950.1 - 0.00041 20.2 0.0 0.00067 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX40950.1 - 0.0031 17.4 0.1 0.0063 16.4 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX40950.1 - 0.0034 18.1 0.0 0.006 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain SOUL PF04832.12 EKX40953.1 - 2.1e-37 128.8 0.0 2.5e-37 128.7 0.0 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein Ion_trans PF00520.31 EKX40954.1 - 1.8e-28 99.4 16.4 2.6e-28 98.9 16.4 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EKX40954.1 - 0.00029 19.6 8.4 0.00058 18.6 8.4 1.5 1 1 0 1 1 1 1 Polycystin cation channel PH PF00169.29 EKX40954.1 - 0.0022 18.5 0.1 0.0051 17.3 0.1 1.7 1 1 0 1 1 1 1 PH domain PDDEXK_6 PF04720.12 EKX40954.1 - 2.4 8.0 4.6 0.54 10.2 1.2 1.5 2 0 0 2 2 2 0 PDDEXK-like family of unknown function LMBR1 PF04791.16 EKX40955.1 - 0.021 13.8 0.3 0.16 10.9 0.3 2.0 1 1 0 1 1 1 0 LMBR1-like membrane protein ATPase PF06745.13 EKX40955.1 - 0.022 14.1 2.3 0.33 10.3 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_25 PF13481.6 EKX40955.1 - 0.037 13.6 0.1 0.18 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EKX40955.1 - 0.044 13.6 10.6 0.053 13.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 EKX40955.1 - 0.048 14.0 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 EKX40955.1 - 0.082 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EKX40955.1 - 0.086 12.6 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.6 EKX40955.1 - 0.092 13.0 0.7 0.34 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sec34 PF04136.15 EKX40955.1 - 0.11 12.4 7.5 0.32 10.9 6.0 2.2 1 1 1 2 2 2 0 Sec34-like family AAA_19 PF13245.6 EKX40955.1 - 0.14 12.4 0.0 0.45 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EKX40955.1 - 0.16 11.7 2.3 1.2 8.8 0.1 2.7 2 0 0 2 2 2 0 AAA domain Spectrin PF00435.21 EKX40955.1 - 0.4 11.2 11.4 1.2 9.6 11.4 1.9 1 0 0 1 1 1 0 Spectrin repeat AAA_28 PF13521.6 EKX40955.1 - 0.47 10.7 2.6 4.1 7.6 0.1 2.9 2 1 0 2 2 2 0 AAA domain DUF1664 PF07889.12 EKX40955.1 - 1.3 9.0 6.3 2.7 8.1 5.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) COG6 PF06419.11 EKX40955.1 - 1.4 7.0 11.0 2.3 6.4 11.0 1.3 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 Acetyltransf_1 PF00583.25 EKX40956.1 - 3.6e-08 33.7 0.0 1.6e-07 31.6 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EKX40956.1 - 4.3e-06 27.1 0.0 8.2e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EKX40956.1 - 0.00047 20.9 0.0 0.0009 19.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EKX40956.1 - 0.0025 17.7 0.0 0.028 14.4 0.0 2.4 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain SDA1 PF05285.12 EKX40956.1 - 1.8 7.9 22.9 3.3 7.1 22.9 1.4 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.12 EKX40956.1 - 3.2 6.1 12.7 5.7 5.3 12.7 1.3 1 0 0 1 1 1 0 Mpp10 protein CwfJ_C_2 PF04676.14 EKX40957.1 - 3.3 8.6 6.2 0.32 11.9 1.2 2.0 2 0 0 2 2 2 0 Protein similar to CwfJ C-terminus 2 Biotin_carb_C PF02785.19 EKX40958.1 - 0.019 15.0 0.0 0.044 13.9 0.0 1.6 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain DUF3883 PF13020.6 EKX40959.1 - 4.1e-06 26.7 0.0 9.3e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) ZZ PF00569.17 EKX40959.1 - 1.3e-05 24.9 5.5 1.6e-05 24.7 4.1 1.9 2 0 0 2 2 2 1 Zinc finger, ZZ type CbeA_antitoxin PF06154.11 EKX40959.1 - 0.09 13.4 0.0 0.97 10.1 0.0 2.7 2 0 0 2 2 2 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A ATP-synt_ab PF00006.25 EKX40961.1 - 2.1e-108 360.9 0.0 3.1e-108 360.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EKX40961.1 - 1.4e-43 147.6 0.0 2.7e-43 146.7 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EKX40961.1 - 1e-14 54.8 2.4 1e-14 54.8 2.4 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.6 EKX40961.1 - 0.053 13.5 0.1 0.51 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF4813 PF16072.5 EKX40962.1 - 0.046 13.4 11.9 0.072 12.7 11.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Mitofilin PF09731.9 EKX40962.1 - 0.13 11.1 4.3 0.18 10.6 4.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein RP-C_C PF11800.8 EKX40963.1 - 7.5 6.6 11.3 6.7 6.8 6.0 2.5 2 0 0 2 2 2 0 Replication protein C C-terminal region EGF_2 PF07974.13 EKX40965.1 - 4.7e-15 55.7 85.6 0.00037 20.8 13.4 5.3 4 1 1 5 5 5 5 EGF-like domain hEGF PF12661.7 EKX40965.1 - 4.4e-05 24.0 55.4 0.0016 19.0 4.7 6.1 5 1 0 5 5 5 4 Human growth factor-like EGF EGF PF00008.27 EKX40965.1 - 9.1e-05 22.7 71.7 0.00062 20.0 8.9 5.6 5 0 0 5 5 5 4 EGF-like domain EGF_Tenascin PF18720.1 EKX40965.1 - 0.011 15.8 8.8 0.011 15.8 8.8 5.3 4 1 1 5 5 5 0 Tenascin EGF domain Laminin_EGF PF00053.24 EKX40965.1 - 0.39 10.9 62.2 1.6 8.9 9.5 5.4 2 2 3 5 5 5 0 Laminin EGF domain RCC1 PF00415.18 EKX40966.1 - 2.8e-91 300.0 23.0 1.2e-15 57.8 0.2 7.0 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX40966.1 - 3.3e-53 176.5 32.1 8.2e-10 38.2 1.3 7.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat DUF3360 PF11840.8 EKX40966.1 - 0.14 10.9 0.2 2.8 6.6 0.0 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3360) Metallophos PF00149.28 EKX40967.1 - 7.6e-25 88.6 0.0 1.2e-24 87.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Cupin_8 PF13621.6 EKX40969.1 - 3.7e-22 79.3 0.3 8.7e-22 78.0 0.3 1.5 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EKX40969.1 - 6.3e-07 29.2 0.0 7.2e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 EKX40969.1 - 0.00048 20.5 0.0 0.00097 19.5 0.0 1.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EKX40969.1 - 0.088 12.5 0.0 0.56 10.0 0.0 2.2 2 0 0 2 2 2 0 Cupin domain bZIP_1 PF00170.21 EKX40970.1 - 9.6e-10 38.4 20.4 1.8e-09 37.6 20.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor ubiquitin PF00240.23 EKX40970.1 - 7.7e-09 35.2 0.1 2.4e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family bZIP_2 PF07716.15 EKX40970.1 - 3.9e-07 30.1 18.3 6.7e-07 29.3 18.3 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EKX40970.1 - 0.00027 21.4 10.1 0.00043 20.7 10.1 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor Rad60-SLD PF11976.8 EKX40970.1 - 0.0004 20.2 0.0 0.0012 18.6 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF3552 PF12072.8 EKX40970.1 - 2.3 7.6 12.1 3.4 7.0 12.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) YabA PF06156.13 EKX40970.1 - 2.7 8.7 11.6 2 9.1 6.7 2.4 1 1 1 2 2 2 0 Initiation control protein YabA GPHR_N PF12537.8 EKX40971.1 - 0.079 13.1 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal CDRT4 PF15213.6 EKX40971.1 - 0.21 12.2 0.8 43 4.7 0.0 3.1 3 0 0 3 3 3 0 CMT1A duplicated region transcript 4 protein LRR_4 PF12799.7 EKX40972.1 - 1.1e-20 73.3 26.1 3.2e-07 30.6 5.7 6.0 3 2 5 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX40972.1 - 3.1e-20 71.7 17.8 2.6e-07 30.3 0.7 6.3 4 2 2 6 6 6 5 Leucine rich repeat LRR_1 PF00560.33 EKX40972.1 - 2.6e-08 33.3 18.6 4.4 8.2 0.6 8.2 7 1 0 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.6 EKX40972.1 - 5e-08 32.4 26.9 0.31 11.2 0.0 9.1 9 1 1 10 10 10 5 Leucine Rich repeat LRR_9 PF14580.6 EKX40972.1 - 0.001 18.6 1.6 0.79 9.2 0.6 2.7 2 1 1 3 3 3 3 Leucine-rich repeat Pkinase PF00069.25 EKX40974.1 - 1.6e-63 214.6 0.0 1.9e-63 214.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX40974.1 - 7.4e-34 117.2 0.0 9.5e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EKX40974.1 - 3.9e-05 22.8 0.1 5.4e-05 22.3 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EKX40974.1 - 7.3e-05 22.2 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EKX40974.1 - 0.00012 21.7 0.1 0.00018 21.1 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EKX40974.1 - 0.0041 16.5 0.0 0.012 14.9 0.0 1.6 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 EKX40974.1 - 0.12 11.9 0.2 0.9 9.1 0.1 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Ank_4 PF13637.6 EKX40975.1 - 0.0035 17.9 0.0 14 6.4 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) EF-hand_1 PF00036.32 EKX40976.1 - 5.2e-07 28.8 0.2 0.004 16.6 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX40976.1 - 1.3e-06 27.8 0.2 0.011 15.7 0.0 2.5 2 1 1 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EKX40976.1 - 8.4e-05 22.9 0.1 0.00012 22.4 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX40976.1 - 0.029 13.9 0.5 0.67 9.6 0.1 2.4 2 1 0 2 2 2 0 EF hand DUF747 PF05346.11 EKX40977.1 - 0.2 11.1 0.1 0.22 10.9 0.1 1.1 1 0 0 1 1 1 0 Eukaryotic membrane protein family ATG16 PF08614.11 EKX40979.1 - 0.0048 17.1 1.3 0.0048 17.1 1.3 2.2 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) DinB_2 PF12867.7 EKX40979.1 - 0.015 15.8 1.1 0.23 11.9 0.1 2.8 2 2 0 2 2 2 0 DinB superfamily Umbravirus_LDM PF04817.12 EKX40979.1 - 0.019 14.3 0.4 0.038 13.4 0.4 1.5 1 0 0 1 1 1 0 Umbravirus long distance movement (LDM) family DUF2203 PF09969.9 EKX40979.1 - 0.025 15.3 9.3 0.93 10.2 1.6 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Sec20 PF03908.13 EKX40979.1 - 0.04 13.8 1.8 0.23 11.4 0.2 2.7 2 0 0 2 2 2 0 Sec20 DUF948 PF06103.11 EKX40979.1 - 0.12 12.7 2.0 1.9 8.8 0.1 2.7 3 1 0 3 3 2 0 Bacterial protein of unknown function (DUF948) Bacillus_HBL PF05791.11 EKX40979.1 - 0.14 12.0 2.4 0.63 9.8 0.1 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) kleA_kleC PF17383.2 EKX40979.1 - 0.33 11.3 4.3 1.1 9.6 0.5 2.9 2 1 1 3 3 3 0 Uncharacterized KorC regulated protein A OmpH PF03938.14 EKX40979.1 - 0.36 11.2 14.2 0.52 10.6 0.5 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) BLOC1_2 PF10046.9 EKX40979.1 - 0.6 10.4 8.5 2.5 8.5 2.0 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.6 EKX40979.1 - 2.3 6.8 9.9 0.4 9.3 0.7 2.1 2 0 0 2 2 2 0 AAA domain Med4 PF10018.9 EKX40979.1 - 3.1 7.4 11.2 3.8 7.1 0.1 3.3 2 1 1 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 TMF_DNA_bd PF12329.8 EKX40979.1 - 3.9 7.5 14.6 7.6 6.6 3.5 3.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PRKG1_interact PF15898.5 EKX40979.1 - 5.5 8.0 19.4 0.19 12.6 3.1 2.9 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Spc7 PF08317.11 EKX40979.1 - 5.5 5.8 19.2 0.33 9.8 2.7 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein CSN5_C PF18323.1 EKX40979.1 - 5.8 7.9 6.4 7.5 7.5 0.1 2.6 2 1 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain DUF724 PF05266.14 EKX40979.1 - 9 6.1 14.1 10 5.9 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF724) ECH_2 PF16113.5 EKX40980.1 - 0.066 12.7 0.6 0.55 9.7 0.0 2.4 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase Hexapep PF00132.24 EKX40981.1 - 6.9e-23 79.5 20.3 1.6e-09 37.1 0.8 4.6 4 1 0 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EKX40981.1 - 0.00011 21.9 11.6 1.6 8.5 0.6 4.6 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase Ion_trans_2 PF07885.16 EKX40983.1 - 4.9e-11 42.4 1.8 4.9e-11 42.4 1.8 1.8 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 EKX40983.1 - 0.00087 18.6 5.5 0.0032 16.7 0.9 2.2 2 0 0 2 2 2 2 Ion transport protein DUF4951 PF16309.5 EKX40983.1 - 0.053 13.6 0.2 0.16 12.0 0.1 1.8 2 0 0 2 2 2 0 Domian of unknown function (DUF4951) DUF5362 PF17319.2 EKX40983.1 - 0.079 12.8 1.9 0.33 10.8 0.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5362) Kinase-PPPase PF03618.14 EKX40984.1 - 5.3e-58 196.8 0.0 5.8e-58 196.7 0.0 1.0 1 0 0 1 1 1 1 Kinase/pyrophosphorylase GHL6 PF14871.6 EKX40984.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 PAS_9 PF13426.7 EKX40985.1 - 9.2e-16 58.0 0.0 1e-15 57.9 0.0 1.0 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 EKX40985.1 - 6e-09 36.1 0.0 6.4e-09 36.0 0.0 1.0 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EKX40985.1 - 2.8e-08 33.7 0.0 3e-08 33.6 0.0 1.0 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EKX40985.1 - 0.008 16.4 0.0 0.01 16.1 0.0 1.1 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.6 EKX40985.1 - 0.12 12.5 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 PAS domain PAS_9 PF13426.7 EKX40986.1 - 3.5e-16 59.4 0.0 4e-16 59.2 0.0 1.0 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 EKX40986.1 - 9.8e-10 38.6 0.0 1.1e-09 38.5 0.0 1.0 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EKX40986.1 - 1.5e-07 31.4 0.0 1.8e-07 31.2 0.0 1.0 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EKX40986.1 - 1.1e-05 25.6 0.0 1.2e-05 25.5 0.0 1.0 1 0 0 1 1 1 1 PAS fold LodA_N PF17990.1 EKX40988.1 - 0.026 14.5 0.3 0.027 14.4 0.3 1.0 1 0 0 1 1 1 0 L-Lysine epsilon oxidase N-terminal Abhydrolase_6 PF12697.7 EKX40989.1 - 3.3e-14 54.0 3.9 1.3e-13 52.1 3.9 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EKX40989.1 - 8.8e-13 48.5 0.1 1.9e-11 44.1 0.1 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EKX40989.1 - 9.3e-08 31.6 0.0 1.3e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EKX40989.1 - 0.00025 21.2 0.0 0.00034 20.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PAF-AH_p_II PF03403.13 EKX40989.1 - 0.002 16.7 0.0 0.003 16.1 0.0 1.2 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydro_lipase PF04083.16 EKX40989.1 - 0.0096 15.5 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region PGAP1 PF07819.13 EKX40989.1 - 0.017 14.9 0.0 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 PGAP1-like protein DHHC PF01529.20 EKX40990.1 - 1.1e-28 100.0 6.9 1.1e-28 100.0 6.9 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase HiaBD2 PF15403.6 EKX40990.1 - 0.2 12.1 0.0 0.39 11.1 0.0 1.4 1 0 0 1 1 1 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) TIG PF01833.24 EKX40991.1 - 1.3e-16 60.4 14.6 1e-08 35.1 1.2 5.1 5 0 0 5 5 5 2 IPT/TIG domain zf-C3HC4_3 PF13920.6 EKX40991.1 - 1.8e-12 46.9 4.0 1.2e-11 44.3 4.0 2.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Kelch_4 PF13418.6 EKX40991.1 - 2.2e-08 34.0 4.6 0.093 12.8 0.1 4.9 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EKX40991.1 - 9.3e-05 22.3 9.0 0.076 13.0 0.0 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 EKX40991.1 - 0.0005 19.6 6.5 0.23 11.1 0.5 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 EKX40991.1 - 0.044 14.1 14.5 2.7 8.4 0.0 6.2 6 0 0 6 6 6 0 Kelch motif Kelch_2 PF07646.15 EKX40991.1 - 0.14 12.1 10.7 1.5 8.9 0.5 4.8 5 0 0 5 5 5 0 Kelch motif RMMBL PF07521.12 EKX40991.1 - 0.22 11.5 0.0 0.45 10.5 0.0 1.4 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain FdhE PF04216.12 EKX40991.1 - 1.2 9.0 5.3 2 8.3 5.3 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Cnd1_N PF12922.7 EKX40992.1 - 0.076 12.9 0.2 0.096 12.5 0.2 1.1 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term Oxysterol_BP PF01237.18 EKX40994.1 - 5.1e-39 134.2 1.8 6.6e-27 94.3 0.0 2.2 1 1 1 2 2 2 2 Oxysterol-binding protein DUF333 PF03891.15 EKX40994.1 - 0.073 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF333) Baculo_PEP_C PF04513.12 EKX40995.1 - 0.45 10.5 8.8 1.2 9.2 1.8 3.6 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus IZUMO PF15005.6 EKX40995.1 - 2 8.9 7.4 1.6 9.2 4.7 2.3 1 1 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated Paramecium_SA PF01508.16 EKX40997.1 - 0.00028 21.2 11.4 0.63 10.5 11.4 2.7 1 1 0 1 1 1 1 Paramecium surface antigen domain Ank_4 PF13637.6 EKX40998.1 - 7.4e-22 77.4 9.2 3e-07 30.8 0.1 3.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX40998.1 - 3.9e-20 71.6 2.1 3.6e-09 36.7 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX40998.1 - 2.9e-18 66.2 2.1 8e-09 36.0 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX40998.1 - 1.5e-17 61.9 1.3 0.0019 18.5 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 EKX40998.1 - 1.6e-13 50.4 7.3 0.0049 17.3 0.1 4.2 4 0 0 4 4 4 4 Ankyrin repeat Glyco_hydro_47 PF01532.20 EKX40999.1 - 2.6e-101 339.8 0.0 3.6e-101 339.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 EKX40999.1 - 0.2 10.1 0.0 0.6 8.5 0.0 1.8 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Kin17_mid PF10357.9 EKX41000.1 - 1.1e-40 138.4 1.2 1.1e-40 138.4 1.2 2.3 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 EKX41000.1 - 1.9e-22 79.1 5.3 9.1e-21 73.7 3.0 2.5 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain KOW PF00467.29 EKX41000.1 - 0.0065 16.4 0.5 0.0065 16.4 0.5 3.4 3 1 0 3 3 3 1 KOW motif zf-met PF12874.7 EKX41000.1 - 0.011 16.1 5.6 0.024 15.0 5.6 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DPM3 PF08285.11 EKX41000.1 - 0.038 14.2 1.1 0.074 13.3 1.1 1.4 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) zf-C2H2_jaz PF12171.8 EKX41000.1 - 0.072 13.4 3.6 0.2 12.0 3.6 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Thioredoxin_15 PF18403.1 EKX41000.1 - 0.085 12.8 2.3 1.7 8.5 0.3 2.3 2 0 0 2 2 2 0 Thioredoxin-like domain MAS20 PF02064.15 EKX41000.1 - 3.3 7.8 10.2 4.4 7.4 1.1 2.6 3 0 0 3 3 3 0 MAS20 protein import receptor DUF1677 PF07911.13 EKX41000.1 - 5.4 7.5 7.4 3.9 7.9 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1677) ANAPC3 PF12895.7 EKX41001.1 - 0.074 13.3 0.2 0.44 10.8 0.2 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EKX41001.1 - 0.1 12.7 1.3 36 4.7 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Calcipressin PF04847.12 EKX41001.1 - 0.24 11.1 0.3 0.46 10.2 0.3 1.4 1 0 0 1 1 1 0 Calcipressin WD40 PF00400.32 EKX41002.1 - 1.1e-06 29.3 14.6 0.00027 21.7 0.2 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Kelch_6 PF13964.6 EKX41002.1 - 0.05 13.9 0.2 2.6 8.5 0.3 2.9 2 0 0 2 2 2 0 Kelch motif HAD_2 PF13419.6 EKX41003.1 - 7.5e-15 55.5 0.0 1.1e-14 54.9 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EKX41003.1 - 2.4e-11 44.3 0.2 8e-11 42.6 0.2 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EKX41003.1 - 6.4e-06 26.1 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EKX41003.1 - 3e-05 24.5 0.0 4.1e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.18 EKX41003.1 - 0.005 16.6 0.0 0.0084 15.9 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase TPR_2 PF07719.17 EKX41004.1 - 0.085 13.0 0.2 1.9 8.8 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat FIBP PF05427.11 EKX41005.1 - 5.8e-45 154.1 6.7 4.9e-33 114.9 1.7 2.3 2 0 0 2 2 2 2 Acidic fibroblast growth factor binding (FIBP) DUF3464 PF11947.8 EKX41005.1 - 0.0061 16.3 0.3 0.012 15.3 0.3 1.4 1 0 0 1 1 1 1 Photosynthesis affected mutant 68 DDHD PF02862.17 EKX41005.1 - 0.0098 16.1 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 DDHD domain Orf78 PF06024.12 EKX41005.1 - 0.027 14.8 0.1 0.079 13.3 0.1 1.7 1 0 0 1 1 1 0 Orf78 (ac78) Connexin PF00029.19 EKX41005.1 - 0.03 14.1 1.1 0.057 13.2 1.1 1.4 1 0 0 1 1 1 0 Connexin EMC3_TMCO1 PF01956.16 EKX41005.1 - 0.37 10.5 7.0 2.8 7.7 3.1 2.7 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like CLN3 PF02487.17 EKX41005.1 - 0.4 9.7 3.4 0.49 9.4 1.0 2.1 2 0 0 2 2 2 0 CLN3 protein DUF3584 PF12128.8 EKX41005.1 - 0.54 7.7 14.8 1.7 6.1 15.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Afi1 PF07792.12 EKX41005.1 - 1.6 9.2 6.9 3.7 8.0 6.9 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Folliculin PF11704.8 EKX41005.1 - 3 7.7 5.9 7.7 6.4 5.9 1.6 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport ALMT PF11744.8 EKX41005.1 - 5.1 5.8 11.9 1.2 7.9 8.6 1.5 2 0 0 2 2 2 0 Aluminium activated malate transporter Coilin_N PF15862.5 EKX41005.1 - 6.4 6.6 14.3 18 5.1 14.3 1.7 1 0 0 1 1 1 0 Coilin N-terminus DUF3807 PF12720.7 EKX41005.1 - 7.2 6.8 15.1 15 5.8 15.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Presenilin PF01080.17 EKX41005.1 - 8.4 5.0 9.3 15 4.2 9.3 1.3 1 0 0 1 1 1 0 Presenilin RVT_1 PF00078.27 EKX41006.1 - 2.6e-05 23.9 0.0 4.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ORC5_C PF14630.6 EKX41006.1 - 0.086 12.3 9.2 0.06 12.8 7.0 1.7 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 5 C-terminus Sgf11 PF08209.11 EKX41007.1 - 0.023 14.2 9.7 0.64 9.6 0.5 3.0 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) TfoX_C PF04994.13 EKX41007.1 - 0.12 12.5 0.0 22 5.2 0.0 2.5 2 0 0 2 2 2 0 TfoX C-terminal domain Radical_SAM PF04055.21 EKX41007.1 - 0.18 12.2 0.1 4.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Radical SAM superfamily ADH_zinc_N PF00107.26 EKX41007.1 - 0.22 11.5 0.0 14 5.7 0.0 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase NqrM PF04400.13 EKX41007.1 - 3.6 7.4 10.9 7.6 6.4 1.5 2.4 2 0 0 2 2 2 0 (Na+)-NQR maturation NqrM DUF1218 PF06749.12 EKX41008.1 - 3 8.4 8.7 8.9 6.9 0.7 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) DSPn PF14671.6 EKX41010.1 - 2.1e-39 135.2 0.0 3.5e-39 134.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EKX41010.1 - 2.2e-14 53.4 0.0 1.4e-13 50.8 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX41010.1 - 0.00016 21.4 0.0 0.00039 20.1 0.0 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX41010.1 - 0.00054 20.1 0.0 0.00093 19.3 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EKX41010.1 - 0.0026 17.8 0.0 0.0039 17.2 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Peroxin-13_N PF04088.13 EKX41011.1 - 0.33 11.2 2.9 0.94 9.7 0.1 3.2 2 0 0 2 2 2 0 Peroxin 13, N-terminal region tRNA-synt_1c PF00749.21 EKX41014.1 - 2.2e-69 233.8 0.0 1.4e-34 119.5 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain PUB PF09409.10 EKX41015.1 - 1.7e-12 47.1 0.0 3.2e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 PUB domain Mog1 PF04603.12 EKX41015.1 - 0.14 12.6 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 Ran-interacting Mog1 protein LdpA_C PF12617.8 EKX41016.1 - 8.7e-39 133.0 0.0 1.2e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 Iron-Sulfur binding protein C terminal Fer4_6 PF12837.7 EKX41016.1 - 5.9e-05 23.0 18.2 0.0027 17.7 3.9 2.9 3 0 0 3 3 3 2 4Fe-4S binding domain DUF561 PF04481.12 EKX41016.1 - 6.6e-05 22.2 0.0 0.0001 21.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF561) Fer4_10 PF13237.6 EKX41016.1 - 0.00047 20.2 0.9 0.00047 20.2 0.9 2.5 2 1 1 3 3 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 EKX41016.1 - 0.00051 20.6 8.9 0.0085 16.7 0.3 2.6 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 EKX41016.1 - 0.00079 19.1 1.4 0.00079 19.1 1.4 3.3 4 0 0 4 4 4 1 4Fe-4S binding domain Fer4_2 PF12797.7 EKX41016.1 - 0.0041 17.1 1.8 0.0041 17.1 1.8 2.8 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_16 PF13484.6 EKX41016.1 - 0.0066 17.4 0.3 0.0066 17.4 0.3 2.5 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 EKX41016.1 - 0.0079 16.6 0.2 0.0079 16.6 0.2 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 EKX41016.1 - 0.036 14.2 1.6 0.036 14.2 1.6 2.8 2 1 2 4 4 4 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 EKX41016.1 - 0.047 14.2 1.3 0.047 14.2 1.3 3.0 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_22 PF17179.4 EKX41016.1 - 0.21 12.5 5.7 0.18 12.7 4.2 1.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 EKX41016.1 - 1.8 8.8 13.1 0.95 9.6 9.7 2.3 2 1 0 2 2 2 0 4Fe-4S dicluster domain Pkinase PF00069.25 EKX41018.1 - 9.5e-45 153.0 0.2 5.4e-38 130.9 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EKX41018.1 - 5.4e-15 55.4 1.2 1e-13 51.2 0.2 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EKX41018.1 - 0.0009 19.2 0.0 0.0016 18.4 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EKX41018.1 - 0.008 15.8 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase IL2 PF00715.17 EKX41018.1 - 0.016 15.1 0.1 0.078 12.9 0.0 2.1 2 0 0 2 2 2 0 Interleukin 2 UQ_con PF00179.26 EKX41019.1 - 3e-53 179.2 0.0 3.3e-53 179.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EKX41019.1 - 0.0048 16.6 0.0 0.006 16.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EKX41019.1 - 0.02 15.1 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 EKX41019.1 - 0.077 12.9 0.1 0.13 12.2 0.1 1.4 1 1 0 1 1 1 0 UEV domain LRR_6 PF13516.6 EKX41020.1 - 3.5e-08 32.9 29.0 0.06 13.4 0.1 7.8 6 2 1 7 7 7 5 Leucine Rich repeat LRR_4 PF12799.7 EKX41020.1 - 3.6e-08 33.6 21.4 0.28 11.7 0.4 5.1 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX41020.1 - 1.5e-06 27.9 20.2 0.00052 19.7 2.1 5.2 3 2 1 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 EKX41020.1 - 0.0013 19.0 14.4 21 6.2 0.1 6.3 5 1 0 5 5 5 2 Leucine Rich Repeat Metallophos PF00149.28 EKX41021.1 - 3.2e-12 47.4 0.0 4.9e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4200 PF13863.6 EKX41023.1 - 0.0003 21.2 8.8 0.0003 21.2 8.8 4.8 1 1 3 4 4 4 2 Domain of unknown function (DUF4200) DUF2968 PF11180.8 EKX41023.1 - 0.0056 16.3 18.7 0.0056 16.3 18.7 4.0 2 1 2 4 4 4 2 Protein of unknown function (DUF2968) Spc42p PF11544.8 EKX41023.1 - 0.015 15.3 4.1 0.015 15.3 4.1 4.4 2 1 1 4 4 4 0 Spindle pole body component Spc42p Ammonium_transp PF00909.21 EKX41024.1 - 2.3e-108 362.5 27.5 2.6e-108 362.3 27.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Ammonium_transp PF00909.21 EKX41025.1 - 2.1e-112 375.7 27.9 2.7e-112 375.4 27.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family PspB PF06667.12 EKX41025.1 - 1.2 9.3 7.2 0.95 9.6 0.1 3.7 3 1 1 4 4 4 0 Phage shock protein B DUF2104 PF09877.9 EKX41025.1 - 10 6.5 8.9 2.3 8.6 0.1 3.6 2 1 0 3 3 3 0 Predicted membrane protein (DUF2104) Ammonium_transp PF00909.21 EKX41026.1 - 2e-82 277.0 11.8 5.1e-82 275.7 11.8 1.6 1 1 0 1 1 1 1 Ammonium Transporter Family Tom22 PF04281.13 EKX41026.1 - 0.026 14.3 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 ABC_tran_CTD PF16326.5 EKX41026.1 - 0.32 11.3 3.2 0.8 10.0 3.2 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain Collagen PF01391.18 EKX41027.1 - 5.8e-18 64.4 68.9 1.7e-09 37.3 28.9 3.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) DUF4709 PF15821.5 EKX41027.1 - 0.055 13.8 0.2 0.082 13.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4709) PA PF02225.22 EKX41027.1 - 0.11 12.5 0.2 0.78 9.8 0.0 2.4 2 0 0 2 2 2 0 PA domain E1-E2_ATPase PF00122.20 EKX41028.1 - 4e-47 160.1 6.9 1.3e-45 155.1 2.0 3.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EKX41028.1 - 3.6e-17 63.4 0.0 1.4e-16 61.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EKX41028.1 - 2e-13 49.8 0.0 5.7e-13 48.3 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EKX41028.1 - 0.00056 19.7 0.0 0.0025 17.6 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EKX41028.1 - 0.027 14.6 0.0 0.09 12.9 0.0 1.9 2 0 0 2 2 2 0 Cation transport ATPase (P-type) Peptidase_M56 PF05569.11 EKX41028.1 - 0.032 13.4 0.6 0.25 10.5 0.0 2.2 2 0 0 2 2 2 0 BlaR1 peptidase M56 SafA PF17073.5 EKX41028.1 - 0.86 9.6 3.7 2.9 7.9 3.7 1.9 1 0 0 1 1 1 0 Two-component-system connector protein DnaJ PF00226.31 EKX41030.1 - 2e-17 63.0 0.1 6e-16 58.3 0.1 2.1 1 1 0 1 1 1 1 DnaJ domain EF-hand_1 PF00036.32 EKX41031.1 - 9e-11 40.5 3.5 5.3e-05 22.5 0.8 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EKX41031.1 - 4.7e-09 36.6 0.1 3e-07 30.8 0.2 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX41031.1 - 1.9e-08 33.6 1.4 0.0064 16.3 0.2 3.5 3 0 0 3 3 3 2 EF-hand domain PDZ PF00595.24 EKX41031.1 - 4.8e-07 30.0 0.1 1.1e-06 28.8 0.1 1.6 1 0 0 1 1 1 1 PDZ domain EF-hand_8 PF13833.6 EKX41031.1 - 1.6e-06 27.8 1.2 0.0021 17.9 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair PDZ_6 PF17820.1 EKX41031.1 - 3.8e-06 26.7 0.3 8.3e-06 25.6 0.3 1.6 1 0 0 1 1 1 1 PDZ domain EF-hand_5 PF13202.6 EKX41031.1 - 0.0014 18.1 1.9 0.054 13.0 0.1 2.4 2 0 0 2 2 2 1 EF hand PDZ_2 PF13180.6 EKX41031.1 - 0.0053 17.0 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX41031.1 - 0.14 12.1 0.2 0.59 10.1 0.2 2.0 1 1 0 1 1 1 0 Tricorn protease PDZ domain CDC45 PF02724.14 EKX41031.1 - 0.41 8.9 4.2 0.54 8.5 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 EKX41032.1 - 0.07 13.6 1.4 0.12 12.7 1.4 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 TRAP_alpha PF03896.16 EKX41032.1 - 0.1 11.8 7.1 0.15 11.2 7.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.12 EKX41032.1 - 0.12 10.6 21.2 0.16 10.2 21.2 1.1 1 0 0 1 1 1 0 Nop14-like family V_ATPase_I PF01496.19 EKX41032.1 - 0.12 10.3 0.2 0.17 9.8 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4295 PF14128.6 EKX41032.1 - 0.15 11.9 0.1 0.68 9.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4295) RRN3 PF05327.11 EKX41032.1 - 0.16 10.4 9.1 0.21 10.1 9.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC27 PF09507.10 EKX41032.1 - 1.8 7.9 16.4 2.6 7.3 16.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.14 EKX41032.1 - 2.6 6.2 14.8 3.6 5.8 14.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 EKX41032.1 - 2.8 5.9 27.3 4.6 5.2 27.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF2151 PF10221.9 EKX41032.1 - 3.9 5.9 5.7 6 5.3 5.7 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator SDA1 PF05285.12 EKX41032.1 - 4.2 6.7 20.4 5.9 6.2 20.4 1.2 1 0 0 1 1 1 0 SDA1 DUF2722 PF10846.8 EKX41032.1 - 4.5 6.1 8.4 7.5 5.4 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RXT2_N PF08595.11 EKX41032.1 - 6 6.9 11.9 13 5.8 11.9 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Cytomega_UL84 PF06284.11 EKX41032.1 - 7.1 5.0 6.2 11 4.3 6.2 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein TFIIF_alpha PF05793.12 EKX41032.1 - 8 4.9 23.7 12 4.4 23.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Homeobox_KN PF05920.11 EKX41033.1 - 1.3e-13 50.6 0.2 2.4e-13 49.8 0.2 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EKX41033.1 - 2.8e-07 30.3 0.6 4.6e-07 29.6 0.6 1.4 1 0 0 1 1 1 1 Homeodomain HTH_3 PF01381.22 EKX41033.1 - 0.024 14.7 0.0 0.063 13.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix VPS9 PF02204.18 EKX41035.1 - 1.5e-29 102.2 1.2 2.3e-29 101.6 0.5 1.6 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EKX41035.1 - 0.0029 17.9 0.0 0.0056 17.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) SelB-wing_2 PF09106.11 EKX41035.1 - 0.13 12.5 0.3 0.13 12.5 0.3 1.7 2 0 0 2 2 2 0 Elongation factor SelB, winged helix Pirin PF02678.16 EKX41036.1 - 1.3e-23 83.0 0.0 2.9e-23 81.9 0.0 1.7 1 1 0 1 1 1 1 Pirin Pirin_C PF05726.13 EKX41036.1 - 8.2e-18 64.7 0.1 2.7e-16 59.8 0.1 2.5 1 1 0 1 1 1 1 Pirin C-terminal cupin domain RWP-RK PF02042.15 EKX41038.1 - 8.8e-14 51.2 0.2 1.3e-13 50.6 0.2 1.2 1 0 0 1 1 1 1 RWP-RK domain Bestrophin PF01062.21 EKX41039.1 - 1.3e-35 123.2 0.3 1.5e-35 123.0 0.3 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel SMC_hinge PF06470.13 EKX41040.1 - 0.074 13.4 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain DUF19 PF01579.18 EKX41040.1 - 0.15 11.9 3.8 0.53 10.1 0.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF19) AAA_23 PF13476.6 EKX41040.1 - 1.9 9.0 11.4 0.22 12.0 3.1 2.2 2 0 0 2 2 2 0 AAA domain Spc24 PF08286.11 EKX41040.1 - 2.5 8.4 6.9 4.1 7.7 4.8 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 GST_C_2 PF13410.6 EKX41042.1 - 0.0019 18.2 0.0 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EKX41042.1 - 0.0095 16.1 0.7 0.021 15.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EKX41042.1 - 0.022 15.1 0.0 0.053 13.9 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EKX41042.1 - 0.042 14.1 2.0 0.071 13.3 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Ank_2 PF12796.7 EKX41044.1 - 2.6e-30 104.9 0.3 1.5e-16 60.7 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX41044.1 - 5.6e-29 100.1 0.1 7.9e-09 35.9 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EKX41044.1 - 2.7e-27 94.0 1.5 5.5e-08 32.9 0.2 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EKX41044.1 - 2e-24 85.3 0.5 1.8e-08 34.5 0.0 3.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX41044.1 - 4.3e-21 72.7 0.3 0.00024 21.3 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat ArlS_N PF18719.1 EKX41044.1 - 0.24 11.6 0.0 12 6.1 0.0 2.3 2 0 0 2 2 2 0 ArlS sensor domain zf-GRF PF06839.12 EKX41045.1 - 1.3e-11 44.4 5.5 3.1e-11 43.2 5.5 1.7 1 0 0 1 1 1 1 GRF zinc finger Beta_helix PF13229.6 EKX41045.1 - 3.5e-08 33.4 2.7 8.7e-08 32.2 1.9 1.9 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 EKX41045.1 - 0.0078 15.5 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.7 EKX41045.1 - 0.077 12.8 0.3 0.13 12.0 0.3 1.4 1 0 0 1 1 1 0 Pectate lyase superfamily protein DegS PF05384.11 EKX41047.1 - 0.012 15.1 0.9 0.019 14.4 0.9 1.3 1 0 0 1 1 1 0 Sensor protein DegS PBP_GOBP PF01395.22 EKX41048.1 - 0.026 14.7 0.3 0.026 14.7 0.3 1.6 2 0 0 2 2 2 0 PBP/GOBP family GIDA PF01134.22 EKX41049.1 - 1.2e-148 495.4 0.0 1.5e-148 495.1 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 EKX41049.1 - 2.4e-62 210.8 0.0 3.4e-62 210.4 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 EKX41049.1 - 1.1e-06 28.3 1.0 1.9e-06 27.5 1.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EKX41049.1 - 9.8e-06 25.0 0.2 3.8e-05 23.1 0.3 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EKX41049.1 - 7.9e-05 21.9 7.3 0.00013 21.2 1.7 2.5 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.27 EKX41049.1 - 0.00026 21.5 0.2 0.00089 19.8 0.2 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EKX41049.1 - 0.0013 18.0 0.4 0.0041 16.5 0.2 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EKX41049.1 - 0.0033 16.2 0.3 0.014 14.1 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 EKX41049.1 - 0.078 12.5 2.6 0.31 10.6 0.8 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EKX41049.1 - 0.084 13.1 0.8 0.22 11.8 0.8 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EKX41049.1 - 0.1 11.8 0.2 0.59 9.3 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 EKX41049.1 - 0.1 11.6 0.8 0.19 10.7 0.8 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EKX41049.1 - 0.11 11.7 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EKX41049.1 - 0.14 11.4 0.3 0.21 10.8 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 EKX41049.1 - 0.21 10.4 0.4 3.5 6.4 0.3 2.1 2 0 0 2 2 2 0 Tryptophan halogenase TIG PF01833.24 EKX41050.1 - 1.1e-29 102.3 26.8 1.3e-07 31.6 0.5 6.1 6 0 0 6 6 6 5 IPT/TIG domain Pkinase PF00069.25 EKX41051.1 - 8.3e-58 195.8 0.0 1.2e-57 195.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX41051.1 - 2e-40 138.7 0.0 3.4e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX41051.1 - 2e-06 27.3 0.0 6.9e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EKX41051.1 - 0.00097 18.3 0.1 0.0018 17.4 0.1 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 EKX41051.1 - 0.0023 16.8 0.0 0.0032 16.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EKX41051.1 - 0.04 13.5 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EKX41051.1 - 0.25 11.2 0.0 0.48 10.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PDZ PF00595.24 EKX41052.1 - 1.4e-07 31.7 0.4 0.00012 22.3 0.0 2.5 2 1 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX41052.1 - 1.6e-06 28.3 0.1 0.027 14.8 0.1 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EKX41052.1 - 2e-05 24.3 1.4 0.17 11.8 0.1 3.2 2 2 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 EKX41052.1 - 3.9e-05 23.5 0.4 0.23 11.4 0.0 3.6 2 1 0 2 2 2 2 Tricorn protease PDZ domain HlyD PF00529.20 EKX41052.1 - 0.098 12.5 0.0 0.51 10.3 0.0 2.0 2 0 0 2 2 2 0 HlyD membrane-fusion protein of T1SS Malt_amylase_C PF16657.5 EKX41052.1 - 0.21 11.8 0.6 0.47 10.6 0.2 1.8 2 0 0 2 2 2 0 Maltogenic Amylase, C-terminal domain C2 PF00168.30 EKX41053.1 - 1.2e-73 244.0 0.2 5e-20 71.7 0.0 7.9 8 0 0 8 8 8 6 C2 domain Terminase_3C PF17288.2 EKX41054.1 - 0.077 13.4 0.9 5.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Terminase RNAseH like domain DUF1835 PF08874.10 EKX41055.1 - 0.026 14.7 0.4 0.13 12.5 0.0 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1835) Peptidase_C14 PF00656.22 EKX41056.1 - 0.0039 17.2 0.0 0.0088 16.0 0.0 1.4 1 1 0 1 1 1 1 Caspase domain DUF3136 PF11334.8 EKX41057.1 - 0.079 12.8 0.2 17 5.3 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3136) TPR_12 PF13424.6 EKX41060.1 - 2.3e-76 252.1 11.0 5.3e-17 61.9 0.7 4.4 1 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 EKX41060.1 - 1.1e-53 177.7 0.4 1.1e-09 37.8 0.0 6.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 EKX41060.1 - 3.1e-38 128.1 6.0 2e-07 30.5 0.0 7.1 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.17 EKX41060.1 - 1.5e-29 99.7 7.7 0.00046 20.1 0.0 7.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 EKX41060.1 - 2e-26 90.0 3.4 0.00038 20.3 0.0 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 EKX41060.1 - 7.8e-19 67.1 6.7 0.0016 18.1 0.0 6.7 8 0 0 8 8 8 5 TPR repeat TPR_8 PF13181.6 EKX41060.1 - 6.8e-18 63.3 8.5 0.0097 16.0 0.0 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 EKX41060.1 - 4.8e-17 61.2 1.3 0.019 15.7 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX41060.1 - 2.7e-16 59.9 4.0 0.00031 21.3 2.0 5.8 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX41060.1 - 9.3e-14 51.5 2.2 4.5e-10 39.4 0.6 2.0 1 1 2 3 3 3 2 MalT-like TPR region MIT PF04212.18 EKX41060.1 - 1.1e-11 44.7 10.4 0.0012 18.9 0.1 6.8 4 3 3 7 7 7 2 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 EKX41060.1 - 3.4e-08 33.4 0.8 0.62 10.9 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat PPR PF01535.20 EKX41060.1 - 3.8e-07 29.9 0.8 2.3 8.6 0.0 5.1 6 0 0 6 6 5 2 PPR repeat SHNi-TPR PF10516.9 EKX41060.1 - 6e-07 28.8 0.5 1.9 8.0 0.0 5.7 6 0 0 6 6 6 1 SHNi-TPR RPN7 PF10602.9 EKX41060.1 - 1.1e-06 28.5 3.8 1.1 9.0 0.0 5.5 1 1 5 6 6 6 1 26S proteasome subunit RPN7 TPR_6 PF13174.6 EKX41060.1 - 6.4e-06 26.5 8.5 6.5 7.6 0.1 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat DUF5113 PF17140.4 EKX41060.1 - 1.9e-05 24.6 2.6 1.5 8.6 0.3 5.1 5 1 0 5 5 5 1 Domain of unknown function (DUF5113) ANAPC3 PF12895.7 EKX41060.1 - 3.9e-05 23.8 4.3 0.016 15.4 0.3 5.1 2 2 3 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 EKX41060.1 - 4.7e-05 23.2 2.6 6.3 6.4 0.0 5.2 1 1 4 5 5 5 1 Tetratricopeptide repeat-like domain TPR_19 PF14559.6 EKX41060.1 - 6.7e-05 23.3 7.6 0.53 10.8 0.2 5.3 3 1 3 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX41060.1 - 0.00041 20.5 1.1 2.2 8.9 0.0 4.9 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_3 PF07720.12 EKX41060.1 - 0.00054 19.9 1.6 3.1 7.9 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX41060.1 - 0.00062 19.9 3.3 0.05 13.7 0.2 3.4 4 1 0 4 4 3 1 Tetratricopeptide repeat PPR_2 PF13041.6 EKX41060.1 - 0.0058 16.8 2.6 8.3 6.7 0.0 4.3 5 0 0 5 5 4 0 PPR repeat family TPR_5 PF12688.7 EKX41060.1 - 0.0087 16.3 2.7 3.7 7.8 0.1 3.4 2 2 2 4 4 4 1 Tetratrico peptide repeat TetR_C_19 PF17924.1 EKX41060.1 - 0.01 16.4 0.3 60 4.3 0.0 3.9 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain BTAD PF03704.17 EKX41060.1 - 0.26 11.7 4.8 7.6 7.0 2.2 4.1 3 1 0 3 3 2 0 Bacterial transcriptional activator domain Spore_coat_CotO PF14153.6 EKX41062.1 - 0.028 14.4 4.0 0.047 13.6 4.0 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Connexin PF00029.19 EKX41062.1 - 1.1 9.0 5.3 0.98 9.1 4.0 1.6 2 0 0 2 2 2 0 Connexin RPOL_N PF14700.6 EKX41062.1 - 8.4 5.7 10.6 18 4.6 10.6 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal DUF1995 PF09353.10 EKX41063.1 - 3.3e-18 66.5 0.0 8.1e-18 65.2 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1995) BAH PF01426.18 EKX41064.1 - 2.7e-10 40.2 0.2 5.3e-10 39.2 0.2 1.5 1 0 0 1 1 1 1 BAH domain Pox_Ag35 PF03286.14 EKX41064.1 - 0.7 9.7 12.3 0.72 9.6 7.5 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein ELM2 PF01448.24 EKX41064.1 - 2.6 8.8 0.0 2.6 8.8 0.0 3.4 4 1 0 4 4 4 0 ELM2 domain UQ_con PF00179.26 EKX41065.1 - 9.3e-49 164.7 0.1 1.1e-48 164.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EKX41065.1 - 0.024 14.9 0.4 0.031 14.6 0.4 1.4 1 1 0 1 1 1 0 RWD domain G-patch PF01585.23 EKX41066.1 - 1.1e-11 44.5 0.4 2.4e-11 43.3 0.4 1.5 1 0 0 1 1 1 1 G-patch domain zf-met PF12874.7 EKX41066.1 - 7.5e-07 29.3 0.6 1.7e-06 28.2 0.6 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EKX41066.1 - 1.2e-06 28.6 4.9 2.6e-06 27.6 4.9 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding G-patch_2 PF12656.7 EKX41066.1 - 2.6e-05 24.2 0.0 0.0019 18.3 0.0 2.8 2 0 0 2 2 2 1 G-patch domain zf-C2H2_2 PF12756.7 EKX41066.1 - 0.024 15.0 1.5 0.063 13.6 1.5 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Rep_fac-A_C PF08646.10 EKX41066.1 - 0.047 13.4 0.5 0.091 12.5 0.5 1.5 1 0 0 1 1 1 0 Replication factor-A C terminal domain zf-DBF PF07535.12 EKX41066.1 - 0.059 13.5 6.7 0.13 12.3 6.7 1.5 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2_4 PF13894.6 EKX41066.1 - 0.065 14.1 0.1 0.15 13.0 0.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EKX41066.1 - 0.094 13.2 1.4 0.18 12.3 1.4 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type U-box PF04564.15 EKX41068.1 - 3.5e-19 68.8 0.0 4e-19 68.6 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX41068.1 - 2.8e-05 23.8 0.0 3.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EKX41068.1 - 0.00012 22.0 0.0 0.00019 21.4 0.0 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-NOSIP PF15906.5 EKX41068.1 - 0.047 13.8 0.0 0.06 13.5 0.0 1.2 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_2 PF13923.6 EKX41068.1 - 0.059 13.2 0.0 0.081 12.8 0.0 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pkinase_Tyr PF07714.17 EKX41069.1 - 2.8e-39 135.0 0.0 3.1e-39 134.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX41069.1 - 9.7e-16 57.9 0.0 1.2e-15 57.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 EKX41070.1 - 2.3e-12 47.3 0.0 2.3e-06 28.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX41070.1 - 5e-11 42.9 0.0 9.4e-05 22.9 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX41070.1 - 5.6e-09 36.1 0.3 0.036 14.4 0.0 3.4 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX41070.1 - 2.9e-06 27.2 0.0 0.98 10.2 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EKX41070.1 - 0.00052 20.3 0.1 2.1 8.9 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat WD40 PF00400.32 EKX41071.1 - 3.6e-30 103.6 35.9 0.00017 22.3 0.0 15.9 16 0 0 16 16 16 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX41071.1 - 1.3e-14 54.3 0.2 0.023 15.0 0.0 8.9 7 3 2 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain HELP PF03451.14 EKX41071.1 - 1.8e-09 37.3 0.1 0.0006 19.6 0.0 3.3 4 0 0 4 4 4 2 HELP motif DUF4515 PF14988.6 EKX41071.1 - 0.15 11.9 5.4 0.3 10.9 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) LPD22 PF18834.1 EKX41071.1 - 0.19 12.0 0.8 0.38 11.0 0.8 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 22 FAM76 PF16046.5 EKX41071.1 - 0.25 10.7 1.6 0.48 9.7 1.6 1.4 1 0 0 1 1 1 0 FAM76 protein LUC7 PF03194.15 EKX41071.1 - 0.51 10.0 3.9 0.99 9.0 3.9 1.4 1 0 0 1 1 1 0 LUC7 N_terminus PA26 PF04636.13 EKX41071.1 - 5.3 5.9 5.6 8.6 5.2 5.6 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) WD40 PF00400.32 EKX41072.1 - 1.6e-20 73.0 16.6 0.0033 18.2 0.0 10.2 10 0 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX41072.1 - 7.2e-07 29.4 0.6 0.019 15.3 0.0 5.2 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EKX41072.1 - 0.00017 21.2 0.1 0.00051 19.7 0.1 1.9 2 0 0 2 2 2 1 PQQ-like domain zf-RING_UBOX PF13445.6 EKX41073.1 - 1.2e-08 34.8 3.9 1.2e-08 34.8 3.9 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EKX41073.1 - 2.5e-08 33.6 4.9 4e-08 33.0 4.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX41073.1 - 1.6e-07 31.2 9.0 3e-07 30.3 9.0 1.5 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EKX41073.1 - 2.7e-07 30.3 10.9 3.9e-07 29.8 10.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX41073.1 - 3.6e-07 29.9 8.8 5.9e-07 29.3 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EKX41073.1 - 3.7e-07 30.2 8.6 2.2e-06 27.7 8.7 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EKX41073.1 - 7.7e-06 25.7 8.8 0.00013 21.8 9.5 2.1 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EKX41073.1 - 0.00011 22.5 10.8 0.00023 21.4 10.9 1.5 1 1 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.6 EKX41073.1 - 0.0013 18.5 7.3 0.0025 17.6 7.3 1.4 1 1 0 1 1 1 1 zf-RING of BARD1-type protein DUF2321 PF10083.9 EKX41073.1 - 0.0025 17.4 2.1 0.017 14.8 0.6 2.0 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2321) zf-rbx1 PF12678.7 EKX41073.1 - 0.011 16.0 8.4 0.026 14.8 8.4 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 EKX41073.1 - 0.018 14.9 6.0 0.83 9.5 3.3 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EKX41073.1 - 0.024 14.8 2.5 0.043 14.0 2.5 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-Nse PF11789.8 EKX41073.1 - 0.1 12.4 6.3 0.21 11.4 6.3 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn-ribbon_8 PF09723.10 EKX41073.1 - 0.18 12.0 8.0 4 7.6 3.8 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DNA_ligase_ZBD PF03119.16 EKX41073.1 - 0.23 11.5 5.4 3.1 7.9 0.5 2.8 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Rad50_zn_hook PF04423.14 EKX41073.1 - 0.44 10.4 7.0 4.2 7.3 1.0 2.6 2 1 0 2 2 2 0 Rad50 zinc hook motif zinc_ribbon_9 PF14369.6 EKX41073.1 - 0.61 10.4 0.2 0.61 10.4 0.2 2.7 2 1 0 2 2 2 0 zinc-ribbon zf-ribbon_3 PF13248.6 EKX41073.1 - 0.68 9.4 7.2 1.5 8.4 0.6 2.6 2 1 0 2 2 2 0 zinc-ribbon domain zf-WRNIP1_ubi PF18279.1 EKX41073.1 - 2.2 9.1 5.2 50 4.9 1.6 2.6 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-H2C2_2 PF13465.6 EKX41073.1 - 9.1 6.9 8.2 1.8 9.1 0.6 2.5 2 1 0 2 2 2 0 Zinc-finger double domain UFC1 PF08694.11 EKX41075.1 - 1.8e-81 271.2 0.1 2.1e-81 271.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.26 EKX41075.1 - 0.0035 17.0 0.2 0.0069 16.0 0.2 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EKX41075.1 - 0.017 15.4 0.0 0.022 15.0 0.0 1.2 1 0 0 1 1 1 0 RWD domain SUIM_assoc PF16619.5 EKX41077.1 - 3.8e-06 26.9 1.2 9.6e-06 25.6 1.2 1.8 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 CNOT1_HEAT PF16418.5 EKX41077.1 - 0.021 14.9 1.4 0.032 14.3 1.4 1.3 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 1 HEAT repeat TFIIA PF03153.13 EKX41077.1 - 0.074 13.0 9.4 0.079 12.9 9.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 EKX41077.1 - 0.091 12.4 11.4 0.1 12.2 11.4 1.2 1 0 0 1 1 1 0 Spt20 family Androgen_recep PF02166.16 EKX41077.1 - 0.63 8.8 13.8 0.75 8.6 13.8 1.1 1 0 0 1 1 1 0 Androgen receptor Med3 PF11593.8 EKX41077.1 - 7.9 5.5 13.5 11 5.0 13.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Methyltr_RsmB-F PF01189.17 EKX41079.1 - 0.0028 17.3 0.1 0.005 16.5 0.1 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F DUF3970 PF13113.6 EKX41080.1 - 0.00087 19.4 0.6 5 7.4 0.1 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3970) WDCP PF15390.6 EKX41080.1 - 2.3 6.5 5.2 0.48 8.7 1.9 1.4 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family Methyltransf_16 PF10294.9 EKX41081.1 - 1.3e-07 31.5 0.0 1.7e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EKX41081.1 - 0.021 14.6 0.0 0.021 14.6 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain RabGAP-TBC PF00566.18 EKX41082.1 - 1e-05 25.3 0.3 0.046 13.4 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain VPS53_C PF16854.5 EKX41083.1 - 0.22 11.4 0.0 0.36 10.7 0.0 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 53 C-terminus HEAT_2 PF13646.6 EKX41085.1 - 3.1e-08 33.9 2.4 0.0015 18.9 0.2 4.0 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.22 EKX41085.1 - 0.00028 20.9 0.4 4.1 7.9 0.0 4.3 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 EKX41085.1 - 0.0079 16.7 0.7 3.6 8.2 0.2 3.8 3 0 0 3 3 3 1 HEAT-like repeat Cnd1 PF12717.7 EKX41085.1 - 0.068 13.2 0.1 2.4 8.2 0.1 2.6 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 EF-hand_7 PF13499.6 EKX41087.1 - 2.9e-05 24.4 0.6 8.8e-05 22.9 0.6 1.8 1 0 0 1 1 1 1 EF-hand domain pair WD40 PF00400.32 EKX41087.1 - 0.0014 19.4 0.5 1.7 9.6 0.0 3.9 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX41087.1 - 0.0017 18.6 0.1 4.9 7.5 0.0 4.3 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_5 PF13202.6 EKX41087.1 - 0.0059 16.0 0.1 0.016 14.7 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 EKX41087.1 - 0.0071 15.8 0.0 0.02 14.4 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 EKX41087.1 - 0.011 15.6 1.5 0.032 14.1 0.5 2.3 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 EKX41087.1 - 0.02 14.8 0.0 0.069 13.1 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain mTERF PF02536.14 EKX41088.1 - 9.2e-42 143.1 0.0 1.1e-41 142.9 0.0 1.0 1 0 0 1 1 1 1 mTERF DbpA PF03880.15 EKX41088.1 - 0.029 14.4 0.0 19 5.4 0.0 3.6 4 0 0 4 4 4 0 DbpA RNA binding domain Pox_E8 PF03394.13 EKX41088.1 - 0.072 12.6 0.0 9.7 5.7 0.0 3.0 3 0 0 3 3 3 0 Poxvirus E8 protein DUF4926 PF16277.5 EKX41088.1 - 0.19 11.1 0.2 1.1 8.7 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4926) SPATA24 PF15175.6 EKX41089.1 - 0.0033 17.4 1.4 0.0045 16.9 1.4 1.3 1 0 0 1 1 1 1 Spermatogenesis-associated protein 24 DMAP1_like PF17024.5 EKX41091.1 - 0.037 14.1 0.1 0.042 14.0 0.1 1.2 1 0 0 1 1 1 0 Putative DMAP1-like HlyIII PF03006.20 EKX41092.1 - 4.5e-46 157.4 15.3 5.2e-46 157.2 15.3 1.0 1 0 0 1 1 1 1 Haemolysin-III related MORN PF02493.20 EKX41094.1 - 1.2e-07 31.2 5.4 0.22 11.5 0.0 3.6 3 0 0 3 3 3 3 MORN repeat IQ PF00612.27 EKX41094.1 - 0.00034 20.2 0.3 0.00034 20.2 0.3 2.0 2 0 0 2 2 2 1 IQ calmodulin-binding motif peroxidase PF00141.23 EKX41096.1 - 2.9e-48 164.5 0.0 4.1e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Ank_5 PF13857.6 EKX41096.1 - 4.3e-13 49.2 0.3 3.9e-12 46.2 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX41096.1 - 7.2e-12 45.7 0.0 8.2e-07 29.5 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX41096.1 - 3e-10 40.4 0.0 3.7e-05 24.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX41096.1 - 6.2e-10 39.1 0.1 0.00033 21.0 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EKX41096.1 - 1.8e-07 30.9 0.1 0.007 16.8 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Smg4_UPF3 PF03467.15 EKX41097.1 - 1.6e-40 139.0 0.4 1.6e-40 139.0 0.4 2.4 3 0 0 3 3 3 1 Smg-4/UPF3 family RRM_1 PF00076.22 EKX41097.1 - 0.018 14.9 0.0 0.05 13.4 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cpn60_TCP1 PF00118.24 EKX41097.1 - 0.11 11.0 0.6 0.15 10.6 0.6 1.1 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family Pap_E4 PF02711.14 EKX41097.1 - 0.26 12.3 6.8 12 6.9 2.2 2.7 2 0 0 2 2 2 0 E4 protein His_Phos_1 PF00300.22 EKX41098.1 - 8.9e-19 67.9 0.1 1.1e-17 64.4 0.1 2.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PIN_4 PF13638.6 EKX41099.1 - 6e-20 71.9 0.0 1.1e-19 71.0 0.0 1.5 1 0 0 1 1 1 1 PIN domain CAF1A PF12253.8 EKX41100.1 - 7.1e-07 29.3 0.1 7.1e-07 29.3 0.1 6.1 5 2 0 5 5 5 2 Chromatin assembly factor 1 subunit A AAT PF03417.16 EKX41100.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase CPP1-like PF11833.8 EKX41100.1 - 1.7 8.3 4.7 6.2 6.4 4.7 2.0 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like PEPCK_N PF17297.2 EKX41100.1 - 2.2 7.8 6.2 0.19 11.3 0.9 2.0 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase N-terminal domain Myb_DNA-binding PF00249.31 EKX41101.1 - 2.3e-32 110.9 3.9 2.1e-17 63.1 0.1 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX41101.1 - 1.9e-23 82.5 6.9 1.6e-15 57.1 1.5 2.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EKX41101.1 - 5.8e-08 32.5 0.3 0.0041 17.0 0.0 2.1 1 1 1 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 EKX41101.1 - 0.0015 18.7 0.7 0.13 12.5 0.4 2.8 1 1 1 2 2 2 1 Rap1 Myb domain SLIDE PF09111.10 EKX41101.1 - 0.0068 16.4 0.0 2.7 8.1 0.0 2.3 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_4 PF13837.6 EKX41101.1 - 0.65 10.4 4.2 7 7.1 0.0 3.1 2 2 1 3 3 3 0 Myb/SANT-like DNA-binding domain RRM_2 PF04059.12 EKX41102.1 - 2.3e-45 152.7 0.7 2.7e-45 152.5 0.7 1.1 1 0 0 1 1 1 1 RNA recognition motif 2 BRAP2 PF07576.12 EKX41102.1 - 0.00017 21.7 0.2 0.00022 21.4 0.2 1.2 1 0 0 1 1 1 1 BRCA1-associated protein 2 RRM_1 PF00076.22 EKX41102.1 - 0.00063 19.5 0.6 0.0017 18.1 0.3 1.8 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EKX41102.1 - 0.023 14.9 0.2 0.13 12.5 0.0 2.0 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter PDZ_6 PF17820.1 EKX41103.1 - 1.1e-05 25.2 0.0 2.5e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain CENP-F_leu_zip PF10473.9 EKX41103.1 - 0.001 19.1 10.5 0.0025 17.8 10.1 1.9 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PDZ PF00595.24 EKX41103.1 - 0.024 15.0 0.1 0.053 13.9 0.1 1.6 1 0 0 1 1 1 0 PDZ domain Glutaredoxin2_C PF04399.13 EKX41103.1 - 0.029 14.2 2.6 0.12 12.2 0.9 2.2 1 1 1 2 2 2 0 Glutaredoxin 2, C terminal domain Golgin_A5 PF09787.9 EKX41103.1 - 0.077 12.5 12.2 0.019 14.5 8.7 1.7 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF5082 PF16888.5 EKX41103.1 - 0.094 13.0 3.4 3.2 8.0 3.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) TMPIT PF07851.13 EKX41103.1 - 0.48 9.6 2.2 0.78 8.9 2.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein TMF_DNA_bd PF12329.8 EKX41103.1 - 0.57 10.2 5.8 13 5.8 0.3 2.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ALMT PF11744.8 EKX41103.1 - 0.65 8.8 6.8 1.7 7.4 6.6 1.8 1 1 0 1 1 1 0 Aluminium activated malate transporter FUSC PF04632.12 EKX41103.1 - 0.75 8.3 4.7 0.95 7.9 4.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Angiomotin_C PF12240.8 EKX41103.1 - 0.77 9.3 15.3 0.2 11.2 8.8 2.6 1 1 2 3 3 3 0 Angiomotin C terminal MetOD2 PF18548.1 EKX41103.1 - 2.5 8.3 7.8 0.56 10.3 1.7 2.9 4 0 0 4 4 4 0 Metanogen output domain 2 APG6_N PF17675.1 EKX41103.1 - 2.5 8.6 10.6 5.6 7.5 9.6 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region KxDL PF10241.9 EKX41103.1 - 2.9 8.2 8.4 0.54 10.6 3.2 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein FAM76 PF16046.5 EKX41103.1 - 5.1 6.4 13.5 0.38 10.0 0.4 2.9 1 1 2 3 3 3 0 FAM76 protein G-gamma PF00631.22 EKX41103.1 - 9.1 6.4 6.1 1.7 8.7 0.3 2.6 2 1 1 3 3 3 0 GGL domain DcpS_C PF11969.8 EKX41106.1 - 0.00017 22.1 0.2 0.012 16.1 0.1 2.6 2 1 0 2 2 2 2 Scavenger mRNA decapping enzyme C-term binding DUF440 PF04269.12 EKX41107.1 - 0.0045 17.3 0.4 0.0083 16.4 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF440 DUF4262 PF14081.6 EKX41107.1 - 0.0045 17.2 0.0 0.0087 16.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4262) C2 PF00168.30 EKX41109.1 - 1.3e-10 41.4 0.1 2.5e-10 40.6 0.0 1.5 2 0 0 2 2 2 1 C2 domain Tyr-DNA_phospho PF06087.12 EKX41110.1 - 2e-60 204.9 0.0 2.7e-60 204.5 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Tropomyosin_1 PF12718.7 EKX41111.1 - 0.0054 16.9 11.7 0.0054 16.9 11.7 3.5 3 1 1 4 4 4 1 Tropomyosin like DUF812 PF05667.11 EKX41111.1 - 0.022 13.6 18.7 0.18 10.7 9.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF812) CRISPR_Cse2 PF09485.10 EKX41112.1 - 0.24 11.9 3.0 0.29 11.7 2.6 1.3 1 1 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) DUF1722 PF08349.11 EKX41113.1 - 0.0081 16.4 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1722) CRISPR_Cse2 PF09485.10 EKX41113.1 - 0.015 15.9 0.5 0.018 15.6 0.5 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) DUF1722 PF08349.11 EKX41114.1 - 0.0079 16.5 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1722) CRISPR_Cse2 PF09485.10 EKX41114.1 - 0.015 15.8 0.5 0.019 15.5 0.5 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) DUF1722 PF08349.11 EKX41115.1 - 0.0079 16.5 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1722) CRISPR_Cse2 PF09485.10 EKX41115.1 - 0.015 15.8 0.5 0.019 15.5 0.5 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) DUF1722 PF08349.11 EKX41116.1 - 0.0079 16.5 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1722) CRISPR_Cse2 PF09485.10 EKX41116.1 - 0.015 15.8 0.5 0.019 15.5 0.5 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) DUF1722 PF08349.11 EKX41117.1 - 0.0079 16.5 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1722) CRISPR_Cse2 PF09485.10 EKX41117.1 - 0.015 15.8 0.5 0.019 15.5 0.5 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) DUF1722 PF08349.11 EKX41118.1 - 0.0079 16.5 0.0 0.011 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1722) CRISPR_Cse2 PF09485.10 EKX41118.1 - 0.015 15.8 0.5 0.019 15.5 0.5 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Peptidase_S8 PF00082.22 EKX41119.1 - 3.3e-42 144.8 2.5 5e-42 144.2 2.5 1.3 1 0 0 1 1 1 1 Subtilase family CUB PF00431.20 EKX41119.1 - 2e-28 98.9 0.1 2.2e-09 37.7 0.0 3.6 3 0 0 3 3 3 3 CUB domain PA PF02225.22 EKX41119.1 - 2.9e-11 43.2 0.0 2.1e-10 40.5 0.0 2.3 2 0 0 2 2 2 1 PA domain EGF_Tenascin PF18720.1 EKX41119.1 - 0.017 15.2 10.3 0.048 13.7 10.3 1.9 1 0 0 1 1 1 0 Tenascin EGF domain ZNRF_3_ecto PF18212.1 EKX41119.1 - 0.021 14.8 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 ZNRF-3 Ectodomain Membralin PF09746.9 EKX41120.1 - 1e-13 51.1 0.0 1e-13 51.1 0.0 2.0 1 1 1 2 2 2 1 Tumour-associated protein LRAT PF04970.13 EKX41121.1 - 8e-20 71.4 0.8 2.6e-18 66.5 0.8 2.4 1 1 0 1 1 1 1 Lecithin retinol acyltransferase SVIP PF15811.5 EKX41122.1 - 0.085 13.3 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Small VCP/p97-interacting protein U-box PF04564.15 EKX41123.1 - 3.9e-11 43.0 0.7 7.4e-11 42.1 0.7 1.5 1 0 0 1 1 1 1 U-box domain PAS_9 PF13426.7 EKX41124.1 - 2.1e-08 34.4 0.0 3.7e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EKX41124.1 - 0.00031 20.7 0.0 0.0012 18.8 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_12 PF18095.1 EKX41124.1 - 0.0088 15.7 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 UPF0242 C-terminal PAS-like domain Bromodomain PF00439.25 EKX41125.1 - 4.5e-15 55.5 0.0 4.8e-15 55.4 0.0 1.0 1 0 0 1 1 1 1 Bromodomain Glyco_transf_52 PF07922.11 EKX41126.1 - 0.088 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 52 PYST-C1 PF09690.10 EKX41126.1 - 0.14 11.9 0.2 0.22 11.3 0.2 1.2 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) LRR_4 PF12799.7 EKX41127.1 - 1.8e-26 91.7 38.9 4.8e-08 33.2 0.9 5.0 2 1 5 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX41127.1 - 1.5e-18 66.3 18.0 6.1e-07 29.1 2.3 4.4 2 1 1 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 EKX41127.1 - 1e-10 41.4 9.9 2.2e-08 33.8 1.1 3.1 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 EKX41127.1 - 3e-05 23.7 19.5 0.095 12.8 0.4 6.3 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 EKX41127.1 - 0.023 15.2 11.4 7.8 7.5 0.2 6.0 6 2 0 6 6 6 0 Leucine Rich Repeat Mito_carr PF00153.27 EKX41128.1 - 1.5e-60 201.1 4.9 2.3e-23 81.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Utp14 PF04615.13 EKX41129.1 - 4.9e-120 402.4 124.5 2.9e-119 399.9 111.7 4.3 1 1 1 2 2 2 1 Utp14 protein MFS_1 PF07690.16 EKX41130.1 - 1.4e-17 63.7 40.5 4.9e-15 55.3 30.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EKX41130.1 - 2.9e-06 26.1 29.4 7.6e-05 21.4 28.6 2.7 1 1 1 2 2 2 2 MFS/sugar transport protein Hydrolase_6 PF13344.6 EKX41131.1 - 1.1e-32 112.2 0.0 2.1e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EKX41131.1 - 8.6e-20 70.6 0.0 3.3e-19 68.7 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EKX41131.1 - 1.4e-11 45.1 0.0 4.7e-11 43.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EKX41131.1 - 3.5e-08 33.7 0.1 0.0038 17.3 0.0 2.8 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EKX41131.1 - 6.8e-05 22.5 0.0 0.00031 20.4 0.0 2.0 3 0 0 3 3 3 1 Mitochondrial PGP phosphatase Acid_phosphat_B PF03767.14 EKX41131.1 - 0.085 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF2608 PF11019.8 EKX41131.1 - 0.15 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) RRM_1 PF00076.22 EKX41133.1 - 0.026 14.4 0.0 0.21 11.4 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 EKX41133.1 - 0.89 10.2 7.0 3.1 8.5 0.2 4.0 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal TPR_14 PF13428.6 EKX41134.1 - 3.4e-16 58.5 14.1 0.9 10.5 0.1 12.7 8 4 5 13 13 13 3 Tetratricopeptide repeat Suf PF05843.14 EKX41134.1 - 9.5e-14 52.1 23.5 0.0024 17.9 2.5 7.5 2 2 4 6 6 6 4 Suppressor of forked protein (Suf) TPR_2 PF07719.17 EKX41134.1 - 5.5e-08 32.3 18.1 0.43 10.8 0.0 9.3 11 0 0 11 11 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX41134.1 - 2.1e-07 30.6 11.1 1.1 9.6 0.0 8.6 10 0 0 10 10 10 3 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EKX41134.1 - 2.3e-06 27.6 22.9 0.56 10.2 0.1 8.1 6 4 1 8 8 8 4 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 EKX41134.1 - 6.9e-06 26.3 6.1 0.96 9.8 0.0 6.6 6 1 0 6 6 6 1 Tetratricopeptide repeat NRDE-2 PF08424.10 EKX41134.1 - 1e-05 24.8 24.4 0.018 14.2 2.4 6.4 2 2 2 5 5 5 3 NRDE-2, necessary for RNA interference TPR_15 PF13429.6 EKX41134.1 - 1.6e-05 24.3 17.5 0.14 11.4 0.6 4.7 2 1 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 EKX41134.1 - 0.0011 19.2 0.3 60 4.3 0.1 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat PPP4R2 PF09184.11 EKX41134.1 - 0.0034 17.0 5.7 0.0034 17.0 5.7 1.9 2 0 0 2 2 1 1 PPP4R2 TPR_1 PF00515.28 EKX41134.1 - 0.022 14.6 4.6 57 3.8 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Clathrin PF00637.20 EKX41134.1 - 0.03 14.2 6.5 0.51 10.2 0.0 4.7 4 1 1 5 5 5 0 Region in Clathrin and VPS TPR_7 PF13176.6 EKX41134.1 - 0.064 13.3 7.5 2.8 8.2 0.0 5.9 7 0 0 7 7 5 0 Tetratricopeptide repeat Med13_C PF06333.12 EKX41134.1 - 0.14 11.4 4.4 0.24 10.6 4.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Phage_int_SAM_4 PF13495.6 EKX41134.1 - 0.23 12.0 2.0 1.3 9.6 2.0 2.3 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain PPR PF01535.20 EKX41134.1 - 0.58 10.5 7.4 0.67 10.3 0.0 4.8 7 0 0 7 7 4 0 PPR repeat Sigma70_ner PF04546.13 EKX41134.1 - 7 6.5 14.8 1.5 8.7 9.2 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region Vps36-NZF-N PF16988.5 EKX41135.1 - 0.014 14.8 0.1 0.044 13.2 0.1 1.9 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain ObR_Ig PF18589.1 EKX41135.1 - 0.066 13.6 0.5 0.29 11.5 0.3 2.2 1 1 0 1 1 1 0 Obesity receptor immunoglobulin like domain SNF2_N PF00176.23 EKX41136.1 - 2.3e-27 95.7 0.1 4e-27 94.9 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX41136.1 - 4.1e-08 33.5 0.0 2.4e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HNH PF01844.23 EKX41136.1 - 5.7e-07 29.6 0.5 2.8e-06 27.4 0.5 2.2 1 0 0 1 1 1 1 HNH endonuclease HNH_5 PF14279.6 EKX41136.1 - 0.0022 17.8 0.4 0.0069 16.2 0.4 1.8 1 0 0 1 1 1 1 HNH endonuclease ResIII PF04851.15 EKX41136.1 - 0.0023 18.0 0.0 0.01 15.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EKX41136.1 - 0.006 16.4 0.0 0.015 15.1 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase DEC-1_N PF04625.13 EKX41136.1 - 0.006 15.6 2.7 0.013 14.5 2.7 1.5 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region DUF2052 PF09747.9 EKX41136.1 - 0.0087 16.2 20.1 0.0087 16.2 20.1 2.2 2 0 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) ERCC3_RAD25_C PF16203.5 EKX41136.1 - 0.033 13.4 0.0 0.033 13.4 0.0 1.9 2 0 0 2 2 1 0 ERCC3/RAD25/XPB C-terminal helicase Zn_ribbon_recom PF13408.6 EKX41136.1 - 0.56 10.8 3.5 2.6 8.6 3.5 2.1 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain V_ATPase_I PF01496.19 EKX41136.1 - 2.4 6.0 8.7 4.7 5.0 8.7 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nop14 PF04147.12 EKX41136.1 - 2.4 6.2 31.2 0.021 13.1 23.3 1.4 2 0 0 2 2 2 0 Nop14-like family BUD22 PF09073.10 EKX41136.1 - 5.1 6.3 30.7 0.19 11.0 21.5 2.1 2 0 0 2 2 2 0 BUD22 DUF3899 PF13038.6 EKX41136.1 - 8 7.0 8.4 5.8e+02 1.1 8.4 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3899) CDC45 PF02724.14 EKX41136.1 - 8 4.6 30.9 0.43 8.8 18.2 2.1 2 0 0 2 2 2 0 CDC45-like protein Ion_trans_2 PF07885.16 EKX41140.1 - 0.0021 18.0 2.5 0.0062 16.5 2.5 1.9 1 0 0 1 1 1 1 Ion channel KASH_CCD PF14662.6 EKX41141.1 - 0.0068 16.3 18.1 0.01 15.6 18.1 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH DUF1682 PF07946.14 EKX41141.1 - 0.44 9.7 20.7 0.52 9.5 20.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) V_ATPase_I PF01496.19 EKX41141.1 - 2.3 6.0 10.4 2.8 5.7 10.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF5401 PF17380.2 EKX41141.1 - 2.5 6.1 29.9 1.7 6.6 27.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5401) Presenilin PF01080.17 EKX41141.1 - 6.8 5.4 4.7 8.2 5.1 4.7 1.1 1 0 0 1 1 1 0 Presenilin DUF305 PF03713.13 EKX41142.1 - 5.3e-11 42.9 11.4 1.9e-06 28.1 1.7 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF305) RNase_T PF00929.24 EKX41143.1 - 3.2e-08 34.3 0.0 4.4e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EKX41143.1 - 0.018 14.7 0.1 0.052 13.3 0.1 1.9 1 1 0 1 1 1 0 3'-5' exonuclease Cyclin_N PF00134.23 EKX41144.1 - 1.1e-13 51.1 0.1 1.9e-13 50.2 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain PDZ_2 PF13180.6 EKX41145.1 - 2.9e-15 56.3 0.0 4.5e-07 30.1 0.0 3.0 2 1 1 3 3 3 2 PDZ domain PDZ_6 PF17820.1 EKX41145.1 - 2.9e-15 55.8 0.1 2.2e-06 27.4 0.0 3.0 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 EKX41145.1 - 1.7e-10 41.1 0.2 0.00047 20.5 0.0 2.3 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 EKX41145.1 - 2.1e-05 24.4 0.0 0.097 12.6 0.0 2.4 2 0 0 2 2 2 2 Tricorn protease PDZ domain ISPD_C PF18706.1 EKX41145.1 - 0.17 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain PDZ_6 PF17820.1 EKX41146.1 - 3.5e-06 26.7 0.0 2.9e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX41146.1 - 5.7e-06 26.6 0.0 0.0001 22.6 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX41146.1 - 7.4e-06 26.2 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX41146.1 - 0.038 14.0 0.0 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 Tricorn protease PDZ domain PDZ PF00595.24 EKX41147.1 - 4.6e-06 26.9 0.0 8.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX41147.1 - 0.00031 20.5 0.0 0.00047 19.9 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX41147.1 - 0.00058 20.1 0.0 0.001 19.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Myb_DNA-binding PF00249.31 EKX41148.1 - 1.1e-06 28.7 0.2 2.4e-06 27.6 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX41148.1 - 4.9e-06 26.7 0.6 2.2e-05 24.6 0.6 2.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain PDZ_2 PF13180.6 EKX41148.1 - 0.038 14.3 0.2 0.25 11.7 0.0 2.3 2 0 0 2 2 2 0 PDZ domain SKA2 PF16740.5 EKX41148.1 - 0.054 13.3 1.0 0.32 10.8 0.1 2.8 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Ank_3 PF13606.6 EKX41148.1 - 0.071 13.7 0.8 1.7 9.5 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeat Ank_2 PF12796.7 EKX41148.1 - 0.15 12.7 0.0 7.3 7.3 0.0 2.6 2 1 1 3 3 3 0 Ankyrin repeats (3 copies) DUF3246 PF11596.8 EKX41148.1 - 0.16 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) TolA_bind_tri PF16331.5 EKX41148.1 - 0.19 11.8 2.8 12 6.1 0.6 3.4 2 0 0 2 2 2 0 TolA binding protein trimerisation zf-B_box PF00643.24 EKX41148.1 - 0.66 10.2 7.0 0.12 12.5 2.5 2.0 2 0 0 2 2 2 0 B-box zinc finger C1_4 PF07975.12 EKX41148.1 - 2.2 8.6 5.6 3.2 8.1 2.0 2.7 2 0 0 2 2 2 0 TFIIH C1-like domain PQQ_3 PF13570.6 EKX41150.1 - 5.5e-10 39.4 14.0 0.063 13.8 0.1 7.4 7 0 0 7 7 7 4 PQQ-like domain PQQ_2 PF13360.6 EKX41150.1 - 6.8e-09 35.7 1.3 0.00014 21.5 0.1 3.9 1 1 2 4 4 4 3 PQQ-like domain PQQ PF01011.21 EKX41150.1 - 1.3e-05 24.8 1.1 0.075 13.0 0.0 5.0 5 0 0 5 5 5 1 PQQ enzyme repeat RCC1 PF00415.18 EKX41151.1 - 7.2e-48 161.0 24.2 1.6e-11 44.6 0.2 6.0 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX41151.1 - 2.9e-27 93.9 30.9 6.1e-06 25.9 0.1 6.3 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Kelch_4 PF13418.6 EKX41151.1 - 0.051 13.6 0.1 17 5.5 0.0 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain ATG22 PF11700.8 EKX41152.1 - 4.1e-106 355.5 34.7 4.9e-106 355.2 34.7 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Glyoxalase PF00903.25 EKX41153.1 - 4.1e-12 46.4 0.0 5.4e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EKX41153.1 - 5.2e-08 33.1 0.0 2.5e-07 31.0 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 EKX41153.1 - 0.021 14.8 0.0 0.06 13.3 0.0 1.7 1 1 0 1 1 1 0 Glyoxalase-like domain Glyoxalase_6 PF18029.1 EKX41153.1 - 0.021 15.6 0.0 0.026 15.3 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain CTC1 PF15489.6 EKX41155.1 - 3.1e-07 28.4 0.0 0.00048 17.8 0.0 2.2 2 0 0 2 2 2 2 CST, telomere maintenance, complex subunit CTC1 zf_CCCH_4 PF18345.1 EKX41155.1 - 0.006 16.6 2.5 0.014 15.5 2.5 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EKX41155.1 - 0.1 12.4 0.7 0.32 10.9 0.7 1.9 1 0 0 1 1 1 0 CCCH-type zinc finger Trypsin_2 PF13365.6 EKX41156.1 - 1.9e-32 113.2 0.1 4.1e-32 112.1 0.1 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EKX41156.1 - 8.6e-15 55.1 0.1 1.3e-14 54.5 0.1 1.2 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 EKX41156.1 - 2.9e-12 46.7 0.0 6.9e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Peptidase_S46 PF10459.9 EKX41156.1 - 0.0076 14.9 0.6 0.013 14.2 0.6 1.3 1 0 0 1 1 1 1 Peptidase S46 Peptidase_S32 PF05579.13 EKX41156.1 - 0.0082 15.4 1.1 0.39 9.9 0.4 2.1 2 0 0 2 2 2 1 Equine arteritis virus serine endopeptidase S32 PDZ_6 PF17820.1 EKX41156.1 - 0.022 14.6 0.7 6.1 6.8 0.0 2.7 2 0 0 2 2 2 0 PDZ domain Peptidase_S7 PF00949.21 EKX41156.1 - 0.023 14.5 0.5 0.051 13.4 0.5 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease PDZ PF00595.24 EKX41156.1 - 0.051 13.9 0.3 1.3 9.5 0.3 2.5 1 1 0 1 1 1 0 PDZ domain Xylo_C PF12529.8 EKX41156.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Xylosyltransferase C terminal Peptidase_S29 PF02907.15 EKX41156.1 - 0.13 12.0 0.3 0.29 10.9 0.1 1.6 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease DUF31 PF01732.16 EKX41156.1 - 1.5 8.3 4.6 1 8.8 0.3 2.3 1 1 0 2 2 2 0 Putative peptidase (DUF31) ABC2_membrane PF01061.24 EKX41157.1 - 2.4e-37 128.4 18.3 3.1e-37 128.0 18.3 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EKX41157.1 - 3.8e-24 85.8 0.0 5.4e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EKX41157.1 - 3.9e-06 26.9 0.2 0.007 16.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EKX41157.1 - 3e-05 24.5 0.0 6.7e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EKX41157.1 - 0.00039 20.4 0.3 0.0007 19.5 0.3 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 EKX41157.1 - 0.012 15.2 0.0 0.092 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EKX41157.1 - 0.012 15.6 0.3 0.024 14.7 0.3 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 EKX41157.1 - 0.018 15.1 0.2 0.029 14.4 0.2 1.2 1 0 0 1 1 1 0 Dynamin family AAA_28 PF13521.6 EKX41157.1 - 0.06 13.6 0.0 0.095 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EKX41157.1 - 0.09 12.5 0.3 0.2 11.4 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_35 PF14516.6 EKX41157.1 - 0.14 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_18 PF13238.6 EKX41157.1 - 0.15 12.6 0.1 0.27 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 EKX41157.1 - 0.22 11.6 1.0 0.32 11.0 1.0 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain ABC2_membrane_3 PF12698.7 EKX41157.1 - 0.62 9.1 16.0 0.92 8.5 16.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein UPF0182 PF03699.13 EKX41157.1 - 0.67 8.0 2.9 0.9 7.6 2.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) ADH_zinc_N PF00107.26 EKX41158.1 - 4.1e-30 104.4 1.0 8e-30 103.5 0.3 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EKX41158.1 - 8.9e-24 85.0 0.1 3.4e-23 83.1 0.0 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EKX41158.1 - 2.8e-10 40.0 0.0 8.1e-10 38.6 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EKX41158.1 - 0.0068 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase adh_short PF00106.25 EKX41158.1 - 0.038 13.5 0.4 0.038 13.5 0.4 1.7 2 0 0 2 2 2 0 short chain dehydrogenase ETF PF01012.21 EKX41158.1 - 0.14 12.0 0.7 0.35 10.7 0.7 1.6 1 0 0 1 1 1 0 Electron transfer flavoprotein domain PP2C PF00481.21 EKX41159.1 - 2.7e-51 174.7 0.0 3.1e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EKX41159.1 - 0.078 12.6 0.4 1.1 8.8 0.4 2.1 1 1 0 1 1 1 0 Protein phosphatase 2C DpnD-PcfM PF14207.6 EKX41159.1 - 3.5 7.6 7.9 3.7 7.5 0.4 2.9 2 1 1 3 3 3 0 DpnD/PcfM-like protein zf-CCCH PF00642.24 EKX41160.1 - 7.6e-14 51.2 11.5 3.4e-07 30.0 2.7 2.2 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EKX41160.1 - 0.00038 20.4 17.6 0.0016 18.4 2.4 3.2 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 EKX41160.1 - 0.017 14.9 11.2 0.38 10.6 2.4 2.9 2 1 0 2 2 2 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EKX41160.1 - 0.022 15.2 6.0 1.8 9.1 0.3 2.6 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Brix PF04427.18 EKX41161.1 - 2.4e-40 138.7 0.1 3.3e-40 138.3 0.1 1.2 1 0 0 1 1 1 1 Brix domain GATase_7 PF13537.6 EKX41162.1 - 1.8e-14 53.7 0.0 3.1e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EKX41162.1 - 7.4e-14 52.1 0.0 1.2e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 EKX41162.1 - 0.0001 21.8 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 EKX41162.1 - 0.00051 19.0 0.0 0.0011 17.9 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferases class-II DUF5486 PF17588.2 EKX41163.1 - 0.19 11.6 0.0 0.44 10.5 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5486) Sgf11 PF08209.11 EKX41163.1 - 6.4 6.4 6.9 1.2 8.7 2.0 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) GATase_2 PF00310.21 EKX41164.1 - 1.8e-160 534.3 0.0 2.3e-160 533.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 EKX41164.1 - 9.8e-157 521.8 0.1 1.1e-155 518.3 0.0 2.1 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 EKX41164.1 - 1.9e-105 352.4 0.2 3.6e-104 348.2 0.1 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 EKX41164.1 - 1.5e-71 240.0 8.3 1.5e-71 240.0 8.3 1.7 2 0 0 2 2 2 1 GXGXG motif FMN_dh PF01070.18 EKX41164.1 - 0.012 14.6 1.5 1 8.3 1.9 2.4 2 0 0 2 2 2 0 FMN-dependent dehydrogenase DnaJ_C PF01556.18 EKX41165.1 - 1.8e-31 109.2 0.3 1.8e-24 86.5 0.1 2.2 1 1 1 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.31 EKX41165.1 - 2.2e-22 78.9 0.9 4.1e-22 78.1 0.9 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EKX41165.1 - 6.7e-08 32.8 3.7 1.4e-07 31.8 3.7 1.5 1 0 0 1 1 1 1 DnaJ central domain Collagen PF01391.18 EKX41167.1 - 9.7e-26 89.3 83.3 4.9e-10 39.0 28.1 3.6 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) CutA1 PF03091.15 EKX41168.1 - 2.4e-33 113.9 2.6 8.2e-33 112.2 0.1 2.1 2 0 0 2 2 2 1 CutA1 divalent ion tolerance protein DUF2722 PF10846.8 EKX41168.1 - 0.00068 18.7 1.4 0.00068 18.7 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 EKX41168.1 - 0.0034 17.4 2.7 0.0035 17.4 2.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 EKX41168.1 - 0.18 11.4 13.0 0.25 10.9 13.0 1.1 1 0 0 1 1 1 0 Spt20 family RAB3GAP2_N PF14655.6 EKX41168.1 - 1.2 8.3 5.3 4.2 6.5 4.6 1.9 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Ribosomal_S2 PF00318.20 EKX41169.1 - 9e-27 93.7 0.0 1.1e-12 47.7 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 EKX41169.1 - 0.007 17.7 15.3 0.015 16.6 12.5 2.5 2 1 0 2 2 2 1 40S ribosomal protein SA C-terminus Ribosomal_S2 PF00318.20 EKX41170.1 - 9.2e-27 93.7 0.0 1.1e-12 47.7 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 EKX41170.1 - 0.0078 17.6 15.5 0.017 16.4 12.6 2.6 2 1 0 2 2 2 1 40S ribosomal protein SA C-terminus HAUS6_N PF14661.6 EKX41172.1 - 0.1 12.2 0.4 0.13 11.9 0.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus HI0933_like PF03486.14 EKX41172.1 - 0.14 10.8 0.0 0.17 10.6 0.0 1.0 1 0 0 1 1 1 0 HI0933-like protein Snapin_Pallidin PF14712.6 EKX41173.1 - 7.3e-13 48.7 5.0 7.3e-13 48.7 5.0 1.8 1 1 1 2 2 2 1 Snapin/Pallidin FlaC_arch PF05377.11 EKX41173.1 - 0.018 15.4 4.5 0.19 12.1 0.7 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF489 PF04356.12 EKX41173.1 - 0.028 14.4 3.6 0.035 14.1 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF489) HisKA_2 PF07568.12 EKX41173.1 - 0.044 13.9 1.7 0.059 13.5 0.7 1.8 2 0 0 2 2 2 0 Histidine kinase Phage_HK97_TLTM PF06120.11 EKX41173.1 - 0.11 11.6 8.8 0.18 11.0 8.7 1.3 1 1 0 1 1 1 0 Tail length tape measure protein Hrs_helical PF12210.8 EKX41173.1 - 0.21 12.1 7.0 0.14 12.7 2.4 2.1 1 1 1 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF948 PF06103.11 EKX41173.1 - 0.9 9.8 4.5 1.7 9.0 1.5 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Spectrin PF00435.21 EKX41173.1 - 1.3 9.5 11.9 3.2 8.3 9.1 2.4 1 1 1 2 2 2 0 Spectrin repeat TssO PF17561.2 EKX41173.1 - 1.7 8.8 9.2 0.63 10.1 0.9 2.1 1 1 1 2 2 2 0 Type VI secretion system, TssO Ion_trans PF00520.31 EKX41175.1 - 1.2e-27 96.8 7.4 1.6e-27 96.3 7.4 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX41175.1 - 4.7e-11 42.5 7.8 4.7e-11 42.5 7.8 2.4 2 1 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 EKX41175.1 - 0.016 15.2 0.0 0.063 13.4 0.0 2.0 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain OmpA PF00691.20 EKX41175.1 - 0.065 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 OmpA family IRK PF01007.20 EKX41175.1 - 0.094 12.5 1.2 0.19 11.6 1.2 1.5 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain DUF4293 PF14126.6 EKX41175.1 - 9.7 6.4 7.2 3.8 7.8 1.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4293) Methyltransf_24 PF13578.6 EKX41177.1 - 0.0049 17.9 0.0 0.075 14.1 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain UPF0225 PF17775.1 EKX41180.1 - 2.5e-16 60.3 0.0 3.7e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 UPF0225 domain Pkinase PF00069.25 EKX41183.1 - 7.1e-17 61.6 0.0 1.5e-16 60.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX41183.1 - 0.056 12.7 0.8 0.098 11.9 0.0 1.8 3 0 0 3 3 3 0 Protein tyrosine kinase Tropomyosin PF00261.20 EKX41184.1 - 0.0076 15.6 11.5 0.0076 15.6 11.5 1.9 2 0 0 2 2 2 1 Tropomyosin Phycobilisome PF00502.19 EKX41184.1 - 0.0087 16.0 0.4 0.023 14.6 0.4 1.7 1 0 0 1 1 1 1 Phycobilisome protein Lant_dehydr_C PF14028.6 EKX41184.1 - 0.3 10.6 2.5 11 5.4 0.3 2.3 2 0 0 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term B5 PF03484.15 EKX41184.1 - 0.3 11.4 0.1 0.3 11.4 0.1 3.1 3 1 0 3 3 3 0 tRNA synthetase B5 domain CLZ PF16526.5 EKX41184.1 - 1.4 9.4 8.6 1.6 9.2 1.6 2.9 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TPR_MLP1_2 PF07926.12 EKX41184.1 - 2.2 8.3 20.2 0.25 11.4 3.9 2.9 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein Syntaxin_2 PF14523.6 EKX41184.1 - 5.2 7.5 7.4 2.4 8.6 1.5 3.1 1 1 2 3 3 3 0 Syntaxin-like protein Fib_alpha PF08702.10 EKX41184.1 - 5.7 7.1 9.7 1.4 9.1 3.7 2.7 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family IZUMO PF15005.6 EKX41184.1 - 8.3 6.9 7.0 6.2 7.3 0.1 3.0 3 2 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated WD40 PF00400.32 EKX41185.1 - 5.4e-41 137.8 3.5 8.9e-08 32.7 0.0 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX41185.1 - 1.1e-09 38.4 0.0 0.044 14.1 0.0 3.6 1 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EKX41185.1 - 0.00012 21.6 0.0 0.012 14.9 0.0 2.0 1 1 1 2 2 2 2 WD40-like domain Nup160 PF11715.8 EKX41185.1 - 0.00026 19.8 0.1 0.6 8.7 0.0 3.5 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EKX41185.1 - 0.0029 16.6 0.1 9 5.2 0.0 3.7 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein TetR_C_15 PF17918.1 EKX41186.1 - 0.013 16.2 1.9 0.099 13.4 1.9 2.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain AAA_22 PF13401.6 EKX41186.1 - 0.13 12.5 0.0 0.86 9.9 0.0 2.5 1 0 0 1 1 1 0 AAA domain Phycoerythr_ab PF02972.14 EKX41187.1 - 2.9e-22 78.2 0.2 8.4e-22 76.7 0.0 1.7 2 0 0 2 2 2 1 Phycoerythrin, alpha/beta chain FMN_red PF03358.15 EKX41188.1 - 5.9e-17 61.8 0.0 7.8e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase DEAD PF00270.29 EKX41189.1 - 2e-25 89.5 0.0 4.6e-25 88.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX41189.1 - 2.8e-14 53.4 0.2 7.3e-14 52.1 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX41189.1 - 4.7e-09 36.5 0.0 8.9e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EKX41189.1 - 0.003 17.9 0.0 0.014 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain Pox_Ag35 PF03286.14 EKX41189.1 - 0.58 9.9 3.4 1.2 8.9 3.4 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PPTA PF01239.22 EKX41190.1 - 0.0082 15.8 1.2 0.048 13.4 0.2 2.5 2 1 0 2 2 2 1 Protein prenyltransferase alpha subunit repeat BNIP2 PF12496.8 EKX41191.1 - 0.8 10.1 8.5 0.13 12.7 0.7 2.5 2 1 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Hemerythrin PF01814.23 EKX41192.1 - 3e-13 50.5 4.5 3e-13 50.5 4.5 2.9 2 1 0 2 2 2 1 Hemerythrin HHE cation binding domain DUF922 PF06037.11 EKX41192.1 - 0.055 13.3 1.2 1.2 9.0 0.0 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF922) CopG_antitoxin PF12441.8 EKX41192.1 - 0.099 13.2 1.0 0.2 12.2 0.1 2.1 2 0 0 2 2 2 0 CopG antitoxin of type II toxin-antitoxin system SNARE_assoc PF09335.11 EKX41193.1 - 1.6e-15 57.7 6.7 1.6e-15 57.7 6.7 2.4 1 1 1 2 2 2 1 SNARE associated Golgi protein zf_C2HC_14 PF18574.1 EKX41193.1 - 0.015 15.1 3.2 0.04 13.7 1.7 2.1 2 0 0 2 2 2 0 C2HC Zing finger domain cNMP_binding PF00027.29 EKX41194.1 - 1.3e-08 34.8 0.0 2.8e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EKX41194.1 - 7e-07 29.1 8.1 7e-07 29.1 8.1 2.7 3 1 0 3 3 3 1 Ion channel CnrY PF17524.2 EKX41195.1 - 0.097 12.9 0.1 0.35 11.1 0.1 1.9 1 0 0 1 1 1 0 Anti-sigma factor CnrY cNMP_binding PF00027.29 EKX41196.1 - 6.8e-12 45.3 0.0 1.4e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EKX41196.1 - 1.3e-09 37.9 5.7 1.3e-09 37.9 5.7 2.5 2 1 0 2 2 2 1 Ion channel Ion_trans PF00520.31 EKX41196.1 - 6.5e-09 35.4 21.9 1.2e-08 34.5 21.9 1.3 1 0 0 1 1 1 1 Ion transport protein zinc_ribbon_10 PF10058.9 EKX41197.1 - 0.003 17.3 0.6 0.0053 16.5 0.6 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein PSK_trans_fac PF07704.11 EKX41197.1 - 0.04 14.7 0.0 0.065 14.0 0.0 1.3 1 0 0 1 1 1 0 Rv0623-like transcription factor YdjM PF04307.14 EKX41198.1 - 0.12 11.6 0.1 0.13 11.6 0.1 1.1 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase CTU2 PF10288.9 EKX41199.1 - 0.033 14.4 1.8 0.085 13.1 1.8 1.7 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF4871 PF16167.5 EKX41200.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4871) Methyltransf_16 PF10294.9 EKX41201.1 - 1.1e-07 31.8 0.0 1.4e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase F420H2_quin_red PF04075.14 EKX41201.1 - 0.041 14.0 0.1 0.079 13.1 0.0 1.5 2 0 0 2 2 2 0 F420H(2)-dependent quinone reductase Methyltransf_25 PF13649.6 EKX41201.1 - 0.11 13.2 0.0 0.17 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EKX41201.1 - 0.2 11.0 0.0 0.24 10.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Snapin_Pallidin PF14712.6 EKX41202.1 - 0.41 11.1 20.5 0.12 12.9 5.7 3.6 2 1 1 3 3 3 0 Snapin/Pallidin DUF2229 PF09989.9 EKX41202.1 - 1.2 8.7 11.4 0.64 9.6 3.6 2.4 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) HMMR_N PF15905.5 EKX41202.1 - 1.3 8.4 29.1 0.4 10.1 3.9 2.6 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF5446 PF17522.2 EKX41202.1 - 5.6 7.2 7.5 0.85 9.8 2.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5446) FlgD_ig PF13860.6 EKX41203.1 - 0.0065 16.3 0.1 17 5.4 0.0 4.1 3 0 0 3 3 3 2 FlgD Ig-like domain Peptidase_S74 PF13884.6 EKX41203.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 Chaperone of endosialidase DUF726 PF05277.12 EKX41204.1 - 3.5e-21 75.5 0.0 8.9e-21 74.2 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF726) DUF5626 PF18540.1 EKX41205.1 - 0.043 14.3 0.1 0.083 13.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5626) DUF3709 PF12493.8 EKX41205.1 - 0.043 13.8 1.4 0.08 13.0 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3709) Desulfoferrodox PF01880.18 EKX41206.1 - 2.7e-10 40.7 0.0 3.9e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Desulfoferrodoxin 2OG-FeII_Oxy_3 PF13640.6 EKX41207.1 - 1.6e-07 32.1 0.1 2.6e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 EKX41207.1 - 2.7e-05 24.8 0.0 5.5e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RWP-RK PF02042.15 EKX41208.1 - 2.3e-13 49.9 0.0 3.4e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_3 PF01381.22 EKX41208.1 - 0.091 12.8 0.0 5.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix HTH_31 PF13560.6 EKX41208.1 - 0.14 12.6 0.7 1.3 9.4 0.7 2.5 1 1 0 1 1 1 0 Helix-turn-helix domain RWP-RK PF02042.15 EKX41210.1 - 1.9e-17 63.0 0.1 2.7e-17 62.5 0.1 1.2 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX41210.1 - 0.08 12.7 0.5 0.82 9.5 0.3 2.1 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family PDZ_6 PF17820.1 EKX41211.1 - 1.4e-06 28.0 0.5 3.3e-06 26.8 0.5 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX41211.1 - 3.2e-05 24.2 0.0 9.7e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 PDZ domain RAP PF08373.10 EKX41211.1 - 0.00048 20.2 0.1 0.005 16.9 0.1 2.4 2 0 0 2 2 2 1 RAP domain WW PF00397.26 EKX41211.1 - 0.0076 16.3 11.3 0.01 15.9 6.8 2.6 2 0 0 2 2 2 1 WW domain RRM_1 PF00076.22 EKX41211.1 - 0.021 14.6 0.0 1.7 8.5 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PH PF00169.29 EKX41211.1 - 0.12 12.8 0.1 0.83 10.2 0.0 2.4 2 0 0 2 2 2 0 PH domain Hrs_helical PF12210.8 EKX41211.1 - 0.52 10.9 5.3 20 5.8 2.8 3.7 3 0 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Ank_2 PF12796.7 EKX41212.1 - 1.1e-18 67.6 1.0 6.7e-16 58.7 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX41212.1 - 6.6e-15 55.3 1.9 1.4e-05 25.5 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX41212.1 - 2.8e-14 51.8 0.6 0.0021 18.4 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EKX41212.1 - 4.6e-13 49.0 1.7 2.2e-05 24.7 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EKX41212.1 - 4.2e-11 42.9 3.9 5.3e-05 23.4 0.3 4.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) DUF4314 PF14192.6 EKX41212.1 - 0.08 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4314) YL1 PF05764.13 EKX41213.1 - 0.17 12.0 21.3 0.19 11.8 21.3 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DUF4404 PF14357.6 EKX41213.1 - 0.17 12.5 5.9 0.45 11.2 5.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) DUF2228 PF10228.9 EKX41213.1 - 0.55 9.9 5.8 0.65 9.7 5.8 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) DNA_pol_phi PF04931.13 EKX41213.1 - 1.3 7.1 20.2 1.4 6.9 20.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Endonuc_Holl PF10107.9 EKX41213.1 - 1.9 8.3 6.7 2.3 8.1 6.7 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase CDC45 PF02724.14 EKX41213.1 - 5.1 5.3 17.4 5.6 5.1 17.4 1.1 1 0 0 1 1 1 0 CDC45-like protein RWP-RK PF02042.15 EKX41214.1 - 6.6e-17 61.2 0.1 9.8e-17 60.7 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX41214.1 - 0.034 13.9 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family V_ATPase_I PF01496.19 EKX41215.1 - 0.00091 17.3 1.6 0.001 17.1 1.6 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family ERM PF00769.19 EKX41215.1 - 0.0022 17.8 11.7 0.0028 17.5 11.7 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family TcpS PF17456.2 EKX41215.1 - 0.0071 16.4 2.3 0.011 15.8 2.3 1.4 1 1 0 1 1 1 1 Toxin-coregulated pilus protein S Fez1 PF06818.15 EKX41215.1 - 0.022 15.2 12.4 0.038 14.4 12.4 1.3 1 0 0 1 1 1 0 Fez1 ADIP PF11559.8 EKX41215.1 - 0.047 13.8 10.1 0.28 11.3 1.6 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding GAS PF13851.6 EKX41215.1 - 0.12 11.8 14.8 0.17 11.2 2.7 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Snapin_Pallidin PF14712.6 EKX41215.1 - 0.15 12.5 6.2 1.2 9.6 0.8 2.4 2 0 0 2 2 2 0 Snapin/Pallidin DUF3450 PF11932.8 EKX41215.1 - 0.19 11.0 9.9 0.2 11.0 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) PRKG1_interact PF15898.5 EKX41215.1 - 0.45 11.4 12.1 0.33 11.9 8.9 2.1 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF4140 PF13600.6 EKX41215.1 - 0.88 10.1 9.0 5.2 7.6 8.7 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DASH_Spc19 PF08287.11 EKX41215.1 - 0.88 9.5 11.8 0.17 11.8 8.3 1.7 2 0 0 2 2 2 0 Spc19 CSN5_C PF18323.1 EKX41215.1 - 1.2 10.1 6.5 0.91 10.5 4.3 2.0 2 1 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain AAA_13 PF13166.6 EKX41215.1 - 2.1 6.9 9.1 0.8 8.3 1.9 2.0 1 1 0 2 2 2 0 AAA domain GIT1_C PF12205.8 EKX41215.1 - 3 8.0 6.6 1.8 8.7 1.2 2.3 1 1 1 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term PI3K_P85_iSH2 PF16454.5 EKX41215.1 - 3 7.4 12.7 9.9 5.7 12.7 1.7 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FlaC_arch PF05377.11 EKX41215.1 - 4.8 7.7 8.3 8.6 6.8 2.8 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF2868 PF11067.8 EKX41215.1 - 6.3 6.2 7.3 51 3.2 7.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2868) DUF1664 PF07889.12 EKX41215.1 - 6.6 6.8 8.0 7.8 6.6 4.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fmp27_WPPW PF10359.9 EKX41215.1 - 7.7 5.2 10.3 9.8 4.9 0.4 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DivIC PF04977.15 EKX41215.1 - 8.4 6.2 9.0 6.4 6.6 0.5 2.8 2 1 0 2 2 2 0 Septum formation initiator zf-RING_2 PF13639.6 EKX41216.1 - 2.6e-14 53.2 7.0 4.3e-14 52.6 7.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX41216.1 - 1.1e-11 44.3 6.4 1.7e-11 43.7 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX41216.1 - 2e-09 37.2 4.4 3.2e-09 36.5 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EKX41216.1 - 2.3e-09 36.8 2.2 2.3e-09 36.8 2.2 1.8 2 0 0 2 2 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EKX41216.1 - 5.5e-09 36.2 6.2 1e-08 35.3 6.2 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EKX41216.1 - 1.1e-08 35.0 1.3 1.1e-08 35.0 1.3 1.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EKX41216.1 - 3.9e-08 33.1 3.0 5.6e-08 32.6 3.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EKX41216.1 - 5e-07 29.5 3.1 7.6e-07 28.9 3.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX41216.1 - 2.5e-05 24.0 4.5 6.7e-05 22.7 4.7 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EKX41216.1 - 0.00057 19.9 2.4 0.00086 19.3 2.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 EKX41216.1 - 0.0071 16.4 4.1 0.019 15.1 4.2 1.7 1 1 0 1 1 1 1 RING-variant domain zf-RING-like PF08746.11 EKX41216.1 - 0.011 16.0 3.6 0.02 15.2 3.6 1.5 1 1 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 EKX41216.1 - 0.013 15.3 5.5 0.024 14.5 5.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 EKX41216.1 - 0.027 14.1 4.7 0.05 13.2 4.7 1.5 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 EKX41216.1 - 0.096 12.5 1.5 0.13 12.1 1.5 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RecR PF02132.15 EKX41216.1 - 0.097 12.3 1.2 2.6 7.7 0.2 2.4 2 0 0 2 2 2 0 RecR protein zf-C3HC4_4 PF15227.6 EKX41216.1 - 0.11 12.6 3.0 0.38 11.0 3.0 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 EKX41216.1 - 0.16 12.0 4.7 0.42 10.7 4.7 1.8 1 1 0 1 1 1 0 Zinc-finger zf-RING_10 PF16685.5 EKX41216.1 - 0.47 10.6 3.9 0.77 9.9 3.9 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 FANCL_C PF11793.8 EKX41216.1 - 1 9.6 6.9 5 7.4 6.9 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain SET PF00856.28 EKX41217.1 - 0.00062 20.2 0.0 0.0014 19.0 0.0 1.6 2 0 0 2 2 2 1 SET domain DICT PF10069.9 EKX41217.1 - 0.11 12.3 0.1 0.27 11.0 0.0 1.7 2 0 0 2 2 2 0 Sensory domain in DIguanylate Cyclases and Two-component system SPX PF03105.19 EKX41218.1 - 5.9e-10 39.6 17.1 1.3e-05 25.3 0.4 4.1 3 1 1 4 4 4 3 SPX domain NYD-SP28 PF14772.6 EKX41219.1 - 1.3e-23 82.9 10.1 1.3e-23 82.9 10.1 5.5 3 1 3 6 6 6 1 Sperm tail NYD-SP28_assoc PF14775.6 EKX41219.1 - 2.4e-19 69.2 2.5 2.4e-19 69.2 2.5 5.0 4 2 1 5 5 5 1 Sperm tail C-terminal domain IFT57 PF10498.9 EKX41219.1 - 0.00075 18.6 32.2 0.00075 18.6 32.2 1.9 2 0 0 2 2 2 1 Intra-flagellar transport protein 57 IBP39 PF11422.8 EKX41219.1 - 0.021 14.6 2.5 0.021 14.6 2.5 2.5 3 0 0 3 3 3 0 Initiator binding protein 39 kDa AbiEii PF08843.11 EKX41219.1 - 0.39 10.6 6.4 0.054 13.4 0.8 2.5 2 1 0 2 2 2 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system Sfi1 PF08457.10 EKX41221.1 - 1.3e-08 33.8 67.8 1.1e-05 24.2 20.3 3.5 1 1 2 3 3 3 2 Sfi1 spindle body protein Glycoprot_B_PH2 PF17417.2 EKX41221.1 - 0.0023 18.2 18.6 1.2 9.5 0.5 5.1 3 1 3 6 6 6 4 Herpesvirus Glycoprotein B PH-like domain Nup35_RRM PF05172.13 EKX41221.1 - 0.035 14.1 8.8 21 5.1 0.8 4.5 1 1 4 5 5 5 0 Nup53/35/40-type RNA recognition motif Di19_C PF14571.6 EKX41221.1 - 0.054 14.0 23.1 22 5.6 0.1 6.7 4 2 3 7 7 7 0 Stress-induced protein Di19, C-terminal Humanin PF15040.6 EKX41221.1 - 0.098 12.1 0.1 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 Humanin family HAD PF12710.7 EKX41221.1 - 0.11 12.8 6.6 13 6.1 0.1 3.7 1 1 2 3 3 3 0 haloacid dehalogenase-like hydrolase LEH PF07858.12 EKX41221.1 - 0.49 10.5 7.5 26 4.9 0.1 4.6 1 1 4 5 5 5 0 Limonene-1,2-epoxide hydrolase catalytic domain DUF3145 PF11343.8 EKX41221.1 - 0.81 9.2 10.2 22 4.6 0.3 3.7 1 1 1 3 3 3 0 Protein of unknown function (DUF3145) DUF769 PF05590.11 EKX41221.1 - 6.3 6.2 12.7 22 4.4 1.0 3.6 1 1 2 3 3 3 0 Xylella fastidiosa protein of unknown function (DUF769) Helicase_C PF00271.31 EKX41223.1 - 0.00099 19.4 0.1 0.0012 19.2 0.1 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AMPK1_CBM PF16561.5 EKX41224.1 - 4.4e-06 26.8 0.7 8.8e-05 22.6 0.0 2.6 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase Aa_trans PF01490.18 EKX41225.1 - 1.7e-20 73.2 24.0 1.2e-14 53.9 10.4 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein XG_FTase PF03254.13 EKX41226.1 - 2.2e-09 36.5 0.0 5e-08 32.0 0.0 2.4 2 1 0 2 2 2 2 Xyloglucan fucosyltransferase FAD_binding_7 PF03441.14 EKX41227.1 - 1.9e-58 197.3 0.1 2.9e-58 196.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EKX41227.1 - 1.2e-14 54.7 0.2 3.6e-13 49.8 0.8 2.2 2 0 0 2 2 2 1 DNA photolyase zf-DNL PF05180.12 EKX41228.1 - 6.5e-24 83.7 0.4 6.9e-24 83.6 0.4 1.0 1 0 0 1 1 1 1 DNL zinc finger Elf1 PF05129.13 EKX41228.1 - 0.0023 17.9 0.3 0.0027 17.7 0.3 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.6 EKX41228.1 - 0.0052 16.7 1.4 0.21 11.6 2.2 2.1 1 1 1 2 2 2 2 zinc-ribbon domain TFIIS_C PF01096.18 EKX41228.1 - 0.079 12.8 4.0 0.62 10.0 4.3 2.1 1 1 1 2 2 2 0 Transcription factor S-II (TFIIS) F-box PF00646.33 EKX41229.1 - 0.003 17.4 3.4 0.057 13.3 0.7 3.4 3 0 0 3 3 3 2 F-box domain DSHCT PF08148.12 EKX41230.1 - 0.0045 16.7 1.5 2 8.0 0.0 3.2 2 1 1 3 3 3 2 DSHCT (NUC185) domain LicD PF04991.13 EKX41230.1 - 0.0055 16.9 4.4 0.0055 16.9 4.4 1.8 1 1 1 2 2 2 1 LicD family Adeno_terminal PF02459.15 EKX41230.1 - 0.01 14.2 1.4 0.014 13.8 1.4 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Cytomega_UL84 PF06284.11 EKX41230.1 - 0.27 9.7 9.5 0.45 8.9 9.5 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein U1snRNP70_N PF12220.8 EKX41230.1 - 0.27 11.9 20.0 1.9 9.2 1.7 2.4 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DASH_Dam1 PF08653.10 EKX41230.1 - 0.36 10.7 1.6 0.67 9.8 0.1 2.2 2 1 0 2 2 2 0 DASH complex subunit Dam1 CCSAP PF15748.5 EKX41230.1 - 0.37 10.9 14.6 0.75 9.9 14.6 1.4 1 1 0 1 1 1 0 Centriole, cilia and spindle-associated Vfa1 PF08432.10 EKX41230.1 - 1.1 9.6 24.5 2.4 8.5 14.0 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 FapA PF03961.13 EKX41230.1 - 2 6.9 17.1 0.06 12.0 9.9 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A Muted PF14942.6 EKX41230.1 - 7.3 6.9 21.6 2.2 8.6 12.8 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein DNA_pol_A PF00476.20 EKX41231.1 - 3.9e-85 286.1 0.0 1.3e-83 281.1 0.0 2.8 2 2 0 2 2 2 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 EKX41231.1 - 4.7e-06 26.4 0.0 8.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease AMPK1_CBM PF16561.5 EKX41232.1 - 5.7e-25 87.3 2.6 1.4e-13 50.9 0.3 2.5 2 0 0 2 2 2 2 Glycogen recognition site of AMP-activated protein kinase CBM53 PF16760.5 EKX41232.1 - 4.2e-05 24.0 5.9 0.021 15.4 0.4 3.6 3 0 0 3 3 3 2 Starch/carbohydrate-binding module (family 53) CBM_48 PF02922.18 EKX41232.1 - 0.0023 18.2 2.0 1.2 9.5 0.1 2.5 2 0 0 2 2 2 2 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Ank_5 PF13857.6 EKX41233.1 - 8e-06 26.0 0.1 0.016 15.5 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX41233.1 - 5.3e-05 23.3 0.1 0.046 14.3 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 EKX41233.1 - 8.9e-05 23.0 0.0 0.0038 17.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX41233.1 - 0.00018 22.0 0.0 0.003 18.1 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX41233.1 - 0.054 14.0 0.0 0.83 10.2 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeat DUF4258 PF14076.6 EKX41233.1 - 0.11 12.9 0.1 0.45 10.9 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4258) Methyltransf_21 PF05050.12 EKX41234.1 - 3.5e-07 30.4 0.0 1.2e-06 28.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase FkbM domain RCC1 PF00415.18 EKX41235.1 - 2.3e-54 181.8 22.8 7.3e-10 39.3 0.5 8.4 8 2 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX41235.1 - 6.3e-37 124.6 30.6 2.1e-11 43.3 0.6 6.6 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat DUF3947 PF13135.6 EKX41236.1 - 0.85 9.9 4.3 1.3 9.2 4.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3947) Lung_7-TM_R PF06814.13 EKX41237.1 - 5.6e-05 22.5 27.1 8.7e-05 21.9 27.1 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF2207 PF09972.9 EKX41237.1 - 5.2 5.7 7.7 5 5.8 5.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Myb_DNA-binding PF00249.31 EKX41239.1 - 1.9e-08 34.4 0.1 1.4e-07 31.6 0.1 1.9 1 1 0 1 1 1 1 Myb-like DNA-binding domain TEA PF01285.18 EKX41239.1 - 0.013 15.6 0.1 0.037 14.1 0.1 1.7 1 1 0 1 1 1 0 TEA/ATTS domain ResIII PF04851.15 EKX41240.1 - 4.7e-06 26.7 0.1 0.026 14.5 0.0 2.9 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit PhoH PF02562.16 EKX41240.1 - 0.0002 20.9 0.0 0.00071 19.1 0.0 1.9 2 0 0 2 2 2 1 PhoH-like protein UvrD_C_2 PF13538.6 EKX41240.1 - 0.00054 19.7 0.0 0.0035 17.1 0.0 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_7 PF12775.7 EKX41240.1 - 0.012 15.1 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 EKX41240.1 - 0.013 15.9 0.1 0.064 13.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DEAD PF00270.29 EKX41240.1 - 0.017 14.9 0.1 5.5 6.7 0.0 2.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_30 PF13604.6 EKX41240.1 - 0.024 14.3 0.1 0.4 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EKX41240.1 - 0.051 13.3 0.3 1 9.1 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein PIF1 PF05970.14 EKX41240.1 - 0.056 12.6 0.0 0.54 9.4 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_22 PF13401.6 EKX41240.1 - 0.09 13.1 0.2 0.99 9.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 EKX41240.1 - 0.091 12.1 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_12 PF13087.6 EKX41240.1 - 0.13 11.8 0.1 0.9 9.1 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_25 PF13481.6 EKX41240.1 - 0.15 11.6 0.0 0.59 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain zf-C2H2_6 PF13912.6 EKX41242.1 - 0.019 14.9 0.7 0.052 13.6 0.0 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger DUF5330 PF17264.2 EKX41242.1 - 1.4 8.9 3.5 11 6.1 0.5 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5330) Stm1_N PF09598.10 EKX41243.1 - 0.021 15.6 0.7 0.037 14.9 0.7 1.3 1 0 0 1 1 1 0 Stm1 Redoxin PF08534.10 EKX41244.1 - 3.1e-25 88.6 0.0 3.7e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EKX41244.1 - 2.2e-09 37.3 0.0 2.5e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Peptidase_M20 PF01546.28 EKX41245.1 - 9.6e-16 58.1 0.0 4.8e-15 55.8 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EKX41245.1 - 2.6e-15 56.3 0.0 5e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EKX41245.1 - 0.0086 15.8 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 CRAL_TRIO PF00650.20 EKX41247.1 - 3.9e-31 107.9 0.0 5.4e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EKX41247.1 - 0.0033 17.6 0.1 0.0076 16.4 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain SH3_13 PF18335.1 EKX41247.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain Ephrin_rec_like PF07699.13 EKX41248.1 - 7.1e-48 160.2 94.7 1.4e-09 37.6 5.1 7.7 7 1 1 8 8 8 7 Putative ephrin-receptor like NCD3G PF07562.14 EKX41248.1 - 1.4e-07 31.4 79.3 0.026 14.5 2.6 8.4 4 1 5 10 10 10 9 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX41248.1 - 0.0046 17.3 0.3 0.0046 17.3 0.3 10.6 7 4 4 11 11 11 6 TNFR/NGFR cysteine-rich region cEGF PF12662.7 EKX41248.1 - 0.041 13.8 1.4 0.041 13.8 1.4 10.6 12 2 0 12 12 12 0 Complement Clr-like EGF-like hEGF PF12661.7 EKX41248.1 - 5.3 7.8 32.9 8.7 7.2 0.0 9.4 9 0 0 9 9 9 0 Human growth factor-like EGF GPS PF01825.21 EKX41249.1 - 0.0043 17.5 3.4 0.013 16.0 3.4 1.8 1 0 0 1 1 1 1 GPCR proteolysis site, GPS, motif Defensin_int PF17858.1 EKX41249.1 - 0.098 12.7 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 Platypus intermediate defensin-like peptide RIO1 PF01163.22 EKX41250.1 - 4.4e-74 248.2 0.9 5.8e-74 247.8 0.1 1.6 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 EKX41250.1 - 0.004 16.0 0.1 0.004 16.0 0.1 1.9 1 1 1 2 2 2 1 Fungal protein kinase CDC45 PF02724.14 EKX41250.1 - 0.013 13.9 7.3 0.018 13.4 7.3 1.2 1 0 0 1 1 1 0 CDC45-like protein APH PF01636.23 EKX41250.1 - 0.038 13.9 0.1 2.1 8.2 0.1 2.4 1 1 0 2 2 2 0 Phosphotransferase enzyme family TLP-20 PF06088.11 EKX41250.1 - 0.052 13.4 3.5 0.1 12.5 3.5 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) TFB6 PF17110.5 EKX41250.1 - 0.21 11.3 4.6 0.66 9.7 4.6 1.8 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH SPG4 PF17325.2 EKX41250.1 - 0.28 12.3 4.4 0.69 11.0 3.9 2.0 1 1 0 1 1 1 0 Stationary phase protein 4 DNA_pol_phi PF04931.13 EKX41250.1 - 0.43 8.6 11.9 0.59 8.2 11.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi CSRNP_N PF16019.5 EKX41250.1 - 1.1 9.1 6.0 2 8.3 6.0 1.5 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus SDA1 PF05285.12 EKX41250.1 - 2.6 7.4 19.0 0.28 10.6 14.5 1.6 2 0 0 2 2 2 0 SDA1 Astro_capsid_p PF12226.8 EKX41250.1 - 4.2 6.4 12.4 6.9 5.7 12.4 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein LAT PF15234.6 EKX41250.1 - 4.3 7.0 9.5 7.1 6.3 9.5 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells Abhydrolase_1 PF00561.20 EKX41251.1 - 1.1e-08 35.1 0.0 1.3e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 EKX41251.1 - 1.1e-07 31.7 0.0 1.2e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 EKX41251.1 - 1.9e-07 30.6 0.0 1.1e-06 28.1 0.0 1.8 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EKX41251.1 - 9.5e-05 22.2 0.1 0.0012 18.6 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 EKX41251.1 - 0.0015 18.1 1.5 0.63 9.6 0.2 2.1 2 0 0 2 2 2 2 Lipid-droplet associated hydrolase Peptidase_S15 PF02129.18 EKX41251.1 - 0.0025 17.4 0.2 0.0088 15.7 0.1 1.6 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 EKX41251.1 - 0.019 14.5 0.2 0.14 11.6 0.1 2.0 1 1 1 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EKX41251.1 - 0.023 15.3 0.0 0.023 15.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family C2 PF00168.30 EKX41252.1 - 3.4e-08 33.7 0.0 6.1e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain GST_C_3 PF14497.6 EKX41252.1 - 0.0034 17.5 0.0 0.008 16.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 EKX41253.1 - 4.9e-91 305.2 0.0 6.4e-91 304.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EKX41253.1 - 6.2e-07 28.5 0.1 0.00087 18.1 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EKX41253.1 - 0.0031 15.8 0.0 0.13 10.5 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.21 EKX41253.1 - 0.0068 15.3 0.3 0.017 14.1 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain Ephrin_rec_like PF07699.13 EKX41254.1 - 4.3e-35 119.2 52.4 1.2e-07 31.4 0.7 6.4 6 0 0 6 6 6 6 Putative ephrin-receptor like NCD3G PF07562.14 EKX41254.1 - 3.9e-05 23.5 61.4 0.028 14.4 0.3 7.4 4 2 1 7 7 7 7 Nine Cysteines Domain of family 3 GPCR hEGF PF12661.7 EKX41254.1 - 0.063 13.9 26.2 0.86 10.3 0.2 7.6 7 0 0 7 7 7 0 Human growth factor-like EGF Opy2 PF09463.10 EKX41254.1 - 0.13 12.6 0.7 0.13 12.6 0.7 8.9 6 4 4 10 10 10 0 Opy2 protein EGF_MSP1_1 PF12946.7 EKX41254.1 - 0.62 10.2 34.4 0.26 11.4 1.4 6.1 6 0 0 6 6 6 0 MSP1 EGF domain 1 Ephrin_rec_like PF07699.13 EKX41255.1 - 1.6e-49 165.5 97.7 9.4e-08 31.7 2.1 10.2 3 3 7 10 10 10 10 Putative ephrin-receptor like NCD3G PF07562.14 EKX41255.1 - 1.2e-07 31.6 82.8 0.0039 17.1 4.5 9.0 4 3 3 9 9 9 6 Nine Cysteines Domain of family 3 GPCR VSP PF03302.13 EKX41255.1 - 2.4e-06 26.7 74.4 0.034 13.0 8.0 5.0 1 1 4 5 5 5 5 Giardia variant-specific surface protein TNFR_c6 PF00020.18 EKX41255.1 - 0.00012 22.4 67.4 0.018 15.4 0.3 11.3 5 4 4 11 11 11 7 TNFR/NGFR cysteine-rich region zf-LYAR PF08790.11 EKX41255.1 - 9.7 6.2 17.7 11 6.0 0.5 5.2 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger Ephrin_rec_like PF07699.13 EKX41256.1 - 1.1e-47 159.6 112.2 9.8e-07 28.4 7.5 8.3 8 0 0 8 8 8 8 Putative ephrin-receptor like EGF_MSP1_1 PF12946.7 EKX41256.1 - 5.4e-18 64.8 87.1 0.011 15.7 3.4 10.1 9 0 0 9 9 9 8 MSP1 EGF domain 1 NCD3G PF07562.14 EKX41256.1 - 2.2e-06 27.5 78.3 0.26 11.3 1.6 8.7 8 0 0 8 8 8 7 Nine Cysteines Domain of family 3 GPCR EGF PF00008.27 EKX41256.1 - 0.00077 19.7 42.8 18 5.8 0.3 10.2 8 0 0 8 8 8 8 EGF-like domain Laminin_EGF PF00053.24 EKX41256.1 - 2.4 8.4 117.5 24 5.2 9.9 8.8 1 1 7 8 8 8 0 Laminin EGF domain cEGF PF12662.7 EKX41256.1 - 2.6 8.0 108.2 1.2 9.1 4.0 10.5 11 0 0 11 11 11 0 Complement Clr-like EGF-like REJ PF02010.15 EKX41257.1 - 7e-39 133.9 0.3 1.2e-38 133.1 0.3 1.3 1 0 0 1 1 1 1 REJ domain EF-hand_6 PF13405.6 EKX41258.1 - 1.9e-14 52.3 3.7 0.023 14.6 0.2 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 EKX41258.1 - 7.1e-12 44.0 2.5 0.18 11.4 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EKX41258.1 - 1.5e-10 41.3 4.2 8.4e-06 26.2 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair zf-RING_2 PF13639.6 EKX41258.1 - 7.8e-08 32.5 3.0 7.8e-08 32.5 3.0 1.7 1 1 1 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EKX41258.1 - 5.9e-05 23.0 0.3 0.00037 20.5 0.5 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EKX41258.1 - 0.00019 21.2 7.7 0.015 15.1 1.3 2.3 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EKX41258.1 - 0.00043 20.1 3.5 0.00048 19.9 2.8 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EKX41258.1 - 0.0025 17.5 1.4 0.005 16.6 0.8 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EKX41258.1 - 0.0027 17.5 9.1 0.017 14.9 6.4 2.3 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Zn-C2H2_12 PF18112.1 EKX41258.1 - 0.0052 17.2 3.4 0.079 13.4 0.2 2.8 2 0 0 2 2 2 1 Autophagy receptor zinc finger-C2H2 domain zf-ANAPC11 PF12861.7 EKX41258.1 - 0.0064 16.5 4.2 0.029 14.4 4.1 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger EF-hand_8 PF13833.6 EKX41258.1 - 0.0096 15.8 0.9 7.9 6.4 0.0 3.6 4 0 0 4 4 4 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX41258.1 - 0.014 15.8 0.4 0.14 12.5 0.0 2.3 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region zf-RING_5 PF14634.6 EKX41258.1 - 0.032 14.2 8.1 0.13 12.3 6.2 2.2 1 1 1 2 2 2 0 zinc-RING finger domain EF-hand_5 PF13202.6 EKX41258.1 - 0.04 13.4 4.5 0.22 11.1 0.0 3.8 4 0 0 4 4 4 0 EF hand zf-C3HC4_4 PF15227.6 EKX41258.1 - 0.062 13.5 5.7 1.8 8.8 0.1 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-HC5HC2H_2 PF13832.6 EKX41258.1 - 0.07 13.3 2.5 0.12 12.5 2.5 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-rbx1 PF12678.7 EKX41258.1 - 0.16 12.3 9.4 0.84 10.0 9.5 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EKX41258.1 - 0.17 11.8 6.6 2.6 8.0 1.9 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-UDP PF14569.6 EKX41258.1 - 0.37 10.9 2.8 1.9 8.7 2.8 2.0 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 EKX41258.1 - 0.66 9.8 6.9 2.8 7.8 4.9 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.11 EKX41258.1 - 0.67 9.9 2.7 2.2 8.2 0.7 2.3 2 1 1 3 3 2 0 Baculovirus immediate-early protein (IE-0) Methyltransf_24 PF13578.6 EKX41259.1 - 4.5e-07 30.9 0.0 7.1e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain C2 PF00168.30 EKX41260.1 - 1.3e-11 44.7 0.4 4.8e-11 42.8 0.4 1.9 1 1 1 2 2 2 1 C2 domain PDZ_2 PF13180.6 EKX41260.1 - 3.4e-07 30.5 0.1 7.8e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX41260.1 - 6.1e-07 29.2 0.5 3e-06 27.0 0.2 2.1 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX41260.1 - 5.4e-05 23.5 0.1 0.00011 22.4 0.1 1.5 1 0 0 1 1 1 1 PDZ domain IBN_N PF03810.19 EKX41261.1 - 6.7e-15 54.8 0.0 3.8e-13 49.2 0.0 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cnd1 PF12717.7 EKX41261.1 - 0.0075 16.3 0.5 0.034 14.2 0.3 2.2 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 EKX41261.1 - 0.012 15.8 0.3 0.13 12.4 0.1 2.6 1 1 1 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 EKX41261.1 - 0.043 14.1 1.8 8.1 7.0 0.0 4.7 4 0 0 4 4 4 0 HEAT repeat SURF2 PF05477.11 EKX41261.1 - 0.21 11.3 0.4 0.35 10.5 0.4 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF3730 PF12530.8 EKX41261.1 - 0.93 9.0 5.9 0.26 10.8 0.5 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3730) Paf1 PF03985.13 EKX41262.1 - 0.034 13.2 34.2 0.036 13.1 34.2 1.0 1 0 0 1 1 1 0 Paf1 Mpp10 PF04006.12 EKX41262.1 - 0.11 10.9 34.0 0.13 10.7 34.0 1.2 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 EKX41262.1 - 0.31 9.2 44.2 0.38 8.9 44.2 1.2 1 0 0 1 1 1 0 Nop14-like family NPR3 PF03666.13 EKX41262.1 - 3.5 6.3 23.6 3.5 6.3 23.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 BUD22 PF09073.10 EKX41262.1 - 5.3 6.3 40.9 5.5 6.2 40.9 1.1 1 0 0 1 1 1 0 BUD22 DUF2956 PF11169.8 EKX41264.1 - 0.021 15.0 1.1 0.06 13.5 1.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2956) Aminotran_3 PF00202.21 EKX41265.1 - 1.5e-59 201.7 0.0 2e-59 201.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III RRM_7 PF16367.5 EKX41266.1 - 0.012 15.7 0.0 0.18 11.9 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif RRM_1 PF00076.22 EKX41266.1 - 0.059 13.2 0.4 0.39 10.6 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop PF01798.18 EKX41268.1 - 1.8e-90 302.4 0.1 5e-90 301.0 0.1 1.7 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EKX41268.1 - 3e-18 65.9 0.9 3e-18 65.9 0.9 2.4 2 0 0 2 2 1 1 NOP5NT (NUC127) domain Nas2_N PF18265.1 EKX41268.1 - 0.023 14.6 0.5 0.078 12.9 0.5 1.9 1 0 0 1 1 1 0 Nas2 N_terminal domain DUF4820 PF16091.5 EKX41268.1 - 0.038 13.4 2.5 0.059 12.7 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Cnd2 PF05786.14 EKX41268.1 - 0.8 8.3 24.3 1.2 7.7 24.3 1.2 1 0 0 1 1 1 0 Condensin complex subunit 2 RR_TM4-6 PF06459.12 EKX41268.1 - 1.4 8.7 14.6 2.3 8.0 14.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 EKX41268.1 - 2 6.6 14.7 3.3 5.9 14.7 1.3 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 EKX41268.1 - 2.4 6.7 27.5 3.5 6.1 27.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF913 PF06025.12 EKX41268.1 - 3.1 6.7 7.5 4.5 6.2 7.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RNA_polI_A34 PF08208.11 EKX41268.1 - 3.7 7.6 31.4 6.6 6.8 31.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RPN2_C PF18004.1 EKX41268.1 - 8.5 6.3 21.1 14 5.6 21.1 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PBP_sp32 PF07222.12 EKX41268.1 - 8.7 5.7 8.9 15 5.0 8.9 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 SDA1 PF05285.12 EKX41269.1 - 0.011 15.2 28.6 0.013 14.9 28.6 1.0 1 0 0 1 1 1 0 SDA1 DUF913 PF06025.12 EKX41269.1 - 0.031 13.3 8.9 0.034 13.1 8.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Spore_coat_CotO PF14153.6 EKX41269.1 - 0.053 13.4 15.2 0.076 12.9 15.2 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Drc1-Sld2 PF11719.8 EKX41269.1 - 0.056 13.0 13.8 0.059 12.9 13.8 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Mpp10 PF04006.12 EKX41269.1 - 0.071 11.5 27.1 0.086 11.3 27.1 1.1 1 0 0 1 1 1 0 Mpp10 protein SpoIIIAH PF12685.7 EKX41269.1 - 0.074 12.9 15.1 0.086 12.7 15.1 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Presenilin PF01080.17 EKX41269.1 - 0.083 11.6 15.8 0.093 11.5 15.8 1.0 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 EKX41269.1 - 0.13 10.6 27.5 0.15 10.3 27.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Gti1_Pac2 PF09729.9 EKX41269.1 - 0.18 11.9 7.9 0.21 11.6 7.9 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family SpoIIP PF07454.11 EKX41269.1 - 0.2 11.1 12.3 0.31 10.5 12.3 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CCDC53 PF10152.9 EKX41269.1 - 0.2 12.1 14.5 0.29 11.5 14.5 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex RP-C_C PF11800.8 EKX41269.1 - 0.25 11.4 7.9 0.32 11.1 7.9 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region DDHD PF02862.17 EKX41269.1 - 0.26 11.4 7.7 0.35 11.0 7.7 1.2 1 0 0 1 1 1 0 DDHD domain Peptidase_S64 PF08192.11 EKX41269.1 - 0.29 9.6 10.4 0.34 9.3 10.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 Nop14 PF04147.12 EKX41269.1 - 0.67 8.1 32.5 0.84 7.8 32.5 1.0 1 0 0 1 1 1 0 Nop14-like family Tim54 PF11711.8 EKX41269.1 - 0.69 8.6 11.7 0.93 8.2 11.7 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Trypan_PARP PF05887.11 EKX41269.1 - 0.74 9.8 5.8 1.1 9.2 5.8 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SAPS PF04499.15 EKX41269.1 - 1 8.1 18.3 1.1 8.0 18.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4746 PF15928.5 EKX41269.1 - 1.1 8.6 18.8 1.5 8.2 18.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Peptidase_S15 PF02129.18 EKX41269.1 - 1.6 8.2 11.7 2 7.9 11.7 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Spt20 PF12090.8 EKX41269.1 - 3 7.4 30.2 3.9 7.0 30.2 1.1 1 0 0 1 1 1 0 Spt20 family CSG2 PF16965.5 EKX41269.1 - 3.5 6.5 5.1 4.3 6.2 5.1 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Zip PF02535.22 EKX41269.1 - 4.8 6.3 10.2 5.8 6.0 10.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2151 PF10221.9 EKX41269.1 - 5 5.6 9.1 5.7 5.4 9.1 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator SLC12 PF03522.15 EKX41269.1 - 5.7 5.8 15.6 6.9 5.6 15.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Lin-8 PF03353.15 EKX41269.1 - 6.6 6.2 21.8 8 5.9 21.8 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Cnd2 PF05786.14 EKX41269.1 - 6.8 5.2 25.2 8.2 4.9 25.2 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 MDM10 PF12519.8 EKX41269.1 - 7 5.4 12.9 8.4 5.1 12.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 PNISR PF15996.5 EKX41269.1 - 7.8 6.7 23.9 9.4 6.5 23.9 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Pex14_N PF04695.13 EKX41269.1 - 8.5 7.0 13.0 12 6.6 13.0 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDC27 PF09507.10 EKX41269.1 - 9.7 5.5 24.5 12 5.2 24.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2009 PF09418.10 EKX41270.1 - 1.6e-175 584.6 0.0 1.9e-175 584.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 EKX41270.1 - 0.00088 19.4 1.9 0.0016 18.6 1.9 1.4 1 0 0 1 1 1 1 B-box zinc finger Tubulin-binding PF00418.19 EKX41270.1 - 0.058 13.4 0.4 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 Tau and MAP protein, tubulin-binding repeat dUTPase_2 PF08761.11 EKX41270.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 dUTPase CEBP_ZZ PF16366.5 EKX41270.1 - 0.22 11.8 3.6 0.46 10.8 3.6 1.4 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain CLTH PF10607.9 EKX41271.1 - 5.8e-31 107.4 3.2 7.7e-31 107.0 3.2 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EKX41271.1 - 3.4e-10 39.5 0.1 7.8e-10 38.4 0.1 1.7 1 0 0 1 1 1 1 LisH Mitoc_mL59 PF18126.1 EKX41272.1 - 6e-12 46.0 7.6 6e-12 46.0 7.6 1.8 1 1 1 2 2 2 1 Mitochondrial ribosomal protein mL59 Nkap_C PF06047.11 EKX41272.1 - 0.072 13.2 4.5 0.11 12.6 4.5 1.3 1 0 0 1 1 1 0 NF-kappa-B-activating protein C-terminal domain TruD PF01142.18 EKX41273.1 - 8.2e-70 235.7 0.0 8.2e-55 186.3 0.0 3.2 2 1 1 3 3 3 3 tRNA pseudouridine synthase D (TruD) DSPc PF00782.20 EKX41274.1 - 3.9e-29 101.1 0.0 4.5e-29 101.0 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX41274.1 - 3.1e-05 23.6 0.0 3.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 EKX41274.1 - 0.0095 15.6 0.1 0.016 14.9 0.1 1.4 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Init_tRNA_PT PF04179.12 EKX41274.1 - 0.13 12.6 0.1 0.18 12.1 0.1 1.2 1 0 0 1 1 1 0 Rit1 DUSP-like domain Myotub-related PF06602.14 EKX41274.1 - 0.2 10.6 1.0 0.38 9.6 0.2 1.7 1 1 1 2 2 2 0 Myotubularin-like phosphatase domain TIG PF01833.24 EKX41276.1 - 1.6e-44 149.9 137.0 3.4e-06 27.0 0.4 29.0 31 0 0 31 31 31 17 IPT/TIG domain Laminin_G_3 PF13385.6 EKX41276.1 - 5.6e-10 39.6 0.0 1.8e-08 34.7 0.0 3.9 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Cadherin_4 PF17803.1 EKX41276.1 - 6.6e-07 29.9 13.1 1.5 9.5 0.0 9.2 8 0 0 8 8 8 2 Bacterial cadherin-like domain Lactonase PF10282.9 EKX41276.1 - 4.5e-05 22.9 0.8 0.78 8.9 0.0 3.5 3 1 1 4 4 4 2 Lactonase, 7-bladed beta-propeller EPTP PF03736.17 EKX41276.1 - 0.00037 20.4 7.5 2.4 8.2 0.1 6.8 5 1 1 6 6 6 1 EPTP domain TIG_2 PF18020.1 EKX41276.1 - 0.0025 18.4 1.9 42 4.9 0.0 6.5 7 0 0 7 7 7 0 TIG domain found in plexin PD40 PF07676.12 EKX41276.1 - 0.017 15.1 0.2 1.2 9.1 0.0 3.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Big_9 PF17963.1 EKX41276.1 - 0.017 15.8 31.1 1.4 9.7 1.9 11.3 10 1 0 10 10 10 0 Bacterial Ig domain DUF3430 PF11912.8 EKX41277.1 - 0.001 19.2 2.8 0.0012 18.9 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) MAP65_ASE1 PF03999.12 EKX41278.1 - 4.8e-56 190.7 31.8 8e-56 190.0 31.8 1.2 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Gal4_dimer PF03902.13 EKX41278.1 - 0.31 11.2 3.1 2.4 8.4 0.2 3.0 2 1 0 2 2 2 0 Gal4-like dimerisation domain Carbpep_Y_N PF05388.11 EKX41278.1 - 0.39 11.3 7.2 0.3 11.6 0.2 3.6 4 0 0 4 4 4 0 Carboxypeptidase Y pro-peptide TRPM_tetra PF16519.5 EKX41278.1 - 0.43 10.7 5.6 3.5 7.8 0.1 3.7 3 0 0 3 3 3 0 Tetramerisation domain of TRPM DUF1018 PF06252.12 EKX41278.1 - 2.9 8.9 12.7 3.6 8.6 0.1 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1018) SET PF00856.28 EKX41279.1 - 7.9e-09 36.1 0.0 1.3e-08 35.5 0.0 1.3 1 0 0 1 1 1 1 SET domain DsbC_N PF10411.9 EKX41279.1 - 0.076 12.5 0.2 1.2 8.6 0.1 2.6 3 0 0 3 3 3 0 Disulfide bond isomerase protein N-terminus GCV_H PF01597.19 EKX41280.1 - 1.9e-42 144.0 0.3 2.2e-42 143.8 0.3 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 EKX41280.1 - 0.052 13.4 0.3 0.1 12.4 0.1 1.6 2 0 0 2 2 2 0 Biotin-requiring enzyme RnfC_N PF13375.6 EKX41280.1 - 0.095 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain GST_C_3 PF14497.6 EKX41281.1 - 6.4e-16 58.4 0.0 1.4e-15 57.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EKX41281.1 - 1.5e-10 41.3 0.0 3.1e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EKX41281.1 - 2e-10 40.7 0.0 2.9e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EKX41281.1 - 3.1e-09 36.7 0.0 1.1e-08 35.0 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EKX41281.1 - 0.01 16.3 0.0 0.019 15.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 EKX41281.1 - 0.01 15.6 0.1 0.046 13.5 0.1 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain MCM PF00493.23 EKX41282.1 - 5.9e-100 333.0 0.1 1.1e-99 332.1 0.1 1.4 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 EKX41282.1 - 6.3e-36 123.0 0.1 1.4e-35 121.8 0.1 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EKX41282.1 - 3.5e-26 91.4 0.2 1.1e-25 89.8 0.2 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EKX41282.1 - 2e-16 60.4 0.1 6e-16 58.9 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain MCM2_N PF12619.8 EKX41282.1 - 8.1e-14 52.2 14.3 8.4e-14 52.1 12.1 2.2 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 Mg_chelatase PF01078.21 EKX41282.1 - 9.7e-09 34.9 0.0 1.1e-06 28.2 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EKX41282.1 - 1.7e-06 28.1 0.0 5.5e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EKX41282.1 - 0.0011 18.9 0.0 0.0048 16.8 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EKX41282.1 - 0.0017 18.1 0.0 0.025 14.3 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 EKX41282.1 - 0.017 15.5 0.0 0.043 14.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zn-ribbon_8 PF09723.10 EKX41282.1 - 0.14 12.3 1.7 0.35 11.0 1.7 1.6 1 0 0 1 1 1 0 Zinc ribbon domain AAA_30 PF13604.6 EKX41282.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain FAM176 PF14851.6 EKX41283.1 - 0.0065 16.1 0.9 0.0065 16.1 0.9 3.1 3 1 0 3 3 3 1 FAM176 family DUF2561 PF10812.8 EKX41283.1 - 0.011 15.8 0.0 0.033 14.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) RP-C_C PF11800.8 EKX41283.1 - 0.021 14.9 0.2 0.021 14.9 0.2 3.7 4 0 0 4 4 4 0 Replication protein C C-terminal region DUF4404 PF14357.6 EKX41283.1 - 0.11 13.1 3.4 0.56 10.9 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) MscS_TM PF12794.7 EKX41283.1 - 0.17 10.7 0.0 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 PRIMA1 PF16101.5 EKX41283.1 - 2.5 8.2 9.2 0.52 10.4 4.8 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 LysM PF01476.20 EKX41284.1 - 0.073 13.2 0.0 0.29 11.2 0.0 2.2 1 0 0 1 1 1 0 LysM domain PDZ_6 PF17820.1 EKX41285.1 - 7.6e-13 48.1 0.0 9.9e-13 47.7 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX41285.1 - 3.6e-10 40.1 0.0 3.8e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX41285.1 - 2.8e-09 37.1 0.1 3.5e-09 36.9 0.1 1.1 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX41285.1 - 2.1e-05 24.4 0.0 2.8e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Tricorn protease PDZ domain Pkinase_Tyr PF07714.17 EKX41286.1 - 1.6e-11 44.0 0.0 1.6e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX41286.1 - 7.8e-08 32.0 0.0 7.8e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EKX41286.1 - 0.002 17.5 0.0 0.0025 17.2 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EKX41286.1 - 0.027 13.3 0.3 0.03 13.1 0.3 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EKX41286.1 - 0.03 14.2 0.1 0.044 13.7 0.0 1.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family U-box PF04564.15 EKX41287.1 - 7.3e-12 45.3 0.1 8.1e-12 45.2 0.1 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX41287.1 - 0.0014 18.4 0.0 0.0023 17.7 0.0 1.5 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 EKX41287.1 - 0.0033 17.5 0.0 0.0038 17.3 0.0 1.1 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein T3SS_NleG PF06416.12 EKX41287.1 - 0.076 12.9 0.1 0.091 12.7 0.1 1.3 1 1 0 1 1 1 0 Effector protein NleG RCC1_2 PF13540.6 EKX41288.1 - 6.3e-13 48.1 31.9 2.2e-05 24.1 1.5 8.0 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EKX41288.1 - 0.00015 22.3 0.2 0.55 10.9 0.1 4.4 4 0 0 4 4 4 1 Regulator of chromosome condensation (RCC1) repeat FapA PF03961.13 EKX41289.1 - 5.4e-05 22.0 1.3 5.4e-05 22.0 1.3 2.8 1 1 2 3 3 3 2 Flagellar Assembly Protein A SPAM PF02090.15 EKX41289.1 - 0.33 10.7 6.8 2.4 7.9 1.1 2.7 2 1 0 2 2 2 0 Salmonella surface presentation of antigen gene type M protein DUF3584 PF12128.8 EKX41289.1 - 2.4 5.5 30.4 3.1 5.2 30.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Kelch_1 PF01344.25 EKX41290.1 - 1.1e-09 37.7 1.9 0.0092 15.5 0.0 6.1 6 0 0 6 6 6 2 Kelch motif Kelch_5 PF13854.6 EKX41290.1 - 1.9e-09 37.3 5.5 0.0065 16.4 0.1 6.1 6 0 0 6 6 6 2 Kelch motif Kelch_4 PF13418.6 EKX41290.1 - 2.1e-08 34.0 11.7 0.042 13.9 0.1 6.6 6 1 0 6 6 6 2 Galactose oxidase, central domain DUF4215 PF13948.6 EKX41290.1 - 1.2e-06 28.8 11.1 1.2e-06 28.8 11.1 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF4215) Kelch_6 PF13964.6 EKX41290.1 - 1.6e-05 25.0 9.0 1.2 9.5 0.0 6.0 5 1 1 6 6 6 3 Kelch motif Kelch_3 PF13415.6 EKX41290.1 - 0.00014 22.1 5.7 0.15 12.4 0.0 5.4 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 EKX41290.1 - 0.023 14.7 5.9 0.88 9.7 0.0 4.8 5 0 0 5 5 5 0 Kelch motif KH_1 PF00013.29 EKX41291.1 - 8.4e-21 73.6 0.4 6.8e-10 38.6 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 EKX41291.1 - 4.2e-06 26.5 2.0 0.036 13.9 0.2 2.3 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 EKX41291.1 - 0.18 11.9 1.4 14 5.8 0.1 2.3 2 0 0 2 2 2 0 NusA-like KH domain SAP PF02037.27 EKX41292.1 - 3.2e-12 45.9 1.0 5.1e-12 45.2 1.0 1.3 1 0 0 1 1 1 1 SAP domain Telomere_Sde2_2 PF13297.6 EKX41292.1 - 0.0075 15.9 0.2 0.014 15.0 0.2 1.4 1 0 0 1 1 1 1 Telomere stability C-terminal RRM_1 PF00076.22 EKX41292.1 - 0.0077 16.0 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TUSC2 PF15000.6 EKX41292.1 - 0.011 16.0 0.1 0.017 15.4 0.1 1.3 1 0 0 1 1 1 0 Tumour suppressor candidate 2 PASTA PF03793.19 EKX41292.1 - 0.027 14.3 0.1 0.097 12.5 0.1 1.9 1 1 1 2 2 2 0 PASTA domain LEM PF03020.15 EKX41292.1 - 0.042 13.4 0.0 0.11 12.1 0.0 1.7 1 1 1 2 2 2 0 LEM domain DDE_Tnp_ISAZ013 PF07592.11 EKX41292.1 - 0.22 10.5 0.0 0.29 10.1 0.0 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain PepSY_2 PF13670.6 EKX41292.1 - 1 9.4 4.8 5.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain DUF3153 PF11353.8 EKX41293.1 - 0.056 13.0 0.3 0.11 12.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) Ig_Tie2_1 PF10430.9 EKX41293.1 - 1 9.9 3.9 3.9 8.0 0.3 2.9 3 0 0 3 3 3 0 Tie-2 Ig-like domain 1 Ion_trans_2 PF07885.16 EKX41294.1 - 1.2e-11 44.4 6.8 2.1e-10 40.4 1.3 4.1 4 0 0 4 4 4 2 Ion channel SK_channel PF03530.14 EKX41294.1 - 6.7e-08 32.5 7.4 0.0019 18.1 0.1 3.3 3 0 0 3 3 3 2 Calcium-activated SK potassium channel Ion_trans PF00520.31 EKX41294.1 - 0.13 11.5 24.0 0.025 13.8 12.3 3.1 2 2 0 2 2 2 0 Ion transport protein zf-RING_2 PF13639.6 EKX41295.1 - 0.0044 17.3 1.6 0.0044 17.3 1.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_14 PF17978.1 EKX41295.1 - 0.048 14.1 0.7 0.1 13.0 0.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 EKX41295.1 - 0.09 12.9 2.0 0.21 11.8 2.0 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_3 PF13920.6 EKX41295.1 - 1 9.3 8.0 3.1 7.7 1.7 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) cNMP_binding PF00027.29 EKX41296.1 - 9e-09 35.3 0.1 1.1e-07 31.8 0.1 2.3 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain MORN PF02493.20 EKX41297.1 - 0.68 10.0 10.8 0.47 10.5 4.5 3.0 3 0 0 3 3 3 0 MORN repeat WD40 PF00400.32 EKX41299.1 - 0.004 17.9 2.8 0.62 11.0 0.0 3.6 3 1 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.8 EKX41299.1 - 0.078 11.6 0.1 0.26 9.9 0.1 1.6 1 1 1 2 2 2 0 Nucleoporin Nup120/160 MOEP19 PF16005.5 EKX41300.1 - 0.0087 16.0 0.1 0.01 15.8 0.1 1.3 1 0 0 1 1 1 1 KH-like RNA-binding domain Cadherin-like PF12733.7 EKX41301.1 - 0.079 13.5 1.0 0.14 12.7 1.0 1.3 1 0 0 1 1 1 0 Cadherin-like beta sandwich domain TORC_C PF12886.7 EKX41301.1 - 0.11 13.0 0.0 32 5.2 0.0 2.7 2 0 0 2 2 2 0 Transducer of regulated CREB activity, C terminus FAST_1 PF06743.15 EKX41301.1 - 0.11 12.4 0.0 0.11 12.4 0.0 4.0 4 1 3 7 7 7 0 FAST kinase-like protein, subdomain 1 Ribosomal_L10 PF00466.20 EKX41303.1 - 1.2e-09 38.2 0.0 1.6e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 RCC1_2 PF13540.6 EKX41304.1 - 7.1e-08 32.1 0.1 1.6e-07 30.9 0.1 1.6 1 0 0 1 1 1 1 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EKX41304.1 - 1.7e-05 25.3 1.4 0.28 11.9 0.0 2.8 2 2 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat CRAL_TRIO PF00650.20 EKX41305.1 - 4.4e-19 68.7 0.0 9e-19 67.7 0.0 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EKX41305.1 - 0.0028 17.8 0.0 0.0049 17.0 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF3504 PF12012.8 EKX41306.1 - 0.078 12.9 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) Nop14 PF04147.12 EKX41306.1 - 0.81 7.8 15.1 1.1 7.4 15.1 1.1 1 0 0 1 1 1 0 Nop14-like family DDRGK PF09756.9 EKX41306.1 - 1.3 8.6 14.3 4.1 7.0 13.4 1.9 2 0 0 2 2 2 0 DDRGK domain RNA_polI_A34 PF08208.11 EKX41306.1 - 1.8 8.6 8.6 2.4 8.2 8.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 SDA1 PF05285.12 EKX41306.1 - 3.2 7.1 16.2 4.5 6.6 16.2 1.2 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 EKX41306.1 - 6 5.9 13.9 8.1 5.5 13.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RPN2_C PF18004.1 EKX41306.1 - 7.7 6.4 8.8 12 5.8 8.8 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain FAM176 PF14851.6 EKX41306.1 - 9.9 5.8 9.3 21 4.8 9.3 1.5 1 0 0 1 1 1 0 FAM176 family Patched PF02460.18 EKX41307.1 - 2.5e-101 340.1 14.7 8.7e-56 189.5 0.4 3.1 3 0 0 3 3 3 3 Patched family Sterol-sensing PF12349.8 EKX41307.1 - 9.5e-45 152.2 13.9 3.2e-42 144.0 1.3 2.7 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 EKX41307.1 - 3.3e-05 21.8 4.3 4.8e-05 21.3 4.3 1.1 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 EKX41307.1 - 0.00046 19.2 4.9 0.00046 19.2 4.9 2.3 2 0 0 2 2 2 1 MMPL family Reo_sigmaC PF04582.12 EKX41307.1 - 0.045 14.0 0.1 0.19 12.0 0.0 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein C-terminal domain PPPI_inhib PF14895.6 EKX41310.1 - 3.9e-12 46.0 2.6 7.7e-12 45.0 2.6 1.6 1 1 0 1 1 1 1 Protein phosphatase 1 inhibitor Abhydrolase_2 PF02230.16 EKX41311.1 - 5.8e-47 160.3 0.0 6.4e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 EKX41311.1 - 4e-07 29.8 0.0 4.9e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EKX41311.1 - 7.6e-07 28.8 0.7 0.00023 20.7 0.1 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EKX41311.1 - 6.4e-06 25.6 0.4 0.0057 15.9 0.0 2.4 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Esterase PF00756.20 EKX41311.1 - 0.0013 18.4 0.1 0.0019 17.9 0.1 1.4 1 1 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 EKX41311.1 - 0.0014 18.6 0.0 0.0055 16.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 EKX41311.1 - 0.0039 16.9 0.0 0.0077 15.9 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EKX41311.1 - 0.012 16.2 0.0 0.032 14.8 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EKX41311.1 - 0.017 14.8 0.3 0.026 14.2 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Mito_carr PF00153.27 EKX41312.1 - 5.1e-64 212.2 3.5 1.3e-21 76.3 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein PDZ PF00595.24 EKX41314.1 - 5.2e-19 68.4 1.5 6.4e-08 32.8 0.7 3.5 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 EKX41314.1 - 7.8e-18 64.1 1.9 1.2e-06 28.3 0.1 3.8 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 EKX41314.1 - 1.7e-13 50.7 4.7 0.00021 21.6 0.1 3.6 3 1 0 3 3 3 3 PDZ domain Tricorn_PDZ PF14685.6 EKX41314.1 - 0.0021 18.0 0.9 8.9 6.4 0.0 3.6 3 0 0 3 3 3 2 Tricorn protease PDZ domain SbcD_C PF12320.8 EKX41314.1 - 0.068 13.5 0.2 0.28 11.5 0.2 2.1 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain SARAF PF06682.12 EKX41315.1 - 6.8e-47 160.7 0.0 8.7e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis ODV-E18 PF10717.9 EKX41315.1 - 0.13 12.2 0.0 0.43 10.5 0.0 1.7 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 zf-C3HC4_3 PF13920.6 EKX41316.1 - 3.9e-06 26.6 15.8 8.7e-06 25.5 15.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UPF0242 PF06785.11 EKX41316.1 - 0.00051 20.2 20.3 0.004 17.3 7.0 2.4 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0242) N-terminus DUF641 PF04859.12 EKX41316.1 - 0.002 18.4 14.5 0.0023 18.3 2.8 2.5 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) Fez1 PF06818.15 EKX41316.1 - 0.0043 17.5 11.6 0.3 11.5 4.8 2.7 2 0 0 2 2 2 2 Fez1 Prok-RING_4 PF14447.6 EKX41316.1 - 0.031 14.1 17.1 0.066 13.1 17.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF2321 PF10083.9 EKX41316.1 - 0.089 12.4 3.6 0.23 11.1 3.6 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) Phage_GP20 PF06810.11 EKX41316.1 - 0.089 12.6 5.7 0.22 11.3 0.5 2.5 2 0 0 2 2 2 0 Phage minor structural protein GP20 Atx10homo_assoc PF09759.9 EKX41316.1 - 0.11 12.6 0.1 0.11 12.6 0.1 4.0 4 0 0 4 4 4 0 Spinocerebellar ataxia type 10 protein domain V_ATPase_I PF01496.19 EKX41316.1 - 0.19 9.6 10.0 0.37 8.6 0.7 2.7 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family Tropomyosin_1 PF12718.7 EKX41316.1 - 0.28 11.4 21.1 0.36 11.0 7.7 3.1 3 0 0 3 3 3 0 Tropomyosin like Filament PF00038.21 EKX41316.1 - 0.36 10.3 16.1 0.23 11.0 1.3 2.4 2 0 0 2 2 2 0 Intermediate filament protein Csm1_N PF18504.1 EKX41316.1 - 0.55 10.6 14.6 0.07 13.5 1.3 3.4 2 1 1 3 3 3 0 Csm1 N-terminal domain ATG16 PF08614.11 EKX41316.1 - 0.68 10.1 20.5 2.1 8.5 6.9 2.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 EKX41316.1 - 0.93 10.2 14.0 4.7 7.9 2.1 3.4 2 1 0 2 2 2 0 SlyX Nup54 PF13874.6 EKX41316.1 - 3 7.9 8.1 1.1 9.3 0.9 2.9 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Spc7 PF08317.11 EKX41316.1 - 3.2 6.6 21.1 2 7.2 4.8 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein CREPT PF16566.5 EKX41316.1 - 3.6 7.8 10.9 6.5 6.9 1.1 2.8 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour ADIP PF11559.8 EKX41316.1 - 5.4 7.1 19.6 4.5 7.3 8.0 2.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Prefoldin_2 PF01920.20 EKX41316.1 - 6.2 6.8 13.6 29 4.7 0.0 3.6 3 0 0 3 3 3 0 Prefoldin subunit End3 PF12761.7 EKX41316.1 - 6.5 6.9 15.8 3.5 7.8 5.7 2.5 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DUF1664 PF07889.12 EKX41316.1 - 8 6.5 15.4 7.2 6.7 1.4 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) DUF4618 PF15397.6 EKX41316.1 - 9.1 5.6 21.3 0.11 11.9 3.5 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4618) adh_short PF00106.25 EKX41317.1 - 9.1e-31 106.8 0.2 1.4e-30 106.2 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EKX41317.1 - 9.2e-27 94.1 0.1 1.6e-26 93.3 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX41317.1 - 4.5e-07 29.9 0.0 7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EKX41317.1 - 0.0035 16.5 0.1 0.0067 15.6 0.1 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EKX41317.1 - 0.0082 15.6 0.1 0.014 14.9 0.1 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EKX41317.1 - 0.013 14.9 0.1 0.02 14.4 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EKX41317.1 - 0.092 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NDUFA12 PF05071.16 EKX41318.1 - 1.3e-21 77.3 1.0 2e-21 76.6 1.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF1501 PF07394.12 EKX41320.1 - 0.26 10.3 4.3 0.31 10.0 4.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Ank_4 PF13637.6 EKX41321.1 - 5.1e-11 42.9 0.1 1.7e-05 25.2 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX41321.1 - 1.5e-09 38.3 0.0 1.5e-05 25.5 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX41321.1 - 8.2e-08 32.4 0.0 5.1e-05 23.5 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX41321.1 - 2e-07 30.7 0.1 0.096 13.3 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 EKX41321.1 - 0.016 15.7 0.0 20 5.9 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat Collagen PF01391.18 EKX41322.1 - 5e-23 80.6 241.2 8.3e-09 35.1 26.3 8.8 3 2 3 6 6 6 3 Collagen triple helix repeat (20 copies) PH PF00169.29 EKX41322.1 - 1.1e-08 35.5 0.1 2.2e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EKX41322.1 - 2.3e-05 24.6 0.2 3.9e-05 23.8 0.2 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PDZ_6 PF17820.1 EKX41322.1 - 0.0017 18.2 0.0 0.0052 16.6 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX41322.1 - 0.13 12.6 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 PDZ domain CBM_20 PF00686.19 EKX41323.1 - 2.1e-17 62.8 0.0 3.4e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Starch binding domain TauD PF02668.16 EKX41324.1 - 3.6e-28 99.1 0.0 6.4e-28 98.3 0.0 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 EKX41324.1 - 0.014 14.5 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 CsiD USP7_C2 PF14533.6 EKX41325.1 - 0.089 12.5 0.1 0.16 11.7 0.1 1.5 1 1 0 1 1 1 0 Ubiquitin-specific protease C-terminal Pkinase PF00069.25 EKX41326.1 - 1.7e-49 168.6 0.0 1.9e-49 168.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX41326.1 - 2.9e-17 62.8 0.0 3.3e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX41326.1 - 0.00065 19.1 0.0 0.0079 15.5 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 EKX41326.1 - 0.00076 19.1 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EKX41326.1 - 0.001 19.0 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX41326.1 - 0.0012 18.3 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EKX41326.1 - 0.025 14.2 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family DUF1679 PF07914.11 EKX41326.1 - 0.053 12.4 0.0 0.072 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Lustrin_cystein PF14625.6 EKX41327.1 - 3.4e-07 30.5 19.4 0.28 11.6 0.3 5.0 1 1 4 5 5 5 4 Lustrin, cysteine-rich repeated domain Granulin PF00396.18 EKX41327.1 - 0.011 16.0 13.4 5.7 7.4 0.2 4.8 1 1 2 4 4 4 0 Granulin CBM_1 PF00734.18 EKX41327.1 - 0.04 13.9 11.8 5.2 7.1 1.1 4.7 1 1 2 3 3 3 0 Fungal cellulose binding domain Dickkopf_N PF04706.12 EKX41327.1 - 0.044 14.3 14.6 0.54 10.8 6.1 4.3 1 1 2 3 3 3 0 Dickkopf N-terminal cysteine-rich region CBM_14 PF01607.24 EKX41327.1 - 0.41 10.8 12.8 4.5 7.5 0.3 3.4 1 1 4 5 5 5 0 Chitin binding Peritrophin-A domain Inhibitor_I36 PF03995.13 EKX41327.1 - 0.73 9.8 24.3 3.8 7.5 0.2 4.9 5 0 0 5 5 5 0 Peptidase inhibitor family I36 Opy2 PF09463.10 EKX41327.1 - 1.9 8.9 14.8 9 6.7 4.9 3.0 1 1 4 5 5 5 0 Opy2 protein CBM_19 PF03427.13 EKX41327.1 - 2.1 8.4 7.7 5.2 7.1 0.2 3.3 1 1 2 3 3 3 0 Carbohydrate binding domain (family 19) Ephrin_rec_like PF07699.13 EKX41327.1 - 6.5 6.6 16.4 4.8 7.0 5.1 3.1 1 1 2 3 3 3 0 Putative ephrin-receptor like EB1 PF03271.17 EKX41328.1 - 3e-19 69.0 1.3 7e-19 67.8 1.3 1.7 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 EKX41328.1 - 3.9e-11 43.1 1.2 6e-11 42.5 0.7 1.5 2 0 0 2 2 2 1 Calponin homology (CH) domain CH_2 PF06294.11 EKX41328.1 - 4.9e-05 23.4 0.2 8.6e-05 22.6 0.2 1.5 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 EKX41328.1 - 0.0066 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain ATG16 PF08614.11 EKX41328.1 - 0.04 14.2 0.6 0.056 13.7 0.6 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Lactamase_B_2 PF12706.7 EKX41329.1 - 2.8e-14 53.1 0.3 2.1e-06 27.4 0.1 2.2 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EKX41329.1 - 1.8e-05 24.8 0.0 0.00033 20.7 0.0 2.4 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 EKX41329.1 - 0.0074 15.9 0.1 0.023 14.4 0.0 1.8 2 0 0 2 2 2 1 tRNase Z endonuclease Methyltransf_31 PF13847.6 EKX41329.1 - 0.17 11.6 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TLD PF07534.16 EKX41330.1 - 6.1e-07 29.7 0.0 8.5e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 TLD Ion_trans PF00520.31 EKX41331.1 - 3.9e-32 111.4 24.1 6.2e-32 110.8 24.1 1.3 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EKX41331.1 - 3.1e-06 26.1 13.1 3.1e-06 26.1 13.1 2.0 1 1 1 2 2 2 1 Polycystin cation channel PH PF00169.29 EKX41331.1 - 4.7e-05 23.8 0.0 0.00011 22.7 0.0 1.6 1 0 0 1 1 1 1 PH domain DUF4795 PF16043.5 EKX41331.1 - 0.2 11.2 1.9 0.44 10.1 1.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) RCC1_2 PF13540.6 EKX41332.1 - 4.4e-53 176.1 31.8 4.8e-12 45.3 0.1 5.2 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EKX41332.1 - 1.9e-47 159.6 21.7 9.9e-12 45.3 0.2 7.1 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 EKX41332.1 - 0.00017 22.1 1.3 12 6.3 0.0 4.4 3 2 2 5 5 5 2 SUKH-3 immunity protein Kelch_6 PF13964.6 EKX41332.1 - 0.0014 18.8 3.0 1.7 9.1 0.0 4.8 6 0 0 6 6 6 1 Kelch motif Ribosomal_L10 PF00466.20 EKX41333.1 - 0.13 12.4 0.1 0.31 11.2 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L10 Ribosomal_L14 PF00238.19 EKX41335.1 - 5.8e-35 120.0 0.2 7e-35 119.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PAAR_motif PF05488.13 EKX41335.1 - 0.037 14.2 0.1 0.083 13.1 0.1 1.7 1 0 0 1 1 1 0 PAAR motif RCC1 PF00415.18 EKX41336.1 - 3.4e-30 104.4 9.4 6.2e-11 42.7 0.0 4.1 3 1 1 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX41336.1 - 4.5e-12 45.4 21.4 4.2e-08 32.8 0.1 4.1 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat PapC_C PF13953.6 EKX41336.1 - 0.099 12.5 0.6 9 6.2 0.0 3.0 3 0 0 3 3 3 0 PapC C-terminal domain Ank PF00023.30 EKX41337.1 - 7.9e-11 41.9 0.2 3.2e-05 24.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EKX41337.1 - 1.9e-09 37.9 0.0 3.8e-07 30.5 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX41337.1 - 1.1e-08 35.2 0.0 3.6e-05 24.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX41337.1 - 4.7e-08 33.5 0.0 1.3e-07 32.1 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX41337.1 - 6e-07 29.3 0.5 0.00015 21.9 0.0 3.0 3 1 0 3 3 3 1 Ankyrin repeat RRM_1 PF00076.22 EKX41338.1 - 7.9e-16 57.7 0.1 1.1e-15 57.2 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRE_C2HC PF07530.11 EKX41338.1 - 0.089 12.9 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Associated with zinc fingers Limkain-b1 PF11608.8 EKX41338.1 - 0.094 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 RRM_occluded PF16842.5 EKX41338.1 - 0.24 11.3 0.0 0.39 10.6 0.0 1.3 1 1 0 1 1 1 0 Occluded RNA-recognition motif PDZ_6 PF17820.1 EKX41339.1 - 2.4e-06 27.3 0.1 6e-06 26.0 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX41339.1 - 7.1e-06 26.3 0.0 1.7e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX41339.1 - 0.00095 19.4 0.0 0.0026 18.0 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Prominin PF05478.11 EKX41339.1 - 0.0088 14.1 3.9 0.019 13.0 3.9 1.5 1 0 0 1 1 1 1 Prominin LMWPc PF01451.21 EKX41339.1 - 0.038 14.4 1.6 0.062 13.7 0.4 2.0 2 0 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase NPL PF17800.1 EKX41339.1 - 1 10.0 0.0 1 10.0 0.0 2.4 2 1 0 2 2 2 0 Nucleoplasmin-like domain AKNA PF12443.8 EKX41339.1 - 2.5 8.8 10.9 1.4 9.6 2.8 2.9 2 1 0 2 2 2 0 AT-hook-containing transcription factor DivIC PF04977.15 EKX41339.1 - 9.3 6.1 18.5 2.5 7.9 3.1 3.7 2 1 1 3 3 3 0 Septum formation initiator MORN PF02493.20 EKX41340.1 - 4.9e-50 164.5 49.6 2.2e-08 33.5 2.4 9.0 9 0 0 9 9 9 9 MORN repeat Peptidase_S55 PF05580.12 EKX41340.1 - 0.00019 21.4 5.9 2.1 8.3 0.1 4.5 1 1 3 5 5 5 3 SpoIVB peptidase S55 Mito_carr PF00153.27 EKX41341.1 - 1.2e-27 95.6 2.1 1.6e-08 34.3 0.0 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein Acyltransferase PF01553.21 EKX41344.1 - 4.3e-10 39.3 0.0 7.1e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Ank_2 PF12796.7 EKX41345.1 - 1.1e-26 93.2 2.2 4e-15 56.2 0.4 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX41345.1 - 4.5e-19 66.5 0.2 9.5e-05 22.5 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EKX41345.1 - 5.4e-19 68.3 2.1 6.7e-09 36.1 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX41345.1 - 4.2e-17 61.8 0.4 0.00016 22.0 0.1 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EKX41345.1 - 3.6e-16 59.0 2.0 4.6e-09 36.4 0.1 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) TPR_12 PF13424.6 EKX41346.1 - 4.9e-25 87.6 8.5 1.9e-08 34.4 0.0 7.1 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 EKX41346.1 - 4.3e-12 45.3 16.5 0.039 13.8 0.0 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 EKX41346.1 - 7.6e-12 44.7 10.5 6.2e-07 29.1 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX41346.1 - 1.1e-08 34.5 16.1 0.3 11.3 0.0 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX41346.1 - 1.6e-08 34.1 11.6 0.073 13.3 0.1 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX41346.1 - 3.7e-05 23.3 8.0 0.77 9.5 0.1 5.6 5 0 0 5 5 5 3 TPR repeat Caldesmon PF02029.15 EKX41346.1 - 0.0001 21.3 29.7 0.00012 21.0 29.7 1.2 1 0 0 1 1 1 1 Caldesmon LTV PF04180.14 EKX41347.1 - 7.6e-07 29.2 19.0 7.6e-07 29.2 19.0 6.0 1 1 3 5 5 5 2 Low temperature viability protein DUF2630 PF10944.8 EKX41347.1 - 3.5 8.1 16.3 1.4 9.5 5.8 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) DUF4629 PF15442.6 EKX41347.1 - 4.7 7.4 13.3 5 7.4 9.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4629) CENP-F_leu_zip PF10473.9 EKX41348.1 - 0.00042 20.4 1.0 0.0007 19.6 1.0 1.4 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HAP1_N PF04849.13 EKX41348.1 - 0.0033 16.7 0.1 0.0038 16.5 0.1 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region GIT_CC PF16559.5 EKX41348.1 - 0.0075 16.1 0.1 0.011 15.6 0.1 1.3 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.21 EKX41348.1 - 0.02 15.0 0.2 0.032 14.3 0.2 1.3 1 0 0 1 1 1 0 bZIP transcription factor LXG PF04740.12 EKX41348.1 - 0.047 13.4 0.0 0.061 13.0 0.0 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily DivIC PF04977.15 EKX41348.1 - 0.048 13.4 0.0 0.077 12.8 0.0 1.3 1 0 0 1 1 1 0 Septum formation initiator Pox_A_type_inc PF04508.12 EKX41348.1 - 0.12 12.3 3.0 6.1 6.9 1.4 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat PspB PF06667.12 EKX41348.1 - 0.13 12.3 0.1 0.26 11.4 0.1 1.5 1 0 0 1 1 1 0 Phage shock protein B LapA_dom PF06305.11 EKX41348.1 - 1.1 9.1 3.7 13 5.6 0.7 2.5 2 1 1 3 3 3 0 Lipopolysaccharide assembly protein A domain TPR_12 PF13424.6 EKX41349.1 - 1.9e-18 66.5 8.7 5e-09 36.3 1.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX41349.1 - 2e-16 59.0 12.0 3.7e-05 23.3 0.5 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX41349.1 - 1.8e-14 53.0 5.1 1.8e-05 24.4 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX41349.1 - 9.7e-13 47.2 9.8 0.0044 17.0 0.4 4.6 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX41349.1 - 3e-09 36.3 6.7 0.00052 20.0 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX41349.1 - 3.6e-07 29.7 5.5 0.05 13.7 0.1 4.6 5 1 0 5 5 5 2 Tetratricopeptide repeat DUF3856 PF12968.7 EKX41349.1 - 0.00011 22.3 2.5 0.0029 17.7 0.3 2.6 1 1 1 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_17 PF13431.6 EKX41349.1 - 0.00029 21.0 0.8 1 9.9 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.18 EKX41349.1 - 0.00071 19.6 8.3 0.016 15.2 0.2 4.1 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_14 PF13428.6 EKX41349.1 - 0.0011 19.6 4.7 2.8 9.0 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX41349.1 - 0.0018 17.7 3.5 0.045 13.1 0.2 2.9 1 1 1 3 3 3 1 MalT-like TPR region GATase_5 PF13507.6 EKX41349.1 - 0.0061 15.7 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain TPR_11 PF13414.6 EKX41349.1 - 0.013 15.1 5.4 1.5 8.6 0.0 3.7 4 0 0 4 4 4 0 TPR repeat PPR PF01535.20 EKX41349.1 - 0.02 15.1 0.4 14 6.2 0.0 3.5 3 0 0 3 3 3 0 PPR repeat DUF5113 PF17140.4 EKX41349.1 - 0.035 13.9 1.3 1.5 8.6 0.0 3.3 3 1 0 4 4 4 0 Domain of unknown function (DUF5113) ANAPC5 PF12862.7 EKX41349.1 - 0.098 12.7 2.7 1.1 9.4 2.7 2.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 5 Vps39_1 PF10366.9 EKX41349.1 - 0.13 12.6 1.2 1.6 9.0 0.1 2.4 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 1 TPR_4 PF07721.14 EKX41349.1 - 0.75 10.6 7.2 2.7 8.9 0.8 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX41349.1 - 0.79 10.5 5.5 32 5.5 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX41349.1 - 2.2 8.9 10.4 3.8 8.1 0.2 3.7 2 2 1 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.32 EKX41350.1 - 5.2e-42 141.0 29.2 1.8e-07 31.7 0.1 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX41350.1 - 6.5e-20 71.2 2.6 0.00077 19.7 0.3 6.2 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EKX41350.1 - 7e-06 26.1 3.3 0.13 12.1 0.3 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EKX41350.1 - 0.0013 18.2 0.0 0.086 12.1 0.0 2.5 1 1 1 2 2 2 1 WD40-like domain Methyltransf_22 PF13383.6 EKX41350.1 - 0.0019 17.8 0.7 0.0037 16.9 0.7 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cytochrom_D1 PF02239.16 EKX41350.1 - 0.024 13.2 0.0 0.069 11.7 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain BRD4_CDT PF17105.5 EKX41351.1 - 0.032 13.8 0.3 0.032 13.8 0.3 2.0 2 0 0 2 2 2 0 C-terminal domain of bromodomain protein 4 Ead_Ea22 PF13935.6 EKX41352.1 - 0.0097 16.6 0.0 0.011 16.4 0.0 1.2 1 0 0 1 1 1 1 Ead/Ea22-like protein KdpD PF02702.17 EKX41352.1 - 0.051 13.1 0.1 0.084 12.3 0.1 1.3 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain ATP-sulfurylase PF01747.17 EKX41352.1 - 0.056 12.9 0.1 0.073 12.5 0.1 1.2 1 0 0 1 1 1 0 ATP-sulfurylase AAA_35 PF14516.6 EKX41352.1 - 0.096 11.5 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain EF-hand_7 PF13499.6 EKX41354.1 - 0.00012 22.4 0.1 0.00035 21.0 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair Sensor_TM1 PF13755.6 EKX41354.1 - 0.035 13.8 0.4 0.08 12.7 0.4 1.5 1 0 0 1 1 1 0 Sensor N-terminal transmembrane domain EF-hand_1 PF00036.32 EKX41354.1 - 0.064 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 EF hand Macoilin PF09726.9 EKX41355.1 - 0.00032 19.4 5.3 0.00032 19.4 5.3 2.1 2 0 0 2 2 2 2 Macoilin family ABC_tran PF00005.27 EKX41356.1 - 3.7e-43 147.3 0.3 8.2e-22 78.2 0.0 3.8 4 1 0 4 4 3 2 ABC transporter AAA_21 PF13304.6 EKX41356.1 - 6.2e-11 42.6 3.5 0.028 14.2 0.1 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EKX41356.1 - 3.4e-07 29.9 0.6 0.0026 17.2 0.0 4.2 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EKX41356.1 - 3.8e-07 29.8 0.0 0.0049 16.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.12 EKX41356.1 - 5.2e-07 29.7 0.1 0.021 14.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA PF00004.29 EKX41356.1 - 0.00031 21.2 0.4 0.083 13.3 0.0 3.6 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EKX41356.1 - 0.00033 20.5 0.1 0.16 11.7 0.0 2.7 3 0 0 3 3 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EKX41356.1 - 0.00036 20.5 0.1 0.19 11.6 0.0 2.8 2 0 0 2 2 2 1 RsgA GTPase AAA_5 PF07728.14 EKX41356.1 - 0.0004 20.4 0.6 0.06 13.3 0.1 3.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EKX41356.1 - 0.00041 20.6 1.7 0.076 13.3 0.1 3.4 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EKX41356.1 - 0.001 19.5 3.3 0.043 14.2 0.0 3.3 4 0 0 4 4 2 1 AAA ATPase domain Roc PF08477.13 EKX41356.1 - 0.0015 18.7 0.0 0.082 13.1 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EKX41356.1 - 0.0016 18.5 0.0 2.9 8.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EKX41356.1 - 0.0025 18.3 6.5 1.8 9.0 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_24 PF13479.6 EKX41356.1 - 0.0043 16.8 0.1 0.11 12.3 0.0 2.8 2 1 1 3 3 3 1 AAA domain RNA_helicase PF00910.22 EKX41356.1 - 0.0069 16.8 0.0 0.55 10.6 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 EKX41356.1 - 0.0091 15.5 0.1 0.05 13.1 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region ABC_tran_Xtn PF12848.7 EKX41356.1 - 0.0092 16.0 5.6 0.0092 16.0 5.6 2.6 2 0 0 2 2 2 1 ABC transporter TsaE PF02367.17 EKX41356.1 - 0.011 15.7 0.0 0.23 11.5 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 EKX41356.1 - 0.015 15.2 0.1 0.48 10.3 0.1 2.6 2 0 0 2 2 2 0 NTPase DUF87 PF01935.17 EKX41356.1 - 0.019 15.1 5.8 0.63 10.1 0.0 3.5 3 0 0 3 3 3 0 Helicase HerA, central domain Mg_chelatase PF01078.21 EKX41356.1 - 0.051 12.9 2.4 0.74 9.2 0.0 3.2 3 1 0 4 4 3 0 Magnesium chelatase, subunit ChlI SbcCD_C PF13558.6 EKX41356.1 - 0.057 13.7 0.3 15 5.9 0.1 3.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 EKX41356.1 - 0.061 12.5 0.1 8.9 5.4 0.0 2.9 4 0 0 4 4 4 0 NB-ARC domain ATP-synt_ab PF00006.25 EKX41356.1 - 0.096 12.3 0.0 15 5.1 0.0 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RuvB_N PF05496.12 EKX41356.1 - 0.11 12.3 0.0 3.6 7.3 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain PduV-EutP PF10662.9 EKX41356.1 - 0.16 11.7 0.2 2 8.1 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 EKX41356.1 - 0.2 11.2 3.4 7.4 6.1 0.0 3.5 4 0 0 4 4 4 0 AAA domain AAA_18 PF13238.6 EKX41356.1 - 0.32 11.5 7.3 0.37 11.4 0.1 3.5 3 1 0 3 3 2 0 AAA domain AAA_28 PF13521.6 EKX41356.1 - 1.2 9.4 10.2 3.5 7.8 0.0 4.1 5 0 0 5 5 3 0 AAA domain TT_ORF1 PF02956.14 EKX41356.1 - 2 7.0 6.8 2.9 6.5 6.8 1.1 1 0 0 1 1 1 0 TT viral orf 1 CLP1_P PF16575.5 EKX41356.1 - 7.1 6.4 5.8 3.7 7.3 0.0 2.8 3 0 0 3 3 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 EKX41356.1 - 7.6 6.7 8.1 11 6.1 0.0 3.7 4 0 0 4 4 4 0 AAA domain Nucleotid_trans PF03407.16 EKX41357.1 - 3.1e-27 96.0 0.4 4.1e-27 95.5 0.4 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase PA PF02225.22 EKX41358.1 - 0.00045 20.2 0.0 0.00087 19.3 0.0 1.4 1 0 0 1 1 1 1 PA domain Prefoldin_2 PF01920.20 EKX41358.1 - 0.012 15.5 5.0 0.78 9.7 0.2 3.2 2 1 0 2 2 2 0 Prefoldin subunit BLOC1_2 PF10046.9 EKX41358.1 - 0.13 12.6 6.2 0.22 11.8 2.7 2.8 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.12 EKX41358.1 - 0.36 10.8 3.6 0.93 9.5 3.6 1.8 1 0 0 1 1 1 0 Laminin Domain II HEAT_2 PF13646.6 EKX41359.1 - 1.5e-06 28.5 12.7 0.0075 16.6 0.9 5.1 3 2 3 6 6 6 2 HEAT repeats HEAT PF02985.22 EKX41359.1 - 3.9e-06 26.7 3.8 0.4 11.1 0.0 5.4 6 0 0 6 6 6 2 HEAT repeat Keratin_2_head PF16208.5 EKX41359.1 - 0.0043 17.2 20.8 0.0095 16.1 20.8 1.5 1 0 0 1 1 1 1 Keratin type II head SRCR PF00530.18 EKX41359.1 - 0.045 14.3 0.1 0.13 12.8 0.1 1.8 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain TAF6_C PF07571.13 EKX41359.1 - 3.9 7.9 5.9 8.1 6.8 0.2 3.4 4 0 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain Tctex-1 PF03645.13 EKX41360.1 - 2.7e-25 88.6 0.2 3e-25 88.4 0.2 1.0 1 0 0 1 1 1 1 Tctex-1 family GAF PF01590.26 EKX41362.1 - 3e-30 105.6 0.2 6e-12 46.3 0.0 3.5 3 0 0 3 3 3 3 GAF domain GAF_2 PF13185.6 EKX41362.1 - 7.1e-19 68.5 0.1 9.2e-06 26.0 0.0 3.7 3 0 0 3 3 3 3 GAF domain PAN_4 PF14295.6 EKX41363.1 - 2e-05 24.4 2.9 4e-05 23.4 2.9 1.5 1 0 0 1 1 1 1 PAN domain LrgB PF04172.16 EKX41364.1 - 0.067 12.7 0.3 0.081 12.4 0.3 1.1 1 0 0 1 1 1 0 LrgB-like family Collagen PF01391.18 EKX41365.1 - 0.00057 19.6 35.3 0.0019 17.9 7.5 2.8 3 0 0 3 3 3 2 Collagen triple helix repeat (20 copies) Aldo_ket_red PF00248.21 EKX41366.1 - 2.6e-63 214.0 0.0 2.9e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Radical_SAM PF04055.21 EKX41367.1 - 1e-10 42.3 0.0 1.5e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 EKX41367.1 - 6.3e-07 29.8 0.2 1.8e-06 28.3 0.2 1.8 1 1 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Glycos_transf_1 PF00534.20 EKX41368.1 - 1.2e-08 34.7 0.0 2.2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EKX41368.1 - 1.6e-08 35.1 0.0 3.6e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 PhyH PF05721.13 EKX41368.1 - 0.022 15.0 0.1 0.11 12.8 0.1 2.0 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) DUF1936 PF09151.10 EKX41368.1 - 3.2 7.8 6.2 0.57 10.1 1.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) SMI1_KNR4 PF09346.10 EKX41369.1 - 0.0054 17.1 0.2 0.024 15.0 0.2 1.9 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) CDRN PF05174.12 EKX41369.1 - 0.021 14.5 2.8 1.7 8.4 0.6 2.4 2 0 0 2 2 2 0 Cysteine-rich D. radiodurans N terminus DEC-1_N PF04625.13 EKX41370.1 - 0.24 10.4 1.6 0.33 9.9 1.6 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Pkinase PF00069.25 EKX41371.1 - 1.1e-25 90.5 0.0 1.1e-24 87.2 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX41371.1 - 4.1e-12 45.9 0.3 4e-11 42.7 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX41371.1 - 1.5e-05 24.4 0.7 3.2e-05 23.4 0.1 1.8 2 0 0 2 2 2 1 Kinase-like HAUS2 PF15003.6 EKX41371.1 - 0.064 13.0 2.9 0.068 12.9 0.7 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 2 DUF4484 PF14831.6 EKX41371.1 - 0.096 12.7 3.6 0.29 11.1 3.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Serine_rich PF08824.10 EKX41371.1 - 0.35 10.9 7.5 0.088 12.8 1.2 2.7 3 0 0 3 3 3 0 Serine rich protein interaction domain DUF883 PF05957.13 EKX41371.1 - 1 10.0 4.7 7.2 7.3 0.2 3.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) RPW8 PF05659.11 EKX41371.1 - 2.8 7.6 7.6 1.1 8.9 0.3 3.3 3 1 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 CTU2 PF10288.9 EKX41371.1 - 3 8.1 10.4 0.93 9.8 4.0 2.5 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF948 PF06103.11 EKX41371.1 - 6.5 7.1 5.2 49 4.3 0.4 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) MTS PF05175.14 EKX41372.1 - 7.8e-05 22.3 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EKX41372.1 - 8.9e-05 22.5 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX41372.1 - 0.00014 21.7 0.0 0.00023 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX41372.1 - 0.00071 20.2 0.0 0.0017 19.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX41372.1 - 0.0008 19.3 0.0 0.00096 19.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EKX41372.1 - 0.0013 18.8 0.0 0.0017 18.5 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase TRM13 PF05206.14 EKX41372.1 - 0.011 15.3 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 Methyltransf_12 PF08242.12 EKX41372.1 - 0.032 15.0 0.0 0.059 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 EKX41372.1 - 0.038 13.3 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 EKX41372.1 - 0.046 13.2 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_11 PF08241.12 EKX41372.1 - 0.056 14.1 0.0 0.14 12.8 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_2 PF00891.18 EKX41372.1 - 0.098 11.9 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_18 PF12847.7 EKX41372.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GCD14 PF08704.10 EKX41372.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_5 PF01795.19 EKX41372.1 - 0.2 11.1 0.0 0.28 10.7 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family Histone_HNS PF00816.21 EKX41373.1 - 5.2 8.0 11.2 19 6.1 3.8 3.1 2 1 1 3 3 3 0 H-NS histone family PDZ_6 PF17820.1 EKX41374.1 - 4.9e-19 67.9 0.4 1.1e-09 38.0 0.1 2.6 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 EKX41374.1 - 2e-17 63.3 1.6 4.3e-11 43.0 0.2 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX41374.1 - 7.2e-17 61.5 1.1 5.8e-10 39.4 0.0 2.9 3 0 0 3 3 2 2 PDZ domain Tricorn_PDZ PF14685.6 EKX41374.1 - 1.3e-06 28.3 0.2 0.0017 18.3 0.1 2.8 2 0 0 2 2 2 1 Tricorn protease PDZ domain DUF1664 PF07889.12 EKX41374.1 - 0.00015 21.8 8.2 0.0099 15.9 0.7 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 EKX41374.1 - 0.00016 21.9 21.3 0.00016 21.9 21.3 3.3 2 1 2 4 4 4 1 Tropomyosin like GRASP55_65 PF04495.14 EKX41374.1 - 0.00032 21.0 0.0 0.21 11.9 0.0 2.4 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain DUF2968 PF11180.8 EKX41374.1 - 0.00099 18.8 16.2 0.0025 17.4 11.5 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2968) HAUS-augmin3 PF14932.6 EKX41374.1 - 0.0011 18.6 15.0 0.0011 18.6 15.0 3.0 2 2 1 3 3 3 1 HAUS augmin-like complex subunit 3 DUF641 PF04859.12 EKX41374.1 - 0.0014 19.0 4.6 0.0014 19.0 4.6 3.1 2 1 1 3 3 3 1 Plant protein of unknown function (DUF641) HMMR_N PF15905.5 EKX41374.1 - 0.0015 18.1 20.9 0.0015 18.1 20.9 1.7 2 0 0 2 2 2 1 Hyaluronan mediated motility receptor N-terminal PI3K_P85_iSH2 PF16454.5 EKX41374.1 - 0.0015 18.2 21.3 0.053 13.1 3.3 3.6 2 1 2 4 4 3 2 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SHE3 PF17078.5 EKX41374.1 - 0.0047 16.7 11.1 0.0072 16.1 10.2 1.7 1 1 0 1 1 1 1 SWI5-dependent HO expression protein 3 Tropomyosin PF00261.20 EKX41374.1 - 0.011 15.1 39.1 0.082 12.3 20.4 3.3 2 1 1 3 3 3 0 Tropomyosin Biotin_lipoyl_2 PF13533.6 EKX41374.1 - 0.012 15.4 1.1 0.51 10.2 0.1 2.9 2 0 0 2 2 2 0 Biotin-lipoyl like GAS PF13851.6 EKX41374.1 - 0.017 14.5 21.8 0.057 12.8 21.8 1.8 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding EzrA PF06160.12 EKX41374.1 - 0.027 12.7 15.4 0.13 10.5 11.7 2.4 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Laminin_II PF06009.12 EKX41374.1 - 0.028 14.4 12.8 6.3 6.8 7.8 3.7 1 1 2 3 3 3 0 Laminin Domain II IFT57 PF10498.9 EKX41374.1 - 0.091 11.7 14.7 0.32 9.9 14.7 1.9 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Baculo_PEP_C PF04513.12 EKX41374.1 - 0.13 12.3 2.5 1.8 8.6 0.1 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.6 EKX41374.1 - 0.13 10.9 15.6 0.37 9.4 15.6 1.8 1 1 0 1 1 1 0 AAA domain DUF4407 PF14362.6 EKX41374.1 - 0.18 11.1 21.6 0.039 13.3 17.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF3584 PF12128.8 EKX41374.1 - 0.25 8.8 23.6 0.0076 13.8 17.2 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) Troponin PF00992.20 EKX41374.1 - 0.28 11.5 22.5 0.34 11.2 7.7 3.3 1 1 2 3 3 3 0 Troponin PIN_12 PF16289.5 EKX41374.1 - 0.47 10.9 3.0 0.99 9.9 3.0 1.6 1 0 0 1 1 1 0 PIN domain T3SSipB PF16535.5 EKX41374.1 - 0.74 10.3 14.7 1.6 9.2 13.8 2.1 1 1 0 1 1 1 0 Type III cell invasion protein SipB IFT20 PF14931.6 EKX41374.1 - 0.75 10.0 16.8 16 5.7 13.9 3.2 2 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 FlxA PF14282.6 EKX41374.1 - 1 9.4 10.6 2 8.4 7.3 2.6 1 1 1 2 2 2 0 FlxA-like protein Fib_alpha PF08702.10 EKX41374.1 - 1.1 9.4 6.2 3.5 7.8 5.5 2.2 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 EKX41374.1 - 1.3 9.5 43.4 0.029 14.9 18.1 3.9 2 2 1 3 3 2 0 Apg6 coiled-coil region DUF16 PF01519.16 EKX41374.1 - 1.5 9.4 13.9 5.6 7.5 1.0 3.5 2 1 1 3 3 3 0 Protein of unknown function DUF16 Spc7 PF08317.11 EKX41374.1 - 1.6 7.5 34.0 0.017 14.0 11.8 2.6 2 1 1 3 3 3 0 Spc7 kinetochore protein Fzo_mitofusin PF04799.13 EKX41374.1 - 1.7 8.2 12.3 3.6 7.1 3.6 3.0 1 1 2 3 3 3 0 fzo-like conserved region Prominin PF05478.11 EKX41374.1 - 1.8 6.4 5.1 2.8 5.8 5.1 1.4 1 0 0 1 1 1 0 Prominin FOXP-CC PF16159.5 EKX41374.1 - 1.8 9.2 9.2 0.21 12.2 1.0 3.4 3 1 1 4 4 2 0 FOXP coiled-coil domain OmpH PF03938.14 EKX41374.1 - 2 8.7 24.2 29 5.0 18.7 3.0 2 1 0 2 2 1 0 Outer membrane protein (OmpH-like) HrpB7 PF09486.10 EKX41374.1 - 2.1 8.7 24.1 3.6 7.9 9.4 2.8 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Bacillus_HBL PF05791.11 EKX41374.1 - 2.4 8.0 6.7 4.6 7.0 5.3 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) MbeD_MobD PF04899.12 EKX41374.1 - 2.4 8.3 7.1 15 5.8 1.5 3.3 2 1 0 2 2 2 0 MbeD/MobD like DUF3450 PF11932.8 EKX41374.1 - 2.6 7.3 16.6 1.3 8.2 8.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.12 EKX41374.1 - 2.7 8.1 36.5 0.1 12.7 2.2 3.6 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein FPP PF05911.11 EKX41374.1 - 2.8 6.0 32.8 1.7 6.8 23.1 3.0 2 1 1 3 3 3 0 Filament-like plant protein, long coiled-coil Cast PF10174.9 EKX41374.1 - 2.8 6.0 24.9 0.053 11.8 18.1 1.5 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone Prefoldin_2 PF01920.20 EKX41374.1 - 3 7.9 26.3 0.73 9.8 4.0 4.8 2 1 3 5 5 4 0 Prefoldin subunit Muted PF14942.6 EKX41374.1 - 3.4 8.0 22.3 0.095 13.0 6.6 3.0 2 1 1 3 3 2 0 Organelle biogenesis, Muted-like protein TMF_DNA_bd PF12329.8 EKX41374.1 - 3.5 7.7 36.5 0.059 13.4 18.3 4.4 3 2 1 4 4 4 0 TATA element modulatory factor 1 DNA binding FH2 PF02181.23 EKX41374.1 - 4.7 6.2 15.9 3.2 6.8 10.1 2.5 1 1 1 2 2 2 0 Formin Homology 2 Domain HemX PF04375.14 EKX41374.1 - 4.8 6.4 21.8 0.18 11.1 6.5 2.5 2 1 1 3 3 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase P4Ha_N PF08336.11 EKX41374.1 - 5 7.1 12.3 2.1 8.4 2.6 2.9 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region FlaC_arch PF05377.11 EKX41374.1 - 5.8 7.4 11.3 27 5.2 0.0 4.4 4 1 1 5 5 3 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 EKX41374.1 - 6.4 6.8 29.2 2.2 8.4 10.0 3.1 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF812 PF05667.11 EKX41374.1 - 6.8 5.5 25.1 1.2 7.9 20.9 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF812) TMF_TATA_bd PF12325.8 EKX41374.1 - 7.4 6.8 30.0 0.41 10.9 8.3 4.0 2 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Sec34 PF04136.15 EKX41374.1 - 7.6 6.4 14.8 3.4 7.5 3.1 3.4 1 1 2 3 3 3 0 Sec34-like family BLOC1_2 PF10046.9 EKX41374.1 - 7.9 6.9 19.2 1.9 8.9 7.1 3.9 3 1 2 5 5 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spectrin PF00435.21 EKX41374.1 - 7.9 7.0 25.6 0.24 11.9 13.1 3.3 2 2 0 3 3 2 0 Spectrin repeat DUF948 PF06103.11 EKX41374.1 - 9.8 6.5 7.3 22 5.4 0.6 3.7 2 1 2 4 4 3 0 Bacterial protein of unknown function (DUF948) zf-CCCH PF00642.24 EKX41376.1 - 6.1e-05 22.8 8.3 6.6e-05 22.7 0.5 3.0 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EKX41376.1 - 0.0057 16.7 0.7 0.0057 16.7 0.7 3.5 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_4 PF18044.1 EKX41376.1 - 0.01 15.6 1.1 0.01 15.6 1.1 3.0 3 0 0 3 3 3 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EKX41376.1 - 0.018 15.5 0.7 0.018 15.5 0.7 3.4 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Metallothio_PEC PF02068.16 EKX41376.1 - 0.8 10.1 7.1 3.2 8.2 7.1 1.8 1 1 0 1 1 1 0 Plant PEC family metallothionein a_DG1_N2 PF18424.1 EKX41377.1 - 0.17 11.9 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 Alpha-Dystroglycan N-terminal domain 2 Ephrin_rec_like PF07699.13 EKX41377.1 - 3.7 7.4 13.0 2.8e+02 1.4 11.3 3.3 2 1 0 2 2 2 0 Putative ephrin-receptor like Dickkopf_N PF04706.12 EKX41377.1 - 4.7 7.8 9.7 0.64 10.5 3.9 2.6 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Kelch_5 PF13854.6 EKX41378.1 - 6.6e-18 64.3 0.0 0.0011 19.0 0.0 5.5 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 EKX41378.1 - 4.6e-17 61.8 1.1 4.3e-06 26.6 0.0 6.0 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 EKX41378.1 - 5e-12 45.3 0.3 1.4e-05 24.9 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 EKX41378.1 - 2.4e-11 43.5 0.1 2.3e-05 24.5 0.0 4.4 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 EKX41378.1 - 1.8e-09 37.0 2.7 0.00019 20.9 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 EKX41378.1 - 5e-09 36.2 9.3 0.0026 18.0 0.0 6.9 7 2 0 7 7 7 2 Galactose oxidase, central domain RAG2 PF03089.14 EKX41378.1 - 0.0075 15.3 0.0 2.6 6.9 0.0 3.5 4 0 0 4 4 4 1 Recombination activating protein 2 HAD PF12710.7 EKX41379.1 - 0.051 14.0 0.1 0.2 12.1 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DDHD PF02862.17 EKX41379.1 - 0.73 9.9 12.6 0.24 11.5 4.2 3.1 3 0 0 3 3 3 0 DDHD domain SDA1 PF05285.12 EKX41379.1 - 0.94 8.8 45.6 1 8.7 35.0 3.3 3 0 0 3 3 3 0 SDA1 Pkinase PF00069.25 EKX41380.1 - 5.7e-52 176.7 0.0 7.1e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX41380.1 - 3.5e-31 108.4 0.0 4.1e-31 108.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX41380.1 - 1.3e-05 24.6 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EKX41380.1 - 0.0003 20.8 0.2 0.0048 16.8 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX41380.1 - 0.014 14.7 0.0 0.023 14.1 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EKX41380.1 - 0.035 13.2 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Vps51 PF08700.11 EKX41380.1 - 0.072 13.2 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 Vps51/Vps67 FTA2 PF13095.6 EKX41380.1 - 0.11 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 PAN_4 PF14295.6 EKX41382.1 - 1.1e-05 25.2 3.5 2.1e-05 24.3 3.5 1.5 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 EKX41382.1 - 0.00015 21.6 0.6 0.00038 20.4 0.6 1.6 1 0 0 1 1 1 1 PAN domain Nucleotid_trans PF03407.16 EKX41382.1 - 0.00023 21.2 0.0 0.00042 20.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase GNT-I PF03071.15 EKX41382.1 - 0.056 12.2 0.1 0.59 8.8 0.0 2.1 2 0 0 2 2 2 0 GNT-I family Abhydrolase_6 PF12697.7 EKX41383.1 - 0.032 14.8 0.7 0.046 14.3 0.7 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family fn3 PF00041.21 EKX41385.1 - 7.5e-35 119.1 9.6 1.1e-08 35.3 0.0 7.8 8 0 0 8 8 8 5 Fibronectin type III domain SRCR PF00530.18 EKX41385.1 - 1.4e-11 44.7 13.4 1.5e-07 31.9 0.7 3.4 3 0 0 3 3 3 2 Scavenger receptor cysteine-rich domain DUF4215 PF13948.6 EKX41385.1 - 7e-05 23.2 3.5 0.00026 21.3 3.5 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4215) Tissue_fac PF01108.17 EKX41385.1 - 8.2e-05 22.4 0.0 5.3 6.9 0.0 4.1 3 0 0 3 3 3 2 Tissue factor PH PF00169.29 EKX41385.1 - 0.0021 18.6 0.0 0.0061 17.1 0.0 1.9 1 0 0 1 1 1 1 PH domain C2 PF00168.30 EKX41385.1 - 0.0027 18.0 0.0 0.0087 16.3 0.0 1.8 2 0 0 2 2 2 1 C2 domain BNR PF02012.20 EKX41385.1 - 0.0044 16.8 3.9 1.9 8.8 2.0 3.2 2 0 0 2 2 2 2 BNR/Asp-box repeat CHB_HEX_C PF03174.13 EKX41385.1 - 0.021 14.8 0.4 4.4 7.4 0.0 2.6 2 0 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain PAN_3 PF08277.12 EKX41385.1 - 0.12 12.2 1.9 0.39 10.6 1.9 1.9 1 0 0 1 1 1 0 PAN-like domain DEAD PF00270.29 EKX41387.1 - 7.6e-47 159.3 0.0 3.9e-46 157.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX41387.1 - 1.2e-30 106.1 0.0 3.1e-30 104.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX41387.1 - 0.00012 22.1 0.3 0.0011 18.9 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Atrophin-1 PF03154.15 EKX41387.1 - 6.6 4.9 15.0 12 4.0 15.0 1.3 1 0 0 1 1 1 0 Atrophin-1 family Kelch_4 PF13418.6 EKX41389.1 - 8.4e-37 125.0 0.1 7.6e-12 45.1 0.0 6.1 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EKX41389.1 - 3.3e-33 113.3 1.2 1.5e-06 28.3 0.0 7.1 6 1 1 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.25 EKX41389.1 - 4.6e-30 103.0 0.0 3.9e-11 42.3 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 EKX41389.1 - 2.7e-23 81.4 0.0 1.2e-07 31.7 0.0 6.2 5 1 1 6 6 6 3 Kelch motif Kelch_5 PF13854.6 EKX41389.1 - 1.4e-22 79.2 0.1 2.2e-06 27.5 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 EKX41389.1 - 4.8e-18 64.4 0.0 5.3e-06 26.2 0.1 5.7 5 0 0 5 5 5 4 Kelch motif MORN PF02493.20 EKX41390.1 - 1.4e-07 31.0 18.7 1.5e-06 27.8 1.0 4.2 4 0 0 4 4 4 3 MORN repeat BTB PF00651.31 EKX41392.1 - 8.8e-24 83.9 0.5 2.8e-22 79.0 0.3 2.0 1 1 1 2 2 2 2 BTB/POZ domain VirC1 PF07015.11 EKX41392.1 - 0.1 11.8 0.0 0.13 11.5 0.0 1.2 1 1 0 1 1 1 0 VirC1 protein Glyco_transf_8 PF01501.20 EKX41393.1 - 3.1e-17 63.0 0.3 1.9e-12 47.3 0.0 2.6 1 1 1 2 2 2 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EKX41393.1 - 0.0021 17.5 0.1 0.0027 17.1 0.1 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_24 PF18404.1 EKX41393.1 - 0.019 14.4 0.0 0.068 12.6 0.1 1.7 2 0 0 2 2 2 0 Glucosyltransferase 24 Glyco_hydro_79n PF03662.14 EKX41394.1 - 2.6e-27 95.6 0.0 3.8e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 79, N-terminal domain Guanylate_cyc PF00211.20 EKX41395.1 - 7.4e-20 71.3 0.7 1.4e-09 37.8 0.2 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 EKX41395.1 - 2.3e-09 37.8 0.0 8.9e-09 35.9 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EKX41395.1 - 0.0016 18.3 0.3 1.3 9.0 0.1 2.6 2 0 0 2 2 2 2 NACHT domain Hpt PF01627.23 EKX41395.1 - 0.0019 18.4 0.4 0.0073 16.5 0.4 2.1 1 0 0 1 1 1 1 Hpt domain Mg_chelatase PF01078.21 EKX41395.1 - 0.12 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cornifin PF02389.15 EKX41397.1 - 0.042 14.1 0.0 0.046 13.9 0.0 1.1 1 0 0 1 1 1 0 Cornifin (SPRR) family DUF2283 PF10049.9 EKX41397.1 - 1.9 8.8 5.5 1.1e+02 3.1 0.3 3.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2283) HHH_3 PF12836.7 EKX41398.1 - 7.8e-08 32.5 0.0 1.6e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HEAT_2 PF13646.6 EKX41398.1 - 5.5e-05 23.5 0.6 0.21 12.0 0.0 4.0 3 0 0 3 3 3 1 HEAT repeats Arm PF00514.23 EKX41398.1 - 0.00015 21.7 0.2 1.2 9.3 0.2 4.6 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat DUF5588 PF17826.1 EKX41398.1 - 0.13 11.2 0.0 0.27 10.1 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5588) HEAT PF02985.22 EKX41398.1 - 2.3 8.7 8.7 1.1 9.7 0.1 4.0 4 0 0 4 4 4 0 HEAT repeat Ion_trans PF00520.31 EKX41400.1 - 1.9e-46 158.3 43.6 1e-18 67.5 7.8 4.7 5 0 0 5 5 5 3 Ion transport protein RETICULATA-like PF11891.8 EKX41400.1 - 0.037 13.9 0.0 7.8 6.3 0.0 2.7 3 0 0 3 3 3 0 Protein RETICULATA-related GAF_2 PF13185.6 EKX41401.1 - 5.7e-06 26.7 0.0 1.4e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EKX41401.1 - 0.017 15.8 0.0 0.034 14.8 0.0 1.5 1 0 0 1 1 1 0 GAF domain PDT PF00800.18 EKX41403.1 - 5.9e-38 130.5 2.2 8.5e-36 123.5 0.6 2.5 1 1 1 2 2 2 2 Prephenate dehydratase ACT PF01842.25 EKX41403.1 - 1.2e-08 34.6 0.0 3e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 ACT domain Tymo_coat PF00983.18 EKX41403.1 - 0.0079 16.0 0.1 0.5 10.2 0.1 2.2 1 1 1 2 2 2 2 Tymovirus coat protein Put_Phosphatase PF06888.12 EKX41405.1 - 4.7e-43 147.3 0.0 5.8e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 EKX41405.1 - 1.4e-06 28.8 0.2 3e-06 27.8 0.2 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EKX41405.1 - 0.00039 20.6 2.0 2.8 8.0 3.0 3.3 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase MatE PF01554.18 EKX41405.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 MatE Amidinotransf PF02274.17 EKX41406.1 - 5.3e-15 55.3 0.0 7.1e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Amidinotransferase DUF1572 PF07609.11 EKX41407.1 - 0.11 12.3 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) BTV_NS2 PF04514.12 EKX41407.1 - 0.82 8.4 5.4 1.4 7.6 5.4 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FAM176 PF14851.6 EKX41407.1 - 3.5 7.3 9.9 0.74 9.5 1.6 3.0 2 1 1 3 3 3 0 FAM176 family Ank_2 PF12796.7 EKX41408.1 - 1.6e-06 28.6 0.0 2.7e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX41408.1 - 0.00097 19.4 0.0 0.0031 17.8 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX41408.1 - 0.0094 16.4 0.0 3.7 8.4 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EKX41408.1 - 0.017 15.5 0.0 1.2 9.7 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat TFIIA PF03153.13 EKX41409.1 - 0.59 10.1 21.8 0.79 9.6 21.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GldM_N PF12081.8 EKX41409.1 - 0.91 9.6 13.6 6.1 6.9 13.0 2.2 1 1 1 2 2 2 0 GldM N-terminal domain WDCP PF15390.6 EKX41409.1 - 1.9 6.8 17.6 2.5 6.4 17.6 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family He_PIG PF05345.12 EKX41410.1 - 1.5e-05 25.1 0.4 0.00034 20.7 0.2 2.7 2 0 0 2 2 2 1 Putative Ig domain I-set PF07679.16 EKX41410.1 - 0.057 13.5 0.0 11 6.2 0.0 3.3 3 0 0 3 3 3 0 Immunoglobulin I-set domain C2 PF00168.30 EKX41412.1 - 9.5e-09 35.5 0.0 2.2e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 C2 domain TMF_TATA_bd PF12325.8 EKX41412.1 - 0.0083 16.3 11.3 0.0083 16.3 11.3 5.0 1 1 4 5 5 5 2 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 EKX41412.1 - 1.1 9.3 63.8 0.21 11.6 10.8 3.6 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 EKX41412.1 - 5.3 7.4 56.9 0.3 11.5 22.8 3.1 1 1 2 3 3 3 0 Fez1 Prominin PF05478.11 EKX41412.1 - 6.1 4.7 18.3 2.7 5.8 15.4 1.7 1 1 1 2 2 2 0 Prominin Alanine_zipper PF11839.8 EKX41412.1 - 6.1 7.3 13.9 10 6.5 4.6 3.5 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein zf-SNAP50_C PF12251.8 EKX41413.1 - 4.9e-21 75.3 0.0 5.4e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal C1_1 PF00130.22 EKX41413.1 - 0.038 13.9 0.6 0.038 13.9 0.6 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ion_trans PF00520.31 EKX41414.1 - 1.1e-15 57.5 17.9 1.1e-15 57.5 17.9 1.6 1 1 1 2 2 2 1 Ion transport protein Trypsin PF00089.26 EKX41415.1 - 1.4e-22 80.7 0.0 1.9e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Trypsin RhaT PF06379.12 EKX41416.1 - 1.5e-09 37.5 9.1 1.5e-09 37.5 9.1 1.8 2 0 0 2 2 2 1 L-rhamnose-proton symport protein (RhaT) PH PF00169.29 EKX41416.1 - 0.00024 21.5 1.0 0.00047 20.6 1.0 1.5 1 0 0 1 1 1 1 PH domain DUF2244 PF10003.9 EKX41416.1 - 3.2 7.4 5.0 5 6.8 0.1 2.8 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) Glycos_transf_1 PF00534.20 EKX41417.1 - 7.3e-31 107.0 0.0 1.3e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EKX41417.1 - 7.8e-25 87.9 0.1 2.4e-24 86.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EKX41417.1 - 3.8e-07 30.4 1.4 7e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 FragX_IP PF05994.11 EKX41418.1 - 5.2e-130 435.0 0.0 8.7e-130 434.3 0.0 1.4 2 0 0 2 2 2 1 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 EKX41418.1 - 1.3e-06 27.9 0.9 2.6e-06 26.9 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) HeLo PF14479.6 EKX41418.1 - 0.015 15.2 0.0 0.043 13.6 0.0 1.8 1 0 0 1 1 1 0 Prion-inhibition and propagation RRM_1 PF00076.22 EKX41420.1 - 2.4e-12 46.5 0.0 0.0027 17.5 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.13 EKX41420.1 - 6.8e-08 32.6 0.0 1.3e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 SPOC domain RRM_occluded PF16842.5 EKX41420.1 - 0.044 13.6 0.0 16 5.4 0.0 3.0 2 0 0 2 2 2 0 Occluded RNA-recognition motif EGF_2 PF07974.13 EKX41424.1 - 2.3e-19 69.4 109.8 4e-06 27.1 7.3 7.6 7 0 0 7 7 7 7 EGF-like domain EGF PF00008.27 EKX41424.1 - 8e-08 32.5 85.8 0.052 13.9 7.0 7.8 7 0 0 7 7 7 6 EGF-like domain EGF_Tenascin PF18720.1 EKX41424.1 - 0.00031 20.7 87.4 0.04 14.0 9.7 7.8 7 1 0 7 7 7 6 Tenascin EGF domain hEGF PF12661.7 EKX41424.1 - 0.0078 16.8 86.2 0.0098 16.5 6.0 8.6 8 0 0 8 8 8 6 Human growth factor-like EGF Pkinase PF00069.25 EKX41425.1 - 1.8e-49 168.5 0.0 2.5e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX41425.1 - 5.4e-43 147.2 0.0 6.4e-43 146.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX41425.1 - 0.0097 15.9 0.1 0.02 14.8 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX41425.1 - 0.057 12.2 0.0 0.075 11.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase PhyH PF05721.13 EKX41426.1 - 3.4e-39 135.3 0.0 4.5e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 EKX41426.1 - 0.022 15.1 0.0 0.051 14.0 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DUF1279 PF06916.13 EKX41427.1 - 2.7e-10 40.6 0.1 5.8e-10 39.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DUF2833 PF11090.8 EKX41427.1 - 0.046 14.1 0.0 0.14 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2833) SRTM1 PF15872.5 EKX41427.1 - 0.085 13.0 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 PH PF00169.29 EKX41428.1 - 4.5e-06 27.1 1.0 9.2e-06 26.1 1.0 1.5 1 0 0 1 1 1 1 PH domain Pkinase PF00069.25 EKX41429.1 - 1.1e-46 159.4 0.0 1.4e-46 159.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX41429.1 - 5.1e-43 147.2 0.0 3.6e-42 144.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX41429.1 - 0.0026 17.7 0.0 0.0048 16.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX41429.1 - 0.15 10.8 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Ephrin_rec_like PF07699.13 EKX41432.1 - 1.3e-29 101.7 68.2 1.4e-09 37.5 9.6 6.0 5 1 1 6 6 6 4 Putative ephrin-receptor like EGF_2 PF07974.13 EKX41432.1 - 1.1e-07 32.1 20.0 0.27 11.6 0.5 5.7 4 0 0 4 4 4 4 EGF-like domain EGF_MSP1_1 PF12946.7 EKX41432.1 - 3.3e-05 23.8 23.1 0.0094 16.0 1.9 5.3 5 1 0 5 5 5 3 MSP1 EGF domain 1 EGF_3 PF12947.7 EKX41432.1 - 1.3 9.3 39.5 1.2 9.3 4.9 5.5 4 2 0 4 4 4 0 EGF domain cEGF PF12662.7 EKX41432.1 - 3.4 7.7 51.8 0.51 10.3 4.4 5.8 6 0 0 6 6 6 0 Complement Clr-like EGF-like Plasmod_Pvs28 PF06247.11 EKX41432.1 - 4.1 7.8 25.0 1.4 9.3 1.5 4.9 4 0 0 4 4 4 0 Pvs28 EGF domain Pkinase_Tyr PF07714.17 EKX41433.1 - 1.5e-60 204.7 0.0 1.6e-60 204.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX41433.1 - 1.2e-27 97.0 0.0 1.3e-27 96.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EKX41433.1 - 4.1e-05 23.0 0.0 6.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like TAFII28 PF04719.14 EKX41434.1 - 1.2e-19 70.1 0.0 2.3e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Cwf_Cwc_15 PF04889.12 EKX41434.1 - 0.019 14.7 20.9 0.025 14.3 20.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Mitofilin PF09731.9 EKX41434.1 - 4.4 6.0 21.0 5 5.8 21.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Ndc1_Nup PF09531.10 EKX41434.1 - 6.8 5.2 6.5 7.4 5.1 6.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup tRNA_U5-meth_tr PF05958.11 EKX41435.1 - 3e-06 26.5 0.0 2.5e-05 23.4 0.0 2.1 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Met_10 PF02475.16 EKX41435.1 - 0.0032 17.2 0.0 0.0062 16.3 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 EKX41435.1 - 0.0052 16.4 0.1 0.012 15.2 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical protein 95 MTS PF05175.14 EKX41435.1 - 0.026 14.0 0.0 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain VCBS PF13517.6 EKX41436.1 - 1.3e-22 80.1 0.5 1.2e-09 38.7 0.2 4.7 3 0 0 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EPTP PF03736.17 EKX41436.1 - 1.6e-12 47.2 1.6 0.0028 17.6 0.0 5.8 5 0 0 5 5 5 3 EPTP domain FG-GAP PF01839.23 EKX41436.1 - 7.2e-07 29.2 14.8 0.37 11.0 0.4 5.5 5 0 0 5 5 5 3 FG-GAP repeat BBS2_Mid PF14783.6 EKX41436.1 - 0.0055 16.7 0.0 77 3.4 0.0 4.8 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Velvet PF11754.8 EKX41436.1 - 0.17 11.8 0.8 20 5.0 0.0 4.4 5 0 0 5 5 5 0 Velvet factor Glyco_hydro2_C5 PF18565.1 EKX41436.1 - 0.35 10.7 7.0 36 4.3 0.1 6.3 6 0 0 6 6 6 0 Glycoside hydrolase family 2 C-terminal domain 5 Uteroglobin PF01099.17 EKX41437.1 - 0.14 12.5 0.6 0.57 10.6 0.4 2.1 1 1 1 2 2 2 0 Uteroglobin family tRNA_U5-meth_tr PF05958.11 EKX41438.1 - 3.6e-10 39.4 0.0 2e-09 36.9 0.0 2.0 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 EKX41438.1 - 8.6e-05 22.4 0.1 0.00013 21.8 0.1 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX41438.1 - 0.014 16.1 0.0 0.029 15.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EKX41438.1 - 0.032 14.9 0.0 0.072 13.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EKX41438.1 - 0.034 13.5 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) BT1 PF03092.16 EKX41442.1 - 2e-72 244.1 22.2 2.1e-47 161.5 9.1 3.0 1 1 2 3 3 3 3 BT1 family MFS_1 PF07690.16 EKX41442.1 - 5.2e-21 75.0 26.5 5.2e-21 75.0 26.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EKX41442.1 - 2e-07 30.3 11.6 2.9e-07 29.7 11.6 1.3 1 0 0 1 1 1 1 MFS_1 like family PUCC PF03209.15 EKX41442.1 - 2.1e-06 27.0 1.1 5.3e-05 22.4 1.1 2.3 1 1 0 1 1 1 1 PUCC protein Kinesin PF00225.23 EKX41443.1 - 6.8e-91 304.7 1.4 8.3e-91 304.4 1.4 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX41443.1 - 6.2e-16 58.7 0.1 5.6e-15 55.6 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding Dus PF01207.17 EKX41444.1 - 9.9e-71 238.4 0.0 1.1e-70 238.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) SOR_SNZ PF01680.17 EKX41444.1 - 0.003 17.4 0.5 0.011 15.5 0.2 1.8 1 1 1 2 2 2 1 SOR/SNZ family DHO_dh PF01180.21 EKX41444.1 - 0.0035 16.6 0.0 0.28 10.4 0.0 2.1 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 EKX41444.1 - 0.0056 16.2 0.0 0.0093 15.4 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein TMP-TENI PF02581.17 EKX41444.1 - 0.021 14.2 0.1 0.036 13.4 0.1 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase ThiG PF05690.14 EKX41444.1 - 0.022 14.1 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG G3P_antiterm PF04309.12 EKX41444.1 - 0.025 14.0 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator DUF5324 PF17258.2 EKX41444.1 - 0.053 13.2 1.3 0.091 12.4 0.5 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5324) MR_MLE_C PF13378.6 EKX41444.1 - 0.11 12.0 0.1 0.32 10.5 0.0 1.8 2 0 0 2 2 2 0 Enolase C-terminal domain-like Thiolase_N PF00108.23 EKX41445.1 - 3e-79 266.0 0.0 3.9e-78 262.4 0.0 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EKX41445.1 - 1e-40 138.2 0.0 1.9e-40 137.3 0.0 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EKX41445.1 - 6.4e-07 29.2 0.7 3.1e-06 27.0 0.0 2.4 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 EKX41445.1 - 0.015 14.0 0.0 0.036 12.8 0.0 1.6 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) Ketoacyl-synt_C PF02801.22 EKX41445.1 - 0.058 13.4 0.0 28 4.8 0.0 3.2 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain ArfGap PF01412.18 EKX41446.1 - 0.043 13.9 0.1 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Ad_cyc_g-alpha PF08509.11 EKX41446.1 - 0.09 12.5 0.5 0.18 11.6 0.5 1.5 1 0 0 1 1 1 0 Adenylate cyclase G-alpha binding domain PPR_2 PF13041.6 EKX41447.1 - 1.7e-80 265.1 17.9 5.5e-09 36.1 0.0 16.4 14 3 3 17 17 16 14 PPR repeat family PPR_3 PF13812.6 EKX41447.1 - 2.5e-76 251.7 0.7 1.7e-09 37.6 0.0 15.0 13 2 3 16 16 16 13 Pentatricopeptide repeat domain PPR_1 PF12854.7 EKX41447.1 - 7.6e-42 140.7 3.9 0.0028 17.3 0.0 15.7 14 1 0 14 14 14 9 PPR repeat PPR_long PF17177.4 EKX41447.1 - 2e-36 125.4 8.5 1.4e-07 31.1 0.2 8.0 3 2 3 8 8 8 7 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EKX41447.1 - 1.5e-10 40.6 53.0 0.028 14.7 0.0 18.5 20 0 0 20 20 19 3 PPR repeat EF-hand_1 PF00036.32 EKX41447.1 - 4.3e-10 38.4 2.4 1.7e-05 24.0 0.2 3.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX41447.1 - 4.8e-10 38.5 0.8 0.00011 21.9 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EKX41447.1 - 1e-09 38.7 0.1 4e-09 36.8 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX41447.1 - 1.1e-09 37.4 2.5 7e-05 22.1 0.5 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX41447.1 - 1.6e-05 24.6 0.2 0.028 14.2 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain pair DUF4392 PF14336.6 EKX41447.1 - 0.0054 16.2 0.1 0.011 15.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) Exog_C PF18026.1 EKX41447.1 - 0.019 15.0 4.2 0.25 11.4 0.0 4.6 7 0 0 7 7 7 0 Endo/exonuclease (EXOG) C-terminal domain GMP_synt_C PF00958.22 EKX41447.1 - 0.12 12.4 0.2 8.3 6.5 0.0 3.8 4 1 1 5 5 5 0 GMP synthase C terminal domain EF-hand_4 PF12763.7 EKX41447.1 - 0.16 12.0 0.1 0.55 10.2 0.0 1.9 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Kdo PF06293.14 EKX41448.1 - 1.5e-11 44.1 0.2 3.4e-11 42.9 0.2 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EKX41448.1 - 6.9e-11 42.0 0.0 8.3e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EKX41448.1 - 1.4e-09 37.8 0.0 2.4e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 EKX41448.1 - 3.2e-09 36.5 0.0 1e-08 34.8 0.0 1.7 1 1 1 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EKX41448.1 - 1.4e-08 35.0 0.0 0.0036 17.3 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 EKX41448.1 - 0.00046 19.8 0.1 0.0012 18.5 0.1 1.7 1 1 1 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 EKX41448.1 - 0.006 15.9 0.1 0.0073 15.6 0.1 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase YrbL-PhoP_reg PF10707.9 EKX41448.1 - 0.056 12.9 0.1 0.28 10.7 0.0 2.1 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL APH_6_hur PF04655.14 EKX41448.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase CHCH PF06747.13 EKX41449.1 - 9.2e-07 28.8 5.3 1.4e-06 28.3 5.3 1.3 1 0 0 1 1 1 1 CHCH domain NDUF_B7 PF05676.13 EKX41449.1 - 0.0007 19.3 1.5 0.00081 19.1 1.5 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 EKX41449.1 - 0.00079 19.4 5.2 0.26 11.4 1.2 2.0 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 EKX41449.1 - 0.0078 16.5 4.5 0.025 14.9 4.4 1.7 1 1 1 2 2 2 1 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.17 EKX41449.1 - 0.024 14.9 0.6 0.029 14.6 0.6 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb CX9C PF16860.5 EKX41449.1 - 0.043 13.8 5.5 0.62 10.1 5.1 2.1 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 EKX41449.1 - 0.11 12.9 6.4 0.31 11.4 1.2 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) DUF2808 PF10989.8 EKX41450.1 - 4.4e-07 30.0 3.6 0.019 15.0 0.0 6.4 7 0 0 7 7 7 2 Protein of unknown function (DUF2808) WW PF00397.26 EKX41450.1 - 0.02 14.9 0.0 0.057 13.5 0.0 1.8 1 0 0 1 1 1 0 WW domain DUF645 PF04875.12 EKX41454.1 - 1.6 8.8 3.8 56 3.9 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function, DUF645 CBFD_NFYB_HMF PF00808.23 EKX41456.1 - 2.9e-18 65.9 0.0 3.2e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EKX41456.1 - 2.7e-06 27.8 0.0 3.2e-06 27.5 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 EKX41456.1 - 0.026 14.6 0.0 0.029 14.5 0.0 1.1 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Ephrin_rec_like PF07699.13 EKX41457.1 - 8.3e-28 95.9 58.2 2.2e-09 36.9 3.1 5.5 2 2 4 6 6 6 6 Putative ephrin-receptor like NCD3G PF07562.14 EKX41457.1 - 8.1e-09 35.3 28.5 0.0033 17.4 0.8 4.9 1 1 2 5 5 5 4 Nine Cysteines Domain of family 3 GPCR Furin-like_2 PF15913.5 EKX41457.1 - 1.6e-05 25.0 2.6 1.6e-05 25.0 2.6 2.5 1 1 2 3 3 3 2 Furin-like repeat, cysteine-rich TNFR_c6 PF00020.18 EKX41457.1 - 1.9e-05 25.0 34.6 0.088 13.2 0.9 6.4 2 1 2 5 5 5 4 TNFR/NGFR cysteine-rich region VSP PF03302.13 EKX41457.1 - 0.21 10.4 28.1 0.017 14.0 9.2 2.2 1 1 1 2 2 2 0 Giardia variant-specific surface protein DUF2318 PF10080.9 EKX41457.1 - 6.3 7.0 18.8 1.3 9.1 2.0 3.2 2 1 1 3 3 3 0 Predicted membrane protein (DUF2318) EF1G PF00647.19 EKX41458.1 - 0.0026 17.8 0.5 0.0068 16.5 0.5 1.7 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain Glyco_transf_88 PF16849.5 EKX41458.1 - 0.024 13.6 1.2 0.028 13.3 1.2 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 88 SPATA1_C PF15743.5 EKX41458.1 - 1.1 9.3 15.4 1.8 8.7 11.2 2.2 1 1 1 2 2 2 0 Spermatogenesis-associated C-terminus TIR_2 PF13676.6 EKX41459.1 - 7.8e-09 36.2 0.2 3.8e-08 33.9 0.0 2.3 4 0 0 4 4 4 1 TIR domain Arm PF00514.23 EKX41459.1 - 0.00032 20.6 0.5 0.36 10.9 0.1 4.0 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat DUF493 PF04359.14 EKX41460.1 - 1.6e-18 67.1 0.0 2.3e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF493) ACT_4 PF13291.6 EKX41460.1 - 0.003 18.1 0.0 0.0051 17.4 0.0 1.3 1 0 0 1 1 1 1 ACT domain Laminin_G_3 PF13385.6 EKX41461.1 - 2e-06 28.0 0.9 1.9e-05 24.9 0.2 2.8 2 1 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Filamin PF00630.19 EKX41461.1 - 5.8e-05 23.8 0.0 14 6.6 0.0 3.9 3 0 0 3 3 3 3 Filamin/ABP280 repeat EGF PF00008.27 EKX41461.1 - 0.0016 18.7 8.1 0.0016 18.7 8.1 2.4 2 0 0 2 2 2 1 EGF-like domain DUF1080 PF06439.11 EKX41461.1 - 0.0033 17.5 0.0 0.011 15.9 0.0 1.8 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1080) EGF_2 PF07974.13 EKX41461.1 - 0.0094 16.3 10.6 0.029 14.7 10.6 2.0 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 EKX41461.1 - 2.6 8.2 9.2 11 6.2 9.2 2.2 1 0 0 1 1 1 0 Tenascin EGF domain EGF_CA PF07645.15 EKX41461.1 - 3.2 8.0 6.0 13 6.1 6.0 2.1 1 0 0 1 1 1 0 Calcium-binding EGF domain ABC_membrane PF00664.23 EKX41463.1 - 1.6e-39 136.3 5.0 2.1e-39 135.8 5.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EKX41463.1 - 3.3e-28 98.9 0.0 6.4e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EKX41463.1 - 4.8e-05 22.9 0.0 0.00017 21.1 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EKX41463.1 - 0.0066 16.4 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase CbiA PF01656.23 EKX41463.1 - 0.012 15.7 0.4 7.7 6.6 0.0 3.1 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_15 PF13175.6 EKX41463.1 - 0.027 14.2 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 EKX41463.1 - 0.027 14.7 0.1 0.87 9.9 0.1 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit APS_kinase PF01583.20 EKX41463.1 - 0.05 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_25 PF13481.6 EKX41463.1 - 0.052 13.1 0.0 0.26 10.8 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 EKX41463.1 - 0.059 13.8 0.1 1.1 9.7 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EKX41463.1 - 0.06 13.1 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.7 EKX41463.1 - 0.071 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.6 EKX41463.1 - 0.077 13.3 0.2 0.35 11.2 0.1 2.2 2 1 0 2 2 1 0 AAA domain AAA_24 PF13479.6 EKX41463.1 - 0.079 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EKX41463.1 - 0.12 11.7 0.0 0.3 10.3 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 EKX41463.1 - 0.15 12.6 0.0 0.69 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EKX41463.1 - 0.15 12.1 0.1 0.35 10.9 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain DUF5313 PF17240.2 EKX41463.1 - 0.8 10.1 2.8 0.82 10.1 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5313) Cofilin_ADF PF00241.20 EKX41464.1 - 5.2e-18 65.0 0.0 9.2e-11 41.6 0.0 3.0 2 1 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF4581 PF15167.6 EKX41464.1 - 0.0068 16.6 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4581) Baculo_PEP_C PF04513.12 EKX41464.1 - 5 7.2 6.7 7.5 6.6 0.8 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ephrin_rec_like PF07699.13 EKX41465.1 - 6.5e-06 25.8 58.6 0.01 15.6 3.5 8.4 4 3 3 7 7 7 7 Putative ephrin-receptor like NCD3G PF07562.14 EKX41465.1 - 0.0056 16.6 45.1 0.48 10.4 6.5 7.1 4 3 1 5 5 5 5 Nine Cysteines Domain of family 3 GPCR SHIPPO-rpt PF07004.12 EKX41466.1 - 4.8e-11 43.0 16.6 0.0014 19.4 0.7 3.4 3 0 0 3 3 3 3 Sperm-tail PG-rich repeat RRM_1 PF00076.22 EKX41468.1 - 6.4e-30 102.8 0.0 1.5e-11 43.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 EKX41468.1 - 0.0024 17.7 0.0 0.0084 16.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4523) Nup35_RRM_2 PF14605.6 EKX41468.1 - 0.0052 16.8 0.1 0.012 15.6 0.1 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EKX41468.1 - 0.0097 15.7 0.0 0.14 12.0 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif Exo_endo_phos PF03372.23 EKX41469.1 - 9e-08 31.9 0.0 1.7e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MFS_1 PF07690.16 EKX41470.1 - 2.5e-31 108.9 28.6 6.2e-17 61.5 5.8 2.5 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EKX41470.1 - 0.0008 18.4 9.7 0.0017 17.3 1.4 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter PEPCK_ATP PF01293.20 EKX41471.1 - 4.5e-12 45.4 0.1 6.1e-06 25.2 0.0 2.6 2 1 1 3 3 3 2 Phosphoenolpyruvate carboxykinase PA PF02225.22 EKX41472.1 - 2.2e-14 53.2 0.1 3.7e-14 52.5 0.1 1.4 1 0 0 1 1 1 1 PA domain RNase_E_G PF10150.9 EKX41474.1 - 0.0066 15.9 1.4 0.0098 15.3 1.1 1.3 1 1 0 1 1 1 1 Ribonuclease E/G family FTA4 PF13093.6 EKX41474.1 - 0.022 14.7 4.8 0.049 13.5 4.8 1.6 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 TAFII28 PF04719.14 EKX41474.1 - 0.13 12.4 3.1 10 6.3 0.8 2.5 2 0 0 2 2 2 0 hTAFII28-like protein conserved region WW PF00397.26 EKX41475.1 - 7.3e-11 42.0 1.6 1.1e-10 41.4 1.6 1.3 1 0 0 1 1 1 1 WW domain Rsm22 PF09243.10 EKX41476.1 - 2.6e-26 92.5 0.2 1.5e-15 57.3 0.1 2.9 1 1 1 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 Pro_isomerase PF00160.21 EKX41477.1 - 1.3e-46 158.7 0.0 1.5e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Transglut_core2 PF13369.6 EKX41478.1 - 3.9e-33 114.2 0.0 6.7e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily BORCS6 PF10157.9 EKX41478.1 - 0.096 12.9 0.7 11 6.2 0.2 2.3 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 6 Transglut_core PF01841.19 EKX41478.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily Pro_isomerase PF00160.21 EKX41479.1 - 1.2e-13 51.6 0.0 2e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_C13 PF01650.18 EKX41480.1 - 9.6e-34 117.0 0.0 1.3e-33 116.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family Cpta_toxin PF07254.12 EKX41480.1 - 0.16 12.0 0.1 0.45 10.5 0.0 1.7 2 0 0 2 2 2 0 Membrane-bound toxin component of toxin-antitoxin system CRAL_TRIO PF00650.20 EKX41481.1 - 3.8e-18 65.7 0.0 3.9e-18 65.7 0.0 1.0 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EKX41481.1 - 0.0013 18.9 0.1 0.0014 18.8 0.1 1.0 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain TatC PF00902.18 EKX41481.1 - 0.059 13.2 0.0 0.063 13.1 0.0 1.1 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) Voltage_CLC PF00654.20 EKX41482.1 - 1.6e-83 280.9 23.1 2.7e-83 280.2 23.1 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 EKX41482.1 - 1.4e-07 31.9 0.4 0.0023 18.3 0.2 2.5 2 0 0 2 2 2 2 CBS domain zf-met PF12874.7 EKX41483.1 - 8.1e-08 32.4 0.4 2.1e-07 31.1 0.4 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EKX41483.1 - 2.8e-07 30.6 0.9 5.2e-07 29.8 0.1 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EKX41483.1 - 0.02 15.2 3.6 0.021 15.2 2.2 1.7 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 EKX41483.1 - 0.036 14.5 0.3 0.073 13.6 0.3 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EKX41483.1 - 0.048 14.5 0.1 0.12 13.2 0.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger dsrm PF00035.26 EKX41485.1 - 9.6e-06 26.2 0.1 2e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 EKX41485.1 - 0.00013 22.5 0.1 0.0026 18.4 0.0 2.3 1 1 1 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EKX41485.1 - 0.0002 21.5 0.0 0.00096 19.3 0.0 2.1 2 1 0 2 2 2 1 Ribonuclease-III-like EPTP PF03736.17 EKX41486.1 - 7.9e-18 64.2 2.7 0.0014 18.6 0.1 6.5 6 0 0 6 6 6 4 EPTP domain Lectin_C PF00059.21 EKX41486.1 - 2.1e-13 51.0 1.2 2.1e-13 51.0 1.2 3.0 3 0 0 3 3 3 1 Lectin C-type domain SAM_adeno_trans PF01887.16 EKX41486.1 - 0.0075 15.7 0.0 0.65 9.4 0.0 4.4 4 0 0 4 4 4 1 S-adenosyl-l-methionine hydroxide adenosyltransferase EGF_2 PF07974.13 EKX41486.1 - 0.037 14.4 30.4 0.025 14.9 4.3 5.5 4 0 0 4 4 4 0 EGF-like domain Kelch_6 PF13964.6 EKX41486.1 - 0.11 12.8 1.1 2.3 8.6 0.0 3.4 3 0 0 3 3 3 0 Kelch motif DUF4381 PF14316.6 EKX41486.1 - 0.16 12.2 1.1 0.3 11.3 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Filamin PF00630.19 EKX41487.1 - 6.5e-41 139.3 0.0 4.2e-18 66.1 0.0 3.1 3 0 0 3 3 3 3 Filamin/ABP280 repeat Invasin_D3 PF09134.10 EKX41487.1 - 3.3e-06 27.3 11.8 0.0075 16.5 0.3 3.3 3 0 0 3 3 3 2 Invasin, domain 3 DUF5011 PF16403.5 EKX41487.1 - 0.00086 19.4 2.5 0.2 11.8 0.3 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF5011) DUF5060 PF16586.5 EKX41487.1 - 0.0023 18.3 0.0 8.3 6.9 0.0 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF5060) DUF1541 PF07563.11 EKX41487.1 - 0.092 12.6 0.8 6.5 6.7 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1541) DUF1831 PF08866.10 EKX41487.1 - 0.1 13.1 0.0 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 Putative amino acid metabolism Y_Y_Y PF07495.13 EKX41487.1 - 0.15 12.1 0.9 6.4 6.8 0.1 2.6 2 0 0 2 2 2 0 Y_Y_Y domain DEAD PF00270.29 EKX41488.1 - 1.3e-18 67.4 0.0 4.3e-15 55.9 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX41488.1 - 3.1e-17 62.9 0.0 1.9e-16 60.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EKX41488.1 - 8.3e-07 29.6 0.1 3.8e-06 27.5 0.1 2.1 2 0 0 2 2 2 1 RecQ zinc-binding T4SS-DNA_transf PF02534.14 EKX41488.1 - 0.081 11.7 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer TPR_12 PF13424.6 EKX41489.1 - 0.0039 17.4 0.2 0.0039 17.4 0.2 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat CRAL_TRIO PF00650.20 EKX41490.1 - 8.8e-22 77.5 0.0 1.2e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EKX41490.1 - 0.004 17.3 0.0 0.0074 16.4 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain LSM14 PF12701.7 EKX41490.1 - 0.18 12.0 0.0 0.47 10.6 0.0 1.7 1 0 0 1 1 1 0 Scd6-like Sm domain Tape_meas_lam_C PF09718.10 EKX41491.1 - 0.067 13.3 0.1 2 8.6 0.0 2.3 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Hexapep PF00132.24 EKX41492.1 - 1.2e-15 56.5 8.3 0.00019 21.0 1.1 4.3 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EKX41492.1 - 5.6e-09 35.6 7.0 0.0096 15.7 0.9 4.3 4 0 0 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EKX41492.1 - 0.0079 15.2 0.0 0.11 11.5 0.0 2.1 1 1 1 2 2 2 1 L-fucokinase Sod_Ni PF09055.11 EKX41493.1 - 4.4e-08 33.7 0.0 4.9e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Nickel-containing superoxide dismutase DEAD PF00270.29 EKX41494.1 - 2.8e-40 138.0 0.2 4.5e-40 137.3 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX41494.1 - 5e-28 97.7 0.7 8.6e-25 87.2 0.2 2.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 EKX41494.1 - 4.8e-08 33.2 0.0 9e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 EKX41494.1 - 0.00058 19.5 0.1 0.001 18.7 0.1 1.5 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 EKX41494.1 - 0.017 15.4 0.5 0.057 13.7 0.5 2.0 1 1 0 1 1 1 0 AAA domain Tho2 PF11262.8 EKX41495.1 - 0.0072 15.6 1.9 0.0072 15.6 1.9 2.5 2 0 0 2 2 2 2 Transcription factor/nuclear export subunit protein 2 zf-CCHC_6 PF15288.6 EKX41495.1 - 0.031 14.1 0.2 0.069 13.0 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle Fer4_18 PF13746.6 EKX41495.1 - 0.14 12.4 0.0 0.14 12.4 0.0 3.1 3 1 0 3 3 3 0 4Fe-4S dicluster domain Methyltr_RsmB-F PF01189.17 EKX41496.1 - 7e-26 91.1 0.0 1.3e-25 90.2 0.0 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 EKX41496.1 - 7.4e-05 23.4 0.0 0.00021 21.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX41496.1 - 0.00013 21.4 0.1 0.00021 20.7 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 EKX41496.1 - 0.00018 21.7 0.1 0.00038 20.6 0.1 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 EKX41496.1 - 0.0002 21.2 0.0 0.00042 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Metal_CEHH PF14455.6 EKX41496.1 - 0.001 18.7 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Predicted metal binding domain Ank_4 PF13637.6 EKX41497.1 - 3.3e-12 46.7 0.2 2.8e-07 30.9 0.0 3.4 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX41497.1 - 5.6e-12 45.5 0.0 7.4e-08 32.5 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EKX41497.1 - 4.2e-11 42.1 0.0 1.3e-06 28.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EKX41497.1 - 5.9e-11 42.8 0.0 1.1e-10 42.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX41497.1 - 1.1e-10 41.5 0.0 3.2e-10 40.0 0.1 1.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX41498.1 - 8.4e-12 45.0 2.8 2.5e-06 27.7 0.1 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EKX41498.1 - 4.3e-11 43.3 0.2 5.3e-11 42.9 0.2 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX41498.1 - 9.3e-10 38.6 0.3 9.3e-09 35.4 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX41498.1 - 1.4e-09 37.4 1.4 7.1e-05 22.9 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EKX41498.1 - 3.9e-09 36.9 0.6 1.7e-06 28.5 0.2 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) DUF3396 PF11876.8 EKX41498.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3396) Pkinase PF00069.25 EKX41499.1 - 2.3e-46 158.3 0.2 3.5e-46 157.7 0.2 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX41499.1 - 8.3e-22 77.7 0.2 1.3e-21 77.1 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX41499.1 - 0.0053 15.6 1.7 0.053 12.3 0.0 2.0 1 1 1 2 2 2 1 Fungal protein kinase DUF5617 PF18493.1 EKX41499.1 - 0.2 11.8 0.1 0.2 11.8 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5617) DBP10CT PF08147.12 EKX41499.1 - 2.7 8.3 4.6 5.6 7.3 0.3 2.5 1 1 1 2 2 2 0 DBP10CT (NUC160) domain Csm1_N PF18504.1 EKX41500.1 - 0.093 13.1 2.6 0.64 10.4 2.6 2.3 1 1 0 1 1 1 0 Csm1 N-terminal domain DUF641 PF04859.12 EKX41500.1 - 0.11 12.8 1.6 0.24 11.8 1.6 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) PolyA_pol_arg_C PF12626.7 EKX41500.1 - 0.21 11.7 3.3 3.3 7.8 3.3 2.4 1 1 0 1 1 1 0 Polymerase A arginine-rich C-terminus ALMT PF11744.8 EKX41500.1 - 5 5.8 5.1 7 5.4 5.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4596 PF15363.6 EKX41501.1 - 0.13 12.6 1.5 0.24 11.6 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4596) ResIII PF04851.15 EKX41502.1 - 2.2e-05 24.5 2.2 0.0016 18.5 0.0 3.3 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EKX41502.1 - 0.00057 19.4 0.0 0.0018 17.8 0.0 1.8 1 0 0 1 1 1 1 PhoH-like protein UvrD_C_2 PF13538.6 EKX41502.1 - 0.0016 18.2 0.0 0.0056 16.5 0.0 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_25 PF13481.6 EKX41502.1 - 0.005 16.4 0.2 0.037 13.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EKX41502.1 - 0.007 16.1 0.1 0.055 13.2 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_30 PF13604.6 EKX41502.1 - 0.017 14.8 0.0 0.081 12.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EKX41502.1 - 0.023 15.1 0.1 0.19 12.1 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 EKX41502.1 - 0.024 14.1 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 EKX41502.1 - 0.025 13.9 0.0 0.09 12.1 0.0 1.9 2 0 0 2 2 2 0 KaiC DUF5631 PF18645.1 EKX41502.1 - 0.052 13.9 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5631) AAA_12 PF13087.6 EKX41502.1 - 0.054 13.1 0.1 0.25 11.0 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 EKX41502.1 - 0.096 12.4 0.1 2.2 8.0 0.0 3.0 2 1 0 2 2 2 0 AAA domain HEAT PF02985.22 EKX41504.1 - 6.2e-11 41.6 7.3 0.00028 20.9 0.0 4.7 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.6 EKX41504.1 - 4.1e-07 30.4 0.6 0.018 15.6 0.0 4.7 4 0 0 4 4 4 1 HEAT-like repeat HEAT_2 PF13646.6 EKX41504.1 - 4.7e-06 26.9 0.0 0.023 15.1 0.0 2.9 3 0 0 3 3 3 2 HEAT repeats Vac14_Fab1_bd PF12755.7 EKX41504.1 - 3.1e-05 24.5 0.0 3 8.5 0.0 3.5 2 1 1 3 3 3 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EKX41504.1 - 0.0003 20.9 0.0 1.3 9.1 0.0 2.9 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 NopRA1 PF16201.5 EKX41504.1 - 0.014 15.0 0.1 1 8.9 0.0 3.1 2 1 1 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 MMS19_N PF14500.6 EKX41504.1 - 0.056 13.0 0.0 4.9 6.7 0.0 2.5 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II DRIM PF07539.12 EKX41504.1 - 0.069 11.4 0.0 0.11 10.8 0.0 1.4 1 0 0 1 1 1 0 Down-regulated in metastasis MTA_R1 PF17226.2 EKX41504.1 - 0.1 12.7 0.0 4 7.7 0.0 2.6 2 0 0 2 2 2 0 MTA R1 domain FliT PF05400.13 EKX41504.1 - 2.9 8.8 4.6 20 6.1 0.0 3.4 4 0 0 4 4 4 0 Flagellar protein FliT SDA1 PF05285.12 EKX41505.1 - 8.7e-32 110.9 56.2 3.9e-27 95.6 0.2 3.7 3 1 0 3 3 3 2 SDA1 NUC130_3NT PF08158.12 EKX41505.1 - 1.4e-07 31.7 0.6 9e-07 29.1 0.1 2.6 2 0 0 2 2 2 1 NUC130/3NT domain EF-hand_7 PF13499.6 EKX41506.1 - 2.1e-11 44.1 0.1 3.6e-11 43.3 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX41506.1 - 5.7e-09 34.9 1.3 3.2e-06 26.3 0.2 2.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EKX41506.1 - 4.9e-08 32.3 0.1 1.2e-05 24.9 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain LRR_6 PF13516.6 EKX41506.1 - 2.6e-07 30.2 1.7 0.4 10.9 0.0 4.1 4 0 0 4 4 4 3 Leucine Rich repeat EF-hand_5 PF13202.6 EKX41506.1 - 5.5e-06 25.6 0.6 0.0061 16.0 0.1 2.7 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EKX41506.1 - 2.1e-05 24.2 1.1 0.0086 15.9 0.3 2.5 2 0 0 2 2 2 2 EF-hand domain pair LRR_4 PF12799.7 EKX41506.1 - 0.0092 16.4 0.0 0.78 10.3 0.0 2.3 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX41506.1 - 0.19 12.4 0.0 1.4e+02 3.7 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich Repeat EF-hand_4 PF12763.7 EKX41506.1 - 0.3 11.0 1.6 3.2 7.7 0.1 2.6 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF4834 PF16118.5 EKX41506.1 - 3.2 8.8 5.3 0.93 10.5 1.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) NTF2 PF02136.20 EKX41507.1 - 2.4e-31 108.8 0.1 2.7e-31 108.6 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 EKX41507.1 - 0.018 15.5 0.0 0.022 15.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Vac_ImportDeg PF09783.9 EKX41507.1 - 0.065 13.0 0.4 0.53 10.1 0.2 2.0 1 1 1 2 2 2 0 Vacuolar import and degradation protein DUF4033 PF13225.6 EKX41509.1 - 1.8e-27 95.1 0.2 3.6e-27 94.2 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4033) adh_short PF00106.25 EKX41510.1 - 4.6e-29 101.3 0.1 5.7e-28 97.7 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EKX41510.1 - 4.4e-21 75.5 0.0 4.1e-20 72.4 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX41510.1 - 5.6e-09 36.2 0.1 8.5e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EKX41510.1 - 0.0028 17.2 0.0 0.0044 16.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EKX41510.1 - 0.044 13.2 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Methyltransf_11 PF08241.12 EKX41511.1 - 2.9e-16 59.9 0.0 4.3e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX41511.1 - 3.2e-16 59.8 0.0 4.4e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX41511.1 - 1.4e-08 34.8 0.0 2e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EKX41511.1 - 1.8e-08 34.0 0.1 2.2e-08 33.7 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 EKX41511.1 - 5.4e-08 32.8 0.0 6.8e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX41511.1 - 1.1e-07 32.6 0.0 1.5e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX41511.1 - 1.7e-07 30.9 0.0 2.1e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ADH_zinc_N PF00107.26 EKX41511.1 - 0.0004 20.4 0.0 0.00057 19.9 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FtsJ PF01728.19 EKX41511.1 - 0.0073 16.4 0.0 0.026 14.6 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 EKX41511.1 - 0.013 15.2 0.2 0.024 14.4 0.3 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0146 PF03686.13 EKX41511.1 - 0.037 13.9 0.1 0.052 13.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) DUF2759 PF10958.8 EKX41511.1 - 0.048 13.4 0.1 0.048 13.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) Met_10 PF02475.16 EKX41511.1 - 0.049 13.4 0.0 0.065 13.0 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_16 PF10294.9 EKX41511.1 - 0.054 13.2 0.0 0.061 13.0 0.0 1.1 1 0 0 1 1 1 0 Lysine methyltransferase Methyltr_RsmB-F PF01189.17 EKX41511.1 - 0.084 12.5 0.0 0.16 11.6 0.0 1.4 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F CheR PF01739.18 EKX41511.1 - 0.11 12.0 0.1 13 5.2 0.0 2.1 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_8 PF05148.15 EKX41511.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase PMM PF03332.13 EKX41512.1 - 4.1e-106 353.7 0.7 4.8e-106 353.5 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EKX41512.1 - 2.9e-06 27.2 0.0 7.9e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EKX41512.1 - 3.9e-05 23.3 0.0 0.021 14.4 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase ATP-synt_C PF00137.21 EKX41513.1 - 6.8e-33 112.8 39.5 6.1e-21 74.5 14.8 2.2 2 0 0 2 2 2 2 ATP synthase subunit C Thioredoxin PF00085.20 EKX41514.1 - 1.2e-16 60.5 0.2 3.6e-13 49.4 0.1 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_7 PF13899.6 EKX41514.1 - 5.6e-06 26.5 0.0 1.1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EKX41514.1 - 0.008 16.6 0.4 0.33 11.4 0.2 2.4 2 1 0 2 2 2 1 Thioredoxin-like domain ASH PF15780.5 EKX41515.1 - 5.3e-07 29.8 0.0 0.0035 17.5 0.0 2.6 2 0 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 EKX41515.1 - 2.5e-05 24.4 0.0 5.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Flagellar-associated PapD-like TMEM131_like PF12371.8 EKX41515.1 - 0.17 12.2 0.8 1.3 9.4 0.1 2.5 2 0 0 2 2 2 0 Transmembrane protein 131-like XhlA PF10779.9 EKX41516.1 - 0.16 12.2 0.7 0.27 11.5 0.7 1.3 1 0 0 1 1 1 0 Haemolysin XhlA Sugarporin_N PF11471.8 EKX41516.1 - 0.22 11.5 2.6 0.42 10.6 2.6 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension BMFP PF04380.13 EKX41516.1 - 0.24 11.9 2.9 0.4 11.2 2.9 1.3 1 0 0 1 1 1 0 Membrane fusogenic activity DUF5320 PF17253.2 EKX41516.1 - 0.85 10.7 9.4 78 4.4 9.4 2.3 1 1 0 1 1 1 0 Family of unknown function (DUF5320) Asp PF00026.23 EKX41517.1 - 7e-28 98.0 0.0 4.4e-18 65.8 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EKX41517.1 - 4.1e-07 30.4 0.0 0.00027 21.2 0.0 2.7 2 0 0 2 2 2 2 Xylanase inhibitor N-terminal DAP10 PF07213.11 EKX41517.1 - 0.051 13.5 0.5 0.15 12.1 0.5 1.8 1 0 0 1 1 1 0 DAP10 membrane protein DUF4229 PF14012.6 EKX41517.1 - 1.7 8.8 6.9 1.6 8.9 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) GCV_H PF01597.19 EKX41518.1 - 0.00015 21.7 0.0 0.0003 20.7 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein UFD1 PF03152.14 EKX41518.1 - 0.073 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 DUF4520 PF15016.6 EKX41518.1 - 0.15 12.2 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) FAM176 PF14851.6 EKX41519.1 - 0.013 15.2 4.9 0.013 15.2 4.9 3.1 1 1 0 2 2 2 0 FAM176 family FGF-BP1 PF06473.12 EKX41519.1 - 0.71 9.7 7.6 0.081 12.7 3.4 1.5 1 1 1 2 2 2 0 FGF binding protein 1 (FGF-BP1) Trypan_PARP PF05887.11 EKX41519.1 - 2.4 8.1 38.7 3.3 7.7 28.7 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Presenilin PF01080.17 EKX41519.1 - 4.6 5.9 8.6 6 5.5 8.6 1.2 1 0 0 1 1 1 0 Presenilin RAB3GAP2_C PF14656.6 EKX41519.1 - 5.3 5.2 7.1 0.16 10.1 1.1 1.5 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit C-terminus DUF4265 PF14085.6 EKX41520.1 - 0.031 14.2 0.4 46 4.0 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4265) Presenilin PF01080.17 EKX41521.1 - 1.5 7.5 3.6 2 7.1 3.6 1.2 1 0 0 1 1 1 0 Presenilin Abhydrolase_1 PF00561.20 EKX41522.1 - 2.7e-11 43.6 0.0 1.2e-10 41.5 0.0 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EKX41522.1 - 2e-05 24.0 0.0 4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EKX41522.1 - 0.0072 16.9 0.1 0.012 16.2 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family IFT57 PF10498.9 EKX41523.1 - 0.00031 19.8 1.3 0.0006 18.9 1.3 1.5 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Fib_alpha PF08702.10 EKX41523.1 - 0.00055 20.1 2.2 0.001 19.2 2.2 1.4 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family CLZ PF16526.5 EKX41523.1 - 0.0041 17.4 1.4 0.0041 17.4 1.4 2.4 2 0 0 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Taxilin PF09728.9 EKX41523.1 - 0.011 14.9 6.8 0.017 14.3 6.8 1.3 1 0 0 1 1 1 0 Myosin-like coiled-coil protein DUF72 PF01904.18 EKX41523.1 - 0.078 13.1 0.2 0.11 12.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF72 Laminin_II PF06009.12 EKX41523.1 - 0.078 13.0 4.5 0.29 11.2 4.1 1.8 1 1 0 1 1 1 0 Laminin Domain II Prefoldin_2 PF01920.20 EKX41523.1 - 0.11 12.4 6.7 1.4 8.9 1.1 2.5 1 1 1 2 2 2 0 Prefoldin subunit TMPIT PF07851.13 EKX41523.1 - 0.27 10.5 2.9 0.37 10.0 2.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 EKX41523.1 - 0.36 10.2 8.5 2.1 7.6 8.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SlyX PF04102.12 EKX41523.1 - 0.63 10.7 7.2 0.89 10.2 3.2 2.8 2 0 0 2 2 2 0 SlyX CCDC-167 PF15188.6 EKX41523.1 - 0.8 10.1 11.7 1.9 8.9 0.7 3.1 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 TPR_MLP1_2 PF07926.12 EKX41523.1 - 0.83 9.7 13.4 0.068 13.2 7.9 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.21 EKX41525.1 - 0.00066 19.7 2.7 0.00066 19.7 2.7 6.0 4 2 1 5 5 5 1 bZIP transcription factor DivIC PF04977.15 EKX41525.1 - 0.007 16.1 3.5 0.007 16.1 3.5 6.8 4 3 4 8 8 8 2 Septum formation initiator TMPIT PF07851.13 EKX41525.1 - 0.011 15.0 10.4 0.011 15.0 10.4 3.5 2 2 2 4 4 4 0 TMPIT-like protein ZapB PF06005.12 EKX41525.1 - 0.037 14.5 3.5 0.037 14.5 3.5 6.9 3 1 1 4 4 4 0 Cell division protein ZapB Filament PF00038.21 EKX41525.1 - 0.6 9.6 61.5 0.46 10.0 26.0 3.6 1 1 1 3 3 3 0 Intermediate filament protein HIP1_clath_bdg PF16515.5 EKX41525.1 - 0.64 10.7 67.7 0.37 11.4 11.8 5.6 1 1 5 6 6 6 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Golgin_A5 PF09787.9 EKX41525.1 - 7.2 6.0 69.0 2.2 7.7 31.6 3.5 1 1 2 3 3 3 0 Golgin subfamily A member 5 Fez1 PF06818.15 EKX41525.1 - 8.3 6.8 61.9 0.24 11.8 25.9 3.9 1 1 2 3 3 3 0 Fez1 CRAL_TRIO PF00650.20 EKX41526.1 - 3.6e-12 46.3 0.0 6.9e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 EKX41526.1 - 6.4e-06 26.7 9.4 6.4e-06 26.7 9.4 3.2 2 1 0 2 2 2 1 Golgi-dynamics membrane-trafficking Sigma70_ner PF04546.13 EKX41526.1 - 0.0034 17.3 15.4 0.1 12.4 10.5 2.3 2 0 0 2 2 2 2 Sigma-70, non-essential region SDA1 PF05285.12 EKX41526.1 - 0.0059 16.1 20.0 0.017 14.6 11.5 2.1 2 0 0 2 2 2 2 SDA1 BUD22 PF09073.10 EKX41526.1 - 0.0062 15.9 12.7 0.016 14.6 6.3 2.1 2 0 0 2 2 2 1 BUD22 DUF2052 PF09747.9 EKX41526.1 - 0.012 15.8 15.8 0.49 10.5 6.7 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) RXT2_N PF08595.11 EKX41526.1 - 0.018 15.1 1.3 0.018 15.1 1.3 2.7 3 0 0 3 3 2 0 RXT2-like, N-terminal CPSF100_C PF13299.6 EKX41526.1 - 0.019 15.1 3.1 3.6 7.7 0.6 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RPA43_OB PF17875.1 EKX41526.1 - 0.044 14.4 8.3 1 10.0 0.4 2.7 3 0 0 3 3 2 0 RPA43 OB domain in RNA Pol I Mpp10 PF04006.12 EKX41526.1 - 0.055 11.9 19.2 0.11 10.9 11.0 2.1 2 0 0 2 2 2 0 Mpp10 protein NOA36 PF06524.12 EKX41526.1 - 0.056 12.8 27.0 0.15 11.4 19.2 2.2 2 0 0 2 2 2 0 NOA36 protein RPN2_C PF18004.1 EKX41526.1 - 0.08 12.9 8.4 0.27 11.1 0.6 2.4 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain MAM33 PF02330.16 EKX41526.1 - 0.11 12.5 14.3 0.96 9.3 6.1 2.2 2 0 0 2 2 2 0 Mitochondrial glycoprotein Nop14 PF04147.12 EKX41526.1 - 0.12 10.6 22.5 0.02 13.2 12.9 2.1 2 0 0 2 2 2 0 Nop14-like family Tim54 PF11711.8 EKX41526.1 - 0.12 11.1 4.4 1.3 7.7 0.2 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Afi1 PF07792.12 EKX41526.1 - 0.14 12.6 9.2 1.4 9.4 3.5 2.5 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Na_trans_assoc PF06512.13 EKX41526.1 - 0.15 12.4 9.8 0.28 11.5 5.3 2.3 2 0 0 2 2 2 0 Sodium ion transport-associated DUF5523 PF17661.1 EKX41526.1 - 0.15 11.8 17.4 0.11 12.2 1.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5523) Pes-10 PF07149.11 EKX41526.1 - 0.29 10.1 20.2 0.2 10.7 12.4 2.2 2 0 0 2 2 2 0 Pes-10 Vfa1 PF08432.10 EKX41526.1 - 0.58 10.5 9.0 2.2 8.6 2.4 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 RNA_pol_3_Rpc31 PF11705.8 EKX41526.1 - 0.62 10.3 33.2 2.4 8.4 22.6 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 SGT1 PF07093.11 EKX41526.1 - 0.78 8.1 12.1 0.0082 14.6 3.8 1.8 2 0 0 2 2 2 0 SGT1 protein CDC27 PF09507.10 EKX41526.1 - 0.81 9.0 24.9 2.4 7.4 10.8 2.5 2 1 0 2 2 2 0 DNA polymerase subunit Cdc27 PPP4R2 PF09184.11 EKX41526.1 - 1.3 8.6 23.9 1.3 8.6 16.0 2.4 2 0 0 2 2 2 0 PPP4R2 BSP_II PF05432.11 EKX41526.1 - 2.2 7.9 26.1 3.7 7.2 3.0 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) TFB6 PF17110.5 EKX41526.1 - 2.4 7.9 14.3 4.9 6.9 8.7 2.3 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH CDC45 PF02724.14 EKX41526.1 - 5.8 5.1 22.2 0.85 7.8 13.0 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF4484 PF14831.6 EKX41526.1 - 6.3 6.8 11.9 12 5.9 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) MPP6 PF10175.9 EKX41526.1 - 9.3 6.8 14.7 3.9 8.0 1.7 2.5 2 0 0 2 2 2 0 M-phase phosphoprotein 6 NHL PF01436.21 EKX41527.1 - 4.8e-23 80.0 6.8 6.7e-05 22.7 0.0 6.0 5 1 0 5 5 5 4 NHL repeat Arylesterase PF01731.20 EKX41527.1 - 0.0014 18.8 0.0 3.7 7.8 0.0 2.8 3 0 0 3 3 3 2 Arylesterase EF-hand_6 PF13405.6 EKX41528.1 - 1.9e-05 24.2 2.1 0.0041 16.9 0.6 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EKX41528.1 - 0.0001 22.7 0.7 0.062 13.8 0.1 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EKX41528.1 - 0.0038 17.1 0.2 0.1 12.5 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX41528.1 - 0.042 13.4 0.3 0.042 13.4 0.3 2.5 3 1 0 3 3 3 0 EF hand Glyco_tran_28_C PF04101.16 EKX41529.1 - 3.8e-05 23.7 0.0 7.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain MGDG_synth PF06925.11 EKX41529.1 - 0.0038 17.3 0.0 0.007 16.5 0.0 1.3 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Kelch_1 PF01344.25 EKX41530.1 - 1.6e-17 62.8 7.2 9.8e-09 34.7 0.0 5.1 4 1 1 5 5 5 3 Kelch motif Kelch_6 PF13964.6 EKX41530.1 - 1.8e-15 56.6 2.7 3.6e-07 30.2 0.0 5.1 4 1 1 5 5 5 4 Kelch motif Kelch_4 PF13418.6 EKX41530.1 - 6.5e-07 29.3 8.0 5.4e-05 23.1 0.0 4.0 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 EKX41530.1 - 7.1e-07 29.4 3.8 0.0045 17.2 0.0 4.4 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 EKX41530.1 - 9.7e-07 28.5 5.3 0.051 13.6 0.0 4.7 4 1 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 EKX41530.1 - 0.036 14.1 7.8 10 6.2 0.0 4.5 4 1 1 5 5 5 0 Kelch motif PDZ_6 PF17820.1 EKX41531.1 - 1.4e-12 47.2 0.2 3e-12 46.2 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX41531.1 - 2.4e-12 47.0 0.2 4.4e-12 46.2 0.2 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX41531.1 - 8.1e-08 32.5 0.1 1.6e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX41531.1 - 0.026 14.5 0.1 0.062 13.3 0.1 1.7 1 0 0 1 1 1 0 Tricorn protease PDZ domain RRM_1 PF00076.22 EKX41532.1 - 4.4e-20 71.3 0.1 0.00044 20.0 0.1 5.7 5 1 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EKX41532.1 - 4.5e-07 29.6 0.0 1 9.2 0.0 4.2 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM_9 PF18444.1 EKX41532.1 - 0.024 14.5 0.0 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif DUF4236 PF14020.6 EKX41532.1 - 0.068 13.8 0.7 0.17 12.5 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4236) Glyco_transf_5 PF08323.11 EKX41533.1 - 3e-68 230.1 0.0 5.5e-68 229.3 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EKX41533.1 - 3.4e-18 65.8 0.0 5.8e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EKX41533.1 - 1.7e-14 54.4 0.0 3.7e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EKX41533.1 - 0.073 13.5 0.1 0.75 10.2 0.1 2.3 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 EKX41533.1 - 0.091 12.8 0.1 0.93 9.5 0.0 2.5 2 1 0 2 2 2 0 Glycosyltransferase Family 4 Guanylate_cyc PF00211.20 EKX41534.1 - 1.7e-23 83.2 0.0 1.8e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ephrin_rec_like PF07699.13 EKX41536.1 - 4.4e-09 36.0 8.0 5.3e-06 26.1 3.9 2.9 2 0 0 2 2 2 2 Putative ephrin-receptor like RANK_CRD_2 PF18278.1 EKX41536.1 - 0.34 11.1 3.8 0.22 11.7 1.1 2.2 2 0 0 2 2 2 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 cEGF PF12662.7 EKX41536.1 - 2.9 7.9 11.1 5.8 7.0 1.7 2.8 2 0 0 2 2 2 0 Complement Clr-like EGF-like PDZ_6 PF17820.1 EKX41537.1 - 5.4e-09 35.8 0.0 0.0028 17.5 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 EKX41537.1 - 2.1e-07 31.2 0.0 0.015 15.6 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX41537.1 - 1.6e-05 25.1 0.0 0.013 15.8 0.0 3.1 3 0 0 3 3 3 2 PDZ domain Tricorn_PDZ PF14685.6 EKX41537.1 - 0.0089 16.0 0.0 1 9.4 0.0 2.4 2 0 0 2 2 2 1 Tricorn protease PDZ domain SRP40_C PF05022.12 EKX41538.1 - 5.1e-20 72.1 1.7 5.1e-20 72.1 1.7 3.2 3 1 1 4 4 4 1 SRP40, C-terminal domain LisH PF08513.11 EKX41538.1 - 0.012 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 LisH LAP1C PF05609.12 EKX41538.1 - 0.6 9.1 17.5 0.71 8.9 17.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Presenilin PF01080.17 EKX41538.1 - 2 7.1 14.3 2.3 6.9 14.3 1.3 1 0 0 1 1 1 0 Presenilin Suf PF05843.14 EKX41538.1 - 2.2 8.2 10.4 2.9 7.8 10.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Macoilin PF09726.9 EKX41538.1 - 2.9 6.3 17.5 3.4 6.1 17.5 1.1 1 0 0 1 1 1 0 Macoilin family Atrophin-1 PF03154.15 EKX41538.1 - 3.6 5.8 17.1 4.1 5.6 17.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF4776 PF16003.5 EKX41538.1 - 6.2 5.7 17.5 2.7 6.9 14.7 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4776) MPDZ_u10 PF16667.5 EKX41538.1 - 7 7.6 15.7 13 6.7 7.2 2.5 1 1 1 2 2 2 0 Unstructured region 10 on multiple PDZ protein Neur_chan_memb PF02932.16 EKX41538.1 - 8.3 6.4 8.9 12 5.8 8.9 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UBA PF00627.31 EKX41539.1 - 1.3e-08 34.5 0.2 4.3e-08 32.9 0.1 2.0 2 0 0 2 2 2 1 UBA/TS-N domain PB1 PF00564.24 EKX41539.1 - 0.052 13.5 0.0 3.3 7.7 0.0 2.7 2 0 0 2 2 2 0 PB1 domain RVT_1 PF00078.27 EKX41540.1 - 8.9e-08 31.9 0.0 3.5e-05 23.4 0.0 2.3 1 1 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) ORC5_C PF14630.6 EKX41540.1 - 0.012 15.1 0.2 0.029 13.9 0.2 1.6 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus Trigger_N PF05697.13 EKX41542.1 - 1.6e-29 103.0 0.1 2.3e-28 99.3 0.0 2.3 2 0 0 2 2 2 1 Bacterial trigger factor protein (TF) Trigger_C PF05698.14 EKX41542.1 - 1.2e-11 44.9 1.2 1.8e-11 44.3 0.3 1.7 2 0 0 2 2 2 1 Bacterial trigger factor protein (TF) C-terminus FKBP_C PF00254.28 EKX41542.1 - 2.8e-05 24.3 0.1 7.7e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase LepB_N PF18640.1 EKX41542.1 - 0.077 12.6 0.3 0.14 11.7 0.3 1.4 1 0 0 1 1 1 0 LepB N-terminal domain RF-1 PF00472.20 EKX41543.1 - 5.6e-24 84.3 2.5 1.1e-23 83.3 2.5 1.5 1 0 0 1 1 1 1 RF-1 domain LETM1 PF07766.13 EKX41544.1 - 2.3e-07 30.5 0.0 6.2e-07 29.0 0.0 1.6 2 0 0 2 2 2 1 LETM1-like protein N2227 PF07942.12 EKX41545.1 - 7.4e-48 163.1 0.0 1.1e-47 162.5 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 EKX41545.1 - 0.0073 16.2 0.0 0.0096 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX41545.1 - 0.045 14.5 0.0 0.14 12.9 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EKX41545.1 - 0.074 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family IDEAL PF08858.10 EKX41546.1 - 0.014 15.2 0.1 0.032 14.0 0.1 1.5 1 0 0 1 1 1 0 IDEAL domain cNMP_binding PF00027.29 EKX41547.1 - 1.1e-11 44.7 0.0 6.2e-11 42.2 0.0 2.2 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain WW PF00397.26 EKX41547.1 - 0.26 11.4 1.1 18 5.6 0.0 3.2 3 0 0 3 3 3 0 WW domain DUF4381 PF14316.6 EKX41549.1 - 0.04 14.2 0.1 0.065 13.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) SPICE PF15678.5 EKX41550.1 - 0.024 14.0 0.4 0.031 13.6 0.4 1.1 1 0 0 1 1 1 0 Centriole duplication and mitotic chromosome congression Filamin PF00630.19 EKX41551.1 - 2.5e-22 79.6 0.0 3.8e-11 43.7 0.0 2.0 1 1 1 2 2 2 2 Filamin/ABP280 repeat Invasin_D3 PF09134.10 EKX41551.1 - 1.1e-05 25.6 0.1 7.2e-05 23.0 0.1 2.0 1 1 1 2 2 2 1 Invasin, domain 3 Big_1 PF02369.16 EKX41551.1 - 0.0013 18.7 0.1 0.29 11.2 0.0 2.4 2 0 0 2 2 2 2 Bacterial Ig-like domain (group 1) Lipoprotein_17 PF04200.12 EKX41551.1 - 0.0013 19.0 2.3 0.59 10.5 0.1 2.4 1 1 0 2 2 2 2 Lipoprotein associated domain Neurexophilin PF06312.12 EKX41551.1 - 0.0064 16.0 0.1 0.078 12.4 0.1 2.1 2 0 0 2 2 2 1 Neurexophilin YtkA PF13115.6 EKX41551.1 - 0.031 14.9 0.0 2.3 8.9 0.0 2.4 2 1 0 2 2 2 0 YtkA-like DUF3244 PF11589.8 EKX41551.1 - 0.033 14.3 0.5 1 9.5 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3244) Big_3_5 PF16640.5 EKX41551.1 - 0.04 14.1 0.4 4.5 7.5 0.1 2.5 1 1 1 2 2 2 0 Bacterial Ig-like domain (group 3) Cbl_N3 PF02762.14 EKX41551.1 - 0.068 13.0 0.0 9.9 6.1 0.0 2.2 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, SH2-like domain SH2 PF00017.24 EKX41551.1 - 0.081 13.0 0.0 12 6.0 0.0 2.3 2 1 0 2 2 2 0 SH2 domain LysM PF01476.20 EKX41552.1 - 0.00077 19.5 1.7 0.0064 16.5 0.5 3.4 3 0 0 3 3 3 1 LysM domain ATP-synt_A PF00119.20 EKX41552.1 - 0.033 14.1 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 ATP synthase A chain PDZ_6 PF17820.1 EKX41553.1 - 7.3e-11 41.8 0.0 1.5e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX41553.1 - 4.8e-08 33.2 0.0 1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX41553.1 - 4.2e-07 30.2 0.5 7.8e-07 29.4 0.1 1.7 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 EKX41553.1 - 0.0011 18.9 0.0 0.0034 17.3 0.0 1.9 1 1 0 1 1 1 1 Tricorn protease PDZ domain SAM_2 PF07647.17 EKX41553.1 - 0.0026 17.8 0.1 0.0052 16.9 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EKX41553.1 - 0.0037 17.7 0.1 0.0085 16.5 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IncFII_repA PF02387.15 EKX41553.1 - 0.083 12.1 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 IncFII RepA protein family Acyltransferase PF01553.21 EKX41554.1 - 1.1e-24 86.6 0.0 1.7e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Abhydrolase_1 PF00561.20 EKX41555.1 - 1.3e-13 51.2 0.1 3.1e-13 50.0 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EKX41555.1 - 1.6e-13 51.8 0.0 2.2e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EKX41555.1 - 1e-06 28.2 0.0 1.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 EKX41555.1 - 0.024 13.7 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Fructosamin_kin PF03881.14 EKX41557.1 - 4.1e-19 68.9 5.1 5.2e-15 55.4 0.9 2.6 2 1 0 2 2 2 2 Fructosamine kinase FtsJ PF01728.19 EKX41558.1 - 1.1e-13 51.7 0.0 1.3e-13 51.5 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Zeta_toxin PF06414.12 EKX41559.1 - 3.1e-14 52.7 0.3 1.4e-13 50.6 0.1 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.6 EKX41559.1 - 0.0031 17.7 0.1 0.0075 16.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EKX41559.1 - 0.13 12.9 0.1 0.25 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain Tudor_3 PF18115.1 EKX41560.1 - 0.0052 16.6 0.1 1.4 8.9 0.0 2.4 2 0 0 2 2 2 2 DNA repair protein Crb2 Tudor domain Rep-A_N PF04057.12 EKX41560.1 - 0.17 11.9 0.1 0.62 10.1 0.0 1.8 2 0 0 2 2 2 0 Replication factor-A protein 1, N-terminal domain CLU PF13236.6 EKX41561.1 - 7.3e-19 68.5 0.0 1.3e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria LRR_6 PF13516.6 EKX41561.1 - 1.3e-11 43.5 10.8 0.14 12.3 0.0 9.0 9 0 0 9 9 9 3 Leucine Rich repeat eIF3_p135 PF12807.7 EKX41561.1 - 0.00052 20.1 1.6 0.00094 19.3 0.1 2.2 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 DSBA PF01323.20 EKX41561.1 - 0.013 15.3 0.4 0.61 9.8 0.1 2.9 2 1 0 2 2 2 0 DSBA-like thioredoxin domain Flg_hook PF02120.16 EKX41561.1 - 0.022 14.6 0.2 4.5 7.2 0.0 2.7 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK LRR_4 PF12799.7 EKX41561.1 - 0.025 15.0 19.6 2.3 8.8 0.1 8.0 7 1 1 8 8 8 0 Leucine Rich repeats (2 copies) Colipase-like PF15083.6 EKX41561.1 - 4.8 7.4 9.6 1.1 9.4 0.7 3.7 3 0 0 3 3 3 0 Colipase-like COG6 PF06419.11 EKX41562.1 - 3.9e-161 537.4 0.0 4.4e-161 537.2 0.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 RhoGEF PF00621.20 EKX41562.1 - 0.038 14.2 0.9 0.11 12.7 0.9 1.8 1 0 0 1 1 1 0 RhoGEF domain Exonuc_VII_L PF02601.15 EKX41562.1 - 0.92 9.0 5.8 0.088 12.4 1.4 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4004 PF13171.6 EKX41562.1 - 1.4 9.1 4.3 16 5.7 1.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4004) TauD PF02668.16 EKX41563.1 - 4.5e-38 131.6 0.1 6e-38 131.2 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 EKX41563.1 - 1.9e-06 27.2 0.0 2.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 CsiD DUF971 PF06155.12 EKX41563.1 - 0.0077 16.9 0.0 0.019 15.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF971) Mak10 PF04112.13 EKX41568.1 - 0.045 13.3 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase WD40 PF00400.32 EKX41571.1 - 8.1e-32 108.8 16.2 7.3e-07 29.8 0.4 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX41571.1 - 1.4e-08 34.9 0.7 0.025 14.9 0.0 3.2 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EKX41571.1 - 3e-06 26.8 3.5 0.00079 18.8 0.1 3.1 2 2 2 4 4 4 2 WD40-like domain Nup160 PF11715.8 EKX41571.1 - 9e-06 24.6 2.3 0.34 9.5 0.6 3.0 2 1 1 3 3 3 3 Nucleoporin Nup120/160 cwf18 PF08315.12 EKX41572.1 - 2.1e-24 86.7 2.4 2.4e-24 86.5 2.4 1.0 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor DMPK_coil PF08826.10 EKX41572.1 - 0.0093 16.1 0.1 0.021 14.9 0.1 1.6 1 1 0 1 1 1 1 DMPK coiled coil domain like BatD PF13584.6 EKX41572.1 - 0.037 12.9 0.4 0.04 12.7 0.4 1.0 1 0 0 1 1 1 0 Oxygen tolerance Homoserine_dh PF00742.19 EKX41573.1 - 1.6e-53 181.2 0.0 2.2e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EKX41573.1 - 2.9e-09 37.6 0.0 6.1e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain TPR_6 PF13174.6 EKX41574.1 - 0.05 14.2 0.0 0.088 13.5 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX41574.1 - 0.056 13.3 0.0 0.085 12.8 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 EKX41574.1 - 0.067 13.3 0.0 0.099 12.8 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX41574.1 - 0.081 13.2 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TruB_N PF01509.18 EKX41575.1 - 2.1e-43 148.2 0.0 3.5e-43 147.5 0.0 1.3 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EKX41575.1 - 5.5e-05 23.2 0.6 0.00019 21.5 0.2 2.1 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain Beta_helix PF13229.6 EKX41576.1 - 6.2e-08 32.6 1.0 2.3e-07 30.8 0.9 1.5 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 EKX41576.1 - 0.0012 18.2 0.1 0.0017 17.7 0.1 1.2 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Membralin PF09746.9 EKX41577.1 - 8.7 5.3 8.9 0.46 9.5 3.0 1.7 1 1 1 2 2 2 0 Tumour-associated protein Hydrolase_4 PF12146.8 EKX41578.1 - 0.00053 19.3 0.0 0.00076 18.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 EKX41578.1 - 0.003 17.4 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Peptidase_S9 PF00326.21 EKX41578.1 - 0.0082 15.6 0.0 0.026 14.0 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EKX41578.1 - 0.016 15.1 0.1 0.041 13.7 0.1 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 EKX41578.1 - 0.036 14.2 0.0 0.058 13.5 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_6 PF12697.7 EKX41578.1 - 0.042 14.4 0.0 0.044 14.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 EKX41578.1 - 0.06 13.1 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein FSH1 PF03959.13 EKX41578.1 - 0.065 12.9 0.0 0.079 12.6 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF2974 PF11187.8 EKX41578.1 - 0.18 11.3 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) ECH_1 PF00378.20 EKX41580.1 - 1.1e-85 287.0 0.6 1.3e-85 286.8 0.6 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EKX41580.1 - 1.7e-34 119.8 2.3 3.7e-32 112.2 0.6 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 EKX41580.1 - 0.0046 16.9 0.2 0.47 10.4 0.0 2.5 2 0 0 2 2 2 2 Peptidase family S49 Sox17_18_mid PF12067.8 EKX41581.1 - 0.0021 18.1 9.3 1.8 8.7 0.2 5.1 3 1 1 4 4 4 2 Sox 17/18 central domain GPS2_interact PF15784.5 EKX41581.1 - 0.021 15.2 3.3 0.048 14.1 3.3 1.6 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Atg14 PF10186.9 EKX41581.1 - 0.086 11.9 1.6 0.15 11.1 1.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sel1 PF08238.12 EKX41582.1 - 7.7e-24 83.6 18.1 0.00015 22.3 0.0 7.1 6 0 0 6 6 6 5 Sel1 repeat Inhibitor_I71 PF12628.7 EKX41582.1 - 0.26 11.1 2.7 0.48 10.2 2.7 1.4 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor PBP1_TM PF14812.6 EKX41582.1 - 0.59 10.5 17.7 1.7 9.1 17.7 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleo_P87 PF07267.11 EKX41582.1 - 3 6.6 15.1 5.7 5.7 15.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.14 EKX41582.1 - 3.4 5.9 14.2 4.9 5.3 14.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Arm PF00514.23 EKX41583.1 - 0.0011 18.9 0.1 0.003 17.5 0.1 1.8 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat TIR_2 PF13676.6 EKX41585.1 - 1.6e-05 25.5 0.1 0.00061 20.4 0.0 2.9 2 0 0 2 2 2 1 TIR domain RRM_1 PF00076.22 EKX41585.1 - 0.00026 20.8 0.0 0.024 14.5 0.0 2.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPRY PF00622.28 EKX41585.1 - 0.0011 19.1 0.0 0.0023 18.1 0.0 1.5 1 0 0 1 1 1 1 SPRY domain DUF1722 PF08349.11 EKX41585.1 - 0.11 12.8 0.3 19 5.6 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Occludin_ELL PF07303.13 EKX41585.1 - 0.47 11.2 4.2 1.6 9.5 0.0 3.5 3 0 0 3 3 3 0 Occludin homology domain FapA PF03961.13 EKX41585.1 - 0.66 8.5 4.2 0.25 9.9 1.2 1.7 2 0 0 2 2 2 0 Flagellar Assembly Protein A Prefoldin_2 PF01920.20 EKX41585.1 - 5.1 7.1 10.5 15 5.6 0.6 4.0 4 0 0 4 4 4 0 Prefoldin subunit RmuC PF02646.16 EKX41585.1 - 5.4 6.1 10.5 0.72 8.9 3.1 2.9 3 0 0 3 3 3 0 RmuC family PI_PP_I PF18363.1 EKX41586.1 - 0.032 14.4 5.6 0.039 14.1 1.0 2.8 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain DUF3008 PF11450.8 EKX41586.1 - 0.37 11.0 4.6 0.67 10.2 0.2 3.0 2 0 0 2 2 2 0 Protein of unknwon function (DUF3008) Tiam_CC_Ex PF18385.1 EKX41586.1 - 0.98 9.8 8.1 0.15 12.4 1.4 2.7 1 1 2 3 3 3 0 T-lymphoma invasion and metastasis CC-Ex domain DASH_Dam1 PF08653.10 EKX41586.1 - 4.8 7.1 6.3 1.1 9.1 0.9 2.8 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF16 PF01519.16 EKX41586.1 - 5.4 7.6 20.7 0.11 13.0 6.2 3.2 2 2 0 2 2 2 0 Protein of unknown function DUF16 OmpH PF03938.14 EKX41586.1 - 6.3 7.1 34.8 1.3 9.3 6.3 4.2 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) cNMP_binding PF00027.29 EKX41587.1 - 3.3e-23 81.6 0.7 1.2e-10 41.3 0.1 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Septin PF00735.18 EKX41589.1 - 3.2e-33 115.2 0.0 4.2e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EKX41589.1 - 1.9e-07 31.1 0.0 2.8e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EKX41589.1 - 9.3e-05 22.9 0.0 0.00012 22.5 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EKX41589.1 - 0.00013 21.9 1.8 0.003 17.5 1.0 2.6 2 1 0 2 2 2 1 RsgA GTPase Ras PF00071.22 EKX41589.1 - 0.0036 16.9 0.0 0.0057 16.3 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EKX41589.1 - 0.0037 17.5 0.0 0.0057 16.9 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 EKX41589.1 - 0.011 15.3 0.2 0.018 14.5 0.2 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 EKX41589.1 - 0.028 14.7 0.0 0.064 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EKX41589.1 - 0.044 13.0 0.1 0.24 10.6 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 EKX41589.1 - 0.049 13.3 0.1 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EKX41589.1 - 0.051 13.3 1.0 0.72 9.6 0.3 2.7 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 EKX41589.1 - 0.13 12.1 0.1 0.35 10.6 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EKX41589.1 - 0.15 12.6 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_35 PF14516.6 EKX41589.1 - 0.17 10.7 0.1 0.31 9.8 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain Tudor_3 PF18115.1 EKX41590.1 - 0.00042 20.1 0.0 0.00065 19.5 0.0 1.3 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain TUDOR_5 PF18359.1 EKX41590.1 - 0.00098 18.8 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain 1 53-BP1_Tudor PF09038.10 EKX41590.1 - 0.0042 17.0 0.0 0.0081 16.1 0.0 1.4 1 0 0 1 1 1 1 Tumour suppressor p53-binding protein-1 Tudor SBF_like PF13593.6 EKX41590.1 - 0.0076 15.6 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) TIG PF01833.24 EKX41591.1 - 7.3e-66 218.3 83.0 1.9e-10 40.6 2.6 14.5 13 1 1 14 14 14 14 IPT/TIG domain PDZ_6 PF17820.1 EKX41591.1 - 1.5e-05 24.8 0.0 0.1 12.5 0.0 3.6 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 EKX41591.1 - 0.0019 18.5 0.0 3.1 8.2 0.0 2.9 2 0 0 2 2 2 2 PDZ domain 2OG-FeII_Oxy_3 PF13640.6 EKX41592.1 - 8.7e-15 55.4 0.0 1.2e-14 54.9 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EKX41592.1 - 0.0018 18.7 0.0 0.0029 18.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Coprogen_oxidas PF01218.18 EKX41594.1 - 1.4e-116 388.4 0.0 1.6e-116 388.2 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Neuropeptide_S PF14993.6 EKX41595.1 - 0.07 13.0 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 Neuropeptide S precursor protein NifQ PF04891.12 EKX41596.1 - 7.9 6.8 5.8 11 6.4 0.4 3.1 4 0 0 4 4 4 0 NifQ CENP-T_C PF15511.6 EKX41598.1 - 4.1e-09 36.5 0.1 5e-09 36.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EKX41598.1 - 0.0001 22.6 0.1 0.00014 22.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 EKX41598.1 - 0.0001 22.4 0.2 0.00014 21.9 0.2 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 EKX41598.1 - 0.00021 21.7 0.3 0.00024 21.5 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EKX41598.1 - 0.00042 20.5 0.1 0.00064 19.9 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EKX41598.1 - 0.0072 16.4 0.0 0.0085 16.2 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EKX41598.1 - 0.013 15.5 0.1 0.02 14.9 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated Abhydrolase_2 PF02230.16 EKX41599.1 - 4.4e-49 167.2 0.0 5.4e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EKX41599.1 - 4.4e-05 22.9 0.1 0.00063 19.1 0.0 2.4 3 0 0 3 3 3 1 Serine aminopeptidase, S33 DLH PF01738.18 EKX41599.1 - 0.00024 20.8 0.0 0.00033 20.3 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 EKX41599.1 - 0.0013 18.7 0.1 0.005 16.7 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EKX41599.1 - 0.0019 18.8 2.9 0.0044 17.7 3.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 EKX41599.1 - 0.013 15.1 0.0 0.11 12.1 0.0 2.3 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Esterase PF00756.20 EKX41599.1 - 0.015 15.0 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative esterase PGAP1 PF07819.13 EKX41599.1 - 0.15 11.8 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 PGAP1-like protein NMT1 PF09084.11 EKX41600.1 - 1.9e-07 31.2 0.0 2.5e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EKX41600.1 - 3.4e-06 26.9 0.1 1.8e-05 24.6 0.1 1.9 1 1 1 2 2 2 1 NMT1-like family Phosphonate-bd PF12974.7 EKX41600.1 - 0.00061 19.5 0.0 0.00076 19.1 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_3 PF16868.5 EKX41600.1 - 0.00087 18.8 0.0 0.0025 17.3 0.0 1.6 1 1 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 EKX41600.1 - 0.0016 17.9 0.0 0.0037 16.7 0.0 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 AAA_12 PF13087.6 EKX41601.1 - 1.8e-53 181.1 0.0 2.4e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EKX41601.1 - 9.7e-24 84.5 0.2 1.7e-23 83.8 0.2 1.3 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EKX41601.1 - 0.14 12.0 0.0 0.37 10.6 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 EKX41601.1 - 0.15 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EKX41602.1 - 2.5e-15 57.0 0.1 2.9e-15 56.8 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EKX41602.1 - 1.6e-09 37.7 0.3 1.9e-09 37.6 0.3 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EKX41602.1 - 1.3e-07 32.0 0.3 1.6e-07 31.8 0.3 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EKX41602.1 - 0.00087 19.7 0.0 0.001 19.5 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 EKX41602.1 - 0.006 15.7 0.0 0.006 15.7 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.16 EKX41602.1 - 0.0098 15.4 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein HEM4 PF02602.15 EKX41602.1 - 0.01 15.2 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD AAA_22 PF13401.6 EKX41602.1 - 0.011 16.0 0.3 0.017 15.4 0.2 1.6 1 1 0 1 1 1 0 AAA domain DUF853 PF05872.12 EKX41602.1 - 0.013 14.1 0.1 0.017 13.8 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_5 PF07728.14 EKX41602.1 - 0.025 14.6 0.2 0.091 12.8 0.1 1.8 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EKX41602.1 - 0.03 14.3 0.2 0.044 13.7 0.2 1.3 1 0 0 1 1 1 0 NACHT domain AAA_6 PF12774.7 EKX41602.1 - 0.033 13.2 0.1 0.04 12.9 0.1 1.1 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA PF00004.29 EKX41602.1 - 0.037 14.5 0.1 0.046 14.1 0.1 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 EKX41602.1 - 0.041 13.9 0.0 0.049 13.6 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 EKX41602.1 - 0.046 14.3 0.1 0.075 13.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 EKX41602.1 - 0.06 13.1 0.1 0.074 12.8 0.1 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase Hydin_ADK PF17213.3 EKX41602.1 - 0.08 13.2 0.1 0.1 12.9 0.1 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF2075 PF09848.9 EKX41602.1 - 0.085 12.1 0.1 0.092 12.0 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) HSP70 PF00012.20 EKX41604.1 - 1.3e-250 832.8 9.6 1.5e-250 832.6 9.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EKX41604.1 - 3.1e-18 65.7 0.4 2.7e-16 59.3 0.1 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 EKX41604.1 - 0.005 17.3 4.2 1.3 9.5 0.3 3.5 3 1 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 EKX41604.1 - 0.0065 15.8 2.0 0.33 10.2 0.2 2.9 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase DUF2200 PF09966.9 EKX41604.1 - 0.0085 16.2 4.7 0.016 15.4 1.4 2.8 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2200) EcoR124_C PF12008.8 EKX41604.1 - 0.034 13.8 0.2 0.034 13.8 0.2 2.4 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal DUF2031 PF09592.10 EKX41604.1 - 0.048 13.2 0.3 0.048 13.2 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2031) CENP-X PF09415.10 EKX41604.1 - 0.53 10.6 3.4 0.65 10.4 1.4 2.2 2 0 0 2 2 2 0 CENP-S associating Centromere protein X APG6_N PF17675.1 EKX41604.1 - 2.2 8.8 10.9 6.5 7.3 5.4 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region Snf7 PF03357.21 EKX41604.1 - 3.5 7.2 15.5 26 4.4 10.9 3.2 3 0 0 3 3 3 0 Snf7 NUDIX PF00293.28 EKX41607.1 - 0.0017 18.4 0.3 1.3 9.0 0.0 2.3 2 0 0 2 2 2 2 NUDIX domain THB PF18362.1 EKX41607.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Tri-helix bundle domain EF_TS PF00889.19 EKX41608.1 - 9.5e-54 182.2 1.9 1.2e-53 181.8 1.9 1.1 1 0 0 1 1 1 1 Elongation factor TS UBA PF00627.31 EKX41608.1 - 0.01 15.7 0.0 0.025 14.5 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain FPN1 PF06963.12 EKX41609.1 - 1.6e-29 102.8 20.7 7.2e-17 61.1 11.9 2.1 2 0 0 2 2 2 2 Ferroportin1 (FPN1) MYO10_CC PF16735.5 EKX41611.1 - 1.8 8.7 19.9 56 3.9 0.2 7.4 1 1 8 9 9 9 0 Unconventional myosin-X coiled coil domain Peptidase_C78 PF07910.13 EKX41612.1 - 2.4e-39 135.0 0.0 2.8e-39 134.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 EKX41612.1 - 0.0048 16.3 0.8 0.0098 15.3 0.4 1.7 1 1 1 2 2 2 1 Peptidase family C54 CENP-T_C PF15511.6 EKX41614.1 - 1e-08 35.2 0.2 1.3e-08 34.9 0.2 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EKX41614.1 - 6.1e-05 23.3 0.6 9.4e-05 22.7 0.6 1.5 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 EKX41614.1 - 9.3e-05 22.8 0.5 0.00011 22.6 0.5 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EKX41614.1 - 0.00028 21.0 0.3 0.00038 20.6 0.3 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.15 EKX41614.1 - 0.0016 18.5 0.0 0.0021 18.1 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EKX41614.1 - 0.0042 17.1 0.1 0.0069 16.4 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 EKX41614.1 - 0.0056 16.9 0.1 0.0076 16.5 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Atu4866 PF11512.8 EKX41615.1 - 0.12 12.7 0.0 0.19 12.2 0.0 1.2 1 0 0 1 1 1 0 Agrobacterium tumefaciens protein Atu4866 peroxidase PF00141.23 EKX41621.1 - 3.1e-32 112.1 0.0 5.8e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 Peroxidase AdoMet_MTase PF07757.13 EKX41622.1 - 2e-32 111.9 0.2 3.7e-32 111.0 0.2 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_31 PF13847.6 EKX41622.1 - 0.0016 18.2 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EKX41622.1 - 0.0021 18.0 0.1 0.0072 16.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 EKX41622.1 - 0.038 13.6 0.0 0.076 12.6 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TehB PF03848.14 EKX41622.1 - 0.17 11.3 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Flavin_Reduct PF01613.18 EKX41623.1 - 0.00059 19.9 0.0 0.00073 19.6 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Caa3_CtaG PF09678.10 EKX41623.1 - 0.05 13.1 0.0 0.066 12.7 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) peroxidase PF00141.23 EKX41624.1 - 1.9e-43 148.8 0.0 2.6e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 Peroxidase Rieske PF00355.26 EKX41625.1 - 6.9e-13 48.4 0.1 1.1e-12 47.8 0.1 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 EKX41625.1 - 7.9e-12 45.0 0.0 9.5e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Glyco_transf_8 PF01501.20 EKX41626.1 - 3.4e-07 30.1 0.7 8.3e-06 25.5 0.7 2.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EKX41626.1 - 5.2e-05 22.7 0.0 6.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.16 EKX41626.1 - 0.0085 16.1 0.0 0.031 14.2 0.0 1.9 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase CTC1 PF15489.6 EKX41626.1 - 0.063 10.8 0.2 0.099 10.1 0.1 1.4 2 0 0 2 2 2 0 CST, telomere maintenance, complex subunit CTC1 Ion_trans PF00520.31 EKX41627.1 - 5.1e-38 130.7 20.2 8.7e-38 129.9 20.2 1.3 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EKX41627.1 - 0.00022 20.0 14.2 0.00055 18.7 14.2 1.6 1 1 0 1 1 1 1 Polycystin cation channel DOT1 PF08123.13 EKX41628.1 - 1.6e-09 37.6 0.3 2.5e-09 37.0 0.3 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 CDC45 PF02724.14 EKX41628.1 - 0.0027 16.1 10.8 0.0032 15.9 10.8 1.1 1 0 0 1 1 1 1 CDC45-like protein DNA_pol_phi PF04931.13 EKX41628.1 - 0.011 13.9 36.3 0.015 13.5 36.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 EKX41628.1 - 0.043 12.0 21.4 0.055 11.7 21.4 1.1 1 0 0 1 1 1 0 Nop14-like family ASRT PF07100.11 EKX41628.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Anabaena sensory rhodopsin transducer Mpp10 PF04006.12 EKX41628.1 - 0.27 9.6 14.4 0.37 9.2 14.4 1.1 1 0 0 1 1 1 0 Mpp10 protein CobT PF06213.12 EKX41628.1 - 0.35 10.2 18.5 0.52 9.7 18.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2457 PF10446.9 EKX41628.1 - 0.37 9.9 40.7 0.66 9.0 40.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 EKX41628.1 - 0.38 10.1 21.9 0.58 9.5 21.9 1.3 1 0 0 1 1 1 0 SDA1 TFIIA PF03153.13 EKX41628.1 - 0.81 9.6 23.0 0.98 9.3 23.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 EKX41628.1 - 1.5 8.1 16.8 2.1 7.6 16.8 1.2 1 0 0 1 1 1 0 BUD22 Sigma70_ner PF04546.13 EKX41628.1 - 1.8 8.4 18.7 4.1 7.2 18.7 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region TFB6 PF17110.5 EKX41628.1 - 2.7 7.7 11.3 4.4 7.0 11.3 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH PPP4R2 PF09184.11 EKX41628.1 - 6.7 6.2 19.9 10 5.6 19.9 1.3 1 0 0 1 1 1 0 PPP4R2 RNA_pol_3_Rpc31 PF11705.8 EKX41628.1 - 8.9 6.5 30.6 37 4.5 30.8 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Beta_helix PF13229.6 EKX41629.1 - 1.4e-11 44.5 23.2 1.5e-09 37.9 5.2 2.3 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 EKX41629.1 - 0.00081 18.7 1.0 0.00081 18.7 1.0 2.3 1 1 1 2 2 2 1 Periplasmic copper-binding protein (NosD) Aldo_ket_red PF00248.21 EKX41630.1 - 2.3e-34 119.0 0.0 2.6e-34 118.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF5500 PF17604.2 EKX41630.1 - 0.049 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5500) Cas_Cas4 PF01930.17 EKX41630.1 - 0.15 12.2 0.1 0.27 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF83 MCM2_N PF12619.8 EKX41630.1 - 0.17 12.2 1.5 0.27 11.5 1.5 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 Fringe PF02434.16 EKX41631.1 - 5.8e-11 42.3 0.0 2.2e-10 40.4 0.0 2.0 1 1 0 1 1 1 1 Fringe-like Uteroglobin PF01099.17 EKX41631.1 - 0.042 14.2 0.2 0.091 13.1 0.2 1.6 1 0 0 1 1 1 0 Uteroglobin family LRR_9 PF14580.6 EKX41632.1 - 2.6e-11 43.3 0.6 1.9e-05 24.2 0.1 2.6 2 0 0 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 EKX41632.1 - 3.3e-11 42.8 1.6 0.00019 21.1 0.0 3.8 3 0 0 3 3 3 2 Leucine rich repeat WD40 PF00400.32 EKX41632.1 - 5.8e-07 30.1 1.5 0.84 10.6 0.0 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX41632.1 - 2.9e-06 27.5 0.0 4.8 7.6 0.0 4.5 2 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain LRR_6 PF13516.6 EKX41632.1 - 1.2e-05 24.9 9.0 0.0021 18.0 0.0 6.4 6 0 0 6 6 6 1 Leucine Rich repeat LRR_4 PF12799.7 EKX41632.1 - 0.00011 22.4 11.6 0.039 14.4 0.2 5.2 3 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX41632.1 - 0.00048 20.1 1.8 0.33 10.9 0.2 2.5 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EKX41632.1 - 3 8.7 8.2 1.2e+02 3.8 0.8 5.5 5 0 0 5 5 5 0 Leucine Rich Repeat Ammonium_transp PF00909.21 EKX41634.1 - 2.5e-49 168.1 18.6 1.8e-48 165.2 18.6 1.8 1 1 0 1 1 1 1 Ammonium Transporter Family DUF2207 PF09972.9 EKX41634.1 - 2.1 7.0 5.1 0.56 8.9 0.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Alpha_kinase PF02816.18 EKX41635.1 - 7e-18 65.4 0.0 1e-17 64.9 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family PDZ_6 PF17820.1 EKX41635.1 - 6.5e-12 45.1 0.6 3.6e-11 42.7 0.3 2.2 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX41635.1 - 2e-05 24.8 0.2 4.1e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX41635.1 - 0.00017 21.8 0.0 0.0004 20.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Pes-10 PF07149.11 EKX41635.1 - 0.7 8.9 3.4 0.92 8.5 3.4 1.1 1 0 0 1 1 1 0 Pes-10 ENTH PF01417.20 EKX41637.1 - 3.5e-39 133.7 0.1 4.8e-39 133.3 0.1 1.2 1 0 0 1 1 1 1 ENTH domain VHS PF00790.19 EKX41637.1 - 8.7e-05 22.4 0.2 0.00014 21.7 0.2 1.3 1 0 0 1 1 1 1 VHS domain ANTH PF07651.16 EKX41637.1 - 0.0011 18.0 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 ANTH domain MBOAT PF03062.19 EKX41639.1 - 1.4e-05 24.6 4.5 2.4e-05 23.8 4.5 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT PF03062.19 EKX41640.1 - 1.4e-17 64.1 14.9 1.7e-17 63.8 14.9 1.1 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family LETM1 PF07766.13 EKX41641.1 - 0.023 14.0 0.1 0.091 12.1 0.0 1.8 2 0 0 2 2 2 0 LETM1-like protein PTPA PF03095.15 EKX41643.1 - 3.2e-114 381.5 0.0 3.7e-114 381.2 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Flavin_Reduct PF01613.18 EKX41644.1 - 0.022 14.8 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Flavin reductase like domain Androgen_recep PF02166.16 EKX41644.1 - 0.066 12.0 7.5 0.034 13.0 2.8 2.1 2 0 0 2 2 2 0 Androgen receptor WW PF00397.26 EKX41645.1 - 8.6e-10 38.5 4.0 2e-09 37.4 4.0 1.7 1 0 0 1 1 1 1 WW domain TPR_7 PF13176.6 EKX41645.1 - 0.033 14.2 4.1 7 6.9 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF789 PF05623.12 EKX41647.1 - 7.1e-23 81.7 0.3 6.9e-13 48.9 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF789) cwf21 PF08312.12 EKX41648.1 - 1.4e-12 47.5 8.4 1.4e-12 47.5 8.4 3.1 3 1 0 3 3 3 1 cwf21 domain KN17_SH3 PF18131.1 EKX41648.1 - 0.064 13.4 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 KN17 SH3-like C-terminal domain CENP-N PF05238.13 EKX41648.1 - 1.3 8.3 11.3 1.5 8.0 11.3 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like NPR3 PF03666.13 EKX41648.1 - 9.5 4.9 14.3 12 4.6 14.3 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pkinase_Tyr PF07714.17 EKX41649.1 - 4.3e-50 170.4 0.0 5.3e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX41649.1 - 2.2e-43 148.6 0.0 2.7e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EKX41649.1 - 0.0032 16.8 0.0 0.0052 16.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EKX41649.1 - 0.0096 14.7 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase MORN PF02493.20 EKX41650.1 - 4.6e-29 98.5 61.4 8.8e-08 31.6 3.5 8.8 9 0 0 9 9 9 7 MORN repeat WD40 PF00400.32 EKX41651.1 - 7.7e-08 32.9 3.4 0.00019 22.2 0.3 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat VID27 PF08553.10 EKX41651.1 - 0.051 12.6 0.0 0.065 12.3 0.0 1.1 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain ANAPC4_WD40 PF12894.7 EKX41651.1 - 0.099 13.0 0.0 0.27 11.5 0.0 1.8 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain P22_AR_N PF10547.9 EKX41652.1 - 0.074 13.4 0.0 0.091 13.1 0.0 1.3 1 1 0 1 1 1 0 P22_AR N-terminal domain PIN_12 PF16289.5 EKX41654.1 - 0.00016 22.3 0.7 0.00018 22.0 0.7 1.1 1 0 0 1 1 1 1 PIN domain Metallophos PF00149.28 EKX41655.1 - 1.1e-23 84.9 0.3 1.4e-23 84.5 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ion_trans PF00520.31 EKX41656.1 - 1e-31 110.0 22.7 1.4e-31 109.6 22.7 1.2 1 0 0 1 1 1 1 Ion transport protein PH PF00169.29 EKX41656.1 - 2.7e-06 27.8 0.0 6.6e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 PH domain PKD_channel PF08016.12 EKX41656.1 - 9.1e-05 21.3 7.5 9.1e-05 21.3 7.5 2.1 1 1 1 2 2 2 1 Polycystin cation channel EF-hand_6 PF13405.6 EKX41656.1 - 0.00059 19.6 2.9 0.005 16.7 0.4 3.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 EKX41656.1 - 0.048 14.1 3.7 0.11 12.9 3.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair DUF5305 PF17231.2 EKX41656.1 - 0.19 11.1 1.0 0.29 10.5 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5305) STAT1_TAZ2bind PF12162.8 EKX41656.1 - 0.7 9.5 2.3 57 3.4 0.2 3.3 3 0 0 3 3 3 0 STAT1 TAZ2 binding domain EF-hand_1 PF00036.32 EKX41656.1 - 1.2 8.8 6.7 0.4 10.3 0.8 3.2 3 0 0 3 3 3 0 EF hand IF2_assoc PF08364.11 EKX41657.1 - 0.032 14.5 1.3 0.13 12.6 1.3 2.1 1 1 0 1 1 1 0 Bacterial translation initiation factor IF-2 associated region DUF2254 PF10011.9 EKX41659.1 - 0.12 11.2 0.2 0.12 11.1 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) PPP4R2 PF09184.11 EKX41661.1 - 5.7e-20 72.1 0.0 7.2e-20 71.7 0.0 1.0 1 0 0 1 1 1 1 PPP4R2 Gly_acyl_tr_C PF08444.10 EKX41663.1 - 0.07 13.4 0.3 0.54 10.5 0.1 2.4 1 1 2 3 3 3 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region TBCA PF02970.16 EKX41663.1 - 0.14 12.5 3.7 0.83 10.0 3.5 2.2 1 1 0 1 1 1 0 Tubulin binding cofactor A Methyltr_RsmB-F PF01189.17 EKX41667.1 - 7.5e-30 104.1 0.0 4.4e-29 101.6 0.0 2.0 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EKX41667.1 - 0.034 14.3 0.0 0.054 13.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Aldedh PF00171.22 EKX41668.1 - 4.1e-168 559.7 1.8 4.6e-168 559.5 1.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EKX41668.1 - 0.013 15.0 0.0 0.11 11.9 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Mog1 PF04603.12 EKX41670.1 - 1e-26 94.0 0.1 1.7e-26 93.2 0.1 1.3 1 0 0 1 1 1 1 Ran-interacting Mog1 protein DUF550 PF04447.12 EKX41671.1 - 9.8e-05 22.4 0.0 17 5.6 0.0 3.8 4 0 0 4 4 4 3 Protein of unknown function (DUF550) Mo-co_dimer PF03404.16 EKX41671.1 - 0.00047 20.2 3.1 12 5.9 0.0 4.2 1 1 3 4 4 4 3 Mo-co oxidoreductase dimerisation domain Beta-Casp PF10996.8 EKX41673.1 - 3.3e-28 98.2 0.0 5.8e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 EKX41673.1 - 3.7e-22 78.7 0.1 1.2e-21 77.1 0.1 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain CPSF73-100_C PF11718.8 EKX41673.1 - 1.6e-20 73.6 0.0 3.7e-20 72.4 0.0 1.6 1 1 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term RMMBL PF07521.12 EKX41673.1 - 2.1e-17 62.8 0.1 4.2e-17 61.8 0.1 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 EKX41673.1 - 3.8e-15 56.4 0.0 5.8e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 EKX41673.1 - 1.3e-06 28.4 0.0 5.3e-06 26.4 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 EKX41673.1 - 3.8e-06 26.5 0.1 4.4e-05 23.1 0.0 2.4 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 EKX41673.1 - 1.2e-05 24.7 0.1 2.2e-05 23.8 0.1 1.5 1 1 0 1 1 1 1 Putative beta-lactamase-like family RWP-RK PF02042.15 EKX41674.1 - 4.2e-17 61.8 0.1 7.8e-17 61.0 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_Mga PF08280.11 EKX41674.1 - 0.0043 17.1 0.1 0.008 16.2 0.1 1.4 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain RWP-RK PF02042.15 EKX41675.1 - 4e-09 36.3 0.4 8.3e-09 35.3 0.4 1.5 1 0 0 1 1 1 1 RWP-RK domain WD40 PF00400.32 EKX41676.1 - 4e-25 87.6 25.8 5.6e-06 27.0 3.4 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.12 EKX41676.1 - 1.8e-16 60.4 0.1 3.7e-16 59.4 0.1 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 EKX41676.1 - 0.00018 21.7 0.7 0.031 14.6 0.4 3.7 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Inh PF02974.14 EKX41676.1 - 0.022 14.8 1.5 0.2 11.8 0.2 2.5 2 0 0 2 2 2 0 Protease inhibitor Inh Nup160 PF11715.8 EKX41676.1 - 0.042 12.5 3.1 2.6 6.6 0.2 3.7 1 1 2 4 4 4 0 Nucleoporin Nup120/160 Methyltransf_32 PF13679.6 EKX41678.1 - 6.1e-09 36.1 1.5 4.9e-08 33.1 1.5 2.1 1 1 0 1 1 1 1 Methyltransferase domain PKD_channel PF08016.12 EKX41680.1 - 4e-55 187.2 15.0 1.6e-54 185.2 15.0 1.7 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 EKX41680.1 - 6.9e-09 35.3 18.8 1e-08 34.7 18.8 1.2 1 0 0 1 1 1 1 Ion transport protein NPV_P10 PF05531.12 EKX41680.1 - 0.32 11.5 1.2 8.7 6.9 0.2 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 EKX41681.1 - 0.01 15.9 10.3 0.18 11.9 3.7 3.3 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.8 EKX41681.1 - 0.019 15.1 13.0 0.019 15.1 13.0 3.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TMEM89 PF15098.6 EKX41681.1 - 0.15 12.2 0.5 0.33 11.1 0.5 1.5 1 0 0 1 1 1 0 TMEM89 protein family SpecificRecomb PF10136.9 EKX41681.1 - 0.21 9.9 6.8 0.3 9.4 6.8 1.4 1 0 0 1 1 1 0 Site-specific recombinase DUF1664 PF07889.12 EKX41681.1 - 0.25 11.4 8.5 0.37 10.8 5.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Cob_adeno_trans PF01923.18 EKX41682.1 - 2.1e-58 197.1 0.1 2.5e-58 196.9 0.1 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase Neuroparsin PF07327.11 EKX41682.1 - 0.14 12.6 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 Neuroparsin WHIM1 PF15612.6 EKX41683.1 - 8.5e-05 22.0 0.6 8.5e-05 22.0 0.6 1.9 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 LptC PF06835.13 EKX41683.1 - 0.0087 15.7 0.2 0.019 14.6 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide-assembly, LptC-related IBR PF01485.21 EKX41683.1 - 2.2 8.6 9.8 0.52 10.6 3.3 2.7 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain DUF745 PF05335.13 EKX41684.1 - 1.2 8.8 10.9 2.2 7.9 10.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) THUMP PF02926.17 EKX41685.1 - 6.4e-12 45.8 0.1 9.8e-12 45.2 0.1 1.4 1 0 0 1 1 1 1 THUMP domain UBA PF00627.31 EKX41686.1 - 4.1e-05 23.4 0.0 0.00011 22.0 0.0 1.8 2 0 0 2 2 2 1 UBA/TS-N domain Helicase_C PF00271.31 EKX41686.1 - 0.00076 19.8 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX41686.1 - 0.016 15.2 5.7 1.3 9.0 0.0 3.7 3 1 1 4 4 4 0 Type III restriction enzyme, res subunit EF-hand_6 PF13405.6 EKX41686.1 - 0.03 14.2 0.2 0.087 12.8 0.2 1.8 1 0 0 1 1 1 0 EF-hand domain CTNNB1_binding PF08347.11 EKX41686.1 - 0.058 13.6 9.4 0.019 15.1 4.7 2.1 2 0 0 2 2 2 0 N-terminal CTNNB1 binding EF-hand_1 PF00036.32 EKX41686.1 - 0.14 11.7 0.9 0.31 10.7 0.9 1.6 1 0 0 1 1 1 0 EF hand Roughex PF06020.11 EKX41686.1 - 1.6 7.8 15.2 3.6 6.6 15.2 1.6 1 0 0 1 1 1 0 Drosophila roughex protein Rtf2 PF04641.12 EKX41686.1 - 3.8 6.8 9.8 6.1 6.1 9.8 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Presenilin PF01080.17 EKX41686.1 - 9.4 4.9 9.7 15 4.3 9.7 1.2 1 0 0 1 1 1 0 Presenilin Pro_isomerase PF00160.21 EKX41687.1 - 1.2e-23 84.1 0.0 1.9e-23 83.5 0.0 1.3 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Not3 PF04065.15 EKX41688.1 - 0.007 15.8 0.4 0.0094 15.4 0.4 1.1 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component FAD_binding_3 PF01494.19 EKX41689.1 - 8.2e-15 54.9 3.6 8.1e-08 31.9 0.0 3.1 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EKX41689.1 - 5e-06 26.6 0.4 1.2e-05 25.4 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EKX41689.1 - 0.0005 19.4 0.3 0.0013 18.0 0.4 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EKX41689.1 - 0.00084 19.0 0.2 0.0014 18.3 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DnaJ_CXXCXGXG PF00684.19 EKX41689.1 - 0.0016 18.7 1.3 0.0047 17.3 1.3 1.8 1 0 0 1 1 1 1 DnaJ central domain Pyr_redox PF00070.27 EKX41689.1 - 0.003 18.1 0.5 0.019 15.5 0.6 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 EKX41689.1 - 0.008 16.4 0.8 0.018 15.2 0.8 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EKX41689.1 - 0.026 14.4 1.3 0.026 14.4 1.3 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 EKX41689.1 - 0.027 13.6 1.2 0.043 12.9 1.2 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_Gly3P_dh_N PF01210.23 EKX41689.1 - 0.04 13.9 0.2 0.083 12.9 0.2 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.6 EKX41689.1 - 0.042 13.1 0.1 0.07 12.4 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 EKX41689.1 - 0.15 12.7 0.6 0.43 11.2 0.6 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF4105 PF13387.6 EKX41689.1 - 0.17 11.5 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) IlvN PF07991.12 EKX41689.1 - 0.19 11.3 0.6 0.38 10.3 0.6 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 EKX41689.1 - 0.2 11.0 1.1 0.37 10.1 1.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EKX41689.1 - 0.35 9.9 1.4 0.57 9.2 1.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Anti-TRAP PF15777.5 EKX41689.1 - 2.1 8.4 5.0 24 5.0 0.4 2.4 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Ebp2 PF05890.12 EKX41690.1 - 0.004 16.8 5.5 0.0077 15.8 5.5 1.4 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 UBA2_C PF16195.5 EKX41690.1 - 0.014 16.1 3.7 0.018 15.7 1.8 2.2 2 0 0 2 2 2 0 SUMO-activating enzyme subunit 2 C-terminus PGA2 PF07543.12 EKX41690.1 - 1.7 8.6 8.2 3.9 7.4 8.2 1.7 1 0 0 1 1 1 0 Protein trafficking PGA2 Ank_2 PF12796.7 EKX41691.1 - 3.4e-24 85.2 1.3 2.2e-12 47.4 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EKX41691.1 - 3.8e-21 74.5 10.4 1.8e-06 28.1 0.1 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 EKX41691.1 - 5.1e-21 74.8 9.3 2.4e-10 40.7 0.6 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX41691.1 - 9.2e-17 59.4 9.5 0.0013 19.0 0.1 5.6 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 EKX41691.1 - 4.8e-13 49.1 11.9 3.9e-05 23.8 0.4 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) DUF2723 PF11028.8 EKX41692.1 - 7.8e-35 120.3 5.6 1.6e-34 119.3 5.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2723) PMT_2 PF13231.6 EKX41692.1 - 2.5e-06 27.8 7.6 2.5e-06 27.8 7.6 2.3 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Phage_C PF12025.8 EKX41692.1 - 0.14 12.1 0.0 0.49 10.3 0.0 1.9 1 0 0 1 1 1 0 Phage protein C Cir_N PF10197.9 EKX41693.1 - 0.016 15.3 12.0 0.016 15.3 12.0 2.4 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR Ribosomal_60s PF00428.19 EKX41693.1 - 0.05 14.2 5.5 0.93 10.1 0.4 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein HSP70 PF00012.20 EKX41693.1 - 0.16 10.1 5.6 0.18 10.0 5.6 1.0 1 0 0 1 1 1 0 Hsp70 protein DUF4710 PF15828.5 EKX41693.1 - 2.1 8.5 11.1 7.1 6.8 5.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) Sec62 PF03839.16 EKX41693.1 - 3.8 7.0 7.7 4.5 6.7 7.7 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 SGP PF17228.2 EKX41694.1 - 5.2 8.0 18.5 0.11 13.3 7.6 2.2 2 0 0 2 2 2 0 Sulphur globule protein CK2S PF15011.6 EKX41695.1 - 0.06 13.2 0.0 0.069 13.0 0.0 1.1 1 0 0 1 1 1 0 Casein Kinase 2 substrate RVT_1 PF00078.27 EKX41696.1 - 0.00012 21.7 0.1 0.017 14.6 0.1 2.6 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ion_trans_2 PF07885.16 EKX41697.1 - 2.7e-13 49.7 1.1 2.7e-13 49.7 1.1 3.0 2 1 1 3 3 3 1 Ion channel SK_channel PF03530.14 EKX41697.1 - 7.6e-06 25.9 0.9 7.6e-06 25.9 0.9 2.5 2 0 0 2 2 2 1 Calcium-activated SK potassium channel Ion_trans PF00520.31 EKX41697.1 - 0.2 10.9 13.7 1.5 8.0 13.7 2.5 1 1 0 1 1 1 0 Ion transport protein Transglut_core2 PF13369.6 EKX41698.1 - 2.9e-39 134.1 0.0 4.9e-39 133.4 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily Peptidase_S49_N PF08496.10 EKX41700.1 - 3.4e-15 56.4 1.3 4.6e-14 52.8 0.2 2.5 2 1 0 2 2 2 1 Peptidase family S49 N-terminal GHMP_kinases_N PF00288.26 EKX41700.1 - 0.22 11.8 3.3 0.55 10.5 3.3 1.6 1 0 0 1 1 1 0 GHMP kinases N terminal domain DUF3500 PF12006.8 EKX41700.1 - 0.29 10.6 1.0 4.4 6.7 0.0 2.5 2 1 0 3 3 3 0 Protein of unknown function (DUF3500) LRR_6 PF13516.6 EKX41701.1 - 5.5e-22 75.9 12.2 0.00017 21.4 0.0 9.1 8 0 0 8 8 8 5 Leucine Rich repeat Methyltransf_16 PF10294.9 EKX41701.1 - 1e-20 74.2 0.0 3.8e-15 56.0 0.0 2.6 1 1 1 2 2 2 2 Lysine methyltransferase LRR_4 PF12799.7 EKX41701.1 - 1.4e-08 34.9 10.7 0.097 13.1 0.9 6.4 4 1 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX41701.1 - 0.00031 20.4 19.6 5.6 6.8 9.7 6.1 6 1 0 7 7 5 1 Leucine rich repeat DUF2722 PF10846.8 EKX41701.1 - 0.00057 19.0 8.8 0.14 11.0 4.4 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) LRR_1 PF00560.33 EKX41701.1 - 0.0028 18.0 20.1 9.4 7.2 0.0 7.9 9 1 0 9 9 6 0 Leucine Rich Repeat Methyltransf_23 PF13489.6 EKX41701.1 - 0.0056 16.5 0.0 0.0056 16.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MAM33 PF02330.16 EKX41701.1 - 0.011 15.8 9.5 0.82 9.6 0.2 2.2 2 0 0 2 2 2 0 Mitochondrial glycoprotein MTS PF05175.14 EKX41701.1 - 0.018 14.6 0.0 0.043 13.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Atrophin-1 PF03154.15 EKX41701.1 - 0.024 13.0 4.7 0.043 12.1 4.7 1.3 1 0 0 1 1 1 0 Atrophin-1 family Methyltransf_25 PF13649.6 EKX41701.1 - 0.091 13.5 0.0 0.24 12.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 EKX41701.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein LRR_9 PF14580.6 EKX41701.1 - 0.13 11.7 0.6 0.84 9.1 0.3 2.3 2 1 0 2 2 2 0 Leucine-rich repeat PIP5K PF01504.18 EKX41701.1 - 0.22 10.7 1.5 0.66 9.2 0.6 2.0 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase CDC45 PF02724.14 EKX41701.1 - 0.29 9.4 4.7 0.2 9.9 1.9 1.8 2 0 0 2 2 2 0 CDC45-like protein CTU2 PF10288.9 EKX41701.1 - 0.3 11.3 4.0 1.9 8.7 0.7 2.4 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Suf PF05843.14 EKX41701.1 - 0.38 10.7 5.7 10 6.0 0.1 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Trypan_PARP PF05887.11 EKX41701.1 - 0.38 10.7 2.3 0.99 9.4 2.3 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) EIIBC-GUT_N PF03612.14 EKX41701.1 - 0.84 9.4 9.4 1 9.1 3.8 2.4 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus FRQ PF09421.10 EKX41701.1 - 0.98 7.4 3.3 1.5 6.7 3.3 1.2 1 0 0 1 1 1 0 Frequency clock protein Bud13 PF09736.9 EKX41701.1 - 1.4 9.3 21.3 0.18 12.2 8.8 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Med15 PF09606.10 EKX41701.1 - 1.5 7.4 19.0 1.8 7.1 6.1 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal MPM1 PF17234.2 EKX41701.1 - 3 8.1 11.3 2.4 8.4 4.0 2.2 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 CPSF100_C PF13299.6 EKX41701.1 - 3.2 7.9 9.1 7.7 6.7 4.1 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF3371 PF11851.8 EKX41701.1 - 4.1 8.5 8.8 4.9 8.3 1.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) EPL1 PF10513.9 EKX41701.1 - 4.1 7.8 12.9 3 8.2 5.0 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like Eapp_C PF10238.9 EKX41701.1 - 4.5 7.3 9.7 4.1 7.5 3.1 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein RPA43_OB PF17875.1 EKX41701.1 - 7 7.3 11.0 10 6.8 5.3 2.3 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I SpoIIP PF07454.11 EKX41701.1 - 7.6 5.9 11.6 1.3 8.4 3.8 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Metallothi_Euk2 PF12809.7 EKX41702.1 - 3.5 8.0 30.5 1.4 9.3 2.4 3.6 1 1 3 4 4 4 0 Eukaryotic metallothionein Phage_int_SAM_2 PF12834.7 EKX41703.1 - 0.91 10.3 2.9 15 6.3 0.1 3.1 1 1 3 4 4 4 0 Phage integrase, N-terminal Metallothi_Euk2 PF12809.7 EKX41703.1 - 4.1 7.7 29.9 1.1 9.6 2.2 3.7 1 1 3 4 4 4 0 Eukaryotic metallothionein NAD_binding_4 PF07993.12 EKX41704.1 - 2.3e-67 226.9 0.0 2.9e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.19 EKX41704.1 - 2.1e-15 56.7 0.0 4.3e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EKX41704.1 - 2.4e-07 30.5 0.1 3e-06 26.9 0.1 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EKX41704.1 - 0.027 13.5 0.1 0.44 9.5 0.1 2.7 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EKX41704.1 - 0.087 11.9 0.0 0.25 10.4 0.0 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EKX41704.1 - 0.1 12.0 0.4 0.79 9.0 0.1 2.5 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase FPN1 PF06963.12 EKX41705.1 - 3.2e-19 68.8 27.9 9.7e-18 63.9 9.7 3.5 4 0 0 4 4 4 2 Ferroportin1 (FPN1) Peptidase_C14 PF00656.22 EKX41706.1 - 1.4e-08 35.0 0.0 2.4e-07 30.9 0.0 2.2 1 1 1 2 2 2 2 Caspase domain Caudo_bapla16 PF16792.5 EKX41706.1 - 0.13 11.2 0.2 0.19 10.7 0.2 1.2 1 0 0 1 1 1 0 Phage tail base-plate attachment protein of Caudovirales ORF16 Kinesin PF00225.23 EKX41707.1 - 1.7e-95 319.8 0.0 1.7e-95 319.8 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EKX41707.1 - 2.6e-22 79.4 0.2 1.4e-21 77.0 0.0 2.4 2 1 1 3 3 3 1 Microtubule binding Apolipoprotein PF01442.18 EKX41707.1 - 0.03 14.2 0.4 0.03 14.2 0.4 5.0 4 2 1 5 5 5 0 Apolipoprotein A1/A4/E domain Fib_alpha PF08702.10 EKX41707.1 - 0.034 14.3 0.4 0.034 14.3 0.4 4.3 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family DUF4727 PF15856.5 EKX41707.1 - 0.083 12.5 0.5 0.45 10.1 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4727) DnaB_bind PF10410.9 EKX41707.1 - 0.78 10.0 8.3 0.056 13.6 0.7 3.0 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase DUF4094 PF13334.6 EKX41707.1 - 1.7 9.1 10.7 20 5.7 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4094) EF-hand_13 PF17958.1 EKX41709.1 - 1.9e-36 123.7 0.1 2.8e-35 120.0 0.1 2.6 2 1 1 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 EKX41709.1 - 5.7e-19 68.3 5.0 8e-17 61.5 0.4 3.4 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX41709.1 - 1.4e-09 37.1 3.4 0.00012 21.7 0.0 4.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 EKX41709.1 - 1.6e-06 27.2 1.2 0.0012 18.3 0.0 3.6 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 EKX41709.1 - 0.00025 20.4 0.0 0.0019 17.6 0.0 2.4 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.9 EKX41709.1 - 0.019 15.3 0.7 6 7.2 0.1 2.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 EKX41709.1 - 0.022 14.6 0.9 0.11 12.3 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair LsmAD PF06741.13 EKX41710.1 - 0.027 15.0 0.0 0.051 14.1 0.0 1.5 1 0 0 1 1 1 0 LsmAD domain TPR_14 PF13428.6 EKX41711.1 - 8.9e-31 104.0 26.3 9e-05 23.0 0.1 10.9 4 2 7 11 11 11 8 Tetratricopeptide repeat TPR_17 PF13431.6 EKX41711.1 - 1.5e-27 94.0 10.8 0.00028 21.1 0.0 10.4 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_2 PF07719.17 EKX41711.1 - 2e-24 83.7 18.1 0.0014 18.6 0.1 11.4 12 0 0 12 12 11 5 Tetratricopeptide repeat TPR_16 PF13432.6 EKX41711.1 - 1.3e-20 73.7 5.9 5.1e-06 27.0 0.0 5.4 5 1 0 5 5 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 EKX41711.1 - 2e-20 73.1 6.5 0.00012 22.5 0.1 5.7 3 3 1 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.6 EKX41711.1 - 2.1e-15 56.1 2.4 0.21 11.3 0.0 8.7 7 2 2 9 9 9 4 TPR repeat TPR_12 PF13424.6 EKX41711.1 - 2.1e-14 53.6 27.2 0.021 15.1 0.0 9.2 5 3 4 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.6 EKX41711.1 - 5.9e-14 51.0 10.5 0.078 13.2 0.0 10.0 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX41711.1 - 8.2e-12 44.4 7.0 0.18 11.7 0.1 9.0 10 0 0 10 10 9 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EKX41711.1 - 5.2e-09 36.2 0.9 0.085 12.8 0.0 6.7 8 1 0 8 8 8 1 Mad3/BUB1 homology region 1 TPR_15 PF13429.6 EKX41711.1 - 1.3e-08 34.4 16.3 0.02 14.1 0.2 5.4 3 1 2 5 5 5 3 Tetratricopeptide repeat NARP1 PF12569.8 EKX41711.1 - 1.5e-06 27.4 0.2 0.44 9.4 0.0 3.6 3 1 1 4 4 4 3 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 EKX41711.1 - 5.5e-06 26.4 10.7 0.0074 16.4 0.1 5.4 4 2 2 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX41711.1 - 6.6e-06 26.3 2.0 1.1 9.5 0.0 4.3 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 Suf PF05843.14 EKX41711.1 - 2.7e-05 24.3 0.0 0.024 14.6 0.0 3.5 2 1 0 2 2 2 1 Suppressor of forked protein (Suf) TPR_6 PF13174.6 EKX41711.1 - 4e-05 24.0 12.9 12 6.7 0.1 8.6 9 0 0 9 9 8 0 Tetratricopeptide repeat FAT PF02259.23 EKX41711.1 - 0.0025 17.1 3.5 0.89 8.7 1.9 3.7 1 1 0 2 2 2 1 FAT domain TPR_10 PF13374.6 EKX41711.1 - 0.0042 16.9 24.0 0.3 11.0 0.4 8.6 9 0 0 9 9 8 1 Tetratricopeptide repeat MIT PF04212.18 EKX41711.1 - 0.011 15.8 1.5 60 3.8 0.0 5.5 5 1 1 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 EKX41711.1 - 0.031 14.6 7.0 12 6.3 0.2 4.4 3 2 1 4 4 4 0 Tetratricopeptide repeat DUF4192 PF13830.6 EKX41711.1 - 0.053 13.6 0.8 0.16 12.0 0.4 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4192) DUF3808 PF10300.9 EKX41711.1 - 0.068 11.9 0.1 2.6 6.7 0.1 2.5 1 1 1 3 3 3 0 Protein of unknown function (DUF3808) TPR_21 PF09976.9 EKX41711.1 - 0.24 11.1 7.8 19 4.9 0.1 5.4 3 2 1 5 5 5 0 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 EKX41711.1 - 0.74 10.6 19.9 6.2 7.8 0.0 6.8 8 0 0 8 8 5 0 Tetratricopeptide repeat PRA-PH PF01503.17 EKX41712.1 - 4.7e-18 65.4 2.6 2.8e-09 37.3 0.1 2.7 2 1 0 2 2 2 2 Phosphoribosyl-ATP pyrophosphohydrolase FlgT_C PF16538.5 EKX41712.1 - 0.00055 20.4 0.0 2.3 8.8 0.0 2.6 3 0 0 3 3 3 2 Flagellar assembly protein T, C-terminal domain DUF3877 PF12993.7 EKX41712.1 - 0.0014 18.5 0.4 0.081 12.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function, E. rectale Gene description (DUF3877) MazG PF03819.17 EKX41712.1 - 0.0021 18.2 0.7 0.66 10.2 0.1 2.4 2 0 0 2 2 2 2 MazG nucleotide pyrophosphohydrolase domain Bac_DNA_binding PF00216.21 EKX41712.1 - 0.073 13.3 0.1 29 5.0 0.0 3.0 3 0 0 3 3 3 0 Bacterial DNA-binding protein YWFCY PF14293.6 EKX41712.1 - 0.11 12.8 0.9 21 5.5 0.1 2.4 2 0 0 2 2 2 0 YWFCY protein Acyl_transf_3 PF01757.22 EKX41713.1 - 1.5e-16 60.4 44.0 2e-16 60.0 44.0 1.1 1 0 0 1 1 1 1 Acyltransferase family PIRT PF15099.6 EKX41713.1 - 0.25 10.9 0.1 0.25 10.9 0.1 2.6 3 1 0 3 3 3 0 Phosphoinositide-interacting protein family Peptidase_C2 PF00648.21 EKX41715.1 - 1.2e-103 346.2 0.0 4e-60 203.3 0.0 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease ClpS PF02617.17 EKX41716.1 - 1.6e-09 37.4 0.2 2.3e-09 36.9 0.2 1.2 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS AOX PF01786.17 EKX41717.1 - 1.2e-65 221.1 0.1 1.6e-65 220.8 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase BPL_N PF09825.9 EKX41718.1 - 0.058 12.5 0.0 0.058 12.5 0.0 2.7 2 1 1 3 3 3 0 Biotin-protein ligase, N terminal Ycf1 PF05758.12 EKX41718.1 - 0.88 7.4 2.7 1.2 6.9 2.7 1.1 1 0 0 1 1 1 0 Ycf1 Serinc PF03348.15 EKX41718.1 - 1.1 8.1 5.0 1.8 7.4 5.0 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Tim54 PF11711.8 EKX41718.1 - 2 7.1 14.4 0.021 13.6 6.2 1.8 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Eapp_C PF10238.9 EKX41718.1 - 3.2 7.8 9.6 12 6.0 9.6 1.9 1 0 0 1 1 1 0 E2F-associated phosphoprotein PBP_sp32 PF07222.12 EKX41718.1 - 4.7 6.6 18.6 12 5.2 18.6 1.7 1 0 0 1 1 1 0 Proacrosin binding protein sp32 AAA_23 PF13476.6 EKX41718.1 - 5.4 7.5 24.0 1.3 9.5 12.2 3.2 3 0 0 3 3 3 0 AAA domain Amidohydro_1 PF01979.20 EKX41719.1 - 1.1e-07 31.5 0.0 2.2e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EKX41719.1 - 0.00017 21.2 0.0 0.00028 20.5 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family ATP-grasp_3 PF02655.14 EKX41719.1 - 0.045 13.8 0.0 0.19 11.7 0.0 2.0 1 1 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.6 EKX41719.1 - 0.15 11.3 0.0 0.33 10.2 0.0 1.5 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp GOLGA2L5 PF15070.6 EKX41720.1 - 0.0038 16.0 1.4 0.022 13.4 0.0 2.0 2 0 0 2 2 2 1 Putative golgin subfamily A member 2-like protein 5 WASH-7_C PF14746.6 EKX41720.1 - 0.033 13.9 0.9 0.071 12.8 0.9 1.5 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal SRAP PF02586.14 EKX41721.1 - 1.6e-35 122.7 0.2 4.1e-17 62.5 0.0 3.2 2 1 0 2 2 2 2 SOS response associated peptidase (SRAP) DUF563 PF04577.14 EKX41722.1 - 6.7e-21 75.4 0.1 5.4e-20 72.4 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF563) ADH_zinc_N_2 PF13602.6 EKX41723.1 - 2.5e-14 54.4 0.1 2.6e-13 51.2 0.0 2.4 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EKX41723.1 - 8.6e-13 48.4 0.0 2.5e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EKX41723.1 - 0.00052 19.9 0.1 0.0025 17.7 0.1 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 EKX41723.1 - 0.0066 15.8 0.2 0.011 15.1 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.21 EKX41723.1 - 0.017 14.9 0.1 0.024 14.3 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Eno-Rase_NADH_b PF12242.8 EKX41723.1 - 0.076 12.8 0.3 0.17 11.7 0.3 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PDZ_2 PF13180.6 EKX41724.1 - 5.3e-11 42.7 0.0 1.9e-06 28.1 0.1 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EKX41724.1 - 2.3e-09 36.9 0.0 1.2e-07 31.5 0.0 2.6 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX41724.1 - 4.1e-07 30.2 0.0 6.4e-05 23.2 0.0 2.5 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 EKX41724.1 - 0.00013 21.8 0.0 0.0016 18.3 0.0 2.6 2 0 0 2 2 2 1 Tricorn protease PDZ domain DUF905 PF06006.12 EKX41725.1 - 0.023 14.7 2.2 0.17 11.9 0.5 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF905) Sec20 PF03908.13 EKX41725.1 - 0.24 11.3 0.4 0.44 10.5 0.4 1.4 1 0 0 1 1 1 0 Sec20 Transket_pyr PF02779.24 EKX41726.1 - 1.4e-69 233.3 0.0 2.3e-69 232.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 EKX41726.1 - 1.9e-67 227.3 0.0 2.8e-67 226.8 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 EKX41726.1 - 1.6e-50 170.7 0.0 2.8e-50 170.0 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 EKX41726.1 - 4.2e-11 42.2 2.9 1.1e-10 40.9 2.9 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus R2K_2 PF18299.1 EKX41726.1 - 0.036 13.9 0.1 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain, R2K clade family 2 SPRY PF00622.28 EKX41727.1 - 0.00049 20.2 0.2 0.00083 19.5 0.2 1.4 1 0 0 1 1 1 1 SPRY domain HepII_C PF18675.1 EKX41727.1 - 0.036 14.1 0.0 0.15 12.2 0.0 2.0 1 1 1 2 2 2 0 Heparinase II C-terminal domain CHASE4 PF05228.13 EKX41728.1 - 0.097 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 CHASE4 domain BRI3BP PF14965.6 EKX41728.1 - 0.12 11.9 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 Negative regulator of p53/TP53 FAM167 PF11652.8 EKX41729.1 - 0.05 14.1 2.0 1 9.9 0.1 3.0 2 0 0 2 2 2 0 FAM167 RecR PF02132.15 EKX41729.1 - 0.15 11.6 1.0 6 6.5 0.0 2.6 2 0 0 2 2 2 0 RecR protein UPF0240 PF06784.11 EKX41729.1 - 0.85 9.7 4.5 0.67 10.0 1.8 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0240) NAD_binding_10 PF13460.6 EKX41730.1 - 1.7e-25 90.0 0.0 2.3e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EKX41730.1 - 0.00029 20.3 0.0 0.00044 19.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 EKX41730.1 - 0.071 12.7 0.0 0.18 11.4 0.0 1.7 1 1 0 1 1 1 0 NmrA-like family Methyltransf_16 PF10294.9 EKX41731.1 - 1.5e-19 70.4 0.0 2e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 EKX41731.1 - 0.08 12.3 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Mut7-C PF01927.16 EKX41732.1 - 7.1e-29 100.8 0.0 2e-28 99.4 0.0 1.7 1 0 0 1 1 1 1 Mut7-C RNAse domain DNA_pol_A_exo1 PF01612.20 EKX41732.1 - 2e-16 60.2 0.0 4.4e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease tRNA_edit PF04073.15 EKX41732.1 - 1.3e-06 28.4 0.1 3.1e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain ATG27 PF09451.10 EKX41732.1 - 0.0067 16.3 0.2 0.037 13.9 0.1 2.1 2 0 0 2 2 2 1 Autophagy-related protein 27 DUF5615 PF18480.1 EKX41732.1 - 0.089 12.6 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) GerD PF17898.1 EKX41732.1 - 0.16 12.0 0.0 1.2 9.2 0.0 2.2 1 1 1 2 2 2 0 Spore germination GerD central core domain Pkinase PF00069.25 EKX41733.1 - 1.3e-36 126.4 0.0 2.8e-36 125.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX41733.1 - 5.4e-22 78.3 0.0 1.8e-21 76.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX41733.1 - 0.14 11.4 0.1 0.66 9.2 0.1 1.8 1 1 0 1 1 1 0 Kinase-like RWP-RK PF02042.15 EKX41734.1 - 2.5e-12 46.5 0.0 3.9e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX41734.1 - 0.022 14.5 0.0 0.18 11.6 0.0 2.3 2 1 1 3 3 3 0 Bacterial regulatory protein, Fis family Methyltransf_16 PF10294.9 EKX41735.1 - 1.3e-13 51.1 0.0 1.4e-05 24.9 0.0 2.2 1 1 1 2 2 2 2 Lysine methyltransferase Arm PF00514.23 EKX41736.1 - 1.8e-08 34.1 1.0 0.65 10.1 0.0 5.7 5 0 0 5 5 5 4 Armadillo/beta-catenin-like repeat C2 PF00168.30 EKX41736.1 - 6e-06 26.5 0.1 5.1e-05 23.5 0.1 2.5 1 1 0 1 1 1 1 C2 domain Ribosomal_S21e PF01249.18 EKX41737.1 - 4.2e-36 122.9 0.1 4.9e-36 122.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Vps16_C PF04840.12 EKX41738.1 - 0.13 11.3 0.1 0.2 10.7 0.1 1.1 1 0 0 1 1 1 0 Vps16, C-terminal region Iso_dh PF00180.20 EKX41739.1 - 5.7e-137 456.5 0.0 6.5e-137 456.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PA26 PF04636.13 EKX41740.1 - 5 5.9 17.1 1.3 7.8 5.2 2.1 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) DnaJ_CXXCXGXG PF00684.19 EKX41741.1 - 3.7e-05 24.0 10.9 0.031 14.6 10.0 2.8 1 1 2 3 3 3 3 DnaJ central domain FYVE PF01363.21 EKX41741.1 - 7.5 6.8 11.0 1.1 9.4 5.7 2.2 1 1 1 2 2 2 0 FYVE zinc finger Sirohm_synth_M PF14824.6 EKX41742.1 - 0.19 11.2 2.0 10 5.7 0.3 2.4 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central DDRGK PF09756.9 EKX41742.1 - 3.5 7.2 8.1 0.14 11.7 1.2 2.0 1 1 0 2 2 2 0 DDRGK domain zf-RING_2 PF13639.6 EKX41743.1 - 4.2e-09 36.6 9.0 4.2e-09 36.6 9.0 2.6 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX41743.1 - 1.2e-05 25.1 8.6 1.2e-05 25.1 8.6 3.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 EKX41743.1 - 1.3e-05 25.0 13.3 1.3e-05 25.0 13.3 3.1 2 1 1 3 3 3 1 PHD-finger zf-C3HC4 PF00097.25 EKX41743.1 - 8.3e-05 22.4 8.5 8.3e-05 22.4 8.5 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EKX41743.1 - 0.00011 21.9 8.7 0.00011 21.9 8.7 2.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 EKX41743.1 - 0.0011 18.8 6.8 0.0011 18.8 6.8 3.7 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EKX41743.1 - 0.0089 16.2 8.9 0.0089 16.2 8.9 3.8 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING IBR PF01485.21 EKX41743.1 - 0.041 14.1 6.7 0.041 14.1 6.7 3.4 3 1 0 3 3 3 0 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 EKX41743.1 - 0.05 13.6 3.5 0.05 13.6 3.5 3.7 2 2 1 3 3 3 0 RING-type zinc-finger Ank_2 PF12796.7 EKX41744.1 - 5.2e-08 33.4 0.0 0.23 12.1 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX41744.1 - 1e-06 28.5 0.4 0.63 10.8 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 EKX41744.1 - 4.6e-05 23.7 0.4 0.47 11.0 0.0 4.6 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 EKX41744.1 - 0.069 13.8 0.0 18 6.1 0.0 3.8 4 1 0 4 4 4 0 Ankyrin repeats (many copies) FF PF01846.19 EKX41745.1 - 0.07 13.3 0.3 0.19 12.0 0.3 1.7 1 0 0 1 1 1 0 FF domain Tup_N PF08581.10 EKX41745.1 - 1.3 9.4 6.3 0.23 11.8 1.9 2.0 2 0 0 2 2 2 0 Tup N-terminal DUF2508 PF10704.9 EKX41745.1 - 3.6 7.8 5.6 33 4.8 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2508) LRR_6 PF13516.6 EKX41746.1 - 2.1e-08 33.5 29.8 0.39 10.9 0.0 10.1 13 0 0 13 13 13 4 Leucine Rich repeat LRR_4 PF12799.7 EKX41746.1 - 2.5e-08 34.1 17.0 0.22 12.0 0.0 6.9 6 2 2 8 8 8 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX41746.1 - 0.00065 19.9 9.0 2.1e+02 3.2 0.0 8.2 8 2 0 8 8 8 0 Leucine Rich Repeat Ebp2 PF05890.12 EKX41746.1 - 0.073 12.6 0.2 0.11 12.0 0.2 1.2 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 LRR_8 PF13855.6 EKX41746.1 - 0.11 12.3 0.0 0.11 12.3 0.0 6.3 6 3 1 7 7 7 0 Leucine rich repeat Kinesin PF00225.23 EKX41747.1 - 3e-11 42.8 9.4 1.8e-06 27.2 0.0 4.2 4 0 0 4 4 4 2 Kinesin motor domain Shugoshin_N PF07558.11 EKX41747.1 - 4.3e-05 23.3 5.2 0.0003 20.6 2.6 2.8 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Csm1_N PF18504.1 EKX41747.1 - 0.036 14.4 0.4 0.036 14.4 0.4 5.5 3 1 3 6 6 6 0 Csm1 N-terminal domain Macoilin PF09726.9 EKX41747.1 - 0.043 12.4 38.0 0.06 11.9 38.0 1.1 1 0 0 1 1 1 0 Macoilin family Androgen_recep PF02166.16 EKX41747.1 - 0.7 8.7 11.8 1.2 7.9 11.8 1.3 1 0 0 1 1 1 0 Androgen receptor Asparaginase_2 PF01112.18 EKX41747.1 - 2.3 7.2 9.9 0.49 9.4 4.1 2.2 2 0 0 2 2 2 0 Asparaginase BCS1_N PF08740.11 EKX41748.1 - 2.7e-31 109.0 0.0 3.5e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EKX41748.1 - 2.7e-22 79.6 0.0 6.5e-22 78.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX41748.1 - 2.4e-05 24.8 0.1 0.00011 22.6 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 EKX41748.1 - 5.4e-05 22.5 0.0 9.3e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EKX41748.1 - 0.0012 18.8 0.0 0.0024 17.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EKX41748.1 - 0.0015 18.8 0.0 0.014 15.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EKX41748.1 - 0.0018 18.1 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EKX41748.1 - 0.0059 16.8 0.0 0.017 15.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EKX41748.1 - 0.0095 16.2 0.0 0.036 14.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EKX41748.1 - 0.012 15.2 0.1 0.029 13.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EKX41748.1 - 0.015 15.8 0.0 0.036 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EKX41748.1 - 0.015 14.6 0.0 0.1 11.9 0.0 2.0 1 1 1 2 2 2 0 KaiC AAA_24 PF13479.6 EKX41748.1 - 0.016 15.0 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EKX41748.1 - 0.02 14.7 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 EKX41748.1 - 0.053 12.7 0.0 0.082 12.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 EKX41748.1 - 0.082 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EKX41748.1 - 0.095 13.1 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 EKX41748.1 - 0.14 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EKX41748.1 - 0.14 12.6 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 EKX41748.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_6 PF12774.7 EKX41748.1 - 0.16 10.9 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region IstB_IS21 PF01695.17 EKX41748.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Cpn10 PF00166.21 EKX41749.1 - 9.1e-29 99.4 0.0 1e-28 99.2 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit TPR_9 PF13371.6 EKX41751.1 - 0.0034 17.5 0.1 0.011 15.9 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX41751.1 - 0.01 15.9 2.6 0.47 10.7 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX41751.1 - 0.07 13.4 0.1 0.21 11.9 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 EKX41751.1 - 0.088 12.7 4.7 0.29 11.1 0.4 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Malt_amylase_C PF16657.5 EKX41751.1 - 0.12 12.5 0.4 16 5.7 0.0 4.1 4 1 1 5 5 5 0 Maltogenic Amylase, C-terminal domain RcbX PF02341.15 EKX41752.1 - 2.3e-08 34.2 0.6 1.7 8.9 0.1 4.3 4 0 0 4 4 4 4 RbcX protein Frigida PF07899.11 EKX41752.1 - 0.09 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Frigida-like protein CRM1_C PF08767.11 EKX41752.1 - 0.1 11.8 0.0 2.4 7.2 0.0 2.2 2 0 0 2 2 2 0 CRM1 C terminal MFS_1 PF07690.16 EKX41753.1 - 2.9e-48 164.6 49.9 7.7e-47 159.9 44.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EKX41753.1 - 1.4e-05 24.2 33.9 7.4e-05 21.8 33.9 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter Band_7 PF01145.25 EKX41754.1 - 3.1e-28 99.0 1.0 3.1e-28 99.0 1.0 1.8 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 EKX41754.1 - 2.5e-22 78.7 0.2 7.6e-22 77.1 0.2 1.9 1 0 0 1 1 1 1 C-terminal region of band_7 Band_7_1 PF13421.6 EKX41754.1 - 0.012 15.3 0.1 0.022 14.5 0.1 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family TOM20_plant PF06552.12 EKX41756.1 - 3.3e-05 23.7 0.2 0.023 14.4 0.0 2.3 2 0 0 2 2 2 2 Plant specific mitochondrial import receptor subunit TOM20 HD_4 PF13328.6 EKX41757.1 - 0.034 13.9 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 HD domain SARAF PF06682.12 EKX41758.1 - 0.018 14.7 0.3 0.021 14.5 0.3 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SieB PF14163.6 EKX41758.1 - 0.018 14.6 0.2 0.024 14.1 0.2 1.2 1 0 0 1 1 1 0 Super-infection exclusion protein B DUF2500 PF10694.9 EKX41758.1 - 0.019 15.5 0.4 0.033 14.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) MAP17 PF15807.5 EKX41758.1 - 0.032 14.5 0.1 0.041 14.1 0.1 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Shisa PF13908.6 EKX41758.1 - 0.032 14.5 0.2 0.044 14.0 0.2 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Miga PF10265.9 EKX41758.1 - 0.065 12.2 1.6 0.083 11.9 1.6 1.1 1 0 0 1 1 1 0 Mitoguardin DUF3671 PF12420.8 EKX41758.1 - 0.071 13.2 0.1 0.098 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function YajC PF02699.15 EKX41758.1 - 0.09 12.7 1.3 0.16 11.9 1.3 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit DUF2457 PF10446.9 EKX41758.1 - 1.7 7.7 9.4 2.1 7.4 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Phycoerythr_ab PF02972.14 EKX41761.1 - 2.7e-30 103.9 1.1 3.2e-30 103.7 0.3 1.6 2 0 0 2 2 2 1 Phycoerythrin, alpha/beta chain TAT_signal PF10518.9 EKX41761.1 - 0.0032 17.2 0.5 0.0032 17.2 0.5 2.0 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence KAAG1 PF15354.6 EKX41761.1 - 0.016 15.7 0.2 0.026 15.1 0.2 1.4 1 0 0 1 1 1 0 Kidney-associated antigen 1 Alpha_kinase PF02816.18 EKX41762.1 - 4.2e-48 163.9 0.2 5.1e-48 163.6 0.2 1.1 1 0 0 1 1 1 1 Alpha-kinase family ATF7IP_BD PF16788.5 EKX41764.1 - 1.6 8.8 11.9 0.048 13.8 2.0 2.2 2 0 0 2 2 2 0 ATF-interacting protein binding domain HP0268 PF18618.1 EKX41765.1 - 0.017 15.6 0.2 0.025 15.0 0.2 1.3 1 0 0 1 1 1 0 HP0268 WW PF00397.26 EKX41766.1 - 4.4e-11 42.7 2.2 6.4e-11 42.1 2.2 1.3 1 0 0 1 1 1 1 WW domain zf-C3HC4_3 PF13920.6 EKX41768.1 - 2.8e-08 33.5 13.0 2.8e-08 33.5 13.0 3.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) FG-GAP_2 PF14312.6 EKX41768.1 - 0.00059 20.0 0.9 3.3 8.0 0.0 3.9 4 0 0 4 4 4 2 FG-GAP repeat DARPP-32 PF05395.12 EKX41768.1 - 9.3 6.5 15.8 22 5.2 15.8 1.6 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Pkinase PF00069.25 EKX41770.1 - 2.7e-74 249.9 0.1 3.9e-74 249.3 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX41770.1 - 1.4e-41 142.5 0.0 2.2e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EKX41770.1 - 5.7e-31 106.5 0.8 2.2e-17 63.0 0.3 3.0 3 0 0 3 3 3 2 POLO box duplicated region Kinase-like PF14531.6 EKX41770.1 - 1.2e-10 41.3 0.0 8.9e-07 28.5 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.14 EKX41770.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EKX41770.1 - 0.011 15.3 1.7 0.027 14.1 1.7 1.6 1 1 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 EKX41770.1 - 0.017 14.1 0.5 0.027 13.4 0.5 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF4724 PF15852.5 EKX41770.1 - 0.92 10.0 3.5 1.3 9.6 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4724) FKBP_C PF00254.28 EKX41771.1 - 6.7e-34 116.1 0.2 1.6e-33 114.9 0.0 1.6 1 1 1 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TMEM164 PF14808.6 EKX41772.1 - 2.2e-08 33.8 7.0 2.2e-08 33.8 7.0 1.8 1 1 1 2 2 2 1 TMEM164 family LEAP-2 PF07359.11 EKX41772.1 - 0.12 12.2 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Cyclin_N PF00134.23 EKX41777.1 - 9.6e-09 35.1 0.2 1.7e-08 34.2 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain AAA_5 PF07728.14 EKX41778.1 - 1.3e-68 229.3 0.0 4.8e-34 117.3 0.0 4.2 3 1 0 3 3 3 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EKX41778.1 - 3.3e-06 27.6 0.6 1.1 9.6 0.0 4.8 4 1 0 5 5 5 2 AAA ATPase domain AAA_7 PF12775.7 EKX41778.1 - 0.0035 16.9 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_22 PF13401.6 EKX41778.1 - 0.017 15.4 0.4 5 7.4 0.0 4.4 5 0 0 5 5 5 0 AAA domain CbbQ_C PF08406.10 EKX41778.1 - 0.019 15.2 0.0 0.064 13.5 0.0 2.0 1 0 0 1 1 1 0 CbbQ/NirQ/NorQ C-terminal VWA_2 PF13519.6 EKX41778.1 - 0.02 15.5 0.0 0.1 13.3 0.0 2.3 2 0 0 2 2 2 0 von Willebrand factor type A domain CBM_20 PF00686.19 EKX41779.1 - 8.4e-32 109.0 0.2 1.6e-17 63.1 0.0 2.5 2 0 0 2 2 2 2 Starch binding domain CENP-F_leu_zip PF10473.9 EKX41779.1 - 0.0011 19.0 7.6 0.0011 19.0 7.6 9.5 2 2 5 8 8 8 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mce4_CUP1 PF11887.8 EKX41779.1 - 0.048 13.1 1.1 0.16 11.4 1.1 1.9 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative Cwf_Cwc_15 PF04889.12 EKX41780.1 - 4.7 6.9 39.4 6 6.5 17.4 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF5595 PF18077.1 EKX41781.1 - 0.16 12.1 0.2 0.16 12.1 0.2 3.9 4 2 2 6 6 6 0 Domain of unknown function (DUF5595) DUF4131 PF13567.6 EKX41781.1 - 0.59 9.8 8.7 1.2 8.7 8.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Hydrolase_4 PF12146.8 EKX41783.1 - 7.3e-65 218.6 0.1 8.5e-65 218.4 0.1 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EKX41783.1 - 6.5e-09 36.7 1.2 8.6e-09 36.3 1.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EKX41783.1 - 8.5e-08 32.1 0.1 2.1e-06 27.6 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 EKX41783.1 - 0.00018 21.3 0.0 0.12 12.2 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family PGAP1 PF07819.13 EKX41783.1 - 0.00042 20.1 0.0 0.0006 19.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Peptidase_S9 PF00326.21 EKX41783.1 - 0.00099 18.6 0.0 0.018 14.5 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 EKX41783.1 - 0.0053 16.4 0.0 0.0073 16.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 EKX41783.1 - 0.01 14.8 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S15 PF02129.18 EKX41783.1 - 0.018 14.6 0.0 0.076 12.6 0.0 1.9 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 EKX41783.1 - 0.04 13.7 0.0 2.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase FSH1 PF03959.13 EKX41783.1 - 0.1 12.2 0.0 0.25 11.0 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase (FSH1) U-box PF04564.15 EKX41784.1 - 6.7e-10 39.0 0.1 1.1e-09 38.3 0.1 1.3 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX41784.1 - 0.0004 20.2 0.1 0.00065 19.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 EKX41784.1 - 0.0011 19.0 0.1 0.0032 17.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 EKX41784.1 - 0.0038 17.2 0.9 0.0052 16.8 0.0 1.7 2 0 0 2 2 2 1 RING-type zinc-finger Cyt-b5 PF00173.28 EKX41785.1 - 1e-06 28.8 0.1 1.3e-05 25.3 0.1 2.5 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2158 PF09926.9 EKX41785.1 - 0.016 14.9 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) Fe-S_assembly PF04384.13 EKX41785.1 - 0.058 14.0 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 Iron-sulphur cluster assembly PigN PF04987.14 EKX41788.1 - 8.4e-43 146.9 9.3 8.4e-43 146.9 9.3 2.1 1 1 1 2 2 2 2 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 EKX41788.1 - 3.2e-06 27.0 0.2 9.5e-06 25.4 0.1 1.7 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EKX41788.1 - 2.6e-05 23.8 0.0 4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Lact_bio_phlase PF09508.10 EKX41788.1 - 0.14 10.5 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase N-terminal TIM barrel domain EF-hand_7 PF13499.6 EKX41789.1 - 0.00084 19.7 0.6 0.0047 17.3 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 EKX41789.1 - 0.01 15.6 2.5 0.16 11.9 0.1 3.1 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_6 PF13405.6 EKX41789.1 - 0.069 13.1 2.6 0.28 11.2 0.1 3.2 3 0 0 3 3 3 0 EF-hand domain UPF0560 PF10577.9 EKX41789.1 - 0.26 9.8 0.6 0.3 9.5 0.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Mito_carr PF00153.27 EKX41790.1 - 1.4e-45 153.1 8.9 2e-18 66.1 0.4 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Got1 PF04178.12 EKX41792.1 - 2.5e-34 118.1 14.8 3.8e-34 117.5 14.8 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family PDR_CDR PF06422.12 EKX41792.1 - 0.17 11.8 0.9 0.28 11.1 0.0 1.8 2 0 0 2 2 2 0 CDR ABC transporter PspB PF06667.12 EKX41792.1 - 0.76 9.9 2.5 24 5.1 1.0 2.7 3 0 0 3 3 3 0 Phage shock protein B DUF2207 PF09972.9 EKX41792.1 - 4.3 6.0 10.2 18 3.9 10.2 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) V-SNARE_C PF12352.8 EKX41793.1 - 1.5e-18 66.8 6.1 1.2e-17 64.0 6.9 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 EKX41793.1 - 2e-07 31.3 0.5 2e-07 31.3 0.5 2.8 3 1 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 EKX41793.1 - 0.00021 21.1 0.9 0.00021 21.1 0.9 2.1 2 0 0 2 2 2 1 Sec20 DUF883 PF05957.13 EKX41793.1 - 0.088 13.4 5.6 0.48 11.1 0.3 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) FUSC PF04632.12 EKX41793.1 - 0.12 10.9 0.5 0.25 9.8 0.3 1.5 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF745 PF05335.13 EKX41793.1 - 0.29 10.8 8.4 2 8.1 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Bcl-2 PF00452.19 EKX41793.1 - 0.3 11.8 2.1 0.76 10.5 0.3 2.5 2 2 0 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family Sec34 PF04136.15 EKX41793.1 - 0.66 9.9 4.7 0.38 10.6 0.3 2.4 2 1 1 3 3 3 0 Sec34-like family CENP-H PF05837.12 EKX41793.1 - 1.8 9.0 8.5 0.32 11.4 1.9 2.4 2 1 0 2 2 2 0 Centromere protein H (CENP-H) MPS2 PF17060.5 EKX41793.1 - 2.2 7.5 7.8 1.2 8.3 0.7 2.1 1 1 0 2 2 2 0 Monopolar spindle protein 2 DUF2721 PF11026.8 EKX41793.1 - 9.6 6.1 6.5 9.7 6.1 3.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) DUF3021 PF11457.8 EKX41795.1 - 0.063 13.6 0.0 0.069 13.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) DRIM PF07539.12 EKX41795.1 - 0.15 10.3 0.0 0.17 10.1 0.0 1.1 1 0 0 1 1 1 0 Down-regulated in metastasis FLYWCH_u PF16662.5 EKX41797.1 - 0.0047 16.9 0.2 0.0082 16.2 0.2 1.4 1 0 0 1 1 1 1 FLYWCH-type zinc finger-containing protein 1 DSPn PF14671.6 EKX41798.1 - 6.5e-16 59.0 0.0 1e-15 58.4 0.0 1.3 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EKX41798.1 - 2.7e-08 33.7 0.0 4e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX41798.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase KH_2 PF07650.17 EKX41798.1 - 0.2 11.5 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 KH domain BLUF PF04940.12 EKX41799.1 - 0.016 15.3 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 Sensors of blue-light using FAD DSPn PF14671.6 EKX41800.1 - 2e-16 60.7 0.0 2.6e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half RWP-RK PF02042.15 EKX41800.1 - 0.0034 17.3 0.0 0.0066 16.4 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain Sigma70_r4_2 PF08281.12 EKX41800.1 - 0.0037 16.9 1.1 0.086 12.5 0.0 3.0 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_31 PF13560.6 EKX41800.1 - 4.5 7.7 6.8 4.2 7.8 0.8 3.0 2 1 0 2 2 2 0 Helix-turn-helix domain FLYWCH_u PF16662.5 EKX41801.1 - 0.0047 16.9 0.2 0.0082 16.2 0.2 1.4 1 0 0 1 1 1 1 FLYWCH-type zinc finger-containing protein 1 PDZ_6 PF17820.1 EKX41802.1 - 7.4e-12 44.9 0.9 1.3e-11 44.2 0.9 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX41802.1 - 2.3e-09 37.4 0.0 4.5e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX41802.1 - 1.2e-07 32.0 0.0 2.3e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX41802.1 - 0.00068 19.6 0.1 0.0013 18.7 0.1 1.4 1 0 0 1 1 1 1 Tricorn protease PDZ domain LSM PF01423.22 EKX41803.1 - 1.3e-15 56.8 0.1 1.8e-15 56.3 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EKX41803.1 - 0.00026 21.1 0.0 0.00034 20.7 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Ski2_N PF17911.1 EKX41803.1 - 0.02 14.7 0.0 0.021 14.6 0.0 1.1 1 0 0 1 1 1 0 Ski2 N-terminal region DUF4937 PF16291.5 EKX41804.1 - 0.0094 16.2 3.6 0.074 13.3 0.3 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF4937 Mvb12 PF09452.10 EKX41804.1 - 0.06 13.8 0.6 0.23 11.9 0.6 2.0 1 0 0 1 1 1 0 ESCRT-I subunit Mvb12 DnaJ PF00226.31 EKX41806.1 - 8.9e-28 96.2 4.5 1.1e-27 95.9 4.5 1.1 1 0 0 1 1 1 1 DnaJ domain LTXXQ PF07813.12 EKX41806.1 - 0.026 15.2 0.6 0.039 14.7 0.3 1.6 2 0 0 2 2 2 0 LTXXQ motif family protein DUF884 PF05959.11 EKX41806.1 - 0.082 12.5 0.0 0.095 12.3 0.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF884) BTB_2 PF02214.22 EKX41808.1 - 1.9e-12 47.4 0.1 3.3e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain IBN_N PF03810.19 EKX41809.1 - 6.4e-10 38.8 1.9 7.7e-08 32.1 0.3 3.3 2 0 0 2 2 2 2 Importin-beta N-terminal domain HEAT_EZ PF13513.6 EKX41809.1 - 2.6e-06 27.8 7.5 2 9.0 0.0 7.9 8 1 0 8 8 8 2 HEAT-like repeat HEAT PF02985.22 EKX41809.1 - 4e-05 23.5 9.0 0.018 15.3 0.1 7.3 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.6 EKX41809.1 - 0.0002 21.7 12.1 0.32 11.4 0.5 6.4 5 1 2 7 7 7 3 HEAT repeats FAM25 PF15825.5 EKX41809.1 - 0.093 13.1 0.6 0.73 10.2 0.0 2.7 2 0 0 2 2 2 0 FAM25 family zf-C3HC4_2 PF13923.6 EKX41810.1 - 3e-06 27.0 1.9 3e-06 27.0 1.9 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EKX41810.1 - 5.3e-06 26.2 0.9 5.3e-06 26.2 0.9 3.6 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX41810.1 - 4.3e-05 23.5 2.7 4.3e-05 23.5 2.7 2.8 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 EKX41810.1 - 0.00012 22.4 2.0 0.00012 22.4 2.0 3.7 4 1 0 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 EKX41810.1 - 0.00023 21.0 1.3 0.00023 21.0 1.3 3.5 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX41810.1 - 0.00032 20.6 2.5 0.00032 20.6 2.5 3.8 2 2 2 4 4 4 1 zinc-RING finger domain Zn_Tnp_IS91 PF14319.6 EKX41810.1 - 0.0072 16.3 16.4 0.18 11.9 2.0 3.3 2 1 1 3 3 3 2 Transposase zinc-binding domain zf-RING_4 PF14570.6 EKX41810.1 - 0.018 14.8 2.1 0.018 14.8 2.1 3.9 4 1 0 4 4 4 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EKX41810.1 - 0.043 13.7 5.2 0.043 13.7 5.2 3.9 3 2 1 4 4 4 0 Prokaryotic RING finger family 4 Bestrophin PF01062.21 EKX41811.1 - 1.3e-15 57.6 0.0 1.5e-15 57.3 0.0 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF4051 PF13260.6 EKX41817.1 - 5.3 6.9 5.2 0.95 9.2 0.7 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4051) Epimerase PF01370.21 EKX41819.1 - 1.8e-07 30.9 0.0 2.6e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EKX41819.1 - 0.12 12.3 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding CcdA PF07362.12 EKX41821.1 - 0.069 13.6 4.2 2.3 8.7 0.1 3.5 2 2 2 4 4 4 0 Post-segregation antitoxin CcdA DUF1128 PF06569.11 EKX41821.1 - 0.14 12.2 1.8 13 5.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1128) DUF2624 PF11116.8 EKX41821.1 - 1.9 9.5 7.0 5.2 8.0 0.2 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2624) PDZ PF00595.24 EKX41823.1 - 6.6e-17 61.6 0.0 3e-07 30.7 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX41823.1 - 3.3e-15 56.2 0.0 2.6e-06 27.7 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EKX41823.1 - 3.3e-15 55.7 1.2 2.1e-06 27.5 0.0 3.0 2 1 0 2 2 2 2 PDZ domain SR-25 PF10500.9 EKX41823.1 - 0.00013 21.7 27.6 0.00013 21.7 27.6 5.0 2 2 4 6 6 5 1 Nuclear RNA-splicing-associated protein NPV_P10 PF05531.12 EKX41823.1 - 5.4 7.5 8.0 2.7 8.5 0.8 3.6 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Secretin_N_2 PF07655.13 EKX41823.1 - 5.9 7.5 26.2 0.42 11.2 20.1 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain Ecl1 PF12855.7 EKX41823.1 - 6.4 7.9 25.1 0.074 14.2 8.3 3.3 3 1 0 3 3 3 0 ECL1/2/3 zinc binding proteins DUF3499 PF12005.8 EKX41824.1 - 0.096 13.3 0.0 0.17 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3499) Glyco_transf_8 PF01501.20 EKX41825.1 - 1.4e-27 96.9 0.8 1.8e-27 96.5 0.1 1.4 2 0 0 2 2 2 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 EKX41825.1 - 5e-06 26.6 0.5 9e-06 25.8 0.5 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.8 EKX41825.1 - 0.00074 18.9 0.2 0.016 14.6 0.0 2.8 2 1 0 2 2 2 1 Mannosyltransferase putative IRF-2BP1_2 PF11261.8 EKX41826.1 - 0.093 12.3 0.2 0.15 11.6 0.2 1.3 1 0 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger Methyltransf_11 PF08241.12 EKX41827.1 - 0.0002 21.9 0.0 0.00058 20.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX41827.1 - 0.003 18.3 0.0 0.012 16.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX41827.1 - 0.012 15.5 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF2151 PF10221.9 EKX41827.1 - 0.024 13.2 3.6 0.029 13.0 3.6 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator DUF4834 PF16118.5 EKX41827.1 - 0.043 14.8 1.1 0.075 14.0 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Methyltransf_25 PF13649.6 EKX41827.1 - 0.07 13.8 0.0 0.2 12.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Sec62 PF03839.16 EKX41827.1 - 0.075 12.5 4.6 0.11 11.9 4.6 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 NPR3 PF03666.13 EKX41827.1 - 0.44 9.3 7.7 0.59 8.9 7.7 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Zip PF02535.22 EKX41827.1 - 0.54 9.4 2.0 0.59 9.3 2.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Aquarius_N PF16399.5 EKX41827.1 - 0.78 7.7 4.4 1.1 7.2 4.4 1.1 1 0 0 1 1 1 0 Intron-binding protein aquarius N-terminus Presenilin PF01080.17 EKX41827.1 - 3.7 6.2 9.5 5.9 5.6 9.5 1.2 1 0 0 1 1 1 0 Presenilin Atrophin-1 PF03154.15 EKX41827.1 - 6.8 4.8 10.9 8.6 4.5 10.9 1.0 1 0 0 1 1 1 0 Atrophin-1 family TPR_17 PF13431.6 EKX41828.1 - 1.7e-29 100.0 11.4 0.001 19.3 0.1 7.3 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_14 PF13428.6 EKX41828.1 - 1.2e-20 72.4 4.9 0.12 13.3 0.3 7.8 2 2 6 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 EKX41828.1 - 1.8e-19 68.6 6.9 0.032 14.0 0.0 7.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 EKX41828.1 - 2.6e-18 64.6 8.7 0.22 11.7 0.0 8.2 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 EKX41828.1 - 6.8e-17 61.8 8.9 1.7e-06 28.5 0.4 4.8 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 EKX41828.1 - 2e-16 58.8 1.4 0.88 9.9 0.1 7.9 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EKX41828.1 - 4.2e-16 59.2 9.2 0.0091 16.5 0.7 6.2 3 2 3 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 EKX41828.1 - 4.5e-12 46.1 21.1 0.00011 22.5 0.3 5.7 2 2 5 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 EKX41828.1 - 8.9e-12 44.2 11.6 0.54 10.4 0.1 7.2 8 0 0 8 8 7 4 Tetratricopeptide repeat Sel1 PF08238.12 EKX41828.1 - 1.8e-08 34.8 2.7 2 9.2 0.0 6.4 6 0 0 6 6 6 2 Sel1 repeat Coatomer_E PF04733.14 EKX41828.1 - 8.5e-08 32.0 6.7 0.16 11.4 0.1 5.5 2 2 2 6 6 6 2 Coatomer epsilon subunit TPR_11 PF13414.6 EKX41828.1 - 1.1e-07 31.4 6.8 0.21 11.3 0.1 6.4 7 0 0 7 7 7 2 TPR repeat TPR_6 PF13174.6 EKX41828.1 - 2.4e-07 31.0 1.6 0.17 12.6 0.2 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX41828.1 - 2.9e-05 23.8 15.6 2.6 8.1 0.1 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPPII_N PF12583.8 EKX41828.1 - 0.00072 20.1 2.9 4.5 7.8 0.0 4.9 4 1 1 5 5 5 1 Tripeptidyl peptidase II N terminal B12-binding_2 PF02607.17 EKX41828.1 - 0.0014 19.0 0.0 0.16 12.4 0.0 3.2 3 0 0 3 3 3 1 B12 binding domain DUF4689 PF15755.5 EKX41828.1 - 0.0046 16.6 0.3 19 4.8 0.0 4.4 4 1 1 5 5 5 0 Domain of unknown function (DUF4689) Fis1_TPR_C PF14853.6 EKX41828.1 - 0.0098 15.9 0.1 18 5.5 0.0 3.7 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat AATase PF07247.12 EKX41828.1 - 0.022 13.3 0.0 0.035 12.7 0.0 1.2 1 0 0 1 1 1 0 Alcohol acetyltransferase DUF4192 PF13830.6 EKX41828.1 - 0.12 12.5 1.8 0.61 10.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) DUF3067 PF11267.8 EKX41830.1 - 8.9e-13 48.7 0.0 1.2e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3067) Beta_helix PF13229.6 EKX41832.1 - 0.02 14.7 0.4 0.034 14.0 0.4 1.3 1 0 0 1 1 1 0 Right handed beta helix region zf-RING_2 PF13639.6 EKX41833.1 - 8.8e-12 45.2 13.3 1.3e-11 44.6 13.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX41833.1 - 2.8e-07 30.3 13.2 4.4e-07 29.6 13.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EKX41833.1 - 8.1e-07 28.7 7.3 8.1e-07 28.7 7.3 1.7 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EKX41833.1 - 1.3e-05 25.1 6.0 1.3e-05 25.1 6.0 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EKX41833.1 - 1.5e-05 24.7 10.8 2.3e-05 24.2 10.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX41833.1 - 1.6e-05 25.1 13.0 3e-05 24.2 12.3 1.8 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EKX41833.1 - 3.2e-05 23.8 10.5 5e-05 23.2 10.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EKX41833.1 - 0.0015 18.6 3.2 0.0026 17.8 3.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EKX41833.1 - 0.0021 17.9 11.3 0.0041 16.9 11.3 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 EKX41833.1 - 0.0081 16.4 10.5 0.015 15.6 10.5 1.4 1 0 0 1 1 1 1 RING-like domain Zn_ribbon_17 PF17120.5 EKX41833.1 - 0.0082 15.7 8.3 0.015 14.9 8.3 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EKX41833.1 - 0.0095 15.8 11.8 0.015 15.2 8.7 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 FANCL_C PF11793.8 EKX41833.1 - 0.65 10.2 10.7 1.9 8.7 9.7 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain DNA_ligase_ZBD PF03119.16 EKX41833.1 - 1.6 8.8 7.3 0.9 9.6 0.1 2.6 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain RINGv PF12906.7 EKX41833.1 - 2.9 8.1 11.2 5.1 7.3 11.2 1.4 1 0 0 1 1 1 0 RING-variant domain zf-Nse PF11789.8 EKX41833.1 - 3.4 7.5 7.6 8.2 6.3 7.6 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Pga1 PF10333.9 EKX41834.1 - 0.0007 19.5 0.0 0.0037 17.1 0.0 2.0 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator Thioredoxin PF00085.20 EKX41836.1 - 1e-31 109.0 0.0 1.3e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EKX41836.1 - 5.7e-11 42.8 0.0 8e-10 39.1 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EKX41836.1 - 1.4e-08 34.9 0.0 4.4e-07 30.1 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 EKX41836.1 - 5.9e-07 29.3 0.0 8.4e-07 28.8 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.24 EKX41836.1 - 0.00068 19.8 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin TraF PF13728.6 EKX41836.1 - 0.00086 19.2 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.10 EKX41836.1 - 0.001 18.8 0.1 0.01 15.6 0.1 1.9 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.6 EKX41836.1 - 0.0013 18.8 0.0 0.0025 18.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 EKX41836.1 - 0.0019 18.2 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.21 EKX41836.1 - 0.002 18.1 0.0 0.0049 16.8 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 EKX41836.1 - 0.0024 17.3 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HyaE PF07449.11 EKX41836.1 - 0.0026 17.7 0.0 0.0046 16.9 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.6 EKX41836.1 - 0.004 16.8 0.0 0.64 9.7 0.0 2.4 1 1 1 2 2 2 1 Thioredoxin DUF836 PF05768.14 EKX41836.1 - 0.022 15.2 0.0 0.032 14.7 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.6 EKX41836.1 - 0.064 13.4 0.0 8.3 6.5 0.0 2.3 1 1 1 2 2 2 0 Thioredoxin DSBA PF01323.20 EKX41836.1 - 0.15 11.8 0.0 9 6.0 0.0 2.4 2 1 1 3 3 3 0 DSBA-like thioredoxin domain Phycoerythr_ab PF02972.14 EKX41837.1 - 2.3e-26 91.3 0.1 3.1e-26 91.0 0.1 1.2 1 0 0 1 1 1 1 Phycoerythrin, alpha/beta chain ubiquitin PF00240.23 EKX41838.1 - 2.5e-22 78.4 0.1 3.4e-22 78.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EKX41838.1 - 1.7e-09 37.4 0.1 2.1e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EKX41838.1 - 0.046 14.2 0.0 0.19 12.2 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EKX41838.1 - 0.065 13.6 0.0 0.093 13.1 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EKX41838.1 - 0.085 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Baculo_PEP_C PF04513.12 EKX41839.1 - 0.0047 17.0 0.6 0.1 12.6 0.0 3.0 3 1 1 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 EKX41839.1 - 0.0088 16.1 6.6 0.021 14.8 0.5 3.4 2 1 1 3 3 3 1 Protein of unknown function (DUF1664) Nup54 PF13874.6 EKX41839.1 - 0.02 15.0 15.6 0.18 11.9 0.4 3.7 3 0 0 3 3 3 0 Nucleoporin complex subunit 54 Laminin_II PF06009.12 EKX41839.1 - 0.082 12.9 8.2 3.1 7.8 0.1 3.8 2 1 1 3 3 3 0 Laminin Domain II LXG PF04740.12 EKX41839.1 - 0.64 9.7 6.4 1.1 9.0 0.4 3.6 3 1 1 4 4 4 0 LXG domain of WXG superfamily Prefoldin_2 PF01920.20 EKX41839.1 - 0.73 9.8 13.7 5.7 6.9 0.1 4.8 4 1 0 5 5 5 0 Prefoldin subunit DUF2721 PF11026.8 EKX41839.1 - 0.97 9.3 6.9 1.8 8.4 2.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF5082 PF16888.5 EKX41839.1 - 1.3 9.4 11.3 1.2 9.4 0.5 4.0 2 1 2 4 4 4 0 Domain of unknown function (DUF5082) HALZ PF02183.18 EKX41839.1 - 5.7 7.2 12.2 6.6 7.1 1.3 4.4 5 0 0 5 5 5 0 Homeobox associated leucine zipper GspL_C PF12693.7 EKX41840.1 - 0.014 15.2 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 GspL periplasmic domain Aldose_epim PF01263.20 EKX41842.1 - 5.2e-73 246.0 0.0 5.8e-73 245.8 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Ins145_P3_rec PF08709.11 EKX41843.1 - 2.1e-08 33.6 0.0 5e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor LMF1 PF06762.14 EKX41843.1 - 0.032 13.4 11.4 0.065 12.3 11.4 1.4 1 0 0 1 1 1 0 Lipase maturation factor DUF898 PF05987.13 EKX41843.1 - 4.3 6.3 26.4 7.9 5.4 26.4 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) TraG_N PF07916.11 EKX41843.1 - 6.2 5.6 31.7 10 4.8 31.7 1.2 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Pex24p PF06398.11 EKX41843.1 - 6.8 5.6 13.2 19 4.1 13.2 1.7 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Yip1 PF04893.17 EKX41843.1 - 7.3 6.3 13.9 14 5.4 13.9 1.3 1 0 0 1 1 1 0 Yip1 domain HTH_Tnp_Tc5 PF03221.16 EKX41844.1 - 0.00024 21.1 0.0 0.00038 20.4 0.0 1.3 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 EKX41844.1 - 0.0023 17.5 0.1 0.0051 16.4 0.1 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain Phycoerythr_ab PF02972.14 EKX41846.1 - 9.8e-33 111.8 0.1 1.7e-32 111.0 0.1 1.4 1 0 0 1 1 1 1 Phycoerythrin, alpha/beta chain TAT_signal PF10518.9 EKX41846.1 - 5.1 7.1 12.6 0.32 10.9 0.5 2.6 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence PhoD PF09423.10 EKX41847.1 - 1.8e-21 76.6 0.5 5.6e-19 68.4 0.5 3.5 1 1 0 1 1 1 1 PhoD-like phosphatase AKAP28 PF14469.6 EKX41847.1 - 0.18 11.6 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 28 kDa A-kinase anchor Guanylate_cyc PF00211.20 EKX41848.1 - 3.7e-21 75.6 0.0 4.5e-21 75.3 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain FeThRed_A PF02941.15 EKX41849.1 - 3.4e-10 39.9 0.5 5e-10 39.4 0.5 1.3 1 0 0 1 1 1 1 Ferredoxin thioredoxin reductase variable alpha chain NifZ PF04319.13 EKX41849.1 - 0.015 15.1 0.1 0.025 14.3 0.1 1.4 1 0 0 1 1 1 0 NifZ domain ABC1 PF03109.16 EKX41850.1 - 5e-39 133.1 0.2 1.1e-38 132.1 0.2 1.6 1 0 0 1 1 1 1 ABC1 family BT1 PF03092.16 EKX41851.1 - 6.6e-110 367.8 18.7 7.2e-72 242.3 11.4 2.0 1 1 1 2 2 2 2 BT1 family PUCC PF03209.15 EKX41851.1 - 0.00023 20.3 0.8 0.00023 20.3 0.8 3.8 2 1 1 3 3 3 1 PUCC protein PCP_red PF08369.10 EKX41852.1 - 4.4e-15 55.6 1.0 7.7e-15 54.8 1.0 1.4 1 0 0 1 1 1 1 Proto-chlorophyllide reductase 57 kD subunit ABC1 PF03109.16 EKX41853.1 - 2.1e-27 95.6 0.0 3.9e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EKX41853.1 - 2.6e-07 30.8 0.3 9.4e-07 29.0 0.3 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EKX41853.1 - 0.00043 19.7 0.0 0.0029 17.0 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Methyltransf_32 PF13679.6 EKX41854.1 - 7.1e-05 22.9 0.1 0.00057 19.9 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EKX41854.1 - 8.6e-05 22.2 0.0 0.00013 21.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EKX41854.1 - 0.00014 22.5 0.0 0.00037 21.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 EKX41854.1 - 0.0034 16.7 0.0 0.011 15.1 0.0 1.8 2 0 0 2 2 2 1 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.6 EKX41854.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EKX41854.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Glyco_transf_11 PF01531.16 EKX41855.1 - 0.00068 18.9 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 11 Sulfotransfer_1 PF00685.27 EKX41857.1 - 5.6e-10 39.1 0.1 2e-09 37.3 0.1 1.9 1 1 0 1 1 1 1 Sulfotransferase domain AAA_11 PF13086.6 EKX41857.1 - 0.00074 19.4 0.6 0.0027 17.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain Sulfotransfer_3 PF13469.6 EKX41857.1 - 0.0017 18.8 0.1 0.0085 16.5 0.0 2.1 2 0 0 2 2 2 1 Sulfotransferase family AAA PF00004.29 EKX41857.1 - 0.028 14.9 0.0 0.059 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EKX41857.1 - 0.035 13.6 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 EKX41857.1 - 0.08 12.5 0.0 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain Chloroa_b-bind PF00504.21 EKX41858.1 - 5.9e-42 143.9 0.1 8.4e-42 143.4 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DUF3357 PF11837.8 EKX41859.1 - 0.015 15.7 0.2 0.025 15.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) ATP-synt_D PF01813.17 EKX41859.1 - 0.14 11.9 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 ATP synthase subunit D PDEase_I PF00233.19 EKX41861.1 - 8.3e-68 228.6 3.5 8.3e-68 228.6 3.5 1.6 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase COX14 PF14880.6 EKX41862.1 - 0.56 10.1 1.7 6 6.8 1.1 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Endonuc-dimeris PF09124.10 EKX41864.1 - 0.068 13.3 0.4 0.35 11.1 0.4 2.3 2 0 0 2 2 2 0 T4 recombination endonuclease VII, dimerisation HAD_2 PF13419.6 EKX41864.1 - 6.6 6.8 9.5 0.54 10.3 1.9 2.7 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase EF-hand_6 PF13405.6 EKX41865.1 - 1.8e-05 24.3 0.1 0.0015 18.3 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 EKX41865.1 - 0.00018 20.8 1.0 0.0012 18.3 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EKX41865.1 - 0.011 16.2 0.5 0.011 16.2 0.5 3.8 5 0 0 5 5 3 0 EF-hand domain pair FPP PF05911.11 EKX41865.1 - 0.049 11.8 23.6 0.086 11.0 23.6 1.3 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Exonuc_VII_L PF02601.15 EKX41865.1 - 0.11 12.0 12.8 0.26 10.8 12.8 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit TPR_MLP1_2 PF07926.12 EKX41865.1 - 0.21 11.6 30.9 0.015 15.3 22.8 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein BicD PF09730.9 EKX41865.1 - 0.71 8.2 26.1 1.1 7.6 26.1 1.2 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D DUF4407 PF14362.6 EKX41865.1 - 1 8.6 14.8 1.7 7.9 14.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GAS PF13851.6 EKX41865.1 - 1.9 7.8 28.7 0.25 10.7 10.1 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Tn7_Tnp_TnsA_C PF08721.11 EKX41865.1 - 2.1 9.1 7.7 12 6.6 0.3 3.6 1 1 0 2 2 2 0 TnsA endonuclease C terminal DUF3584 PF12128.8 EKX41865.1 - 2.8 5.3 23.0 4.2 4.8 23.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.6 EKX41865.1 - 3.3 6.2 15.7 5.2 5.6 15.7 1.2 1 0 0 1 1 1 0 AAA domain DUF2564 PF10819.8 EKX41865.1 - 4.5 7.7 8.9 0.44 11.0 2.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) Fez1 PF06818.15 EKX41865.1 - 4.7 7.6 25.6 2.1 8.8 22.6 2.0 2 0 0 2 2 1 0 Fez1 V_ATPase_I PF01496.19 EKX41865.1 - 6.8 4.5 13.2 11 3.7 13.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lebercilin PF15619.6 EKX41865.1 - 7.4 6.2 31.9 0.72 9.5 23.2 2.8 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease HAUS-augmin3 PF14932.6 EKX41865.1 - 8.5 5.9 33.6 0.21 11.2 17.9 2.8 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 Asp PF00026.23 EKX41866.1 - 2.3e-13 50.3 0.0 2.7e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EKX41866.1 - 0.0038 17.5 0.0 0.067 13.4 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal SP2 PF03014.14 EKX41866.1 - 0.018 13.5 0.0 0.026 13.0 0.0 1.1 1 0 0 1 1 1 0 Structural protein 2 Ig_C19orf38 PF17737.1 EKX41867.1 - 0.1 12.9 0.5 2.7 8.4 0.3 2.2 2 0 0 2 2 2 0 Ig domain in C19orf38 (HIDE1) DUF2103 PF09876.9 EKX41868.1 - 3.5e-16 59.0 0.0 3.6e-16 58.9 0.0 1.0 1 0 0 1 1 1 1 Predicted metal-binding protein (DUF2103) Gaa1 PF04114.14 EKX41869.1 - 2.2e-59 201.8 0.0 2e-58 198.7 0.0 2.3 2 1 0 2 2 2 1 Gaa1-like, GPI transamidase component TrkA_TMD PF18613.1 EKX41869.1 - 0.022 14.2 1.0 0.072 12.5 1.0 1.9 1 0 0 1 1 1 0 Tyrosine kinase receptor A trans-membrane domain MMTV_SAg PF01054.17 EKX41870.1 - 6.2 6.3 9.5 0.29 10.6 2.1 2.4 2 1 0 2 2 2 0 Mouse mammary tumour virus superantigen AAA_14 PF13173.6 EKX41871.1 - 0.00038 20.5 0.0 0.0015 18.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EKX41871.1 - 0.019 14.8 0.0 0.019 14.8 0.0 3.8 2 1 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 EKX41871.1 - 0.021 15.2 0.0 0.063 13.7 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 EKX41871.1 - 0.027 14.0 0.0 0.072 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EKX41871.1 - 0.06 13.6 0.0 0.06 13.6 0.0 3.0 2 1 0 2 2 1 0 AAA domain AAA_19 PF13245.6 EKX41871.1 - 0.074 13.4 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EKX41871.1 - 0.11 11.9 0.0 0.28 10.5 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF150_C PF17384.2 EKX41871.1 - 0.24 11.6 12.2 5 7.3 0.2 4.2 2 1 0 3 3 3 0 RimP C-terminal SH3 domain AAA_16 PF13191.6 EKX41871.1 - 0.41 11.0 0.0 0.41 11.0 0.0 2.8 2 1 0 2 2 1 0 AAA ATPase domain SapB_1 PF05184.15 EKX41871.1 - 0.78 9.8 5.5 74 3.5 0.1 3.8 4 0 0 4 4 4 0 Saposin-like type B, region 1 ABC_tran PF00005.27 EKX41871.1 - 0.93 10.0 0.0 0.93 10.0 0.0 3.1 2 1 0 2 2 1 0 ABC transporter Myb_DNA-bind_3 PF12776.7 EKX41871.1 - 2.3 9.2 25.3 0.096 13.7 4.3 5.2 3 1 3 6 6 5 0 Myb/SANT-like DNA-binding domain EPTP PF03736.17 EKX41872.1 - 3.9e-22 78.0 9.1 4.5e-05 23.4 0.0 7.0 7 0 0 7 7 7 6 EPTP domain Lactonase PF10282.9 EKX41872.1 - 0.00085 18.7 0.0 0.069 12.4 0.0 2.6 2 1 0 2 2 2 2 Lactonase, 7-bladed beta-propeller Kelch_6 PF13964.6 EKX41872.1 - 0.093 13.0 0.0 0.33 11.3 0.0 2.0 2 0 0 2 2 2 0 Kelch motif DiS_P_DiS PF06750.13 EKX41873.1 - 0.28 11.3 5.3 0.6 10.3 5.3 1.7 1 1 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain RRM_1 PF00076.22 EKX41875.1 - 8.9e-05 22.2 0.1 0.00032 20.5 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1887 PF09002.11 EKX41875.1 - 0.17 10.5 0.0 0.22 10.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) CHASE5 PF17149.4 EKX41876.1 - 0.0029 17.5 0.0 1.1 9.3 0.0 2.4 2 0 0 2 2 2 2 Periplasmic sensor domain found in signal transduction proteins TPR_10 PF13374.6 EKX41877.1 - 1.2e-07 31.4 0.4 0.00013 21.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX41877.1 - 2.2e-07 31.1 5.6 0.0074 16.6 0.0 4.3 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX41877.1 - 0.00054 19.9 5.2 6.7 7.1 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat Antibiotic_NAT PF02522.14 EKX41877.1 - 0.057 13.2 0.0 0.086 12.6 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase TPR_1 PF00515.28 EKX41877.1 - 0.68 9.8 10.1 6.1 6.8 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-4CXXC_R1 PF10497.9 EKX41878.1 - 7.9 6.8 29.2 12 6.2 29.2 1.3 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 WD40 PF00400.32 EKX41879.1 - 1.9e-08 34.8 13.0 6.6e-05 23.6 0.5 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX41879.1 - 0.012 15.8 0.1 2.3 8.6 0.1 4.0 3 1 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 EKX41879.1 - 0.064 13.0 4.3 15 5.2 0.1 4.1 3 1 2 5 5 5 0 TUP1-like enhancer of split Occludin_ELL PF07303.13 EKX41880.1 - 6.6e-07 30.0 5.6 6.6e-07 30.0 5.6 2.1 2 0 0 2 2 2 1 Occludin homology domain TACC_C PF05010.14 EKX41880.1 - 0.0022 17.8 2.3 0.0022 17.8 2.3 2.4 2 0 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal eIF3_N PF09440.10 EKX41880.1 - 0.034 14.6 2.5 0.086 13.3 2.5 1.6 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain Peptidase_M27 PF01742.17 EKX41880.1 - 0.089 11.9 1.2 0.13 11.3 1.2 1.2 1 0 0 1 1 1 0 Clostridial neurotoxin zinc protease DUF3987 PF13148.6 EKX41880.1 - 1.4 7.9 9.3 4 6.3 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Pox_T4_N PF04491.12 EKX41882.1 - 0.024 14.5 0.2 0.52 10.2 0.0 2.2 2 0 0 2 2 2 0 Poxvirus T4 protein, N terminus Cu-oxidase_2 PF07731.14 EKX41883.1 - 2.7e-07 30.4 0.1 6.3e-07 29.2 0.1 1.6 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 EKX41883.1 - 2.3e-06 27.6 0.3 0.0068 16.4 0.1 2.9 3 0 0 3 3 3 2 Multicopper oxidase LapA_dom PF06305.11 EKX41884.1 - 0.0051 16.6 0.1 0.0068 16.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain DUF3185 PF11381.8 EKX41884.1 - 0.014 15.3 0.3 0.018 15.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) MORN PF02493.20 EKX41885.1 - 3.9e-25 86.2 37.2 6.9e-07 28.8 1.9 8.8 8 1 0 8 8 8 7 MORN repeat FKBP_C PF00254.28 EKX41886.1 - 3.2e-26 91.5 0.0 5.1e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TAT_signal PF10518.9 EKX41886.1 - 0.12 12.3 0.2 0.24 11.3 0.2 1.5 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence NAD_binding_6 PF08030.12 EKX41887.1 - 2.8e-14 53.5 0.0 1.6e-11 44.6 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 EKX41887.1 - 5.4e-05 23.8 0.0 0.00054 20.6 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Mg_trans_NIPA PF05653.14 EKX41890.1 - 3e-06 26.6 0.8 4.1e-06 26.1 0.8 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA Glyco_transf_36 PF06165.11 EKX41890.1 - 0.065 12.6 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 36 Pex16 PF08610.10 EKX41891.1 - 1e-27 97.2 1.0 1.1e-09 37.9 0.0 3.1 3 0 0 3 3 3 3 Peroxisomal membrane protein (Pex16) BT1 PF03092.16 EKX41892.1 - 5.9e-96 321.8 27.2 2.1e-66 224.2 11.1 2.0 2 0 0 2 2 2 2 BT1 family TIG PF01833.24 EKX41893.1 - 1e-09 38.3 0.9 1.2e-09 38.1 0.9 1.1 1 0 0 1 1 1 1 IPT/TIG domain TIG_plexin PF17960.1 EKX41893.1 - 0.064 13.3 0.0 0.068 13.2 0.0 1.2 1 0 0 1 1 1 0 TIG domain TIG PF01833.24 EKX41894.1 - 1.3e-137 448.2 117.7 8.7e-10 38.6 0.2 22.7 22 1 0 22 22 22 21 IPT/TIG domain TIG_plexin PF17960.1 EKX41894.1 - 4.1e-23 81.2 2.8 5.7 7.0 0.0 18.7 21 0 0 21 21 21 3 TIG domain Anth_Ig PF05587.13 EKX41894.1 - 1.7e-14 54.0 7.3 0.013 15.8 0.0 9.8 12 0 0 12 12 12 4 Anthrax receptor extracellular domain RHD_dimer PF16179.5 EKX41894.1 - 0.034 14.2 0.0 15 5.6 0.0 4.8 4 0 0 4 4 4 0 Rel homology dimerisation domain TIG PF01833.24 EKX41895.1 - 1.7e-185 601.7 158.5 9.9e-10 38.4 0.2 31.5 31 1 0 31 31 31 30 IPT/TIG domain TIG_plexin PF17960.1 EKX41895.1 - 1.2e-32 111.7 0.0 0.11 12.4 0.0 24.0 26 0 0 26 26 26 4 TIG domain Anth_Ig PF05587.13 EKX41895.1 - 6.3e-23 81.0 7.3 0.018 15.3 0.0 14.3 16 0 0 16 16 16 6 Anthrax receptor extracellular domain HCV_NS4a PF01006.20 EKX41895.1 - 0.0056 16.4 0.3 12 5.8 0.0 3.9 2 0 0 2 2 2 2 Hepatitis C virus non-structural protein NS4a RHD_dimer PF16179.5 EKX41895.1 - 0.058 13.4 0.0 21 5.2 0.0 4.9 3 0 0 3 3 3 0 Rel homology dimerisation domain TIG PF01833.24 EKX41896.1 - 1e-61 205.0 45.5 2e-09 37.4 0.0 10.4 10 1 0 10 10 10 10 IPT/TIG domain TIG_plexin PF17960.1 EKX41896.1 - 1.5e-12 47.4 0.0 3 7.9 0.0 8.9 10 0 0 10 10 10 3 TIG domain Anth_Ig PF05587.13 EKX41896.1 - 5.1e-09 36.4 0.0 1.2 9.5 0.0 5.6 5 0 0 5 5 5 3 Anthrax receptor extracellular domain HCV_NS4a PF01006.20 EKX41896.1 - 0.0011 18.7 1.4 3.4 7.5 0.1 3.8 3 0 0 3 3 3 2 Hepatitis C virus non-structural protein NS4a TIG PF01833.24 EKX41897.1 - 7.6e-127 413.7 114.3 1.8e-07 31.2 0.1 26.1 28 0 0 28 28 28 22 IPT/TIG domain TIG_plexin PF17960.1 EKX41897.1 - 5e-23 80.9 24.7 0.39 10.7 0.0 18.2 21 0 0 21 21 21 10 TIG domain p6 PF17548.2 EKX41897.1 - 0.13 12.3 0.1 0.31 11.0 0.1 1.6 1 0 0 1 1 1 0 Histone-like Protein p6 TIG PF01833.24 EKX41898.1 - 4.2e-65 215.8 69.8 1.3e-10 41.2 0.4 12.0 11 2 0 11 11 11 11 IPT/TIG domain TIG_plexin PF17960.1 EKX41898.1 - 3.2e-07 30.2 4.8 5.3 7.1 0.0 6.2 6 0 0 6 6 6 2 TIG domain UnbV_ASPIC PF07593.12 EKX41898.1 - 0.011 15.7 0.3 10 6.2 0.0 3.2 2 0 0 2 2 2 0 ASPIC and UnbV zf-primase PF09329.11 EKX41898.1 - 0.038 13.8 0.1 14 5.6 0.0 2.4 2 0 0 2 2 2 0 Primase zinc finger Mtf2_C PF14061.6 EKX41898.1 - 0.057 13.6 0.0 1.2e+02 2.9 0.0 3.4 3 0 0 3 3 3 0 Polycomb-like MTF2 factor 2 Lipase_C PF18067.1 EKX41898.1 - 0.16 12.6 0.1 37 5.0 0.0 2.5 2 0 0 2 2 2 0 Lipase C-terminal domain Peptidase_U32_C PF16325.5 EKX41898.1 - 0.19 12.0 0.0 39 4.6 0.0 2.5 2 0 0 2 2 2 0 Peptidase family U32 C-terminal domain TIG PF01833.24 EKX41899.1 - 1.3e-11 44.4 0.0 1.4e-11 44.3 0.0 1.0 1 0 0 1 1 1 1 IPT/TIG domain TIG PF01833.24 EKX41900.1 - 1.6e-12 47.3 0.8 1.8e-12 47.2 0.8 1.0 1 0 0 1 1 1 1 IPT/TIG domain TIG_plexin PF17960.1 EKX41900.1 - 0.034 14.1 0.0 0.038 14.0 0.0 1.2 1 0 0 1 1 1 0 TIG domain Ephrin_rec_like PF07699.13 EKX41901.1 - 1.6e-07 30.9 19.6 1.7e-05 24.5 1.0 7.3 5 3 3 8 8 8 4 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX41901.1 - 0.064 13.7 31.1 0.14 12.6 1.5 7.1 4 3 3 7 7 7 0 TNFR/NGFR cysteine-rich region Lustrin_cystein PF14625.6 EKX41901.1 - 0.12 12.8 0.1 0.12 12.8 0.1 9.6 3 2 5 8 8 8 0 Lustrin, cysteine-rich repeated domain Whib PF02467.16 EKX41901.1 - 0.21 12.2 9.4 0.31 11.6 1.0 3.1 3 0 0 3 3 3 0 Transcription factor WhiB DUF4084 PF13321.6 EKX41902.1 - 0.18 11.3 7.0 0.26 10.8 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4084) DGF-1_C PF11040.8 EKX41902.1 - 1.8 8.6 5.0 2.6 8.1 2.1 2.7 2 1 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF5131 PF07505.11 EKX41903.1 - 0.19 11.1 0.4 0.43 10.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF5131) Peptidase_S10 PF00450.22 EKX41905.1 - 4.4e-105 352.5 0.1 5e-105 352.3 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 EKX41906.1 - 3.8e-11 44.0 0.5 4.3e-11 43.8 0.5 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EKX41906.1 - 2.1e-05 24.7 0.0 2.6e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 EKX41906.1 - 4.9e-05 22.7 0.0 0.00063 19.1 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 UPF0227 PF05728.12 EKX41906.1 - 0.00024 21.1 0.0 0.00028 20.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_1 PF00561.20 EKX41906.1 - 0.0003 20.5 0.8 0.004 16.8 0.8 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 EKX41906.1 - 0.00087 19.2 0.0 0.00099 19.0 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Ser_hydrolase PF06821.13 EKX41906.1 - 0.02 14.7 0.1 0.028 14.3 0.1 1.3 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_3 PF07859.13 EKX41906.1 - 0.12 12.2 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 EKX41906.1 - 0.16 11.6 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Putative esterase CENP-F_leu_zip PF10473.9 EKX41907.1 - 0.00047 20.2 16.4 0.00047 20.2 16.4 3.7 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4055 PF13264.6 EKX41907.1 - 0.004 17.3 2.9 0.004 17.3 2.9 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4055) TAFH PF07531.14 EKX41907.1 - 0.0079 16.3 1.4 0.098 12.8 0.3 2.9 2 0 0 2 2 2 1 NHR1 homology to TAF YscO PF07321.12 EKX41907.1 - 0.0086 16.0 3.2 0.0086 16.0 3.2 4.3 1 1 3 5 5 5 2 Type III secretion protein YscO SOAR PF16533.5 EKX41907.1 - 0.02 14.8 4.0 0.02 14.8 4.0 3.9 1 1 3 4 4 4 0 STIM1 Orai1-activating region Curto_V2 PF07325.11 EKX41907.1 - 0.51 10.2 3.6 0.4 10.6 0.1 2.2 2 0 0 2 2 2 0 Curtovirus V2 protein CALCOCO1 PF07888.11 EKX41907.1 - 0.7 8.7 43.6 0.048 12.5 26.7 2.1 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Golgin_A5 PF09787.9 EKX41907.1 - 2.3 7.6 44.2 0.51 9.8 16.8 3.2 1 1 2 3 3 3 0 Golgin subfamily A member 5 Baculo_PEP_C PF04513.12 EKX41907.1 - 2.8 8.0 10.7 14 5.7 0.0 3.6 2 2 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.11 EKX41907.1 - 3.6 7.8 46.4 2.2 8.5 9.1 4.7 1 1 4 5 5 5 0 Autophagy protein 16 (ATG16) HIP1_clath_bdg PF16515.5 EKX41907.1 - 9.5 6.9 48.0 2.5 8.8 5.7 5.2 1 1 4 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Solute_trans_a PF03619.16 EKX41908.1 - 4.2e-87 292.0 16.2 4.7e-87 291.9 16.2 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha SID-1_RNA_chan PF13965.6 EKX41911.1 - 0.0095 14.4 0.1 0.017 13.6 0.1 1.3 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 WBS_methylT PF12589.8 EKX41912.1 - 0.016 15.9 1.4 0.058 14.2 1.4 1.9 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome MMR_HSR1 PF01926.23 EKX41914.1 - 4.8e-16 58.8 0.4 4.2e-14 52.6 0.1 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EKX41914.1 - 3.7e-11 42.8 0.3 4.9e-07 29.4 0.1 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EKX41914.1 - 2.5e-07 30.7 0.9 0.006 16.5 0.2 2.3 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EKX41914.1 - 1.2e-05 25.0 0.0 0.038 13.5 0.0 2.8 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EKX41914.1 - 0.00015 21.9 0.9 0.0042 17.2 0.2 2.7 2 1 0 2 2 2 1 Dynamin family AIG1 PF04548.16 EKX41914.1 - 0.00029 20.2 0.2 0.00087 18.7 0.1 1.7 2 0 0 2 2 2 1 AIG1 family Roc PF08477.13 EKX41914.1 - 0.00038 20.7 0.2 0.05 13.8 0.1 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 EKX41914.1 - 0.00049 19.7 0.2 0.52 9.9 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 EKX41914.1 - 0.002 17.5 0.1 0.0073 15.6 0.0 1.7 2 0 0 2 2 2 1 Septin SRPRB PF09439.10 EKX41914.1 - 0.0022 17.4 0.0 0.0037 16.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EKX41914.1 - 0.0035 17.0 0.1 1.3 8.6 0.0 2.2 2 0 0 2 2 2 2 Ras family MeaB PF03308.16 EKX41914.1 - 0.01 14.9 0.2 0.047 12.7 0.1 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EKX41914.1 - 0.012 16.0 0.1 0.099 13.0 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain HTH_25 PF13413.6 EKX41915.1 - 1.5 8.7 5.4 0.24 11.3 0.3 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain Dicty_REP PF05086.12 EKX41915.1 - 7.5 4.4 6.5 10 4.0 6.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein V_ATPase_I PF01496.19 EKX41915.1 - 7.5 4.3 5.7 7.4 4.3 5.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TRAP_alpha PF03896.16 EKX41915.1 - 7.6 5.6 10.1 1.7 7.7 6.8 1.6 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit zf-4CXXC_R1 PF10497.9 EKX41916.1 - 0.0011 19.2 19.0 0.0025 18.0 19.0 1.6 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 EFP_N PF08207.12 EKX41917.1 - 8.2e-27 93.0 0.2 8.2e-27 93.0 0.2 2.2 4 0 0 4 4 4 1 Elongation factor P (EF-P) KOW-like domain Elong-fact-P_C PF09285.11 EKX41917.1 - 2.6e-26 91.1 1.0 6.6e-26 89.8 1.0 1.7 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP PF01132.20 EKX41917.1 - 3.8e-16 58.9 0.8 1.5e-15 57.0 0.8 1.9 2 0 0 2 2 2 1 Elongation factor P (EF-P) OB domain Myb_DNA-binding PF00249.31 EKX41918.1 - 8.2e-11 41.9 0.0 9.9e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX41918.1 - 0.066 13.5 0.0 0.077 13.2 0.0 1.2 1 0 0 1 1 1 0 Myb-like DNA-binding domain Glyco_hydro_31 PF01055.26 EKX41921.1 - 1.3e-67 228.9 0.1 1.8e-67 228.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF5110 PF17137.4 EKX41921.1 - 8.6e-08 32.4 0.0 1.6e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) DUF4968 PF16338.5 EKX41921.1 - 0.0078 16.5 0.1 0.018 15.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Pentapeptide_4 PF13599.6 EKX41921.1 - 0.13 12.5 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) bZIP_1 PF00170.21 EKX41922.1 - 0.2 11.8 11.2 0.38 10.9 11.2 1.4 1 0 0 1 1 1 0 bZIP transcription factor CDC45 PF02724.14 EKX41922.1 - 2.9 6.1 6.8 4.8 5.3 6.8 1.2 1 0 0 1 1 1 0 CDC45-like protein SNF2_N PF00176.23 EKX41924.1 - 3e-88 295.9 0.0 5.1e-88 295.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-CHY PF05495.12 EKX41924.1 - 0.15 12.6 3.0 8.4 7.0 0.1 2.7 2 0 0 2 2 2 0 CHY zinc finger Anoctamin PF04547.12 EKX41925.1 - 2.2e-73 247.7 5.8 2.4e-73 247.5 5.8 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Cytadhesin_P30 PF07271.11 EKX41925.1 - 0.15 11.6 0.1 0.2 11.2 0.1 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 Peptidase_M3 PF01432.20 EKX41926.1 - 2.1e-19 70.2 8.8 3.7e-18 66.0 8.8 2.0 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M3_N PF08439.10 EKX41926.1 - 1.3e-09 38.1 0.2 3.8e-09 36.7 0.2 1.8 1 0 0 1 1 1 1 Oligopeptidase F Peptidase_M78 PF06114.13 EKX41926.1 - 0.0016 18.4 0.0 0.0058 16.6 0.0 1.9 2 0 0 2 2 2 1 IrrE N-terminal-like domain MTBP_N PF14918.6 EKX41926.1 - 0.0023 17.5 2.5 0.0066 16.0 0.0 2.5 3 0 0 3 3 3 1 MDM2-binding DUF1802 PF08819.11 EKX41926.1 - 0.069 13.0 0.4 0.13 12.1 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1802) Reprolysin_3 PF13582.6 EKX41926.1 - 0.079 13.5 0.1 0.19 12.2 0.1 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like OrfA PF17495.2 EKX41926.1 - 0.099 12.8 0.1 26 5.0 0.0 3.7 4 0 0 4 4 4 0 Vpr-like OrfA LRR_4 PF12799.7 EKX41927.1 - 4.9e-14 52.2 17.9 1.1e-05 25.7 0.1 5.3 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX41927.1 - 1.4e-12 47.2 15.9 1.2e-05 24.9 2.4 4.3 3 1 0 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 EKX41927.1 - 1.6e-09 37.5 7.8 7.3e-08 32.1 1.0 2.2 1 1 1 2 2 2 2 Leucine-rich repeat DUF4586 PF15239.6 EKX41927.1 - 1.6e-06 28.6 5.5 2.4e-06 27.9 5.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) LRR_6 PF13516.6 EKX41927.1 - 0.31 11.2 18.1 14 6.1 0.0 6.3 8 0 0 8 8 8 0 Leucine Rich repeat DUF4336 PF14234.6 EKX41929.1 - 2.3e-59 201.2 0.2 2.1e-42 145.5 0.1 3.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) Runt PF00853.19 EKX41930.1 - 0.0059 16.2 0.1 7.3 6.2 0.0 3.6 3 0 0 3 3 3 2 Runt domain Ephrin_rec_like PF07699.13 EKX41930.1 - 0.76 9.6 10.1 2.8 7.8 10.1 2.1 1 0 0 1 1 1 0 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX41930.1 - 1.5 9.3 8.5 6.1 7.3 8.5 2.1 1 0 0 1 1 1 0 TNFR/NGFR cysteine-rich region EGF_CA PF07645.15 EKX41931.1 - 1.4e-17 63.6 28.0 6.5e-10 39.1 5.8 4.6 4 0 0 4 4 4 3 Calcium-binding EGF domain EGF_3 PF12947.7 EKX41931.1 - 2.5e-14 53.2 28.7 1.3e-09 38.1 7.3 4.3 4 0 0 4 4 4 2 EGF domain cEGF PF12662.7 EKX41931.1 - 2.1e-10 40.3 21.1 6.6e-05 22.8 0.7 5.0 5 0 0 5 5 5 4 Complement Clr-like EGF-like LysM PF01476.20 EKX41931.1 - 1.8e-09 37.5 0.3 0.00019 21.4 0.0 3.5 2 1 0 2 2 2 2 LysM domain EGF_MSP1_1 PF12946.7 EKX41931.1 - 4.9e-06 26.5 17.6 3.4e-05 23.8 2.6 4.0 4 0 0 4 4 4 2 MSP1 EGF domain 1 EGF PF00008.27 EKX41931.1 - 0.00044 20.5 8.1 0.00044 20.5 8.1 4.0 3 1 1 4 4 4 2 EGF-like domain hEGF PF12661.7 EKX41931.1 - 0.0048 17.5 3.7 0.0048 17.5 3.7 5.8 5 1 1 6 6 6 2 Human growth factor-like EGF FXa_inhibition PF14670.6 EKX41931.1 - 1.4 9.3 35.0 0.34 11.2 8.2 4.6 2 2 1 3 3 3 0 Coagulation Factor Xa inhibitory site Pkinase PF00069.25 EKX41932.1 - 6e-18 65.2 0.1 6e-18 65.2 0.1 2.9 3 1 1 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX41932.1 - 1.6e-08 34.1 0.2 5.3e-08 32.5 0.2 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase Peripla_BP_4 PF13407.6 EKX41932.1 - 0.16 11.5 0.3 0.32 10.5 0.3 1.5 1 0 0 1 1 1 0 Periplasmic binding protein domain Baculo_PEP_C PF04513.12 EKX41932.1 - 0.2 11.7 6.5 4.5 7.3 0.4 2.6 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Presenilin PF01080.17 EKX41932.1 - 2.6 6.7 25.9 6.2 5.5 25.9 1.6 1 0 0 1 1 1 0 Presenilin Sel1 PF08238.12 EKX41933.1 - 5.2e-68 224.0 23.4 1.9e-10 41.0 0.5 7.8 8 0 0 8 8 8 7 Sel1 repeat TPR_6 PF13174.6 EKX41933.1 - 4.2e-11 42.7 7.9 0.039 14.6 0.0 7.4 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX41933.1 - 7.4e-08 32.9 20.6 0.0013 19.4 0.4 6.1 2 1 3 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 EKX41933.1 - 2.4e-06 27.2 11.0 0.012 15.6 0.1 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat MIT PF04212.18 EKX41933.1 - 0.005 16.9 6.4 5.2 7.2 0.0 5.3 6 0 0 6 6 6 1 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 EKX41933.1 - 0.019 15.3 15.8 0.22 11.9 0.6 7.1 4 1 4 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX41933.1 - 0.051 14.4 11.0 20 6.3 0.3 5.7 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 EKX41933.1 - 0.39 10.4 17.1 5.1 6.9 0.3 7.1 7 2 1 8 8 8 0 TPR repeat TPR_2 PF07719.17 EKX41933.1 - 0.61 10.3 36.3 1.3 9.3 0.1 9.8 12 0 0 12 12 11 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX41933.1 - 0.98 9.8 24.2 4.9 7.6 0.2 8.0 8 1 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 EKX41933.1 - 5 7.1 41.7 2 8.4 0.1 10.5 12 0 0 12 12 12 0 Tetratricopeptide repeat TetR_C_18 PF17923.1 EKX41933.1 - 5.2 7.6 5.3 28 5.3 0.1 3.3 3 1 1 4 4 3 0 Tetracyclin repressor-like, C-terminal domain Binary_toxB_3 PF17476.2 EKX41934.1 - 0.093 12.9 0.1 0.31 11.3 0.1 1.9 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA domain 3 RRM_1 PF00076.22 EKX41935.1 - 5.3e-06 26.2 0.0 9.5e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 EKX41935.1 - 0.00033 20.5 2.4 0.00089 19.1 2.4 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EKX41935.1 - 0.0011 18.9 2.8 0.0011 18.9 2.8 2.1 2 0 0 2 2 2 1 Zinc finger domain RRM_occluded PF16842.5 EKX41935.1 - 0.0029 17.4 0.0 0.014 15.3 0.0 1.9 1 1 0 1 1 1 1 Occluded RNA-recognition motif DUF3473 PF11959.8 EKX41935.1 - 0.018 15.0 0.0 2 8.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3473) Torus PF16131.5 EKX41935.1 - 0.086 13.6 0.4 0.086 13.6 0.4 1.9 2 0 0 2 2 2 0 Torus domain NAD_binding_6 PF08030.12 EKX41936.1 - 8.8e-11 42.2 0.0 1.8e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EKX41936.1 - 4.1e-09 36.6 9.0 4.1e-09 36.6 9.0 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component Reeler PF02014.16 EKX41936.1 - 5.6e-05 23.9 0.0 0.00013 22.7 0.0 1.7 1 0 0 1 1 1 1 Reeler domain NAD_binding_1 PF00175.21 EKX41936.1 - 0.0077 16.9 0.0 0.014 16.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain LRR_4 PF12799.7 EKX41937.1 - 2.5e-12 46.8 44.3 0.0043 17.4 0.4 11.8 7 3 5 12 12 12 7 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EKX41937.1 - 1.9e-08 33.7 65.5 0.022 14.8 0.2 14.4 17 0 0 17 17 17 6 Leucine Rich repeat LRR_8 PF13855.6 EKX41937.1 - 1.4e-05 24.7 43.1 0.79 9.5 0.5 12.1 11 4 0 11 11 11 3 Leucine rich repeat F-box-like PF12937.7 EKX41937.1 - 0.00016 21.5 0.1 0.0043 16.9 0.0 3.0 2 0 0 2 2 2 1 F-box-like LRR_1 PF00560.33 EKX41937.1 - 0.0076 16.6 42.5 25 5.9 0.0 13.8 16 0 0 16 16 16 1 Leucine Rich Repeat Voltage_CLC PF00654.20 EKX41938.1 - 2.9e-83 280.1 21.5 6e-83 279.0 21.5 1.5 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 EKX41938.1 - 4.7e-08 33.4 0.0 0.0077 16.6 0.0 2.5 2 0 0 2 2 2 2 CBS domain CAAD PF14159.6 EKX41938.1 - 0.11 12.4 0.0 0.75 9.7 0.0 2.4 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase TAT_signal PF10518.9 EKX41938.1 - 0.19 11.7 13.3 0.083 12.8 2.2 3.0 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence DUF2046 PF09755.9 EKX41940.1 - 1.9e-19 70.0 70.5 2.6e-11 43.3 15.7 4.2 1 1 3 4 4 4 4 Uncharacterized conserved protein H4 (DUF2046) Rootletin PF15035.6 EKX41940.1 - 4.6 7.2 63.5 3.2 7.7 31.9 2.8 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.9 EKX41940.1 - 5.6 7.0 77.5 3.4 7.7 18.0 5.6 1 1 4 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Acid_PPase PF12689.7 EKX41941.1 - 9.8e-40 136.2 0.1 6.9e-39 133.4 0.1 1.9 1 1 0 1 1 1 1 Acid Phosphatase NIF PF03031.18 EKX41941.1 - 0.00077 19.3 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.26 EKX41941.1 - 0.001 19.4 0.1 0.28 11.4 0.1 2.0 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 EKX41941.1 - 0.029 13.9 0.0 0.73 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) PNK3P PF08645.11 EKX41941.1 - 0.082 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase RNase_T PF00929.24 EKX41943.1 - 2.2e-10 41.3 0.2 4.1e-10 40.4 0.2 1.4 1 1 0 1 1 1 1 Exonuclease TPR_2 PF07719.17 EKX41944.1 - 0.00015 21.6 0.1 0.18 12.0 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX41944.1 - 0.00016 21.3 0.1 0.22 11.4 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX41944.1 - 0.0011 19.2 0.1 0.0014 18.9 0.1 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX41944.1 - 0.003 18.0 0.1 0.0033 17.9 0.1 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX41944.1 - 0.0057 17.4 0.1 0.97 10.4 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat Ion_trans PF00520.31 EKX41946.1 - 3.5e-33 114.8 24.2 5.6e-33 114.2 24.2 1.2 1 0 0 1 1 1 1 Ion transport protein EF-hand_1 PF00036.32 EKX41946.1 - 4.8e-05 22.6 0.0 0.00014 21.1 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 EKX41946.1 - 0.00011 21.6 0.9 0.00054 19.3 0.1 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EKX41946.1 - 0.00029 20.5 0.1 0.0012 18.6 0.1 2.2 1 0 0 1 1 1 1 EF-hand domain PH PF00169.29 EKX41946.1 - 0.00075 20.0 0.3 0.0025 18.3 0.3 1.9 1 1 0 1 1 1 1 PH domain EF-hand_7 PF13499.6 EKX41946.1 - 0.00083 19.8 0.5 0.0098 16.3 0.0 2.9 3 0 0 3 3 2 1 EF-hand domain pair EF-hand_8 PF13833.6 EKX41946.1 - 0.014 15.2 0.0 0.052 13.4 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair RPN7 PF10602.9 EKX41946.1 - 0.085 12.6 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 26S proteasome subunit RPN7 RPA43_OB PF17875.1 EKX41946.1 - 0.26 11.9 4.4 0.58 10.8 4.4 1.6 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I PTPRCAP PF15713.5 EKX41946.1 - 0.27 11.5 13.4 0.79 10.0 13.4 1.7 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Spt20 PF12090.8 EKX41946.1 - 0.32 10.6 4.9 0.57 9.8 4.9 1.3 1 0 0 1 1 1 0 Spt20 family CPSF100_C PF13299.6 EKX41946.1 - 0.54 10.4 6.1 1.3 9.2 6.1 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 EKX41946.1 - 0.57 10.0 5.7 1.1 9.0 5.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM176 PF14851.6 EKX41946.1 - 1.2 8.8 8.6 4.8 6.8 8.6 2.0 1 0 0 1 1 1 0 FAM176 family Ribosomal_60s PF00428.19 EKX41946.1 - 1.2 9.7 7.8 0.17 12.5 3.3 1.9 2 0 0 2 2 1 0 60s Acidic ribosomal protein Paf1 PF03985.13 EKX41946.1 - 2 7.3 14.9 3.2 6.7 14.9 1.2 1 0 0 1 1 1 0 Paf1 CobT PF06213.12 EKX41946.1 - 3.5 7.0 17.3 6.4 6.1 17.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pox_Ag35 PF03286.14 EKX41946.1 - 4 7.2 10.6 7.7 6.3 10.6 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PH_13 PF16652.5 EKX41946.1 - 4.6 7.0 7.9 0.13 12.0 0.3 2.3 3 0 0 3 3 2 0 Pleckstrin homology domain CDC45 PF02724.14 EKX41946.1 - 6.2 5.0 12.5 9.6 4.4 12.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Roughex PF06020.11 EKX41946.1 - 6.2 5.8 9.9 10 5.1 9.9 1.3 1 0 0 1 1 1 0 Drosophila roughex protein RNA_pol_Rpc4 PF05132.14 EKX41946.1 - 7.7 6.9 8.2 17 5.8 8.2 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 CH PF00307.31 EKX41949.1 - 1.3e-10 41.4 0.0 1.6e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 EKX41949.1 - 1.7e-06 28.0 0.0 2.1e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 EKX41949.1 - 1.7e-05 24.6 0.0 2.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 CAMSAP CH domain HIM1 PF08732.10 EKX41952.1 - 0.039 13.5 0.0 0.041 13.4 0.0 1.0 1 0 0 1 1 1 0 HIM1 Rpr2 PF04032.16 EKX41952.1 - 0.057 13.7 0.0 0.064 13.5 0.0 1.2 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Acyltransferase PF01553.21 EKX41953.1 - 1 9.0 8.4 0.98 9.0 1.7 2.1 1 1 1 2 2 2 0 Acyltransferase NPR3 PF03666.13 EKX41953.1 - 3.8 6.2 8.0 1.4e+02 1.0 7.9 2.8 1 1 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 WD40 PF00400.32 EKX41954.1 - 3.8e-13 49.7 22.8 0.00011 22.9 0.1 7.6 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX41954.1 - 1.2e-10 41.5 6.5 0.003 17.8 0.1 6.3 4 1 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 EKX41954.1 - 5.1e-07 28.1 0.6 0.0062 14.6 0.0 3.1 2 1 1 3 3 3 2 IKI3 family PD40 PF07676.12 EKX41954.1 - 0.00094 19.1 1.3 0.082 12.9 0.1 3.2 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EKX41954.1 - 0.03 13.3 0.4 2.1 7.2 0.0 3.2 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 EKX41954.1 - 0.061 12.4 3.0 3.6 6.5 0.3 3.1 3 1 0 3 3 3 0 Coatomer WD associated region Clathrin PF00637.20 EKX41954.1 - 0.12 12.3 0.1 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS TMP-TENI PF02581.17 EKX41955.1 - 9.9e-18 64.1 0.0 1.3e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Thiamine monophosphate synthase Aldolase PF01081.19 EKX41955.1 - 0.14 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 KDPG and KHG aldolase LNS2 PF08235.13 EKX41957.1 - 2.6e-53 180.8 0.0 3e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) DUF2563 PF10817.8 EKX41957.1 - 0.027 15.1 0.0 0.054 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2563) Hydrolase_6 PF13344.6 EKX41957.1 - 0.043 13.9 0.0 0.079 13.1 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 EKX41957.1 - 0.15 11.5 0.3 2 7.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2608) DUF3090 PF11290.8 EKX41957.1 - 0.16 11.7 0.0 1.6 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) 2-Hacid_dh_C PF02826.19 EKX41959.1 - 3.2e-24 85.3 0.0 5.7e-24 84.4 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EKX41959.1 - 5.7e-11 42.2 0.0 7.2e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ThiF PF00899.21 EKX41959.1 - 0.011 15.1 0.2 0.023 14.0 0.1 1.6 2 0 0 2 2 2 0 ThiF family NAD_binding_2 PF03446.15 EKX41959.1 - 0.025 14.7 0.0 0.058 13.6 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Tachystatin_B PF11478.8 EKX41959.1 - 0.13 12.2 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Antimicrobial chitin binding protein tachystatin B Syja_N PF02383.18 EKX41961.1 - 7.4e-68 229.2 0.0 1.4e-67 228.3 0.0 1.5 2 0 0 2 2 2 1 SacI homology domain 5_nucleotid PF05761.14 EKX41962.1 - 3.8e-120 401.9 2.8 9.8e-91 304.9 0.5 2.1 1 1 1 2 2 2 2 5' nucleotidase family HAD_2 PF13419.6 EKX41962.1 - 0.0047 17.0 0.1 0.028 14.5 0.1 2.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EKX41962.1 - 0.041 14.0 0.0 0.088 12.9 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like PGP_phosphatase PF09419.10 EKX41962.1 - 0.044 13.4 0.1 1.1 8.8 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial PGP phosphatase His_Phos_1 PF00300.22 EKX41963.1 - 1.3e-17 64.1 2.0 3.3e-17 62.8 2.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Cyclin PF08613.11 EKX41964.1 - 1e-27 97.5 0.1 1.9e-27 96.6 0.1 1.5 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EKX41964.1 - 2.3e-05 24.1 0.0 3.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain FAD_syn PF06574.12 EKX41964.1 - 0.066 13.1 0.1 0.17 11.8 0.1 1.7 2 0 0 2 2 2 0 FAD synthetase Spc42p PF11544.8 EKX41967.1 - 0.0006 19.8 3.7 0.0014 18.5 3.1 2.0 1 1 0 1 1 1 1 Spindle pole body component Spc42p Cep57_CLD PF14073.6 EKX41967.1 - 0.0023 18.0 10.8 0.0042 17.1 10.8 1.4 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 DUF641 PF04859.12 EKX41967.1 - 0.0025 18.1 2.4 0.0056 17.0 2.4 1.6 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) DUF4686 PF15742.5 EKX41967.1 - 0.012 14.8 10.5 0.017 14.3 10.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) Tropomyosin_1 PF12718.7 EKX41967.1 - 0.022 14.9 8.1 0.022 14.9 8.1 1.7 2 0 0 2 2 1 0 Tropomyosin like Atg14 PF10186.9 EKX41967.1 - 0.039 13.0 5.3 0.048 12.7 5.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GAS PF13851.6 EKX41967.1 - 0.061 12.7 7.4 0.1 11.9 7.4 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.11 EKX41967.1 - 0.07 12.9 0.7 0.12 12.2 0.7 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 ADIP PF11559.8 EKX41967.1 - 0.11 12.6 7.7 0.091 12.8 5.0 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 EKX41967.1 - 0.12 11.8 16.3 0.068 12.6 11.5 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF2478 PF10649.9 EKX41967.1 - 0.16 11.6 0.9 0.46 10.1 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2478) MPS2 PF17060.5 EKX41967.1 - 0.21 10.8 3.9 0.32 10.2 3.9 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 Syntaxin-6_N PF09177.11 EKX41967.1 - 0.22 12.1 5.9 0.39 11.3 4.5 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal UPF0242 PF06785.11 EKX41967.1 - 0.23 11.6 7.0 0.39 10.8 7.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus USP8_interact PF08941.10 EKX41967.1 - 0.23 11.2 2.8 0.4 10.5 2.8 1.5 1 0 0 1 1 1 0 USP8 interacting SlyX PF04102.12 EKX41967.1 - 0.25 12.0 10.8 0.27 11.9 7.1 2.6 2 0 0 2 2 2 0 SlyX DUF4665 PF15679.5 EKX41967.1 - 0.25 12.0 0.9 5.9 7.6 1.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4665) DUF1664 PF07889.12 EKX41967.1 - 0.75 9.8 4.3 3.7 7.6 2.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Rootletin PF15035.6 EKX41967.1 - 1 9.4 14.0 0.54 10.3 11.1 1.9 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Fez1 PF06818.15 EKX41967.1 - 1 9.8 14.9 1.7 9.0 14.9 1.6 1 1 0 1 1 1 0 Fez1 Spc7 PF08317.11 EKX41967.1 - 1.2 8.0 9.4 0.23 10.3 5.5 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF724 PF05266.14 EKX41967.1 - 1.2 8.9 5.5 1.1 9.0 4.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF724) ATG16 PF08614.11 EKX41967.1 - 1.4 9.2 14.6 3.4 7.8 9.7 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Csm1_N PF18504.1 EKX41967.1 - 3 8.2 11.5 1.7 9.0 7.5 2.5 2 1 0 2 2 2 0 Csm1 N-terminal domain APG6_N PF17675.1 EKX41967.1 - 4.8 7.7 15.8 8.9 6.8 12.5 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region Nop14 PF04147.12 EKX41969.1 - 0.038 12.2 20.4 0.05 11.8 20.4 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EKX41969.1 - 0.077 12.4 19.4 0.12 11.8 19.4 1.4 1 0 0 1 1 1 0 SDA1 DUF3040 PF11239.8 EKX41969.1 - 0.081 13.2 0.8 0.29 11.4 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) BUD22 PF09073.10 EKX41969.1 - 0.28 10.5 19.9 0.42 9.9 19.9 1.3 1 0 0 1 1 1 0 BUD22 YL1 PF05764.13 EKX41969.1 - 0.7 10.0 17.3 1.2 9.2 17.3 1.5 1 0 0 1 1 1 0 YL1 nuclear protein RRN3 PF05327.11 EKX41969.1 - 3.1 6.2 16.2 4.3 5.8 16.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 EKX41969.1 - 5.5 5.1 20.1 7 4.8 20.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 EKX41969.1 - 8.5 4.3 34.2 2.1 6.3 30.9 1.5 2 0 0 2 2 2 0 DNA polymerase phi GCIP PF13324.6 EKX41969.1 - 9.5 5.7 11.3 72 2.9 12.8 1.7 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting zf-CCCH PF00642.24 EKX41970.1 - 8.5e-19 67.0 17.9 8.4e-10 38.3 3.1 2.1 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EKX41970.1 - 2e-13 49.8 15.2 7.4e-09 35.2 1.9 2.2 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EKX41970.1 - 2.3e-13 49.7 18.5 1.5e-07 31.2 2.8 2.2 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_2 PF14608.6 EKX41970.1 - 1.8e-06 28.2 16.6 0.0062 17.0 1.7 2.3 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 EKX41970.1 - 0.00034 21.3 12.6 0.0037 18.0 1.2 2.0 1 1 1 2 2 2 2 Torus domain oligo_HPY PF08352.12 EKX41970.1 - 2.3 8.8 8.2 1.2 9.8 1.0 2.1 1 1 1 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region DUF456 PF04306.13 EKX41971.1 - 0.0069 16.7 1.7 0.0069 16.7 1.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF456) Bacteriocin_IIc PF10439.9 EKX41971.1 - 0.19 11.9 9.6 1.6 8.9 5.8 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide HECT PF00632.25 EKX41972.1 - 1.2e-47 162.9 0.0 1.3e-47 162.8 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) FGase PF05013.12 EKX41974.1 - 0.028 14.6 0.0 0.051 13.8 0.0 1.3 1 0 0 1 1 1 0 N-formylglutamate amidohydrolase BING4CT PF08149.11 EKX41975.1 - 3e-33 113.5 0.0 3e-33 113.5 0.0 2.5 3 0 0 3 3 3 1 BING4CT (NUC141) domain Bac_rhodopsin PF01036.18 EKX41976.1 - 1.8e-12 47.3 7.8 3.7e-12 46.3 7.8 1.4 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Syntaxin_2 PF14523.6 EKX41976.1 - 0.045 14.1 0.5 0.073 13.4 0.5 1.3 1 0 0 1 1 1 0 Syntaxin-like protein Csm1_N PF18504.1 EKX41976.1 - 0.098 13.0 2.0 0.16 12.3 2.0 1.3 1 0 0 1 1 1 0 Csm1 N-terminal domain SlyX PF04102.12 EKX41976.1 - 0.37 11.5 1.9 0.62 10.7 1.9 1.3 1 0 0 1 1 1 0 SlyX DcpS_C PF11969.8 EKX41977.1 - 7.5e-24 84.4 0.3 1.4e-23 83.5 0.3 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 EKX41977.1 - 4.5e-09 37.1 0.0 8.8e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Proteasome PF00227.26 EKX41978.1 - 2.3e-64 216.4 0.1 4e-64 215.6 0.0 1.4 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 EKX41978.1 - 9.2e-11 41.2 0.3 2.5e-10 39.8 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature cNMP_binding PF00027.29 EKX41979.1 - 2.5e-06 27.5 0.0 7.3e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Imm49 PF15575.6 EKX41979.1 - 0.041 13.7 0.2 0.14 11.9 0.2 1.9 1 0 0 1 1 1 0 Immunity protein 49 UPF0061 PF02696.14 EKX41979.1 - 0.16 10.7 2.1 0.28 9.9 2.1 1.3 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family RNase_H2_suC PF08615.11 EKX41979.1 - 1.6 8.9 7.4 36 4.5 0.6 3.5 3 0 0 3 3 3 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF4820 PF16091.5 EKX41979.1 - 3.8 6.8 18.8 0.41 10.0 2.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4820) NIR_SIR PF01077.22 EKX41980.1 - 1.6e-57 193.5 0.0 1.6e-42 144.7 0.0 2.6 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 EKX41980.1 - 1.2e-33 114.7 0.0 3.5e-17 62.0 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Muted PF14942.6 EKX41980.1 - 0.12 12.7 1.0 0.27 11.6 1.0 1.5 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein EF-hand_7 PF13499.6 EKX41981.1 - 1.7e-23 82.9 14.3 1.1e-09 38.6 3.7 4.0 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EKX41981.1 - 1.5e-16 58.6 20.3 5.1e-05 22.5 0.6 6.6 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 EKX41981.1 - 2e-15 55.4 16.8 5.3e-06 25.9 0.2 6.7 6 0 0 6 6 6 4 EF-hand domain EF-hand_8 PF13833.6 EKX41981.1 - 5.8e-09 35.7 10.5 0.00019 21.2 2.8 4.2 3 1 0 3 3 3 2 EF-hand domain pair cNMP_binding PF00027.29 EKX41981.1 - 6.6e-08 32.5 0.0 1.4e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain EF-hand_9 PF14658.6 EKX41981.1 - 0.00035 20.8 3.4 0.00095 19.4 0.2 3.4 5 0 0 5 5 5 1 EF-hand domain EF-hand_5 PF13202.6 EKX41981.1 - 0.00047 19.5 23.4 0.057 12.9 0.5 6.4 6 0 0 6 6 6 2 EF hand SPARC_Ca_bdg PF10591.9 EKX41981.1 - 0.0017 18.7 4.1 0.31 11.4 0.0 4.4 4 1 0 4 4 4 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EKX41981.1 - 0.0076 16.2 8.9 0.26 11.2 0.2 4.5 4 1 1 5 5 5 1 Cytoskeletal-regulatory complex EF hand Syntaxin PF00804.25 EKX41981.1 - 0.016 14.9 0.9 5.3 6.7 0.0 3.4 3 0 0 3 3 3 0 Syntaxin DUF1456 PF07308.13 EKX41981.1 - 0.036 14.4 0.4 20 5.6 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1456) Metallothio_2 PF01439.18 EKX41981.1 - 0.1 13.5 2.4 0.28 12.1 0.0 2.9 3 0 0 3 3 3 0 Metallothionein HEPN_Cthe2314 PF18730.1 EKX41981.1 - 0.21 11.6 2.7 0.62 10.1 2.7 1.8 1 0 0 1 1 1 0 Cthe_2314-like HEPN Mem_trans PF03547.18 EKX41982.1 - 4.9e-39 133.8 12.3 1.5e-26 92.7 0.4 2.0 1 1 1 2 2 2 2 Membrane transport protein Glycos_transf_2 PF00535.26 EKX41983.1 - 3.1e-28 98.7 0.0 4.1e-28 98.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EKX41983.1 - 4e-05 23.6 0.0 5.8e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 NTP_transf_3 PF12804.7 EKX41983.1 - 0.00014 22.2 0.0 0.00017 22.0 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Glyco_tranf_2_2 PF10111.9 EKX41983.1 - 0.01 15.3 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Polysacc_deac_1 PF01522.21 EKX41983.1 - 0.13 12.2 0.0 0.74 9.7 0.0 2.0 1 1 1 3 3 3 0 Polysaccharide deacetylase AAA_22 PF13401.6 EKX41983.1 - 0.16 12.3 0.0 0.38 11.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain BAF250_C PF12031.8 EKX41984.1 - 0.074 12.3 0.7 0.09 12.1 0.0 1.6 2 0 0 2 2 2 0 SWI/SNF-like complex subunit BAF250/Osa DUF4116 PF13475.6 EKX41985.1 - 3.5e-57 189.9 0.0 7.5e-19 67.2 0.0 3.5 1 1 4 5 5 5 5 Domain of unknown function (DUF4116) NINJA_B PF16136.5 EKX41985.1 - 0.017 15.5 3.3 0.017 15.5 3.3 2.5 2 0 0 2 2 2 0 Putative nuclear localisation signal Rrp15p PF07890.12 EKX41985.1 - 0.1 12.9 0.3 0.23 11.8 0.3 1.6 1 0 0 1 1 1 0 Rrp15p Longin PF13774.6 EKX41986.1 - 2.4e-07 30.7 0.0 3.3e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Regulated-SNARE-like domain Cwf_Cwc_15 PF04889.12 EKX41986.1 - 0.053 13.3 19.3 0.065 13.0 19.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 EKX41986.1 - 0.21 10.9 23.0 0.25 10.6 23.0 1.1 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 EKX41986.1 - 0.28 11.4 22.0 0.31 11.2 22.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PPP4R2 PF09184.11 EKX41986.1 - 0.5 9.9 16.3 0.57 9.7 16.3 1.1 1 0 0 1 1 1 0 PPP4R2 CobT PF06213.12 EKX41986.1 - 0.82 9.0 11.4 0.89 8.9 11.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2457 PF10446.9 EKX41986.1 - 0.94 8.5 25.8 1 8.4 25.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 EKX41986.1 - 2.7 6.1 18.4 3 6.0 18.4 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EKX41986.1 - 2.9 6.1 14.6 2.9 6.1 14.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 EKX41986.1 - 4.1 5.4 11.1 4.2 5.3 11.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pkinase PF00069.25 EKX41987.1 - 3.6e-65 220.0 0.0 4.1e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX41987.1 - 8.1e-29 100.7 0.0 1.1e-28 100.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX41987.1 - 4.1e-07 29.6 0.0 4.3e-05 23.0 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.14 EKX41987.1 - 1.4e-06 27.8 0.4 2.8e-06 26.9 0.4 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX41987.1 - 8.5e-06 25.9 0.4 3.6e-05 23.8 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX41987.1 - 2.5e-05 23.2 0.1 8.3e-05 21.5 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase DUF2087 PF09860.9 EKX41987.1 - 0.0053 16.9 0.0 0.018 15.2 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2087) Choline_kinase PF01633.20 EKX41987.1 - 0.013 15.1 0.3 0.022 14.3 0.3 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 EKX41987.1 - 0.018 14.6 0.7 0.055 13.1 0.3 1.8 1 1 1 2 2 2 0 RIO1 family YrbL-PhoP_reg PF10707.9 EKX41987.1 - 0.082 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 EKX41987.1 - 0.63 9.6 2.3 0.48 10.0 0.3 1.8 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 XLF PF09302.11 EKX41989.1 - 0.39 10.9 8.3 0.4 10.8 0.3 3.0 1 1 2 3 3 3 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component GIT_CC PF16559.5 EKX41989.1 - 0.56 10.1 12.1 0.11 12.4 0.7 3.7 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Csm1_N PF18504.1 EKX41989.1 - 1.5 9.2 9.8 0.22 11.9 0.6 3.3 3 0 0 3 3 3 0 Csm1 N-terminal domain Tim17 PF02466.19 EKX41990.1 - 9.9e-09 35.6 7.9 1.5e-08 35.0 7.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Auxin_canalis PF05703.11 EKX41990.1 - 0.052 13.5 2.0 0.069 13.1 2.0 1.1 1 0 0 1 1 1 0 Auxin canalisation DUF3493 PF11998.8 EKX41990.1 - 5.1 7.3 6.4 11 6.3 0.9 2.4 2 1 0 2 2 2 0 Low psii accumulation1 / Rep27 Ion_trans PF00520.31 EKX41991.1 - 9.2e-148 490.1 83.7 2.2e-46 158.1 18.6 4.1 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 EKX41991.1 - 0.00033 19.5 0.6 0.00033 19.5 0.6 8.6 8 3 1 9 9 9 6 Polycystin cation channel Aldo_ket_red PF00248.21 EKX41993.1 - 3.1e-68 230.1 0.0 3.6e-68 229.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aha1_N PF09229.11 EKX41994.1 - 1.8e-09 37.9 0.0 2.2e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal UCH PF00443.29 EKX41995.1 - 3.7e-17 62.7 0.0 4.2e-14 52.7 0.0 2.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 EKX41995.1 - 0.00012 21.9 0.0 0.00032 20.5 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain UCH_1 PF13423.6 EKX41995.1 - 0.047 13.3 0.0 0.15 11.6 0.0 1.8 1 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase DUF2155 PF09923.9 EKX41996.1 - 0.073 13.3 2.1 0.27 11.5 0.3 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2155) Zn_clus PF00172.18 EKX41997.1 - 1.5e-18 66.6 24.1 2.2e-09 37.3 8.0 2.2 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Dynein_light PF01221.18 EKX41998.1 - 6.9e-22 77.6 0.1 8.1e-22 77.3 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Nop PF01798.18 EKX41998.1 - 0.043 13.3 0.0 0.052 13.0 0.0 1.1 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin COG2 PF06148.11 EKX41999.1 - 6 7.0 8.6 1.4 9.0 0.9 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 AMP-binding PF00501.28 EKX42000.1 - 5.1e-25 87.9 0.0 2.7e-23 82.2 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme PQQ_3 PF13570.6 EKX42000.1 - 3.9e-08 33.5 2.8 0.012 16.1 0.3 5.6 4 1 0 4 4 4 2 PQQ-like domain PQQ_2 PF13360.6 EKX42000.1 - 0.011 15.4 0.0 0.2 11.2 0.0 2.5 1 1 1 2 2 2 0 PQQ-like domain ABC_membrane PF00664.23 EKX42001.1 - 5.9e-61 206.5 4.3 7.2e-30 104.6 0.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EKX42001.1 - 6.3e-54 182.2 0.0 2.4e-29 102.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EKX42001.1 - 3.6e-12 46.2 0.4 0.0068 15.9 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EKX42001.1 - 6.3e-07 29.5 0.1 0.062 13.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EKX42001.1 - 9.7e-07 28.8 0.5 0.007 16.3 0.0 3.2 3 0 0 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 EKX42001.1 - 1.6e-06 27.7 2.7 0.0017 18.1 0.3 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EKX42001.1 - 2.6e-06 27.5 0.1 0.029 14.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EKX42001.1 - 3.2e-05 24.4 0.2 0.37 11.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 EKX42001.1 - 8.5e-05 22.7 0.1 0.068 13.2 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.6 EKX42001.1 - 0.00018 22.1 8.4 0.036 14.6 0.2 3.2 3 1 1 4 4 3 2 AAA domain AAA_22 PF13401.6 EKX42001.1 - 0.00057 20.2 1.6 0.43 10.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.18 EKX42001.1 - 0.002 17.5 0.4 1.9 7.8 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family ABC_ATPase PF09818.9 EKX42001.1 - 0.0021 16.9 0.7 0.14 10.9 0.1 2.7 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_25 PF13481.6 EKX42001.1 - 0.0024 17.5 2.7 0.079 12.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain MeaB PF03308.16 EKX42001.1 - 0.011 14.7 0.4 3.3 6.6 0.0 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 EKX42001.1 - 0.014 15.2 0.9 0.93 9.1 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.19 EKX42001.1 - 0.014 14.9 2.7 0.2 11.3 0.1 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 EKX42001.1 - 0.02 14.2 0.4 3.4 6.9 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.17 EKX42001.1 - 0.023 14.8 3.3 3.4 7.7 0.4 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain SbcCD_C PF13558.6 EKX42001.1 - 0.068 13.4 0.1 20 5.5 0.0 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit IstB_IS21 PF01695.17 EKX42001.1 - 0.12 12.1 0.0 3.1 7.5 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 EKX42001.1 - 0.12 12.0 2.1 12 5.5 0.1 2.9 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 EKX42001.1 - 0.17 11.8 2.2 2 8.3 0.0 2.9 3 0 0 3 3 3 0 NACHT domain AAA_18 PF13238.6 EKX42001.1 - 0.34 11.5 1.5 36 4.9 0.2 3.3 3 1 0 3 3 2 0 AAA domain Sporozoite_P67 PF05642.11 EKX42001.1 - 2.5 6.1 11.8 3.7 5.5 11.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Roughex PF06020.11 EKX42001.1 - 8.8 5.3 6.7 15 4.5 6.7 1.3 1 0 0 1 1 1 0 Drosophila roughex protein BORCS7 PF16088.5 EKX42002.1 - 0.0083 16.4 1.5 0.0083 16.4 1.5 3.5 3 1 0 3 3 3 1 BLOC-1-related complex sub-unit 7 YqaH PF17448.2 EKX42002.1 - 0.2 11.9 3.8 0.12 12.7 0.8 2.2 2 0 0 2 2 2 0 Uncharacterized YqaH-like NPR2 PF06218.11 EKX42004.1 - 1e-25 90.4 0.5 2.7e-23 82.5 0.5 2.2 1 1 0 1 1 1 1 Nitrogen permease regulator 2 Ank_2 PF12796.7 EKX42006.1 - 1.7e-14 54.1 0.5 2.7e-14 53.5 0.5 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX42006.1 - 3.5e-14 53.0 0.7 9.2e-11 42.1 0.4 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX42006.1 - 2.3e-13 49.0 0.8 8.5e-05 22.7 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EKX42006.1 - 1.2e-11 44.6 2.6 5.6e-10 39.3 0.3 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX42006.1 - 3.8e-09 36.6 0.8 0.14 12.7 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat SET PF00856.28 EKX42007.1 - 8.9e-06 26.2 0.0 1.6e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 SET domain Thioredoxin_4 PF13462.6 EKX42007.1 - 0.044 13.9 0.1 0.16 12.1 0.1 1.9 1 0 0 1 1 1 0 Thioredoxin MRP-L20 PF12824.7 EKX42011.1 - 0.0091 16.2 0.4 0.013 15.7 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 CENP-B_N PF04218.13 EKX42011.1 - 0.063 12.9 0.1 0.15 11.7 0.1 1.7 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain IBN_N PF03810.19 EKX42012.1 - 4.2e-15 55.4 0.0 2.6e-14 52.9 0.0 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 EKX42012.1 - 2.9e-07 29.6 0.0 1e-06 27.9 0.1 1.9 2 0 0 2 2 2 1 Cse1 HEAT_2 PF13646.6 EKX42012.1 - 0.0032 17.8 1.2 2.9 8.4 0.0 4.4 4 0 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 EKX42012.1 - 0.0048 17.4 2.8 7.1 7.3 0.1 5.1 5 1 1 6 6 6 2 HEAT-like repeat Arm PF00514.23 EKX42012.1 - 0.05 13.7 0.0 29 4.9 0.0 3.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EKX42012.1 - 0.17 12.3 5.4 3.9 8.0 0.1 4.9 4 0 0 4 4 4 0 HEAT repeat VRR_NUC PF08774.11 EKX42013.1 - 4e-09 36.5 0.0 6.8e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 VRR-NUC domain MMACHC PF16690.5 EKX42016.1 - 0.00042 20.0 0.0 0.03 14.0 0.0 2.2 2 0 0 2 2 2 2 Methylmalonic aciduria and homocystinuria type C family PaaX_C PF08223.11 EKX42018.1 - 0.1 12.9 0.1 0.11 12.8 0.1 1.0 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain TPR_8 PF13181.6 EKX42019.1 - 2.9e-11 42.6 0.1 2.9e-06 27.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX42019.1 - 7.6e-09 35.0 0.3 2.8e-05 23.7 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX42019.1 - 3.5e-08 32.9 0.1 0.00072 19.5 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX42019.1 - 2.3e-07 31.1 0.3 0.064 14.1 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX42019.1 - 9e-07 29.3 0.1 0.0027 18.2 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX42019.1 - 1e-05 25.9 0.1 0.017 15.7 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX42019.1 - 2.4e-05 24.1 0.0 0.018 15.0 0.0 3.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX42019.1 - 0.0039 17.5 0.2 0.91 9.9 0.0 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX42019.1 - 0.0078 16.3 0.0 0.24 11.6 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX42019.1 - 0.0093 15.6 0.0 0.46 10.2 0.0 2.6 2 1 1 3 3 3 1 TPR repeat TPR_16 PF13432.6 EKX42019.1 - 0.021 15.5 0.2 5.1 7.8 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC5 PF12862.7 EKX42019.1 - 0.04 14.0 0.0 0.091 12.8 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 TPR_17 PF13431.6 EKX42019.1 - 0.13 12.7 1.1 6.6 7.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Claudin_2 PF13903.6 EKX42020.1 - 0.39 10.4 5.4 0.46 10.2 5.4 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Pox_A14 PF05767.12 EKX42020.1 - 0.97 9.6 6.2 1.9 8.7 6.2 1.6 1 1 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF3336 PF11815.8 EKX42021.1 - 1.1e-33 115.9 0.8 2.2e-33 114.9 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EKX42021.1 - 7.8e-14 52.3 0.0 1.7e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3446 PF11928.8 EKX42022.1 - 0.55 10.6 4.5 7.4 6.9 0.3 2.8 2 0 0 2 2 2 0 Early growth response N-terminal domain DOG1 PF14144.6 EKX42023.1 - 0.13 12.5 0.0 0.35 11.1 0.0 1.8 1 0 0 1 1 1 0 Seed dormancy control DUF4586 PF15239.6 EKX42024.1 - 1e-27 98.1 18.3 8.4e-22 78.7 2.9 3.1 1 1 2 3 3 3 3 Domain of unknown function (DUF4586) DUF4446 PF14584.6 EKX42025.1 - 0.0076 16.2 0.1 0.03 14.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4446) Tetraspanin PF00335.20 EKX42025.1 - 0.28 10.9 2.5 0.46 10.2 2.5 1.6 1 1 0 1 1 1 0 Tetraspanin family DUF4446 PF14584.6 EKX42026.1 - 0.0056 16.7 0.1 0.019 14.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4446) Tetraspanin PF00335.20 EKX42026.1 - 0.03 14.0 1.0 0.061 13.0 1.0 1.6 1 1 0 1 1 1 0 Tetraspanin family Bac_RepA_C PF18008.1 EKX42026.1 - 0.076 13.4 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Replication initiator protein A C-terminal domain UPF0184 PF03670.13 EKX42026.1 - 0.13 12.6 0.1 0.3 11.5 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) NrfD PF03916.14 EKX42027.1 - 0.04 13.5 1.1 0.067 12.8 1.1 1.3 1 0 0 1 1 1 0 Polysulphide reductase, NrfD EF-hand_7 PF13499.6 EKX42028.1 - 3.8e-13 49.7 6.1 3.2e-08 33.9 0.3 3.8 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX42028.1 - 7.5e-12 43.9 2.5 7.1e-05 22.1 0.3 3.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EKX42028.1 - 2e-10 39.7 2.3 2e-05 24.1 0.2 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 EKX42028.1 - 3.3e-09 35.8 4.8 3e-05 23.3 0.7 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX42028.1 - 0.00057 19.7 1.0 0.78 9.6 0.1 2.9 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX42028.1 - 0.0024 18.2 3.6 0.6 10.4 0.2 3.4 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region HTH_1 PF00126.27 EKX42028.1 - 0.028 14.4 0.3 7 6.7 0.0 2.8 2 1 1 3 3 3 0 Bacterial regulatory helix-turn-helix protein, lysR family CCSMST1 PF15013.6 EKX42028.1 - 0.1 12.7 0.0 0.31 11.2 0.0 1.9 1 1 0 1 1 1 0 CCSMST1 family Secretin_N_2 PF07655.13 EKX42028.1 - 0.16 12.6 14.5 0.36 11.4 14.5 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain Zip PF02535.22 EKX42028.1 - 0.17 11.1 0.4 0.28 10.4 0.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Tir_receptor_C PF07489.11 EKX42028.1 - 1.3 8.9 9.0 2.7 7.9 9.0 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Orf78 PF06024.12 EKX42028.1 - 1.5 9.1 16.8 0.42 10.9 12.0 2.4 2 1 1 3 3 2 0 Orf78 (ac78) DUF4604 PF15377.6 EKX42028.1 - 1.6 9.2 6.1 11 6.4 0.1 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF4604) HCO3_cotransp PF00955.21 EKX42028.1 - 2.1 7.1 8.1 2.9 6.6 7.7 1.4 1 1 0 1 1 1 0 HCO3- transporter family TMEM154 PF15102.6 EKX42028.1 - 5 7.0 15.9 0.25 11.3 9.7 2.0 2 1 1 3 3 3 0 TMEM154 protein family Renin_r PF07850.14 EKX42028.1 - 7.8 7.2 8.4 1.4 9.5 4.0 2.1 2 1 0 2 2 1 0 Renin receptor-like protein Fer4_16 PF13484.6 EKX42029.1 - 3.4e-20 72.7 6.7 6.1e-20 71.9 6.7 1.4 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 EKX42029.1 - 2.9e-08 33.7 2.1 0.00032 20.8 1.0 2.4 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 EKX42029.1 - 2.1e-06 28.2 8.6 5.8e-06 26.8 8.7 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 EKX42029.1 - 0.00034 20.3 13.4 0.0038 17.0 2.7 2.8 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_6 PF12837.7 EKX42029.1 - 0.0066 16.5 2.1 0.0066 16.5 2.1 2.5 2 1 0 2 2 2 1 4Fe-4S binding domain Fer4_9 PF13187.6 EKX42029.1 - 0.0081 16.3 11.7 0.24 11.6 12.7 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 EKX42029.1 - 0.013 15.5 13.2 0.41 10.8 4.0 2.8 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_3 PF12798.7 EKX42029.1 - 0.019 15.9 14.4 0.56 11.3 5.5 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_21 PF14697.6 EKX42029.1 - 0.026 14.7 11.5 0.34 11.1 11.5 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 EKX42029.1 - 0.052 14.0 10.4 0.85 10.1 11.2 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain SCIFF PF13165.6 EKX42029.1 - 0.18 11.8 4.4 0.43 10.6 0.6 2.3 2 0 0 2 2 2 0 Six-cysteine peptide SCIFF Fer4_4 PF12800.7 EKX42029.1 - 0.46 11.1 8.9 5.7 7.7 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 EKX42029.1 - 0.86 10.2 9.5 3.1 8.4 9.6 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 EKX42029.1 - 1.4 9.1 8.3 2 8.7 1.6 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain TPR_8 PF13181.6 EKX42030.1 - 7.6e-20 69.4 16.1 0.012 15.8 0.2 10.3 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.6 EKX42030.1 - 1.9e-19 68.7 14.7 0.079 13.8 0.0 8.8 5 3 3 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 EKX42030.1 - 3.7e-19 67.2 17.4 0.016 15.3 0.0 8.6 10 0 0 10 10 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 EKX42030.1 - 4.1e-18 65.6 20.6 0.0017 18.8 1.3 7.5 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 EKX42030.1 - 3.2e-17 61.6 8.8 0.0011 19.2 0.0 7.3 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX42030.1 - 4.9e-17 61.0 15.9 0.0014 18.3 0.1 8.2 9 0 0 9 9 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 EKX42030.1 - 5.1e-17 62.2 7.0 0.00054 20.6 1.3 5.7 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 EKX42030.1 - 9e-14 50.9 14.4 0.0036 17.0 0.0 8.0 7 1 1 8 8 8 3 TPR repeat TPR_7 PF13176.6 EKX42030.1 - 1.5e-09 37.2 7.8 1.3 9.2 0.1 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX42030.1 - 2.3e-07 31.0 24.8 0.027 14.7 0.1 7.7 7 2 1 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX42030.1 - 3.2e-06 26.8 16.4 0.25 11.3 0.2 7.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX42030.1 - 0.00039 20.9 6.8 22 5.9 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TOM20_plant PF06552.12 EKX42030.1 - 0.003 17.3 4.3 8 6.2 0.0 4.9 3 1 2 5 5 5 0 Plant specific mitochondrial import receptor subunit TOM20 NARP1 PF12569.8 EKX42030.1 - 0.021 13.8 12.1 0.0087 15.0 2.7 3.7 4 0 0 4 4 4 0 NMDA receptor-regulated protein 1 THOC2_N PF16134.5 EKX42030.1 - 0.032 12.9 2.3 0.059 12.0 2.3 1.3 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus TPR_9 PF13371.6 EKX42030.1 - 0.089 13.0 13.2 5.9 7.1 0.4 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat RNA_polI_A34 PF08208.11 EKX42030.1 - 0.1 12.7 15.0 0.18 11.8 15.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 PPR PF01535.20 EKX42030.1 - 0.16 12.3 4.8 2.1 8.8 0.0 4.4 4 0 0 4 4 3 0 PPR repeat FancD2 PF14631.6 EKX42030.1 - 0.17 9.3 6.0 0.24 8.8 6.0 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DUF913 PF06025.12 EKX42030.1 - 0.24 10.3 2.3 0.41 9.6 2.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) ANAPC3 PF12895.7 EKX42030.1 - 0.25 11.6 6.5 13 6.0 0.0 4.3 4 2 0 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Wzy_C_2 PF11846.8 EKX42030.1 - 0.28 11.1 3.5 9.8 6.0 0.0 2.9 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal CDC45 PF02724.14 EKX42030.1 - 0.35 9.1 7.7 0.62 8.3 7.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.8 EKX42030.1 - 0.4 9.4 8.8 0.029 13.2 3.6 1.7 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Ferlin_C PF16165.5 EKX42030.1 - 0.44 10.5 11.9 0.95 9.4 11.9 1.5 1 0 0 1 1 1 0 Ferlin C-terminus CPSF100_C PF13299.6 EKX42030.1 - 0.48 10.6 8.1 1.2 9.3 8.1 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RNA_pol_Rpc4 PF05132.14 EKX42030.1 - 0.53 10.7 5.5 1.5 9.3 5.5 1.7 1 0 0 1 1 1 0 RNA polymerase III RPC4 RPA43_OB PF17875.1 EKX42030.1 - 0.67 10.6 4.8 1.9 9.1 4.8 1.8 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I NPR3 PF03666.13 EKX42030.1 - 0.69 8.6 12.6 4.1 6.1 7.1 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Peptidase_S49_N PF08496.10 EKX42030.1 - 0.79 9.8 6.7 1.8 8.6 6.7 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FHIPEP PF00771.20 EKX42030.1 - 0.9 7.9 4.4 1.4 7.3 4.4 1.2 1 0 0 1 1 1 0 FHIPEP family LUC7 PF03194.15 EKX42030.1 - 1.9 8.1 14.8 1.4 8.6 12.3 2.0 2 0 0 2 2 2 0 LUC7 N_terminus MAS20 PF02064.15 EKX42030.1 - 3.3 7.8 16.3 0.69 10.0 6.9 3.5 2 1 1 3 3 3 0 MAS20 protein import receptor FAM176 PF14851.6 EKX42030.1 - 5.2 6.7 15.4 0.56 9.9 10.4 2.0 2 0 0 2 2 1 0 FAM176 family EIIBC-GUT_N PF03612.14 EKX42030.1 - 5.9 6.6 8.1 13 5.5 8.1 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Cytomega_UL84 PF06284.11 EKX42030.1 - 7.9 4.8 8.3 14 4.0 8.3 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Connexin PF00029.19 EKX42030.1 - 9.5 5.9 8.2 20 4.9 8.2 1.5 1 0 0 1 1 1 0 Connexin PTE PF02126.18 EKX42031.1 - 1.4e-44 152.8 0.0 1.5e-44 152.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotriesterase family VATC PF18716.1 EKX42031.1 - 3.1e-11 42.9 4.0 3.1e-11 42.9 4.0 1.9 2 0 0 2 2 2 1 Vms1-associating treble clef domain Haem_degrading PF03928.14 EKX42031.1 - 0.1 12.7 0.2 0.18 11.8 0.2 1.5 1 0 0 1 1 1 0 Haem-degrading zf-MYND PF01753.18 EKX42031.1 - 3.7 7.7 8.6 0.19 11.9 2.7 1.9 2 1 0 2 2 2 0 MYND finger PARG_cat PF05028.14 EKX42032.1 - 1.1e-76 258.3 0.1 8.3e-75 252.2 0.1 2.0 1 1 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) AKAP_110 PF05716.13 EKX42032.1 - 0.0083 14.4 0.0 0.012 13.9 0.0 1.1 1 0 0 1 1 1 1 A-kinase anchor protein 110 kDa (AKAP 110) TRAF_BIRC3_bd PF16673.5 EKX42034.1 - 0.075 12.8 0.4 0.075 12.8 0.4 5.0 4 1 1 5 5 5 0 TNF receptor-associated factor BIRC3 binding domain Rubredoxin PF00301.20 EKX42036.1 - 0.00014 21.8 4.2 0.0061 16.6 4.2 2.3 1 1 0 1 1 1 1 Rubredoxin RNA_POL_M_15KD PF02150.16 EKX42036.1 - 0.042 13.7 0.0 2.1 8.3 0.0 2.3 1 1 1 2 2 2 0 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 EKX42036.1 - 0.23 11.4 1.0 1.2 9.2 0.1 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Mpv17_PMP22 PF04117.12 EKX42037.1 - 2.4e-08 34.1 0.2 5.4e-08 32.9 0.2 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family SNF PF00209.18 EKX42039.1 - 1.3e-75 255.1 20.5 1.5e-73 248.3 14.1 2.2 2 0 0 2 2 2 2 Sodium:neurotransmitter symporter family PseudoU_synth_2 PF00849.22 EKX42041.1 - 1.7e-24 86.7 0.0 3.3e-24 85.8 0.0 1.5 1 1 0 1 1 1 1 RNA pseudouridylate synthase Zn_clus PF00172.18 EKX42042.1 - 6e-11 42.3 24.5 2.6e-06 27.4 11.1 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 EKX42043.1 - 5.1e-11 42.5 24.3 3.1e-06 27.2 10.9 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Complex1_LYR PF05347.15 EKX42044.1 - 0.00026 21.0 0.2 0.0004 20.4 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EKX42044.1 - 0.082 13.7 0.1 0.11 13.3 0.1 1.3 1 1 0 1 1 1 0 Complex1_LYR-like Glyco_transf_7N PF13733.6 EKX42048.1 - 9.7e-13 47.9 0.0 1.7e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 UDPG_MGDP_dh_N PF03721.14 EKX42049.1 - 5.1e-26 91.4 0.1 6.6e-26 91.0 0.1 1.1 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 EKX42049.1 - 1.3e-24 86.2 0.0 2.8e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_Gly3P_dh_N PF01210.23 EKX42049.1 - 0.0013 18.7 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 EKX42049.1 - 0.0078 15.9 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 EKX42049.1 - 0.031 14.5 0.0 0.082 13.1 0.0 1.8 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DEAD PF00270.29 EKX42052.1 - 2.5e-42 144.6 0.2 4.3e-42 143.8 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EKX42052.1 - 1.7e-07 31.4 2.4 6e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EKX42052.1 - 0.013 15.7 0.4 0.088 13.1 0.2 2.3 1 1 1 2 2 2 0 AAA domain Macoilin PF09726.9 EKX42052.1 - 0.045 12.3 3.3 0.055 12.0 3.3 1.1 1 0 0 1 1 1 0 Macoilin family PNISR PF15996.5 EKX42052.1 - 0.13 12.5 21.2 0.23 11.7 21.2 1.4 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR SAM_2 PF07647.17 EKX42053.1 - 4.3e-06 26.7 0.1 9.1e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EKX42053.1 - 1e-05 25.9 0.7 5.8e-05 23.4 0.7 2.0 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) Dynein_light PF01221.18 EKX42054.1 - 1.2e-11 44.8 0.2 2.8e-09 37.2 0.0 3.5 3 0 0 3 3 3 2 Dynein light chain type 1 Ank_5 PF13857.6 EKX42055.1 - 3e-12 46.5 0.0 3.4e-07 30.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX42055.1 - 2.9e-09 37.4 0.0 0.00027 21.5 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX42055.1 - 3.8e-09 36.9 0.0 0.0018 18.8 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX42055.1 - 4.4e-09 36.4 0.1 0.0028 18.0 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EKX42055.1 - 5.7e-08 32.4 0.0 0.059 14.0 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat DUF4834 PF16118.5 EKX42055.1 - 5.6e-05 24.0 0.2 0.18 12.8 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4834) FAM176 PF14851.6 EKX42055.1 - 0.0001 22.0 2.1 0.43 10.2 3.4 2.2 2 0 0 2 2 2 2 FAM176 family TRAP_alpha PF03896.16 EKX42055.1 - 0.0017 17.6 3.1 0.96 8.6 3.2 2.1 2 0 0 2 2 2 2 Translocon-associated protein (TRAP), alpha subunit Tim54 PF11711.8 EKX42055.1 - 0.0039 16.0 0.2 0.0039 16.0 0.2 1.4 2 0 0 2 2 2 1 Inner membrane protein import complex subunit Tim54 Tmemb_9 PF05434.11 EKX42055.1 - 0.007 16.3 0.6 0.3 11.0 0.0 2.1 2 0 0 2 2 2 1 TMEM9 Myc_N PF01056.18 EKX42055.1 - 0.0074 16.2 3.4 0.0097 15.8 3.4 1.2 1 0 0 1 1 1 1 Myc amino-terminal region V_ATPase_I PF01496.19 EKX42055.1 - 0.013 13.5 0.2 2.6 5.9 0.0 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CDC45 PF02724.14 EKX42055.1 - 0.02 13.2 0.2 0.02 13.2 0.2 1.9 2 0 0 2 2 2 0 CDC45-like protein HemY_N PF07219.13 EKX42055.1 - 0.026 14.7 0.0 0.055 13.7 0.0 1.5 1 0 0 1 1 1 0 HemY protein N-terminus G0-G1_switch_2 PF15103.6 EKX42055.1 - 0.026 15.0 0.3 0.12 12.8 0.7 1.8 3 0 0 3 3 1 0 G0/G1 switch protein 2 RAB3GAP2_C PF14656.6 EKX42055.1 - 0.052 11.8 0.8 0.071 11.3 0.8 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Ureide_permease PF07168.11 EKX42055.1 - 0.24 10.1 0.0 0.32 9.7 0.0 1.1 1 0 0 1 1 1 0 Ureide permease Porph_ging PF09697.10 EKX42055.1 - 0.26 11.9 2.4 0.28 11.8 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (Porph_ging) PI3K_1B_p101 PF10486.9 EKX42055.1 - 0.38 8.5 1.6 0.59 7.9 1.6 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CENP-B_dimeris PF09026.10 EKX42055.1 - 0.49 10.8 13.1 0.2 12.0 4.5 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RXT2_N PF08595.11 EKX42055.1 - 0.7 9.9 7.7 0.82 9.7 1.1 2.1 2 0 0 2 2 2 0 RXT2-like, N-terminal AIM3 PF17096.5 EKX42055.1 - 1 10.4 3.7 1.1 10.3 0.1 2.1 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 RPN2_C PF18004.1 EKX42055.1 - 1.7 8.5 8.8 2.5 8.0 5.5 2.0 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4719 PF15843.5 EKX42055.1 - 1.8 8.6 0.0 1.8 8.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) DUF4611 PF15387.6 EKX42055.1 - 2.2 8.5 12.4 2 8.7 5.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Usp PF00582.26 EKX42055.1 - 4 7.9 5.6 9 6.8 5.6 1.5 1 0 0 1 1 1 0 Universal stress protein family RPA43_OB PF17875.1 EKX42055.1 - 6.9 7.3 7.1 0.97 10.1 1.1 2.0 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Beta_helix PF13229.6 EKX42056.1 - 1.1e-06 28.6 0.0 1.7e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Right handed beta helix region CDC45 PF02724.14 EKX42057.1 - 3.1 6.0 7.2 4.9 5.3 7.2 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF3801 PF12687.7 EKX42057.1 - 4.2 7.4 10.9 1.4 8.9 8.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) Ribosomal_L15e PF00827.17 EKX42058.1 - 7.9e-88 293.2 6.3 9e-88 293.0 6.3 1.0 1 0 0 1 1 1 1 Ribosomal L15 DnaJ_C PF01556.18 EKX42059.1 - 7.4e-30 104.0 0.0 1.4e-29 103.1 0.0 1.5 1 0 0 1 1 1 1 DnaJ C terminal domain LMBR1 PF04791.16 EKX42059.1 - 0.48 9.3 0.7 0.65 8.8 0.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CCDC-167 PF15188.6 EKX42059.1 - 0.67 10.3 4.1 33 4.9 0.0 3.3 2 1 0 3 3 3 0 Coiled-coil domain-containing protein 167 DUF4164 PF13747.6 EKX42059.1 - 0.71 10.2 3.8 0.39 11.0 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) RCC1 PF00415.18 EKX42060.1 - 6.2e-52 174.0 11.0 6e-13 49.2 0.2 5.1 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX42060.1 - 1.7e-29 101.0 23.2 1e-07 31.6 0.3 5.5 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat C2 PF00168.30 EKX42061.1 - 0.00011 22.4 0.0 0.0002 21.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain Lig_chan PF00060.26 EKX42062.1 - 6.5e-08 32.6 0.0 1.1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Ligand-gated ion channel SBP_bac_3 PF00497.20 EKX42062.1 - 1.5e-05 24.5 0.0 3.9e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 EKX42062.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Ligated ion channel L-glutamate- and glycine-binding site Tail_VII PF17091.5 EKX42062.1 - 0.26 11.2 1.2 0.56 10.1 0.1 2.1 2 0 0 2 2 2 0 Inovirus G7P protein TPR_2 PF07719.17 EKX42064.1 - 0.014 15.5 0.5 0.014 15.5 0.5 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF737 PF05300.11 EKX42064.1 - 0.02 15.3 8.5 0.2 12.0 5.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF737) TPR_16 PF13432.6 EKX42064.1 - 0.031 14.9 0.8 0.099 13.3 0.8 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Mito_carr PF00153.27 EKX42065.1 - 8e-51 169.9 0.0 3.5e-19 68.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Asp PF00026.23 EKX42066.1 - 4.8e-19 68.9 0.0 5.1e-11 42.6 0.0 2.9 3 0 0 3 3 3 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EKX42066.1 - 1.9e-05 25.0 0.1 0.0018 18.5 0.0 3.1 2 1 1 3 3 3 1 Xylanase inhibitor N-terminal CD34_antigen PF06365.12 EKX42066.1 - 0.13 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family TTL PF03133.15 EKX42067.1 - 1.9e-76 257.0 0.1 2.6e-75 253.3 0.1 2.0 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EKX42067.1 - 2.4e-05 23.7 0.0 0.0002 20.7 0.0 2.1 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EKX42067.1 - 8.2e-05 22.0 0.0 0.0016 17.8 0.0 2.2 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp GDE_C PF06202.14 EKX42067.1 - 0.024 13.6 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Dus PF01207.17 EKX42067.1 - 0.21 10.6 0.1 0.31 10.1 0.1 1.2 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Casc1 PF12366.8 EKX42068.1 - 0.51 9.8 2.7 0.77 9.2 2.7 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 SelR PF01641.18 EKX42070.1 - 6.8e-43 145.6 0.1 7.5e-43 145.5 0.1 1.0 1 0 0 1 1 1 1 SelR domain DZR PF12773.7 EKX42070.1 - 0.0098 15.9 0.1 0.03 14.3 0.0 1.8 2 1 0 2 2 2 1 Double zinc ribbon TF_Zn_Ribbon PF08271.12 EKX42070.1 - 0.021 14.4 0.6 4.5 6.9 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding HypA PF01155.19 EKX42070.1 - 0.066 13.2 0.3 0.12 12.4 0.3 1.4 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA HECT_2 PF09814.9 EKX42070.1 - 0.14 11.0 0.2 2.7 6.7 0.0 2.0 2 0 0 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Auto_anti-p27 PF06677.12 EKX42070.1 - 0.16 12.1 3.2 3.9 7.7 0.1 2.8 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-ribbon_3 PF13248.6 EKX42070.1 - 0.2 11.1 4.9 4 7.0 0.9 2.3 2 0 0 2 2 2 0 zinc-ribbon domain WD40 PF00400.32 EKX42071.1 - 3.9e-29 100.3 12.4 9.4e-09 35.8 0.4 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX42071.1 - 1.1e-16 60.9 0.7 3.9e-07 30.3 0.1 3.9 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EKX42071.1 - 2.7e-06 26.3 0.1 0.0015 17.2 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 WD40_like PF17005.5 EKX42071.1 - 7.2e-05 22.3 0.0 0.7 9.2 0.0 3.2 2 1 0 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 EKX42071.1 - 0.00017 20.7 0.1 0.35 9.8 0.1 2.7 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EKX42071.1 - 0.00024 21.0 0.2 0.051 13.4 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.9 EKX42071.1 - 0.021 14.6 0.4 2.1 8.0 0.1 2.9 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain Glyoxal_oxid_N PF07250.11 EKX42071.1 - 0.11 11.6 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus PDZ PF00595.24 EKX42072.1 - 0.00035 20.9 0.0 0.00088 19.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX42072.1 - 0.0004 20.7 0.0 0.00097 19.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain BSP_II PF05432.11 EKX42072.1 - 0.00044 20.1 19.7 0.00044 20.1 19.7 2.0 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) Nop14 PF04147.12 EKX42072.1 - 0.0045 15.3 11.7 0.0064 14.8 11.7 1.2 1 0 0 1 1 1 1 Nop14-like family RR_TM4-6 PF06459.12 EKX42072.1 - 0.021 14.6 8.7 0.044 13.6 8.7 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 EKX42072.1 - 0.041 12.2 14.2 0.071 11.4 14.2 1.3 1 0 0 1 1 1 0 CDC45-like protein CPSF100_C PF13299.6 EKX42072.1 - 0.13 12.5 5.7 0.32 11.2 5.7 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4604 PF15377.6 EKX42072.1 - 0.18 12.2 15.1 0.034 14.6 10.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) DUF2052 PF09747.9 EKX42072.1 - 0.45 10.6 25.3 0.024 14.8 18.9 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SET PF00856.28 EKX42072.1 - 0.46 10.8 2.5 1.5 9.2 1.9 2.2 2 1 0 2 2 2 0 SET domain CobT PF06213.12 EKX42072.1 - 1.7 7.9 25.3 3.9 6.8 25.3 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mpp10 PF04006.12 EKX42072.1 - 2.3 6.6 23.4 3.9 5.8 23.4 1.3 1 0 0 1 1 1 0 Mpp10 protein PTPRCAP PF15713.5 EKX42072.1 - 3.6 7.9 25.8 0.73 10.1 19.6 2.8 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DUF913 PF06025.12 EKX42072.1 - 4.6 6.1 5.1 9 5.2 5.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Pox_Ag35 PF03286.14 EKX42072.1 - 5.2 6.8 14.3 13 5.5 14.3 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sec62 PF03839.16 EKX42072.1 - 5.4 6.5 4.9 10 5.6 4.9 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Plasmodium_Vir PF05795.11 EKX42072.1 - 7.3 5.9 7.7 13 5.1 7.7 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Presenilin PF01080.17 EKX42072.1 - 8 5.1 10.3 13 4.4 10.3 1.2 1 0 0 1 1 1 0 Presenilin PARP PF00644.20 EKX42074.1 - 6.5e-16 58.5 0.7 2.2e-15 56.7 0.0 2.0 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 EKX42074.1 - 3.4e-09 37.2 0.4 9.7e-09 35.7 0.4 1.8 1 0 0 1 1 1 1 WWE domain TraQ PF09679.10 EKX42074.1 - 0.073 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) Chalcone_2 PF16035.5 EKX42075.1 - 4.8e-13 49.4 0.0 1.9e-09 37.6 0.0 2.3 1 1 1 2 2 2 2 Chalcone isomerase like Chalcone_3 PF16036.5 EKX42075.1 - 4.6e-10 39.9 0.0 7.6e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Chalcone isomerase-like Chalcone PF02431.15 EKX42075.1 - 0.0072 15.7 0.0 0.087 12.2 0.0 2.0 2 0 0 2 2 2 1 Chalcone-flavanone isomerase GST_N_3 PF13417.6 EKX42077.1 - 1.1e-33 115.5 0.5 7.4e-16 58.3 0.0 2.7 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EKX42077.1 - 6e-18 64.9 0.0 7.5e-09 35.8 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EKX42077.1 - 8e-12 45.3 0.0 3.2e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 EKX42077.1 - 4.2e-10 39.7 1.1 0.00012 22.2 0.0 2.7 3 0 0 3 3 3 2 Glutaredoxin GST_N_4 PF17172.4 EKX42077.1 - 0.078 13.7 0.0 9.7 7.0 0.0 2.6 2 1 0 2 2 2 0 Glutathione S-transferase N-terminal domain Peptidase_MA_2 PF13485.6 EKX42077.1 - 0.13 11.9 0.0 3.2 7.3 0.0 2.0 2 0 0 2 2 2 0 Peptidase MA superfamily Zn_clus PF00172.18 EKX42078.1 - 5.9e-13 48.7 34.5 2.9e-06 27.3 10.7 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_binding_1 PF01035.20 EKX42078.1 - 0.094 12.9 2.3 5.4 7.2 0.3 2.3 1 1 1 2 2 2 0 6-O-methylguanine DNA methyltransferase, DNA binding domain Kelch_1 PF01344.25 EKX42079.1 - 2.5e-44 148.6 0.2 8.6e-11 41.2 0.0 5.1 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 EKX42079.1 - 4.1e-21 74.5 0.5 4.4e-05 23.6 0.0 5.2 2 2 3 5 5 5 5 Kelch motif Kelch_2 PF07646.15 EKX42079.1 - 7.3e-13 47.9 2.7 0.00056 19.8 0.0 4.4 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 EKX42079.1 - 1.3e-06 28.2 4.9 0.02 14.9 0.0 4.4 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 EKX42079.1 - 8.9e-06 25.6 0.7 0.6 10.2 0.0 4.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 EKX42079.1 - 0.00027 21.1 2.7 2.1 8.8 0.0 4.4 4 1 0 4 4 4 2 Galactose oxidase, central domain Ank_2 PF12796.7 EKX42080.1 - 4.2e-09 36.9 0.4 2.1e-07 31.4 0.2 3.2 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) UvrD_C_2 PF13538.6 EKX42080.1 - 1.8e-07 30.8 0.3 0.019 14.8 0.0 3.0 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain Ank_4 PF13637.6 EKX42080.1 - 2.6e-07 31.0 0.1 2.4e-05 24.8 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) UvrD-helicase PF00580.21 EKX42080.1 - 2.7e-07 30.4 0.0 2.7e-07 30.4 0.0 5.1 5 0 0 5 5 5 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 EKX42080.1 - 5.9e-05 22.6 0.0 0.00077 18.9 0.0 3.1 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EKX42080.1 - 6.5e-05 23.3 0.0 0.0005 20.4 0.0 2.5 1 1 0 1 1 1 1 AAA domain Ank PF00023.30 EKX42080.1 - 0.00011 22.5 0.9 6.7 7.3 0.0 4.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EKX42080.1 - 0.0018 18.5 0.1 1 9.8 0.1 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) ResIII PF04851.15 EKX42080.1 - 0.0023 17.9 0.4 0.018 15.1 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EKX42080.1 - 0.0053 16.5 0.0 1.6 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Ank_3 PF13606.6 EKX42080.1 - 0.016 15.7 1.5 3.7 8.4 0.2 4.1 4 0 0 4 4 3 0 Ankyrin repeat AAA_22 PF13401.6 EKX42080.1 - 0.049 13.9 0.2 23 5.3 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 EKX42080.1 - 0.059 13.8 0.3 0.91 9.9 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain PhoH PF02562.16 EKX42080.1 - 0.081 12.4 0.0 11 5.4 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.6 EKX42080.1 - 0.084 12.4 0.0 0.37 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain TssD PF17642.1 EKX42081.1 - 0.0094 15.8 0.1 0.12 12.2 0.0 2.7 2 2 1 4 4 4 1 Hemolysin coregulated protein Hcp (TssD) PAS PF00989.25 EKX42082.1 - 0.13 12.3 0.0 0.46 10.5 0.0 2.0 2 1 1 3 3 3 0 PAS fold DSHCT PF08148.12 EKX42083.1 - 0.18 11.4 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 DSHCT (NUC185) domain NOG1 PF06858.14 EKX42084.1 - 2.3e-17 62.5 0.0 5e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 EKX42084.1 - 6.5e-17 61.7 0.1 1.5e-16 60.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase NOG1_N PF17835.1 EKX42084.1 - 3.1e-11 43.5 0.1 4.8e-11 42.9 0.1 1.3 1 0 0 1 1 1 1 NOG1 N-terminal helical domain FeoB_N PF02421.18 EKX42084.1 - 3.5e-07 29.9 0.0 6.1e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF810 PF05664.11 EKX42084.1 - 0.0082 14.7 0.1 0.011 14.3 0.1 1.1 1 0 0 1 1 1 1 Plant family of unknown function (DUF810) AIG1 PF04548.16 EKX42084.1 - 0.018 14.3 0.1 0.041 13.2 0.1 1.5 1 1 0 1 1 1 0 AIG1 family NB-ARC PF00931.22 EKX42084.1 - 0.03 13.5 0.1 2.8 7.1 0.0 2.6 2 1 1 3 3 3 0 NB-ARC domain AAA_16 PF13191.6 EKX42084.1 - 0.036 14.4 0.0 0.11 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 EKX42084.1 - 0.049 13.9 0.1 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EKX42084.1 - 0.05 13.7 1.4 9.3 6.3 0.0 2.8 3 0 0 3 3 3 0 Dynamin family RsgA_GTPase PF03193.16 EKX42084.1 - 0.053 13.4 1.3 0.49 10.3 0.2 2.6 1 1 1 2 2 2 0 RsgA GTPase KTI12 PF08433.10 EKX42084.1 - 0.22 10.9 0.7 16 4.8 0.1 2.3 2 1 0 2 2 2 0 Chromatin associated protein KTI12 Ank_2 PF12796.7 EKX42085.1 - 2.6e-08 34.3 0.0 8.8e-08 32.6 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX42085.1 - 2.2e-07 31.0 0.1 0.0048 17.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX42085.1 - 4.1e-07 30.4 0.0 8.4e-06 26.2 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX42085.1 - 2.2e-06 27.6 0.0 0.034 14.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EKX42085.1 - 1.6e-05 25.1 0.0 0.038 14.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Hamartin PF04388.12 EKX42085.1 - 0.027 13.2 14.0 0.046 12.4 14.0 1.3 1 0 0 1 1 1 0 Hamartin protein CDC27 PF09507.10 EKX42085.1 - 0.37 10.1 39.9 0.0079 15.6 32.2 1.8 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 SAPS PF04499.15 EKX42086.1 - 5.4 5.7 10.8 7.1 5.3 10.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MCLC PF05934.11 EKX42086.1 - 5.8 5.5 8.6 7.5 5.2 8.6 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Zip PF02535.22 EKX42086.1 - 6.2 5.9 9.4 31 3.7 7.6 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Ribosomal_L26 PF16906.5 EKX42087.1 - 5.1 7.6 6.3 14 6.2 6.3 1.9 1 1 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal SIS PF01380.22 EKX42088.1 - 2e-24 85.9 0.2 2.9e-24 85.4 0.2 1.2 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.6 EKX42088.1 - 5.6e-06 26.4 1.8 0.00014 21.9 0.0 2.5 1 1 1 2 2 2 1 SIS domain DUF2529 PF10740.9 EKX42088.1 - 0.0015 18.2 0.1 0.0036 16.9 0.0 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF2529) DUF1623 PF07785.11 EKX42088.1 - 0.16 12.1 0.0 0.99 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1623) KH_1 PF00013.29 EKX42089.1 - 7.3e-38 128.2 4.3 5e-12 45.5 0.1 3.1 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EKX42089.1 - 1.1e-08 34.8 1.6 0.0027 17.5 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EKX42089.1 - 7.3e-08 32.1 1.9 0.14 12.0 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EKX42089.1 - 0.036 14.2 4.7 5.8 7.1 0.1 3.7 3 1 1 4 4 4 0 NusA-like KH domain DUF2828 PF11443.8 EKX42091.1 - 1.1e-28 99.8 0.1 1.1e-28 99.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) VWA_CoxE PF05762.14 EKX42091.1 - 6.6e-07 28.9 0.0 8.8e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF2828 PF11443.8 EKX42092.1 - 2.4e-33 115.2 0.0 5.8e-28 97.4 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF2828) DUF4777 PF16007.5 EKX42092.1 - 0.11 12.7 0.1 0.32 11.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) DUF2856 PF11043.8 EKX42093.1 - 0.031 14.4 0.4 0.26 11.4 0.4 2.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2856) DUF4287 PF14117.6 EKX42093.1 - 0.38 10.9 2.8 11 6.2 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4287) DEAD PF00270.29 EKX42094.1 - 1.2e-20 74.0 0.0 5.3e-20 71.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX42094.1 - 2.2e-17 63.4 0.0 9.4e-17 61.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EKX42094.1 - 1.5e-14 54.4 5.8 1.5e-14 54.4 5.8 2.1 2 0 0 2 2 2 1 RecQ zinc-binding ResIII PF04851.15 EKX42094.1 - 6.4e-06 26.3 0.0 7e-05 22.9 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EKX42094.1 - 0.048 12.4 0.0 0.074 11.8 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.6 EKX42094.1 - 0.16 12.2 0.0 0.65 10.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain B9-C2 PF07162.11 EKX42095.1 - 5.4e-35 121.1 0.1 7.2e-35 120.7 0.1 1.2 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein RWP-RK PF02042.15 EKX42096.1 - 4.8e-10 39.3 0.0 6.9e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain Lycopene_cycl PF05834.12 EKX42097.1 - 6e-90 302.0 0.0 7.2e-90 301.8 0.0 1.0 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EKX42097.1 - 2.1e-08 33.8 0.3 5.9e-05 22.4 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EKX42097.1 - 4.6e-05 22.8 0.6 0.00021 20.7 0.4 2.0 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 EKX42097.1 - 5.7e-05 22.2 0.5 0.00053 19.0 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.17 EKX42097.1 - 6.1e-05 22.4 0.1 0.0083 15.4 0.1 2.2 2 0 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.24 EKX42097.1 - 0.0015 17.7 0.1 0.0023 17.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EKX42097.1 - 0.0015 17.3 0.1 0.031 13.0 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 EKX42097.1 - 0.0059 15.7 0.0 2.1 7.4 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EKX42097.1 - 0.0097 16.1 0.0 0.025 14.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EKX42097.1 - 0.019 15.0 0.1 8.3 6.4 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.24 EKX42097.1 - 0.031 13.9 0.1 6.6 6.2 0.1 2.5 2 1 0 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EKX42097.1 - 0.072 12.4 0.2 3.1 7.1 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase SPATA24 PF15175.6 EKX42098.1 - 0.039 13.8 4.9 0.052 13.4 4.9 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 CAP_N PF01213.19 EKX42098.1 - 0.087 12.3 1.6 0.12 11.8 1.6 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal FUSC PF04632.12 EKX42098.1 - 0.095 11.2 5.6 0.1 11.1 5.6 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Atg14 PF10186.9 EKX42098.1 - 0.13 11.3 8.2 0.17 11.0 8.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_TATA_bd PF12325.8 EKX42098.1 - 0.17 12.1 4.9 0.32 11.2 4.9 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 EKX42098.1 - 0.34 10.9 3.7 0.81 9.7 3.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Ank_4 PF13637.6 EKX42099.1 - 2.5e-21 75.8 0.5 5.8e-12 45.9 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX42099.1 - 1.8e-19 69.6 3.5 3.8e-10 39.8 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX42099.1 - 3e-18 66.2 0.4 6.5e-18 65.1 0.4 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX42099.1 - 5.9e-17 60.0 0.1 1.1e-05 25.5 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 EKX42099.1 - 1.8e-16 59.7 0.6 1.1e-07 31.9 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat PDZ_6 PF17820.1 EKX42100.1 - 1.5e-06 27.9 0.0 2.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX42100.1 - 0.00013 22.2 0.0 0.00017 21.8 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX42100.1 - 0.0091 16.3 0.0 0.017 15.4 0.0 1.6 2 0 0 2 2 2 1 PDZ domain DNA_pol_A_exo1 PF01612.20 EKX42101.1 - 1.8e-13 50.6 0.1 4.1e-12 46.2 0.1 2.2 1 1 0 1 1 1 1 3'-5' exonuclease Cauli_VI PF01693.16 EKX42101.1 - 0.0054 17.0 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin PBP1_TM PF14812.6 EKX42102.1 - 5.7 7.4 15.3 0.83 10.1 6.0 3.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Methyltransf_16 PF10294.9 EKX42104.1 - 2e-13 50.4 0.2 2.6e-12 46.8 0.2 2.1 1 1 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EKX42104.1 - 0.012 15.1 0.0 0.021 14.4 0.0 1.4 2 0 0 2 2 2 0 Methyltransferase small domain MCM PF00493.23 EKX42107.1 - 9.6e-103 342.1 0.2 1.3e-102 341.6 0.2 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EKX42107.1 - 6.1e-41 139.2 0.6 1.1e-40 138.3 0.6 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EKX42107.1 - 2.2e-27 95.3 3.0 4.4e-27 94.3 3.0 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EKX42107.1 - 5.1e-07 29.3 0.0 2.9e-06 26.8 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EKX42107.1 - 0.00011 22.2 0.0 0.00027 20.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EKX42107.1 - 0.00074 19.4 0.0 0.002 18.0 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EKX42107.1 - 0.0011 18.7 0.1 0.0028 17.4 0.1 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain Pox_G9-A16 PF03003.16 EKX42107.1 - 0.3 10.8 2.0 1.5 8.6 1.8 2.1 2 0 0 2 2 2 0 Pox virus entry-fusion-complex G9/A16 Abhydrolase_6 PF12697.7 EKX42108.1 - 1.4e-13 51.9 0.8 2.6e-13 51.1 0.8 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EKX42108.1 - 1.3e-07 31.2 0.0 2.1e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EKX42108.1 - 9.3e-07 28.7 0.3 1.5e-06 28.1 0.3 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 EKX42108.1 - 0.016 14.2 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme SSP160 PF06933.11 EKX42108.1 - 0.018 13.3 2.1 0.022 13.0 2.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Chlorophyllase PF07224.11 EKX42108.1 - 0.059 12.4 0.0 0.09 11.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Thioesterase PF00975.20 EKX42108.1 - 0.19 11.8 1.0 0.51 10.4 0.1 2.0 1 1 1 2 2 2 0 Thioesterase domain SR-25 PF10500.9 EKX42108.1 - 0.19 11.3 12.6 0.29 10.7 12.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PGAP1 PF07819.13 EKX42108.1 - 0.2 11.3 0.3 0.55 9.9 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein UPF0561 PF10573.9 EKX42109.1 - 0.0075 16.4 1.6 0.032 14.3 1.6 2.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0561 DUF2512 PF10710.9 EKX42110.1 - 0.002 17.8 0.1 0.002 17.8 0.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2512) ELO PF01151.18 EKX42111.1 - 1.6e-19 70.4 11.1 2.6e-19 69.7 11.1 1.2 1 0 0 1 1 1 1 GNS1/SUR4 family Patatin PF01734.22 EKX42111.1 - 0.0093 16.2 0.6 0.19 11.9 0.6 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase PPR_3 PF13812.6 EKX42112.1 - 2.9e-31 107.3 0.0 2.1e-07 30.9 0.0 6.6 5 1 2 7 7 7 5 Pentatricopeptide repeat domain PPR_2 PF13041.6 EKX42112.1 - 1e-27 96.1 0.2 3.5e-06 27.1 0.0 8.1 8 1 1 9 9 9 6 PPR repeat family PPR_long PF17177.4 EKX42112.1 - 1.7e-17 63.5 0.1 2.9e-12 46.4 0.1 4.1 2 1 2 4 4 4 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EKX42112.1 - 2e-10 40.2 20.7 0.039 13.7 0.0 9.0 10 0 0 10 10 10 3 PPR repeat ECSIT PF06239.11 EKX42112.1 - 0.00032 19.9 0.0 7.7 5.6 0.0 4.3 3 2 1 4 4 4 2 Evolutionarily conserved signalling intermediate in Toll pathway Exog_C PF18026.1 EKX42112.1 - 0.0092 16.0 0.0 10 6.3 0.0 3.7 3 0 0 3 3 3 1 Endo/exonuclease (EXOG) C-terminal domain tRNA_edit PF04073.15 EKX42113.1 - 5.6e-15 55.5 0.0 6.9e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Pkinase PF00069.25 EKX42114.1 - 1e-31 110.3 0.0 3.6e-31 108.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX42114.1 - 3.6e-23 82.2 0.1 1.9e-21 76.6 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX42114.1 - 7.3e-05 21.7 0.9 0.00018 20.4 0.9 1.8 1 1 0 1 1 1 1 Fungal protein kinase SSF PF00474.17 EKX42116.1 - 9.5e-11 41.2 24.3 9.5e-11 41.2 24.3 2.6 2 1 0 2 2 2 1 Sodium:solute symporter family Pkinase PF00069.25 EKX42117.1 - 3e-25 89.1 0.0 3.3e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX42117.1 - 1.9e-14 53.6 0.0 2e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX42117.1 - 0.0021 16.9 0.1 0.0023 16.8 0.1 1.0 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX42117.1 - 0.019 14.9 0.0 0.02 14.8 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-TRAF PF02176.18 EKX42118.1 - 0.097 13.4 0.3 2.1 9.1 0.3 2.2 1 1 0 1 1 1 0 TRAF-type zinc finger Hira PF07569.11 EKX42119.1 - 0.094 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 TUP1-like enhancer of split MORN PF02493.20 EKX42120.1 - 3.1e-54 177.7 69.3 8.6e-07 28.5 0.1 11.1 11 0 0 11 11 11 11 MORN repeat DUF3048_C PF17479.2 EKX42120.1 - 0.21 12.0 9.1 9.7 6.6 0.1 4.1 2 2 1 4 4 4 0 Protein of unknown function (DUF3048) C-terminal domain Ephrin_rec_like PF07699.13 EKX42121.1 - 1.8e-09 37.2 23.3 1.2e-05 25.0 1.9 4.1 2 1 2 4 4 4 4 Putative ephrin-receptor like NCD3G PF07562.14 EKX42121.1 - 4.5e-08 32.9 15.8 0.0037 17.2 2.1 3.8 2 1 1 3 3 3 3 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX42121.1 - 0.0015 18.9 19.5 0.5 10.8 1.1 4.7 2 2 2 4 4 4 4 TNFR/NGFR cysteine-rich region VSP PF03302.13 EKX42121.1 - 0.0019 17.1 9.8 0.0049 15.8 3.9 2.1 1 1 1 2 2 2 2 Giardia variant-specific surface protein DUF2318 PF10080.9 EKX42121.1 - 0.14 12.3 2.6 4.7 7.4 0.1 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) Med3 PF11593.8 EKX42121.1 - 0.16 11.1 3.0 0.19 10.9 3.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal IMUP PF15761.5 EKX42121.1 - 0.19 12.4 6.6 0.25 12.0 6.6 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein Furin-like_2 PF15913.5 EKX42121.1 - 1 9.5 8.2 0.34 11.1 0.8 2.4 1 1 1 2 2 2 0 Furin-like repeat, cysteine-rich SR-25 PF10500.9 EKX42121.1 - 2.9 7.4 15.1 3.7 7.1 15.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pentapeptide_4 PF13599.6 EKX42122.1 - 0.044 13.9 0.1 0.078 13.2 0.1 1.4 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) THEG4 PF15834.5 EKX42122.1 - 4.5 7.2 6.9 0.77 9.7 0.2 2.4 2 1 1 3 3 3 0 Testis highly expressed protein 4 LRR_6 PF13516.6 EKX42123.1 - 7.2e-38 125.4 41.4 0.0012 18.7 0.1 13.4 13 0 0 13 13 13 10 Leucine Rich repeat LRR_8 PF13855.6 EKX42123.1 - 8.4e-07 28.7 38.2 3.5e-05 23.5 2.1 9.0 9 2 0 10 10 10 4 Leucine rich repeat LRR_4 PF12799.7 EKX42123.1 - 1.7e-06 28.2 36.8 0.073 13.5 1.3 9.4 5 3 4 9 9 9 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX42123.1 - 0.00073 19.7 31.6 16 6.5 0.0 11.7 12 1 0 12 12 12 2 Leucine Rich Repeat CHAT PF12770.7 EKX42124.1 - 1.7e-21 76.9 0.0 2.1e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 CHAT domain YobH PF13996.6 EKX42126.1 - 0.013 15.5 0.1 2.6 8.2 0.0 2.2 2 0 0 2 2 2 0 YobH-like protein Pkinase PF00069.25 EKX42127.1 - 2.7e-41 141.7 0.0 7.6e-29 100.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EKX42127.1 - 2.2e-20 73.1 0.0 2.7e-13 49.8 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase FliT PF05400.13 EKX42127.1 - 0.027 15.3 2.8 0.087 13.7 0.2 3.2 3 0 0 3 3 3 0 Flagellar protein FliT GIT_CC PF16559.5 EKX42127.1 - 0.033 14.1 0.3 0.12 12.3 0.3 2.0 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor FTA2 PF13095.6 EKX42127.1 - 0.13 11.8 0.0 7.3 6.2 0.0 2.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 MORN PF02493.20 EKX42128.1 - 6.7e-15 54.0 0.5 3.9e-07 29.6 0.4 2.2 2 0 0 2 2 2 2 MORN repeat MORN PF02493.20 EKX42129.1 - 2.2e-12 46.1 13.8 0.0001 21.9 0.6 3.9 4 0 0 4 4 4 3 MORN repeat YXWGXW PF12779.7 EKX42129.1 - 0.0013 18.9 2.1 0.006 16.7 0.6 2.2 2 0 0 2 2 2 1 YXWGXW repeat (2 copies) PDZ_2 PF13180.6 EKX42131.1 - 0.00066 19.9 0.0 0.0015 18.8 0.0 1.7 1 1 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX42131.1 - 0.0012 19.1 0.0 0.0034 17.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX42131.1 - 0.0046 16.8 0.0 0.018 14.9 0.0 2.2 1 0 0 1 1 1 1 PDZ domain Atg14 PF10186.9 EKX42131.1 - 0.0058 15.7 12.1 0.009 15.1 12.1 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 FapA PF03961.13 EKX42131.1 - 0.027 13.1 5.4 0.039 12.6 5.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A CENP-K PF11802.8 EKX42131.1 - 0.029 14.0 16.5 0.14 11.7 15.9 2.2 1 1 1 2 2 2 0 Centromere-associated protein K PDZ_4 PF17816.1 EKX42131.1 - 0.074 13.5 0.0 0.24 11.8 0.0 1.9 1 0 0 1 1 1 0 PDZ domain ATG16 PF08614.11 EKX42131.1 - 0.075 13.2 24.7 0.045 14.0 19.4 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) PIEZO PF15917.5 EKX42131.1 - 0.18 11.3 3.6 0.32 10.4 3.6 1.4 1 0 0 1 1 1 0 Piezo Tricorn_PDZ PF14685.6 EKX42131.1 - 0.18 11.8 0.4 0.55 10.2 0.0 1.9 2 0 0 2 2 2 0 Tricorn protease PDZ domain Cnn_1N PF07989.11 EKX42131.1 - 0.26 11.5 17.6 0.67 10.1 11.4 3.3 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF745 PF05335.13 EKX42131.1 - 3.2 7.5 10.8 1.2 8.9 5.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF745) BRE1 PF08647.11 EKX42131.1 - 3.6 7.7 13.7 10 6.3 11.3 2.4 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Seryl_tRNA_N PF02403.22 EKX42131.1 - 7 6.9 12.5 35 4.7 0.1 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TMPIT PF07851.13 EKX42131.1 - 7.5 5.7 11.9 4.9 6.3 8.5 2.0 1 1 1 2 2 2 0 TMPIT-like protein Med30 PF11315.8 EKX42131.1 - 8.9 6.5 11.3 5.9 7.1 5.7 2.4 1 1 1 2 2 2 0 Mediator complex subunit 30 AAA PF00004.29 EKX42133.1 - 2.6e-07 31.1 0.0 5.6e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EKX42133.1 - 0.016 15.0 0.1 0.11 12.2 0.1 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_lid_6 PF17866.1 EKX42133.1 - 0.038 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA lid domain Vps51 PF08700.11 EKX42133.1 - 0.08 13.0 4.0 0.045 13.8 1.5 2.0 2 0 0 2 2 2 0 Vps51/Vps67 CPSase_L_D3 PF02787.19 EKX42133.1 - 0.091 13.1 0.3 0.32 11.4 0.3 1.9 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain DUF913 PF06025.12 EKX42133.1 - 0.12 11.4 2.7 5.6 5.8 1.4 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF1192 PF06698.11 EKX42133.1 - 1.1 9.4 4.6 3.7 7.7 4.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) ERO1 PF04137.15 EKX42134.1 - 8.3e-95 318.0 0.0 1.3e-94 317.3 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Cyt-b5 PF00173.28 EKX42134.1 - 2.1e-14 53.4 0.0 4.2e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Kinesin PF00225.23 EKX42136.1 - 8.3e-95 317.5 0.1 1.4e-94 316.8 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX42136.1 - 9.9e-18 64.5 0.0 2.2e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Ephrin_rec_like PF07699.13 EKX42138.1 - 4.3e-46 154.4 105.6 6.7e-11 41.8 6.7 10.8 5 4 6 11 11 11 10 Putative ephrin-receptor like DUF2318 PF10080.9 EKX42138.1 - 9.8 6.4 61.7 0.11 12.7 5.9 6.5 1 1 4 6 6 6 0 Predicted membrane protein (DUF2318) TPR_12 PF13424.6 EKX42139.1 - 2.7e-47 158.9 66.0 8e-07 29.3 0.0 18.9 19 2 1 21 21 20 10 Tetratricopeptide repeat TPR_10 PF13374.6 EKX42139.1 - 9.1e-12 44.4 38.4 0.12 12.3 0.0 17.4 19 1 1 20 20 19 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX42139.1 - 9.9e-11 41.6 50.0 0.22 10.9 0.1 11.8 7 3 3 13 13 13 6 MalT-like TPR region cNMP_binding PF00027.29 EKX42139.1 - 5.8e-08 32.7 0.3 2.1e-07 30.9 0.1 2.2 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain TPR_16 PF13432.6 EKX42139.1 - 1.9e-07 31.6 17.3 2.4 8.9 0.0 11.4 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX42139.1 - 3.7e-07 29.7 42.8 0.0018 18.0 0.1 13.7 16 0 0 16 16 16 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX42139.1 - 2e-05 24.3 27.8 1.8 8.8 0.0 12.0 15 0 0 15 15 12 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX42139.1 - 4.3e-05 23.4 46.5 0.013 15.7 0.0 15.2 19 0 0 19 19 16 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX42139.1 - 0.0023 18.4 48.9 0.39 11.2 0.8 14.7 16 3 1 17 17 16 2 Tetratricopeptide repeat MIT PF04212.18 EKX42139.1 - 0.0036 17.3 15.0 17 5.6 0.1 8.3 10 0 0 10 10 7 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 EKX42139.1 - 0.0055 16.7 81.9 0.1 12.8 0.2 20.5 26 0 0 26 26 23 3 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EKX42139.1 - 0.012 15.6 4.2 0.43 10.6 0.1 5.2 7 0 0 7 7 6 0 Putative TPR-like repeat PPR_2 PF13041.6 EKX42139.1 - 0.14 12.3 0.0 3.8 7.8 0.1 3.2 2 0 0 2 2 2 0 PPR repeat family PPR PF01535.20 EKX42139.1 - 0.18 12.1 5.8 9.5 6.7 0.0 6.6 7 0 0 7 7 6 0 PPR repeat TPR_11 PF13414.6 EKX42139.1 - 0.25 11.1 23.0 2.9 7.7 0.0 8.3 9 0 0 9 9 9 0 TPR repeat ANAPC3 PF12895.7 EKX42139.1 - 0.63 10.3 38.5 0.93 9.8 0.1 12.4 12 5 1 13 13 12 0 Anaphase-promoting complex, cyclosome, subunit 3 Dpy-30 PF05186.13 EKX42141.1 - 1.7e-13 50.0 0.0 2.4e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif RIIa PF02197.17 EKX42141.1 - 0.02 14.5 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Toxin_31 PF08119.11 EKX42143.1 - 0.00026 20.6 4.6 18 5.2 0.0 6.1 1 1 6 7 7 7 2 Scorpion acidic alpha-KTx toxin family Glyco_hydro_49N PF17433.2 EKX42143.1 - 0.098 12.3 1.7 33 4.0 0.0 3.2 1 1 1 3 3 3 0 Glycosyl hydrolase family 49 N-terminal Ig-like domain Cytochrom_C1 PF02167.15 EKX42144.1 - 2.6e-94 315.1 0.0 5.2e-94 314.0 0.0 1.5 2 0 0 2 2 2 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 EKX42144.1 - 0.00012 22.3 0.1 0.00026 21.2 0.1 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EKX42144.1 - 0.02 16.0 1.9 0.036 15.2 1.3 1.9 2 1 0 2 2 2 0 Cytochrome c PKcGMP_CC PF16808.5 EKX42145.1 - 0.0076 16.1 0.3 0.0076 16.1 0.3 4.9 4 1 1 5 5 5 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Shugoshin_N PF07558.11 EKX42145.1 - 0.052 13.4 0.1 0.052 13.4 0.1 4.0 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region SlyX PF04102.12 EKX42145.1 - 0.061 13.9 14.7 4.5 7.9 4.1 4.1 4 0 0 4 4 3 0 SlyX MtrG PF04210.13 EKX42145.1 - 0.81 9.6 6.7 7.8 6.4 0.2 4.2 4 1 1 5 5 5 0 Tetrahydromethanopterin S-methyltransferase, subunit G KxDL PF10241.9 EKX42145.1 - 1.3 9.3 11.2 2.7 8.3 1.4 4.4 3 1 0 4 4 4 0 Uncharacterized conserved protein LMBR1 PF04791.16 EKX42145.1 - 1.5 7.6 7.2 2 7.3 7.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Nup54 PF13874.6 EKX42145.1 - 3.8 7.6 13.3 1.9 8.6 9.7 2.4 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 MscS_porin PF12795.7 EKX42145.1 - 6.1 6.3 26.8 0.33 10.5 19.2 2.6 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain FlaC_arch PF05377.11 EKX42145.1 - 6.2 7.3 20.2 4.4 7.8 4.0 5.2 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) CENP-F_leu_zip PF10473.9 EKX42145.1 - 6.7 6.7 37.6 0.74 9.8 11.5 4.4 3 2 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TolA_bind_tri PF16331.5 EKX42145.1 - 7.5 6.7 17.1 0.072 13.2 3.5 3.6 4 0 0 4 4 4 0 TolA binding protein trimerisation DUF4407 PF14362.6 EKX42145.1 - 8 5.7 12.6 18 4.6 12.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Pox_A_type_inc PF04508.12 EKX42145.1 - 9.5 6.3 21.2 5.9 6.9 0.3 5.6 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat REJ PF02010.15 EKX42146.1 - 1.4e-20 73.5 0.3 1.1e-12 47.5 0.0 2.7 1 1 1 2 2 2 2 REJ domain TIG PF01833.24 EKX42146.1 - 2.4e-18 66.0 31.7 9.2e-07 28.9 1.1 6.4 6 0 0 6 6 6 4 IPT/TIG domain TIG PF01833.24 EKX42147.1 - 3.2e-21 75.2 28.2 1.8e-07 31.1 0.4 7.1 7 0 0 7 7 7 5 IPT/TIG domain Prenyltrans PF00432.21 EKX42148.1 - 0.0024 17.6 0.1 3.2 7.6 0.0 2.5 2 0 0 2 2 2 2 Prenyltransferase and squalene oxidase repeat zf-CDGSH PF09360.10 EKX42148.1 - 0.02 15.1 1.2 7.8 6.8 0.1 2.6 2 0 0 2 2 2 0 Iron-binding zinc finger CDGSH type EndIII_4Fe-2S PF10576.9 EKX42148.1 - 7.7 7.0 7.9 26 5.3 1.0 2.5 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III LAX PF15681.5 EKX42150.1 - 0.0047 15.8 0.1 1.8 7.3 0.0 2.2 2 0 0 2 2 2 2 Lymphocyte activation family X DUF5439 PF17507.2 EKX42151.1 - 0.61 10.3 2.9 1.7 8.9 0.2 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5439) HATPase_c_3 PF13589.6 EKX42153.1 - 0.00066 19.5 0.3 0.002 17.9 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SMC_hinge PF06470.13 EKX42153.1 - 0.0089 16.3 0.0 0.022 15.0 0.0 1.7 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain DUF3301 PF11743.8 EKX42154.1 - 0.091 12.4 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) PDZ PF00595.24 EKX42155.1 - 2.4e-10 40.6 0.4 6e-10 39.4 0.4 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX42155.1 - 1.6e-07 31.0 1.5 3.5e-07 30.0 0.3 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX42155.1 - 9e-05 22.7 0.3 0.00029 21.1 0.3 1.9 1 0 0 1 1 1 1 PDZ domain bZIP_1 PF00170.21 EKX42155.1 - 0.0003 20.8 2.3 0.0003 20.8 2.3 4.9 5 1 0 5 5 5 1 bZIP transcription factor Leu_zip PF15294.6 EKX42155.1 - 0.0021 17.6 16.7 0.0021 17.6 16.7 3.9 2 1 1 4 4 4 1 Leucine zipper Spc7 PF08317.11 EKX42155.1 - 0.0023 16.9 23.2 0.0023 16.9 23.2 4.3 3 1 1 4 4 4 3 Spc7 kinetochore protein HOOK PF05622.12 EKX42155.1 - 0.026 12.7 51.9 0.0054 15.0 22.0 3.7 2 1 1 3 3 3 0 HOOK protein PX PF00787.24 EKX42155.1 - 0.043 13.8 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 PX domain Gon7 PF08738.10 EKX42155.1 - 1.2 9.3 13.9 1.8 8.7 0.4 3.7 2 1 1 3 3 3 0 Gon7 family Atg14 PF10186.9 EKX42155.1 - 2.3 7.2 49.4 0.28 10.2 2.5 4.5 3 1 2 5 5 5 0 Vacuolar sorting 38 and autophagy-related subunit 14 CorA PF01544.18 EKX42155.1 - 3.7 6.8 19.2 0.21 10.8 1.5 2.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein F5_F8_type_C PF00754.25 EKX42156.1 - 0.0051 16.9 0.3 0.0095 16.0 0.3 1.4 1 0 0 1 1 1 1 F5/8 type C domain XG_FTase PF03254.13 EKX42156.1 - 0.1 11.2 0.0 0.33 9.5 0.0 1.7 2 0 0 2 2 2 0 Xyloglucan fucosyltransferase Ion_trans PF00520.31 EKX42157.1 - 1.4e-32 112.9 9.0 1.9e-32 112.5 9.0 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX42157.1 - 5.8e-14 51.8 4.0 5.8e-14 51.8 4.0 2.0 2 1 0 2 2 2 1 Ion channel BTB_2 PF02214.22 EKX42157.1 - 1e-07 32.2 0.0 2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 EKX42157.1 - 0.0041 17.2 0.0 0.022 14.8 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain DUF2976 PF11190.8 EKX42157.1 - 0.067 13.0 0.4 30 4.5 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) TauD PF02668.16 EKX42159.1 - 1.6e-27 97.0 0.0 2.5e-27 96.3 0.0 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 EKX42159.1 - 0.0029 16.8 0.0 0.0061 15.7 0.0 1.5 1 0 0 1 1 1 1 CsiD ApoA-II PF04711.13 EKX42159.1 - 0.029 14.5 0.0 0.096 12.9 0.0 1.8 2 0 0 2 2 2 0 Apolipoprotein A-II (ApoA-II) TetR_C_8 PF14278.6 EKX42159.1 - 0.096 12.8 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator C-terminal region MIB_HERC2 PF06701.13 EKX42160.1 - 0.077 13.3 0.2 0.13 12.5 0.2 1.4 1 0 0 1 1 1 0 Mib_herc2 Collagen PF01391.18 EKX42161.1 - 0.00046 19.9 21.9 0.00086 19.0 21.9 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) WD40_alt PF14077.6 EKX42161.1 - 5.1 7.0 8.3 0.11 12.4 0.6 2.3 2 0 0 2 2 2 0 Alternative WD40 repeat motif TPR_12 PF13424.6 EKX42162.1 - 3.5e-56 187.4 13.5 1.8e-23 82.6 0.3 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX42162.1 - 5.7e-48 159.5 16.5 7.2e-12 44.8 0.2 5.1 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.6 EKX42162.1 - 4.7e-37 123.3 9.1 2.2e-09 36.7 0.2 5.5 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 EKX42162.1 - 1e-28 97.9 9.0 4.1e-06 26.4 0.0 5.3 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 EKX42162.1 - 4.1e-21 73.4 10.1 0.0037 17.4 0.1 5.8 5 1 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 EKX42162.1 - 3.5e-19 67.3 17.1 6e-05 22.9 0.1 5.9 5 1 0 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 EKX42162.1 - 2e-14 53.0 12.6 0.011 16.4 0.3 5.8 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EKX42162.1 - 1.2e-12 47.3 9.0 0.052 13.9 0.0 5.7 5 2 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 EKX42162.1 - 1.6e-11 44.6 12.5 0.0001 22.9 0.3 4.2 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EKX42162.1 - 1.7e-11 44.4 11.2 0.00012 22.5 0.4 4.3 3 1 2 5 5 5 4 Tetratricopeptide repeat SNAP PF14938.6 EKX42162.1 - 1.6e-09 37.6 0.0 2.1e-06 27.4 0.0 2.1 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP 14-3-3 PF00244.20 EKX42162.1 - 3.3e-09 36.6 0.7 4e-07 29.8 0.2 2.5 1 1 1 2 2 2 1 14-3-3 protein TPR_MalT PF17874.1 EKX42162.1 - 8.3e-09 35.3 4.6 0.00014 21.3 0.5 2.1 1 1 1 2 2 2 2 MalT-like TPR region TPR_4 PF07721.14 EKX42162.1 - 8.8e-09 35.2 3.4 0.087 13.5 0.0 5.6 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX42162.1 - 3.3e-08 33.6 4.1 4.1 8.2 0.0 5.7 5 1 0 5 5 5 1 Tetratricopeptide repeat MIT PF04212.18 EKX42162.1 - 1.6e-07 31.3 5.0 4.3 7.5 0.0 5.1 2 2 3 5 5 5 1 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 EKX42162.1 - 1e-06 28.9 3.1 0.00027 21.1 0.2 3.5 1 1 3 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_5 PF12688.7 EKX42162.1 - 1.9e-05 24.9 5.4 0.48 10.7 0.8 4.2 2 2 1 3 3 3 1 Tetratrico peptide repeat BTAD PF03704.17 EKX42162.1 - 0.00045 20.7 5.6 0.063 13.7 2.8 2.9 1 1 1 2 2 2 1 Bacterial transcriptional activator domain PPR PF01535.20 EKX42162.1 - 0.00054 20.0 3.9 16 6.0 0.0 5.6 6 1 1 7 7 7 0 PPR repeat TPR_15 PF13429.6 EKX42162.1 - 0.00093 18.5 6.2 1.4 8.0 2.7 4.4 2 2 1 3 3 3 1 Tetratricopeptide repeat DUF2225 PF09986.9 EKX42162.1 - 0.0013 18.5 0.1 0.026 14.2 0.1 2.2 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_9 PF13371.6 EKX42162.1 - 0.0025 17.9 8.3 0.56 10.4 0.0 4.7 1 1 4 5 5 5 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 EKX42162.1 - 0.0054 16.2 0.3 1.4 8.5 0.0 3.2 3 0 0 3 3 2 1 SHNi-TPR ANAPC5 PF12862.7 EKX42162.1 - 0.0056 16.7 2.2 0.27 11.3 0.2 3.6 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 5 DUF4404 PF14357.6 EKX42162.1 - 0.0063 17.1 0.3 0.22 12.2 0.1 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4404) RPN7 PF10602.9 EKX42162.1 - 0.0064 16.2 1.5 15 5.3 0.1 3.9 3 1 1 4 4 4 0 26S proteasome subunit RPN7 TPR_11 PF13414.6 EKX42162.1 - 0.0069 16.0 11.2 6.2 6.6 0.7 5.1 5 1 1 6 6 5 0 TPR repeat Fis1_TPR_C PF14853.6 EKX42162.1 - 0.01 15.9 7.4 2.7 8.2 0.1 4.3 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat HrpB7 PF09486.10 EKX42162.1 - 0.081 13.3 0.1 0.53 10.7 0.0 2.0 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) TAF1_subA PF14929.6 EKX42162.1 - 0.14 11.5 0.2 0.45 9.9 0.0 1.7 1 1 0 2 2 2 0 TAF RNA Polymerase I subunit A PPR_2 PF13041.6 EKX42162.1 - 0.21 11.8 0.1 38 4.6 0.0 3.6 4 1 1 5 5 4 0 PPR repeat family RWP-RK PF02042.15 EKX42163.1 - 2e-11 43.7 0.0 4.3e-11 42.6 0.0 1.6 1 1 0 1 1 1 1 RWP-RK domain PPP4R2 PF09184.11 EKX42163.1 - 0.0022 17.6 11.5 0.0022 17.6 11.5 2.1 2 0 0 2 2 2 1 PPP4R2 Mito_fiss_reg PF05308.11 EKX42163.1 - 0.33 11.0 7.4 0.69 10.0 7.4 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator Nop14 PF04147.12 EKX42163.1 - 3.6 5.7 35.3 5.2 5.2 35.3 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EKX42163.1 - 6.8 4.7 37.6 9.2 4.2 37.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi AAA_12 PF13087.6 EKX42164.1 - 1.1e-41 142.7 0.0 1.3e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EKX42164.1 - 4.9e-05 23.2 0.1 6.1e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 EKX42164.1 - 0.00022 21.0 0.1 0.00045 20.0 0.1 1.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Fz PF01392.22 EKX42165.1 - 4.2e-05 24.1 7.2 0.00044 20.8 6.9 2.1 1 1 0 1 1 1 1 Fz domain tRNA-synt_2d PF01409.20 EKX42167.1 - 2e-48 165.0 0.1 5.9e-48 163.5 0.1 1.7 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 EKX42167.1 - 1e-25 90.0 0.0 2.1e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.20 EKX42167.1 - 0.0019 17.3 0.0 0.34 9.9 0.0 2.3 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) Ldh_2 PF02615.14 EKX42168.1 - 1.2e-102 343.6 0.1 1.3e-102 343.4 0.1 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase MORN PF02493.20 EKX42169.1 - 7.9e-56 182.8 75.8 9.9e-07 28.3 0.2 13.4 13 1 0 13 13 13 13 MORN repeat 2OG-FeII_Oxy_3 PF13640.6 EKX42172.1 - 3.7e-06 27.8 0.0 7.9e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily U79_P34 PF03064.16 EKX42172.1 - 0.079 12.3 4.4 0.11 11.9 4.4 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF347 PF03988.12 EKX42172.1 - 0.13 12.5 0.0 1.8 8.8 0.1 2.2 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) CENP-N PF05238.13 EKX42172.1 - 0.25 10.6 5.6 0.32 10.3 5.6 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like DUF3464 PF11947.8 EKX42172.1 - 0.27 11.0 2.8 2.1 8.1 2.9 2.1 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 CPSF100_C PF13299.6 EKX42172.1 - 0.4 10.9 6.3 0.64 10.2 6.3 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal AAA_23 PF13476.6 EKX42172.1 - 0.42 11.1 7.7 0.59 10.6 7.7 1.2 1 0 0 1 1 1 0 AAA domain RPN2_C PF18004.1 EKX42172.1 - 1.2 9.0 11.3 2.1 8.3 11.3 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RR_TM4-6 PF06459.12 EKX42172.1 - 2.5 7.9 9.3 3.1 7.5 9.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4746 PF15928.5 EKX42172.1 - 2.7 7.3 12.8 3.9 6.8 12.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Roughex PF06020.11 EKX42172.1 - 3.8 6.5 10.3 5.5 6.0 10.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Presenilin PF01080.17 EKX42172.1 - 5 5.8 7.3 6 5.5 7.3 1.1 1 0 0 1 1 1 0 Presenilin NARP1 PF12569.8 EKX42172.1 - 6.3 5.6 11.5 7.8 5.3 11.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GBP PF02263.19 EKX42173.1 - 4.5e-71 239.2 0.1 5.3e-71 238.9 0.1 1.0 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 EKX42173.1 - 1.8e-06 27.6 0.0 6.7e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 Guanylate-binding protein, C-terminal domain MMR_HSR1 PF01926.23 EKX42173.1 - 0.14 12.2 0.1 0.34 11.0 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase LRR_8 PF13855.6 EKX42174.1 - 2.5e-58 193.7 27.7 7.3e-15 54.5 1.7 3.9 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 EKX42174.1 - 1.5e-18 66.5 10.2 5.7e-06 26.6 1.0 4.2 1 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX42174.1 - 6.5e-14 52.0 0.0 2.8e-07 30.6 0.0 2.0 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EKX42174.1 - 9.2e-09 34.7 3.9 0.14 12.8 0.2 5.9 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_9 PF14580.6 EKX42174.1 - 0.0016 17.9 0.0 0.27 10.7 0.0 2.6 1 1 2 3 3 3 2 Leucine-rich repeat STE PF02200.16 EKX42174.1 - 0.061 13.7 0.0 11 6.5 0.0 3.4 1 1 3 4 4 4 0 STE like transcription factor LRR_6 PF13516.6 EKX42174.1 - 0.62 10.3 13.0 18 5.7 0.2 5.5 6 0 0 6 6 6 0 Leucine Rich repeat Rab5ip PF07019.12 EKX42174.1 - 0.73 10.5 10.1 30 5.3 3.9 4.5 2 1 1 3 3 3 0 Rab5-interacting protein (Rab5ip) TPR_1 PF00515.28 EKX42175.1 - 3e-05 23.7 1.7 0.0086 15.9 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX42175.1 - 3.7e-05 24.1 0.3 6.3e-05 23.4 0.3 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX42175.1 - 0.00015 21.6 2.6 0.051 13.7 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX42175.1 - 0.00027 21.1 0.7 0.0011 19.2 0.7 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX42175.1 - 0.0016 18.1 0.5 0.085 12.5 0.3 2.3 1 1 1 2 2 2 1 TPR repeat TPR_7 PF13176.6 EKX42175.1 - 0.0026 17.7 3.2 1.2 9.3 0.3 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.18 EKX42175.1 - 0.0027 17.7 2.3 0.1 12.7 0.3 2.3 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Exonuc_VII_S PF02609.16 EKX42175.1 - 0.012 15.6 1.8 3.2 7.9 0.0 2.3 2 0 0 2 2 2 0 Exonuclease VII small subunit Coatomer_E PF04733.14 EKX42175.1 - 0.015 14.7 0.1 0.016 14.7 0.1 1.1 1 0 0 1 1 1 0 Coatomer epsilon subunit THDPS_N PF14790.6 EKX42175.1 - 0.033 14.0 0.1 0.038 13.8 0.1 1.0 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal PSCyt3 PF07627.11 EKX42175.1 - 0.037 14.3 0.4 0.055 13.7 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1588) 4HB_MCP_1 PF12729.7 EKX42175.1 - 0.043 13.4 2.2 0.26 10.8 1.3 2.0 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction DUF4062 PF13271.6 EKX42175.1 - 0.081 13.3 0.2 0.11 12.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4062) TPR_8 PF13181.6 EKX42175.1 - 0.093 13.0 3.8 4.8 7.6 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 EKX42175.1 - 0.13 12.5 1.1 0.99 9.8 0.5 2.3 2 0 0 2 2 2 0 PPR repeat zf-UBP PF02148.19 EKX42176.1 - 0.002 18.4 1.2 0.64 10.4 0.0 3.2 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein zf-CSL PF05207.13 EKX42176.1 - 0.053 13.2 4.2 4.4 7.1 0.1 3.4 3 0 0 3 3 3 0 CSL zinc finger GFA PF04828.14 EKX42176.1 - 0.056 13.8 1.6 14 6.1 0.0 3.4 3 0 0 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme zf-C2HE PF16278.5 EKX42176.1 - 0.077 13.4 0.4 57 4.3 0.0 3.7 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Transpos_assoc PF13963.6 EKX42176.1 - 0.13 12.5 3.7 40 4.6 0.1 3.4 3 0 0 3 3 3 0 Transposase-associated domain Nudix_N_2 PF14803.6 EKX42176.1 - 0.16 11.9 3.3 19 5.3 0.0 3.9 3 0 0 3 3 3 0 Nudix N-terminal Zn_ribbon_SprT PF17283.2 EKX42176.1 - 0.24 11.3 4.8 2.8 7.9 0.2 3.1 3 0 0 3 3 3 0 SprT-like zinc ribbon domain DUF1644 PF07800.12 EKX42176.1 - 0.69 10.0 9.2 7.8 6.5 0.2 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1644) C1_4 PF07975.12 EKX42176.1 - 3.3 8.0 4.3 26 5.1 0.1 3.1 3 0 0 3 3 3 0 TFIIH C1-like domain zf-C2H2_4 PF13894.6 EKX42176.1 - 5.7 8.0 17.6 3 8.9 0.1 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger AIG1 PF04548.16 EKX42177.1 - 0.22 10.8 4.5 0.069 12.5 0.5 2.2 3 0 0 3 3 3 0 AIG1 family UCH PF00443.29 EKX42178.1 - 5.5e-25 88.3 0.0 5.5e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EKX42178.1 - 3.2e-09 36.8 0.2 4.7e-09 36.3 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Actin_micro PF17003.5 EKX42178.1 - 0.011 15.0 0.0 0.013 14.7 0.0 1.1 1 0 0 1 1 1 0 Putative actin-like family Peptidase_C98 PF15499.6 EKX42178.1 - 0.042 13.3 0.0 1.9 7.9 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Zn_Tnp_IS1595 PF12760.7 EKX42178.1 - 0.39 10.7 4.2 2.5 8.1 0.5 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-H2C2_2 PF13465.6 EKX42178.1 - 3.5 8.2 6.8 11 6.6 1.5 2.6 2 0 0 2 2 2 0 Zinc-finger double domain PDZ_6 PF17820.1 EKX42181.1 - 0.00021 21.1 0.0 0.00044 20.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX42181.1 - 0.077 13.0 0.0 0.25 11.3 0.0 1.9 1 0 0 1 1 1 0 Tricorn protease PDZ domain PepSY_TM PF03929.16 EKX42181.1 - 3.7 7.1 3.9 0.87 9.2 0.8 1.5 2 0 0 2 2 2 0 PepSY-associated TM region DUF1415 PF07209.12 EKX42182.1 - 3.5e-27 95.2 0.0 3.5e-27 95.2 0.0 2.4 3 1 0 3 3 3 1 Protein of unknown function (DUF1415) CxxCxxCC PF03692.15 EKX42182.1 - 8.6e-08 32.8 0.0 3.4e-07 30.8 0.0 2.0 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain DEP PF00610.21 EKX42183.1 - 1.1e-11 44.6 0.0 1.7e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Flu_PB2 PF00604.17 EKX42183.1 - 0.14 10.0 0.0 0.17 9.8 0.0 1.0 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB2 GGACT PF06094.12 EKX42184.1 - 1.3e-19 71.0 0.1 2e-19 70.4 0.1 1.3 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 EKX42184.1 - 0.00066 20.0 0.3 0.0015 18.9 0.0 1.8 2 1 0 2 2 2 1 AIG2-like family FA_desaturase PF00487.24 EKX42186.1 - 0.07 13.0 1.2 0.17 11.7 1.2 1.6 1 0 0 1 1 1 0 Fatty acid desaturase RRM_1 PF00076.22 EKX42187.1 - 8.6e-08 31.9 0.0 1.5e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EKX42187.1 - 0.077 13.0 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Ion_trans PF00520.31 EKX42188.1 - 0.055 12.7 6.3 0.015 14.6 3.3 1.5 2 0 0 2 2 2 0 Ion transport protein MCM2_N PF12619.8 EKX42188.1 - 1.7 8.9 10.0 2 8.7 8.2 2.0 2 1 0 2 2 2 0 Mini-chromosome maintenance protein 2 HAUS-augmin3 PF14932.6 EKX42189.1 - 0.0031 17.1 6.9 0.0063 16.1 6.9 1.5 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 ATG16 PF08614.11 EKX42189.1 - 0.008 16.4 13.9 0.008 16.4 13.9 2.1 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) PKcGMP_CC PF16808.5 EKX42189.1 - 0.014 15.2 1.2 0.014 15.2 1.2 3.4 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Csm1_N PF18504.1 EKX42189.1 - 0.056 13.8 10.6 1.5 9.2 1.4 2.7 2 0 0 2 2 2 0 Csm1 N-terminal domain YpzG PF14139.6 EKX42189.1 - 0.078 13.2 0.4 0.17 12.1 0.4 1.5 1 0 0 1 1 1 0 YpzG-like protein V_ATPase_I PF01496.19 EKX42189.1 - 0.25 9.2 2.2 0.38 8.6 2.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CALCOCO1 PF07888.11 EKX42189.1 - 4.4 6.1 22.7 3 6.6 15.4 2.2 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Methyltransf_16 PF10294.9 EKX42191.1 - 5.5e-23 81.6 0.0 1.1e-22 80.6 0.0 1.4 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 EKX42191.1 - 0.0022 18.7 0.0 0.0038 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EKX42191.1 - 0.065 12.6 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EKX42191.1 - 0.069 12.7 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.20 EKX42191.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase SseC PF04888.12 EKX42192.1 - 0.0046 16.6 1.4 0.0046 16.6 1.4 2.2 3 0 0 3 3 3 1 Secretion system effector C (SseC) like family ATP-synt PF00231.19 EKX42193.1 - 3.3e-73 246.8 3.3 3.8e-73 246.6 3.3 1.0 1 0 0 1 1 1 1 ATP synthase eIF2_C PF09173.11 EKX42194.1 - 1.1e-36 124.9 0.3 2.7e-36 123.7 0.3 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EKX42194.1 - 3.7e-21 75.6 2.9 1.9e-19 69.9 2.9 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EKX42194.1 - 1.1e-10 41.7 0.4 1.1e-10 41.7 0.4 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 EKX42194.1 - 0.0012 18.8 0.6 0.1 12.5 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EKX42194.1 - 0.0045 17.1 0.0 0.014 15.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase C2 PF00168.30 EKX42195.1 - 0.013 15.8 0.2 0.21 11.9 0.0 2.4 2 0 0 2 2 2 0 C2 domain TFIIA PF03153.13 EKX42196.1 - 0.0027 17.8 17.3 0.0027 17.8 17.3 2.3 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Ion_trans PF00520.31 EKX42196.1 - 0.063 12.5 14.0 0.01 15.1 5.1 2.6 3 0 0 3 3 3 0 Ion transport protein SpoIIIAH PF12685.7 EKX42196.1 - 1.8 8.4 11.0 0.17 11.7 0.5 2.9 3 0 0 3 3 3 0 SpoIIIAH-like protein RRN3 PF05327.11 EKX42196.1 - 4.8 5.6 21.8 0.035 12.6 13.2 1.8 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Toxin_TOLIP PF00087.21 EKX42197.1 - 0.052 13.8 8.5 0.054 13.8 2.8 2.6 2 1 0 2 2 2 0 Snake toxin and toxin-like protein PTS_IIB PF02302.17 EKX42198.1 - 0.0037 17.9 11.3 2.6 8.8 0.3 3.5 3 0 0 3 3 3 3 PTS system, Lactose/Cellobiose specific IIB subunit TOBE_2 PF08402.10 EKX42198.1 - 0.053 13.7 2.4 8.5 6.6 0.2 2.5 2 0 0 2 2 2 0 TOBE domain Cas_Csm6 PF09659.10 EKX42198.1 - 0.086 11.6 1.2 0.13 11.0 1.2 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csm6) TPR_2 PF07719.17 EKX42199.1 - 2.2e-05 24.2 1.3 0.032 14.3 0.0 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX42199.1 - 0.0002 21.9 0.0 0.34 11.9 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX42199.1 - 0.0063 16.3 1.1 1.1 9.2 0.1 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX42199.1 - 0.013 15.9 0.1 6.3 7.4 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX42199.1 - 0.019 15.2 0.5 2.3 8.6 0.0 2.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EKX42199.1 - 0.042 13.5 0.1 0.13 12.0 0.1 1.8 2 0 0 2 2 2 0 TPR repeat Hydrolase_4 PF12146.8 EKX42200.1 - 1.1e-07 31.4 0.0 1e-05 25.0 0.0 2.0 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DUF1057 PF06342.12 EKX42200.1 - 0.00033 19.8 0.0 0.00038 19.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_3 PF07859.13 EKX42200.1 - 0.00042 20.2 0.0 0.00081 19.3 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 EKX42200.1 - 0.0034 17.0 0.0 1.8 8.1 0.0 2.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold 3HBOH PF10605.9 EKX42200.1 - 0.0084 14.4 0.0 0.0098 14.2 0.0 1.1 1 0 0 1 1 1 1 3HB-oligomer hydrolase (3HBOH) Abhydrolase_2 PF02230.16 EKX42200.1 - 0.012 15.4 0.0 0.41 10.4 0.0 2.1 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EKX42200.1 - 0.04 13.4 0.0 0.55 9.7 0.0 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family Mycoplasma_p37 PF06646.11 EKX42200.1 - 0.078 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 High affinity transport system protein p37 cNMP_binding PF00027.29 EKX42201.1 - 6.4e-08 32.6 0.0 9.6e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain CCDC24 PF15669.5 EKX42203.1 - 5.5e-22 78.6 4.4 1.4e-21 77.3 4.4 1.7 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 24 family zf-HC5HC2H_2 PF13832.6 EKX42204.1 - 2.5e-18 66.2 10.4 5.1e-18 65.3 6.7 2.6 2 1 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EKX42204.1 - 5.3e-08 33.0 4.0 5.3e-08 33.0 4.0 3.7 2 2 2 4 4 4 1 PHD-like zinc-binding domain TruB_C_2 PF16198.5 EKX42205.1 - 0.43 10.8 2.7 10 6.3 0.0 3.9 3 0 0 3 3 3 0 tRNA pseudouridylate synthase B C-terminal domain Sir1 PF11603.8 EKX42205.1 - 1.6 9.2 5.4 0.99 9.9 0.1 2.9 2 1 1 3 3 3 0 Regulatory protein Sir1 RRM_1 PF00076.22 EKX42208.1 - 7.9e-17 60.8 0.0 1.3e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EKX42208.1 - 0.0012 18.9 0.0 0.0026 17.8 0.0 1.5 1 0 0 1 1 1 1 Limkain b1 RRM_5 PF13893.6 EKX42208.1 - 0.033 13.8 0.0 0.077 12.6 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EKX42208.1 - 0.13 12.1 0.0 0.33 10.9 0.0 1.6 2 0 0 2 2 2 0 Occluded RNA-recognition motif ThiD2 PF17792.1 EKX42209.1 - 0.053 14.0 3.9 1.1 9.7 0.3 2.6 1 1 1 2 2 2 0 ThiD2 family PMEI PF04043.15 EKX42209.1 - 0.063 13.6 1.5 0.12 12.7 1.5 1.4 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor DUF4692 PF15763.5 EKX42209.1 - 5.2 7.5 16.4 14 6.2 0.4 2.2 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) LRR_9 PF14580.6 EKX42212.1 - 2.7e-12 46.6 1.6 6e-12 45.4 0.3 2.0 1 1 1 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 EKX42212.1 - 4.2e-10 39.7 20.0 0.00019 21.7 4.3 3.6 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX42212.1 - 3.5e-06 26.7 18.2 1.5e-05 24.7 7.8 3.2 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 EKX42212.1 - 5.7 7.9 13.4 51 5.0 0.4 4.9 4 0 0 4 4 4 0 Leucine Rich Repeat FAD_binding_7 PF03441.14 EKX42215.1 - 4.7e-65 218.9 3.6 4.7e-65 218.9 3.6 1.6 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EKX42215.1 - 4.5e-34 117.8 0.0 6.9e-34 117.2 0.0 1.2 1 0 0 1 1 1 1 DNA photolyase LRR_4 PF12799.7 EKX42216.1 - 2.4e-16 59.6 48.8 0.0024 18.2 2.4 11.4 1 1 13 14 14 14 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX42216.1 - 1.5e-12 47.1 49.3 3.4e-05 23.5 6.2 8.6 2 2 8 10 10 10 8 Leucine rich repeat LRR_6 PF13516.6 EKX42216.1 - 2.4e-09 36.5 57.8 0.21 11.7 0.1 15.1 17 0 0 17 17 17 5 Leucine Rich repeat LRR_9 PF14580.6 EKX42216.1 - 0.0066 16.0 7.1 0.053 13.0 0.4 4.1 1 1 3 4 4 4 1 Leucine-rich repeat LRR_1 PF00560.33 EKX42216.1 - 1.2 10.0 37.9 63 4.7 0.1 12.4 13 2 0 13 13 13 0 Leucine Rich Repeat LRR_2 PF07723.13 EKX42216.1 - 1.6 9.5 0.0 1.6 9.5 0.0 5.4 6 0 0 6 6 6 0 Leucine Rich Repeat RCC1 PF00415.18 EKX42217.1 - 1.7e-23 83.0 5.9 0.00018 22.1 0.0 5.7 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX42217.1 - 5.6e-17 61.1 17.5 2.2e-07 30.5 1.5 4.9 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 EKX42218.1 - 7.1e-15 55.2 0.3 9.9e-10 38.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX42218.1 - 9.4e-14 51.8 0.0 1.3e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX42218.1 - 2.9e-11 43.3 0.1 0.00069 20.0 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EKX42218.1 - 3.4e-11 43.1 0.1 4.6e-07 30.0 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX42218.1 - 3.1e-10 39.4 0.0 0.00025 21.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat cNMP_binding PF00027.29 EKX42219.1 - 5.4e-09 36.0 0.0 1.4e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain C2 PF00168.30 EKX42219.1 - 0.0088 16.3 0.1 0.021 15.1 0.1 1.6 1 0 0 1 1 1 1 C2 domain PACT_coil_coil PF10495.9 EKX42219.1 - 0.42 11.2 2.2 2.1 9.0 0.3 3.2 3 0 0 3 3 3 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein AAA PF00004.29 EKX42220.1 - 6.3e-09 36.3 0.0 1.3e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 EKX42220.1 - 4.3e-05 23.6 0.0 8.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 BCS1 N terminal LNS2 PF08235.13 EKX42221.1 - 2.4e-64 216.9 0.0 2.7e-64 216.8 0.0 1.0 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) DUF4831 PF16115.5 EKX42221.1 - 0.039 13.0 0.0 0.05 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4831) Hydrolase_6 PF13344.6 EKX42221.1 - 0.052 13.7 0.0 0.096 12.8 0.0 1.4 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 EKX42221.1 - 0.13 11.8 0.1 0.23 10.9 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2608) MTS PF05175.14 EKX42223.1 - 3e-15 56.2 0.0 4.8e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EKX42223.1 - 3.9e-10 40.3 0.0 7.5e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EKX42223.1 - 1.2e-09 38.0 0.0 1.7e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EKX42223.1 - 4e-09 36.4 0.0 4.6e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX42223.1 - 9e-06 25.6 0.0 5e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 EKX42223.1 - 0.00011 22.0 0.0 0.00017 21.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_11 PF08241.12 EKX42223.1 - 0.00038 21.0 0.0 0.00073 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EKX42223.1 - 0.0014 18.4 0.0 0.0021 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 EKX42223.1 - 0.0056 16.4 0.0 0.0087 15.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 EKX42223.1 - 0.0065 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 DUF43 PF01861.16 EKX42223.1 - 0.04 13.1 0.0 0.053 12.7 0.0 1.1 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain DUF4105 PF13387.6 EKX42223.1 - 0.064 12.9 0.0 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4105) Methyltransf_10 PF05971.12 EKX42223.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.3 1 1 0 1 1 1 0 RNA methyltransferase UPF0020 PF01170.18 EKX42223.1 - 0.23 11.1 0.2 2.1 8.0 0.0 2.1 1 1 1 2 2 2 0 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.18 EKX42223.1 - 0.24 10.7 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family EF-hand_6 PF13405.6 EKX42224.1 - 6.1e-14 50.7 2.4 1.1e-06 28.1 0.1 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 EKX42224.1 - 8.2e-14 51.8 2.9 1.1e-07 32.2 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX42224.1 - 4.9e-13 47.6 8.7 7.8e-06 25.1 0.2 3.9 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 EKX42224.1 - 3.9e-12 45.8 1.5 0.0005 19.9 0.2 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 EKX42224.1 - 0.00023 21.4 0.1 0.42 11.0 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain EF-hand_14 PF17959.1 EKX42224.1 - 0.0025 18.1 0.3 1.2 9.5 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EKX42224.1 - 0.0067 15.9 0.3 0.0067 15.9 0.3 3.9 5 0 0 5 5 5 1 EF hand p25-alpha PF05517.12 EKX42224.1 - 0.068 13.3 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 p25-alpha Ion_trans PF00520.31 EKX42225.1 - 1.2e-87 293.2 55.8 4.8e-49 166.8 19.8 2.0 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 EKX42225.1 - 9.7e-15 54.2 45.8 9.9e-10 37.7 9.0 5.6 3 2 2 5 5 5 4 Polycystin cation channel YvrJ PF12841.7 EKX42225.1 - 0.049 13.2 0.0 1.4 8.5 0.0 2.9 2 0 0 2 2 2 0 YvrJ protein family zf-RING_2 PF13639.6 EKX42226.1 - 1.6e-11 44.3 9.1 2.4e-11 43.8 9.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EKX42226.1 - 1e-08 35.0 0.7 1e-08 35.0 0.7 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EKX42226.1 - 1.3e-08 34.5 6.2 1.9e-08 34.0 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EKX42226.1 - 5.4e-08 32.6 8.7 1.4e-07 31.3 8.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX42226.1 - 6.4e-08 32.8 11.0 1.9e-07 31.2 11.0 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EKX42226.1 - 2.4e-06 27.3 7.7 4.2e-06 26.5 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX42226.1 - 7.3e-06 25.9 9.2 1e-05 25.4 9.2 1.2 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EKX42226.1 - 3.5e-05 23.6 7.1 5.6e-05 22.9 7.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EKX42226.1 - 0.00079 19.1 3.9 0.00079 19.1 3.9 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_4 PF14570.6 EKX42226.1 - 0.0018 18.0 5.5 0.0026 17.5 5.5 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 EKX42226.1 - 0.0028 17.7 3.2 0.0037 17.3 3.2 1.3 1 0 0 1 1 1 1 Zinc-binding RING-finger Zn_ribbon_17 PF17120.5 EKX42226.1 - 0.0052 16.4 11.6 0.0079 15.8 10.6 1.8 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type FYVE PF01363.21 EKX42226.1 - 0.007 16.5 11.0 0.028 14.5 11.0 1.8 1 1 0 1 1 1 1 FYVE zinc finger zf-RING_6 PF14835.6 EKX42226.1 - 0.01 15.7 2.4 0.015 15.1 2.4 1.4 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 EKX42226.1 - 0.015 15.3 7.4 0.037 14.1 7.4 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn-ribbon_8 PF09723.10 EKX42226.1 - 0.017 15.2 2.2 0.017 15.2 2.2 1.8 1 1 0 1 1 1 0 Zinc ribbon domain zf-C3HC4_4 PF15227.6 EKX42226.1 - 0.024 14.8 9.2 0.53 10.5 9.5 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Nudix_N_2 PF14803.6 EKX42226.1 - 0.03 14.2 3.0 4.4 7.3 0.3 2.5 2 0 0 2 2 2 0 Nudix N-terminal zf-Nse PF11789.8 EKX42226.1 - 0.04 13.8 2.3 0.08 12.8 2.3 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zinc_ribbon_16 PF17034.5 EKX42226.1 - 0.047 13.9 4.7 0.059 13.6 4.7 1.2 1 0 0 1 1 1 0 Zinc-ribbon like family RINGv PF12906.7 EKX42226.1 - 0.062 13.4 11.9 0.1 12.8 11.9 1.3 1 0 0 1 1 1 0 RING-variant domain FYVE_2 PF02318.16 EKX42226.1 - 0.073 13.3 5.7 0.09 13.0 5.7 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger DUF2318 PF10080.9 EKX42226.1 - 0.091 12.9 5.1 0.16 12.1 1.6 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) FANCL_C PF11793.8 EKX42226.1 - 0.12 12.6 10.0 0.19 11.9 5.6 2.1 1 1 1 2 2 2 0 FANCL C-terminal domain Rtf2 PF04641.12 EKX42226.1 - 0.14 11.5 2.4 0.15 11.4 2.4 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Zn_Tnp_IS91 PF14319.6 EKX42226.1 - 0.44 10.6 8.6 0.77 9.8 8.6 1.5 1 1 0 1 1 1 0 Transposase zinc-binding domain zf-Dof PF02701.15 EKX42226.1 - 2.1 8.6 8.3 0.34 11.1 1.1 2.3 2 1 0 2 2 2 0 Dof domain, zinc finger IBR PF01485.21 EKX42226.1 - 4.8 7.5 11.4 30 4.9 1.2 2.8 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Hint PF01079.20 EKX42227.1 - 3.2e-08 33.3 0.0 4.8e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Hint module D-ser_dehydrat PF14031.6 EKX42227.1 - 0.094 13.4 0.3 0.28 11.9 0.0 2.0 2 0 0 2 2 2 0 Putative serine dehydratase domain LRR_6 PF13516.6 EKX42228.1 - 7.8e-12 44.2 18.5 0.065 13.3 0.0 9.3 12 0 0 12 12 12 4 Leucine Rich repeat LRR_4 PF12799.7 EKX42228.1 - 5.3e-07 29.9 5.5 1.9 9.0 0.0 6.6 3 2 5 8 8 8 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX42228.1 - 0.0022 18.3 20.8 0.53 11.0 0.1 9.8 10 2 0 10 10 10 1 Leucine Rich Repeat Rhodanese PF00581.20 EKX42229.1 - 3.1e-11 43.8 0.0 4.1e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain PAS_10 PF13596.6 EKX42229.1 - 0.15 12.7 0.0 0.22 12.1 0.0 1.2 1 0 0 1 1 1 0 PAS domain Pannexin_like PF12534.8 EKX42231.1 - 8 5.4 9.3 10 5.1 9.3 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Rad51 PF08423.11 EKX42232.1 - 1.2e-12 47.6 0.0 4.8e-08 32.6 0.0 2.1 2 0 0 2 2 2 2 Rad51 AAA_25 PF13481.6 EKX42232.1 - 0.071 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cu-oxidase_2 PF07731.14 EKX42233.1 - 3.3e-24 85.2 0.5 5.5e-21 74.7 0.1 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EKX42233.1 - 4.1e-17 62.3 0.7 3.1e-15 56.2 0.1 2.8 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 EKX42233.1 - 1.6e-13 51.1 0.0 2.3e-09 37.6 0.0 3.0 3 1 0 3 3 3 2 Multicopper oxidase zf-C3HC4_3 PF13920.6 EKX42236.1 - 3.3e-13 49.3 12.6 3.3e-13 49.3 12.6 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX42236.1 - 7e-06 25.8 12.2 7e-06 25.8 12.2 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EKX42236.1 - 0.0011 19.2 15.1 0.0011 19.2 15.1 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 EKX42236.1 - 0.0052 16.7 13.2 0.0052 16.7 13.2 1.8 2 0 0 2 2 2 1 zinc-RING finger domain DUF4428 PF14471.6 EKX42236.1 - 2.7 8.0 9.4 0.15 12.0 4.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) Filamin PF00630.19 EKX42238.1 - 0.00052 20.8 0.0 0.0025 18.6 0.0 2.0 1 1 0 1 1 1 1 Filamin/ABP280 repeat ChitinaseA_N PF08329.10 EKX42238.1 - 0.16 11.6 0.1 0.5 10.0 0.1 1.8 1 1 1 2 2 2 0 Chitinase A, N-terminal domain SAM_1 PF00536.30 EKX42239.1 - 0.024 15.1 0.0 0.11 13.0 0.0 1.9 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) TTL PF03133.15 EKX42240.1 - 6.2e-18 64.9 0.0 1.2e-15 57.5 0.0 2.3 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family MIOX PF05153.15 EKX42240.1 - 0.12 11.9 0.0 2.6 7.5 0.0 2.1 2 0 0 2 2 2 0 Myo-inositol oxygenase Flavin_Reduct PF01613.18 EKX42241.1 - 0.0025 17.9 0.0 0.0029 17.7 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain XylR_N PF06505.11 EKX42241.1 - 0.0046 16.7 0.0 0.0066 16.2 0.0 1.2 1 0 0 1 1 1 1 Activator of aromatic catabolism WD40 PF00400.32 EKX42242.1 - 2e-38 129.7 12.9 1.7e-07 31.8 0.1 7.1 6 1 1 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX42242.1 - 5.2e-18 65.1 1.8 0.00043 20.5 0.0 6.0 1 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EKX42242.1 - 2.5e-06 27.5 0.0 0.021 14.7 0.0 3.5 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 EKX42242.1 - 1.3e-05 24.5 0.0 9.1e-05 21.7 0.0 1.9 1 1 1 2 2 2 1 Coatomer WD associated region WD40_like PF17005.5 EKX42242.1 - 3.3e-05 23.4 0.0 2.5 7.3 0.0 3.8 3 2 0 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 EKX42242.1 - 3.9e-05 22.8 0.3 0.39 9.6 0.0 3.9 2 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 EKX42242.1 - 0.0011 17.4 0.1 0.1 10.9 0.0 3.0 1 1 2 4 4 4 2 WD repeat-containing and planar cell polarity effector protein Fritz VID27 PF08553.10 EKX42242.1 - 0.011 14.9 0.1 0.66 9.0 0.0 2.7 1 1 2 3 3 3 0 VID27 C-terminal WD40-like domain RAB3GAP2_N PF14655.6 EKX42242.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Cytochrom_D1 PF02239.16 EKX42242.1 - 0.016 13.7 0.3 2.1 6.8 0.0 3.2 1 1 3 4 4 4 0 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 EKX42242.1 - 0.053 12.3 1.2 14 4.3 0.0 3.9 1 1 0 3 3 3 0 Nup133 N terminal like PQQ PF01011.21 EKX42242.1 - 0.059 13.3 0.1 1.9 8.6 0.0 2.7 2 0 0 2 2 2 0 PQQ enzyme repeat BBS2_N PF14781.6 EKX42242.1 - 0.11 12.5 0.0 0.84 9.6 0.0 2.3 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal IKI3 PF04762.12 EKX42242.1 - 0.12 10.3 1.4 2.4 6.1 0.0 2.8 2 1 0 3 3 3 0 IKI3 family FlxA PF14282.6 EKX42243.1 - 0.029 14.4 11.5 0.094 12.7 11.5 1.9 1 0 0 1 1 1 0 FlxA-like protein PDZ_6 PF17820.1 EKX42244.1 - 0.00062 19.6 0.0 0.002 17.9 0.0 1.9 1 0 0 1 1 1 1 PDZ domain TSP_3 PF02412.18 EKX42244.1 - 0.0024 17.5 4.5 0.0024 17.5 4.5 34.1 14 7 20 35 35 35 17 Thrombospondin type 3 repeat DUF4148 PF13663.6 EKX42244.1 - 2.5 8.4 7.8 8.3 6.7 1.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) DUF3342 PF11822.8 EKX42245.1 - 8.6e-19 67.5 0.1 1.8e-18 66.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) CHORD PF04968.12 EKX42245.1 - 0.046 14.5 7.5 0.16 12.7 7.5 2.0 1 0 0 1 1 1 0 CHORD RecR PF02132.15 EKX42245.1 - 0.12 12.0 3.8 0.067 12.8 0.8 2.1 2 0 0 2 2 2 0 RecR protein zf-C2HC5 PF06221.13 EKX42245.1 - 0.33 11.0 3.6 2.8 8.0 0.4 2.6 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type C1_1 PF00130.22 EKX42245.1 - 3.5 7.6 7.7 14 5.6 0.3 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OST-HTH PF12872.7 EKX42248.1 - 0.11 12.3 0.0 0.33 10.8 0.0 1.8 1 0 0 1 1 1 0 OST-HTH/LOTUS domain Pyr_redox_2 PF07992.14 EKX42250.1 - 4.7e-70 236.1 1.5 7.7e-70 235.4 1.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EKX42250.1 - 2.9e-39 133.7 0.5 7.5e-39 132.4 0.5 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EKX42250.1 - 6.9e-21 74.6 4.9 2.5e-17 63.2 0.1 3.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EKX42250.1 - 1.1e-10 41.5 1.9 2e-10 40.6 0.4 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EKX42250.1 - 1.8e-09 37.3 4.0 1.4e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EKX42250.1 - 5.2e-09 35.7 7.4 2.4e-06 26.9 6.1 2.8 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EKX42250.1 - 1.7e-07 30.7 11.0 8.3e-07 28.4 2.6 3.7 4 0 0 4 4 4 1 FAD binding domain NAD_binding_8 PF13450.6 EKX42250.1 - 2.8e-07 30.7 1.8 0.00029 21.0 0.4 3.1 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 EKX42250.1 - 3.4e-06 26.5 5.0 0.011 15.1 0.0 3.5 3 1 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EKX42250.1 - 1.9e-05 24.1 5.4 0.0051 16.1 0.5 2.5 2 1 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 EKX42250.1 - 9.3e-05 21.3 10.9 0.00029 19.7 1.5 3.5 3 1 1 4 4 4 2 HI0933-like protein Thi4 PF01946.17 EKX42250.1 - 0.00013 21.3 1.3 0.00051 19.3 0.2 2.2 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 EKX42250.1 - 0.0002 20.6 0.0 0.008 15.4 0.0 2.4 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) UDPG_MGDP_dh_N PF03721.14 EKX42250.1 - 0.001 18.7 1.8 0.011 15.4 0.0 2.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 EKX42250.1 - 0.0054 16.6 0.1 0.0054 16.6 0.1 2.9 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 EKX42250.1 - 0.011 15.4 5.7 0.35 10.4 0.2 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EKX42250.1 - 0.041 12.9 2.0 3.3 6.6 1.2 2.5 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 EKX42250.1 - 0.099 13.1 1.9 1.9 9.0 0.0 3.1 3 0 0 3 3 3 0 Putative NAD(P)-binding PPR_2 PF13041.6 EKX42251.1 - 6.9e-32 109.4 23.1 0.00059 20.0 0.0 13.5 9 3 5 14 14 14 9 PPR repeat family PPR_3 PF13812.6 EKX42251.1 - 1.3e-30 105.3 8.0 9.4e-10 38.4 0.1 10.7 10 2 0 10 10 10 4 Pentatricopeptide repeat domain PPR_long PF17177.4 EKX42251.1 - 1.3e-11 44.3 9.7 0.0016 17.9 0.4 5.5 2 1 3 5 5 5 4 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EKX42251.1 - 9.7e-09 34.8 15.8 0.19 11.4 0.0 10.1 11 0 0 11 11 11 3 PPR repeat ECSIT PF06239.11 EKX42251.1 - 0.0012 18.1 2.6 5.2 6.1 0.1 5.8 5 1 1 6 6 6 1 Evolutionarily conserved signalling intermediate in Toll pathway BKACE PF05853.12 EKX42251.1 - 0.015 14.6 1.5 1.6 8.0 0.1 3.7 2 1 1 4 4 4 0 beta-keto acid cleavage enzyme Exog_C PF18026.1 EKX42251.1 - 0.019 15.0 0.1 30 4.8 0.0 5.4 6 0 0 6 6 6 0 Endo/exonuclease (EXOG) C-terminal domain Cas_Cas02710 PF09670.10 EKX42251.1 - 0.068 12.0 0.6 2.7 6.7 0.0 2.6 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_Cas02710) aGPT-Pplase1 PF18723.1 EKX42251.1 - 0.2 11.0 1.1 2.6 7.4 0.0 2.7 2 1 1 3 3 3 0 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 Caprin-1_dimer PF18293.1 EKX42251.1 - 1.2 9.6 3.8 9.7 6.7 0.2 3.9 3 1 2 5 5 5 0 Caprin-1 dimerization domain Ank_4 PF13637.6 EKX42253.1 - 2.6e-15 56.6 0.3 5.7e-07 30.0 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX42253.1 - 1.6e-11 44.1 0.1 3.4e-05 24.1 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EKX42253.1 - 5.6e-11 41.7 0.3 0.84 10.4 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 EKX42253.1 - 1.7e-10 41.4 0.0 1e-09 38.8 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX42253.1 - 4.1e-08 33.3 0.7 0.0054 17.0 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) LRR_8 PF13855.6 EKX42255.1 - 2e-62 206.8 67.5 7.1e-10 38.5 0.7 11.0 3 2 9 13 13 13 13 Leucine rich repeat LRR_4 PF12799.7 EKX42255.1 - 1.5e-60 200.0 72.4 1.4e-07 31.7 0.1 14.4 4 4 11 18 18 18 18 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX42255.1 - 1.6e-13 49.1 66.2 5.8 7.9 0.0 20.0 21 1 1 22 22 22 5 Leucine Rich Repeat LRR_9 PF14580.6 EKX42255.1 - 1.8e-10 40.6 37.3 0.07 12.6 2.7 7.3 2 2 5 7 7 7 7 Leucine-rich repeat LRR_6 PF13516.6 EKX42255.1 - 0.0092 16.0 72.1 2.1 8.6 0.1 16.4 18 0 0 18 18 18 5 Leucine Rich repeat LRR_5 PF13306.6 EKX42255.1 - 0.035 14.1 6.4 7.1 6.6 0.0 4.9 2 2 1 5 5 5 0 BspA type Leucine rich repeat region (6 copies) PQQ_3 PF13570.6 EKX42256.1 - 6e-17 61.6 5.6 0.00084 19.7 0.0 5.4 5 0 0 5 5 5 4 PQQ-like domain PQQ PF01011.21 EKX42256.1 - 4.9e-13 48.3 0.7 3.2e-05 23.6 0.0 3.8 3 0 0 3 3 3 3 PQQ enzyme repeat PQQ_2 PF13360.6 EKX42256.1 - 1.1e-11 44.8 0.0 7.5e-06 25.7 0.0 2.1 1 1 1 2 2 2 2 PQQ-like domain V1R PF03402.14 EKX42258.1 - 0.088 12.4 1.5 0.11 12.2 0.4 1.8 1 1 0 1 1 1 0 Vomeronasal organ pheromone receptor family, V1R MgtE PF01769.16 EKX42258.1 - 0.15 12.4 8.5 0.42 11.0 1.3 2.1 1 1 1 2 2 2 0 Divalent cation transporter Rhodanese PF00581.20 EKX42259.1 - 5.1e-07 30.2 0.0 9e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Arm PF00514.23 EKX42260.1 - 7.9e-06 25.7 1.2 0.74 9.9 0.3 3.5 3 0 0 3 3 3 3 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EKX42260.1 - 0.031 14.3 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain CDC14 PF08045.11 EKX42260.1 - 0.039 13.0 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 Cell division control protein 14, SIN component Response_reg PF00072.24 EKX42261.1 - 1e-32 112.6 3.3 6.5e-17 61.7 0.6 3.0 2 1 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 EKX42261.1 - 1.6e-07 31.8 0.0 9.5e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 EKX42261.1 - 1.7e-06 28.2 0.1 0.00036 20.7 0.0 2.9 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 EKX42261.1 - 2.6e-05 24.1 0.0 0.034 14.2 0.0 2.6 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 EKX42261.1 - 0.00095 19.4 0.0 0.011 16.0 0.0 2.4 2 0 0 2 2 2 1 PAS fold HisKA PF00512.25 EKX42261.1 - 0.026 14.6 0.0 0.062 13.3 0.0 1.7 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain RA PF00788.23 EKX42261.1 - 0.04 14.6 0.0 0.49 11.0 0.0 2.4 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain Pkinase PF00069.25 EKX42262.1 - 1.4e-29 103.3 0.0 1.5e-29 103.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX42262.1 - 5.5e-22 78.3 0.0 6.3e-22 78.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Prp18 PF02840.15 EKX42262.1 - 0.018 15.1 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 Prp18 domain Kdo PF06293.14 EKX42262.1 - 0.055 12.8 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX42262.1 - 0.079 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family U-box PF04564.15 EKX42263.1 - 2.2e-15 56.6 0.0 2.9e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX42263.1 - 6.9e-05 22.6 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 EKX42263.1 - 0.11 12.7 0.1 0.31 11.3 0.1 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain Pkinase_Tyr PF07714.17 EKX42264.1 - 6e-21 74.9 0.0 6.4e-21 74.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX42264.1 - 3e-17 62.9 0.0 3.2e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain PBP_like_2 PF12849.7 EKX42265.1 - 5e-12 46.1 0.0 5.5e-12 45.9 0.0 1.0 1 0 0 1 1 1 1 PBP superfamily domain PAP2 PF01569.21 EKX42266.1 - 7.1e-08 32.3 4.1 7.1e-08 32.3 4.1 2.2 3 0 0 3 3 3 1 PAP2 superfamily Hydrolase_4 PF12146.8 EKX42267.1 - 1.3e-16 60.6 0.0 2.2e-13 50.0 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EKX42267.1 - 4.3e-08 33.1 0.2 5.4e-06 26.2 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EKX42267.1 - 5.9e-07 30.3 0.0 9.2e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 EKX42267.1 - 3.8e-05 23.4 0.0 7.2e-05 22.5 0.0 1.3 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 EKX42267.1 - 0.00021 21.3 0.0 0.013 15.4 0.0 2.1 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 EKX42267.1 - 0.00025 20.6 0.0 0.00039 19.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 EKX42267.1 - 0.0016 18.0 0.0 4.7 6.7 0.0 2.9 3 0 0 3 3 3 2 Dienelactone hydrolase family FSH1 PF03959.13 EKX42267.1 - 0.0043 16.7 0.0 0.0085 15.8 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) PGAP1 PF07819.13 EKX42267.1 - 0.0082 15.9 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 1 PGAP1-like protein Esterase PF00756.20 EKX42267.1 - 0.024 14.3 0.0 0.09 12.4 0.0 1.8 2 0 0 2 2 2 0 Putative esterase LIP PF03583.14 EKX42267.1 - 0.24 10.7 0.2 36 3.6 0.1 2.9 1 1 2 3 3 3 0 Secretory lipase Aconitase_2_N PF06434.13 EKX42268.1 - 5.7e-97 323.3 0.0 1e-96 322.5 0.0 1.4 1 0 0 1 1 1 1 Aconitate hydratase 2 N-terminus Aconitase_B_N PF11791.8 EKX42268.1 - 3.2e-64 215.7 0.1 5.1e-64 215.0 0.1 1.3 1 0 0 1 1 1 1 Aconitate B N-terminal domain Aconitase PF00330.20 EKX42268.1 - 6.2e-43 147.5 0.0 3.7e-41 141.6 0.0 2.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) PI-TkoII_IV PF18714.1 EKX42268.1 - 0.076 12.5 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV CRAL_TRIO PF00650.20 EKX42269.1 - 5.3e-32 110.7 0.0 6.9e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EKX42269.1 - 0.13 12.4 0.1 0.34 11.1 0.1 1.7 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain AAA_18 PF13238.6 EKX42269.1 - 0.17 12.4 0.0 0.27 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 EKX42270.1 - 4.7e-56 190.1 0.0 5.4e-56 189.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX42270.1 - 1e-42 146.2 0.0 1.2e-42 146.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX42270.1 - 0.00028 19.8 0.0 0.00037 19.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EKX42270.1 - 0.25 10.6 0.1 3 7.1 0.1 2.4 2 1 0 2 2 2 0 Kinase-like NHL PF01436.21 EKX42271.1 - 2.3e-05 24.2 0.1 8.8e-05 22.4 0.0 2.1 2 1 0 2 2 2 1 NHL repeat Arylesterase PF01731.20 EKX42271.1 - 0.0053 16.9 0.0 0.0093 16.1 0.0 1.4 1 0 0 1 1 1 1 Arylesterase Ion_trans PF00520.31 EKX42273.1 - 1.4e-19 70.3 10.2 1.4e-19 70.3 10.2 2.1 2 1 0 2 2 2 1 Ion transport protein PH PF00169.29 EKX42273.1 - 2.2e-08 34.5 2.4 1.4e-06 28.7 0.1 3.1 3 1 1 4 4 4 1 PH domain PKD_channel PF08016.12 EKX42273.1 - 5.5e-05 22.0 1.1 5.5e-05 22.0 1.1 1.9 2 0 0 2 2 2 1 Polycystin cation channel EF-hand_6 PF13405.6 EKX42273.1 - 0.00032 20.4 0.0 0.00094 18.9 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 EKX42273.1 - 0.00061 19.2 0.0 0.0017 17.8 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EKX42273.1 - 0.0022 18.4 0.3 0.0057 17.1 0.3 1.7 1 0 0 1 1 1 1 EF-hand domain pair F420H2_quin_red PF04075.14 EKX42274.1 - 0.23 11.6 0.0 0.23 11.6 0.0 1.1 1 0 0 1 1 1 0 F420H(2)-dependent quinone reductase RCC1_2 PF13540.6 EKX42275.1 - 4.1e-36 122.0 32.8 4.2e-10 39.2 3.7 6.3 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EKX42275.1 - 3.9e-15 56.2 26.7 0.00033 21.2 0.1 7.2 6 1 1 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Gtr1_RagA PF04670.12 EKX42276.1 - 1.1e-58 198.4 1.7 1.7e-58 197.7 1.7 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 EKX42276.1 - 2.9e-06 26.9 0.0 6.9e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EKX42276.1 - 7.4e-06 26.2 0.0 1.4e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EKX42276.1 - 0.00084 19.4 0.0 0.0028 17.7 0.0 1.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase SRPRB PF09439.10 EKX42276.1 - 0.0011 18.4 0.3 0.0028 17.1 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EKX42276.1 - 0.013 15.9 0.0 0.029 14.7 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain Ras PF00071.22 EKX42276.1 - 0.013 15.1 0.2 0.34 10.5 0.0 2.1 1 1 1 2 2 2 0 Ras family AAA_14 PF13173.6 EKX42276.1 - 0.059 13.4 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EKX42277.1 - 3.3e-26 93.0 12.0 3.3e-26 93.0 12.0 8.2 1 1 4 5 5 1 1 AAA domain AAA_15 PF13175.6 EKX42277.1 - 7.4e-10 39.1 11.6 7.4e-10 39.1 11.6 4.8 1 1 3 4 4 2 2 AAA ATPase domain AAA_21 PF13304.6 EKX42277.1 - 2.1e-09 37.6 9.3 0.00012 22.0 0.0 3.8 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EKX42277.1 - 6.1e-07 29.1 0.1 6.1e-07 29.1 0.1 3.4 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EKX42277.1 - 3.6e-05 23.9 0.0 0.00011 22.3 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 EKX42277.1 - 0.0012 19.3 0.1 0.0012 19.3 0.1 7.5 4 3 0 4 4 2 1 ABC transporter AAA_29 PF13555.6 EKX42277.1 - 0.0015 18.2 0.0 0.0033 17.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.6 EKX42277.1 - 0.011 14.5 0.4 0.011 14.5 0.4 7.1 1 1 5 6 6 5 0 AAA domain AAA_16 PF13191.6 EKX42277.1 - 0.022 15.2 0.9 0.21 11.9 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain zf-3CxxC_2 PF17180.4 EKX42277.1 - 0.061 14.1 1.3 2.9 8.7 0.9 4.0 2 0 0 2 2 2 0 Zinc-binding domain phage_tail_N PF08400.10 EKX42277.1 - 0.13 12.3 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Prophage tail fibre N-terminal Homeobox_KN PF05920.11 EKX42278.1 - 1e-18 66.9 0.1 1.2e-18 66.7 0.1 1.1 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EKX42278.1 - 3.3e-06 26.8 0.0 3.5e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 EKX42278.1 - 0.0078 15.7 0.1 0.098 12.1 0.0 2.0 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez Redoxin PF08534.10 EKX42278.1 - 0.18 11.5 0.0 0.18 11.5 0.0 1.0 1 0 0 1 1 1 0 Redoxin CBFD_NFYB_HMF PF00808.23 EKX42279.1 - 5.1e-08 33.1 0.0 9e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ank_2 PF12796.7 EKX42281.1 - 1.8e-08 34.8 0.0 0.011 16.3 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) PKD_channel PF08016.12 EKX42281.1 - 7.5e-06 24.9 9.7 1.1e-05 24.3 9.7 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 EKX42281.1 - 2.8e-05 23.5 15.3 4.6e-05 22.8 15.3 1.4 1 1 0 1 1 1 1 Ion transport protein Ank_3 PF13606.6 EKX42281.1 - 0.00015 21.9 0.4 0.61 10.8 0.0 5.4 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 EKX42281.1 - 0.00024 21.4 0.0 10 6.6 0.0 4.7 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX42281.1 - 0.00054 20.3 0.2 1.4 9.5 0.0 4.5 5 0 0 5 5 5 1 Ankyrin repeat Spc7 PF08317.11 EKX42284.1 - 0.00087 18.3 1.4 0.00088 18.2 1.4 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 EKX42284.1 - 0.005 16.9 2.2 0.0052 16.8 2.2 1.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein HIP1_clath_bdg PF16515.5 EKX42284.1 - 0.0072 16.9 4.6 0.011 16.3 4.6 1.3 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1635 PF07795.11 EKX42284.1 - 0.017 15.0 1.9 0.018 14.9 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Ald_deCOase PF11266.8 EKX42284.1 - 0.023 14.4 0.1 0.027 14.2 0.1 1.1 1 0 0 1 1 1 0 Long-chain fatty aldehyde decarbonylase GlcNAc-1_reg PF18440.1 EKX42284.1 - 0.043 14.1 0.2 0.067 13.4 0.1 1.4 1 1 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain Spc24 PF08286.11 EKX42284.1 - 2.1 8.6 5.9 8.8 6.6 5.9 1.8 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 GBP_C PF02841.14 EKX42285.1 - 3.6 6.9 23.1 5.6 6.3 23.1 1.3 1 1 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF3438 PF11920.8 EKX42286.1 - 0.11 11.7 0.1 0.21 10.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) DUF4192 PF13830.6 EKX42286.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Kelch_1 PF01344.25 EKX42289.1 - 8.5e-38 127.7 5.4 4.3e-11 42.2 0.0 6.8 5 2 1 6 6 6 5 Kelch motif Kelch_6 PF13964.6 EKX42289.1 - 3.3e-23 81.1 0.5 3.9e-06 27.0 0.0 5.9 3 1 3 6 6 6 4 Kelch motif Kelch_4 PF13418.6 EKX42289.1 - 3.5e-15 55.7 0.0 0.00041 20.3 0.0 4.9 3 2 1 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.6 EKX42289.1 - 4e-13 49.3 0.2 0.0043 17.3 0.1 4.9 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 EKX42289.1 - 1.5e-12 46.9 2.9 0.004 17.1 0.0 5.7 4 1 1 5 5 5 3 Kelch motif Kelch_5 PF13854.6 EKX42289.1 - 3.2e-09 36.6 0.8 0.039 14.0 0.0 4.1 4 0 0 4 4 4 3 Kelch motif F-box-like PF12937.7 EKX42289.1 - 5.6e-07 29.4 0.9 1.5e-06 28.0 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EKX42289.1 - 0.00083 19.2 0.5 0.003 17.4 0.1 2.1 2 0 0 2 2 2 1 F-box domain Elongin_A PF06881.11 EKX42289.1 - 0.029 14.9 0.1 0.055 14.0 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Abhydrolase_6 PF12697.7 EKX42290.1 - 0.00015 22.4 0.5 0.00032 21.4 0.5 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EKX42290.1 - 0.0012 18.6 0.0 0.0047 16.6 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EKX42290.1 - 0.099 11.9 0.0 0.32 10.2 0.0 1.7 1 1 0 1 1 1 0 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 EKX42290.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase FtsX PF02687.21 EKX42290.1 - 4.5 7.8 6.9 8.4 6.9 0.3 3.0 2 0 0 2 2 2 0 FtsX-like permease family MPP6 PF10175.9 EKX42290.1 - 7.1 7.1 9.3 0.35 11.4 1.1 2.1 2 0 0 2 2 2 0 M-phase phosphoprotein 6 Pkinase PF00069.25 EKX42291.1 - 5.7e-78 261.9 0.3 8.5e-78 261.3 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX42291.1 - 1.4e-44 152.3 0.0 2e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 EKX42291.1 - 6.4e-25 87.4 13.2 4.2e-12 46.3 1.7 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX42291.1 - 5.2e-21 72.6 9.7 6.4e-06 25.4 0.2 4.8 5 0 0 5 5 4 4 EF hand EF-hand_8 PF13833.6 EKX42291.1 - 6.1e-19 67.6 6.0 1.2e-09 37.9 0.2 3.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX42291.1 - 2.1e-17 61.5 5.1 0.0005 19.8 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_9 PF14658.6 EKX42291.1 - 4.1e-13 49.5 0.4 2.8e-06 27.5 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain Kinase-like PF14531.6 EKX42291.1 - 1e-08 34.8 0.1 3.9e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like EF-hand_5 PF13202.6 EKX42291.1 - 3.8e-07 29.3 4.1 0.00071 19.0 0.1 4.5 4 0 0 4 4 4 1 EF hand SPARC_Ca_bdg PF10591.9 EKX42291.1 - 5.4e-07 29.9 1.4 0.24 11.7 0.0 3.3 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Pkinase_fungal PF17667.1 EKX42291.1 - 2.2e-06 26.8 1.4 2.7e-05 23.1 0.0 2.7 2 1 0 3 3 3 1 Fungal protein kinase Kdo PF06293.14 EKX42291.1 - 8e-05 22.1 0.3 0.00018 20.9 0.3 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 EKX42291.1 - 0.0006 20.0 0.1 0.0016 18.6 0.1 1.7 1 0 0 1 1 1 1 ABC1 family EF-hand_14 PF17959.1 EKX42291.1 - 0.0018 18.6 3.8 0.05 14.0 0.2 3.4 4 0 0 4 4 3 1 EF-hand domain EF-hand_4 PF12763.7 EKX42291.1 - 0.0085 16.0 2.5 0.85 9.6 0.1 2.7 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand APH PF01636.23 EKX42291.1 - 0.061 13.2 0.2 5.9 6.7 0.0 3.3 3 1 1 4 4 4 0 Phosphotransferase enzyme family EF-hand_10 PF14788.6 EKX42291.1 - 0.093 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 EF hand RIO1 PF01163.22 EKX42291.1 - 0.13 11.8 3.2 0.84 9.2 3.2 2.0 1 1 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 EKX42291.1 - 0.19 11.2 2.3 0.29 10.6 0.1 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL EF-hand_11 PF08976.11 EKX42291.1 - 0.19 12.6 0.4 10 7.1 0.0 2.9 3 0 0 3 3 2 0 EF-hand domain Beta_helix PF13229.6 EKX42292.1 - 0.03 14.2 0.0 0.048 13.5 0.0 1.2 1 0 0 1 1 1 0 Right handed beta helix region Radial_spoke PF04712.12 EKX42292.1 - 3.4 6.5 14.8 13 4.6 10.3 2.3 2 0 0 2 2 2 0 Radial spokehead-like protein eIF-3c_N PF05470.12 EKX42292.1 - 3.6 5.8 8.2 6.8 4.9 8.2 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2201_N PF13203.6 EKX42292.1 - 5.5 6.5 11.9 1 8.9 6.1 2.3 2 0 0 2 2 2 0 Putative metallopeptidase domain BSP_II PF05432.11 EKX42292.1 - 8.5 6.0 26.3 1.1 8.9 18.2 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Methyltransf_32 PF13679.6 EKX42293.1 - 5.5e-18 65.5 0.8 1.8e-17 63.8 0.8 1.8 1 1 0 1 1 1 1 Methyltransferase domain SAM_3 PF18016.1 EKX42293.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) 14-3-3 PF00244.20 EKX42294.1 - 1.3e-83 279.9 6.9 1.5e-83 279.7 6.9 1.0 1 0 0 1 1 1 1 14-3-3 protein HBM PF16591.5 EKX42294.1 - 0.061 12.7 0.2 0.061 12.7 0.2 2.0 2 0 0 2 2 2 0 Helical bimodular sensor domain HTH_38 PF13936.6 EKX42294.1 - 0.11 12.3 0.1 0.35 10.7 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Ins134_P3_kin PF05770.11 EKX42295.1 - 2.9e-26 92.2 1.4 1.8e-16 60.3 0.0 2.1 1 1 1 2 2 2 2 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain PcF PF09461.10 EKX42295.1 - 0.098 13.0 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 Phytotoxin PcF protein He_PIG PF05345.12 EKX42296.1 - 5.8e-09 36.0 10.4 1.1e-06 28.8 1.2 3.1 3 0 0 3 3 3 2 Putative Ig domain C2 PF00168.30 EKX42296.1 - 0.00062 20.0 0.0 0.007 16.6 0.0 2.4 1 1 0 1 1 1 1 C2 domain PDZ_6 PF17820.1 EKX42296.1 - 0.038 13.8 0.3 0.32 10.9 0.1 2.7 2 0 0 2 2 2 0 PDZ domain HSP90 PF00183.18 EKX42297.1 - 1.1e-150 503.1 1.9 2e-150 502.1 1.9 1.4 1 1 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.6 EKX42297.1 - 7.3e-14 51.8 0.9 1.6e-13 50.6 0.9 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EKX42297.1 - 4.9e-11 43.1 0.7 5e-10 39.9 0.2 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPOB_ab PF14682.6 EKX42297.1 - 0.14 12.2 1.0 0.34 11.0 0.1 2.0 2 0 0 2 2 2 0 Sporulation initiation phospho-transferase B, C-terminal UPF0547 PF10571.9 EKX42298.1 - 3.6e-08 33.3 4.1 6.8e-08 32.4 4.1 1.5 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 DZR PF12773.7 EKX42298.1 - 0.0074 16.3 1.5 0.014 15.4 1.5 1.4 1 0 0 1 1 1 1 Double zinc ribbon HLH PF00010.26 EKX42298.1 - 0.0085 16.0 10.9 0.062 13.3 0.1 3.0 3 0 0 3 3 3 2 Helix-loop-helix DNA-binding domain Roughex PF06020.11 EKX42298.1 - 0.9 8.6 8.8 1.9 7.5 8.8 1.4 1 0 0 1 1 1 0 Drosophila roughex protein CENP-H PF05837.12 EKX42298.1 - 0.98 9.8 6.9 2 8.9 0.0 3.4 2 1 1 3 3 3 0 Centromere protein H (CENP-H) zinc_ribbon_15 PF17032.5 EKX42298.1 - 3.3 8.5 5.3 0.24 12.2 0.3 1.7 2 0 0 2 2 2 0 zinc-ribbon family IHABP4_N PF16174.5 EKX42299.1 - 3.7 8.1 17.2 1.6 9.3 9.8 2.1 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Annexin_like PF18411.1 EKX42300.1 - 0.12 12.6 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 Annexin-like domain CBP4 PF07960.11 EKX42301.1 - 0.087 12.7 0.4 0.13 12.1 0.4 1.4 1 0 0 1 1 1 0 CBP4 MHYT PF03707.16 EKX42301.1 - 1.3 9.2 7.6 7.2 6.9 1.8 2.3 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat NIF3 PF01784.18 EKX42302.1 - 6.2e-59 199.6 0.0 7.7e-59 199.3 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) SCP2 PF02036.17 EKX42302.1 - 0.042 14.3 0.0 0.089 13.3 0.0 1.5 1 0 0 1 1 1 0 SCP-2 sterol transfer family RadC PF04002.15 EKX42302.1 - 0.12 12.3 0.0 1.3 9.0 0.0 2.1 2 0 0 2 2 2 0 RadC-like JAB domain Biotin_lipoyl PF00364.22 EKX42303.1 - 2.2e-18 65.8 0.8 3.4e-18 65.2 0.8 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme DEC-1_N PF04625.13 EKX42303.1 - 0.014 14.4 5.8 0.017 14.1 5.8 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region BOF PF04076.13 EKX42303.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial OB fold (BOF) protein DUF2057 PF09829.9 EKX42303.1 - 0.29 11.3 2.3 0.38 10.9 2.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) DUF3597 PF12200.8 EKX42303.1 - 0.96 10.0 5.7 1.8 9.1 5.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) NUDIX_2 PF13869.6 EKX42304.1 - 4.1e-71 238.5 0.0 5e-71 238.2 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase NUDIX PF00293.28 EKX42304.1 - 0.012 15.7 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 0 NUDIX domain Atx10homo_assoc PF09759.9 EKX42305.1 - 0.00024 21.1 4.3 0.0011 18.9 0.1 3.5 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 EKX42305.1 - 0.0082 16.2 16.1 2.3 8.4 0.3 6.3 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat ROKNT PF08067.11 EKX42307.1 - 0.2 12.0 2.0 3 8.2 0.0 3.0 3 0 0 3 3 3 0 ROKNT (NUC014) domain WD40 PF00400.32 EKX42308.1 - 5.5e-19 68.2 4.8 0.00014 22.5 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 EKX42308.1 - 1.1e-06 27.6 1.0 0.00056 18.7 0.1 2.9 1 1 1 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EKX42308.1 - 0.00017 21.8 0.0 4.4 7.7 0.0 3.5 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EKX42308.1 - 0.025 15.1 0.6 9.9 6.8 0.1 3.8 5 0 0 5 5 5 0 PQQ-like domain PALB2_WD40 PF16756.5 EKX42308.1 - 0.046 12.6 0.3 0.74 8.7 0.0 2.2 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain SprT-like PF10263.9 EKX42309.1 - 6.7e-24 83.9 0.1 1e-23 83.4 0.1 1.3 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 EKX42309.1 - 2e-09 37.2 4.6 3.7e-09 36.3 4.6 1.5 1 0 0 1 1 1 1 SprT-like zinc ribbon domain WLM PF08325.10 EKX42309.1 - 0.0059 16.7 0.3 0.028 14.5 0.0 1.9 2 0 0 2 2 2 1 WLM domain Zn-ribbon_8 PF09723.10 EKX42309.1 - 0.057 13.6 1.2 0.15 12.2 1.2 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Cytochrom_c3_2 PF14537.6 EKX42309.1 - 0.1 13.1 4.9 0.12 12.9 0.4 2.4 1 1 1 2 2 2 0 Cytochrome c3 Cytochrome_C7 PF14522.6 EKX42309.1 - 0.27 11.3 4.9 11 6.2 6.0 2.4 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c EF-hand_1 PF00036.32 EKX42310.1 - 9.9e-20 68.6 16.5 1e-05 24.7 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 EKX42310.1 - 7.1e-19 66.4 12.2 1.9e-05 24.0 1.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EKX42310.1 - 3.3e-16 59.5 12.3 1.2e-10 41.6 0.9 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 EKX42310.1 - 5.5e-15 54.9 11.9 1.2e-06 28.2 0.1 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EKX42310.1 - 3.3e-14 51.5 15.6 1.4e-05 24.6 0.4 4.3 4 0 0 4 4 4 4 EF-hand domain Caleosin PF05042.13 EKX42310.1 - 0.00023 21.1 0.7 0.41 10.6 0.0 3.2 2 2 2 4 4 4 2 Caleosin related protein SPARC_Ca_bdg PF10591.9 EKX42310.1 - 0.00061 20.1 2.5 0.11 12.8 0.2 2.9 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 EKX42310.1 - 0.001 19.9 0.2 0.0041 18.0 0.1 1.9 1 1 1 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 EKX42310.1 - 0.0012 19.0 0.4 12 6.1 0.0 3.5 4 0 0 4 4 4 1 Dockerin type I domain EF-hand_4 PF12763.7 EKX42310.1 - 0.0092 15.9 3.3 0.27 11.2 0.3 2.8 2 2 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand VCBS PF13517.6 EKX42310.1 - 0.088 13.4 3.5 7.9 7.2 0.1 3.1 3 1 1 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF4215 PF13948.6 EKX42311.1 - 7.6e-09 35.9 1.9 7.6e-09 35.9 1.9 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4215) ZU5 PF00791.20 EKX42311.1 - 0.0023 18.2 0.0 0.0049 17.2 0.0 1.5 1 0 0 1 1 1 1 ZU5 domain Defensin_1 PF00323.19 EKX42312.1 - 0.0016 19.0 14.3 7.5e+02 0.8 0.0 11.1 13 0 0 13 13 13 0 Mammalian defensin Peptidase_S49_N PF08496.10 EKX42312.1 - 0.066 13.3 0.7 22 5.1 0.0 5.2 1 1 12 13 13 13 0 Peptidase family S49 N-terminal PX PF00787.24 EKX42313.1 - 3.1e-15 56.1 0.0 4.8e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 PX domain Helicase_C_2 PF13307.6 EKX42314.1 - 1.1e-50 172.1 0.0 3.1e-50 170.7 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 EKX42314.1 - 1.4e-50 171.4 1.5 2.4e-50 170.6 1.5 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 EKX42314.1 - 0.0026 17.8 0.9 0.5 10.4 0.0 3.1 2 2 1 3 3 3 2 Type III restriction enzyme, res subunit DUF3783 PF12646.7 EKX42314.1 - 0.041 13.9 0.1 4.3 7.4 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) AAA_22 PF13401.6 EKX42314.1 - 0.052 13.8 0.0 3.7 7.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain Peptidase_C48 PF02902.19 EKX42315.1 - 2.1e-33 116.0 0.0 2.5e-33 115.8 0.0 1.0 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain LupA PF18242.1 EKX42315.1 - 0.027 14.1 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Legionella ubiquitin-specific protease A domain TNFR_c6 PF00020.18 EKX42316.1 - 1.3e-07 31.9 31.7 2.9e-06 27.6 11.0 3.9 2 1 1 3 3 3 3 TNFR/NGFR cysteine-rich region Bac_rhodopsin PF01036.18 EKX42317.1 - 4.8e-10 39.4 17.3 7.1e-10 38.8 17.3 1.2 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein NPR3 PF03666.13 EKX42317.1 - 6.5 5.4 8.9 8.7 5.0 8.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 YceD PF02620.17 EKX42318.1 - 1.3e-16 60.8 0.5 2.4e-16 59.9 0.5 1.5 1 0 0 1 1 1 1 Large ribosomal RNA subunit accumulation protein YceD Ank_2 PF12796.7 EKX42324.1 - 5.7e-43 145.4 2.5 3.6e-13 49.9 0.2 3.9 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX42324.1 - 1.2e-34 118.3 0.7 1.7e-07 31.7 0.0 5.1 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EKX42324.1 - 7.9e-26 89.3 1.6 1.1e-05 25.7 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 EKX42324.1 - 1.6e-25 88.8 1.8 6.7e-08 32.6 0.0 5.7 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX42324.1 - 1.8e-21 73.9 0.2 0.0017 18.7 0.0 7.2 8 0 0 8 8 8 4 Ankyrin repeat DUF3718 PF12514.8 EKX42324.1 - 0.05 13.8 0.3 4.1 7.6 0.0 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3718) APH PF01636.23 EKX42325.1 - 1.4e-16 61.2 0.0 2.5e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EKX42325.1 - 0.007 16.0 0.1 0.031 13.8 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase NS3_envE PF02723.14 EKX42325.1 - 0.1 12.7 0.6 0.24 11.5 0.2 1.9 1 1 1 2 2 2 0 Non-structural protein NS3/Small envelope protein E Bac_rhodopsin PF01036.18 EKX42326.1 - 5.1e-22 78.6 11.2 8.6e-22 77.8 11.2 1.3 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Adeno_E3B PF03376.14 EKX42326.1 - 0.69 10.2 3.5 0.51 10.6 1.2 2.0 2 0 0 2 2 2 0 Adenovirus E3B protein Zip PF02535.22 EKX42327.1 - 1e-11 44.7 11.5 1e-09 38.1 5.0 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter PSI PF01437.25 EKX42328.1 - 0.0067 16.9 26.4 0.075 13.6 26.4 2.6 1 1 0 1 1 1 1 Plexin repeat Glutaredoxin2_C PF04399.13 EKX42328.1 - 0.24 11.3 0.0 0.41 10.5 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain PDZ_2 PF13180.6 EKX42329.1 - 6.5e-05 23.2 0.0 9.9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX42329.1 - 0.00076 19.3 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Ribosomal_L34e PF01199.18 EKX42332.1 - 1.3e-39 134.3 6.4 1.9e-39 133.9 6.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Rdx PF10262.9 EKX42333.1 - 9.7e-19 67.4 0.0 1.4e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Rdx family COMM_domain PF07258.14 EKX42335.1 - 6.3e-14 51.9 0.9 8.6e-14 51.4 0.9 1.2 1 0 0 1 1 1 1 COMM domain RNA_binding PF01877.17 EKX42335.1 - 0.039 14.2 0.4 0.071 13.4 0.4 1.5 1 0 0 1 1 1 0 RNA binding DUF4407 PF14362.6 EKX42336.1 - 1.2 8.4 5.8 3.5 6.9 2.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) MIB_HERC2 PF06701.13 EKX42337.1 - 4e-07 30.2 8.0 4.3e-05 23.7 8.0 2.8 1 1 0 1 1 1 1 Mib_herc2 zf-rbx1 PF12678.7 EKX42337.1 - 3.5e-05 24.0 3.1 7.6e-05 22.9 3.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EKX42337.1 - 9.6e-05 22.1 0.2 0.00027 20.7 0.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX42337.1 - 0.00012 22.4 4.8 0.00047 20.4 4.8 2.1 1 1 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EKX42337.1 - 0.00026 20.6 0.1 0.00083 19.1 0.1 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EKX42337.1 - 0.00034 20.6 1.2 0.00088 19.2 1.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EKX42337.1 - 0.00044 20.1 1.0 0.0012 18.7 1.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EKX42337.1 - 0.014 15.0 0.4 0.014 15.0 0.4 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EKX42337.1 - 0.069 13.0 1.6 0.18 11.7 0.2 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EKX42337.1 - 0.1 12.7 1.0 0.23 11.6 1.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EKX42337.1 - 0.6 10.1 2.1 1.5 8.9 2.2 1.8 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EKX42337.1 - 0.67 9.9 2.8 0.39 10.6 0.3 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MFS_1 PF07690.16 EKX42338.1 - 0.0078 15.2 0.0 0.0085 15.1 0.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Csm1_N PF18504.1 EKX42338.1 - 0.011 16.0 2.1 0.017 15.4 2.1 1.3 1 0 0 1 1 1 0 Csm1 N-terminal domain YscO PF07321.12 EKX42338.1 - 0.011 15.7 1.0 0.016 15.2 1.0 1.1 1 0 0 1 1 1 0 Type III secretion protein YscO End3 PF12761.7 EKX42338.1 - 0.014 15.6 1.0 0.019 15.2 1.0 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Dynamitin PF04912.14 EKX42338.1 - 0.016 14.6 2.6 0.02 14.2 2.6 1.1 1 0 0 1 1 1 0 Dynamitin TMF_DNA_bd PF12329.8 EKX42338.1 - 0.023 14.7 4.8 0.032 14.2 4.8 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF812 PF05667.11 EKX42338.1 - 0.024 13.5 1.1 0.029 13.3 1.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) PEARLI-4 PF05278.12 EKX42338.1 - 0.025 14.2 1.5 0.034 13.8 1.5 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Lebercilin PF15619.6 EKX42338.1 - 0.049 13.3 3.5 0.066 12.9 3.5 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Ax_dynein_light PF10211.9 EKX42338.1 - 0.067 13.1 2.9 0.091 12.7 2.9 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain SlyX PF04102.12 EKX42338.1 - 0.08 13.6 0.5 0.13 12.9 0.5 1.3 1 0 0 1 1 1 0 SlyX TSC22 PF01166.18 EKX42338.1 - 0.17 12.2 2.0 0.27 11.6 2.0 1.3 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF5320 PF17253.2 EKX42338.1 - 0.18 12.9 0.1 0.56 11.3 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Trimer_CC PF08954.11 EKX42338.1 - 0.44 10.1 6.9 0.9 9.2 6.5 1.7 1 1 1 2 2 2 0 Trimerisation motif BRI3BP PF14965.6 EKX42338.1 - 1.1 8.7 4.0 2.2 7.7 4.0 1.6 1 1 0 1 1 1 0 Negative regulator of p53/TP53 TRM13 PF05206.14 EKX42339.1 - 0.039 13.5 0.7 0.039 13.5 0.7 3.6 3 1 0 3 3 3 0 Methyltransferase TRM13 DUF4611 PF15387.6 EKX42340.1 - 0.042 14.1 3.4 0.42 10.9 2.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Myc_N PF01056.18 EKX42340.1 - 0.054 13.4 1.8 0.083 12.8 1.8 1.2 1 0 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.10 EKX42340.1 - 0.062 13.7 5.4 0.12 12.8 5.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain MCRA PF06100.11 EKX42340.1 - 0.16 10.7 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 MCRA family DUF2457 PF10446.9 EKX42340.1 - 0.21 10.7 3.0 0.29 10.2 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Dicty_REP PF05086.12 EKX42340.1 - 0.85 7.5 5.1 1.1 7.1 5.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Cwf_Cwc_15 PF04889.12 EKX42340.1 - 1.1 9.0 5.9 1.6 8.4 5.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 EKX42340.1 - 3.1 7.0 5.4 5 6.4 5.4 1.3 1 0 0 1 1 1 0 NOA36 protein PDZ_6 PF17820.1 EKX42341.1 - 0.0099 15.7 0.3 0.023 14.5 0.3 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX42341.1 - 0.12 12.7 0.0 0.44 10.9 0.0 2.0 2 0 0 2 2 2 0 PDZ domain PDZ PF00595.24 EKX42341.1 - 0.13 12.6 0.1 0.28 11.6 0.1 1.4 1 0 0 1 1 1 0 PDZ domain Ion_trans PF00520.31 EKX42342.1 - 8.2e-25 87.4 19.6 1.3e-24 86.8 19.6 1.3 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EKX42342.1 - 4.7e-07 28.8 12.9 6.8e-07 28.3 12.9 1.2 1 0 0 1 1 1 1 Polycystin cation channel PH PF00169.29 EKX42342.1 - 6.3e-06 26.7 0.0 1.6e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_4 PF15404.6 EKX42342.1 - 9.9e-05 22.2 0.1 0.00019 21.3 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 EKX42342.1 - 0.024 14.5 0.2 0.059 13.2 0.2 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain EF-hand_1 PF00036.32 EKX42342.1 - 0.067 12.8 0.1 0.22 11.1 0.1 2.0 1 0 0 1 1 1 0 EF hand Vac_Fusion PF02346.16 EKX42342.1 - 0.13 11.9 1.0 0.87 9.3 1.0 2.4 1 1 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 Ion_trans PF00520.31 EKX42343.1 - 4.3e-28 98.2 20.1 6.1e-28 97.7 20.1 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EKX42343.1 - 2.6e-07 29.7 12.4 3.7e-07 29.2 12.4 1.2 1 0 0 1 1 1 1 Polycystin cation channel PH PF00169.29 EKX42343.1 - 1.1e-05 25.8 0.0 3.1e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_4 PF15404.6 EKX42343.1 - 0.00024 21.0 0.3 0.00042 20.2 0.3 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3112 PF11309.8 EKX42343.1 - 0.0021 17.6 0.6 0.072 12.5 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3112) PH_13 PF16652.5 EKX42343.1 - 0.028 14.2 0.2 0.068 13.0 0.2 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain EF-hand_1 PF00036.32 EKX42343.1 - 0.079 12.5 0.1 0.26 11.0 0.1 2.0 1 0 0 1 1 1 0 EF hand Vac_Fusion PF02346.16 EKX42343.1 - 0.16 11.6 1.0 1 9.1 1.0 2.4 1 1 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 Glyco_transf_15 PF01793.16 EKX42343.1 - 0.64 9.2 2.7 1.3 8.2 2.7 1.4 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF2046 PF09755.9 EKX42344.1 - 0.0032 16.8 1.7 0.0059 15.9 1.7 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) Phage_lysozyme PF00959.19 EKX42344.1 - 0.044 14.2 1.1 0.079 13.4 1.1 1.4 1 0 0 1 1 1 0 Phage lysozyme Casc1 PF12366.8 EKX42344.1 - 0.047 13.2 3.2 0.078 12.5 3.2 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 TPR_MLP1_2 PF07926.12 EKX42344.1 - 0.063 13.3 9.3 0.1 12.6 9.3 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3464 PF11947.8 EKX42344.1 - 0.1 12.4 1.0 0.17 11.6 1.0 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Laminin_II PF06009.12 EKX42344.1 - 0.12 12.4 3.3 0.2 11.7 3.3 1.3 1 0 0 1 1 1 0 Laminin Domain II Vps5 PF09325.10 EKX42344.1 - 0.66 9.5 6.9 1 8.8 6.9 1.2 1 0 0 1 1 1 0 Vps5 C terminal like EMC3_TMCO1 PF01956.16 EKX42344.1 - 1.1 9.0 11.5 2 8.1 11.5 1.5 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Gln-synt_C PF00120.24 EKX42345.1 - 7.7e-11 41.6 0.0 1.5e-07 30.7 0.0 2.0 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EKX42345.1 - 0.00028 20.6 0.0 0.00045 19.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain ArfGap PF01412.18 EKX42346.1 - 7.3e-26 90.5 1.3 8.4e-26 90.3 1.3 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DHC_N1 PF08385.12 EKX42347.1 - 1.4e-185 618.2 15.5 1.4e-185 618.2 15.5 3.3 4 0 0 4 4 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 EKX42347.1 - 1.6e-138 461.2 4.6 1.6e-137 457.9 0.0 4.0 5 0 0 5 5 5 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EKX42347.1 - 1.8e-123 412.6 0.6 1.8e-123 412.6 0.6 5.2 6 2 0 6 6 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EKX42347.1 - 5.4e-93 311.1 0.0 1.5e-92 309.6 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EKX42347.1 - 1.3e-89 300.4 0.0 9.9e-89 297.6 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EKX42347.1 - 6.1e-80 267.5 0.2 6.1e-80 267.5 0.2 3.5 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 EKX42347.1 - 4e-62 208.9 0.5 8.6e-57 191.6 0.0 4.0 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EKX42347.1 - 1.9e-53 180.7 0.1 6.3e-53 178.9 0.1 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 EKX42347.1 - 6.8e-44 150.3 13.6 6.8e-44 150.3 13.6 2.3 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EKX42347.1 - 2.2e-40 137.4 0.0 7.7e-39 132.5 0.0 3.6 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EKX42347.1 - 5.5e-22 78.2 2.8 2.3e-21 76.2 0.2 3.5 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EKX42347.1 - 4.3e-19 68.6 0.4 3.3e-18 65.7 0.0 2.9 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 EKX42347.1 - 2.3e-17 63.3 0.0 2.3e-08 34.2 0.0 5.1 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA PF00004.29 EKX42347.1 - 4.1e-08 33.7 1.3 0.18 12.2 0.0 5.5 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EKX42347.1 - 0.00012 22.3 2.5 0.96 9.7 0.0 5.3 5 0 0 5 5 5 1 AAA domain AAA_18 PF13238.6 EKX42347.1 - 0.0024 18.4 0.2 2.6 8.6 0.0 4.4 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 EKX42347.1 - 0.018 14.1 0.0 0.94 8.5 0.0 3.0 3 0 0 3 3 3 0 Type II/IV secretion system protein Ribosomal_L18_c PF14204.6 EKX42347.1 - 0.028 15.4 4.9 0.066 14.1 1.2 3.5 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region DUF5040 PF16443.5 EKX42347.1 - 0.033 13.6 0.1 0.11 11.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5040) AAA_30 PF13604.6 EKX42347.1 - 0.19 11.4 6.0 0.21 11.3 0.2 2.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EKX42347.1 - 0.44 11.1 5.9 0.14 12.6 0.1 3.3 3 0 0 3 3 2 0 ABC transporter Cep57_CLD_2 PF14197.6 EKX42347.1 - 1.9 8.6 6.7 0.88 9.7 0.7 3.4 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 AAA_33 PF13671.6 EKX42347.1 - 4.2 7.5 4.7 19 5.4 0.1 4.1 4 0 0 4 4 4 0 AAA domain AAA_19 PF13245.6 EKX42347.1 - 9.7 6.5 9.5 24 5.2 0.0 4.8 4 0 0 4 4 4 0 AAA domain Pkinase PF00069.25 EKX42348.1 - 4.2e-58 196.8 0.0 5.3e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX42348.1 - 2e-36 125.6 0.0 2.8e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EKX42348.1 - 7.1e-14 51.9 0.0 1.6e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 EKX42348.1 - 0.00058 18.8 0.0 0.00086 18.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase LUC7 PF03194.15 EKX42349.1 - 1.1e-40 139.9 3.1 1.1e-40 139.9 3.1 2.6 2 1 1 3 3 3 1 LUC7 N_terminus FlxA PF14282.6 EKX42349.1 - 0.4 10.7 10.0 1.9 8.5 1.1 2.9 2 0 0 2 2 2 0 FlxA-like protein SlyX PF04102.12 EKX42349.1 - 0.5 11.0 14.1 0.93 10.2 1.7 4.2 4 0 0 4 4 4 0 SlyX DUF16 PF01519.16 EKX42349.1 - 4.4 7.9 10.0 2.9 8.4 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 Ferritin PF00210.24 EKX42350.1 - 1.6e-29 102.7 0.4 2.2e-29 102.2 0.4 1.2 1 0 0 1 1 1 1 Ferritin-like domain Pro_isomerase PF00160.21 EKX42351.1 - 1.1e-51 175.3 0.1 1.2e-51 175.1 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TIG PF01833.24 EKX42352.1 - 4.6e-09 36.2 10.3 0.0015 18.6 0.1 7.5 8 0 0 8 8 8 3 IPT/TIG domain DUF1069 PF06370.11 EKX42352.1 - 0.032 13.8 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1069) LRR_6 PF13516.6 EKX42353.1 - 1.3e-24 84.0 36.4 4.9e-06 26.2 0.1 11.6 12 1 0 12 12 12 6 Leucine Rich repeat LRR_4 PF12799.7 EKX42353.1 - 1.6e-08 34.7 23.1 0.015 15.7 0.4 7.0 3 2 4 8 8 8 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX42353.1 - 0.00031 20.9 11.8 21 6.2 0.7 7.7 7 3 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.6 EKX42353.1 - 0.0024 17.6 26.0 0.067 13.0 0.5 7.5 6 2 1 7 7 7 4 Leucine rich repeat DUF4872 PF16169.5 EKX42353.1 - 0.093 12.5 0.1 6.4 6.5 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4872) IMS PF00817.20 EKX42353.1 - 0.16 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 impB/mucB/samB family Acetyltransf_3 PF13302.7 EKX42355.1 - 1.9e-32 112.8 0.9 2.3e-32 112.5 0.2 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EKX42355.1 - 4.2e-11 43.1 0.2 8.5e-11 42.1 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EKX42355.1 - 4e-09 36.3 0.3 2.4e-08 33.8 0.3 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EKX42355.1 - 1.7e-06 28.3 1.9 3.3e-06 27.3 1.9 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 EKX42355.1 - 6e-05 22.7 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase FR47 PF08445.10 EKX42355.1 - 0.00012 22.0 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EKX42355.1 - 0.00039 20.3 0.7 0.00063 19.7 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EKX42355.1 - 0.0015 18.9 0.1 0.0027 18.1 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GrpE PF01025.19 EKX42356.1 - 4.1e-42 143.7 7.8 4.1e-42 143.7 7.8 2.1 1 1 1 2 2 2 1 GrpE ADIP PF11559.8 EKX42356.1 - 1.3 9.1 15.0 3.6 7.7 7.0 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2203 PF09969.9 EKX42356.1 - 2.9 8.6 7.1 1.2 9.9 3.2 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF5320 PF17253.2 EKX42356.1 - 4.1 8.5 6.1 0.86 10.7 2.3 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Fib_alpha PF08702.10 EKX42356.1 - 7.1 6.8 7.8 3.5 7.8 1.3 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CHDCT2 PF08074.11 EKX42356.1 - 8.7 6.5 7.4 4.7 7.4 2.1 2.2 1 1 2 3 3 3 0 CHDCT2 (NUC038) domain GST_N_3 PF13417.6 EKX42358.1 - 1.9e-05 25.0 0.0 4.9e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 EKX42358.1 - 0.00067 19.8 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.6 EKX42358.1 - 0.0037 17.2 0.0 0.0063 16.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EKX42358.1 - 0.056 14.2 0.0 0.15 12.8 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain GST_N PF02798.20 EKX42358.1 - 0.15 12.4 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain zf-C3HC4_3 PF13920.6 EKX42359.1 - 1.4e-13 50.4 8.4 1.4e-13 50.4 8.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX42359.1 - 1.1e-07 31.6 10.4 1.1e-07 31.6 10.4 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EKX42359.1 - 0.00029 20.7 10.9 0.00029 20.7 10.9 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 EKX42359.1 - 0.00039 20.7 10.9 0.00039 20.7 10.9 1.9 2 0 0 2 2 2 1 Ring finger domain ProRS-C_1 PF09180.11 EKX42359.1 - 0.32 11.2 2.9 2.2 8.6 0.0 2.8 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal MgtE_N PF03448.17 EKX42360.1 - 0.0087 16.6 0.1 0.0087 16.6 0.1 2.7 3 0 0 3 3 3 1 MgtE intracellular N domain TPT PF03151.16 EKX42361.1 - 2.6e-74 250.2 9.1 3.9e-74 249.6 9.1 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EKX42361.1 - 5.1e-07 29.9 24.6 0.0069 16.6 9.1 3.2 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EKX42361.1 - 0.021 14.0 11.8 0.02 14.1 9.5 1.9 1 1 0 1 1 1 0 UAA transporter family Bin3 PF06859.12 EKX42362.1 - 2.6e-29 102.0 0.0 6.6e-29 100.7 0.0 1.7 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.6 EKX42362.1 - 1.3e-11 44.6 0.1 2.1e-11 43.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX42362.1 - 1.9e-11 44.1 0.0 2.9e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX42362.1 - 6.2e-10 39.6 0.0 2.2e-09 37.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX42362.1 - 1.2e-09 38.8 0.0 3.5e-09 37.3 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX42362.1 - 2.6e-08 34.4 0.0 5.1e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 EKX42362.1 - 1.2e-05 25.0 0.1 1.8e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_32 PF13679.6 EKX42362.1 - 2.1e-05 24.6 0.0 3.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EKX42362.1 - 0.0001 21.7 0.0 0.00015 21.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 EKX42362.1 - 0.00014 21.8 0.0 0.00028 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EKX42362.1 - 0.00055 19.7 0.0 0.00091 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.11 EKX42362.1 - 0.0063 16.2 0.1 0.044 13.4 0.1 2.1 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.11 EKX42362.1 - 0.0071 15.3 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.17 EKX42362.1 - 0.01 15.3 0.1 0.07 12.6 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.14 EKX42362.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 EKX42362.1 - 0.012 15.1 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Coprogen_oxidas PF01218.18 EKX42363.1 - 9.5e-128 425.1 0.1 1.3e-127 424.6 0.1 1.2 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Glyoxalase PF00903.25 EKX42364.1 - 4.7e-05 23.6 0.0 5.5e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EKX42364.1 - 5.6e-05 23.9 0.0 6.4e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain TruB_C PF09142.11 EKX42364.1 - 0.01 15.6 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal Glyoxalase_2 PF12681.7 EKX42364.1 - 0.017 15.1 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 Glyoxalase-like domain SnoaL_2 PF12680.7 EKX42365.1 - 0.017 15.7 0.0 0.042 14.5 0.0 1.7 2 0 0 2 2 2 0 SnoaL-like domain E1_dh PF00676.20 EKX42366.1 - 1.3e-56 191.7 0.0 2.1e-56 191.1 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_C PF02780.20 EKX42366.1 - 2.9e-27 95.0 0.1 7.5e-27 93.7 0.1 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 EKX42366.1 - 2.5e-12 46.8 0.0 4.4e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.21 EKX42366.1 - 3.2e-05 23.8 0.2 8.3e-05 22.4 0.2 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 EKX42366.1 - 0.00019 20.7 0.0 0.00036 19.8 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase PFOR_II PF17147.4 EKX42366.1 - 0.029 14.7 0.0 0.14 12.5 0.0 2.1 2 0 0 2 2 2 0 Pyruvate:ferredoxin oxidoreductase core domain II TIG PF01833.24 EKX42367.1 - 3.9e-20 71.7 28.8 0.00076 19.5 0.0 10.4 9 2 0 9 9 9 8 IPT/TIG domain TIG_plexin PF17960.1 EKX42367.1 - 0.00083 19.3 8.8 2.8 8.0 0.0 5.3 5 0 0 5 5 5 2 TIG domain Adeno_PIX PF03955.14 EKX42367.1 - 0.00085 19.5 0.9 0.014 15.6 0.4 2.8 2 0 0 2 2 2 1 Adenovirus hexon-associated protein (IX) DUF948 PF06103.11 EKX42368.1 - 0.01 16.1 0.1 0.05 13.9 0.1 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) COG2 PF06148.11 EKX42368.1 - 0.074 13.1 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 TMEM220 PF15071.6 EKX42368.1 - 0.1 13.3 1.8 0.51 11.1 1.7 2.3 2 0 0 2 2 2 0 Transmembrane family 220, helix PKK PF12474.8 EKX42368.1 - 0.47 10.6 7.7 0.19 11.8 3.0 2.5 2 1 1 3 3 3 0 Polo kinase kinase Phage_holin_3_6 PF07332.11 EKX42368.1 - 1 9.4 9.9 0.18 11.8 3.6 2.9 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Glycos_transf_1 PF00534.20 EKX42369.1 - 2.9e-35 121.4 0.0 3.8e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EKX42369.1 - 3.2e-15 56.7 0.0 5.9e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EKX42369.1 - 3.3e-15 56.5 0.2 4.5e-15 56.1 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 EKX42369.1 - 2.6e-08 34.2 0.0 5.9e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EKX42369.1 - 2.1e-07 31.5 0.0 3.2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_5 PF16994.5 EKX42369.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl-transferase family 4 ALG11_N PF15924.5 EKX42369.1 - 0.25 11.4 4.1 10 6.1 1.4 3.5 2 1 1 3 3 3 0 ALG11 mannosyltransferase N-terminus SSF PF00474.17 EKX42370.1 - 5.2e-56 190.2 12.3 6.8e-56 189.9 12.3 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family SSF PF00474.17 EKX42371.1 - 2.1e-21 76.3 9.6 1.2e-20 73.8 9.6 1.8 1 1 0 1 1 1 1 Sodium:solute symporter family Ferric_reduct PF01794.19 EKX42371.1 - 0.049 13.8 5.3 0.29 11.2 5.5 2.3 1 1 0 1 1 1 0 Ferric reductase like transmembrane component FtsX PF02687.21 EKX42371.1 - 0.11 13.0 6.9 0.65 10.5 0.2 2.3 2 0 0 2 2 2 0 FtsX-like permease family TssN PF17555.2 EKX42371.1 - 0.75 9.1 3.3 0.94 8.8 3.3 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN Pkinase PF00069.25 EKX42372.1 - 1.8e-35 122.6 0.8 1.1e-26 93.7 0.5 3.2 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EKX42372.1 - 9e-21 74.3 1.4 1.1e-16 60.9 0.6 3.0 2 1 1 3 3 3 2 Protein tyrosine kinase PBD PF00786.28 EKX42372.1 - 5.2e-09 36.3 0.3 0.0018 18.6 0.2 2.6 2 0 0 2 2 2 2 P21-Rho-binding domain SUIM_assoc PF16619.5 EKX42372.1 - 0.024 14.7 0.6 0.044 13.8 0.6 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Homeobox_KN PF05920.11 EKX42373.1 - 1.6e-16 59.9 1.0 2e-16 59.6 1.0 1.1 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EKX42373.1 - 5e-08 32.7 0.2 5.3e-08 32.6 0.2 1.2 1 0 0 1 1 1 1 Homeodomain HTH_3 PF01381.22 EKX42373.1 - 0.038 14.0 0.0 0.11 12.6 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix Homez PF11569.8 EKX42373.1 - 0.046 13.2 0.1 0.05 13.1 0.1 1.4 1 1 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez YdaS_antitoxin PF15943.5 EKX42373.1 - 0.058 13.3 0.1 0.099 12.5 0.1 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT SE PF08491.10 EKX42373.1 - 0.063 12.3 0.1 0.068 12.2 0.1 1.0 1 0 0 1 1 1 0 Squalene epoxidase Methyltransf_23 PF13489.6 EKX42374.1 - 4.9e-20 72.0 0.0 6.2e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX42374.1 - 3.5e-14 53.2 0.0 5.2e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX42374.1 - 1.2e-10 42.0 0.0 2.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX42374.1 - 8.3e-10 38.4 0.0 1.5e-09 37.6 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EKX42374.1 - 1.4e-06 28.2 0.0 2.4e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX42374.1 - 0.00017 22.3 0.0 0.00028 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EKX42374.1 - 0.036 13.7 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW ZU5 PF00791.20 EKX42375.1 - 1.9e-05 24.9 0.0 5e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 ZU5 domain TFIIA PF03153.13 EKX42375.1 - 0.00022 21.4 5.4 0.00027 21.1 5.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PRP1_N PF06424.12 EKX42375.1 - 0.0018 18.7 1.1 0.0027 18.1 1.1 1.3 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal SprA-related PF12118.8 EKX42375.1 - 0.002 17.4 2.6 0.002 17.4 2.6 2.1 2 0 0 2 2 2 1 SprA-related family FHIPEP PF00771.20 EKX42375.1 - 0.0025 16.4 0.0 0.0037 15.8 0.0 1.1 1 0 0 1 1 1 1 FHIPEP family V_ATPase_I PF01496.19 EKX42375.1 - 0.11 10.4 3.7 0.15 10.0 3.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 EKX42375.1 - 0.13 11.0 4.7 0.19 10.4 4.7 1.2 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 EKX42375.1 - 0.18 11.0 0.7 0.25 10.5 0.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 EKX42375.1 - 0.24 11.2 10.0 0.36 10.6 10.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 EKX42375.1 - 0.24 11.6 3.2 0.41 10.8 3.2 1.4 1 0 0 1 1 1 0 DDHD domain Spt20 PF12090.8 EKX42375.1 - 0.28 10.8 15.8 0.47 10.0 15.8 1.2 1 0 0 1 1 1 0 Spt20 family CDC45 PF02724.14 EKX42375.1 - 0.74 8.0 5.6 1 7.6 5.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Connexin PF00029.19 EKX42375.1 - 0.91 9.2 3.0 1.6 8.4 3.0 1.3 1 0 0 1 1 1 0 Connexin RPN2_C PF18004.1 EKX42375.1 - 1.1 9.1 8.5 2.4 8.1 8.5 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4770 PF15994.5 EKX42375.1 - 1.2 9.3 5.2 2.2 8.5 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF4175 PF13779.6 EKX42375.1 - 1.4 6.8 15.7 1.9 6.3 15.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4746 PF15928.5 EKX42375.1 - 1.7 8.0 12.6 3.4 7.0 12.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CPSF100_C PF13299.6 EKX42375.1 - 4.1 7.6 8.1 4.1 7.6 5.8 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF1682 PF07946.14 EKX42375.1 - 4.3 6.5 6.6 6.3 5.9 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) FAM176 PF14851.6 EKX42375.1 - 4.7 6.9 9.8 5.1 6.8 8.5 1.7 2 0 0 2 2 2 0 FAM176 family DUF4834 PF16118.5 EKX42375.1 - 4.9 8.2 11.7 11 7.0 11.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) MRNIP PF15749.5 EKX42375.1 - 6 7.6 14.3 11 6.8 14.3 1.3 1 0 0 1 1 1 0 MRN-interacting protein Spt20 PF12090.8 EKX42377.1 - 0.0029 17.3 6.9 0.0064 16.1 6.9 1.6 1 0 0 1 1 1 1 Spt20 family SPRY PF00622.28 EKX42377.1 - 0.0044 17.1 0.3 0.01 16.0 0.3 1.7 1 1 0 1 1 1 1 SPRY domain Med15 PF09606.10 EKX42377.1 - 0.5 9.0 16.5 0.74 8.4 16.5 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pox_F11 PF04943.12 EKX42377.1 - 1.4 7.9 7.8 2.9 6.8 7.8 1.5 1 0 0 1 1 1 0 Poxvirus F11 protein Med3 PF11593.8 EKX42377.1 - 2.5 7.2 10.0 5.7 6.0 10.0 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RIFIN PF02009.16 EKX42378.1 - 0.015 15.2 0.1 0.017 15.0 0.1 1.1 1 0 0 1 1 1 0 Rifin DUF5383 PF17355.2 EKX42378.1 - 0.026 14.9 0.6 0.098 13.0 0.6 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5383) Shisa PF13908.6 EKX42378.1 - 0.1 12.8 0.5 0.13 12.5 0.5 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator NDUFB10 PF10249.9 EKX42379.1 - 0.049 14.1 0.1 0.055 14.0 0.1 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 HIT PF01230.23 EKX42381.1 - 9.7e-23 80.8 0.0 1.4e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EKX42381.1 - 8.9e-05 22.9 0.0 0.00012 22.5 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding TBD PF12845.7 EKX42381.1 - 0.061 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 TBD domain DUF740 PF05340.12 EKX42382.1 - 0.0086 14.9 0.1 0.012 14.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF740) DUF4405 PF14358.6 EKX42382.1 - 0.026 15.1 0.3 6.2 7.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) YiaAB PF05360.14 EKX42382.1 - 0.25 11.6 2.4 13 6.2 0.1 2.4 2 0 0 2 2 2 0 yiaA/B two helix domain PHD PF00628.29 EKX42383.1 - 3.5e-24 84.4 20.4 6.8e-12 45.1 11.5 2.0 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 EKX42383.1 - 0.00014 21.3 21.1 0.00037 20.0 0.8 3.2 3 1 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.6 EKX42383.1 - 0.00063 19.4 4.6 0.091 12.4 1.2 2.4 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain C1_2 PF03107.16 EKX42383.1 - 0.087 13.2 2.9 0.087 13.2 2.9 3.9 2 1 1 3 3 3 0 C1 domain Prok-RING_1 PF14446.6 EKX42383.1 - 0.75 9.8 17.4 0.26 11.2 8.1 2.6 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RRPl_C4 PF17026.5 EKX42383.1 - 0.91 9.7 9.4 4.1 7.5 9.4 2.0 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-HC5HC2H PF13771.6 EKX42383.1 - 2.8 8.3 14.5 3.5 7.9 6.7 2.3 1 1 1 2 2 2 0 PHD-like zinc-binding domain ADK_lid PF05191.14 EKX42383.1 - 3 7.9 14.8 6.5 6.8 2.6 3.0 2 2 0 2 2 2 0 Adenylate kinase, active site lid zf-RING_2 PF13639.6 EKX42383.1 - 4.7 7.6 19.0 6.6 7.2 1.3 2.4 2 0 0 2 2 2 0 Ring finger domain FYVE_2 PF02318.16 EKX42383.1 - 7.2 6.9 14.1 2 8.7 1.0 2.9 1 1 2 3 3 3 0 FYVE-type zinc finger FKBP_C PF00254.28 EKX42384.1 - 2.3e-16 59.9 0.0 3.3e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pro_isomerase PF00160.21 EKX42386.1 - 4.8e-33 114.7 0.0 8.7e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD IQ PF00612.27 EKX42386.1 - 0.031 14.0 0.1 0.07 12.9 0.1 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif Polyketide_cyc2 PF10604.9 EKX42386.1 - 0.059 13.6 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport RGI1 PF10843.8 EKX42388.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Respiratory growth induced protein 1 EspF PF04806.12 EKX42389.1 - 0.032 14.6 0.0 7.7 7.0 0.0 3.2 3 0 0 3 3 3 0 EspF protein repeat Ribonuclease_3 PF00636.26 EKX42389.1 - 2.4 8.8 11.4 4 8.1 8.2 2.8 1 1 1 2 2 2 0 Ribonuclease III domain LRR_6 PF13516.6 EKX42391.1 - 1.3e-13 49.8 21.1 0.02 14.9 0.1 9.1 9 0 0 9 9 9 5 Leucine Rich repeat LRR_4 PF12799.7 EKX42391.1 - 1.2e-07 31.9 10.2 0.04 14.3 0.1 6.2 5 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX42391.1 - 0.017 15.6 3.1 2e+02 3.2 0.0 6.3 7 1 0 7 7 7 0 Leucine Rich Repeat D5_N PF08706.11 EKX42391.1 - 0.11 12.7 5.2 0.069 13.4 2.7 1.8 2 0 0 2 2 2 0 D5 N terminal like LRR_8 PF13855.6 EKX42391.1 - 0.15 11.8 20.0 9.7 6.0 0.2 6.9 5 1 1 6 6 6 0 Leucine rich repeat nsp8 PF08717.10 EKX42391.1 - 0.25 11.2 1.0 14 5.5 0.0 2.6 3 0 0 3 3 3 0 nsp8 replicase Ank_2 PF12796.7 EKX42392.1 - 7.6e-18 64.9 0.1 1.4e-08 35.2 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EKX42392.1 - 6.6e-16 58.0 0.1 8.4e-06 26.0 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EKX42392.1 - 1.6e-15 57.0 0.9 1.9e-05 24.8 0.0 2.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX42392.1 - 5.3e-15 55.6 0.2 3.4e-05 24.3 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX42392.1 - 4.9e-14 51.1 0.0 8.2e-05 22.7 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 EKX42393.1 - 2.6e-26 92.0 2.9 4.3e-16 59.3 0.3 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX42393.1 - 5.5e-23 81.0 0.5 6.4e-11 42.6 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX42393.1 - 1.4e-13 50.7 0.2 7.6e-11 42.0 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX42393.1 - 1.5e-13 49.6 0.1 3.9e-06 26.8 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EKX42393.1 - 1.4e-11 44.2 2.9 1.4e-05 25.3 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat SF3A2 PF16835.5 EKX42394.1 - 1.1e-36 125.1 0.1 1.8e-36 124.4 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 EKX42394.1 - 1.9e-07 31.3 0.9 4e-07 30.2 0.9 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 EKX42394.1 - 0.00026 20.9 0.1 0.00046 20.1 0.1 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Utp21 PF04192.12 EKX42395.1 - 3.2e-29 102.1 1.8 5.5e-29 101.3 0.8 1.8 2 0 0 2 2 2 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 EKX42395.1 - 2.2e-13 50.3 0.0 0.021 15.1 0.0 5.4 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EKX42395.1 - 5.1e-12 46.1 4.4 0.00017 22.3 0.2 7.4 8 0 0 8 8 8 2 WD domain, G-beta repeat Surp PF01805.20 EKX42396.1 - 7.2e-18 64.3 0.3 1.4e-17 63.4 0.3 1.5 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 EKX42396.1 - 6.6e-17 61.1 0.0 4.8e-16 58.3 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 EKX42396.1 - 1.5e-07 32.2 0.0 4.5e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_5 PF13893.6 EKX42396.1 - 3.7e-05 23.3 0.0 9.1e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EKX42396.1 - 0.00035 20.6 0.0 0.018 15.2 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif BHD_2 PF10404.9 EKX42396.1 - 0.052 14.5 0.5 0.052 14.5 0.5 2.8 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 2 CTK3 PF12243.8 EKX42396.1 - 0.066 13.2 0.0 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 AP3D1 PF06375.11 EKX42396.1 - 3.1 8.0 7.8 0.51 10.6 0.2 2.3 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 B9-C2 PF07162.11 EKX42397.1 - 1.7e-46 158.5 0.0 2e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein AAA_11 PF13086.6 EKX42398.1 - 5.5e-23 82.1 13.5 5.2e-18 65.8 0.2 3.8 2 2 1 3 3 2 2 AAA domain AAA_12 PF13087.6 EKX42398.1 - 1.5e-16 60.7 0.0 3.1e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EKX42398.1 - 6.5e-07 29.3 0.0 6.6e-05 22.8 0.0 2.4 1 1 1 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 EKX42398.1 - 1.5e-06 28.6 0.0 4e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EKX42398.1 - 6.8e-06 25.9 0.0 1.8e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EKX42398.1 - 0.0015 18.5 0.0 0.0089 16.0 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Bac_DnaA PF00308.18 EKX42398.1 - 0.0017 18.3 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial dnaA protein MRNIP PF15749.5 EKX42398.1 - 0.0099 16.6 0.1 0.0099 16.6 0.1 2.9 3 0 0 3 3 3 1 MRN-interacting protein DUF2439 PF10382.9 EKX42398.1 - 0.011 16.1 0.0 0.025 14.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2439) AAA_22 PF13401.6 EKX42398.1 - 0.024 14.9 0.0 0.13 12.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 EKX42398.1 - 0.062 12.8 0.0 3.7 7.0 0.0 2.5 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain PIF1 PF05970.14 EKX42398.1 - 0.075 12.2 0.0 10 5.2 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_29 PF13555.6 EKX42398.1 - 0.15 11.9 0.0 0.42 10.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EKX42398.1 - 0.44 11.0 0.0 0.44 11.0 0.0 2.5 2 1 1 3 3 3 0 AAA domain DUF1860 PF08949.10 EKX42398.1 - 3.8 7.2 5.2 6.2 6.5 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1860) Sec7 PF01369.20 EKX42399.1 - 1.1e-71 240.3 0.0 3.2e-71 238.8 0.0 1.8 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EKX42399.1 - 5.1e-43 146.7 7.5 9.6e-43 145.8 3.1 2.5 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EKX42399.1 - 1.9e-29 101.3 6.4 1.2e-28 98.8 0.1 4.8 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) DCB PF16213.5 EKX42399.1 - 2.7e-24 85.8 0.2 2.7e-24 85.8 0.2 2.9 3 1 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 EKX42399.1 - 8.2e-09 34.2 0.1 3.9e-05 22.0 0.0 2.5 2 0 0 2 2 2 2 C-terminal region of Mon2 protein DUF4255 PF14065.6 EKX42400.1 - 0.014 15.1 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4255) SNF2_N PF00176.23 EKX42401.1 - 8.3e-31 107.0 0.0 1.3e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HARP PF07443.13 EKX42401.1 - 3.1e-15 55.6 0.0 1.2e-14 53.7 0.0 2.1 1 0 0 1 1 1 1 HepA-related protein (HARP) Helicase_C PF00271.31 EKX42401.1 - 1.6e-07 31.6 0.1 3.7e-06 27.2 0.0 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX42401.1 - 4.4e-07 30.1 0.8 5.5e-06 26.5 0.0 2.8 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 EKX42401.1 - 0.0085 16.1 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain TniB PF05621.11 EKX42401.1 - 0.063 12.7 0.2 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein Caldesmon PF02029.15 EKX42402.1 - 0.00053 18.9 31.3 0.00081 18.3 31.3 1.3 1 0 0 1 1 1 1 Caldesmon Plasmodium_Vir PF05795.11 EKX42402.1 - 0.0011 18.4 11.7 0.0017 17.9 11.7 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Presenilin PF01080.17 EKX42402.1 - 0.0048 15.7 25.1 0.0068 15.2 25.1 1.1 1 0 0 1 1 1 1 Presenilin Spore_coat_CotO PF14153.6 EKX42402.1 - 0.0052 16.7 27.4 0.0094 15.9 27.4 1.4 1 0 0 1 1 1 1 Spore coat protein CotO DUF4045 PF13254.6 EKX42402.1 - 0.0069 16.1 16.2 0.0085 15.8 16.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4045) CCSAP PF15748.5 EKX42402.1 - 0.036 14.2 23.3 0.065 13.4 23.3 1.4 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated BUD22 PF09073.10 EKX42402.1 - 0.037 13.4 42.1 0.055 12.8 42.1 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 EKX42402.1 - 0.17 10.1 46.3 0.25 9.5 46.3 1.2 1 0 0 1 1 1 0 Nop14-like family NPR3 PF03666.13 EKX42402.1 - 0.17 10.6 23.8 0.25 10.1 23.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SDA1 PF05285.12 EKX42402.1 - 0.22 10.9 47.8 0.39 10.1 47.8 1.3 1 0 0 1 1 1 0 SDA1 MDM1 PF15501.6 EKX42402.1 - 0.42 9.7 29.1 0.62 9.1 29.1 1.2 1 0 0 1 1 1 0 Nuclear protein MDM1 SAPS PF04499.15 EKX42402.1 - 0.44 9.3 22.2 0.56 8.9 22.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.16 EKX42402.1 - 0.47 10.5 7.7 0.8 9.7 7.7 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region XRN_M PF17846.1 EKX42402.1 - 0.78 8.6 16.2 1.1 8.2 16.2 1.2 1 0 0 1 1 1 0 Xrn1 helical domain Endostatin PF06482.11 EKX42402.1 - 1.1 8.7 8.0 1.6 8.1 8.0 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Peptidase_S64 PF08192.11 EKX42402.1 - 1.7 7.0 15.3 2.3 6.6 15.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 Lin-8 PF03353.15 EKX42402.1 - 1.9 8.0 26.2 3.2 7.3 26.2 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Vfa1 PF08432.10 EKX42402.1 - 3.3 8.0 31.3 8.4 6.7 31.3 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SID-1_RNA_chan PF13965.6 EKX42402.1 - 5.8 5.2 8.1 9 4.6 8.1 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TFIIF_alpha PF05793.12 EKX42402.1 - 7 5.1 47.6 9.9 4.6 47.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cwf_Cwc_15 PF04889.12 EKX42402.1 - 8.5 6.0 43.5 15 5.2 43.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF563 PF04577.14 EKX42404.1 - 0.00025 21.3 0.3 0.021 15.0 0.1 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF563) Tantalus PF15386.6 EKX42404.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Drosophila Tantalus-like Glyco_tranf_2_3 PF13641.6 EKX42404.1 - 0.14 12.0 0.3 2.1 8.2 0.0 2.1 1 1 1 2 2 2 0 Glycosyltransferase like family 2 Peptidase_C97 PF05903.14 EKX42405.1 - 4.4e-21 75.3 0.1 6.5e-10 39.0 0.0 2.1 1 1 1 2 2 2 2 PPPDE putative peptidase domain U-box PF04564.15 EKX42406.1 - 1.2e-19 70.3 0.0 1.3e-19 70.2 0.0 1.0 1 0 0 1 1 1 1 U-box domain GST_N_4 PF17172.4 EKX42406.1 - 0.0025 18.5 0.0 0.0032 18.2 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain DUF2358 PF10184.9 EKX42407.1 - 0.00015 22.0 0.0 0.00016 21.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 EKX42407.1 - 0.0015 19.2 0.0 0.0017 18.9 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain bZIP_1 PF00170.21 EKX42408.1 - 7.3e-09 35.6 7.7 1.4e-08 34.7 7.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EKX42408.1 - 4.9e-05 23.3 7.4 4.9e-05 23.3 7.4 2.9 2 1 1 3 3 3 2 Basic region leucine zipper bZIP_Maf PF03131.17 EKX42408.1 - 0.0011 19.4 8.7 0.0025 18.3 8.7 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor ATG16 PF08614.11 EKX42408.1 - 0.027 14.7 8.0 0.047 13.9 8.0 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4449 PF14613.6 EKX42408.1 - 0.038 14.1 2.2 0.058 13.5 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) GAS PF13851.6 EKX42408.1 - 0.19 11.0 8.5 0.37 10.1 8.5 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding FapA PF03961.13 EKX42408.1 - 0.4 9.2 1.7 0.51 8.9 1.7 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A RRP36 PF06102.12 EKX42408.1 - 1.8 8.5 7.3 2.9 7.8 7.3 1.2 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 DivIC PF04977.15 EKX42408.1 - 2.1 8.2 10.9 3.7 7.4 5.3 2.6 1 1 0 2 2 2 0 Septum formation initiator DUF3847 PF12958.7 EKX42408.1 - 4.6 7.4 9.4 4.5 7.5 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) M PF02370.16 EKX42408.1 - 5.1 8.0 8.9 13 6.8 0.2 3.6 3 0 0 3 3 3 0 M protein repeat YabA PF06156.13 EKX42408.1 - 7.4 7.3 8.5 15 6.3 0.5 2.2 1 1 1 2 2 2 0 Initiation control protein YabA DUF812 PF05667.11 EKX42409.1 - 0.00027 20.0 4.8 0.00033 19.7 4.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) ADIP PF11559.8 EKX42409.1 - 0.00066 19.8 2.1 0.00089 19.4 2.1 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding MAD PF05557.13 EKX42409.1 - 0.0011 17.5 8.8 0.0014 17.1 8.8 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein EzrA PF06160.12 EKX42409.1 - 0.0052 15.0 2.3 0.007 14.6 2.3 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA AAA_11 PF13086.6 EKX42409.1 - 0.0077 16.0 1.7 0.012 15.4 1.7 1.3 1 0 0 1 1 1 1 AAA domain CCDC-167 PF15188.6 EKX42409.1 - 0.012 15.9 4.9 0.025 14.9 4.9 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Golgin_A5 PF09787.9 EKX42409.1 - 0.025 14.1 6.8 0.035 13.6 6.8 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Tektin PF03148.14 EKX42409.1 - 0.051 12.3 6.2 0.072 11.8 6.2 1.1 1 0 0 1 1 1 0 Tektin family MMR1 PF08505.10 EKX42409.1 - 0.066 13.5 0.7 0.086 13.1 0.7 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF724 PF05266.14 EKX42409.1 - 0.17 11.7 6.5 0.24 11.2 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TMPIT PF07851.13 EKX42409.1 - 0.29 10.4 3.0 0.39 9.9 3.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein Nup88 PF10168.9 EKX42409.1 - 0.32 8.7 4.6 0.42 8.4 4.6 1.1 1 0 0 1 1 1 0 Nuclear pore component OmpH PF03938.14 EKX42409.1 - 0.42 11.0 8.6 0.65 10.3 8.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) APG6_N PF17675.1 EKX42409.1 - 0.49 10.9 10.8 0.83 10.2 10.8 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region Atg14 PF10186.9 EKX42409.1 - 0.63 9.1 5.5 0.81 8.7 5.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Seryl_tRNA_N PF02403.22 EKX42409.1 - 0.83 9.9 7.4 1.3 9.2 7.4 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Prefoldin_2 PF01920.20 EKX42409.1 - 1.1 9.3 16.9 0.076 13.0 2.5 2.2 1 1 1 2 2 2 0 Prefoldin subunit DUF4200 PF13863.6 EKX42409.1 - 1.3 9.5 16.9 2.4 8.6 1.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) AAA_13 PF13166.6 EKX42409.1 - 1.4 7.5 8.5 2.7 6.5 7.3 1.4 1 1 0 1 1 1 0 AAA domain YabA PF06156.13 EKX42409.1 - 1.4 9.6 8.0 20 5.9 4.3 2.1 1 1 1 2 2 2 0 Initiation control protein YabA FlaC_arch PF05377.11 EKX42409.1 - 1.7 9.1 9.4 0.095 13.1 3.7 1.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 EKX42409.1 - 5.7 7.0 6.6 1.2 9.1 1.7 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4140 PF13600.6 EKX42409.1 - 7.2 7.1 7.3 2.3 8.7 0.1 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) zf-LITAF-like PF10601.9 EKX42410.1 - 5.4 7.4 8.0 1.3 9.3 3.4 2.4 2 1 1 3 3 3 0 LITAF-like zinc ribbon domain RVT_1 PF00078.27 EKX42411.1 - 5.9e-08 32.5 0.0 0.00012 21.6 0.0 2.8 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) ORC5_C PF14630.6 EKX42411.1 - 0.046 13.2 0.1 0.046 13.2 0.1 4.0 3 1 0 3 3 3 0 Origin recognition complex (ORC) subunit 5 C-terminus GREB1 PF15782.5 EKX42411.1 - 4.1 4.4 36.1 5.6 4.0 36.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ank_2 PF12796.7 EKX42413.1 - 7.5e-25 87.3 0.4 1.1e-13 51.5 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX42413.1 - 2.2e-21 75.9 1.0 6.3e-10 39.4 0.0 3.9 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX42413.1 - 1.7e-17 63.2 1.6 3.1e-09 36.9 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX42413.1 - 6.2e-15 53.8 0.4 2.2e-06 27.6 0.0 4.9 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 EKX42413.1 - 2.5e-12 46.6 4.1 1.4e-05 25.3 0.0 4.9 4 1 0 4 4 4 2 Ankyrin repeat DUF1843 PF08898.10 EKX42413.1 - 0.014 15.9 0.9 0.18 12.4 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) DUF5354 PF17305.2 EKX42413.1 - 0.16 12.2 0.0 9.4 6.5 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5354) DREV PF05219.12 EKX42413.1 - 0.2 10.7 0.1 11 5.0 0.0 2.1 2 0 0 2 2 2 0 DREV methyltransferase Ank_2 PF12796.7 EKX42414.1 - 1.7e-13 50.9 0.2 4.1e-13 49.7 0.2 1.6 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX42414.1 - 2.2e-12 47.3 0.8 4.1e-07 30.4 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX42414.1 - 2.3e-09 37.2 1.0 1e-08 35.2 0.1 2.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EKX42414.1 - 9.4e-07 28.7 0.5 6e-05 23.1 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EKX42414.1 - 4.6e-06 26.8 0.2 1.2e-05 25.5 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) DUF1110 PF06533.12 EKX42414.1 - 0.017 15.1 0.1 0.033 14.2 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1110) DUF3198 PF11433.8 EKX42414.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3198) Ank_4 PF13637.6 EKX42415.1 - 2.7e-17 62.9 0.0 7.1e-09 36.0 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX42415.1 - 4.9e-12 45.8 0.0 1.8e-10 40.8 0.0 1.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX42415.1 - 6e-12 46.0 0.0 1.6e-11 44.6 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX42415.1 - 1.2e-08 35.0 0.0 1.3e-05 25.4 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EKX42415.1 - 1.1e-07 31.5 0.0 0.0002 21.5 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Zn-C2H2_12 PF18112.1 EKX42416.1 - 0.0092 16.4 0.7 0.026 15.0 0.2 2.0 2 0 0 2 2 2 1 Autophagy receptor zinc finger-C2H2 domain FYVE PF01363.21 EKX42416.1 - 0.01 15.9 0.2 0.012 15.8 0.2 1.2 1 0 0 1 1 1 0 FYVE zinc finger zinc-ribbons_6 PF07191.12 EKX42416.1 - 0.015 15.2 2.0 0.022 14.7 2.0 1.2 1 0 0 1 1 1 0 zinc-ribbons DUF2225 PF09986.9 EKX42416.1 - 0.033 13.9 1.1 0.042 13.6 1.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_4 PF13894.6 EKX42416.1 - 0.042 14.7 2.3 3.6 8.7 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger DZR PF12773.7 EKX42416.1 - 0.049 13.7 2.5 0.065 13.3 2.5 1.2 1 0 0 1 1 1 0 Double zinc ribbon CK_II_beta PF01214.18 EKX42416.1 - 0.058 13.2 0.1 0.07 12.9 0.1 1.2 1 0 0 1 1 1 0 Casein kinase II regulatory subunit TRAF6_Z2 PF18048.1 EKX42416.1 - 0.094 12.8 1.6 0.67 10.1 0.1 2.2 1 1 1 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2 PF00096.26 EKX42416.1 - 0.22 12.1 3.0 9.9 6.8 0.5 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-UDP PF14569.6 EKX42416.1 - 0.26 11.4 3.2 0.77 9.9 3.1 1.8 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_5 PF17121.5 EKX42416.1 - 1.1 9.2 6.0 69 3.4 5.9 2.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) LRR_4 PF12799.7 EKX42417.1 - 6e-12 45.6 13.0 1.1e-05 25.6 1.8 4.8 2 2 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX42417.1 - 9e-12 44.8 1.0 1.9e-08 34.0 0.4 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 EKX42417.1 - 4.7e-07 29.5 16.7 0.0028 17.4 5.2 4.3 2 1 3 5 5 5 4 Leucine rich repeat PAS_9 PF13426.7 EKX42418.1 - 6.1e-44 148.5 0.1 1e-12 48.2 0.0 6.0 6 0 0 6 6 6 4 PAS domain PAS PF00989.25 EKX42418.1 - 3e-28 98.1 0.0 1.4e-06 28.3 0.0 5.8 5 0 0 5 5 5 4 PAS fold PAS_4 PF08448.10 EKX42418.1 - 2.7e-19 69.4 0.0 0.00032 20.9 0.0 5.2 4 0 0 4 4 4 3 PAS fold PAS_3 PF08447.12 EKX42418.1 - 1.6e-15 57.1 0.0 0.0015 18.8 0.0 5.1 4 1 0 4 4 4 4 PAS fold PAS_8 PF13188.7 EKX42418.1 - 4.8e-14 52.0 1.1 0.0025 17.8 0.0 5.5 6 0 0 6 6 6 3 PAS domain PAS_7 PF12860.7 EKX42418.1 - 0.00012 22.3 0.0 0.48 10.6 0.0 3.0 2 0 0 2 2 2 2 PAS fold HIP1_clath_bdg PF16515.5 EKX42418.1 - 0.054 14.1 5.4 0.45 11.1 5.4 2.7 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Herpes_UL6 PF01763.16 EKX42418.1 - 0.064 11.8 2.2 0.11 11.0 2.2 1.4 1 0 0 1 1 1 0 Herpesvirus UL6 like PAS_9 PF13426.7 EKX42419.1 - 7.7e-10 39.0 0.0 0.00051 20.3 0.0 2.2 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 EKX42419.1 - 2e-07 31.0 0.0 0.00058 19.9 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 EKX42419.1 - 0.05 13.9 0.0 9.8 6.6 0.0 2.3 2 0 0 2 2 2 0 PAS fold LRR_6 PF13516.6 EKX42420.1 - 2e-24 83.5 22.9 5.3e-06 26.1 0.2 8.3 9 0 0 9 9 9 7 Leucine Rich repeat LRR_8 PF13855.6 EKX42420.1 - 5.5e-12 45.3 8.8 0.00012 21.7 0.2 5.1 3 2 1 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 EKX42420.1 - 3.8e-11 41.9 10.2 0.34 11.6 0.2 7.1 6 1 1 7 7 7 3 Leucine Rich Repeat LRR_4 PF12799.7 EKX42420.1 - 5e-09 36.3 10.0 0.0013 19.1 1.4 4.8 2 1 4 6 6 6 4 Leucine Rich repeats (2 copies) CHD5 PF04420.14 EKX42421.1 - 6.6e-17 61.8 0.2 6.6e-17 61.8 0.2 4.0 2 1 0 2 2 2 1 CHD5-like protein Dapper PF15268.6 EKX42421.1 - 0.063 12.1 30.7 0.08 11.8 30.7 1.0 1 0 0 1 1 1 0 Dapper CAV_VP3 PF04771.12 EKX42421.1 - 0.081 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Chicken anaemia virus VP-3 protein Trypan_PARP PF05887.11 EKX42421.1 - 0.095 12.7 44.7 99 2.9 16.8 3.0 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) RskA PF10099.9 EKX42421.1 - 0.11 12.8 12.5 0.095 13.0 1.5 2.8 1 1 1 2 2 2 0 Anti-sigma-K factor rskA DUF2721 PF11026.8 EKX42421.1 - 0.13 12.1 0.1 0.13 12.1 0.1 4.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2721) YdjM PF04307.14 EKX42421.1 - 0.17 11.1 1.7 0.35 10.1 1.7 1.5 1 1 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase NESP55 PF06390.12 EKX42421.1 - 4.5 6.8 45.6 1.3 8.6 23.2 2.2 1 1 1 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) Baculo_PEP_C PF04513.12 EKX42422.1 - 0.00022 21.3 6.9 1.1 9.3 0.2 3.5 1 1 2 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus Jnk-SapK_ap_N PF09744.9 EKX42422.1 - 0.00057 20.1 4.3 0.00057 20.1 4.3 3.3 1 1 1 3 3 3 1 JNK_SAPK-associated protein-1 DivIC PF04977.15 EKX42422.1 - 0.0029 17.3 1.1 0.0029 17.3 1.1 3.6 4 1 2 6 6 4 1 Septum formation initiator CENP-H PF05837.12 EKX42422.1 - 0.0078 16.6 1.5 0.0078 16.6 1.5 3.3 1 1 1 2 2 1 1 Centromere protein H (CENP-H) Spectrin PF00435.21 EKX42422.1 - 0.0083 16.6 13.1 0.069 13.7 1.2 3.8 1 1 3 4 4 4 1 Spectrin repeat DUF1664 PF07889.12 EKX42422.1 - 0.01 15.9 0.7 0.01 15.9 0.7 3.4 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF2935 PF11155.8 EKX42422.1 - 0.033 14.5 0.6 5.8 7.3 0.3 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) Phage_GPO PF05929.11 EKX42422.1 - 0.035 13.7 16.2 0.14 11.7 4.2 3.2 1 1 2 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase IFT57 PF10498.9 EKX42422.1 - 0.049 12.6 9.8 0.62 9.0 9.7 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF5595 PF18077.1 EKX42422.1 - 0.052 13.6 4.5 1.7 8.7 0.4 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) DUF2746 PF10874.8 EKX42422.1 - 0.084 13.3 0.1 7.4 7.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) TPR_MLP1_2 PF07926.12 EKX42422.1 - 0.091 12.8 18.4 0.11 12.6 3.3 3.8 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein ABC_tran_CTD PF16326.5 EKX42422.1 - 0.099 12.9 18.7 0.38 11.0 2.7 4.0 3 1 2 5 5 5 0 ABC transporter C-terminal domain CAMP_factor PF07373.11 EKX42422.1 - 0.1 12.2 3.5 0.36 10.4 0.1 2.5 1 1 1 2 2 2 0 CAMP factor (Cfa) GAS PF13851.6 EKX42422.1 - 0.11 11.9 17.1 0.016 14.6 4.5 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.7 EKX42422.1 - 0.17 12.1 21.2 10 6.3 9.0 3.2 1 1 2 3 3 3 0 Tropomyosin like DUF4407 PF14362.6 EKX42422.1 - 0.46 9.8 13.5 6.4 6.0 13.5 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 EKX42422.1 - 0.56 10.5 8.4 6.7 7.0 0.1 3.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF883 PF05957.13 EKX42422.1 - 0.74 10.5 12.6 4.1 8.1 0.2 4.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Atg14 PF10186.9 EKX42422.1 - 1.3 8.0 13.4 2.4 7.2 4.0 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 COG5 PF10392.9 EKX42422.1 - 1.5 9.0 8.2 2.7 8.2 0.4 3.1 2 2 0 3 3 3 0 Golgi transport complex subunit 5 zf-C4H2 PF10146.9 EKX42422.1 - 1.5 9.1 5.7 14 5.9 5.7 2.3 1 1 0 1 1 1 0 Zinc finger-containing protein bZIP_1 PF00170.21 EKX42422.1 - 1.6 8.9 8.2 3.1 8.0 1.4 3.7 2 1 3 5 5 4 0 bZIP transcription factor NPV_P10 PF05531.12 EKX42422.1 - 1.7 9.2 11.7 33 5.0 3.1 4.3 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Fungal_TACC PF12709.7 EKX42422.1 - 1.7 9.1 10.5 7.6 7.1 0.5 3.6 2 1 2 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins TMF_TATA_bd PF12325.8 EKX42422.1 - 1.8 8.8 20.5 0.42 10.8 2.1 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF1640 PF07798.11 EKX42422.1 - 2.1 8.4 17.8 0.62 10.1 5.8 3.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) DUF4778 PF16008.5 EKX42422.1 - 2.4 8.1 14.8 0.58 10.2 11.5 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4778) Allexi_40kDa PF05549.11 EKX42422.1 - 2.4 7.6 7.9 1.2 8.6 0.7 2.6 1 1 2 3 3 3 0 Allexivirus 40kDa protein Seryl_tRNA_N PF02403.22 EKX42422.1 - 2.7 8.2 17.6 1.6 9.0 2.8 3.6 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain FlxA PF14282.6 EKX42422.1 - 2.9 8.0 13.0 0.077 13.0 1.7 2.9 1 1 0 2 2 2 0 FlxA-like protein DUF724 PF05266.14 EKX42422.1 - 4.1 7.2 19.7 1.7 8.5 5.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF1003 PF06210.11 EKX42422.1 - 5.1 7.3 6.5 1.6 8.9 0.1 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1003) Bacillus_HBL PF05791.11 EKX42422.1 - 6 6.7 10.0 0.4 10.5 0.3 2.9 1 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF2730 PF10805.8 EKX42422.1 - 6.8 6.9 11.8 4 7.6 0.5 3.7 3 2 0 3 3 3 0 Protein of unknown function (DUF2730) DUF4164 PF13747.6 EKX42422.1 - 7.7 6.9 19.2 0.49 10.7 1.2 4.1 2 2 2 4 4 4 0 Domain of unknown function (DUF4164) DUF1319 PF07028.11 EKX42422.1 - 7.9 6.7 8.1 18 5.6 1.2 3.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) LRR_6 PF13516.6 EKX42423.1 - 2.3e-12 45.9 16.0 0.41 10.8 0.4 7.4 7 0 0 7 7 7 4 Leucine Rich repeat zf-C2H2_jaz PF12171.8 EKX42423.1 - 0.00016 21.8 0.9 0.00034 20.8 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding LRR_1 PF00560.33 EKX42423.1 - 0.00069 19.8 1.3 56 4.9 0.0 6.3 8 0 0 8 8 8 0 Leucine Rich Repeat LRR_4 PF12799.7 EKX42423.1 - 0.0015 18.9 1.5 1.6 9.2 0.1 4.3 5 0 0 5 5 5 1 Leucine Rich repeats (2 copies) zf-met PF12874.7 EKX42423.1 - 0.012 16.0 0.3 0.027 14.9 0.3 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DUF4132 PF13569.6 EKX42423.1 - 0.059 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4132) LRR_8 PF13855.6 EKX42423.1 - 1.9 8.3 9.8 9.1 6.1 1.5 4.9 5 2 1 6 6 6 0 Leucine rich repeat Glutaredoxin PF00462.24 EKX42424.1 - 2.8e-16 59.5 0.0 3.8e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Rhodanese PF00581.20 EKX42425.1 - 6.3e-06 26.7 0.0 7.8e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Abhydrolase_1 PF00561.20 EKX42426.1 - 2.3e-08 34.0 0.0 3.5e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EKX42426.1 - 8.1e-05 23.3 0.0 0.00011 22.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 EKX42426.1 - 0.0018 18.0 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 EKX42426.1 - 0.023 14.5 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Thioesterase PF00975.20 EKX42426.1 - 0.1 12.7 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain FA_desaturase PF00487.24 EKX42427.1 - 1.4e-05 25.1 13.9 0.00032 20.6 13.3 2.4 1 1 0 1 1 1 1 Fatty acid desaturase Keratin_2_head PF16208.5 EKX42427.1 - 0.11 12.7 23.9 0.18 12.0 23.9 1.3 1 0 0 1 1 1 0 Keratin type II head Gln-synt_C PF00120.24 EKX42428.1 - 8.1e-88 294.7 0.0 6.8e-87 291.7 0.0 1.9 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EKX42428.1 - 1.8e-07 30.8 0.2 8.9e-06 25.3 0.0 3.0 3 0 0 3 3 3 1 Glutamine synthetase, beta-Grasp domain Gln-synt_N_2 PF16952.5 EKX42428.1 - 0.00055 19.7 0.1 0.012 15.4 0.0 2.6 2 1 0 2 2 2 1 Glutamine synthetase N-terminal domain Zip PF02535.22 EKX42429.1 - 1.2e-07 31.3 1.5 1.2e-07 31.3 1.5 2.4 1 1 1 2 2 2 2 ZIP Zinc transporter Longin PF13774.6 EKX42430.1 - 7.8e-19 67.5 0.0 1.2e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 EKX42430.1 - 6.6e-12 45.1 0.1 1.8e-11 43.7 0.0 1.7 2 0 0 2 2 2 1 Synaptobrevin Alpha_adaptinC2 PF02883.20 EKX42431.1 - 1.6e-09 38.0 1.5 4.1e-09 36.7 1.5 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.14 EKX42431.1 - 1e-07 32.2 2.4 1e-07 32.2 2.4 2.7 3 0 0 3 3 3 1 GAT domain VHS PF00790.19 EKX42431.1 - 0.00026 20.8 0.0 0.00071 19.4 0.0 1.7 1 0 0 1 1 1 1 VHS domain UIM PF02809.20 EKX42431.1 - 0.18 11.8 0.9 0.55 10.3 0.9 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif PCI PF01399.27 EKX42432.1 - 1.4e-19 70.5 0.6 7.3e-19 68.2 0.0 2.5 3 0 0 3 3 3 1 PCI domain RPN5_C PF18098.1 EKX42432.1 - 6.5e-14 51.7 5.3 1.8e-13 50.3 5.3 1.8 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain Noc2 PF03715.13 EKX42432.1 - 0.012 14.9 0.7 4.4 6.5 0.0 2.6 2 0 0 2 2 2 0 Noc2p family DUF2990 PF11693.8 EKX42432.1 - 0.15 12.2 0.0 0.42 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2990) DUF2247 PF10004.9 EKX42432.1 - 0.8 9.5 8.8 0.07 12.9 1.9 2.7 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2247) Cyclotide PF03784.13 EKX42433.1 - 0.12 12.5 0.3 0.97 9.6 0.1 2.0 2 0 0 2 2 2 0 Cyclotide family DUF1043 PF06295.12 EKX42434.1 - 0.03 14.3 0.2 1.5 8.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Ima1_N PF09779.9 EKX42434.1 - 0.19 12.6 2.6 0.53 11.1 2.6 1.8 1 1 0 1 1 1 0 Ima1 N-terminal domain DUF463 PF04317.12 EKX42434.1 - 0.21 10.4 1.0 0.29 10.0 1.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 Ion_trans PF00520.31 EKX42435.1 - 1.6e-132 440.2 79.4 6.3e-40 136.9 8.3 4.9 4 1 0 4 4 4 4 Ion transport protein PDZ_6 PF17820.1 EKX42435.1 - 0.0016 18.3 0.1 0.004 17.0 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX42435.1 - 0.0075 16.6 0.1 0.018 15.4 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX42435.1 - 0.0099 16.2 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain UPF0093 PF03653.13 EKX42435.1 - 0.92 9.7 7.5 0.38 11.0 0.2 3.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0093) PKD_channel PF08016.12 EKX42435.1 - 3.6 6.2 66.3 0.0095 14.6 0.6 7.9 8 1 1 9 9 9 0 Polycystin cation channel Str_synth PF03088.16 EKX42436.1 - 1.2e-14 54.1 0.0 4.2e-14 52.4 0.0 1.9 2 0 0 2 2 2 1 Strictosidine synthase SGL PF08450.12 EKX42436.1 - 3e-10 40.1 0.0 1.2e-09 38.2 0.0 1.9 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 EKX42436.1 - 0.00024 21.2 0.0 0.0036 17.5 0.0 2.5 3 0 0 3 3 3 1 Arylesterase LtuB PF17455.2 EKX42436.1 - 0.18 12.5 0.0 0.34 11.6 0.0 1.4 1 0 0 1 1 1 0 Late transcription unit B UPF0160 PF03690.13 EKX42437.1 - 2.6e-125 418.3 0.4 3e-125 418.1 0.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Carn_acyltransf PF00755.20 EKX42439.1 - 3.3e-148 494.9 0.0 3.9e-148 494.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase HTH_IclR PF09339.10 EKX42439.1 - 0.14 12.0 0.1 17 5.3 0.0 3.2 3 0 0 3 3 3 0 IclR helix-turn-helix domain SAP PF02037.27 EKX42441.1 - 2.6e-12 46.2 0.5 4.2e-12 45.5 0.5 1.4 1 0 0 1 1 1 1 SAP domain KH_1 PF00013.29 EKX42441.1 - 5.5e-08 32.5 0.0 8.5e-05 22.3 0.0 2.5 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 EKX42441.1 - 0.15 11.9 0.0 0.51 10.2 0.0 1.8 2 0 0 2 2 2 0 KH domain Thioredoxin PF00085.20 EKX42442.1 - 5.5e-25 87.3 0.8 9.4e-25 86.6 0.8 1.3 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 EKX42442.1 - 0.00058 19.8 0.0 0.00081 19.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 EKX42442.1 - 0.0022 18.2 0.0 0.0036 17.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EKX42442.1 - 0.003 18.0 0.1 0.024 15.1 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EKX42442.1 - 0.0099 15.7 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 EKX42442.1 - 0.014 15.1 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Redoxin Thioredoxin_8 PF13905.6 EKX42442.1 - 0.054 13.8 0.1 0.15 12.4 0.1 1.9 1 1 0 1 1 1 0 Thioredoxin-like DIM1 PF02966.16 EKX42442.1 - 0.078 12.8 0.3 0.11 12.3 0.3 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 Glutaredoxin PF00462.24 EKX42442.1 - 0.079 13.2 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 Glutaredoxin WD40 PF00400.32 EKX42443.1 - 8e-32 108.8 10.0 4.3e-07 30.5 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX42443.1 - 1.4e-12 47.7 0.1 5.1e-05 23.5 0.0 4.4 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EKX42443.1 - 0.0003 20.2 0.0 0.0014 18.0 0.0 2.0 1 1 0 1 1 1 1 WD40-like domain CPSF_A PF03178.15 EKX42443.1 - 0.0029 17.0 0.0 0.017 14.5 0.0 2.1 2 1 1 3 3 3 1 CPSF A subunit region TP1 PF02079.16 EKX42443.1 - 0.031 14.2 0.4 0.069 13.1 0.4 1.6 1 0 0 1 1 1 0 Nuclear transition protein 1 Cytochrom_D1 PF02239.16 EKX42443.1 - 0.05 12.1 0.0 0.19 10.2 0.1 1.9 3 0 0 3 3 3 0 Cytochrome D1 heme domain cNMP_binding PF00027.29 EKX42444.1 - 3.5e-11 43.0 0.0 6e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HATPase_c_3 PF13589.6 EKX42445.1 - 4.6e-09 36.2 0.0 1.4e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 EKX42445.1 - 0.0043 16.9 0.7 0.014 15.3 0.1 2.3 2 0 0 2 2 2 1 GHKL domain SMC_hinge PF06470.13 EKX42445.1 - 0.01 16.1 0.0 0.1 12.9 0.0 2.4 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain PolyG_pol PF01518.16 EKX42445.1 - 0.058 12.1 0.2 0.13 11.0 0.2 1.5 1 0 0 1 1 1 0 Sigma NS protein E6 PF00518.17 EKX42445.1 - 0.16 12.4 2.4 2.1 8.8 0.0 3.5 4 0 0 4 4 4 0 Early Protein (E6) DUF5082 PF16888.5 EKX42445.1 - 0.37 11.1 3.4 23 5.3 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Lebercilin PF15619.6 EKX42445.1 - 5.8 6.5 9.6 0.31 10.7 1.5 2.6 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease ANAPC4_WD40 PF12894.7 EKX42446.1 - 1.1e-15 57.7 0.3 0.00011 22.5 0.0 5.4 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EKX42446.1 - 1.9e-09 38.0 0.1 0.52 11.3 0.0 5.9 5 0 0 5 5 5 2 WD domain, G-beta repeat Nup160 PF11715.8 EKX42446.1 - 7.2e-06 24.9 0.0 0.00011 21.1 0.0 2.3 2 0 0 2 2 2 1 Nucleoporin Nup120/160 PD40 PF07676.12 EKX42446.1 - 2.9e-05 23.9 6.3 8 6.5 0.2 6.1 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Hira PF07569.11 EKX42446.1 - 0.091 12.5 0.0 0.8 9.4 0.0 2.3 2 0 0 2 2 2 0 TUP1-like enhancer of split Nucleoporin_N PF08801.11 EKX42446.1 - 0.12 11.1 0.0 49 2.5 0.0 3.0 3 0 0 3 3 3 0 Nup133 N terminal like Nop14 PF04147.12 EKX42446.1 - 0.16 10.1 2.9 0.27 9.4 2.9 1.2 1 0 0 1 1 1 0 Nop14-like family Ank_4 PF13637.6 EKX42447.1 - 3.4e-35 119.9 4.1 1.8e-12 47.5 0.1 3.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX42447.1 - 1e-30 106.1 1.1 7.1e-16 58.6 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX42447.1 - 9.2e-22 76.8 1.7 1.3e-08 34.9 0.1 4.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX42447.1 - 4.6e-21 72.7 0.2 8.2e-06 25.8 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EKX42447.1 - 9.3e-19 67.0 2.1 3.4e-07 30.4 0.4 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EKX42448.1 - 6.3e-15 55.3 1.6 2.7e-11 43.8 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX42448.1 - 4.7e-12 46.3 2.7 8.2e-12 45.5 1.0 1.8 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX42448.1 - 2.4e-10 39.7 0.2 0.00024 21.3 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EKX42448.1 - 5.3e-09 36.2 6.8 7.3e-07 29.4 1.4 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX42448.1 - 7.8e-08 32.4 6.3 0.0026 18.1 0.2 2.6 3 0 0 3 3 3 2 Ankyrin repeat DUF1521 PF07481.11 EKX42448.1 - 0.047 13.7 0.1 0.047 13.7 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1521) Formyl_trans_N PF00551.19 EKX42449.1 - 1.3e-28 100.0 0.0 2.9e-28 98.8 0.0 1.6 2 0 0 2 2 2 1 Formyl transferase Formyl_trans_C PF02911.18 EKX42449.1 - 7.6e-13 48.6 0.0 1.5e-11 44.4 0.0 2.4 1 1 0 1 1 1 1 Formyl transferase, C-terminal domain GST_N_3 PF13417.6 EKX42450.1 - 3e-15 56.4 0.0 6.4e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EKX42450.1 - 2.1e-13 50.3 0.0 5.5e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EKX42450.1 - 5.9e-11 42.2 2.5 6.3e-11 42.1 0.2 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EKX42450.1 - 5e-06 26.6 0.0 1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EKX42450.1 - 2.6e-05 24.4 0.0 5.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 EKX42450.1 - 5.6e-05 23.7 0.0 0.00011 22.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EKX42450.1 - 0.0011 19.7 0.1 0.025 15.3 0.1 3.1 2 1 1 3 3 3 1 Glutathione S-transferase N-terminal domain GST_C_3 PF14497.6 EKX42450.1 - 0.0027 17.9 0.0 0.006 16.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EKX42450.1 - 0.0081 16.4 0.1 0.021 15.0 0.1 1.8 1 0 0 1 1 1 1 Glutaredoxin EF-hand_7 PF13499.6 EKX42451.1 - 4.3e-13 49.5 7.2 7.9e-13 48.7 7.2 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX42451.1 - 9.7e-11 40.7 5.2 0.00013 21.7 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EKX42451.1 - 1e-10 40.3 8.5 3.3e-06 26.2 3.3 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX42451.1 - 1.6e-08 34.3 2.0 2e-08 34.0 0.9 1.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX42451.1 - 5.8e-06 25.6 4.6 0.00015 21.1 2.4 2.7 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.9 EKX42451.1 - 1.6e-05 25.2 1.3 2.5e-05 24.6 1.3 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EKX42451.1 - 0.008 16.5 1.4 0.034 14.5 0.8 2.1 1 1 1 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 EKX42451.1 - 0.052 13.5 3.5 1 9.4 3.6 2.2 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand PAPS_reduct PF01507.19 EKX42452.1 - 5.3e-44 150.3 0.1 9.5e-44 149.5 0.1 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Thioredoxin PF00085.20 EKX42452.1 - 2.7e-14 53.0 0.0 8.5e-14 51.4 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.6 EKX42452.1 - 0.066 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like DUF3000 PF11452.8 EKX42452.1 - 0.087 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3000) Pkinase PF00069.25 EKX42453.1 - 6.7e-67 225.6 0.0 1e-66 225.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX42453.1 - 5.6e-40 137.3 0.0 8e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX42453.1 - 0.018 14.4 0.1 0.061 12.7 0.0 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EKX42453.1 - 0.038 12.8 0.1 0.19 10.5 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase KA1 PF02149.19 EKX42453.1 - 0.051 13.4 0.1 0.24 11.2 0.1 2.1 1 1 0 1 1 1 0 Kinase associated domain 1 ACT_4 PF13291.6 EKX42453.1 - 0.43 11.2 3.7 24 5.6 0.1 3.3 3 0 0 3 3 3 0 ACT domain zf-Tim10_DDP PF02953.15 EKX42454.1 - 1.8e-16 59.5 6.0 2.2e-16 59.2 6.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger cNMP_binding PF00027.29 EKX42455.1 - 2.9e-12 46.5 0.0 6.6e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain AAA_16 PF13191.6 EKX42455.1 - 0.003 17.9 0.0 0.081 13.3 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EKX42455.1 - 0.0077 16.7 0.0 0.29 11.5 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Plasmodium_Vir PF05795.11 EKX42455.1 - 0.39 10.1 1.4 0.82 9.0 1.4 1.5 1 0 0 1 1 1 0 Plasmodium vivax Vir protein LRR_6 PF13516.6 EKX42457.1 - 7.3e-14 50.6 14.9 0.0051 16.8 1.0 5.8 6 0 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.7 EKX42457.1 - 6.7e-05 23.2 1.7 0.23 11.9 0.1 3.8 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) Rdx PF10262.9 EKX42457.1 - 0.049 13.8 0.1 0.15 12.3 0.1 1.8 1 0 0 1 1 1 0 Rdx family LRR_1 PF00560.33 EKX42457.1 - 0.051 14.1 2.3 9.1 7.3 0.0 4.1 4 1 0 4 4 4 0 Leucine Rich Repeat Peptidase_C2 PF00648.21 EKX42458.1 - 2.6e-66 223.7 0.0 4.2e-66 223.0 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 EKX42458.1 - 5.2e-29 101.3 0.0 7.7e-12 45.7 0.0 3.6 3 1 0 3 3 3 3 Calpain large subunit, domain III RWP-RK PF02042.15 EKX42459.1 - 9.4e-14 51.1 0.1 1.7e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX42460.1 - 5.8e-14 51.8 0.1 9.8e-14 51.1 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_6 PF01418.17 EKX42460.1 - 0.028 14.4 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family AP1AR PF15745.5 EKX42460.1 - 0.058 13.0 0.1 0.086 12.5 0.1 1.2 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein EF-hand_7 PF13499.6 EKX42461.1 - 3.1e-06 27.6 0.0 7.4e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX42461.1 - 0.00013 21.6 0.1 0.16 12.0 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EKX42461.1 - 0.0016 18.3 0.0 0.0035 17.2 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair DUF2475 PF10629.9 EKX42461.1 - 0.0032 17.6 0.0 0.0081 16.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2475) EF-hand_1 PF00036.32 EKX42461.1 - 0.086 12.4 0.1 0.45 10.2 0.1 2.1 2 0 0 2 2 2 0 EF hand SpoVAD PF07451.11 EKX42462.1 - 0.086 11.5 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) MFS_1 PF07690.16 EKX42463.1 - 1e-31 110.2 10.2 1.3e-31 109.8 10.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 EKX42463.1 - 0.0012 17.2 0.0 0.0031 15.9 0.0 1.6 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family ORC6 PF05460.13 EKX42464.1 - 0.056 12.7 46.3 0.046 13.0 18.4 2.6 2 1 0 3 3 3 0 Origin recognition complex subunit 6 (ORC6) SRP-alpha_N PF04086.13 EKX42464.1 - 2.5 7.9 48.4 0.22 11.4 21.6 2.3 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal HrpB7 PF09486.10 EKX42465.1 - 0.00061 20.2 5.4 0.00061 20.2 5.4 3.3 1 1 2 3 3 3 1 Bacterial type III secretion protein (HrpB7) PKcGMP_CC PF16808.5 EKX42465.1 - 0.0021 17.9 15.7 0.021 14.7 5.1 3.4 4 0 0 4 4 4 2 Coiled-coil N-terminus of cGMP-dependent protein kinase ATG16 PF08614.11 EKX42465.1 - 0.0029 17.8 8.9 0.0029 17.8 8.9 2.1 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.9 EKX42465.1 - 0.02 15.2 6.5 0.02 15.2 6.5 2.6 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_31 PF13614.6 EKX42465.1 - 0.034 14.1 0.7 0.069 13.1 0.7 1.5 1 0 0 1 1 1 0 AAA domain Biopterin_H PF00351.21 EKX42465.1 - 0.044 12.8 0.1 0.078 12.0 0.1 1.3 1 1 0 1 1 1 0 Biopterin-dependent aromatic amino acid hydroxylase MPS2 PF17060.5 EKX42465.1 - 0.046 13.0 16.8 0.23 10.7 13.3 2.3 1 1 1 2 2 2 0 Monopolar spindle protein 2 E2R135 PF11570.8 EKX42465.1 - 0.31 11.3 6.9 0.068 13.5 2.0 2.2 1 1 1 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 KASH_CCD PF14662.6 EKX42465.1 - 1.1 9.1 27.1 0.58 10.0 8.8 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF2284 PF10050.9 EKX42465.1 - 1.9 8.2 5.7 11 5.7 0.4 2.6 2 1 1 3 3 3 0 Predicted metal-binding protein (DUF2284) Spc7 PF08317.11 EKX42465.1 - 2.1 7.1 28.6 0.019 13.8 7.7 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein TMPIT PF07851.13 EKX42465.1 - 2.7 7.2 14.4 0.054 12.7 4.7 2.0 1 1 1 2 2 2 0 TMPIT-like protein Spc42p PF11544.8 EKX42465.1 - 3.4 7.7 15.4 1.4 8.9 2.4 3.7 2 2 2 4 4 4 0 Spindle pole body component Spc42p FUSC PF04632.12 EKX42465.1 - 3.4 6.1 12.0 4.4 5.7 12.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family AATF-Che1 PF13339.6 EKX42465.1 - 4.9 7.8 17.8 7.4 7.2 4.6 2.3 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Fib_alpha PF08702.10 EKX42465.1 - 6.9 6.9 17.8 6.5 6.9 9.2 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family ADIP PF11559.8 EKX42465.1 - 7.6 6.6 23.5 0.62 10.1 7.1 2.7 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 EKX42465.1 - 9.3 7.0 20.9 2.3 8.9 4.9 3.5 3 1 0 3 3 3 0 SlyX PI3_PI4_kinase PF00454.27 EKX42466.1 - 5.4e-33 114.8 0.0 3.5e-25 89.3 0.0 2.2 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 EKX42466.1 - 0.027 13.8 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) TrbL PF04610.14 EKX42467.1 - 0.16 11.7 6.5 0.32 10.7 6.5 1.4 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein KH_1 PF00013.29 EKX42468.1 - 8.3e-35 118.4 0.2 4.7e-16 58.4 0.0 2.3 2 0 0 2 2 2 2 KH domain SAP PF02037.27 EKX42468.1 - 5.6e-10 38.7 0.6 1.2e-09 37.7 0.6 1.6 1 0 0 1 1 1 1 SAP domain KH_2 PF07650.17 EKX42468.1 - 8.7e-10 38.3 1.4 0.00074 19.3 0.1 2.4 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 EKX42468.1 - 1e-08 34.9 1.8 0.0036 17.1 0.2 2.4 2 0 0 2 2 2 2 KH domain KH_5 PF13184.6 EKX42468.1 - 0.14 12.2 2.0 11 6.3 0.2 2.4 2 0 0 2 2 2 0 NusA-like KH domain PMT PF02366.18 EKX42469.1 - 0.47 10.0 19.7 0.01 15.5 12.6 1.8 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase WD40 PF00400.32 EKX42470.1 - 3e-24 84.8 13.5 1.5e-05 25.7 0.2 6.0 5 1 0 5 5 5 5 WD domain, G-beta repeat DUF3337 PF11816.8 EKX42470.1 - 1.4e-21 77.1 0.0 2.3e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) ANAPC4_WD40 PF12894.7 EKX42470.1 - 0.00024 21.3 0.3 1.1 9.6 0.1 3.6 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EKX42470.1 - 0.0005 18.8 1.2 0.0069 15.1 0.2 2.3 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EKX42470.1 - 0.0094 14.9 0.2 3.1 6.7 0.1 2.3 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Reg_prop PF07494.11 EKX42470.1 - 0.026 14.7 0.1 25 5.5 0.0 4.2 4 0 0 4 4 4 0 Two component regulator propeller PALB2_WD40 PF16756.5 EKX42470.1 - 0.19 10.6 2.2 7 5.5 0.1 2.6 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Methyltransf_23 PF13489.6 EKX42471.1 - 1.7e-15 57.3 0.0 2.7e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX42471.1 - 2.4e-11 44.1 0.0 4.5e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX42471.1 - 2.6e-11 44.1 0.0 5.9e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX42471.1 - 8.3e-10 39.3 0.0 1.5e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX42471.1 - 1.3e-09 37.7 0.0 2e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EKX42471.1 - 0.00032 20.5 0.0 0.00066 19.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EKX42471.1 - 0.029 14.2 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase PDZ_6 PF17820.1 EKX42473.1 - 1.6e-08 34.3 0.0 3.2e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX42473.1 - 2.9e-08 33.9 0.2 8.1e-08 32.5 0.2 1.7 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX42473.1 - 0.0003 20.7 0.0 0.0013 18.7 0.0 2.1 1 0 0 1 1 1 1 Tricorn protease PDZ domain PDZ PF00595.24 EKX42473.1 - 0.00086 19.6 0.1 0.0022 18.3 0.1 1.7 1 0 0 1 1 1 1 PDZ domain CENP-F_leu_zip PF10473.9 EKX42473.1 - 0.0065 16.5 14.7 0.0065 16.5 14.7 2.3 1 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF730 PF05325.11 EKX42473.1 - 0.033 14.2 1.7 0.033 14.2 1.7 3.9 2 2 2 4 4 4 0 Protein of unknown function (DUF730) ADIP PF11559.8 EKX42473.1 - 0.099 12.7 29.3 0.067 13.3 9.5 2.2 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding BRE1 PF08647.11 EKX42473.1 - 4.4 7.5 28.4 0.6 10.2 9.1 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase THOC7 PF05615.13 EKX42473.1 - 9.2 6.6 30.0 1.3 9.3 10.0 3.2 1 1 2 3 3 3 0 Tho complex subunit 7 Jnk-SapK_ap_N PF09744.9 EKX42474.1 - 2.3e-05 24.7 16.9 2.3e-05 24.7 16.9 3.0 1 1 0 2 2 2 1 JNK_SAPK-associated protein-1 BRE1 PF08647.11 EKX42474.1 - 0.043 13.9 1.3 0.043 13.9 1.3 3.8 2 2 2 4 4 4 0 BRE1 E3 ubiquitin ligase EnY2 PF10163.9 EKX42475.1 - 0.063 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Transcription factor e(y)2 BBS2_C PF14782.6 EKX42476.1 - 3.5e-131 437.9 11.7 6.7e-129 430.4 7.0 3.5 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 EKX42476.1 - 2.2e-37 127.4 0.8 8.7e-35 119.0 0.3 3.1 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.6 EKX42476.1 - 1.7e-30 105.0 0.0 2.2e-29 101.5 0.0 2.7 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, N-terminal VCBS PF13517.6 EKX42476.1 - 5.1e-07 30.2 2.1 0.00094 19.7 2.2 3.5 2 1 0 2 2 2 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Itfg2 PF15907.5 EKX42476.1 - 7.4e-07 28.5 0.6 0.013 14.6 0.0 3.3 1 1 2 3 3 3 2 Integrin-alpha FG-GAP repeat-containing protein 2 FG-GAP PF01839.23 EKX42476.1 - 2.3e-05 24.4 0.4 0.09 12.9 0.0 2.5 2 0 0 2 2 2 2 FG-GAP repeat ANAPC4_WD40 PF12894.7 EKX42476.1 - 0.0032 17.7 0.1 0.05 13.9 0.0 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Phage_Mu_Gp45 PF06890.12 EKX42476.1 - 0.025 14.3 0.0 9.5 6.0 0.0 3.1 2 1 1 3 3 3 0 Bacteriophage Mu Gp45 protein PTS_2-RNA PF01885.16 EKX42476.1 - 0.041 13.9 0.8 0.081 13.0 0.8 1.4 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family Mei5 PF10376.9 EKX42476.1 - 1.9 8.3 8.0 0.32 10.8 0.3 2.3 2 0 0 2 2 2 0 Double-strand recombination repair protein FG-GAP_2 PF14312.6 EKX42477.1 - 9.6e-13 48.2 6.0 0.012 15.9 0.2 5.2 5 0 0 5 5 5 4 FG-GAP repeat zf-RING_2 PF13639.6 EKX42478.1 - 4.7e-13 49.2 9.5 1.1e-12 48.0 9.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EKX42478.1 - 5.8e-09 35.5 6.2 1.4e-08 34.3 6.2 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EKX42478.1 - 1e-08 34.9 9.6 1e-08 34.9 9.6 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX42478.1 - 1.2e-07 31.5 8.3 2.5e-07 30.5 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX42478.1 - 1.2e-07 31.9 9.9 4.9e-07 29.9 9.9 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EKX42478.1 - 1.1e-06 28.4 7.6 2.5e-06 27.4 7.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EKX42478.1 - 1.6e-06 28.0 6.3 4e-06 26.7 6.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EKX42478.1 - 4.5e-06 26.4 6.2 4.5e-06 26.4 6.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX42478.1 - 0.00012 21.9 7.3 0.00012 21.9 7.3 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EKX42478.1 - 0.00012 22.1 3.9 0.00031 20.7 3.9 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EKX42478.1 - 0.0016 18.0 5.0 0.0016 18.0 5.0 1.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 EKX42478.1 - 0.0031 17.8 5.8 0.0031 17.8 5.8 2.2 2 0 0 2 2 2 1 RING-like domain Zf_RING PF16744.5 EKX42478.1 - 0.064 13.4 3.0 0.15 12.2 3.0 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger zf-C3H2C3 PF17122.5 EKX42478.1 - 0.08 13.0 1.7 0.24 11.5 1.7 1.8 1 0 0 1 1 1 0 Zinc-finger EphA2_TM PF14575.6 EKX42478.1 - 0.088 13.7 0.1 12 6.8 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain RINGv PF12906.7 EKX42478.1 - 0.23 11.6 8.1 0.78 9.9 8.1 1.9 1 1 0 1 1 1 0 RING-variant domain zf-HC5HC2H PF13771.6 EKX42478.1 - 0.37 11.1 4.2 1.9 8.8 3.8 2.2 1 1 1 2 2 2 0 PHD-like zinc-binding domain FANCL_C PF11793.8 EKX42478.1 - 0.42 10.8 7.9 3.4 7.9 7.9 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.8 EKX42478.1 - 0.67 9.8 3.6 1.8 8.4 3.6 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DnaJ_CXXCXGXG PF00684.19 EKX42480.1 - 0.0011 19.2 24.1 0.0011 19.2 24.1 2.3 1 1 1 2 2 2 2 DnaJ central domain Peptidase_S31 PF05578.12 EKX42481.1 - 0.036 13.6 0.0 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 Pestivirus NS3 polyprotein peptidase S31 DUF2937 PF11157.8 EKX42487.1 - 0.068 12.9 0.3 0.11 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) FKS1_dom1 PF14288.6 EKX42487.1 - 0.15 12.4 3.8 8.3 6.8 1.0 2.2 1 1 1 2 2 2 0 1,3-beta-glucan synthase subunit FKS1, domain-1 RNase_J_C PF17770.1 EKX42487.1 - 0.98 10.5 3.3 31 5.7 0.0 2.8 2 1 0 2 2 2 0 Ribonuclease J C-terminal domain TPR_1 PF00515.28 EKX42490.1 - 2.9e-38 128.1 0.7 1.7e-10 40.3 0.5 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 EKX42490.1 - 7.4e-32 106.9 0.6 8.1e-08 31.8 0.6 7.3 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 EKX42490.1 - 2.9e-24 83.2 0.7 0.00036 20.5 0.1 7.0 8 0 0 8 8 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 EKX42490.1 - 3.9e-22 78.6 0.2 7.1e-10 39.4 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX42490.1 - 6.2e-19 67.4 1.5 0.00024 20.7 0.1 6.9 2 1 5 7 7 6 4 TPR repeat TPR_19 PF14559.6 EKX42490.1 - 2e-18 66.7 4.5 4.6e-08 33.4 1.2 5.8 3 1 4 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX42490.1 - 5.5e-18 64.1 1.3 0.0017 19.0 0.0 6.9 3 2 3 7 7 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 EKX42490.1 - 2.3e-16 58.9 7.5 0.00015 21.9 0.0 6.7 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX42490.1 - 7.3e-16 58.2 4.2 4.5e-05 23.7 0.4 5.9 3 1 3 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 EKX42490.1 - 2.6e-11 42.7 0.5 0.054 13.5 0.0 6.5 5 1 1 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX42490.1 - 1.2e-10 41.5 16.0 0.0005 20.2 0.8 4.3 2 1 4 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EKX42490.1 - 2e-10 40.7 1.5 0.00071 19.7 0.1 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 EKX42490.1 - 3.6e-05 24.0 0.4 0.00074 19.8 0.4 2.8 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX42490.1 - 5e-05 23.7 3.0 11 6.9 0.1 6.4 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX42490.1 - 0.00029 20.6 0.5 1.7 8.6 0.1 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EKX42490.1 - 0.0014 18.3 0.4 0.35 10.5 0.2 3.3 2 1 1 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_15 PF13429.6 EKX42490.1 - 0.002 17.4 0.2 0.2 10.8 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX42490.1 - 0.0037 16.7 3.6 0.092 12.1 0.0 3.3 2 1 2 4 4 4 1 MalT-like TPR region FAT PF02259.23 EKX42490.1 - 0.0055 16.0 1.6 0.45 9.7 0.3 2.6 1 1 1 2 2 2 1 FAT domain TPR_21 PF09976.9 EKX42490.1 - 0.012 15.3 1.2 0.95 9.1 0.2 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat-like domain Fis1_TPR_C PF14853.6 EKX42490.1 - 0.049 13.7 1.5 24 5.1 0.0 4.0 4 1 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 EKX42490.1 - 0.056 13.5 0.1 3.1 7.9 0.0 3.4 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TOM20_plant PF06552.12 EKX42490.1 - 0.11 12.2 4.4 32 4.2 0.0 4.2 2 2 3 5 5 5 0 Plant specific mitochondrial import receptor subunit TOM20 BTAD PF03704.17 EKX42490.1 - 0.25 11.8 3.8 1.3 9.4 0.4 3.1 2 1 1 3 3 3 0 Bacterial transcriptional activator domain Metallophos_2 PF12850.7 EKX42491.1 - 1.3e-21 77.5 0.0 1.5e-21 77.3 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EKX42491.1 - 0.0013 19.2 0.3 0.033 14.7 0.2 2.2 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase RWP-RK PF02042.15 EKX42492.1 - 7.5e-15 54.6 0.0 1.3e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX42492.1 - 0.056 13.2 0.2 3.8 7.4 0.0 2.2 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family DUF2786 PF10979.8 EKX42493.1 - 0.001 18.9 0.2 0.0023 17.8 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2786) DUF1068 PF06364.12 EKX42493.1 - 0.009 15.9 0.8 0.14 12.0 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1068) COQ7 PF03232.13 EKX42493.1 - 0.051 13.4 0.4 0.11 12.3 0.4 1.5 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 OmpH PF03938.14 EKX42493.1 - 0.88 9.9 8.6 1.4 9.3 3.4 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF3530 PF12048.8 EKX42493.1 - 2.8 7.3 6.0 7.7 5.8 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3530) PseudoU_synth_1 PF01416.20 EKX42494.1 - 0.0021 18.5 0.1 0.6 10.6 0.0 3.0 2 1 1 3 3 3 2 tRNA pseudouridine synthase FG-GAP_2 PF14312.6 EKX42495.1 - 2.6e-13 50.0 5.2 0.003 17.8 0.2 4.5 4 0 0 4 4 4 3 FG-GAP repeat zf-RING_2 PF13639.6 EKX42495.1 - 9.9e-12 45.0 9.5 9.9e-12 45.0 9.5 7.2 9 0 0 9 9 9 1 Ring finger domain zf-RING_11 PF17123.5 EKX42495.1 - 2.2e-08 33.7 6.2 1.1e-07 31.5 6.2 2.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EKX42495.1 - 8.9e-08 31.9 9.6 8.9e-08 31.9 9.6 3.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX42495.1 - 5.5e-07 29.8 7.0 5.5e-07 29.8 7.0 3.7 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EKX42495.1 - 2.1e-06 27.5 8.3 2.1e-06 27.5 8.3 5.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX42495.1 - 2.2e-05 24.3 7.6 2.2e-05 24.3 7.6 5.6 5 0 0 5 5 5 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EKX42495.1 - 3.4e-05 23.8 6.3 3.4e-05 23.8 6.3 3.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EKX42495.1 - 4.2e-05 23.3 6.0 4.2e-05 23.3 6.0 8.4 9 1 0 9 9 9 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 EKX42495.1 - 0.2 12.0 22.0 0.027 14.8 5.8 6.0 4 0 0 4 4 4 0 RING-like domain MORN PF02493.20 EKX42496.1 - 2.9e-17 61.4 34.9 2.6e-08 33.3 0.6 5.6 7 0 0 7 7 7 3 MORN repeat DUF3048_C PF17479.2 EKX42496.1 - 0.021 15.2 5.1 1.3 9.4 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3048) C-terminal domain Glutaredoxin PF00462.24 EKX42498.1 - 9.5e-13 48.2 0.0 1.5e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 EKX42498.1 - 0.0068 16.8 0.0 0.01 16.2 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 EKX42498.1 - 0.0078 16.7 0.1 0.013 15.9 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EKX42498.1 - 0.048 13.4 0.0 0.059 13.1 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin TraF PF13728.6 EKX42498.1 - 0.084 12.7 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein zf-RanBP PF00641.18 EKX42499.1 - 0.00022 20.5 3.9 0.00065 19.0 3.9 1.7 1 1 0 1 1 1 1 Zn-finger in Ran binding protein and others Pkinase PF00069.25 EKX42500.1 - 2.3e-36 125.5 0.0 1.6e-35 122.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX42500.1 - 2.1e-17 63.3 0.0 3.1e-16 59.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX42500.1 - 0.0009 18.6 0.1 0.023 14.0 0.1 2.1 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EKX42500.1 - 0.0031 16.9 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_2 PF13639.6 EKX42502.1 - 5.9e-13 48.9 14.3 1.3e-12 47.8 5.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EKX42502.1 - 5.9e-08 32.9 7.2 5.9e-08 32.9 7.2 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EKX42502.1 - 2.1e-07 30.7 7.1 2.1e-07 30.7 7.1 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EKX42502.1 - 3.6e-07 30.1 4.2 4.8e-06 26.5 0.9 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 EKX42502.1 - 2.7e-06 27.0 3.7 3.8e-06 26.5 1.2 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EKX42502.1 - 2.9e-06 27.0 12.1 0.0002 21.1 5.1 2.9 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX42502.1 - 7.9e-06 25.6 1.9 7.9e-06 25.6 1.9 2.5 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EKX42502.1 - 9.9e-06 25.3 3.8 9.9e-06 25.3 3.8 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX42502.1 - 3.3e-05 23.8 0.8 3.3e-05 23.8 0.8 2.3 3 1 0 3 3 1 1 RING-type zinc-finger zinc_ribbon_9 PF14369.6 EKX42502.1 - 0.00011 22.3 3.2 0.00011 22.3 3.2 2.7 3 0 0 3 3 2 1 zinc-ribbon zf-RING_5 PF14634.6 EKX42502.1 - 0.00066 19.6 5.3 0.00066 19.6 5.3 3.1 2 2 1 3 3 3 1 zinc-RING finger domain RINGv PF12906.7 EKX42502.1 - 0.0018 18.4 2.2 0.0018 18.4 2.2 2.5 2 1 0 2 2 2 1 RING-variant domain HypA PF01155.19 EKX42502.1 - 0.0019 18.2 0.2 0.0019 18.2 0.2 2.6 2 1 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1272 PF06906.11 EKX42502.1 - 0.0021 18.1 0.2 0.0021 18.1 0.2 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1272) Zn_ribbon_17 PF17120.5 EKX42502.1 - 0.0023 17.5 4.7 0.0023 17.5 4.7 2.5 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type NOB1_Zn_bind PF08772.11 EKX42502.1 - 0.0036 17.4 0.1 0.0098 16.0 0.1 1.7 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like Rad50_zn_hook PF04423.14 EKX42502.1 - 0.0045 16.8 2.3 0.22 11.4 0.1 2.8 3 0 0 3 3 2 1 Rad50 zinc hook motif Zn-ribbon_8 PF09723.10 EKX42502.1 - 0.005 16.9 1.4 0.005 16.9 1.4 2.9 3 0 0 3 3 3 1 Zinc ribbon domain zf-TFIIB PF13453.6 EKX42502.1 - 0.016 14.5 5.6 1.2 8.5 0.2 3.4 3 0 0 3 3 3 0 Transcription factor zinc-finger Ribosomal_L37ae PF01780.19 EKX42502.1 - 0.017 15.2 1.0 0.054 13.6 0.1 2.4 2 1 0 2 2 2 0 Ribosomal L37ae protein family OrfB_Zn_ribbon PF07282.11 EKX42502.1 - 0.17 11.8 6.9 0.42 10.6 0.5 3.1 3 0 0 3 3 3 0 Putative transposase DNA-binding domain zf-C4_Topoisom PF01396.19 EKX42502.1 - 0.27 11.0 0.0 0.27 11.0 0.0 2.8 3 0 0 3 3 2 0 Topoisomerase DNA binding C4 zinc finger zf_Rg PF17915.1 EKX42502.1 - 0.57 9.6 0.0 0.57 9.6 0.0 2.4 3 0 0 3 3 2 0 Reverse gyrase zinc finger PHD PF00628.29 EKX42502.1 - 0.6 10.0 11.1 0.11 12.4 2.2 3.0 2 2 2 4 4 4 0 PHD-finger zf-Nse PF11789.8 EKX42502.1 - 0.75 9.7 4.8 0.22 11.4 1.3 1.9 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit DUF2072 PF09845.9 EKX42502.1 - 2.1 8.6 5.1 0.23 11.7 0.8 1.8 2 1 0 2 2 1 0 Zn-ribbon containing protein zf-H2C2_2 PF13465.6 EKX42502.1 - 3.1 8.4 8.3 13 6.4 0.0 3.9 4 0 0 4 4 4 0 Zinc-finger double domain DZR PF12773.7 EKX42502.1 - 3.2 7.8 9.3 1.3 9.1 0.4 2.8 2 1 0 2 2 2 0 Double zinc ribbon FANCL_C PF11793.8 EKX42502.1 - 3.2 8.0 9.1 0.78 10.0 3.9 2.6 2 1 1 3 3 2 0 FANCL C-terminal domain DnaJ_CXXCXGXG PF00684.19 EKX42502.1 - 3.3 8.1 8.4 1.3 9.5 0.2 3.1 2 1 2 4 4 4 0 DnaJ central domain zf-H2C2_5 PF13909.6 EKX42502.1 - 3.5 7.4 6.5 0.2 11.5 1.1 1.8 2 0 0 2 2 1 0 C2H2-type zinc-finger domain zinc-ribbons_6 PF07191.12 EKX42502.1 - 4.2 7.4 9.5 1.5 8.9 0.4 2.8 2 1 0 2 2 2 0 zinc-ribbons FAD_binding_3 PF01494.19 EKX42504.1 - 1.8e-14 53.8 0.2 1.1e-13 51.2 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EKX42504.1 - 2.9e-11 43.1 0.0 3.8e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 EKX42504.1 - 1e-05 25.3 0.0 0.0029 17.3 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EKX42504.1 - 0.00015 21.9 0.0 0.00031 20.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EKX42504.1 - 0.00049 20.6 0.1 0.0021 18.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EKX42504.1 - 0.00063 18.6 0.0 0.0011 17.8 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 EKX42504.1 - 0.0032 16.7 0.0 0.046 12.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EKX42504.1 - 0.0052 16.7 0.0 0.0082 16.0 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 EKX42504.1 - 0.021 14.2 0.3 0.063 12.6 0.3 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EKX42504.1 - 0.022 14.1 0.1 0.034 13.5 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 EKX42504.1 - 0.029 13.4 0.0 0.24 10.4 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 EKX42504.1 - 0.094 12.0 0.0 2.1 7.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EKX42504.1 - 0.18 10.6 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Cys_rich_KTR PF14205.6 EKX42505.1 - 0.11 12.4 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Cysteine-rich KTR CpXC PF14353.6 EKX42505.1 - 0.12 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 CpXC protein DUF5528 PF17666.1 EKX42505.1 - 0.2 11.6 0.0 0.25 11.3 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5528) DUF676 PF05057.14 EKX42506.1 - 0.00066 19.3 0.0 0.0049 16.4 0.0 2.3 4 0 0 4 4 4 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EKX42506.1 - 0.01 16.4 1.3 0.034 14.7 1.4 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EKX42506.1 - 0.044 13.0 0.0 0.094 12.0 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EKX42506.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold LCAT PF02450.15 EKX42506.1 - 0.091 11.9 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF915 PF06028.11 EKX42506.1 - 0.18 11.1 0.0 0.51 9.6 0.0 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) HORMA PF02301.18 EKX42507.1 - 2.6e-40 138.3 0.1 3e-40 138.1 0.1 1.0 1 0 0 1 1 1 1 HORMA domain TraD_N PF12615.8 EKX42507.1 - 0.0084 16.9 0.1 5.1 7.9 0.0 2.5 2 0 0 2 2 2 2 F sex factor protein N terminal WD40 PF00400.32 EKX42508.1 - 1.2e-13 51.2 1.7 0.0001 23.0 0.2 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat AAA_16 PF13191.6 EKX42508.1 - 1.3e-06 28.9 4.9 1.5e-06 28.7 0.1 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EKX42508.1 - 3.7e-05 24.0 0.1 0.00013 22.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain ANAPC4_WD40 PF12894.7 EKX42508.1 - 0.00026 21.2 0.0 1.5 9.1 0.0 3.7 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain T2SSE PF00437.20 EKX42508.1 - 0.00046 19.3 0.0 0.00082 18.5 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_18 PF13238.6 EKX42508.1 - 0.0019 18.7 0.0 0.0019 18.7 0.0 3.0 3 0 0 3 3 1 1 AAA domain AAA_7 PF12775.7 EKX42508.1 - 0.027 14.0 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region UvrD-helicase PF00580.21 EKX42508.1 - 0.042 13.4 0.1 0.096 12.2 0.1 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain NTPase_1 PF03266.15 EKX42508.1 - 0.043 13.7 0.1 0.082 12.8 0.1 1.4 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 EKX42508.1 - 0.062 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 EKX42508.1 - 0.063 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ge1_WD40 PF16529.5 EKX42508.1 - 0.065 12.2 0.0 3.7 6.4 0.0 3.0 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TniB PF05621.11 EKX42508.1 - 0.08 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_25 PF13481.6 EKX42508.1 - 0.082 12.5 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF1179 PF06678.11 EKX42508.1 - 0.1 12.6 0.2 0.37 10.8 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) AAA_24 PF13479.6 EKX42508.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EKX42508.1 - 0.13 11.4 1.4 0.26 10.4 0.0 2.2 3 0 0 3 3 3 0 NB-ARC domain ResIII PF04851.15 EKX42508.1 - 0.15 12.0 0.0 0.53 10.3 0.0 1.9 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EKX42508.1 - 0.16 12.3 1.5 0.25 11.7 0.0 2.0 2 0 0 2 2 1 0 AAA domain ATP_bind_1 PF03029.17 EKX42508.1 - 0.32 10.7 0.7 0.55 10.0 0.1 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Stealth_CR3 PF17102.5 EKX42509.1 - 0.14 12.1 0.1 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 Stealth protein CR3, conserved region 3 V_ATPase_I PF01496.19 EKX42511.1 - 0.019 12.9 10.6 0.026 12.5 10.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.11 EKX42511.1 - 0.021 15.0 19.6 0.03 14.6 19.6 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) ABC_tran_CTD PF16326.5 EKX42511.1 - 0.022 15.0 23.1 0.44 10.8 8.1 3.8 3 1 0 3 3 3 0 ABC transporter C-terminal domain Exonuc_VII_L PF02601.15 EKX42511.1 - 0.041 13.5 15.0 0.058 13.0 15.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit HSBP1 PF06825.12 EKX42511.1 - 0.11 12.4 2.1 0.55 10.1 0.3 2.8 2 0 0 2 2 2 0 Heat shock factor binding protein 1 ALMT PF11744.8 EKX42511.1 - 0.13 11.0 11.1 0.17 10.7 11.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DASH_Dad4 PF08650.10 EKX42511.1 - 0.25 11.3 7.2 0.43 10.6 0.3 3.2 2 1 2 4 4 3 0 DASH complex subunit Dad4 DNA_pack_N PF02500.15 EKX42511.1 - 0.33 10.7 4.6 0.43 10.4 4.6 1.3 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus Sugarporin_N PF11471.8 EKX42511.1 - 0.33 10.9 8.2 0.29 11.1 1.9 2.9 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Syntaxin-6_N PF09177.11 EKX42511.1 - 0.4 11.3 13.8 2.1 8.9 10.7 2.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Fib_alpha PF08702.10 EKX42511.1 - 0.59 10.3 18.7 0.22 11.7 10.7 2.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family YojJ PF10372.9 EKX42511.1 - 0.63 10.2 9.4 22 5.3 0.5 4.3 2 2 3 5 5 5 0 Bacterial membrane-spanning protein N-terminus FapA PF03961.13 EKX42511.1 - 1 7.9 22.0 0.48 9.0 7.5 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A CorA PF01544.18 EKX42511.1 - 1.9 7.8 10.5 3 7.1 10.3 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Plk4_PB2 PF18409.1 EKX42511.1 - 1.9 9.2 8.0 17 6.1 7.1 2.6 1 1 0 1 1 1 0 Polo-like Kinase 4 Polo Box 2 PSI_PsaF PF02507.15 EKX42511.1 - 2.4 8.0 5.7 0.93 9.3 1.3 2.2 1 1 0 2 2 2 0 Photosystem I reaction centre subunit III NPV_P10 PF05531.12 EKX42511.1 - 2.7 8.5 8.5 1.3 9.5 0.6 3.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein CSN5_C PF18323.1 EKX42511.1 - 2.8 8.9 14.9 7.3 7.6 6.7 2.4 1 1 1 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain DUF3037 PF11236.8 EKX42511.1 - 3.6 8.1 10.1 4.9 7.6 4.7 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3037) TMF_DNA_bd PF12329.8 EKX42511.1 - 3.8 7.6 23.3 0.64 10.1 4.9 3.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.9 EKX42511.1 - 3.9 6.5 17.4 5.7 5.9 17.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sulfatase_C PF14707.6 EKX42511.1 - 6.3 7.6 7.5 7.8 7.3 2.2 2.5 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase FlaC_arch PF05377.11 EKX42511.1 - 6.5 7.2 10.0 20 5.7 2.9 3.4 3 1 0 3 3 2 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.20 EKX42511.1 - 7.1 6.6 26.0 1.1 9.2 18.3 3.3 1 1 1 2 2 2 0 Prefoldin subunit UPF0242 PF06785.11 EKX42511.1 - 7.1 6.7 26.1 26 4.9 26.1 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Fmp27_WPPW PF10359.9 EKX42511.1 - 8.1 5.2 18.7 1.1 8.0 14.0 1.7 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Snapin_Pallidin PF14712.6 EKX42511.1 - 8.2 6.9 19.7 0.24 11.8 7.1 3.2 2 1 1 3 3 3 0 Snapin/Pallidin Ion_trans PF00520.31 EKX42514.1 - 1.2e-21 77.0 31.3 3e-15 56.1 12.8 2.6 2 1 0 2 2 2 2 Ion transport protein SieB PF14163.6 EKX42514.1 - 0.1 12.1 0.1 0.1 12.1 0.1 2.0 2 0 0 2 2 2 0 Super-infection exclusion protein B UPF0542 PF15086.6 EKX42514.1 - 0.11 12.4 0.4 1.3 9.0 0.2 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 DUF3481 PF11980.8 EKX42514.1 - 0.12 12.1 0.2 0.45 10.3 0.0 2.1 2 0 0 2 2 2 0 C-terminal domain of neuropilin glycoprotein Phage_holin_4_1 PF05105.12 EKX42514.1 - 0.3 11.3 4.4 0.5 10.5 0.0 3.3 3 0 0 3 3 3 0 Bacteriophage holin family Imm52 PF15579.6 EKX42515.1 - 0.12 12.2 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 52 Sld5 PF05916.11 EKX42515.1 - 0.16 12.4 1.7 1.4 9.4 0.8 2.2 1 1 1 2 2 2 0 GINS complex protein Peptidase_C14 PF00656.22 EKX42516.1 - 0.0003 20.8 0.1 0.0014 18.7 0.0 2.0 2 1 0 2 2 2 1 Caspase domain DM PF00751.18 EKX42516.1 - 0.039 13.8 0.5 0.095 12.6 0.5 1.6 1 0 0 1 1 1 0 DM DNA binding domain DUF1896 PF08989.10 EKX42516.1 - 0.11 12.6 0.1 1.8 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1896) Peptidase_M41 PF01434.18 EKX42517.1 - 1.8e-67 226.9 0.2 1.8e-67 226.9 0.2 1.9 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 EKX42517.1 - 1.2e-43 148.7 0.0 6.4e-43 146.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EKX42517.1 - 1.3e-09 37.7 0.1 3.2e-09 36.5 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EKX42517.1 - 9.3e-07 28.7 0.0 1.3e-05 25.0 0.0 2.5 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EKX42517.1 - 1e-05 25.6 0.0 0.00014 21.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EKX42517.1 - 2.2e-05 23.8 0.0 5.1e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 EKX42517.1 - 0.00014 22.3 2.0 0.00073 20.0 0.4 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EKX42517.1 - 0.0012 19.1 0.4 0.11 12.8 0.0 2.8 1 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 EKX42517.1 - 0.0014 17.9 0.0 0.0032 16.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 EKX42517.1 - 0.0023 18.1 0.1 0.012 15.7 0.0 2.2 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EKX42517.1 - 0.0043 16.8 0.0 0.013 15.2 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 EKX42517.1 - 0.0082 16.3 0.2 0.044 13.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EKX42517.1 - 0.011 15.1 0.6 0.039 13.3 0.1 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 EKX42517.1 - 0.012 14.7 0.2 0.14 11.2 0.1 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 TsaE PF02367.17 EKX42517.1 - 0.021 14.8 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EKX42517.1 - 0.029 14.9 0.0 0.082 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2730 PF10805.8 EKX42517.1 - 0.032 14.3 0.2 0.075 13.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) AAA_19 PF13245.6 EKX42517.1 - 0.035 14.5 2.2 6.2 7.1 0.6 2.7 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EKX42517.1 - 0.043 13.5 0.1 0.62 9.7 0.0 2.5 2 1 0 3 3 3 0 Sigma-54 interaction domain AAA_28 PF13521.6 EKX42517.1 - 0.052 13.8 0.1 0.27 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EKX42517.1 - 0.098 12.4 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EKX42517.1 - 0.15 12.0 0.5 1.3 8.9 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 EKX42517.1 - 0.17 12.4 1.1 9 6.7 0.1 2.7 3 0 0 3 3 3 0 AAA domain Metal_resist PF13801.6 EKX42517.1 - 0.27 11.4 2.4 0.2 11.8 0.3 1.9 2 0 0 2 2 1 0 Heavy-metal resistance Enkurin PF13864.6 EKX42517.1 - 0.34 11.4 4.3 1.1 9.8 4.3 1.9 1 1 0 1 1 1 0 Calmodulin-binding AAA_11 PF13086.6 EKX42517.1 - 0.4 10.4 2.9 0.89 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EKX42517.1 - 0.51 9.6 4.4 1.4 8.2 0.0 3.1 3 1 1 4 4 4 0 KaiC FliD_N PF02465.18 EKX42517.1 - 1.5 9.5 6.5 0.33 11.7 0.9 2.6 3 0 0 3 3 2 0 Flagellar hook-associated protein 2 N-terminus ABC_tran_CTD PF16326.5 EKX42517.1 - 4.7 7.5 9.8 0.32 11.3 1.6 3.0 3 0 0 3 3 3 0 ABC transporter C-terminal domain Defensin_beta PF00711.19 EKX42518.1 - 7.9 6.6 13.7 6.8 6.8 0.7 3.0 3 0 0 3 3 3 0 Beta defensin RRM_1 PF00076.22 EKX42520.1 - 4.9e-14 51.9 0.1 9e-14 51.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EKX42520.1 - 0.0011 19.0 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Condensin2nSMC PF12422.8 EKX42521.1 - 2e-52 177.4 0.2 9.5e-52 175.1 0.2 2.3 1 0 0 1 1 1 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.22 EKX42521.1 - 1.4e-05 24.9 6.0 0.36 11.2 0.0 6.3 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 EKX42521.1 - 0.0018 18.4 1.2 0.55 10.3 0.0 3.9 2 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EKX42521.1 - 0.0053 15.4 7.0 0.1 11.2 2.4 2.6 2 1 1 3 3 3 2 Adaptin N terminal region RXT2_N PF08595.11 EKX42521.1 - 0.0097 15.9 0.4 0.0097 15.9 0.4 2.3 3 0 0 3 3 3 1 RXT2-like, N-terminal FAM176 PF14851.6 EKX42521.1 - 0.024 14.3 0.5 0.024 14.3 0.5 3.1 3 1 0 4 4 4 0 FAM176 family Caskin-tail PF16632.5 EKX42521.1 - 0.025 15.0 1.2 0.1 13.1 0.6 2.4 2 0 0 2 2 2 0 C-terminal region of Caskin Pox_Ag35 PF03286.14 EKX42521.1 - 0.42 10.4 5.2 0.42 10.4 0.9 2.6 2 0 0 2 2 2 0 Pox virus Ag35 surface protein SelK_SelG PF10961.8 EKX42521.1 - 0.94 10.1 3.3 72 4.1 1.6 3.2 3 0 0 3 3 3 0 Selenoprotein SelK_SelG DUF5090 PF17009.5 EKX42522.1 - 0.33 10.9 9.5 0.39 10.7 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) SHR3_chaperone PF08229.11 EKX42522.1 - 1.5 7.8 7.1 0.65 8.9 4.4 1.7 2 0 0 2 2 2 0 ER membrane protein SH3 Yae1_N PF09811.9 EKX42524.1 - 5.3e-06 26.0 10.5 0.097 12.4 0.2 5.1 4 1 1 5 5 5 4 Essential protein Yae1, N terminal TPT PF03151.16 EKX42526.1 - 1.2e-06 28.1 17.9 1.5e-06 27.8 17.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family SR-25 PF10500.9 EKX42527.1 - 3.5e-18 66.1 23.5 4.5e-18 65.7 23.5 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein AF-4 PF05110.13 EKX42527.1 - 0.34 8.9 14.4 0.38 8.8 14.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SRP-alpha_N PF04086.13 EKX42527.1 - 0.53 10.2 23.0 0.74 9.7 23.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Rtf2 PF04641.12 EKX42527.1 - 0.94 8.8 18.5 1.4 8.2 18.5 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger PepSY_TM_like_2 PF16357.5 EKX42527.1 - 1.4 8.8 4.4 3.8 7.4 4.5 1.8 1 1 0 1 1 1 0 Putative PepSY_TM-like Presenilin PF01080.17 EKX42527.1 - 1.6 7.4 12.5 1.7 7.3 12.5 1.1 1 0 0 1 1 1 0 Presenilin Sin_N PF04801.13 EKX42527.1 - 2.2 7.4 14.5 2.3 7.3 14.5 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region Sec62 PF03839.16 EKX42527.1 - 3 7.3 12.9 4.2 6.8 12.9 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 CRT10 PF08728.10 EKX42527.1 - 4.1 5.5 5.9 4.4 5.4 5.9 1.0 1 0 0 1 1 1 0 CRT10 GREB1 PF15782.5 EKX42527.1 - 4.4 4.3 7.7 4.7 4.2 7.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CDC45 PF02724.14 EKX42527.1 - 4.9 5.3 23.4 6.1 5.0 23.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2151 PF10221.9 EKX42527.1 - 5.4 5.5 13.2 6.2 5.3 13.2 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator DUF21 PF01595.20 EKX42528.1 - 2.1e-29 102.5 3.2 2.1e-29 102.5 3.2 1.8 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EKX42528.1 - 6.4e-17 61.7 3.6 1.4e-09 38.2 0.2 2.7 2 0 0 2 2 2 2 CBS domain CorC_HlyC PF03471.17 EKX42528.1 - 1.8e-12 47.0 0.0 5e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Transporter associated domain GED PF02212.18 EKX42528.1 - 0.14 12.3 0.1 0.33 11.1 0.1 1.5 1 0 0 1 1 1 0 Dynamin GTPase effector domain OFeT_1 PF16955.5 EKX42530.1 - 0.0056 16.4 1.0 0.0079 15.9 1.0 1.2 1 0 0 1 1 1 1 Ferrous iron uptake permease, iron-lead transporter Strep_SA_rep PF06696.11 EKX42530.1 - 0.053 13.5 0.6 0.091 12.8 0.6 1.3 1 0 0 1 1 1 0 Streptococcal surface antigen repeat SAM_2 PF07647.17 EKX42531.1 - 6.2e-11 42.2 0.0 1e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EKX42531.1 - 1.4e-10 41.4 0.0 2.3e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 EKX42531.1 - 0.019 15.2 0.1 0.041 14.1 0.1 1.5 1 0 0 1 1 1 0 Ste50p, sterile alpha motif OFeT_1 PF16955.5 EKX42531.1 - 0.029 14.1 0.9 0.06 13.0 0.9 1.5 1 0 0 1 1 1 0 Ferrous iron uptake permease, iron-lead transporter DUF2269 PF10027.9 EKX42531.1 - 0.035 14.1 1.2 7.1 6.7 0.0 2.9 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2269) Pox_Ag35 PF03286.14 EKX42532.1 - 0.54 10.0 4.0 1.4 8.7 4.0 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM176 PF14851.6 EKX42532.1 - 1.3 8.6 5.3 4.4 7.0 5.3 1.9 1 0 0 1 1 1 0 FAM176 family Myc_N PF01056.18 EKX42532.1 - 7.9 6.3 9.3 16 5.3 9.3 1.4 1 0 0 1 1 1 0 Myc amino-terminal region WD40 PF00400.32 EKX42533.1 - 6e-07 30.1 3.2 0.067 14.1 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat HSP70 PF00012.20 EKX42534.1 - 2.5e-259 861.5 12.7 2.9e-259 861.3 12.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EKX42534.1 - 1.7e-17 63.3 0.4 1.2e-15 57.2 0.1 2.3 2 0 0 2 2 2 1 MreB/Mbl protein CPSase_L_D2 PF02786.17 EKX42534.1 - 0.0014 18.1 0.2 0.004 16.7 0.2 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Hydantoinase_A PF01968.18 EKX42534.1 - 0.0016 17.7 2.0 0.073 12.3 0.2 2.7 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase FtsA PF14450.6 EKX42534.1 - 0.002 18.5 3.5 1.6 9.2 0.2 3.2 3 1 0 3 3 3 2 Cell division protein FtsA DDR PF08841.10 EKX42534.1 - 0.03 13.3 0.2 0.19 10.7 0.1 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.16 EKX42534.1 - 0.052 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DUF3289 PF11692.8 EKX42534.1 - 0.11 12.1 3.9 0.32 10.6 2.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3289) Radial_spoke_3 PF06098.11 EKX42534.1 - 0.15 11.3 12.6 0.013 14.8 7.2 1.8 2 0 0 2 2 2 0 Radial spoke protein 3 Vps35 PF03635.17 EKX42534.1 - 0.23 9.9 1.4 11 4.3 0.0 2.1 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 35 HU-CCDC81_bac_2 PF18175.1 EKX42534.1 - 0.29 11.0 3.5 21 5.1 0.2 3.5 3 0 0 3 3 3 0 CCDC81-like prokaryotic HU domain 2 Colicin_immun PF09204.10 EKX42534.1 - 0.94 10.0 9.0 0.42 11.2 4.9 2.4 3 0 0 3 3 2 0 Bacterial self-protective colicin-like immunity GLE1 PF07817.13 EKX42534.1 - 3.2 6.9 5.5 4.9 6.3 0.0 2.6 3 0 0 3 3 3 0 GLE1-like protein ISG65-75 PF11727.8 EKX42534.1 - 6.6 5.9 14.7 11 5.2 8.3 2.4 2 0 0 2 2 2 0 Invariant surface glycoprotein LRR_8 PF13855.6 EKX42536.1 - 7.9e-52 172.9 81.9 3.5e-12 45.9 0.2 10.5 4 2 7 11 11 11 11 Leucine rich repeat LRR_4 PF12799.7 EKX42536.1 - 9.1e-40 134.0 80.4 1.2e-07 31.9 2.9 12.7 6 3 6 14 14 14 14 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX42536.1 - 1.3e-07 31.3 29.7 0.1 12.1 0.3 6.1 2 2 2 6 6 6 5 Leucine-rich repeat LRR_1 PF00560.33 EKX42536.1 - 1.5e-06 27.9 72.4 4.2 8.3 0.0 17.1 16 3 1 17 17 17 7 Leucine Rich Repeat LRR_5 PF13306.6 EKX42536.1 - 0.056 13.4 0.0 5.4 7.0 0.0 3.2 3 0 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) PET PF06297.14 EKX42537.1 - 0.025 14.9 0.7 0.19 12.0 0.4 2.6 2 0 0 2 2 2 0 PET Domain Peptidase_S64 PF08192.11 EKX42537.1 - 5.9 5.3 16.7 8.2 4.8 16.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 WD40 PF00400.32 EKX42539.1 - 6.2e-12 45.8 10.1 0.00016 22.4 0.1 5.7 5 1 1 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX42539.1 - 1e-06 28.9 0.0 0.03 14.6 0.0 4.2 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EKX42539.1 - 0.0049 16.8 0.5 0.019 14.8 0.4 2.1 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Argos PF11581.8 EKX42539.1 - 0.057 13.4 1.6 0.11 12.6 0.3 2.0 2 0 0 2 2 2 0 Antagonist of EGFR signalling, Argos PP_kinase_C PF13090.6 EKX42539.1 - 0.094 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 2 P53_C PF11619.8 EKX42539.1 - 0.11 12.6 0.0 0.42 10.7 0.0 2.0 1 0 0 1 1 1 0 Transcription factor P53 - C terminal domain LRR_8 PF13855.6 EKX42539.1 - 0.18 11.6 0.2 0.39 10.5 0.0 1.6 2 0 0 2 2 2 0 Leucine rich repeat Ribosomal_L7Ae PF01248.26 EKX42540.1 - 3.9e-27 93.8 0.8 5.3e-27 93.4 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EKX42540.1 - 0.0011 19.0 0.0 0.0012 18.9 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 DEAD_2 PF06733.15 EKX42541.1 - 8.1e-44 149.3 0.1 2.6e-43 147.7 0.1 2.0 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 EKX42541.1 - 2e-32 112.7 0.0 3.7e-29 102.1 0.0 3.0 1 1 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 EKX42541.1 - 0.00034 20.3 0.3 0.031 13.9 0.0 2.4 2 0 0 2 2 2 1 Helical and beta-bridge domain DEAD PF00270.29 EKX42541.1 - 0.0012 18.6 0.0 0.028 14.2 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EKX42541.1 - 0.0013 18.8 0.0 0.12 12.4 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Med24_N PF11277.8 EKX42541.1 - 0.022 12.9 0.0 0.036 12.1 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal PcF PF09461.10 EKX42541.1 - 1 9.8 6.4 20 5.6 0.2 3.3 2 0 0 2 2 2 0 Phytotoxin PcF protein CDC45 PF02724.14 EKX42541.1 - 1.1 7.4 12.5 0.058 11.7 4.0 2.4 3 0 0 3 3 3 0 CDC45-like protein CEP19 PF14933.6 EKX42542.1 - 6.3e-20 72.1 18.6 2.4e-14 54.0 18.6 2.7 1 1 0 1 1 1 1 CEP19-like protein CDC27 PF09507.10 EKX42542.1 - 0.76 9.1 30.8 0.051 13.0 26.1 1.5 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Membralin PF09746.9 EKX42542.1 - 8.3 5.3 5.9 11 4.9 5.9 1.4 1 0 0 1 1 1 0 Tumour-associated protein LRR_9 PF14580.6 EKX42543.1 - 1.4e-19 70.3 3.2 1.5e-19 70.1 3.2 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EKX42543.1 - 2.7e-09 37.2 12.6 8e-06 26.1 4.6 3.4 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX42543.1 - 1.4e-08 34.4 14.7 5.8e-07 29.2 8.6 2.4 1 1 2 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 EKX42543.1 - 0.069 13.2 7.5 0.29 11.3 0.0 4.0 5 0 0 5 5 5 0 Leucine Rich repeat Btz PF09405.10 EKX42544.1 - 2.8e-16 59.9 15.2 2.8e-16 59.9 15.2 3.4 4 1 0 4 4 4 1 CASC3/Barentsz eIF4AIII binding BUD22 PF09073.10 EKX42544.1 - 1.8 7.8 27.0 0.74 9.1 24.3 1.7 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.12 EKX42544.1 - 6.2 4.9 31.7 9.6 4.3 31.7 1.2 1 0 0 1 1 1 0 Nop14-like family DUF4336 PF14234.6 EKX42545.1 - 4.5e-84 282.4 2.1 3.4e-63 213.8 0.5 2.1 1 1 0 2 2 2 2 Domain of unknown function (DUF4336) DUF4355 PF14265.6 EKX42546.1 - 0.0088 16.3 0.9 0.013 15.7 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4355) SspB PF04386.13 EKX42549.1 - 0.00028 20.8 0.7 0.00032 20.6 0.7 1.1 1 0 0 1 1 1 1 Stringent starvation protein B PMSI1 PF15322.6 EKX42549.1 - 0.0062 16.0 1.7 0.0072 15.8 1.7 1.1 1 0 0 1 1 1 1 Protein missing in infertile sperm 1, putative TFB6 PF17110.5 EKX42549.1 - 0.0065 16.2 0.7 0.0076 16.0 0.7 1.0 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH Connexin PF00029.19 EKX42549.1 - 0.043 13.6 3.0 0.048 13.4 3.0 1.1 1 0 0 1 1 1 0 Connexin RHD_DNA_bind PF00554.22 EKX42549.1 - 0.065 13.2 1.8 0.083 12.8 1.8 1.1 1 0 0 1 1 1 0 Rel homology DNA-binding domain RNA_polI_A34 PF08208.11 EKX42549.1 - 0.11 12.6 16.5 0.12 12.4 16.5 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 FHIPEP PF00771.20 EKX42549.1 - 0.12 10.8 1.1 0.12 10.8 1.1 1.0 1 0 0 1 1 1 0 FHIPEP family EIIBC-GUT_N PF03612.14 EKX42549.1 - 0.17 11.6 4.2 0.18 11.6 4.2 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus FAM176 PF14851.6 EKX42549.1 - 0.22 11.2 6.3 0.29 10.8 6.3 1.1 1 0 0 1 1 1 0 FAM176 family RPN2_C PF18004.1 EKX42549.1 - 0.23 11.4 12.6 0.27 11.1 12.6 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Folate_carrier PF01770.18 EKX42549.1 - 0.3 9.8 0.5 0.27 9.9 0.5 1.0 1 0 0 1 1 1 0 Reduced folate carrier RNA_pol_Rpc4 PF05132.14 EKX42549.1 - 0.33 11.4 5.3 0.39 11.1 5.3 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF3464 PF11947.8 EKX42549.1 - 0.39 10.4 4.3 0.45 10.3 4.3 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Presenilin PF01080.17 EKX42549.1 - 0.41 9.4 2.4 0.42 9.3 2.4 1.0 1 0 0 1 1 1 0 Presenilin Auts2 PF15336.6 EKX42549.1 - 0.43 10.7 4.2 0.49 10.5 4.2 1.1 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein Thg1C PF14413.6 EKX42549.1 - 0.44 10.7 5.5 0.59 10.3 5.5 1.1 1 0 0 1 1 1 0 Thg1 C terminal domain MDM10 PF12519.8 EKX42549.1 - 0.7 8.7 4.1 0.84 8.4 4.1 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Paf1 PF03985.13 EKX42549.1 - 0.91 8.4 14.3 1 8.3 14.3 1.0 1 0 0 1 1 1 0 Paf1 Ferlin_C PF16165.5 EKX42549.1 - 1.6 8.7 13.1 2 8.3 13.1 1.1 1 0 0 1 1 1 0 Ferlin C-terminus CDC45 PF02724.14 EKX42549.1 - 1.6 6.9 8.1 1.9 6.7 8.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S49_N PF08496.10 EKX42549.1 - 4.7 7.3 11.2 6.1 6.9 11.2 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TMEM208_SND2 PF05620.11 EKX42549.1 - 5.2 6.8 4.8 6.1 6.6 4.8 1.2 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 ORC_WH_C PF18137.1 EKX42549.1 - 5.5 7.0 10.6 7.4 6.6 10.6 1.1 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Phage_Gp23 PF10669.9 EKX42549.1 - 8.2 6.8 15.0 11 6.4 15.0 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Rhomboid PF01694.22 EKX42550.1 - 4.6e-21 75.4 11.3 4.6e-21 75.4 11.3 1.6 2 0 0 2 2 2 1 Rhomboid family Neur_chan_memb PF02932.16 EKX42550.1 - 0.18 11.8 0.7 0.27 11.3 0.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Auto_anti-p27 PF06677.12 EKX42552.1 - 5.3e-12 45.7 3.1 1.5e-11 44.3 3.1 1.8 1 1 0 1 1 1 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) FYVE PF01363.21 EKX42553.1 - 3.4e-16 59.1 15.2 2.8e-15 56.2 15.2 1.9 1 1 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 EKX42553.1 - 0.0036 17.5 8.3 0.004 17.4 8.3 1.1 1 0 0 1 1 1 1 FYVE-type zinc finger DZR PF12773.7 EKX42553.1 - 0.07 13.2 11.4 3 8.0 11.4 2.2 1 1 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 EKX42553.1 - 0.17 11.5 8.0 0.53 9.8 4.1 2.4 2 1 0 2 2 2 0 TFIIB zinc-binding zf-RING_5 PF14634.6 EKX42553.1 - 0.39 10.7 13.4 0.53 10.3 13.4 1.2 1 0 0 1 1 1 0 zinc-RING finger domain UbiA PF01040.18 EKX42554.1 - 3.4e-44 151.0 10.2 4.5e-44 150.6 10.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family LrgB PF04172.16 EKX42555.1 - 5.7e-34 117.5 11.3 7.2e-34 117.2 11.3 1.1 1 0 0 1 1 1 1 LrgB-like family Mucin PF01456.17 EKX42556.1 - 0.11 12.4 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein LrgA PF03788.14 EKX42556.1 - 3.9 7.5 7.7 0.18 11.8 1.5 2.1 2 1 0 2 2 2 0 LrgA family YceI PF04264.13 EKX42557.1 - 0.015 15.8 0.0 0.016 15.8 0.0 1.2 1 0 0 1 1 1 0 YceI-like domain TPH PF13868.6 EKX42558.1 - 0.0018 16.9 125.4 0.0027 16.3 125.4 1.2 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain SnoaL_2 PF12680.7 EKX42561.1 - 1.6e-08 35.1 0.0 1.9e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EKX42561.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase PDZ_6 PF17820.1 EKX42563.1 - 1.7e-09 37.4 0.0 3e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX42563.1 - 8.8e-08 32.4 0.0 2.3e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Cep57_CLD_2 PF14197.6 EKX42563.1 - 0.0014 18.6 12.7 0.73 10.0 0.0 3.3 2 1 1 3 3 3 2 Centrosome localisation domain of PPC89 CENP-F_leu_zip PF10473.9 EKX42563.1 - 0.002 18.1 13.6 0.067 13.2 4.4 2.2 1 1 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4201 PF13870.6 EKX42563.1 - 0.0031 17.2 8.4 0.029 14.1 1.5 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4201) Spc7 PF08317.11 EKX42563.1 - 0.012 14.5 11.0 0.027 13.4 11.0 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein bZIP_1 PF00170.21 EKX42563.1 - 0.021 14.9 6.3 0.34 11.0 0.4 2.6 2 0 0 2 2 2 0 bZIP transcription factor TPR_MLP1_2 PF07926.12 EKX42563.1 - 0.028 14.5 1.7 0.028 14.5 1.7 2.4 2 1 1 3 3 2 0 TPR/MLP1/MLP2-like protein HAP1_N PF04849.13 EKX42563.1 - 0.03 13.5 14.3 0.039 13.1 0.5 2.1 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Fez1 PF06818.15 EKX42563.1 - 0.033 14.6 9.2 0.063 13.7 9.2 1.4 1 0 0 1 1 1 0 Fez1 MAD PF05557.13 EKX42563.1 - 0.048 12.0 9.0 0.071 11.5 9.0 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein GAS PF13851.6 EKX42563.1 - 0.059 12.7 12.4 0.22 10.8 6.4 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF812 PF05667.11 EKX42563.1 - 0.085 11.7 10.6 0.12 11.2 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Cluap1 PF10234.9 EKX42563.1 - 0.1 12.0 9.4 0.18 11.2 9.4 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 APG6_N PF17675.1 EKX42563.1 - 0.16 12.5 11.3 0.79 10.3 11.3 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4407 PF14362.6 EKX42563.1 - 0.22 10.8 6.9 0.35 10.2 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 EKX42563.1 - 0.23 11.5 14.1 3.1 7.9 7.5 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 EKX42563.1 - 0.26 12.0 10.1 4.9 7.9 0.3 2.5 1 1 1 2 2 2 0 Initiation control protein YabA Wtap PF17098.5 EKX42563.1 - 0.33 10.9 9.5 0.34 10.8 6.0 2.5 1 1 1 2 2 2 0 WTAP/Mum2p family CALCOCO1 PF07888.11 EKX42563.1 - 0.38 9.6 11.3 0.1 11.4 0.3 2.1 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Flagellin_C PF00700.21 EKX42563.1 - 0.41 11.0 8.3 0.98 9.8 0.6 2.9 2 1 1 3 3 3 0 Bacterial flagellin C-terminal helical region Cob_adeno_trans PF01923.18 EKX42563.1 - 0.44 10.7 4.6 2.6 8.1 0.2 2.2 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DUF724 PF05266.14 EKX42563.1 - 0.46 10.3 6.3 1 9.2 6.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) NRBF2 PF08961.10 EKX42563.1 - 0.54 9.8 6.3 0.97 9.0 6.3 1.4 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator HMMR_N PF15905.5 EKX42563.1 - 0.54 9.7 11.8 0.87 9.0 11.8 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal TMF_DNA_bd PF12329.8 EKX42563.1 - 0.68 10.0 11.7 7.3 6.7 0.6 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding SPATA1_C PF15743.5 EKX42563.1 - 0.82 9.7 11.4 4.2 7.4 9.7 2.3 1 1 0 1 1 1 0 Spermatogenesis-associated C-terminus DivIC PF04977.15 EKX42563.1 - 0.95 9.3 17.6 0.13 12.0 0.8 3.4 2 1 1 3 3 3 0 Septum formation initiator DUF2408 PF10303.9 EKX42563.1 - 1 10.0 9.1 1.6 9.3 5.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Lebercilin PF15619.6 EKX42563.1 - 1 9.0 15.4 0.14 11.8 0.8 2.2 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF2968 PF11180.8 EKX42563.1 - 1.1 8.9 16.3 0.39 10.3 7.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Laminin_II PF06009.12 EKX42563.1 - 1.8 8.6 10.3 2.7 8.0 1.2 2.2 1 1 1 2 2 2 0 Laminin Domain II ATG16 PF08614.11 EKX42563.1 - 2.7 8.2 15.8 4 7.6 5.7 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) USP8_interact PF08941.10 EKX42563.1 - 2.9 7.7 8.5 13 5.6 2.5 2.5 1 1 1 2 2 2 0 USP8 interacting HrpB7 PF09486.10 EKX42563.1 - 4 7.8 10.9 2.4 8.5 7.0 2.4 2 1 0 2 2 1 0 Bacterial type III secretion protein (HrpB7) DUF641 PF04859.12 EKX42563.1 - 4.2 7.7 10.8 23 5.3 4.7 3.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Csm1_N PF18504.1 EKX42563.1 - 4.6 7.7 17.5 0.85 10.0 2.2 3.4 1 1 2 3 3 3 0 Csm1 N-terminal domain UPF0242 PF06785.11 EKX42563.1 - 6.5 6.8 14.0 3.8 7.6 8.6 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Macoilin PF09726.9 EKX42563.1 - 7.2 5.0 7.7 20 3.5 7.7 1.7 1 1 0 1 1 1 0 Macoilin family ABC_tran_CTD PF16326.5 EKX42563.1 - 7.9 6.8 11.3 7.6 6.9 0.3 3.2 2 1 0 2 2 2 0 ABC transporter C-terminal domain cNMP_binding PF00027.29 EKX42564.1 - 0.00022 21.2 0.0 0.00037 20.5 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HSP70 PF00012.20 EKX42565.1 - 4.5e-93 312.5 0.0 5.4e-93 312.2 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EKX42565.1 - 3.4e-11 42.6 0.2 1.1e-10 40.9 0.0 1.7 2 0 0 2 2 2 1 MreB/Mbl protein PilM_2 PF11104.8 EKX42565.1 - 0.0011 18.0 0.1 0.029 13.4 0.0 2.1 2 0 0 2 2 2 1 Type IV pilus assembly protein PilM; DUF1464 PF07318.12 EKX42565.1 - 0.061 12.5 0.0 0.13 11.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1464) Filamin PF00630.19 EKX42566.1 - 2.9e-13 50.5 0.1 3.1e-08 34.4 0.0 3.3 3 0 0 3 3 3 2 Filamin/ABP280 repeat BOP1NT PF08145.12 EKX42567.1 - 7.4e-88 294.8 9.4 7.4e-88 294.8 9.4 1.5 2 0 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.32 EKX42567.1 - 4e-19 68.6 4.6 8.8e-07 29.5 0.1 6.5 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX42567.1 - 1.1e-06 28.8 0.1 3.3e-05 24.1 0.1 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Ephrin_rec_like PF07699.13 EKX42569.1 - 0.019 14.7 1.1 0.041 13.6 1.1 1.6 1 0 0 1 1 1 0 Putative ephrin-receptor like zf-RRN7 PF11781.8 EKX42569.1 - 0.36 10.6 3.0 2.5 7.8 0.9 2.7 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 C2 PF00168.30 EKX42570.1 - 3.9e-09 36.7 0.0 8.2e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain PPTA PF01239.22 EKX42571.1 - 8.4e-16 57.1 7.0 6.1e-05 22.6 0.4 4.5 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat DUF3781 PF12636.7 EKX42571.1 - 0.028 14.3 0.1 0.17 11.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3781) Dynein_AAA_lid PF17852.1 EKX42571.1 - 0.041 14.0 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain Peptidase_A22B PF04258.13 EKX42572.1 - 1.5e-58 198.5 16.0 1.7e-58 198.4 16.0 1.0 1 0 0 1 1 1 1 Signal peptide peptidase LRR_6 PF13516.6 EKX42573.1 - 6.5e-12 44.5 5.6 0.00072 19.4 0.1 5.2 5 1 0 5 5 5 3 Leucine Rich repeat ACT PF01842.25 EKX42573.1 - 0.014 15.1 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 ACT domain LRR_4 PF12799.7 EKX42573.1 - 0.11 13.0 0.4 1.6 9.3 0.3 2.8 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) HABP4_PAI-RBP1 PF04774.15 EKX42574.1 - 0.38 11.6 19.5 0.084 13.7 10.6 2.4 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family p31comet PF06581.12 EKX42575.1 - 3.8e-12 45.9 0.4 1e-11 44.6 0.1 1.7 2 0 0 2 2 2 1 Mad1 and Cdc20-bound-Mad2 binding DEAD PF00270.29 EKX42577.1 - 1.4e-43 148.7 0.0 1.1e-42 145.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX42577.1 - 1.4e-23 83.3 0.0 4.4e-23 81.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX42577.1 - 4.1e-07 30.1 0.0 6e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit MORN PF02493.20 EKX42578.1 - 5.1e-33 111.0 37.0 9.3e-08 31.5 0.5 6.2 6 0 0 6 6 6 6 MORN repeat AP2 PF00847.20 EKX42579.1 - 0.00032 20.9 0.1 0.00073 19.7 0.1 1.7 1 0 0 1 1 1 1 AP2 domain NTP_transf_7 PF07984.12 EKX42580.1 - 0.00014 21.2 0.0 0.00018 20.9 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyltransferase Vac_ImportDeg PF09783.9 EKX42580.1 - 0.03 14.1 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 Vacuolar import and degradation protein Ribosomal_L17 PF01196.19 EKX42581.1 - 3.9e-32 111.0 1.4 5.4e-32 110.6 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L17 Pkinase PF00069.25 EKX42582.1 - 2.7e-30 105.6 0.0 5.1e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX42582.1 - 1.3e-16 60.7 0.0 2.3e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX42582.1 - 6e-05 23.1 0.0 0.038 13.9 0.0 3.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family EF-hand_8 PF13833.6 EKX42582.1 - 0.0001 22.1 0.2 0.00029 20.6 0.2 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 EKX42582.1 - 0.002 18.5 0.2 0.0086 16.5 0.2 2.1 1 0 0 1 1 1 1 EF-hand domain pair TPR_10 PF13374.6 EKX42582.1 - 0.014 15.3 1.3 0.96 9.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Kdo PF06293.14 EKX42582.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Par3_HAL_N_term PF12053.8 EKX42582.1 - 0.027 14.7 0.0 0.075 13.3 0.0 1.7 1 0 0 1 1 1 0 N-terminal of Par3 and HAL proteins EF-hand_1 PF00036.32 EKX42582.1 - 0.081 12.5 0.5 0.28 10.8 0.2 2.2 2 0 0 2 2 2 0 EF hand Pkinase_fungal PF17667.1 EKX42582.1 - 0.13 11.0 6.3 0.28 9.9 6.3 1.8 1 1 0 1 1 1 0 Fungal protein kinase FKBP_C PF00254.28 EKX42583.1 - 1.2e-22 80.1 0.1 7.2e-22 77.5 0.0 2.1 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase SAM_1 PF00536.30 EKX42583.1 - 0.00011 22.5 0.1 0.00026 21.3 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) FlxA PF14282.6 EKX42583.1 - 0.062 13.3 5.2 0.19 11.8 5.2 1.8 1 0 0 1 1 1 0 FlxA-like protein GBR_NSP5 PF17580.2 EKX42583.1 - 0.14 11.9 4.9 0.32 10.8 4.9 1.5 1 0 0 1 1 1 0 Group B Rotavirus Non-structural protein 5 Adaptin_binding PF10199.9 EKX42584.1 - 9.9e-09 35.8 18.0 0.00064 20.3 0.8 2.6 2 1 0 2 2 2 2 Alpha and gamma adaptin binding protein p34 Ras PF00071.22 EKX42584.1 - 7e-06 25.7 0.0 3.2e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 Ras family TPR_11 PF13414.6 EKX42584.1 - 0.0012 18.5 0.4 0.81 9.4 0.0 2.6 2 0 0 2 2 2 2 TPR repeat GTP_EFTU PF00009.27 EKX42584.1 - 0.003 17.1 0.0 0.04 13.4 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain TPR_1 PF00515.28 EKX42584.1 - 0.0031 17.3 5.9 3.7 7.5 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat ABC_tran PF00005.27 EKX42584.1 - 0.0034 17.9 0.7 0.084 13.4 0.0 2.9 3 0 0 3 3 3 1 ABC transporter Roc PF08477.13 EKX42584.1 - 0.0058 16.9 0.0 0.13 12.5 0.0 2.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EKX42584.1 - 0.0078 15.7 0.6 0.11 12.0 0.1 2.6 2 1 0 2 2 2 1 ADP-ribosylation factor family TPR_2 PF07719.17 EKX42584.1 - 0.077 13.2 7.4 16 5.9 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat SLAC1 PF03595.17 EKX42586.1 - 8.8e-16 58.1 30.7 9.9e-16 57.9 30.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel MPC PF03650.13 EKX42586.1 - 0.26 11.4 2.5 0.62 10.2 1.0 2.3 2 1 0 2 2 2 0 Mitochondrial pyruvate carriers Clathrin PF00637.20 EKX42588.1 - 8.4e-170 557.4 30.0 2.2e-26 92.4 0.5 7.9 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 EKX42588.1 - 2.9e-24 84.2 0.4 2.9e-05 24.1 0.0 6.8 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 EKX42588.1 - 8.6e-24 83.2 1.1 2e-22 78.9 0.1 3.5 3 0 0 3 3 3 1 Clathrin-H-link TPR_7 PF13176.6 EKX42588.1 - 5.7e-06 26.0 1.1 41 4.5 0.0 6.6 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 EKX42588.1 - 2.4e-05 24.1 7.4 0.84 9.9 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat Vps39_1 PF10366.9 EKX42588.1 - 2.8e-05 24.3 8.6 0.084 13.2 0.0 5.7 5 0 0 5 5 5 2 Vacuolar sorting protein 39 domain 1 TPR_1 PF00515.28 EKX42588.1 - 0.00014 21.6 5.2 0.42 10.5 0.0 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX42588.1 - 0.00019 22.0 10.5 14 6.8 0.1 8.4 7 1 0 7 7 7 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 EKX42588.1 - 0.0014 17.7 4.6 0.064 12.3 0.2 4.2 4 0 0 4 4 4 1 Coatomer WD associated region Ub-RnfH PF03658.14 EKX42588.1 - 0.0074 16.6 0.0 0.11 12.9 0.0 2.9 3 0 0 3 3 3 1 RnfH family Ubiquitin Retrotran_gag_2 PF14223.6 EKX42588.1 - 0.083 12.6 0.5 6 6.5 0.0 2.9 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type TPR_8 PF13181.6 EKX42588.1 - 0.59 10.5 8.8 89 3.7 0.1 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat BrkDBD PF09607.10 EKX42589.1 - 0.0025 17.5 0.2 0.012 15.4 0.1 2.0 2 0 0 2 2 2 1 Brinker DNA-binding domain Pro_isomerase PF00160.21 EKX42590.1 - 1.8e-49 168.1 0.4 2.1e-49 167.8 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SKA1 PF07160.12 EKX42591.1 - 5.8e-08 32.9 0.5 1.7e-07 31.3 0.0 2.0 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 1 zf-CCCH_8 PF18633.1 EKX42591.1 - 0.37 10.9 0.1 0.37 10.9 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger antiviral protein (ZAP) zinc finger domain 3 FliJ PF02050.16 EKX42592.1 - 0.023 14.9 3.4 0.06 13.6 3.4 1.7 1 0 0 1 1 1 0 Flagellar FliJ protein LPP PF04728.13 EKX42592.1 - 0.023 15.0 1.9 0.075 13.4 1.9 1.8 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Aldo_ket_red PF00248.21 EKX42594.1 - 9.3e-38 130.1 0.5 9.2e-36 123.5 0.5 2.7 1 1 0 1 1 1 1 Aldo/keto reductase family HypF_C PF17788.1 EKX42594.1 - 0.042 14.5 0.0 0.1 13.3 0.0 1.6 1 0 0 1 1 1 0 HypF Kae1-like domain ABC2_membrane PF01061.24 EKX42596.1 - 2.1e-30 105.7 31.2 3.1e-30 105.2 31.2 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EKX42596.1 - 3.2e-24 86.0 0.0 4.7e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EKX42596.1 - 2.7e-08 34.0 0.0 0.0014 18.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EKX42596.1 - 5.3e-05 22.9 0.0 0.00017 21.3 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EKX42596.1 - 0.0001 21.8 0.0 0.00026 20.5 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EKX42596.1 - 0.002 18.7 0.0 0.0032 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EKX42596.1 - 0.0088 16.3 0.1 0.031 14.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EKX42596.1 - 0.0094 15.9 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EKX42596.1 - 0.016 15.6 0.0 0.027 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 EKX42596.1 - 0.017 14.2 0.0 0.031 13.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF677 PF05055.12 EKX42596.1 - 0.019 13.9 0.1 0.039 12.8 0.0 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF677) AAA PF00004.29 EKX42596.1 - 0.057 13.8 0.0 0.31 11.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EKX42596.1 - 0.068 12.7 0.0 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EKX42596.1 - 0.09 12.5 0.0 0.37 10.5 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.6 EKX42596.1 - 0.092 13.3 0.0 0.21 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 EKX42596.1 - 0.21 11.5 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain ABC2_membrane PF01061.24 EKX42597.1 - 1.2e-30 106.5 31.2 1.8e-30 106.0 31.2 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EKX42597.1 - 9.1e-13 48.9 0.0 1.3e-12 48.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EKX42597.1 - 0.00054 19.9 0.0 0.00095 19.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF677 PF05055.12 EKX42597.1 - 0.01 14.7 0.0 0.025 13.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF677) SbcCD_C PF13558.6 EKX42597.1 - 0.14 12.4 0.1 3.8 7.8 0.0 2.8 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 EKX42597.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Glyco_transf_10 PF00852.19 EKX42598.1 - 1.6e-35 122.4 0.7 2.8e-35 121.6 0.7 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Elong_Iki1 PF10483.9 EKX42598.1 - 0.095 12.2 0.1 0.48 9.9 0.0 1.9 1 1 1 2 2 2 0 Elongator subunit Iki1 YMF19 PF02326.15 EKX42598.1 - 0.24 12.2 1.7 0.43 11.4 0.0 2.2 3 0 0 3 3 3 0 Plant ATP synthase F0 YgaB PF14182.6 EKX42600.1 - 0.08 13.3 1.2 0.13 12.7 1.2 1.5 1 1 0 1 1 1 0 YgaB-like protein Aminotran_5 PF00266.19 EKX42601.1 - 7.1e-41 140.4 0.0 8.7e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EKX42601.1 - 1.2e-05 24.7 0.0 2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EKX42601.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EKX42601.1 - 0.035 12.7 0.0 0.053 12.0 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme ABC2_membrane PF01061.24 EKX42602.1 - 6.9e-30 104.0 28.8 9.8e-30 103.5 28.8 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EKX42602.1 - 2e-24 86.7 0.0 3.1e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EKX42602.1 - 8.1e-08 32.4 0.0 0.0033 17.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EKX42602.1 - 8.5e-05 22.2 0.0 0.0003 20.5 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EKX42602.1 - 0.00045 19.7 0.0 0.0013 18.3 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EKX42602.1 - 0.0021 18.6 0.0 0.0035 17.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EKX42602.1 - 0.01 15.0 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 EKX42602.1 - 0.015 15.6 0.0 0.033 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EKX42602.1 - 0.016 15.1 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 EKX42602.1 - 0.021 15.2 0.0 0.034 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 EKX42602.1 - 0.061 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Kinocilin PF15033.6 EKX42602.1 - 0.092 12.4 0.9 0.28 10.8 0.9 1.8 1 0 0 1 1 1 0 Kinocilin protein AAA PF00004.29 EKX42602.1 - 0.11 12.9 0.0 0.37 11.2 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EKX42602.1 - 0.15 11.8 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Rad17 PF03215.15 EKX42602.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 EKX42602.1 - 0.2 12.2 0.0 0.4 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EKX42602.1 - 0.21 11.8 0.2 0.69 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 EKX42602.1 - 0.23 10.2 0.0 0.49 9.1 0.0 1.5 1 0 0 1 1 1 0 Predicted ATPase of the ABC class YgaB PF14182.6 EKX42603.1 - 0.057 13.8 1.2 0.1 13.0 1.3 1.4 1 1 0 1 1 1 0 YgaB-like protein EF-hand_6 PF13405.6 EKX42604.1 - 0.00027 20.6 0.1 0.002 17.9 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EKX42604.1 - 0.0011 18.4 0.0 0.0032 16.9 0.0 1.8 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 EKX42604.1 - 0.002 17.5 0.1 0.0039 16.6 0.1 1.4 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EKX42604.1 - 0.02 15.3 0.0 0.026 15.0 0.0 1.4 1 1 0 1 1 1 0 EF-hand domain pair Vac14_Fig4_bd PF11916.8 EKX42604.1 - 0.13 12.0 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein 14 C-terminal Fig4p binding Retrotrans_gag PF03732.17 EKX42605.1 - 0.0002 21.6 0.9 0.01 16.1 0.0 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein bZIP_1 PF00170.21 EKX42605.1 - 1.9 8.6 7.2 11 6.2 0.2 2.4 2 0 0 2 2 2 0 bZIP transcription factor YgaB PF14182.6 EKX42606.1 - 0.057 13.8 1.2 0.1 13.0 1.3 1.4 1 1 0 1 1 1 0 YgaB-like protein Glyoxalase PF00903.25 EKX42607.1 - 0.00052 20.2 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Stathmin PF00836.19 EKX42607.1 - 0.022 14.7 0.7 0.049 13.6 0.7 1.6 1 0 0 1 1 1 0 Stathmin family GRP PF07172.11 EKX42607.1 - 0.035 14.8 0.1 0.15 12.8 0.1 2.0 1 0 0 1 1 1 0 Glycine rich protein family Tmemb_9 PF05434.11 EKX42607.1 - 0.049 13.5 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 TMEM9 ABC2_membrane PF01061.24 EKX42608.1 - 7e-30 104.0 28.8 1e-29 103.5 28.8 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EKX42608.1 - 1.5e-24 87.0 0.0 2.3e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EKX42608.1 - 1e-07 32.1 0.1 0.0033 17.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EKX42608.1 - 9.1e-05 22.1 0.0 0.0003 20.4 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EKX42608.1 - 0.00067 19.1 0.0 0.0029 17.1 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EKX42608.1 - 0.0025 18.3 0.2 0.0043 17.6 0.2 1.2 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EKX42608.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 EKX42608.1 - 0.014 15.7 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EKX42608.1 - 0.018 15.0 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 EKX42608.1 - 0.028 14.8 0.0 0.044 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 EKX42608.1 - 0.086 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EKX42608.1 - 0.099 13.2 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Kinocilin PF15033.6 EKX42608.1 - 0.1 12.3 0.9 0.29 10.8 0.9 1.7 1 0 0 1 1 1 0 Kinocilin protein IstB_IS21 PF01695.17 EKX42608.1 - 0.15 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA PF00004.29 EKX42608.1 - 0.16 12.4 0.0 0.54 10.7 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EKX42608.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 EKX42608.1 - 0.25 11.6 0.2 0.7 10.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.24 EKX42609.1 - 1.4e-25 89.9 28.8 2.1e-25 89.4 28.8 1.3 1 0 0 1 1 1 1 ABC-2 type transporter Kinocilin PF15033.6 EKX42609.1 - 0.52 10.0 5.8 0.081 12.6 1.3 1.8 2 0 0 2 2 2 0 Kinocilin protein Aminotran_5 PF00266.19 EKX42611.1 - 3.8e-40 138.0 0.0 4.8e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EKX42611.1 - 1e-05 24.9 0.0 1.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EKX42611.1 - 0.01 15.1 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EKX42611.1 - 0.044 12.3 0.0 0.068 11.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PLN_propep PF16485.5 EKX42613.1 - 0.16 11.7 6.9 0.096 12.4 0.3 3.3 3 0 0 3 3 3 0 Protealysin propeptide Fapy_DNA_glyco PF01149.24 EKX42614.1 - 1.3e-27 96.7 0.1 1.1e-16 61.5 0.0 2.3 2 0 0 2 2 2 2 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 EKX42614.1 - 6.7e-20 70.9 0.0 1.1e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 EKX42614.1 - 0.24 10.1 0.0 0.34 9.6 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) TPM_phosphatase PF04536.14 EKX42617.1 - 5e-08 33.2 0.0 6.5e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 TPM domain TAT_signal PF10518.9 EKX42617.1 - 0.029 14.2 0.3 0.06 13.2 0.3 1.6 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence ATG16 PF08614.11 EKX42618.1 - 0.00056 20.2 16.4 0.00056 20.2 16.4 3.7 2 1 1 4 4 4 1 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.12 EKX42618.1 - 0.083 12.9 13.6 1.1 9.3 3.6 3.6 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus RVT_3 PF13456.6 EKX42618.1 - 0.29 11.0 7.5 0.18 11.6 1.0 3.4 3 1 0 3 3 3 0 Reverse transcriptase-like NPV_P10 PF05531.12 EKX42618.1 - 0.58 10.7 11.4 3.1 8.3 1.0 4.6 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DOG1 PF14144.6 EKX42618.1 - 1.6 9.0 0.0 1.6 9.0 0.0 3.0 3 0 0 3 3 3 0 Seed dormancy control Spc7 PF08317.11 EKX42618.1 - 2.6 6.8 46.4 2.1 7.1 12.1 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein PH PF00169.29 EKX42619.1 - 0.00012 22.5 1.0 0.00036 21.0 0.0 2.3 2 1 2 4 4 4 1 PH domain Fur_reg_FbpB PF13040.6 EKX42621.1 - 8.3 6.0 10.8 1.6 8.3 6.7 1.8 2 0 0 2 2 2 0 Fur-regulated basic protein B CLTH PF10607.9 EKX42624.1 - 4.7e-15 55.8 2.7 2.3e-14 53.5 0.1 2.7 1 1 2 3 3 3 1 CTLH/CRA C-terminal to LisH motif domain HalX PF08663.10 EKX42624.1 - 1.3 9.4 6.5 1 9.7 0.2 3.0 3 1 1 4 4 4 0 HalX domain HTH_33 PF13592.6 EKX42625.1 - 0.041 13.5 0.1 0.12 12.0 0.1 1.8 1 0 0 1 1 1 0 Winged helix-turn helix EMP70 PF02990.16 EKX42627.1 - 8.5e-86 288.7 0.0 1.1e-85 288.3 0.0 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 A2M PF00207.22 EKX42627.1 - 0.051 13.4 0.0 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Alpha-2-macroglobulin family ABC2_membrane PF01061.24 EKX42628.1 - 4.3e-35 121.0 28.2 5.9e-35 120.6 28.2 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EKX42628.1 - 5.8e-25 88.4 0.0 8.2e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EKX42628.1 - 1.5e-09 38.1 0.1 0.00012 22.0 0.0 2.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EKX42628.1 - 2.9e-05 23.6 0.0 0.00011 21.7 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EKX42628.1 - 0.00011 21.9 0.5 0.00031 20.4 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EKX42628.1 - 0.0018 18.8 0.0 0.0031 18.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EKX42628.1 - 0.0026 18.0 0.0 0.0093 16.2 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 EKX42628.1 - 0.0041 17.5 0.0 0.0067 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EKX42628.1 - 0.0049 16.8 0.1 0.05 13.5 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase T2SSE PF00437.20 EKX42628.1 - 0.0078 15.3 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.6 EKX42628.1 - 0.028 14.0 0.3 0.1 12.2 0.3 1.9 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EKX42628.1 - 0.035 13.9 0.0 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_ATPase PF09818.9 EKX42628.1 - 0.054 12.3 0.1 0.16 10.7 0.1 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA PF00004.29 EKX42628.1 - 0.14 12.6 0.0 0.77 10.2 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EKX42628.1 - 0.18 12.2 0.0 0.46 10.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 EKX42628.1 - 0.19 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain ABC2_membrane PF01061.24 EKX42629.1 - 8.2e-34 116.9 29.3 1.1e-33 116.4 29.3 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EKX42629.1 - 8.8e-11 42.5 0.0 1.3e-10 41.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EKX42629.1 - 4.5e-05 23.4 0.0 7.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EKX42629.1 - 0.046 13.1 0.0 0.068 12.6 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain T4SS PF07996.11 EKX42630.1 - 0.0038 17.7 10.9 0.0062 17.0 10.9 1.4 1 0 0 1 1 1 1 Type IV secretion system proteins AAA_23 PF13476.6 EKX42630.1 - 0.064 13.8 5.8 0.075 13.5 5.8 1.2 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 EKX42630.1 - 5.5 6.3 11.6 8.5 5.6 11.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EGF_2 PF07974.13 EKX42631.1 - 0.2 12.1 3.4 0.43 11.0 2.1 2.3 2 1 0 2 2 2 0 EGF-like domain Laminin_EGF PF00053.24 EKX42631.1 - 0.33 11.1 5.5 0.81 9.9 5.5 1.6 1 0 0 1 1 1 0 Laminin EGF domain Glyco_transf_11 PF01531.16 EKX42632.1 - 4.9e-22 78.5 0.4 7.5e-22 77.9 0.4 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 11 Aminotran_5 PF00266.19 EKX42634.1 - 8.6e-40 136.8 0.0 1.1e-39 136.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EKX42634.1 - 0.0001 21.6 0.0 0.00015 21.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EKX42634.1 - 0.048 12.2 0.0 0.083 11.4 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DSPc PF00782.20 EKX42635.1 - 2.4e-08 33.8 0.0 2.8e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EKX42635.1 - 2.9e-05 24.2 0.0 3.2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 EKX42635.1 - 0.00014 21.5 0.0 0.00017 21.2 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 EKX42635.1 - 0.012 15.2 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Mo-nitro_C PF06967.11 EKX42635.1 - 0.039 13.9 0.1 0.07 13.1 0.0 1.5 2 0 0 2 2 2 0 Mo-dependent nitrogenase C-terminus Y_phosphatase3 PF13350.6 EKX42635.1 - 0.065 13.2 0.0 0.065 13.2 0.0 1.1 1 0 0 1 1 1 0 Tyrosine phosphatase family IGPS PF00218.21 EKX42636.1 - 3.4e-09 36.3 0.0 6e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase NAD_binding_10 PF13460.6 EKX42636.1 - 0.022 14.7 0.5 0.057 13.3 0.2 1.8 2 0 0 2 2 2 0 NAD(P)H-binding UQ_con PF00179.26 EKX42637.1 - 1.7e-37 128.2 0.1 1.8e-37 128.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EKX42637.1 - 0.0057 16.9 0.0 0.0064 16.8 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 EKX42637.1 - 0.013 15.2 0.0 0.015 15.0 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 EKX42637.1 - 0.023 14.6 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 UEV domain DUF1499 PF07386.11 EKX42639.1 - 7.5e-24 84.5 0.0 9.7e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) PRODH PF18327.1 EKX42639.1 - 0.028 14.6 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 Proline utilization A proline dehydrogenase N-terminal domain DUF2854 PF11016.8 EKX42640.1 - 1.6e-39 135.2 0.0 2.4e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2854) V-ATPase_H_N PF03224.14 EKX42641.1 - 0.0021 17.4 0.3 0.09 12.1 0.1 2.8 2 1 0 2 2 2 1 V-ATPase subunit H Arm PF00514.23 EKX42641.1 - 0.023 14.7 0.0 0.93 9.6 0.0 3.7 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF4509 PF14970.6 EKX42643.1 - 1.3e-08 34.9 0.0 3.1e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4509) PHA-1 PF06542.11 EKX42643.1 - 0.036 12.9 0.5 0.059 12.2 0.5 1.3 1 0 0 1 1 1 0 Regulator protein PHA-1 EGF_2 PF07974.13 EKX42644.1 - 0.0003 21.1 10.3 0.0003 21.1 10.3 2.6 2 1 0 2 2 2 1 EGF-like domain EGF_Tenascin PF18720.1 EKX42644.1 - 0.017 15.1 0.2 0.017 15.1 0.2 2.5 3 0 0 3 3 3 0 Tenascin EGF domain EGF PF00008.27 EKX42644.1 - 0.47 10.8 13.7 0.18 12.2 10.0 2.3 2 0 0 2 2 2 0 EGF-like domain RXT2_N PF08595.11 EKX42644.1 - 2 8.4 6.3 0.27 11.2 1.8 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal RRN3 PF05327.11 EKX42644.1 - 2.6 6.5 4.3 3.5 6.1 4.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CENP-B_dimeris PF09026.10 EKX42644.1 - 5.1 7.5 26.2 0.087 13.2 13.3 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 EKX42644.1 - 5.1 6.7 17.4 0.027 14.2 7.9 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein hEGF PF12661.7 EKX42644.1 - 9 7.1 13.0 1.5 9.6 6.9 2.8 2 0 0 2 2 2 0 Human growth factor-like EGF Nop14 PF04147.12 EKX42645.1 - 0.00088 17.6 41.9 0.001 17.4 41.9 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 EKX42645.1 - 0.0049 16.4 43.6 0.0054 16.2 43.6 1.0 1 0 0 1 1 1 1 SDA1 Mpp10 PF04006.12 EKX42645.1 - 0.093 11.2 40.7 0.11 10.9 40.7 1.0 1 0 0 1 1 1 0 Mpp10 protein SpoIIIAH PF12685.7 EKX42645.1 - 0.23 11.3 17.2 0.33 10.8 17.2 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein RR_TM4-6 PF06459.12 EKX42645.1 - 0.46 10.3 10.6 0.59 9.9 10.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.8 EKX42645.1 - 0.59 8.9 9.5 0.75 8.5 9.5 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Paf1 PF03985.13 EKX42645.1 - 0.9 8.5 26.0 1.1 8.1 26.0 1.3 1 0 0 1 1 1 0 Paf1 Connexin PF00029.19 EKX42645.1 - 1.3 8.8 3.3 1.8 8.2 3.3 1.4 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 EKX42645.1 - 3.3 6.4 10.3 3.5 6.3 10.3 1.1 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 EKX42645.1 - 3.5 5.4 9.6 3.7 5.3 9.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PNISR PF15996.5 EKX42645.1 - 3.7 7.8 20.8 4.5 7.5 20.8 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR SLC12 PF03522.15 EKX42645.1 - 4.1 6.3 7.9 4.6 6.1 7.9 1.0 1 0 0 1 1 1 0 Solute carrier family 12 RNA_pol_Rpc4 PF05132.14 EKX42645.1 - 6.7 7.1 12.3 12 6.3 12.3 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Merozoite_SPAM PF07133.11 EKX42645.1 - 7.6 6.5 53.5 11 6.0 53.5 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) eIF-3c_N PF05470.12 EKX42645.1 - 8 4.6 22.0 11 4.2 22.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CENP-F_leu_zip PF10473.9 EKX42646.1 - 0.005 16.9 14.1 0.005 16.9 14.1 14.5 7 3 5 13 13 13 7 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RWP-RK PF02042.15 EKX42649.1 - 1.2e-12 47.6 0.0 2.1e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain DUF4618 PF15397.6 EKX42649.1 - 0.031 13.7 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Castor1_N PF18700.1 EKX42649.1 - 0.23 11.3 0.6 0.39 10.6 0.0 1.6 2 0 0 2 2 2 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain RWP-RK PF02042.15 EKX42650.1 - 2.2e-15 56.4 0.1 4e-15 55.5 0.1 1.5 1 0 0 1 1 1 1 RWP-RK domain Sigma70_r4_2 PF08281.12 EKX42650.1 - 0.0075 15.9 0.0 0.018 14.7 0.0 1.6 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_8 PF02954.19 EKX42650.1 - 0.038 13.8 0.2 0.84 9.5 0.0 2.2 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family HTH_24 PF13412.6 EKX42650.1 - 0.071 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding CENP-B_dimeris PF09026.10 EKX42650.1 - 2.6 8.5 6.1 1.5 9.3 4.1 1.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RWP-RK PF02042.15 EKX42651.1 - 9.2e-16 57.6 0.1 1.3e-15 57.0 0.1 1.2 1 0 0 1 1 1 1 RWP-RK domain Sigma70_r4_2 PF08281.12 EKX42651.1 - 0.019 14.7 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_8 PF02954.19 EKX42651.1 - 0.03 14.1 0.4 0.76 9.6 0.0 2.4 2 1 1 3 3 3 0 Bacterial regulatory protein, Fis family HTH_24 PF13412.6 EKX42651.1 - 0.16 11.5 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding RPN2_C PF18004.1 EKX42652.1 - 0.018 15.0 4.9 0.13 12.2 0.2 2.4 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain PTPRCAP PF15713.5 EKX42652.1 - 9.8 6.5 18.1 0.85 9.9 2.2 2.9 3 0 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated CHB_HEX_C_1 PF13290.6 EKX42653.1 - 0.22 11.5 0.0 0.4 10.7 0.0 1.4 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain DUF826 PF05696.11 EKX42654.1 - 0.12 12.5 1.3 0.3 11.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF826) Methyltransf_25 PF13649.6 EKX42656.1 - 5.7e-11 43.0 0.0 8.3e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX42656.1 - 7.6e-09 36.1 0.0 1.1e-08 35.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX42656.1 - 5.7e-08 32.7 0.0 6.2e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX42656.1 - 1.6e-06 28.7 0.0 2.4e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EKX42656.1 - 5.7e-05 22.7 0.0 8.9e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EKX42656.1 - 0.00035 20.0 0.0 0.00046 19.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 EKX42656.1 - 0.00064 19.6 0.0 0.00078 19.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EKX42656.1 - 0.0014 18.6 0.1 0.0022 18.0 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX42656.1 - 0.0019 17.6 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_33 PF10017.9 EKX42656.1 - 0.014 14.5 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent TehB PF03848.14 EKX42656.1 - 0.015 14.8 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB UPF0146 PF03686.13 EKX42656.1 - 0.017 15.0 0.1 0.033 14.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) FF PF01846.19 EKX42656.1 - 0.037 14.2 0.3 0.82 9.9 0.0 2.7 3 0 0 3 3 3 0 FF domain DUF3236 PF11576.8 EKX42656.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) FtsJ PF01728.19 EKX42656.1 - 0.12 12.4 0.1 0.24 11.5 0.1 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase MetW PF07021.12 EKX42656.1 - 0.13 11.9 0.3 0.18 11.3 0.3 1.4 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW 2OG-FeII_Oxy_3 PF13640.6 EKX42657.1 - 1.9e-05 25.5 0.3 0.0029 18.5 0.0 2.3 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 EKX42657.1 - 0.0012 19.2 0.0 0.0017 18.7 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_4 PF13661.6 EKX42657.1 - 0.014 16.0 0.5 0.96 10.2 0.1 2.2 1 1 1 2 2 2 0 2OG-Fe(II) oxygenase superfamily DUF3224 PF11528.8 EKX42657.1 - 0.19 11.5 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3224) Kelch_1 PF01344.25 EKX42658.1 - 4e-73 240.8 8.4 2.1e-16 59.2 0.0 6.0 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 EKX42658.1 - 1.2e-41 139.7 5.3 4.5e-10 39.5 0.0 6.0 1 1 5 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EKX42658.1 - 3.2e-30 102.9 1.6 3e-06 27.0 0.0 5.9 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 EKX42658.1 - 2.9e-21 75.2 5.5 4.2e-05 23.5 0.0 5.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EKX42658.1 - 6.8e-21 74.1 5.4 2.2e-06 27.8 0.0 5.3 4 1 1 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EKX42658.1 - 4.7e-14 52.0 8.1 0.0059 16.6 0.0 5.8 6 0 0 6 6 6 4 Kelch motif PQQ_3 PF13570.6 EKX42658.1 - 4e-06 27.2 2.2 4.2 8.0 0.0 5.4 6 0 0 6 6 6 1 PQQ-like domain SYS1 PF09801.9 EKX42660.1 - 3.3e-08 33.8 12.0 9.4e-08 32.3 12.0 1.6 1 1 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network COX4_pro PF03626.14 EKX42660.1 - 0.25 11.8 8.2 0.1 13.0 4.0 2.0 2 0 0 2 2 2 0 Prokaryotic Cytochrome C oxidase subunit IV LapA_dom PF06305.11 EKX42660.1 - 1.3 8.8 7.2 0.092 12.6 1.1 2.1 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain RWP-RK PF02042.15 EKX42661.1 - 3.8e-15 55.6 0.0 5.2e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 RWP-RK domain TetR_N PF00440.23 EKX42661.1 - 0.13 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family RWP-RK PF02042.15 EKX42662.1 - 6.5e-15 54.8 0.0 9.8e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain Phage-tail_3 PF13550.6 EKX42662.1 - 0.072 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative phage tail protein Pkinase PF00069.25 EKX42663.1 - 7.6e-18 64.8 0.0 1.1e-17 64.3 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX42663.1 - 0.032 13.5 0.7 0.076 12.3 0.0 1.9 3 0 0 3 3 3 0 Protein tyrosine kinase DnaJ PF00226.31 EKX42665.1 - 5.7e-19 68.0 2.2 1.8e-18 66.4 0.9 2.1 2 0 0 2 2 2 1 DnaJ domain Asp PF00026.23 EKX42666.1 - 0.00016 21.2 0.0 0.08 12.4 0.1 2.7 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 EKX42666.1 - 0.00062 19.6 0.0 0.0025 17.6 0.0 2.0 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 EKX42666.1 - 0.098 13.3 0.2 14 6.5 0.1 2.6 2 0 0 2 2 2 0 Aspartyl protease AAA PF00004.29 EKX42667.1 - 7.3e-40 136.5 0.0 1.2e-39 135.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EKX42667.1 - 1.3e-16 60.1 0.0 6.4e-16 57.9 0.0 2.4 1 1 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 EKX42667.1 - 7e-10 38.8 0.0 1.6e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 EKX42667.1 - 1.7e-05 24.6 0.0 3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EKX42667.1 - 0.00025 21.2 0.0 0.00053 20.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EKX42667.1 - 0.00036 20.7 0.0 0.0014 18.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EKX42667.1 - 0.00094 19.5 0.2 0.099 12.9 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 EKX42667.1 - 0.0014 18.6 0.1 0.012 15.6 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EKX42667.1 - 0.0021 18.1 0.0 0.0059 16.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.13 EKX42667.1 - 0.0024 17.1 0.0 0.0041 16.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain ATPase PF06745.13 EKX42667.1 - 0.0025 17.2 0.0 0.78 9.0 0.0 2.5 1 1 1 2 2 2 1 KaiC Mg_chelatase PF01078.21 EKX42667.1 - 0.0042 16.5 0.0 0.0082 15.5 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EKX42667.1 - 0.0051 16.4 0.1 0.011 15.3 0.1 1.5 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 EKX42667.1 - 0.0054 16.5 0.1 0.016 15.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EKX42667.1 - 0.01 16.3 0.1 0.022 15.2 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 EKX42667.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 EKX42667.1 - 0.026 14.9 0.0 0.078 13.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 EKX42667.1 - 0.031 14.3 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 EKX42667.1 - 0.034 13.6 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 EKX42667.1 - 0.042 13.6 0.0 0.84 9.3 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.11 EKX42667.1 - 0.048 13.5 0.0 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 EKX42667.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 EKX42667.1 - 0.12 12.6 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EKX42667.1 - 0.14 11.7 0.2 0.75 9.3 0.1 2.0 1 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EKX42667.1 - 0.16 12.5 0.0 0.37 11.3 0.0 1.6 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.6 EKX42667.1 - 0.6 10.7 2.4 0.62 10.6 0.1 2.3 3 1 0 3 3 3 0 AAA domain FKBP_C PF00254.28 EKX42668.1 - 2.2e-27 95.2 0.0 4.7e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 EKX42668.1 - 1.8e-11 43.4 0.0 0.0042 16.8 0.0 3.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX42668.1 - 5.9e-08 32.3 0.0 0.0009 19.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX42668.1 - 1e-07 31.6 0.1 0.0058 16.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX42668.1 - 1.1e-05 24.9 0.0 0.46 10.2 0.0 3.2 3 0 0 3 3 3 2 TPR repeat TPR_9 PF13371.6 EKX42668.1 - 2.4e-05 24.4 0.0 3.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX42668.1 - 0.0003 21.0 0.2 0.61 10.6 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX42668.1 - 0.00034 21.1 0.0 0.00098 19.6 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX42668.1 - 0.0047 17.0 0.0 0.23 11.5 0.0 2.4 1 1 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 EKX42668.1 - 0.04 14.7 0.0 3.2 8.8 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX42668.1 - 0.14 12.9 0.0 1.2 9.9 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Atx10homo_assoc PF09759.9 EKX42670.1 - 1.2e-07 31.6 0.0 3.6e-05 23.7 0.0 2.3 1 1 1 2 2 2 2 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 EKX42670.1 - 0.002 18.1 1.0 7.7 6.7 0.0 4.2 4 1 0 4 4 4 2 Armadillo/beta-catenin-like repeat Pkinase PF00069.25 EKX42671.1 - 1e-37 129.9 0.0 1.1e-37 129.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX42671.1 - 2.8e-33 115.3 0.0 3.3e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX42671.1 - 4.5e-05 22.4 0.0 8.4e-05 21.5 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EKX42671.1 - 5.5e-05 22.6 0.0 9.2e-05 21.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EKX42671.1 - 8.2e-05 22.6 0.0 0.0002 21.4 0.0 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX42671.1 - 0.006 15.9 0.0 0.009 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EKX42671.1 - 0.035 13.2 0.0 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 EKX42671.1 - 0.076 12.6 0.0 0.18 11.4 0.0 1.6 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EKX42671.1 - 0.094 12.3 0.1 0.22 11.1 0.1 1.7 1 1 0 1 1 1 0 RIO1 family Epimerase PF01370.21 EKX42672.1 - 1.3e-14 54.3 0.0 9.4e-10 38.4 0.0 2.3 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EKX42672.1 - 6.3e-12 45.8 0.0 1.1e-11 45.0 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EKX42672.1 - 3.5e-09 36.5 0.0 8.7e-05 22.1 0.0 2.1 1 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EKX42672.1 - 5.7e-09 35.9 0.0 7.9e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 EKX42672.1 - 1.1e-05 24.7 0.0 0.0012 18.0 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain adh_short PF00106.25 EKX42672.1 - 0.057 12.9 0.1 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase NAD_binding_2 PF03446.15 EKX42672.1 - 0.12 12.6 0.0 0.31 11.2 0.0 1.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Acetyltransf_1 PF00583.25 EKX42673.1 - 7.9e-12 45.5 0.0 1.1e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EKX42673.1 - 1.1e-10 41.8 0.0 2.1e-10 40.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EKX42673.1 - 3.6e-08 33.4 0.0 1.4e-07 31.5 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 EKX42673.1 - 0.0004 20.1 0.1 0.00048 19.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ FR47 PF08445.10 EKX42673.1 - 0.0013 18.7 0.0 0.0078 16.2 0.0 2.1 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EKX42673.1 - 0.014 15.5 0.0 0.065 13.3 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EKX42673.1 - 0.05 13.7 0.0 0.088 13.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase RWP-RK PF02042.15 EKX42674.1 - 1e-15 57.4 0.4 1.6e-15 56.8 0.4 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX42674.1 - 0.014 15.1 0.3 0.1 12.4 0.0 2.3 2 1 1 3 3 3 0 Bacterial regulatory protein, Fis family Sigma70_r4_2 PF08281.12 EKX42674.1 - 0.049 13.3 0.1 0.09 12.5 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 YL1 PF05764.13 EKX42674.1 - 0.12 12.5 2.5 0.17 11.9 2.5 1.3 1 1 0 1 1 1 0 YL1 nuclear protein PFK PF00365.20 EKX42675.1 - 1.1e-40 139.7 0.0 2.8e-40 138.5 0.0 1.6 1 1 0 1 1 1 1 Phosphofructokinase Peptidase_M30 PF10460.9 EKX42675.1 - 0.22 10.4 0.0 0.29 10.0 0.0 1.1 1 0 0 1 1 1 0 Peptidase M30 Acetyltransf_1 PF00583.25 EKX42676.1 - 4.5e-19 68.8 0.0 6.2e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EKX42676.1 - 3e-14 53.2 0.0 4.8e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EKX42676.1 - 3.7e-14 52.7 0.0 7.5e-14 51.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EKX42676.1 - 9.6e-08 31.9 0.0 1.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EKX42676.1 - 0.0012 19.5 0.0 0.0019 18.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EKX42676.1 - 0.0021 18.1 0.1 0.011 15.8 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EKX42676.1 - 0.0034 17.5 0.0 0.0054 16.8 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 EKX42676.1 - 0.04 14.0 0.0 0.08 13.1 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain LRR_6 PF13516.6 EKX42677.1 - 0.021 14.8 2.4 0.032 14.3 0.2 2.5 2 0 0 2 2 2 0 Leucine Rich repeat RYDR_ITPR PF01365.21 EKX42677.1 - 0.025 14.0 0.6 1.7 8.1 0.0 3.1 3 0 0 3 3 3 0 RIH domain DUF682 PF05081.12 EKX42677.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF682) LRR_4 PF12799.7 EKX42677.1 - 4.3 7.9 8.3 1.1 9.7 3.9 2.3 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) ANAPC4_WD40 PF12894.7 EKX42679.1 - 1.8e-08 34.5 1.7 0.12 12.7 0.0 5.3 4 2 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 EKX42679.1 - 0.00018 20.9 0.1 0.0053 16.1 0.0 2.9 1 1 1 2 2 2 1 Neuroblastoma-amplified sequence, N terminal WD40 PF00400.32 EKX42679.1 - 0.0002 22.1 11.5 7 7.7 0.1 7.6 6 1 0 6 6 6 2 WD domain, G-beta repeat Nucleoporin_N PF08801.11 EKX42679.1 - 0.0042 15.9 0.1 0.44 9.2 0.1 2.4 2 0 0 2 2 2 2 Nup133 N terminal like HPS3_N PF14761.6 EKX42679.1 - 0.011 15.3 0.2 0.83 9.1 0.1 2.5 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 DUF4338 PF14236.6 EKX42679.1 - 0.037 13.3 0.0 0.094 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4338) Sporozoite_P67 PF05642.11 EKX42679.1 - 0.36 8.9 5.7 0.69 7.9 5.7 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TPR_10 PF13374.6 EKX42680.1 - 0.00052 19.8 0.0 0.0016 18.2 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat DivIC PF04977.15 EKX42680.1 - 0.015 15.0 4.8 0.015 15.0 4.8 5.9 5 3 2 7 7 7 0 Septum formation initiator TPR_12 PF13424.6 EKX42680.1 - 0.055 13.8 0.0 0.92 9.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Thiamine_BP PF01910.17 EKX42680.1 - 0.11 12.4 0.0 0.38 10.7 0.0 1.8 1 0 0 1 1 1 0 Thiamine-binding protein RTX_C PF08339.10 EKX42680.1 - 0.69 10.0 6.3 0.22 11.6 2.7 2.1 2 1 0 2 2 2 0 RTX C-terminal domain Shugoshin_N PF07558.11 EKX42680.1 - 1.1 9.2 9.0 0.13 12.1 2.2 2.7 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Methyltransf_11 PF08241.12 EKX42681.1 - 0.17 12.6 0.0 1.4 9.6 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain WD40 PF00400.32 EKX42682.1 - 1.6e-68 224.9 21.0 1.4e-08 35.2 0.0 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX42682.1 - 4e-19 68.7 2.6 0.004 17.4 0.0 7.5 2 1 7 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EKX42682.1 - 1.6e-09 37.6 3.2 0.0016 17.8 0.1 5.1 3 2 1 5 5 5 2 WD40-like domain WD40_3 PF15911.5 EKX42682.1 - 1.2e-06 28.5 0.0 0.039 14.0 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EKX42682.1 - 2.8e-05 23.2 10.7 0.41 9.6 1.0 5.1 1 1 5 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EKX42682.1 - 0.0001 21.1 9.6 3.7 6.1 0.0 6.3 2 2 5 7 7 7 3 Nucleoporin Nup120/160 CEP19 PF14933.6 EKX42682.1 - 0.00024 21.5 0.2 0.00034 21.0 0.2 1.2 1 0 0 1 1 1 1 CEP19-like protein Frtz PF11768.8 EKX42682.1 - 0.0018 16.7 0.1 0.7 8.1 0.0 4.1 3 1 2 5 5 5 1 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 EKX42682.1 - 0.014 14.3 0.5 1.6 7.6 0.0 3.2 3 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain KAP PF05804.12 EKX42682.1 - 0.019 13.2 0.1 0.026 12.7 0.1 1.1 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) ATP_bind_3 PF01171.20 EKX42683.1 - 1.2e-43 149.0 0.1 1.7e-43 148.5 0.1 1.2 1 0 0 1 1 1 1 PP-loop family TilS_C PF11734.8 EKX42683.1 - 7.6e-06 25.3 0.1 1.9e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 TilS substrate C-terminal domain PAPS_reduct PF01507.19 EKX42683.1 - 0.0047 17.0 0.0 0.01 15.9 0.0 1.6 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family SR-25 PF10500.9 EKX42683.1 - 2.5 7.7 14.4 4.3 6.9 14.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 EKX42683.1 - 3.6 8.3 11.2 8.4 7.1 11.2 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF755 PF05501.11 EKX42683.1 - 6.9 7.0 13.1 1.3 9.4 8.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF755) PDZ_6 PF17820.1 EKX42685.1 - 0.00017 21.3 0.2 0.00038 20.2 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX42685.1 - 0.00025 21.3 0.1 0.00066 20.0 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX42685.1 - 0.0049 17.2 0.1 0.013 15.9 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PSII_Pbs27 PF13326.6 EKX42685.1 - 0.048 14.0 0.2 0.089 13.1 0.2 1.4 1 0 0 1 1 1 0 Photosystem II Pbs27 COMMD1_N PF17221.3 EKX42685.1 - 0.067 13.5 3.0 0.12 12.7 0.0 2.7 2 1 1 3 3 3 0 COMMD1 N-terminal domain DUF1043 PF06295.12 EKX42685.1 - 0.7 9.9 11.1 5 7.2 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) Syntaxin-6_N PF09177.11 EKX42685.1 - 5.3 7.7 15.2 0.39 11.3 0.5 3.3 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Actin PF00022.19 EKX42686.1 - 5.4e-137 456.7 0.0 1.6e-136 455.2 0.0 1.6 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EKX42686.1 - 0.081 11.7 0.0 1.4 7.7 0.0 2.3 2 1 0 2 2 2 0 MreB/Mbl protein PAS_8 PF13188.7 EKX42687.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 PAS domain TruD PF01142.18 EKX42688.1 - 2.9e-24 85.7 0.0 3.3e-24 85.5 0.0 1.0 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) DUF2313 PF10076.9 EKX42688.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2313) LRR_8 PF13855.6 EKX42689.1 - 1.5e-28 98.3 19.7 5.4e-18 64.5 3.7 3.1 1 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EKX42689.1 - 1.2e-16 60.6 32.8 1.4e-06 28.6 4.1 3.7 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX42689.1 - 1.3e-10 41.3 0.8 2.1e-10 40.7 0.8 1.3 1 0 0 1 1 1 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 EKX42689.1 - 8.3e-07 28.7 1.5 0.00021 20.9 0.0 2.6 1 1 2 3 3 3 1 Leucine-rich repeat LRR_1 PF00560.33 EKX42689.1 - 2e-06 27.5 14.3 0.04 14.5 0.3 6.5 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.6 EKX42689.1 - 0.0089 16.0 13.9 2.6 8.3 0.1 4.7 5 0 0 5 5 5 3 Leucine Rich repeat Pheromone PF08015.11 EKX42689.1 - 0.87 10.7 6.7 0.44 11.6 1.1 2.5 2 0 0 2 2 2 0 Fungal mating-type pheromone LRR_8 PF13855.6 EKX42690.1 - 2.6e-103 337.8 118.5 2e-16 59.5 10.0 10.0 1 1 9 10 10 10 10 Leucine rich repeat LRR_5 PF13306.6 EKX42690.1 - 6.3e-54 181.4 10.5 1.3e-15 57.5 0.2 4.7 1 1 4 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 EKX42690.1 - 1.1e-52 175.0 134.8 1.6e-07 31.5 4.4 10.7 1 1 12 15 15 15 15 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX42690.1 - 3.8e-25 84.5 75.5 0.046 14.3 0.7 16.7 17 0 0 17 17 17 12 Leucine Rich Repeat LRR_9 PF14580.6 EKX42690.1 - 2.6e-20 72.6 16.4 3.6e-05 23.3 0.0 6.0 1 1 3 5 5 5 5 Leucine-rich repeat LRR_6 PF13516.6 EKX42690.1 - 4.3e-11 42.0 57.8 0.15 12.1 0.2 14.9 15 0 0 15 15 15 7 Leucine Rich repeat LRR_2 PF07723.13 EKX42690.1 - 0.16 12.7 10.1 25 5.8 0.0 7.4 9 0 0 9 9 9 0 Leucine Rich Repeat SAM_3 PF18016.1 EKX42690.1 - 5.8 6.8 11.2 10 6.0 0.1 4.9 4 1 1 5 5 5 0 SAM domain (Sterile alpha motif) SopA PF13981.6 EKX42691.1 - 0.12 12.8 1.1 0.24 11.8 1.1 1.6 1 1 0 1 1 1 0 SopA-like central domain Dsh_C PF12316.8 EKX42692.1 - 4.1 7.8 11.6 8 6.8 11.6 1.5 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal PcfJ PF14284.6 EKX42692.1 - 4.9 7.0 16.9 1.1 9.2 1.2 2.9 2 1 0 2 2 2 0 PcfJ-like protein WWE PF02825.20 EKX42693.1 - 8.4e-08 32.7 0.1 0.018 15.6 0.0 2.6 2 1 0 2 2 2 2 WWE domain HEAT PF02985.22 EKX42694.1 - 2.7e-05 24.1 0.1 4.6 7.8 0.0 4.2 4 0 0 4 4 4 3 HEAT repeat Arm PF00514.23 EKX42694.1 - 9.5e-05 22.3 2.0 0.53 10.4 0.1 4.6 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EKX42694.1 - 0.018 15.4 5.1 6.2 7.3 0.1 4.5 3 2 1 4 4 4 0 HEAT repeats DUF1593 PF07632.11 EKX42694.1 - 0.044 13.2 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) HEAT_EZ PF13513.6 EKX42694.1 - 2.2 8.9 5.9 27 5.4 0.1 3.0 3 0 0 3 3 3 0 HEAT-like repeat cNMP_binding PF00027.29 EKX42695.1 - 2.4e-15 56.3 0.0 8.4e-15 54.6 0.0 1.9 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain SPRY PF00622.28 EKX42696.1 - 0.18 11.9 0.1 1.5 9.0 0.0 2.4 2 1 0 2 2 2 0 SPRY domain TPR_2 PF07719.17 EKX42696.1 - 0.43 10.8 2.2 26 5.3 0.7 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat YfhO PF09586.10 EKX42697.1 - 0.23 9.7 3.9 0.28 9.4 3.9 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF2339 PF10101.9 EKX42697.1 - 1.1 7.8 9.2 0.051 12.2 3.6 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2339) Smr PF01713.21 EKX42698.1 - 9.3e-06 25.9 0.1 3e-05 24.3 0.1 1.9 1 0 0 1 1 1 1 Smr domain RAB3GAP2_C PF14656.6 EKX42698.1 - 0.065 11.5 0.1 0.16 10.1 0.1 1.5 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit C-terminus MxiM PF11441.8 EKX42698.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.6 2 0 0 2 2 2 0 Pilot protein MxiM O-FucT PF10250.9 EKX42699.1 - 0.00045 20.0 0.0 0.00066 19.5 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase RWP-RK PF02042.15 EKX42700.1 - 5.2e-12 45.6 0.0 1.3e-11 44.3 0.0 1.6 1 1 0 1 1 1 1 RWP-RK domain HTH_37 PF13744.6 EKX42700.1 - 0.032 14.2 0.1 0.083 12.9 0.1 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain Xan_ur_permease PF00860.20 EKX42700.1 - 0.16 10.6 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Permease family RWP-RK PF02042.15 EKX42701.1 - 1.9e-09 37.4 0.1 3e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX42701.1 - 0.048 13.5 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family RWP-RK PF02042.15 EKX42702.1 - 5e-12 45.6 0.1 1.3e-11 44.3 0.1 1.6 1 1 0 1 1 1 1 RWP-RK domain HTH_37 PF13744.6 EKX42702.1 - 0.051 13.5 0.1 0.077 13.0 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain MORN PF02493.20 EKX42703.1 - 2.1e-23 80.7 19.4 3.1e-05 23.6 0.3 6.0 6 0 0 6 6 6 5 MORN repeat Stc1 PF12898.7 EKX42703.1 - 5.6 7.6 8.9 0.89 10.1 4.0 2.0 2 0 0 2 2 2 0 Stc1 domain rRNA_proc-arch PF13234.6 EKX42704.1 - 1.3e-68 231.8 0.9 1.3e-68 231.8 0.9 2.9 3 0 0 3 3 3 1 rRNA-processing arch domain DSHCT PF08148.12 EKX42704.1 - 1.1e-50 171.5 0.6 2.3e-50 170.5 0.6 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 EKX42704.1 - 4.2e-16 59.2 0.0 1.6e-15 57.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX42704.1 - 4.4e-07 30.2 0.0 7.4e-06 26.3 0.0 2.6 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Receptor_IA-2 PF11548.8 EKX42704.1 - 0.12 12.3 0.1 0.41 10.6 0.1 1.9 1 0 0 1 1 1 0 Protein-tyrosine phosphatase receptor IA-2 APG6_N PF17675.1 EKX42704.1 - 0.34 11.5 0.1 0.34 11.5 0.1 3.6 4 0 0 4 4 4 0 Apg6 coiled-coil region Lectin_C PF00059.21 EKX42705.1 - 1.7e-12 48.0 0.4 4.9e-12 46.5 0.4 1.8 1 0 0 1 1 1 1 Lectin C-type domain CUB PF00431.20 EKX42705.1 - 0.12 12.8 0.0 0.41 11.0 0.0 2.0 1 0 0 1 1 1 0 CUB domain PDZ PF00595.24 EKX42706.1 - 1.4e-05 25.3 1.2 2.9e-05 24.3 0.2 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EKX42706.1 - 0.00093 19.0 0.1 0.0025 17.6 0.1 1.7 1 0 0 1 1 1 1 PDZ domain Med15 PF09606.10 EKX42706.1 - 0.081 11.6 23.3 0.12 11.1 23.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CDC27 PF09507.10 EKX42706.1 - 4.7 6.5 50.6 0.18 11.2 44.2 1.7 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 BCAS2 PF05700.11 EKX42707.1 - 1.5e-43 148.9 10.7 4.6e-42 144.0 10.7 2.0 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) ANAPC5 PF12862.7 EKX42707.1 - 0.078 13.0 0.9 1.1 9.3 0.1 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 Leuk-A4-hydro_C PF09127.11 EKX42707.1 - 0.12 12.5 0.2 0.99 9.5 0.1 2.3 2 0 0 2 2 2 0 Leukotriene A4 hydrolase, C-terminal DUF2076 PF09849.9 EKX42709.1 - 0.00069 19.7 5.8 0.00089 19.4 5.8 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) UVR PF02151.19 EKX42710.1 - 3.5e-09 36.1 3.7 6.7e-06 25.7 0.7 2.3 2 0 0 2 2 2 2 UvrB/uvrC motif PD40 PF07676.12 EKX42710.1 - 0.025 14.5 0.0 2.7 8.0 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat cNMP_binding PF00027.29 EKX42712.1 - 2.4e-11 43.6 0.0 6.9e-11 42.1 0.0 1.7 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain Glyco_transf_41 PF13844.6 EKX42713.1 - 7.5e-30 103.8 0.1 1.2e-28 99.9 0.0 2.0 2 0 0 2 2 2 2 Glycosyl transferase family 41 OHCU_decarbox PF09349.10 EKX42714.1 - 0.1 13.1 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 OHCU decarboxylase Fcf2 PF08698.11 EKX42715.1 - 5.6e-20 71.5 0.9 5.6e-20 71.5 0.9 1.6 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing PLA2_B PF01735.18 EKX42715.1 - 0.12 10.8 0.0 0.13 10.6 0.0 1.0 1 0 0 1 1 1 0 Lysophospholipase catalytic domain Cornichon PF03311.14 EKX42717.1 - 2.2e-17 63.5 1.9 2.9e-17 63.1 1.9 1.1 1 0 0 1 1 1 1 Cornichon protein SNARE_assoc PF09335.11 EKX42717.1 - 0.024 15.1 0.2 0.076 13.5 0.0 1.8 1 1 1 2 2 2 0 SNARE associated Golgi protein Sel1 PF08238.12 EKX42718.1 - 2.7e-54 180.4 41.6 5.7e-07 30.0 0.0 16.5 15 2 0 15 15 15 12 Sel1 repeat TPR_6 PF13174.6 EKX42718.1 - 0.28 11.9 11.5 7.1 7.5 0.1 7.2 9 0 0 9 9 9 0 Tetratricopeptide repeat Sgf11 PF08209.11 EKX42720.1 - 1.3 8.6 4.0 2.5 7.8 4.0 1.4 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) HEAT_2 PF13646.6 EKX42722.1 - 9.1e-22 77.3 6.9 1.2e-08 35.2 0.5 4.4 1 1 3 4 4 4 4 HEAT repeats HEAT PF02985.22 EKX42722.1 - 1.5e-17 62.2 5.5 0.00043 20.3 0.0 7.0 8 0 0 8 8 7 3 HEAT repeat Cnd1 PF12717.7 EKX42722.1 - 4.8e-10 39.7 0.2 0.0016 18.5 0.0 3.6 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EKX42722.1 - 6.3e-07 29.8 8.5 0.004 17.6 0.6 4.8 3 1 1 4 4 4 2 HEAT-like repeat Adaptin_N PF01602.20 EKX42722.1 - 3.3e-06 26.0 0.2 0.043 12.4 0.0 2.3 2 1 0 2 2 2 2 Adaptin N terminal region Cohesin_HEAT PF12765.7 EKX42722.1 - 0.00016 21.9 2.4 0.0073 16.6 0.1 3.8 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion RasGEF_N_2 PF14663.6 EKX42722.1 - 0.0025 18.2 1.1 7.1 7.1 0.0 4.2 3 2 1 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Arm PF00514.23 EKX42722.1 - 0.0044 17.0 0.3 0.56 10.3 0.0 3.7 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 EKX42722.1 - 0.0065 17.1 0.0 7.8 7.2 0.0 3.6 2 2 1 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.16 EKX42722.1 - 0.017 15.7 7.0 1.2 10.1 0.1 4.2 5 0 0 5 5 3 0 PBS lyase HEAT-like repeat DUF4042 PF13251.6 EKX42722.1 - 0.036 13.8 0.8 5.2 6.7 0.0 3.7 2 2 3 5 5 5 0 Domain of unknown function (DUF4042) Nipped-B_C PF12830.7 EKX42722.1 - 0.17 11.8 0.5 9.8 6.1 0.0 3.2 4 0 0 4 4 4 0 Sister chromatid cohesion C-terminus CLASP_N PF12348.8 EKX42722.1 - 0.2 11.2 0.4 8.7 5.8 0.0 2.9 2 2 1 4 4 4 0 CLASP N terminal Phage_holin_3_3 PF16083.5 EKX42723.1 - 0.0084 16.2 3.9 0.33 11.1 0.1 2.4 2 0 0 2 2 2 2 LydA holin phage, holin superfamily III DUF202 PF02656.15 EKX42723.1 - 5.6 7.5 8.1 18 5.9 8.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Death PF00531.22 EKX42724.1 - 0.017 15.3 1.8 0.017 15.3 1.8 1.5 2 0 0 2 2 2 0 Death domain ThiS PF02597.20 EKX42724.1 - 0.066 13.9 0.6 0.52 11.0 0.1 2.2 1 1 0 2 2 2 0 ThiS family Tn7_Tnp_TnsA_C PF08721.11 EKX42724.1 - 0.22 12.2 1.7 0.49 11.1 0.8 2.1 1 1 0 2 2 2 0 TnsA endonuclease C terminal Cupin_8 PF13621.6 EKX42725.1 - 3.3e-18 66.3 1.9 5.8e-18 65.5 1.9 1.4 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EKX42725.1 - 1.6e-17 63.9 0.5 4.7e-17 62.5 0.5 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase SET PF00856.28 EKX42725.1 - 6.8e-09 36.3 0.0 2.5e-08 34.5 0.0 2.1 2 1 0 2 2 2 1 SET domain Cupin_4 PF08007.12 EKX42725.1 - 0.0051 16.3 0.7 0.02 14.4 0.0 2.2 2 1 0 2 2 2 1 Cupin superfamily protein Cupin_6 PF12852.7 EKX42725.1 - 0.0054 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 EKX42725.1 - 0.012 15.3 0.1 0.029 14.1 0.1 1.7 1 0 0 1 1 1 0 Cupin domain DUF4127 PF13552.6 EKX42725.1 - 0.11 11.1 0.0 0.24 10.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) Endonuc-FokI_C PF09254.11 EKX42725.1 - 1.2 8.4 4.0 0.37 10.0 0.1 2.1 2 0 0 2 2 2 0 Restriction endonuclease FokI, C terminal cobW PF02492.19 EKX42726.1 - 3.7e-59 199.3 1.4 4.8e-59 198.9 1.4 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EKX42726.1 - 3.3e-21 75.0 0.0 5.6e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.27 EKX42726.1 - 1.9e-06 27.6 4.1 1.2e-05 24.9 4.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EKX42726.1 - 2.7e-06 27.4 0.3 0.059 13.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EKX42726.1 - 0.0082 16.2 1.7 0.052 13.6 1.7 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 EKX42726.1 - 0.013 15.0 2.1 0.5 9.8 0.4 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family TsaE PF02367.17 EKX42726.1 - 0.014 15.4 0.2 0.031 14.3 0.2 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 EKX42726.1 - 0.027 14.3 0.2 0.096 12.6 0.2 2.0 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.6 EKX42726.1 - 0.11 12.9 0.5 0.22 11.9 0.5 1.8 1 1 0 1 1 1 0 AAA ATPase domain DAP3 PF10236.9 EKX42726.1 - 0.13 11.4 0.3 0.28 10.3 0.3 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 EKX42726.1 - 0.14 11.9 0.2 0.4 10.5 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 EKX42726.1 - 0.15 12.3 0.1 0.38 11.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EKX42726.1 - 0.42 11.1 6.9 2.1 8.8 6.9 2.0 1 1 0 1 1 1 0 AAA domain LysM PF01476.20 EKX42727.1 - 2.8e-09 36.9 0.0 3.2e-05 23.9 0.0 2.8 3 0 0 3 3 3 2 LysM domain Na_H_Exchanger PF00999.21 EKX42729.1 - 4.8e-52 177.0 32.5 6.1e-44 150.3 20.2 2.0 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family DUF4271 PF14093.6 EKX42729.1 - 5.3 6.9 19.1 0.071 13.0 7.2 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF4271) LysM PF01476.20 EKX42731.1 - 9.8e-12 44.8 0.0 2.2e-07 30.8 0.0 2.3 2 0 0 2 2 2 2 LysM domain PDZ PF00595.24 EKX42732.1 - 2.6e-07 30.9 1.1 0.0015 18.8 0.1 2.8 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 EKX42732.1 - 0.00024 20.9 0.2 0.019 14.8 0.1 2.8 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX42732.1 - 0.0069 16.7 0.2 1.6 9.1 0.1 2.5 2 0 0 2 2 2 2 PDZ domain GLTT PF01744.20 EKX42735.1 - 4.2e-06 26.4 6.0 0.059 13.1 0.2 3.4 2 1 1 3 3 3 3 GLTT repeat (6 copies) Pentapeptide_2 PF01469.18 EKX42735.1 - 0.1 12.5 12.8 0.2 11.6 4.3 2.4 1 1 1 2 2 2 0 Pentapeptide repeats (8 copies) DUF2417 PF10329.9 EKX42735.1 - 5.6 6.3 6.6 2.4 7.5 3.3 1.8 1 1 1 2 2 2 0 Region of unknown function (DUF2417) cobW PF02492.19 EKX42736.1 - 1.4e-23 83.4 0.0 2.1e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 EKX42736.1 - 3.8e-07 30.6 0.0 1.4e-06 28.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 EKX42736.1 - 8e-05 21.8 0.1 0.00041 19.5 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 EKX42736.1 - 0.0016 18.7 0.0 0.0036 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.17 EKX42736.1 - 0.0044 17.1 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 EKX42736.1 - 0.0045 16.9 0.0 2 8.3 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase AAA_7 PF12775.7 EKX42736.1 - 0.0056 16.2 0.0 0.0092 15.5 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 EKX42736.1 - 0.0092 15.4 0.1 0.042 13.2 0.0 1.9 2 0 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.14 EKX42736.1 - 0.028 14.3 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.17 EKX42736.1 - 0.041 13.7 0.1 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 EKX42736.1 - 0.047 13.6 0.1 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Viral_helicase1 PF01443.18 EKX42736.1 - 0.048 13.4 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 EKX42736.1 - 0.067 13.4 0.0 0.13 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 EKX42736.1 - 0.084 12.0 0.0 0.33 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 EKX42736.1 - 0.1 13.2 0.0 0.39 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain CobW_C PF07683.14 EKX42736.1 - 0.11 12.4 0.0 1.2 9.1 0.0 2.5 1 1 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain Zeta_toxin PF06414.12 EKX42736.1 - 0.13 11.5 0.0 0.42 9.9 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin TrwB_AAD_bind PF10412.9 EKX42736.1 - 0.15 10.9 0.0 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.6 EKX42736.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Kinesin PF00225.23 EKX42738.1 - 7.8e-94 314.3 1.1 2.2e-62 211.0 0.2 4.7 3 3 2 5 5 5 2 Kinesin motor domain Microtub_bd PF16796.5 EKX42738.1 - 8.8e-26 90.6 2.2 1.9e-25 89.5 0.0 2.6 2 1 0 2 2 2 1 Microtubule binding Arf PF00025.21 EKX42739.1 - 1.7e-41 141.6 0.2 2.2e-40 137.9 0.2 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EKX42739.1 - 2.5e-13 50.3 0.0 3.6e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EKX42739.1 - 1.9e-11 43.7 0.3 1.2e-05 24.7 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EKX42739.1 - 1.9e-10 40.5 0.0 3e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EKX42739.1 - 2.4e-08 33.6 0.0 4.2e-08 32.8 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EKX42739.1 - 2.1e-07 30.6 0.0 5.2e-07 29.3 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EKX42739.1 - 6.1e-06 25.9 0.0 1e-05 25.2 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EKX42739.1 - 1e-05 25.5 0.0 2.8e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EKX42739.1 - 0.00052 20.4 0.7 0.014 15.8 0.7 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EKX42739.1 - 0.015 15.6 0.1 0.03 14.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 EKX42739.1 - 0.019 14.4 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF3352 PF11832.8 EKX42739.1 - 0.02 13.5 0.2 0.026 13.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3352) TniB PF05621.11 EKX42739.1 - 0.021 14.2 0.0 1.8 7.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein NACHT PF05729.12 EKX42739.1 - 0.027 14.4 0.1 0.058 13.3 0.1 1.8 1 1 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 EKX42739.1 - 0.11 13.0 0.5 0.38 11.3 0.1 1.9 2 1 1 3 3 3 0 ABC transporter PDZ_6 PF17820.1 EKX42740.1 - 1.2e-05 25.0 0.0 2.1e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX42740.1 - 0.0013 19.1 0.1 0.0023 18.3 0.1 1.4 1 0 0 1 1 1 1 PDZ domain LST1 PF05083.13 EKX42740.1 - 0.11 12.7 0.3 0.29 11.4 0.0 1.8 2 0 0 2 2 2 0 LST-1 protein OAD_gamma PF04277.13 EKX42740.1 - 8.3 7.1 5.6 16 6.2 0.0 3.1 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Methyltransf_32 PF13679.6 EKX42742.1 - 2e-07 31.2 1.5 8.2e-05 22.6 0.8 2.4 1 1 1 2 2 2 2 Methyltransferase domain Sel1 PF08238.12 EKX42743.1 - 9.9e-13 48.3 11.9 6e-08 33.1 0.1 5.2 5 0 0 5 5 5 2 Sel1 repeat TPR_16 PF13432.6 EKX42743.1 - 0.14 12.9 16.9 0.47 11.2 3.0 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EKX42743.1 - 1.6 8.9 0.0 1.6 8.9 0.0 4.1 5 1 1 6 6 6 0 Tetratricopeptide repeat RWD PF05773.22 EKX42744.1 - 1.5e-07 31.7 0.0 2.4e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 RWD domain COMM_domain PF07258.14 EKX42745.1 - 1.8e-09 37.6 0.1 3.1e-09 36.8 0.1 1.4 1 0 0 1 1 1 1 COMM domain Ion_trans PF00520.31 EKX42746.1 - 1.8e-85 286.1 19.2 1.6e-39 135.6 0.0 3.1 3 0 0 3 3 3 3 Ion transport protein PKD_channel PF08016.12 EKX42746.1 - 0.00069 18.4 40.7 0.0011 17.8 1.4 6.0 5 2 1 6 6 6 3 Polycystin cation channel MscS_porin PF12795.7 EKX42749.1 - 0.037 13.6 4.0 0.057 13.0 4.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain ALMS_motif PF15309.6 EKX42749.1 - 5.7 7.4 10.7 5.8 7.4 1.4 2.5 2 0 0 2 2 2 0 ALMS motif Macoilin PF09726.9 EKX42750.1 - 0.0093 14.6 2.3 0.018 13.6 2.3 1.4 1 0 0 1 1 1 1 Macoilin family zf-ZPR1 PF03367.13 EKX42750.1 - 0.54 10.1 1.7 1.2 9.0 1.2 1.9 2 0 0 2 2 2 0 ZPR1 zinc-finger domain Ku_C PF03730.14 EKX42750.1 - 8.1 7.2 6.9 78 4.1 0.0 3.9 5 0 0 5 5 5 0 Ku70/Ku80 C-terminal arm DUF4646 PF15496.6 EKX42751.1 - 0.72 10.5 3.2 1.5 9.5 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4646) START PF01852.19 EKX42752.1 - 2.1e-12 46.9 0.0 3.1e-09 36.6 0.0 2.1 2 0 0 2 2 2 2 START domain Glyco_transf_25 PF01755.17 EKX42753.1 - 0.00016 21.6 0.0 0.36 10.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Rotamase_3 PF13616.6 EKX42754.1 - 7.1e-20 71.7 0.1 8.5e-20 71.4 0.1 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 EKX42754.1 - 7.9e-19 68.4 0.0 1.1e-18 68.0 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 EKX42754.1 - 0.00017 22.4 0.0 0.00021 22.1 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Cas_Cas7 PF05107.12 EKX42754.1 - 0.033 13.7 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein Cas7 PPR_3 PF13812.6 EKX42755.1 - 0.00012 22.1 0.0 0.015 15.4 0.0 3.0 3 0 0 3 3 3 1 Pentatricopeptide repeat domain KH_1 PF00013.29 EKX42755.1 - 0.00015 21.5 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 KH domain PPR_2 PF13041.6 EKX42755.1 - 0.00083 19.5 2.0 0.023 14.9 0.0 3.7 4 0 0 4 4 4 1 PPR repeat family PPR_long PF17177.4 EKX42755.1 - 0.012 15.0 0.0 0.035 13.5 0.0 1.8 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EKX42755.1 - 0.091 13.1 3.7 42 4.7 0.0 5.1 5 0 0 5 5 5 0 PPR repeat ANAPC5 PF12862.7 EKX42755.1 - 0.12 12.5 0.3 0.35 11.0 0.1 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 FliL PF03748.14 EKX42755.1 - 0.16 12.6 0.1 0.35 11.5 0.1 1.5 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL cNMP_binding PF00027.29 EKX42756.1 - 7.6e-08 32.3 0.0 1.7e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain REJ PF02010.15 EKX42758.1 - 2.5e-39 135.3 6.8 2.5e-39 135.3 6.8 3.7 2 1 1 3 3 3 2 REJ domain DUF4215 PF13948.6 EKX42758.1 - 1.7e-08 34.8 27.2 1e-06 29.0 12.9 7.1 8 0 0 8 8 8 2 Domain of unknown function (DUF4215) EGF_CA PF07645.15 EKX42758.1 - 1.9e-07 31.2 14.8 1.9e-07 31.2 14.8 8.7 9 1 0 9 9 9 1 Calcium-binding EGF domain GPS PF01825.21 EKX42758.1 - 1.1e-05 25.8 0.7 1.1e-05 25.8 0.7 2.9 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif cEGF PF12662.7 EKX42758.1 - 0.075 13.0 10.8 0.027 14.4 0.5 3.7 2 0 0 2 2 2 0 Complement Clr-like EGF-like zinc_ribbon_2 PF13240.6 EKX42758.1 - 0.095 12.4 18.0 0.55 10.0 1.4 4.4 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 EKX42758.1 - 1.8 8.0 31.0 0.039 13.4 3.8 4.6 4 0 0 4 4 4 0 zinc-ribbon domain TRAPP PF04051.16 EKX42759.1 - 2.2e-23 82.6 0.0 2.5e-23 82.4 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF202 PF02656.15 EKX42760.1 - 5.4e-12 46.0 0.4 5.4e-12 46.0 0.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2569 PF10754.9 EKX42760.1 - 2.8e-05 24.6 0.5 3.7e-05 24.2 0.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2569) SLAC1 PF03595.17 EKX42760.1 - 0.0044 16.3 1.1 0.0057 16.0 1.1 1.2 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF3611 PF12263.8 EKX42760.1 - 0.023 14.6 1.2 0.031 14.2 1.2 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3611) TRIQK PF15168.6 EKX42760.1 - 0.057 13.3 0.4 0.089 12.7 0.0 1.4 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family SlyX PF04102.12 EKX42761.1 - 0.57 10.8 3.1 25 5.6 0.1 2.8 3 0 0 3 3 3 0 SlyX PDGF_N PF04692.13 EKX42762.1 - 0.028 15.2 5.9 0.078 13.8 5.9 1.9 1 0 0 1 1 1 0 Platelet-derived growth factor, N terminal region Androgen_recep PF02166.16 EKX42762.1 - 0.22 10.4 11.6 0.32 9.8 11.6 1.2 1 0 0 1 1 1 0 Androgen receptor Zip PF02535.22 EKX42762.1 - 0.83 8.8 2.5 1.3 8.2 2.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Transketolase_N PF00456.21 EKX42763.1 - 2.3e-17 63.0 4.0 8.8e-16 57.8 4.0 2.1 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 EKX42763.1 - 4.3e-11 42.8 0.0 1e-09 38.3 0.0 2.3 2 0 0 2 2 2 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 EKX42763.1 - 2e-07 30.9 0.1 1.6e-05 24.7 0.1 2.3 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.21 EKX42763.1 - 1.8e-06 27.8 0.5 7.1e-06 25.9 0.5 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 EKX42763.1 - 4.5e-05 22.5 0.0 7.4e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component XFP_N PF09364.10 EKX42763.1 - 0.0079 15.0 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 XFP N-terminal domain DXP_synthase_N PF13292.6 EKX42763.1 - 0.11 11.7 0.0 0.31 10.2 0.0 1.6 1 1 1 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase ERCC4 PF02732.15 EKX42764.1 - 9.1e-07 29.2 0.2 2.2e-06 27.9 0.2 1.7 1 0 0 1 1 1 1 ERCC4 domain CpeT PF06206.11 EKX42764.1 - 4e-05 23.6 0.0 9.9e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 CpeT/CpcT family (DUF1001) Med13_N PF11597.8 EKX42764.1 - 0.011 15.1 0.7 0.033 13.6 0.2 1.9 2 0 0 2 2 2 0 Mediator complex subunit 13 N-terminal DUF525 PF04379.14 EKX42764.1 - 0.051 13.8 0.0 0.28 11.4 0.0 2.1 2 0 0 2 2 2 0 ApaG domain NAD_binding_10 PF13460.6 EKX42766.1 - 2.7e-05 24.1 0.0 0.00017 21.5 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding XG_FTase PF03254.13 EKX42767.1 - 0.00011 21.0 0.0 0.00016 20.4 0.0 1.2 1 0 0 1 1 1 1 Xyloglucan fucosyltransferase PSP PF04046.16 EKX42767.1 - 0.1 12.5 0.3 0.24 11.3 0.3 1.6 1 0 0 1 1 1 0 PSP RIH_assoc PF08454.11 EKX42768.1 - 1.7e-12 47.1 0.7 1.7e-12 47.1 0.7 3.3 4 0 0 4 4 4 1 RyR and IP3R Homology associated Ion_trans PF00520.31 EKX42768.1 - 0.012 14.9 11.3 0.54 9.5 9.2 2.6 2 0 0 2 2 2 0 Ion transport protein EF-G-binding_N PF07299.11 EKX42768.1 - 0.062 13.8 2.9 0.51 10.9 0.1 3.4 3 0 0 3 3 3 0 Elongation factor G-binding protein, N-terminal zf-SAP30 PF13866.6 EKX42768.1 - 0.093 12.9 0.1 0.27 11.3 0.1 1.8 1 0 0 1 1 1 0 SAP30 zinc-finger LOH1CR12 PF10158.9 EKX42768.1 - 0.21 11.6 2.3 3.6 7.6 0.4 3.4 3 0 0 3 3 3 0 Tumour suppressor protein Ins145_P3_rec PF08709.11 EKX42769.1 - 7.9e-16 57.9 0.0 8.4e-16 57.8 0.0 1.0 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor Rad51 PF08423.11 EKX42770.1 - 1.3e-123 411.2 1.6 6.5e-122 405.7 1.6 2.2 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 EKX42770.1 - 4.1e-09 36.3 0.2 1.4e-08 34.6 0.2 1.7 1 1 0 1 1 1 1 AAA domain RecA PF00154.21 EKX42770.1 - 9.5e-09 35.1 0.7 7.6e-07 28.9 0.7 2.1 1 1 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 EKX42770.1 - 4.1e-07 30.5 0.2 1.2e-06 29.0 0.1 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 EKX42770.1 - 0.00041 19.8 0.7 0.009 15.4 0.4 2.2 2 0 0 2 2 2 1 KaiC DnaB_C PF03796.15 EKX42770.1 - 0.002 17.5 0.0 0.033 13.5 0.0 2.1 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_28 PF13521.6 EKX42770.1 - 0.0055 17.0 0.2 0.01 16.1 0.2 1.4 1 0 0 1 1 1 1 AAA domain PAXNEB PF05625.11 EKX42770.1 - 0.1 11.7 0.0 0.27 10.3 0.0 1.6 2 0 0 2 2 2 0 PAXNEB protein ssDNA_TraI_N PF18272.1 EKX42770.1 - 0.11 12.5 0.6 0.25 11.4 0.6 1.5 1 0 0 1 1 1 0 single-stranded DNA binding TraI N-terminal subdomain AAA_24 PF13479.6 EKX42770.1 - 0.14 11.9 0.0 0.31 10.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain GvpD PF07088.11 EKX42770.1 - 0.14 10.7 0.0 0.28 9.8 0.0 1.5 1 0 0 1 1 1 0 GvpD gas vesicle protein Peptidase_M23 PF01551.22 EKX42771.1 - 7.1e-17 61.4 0.5 1.3e-16 60.5 0.5 1.4 1 0 0 1 1 1 1 Peptidase family M23 betaPIX_CC PF16523.5 EKX42774.1 - 0.14 12.0 1.7 0.25 11.2 1.3 1.6 2 0 0 2 2 2 0 betaPIX coiled coil LysM PF01476.20 EKX42775.1 - 1.8e-06 27.9 0.0 1.4e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 LysM domain RWP-RK PF02042.15 EKX42776.1 - 2e-16 59.7 0.0 3.4e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX42776.1 - 0.011 15.5 0.2 2.5 8.0 0.0 2.5 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family RWP-RK PF02042.15 EKX42777.1 - 1.1e-16 60.6 0.0 1.6e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX42777.1 - 0.018 14.8 0.5 0.49 10.2 0.1 2.2 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family Methyltransf_16 PF10294.9 EKX42778.1 - 3.9e-13 49.5 0.0 3.2e-12 46.5 0.0 2.0 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EKX42778.1 - 5.9e-06 26.2 0.0 1.1e-05 25.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EKX42778.1 - 5.2e-05 22.8 0.0 8.5e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EKX42778.1 - 0.02 15.6 0.0 0.049 14.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EKX42778.1 - 0.053 13.1 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 EKX42778.1 - 0.063 13.1 0.1 0.089 12.6 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EKX42778.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RWP-RK PF02042.15 EKX42779.1 - 1.4e-16 60.2 0.0 2.1e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain DUF5327 PF17261.2 EKX42779.1 - 0.053 14.3 1.0 0.08 13.7 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5327) Dynein_AAA_lid PF17852.1 EKX42780.1 - 0.13 12.3 0.1 0.34 11.0 0.1 1.6 1 1 1 2 2 2 0 Dynein heavy chain AAA lid domain RWP-RK PF02042.15 EKX42781.1 - 1.8e-16 59.8 0.0 2.9e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX42781.1 - 0.014 15.2 0.2 3 7.7 0.0 2.6 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family ABC_tran PF00005.27 EKX42782.1 - 1.4e-30 106.6 0.0 3.8e-30 105.2 0.0 1.8 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EKX42782.1 - 1.8e-22 80.3 9.5 2.4e-22 79.9 9.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EKX42782.1 - 9.8e-07 28.4 0.1 2.9e-05 23.6 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EKX42782.1 - 2.8e-06 27.8 0.1 2.7e-05 24.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EKX42782.1 - 1.6e-05 25.2 0.5 0.00014 22.2 0.5 2.3 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EKX42782.1 - 0.0026 17.8 0.0 0.018 15.1 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase Cytidylate_kin PF02224.18 EKX42782.1 - 0.0043 16.8 0.3 0.13 12.0 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase Zeta_toxin PF06414.12 EKX42782.1 - 0.0055 16.0 0.0 0.016 14.5 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin RsgA_GTPase PF03193.16 EKX42782.1 - 0.008 16.1 0.6 0.03 14.2 0.0 2.2 3 0 0 3 3 2 1 RsgA GTPase RNA_helicase PF00910.22 EKX42782.1 - 0.018 15.4 0.0 0.049 14.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase DUF87 PF01935.17 EKX42782.1 - 0.027 14.6 0.1 0.058 13.5 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_25 PF13481.6 EKX42782.1 - 0.034 13.7 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 EKX42782.1 - 0.058 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EKX42782.1 - 0.072 13.6 0.4 0.34 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EKX42782.1 - 0.087 12.8 0.1 0.37 10.8 0.0 2.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EKX42782.1 - 0.088 13.0 0.1 0.36 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EKX42782.1 - 0.097 12.4 1.4 0.5 10.1 0.1 2.7 4 0 0 4 4 3 0 P-loop containing region of AAA domain APS_kinase PF01583.20 EKX42782.1 - 0.098 12.5 0.1 0.27 11.1 0.1 1.8 2 0 0 2 2 1 0 Adenylylsulphate kinase AAA_30 PF13604.6 EKX42782.1 - 0.11 12.2 0.2 0.52 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EKX42782.1 - 0.13 12.4 0.0 0.66 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EKX42782.1 - 0.13 12.2 0.0 0.37 10.7 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 EKX42782.1 - 0.22 12.0 0.0 6.1 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain CitMHS PF03600.16 EKX42783.1 - 2.1e-38 132.2 23.2 6.4e-29 101.1 0.3 2.2 2 0 0 2 2 2 2 Citrate transporter TrkA_C PF02080.21 EKX42783.1 - 0.00097 18.9 0.0 2.4 8.0 0.0 3.1 3 0 0 3 3 3 2 TrkA-C domain ELFV_dehydrog PF00208.21 EKX42784.1 - 1.5e-14 54.3 3.9 2.9e-08 33.7 0.1 2.3 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EKX42784.1 - 6.8e-06 26.0 0.0 1.5e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 EKX42784.1 - 0.00099 19.5 0.3 0.0035 17.8 0.1 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 EKX42784.1 - 0.0013 18.1 0.1 0.0032 16.9 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 EKX42784.1 - 0.0037 17.5 0.1 0.0096 16.2 0.1 1.7 1 0 0 1 1 1 1 TrkA-N domain AdoHcyase_NAD PF00670.21 EKX42784.1 - 0.007 16.5 0.8 0.013 15.5 0.2 1.9 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ApbA PF02558.16 EKX42784.1 - 0.02 14.5 0.2 0.039 13.6 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 EKX42784.1 - 0.047 13.0 0.3 0.089 12.1 0.3 1.4 1 0 0 1 1 1 0 ThiF family tRNA_anti-codon PF01336.25 EKX42788.1 - 3.6e-05 23.7 0.0 0.00011 22.1 0.0 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain SAWADEE PF16719.5 EKX42789.1 - 0.02 14.9 0.9 0.11 12.5 0.9 2.2 1 1 0 1 1 1 0 SAWADEE domain DUF4537 PF15057.6 EKX42789.1 - 0.025 14.6 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) KH_1 PF00013.29 EKX42790.1 - 2.1e-07 30.7 1.5 4e-06 26.6 0.4 2.3 2 0 0 2 2 2 2 KH domain NAD_Gly3P_dh_N PF01210.23 EKX42791.1 - 4e-44 150.3 0.0 6.4e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EKX42791.1 - 5.5e-43 146.7 0.0 8.2e-43 146.1 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus ApbA PF02558.16 EKX42791.1 - 1.1e-07 31.6 0.0 1.8e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 EKX42791.1 - 5.8e-06 26.8 0.0 1.8e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 EKX42791.1 - 0.00086 19.2 0.0 0.0023 17.9 0.0 1.7 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PDH PF02153.17 EKX42791.1 - 0.007 15.4 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 EKX42791.1 - 0.036 14.2 0.0 0.11 12.7 0.0 1.8 1 1 1 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase SpoU_methylase PF00588.19 EKX42792.1 - 1.4e-12 48.0 0.1 4.4e-11 43.1 0.0 2.7 2 1 0 2 2 2 1 SpoU rRNA Methylase family Methyltrn_RNA_3 PF02598.17 EKX42792.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methyltransferase Cnd2 PF05786.14 EKX42792.1 - 3.5 6.2 8.1 3.1 6.4 7.8 1.2 1 1 0 1 1 1 0 Condensin complex subunit 2 DUF4200 PF13863.6 EKX42793.1 - 1.6e-21 76.9 23.2 1.6e-21 76.9 23.2 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) Lectin_leg-like PF03388.13 EKX42796.1 - 7.5e-57 192.3 0.0 1.2e-56 191.7 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 EKX42796.1 - 1.7e-09 38.0 0.0 3e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial lectin FUSC PF04632.12 EKX42796.1 - 0.17 10.4 2.9 0.12 10.9 0.2 1.8 2 0 0 2 2 2 0 Fusaric acid resistance protein family Thioredoxin PF00085.20 EKX42797.1 - 1.2e-16 60.6 0.1 1.3e-16 60.5 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 EKX42797.1 - 9.7e-05 22.3 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 EKX42797.1 - 0.00026 21.4 0.3 0.0045 17.4 0.3 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EKX42797.1 - 0.0016 18.5 0.1 0.0019 18.3 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 EKX42797.1 - 0.0018 18.6 0.0 0.0022 18.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 EKX42797.1 - 0.0073 15.7 0.1 0.0076 15.6 0.1 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 EKX42797.1 - 0.03 14.1 0.0 0.034 13.9 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin DDE_Tnp_1_2 PF13586.6 EKX42797.1 - 0.043 14.2 0.0 0.056 13.8 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain IFT57 PF10498.9 EKX42798.1 - 0.0004 19.5 8.7 0.0004 19.5 8.7 7.5 2 2 5 7 7 7 1 Intra-flagellar transport protein 57 CENP-Q PF13094.6 EKX42799.1 - 0.0083 16.3 4.6 0.01 16.0 4.6 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit MADF_DNA_bdg PF10545.9 EKX42799.1 - 0.023 15.0 0.3 0.03 14.6 0.3 1.2 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like ApoO PF09769.9 EKX42799.1 - 0.025 14.5 0.4 0.028 14.4 0.4 1.0 1 0 0 1 1 1 0 Apolipoprotein O Rib PF08428.10 EKX42799.1 - 0.13 12.3 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Rib/alpha-like repeat DCR PF14047.6 EKX42799.1 - 0.18 12.1 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 Dppa2/4 conserved region TPR_1 PF00515.28 EKX42800.1 - 1.3e-07 31.2 2.1 0.0027 17.5 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX42800.1 - 1.3e-07 31.2 3.1 0.0093 16.0 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX42800.1 - 9e-06 26.1 0.0 0.28 12.1 0.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX42800.1 - 4.4e-05 23.7 0.7 0.0036 17.6 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX42800.1 - 0.00012 21.8 1.2 2.1 8.6 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX42800.1 - 0.00013 21.9 3.4 0.24 11.7 0.1 3.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX42800.1 - 0.0004 20.2 0.2 0.028 14.3 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX42800.1 - 0.0037 16.9 0.2 0.55 10.0 0.0 3.3 3 0 0 3 3 3 1 TPR repeat TPR_19 PF14559.6 EKX42800.1 - 0.0075 16.8 0.1 0.13 12.8 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX42800.1 - 0.014 16.0 1.2 0.17 12.6 0.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EKX42800.1 - 0.072 13.5 0.0 5.2 7.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Mito_carr PF00153.27 EKX42801.1 - 3.6e-66 219.1 6.2 1.5e-24 85.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 EKX42802.1 - 1.4e-42 143.5 8.1 5.7e-19 67.8 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein MORN PF02493.20 EKX42803.1 - 2.1e-19 68.2 20.2 3.5e-07 29.7 2.8 5.3 4 0 0 4 4 4 4 MORN repeat PARP PF00644.20 EKX42803.1 - 3.1e-09 36.7 0.0 2.1e-08 34.0 0.0 2.3 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Arm PF00514.23 EKX42805.1 - 6.8e-27 92.6 3.0 2.1e-09 37.1 0.0 5.0 5 0 0 5 5 5 4 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EKX42805.1 - 7.1e-06 26.4 3.9 0.26 11.9 0.1 4.1 3 2 1 4 4 4 2 HEAT-like repeat HEAT_2 PF13646.6 EKX42805.1 - 1.6e-05 25.2 0.7 8.1e-05 22.9 0.0 2.5 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.22 EKX42805.1 - 0.00031 20.7 0.7 3.5 8.1 0.0 3.9 4 0 0 4 4 4 2 HEAT repeat KAP PF05804.12 EKX42805.1 - 0.0011 17.2 0.0 0.0014 16.9 0.0 1.2 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 EKX42805.1 - 0.015 14.7 0.0 0.026 13.8 0.0 1.4 1 1 0 1 1 1 0 V-ATPase subunit H Cnd1 PF12717.7 EKX42805.1 - 0.018 15.1 0.0 1.9 8.5 0.0 2.3 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 ARID PF01388.21 EKX42806.1 - 8.4e-10 39.2 0.0 2.1e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF2749 PF10907.8 EKX42806.1 - 0.023 14.9 0.4 1.9 8.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) HEAT PF02985.22 EKX42808.1 - 0.0027 17.8 0.2 0.94 9.9 0.2 3.4 2 0 0 2 2 2 2 HEAT repeat Rotamase PF00639.21 EKX42809.1 - 5.4e-16 59.3 0.8 2.1e-15 57.4 0.8 1.9 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EKX42809.1 - 2.2e-15 57.2 0.1 3.3e-15 56.6 0.1 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 EKX42809.1 - 1.7e-05 25.6 6.5 0.00047 21.0 6.5 2.0 1 1 0 1 1 1 1 PPIC-type PPIASE domain HTH_psq PF05225.16 EKX42809.1 - 0.0066 16.2 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain Tam41_Mmp37 PF09139.11 EKX42810.1 - 3e-87 293.1 0.0 3.5e-87 292.9 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial LSM PF01423.22 EKX42811.1 - 1.1e-18 66.7 0.1 1.3e-18 66.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain APG6_N PF17675.1 EKX42813.1 - 0.021 15.3 12.3 0.021 15.3 12.3 2.5 1 1 0 2 2 2 0 Apg6 coiled-coil region AAA_16 PF13191.6 EKX42813.1 - 0.033 14.6 0.1 0.19 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 EKX42813.1 - 0.12 12.0 1.9 0.33 10.5 0.0 2.4 3 0 0 3 3 3 0 AAA domain CbiA PF01656.23 EKX42813.1 - 0.13 12.3 0.3 0.72 9.9 0.0 2.2 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DASH_Dam1 PF08653.10 EKX42813.1 - 0.14 12.0 3.4 1.3 8.9 1.1 3.1 2 1 1 3 3 3 0 DASH complex subunit Dam1 AAA_11 PF13086.6 EKX42813.1 - 0.31 10.8 0.0 0.31 10.8 0.0 3.1 2 1 0 2 2 1 0 AAA domain Pox_A_type_inc PF04508.12 EKX42813.1 - 0.4 10.6 4.3 0.39 10.6 1.3 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Vps54_N PF10475.9 EKX42813.1 - 1 8.6 11.0 2.3 7.4 8.1 2.3 2 1 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex WDCP PF15390.6 EKX42813.1 - 1.2 7.4 14.9 1.9 6.8 14.9 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF3450 PF11932.8 EKX42813.1 - 2.1 7.6 24.3 2.2 7.5 6.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) KASH_CCD PF14662.6 EKX42813.1 - 2.6 7.8 38.3 0.23 11.3 12.5 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 EKX42813.1 - 2.7 6.8 37.1 1.1 8.1 7.0 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF16 PF01519.16 EKX42813.1 - 7 7.2 28.6 45 4.6 1.1 3.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF948 PF06103.11 EKX42813.1 - 9.7 6.5 8.4 30 5.0 3.7 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Mito_carr PF00153.27 EKX42814.1 - 7.3e-08 32.2 0.0 1.8e-07 31.0 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial carrier protein Asparaginase_2 PF01112.18 EKX42815.1 - 5e-90 301.6 7.6 6.3e-90 301.3 7.6 1.1 1 0 0 1 1 1 1 Asparaginase Dynamin_N PF00350.23 EKX42816.1 - 8.5e-57 191.9 0.1 1.2e-56 191.4 0.1 1.2 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EKX42816.1 - 6.5e-33 114.2 0.6 2.8e-32 112.1 0.0 2.0 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 EKX42816.1 - 6.3e-06 26.2 0.1 4.4e-05 23.5 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 EKX42816.1 - 0.028 13.8 0.0 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family FeoB_N PF02421.18 EKX42816.1 - 0.078 12.5 0.0 5.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B VirE PF05272.11 EKX42816.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E Fasciclin PF02469.22 EKX42817.1 - 0.004 17.4 0.0 0.0053 17.0 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain DUF2955 PF11168.8 EKX42817.1 - 0.069 13.0 0.3 0.14 12.0 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2955) Pkinase PF00069.25 EKX42818.1 - 4.4e-29 101.6 0.0 6.7e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX42818.1 - 2.1e-17 63.3 0.0 3e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX42818.1 - 1.6e-06 27.7 0.0 2.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EKX42818.1 - 6.1e-05 22.0 0.0 8.4e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RWP-RK PF02042.15 EKX42819.1 - 1.2e-16 60.4 0.0 1.8e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX42820.1 - 6.9e-18 64.4 0.1 1.6e-17 63.2 0.1 1.6 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX42820.1 - 0.64 9.9 1.6 9.9 6.0 0.0 2.7 2 1 1 3 3 3 0 Bacterial regulatory protein, Fis family RWP-RK PF02042.15 EKX42822.1 - 1.1e-16 60.5 0.0 1.8e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 RWP-RK domain HTH_28 PF13518.6 EKX42822.1 - 0.44 10.7 1.4 1.2 9.3 0.0 2.3 3 0 0 3 3 3 0 Helix-turn-helix domain DUF1768 PF08719.11 EKX42824.1 - 1.2e-08 35.4 0.1 2.1e-08 34.6 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1768) DUF1768 PF08719.11 EKX42825.1 - 1.2e-08 35.4 0.1 2.1e-08 34.6 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1768) Dynamin_M PF01031.20 EKX42826.1 - 4e-80 269.1 1.0 7.2e-80 268.2 1.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EKX42826.1 - 3e-47 160.8 0.0 7.1e-47 159.6 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EKX42826.1 - 3.8e-14 52.6 0.5 1.3e-13 50.9 0.5 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EKX42826.1 - 0.0011 19.0 0.0 0.0031 17.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase VirE PF05272.11 EKX42826.1 - 0.021 14.6 0.0 0.059 13.1 0.0 1.7 1 0 0 1 1 1 0 Virulence-associated protein E AF0941-like PF14591.6 EKX42826.1 - 0.033 14.8 0.3 0.8 10.3 0.0 3.3 2 1 2 4 4 4 0 AF0941-like AAA_15 PF13175.6 EKX42826.1 - 0.084 12.6 1.0 2.5 7.7 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain DUF2634 PF10934.8 EKX42827.1 - 0.16 12.1 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2634) Fz PF01392.22 EKX42829.1 - 3.5e-06 27.6 2.8 3.5e-06 27.6 2.8 2.1 1 1 1 2 2 2 1 Fz domain TNFR_16_TM PF18422.1 EKX42829.1 - 0.076 13.0 0.6 0.2 11.6 0.6 1.6 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Transport_MerF PF11431.8 EKX42829.1 - 0.13 12.2 2.5 5.5 7.0 0.2 2.6 2 0 0 2 2 2 0 Membrane transport protein MerF Triabin PF03973.13 EKX42830.1 - 0.084 12.7 0.3 0.11 12.4 0.3 1.1 1 0 0 1 1 1 0 Triabin UPF0223 PF05256.12 EKX42832.1 - 0.018 15.4 0.2 0.25 11.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0223) tRNA-synt_His PF13393.6 EKX42834.1 - 4.6e-43 147.7 0.0 7e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EKX42834.1 - 6.9e-09 35.7 0.8 3.7e-08 33.4 0.1 2.3 2 1 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EKX42834.1 - 2.5e-06 27.6 0.0 4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 EKX42834.1 - 0.0034 16.9 0.0 0.0061 16.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) RecX PF02631.16 EKX42834.1 - 0.018 15.5 0.0 0.043 14.3 0.0 1.6 1 0 0 1 1 1 0 RecX family DUF2452 PF10504.9 EKX42834.1 - 0.068 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) DUF4473 PF14747.6 EKX42834.1 - 0.084 13.4 0.4 0.45 11.1 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) ACT PF01842.25 EKX42834.1 - 1.3 8.9 2.9 37 4.2 0.0 3.6 4 0 0 4 4 4 0 ACT domain WHEP-TRS PF00458.20 EKX42835.1 - 2.8e-06 27.4 10.1 2.8e-06 27.4 10.1 2.2 2 1 0 2 2 2 1 WHEP-TRS domain PP2C_C PF07830.13 EKX42835.1 - 0.38 11.2 3.6 2.4 8.7 0.3 2.2 1 1 1 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain cobW PF02492.19 EKX42836.1 - 2.9e-42 144.2 1.2 5.1e-42 143.4 1.2 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EKX42836.1 - 9.3e-24 83.2 0.1 4.1e-23 81.1 0.1 2.1 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_18 PF13238.6 EKX42836.1 - 0.017 15.7 0.1 0.037 14.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 EKX42836.1 - 0.064 13.2 0.1 0.16 11.9 0.1 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.6 EKX42836.1 - 0.081 13.3 0.7 0.86 10.0 0.1 2.4 2 0 0 2 2 2 0 AAA ATPase domain RNA_binding PF01877.17 EKX42836.1 - 0.1 12.8 0.1 0.31 11.3 0.1 1.7 1 0 0 1 1 1 0 RNA binding GTP_EFTU PF00009.27 EKX42836.1 - 0.11 12.0 0.1 0.92 9.0 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain RVT_3 PF13456.6 EKX42836.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like MeaB PF03308.16 EKX42836.1 - 0.2 10.6 4.3 1.8 7.4 0.3 2.6 3 1 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF1876 PF08962.11 EKX42836.1 - 0.22 11.5 0.9 0.87 9.6 0.2 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1876) UQ_con PF00179.26 EKX42837.1 - 2.2e-25 89.0 0.0 3e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EKX42837.1 - 0.033 14.1 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 UEV domain Peptidase_S41 PF03572.18 EKX42839.1 - 2.6e-23 82.4 0.1 8.9e-18 64.4 0.0 2.3 1 1 1 2 2 2 2 Peptidase family S41 PDZ_6 PF17820.1 EKX42839.1 - 0.00078 19.2 0.1 0.0028 17.5 0.1 2.0 1 0 0 1 1 1 1 PDZ domain SPRY PF00622.28 EKX42840.1 - 0.00049 20.2 0.0 0.0024 18.0 0.0 2.0 1 1 0 1 1 1 1 SPRY domain DUF202 PF02656.15 EKX42841.1 - 4.2e-14 52.7 2.9 4.2e-14 52.7 2.9 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF1673 PF07895.11 EKX42841.1 - 0.0042 16.8 0.0 0.0053 16.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1673) Oxidored_q2 PF00420.24 EKX42841.1 - 0.0043 16.7 0.7 0.032 13.8 0.7 1.9 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Syndecan PF01034.20 EKX42841.1 - 0.035 14.0 3.8 0.99 9.4 3.8 2.4 1 1 0 1 1 1 0 Syndecan domain DUF2644 PF10841.8 EKX42841.1 - 0.044 14.0 0.8 0.12 12.6 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2644) VEGFR-2_TMD PF17988.1 EKX42841.1 - 0.082 12.4 2.1 0.17 11.3 2.1 1.5 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain VTC PF09359.10 EKX42842.1 - 1e-72 244.8 0.0 1.3e-72 244.5 0.0 1.1 1 0 0 1 1 1 1 VTC domain SUB1_ProdP9 PF18213.1 EKX42843.1 - 0.057 13.3 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 eIF-3_zeta PF05091.12 EKX42843.1 - 5.3 5.9 11.5 8.3 5.3 11.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RIX1 PF08167.12 EKX42844.1 - 1.6e-05 24.7 5.2 0.00017 21.4 5.2 1.9 1 1 0 1 1 1 1 rRNA processing/ribosome biogenesis Urb2 PF10441.9 EKX42844.1 - 0.8 9.6 3.9 3.6 7.5 3.9 2.0 1 1 0 1 1 1 0 Urb2/Npa2 family FAM165 PF14981.6 EKX42845.1 - 0.22 11.4 0.9 0.49 10.2 0.2 1.8 2 0 0 2 2 2 0 FAM165 family PDZ PF00595.24 EKX42846.1 - 8.1e-10 38.9 0.1 2e-09 37.6 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX42846.1 - 8.4e-10 38.4 0.1 3e-09 36.6 0.1 2.1 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX42846.1 - 5.7e-06 26.6 0.0 1.2e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain EF-hand_9 PF14658.6 EKX42846.1 - 0.0014 19.0 0.0 0.0031 17.8 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain Urocanase_N PF17391.2 EKX42846.1 - 0.022 14.5 0.5 66 3.2 0.0 3.7 3 0 0 3 3 3 0 Urocanase N-terminal domain HTH_39 PF14090.6 EKX42846.1 - 0.027 14.2 27.9 26 4.6 0.1 10.2 10 0 0 10 10 10 0 Helix-turn-helix domain RsmJ PF04378.13 EKX42846.1 - 0.57 9.4 14.5 43 3.2 0.1 5.9 6 0 0 6 6 6 0 Ribosomal RNA large subunit methyltransferase D, RlmJ SnoaL_2 PF12680.7 EKX42846.1 - 0.84 10.3 40.1 39 5.0 0.3 9.7 7 4 1 8 8 8 0 SnoaL-like domain JIP_LZII PF16471.5 EKX42847.1 - 0.14 12.4 3.2 0.33 11.2 0.5 2.0 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Spc42p PF11544.8 EKX42849.1 - 0.0048 16.9 35.2 2.3 8.3 0.9 7.2 5 0 0 5 5 5 4 Spindle pole body component Spc42p zf-C2H2_12 PF18658.1 EKX42849.1 - 0.098 12.2 0.8 0.59 9.8 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger C2H2-type Alanine_zipper PF11839.8 EKX42849.1 - 1.1 9.7 135.3 0.094 13.1 27.0 8.0 5 2 2 7 7 7 0 Alanine-zipper, major outer membrane lipoprotein DASH_Dad1 PF08649.10 EKX42849.1 - 1.8 8.8 4.3 1.3e+02 2.8 0.0 3.7 2 0 0 2 2 2 0 DASH complex subunit Dad1 EcoEI_R_C PF08463.10 EKX42849.1 - 6.3 6.9 74.9 0.096 12.8 9.1 7.8 4 3 3 7 7 7 0 EcoEI R protein C-terminal WD40 PF00400.32 EKX42850.1 - 7.3e-12 45.6 14.2 0.015 16.1 1.0 6.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX42850.1 - 0.0014 18.9 1.5 4.6 7.6 0.0 4.4 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain CHB_HEX_C PF03174.13 EKX42850.1 - 0.041 13.9 0.0 2.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain WD40_like PF17005.5 EKX42850.1 - 0.18 11.1 1.3 0.74 9.1 0.1 2.3 3 0 0 3 3 3 0 WD40-like domain F5_F8_type_C PF00754.25 EKX42851.1 - 0.013 15.6 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 F5/8 type C domain DnaJ_CXXCXGXG PF00684.19 EKX42853.1 - 0.011 16.0 27.9 0.011 16.0 27.9 5.0 1 1 3 4 4 4 0 DnaJ central domain Sel1 PF08238.12 EKX42854.1 - 1.1e-25 89.5 21.9 8.7e-09 35.8 0.3 5.8 6 0 0 6 6 6 5 Sel1 repeat SNAP PF14938.6 EKX42855.1 - 3.6e-06 26.6 4.5 4e-06 26.5 2.0 2.2 1 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP FR47 PF08445.10 EKX42855.1 - 0.16 11.9 0.0 0.77 9.8 0.0 2.1 2 0 0 2 2 2 0 FR47-like protein DUF1664 PF07889.12 EKX42856.1 - 0.00042 20.3 6.6 0.00042 20.3 6.6 3.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) KASH_CCD PF14662.6 EKX42856.1 - 0.00044 20.1 35.8 0.00077 19.3 17.0 3.0 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 EKX42856.1 - 0.00054 18.9 40.1 0.0057 15.6 26.0 2.3 1 1 1 2 2 2 2 Spc7 kinetochore protein Tropomyosin PF00261.20 EKX42856.1 - 0.004 16.6 47.0 0.25 10.7 13.4 2.7 1 1 1 2 2 2 2 Tropomyosin TACC_C PF05010.14 EKX42856.1 - 0.0049 16.7 33.0 0.18 11.6 12.0 3.1 1 1 1 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF3584 PF12128.8 EKX42856.1 - 0.0063 14.1 39.3 0.0077 13.8 39.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF4407 PF14362.6 EKX42856.1 - 0.015 14.6 35.5 0.35 10.2 17.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4618 PF15397.6 EKX42856.1 - 0.015 14.7 31.2 0.1 12.0 17.2 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) Fib_alpha PF08702.10 EKX42856.1 - 0.019 15.2 11.0 0.019 15.2 11.0 3.0 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family ADIP PF11559.8 EKX42856.1 - 0.021 14.9 39.1 0.041 14.0 21.5 3.0 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Lectin_N PF03954.14 EKX42856.1 - 0.024 14.4 20.0 0.1 12.4 5.9 3.4 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain FAM76 PF16046.5 EKX42856.1 - 0.031 13.7 30.4 0.024 14.0 16.9 2.8 2 1 0 2 2 2 0 FAM76 protein HMMR_N PF15905.5 EKX42856.1 - 0.031 13.7 41.0 0.052 13.0 12.6 3.0 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal FH2 PF02181.23 EKX42856.1 - 0.032 13.4 19.2 0.059 12.5 8.9 2.6 1 1 1 2 2 2 0 Formin Homology 2 Domain Myosin_tail_1 PF01576.19 EKX42856.1 - 0.047 11.5 43.1 0.02 12.7 11.7 1.7 1 1 0 1 1 1 0 Myosin tail AAA_13 PF13166.6 EKX42856.1 - 0.066 11.8 29.1 0.64 8.6 11.8 2.1 1 1 1 2 2 2 0 AAA domain Bacillus_HBL PF05791.11 EKX42856.1 - 0.07 12.9 15.2 0.57 10.0 0.7 2.5 1 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Uso1_p115_C PF04871.13 EKX42856.1 - 0.077 13.4 49.6 1.4 9.3 14.3 3.6 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Tropomyosin_1 PF12718.7 EKX42856.1 - 0.081 13.1 50.1 2.9 8.0 15.6 3.8 1 1 2 3 3 3 0 Tropomyosin like Fez1 PF06818.15 EKX42856.1 - 0.094 13.2 38.3 0.2 12.1 17.3 2.2 1 1 1 2 2 2 0 Fez1 DUF3573 PF12097.8 EKX42856.1 - 0.097 11.5 1.1 0.13 11.0 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Golgin_A5 PF09787.9 EKX42856.1 - 0.2 11.1 42.1 0.39 10.1 22.4 2.5 1 1 1 2 2 2 0 Golgin subfamily A member 5 FliJ PF02050.16 EKX42856.1 - 0.22 11.8 39.0 1.4 9.1 14.3 3.3 1 1 2 3 3 3 0 Flagellar FliJ protein Lebercilin PF15619.6 EKX42856.1 - 0.23 11.1 43.8 1 9.0 6.4 2.9 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Baculo_PEP_C PF04513.12 EKX42856.1 - 0.27 11.3 17.0 0.39 10.8 9.6 2.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CC2-LZ PF16516.5 EKX42856.1 - 0.39 11.1 34.8 0.5 10.8 5.9 4.4 1 1 4 5 5 5 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF2400 PF09674.10 EKX42856.1 - 0.4 10.7 5.6 0.17 11.9 2.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2400) EzrA PF06160.12 EKX42856.1 - 0.52 8.4 30.0 0.17 10.0 16.0 2.3 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Flagellin_C PF00700.21 EKX42856.1 - 0.61 10.5 11.5 0.31 11.4 2.9 3.3 2 2 1 3 3 3 0 Bacterial flagellin C-terminal helical region DUF812 PF05667.11 EKX42856.1 - 0.67 8.8 34.9 1.1 8.1 34.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FAM184 PF15665.5 EKX42856.1 - 0.71 9.6 42.3 0.35 10.6 13.5 2.8 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B PPE PF00823.19 EKX42856.1 - 0.72 9.9 5.8 0.44 10.6 1.8 2.5 2 1 1 3 3 2 0 PPE family Atg14 PF10186.9 EKX42856.1 - 0.89 8.6 37.5 0.054 12.6 19.8 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Gp58 PF07902.11 EKX42856.1 - 0.9 7.8 12.7 2.5 6.3 12.7 1.7 1 1 0 1 1 1 0 gp58-like protein CLZ PF16526.5 EKX42856.1 - 0.98 9.8 35.6 2.2 8.7 5.1 4.8 3 3 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 EKX42856.1 - 1 9.9 17.6 0.6 10.6 0.2 4.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Fzo_mitofusin PF04799.13 EKX42856.1 - 1 8.9 26.6 0.16 11.5 7.8 3.5 1 1 2 4 4 4 0 fzo-like conserved region ALIX_LYPXL_bnd PF13949.6 EKX42856.1 - 1.8 7.8 31.7 0.011 15.1 18.7 2.1 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV Nup88 PF10168.9 EKX42856.1 - 2.1 6.1 24.9 2.5 5.8 24.9 1.1 1 0 0 1 1 1 0 Nuclear pore component OmpH PF03938.14 EKX42856.1 - 2.3 8.6 43.4 1.8e+04 -11.4 43.4 3.5 1 1 0 1 1 0 0 Outer membrane protein (OmpH-like) Filament PF00038.21 EKX42856.1 - 2.3 7.7 37.9 1.1e+02 2.2 37.9 2.5 1 1 0 1 1 1 0 Intermediate filament protein FlaC_arch PF05377.11 EKX42856.1 - 2.6 8.5 23.1 0.81 10.1 0.6 5.5 2 2 5 7 7 7 0 Flagella accessory protein C (FlaC) Occludin_ELL PF07303.13 EKX42856.1 - 2.7 8.8 20.8 0.17 12.6 5.1 3.4 1 1 1 3 3 3 0 Occludin homology domain THOC7 PF05615.13 EKX42856.1 - 3.1 8.1 36.9 0.83 9.9 2.6 3.3 1 1 2 3 3 3 0 Tho complex subunit 7 TPR_MLP1_2 PF07926.12 EKX42856.1 - 4 7.5 49.0 5 7.2 1.8 3.7 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein ApoO PF09769.9 EKX42856.1 - 4.4 7.3 11.2 33 4.5 0.1 3.3 2 1 1 3 3 3 0 Apolipoprotein O SPATA24 PF15175.6 EKX42856.1 - 5.3 6.9 24.2 4.3 7.2 14.4 2.3 2 0 0 2 2 2 0 Spermatogenesis-associated protein 24 DUF16 PF01519.16 EKX42856.1 - 5.5 7.5 26.5 1.8 9.1 3.8 3.4 1 1 2 3 3 3 0 Protein of unknown function DUF16 Syntaxin-6_N PF09177.11 EKX42856.1 - 6.4 7.4 28.6 37 5.0 2.8 3.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Muted PF14942.6 EKX42856.1 - 7.3 6.9 32.1 2.1 8.7 6.4 3.2 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein COG2 PF06148.11 EKX42856.1 - 8.9 6.4 29.4 3.4 7.8 2.3 4.4 1 1 4 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 XhlA PF10779.9 EKX42856.1 - 8.9 6.6 27.0 1.6 9.0 0.9 4.9 2 2 3 5 5 5 0 Haemolysin XhlA Exonuc_VII_L PF02601.15 EKX42856.1 - 9 5.8 30.5 8.2 5.9 10.8 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit FPP PF05911.11 EKX42856.1 - 9.1 4.3 34.3 5.1 5.1 26.1 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil MAD PF05557.13 EKX42856.1 - 9.5 4.4 38.1 0.27 9.6 13.4 2.2 1 1 1 2 2 2 0 Mitotic checkpoint protein VWA_2 PF13519.6 EKX42857.1 - 0.00028 21.5 0.0 0.00064 20.3 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain N6_N4_Mtase PF01555.18 EKX42858.1 - 0.062 13.0 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 DNA methylase PKD_channel PF08016.12 EKX42859.1 - 1.2e-13 50.5 6.0 1.2e-13 50.5 6.0 2.3 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 EKX42859.1 - 4.1e-07 29.5 3.9 9.6e-07 28.3 3.9 1.6 1 0 0 1 1 1 1 Ion transport protein Laminin_G_3 PF13385.6 EKX42859.1 - 0.00012 22.2 0.6 0.69 10.1 0.3 3.1 3 1 0 3 3 3 2 Concanavalin A-like lectin/glucanases superfamily DUF4083 PF13314.6 EKX42859.1 - 0.35 10.9 4.7 0.89 9.5 4.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) AcylCoA_dehyd_C PF12186.8 EKX42862.1 - 0.19 11.9 0.6 2.5 8.2 0.7 2.1 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal MOZ_SAS PF01853.18 EKX42867.1 - 2.3e-80 268.5 0.1 3e-80 268.1 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EKX42867.1 - 1.4e-17 63.0 0.4 2.9e-17 62.0 0.4 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 EKX42867.1 - 0.0058 17.0 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_16 PF05301.11 EKX42867.1 - 0.013 15.3 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 V_ATPase_prox PF18274.1 EKX42867.1 - 0.017 15.1 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 Vacuolar ATPase Subunit I N-terminal proximal lobe CHAT PF12770.7 EKX42868.1 - 1.9e-05 24.3 0.3 0.00015 21.3 0.2 2.2 1 1 0 1 1 1 1 CHAT domain Cbl_N2 PF02761.14 EKX42868.1 - 0.00045 20.9 0.1 0.0014 19.3 0.1 1.9 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain zf-ribbon_3 PF13248.6 EKX42868.1 - 0.0005 19.4 1.7 0.0012 18.2 1.7 1.7 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 EKX42868.1 - 0.0014 18.6 0.6 0.0014 18.6 0.6 2.1 2 0 0 2 2 2 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 EKX42868.1 - 0.0064 17.2 0.3 0.043 14.6 0.1 2.3 2 0 0 2 2 2 1 zinc-ribbon family SprT-like PF10263.9 EKX42870.1 - 6.4e-23 80.8 0.0 1.7e-22 79.4 0.0 1.7 1 1 1 2 2 2 1 SprT-like family Zn_ribbon_SprT PF17283.2 EKX42870.1 - 0.00095 19.0 3.1 0.002 18.0 3.1 1.6 1 0 0 1 1 1 1 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 EKX42870.1 - 0.04 14.0 3.4 0.092 12.9 3.4 1.6 1 0 0 1 1 1 0 Zinc ribbon domain SHMT PF00464.19 EKX42872.1 - 1e-188 627.0 0.0 1.2e-188 626.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.19 EKX42872.1 - 0.018 14.0 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Ribosomal_S10 PF00338.22 EKX42873.1 - 8.2e-26 90.1 0.1 1e-25 89.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Acetyltransf_10 PF13673.7 EKX42874.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HrpJ PF07201.11 EKX42874.1 - 1.6 9.0 5.0 0.91 9.8 0.3 2.5 3 0 0 3 3 3 0 HrpJ-like domain adh_short PF00106.25 EKX42875.1 - 3.1e-60 203.0 1.4 4.2e-60 202.6 1.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EKX42875.1 - 7.9e-51 172.9 0.6 9.7e-51 172.6 0.6 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX42875.1 - 5.5e-11 42.7 0.2 1.1e-10 41.7 0.2 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EKX42875.1 - 1.9e-05 24.0 0.3 2.3e-05 23.7 0.3 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 EKX42875.1 - 0.00015 21.9 0.4 0.00031 20.8 0.4 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EKX42875.1 - 0.00024 21.4 0.2 0.00049 20.4 0.2 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 EKX42875.1 - 0.0004 20.3 0.9 0.00051 20.0 0.3 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EKX42875.1 - 0.0011 18.4 0.9 0.0029 17.0 0.3 2.0 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EKX42875.1 - 0.0017 18.4 0.1 0.003 17.6 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_10 PF13460.6 EKX42875.1 - 0.0032 17.4 0.1 0.0047 16.8 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Cyclin_N2 PF16500.5 EKX42875.1 - 0.014 16.2 0.2 1.7 9.4 0.1 2.2 2 0 0 2 2 2 0 N-terminal region of cyclin_N THF_DHG_CYH_C PF02882.19 EKX42875.1 - 0.025 13.9 0.1 0.048 13.0 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 EKX42875.1 - 0.033 13.7 0.2 0.066 12.7 0.2 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 EKX42875.1 - 0.057 13.9 0.5 0.29 11.6 0.8 1.9 2 1 0 2 2 2 0 Putative NAD(P)-binding ADH_zinc_N PF00107.26 EKX42875.1 - 0.068 13.2 0.1 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ApbA PF02558.16 EKX42875.1 - 0.096 12.3 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF3683 PF12447.8 EKX42876.1 - 0.043 14.0 1.1 0.043 14.0 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3683) RWP-RK PF02042.15 EKX42877.1 - 1e-16 60.7 0.0 1.6e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain zf-UBP_var PF17807.1 EKX42877.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Variant UBP zinc finger RWP-RK PF02042.15 EKX42878.1 - 2.3e-16 59.5 0.0 3.8e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX42879.1 - 8e-17 61.0 0.0 1.6e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain zf-UBP_var PF17807.1 EKX42879.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Variant UBP zinc finger Herpes_pp85 PF04637.12 EKX42879.1 - 0.19 10.1 0.7 0.22 9.9 0.7 1.0 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Mito_carr PF00153.27 EKX42880.1 - 4e-28 97.2 0.6 3.2e-11 43.0 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein PhzC-PhzF PF02567.16 EKX42883.1 - 1.6e-55 188.6 0.0 1.9e-55 188.3 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Sod_Fe_C PF02777.18 EKX42884.1 - 1.4e-35 121.6 1.6 1.5e-35 121.4 0.1 1.8 3 0 0 3 3 3 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EKX42884.1 - 2.9e-29 101.4 1.2 5.2e-29 100.6 1.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Bac_surface_Ag PF01103.23 EKX42885.1 - 9.1e-15 55.0 0.1 1.2e-14 54.5 0.1 1.1 1 0 0 1 1 1 1 Surface antigen Rhodanese_C PF12368.8 EKX42886.1 - 3.7e-13 49.6 4.1 3.7e-13 49.6 4.1 1.8 2 0 0 2 2 2 1 Rhodanase C-terminal UPF0176_N PF17773.1 EKX42886.1 - 6.5e-12 45.7 0.0 1e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain RWP-RK PF02042.15 EKX42887.1 - 2.9e-15 56.0 0.1 4.3e-15 55.4 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain Sel1 PF08238.12 EKX42888.1 - 2e-35 120.4 22.1 6.2e-10 39.4 1.4 6.2 6 0 0 6 6 6 5 Sel1 repeat TPR_6 PF13174.6 EKX42888.1 - 0.00016 22.1 11.8 0.86 10.4 0.3 5.4 5 1 0 5 5 5 3 Tetratricopeptide repeat Tai4 PF16695.5 EKX42888.1 - 0.1 13.1 2.2 18 5.9 0.1 3.7 1 1 2 3 3 3 0 Type VI secretion system (T6SS), amidase immunity protein ANAPC3 PF12895.7 EKX42888.1 - 0.12 12.6 8.0 0.4 10.9 0.5 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EKX42888.1 - 1.1 9.9 13.0 0.26 11.9 1.9 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat CD225 PF04505.12 EKX42889.1 - 0.0041 17.2 0.2 0.088 13.0 0.0 2.2 2 0 0 2 2 2 1 Interferon-induced transmembrane protein WD40 PF00400.32 EKX42891.1 - 1.2e-26 92.5 19.9 7e-08 33.0 0.0 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 EKX42891.1 - 0.00016 20.3 0.8 0.029 12.9 0.1 2.6 1 1 2 3 3 3 3 Cytochrome D1 heme domain Nup160 PF11715.8 EKX42891.1 - 0.0022 16.7 3.9 0.59 8.7 0.0 3.7 2 2 1 3 3 3 2 Nucleoporin Nup120/160 CIDE-N PF02017.15 EKX42891.1 - 0.0033 17.4 1.4 1.7 8.7 0.1 3.8 1 1 3 4 4 4 1 CIDE-N domain ANAPC4_WD40 PF12894.7 EKX42891.1 - 0.011 16.0 5.6 15 5.9 0.1 4.0 1 1 3 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DUF5570 PF17731.1 EKX42891.1 - 0.22 11.6 4.1 0.13 12.4 1.0 2.3 1 1 1 3 3 3 0 Family of unknown function (DUF5570) Pkinase_Tyr PF07714.17 EKX42892.1 - 1.9e-55 188.0 0.6 9.1e-55 185.7 0.6 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX42892.1 - 4.9e-20 72.0 0.0 2.7e-19 69.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain RWP-RK PF02042.15 EKX42893.1 - 5e-13 48.8 0.0 9.2e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_24 PF13412.6 EKX42893.1 - 0.022 14.3 0.1 0.046 13.3 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.12 EKX42893.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_6 PF01418.17 EKX42893.1 - 0.14 12.2 0.1 0.27 11.3 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_8 PF02954.19 EKX42893.1 - 0.17 11.7 0.0 0.61 9.9 0.0 1.9 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family GST_C PF00043.25 EKX42895.1 - 3.3e-11 43.2 0.0 5e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EKX42895.1 - 1.8e-09 37.7 0.0 2.2e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EKX42895.1 - 6.3e-08 32.5 0.2 9e-08 32.0 0.2 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EKX42895.1 - 0.00082 19.1 0.1 0.0013 18.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EKX42895.1 - 0.013 15.9 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EKX42895.1 - 0.093 13.2 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Copine PF07002.16 EKX42896.1 - 4.7e-74 248.5 0.0 6.4e-74 248.1 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 EKX42896.1 - 1.3e-24 86.4 0.2 5.3e-12 45.9 0.1 2.4 2 0 0 2 2 2 2 C2 domain WW PF00397.26 EKX42896.1 - 2.4e-15 56.3 2.3 5.2e-15 55.2 2.3 1.6 1 0 0 1 1 1 1 WW domain vWA-TerF-like PF10138.9 EKX42896.1 - 9e-06 25.9 0.0 1.8e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus Peptidase_C10 PF01640.17 EKX42897.1 - 0.48 10.7 6.1 1.2 9.4 3.8 2.0 1 1 1 2 2 2 0 Peptidase C10 family SpoU_methylase PF00588.19 EKX42898.1 - 1.1e-25 90.4 0.0 1.8e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family DIRP PF06584.13 EKX42898.1 - 0.0028 17.8 0.0 0.0047 17.1 0.0 1.3 1 0 0 1 1 1 1 DIRP Fucokinase PF07959.12 EKX42899.1 - 9.1e-97 324.6 0.0 1.1e-96 324.3 0.0 1.1 1 0 0 1 1 1 1 L-fucokinase Hexapep PF00132.24 EKX42899.1 - 0.0011 18.6 0.3 0.011 15.4 0.0 2.4 2 0 0 2 2 2 1 Bacterial transferase hexapeptide (six repeats) TFB6 PF17110.5 EKX42899.1 - 0.077 12.7 0.0 0.24 11.1 0.0 1.8 2 1 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH MORN PF02493.20 EKX42900.1 - 1.5e-45 150.4 34.5 1.1e-07 31.3 3.1 7.0 7 0 0 7 7 7 7 MORN repeat DUF1419 PF07215.11 EKX42900.1 - 0.26 11.4 5.2 11 6.1 0.0 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF1419) DHC PF09626.10 EKX42901.1 - 0.064 14.1 0.0 0.078 13.9 0.0 1.2 1 0 0 1 1 1 0 Dihaem cytochrome c Med14 PF08638.11 EKX42901.1 - 0.065 12.7 0.0 0.073 12.5 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit MED14 H-kinase_dim PF02895.14 EKX42901.1 - 0.069 13.6 0.0 0.09 13.2 0.0 1.3 1 0 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain FapA PF03961.13 EKX42901.1 - 0.13 10.9 0.0 0.13 10.8 0.0 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Sulfate_transp PF00916.20 EKX42902.1 - 2.7e-45 154.8 15.4 3.2e-45 154.5 15.4 1.0 1 0 0 1 1 1 1 Sulfate permease family TPR_17 PF13431.6 EKX42904.1 - 5.4e-24 82.8 4.0 0.00061 20.0 0.1 8.7 8 1 0 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 EKX42904.1 - 9.7e-22 75.8 10.3 0.0049 17.6 0.1 8.6 4 3 4 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 EKX42904.1 - 4.6e-21 73.2 21.8 0.0015 18.5 0.2 9.6 8 2 1 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.28 EKX42904.1 - 4.7e-21 73.7 25.6 0.00013 21.6 0.8 9.7 9 2 0 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 EKX42904.1 - 3.6e-20 72.2 13.8 0.029 14.9 0.1 7.5 4 2 3 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 EKX42904.1 - 2.8e-18 64.5 13.4 0.04 14.1 0.1 9.1 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX42904.1 - 2.1e-16 59.3 14.3 0.00032 20.3 0.0 7.8 9 0 0 9 9 8 4 TPR repeat TPR_12 PF13424.6 EKX42904.1 - 3.9e-16 59.1 18.8 0.00016 21.9 0.2 6.8 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 EKX42904.1 - 2.5e-13 50.4 10.6 0.001 19.6 0.0 7.0 5 3 2 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX42904.1 - 2.2e-11 42.9 15.2 0.88 9.7 0.1 8.0 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 EKX42904.1 - 7.5e-11 42.0 6.0 0.066 13.4 0.0 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX42904.1 - 2.8e-06 27.3 10.5 0.068 13.3 0.2 6.8 6 1 1 7 7 7 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 EKX42904.1 - 4.3e-06 27.0 17.2 0.22 12.3 0.0 6.8 8 0 0 8 8 6 2 Tetratricopeptide repeat TPPII_N PF12583.8 EKX42904.1 - 0.00011 22.8 3.6 1.1 9.8 0.0 4.1 4 1 0 4 4 4 2 Tripeptidyl peptidase II N terminal Spt20 PF12090.8 EKX42904.1 - 0.00025 20.7 15.4 0.00025 20.7 15.4 1.8 2 0 0 2 2 2 1 Spt20 family Sel1 PF08238.12 EKX42904.1 - 0.00031 21.3 10.5 13 6.6 0.0 6.5 6 1 0 6 6 6 0 Sel1 repeat TPR_10 PF13374.6 EKX42904.1 - 0.0008 19.2 18.0 6.9 6.7 0.1 8.0 9 0 0 9 9 8 0 Tetratricopeptide repeat Coatomer_E PF04733.14 EKX42904.1 - 0.0014 18.1 3.2 0.24 10.8 0.0 3.9 3 2 1 4 4 4 1 Coatomer epsilon subunit ANAPC3 PF12895.7 EKX42904.1 - 0.0062 16.7 13.1 0.12 12.7 0.3 4.3 3 1 2 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 BAT2_N PF07001.11 EKX42904.1 - 0.0078 16.7 2.9 0.016 15.7 2.9 1.5 1 0 0 1 1 1 1 BAT2 N-terminus DUF2207 PF09972.9 EKX42904.1 - 0.016 14.0 0.0 0.029 13.2 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) GMC_oxred_N PF00732.19 EKX42904.1 - 0.026 13.9 1.3 0.047 13.1 1.1 1.5 1 1 0 1 1 1 0 GMC oxidoreductase Orf78 PF06024.12 EKX42904.1 - 0.1 12.9 1.3 0.28 11.5 1.3 1.7 1 0 0 1 1 1 0 Orf78 (ac78) eIF-3_zeta PF05091.12 EKX42904.1 - 0.16 10.9 9.6 0.018 14.0 5.0 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TAF1_subA PF14929.6 EKX42904.1 - 0.25 10.7 14.6 0.093 12.1 0.7 4.0 4 1 1 5 5 5 0 TAF RNA Polymerase I subunit A DUF913 PF06025.12 EKX42904.1 - 0.45 9.4 6.3 0.075 12.0 1.7 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) EIIBC-GUT_N PF03612.14 EKX42904.1 - 1 9.1 10.1 0.27 11.0 4.9 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Presenilin PF01080.17 EKX42904.1 - 1.1 7.9 10.2 0.12 11.2 5.0 1.8 2 0 0 2 2 2 0 Presenilin RNase_H2_suC PF08615.11 EKX42904.1 - 1.1 9.4 5.8 0.61 10.3 3.4 1.7 2 0 0 2 2 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Zip PF02535.22 EKX42904.1 - 1.2 8.3 3.4 2 7.6 3.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Eapp_C PF10238.9 EKX42904.1 - 1.4 9.0 11.8 0.27 11.3 4.2 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein RR_TM4-6 PF06459.12 EKX42904.1 - 2.4 7.9 11.5 0.079 12.8 4.4 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 FAM176 PF14851.6 EKX42904.1 - 3.3 7.3 9.8 2.4 7.8 4.9 2.4 2 0 0 2 2 2 0 FAM176 family Neur_chan_memb PF02932.16 EKX42904.1 - 4.1 7.4 4.9 1.5 8.9 1.5 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Connexin PF00029.19 EKX42904.1 - 5.1 6.8 8.5 0.32 10.7 2.2 2.0 2 0 0 2 2 2 0 Connexin Kei1 PF08552.11 EKX42904.1 - 7.2 6.4 6.1 0.5 10.2 0.9 1.7 2 0 0 2 2 1 0 Inositolphosphorylceramide synthase subunit Kei1 Pex14_N PF04695.13 EKX42904.1 - 7.4 7.2 15.7 0.43 11.2 9.7 1.9 2 0 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sel1 PF08238.12 EKX42905.1 - 4e-36 122.6 13.5 7e-09 36.1 1.0 5.2 5 0 0 5 5 5 5 Sel1 repeat TPR_12 PF13424.6 EKX42905.1 - 1.9e-05 24.8 0.8 0.18 12.1 0.0 3.8 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX42905.1 - 0.001 18.9 0.7 5 7.4 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Msg2_C PF12373.8 EKX42905.1 - 0.016 14.6 1.4 0.11 11.9 0.1 2.6 2 1 0 2 2 2 0 Major surface glycoprotein 2 C terminal TPR_6 PF13174.6 EKX42905.1 - 0.026 15.2 2.1 21 6.0 0.6 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX42905.1 - 0.049 13.5 11.6 0.57 10.1 0.5 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat PvlArgDC PF01862.16 EKX42905.1 - 0.073 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) TPR_8 PF13181.6 EKX42905.1 - 0.097 12.9 12.0 24 5.5 0.1 6.1 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 EKX42905.1 - 1.5 9.1 19.9 1.9 8.8 0.2 5.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 EKX42905.1 - 2 9.1 7.6 9 7.0 2.1 3.4 1 1 3 4 4 4 0 Tetratricopeptide repeat Carn_acyltransf PF00755.20 EKX42906.1 - 6.9e-171 569.8 0.0 8.1e-171 569.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase TauE PF01925.19 EKX42907.1 - 4.3e-16 59.3 0.6 5.4e-16 59.0 0.6 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE BTP PF05232.12 EKX42907.1 - 0.31 11.1 0.2 0.31 11.1 0.2 1.9 2 0 0 2 2 2 0 Chlorhexidine efflux transporter MORN PF02493.20 EKX42908.1 - 3e-08 33.1 4.8 0.0022 17.8 1.7 2.6 2 0 0 2 2 2 2 MORN repeat PA PF02225.22 EKX42908.1 - 7.8e-08 32.2 0.4 1.5e-07 31.3 0.4 1.4 1 0 0 1 1 1 1 PA domain DUF481 PF04338.12 EKX42909.1 - 0.022 14.8 0.1 3.6 7.6 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function, DUF481 Porin_3 PF01459.22 EKX42909.1 - 0.13 11.7 0.8 0.96 8.9 0.6 2.0 1 1 1 2 2 2 0 Eukaryotic porin EF-hand_6 PF13405.6 EKX42911.1 - 1.5e-11 43.2 2.2 3e-06 26.7 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EKX42911.1 - 2.9e-09 35.8 4.1 6.7e-07 28.4 0.3 3.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EKX42911.1 - 5.4e-08 33.2 5.9 1.2e-07 32.1 4.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX42911.1 - 5.5e-07 28.8 6.4 5.6e-06 25.6 0.2 3.0 3 1 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EKX42911.1 - 3.1e-06 26.9 5.2 2.3e-05 24.2 0.5 2.7 2 1 1 3 3 3 2 EF-hand domain pair Flt3_lig PF02947.14 EKX42911.1 - 0.017 15.3 0.8 0.16 12.2 0.0 2.4 2 1 0 3 3 3 0 flt3 ligand B5 PF03484.15 EKX42911.1 - 0.091 13.1 0.0 0.33 11.3 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetase B5 domain Cep57_CLD_2 PF14197.6 EKX42911.1 - 2.2 8.4 8.1 0.79 9.9 3.2 2.6 2 1 2 4 4 4 0 Centrosome localisation domain of PPC89 Ank_2 PF12796.7 EKX42912.1 - 6.5e-23 81.1 3.9 8e-16 58.4 1.6 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX42912.1 - 1.5e-16 60.5 2.7 9.2e-07 29.3 0.3 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX42912.1 - 2.3e-16 59.6 2.7 3.1e-06 27.3 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX42912.1 - 2.3e-15 55.2 1.1 0.0015 18.8 0.1 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 EKX42912.1 - 2.4e-15 56.2 6.2 0.0003 21.1 0.9 5.1 5 0 0 5 5 5 4 Ankyrin repeat Tropomyosin PF00261.20 EKX42913.1 - 0.01 15.3 0.9 0.017 14.5 0.9 1.3 1 0 0 1 1 1 1 Tropomyosin NPV_P10 PF05531.12 EKX42913.1 - 0.014 15.8 0.7 0.033 14.6 0.7 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein TRPM_tetra PF16519.5 EKX42913.1 - 0.014 15.4 2.9 0.023 14.8 0.8 2.3 1 1 1 2 2 2 0 Tetramerisation domain of TRPM Phasin PF05597.11 EKX42913.1 - 0.057 13.4 0.4 0.12 12.4 0.4 1.4 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) AFOR_N PF02730.15 EKX42913.1 - 0.061 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain DUF1664 PF07889.12 EKX42913.1 - 0.79 9.8 5.4 0.13 12.3 1.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 EKX42913.1 - 2.5 8.4 4.7 0.39 11.0 0.5 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 EKX42913.1 - 2.5 8.1 6.0 0.22 11.5 1.4 1.5 2 0 0 2 2 2 0 Laminin Domain II Lzipper-MIP1 PF14389.6 EKX42914.1 - 0.036 14.4 2.1 0.036 14.4 2.1 3.5 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF3947 PF13135.6 EKX42914.1 - 0.082 13.1 0.2 0.082 13.1 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3947) APH PF01636.23 EKX42914.1 - 0.41 10.5 4.9 0.71 9.7 4.9 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FUSC PF04632.12 EKX42914.1 - 5.6 5.4 15.0 8.4 4.8 15.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family AIP3 PF03915.13 EKX42914.1 - 6.5 5.7 23.3 0.059 12.4 14.2 1.8 2 0 0 2 2 2 0 Actin interacting protein 3 AIP3 PF03915.13 EKX42915.1 - 0.047 12.8 15.6 0.071 12.2 15.6 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 HOOK PF05622.12 EKX42915.1 - 0.12 10.6 24.2 0.16 10.1 24.2 1.1 1 0 0 1 1 1 0 HOOK protein MscS_porin PF12795.7 EKX42915.1 - 0.2 11.2 33.7 0.31 10.6 33.7 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain GREB1 PF15782.5 EKX42915.1 - 0.49 7.5 5.2 0.63 7.1 5.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Lzipper-MIP1 PF14389.6 EKX42915.1 - 0.72 10.2 24.5 0.081 13.2 2.7 3.5 1 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Goodbye PF17109.5 EKX42915.1 - 2.5 8.6 6.3 4.5 7.7 2.2 2.9 2 1 1 3 3 3 0 fungal STAND N-terminal Goodbye domain AAA_13 PF13166.6 EKX42915.1 - 4 6.0 12.5 5.7 5.4 12.5 1.1 1 0 0 1 1 1 0 AAA domain FUSC PF04632.12 EKX42915.1 - 5.7 5.3 13.6 10 4.5 13.6 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family SKA1 PF07160.12 EKX42915.1 - 8.8 6.1 17.4 0.19 11.5 4.8 2.6 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 AIP3 PF03915.13 EKX42916.1 - 0.0002 20.6 2.3 0.0003 20.0 2.3 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 EzrA PF06160.12 EKX42916.1 - 0.059 11.6 3.2 0.085 11.0 3.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA GAS PF13851.6 EKX42916.1 - 0.16 11.3 10.7 0.32 10.3 10.7 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Macoilin PF09726.9 EKX42916.1 - 0.2 10.2 5.1 0.34 9.4 5.1 1.3 1 0 0 1 1 1 0 Macoilin family Fez1 PF06818.15 EKX42916.1 - 0.22 11.9 9.8 0.47 10.9 9.8 1.5 1 0 0 1 1 1 0 Fez1 Lzipper-MIP1 PF14389.6 EKX42916.1 - 0.23 11.8 10.7 0.12 12.7 2.6 2.5 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Atg14 PF10186.9 EKX42916.1 - 0.36 9.9 10.0 0.66 9.0 10.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Golgin_A5 PF09787.9 EKX42916.1 - 0.41 10.1 10.8 0.81 9.1 10.8 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 SseC PF04888.12 EKX42916.1 - 0.68 9.5 10.7 1.3 8.6 10.7 1.4 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Goodbye PF17109.5 EKX42916.1 - 0.8 10.2 2.5 4.4 7.8 1.6 2.3 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain SKA1 PF07160.12 EKX42916.1 - 0.99 9.2 8.8 0.4 10.5 5.1 1.9 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Spc7 PF08317.11 EKX42916.1 - 2.9 6.7 11.5 4.5 6.1 11.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein HOOK PF05622.12 EKX42916.1 - 3.3 5.8 14.5 4.6 5.3 14.5 1.1 1 0 0 1 1 1 0 HOOK protein Uso1_p115_C PF04871.13 EKX42916.1 - 3.9 7.9 13.8 12 6.3 13.8 1.9 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Tho2 PF11262.8 EKX42916.1 - 4.4 6.4 4.9 7.8 5.6 4.9 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF1151 PF06625.11 EKX42916.1 - 5.8 6.9 9.5 8.5 6.4 8.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1151) Med9 PF07544.13 EKX42916.1 - 6.1 7.0 9.0 9.4 6.4 1.3 2.5 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TMPIT PF07851.13 EKX42916.1 - 8.6 5.5 5.9 13 4.9 5.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein THOC7 PF05615.13 EKX42916.1 - 8.8 6.6 17.9 0.48 10.7 5.2 3.1 2 1 1 3 3 3 0 Tho complex subunit 7 Aha1_N PF09229.11 EKX42918.1 - 1.8e-07 31.5 0.1 3.5e-07 30.5 0.1 1.5 1 1 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal CDC37_N PF03234.14 EKX42918.1 - 0.00045 21.1 1.9 0.0046 17.9 0.3 2.3 2 0 0 2 2 2 1 Cdc37 N terminal kinase binding PP2C PF00481.21 EKX42919.1 - 8.2e-38 130.5 0.0 1.2e-37 130.0 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C AIP3 PF03915.13 EKX42920.1 - 0.0038 16.4 38.4 0.11 11.5 14.8 2.2 2 0 0 2 2 2 2 Actin interacting protein 3 XPB_DRD PF18458.1 EKX42920.1 - 0.01 15.7 2.9 4 7.4 0.2 2.9 2 0 0 2 2 2 0 Xeroderma pigmentosum group B helicase damage recognition domain HOOK PF05622.12 EKX42920.1 - 0.083 11.0 56.5 0.44 8.6 24.0 2.1 2 0 0 2 2 2 0 HOOK protein Lzipper-MIP1 PF14389.6 EKX42920.1 - 0.5 10.7 52.5 0.18 12.1 2.6 6.4 4 2 2 6 6 6 0 Leucine-zipper of ternary complex factor MIP1 SseC PF04888.12 EKX42920.1 - 0.51 9.9 23.4 1 8.9 6.5 2.5 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family MscS_porin PF12795.7 EKX42920.1 - 0.52 9.8 77.7 2.2 7.8 34.9 2.3 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain EF-G-binding_N PF07299.11 EKX42920.1 - 0.62 10.6 7.7 11 6.7 0.9 2.8 2 2 0 2 2 2 0 Elongation factor G-binding protein, N-terminal Ribosomal_L17 PF01196.19 EKX42920.1 - 0.66 10.9 13.2 8.2 7.4 2.8 3.0 2 0 0 2 2 2 0 Ribosomal protein L17 NICE-3 PF07406.11 EKX42920.1 - 0.73 9.8 13.2 4 7.4 2.8 2.4 2 0 0 2 2 2 0 NICE-3 protein NDUFV3 PF15880.5 EKX42920.1 - 1.9 8.6 3.4 43 4.2 0.3 2.7 2 0 0 2 2 2 0 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial SMC_ScpB PF04079.16 EKX42920.1 - 1.9 8.1 15.4 3.8 7.1 2.8 2.9 3 0 0 3 3 3 0 Segregation and condensation complex subunit ScpB Myosin_tail_1 PF01576.19 EKX42920.1 - 3.1 5.5 59.2 1.9 6.2 25.2 2.1 2 0 0 2 2 2 0 Myosin tail Goodbye PF17109.5 EKX42920.1 - 3.2 8.2 17.0 8.9 6.8 2.0 4.6 4 2 0 4 4 4 0 fungal STAND N-terminal Goodbye domain GREB1 PF15782.5 EKX42920.1 - 4.3 4.3 18.8 2.1 5.3 5.2 2.0 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer Fez1 PF06818.15 EKX42920.1 - 4.7 7.6 47.2 1.9 8.9 17.0 2.9 2 0 0 2 2 2 0 Fez1 Phage_TAC_3 PF06896.11 EKX42920.1 - 8.6 7.0 10.1 25 5.5 1.6 2.9 2 0 0 2 2 2 0 Phage tail assembly chaperone proteins, TAC AIP3 PF03915.13 EKX42921.1 - 0.039 13.1 14.7 0.058 12.5 14.7 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 Lzipper-MIP1 PF14389.6 EKX42921.1 - 0.21 11.9 22.7 0.06 13.6 2.2 3.4 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 HOOK PF05622.12 EKX42921.1 - 0.28 9.3 22.9 0.39 8.8 22.9 1.1 1 0 0 1 1 1 0 HOOK protein MscS_porin PF12795.7 EKX42921.1 - 0.28 10.7 33.1 0.44 10.0 33.1 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain GREB1 PF15782.5 EKX42921.1 - 0.52 7.4 4.7 0.67 7.0 4.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Goodbye PF17109.5 EKX42921.1 - 2.4 8.6 5.9 2.2 8.7 1.4 2.8 3 0 0 3 3 3 0 fungal STAND N-terminal Goodbye domain Fib_alpha PF08702.10 EKX42921.1 - 4.2 7.5 11.2 5.2 7.2 3.7 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family AIP3 PF03915.13 EKX42922.1 - 0.038 13.1 14.6 0.055 12.6 14.6 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 MscS_porin PF12795.7 EKX42922.1 - 0.2 11.1 32.0 0.32 10.5 32.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Lzipper-MIP1 PF14389.6 EKX42922.1 - 0.21 11.9 22.6 0.06 13.6 2.2 3.4 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 HOOK PF05622.12 EKX42922.1 - 0.39 8.8 22.7 0.55 8.3 22.7 1.1 1 0 0 1 1 1 0 HOOK protein GREB1 PF15782.5 EKX42922.1 - 0.59 7.2 4.5 0.75 6.8 4.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Fib_alpha PF08702.10 EKX42922.1 - 4.2 7.5 11.1 5.2 7.2 3.7 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family FUSC PF04632.12 EKX42922.1 - 9.4 4.6 13.0 18 3.7 13.0 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ank_4 PF13637.6 EKX42923.1 - 1.3e-56 188.3 5.1 1.5e-10 41.4 0.1 7.7 5 1 3 8 8 8 8 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX42923.1 - 2.6e-50 169.0 10.2 9.5e-11 42.1 0.1 5.8 1 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX42923.1 - 1.1e-29 99.2 2.3 0.89 10.3 0.0 11.9 12 0 0 12 12 12 9 Ankyrin repeat Ank PF00023.30 EKX42923.1 - 5.1e-21 74.1 6.7 0.054 14.0 0.0 11.6 12 0 0 12 12 12 6 Ankyrin repeat Ank_5 PF13857.6 EKX42923.1 - 1.7e-20 72.8 5.1 0.76 10.2 0.0 11.8 8 2 4 12 12 12 5 Ankyrin repeats (many copies) DUF5314 PF17241.2 EKX42923.1 - 0.0012 18.6 2.4 62 3.2 0.0 6.7 5 3 5 10 10 10 0 Family of unknown function (DUF5314) Ins_beta PF03488.14 EKX42923.1 - 0.0015 18.5 15.4 23 5.1 0.2 7.7 7 1 1 8 8 8 0 Nematode insulin-related peptide beta type Mo-nitro_C PF06967.11 EKX42923.1 - 0.039 13.9 5.0 67 3.6 0.0 6.3 9 0 0 9 9 9 0 Mo-dependent nitrogenase C-terminus Herpes_UL33 PF03581.13 EKX42923.1 - 0.044 14.1 11.3 0.72 10.3 0.0 6.1 2 2 3 5 5 5 0 Herpesvirus UL33-like protein FAF PF11250.8 EKX42923.1 - 0.074 13.3 0.5 17 5.8 0.0 4.4 4 2 1 5 5 5 0 Fantastic Four meristem regulator Rogdi_lz PF10259.9 EKX42924.1 - 0.04 13.4 0.1 0.049 13.1 0.1 1.2 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein PspA_IM30 PF04012.12 EKX42924.1 - 0.1 12.2 11.3 0.14 11.7 11.3 1.1 1 0 0 1 1 1 0 PspA/IM30 family Jnk-SapK_ap_N PF09744.9 EKX42924.1 - 0.38 11.0 9.4 0.54 10.5 9.4 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 THOC7 PF05615.13 EKX42924.1 - 1 9.6 9.1 10 6.4 9.2 2.0 1 1 0 1 1 1 0 Tho complex subunit 7 CorA PF01544.18 EKX42924.1 - 1.5 8.1 5.4 2.1 7.6 5.4 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Cnn_1N PF07989.11 EKX42924.1 - 1.6 8.9 8.0 0.95 9.7 3.9 2.3 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 GldM_N PF12081.8 EKX42925.1 - 1.8 8.6 19.1 7.8 6.5 8.5 2.5 1 1 1 2 2 2 0 GldM N-terminal domain GldM_N PF12081.8 EKX42926.1 - 1.9 8.6 19.1 7.8 6.5 8.5 2.5 1 1 1 2 2 2 0 GldM N-terminal domain tRNA_deacylase PF04414.12 EKX42927.1 - 5.7e-49 166.4 0.1 9.4e-26 90.6 0.0 2.1 2 0 0 2 2 2 2 D-aminoacyl-tRNA deacylase TTL PF03133.15 EKX42930.1 - 1.4e-79 267.3 0.0 1.8e-79 267.0 0.0 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EKX42930.1 - 1e-09 38.1 0.0 2.2e-05 23.8 0.0 3.2 2 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EKX42930.1 - 0.00019 20.8 0.0 0.036 13.3 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EKX42930.1 - 0.0068 16.5 0.0 0.21 11.6 0.0 2.6 3 0 0 3 3 3 1 ATP-grasp domain RimK PF08443.11 EKX42930.1 - 0.086 12.4 0.0 3.6 7.1 0.0 2.2 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Cupin_8 PF13621.6 EKX42932.1 - 4.7e-24 85.5 0.0 8.9e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EKX42932.1 - 4.2e-11 42.9 0.1 5.8e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 EKX42932.1 - 8.2e-05 23.0 0.0 0.00029 21.2 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EKX42932.1 - 0.064 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Myb_DNA-binding PF00249.31 EKX42934.1 - 7.3e-08 32.5 0.4 2.1e-07 31.0 0.4 1.8 1 1 0 1 1 1 1 Myb-like DNA-binding domain TEA PF01285.18 EKX42934.1 - 0.017 15.2 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 TEA/ATTS domain Ion_trans_2 PF07885.16 EKX42936.1 - 2.9e-09 36.8 0.9 2.9e-09 36.8 0.9 2.7 3 0 0 3 3 3 1 Ion channel Ion_trans PF00520.31 EKX42936.1 - 0.004 16.4 13.9 0.22 10.7 6.5 2.1 1 1 1 2 2 2 2 Ion transport protein EF-hand_6 PF13405.6 EKX42937.1 - 3.6e-12 45.2 6.9 0.0049 16.7 0.0 5.6 5 0 0 5 5 5 3 EF-hand domain EF-hand_1 PF00036.32 EKX42937.1 - 3.6e-11 41.8 5.0 0.00084 18.7 0.0 5.0 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 EKX42937.1 - 5.8e-09 36.3 18.2 0.0012 19.3 0.1 5.5 5 1 0 5 5 5 3 EF-hand domain pair EF-hand_8 PF13833.6 EKX42937.1 - 3.8e-07 29.9 12.7 0.0016 18.3 1.0 5.2 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 EKX42937.1 - 0.076 12.5 5.3 0.23 11.0 0.0 3.8 4 0 0 4 4 4 0 EF hand Cyclin_N PF00134.23 EKX42938.1 - 1.3e-30 105.8 2.0 2.1e-30 105.1 0.3 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EKX42938.1 - 4.7e-19 68.6 0.4 1.1e-18 67.4 0.1 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain F-box PF00646.33 EKX42938.1 - 1.3e-06 28.1 0.1 2.5e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 F-box domain IreB PF06135.12 EKX42938.1 - 0.0036 17.5 0.0 0.0093 16.1 0.0 1.7 1 0 0 1 1 1 1 IreB regulatory phosphoprotein F-box-like PF12937.7 EKX42938.1 - 0.015 15.2 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 F-box-like CSF-1 PF05337.11 EKX42938.1 - 0.12 12.5 0.2 3.7 7.6 0.0 2.7 3 0 0 3 3 3 0 Macrophage colony stimulating factor-1 (CSF-1) Leu_Phe_trans PF03588.14 EKX42939.1 - 4.4e-27 94.7 0.0 5.8e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Leucyl/phenylalanyl-tRNA protein transferase CUE PF02845.16 EKX42939.1 - 5.5e-07 29.2 0.1 4.6e-06 26.2 0.0 2.4 2 0 0 2 2 2 1 CUE domain Acetyltransf_6 PF13480.7 EKX42939.1 - 0.057 13.6 0.1 0.2 11.8 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain 2_5_RNA_ligase2 PF13563.6 EKX42941.1 - 1e-21 77.5 0.3 8.8e-21 74.4 0.3 2.3 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily KLRAQ PF10205.9 EKX42941.1 - 0.46 10.8 4.7 3.4 8.0 1.7 2.9 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein WD40 PF00400.32 EKX42942.1 - 3.5e-14 52.9 7.0 0.0012 19.7 0.1 6.8 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX42942.1 - 5.6e-10 39.4 0.4 0.21 11.9 0.0 6.2 4 2 1 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain DUF884 PF05959.11 EKX42943.1 - 0.041 13.5 0.2 0.065 12.9 0.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF884) PAE PF03283.13 EKX42944.1 - 1.2e-23 83.8 0.3 1.3e-22 80.4 0.3 1.9 1 1 0 1 1 1 1 Pectinacetylesterase Peptidase_C27 PF05407.12 EKX42944.1 - 0.28 11.2 1.1 5.2 7.1 0.1 2.1 1 1 0 2 2 2 0 Rubella virus endopeptidase PRORP PF16953.5 EKX42945.1 - 2.2e-22 79.8 1.7 2.2e-22 79.8 1.7 2.3 3 0 0 3 3 3 1 Protein-only RNase P PPR_long PF17177.4 EKX42945.1 - 1.5e-18 66.9 5.3 3.8e-18 65.6 5.3 1.6 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP RNase_Zc3h12a PF11977.8 EKX42945.1 - 3.5e-09 36.6 0.0 8.6e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PPR PF01535.20 EKX42945.1 - 0.00015 21.8 6.5 1.8 9.0 0.1 5.5 6 0 0 6 6 6 2 PPR repeat PPR_3 PF13812.6 EKX42945.1 - 0.00022 21.2 3.4 0.24 11.5 0.1 4.0 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 EKX42945.1 - 0.032 14.4 9.2 0.31 11.3 0.5 5.0 5 0 0 5 5 5 0 PPR repeat family ANAPC4 PF12896.7 EKX42945.1 - 0.089 12.3 4.3 2 7.9 0.0 3.1 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 4 DUF3137 PF11335.8 EKX42945.1 - 0.12 12.4 5.4 0.83 9.6 0.6 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3137) DHDPS PF00701.22 EKX42945.1 - 0.21 10.3 0.0 0.39 9.4 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family HTH_Tnp_Tc5 PF03221.16 EKX42946.1 - 3.6e-08 33.3 0.3 7.2e-08 32.4 0.3 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CHASE5 PF17149.4 EKX42946.1 - 0.17 11.8 0.0 0.46 10.4 0.0 1.7 1 0 0 1 1 1 0 Periplasmic sensor domain found in signal transduction proteins Unstab_antitox PF09720.10 EKX42946.1 - 3 8.0 10.6 0.63 10.1 0.5 3.5 2 1 1 3 3 3 0 Putative addiction module component eIF2A PF08662.11 EKX42947.1 - 2.1e-60 204.0 4.6 1.1e-54 185.2 0.0 4.1 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 EKX42947.1 - 2.8e-08 34.0 0.1 0.073 13.4 0.0 5.1 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 EKX42947.1 - 1.1e-07 31.5 1.0 3.8e-07 29.8 0.1 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IKI3 PF04762.12 EKX42947.1 - 9.4e-05 20.6 0.0 0.17 9.8 0.0 2.8 1 1 2 3 3 3 2 IKI3 family RRM_2 PF04059.12 EKX42947.1 - 0.0012 19.1 0.1 0.0037 17.4 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif 2 PurA PF04845.13 EKX42947.1 - 0.054 12.8 0.1 0.099 12.0 0.1 1.3 1 0 0 1 1 1 0 PurA ssDNA and RNA-binding protein WD40 PF00400.32 EKX42947.1 - 0.77 10.7 5.2 3.4e+02 2.4 0.0 5.9 8 0 0 8 8 8 0 WD domain, G-beta repeat M16C_assoc PF08367.11 EKX42947.1 - 3.1 6.8 5.5 4.7 6.3 5.5 1.2 1 0 0 1 1 1 0 Peptidase M16C associated WD40 PF00400.32 EKX42950.1 - 0.0001 23.0 0.4 0.1 13.5 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat NAPRTase_C PF17956.1 EKX42953.1 - 0.061 13.8 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase C-terminal domain MRP-S27 PF10037.9 EKX42953.1 - 0.077 11.9 0.7 0.35 9.7 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 Anth_synt_I_N PF04715.13 EKX42953.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region Snapin_Pallidin PF14712.6 EKX42953.1 - 0.24 11.9 5.1 2.9 8.4 0.8 2.4 2 0 0 2 2 2 0 Snapin/Pallidin DUF4706 PF15797.5 EKX42953.1 - 0.37 11.3 4.0 0.69 10.5 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4706) DUF4709 PF15821.5 EKX42953.1 - 0.9 9.8 3.8 2.4 8.5 1.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4709) Big_9 PF17963.1 EKX42955.1 - 0.0018 19.0 13.7 2.3 9.0 0.5 6.9 7 0 0 7 7 7 2 Bacterial Ig domain Zn_clus PF00172.18 EKX42956.1 - 3.4e-09 36.7 39.6 3.1e-06 27.2 12.2 2.8 2 1 1 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Gon7 PF08738.10 EKX42957.1 - 9.4e-05 22.5 0.2 0.00012 22.1 0.2 1.2 1 0 0 1 1 1 1 Gon7 family DUF4611 PF15387.6 EKX42957.1 - 0.25 11.6 4.8 0.55 10.5 4.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) HBM PF16591.5 EKX42958.1 - 1.5e-05 24.6 8.1 2e-05 24.2 8.1 1.1 1 0 0 1 1 1 1 Helical bimodular sensor domain DUF2353 PF09789.9 EKX42958.1 - 0.004 16.6 5.8 0.0054 16.1 5.8 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) WEMBL PF05701.11 EKX42958.1 - 0.02 13.6 6.0 0.012 14.4 3.9 1.4 1 1 0 1 1 1 0 Weak chloroplast movement under blue light HeLo PF14479.6 EKX42958.1 - 0.024 14.5 3.3 0.035 13.9 3.3 1.2 1 0 0 1 1 1 0 Prion-inhibition and propagation Cep57_CLD_2 PF14197.6 EKX42958.1 - 0.04 14.0 7.0 0.09 12.9 4.3 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 ABC_tran_CTD PF16326.5 EKX42958.1 - 0.063 13.5 1.6 0.063 13.5 1.6 2.6 2 1 0 2 2 2 0 ABC transporter C-terminal domain Gp58 PF07902.11 EKX42958.1 - 0.11 10.7 4.4 0.15 10.3 4.4 1.0 1 0 0 1 1 1 0 gp58-like protein Prominin PF05478.11 EKX42958.1 - 0.12 10.3 0.3 0.14 10.1 0.3 1.0 1 0 0 1 1 1 0 Prominin ERM PF00769.19 EKX42958.1 - 0.25 11.1 10.2 0.38 10.5 10.2 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF4200 PF13863.6 EKX42958.1 - 0.36 11.3 8.9 0.55 10.6 8.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Exonuc_VII_L PF02601.15 EKX42958.1 - 0.37 10.3 5.3 0.51 9.9 5.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2570 PF10828.8 EKX42958.1 - 0.38 10.6 9.8 2.3 8.1 4.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) Lebercilin PF15619.6 EKX42958.1 - 0.41 10.3 13.6 0.23 11.1 2.6 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF4407 PF14362.6 EKX42958.1 - 0.71 9.2 6.4 1.2 8.4 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATP-synt_B PF00430.18 EKX42958.1 - 0.72 9.9 9.1 1.8 8.7 8.9 1.7 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) KELK PF15796.5 EKX42958.1 - 1.1 9.8 9.5 2.1 8.8 9.5 1.5 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase RasGAP_C PF03836.15 EKX42958.1 - 1.7 8.8 9.9 4.7 7.3 1.6 2.1 1 1 1 2 2 2 0 RasGAP C-terminus Fib_alpha PF08702.10 EKX42958.1 - 1.9 8.7 4.6 3 8.0 4.6 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 EKX42958.1 - 2.3 8.9 17.3 0.91 10.2 2.8 2.8 3 1 1 4 4 2 0 SlyX TMF_DNA_bd PF12329.8 EKX42958.1 - 2.8 8.0 9.1 1.8 8.6 4.3 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Jnk-SapK_ap_N PF09744.9 EKX42958.1 - 4.7 7.4 11.5 14 5.9 11.5 1.7 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 CENP-H PF05837.12 EKX42958.1 - 5.4 7.5 11.2 9.1 6.7 1.0 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Zn_clus PF00172.18 EKX42959.1 - 7.1e-05 22.9 9.6 0.00011 22.3 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_binding_1 PF01035.20 EKX42959.1 - 0.016 15.3 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, DNA binding domain Myb_DNA-binding PF00249.31 EKX42960.1 - 0.00018 21.6 0.0 0.00059 20.0 0.0 1.9 1 1 0 1 1 1 1 Myb-like DNA-binding domain DUF4611 PF15387.6 EKX42960.1 - 0.021 15.0 4.6 0.047 13.9 4.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) FAM176 PF14851.6 EKX42960.1 - 0.063 12.9 2.0 0.12 12.0 2.0 1.4 1 0 0 1 1 1 0 FAM176 family Mis14 PF08641.12 EKX42960.1 - 0.14 12.4 2.1 0.28 11.5 2.1 1.4 1 0 0 1 1 1 0 Kinetochore protein Mis14 like Pox_Ag35 PF03286.14 EKX42960.1 - 0.21 11.3 4.6 0.49 10.2 4.6 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RXT2_N PF08595.11 EKX42960.1 - 1.1 9.3 5.0 1.8 8.5 5.0 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Rhabdo_ncap PF00945.18 EKX42960.1 - 1.3 7.9 3.8 1.9 7.3 3.8 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein CDC45 PF02724.14 EKX42960.1 - 2.1 6.5 5.3 3.2 6.0 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 EKX42960.1 - 2.2 6.3 7.1 3 5.9 7.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Myb_DNA-binding PF00249.31 EKX42961.1 - 0.00018 21.6 0.0 0.00059 20.0 0.0 1.9 1 1 0 1 1 1 1 Myb-like DNA-binding domain DUF4611 PF15387.6 EKX42961.1 - 0.023 14.9 4.0 0.051 13.8 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) FAM176 PF14851.6 EKX42961.1 - 0.1 12.2 1.6 0.2 11.3 1.6 1.4 1 0 0 1 1 1 0 FAM176 family Pox_Ag35 PF03286.14 EKX42961.1 - 0.2 11.4 3.6 0.45 10.3 3.6 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RFXA_RFXANK_bdg PF15289.6 EKX42961.1 - 0.58 10.5 3.4 0.39 11.1 0.6 2.0 2 0 0 2 2 2 0 Regulatory factor X-associated C-terminal binding domain DNA_pol_phi PF04931.13 EKX42961.1 - 2.8 5.9 6.1 3.8 5.5 6.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi UPF0061 PF02696.14 EKX42962.1 - 1.8e-75 254.5 0.0 3.2e-39 135.0 0.0 2.0 2 0 0 2 2 2 2 Uncharacterized ACR, YdiU/UPF0061 family Chlorophyllase PF07224.11 EKX42963.1 - 0.093 11.7 0.0 0.63 9.0 0.0 1.9 2 0 0 2 2 2 0 Chlorophyllase UBX PF00789.20 EKX42964.1 - 0.00043 20.4 0.0 0.001 19.2 0.0 1.6 1 0 0 1 1 1 1 UBX domain BshC PF10079.9 EKX42964.1 - 1.3 7.7 6.2 1.8 7.2 6.2 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC AMPK1_CBM PF16561.5 EKX42965.1 - 3.9e-17 62.2 0.0 5.3e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 EKX42965.1 - 0.11 12.9 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Phycoerythr_ab PF02972.14 EKX42966.1 - 2.5e-20 72.0 0.0 5.8e-20 70.9 0.0 1.6 2 0 0 2 2 2 1 Phycoerythrin, alpha/beta chain TAT_signal PF10518.9 EKX42966.1 - 0.032 14.1 2.0 0.032 14.1 2.0 2.6 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence SNF2_N PF00176.23 EKX42967.1 - 3.3e-64 216.8 0.4 3.3e-64 216.8 0.4 1.7 2 1 1 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX42967.1 - 1.7e-17 63.8 0.0 1.4e-15 57.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EKX42967.1 - 2.4e-06 27.4 0.0 4.3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EKX42967.1 - 3.4e-06 27.2 0.0 7.2e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EKX42967.1 - 7.9e-06 25.2 0.2 2.4e-05 23.7 0.2 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 EKX42967.1 - 0.0022 17.2 1.5 0.012 14.9 0.1 2.3 3 0 0 3 3 3 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 EKX42967.1 - 0.022 15.0 0.3 0.21 11.9 0.0 2.6 3 1 0 3 3 3 0 AAA domain Mito_carr PF00153.27 EKX42968.1 - 1.5e-65 217.2 5.3 5.3e-22 77.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein TetR_C_14 PF17754.1 EKX42968.1 - 0.0054 16.7 0.2 0.048 13.6 0.0 2.2 2 0 0 2 2 2 1 MftR C-terminal domain ThiF PF00899.21 EKX42969.1 - 1.6e-61 207.8 0.0 2.1e-61 207.4 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 EKX42969.1 - 3.8e-12 46.2 0.0 5.9e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 E2 binding domain UBA_e1_thiolCys PF10585.9 EKX42969.1 - 0.071 13.0 0.3 2.9 7.8 0.0 2.1 1 1 1 2 2 2 0 Ubiquitin-activating enzyme active site Pyr_redox PF00070.27 EKX42969.1 - 0.17 12.4 0.0 0.42 11.2 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Rad50_zn_hook PF04423.14 EKX42969.1 - 0.24 11.3 0.4 0.46 10.4 0.4 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif Ank_2 PF12796.7 EKX42973.1 - 4.8e-32 110.4 3.6 9.9e-15 54.9 0.2 3.5 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX42973.1 - 1.4e-21 76.6 4.1 2e-07 31.4 0.1 5.0 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EKX42973.1 - 1.2e-19 69.7 9.2 0.00045 20.5 0.1 6.0 5 1 1 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EKX42973.1 - 9.9e-19 67.2 1.7 4.6e-05 23.6 0.0 4.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX42973.1 - 3.8e-18 63.7 4.9 0.0011 19.3 0.0 6.1 7 0 0 7 7 7 4 Ankyrin repeat Ank_2 PF12796.7 EKX42974.1 - 7.5e-08 32.9 1.8 2.1e-07 31.4 1.8 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX42974.1 - 3.5e-06 27.4 2.4 0.00057 20.4 0.1 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX42974.1 - 2.6e-05 24.3 1.5 0.011 16.1 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EKX42974.1 - 0.00037 20.7 3.6 0.0076 16.6 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX42974.1 - 0.00084 19.7 2.5 0.0018 18.6 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat DUF4559 PF15112.6 EKX42974.1 - 0.14 11.8 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Bestrophin PF01062.21 EKX42977.1 - 2.7e-27 96.0 2.0 1.3e-16 60.9 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Beta-TrCP_D PF12125.8 EKX42978.1 - 0.036 14.0 0.2 2.6 8.0 0.3 2.7 2 0 0 2 2 2 0 D domain of beta-TrCP Zn_clus PF00172.18 EKX42979.1 - 3.7e-09 36.6 35.7 0.00018 21.6 14.7 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Histone PF00125.24 EKX42980.1 - 3.5e-19 69.5 0.6 4.3e-19 69.2 0.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EKX42980.1 - 0.00024 21.3 0.0 0.00045 20.5 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EKX42980.1 - 0.0015 19.0 0.0 0.0027 18.2 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 EKX42980.1 - 0.013 15.5 1.5 0.016 15.2 1.5 1.2 1 0 0 1 1 1 0 YscO-like protein CbiX PF01903.17 EKX42981.1 - 0.091 13.1 0.2 0.17 12.2 0.2 1.5 1 0 0 1 1 1 0 CbiX PRAP PF15314.6 EKX42981.1 - 0.34 11.4 3.7 0.3 11.6 1.0 2.5 2 1 0 2 2 2 0 Proline-rich acidic protein 1, pregnancy-specific uterine tRNA_Me_trans PF03054.16 EKX42984.1 - 9.6e-100 333.8 0.0 1.1e-99 333.6 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 EKX42984.1 - 8.8e-05 22.2 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) ATP_bind_3 PF01171.20 EKX42984.1 - 9.5e-05 22.2 0.1 0.026 14.3 0.1 2.1 2 0 0 2 2 2 2 PP-loop family NAD_synthase PF02540.17 EKX42984.1 - 0.00016 20.9 0.0 0.0013 17.9 0.1 2.1 2 1 0 2 2 2 1 NAD synthase QueC PF06508.13 EKX42984.1 - 0.0029 17.1 0.0 0.0053 16.3 0.0 1.5 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 EKX42984.1 - 0.003 17.3 0.0 0.0042 16.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase Polysacc_deac_1 PF01522.21 EKX42985.1 - 7.4e-11 42.0 0.0 1.8e-10 40.8 0.0 1.6 1 1 0 1 1 1 1 Polysaccharide deacetylase BBIP10 PF14777.6 EKX42985.1 - 0.13 11.8 0.1 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Cilia BBSome complex subunit 10 DUF2695 PF10905.8 EKX42985.1 - 0.15 12.3 3.9 13 6.1 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2695) DUF4203 PF13886.6 EKX42987.1 - 0.0045 16.7 14.1 0.0077 15.9 14.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) TauE PF01925.19 EKX42987.1 - 4.2 6.9 19.7 0.54 9.9 13.8 2.5 2 1 0 2 2 2 0 Sulfite exporter TauE/SafE Cnd1 PF12717.7 EKX42988.1 - 0.0031 17.6 0.7 0.0046 17.0 0.1 1.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 W2 PF02020.18 EKX42988.1 - 0.024 14.8 0.1 0.055 13.6 0.1 1.6 1 0 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon CBF PF03914.17 EKX42988.1 - 0.046 13.7 1.2 0.57 10.2 0.1 2.5 2 0 0 2 2 2 0 CBF/Mak21 family WD40 PF00400.32 EKX42990.1 - 1.1e-19 70.3 8.4 0.022 15.6 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EKX42990.1 - 0.00056 19.0 0.0 2.3 7.1 0.0 3.6 1 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2684 PF10885.8 EKX42990.1 - 0.041 14.0 0.1 0.092 12.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2684) ELYS-bb PF16687.5 EKX42990.1 - 0.048 12.3 0.0 0.11 11.0 0.0 1.6 1 1 0 1 1 1 0 beta-propeller of ELYS nucleoporin Pkinase PF00069.25 EKX42991.1 - 8.8e-07 28.5 0.1 8.3e-06 25.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 EKX42991.1 - 0.0017 17.7 0.8 0.012 14.9 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EKX42991.1 - 0.02 14.2 1.1 0.31 10.3 0.3 2.4 2 1 0 2 2 2 0 Protein tyrosine kinase APH PF01636.23 EKX42991.1 - 0.033 14.1 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 EKX42991.1 - 0.13 11.8 0.1 4.9 6.7 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Glyco_transf_41 PF13844.6 EKX42992.1 - 8.4e-50 169.6 3.6 9.7e-35 119.9 0.1 2.8 2 1 1 3 3 3 2 Glycosyl transferase family 41 TPR_1 PF00515.28 EKX42992.1 - 1.9e-07 30.6 0.0 3.9e-05 23.3 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX42992.1 - 3.3e-07 30.7 0.3 4.8e-05 23.8 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX42992.1 - 4e-06 27.2 3.9 0.0014 19.3 0.1 4.5 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX42992.1 - 4.1e-06 26.5 0.8 4.5e-05 23.2 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX42992.1 - 1.3e-05 24.8 0.0 0.073 12.8 0.0 3.1 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.6 EKX42992.1 - 9.2e-05 23.0 0.0 0.00076 20.1 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX42992.1 - 0.00014 22.0 0.0 0.055 13.9 0.0 3.9 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX42992.1 - 0.0005 20.1 0.7 0.0047 17.0 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX42992.1 - 0.0031 17.8 1.0 0.029 14.7 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX42992.1 - 0.048 13.7 0.0 0.19 11.9 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX42992.1 - 0.085 13.5 0.5 34 5.4 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 EKX42992.1 - 0.096 12.8 0.5 0.34 11.1 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF5073 PF16817.5 EKX42992.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5073) MAP7 PF05672.11 EKX42992.1 - 0.16 11.7 29.1 0.27 10.9 29.1 1.3 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family AAA_11 PF13086.6 EKX42992.1 - 1.1 9.0 9.9 1.3 8.8 8.5 1.6 2 0 0 2 2 2 0 AAA domain DNA_ligase_A_M PF01068.21 EKX42994.1 - 1.6e-43 148.8 1.3 4.1e-43 147.4 0.6 2.0 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EKX42994.1 - 1.2e-29 103.9 0.3 2.4e-29 102.8 0.3 1.6 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 EKX42994.1 - 2.5e-09 37.6 0.5 4.7e-09 36.7 0.5 1.5 1 0 0 1 1 1 1 RNA ligase BRCT PF00533.26 EKX42994.1 - 2.2e-05 24.7 0.0 0.00011 22.5 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_A_C PF04679.15 EKX42994.1 - 0.00074 20.1 1.4 0.0073 16.9 0.1 3.2 3 1 0 3 3 3 1 ATP dependent DNA ligase C terminal region BRCT_2 PF16589.5 EKX42994.1 - 0.001 19.4 0.1 0.0048 17.3 0.0 2.2 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_IV PF11411.8 EKX42994.1 - 0.004 17.3 0.2 0.0087 16.2 0.2 1.6 1 0 0 1 1 1 1 DNA ligase IV Ephrin_rec_like PF07699.13 EKX42995.1 - 3.4e-24 84.3 44.9 9.2e-07 28.5 5.9 5.2 1 1 4 5 5 5 5 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX42995.1 - 4.8e-10 39.7 28.8 0.052 14.0 0.2 6.0 2 1 0 5 5 5 5 TNFR/NGFR cysteine-rich region VSP PF03302.13 EKX42995.1 - 0.00079 18.4 29.3 0.052 12.4 10.5 2.1 1 1 1 2 2 2 2 Giardia variant-specific surface protein DUF2318 PF10080.9 EKX42995.1 - 0.13 12.4 24.4 0.27 11.4 2.9 4.0 1 1 3 4 4 4 0 Predicted membrane protein (DUF2318) WW PF00397.26 EKX42996.1 - 3.5e-09 36.6 0.8 6.4e-09 35.8 0.8 1.5 1 0 0 1 1 1 1 WW domain PDZ PF00595.24 EKX42996.1 - 1.1e-05 25.7 0.0 0.00015 22.1 0.0 2.6 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX42996.1 - 0.0033 17.7 0.0 0.0088 16.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX42996.1 - 0.0065 16.3 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 PDZ domain UPF0061 PF02696.14 EKX42997.1 - 5.8e-81 272.6 0.0 3.9e-80 269.9 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family FYVE_2 PF02318.16 EKX42998.1 - 0.00066 19.9 2.7 0.00066 19.9 2.7 2.0 2 0 0 2 2 2 1 FYVE-type zinc finger zf-C2H2_4 PF13894.6 EKX42998.1 - 0.037 14.9 8.4 1.3 10.0 1.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EKX42998.1 - 0.041 14.3 0.4 0.041 14.3 0.4 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-piccolo PF05715.13 EKX42998.1 - 0.053 13.7 7.0 0.096 12.8 7.0 1.4 1 0 0 1 1 1 0 Piccolo Zn-finger SAND PF01342.21 EKX42998.1 - 0.11 12.2 5.0 0.047 13.4 2.6 1.7 2 0 0 2 2 2 0 SAND domain zf-BED PF02892.15 EKX42998.1 - 0.16 12.0 8.4 0.2 11.7 6.6 2.0 1 1 1 2 2 2 0 BED zinc finger NOB1_Zn_bind PF08772.11 EKX42998.1 - 9.2 6.5 11.2 79 3.5 10.6 2.2 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like ER_lumen_recept PF00810.18 EKX42999.1 - 4.5e-35 121.6 8.8 4.5e-35 121.6 8.8 2.3 2 1 1 3 3 3 1 ER lumen protein retaining receptor NPCC PF08058.11 EKX42999.1 - 5.2 7.1 6.3 1.7 8.7 0.2 2.5 1 1 1 2 2 2 0 Nuclear pore complex component PQ-loop PF04193.14 EKX42999.1 - 9.9 6.0 12.7 2.1 8.2 1.4 3.8 4 1 0 4 4 4 0 PQ loop repeat ubiquitin PF00240.23 EKX43000.1 - 1.3e-11 44.1 0.0 2.7e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Big_5 PF13205.6 EKX43000.1 - 5.4e-07 30.3 2.9 0.00078 20.1 0.0 3.6 3 2 0 3 3 3 2 Bacterial Ig-like domain Rad60-SLD PF11976.8 EKX43000.1 - 0.011 15.6 0.0 0.039 13.8 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EKX43000.1 - 0.17 12.0 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF3540 PF12059.8 EKX43000.1 - 0.4 10.5 28.8 5.5 6.8 9.3 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3540) WD40 PF00400.32 EKX43001.1 - 1.1e-104 339.3 51.3 1.5e-09 38.3 0.4 14.6 15 0 0 15 15 15 14 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX43001.1 - 6.6e-56 186.6 29.9 2.8e-06 27.5 0.0 13.4 1 1 10 12 12 12 12 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EKX43001.1 - 9.3e-11 42.0 0.1 0.0098 15.8 0.1 4.2 1 1 3 5 5 5 5 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EKX43001.1 - 4.2e-10 38.9 29.1 0.0098 14.6 0.2 10.2 6 2 2 10 10 10 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EKX43001.1 - 1.4e-09 37.3 12.6 1.3 7.9 0.1 9.7 1 1 6 9 9 9 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EKX43001.1 - 3.2e-07 30.1 0.1 18 5.4 0.0 8.4 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.11 EKX43001.1 - 1.5e-05 24.0 2.8 3 6.5 0.0 5.6 4 3 0 5 5 5 2 Nup133 N terminal like IKI3 PF04762.12 EKX43001.1 - 2.7e-05 22.4 19.9 0.026 12.5 7.6 3.9 2 2 1 3 3 3 3 IKI3 family Coatomer_WDAD PF04053.14 EKX43001.1 - 6.6e-05 22.1 3.9 1.8 7.5 0.0 5.0 3 2 2 5 5 5 2 Coatomer WD associated region DUF1513 PF07433.11 EKX43001.1 - 0.00025 20.2 11.9 0.06 12.4 0.0 5.5 2 2 4 6 6 6 2 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.16 EKX43001.1 - 0.0011 17.5 1.8 0.056 12.0 0.1 3.0 3 1 0 3 3 3 1 Cytochrome D1 heme domain DUF5122 PF17164.4 EKX43001.1 - 0.0066 16.7 1.5 72 3.8 0.1 5.7 7 0 0 7 7 7 0 Domain of unknown function (DUF5122) beta-propeller WD40_like PF17005.5 EKX43001.1 - 0.03 13.6 0.0 70 2.6 0.0 4.8 4 3 2 7 7 7 0 WD40-like domain Peptidase_S9_N PF02897.15 EKX43001.1 - 0.23 10.2 8.1 2.7 6.7 0.2 4.2 3 2 1 4 4 4 0 Prolyl oligopeptidase, N-terminal beta-propeller domain CHB_HEX_C_1 PF13290.6 EKX43002.1 - 4.6e-06 26.5 0.0 9.2e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 EKX43002.1 - 1.5e-05 25.0 0.0 3.2e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Fn3 associated WW PF00397.26 EKX43002.1 - 0.00012 22.1 4.5 0.00012 22.1 4.5 2.9 3 0 0 3 3 3 1 WW domain SAM_2 PF07647.17 EKX43002.1 - 0.006 16.7 0.0 0.03 14.4 0.0 2.4 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EKX43002.1 - 0.0086 16.5 0.1 0.048 14.1 0.0 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Pox_Ag35 PF03286.14 EKX43002.1 - 0.052 13.4 12.2 0.24 11.2 12.2 2.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RNA_pol_3_Rpc31 PF11705.8 EKX43002.1 - 0.5 10.6 20.2 2.4 8.4 20.2 2.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Zip PF02535.22 EKX43002.1 - 1.3 8.2 3.5 22 4.1 3.2 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter RPA43_OB PF17875.1 EKX43002.1 - 2.1 9.0 7.8 8.1 7.1 7.8 2.0 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I VAD1-2 PF15310.6 EKX43002.1 - 2.6 7.8 8.3 10 5.9 8.3 2.0 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling Connexin PF00029.19 EKX43002.1 - 3.3 7.4 6.7 8.6 6.0 6.7 1.6 1 0 0 1 1 1 0 Connexin Afi1 PF07792.12 EKX43002.1 - 4 7.9 7.5 19 5.7 7.5 2.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Presenilin PF01080.17 EKX43002.1 - 4.1 6.1 6.1 8.8 5.0 6.1 1.5 1 0 0 1 1 1 0 Presenilin RPN2_C PF18004.1 EKX43002.1 - 4.4 7.2 16.2 13 5.7 16.2 1.7 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain NOA36 PF06524.12 EKX43002.1 - 5 6.4 17.2 14 4.9 17.2 1.7 1 0 0 1 1 1 0 NOA36 protein DAP PF15228.6 EKX43002.1 - 5.5 8.2 8.5 9.9 7.4 6.4 2.6 2 0 0 2 2 1 0 Death-associated protein Response_reg PF00072.24 EKX43003.1 - 3.2e-17 62.7 0.1 3.6e-17 62.5 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain MU2_FHA PF18221.1 EKX43003.1 - 0.095 12.7 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Mutator 2 Fork head associated domain HATPase_c PF02518.26 EKX43004.1 - 7.4e-29 100.5 0.3 2.2e-28 99.0 0.1 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EKX43004.1 - 7e-15 54.8 0.1 1.3e-14 54.0 0.1 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 EKX43005.1 - 1e-14 55.3 0.0 1.2e-14 55.1 0.0 1.1 1 0 0 1 1 1 1 GAF domain NUDE_C PF04880.13 EKX43006.1 - 0.0002 21.9 2.9 0.0002 21.9 2.9 2.9 1 1 2 3 3 2 1 NUDE protein, C-terminal conserved region GAS PF13851.6 EKX43006.1 - 0.0068 15.8 12.0 0.0068 15.8 12.0 2.2 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding T4SS PF07996.11 EKX43006.1 - 0.0075 16.7 13.2 0.39 11.1 7.8 2.1 1 1 1 2 2 2 2 Type IV secretion system proteins ZapB PF06005.12 EKX43006.1 - 0.0083 16.5 37.7 0.078 13.4 16.0 3.9 1 1 2 3 3 2 2 Cell division protein ZapB ADIP PF11559.8 EKX43006.1 - 0.017 15.2 31.6 0.022 14.9 10.6 2.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding GIT_CC PF16559.5 EKX43006.1 - 0.03 14.2 13.6 0.22 11.4 1.8 3.8 1 1 3 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Cep57_CLD_2 PF14197.6 EKX43006.1 - 0.036 14.1 2.9 0.036 14.1 2.9 5.0 2 2 0 2 2 1 0 Centrosome localisation domain of PPC89 Lectin_N PF03954.14 EKX43006.1 - 0.059 13.1 14.5 0.45 10.3 1.2 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain YojJ PF10372.9 EKX43006.1 - 0.061 13.4 0.5 0.061 13.4 0.5 3.1 2 1 1 3 3 3 0 Bacterial membrane-spanning protein N-terminus Taxilin PF09728.9 EKX43006.1 - 0.13 11.5 35.6 2.8 7.1 34.6 2.0 1 1 0 1 1 1 0 Myosin-like coiled-coil protein PRKG1_interact PF15898.5 EKX43006.1 - 0.23 12.4 30.9 0.59 11.1 17.4 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain YjbH PF06082.11 EKX43006.1 - 0.25 10.1 4.8 0.29 9.9 4.8 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH CEP63 PF17045.5 EKX43006.1 - 0.31 10.9 30.6 1.6 8.6 17.2 3.0 1 1 2 3 3 3 0 Centrosomal protein of 63 kDa HMMR_N PF15905.5 EKX43006.1 - 0.35 10.3 34.0 0.086 12.3 26.5 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal YabA PF06156.13 EKX43006.1 - 0.37 11.4 26.5 0.09 13.4 3.9 3.4 1 1 2 3 3 3 0 Initiation control protein YabA SHE3 PF17078.5 EKX43006.1 - 0.5 10.1 29.3 0.39 10.4 7.3 3.4 1 1 1 3 3 3 0 SWI5-dependent HO expression protein 3 Styelin PF17562.2 EKX43006.1 - 0.56 10.6 6.7 0.16 12.4 3.2 2.0 2 0 0 2 2 1 0 Styelin Golgin_A5 PF09787.9 EKX43006.1 - 0.65 9.4 24.6 0.89 9.0 24.6 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 FlxA PF14282.6 EKX43006.1 - 0.8 9.7 21.5 0.089 12.8 2.5 2.7 1 1 1 2 2 2 0 FlxA-like protein HALZ PF02183.18 EKX43006.1 - 0.87 9.9 20.7 0.43 10.8 1.7 4.7 4 2 1 5 5 5 0 Homeobox associated leucine zipper Ant_C PF05586.11 EKX43006.1 - 1.4 9.6 6.2 2.6 8.7 2.1 2.5 1 1 1 2 2 2 0 Anthrax receptor C-terminus region DUF4618 PF15397.6 EKX43006.1 - 1.5 8.2 25.2 9.7 5.5 25.2 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) UPF0231 PF06062.11 EKX43006.1 - 2 8.7 11.0 0.41 10.9 3.0 2.8 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0231) DUF3450 PF11932.8 EKX43006.1 - 2.4 7.4 23.7 4.8 6.4 12.7 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) THOC7 PF05615.13 EKX43006.1 - 2.4 8.4 28.4 0.34 11.2 7.0 2.4 1 1 1 2 2 2 0 Tho complex subunit 7 SATase_N PF06426.14 EKX43006.1 - 2.4 8.6 6.8 0.61 10.5 1.6 2.1 2 0 0 2 2 2 0 Serine acetyltransferase, N-terminal DUF3584 PF12128.8 EKX43006.1 - 2.5 5.5 25.6 3.6 5.0 25.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DivIC PF04977.15 EKX43006.1 - 2.8 7.8 31.3 0.24 11.2 0.7 4.9 1 1 5 6 6 6 0 Septum formation initiator NPV_P10 PF05531.12 EKX43006.1 - 3.1 8.3 11.8 1.6 9.2 0.3 3.3 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Fez1 PF06818.15 EKX43006.1 - 3.2 8.2 29.0 73 3.7 29.0 2.2 1 1 0 1 1 1 0 Fez1 DUF4407 PF14362.6 EKX43006.1 - 3.2 7.0 19.2 7.3 5.8 19.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TolA_bind_tri PF16331.5 EKX43006.1 - 3.6 7.7 22.8 0.93 9.6 6.8 3.8 1 1 3 4 4 4 0 TolA binding protein trimerisation DUF641 PF04859.12 EKX43006.1 - 4 7.8 31.1 2.3 8.5 2.0 4.1 2 2 2 4 4 4 0 Plant protein of unknown function (DUF641) Jnk-SapK_ap_N PF09744.9 EKX43006.1 - 4.1 7.6 34.5 0.81 9.9 12.7 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF948 PF06103.11 EKX43006.1 - 4.7 7.6 7.5 4.7 7.5 0.2 3.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ERM PF00769.19 EKX43006.1 - 5.1 6.8 37.9 11 5.7 37.9 2.0 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF16 PF01519.16 EKX43006.1 - 5.5 7.5 20.7 4.1 8.0 10.5 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 CdiI_2 PF18593.1 EKX43006.1 - 7.6 7.3 8.3 2.3 8.9 1.1 2.9 1 1 0 3 3 3 0 CdiI immunity protein DUF4055 PF13264.6 EKX43006.1 - 9.3 6.4 8.4 2.5 8.2 2.9 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4055) Leu_Phe_trans PF03588.14 EKX43008.1 - 3.3e-28 98.3 0.0 4.4e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Leucyl/phenylalanyl-tRNA protein transferase Exo_endo_phos PF03372.23 EKX43009.1 - 0.0041 16.7 0.0 0.0045 16.5 0.0 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Sugar_tr PF00083.24 EKX43011.1 - 2e-46 158.8 19.8 4.4e-46 157.7 19.8 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EKX43011.1 - 3.7e-21 75.5 30.1 6.5e-19 68.1 33.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Choline_transpo PF04515.12 EKX43012.1 - 2.4e-52 178.2 21.2 2.4e-52 178.2 21.2 2.0 2 0 0 2 2 2 1 Plasma-membrane choline transporter DAGK_cat PF00781.24 EKX43014.1 - 1.4e-27 95.8 0.0 2.7e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain VWA_3_C PF18571.1 EKX43014.1 - 0.0046 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A C-terminal domain Myb_DNA-binding PF00249.31 EKX43017.1 - 6.8e-07 29.4 0.2 4.5e-06 26.7 0.2 2.1 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EKX43017.1 - 0.037 13.9 0.4 0.12 12.2 0.1 1.9 2 0 0 2 2 2 0 Myb DNA-binding like SAM_2 PF07647.17 EKX43018.1 - 0.0041 17.2 0.1 0.013 15.6 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EKX43018.1 - 0.026 15.0 0.4 0.083 13.4 0.4 1.9 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 EKX43018.1 - 0.067 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Ste50p, sterile alpha motif EF-hand_8 PF13833.6 EKX43018.1 - 0.11 12.3 0.0 0.44 10.4 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair LapA_dom PF06305.11 EKX43019.1 - 0.046 13.5 1.6 0.089 12.6 0.2 2.0 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DivIC PF04977.15 EKX43019.1 - 0.052 13.3 0.0 0.92 9.3 0.0 2.0 2 0 0 2 2 2 0 Septum formation initiator PikAIV_N PF18605.1 EKX43019.1 - 0.17 11.5 1.6 0.33 10.6 1.6 1.5 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DUF2570 PF10828.8 EKX43019.1 - 0.18 11.6 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) CENP-F_leu_zip PF10473.9 EKX43019.1 - 0.18 11.8 1.5 0.9 9.6 0.2 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA PF00004.29 EKX43020.1 - 1.5e-41 142.0 0.0 3.4e-41 140.8 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EKX43020.1 - 3.4e-13 49.2 0.3 5.5e-13 48.5 0.3 1.3 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EKX43020.1 - 2.7e-09 37.6 0.0 7.6e-05 23.2 0.1 2.5 1 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 EKX43020.1 - 8.4e-07 29.1 0.2 5.2e-06 26.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EKX43020.1 - 3.7e-06 27.2 0.1 0.011 16.0 0.0 2.6 2 1 1 3 3 3 2 AAA domain RuvB_N PF05496.12 EKX43020.1 - 0.00011 22.0 0.0 0.00032 20.5 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EKX43020.1 - 0.00097 18.6 0.1 0.0043 16.4 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EKX43020.1 - 0.0013 18.9 0.0 0.0049 17.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EKX43020.1 - 0.0018 17.6 0.1 0.09 12.0 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin TIP49 PF06068.13 EKX43020.1 - 0.0027 17.0 0.0 0.0043 16.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 EKX43020.1 - 0.006 16.7 0.0 0.016 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EKX43020.1 - 0.01 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 EKX43020.1 - 0.011 15.5 0.0 0.16 11.6 0.0 2.4 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.6 EKX43020.1 - 0.015 15.6 0.0 0.035 14.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EKX43020.1 - 0.016 15.1 0.0 0.21 11.5 0.0 2.1 1 1 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 EKX43020.1 - 0.022 15.3 0.0 0.04 14.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EKX43020.1 - 0.028 14.9 0.0 0.077 13.4 0.0 1.7 1 1 1 2 2 2 0 AAA domain AAA_11 PF13086.6 EKX43020.1 - 0.04 13.7 0.0 0.099 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EKX43020.1 - 0.045 13.3 0.0 0.096 12.2 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 EKX43020.1 - 0.047 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EKX43020.1 - 0.05 13.2 0.3 0.16 11.5 0.3 2.0 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EKX43020.1 - 0.052 13.3 0.5 0.36 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 EKX43020.1 - 0.08 12.7 0.1 1.8 8.2 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase AAA_28 PF13521.6 EKX43020.1 - 0.099 12.9 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 EKX43020.1 - 0.1 12.7 0.0 0.27 11.4 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 EKX43020.1 - 0.11 13.0 0.3 0.37 11.3 0.0 2.0 3 0 0 3 3 2 0 ABC transporter RNA_helicase PF00910.22 EKX43020.1 - 0.11 12.9 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_32 PF13654.6 EKX43020.1 - 0.13 11.0 0.4 0.33 9.7 0.2 1.6 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EKX43020.1 - 0.14 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Torsin PF06309.11 EKX43020.1 - 0.17 12.0 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Torsin FtsH_ext PF06480.15 EKX43021.1 - 0.006 16.9 0.7 0.0095 16.3 0.0 1.7 2 0 0 2 2 2 1 FtsH Extracellular Kelch_1 PF01344.25 EKX43022.1 - 1.2e-05 24.8 0.5 0.089 12.4 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 EKX43022.1 - 0.00014 22.0 0.7 0.35 11.2 0.0 4.3 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.6 EKX43022.1 - 0.0032 17.4 1.6 2.7 8.1 0.0 3.6 4 0 0 4 4 4 2 Kelch motif tRNA_U5-meth_tr PF05958.11 EKX43023.1 - 1.2e-85 287.7 0.2 3.6e-85 286.1 0.2 1.7 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Myb_DNA-binding PF00249.31 EKX43023.1 - 3.3e-09 36.8 0.0 9.2e-09 35.4 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3225 PF11533.8 EKX43023.1 - 0.016 14.9 0.8 1.7 8.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3225) GAS PF13851.6 EKX43023.1 - 0.02 14.3 3.1 0.048 13.0 3.1 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Cnn_1N PF07989.11 EKX43023.1 - 0.025 14.8 1.6 0.066 13.4 1.6 1.7 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 Methyltransf_4 PF02390.17 EKX43023.1 - 0.054 13.0 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.6 EKX43023.1 - 0.055 14.2 0.0 0.19 12.4 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EKX43023.1 - 0.13 12.9 0.0 0.57 10.9 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain DREV PF05219.12 EKX43023.1 - 0.14 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Csm1_N PF18504.1 EKX43023.1 - 0.15 12.5 2.9 0.41 11.0 2.9 1.7 1 0 0 1 1 1 0 Csm1 N-terminal domain CorA PF01544.18 EKX43023.1 - 0.53 9.6 2.6 3.9 6.7 2.4 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein TIR_2 PF13676.6 EKX43024.1 - 0.11 13.1 0.0 8.8 7.0 0.0 2.6 2 0 0 2 2 2 0 TIR domain Peptidase_M24 PF00557.24 EKX43025.1 - 4.4e-50 170.3 0.1 5.2e-50 170.1 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Antimicrobial22 PF16047.5 EKX43025.1 - 0.16 11.9 0.0 0.45 10.4 0.0 1.8 1 0 0 1 1 1 0 Frog antimicrobial peptide HAGH_C PF16123.5 EKX43026.1 - 6.7e-24 84.2 0.0 1.1e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EKX43026.1 - 1e-12 48.5 2.2 6e-11 42.7 2.2 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EKX43026.1 - 0.0014 18.2 0.2 0.0068 15.9 0.2 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EKX43026.1 - 0.067 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain DUF3631 PF12307.8 EKX43027.1 - 0.2 11.9 0.1 0.37 11.0 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3631) Acyltransferase PF01553.21 EKX43028.1 - 1.7e-17 63.3 0.0 2.8e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EKX43028.1 - 1.3e-12 47.7 0.1 3.1e-12 46.4 0.1 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus Carb_anhydrase PF00194.21 EKX43029.1 - 7.5e-57 192.8 0.0 9.4e-57 192.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Mucin15 PF15672.5 EKX43029.1 - 0.0087 15.6 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Cell-membrane associated Mucin15 Tweety PF04906.13 EKX43029.1 - 0.04 12.6 0.0 0.06 12.0 0.0 1.1 1 0 0 1 1 1 0 Tweety dsrm PF00035.26 EKX43030.1 - 2.6e-30 104.9 6.5 3.8e-10 40.3 0.4 3.9 4 0 0 4 4 4 3 Double-stranded RNA binding motif DND1_DSRM PF14709.7 EKX43030.1 - 3.5e-06 27.2 0.8 0.071 13.4 0.3 4.1 3 1 0 3 3 3 3 double strand RNA binding domain from DEAD END PROTEIN 1 Sugar_tr PF00083.24 EKX43031.1 - 3.9e-05 22.7 12.9 9.9e-05 21.4 12.3 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EKX43031.1 - 0.0032 16.5 31.4 0.01 14.8 31.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Abhydrolase_1 PF00561.20 EKX43032.1 - 0.0023 17.7 0.1 0.0026 17.5 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold TIR_2 PF13676.6 EKX43033.1 - 0.063 13.9 0.0 9.2 6.9 0.0 2.8 2 0 0 2 2 2 0 TIR domain DUF4149 PF13664.6 EKX43033.1 - 0.14 12.5 2.3 0.3 11.4 1.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4149) PhoLip_ATPase_C PF16212.5 EKX43033.1 - 0.17 11.6 6.4 0.3 10.8 6.4 1.3 1 0 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal TFCD_C PF12612.8 EKX43034.1 - 4.2e-19 69.1 0.0 1.4e-18 67.4 0.0 1.9 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 EKX43034.1 - 1.2 9.6 6.4 12 6.5 0.1 5.1 4 1 0 4 4 4 0 HEAT repeat Phage_GPO PF05929.11 EKX43035.1 - 0.01 15.5 0.5 0.02 14.6 0.1 1.6 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase eIF-1a PF01176.19 EKX43036.1 - 4.4e-23 80.9 0.0 5.4e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 RsgA_N PF16745.5 EKX43036.1 - 0.0006 19.5 0.0 0.00075 19.2 0.0 1.2 1 0 0 1 1 1 1 RsgA N-terminal domain Ribosomal_L18A PF01775.17 EKX43037.1 - 9e-46 154.9 3.5 1.1e-45 154.6 3.5 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A DUF1365 PF07103.11 EKX43039.1 - 1.5e-17 64.1 0.0 1.1e-13 51.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1365) YtxC PF08812.11 EKX43041.1 - 0.21 11.2 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 YtxC-like family Ank_4 PF13637.6 EKX43042.1 - 1.7e-09 38.0 0.0 3.7e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) EF-hand_8 PF13833.6 EKX43042.1 - 3.6e-09 36.3 0.1 8e-09 35.2 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 EKX43042.1 - 1.2e-08 35.2 0.0 2.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX43042.1 - 2.9e-07 29.9 0.6 0.038 13.9 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain Ank PF00023.30 EKX43042.1 - 5.8e-07 29.7 0.0 0.0038 17.6 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EKX43042.1 - 7.2e-07 29.0 0.0 0.033 14.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EKX43042.1 - 1.4e-06 28.8 0.0 3.6e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) EF-hand_1 PF00036.32 EKX43042.1 - 2.2e-05 23.7 0.4 0.0015 17.9 0.2 2.4 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 EKX43042.1 - 0.0006 19.2 0.2 0.0014 18.1 0.2 1.5 1 0 0 1 1 1 1 EF hand Ank_5 PF13857.6 EKX43042.1 - 0.00079 19.7 0.0 0.0086 16.4 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Hexapep PF00132.24 EKX43043.1 - 3.5e-05 23.3 5.3 0.0024 17.5 0.6 4.4 4 1 1 5 5 5 2 Bacterial transferase hexapeptide (six repeats) SesA PF17107.5 EKX43043.1 - 0.089 13.0 2.7 0.13 12.5 2.7 1.2 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases PARP PF00644.20 EKX43044.1 - 1.3e-60 204.4 4.6 3.5e-60 202.9 0.0 2.6 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 EKX43044.1 - 3.7e-41 140.4 0.2 8.5e-41 139.2 0.2 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain zf-PARP PF00645.18 EKX43044.1 - 2.2e-36 124.6 3.8 1.4e-18 67.5 0.0 3.1 3 0 0 3 3 2 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region WGR PF05406.15 EKX43044.1 - 9.3e-20 70.5 0.1 9.3e-20 70.5 0.1 2.5 4 0 0 4 4 2 1 WGR domain PADR1 PF08063.12 EKX43044.1 - 3.7e-12 45.8 5.6 4.9e-12 45.4 3.1 2.2 2 0 0 2 2 2 1 PADR1 (NUC008) domain BRCT_2 PF16589.5 EKX43044.1 - 2.2e-06 28.0 0.0 6.6e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EKX43044.1 - 0.0015 18.4 0.2 0.0039 17.1 0.2 1.8 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 EKX43044.1 - 0.039 14.3 0.0 0.13 12.7 0.0 1.9 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain LCIB_C_CA PF18599.1 EKX43044.1 - 0.23 10.7 1.7 0.53 9.5 1.7 1.5 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases tRNA-synt_1g PF09334.11 EKX43044.1 - 0.33 9.7 1.7 0.59 8.8 1.7 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (M) PIN_8 PF18476.1 EKX43044.1 - 8.6 6.1 8.9 2.5 7.9 0.1 3.1 3 0 0 3 3 3 0 PIN like domain PADR1 PF08063.12 EKX43045.1 - 7.7e-10 38.4 2.3 1e-09 38.0 2.3 1.2 1 0 0 1 1 1 1 PADR1 (NUC008) domain tRNA-synt_1g PF09334.11 EKX43045.1 - 0.011 14.5 0.2 0.014 14.2 0.2 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (M) DUF3023 PF11224.8 EKX43045.1 - 0.015 15.1 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3023) VP_N-CPKC PF11475.8 EKX43045.1 - 0.078 12.9 0.3 0.2 11.6 0.3 1.7 1 0 0 1 1 1 0 Virion protein N terminal domain T3SS_basalb_I PF17001.5 EKX43045.1 - 0.12 13.0 0.1 0.15 12.7 0.1 1.1 1 0 0 1 1 1 0 Type III secretion basal body protein I, YscI, HrpB, PscI WGR PF05406.15 EKX43046.1 - 2.5e-20 72.3 0.0 7.2e-20 70.8 0.0 1.8 1 0 0 1 1 1 1 WGR domain BRCT_2 PF16589.5 EKX43046.1 - 3.1e-07 30.7 0.0 7.3e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EKX43046.1 - 0.00019 21.3 0.2 0.00058 19.8 0.0 1.9 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 EKX43046.1 - 0.0016 18.8 0.0 0.0063 16.9 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EKX43046.1 - 0.13 12.6 0.0 0.41 11.0 0.0 1.9 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain SLATT_1 PF18181.1 EKX43047.1 - 4.3e-14 52.5 0.7 4.3e-14 52.5 0.7 3.0 3 0 0 3 3 3 1 SMODS and SLOG-associating 2TM effector domain 1 DUF4231 PF14015.6 EKX43047.1 - 4e-08 33.7 0.8 4e-08 33.7 0.8 4.3 4 1 0 4 4 4 2 Protein of unknown function (DUF4231) SLATT_3 PF18184.1 EKX43047.1 - 0.00044 20.4 0.4 0.00044 20.4 0.4 3.0 3 0 0 3 3 3 1 SMODS and SLOG-associating 2TM effector domain 3 FancD2 PF14631.6 EKX43047.1 - 0.012 13.0 0.6 0.025 12.0 0.1 1.6 2 0 0 2 2 2 0 Fanconi anaemia protein FancD2 nuclease PAP_fibrillin PF04755.12 EKX43047.1 - 0.014 15.4 0.2 0.05 13.5 0.0 2.1 3 0 0 3 3 3 0 PAP_fibrillin LSDAT_prok PF18171.1 EKX43047.1 - 0.033 13.4 0.2 0.087 12.0 0.0 1.7 2 0 0 2 2 2 0 SLOG in TRPM, prokaryote DUF1980 PF09323.10 EKX43047.1 - 0.054 13.4 0.2 0.13 12.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF1211 PF06736.11 EKX43047.1 - 0.46 11.0 3.5 1.2 9.6 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1211) TFA2_Winged_2 PF18121.1 EKX43048.1 - 5.6 6.7 12.0 1.4 8.7 3.9 3.3 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 ARID PF01388.21 EKX43049.1 - 1.2e-23 83.6 0.5 1.8e-13 50.9 0.1 2.8 2 0 0 2 2 2 2 ARID/BRIGHT DNA binding domain DUF1841 PF08897.11 EKX43049.1 - 0.024 14.7 0.0 0.078 13.0 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1841) Ion_trans_2 PF07885.16 EKX43050.1 - 8.7e-12 44.8 9.6 8.7e-12 44.8 9.6 2.5 2 1 0 2 2 2 1 Ion channel EF-hand_1 PF00036.32 EKX43050.1 - 4.7e-08 32.0 0.4 0.0084 15.6 0.0 5.3 5 0 0 5 5 5 1 EF hand Lig_chan PF00060.26 EKX43050.1 - 2.2e-07 30.8 2.1 4.6e-07 29.8 2.1 1.6 1 0 0 1 1 1 1 Ligand-gated ion channel EF-hand_5 PF13202.6 EKX43050.1 - 2.4e-06 26.8 2.1 0.1 12.1 0.0 6.0 6 0 0 6 6 6 1 EF hand EF-hand_7 PF13499.6 EKX43050.1 - 1.1e-05 25.8 2.2 0.018 15.5 0.0 4.4 3 2 1 4 4 4 1 EF-hand domain pair Ion_trans PF00520.31 EKX43050.1 - 9.7e-05 21.7 5.8 9.7e-05 21.7 5.8 2.5 2 1 0 2 2 2 1 Ion transport protein EF-hand_6 PF13405.6 EKX43050.1 - 0.00042 20.0 0.6 15 5.8 0.0 5.3 5 1 0 5 5 5 1 EF-hand domain SBP_bac_3 PF00497.20 EKX43050.1 - 0.0023 17.4 0.0 0.091 12.2 0.0 2.8 2 1 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 EF-hand_8 PF13833.6 EKX43050.1 - 0.0086 15.9 1.5 0.28 11.1 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain pair ARL2_Bind_BART PF11527.8 EKX43051.1 - 1.4e-13 51.0 4.2 1.5e-13 50.9 4.2 1.0 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART DUF3447 PF11929.8 EKX43051.1 - 0.02 14.9 1.5 0.026 14.5 0.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) LAGLIDADG_WhiA PF14527.6 EKX43051.1 - 0.032 14.3 0.1 0.047 13.8 0.1 1.3 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain Cofilin_ADF PF00241.20 EKX43052.1 - 7.9e-35 119.3 0.3 8.8e-35 119.1 0.3 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein EF-hand_7 PF13499.6 EKX43053.1 - 1.9e-10 41.0 1.2 4.2e-10 39.9 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX43053.1 - 1.4e-08 33.7 1.5 0.002 17.6 0.6 3.2 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EKX43053.1 - 6.9e-08 31.8 0.2 0.026 14.4 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 EKX43053.1 - 7.7e-05 22.0 0.2 0.37 10.4 0.0 3.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX43053.1 - 0.0031 17.3 2.0 0.024 14.5 0.5 2.9 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_9 PF14658.6 EKX43053.1 - 0.016 15.6 0.0 0.061 13.7 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain DUF3829 PF12889.7 EKX43053.1 - 0.02 14.4 0.4 0.037 13.5 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Syntaxin_2 PF14523.6 EKX43053.1 - 0.034 14.5 1.1 0.13 12.7 1.1 2.0 1 1 0 1 1 1 0 Syntaxin-like protein Glutaredoxin PF00462.24 EKX43053.1 - 0.043 14.0 0.3 0.36 11.1 0.2 2.5 2 0 0 2 2 2 0 Glutaredoxin DNA_pol3_beta PF00712.19 EKX43053.1 - 0.054 13.6 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain DUF836 PF05768.14 EKX43053.1 - 0.12 12.8 2.5 0.17 12.3 1.2 1.9 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Cauli_DNA-bind PF03310.13 EKX43053.1 - 0.79 9.8 8.3 0.65 10.1 0.8 2.6 2 1 0 2 2 2 0 Caulimovirus DNA-binding protein DndB PF14072.6 EKX43054.1 - 0.0015 17.8 0.2 0.01 15.1 0.0 2.2 1 1 2 3 3 3 1 DNA-sulfur modification-associated DUF262 PF03235.14 EKX43054.1 - 0.0049 17.1 0.0 0.0049 17.1 0.0 2.2 1 1 0 2 2 2 1 Protein of unknown function DUF262 ParBc PF02195.18 EKX43054.1 - 0.0094 16.2 0.0 0.027 14.7 0.0 1.8 1 0 0 1 1 1 1 ParB-like nuclease domain TPR_MLP1_2 PF07926.12 EKX43054.1 - 0.28 11.3 13.0 7.3 6.7 8.7 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Sec16 PF12932.7 EKX43054.1 - 0.3 11.7 2.1 1 10.0 0.1 2.6 3 0 0 3 3 3 0 Vesicle coat trafficking protein Sec16 mid-region DUF4407 PF14362.6 EKX43054.1 - 6 6.1 6.8 1 8.6 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4570 PF15134.6 EKX43054.1 - 8.7 6.4 12.2 19 5.3 6.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4570) NUDIX PF00293.28 EKX43055.1 - 3.5e-06 27.1 0.0 5.3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF4256 PF14066.6 EKX43055.1 - 0.01 15.5 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4256) PDZ_2 PF13180.6 EKX43056.1 - 6.9e-09 35.9 0.2 9e-09 35.5 0.2 1.1 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX43056.1 - 2.6e-08 34.1 0.8 3.7e-08 33.6 0.8 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX43056.1 - 7.5e-07 28.9 0.6 5.8e-06 26.1 0.6 2.0 1 1 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX43056.1 - 0.00013 21.9 0.1 0.00022 21.2 0.1 1.3 1 0 0 1 1 1 1 Tricorn protease PDZ domain CHASE2 PF05226.11 EKX43058.1 - 0.19 11.4 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 CHASE2 domain PQQ_2 PF13360.6 EKX43059.1 - 4.1e-66 223.0 36.5 4.9e-20 72.1 3.0 6.7 2 2 4 6 6 6 5 PQQ-like domain PQQ PF01011.21 EKX43059.1 - 8.4e-42 139.2 6.2 7.2e-06 25.7 0.0 12.2 12 0 0 12 12 12 9 PQQ enzyme repeat PQQ_3 PF13570.6 EKX43059.1 - 3e-35 119.8 33.8 9.4e-07 29.1 0.6 14.3 15 0 0 15 15 15 8 PQQ-like domain ANAPC4_WD40 PF12894.7 EKX43059.1 - 4e-11 43.0 0.0 0.054 13.8 0.0 5.8 6 0 0 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EKX43059.1 - 3.1e-10 39.7 2.8 0.0061 16.5 0.0 6.7 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat TNFR_c6 PF00020.18 EKX43059.1 - 0.052 14.0 4.7 0.12 12.8 4.7 1.6 1 0 0 1 1 1 0 TNFR/NGFR cysteine-rich region ESF1 PF18209.1 EKX43059.1 - 0.067 13.1 1.0 0.11 12.4 1.0 1.4 1 0 0 1 1 1 0 Embryo surrounding factor 1 Methyltransf_21 PF05050.12 EKX43060.1 - 0.048 13.7 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase FkbM domain zf-RING_2 PF13639.6 EKX43061.1 - 3.5e-13 49.6 12.6 4.3e-13 49.4 12.6 1.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EKX43061.1 - 6.7e-09 35.3 8.4 6.7e-09 35.3 8.4 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EKX43061.1 - 1.2e-06 28.2 12.0 1.6e-06 27.8 12.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX43061.1 - 5.9e-06 26.1 11.6 8.1e-06 25.6 11.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX43061.1 - 7e-06 26.2 12.4 1.5e-05 25.2 12.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EKX43061.1 - 0.0018 18.2 9.6 0.0026 17.7 9.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EKX43061.1 - 0.0031 17.5 5.4 0.0031 17.5 5.4 2.2 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EKX43061.1 - 0.0056 16.5 12.1 0.0083 16.0 12.1 1.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EKX43061.1 - 0.066 13.3 8.4 0.21 11.7 8.4 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 EKX43061.1 - 2.8 8.2 13.4 33 4.8 13.4 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain SNF2_N PF00176.23 EKX43062.1 - 2.6e-28 98.8 0.1 9.1e-28 97.0 0.1 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain WW PF00397.26 EKX43062.1 - 1.5e-05 25.0 1.2 3.7e-05 23.7 1.2 1.7 1 0 0 1 1 1 1 WW domain ResIII PF04851.15 EKX43062.1 - 0.00019 21.5 2.0 0.0011 19.0 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DnaJ PF00226.31 EKX43063.1 - 4.2e-10 39.6 0.0 1.2e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain DUF2956 PF11169.8 EKX43063.1 - 0.78 10.0 6.4 7.1 6.9 6.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2956) TBCC_N PF16752.5 EKX43063.1 - 5.7 7.4 12.0 11 6.5 9.1 2.2 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain NDUF_B6 PF09782.9 EKX43064.1 - 0.022 14.9 0.3 0.54 10.4 0.1 2.8 3 0 0 3 3 3 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit DUF3136 PF11334.8 EKX43064.1 - 0.036 13.9 0.1 17 5.3 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3136) LRR_6 PF13516.6 EKX43065.1 - 1e-12 47.0 17.4 0.013 15.5 0.0 7.1 8 0 0 8 8 8 4 Leucine Rich repeat LRR_1 PF00560.33 EKX43065.1 - 0.014 15.8 3.7 76 4.5 0.0 5.7 6 1 0 6 6 6 0 Leucine Rich Repeat Med26 PF08711.11 EKX43065.1 - 0.055 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 TFIIS helical bundle-like domain LRR_8 PF13855.6 EKX43065.1 - 0.16 11.7 12.1 30 4.5 0.6 4.9 3 2 1 4 4 4 0 Leucine rich repeat LRR_4 PF12799.7 EKX43065.1 - 0.22 12.0 7.2 27 5.4 0.1 4.5 2 2 3 5 5 5 0 Leucine Rich repeats (2 copies) TPR_17 PF13431.6 EKX43067.1 - 5.7e-06 26.4 0.2 0.12 12.9 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX43067.1 - 0.00016 22.1 1.9 0.036 14.6 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX43067.1 - 0.0021 18.1 4.9 0.034 14.3 0.4 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX43067.1 - 0.0024 18.0 1.6 0.0065 16.7 0.3 2.3 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EKX43067.1 - 0.012 16.3 1.5 7.5 7.7 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat UCR_hinge PF02320.16 EKX43067.1 - 0.038 14.2 1.4 0.11 12.8 0.3 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein LPD30 PF18850.1 EKX43067.1 - 0.046 13.5 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Large polyvalent protein associated domain 30 TPR_16 PF13432.6 EKX43067.1 - 0.26 12.0 7.5 0.26 12.0 1.1 3.0 2 1 2 4 4 4 0 Tetratricopeptide repeat DUF2437 PF10370.9 EKX43068.1 - 0.2 12.6 0.0 0.33 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2437) Tetraspanin PF00335.20 EKX43069.1 - 2.5e-09 37.2 23.0 1.7e-08 34.5 23.0 2.2 1 1 0 1 1 1 1 Tetraspanin family DUF4064 PF13273.6 EKX43069.1 - 0.064 13.5 13.0 10 6.5 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF1995 PF09353.10 EKX43070.1 - 1.2e-22 81.0 0.0 2.5e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) IPP-2 PF04979.14 EKX43072.1 - 1e-15 58.6 30.0 5.6e-14 53.0 14.0 2.2 1 1 1 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) Peptidase_C37 PF05416.12 EKX43072.1 - 0.13 10.7 12.3 0.15 10.5 12.3 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase LpxC PF03331.13 EKX43073.1 - 4.7e-71 239.5 0.1 4.4e-68 229.7 0.1 2.9 1 1 0 1 1 1 1 UDP-3-O-acyl N-acetylglycosamine deacetylase PGAP1 PF07819.13 EKX43074.1 - 3.2e-56 190.6 0.0 5.3e-56 189.9 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EKX43074.1 - 4e-05 24.3 2.3 4.2e-05 24.2 0.3 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 EKX43074.1 - 0.001 18.9 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_3 PF07859.13 EKX43074.1 - 0.061 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EKX43074.1 - 0.083 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 EKX43074.1 - 0.09 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF1659 PF07872.11 EKX43075.1 - 0.17 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1659) ADH_zinc_N_2 PF13602.6 EKX43076.1 - 1.9e-22 80.8 0.0 3.8e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EKX43076.1 - 8.1e-11 42.0 0.0 1.5e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EKX43076.1 - 1.3e-06 28.2 0.2 3.2e-05 23.8 0.0 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Sacchrp_dh_NADP PF03435.18 EKX43076.1 - 0.024 14.9 0.0 0.047 14.0 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain PRR18 PF15671.5 EKX43077.1 - 0.0038 17.2 0.2 0.0074 16.2 0.2 1.4 1 0 0 1 1 1 1 Proline-rich protein family 18 tRNA-synt_2c PF01411.19 EKX43078.1 - 6.7e-200 665.3 0.0 9.3e-200 664.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) DHHA1 PF02272.19 EKX43078.1 - 2.2e-16 60.5 4.1 5.1e-16 59.3 4.1 1.6 1 0 0 1 1 1 1 DHHA1 domain tRNA_SAD PF07973.14 EKX43078.1 - 2.4e-13 49.9 0.0 5.6e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain PCRF PF03462.18 EKX43078.1 - 0.044 13.6 0.1 0.091 12.6 0.1 1.5 1 0 0 1 1 1 0 PCRF domain SAM_1 PF00536.30 EKX43079.1 - 1.7e-13 50.8 0.0 2.2e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EKX43079.1 - 6.8e-12 45.3 0.0 9.9e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Mak16 PF04874.14 EKX43081.1 - 2.7 8.7 12.7 4.2 8.0 12.7 1.3 1 0 0 1 1 1 0 Mak16 protein C-terminal region DNA_pol_phi PF04931.13 EKX43081.1 - 4.3 5.3 15.3 4.9 5.1 15.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi cNMP_binding PF00027.29 EKX43082.1 - 2.6e-07 30.6 0.0 3.7e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain YdaS_antitoxin PF15943.5 EKX43083.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MTP18 PF10558.9 EKX43084.1 - 9e-37 126.7 3.7 1.1e-17 64.6 0.4 2.0 1 1 1 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) FAM199X PF15814.5 EKX43085.1 - 3.7 6.5 8.7 5.3 6.0 8.7 1.2 1 0 0 1 1 1 0 Protein family FAM199X CLASP_N PF12348.8 EKX43086.1 - 7.8e-33 113.9 9.3 5.6e-11 42.5 0.0 5.7 6 1 1 7 7 7 4 CLASP N terminal HEAT_2 PF13646.6 EKX43086.1 - 1.2e-08 35.2 11.3 2.8 8.4 0.0 9.0 8 1 2 10 10 10 4 HEAT repeats Xpo1 PF08389.12 EKX43086.1 - 2.5e-08 34.1 0.7 0.0013 18.8 0.0 4.9 4 1 1 5 5 5 2 Exportin 1-like protein HEAT PF02985.22 EKX43086.1 - 4.9e-08 32.6 20.4 0.48 10.8 0.1 10.3 12 0 0 12 12 12 2 HEAT repeat Cnd1 PF12717.7 EKX43086.1 - 2.9e-06 27.4 13.2 0.12 12.4 0.1 6.6 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EKX43086.1 - 0.0031 18.0 8.4 2.4 8.7 0.0 6.5 6 1 1 7 7 7 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EKX43086.1 - 0.0077 16.8 0.9 0.33 11.6 0.0 4.0 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region NUC173 PF08161.12 EKX43086.1 - 0.045 13.4 0.4 9.8 5.8 0.0 4.0 4 1 1 5 5 5 0 NUC173 domain RTP1_C1 PF10363.9 EKX43086.1 - 2.4 8.4 4.7 19 5.5 0.0 4.6 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF1479 PF07350.12 EKX43087.1 - 3.8e-92 309.2 0.1 5.7e-92 308.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PAH PF02671.21 EKX43087.1 - 3e-06 27.2 0.1 1.2e-05 25.3 0.1 2.1 1 0 0 1 1 1 1 Paired amphipathic helix repeat PhyH PF05721.13 EKX43087.1 - 0.0018 18.6 0.2 0.0059 16.9 0.2 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) ART PF01129.18 EKX43087.1 - 0.052 12.8 0.1 0.085 12.1 0.1 1.3 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase FbpA PF05833.11 EKX43087.1 - 0.086 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Peptidase_C1 PF00112.23 EKX43088.1 - 3.3e-66 223.5 2.1 3.8e-66 223.3 2.1 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EKX43088.1 - 0.0015 17.4 1.9 0.07 11.9 0.4 2.1 2 0 0 2 2 2 2 Peptidase C1-like family SNF2_N PF00176.23 EKX43089.1 - 1.4e-74 251.0 0.0 2.1e-74 250.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX43089.1 - 4.4e-09 36.7 0.0 1.2e-08 35.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Prok-RING_4 PF14447.6 EKX43089.1 - 4.9e-07 29.5 13.9 1.7e-06 27.8 13.9 2.0 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EKX43089.1 - 0.00084 19.2 13.9 0.00084 19.2 13.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX43089.1 - 0.0012 18.7 15.5 0.0012 18.7 15.5 2.0 2 0 0 2 2 2 1 zinc-RING finger domain F-box-like PF12937.7 EKX43089.1 - 0.014 15.2 0.3 0.054 13.4 0.0 2.2 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 EKX43089.1 - 0.019 14.8 0.0 0.052 13.5 0.0 1.7 1 0 0 1 1 1 0 F-box domain zf-RING_10 PF16685.5 EKX43089.1 - 0.13 12.4 8.7 0.34 11.1 8.7 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 EKX43089.1 - 1.6 8.8 12.2 2.6 8.1 8.4 2.7 2 0 0 2 2 2 0 RING-type zinc-finger GST_N_3 PF13417.6 EKX43090.1 - 1.1e-16 60.9 0.0 2.2e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EKX43090.1 - 2e-13 50.5 0.0 3.4e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EKX43090.1 - 3.4e-08 33.7 0.0 6.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EKX43090.1 - 1.2e-06 28.4 0.0 2.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EKX43090.1 - 1.7e-05 25.4 0.0 2.9e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EKX43090.1 - 0.0036 17.5 0.0 0.0075 16.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EKX43090.1 - 0.0038 17.4 0.1 0.0065 16.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 EKX43090.1 - 0.093 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain zf-RING_2 PF13639.6 EKX43091.1 - 6.7e-10 39.2 14.8 6.7e-10 39.2 14.8 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX43091.1 - 5.4e-07 29.3 15.9 5.4e-07 29.3 15.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX43091.1 - 3.2e-05 23.8 7.2 6.9e-05 22.8 7.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EKX43091.1 - 6.1e-05 23.2 21.3 0.00022 21.5 18.6 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EKX43091.1 - 0.00014 21.5 8.0 0.00014 21.5 8.0 2.2 2 1 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 EKX43091.1 - 0.00079 19.2 18.8 0.00079 19.2 18.8 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EKX43091.1 - 0.00093 19.0 14.1 0.0016 18.3 14.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EKX43091.1 - 0.028 14.0 16.9 0.046 13.4 16.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EKX43091.1 - 0.037 14.1 13.0 0.16 12.1 13.0 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EKX43091.1 - 1.1 9.3 17.8 2.6 8.1 17.8 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Ion_trans PF00520.31 EKX43094.1 - 2.1e-14 53.3 5.5 3e-14 52.8 5.5 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX43094.1 - 1.3e-12 47.5 0.5 2.7e-12 46.5 0.5 1.6 1 0 0 1 1 1 1 Ion channel cNMP_binding PF00027.29 EKX43094.1 - 0.0031 17.6 0.0 0.015 15.4 0.0 2.1 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Flavokinase PF01687.17 EKX43095.1 - 3.9e-33 114.1 0.0 4.4e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase NHL PF01436.21 EKX43097.1 - 1.3e-16 59.6 0.9 0.0004 20.3 0.0 6.7 7 0 0 7 7 7 3 NHL repeat SGL PF08450.12 EKX43097.1 - 5.7e-06 26.1 2.2 0.00056 19.6 1.1 3.3 1 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 EKX43097.1 - 1.7e-05 25.0 0.1 0.29 11.4 0.0 4.0 4 0 0 4 4 4 2 Arylesterase Lactonase PF10282.9 EKX43097.1 - 0.00048 19.5 0.1 0.0011 18.4 0.1 1.7 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Str_synth PF03088.16 EKX43097.1 - 0.0049 17.0 0.1 2.9 8.1 0.0 4.3 5 0 0 5 5 5 1 Strictosidine synthase RVT_1 PF00078.27 EKX43098.1 - 3.1e-07 30.1 0.0 5.3e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ORC5_C PF14630.6 EKX43098.1 - 0.024 14.1 0.1 0.024 14.1 0.1 2.4 3 0 0 3 3 3 0 Origin recognition complex (ORC) subunit 5 C-terminus Herpes_UL4 PF03277.13 EKX43098.1 - 0.16 11.5 0.9 2.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Herpesvirus UL4 family TFIIA PF03153.13 EKX43098.1 - 5.2 7.0 14.1 6.2 6.7 1.6 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RVT_1 PF00078.27 EKX43099.1 - 0.00061 19.4 0.0 0.0031 17.0 0.0 1.9 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ORC5_C PF14630.6 EKX43099.1 - 0.0089 15.6 0.2 0.046 13.2 0.1 1.9 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus DSPc PF00782.20 EKX43101.1 - 6e-07 29.4 0.9 1.1e-06 28.5 0.4 1.7 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EKX43101.1 - 2.7e-05 24.3 0.0 4e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EKX43101.1 - 0.00031 20.4 0.0 0.00034 20.3 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX43101.1 - 0.00063 19.9 0.0 0.00076 19.6 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 EKX43101.1 - 0.13 11.8 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family WW PF00397.26 EKX43102.1 - 1.7e-05 24.8 0.0 3.6e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 WW domain dCache_1 PF02743.18 EKX43102.1 - 0.17 11.7 1.1 18 5.0 0.0 2.3 2 0 0 2 2 2 0 Cache domain Rhomboid_N PF12122.8 EKX43102.1 - 0.26 11.5 6.0 0.22 11.7 0.8 3.0 3 0 0 3 3 3 0 Cytoplasmic N-terminal domain of rhomboid serine protease DUF1484 PF07363.11 EKX43102.1 - 0.43 11.6 7.1 0.1 13.6 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1484) Zn_clus PF00172.18 EKX43104.1 - 4e-23 81.2 47.0 1.8e-08 34.4 9.4 3.3 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 EKX43105.1 - 2.9e-31 108.5 0.6 3.1e-21 75.7 0.0 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EKX43105.1 - 1.4e-20 73.8 0.8 1.6e-16 60.6 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX43105.1 - 7.1e-07 29.3 1.1 7.1e-07 29.3 1.1 1.6 2 1 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 EKX43105.1 - 0.0018 18.2 1.7 0.0019 18.1 0.6 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EKX43105.1 - 0.003 17.0 0.1 0.0071 15.8 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EKX43105.1 - 0.0061 16.0 0.0 0.018 14.4 0.0 1.7 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) ApbA PF02558.16 EKX43105.1 - 0.0068 16.1 0.1 0.014 15.1 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA RmlD_sub_bind PF04321.17 EKX43105.1 - 0.027 13.6 0.2 0.14 11.3 0.2 2.0 1 1 0 1 1 1 0 RmlD substrate binding domain DUF494 PF04361.13 EKX43105.1 - 0.039 13.9 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF494) 3HCDH_N PF02737.18 EKX43105.1 - 0.05 13.5 0.1 0.094 12.6 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FHA_2 PF17913.1 EKX43105.1 - 0.062 13.5 0.1 1.6 9.1 0.0 2.3 2 0 0 2 2 2 0 FHA domain SET PF00856.28 EKX43106.1 - 0.004 17.6 0.0 0.1 13.0 0.0 2.3 1 1 0 1 1 1 1 SET domain YdjM PF04307.14 EKX43106.1 - 0.16 11.2 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase Nop16 PF09420.10 EKX43107.1 - 9.1e-23 81.4 4.1 4e-15 56.4 0.3 2.1 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 Myb_DNA-binding PF00249.31 EKX43107.1 - 0.088 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain DnaJ PF00226.31 EKX43109.1 - 5e-15 55.4 0.0 1.7e-14 53.7 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain QSregVF_b PF12843.7 EKX43110.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor DNA_pol3_alpha PF07733.12 EKX43111.1 - 1.4e-29 103.5 0.0 2.3e-24 86.4 0.0 2.2 2 0 0 2 2 2 2 Bacterial DNA polymerase III alpha NTPase domain DNA_pol3_finger PF17657.1 EKX43111.1 - 9.6e-09 34.8 0.0 3.3e-08 33.1 0.0 1.7 1 1 1 2 2 2 1 Bacterial DNA polymerase III alpha subunit finger domain Apocytochr_F_N PF16639.5 EKX43111.1 - 0.0069 16.7 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 Apocytochrome F, N-terminal DEAD PF00270.29 EKX43112.1 - 3.6e-43 147.4 0.0 1e-42 145.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX43112.1 - 1.9e-27 95.8 0.0 1.5e-26 92.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain EMP70 PF02990.16 EKX43113.1 - 4.4e-190 632.8 5.6 4.4e-190 632.8 5.6 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 ABC2_membrane_2 PF12679.7 EKX43113.1 - 0.0013 18.1 3.3 0.0013 18.1 3.3 2.5 1 1 1 2 2 2 1 ABC-2 family transporter protein DUF31 PF01732.16 EKX43113.1 - 0.082 12.4 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Putative peptidase (DUF31) Asp PF00026.23 EKX43114.1 - 8.2e-34 117.4 0.0 1.2e-23 84.0 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EKX43114.1 - 4.5e-08 33.5 0.2 0.0013 19.0 0.0 2.3 2 0 0 2 2 2 2 Xylanase inhibitor N-terminal SAM_PNT PF02198.16 EKX43115.1 - 0.097 12.7 0.1 0.34 10.9 0.1 2.0 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain p450 PF00067.22 EKX43116.1 - 1.9e-60 204.9 0.0 3.6e-60 204.0 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Cullin_Nedd8 PF10557.9 EKX43116.1 - 0.096 12.7 0.4 0.23 11.5 0.4 1.6 1 0 0 1 1 1 0 Cullin protein neddylation domain PLAT PF01477.23 EKX43117.1 - 1.1e-63 213.1 0.3 6.5e-17 62.2 0.0 4.1 4 0 0 4 4 4 4 PLAT/LH2 domain ATS3 PF06232.11 EKX43117.1 - 1.6e-05 24.8 0.0 8.4 6.3 0.0 4.1 4 0 0 4 4 4 3 Embryo-specific protein 3, (ATS3) ATP-synt_B PF00430.18 EKX43117.1 - 0.37 10.9 5.3 0.089 12.9 1.9 1.6 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Keratin_2_head PF16208.5 EKX43120.1 - 0.021 15.0 1.3 0.021 15.0 1.3 3.3 4 0 0 4 4 4 0 Keratin type II head RRM_1 PF00076.22 EKX43120.1 - 0.032 14.1 0.0 0.62 9.9 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ion_trans_2 PF07885.16 EKX43121.1 - 6e-14 51.8 6.3 6e-14 51.8 6.3 3.1 2 1 1 3 3 3 1 Ion channel SK_channel PF03530.14 EKX43121.1 - 4.9e-11 42.6 0.8 4.9e-11 42.6 0.8 2.1 2 0 0 2 2 2 1 Calcium-activated SK potassium channel Ion_trans PF00520.31 EKX43121.1 - 5e-11 42.3 6.6 8.8e-11 41.5 6.5 1.7 1 1 0 1 1 1 1 Ion transport protein Lig_chan PF00060.26 EKX43121.1 - 0.00063 19.6 0.1 0.00063 19.6 0.1 1.8 2 0 0 2 2 2 1 Ligand-gated ion channel FAM76 PF16046.5 EKX43121.1 - 0.047 13.0 2.3 0.067 12.5 2.3 1.1 1 0 0 1 1 1 0 FAM76 protein DUF4381 PF14316.6 EKX43121.1 - 0.094 13.0 0.3 0.23 11.7 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) UPF0242 PF06785.11 EKX43121.1 - 6.4 6.8 8.7 0.72 9.9 2.1 2.4 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Zn_clus PF00172.18 EKX43123.1 - 9.6e-05 22.4 9.4 9.6e-05 22.4 9.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.7 EKX43124.1 - 1.7e-33 115.0 0.8 1.7e-07 31.7 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX43124.1 - 2.7e-30 104.4 0.1 2.5e-08 34.3 0.0 5.2 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX43124.1 - 1.5e-16 58.8 0.1 1 10.1 0.0 8.6 9 0 0 9 9 9 4 Ankyrin repeat Ank_5 PF13857.6 EKX43124.1 - 5.7e-12 45.6 8.3 0.18 12.2 0.0 7.7 3 3 5 8 8 8 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX43124.1 - 1.8e-09 37.6 0.1 0.66 10.5 0.0 7.1 8 0 0 8 8 8 2 Ankyrin repeat DUF5049 PF16468.5 EKX43124.1 - 0.0004 20.2 0.0 20 5.2 0.0 4.9 5 0 0 5 5 5 1 Domain of unknown function (DUF5049) BDHCT PF08072.11 EKX43124.1 - 0.62 10.2 7.8 1.1e+02 3.0 0.1 5.0 5 0 0 5 5 5 0 BDHCT (NUC031) domain PfkB PF00294.24 EKX43125.1 - 7.1e-34 117.5 0.1 9.7e-34 117.0 0.1 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EKX43125.1 - 0.0017 17.8 0.3 0.0032 16.9 0.3 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Glycos_transf_1 PF00534.20 EKX43126.1 - 2.4e-15 56.5 0.0 5.3e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EKX43126.1 - 6.8e-13 49.2 0.0 3.9e-12 46.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EKX43126.1 - 0.00058 20.3 0.0 0.0019 18.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 EKX43126.1 - 0.0018 18.3 0.0 0.0067 16.4 0.0 1.9 1 1 1 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 EKX43126.1 - 0.012 16.0 0.0 0.096 13.1 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferases group 1 PLA2G12 PF06951.11 EKX43127.1 - 2.3e-12 47.2 10.7 3.1e-12 46.8 10.7 1.2 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) TMEM138 PF14935.6 EKX43128.1 - 3.7e-12 46.9 6.7 7.3e-12 46.0 6.7 1.4 1 0 0 1 1 1 1 Transmembrane protein 138 SKA1 PF07160.12 EKX43128.1 - 7.9e-06 25.9 0.1 1e-05 25.5 0.1 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 UNC119_bdg PF15435.6 EKX43128.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 UNC119-binding protein C5orf30 homologue Helicase_C PF00271.31 EKX43129.1 - 4.3e-23 81.8 0.0 5.6e-20 71.7 0.0 2.3 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 EKX43129.1 - 8.3e-16 58.2 0.0 4.1e-15 56.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EKX43129.1 - 0.00027 21.0 0.0 0.00043 20.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ATP-synt_Z PF16594.5 EKX43129.1 - 0.2 11.2 0.0 0.5 9.9 0.0 1.6 1 0 0 1 1 1 0 Putative AtpZ or ATP-synthase-associated Phosphonate-bd PF12974.7 EKX43129.1 - 0.22 11.1 0.0 0.63 9.6 0.0 1.8 2 0 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Pkinase PF00069.25 EKX43130.1 - 1.1e-29 103.6 0.0 1.3e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX43130.1 - 2.9e-26 92.3 0.0 3.2e-26 92.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX43130.1 - 8.6e-05 21.5 0.0 0.00011 21.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX43130.1 - 0.0011 18.9 0.3 0.0035 17.3 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Ank_2 PF12796.7 EKX43131.1 - 6e-26 90.9 1.5 8.9e-13 48.6 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX43131.1 - 9.4e-19 67.5 5.0 9.7e-07 29.2 0.0 4.3 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EKX43131.1 - 3.4e-17 62.0 2.3 6.3e-05 23.2 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 EKX43131.1 - 5.7e-15 53.9 1.0 0.00025 21.2 0.0 5.7 6 1 1 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 EKX43131.1 - 2.3e-14 53.3 0.8 8.3e-05 22.8 0.1 3.6 2 2 2 4 4 4 3 Ankyrin repeats (many copies) DUF1843 PF08898.10 EKX43131.1 - 6.2e-07 29.8 1.2 0.013 16.0 0.3 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF1843) DUF3379 PF11859.8 EKX43131.1 - 0.0073 15.7 0.1 0.49 9.7 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3379) DUF249 PF03158.13 EKX43131.1 - 0.089 12.5 0.0 0.95 9.1 0.0 2.4 2 1 1 3 3 3 0 Multigene family 530 protein Metallophos_2 PF12850.7 EKX43133.1 - 4.9e-21 75.6 0.1 7.9e-21 74.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EKX43133.1 - 1.7e-06 28.7 0.9 1.4e-05 25.7 0.9 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PAP_fibrillin PF04755.12 EKX43135.1 - 1.8e-09 37.8 0.0 6.5e-09 36.0 0.0 1.7 1 1 0 1 1 1 1 PAP_fibrillin HTH_13 PF11972.8 EKX43135.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.6 1 1 0 1 1 1 0 HTH DNA binding domain DUF2353 PF09789.9 EKX43136.1 - 1.5 8.2 32.2 0.34 10.2 18.2 2.9 1 1 2 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) APG6_N PF17675.1 EKX43136.1 - 1.5 9.4 25.3 0.96 10.0 12.6 2.8 2 0 0 2 2 2 0 Apg6 coiled-coil region Endotoxin_C2 PF18449.1 EKX43136.1 - 2.2 8.7 10.3 0.64 10.4 2.8 2.8 3 0 0 3 3 3 0 Delta endotoxin Pkinase PF00069.25 EKX43137.1 - 0.00011 21.7 0.4 0.00022 20.7 0.4 1.5 1 1 0 1 1 1 1 Protein kinase domain Metallophos PF00149.28 EKX43140.1 - 1.1e-37 130.6 0.1 1.4e-37 130.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EKX43140.1 - 0.00077 19.8 0.6 0.002 18.5 0.6 1.7 1 1 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EKX43140.1 - 0.031 14.5 0.0 0.047 13.9 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain zf-RRN7 PF11781.8 EKX43140.1 - 0.09 12.5 1.3 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zinc_ribbon_5 PF13719.6 EKX43140.1 - 8.6 6.2 5.5 1.1 9.0 0.1 2.3 3 0 0 3 3 3 0 zinc-ribbon domain tRNA-synt_1b PF00579.25 EKX43143.1 - 1.8e-78 263.9 0.0 2.4e-77 260.2 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) WAP PF00095.21 EKX43144.1 - 0.036 14.5 2.9 0.11 13.0 2.9 1.8 1 0 0 1 1 1 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' GTP1_OBG PF01018.22 EKX43145.1 - 1.2e-44 151.7 4.8 1.6e-44 151.2 4.8 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 EKX43145.1 - 1.6e-24 86.2 0.0 2.7e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EKX43145.1 - 1e-07 31.6 0.0 2.3e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EKX43145.1 - 0.0014 18.2 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EKX43145.1 - 0.012 15.7 0.0 1.5 8.9 0.1 2.4 1 1 1 2 2 2 0 Dynamin family Gtr1_RagA PF04670.12 EKX43145.1 - 0.031 13.6 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EKX43145.1 - 0.032 14.0 0.0 0.098 12.4 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 EKX43145.1 - 0.14 11.7 0.0 7.4 6.1 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 EKX43145.1 - 0.16 12.5 0.0 0.39 11.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 EKX43145.1 - 0.17 12.1 0.0 1.7 8.9 0.0 2.2 1 1 1 2 2 2 0 AAA domain ADH_zinc_N PF00107.26 EKX43146.1 - 0.0021 18.0 0.0 0.0042 17.1 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase CRAL_TRIO PF00650.20 EKX43147.1 - 1.3e-22 80.2 0.2 2e-22 79.6 0.2 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EKX43147.1 - 0.014 15.5 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain NYD-SP28 PF14772.6 EKX43148.1 - 1.9e-22 79.2 15.5 1.9e-22 79.2 15.5 5.1 2 1 3 6 6 6 1 Sperm tail NYD-SP28_assoc PF14775.6 EKX43148.1 - 3.8e-11 42.9 0.6 3.8e-11 42.9 0.6 3.9 3 0 0 3 3 3 1 Sperm tail C-terminal domain DUF664 PF04978.12 EKX43148.1 - 0.24 11.8 8.4 0.11 12.9 1.1 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF664) PqqD PF05402.12 EKX43148.1 - 0.25 11.7 1.8 0.44 10.9 0.1 2.4 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) HrpA_pilin PF09589.10 EKX43148.1 - 0.63 10.8 4.3 2.3 9.0 0.5 2.8 2 0 0 2 2 2 0 HrpA pilus formation protein DUF725 PF05267.12 EKX43148.1 - 9.6 6.2 11.1 1.2 9.2 0.3 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF725) DnaJ PF00226.31 EKX43149.1 - 8.7e-16 57.8 0.4 8.7e-16 57.8 0.4 2.5 2 0 0 2 2 2 1 DnaJ domain Myb_DNA-binding PF00249.31 EKX43149.1 - 7.8e-15 54.8 5.4 3.7e-07 30.2 0.6 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX43149.1 - 5.5e-08 32.9 4.0 0.00099 19.3 0.1 3.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain RRN3 PF05327.11 EKX43149.1 - 0.27 9.7 8.5 0.64 8.5 8.5 1.7 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2387 PF09526.10 EKX43149.1 - 0.94 9.7 7.1 16 5.8 3.8 3.0 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) IFT57 PF10498.9 EKX43150.1 - 5.2e-111 371.1 7.7 6.4e-111 370.8 7.7 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Syntaxin_2 PF14523.6 EKX43150.1 - 0.00014 22.2 13.0 0.0026 18.1 4.0 2.2 2 0 0 2 2 2 2 Syntaxin-like protein Spc7 PF08317.11 EKX43150.1 - 0.00023 20.2 13.8 0.00033 19.6 13.8 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein YtxH PF12732.7 EKX43150.1 - 0.0017 18.8 2.8 1.8 9.1 2.8 2.8 1 1 0 1 1 1 1 YtxH-like protein Occludin_ELL PF07303.13 EKX43150.1 - 0.0019 18.9 9.6 0.0037 18.0 8.9 2.0 1 1 0 1 1 1 1 Occludin homology domain LRRFIP PF09738.9 EKX43150.1 - 0.0029 17.2 12.4 0.0029 17.2 12.4 1.8 1 1 1 2 2 2 1 LRRFIP family GAS PF13851.6 EKX43150.1 - 0.0063 15.9 15.1 0.0063 15.9 15.1 2.0 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding TMPIT PF07851.13 EKX43150.1 - 0.0085 15.4 15.0 0.013 14.8 9.3 2.1 1 1 1 2 2 2 1 TMPIT-like protein Sec2p PF06428.11 EKX43150.1 - 0.0088 16.0 10.0 0.0088 16.0 10.0 2.4 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p Seryl_tRNA_N PF02403.22 EKX43150.1 - 0.011 16.0 14.7 0.024 14.9 1.9 2.9 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 EKX43150.1 - 0.011 15.8 14.1 0.031 14.3 6.8 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EKX43150.1 - 0.017 15.2 6.3 0.081 13.0 5.8 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 EKX43150.1 - 0.018 14.6 7.7 0.025 14.2 7.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit SpecificRecomb PF10136.9 EKX43150.1 - 0.029 12.7 4.1 0.038 12.3 4.1 1.1 1 0 0 1 1 1 0 Site-specific recombinase YkyA PF10368.9 EKX43150.1 - 0.034 13.8 24.6 0.025 14.3 7.0 3.1 1 1 1 3 3 3 0 Putative cell-wall binding lipoprotein HalX PF08663.10 EKX43150.1 - 0.034 14.5 4.8 0.78 10.1 4.4 2.8 1 1 1 2 2 2 0 HalX domain EspB PF05802.11 EKX43150.1 - 0.039 14.0 4.5 0.075 13.0 4.5 1.4 1 0 0 1 1 1 0 Enterobacterial EspB protein Laminin_II PF06009.12 EKX43150.1 - 0.042 13.9 18.9 0.61 10.1 8.5 4.0 1 1 3 4 4 4 0 Laminin Domain II DUF4407 PF14362.6 EKX43150.1 - 0.052 12.9 9.2 0.095 12.0 9.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 EKX43150.1 - 0.071 13.4 8.4 0.23 11.8 2.2 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TPR_MLP1_2 PF07926.12 EKX43150.1 - 0.082 13.0 21.0 6.6 6.8 15.4 3.5 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Cir_Bir_Yir PF06022.11 EKX43150.1 - 0.088 12.3 3.6 0.13 11.7 3.6 1.2 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir HAD_2 PF13419.6 EKX43150.1 - 0.11 12.6 3.5 0.21 11.7 3.5 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hemagglutinin PF00509.18 EKX43150.1 - 0.13 10.7 3.3 0.2 10.0 3.3 1.3 1 0 0 1 1 1 0 Haemagglutinin FapA PF03961.13 EKX43150.1 - 0.13 10.8 15.4 2.3 6.7 15.2 2.2 1 1 0 1 1 1 0 Flagellar Assembly Protein A AAA_13 PF13166.6 EKX43150.1 - 0.18 10.4 14.2 0.21 10.2 12.3 1.4 1 1 0 1 1 1 0 AAA domain DUF3450 PF11932.8 EKX43150.1 - 0.21 10.9 11.6 0.072 12.4 9.0 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF3450) T3SSipB PF16535.5 EKX43150.1 - 0.23 12.0 3.7 0.54 10.7 3.7 1.6 1 1 0 1 1 1 0 Type III cell invasion protein SipB DUF1043 PF06295.12 EKX43150.1 - 0.23 11.5 11.4 1.2 9.1 5.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) Prefoldin PF02996.17 EKX43150.1 - 0.26 11.2 14.7 0.067 13.1 2.9 3.4 2 1 1 3 3 3 0 Prefoldin subunit DUF4200 PF13863.6 EKX43150.1 - 0.29 11.5 16.2 0.048 14.1 9.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) WXG100 PF06013.12 EKX43150.1 - 0.29 11.4 4.8 0.46 10.8 3.3 2.3 2 1 0 2 2 1 0 Proteins of 100 residues with WXG DUF3552 PF12072.8 EKX43150.1 - 0.3 10.5 18.2 1.9 7.9 7.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF745 PF05335.13 EKX43150.1 - 0.32 10.7 6.5 0.56 9.9 6.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) MCPsignal PF00015.21 EKX43150.1 - 0.43 10.4 6.2 1.3 8.8 4.0 2.3 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain COG2 PF06148.11 EKX43150.1 - 0.43 10.7 10.5 0.81 9.8 1.4 2.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4600 PF15372.6 EKX43150.1 - 0.45 11.0 20.4 0.12 12.9 12.8 2.6 2 1 1 3 3 2 0 Domain of unknown function (DUF4600) KxDL PF10241.9 EKX43150.1 - 0.5 10.7 14.8 0.26 11.6 8.0 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein NPV_P10 PF05531.12 EKX43150.1 - 0.7 10.4 8.2 4.5 7.8 5.8 3.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 EKX43150.1 - 0.74 10.1 12.2 0.58 10.5 8.6 2.4 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LOH1CR12 PF10158.9 EKX43150.1 - 0.79 9.8 5.8 2.5 8.1 4.6 2.3 2 1 0 2 2 2 0 Tumour suppressor protein Prominin PF05478.11 EKX43150.1 - 0.92 7.4 7.6 1.4 6.8 7.6 1.3 1 0 0 1 1 1 0 Prominin Sec34 PF04136.15 EKX43150.1 - 1.1 9.2 12.0 0.53 10.2 4.0 2.5 1 1 1 2 2 2 0 Sec34-like family Tweety PF04906.13 EKX43150.1 - 1.1 7.9 3.4 1.7 7.2 3.4 1.4 1 0 0 1 1 1 0 Tweety FAM76 PF16046.5 EKX43150.1 - 1.3 8.3 22.5 0.3 10.4 12.0 2.2 1 1 1 2 2 2 0 FAM76 protein DUF3053 PF11254.8 EKX43150.1 - 1.3 8.5 8.0 2.9 7.4 6.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) Ferritin PF00210.24 EKX43150.1 - 1.4 8.9 7.5 0.41 10.6 0.8 3.1 3 1 0 3 3 2 0 Ferritin-like domain FUSC-like PF12805.7 EKX43150.1 - 1.6 7.7 3.7 2.3 7.2 3.7 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS OmpH PF03938.14 EKX43150.1 - 2.2 8.6 16.5 17 5.8 15.8 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) RmuC PF02646.16 EKX43150.1 - 2.2 7.3 17.2 0.69 9.0 5.8 3.1 2 1 1 3 3 3 0 RmuC family Jnk-SapK_ap_N PF09744.9 EKX43150.1 - 2.5 8.3 23.3 0.75 10.0 7.9 2.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 YlqD PF11068.8 EKX43150.1 - 2.6 8.4 17.0 0.41 11.0 11.2 2.3 1 1 1 2 2 2 0 YlqD protein YojJ PF10372.9 EKX43150.1 - 2.7 8.2 11.2 16 5.7 3.2 3.5 2 2 2 4 4 4 0 Bacterial membrane-spanning protein N-terminus ABC_tran_CTD PF16326.5 EKX43150.1 - 2.9 8.2 11.8 2.2 8.6 3.0 3.2 1 1 1 2 2 2 0 ABC transporter C-terminal domain Allexi_40kDa PF05549.11 EKX43150.1 - 3.1 7.2 10.3 3.8 6.9 1.2 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein CENP-H PF05837.12 EKX43150.1 - 4.1 7.8 17.6 0.16 12.4 9.0 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF16 PF01519.16 EKX43150.1 - 6.3 7.3 16.0 73 3.9 9.2 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 Atg14 PF10186.9 EKX43150.1 - 6.7 5.7 13.8 11 5.0 13.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 EKX43150.1 - 8.7 6.5 16.2 7.1 6.8 7.2 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Bromodomain PF00439.25 EKX43151.1 - 7.8e-24 83.6 0.0 9.3e-24 83.3 0.0 1.1 1 0 0 1 1 1 1 Bromodomain PDCD2_C PF04194.13 EKX43152.1 - 5.9e-39 133.9 1.4 8.8e-39 133.4 0.1 1.8 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain PhnA_Zn_Ribbon PF08274.12 EKX43152.1 - 0.035 14.1 0.1 0.081 12.9 0.1 1.5 1 0 0 1 1 1 0 PhnA Zinc-Ribbon Zn_Tnp_IS1595 PF12760.7 EKX43152.1 - 0.056 13.4 2.8 0.15 12.0 2.8 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Lar_restr_allev PF14354.6 EKX43152.1 - 0.082 13.3 0.9 0.27 11.7 0.9 1.9 1 1 0 1 1 1 0 Restriction alleviation protein Lar PGM_PMM_I PF02878.16 EKX43153.1 - 2.5e-16 59.6 0.0 1.6e-07 31.1 0.0 3.5 3 0 0 3 3 3 3 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 EKX43153.1 - 1.8e-10 40.8 0.7 5.9e-10 39.2 0.5 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 EKX43153.1 - 5.5e-06 26.9 0.1 2.9e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Collagen PF01391.18 EKX43155.1 - 5.1e-06 26.2 18.3 5.4e-06 26.1 14.6 2.1 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) SlyX PF04102.12 EKX43155.1 - 0.32 11.7 2.8 6 7.6 0.3 2.6 2 0 0 2 2 2 0 SlyX KxDL PF10241.9 EKX43155.1 - 2.4 8.5 0.0 2.4 8.5 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein HrpB7 PF09486.10 EKX43155.1 - 4.5 7.6 7.7 0.24 11.8 2.3 1.6 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) PRK PF00485.18 EKX43156.1 - 2.1e-40 138.6 0.1 3.2e-40 138.0 0.1 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 EKX43156.1 - 7.4e-07 28.6 0.0 2.2e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 EKX43156.1 - 0.00023 21.7 0.1 0.00053 20.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain CoaE PF01121.20 EKX43156.1 - 0.00026 20.7 3.9 0.0041 16.8 3.9 2.2 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_16 PF13191.6 EKX43156.1 - 0.00049 20.5 0.0 0.00098 19.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Torsin PF06309.11 EKX43156.1 - 0.0005 20.2 0.0 0.0025 17.9 0.0 2.2 1 1 0 1 1 1 1 Torsin MobB PF03205.14 EKX43156.1 - 0.0021 17.9 0.0 0.0064 16.4 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.27 EKX43156.1 - 0.0021 18.6 0.0 0.0043 17.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_33 PF13671.6 EKX43156.1 - 0.0036 17.5 0.0 0.0064 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 EKX43156.1 - 0.004 16.7 0.1 0.013 15.1 0.1 1.8 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 EKX43156.1 - 0.0049 17.2 0.0 0.0094 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EKX43156.1 - 0.0058 16.4 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EKX43156.1 - 0.0061 16.3 0.1 0.013 15.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MeaB PF03308.16 EKX43156.1 - 0.011 14.8 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 EKX43156.1 - 0.011 16.2 1.2 0.089 13.2 1.2 2.3 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EKX43156.1 - 0.033 14.1 0.3 0.066 13.1 0.3 1.5 1 0 0 1 1 1 0 NTPase DUF87 PF01935.17 EKX43156.1 - 0.035 14.2 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_23 PF13476.6 EKX43156.1 - 0.036 14.5 0.0 0.064 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EKX43156.1 - 0.04 13.1 0.1 0.068 12.4 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain T2SSE PF00437.20 EKX43156.1 - 0.058 12.4 0.0 0.13 11.3 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein RNA_helicase PF00910.22 EKX43156.1 - 0.098 13.0 0.0 1.1 9.7 0.0 2.2 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 EKX43156.1 - 0.1 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Cytidylate_kin PF02224.18 EKX43156.1 - 0.13 12.0 0.2 5.7 6.6 0.2 2.2 1 1 0 1 1 1 0 Cytidylate kinase SMC_N PF02463.19 EKX43156.1 - 0.16 11.4 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Aa_trans PF01490.18 EKX43158.1 - 5.7e-24 84.6 0.7 6.4e-24 84.4 0.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 EKX43159.1 - 1.9e-16 59.8 6.2 2.3e-16 59.5 6.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EKX43159.1 - 6.6e-06 25.4 1.1 7.9e-06 25.2 1.1 1.1 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family SAP PF02037.27 EKX43160.1 - 0.00068 19.3 0.1 1.1 9.1 0.0 2.5 2 0 0 2 2 2 2 SAP domain BRCT PF00533.26 EKX43160.1 - 0.01 16.2 0.4 0.54 10.7 0.1 2.5 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Rho_N PF07498.12 EKX43160.1 - 0.016 15.1 0.2 8.8 6.4 0.0 2.9 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain LETM1 PF07766.13 EKX43160.1 - 0.35 10.2 8.1 0.33 10.3 0.1 3.0 3 0 0 3 3 3 0 LETM1-like protein SSP160 PF06933.11 EKX43160.1 - 1.7 6.8 13.2 2.5 6.2 13.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DGF-1_C PF11040.8 EKX43163.1 - 0.078 13.0 6.9 2.9 8.0 1.2 3.4 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF2694 PF10904.8 EKX43163.1 - 0.16 12.1 0.5 31 4.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2694) KxDL PF10241.9 EKX43163.1 - 0.71 10.2 9.8 4.1 7.7 0.1 4.4 3 1 0 3 3 3 0 Uncharacterized conserved protein Tnp_22_trimer PF17489.2 EKX43163.1 - 0.89 9.6 11.1 5 7.2 1.0 3.6 3 0 0 3 3 3 0 L1 transposable element trimerization domain DUF4346 PF14251.6 EKX43163.1 - 3.7 7.6 6.3 12 5.9 0.2 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4346) Mst1_SARAH PF11629.8 EKX43163.1 - 4.6 7.4 12.8 17 5.6 0.2 4.9 4 0 0 4 4 4 0 C terminal SARAH domain of Mst1 Lzipper-MIP1 PF14389.6 EKX43164.1 - 0.0022 18.2 0.3 0.01 16.1 0.1 2.3 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 Sipho_Gp157 PF05565.11 EKX43164.1 - 0.035 14.1 0.1 3.1 7.8 0.0 2.2 1 1 1 2 2 2 0 Siphovirus Gp157 Enkurin PF13864.6 EKX43164.1 - 0.045 14.2 1.2 0.076 13.5 0.2 1.9 2 0 0 2 2 2 0 Calmodulin-binding CCDC144C PF14915.6 EKX43164.1 - 0.049 12.8 7.8 0.28 10.2 4.6 2.8 2 1 0 2 2 2 0 CCDC144C protein coiled-coil region DUF5395 PF17373.2 EKX43164.1 - 0.15 12.7 0.4 3.3 8.4 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5395) DUF2046 PF09755.9 EKX43164.1 - 0.63 9.2 6.3 3.6 6.7 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein H4 (DUF2046) Mto2_bdg PF12808.7 EKX43164.1 - 5.6 7.4 9.7 2.6 8.4 0.6 3.4 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region PP-binding PF00550.25 EKX43165.1 - 2.4e-12 47.0 0.2 3.2e-12 46.6 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EKX43165.1 - 0.00046 20.4 0.3 0.00055 20.1 0.3 1.2 1 0 0 1 1 1 1 Acyl-carrier Ribosomal_L50 PF10501.9 EKX43165.1 - 0.014 15.5 0.1 0.056 13.6 0.1 2.0 1 1 0 1 1 1 0 Ribosomal subunit 39S PipA PF07108.11 EKX43166.1 - 0.0011 18.6 0.1 0.0018 17.8 0.1 1.4 1 0 0 1 1 1 1 PipA protein UAA PF08449.11 EKX43167.1 - 5.5e-38 130.9 1.7 6.7e-38 130.6 1.7 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 EKX43167.1 - 6.6e-05 22.4 3.1 7.6e-05 22.2 3.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 EKX43167.1 - 0.0034 16.6 2.7 0.029 13.5 0.2 2.4 2 1 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.20 EKX43167.1 - 0.0063 16.7 11.4 0.007 16.5 9.9 1.9 2 1 1 3 3 3 1 EamA-like transporter family SLATT_6 PF18169.1 EKX43167.1 - 0.014 15.0 1.2 0.56 9.8 0.3 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 Cupin_8 PF13621.6 EKX43168.1 - 8e-23 81.5 0.2 1e-22 81.1 0.2 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EKX43168.1 - 2.7e-08 33.6 0.0 2.9e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 EKX43168.1 - 3.5e-08 33.9 0.0 6.3e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_1 PF00190.22 EKX43168.1 - 0.073 12.7 0.0 0.096 12.3 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_2 PF07883.11 EKX43168.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Cupin domain EMP70 PF02990.16 EKX43169.1 - 3.1e-194 646.5 13.8 3.1e-194 646.5 13.8 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 CrgA PF06781.12 EKX43169.1 - 1.1 9.3 4.2 0.99 9.5 0.1 2.7 3 0 0 3 3 3 0 Cell division protein CrgA Cation_efflux PF01545.21 EKX43172.1 - 2e-41 142.0 11.2 3.1e-41 141.3 11.2 1.3 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EKX43172.1 - 0.14 12.3 2.9 0.27 11.4 2.9 1.4 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter DUF4349 PF14257.6 EKX43172.1 - 1.8 7.9 6.9 0.19 11.2 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4349) Guanylate_kin PF00625.21 EKX43173.1 - 2.7e-26 92.4 0.0 3e-26 92.2 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase Xylo_C PF12529.8 EKX43173.1 - 0.077 12.6 0.0 0.099 12.2 0.0 1.1 1 0 0 1 1 1 0 Xylosyltransferase C terminal SET PF00856.28 EKX43175.1 - 1.3e-06 28.9 0.0 1.3e-06 28.9 0.0 1.1 1 0 0 1 1 1 1 SET domain Gly_transf_sug PF04488.15 EKX43177.1 - 4.7e-09 36.8 0.0 8.3e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 EKX43177.1 - 8.4e-07 28.6 1.5 0.00095 18.6 0.0 2.1 1 1 1 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.12 EKX43177.1 - 0.0021 17.5 0.1 0.0042 16.5 0.0 1.7 2 1 0 2 2 2 1 Capsular polysaccharide synthesis protein PDZ_2 PF13180.6 EKX43178.1 - 1.6e-05 25.1 0.0 2.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX43178.1 - 3.2e-05 24.2 0.0 5.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX43178.1 - 0.00016 21.4 0.0 0.00027 20.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX43178.1 - 0.054 13.5 0.0 0.08 12.9 0.0 1.2 1 0 0 1 1 1 0 Tricorn protease PDZ domain TPR_17 PF13431.6 EKX43179.1 - 3.1e-21 74.2 2.5 0.00019 21.5 0.5 6.5 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EKX43179.1 - 1.7e-20 71.4 6.2 6.6e-06 25.9 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 EKX43179.1 - 2.3e-20 71.5 4.3 6.6e-05 22.6 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat DUF1736 PF08409.11 EKX43179.1 - 5.4e-18 64.8 1.1 1.4e-17 63.4 1.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_8 PF13181.6 EKX43179.1 - 8.9e-17 59.8 0.1 0.06 13.6 0.0 5.9 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_11 PF13414.6 EKX43179.1 - 1e-15 57.1 9.0 7.7e-05 22.3 0.0 6.4 4 2 4 8 8 7 4 TPR repeat TPR_19 PF14559.6 EKX43179.1 - 7.2e-14 52.0 0.0 0.00032 21.2 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX43179.1 - 7.3e-14 52.1 2.2 0.042 14.5 0.2 5.1 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 EKX43179.1 - 1e-13 51.3 3.1 0.0011 19.2 0.0 4.6 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX43179.1 - 3.7e-12 46.0 1.0 0.6 11.1 0.0 6.1 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 EKX43179.1 - 2.8e-07 30.7 1.5 0.014 16.0 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX43179.1 - 2.1e-06 27.4 3.4 0.072 13.1 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX43179.1 - 1.2e-05 25.0 9.3 0.29 11.1 0.4 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 EKX43179.1 - 0.00016 22.0 0.3 9.4 7.2 0.1 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX43179.1 - 0.00024 21.3 0.1 0.11 12.7 0.0 3.4 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 EKX43179.1 - 0.011 16.0 1.5 20 5.6 0.2 4.2 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EKX43179.1 - 0.026 14.7 0.3 3.2 8.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Amj PF10997.8 EKX43179.1 - 0.033 13.5 0.2 0.059 12.7 0.2 1.3 1 0 0 1 1 1 0 Alternate to MurJ BTAD PF03704.17 EKX43179.1 - 0.035 14.5 0.0 0.22 12.0 0.0 2.3 1 1 1 2 2 2 0 Bacterial transcriptional activator domain EMP70 PF02990.16 EKX43179.1 - 0.34 9.5 3.7 13 4.3 2.6 2.2 2 0 0 2 2 2 0 Endomembrane protein 70 NARP1 PF12569.8 EKX43179.1 - 1.4 7.8 3.9 11 4.8 0.0 3.0 3 1 0 3 3 3 0 NMDA receptor-regulated protein 1 DNA_pol_phi PF04931.13 EKX43179.1 - 2.5 6.1 4.3 3.9 5.5 4.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF3367 PF11847.8 EKX43180.1 - 0.28 9.0 0.9 0.37 8.6 0.9 1.1 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase Strabismus PF06638.11 EKX43180.1 - 0.35 9.5 8.8 0.51 8.9 8.8 1.3 1 0 0 1 1 1 0 Strabismus protein CDV3 PF15359.6 EKX43180.1 - 0.87 10.1 9.5 0.43 11.1 6.7 2.1 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 zinc_ribbon_6 PF14599.6 EKX43181.1 - 5.5e-21 74.3 0.1 5.5e-21 74.3 0.1 3.8 4 1 0 4 4 4 1 Zinc-ribbon zf-CHY PF05495.12 EKX43181.1 - 7.6e-17 61.6 18.5 7.6e-17 61.6 18.5 3.5 1 1 1 3 3 3 2 CHY zinc finger zf-RING_2 PF13639.6 EKX43181.1 - 3.6e-09 36.8 8.2 3.6e-09 36.8 8.2 5.2 4 1 0 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 EKX43181.1 - 2.1e-06 27.7 2.3 2.1e-06 27.7 2.3 4.4 5 2 1 6 6 6 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EKX43181.1 - 3.6e-05 23.5 8.0 3.6e-05 23.5 8.0 5.1 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EKX43181.1 - 4.4e-05 23.1 2.1 4.4e-05 23.1 2.1 4.0 3 1 1 4 4 4 2 RING-like zinc finger GrpE PF01025.19 EKX43182.1 - 0.028 14.1 1.8 0.054 13.1 1.8 1.4 1 0 0 1 1 1 0 GrpE CENP-F_leu_zip PF10473.9 EKX43182.1 - 0.044 13.8 3.3 0.1 12.6 3.3 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Copper-fist PF00649.18 EKX43182.1 - 0.15 11.5 6.5 0.074 12.6 2.9 2.1 2 0 0 2 2 2 0 Copper fist DNA binding domain ZapB PF06005.12 EKX43182.1 - 1.1 9.8 5.3 2 8.9 4.2 2.0 1 1 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 EKX43182.1 - 2 8.2 8.8 2.2 8.1 6.1 2.1 1 1 1 2 2 2 0 Septum formation initiator Pkinase PF00069.25 EKX43183.1 - 1.9e-14 53.7 0.0 2.1e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX43183.1 - 0.00032 20.1 0.0 0.00038 19.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX43183.1 - 0.01 15.8 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EKX43183.1 - 0.1 11.9 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EKX43183.1 - 0.19 10.5 0.0 0.2 10.4 0.0 1.0 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 EKX43183.1 - 0.21 10.5 0.0 0.23 10.4 0.0 1.0 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase CRAL_TRIO PF00650.20 EKX43185.1 - 0.00043 20.0 0.2 0.054 13.2 0.0 2.5 1 1 1 2 2 2 2 CRAL/TRIO domain SET PF00856.28 EKX43186.1 - 0.00011 22.6 0.0 0.00016 22.1 0.0 1.3 1 0 0 1 1 1 1 SET domain G6PD_C PF02781.16 EKX43186.1 - 0.16 11.1 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, C-terminal domain Tcp11 PF05794.13 EKX43187.1 - 1.3e-17 64.1 0.5 2.8e-17 62.9 0.5 1.5 1 0 0 1 1 1 1 T-complex protein 11 ubiquitin PF00240.23 EKX43187.1 - 0.0023 17.7 0.2 0.0023 17.7 0.2 2.2 3 0 0 3 3 3 1 Ubiquitin family Rad60-SLD PF11976.8 EKX43187.1 - 0.0094 15.8 0.2 0.023 14.5 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like KBP_C PF12309.8 EKX43187.1 - 0.13 11.7 0.7 0.22 11.0 0.1 1.6 2 0 0 2 2 2 0 KIF-1 binding protein C terminal DUF4407 PF14362.6 EKX43188.1 - 0.11 11.8 3.3 0.32 10.3 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ICAT PF06384.11 EKX43188.1 - 0.15 12.3 1.7 0.44 10.8 1.7 1.8 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT NOA36 PF06524.12 EKX43188.1 - 1.3 8.3 10.6 0.026 13.8 2.4 2.2 2 0 0 2 2 2 0 NOA36 protein CDH1_2_SANT_HL1 PF18375.1 EKX43188.1 - 3 8.6 5.8 0.76 10.5 1.8 2.1 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 PhoU PF01895.19 EKX43188.1 - 5.3 7.6 8.8 6.5 7.3 1.2 2.5 2 0 0 2 2 2 0 PhoU domain TPH PF13868.6 EKX43189.1 - 0.0051 15.4 39.2 0.0051 15.4 39.2 2.2 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Pkinase PF00069.25 EKX43191.1 - 1.2e-45 156.0 0.0 1.3e-45 155.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX43191.1 - 2.5e-43 148.2 0.0 3e-43 148.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX43191.1 - 0.00028 20.3 0.0 0.00039 19.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EKX43191.1 - 0.0011 18.1 0.1 0.0012 17.9 0.1 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EKX43191.1 - 0.0014 17.5 0.0 0.0018 17.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EKX43191.1 - 0.0086 15.7 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EKX43191.1 - 0.0099 15.8 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX43191.1 - 0.019 14.3 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SH3_15 PF18346.1 EKX43193.1 - 0.051 13.9 0.1 0.14 12.5 0.1 1.8 1 0 0 1 1 1 0 Mind bomb SH3 repeat domain SH3_1 PF00018.28 EKX43193.1 - 0.12 12.0 0.1 0.33 10.6 0.1 1.8 1 0 0 1 1 1 0 SH3 domain Glyco_trans_1_2 PF13524.6 EKX43193.1 - 1.4 9.4 3.5 23 5.5 0.2 2.9 2 0 0 2 2 2 0 Glycosyl transferases group 1 ABC_tran_CTD PF16326.5 EKX43193.1 - 3 8.2 13.9 0.27 11.5 4.6 3.2 2 1 1 3 3 3 0 ABC transporter C-terminal domain YabA PF06156.13 EKX43194.1 - 0.0058 17.2 2.5 0.0058 17.2 2.5 4.2 2 1 2 4 4 4 1 Initiation control protein YabA HAP1_N PF04849.13 EKX43194.1 - 0.017 14.4 0.4 0.017 14.4 0.4 2.9 2 1 0 2 2 2 0 HAP1 N-terminal conserved region MAD PF05557.13 EKX43194.1 - 0.11 10.8 47.7 0.15 10.4 47.7 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Peptidase_C10 PF01640.17 EKX43194.1 - 0.4 11.0 3.3 0.4 11.0 2.1 1.6 1 1 0 1 1 1 0 Peptidase C10 family Tropomyosin PF00261.20 EKX43194.1 - 1.9 7.8 53.0 0.25 10.7 33.2 2.7 1 1 0 2 2 2 0 Tropomyosin Alanine_zipper PF11839.8 EKX43194.1 - 2.3 8.6 10.1 0.064 13.6 2.3 2.5 3 0 0 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein TPT PF03151.16 EKX43195.1 - 5.5e-82 275.4 19.3 6.5e-82 275.1 19.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EKX43195.1 - 0.00023 21.3 31.2 0.038 14.2 11.9 2.3 2 0 0 2 2 2 2 EamA-like transporter family zf-MYND PF01753.18 EKX43196.1 - 4e-12 46.0 17.2 4e-12 46.0 17.2 3.4 2 1 1 3 3 3 1 MYND finger DUF1356 PF07092.12 EKX43196.1 - 0.0011 18.3 0.4 0.0017 17.6 0.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1356) RNA_POL_M_15KD PF02150.16 EKX43196.1 - 1.3 9.0 0.1 1.3 9.0 0.1 5.0 3 2 0 3 3 3 0 RNA polymerases M/15 Kd subunit Pkinase_Tyr PF07714.17 EKX43197.1 - 1.4e-43 149.1 0.0 1.6e-43 148.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX43197.1 - 9.9e-43 146.4 0.0 1.2e-42 146.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EKX43197.1 - 5.5e-05 22.1 0.2 5.6e-05 22.1 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EKX43197.1 - 0.00085 18.7 0.2 0.0013 18.1 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX43197.1 - 0.033 14.1 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Stn1_C PF12659.7 EKX43197.1 - 0.076 13.0 0.1 0.8 9.7 0.0 2.1 2 0 0 2 2 2 0 Telomere capping C-terminal wHTH Kinase-like PF14531.6 EKX43197.1 - 0.16 11.3 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like LRR_8 PF13855.6 EKX43198.1 - 4.3e-62 205.8 45.1 8e-14 51.1 0.9 7.1 2 2 5 7 7 7 7 Leucine rich repeat LRR_5 PF13306.6 EKX43198.1 - 5.7e-26 91.0 0.0 3.1e-08 33.6 0.0 3.5 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 EKX43198.1 - 6.7e-26 89.9 54.4 3.2e-05 24.2 1.8 7.5 2 1 8 10 10 10 10 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX43198.1 - 4.6e-09 36.0 7.9 0.14 11.7 0.1 5.0 1 1 5 6 6 6 5 Leucine-rich repeat LRR_1 PF00560.33 EKX43198.1 - 1.2e-07 31.2 47.8 0.23 12.1 0.4 11.7 13 0 0 13 13 13 4 Leucine Rich Repeat DUF1391 PF07151.12 EKX43198.1 - 0.091 12.6 0.2 7.5 6.5 0.0 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1391) Glyco_transf_8 PF01501.20 EKX43199.1 - 8.2e-14 51.8 1.0 8.9e-13 48.4 1.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EKX43199.1 - 0.00061 19.2 0.1 0.0009 18.7 0.1 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.16 EKX43199.1 - 0.0015 18.6 0.1 0.0022 18.0 0.1 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF1317 PF07026.11 EKX43199.1 - 0.046 13.5 0.0 15 5.5 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1317) Glyco_transf_24 PF18404.1 EKX43199.1 - 0.048 13.1 0.2 0.068 12.6 0.2 1.2 1 0 0 1 1 1 0 Glucosyltransferase 24 Filamin PF00630.19 EKX43199.1 - 0.089 13.6 0.0 0.2 12.5 0.0 1.6 1 0 0 1 1 1 0 Filamin/ABP280 repeat Bd3614-deam PF14439.6 EKX43199.1 - 0.52 10.4 2.5 0.92 9.6 2.5 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase CENP-B_dimeris PF09026.10 EKX43199.1 - 0.63 10.5 8.4 1.2 9.5 8.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NAD_binding_10 PF13460.6 EKX43200.1 - 3.3e-31 108.6 0.0 4.2e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EKX43200.1 - 3.4e-12 46.4 0.0 5.4e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EKX43200.1 - 2.8e-10 40.1 0.0 8.1e-10 38.6 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EKX43200.1 - 5.9e-08 32.0 0.0 8.8e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 EKX43200.1 - 7.1e-06 26.3 0.1 1.5e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain GDP_Man_Dehyd PF16363.5 EKX43200.1 - 1.5e-05 24.6 0.0 2.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 EKX43200.1 - 0.00011 22.1 0.0 0.00022 21.2 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EKX43200.1 - 0.00031 20.3 0.2 0.0005 19.6 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Shikimate_DH PF01488.20 EKX43200.1 - 0.00068 19.7 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EKX43200.1 - 0.0028 17.9 0.0 0.0047 17.2 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 EKX43200.1 - 0.0038 17.3 0.4 0.008 16.3 0.4 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 EKX43200.1 - 0.011 14.9 0.1 0.04 13.1 0.1 1.8 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EKX43200.1 - 0.035 13.2 0.0 0.062 12.4 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_4 PF07993.12 EKX43200.1 - 0.049 12.8 0.0 0.12 11.5 0.0 1.6 2 0 0 2 2 2 0 Male sterility protein adh_short_C2 PF13561.6 EKX43200.1 - 0.072 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase 2-Hacid_dh_C PF02826.19 EKX43200.1 - 0.13 11.6 0.1 0.39 10.0 0.1 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CPP1-like PF11833.8 EKX43201.1 - 3.8 7.1 7.1 1 9.0 3.3 1.9 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF2157 PF09925.9 EKX43201.1 - 8.1 6.2 10.9 2.4 8.0 6.6 2.3 2 1 1 3 3 3 0 Predicted membrane protein (DUF2157) Flavi_capsid PF01003.19 EKX43203.1 - 0.02 14.6 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Flavivirus capsid protein C DLP_helical PF18709.1 EKX43203.1 - 0.032 13.5 6.5 0.05 12.8 6.5 1.2 1 0 0 1 1 1 0 Dynamin-like helical domain CCDC142 PF14923.6 EKX43203.1 - 0.039 12.7 0.6 0.052 12.3 0.6 1.1 1 0 0 1 1 1 0 Coiled-coil protein 142 Ribosomal_L37 PF08561.10 EKX43203.1 - 0.16 12.5 3.7 0.26 11.8 3.7 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 TMPIT PF07851.13 EKX43203.1 - 0.18 11.0 3.8 0.24 10.6 3.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein USP8_interact PF08941.10 EKX43203.1 - 0.27 11.0 4.7 0.4 10.5 4.7 1.2 1 0 0 1 1 1 0 USP8 interacting SlyX PF04102.12 EKX43203.1 - 0.34 11.6 4.7 0.78 10.4 4.7 1.7 1 0 0 1 1 1 0 SlyX Ly49 PF08391.10 EKX43203.1 - 1.8 8.9 6.7 3.1 8.2 0.0 2.2 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Kinesin PF00225.23 EKX43204.1 - 2.1e-125 418.1 0.1 3.7e-125 417.3 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX43204.1 - 6e-30 104.2 0.0 2.1e-29 102.4 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding PIF1 PF05970.14 EKX43204.1 - 0.034 13.3 0.0 0.082 12.1 0.0 1.6 1 0 0 1 1 1 0 PIF1-like helicase AAA_16 PF13191.6 EKX43204.1 - 0.085 13.2 3.1 0.94 9.8 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain Kinesin_assoc PF16183.5 EKX43204.1 - 0.24 11.5 17.7 0.19 11.8 14.1 2.6 2 1 0 2 2 2 0 Kinesin-associated THOC2_N PF16134.5 EKX43205.1 - 0.11 11.1 0.1 0.17 10.5 0.1 1.2 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus DUF1459 PF07312.11 EKX43206.1 - 0.36 11.1 5.9 0.4 10.9 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1459) NTF2 PF02136.20 EKX43207.1 - 3.3e-13 50.3 0.0 1.6e-12 48.0 0.0 1.8 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DEAD PF00270.29 EKX43208.1 - 5.1e-44 150.1 0.2 9.6e-44 149.2 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX43208.1 - 6e-33 113.5 0.3 2.9e-31 108.1 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX43208.1 - 1.1e-07 32.0 0.1 4.9e-07 29.9 0.0 2.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EKX43208.1 - 0.00053 20.3 2.1 0.0044 17.3 2.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EKX43208.1 - 0.0011 19.3 0.0 0.0024 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 EKX43208.1 - 0.0044 16.9 0.0 0.0083 16.0 0.0 1.4 1 0 0 1 1 1 1 Helicase UTP25 PF06862.12 EKX43208.1 - 0.017 13.9 0.8 0.55 8.9 0.3 2.4 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 LysM PF01476.20 EKX43209.1 - 0.00031 20.7 0.4 0.0071 16.4 0.1 2.7 2 0 0 2 2 2 1 LysM domain UAA PF08449.11 EKX43210.1 - 1.1e-43 149.6 24.8 1.2e-43 149.5 24.8 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EKX43210.1 - 0.086 13.0 26.6 1.2 9.3 14.9 2.8 2 1 0 2 2 2 0 EamA-like transporter family SLATT_1 PF18181.1 EKX43210.1 - 0.89 9.5 4.3 3.9 7.4 0.1 2.5 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Lectin_C PF00059.21 EKX43211.1 - 5.8e-10 39.9 0.0 6.4e-10 39.7 0.0 1.0 1 0 0 1 1 1 1 Lectin C-type domain PUB_1 PF18486.1 EKX43212.1 - 0.096 12.6 0.2 0.14 12.1 0.2 1.2 1 0 0 1 1 1 0 PNGase/UBA- or UBX-containing domain PKD_channel PF08016.12 EKX43213.1 - 3.4e-13 49.1 9.7 1.1e-05 24.4 6.3 3.0 1 1 2 3 3 3 3 Polycystin cation channel Ion_trans PF00520.31 EKX43213.1 - 0.048 12.9 6.6 0.12 11.6 6.9 1.4 1 1 0 1 1 1 0 Ion transport protein Ank_2 PF12796.7 EKX43214.1 - 9.1e-22 77.5 0.2 2.4e-10 40.9 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX43214.1 - 1.9e-17 63.4 0.9 1.5e-08 35.0 0.0 3.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX43214.1 - 1.7e-16 59.9 0.7 0.00046 20.5 0.4 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EKX43214.1 - 2.3e-12 45.9 0.7 0.00016 21.8 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EKX43214.1 - 3.6e-12 46.3 0.5 1.3e-05 25.4 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Myb_DNA-binding PF00249.31 EKX43216.1 - 1.9e-32 111.2 4.7 9.8e-16 57.7 1.4 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX43216.1 - 2.5e-28 98.1 2.4 1.3e-18 67.0 1.4 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EKX43216.1 - 2.5e-08 33.7 0.0 7.5e-05 22.5 0.0 2.1 1 1 1 2 2 2 2 Myb DNA-binding like Sigma70_r4_2 PF08281.12 EKX43216.1 - 0.00012 21.6 0.0 0.021 14.5 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 SANT_DAMP1_like PF16282.5 EKX43216.1 - 0.0014 18.8 0.8 0.17 12.1 0.1 2.2 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 EKX43216.1 - 0.0056 16.7 0.1 0.97 9.5 0.0 2.1 1 1 1 2 2 2 2 SLIDE Exo70 PF03081.15 EKX43216.1 - 0.015 14.3 0.4 0.053 12.6 0.4 1.8 1 1 0 1 1 1 0 Exo70 exocyst complex subunit Myb_DNA-bind_4 PF13837.6 EKX43216.1 - 0.026 14.9 1.0 0.12 12.7 0.1 2.3 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain HTH_23 PF13384.6 EKX43216.1 - 0.035 13.9 0.7 6.9 6.6 0.0 2.5 2 1 0 2 2 2 0 Homeodomain-like domain Myb_DNA-bind_2 PF08914.11 EKX43216.1 - 0.053 13.7 0.8 0.28 11.4 0.3 2.2 1 1 1 2 2 2 0 Rap1 Myb domain Myb_DNA-bind_5 PF13873.6 EKX43216.1 - 0.11 12.6 7.0 1.9 8.6 0.2 3.4 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain HIGH_NTase1_ass PF16581.5 EKX43216.1 - 0.12 12.3 0.0 7.5 6.5 0.1 2.0 2 0 0 2 2 2 0 Cytidyltransferase-related C-terminal region Spore_III_AB PF09548.10 EKX43216.1 - 0.21 11.7 0.1 0.25 11.4 0.1 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Sulfotransfer_1 PF00685.27 EKX43217.1 - 0.00021 20.9 0.1 0.00029 20.4 0.1 1.3 1 0 0 1 1 1 1 Sulfotransferase domain DUF155 PF02582.14 EKX43218.1 - 8.9e-37 126.9 0.1 6.9e-35 120.7 0.1 2.5 1 1 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Radial_spoke PF04712.12 EKX43219.1 - 1.5e-08 34.1 0.0 4.7e-06 25.8 0.0 2.4 2 1 0 2 2 2 2 Radial spokehead-like protein DUF4787 PF16029.5 EKX43220.1 - 3.4e-17 62.3 7.7 4.7e-17 61.8 7.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4787) Fer4_22 PF17179.4 EKX43220.1 - 0.0043 17.9 1.6 0.0077 17.1 1.6 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Ion_trans PF00520.31 EKX43221.1 - 1.6e-21 76.7 11.2 2e-21 76.3 11.2 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX43221.1 - 2.2e-12 46.8 1.1 2.2e-12 46.8 1.1 1.9 2 0 0 2 2 2 1 Ion channel Sid-5 PF17204.3 EKX43221.1 - 0.22 11.7 5.0 16 5.8 5.2 2.4 2 0 0 2 2 2 0 Sid-5 family IRK PF01007.20 EKX43221.1 - 0.78 9.6 3.5 0.68 9.7 1.5 1.9 2 1 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain SNARE PF05739.19 EKX43222.1 - 0.00012 22.0 0.3 0.00045 20.1 0.1 2.0 2 0 0 2 2 2 1 SNARE domain APC_N_CC PF16689.5 EKX43222.1 - 0.16 12.1 6.1 1.7 8.7 2.9 3.0 3 0 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain BRE1 PF08647.11 EKX43222.1 - 2.3 8.3 12.2 0.13 12.4 4.3 2.6 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase CENP-Q PF13094.6 EKX43222.1 - 3.2 7.9 9.9 7.4 6.7 2.7 2.4 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Phage_GPO PF05929.11 EKX43222.1 - 6.8 6.2 7.5 2.4 7.7 0.2 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Sugar_tr PF00083.24 EKX43223.1 - 7.2e-19 68.0 6.7 8.3e-19 67.8 6.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EKX43223.1 - 1.8e-14 53.5 14.9 8.3e-14 51.3 15.0 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EKX43223.1 - 0.0026 16.3 1.2 0.0034 15.9 1.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 EKX43223.1 - 0.0033 16.0 2.1 0.0034 16.0 1.1 1.5 1 1 0 1 1 1 1 MFS/sugar transport protein DUF1664 PF07889.12 EKX43224.1 - 0.1 12.7 10.0 0.37 10.8 1.2 3.4 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 EKX43224.1 - 0.15 12.4 0.5 48 4.3 0.0 3.2 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) LPP PF04728.13 EKX43224.1 - 0.16 12.4 4.0 32 5.0 0.2 4.2 4 0 0 4 4 4 0 Lipoprotein leucine-zipper Laminin_II PF06009.12 EKX43224.1 - 0.68 9.9 11.9 0.088 12.8 1.1 3.4 2 1 1 3 3 3 0 Laminin Domain II MbeB_N PF04837.12 EKX43224.1 - 0.98 9.8 12.6 3.9 7.9 2.1 3.8 2 1 1 3 3 3 0 MbeB-like, N-term conserved region Lebercilin PF15619.6 EKX43224.1 - 2 8.1 35.6 0.81 9.3 9.6 3.0 2 2 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease TACC_C PF05010.14 EKX43224.1 - 3.1 7.5 26.1 1.4 8.7 7.5 2.2 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Prominin PF05478.11 EKX43224.1 - 5.1 4.9 8.7 0.51 8.2 4.0 1.5 2 0 0 2 2 2 0 Prominin ANF_receptor PF01094.28 EKX43226.1 - 9.9e-36 123.6 0.0 1.6e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 EKX43226.1 - 2.4e-14 53.7 0.4 3.9e-11 43.2 0.1 2.1 2 0 0 2 2 2 2 Periplasmic binding protein PDZ_2 PF13180.6 EKX43228.1 - 0.013 15.8 0.7 0.026 14.9 0.7 1.5 1 1 0 1 1 1 0 PDZ domain NeA_P2 PF12312.8 EKX43228.1 - 0.013 14.9 0.3 0.021 14.3 0.3 1.4 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein ANF_receptor PF01094.28 EKX43229.1 - 4.2e-35 121.5 0.0 6.8e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 EKX43229.1 - 4.4e-14 52.9 0.5 6.5e-11 42.5 0.1 2.1 2 0 0 2 2 2 2 Periplasmic binding protein CALCOCO1 PF07888.11 EKX43229.1 - 0.06 12.2 0.7 0.11 11.3 0.7 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like RWP-RK PF02042.15 EKX43230.1 - 7.5e-17 61.1 0.0 1.3e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain BRCT_3 PF18428.1 EKX43231.1 - 2.7e-06 27.4 0.7 6.1 7.0 0.0 5.9 6 0 0 6 6 6 2 BRCA1 C Terminus (BRCT) domain UPF0158 PF03682.13 EKX43231.1 - 0.0012 18.9 0.2 2.9 7.8 0.1 3.9 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0158) Med7 PF05983.11 EKX43231.1 - 0.013 15.6 0.5 1.7 8.7 0.0 3.1 2 0 0 2 2 2 0 MED7 protein Histone PF00125.24 EKX43231.1 - 0.015 15.6 0.9 0.9 9.9 0.1 4.1 4 0 0 4 4 4 0 Core histone H2A/H2B/H3/H4 GAT PF03127.14 EKX43231.1 - 0.016 15.5 1.2 26 5.2 0.0 4.5 4 0 0 4 4 4 0 GAT domain DUF1299 PF06975.11 EKX43231.1 - 0.068 13.3 0.1 0.16 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1299) Exonuc_VII_L PF02601.15 EKX43231.1 - 0.098 12.2 1.1 14 5.1 0.1 3.3 4 0 0 4 4 4 0 Exonuclease VII, large subunit GRP PF07172.11 EKX43231.1 - 0.37 11.5 15.1 0.87 10.3 15.1 1.6 1 0 0 1 1 1 0 Glycine rich protein family DUF4519 PF15012.6 EKX43232.1 - 0.2 11.9 4.0 9.3 6.5 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Afaf PF15339.6 EKX43232.1 - 6.9 6.3 7.7 1.3 8.8 0.1 2.2 1 1 1 2 2 2 0 Acrosome formation-associated factor Sec62 PF03839.16 EKX43232.1 - 8.6 5.8 7.2 11 5.5 7.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 PHD PF00628.29 EKX43233.1 - 5.3e-07 29.4 8.0 1e-06 28.5 8.0 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EKX43233.1 - 2.9 7.5 6.1 0.27 10.8 1.3 1.9 2 0 0 2 2 2 0 PHD-finger RWP-RK PF02042.15 EKX43234.1 - 2.7e-15 56.0 0.0 7e-15 54.7 0.0 1.6 2 0 0 2 2 2 1 RWP-RK domain Kelch_3 PF13415.6 EKX43235.1 - 9.1e-22 76.8 0.5 1.4e-06 28.5 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EKX43235.1 - 2.4e-20 72.1 1.3 2.2e-06 27.5 0.0 5.6 5 1 1 6 6 6 4 Kelch motif Kelch_4 PF13418.6 EKX43235.1 - 4.5e-19 68.2 0.3 0.00013 21.9 0.0 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.25 EKX43235.1 - 3.7e-17 61.6 0.0 8e-07 28.5 0.0 5.2 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 EKX43235.1 - 2.5e-13 49.8 0.8 0.00017 21.8 0.0 5.4 3 1 2 5 5 5 3 Kelch motif Kelch_2 PF07646.15 EKX43235.1 - 2.3e-11 43.2 3.4 0.0016 18.4 0.0 5.3 4 1 1 5 5 5 4 Kelch motif TPT PF03151.16 EKX43236.1 - 2.5e-28 99.3 17.8 6.3e-19 68.4 8.3 1.9 2 0 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 EKX43236.1 - 0.00011 22.4 35.0 0.00049 20.3 9.1 3.0 3 0 0 3 3 3 2 EamA-like transporter family DUF2070 PF09843.9 EKX43236.1 - 0.0033 15.8 2.3 0.0033 15.8 2.3 2.1 2 0 0 2 2 2 1 Predicted membrane protein (DUF2070) UAA PF08449.11 EKX43236.1 - 0.0035 16.6 6.2 0.0035 16.6 6.2 2.3 2 0 0 2 2 2 2 UAA transporter family PUNUT PF16913.5 EKX43236.1 - 0.041 13.1 22.5 0.025 13.8 6.8 3.1 2 1 1 3 3 3 0 Purine nucleobase transmembrane transport COX4_pro PF03626.14 EKX43236.1 - 4.2 7.8 11.2 0.16 12.4 2.2 3.2 2 2 0 2 2 2 0 Prokaryotic Cytochrome C oxidase subunit IV Chloroa_b-bind PF00504.21 EKX43237.1 - 2.1e-19 70.6 0.0 2.8e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Histone PF00125.24 EKX43239.1 - 1.1e-53 181.0 3.2 1.3e-53 180.9 3.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EKX43239.1 - 3.9e-05 23.7 0.6 5.8e-05 23.2 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EKX43239.1 - 7.3e-05 23.1 0.1 0.00011 22.5 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 EKX43239.1 - 0.00022 21.8 1.5 0.00027 21.5 1.5 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain TFIID-31kDa PF02291.15 EKX43239.1 - 0.022 14.8 0.3 0.039 14.0 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 EKX43239.1 - 0.027 14.7 1.0 0.033 14.5 0.1 1.6 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PRKG1_interact PF15898.5 EKX43242.1 - 0.0024 18.7 14.0 0.0024 18.7 14.0 4.6 2 2 2 4 4 4 2 cGMP-dependent protein kinase interacting domain MazG PF03819.17 EKX43242.1 - 0.0068 16.6 1.0 0.024 14.8 1.0 1.9 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain ADIP PF11559.8 EKX43242.1 - 0.019 15.0 12.6 0.019 15.0 12.6 4.9 1 1 5 6 6 6 0 Afadin- and alpha -actinin-Binding Filament PF00038.21 EKX43242.1 - 0.36 10.4 55.5 0.0093 15.6 25.7 3.6 1 1 2 3 3 3 0 Intermediate filament protein Bacillus_HBL PF05791.11 EKX43242.1 - 2.1 8.1 28.1 0.21 11.4 7.0 4.2 3 1 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) DUF1664 PF07889.12 EKX43242.1 - 8.2 6.5 31.7 0.093 12.8 6.6 4.4 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) UBA_4 PF14555.6 EKX43243.1 - 2.3e-11 43.3 0.0 4.2e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain SEP PF08059.13 EKX43243.1 - 1.7e-09 38.1 1.0 2.4e-09 37.6 0.1 1.8 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 EKX43243.1 - 0.0092 16.2 0.0 0.022 14.9 0.0 1.6 1 0 0 1 1 1 1 UBX domain Kinesin PF00225.23 EKX43246.1 - 1.8e-67 227.6 1.0 2.5e-67 227.2 1.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX43246.1 - 6.3e-16 58.6 0.1 6.2e-14 52.2 0.2 2.6 1 1 0 1 1 1 1 Microtubule binding TRIF-NTD PF17798.1 EKX43246.1 - 0.073 13.2 0.2 0.2 11.7 0.2 1.7 1 1 0 1 1 1 0 TRIF N-terminal domain Profilin PF00235.19 EKX43248.1 - 2.9e-18 66.4 0.0 3.4e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Profilin Ion_trans PF00520.31 EKX43249.1 - 1.7e-60 204.3 44.8 7.7e-32 110.4 18.6 2.2 2 0 0 2 2 2 2 Ion transport protein EF-hand_1 PF00036.32 EKX43249.1 - 8.1e-14 50.1 3.1 0.0036 16.8 0.2 4.6 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EKX43249.1 - 5.8e-11 41.4 3.3 0.087 12.8 0.0 5.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 EKX43249.1 - 4.9e-10 39.7 0.2 0.11 12.9 0.0 4.9 3 0 0 3 3 3 3 EF-hand domain pair PKD_channel PF08016.12 EKX43249.1 - 1.3e-09 37.3 36.6 2.9e-05 23.0 10.2 3.7 2 2 2 4 4 4 3 Polycystin cation channel EF-hand_5 PF13202.6 EKX43249.1 - 3.8e-08 32.5 4.7 0.0054 16.2 0.1 4.0 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EKX43249.1 - 6.7e-06 25.9 0.9 2.1 8.2 0.0 4.3 3 0 0 3 3 3 2 EF-hand domain pair PH PF00169.29 EKX43249.1 - 0.00066 20.2 0.0 0.024 15.1 0.0 2.7 2 0 0 2 2 2 1 PH domain EF-hand_4 PF12763.7 EKX43249.1 - 0.0012 18.7 0.6 12 6.0 0.0 4.1 3 1 1 4 4 4 1 Cytoskeletal-regulatory complex EF hand gpD PF02925.16 EKX43249.1 - 0.021 14.8 0.0 0.69 9.9 0.0 2.8 3 0 0 3 3 3 0 Bacteriophage scaffolding protein D Myosin_N PF02736.19 EKX43249.1 - 0.051 13.4 1.4 0.092 12.6 0.4 2.0 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain KCNQ_channel PF03520.14 EKX43249.1 - 0.25 11.2 3.5 0.7 9.7 2.1 2.3 2 0 0 2 2 2 0 KCNQ voltage-gated potassium channel Phage_GPO PF05929.11 EKX43249.1 - 0.6 9.7 7.0 1.7 8.2 7.0 1.7 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase TMF_TATA_bd PF12325.8 EKX43249.1 - 0.95 9.7 9.7 2.6 8.3 0.4 4.4 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding Glyco_transf_41 PF13844.6 EKX43250.1 - 1.3e-15 56.8 0.0 1.7e-07 30.1 0.0 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_14 PF13428.6 EKX43250.1 - 0.0004 21.0 3.1 0.004 17.9 0.4 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX43250.1 - 0.00044 20.1 0.9 0.22 11.7 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX43250.1 - 0.0008 19.4 0.1 0.37 11.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX43250.1 - 0.0015 18.2 0.1 0.11 12.3 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX43250.1 - 0.01 15.7 3.9 1.5 8.8 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX43250.1 - 0.025 14.9 2.7 0.071 13.4 0.2 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EKX43250.1 - 0.03 14.4 3.2 1.6 9.0 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Complex1_LYR_1 PF13232.6 EKX43251.1 - 0.021 15.4 0.2 0.048 14.3 0.0 1.7 2 0 0 2 2 2 0 Complex1_LYR-like Pex2_Pex12 PF04757.14 EKX43251.1 - 0.096 12.3 0.1 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region EF-hand_7 PF13499.6 EKX43252.1 - 5.7e-16 58.7 9.4 1.4e-10 41.5 0.9 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX43252.1 - 6.4e-15 53.5 15.8 0.00028 20.2 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EKX43252.1 - 6.8e-13 47.4 8.3 0.00034 20.3 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EKX43252.1 - 7.5e-13 48.1 11.3 2e-07 30.7 0.7 4.4 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EKX43252.1 - 8.9e-05 21.8 0.5 8.9e-05 21.8 0.5 4.1 5 0 0 5 5 5 1 EF hand DUF3349 PF11829.8 EKX43252.1 - 0.028 15.2 0.1 1.3 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) EF-hand_4 PF12763.7 EKX43252.1 - 0.26 11.2 6.6 14 5.7 0.0 3.0 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand PEX11 PF05648.14 EKX43253.1 - 1.1e-20 74.0 0.1 7.8e-20 71.3 0.0 1.9 1 1 1 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) RT_RNaseH PF17917.1 EKX43254.1 - 0.029 14.6 0.5 1.5 9.1 0.1 2.8 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase TLE_N PF03920.15 EKX43254.1 - 7.4 6.7 21.0 0.56 10.3 3.4 4.2 3 0 0 3 3 3 0 Groucho/TLE N-terminal Q-rich domain PDZ_6 PF17820.1 EKX43256.1 - 9.4e-09 35.0 1.7 1.3e-08 34.6 0.1 2.1 3 0 0 3 3 3 1 PDZ domain PDZ PF00595.24 EKX43256.1 - 2.9e-08 33.9 0.4 7.3e-08 32.7 0.4 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX43256.1 - 1.3e-06 28.6 0.1 3.6e-06 27.2 0.1 1.8 1 0 0 1 1 1 1 PDZ domain Arm PF00514.23 EKX43256.1 - 6e-06 26.1 3.7 0.17 11.9 0.0 4.2 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EKX43256.1 - 3.9e-05 24.0 0.1 0.00067 20.0 0.0 2.6 2 0 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 EKX43256.1 - 6e-05 23.5 1.4 0.14 12.7 0.1 3.8 2 1 1 3 3 3 2 HEAT-like repeat HEAT PF02985.22 EKX43256.1 - 0.017 15.3 1.2 4.7 7.8 0.0 3.4 4 0 0 4 4 4 0 HEAT repeat Tricorn_PDZ PF14685.6 EKX43256.1 - 0.03 14.3 0.0 0.07 13.1 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain Nbl1_Borealin_N PF10444.9 EKX43256.1 - 1.2 8.8 6.8 1.6 8.4 1.0 3.4 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal Vps39_2 PF10367.9 EKX43256.1 - 9.1 6.8 6.3 1.2 9.6 0.6 2.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 HD_4 PF13328.6 EKX43257.1 - 1.1e-52 178.0 1.5 1.3e-52 177.7 0.2 1.8 2 0 0 2 2 2 1 HD domain RelA_SpoT PF04607.17 EKX43257.1 - 5.8e-39 133.0 1.0 5.8e-38 129.8 0.0 2.5 2 1 1 3 3 3 1 Region found in RelA / SpoT proteins HD PF01966.22 EKX43257.1 - 4e-10 40.0 0.1 1.6e-09 38.1 0.1 2.0 2 1 1 3 3 3 1 HD domain DNA_pol3_gamma3 PF12169.8 EKX43257.1 - 0.012 15.5 0.1 0.037 13.9 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III HAD_SAK_1 PF10307.9 EKX43257.1 - 0.04 13.7 0.1 0.04 13.7 0.1 2.3 3 0 0 3 3 3 0 HAD domain family 1 in Swiss Army Knife RNA repair proteins ACT_4 PF13291.6 EKX43258.1 - 2e-13 50.7 0.0 2.7e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 EKX43258.1 - 6.3e-06 25.9 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 ACT domain Ion_trans PF00520.31 EKX43259.1 - 7e-15 54.9 8.5 9.3e-15 54.5 8.5 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX43259.1 - 3.5e-09 36.5 0.4 3.5e-09 36.5 0.4 2.7 3 0 0 3 3 3 1 Ion channel Phycoerythr_ab PF02972.14 EKX43260.1 - 1.6e-19 69.5 0.0 3.3e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 Phycoerythrin, alpha/beta chain TAT_signal PF10518.9 EKX43260.1 - 0.085 12.7 1.3 0.085 12.7 1.3 2.4 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence DUF3577 PF12101.8 EKX43260.1 - 0.13 12.0 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3577) Fcf1 PF04900.12 EKX43263.1 - 3.6e-39 133.1 2.5 3.6e-39 133.1 2.5 1.4 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 EKX43263.1 - 6.9e-13 48.9 0.1 1.7e-12 47.7 0.0 1.6 2 0 0 2 2 2 1 PIN like domain DUF116 PF01976.17 EKX43263.1 - 0.0048 16.4 1.2 0.0072 15.9 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF116 E1_dh PF00676.20 EKX43264.1 - 4.4e-107 357.5 0.0 5.6e-107 357.1 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EKX43264.1 - 0.011 14.9 0.2 0.022 14.0 0.2 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 EKX43264.1 - 0.019 14.8 0.1 0.043 13.6 0.1 1.7 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.21 EKX43264.1 - 0.033 13.2 0.0 0.054 12.4 0.0 1.3 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain MA3 PF02847.17 EKX43265.1 - 6.1e-80 264.6 0.0 1.6e-22 79.6 0.0 4.1 4 0 0 4 4 4 4 MA3 domain TBK1_CCD1 PF18394.1 EKX43265.1 - 0.0032 17.1 1.1 1.8 8.1 0.1 2.4 2 0 0 2 2 2 2 TANK-binding kinase 1 coiled-coil domain 1 DHDPS PF00701.22 EKX43265.1 - 0.0089 14.8 0.1 3.8 6.1 0.0 2.3 2 0 0 2 2 2 2 Dihydrodipicolinate synthetase family AAA_17 PF13207.6 EKX43265.1 - 0.009 16.4 3.1 0.61 10.5 0.1 3.0 4 0 0 4 4 4 1 AAA domain YtxC PF08812.11 EKX43265.1 - 0.016 14.8 0.0 7.5 6.1 0.0 2.4 2 0 0 2 2 2 0 YtxC-like family PPR PF01535.20 EKX43265.1 - 0.028 14.6 0.2 47 4.6 0.0 4.1 4 0 0 4 4 4 0 PPR repeat HATPase_c_4 PF13749.6 EKX43265.1 - 0.035 14.2 0.1 17 5.6 0.0 3.6 4 0 0 4 4 4 0 Putative ATP-dependent DNA helicase recG C-terminal Ku_PK_bind PF08785.11 EKX43265.1 - 0.065 13.4 0.0 36 4.5 0.0 3.2 3 0 0 3 3 3 0 Ku C terminal domain like TPR_5 PF12688.7 EKX43265.1 - 0.12 12.6 5.0 14 5.9 0.1 3.9 4 1 1 5 5 5 0 Tetratrico peptide repeat DUF4342 PF14242.6 EKX43265.1 - 0.25 11.4 1.9 1.1e+02 2.9 0.0 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4342) PhoD PF09423.10 EKX43266.1 - 4e-17 62.3 1.6 1.6e-15 57.0 1.6 3.0 1 1 0 1 1 1 1 PhoD-like phosphatase adh_short PF00106.25 EKX43268.1 - 8.7e-39 133.0 0.8 1e-36 126.3 0.8 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EKX43268.1 - 1.2e-26 93.8 1.5 3.3e-21 75.9 1.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX43268.1 - 1.1e-12 48.3 1.0 1.4e-11 44.6 1.0 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EKX43268.1 - 0.00043 19.8 0.3 0.16 11.4 0.3 2.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EKX43268.1 - 0.0042 17.0 1.7 0.02 14.8 1.7 2.1 1 1 0 1 1 1 1 NAD(P)H-binding HEM4 PF02602.15 EKX43268.1 - 0.019 14.3 0.1 0.041 13.2 0.1 1.5 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD 2-Hacid_dh_C PF02826.19 EKX43268.1 - 0.082 12.3 0.1 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RWP-RK PF02042.15 EKX43269.1 - 1.1e-10 41.3 0.1 2e-10 40.5 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain LRR_4 PF12799.7 EKX43270.1 - 6.4e-20 70.9 36.1 3.1e-08 33.8 2.7 4.3 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX43270.1 - 1.4e-13 50.4 31.9 8e-07 28.7 8.0 3.6 1 1 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 EKX43270.1 - 2.2e-10 40.3 6.8 4.9e-07 29.4 3.2 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 EKX43270.1 - 0.0003 20.6 16.4 2.2 8.6 0.0 5.3 5 0 0 5 5 5 4 Leucine Rich repeat LRR_1 PF00560.33 EKX43270.1 - 0.0065 16.8 18.0 6.8 7.7 0.0 5.9 7 0 0 7 7 7 3 Leucine Rich Repeat NosD PF05048.13 EKX43270.1 - 0.18 11.0 0.7 0.25 10.6 0.7 1.1 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Serendipity_A PF05482.12 EKX43271.1 - 0.015 14.0 0.1 0.019 13.6 0.1 1.0 1 0 0 1 1 1 0 Serendipity locus alpha protein (SRY-A) Aminotran_MocR PF12897.7 EKX43271.1 - 0.026 13.3 0.0 0.034 12.9 0.0 1.1 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase Amino_oxidase PF01593.24 EKX43273.1 - 4.2e-74 250.5 11.6 5.9e-49 167.6 0.3 3.5 4 0 0 4 4 4 3 Flavin containing amine oxidoreductase SWIRM PF04433.17 EKX43273.1 - 2.2e-10 40.7 0.0 6.3e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.6 EKX43273.1 - 3.4e-10 40.0 1.2 1.3e-09 38.1 1.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EKX43273.1 - 5.4e-10 39.2 0.1 1.2e-09 38.0 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase TUDOR PF00567.24 EKX43273.1 - 1.5e-09 37.9 0.2 0.093 12.8 0.0 3.5 3 0 0 3 3 3 3 Tudor domain FAD_binding_2 PF00890.24 EKX43273.1 - 8.5e-09 35.0 0.3 1.5e-08 34.1 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Agenet PF05641.12 EKX43273.1 - 9.8e-09 35.6 0.1 0.21 12.1 0.0 3.8 3 0 0 3 3 3 3 Agenet domain DAO PF01266.24 EKX43273.1 - 1.5e-07 31.4 1.5 1.5e-07 31.4 1.5 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EKX43273.1 - 3.5e-06 26.5 0.1 7.2e-06 25.4 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EKX43273.1 - 7.9e-06 25.3 0.6 7.9e-06 25.3 0.6 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 EKX43273.1 - 9.5e-06 25.1 0.5 4e-05 23.0 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EKX43273.1 - 1.2e-05 24.2 1.0 2.2e-05 23.4 1.0 1.4 1 0 0 1 1 1 1 HI0933-like protein DUF4537 PF15057.6 EKX43273.1 - 2.3e-05 24.4 0.1 0.64 10.1 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4537) GIDA PF01134.22 EKX43273.1 - 0.0001 21.5 1.6 0.00018 20.7 1.6 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EKX43273.1 - 0.00058 19.0 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 EKX43273.1 - 0.0019 18.7 2.7 0.0028 18.2 0.8 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Tudor_FRX1 PF18336.1 EKX43273.1 - 0.002 18.0 0.5 9.6 6.2 0.0 4.0 4 0 0 4 4 4 0 Fragile X mental retardation Tudor domain PCB_OB PF17092.5 EKX43273.1 - 0.0022 18.7 0.6 0.52 11.1 0.1 3.6 3 0 0 3 3 3 1 Penicillin-binding protein OB-like domain Pyr_redox_3 PF13738.6 EKX43273.1 - 0.0033 16.7 0.0 0.006 15.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EKX43273.1 - 0.0061 15.9 3.2 0.011 15.0 3.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain RNA_pol_Rpc4 PF05132.14 EKX43273.1 - 0.014 15.8 1.0 0.014 15.8 1.0 3.3 4 0 0 4 4 3 0 RNA polymerase III RPC4 Trp_halogenase PF04820.14 EKX43273.1 - 0.042 12.7 0.8 0.064 12.1 0.8 1.2 1 0 0 1 1 1 0 Tryptophan halogenase MCRA PF06100.11 EKX43273.1 - 0.11 11.2 0.1 0.17 10.6 0.1 1.2 1 0 0 1 1 1 0 MCRA family Peptidase_M50 PF02163.22 EKX43275.1 - 1.2 8.4 6.3 1.2 8.4 6.3 1.1 1 0 0 1 1 1 0 Peptidase family M50 Anoctamin PF04547.12 EKX43275.1 - 1.3 7.8 13.1 1.6 7.5 13.1 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel LRR_6 PF13516.6 EKX43276.1 - 0.031 14.3 5.7 0.061 13.4 0.1 3.4 4 0 0 4 4 4 0 Leucine Rich repeat LRR_4 PF12799.7 EKX43276.1 - 0.055 13.9 0.2 6.4 7.4 0.0 3.1 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) DUF3990 PF13151.6 EKX43278.1 - 0.051 13.2 0.0 0.067 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3990) MRNIP PF15749.5 EKX43280.1 - 6.5e-15 55.8 49.5 3.4e-12 47.0 39.0 3.7 1 1 1 2 2 2 1 MRN-interacting protein Zn-ribbon_8 PF09723.10 EKX43280.1 - 0.0033 17.5 1.2 0.0072 16.4 1.2 1.6 1 0 0 1 1 1 1 Zinc ribbon domain FlhC PF05280.11 EKX43280.1 - 0.17 11.6 1.3 0.31 10.8 1.3 1.3 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) zinc_ribbon_10 PF10058.9 EKX43280.1 - 0.21 11.4 1.9 0.51 10.1 1.9 1.7 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-MIZ PF02891.20 EKX43280.1 - 0.26 11.1 2.0 0.6 9.9 2.0 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Elf1 PF05129.13 EKX43280.1 - 0.46 10.6 6.9 0.082 13.0 2.0 2.2 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like RRM_1 PF00076.22 EKX43281.1 - 1.3e-43 146.7 0.4 5.5e-18 64.5 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EKX43281.1 - 5.9e-06 25.9 0.0 0.5 10.0 0.0 3.3 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EKX43281.1 - 0.0012 18.7 0.3 16 5.4 0.0 3.9 4 0 0 4 4 4 2 Occluded RNA-recognition motif DUF1866 PF08952.11 EKX43281.1 - 0.12 12.3 0.0 0.39 10.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) Na_H_Exchanger PF00999.21 EKX43282.1 - 1.2e-17 63.8 40.8 9.4e-17 60.9 23.9 3.0 2 1 0 2 2 2 2 Sodium/hydrogen exchanger family TrkA_N PF02254.18 EKX43282.1 - 0.029 14.6 0.0 0.92 9.8 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Vfa1 PF08432.10 EKX43282.1 - 1.2 9.5 6.5 1.8 8.9 6.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Phycoerythr_ab PF02972.14 EKX43283.1 - 1.7e-46 155.8 0.1 2.9e-23 81.4 0.0 2.2 2 0 0 2 2 2 2 Phycoerythrin, alpha/beta chain SOUL PF04832.12 EKX43284.1 - 1.9e-13 51.0 0.8 3e-13 50.3 0.8 1.2 1 0 0 1 1 1 1 SOUL heme-binding protein Myc_N PF01056.18 EKX43284.1 - 0.0075 16.2 0.1 0.0097 15.8 0.1 1.1 1 0 0 1 1 1 1 Myc amino-terminal region CAF1-p150_C2 PF15539.6 EKX43284.1 - 0.051 13.0 0.1 0.075 12.5 0.1 1.2 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term CAF-1_p150 PF11600.8 EKX43285.1 - 0.13 12.0 30.3 0.21 11.3 30.3 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal BCIP PF13862.6 EKX43285.1 - 0.32 10.8 3.7 0.58 9.9 3.7 1.4 1 0 0 1 1 1 0 p21-C-terminal region-binding protein DUF1682 PF07946.14 EKX43285.1 - 0.34 10.1 19.7 0.014 14.7 13.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) NARP1 PF12569.8 EKX43285.1 - 1.2 7.9 13.6 1.7 7.5 13.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.12 EKX43285.1 - 1.7 8.4 14.8 2.8 7.7 14.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 VIT1 PF01988.19 EKX43285.1 - 5.1 6.9 6.1 8.4 6.2 6.1 1.4 1 0 0 1 1 1 0 VIT family DUF5423 PF17461.2 EKX43285.1 - 6.4 5.5 7.6 1.4 7.7 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5423) PP2C PF00481.21 EKX43286.1 - 4.4e-42 144.5 0.0 6.2e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EKX43286.1 - 0.012 15.6 0.0 2.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) DUF1664 PF07889.12 EKX43287.1 - 0.005 16.9 0.7 0.005 16.9 0.7 6.3 2 2 5 7 7 7 3 Protein of unknown function (DUF1664) PKcGMP_CC PF16808.5 EKX43287.1 - 0.026 14.4 0.8 0.026 14.4 0.8 7.3 8 0 0 8 8 8 0 Coiled-coil N-terminus of cGMP-dependent protein kinase WD40_alt PF14077.6 EKX43287.1 - 0.47 10.4 10.5 0.54 10.2 1.6 4.4 4 1 1 5 5 5 0 Alternative WD40 repeat motif Pkinase PF00069.25 EKX43288.1 - 7.1e-17 61.6 0.0 1.5e-16 60.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX43288.1 - 0.056 12.7 0.8 0.098 11.9 0.0 1.8 3 0 0 3 3 3 0 Protein tyrosine kinase Aminotran_1_2 PF00155.21 EKX43290.1 - 6.5e-15 55.2 0.0 2e-06 27.2 0.0 3.7 1 1 2 3 3 3 3 Aminotransferase class I and II DUF630 PF04783.12 EKX43290.1 - 0.054 13.7 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF630) HMG_box PF00505.19 EKX43291.1 - 3.6e-41 139.4 16.5 3.5e-21 75.4 4.0 2.1 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EKX43291.1 - 3.4e-29 101.2 13.1 1.8e-14 54.0 4.0 2.1 2 0 0 2 2 2 2 HMG-box domain CHDNT PF08073.12 EKX43291.1 - 4.9e-06 26.4 0.0 0.052 13.5 0.0 2.6 2 0 0 2 2 2 2 CHDNT (NUC034) domain DUF3106 PF11304.8 EKX43291.1 - 0.012 16.0 2.5 0.28 11.7 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) Spore_III_AB PF09548.10 EKX43291.1 - 0.14 12.3 3.5 0.17 12.0 0.3 2.1 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) HMG_box_5 PF14887.6 EKX43291.1 - 3.5 7.7 10.8 0.1 12.6 3.7 2.0 2 0 0 2 2 2 0 HMG (high mobility group) box 5 CPBP PF02517.16 EKX43293.1 - 1.4e-10 41.4 1.0 2.3e-10 40.7 1.0 1.5 1 0 0 1 1 1 1 CPBP intramembrane metalloprotease EF-hand_5 PF13202.6 EKX43293.1 - 0.00028 20.3 0.0 0.021 14.3 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EKX43293.1 - 0.00054 19.7 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EKX43293.1 - 0.0021 17.9 0.0 1.5 8.8 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX43293.1 - 0.0055 16.2 0.0 1.7 8.4 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX43293.1 - 0.006 17.0 0.0 3 8.4 0.0 2.0 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_10 PF14788.6 EKX43293.1 - 0.0078 16.1 0.1 5.6 6.9 0.1 2.4 2 0 0 2 2 2 2 EF hand Pkinase PF00069.25 EKX43295.1 - 2.3e-16 60.0 0.0 2.9e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX43295.1 - 1.1e-12 47.9 0.0 1.5e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX43295.1 - 0.014 14.7 0.2 0.086 12.1 0.2 2.0 1 1 0 1 1 1 0 Kinase-like PCRF PF03462.18 EKX43297.1 - 2.5e-51 174.3 0.3 2.9e-51 174.1 0.3 1.0 1 0 0 1 1 1 1 PCRF domain Cyto_heme_lyase PF01265.17 EKX43298.1 - 3.1e-56 191.1 4.7 2.7e-55 188.0 4.7 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Ank_4 PF13637.6 EKX43299.1 - 9e-21 74.0 0.0 2.6e-07 31.1 0.1 3.7 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX43299.1 - 3.6e-17 62.7 2.6 6e-12 46.0 1.9 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EKX43299.1 - 2.6e-16 59.3 0.5 2.4e-05 24.6 0.1 4.9 4 1 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EKX43299.1 - 2.9e-15 56.1 3.3 2.4e-08 34.1 0.2 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX43299.1 - 1.3e-12 46.7 3.3 0.00012 22.2 0.1 4.4 4 0 0 4 4 4 3 Ankyrin repeat RWP-RK PF02042.15 EKX43300.1 - 1.2e-17 63.6 0.4 2.1e-17 62.8 0.4 1.4 1 0 0 1 1 1 1 RWP-RK domain TPR_1 PF00515.28 EKX43301.1 - 8.8e-46 151.9 22.2 5.6e-06 25.9 0.1 12.5 13 0 0 13 13 12 9 Tetratricopeptide repeat Glyco_transf_41 PF13844.6 EKX43301.1 - 8.3e-44 149.8 1.9 4.7e-22 78.1 0.0 3.3 1 1 2 3 3 3 3 Glycosyl transferase family 41 TPR_2 PF07719.17 EKX43301.1 - 1.2e-35 118.7 26.2 4.1e-05 23.4 0.1 13.5 12 1 1 13 13 13 9 Tetratricopeptide repeat TPR_8 PF13181.6 EKX43301.1 - 2.7e-29 98.9 13.0 5.9e-06 26.1 0.0 11.3 10 1 1 11 11 11 6 Tetratricopeptide repeat TPR_12 PF13424.6 EKX43301.1 - 1.1e-25 89.6 18.5 7.2e-06 26.2 0.0 8.2 4 2 4 8 8 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 EKX43301.1 - 5e-22 78.3 11.0 0.00081 20.0 0.0 7.6 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 EKX43301.1 - 1.1e-20 72.4 14.5 0.00038 20.6 0.4 9.8 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 EKX43301.1 - 1.1e-19 69.8 27.7 0.00036 20.1 0.1 9.5 7 3 2 9 9 9 5 TPR repeat TPR_7 PF13176.6 EKX43301.1 - 3e-19 67.6 10.2 0.047 13.7 0.0 10.8 11 1 1 12 12 11 5 Tetratricopeptide repeat TPR_14 PF13428.6 EKX43301.1 - 8.9e-17 60.4 16.2 0.016 16.0 0.0 10.5 5 5 5 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 EKX43301.1 - 1.4e-15 57.5 14.9 0.00071 20.0 0.1 6.7 5 3 2 7 7 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 EKX43301.1 - 8.8e-12 44.9 8.2 3.4 8.5 0.0 9.5 10 1 0 10 10 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX43301.1 - 2.9e-11 42.9 23.3 0.049 13.5 0.0 9.9 10 1 1 11 11 10 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX43301.1 - 3.8e-07 30.2 6.8 0.081 13.2 0.2 4.9 5 1 0 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EKX43301.1 - 1.2e-05 25.4 3.3 1.8 8.7 0.3 5.4 5 1 0 5 5 5 2 Tetratricopeptide repeat NARP1 PF12569.8 EKX43301.1 - 0.00048 19.2 5.9 0.39 9.6 2.3 3.4 2 1 2 4 4 4 2 NMDA receptor-regulated protein 1 DUF4919 PF16266.5 EKX43301.1 - 0.0005 20.1 1.2 0.0013 18.7 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4919) Wzy_C_2 PF11846.8 EKX43301.1 - 0.00063 19.7 5.0 0.13 12.1 1.6 3.3 2 1 1 3 3 3 1 Virulence factor membrane-bound polymerase, C-terminal SNAP PF14938.6 EKX43301.1 - 0.004 16.6 11.5 0.27 10.6 7.3 2.9 2 1 0 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_15 PF13429.6 EKX43301.1 - 0.0055 15.9 10.2 0.022 14.0 2.6 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 EKX43301.1 - 0.025 15.0 4.9 5.6 7.4 0.0 3.7 3 1 0 3 3 3 0 Bacterial transcriptional activator domain DUF3416 PF11896.8 EKX43301.1 - 0.054 13.8 2.4 0.12 12.6 2.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3416) FbpA PF05833.11 EKX43301.1 - 0.06 12.1 1.7 0.27 9.9 0.2 2.1 2 0 0 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) SPO22 PF08631.10 EKX43301.1 - 0.17 11.3 1.7 25 4.3 0.0 3.8 4 0 0 4 4 4 0 Meiosis protein SPO22/ZIP4 like TPR_3 PF07720.12 EKX43301.1 - 1.4 9.0 7.2 0.47 10.5 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 EKX43301.1 - 2 8.8 14.1 61 4.0 2.9 5.8 5 1 1 6 6 5 0 Tetratricopeptide repeat Ion_trans PF00520.31 EKX43302.1 - 7.5e-29 100.7 24.1 1.1e-28 100.2 24.1 1.2 1 0 0 1 1 1 1 Ion transport protein EF-hand_6 PF13405.6 EKX43302.1 - 0.02 14.8 0.1 0.41 10.7 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 EKX43302.1 - 0.027 14.0 0.1 2.3 8.0 0.0 3.5 3 0 0 3 3 3 0 EF hand PKD_channel PF08016.12 EKX43302.1 - 0.073 11.7 19.6 0.037 12.7 13.8 2.1 1 1 1 2 2 2 0 Polycystin cation channel LRR_8 PF13855.6 EKX43303.1 - 3.9e-78 257.1 49.7 1.4e-15 56.8 7.5 7.0 1 1 7 8 8 8 8 Leucine rich repeat LRR_5 PF13306.6 EKX43303.1 - 4.7e-33 113.9 0.0 1.5e-08 34.7 0.0 3.1 1 1 3 4 4 4 4 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 EKX43303.1 - 1.4e-31 107.9 31.6 1.1e-05 25.6 5.5 8.2 2 2 8 10 10 10 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX43303.1 - 5.3e-15 53.7 24.0 0.34 11.6 0.0 11.4 11 1 0 11 11 11 4 Leucine Rich Repeat LRR_9 PF14580.6 EKX43303.1 - 5e-08 32.6 2.2 0.4 10.2 0.0 4.3 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 EKX43303.1 - 0.00017 21.4 33.6 0.54 10.5 0.9 9.8 10 1 0 10 10 10 3 Leucine Rich repeat LppC PF04348.13 EKX43303.1 - 0.011 14.5 0.3 0.049 12.4 0.0 1.9 2 0 0 2 2 2 0 LppC putative lipoprotein Mito_carr PF00153.27 EKX43306.1 - 1.7e-38 130.4 15.9 6.6e-16 58.0 0.4 4.5 4 1 0 4 4 4 3 Mitochondrial carrier protein Kinesin PF00225.23 EKX43307.1 - 5.2e-76 255.7 6.5 5.7e-75 252.3 6.3 2.5 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX43307.1 - 1.4e-20 73.8 0.2 6.5e-20 71.6 0.1 2.2 1 1 1 2 2 2 1 Microtubule binding DUF4407 PF14362.6 EKX43307.1 - 1.9 7.7 16.1 60 2.8 12.8 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) EGF_3 PF12947.7 EKX43308.1 - 9.7e-08 32.1 8.9 9.7e-08 32.1 8.9 8.8 8 2 2 10 10 10 1 EGF domain cEGF PF12662.7 EKX43308.1 - 1.9e-06 27.7 2.6 1.9e-06 27.7 2.6 10.8 8 3 4 12 12 12 1 Complement Clr-like EGF-like EGF_CA PF07645.15 EKX43308.1 - 2.1e-06 27.8 7.8 2.1e-06 27.8 7.8 9.2 8 2 0 8 8 8 1 Calcium-binding EGF domain Ephrin_rec_like PF07699.13 EKX43308.1 - 2.1e-05 24.2 9.7 5.5e-05 22.9 4.6 9.1 6 2 1 8 8 8 4 Putative ephrin-receptor like TSP_1 PF00090.19 EKX43308.1 - 2.2e-05 24.6 7.3 2.2e-05 24.6 7.3 5.8 4 0 0 4 4 4 2 Thrombospondin type 1 domain hEGF PF12661.7 EKX43308.1 - 0.00036 21.0 1.0 0.00036 21.0 1.0 9.5 12 0 0 12 12 12 1 Human growth factor-like EGF TACC_C PF05010.14 EKX43309.1 - 0.0052 16.6 9.8 0.0052 16.6 9.8 2.0 2 0 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF4735 PF15882.5 EKX43309.1 - 0.028 13.9 7.1 0.023 14.1 5.8 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4735) TPR_MLP1_2 PF07926.12 EKX43309.1 - 0.096 12.7 20.7 0.06 13.4 12.8 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Prp19 PF08606.11 EKX43309.1 - 0.11 12.4 0.3 0.11 12.4 0.3 2.9 3 1 0 3 3 3 0 Prp19/Pso4-like Evr1_Alr PF04777.13 EKX43309.1 - 0.12 12.8 0.3 0.72 10.4 0.0 2.2 2 0 0 2 2 2 0 Erv1 / Alr family Atg14 PF10186.9 EKX43309.1 - 0.13 11.3 6.0 0.17 11.0 6.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PepSY PF03413.19 EKX43309.1 - 0.19 12.3 0.1 0.19 12.3 0.1 2.2 3 0 0 3 3 2 0 Peptidase propeptide and YPEB domain FapA PF03961.13 EKX43309.1 - 0.19 10.3 6.1 0.36 9.4 6.1 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A ubiquitin PF00240.23 EKX43309.1 - 0.23 11.2 2.0 18 5.2 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin family KxDL PF10241.9 EKX43309.1 - 0.25 11.7 13.2 0.23 11.8 6.0 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein OmpH PF03938.14 EKX43309.1 - 0.51 10.7 12.4 0.12 12.7 8.4 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FAM76 PF16046.5 EKX43309.1 - 1 8.7 7.3 1.4 8.2 7.3 1.3 1 0 0 1 1 1 0 FAM76 protein TMPIT PF07851.13 EKX43309.1 - 3.4 6.8 6.4 4.8 6.3 6.4 1.3 1 0 0 1 1 1 0 TMPIT-like protein FlaC_arch PF05377.11 EKX43309.1 - 3.8 8.0 7.9 2.5 8.5 1.5 3.1 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) HIP1_clath_bdg PF16515.5 EKX43309.1 - 4.1 8.1 20.5 0.25 12.0 12.1 2.7 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF883 PF05957.13 EKX43309.1 - 5 7.8 8.6 11 6.7 4.7 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) GIT_CC PF16559.5 EKX43309.1 - 6.7 6.7 10.9 18 5.3 6.0 3.1 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor FUSC PF04632.12 EKX43309.1 - 7.1 5.0 12.0 0.27 9.7 1.4 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family Lectin_N PF03954.14 EKX43309.1 - 8 6.2 9.0 12 5.7 4.2 2.4 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Macro PF01661.21 EKX43314.1 - 2.3e-32 111.5 0.4 9.9e-20 70.8 0.2 2.1 1 1 1 2 2 2 2 Macro domain COMP PF11598.8 EKX43315.1 - 1.2 9.6 8.7 0.97 10.0 0.3 3.7 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein AA_permease_2 PF13520.6 EKX43316.1 - 3.8e-30 105.1 46.0 4.8e-30 104.8 46.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EKX43316.1 - 8e-13 47.8 43.8 1.6e-12 46.8 43.8 1.4 1 1 0 1 1 1 1 Amino acid permease MyTH4 PF00784.17 EKX43317.1 - 0.046 14.2 2.3 0.12 12.8 1.9 1.8 2 0 0 2 2 2 0 MyTH4 domain Macoilin PF09726.9 EKX43317.1 - 0.22 10.0 10.0 0.26 9.8 10.0 1.1 1 0 0 1 1 1 0 Macoilin family TPD52 PF04201.15 EKX43317.1 - 0.32 10.6 7.8 1.3 8.6 6.3 2.4 2 1 1 3 3 3 0 Tumour protein D52 family LMBR1 PF04791.16 EKX43317.1 - 0.34 9.8 2.9 0.39 9.6 2.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SlyX PF04102.12 EKX43317.1 - 0.51 11.0 7.8 0.94 10.1 0.1 3.0 2 1 1 3 3 3 0 SlyX CCDC-167 PF15188.6 EKX43317.1 - 0.62 10.4 8.9 0.083 13.2 0.6 2.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 TMPIT PF07851.13 EKX43317.1 - 1.8 7.8 11.5 0.5 9.6 7.1 1.9 2 0 0 2 2 2 0 TMPIT-like protein YlqD PF11068.8 EKX43317.1 - 6.2 7.2 14.7 2.2 8.6 2.1 2.5 1 1 1 2 2 2 0 YlqD protein Peptidase_S49 PF01343.18 EKX43318.1 - 5.3e-59 198.6 0.0 3.8e-26 91.9 0.0 3.3 3 0 0 3 3 3 3 Peptidase family S49 CLP_protease PF00574.23 EKX43318.1 - 0.0018 18.2 0.2 0.13 12.2 0.1 3.1 3 0 0 3 3 3 1 Clp protease SDH_sah PF01972.16 EKX43318.1 - 0.02 13.9 0.0 0.04 12.9 0.0 1.4 1 0 0 1 1 1 0 Serine dehydrogenase proteinase Arteri_nucleo PF01481.16 EKX43318.1 - 5.2 7.4 5.7 3 8.2 2.7 2.2 2 0 0 2 2 2 0 Arterivirus nucleocapsid protein AA_kinase PF00696.28 EKX43319.1 - 2.2e-38 132.2 2.4 3e-38 131.8 2.4 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 EKX43319.1 - 1.4e-05 24.9 0.0 5e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 PUA domain MADF_DNA_bdg PF10545.9 EKX43320.1 - 0.043 14.1 0.0 0.1 12.9 0.0 1.7 1 1 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like ABC2_membrane_2 PF12679.7 EKX43321.1 - 0.11 11.8 4.5 2.5 7.3 0.0 2.8 2 1 1 3 3 3 0 ABC-2 family transporter protein Cyt_c_ox_IV PF12270.8 EKX43321.1 - 0.12 12.6 3.6 0.59 10.3 0.1 2.6 1 1 1 2 2 2 0 Cytochrome c oxidase subunit IV ASD2 PF08687.11 EKX43321.1 - 0.22 11.0 1.8 0.29 10.7 1.8 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Phage_holin_Dp1 PF16938.5 EKX43321.1 - 1.9 8.8 4.7 2.6 8.3 3.1 1.9 2 0 0 2 2 2 0 Putative phage holin Dp-1 PH PF00169.29 EKX43323.1 - 9.8e-09 35.7 0.1 1.5e-08 35.1 0.1 1.3 1 0 0 1 1 1 1 PH domain U-box PF04564.15 EKX43325.1 - 7.2e-15 54.9 0.0 1.3e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 U-box domain TerY_C PF15616.6 EKX43325.1 - 0.012 15.7 9.0 0.012 15.7 9.0 2.6 1 1 1 2 2 2 0 TerY-C metal binding domain zf-Nse PF11789.8 EKX43325.1 - 0.018 14.9 0.0 0.018 14.9 0.0 2.8 3 1 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 EKX43325.1 - 0.034 14.3 0.0 0.079 13.1 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zinc_ribbon_12 PF11331.8 EKX43325.1 - 0.06 13.2 0.2 0.06 13.2 0.2 4.3 2 1 3 5 5 5 0 Probable zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 EKX43325.1 - 0.28 11.2 6.9 9.9 6.2 0.1 2.7 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf_C2H2_10 PF18414.1 EKX43325.1 - 0.35 10.4 6.7 1 8.9 0.1 3.4 3 0 0 3 3 3 0 C2H2 type zinc-finger IBR PF01485.21 EKX43325.1 - 0.55 10.5 15.4 6.8 7.0 0.2 3.5 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain HypA PF01155.19 EKX43325.1 - 0.62 10.1 15.2 0.76 9.8 3.8 3.5 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA OrfB_Zn_ribbon PF07282.11 EKX43325.1 - 5.1 7.1 12.2 17 5.4 0.8 4.2 3 1 1 4 4 4 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.10 EKX43325.1 - 7.4 6.8 15.4 0.1 12.7 1.0 3.7 3 0 0 3 3 3 0 Zinc ribbon domain MRP-L28 PF09812.9 EKX43326.1 - 0.0086 16.2 1.3 0.011 15.8 1.3 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Sec2p PF06428.11 EKX43326.1 - 0.03 14.3 4.4 0.044 13.7 4.4 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Cytochrom_C PF00034.21 EKX43326.1 - 0.035 15.2 0.3 0.061 14.5 0.3 1.4 1 0 0 1 1 1 0 Cytochrome c CH_2 PF06294.11 EKX43327.1 - 1.2e-15 57.3 0.0 3.9e-15 55.7 0.0 1.9 2 0 0 2 2 2 1 CH-like domain in sperm protein ADK PF00406.22 EKX43327.1 - 4.1e-11 43.2 0.0 1.7e-09 38.0 0.0 3.0 2 0 0 2 2 2 1 Adenylate kinase AAA_17 PF13207.6 EKX43327.1 - 0.0023 18.4 16.0 0.029 14.8 0.0 5.0 4 0 0 4 4 4 2 AAA domain Hydin_ADK PF17213.3 EKX43327.1 - 0.0048 17.2 0.2 0.0048 17.2 0.2 4.4 5 0 0 5 5 5 1 Hydin Adenylate kinase-like domain DUF3474 PF11960.8 EKX43327.1 - 0.37 11.0 1.4 2.7 8.2 1.0 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3474) Sulfotransfer_2 PF03567.14 EKX43328.1 - 1.7e-10 41.3 0.0 6.7e-08 32.7 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase family HLH PF00010.26 EKX43329.1 - 5.1e-13 48.8 0.6 5.1e-13 48.8 0.6 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain ASFV_J13L PF05568.11 EKX43329.1 - 1.5 8.5 5.7 2.2 8.0 5.7 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein Abhydrolase_1 PF00561.20 EKX43330.1 - 2.1e-19 70.2 0.0 2.3e-18 66.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EKX43330.1 - 3.2e-11 44.3 0.0 3.2e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EKX43330.1 - 2.7e-10 39.9 0.3 3.8e-10 39.5 0.3 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 EKX43330.1 - 0.053 12.2 0.0 0.071 11.8 0.0 1.2 1 0 0 1 1 1 0 Ndr family Ser_hydrolase PF06821.13 EKX43330.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.4 2 0 0 2 2 2 0 Serine hydrolase LBR_tudor PF09465.10 EKX43331.1 - 0.056 13.2 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain DUF1918 PF08940.11 EKX43331.1 - 0.34 10.5 0.1 0.34 10.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) Cupin_8 PF13621.6 EKX43332.1 - 6.5e-14 52.3 0.7 2.2e-13 50.5 0.3 2.1 2 1 0 2 2 2 1 Cupin-like domain JmjC PF02373.22 EKX43332.1 - 5.6e-11 42.9 0.1 1.7e-10 41.3 0.1 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase DUF268 PF03269.14 EKX43332.1 - 0.016 15.1 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF268 dTDP_sugar_isom PF00908.17 EKX43332.1 - 0.08 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase DUF2470 PF10615.9 EKX43334.1 - 3.6e-11 43.5 0.0 4.2e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) SPA PF08616.10 EKX43334.1 - 0.18 11.8 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis UPF0016 PF01169.19 EKX43336.1 - 8.7e-45 150.9 16.6 9.3e-23 80.4 3.4 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 PrsW-protease PF13367.6 EKX43336.1 - 0.025 14.0 2.7 0.025 14.0 2.7 1.8 2 0 0 2 2 2 0 PrsW family intramembrane metalloprotease DUF3995 PF13160.6 EKX43336.1 - 0.3 11.5 8.2 0.96 9.8 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) RWP-RK PF02042.15 EKX43337.1 - 2.8e-14 52.8 0.1 6e-14 51.7 0.0 1.6 2 0 0 2 2 2 1 RWP-RK domain DHC_N2 PF08393.13 EKX43338.1 - 6.8e-108 361.3 9.7 6.8e-108 361.3 9.7 2.4 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 EKX43338.1 - 8.8e-98 327.3 0.0 1.9e-54 184.8 0.1 3.1 2 1 1 3 3 3 2 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 EKX43338.1 - 1.1e-97 326.5 0.1 1e-96 323.3 0.0 2.5 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EKX43338.1 - 4.9e-83 277.6 5.9 2.1e-82 275.5 5.6 2.2 2 0 0 2 2 2 1 ATP-binding dynein motor region MT PF12777.7 EKX43338.1 - 8.6e-78 261.8 12.0 6.5e-76 255.6 15.0 2.2 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 EKX43338.1 - 2.9e-77 259.9 0.0 5.9e-77 258.9 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 EKX43338.1 - 2.3e-66 222.7 0.4 2.8e-62 209.4 0.0 4.1 4 0 0 4 4 4 1 P-loop containing dynein motor region Kelch_4 PF13418.6 EKX43338.1 - 6.4e-45 150.9 15.2 1.6e-05 24.8 0.2 10.4 10 0 0 10 10 10 7 Galactose oxidase, central domain Kelch_5 PF13854.6 EKX43338.1 - 1.7e-38 130.0 2.4 1.1e-05 25.2 0.1 10.9 11 0 0 11 11 11 6 Kelch motif AAA_lid_11 PF18198.1 EKX43338.1 - 1.5e-37 129.0 0.1 2.4e-36 125.0 0.0 2.7 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EKX43338.1 - 1.6e-35 121.8 0.3 1e-32 112.7 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Kelch_3 PF13415.6 EKX43338.1 - 4.5e-33 112.9 3.6 1.1e-06 28.8 0.1 10.4 10 0 0 10 10 10 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EKX43338.1 - 3.1e-28 97.1 1.1 0.00026 21.2 0.0 9.5 9 0 0 9 9 9 5 Kelch motif AAA_lid_1 PF17857.1 EKX43338.1 - 3.1e-24 85.1 0.6 3.1e-24 85.1 0.6 2.6 3 0 0 3 3 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 EKX43338.1 - 6.4e-24 84.5 0.9 6.4e-24 84.5 0.9 2.5 3 0 0 3 3 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EKX43338.1 - 1.3e-15 57.6 0.0 4.1e-07 30.1 0.0 5.0 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) Kelch_1 PF01344.25 EKX43338.1 - 3.1e-15 55.5 21.2 0.00061 19.3 0.0 9.2 11 0 0 11 11 10 5 Kelch motif Kelch_2 PF07646.15 EKX43338.1 - 1.2e-14 53.5 15.7 0.26 11.3 0.0 9.4 9 0 0 9 9 8 5 Kelch motif Filamin PF00630.19 EKX43338.1 - 1.7e-12 48.0 0.0 4.8e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 Filamin/ABP280 repeat AAA_22 PF13401.6 EKX43338.1 - 5.4e-05 23.5 0.0 2 8.7 0.0 4.6 4 0 0 4 4 4 1 AAA domain Sporozoite_P67 PF05642.11 EKX43338.1 - 7.3e-05 21.1 6.8 0.00012 20.4 6.8 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen AAA_18 PF13238.6 EKX43338.1 - 0.0012 19.4 0.6 5.1 7.7 0.0 4.4 4 0 0 4 4 4 1 AAA domain ABC_tran PF00005.27 EKX43338.1 - 0.0013 19.3 0.1 1.2 9.6 0.0 4.2 3 0 0 3 3 3 1 ABC transporter TIG PF01833.24 EKX43338.1 - 0.0049 16.9 0.1 0.013 15.5 0.1 1.8 1 0 0 1 1 1 1 IPT/TIG domain AAA_16 PF13191.6 EKX43338.1 - 0.0062 16.9 0.5 2.5 8.5 0.0 4.3 4 0 0 4 4 4 1 AAA ATPase domain YjcZ PF13990.6 EKX43338.1 - 0.11 11.8 0.3 0.29 10.5 0.3 1.6 1 0 0 1 1 1 0 YjcZ-like protein PTS-HPr PF00381.19 EKX43338.1 - 0.13 12.5 0.4 2.4 8.5 0.1 2.7 2 0 0 2 2 2 0 PTS HPr component phosphorylation site AAA_28 PF13521.6 EKX43338.1 - 0.13 12.5 0.0 17 5.6 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EKX43338.1 - 0.28 10.9 4.9 19 4.9 0.0 3.7 4 0 0 4 4 3 0 AAA domain DUF948 PF06103.11 EKX43338.1 - 2.5 8.4 8.3 17 5.7 1.1 4.4 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) AAA PF00004.29 EKX43338.1 - 2.6 8.5 4.7 19 5.7 0.0 4.2 5 1 0 5 5 3 0 ATPase family associated with various cellular activities (AAA) Methyltransf_21 PF05050.12 EKX43339.1 - 3.4e-05 23.9 0.1 0.00013 22.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase FkbM domain SelP_N PF04592.14 EKX43339.1 - 0.18 11.1 10.9 0.28 10.5 10.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Sporozoite_P67 PF05642.11 EKX43339.1 - 0.46 8.5 5.4 0.53 8.3 5.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF5568 PF17724.1 EKX43339.1 - 0.51 10.1 4.7 0.8 9.5 4.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5568) PAS_9 PF13426.7 EKX43341.1 - 0.00037 20.7 0.0 0.00061 20.0 0.0 1.3 1 0 0 1 1 1 1 PAS domain Tho2 PF11262.8 EKX43343.1 - 1.1e-06 28.0 9.9 1.9e-06 27.3 9.9 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Desmo_N PF06771.11 EKX43343.1 - 0.00014 22.2 2.6 0.42 11.0 0.1 3.3 1 1 2 3 3 3 1 Viral Desmoplakin N-terminus GAS PF13851.6 EKX43343.1 - 0.00015 21.2 18.7 0.00026 20.4 18.7 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 EKX43343.1 - 0.00054 20.0 35.0 0.0049 16.9 10.4 2.3 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein OmpH PF03938.14 EKX43343.1 - 0.0011 19.4 18.6 0.0012 19.2 17.1 1.8 2 0 0 2 2 1 1 Outer membrane protein (OmpH-like) Baculo_PEP_C PF04513.12 EKX43343.1 - 0.0041 17.2 4.3 0.011 15.8 3.8 1.9 2 0 0 2 2 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4515 PF14988.6 EKX43343.1 - 0.0042 16.9 25.7 0.015 15.1 25.7 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4515) YvrJ PF12841.7 EKX43343.1 - 0.0054 16.2 5.6 3 7.5 0.1 3.8 3 0 0 3 3 3 0 YvrJ protein family DUF3584 PF12128.8 EKX43343.1 - 0.01 13.4 16.3 0.016 12.7 16.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FlxA PF14282.6 EKX43343.1 - 0.011 15.8 29.0 0.55 10.2 10.2 3.0 1 1 1 2 2 2 0 FlxA-like protein Phage_GP20 PF06810.11 EKX43343.1 - 0.011 15.5 21.4 0.032 14.0 11.1 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 Golgin_A5 PF09787.9 EKX43343.1 - 0.012 15.1 15.9 0.018 14.5 15.9 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 V_ATPase_I PF01496.19 EKX43343.1 - 0.012 13.6 6.1 0.016 13.2 6.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 EKX43343.1 - 0.017 14.0 14.8 0.029 13.3 14.8 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein SHE3 PF17078.5 EKX43343.1 - 0.019 14.7 22.9 0.038 13.7 10.3 2.7 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Arfaptin PF06456.13 EKX43343.1 - 0.022 14.4 10.1 0.05 13.2 10.1 1.6 1 0 0 1 1 1 0 Arfaptin-like domain BRX_N PF13713.6 EKX43343.1 - 0.026 14.3 0.6 0.067 13.0 0.6 1.6 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain DUF948 PF06103.11 EKX43343.1 - 0.032 14.5 6.5 0.13 12.6 0.9 2.8 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) Nup54_57_C PF18570.1 EKX43343.1 - 0.043 13.4 20.1 0.47 10.1 3.2 4.4 3 1 1 4 4 4 0 NUP57/Nup54 C-terminal domain Syntaxin-6_N PF09177.11 EKX43343.1 - 0.06 13.9 13.3 1.7 9.3 14.0 2.8 2 1 0 2 2 1 0 Syntaxin 6, N-terminal Tup_N PF08581.10 EKX43343.1 - 0.065 13.5 18.9 0.11 12.8 10.7 2.9 1 1 2 3 3 3 0 Tup N-terminal FapA PF03961.13 EKX43343.1 - 0.086 11.4 13.0 0.14 10.7 13.0 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A MatP_C PF17414.2 EKX43343.1 - 0.087 13.0 12.0 2.3 8.5 1.7 3.9 1 1 2 3 3 3 0 MatP C-terminal ribbon-helix-helix domain Exonuc_VII_L PF02601.15 EKX43343.1 - 0.13 11.8 15.0 0.45 10.0 15.0 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit TMPIT PF07851.13 EKX43343.1 - 0.14 11.4 15.6 1.1 8.5 15.7 2.1 1 1 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 EKX43343.1 - 0.16 11.3 12.6 0.29 10.5 12.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4410 PF14366.6 EKX43343.1 - 0.17 11.8 1.9 0.36 10.8 1.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4410) FAM184 PF15665.5 EKX43343.1 - 0.19 11.5 18.8 0.13 12.0 16.1 2.0 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B HHV-5_US34A PF17087.5 EKX43343.1 - 0.26 11.4 10.1 0.52 10.5 0.4 3.4 1 1 2 3 3 3 0 Herpesvirus US34A protein family Hema_stalk PF08720.10 EKX43343.1 - 0.27 10.9 2.3 0.67 9.6 1.5 1.9 1 1 1 2 2 2 0 Influenza C hemagglutinin stalk SYF2 PF08231.12 EKX43343.1 - 0.3 11.5 14.6 2 8.8 3.8 2.8 1 1 2 3 3 3 0 SYF2 splicing factor Csm1_N PF18504.1 EKX43343.1 - 0.36 11.2 18.4 0.58 10.5 5.2 3.7 1 1 2 3 3 3 0 Csm1 N-terminal domain ACCA PF03255.14 EKX43343.1 - 0.36 10.7 13.1 0.28 11.1 4.0 2.8 2 1 1 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Transposase_1 PF01359.18 EKX43343.1 - 0.57 10.1 4.6 11 6.0 0.2 3.2 1 1 2 3 3 3 0 Transposase (partial DDE domain) DUF3087 PF11286.8 EKX43343.1 - 0.58 9.6 4.9 0.43 10.0 2.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3087) ApoO PF09769.9 EKX43343.1 - 0.87 9.5 2.5 2.5 8.1 1.1 2.3 1 1 1 2 2 2 0 Apolipoprotein O ERM PF00769.19 EKX43343.1 - 0.89 9.3 19.4 2.5 7.8 19.4 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF148 PF02520.17 EKX43343.1 - 1 9.5 15.8 2.1 8.5 9.0 2.6 1 1 1 2 2 2 0 Domain of unknown function DUF148 LMBR1 PF04791.16 EKX43343.1 - 1.5 7.6 7.5 2 7.2 7.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein YscO-like PF16789.5 EKX43343.1 - 1.6 8.8 18.0 1.8 8.6 7.3 2.2 1 1 1 2 2 2 0 YscO-like protein ZYG-11_interact PF05884.12 EKX43343.1 - 1.7 8.0 6.1 9.6 5.5 6.0 2.1 1 1 0 1 1 1 0 Interactor of ZYG-11 CotJB PF12652.7 EKX43343.1 - 1.7 8.9 4.9 15 5.9 0.4 3.2 2 1 2 4 4 3 0 CotJB protein LPP PF04728.13 EKX43343.1 - 1.8 9.0 17.0 6.9 7.2 2.9 3.9 1 1 1 2 2 2 0 Lipoprotein leucine-zipper DUF4200 PF13863.6 EKX43343.1 - 1.8 8.9 27.7 14 6.1 5.4 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Atg14 PF10186.9 EKX43343.1 - 2.2 7.3 15.1 3.5 6.6 15.1 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Jnk-SapK_ap_N PF09744.9 EKX43343.1 - 2.2 8.5 19.4 4.3 7.5 18.2 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 HisKA PF00512.25 EKX43343.1 - 2.2 8.4 0.0 2.2 8.4 0.0 3.5 2 1 0 2 2 1 0 His Kinase A (phospho-acceptor) domain HMMR_N PF15905.5 EKX43343.1 - 2.4 7.6 21.9 19 4.6 21.9 2.4 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal TMF_TATA_bd PF12325.8 EKX43343.1 - 2.6 8.3 20.3 1.4 9.1 13.8 3.0 2 1 2 4 4 3 0 TATA element modulatory factor 1 TATA binding Fib_alpha PF08702.10 EKX43343.1 - 2.6 8.2 22.6 4.7 7.4 0.5 2.5 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family Mt_ATP-synt_D PF05873.12 EKX43343.1 - 3.1 7.6 10.9 63 3.4 11.2 2.6 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DUF87 PF01935.17 EKX43343.1 - 3.3 7.7 11.4 26 4.8 12.3 2.0 2 1 0 2 2 2 0 Helicase HerA, central domain DUF1640 PF07798.11 EKX43343.1 - 3.9 7.5 17.5 7.4 6.6 17.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF4633 PF15464.6 EKX43343.1 - 4.3 7.5 7.8 3.1 8.0 0.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4633) YtxH PF12732.7 EKX43343.1 - 4.7 7.8 8.4 2.4e+02 2.4 8.5 2.6 1 1 0 1 1 1 0 YtxH-like protein DIT1_PvcA PF05141.12 EKX43343.1 - 5.5 6.4 10.1 5.3 6.4 8.9 1.4 1 1 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein YlqD PF11068.8 EKX43343.1 - 6.6 7.1 20.6 11 6.4 17.2 2.5 1 1 1 2 2 2 0 YlqD protein Phage_Mu_Gam PF07352.12 EKX43343.1 - 6.7 6.6 17.2 21 5.0 7.2 2.6 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein DUF883 PF05957.13 EKX43343.1 - 6.9 7.3 8.0 51 4.6 5.6 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) SlyX PF04102.12 EKX43343.1 - 7.2 7.3 20.3 2.6 8.7 6.0 3.8 1 1 2 3 3 3 0 SlyX Nsp1_C PF05064.13 EKX43343.1 - 8.3 6.3 18.3 2.3 8.1 3.3 3.7 1 1 1 2 2 2 0 Nsp1-like C-terminal region MRPL52 PF18699.1 EKX43343.1 - 8.6 6.6 15.2 10 6.4 4.6 2.9 2 1 1 3 3 2 0 Mitoribosomal protein mL52 CENP-Q PF13094.6 EKX43343.1 - 9.4 6.4 17.9 80 3.4 17.9 2.1 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Herpes_UL6 PF01763.16 EKX43343.1 - 9.7 4.6 12.5 28 3.1 12.4 1.7 1 1 0 1 1 1 0 Herpesvirus UL6 like PIH1 PF08190.12 EKX43346.1 - 5.7e-20 71.4 0.1 1.7e-19 69.9 0.1 1.7 1 1 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 EKX43346.1 - 8.6e-10 38.9 0.0 1.6e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 PIH1 CS-like domain DUF2796 PF10986.8 EKX43347.1 - 0.0067 16.4 0.7 0.014 15.3 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2796) CENP-B_dimeris PF09026.10 EKX43347.1 - 0.0071 16.7 9.9 0.0071 16.7 9.9 2.2 3 0 0 3 3 3 1 Centromere protein B dimerisation domain DUF3295 PF11702.8 EKX43347.1 - 0.34 10.2 5.2 0.45 9.8 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) TFB6 PF17110.5 EKX43347.1 - 0.97 9.2 4.3 3 7.6 4.2 1.8 1 1 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Ebp2 PF05890.12 EKX43348.1 - 0.0044 16.6 0.2 0.0072 15.9 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 GIT_CC PF16559.5 EKX43348.1 - 0.0096 15.8 0.9 0.017 15.0 0.9 1.4 1 0 0 1 1 1 1 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2205 PF10224.9 EKX43348.1 - 0.091 12.8 0.4 0.18 11.8 0.4 1.4 1 0 0 1 1 1 0 Short coiled-coil protein Cep57_CLD_2 PF14197.6 EKX43348.1 - 0.23 11.6 3.2 0.42 10.7 2.8 1.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 MAPEG PF01124.18 EKX43349.1 - 1.5e-21 76.6 0.4 1.9e-21 76.3 0.4 1.1 1 0 0 1 1 1 1 MAPEG family Ank_2 PF12796.7 EKX43350.1 - 3.6e-25 88.4 0.4 2e-16 60.3 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX43350.1 - 1.2e-17 64.0 0.1 3.7e-08 33.8 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX43350.1 - 4.4e-16 57.3 0.0 0.00015 21.9 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EKX43350.1 - 5.8e-14 52.0 0.2 9.5e-08 32.2 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX43350.1 - 2e-12 46.9 0.0 2.2e-05 24.7 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat zf-RING_11 PF17123.5 EKX43351.1 - 3.1e-05 23.6 0.5 7.5e-05 22.4 0.5 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EKX43351.1 - 0.00042 20.3 0.3 0.00085 19.3 0.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EKX43351.1 - 0.00058 20.1 0.3 0.00058 20.1 0.3 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX43351.1 - 0.0041 16.9 0.5 0.01 15.7 0.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX43351.1 - 0.0053 16.6 0.6 0.012 15.5 0.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EKX43351.1 - 0.0062 16.4 0.4 0.016 15.0 0.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX43351.1 - 0.13 12.3 0.6 0.26 11.3 0.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DNA_pol_phi PF04931.13 EKX43352.1 - 5.9e-121 405.0 36.0 5.9e-121 405.0 36.0 1.9 2 0 0 2 2 2 1 DNA polymerase phi BUD22 PF09073.10 EKX43352.1 - 3.7e-06 26.6 25.0 3.7e-06 26.6 25.0 2.2 2 0 0 2 2 2 1 BUD22 SDA1 PF05285.12 EKX43352.1 - 5e-05 22.9 29.6 0.00014 21.4 29.6 1.7 1 0 0 1 1 1 1 SDA1 ORC5_C PF14630.6 EKX43352.1 - 0.0004 20.0 0.1 0.0012 18.4 0.1 1.8 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus Tim54 PF11711.8 EKX43352.1 - 0.089 11.6 5.0 0.2 10.4 5.0 1.6 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2457 PF10446.9 EKX43352.1 - 0.19 10.8 50.3 0.47 9.5 50.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SAPS PF04499.15 EKX43352.1 - 0.22 10.3 10.3 0.48 9.2 9.8 1.8 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 EKX43352.1 - 0.23 9.7 29.1 0.53 8.5 29.1 1.5 1 0 0 1 1 1 0 CDC45-like protein Pep1_7 PF17232.2 EKX43352.1 - 0.45 11.0 0.1 0.45 11.0 0.1 5.8 5 1 1 6 6 5 0 Elicitor peptide 1-7 eIF-3c_N PF05470.12 EKX43352.1 - 4.9 5.4 21.6 13 3.9 21.6 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Nop14 PF04147.12 EKX43352.1 - 5.1 5.2 51.6 0.2 9.8 38.9 2.5 3 0 0 3 3 3 0 Nop14-like family Merozoite_SPAM PF07133.11 EKX43352.1 - 7 6.6 48.6 8.2 6.4 45.5 2.3 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) CKS PF01111.19 EKX43355.1 - 7.2e-38 128.7 0.8 8.8e-38 128.4 0.8 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF3253 PF11625.8 EKX43355.1 - 0.16 12.2 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) PPR_1 PF12854.7 EKX43356.1 - 2e-22 78.6 0.0 4.2e-07 29.5 0.0 3.5 3 1 0 3 3 3 3 PPR repeat PPR_2 PF13041.6 EKX43356.1 - 4e-21 75.0 0.0 5.8e-15 55.2 0.0 2.5 2 1 0 2 2 2 2 PPR repeat family PPR_3 PF13812.6 EKX43356.1 - 2.3e-17 62.8 0.0 1.7e-09 37.6 0.0 2.1 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR PF01535.20 EKX43356.1 - 2e-15 55.9 0.3 2.1e-07 30.7 0.0 3.3 3 0 0 3 3 3 3 PPR repeat PPR_long PF17177.4 EKX43356.1 - 0.00016 21.1 0.0 0.00025 20.5 0.0 1.3 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP Stm1_N PF09598.10 EKX43359.1 - 7.9 7.4 6.7 3.9 8.4 3.6 2.1 2 0 0 2 2 2 0 Stm1 PARP_regulatory PF01358.18 EKX43363.1 - 1.2e-19 70.3 0.0 1.5e-19 70.1 0.0 1.0 1 0 0 1 1 1 1 Poly A polymerase regulatory subunit Spc7 PF08317.11 EKX43365.1 - 6.8e-07 28.5 2.6 3.7e-06 26.0 2.6 1.9 1 1 0 1 1 1 1 Spc7 kinetochore protein FlaC_arch PF05377.11 EKX43365.1 - 1.9e-05 24.9 5.2 0.036 14.4 0.0 3.7 2 2 1 3 3 3 2 Flagella accessory protein C (FlaC) DUF812 PF05667.11 EKX43365.1 - 2.2e-05 23.6 8.1 0.0026 16.7 0.8 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF812) Laminin_II PF06009.12 EKX43365.1 - 3.8e-05 23.7 0.4 0.00043 20.3 0.1 2.2 1 1 1 2 2 2 1 Laminin Domain II NPV_P10 PF05531.12 EKX43365.1 - 5.3e-05 23.6 2.1 0.13 12.8 0.4 3.0 1 1 1 2 2 2 2 Nucleopolyhedrovirus P10 protein Laminin_I PF06008.14 EKX43365.1 - 6.8e-05 22.7 0.8 9.9e-05 22.2 0.8 1.3 1 0 0 1 1 1 1 Laminin Domain I ATG16 PF08614.11 EKX43365.1 - 9.2e-05 22.8 0.5 0.00026 21.3 0.4 1.9 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) Myosin_tail_1 PF01576.19 EKX43365.1 - 0.00011 20.2 3.6 0.00011 20.2 3.6 2.0 1 1 1 2 2 2 1 Myosin tail DUF1664 PF07889.12 EKX43365.1 - 0.00016 21.7 6.4 0.0061 16.6 0.7 2.4 1 1 2 3 3 3 2 Protein of unknown function (DUF1664) Phage_GP20 PF06810.11 EKX43365.1 - 0.00035 20.4 2.3 0.015 15.1 2.3 2.4 1 1 0 1 1 1 1 Phage minor structural protein GP20 DUF5082 PF16888.5 EKX43365.1 - 0.00039 20.7 8.7 0.033 14.5 4.2 3.4 1 1 1 2 2 2 1 Domain of unknown function (DUF5082) Fez1 PF06818.15 EKX43365.1 - 0.00079 19.9 5.3 0.0023 18.4 0.1 2.1 1 1 1 2 2 2 1 Fez1 Filament PF00038.21 EKX43365.1 - 0.00084 19.0 4.9 0.0023 17.6 0.3 2.1 1 1 0 2 2 2 1 Intermediate filament protein CENP-F_leu_zip PF10473.9 EKX43365.1 - 0.0011 19.1 2.8 0.011 15.7 0.1 2.6 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PhageMin_Tail PF10145.9 EKX43365.1 - 0.0011 18.9 0.8 0.62 9.9 0.8 2.9 1 1 0 1 1 1 1 Phage-related minor tail protein DHR10 PF18595.1 EKX43365.1 - 0.0019 18.2 0.8 0.089 12.9 0.0 2.7 1 1 1 2 2 2 1 Designed helical repeat protein 10 domain COG2 PF06148.11 EKX43365.1 - 0.0028 17.8 2.1 0.04 14.0 0.8 2.5 1 1 1 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 AAA_13 PF13166.6 EKX43365.1 - 0.003 16.3 1.6 0.088 11.4 0.2 2.1 1 1 1 2 2 2 1 AAA domain FliJ PF02050.16 EKX43365.1 - 0.003 17.8 0.5 0.013 15.8 0.0 2.1 1 1 1 2 2 2 1 Flagellar FliJ protein DASH_Duo1 PF08651.10 EKX43365.1 - 0.0033 17.1 0.1 3.8 7.4 0.0 3.5 1 1 2 3 3 3 0 DASH complex subunit Duo1 FPP PF05911.11 EKX43365.1 - 0.0039 15.5 3.0 0.0048 15.2 3.0 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil IFT57 PF10498.9 EKX43365.1 - 0.0052 15.8 4.5 0.0094 15.0 4.5 1.4 1 1 0 1 1 1 1 Intra-flagellar transport protein 57 DUF4795 PF16043.5 EKX43365.1 - 0.0059 16.2 2.1 0.066 12.8 2.1 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) UPF0242 PF06785.11 EKX43365.1 - 0.0075 16.4 4.1 0.012 15.7 0.5 2.3 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0242) N-terminus Bacillus_HBL PF05791.11 EKX43365.1 - 0.0078 16.1 7.3 1.5 8.6 0.8 3.3 1 1 2 3 3 3 2 Bacillus haemolytic enterotoxin (HBL) EzrA PF06160.12 EKX43365.1 - 0.0093 14.2 0.6 0.013 13.7 0.6 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Prefoldin_2 PF01920.20 EKX43365.1 - 0.0096 15.9 8.4 0.078 12.9 0.7 3.2 1 1 1 2 2 2 2 Prefoldin subunit Tropomyosin_1 PF12718.7 EKX43365.1 - 0.014 15.6 4.4 0.018 15.2 0.7 2.4 1 1 1 2 2 2 0 Tropomyosin like TMPIT PF07851.13 EKX43365.1 - 0.017 14.4 4.1 0.018 14.3 0.7 1.9 2 0 0 2 2 2 0 TMPIT-like protein MtrG PF04210.13 EKX43365.1 - 0.018 14.9 2.1 3.6 7.5 0.4 2.7 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G efThoc1 PF11957.8 EKX43365.1 - 0.021 13.5 0.1 0.021 13.5 0.1 1.9 2 0 0 2 2 2 0 THO complex subunit 1 transcription elongation factor DUF4349 PF14257.6 EKX43365.1 - 0.021 14.3 3.9 10 5.5 0.0 3.6 1 1 4 5 5 5 0 Domain of unknown function (DUF4349) HrpB7 PF09486.10 EKX43365.1 - 0.024 15.0 0.3 1.1 9.6 0.0 2.3 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Baculo_PEP_C PF04513.12 EKX43365.1 - 0.029 14.4 0.0 0.086 12.9 0.0 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TolA_bind_tri PF16331.5 EKX43365.1 - 0.032 14.3 0.7 0.032 14.3 0.7 3.6 1 1 2 3 3 3 0 TolA binding protein trimerisation DUF948 PF06103.11 EKX43365.1 - 0.049 13.9 2.3 3.3 8.0 0.7 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2312 PF10073.9 EKX43365.1 - 0.089 12.4 12.2 6.3 6.5 2.1 4.1 2 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2312) UPF0561 PF10573.9 EKX43365.1 - 0.14 12.3 2.1 0.21 11.7 2.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 DUF4715 PF15835.5 EKX43365.1 - 0.15 12.1 5.4 3.6 7.7 0.6 3.4 1 1 1 3 3 3 0 Domain of unknown function (DUF4715) TssO PF17561.2 EKX43365.1 - 0.25 11.4 1.9 0.46 10.6 0.5 1.9 1 1 1 2 2 2 0 Type VI secretion system, TssO PEARLI-4 PF05278.12 EKX43365.1 - 0.27 10.8 4.6 0.3 10.6 0.5 2.3 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) DivIC PF04977.15 EKX43365.1 - 0.27 11.0 4.1 1.6 8.5 0.8 3.1 1 1 3 4 4 4 0 Septum formation initiator TACC_C PF05010.14 EKX43365.1 - 0.46 10.3 8.8 0.75 9.5 2.9 2.2 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal HsbA PF12296.8 EKX43365.1 - 0.46 10.9 3.0 1.7 9.1 3.0 2.0 1 1 0 1 1 1 0 Hydrophobic surface binding protein A ParB PF08775.10 EKX43365.1 - 0.76 10.3 6.2 2 8.9 3.4 2.8 1 1 0 2 2 2 0 ParB family DUF2203 PF09969.9 EKX43365.1 - 0.83 10.4 8.6 49 4.7 7.7 2.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Coa1 PF08695.10 EKX43365.1 - 1.2 8.9 8.6 2.6 7.8 1.5 2.7 1 1 1 2 2 2 0 Cytochrome oxidase complex assembly protein 1 FAM76 PF16046.5 EKX43365.1 - 2.1 7.6 5.9 2.7 7.3 5.9 1.3 1 0 0 1 1 1 0 FAM76 protein RHSP PF07999.11 EKX43367.1 - 0.0023 16.8 0.1 0.013 14.4 0.0 1.9 1 1 1 2 2 2 1 Retrotransposon hot spot protein IstB_IS21 PF01695.17 EKX43367.1 - 0.0075 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EKX43367.1 - 0.031 13.7 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MeaB PF03308.16 EKX43367.1 - 0.043 12.8 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 EKX43367.1 - 0.064 13.7 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 EKX43367.1 - 0.1 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 KaiC NucS PF01939.16 EKX43368.1 - 0.059 12.7 0.0 0.25 10.7 0.0 1.9 1 1 0 1 1 1 0 Endonuclease NucS Bin3 PF06859.12 EKX43368.1 - 0.066 13.8 0.0 7.2 7.3 0.0 2.1 2 0 0 2 2 2 0 Bicoid-interacting protein 3 (Bin3) Sigma70_r1_1 PF03979.14 EKX43368.1 - 0.13 12.4 0.0 22 5.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 Phycoerythr_ab PF02972.14 EKX43370.1 - 4.1e-17 61.7 0.0 5.9e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Phycoerythrin, alpha/beta chain Proteasome PF00227.26 EKX43371.1 - 1.1e-48 165.2 0.1 1.4e-48 164.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit TauE PF01925.19 EKX43372.1 - 8.7e-17 61.5 28.3 3.3e-10 40.0 1.7 2.5 2 1 1 3 3 3 2 Sulfite exporter TauE/SafE CitMHS PF03600.16 EKX43372.1 - 0.059 12.6 19.4 0.048 12.8 1.0 2.5 2 0 0 2 2 2 0 Citrate transporter Neuroparsin PF07327.11 EKX43372.1 - 0.93 10.0 5.1 3.2 8.2 3.0 2.3 2 0 0 2 2 2 0 Neuroparsin Adap_comp_sub PF00928.21 EKX43373.1 - 4.3e-89 298.4 0.0 5.5e-89 298.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EKX43373.1 - 4.3e-07 30.0 0.9 7.2e-07 29.2 0.9 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EKX43373.1 - 9.5e-05 22.0 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain CTU2 PF10288.9 EKX43374.1 - 0.00096 19.4 0.4 1.1 9.5 0.2 2.6 2 1 0 2 2 2 2 Cytoplasmic tRNA 2-thiolation protein 2 MORN PF02493.20 EKX43375.1 - 2.9e-51 168.4 51.5 2.1e-08 33.5 1.4 8.3 8 0 0 8 8 8 8 MORN repeat SM-ATX PF14438.6 EKX43375.1 - 0.52 10.5 2.2 48 4.2 0.0 3.8 5 0 0 5 5 5 0 Ataxin 2 SM domain CAP_N PF01213.19 EKX43375.1 - 2.2 7.7 5.3 3.1 7.2 5.3 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Zn_clus PF00172.18 EKX43378.1 - 1.1e-06 28.6 12.5 2e-06 27.8 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ORC5_C PF14630.6 EKX43379.1 - 0.006 16.1 0.6 0.024 14.2 0.2 1.9 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus Neisseria_TspB PF05616.13 EKX43380.1 - 0.92 7.9 4.1 1.7 7.1 4.1 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Oxidored_FMN PF00724.20 EKX43381.1 - 8.6e-83 278.4 0.0 1.2e-82 277.9 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 EKX43381.1 - 5.1e-26 91.6 6.0 8.6e-26 90.8 6.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EKX43381.1 - 3.6e-10 39.9 0.9 1.5e-09 37.9 0.0 2.5 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EKX43381.1 - 5.5e-10 39.7 5.7 1.5e-05 25.4 0.2 5.1 4 1 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EKX43381.1 - 5.2e-09 35.3 2.2 4.9e-08 32.1 0.4 2.8 2 1 1 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.7 EKX43381.1 - 1.5e-08 34.5 0.1 2.3e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EKX43381.1 - 1.6e-07 30.8 1.3 3.1e-07 29.8 1.3 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EKX43381.1 - 8.4e-07 28.5 2.8 0.0097 15.2 0.1 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EKX43381.1 - 1.9e-06 27.7 11.8 0.00016 21.4 1.3 4.4 4 1 1 5 5 5 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 EKX43381.1 - 2e-06 27.2 0.2 0.00058 19.1 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EKX43381.1 - 9e-06 25.1 0.6 0.0005 19.4 0.0 2.6 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 EKX43381.1 - 1e-05 24.8 1.0 2.6e-05 23.5 0.9 1.8 1 1 0 1 1 1 1 Glucose inhibited division protein A FMO-like PF00743.19 EKX43381.1 - 3.2e-05 22.6 0.1 0.12 10.8 0.0 3.0 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like 2-Hacid_dh_C PF02826.19 EKX43381.1 - 5.4e-05 22.6 2.6 0.81 9.0 0.0 3.6 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EKX43381.1 - 0.00011 22.1 1.1 0.006 16.5 0.1 2.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EKX43381.1 - 0.00097 18.5 0.1 0.00097 18.5 0.1 2.3 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EKX43381.1 - 0.0013 18.0 1.0 0.0054 16.0 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 EKX43381.1 - 0.0016 17.8 2.1 0.0017 17.7 0.1 2.1 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase CoA_binding PF02629.19 EKX43381.1 - 0.0022 18.6 5.3 0.5 11.1 0.0 4.2 4 0 0 4 4 3 1 CoA binding domain NAD_Gly3P_dh_N PF01210.23 EKX43381.1 - 0.0042 17.1 3.0 0.25 11.3 0.2 3.3 3 1 0 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.6 EKX43381.1 - 0.011 15.7 4.2 0.27 11.2 0.1 3.7 4 0 0 4 4 4 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EKX43381.1 - 0.047 12.7 1.5 0.1 11.6 0.1 2.1 3 0 0 3 3 3 0 Lycopene cyclase protein ThiF PF00899.21 EKX43381.1 - 0.061 12.7 0.2 0.85 8.9 0.0 2.3 2 0 0 2 2 2 0 ThiF family UDPG_MGDP_dh_N PF03721.14 EKX43381.1 - 0.085 12.4 0.1 0.4 10.2 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ldh_1_N PF00056.23 EKX43381.1 - 0.16 12.0 2.3 20 5.2 0.0 3.3 3 0 0 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EKX43381.1 - 0.45 11.0 2.7 2.5 8.6 0.1 3.1 3 0 0 3 3 3 0 Putative NAD(P)-binding Zn-ribbon_8 PF09723.10 EKX43382.1 - 0.00053 20.0 1.9 0.54 10.4 0.7 2.4 2 0 0 2 2 2 2 Zinc ribbon domain UPF1_Zn_bind PF09416.10 EKX43382.1 - 0.031 14.3 0.3 0.065 13.2 0.0 1.7 2 0 0 2 2 2 0 RNA helicase (UPF2 interacting domain) UCH PF00443.29 EKX43382.1 - 0.059 12.9 0.8 0.075 12.5 0.8 1.3 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase HypA PF01155.19 EKX43382.1 - 0.093 12.8 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA UCH_1 PF13423.6 EKX43382.1 - 0.11 12.1 4.6 6 6.3 4.6 2.1 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase HNH PF01844.23 EKX43382.1 - 0.29 11.3 2.4 3.5 7.9 2.4 2.2 1 1 1 2 2 2 0 HNH endonuclease Peptidase_C98 PF15499.6 EKX43382.1 - 7.1 6.0 6.8 97 2.3 6.8 2.1 1 1 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase EF-hand_1 PF00036.32 EKX43385.1 - 1e-15 56.0 5.7 1.2e-06 27.6 0.1 3.3 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 EKX43385.1 - 1.2e-12 46.8 5.7 0.00012 21.4 0.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EKX43385.1 - 2.2e-12 45.8 3.5 0.0002 21.0 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 EKX43385.1 - 3.1e-11 43.0 3.6 3.9e-06 26.6 0.6 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 EKX43385.1 - 2.8e-09 37.3 6.6 0.00012 22.5 2.5 2.9 2 2 0 2 2 2 2 EF-hand domain pair Caleosin PF05042.13 EKX43385.1 - 1.6e-05 24.9 2.4 0.21 11.5 0.0 3.1 2 1 1 3 3 3 3 Caleosin related protein SPARC_Ca_bdg PF10591.9 EKX43385.1 - 0.056 13.8 1.8 0.14 12.5 0.6 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region ANAPC4_WD40 PF12894.7 EKX43386.1 - 3.6e-05 24.0 0.1 0.097 13.0 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EKX43386.1 - 0.00023 21.9 1.8 0.00023 21.9 1.8 4.3 5 0 0 5 5 5 1 WD domain, G-beta repeat TMEM171 PF15471.6 EKX43386.1 - 0.053 12.5 1.1 0.082 11.9 1.1 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 TAF4 PF05236.14 EKX43387.1 - 2.3e-07 30.8 17.4 0.0026 17.6 0.4 3.2 1 1 1 2 2 2 2 Transcription initiation factor TFIID component TAF4 family Fungal_trans_2 PF11951.8 EKX43387.1 - 0.028 13.2 0.1 0.057 12.2 0.1 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF2939 PF11159.8 EKX43387.1 - 0.58 10.6 3.5 6.6 7.2 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) UCH PF00443.29 EKX43390.1 - 1.5e-21 77.1 0.0 1.5e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EKX43390.1 - 2.4e-05 24.1 0.0 3.2e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Cytochrom_B561 PF03188.16 EKX43391.1 - 0.00076 19.6 2.1 0.00076 19.6 2.1 1.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 SLATT_1 PF18181.1 EKX43391.1 - 0.012 15.5 1.2 0.015 15.2 1.2 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 DUF5423 PF17461.2 EKX43393.1 - 0.66 8.8 7.6 0.29 10.0 2.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5423) ETF PF01012.21 EKX43394.1 - 5.1e-40 137.3 6.5 7.3e-40 136.8 6.5 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 EKX43394.1 - 7.8e-35 118.8 0.7 2.5e-34 117.1 0.2 2.2 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain TPP_enzyme_M PF00205.22 EKX43394.1 - 0.046 13.4 1.5 0.16 11.7 0.3 2.5 2 2 1 3 3 3 0 Thiamine pyrophosphate enzyme, central domain EF-hand_1 PF00036.32 EKX43396.1 - 1.8e-18 64.6 15.0 1.9e-05 23.9 1.0 4.7 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 EKX43396.1 - 5.8e-15 54.0 13.4 0.0004 19.8 0.3 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EKX43396.1 - 3.7e-14 51.4 12.6 0.0015 18.3 0.1 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 EKX43396.1 - 1.6e-13 50.9 13.0 2.5e-06 27.8 2.8 3.7 2 1 2 4 4 4 4 EF-hand domain pair Ank_2 PF12796.7 EKX43396.1 - 6.9e-10 39.4 0.0 0.0011 19.6 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX43396.1 - 2.6e-09 37.4 0.2 0.042 14.4 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeats (many copies) EF-hand_8 PF13833.6 EKX43396.1 - 9.5e-07 28.6 13.0 0.087 12.7 3.1 4.8 3 1 1 4 4 4 4 EF-hand domain pair Ank PF00023.30 EKX43396.1 - 2.5e-06 27.7 0.0 0.089 13.3 0.0 3.8 3 1 1 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EKX43396.1 - 3.1e-05 24.1 2.5 0.21 11.9 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX43396.1 - 5.4e-05 23.3 0.1 8.2 7.4 0.0 5.3 5 0 0 5 5 5 1 Ankyrin repeat SPARC_Ca_bdg PF10591.9 EKX43396.1 - 0.0087 16.4 0.0 1.2 9.5 0.0 2.5 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EKX43396.1 - 0.025 14.5 3.3 2.5 8.1 0.1 3.2 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Glyco_transf_5 PF08323.11 EKX43398.1 - 1.3e-33 116.7 0.0 2.1e-23 83.3 0.0 2.2 2 0 0 2 2 2 2 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EKX43398.1 - 1.2e-13 50.9 0.0 2e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EKX43398.1 - 0.0018 18.3 0.0 0.6 10.1 0.0 3.1 3 1 0 3 3 3 2 Glycosyltransferase Family 4 DSPn PF14671.6 EKX43399.1 - 1.2e-35 123.0 0.3 1.5e-34 119.4 0.2 2.3 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EKX43399.1 - 1.3e-13 50.9 0.0 4.2e-13 49.3 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EKX43399.1 - 4.8e-05 23.5 0.0 7.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 EKX43399.1 - 0.00011 21.9 0.0 0.00026 20.7 0.0 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EKX43399.1 - 0.002 18.1 0.0 0.0031 17.5 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family cNMP_binding PF00027.29 EKX43400.1 - 7.8e-12 45.1 0.9 8.7e-11 41.8 0.9 2.0 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain LRR_6 PF13516.6 EKX43401.1 - 3.7e-11 42.1 16.3 0.00034 20.4 0.4 6.5 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.7 EKX43401.1 - 0.00012 22.4 6.9 0.003 17.9 0.1 3.7 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX43401.1 - 0.0034 17.7 1.3 2.9 8.8 0.0 4.1 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_8 PF13855.6 EKX43401.1 - 0.0046 16.7 9.1 0.21 11.3 0.4 4.2 3 2 0 3 3 3 2 Leucine rich repeat GDPD PF03009.17 EKX43403.1 - 7.2e-17 62.0 0.0 1.4e-16 61.0 0.0 1.5 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family MACPF PF01823.19 EKX43403.1 - 0.052 13.6 0.0 0.079 13.0 0.0 1.3 1 0 0 1 1 1 0 MAC/Perforin domain GDPD PF03009.17 EKX43405.1 - 8.6e-17 61.7 0.0 1.5e-16 60.9 0.0 1.5 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family MACPF PF01823.19 EKX43405.1 - 0.093 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 MAC/Perforin domain PP1c_bdg PF10488.9 EKX43409.1 - 0.002 17.7 1.4 0.0029 17.1 1.4 1.4 1 0 0 1 1 1 1 Phosphatase-1 catalytic subunit binding region DUF21 PF01595.20 EKX43410.1 - 3.8e-31 108.2 1.3 4.8e-31 107.8 1.3 1.1 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EKX43410.1 - 9.2e-06 26.0 0.1 0.011 16.2 0.0 2.8 3 0 0 3 3 3 2 CBS domain PWWP PF00855.17 EKX43411.1 - 1.1e-12 48.2 0.1 3e-12 46.8 0.1 1.7 1 0 0 1 1 1 1 PWWP domain BAH PF01426.18 EKX43411.1 - 3.9e-05 23.5 0.0 8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 BAH domain YejG PF13989.6 EKX43412.1 - 0.0084 16.5 1.8 4 7.9 0.1 2.5 2 0 0 2 2 2 2 YejG-like protein GOLD_2 PF13897.6 EKX43412.1 - 0.86 10.1 4.0 0.47 10.9 0.4 2.2 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Tom5 PF10642.9 EKX43412.1 - 7.4 6.7 12.8 1.1 9.3 0.1 3.4 4 0 0 4 4 4 0 Mitochondrial import receptor subunit or translocase Nup96 PF12110.8 EKX43413.1 - 1.8e-30 106.1 8.2 2.8e-29 102.2 8.2 2.3 1 1 0 1 1 1 1 Nuclear protein 96 ABC_membrane_2 PF06472.15 EKX43414.1 - 1.2e-29 103.5 4.4 4.9e-29 101.6 4.4 1.8 1 1 0 1 1 1 1 ABC transporter transmembrane region 2 TNFR_c6 PF00020.18 EKX43415.1 - 7.7e-39 131.8 87.3 1.7e-07 31.5 7.5 7.2 1 1 6 7 7 7 7 TNFR/NGFR cysteine-rich region Abhydrolase_1 PF00561.20 EKX43416.1 - 2.7e-14 53.5 0.0 4.2e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EKX43416.1 - 1.5e-13 51.9 0.0 2.4e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family WWE PF02825.20 EKX43416.1 - 1.3e-12 48.2 2.7 0.00012 22.6 0.0 4.0 4 0 0 4 4 4 2 WWE domain Hydrolase_4 PF12146.8 EKX43416.1 - 2.9e-10 39.8 0.0 4.7e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 EKX43416.1 - 0.00068 18.4 0.0 0.0021 16.8 0.0 1.6 1 1 0 1 1 1 1 Ndr family LIDHydrolase PF10230.9 EKX43416.1 - 0.021 14.4 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_8 PF06259.12 EKX43416.1 - 0.1 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF3530 PF12048.8 EKX43416.1 - 0.14 11.6 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Mitofilin PF09731.9 EKX43417.1 - 5.1e-10 38.9 33.4 3.1e-05 23.0 0.1 2.0 1 1 1 2 2 2 2 Mitochondrial inner membrane protein MucB_RseB PF03888.14 EKX43417.1 - 0.077 12.5 5.0 1.5 8.3 5.0 2.4 1 1 0 1 1 1 0 MucB/RseB N-terminal domain FapA PF03961.13 EKX43417.1 - 4.9 5.7 12.9 1.1 7.8 4.8 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A Ldh_1_C PF02866.18 EKX43420.1 - 2e-35 122.2 0.1 3.4e-35 121.4 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EKX43420.1 - 5.2e-32 110.9 0.1 9.5e-32 110.0 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Exostosin PF03016.15 EKX43421.1 - 1.9e-05 24.1 0.0 2.8e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Exostosin family DUF1087 PF06465.13 EKX43423.1 - 0.024 14.6 0.8 0.1 12.6 0.4 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) SBE2 PF17076.5 EKX43423.1 - 0.68 8.1 5.6 0.98 7.6 5.6 1.1 1 0 0 1 1 1 0 SBE2, cell-wall formation SWIRM-assoc_2 PF16496.5 EKX43423.1 - 1.5 7.7 9.4 2 7.2 9.4 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal RBM1CTR PF08081.11 EKX43423.1 - 2 8.5 5.9 3.8 7.7 5.9 1.5 1 0 0 1 1 1 0 RBM1CTR (NUC064) family F-box-like PF12937.7 EKX43424.1 - 1.1e-09 38.0 0.1 2.9e-09 36.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EKX43424.1 - 1.4e-07 31.2 1.3 2e-07 30.7 0.1 2.0 2 0 0 2 2 2 1 F-box domain WD40 PF00400.32 EKX43424.1 - 1.4e-06 28.9 1.2 0.0061 17.4 1.6 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat PIN7 PF18475.1 EKX43425.1 - 0.093 13.4 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 PIN domain Presenilin PF01080.17 EKX43426.1 - 0.57 8.9 0.8 0.67 8.7 0.8 1.1 1 0 0 1 1 1 0 Presenilin zf-RING_2 PF13639.6 EKX43428.1 - 0.0029 17.9 8.1 0.0029 17.9 8.1 6.6 6 1 0 6 6 6 2 Ring finger domain ZZ PF00569.17 EKX43428.1 - 0.0045 16.8 3.1 0.0045 16.8 3.1 6.3 7 2 0 7 7 7 2 Zinc finger, ZZ type Rho_GDI PF02115.17 EKX43430.1 - 2.5e-61 206.8 0.1 3e-61 206.6 0.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor WW PF00397.26 EKX43431.1 - 1.4e-08 34.7 2.3 2.6e-08 33.8 2.3 1.5 1 0 0 1 1 1 1 WW domain Sel1 PF08238.12 EKX43431.1 - 1.9e-05 25.2 12.8 0.33 11.7 0.0 4.2 4 1 0 4 4 4 3 Sel1 repeat FKBP_C PF00254.28 EKX43432.1 - 1.9e-14 53.7 0.0 2.2e-14 53.6 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Ank_5 PF13857.6 EKX43433.1 - 1.8e-15 56.8 0.3 1e-07 32.1 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX43433.1 - 4.8e-13 48.0 0.1 4.2e-06 26.7 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EKX43433.1 - 3.7e-12 46.7 0.0 9.9e-12 45.3 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX43433.1 - 4.2e-12 45.9 0.2 4.3e-06 26.9 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EKX43433.1 - 5.2e-11 42.9 0.0 6.4e-10 39.4 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF374 PF04028.13 EKX43433.1 - 0.018 14.6 0.2 1 9.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF374) Phasin PF05597.11 EKX43433.1 - 0.027 14.5 1.5 0.091 12.8 1.1 1.9 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF3606 PF12244.8 EKX43433.1 - 0.057 13.4 0.0 13 5.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) MAS20 PF02064.15 EKX43433.1 - 6.4 6.9 6.8 34 4.5 6.8 1.9 1 1 0 1 1 1 0 MAS20 protein import receptor SPRY PF00622.28 EKX43434.1 - 9.1e-17 61.3 0.0 5.7e-10 39.4 0.0 3.1 2 1 0 2 2 2 2 SPRY domain ATPase PF06745.13 EKX43434.1 - 0.05 12.9 0.0 0.2 11.0 0.1 1.8 2 0 0 2 2 2 0 KaiC OmpH PF03938.14 EKX43434.1 - 0.056 13.8 8.6 0.18 12.2 8.6 1.8 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Tup_N PF08581.10 EKX43434.1 - 0.22 11.9 4.1 3.1 8.2 1.6 2.9 2 0 0 2 2 2 0 Tup N-terminal DUF1640 PF07798.11 EKX43434.1 - 0.22 11.5 4.5 0.35 10.9 3.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) SRA1 PF07304.11 EKX43434.1 - 0.23 11.2 1.0 0.59 9.9 0.1 1.9 2 0 0 2 2 2 0 Steroid receptor RNA activator (SRA1) Apolipoprotein PF01442.18 EKX43434.1 - 1.5 8.7 12.0 3.9 7.3 9.4 2.3 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Ank_2 PF12796.7 EKX43435.1 - 5.2e-20 71.8 6.0 1.5e-11 44.7 0.6 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX43435.1 - 3.7e-16 59.3 0.2 1.6e-09 38.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX43435.1 - 1.1e-15 57.5 0.2 7.3e-08 32.5 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX43435.1 - 4.1e-12 46.0 0.8 0.00022 21.5 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EKX43435.1 - 2.6e-09 36.5 0.4 0.0017 18.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat PLAC8 PF04749.17 EKX43435.1 - 0.11 13.4 0.0 0.16 13.0 0.0 1.5 1 1 0 1 1 1 0 PLAC8 family G3P_antiterm PF04309.12 EKX43435.1 - 0.14 11.5 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator MutS_V PF00488.21 EKX43436.1 - 5.6e-30 104.8 0.2 1.4e-29 103.5 0.2 1.7 1 0 0 1 1 1 1 MutS domain V Smr PF01713.21 EKX43436.1 - 1.4e-09 38.1 0.1 1.2e-08 35.2 0.0 2.7 2 0 0 2 2 2 1 Smr domain MutS_III PF05192.18 EKX43436.1 - 3.1e-07 30.8 1.1 3.1e-07 30.8 1.1 2.8 2 1 0 2 2 1 1 MutS domain III Latarcin PF10279.9 EKX43436.1 - 0.0017 18.7 1.2 48 4.5 10.4 3.4 3 1 0 3 3 2 0 Latarcin precursor UPF0449 PF15136.6 EKX43436.1 - 0.0073 16.8 7.4 1.2 9.6 1.5 4.0 3 1 1 4 4 3 1 Uncharacterised protein family UPF0449 HAUS6_N PF14661.6 EKX43436.1 - 0.015 14.9 6.1 0.042 13.4 6.1 1.7 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus AAA_23 PF13476.6 EKX43436.1 - 0.021 15.4 13.4 2.7 8.5 7.9 3.3 4 0 0 4 4 4 0 AAA domain AAA_21 PF13304.6 EKX43436.1 - 0.027 14.3 0.6 7.2 6.3 0.2 2.7 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Exonuc_VII_L PF02601.15 EKX43436.1 - 0.059 12.9 2.3 0.09 12.3 0.8 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit AAA_14 PF13173.6 EKX43436.1 - 0.11 12.5 0.0 1.5 8.9 0.0 2.9 2 1 0 2 2 2 0 AAA domain FapA PF03961.13 EKX43436.1 - 0.23 10.0 9.0 0.39 9.3 7.9 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A Ice_nucleation PF00818.17 EKX43436.1 - 0.69 10.1 2.7 2.8 8.2 2.7 2.0 1 0 0 1 1 1 0 Ice nucleation protein repeat DUF572 PF04502.13 EKX43436.1 - 1 8.9 9.1 1.9 8.0 9.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) NTPase_1 PF03266.15 EKX43436.1 - 1.4 8.8 5.6 20 5.1 1.1 2.9 3 0 0 3 3 3 0 NTPase MAT1 PF06391.13 EKX43436.1 - 1.5 8.6 12.7 3.7 7.3 12.7 1.6 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Spc7 PF08317.11 EKX43436.1 - 1.9 7.3 16.8 1.7 7.4 14.6 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein XhlA PF10779.9 EKX43436.1 - 3 8.1 6.3 28 5.0 4.5 3.2 2 0 0 2 2 2 0 Haemolysin XhlA Snf7 PF03357.21 EKX43436.1 - 3.5 7.2 16.0 0.5 9.9 9.8 2.9 2 1 0 2 2 2 0 Snf7 Fmp27_WPPW PF10359.9 EKX43436.1 - 3.5 6.4 8.9 7.2 5.3 8.9 1.4 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF3829 PF12889.7 EKX43436.1 - 3.6 7.0 9.7 6 6.3 3.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3829) DUF4337 PF14235.6 EKX43436.1 - 3.8 7.6 11.8 1.9 8.6 8.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) LPP PF04728.13 EKX43436.1 - 9.8 6.7 7.5 47 4.5 0.1 4.2 3 1 1 4 4 4 0 Lipoprotein leucine-zipper Ank_2 PF12796.7 EKX43437.1 - 5.8e-19 68.5 0.1 5.6e-16 58.9 0.0 2.5 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 EKX43437.1 - 6e-18 64.4 0.4 0.00031 21.0 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EKX43437.1 - 4.2e-16 57.4 0.0 0.004 17.5 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EKX43437.1 - 7.5e-16 58.3 0.6 2.8e-07 31.0 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX43437.1 - 3.2e-13 49.6 0.3 7.6e-06 26.1 0.1 2.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) HEM4 PF02602.15 EKX43437.1 - 0.11 11.9 0.0 0.47 9.8 0.0 1.9 1 1 1 2 2 2 0 Uroporphyrinogen-III synthase HemD Ank_4 PF13637.6 EKX43438.1 - 2.2e-10 40.8 0.9 2.7e-07 31.0 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX43438.1 - 2.2e-10 40.5 0.1 1.1e-07 32.0 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX43438.1 - 1.9e-09 38.0 0.1 5.7e-07 30.0 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX43438.1 - 1e-08 34.7 5.2 5.7e-05 23.2 0.1 4.5 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 EKX43438.1 - 1.9e-06 28.1 7.6 3.1e-05 24.2 0.3 4.6 6 0 0 6 6 6 1 Ankyrin repeat UAA PF08449.11 EKX43439.1 - 1.6e-52 178.6 16.6 1e-37 130.0 7.7 2.0 1 1 1 2 2 2 2 UAA transporter family EamA PF00892.20 EKX43439.1 - 2e-05 24.8 16.2 0.0017 18.6 3.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family Pex24p PF06398.11 EKX43439.1 - 0.00033 19.8 0.2 0.0004 19.5 0.2 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF1761 PF08570.10 EKX43439.1 - 10 6.4 11.9 0.54 10.5 2.3 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1761) UAA PF08449.11 EKX43440.1 - 2.7e-53 181.2 13.4 1.1e-36 126.6 5.4 2.0 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.20 EKX43440.1 - 0.00097 19.3 14.9 0.012 15.8 3.3 3.1 3 0 0 3 3 3 2 EamA-like transporter family DSPn PF14671.6 EKX43441.1 - 3.3e-36 124.8 0.1 6.1e-36 124.0 0.1 1.5 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EKX43441.1 - 2.6e-11 43.5 0.0 4.2e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX43441.1 - 9.7e-05 22.0 0.0 0.00018 21.2 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX43441.1 - 0.0002 21.5 0.0 0.00032 20.8 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EKX43441.1 - 0.0036 17.3 0.0 0.005 16.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family UPF0029 PF01205.19 EKX43442.1 - 6.1e-20 71.5 0.1 1.7e-15 57.2 0.0 2.6 1 1 1 2 2 2 2 Uncharacterized protein family UPF0029 RWD PF05773.22 EKX43442.1 - 2.8e-12 47.0 0.1 8.6e-12 45.4 0.1 1.8 1 1 0 1 1 1 1 RWD domain DUF5365 PF17326.2 EKX43442.1 - 0.11 12.9 0.1 0.23 11.9 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5365) RNA_pol_Rpb6 PF01192.22 EKX43443.1 - 1.6e-14 53.6 0.0 2e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 RCC1 PF00415.18 EKX43444.1 - 2.3e-74 245.8 19.9 6.7e-15 55.4 0.1 7.0 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX43444.1 - 3.3e-46 154.2 25.6 8.6e-09 35.0 0.4 6.8 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat DUF4504 PF14953.6 EKX43445.1 - 0.14 11.5 0.2 0.2 11.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4504) WD40 PF00400.32 EKX43446.1 - 3.4e-42 141.6 28.5 3.5e-06 27.7 1.0 11.4 12 0 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX43446.1 - 9.9e-12 45.0 0.9 3.5e-06 27.2 0.0 5.6 2 2 6 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EKX43446.1 - 1.1e-07 32.0 0.2 0.26 11.1 0.0 3.7 2 1 1 4 4 4 4 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.6 EKX43446.1 - 0.0019 17.5 0.0 1.8 7.8 0.0 3.5 3 1 1 4 4 4 2 Rab3 GTPase-activating protein regulatory subunit N-terminus PD40 PF07676.12 EKX43446.1 - 0.019 14.9 1.1 45 4.1 0.1 4.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 EKX43446.1 - 0.026 13.2 0.1 1.7 7.2 0.1 2.6 3 0 0 3 3 3 0 Nucleoporin Nup120/160 TNFR_c6 PF00020.18 EKX43447.1 - 1.1e-18 67.3 105.5 2e-07 31.3 5.7 10.7 3 2 8 11 11 11 6 TNFR/NGFR cysteine-rich region F5_F8_type_C PF00754.25 EKX43447.1 - 0.0012 19.0 1.3 0.02 15.0 0.2 2.8 2 0 0 2 2 2 1 F5/8 type C domain PGM_PMM_IV PF00408.20 EKX43447.1 - 0.0012 19.0 0.2 1.3 9.2 0.0 2.3 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, C-terminal domain Ephrin_rec_like PF07699.13 EKX43447.1 - 0.016 15.0 0.4 0.016 15.0 0.4 11.3 6 3 7 13 13 13 0 Putative ephrin-receptor like DUF563 PF04577.14 EKX43448.1 - 5.6e-09 36.4 0.0 9.9e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) SAM_3 PF18016.1 EKX43448.1 - 0.0052 16.6 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Sad1_UNC PF07738.13 EKX43449.1 - 3.5e-26 91.8 0.0 2e-25 89.3 0.0 2.2 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal Peptidase_S46 PF10459.9 EKX43449.1 - 0.005 15.5 19.0 0.0066 15.2 19.0 1.1 1 0 0 1 1 1 1 Peptidase S46 STAT_alpha PF01017.20 EKX43449.1 - 0.016 15.1 9.5 0.016 15.1 9.5 2.6 2 1 1 3 3 3 0 STAT protein, all-alpha domain MFS_2 PF13347.6 EKX43449.1 - 0.16 10.5 0.0 0.23 10.0 0.0 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein Prominin PF05478.11 EKX43449.1 - 0.2 9.6 22.1 0.22 9.4 20.8 1.5 1 1 0 1 1 1 0 Prominin Condensin2nSMC PF12422.8 EKX43449.1 - 1.7 8.8 8.2 0.34 11.1 2.9 2.2 1 1 1 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit ApoO PF09769.9 EKX43449.1 - 2.8 7.9 7.6 3.7 7.5 2.4 3.1 1 1 2 3 3 3 0 Apolipoprotein O FAM184 PF15665.5 EKX43449.1 - 7.1 6.3 32.0 6.7 6.4 29.4 2.0 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B CHASE6_C PF17150.4 EKX43449.1 - 7.8 7.2 9.0 1.9 9.2 1.0 3.2 1 1 2 3 3 3 0 C-terminal domain of two-partite extracellular sensor domain LRR_6 PF13516.6 EKX43450.1 - 4.6e-11 41.8 1.6 0.066 13.3 0.1 4.4 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.7 EKX43450.1 - 1.9e-05 24.9 8.3 0.029 14.8 0.3 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX43450.1 - 0.0014 18.9 0.2 28 5.8 0.0 4.2 3 0 0 3 3 3 1 Leucine Rich Repeat WXG100 PF06013.12 EKX43450.1 - 0.014 15.7 9.5 0.018 15.3 1.1 3.0 2 1 0 2 2 2 0 Proteins of 100 residues with WXG DUF2861 PF11060.8 EKX43450.1 - 0.014 15.0 0.7 0.027 14.0 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2861) LRR_8 PF13855.6 EKX43450.1 - 0.057 13.2 8.0 0.099 12.4 0.7 3.7 2 2 0 2 2 2 0 Leucine rich repeat TTL PF03133.15 EKX43451.1 - 3.8e-49 167.4 0.0 6.8e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EKX43451.1 - 2.7e-08 33.4 0.0 0.00013 21.3 0.0 2.7 3 0 0 3 3 3 2 YheC/D like ATP-grasp EF-hand_1 PF00036.32 EKX43451.1 - 5.7e-07 28.6 0.3 0.0011 18.3 0.3 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX43451.1 - 0.00012 21.7 0.1 0.32 11.0 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain ATPgrasp_ST PF14397.6 EKX43451.1 - 0.00092 18.5 0.0 0.024 13.9 0.0 2.1 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp EF-hand_7 PF13499.6 EKX43451.1 - 0.0019 18.6 0.1 0.23 11.9 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 EKX43451.1 - 0.0025 17.6 0.3 0.019 14.8 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX43451.1 - 0.022 14.2 0.4 0.17 11.4 0.3 2.2 2 0 0 2 2 2 0 EF hand DUF525 PF04379.14 EKX43452.1 - 1.1e-22 80.1 0.0 1.7e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 ApaG domain UVR PF02151.19 EKX43452.1 - 5.3e-13 48.2 14.6 2.3e-09 36.7 2.1 2.3 2 0 0 2 2 2 2 UvrB/uvrC motif Ion_trans PF00520.31 EKX43453.1 - 2.3e-33 115.5 19.5 3.2e-33 115.0 19.5 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EKX43453.1 - 1.3e-06 27.4 18.1 1.1e-05 24.3 9.2 2.3 1 1 1 2 2 2 2 Polycystin cation channel PH PF00169.29 EKX43453.1 - 2.3e-06 28.1 0.0 6.1e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 PH domain EF-hand_6 PF13405.6 EKX43453.1 - 0.021 14.7 0.4 0.14 12.1 0.1 2.6 3 0 0 3 3 3 0 EF-hand domain KCNQ_channel PF03520.14 EKX43453.1 - 0.057 13.3 1.1 0.15 11.9 1.1 1.7 1 0 0 1 1 1 0 KCNQ voltage-gated potassium channel EF-hand_7 PF13499.6 EKX43453.1 - 0.074 13.5 0.4 0.27 11.7 0.4 2.0 1 0 0 1 1 1 0 EF-hand domain pair RNase_J_C PF17770.1 EKX43453.1 - 0.11 13.5 0.6 1 10.5 0.2 2.5 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain LSDAT_prok PF18171.1 EKX43454.1 - 2e-23 82.7 0.0 4.2e-11 42.5 0.0 2.4 2 0 0 2 2 2 2 SLOG in TRPM, prokaryote LSDAT_euk PF18139.1 EKX43454.1 - 1.3e-20 73.9 0.0 3.7e-14 52.8 0.0 2.5 2 0 0 2 2 2 2 SLOG in TRPM ALIX_LYPXL_bnd PF13949.6 EKX43455.1 - 0.0045 16.3 4.4 0.0068 15.7 4.4 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV zf_PR_Knuckle PF18445.1 EKX43455.1 - 0.028 14.2 0.7 0.063 13.1 0.7 1.6 1 0 0 1 1 1 0 PR zinc knuckle motif Nsp1_C PF05064.13 EKX43455.1 - 0.086 12.6 0.6 0.17 11.7 0.6 1.5 1 0 0 1 1 1 0 Nsp1-like C-terminal region TPR_2 PF07719.17 EKX43456.1 - 1.1e-05 25.1 1.4 0.11 12.7 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX43456.1 - 5.5e-05 23.1 1.7 0.72 10.2 0.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 EKX43456.1 - 0.00081 18.8 0.7 2.2 7.8 0.0 3.1 3 0 0 3 3 3 2 SHNi-TPR TPR_1 PF00515.28 EKX43456.1 - 0.00092 18.9 0.1 0.98 9.4 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX43456.1 - 0.049 14.0 0.0 0.15 12.5 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX43456.1 - 0.08 13.2 2.0 9.9 6.5 0.1 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat Nucleotid_trans PF03407.16 EKX43457.1 - 5.8e-11 42.8 0.0 6.4e-11 42.6 0.0 1.0 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Nucleotid_trans PF03407.16 EKX43458.1 - 7.7e-20 71.8 0.0 1.1e-19 71.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase C2 PF00168.30 EKX43461.1 - 0.00038 20.7 0.0 0.0022 18.3 0.0 2.3 1 1 0 1 1 1 1 C2 domain DOCK-C2 PF14429.6 EKX43461.1 - 0.034 14.0 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins DUF2015 PF09435.10 EKX43461.1 - 0.052 13.4 0.4 0.1 12.4 0.4 1.6 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2015) DUF5385 PF17359.2 EKX43461.1 - 0.056 13.0 0.2 0.097 12.2 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5385) DUF1670 PF07900.11 EKX43461.1 - 0.097 12.0 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1670) ArAE_2_N PF10337.9 EKX43461.1 - 0.35 9.8 2.6 0.53 9.3 2.6 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal DUF3023 PF11224.8 EKX43462.1 - 0.092 12.6 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3023) LRR_4 PF12799.7 EKX43463.1 - 1.8e-20 72.7 31.6 2e-05 24.8 0.7 4.3 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX43463.1 - 8e-17 60.8 18.0 7.4e-10 38.4 5.7 3.5 2 2 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 EKX43463.1 - 0.013 15.0 5.7 0.85 9.1 0.7 2.2 1 1 1 2 2 2 0 Leucine-rich repeat LRR_1 PF00560.33 EKX43463.1 - 0.026 15.0 16.5 3.9 8.4 0.6 6.6 5 2 0 5 5 5 0 Leucine Rich Repeat LRR_5 PF13306.6 EKX43463.1 - 0.11 12.5 0.7 1.4 8.9 0.2 2.4 1 1 1 2 2 2 0 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 EKX43463.1 - 0.26 11.4 15.6 4.9 7.5 0.2 5.3 7 0 0 7 7 7 0 Leucine Rich repeat LRR_8 PF13855.6 EKX43464.1 - 5.6e-59 195.8 130.0 9.5e-09 34.9 4.8 12.1 3 2 9 14 14 14 14 Leucine rich repeat LRR_4 PF12799.7 EKX43464.1 - 3.9e-53 176.5 106.6 1.3e-08 35.0 0.1 15.1 6 4 12 18 18 18 18 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX43464.1 - 3.9e-14 52.5 39.0 0.00034 20.2 3.5 7.6 2 2 5 8 8 8 7 Leucine-rich repeat LRR_1 PF00560.33 EKX43464.1 - 0.00012 22.1 100.9 1.5 9.7 0.7 21.3 20 5 1 21 21 21 4 Leucine Rich Repeat LRR_5 PF13306.6 EKX43464.1 - 0.00046 20.1 11.6 2.1 8.3 0.4 4.9 2 1 3 5 5 5 3 BspA type Leucine rich repeat region (6 copies) DUF3188 PF11384.8 EKX43464.1 - 0.17 11.6 0.6 27 4.6 0.0 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3188) IL4 PF00727.18 EKX43464.1 - 0.24 11.6 2.9 1.7 8.9 0.6 3.1 1 1 2 3 3 3 0 Interleukin 4 LRR_6 PF13516.6 EKX43464.1 - 2.7 8.3 79.3 0.35 11.0 0.4 15.6 18 0 0 18 18 18 0 Leucine Rich repeat Beta_helix PF13229.6 EKX43465.1 - 5.8e-14 52.2 13.2 9.3e-12 45.1 5.1 2.0 1 1 1 2 2 2 2 Right handed beta helix region SAM_2 PF07647.17 EKX43465.1 - 1e-06 28.8 0.0 1.9e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NosD PF05048.13 EKX43465.1 - 8.8e-06 25.2 1.4 2.2e-05 23.9 1.4 1.6 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) SAM_1 PF00536.30 EKX43465.1 - 0.00055 20.3 0.0 0.001 19.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF1565 PF07602.11 EKX43465.1 - 0.052 12.9 0.9 0.26 10.6 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1565) Amino_oxidase PF01593.24 EKX43466.1 - 8.9e-67 226.3 0.1 1.5e-66 225.6 0.1 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EKX43466.1 - 1.4e-09 38.1 0.0 2.5e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EKX43466.1 - 0.0012 17.7 0.3 0.73 8.5 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 EKX43466.1 - 0.011 14.8 0.6 0.029 13.4 0.6 1.9 1 1 0 1 1 1 0 FAD binding domain DSPn PF14671.6 EKX43467.1 - 3.7e-36 124.7 0.1 3.1e-34 118.4 0.0 2.3 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EKX43467.1 - 8e-13 48.4 0.0 1.6e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EKX43467.1 - 7.1e-07 29.5 0.0 1.1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 EKX43467.1 - 9.3e-06 25.4 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EKX43467.1 - 0.012 15.5 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family GMC_oxred_N PF00732.19 EKX43468.1 - 6.3e-82 275.3 1.2 3.3e-80 269.6 1.2 2.2 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EKX43468.1 - 1.6e-06 28.7 0.0 2.7e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_3 PF01494.19 EKX43468.1 - 0.00042 19.7 0.0 0.0022 17.3 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EKX43468.1 - 0.0007 18.9 0.0 0.0031 16.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EKX43468.1 - 0.0011 18.2 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EKX43468.1 - 0.0015 18.7 0.4 0.005 17.0 0.4 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EKX43468.1 - 0.009 15.1 1.7 0.014 14.5 0.2 1.9 2 0 0 2 2 2 1 FAD binding domain ApbA PF02558.16 EKX43468.1 - 0.014 15.1 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EKX43468.1 - 0.023 15.0 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain DAO PF01266.24 EKX43468.1 - 0.025 14.2 0.4 0.025 14.2 0.4 2.2 2 1 0 2 2 2 0 FAD dependent oxidoreductase ThiF PF00899.21 EKX43468.1 - 0.076 12.4 0.0 0.35 10.2 0.0 1.9 2 0 0 2 2 2 0 ThiF family HI0933_like PF03486.14 EKX43468.1 - 0.13 10.9 0.2 0.31 9.7 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein IQCJ-SCHIP1 PF15157.6 EKX43469.1 - 0.78 9.6 3.9 11 5.9 0.1 2.2 2 0 0 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif PAS_7 PF12860.7 EKX43470.1 - 0.11 12.6 0.1 0.15 12.2 0.1 1.4 1 1 0 1 1 1 0 PAS fold PAS_7 PF12860.7 EKX43471.1 - 0.15 12.3 0.0 0.27 11.4 0.0 1.4 1 1 0 1 1 1 0 PAS fold NAD_binding_8 PF13450.6 EKX43472.1 - 8.8e-14 51.5 0.2 3e-13 49.8 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EKX43472.1 - 7.8e-13 48.5 0.1 4.8e-11 42.6 0.1 2.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 EKX43472.1 - 4.2e-09 36.4 2.1 0.00031 20.5 0.0 2.7 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EKX43472.1 - 3.5e-07 29.7 0.4 0.00046 19.4 0.3 2.4 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 EKX43472.1 - 5.7e-06 25.7 0.6 0.00037 19.8 0.3 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 EKX43472.1 - 0.00022 20.6 0.3 0.00039 19.8 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EKX43472.1 - 0.00038 19.8 0.1 0.0011 18.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EKX43472.1 - 0.0006 20.3 0.1 0.03 14.9 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EKX43472.1 - 0.0028 16.4 0.0 0.67 8.6 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein GMC_oxred_N PF00732.19 EKX43472.1 - 0.003 17.0 0.0 0.0055 16.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GIDA PF01134.22 EKX43472.1 - 0.0077 15.3 0.0 0.28 10.2 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A GDI PF00996.18 EKX43472.1 - 0.033 12.7 0.2 0.062 11.8 0.0 1.4 2 0 0 2 2 2 0 GDP dissociation inhibitor FAD_oxidored PF12831.7 EKX43472.1 - 0.036 13.4 0.4 0.074 12.4 0.2 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pkinase_Tyr PF07714.17 EKX43473.1 - 4.1e-31 108.2 0.0 5.2e-24 84.9 0.0 2.5 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 EKX43473.1 - 4.8e-30 104.8 0.0 4.2e-25 88.6 0.0 2.3 1 1 0 2 2 2 2 Protein kinase domain EF-hand_6 PF13405.6 EKX43473.1 - 6e-17 60.1 9.1 0.009 15.9 0.0 6.5 6 0 0 6 6 6 5 EF-hand domain EF-hand_1 PF00036.32 EKX43473.1 - 7.5e-17 59.6 10.6 0.00047 19.5 0.2 6.3 6 0 0 6 6 6 5 EF hand EF-hand_7 PF13499.6 EKX43473.1 - 7.2e-15 55.2 5.9 0.00014 22.2 0.1 4.6 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_8 PF13833.6 EKX43473.1 - 6.5e-06 25.9 8.0 0.014 15.2 0.8 4.2 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EKX43473.1 - 0.00027 20.3 0.9 5 6.8 0.0 3.8 3 0 0 3 3 3 2 EF hand APH PF01636.23 EKX43473.1 - 0.0067 16.4 0.0 0.019 14.9 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family SelP_N PF04592.14 EKX43473.1 - 0.0088 15.5 2.2 0.015 14.8 2.2 1.4 1 0 0 1 1 1 1 Selenoprotein P, N terminal region DUF5523 PF17661.1 EKX43473.1 - 0.067 12.9 5.1 0.11 12.2 5.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) EF-hand_4 PF12763.7 EKX43473.1 - 0.28 11.2 4.7 3.5 7.6 0.1 3.9 4 1 1 5 5 5 0 Cytoskeletal-regulatory complex EF hand Cluap1 PF10234.9 EKX43474.1 - 2.8e-99 331.9 12.4 3.7e-99 331.5 12.4 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 IMS PF00817.20 EKX43474.1 - 0.052 13.6 4.7 0.29 11.1 4.7 2.1 1 1 0 1 1 1 0 impB/mucB/samB family Fez1 PF06818.15 EKX43474.1 - 6.8 7.1 22.2 1.8 9.0 16.9 2.1 1 1 2 3 3 3 0 Fez1 kleA_kleC PF17383.2 EKX43474.1 - 9.8 6.6 9.8 0.1 13.0 1.0 2.3 3 0 0 3 3 3 0 Uncharacterized KorC regulated protein A DUF4554 PF15091.6 EKX43475.1 - 1.4 7.7 5.2 3.4 6.4 5.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) CRAL_TRIO PF00650.20 EKX43479.1 - 4.3e-31 107.8 0.1 5.3e-31 107.5 0.1 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EKX43479.1 - 2.6e-05 24.3 0.1 5.9e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EKX43479.1 - 0.019 15.1 0.0 0.028 14.6 0.0 1.2 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain GST_C_2 PF13410.6 EKX43480.1 - 4.5e-10 39.4 0.0 9.7e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EKX43480.1 - 2.9e-09 37.0 0.0 5e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EKX43480.1 - 3.1e-06 27.3 0.0 7.5e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EKX43480.1 - 5.4e-05 23.4 0.2 0.0008 19.7 0.2 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 EKX43480.1 - 0.018 14.8 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Sec2p PF06428.11 EKX43480.1 - 0.2 11.6 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Ribosomal_S8e PF01201.22 EKX43481.1 - 5.3e-52 175.6 1.0 7.8e-52 175.1 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e MMR_HSR1 PF01926.23 EKX43482.1 - 8.8e-45 151.5 0.1 6.7e-23 81.0 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EKX43482.1 - 3.2e-19 69.0 0.5 1.7e-08 34.1 0.0 3.0 2 1 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 EKX43482.1 - 9.9e-17 61.1 0.2 4.9e-10 39.3 0.1 4.1 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain KH_dom-like PF14714.6 EKX43482.1 - 3.8e-15 56.0 0.0 8.1e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal AIG1 PF04548.16 EKX43482.1 - 8.5e-14 51.4 0.1 1.4e-05 24.5 0.2 2.3 2 0 0 2 2 2 2 AIG1 family Roc PF08477.13 EKX43482.1 - 1.6e-09 38.0 0.1 0.0051 17.0 0.0 4.4 5 0 0 5 5 5 2 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EKX43482.1 - 4e-09 36.8 0.0 0.11 12.6 0.0 4.4 4 0 0 4 4 4 2 Dynamin family Ras PF00071.22 EKX43482.1 - 4.4e-09 36.1 0.0 0.025 14.2 0.0 4.3 3 1 0 3 3 3 2 Ras family RsgA_GTPase PF03193.16 EKX43482.1 - 3.1e-07 30.5 0.3 0.16 11.8 0.0 3.6 3 1 0 3 3 3 2 RsgA GTPase Septin PF00735.18 EKX43482.1 - 2.6e-05 23.7 1.5 0.0085 15.4 0.4 3.6 2 2 0 2 2 2 1 Septin Arf PF00025.21 EKX43482.1 - 0.00013 21.5 0.2 0.26 10.7 0.0 3.4 4 0 0 4 4 4 1 ADP-ribosylation factor family ABC_tran PF00005.27 EKX43482.1 - 0.00024 21.7 0.0 1.7 9.1 0.0 2.7 2 1 0 3 3 2 2 ABC transporter TniB PF05621.11 EKX43482.1 - 0.00025 20.5 0.0 0.15 11.4 0.0 2.3 2 0 0 2 2 2 2 Bacterial TniB protein ATPase_2 PF01637.18 EKX43482.1 - 0.00052 20.0 0.1 0.079 12.9 0.0 2.6 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea MeaB PF03308.16 EKX43482.1 - 0.00057 18.9 0.1 0.68 8.9 0.0 3.3 3 1 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRPRB PF09439.10 EKX43482.1 - 0.0006 19.3 0.3 2.7 7.4 0.5 3.2 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EKX43482.1 - 0.00076 19.2 0.0 17 5.2 0.0 4.2 5 0 0 5 5 4 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 EKX43482.1 - 0.0017 18.0 0.0 0.27 11.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 EKX43482.1 - 0.002 18.5 0.0 0.71 10.3 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 EKX43482.1 - 0.0021 18.6 0.0 2.8 8.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain MMR_HSR1_Xtn PF16897.5 EKX43482.1 - 0.0027 17.7 0.2 0.041 13.9 0.1 2.4 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain AAA_22 PF13401.6 EKX43482.1 - 0.0028 17.9 0.0 0.92 9.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EKX43482.1 - 0.0029 17.9 0.0 2.3 8.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.15 EKX43482.1 - 0.0075 16.2 0.0 3.3 7.6 0.0 2.9 3 0 0 3 3 3 1 NTPase AAA_24 PF13479.6 EKX43482.1 - 0.0078 16.0 0.0 5 6.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.18 EKX43482.1 - 0.011 15.2 0.0 0.31 10.4 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family G-alpha PF00503.20 EKX43482.1 - 0.016 14.4 0.0 0.06 12.5 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.6 EKX43482.1 - 0.047 14.1 0.0 1.5 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain Hpr_kinase_C PF07475.12 EKX43482.1 - 0.053 13.1 0.0 1.7 8.1 0.0 2.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain NOG1 PF06858.14 EKX43482.1 - 0.074 12.8 2.1 0.65 9.8 0.1 2.9 2 1 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) ATP_bind_1 PF03029.17 EKX43482.1 - 0.15 11.9 0.0 8.8 6.0 0.0 3.3 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein EF-hand_1 PF00036.32 EKX43483.1 - 3.1e-18 63.9 7.2 1.4e-05 24.3 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EKX43483.1 - 1.7e-14 52.4 2.9 7.7e-05 22.3 0.0 4.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EKX43483.1 - 4.2e-11 41.8 5.5 0.0029 17.0 0.1 4.7 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 EKX43483.1 - 8.1e-11 42.2 10.3 9.7e-06 26.0 2.1 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 EKX43483.1 - 1.4e-06 28.0 2.4 0.099 12.5 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX43483.1 - 0.0094 16.3 3.8 12 6.3 0.1 4.0 4 0 0 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region Unstab_antitox PF09720.10 EKX43483.1 - 0.024 14.7 1.6 3.1 7.9 0.2 2.7 2 0 0 2 2 2 0 Putative addiction module component Ion_trans PF00520.31 EKX43484.1 - 7.7e-34 117.0 28.0 1.2e-33 116.4 28.0 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EKX43484.1 - 8e-06 24.8 10.9 8e-06 24.8 10.9 2.1 1 1 1 2 2 2 2 Polycystin cation channel EF-hand_1 PF00036.32 EKX43484.1 - 0.00036 19.9 0.5 0.0014 18.1 0.2 2.3 1 1 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EKX43484.1 - 0.00062 19.5 2.4 0.00081 19.1 0.6 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 EKX43484.1 - 0.0044 16.5 0.3 0.012 15.0 0.3 1.8 1 0 0 1 1 1 1 EF hand PH PF00169.29 EKX43484.1 - 0.04 14.4 0.1 0.13 12.8 0.1 1.9 1 1 0 1 1 1 0 PH domain KIP1 PF07765.12 EKX43484.1 - 0.11 12.7 0.0 0.58 10.3 0.0 2.3 1 0 0 1 1 1 0 KIP1-like protein EF-hand_7 PF13499.6 EKX43484.1 - 0.21 12.1 8.4 0.23 11.9 0.3 3.1 2 1 1 3 3 3 0 EF-hand domain pair CIMR PF00878.18 EKX43485.1 - 2.6e-09 37.3 2.6 0.00064 19.8 0.1 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.10 EKX43485.1 - 8.2e-09 35.7 5.5 2.3e-08 34.2 3.7 2.4 2 1 0 2 2 2 1 Autophagy-related protein 27 RIBIOP_C PF04950.12 EKX43487.1 - 3.8e-81 272.7 0.1 3.8e-81 272.7 0.1 2.9 3 0 0 3 3 3 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EKX43487.1 - 1.4e-30 105.2 0.0 1.4e-30 105.2 0.0 2.9 3 1 0 3 3 3 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 EKX43487.1 - 0.00045 19.8 0.0 0.064 12.8 0.0 2.8 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EKX43487.1 - 0.0012 19.2 0.9 0.03 14.7 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 EKX43487.1 - 0.0016 18.5 0.0 0.014 15.5 0.0 2.6 1 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EKX43487.1 - 0.012 15.7 0.0 0.077 13.1 0.0 2.4 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EKX43487.1 - 0.014 15.6 0.0 0.039 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EKX43487.1 - 0.028 14.8 0.0 0.095 13.1 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 EKX43487.1 - 0.11 12.7 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 EKX43487.1 - 0.25 11.4 0.0 0.25 11.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain zf-RING_2 PF13639.6 EKX43489.1 - 2e-11 44.1 5.8 2e-11 44.1 5.8 1.7 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 EKX43489.1 - 2e-09 37.0 3.8 2e-09 37.0 3.8 2.0 3 0 0 3 3 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EKX43489.1 - 2.5e-08 33.7 4.5 6e-08 32.4 4.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX43489.1 - 4.1e-08 33.1 1.9 7.5e-08 32.3 0.6 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EKX43489.1 - 1.3e-07 31.3 7.2 7.2e-07 29.0 7.2 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX43489.1 - 9.3e-07 29.0 7.7 2.2e-06 27.9 7.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EKX43489.1 - 9.9e-06 25.4 3.4 2.5e-05 24.2 3.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EKX43489.1 - 3.2e-05 23.7 3.9 8.1e-05 22.4 3.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EKX43489.1 - 3.7e-05 23.7 3.3 7e-05 22.8 3.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 EKX43489.1 - 0.025 14.7 5.3 0.083 13.0 5.3 1.9 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 EKX43489.1 - 0.034 14.3 4.0 0.034 14.3 4.0 2.2 2 1 0 2 2 1 0 FANCL C-terminal domain Baculo_RING PF05883.11 EKX43489.1 - 0.05 13.6 0.6 0.087 12.8 0.6 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Prok-RING_4 PF14447.6 EKX43489.1 - 0.074 12.9 4.0 0.21 11.4 4.0 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EKX43489.1 - 0.15 11.7 3.0 0.42 10.3 3.1 1.8 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Mut7-C PF01927.16 EKX43489.1 - 0.16 12.1 1.9 0.19 11.8 0.1 1.8 1 1 1 2 2 2 0 Mut7-C RNAse domain zf-RING_4 PF14570.6 EKX43489.1 - 0.52 10.1 7.8 0.078 12.8 3.4 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 EKX43489.1 - 1.1 9.4 10.6 1.1 9.5 4.9 2.7 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DUF3948 PF13134.6 EKX43490.1 - 0.07 12.8 1.7 0.07 12.8 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3948) Pkinase PF00069.25 EKX43491.1 - 1.7e-54 185.0 0.0 2.2e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX43491.1 - 3.6e-27 95.3 0.0 6.7e-25 87.8 0.0 2.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX43491.1 - 1.9e-06 27.4 0.1 3.4e-05 23.3 0.1 2.2 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EKX43491.1 - 6.7e-06 25.3 0.0 9.6e-06 24.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EKX43491.1 - 0.00068 19.3 0.0 0.1 12.2 0.0 2.3 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EKX43491.1 - 0.006 16.0 0.0 0.013 14.9 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX43491.1 - 0.016 15.1 0.0 0.041 13.8 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX43491.1 - 0.017 13.9 0.3 0.12 11.1 0.0 2.0 1 1 0 2 2 2 0 Fungal protein kinase Agenet PF05641.12 EKX43493.1 - 3.1e-14 53.2 1.4 6.5e-06 26.5 0.3 2.5 2 0 0 2 2 2 2 Agenet domain KH_1 PF00013.29 EKX43493.1 - 4.3e-12 45.7 0.3 4.9e-07 29.5 0.3 2.7 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 EKX43493.1 - 0.0002 21.1 0.4 0.36 10.7 0.1 2.5 2 0 0 2 2 2 2 KH domain Tudor_3 PF18115.1 EKX43493.1 - 0.012 15.4 0.1 0.039 13.8 0.0 1.9 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain DUF5348 PF17295.2 EKX43493.1 - 0.17 11.8 0.2 0.37 10.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5348) Cdc6_C PF09079.11 EKX43495.1 - 0.036 14.0 0.0 3.8 7.6 0.0 2.9 3 0 0 3 3 3 0 CDC6, C terminal winged helix domain SBF_like PF13593.6 EKX43499.1 - 5.4e-38 131.1 4.4 6.2e-38 130.9 4.4 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 EKX43499.1 - 3.2e-11 43.3 8.1 3.2e-11 43.3 8.1 1.5 1 1 1 2 2 2 1 Sodium Bile acid symporter family SelR PF01641.18 EKX43500.1 - 3.8e-41 140.0 0.0 4.4e-41 139.7 0.0 1.0 1 0 0 1 1 1 1 SelR domain FKBP_C PF00254.28 EKX43501.1 - 8.8e-21 74.0 0.0 1e-20 73.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase zf-C3HC4 PF00097.25 EKX43502.1 - 0.0072 16.2 1.8 0.015 15.2 1.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EKX43502.1 - 0.018 14.9 2.2 0.051 13.4 2.2 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sigma70_ner PF04546.13 EKX43502.1 - 0.02 14.8 3.4 0.41 10.5 1.5 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region zf-RING_5 PF14634.6 EKX43502.1 - 0.022 14.7 1.5 0.041 13.8 1.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 EKX43502.1 - 0.069 13.5 2.5 0.12 12.7 2.5 1.4 1 0 0 1 1 1 0 Ring finger domain Secretin_N_2 PF07655.13 EKX43502.1 - 1.7 9.2 6.5 0.24 11.9 0.5 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain Abhydrolase_6 PF12697.7 EKX43503.1 - 4.6e-09 37.2 0.0 0.0028 18.3 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EKX43503.1 - 2.7e-07 30.1 0.0 5.2e-05 22.6 0.1 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EKX43503.1 - 4.1e-05 23.3 0.0 0.0013 18.4 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold ATP-synt_C PF00137.21 EKX43504.1 - 0.016 15.5 0.8 0.03 14.7 0.8 1.4 1 0 0 1 1 1 0 ATP synthase subunit C UPF0016 PF01169.19 EKX43505.1 - 8.9e-49 163.7 16.3 2e-24 85.7 2.5 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 FTR1 PF03239.14 EKX43505.1 - 0.63 9.2 7.1 0.049 12.8 1.4 1.9 2 0 0 2 2 2 0 Iron permease FTR1 family TerC PF03741.16 EKX43505.1 - 8.7 6.0 13.4 0.43 10.3 6.0 2.3 2 1 0 2 2 2 0 Integral membrane protein TerC family TPR_11 PF13414.6 EKX43507.1 - 2.8e-29 100.5 19.9 0.00051 19.7 0.5 9.0 4 3 5 9 9 9 8 TPR repeat TPR_2 PF07719.17 EKX43507.1 - 1.1e-25 87.6 9.3 0.00075 19.4 0.1 10.0 9 2 2 11 11 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 EKX43507.1 - 1.7e-25 87.7 8.1 0.0022 17.8 0.0 9.0 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_17 PF13431.6 EKX43507.1 - 2.4e-19 68.2 7.8 0.03 14.7 0.0 8.7 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.6 EKX43507.1 - 2.9e-16 59.8 20.0 1.4e-06 28.8 1.8 5.9 5 1 0 6 6 6 4 Tetratricopeptide repeat DUF1736 PF08409.11 EKX43507.1 - 5.5e-16 58.3 1.0 1.2e-15 57.3 1.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_12 PF13424.6 EKX43507.1 - 4.1e-14 52.6 23.3 5.4e-06 26.6 1.7 6.1 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX43507.1 - 1.2e-11 43.9 7.7 0.05 13.8 0.1 8.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX43507.1 - 1.8e-11 43.9 17.8 0.019 15.7 0.2 8.2 3 2 6 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX43507.1 - 5.4e-10 38.6 12.8 0.13 12.3 0.1 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EKX43507.1 - 2.7e-07 31.0 16.7 0.15 12.6 0.0 5.5 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX43507.1 - 2.7e-05 23.9 34.6 0.19 11.6 1.0 7.3 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_4 PF07721.14 EKX43507.1 - 0.012 16.1 11.6 2.8 8.8 0.4 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 EKX43507.1 - 0.031 14.6 5.8 3.8 7.9 0.0 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TOM20_plant PF06552.12 EKX43507.1 - 0.13 12.0 0.6 1.5 8.6 0.1 2.7 2 0 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 SNAP PF14938.6 EKX43507.1 - 1.3 8.4 11.0 1.4 8.3 0.1 3.5 3 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_9 PF13371.6 EKX43507.1 - 6 7.1 18.4 4.4 7.5 0.4 4.9 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX43507.1 - 6.1 7.7 13.0 52 4.8 0.3 5.9 5 1 1 6 6 6 0 Tetratricopeptide repeat RWP-RK PF02042.15 EKX43508.1 - 1e-10 41.4 0.1 1.7e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX43508.1 - 0.008 15.9 0.8 0.028 14.2 0.3 2.0 1 1 1 2 2 2 1 Bacterial regulatory protein, Fis family HTH_24 PF13412.6 EKX43508.1 - 0.071 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_Tnp_ISL3 PF13542.6 EKX43508.1 - 0.12 11.9 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 EKX43508.1 - 0.15 11.9 0.8 0.58 10.0 0.0 2.2 2 0 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.6 EKX43508.1 - 0.17 12.0 2.0 0.25 11.5 0.0 2.2 2 1 0 2 2 2 0 Helix-turn-helix domain PDZ_2 PF13180.6 EKX43509.1 - 0.037 14.3 0.1 0.12 12.8 0.1 1.9 1 0 0 1 1 1 0 PDZ domain HpaB_N PF11794.8 EKX43509.1 - 0.17 11.5 1.6 0.29 10.8 0.4 2.0 2 0 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal PDZ_6 PF17820.1 EKX43509.1 - 0.52 10.2 4.2 0.28 11.0 0.8 2.4 3 0 0 3 3 3 0 PDZ domain GDA1_CD39 PF01150.17 EKX43510.1 - 2e-84 283.7 0.0 2.6e-84 283.3 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Abhydrolase_2 PF02230.16 EKX43512.1 - 0.0099 15.7 0.1 0.02 14.7 0.1 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Ebp2 PF05890.12 EKX43513.1 - 2.8e-40 138.6 9.1 3.1e-40 138.4 9.1 1.0 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Stathmin PF00836.19 EKX43513.1 - 0.001 19.0 5.3 0.0012 18.9 5.3 1.3 1 0 0 1 1 1 1 Stathmin family Hen1_L PF12623.7 EKX43514.1 - 0.023 13.7 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 RNA repair, ligase-Pnkp-associating, region of Hen1 Plasmo_rep PF12135.8 EKX43514.1 - 0.096 12.2 1.8 2.7 7.6 0.2 2.7 3 0 0 3 3 3 0 Plasmodium repeat family Ephrin_rec_like PF07699.13 EKX43515.1 - 1.9e-35 120.3 92.7 1.5e-07 31.0 12.3 8.1 2 2 5 7 7 7 7 Putative ephrin-receptor like NCD3G PF07562.14 EKX43515.1 - 1.2e-12 47.5 58.9 0.0018 18.2 8.7 7.1 2 2 3 6 6 6 6 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX43515.1 - 9.9e-10 38.7 63.4 0.0017 18.7 3.1 8.3 3 3 5 8 8 8 8 TNFR/NGFR cysteine-rich region VSP PF03302.13 EKX43515.1 - 0.22 10.3 60.9 0.21 10.4 18.1 4.0 1 1 2 3 3 3 0 Giardia variant-specific surface protein Metallophos PF00149.28 EKX43517.1 - 1.8e-10 41.7 0.0 2.1e-09 38.2 0.0 2.0 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase UCR_UQCRX_QCR9 PF05365.12 EKX43520.1 - 1.2e-14 53.9 0.1 1.5e-14 53.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Kelch_5 PF13854.6 EKX43520.1 - 0.1 12.6 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Kelch motif Cation_ATPase_C PF00689.21 EKX43521.1 - 1.2e-45 155.4 0.6 1.2e-45 155.4 0.6 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EKX43521.1 - 1.4e-28 99.7 0.1 2.3e-20 72.9 0.0 2.5 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase PF13246.6 EKX43521.1 - 8.1e-20 70.7 0.0 1.7e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EKX43521.1 - 9.1e-16 58.8 1.0 3.4e-14 53.7 1.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EKX43521.1 - 1.3e-13 50.4 0.0 2.7e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EKX43521.1 - 1.7e-05 24.7 0.4 0.03 14.1 0.3 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Arf PF00025.21 EKX43522.1 - 3.3e-80 267.6 0.1 3.8e-80 267.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EKX43522.1 - 3.3e-14 53.1 0.0 4.5e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EKX43522.1 - 5.7e-13 48.7 0.0 7.1e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EKX43522.1 - 8.5e-13 48.2 0.0 9e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EKX43522.1 - 1.1e-12 47.9 0.9 1.6e-08 34.1 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EKX43522.1 - 1.9e-10 40.5 0.0 2.5e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EKX43522.1 - 1.2e-05 25.4 0.0 1.7e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EKX43522.1 - 0.004 16.5 0.3 0.0097 15.2 0.1 1.6 2 0 0 2 2 2 1 6-phosphofructo-2-kinase Ras PF00071.22 EKX43523.1 - 1e-45 155.2 0.0 1.4e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Ras family PX PF00787.24 EKX43523.1 - 4.7e-18 65.2 0.0 9.1e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 PX domain Roc PF08477.13 EKX43523.1 - 5.2e-14 52.5 0.0 8.2e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EKX43523.1 - 3.3e-07 29.9 0.0 4.6e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EKX43523.1 - 7e-06 26.0 0.2 0.0004 20.3 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EKX43523.1 - 0.00015 21.4 0.1 0.00025 20.6 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EKX43523.1 - 0.088 12.3 0.0 0.29 10.6 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.6 EKX43523.1 - 0.12 12.7 0.0 0.41 11.0 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain adh_short PF00106.25 EKX43524.1 - 9.2e-31 106.8 0.0 1.1e-25 90.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EKX43524.1 - 6.7e-18 65.1 0.0 2.2e-16 60.1 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EKX43524.1 - 2.7e-07 30.3 0.0 4e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EKX43524.1 - 7.8e-07 29.2 0.0 1.2e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Pyr_redox_2 PF07992.14 EKX43524.1 - 0.081 12.1 0.0 0.18 11.0 0.0 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HSP70 PF00012.20 EKX43525.1 - 5e-84 282.6 2.1 1.8e-68 231.2 0.0 2.6 1 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EKX43525.1 - 2.8e-19 69.1 3.1 3.4e-13 49.1 0.0 3.2 3 0 0 3 3 3 3 MreB/Mbl protein StbA PF06406.11 EKX43525.1 - 9.5e-05 21.8 0.5 0.35 10.0 0.1 2.3 2 0 0 2 2 2 2 StbA protein FtsA PF14450.6 EKX43525.1 - 0.00041 20.7 1.3 0.062 13.7 0.1 3.2 2 2 0 2 2 2 1 Cell division protein FtsA FGGY_C PF02782.16 EKX43525.1 - 0.0028 17.4 0.3 0.0062 16.3 0.2 1.6 1 1 1 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 EKX43525.1 - 0.061 12.6 0.5 3.5 6.8 0.0 2.6 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase AAA_6 PF12774.7 EKX43527.1 - 5.5e-154 512.0 0.1 9.5e-153 507.9 0.0 2.7 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 EKX43527.1 - 1.5e-147 492.6 5.1 1.5e-147 492.6 5.1 3.2 3 1 1 4 4 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 EKX43527.1 - 2.8e-126 421.9 3.2 2.8e-126 421.9 3.2 4.0 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EKX43527.1 - 1.8e-106 355.2 0.2 3.4e-105 351.1 0.0 3.0 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EKX43527.1 - 9.7e-99 330.4 0.0 9.9e-97 323.9 0.0 3.1 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EKX43527.1 - 2.3e-87 291.8 1.3 2.3e-87 291.8 1.3 2.6 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 EKX43527.1 - 3.2e-70 235.3 0.6 7.4e-68 227.6 0.0 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EKX43527.1 - 1e-54 184.8 0.1 1.4e-53 181.0 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 EKX43527.1 - 4.1e-50 170.8 14.8 1.1e-49 169.3 14.8 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EKX43527.1 - 1.4e-42 144.6 0.2 1.6e-40 137.9 0.0 3.3 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EKX43527.1 - 8.5e-32 109.9 0.4 6.2e-31 107.2 0.1 2.7 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EKX43527.1 - 1.5e-22 80.0 0.0 4e-08 33.3 0.0 5.7 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 EKX43527.1 - 1e-17 64.2 2.4 3.3e-17 62.5 0.0 3.1 3 0 0 3 3 3 1 AAA+ lid domain AAA PF00004.29 EKX43527.1 - 3.2e-06 27.6 0.2 0.049 14.1 0.0 3.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX43527.1 - 6.5e-05 23.4 1.3 0.21 11.9 0.0 4.8 4 0 0 4 4 3 1 AAA ATPase domain AAA_29 PF13555.6 EKX43527.1 - 0.00056 19.6 1.0 1.7 8.5 0.0 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EKX43527.1 - 0.00092 19.5 0.5 2.7 8.3 0.0 4.6 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 EKX43527.1 - 0.0039 17.7 0.0 2.2 8.9 0.0 4.1 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 EKX43527.1 - 0.022 14.9 0.2 13 6.0 0.0 3.5 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 EKX43527.1 - 0.035 14.3 0.0 2.4 8.4 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 EKX43527.1 - 0.044 14.2 0.5 24 5.4 0.0 3.4 4 0 0 4 4 2 0 RNA helicase Sigma54_activat PF00158.26 EKX43527.1 - 0.047 13.4 0.1 2.2 8.0 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_30 PF13604.6 EKX43527.1 - 0.059 13.1 2.5 3.7 7.2 0.1 3.3 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 EKX43527.1 - 0.072 12.8 0.2 17 5.1 0.0 3.1 2 0 0 2 2 2 0 AAA domain OTU PF02338.19 EKX43528.1 - 1.6e-25 90.1 1.2 1.7e-25 90.0 0.3 1.4 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EKX43528.1 - 2.5e-07 30.4 0.0 8.3e-06 25.4 0.0 2.0 1 1 1 2 2 2 2 Peptidase C65 Otubain RlaP PF10127.9 EKX43528.1 - 0.07 12.7 0.1 0.07 12.7 0.1 1.7 2 0 0 2 2 2 0 RNA repair pathway DNA polymerase beta family DUF4629 PF15442.6 EKX43529.1 - 8.5 6.6 10.6 0.58 10.4 4.1 2.3 2 2 0 2 2 2 0 Domain of unknown function (DUF4629) START PF01852.19 EKX43532.1 - 1.4e-07 31.1 0.5 5.2e-07 29.3 0.1 1.8 1 1 1 2 2 2 1 START domain Polyketide_cyc PF03364.20 EKX43532.1 - 0.00067 19.9 0.1 0.0013 18.9 0.1 1.5 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 EKX43532.1 - 0.036 14.4 0.1 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport DEAD PF00270.29 EKX43533.1 - 6e-38 130.3 0.4 9.1e-38 129.8 0.4 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX43533.1 - 3.4e-30 104.6 0.0 9.6e-30 103.2 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX43533.1 - 0.0044 17.0 0.0 0.0061 16.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EKX43533.1 - 0.029 14.7 0.6 0.22 11.9 0.7 2.3 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EKX43533.1 - 0.034 13.9 0.8 0.079 12.7 0.8 1.6 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 EKX43533.1 - 0.074 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 EKX43533.1 - 0.11 12.8 0.1 0.41 10.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.6 EKX43533.1 - 0.13 11.6 0.1 0.4 10.0 0.1 1.8 1 1 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit PhoH PF02562.16 EKX43533.1 - 0.14 11.6 1.5 0.18 11.2 0.2 1.8 2 0 0 2 2 2 0 PhoH-like protein MORN PF02493.20 EKX43534.1 - 1.3e-26 90.9 28.0 2.5e-08 33.3 0.7 5.7 6 0 0 6 6 6 4 MORN repeat Ndc1_Nup PF09531.10 EKX43535.1 - 0.14 10.8 0.1 0.17 10.5 0.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PRP38 PF03371.15 EKX43536.1 - 1.1e-41 142.6 0.0 1.6e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 PRP38 family SMN PF06003.12 EKX43536.1 - 0.00026 20.3 1.3 0.00026 20.3 1.3 2.8 1 1 2 3 3 3 1 Survival motor neuron protein (SMN) DUF1024 PF06260.12 EKX43536.1 - 0.029 14.6 0.1 0.066 13.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1024) TUDOR PF00567.24 EKX43536.1 - 0.039 14.0 0.0 0.086 12.9 0.0 1.5 1 0 0 1 1 1 0 Tudor domain CDC45 PF02724.14 EKX43536.1 - 0.43 8.8 24.9 0.68 8.1 24.9 1.3 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 EKX43536.1 - 2.8 6.7 14.0 4.5 6.0 14.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain zf_C2H2_ZHX PF18387.1 EKX43537.1 - 0.045 13.4 0.2 9.6 5.9 0.0 2.3 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Trypan_PARP PF05887.11 EKX43537.1 - 0.39 10.7 8.4 0.61 10.1 8.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FRQ PF09421.10 EKX43538.1 - 0.001 17.3 1.0 0.0012 17.0 1.0 1.1 1 0 0 1 1 1 1 Frequency clock protein PK PF00224.21 EKX43540.1 - 1.2e-106 356.5 0.0 1.6e-106 356.1 0.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EKX43540.1 - 2.3e-30 105.2 0.0 6.6e-30 103.8 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain IMPDH PF00478.25 EKX43540.1 - 0.0049 15.9 0.0 0.021 13.8 0.0 1.8 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain UreE_N PF02814.15 EKX43540.1 - 0.021 14.4 0.8 0.061 12.9 0.3 2.1 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain Integrase_Zn PF02022.19 EKX43542.1 - 0.12 12.3 0.6 0.52 10.3 0.0 2.2 2 0 0 2 2 2 0 Integrase Zinc binding domain Zn_clus PF00172.18 EKX43543.1 - 0.01 16.0 10.8 0.01 16.0 10.8 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SGL PF08450.12 EKX43545.1 - 0.036 13.6 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region WD40 PF00400.32 EKX43545.1 - 0.88 10.5 5.6 5.9 7.9 0.1 4.6 4 1 0 4 4 4 0 WD domain, G-beta repeat Zn_clus PF00172.18 EKX43546.1 - 2.8e-07 30.6 12.0 2.8e-07 30.6 12.0 3.2 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.29 EKX43546.1 - 3.1e-07 30.2 3.9 3.1e-07 30.2 3.9 3.6 4 1 1 5 5 5 1 PHD-finger zf-HC5HC2H PF13771.6 EKX43546.1 - 0.014 15.6 0.1 0.014 15.6 0.1 3.6 4 0 0 4 4 4 0 PHD-like zinc-binding domain zf-BED PF02892.15 EKX43546.1 - 0.14 12.2 3.5 0.26 11.3 1.3 2.4 2 0 0 2 2 2 0 BED zinc finger N6_Mtase PF02384.16 EKX43547.1 - 3e-08 33.3 0.0 4.6e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase UPF0020 PF01170.18 EKX43547.1 - 2e-07 30.9 0.2 1.3e-06 28.2 0.2 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 EKX43547.1 - 0.0007 19.3 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 N6_N4_Mtase PF01555.18 EKX43547.1 - 0.017 14.8 0.0 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 DNA methylase PDZ_2 PF13180.6 EKX43548.1 - 1.3e-06 28.6 0.0 7.2e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX43548.1 - 4.6e-06 26.9 0.0 9e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX43548.1 - 0.015 15.1 0.2 0.054 13.3 0.1 1.9 2 0 0 2 2 2 0 PDZ domain Dendrin PF15498.6 EKX43549.1 - 0.13 10.9 0.7 0.19 10.5 0.7 1.1 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin IstB_IS21 PF01695.17 EKX43550.1 - 0.0025 17.6 0.0 0.0058 16.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_11 PF13086.6 EKX43550.1 - 0.0028 17.5 23.5 0.0054 16.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EKX43550.1 - 0.02 15.1 6.1 0.26 11.6 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EKX43550.1 - 0.031 14.0 0.4 0.085 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EKX43550.1 - 0.068 12.7 1.4 0.096 12.3 0.0 2.0 2 2 0 2 2 2 0 AAA domain ATPase PF06745.13 EKX43550.1 - 0.14 11.5 0.0 0.14 11.5 0.0 2.5 2 1 1 3 3 3 0 KaiC AAA_7 PF12775.7 EKX43550.1 - 0.14 11.6 0.0 0.46 10.0 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 EKX43550.1 - 0.22 12.0 1.1 0.45 10.9 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EKX43550.1 - 0.23 11.8 0.1 0.23 11.8 0.1 1.7 2 1 0 2 2 2 0 AAA domain Spc7 PF08317.11 EKX43550.1 - 0.54 9.1 25.2 0.08 11.8 12.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 EKX43550.1 - 0.62 7.9 12.7 0.78 7.6 12.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4140 PF13600.6 EKX43550.1 - 2.5 8.6 17.0 4.3 7.8 0.8 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) KfrA_N PF11740.8 EKX43550.1 - 4.2 8.1 14.9 13 6.5 6.3 2.5 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term HTH_Tnp_Tc5 PF03221.16 EKX43551.1 - 3.6e-08 33.3 0.0 7.2e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 EKX43551.1 - 4.8e-06 26.1 0.3 9.8e-06 25.1 0.3 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_3 PF01381.22 EKX43551.1 - 0.0092 16.0 0.7 0.023 14.7 0.2 1.9 2 0 0 2 2 2 1 Helix-turn-helix HTH_38 PF13936.6 EKX43551.1 - 0.013 15.2 0.3 0.037 13.8 0.3 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_37 PF13744.6 EKX43551.1 - 0.049 13.6 0.3 0.11 12.5 0.3 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_19 PF12844.7 EKX43551.1 - 0.068 13.2 0.2 1.1 9.3 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Crp_2 PF13545.6 EKX43551.1 - 0.069 13.1 0.5 0.7 9.9 0.0 2.6 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain DUF134 PF02001.16 EKX43551.1 - 0.15 12.7 0.2 0.41 11.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF134 NAC PF01849.18 EKX43552.1 - 1.1e-22 79.7 0.1 2e-22 78.9 0.1 1.4 1 0 0 1 1 1 1 NAC domain Ribosomal_60s PF00428.19 EKX43554.1 - 0.037 14.6 9.4 0.037 14.6 9.4 3.9 2 1 1 3 3 3 0 60s Acidic ribosomal protein DUF1204 PF06721.11 EKX43555.1 - 0.00072 19.1 0.1 0.00097 18.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1204) Zn_clus PF00172.18 EKX43556.1 - 1.4e-08 34.7 9.6 1.9e-08 34.3 9.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med27 PF11571.8 EKX43556.1 - 0.22 11.9 4.4 0.44 10.9 4.4 1.6 1 1 0 1 1 1 0 Mediator complex subunit 27 NUDIX PF00293.28 EKX43557.1 - 1.5e-07 31.5 0.0 3.5e-07 30.3 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain AMP-binding PF00501.28 EKX43559.1 - 1.2e-61 208.6 0.0 1.6e-61 208.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme DUF5370 PF17340.2 EKX43559.1 - 0.18 11.7 0.0 0.51 10.3 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5370) FF PF01846.19 EKX43560.1 - 3.3e-48 161.6 17.9 1e-12 48.0 0.4 5.5 5 0 0 5 5 5 5 FF domain WW PF00397.26 EKX43560.1 - 4.8e-19 68.1 17.3 1.1e-09 38.2 2.7 2.7 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 EKX43560.1 - 0.0037 17.9 0.4 0.0037 17.9 0.4 5.1 5 1 1 6 6 6 1 p190-A and -B Rho GAPs FF domain Pox_A11 PF05061.13 EKX43560.1 - 0.88 8.8 5.4 0.095 12.0 1.0 1.6 2 0 0 2 2 2 0 Poxvirus A11 Protein TetR_C_24 PF17932.1 EKX43560.1 - 2 8.7 11.1 0.1 12.9 1.1 3.1 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain NUDIX PF00293.28 EKX43561.1 - 2.1e-07 31.0 0.0 4.7e-07 29.9 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain Glyco_transf_41 PF13844.6 EKX43562.1 - 4.3e-38 131.0 0.0 1.9e-27 95.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_16 PF13432.6 EKX43562.1 - 4.3e-06 27.3 0.0 1.5e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX43562.1 - 7.9e-06 26.1 0.3 0.0062 16.8 0.1 3.3 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX43562.1 - 3.9e-05 23.4 0.2 0.49 10.6 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX43562.1 - 0.00014 21.8 0.0 2 8.8 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX43562.1 - 0.0019 17.9 0.0 2.6 8.0 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat PKK PF12474.8 EKX43562.1 - 0.008 16.3 2.7 0.008 16.3 2.7 2.1 2 0 0 2 2 2 1 Polo kinase kinase TPR_14 PF13428.6 EKX43562.1 - 0.026 15.3 0.4 6.2 7.9 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX43562.1 - 0.029 14.9 0.0 0.057 13.9 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX43562.1 - 0.038 13.9 3.8 1.7 8.6 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EKX43562.1 - 0.053 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 TPR repeat RAP PF08373.10 EKX43565.1 - 7.4e-13 48.4 0.0 1.6e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 RAP domain Agenet PF05641.12 EKX43565.1 - 0.01 16.3 0.3 0.032 14.7 0.3 1.8 1 0 0 1 1 1 0 Agenet domain DAO_C PF16901.5 EKX43565.1 - 0.021 14.7 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase PAP1 PF08601.10 EKX43565.1 - 0.18 11.5 10.9 0.32 10.7 10.9 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 SR-25 PF10500.9 EKX43565.1 - 0.46 10.1 13.8 1.1 8.9 13.8 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3558 PF12079.8 EKX43565.1 - 3 7.8 7.0 8 6.4 7.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) Complex1_LYR PF05347.15 EKX43566.1 - 0.0044 17.0 2.8 0.05 13.7 2.8 2.2 1 1 0 1 1 1 1 Complex 1 protein (LYR family) PLU-1 PF08429.11 EKX43566.1 - 0.037 13.2 0.4 0.049 12.8 0.4 1.1 1 0 0 1 1 1 0 PLU-1-like protein Complex1_LYR_2 PF13233.6 EKX43566.1 - 0.1 13.4 3.1 0.16 12.7 3.1 1.4 1 1 0 1 1 1 0 Complex1_LYR-like Adeno_E4 PF05385.11 EKX43566.1 - 4.5 7.4 6.3 0.31 11.1 0.6 1.8 1 1 0 2 2 2 0 Mastadenovirus early E4 13 kDa protein zf-RING_2 PF13639.6 EKX43567.1 - 2.2e-11 43.9 10.6 3.4e-11 43.3 10.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EKX43567.1 - 1.7e-08 34.1 6.7 1.7e-08 34.1 6.7 1.6 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EKX43567.1 - 1.8e-07 30.9 10.0 2.9e-07 30.2 10.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX43567.1 - 2.5e-06 27.2 10.3 4.1e-06 26.6 10.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX43567.1 - 8.3e-06 26.0 7.6 1.7e-05 25.0 7.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EKX43567.1 - 3.9e-05 23.4 7.6 6.4e-05 22.7 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX43567.1 - 0.00034 20.5 9.0 0.00053 19.9 9.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EKX43567.1 - 0.00043 20.2 3.9 0.00043 20.2 3.9 1.6 1 1 0 1 1 1 1 RING-type zinc-finger RNF220 PF15926.5 EKX43567.1 - 0.0089 15.7 0.3 0.022 14.4 0.3 1.7 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 zf-ANAPC11 PF12861.7 EKX43567.1 - 0.023 14.8 2.1 0.045 13.8 2.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_16 PF17034.5 EKX43567.1 - 0.03 14.5 2.4 0.072 13.3 2.4 1.7 1 0 0 1 1 1 0 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 EKX43567.1 - 0.1 12.2 6.9 0.18 11.4 6.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type YscO PF07321.12 EKX43567.1 - 0.12 12.3 2.1 0.29 11.1 2.1 1.6 1 0 0 1 1 1 0 Type III secretion protein YscO Prok-RING_4 PF14447.6 EKX43567.1 - 0.15 12.0 8.5 0.25 11.2 8.5 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Phage_HK97_TLTM PF06120.11 EKX43567.1 - 0.15 11.2 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 Tail length tape measure protein CTU2 PF10288.9 EKX43567.1 - 0.51 10.6 7.3 9.1 6.6 5.8 2.6 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 RINGv PF12906.7 EKX43567.1 - 3.6 7.8 7.8 8.6 6.6 7.8 1.7 1 1 0 1 1 1 0 RING-variant domain EF-hand_4 PF12763.7 EKX43570.1 - 3.4e-12 46.2 0.0 1.5e-11 44.2 0.0 2.0 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand UBA PF00627.31 EKX43570.1 - 0.00018 21.4 0.0 0.00044 20.1 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain DUF5102 PF17104.5 EKX43570.1 - 0.00069 19.7 0.2 0.00069 19.7 0.2 6.0 5 1 1 6 6 6 2 Domain of unknown function (DUF5102) UBA_4 PF14555.6 EKX43570.1 - 0.0037 17.0 0.6 0.044 13.6 0.2 2.6 2 0 0 2 2 2 1 UBA-like domain EF-hand_7 PF13499.6 EKX43570.1 - 0.072 13.5 0.0 0.25 11.8 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair DUF5401 PF17380.2 EKX43571.1 - 5.8 4.9 9.4 6.5 4.7 9.4 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) AP2 PF00847.20 EKX43573.1 - 2.3e-08 34.1 4.7 1.4e-05 25.2 1.2 2.8 2 0 0 2 2 2 2 AP2 domain Agenet PF05641.12 EKX43573.1 - 8.8e-07 29.3 0.0 0.8 10.2 0.0 4.9 4 0 0 4 4 4 2 Agenet domain DUF4537 PF15057.6 EKX43573.1 - 0.00035 20.6 0.1 7.7 6.6 0.0 4.3 4 0 0 4 4 4 1 Domain of unknown function (DUF4537) Tudor_3 PF18115.1 EKX43573.1 - 0.0007 19.4 0.1 0.0069 16.2 0.0 2.8 2 0 0 2 2 2 1 DNA repair protein Crb2 Tudor domain LBR_tudor PF09465.10 EKX43573.1 - 0.011 15.6 0.1 5.7 6.8 0.0 3.3 3 0 0 3 3 3 0 Lamin-B receptor of TUDOR domain TUDOR_5 PF18359.1 EKX43573.1 - 0.052 13.3 9.7 5.1 6.9 0.0 5.2 4 2 1 5 5 5 0 Histone methyltransferase Tudor domain 1 Tudor_2 PF18104.1 EKX43573.1 - 3.1 7.6 12.6 1.7 8.4 0.0 4.5 5 0 0 5 5 5 0 Jumonji domain-containing protein 2A Tudor domain YGGT PF02325.17 EKX43574.1 - 0.0056 17.1 1.3 0.008 16.6 1.3 1.2 1 0 0 1 1 1 1 YGGT family KRTDAP PF15200.6 EKX43574.1 - 0.085 12.6 0.3 0.43 10.4 0.0 2.1 1 1 1 2 2 2 0 Keratinocyte differentiation-associated DUF641 PF04859.12 EKX43575.1 - 0.0061 16.9 7.2 0.0061 16.9 7.2 5.8 1 1 4 5 5 5 2 Plant protein of unknown function (DUF641) FAM110_N PF14161.6 EKX43575.1 - 0.48 10.7 6.2 0.19 12.0 0.3 2.8 3 0 0 3 3 3 0 Centrosome-associated N terminus Baculo_PEP_C PF04513.12 EKX43575.1 - 0.75 9.8 4.6 4 7.5 0.3 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 EKX43575.1 - 6.3 7.1 10.6 11 6.3 0.3 3.6 1 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) TPR_11 PF13414.6 EKX43577.1 - 9.9e-09 34.7 0.4 8e-08 31.8 0.0 2.3 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 EKX43577.1 - 4e-06 26.5 0.9 0.00039 20.3 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX43577.1 - 0.00058 19.6 4.0 0.026 14.3 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX43577.1 - 0.014 16.2 0.2 0.084 13.7 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EKX43577.1 - 0.022 15.1 0.1 0.43 11.1 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EKX43577.1 - 0.031 14.9 0.2 0.089 13.5 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX43577.1 - 0.065 13.5 0.3 3.4 8.1 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 EKX43577.1 - 0.081 13.1 0.1 0.22 11.7 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Med27 PF11571.8 EKX43577.1 - 0.17 12.3 0.4 7.8 6.9 0.0 2.9 3 0 0 3 3 3 0 Mediator complex subunit 27 NUDIX PF00293.28 EKX43578.1 - 2.4e-09 37.3 0.0 3.8e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 EKX43578.1 - 1.6e-07 31.3 0.0 0.0032 17.4 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4743) Glyco_transf_8 PF01501.20 EKX43579.1 - 2.1e-10 40.6 0.6 4.5e-10 39.5 0.6 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EKX43579.1 - 0.069 12.5 0.1 0.097 12.0 0.1 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative E1-E2_ATPase PF00122.20 EKX43580.1 - 1.8e-12 47.1 0.7 5.6e-12 45.6 0.9 1.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 EKX43580.1 - 0.00053 19.6 0.0 0.00091 18.9 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus PDZ PF00595.24 EKX43582.1 - 2.2e-11 43.9 0.0 8.3e-11 42.1 0.0 2.0 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX43582.1 - 1.4e-08 34.5 0.1 3.9e-08 33.0 0.1 1.8 1 0 0 1 1 1 1 PDZ domain Lebercilin PF15619.6 EKX43582.1 - 2.7e-05 23.9 26.9 2.7e-05 23.9 26.9 8.0 4 3 4 8 8 8 1 Ciliary protein causing Leber congenital amaurosis disease DUF812 PF05667.11 EKX43582.1 - 0.00022 20.3 37.2 0.00022 20.3 37.2 4.5 1 1 2 4 4 4 1 Protein of unknown function (DUF812) BST2 PF16716.5 EKX43582.1 - 0.008 16.7 3.8 0.008 16.7 3.8 11.7 8 5 5 13 13 13 1 Bone marrow stromal antigen 2 PDZ_2 PF13180.6 EKX43582.1 - 0.13 12.6 0.0 0.76 10.1 0.0 2.4 2 0 0 2 2 2 0 PDZ domain DUF3138 PF11336.8 EKX43582.1 - 0.57 8.7 2.4 7.3 5.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) CN_hydrolase PF00795.22 EKX43585.1 - 2.4e-43 148.4 0.0 3.2e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MatE PF01554.18 EKX43586.1 - 1e-27 96.8 32.7 3.1e-20 72.5 13.0 2.6 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 EKX43586.1 - 0.00011 22.3 7.1 0.00011 22.3 7.1 5.0 3 3 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Glyco_hydro_106 PF17132.4 EKX43586.1 - 0.32 9.2 0.0 0.42 8.8 0.0 1.0 1 0 0 1 1 1 0 alpha-L-rhamnosidase TRM13 PF05206.14 EKX43587.1 - 9.7e-53 179.4 1.0 2.1e-52 178.2 1.0 1.5 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.8 EKX43587.1 - 5e-06 26.2 2.5 5e-06 26.2 2.5 2.7 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein zf-C3Hc3H PF13891.6 EKX43587.1 - 0.043 14.2 4.8 2.6 8.5 0.3 3.0 2 0 0 2 2 2 0 Potential DNA-binding domain Maf PF02545.14 EKX43588.1 - 1.4e-29 103.1 0.0 5.9e-29 101.0 0.0 1.9 2 0 0 2 2 2 1 Maf-like protein Collagen PF01391.18 EKX43588.1 - 0.00011 21.9 13.5 0.016 15.0 13.5 2.2 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Pkinase PF00069.25 EKX43590.1 - 1.5e-38 132.7 0.0 7.8e-37 127.1 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX43590.1 - 2.5e-13 49.9 0.1 1.5e-12 47.3 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX43590.1 - 0.079 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 EKX43590.1 - 0.12 12.0 0.0 0.47 10.0 0.0 1.9 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 EKX43590.1 - 0.16 11.8 0.1 0.49 10.3 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family SAM_4 PF18017.1 EKX43592.1 - 0.059 13.3 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Glyco_transf_49 PF13896.6 EKX43596.1 - 3.9e-21 75.8 3.2 1.3e-11 44.4 0.5 3.0 2 1 1 3 3 3 3 Glycosyl-transferase for dystroglycan HSP20 PF00011.21 EKX43598.1 - 3.8e-12 46.3 0.1 6.9e-12 45.4 0.1 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EKX43598.1 - 6e-05 22.5 0.0 0.00015 21.3 0.0 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA SKA1 PF07160.12 EKX43599.1 - 0.0023 17.8 0.3 0.0023 17.8 0.3 3.5 2 1 0 3 3 3 1 Spindle and kinetochore-associated protein 1 DUF3005 PF11448.8 EKX43599.1 - 0.005 16.9 0.0 0.019 15.0 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3005) adh_short PF00106.25 EKX43602.1 - 4.2e-19 68.8 0.0 1.3e-18 67.2 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EKX43602.1 - 2.7e-10 40.2 0.0 3.6e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX43602.1 - 2.1e-05 24.5 0.0 2.6e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EKX43602.1 - 0.047 13.2 0.0 0.067 12.6 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ribosomal_S27e PF01667.17 EKX43602.1 - 0.085 12.6 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S27 Malic_M PF03949.15 EKX43603.1 - 5.3e-77 258.6 0.2 2.8e-75 252.9 0.2 2.6 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EKX43603.1 - 8.2e-60 201.7 0.0 1.4e-59 201.0 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain YkyA PF10368.9 EKX43604.1 - 0.023 14.4 12.6 0.046 13.4 12.6 1.5 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein IstB_IS21 PF01695.17 EKX43604.1 - 0.024 14.4 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 EKX43604.1 - 0.034 13.9 0.1 0.034 13.9 0.1 3.0 2 1 0 3 3 3 0 AAA domain DUF2828 PF11443.8 EKX43604.1 - 0.037 12.1 0.4 0.059 11.5 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Dendrin PF15498.6 EKX43604.1 - 0.044 12.5 1.2 0.067 11.9 1.2 1.2 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin AAA_22 PF13401.6 EKX43604.1 - 0.049 13.9 3.6 0.7 10.2 0.1 3.0 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 EKX43604.1 - 0.058 13.1 0.1 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EKX43604.1 - 0.08 12.7 1.6 0.34 10.6 0.3 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EKX43604.1 - 0.13 11.9 0.0 0.39 10.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EKX43604.1 - 0.19 12.1 0.1 0.48 10.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain NeuB PF03102.14 EKX43604.1 - 0.19 11.2 0.2 0.35 10.3 0.2 1.3 1 0 0 1 1 1 0 NeuB family ATPase PF06745.13 EKX43604.1 - 0.19 11.1 1.4 0.3 10.4 0.0 2.0 2 0 0 2 2 2 0 KaiC Mis12 PF05859.12 EKX43604.1 - 0.29 11.2 4.5 9.2 6.3 0.0 3.0 3 0 0 3 3 3 0 Mis12 protein RRM_3 PF08777.11 EKX43604.1 - 0.31 11.1 5.9 2.5 8.2 5.4 2.5 2 0 0 2 2 2 0 RNA binding motif Med9 PF07544.13 EKX43604.1 - 0.82 9.8 8.2 2.5 8.3 8.2 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DegS PF05384.11 EKX43604.1 - 0.93 9.0 12.7 2.1 7.8 12.7 1.6 1 0 0 1 1 1 0 Sensor protein DegS V_ATPase_I PF01496.19 EKX43604.1 - 6.3 4.6 6.2 11 3.8 6.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.20 EKX43604.1 - 7.7 6.5 18.6 3.8 7.5 8.8 2.9 3 0 0 3 3 2 0 Prefoldin subunit Cons_hypoth698 PF03601.14 EKX43605.1 - 3e-57 193.8 15.0 3.9e-57 193.5 15.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 698 FKBP_C PF00254.28 EKX43607.1 - 8.3e-16 58.1 0.2 3.4e-15 56.1 0.2 1.9 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Prominin PF05478.11 EKX43608.1 - 5.4e-06 24.7 2.8 7.9e-06 24.1 2.8 1.2 1 0 0 1 1 1 1 Prominin PH PF00169.29 EKX43608.1 - 0.00019 21.9 0.0 0.00039 20.9 0.0 1.5 1 0 0 1 1 1 1 PH domain Apolipoprotein PF01442.18 EKX43608.1 - 0.16 11.9 14.3 3.3 7.6 14.2 2.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 EKX43608.1 - 0.69 10.0 3.6 4.2 7.4 0.6 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SKA1 PF07160.12 EKX43608.1 - 1.1 9.0 6.9 4.6 7.0 0.8 2.4 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF4407 PF14362.6 EKX43608.1 - 1.4 8.2 12.0 0.11 11.8 4.3 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) Muted PF14942.6 EKX43608.1 - 1.5 9.2 6.3 7.5 6.9 1.2 2.5 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein PspB PF06667.12 EKX43608.1 - 1.8 8.7 5.7 1.2 9.2 0.3 3.1 2 2 2 4 4 4 0 Phage shock protein B DUF948 PF06103.11 EKX43608.1 - 2.3 8.6 4.6 1.2 9.5 0.1 2.8 4 0 0 4 4 3 0 Bacterial protein of unknown function (DUF948) Phasin PF05597.11 EKX43608.1 - 2.3 8.2 7.3 11 6.0 0.1 2.8 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4510 PF14971.6 EKX43608.1 - 3 8.2 12.5 0.21 11.9 5.5 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4510) IF4E PF01652.18 EKX43609.1 - 5.3e-44 149.8 0.0 6.4e-44 149.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF2387 PF09526.10 EKX43609.1 - 0.041 14.0 0.0 0.07 13.3 0.0 1.4 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) NHL PF01436.21 EKX43611.1 - 1.5e-07 31.0 9.1 0.61 10.2 0.1 6.2 6 0 0 6 6 6 4 NHL repeat SGL PF08450.12 EKX43611.1 - 0.016 14.8 0.0 3.9 7.0 0.0 3.3 1 1 2 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region SdiA-regulated PF06977.11 EKX43611.1 - 0.071 12.3 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 SdiA-regulated RWP-RK PF02042.15 EKX43612.1 - 3.7e-15 55.6 0.0 6.2e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain PTPRCAP PF15713.5 EKX43612.1 - 0.00039 20.7 3.0 0.00052 20.3 3.0 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated Myc_N PF01056.18 EKX43612.1 - 0.0019 18.2 0.9 0.0022 18.0 0.9 1.1 1 0 0 1 1 1 1 Myc amino-terminal region NOA36 PF06524.12 EKX43612.1 - 0.019 14.3 5.3 0.031 13.6 5.1 1.4 2 0 0 2 2 2 0 NOA36 protein RP-C_C PF11800.8 EKX43612.1 - 0.14 12.2 6.1 7.7 6.6 5.5 2.2 2 0 0 2 2 2 0 Replication protein C C-terminal region Nop14 PF04147.12 EKX43612.1 - 0.16 10.2 4.3 0.17 10.1 4.3 1.0 1 0 0 1 1 1 0 Nop14-like family Zip PF02535.22 EKX43612.1 - 0.41 9.8 3.6 0.47 9.6 3.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4746 PF15928.5 EKX43612.1 - 1.3 8.4 6.2 1.7 8.0 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PPP4R2 PF09184.11 EKX43612.1 - 1.5 8.3 8.2 2 7.9 8.2 1.2 1 0 0 1 1 1 0 PPP4R2 Presenilin PF01080.17 EKX43612.1 - 4.5 5.9 4.0 5.5 5.7 4.0 1.1 1 0 0 1 1 1 0 Presenilin DUF4795 PF16043.5 EKX43613.1 - 1.2e-07 31.6 47.3 4.3e-05 23.2 8.6 3.7 2 1 1 3 3 3 2 Domain of unknown function (DUF4795) Baculo_PEP_C PF04513.12 EKX43613.1 - 0.0097 16.0 18.6 0.02 14.9 0.5 5.1 3 2 1 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus OmpH PF03938.14 EKX43613.1 - 0.033 14.5 0.1 0.033 14.5 0.1 5.0 2 2 2 4 4 4 0 Outer membrane protein (OmpH-like) Matrilin_ccoil PF10393.9 EKX43613.1 - 0.081 12.8 0.3 1.1 9.2 0.1 2.9 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin WXG100 PF06013.12 EKX43613.1 - 0.96 9.7 17.5 9.4 6.5 0.4 5.1 4 1 1 5 5 5 0 Proteins of 100 residues with WXG Apolipoprotein PF01442.18 EKX43613.1 - 1 9.2 31.2 0.12 12.3 7.0 4.4 2 2 2 4 4 4 0 Apolipoprotein A1/A4/E domain HalX PF08663.10 EKX43613.1 - 3.4 8.0 10.1 2.1 8.7 0.8 4.1 3 1 0 3 3 3 0 HalX domain WHEP-TRS PF00458.20 EKX43613.1 - 8.5 6.6 7.4 3.2 8.0 1.5 3.1 2 0 0 2 2 2 0 WHEP-TRS domain Rhodanese PF00581.20 EKX43614.1 - 2.4e-11 44.1 0.1 1.4e-10 41.6 0.1 2.2 2 1 0 2 2 2 1 Rhodanese-like domain Adeno_IVa2 PF02456.15 EKX43614.1 - 0.034 13.0 0.0 0.048 12.4 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein ABC_tran PF00005.27 EKX43614.1 - 0.068 13.7 0.1 0.14 12.7 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 EKX43614.1 - 0.091 13.0 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EKX43614.1 - 0.092 13.0 0.4 0.33 11.2 0.4 1.8 1 1 1 2 2 2 0 AAA domain ATPase_2 PF01637.18 EKX43614.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 EKX43614.1 - 0.12 12.8 0.1 0.18 12.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EKX43614.1 - 0.18 12.3 0.0 0.33 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_S10 PF00450.22 EKX43616.1 - 8.2e-67 226.4 0.0 9.4e-67 226.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF3507 PF12015.8 EKX43616.1 - 0.09 12.5 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) FGase PF05013.12 EKX43617.1 - 0.65 10.2 8.4 9.2 6.4 0.2 2.9 1 1 0 2 2 2 0 N-formylglutamate amidohydrolase Pkinase PF00069.25 EKX43618.1 - 1.3e-75 254.2 0.0 2.2e-75 253.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX43618.1 - 1.2e-39 136.2 0.0 1.8e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 EKX43618.1 - 2.1e-21 76.2 6.3 9e-12 45.3 0.5 3.0 3 0 0 3 3 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX43618.1 - 1.6e-19 68.0 9.9 8.9e-06 24.9 0.6 4.8 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EKX43618.1 - 3.6e-15 55.5 7.3 3e-08 33.4 0.2 3.5 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX43618.1 - 9.3e-13 47.0 2.5 0.003 17.4 0.0 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EKX43618.1 - 9.7e-08 31.2 5.5 0.031 13.8 0.0 4.3 4 0 0 4 4 4 3 EF hand Kdo PF06293.14 EKX43618.1 - 4.5e-07 29.4 0.1 8.3e-07 28.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.7 EKX43618.1 - 1.1e-06 28.5 1.1 0.00088 19.2 0.1 3.1 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EKX43618.1 - 3.5e-06 27.3 0.0 0.02 15.2 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain Kinase-like PF14531.6 EKX43618.1 - 4e-06 26.4 0.0 1.1e-05 24.9 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EKX43618.1 - 3.4e-05 22.8 0.0 5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EKX43618.1 - 5.6e-05 22.8 0.3 0.00011 21.9 0.3 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EKX43618.1 - 0.00027 20.0 0.0 0.00045 19.3 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EKX43618.1 - 0.063 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EKX43618.1 - 0.07 13.0 0.0 0.39 10.6 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EKX43618.1 - 0.091 12.3 0.3 0.3 10.6 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL SPARC_Ca_bdg PF10591.9 EKX43618.1 - 0.093 13.1 0.1 11 6.3 0.0 2.5 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF218 PF02698.17 EKX43619.1 - 2.2e-08 34.2 0.1 4.9e-08 33.1 0.1 1.6 1 1 0 1 1 1 1 DUF218 domain CUE PF02845.16 EKX43620.1 - 7.1e-08 32.0 0.4 1.9e-07 30.7 0.4 1.8 1 0 0 1 1 1 1 CUE domain CREPT PF16566.5 EKX43620.1 - 5.7 7.1 11.6 0.063 13.4 0.9 2.9 3 0 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour MORN PF02493.20 EKX43622.1 - 9.3e-42 138.5 57.3 5e-07 29.2 2.5 9.1 9 0 0 9 9 9 9 MORN repeat Fer4_13 PF13370.6 EKX43625.1 - 7.9e-12 45.5 1.2 1.1e-11 45.1 1.2 1.1 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 EKX43625.1 - 1.6e-09 38.4 3.0 2.9e-09 37.5 3.0 1.4 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_21 PF14697.6 EKX43625.1 - 0.0015 18.6 2.3 0.018 15.2 0.1 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EKX43625.1 - 0.0027 17.7 1.3 0.0027 17.7 1.3 2.1 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4 PF00037.27 EKX43625.1 - 0.005 16.6 8.6 0.011 15.5 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 EKX43625.1 - 0.0083 16.2 1.5 0.0083 16.2 1.5 1.8 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_7 PF12838.7 EKX43625.1 - 0.011 16.4 0.3 0.087 13.4 0.1 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 EKX43625.1 - 0.25 11.5 4.9 0.39 10.9 4.0 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain DNA_primase_lrg PF04104.14 EKX43627.1 - 0.14 11.6 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit Carb_anhydrase PF00194.21 EKX43628.1 - 9.8e-22 77.7 0.0 1.3e-21 77.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 EKX43629.1 - 5.5e-09 35.9 0.1 5.5e-09 35.9 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase RED_N PF07808.13 EKX43631.1 - 7.9e-44 150.0 14.0 5.3e-40 137.5 2.3 2.5 1 1 1 2 2 2 2 RED-like protein N-terminal region YbaB_DNA_bd PF02575.16 EKX43631.1 - 0.011 15.9 1.8 0.027 14.7 1.8 1.6 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family Kelch_4 PF13418.6 EKX43632.1 - 4.5e-21 74.6 0.4 1.2e-10 41.2 0.0 3.2 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_3 PF13415.6 EKX43632.1 - 3.6e-20 71.7 5.3 4.5e-06 26.8 0.3 3.1 2 1 1 3 3 3 3 Galactose oxidase, central domain Kelch_6 PF13964.6 EKX43632.1 - 2.2e-19 69.0 5.0 1.9e-09 37.5 0.1 3.5 2 2 2 4 4 4 3 Kelch motif Kelch_5 PF13854.6 EKX43632.1 - 2.6e-19 68.7 2.8 6.8e-09 35.5 0.1 3.7 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 EKX43632.1 - 3.8e-10 39.3 0.5 6.1e-05 22.8 0.0 3.0 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 EKX43632.1 - 1.3e-09 37.5 0.8 0.0014 18.1 0.0 3.9 4 0 0 4 4 4 2 Kelch motif EF-hand_7 PF13499.6 EKX43633.1 - 7.5e-11 42.3 0.1 2.5e-10 40.6 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX43633.1 - 8.2e-11 40.7 4.3 0.0001 21.6 0.3 3.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EKX43633.1 - 1.3e-10 40.3 2.9 2.9e-06 26.8 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 EKX43633.1 - 5.1e-09 35.2 0.6 0.0027 17.1 0.3 2.9 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX43633.1 - 2.3e-05 24.1 3.3 0.00043 20.1 0.1 3.0 2 1 1 3 3 3 2 EF-hand domain pair ACCA PF03255.14 EKX43633.1 - 0.058 13.3 0.1 1.2 9.0 0.1 2.5 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Colicin_immun PF09204.10 EKX43633.1 - 0.079 13.5 1.8 0.42 11.2 0.3 2.6 2 0 0 2 2 2 0 Bacterial self-protective colicin-like immunity Nodulin-like PF06813.13 EKX43634.1 - 0.034 13.6 3.1 0.22 11.0 0.2 2.0 2 0 0 2 2 2 0 Nodulin-like PKD_channel PF08016.12 EKX43635.1 - 5e-65 219.8 19.8 7.4e-65 219.3 19.8 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 EKX43635.1 - 3.1e-09 36.4 31.5 3.1e-09 36.4 31.5 2.2 2 1 0 2 2 2 1 Ion transport protein PrkA PF06798.12 EKX43635.1 - 0.0094 15.6 0.8 0.024 14.3 0.1 1.9 2 0 0 2 2 2 1 PrkA serine protein kinase C-terminal domain X8 PF07983.13 EKX43636.1 - 0.0011 19.6 0.0 0.002 18.8 0.0 1.4 1 0 0 1 1 1 1 X8 domain AMPK1_CBM PF16561.5 EKX43638.1 - 1.1e-18 67.2 0.3 2.2e-18 66.2 0.3 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CSTF_C PF14304.6 EKX43638.1 - 0.05 13.2 0.9 0.36 10.4 0.1 2.6 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal NESP55 PF06390.12 EKX43640.1 - 0.02 14.5 14.7 0.029 14.0 14.7 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Trypan_PARP PF05887.11 EKX43640.1 - 0.086 12.8 9.4 0.16 12.0 9.4 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Tim54 PF11711.8 EKX43640.1 - 0.47 9.2 7.7 0.59 8.9 7.7 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NEMP PF10225.9 EKX43640.1 - 1.1 8.9 2.5 1.5 8.4 2.5 1.2 1 0 0 1 1 1 0 NEMP family Presenilin PF01080.17 EKX43640.1 - 9.1 4.9 5.8 10 4.8 5.8 1.2 1 0 0 1 1 1 0 Presenilin SIR2 PF02146.17 EKX43641.1 - 2.2e-11 44.0 0.0 3.5e-11 43.4 0.0 1.3 1 1 0 1 1 1 1 Sir2 family Acatn PF13000.7 EKX43642.1 - 2.7e-118 395.9 9.7 8e-97 325.0 0.5 3.2 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 PXA PF02194.15 EKX43643.1 - 5.4e-21 75.4 0.1 5.4e-21 75.4 0.1 2.8 2 1 0 2 2 2 1 PXA domain Nexin_C PF08628.12 EKX43643.1 - 9.3e-13 48.7 0.1 9.3e-13 48.7 0.1 3.2 2 1 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 EKX43643.1 - 2.7e-07 30.6 8.5 4.1e-05 23.5 2.4 4.1 3 1 0 3 3 3 1 PX domain Acetyltransf_16 PF05301.11 EKX43644.1 - 4.6e-55 186.1 0.1 5.9e-55 185.7 0.1 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Acetyltransf_7 PF13508.7 EKX43644.1 - 0.001 19.5 0.0 0.0021 18.4 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EKX43644.1 - 0.0051 16.7 0.0 0.01 15.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EKX43644.1 - 0.022 15.0 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family 5-FTHF_cyc-lig PF01812.20 EKX43646.1 - 7e-46 156.4 0.0 7.9e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family DSS1_SEM1 PF05160.13 EKX43647.1 - 8.3e-17 61.0 17.6 1e-16 60.7 17.6 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family DUF2947 PF11163.8 EKX43647.1 - 0.0059 16.5 6.6 0.0059 16.5 6.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2947) MarR PF01047.22 EKX43647.1 - 0.17 11.9 0.3 0.29 11.1 0.3 1.3 1 0 0 1 1 1 0 MarR family Prp19 PF08606.11 EKX43648.1 - 1.6e-27 95.3 1.6 3.5e-27 94.2 1.6 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 EKX43648.1 - 1.6e-18 66.7 15.0 2.1e-05 25.2 0.3 7.5 7 0 0 7 7 7 4 WD domain, G-beta repeat zf-Nse PF11789.8 EKX43648.1 - 2.3e-06 27.3 0.0 4.4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit ANAPC4_WD40 PF12894.7 EKX43648.1 - 1.3e-05 25.4 2.5 3.1 8.2 0.0 4.4 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain U-box PF04564.15 EKX43648.1 - 0.0014 18.7 0.0 0.0047 17.1 0.0 1.9 1 0 0 1 1 1 1 U-box domain HPS3_N PF14761.6 EKX43648.1 - 0.013 15.0 0.0 3.4 7.2 0.0 2.5 2 1 0 2 2 2 0 Hermansky-Pudlak syndrome 3 Rtf2 PF04641.12 EKX43648.1 - 0.018 14.4 1.2 0.051 12.9 0.0 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger Ge1_WD40 PF16529.5 EKX43648.1 - 0.051 12.5 0.4 7.5 5.4 0.0 3.1 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein GED PF02212.18 EKX43648.1 - 0.052 13.7 0.1 0.098 12.8 0.1 1.4 1 0 0 1 1 1 0 Dynamin GTPase effector domain CENP-K PF11802.8 EKX43648.1 - 0.11 12.0 0.8 0.17 11.4 0.8 1.2 1 0 0 1 1 1 0 Centromere-associated protein K Golgin_A5 PF09787.9 EKX43648.1 - 0.26 10.7 2.3 0.39 10.1 2.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 CbiG_N PF11760.8 EKX43648.1 - 0.33 11.0 1.7 7.6 6.6 0.1 3.2 3 0 0 3 3 3 0 Cobalamin synthesis G N-terminal Hyccin PF09790.9 EKX43649.1 - 7.5e-07 28.5 0.2 1.2e-06 27.9 0.2 1.2 1 0 0 1 1 1 1 Hyccin Urb2 PF10441.9 EKX43649.1 - 0.022 14.7 0.2 0.26 11.2 0.1 2.0 1 1 1 2 2 2 0 Urb2/Npa2 family Ras PF00071.22 EKX43650.1 - 6.8e-61 204.6 0.0 8.1e-61 204.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EKX43650.1 - 9.9e-35 119.4 0.1 2.2e-34 118.2 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EKX43650.1 - 5.6e-12 45.5 0.0 6.7e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EKX43650.1 - 0.00037 19.9 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EKX43650.1 - 0.00066 19.7 0.0 0.0012 19.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EKX43650.1 - 0.0014 18.2 0.0 0.0031 17.1 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EKX43650.1 - 0.003 17.5 0.1 1.1 9.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EKX43650.1 - 0.036 14.5 0.2 0.075 13.4 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain SUIM_assoc PF16619.5 EKX43651.1 - 4e-05 23.6 0.0 4e-05 23.6 0.0 4.4 1 1 1 2 2 1 1 Unstructured region C-term to UIM in Ataxin3 DUF4045 PF13254.6 EKX43651.1 - 0.0042 16.8 21.8 0.0067 16.1 21.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4045) SLC12 PF03522.15 EKX43651.1 - 0.0074 15.4 18.7 0.017 14.2 18.7 1.6 1 0 0 1 1 1 1 Solute carrier family 12 ORC6 PF05460.13 EKX43651.1 - 0.072 12.4 17.9 0.12 11.7 17.9 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PPP4R2 PF09184.11 EKX43651.1 - 0.19 11.3 31.3 0.37 10.3 31.3 1.4 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.13 EKX43651.1 - 0.22 11.5 40.9 0.38 10.7 40.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Raftlin PF15250.6 EKX43651.1 - 0.91 8.2 22.5 1.5 7.5 22.5 1.3 1 0 0 1 1 1 0 Raftlin Trypan_PARP PF05887.11 EKX43651.1 - 1.8 8.6 25.7 3.9 7.5 25.7 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Dapper PF15268.6 EKX43651.1 - 3.1 6.6 30.2 4.4 6.1 30.2 1.1 1 0 0 1 1 1 0 Dapper Astro_capsid_p PF12226.8 EKX43651.1 - 4.7 6.3 23.9 23 4.0 0.0 2.4 2 0 0 2 2 2 0 Turkey astrovirus capsid protein DUF4638 PF15472.6 EKX43651.1 - 8.4 6.0 33.8 0.048 13.4 2.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4638) Endostatin PF06482.11 EKX43651.1 - 8.7 5.7 21.8 17 4.8 21.8 1.5 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Aminotran_4 PF01063.19 EKX43652.1 - 0.03 14.2 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 Amino-transferase class IV DUF2723 PF11028.8 EKX43653.1 - 4.9e-12 46.1 7.9 1.7e-11 44.4 7.9 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2723) SR-25 PF10500.9 EKX43653.1 - 0.041 13.5 12.9 0.07 12.7 1.6 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein NPR3 PF03666.13 EKX43653.1 - 0.9 8.3 13.4 0.041 12.7 3.3 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 PMT_2 PF13231.6 EKX43653.1 - 1.7 8.9 17.3 0.064 13.5 10.1 2.1 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Vfa1 PF08432.10 EKX43653.1 - 5.2 7.4 9.6 25 5.1 6.2 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 FGF-BP1 PF06473.12 EKX43653.1 - 6.5 6.5 8.9 0.39 10.5 2.3 2.0 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) Ion_trans PF00520.31 EKX43654.1 - 2.1e-33 115.6 4.7 2.9e-33 115.1 4.7 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX43654.1 - 5.2e-10 39.1 3.8 5.2e-10 39.1 3.8 2.7 3 0 0 3 3 3 1 Ion channel DUF2975 PF11188.8 EKX43654.1 - 0.2 11.5 0.0 0.2 11.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) Multi_Drug_Res PF00893.19 EKX43654.1 - 0.34 11.6 3.3 1.7 9.4 0.5 2.3 2 0 0 2 2 2 0 Small Multidrug Resistance protein Arf PF00025.21 EKX43655.1 - 3e-80 267.8 0.1 3.3e-80 267.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EKX43655.1 - 3.3e-14 53.1 0.0 4.6e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EKX43655.1 - 1.1e-13 51.0 0.0 1.5e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EKX43655.1 - 7.4e-13 48.4 0.0 8.2e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EKX43655.1 - 1.3e-12 47.6 1.5 1.8e-08 33.9 0.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EKX43655.1 - 3e-10 39.9 0.0 3.6e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EKX43655.1 - 1.6e-05 25.0 0.0 2.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EKX43655.1 - 0.0039 16.5 0.4 0.0069 15.7 0.4 1.6 1 1 0 1 1 1 1 6-phosphofructo-2-kinase Ribosomal_L22 PF00237.19 EKX43656.1 - 5.6e-37 126.1 0.1 8.9e-37 125.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Med9 PF07544.13 EKX43656.1 - 0.015 15.3 0.7 0.034 14.2 0.1 1.8 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 RRM_1 PF00076.22 EKX43657.1 - 6.2e-06 25.9 0.0 1.4e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EKX43657.1 - 0.0074 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phage_holin_2_4 PF16082.5 EKX43658.1 - 0.67 9.7 3.9 0.44 10.3 1.0 2.1 2 1 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Helicase_C PF00271.31 EKX43660.1 - 9.4e-15 54.9 0.0 2.3e-14 53.7 0.0 1.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EKX43661.1 - 0.01 15.6 0.1 0.013 15.3 0.1 1.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase ATPase PF06745.13 EKX43662.1 - 0.0005 19.5 0.0 0.00059 19.2 0.0 1.2 1 0 0 1 1 1 1 KaiC AAA_11 PF13086.6 EKX43662.1 - 0.0021 17.9 0.0 0.0025 17.6 0.0 1.0 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EKX43662.1 - 0.014 15.4 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 NACHT domain DEAD PF00270.29 EKX43662.1 - 0.022 14.5 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_23 PF13476.6 EKX43662.1 - 0.028 14.9 0.0 0.045 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EKX43662.1 - 0.037 13.9 0.0 0.044 13.7 0.0 1.3 1 1 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 EKX43662.1 - 0.038 13.5 0.0 0.044 13.3 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 EKX43662.1 - 0.042 13.3 0.0 0.083 12.3 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 EKX43662.1 - 0.046 14.2 0.1 0.058 13.9 0.1 1.5 1 1 0 1 1 1 0 ABC transporter SMC_N PF02463.19 EKX43662.1 - 0.05 13.0 0.0 0.05 13.0 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EKX43662.1 - 0.052 13.9 0.0 0.053 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 EKX43662.1 - 0.084 12.6 0.0 0.09 12.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EKX43662.1 - 0.093 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EKX43662.1 - 0.1 12.9 0.0 0.13 12.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 EKX43662.1 - 0.12 12.2 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Helicase ResIII PF04851.15 EKX43662.1 - 0.12 12.3 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.26 EKX43662.1 - 0.16 11.7 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain OB_NTP_bind PF07717.16 EKX43663.1 - 2.5e-20 72.6 0.2 1e-19 70.6 0.0 2.2 3 0 0 3 3 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EKX43663.1 - 5.3e-16 58.9 2.7 2.6e-15 56.6 0.0 3.1 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EKX43663.1 - 1.6e-15 57.4 0.0 7.1e-15 55.3 0.0 2.2 2 0 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EKX43663.1 - 1.3e-11 44.6 0.0 2.2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase UBA PF00627.31 EKX43663.1 - 1.9e-07 30.9 0.7 0.00091 19.1 0.1 2.7 2 0 0 2 2 2 2 UBA/TS-N domain RWD PF05773.22 EKX43663.1 - 4e-07 30.3 0.0 1.1e-06 28.9 0.0 1.9 1 0 0 1 1 1 1 RWD domain AAA_22 PF13401.6 EKX43663.1 - 0.00061 20.1 0.8 0.0039 17.5 0.8 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EKX43663.1 - 0.0016 18.8 0.0 0.0042 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EKX43663.1 - 0.026 14.6 0.0 0.13 12.2 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 EKX43663.1 - 0.031 13.3 0.0 0.057 12.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 EKX43663.1 - 0.04 13.3 0.1 0.083 12.2 0.1 1.4 1 0 0 1 1 1 0 KaiC Rad17 PF03215.15 EKX43663.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain dsRBD2 PF17842.1 EKX43663.1 - 0.36 11.0 0.0 0.36 11.0 0.0 2.7 4 0 0 4 4 4 0 Double-stranded RNA binding domain 2 DBINO PF13892.6 EKX43663.1 - 3.6 8.0 10.8 7.7 6.9 2.9 2.9 2 0 0 2 2 2 0 DNA-binding domain TarH PF02203.15 EKX43664.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue DUF3570 PF12094.8 EKX43665.1 - 0.16 10.7 0.0 0.17 10.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3570) HMG_box PF00505.19 EKX43666.1 - 4.9e-20 71.7 0.2 7.4e-20 71.1 0.2 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EKX43666.1 - 4.8e-12 46.3 0.1 7.7e-12 45.6 0.1 1.3 1 0 0 1 1 1 1 HMG-box domain Nop14 PF04147.12 EKX43667.1 - 0.0032 15.8 45.3 0.0037 15.6 45.3 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 EKX43667.1 - 0.0086 15.5 48.6 0.011 15.2 48.6 1.2 1 0 0 1 1 1 1 SDA1 DUF2151 PF10221.9 EKX43667.1 - 1.6 7.2 21.7 1.9 7.0 21.7 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator DDRGK PF09756.9 EKX43667.1 - 3.8 7.0 37.1 5 6.7 37.1 1.2 1 0 0 1 1 1 0 DDRGK domain ABC_ATPase PF09818.9 EKX43668.1 - 2.1e-47 162.0 0.0 2.3e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Predicted ATPase of the ABC class ABC_ATPase PF09818.9 EKX43669.1 - 2.2e-67 227.8 0.0 2.7e-67 227.5 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 EKX43669.1 - 0.0068 16.9 0.0 0.0078 16.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain Alpha_L_fucos PF01120.17 EKX43670.1 - 7.3e-93 311.8 2.0 9.3e-93 311.4 2.0 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase DUF4200 PF13863.6 EKX43672.1 - 0.0019 18.6 1.2 0.0019 18.6 1.2 4.3 3 2 1 4 4 4 1 Domain of unknown function (DUF4200) NPV_P10 PF05531.12 EKX43672.1 - 0.021 15.3 10.1 0.4 11.2 0.3 4.2 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein SOGA PF11365.8 EKX43672.1 - 0.46 11.6 17.4 2.5 9.3 3.5 3.3 2 2 0 3 3 3 0 Protein SOGA CENP-F_leu_zip PF10473.9 EKX43672.1 - 0.65 10.0 26.4 0.053 13.6 5.4 3.9 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bcr-Abl_Oligo PF09036.10 EKX43672.1 - 1.4 9.0 6.7 3.4 7.7 0.1 3.2 2 1 1 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain DUF4094 PF13334.6 EKX43672.1 - 2.1 8.8 8.4 1.2 9.6 3.0 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) DUF4140 PF13600.6 EKX43672.1 - 9.4 6.8 25.6 3.5 8.1 2.9 4.4 2 2 3 5 5 5 0 N-terminal domain of unknown function (DUF4140) AIM24 PF01987.17 EKX43673.1 - 1.6e-27 96.7 0.0 1.2e-12 48.1 0.0 2.0 1 1 1 2 2 2 2 Mitochondrial biogenesis AIM24 Aconitase_B_N PF11791.8 EKX43674.1 - 0.0088 16.1 0.3 1.9 8.5 0.0 2.4 2 0 0 2 2 2 2 Aconitate B N-terminal domain LNP1 PF15419.6 EKX43674.1 - 0.12 12.7 16.8 1.4 9.1 7.1 2.3 2 0 0 2 2 2 0 Leukemia NUP98 fusion partner 1 TAFH PF07531.14 EKX43674.1 - 0.6 10.3 3.2 1.6 8.9 0.4 2.5 2 0 0 2 2 2 0 NHR1 homology to TAF Lant_dehydr_C PF14028.6 EKX43674.1 - 1.4 8.4 14.5 6.5 6.2 14.2 2.1 1 1 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term DivIVA PF05103.13 EKX43674.1 - 3.6 7.7 14.4 0.077 13.1 5.2 2.6 2 1 1 3 3 3 0 DivIVA protein AIM24 PF01987.17 EKX43675.1 - 2e-16 60.4 0.0 6.3e-14 52.2 0.0 2.1 1 1 1 2 2 2 2 Mitochondrial biogenesis AIM24 TrmE_N PF10396.9 EKX43676.1 - 1.5e-37 128.4 0.0 4e-37 127.0 0.0 1.7 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 EKX43676.1 - 1.3e-26 94.1 0.1 1.7e-26 93.7 0.1 1.2 1 0 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 EKX43676.1 - 9.4e-18 64.4 0.0 1.6e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EKX43676.1 - 2.3e-07 30.5 0.0 3.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EKX43676.1 - 3.9e-06 27.0 0.0 8.2e-06 26.0 0.0 1.6 2 0 0 2 2 1 1 Dynamin family AIG1 PF04548.16 EKX43676.1 - 0.0081 15.5 0.0 0.018 14.4 0.0 1.6 2 0 0 2 2 2 1 AIG1 family AAA_28 PF13521.6 EKX43676.1 - 0.014 15.7 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EKX43676.1 - 0.017 15.6 0.0 0.029 14.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 EKX43676.1 - 0.044 13.5 0.0 0.093 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 EKX43676.1 - 0.048 14.2 0.0 0.084 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 EKX43676.1 - 0.052 12.9 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein MCM PF00493.23 EKX43676.1 - 0.061 12.4 0.0 0.13 11.3 0.0 1.5 2 0 0 2 2 2 0 MCM P-loop domain RsgA_GTPase PF03193.16 EKX43676.1 - 0.084 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 EKX43676.1 - 0.089 12.5 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain GFO_IDH_MocA PF01408.22 EKX43676.1 - 0.094 13.5 0.0 0.18 12.7 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Roc PF08477.13 EKX43676.1 - 0.12 12.6 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 EKX43676.1 - 0.13 12.4 0.0 0.37 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EKX43676.1 - 0.13 12.6 0.0 0.38 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain Mito_carr PF00153.27 EKX43678.1 - 1.5e-69 230.0 0.4 3.4e-23 81.4 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EKX43678.1 - 0.002 17.3 0.2 0.08 12.1 0.0 2.4 1 1 0 2 2 2 2 Gammaproteobacterial serine protease UAA PF08449.11 EKX43679.1 - 6.7e-29 101.0 3.4 8.1e-29 100.8 3.4 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EKX43679.1 - 2.5e-05 24.5 16.1 8.7e-05 22.7 6.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 EKX43679.1 - 0.00016 21.3 1.4 0.0002 21.0 1.4 1.2 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 EKX43679.1 - 0.0039 16.2 0.4 0.0039 16.2 0.4 1.2 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like Ribosomal_S4e PF00900.20 EKX43680.1 - 6.2e-31 106.1 0.1 1.3e-30 105.1 0.1 1.6 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.12 EKX43680.1 - 6.6e-21 74.1 5.5 6.6e-21 74.1 5.5 2.5 3 0 0 3 3 3 1 RS4NT (NUC023) domain 40S_S4_C PF16121.5 EKX43680.1 - 2.7e-09 36.5 0.1 5e-09 35.7 0.1 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus S4 PF01479.25 EKX43680.1 - 3e-06 26.8 0.0 8.7e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 EKX43680.1 - 0.0024 17.7 0.7 0.0073 16.2 0.7 1.9 1 0 0 1 1 1 1 KOW motif YabA PF06156.13 EKX43681.1 - 0.0038 17.8 0.1 0.008 16.8 0.1 1.5 1 0 0 1 1 1 1 Initiation control protein YabA ZapB PF06005.12 EKX43681.1 - 0.0054 17.2 0.0 0.0094 16.4 0.0 1.4 1 0 0 1 1 1 1 Cell division protein ZapB DivIC PF04977.15 EKX43681.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Septum formation initiator DivIVA PF05103.13 EKX43681.1 - 0.1 12.7 0.3 0.24 11.5 0.3 1.5 1 0 0 1 1 1 0 DivIVA protein NYD-SP28_assoc PF14775.6 EKX43681.1 - 0.14 12.3 2.5 0.27 11.3 2.5 1.4 1 0 0 1 1 1 0 Sperm tail C-terminal domain EF-hand_7 PF13499.6 EKX43682.1 - 1.8e-15 57.2 5.1 9.4e-11 42.0 1.6 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX43682.1 - 7.3e-15 53.3 6.6 2.6e-05 23.4 0.8 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EKX43682.1 - 2.1e-14 52.1 4.4 0.002 17.9 0.3 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 EKX43682.1 - 1.1e-08 34.8 4.9 0.00031 20.5 0.3 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EKX43682.1 - 0.0009 18.6 5.6 0.31 10.6 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 EKX43682.1 - 0.0069 16.7 0.0 0.018 15.4 0.0 1.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_10 PF14788.6 EKX43682.1 - 0.15 11.9 0.7 3.9 7.4 0.1 2.5 2 1 0 2 2 2 0 EF hand Complex1_LYR PF05347.15 EKX43684.1 - 9.1e-13 48.0 0.2 2e-12 47.0 0.2 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 EKX43684.1 - 0.018 15.6 0.1 0.027 15.1 0.1 1.3 1 0 0 1 1 1 0 Complex1_LYR-like Complex1_LYR_2 PF13233.6 EKX43684.1 - 0.075 13.8 0.1 0.11 13.3 0.1 1.3 1 0 0 1 1 1 0 Complex1_LYR-like FlxA PF14282.6 EKX43685.1 - 0.021 14.8 0.6 0.021 14.8 0.6 4.3 2 1 1 4 4 4 0 FlxA-like protein DUF5320 PF17253.2 EKX43685.1 - 4.3 8.5 0.0 4.3 8.5 0.0 4.2 3 1 1 4 4 4 0 Family of unknown function (DUF5320) Lectin_N PF03954.14 EKX43685.1 - 9 6.1 17.8 0.28 10.9 1.8 3.4 2 1 0 3 3 3 0 Hepatic lectin, N-terminal domain MORN PF02493.20 EKX43686.1 - 3.9e-13 48.4 35.8 0.00075 19.2 0.0 7.6 7 1 1 8 8 8 5 MORN repeat zf-NADH-PPase PF09297.11 EKX43686.1 - 0.054 13.2 1.7 0.13 11.9 1.7 1.7 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain FYVE PF01363.21 EKX43686.1 - 0.18 11.9 3.0 0.35 11.0 3.0 1.4 1 0 0 1 1 1 0 FYVE zinc finger 2OG-FeII_Oxy_3 PF13640.6 EKX43689.1 - 6.9e-07 30.1 0.1 1.2e-06 29.3 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 EKX43689.1 - 9.9e-05 22.7 0.7 0.0019 18.5 0.2 2.3 1 1 1 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 EKX43689.1 - 0.034 14.6 0.0 0.069 13.6 0.0 1.6 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DUF4581 PF15167.6 EKX43689.1 - 0.047 13.9 0.0 0.091 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4581) YpsA PF06908.11 EKX43689.1 - 0.1 12.6 1.3 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 YspA SLOG family Velvet PF11754.8 EKX43691.1 - 0.012 15.6 3.7 0.014 15.4 3.7 1.1 1 0 0 1 1 1 0 Velvet factor ICE2 PF08426.10 EKX43691.1 - 0.021 13.9 1.8 0.067 12.3 1.8 1.7 1 1 0 1 1 1 0 ICE2 Borrelia_P83 PF05262.11 EKX43691.1 - 0.047 12.2 18.3 0.057 11.9 18.3 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein PPL5 PF18168.1 EKX43691.1 - 0.065 12.5 13.4 0.087 12.1 13.4 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Dynactin_p62 PF05502.13 EKX43691.1 - 0.1 11.4 10.5 0.14 10.9 10.5 1.3 1 0 0 1 1 1 0 Dynactin p62 family DUF1451 PF07295.11 EKX43691.1 - 0.11 12.5 14.2 0.2 11.7 14.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon containing domain Peptidase_S46 PF10459.9 EKX43691.1 - 0.16 10.6 19.4 0.19 10.3 19.4 1.1 1 0 0 1 1 1 0 Peptidase S46 RP-C_C PF11800.8 EKX43691.1 - 0.33 11.0 5.6 0.48 10.5 5.6 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region V_ATPase_I PF01496.19 EKX43691.1 - 0.5 8.2 12.3 0.58 8.0 12.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Vfa1 PF08432.10 EKX43691.1 - 0.6 10.4 21.6 0.89 9.9 21.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CLN3 PF02487.17 EKX43691.1 - 0.89 8.5 5.1 0.99 8.4 5.1 1.2 1 0 0 1 1 1 0 CLN3 protein CDC45 PF02724.14 EKX43691.1 - 1 7.6 16.0 1.3 7.2 16.0 1.1 1 0 0 1 1 1 0 CDC45-like protein CAS_C PF12026.8 EKX43691.1 - 1.1 9.3 15.6 1.8 8.6 15.6 1.3 1 0 0 1 1 1 0 Crk-Associated Substrate C-terminal domain Hid1 PF12722.7 EKX43691.1 - 1.3 7.0 12.1 1.5 6.8 12.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FapA PF03961.13 EKX43691.1 - 1.4 7.5 15.3 1.8 7.1 15.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Presenilin PF01080.17 EKX43691.1 - 1.8 7.3 11.0 2.1 7.0 11.0 1.1 1 0 0 1 1 1 0 Presenilin MDM10 PF12519.8 EKX43691.1 - 2.3 7.0 10.6 2.7 6.7 10.6 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 AAA_11 PF13086.6 EKX43691.1 - 3.7 7.3 13.8 5.4 6.7 13.8 1.3 1 0 0 1 1 1 0 AAA domain LMBR1 PF04791.16 EKX43691.1 - 4.1 6.2 8.7 5.4 5.8 8.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Exonuc_VII_L PF02601.15 EKX43691.1 - 9 5.8 14.1 12 5.3 14.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4175 PF13779.6 EKX43691.1 - 9.8 3.9 22.2 13 3.6 22.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) RNase_J_C PF17770.1 EKX43692.1 - 0.066 14.3 0.2 4.7 8.3 0.0 2.1 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain NDC10_II PF16787.5 EKX43693.1 - 0.039 13.0 0.0 0.045 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Ammonium_transp PF00909.21 EKX43695.1 - 4.4e-114 381.3 30.8 6e-114 380.8 30.8 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3925 PF13063.6 EKX43695.1 - 0.13 12.5 0.4 0.13 12.5 0.4 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF3925) LPP PF04728.13 EKX43695.1 - 1.1 9.7 3.8 2.2 8.7 3.8 1.4 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Fer2 PF00111.27 EKX43696.1 - 4.8e-09 36.1 0.7 6.8e-09 35.6 0.7 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF4508 PF14969.6 EKX43697.1 - 0.037 14.3 3.2 3.9 7.8 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4508) SelB-wing_1 PF09105.10 EKX43697.1 - 0.042 13.8 0.2 2.5 8.1 0.0 2.7 2 0 0 2 2 2 0 Elongation factor SelB, winged helix RINT1_TIP1 PF04437.13 EKX43697.1 - 0.043 12.7 0.2 14 4.4 0.0 3.0 3 0 0 3 3 3 0 RINT-1 / TIP-1 family zf-C4 PF00105.18 EKX43697.1 - 5.7 7.5 7.9 5.1 7.6 1.1 2.6 2 0 0 2 2 2 0 Zinc finger, C4 type (two domains) DER1 PF04511.15 EKX43699.1 - 1.2e-06 28.6 0.6 1.2e-06 28.6 0.6 1.5 2 0 0 2 2 2 1 Der1-like family PRIMA1 PF16101.5 EKX43699.1 - 0.21 11.6 1.8 1 9.4 0.3 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 SAM_2 PF07647.17 EKX43700.1 - 1.8e-06 27.9 0.1 3.9e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EKX43700.1 - 6.4e-05 23.3 0.3 0.00018 21.8 0.1 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF4271 PF14093.6 EKX43700.1 - 0.0017 18.3 6.7 0.041 13.8 7.1 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4271) SAM_3 PF18016.1 EKX43700.1 - 0.03 14.1 0.2 4.8 7.1 0.0 2.5 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Ost5 PF05251.12 EKX43700.1 - 3.9 7.8 9.9 0.77 10.1 4.3 2.7 2 1 1 3 3 3 0 Oligosaccharyltransferase subunit 5 ECH_1 PF00378.20 EKX43702.1 - 0.0012 18.2 1.0 12 5.1 0.0 3.3 3 0 0 3 3 3 3 Enoyl-CoA hydratase/isomerase CAP18_C PF12153.8 EKX43702.1 - 0.06 13.2 3.5 1.1e+02 2.8 0.0 4.2 4 0 0 4 4 4 0 LPS binding domain of CAP18 (C terminal) T6SS_Vgr PF13296.6 EKX43702.1 - 4.2 7.6 9.3 54 4.0 0.2 3.3 3 0 0 3 3 3 0 Putative type VI secretion system Rhs element Vgr DOT1 PF08123.13 EKX43703.1 - 1e-12 48.1 0.0 8.8e-12 45.0 0.0 1.9 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 EKX43703.1 - 0.011 15.1 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_31 PF13847.6 EKX43703.1 - 0.046 13.5 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain IRS PF02174.17 EKX43703.1 - 0.091 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 PTB domain (IRS-1 type) Kelch_5 PF13854.6 EKX43704.1 - 3.6e-38 129.0 43.9 7.7e-10 38.5 0.1 10.3 10 0 0 10 10 10 7 Kelch motif Kelch_4 PF13418.6 EKX43704.1 - 4.8e-38 128.9 26.6 2.4e-07 30.6 0.1 9.7 8 1 1 9 9 9 7 Galactose oxidase, central domain Kelch_6 PF13964.6 EKX43704.1 - 5.5e-38 128.0 39.0 4.7e-07 29.9 0.1 9.7 9 1 1 10 10 10 8 Kelch motif Kelch_2 PF07646.15 EKX43704.1 - 2.5e-37 125.4 15.4 9.9e-07 28.5 0.1 9.5 10 0 0 10 10 10 8 Kelch motif Kelch_1 PF01344.25 EKX43704.1 - 5.7e-37 125.0 33.2 4.1e-07 29.5 0.1 10.5 10 1 0 10 10 10 8 Kelch motif Kelch_3 PF13415.6 EKX43704.1 - 3.5e-36 122.8 43.0 5e-08 33.0 0.5 10.0 10 1 0 10 10 10 7 Galactose oxidase, central domain DCP1 PF06058.13 EKX43704.1 - 2.7 7.9 5.0 46 4.0 0.1 4.2 6 0 0 6 6 6 0 Dcp1-like decapping family Ephrin_rec_like PF07699.13 EKX43705.1 - 6.8e-44 147.4 111.0 1.1e-10 41.1 11.9 8.7 5 1 4 9 9 9 9 Putative ephrin-receptor like NCD3G PF07562.14 EKX43705.1 - 2.8e-06 27.2 73.7 0.012 15.6 4.7 9.6 2 2 7 11 11 11 7 Nine Cysteines Domain of family 3 GPCR EGF_MSP1_1 PF12946.7 EKX43705.1 - 0.0027 17.7 14.2 0.015 15.3 0.3 6.2 5 1 0 5 5 5 1 MSP1 EGF domain 1 hEGF PF12661.7 EKX43705.1 - 0.45 11.2 18.9 20 6.0 0.1 7.3 5 0 0 5 5 5 0 Human growth factor-like EGF TNFR_c6 PF00020.18 EKX43705.1 - 0.95 9.9 0.1 0.64 10.5 4.0 10.7 4 3 5 10 10 10 0 TNFR/NGFR cysteine-rich region DUF4681 PF15732.5 EKX43705.1 - 1.2 9.4 3.7 27 5.0 0.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4681) zf-RING_2 PF13639.6 EKX43706.1 - 2.6e-09 37.3 16.9 2.8e-09 37.1 13.8 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EKX43706.1 - 5.2e-09 36.3 10.2 5.2e-09 36.3 10.2 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EKX43706.1 - 3.2e-05 23.9 4.9 6.1e-05 23.0 4.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 EKX43706.1 - 4.9e-05 23.1 12.8 4.9e-05 23.1 12.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EKX43706.1 - 0.0001 21.9 5.6 0.0001 21.9 5.6 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 EKX43706.1 - 0.00023 21.0 12.7 0.00054 19.9 12.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EKX43706.1 - 0.00027 20.7 14.2 0.0013 18.6 11.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX43706.1 - 0.0032 17.5 6.2 0.0032 17.5 6.2 2.2 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EKX43706.1 - 0.0054 16.6 11.7 0.018 14.9 9.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EKX43706.1 - 0.4 10.3 10.8 0.99 9.1 10.8 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 EKX43706.1 - 2.3 8.1 11.8 14 5.6 12.1 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain PHD PF00628.29 EKX43706.1 - 5.2 7.0 14.7 5 7.1 13.1 1.9 1 1 0 1 1 1 0 PHD-finger Pkinase PF00069.25 EKX43707.1 - 8.9e-68 228.5 0.0 1e-67 228.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX43707.1 - 6.9e-49 166.5 0.1 8.4e-49 166.2 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX43707.1 - 3.3e-05 23.4 0.0 5.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EKX43707.1 - 0.00022 20.1 0.0 0.00033 19.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EKX43707.1 - 0.072 12.1 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PTCB-BRCT PF12738.7 EKX43708.1 - 0.00011 22.0 0.1 0.00041 20.2 0.1 1.9 2 0 0 2 2 2 1 twin BRCT domain BRCT_2 PF16589.5 EKX43708.1 - 0.00044 20.6 0.0 0.0015 18.9 0.0 1.9 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EKX43708.1 - 0.025 14.9 0.4 0.069 13.4 0.0 1.9 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain BRCT PF00533.26 EKX43708.1 - 0.11 12.9 0.0 0.32 11.4 0.0 1.8 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain HTH_22 PF13309.6 EKX43709.1 - 0.011 15.8 0.1 0.056 13.5 0.1 2.3 1 0 0 1 1 1 0 HTH domain DUF1912 PF08930.10 EKX43709.1 - 2.4 8.4 5.4 1.9 8.7 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1912) RRM_1 PF00076.22 EKX43711.1 - 1.4e-44 149.7 2.9 5.8e-18 64.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 EKX43711.1 - 3.2e-15 57.0 0.4 7.6e-15 55.8 0.0 1.9 2 0 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.6 EKX43711.1 - 3.5e-05 23.4 1.0 0.00059 19.4 0.0 2.9 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 EKX43711.1 - 0.0097 15.8 0.1 3.2 7.6 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF1866) BRAP2 PF07576.12 EKX43711.1 - 0.013 15.7 0.4 0.46 10.7 0.1 3.0 3 1 0 3 3 3 0 BRCA1-associated protein 2 RRM_occluded PF16842.5 EKX43711.1 - 0.025 14.4 0.1 2.9 7.8 0.0 2.8 3 0 0 3 3 3 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EKX43711.1 - 0.054 13.5 0.0 5.4 7.1 0.0 3.1 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Transformer PF06495.11 EKX43711.1 - 0.21 11.7 31.9 0.34 11.0 31.9 1.3 1 0 0 1 1 1 0 Fruit fly transformer protein Apt1 PF10351.9 EKX43711.1 - 8.8 5.1 11.2 12 4.6 11.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain ABC_membrane PF00664.23 EKX43712.1 - 6.2e-67 226.1 22.4 2.5e-39 135.6 6.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EKX43712.1 - 5.3e-50 169.5 0.0 6.9e-28 97.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EKX43712.1 - 2.8e-11 43.3 8.3 4.5e-05 23.0 0.1 5.0 4 1 1 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EKX43712.1 - 0.00012 22.7 0.7 0.024 15.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EKX43712.1 - 0.00019 21.1 0.7 0.07 12.9 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EKX43712.1 - 0.00062 19.7 3.5 0.017 15.0 0.0 2.9 3 0 0 3 3 2 1 RsgA GTPase AAA_21 PF13304.6 EKX43712.1 - 0.0021 18.0 0.1 1.8 8.3 0.1 3.7 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 EKX43712.1 - 0.0033 17.2 1.2 2.2 8.0 0.0 3.1 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_16 PF13191.6 EKX43712.1 - 0.0033 17.8 0.1 1.6 9.0 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 EKX43712.1 - 0.016 14.5 0.4 0.37 10.1 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.6 EKX43712.1 - 0.028 14.7 3.5 1.2 9.4 0.1 3.3 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 EKX43712.1 - 0.035 14.2 4.1 0.41 10.7 0.2 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 EKX43712.1 - 0.043 13.9 5.4 0.83 9.7 0.1 3.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase Roc PF08477.13 EKX43712.1 - 0.049 13.8 0.3 9.5 6.5 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DEAD PF00270.29 EKX43712.1 - 0.05 13.4 0.9 6.8 6.4 0.0 3.2 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_7 PF12775.7 EKX43712.1 - 0.079 12.5 0.7 0.78 9.2 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 EKX43712.1 - 0.091 12.8 3.9 2.6 8.1 0.6 2.6 2 0 0 2 2 2 0 Dynamin family cobW PF02492.19 EKX43712.1 - 0.1 12.1 2.3 0.14 11.7 0.3 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.21 EKX43712.1 - 0.28 10.5 0.8 8.1 5.8 0.0 2.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Glycophorin_A PF01102.18 EKX43712.1 - 0.5 10.6 2.5 0.56 10.5 0.1 2.1 2 0 0 2 2 2 0 Glycophorin A TrwB_AAD_bind PF10412.9 EKX43712.1 - 1.5 7.7 4.4 1.1 8.1 0.1 2.5 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 EKX43712.1 - 2.1 7.4 4.4 1.6 7.7 0.0 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein NB-ARC PF00931.22 EKX43712.1 - 4.4 6.4 6.1 17 4.5 0.3 2.7 3 0 0 3 3 3 0 NB-ARC domain FYVE PF01363.21 EKX43713.1 - 3.7e-07 30.2 0.0 0.00029 20.9 1.0 3.2 2 1 0 2 2 2 2 FYVE zinc finger DUF2408 PF10303.9 EKX43713.1 - 0.04 14.5 5.8 0.095 13.3 5.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) MCM3AP_GANP PF16769.5 EKX43713.1 - 0.13 10.5 8.5 0.2 9.9 8.5 1.2 1 0 0 1 1 1 0 MCM3AP domain of GANP V_ATPase_I PF01496.19 EKX43713.1 - 0.98 7.3 6.1 1.4 6.7 6.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ig_Tie2_1 PF10430.9 EKX43716.1 - 0.039 14.4 1.1 2.3 8.7 0.1 2.2 1 1 1 2 2 2 0 Tie-2 Ig-like domain 1 Fun_ATP-synt_8 PF05933.13 EKX43716.1 - 0.05 13.8 0.9 0.05 13.8 0.9 3.0 3 0 0 3 3 3 0 Fungal ATP synthase protein 8 (A6L) TctA PF01970.16 EKX43716.1 - 0.13 11.0 9.1 0.16 10.6 9.1 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family S1FA PF04689.13 EKX43716.1 - 1.4 9.1 3.6 1.2 9.4 1.1 2.1 2 0 0 2 2 2 0 DNA binding protein S1FA RRM_1 PF00076.22 EKX43717.1 - 7.1e-17 61.0 0.0 1.3e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ephrin_rec_like PF07699.13 EKX43718.1 - 1e-25 89.2 90.0 4.7e-06 26.3 11.5 9.1 4 1 4 9 9 9 8 Putative ephrin-receptor like NCD3G PF07562.14 EKX43718.1 - 2.2e-13 49.9 68.8 0.027 14.4 5.4 8.5 7 2 2 9 9 9 8 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX43718.1 - 3.6e-12 46.5 68.1 0.0066 16.8 0.3 10.5 5 4 5 10 10 10 10 TNFR/NGFR cysteine-rich region Ephrin_rec_like PF07699.13 EKX43719.1 - 0.00034 20.3 52.5 0.045 13.5 6.8 5.4 3 2 1 5 5 5 4 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX43719.1 - 1.8 9.1 45.8 0.41 11.1 2.8 5.6 5 1 0 6 6 6 0 TNFR/NGFR cysteine-rich region Ephrin_rec_like PF07699.13 EKX43721.1 - 1.2e-05 24.9 302.5 0.045 13.5 8.8 28.0 16 8 12 29 29 29 18 Putative ephrin-receptor like SBBP PF06739.11 EKX43721.1 - 0.0012 18.8 27.7 0.18 11.8 0.0 5.8 6 0 0 6 6 6 4 Beta-propeller repeat Big_6 PF17936.1 EKX43721.1 - 0.033 14.5 5.0 4.1 7.7 0.4 2.7 2 0 0 2 2 2 0 Bacterial Ig domain Big_1 PF02369.16 EKX43721.1 - 2.4 8.2 11.6 11 6.1 2.2 2.9 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) Ephrin_rec_like PF07699.13 EKX43722.1 - 0.013 15.2 36.2 0.041 13.6 1.8 4.7 1 1 3 4 4 4 0 Putative ephrin-receptor like zf-C2H2_9 PF16293.5 EKX43723.1 - 0.17 11.7 7.6 0.12 12.2 0.8 3.9 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) DALR_1 PF05746.15 EKX43724.1 - 0.03 14.5 0.2 0.1 12.8 0.2 2.0 1 1 0 1 1 1 0 DALR anticodon binding domain DUF5095 PF17016.5 EKX43724.1 - 0.046 13.4 0.2 0.09 12.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5095) Ras PF00071.22 EKX43726.1 - 8.6e-63 210.8 0.3 1e-62 210.5 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EKX43726.1 - 1.6e-35 121.9 0.1 2.4e-35 121.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EKX43726.1 - 2e-13 50.2 0.1 2.5e-13 49.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EKX43726.1 - 2.9e-07 30.6 0.1 4.7e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EKX43726.1 - 7.1e-05 23.1 0.1 0.00098 19.4 0.1 2.4 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EKX43726.1 - 8.6e-05 22.5 0.1 0.017 15.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EKX43726.1 - 0.00019 21.1 0.3 0.0013 18.3 0.3 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EKX43726.1 - 0.0042 16.5 0.1 0.0066 15.8 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EKX43726.1 - 0.0078 16.6 0.1 0.016 15.6 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 EKX43726.1 - 0.011 16.2 0.2 0.02 15.4 0.2 1.7 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 EKX43726.1 - 0.023 14.4 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EKX43726.1 - 0.032 13.6 0.0 0.07 12.5 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EKX43726.1 - 0.034 13.7 0.1 0.074 12.6 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.6 EKX43726.1 - 0.036 14.1 0.0 0.087 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EKX43726.1 - 0.038 13.7 0.1 0.064 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EKX43726.1 - 0.061 13.7 0.0 2.2 8.7 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Ploopntkinase3 PF18751.1 EKX43726.1 - 0.066 13.1 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 TniB PF05621.11 EKX43726.1 - 0.08 12.3 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein FAD-SLDH PF12318.8 EKX43726.1 - 0.094 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase AAA_7 PF12775.7 EKX43726.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 EKX43726.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 EKX43726.1 - 0.16 11.7 0.8 0.27 11.0 0.5 1.6 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Ank_2 PF12796.7 EKX43727.1 - 1.3e-28 99.4 0.1 9.8e-13 48.5 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX43727.1 - 1.4e-28 98.9 1.3 3.5e-10 40.2 0.0 4.6 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EKX43727.1 - 9.5e-24 82.8 10.3 1.9e-05 24.9 0.0 6.4 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 EKX43727.1 - 3.6e-21 73.0 4.6 0.0019 18.5 0.0 6.6 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EKX43727.1 - 1.5e-19 69.8 3.0 1.7e-08 34.5 0.2 4.4 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Metallophos PF00149.28 EKX43728.1 - 3.3e-12 47.3 0.0 5e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4156 PF13698.6 EKX43728.1 - 0.12 12.7 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4156) C2 PF00168.30 EKX43729.1 - 1.2e-14 54.4 0.0 2.7e-14 53.3 0.0 1.6 2 0 0 2 2 2 1 C2 domain Glyco_hydro_2_C PF02836.17 EKX43730.1 - 1.8e-94 316.3 0.0 2.3e-94 315.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 EKX43730.1 - 1.7e-42 145.7 0.0 5.6e-33 114.6 0.0 2.5 2 0 0 2 2 2 2 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 EKX43730.1 - 3.9e-36 124.5 0.3 6.9e-36 123.7 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 EKX43730.1 - 7.2e-06 26.6 0.0 1.6e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 DUF4981 PF16353.5 EKX43730.1 - 4.8e-05 23.8 0.0 0.0002 21.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_72 PF03198.14 EKX43730.1 - 0.025 13.9 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Glucanosyltransferase BCS1_N PF08740.11 EKX43731.1 - 6.3e-25 88.2 0.0 1.1e-24 87.5 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EKX43731.1 - 1.7e-21 77.0 0.0 3.5e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX43731.1 - 0.00019 21.8 0.0 0.00043 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EKX43731.1 - 0.00021 21.0 0.0 0.00036 20.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 EKX43731.1 - 0.0027 16.9 0.0 0.0041 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EKX43731.1 - 0.0072 16.3 0.0 0.018 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EKX43731.1 - 0.022 14.9 0.0 0.046 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EKX43731.1 - 0.023 15.0 0.0 0.12 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EKX43731.1 - 0.025 14.3 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EKX43731.1 - 0.035 13.8 0.1 0.076 12.7 0.1 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 EKX43731.1 - 0.035 14.0 0.0 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 NACHT domain TIP49 PF06068.13 EKX43731.1 - 0.042 13.1 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase PF06745.13 EKX43731.1 - 0.062 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.6 EKX43731.1 - 0.094 12.3 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EKX43731.1 - 0.1 13.1 0.1 0.55 10.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EKX43731.1 - 0.15 12.6 0.0 0.31 11.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 EKX43731.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain TAF1_subA PF14929.6 EKX43732.1 - 3.3e-12 46.5 0.0 2.2e-11 43.8 0.0 2.1 1 1 0 1 1 1 1 TAF RNA Polymerase I subunit A TPR_19 PF14559.6 EKX43732.1 - 0.00025 21.5 0.4 1.2 9.7 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX43732.1 - 0.022 15.6 5.9 1.2 10.1 0.1 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Sigma70_ner PF04546.13 EKX43732.1 - 0.031 14.1 5.2 0.063 13.1 5.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Prothymosin PF03247.14 EKX43732.1 - 0.042 14.3 19.0 0.099 13.1 19.0 1.6 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF4643 PF15485.6 EKX43732.1 - 0.051 13.4 0.1 0.085 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) GATA PF00320.27 EKX43732.1 - 0.17 11.5 4.4 0.4 10.3 4.4 1.6 1 0 0 1 1 1 0 GATA zinc finger CDC45 PF02724.14 EKX43732.1 - 1.4 7.1 6.6 2.5 6.3 6.6 1.3 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.10 EKX43732.1 - 3.3 8.1 17.2 8.9 6.8 17.2 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pkinase PF00069.25 EKX43733.1 - 2.6e-70 236.8 0.0 4.3e-70 236.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX43733.1 - 1e-34 120.0 0.0 1.6e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 EKX43733.1 - 5.7e-13 48.7 0.1 2e-12 47.0 0.1 2.0 2 1 0 2 2 2 1 Cyclic nucleotide-binding domain Kinase-like PF14531.6 EKX43733.1 - 1.2e-05 24.7 0.0 0.0017 17.7 0.0 2.6 2 0 0 2 2 2 2 Kinase-like Vfa1 PF08432.10 EKX43733.1 - 0.76 10.1 7.8 1.4 9.2 7.8 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PGA2 PF07543.12 EKX43733.1 - 1.8 8.5 8.2 4.1 7.4 8.2 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 PMSR PF01625.21 EKX43734.1 - 7.1e-31 107.5 0.4 1e-30 106.9 0.4 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Shigella_OspC PF06128.11 EKX43734.1 - 0.016 14.9 0.0 0.031 14.0 0.0 1.4 1 1 0 1 1 1 0 Shigella flexneri OspC protein DUF5119 PF17145.4 EKX43734.1 - 0.09 12.7 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5119) DUF2300 PF10062.9 EKX43734.1 - 0.094 12.8 0.4 0.46 10.6 0.3 1.9 1 1 1 2 2 2 0 Predicted secreted protein (DUF2300) Ribosomal_L18_c PF14204.6 EKX43735.1 - 0.042 14.8 1.3 0.07 14.1 1.3 1.3 1 0 0 1 1 1 0 Ribosomal L18 C-terminal region Cyclin_N PF00134.23 EKX43736.1 - 1.9e-15 56.7 0.3 3.9e-15 55.7 0.3 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 EKX43736.1 - 4.2e-06 27.1 2.2 2.8e-05 24.5 0.1 2.5 1 1 1 2 2 2 1 Cyclin C-terminal domain Cyclin_C PF02984.19 EKX43736.1 - 0.00068 19.7 3.4 0.95 9.6 0.1 3.1 2 1 0 2 2 2 2 Cyclin, C-terminal domain B12D PF06522.11 EKX43736.1 - 0.17 11.7 0.5 0.44 10.4 0.0 1.9 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Peptidase_C74 PF12387.8 EKX43736.1 - 0.56 9.7 2.0 1.7 8.1 0.1 2.3 2 1 1 3 3 3 0 Pestivirus NS2 peptidase DUF2004 PF09406.10 EKX43736.1 - 2.3 8.6 6.0 9.8 6.6 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2004) adh_short_C2 PF13561.6 EKX43737.1 - 2.7e-52 177.6 0.3 5.4e-52 176.7 0.3 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EKX43737.1 - 2.8e-41 141.2 0.5 1.2e-40 139.0 0.5 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EKX43737.1 - 2.6e-07 30.7 0.1 5.2e-07 29.8 0.0 1.4 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EKX43737.1 - 0.0085 15.6 0.7 0.19 11.2 0.7 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EKX43737.1 - 0.081 12.3 0.1 0.5 9.7 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase EF-hand_1 PF00036.32 EKX43738.1 - 0.00016 21.0 5.2 0.00089 18.6 2.4 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EKX43738.1 - 0.0019 18.0 2.2 0.036 14.0 1.4 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 EKX43738.1 - 0.011 16.1 1.5 0.029 14.8 1.5 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 EKX43738.1 - 0.041 13.7 0.9 0.11 12.3 0.9 1.7 1 0 0 1 1 1 0 EF-hand domain pair PI3_PI4_kinase PF00454.27 EKX43739.1 - 2.1e-25 90.0 0.4 1.4e-18 67.6 0.6 2.1 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase Arm PF00514.23 EKX43740.1 - 4.7e-15 55.0 25.9 1e-07 31.7 0.2 8.6 11 0 0 11 11 11 3 Armadillo/beta-catenin-like repeat DRIM PF07539.12 EKX43740.1 - 0.0053 15.1 0.3 0.018 13.3 0.1 1.8 2 0 0 2 2 2 1 Down-regulated in metastasis HEAT_2 PF13646.6 EKX43740.1 - 0.0057 17.0 0.3 0.0057 17.0 0.3 4.4 4 2 0 4 4 4 1 HEAT repeats V-ATPase_H_N PF03224.14 EKX43740.1 - 0.023 14.0 0.4 14 4.9 0.0 3.3 2 2 2 4 4 4 0 V-ATPase subunit H UNC45-central PF11701.8 EKX43740.1 - 0.026 14.5 6.0 0.98 9.4 0.0 4.0 4 1 1 5 5 5 0 Myosin-binding striated muscle assembly central HEAT_EZ PF13513.6 EKX43740.1 - 0.03 14.8 14.6 0.45 11.1 0.1 5.3 4 1 1 5 5 5 0 HEAT-like repeat DUF2527 PF10736.9 EKX43741.1 - 0.015 15.1 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) Ank_2 PF12796.7 EKX43742.1 - 9.4e-18 64.6 4.0 4.7e-10 39.9 0.4 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX43742.1 - 2.6e-12 47.0 1.1 5.2e-06 26.9 0.1 3.0 1 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX43742.1 - 6.1e-12 44.6 2.0 0.00017 21.8 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EKX43742.1 - 7.8e-12 45.2 4.2 4.6e-10 39.6 0.6 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX43742.1 - 5.6e-10 39.2 2.5 0.0014 19.0 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat PP2C PF00481.21 EKX43744.1 - 5.6e-37 127.8 0.0 7.2e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EKX43744.1 - 0.0016 18.1 0.0 0.0038 16.9 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C EGF_2 PF07974.13 EKX43746.1 - 7e-51 170.3 247.9 3.4e-05 24.1 11.0 14.8 15 0 0 15 15 15 14 EGF-like domain EGF_Tenascin PF18720.1 EKX43746.1 - 6.2e-40 134.6 206.4 3e-07 30.3 8.0 15.0 15 0 0 15 15 15 13 Tenascin EGF domain I-EGF_1 PF18372.1 EKX43746.1 - 0.0029 17.7 5.1 0.0029 17.7 5.1 14.7 14 2 0 14 14 14 8 Integrin beta epidermal growth factor like domain 1 EGF PF00008.27 EKX43746.1 - 0.0055 17.0 17.9 0.0082 16.4 5.1 15.6 13 2 2 15 15 15 9 EGF-like domain hEGF PF12661.7 EKX43746.1 - 0.041 14.5 6.4 0.041 14.5 6.4 16.2 15 0 0 15 15 15 0 Human growth factor-like EGF DZR PF12773.7 EKX43747.1 - 0.14 12.2 8.0 0.29 11.2 8.0 1.6 1 1 0 1 1 1 0 Double zinc ribbon Baculo_ME53 PF06061.11 EKX43747.1 - 0.67 9.1 1.6 0.93 8.7 1.6 1.3 1 1 0 1 1 1 0 Baculoviridae ME53 DnaJ_CXXCXGXG PF00684.19 EKX43747.1 - 3.4 8.1 14.6 4.6 7.7 14.0 1.7 1 1 0 1 1 1 0 DnaJ central domain EF-hand_7 PF13499.6 EKX43748.1 - 0.0061 17.0 0.5 0.059 13.8 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX43748.1 - 0.0097 15.4 0.0 0.044 13.3 0.0 2.3 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EKX43748.1 - 0.098 12.6 0.0 0.37 10.8 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain PIN_12 PF16289.5 EKX43749.1 - 0.081 13.4 0.2 0.11 12.9 0.2 1.3 1 0 0 1 1 1 0 PIN domain HTH_19 PF12844.7 EKX43750.1 - 0.1 12.7 0.5 0.34 11.0 0.3 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain CREPT PF16566.5 EKX43751.1 - 0.00022 21.4 4.8 0.0004 20.6 4.8 1.3 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour Mer2 PF09074.10 EKX43751.1 - 0.0034 17.2 2.2 0.0067 16.3 2.2 1.5 1 0 0 1 1 1 1 Mer2 SCAMP PF04144.13 EKX43751.1 - 0.084 13.2 4.9 9.3 6.5 4.9 2.3 1 1 0 1 1 1 0 SCAMP family DivIC PF04977.15 EKX43751.1 - 0.12 12.2 1.1 0.35 10.7 1.1 1.8 1 0 0 1 1 1 0 Septum formation initiator DUF745 PF05335.13 EKX43751.1 - 0.4 10.4 4.1 0.66 9.7 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) UPF0242 PF06785.11 EKX43751.1 - 0.4 10.8 5.6 0.73 9.9 5.6 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SlyX PF04102.12 EKX43751.1 - 1 10.0 4.7 2.4 8.9 4.7 1.6 1 0 0 1 1 1 0 SlyX Tfb4 PF03850.14 EKX43752.1 - 1.8e-66 224.5 2.4 3.3e-66 223.6 2.4 1.4 1 1 0 1 1 1 1 Transcription factor Tfb4 Cupin_6 PF12852.7 EKX43752.1 - 0.048 13.4 0.0 0.11 12.1 0.0 1.8 1 1 0 1 1 1 0 Cupin Rep_fac_C PF08542.11 EKX43753.1 - 1.4e-24 86.3 0.0 3e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 EKX43753.1 - 1.5e-14 54.5 0.1 2.8e-14 53.7 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EKX43753.1 - 3.5e-14 52.9 0.2 2e-10 40.7 0.4 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA_16 PF13191.6 EKX43753.1 - 6.6e-08 33.1 0.0 5.5e-05 23.6 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EKX43753.1 - 2.4e-06 27.6 0.0 3.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EKX43753.1 - 7.5e-06 25.8 0.0 1.9e-05 24.5 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EKX43753.1 - 1.1e-05 25.8 1.6 0.029 14.6 0.1 3.1 1 1 2 3 3 3 2 AAA domain Rad17 PF03215.15 EKX43753.1 - 1.8e-05 24.8 0.0 5.3e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain Mg_chelatase PF01078.21 EKX43753.1 - 0.00019 20.9 0.1 0.0012 18.3 0.1 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EKX43753.1 - 0.00024 20.9 0.0 0.00042 20.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EKX43753.1 - 0.00024 21.0 0.0 0.00039 20.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 EKX43753.1 - 0.00041 19.8 0.0 0.18 11.2 0.0 2.4 2 0 0 2 2 2 1 Bacterial TniB protein NTPase_1 PF03266.15 EKX43753.1 - 0.00063 19.7 0.2 0.0069 16.3 0.1 2.2 1 1 1 2 2 2 1 NTPase MeaB PF03308.16 EKX43753.1 - 0.00075 18.6 0.0 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 EKX43753.1 - 0.0022 18.0 0.0 0.0055 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EKX43753.1 - 0.003 17.9 0.2 0.0092 16.3 0.2 1.9 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EKX43753.1 - 0.004 16.9 0.0 0.0082 15.9 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 EKX43753.1 - 0.0052 17.2 0.1 0.038 14.4 0.0 2.5 2 1 0 2 2 2 1 RNA helicase AAA_assoc_2 PF16193.5 EKX43753.1 - 0.0087 16.4 0.0 0.029 14.7 0.0 2.0 1 1 0 1 1 1 1 AAA C-terminal domain ABC_tran PF00005.27 EKX43753.1 - 0.015 15.8 0.0 0.053 14.0 0.0 1.8 1 1 0 1 1 1 0 ABC transporter DUF815 PF05673.13 EKX43753.1 - 0.019 14.2 0.0 0.033 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 EKX43753.1 - 0.025 14.1 0.1 0.082 12.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EKX43753.1 - 0.029 13.9 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 EKX43753.1 - 0.03 14.0 0.1 0.068 12.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 EKX43753.1 - 0.035 14.1 0.0 2.2 8.3 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit DEAD PF00270.29 EKX43753.1 - 0.038 13.8 0.2 0.62 9.8 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase DUF2075 PF09848.9 EKX43753.1 - 0.042 13.1 0.3 1.6 7.9 0.3 2.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 EKX43753.1 - 0.051 14.1 0.0 0.14 12.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 EKX43753.1 - 0.071 13.0 0.0 1.2 9.0 0.1 2.3 1 1 1 2 2 2 0 NACHT domain DUF5119 PF17145.4 EKX43753.1 - 0.071 13.0 0.0 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5119) FtsK_SpoIIIE PF01580.18 EKX43753.1 - 0.075 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_28 PF13521.6 EKX43753.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 EKX43753.1 - 0.11 11.9 0.0 0.27 10.6 0.0 1.6 1 1 0 1 1 1 0 Chromatin associated protein KTI12 TrmE_N PF10396.9 EKX43754.1 - 5.8e-34 116.9 0.0 1.5e-33 115.5 0.0 1.8 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 EKX43754.1 - 5.9e-32 111.5 0.0 3.5e-26 92.7 0.0 2.2 1 1 1 2 2 2 2 MnmE helical domain MMR_HSR1 PF01926.23 EKX43754.1 - 1.6e-18 66.8 0.0 5.6e-18 65.1 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EKX43754.1 - 5.4e-06 26.0 0.0 2.9e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EKX43754.1 - 1.1e-05 25.4 0.1 0.19 11.6 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase Arf PF00025.21 EKX43754.1 - 4.7e-05 22.9 0.9 0.017 14.6 0.2 3.1 3 0 0 3 3 3 1 ADP-ribosylation factor family Dynamin_N PF00350.23 EKX43754.1 - 4.7e-05 23.5 0.0 0.00012 22.2 0.0 1.6 1 1 0 1 1 1 1 Dynamin family 3H PF02829.14 EKX43754.1 - 0.00062 20.0 0.2 0.82 10.0 0.1 2.5 2 0 0 2 2 2 2 3H domain GTP_EFTU PF00009.27 EKX43754.1 - 0.0021 17.6 0.0 0.068 12.7 0.0 2.7 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA PF00004.29 EKX43754.1 - 0.011 16.1 0.4 2.6 8.5 0.4 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EKX43754.1 - 0.023 14.9 0.0 0.078 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain EIF_2_alpha PF07541.12 EKX43754.1 - 0.054 13.6 0.4 0.13 12.4 0.4 1.7 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit ABC_tran PF00005.27 EKX43754.1 - 0.058 13.9 0.0 0.14 12.7 0.0 1.7 1 1 0 1 1 1 0 ABC transporter Gtr1_RagA PF04670.12 EKX43754.1 - 0.13 11.6 0.1 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EKX43754.1 - 0.15 12.4 1.5 2.3 8.6 0.0 2.5 1 1 0 2 2 2 0 AAA ATPase domain WD40 PF00400.32 EKX43756.1 - 7.9e-13 48.7 7.1 0.0018 19.1 0.0 6.7 7 0 0 7 7 7 3 WD domain, G-beta repeat PWWP PF00855.17 EKX43756.1 - 8.8e-07 29.3 2.1 3.6e-06 27.3 2.1 2.1 1 1 0 1 1 1 1 PWWP domain ANAPC4_WD40 PF12894.7 EKX43756.1 - 2.1e-06 27.9 0.5 1.3 9.4 0.0 4.7 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.6 EKX43756.1 - 0.05 13.5 0.0 14 5.6 0.0 3.4 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal Frtz PF11768.8 EKX43756.1 - 0.13 10.6 0.0 0.76 8.0 0.0 2.0 1 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Spc7 PF08317.11 EKX43760.1 - 0.93 8.3 40.0 0.44 9.4 4.7 3.1 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF1877 PF08974.10 EKX43760.1 - 1.5 8.9 8.6 0.65 10.1 0.6 3.4 2 2 1 3 3 3 0 Domain of unknown function (DUF1877) NPV_P10 PF05531.12 EKX43760.1 - 4.8 7.7 22.9 0.17 12.3 0.9 4.4 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.22 EKX43760.1 - 5 7.4 29.1 1.6 9.0 9.3 4.3 3 1 1 4 4 4 0 Seryl-tRNA synthetase N-terminal domain PhoU PF01895.19 EKX43760.1 - 7.2 7.2 9.4 2.7 8.5 0.7 3.2 2 1 1 3 3 3 0 PhoU domain DUF745 PF05335.13 EKX43760.1 - 8.6 6.0 30.3 0.023 14.4 14.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF745) GAS PF13851.6 EKX43760.1 - 8.6 5.6 45.4 2.1 7.6 6.4 4.1 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding DUF5082 PF16888.5 EKX43760.1 - 9.2 6.6 26.6 2.8 8.2 9.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) Ephrin_rec_like PF07699.13 EKX43761.1 - 3.9e-52 173.8 90.1 1.4e-08 34.3 4.1 9.8 2 2 9 11 11 11 11 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX43761.1 - 9.3e-06 26.0 67.8 0.42 11.1 1.2 10.5 5 2 9 14 14 14 13 TNFR/NGFR cysteine-rich region VSP PF03302.13 EKX43761.1 - 0.0055 15.6 69.9 0.6 8.9 20.7 4.6 1 1 3 4 4 4 3 Giardia variant-specific surface protein Ank_4 PF13637.6 EKX43762.1 - 2e-07 31.4 0.1 3.3e-06 27.6 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX43762.1 - 1.5e-06 28.3 0.1 4e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX43762.1 - 4.8e-06 27.1 0.0 1.3e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX43762.1 - 1.1e-05 25.6 0.2 9.9e-05 22.6 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EKX43762.1 - 0.0039 17.6 0.1 0.012 16.0 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeat HflK_N PF12221.8 EKX43762.1 - 0.044 13.8 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 Bacterial membrane protein N terminal Ank_2 PF12796.7 EKX43763.1 - 9.8e-18 64.5 1.5 8.1e-12 45.6 0.1 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX43763.1 - 1.9e-11 43.1 0.6 0.0012 19.2 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EKX43763.1 - 5.6e-11 42.4 0.2 0.0057 17.0 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EKX43763.1 - 8.2e-09 35.8 0.1 2.5e-06 27.9 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX43763.1 - 2.9e-08 33.8 0.6 3.4e-06 27.2 0.3 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Collagen PF01391.18 EKX43764.1 - 2.5e-09 36.7 31.5 5.3e-09 35.7 31.5 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF839 PF05787.13 EKX43766.1 - 3e-20 72.9 2.1 5e-20 72.2 2.1 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF839) SGL PF08450.12 EKX43766.1 - 0.022 14.4 0.6 2.6 7.6 0.1 3.3 3 1 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region Prefoldin_2 PF01920.20 EKX43767.1 - 1.5e-09 37.8 12.2 3e-09 36.8 12.2 1.5 1 1 0 1 1 1 1 Prefoldin subunit CotJB PF12652.7 EKX43767.1 - 0.015 15.5 0.7 0.034 14.3 0.7 1.6 1 0 0 1 1 1 0 CotJB protein DUF4446 PF14584.6 EKX43767.1 - 0.07 13.1 3.6 0.72 9.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF5370 PF17340.2 EKX43767.1 - 0.092 12.6 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5370) DUF4140 PF13600.6 EKX43767.1 - 0.12 12.8 1.2 1.5 9.3 0.0 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) BST2 PF16716.5 EKX43767.1 - 0.67 10.6 13.7 0.3 11.7 1.2 2.4 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Fib_alpha PF08702.10 EKX43767.1 - 2.8 8.1 8.6 16 5.7 8.6 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Phasin PF05597.11 EKX43767.1 - 4.9 7.2 8.2 1.2 9.2 2.7 2.0 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) YlqD PF11068.8 EKX43767.1 - 6.1 7.2 14.0 41 4.6 14.1 1.9 1 1 0 1 1 1 0 YlqD protein PspA_IM30 PF04012.12 EKX43767.1 - 7.9 6.0 13.0 4.1 6.9 3.3 2.2 2 0 0 2 2 2 0 PspA/IM30 family Ig_2 PF13895.6 EKX43768.1 - 0.007 16.7 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin domain DUF3552 PF12072.8 EKX43769.1 - 0.0095 15.4 13.8 0.0095 15.4 13.8 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF3552) ERM PF00769.19 EKX43769.1 - 0.01 15.6 17.2 0.012 15.5 17.2 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HOOK PF05622.12 EKX43769.1 - 0.28 9.3 19.3 0.53 8.4 16.7 1.9 1 1 0 1 1 1 0 HOOK protein SlyX PF04102.12 EKX43769.1 - 0.28 11.8 17.9 0.35 11.5 3.3 3.2 1 1 2 3 3 3 0 SlyX HAUS-augmin3 PF14932.6 EKX43769.1 - 0.36 10.4 20.1 0.021 14.4 11.8 1.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Golgin_A5 PF09787.9 EKX43769.1 - 0.65 9.4 17.6 0.88 9.0 17.6 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 FlaC_arch PF05377.11 EKX43769.1 - 1 9.8 9.2 0.29 11.6 0.7 3.2 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 EKX43769.1 - 1.9 7.8 11.7 2.9 7.1 11.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 EKX43769.1 - 2.1 7.1 21.4 13 4.5 21.5 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein Fez1 PF06818.15 EKX43769.1 - 3.4 8.1 21.3 54 4.2 21.5 2.2 1 1 0 1 1 1 0 Fez1 ParD_antitoxin PF03693.14 EKX43769.1 - 3.8 8.0 7.8 1.4 9.4 2.5 2.7 1 1 2 3 3 3 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH Atg14 PF10186.9 EKX43769.1 - 4.5 6.3 16.8 13 4.7 16.9 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 EKX43769.1 - 5.6 4.8 7.4 7.8 4.3 7.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF16 PF01519.16 EKX43769.1 - 8.1 7.0 12.1 1.4e+03 -0.2 12.1 2.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 Macoilin PF09726.9 EKX43769.1 - 8.4 4.8 19.7 15 4.0 19.7 1.4 1 0 0 1 1 1 0 Macoilin family DUF2730 PF10805.8 EKX43769.1 - 8.5 6.5 9.7 2.5 8.2 3.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) AAA_13 PF13166.6 EKX43769.1 - 9 4.8 13.8 32 3.0 13.8 1.7 1 1 0 1 1 1 0 AAA domain Cnn_1N PF07989.11 EKX43769.1 - 9.3 6.5 16.7 17 5.6 10.7 3.0 1 1 0 2 2 2 0 Centrosomin N-terminal motif 1 UPF0242 PF06785.11 EKX43769.1 - 9.4 6.3 17.8 61 3.6 17.8 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SHNi-TPR PF10516.9 EKX43771.1 - 1.8e-06 27.3 0.4 8.5e-06 25.1 0.0 2.4 2 0 0 2 2 2 1 SHNi-TPR GA PF01468.17 EKX43771.1 - 0.09 13.1 0.1 0.3 11.4 0.1 1.8 1 0 0 1 1 1 0 GA module TPR_2 PF07719.17 EKX43772.1 - 5e-22 76.2 10.8 0.0005 20.0 0.0 10.0 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 EKX43772.1 - 1.1e-18 66.1 12.0 5.2e-06 26.1 0.0 8.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 EKX43772.1 - 4.2e-17 61.4 22.8 0.017 15.9 0.0 9.1 6 2 4 10 10 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 EKX43772.1 - 2.5e-16 59.9 24.8 1.7e-05 25.2 0.1 7.9 5 2 2 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 EKX43772.1 - 1.6e-13 51.0 15.4 0.45 11.2 2.1 7.3 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 EKX43772.1 - 5.4e-12 44.9 13.6 0.039 14.2 0.0 8.7 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 EKX43772.1 - 3.2e-09 36.8 17.1 3.5 8.4 0.1 9.8 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_17 PF13431.6 EKX43772.1 - 2.4e-08 33.8 0.5 1.2 9.7 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX43772.1 - 8.3e-08 31.8 6.8 0.29 10.8 0.0 6.6 7 0 0 7 7 7 1 TPR repeat TPR_12 PF13424.6 EKX43772.1 - 2.6e-07 30.8 27.6 0.067 13.5 2.7 7.1 5 4 2 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 EKX43772.1 - 6.8e-07 29.4 13.6 0.028 14.6 0.8 6.0 5 1 2 7 7 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 EKX43772.1 - 5.5e-05 22.5 13.9 0.06 12.6 1.6 4.5 1 1 3 5 5 5 2 Tetratricopeptide repeat DUF3856 PF12968.7 EKX43772.1 - 0.00029 20.9 5.8 3 7.9 0.1 4.8 5 1 0 5 5 4 2 Domain of Unknown Function (DUF3856) ANAPC3 PF12895.7 EKX43772.1 - 0.0029 17.8 12.0 3.7 7.8 0.6 5.1 5 1 0 6 6 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EKX43772.1 - 0.0034 17.3 19.9 0.061 13.4 0.1 7.6 10 0 0 10 10 9 1 Tetratricopeptide repeat ChAPs PF09295.10 EKX43772.1 - 0.016 14.2 0.6 1.9 7.4 0.0 3.0 2 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Clathrin PF00637.20 EKX43772.1 - 0.024 14.5 0.3 0.24 11.2 0.0 2.4 2 0 0 2 2 2 0 Region in Clathrin and VPS SNAP PF14938.6 EKX43772.1 - 0.072 12.5 15.3 0.078 12.4 9.2 3.8 3 2 0 3 3 3 0 Soluble NSF attachment protein, SNAP Coatomer_E PF04733.14 EKX43772.1 - 0.2 11.1 0.1 0.2 11.1 0.1 3.2 3 1 0 3 3 3 0 Coatomer epsilon subunit TPR_21 PF09976.9 EKX43772.1 - 0.31 10.7 14.0 0.15 11.8 0.2 4.3 3 2 1 4 4 4 0 Tetratricopeptide repeat-like domain RPN7 PF10602.9 EKX43772.1 - 0.33 10.6 2.6 1.5 8.5 0.0 3.1 3 1 0 4 4 4 0 26S proteasome subunit RPN7 PEP-utilisers_N PF05524.13 EKX43772.1 - 0.74 10.0 9.6 0.32 11.2 0.7 3.7 2 2 2 4 4 4 0 PEP-utilising enzyme, N-terminal TPR_2 PF07719.17 EKX43773.1 - 3.5e-22 76.7 10.5 0.00048 20.0 0.0 10.0 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 EKX43773.1 - 1.4e-18 65.8 11.7 5e-06 26.1 0.0 8.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 EKX43773.1 - 3.2e-16 58.6 22.4 0.016 16.0 0.0 9.1 6 2 4 10 10 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 EKX43773.1 - 4.9e-16 59.0 24.2 6.6e-05 23.3 0.0 7.9 5 2 2 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 EKX43773.1 - 3.7e-14 53.1 15.0 0.43 11.3 2.1 7.3 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 EKX43773.1 - 8.2e-12 44.4 13.0 0.038 14.2 0.0 8.5 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 EKX43773.1 - 7.4e-09 35.7 15.5 6.9 7.5 0.0 9.8 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX43773.1 - 2.1e-08 34.0 0.5 1.2 9.7 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX43773.1 - 2.2e-07 30.4 5.7 0.28 10.9 0.0 6.6 7 0 0 7 7 7 1 TPR repeat TPR_12 PF13424.6 EKX43773.1 - 4e-07 30.2 27.2 0.062 13.6 2.7 7.0 5 4 2 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 EKX43773.1 - 6.7e-07 29.4 13.3 0.027 14.6 0.8 5.8 5 1 2 7 7 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 EKX43773.1 - 2.7e-05 23.5 13.6 0.12 11.5 4.1 4.5 1 1 2 4 4 4 2 Tetratricopeptide repeat DUF3856 PF12968.7 EKX43773.1 - 0.00015 21.9 5.0 2.9 7.9 0.1 4.8 4 2 0 4 4 4 2 Domain of Unknown Function (DUF3856) ANAPC3 PF12895.7 EKX43773.1 - 0.0019 18.4 12.1 3.6 7.9 0.6 5.2 5 1 0 6 6 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EKX43773.1 - 0.0044 17.0 19.3 0.059 13.4 0.1 7.6 10 0 0 10 10 9 1 Tetratricopeptide repeat ChAPs PF09295.10 EKX43773.1 - 0.016 14.2 1.7 1.9 7.4 0.0 3.0 2 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Clathrin PF00637.20 EKX43773.1 - 0.022 14.6 0.3 0.23 11.3 0.0 2.4 2 0 0 2 2 2 0 Region in Clathrin and VPS Coatomer_E PF04733.14 EKX43773.1 - 0.033 13.6 0.1 0.033 13.6 0.1 3.2 3 1 0 3 3 3 0 Coatomer epsilon subunit SNAP PF14938.6 EKX43773.1 - 0.062 12.7 14.5 0.085 12.3 8.5 3.9 3 2 0 3 3 3 0 Soluble NSF attachment protein, SNAP RPN7 PF10602.9 EKX43773.1 - 0.13 11.9 1.6 1.5 8.5 0.0 3.1 2 1 0 2 2 2 0 26S proteasome subunit RPN7 TPR_21 PF09976.9 EKX43773.1 - 0.3 10.8 13.7 0.14 11.9 0.2 4.3 3 2 1 4 4 4 0 Tetratricopeptide repeat-like domain PEP-utilisers_N PF05524.13 EKX43773.1 - 0.51 10.5 9.3 1.1 9.5 2.7 3.7 2 2 0 2 2 2 0 PEP-utilising enzyme, N-terminal Ead_Ea22 PF13935.6 EKX43773.1 - 3.3 8.4 5.4 1.9 9.2 0.0 2.9 2 1 0 2 2 2 0 Ead/Ea22-like protein Rdx PF10262.9 EKX43774.1 - 0.0054 16.9 0.0 0.0064 16.7 0.0 1.1 1 0 0 1 1 1 1 Rdx family FoP_duplication PF13865.6 EKX43775.1 - 1.3e-10 41.6 19.4 1.3e-10 41.6 19.4 3.2 1 1 1 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 dNK PF01712.19 EKX43776.1 - 2e-51 174.8 0.0 2.8e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 EKX43776.1 - 8.4e-05 23.1 0.3 0.0015 19.1 0.3 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EKX43776.1 - 0.00078 19.6 0.0 0.0064 16.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EKX43776.1 - 0.008 15.9 0.0 0.085 12.5 0.0 2.3 3 0 0 3 3 3 1 Thymidylate kinase AAA_17 PF13207.6 EKX43776.1 - 0.014 15.8 0.0 0.17 12.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.6 EKX43776.1 - 0.043 13.6 0.3 0.061 13.1 0.3 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system TENA_THI-4 PF03070.16 EKX43777.1 - 8.6e-25 87.8 0.0 1e-24 87.6 0.0 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family ORC4_C PF14629.6 EKX43777.1 - 0.12 11.8 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus DUF2187 PF09953.9 EKX43778.1 - 0.0017 18.3 0.1 0.003 17.5 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2187) CFAP91 PF14738.6 EKX43779.1 - 0.0002 21.5 2.0 0.00023 21.3 2.0 1.0 1 0 0 1 1 1 1 Cilia- and flagella-associated protein 91 DUF4809 PF16067.5 EKX43779.1 - 0.017 15.3 0.2 0.023 14.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4809) Ion_trans_2 PF07885.16 EKX43780.1 - 3.3e-11 43.0 5.0 3.3e-11 43.0 5.0 2.1 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 EKX43780.1 - 1.2e-05 24.6 17.8 0.0016 17.7 13.4 2.8 2 1 0 2 2 2 2 Ion transport protein SK_channel PF03530.14 EKX43780.1 - 0.00012 22.0 0.0 0.00012 22.0 0.0 2.3 3 0 0 3 3 3 1 Calcium-activated SK potassium channel Epimerase PF01370.21 EKX43781.1 - 4.3e-16 59.1 0.0 1.5e-13 50.8 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EKX43781.1 - 1.9e-15 56.6 0.0 3e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EKX43781.1 - 1.2e-11 44.9 0.0 2.8e-11 43.6 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EKX43781.1 - 1.9e-09 37.4 0.0 2.8e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EKX43781.1 - 3.8e-08 33.2 0.0 2.5e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 EKX43781.1 - 5.3e-08 32.3 0.0 1.6e-06 27.5 0.1 2.5 2 1 0 2 2 2 1 Male sterility protein adh_short PF00106.25 EKX43781.1 - 0.045 13.2 0.0 0.1 12.0 0.0 1.5 2 0 0 2 2 2 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 EKX43781.1 - 0.055 12.6 0.0 0.32 10.1 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain KR PF08659.10 EKX43781.1 - 0.073 13.0 0.0 0.24 11.3 0.0 1.8 1 1 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 EKX43781.1 - 0.088 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Bap31 PF05529.12 EKX43782.1 - 2.7e-10 40.2 0.1 2.7e-10 40.2 0.1 1.5 2 0 0 2 2 2 1 Bap31/Bap29 transmembrane region UPF0242 PF06785.11 EKX43782.1 - 0.0033 17.6 2.7 0.0047 17.1 2.7 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus bZIP_2 PF07716.15 EKX43782.1 - 0.04 14.0 1.8 0.04 14.0 1.8 3.2 3 1 0 3 3 3 0 Basic region leucine zipper Ammonium_transp PF00909.21 EKX43782.1 - 0.04 12.6 0.0 0.074 11.7 0.0 1.3 1 0 0 1 1 1 0 Ammonium Transporter Family DUF3810 PF12725.7 EKX43782.1 - 0.056 12.8 0.0 0.075 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Sas6_CC PF18594.1 EKX43782.1 - 0.063 13.1 1.3 0.063 13.1 1.3 2.3 3 0 0 3 3 3 0 Sas6/XLF/XRCC4 coiled-coil domain DUF1689 PF07954.11 EKX43782.1 - 0.1 13.0 1.0 2 8.8 1.0 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1689) Mu-like_Pro PF10123.9 EKX43782.1 - 0.12 11.9 2.0 0.18 11.4 2.0 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein Vut_1 PF02592.15 EKX43782.1 - 0.14 12.5 1.0 6.2 7.1 0.0 2.1 1 1 1 2 2 2 0 Putative vitamin uptake transporter MAP17 PF15807.5 EKX43782.1 - 0.22 11.8 2.1 0.4 10.9 1.6 1.7 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 VEK-30 PF12107.8 EKX43782.1 - 0.32 10.9 0.4 0.32 10.9 0.4 2.8 3 0 0 3 3 3 0 Plasminogen (Pg) ligand in fibrinolytic pathway Cep57_CLD_2 PF14197.6 EKX43782.1 - 0.34 11.0 15.6 0.35 11.0 4.2 3.4 2 1 2 4 4 4 0 Centrosome localisation domain of PPC89 DivIC PF04977.15 EKX43782.1 - 6.4 6.6 9.3 13 5.6 0.6 2.9 2 1 1 3 3 3 0 Septum formation initiator Ank PF00023.30 EKX43783.1 - 1.7e-11 44.0 3.3 0.00011 22.5 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EKX43783.1 - 4e-09 36.8 0.1 1.2e-08 35.3 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX43783.1 - 1.7e-08 35.0 0.0 4.3e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX43783.1 - 7.8e-08 32.4 0.5 4.1e-07 30.2 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX43783.1 - 2.3e-06 27.5 0.7 0.12 13.0 0.2 3.0 2 0 0 2 2 2 2 Ankyrin repeat TMF_TATA_bd PF12325.8 EKX43785.1 - 0.00051 20.2 6.8 0.00051 20.2 6.8 7.8 3 2 6 9 9 9 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 EKX43785.1 - 0.0024 17.8 10.3 0.0024 17.8 10.3 9.2 4 2 5 10 10 10 4 TATA element modulatory factor 1 DNA binding CLZ PF16526.5 EKX43785.1 - 0.0032 17.8 8.3 0.0032 17.8 8.3 8.2 5 1 3 8 8 8 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HEPN_AbiU2 PF18734.1 EKX43785.1 - 0.24 10.9 9.4 0.14 11.6 6.2 2.4 2 1 0 2 2 2 0 AbiU2 L27_2 PF09045.10 EKX43785.1 - 3.1 7.8 8.9 13 5.8 0.9 3.6 3 0 0 3 3 3 0 L27_2 Pkinase PF00069.25 EKX43787.1 - 1.6e-37 129.3 0.0 1.8e-37 129.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX43787.1 - 4e-36 124.6 0.0 4.5e-36 124.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX43787.1 - 3.3e-05 22.9 0.0 7.1e-05 21.8 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EKX43787.1 - 0.00011 22.2 0.0 0.00053 20.0 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX43787.1 - 0.00045 19.6 0.0 0.0006 19.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EKX43787.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.5 1 1 0 1 1 1 0 Kinase-like RIO1 PF01163.22 EKX43787.1 - 0.039 13.6 0.1 0.13 11.8 0.1 1.8 1 1 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 EKX43787.1 - 0.067 12.2 0.0 0.096 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 EKX43787.1 - 0.075 12.6 0.0 0.64 9.6 0.0 2.0 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PDZ_6 PF17820.1 EKX43789.1 - 1.5e-10 40.8 0.0 2e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX43789.1 - 6.4e-09 36.0 0.1 8.4e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX43789.1 - 4.7e-08 33.2 0.0 6.6e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX43789.1 - 0.0005 20.0 0.0 0.00082 19.3 0.0 1.4 1 0 0 1 1 1 1 Tricorn protease PDZ domain NAD_kinase PF01513.21 EKX43791.1 - 5.6e-30 104.5 0.1 6e-30 104.4 0.1 1.0 1 0 0 1 1 1 1 ATP-NAD kinase Nop25 PF09805.9 EKX43792.1 - 4.3e-16 59.6 12.7 4.3e-16 59.6 12.7 2.1 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) Collagen PF01391.18 EKX43793.1 - 2.9e-08 33.3 17.0 6.5e-08 32.2 17.0 1.5 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) NleF_casp_inhib PF16809.5 EKX43793.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 NleF caspase inhibitor Torus PF16131.5 EKX43794.1 - 5.9e-22 78.4 1.3 1.6e-21 77.1 1.3 1.8 1 0 0 1 1 1 1 Torus domain WW PF00397.26 EKX43794.1 - 2.8e-07 30.5 2.5 5.7e-07 29.5 2.5 1.5 1 0 0 1 1 1 1 WW domain RRM_1 PF00076.22 EKX43794.1 - 3.6e-05 23.5 0.1 6.5e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EKX43794.1 - 0.00081 19.4 3.7 0.0026 17.8 3.7 2.0 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EKX43794.1 - 0.011 15.5 1.7 0.011 15.5 1.7 1.8 2 0 0 2 2 2 0 CCCH-type zinc finger DUF4523 PF15023.6 EKX43794.1 - 0.034 14.0 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) DUF1980 PF09323.10 EKX43795.1 - 0.17 11.8 0.1 0.47 10.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) MFAP1 PF06991.11 EKX43796.1 - 0.27 11.1 0.4 0.35 10.7 0.4 1.1 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing WD40 PF00400.32 EKX43798.1 - 1.6e-39 133.2 14.8 2.8e-08 34.3 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX43798.1 - 1e-13 51.4 0.1 0.00068 19.9 0.0 5.2 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EKX43798.1 - 0.00019 21.4 0.0 0.16 11.8 0.0 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A VID27 PF08553.10 EKX43798.1 - 0.015 14.3 0.0 2.5 7.1 0.0 2.4 2 1 1 3 3 3 0 VID27 C-terminal WD40-like domain PQQ PF01011.21 EKX43798.1 - 0.028 14.3 0.2 11 6.1 0.0 4.2 5 0 0 5 5 5 0 PQQ enzyme repeat Formyl_trans_C PF02911.18 EKX43798.1 - 0.076 13.3 0.0 0.45 10.8 0.0 2.2 2 0 0 2 2 2 0 Formyl transferase, C-terminal domain TRAPPC10 PF12584.8 EKX43799.1 - 3.8e-06 26.7 0.0 5.8e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_2 PF07719.17 EKX43800.1 - 2.2e-08 33.6 6.2 1.2 9.4 0.0 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX43800.1 - 1.1e-07 32.0 8.0 0.033 14.5 0.1 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX43800.1 - 0.00044 20.7 0.2 37 4.9 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EKX43800.1 - 0.0012 18.5 1.9 4.1 7.4 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX43800.1 - 0.002 18.2 5.7 9 6.8 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat F-box PF00646.33 EKX43800.1 - 0.035 14.0 0.0 0.17 11.8 0.0 2.3 1 0 0 1 1 1 0 F-box domain TPR_7 PF13176.6 EKX43800.1 - 0.04 13.9 2.1 21 5.5 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4363 PF14276.6 EKX43800.1 - 0.11 12.6 0.1 0.44 10.7 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) TPR_14 PF13428.6 EKX43800.1 - 0.29 12.1 4.8 8.9 7.4 0.2 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX43800.1 - 0.42 10.9 9.1 0.74 10.1 0.4 4.0 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF1517 PF07466.11 EKX43801.1 - 2.9e-44 151.4 0.6 3.8e-44 151.0 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) CA_like PF10563.9 EKX43801.1 - 0.17 11.7 0.0 0.29 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative carbonic anhydrase PAPS_reduct PF01507.19 EKX43802.1 - 1.6e-38 132.4 0.0 2.6e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF4477 PF14780.6 EKX43803.1 - 1.5e-15 57.4 3.0 2.8e-15 56.5 3.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) Med31 PF05669.12 EKX43804.1 - 8.9e-36 121.8 3.8 9.9e-36 121.6 3.8 1.0 1 0 0 1 1 1 1 SOH1 Syndecan PF01034.20 EKX43805.1 - 0.00048 20.0 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 Syndecan domain SK_channel PF03530.14 EKX43812.1 - 4.5e-05 23.4 0.2 0.092 12.7 0.0 2.6 2 0 0 2 2 2 2 Calcium-activated SK potassium channel Ion_trans_2 PF07885.16 EKX43812.1 - 0.00028 20.8 3.8 0.0011 18.9 3.8 2.0 1 0 0 1 1 1 1 Ion channel SLATT_6 PF18169.1 EKX43812.1 - 0.037 13.6 0.2 0.086 12.4 0.2 1.6 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 Fer4_8 PF13183.6 EKX43812.1 - 0.039 14.4 0.9 0.12 12.9 0.9 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain DUF16 PF01519.16 EKX43812.1 - 0.057 13.9 5.5 5.9 7.4 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function DUF16 EF-hand_8 PF13833.6 EKX43812.1 - 0.13 12.1 0.1 0.7 9.8 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair Myc_N PF01056.18 EKX43812.1 - 1.2 9.0 9.8 0.19 11.6 6.0 1.5 2 0 0 2 2 2 0 Myc amino-terminal region DrsE_2 PF13686.6 EKX43813.1 - 0.33 10.8 1.7 5 7.0 0.0 2.2 1 1 1 2 2 2 0 DsrE/DsrF/DrsH-like family GWT1 PF06423.12 EKX43814.1 - 4.4e-15 56.1 6.0 1.4e-07 31.7 0.5 3.0 2 2 1 3 3 3 2 GWT1 Abhydrolase_2 PF02230.16 EKX43816.1 - 5.3e-51 173.5 0.0 6.2e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 EKX43816.1 - 8.8e-09 35.3 0.0 2.2e-08 34.0 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 EKX43816.1 - 1.1e-07 31.6 0.0 1.4e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EKX43816.1 - 4.3e-07 29.6 0.2 2.1e-05 24.1 0.0 2.1 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EKX43816.1 - 8.3e-07 29.1 0.0 0.0013 18.6 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EKX43816.1 - 3.5e-06 26.4 1.6 0.014 14.7 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EKX43816.1 - 1e-05 26.3 0.0 0.0001 23.0 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EKX43816.1 - 9.4e-05 22.2 0.3 0.023 14.3 0.1 2.9 2 1 1 3 3 3 1 alpha/beta hydrolase fold DUF2974 PF11187.8 EKX43816.1 - 0.0012 18.5 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 EKX43816.1 - 0.0012 18.6 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 EKX43816.1 - 0.0023 17.6 0.0 0.0029 17.3 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Cutinase PF01083.22 EKX43816.1 - 0.048 13.6 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 Cutinase PAF-AH_p_II PF03403.13 EKX43816.1 - 0.066 11.7 0.1 0.77 8.2 0.0 2.0 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II LIP PF03583.14 EKX43816.1 - 0.09 12.1 0.0 0.61 9.3 0.0 2.0 1 1 1 2 2 2 0 Secretory lipase BAAT_C PF08840.11 EKX43816.1 - 0.13 12.2 0.1 3.6 7.4 0.0 2.5 2 1 1 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.20 EKX43816.1 - 0.2 11.8 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Mucin15 PF15672.5 EKX43818.1 - 6 6.3 9.0 1.7 8.0 5.5 1.7 1 1 1 2 2 2 0 Cell-membrane associated Mucin15 Pkinase PF00069.25 EKX43819.1 - 5.1e-54 183.4 0.0 6.3e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX43819.1 - 1.7e-42 145.6 0.0 2e-42 145.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX43819.1 - 4.1e-07 29.6 0.0 6e-07 29.1 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EKX43819.1 - 0.002 17.0 0.1 0.0046 15.8 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 EKX43819.1 - 0.11 11.4 0.3 2.9 6.7 0.1 2.0 2 0 0 2 2 2 0 Haspin like kinase domain EF-hand_7 PF13499.6 EKX43820.1 - 9.4e-18 64.4 0.5 3.4e-09 37.0 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX43820.1 - 4e-16 57.3 5.4 4.1e-07 29.1 0.1 4.4 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 EKX43820.1 - 1.6e-13 49.4 5.1 1e-05 25.1 0.3 4.3 4 2 1 5 5 5 2 EF-hand domain EF-hand_5 PF13202.6 EKX43820.1 - 2.9e-11 42.3 2.1 0.00025 20.4 0.2 4.0 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 EKX43820.1 - 1.1e-09 37.9 0.4 0.093 12.6 0.0 4.8 2 1 2 5 5 5 3 EF-hand domain pair EF-hand_like PF09279.11 EKX43820.1 - 0.0016 18.8 0.8 0.33 11.5 0.1 2.2 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_10 PF14788.6 EKX43820.1 - 0.008 16.0 4.3 2 8.3 0.5 3.3 3 1 0 3 3 3 2 EF hand Caleosin PF05042.13 EKX43820.1 - 0.016 15.2 0.2 0.8 9.6 0.0 2.3 2 0 0 2 2 2 0 Caleosin related protein p25-alpha PF05517.12 EKX43820.1 - 0.037 14.2 0.3 0.26 11.4 0.0 2.1 2 1 0 2 2 2 0 p25-alpha MotY_N PF18393.1 EKX43820.1 - 0.041 14.0 0.1 2.8 8.1 0.0 2.1 2 0 0 2 2 2 0 MotY N-terminal domain EF-hand_9 PF14658.6 EKX43820.1 - 0.058 13.7 0.1 0.21 11.9 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain S_100 PF01023.19 EKX43820.1 - 0.059 13.1 3.2 9.7 6.0 0.5 3.4 4 0 0 4 4 4 0 S-100/ICaBP type calcium binding domain SPARC_Ca_bdg PF10591.9 EKX43820.1 - 0.097 13.0 1.3 13 6.1 0.1 2.5 1 1 2 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3349 PF11829.8 EKX43820.1 - 0.11 13.2 0.4 51 4.7 0.0 2.7 1 1 3 4 4 4 0 Protein of unknown function (DUF3349) EF-hand_13 PF17958.1 EKX43820.1 - 0.12 12.2 0.0 1.7 8.5 0.0 2.5 2 1 1 3 3 3 0 EF-hand domain WD40 PF00400.32 EKX43821.1 - 5e-17 62.0 16.4 0.00074 20.3 0.1 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX43821.1 - 4.1e-11 43.0 4.3 1.4e-06 28.5 0.4 4.9 3 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EKX43821.1 - 3.9e-06 25.8 0.5 0.055 12.1 0.1 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EKX43821.1 - 0.041 12.6 0.1 6.8 5.3 0.0 2.7 2 1 1 3 3 3 0 Nup133 N terminal like TLP-20 PF06088.11 EKX43821.1 - 0.7 9.8 6.7 3.8 7.4 0.6 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PAC1 PF16094.5 EKX43821.1 - 6.9 5.7 6.7 14 4.7 6.7 1.5 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 BSP_II PF05432.11 EKX43821.1 - 8.5 6.0 22.5 0.44 10.2 9.2 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Plectin PF00681.20 EKX43822.1 - 0.13 12.2 0.0 0.99 9.3 0.0 2.0 2 0 0 2 2 2 0 Plectin repeat PI3K_P85_iSH2 PF16454.5 EKX43823.1 - 0.001 18.7 12.8 0.001 18.7 12.8 3.5 3 1 1 4 4 4 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Daxx PF03344.15 EKX43823.1 - 0.12 12.5 6.8 0.39 10.8 0.1 2.9 2 1 0 3 3 3 0 Daxx N-terminal Rassf1C-interacting domain Mitovir_RNA_pol PF05919.11 EKX43823.1 - 0.55 9.3 4.8 0.34 10.0 2.3 1.7 1 1 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase DUF1515 PF07439.11 EKX43823.1 - 2.7 8.1 6.3 3.7 7.6 1.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) DUF1664 PF07889.12 EKX43823.1 - 4.2 7.4 13.2 15 5.6 1.0 3.8 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4079 PF13301.6 EKX43824.1 - 3.1e-44 150.6 0.0 4.7e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4079) HOOK PF05622.12 EKX43824.1 - 0.017 13.3 1.4 0.028 12.6 1.4 1.2 1 0 0 1 1 1 0 HOOK protein TEX13 PF15186.6 EKX43824.1 - 0.02 14.6 2.0 0.035 13.8 0.2 1.9 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family DUF5082 PF16888.5 EKX43824.1 - 0.021 15.1 0.1 0.036 14.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) LRRFIP PF09738.9 EKX43824.1 - 0.026 14.0 0.5 0.044 13.3 0.5 1.2 1 0 0 1 1 1 0 LRRFIP family DHR10 PF18595.1 EKX43824.1 - 0.03 14.4 3.2 0.03 14.4 3.2 1.6 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain HemX PF04375.14 EKX43824.1 - 0.12 11.6 0.3 0.19 11.0 0.0 1.4 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase SOGA PF11365.8 EKX43824.1 - 0.12 13.5 2.3 0.26 12.4 2.3 1.5 1 0 0 1 1 1 0 Protein SOGA Fzo_mitofusin PF04799.13 EKX43824.1 - 0.16 11.5 0.4 0.32 10.5 0.4 1.5 1 0 0 1 1 1 0 fzo-like conserved region DUF4140 PF13600.6 EKX43824.1 - 0.3 11.5 3.6 35 4.9 1.9 3.0 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Pil1 PF13805.6 EKX43824.1 - 0.31 10.5 2.2 0.55 9.7 2.2 1.3 1 0 0 1 1 1 0 Eisosome component PIL1 CLZ PF16526.5 EKX43824.1 - 0.35 11.3 6.0 0.93 9.9 1.2 2.7 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DivIC PF04977.15 EKX43824.1 - 0.41 10.4 4.5 1.4 8.7 0.1 2.8 2 1 1 3 3 3 0 Septum formation initiator CtIP_N PF10482.9 EKX43824.1 - 0.51 10.4 3.2 0.58 10.2 0.0 2.4 3 0 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain DUF3450 PF11932.8 EKX43824.1 - 0.67 9.2 3.6 0.31 10.3 1.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 EKX43824.1 - 0.78 10.3 6.6 1.2 9.6 6.6 1.4 1 1 0 1 1 1 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 EKX43824.1 - 1.7 8.9 8.2 0.46 10.7 4.7 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4164 PF13747.6 EKX43824.1 - 2.2 8.6 7.2 0.44 10.9 2.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) TPR_MLP1_2 PF07926.12 EKX43824.1 - 3.1 7.9 8.5 0.63 10.1 3.9 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Glyco_hydro_99 PF16317.5 EKX43826.1 - 2.1e-116 388.8 2.6 1.2e-115 386.4 2.6 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 99 Glyco_hydro_71 PF03659.14 EKX43826.1 - 9.7e-06 24.6 0.6 2.9e-05 23.1 0.6 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 71 Glyco_tran_WbsX PF14307.6 EKX43826.1 - 0.00057 19.4 0.3 0.0016 18.0 0.0 1.8 2 1 1 3 3 3 1 Glycosyltransferase WbsX DUF4434 PF14488.6 EKX43826.1 - 0.0012 18.9 0.5 0.0049 16.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4434) IGPS PF00218.21 EKX43827.1 - 5.1e-18 65.2 0.1 7.5e-18 64.6 0.1 1.2 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase ADH_zinc_N PF00107.26 EKX43827.1 - 0.0044 17.0 0.1 0.011 15.7 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DHO_dh PF01180.21 EKX43827.1 - 0.018 14.3 0.1 0.059 12.6 0.0 1.8 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase Methyltransf_25 PF13649.6 EKX43828.1 - 3.7e-07 30.8 0.0 7.8e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX43828.1 - 3.7e-06 26.8 0.0 4.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX43828.1 - 3.3e-05 24.4 0.1 6.6e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX43828.1 - 0.00016 22.3 0.1 0.00039 21.1 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 EKX43828.1 - 0.0015 19.6 0.0 0.0078 17.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EKX43828.1 - 0.002 17.7 0.1 0.0031 17.1 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 EKX43828.1 - 0.0094 15.9 0.1 0.023 14.6 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EKX43828.1 - 0.019 14.3 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 EKX43828.1 - 0.02 14.4 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase ANF_receptor PF01094.28 EKX43828.1 - 0.026 13.6 0.1 0.042 13.0 0.1 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region Methyltransf_23 PF13489.6 EKX43828.1 - 0.038 13.8 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EKX43828.1 - 0.038 13.7 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) tRNA_U5-meth_tr PF05958.11 EKX43828.1 - 0.083 11.9 0.2 0.15 11.0 0.2 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase PrmA PF06325.13 EKX43828.1 - 0.16 11.3 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RabGAP-TBC PF00566.18 EKX43831.1 - 1.1e-51 175.6 0.2 1.5e-51 175.1 0.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Xan_ur_permease PF00860.20 EKX43833.1 - 9.7e-63 212.2 19.9 5.1e-42 143.9 6.9 2.4 2 1 0 2 2 2 2 Permease family Nodulin_late PF07127.11 EKX43833.1 - 0.099 13.0 0.1 0.71 10.3 0.0 2.5 2 0 0 2 2 2 0 Late nodulin protein MFS_MOT1 PF16983.5 EKX43833.1 - 0.52 10.7 14.0 0.25 11.8 2.3 3.5 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily SET PF00856.28 EKX43834.1 - 0.0041 17.5 0.2 0.026 14.9 0.0 2.2 2 0 0 2 2 2 1 SET domain Myc_N PF01056.18 EKX43834.1 - 0.28 11.0 9.0 0.038 13.9 4.3 1.8 2 0 0 2 2 2 0 Myc amino-terminal region Leu_zip PF15294.6 EKX43836.1 - 0.0044 16.6 30.9 0.0097 15.4 9.5 2.6 1 1 1 2 2 2 1 Leucine zipper GIT_CC PF16559.5 EKX43836.1 - 0.011 15.5 0.4 0.011 15.5 0.4 4.3 3 2 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Csm1_N PF18504.1 EKX43836.1 - 0.026 14.9 5.3 0.026 14.9 5.3 5.3 3 2 2 5 5 5 0 Csm1 N-terminal domain HALZ PF02183.18 EKX43836.1 - 0.029 14.6 22.6 1.5 9.1 0.5 4.9 4 1 0 4 4 4 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 EKX43836.1 - 0.094 12.8 28.4 0.2 11.7 2.5 5.0 4 0 0 4 4 4 0 Basic region leucine zipper Pox_A_type_inc PF04508.12 EKX43836.1 - 0.21 11.5 20.0 0.86 9.6 0.0 5.5 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat ZapB PF06005.12 EKX43836.1 - 0.22 12.0 40.3 0.27 11.7 7.5 4.5 3 1 1 4 4 4 0 Cell division protein ZapB bZIP_1 PF00170.21 EKX43836.1 - 0.27 11.4 29.7 0.38 10.9 3.4 4.5 4 0 0 4 4 4 0 bZIP transcription factor ADIP PF11559.8 EKX43836.1 - 0.87 9.7 35.3 1.2 9.2 7.9 3.3 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF5320 PF17253.2 EKX43836.1 - 1.8 9.6 14.8 4.3 8.5 0.1 4.0 3 1 1 4 4 4 0 Family of unknown function (DUF5320) HAP1_N PF04849.13 EKX43836.1 - 2.9 7.0 42.4 5.8e+02 -0.5 42.8 2.1 1 1 0 1 1 1 0 HAP1 N-terminal conserved region CENP-F_leu_zip PF10473.9 EKX43836.1 - 3.2 7.8 40.6 0.2 11.7 6.9 3.9 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 XkdW PF09636.10 EKX43836.1 - 3.4 7.8 9.0 0.14 12.3 1.3 2.3 2 1 0 2 2 2 0 XkdW protein MbeD_MobD PF04899.12 EKX43836.1 - 3.8 7.7 17.6 12 6.1 0.1 5.0 3 2 2 5 5 5 0 MbeD/MobD like NPV_P10 PF05531.12 EKX43836.1 - 4.1 7.9 15.5 3.7 8.1 0.4 4.0 3 2 0 4 4 4 0 Nucleopolyhedrovirus P10 protein LPP PF04728.13 EKX43836.1 - 5.4 7.5 10.9 7 7.1 0.2 4.3 4 1 0 4 4 4 0 Lipoprotein leucine-zipper Maf1 PF09174.10 EKX43837.1 - 1.8e-46 158.5 1.5 2.4e-46 158.1 1.5 1.1 1 0 0 1 1 1 1 Maf1 regulator PB1 PF00564.24 EKX43837.1 - 0.16 11.9 1.6 0.2 11.6 0.4 1.7 2 0 0 2 2 2 0 PB1 domain Ank_2 PF12796.7 EKX43838.1 - 1.9e-18 66.8 0.2 7.4e-07 29.7 0.1 4.7 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX43838.1 - 6.6e-13 48.6 5.0 0.00062 20.0 0.0 7.3 7 2 0 7 7 7 3 Ankyrin repeats (many copies) BIR PF00653.21 EKX43838.1 - 4.4e-09 36.9 0.0 8.9e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain Ank_4 PF13637.6 EKX43838.1 - 5e-09 36.5 3.8 0.45 11.2 0.0 6.4 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX43838.1 - 1.8e-06 27.9 7.9 0.1 13.2 0.0 7.5 7 0 0 7 7 7 1 Ankyrin repeat Ank PF00023.30 EKX43838.1 - 3.3e-06 27.3 9.2 0.089 13.3 0.0 7.0 7 0 0 7 7 7 1 Ankyrin repeat zf-C3HC PF07967.13 EKX43838.1 - 0.093 12.8 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 C3HC zinc finger-like Receptor_2B4 PF11465.8 EKX43838.1 - 0.13 12.5 2.8 4.7 7.4 0.0 3.2 3 0 0 3 3 3 0 Natural killer cell receptor 2B4 DUF1598 PF07643.11 EKX43839.1 - 0.12 12.6 0.1 0.25 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1598) TPR_17 PF13431.6 EKX43840.1 - 8e-24 82.3 23.7 0.002 18.4 0.0 10.9 12 1 1 13 13 11 6 Tetratricopeptide repeat TPR_19 PF14559.6 EKX43840.1 - 6.4e-19 68.2 15.3 0.00037 21.0 0.1 8.9 7 2 1 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 EKX43840.1 - 1.2e-18 65.6 24.8 9.9e-05 22.2 0.1 12.2 13 0 0 13 13 12 5 Tetratricopeptide repeat TPR_14 PF13428.6 EKX43840.1 - 9.1e-18 63.4 15.6 0.00027 21.5 0.0 12.4 7 4 6 13 13 13 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX43840.1 - 1.9e-15 55.7 11.2 0.00021 21.3 0.1 10.6 13 0 0 13 13 13 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX43840.1 - 1.1e-11 44.2 10.8 0.022 14.4 0.1 9.3 11 1 1 12 12 12 2 TPR repeat TPR_1 PF00515.28 EKX43840.1 - 1.5e-10 40.4 22.0 0.0022 17.7 0.2 9.2 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX43840.1 - 6.7e-08 32.7 14.4 0.076 13.3 0.1 7.2 7 1 1 8 8 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX43840.1 - 1.3e-07 31.7 6.5 0.45 10.8 0.2 4.8 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EKX43840.1 - 4.4e-05 24.1 13.2 0.0024 18.5 0.3 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX43840.1 - 0.0074 16.3 14.4 0.41 10.8 0.0 7.3 6 2 1 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX43840.1 - 0.017 15.3 1.1 0.27 11.4 0.1 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX43840.1 - 0.45 11.3 10.8 76 4.3 0.0 7.3 8 0 0 8 8 7 0 Tetratricopeptide repeat UvrD-helicase PF00580.21 EKX43840.1 - 8.7 5.8 11.3 0.22 11.0 3.5 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Ldt_C PF17969.1 EKX43841.1 - 0.1 13.3 0.5 0.41 11.4 0.1 2.1 1 1 1 2 2 2 0 L,D-transpeptidase C-terminal domain PDDEXK_9 PF08011.11 EKX43841.1 - 0.39 10.6 3.4 0.15 12.0 0.7 1.7 2 1 0 2 2 2 0 PD-(D/E)XK nuclease superfamily DUF572 PF04502.13 EKX43841.1 - 4.6 6.8 11.1 5.4 6.5 11.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ank_4 PF13637.6 EKX43842.1 - 8e-25 86.9 0.4 1.7e-11 44.4 0.1 3.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX43842.1 - 5.3e-20 71.8 0.0 4.7e-12 46.3 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX43842.1 - 3.2e-18 63.9 0.4 3.4e-05 23.9 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EKX43842.1 - 8.5e-17 61.0 0.6 1.7e-07 31.4 0.2 2.6 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX43842.1 - 1.5e-16 60.0 1.4 0.00033 21.0 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat EPSP_synthase PF00275.20 EKX43842.1 - 0.074 11.7 0.0 5.4 5.6 0.0 2.0 1 1 1 2 2 2 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Aa_trans PF01490.18 EKX43843.1 - 4.1e-14 52.1 7.3 4.1e-14 52.1 7.3 3.3 3 1 1 4 4 4 2 Transmembrane amino acid transporter protein Cyclin_N PF00134.23 EKX43844.1 - 1.3e-09 37.9 0.0 1.3e-08 34.7 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EKX43844.1 - 0.063 13.4 0.0 1.3 9.2 0.0 2.1 2 0 0 2 2 2 0 Cyclin, C-terminal domain MCD_N PF17408.2 EKX43844.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain Beach PF02138.18 EKX43845.1 - 1.7e-119 398.3 0.3 2.1e-119 398.0 0.3 1.1 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 EKX43845.1 - 4.7e-09 36.3 0.1 1.1e-08 35.1 0.1 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH GGDEF PF00990.21 EKX43846.1 - 0.047 13.4 0.0 0.054 13.2 0.0 1.0 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain Methyltransf_16 PF10294.9 EKX43847.1 - 1.4e-16 60.8 0.0 2.1e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EKX43847.1 - 9.3e-05 22.0 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EKX43847.1 - 0.00047 20.8 0.0 0.00099 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 EKX43847.1 - 0.0078 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_31 PF13847.6 EKX43847.1 - 0.2 11.4 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ephrin_rec_like PF07699.13 EKX43848.1 - 0.012 15.3 11.2 0.012 15.3 11.2 3.0 2 1 1 3 3 3 0 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX43848.1 - 0.13 12.7 12.2 0.25 11.8 2.0 2.9 1 1 1 2 2 2 0 TNFR/NGFR cysteine-rich region Opy2 PF09463.10 EKX43848.1 - 0.4 11.0 16.2 0.56 10.6 4.2 3.5 4 0 0 4 4 4 0 Opy2 protein Lustrin_cystein PF14625.6 EKX43848.1 - 2.8 8.4 22.5 6.6 7.2 0.5 3.5 1 1 0 2 2 2 0 Lustrin, cysteine-rich repeated domain Granulin PF00396.18 EKX43848.1 - 7.8 6.9 12.9 20 5.6 0.1 3.9 4 1 0 4 4 4 0 Granulin WD40 PF00400.32 EKX43849.1 - 2.7e-20 72.3 38.6 0.00074 20.3 0.2 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX43849.1 - 9e-15 54.8 11.7 0.01 16.1 0.6 5.8 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EKX43849.1 - 3.4e-14 52.3 31.2 0.12 12.3 0.8 7.5 7 0 0 7 7 7 6 WD40-like Beta Propeller Repeat eIF2A PF08662.11 EKX43849.1 - 9.9e-13 48.4 0.1 9.2e-05 22.4 0.0 3.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 EKX43849.1 - 7.3e-07 28.8 2.8 1.1 8.5 0.0 5.6 2 2 4 6 6 6 2 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.12 EKX43849.1 - 7.3e-07 27.6 18.9 0.0025 15.9 3.2 3.2 1 1 1 3 3 3 3 IKI3 family DPPIV_N PF00930.21 EKX43849.1 - 7.8e-07 28.2 8.0 0.3 9.8 0.0 6.3 3 3 3 6 6 6 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Proteasome_A_N PF10584.9 EKX43849.1 - 0.0047 16.6 14.5 41 4.0 0.1 6.6 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature PGM_PMM_IV PF00408.20 EKX43849.1 - 0.016 15.3 0.4 9.9 6.4 0.0 3.0 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain eIF-1a PF01176.19 EKX43849.1 - 0.039 13.8 0.0 70 3.3 0.0 4.4 4 2 1 5 5 5 0 Translation initiation factor 1A / IF-1 DUF333 PF03891.15 EKX43849.1 - 0.067 13.4 1.1 67 3.8 0.0 4.8 5 0 0 5 5 5 0 Domain of unknown function (DUF333) Nup160 PF11715.8 EKX43849.1 - 0.21 10.2 1.6 19 3.7 0.1 3.2 3 1 1 4 4 4 0 Nucleoporin Nup120/160 Nab2p_Zf1 PF18260.1 EKX43849.1 - 2.6 8.0 12.0 2.3e+02 1.8 0.1 6.4 7 0 0 7 7 7 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 NACHT PF05729.12 EKX43850.1 - 4.6e-05 23.4 0.0 0.00011 22.2 0.0 1.7 1 1 0 1 1 1 1 NACHT domain Sif PF06767.11 EKX43850.1 - 0.0099 14.9 0.3 0.016 14.2 0.3 1.2 1 0 0 1 1 1 1 Sif protein AAA_29 PF13555.6 EKX43850.1 - 0.013 15.3 0.1 0.026 14.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 EKX43850.1 - 0.021 14.6 0.0 0.046 13.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 EKX43850.1 - 0.026 13.7 0.0 0.059 12.5 0.0 1.4 1 1 0 1 1 1 0 G-protein alpha subunit NB-ARC PF00931.22 EKX43850.1 - 0.03 13.5 0.5 0.59 9.3 0.4 2.3 1 1 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 EKX43850.1 - 0.059 12.6 0.1 0.2 10.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_PrkA PF08298.11 EKX43850.1 - 0.085 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain AAA_25 PF13481.6 EKX43850.1 - 0.1 12.2 0.1 0.19 11.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 EKX43850.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 EKX43850.1 - 0.12 12.8 0.0 0.23 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EKX43850.1 - 0.12 12.7 0.0 0.53 10.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EKX43850.1 - 0.18 11.1 0.0 0.38 10.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Laminin_G_3 PF13385.6 EKX43852.1 - 2.6e-13 50.4 1.4 2.6e-13 50.4 1.4 2.7 4 0 0 4 4 4 1 Concanavalin A-like lectin/glucanases superfamily Ephrin_rec_like PF07699.13 EKX43852.1 - 3.1e-11 42.8 20.4 5.1e-07 29.4 3.0 3.9 2 1 2 4 4 4 3 Putative ephrin-receptor like RANK_CRD_2 PF18278.1 EKX43852.1 - 0.76 10.0 8.1 4.9 7.4 0.8 3.0 2 1 1 3 3 3 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 RCC1 PF00415.18 EKX43856.1 - 2.6e-47 159.2 4.5 5.4e-10 39.7 0.0 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX43856.1 - 1.8e-26 91.3 25.6 7.4e-09 35.2 0.0 5.7 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat C2 PF00168.30 EKX43856.1 - 2.5e-17 63.0 0.0 1.5e-16 60.5 0.0 2.0 1 1 0 1 1 1 1 C2 domain MRP-L28 PF09812.9 EKX43856.1 - 0.46 10.6 5.4 0.75 9.9 5.4 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 C2 PF00168.30 EKX43857.1 - 9.4e-38 128.7 0.1 1.1e-16 60.9 0.1 4.3 4 0 0 4 4 4 3 C2 domain PAPS_reduct PF01507.19 EKX43858.1 - 2.4e-36 125.4 0.0 3e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ATP-synt_ab_N PF02874.23 EKX43860.1 - 0.089 13.3 0.0 0.31 11.6 0.0 1.9 1 0 0 1 1 1 0 ATP synthase alpha/beta family, beta-barrel domain DUF2315 PF10231.9 EKX43860.1 - 1 9.5 6.1 0.22 11.7 0.4 2.8 3 0 0 3 3 3 0 Apoptogenic protein 1 Ank_2 PF12796.7 EKX43861.1 - 1.6e-12 47.8 0.0 2.6e-11 43.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX43861.1 - 2.3e-12 46.0 0.8 0.00044 20.5 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EKX43861.1 - 7.3e-12 45.6 0.1 9.8e-07 29.2 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX43861.1 - 4.5e-11 42.7 1.8 0.011 16.2 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EKX43861.1 - 3e-10 40.2 0.2 5.3e-07 29.8 0.0 3.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) TRM PF02005.16 EKX43861.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Ank_5 PF13857.6 EKX43862.1 - 7.8e-15 54.8 0.1 2e-07 31.2 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeats (many copies) RRM_1 PF00076.22 EKX43862.1 - 3.7e-13 49.1 0.0 4.7e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ank_2 PF12796.7 EKX43862.1 - 1.1e-12 48.4 0.0 5.7e-07 30.0 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EKX43862.1 - 3.3e-11 43.1 0.0 0.011 16.2 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EKX43862.1 - 3.1e-10 39.4 0.2 0.0013 19.0 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EKX43862.1 - 3.3e-09 37.1 0.1 0.0058 17.2 0.0 4.0 3 2 1 4 4 4 2 Ankyrin repeats (many copies) PHM7_cyt PF14703.6 EKX43862.1 - 0.044 14.0 0.0 0.87 9.8 0.0 2.2 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter 2-Hacid_dh_C PF02826.19 EKX43863.1 - 0.0001 21.7 0.0 0.00022 20.7 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 EKX43863.1 - 0.035 13.7 0.1 0.065 12.9 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 EKX43863.1 - 0.042 14.0 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase HipA_C PF07804.12 EKX43863.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 HipA-like C-terminal domain TrkA_N PF02254.18 EKX43863.1 - 0.1 12.8 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 EKX43863.1 - 0.2 11.7 0.0 0.35 10.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ion_trans PF00520.31 EKX43864.1 - 2.2e-28 99.2 24.3 7.6e-28 97.4 24.3 1.8 1 1 0 1 1 1 1 Ion transport protein PH PF00169.29 EKX43864.1 - 0.15 12.5 0.0 0.31 11.6 0.0 1.5 1 0 0 1 1 1 0 PH domain Laminin_G_3 PF13385.6 EKX43866.1 - 7.2e-05 23.0 0.0 0.0011 19.2 0.0 2.4 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Proteasom_PSMB PF10508.9 EKX43866.1 - 0.0094 14.5 0.0 0.031 12.8 0.0 1.8 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit DUF1216 PF06746.11 EKX43866.1 - 0.02 14.9 0.6 0.069 13.2 0.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) MRC1 PF09444.10 EKX43866.1 - 0.82 10.2 9.2 2.8 8.5 9.2 1.9 1 0 0 1 1 1 0 MRC1-like domain Herpes_pp85 PF04637.12 EKX43866.1 - 0.88 7.9 3.8 1.6 7.0 3.8 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Filament PF00038.21 EKX43867.1 - 0.02 14.5 11.8 0.12 11.9 11.8 2.0 1 1 0 1 1 1 0 Intermediate filament protein CLZ PF16526.5 EKX43867.1 - 0.031 14.6 7.9 0.18 12.2 2.4 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc7 PF08317.11 EKX43867.1 - 0.068 12.0 8.6 0.096 11.5 8.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 EKX43867.1 - 0.22 10.9 1.8 0.24 10.7 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 EKX43867.1 - 0.32 11.4 12.1 0.52 10.7 12.1 1.3 1 1 0 1 1 1 0 Fez1 Mt_ATP-synt_B PF05405.14 EKX43867.1 - 0.37 10.4 3.9 0.6 9.7 3.9 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) zf-C4H2 PF10146.9 EKX43867.1 - 0.4 10.9 5.3 0.52 10.6 5.3 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein V_ATPase_I PF01496.19 EKX43867.1 - 0.56 8.1 3.6 0.57 8.0 3.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nas2_N PF18265.1 EKX43867.1 - 1.2 9.1 9.1 2.8 7.9 1.2 3.2 2 1 1 3 3 3 0 Nas2 N_terminal domain COG2 PF06148.11 EKX43867.1 - 1.7 8.7 6.7 11 6.2 1.4 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FlxA PF14282.6 EKX43867.1 - 3.3 7.8 8.8 0.37 10.8 4.0 1.9 2 0 0 2 2 2 0 FlxA-like protein PNRC PF15365.6 EKX43868.1 - 5.7e-06 26.0 6.5 5.7e-06 26.0 6.5 3.2 4 0 0 4 4 4 1 Proline-rich nuclear receptor coactivator motif HAD_2 PF13419.6 EKX43869.1 - 5.1e-31 108.1 0.0 5.9e-31 107.9 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EKX43869.1 - 8.3e-12 45.8 0.0 2.4e-10 41.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EKX43869.1 - 9.6e-05 22.9 0.0 0.00014 22.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EKX43869.1 - 0.00086 19.3 0.0 0.0037 17.3 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like TERF2_RBM PF16772.5 EKX43869.1 - 0.057 12.9 0.2 0.15 11.5 0.2 1.7 1 0 0 1 1 1 0 Telomeric repeat-binding factor 2 Rap1-binding motif ERCC4 PF02732.15 EKX43870.1 - 3.2e-18 66.4 2.2 3.3e-18 66.4 0.2 2.1 3 0 0 3 3 3 1 ERCC4 domain HHH PF00633.23 EKX43870.1 - 0.069 13.1 0.3 0.9 9.5 0.1 2.9 3 0 0 3 3 3 0 Helix-hairpin-helix motif Sulfate_transp PF00916.20 EKX43871.1 - 4.8e-107 358.0 19.7 6.8e-107 357.5 19.7 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EKX43871.1 - 8e-10 38.4 0.0 1.4e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EKX43871.1 - 3.8e-06 27.3 4.4 3.8e-06 27.3 4.4 4.0 4 0 0 4 4 4 1 Molybdate transporter of MFS superfamily fn2 PF00040.19 EKX43873.1 - 1.8e-08 34.5 25.9 2.1e-06 27.9 1.9 3.2 3 0 0 3 3 3 2 Fibronectin type II domain Serine_rich PF08824.10 EKX43875.1 - 0.009 16.0 0.3 0.011 15.8 0.3 1.1 1 0 0 1 1 1 1 Serine rich protein interaction domain Ank PF00023.30 EKX43877.1 - 1.4e-14 53.7 0.7 7.4e-07 29.3 0.2 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EKX43877.1 - 3.9e-11 43.4 0.1 0.00011 22.7 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX43877.1 - 1.4e-10 41.5 0.4 1.2e-07 32.2 0.3 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX43877.1 - 2.4e-09 37.3 0.4 4.4e-07 30.1 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX43877.1 - 1.2e-07 31.5 0.1 0.0063 16.9 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat Methyltransf_32 PF13679.6 EKX43878.1 - 0.0011 19.0 0.0 0.007 16.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain DUF3915 PF13054.6 EKX43878.1 - 3.4 7.6 6.5 14 5.6 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Acyl-CoA_dh_1 PF00441.24 EKX43879.1 - 3.5e-32 111.7 4.1 4.8e-32 111.3 4.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EKX43879.1 - 1.5e-20 73.1 0.0 2.7e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EKX43879.1 - 9.4e-11 42.4 0.0 1.9e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EKX43879.1 - 1.6e-08 34.9 3.3 2.5e-08 34.3 3.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyclin PF08613.11 EKX43880.1 - 1e-29 104.0 0.0 1.3e-29 103.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EKX43880.1 - 8e-05 22.4 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Radical_SAM_C PF16199.5 EKX43882.1 - 1.2e-13 50.8 0.2 2.5e-13 49.8 0.2 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EKX43882.1 - 1.8e-13 51.2 2.4 7.6e-13 49.2 2.4 2.0 1 1 0 1 1 1 1 Radical SAM superfamily Acetyltransf_10 PF13673.7 EKX43882.1 - 0.0056 16.6 0.3 0.015 15.2 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EKX43882.1 - 0.011 16.0 0.1 0.043 14.1 0.1 2.1 2 1 0 2 2 2 0 Acetyltransferase (GNAT) family Lipase_3 PF01764.25 EKX43883.1 - 8.8e-27 93.7 0.0 4.1e-25 88.3 0.0 2.4 2 0 0 2 2 2 1 Lipase (class 3) C2 PF00168.30 EKX43883.1 - 1.1e-06 28.8 0.0 0.0028 17.9 0.0 2.9 2 0 0 2 2 2 2 C2 domain IMUP PF15761.5 EKX43883.1 - 0.018 15.7 5.0 0.06 14.0 5.0 1.9 1 0 0 1 1 1 0 Immortalisation up-regulated protein PGAP1 PF07819.13 EKX43883.1 - 0.032 13.9 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 EKX43883.1 - 0.17 12.5 0.4 0.48 11.0 0.1 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF3446 PF11928.8 EKX43883.1 - 1.2 9.5 16.5 0.24 11.8 9.7 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain SR-25 PF10500.9 EKX43883.1 - 4 7.0 15.6 13 5.3 15.3 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ribosomal_S19e PF01090.19 EKX43884.1 - 8.1e-54 181.0 0.0 9.3e-54 180.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HxlR PF01638.17 EKX43884.1 - 0.034 14.0 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 HxlR-like helix-turn-helix Ribosomal_S19e PF01090.19 EKX43885.1 - 6.5e-54 181.3 0.0 7.4e-54 181.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HxlR PF01638.17 EKX43885.1 - 0.031 14.1 0.0 0.047 13.5 0.0 1.3 1 0 0 1 1 1 0 HxlR-like helix-turn-helix REJ PF02010.15 EKX43886.1 - 5.6e-41 140.8 4.4 5.6e-41 140.8 4.4 3.3 3 1 1 4 4 4 2 REJ domain TNFR_c6 PF00020.18 EKX43886.1 - 6.2e-11 42.5 85.4 0.00095 19.5 10.7 7.8 5 1 2 7 7 7 5 TNFR/NGFR cysteine-rich region Guanylate_cyc PF00211.20 EKX43887.1 - 9.7e-25 87.2 0.0 1.1e-24 87.1 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain RhoGEF67_u2 PF16614.5 EKX43887.1 - 0.13 12.3 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Unstructured region two on RhoGEF 6 and 7 Guanylate_cyc PF00211.20 EKX43888.1 - 5.8e-23 81.4 0.2 6.4e-23 81.3 0.2 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain ComFB PF10719.9 EKX43888.1 - 0.17 12.0 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Late competence development protein ComFB Shugoshin_N PF07558.11 EKX43889.1 - 2 8.4 17.9 1.7 8.6 2.5 4.3 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region TPR_MLP1_2 PF07926.12 EKX43889.1 - 8.3 6.5 94.0 0.093 12.8 16.7 5.9 5 2 2 7 7 7 0 TPR/MLP1/MLP2-like protein Bac_surface_Ag PF01103.23 EKX43890.1 - 5.4e-32 111.6 0.4 6.9e-32 111.2 0.4 1.1 1 0 0 1 1 1 1 Surface antigen UPF0164 PF03687.13 EKX43890.1 - 0.002 17.0 0.1 0.0033 16.3 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0164) POTRA PF07244.15 EKX43890.1 - 0.021 15.4 0.0 0.033 14.7 0.0 1.4 1 0 0 1 1 1 0 Surface antigen variable number repeat REJ PF02010.15 EKX43891.1 - 1.8e-41 142.4 4.7 1.8e-41 142.4 4.7 3.2 3 1 1 4 4 4 2 REJ domain TNFR_c6 PF00020.18 EKX43891.1 - 3.5e-09 36.9 152.2 0.00068 20.0 4.6 12.8 9 2 3 12 12 12 9 TNFR/NGFR cysteine-rich region EGF_2 PF07974.13 EKX43892.1 - 1.5e-09 38.1 201.3 0.00045 20.5 16.6 10.8 7 5 5 12 12 12 6 EGF-like domain DSL PF01414.19 EKX43892.1 - 1.9e-07 31.2 136.1 0.27 11.5 16.1 6.3 6 0 0 6 6 6 6 Delta serrate ligand Laminin_EGF PF00053.24 EKX43892.1 - 0.041 14.0 141.2 0.88 9.8 13.8 10.9 1 1 9 12 12 12 0 Laminin EGF domain EGF PF00008.27 EKX43892.1 - 1.5 9.1 140.2 0.22 11.9 11.1 9.0 12 0 0 12 12 12 0 EGF-like domain AAA_lid_3 PF17862.1 EKX43892.1 - 2 8.3 10.5 1.7e+02 2.1 0.1 5.2 5 0 0 5 5 5 0 AAA+ lid domain Thioredoxin_8 PF13905.6 EKX43894.1 - 6.1e-28 97.0 0.0 7.8e-28 96.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 EKX43894.1 - 4.8e-08 32.9 0.0 5.8e-07 29.5 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 EKX43894.1 - 5.7e-05 23.5 0.0 8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 EKX43894.1 - 0.00015 21.6 0.0 0.00016 21.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 EKX43894.1 - 0.0015 18.3 0.0 0.0057 16.4 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.6 EKX43894.1 - 0.0038 17.4 0.0 0.0061 16.7 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 EKX43894.1 - 0.0094 15.7 0.0 0.0094 15.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin Glutaredoxin PF00462.24 EKX43894.1 - 0.019 15.2 0.0 0.057 13.7 0.0 1.9 1 1 0 1 1 1 0 Glutaredoxin NADH_4Fe-4S PF10589.9 EKX43894.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Rad4 PF03835.15 EKX43895.1 - 3.3e-14 52.8 2.6 5e-14 52.2 2.6 1.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 EKX43895.1 - 2.1e-11 44.2 0.5 4e-11 43.3 0.5 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily PAW PF04721.17 EKX43895.1 - 0.0069 16.2 1.6 0.011 15.6 1.6 1.3 1 0 0 1 1 1 1 PNGase C-terminal domain, mannose-binding module PAW Lar_restr_allev PF14354.6 EKX43895.1 - 0.035 14.5 6.7 0.6 10.5 6.7 2.5 1 1 0 1 1 1 0 Restriction alleviation protein Lar AdoHcyase PF05221.17 EKX43896.1 - 4.4e-143 475.8 0.0 5e-143 475.7 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EKX43896.1 - 6e-80 267.0 4.5 8.6e-80 266.5 4.5 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EKX43896.1 - 2.1e-07 30.5 0.3 3.7e-07 29.7 0.3 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EKX43896.1 - 0.0039 16.8 0.2 0.0067 16.0 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain THF_DHG_CYH_C PF02882.19 EKX43896.1 - 0.011 15.1 1.2 0.034 13.5 1.2 1.7 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TrkA_N PF02254.18 EKX43896.1 - 0.059 13.6 0.1 0.32 11.3 0.1 2.3 2 1 0 2 2 2 0 TrkA-N domain Shikimate_DH PF01488.20 EKX43896.1 - 0.094 12.8 0.3 0.24 11.5 0.3 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Urocanase PF01175.18 EKX43896.1 - 0.11 12.2 0.2 0.2 11.3 0.2 1.4 1 0 0 1 1 1 0 Urocanase Rossmann-like domain CIA30 PF08547.12 EKX43897.1 - 3.3e-31 108.5 0.0 4e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) PCC_BT PF18140.1 EKX43897.1 - 0.04 14.2 0.0 0.064 13.6 0.0 1.2 1 0 0 1 1 1 0 Propionyl-coenzyme A carboxylase BT domain Lustrin_cystein PF14625.6 EKX43898.1 - 7.2 7.1 6.2 0.44 10.9 0.6 1.9 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain DnaJ PF00226.31 EKX43899.1 - 2.8e-24 85.0 3.8 4.7e-24 84.3 3.8 1.4 1 0 0 1 1 1 1 DnaJ domain OAD_gamma PF04277.13 EKX43899.1 - 0.038 14.6 0.1 0.056 14.0 0.1 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain GRP PF07172.11 EKX43899.1 - 0.53 11.0 3.3 1 10.1 0.1 2.3 2 1 0 2 2 2 0 Glycine rich protein family RWP-RK PF02042.15 EKX43900.1 - 5.7e-16 58.2 0.1 9.3e-16 57.5 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX43900.1 - 0.12 12.2 0.3 8.6 6.2 0.0 2.4 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family Svs_4_5_6 PF17381.2 EKX43900.1 - 0.6 11.1 8.4 0.54 11.3 1.7 2.8 1 1 2 3 3 3 0 Seminal vesicle secretory proteins 4/5/6 DUF4378 PF14309.6 EKX43901.1 - 0.071 13.5 0.0 2.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4378) EF-hand_1 PF00036.32 EKX43902.1 - 9.8e-21 71.7 7.4 4e-06 26.0 1.7 4.2 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 EKX43902.1 - 1.4e-18 67.1 3.5 1.5e-11 44.6 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX43902.1 - 5.8e-17 60.1 5.2 4e-07 29.4 0.0 4.5 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 EKX43902.1 - 3.1e-16 58.9 5.1 3.3e-08 33.3 0.1 3.4 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EKX43902.1 - 3e-14 51.8 7.4 7.2e-05 22.1 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 EKX43902.1 - 2.6e-07 30.8 0.1 7.7e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EKX43902.1 - 0.0097 15.8 1.5 0.61 10.1 0.1 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand FGAR-AT_linker PF18072.1 EKX43902.1 - 0.011 16.3 0.0 0.057 14.0 0.0 2.2 2 1 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain EF-hand_11 PF08976.11 EKX43902.1 - 0.011 16.6 0.1 0.31 11.9 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain UPF0154 PF03672.13 EKX43902.1 - 0.059 13.4 0.0 0.095 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Kelch_1 PF01344.25 EKX43903.1 - 3.6e-69 228.1 15.5 8.3e-15 54.1 0.1 6.8 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 EKX43903.1 - 1.9e-42 142.2 0.6 1e-08 35.1 0.0 6.5 2 2 4 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EKX43903.1 - 7.8e-31 105.8 0.1 7.9e-06 25.8 0.0 5.7 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_2 PF07646.15 EKX43903.1 - 5.6e-24 83.2 3.5 6.6e-05 22.7 0.0 7.3 7 0 0 7 7 7 5 Kelch motif BTB PF00651.31 EKX43903.1 - 2.9e-23 82.2 0.0 5.3e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_3 PF13415.6 EKX43903.1 - 7e-21 74.0 5.4 0.0015 18.8 0.2 6.8 6 0 0 6 6 6 6 Galactose oxidase, central domain BACK PF07707.15 EKX43903.1 - 6.8e-15 55.0 0.5 1.3e-14 54.1 0.5 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 EKX43903.1 - 9.3e-10 38.3 2.0 0.37 10.8 0.0 5.2 5 0 0 5 5 5 3 Kelch motif Dsl1_C PF11989.8 EKX43903.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 C terminal TPR_19 PF14559.6 EKX43904.1 - 2.6e-50 168.8 42.2 4.5e-06 27.1 0.3 17.4 12 5 5 18 18 18 12 Tetratricopeptide repeat TPR_2 PF07719.17 EKX43904.1 - 1.9e-37 124.3 60.6 0.00018 21.4 0.0 19.6 19 0 0 19 19 18 11 Tetratricopeptide repeat TPR_14 PF13428.6 EKX43904.1 - 3.3e-34 114.6 30.3 2.2e-05 24.9 0.0 19.2 16 3 5 21 21 20 7 Tetratricopeptide repeat TPR_16 PF13432.6 EKX43904.1 - 9.9e-27 93.3 19.5 0.0024 18.5 0.0 14.2 16 0 0 16 16 16 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX43904.1 - 1.6e-20 73.1 42.2 2.6e-05 24.4 0.8 14.2 9 4 3 13 13 13 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EKX43904.1 - 4.2e-20 70.7 58.3 0.011 15.5 0.1 16.0 17 0 0 17 17 17 6 Tetratricopeptide repeat TPR_7 PF13176.6 EKX43904.1 - 4.5e-19 67.0 23.8 0.15 12.2 0.0 14.1 14 0 0 14 14 14 5 Tetratricopeptide repeat TPR_12 PF13424.6 EKX43904.1 - 8.1e-18 64.5 45.0 0.086 13.1 1.5 13.5 11 3 4 15 15 14 7 Tetratricopeptide repeat TPR_8 PF13181.6 EKX43904.1 - 5.5e-13 48.0 54.3 0.0052 16.9 0.3 16.0 17 0 0 17 17 16 5 Tetratricopeptide repeat TPR_17 PF13431.6 EKX43904.1 - 1.8e-09 37.3 23.2 0.063 13.7 0.0 12.3 13 0 0 13 13 10 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX43904.1 - 8.2e-08 31.8 24.6 0.091 12.5 0.0 10.6 12 0 0 12 12 11 3 TPR repeat TPR_9 PF13371.6 EKX43904.1 - 1e-07 32.0 6.6 0.44 10.7 0.0 7.4 7 0 0 7 7 6 2 Tetratricopeptide repeat NARP1 PF12569.8 EKX43904.1 - 1.4e-06 27.6 32.7 0.047 12.6 0.0 8.2 5 3 3 9 9 9 5 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.6 EKX43904.1 - 1.9e-06 27.9 19.0 0.15 12.1 0.0 8.5 9 1 1 10 10 8 3 Fis1 C-terminal tetratricopeptide repeat HrpB1_HrpK PF09613.10 EKX43904.1 - 2e-06 27.5 13.1 1.2 8.8 0.0 9.1 9 3 0 9 9 9 2 Bacterial type III secretion protein (HrpB1_HrpK) TPR_4 PF07721.14 EKX43904.1 - 8.3e-05 22.8 3.2 34 5.5 0.2 7.7 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX43904.1 - 0.00011 22.5 44.4 0.061 14.0 0.0 16.1 18 0 0 18 18 17 1 Tetratricopeptide repeat FeoB_Cyto PF17910.1 EKX43904.1 - 0.024 15.2 3.8 0.037 14.6 1.0 3.1 2 0 0 2 2 1 0 FeoB cytosolic helical domain TPR_10 PF13374.6 EKX43904.1 - 0.031 14.2 16.4 23 5.0 0.0 10.0 11 0 0 11 11 11 0 Tetratricopeptide repeat Gag_p10 PF02337.17 EKX43904.1 - 0.079 12.9 0.0 0.3 11.0 0.0 2.0 1 0 0 1 1 1 0 Retroviral GAG p10 protein TPR_20 PF14561.6 EKX43904.1 - 0.13 12.7 25.6 2.3 8.6 0.1 9.1 9 2 2 11 11 10 0 Tetratricopeptide repeat PknG_TPR PF16918.5 EKX43904.1 - 1.9 7.1 9.1 11 4.6 0.0 5.3 5 2 1 7 7 7 0 Protein kinase G tetratricopeptide repeat TMF_DNA_bd PF12329.8 EKX43905.1 - 3 7.9 18.2 6.6 6.8 0.7 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Cys_rich_KTR PF14205.6 EKX43907.1 - 3.5e-05 23.5 24.0 2.4 8.0 0.7 8.7 9 0 0 9 9 9 4 Cysteine-rich KTR DUF1196 PF06709.11 EKX43907.1 - 0.003 17.7 3.1 5.2 7.3 0.0 5.7 6 1 1 7 7 7 1 Protein of unknown function (DUF1196) CTD PF12815.7 EKX43907.1 - 0.0069 16.9 0.0 0.64 10.6 0.0 2.8 2 1 0 2 2 2 1 Spt5 C-terminal nonapeptide repeat binding Spt4 RNase_T PF00929.24 EKX43908.1 - 6.8e-10 39.7 0.0 8.6e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 EKX43908.1 - 0.044 13.8 0.1 0.089 12.8 0.0 1.6 2 0 0 2 2 2 0 3' exoribonuclease, RNase T-like ParBc PF02195.18 EKX43909.1 - 2.3e-20 72.7 0.1 4.8e-20 71.7 0.1 1.6 1 0 0 1 1 1 1 ParB-like nuclease domain SoPB_HTH PF18090.1 EKX43909.1 - 0.0006 19.9 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Centromere-binding protein HTH domain WSN PF02206.18 EKX43909.1 - 0.00078 19.3 0.7 0.0071 16.2 0.2 2.9 1 1 1 2 2 2 1 Domain of unknown function DUF262 PF03235.14 EKX43909.1 - 0.03 14.5 6.2 0.057 13.6 6.0 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF262 Rho_N PF07498.12 EKX43910.1 - 0.1 12.5 0.1 0.28 11.1 0.1 1.7 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain P63C PF10546.9 EKX43911.1 - 0.1 13.2 1.1 0.64 10.6 0.1 2.3 2 1 0 2 2 2 0 P63C domain Ifi-6-16 PF06140.13 EKX43913.1 - 2.6e-15 56.1 40.0 2.6e-15 56.1 40.0 1.9 1 1 1 2 2 2 1 Interferon-induced 6-16 family CD20 PF04103.15 EKX43913.1 - 0.019 15.1 4.6 0.026 14.6 4.6 1.2 1 0 0 1 1 1 0 CD20-like family DUF4889 PF16230.5 EKX43913.1 - 0.16 12.2 0.1 0.27 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4889) Amidase_2 PF01510.25 EKX43916.1 - 1.2e-05 25.8 0.0 2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 N-acetylmuramoyl-L-alanine amidase Histone PF00125.24 EKX43916.1 - 0.012 15.9 2.8 0.62 10.4 0.2 2.5 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EKX43916.1 - 0.071 13.4 0.5 0.071 13.4 0.5 2.1 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RCC1_2 PF13540.6 EKX43917.1 - 2.3e-15 55.9 33.1 1.8e-06 27.6 4.7 6.4 5 2 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat DnaJ PF00226.31 EKX43918.1 - 2.5e-08 33.9 0.1 2.5e-08 33.9 0.1 1.8 2 0 0 2 2 2 1 DnaJ domain DUF2390 PF09523.10 EKX43918.1 - 0.14 12.5 4.3 0.37 11.2 3.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2390) Pex26 PF07163.12 EKX43919.1 - 0.012 15.0 0.3 1.7 7.9 0.5 2.0 2 0 0 2 2 2 0 Pex26 protein Ofd1_CTDD PF10637.9 EKX43919.1 - 0.098 12.0 0.2 0.14 11.5 0.2 1.3 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term AAA_6 PF12774.7 EKX43920.1 - 2.4e-155 516.5 0.0 1.2e-154 514.1 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EKX43920.1 - 7.3e-127 423.8 5.2 7.3e-127 423.8 5.2 3.3 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EKX43920.1 - 1.3e-106 355.7 0.0 5.1e-106 353.8 0.0 2.1 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EKX43920.1 - 1.2e-104 349.9 2.0 2.6e-104 348.8 0.0 2.7 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EKX43920.1 - 7.1e-88 293.4 0.6 4.4e-87 290.8 0.6 2.6 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 EKX43920.1 - 1e-77 259.8 0.0 9.1e-76 253.4 0.0 3.4 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EKX43920.1 - 3.8e-52 176.4 0.1 4.8e-51 172.8 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EKX43920.1 - 1.4e-42 144.5 0.0 3.5e-39 133.6 0.0 3.1 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain MT PF12777.7 EKX43920.1 - 4.8e-42 144.2 8.9 4.8e-42 144.2 8.9 2.4 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 EKX43920.1 - 4.4e-34 117.3 0.2 3.1e-33 114.6 0.1 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EKX43920.1 - 3.9e-18 65.8 0.0 3e-06 27.3 0.0 5.6 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 EKX43920.1 - 1.9e-14 53.7 2.4 1.9e-14 53.6 0.2 2.2 2 0 0 2 2 1 1 AAA+ lid domain AAA PF00004.29 EKX43920.1 - 5.3e-06 26.9 0.3 0.14 12.5 0.0 4.2 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EKX43920.1 - 0.00031 21.0 0.5 17 5.6 0.0 5.7 6 0 0 6 6 6 0 AAA domain RNA_helicase PF00910.22 EKX43920.1 - 0.02 15.3 0.1 9.3 6.7 0.0 3.9 3 0 0 3 3 3 0 RNA helicase AAA_30 PF13604.6 EKX43920.1 - 0.036 13.8 0.1 4.4 7.0 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EKX43920.1 - 0.047 14.1 0.3 29 5.0 0.0 4.1 3 0 0 3 3 3 0 AAA ATPase domain T2SSE PF00437.20 EKX43920.1 - 0.063 12.3 0.2 0.23 10.5 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.6 EKX43920.1 - 0.1 13.2 0.5 0.66 10.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EKX43920.1 - 0.18 11.9 0.6 23 5.1 0.0 3.7 4 0 0 4 4 3 0 AAA domain ATPase PF06745.13 EKX43920.1 - 1.1 8.6 3.6 3.3 7.0 0.0 3.2 3 0 0 3 3 3 0 KaiC Peptidase_C26 PF07722.13 EKX43921.1 - 4.1e-13 49.6 0.0 2.9e-12 46.8 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 EKX43921.1 - 1.4e-07 31.5 0.0 2e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I zf-RING_2 PF13639.6 EKX43922.1 - 6.6e-08 32.8 2.1 6.6e-08 32.8 2.1 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EKX43922.1 - 8.5e-07 28.8 0.5 8.5e-07 28.8 0.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EKX43922.1 - 5.3e-06 26.2 0.9 1.8e-05 24.5 0.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EKX43922.1 - 9.6e-06 25.2 4.2 9.6e-06 25.2 4.2 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EKX43922.1 - 3.8e-05 23.6 0.8 3.8e-05 23.6 0.8 2.5 3 0 0 3 3 3 1 RING-type zinc-finger zf-rbx1 PF12678.7 EKX43922.1 - 0.00016 21.9 2.9 0.00052 20.2 2.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EKX43922.1 - 0.0098 15.7 0.3 0.0098 15.7 0.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EKX43922.1 - 0.044 14.0 1.9 0.044 14.0 1.9 2.2 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_5 PF14634.6 EKX43922.1 - 0.074 13.0 0.7 0.074 13.0 0.7 2.2 2 0 0 2 2 2 0 zinc-RING finger domain RINGv PF12906.7 EKX43922.1 - 0.19 11.9 3.5 0.61 10.3 3.5 1.9 1 0 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.6 EKX43922.1 - 0.19 11.6 6.9 0.26 11.2 1.4 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Zf_RING PF16744.5 EKX43922.1 - 0.22 11.7 2.5 0.91 9.7 0.0 2.3 2 0 0 2 2 2 0 KIAA1045 RING finger Ac76 PF05814.11 EKX43922.1 - 9.4 6.3 9.0 5.8 7.0 4.0 2.2 2 0 0 2 2 2 0 Orf76 (Ac76) Pro_isomerase PF00160.21 EKX43923.1 - 7.9e-50 169.2 0.0 2.8e-49 167.4 0.0 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 EKX43923.1 - 9.2e-08 31.8 2.8 9.2e-08 31.8 2.8 2.4 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.15 EKX43923.1 - 9.5e-08 32.1 1.5 4.4e-06 26.8 0.1 2.5 2 0 0 2 2 2 1 U-box domain zf-NOSIP PF15906.5 EKX43923.1 - 1.4e-06 28.3 0.1 5.7e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 EKX43923.1 - 0.0023 17.9 2.2 0.036 14.1 0.4 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.8 EKX43923.1 - 0.055 13.3 11.6 0.065 13.1 0.4 4.1 3 1 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit RPAP1_N PF08621.10 EKX43923.1 - 0.19 11.5 1.6 0.27 11.0 0.5 1.8 2 0 0 2 2 2 0 RPAP1-like, N-terminal MOSC_N PF03476.16 EKX43924.1 - 7.4e-29 100.1 0.0 1.2e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 EKX43924.1 - 1.4e-23 83.3 0.0 3.6e-23 82.0 0.0 1.7 2 0 0 2 2 2 1 MOSC domain Frag1 PF10277.9 EKX43925.1 - 6.5e-25 88.0 2.5 7.8e-25 87.7 2.5 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family 7tm_1 PF00001.21 EKX43925.1 - 0.006 15.9 0.7 0.006 15.9 0.7 1.9 2 1 1 3 3 3 1 7 transmembrane receptor (rhodopsin family) MFS_Mycoplasma PF07672.13 EKX43925.1 - 0.65 9.2 4.2 0.4 9.9 1.4 2.0 2 1 0 2 2 2 0 Mycoplasma MFS transporter PB1 PF00564.24 EKX43926.1 - 4.5e-05 23.3 0.2 0.0001 22.2 0.2 1.7 1 0 0 1 1 1 1 PB1 domain HTH_38 PF13936.6 EKX43926.1 - 0.00038 20.1 0.1 0.00076 19.2 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_IclR PF09339.10 EKX43926.1 - 0.049 13.4 0.0 0.58 10.0 0.0 2.2 2 0 0 2 2 2 0 IclR helix-turn-helix domain HTH_24 PF13412.6 EKX43926.1 - 0.051 13.1 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 EKX43926.1 - 0.054 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_5 PF01022.20 EKX43926.1 - 0.099 12.5 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_Crp_2 PF13545.6 EKX43926.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Dzip-like_N PF13815.6 EKX43928.1 - 0.17 11.8 0.1 0.39 10.7 0.1 1.5 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal RWP-RK PF02042.15 EKX43929.1 - 1.2e-07 31.5 0.6 2.3e-07 30.7 0.6 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_3 PF01381.22 EKX43929.1 - 0.011 15.8 0.2 0.019 15.0 0.2 1.3 1 0 0 1 1 1 0 Helix-turn-helix HTH_37 PF13744.6 EKX43929.1 - 0.029 14.3 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.6 EKX43929.1 - 0.054 13.3 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.6 EKX43929.1 - 0.067 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 EKX43929.1 - 0.078 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_24 PF13412.6 EKX43929.1 - 0.082 12.5 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_50 PF18024.1 EKX43929.1 - 0.1 12.2 0.2 0.17 11.5 0.2 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_31 PF13560.6 EKX43929.1 - 0.13 12.7 0.1 0.23 11.8 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 EKX43929.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_19 PF12844.7 EKX43929.1 - 0.17 12.0 0.1 1.2 9.3 0.0 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain AAA_12 PF13087.6 EKX43930.1 - 4.4e-37 127.7 0.0 5.1e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EKX43930.1 - 1.4e-11 44.7 0.0 2.2e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EKX43930.1 - 0.0024 17.7 0.0 0.026 14.3 0.0 2.1 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase His_Phos_1 PF00300.22 EKX43931.1 - 1.5e-13 50.9 0.0 5.4e-13 49.1 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DnaB_C PF03796.15 EKX43931.1 - 0.085 12.2 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain zf-CCHC PF00098.23 EKX43932.1 - 3.5e-15 55.3 24.0 1.1e-06 28.4 2.8 3.5 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_2 PF13696.6 EKX43932.1 - 6.4e-07 29.1 24.1 0.00064 19.5 1.3 3.3 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_4 PF14392.6 EKX43932.1 - 7e-06 25.7 16.4 0.00048 19.8 0.2 3.1 2 1 1 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.6 EKX43932.1 - 0.014 15.3 13.4 0.34 10.9 0.5 3.0 1 1 2 3 3 3 0 Zinc knuckle zf-CCHC_5 PF14787.6 EKX43932.1 - 0.2 11.4 18.2 2 8.2 0.6 3.2 2 1 1 3 3 3 0 GAG-polyprotein viral zinc-finger Hist_deacetyl PF00850.19 EKX43933.1 - 2.5e-80 270.3 0.1 3.2e-80 269.9 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Glyco_hydro_77 PF02446.17 EKX43936.1 - 9.6e-21 74.2 0.0 1.1e-20 74.0 0.0 1.0 1 0 0 1 1 1 1 4-alpha-glucanotransferase Glyco_hydro_77 PF02446.17 EKX43937.1 - 7.7e-80 269.0 1.0 1e-73 248.8 0.8 2.1 1 1 1 2 2 2 2 4-alpha-glucanotransferase CBM_20 PF00686.19 EKX43937.1 - 1.8e-08 34.2 0.0 2.8e-06 27.1 0.0 2.6 2 0 0 2 2 2 2 Starch binding domain NinB PF05772.12 EKX43937.1 - 0.13 12.0 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 NinB protein Methyltransf_23 PF13489.6 EKX43938.1 - 0.0015 18.4 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX43938.1 - 0.011 16.4 0.0 0.024 15.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EKX43938.1 - 0.064 14.0 0.0 0.46 11.2 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 EKX43939.1 - 0.00021 21.1 0.0 0.00033 20.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 EKX43939.1 - 0.00026 20.7 0.1 0.00082 19.1 0.1 1.8 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 EKX43939.1 - 0.00041 21.0 0.2 0.0013 19.4 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain AviRa PF11599.8 EKX43939.1 - 0.0035 16.8 0.0 0.0052 16.3 0.0 1.2 1 0 0 1 1 1 1 RRNA methyltransferase AviRa MTS PF05175.14 EKX43939.1 - 0.081 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain SGL PF08450.12 EKX43940.1 - 1.2e-20 74.1 0.0 1.3e-15 57.7 0.0 2.8 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 EKX43940.1 - 0.00066 19.6 0.0 0.99 9.8 0.0 2.9 2 0 0 2 2 2 2 Two component regulator propeller Phytase-like PF13449.6 EKX43940.1 - 0.0022 18.0 0.0 0.017 15.0 0.0 2.0 2 0 0 2 2 2 1 Esterase-like activity of phytase NHL PF01436.21 EKX43940.1 - 0.15 12.1 0.0 0.77 9.9 0.0 2.2 2 0 0 2 2 2 0 NHL repeat LON_substr_bdg PF02190.16 EKX43941.1 - 4.8e-17 62.5 0.0 6.4e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Yippee-Mis18 PF03226.14 EKX43941.1 - 1.8e-07 31.3 0.2 4.2e-07 30.1 0.2 1.5 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF563 PF04577.14 EKX43942.1 - 6.7e-29 101.5 0.0 9.1e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) PDZ_6 PF17820.1 EKX43943.1 - 9.2e-10 38.2 0.0 1.4e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX43943.1 - 1.9e-06 28.1 0.0 2.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX43943.1 - 5.1e-06 26.7 0.0 6.1e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX43943.1 - 0.0034 17.3 0.0 0.0059 16.5 0.0 1.5 1 1 0 1 1 1 1 Tricorn protease PDZ domain Ank_4 PF13637.6 EKX43945.1 - 1.8e-24 85.8 1.2 4.5e-10 39.8 0.0 3.2 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX43945.1 - 3.9e-20 72.2 0.2 2.1e-10 41.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX43945.1 - 1.2e-19 70.1 0.6 1.3e-08 34.9 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX43945.1 - 9.5e-19 67.0 3.5 4.5e-07 30.0 0.3 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EKX43945.1 - 5.8e-18 63.1 2.3 3.5e-06 26.9 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat Methyltransf_25 PF13649.6 EKX43946.1 - 1.9e-13 50.9 0.1 5.1e-13 49.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX43946.1 - 5.6e-11 43.1 0.0 1.3e-10 41.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX43946.1 - 6.1e-11 42.8 0.0 1.6e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX43946.1 - 9.7e-09 35.3 3.9 2.2e-08 34.1 3.9 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX43946.1 - 2.9e-06 27.2 0.0 5.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EKX43946.1 - 0.0007 18.6 0.0 0.00098 18.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 EKX43946.1 - 0.00083 18.9 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EKX43946.1 - 0.002 18.1 0.0 0.0026 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EKX43946.1 - 0.0034 16.7 0.0 0.0046 16.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 EKX43946.1 - 0.0052 16.2 0.0 0.0083 15.6 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 EKX43946.1 - 0.033 14.1 0.0 0.093 12.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.13 EKX43946.1 - 0.074 12.4 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_PK PF05891.12 EKX43946.1 - 0.085 12.4 0.0 0.17 11.4 0.0 1.4 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase FtsJ PF01728.19 EKX43947.1 - 2.5e-18 66.8 0.1 2.8e-18 66.6 0.1 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase IncF PF17626.2 EKX43947.1 - 0.037 14.4 2.2 0.072 13.5 2.2 1.5 1 0 0 1 1 1 0 Inclusion membrane protein F Ank_5 PF13857.6 EKX43948.1 - 6.4e-12 45.5 0.2 3.3e-07 30.4 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX43948.1 - 3.7e-10 40.3 0.0 8e-10 39.2 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX43948.1 - 1.2e-09 38.5 0.1 4e-08 33.6 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX43948.1 - 2.5e-09 37.1 0.1 0.00048 20.5 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EKX43948.1 - 8.4e-06 25.8 0.1 0.11 13.2 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat DUF4502 PF14950.6 EKX43949.1 - 0.77 9.1 5.8 1.3 8.4 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) FAP206 PF12018.8 EKX43950.1 - 7.2e-43 147.1 0.2 1.4e-42 146.1 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function Complex1_49kDa PF00346.19 EKX43950.1 - 0.034 13.3 0.0 0.079 12.0 0.0 1.6 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Ank_4 PF13637.6 EKX43953.1 - 6.6e-35 119.1 0.4 3.5e-11 43.4 0.0 5.0 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX43953.1 - 7.1e-33 113.1 5.8 8.5e-11 42.3 0.0 4.2 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EKX43953.1 - 4.9e-25 86.8 4.2 3.4e-07 30.4 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 EKX43953.1 - 6.3e-20 69.2 0.7 0.0039 17.6 0.0 6.5 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EKX43953.1 - 1.7e-15 56.9 3.0 5.1e-07 29.8 0.0 5.1 2 2 3 5 5 5 4 Ankyrin repeats (many copies) DUF4116 PF13475.6 EKX43953.1 - 2.5e-13 49.5 0.0 9.5e-05 22.1 0.0 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4116) PH_6 PF15406.6 EKX43953.1 - 0.032 14.5 2.2 0.52 10.6 0.1 3.6 2 2 1 3 3 3 0 Pleckstrin homology domain PH PF00169.29 EKX43953.1 - 0.037 14.5 0.9 0.082 13.4 0.9 1.6 1 0 0 1 1 1 0 PH domain VWA_3_C PF18571.1 EKX43953.1 - 0.33 10.9 3.9 14 5.7 0.0 4.7 6 0 0 6 6 6 0 von Willebrand factor type A C-terminal domain zf-CDGSH PF09360.10 EKX43954.1 - 2.8e-09 37.0 0.2 2.8e-09 37.0 0.2 1.5 2 0 0 2 2 2 1 Iron-binding zinc finger CDGSH type ERCC3_RAD25_C PF16203.5 EKX43955.1 - 5.5e-89 297.6 0.0 8.9e-89 296.9 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 EKX43955.1 - 7.8e-16 58.5 0.0 1.6e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_3 PF13625.6 EKX43955.1 - 1.2e-12 48.1 0.0 3.1e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C PF00271.31 EKX43955.1 - 1.5e-08 34.9 0.0 3e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EKX43955.1 - 1.4e-05 24.0 0.7 0.00039 19.2 0.4 2.1 1 1 1 2 2 2 1 SNF2 family N-terminal domain DEAD PF00270.29 EKX43955.1 - 0.01 15.6 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase OppC_N PF12911.7 EKX43956.1 - 0.04 13.9 0.2 3.7 7.6 0.3 2.9 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Orn_Arg_deC_N PF02784.16 EKX43957.1 - 9.8e-76 254.4 0.0 1.2e-75 254.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EKX43957.1 - 1.3e-12 47.8 0.0 1.5e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 EKX43957.1 - 0.043 13.3 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Arabinose_Iso_C PF11762.8 EKX43957.1 - 0.16 11.8 0.0 0.46 10.3 0.0 1.7 2 0 0 2 2 2 0 L-arabinose isomerase C-terminal domain ATP_bind_2 PF03668.15 EKX43958.1 - 1.7e-25 89.9 0.0 2.3e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 P-loop ATPase protein family TH1 PF04858.13 EKX43960.1 - 9.5e-70 235.8 0.1 2.4e-60 204.8 0.2 2.0 1 1 1 2 2 2 2 TH1 protein DUF577 PF04510.12 EKX43960.1 - 0.0065 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF577) META PF03724.16 EKX43960.1 - 0.015 15.3 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 META domain DUF2249 PF10006.9 EKX43960.1 - 0.15 12.0 0.0 6.3 6.7 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2249) Denso_VP4 PF02336.15 EKX43960.1 - 0.16 10.8 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Capsid protein VP4 FHA PF00498.26 EKX43961.1 - 8.6e-18 64.5 0.1 1.6e-17 63.6 0.1 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EKX43961.1 - 2.8e-08 33.9 0.1 7.8e-08 32.5 0.1 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF881 PF05949.12 EKX43961.1 - 0.0085 16.0 0.8 1.4 8.7 0.0 3.1 4 0 0 4 4 4 2 Bacterial protein of unknown function (DUF881) EAP30 PF04157.16 EKX43961.1 - 0.06 12.6 0.3 0.19 11.0 0.0 1.8 2 0 0 2 2 2 0 EAP30/Vps36 family TPR_1 PF00515.28 EKX43962.1 - 4.6e-17 61.0 0.8 2.8e-05 23.7 0.0 5.5 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX43962.1 - 9.5e-17 59.7 1.3 0.00041 20.2 0.0 6.2 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX43962.1 - 8.3e-14 51.6 10.0 2.7e-10 40.4 0.0 4.8 4 1 1 5 5 4 2 Tetratricopeptide repeat Methyltransf_25 PF13649.6 EKX43962.1 - 3.1e-13 50.2 0.6 9.3e-13 48.7 0.2 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX43962.1 - 8e-13 48.9 0.1 2.8e-12 47.1 0.1 2.0 1 0 0 1 1 1 1 Methyltransferase domain TPR_8 PF13181.6 EKX43962.1 - 4.8e-12 45.1 0.1 0.0066 16.6 0.0 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat Methyltransf_23 PF13489.6 EKX43962.1 - 1.6e-11 44.4 0.0 3.3e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX43962.1 - 3e-11 43.4 0.4 1.4e-10 41.2 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX43962.1 - 5.3e-11 43.1 0.1 1.9e-10 41.3 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain TPR_19 PF14559.6 EKX43962.1 - 3.8e-10 40.1 3.6 0.00034 21.1 0.0 4.3 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX43962.1 - 3e-09 36.4 0.1 0.05 13.3 0.0 5.1 1 1 3 4 4 4 3 TPR repeat TPR_17 PF13431.6 EKX43962.1 - 6.9e-09 35.5 2.1 1 9.9 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX43962.1 - 2.2e-08 33.6 0.1 0.13 12.4 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX43962.1 - 2.3e-07 31.3 2.9 0.054 14.2 0.0 4.2 2 1 4 6 6 5 3 Tetratricopeptide repeat NodS PF05401.11 EKX43962.1 - 1.4e-06 28.1 0.0 3.2e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) TPR_14 PF13428.6 EKX43962.1 - 1.7e-05 25.2 0.1 12 7.0 0.0 5.5 2 2 3 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX43962.1 - 3.3e-05 24.0 0.4 0.00022 21.4 0.1 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.6 EKX43962.1 - 0.00011 21.7 0.8 0.00022 20.7 0.8 1.4 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_9 PF13371.6 EKX43962.1 - 0.00028 20.9 2.2 0.0048 17.0 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat Methyltransf_32 PF13679.6 EKX43962.1 - 0.00029 20.9 1.2 0.0011 19.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 EKX43962.1 - 0.00042 19.7 0.1 0.00077 18.8 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TPR_6 PF13174.6 EKX43962.1 - 0.00071 20.1 0.8 25 5.8 0.2 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat PrmA PF06325.13 EKX43962.1 - 0.0024 17.3 0.0 0.0054 16.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TPR_20 PF14561.6 EKX43962.1 - 0.0053 17.1 2.0 1.5 9.2 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat Ubie_methyltran PF01209.18 EKX43962.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TPR_10 PF13374.6 EKX43962.1 - 0.014 15.3 0.9 3 7.8 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat N6_N4_Mtase PF01555.18 EKX43962.1 - 0.018 14.8 0.0 0.051 13.3 0.0 1.9 2 0 0 2 2 2 0 DNA methylase MTS PF05175.14 EKX43962.1 - 0.043 13.4 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain DREV PF05219.12 EKX43962.1 - 0.064 12.3 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 DREV methyltransferase CheR PF01739.18 EKX43962.1 - 0.13 11.7 0.5 3.7 7.0 0.5 2.8 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain KIAA1430 PF13879.6 EKX43962.1 - 0.35 11.6 5.4 0.85 10.4 5.4 1.7 1 0 0 1 1 1 0 KIAA1430 homologue Sushi PF00084.20 EKX43963.1 - 0.0044 17.6 0.5 0.011 16.4 0.1 1.8 2 0 0 2 2 2 1 Sushi repeat (SCR repeat) Methyltransf_PK PF05891.12 EKX43964.1 - 4.2e-60 203.0 1.3 2.6e-59 200.4 1.3 2.2 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 EKX43964.1 - 5.1e-07 30.3 0.0 1.1e-06 29.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX43964.1 - 8.3e-06 26.4 0.0 2.1e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX43964.1 - 1.3e-05 25.1 0.0 1.9e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EKX43964.1 - 0.00089 18.6 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain CMAS PF02353.20 EKX43964.1 - 0.033 13.5 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Myb_DNA-bind_2 PF08914.11 EKX43965.1 - 5.2e-14 52.2 0.9 1.7e-13 50.5 0.9 2.0 1 0 0 1 1 1 1 Rap1 Myb domain DUF3835 PF12927.7 EKX43965.1 - 0.35 11.8 4.4 0.32 11.9 2.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3835) PTPlike_phytase PF14566.6 EKX43965.1 - 8.6 6.5 10.5 68 3.5 8.5 2.7 1 1 1 2 2 2 0 Inositol hexakisphosphate AKAP7_NLS PF10469.9 EKX43966.1 - 2.1e-14 53.9 0.0 2.7e-14 53.6 0.0 1.0 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 EKX43966.1 - 0.00021 21.2 0.0 0.0003 20.7 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Globin PF00042.22 EKX43967.1 - 0.0005 20.6 0.0 0.00087 19.8 0.0 1.4 1 0 0 1 1 1 1 Globin PPR PF01535.20 EKX43968.1 - 3e-17 61.6 0.1 0.00051 20.1 0.0 5.9 5 0 0 5 5 5 4 PPR repeat PPR_2 PF13041.6 EKX43968.1 - 2.3e-14 53.3 0.0 1.6e-05 25.0 0.0 4.9 5 0 0 5 5 5 2 PPR repeat family WW PF00397.26 EKX43968.1 - 9.6e-08 32.0 1.6 7e-05 22.8 0.1 2.6 2 0 0 2 2 2 2 WW domain PPR_3 PF13812.6 EKX43968.1 - 1.6e-06 28.1 0.0 0.0041 17.2 0.0 3.4 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 EKX43968.1 - 9.6e-06 25.2 2.9 0.018 14.7 0.0 4.4 5 0 0 5 5 5 2 PPR repeat TPR_MalT PF17874.1 EKX43968.1 - 0.0012 18.3 0.9 0.02 14.2 0.1 2.4 2 0 0 2 2 2 1 MalT-like TPR region MerR PF00376.23 EKX43968.1 - 0.044 13.5 0.0 0.18 11.6 0.0 2.1 1 0 0 1 1 1 0 MerR family regulatory protein Glyco_transf_49 PF13896.6 EKX43969.1 - 1.7e-19 70.3 0.6 8.8e-10 38.4 0.0 3.3 2 1 1 3 3 3 3 Glycosyl-transferase for dystroglycan Cyclin PF08613.11 EKX43970.1 - 1.5e-24 87.2 0.0 1.6e-24 87.1 0.0 1.0 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EKX43970.1 - 5e-06 26.3 0.0 5.7e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain UCH PF00443.29 EKX43971.1 - 2.1e-36 125.7 0.1 6.6e-36 124.1 0.1 1.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase TPR_1 PF00515.28 EKX43971.1 - 7.7e-19 66.7 5.7 1.3e-07 31.1 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX43971.1 - 2.2e-16 58.6 5.3 8.3e-06 25.5 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX43971.1 - 1.1e-12 47.1 4.5 0.0005 20.1 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat UCH_1 PF13423.6 EKX43971.1 - 2.7e-11 43.7 0.0 1.2e-10 41.5 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TPR_12 PF13424.6 EKX43971.1 - 2.8e-08 33.9 5.2 4.7e-05 23.6 1.7 3.9 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX43971.1 - 2.8e-08 33.3 2.3 0.00065 19.3 0.0 2.8 2 0 0 2 2 2 2 TPR repeat TPR_14 PF13428.6 EKX43971.1 - 3.2e-08 33.7 0.8 0.0058 17.4 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX43971.1 - 7.7e-08 31.8 1.7 0.00021 21.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX43971.1 - 1.2e-07 31.3 6.3 0.00059 19.6 0.1 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX43971.1 - 4.9e-07 30.3 2.2 0.00076 20.1 0.1 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX43971.1 - 4.2e-06 26.8 0.1 0.024 15.0 0.0 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX43971.1 - 1.2e-05 25.3 3.1 0.0039 17.2 0.1 3.0 3 0 0 3 3 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 EKX43971.1 - 2.8e-05 24.5 1.2 6.2e-05 23.4 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat USP7_C2 PF14533.6 EKX43971.1 - 3.1e-05 23.8 0.0 7.1e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal TPR_6 PF13174.6 EKX43971.1 - 0.00034 21.1 1.1 1.4 9.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX43971.1 - 0.005 17.0 0.0 0.02 15.0 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX43971.1 - 0.006 16.8 0.8 0.13 12.5 0.0 2.6 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 EKX43971.1 - 0.015 15.4 1.3 0.097 12.7 1.3 2.1 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) Peptidase_S78_2 PF14550.6 EKX43971.1 - 0.085 12.9 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 Putative phage serine protease XkdF TPR_4 PF07721.14 EKX43971.1 - 0.18 12.5 0.1 1.9 9.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat NARP1 PF12569.8 EKX43971.1 - 3.7 6.3 9.7 0.049 12.5 0.2 2.0 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 DUF5632 PF18646.1 EKX43972.1 - 0.027 14.5 0.0 0.84 9.7 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5632) PH PF00169.29 EKX43973.1 - 1.2e-67 225.0 0.0 1.4e-09 38.4 0.0 7.5 7 0 0 7 7 7 7 PH domain PH_11 PF15413.6 EKX43973.1 - 1e-30 106.3 3.4 0.035 14.5 0.0 7.9 7 0 0 7 7 7 7 Pleckstrin homology domain DUF2155 PF09923.9 EKX43973.1 - 3.6e-11 43.2 6.4 2.4 8.5 0.0 7.7 7 0 0 7 7 7 3 Uncharacterized protein conserved in bacteria (DUF2155) UVR PF02151.19 EKX43973.1 - 0.0016 18.1 0.9 0.0042 16.8 0.9 1.8 1 0 0 1 1 1 1 UvrB/uvrC motif Peptidase_S24 PF00717.23 EKX43973.1 - 0.37 10.8 2.0 3e+02 1.5 0.0 4.1 4 0 0 4 4 4 0 Peptidase S24-like Na_sulph_symp PF00939.19 EKX43975.1 - 2.9e-73 247.5 0.0 3.6e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EKX43975.1 - 7e-43 146.9 0.0 1e-23 84.0 0.0 3.0 2 1 1 3 3 3 3 Citrate transporter DSBA PF01323.20 EKX43976.1 - 1e-24 87.4 0.0 3.4e-24 85.7 0.0 1.7 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Hydrolase_4 PF12146.8 EKX43977.1 - 2e-10 40.4 0.4 0.00045 19.6 0.1 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EKX43977.1 - 7.5e-07 29.0 0.1 0.00086 19.0 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EKX43977.1 - 1.3e-05 24.8 0.1 0.006 16.1 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EKX43977.1 - 0.00029 21.5 0.5 0.0051 17.4 0.1 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 EKX43977.1 - 0.0017 18.0 0.0 0.0057 16.2 0.0 1.9 1 1 1 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.13 EKX43977.1 - 0.011 15.4 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) LIP PF03583.14 EKX43977.1 - 0.038 13.3 0.1 0.66 9.2 0.0 2.0 2 0 0 2 2 2 0 Secretory lipase p31comet PF06581.12 EKX43977.1 - 0.04 13.1 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 Mad1 and Cdc20-bound-Mad2 binding Peptidase_S15 PF02129.18 EKX43977.1 - 0.042 13.4 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PPR PF01535.20 EKX43978.1 - 2e-19 68.4 2.5 2.8e-07 30.3 0.0 6.2 5 1 1 6 6 6 4 PPR repeat PPR_2 PF13041.6 EKX43978.1 - 3.2e-19 68.9 2.2 8.6e-08 32.3 0.0 5.3 2 1 3 5 5 5 5 PPR repeat family PPR_3 PF13812.6 EKX43978.1 - 3.5e-19 68.6 0.0 1.7e-06 28.0 0.0 4.5 3 1 1 4 4 4 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 EKX43978.1 - 2.6e-12 46.2 0.0 1.8e-07 30.7 0.0 3.9 4 0 0 4 4 4 2 PPR repeat PPR_long PF17177.4 EKX43978.1 - 1.5e-05 24.5 0.0 0.067 12.5 0.0 2.6 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP TPR_7 PF13176.6 EKX43978.1 - 0.03 14.3 0.3 0.19 11.8 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat SgrR_N PF12793.7 EKX43978.1 - 0.13 12.5 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 Sugar transport-related sRNA regulator N-term COG4 PF08318.12 EKX43979.1 - 2.3e-39 135.4 6.3 3.4e-39 134.9 2.7 2.6 1 1 1 2 2 2 1 COG4 transport protein Sec15 PF04091.12 EKX43979.1 - 2.5e-08 33.7 0.2 3e-07 30.2 0.0 2.3 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec10 PF07393.11 EKX43979.1 - 8.3e-06 24.5 0.5 1.6e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Exocyst complex component Sec10 RINT1_TIP1 PF04437.13 EKX43979.1 - 0.0018 17.2 0.4 0.018 14.0 0.0 2.4 2 1 0 2 2 2 1 RINT-1 / TIP-1 family Vps53_N PF04100.12 EKX43979.1 - 0.68 8.8 5.7 5.6 5.8 2.9 2.6 2 1 0 2 2 2 0 Vps53-like, N-terminal MCU PF04678.13 EKX43979.1 - 0.73 9.9 4.1 1 9.4 1.3 2.5 2 1 0 2 2 2 0 Mitochondrial calcium uniporter Plasmid_RAQPRD PF09686.10 EKX43979.1 - 1 9.7 5.0 0.94 9.7 0.6 3.4 3 1 0 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Cupin_8 PF13621.6 EKX43980.1 - 7e-44 150.4 0.0 8.8e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EKX43980.1 - 7.4e-10 38.8 0.1 1.6e-09 37.6 0.1 1.7 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 EKX43980.1 - 0.0015 18.2 0.0 0.0054 16.4 0.0 1.9 2 0 0 2 2 2 1 Cupin domain JmjC PF02373.22 EKX43980.1 - 0.0063 16.9 0.0 0.015 15.7 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Pyr_redox_2 PF07992.14 EKX43982.1 - 5.4e-44 150.6 3.2 1.2e-43 149.4 3.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EKX43982.1 - 1.1e-25 90.6 4.2 4.7e-21 75.3 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thioredoxin PF00085.20 EKX43982.1 - 1.8e-22 79.3 0.7 3.7e-22 78.3 0.1 1.9 2 0 0 2 2 1 1 Thioredoxin Pyr_redox PF00070.27 EKX43982.1 - 2.7e-16 59.9 1.5 1.3e-12 48.1 0.7 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EKX43982.1 - 2.7e-10 39.9 7.5 0.00011 21.4 0.9 4.2 3 1 1 4 4 4 3 FAD binding domain DAO PF01266.24 EKX43982.1 - 5.1e-08 32.9 2.1 0.018 14.6 0.2 3.4 3 0 0 3 3 3 3 FAD dependent oxidoreductase HI0933_like PF03486.14 EKX43982.1 - 5.7e-07 28.6 4.4 0.012 14.4 0.9 3.6 2 1 0 3 3 3 3 HI0933-like protein FAD_oxidored PF12831.7 EKX43982.1 - 6.4e-07 29.1 2.9 3.2e-05 23.5 0.5 2.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EKX43982.1 - 1.7e-06 27.5 0.7 0.0078 15.5 0.1 3.3 3 0 0 3 3 3 2 Thi4 family NAD_binding_7 PF13241.6 EKX43982.1 - 7.4e-06 26.3 0.5 0.011 16.1 0.1 2.7 2 0 0 2 2 2 2 Putative NAD(P)-binding Thioredoxin_7 PF13899.6 EKX43982.1 - 1.2e-05 25.4 0.1 0.0044 17.2 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin-like NAD_binding_8 PF13450.6 EKX43982.1 - 7.7e-05 22.8 0.5 0.0023 18.1 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain OST3_OST6 PF04756.13 EKX43982.1 - 0.0001 21.7 0.2 0.00016 21.1 0.2 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family FAD_binding_3 PF01494.19 EKX43982.1 - 0.00041 19.7 5.8 0.011 15.0 1.0 2.7 3 0 0 3 3 3 2 FAD binding domain Thioredoxin_8 PF13905.6 EKX43982.1 - 0.00048 20.4 0.1 0.0017 18.6 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EKX43982.1 - 0.00059 20.3 0.4 0.0042 17.5 0.1 2.5 1 1 1 2 2 2 1 Thioredoxin-like domain GIDA PF01134.22 EKX43982.1 - 0.00073 18.7 15.9 0.0018 17.4 0.6 5.0 5 1 1 6 6 6 2 Glucose inhibited division protein A K_oxygenase PF13434.6 EKX43982.1 - 0.0035 16.5 0.5 0.066 12.3 0.0 2.5 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) AhpC-TSA PF00578.21 EKX43982.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family TraF PF13728.6 EKX43982.1 - 0.015 15.2 0.0 0.015 15.2 0.0 2.4 2 0 0 2 2 1 0 F plasmid transfer operon protein PALP PF00291.25 EKX43982.1 - 0.024 14.1 0.2 0.26 10.6 0.0 2.6 2 1 0 3 3 3 0 Pyridoxal-phosphate dependent enzyme Lycopene_cycl PF05834.12 EKX43982.1 - 0.025 13.7 1.6 0.15 11.0 0.6 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EKX43982.1 - 0.027 13.8 1.4 1.7 7.9 0.2 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 EKX43982.1 - 0.03 14.4 0.0 1.2 9.2 0.0 2.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ubiquitin PF00240.23 EKX43983.1 - 8e-13 48.0 0.2 1.1e-12 47.6 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EKX43983.1 - 0.00033 20.4 0.3 0.00048 19.9 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EKX43983.1 - 0.0093 15.9 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 EKX43983.1 - 0.075 13.5 0.1 0.12 12.8 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain DUF5111 PF17138.4 EKX43983.1 - 0.26 11.1 2.5 0.45 10.4 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5111) Rad60-SLD PF11976.8 EKX43984.1 - 4.6e-07 29.6 0.2 5.3e-07 29.4 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EKX43984.1 - 0.018 14.8 0.1 0.02 14.7 0.1 1.1 1 0 0 1 1 1 0 Ubiquitin family HEPN_RES_NTD1 PF18870.1 EKX43985.1 - 0.095 12.9 0.9 0.77 10.0 0.0 2.7 3 0 0 3 3 3 0 HEPN/RES N-terminal domain 1 Hist_deacetyl PF00850.19 EKX43986.1 - 1.3e-87 294.2 0.0 1.6e-87 293.8 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain Lipase_2 PF01674.18 EKX43986.1 - 0.038 13.5 0.6 0.053 13.0 0.6 1.1 1 0 0 1 1 1 0 Lipase (class 2) Aldedh PF00171.22 EKX43987.1 - 9.7e-102 340.8 0.0 1.3e-101 340.5 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AGP PF06376.12 EKX43988.1 - 0.046 13.6 0.0 13 5.8 0.0 2.2 2 0 0 2 2 2 0 Arabinogalactan peptide Keratin_matx PF04579.12 EKX43988.1 - 0.073 13.4 6.0 0.1 13.0 6.0 1.3 1 0 0 1 1 1 0 Keratin, high-sulphur matrix protein Peptidase_M23 PF01551.22 EKX43989.1 - 1.9e-14 53.6 0.0 3.2e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M23 DSPc PF00782.20 EKX43990.1 - 4.6e-21 75.0 0.0 5.8e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX43990.1 - 0.0014 18.2 0.0 0.0018 17.9 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 EKX43990.1 - 0.025 14.9 0.0 0.04 14.2 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain START PF01852.19 EKX43991.1 - 7.7e-18 64.7 0.0 1.6e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 START domain DSBA PF01323.20 EKX43991.1 - 0.079 12.7 0.8 0.12 12.1 0.1 1.6 2 0 0 2 2 2 0 DSBA-like thioredoxin domain Reticulon PF02453.17 EKX43992.1 - 4e-15 56.1 1.7 4.8e-15 55.9 1.7 1.1 1 0 0 1 1 1 1 Reticulon DUF454 PF04304.13 EKX43992.1 - 0.025 14.6 0.3 0.43 10.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF454) Transcript_VP30 PF11507.8 EKX43992.1 - 0.04 14.0 0.1 0.13 12.3 0.1 1.9 2 0 0 2 2 2 0 Ebola virus-specific transcription factor VP30 GAGA PF09237.11 EKX43993.1 - 0.43 10.4 2.0 0.91 9.4 2.0 1.5 1 0 0 1 1 1 0 GAGA factor HTH_3 PF01381.22 EKX43994.1 - 7.5e-13 48.3 0.1 1.3e-12 47.6 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EKX43994.1 - 2.1e-08 34.4 0.7 1.1e-07 32.0 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 EKX43994.1 - 0.00016 21.6 0.1 0.00024 21.0 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain MqsA_antitoxin PF15731.5 EKX43994.1 - 0.0038 17.3 0.0 0.0055 16.8 0.0 1.3 1 0 0 1 1 1 1 Antitoxin component of bacterial toxin-antitoxin system, MqsA COPIIcoated_ERV PF07970.12 EKX43995.1 - 1.5e-26 93.6 0.4 4.3e-26 92.1 0.4 1.8 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Thioredoxin PF00085.20 EKX43995.1 - 2.9e-20 72.2 0.1 5.8e-20 71.2 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin ERGIC_N PF13850.6 EKX43995.1 - 3.5e-20 72.1 0.1 9.5e-20 70.8 0.1 1.8 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Thioredoxin_2 PF13098.6 EKX43995.1 - 0.00016 22.1 0.0 0.00043 20.7 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EKX43995.1 - 0.0014 18.7 0.1 0.0033 17.6 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like PBP PF01161.20 EKX43995.1 - 0.058 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Phosphatidylethanolamine-binding protein Nucleoporin_N PF08801.11 EKX43996.1 - 0.025 13.3 0.2 0.05 12.3 0.2 1.6 1 1 0 1 1 1 0 Nup133 N terminal like RVT_1 PF00078.27 EKX43997.1 - 0.004 16.7 0.0 1.6 8.2 0.0 2.7 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) ORC5_C PF14630.6 EKX43997.1 - 0.031 13.8 0.1 0.048 13.2 0.1 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus FmiP_Thoc5 PF09766.9 EKX43999.1 - 0.0086 15.4 0.5 0.0099 15.2 0.5 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 Seryl_tRNA_N PF02403.22 EKX43999.1 - 0.12 12.6 4.5 0.16 12.2 4.5 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain HIP1_clath_bdg PF16515.5 EKX43999.1 - 0.12 13.0 3.7 0.29 11.8 3.7 1.7 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FlaC_arch PF05377.11 EKX43999.1 - 0.18 12.2 2.0 2.9 8.3 0.3 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) AAA_11 PF13086.6 EKX44000.1 - 3.7e-29 102.3 0.8 2.3e-17 63.6 0.6 3.4 2 2 1 3 3 2 2 AAA domain AAA_12 PF13087.6 EKX44000.1 - 2.4e-21 76.3 0.0 3e-20 72.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EKX44000.1 - 6.9e-08 32.9 2.9 2.4e-07 31.2 2.9 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EKX44000.1 - 1.6e-07 31.3 1.3 8.2e-07 28.9 1.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EKX44000.1 - 3.6e-05 24.1 0.5 0.00032 21.0 0.5 2.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EKX44000.1 - 0.00066 20.1 0.3 0.0045 17.4 0.3 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EKX44000.1 - 0.0017 17.8 0.0 0.0042 16.6 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein DUF2075 PF09848.9 EKX44000.1 - 0.002 17.4 0.3 0.042 13.1 0.1 2.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 EKX44000.1 - 0.01 15.9 0.0 0.032 14.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EKX44000.1 - 0.019 15.3 1.6 0.041 14.3 0.6 2.2 2 0 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.21 EKX44000.1 - 0.021 14.2 0.1 0.043 13.2 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EKX44000.1 - 0.021 14.4 0.6 0.06 12.9 0.2 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EKX44000.1 - 0.1 12.3 0.0 0.23 11.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 EKX44001.1 - 8.5e-47 159.7 0.0 1.3e-46 159.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX44001.1 - 6.3e-45 153.5 0.0 8.8e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX44001.1 - 0.00017 20.5 0.0 0.00068 18.5 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EKX44001.1 - 0.0026 17.7 0.1 0.19 11.7 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EKX44001.1 - 0.16 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like zf-Tim10_DDP PF02953.15 EKX44003.1 - 5.5e-12 45.1 0.6 7.7e-12 44.7 0.6 1.3 1 1 0 1 1 1 1 Tim10/DDP family zinc finger CPP1-like PF11833.8 EKX44004.1 - 0.16 11.6 1.3 1.3 8.6 0.1 2.6 2 1 1 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like TauE PF01925.19 EKX44004.1 - 0.49 10.0 14.7 0.081 12.5 6.8 2.8 1 1 2 3 3 3 0 Sulfite exporter TauE/SafE DoxX_2 PF13564.6 EKX44004.1 - 3.8 7.7 15.3 0.14 12.3 6.9 2.6 3 0 0 3 3 3 0 DoxX-like family DUF4191 PF13829.6 EKX44004.1 - 5.4 6.3 5.7 2.2 7.5 0.7 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) Cadherin_C_2 PF16492.5 EKX44004.1 - 9.8 7.0 5.9 5.1 7.9 0.0 2.7 2 1 0 2 2 2 0 Cadherin cytoplasmic C-terminal STN1_2 PF09170.10 EKX44005.1 - 1.3 9.2 7.4 10 6.3 0.6 2.6 2 0 0 2 2 2 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 GIDA PF01134.22 EKX44005.1 - 5.3 6.0 5.9 0.63 9.1 0.8 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A GST_C_3 PF14497.6 EKX44006.1 - 1.2e-13 51.0 0.0 1.9e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EKX44006.1 - 3.5e-07 30.1 0.0 7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EKX44006.1 - 1.4e-06 28.4 0.0 2.8e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EKX44006.1 - 3.2e-06 27.4 0.0 5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EKX44006.1 - 9e-06 26.0 0.0 1.9e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EKX44006.1 - 3.6e-05 24.0 0.0 5.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 EKX44006.1 - 0.083 13.5 0.0 0.13 12.9 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EKX44006.1 - 0.16 12.7 0.0 0.28 11.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Complex1_LYR PF05347.15 EKX44007.1 - 2.3e-20 72.4 1.9 2.6e-20 72.2 1.9 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EKX44007.1 - 4.1e-06 27.4 2.0 4.3e-06 27.4 2.0 1.0 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 EKX44007.1 - 0.0029 18.2 0.1 0.0035 17.9 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like DUF5584 PF17822.1 EKX44007.1 - 0.037 13.5 0.2 0.041 13.3 0.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5584) TPR_2 PF07719.17 EKX44009.1 - 2.4e-36 120.9 32.8 1.2e-05 25.1 0.2 10.5 9 1 1 10 10 10 9 Tetratricopeptide repeat TPR_1 PF00515.28 EKX44009.1 - 8.8e-36 120.3 28.6 9.4e-05 22.1 0.1 10.7 11 3 1 12 12 10 8 Tetratricopeptide repeat TPR_8 PF13181.6 EKX44009.1 - 6.4e-23 79.0 28.5 0.012 15.8 0.0 10.9 10 2 1 11 11 10 5 Tetratricopeptide repeat DnaJ PF00226.31 EKX44009.1 - 2e-22 79.0 6.3 2e-22 79.0 6.3 2.9 4 0 0 4 4 3 1 DnaJ domain TPR_16 PF13432.6 EKX44009.1 - 1.2e-20 73.8 10.7 3.8e-07 30.7 0.4 6.5 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 EKX44009.1 - 2.2e-18 66.5 24.5 7e-05 23.3 1.2 7.0 2 2 6 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 EKX44009.1 - 1.4e-16 59.9 11.8 0.0036 17.0 0.1 8.2 5 2 4 9 9 9 6 TPR repeat TPR_14 PF13428.6 EKX44009.1 - 2.6e-16 58.9 22.3 0.015 16.1 0.4 8.6 5 3 4 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 EKX44009.1 - 2.1e-15 56.6 14.3 2.9e-05 24.1 0.1 5.7 3 1 3 6 6 5 5 Tetratricopeptide repeat TPR_12 PF13424.6 EKX44009.1 - 3.4e-14 52.9 29.1 0.00064 20.0 0.5 7.7 4 2 5 9 9 9 6 Tetratricopeptide repeat TPR_17 PF13431.6 EKX44009.1 - 1.4e-09 37.7 8.2 0.18 12.3 0.0 7.5 7 1 0 7 7 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX44009.1 - 5.3e-09 36.2 23.3 0.0092 16.2 0.2 5.7 3 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EKX44009.1 - 4.1e-08 32.7 14.7 0.12 12.4 0.4 7.7 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 EKX44009.1 - 1.5e-06 27.6 17.2 0.013 14.8 0.4 5.6 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX44009.1 - 1.5e-05 24.6 18.2 0.05 13.0 1.0 4.1 1 1 4 5 5 5 3 MalT-like TPR region TPR_6 PF13174.6 EKX44009.1 - 0.00048 20.6 26.5 6 7.7 0.1 9.5 9 1 1 10 10 9 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX44009.1 - 0.00069 19.4 25.8 0.069 13.0 0.4 7.5 9 0 0 9 9 7 2 Tetratricopeptide repeat RPT PF13446.6 EKX44009.1 - 0.0066 16.3 2.0 0.039 13.9 0.1 2.9 2 0 0 2 2 2 1 A repeated domain in UCH-protein Fis1_TPR_C PF14853.6 EKX44009.1 - 0.0095 16.0 14.7 4.2 7.5 0.0 7.1 4 3 4 8 8 8 1 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 EKX44009.1 - 0.012 16.0 0.2 0.012 16.0 0.2 4.9 3 2 2 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 EKX44009.1 - 0.016 15.3 19.4 0.2 11.8 0.1 5.4 5 1 1 6 6 5 0 MIT (microtubule interacting and transport) domain HSP20 PF00011.21 EKX44009.1 - 0.017 15.2 0.8 0.042 14.0 0.8 1.6 1 0 0 1 1 1 0 Hsp20/alpha crystallin family Desmo_N PF06771.11 EKX44009.1 - 0.03 14.7 0.2 2.2 8.7 0.0 3.0 3 0 0 3 3 2 0 Viral Desmoplakin N-terminus TPR_4 PF07721.14 EKX44009.1 - 0.04 14.5 19.2 1.3 9.9 0.8 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Ank_2 PF12796.7 EKX44009.1 - 0.065 13.8 0.3 0.14 12.7 0.3 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) NARP1 PF12569.8 EKX44009.1 - 0.079 11.9 32.8 0.43 9.4 5.6 4.4 2 2 3 5 5 5 0 NMDA receptor-regulated protein 1 SLATT_1 PF18181.1 EKX44009.1 - 0.088 12.7 1.4 0.26 11.2 0.1 2.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 ChAPs PF09295.10 EKX44009.1 - 0.14 11.1 4.4 1.7 7.6 0.0 2.7 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF627 PF04781.12 EKX44009.1 - 0.23 11.5 12.4 0.88 9.6 0.0 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF627) Latarcin PF10279.9 EKX44009.1 - 0.6 10.6 8.0 2.3 8.7 4.0 3.6 2 2 0 2 2 2 0 Latarcin precursor YfdX PF10938.8 EKX44009.1 - 0.95 9.4 28.5 0.11 12.5 8.2 4.7 3 3 0 3 3 3 0 YfdX protein DUF982 PF06169.12 EKX44009.1 - 1.5 9.0 5.2 25 5.0 0.3 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF982) SHNi-TPR PF10516.9 EKX44009.1 - 2.1 7.9 13.1 4.4 6.9 0.1 5.0 6 0 0 6 6 5 0 SHNi-TPR Kelch_1 PF01344.25 EKX44011.1 - 1.3e-56 187.9 6.2 5.1e-11 42.0 0.0 6.8 6 1 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 EKX44011.1 - 8e-34 114.8 3.7 8.6e-07 29.0 0.0 7.1 3 2 3 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EKX44011.1 - 2.4e-32 110.7 0.8 5.6e-09 35.9 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 EKX44011.1 - 1.6e-23 81.7 8.1 6.2e-05 22.8 0.0 6.6 6 1 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EKX44011.1 - 2.5e-22 78.6 0.3 0.00014 22.0 0.0 6.9 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EKX44011.1 - 7.2e-19 67.4 0.9 0.03 14.3 0.0 6.2 6 0 0 6 6 6 5 Kelch motif DUF1668 PF07893.13 EKX44011.1 - 0.00012 21.5 0.0 0.00059 19.3 0.0 2.0 1 1 0 2 2 2 1 Protein of unknown function (DUF1668) MoaF PF10703.9 EKX44011.1 - 0.11 12.4 0.0 3 7.8 0.0 2.8 3 0 0 3 3 3 0 MoaF N-terminal domain MS_channel PF00924.18 EKX44012.1 - 1e-34 119.9 0.6 1.5e-34 119.3 0.6 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel Gaa1 PF04114.14 EKX44012.1 - 0.014 14.5 2.3 0.018 14.1 2.3 1.1 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component DUF4257 PF14074.6 EKX44012.1 - 0.2 11.9 3.5 0.77 10.0 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4257) DUF2393 PF09624.10 EKX44012.1 - 0.97 9.4 4.0 0.24 11.4 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) Thioredoxin PF00085.20 EKX44013.1 - 1.4e-05 25.0 0.1 3.9e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 EKX44013.1 - 0.00029 19.9 1.2 0.00033 19.7 0.8 1.3 1 1 0 1 1 1 1 Phosducin SPT6_acidic PF14632.6 EKX44013.1 - 3.8 8.2 14.3 0.83 10.3 5.4 2.4 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Pkinase PF00069.25 EKX44014.1 - 3.5e-68 229.8 0.0 4.1e-68 229.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX44014.1 - 1.2e-37 129.6 0.0 1.5e-37 129.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX44014.1 - 3.4e-09 36.5 0.0 7.3e-09 35.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EKX44014.1 - 1.7e-05 24.9 0.1 8.1e-05 22.7 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX44014.1 - 3.1e-05 23.4 0.3 9.6e-05 21.8 0.1 1.8 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EKX44014.1 - 0.0014 17.7 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EKX44014.1 - 0.0036 17.0 0.0 1.8 8.2 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EKX44014.1 - 0.0086 15.7 0.0 0.027 14.1 0.0 1.7 1 1 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 EKX44014.1 - 0.012 14.5 0.0 0.024 13.4 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase YjhX_toxin PF09857.9 EKX44014.1 - 0.037 14.0 0.1 0.14 12.1 0.1 1.9 2 0 0 2 2 2 0 Putative toxin of bacterial toxin-antitoxin pair Seadorna_VP7 PF07387.11 EKX44014.1 - 0.12 11.4 0.1 0.38 9.8 0.0 1.8 2 0 0 2 2 2 0 Seadornavirus VP7 Pox_A_type_inc PF04508.12 EKX44015.1 - 0.00051 19.8 0.2 0.11 12.4 0.1 2.7 2 0 0 2 2 2 1 Viral A-type inclusion protein repeat HTH_6 PF01418.17 EKX44015.1 - 0.073 13.1 1.2 0.18 11.8 1.2 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family AAA_13 PF13166.6 EKX44015.1 - 0.12 11.0 17.8 0.17 10.5 17.8 1.2 1 0 0 1 1 1 0 AAA domain Bcr-Abl_Oligo PF09036.10 EKX44015.1 - 0.36 10.9 3.1 0.45 10.6 0.5 2.3 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain EMP24_GP25L PF01105.24 EKX44015.1 - 1.4 8.8 9.2 0.57 10.1 0.9 2.4 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD NPV_P10 PF05531.12 EKX44015.1 - 3.3 8.2 6.2 29 5.2 1.0 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Allexi_40kDa PF05549.11 EKX44015.1 - 4.3 6.8 19.1 0.75 9.3 4.5 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF3573 PF12097.8 EKX44015.1 - 9.6 4.9 9.4 0.65 8.8 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) Met_synt_B12 PF02965.17 EKX44016.1 - 1.6e-121 405.0 0.0 2.6e-121 404.3 0.0 1.3 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 EKX44016.1 - 3.6e-75 253.2 0.0 6.3e-75 252.4 0.0 1.4 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 EKX44016.1 - 2.3e-51 174.8 0.4 2.2e-50 171.6 0.1 2.3 2 0 0 2 2 2 1 Pterin binding enzyme B12-binding_2 PF02607.17 EKX44016.1 - 2.6e-23 82.3 0.1 2.6e-23 82.3 0.1 2.5 3 0 0 3 3 3 1 B12 binding domain B12-binding PF02310.19 EKX44016.1 - 4e-20 72.1 0.8 4.5e-19 68.7 0.3 2.8 2 0 0 2 2 2 1 B12 binding domain Ephrin_rec_like PF07699.13 EKX44017.1 - 2.9e-10 39.7 1.2 4.3e-06 26.4 0.7 2.2 2 0 0 2 2 2 2 Putative ephrin-receptor like NCD3G PF07562.14 EKX44017.1 - 0.013 15.5 1.6 0.042 13.8 0.3 2.1 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR DERM PF14704.6 EKX44017.1 - 0.072 13.6 0.0 0.088 13.3 0.0 1.1 1 0 0 1 1 1 0 Dermatopontin PDZ PF00595.24 EKX44019.1 - 3.4e-09 36.9 0.0 8.7e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX44019.1 - 1.2e-07 31.4 0.1 3.6e-07 29.9 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX44019.1 - 8.1e-05 22.9 0.0 0.00026 21.3 0.0 1.9 1 0 0 1 1 1 1 PDZ domain TFIIA PF03153.13 EKX44019.1 - 0.0093 16.0 5.2 0.016 15.3 5.2 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CDC27 PF09507.10 EKX44019.1 - 0.053 12.9 8.9 0.089 12.2 8.9 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TT1725 PF18324.1 EKX44019.1 - 0.093 12.8 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Hypothetical protein TT1725 DUF4746 PF15928.5 EKX44019.1 - 0.13 11.7 12.2 0.21 11.0 12.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PPP4R2 PF09184.11 EKX44019.1 - 0.14 11.7 13.6 0.28 10.7 13.6 1.4 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 EKX44019.1 - 0.23 10.8 13.4 0.39 10.0 13.4 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 EKX44019.1 - 0.88 7.7 20.6 1.4 7.0 20.6 1.2 1 0 0 1 1 1 0 Nop14-like family Arm PF00514.23 EKX44019.1 - 0.91 9.7 3.0 76 3.6 0.0 3.9 4 0 0 4 4 3 0 Armadillo/beta-catenin-like repeat RNA_pol_Rpc4 PF05132.14 EKX44019.1 - 1.3 9.4 4.6 2 8.8 3.1 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 SDA1 PF05285.12 EKX44019.1 - 1.6 8.1 20.6 2.8 7.3 20.6 1.3 1 0 0 1 1 1 0 SDA1 AIF_C PF14721.6 EKX44019.1 - 1.9 8.8 4.8 33 4.8 4.1 2.5 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Connexin PF00029.19 EKX44019.1 - 2.6 7.7 4.9 5.5 6.7 4.9 1.4 1 0 0 1 1 1 0 Connexin TRAP_alpha PF03896.16 EKX44019.1 - 3.4 6.8 10.7 5.9 6.0 10.7 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Presenilin PF01080.17 EKX44019.1 - 3.6 6.3 6.3 6.1 5.5 6.3 1.3 1 0 0 1 1 1 0 Presenilin RNA_pol_3_Rpc31 PF11705.8 EKX44019.1 - 4.5 7.5 23.0 8.1 6.6 23.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 VIR_N PF15912.5 EKX44019.1 - 6.2 6.3 10.6 11 5.5 10.6 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal CobT PF06213.12 EKX44019.1 - 6.7 6.0 18.8 3 7.2 16.1 1.7 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.12 EKX44019.1 - 8.1 5.7 18.6 13 4.9 18.6 1.2 1 0 0 1 1 1 0 NOA36 protein Nucleo_P87 PF07267.11 EKX44019.1 - 8.7 5.1 7.1 13 4.5 7.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF3568 PF12092.8 EKX44020.1 - 7.7 6.6 7.6 0.34 11.0 1.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3568) HMG_box PF00505.19 EKX44022.1 - 2.4e-44 149.6 7.1 6.8e-24 84.1 0.8 2.1 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EKX44022.1 - 2.2e-31 108.3 7.2 7.1e-17 61.8 0.8 2.7 2 1 0 2 2 2 2 HMG-box domain CHDNT PF08073.12 EKX44022.1 - 7.6e-10 38.6 0.0 1.1e-07 31.7 0.0 2.4 2 0 0 2 2 2 2 CHDNT (NUC034) domain Imm58 PF15581.6 EKX44022.1 - 0.023 14.8 0.2 0.46 10.6 0.0 2.1 2 0 0 2 2 2 0 Immunity protein 58 TTL PF03133.15 EKX44023.1 - 6.9e-13 48.4 0.0 3.4e-07 29.7 0.0 2.4 2 1 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EKX44023.1 - 0.0012 18.2 0.0 0.081 12.2 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp PPR_1 PF12854.7 EKX44025.1 - 3 7.6 11.8 39 4.1 0.2 5.8 6 0 0 6 6 6 0 PPR repeat Pkinase PF00069.25 EKX44026.1 - 1.3e-17 64.1 0.0 1.9e-17 63.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX44026.1 - 8.1e-06 25.3 0.0 1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX44026.1 - 0.00077 18.9 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX44026.1 - 0.0054 16.7 0.0 0.0074 16.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EKX44026.1 - 0.0088 15.7 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 NUDE_C PF04880.13 EKX44027.1 - 0.0049 17.4 3.1 0.0065 17.0 3.1 1.2 1 0 0 1 1 1 1 NUDE protein, C-terminal conserved region Caldesmon PF02029.15 EKX44033.1 - 0.00053 18.9 31.3 0.00081 18.3 31.3 1.3 1 0 0 1 1 1 1 Caldesmon Plasmodium_Vir PF05795.11 EKX44033.1 - 0.0011 18.4 11.7 0.0017 17.9 11.7 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Presenilin PF01080.17 EKX44033.1 - 0.0048 15.7 25.1 0.0068 15.2 25.1 1.1 1 0 0 1 1 1 1 Presenilin Spore_coat_CotO PF14153.6 EKX44033.1 - 0.0052 16.7 27.4 0.0094 15.9 27.4 1.4 1 0 0 1 1 1 1 Spore coat protein CotO DUF4045 PF13254.6 EKX44033.1 - 0.0069 16.1 16.2 0.0085 15.8 16.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4045) CCSAP PF15748.5 EKX44033.1 - 0.036 14.2 23.3 0.065 13.4 23.3 1.4 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated BUD22 PF09073.10 EKX44033.1 - 0.037 13.4 42.1 0.055 12.8 42.1 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 EKX44033.1 - 0.17 10.1 46.3 0.25 9.5 46.3 1.2 1 0 0 1 1 1 0 Nop14-like family NPR3 PF03666.13 EKX44033.1 - 0.17 10.6 23.8 0.25 10.1 23.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SDA1 PF05285.12 EKX44033.1 - 0.22 10.9 47.8 0.39 10.1 47.8 1.3 1 0 0 1 1 1 0 SDA1 MDM1 PF15501.6 EKX44033.1 - 0.42 9.7 29.1 0.62 9.1 29.1 1.2 1 0 0 1 1 1 0 Nuclear protein MDM1 SAPS PF04499.15 EKX44033.1 - 0.44 9.3 22.2 0.56 8.9 22.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.16 EKX44033.1 - 0.47 10.5 7.7 0.8 9.7 7.7 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region XRN_M PF17846.1 EKX44033.1 - 0.78 8.6 16.2 1.1 8.2 16.2 1.2 1 0 0 1 1 1 0 Xrn1 helical domain Endostatin PF06482.11 EKX44033.1 - 1.1 8.7 8.0 1.6 8.1 8.0 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Peptidase_S64 PF08192.11 EKX44033.1 - 1.7 7.0 15.3 2.3 6.6 15.3 1.2 1 0 0 1 1 1 0 Peptidase family S64 Lin-8 PF03353.15 EKX44033.1 - 1.9 8.0 26.2 3.2 7.3 26.2 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Vfa1 PF08432.10 EKX44033.1 - 3.3 8.0 31.3 8.4 6.7 31.3 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SID-1_RNA_chan PF13965.6 EKX44033.1 - 5.8 5.2 8.1 9 4.6 8.1 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TFIIF_alpha PF05793.12 EKX44033.1 - 7 5.1 47.6 9.9 4.6 47.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cwf_Cwc_15 PF04889.12 EKX44033.1 - 8.5 6.0 43.5 15 5.2 43.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PX PF00787.24 EKX44034.1 - 5.9e-21 74.6 0.3 7.2e-21 74.3 0.3 1.1 1 0 0 1 1 1 1 PX domain DUF1676 PF07898.13 EKX44035.1 - 0.0029 17.7 13.8 0.0029 17.7 13.8 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1676) UPF0122 PF04297.14 EKX44035.1 - 0.012 15.8 0.8 0.012 15.8 0.8 2.1 2 0 0 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like EMC3_TMCO1 PF01956.16 EKX44035.1 - 0.013 15.3 16.6 0.013 15.3 16.6 2.5 2 1 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like DUF2031 PF09592.10 EKX44035.1 - 0.024 14.2 5.8 0.055 13.0 5.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) Orf78 PF06024.12 EKX44035.1 - 0.025 14.9 1.9 0.071 13.4 1.9 1.7 1 0 0 1 1 1 0 Orf78 (ac78) Claudin_2 PF13903.6 EKX44035.1 - 0.038 13.8 2.2 0.061 13.1 2.2 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Ac81 PF05820.11 EKX44035.1 - 0.23 11.0 3.6 0.39 10.3 3.6 1.3 1 0 0 1 1 1 0 Baculoviridae AC81 TraG_N PF07916.11 EKX44035.1 - 0.52 9.1 13.3 0.73 8.6 13.3 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF454 PF04304.13 EKX44035.1 - 0.82 9.7 13.8 0.29 11.2 8.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF454) Pkinase PF00069.25 EKX44037.1 - 1.4e-15 57.4 0.0 3.6e-15 56.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX44037.1 - 1.9e-14 53.6 0.0 1e-13 51.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX44037.1 - 0.044 13.7 0.7 0.45 10.4 0.4 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family EphA2_TM PF14575.6 EKX44038.1 - 0.023 15.5 0.0 0.032 15.1 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMIE PF16038.5 EKX44038.1 - 0.095 12.6 1.8 0.16 11.8 1.8 1.3 1 0 0 1 1 1 0 TMIE protein PsbX PF06596.11 EKX44038.1 - 0.15 12.1 0.3 0.26 11.3 0.3 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) tRNA_m1G_MT PF01746.21 EKX44039.1 - 1.6e-12 47.5 0.0 1.8e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Cas_St_Csn2 PF16813.5 EKX44040.1 - 0.18 10.9 0.1 0.24 10.5 0.1 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Csn2 subfamily St RRM_1 PF00076.22 EKX44041.1 - 0.00018 21.3 0.0 0.064 13.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LPP PF04728.13 EKX44041.1 - 0.041 14.3 3.2 1.6 9.2 0.0 3.1 2 0 0 2 2 2 0 Lipoprotein leucine-zipper RRM_occluded PF16842.5 EKX44041.1 - 0.14 12.1 0.0 3.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif YtxH PF12732.7 EKX44041.1 - 2 9.0 5.2 0.66 10.6 0.4 2.3 2 1 0 2 2 2 0 YtxH-like protein WD40 PF00400.32 EKX44042.1 - 7.5e-55 181.7 18.7 3.1e-08 34.1 0.2 8.8 9 0 0 9 9 9 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX44042.1 - 3.6e-25 88.1 1.0 0.00034 20.8 0.1 5.7 1 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EKX44042.1 - 3.4e-08 32.6 5.5 0.093 11.4 0.0 4.1 3 1 2 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EKX44042.1 - 8.3e-08 31.6 2.0 0.31 9.9 0.1 5.6 2 2 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EKX44042.1 - 0.00026 20.4 0.0 0.069 12.5 0.0 2.5 1 1 0 2 2 2 2 WD40-like domain GATase_2 PF00310.21 EKX44042.1 - 0.026 13.3 0.0 0.034 12.9 0.0 1.1 1 0 0 1 1 1 0 Glutamine amidotransferases class-II PD40 PF07676.12 EKX44042.1 - 0.042 13.8 0.0 76 3.4 0.0 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PALB2_WD40 PF16756.5 EKX44042.1 - 0.36 9.7 4.5 4.5 6.1 0.0 3.6 3 2 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Methyltransf_21 PF05050.12 EKX44043.1 - 1.8e-05 24.8 0.0 3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain LLC1 PF14945.6 EKX44045.1 - 0.13 12.9 0.4 0.21 12.2 0.2 1.5 1 1 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Tropomyosin_1 PF12718.7 EKX44046.1 - 0.0092 16.1 14.3 0.0092 16.1 14.3 3.1 2 1 0 2 2 2 1 Tropomyosin like ApoLp-III PF07464.11 EKX44046.1 - 0.013 15.6 0.3 0.029 14.5 0.3 1.6 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) NPV_P10 PF05531.12 EKX44046.1 - 0.065 13.7 0.2 3.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FUSC PF04632.12 EKX44046.1 - 0.1 11.1 1.2 0.16 10.5 1.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Exonuc_VII_L PF02601.15 EKX44046.1 - 0.56 9.7 5.6 0.94 9.0 5.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FeoC PF09012.10 EKX44046.1 - 1 9.5 4.9 0.41 10.7 1.4 2.1 2 0 0 2 2 2 0 FeoC like transcriptional regulator DUF4834 PF16118.5 EKX44046.1 - 4.9 8.2 0.0 4.9 8.2 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Nramp PF01566.18 EKX44047.1 - 1.7e-122 408.8 24.9 2.5e-122 408.3 24.9 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein SlyX PF04102.12 EKX44048.1 - 0.00019 22.0 5.9 0.00019 22.0 5.9 3.5 2 1 1 3 3 3 1 SlyX DivIC PF04977.15 EKX44048.1 - 0.0032 17.2 7.0 0.0032 17.2 7.0 3.3 2 1 1 3 3 3 1 Septum formation initiator KxDL PF10241.9 EKX44048.1 - 0.043 14.1 1.9 0.043 14.1 1.9 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein ATG16 PF08614.11 EKX44048.1 - 0.27 11.4 27.8 0.48 10.6 18.7 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Macoilin PF09726.9 EKX44048.1 - 0.37 9.3 17.4 0.47 8.9 17.4 1.2 1 0 0 1 1 1 0 Macoilin family YabA PF06156.13 EKX44048.1 - 0.51 11.0 20.2 0.89 10.2 4.8 3.0 2 1 1 3 3 3 0 Initiation control protein YabA YojJ PF10372.9 EKX44048.1 - 0.52 10.4 3.1 0.57 10.3 0.5 2.4 2 1 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus FlaC_arch PF05377.11 EKX44048.1 - 0.57 10.6 6.6 8.6 6.8 1.2 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 EKX44048.1 - 0.76 9.8 9.6 0.83 9.7 7.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) STAT_alpha PF01017.20 EKX44048.1 - 1.2 9.0 19.1 5.2 6.9 9.5 2.7 2 1 0 2 2 2 0 STAT protein, all-alpha domain CENP-H PF05837.12 EKX44048.1 - 1.2 9.6 27.0 0.081 13.3 8.7 2.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) V_ATPase_I PF01496.19 EKX44048.1 - 1.3 6.9 9.5 1.7 6.5 9.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Bacillus_HBL PF05791.11 EKX44048.1 - 1.3 8.8 7.5 0.18 11.6 3.0 1.8 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) EMP24_GP25L PF01105.24 EKX44048.1 - 4.3 7.2 15.4 13 5.7 3.0 2.8 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD TMEM192 PF14802.6 EKX44048.1 - 5.9 5.9 6.9 1.4 8.0 3.2 1.7 2 0 0 2 2 2 0 TMEM192 family Spc7 PF08317.11 EKX44048.1 - 6.3 5.6 25.0 9.2 5.0 23.4 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.10 EKX44048.1 - 9.1 6.5 16.5 1.3 9.2 10.1 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Lyase_1 PF00206.20 EKX44049.1 - 8.7e-44 150.2 0.0 1.5e-43 149.4 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C PF08328.11 EKX44049.1 - 1.7e-40 137.7 0.1 2.8e-40 137.0 0.1 1.4 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal DUF4111 PF13427.6 EKX44049.1 - 0.13 12.4 0.0 0.39 10.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) Histone PF00125.24 EKX44049.1 - 0.13 12.6 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 PDZ_6 PF17820.1 EKX44050.1 - 3.3e-07 30.0 0.3 8.4e-07 28.7 0.3 1.7 1 0 0 1 1 1 1 PDZ domain Spc42p PF11544.8 EKX44050.1 - 0.039 13.9 0.3 0.039 13.9 0.3 2.6 2 0 0 2 2 2 0 Spindle pole body component Spc42p BLOC1_2 PF10046.9 EKX44050.1 - 0.046 14.0 3.6 0.049 13.9 0.6 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1192 PF06698.11 EKX44050.1 - 0.046 13.8 11.4 0.034 14.2 2.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) PDZ PF00595.24 EKX44050.1 - 0.054 13.8 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 PDZ domain Pox_A11 PF05061.13 EKX44050.1 - 0.22 10.8 1.8 1.5 8.1 0.2 2.2 2 0 0 2 2 2 0 Poxvirus A11 Protein Bap31_Bap29_C PF18035.1 EKX44050.1 - 0.72 9.9 7.9 4.1 7.5 0.3 2.7 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Paralemmin PF03285.15 EKX44050.1 - 5.9 6.4 13.9 0.36 10.4 2.2 3.0 3 0 0 3 3 3 0 Paralemmin OTU PF02338.19 EKX44051.1 - 7.2e-15 55.6 0.0 1.3e-14 54.8 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EKX44051.1 - 0.16 11.4 2.0 1.4 8.3 0.1 2.5 2 1 0 3 3 3 0 Peptidase C65 Otubain Ammonium_transp PF00909.21 EKX44052.1 - 8.4e-124 413.3 26.8 1e-123 413.0 26.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF1129 PF06570.11 EKX44052.1 - 4.9 6.6 7.3 64 2.9 0.0 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) SRA1 PF07304.11 EKX44053.1 - 3.5e-06 26.9 13.9 5.4e-06 26.3 10.7 2.9 2 1 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.7 EKX44053.1 - 9.2e-05 22.2 0.5 0.003 17.3 0.5 2.6 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 WD40 PF00400.32 EKX44053.1 - 0.00016 22.4 9.5 24 6.0 0.0 7.4 7 1 0 7 7 7 1 WD domain, G-beta repeat Spore_YhcN_YlaJ PF09580.10 EKX44053.1 - 0.0014 18.7 0.0 0.0029 17.7 0.0 1.4 1 0 0 1 1 1 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) TFIIA PF03153.13 EKX44053.1 - 2.2 8.2 43.0 0.22 11.5 38.1 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2457 PF10446.9 EKX44053.1 - 6.1 5.9 11.4 11 5.0 11.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PGI PF00342.19 EKX44054.1 - 8.5e-125 417.1 0.0 1.2e-124 416.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoglucose isomerase Mur_ligase PF01225.25 EKX44054.1 - 0.13 12.6 0.0 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 Mur ligase family, catalytic domain Mito_carr PF00153.27 EKX44055.1 - 3e-54 180.9 0.3 5.9e-18 64.6 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.16 EKX44055.1 - 0.0058 16.5 0.0 0.78 9.7 0.0 2.4 2 0 0 2 2 2 2 UcrQ family HMD PF03201.16 EKX44055.1 - 0.12 12.6 0.1 0.74 10.1 0.2 2.0 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase WD40 PF00400.32 EKX44057.1 - 7.1e-10 39.3 0.0 0.066 14.1 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX44057.1 - 0.00013 22.2 0.0 0.065 13.5 0.0 2.3 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DNA_repr_REX1B PF14966.6 EKX44058.1 - 0.075 13.7 0.1 3.3 8.4 0.0 2.8 2 1 0 2 2 2 0 DNA repair REX1-B PG_binding_3 PF09374.10 EKX44058.1 - 0.075 13.3 0.1 5.4 7.3 0.0 2.6 2 0 0 2 2 2 0 Predicted Peptidoglycan domain WD40 PF00400.32 EKX44059.1 - 2.5e-05 24.9 0.0 0.29 12.1 0.0 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX44059.1 - 0.0051 17.1 0.0 0.045 14.0 0.0 2.0 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Ank_5 PF13857.6 EKX44061.1 - 2.3e-07 30.9 0.0 2.4e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX44061.1 - 3.6e-06 27.5 0.1 0.0023 18.5 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX44061.1 - 7.5e-05 23.2 0.2 0.00019 21.9 0.0 2.0 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX44061.1 - 0.00022 21.5 0.0 0.0012 19.2 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EKX44061.1 - 0.00022 21.4 0.0 0.0018 18.6 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Rad21_Rec8 PF04824.16 EKX44064.1 - 9.4e-09 34.4 0.1 5.8e-08 31.9 0.0 2.0 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein Noc2 PF03715.13 EKX44064.1 - 0.075 12.3 0.2 0.11 11.8 0.2 1.1 1 0 0 1 1 1 0 Noc2p family Rad21_Rec8_N PF04825.13 EKX44065.1 - 7.6e-34 116.2 0.1 9.1e-34 115.9 0.1 1.1 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein CNDH2_N PF06278.11 EKX44065.1 - 0.035 14.3 0.0 0.047 13.9 0.0 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal DUF1699 PF08004.11 EKX44065.1 - 0.046 13.4 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) ObR_Ig PF18589.1 EKX44066.1 - 0.17 12.3 0.8 11 6.5 0.1 3.5 3 0 0 3 3 3 0 Obesity receptor immunoglobulin like domain SK_channel PF03530.14 EKX44067.1 - 6.5e-08 32.6 1.2 1.8e-06 27.9 1.2 2.5 1 1 0 1 1 1 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.16 EKX44067.1 - 0.00081 19.3 2.1 0.0025 17.8 2.1 1.8 1 0 0 1 1 1 1 Ion channel RRN3 PF05327.11 EKX44068.1 - 0.22 10.0 8.1 0.31 9.5 8.1 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.12 EKX44068.1 - 0.33 10.2 20.2 0.62 9.3 20.2 1.5 1 0 0 1 1 1 0 NOA36 protein GCIP PF13324.6 EKX44068.1 - 1 8.9 5.8 1.7 8.2 5.8 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Sporozoite_P67 PF05642.11 EKX44068.1 - 1.4 6.9 4.7 2.5 6.1 4.7 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BUD22 PF09073.10 EKX44068.1 - 1.6 8.0 16.7 0.22 10.9 9.5 2.2 2 0 0 2 2 2 0 BUD22 Sigma70_ner PF04546.13 EKX44068.1 - 3.5 7.5 12.0 0.4 10.5 6.7 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Peptidase_M13_N PF05649.13 EKX44069.1 - 1.7e-92 311.0 0.0 2.5e-92 310.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 EKX44069.1 - 7.4e-66 221.7 0.0 1.3e-65 220.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 DUF1796 PF08795.10 EKX44069.1 - 0.05 13.6 0.3 0.66 9.9 0.1 2.3 2 0 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) ABC_tran PF00005.27 EKX44070.1 - 0.1 13.1 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter ABC2_membrane_3 PF12698.7 EKX44070.1 - 4.8 6.2 6.2 27 3.7 5.8 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein Helicase_C PF00271.31 EKX44074.1 - 5.1e-16 59.0 0.2 2.7e-15 56.7 0.0 2.3 3 0 0 3 3 2 1 Helicase conserved C-terminal domain UvrB PF12344.8 EKX44074.1 - 2.8e-13 49.5 0.2 7.1e-13 48.2 0.2 1.7 1 0 0 1 1 1 1 Ultra-violet resistance protein B ResIII PF04851.15 EKX44074.1 - 5.8e-13 49.2 0.0 3.5e-12 46.6 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EKX44074.1 - 3.2e-07 30.3 0.0 4e-05 23.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain UvrB_inter PF17757.1 EKX44074.1 - 2.6e-05 24.3 0.0 6.6e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 UvrB interaction domain AAA_19 PF13245.6 EKX44074.1 - 0.00031 21.1 1.0 0.73 10.2 0.3 3.1 2 1 0 2 2 2 2 AAA domain DEAD PF00270.29 EKX44074.1 - 0.00034 20.4 0.0 0.0049 16.7 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase Kinesin PF00225.23 EKX44074.1 - 0.00089 18.3 0.0 0.0014 17.6 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain AAA_16 PF13191.6 EKX44074.1 - 0.0035 17.8 0.0 0.016 15.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 EKX44074.1 - 0.026 14.0 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 EKX44074.1 - 0.032 14.5 0.1 0.23 11.7 0.0 2.5 3 1 0 3 3 3 0 AAA domain UvrD-helicase PF00580.21 EKX44074.1 - 0.053 13.0 0.1 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain RuvB_N PF05496.12 EKX44074.1 - 0.095 12.4 0.1 13 5.4 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 EKX44074.1 - 0.096 13.1 0.7 6.8 7.1 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EKX44074.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DAP3 PF10236.9 EKX44074.1 - 0.18 11.0 0.0 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_11 PF13086.6 EKX44074.1 - 0.47 10.2 1.8 5.4 6.7 0.0 2.5 2 1 0 3 3 3 0 AAA domain DUF3926 PF13080.6 EKX44076.1 - 0.054 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) TPR_12 PF13424.6 EKX44078.1 - 3.7e-05 23.9 4.5 0.1 12.9 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat DUF627 PF04781.12 EKX44078.1 - 0.048 13.7 0.2 0.18 11.8 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF627) Chlam_PMP PF02415.17 EKX44080.1 - 6.4e-07 29.5 3.6 0.03 14.8 0.1 3.3 3 0 0 3 3 3 3 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Pentapeptide_3 PF13576.6 EKX44080.1 - 0.0091 16.1 6.6 0.4 10.9 1.2 2.7 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Antifungal_prot PF11402.8 EKX44080.1 - 0.1 12.8 0.4 19 5.6 0.0 2.6 2 1 1 3 3 3 0 Antifungal protein Pkinase PF00069.25 EKX44084.1 - 1.4e-35 123.0 0.0 2.3e-35 122.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX44084.1 - 4.8e-12 45.7 0.0 3.9e-08 32.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX44084.1 - 0.0054 15.6 0.0 0.0077 15.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase MFS_1 PF07690.16 EKX44085.1 - 1.5e-19 70.1 15.2 1.5e-19 70.1 15.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily LemA PF04011.12 EKX44086.1 - 0.033 14.0 2.3 0.037 13.9 0.2 1.9 2 0 0 2 2 2 0 LemA family RSS_P20 PF11757.8 EKX44086.1 - 0.11 12.9 1.2 0.16 12.5 0.2 1.7 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain P4Ha_N PF08336.11 EKX44086.1 - 0.15 12.1 0.7 0.3 11.1 0.7 1.5 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region HgmA PF04209.13 EKX44087.1 - 9.5e-184 611.0 0.3 4e-182 605.7 0.3 2.0 1 1 0 1 1 1 1 homogentisate 1,2-dioxygenase DUF4205 PF13898.6 EKX44089.1 - 1.4e-64 218.3 0.1 1e-63 215.4 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4205) Cpn60_TCP1 PF00118.24 EKX44090.1 - 4.8e-156 520.2 6.4 5.4e-156 520.0 6.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Yae1_N PF09811.9 EKX44091.1 - 3.2e-05 23.5 5.5 0.00022 20.9 5.5 2.4 1 1 0 1 1 1 1 Essential protein Yae1, N terminal CAP59_mtransfer PF11735.8 EKX44092.1 - 1.2e-43 149.5 0.0 1.7e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 HEAT PF02985.22 EKX44095.1 - 0.12 12.7 2.6 0.23 11.8 0.1 2.9 3 0 0 3 3 3 0 HEAT repeat TP_methylase PF00590.20 EKX44096.1 - 3.5e-46 157.8 0.2 4.2e-46 157.6 0.2 1.1 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Glyco_transf_25 PF01755.17 EKX44097.1 - 0.0042 17.0 0.0 0.0075 16.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) RAP PF08373.10 EKX44098.1 - 2e-09 37.4 0.0 5.8e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 RAP domain DUF2482 PF10655.9 EKX44099.1 - 0.019 15.4 0.2 0.065 13.7 0.1 1.9 1 1 0 1 1 1 0 Hypothetical protein of unknown function (DUF2482) Sas10_Utp3 PF04000.15 EKX44100.1 - 9.1e-20 71.1 0.3 9.1e-20 71.1 0.3 2.0 2 1 0 2 2 2 1 Sas10/Utp3/C1D family ApoLp-III PF07464.11 EKX44100.1 - 0.003 17.7 1.8 0.0041 17.2 1.3 1.4 1 1 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) Uso1_p115_C PF04871.13 EKX44100.1 - 0.018 15.4 4.6 0.026 14.9 4.6 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region FAD_binding_2 PF00890.24 EKX44100.1 - 0.063 12.3 0.2 0.075 12.1 0.2 1.1 1 0 0 1 1 1 0 FAD binding domain YtxH PF12732.7 EKX44100.1 - 9.9 6.8 7.8 1.7e+02 2.8 7.8 2.2 1 1 0 1 1 1 0 YtxH-like protein Zip PF02535.22 EKX44101.1 - 1.4e-34 119.8 5.6 1.4e-34 119.8 5.6 2.1 2 1 0 2 2 2 1 ZIP Zinc transporter DUF4485 PF14846.6 EKX44102.1 - 0.012 15.7 0.3 0.034 14.2 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) Cobalamin_bind PF01122.19 EKX44102.1 - 0.014 14.3 1.9 0.038 12.9 0.8 2.1 2 0 0 2 2 2 0 Eukaryotic cobalamin-binding protein Pkinase PF00069.25 EKX44103.1 - 3.3e-51 174.2 0.0 6.7e-51 173.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain FHA PF00498.26 EKX44103.1 - 1e-24 86.6 0.6 2e-12 47.2 0.1 2.6 2 0 0 2 2 2 2 FHA domain Pkinase_Tyr PF07714.17 EKX44103.1 - 2.4e-22 79.5 0.0 3.7e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Yop-YscD_cpl PF16697.5 EKX44103.1 - 7e-15 55.1 0.5 2.2e-07 31.1 0.0 3.3 2 1 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain Kinase-like PF14531.6 EKX44103.1 - 8.1e-05 22.1 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EKX44103.1 - 0.0016 17.8 0.0 0.0038 16.6 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX44103.1 - 0.0027 17.7 0.1 0.0049 16.8 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EKX44103.1 - 0.0035 16.9 0.0 0.0071 15.9 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL FHA_2 PF17913.1 EKX44103.1 - 0.086 13.1 0.1 0.45 10.8 0.0 2.2 2 0 0 2 2 2 0 FHA domain DUF5011 PF16403.5 EKX44104.1 - 0.038 14.1 0.0 0.053 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5011) REJ PF02010.15 EKX44105.1 - 1.7e-16 60.1 0.5 7.2e-16 58.0 0.5 1.9 1 1 0 1 1 1 1 REJ domain PPDK_N PF01326.19 EKX44106.1 - 1.4e-22 80.4 0.0 6.9e-13 48.6 0.1 4.2 2 2 2 4 4 4 4 Pyruvate phosphate dikinase, PEP/pyruvate binding domain OppC_N PF12911.7 EKX44108.1 - 0.091 12.7 0.3 0.27 11.2 0.3 1.7 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C GYF PF02213.16 EKX44109.1 - 2.1e-08 33.7 0.7 8.8e-08 31.7 0.1 2.3 2 0 0 2 2 2 1 GYF domain Ish1 PF10281.9 EKX44109.1 - 7.2e-05 23.0 0.2 0.0084 16.4 0.1 3.3 3 0 0 3 3 3 1 Putative stress-responsive nuclear envelope protein Slx4 PF09494.10 EKX44109.1 - 0.094 12.7 0.0 0.43 10.6 0.0 2.2 2 0 0 2 2 2 0 Slx4 endonuclease GYF_2 PF14237.6 EKX44109.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 GYF domain 2 FMO-like PF00743.19 EKX44111.1 - 2.7e-18 65.7 0.0 1.4e-17 63.4 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EKX44111.1 - 1.9e-16 60.2 0.0 8.5e-08 31.8 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EKX44111.1 - 2.3e-11 43.4 0.0 6.9e-10 38.6 0.1 2.8 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EKX44111.1 - 7.1e-08 32.6 0.0 2.5e-07 30.8 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Wax2_C PF12076.8 EKX44111.1 - 1.3e-06 28.2 0.1 4.3e-06 26.6 0.1 1.9 1 0 0 1 1 1 1 WAX2 C-terminal domain Pyr_redox_2 PF07992.14 EKX44111.1 - 3.7e-05 23.1 0.0 0.00019 20.8 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EKX44111.1 - 0.00092 18.4 0.2 0.0021 17.2 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EKX44111.1 - 0.0023 18.5 0.1 3.5 8.3 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EKX44111.1 - 0.0034 17.4 0.0 0.034 14.1 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 EKX44111.1 - 0.0044 16.6 0.1 0.011 15.3 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EKX44111.1 - 0.0063 15.8 0.1 0.011 15.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EKX44111.1 - 0.0098 15.1 1.8 0.014 14.6 0.1 2.1 3 0 0 3 3 3 1 Thi4 family Shikimate_DH PF01488.20 EKX44111.1 - 0.01 15.9 0.1 8 6.5 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 EKX44111.1 - 0.031 13.0 0.0 0.059 12.1 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 EKX44111.1 - 0.033 13.3 0.4 0.054 12.6 0.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A MCRA PF06100.11 EKX44111.1 - 0.095 11.5 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 MCRA family ThiF PF00899.21 EKX44111.1 - 0.18 11.1 1.3 2.8 7.2 0.4 2.3 2 0 0 2 2 2 0 ThiF family SWIM PF04434.17 EKX44115.1 - 0.043 13.5 0.6 0.074 12.7 0.6 1.4 1 0 0 1 1 1 0 SWIM zinc finger DUF4880 PF16220.5 EKX44115.1 - 0.71 9.8 3.9 11 6.0 1.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4880) Phos_pyr_kin PF08543.12 EKX44116.1 - 8.5e-24 84.3 0.1 1.2e-23 83.8 0.1 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EKX44116.1 - 9.2e-12 44.9 0.0 2.5e-11 43.4 0.0 1.7 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 EKX44116.1 - 0.015 14.8 0.2 0.086 12.3 0.2 1.9 1 1 0 1 1 1 0 Carbohydrate kinase PDZ_2 PF13180.6 EKX44117.1 - 4.6e-05 23.7 0.1 7.6e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX44117.1 - 6.9e-05 23.1 0.1 0.00013 22.3 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX44117.1 - 0.00019 21.2 0.0 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX44117.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Tricorn protease PDZ domain EF-hand_1 PF00036.32 EKX44118.1 - 8.6e-24 81.3 6.5 1.1e-05 24.6 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EKX44118.1 - 2.7e-22 76.7 6.0 7.7e-06 25.4 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 EKX44118.1 - 4.3e-22 78.4 4.1 2.8e-12 46.9 0.2 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EKX44118.1 - 1.7e-17 63.0 9.6 1.8e-11 43.7 0.5 3.5 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EKX44118.1 - 1.3e-13 49.7 10.7 5.8e-05 22.4 0.0 5.1 5 0 0 5 5 5 4 EF hand Toprim_4 PF13662.6 EKX44118.1 - 0.0013 19.1 0.1 0.041 14.3 0.0 2.7 1 1 2 3 3 3 1 Toprim domain EF-hand_9 PF14658.6 EKX44118.1 - 0.0024 18.2 0.3 0.033 14.5 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_4 PF12763.7 EKX44118.1 - 0.0047 16.9 0.2 0.86 9.6 0.0 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Toprim_2 PF13155.6 EKX44118.1 - 0.018 15.5 0.0 0.39 11.2 0.0 2.4 1 1 1 2 2 2 0 Toprim-like SPARC_Ca_bdg PF10591.9 EKX44118.1 - 0.021 15.1 0.1 2.8 8.3 0.0 2.6 1 1 2 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region fn3 PF00041.21 EKX44119.1 - 1.7e-102 335.9 123.4 2.9e-07 30.7 0.1 35.0 35 2 0 35 35 35 22 Fibronectin type III domain LysM PF01476.20 EKX44119.1 - 1.4e-11 44.3 0.2 3.3e-07 30.3 0.0 3.3 3 0 0 3 3 3 2 LysM domain Pur_ac_phosph_N PF16656.5 EKX44119.1 - 3.7e-08 33.8 59.5 0.093 13.3 1.9 17.7 22 0 0 22 22 22 5 Purple acid Phosphatase, N-terminal domain F5_F8_type_C PF00754.25 EKX44119.1 - 0.018 15.2 3.7 0.14 12.3 0.4 4.2 3 0 0 3 3 3 0 F5/8 type C domain DUF2369 PF10179.9 EKX44119.1 - 0.028 14.8 15.8 4.1 7.9 0.1 7.9 9 0 0 9 9 9 0 Uncharacterised conserved protein (DUF2369) SusE PF14292.6 EKX44119.1 - 3.4 7.9 33.9 0.028 14.7 0.4 11.0 12 0 0 12 12 12 0 SusE outer membrane protein EBP50_C PF09007.11 EKX44120.1 - 0.0051 17.8 4.8 0.012 16.6 4.8 1.7 1 0 0 1 1 1 1 EBP50, C-terminal Miga PF10265.9 EKX44120.1 - 0.073 12.0 2.7 0.088 11.8 2.7 1.1 1 0 0 1 1 1 0 Mitoguardin MCM_bind PF09739.9 EKX44120.1 - 0.11 11.0 4.4 0.14 10.5 4.4 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor SR-25 PF10500.9 EKX44120.1 - 1 8.9 22.3 0.22 11.1 17.6 2.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Zincin_2 PF10103.9 EKX44122.1 - 0.081 12.2 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Zincin-like metallopeptidase PHD_2 PF13831.6 EKX44122.1 - 0.17 11.5 0.1 0.37 10.4 0.1 1.6 1 0 0 1 1 1 0 PHD-finger PNP_UDP_1 PF01048.20 EKX44123.1 - 1e-12 47.9 0.0 2.1e-12 46.8 0.0 1.4 1 1 0 1 1 1 1 Phosphorylase superfamily SET PF00856.28 EKX44125.1 - 6.2e-12 46.2 0.0 1.2e-11 45.3 0.0 1.5 1 0 0 1 1 1 1 SET domain PRTP PF01366.18 EKX44125.1 - 0.062 11.3 0.0 0.086 10.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein ANTH PF07651.16 EKX44126.1 - 3.4e-15 55.8 1.1 6.6e-15 54.8 1.1 1.4 1 1 0 1 1 1 1 ANTH domain ENTH PF01417.20 EKX44126.1 - 0.003 17.6 0.0 0.0073 16.4 0.0 1.6 1 0 0 1 1 1 1 ENTH domain TGFb_propeptide PF00688.18 EKX44127.1 - 0.011 15.5 0.8 0.02 14.6 0.8 1.5 1 1 0 1 1 1 0 TGF-beta propeptide P2_Phage_GpR PF06891.11 EKX44129.1 - 0.01 15.9 1.5 0.18 11.9 0.5 2.4 2 0 0 2 2 2 0 P2 phage tail completion protein R (GpR) DUF4419 PF14388.6 EKX44129.1 - 0.023 14.1 0.3 0.2 11.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4419) Herpes_UL52 PF03121.15 EKX44130.1 - 0.057 13.4 0.1 0.07 13.1 0.1 1.1 1 0 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase Clathrin_H_link PF13838.6 EKX44131.1 - 0.026 14.4 0.1 0.069 13.1 0.1 1.7 1 0 0 1 1 1 0 Clathrin-H-link YfdX PF10938.8 EKX44131.1 - 0.1 12.5 0.1 3.1 7.7 0.0 2.2 2 0 0 2 2 2 0 YfdX protein DUF3600 PF12207.8 EKX44131.1 - 0.12 12.3 0.1 0.27 11.2 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3600) DUF456 PF04306.13 EKX44132.1 - 0.029 14.7 3.6 0.039 14.2 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Bacteriocin_IIc PF10439.9 EKX44132.1 - 0.14 12.3 13.2 0.3 11.2 13.2 1.5 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_YMGG PF13441.6 EKX44132.1 - 0.63 9.8 17.8 1 9.2 17.8 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper Sel1 PF08238.12 EKX44135.1 - 7.8e-33 112.2 27.9 1.6e-10 41.3 0.3 8.1 8 0 0 8 8 8 7 Sel1 repeat Bacteriocin_IIc PF10439.9 EKX44136.1 - 0.016 15.3 2.0 0.02 15.0 2.0 1.2 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Cytochrom_B_N_2 PF13631.6 EKX44136.1 - 0.04 13.9 0.3 0.045 13.8 0.3 1.0 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB Abhydrolase_7 PF12715.7 EKX44136.1 - 0.14 11.4 0.1 0.16 11.2 0.1 1.1 1 0 0 1 1 1 0 Abhydrolase family Ammonium_transp PF00909.21 EKX44137.1 - 4.4e-23 81.6 3.1 5.8e-23 81.2 3.1 1.2 1 0 0 1 1 1 1 Ammonium Transporter Family INTS2 PF14750.6 EKX44139.1 - 4.7e-40 137.1 23.6 1.2e-29 102.6 5.6 4.8 4 1 0 4 4 4 4 Integrator complex subunit 2 eIF-3c_N PF05470.12 EKX44140.1 - 7.7e-143 476.9 72.2 1.5e-99 333.9 8.3 3.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EKX44140.1 - 1.8e-11 44.5 0.0 8.4e-11 42.3 0.0 2.2 2 0 0 2 2 2 1 PCI domain FAA_hydro_N_2 PF18288.1 EKX44140.1 - 0.023 15.1 0.0 0.086 13.3 0.0 2.0 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 DUF5097 PF17020.5 EKX44140.1 - 0.065 13.6 3.5 0.41 11.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5097) Ank_5 PF13857.6 EKX44141.1 - 5.2e-25 87.2 2.1 7.7e-09 35.6 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX44141.1 - 3.1e-22 78.6 5.7 4.3e-07 30.4 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX44141.1 - 4.5e-20 72.0 3.3 7.8e-13 48.8 0.8 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EKX44141.1 - 9.5e-17 60.6 4.4 0.00027 21.2 0.4 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EKX44141.1 - 1.8e-15 55.5 2.0 4.2e-05 23.6 0.1 3.7 4 0 0 4 4 4 3 Ankyrin repeat Pkinase PF00069.25 EKX44142.1 - 0.0051 16.2 0.0 0.0082 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX44142.1 - 0.029 13.7 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Kdo PF06293.14 EKX44142.1 - 0.034 13.5 0.1 0.068 12.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CheB_methylest PF01339.17 EKX44142.1 - 0.038 13.7 0.1 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 CheB methylesterase APH_6_hur PF04655.14 EKX44142.1 - 0.061 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase DUF4281 PF14108.6 EKX44143.1 - 3.4e-07 30.7 5.0 0.002 18.5 0.2 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4281) PAP_PilO PF06864.12 EKX44144.1 - 0.098 11.5 0.0 0.11 11.3 0.0 1.0 1 0 0 1 1 1 0 Pilin accessory protein (PilO) Nodulin_late PF07127.11 EKX44145.1 - 0.67 10.3 4.5 29 5.1 2.5 2.6 2 0 0 2 2 2 0 Late nodulin protein MFS_1 PF07690.16 EKX44146.1 - 0.0061 15.5 0.2 0.023 13.6 0.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily C2 PF00168.30 EKX44147.1 - 3e-21 75.6 0.0 1.5e-20 73.4 0.0 2.3 2 0 0 2 2 2 1 C2 domain PKD_channel PF08016.12 EKX44147.1 - 9.3e-21 74.0 33.9 1.6e-19 69.9 17.4 2.7 3 0 0 3 3 3 2 Polycystin cation channel Ion_trans PF00520.31 EKX44147.1 - 4.6e-11 42.4 29.6 1.8e-10 40.5 29.6 1.9 1 1 0 1 1 1 1 Ion transport protein ATP-synt_J PF04911.12 EKX44148.1 - 0.0024 17.4 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase j chain Zn-C2H2_12 PF18112.1 EKX44149.1 - 0.02 15.4 0.2 0.043 14.3 0.2 1.5 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain zf-ANAPC11 PF12861.7 EKX44149.1 - 0.028 14.5 0.5 0.34 11.0 0.1 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2H2_4 PF13894.6 EKX44149.1 - 0.073 14.0 2.0 5.4 8.1 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger BSP_II PF05432.11 EKX44150.1 - 0.0076 16.0 7.4 0.0076 16.0 7.4 3.3 3 0 0 3 3 3 1 Bone sialoprotein II (BSP-II) NCA2 PF08637.10 EKX44150.1 - 0.0086 15.3 0.2 0.025 13.8 0.2 1.7 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 PTPRCAP PF15713.5 EKX44150.1 - 5 7.4 53.5 3.7 7.8 18.4 3.5 3 0 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated TERB2 PF15101.6 EKX44150.1 - 5.2 7.1 8.4 16 5.5 8.4 1.8 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SET PF00856.28 EKX44151.1 - 7.9e-05 23.1 0.1 0.00011 22.6 0.1 1.3 1 0 0 1 1 1 1 SET domain Fer2_3 PF13085.6 EKX44151.1 - 0.67 10.0 2.7 1.5 8.9 2.7 1.7 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Toxin_25 PF08095.11 EKX44151.1 - 4 7.5 7.7 0.16 12.0 0.8 2.2 2 0 0 2 2 2 0 Hefutoxin family WD40 PF00400.32 EKX44152.1 - 8.3e-23 80.3 25.3 0.012 16.4 0.1 10.1 9 1 1 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX44152.1 - 0.0002 21.6 3.7 6.2 7.2 0.0 5.4 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EKX44152.1 - 0.0016 17.2 1.3 0.31 9.6 0.1 2.8 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EKX44152.1 - 0.18 10.5 1.2 9.3 4.9 0.0 2.8 4 0 0 4 4 4 0 Nup133 N terminal like Kelch_5 PF13854.6 EKX44153.1 - 2.1e-09 37.2 14.8 0.087 12.8 0.1 6.4 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 EKX44153.1 - 5.4e-07 29.7 12.1 0.0014 18.9 0.3 5.5 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 EKX44153.1 - 0.0016 18.0 8.9 1.4 8.6 0.0 4.9 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 EKX44153.1 - 0.012 15.5 9.7 0.019 14.9 1.2 3.9 4 0 0 4 4 4 0 Kelch motif Kelch_4 PF13418.6 EKX44153.1 - 0.031 14.3 17.9 0.15 12.1 0.2 5.3 5 0 0 5 5 5 0 Galactose oxidase, central domain Kelch_3 PF13415.6 EKX44153.1 - 0.075 13.3 33.7 0.11 12.9 0.2 7.8 8 0 0 8 8 8 0 Galactose oxidase, central domain BNR PF02012.20 EKX44153.1 - 0.076 13.1 4.4 5.5 7.4 0.2 3.7 2 0 0 2 2 2 0 BNR/Asp-box repeat zf-C2H2_2 PF12756.7 EKX44155.1 - 2.7e-16 59.8 0.8 2.8e-15 56.5 0.0 2.7 3 0 0 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EKX44155.1 - 0.018 15.4 0.0 0.018 15.4 0.0 2.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding DUF5624 PF18538.1 EKX44155.1 - 0.13 12.4 2.4 0.33 11.1 1.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5624) zf-C2H2 PF00096.26 EKX44155.1 - 1.2 9.7 3.4 1.1 9.8 0.5 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Peptidase_M49 PF03571.15 EKX44157.1 - 7.7e-121 404.1 0.3 1.5e-103 347.1 0.0 2.0 1 1 1 2 2 2 2 Peptidase family M49 CFC PF09443.10 EKX44157.1 - 0.44 10.4 1.6 3 7.8 0.1 2.5 2 0 0 2 2 2 0 Cripto_Frl-1_Cryptic (CFC) Myb_DNA-binding PF00249.31 EKX44158.1 - 1.7e-07 31.3 0.0 4e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 Myb-like DNA-binding domain RWP-RK PF02042.15 EKX44159.1 - 3.1e-11 43.1 0.0 4.7e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_24 PF13412.6 EKX44159.1 - 0.05 13.2 0.1 0.081 12.5 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF3235 PF11574.8 EKX44159.1 - 0.064 14.1 0.0 0.088 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) WRNPLPNID PF15017.6 EKX44159.1 - 0.19 12.6 4.3 0.16 12.9 2.6 1.8 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box tRNA-synt_2b PF00587.25 EKX44160.1 - 2.7e-29 102.4 0.0 5.9e-29 101.3 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EKX44160.1 - 8.7e-19 67.5 0.5 3.1e-18 65.7 0.8 1.8 2 0 0 2 2 2 1 Anticodon binding domain tRNA_SAD PF07973.14 EKX44160.1 - 8e-11 41.9 0.0 1.5e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 EKX44160.1 - 1.2e-06 28.4 0.0 5.9e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 TGS domain DUF892 PF05974.12 EKX44160.1 - 0.43 10.6 1.7 28 4.7 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF892) C2 PF00168.30 EKX44161.1 - 1e-21 77.1 0.0 1.9e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain Spc7 PF08317.11 EKX44161.1 - 0.0065 15.4 6.0 0.01 14.7 6.0 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein ERM PF00769.19 EKX44161.1 - 0.04 13.7 8.0 0.059 13.2 8.0 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DivIC PF04977.15 EKX44161.1 - 0.13 12.0 7.1 0.089 12.6 1.6 2.3 2 0 0 2 2 2 0 Septum formation initiator Atg14 PF10186.9 EKX44161.1 - 0.62 9.1 5.7 1.2 8.2 5.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF667 PF05018.13 EKX44162.1 - 1.8e-05 24.6 0.1 0.00011 22.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF667) KH_1 PF00013.29 EKX44163.1 - 8e-17 60.8 0.0 2.4e-13 49.7 0.0 2.2 2 0 0 2 2 2 2 KH domain SPRY PF00622.28 EKX44164.1 - 2.5e-10 40.5 0.0 6.4e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 SPRY domain ATG27 PF09451.10 EKX44165.1 - 1.7e-20 74.0 0.0 2.7e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 EKX44165.1 - 5.2e-10 38.8 0.0 1.1e-09 37.8 0.0 1.4 1 1 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.18 EKX44165.1 - 7.7e-08 32.5 0.4 5.5e-06 26.5 0.2 2.3 2 1 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat PRKCSH_1 PF13015.6 EKX44165.1 - 0.058 13.1 0.1 0.082 12.6 0.1 1.3 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein CxxCxxCC PF03692.15 EKX44166.1 - 8.1e-07 29.6 0.5 4.8e-06 27.2 0.5 2.1 1 1 0 1 1 1 1 Putative zinc- or iron-chelating domain Prot_inhib_II PF02428.15 EKX44166.1 - 0.098 13.1 2.3 0.098 13.1 0.5 1.9 3 0 0 3 3 3 0 Potato type II proteinase inhibitor family Pkinase_Tyr PF07714.17 EKX44167.1 - 1.2e-20 73.9 0.0 1.5e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX44167.1 - 3.7e-17 62.6 0.0 4.3e-17 62.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain PTH2 PF01981.16 EKX44169.1 - 2.6e-16 60.0 0.1 2.8e-16 59.8 0.1 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 RTC_insert PF05189.13 EKX44169.1 - 0.11 13.0 0.0 0.14 12.7 0.0 1.1 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase (RTC), insert domain CRAL_TRIO PF00650.20 EKX44170.1 - 9.9e-17 61.1 0.1 1.2e-16 60.8 0.1 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EKX44170.1 - 2.5e-08 34.2 0.0 3.1e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Spore_YhaL PF14147.6 EKX44170.1 - 0.2 11.4 0.4 1 9.1 0.2 2.0 2 0 0 2 2 2 0 Sporulation protein YhaL Sulfotransfer_1 PF00685.27 EKX44171.1 - 1.5e-11 44.3 0.1 3.4e-11 43.1 0.1 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_2 PF03567.14 EKX44171.1 - 6.6e-06 26.2 0.2 1.2e-05 25.4 0.2 1.5 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_3 PF13469.6 EKX44171.1 - 8.7e-05 23.0 0.2 1.4 9.3 0.1 3.1 2 1 1 3 3 3 2 Sulfotransferase family Beta_helix PF13229.6 EKX44172.1 - 1.1e-07 31.9 3.8 2.6e-07 30.6 3.8 1.6 1 0 0 1 1 1 1 Right handed beta helix region Chlam_PMP PF02415.17 EKX44172.1 - 0.04 14.4 27.9 0.97 10.1 0.0 6.7 7 0 0 7 7 7 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Laminin_EGF PF00053.24 EKX44172.1 - 1.2 9.3 15.5 0.88 9.8 1.3 3.3 2 0 0 2 2 2 0 Laminin EGF domain EGF_alliinase PF04863.13 EKX44172.1 - 1.3 9.5 30.1 1.6 9.2 7.8 3.8 2 1 1 3 3 3 0 Alliinase EGF-like domain EGF_2 PF07974.13 EKX44172.1 - 10 6.6 43.0 0.32 11.4 15.1 4.9 5 0 0 5 5 5 0 EGF-like domain Virulence_fact PF13769.6 EKX44173.1 - 9.2e-05 22.6 0.2 0.00025 21.2 0.2 1.7 1 0 0 1 1 1 1 Virulence factor RWP-RK PF02042.15 EKX44174.1 - 4.8e-11 42.4 0.4 8.9e-11 41.6 0.0 1.7 2 0 0 2 2 2 1 RWP-RK domain Aminotran_5 PF00266.19 EKX44175.1 - 8.1e-64 215.9 3.9 4.7e-55 187.0 0.1 2.6 1 1 2 3 3 3 2 Aminotransferase class-V Beta_elim_lyase PF01212.21 EKX44175.1 - 1.7e-10 40.7 0.3 2.1e-10 40.4 0.3 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EKX44175.1 - 4.4e-09 36.1 0.5 6.4e-09 35.6 0.5 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EKX44175.1 - 5.8e-06 25.1 0.1 7.9e-06 24.6 0.1 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.19 EKX44175.1 - 0.0038 16.0 0.2 0.011 14.5 0.2 1.7 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain BAH PF01426.18 EKX44177.1 - 7.1e-07 29.1 0.4 1.6e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 BAH domain Serglycin PF04360.12 EKX44178.1 - 0.0096 15.9 0.4 0.017 15.0 0.4 1.4 1 0 0 1 1 1 1 Serglycin Presenilin PF01080.17 EKX44179.1 - 0.0032 16.3 21.0 0.004 16.0 21.0 1.1 1 0 0 1 1 1 1 Presenilin PTPRCAP PF15713.5 EKX44179.1 - 0.0057 17.0 4.4 0.0082 16.4 4.4 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase receptor type C-associated ALMT PF11744.8 EKX44179.1 - 0.016 14.1 20.0 0.02 13.7 20.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter LAP1C PF05609.12 EKX44179.1 - 0.019 14.1 9.4 0.023 13.8 9.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF4551 PF15087.6 EKX44179.1 - 0.22 10.3 10.1 0.25 10.2 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CDC45 PF02724.14 EKX44179.1 - 0.27 9.5 11.7 0.33 9.2 11.7 1.0 1 0 0 1 1 1 0 CDC45-like protein RIFIN PF02009.16 EKX44179.1 - 0.28 11.0 11.3 0.34 10.8 11.3 1.0 1 0 0 1 1 1 0 Rifin SLC12 PF03522.15 EKX44179.1 - 0.32 10.0 23.2 0.37 9.8 23.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Zip PF02535.22 EKX44179.1 - 0.41 9.8 12.8 0.57 9.3 12.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BAF1_ABF1 PF04684.13 EKX44179.1 - 0.47 9.4 41.5 0.7 8.9 41.5 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Neur_chan_memb PF02932.16 EKX44179.1 - 0.72 9.9 8.5 1 9.4 8.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FAM60A PF15396.6 EKX44179.1 - 0.78 9.7 15.9 1 9.3 15.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A PNISR PF15996.5 EKX44179.1 - 0.83 9.9 15.5 1 9.6 15.5 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Raftlin PF15250.6 EKX44179.1 - 1.7 7.3 13.9 2 7.0 13.9 1.0 1 0 0 1 1 1 0 Raftlin DAG_kinase_N PF14513.6 EKX44179.1 - 1.9 8.7 15.3 4.8 7.4 15.3 1.6 1 1 0 1 1 1 0 Diacylglycerol kinase N-terminus ASD2 PF08687.11 EKX44179.1 - 3.4 7.1 13.2 4.3 6.8 13.2 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 MDFI PF15316.6 EKX44179.1 - 4.3 7.4 13.0 6.1 6.9 13.0 1.1 1 0 0 1 1 1 0 MyoD family inhibitor Hydin_ADK PF17213.3 EKX44179.1 - 4.7 7.5 6.6 6.1 7.1 6.6 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain NPR3 PF03666.13 EKX44179.1 - 6.1 5.5 28.8 8.1 5.1 28.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nop14 PF04147.12 EKX44179.1 - 7.4 4.7 17.2 8.9 4.4 17.2 1.0 1 0 0 1 1 1 0 Nop14-like family Kei1 PF08552.11 EKX44179.1 - 7.5 6.4 7.6 31 4.4 7.6 1.8 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Zn_clus PF00172.18 EKX44181.1 - 2.8e-06 27.3 6.2 2.8e-06 27.3 6.2 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ammonium_transp PF00909.21 EKX44183.1 - 1.6e-25 89.6 14.6 2.7e-25 88.9 14.6 1.3 1 0 0 1 1 1 1 Ammonium Transporter Family DSHCT PF08148.12 EKX44184.1 - 1.6e-31 109.2 0.0 4.5e-31 107.7 0.0 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 EKX44184.1 - 1.2e-19 70.7 0.0 3.2e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EKX44184.1 - 8.3e-11 42.2 0.0 1.8e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EKX44184.1 - 1.9e-05 25.0 0.0 5.4e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EKX44184.1 - 0.0018 18.6 0.2 0.0054 17.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 EKX44184.1 - 0.0047 16.0 0.1 0.022 13.8 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 EKX44184.1 - 0.011 15.4 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Tub_N PF16322.5 EKX44184.1 - 7.1 7.0 7.0 14 6.0 7.0 1.4 1 0 0 1 1 1 0 Tubby N-terminal RAP PF08373.10 EKX44186.1 - 1.5e-08 34.6 0.0 3.2e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 RAP domain FAM76 PF16046.5 EKX44188.1 - 1 8.7 7.1 1.3 8.4 7.1 1.2 1 0 0 1 1 1 0 FAM76 protein Zip PF02535.22 EKX44188.1 - 4.4 6.4 15.0 4.9 6.3 15.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CTU2 PF10288.9 EKX44189.1 - 0.013 15.7 0.8 0.037 14.3 0.8 1.7 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-CCCH PF00642.24 EKX44189.1 - 0.025 14.5 1.2 0.067 13.1 1.2 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EKX44189.1 - 0.13 12.3 1.5 0.35 11.0 1.5 1.8 1 0 0 1 1 1 0 Zinc finger domain DDE_Tnp_1_7 PF13843.6 EKX44190.1 - 6.6e-15 55.3 0.0 9.7e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Transposase IS4 AAA_12 PF13087.6 EKX44191.1 - 1.9e-30 106.0 0.1 1.9e-30 106.0 0.1 2.1 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 EKX44191.1 - 1.1e-26 94.2 14.9 1.1e-13 51.6 0.1 4.4 5 0 0 5 5 5 2 AAA domain AAA_30 PF13604.6 EKX44191.1 - 2.4e-10 40.5 0.0 5.2e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EKX44191.1 - 2.3e-07 31.3 0.0 1.7e-06 28.5 0.0 2.5 2 1 0 2 2 1 1 AAA domain CitMHS PF03600.16 EKX44191.1 - 0.00036 19.8 0.0 0.00038 19.7 0.0 1.2 1 0 0 1 1 1 1 Citrate transporter Viral_helicase1 PF01443.18 EKX44191.1 - 0.0018 18.1 0.7 0.36 10.5 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase PIF1 PF05970.14 EKX44191.1 - 0.0026 17.0 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 2 PIF1-like helicase Mak16 PF04874.14 EKX44191.1 - 0.0072 16.9 32.2 0.81 10.3 2.8 3.5 3 0 0 3 3 3 3 Mak16 protein C-terminal region UvrD-helicase PF00580.21 EKX44191.1 - 0.011 15.3 0.0 0.065 12.7 0.0 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain CPSF100_C PF13299.6 EKX44191.1 - 0.034 14.3 9.1 0.83 9.8 0.2 3.3 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal AAA_16 PF13191.6 EKX44191.1 - 0.036 14.4 2.6 0.045 14.1 0.1 2.3 1 1 1 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EKX44191.1 - 0.042 14.1 0.1 0.46 10.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Helicase_RecD PF05127.14 EKX44191.1 - 0.045 13.6 3.8 0.082 12.7 0.0 2.8 3 0 0 3 3 2 0 Helicase AAA PF00004.29 EKX44191.1 - 0.11 12.9 0.3 0.4 11.1 0.1 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Keratin_2_head PF16208.5 EKX44191.1 - 0.13 12.4 13.5 0.26 11.4 13.5 1.4 1 0 0 1 1 1 0 Keratin type II head RXT2_N PF08595.11 EKX44191.1 - 0.15 12.0 16.4 2.8 8.0 0.2 3.6 4 0 0 4 4 4 0 RXT2-like, N-terminal DUF4366 PF14283.6 EKX44191.1 - 0.35 10.9 10.0 1.3 9.1 5.7 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) ResIII PF04851.15 EKX44191.1 - 0.7 9.9 5.4 1.2 9.1 0.0 3.5 4 1 0 4 4 3 0 Type III restriction enzyme, res subunit Thg1C PF14413.6 EKX44191.1 - 0.87 9.8 4.5 27 5.0 0.4 3.0 3 0 0 3 3 3 0 Thg1 C terminal domain FYDLN_acid PF09538.10 EKX44191.1 - 1.3 9.7 22.5 5.6 7.7 0.5 3.4 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) RNA_pol_Rpc4 PF05132.14 EKX44191.1 - 1.7 9.1 11.3 9.7 6.6 1.8 3.2 3 0 0 3 3 3 0 RNA polymerase III RPC4 PAXIP1_C PF15364.6 EKX44191.1 - 4.8 7.5 23.8 2.5 8.4 1.0 3.4 3 0 0 3 3 3 0 PAXIP1-associated-protein-1 C term PTIP binding protein DUF2625 PF10946.8 EKX44192.1 - 0.33 10.0 2.2 1 8.4 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF2625 C2 PF00168.30 EKX44193.1 - 3e-16 59.6 0.0 4.8e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 C2 domain PAP_fibrillin PF04755.12 EKX44195.1 - 4.9e-11 42.9 0.0 7e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 PAP_fibrillin DAHP_synth_1 PF00793.20 EKX44197.1 - 6.6e-80 267.9 0.3 8.1e-80 267.6 0.3 1.0 1 0 0 1 1 1 1 DAHP synthetase I family PAS_9 PF13426.7 EKX44199.1 - 4.5e-10 39.7 0.0 4.7e-10 39.7 0.0 1.0 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EKX44199.1 - 0.015 15.3 0.0 0.017 15.1 0.0 1.1 1 0 0 1 1 1 0 PAS fold PAS_4 PF08448.10 EKX44199.1 - 0.047 13.9 0.0 0.053 13.8 0.0 1.1 1 0 0 1 1 1 0 PAS fold PAS_3 PF08447.12 EKX44199.1 - 0.058 13.7 0.0 0.063 13.6 0.0 1.2 1 0 0 1 1 1 0 PAS fold Glyco_transf_41 PF13844.6 EKX44200.1 - 4e-58 197.0 0.0 5.7e-30 104.2 0.0 2.3 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_2 PF07719.17 EKX44200.1 - 9.7e-34 112.8 19.1 0.00044 20.1 0.0 11.6 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_11 PF13414.6 EKX44200.1 - 1.3e-30 104.8 4.3 2.9e-09 36.5 0.0 7.6 6 1 1 7 7 7 5 TPR repeat TPR_1 PF00515.28 EKX44200.1 - 2.9e-26 90.2 15.1 0.0065 16.2 0.0 11.3 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_16 PF13432.6 EKX44200.1 - 6.3e-26 90.7 19.0 6.1e-08 33.2 0.1 7.3 5 2 2 7 7 7 7 Tetratricopeptide repeat TPR_8 PF13181.6 EKX44200.1 - 2.3e-25 86.6 15.4 0.0045 17.1 0.0 11.2 11 1 0 11 11 10 6 Tetratricopeptide repeat TPR_14 PF13428.6 EKX44200.1 - 6e-25 85.8 15.0 0.015 16.1 0.5 10.4 4 2 6 10 10 10 8 Tetratricopeptide repeat TPR_19 PF14559.6 EKX44200.1 - 2.7e-24 85.5 9.7 5.5e-08 33.2 0.3 7.5 4 2 4 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.6 EKX44200.1 - 3e-20 71.1 10.3 3.9e-05 23.7 0.1 8.8 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 EKX44200.1 - 2.2e-15 56.7 20.1 1.1e-05 25.7 0.5 7.7 2 2 7 9 9 9 7 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX44200.1 - 4.8e-12 45.9 12.9 3.7e-07 30.3 2.2 5.3 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EKX44200.1 - 2.2e-11 43.2 23.1 0.32 10.9 0.1 10.0 10 1 0 10 10 10 3 Tetratricopeptide repeat TPR_9 PF13371.6 EKX44200.1 - 5.6e-10 39.2 8.4 0.0015 18.6 0.2 6.5 4 3 2 6 6 6 3 Tetratricopeptide repeat NARP1 PF12569.8 EKX44200.1 - 1.1e-08 34.5 5.1 0.0032 16.5 0.2 3.8 3 1 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 EKX44200.1 - 6.9e-07 29.5 19.0 2 9.2 0.1 9.2 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX44200.1 - 8e-07 28.7 13.7 1.9 8.7 0.1 9.7 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_4 PF07721.14 EKX44200.1 - 1.2e-06 28.6 10.2 3 8.7 0.0 8.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 EKX44200.1 - 3.8e-06 26.3 10.9 0.24 10.6 0.6 4.7 2 1 2 4 4 4 3 Tetratricopeptide repeat FAT PF02259.23 EKX44200.1 - 0.002 17.4 1.7 0.21 10.8 1.0 2.9 1 1 1 2 2 2 1 FAT domain DUF3856 PF12968.7 EKX44200.1 - 0.0063 16.6 1.4 9 6.4 0.0 4.6 3 1 1 5 5 4 0 Domain of Unknown Function (DUF3856) TPR_20 PF14561.6 EKX44200.1 - 0.02 15.2 6.2 1.1 9.7 0.1 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat BTAD PF03704.17 EKX44200.1 - 0.029 14.8 16.3 0.32 11.4 0.1 4.8 2 1 3 5 5 5 0 Bacterial transcriptional activator domain HrpB1_HrpK PF09613.10 EKX44200.1 - 0.14 11.8 1.6 13 5.4 0.1 2.8 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) RL10P_insert PF17777.1 EKX44202.1 - 9e-18 64.1 0.3 2.1e-17 62.9 0.3 1.6 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 EKX44202.1 - 1.4e-17 64.1 8.4 1.6e-17 63.9 5.0 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein Ribosomal_L10 PF00466.20 EKX44202.1 - 6.4e-16 58.3 1.2 1.4e-15 57.2 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L10 Peptidase_M41 PF01434.18 EKX44204.1 - 0.007 16.2 1.1 0.13 12.1 1.0 2.8 2 1 0 2 2 2 1 Peptidase family M41 V_ATPase_I PF01496.19 EKX44204.1 - 0.56 8.1 4.5 0.63 7.9 3.7 1.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family SMC_N PF02463.19 EKX44205.1 - 9.7e-57 191.9 46.8 1.1e-55 188.4 46.8 3.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EKX44205.1 - 2.3e-22 79.5 0.6 6.9e-22 78.0 0.6 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EKX44205.1 - 7.7e-11 42.3 0.5 0.00032 20.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EKX44205.1 - 3.1e-08 34.4 27.5 3.1e-08 34.4 27.5 7.0 2 2 3 5 5 5 1 AAA domain AAA_29 PF13555.6 EKX44205.1 - 0.00074 19.2 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 EKX44205.1 - 0.0061 17.1 0.0 0.0061 17.1 0.0 5.8 4 3 0 5 5 5 2 ABC transporter FliJ PF02050.16 EKX44205.1 - 0.01 16.0 7.1 0.01 16.0 7.1 8.2 4 2 4 8 8 8 0 Flagellar FliJ protein LacI PF00356.21 EKX44205.1 - 1.7 8.5 5.9 4.9 7.0 0.0 3.5 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family Herpes_UL92 PF03048.14 EKX44205.1 - 3.2 7.5 5.6 5.5 6.7 0.4 3.2 2 0 0 2 2 2 0 UL92 family MscS_TM PF12794.7 EKX44205.1 - 6.3 5.6 7.4 19 4.0 7.4 1.8 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Branch PF02485.21 EKX44206.1 - 4e-29 101.9 0.0 9e-29 100.7 0.0 1.5 1 1 0 1 1 1 1 Core-2/I-Branching enzyme Kinetochor_Ybp2 PF08568.10 EKX44207.1 - 0.016 13.7 0.0 0.063 11.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family, YAP/Alf4/glomulin DUF3848 PF12959.7 EKX44207.1 - 0.22 11.6 1.2 35 4.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3848) Zn_clus PF00172.18 EKX44209.1 - 2.7e-06 27.4 6.6 2.7e-06 27.4 6.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PDZ_6 PF17820.1 EKX44211.1 - 6.2e-17 61.2 5.2 4.7e-12 45.6 0.4 3.6 3 1 0 3 3 3 2 PDZ domain PDZ PF00595.24 EKX44211.1 - 5.8e-11 42.6 4.5 4.4e-09 36.6 0.3 2.9 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 EKX44211.1 - 2.5e-10 40.5 1.5 2.9e-05 24.3 0.1 2.7 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 EKX44211.1 - 2.8e-05 24.0 1.1 0.19 11.7 0.1 2.7 2 0 0 2 2 2 2 Tricorn protease PDZ domain DUF3394 PF11874.8 EKX44211.1 - 0.015 15.0 0.1 4.9 6.8 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3394) Glutaredoxin PF00462.24 EKX44212.1 - 1.5e-18 66.8 0.0 1.9e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin SH3BGR PF04908.15 EKX44212.1 - 0.045 13.9 0.0 0.063 13.4 0.0 1.4 1 1 0 1 1 1 0 SH3-binding, glutamic acid-rich protein BolA PF01722.18 EKX44213.1 - 1.6e-16 60.3 0.0 2.3e-16 59.9 0.0 1.3 1 1 0 1 1 1 1 BolA-like protein Pkinase PF00069.25 EKX44214.1 - 3.1e-23 82.5 0.1 4.7e-13 49.1 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EKX44214.1 - 7.7e-10 38.5 0.5 6.1e-05 22.4 0.1 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EKX44214.1 - 0.059 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like O-FucT PF10250.9 EKX44215.1 - 0.041 13.6 0.0 0.46 10.1 0.0 1.9 2 0 0 2 2 2 0 GDP-fucose protein O-fucosyltransferase Nop14 PF04147.12 EKX44216.1 - 2.8e-150 502.4 45.3 7e-150 501.0 45.3 1.5 1 1 0 1 1 1 1 Nop14-like family FAM221 PF14753.6 EKX44216.1 - 0.068 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein FAM221A/B ubiquitin PF00240.23 EKX44217.1 - 7.9e-06 25.5 0.0 9e-06 25.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EKX44217.1 - 0.031 14.1 0.0 0.037 13.9 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like BAH PF01426.18 EKX44218.1 - 1.3e-11 44.4 0.0 1.7e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 BAH domain ID PF18543.1 EKX44218.1 - 0.12 12.4 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 Intracellular delivery domain BAH PF01426.18 EKX44219.1 - 8.2e-08 32.1 0.1 1.4e-07 31.4 0.1 1.3 1 1 0 1 1 1 1 BAH domain RPN6_N PF18055.1 EKX44220.1 - 3.5e-39 133.8 0.4 3.5e-39 133.8 0.4 2.8 3 1 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 EKX44220.1 - 3.8e-13 49.9 1.5 1.2e-12 48.2 0.3 2.6 3 1 0 3 3 3 1 PCI domain RPN6_C_helix PF18503.1 EKX44220.1 - 1.8e-10 40.4 1.2 3.5e-10 39.4 0.2 2.1 2 0 0 2 2 2 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_12 PF13424.6 EKX44220.1 - 4.3e-08 33.3 4.4 2e-05 24.8 0.2 4.2 5 0 0 5 5 4 1 Tetratricopeptide repeat DUF410 PF04190.13 EKX44220.1 - 0.014 15.3 0.3 0.14 12.0 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF410) TPR_19 PF14559.6 EKX44220.1 - 0.027 15.0 2.7 0.88 10.1 0.0 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX44220.1 - 0.03 13.7 1.2 0.063 12.6 0.8 1.7 1 1 1 2 2 2 0 MalT-like TPR region TPR_14 PF13428.6 EKX44220.1 - 0.044 14.6 0.8 40 5.4 0.0 4.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EKX44220.1 - 0.05 13.4 7.1 2.2 8.2 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF627 PF04781.12 EKX44220.1 - 0.053 13.5 0.3 0.78 9.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF627) TPR_2 PF07719.17 EKX44220.1 - 0.055 13.6 7.3 0.84 9.9 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX44220.1 - 0.06 13.6 3.8 5.4 7.5 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EKX44220.1 - 0.074 13.1 7.8 11 6.3 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX44220.1 - 0.084 12.8 1.0 1.6 8.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EKX44220.1 - 0.13 12.9 2.8 2.1 9.1 0.0 3.9 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 EKX44220.1 - 0.82 9.4 4.9 1.3 8.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain EF-hand_5 PF13202.6 EKX44221.1 - 4.8e-14 51.1 9.0 0.003 17.0 0.0 6.3 6 0 0 6 6 6 4 EF hand EF-hand_1 PF00036.32 EKX44221.1 - 4.6e-13 47.7 8.0 0.017 14.7 0.0 6.4 5 1 1 6 6 6 4 EF hand EF-hand_7 PF13499.6 EKX44221.1 - 5.4e-12 46.0 0.1 0.048 14.1 0.0 4.9 2 1 2 4 4 4 3 EF-hand domain pair Ion_trans_2 PF07885.16 EKX44221.1 - 7.2e-12 45.1 5.7 1.5e-11 44.1 5.1 1.8 1 1 0 1 1 1 1 Ion channel EF-hand_6 PF13405.6 EKX44221.1 - 2.1e-09 36.6 8.2 0.22 11.6 0.0 6.1 4 2 2 6 6 6 3 EF-hand domain EF-hand_8 PF13833.6 EKX44221.1 - 4.6e-09 36.0 0.9 0.012 15.4 0.0 4.5 3 1 1 4 4 4 3 EF-hand domain pair Lig_chan PF00060.26 EKX44221.1 - 1.6e-07 31.3 0.0 7.9e-07 29.0 0.0 2.0 1 1 1 2 2 2 1 Ligand-gated ion channel Caleosin PF05042.13 EKX44221.1 - 0.12 12.3 0.0 4 7.4 0.0 2.9 3 0 0 3 3 3 0 Caleosin related protein IRK PF01007.20 EKX44221.1 - 0.12 12.2 3.5 0.59 9.9 1.6 2.2 1 1 1 2 2 2 0 Inward rectifier potassium channel transmembrane domain Ion_trans PF00520.31 EKX44221.1 - 0.13 11.5 4.5 0.23 10.6 4.5 1.3 1 0 0 1 1 1 0 Ion transport protein ABC_tran PF00005.27 EKX44222.1 - 1.6e-06 28.7 0.1 9.4e-06 26.2 0.1 2.0 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EKX44222.1 - 0.0091 15.4 0.2 0.66 9.4 0.1 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 EKX44222.1 - 0.031 13.4 0.1 0.042 12.9 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Dynamin_N PF00350.23 EKX44222.1 - 0.076 13.1 0.2 0.12 12.4 0.2 1.3 1 0 0 1 1 1 0 Dynamin family AAA_29 PF13555.6 EKX44222.1 - 0.18 11.6 0.3 0.46 10.3 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Methyltransf_21 PF05050.12 EKX44224.1 - 5.4e-12 46.1 0.0 1.2e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase FkbM domain FAD-oxidase_C PF02913.19 EKX44225.1 - 2.6e-52 178.0 0.0 3.5e-52 177.5 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EKX44225.1 - 2.7e-37 127.6 0.2 1.3e-36 125.4 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain cNMP_binding PF00027.29 EKX44226.1 - 3.1e-18 65.6 0.0 3.5e-18 65.5 0.0 1.0 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Nucleoside_tran PF01733.18 EKX44227.1 - 1.1e-36 126.9 0.1 1.8e-36 126.1 0.1 1.3 1 0 0 1 1 1 1 Nucleoside transporter TLE_N PF03920.15 EKX44229.1 - 0.032 14.3 0.2 5.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Groucho/TLE N-terminal Q-rich domain Roc PF08477.13 EKX44231.1 - 4.9e-12 46.1 0.0 7.8e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EKX44231.1 - 4.7e-08 32.8 0.0 6.4e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Ras family Arf PF00025.21 EKX44231.1 - 1.3e-05 24.7 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EKX44231.1 - 0.00065 19.1 0.0 0.001 18.5 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EKX44231.1 - 0.0017 18.4 0.0 0.003 17.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EKX44231.1 - 0.0034 16.6 0.0 1 8.4 0.1 2.3 1 1 0 2 2 2 2 G-protein alpha subunit Dynamin_N PF00350.23 EKX44231.1 - 0.036 14.1 0.1 0.041 13.9 0.1 1.5 1 1 0 1 1 1 0 Dynamin family AAA_28 PF13521.6 EKX44231.1 - 0.081 13.2 0.1 0.16 12.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EKX44231.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain Ammonium_transp PF00909.21 EKX44232.1 - 4.4e-28 98.1 13.2 4.4e-28 98.1 13.2 2.1 2 0 0 2 2 2 2 Ammonium Transporter Family Cu-oxidase_2 PF07731.14 EKX44234.1 - 0.064 13.0 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Multicopper oxidase Dynamin_N PF00350.23 EKX44238.1 - 3.4e-08 33.7 4.8 4.5e-08 33.3 0.2 3.0 2 1 1 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 EKX44238.1 - 1.4e-05 25.2 0.0 5.2e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EKX44238.1 - 0.0093 15.3 0.5 2.9 7.2 0.1 2.7 2 0 0 2 2 2 2 AIG1 family Roc PF08477.13 EKX44238.1 - 0.012 15.9 0.0 0.12 12.6 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PspB PF06667.12 EKX44238.1 - 0.18 11.9 1.9 0.95 9.6 0.1 2.7 2 0 0 2 2 2 0 Phage shock protein B Apolipoprotein PF01442.18 EKX44238.1 - 0.23 11.3 3.2 9.6 6.0 0.1 2.5 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain T6PP_N PF18572.1 EKX44238.1 - 4.5 7.2 6.6 1.2 9.0 1.2 2.4 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain SGL PF08450.12 EKX44239.1 - 2.3e-55 187.8 0.4 1.3e-53 182.2 0.4 2.0 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 EKX44239.1 - 0.00011 22.0 0.4 0.071 13.4 0.0 3.4 2 0 0 2 2 2 2 Two component regulator propeller PQQ PF01011.21 EKX44239.1 - 0.031 14.2 0.0 11 6.2 0.0 3.0 3 0 0 3 3 3 0 PQQ enzyme repeat TrkH PF02386.16 EKX44240.1 - 6.3e-53 180.0 13.5 1.5e-50 172.1 4.7 2.1 2 0 0 2 2 2 2 Cation transport protein Tctex-1 PF03645.13 EKX44241.1 - 1.3e-27 96.0 0.1 1.7e-27 95.7 0.1 1.1 1 0 0 1 1 1 1 Tctex-1 family CCT_2 PF09425.10 EKX44242.1 - 0.25 11.2 0.5 0.44 10.5 0.5 1.4 1 0 0 1 1 1 0 Divergent CCT motif RNase_H PF00075.24 EKX44243.1 - 0.16 12.1 0.0 0.18 12.0 0.0 1.1 1 0 0 1 1 1 0 RNase H CCT_2 PF09425.10 EKX44244.1 - 0.25 11.2 0.5 0.44 10.5 0.5 1.4 1 0 0 1 1 1 0 Divergent CCT motif CCT_2 PF09425.10 EKX44246.1 - 0.22 11.5 0.5 0.44 10.5 0.5 1.5 1 0 0 1 1 1 0 Divergent CCT motif RNase_H PF00075.24 EKX44247.1 - 0.16 12.1 0.0 0.18 12.0 0.0 1.1 1 0 0 1 1 1 0 RNase H CCT_2 PF09425.10 EKX44248.1 - 0.25 11.3 0.5 0.44 10.5 0.5 1.4 1 0 0 1 1 1 0 Divergent CCT motif AAA_11 PF13086.6 EKX44249.1 - 6.7e-06 26.1 6.9 9.7e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EKX44249.1 - 0.00089 19.0 0.3 0.0022 17.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA PF00004.29 EKX44249.1 - 0.0035 17.8 1.3 0.0099 16.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EKX44249.1 - 0.0063 16.1 0.1 0.028 14.0 0.0 2.1 2 1 0 2 2 1 1 AAA domain FapA PF03961.13 EKX44249.1 - 0.011 14.4 4.3 0.016 13.9 4.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A AAA_24 PF13479.6 EKX44249.1 - 0.014 15.1 0.2 0.35 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain COG5 PF10392.9 EKX44249.1 - 0.017 15.3 1.7 0.036 14.2 1.7 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 IstB_IS21 PF01695.17 EKX44249.1 - 0.019 14.7 0.1 0.074 12.8 0.0 2.0 3 0 0 3 3 1 0 IstB-like ATP binding protein Golgin_A5 PF09787.9 EKX44249.1 - 0.027 13.9 11.9 0.042 13.3 11.9 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 AAA_7 PF12775.7 EKX44249.1 - 0.029 13.9 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Laminin_II PF06009.12 EKX44249.1 - 0.057 13.4 8.9 0.13 12.3 8.9 1.5 1 0 0 1 1 1 0 Laminin Domain II AAA_18 PF13238.6 EKX44249.1 - 0.078 13.5 0.8 0.36 11.4 0.0 2.5 3 0 0 3 3 1 0 AAA domain Ferritin PF00210.24 EKX44249.1 - 0.08 12.9 3.6 0.18 11.7 3.6 1.5 1 0 0 1 1 1 0 Ferritin-like domain GrpE PF01025.19 EKX44249.1 - 0.091 12.4 7.4 0.23 11.1 7.4 1.8 1 0 0 1 1 1 0 GrpE CbiA PF01656.23 EKX44249.1 - 0.13 12.3 0.1 0.28 11.3 0.0 1.7 2 0 0 2 2 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain FtsQ PF03799.15 EKX44249.1 - 0.17 12.7 0.9 0.41 11.5 0.9 1.6 1 0 0 1 1 1 0 Cell division protein FtsQ Exonuc_VII_L PF02601.15 EKX44249.1 - 0.18 11.3 5.6 0.32 10.5 3.9 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit TMPIT PF07851.13 EKX44249.1 - 0.19 11.0 5.4 0.32 10.2 5.4 1.3 1 0 0 1 1 1 0 TMPIT-like protein GAS PF13851.6 EKX44249.1 - 0.19 11.1 14.9 0.34 10.2 14.9 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 EKX44249.1 - 0.26 11.5 9.4 0.5 10.5 9.0 1.6 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family Spc7 PF08317.11 EKX44249.1 - 0.29 10.0 13.1 0.46 9.3 13.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein ResIII PF04851.15 EKX44249.1 - 0.3 11.1 3.6 2.5 8.1 0.0 2.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 EKX44249.1 - 0.34 11.4 2.9 3.1 8.3 0.0 2.5 2 1 0 2 2 2 0 ABC transporter LMBR1 PF04791.16 EKX44249.1 - 0.37 9.6 2.7 0.56 9.1 2.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein She9_MDM33 PF05546.11 EKX44249.1 - 0.4 10.5 8.4 0.67 9.7 8.4 1.3 1 0 0 1 1 1 0 She9 / Mdm33 family Syntaxin_2 PF14523.6 EKX44249.1 - 0.42 11.0 9.9 0.99 9.8 9.9 1.6 1 0 0 1 1 1 0 Syntaxin-like protein AAA_22 PF13401.6 EKX44249.1 - 0.44 10.8 3.1 0.5 10.6 0.1 2.4 2 1 0 2 2 2 0 AAA domain Tho2 PF11262.8 EKX44249.1 - 0.5 9.5 4.7 0.81 8.8 4.7 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF4407 PF14362.6 EKX44249.1 - 0.54 9.6 4.3 0.86 8.9 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF812 PF05667.11 EKX44249.1 - 0.7 8.7 12.1 1 8.2 12.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF948 PF06103.11 EKX44249.1 - 0.8 10.0 4.6 1.9 8.8 3.9 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Cortex-I_coil PF09304.10 EKX44249.1 - 1.1 9.5 11.1 1.1 9.5 9.4 1.8 1 1 1 2 2 2 0 Cortexillin I, coiled coil Phage_GP20 PF06810.11 EKX44249.1 - 1.3 8.8 11.4 2.7 7.8 0.8 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 KxDL PF10241.9 EKX44249.1 - 1.6 9.1 6.4 1.3 9.3 4.2 2.0 2 0 0 2 2 1 0 Uncharacterized conserved protein Seryl_tRNA_N PF02403.22 EKX44249.1 - 2.4 8.4 11.0 6 7.1 10.8 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ZapB PF06005.12 EKX44249.1 - 2.6 8.6 16.4 0.79 10.2 9.1 2.4 2 0 0 2 2 2 0 Cell division protein ZapB CP12 PF02672.15 EKX44249.1 - 2.9 8.7 5.4 8 7.3 5.4 1.7 1 0 0 1 1 1 0 CP12 domain Methyltrans_Mon PF14314.6 EKX44249.1 - 3.2 5.7 5.8 3.2 5.7 4.6 1.5 1 1 1 2 2 2 0 Virus-capping methyltransferase APG17 PF04108.12 EKX44249.1 - 3.7 6.6 10.7 6.1 5.9 10.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 Atg14 PF10186.9 EKX44249.1 - 4.1 6.4 7.8 7.2 5.6 7.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3450 PF11932.8 EKX44249.1 - 4.4 6.5 11.4 7.6 5.8 11.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) HisKA_3 PF07730.13 EKX44249.1 - 4.5 7.9 7.7 1.2 9.7 1.1 3.0 3 0 0 3 3 3 0 Histidine kinase DUF1664 PF07889.12 EKX44249.1 - 4.7 7.3 8.9 14 5.7 8.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4715 PF15835.5 EKX44249.1 - 5.3 7.1 11.4 23 5.1 10.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4715) COG2 PF06148.11 EKX44249.1 - 6.4 6.9 7.9 15 5.7 7.5 1.8 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 IFT57 PF10498.9 EKX44249.1 - 7.2 5.5 13.4 60 2.4 13.5 2.0 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 YabA PF06156.13 EKX44249.1 - 9.4 6.9 11.6 54 4.5 11.6 2.2 1 1 0 1 1 1 0 Initiation control protein YabA Ank_2 PF12796.7 EKX44252.1 - 3e-09 37.3 0.1 4.7e-09 36.7 0.1 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX44252.1 - 1.4e-08 35.1 0.1 6.4e-06 26.6 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX44252.1 - 1.8e-06 28.1 0.0 2.5e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX44252.1 - 3.6e-06 27.2 0.0 0.00017 21.9 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EKX44252.1 - 1.8e-05 24.8 0.0 0.0061 17.0 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat RCC1 PF00415.18 EKX44253.1 - 5.1e-23 81.4 0.8 3.6e-07 30.7 0.1 3.4 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX44253.1 - 7.3e-16 57.5 4.8 5.4e-09 35.6 0.3 3.0 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Lectin_legB PF00139.19 EKX44253.1 - 6.6e-05 22.6 0.2 0.00011 21.9 0.2 1.2 1 0 0 1 1 1 1 Legume lectin domain SH3_5 PF08460.10 EKX44253.1 - 0.13 12.3 0.3 0.31 11.2 0.3 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain RCC1 PF00415.18 EKX44254.1 - 4.8e-13 49.5 0.1 1.6e-05 25.5 0.0 2.6 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX44254.1 - 0.028 14.2 0.2 0.38 10.6 0.1 2.3 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat EF-hand_7 PF13499.6 EKX44255.1 - 8e-16 58.3 0.4 8.7e-11 42.1 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX44255.1 - 4.7e-14 51.0 0.5 0.0037 17.1 0.1 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 EKX44255.1 - 5.2e-14 50.7 0.2 2.8e-05 23.3 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EKX44255.1 - 3.5e-08 33.2 0.7 5e-06 26.3 0.2 2.7 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX44255.1 - 1.3e-06 27.6 0.4 0.00051 19.4 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 EKX44255.1 - 0.00091 19.5 0.1 0.28 11.5 0.0 2.6 2 1 1 3 3 3 2 EF-hand domain Dockerin_1 PF00404.18 EKX44255.1 - 0.021 15.0 0.3 0.15 12.3 0.5 2.3 2 1 0 2 2 2 0 Dockerin type I domain Oxysterol_BP PF01237.18 EKX44256.1 - 5.2e-37 127.6 2.8 1.2e-26 93.4 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein Cyclin PF08613.11 EKX44257.1 - 2.5e-36 125.5 1.1 2.8e-36 125.3 1.1 1.0 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EKX44257.1 - 4.1e-08 33.0 0.1 5.2e-08 32.7 0.1 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Zmiz1_N PF18028.1 EKX44260.1 - 0.022 15.1 0.1 0.035 14.4 0.1 1.5 1 1 0 1 1 1 0 Zmiz1 N-terminal tetratricopeptide repeat domain Aminotran_4 PF01063.19 EKX44262.1 - 2e-37 129.2 0.0 2.3e-37 129.0 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV 6PF2K PF01591.18 EKX44263.1 - 7e-47 159.6 0.1 1.5e-26 93.1 0.0 2.1 1 1 1 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EKX44263.1 - 3e-06 27.1 0.0 7.2e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SDA1 PF05285.12 EKX44263.1 - 0.00057 19.4 12.0 0.00068 19.2 12.0 1.2 1 0 0 1 1 1 1 SDA1 OKR_DC_1_N PF03709.15 EKX44263.1 - 0.00095 19.4 0.3 0.0017 18.6 0.3 1.3 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain CDC45 PF02724.14 EKX44263.1 - 0.0017 16.8 11.4 0.002 16.5 11.4 1.1 1 0 0 1 1 1 1 CDC45-like protein AAA_18 PF13238.6 EKX44263.1 - 0.0065 17.0 1.8 0.024 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 EKX44263.1 - 0.0067 15.9 0.0 0.015 14.8 0.0 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EKX44263.1 - 0.019 15.2 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EKX44263.1 - 0.027 14.5 0.1 0.054 13.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain Connexin PF00029.19 EKX44263.1 - 0.067 12.9 0.1 0.097 12.4 0.1 1.2 1 0 0 1 1 1 0 Connexin NOA36 PF06524.12 EKX44263.1 - 0.92 8.8 23.1 1.7 7.9 23.1 1.5 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 EKX44263.1 - 4.6 5.3 24.4 6.1 4.9 24.4 1.2 1 0 0 1 1 1 0 Nop14-like family Astro_capsid_p PF12226.8 EKX44263.1 - 5 6.2 14.7 10 5.1 14.7 1.6 1 0 0 1 1 1 0 Turkey astrovirus capsid protein GGACT PF06094.12 EKX44264.1 - 2.5e-07 31.3 0.0 0.0011 19.6 0.0 2.2 2 0 0 2 2 2 2 Gamma-glutamyl cyclotransferase, AIG2-like ChaC PF04752.12 EKX44264.1 - 0.012 15.7 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 ChaC-like protein NOA36 PF06524.12 EKX44265.1 - 0.045 13.1 4.1 0.096 12.0 4.1 1.6 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 EKX44265.1 - 0.047 13.9 12.6 0.12 12.6 7.9 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DUF4820 PF16091.5 EKX44265.1 - 5.2 6.4 11.1 1 8.7 7.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Myc_N PF01056.18 EKX44265.1 - 6.7 6.5 23.1 1 9.2 18.3 1.9 1 1 1 2 2 2 0 Myc amino-terminal region Thioredoxin_6 PF13848.6 EKX44266.1 - 0.12 12.3 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain GBP PF02263.19 EKX44267.1 - 4.2e-20 72.1 0.0 1.1e-19 70.7 0.0 1.6 1 1 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 EKX44267.1 - 0.0036 17.4 0.0 0.0057 16.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EKX44267.1 - 0.013 15.6 0.1 0.021 14.9 0.1 1.4 1 1 0 1 1 1 0 Dynamin family AIG1 PF04548.16 EKX44267.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 AIG1 family RVT_N PF13655.6 EKX44268.1 - 0.023 14.9 0.1 6.4 7.1 0.1 2.7 2 0 0 2 2 2 0 N-terminal domain of reverse transcriptase DREV PF05219.12 EKX44269.1 - 1.1e-19 70.6 0.0 2.5e-13 49.7 0.0 3.0 1 1 1 2 2 2 2 DREV methyltransferase Methyltransf_25 PF13649.6 EKX44269.1 - 0.00033 21.3 0.1 0.0013 19.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 EKX44269.1 - 0.00045 19.9 0.0 0.00088 18.9 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_23 PF13489.6 EKX44269.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 EKX44269.1 - 0.023 13.7 0.0 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_11 PF08241.12 EKX44269.1 - 0.03 15.0 0.0 0.083 13.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.17 EKX44269.1 - 0.066 12.7 0.0 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_12 PF08242.12 EKX44269.1 - 0.076 13.8 0.0 0.15 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CPT PF07931.12 EKX44269.1 - 0.17 11.7 0.0 0.5 10.2 0.0 1.8 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Ank_4 PF13637.6 EKX44270.1 - 3e-47 158.4 0.7 3.7e-09 36.9 0.0 5.9 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX44270.1 - 8.7e-37 121.0 0.4 0.0026 18.1 0.0 7.1 7 0 0 7 7 7 7 Ankyrin repeat Ank_2 PF12796.7 EKX44270.1 - 4.9e-30 104.0 1.7 8.9e-08 32.6 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) DUF1843 PF08898.10 EKX44270.1 - 1.2e-13 51.3 2.0 7.7 7.1 0.0 7.1 7 0 0 7 7 7 4 Domain of unknown function (DUF1843) Ank PF00023.30 EKX44270.1 - 1.2e-11 44.5 7.2 1.5 9.4 0.0 6.9 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EKX44270.1 - 2.3e-10 40.5 3.7 2.4 8.6 0.0 6.7 1 1 6 7 7 7 3 Ankyrin repeats (many copies) Phage_T7_Capsid PF05396.11 EKX44270.1 - 9.2e-08 32.5 0.0 10 6.5 0.0 6.3 1 1 6 7 7 7 1 Phage T7 capsid assembly protein Toprim_4 PF13662.6 EKX44270.1 - 3.5e-06 27.4 7.4 65 4.1 0.0 7.0 4 2 1 7 7 7 0 Toprim domain DUF3655 PF12379.8 EKX44270.1 - 4e-05 23.8 18.7 21 5.5 0.2 6.9 1 1 6 7 7 7 0 Protein of unknown function (DUF3655) DUF4723 PF15851.5 EKX44270.1 - 0.0026 17.8 10.6 47 4.2 0.0 5.9 1 1 4 6 6 6 0 Domain of unknown function (DUF4723) S10_plectin PF03501.15 EKX44270.1 - 0.084 13.0 0.0 1.6e+02 2.4 0.0 3.9 1 1 3 5 5 5 0 Plectin/S10 domain DUF1685 PF07939.11 EKX44270.1 - 0.3 10.9 28.6 29 4.5 0.2 7.0 7 0 0 7 7 7 0 Protein of unknown function (DUF1685) zf-RING-like PF08746.11 EKX44270.1 - 0.48 10.8 29.8 15 6.0 0.2 6.7 7 0 0 7 7 7 0 RING-like domain ADPrib_exo_Tox PF03496.14 EKX44271.1 - 0.0011 18.4 0.0 0.0013 18.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosyltransferase exoenzyme ART PF01129.18 EKX44271.1 - 0.0013 18.1 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase Pkinase PF00069.25 EKX44272.1 - 2.6e-31 108.9 0.0 2.9e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX44272.1 - 1.3e-27 96.8 0.0 1.4e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX44272.1 - 0.0017 17.8 0.0 0.0021 17.5 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EKX44272.1 - 0.0094 14.8 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX44272.1 - 0.043 13.7 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pyridox_oxase_2 PF12766.7 EKX44273.1 - 1.9e-18 66.9 0.0 3.6e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 EKX44273.1 - 0.026 14.7 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase EF-hand_7 PF13499.6 EKX44274.1 - 2.8e-17 62.9 0.4 1.7e-11 44.4 0.2 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX44274.1 - 5.8e-14 50.5 5.3 7.7e-05 22.0 0.1 4.3 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 EKX44274.1 - 1.4e-13 49.6 1.6 2.5e-05 23.8 0.0 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_9 PF14658.6 EKX44274.1 - 2.4e-10 40.6 0.0 0.00031 21.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EKX44274.1 - 5.1e-06 26.2 1.5 0.034 14.0 0.0 3.3 2 1 1 3 3 3 3 EF-hand domain pair Ribosomal_L11 PF00298.19 EKX44274.1 - 0.0051 17.3 0.0 3.4 8.2 0.0 2.6 1 1 0 2 2 2 2 Ribosomal protein L11, RNA binding domain DUF1456 PF07308.13 EKX44274.1 - 0.017 15.4 1.7 7.5 7.0 0.0 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF1456) EF-hand_14 PF17959.1 EKX44274.1 - 0.021 15.2 0.0 1.6 9.1 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain GPHH PF16905.5 EKX44274.1 - 0.19 11.5 0.0 12 5.8 0.0 3.1 1 1 2 3 3 3 0 Voltage-dependent L-type calcium channel, IQ-associated zf-CCCH PF00642.24 EKX44275.1 - 2.4e-14 52.8 28.3 0.0002 21.2 1.5 4.1 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EKX44275.1 - 5.9e-11 42.0 29.7 0.00023 21.1 3.1 5.1 4 1 0 4 4 4 4 Zinc finger domain Torus PF16131.5 EKX44275.1 - 1.2e-08 35.7 20.3 0.0048 17.6 0.4 3.8 1 1 3 4 4 4 3 Torus domain zf-CCCH_3 PF15663.5 EKX44275.1 - 7.4e-07 29.4 12.4 2.2e-06 27.9 12.0 1.8 1 1 0 1 1 1 1 Zinc-finger containing family zf-CCCH_4 PF18044.1 EKX44275.1 - 4.4e-06 26.4 25.0 0.00056 19.7 0.5 4.7 5 0 0 5 5 5 3 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EKX44275.1 - 0.00019 21.8 21.6 0.06 13.8 2.2 3.9 5 0 0 5 5 5 3 RNA-binding, Nab2-type zinc finger zf-C3H1 PF10650.9 EKX44275.1 - 0.021 14.5 5.2 0.021 14.5 5.2 3.6 4 1 0 4 4 4 0 Putative zinc-finger domain Anillin_N PF16018.5 EKX44277.1 - 0.046 14.3 4.5 0.18 12.4 0.3 3.1 2 0 0 2 2 2 0 Anillin N-terminus Ribosomal_L1 PF00687.21 EKX44278.1 - 5.7e-49 166.6 1.5 5.7e-49 166.6 1.5 2.0 2 1 0 2 2 2 1 Ribosomal protein L1p/L10e family EMC3_TMCO1 PF01956.16 EKX44278.1 - 0.21 11.3 3.0 0.21 11.3 0.6 2.2 2 1 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Mitofilin PF09731.9 EKX44278.1 - 0.29 9.9 20.0 0.42 9.4 20.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein VGLL4 PF15245.6 EKX44278.1 - 1.2 9.2 9.5 2 8.4 9.5 1.4 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 Presenilin PF01080.17 EKX44278.1 - 2.5 6.8 8.7 3.6 6.2 8.7 1.1 1 0 0 1 1 1 0 Presenilin UCH PF00443.29 EKX44279.1 - 1.1e-44 152.9 0.0 1.6e-44 152.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 EKX44279.1 - 5.4e-22 77.3 0.0 5.1e-21 74.2 0.0 2.3 2 0 0 2 2 2 1 Variant UBP zinc finger UBA PF00627.31 EKX44279.1 - 5.6e-22 77.3 0.1 3.9e-10 39.4 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 EKX44279.1 - 4.1e-14 52.9 0.0 1.4e-10 41.3 0.0 2.4 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EKX44279.1 - 2.1e-09 37.5 0.0 1.8e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UBA_3 PF09288.10 EKX44279.1 - 0.02 14.7 0.0 2.9 7.8 0.0 2.8 3 0 0 3 3 3 0 Fungal ubiquitin-associated domain Arf PF00025.21 EKX44280.1 - 2.3e-70 235.6 0.9 2.6e-70 235.4 0.9 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EKX44280.1 - 6.3e-13 49.0 0.1 9e-13 48.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EKX44280.1 - 1.5e-12 47.3 0.0 2e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EKX44280.1 - 6.1e-12 45.4 0.7 2.7e-06 26.8 0.1 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EKX44280.1 - 2.9e-11 43.2 0.0 3.4e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EKX44280.1 - 1.4e-09 37.6 0.0 1.7e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EKX44280.1 - 4.1e-07 30.1 0.0 8.2e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EKX44280.1 - 1.7e-05 24.4 0.0 8.9e-05 22.1 0.0 1.8 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 EKX44280.1 - 0.0017 17.8 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein MeaB PF03308.16 EKX44280.1 - 0.0029 16.6 0.2 0.089 11.8 0.1 2.4 2 1 1 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 EKX44280.1 - 0.032 13.8 0.2 0.06 12.9 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B 6PF2K PF01591.18 EKX44280.1 - 0.092 12.0 0.0 0.12 11.7 0.0 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase PduV-EutP PF10662.9 EKX44280.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Tom37 PF10568.9 EKX44281.1 - 1.8e-23 83.2 0.1 4.3e-23 82.0 0.1 1.6 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 EKX44281.1 - 2.4e-23 81.7 0.1 5.2e-23 80.6 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EKX44281.1 - 5.6e-19 68.7 0.0 1.2e-18 67.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 EKX44281.1 - 2.4e-06 27.5 0.0 7.2e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EKX44281.1 - 0.014 15.6 0.1 0.059 13.6 0.0 1.9 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Na_H_antiporter PF03553.14 EKX44283.1 - 6e-40 137.4 23.1 6.5e-39 134.0 11.9 2.6 1 1 2 3 3 3 2 Na+/H+ antiporter family E1_DerP2_DerF2 PF02221.15 EKX44284.1 - 1.3e-11 45.1 0.1 1.7e-11 44.7 0.1 1.2 1 0 0 1 1 1 1 ML domain EF-hand_7 PF13499.6 EKX44285.1 - 0.00088 19.7 0.1 0.48 10.9 0.0 3.7 3 0 0 3 3 3 1 EF-hand domain pair VWA PF00092.28 EKX44285.1 - 0.013 15.7 0.0 4.6 7.5 0.0 2.7 2 0 0 2 2 2 0 von Willebrand factor type A domain HTH_44 PF14641.6 EKX44285.1 - 0.015 15.7 1.2 0.045 14.2 1.2 1.8 1 0 0 1 1 1 0 Helix-turn-helix DNA-binding domain of SPT6 SIR2_2 PF13289.6 EKX44285.1 - 0.055 13.6 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 SIR2-like domain PTS_2-RNA PF01885.16 EKX44285.1 - 0.083 12.9 1.5 0.28 11.2 1.5 1.9 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF4061 PF13270.6 EKX44285.1 - 5.1 7.5 6.4 6.2 7.2 3.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) BTB_2 PF02214.22 EKX44286.1 - 4.1e-17 62.3 0.0 6.9e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EKX44286.1 - 0.037 14.3 0.0 0.077 13.2 0.0 1.5 2 0 0 2 2 2 0 BTB/POZ domain Ank_4 PF13637.6 EKX44287.1 - 0.062 13.9 0.0 3.1 8.5 0.0 2.4 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX44287.1 - 0.09 13.4 0.0 0.17 12.5 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) YabA PF06156.13 EKX44288.1 - 0.42 11.3 4.3 1.1 10.0 4.3 1.7 1 0 0 1 1 1 0 Initiation control protein YabA Ank_2 PF12796.7 EKX44289.1 - 7.2e-41 138.7 1.2 1.9e-10 41.2 0.0 5.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX44289.1 - 3.4e-35 120.0 0.2 2.3e-09 37.6 0.0 6.2 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX44289.1 - 6.2e-23 80.6 3.4 0.0031 17.8 0.0 7.3 2 1 5 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX44289.1 - 4.2e-18 63.6 0.1 0.21 12.2 0.0 8.2 9 0 0 9 9 9 3 Ankyrin repeat Ank PF00023.30 EKX44289.1 - 1.7e-14 53.5 0.1 1.1 9.9 0.0 7.7 9 0 0 9 9 9 4 Ankyrin repeat Ins_beta PF03488.14 EKX44289.1 - 0.00099 19.1 9.7 7.2 6.7 0.0 6.3 7 0 0 7 7 7 1 Nematode insulin-related peptide beta type BDHCT PF08072.11 EKX44289.1 - 0.022 14.8 14.7 14 5.9 0.1 6.2 6 0 0 6 6 6 0 BDHCT (NUC031) domain DUF5642 PF18702.1 EKX44289.1 - 0.03 14.1 2.6 1.8 8.3 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF5642) Mo-nitro_C PF06967.11 EKX44289.1 - 0.28 11.2 0.8 57 3.8 0.0 4.2 6 0 0 6 6 6 0 Mo-dependent nitrogenase C-terminus ShK PF01549.24 EKX44289.1 - 1.2 9.7 7.7 47 4.6 0.1 5.2 5 0 0 5 5 5 0 ShK domain-like PARP PF00644.20 EKX44290.1 - 7.1e-26 91.0 0.0 8.3e-25 87.5 0.0 2.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain DUF4536 PF15055.6 EKX44290.1 - 0.12 12.6 0.0 0.32 11.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) Pkinase PF00069.25 EKX44291.1 - 5.8e-42 143.9 0.0 2e-40 138.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX44291.1 - 9.1e-25 87.4 0.0 1.1e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX44291.1 - 3.6e-08 32.6 0.0 9.9e-07 27.9 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EKX44291.1 - 3.9e-05 23.1 0.1 5.4e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX44291.1 - 0.0069 16.3 0.3 0.13 12.2 0.0 2.3 1 1 2 3 3 3 1 Phosphotransferase enzyme family TTL PF03133.15 EKX44293.1 - 6e-70 235.7 0.0 7.5e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EKX44293.1 - 8e-07 28.6 0.0 1.8e-05 24.1 0.0 2.5 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EKX44293.1 - 3.2e-05 23.3 0.0 0.0016 17.8 0.0 2.2 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EKX44293.1 - 6.2e-05 23.1 0.0 0.022 14.8 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EKX44293.1 - 0.0064 16.0 0.0 0.016 14.7 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.11 EKX44293.1 - 0.025 14.2 0.0 4.7 6.8 0.0 2.5 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Tankyrase_bdg_C PF15327.6 EKX44293.1 - 0.031 14.7 0.1 0.11 12.9 0.0 1.8 2 0 0 2 2 2 0 Tankyrase binding protein C terminal domain Methyltransf_33 PF10017.9 EKX44293.1 - 0.048 12.8 0.3 0.15 11.2 0.1 1.8 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent Pkinase PF00069.25 EKX44294.1 - 4.4e-40 137.7 0.0 5.4e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX44294.1 - 6e-39 133.9 0.0 6.9e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX44294.1 - 0.0091 15.9 0.0 0.32 10.9 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EKX44294.1 - 0.01 14.8 0.0 0.018 14.0 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain Laminin_B PF00052.18 EKX44298.1 - 2.9e-06 27.2 0.0 8.8e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 Laminin B (Domain IV) DUF2749 PF10907.8 EKX44298.1 - 0.041 14.0 0.4 13 6.1 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2749) Ephrin_rec_like PF07699.13 EKX44299.1 - 6.3e-26 89.9 47.0 3.1e-07 30.1 4.6 4.9 4 0 0 4 4 4 4 Putative ephrin-receptor like EGF_CA PF07645.15 EKX44299.1 - 1.7e-19 69.7 35.9 3e-09 36.9 4.6 9.7 7 3 1 9 9 9 3 Calcium-binding EGF domain hEGF PF12661.7 EKX44299.1 - 1.3e-06 28.8 62.2 6.7e-05 23.4 4.9 9.9 10 0 0 10 10 10 2 Human growth factor-like EGF cEGF PF12662.7 EKX44299.1 - 2.3e-06 27.4 13.4 0.00012 21.9 0.3 10.0 10 1 1 11 11 11 4 Complement Clr-like EGF-like EGF_3 PF12947.7 EKX44299.1 - 2.7e-06 27.4 67.6 1.7e-05 24.9 4.2 8.7 9 0 0 9 9 9 3 EGF domain EGF_MSP1_1 PF12946.7 EKX44299.1 - 0.00074 19.5 55.1 0.064 13.3 3.8 8.1 8 0 0 8 8 8 5 MSP1 EGF domain 1 EGF PF00008.27 EKX44299.1 - 0.0019 18.5 6.5 0.0019 18.5 6.5 9.8 9 2 0 9 9 9 2 EGF-like domain Ig_Tie2_1 PF10430.9 EKX44299.1 - 9.3 6.7 8.8 15 6.1 0.2 2.9 3 0 0 3 3 3 0 Tie-2 Ig-like domain 1 APOBEC1 PF18769.1 EKX44300.1 - 0.11 12.8 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 APOBEC1 Exonuc_VII_L PF02601.15 EKX44301.1 - 0.017 14.7 3.1 0.022 14.3 3.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DLP_helical PF18709.1 EKX44301.1 - 0.29 10.3 5.0 0.37 10.0 5.0 1.1 1 0 0 1 1 1 0 Dynamin-like helical domain DBINO PF13892.6 EKX44301.1 - 0.31 11.4 12.0 4.1 7.8 0.1 2.3 1 1 1 2 2 2 0 DNA-binding domain DDE_Tnp_IS66 PF03050.14 EKX44301.1 - 0.42 10.0 6.7 0.92 8.9 6.1 1.7 1 1 1 2 2 2 0 Transposase IS66 family RGS_DHEX PF18148.1 EKX44301.1 - 0.72 10.0 3.7 1.5 9.0 3.7 1.4 1 0 0 1 1 1 0 Regulator of G-protein signalling DHEX domain Glyco_transf_41 PF13844.6 EKX44302.1 - 4.8e-113 378.1 0.4 3.3e-62 210.5 0.0 2.0 1 1 1 2 2 2 2 Glycosyl transferase family 41 Arm PF00514.23 EKX44303.1 - 1.5e-05 24.9 10.0 0.4 10.8 0.1 5.2 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EKX44303.1 - 0.00064 20.2 0.8 0.074 13.6 0.1 3.3 3 0 0 3 3 3 1 HEAT-like repeat RICTOR_V PF14668.6 EKX44303.1 - 0.046 14.0 0.1 2.3 8.5 0.1 3.3 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 Lambda_tail_I PF06805.12 EKX44303.1 - 0.18 12.2 0.0 4.9 7.6 0.0 2.7 2 0 0 2 2 2 0 Bacteriophage lambda tail assembly protein I Methyltransf_16 PF10294.9 EKX44304.1 - 2.8e-28 98.8 0.4 4e-28 98.3 0.4 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 EKX44304.1 - 1.7e-06 27.7 0.1 2.6e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EKX44304.1 - 2.9e-06 26.9 0.1 4.6e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 EKX44304.1 - 0.0024 17.5 0.0 0.0037 16.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 TRM PF02005.16 EKX44304.1 - 0.0069 15.6 0.0 0.015 14.5 0.0 1.4 2 0 0 2 2 2 1 N2,N2-dimethylguanosine tRNA methyltransferase Malic_M PF03949.15 EKX44304.1 - 0.0091 15.3 0.0 0.71 9.1 0.0 2.1 2 0 0 2 2 2 2 Malic enzyme, NAD binding domain MethyltransfD12 PF02086.15 EKX44304.1 - 0.038 13.7 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_31 PF13847.6 EKX44304.1 - 0.074 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF4686 PF15742.5 EKX44305.1 - 0.005 16.0 5.7 0.005 16.0 5.7 3.0 1 1 0 2 2 2 1 Domain of unknown function (DUF4686) PG_binding_4 PF12229.8 EKX44305.1 - 0.075 13.3 2.5 0.08 13.2 0.7 2.0 2 0 0 2 2 2 0 Putative peptidoglycan binding domain DUF4407 PF14362.6 EKX44305.1 - 0.28 10.5 14.6 0.69 9.2 9.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 EKX44305.1 - 1.8 8.6 12.3 1 9.4 0.2 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Shugoshin_N PF07558.11 EKX44305.1 - 3.5 7.6 18.6 0.2 11.5 1.0 5.0 4 1 1 5 5 5 0 Shugoshin N-terminal coiled-coil region Spc7 PF08317.11 EKX44305.1 - 3.6 6.4 27.9 5.2 5.9 17.3 2.6 2 0 0 2 2 2 0 Spc7 kinetochore protein Taxilin PF09728.9 EKX44305.1 - 5.9 6.0 40.1 0.4 9.8 2.5 2.9 3 0 0 3 3 3 0 Myosin-like coiled-coil protein GrpE PF01025.19 EKX44305.1 - 7.3 6.2 24.0 1.5 8.4 4.8 3.4 2 1 1 3 3 3 0 GrpE LMBR1 PF04791.16 EKX44305.1 - 7.9 5.3 13.1 40 2.9 10.8 2.3 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF1492 PF07374.11 EKX44305.1 - 9.1 6.5 10.1 3.6 7.8 0.8 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1492) Myosin_head PF00063.21 EKX44306.1 - 2.2e-176 588.0 0.0 4.9e-176 586.9 0.0 1.5 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 EKX44306.1 - 0.0015 18.3 0.4 0.0027 17.5 0.4 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 EKX44306.1 - 0.019 15.4 0.0 0.069 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EKX44306.1 - 0.045 14.0 0.0 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF4266 PF14086.6 EKX44306.1 - 0.81 10.7 3.2 1.3 10.0 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4266) Malic_M PF03949.15 EKX44307.1 - 7.5e-89 297.4 0.0 9.3e-89 297.1 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EKX44307.1 - 2.7e-68 229.3 0.0 4.3e-68 228.7 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain XPG_I PF00867.18 EKX44308.1 - 0.00044 20.5 0.1 0.001 19.4 0.1 1.7 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 EKX44308.1 - 0.0022 17.5 0.2 0.0059 16.1 0.0 1.8 2 0 0 2 2 2 1 XPG domain containing XPG_N PF00752.17 EKX44308.1 - 0.018 15.5 0.0 0.056 13.9 0.0 1.9 2 0 0 2 2 2 0 XPG N-terminal domain FmrO PF07091.11 EKX44308.1 - 0.035 13.7 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) ERM PF00769.19 EKX44310.1 - 0.079 12.8 12.7 0.15 11.9 12.7 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family SAS-6_N PF16531.5 EKX44310.1 - 0.18 12.4 1.4 0.43 11.2 0.9 1.8 1 1 1 2 2 2 0 Centriolar protein SAS N-terminal DUF3450 PF11932.8 EKX44310.1 - 0.25 10.6 9.5 0.4 9.9 9.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Focal_AT PF03623.13 EKX44310.1 - 0.25 11.3 4.2 2.1 8.4 0.1 2.4 2 1 0 2 2 2 0 Focal adhesion targeting region OmpH PF03938.14 EKX44310.1 - 0.29 11.5 9.1 0.37 11.1 7.8 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF5595 PF18077.1 EKX44310.1 - 0.38 10.9 10.6 0.48 10.5 0.3 3.4 2 1 2 4 4 4 0 Domain of unknown function (DUF5595) Jnk-SapK_ap_N PF09744.9 EKX44310.1 - 1.1 9.5 18.5 0.89 9.8 8.9 2.6 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 DUF4200 PF13863.6 EKX44310.1 - 1.8 9.0 17.3 1.1 9.6 14.2 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) FUSC PF04632.12 EKX44311.1 - 3 6.3 10.7 3.2 6.2 10.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4337 PF14235.6 EKX44311.1 - 8 6.5 12.0 1.5 8.9 5.0 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4337) THOC7 PF05615.13 EKX44311.1 - 9 6.6 22.5 0.34 11.2 6.1 2.5 1 1 1 2 2 2 0 Tho complex subunit 7 SANT_DAMP1_like PF16282.5 EKX44313.1 - 1.2e-21 76.7 2.6 1.2e-21 76.7 2.6 1.8 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 DUF5401 PF17380.2 EKX44313.1 - 2.2 6.2 10.2 2.9 5.9 10.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) zf-RING_UBOX PF13445.6 EKX44314.1 - 6.8e-06 26.0 4.5 1.1e-05 25.3 4.5 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EKX44314.1 - 8.5e-05 22.3 3.5 0.00013 21.7 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX44314.1 - 8.6e-05 22.8 4.0 0.00013 22.2 4.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EKX44314.1 - 0.00018 21.3 3.7 0.00025 20.8 3.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX44314.1 - 0.00025 20.9 3.4 0.00042 20.2 3.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EKX44314.1 - 0.00033 20.5 6.6 0.001 18.9 6.7 1.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EKX44314.1 - 0.0019 18.0 4.2 0.0029 17.4 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EKX44314.1 - 0.032 14.4 5.6 0.064 13.4 5.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Methyltransf_PK PF05891.12 EKX44315.1 - 0.054 13.0 0.2 0.095 12.2 0.2 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Antigen_Bd37 PF11641.8 EKX44315.1 - 0.061 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein Ephrin_rec_like PF07699.13 EKX44316.1 - 4.4e-18 64.8 154.5 0.00049 19.8 11.6 13.6 7 4 5 13 13 13 12 Putative ephrin-receptor like NCD3G PF07562.14 EKX44316.1 - 2.3e-10 40.3 107.1 0.0067 16.4 5.5 12.7 8 2 3 13 13 13 10 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX44316.1 - 2.9e-07 30.8 132.9 0.046 14.1 0.1 16.6 9 6 6 15 15 15 12 TNFR/NGFR cysteine-rich region Ephrin_rec_like PF07699.13 EKX44317.1 - 9.6e-09 34.9 72.9 0.00029 20.5 9.6 8.7 1 1 9 10 10 10 7 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX44317.1 - 3.2e-05 24.2 60.9 0.0024 18.2 1.6 8.3 7 1 1 8 8 8 5 TNFR/NGFR cysteine-rich region Lustrin_cystein PF14625.6 EKX44317.1 - 0.72 10.3 87.7 0.16 12.4 6.3 9.5 4 2 4 8 8 8 0 Lustrin, cysteine-rich repeated domain Ephrin_rec_like PF07699.13 EKX44318.1 - 0.0001 22.0 51.0 0.0024 17.6 3.3 6.2 4 2 2 7 7 7 3 Putative ephrin-receptor like FluMu_N PF17891.1 EKX44318.1 - 0.099 12.4 0.0 0.24 11.2 0.0 1.6 2 0 0 2 2 2 0 Mu-like prophage FluMu N-terminal domain Ephrin_rec_like PF07699.13 EKX44319.1 - 2.6e-18 65.5 831.8 0.0021 17.8 6.4 71.4 59 13 14 74 74 74 46 Putative ephrin-receptor like SBBP PF06739.11 EKX44319.1 - 1.6e-05 24.8 9.5 10 6.2 0.1 7.2 6 0 0 6 6 6 3 Beta-propeller repeat C2 PF00168.30 EKX44321.1 - 9.2e-43 144.7 0.8 4.4e-21 75.1 0.1 2.9 3 0 0 3 3 3 2 C2 domain PTEN_C2 PF10409.9 EKX44321.1 - 0.00015 21.5 1.6 0.017 14.9 1.4 2.9 2 1 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein WSD PF15613.6 EKX44321.1 - 0.00062 20.2 3.7 0.0028 18.1 3.7 2.2 1 0 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Cas_Cas5d PF09704.10 EKX44321.1 - 0.0059 16.5 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Cas5) RRM_1 PF00076.22 EKX44321.1 - 0.024 14.4 1.2 0.065 13.1 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VEG PF06257.11 EKX44321.1 - 0.056 13.5 0.0 0.25 11.4 0.0 2.1 1 0 0 1 1 1 0 Biofilm formation stimulator VEG AIF_C PF14721.6 EKX44321.1 - 5.7 7.3 8.0 22 5.4 0.0 3.1 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Scm3 PF10384.9 EKX44322.1 - 0.00068 19.3 0.5 0.0018 17.9 0.0 1.9 2 0 0 2 2 2 1 Centromere protein Scm3 MPS2 PF17060.5 EKX44323.1 - 0.051 12.8 0.9 0.072 12.3 0.9 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 BLOC1_2 PF10046.9 EKX44323.1 - 0.095 13.0 0.5 0.16 12.2 0.5 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 EKX44323.1 - 1.2 9.8 4.8 0.89 10.2 2.8 1.8 1 1 1 2 2 2 0 SlyX DivIC PF04977.15 EKX44323.1 - 1.3 8.8 3.9 0.86 9.4 1.0 2.0 1 1 0 1 1 1 0 Septum formation initiator GILT PF03227.16 EKX44324.1 - 9.2e-15 54.8 0.0 3.2e-14 53.1 0.0 1.9 1 1 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) PSII_BNR PF14870.6 EKX44325.1 - 3.2e-12 46.3 2.1 9.2e-08 31.7 0.1 2.3 1 1 1 2 2 2 2 Photosynthesis system II assembly factor YCF48 Sortilin-Vps10 PF15902.5 EKX44325.1 - 5.6e-07 28.7 0.6 0.0019 17.1 0.1 2.0 1 1 1 2 2 2 2 Sortilin, neurotensin receptor 3, BNR PF02012.20 EKX44325.1 - 0.0043 16.8 15.2 0.4 10.9 0.5 4.3 4 0 0 4 4 4 2 BNR/Asp-box repeat CHB_HEX_C PF03174.13 EKX44325.1 - 0.03 14.3 0.1 3.6 7.6 0.0 2.7 3 0 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain Peptidase_C2 PF00648.21 EKX44326.1 - 6.7e-149 494.8 0.0 2e-80 270.0 0.0 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease Calpain_III PF01067.22 EKX44326.1 - 1.1e-23 84.0 0.0 2.1e-10 41.0 0.0 3.1 3 0 0 3 3 3 2 Calpain large subunit, domain III PepSY_like PF11396.8 EKX44326.1 - 0.18 12.4 0.1 23 5.6 0.0 2.9 3 0 0 3 3 3 0 Putative beta-lactamase-inhibitor-like, PepSY-like MBOAT PF03062.19 EKX44327.1 - 1.2e-21 77.5 7.1 1.9e-14 53.8 0.4 2.6 2 2 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family DUF4738 PF15889.5 EKX44328.1 - 9.1e-09 35.3 1.2 1.3 8.8 0.0 5.8 1 1 6 7 7 7 6 Domain of unknown function (DUF4738) Cpn10 PF00166.21 EKX44328.1 - 0.0012 18.8 6.2 35 4.6 0.2 5.3 1 1 5 6 6 6 2 Chaperonin 10 Kd subunit AMP-binding_C PF13193.6 EKX44328.1 - 0.17 12.9 15.7 11 7.1 1.0 4.7 1 1 4 5 5 5 0 AMP-binding enzyme C-terminal domain WD40 PF00400.32 EKX44329.1 - 1e-22 79.9 8.3 4.2e-06 27.4 0.1 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX44329.1 - 9.9e-05 22.6 0.1 0.057 13.7 0.0 4.2 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 EKX44329.1 - 0.059 13.1 1.7 4.6 6.9 0.0 3.1 3 1 1 4 4 4 0 TUP1-like enhancer of split AAA_2 PF07724.14 EKX44330.1 - 8.3e-43 146.4 0.1 2e-34 119.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 EKX44330.1 - 1.3e-13 51.5 0.7 1.6e-05 25.3 0.0 3.2 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EKX44330.1 - 1.1e-06 28.7 0.8 7.9e-05 22.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) MCM PF00493.23 EKX44330.1 - 3.7e-06 26.2 0.3 0.00047 19.3 0.0 2.5 2 0 0 2 2 2 1 MCM P-loop domain RuvB_N PF05496.12 EKX44330.1 - 4.4e-05 23.3 0.6 0.0022 17.7 0.2 2.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EKX44330.1 - 6.7e-05 23.2 0.6 0.00089 19.5 0.0 2.7 1 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.21 EKX44330.1 - 0.0001 21.8 0.2 0.0078 15.6 0.0 3.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ClpB_D2-small PF10431.9 EKX44330.1 - 0.00013 21.9 3.1 0.00061 19.8 0.1 2.6 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.6 EKX44330.1 - 0.00044 20.7 0.0 0.0011 19.4 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EKX44330.1 - 0.00067 20.2 1.3 0.0042 17.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 EKX44330.1 - 0.005 17.0 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EKX44330.1 - 0.005 16.5 0.3 0.062 13.0 0.0 2.5 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_28 PF13521.6 EKX44330.1 - 0.01 16.1 0.0 0.047 13.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EKX44330.1 - 0.022 14.5 0.1 0.08 12.7 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein IPT PF01745.16 EKX44330.1 - 0.024 14.0 0.0 0.051 13.0 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase TsaE PF02367.17 EKX44330.1 - 0.035 14.1 0.1 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 EKX44330.1 - 0.044 13.8 0.4 0.2 11.6 0.4 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit TniB PF05621.11 EKX44330.1 - 0.065 12.6 0.5 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein DEAD PF00270.29 EKX44330.1 - 0.14 11.9 1.2 1.8 8.3 0.0 3.0 3 1 0 3 3 2 0 DEAD/DEAH box helicase AAA_24 PF13479.6 EKX44330.1 - 0.62 9.7 5.4 0.14 11.8 0.2 2.4 3 1 0 3 3 3 0 AAA domain SAP PF02037.27 EKX44331.1 - 0.0024 17.6 1.5 0.0044 16.7 1.5 1.5 1 0 0 1 1 1 1 SAP domain PRK PF00485.18 EKX44332.1 - 3.4e-12 46.5 0.0 4e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EKX44332.1 - 1.3e-07 32.2 0.0 4.8e-07 30.4 0.0 2.0 1 1 1 2 2 2 1 AAA domain MeaB PF03308.16 EKX44332.1 - 5.8e-06 25.5 0.0 9e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 EKX44332.1 - 4.3e-05 23.7 0.2 0.0016 18.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EKX44332.1 - 0.00033 20.6 0.0 0.00056 19.9 0.0 1.3 1 0 0 1 1 1 1 NTPase NB-ARC PF00931.22 EKX44332.1 - 0.00047 19.4 0.0 0.0011 18.2 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain AAA_25 PF13481.6 EKX44332.1 - 0.00063 19.4 0.0 0.00099 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EKX44332.1 - 0.00071 20.0 0.0 0.00099 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EKX44332.1 - 0.00092 18.5 0.1 0.0017 17.7 0.0 1.5 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.6 EKX44332.1 - 0.00094 19.6 1.8 0.0047 17.4 0.2 2.6 2 1 1 3 3 3 1 AAA domain ATP_bind_1 PF03029.17 EKX44332.1 - 0.0019 18.0 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MipZ PF09140.11 EKX44332.1 - 0.005 16.1 0.2 0.013 14.8 0.0 1.7 2 0 0 2 2 2 1 ATPase MipZ AAA_22 PF13401.6 EKX44332.1 - 0.0068 16.7 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 EKX44332.1 - 0.009 15.8 0.3 0.013 15.2 0.0 1.5 2 0 0 2 2 1 1 Cytidylate kinase AAA PF00004.29 EKX44332.1 - 0.012 16.0 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ADK PF00406.22 EKX44332.1 - 0.013 15.6 0.8 0.49 10.5 0.1 2.2 2 0 0 2 2 2 0 Adenylate kinase AAA_30 PF13604.6 EKX44332.1 - 0.014 15.1 0.0 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 EKX44332.1 - 0.015 14.8 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 APS_kinase PF01583.20 EKX44332.1 - 0.017 15.0 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase SRP54 PF00448.22 EKX44332.1 - 0.024 14.3 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 EKX44332.1 - 0.028 14.8 0.0 0.05 14.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase CoaE PF01121.20 EKX44332.1 - 0.037 13.7 1.0 2.1 8.0 0.1 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase ABC_tran PF00005.27 EKX44332.1 - 0.061 13.8 0.0 0.19 12.2 0.1 1.5 1 1 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.18 EKX44332.1 - 0.063 13.0 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 EKX44332.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EKX44332.1 - 0.066 12.9 0.3 0.2 11.4 0.0 1.9 2 1 1 3 3 2 0 AAA domain NACHT PF05729.12 EKX44332.1 - 0.082 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Ploopntkinase3 PF18751.1 EKX44332.1 - 0.084 12.8 1.3 0.5 10.3 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Thymidylate_kin PF02223.17 EKX44332.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase MMR_HSR1 PF01926.23 EKX44332.1 - 0.13 12.3 0.1 0.29 11.2 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase KAP_NTPase PF07693.14 EKX44332.1 - 0.14 11.3 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_28 PF13521.6 EKX44332.1 - 0.17 12.1 2.6 0.66 10.2 2.5 2.3 1 1 0 1 1 1 0 AAA domain WD40 PF00400.32 EKX44333.1 - 4.4e-23 81.1 8.8 7.5e-06 26.6 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 EKX44333.1 - 4.7e-18 65.2 0.1 1.7e-16 60.2 0.0 2.9 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 EKX44333.1 - 2.9e-06 27.5 2.9 0.0022 18.3 0.1 4.1 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EKX44333.1 - 0.0051 16.7 0.9 0.01 15.7 0.1 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cofac_haem_bdg PF04187.13 EKX44334.1 - 5.9e-40 137.5 0.9 8.8e-25 87.9 0.0 3.0 3 0 0 3 3 3 3 Haem-binding uptake, Tiki superfamily, ChaN CBFD_NFYB_HMF PF00808.23 EKX44337.1 - 0.0075 16.5 0.1 0.019 15.3 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Med3 PF11593.8 EKX44337.1 - 0.12 11.5 9.1 0.24 10.6 9.1 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal OB_RNB PF08206.11 EKX44337.1 - 0.14 11.8 1.3 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease B OB domain RskA PF10099.9 EKX44337.1 - 0.2 12.0 3.8 1.1 9.5 0.2 2.4 2 0 0 2 2 2 0 Anti-sigma-K factor rskA TFIIA PF03153.13 EKX44337.1 - 0.51 10.3 24.2 2 8.3 14.9 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Senescence_reg PF04520.13 EKX44337.1 - 1.6 9.5 9.1 3.6 8.4 0.3 3.0 3 0 0 3 3 3 0 Senescence regulator Coilin_N PF15862.5 EKX44337.1 - 5.5 6.8 19.0 17 5.2 0.2 3.4 3 0 0 3 3 3 0 Coilin N-terminus TFB6 PF17110.5 EKX44337.1 - 6.9 6.4 15.5 1.2 8.9 0.2 3.3 3 0 0 3 3 3 0 Subunit 11 of the general transcription factor TFIIH Presenilin PF01080.17 EKX44337.1 - 7.3 5.2 12.2 1.4 7.6 0.4 2.6 3 0 0 3 3 3 0 Presenilin RPN2_C PF18004.1 EKX44337.1 - 9.2 6.2 26.0 0.097 12.6 0.7 3.4 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN2 C-terminal domain Cyt-b5 PF00173.28 EKX44338.1 - 1.1e-20 73.5 0.1 1.2e-20 73.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HMGL-like PF00682.19 EKX44339.1 - 2e-13 50.5 0.0 2.4e-10 40.4 0.0 2.2 2 0 0 2 2 2 2 HMGL-like DnaJ PF00226.31 EKX44340.1 - 1.9e-25 88.8 3.3 2.1e-25 88.6 3.3 1.0 1 0 0 1 1 1 1 DnaJ domain EF-hand_6 PF13405.6 EKX44341.1 - 0.0036 17.1 0.1 0.0083 16.0 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 EKX44341.1 - 0.039 13.5 0.0 0.076 12.6 0.0 1.5 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 EKX44341.1 - 0.055 13.9 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair Peptidase_C48 PF02902.19 EKX44342.1 - 8.2e-16 58.5 0.0 1.1e-15 58.1 0.0 1.0 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Lys PF00062.20 EKX44344.1 - 0.024 14.9 0.0 0.034 14.4 0.0 1.2 1 0 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family DUF1281_C PF18406.1 EKX44345.1 - 0.086 12.5 0.7 0.22 11.2 0.7 1.9 1 1 0 1 1 1 0 Ferredoxin-like domain in Api92-like protein DUF1281_C PF18406.1 EKX44347.1 - 0.078 12.7 1.0 0.21 11.3 1.0 1.9 1 1 0 1 1 1 0 Ferredoxin-like domain in Api92-like protein Lys PF00062.20 EKX44348.1 - 0.044 14.0 0.0 0.064 13.5 0.0 1.2 1 0 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family PAP_assoc PF03828.19 EKX44349.1 - 6.8e-14 51.8 0.0 1.8e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase PAP_central PF04928.17 EKX44349.1 - 0.017 14.1 0.0 0.04 12.9 0.0 1.5 2 0 0 2 2 2 0 Poly(A) polymerase central domain DUF3641 PF12345.8 EKX44349.1 - 0.078 13.0 0.0 3.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3641) Ephrin_rec_like PF07699.13 EKX44350.1 - 1e-12 47.6 14.3 2e-10 40.3 4.0 2.5 2 0 0 2 2 2 2 Putative ephrin-receptor like DUF2417 PF10329.9 EKX44350.1 - 0.2 11.1 3.8 0.35 10.2 3.8 1.4 1 0 0 1 1 1 0 Region of unknown function (DUF2417) SoxY PF13501.6 EKX44351.1 - 0.016 15.4 0.0 13 6.0 0.0 2.8 1 1 2 3 3 3 0 Sulfur oxidation protein SoxY PTS_EIIB PF00367.20 EKX44351.1 - 7.7 6.1 8.8 1.1e+02 2.4 0.1 4.0 4 0 0 4 4 4 0 phosphotransferase system, EIIB DS PF01916.17 EKX44352.1 - 2.1e-123 411.2 0.0 2.4e-123 411.0 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Tropomyosin PF00261.20 EKX44353.1 - 0.038 13.3 1.8 0.055 12.8 1.8 1.2 1 0 0 1 1 1 0 Tropomyosin Pro_isomerase PF00160.21 EKX44354.1 - 4.2e-46 157.1 0.3 4.6e-46 157.0 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PglZ PF08665.12 EKX44355.1 - 0.041 14.0 1.1 1.3 9.1 0.1 2.5 2 1 1 3 3 3 0 PglZ domain Phosphodiest PF01663.22 EKX44356.1 - 7.8e-10 38.9 0.0 1.2e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1378 PF07125.11 EKX44356.1 - 0.31 11.2 1.1 0.72 10.1 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) Sporozoite_P67 PF05642.11 EKX44358.1 - 0.18 9.8 2.0 0.22 9.6 2.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Milton PF12448.8 EKX44359.1 - 0.041 14.0 0.4 0.19 11.9 0.4 1.8 1 1 0 1 1 1 0 Kinesin associated protein RRM_1 PF00076.22 EKX44360.1 - 1.7e-20 72.6 0.0 1.9e-20 72.5 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EKX44360.1 - 0.0027 17.5 0.0 0.0051 16.6 0.0 1.4 1 1 0 1 1 1 1 Occluded RNA-recognition motif RRM_7 PF16367.5 EKX44360.1 - 0.064 13.4 0.0 0.11 12.6 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif Nup35_RRM_2 PF14605.6 EKX44360.1 - 0.1 12.6 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif eIF-5_eIF-2B PF01873.17 EKX44362.1 - 3e-18 65.8 0.0 1.3e-17 63.8 0.0 2.0 1 1 0 1 1 1 1 Domain found in IF2B/IF5 Elf1 PF05129.13 EKX44362.1 - 0.0088 16.1 1.0 0.035 14.2 1.0 2.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like RXLR PF16810.5 EKX44362.1 - 4.1 7.8 8.4 1.6 9.1 4.4 2.2 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity DUF2058 PF09831.9 EKX44363.1 - 0.15 12.2 3.7 0.3 11.2 3.7 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF3915 PF13054.6 EKX44363.1 - 0.42 10.6 5.4 1.3 9.0 5.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3915) Serglycin PF04360.12 EKX44363.1 - 0.51 10.3 4.7 4.8 7.1 0.0 3.0 2 1 1 3 3 3 0 Serglycin Keratin_2_head PF16208.5 EKX44363.1 - 1 9.5 17.6 1.7 8.8 17.6 1.3 1 0 0 1 1 1 0 Keratin type II head LRR_8 PF13855.6 EKX44364.1 - 7.5e-13 48.0 7.8 2.6e-06 27.1 0.5 4.1 3 1 2 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 EKX44364.1 - 1.5e-11 44.4 7.5 0.00048 20.5 0.2 4.7 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EKX44364.1 - 1.6e-07 30.8 1.4 0.087 12.9 0.1 4.3 4 0 0 4 4 4 2 Leucine Rich repeat LRR_9 PF14580.6 EKX44364.1 - 7.9e-07 28.7 7.8 0.00011 21.8 0.4 3.4 1 1 1 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 EKX44364.1 - 0.001 19.3 3.0 1.3e+02 3.8 0.0 5.9 6 0 0 6 6 6 0 Leucine Rich Repeat RNase_H2_suC PF08615.11 EKX44366.1 - 5e-16 59.1 0.0 1.4e-13 51.2 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) EIAV_GP90 PF00971.18 EKX44366.1 - 0.23 10.1 0.0 0.28 9.8 0.0 1.1 1 0 0 1 1 1 0 EIAV coat protein, gp90 MyTH4 PF00784.17 EKX44368.1 - 0.033 14.7 0.0 0.059 13.9 0.0 1.4 1 0 0 1 1 1 0 MyTH4 domain FAM76 PF16046.5 EKX44368.1 - 0.078 12.3 12.1 0.12 11.7 12.1 1.3 1 0 0 1 1 1 0 FAM76 protein Spc7 PF08317.11 EKX44368.1 - 0.2 10.5 15.9 0.25 10.2 15.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 EKX44368.1 - 0.58 8.0 3.3 0.68 7.8 3.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM184 PF15665.5 EKX44368.1 - 1.3 8.8 17.5 21 4.8 17.3 2.2 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B Phlebovirus_NSM PF07246.11 EKX44368.1 - 1.8 7.9 13.2 3.1 7.1 13.2 1.4 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M ARD PF03079.14 EKX44368.1 - 2.2 8.4 8.3 0.22 11.7 1.0 2.0 1 1 1 2 2 2 0 ARD/ARD' family Atg14 PF10186.9 EKX44368.1 - 2.4 7.2 8.9 3.1 6.8 8.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YlqD PF11068.8 EKX44368.1 - 2.9 8.3 12.4 0.66 10.4 6.7 2.0 1 1 1 2 2 2 0 YlqD protein YabA PF06156.13 EKX44368.1 - 4.4 8.0 9.8 2.6 8.7 5.9 2.2 1 1 1 2 2 2 0 Initiation control protein YabA MSA-2c PF12238.8 EKX44368.1 - 6.8 6.6 7.0 8.1 6.4 5.3 1.8 1 1 1 2 2 2 0 Merozoite surface antigen 2c DUF883 PF05957.13 EKX44368.1 - 8.3 7.1 11.4 12 6.6 9.0 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Metallothi_Euk2 PF12809.7 EKX44369.1 - 0.013 15.7 16.7 0.16 12.3 3.1 2.8 1 1 1 2 2 2 0 Eukaryotic metallothionein DUF2188 PF09954.9 EKX44369.1 - 0.13 12.4 0.0 0.68 10.1 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) Alkyl_sulf_dimr PF14863.6 EKX44370.1 - 0.052 14.0 1.5 0.072 13.5 0.1 2.0 2 1 0 2 2 2 0 Alkyl sulfatase dimerisation Cyclase PF04199.13 EKX44370.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.8 1 1 0 1 1 1 0 Putative cyclase RabGAP-TBC PF00566.18 EKX44371.1 - 5.6e-26 91.5 0.3 1e-25 90.7 0.3 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain C2 PF00168.30 EKX44372.1 - 1.6e-32 111.8 0.1 7.1e-12 45.5 0.0 4.3 4 0 0 4 4 4 4 C2 domain CEP76-C2 PF15627.6 EKX44372.1 - 4.7e-05 23.0 0.3 0.2 11.2 0.0 3.3 3 0 0 3 3 3 3 CEP76 C2 domain AhpC-TSA PF00578.21 EKX44374.1 - 3.1e-35 120.8 0.0 4.3e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EKX44374.1 - 4.6e-22 78.3 0.0 6e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 EKX44374.1 - 0.0063 16.6 0.0 0.012 15.8 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.12 EKX44374.1 - 0.01 15.4 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) SCO1-SenC PF02630.14 EKX44374.1 - 0.02 14.8 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 SCO1/SenC Ank_4 PF13637.6 EKX44375.1 - 1.4e-30 105.3 0.8 3.1e-10 40.4 0.0 4.1 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX44375.1 - 9.2e-25 87.1 0.1 2e-11 44.3 0.0 2.5 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 EKX44375.1 - 1.6e-20 72.6 1.3 3e-06 27.4 0.2 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 EKX44375.1 - 1.3e-18 65.1 0.3 1.3e-05 25.2 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EKX44375.1 - 1.6e-18 66.5 0.9 5.2e-08 33.0 0.2 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) EccE PF11203.8 EKX44375.1 - 0.064 13.6 0.3 0.073 13.4 0.3 1.3 1 1 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE Ank_4 PF13637.6 EKX44376.1 - 5.1e-19 68.4 3.7 4.1e-06 27.2 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX44376.1 - 1.8e-16 60.5 0.1 2.4e-07 31.2 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX44376.1 - 9.3e-14 50.2 0.0 0.00013 22.2 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EKX44376.1 - 5.9e-12 45.6 1.1 5.4e-05 23.4 0.1 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX44376.1 - 5.2e-10 39.3 0.2 4.7e-05 23.7 0.1 4.0 4 0 0 4 4 4 1 Ankyrin repeat Pyridoxal_deC PF00282.19 EKX44376.1 - 0.046 12.4 0.1 0.052 12.3 0.1 1.0 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain VWA_3_C PF18571.1 EKX44376.1 - 0.12 12.3 0.1 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 von Willebrand factor type A C-terminal domain DUF234 PF03008.14 EKX44376.1 - 0.13 12.7 0.0 0.49 10.9 0.0 1.7 1 1 1 2 2 2 0 Archaea bacterial proteins of unknown function DnaJ PF00226.31 EKX44377.1 - 4.5e-16 58.7 0.0 7.4e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DUF4715 PF15835.5 EKX44379.1 - 0.00021 21.4 2.1 0.0014 18.7 0.9 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4715) DUF812 PF05667.11 EKX44379.1 - 0.0078 15.1 6.4 0.009 15.0 6.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) PhageMin_Tail PF10145.9 EKX44379.1 - 0.044 13.6 0.2 0.056 13.3 0.2 1.2 1 0 0 1 1 1 0 Phage-related minor tail protein DUF4407 PF14362.6 EKX44379.1 - 0.085 12.2 3.7 0.1 12.0 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM76 PF16046.5 EKX44379.1 - 1.4 8.2 5.1 1.6 8.0 5.1 1.1 1 0 0 1 1 1 0 FAM76 protein DnaJ_C PF01556.18 EKX44380.1 - 3.9e-28 98.4 0.0 8.5e-28 97.3 0.0 1.5 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 EKX44380.1 - 1.4e-11 44.6 13.2 2.2e-11 43.9 13.2 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EKX44380.1 - 2.2e-09 37.2 17.3 5.9e-05 22.9 4.9 2.3 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein DUF5351 PF17302.2 EKX44380.1 - 0.0044 17.2 16.1 3.7 7.8 0.3 4.3 4 0 0 4 4 4 2 Family of unknown function (DUF5351) HypA PF01155.19 EKX44380.1 - 0.045 13.8 9.8 0.3 11.1 2.3 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 EKX44380.1 - 0.071 13.5 13.1 8.9 6.8 6.7 3.3 1 1 1 2 2 2 0 Restriction alleviation protein Lar DnaJ PF00226.31 EKX44380.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 DnaJ domain DZR PF12773.7 EKX44380.1 - 2.1 8.4 9.5 4.8 7.3 9.5 1.6 1 1 0 1 1 1 0 Double zinc ribbon TackOD1 PF18551.1 EKX44380.1 - 2.1 8.0 8.7 8.7 6.0 1.7 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 zinc_ribbon_4 PF13717.6 EKX44380.1 - 7.1 6.6 8.2 25 4.9 0.1 3.9 4 0 0 4 4 4 0 zinc-ribbon domain Pput2613-deam PF14427.6 EKX44380.1 - 8.8 6.3 7.2 7.9 6.4 0.3 3.0 1 1 0 2 2 2 0 Pput_2613-like deaminase Ank_2 PF12796.7 EKX44381.1 - 2.1e-08 34.6 0.0 2.7e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX44381.1 - 1.1e-07 32.3 0.1 2.1e-07 31.4 0.1 1.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX44381.1 - 1.3e-07 31.8 0.0 3.1e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EKX44381.1 - 9.9e-07 28.9 0.1 2.9e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX44381.1 - 2.3e-05 24.4 0.0 0.0014 18.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Pkinase PF00069.25 EKX44382.1 - 1.1e-48 165.9 0.0 1.9e-48 165.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX44382.1 - 3.9e-32 111.5 0.0 7.3e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX44382.1 - 0.0011 17.8 1.2 0.081 11.7 0.0 2.6 3 0 0 3 3 3 2 Fungal protein kinase DUF1633 PF07794.11 EKX44382.1 - 0.0057 14.9 0.1 0.0078 14.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1633) Kdo PF06293.14 EKX44382.1 - 0.068 12.5 0.0 0.4 10.0 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 EKX44382.1 - 0.11 12.6 0.1 0.49 10.6 0.0 1.9 2 0 0 2 2 2 0 ABC1 family Kinase-like PF14531.6 EKX44382.1 - 0.14 11.5 0.0 0.3 10.3 0.0 1.5 1 0 0 1 1 1 0 Kinase-like HATPase_c_3 PF13589.6 EKX44383.1 - 4.2e-09 36.3 0.0 1.4e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EKX44383.1 - 0.0014 19.1 0.0 0.0055 17.2 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BAH PF01426.18 EKX44383.1 - 0.079 12.8 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 BAH domain SPX PF03105.19 EKX44385.1 - 0.41 10.5 3.1 0.51 10.2 3.1 1.2 1 0 0 1 1 1 0 SPX domain SR-25 PF10500.9 EKX44385.1 - 3.1 7.3 14.1 1.5 8.4 11.7 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RabGAP-TBC PF00566.18 EKX44386.1 - 3.8e-43 147.6 0.3 4.5e-43 147.4 0.3 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain adh_short PF00106.25 EKX44387.1 - 8.5e-30 103.7 0.9 3.8e-27 95.0 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EKX44387.1 - 8.8e-18 64.7 0.3 1.6e-17 63.8 0.1 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX44387.1 - 3.1e-06 27.2 0.2 6.9e-06 26.1 0.2 1.5 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 EKX44387.1 - 0.046 13.1 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EKX44387.1 - 0.047 13.6 0.1 0.098 12.5 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 EKX44387.1 - 0.32 11.0 1.6 0.48 10.4 0.1 2.0 2 1 0 2 2 2 0 Zinc-binding dehydrogenase TSNAXIP1_N PF15739.5 EKX44389.1 - 0.00017 22.0 3.4 0.00017 22.0 3.4 2.7 1 1 1 2 2 2 1 Translin-associated factor X-interacting N-terminus SAM_3 PF18016.1 EKX44390.1 - 0.098 12.5 0.3 0.7 9.7 0.0 2.2 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) HAD_2 PF13419.6 EKX44390.1 - 0.11 12.6 0.3 0.16 12.1 0.3 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase IZUMO PF15005.6 EKX44390.1 - 0.18 12.3 4.1 0.11 13.0 0.7 2.2 2 1 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated GCD14 PF08704.10 EKX44390.1 - 0.21 11.2 2.4 0.67 9.6 2.3 1.8 1 1 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Peptidase_S15 PF02129.18 EKX44390.1 - 1.6 8.2 5.3 3.9 7.0 5.3 1.6 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Ribosomal_S8e PF01201.22 EKX44390.1 - 2.3 8.4 5.4 6.8 6.9 5.4 1.7 1 1 0 1 1 1 0 Ribosomal protein S8e A_deamin PF02137.18 EKX44391.1 - 9.8e-31 107.4 0.3 1.2e-30 107.1 0.3 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Acetyltransf_CG PF14542.6 EKX44392.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.5 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase SURF2 PF05477.11 EKX44393.1 - 1.8e-33 116.2 1.5 2e-33 116.1 1.5 1.0 1 0 0 1 1 1 1 Surfeit locus protein 2 (SURF2) IL6Ra-bind PF09240.10 EKX44393.1 - 0.016 15.6 0.1 0.074 13.5 0.0 1.8 1 1 1 2 2 2 0 Interleukin-6 receptor alpha chain, binding DUF2866 PF11065.8 EKX44393.1 - 0.096 12.7 0.0 8.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2866) Pkinase PF00069.25 EKX44394.1 - 3.7e-68 229.7 0.0 4.2e-68 229.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX44394.1 - 1.2e-43 149.3 0.0 1.5e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX44394.1 - 3.8e-10 39.5 0.0 9.9e-08 31.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EKX44394.1 - 1.6e-06 27.2 0.0 2.2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EKX44394.1 - 0.0023 17.3 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX44394.1 - 0.007 16.3 0.0 0.016 15.2 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EKX44394.1 - 0.031 13.8 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL VitD-bind_III PF09164.10 EKX44394.1 - 0.13 12.3 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Vitamin D binding protein, domain III CobA_CobO_BtuR PF02572.15 EKX44394.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Choline_kinase PF01633.20 EKX44394.1 - 0.16 11.5 0.0 0.49 10.0 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Aminotran_5 PF00266.19 EKX44396.1 - 2.5e-29 102.4 0.1 1.1e-14 54.2 0.0 4.1 2 1 1 3 3 3 3 Aminotransferase class-V Crystall_3 PF08964.10 EKX44397.1 - 0.023 14.8 0.2 0.11 12.7 0.2 2.2 1 0 0 1 1 1 0 Beta/Gamma crystallin Clat_adaptor_s PF01217.20 EKX44398.1 - 8e-55 184.7 3.4 9e-55 184.5 3.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Glyco_transf_41 PF13844.6 EKX44399.1 - 2.3e-84 283.5 0.0 7.8e-45 153.2 0.0 2.3 1 1 1 2 2 2 2 Glycosyl transferase family 41 Nucleotid_trans PF03407.16 EKX44399.1 - 5.9e-36 124.4 0.1 1.1e-35 123.6 0.1 1.5 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase TPR_1 PF00515.28 EKX44399.1 - 2.5e-18 65.1 5.9 0.003 17.3 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 EKX44399.1 - 8.9e-18 63.0 3.0 0.0028 17.7 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX44399.1 - 9.1e-17 59.8 9.8 0.00065 19.6 3.1 6.6 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 EKX44399.1 - 3.5e-12 45.8 0.2 0.0037 16.9 1.0 5.3 4 2 2 6 6 6 3 TPR repeat TPR_17 PF13431.6 EKX44399.1 - 7e-11 41.7 1.4 0.027 14.9 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX44399.1 - 5.1e-10 39.5 5.7 0.0036 17.6 2.8 4.7 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX44399.1 - 7.1e-08 33.0 10.9 0.0046 17.6 0.1 4.0 3 1 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX44399.1 - 1e-07 32.2 9.8 0.011 16.5 3.9 5.9 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX44399.1 - 1.2e-07 31.4 8.5 0.026 14.4 0.0 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX44399.1 - 4.5e-07 29.4 2.2 0.85 9.8 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX44399.1 - 0.00011 22.7 9.5 0.046 14.2 1.6 4.3 4 1 1 5 5 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX44399.1 - 0.00053 20.2 0.5 0.0021 18.2 0.1 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EKX44399.1 - 0.0022 18.1 2.5 3.9 7.7 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 EKX44399.1 - 0.0058 17.1 6.3 0.31 11.8 0.0 4.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX44399.1 - 0.089 13.5 3.7 11 6.9 1.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Collagen PF01391.18 EKX44400.1 - 9.1e-31 105.4 122.4 1.2e-09 37.8 34.4 4.2 1 1 3 4 4 4 4 Collagen triple helix repeat (20 copies) FH2 PF02181.23 EKX44400.1 - 0.023 13.8 0.1 0.032 13.4 0.1 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain DUF4472 PF14739.6 EKX44400.1 - 0.04 14.7 1.3 0.069 13.9 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) TPR_MLP1_2 PF07926.12 EKX44400.1 - 0.14 12.2 3.7 0.19 11.8 3.7 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein ABC_tran_CTD PF16326.5 EKX44400.1 - 0.14 12.4 1.6 0.2 11.9 1.6 1.2 1 0 0 1 1 1 0 ABC transporter C-terminal domain Ribosomal_S26e PF01283.19 EKX44401.1 - 4.1e-52 175.2 6.3 4.9e-52 174.9 6.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Laminin_EGF PF00053.24 EKX44402.1 - 1.3e-22 79.7 141.1 0.0016 18.6 9.8 10.4 1 1 9 10 10 10 10 Laminin EGF domain EGF_2 PF07974.13 EKX44402.1 - 2.5e-15 56.5 159.0 0.096 13.1 3.9 11.7 9 5 0 9 9 9 9 EGF-like domain PAS_6 PF08348.11 EKX44402.1 - 1.8e-08 34.3 0.0 14 5.6 0.0 5.6 5 0 0 5 5 5 4 YheO-like PAS domain DSL PF01414.19 EKX44402.1 - 1.2e-06 28.6 152.3 0.027 14.8 15.1 9.3 5 4 0 9 9 9 5 Delta serrate ligand PhnA_Zn_Ribbon PF08274.12 EKX44402.1 - 3.5e-05 23.6 6.3 49 4.0 0.0 6.5 5 0 0 5 5 5 0 PhnA Zinc-Ribbon EGF PF00008.27 EKX44402.1 - 7.2 7.0 115.3 8.4 6.8 8.6 10.5 9 0 0 9 9 9 0 EGF-like domain Ephrin_rec_like PF07699.13 EKX44403.1 - 1.3e-34 117.7 70.4 3.4e-11 42.7 9.6 6.6 4 2 2 6 6 6 6 Putative ephrin-receptor like NCD3G PF07562.14 EKX44403.1 - 2.3e-07 30.7 58.9 0.027 14.4 8.9 6.2 5 1 0 6 6 6 5 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX44403.1 - 0.00052 20.3 61.7 0.01 16.2 0.7 9.4 1 1 8 10 10 10 6 TNFR/NGFR cysteine-rich region VSP PF03302.13 EKX44403.1 - 0.14 11.0 60.9 3.8 6.3 25.2 3.3 1 1 2 3 3 3 0 Giardia variant-specific surface protein Kinesin PF00225.23 EKX44405.1 - 1.5e-101 339.7 2.2 1.5e-101 339.7 2.2 1.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EKX44405.1 - 8e-26 90.8 1.9 2.6e-25 89.1 0.1 2.6 3 0 0 3 3 3 1 Microtubule binding Prok-TraM PF09228.10 EKX44405.1 - 0.036 14.4 0.2 0.098 13.0 0.2 1.7 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM DUF2164 PF09932.9 EKX44405.1 - 0.037 14.1 0.5 0.11 12.5 0.5 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2164) DUF2207 PF09972.9 EKX44406.1 - 0.23 10.2 0.0 0.35 9.6 0.0 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) T2SSF PF00482.23 EKX44406.1 - 0.3 11.0 3.5 0.48 10.4 0.3 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F OppC_N PF12911.7 EKX44406.1 - 2.8 8.0 10.2 1.2 9.1 0.8 2.3 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF3084 PF11283.8 EKX44406.1 - 5.5 7.0 7.3 0.17 11.9 1.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3084) RMI2 PF16100.5 EKX44407.1 - 9.5e-14 51.3 0.2 1.2e-13 51.0 0.2 1.2 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 tRNA_anti-codon PF01336.25 EKX44407.1 - 0.0012 18.8 0.1 0.0017 18.3 0.1 1.2 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Asp PF00026.23 EKX44408.1 - 2.1e-27 96.4 0.0 3.3e-17 62.9 0.0 2.7 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EKX44408.1 - 4.1e-07 30.4 0.1 0.00035 20.9 0.0 2.3 2 0 0 2 2 2 2 Xylanase inhibitor N-terminal CDP-OH_P_transf PF01066.21 EKX44409.1 - 9.1e-17 61.6 0.3 9.1e-17 61.6 0.3 2.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase His_Phos_1 PF00300.22 EKX44410.1 - 4.2e-37 127.7 0.0 5.2e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DDHD PF02862.17 EKX44412.1 - 3.7e-25 89.4 0.1 6.6e-25 88.6 0.1 1.4 1 0 0 1 1 1 1 DDHD domain BIR PF00653.21 EKX44412.1 - 2.4e-18 66.6 3.6 4.9e-18 65.5 3.6 1.6 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain DUF676 PF05057.14 EKX44412.1 - 0.032 13.7 0.1 6.1 6.3 0.0 2.3 2 0 0 2 2 2 0 Putative serine esterase (DUF676) YscK PF06578.12 EKX44412.1 - 0.055 13.0 0.0 0.27 10.7 0.0 1.9 2 0 0 2 2 2 0 YOP proteins translocation protein K (YscK) Abhydrolase_8 PF06259.12 EKX44412.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Clat_adaptor_s PF01217.20 EKX44413.1 - 1.2e-49 167.9 0.8 1.5e-49 167.6 0.8 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TIC20 PF16166.5 EKX44415.1 - 7.3e-23 81.3 4.2 8.6e-23 81.0 4.2 1.1 1 0 0 1 1 1 1 Chloroplast import apparatus Tic20-like DUF2070 PF09843.9 EKX44415.1 - 2.8 6.1 7.0 3.7 5.7 7.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) HTH_33 PF13592.6 EKX44416.1 - 0.0056 16.3 0.4 0.086 12.5 0.0 2.6 3 0 0 3 3 3 1 Winged helix-turn helix RPA_C PF08784.11 EKX44416.1 - 0.0082 16.8 0.0 0.023 15.3 0.0 1.7 2 0 0 2 2 2 1 Replication protein A C terminal PqqD PF05402.12 EKX44416.1 - 0.0096 16.2 0.0 0.048 14.0 0.0 2.1 2 0 0 2 2 2 1 Coenzyme PQQ synthesis protein D (PqqD) DUF5457 PF17540.2 EKX44416.1 - 0.035 14.2 0.2 0.07 13.2 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5457) Stork_head PF10264.9 EKX44416.1 - 0.052 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain G_glu_transpept PF01019.21 EKX44417.1 - 4.8e-72 243.4 0.1 5.9e-37 127.6 0.0 2.2 1 1 1 2 2 2 2 Gamma-glutamyltranspeptidase Ion_trans PF00520.31 EKX44419.1 - 6.2e-14 51.8 9.4 1.6e-06 27.6 0.2 2.4 2 0 0 2 2 2 2 Ion transport protein cNMP_binding PF00027.29 EKX44419.1 - 1e-11 44.8 0.0 1.8e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EKX44419.1 - 1.3e-09 37.9 0.8 1.3e-09 37.9 0.8 2.1 2 0 0 2 2 2 1 Ion channel Oxidored_q2 PF00420.24 EKX44419.1 - 0.039 13.6 0.5 0.11 12.2 0.5 1.7 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L MMS1_N PF10433.9 EKX44419.1 - 0.098 11.3 0.0 0.18 10.4 0.0 1.4 1 0 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term HAD_SAK_2 PF18143.1 EKX44420.1 - 4.7e-20 72.3 0.0 7e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 HAD domain in Swiss Army Knife RNA repair proteins Apt1 PF10351.9 EKX44420.1 - 0.00074 18.5 3.6 0.00074 18.5 3.6 1.1 1 0 0 1 1 1 1 Golgi-body localisation protein domain MID_MedPIWI PF18296.1 EKX44420.1 - 0.075 12.8 6.8 4.5 7.0 5.3 2.2 2 0 0 2 2 2 0 MID domain of medPIWI DUF515 PF04415.12 EKX44420.1 - 0.73 8.2 32.9 1 7.7 32.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) LRRFIP PF09738.9 EKX44420.1 - 1 8.8 6.2 1.7 8.1 6.2 1.3 1 0 0 1 1 1 0 LRRFIP family DUF5383 PF17355.2 EKX44420.1 - 2.2 8.7 5.6 0.75 10.2 2.4 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5383) Macoilin PF09726.9 EKX44420.1 - 2.2 6.7 16.9 3.1 6.3 16.9 1.1 1 0 0 1 1 1 0 Macoilin family Shisa PF13908.6 EKX44420.1 - 2.9 8.1 11.1 0.65 10.2 7.7 1.6 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator SSP160 PF06933.11 EKX44420.1 - 3.2 5.8 36.1 5.3 5.1 36.1 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 WW PF00397.26 EKX44421.1 - 5e-19 68.1 2.7 9.3e-09 35.2 0.2 2.4 2 0 0 2 2 2 2 WW domain PIN_4 PF13638.6 EKX44421.1 - 1.5e-12 47.9 0.0 3.5e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 PIN domain BRCT PF00533.26 EKX44421.1 - 1.1e-10 41.8 0.0 4.6e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EKX44421.1 - 8.5e-09 35.7 0.0 1.9e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PIN_12 PF16289.5 EKX44421.1 - 7e-05 23.4 0.0 0.00018 22.1 0.0 1.7 1 0 0 1 1 1 1 PIN domain RTT107_BRCT_5 PF16770.5 EKX44421.1 - 0.015 15.2 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain PIN_9 PF18477.1 EKX44421.1 - 0.021 15.1 0.0 2.3 8.6 0.0 2.9 3 0 0 3 3 3 0 PIN like domain RecG_N PF17190.4 EKX44421.1 - 0.035 14.8 0.1 0.12 13.1 0.1 1.9 1 0 0 1 1 1 0 RecG N-terminal helical domain PTCB-BRCT PF12738.7 EKX44421.1 - 0.075 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain YadA_head PF05658.14 EKX44421.1 - 2 8.9 3.5 1.1 9.7 0.4 2.1 2 0 0 2 2 2 0 Head domain of trimeric autotransporter adhesin Pkinase PF00069.25 EKX44422.1 - 3.3e-46 157.8 0.0 4.4e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX44422.1 - 1.6e-38 132.5 0.0 2e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX44422.1 - 0.0052 16.1 0.0 0.021 14.1 0.0 1.7 1 1 0 2 2 2 1 Kinase-like ABC1 PF03109.16 EKX44422.1 - 0.0063 16.7 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 ABC1 family HTH_35 PF13693.6 EKX44423.1 - 0.033 14.2 2.2 0.037 14.1 0.3 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_26 PF13443.6 EKX44423.1 - 0.077 13.4 0.7 0.77 10.2 0.1 2.6 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain AKNA PF12443.8 EKX44424.1 - 0.049 14.3 2.7 11 6.7 0.0 3.5 3 1 0 3 3 3 0 AT-hook-containing transcription factor FtsK_SpoIIIE PF01580.18 EKX44424.1 - 0.075 12.4 1.2 0.17 11.2 0.1 2.1 2 1 1 3 3 3 0 FtsK/SpoIIIE family Halogen_Hydrol PF10112.9 EKX44424.1 - 0.24 11.4 3.3 0.89 9.5 0.2 2.4 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF2524 PF10732.9 EKX44424.1 - 0.34 11.3 9.2 0.27 11.6 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2524) HrpB7 PF09486.10 EKX44424.1 - 0.5 10.7 9.0 1.8 8.9 0.4 2.6 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) TPR_MLP1_2 PF07926.12 EKX44424.1 - 1.4 9.0 21.7 1.2 9.2 6.5 3.2 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein UvrD_C PF13361.6 EKX44424.1 - 1.4 8.2 11.9 1.4 8.3 4.9 2.1 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain DUF5344 PF17279.2 EKX44424.1 - 1.8 9.2 11.2 2.1 9.0 4.5 2.8 3 0 0 3 3 2 0 Family of unknown function (DUF5344) KxDL PF10241.9 EKX44424.1 - 2 8.7 6.6 1.8 8.9 0.2 3.1 2 1 1 3 3 3 0 Uncharacterized conserved protein Lebercilin PF15619.6 EKX44424.1 - 2.8 7.6 13.6 4.3 6.9 0.5 2.6 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF5082 PF16888.5 EKX44424.1 - 4 7.7 11.5 0.57 10.5 0.6 3.6 3 2 0 3 3 3 0 Domain of unknown function (DUF5082) HAGH_C PF16123.5 EKX44426.1 - 8e-09 35.9 0.1 0.0016 18.9 0.0 2.3 1 1 1 2 2 2 2 Hydroxyacylglutathione hydrolase C-terminus Thioredoxin PF00085.20 EKX44429.1 - 6.3e-26 90.4 0.1 1.2e-19 70.2 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EKX44429.1 - 1.2e-12 48.1 7.9 2.9e-09 37.1 1.4 4.3 3 1 1 4 4 4 2 Thioredoxin-like domain Calsequestrin PF01216.17 EKX44429.1 - 4e-07 29.4 3.7 8.3e-06 25.1 3.0 2.2 2 0 0 2 2 2 1 Calsequestrin AhpC-TSA PF00578.21 EKX44429.1 - 0.0095 15.9 0.3 0.26 11.2 0.1 2.6 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_2 PF13098.6 EKX44429.1 - 0.03 14.7 4.0 3.9 8.0 0.1 4.2 3 1 1 4 4 4 0 Thioredoxin-like domain ERp29_N PF07912.13 EKX44429.1 - 0.064 13.4 1.0 7.9 6.6 0.0 3.2 3 1 0 3 3 3 0 ERp29, N-terminal domain Thioredoxin_8 PF13905.6 EKX44429.1 - 0.11 12.8 0.4 8.2 6.8 0.0 3.6 3 1 1 4 4 4 0 Thioredoxin-like Ion_trans PF00520.31 EKX44430.1 - 4.8e-198 654.8 83.0 2.1e-53 181.1 11.5 4.2 4 0 0 4 4 4 4 Ion transport protein GPHH PF16905.5 EKX44430.1 - 1.9e-10 40.3 0.0 4e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 EKX44430.1 - 2.8e-09 36.1 77.9 0.00041 19.1 3.4 9.7 7 3 2 9 9 9 9 Polycystin cation channel Yip1 PF04893.17 EKX44431.1 - 5.8e-05 22.9 0.2 7.5e-05 22.5 0.2 1.1 1 0 0 1 1 1 1 Yip1 domain Glucos_trans_II PF14264.6 EKX44431.1 - 0.0042 16.5 3.6 0.0056 16.1 3.6 1.1 1 0 0 1 1 1 1 Glucosyl transferase GtrII DUF1129 PF06570.11 EKX44431.1 - 0.04 13.4 3.2 1.5 8.3 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) DUF1772 PF08592.11 EKX44431.1 - 0.078 13.3 1.9 0.42 10.9 1.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) DUF2842 PF11003.8 EKX44431.1 - 0.11 12.8 0.2 0.11 12.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2842) DUF2206 PF09971.9 EKX44431.1 - 0.68 8.6 5.1 0.12 11.0 0.7 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2206) PAP2 PF01569.21 EKX44431.1 - 1.1 9.1 6.2 0.62 9.8 0.5 2.2 1 1 1 2 2 2 0 PAP2 superfamily DUF2207 PF09972.9 EKX44431.1 - 2.9 6.6 7.8 55 2.3 7.9 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Lung_7-TM_R PF06814.13 EKX44431.1 - 3.8 6.7 8.1 2.5 7.3 0.2 2.8 1 1 2 3 3 3 0 Lung seven transmembrane receptor Peptidase_M16 PF00675.20 EKX44432.1 - 1e-32 113.1 0.1 1.5e-32 112.6 0.1 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EKX44432.1 - 1.8e-14 54.1 0.0 3.7e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16_C PF05193.21 EKX44433.1 - 2.8e-06 27.5 0.0 5.1e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Abhydrolase_2 PF02230.16 EKX44434.1 - 1.6e-66 224.2 0.0 1.7e-66 224.1 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 EKX44434.1 - 1.1e-05 25.2 0.0 4.6e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EKX44434.1 - 6.2e-05 23.7 0.0 6.9e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EKX44434.1 - 0.00055 19.3 0.0 0.091 12.0 0.1 2.7 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 EKX44434.1 - 0.0041 16.8 0.0 0.0058 16.3 0.0 1.3 1 1 0 1 1 1 1 Putative esterase DLH PF01738.18 EKX44434.1 - 0.0051 16.4 0.0 0.0069 16.0 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF2974 PF11187.8 EKX44434.1 - 0.012 15.2 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 EKX44434.1 - 0.015 14.9 0.1 0.029 14.0 0.1 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 EKX44434.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Cutinase PF01083.22 EKX44434.1 - 0.15 12.0 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Cutinase Tubulin PF00091.25 EKX44435.1 - 4.3e-52 177.2 0.0 2.5e-51 174.7 0.0 1.9 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.9 EKX44435.1 - 0.0082 16.4 0.0 0.016 15.5 0.0 1.5 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 EKX44435.1 - 0.099 11.8 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Tubulin like DUF1819 PF08849.11 EKX44436.1 - 0.081 12.7 0.2 0.15 11.9 0.2 1.3 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) Pyr_redox_2 PF07992.14 EKX44437.1 - 1.1e-21 77.4 0.1 6.3e-16 58.4 0.0 1.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EKX44437.1 - 3.6e-08 33.8 1.6 0.004 17.7 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EKX44437.1 - 5.6e-05 22.4 0.1 0.28 10.3 0.0 2.6 2 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DUF1188 PF06690.11 EKX44437.1 - 5.7e-05 22.8 0.0 0.0015 18.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1188) DAO PF01266.24 EKX44437.1 - 0.00071 19.3 0.6 0.08 12.5 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EKX44437.1 - 0.0012 18.2 0.3 0.041 13.1 0.0 2.1 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EKX44437.1 - 0.0021 17.4 2.7 0.028 13.7 0.0 2.7 2 1 1 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 EKX44437.1 - 0.005 17.0 1.8 0.27 11.5 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Eno-Rase_NADH_b PF12242.8 EKX44437.1 - 0.011 15.4 0.1 2.5 7.9 0.0 2.4 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Thi4 PF01946.17 EKX44437.1 - 0.012 14.9 0.0 0.11 11.7 0.0 2.0 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.21 EKX44437.1 - 0.012 14.9 0.0 0.52 9.6 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 EKX44437.1 - 0.049 13.7 0.2 2 8.5 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 EKX44437.1 - 0.072 12.2 0.2 1.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EKX44437.1 - 0.1 11.6 0.4 4 6.4 0.4 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein TrkA_N PF02254.18 EKX44437.1 - 0.12 12.6 0.3 9.9 6.5 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain Snf7 PF03357.21 EKX44438.1 - 1.5e-33 115.8 18.3 1.9e-33 115.5 18.3 1.1 1 0 0 1 1 1 1 Snf7 HTH_6 PF01418.17 EKX44438.1 - 0.0063 16.5 0.2 0.013 15.4 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family Prenyltransf PF01255.19 EKX44438.1 - 0.1 12.1 3.6 0.049 13.1 1.4 1.5 1 1 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Cas9_Topo PF17894.1 EKX44438.1 - 0.13 12.3 0.2 0.27 11.3 0.2 1.6 1 0 0 1 1 1 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 Herpes_UL73 PF03554.13 EKX44438.1 - 0.23 11.5 0.0 0.35 10.9 0.0 1.3 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein CdvA PF18822.1 EKX44438.1 - 0.35 10.7 11.3 0.54 10.1 3.5 2.7 2 1 1 3 3 3 0 CdvA-like coiled-coil domain PIN_8 PF18476.1 EKX44438.1 - 2.5 7.9 8.9 25 4.7 8.9 2.0 1 1 0 1 1 1 0 PIN like domain Ribosomal_S20p PF01649.18 EKX44438.1 - 5.2 7.8 8.7 0.37 11.4 1.9 2.2 2 1 0 2 2 2 0 Ribosomal protein S20 Abhydrolase_1 PF00561.20 EKX44439.1 - 2.3e-23 83.2 0.2 4.9e-18 65.7 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EKX44439.1 - 6.4e-10 40.0 0.0 2.7e-09 38.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EKX44439.1 - 1.3e-07 31.1 0.0 6.7e-05 22.3 0.0 2.3 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Ndr PF03096.14 EKX44439.1 - 1.6e-05 23.8 0.0 0.00017 20.4 0.0 2.1 2 0 0 2 2 2 1 Ndr family Abhydrolase_5 PF12695.7 EKX44439.1 - 0.047 13.5 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family UbiA PF01040.18 EKX44440.1 - 2.8e-25 89.1 11.7 3.6e-25 88.7 11.7 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF2160 PF09928.9 EKX44440.1 - 0.18 12.2 0.2 0.18 12.2 0.2 2.8 3 0 0 3 3 3 0 Predicted small integral membrane protein (DUF2160) adh_short PF00106.25 EKX44441.1 - 4.9e-35 120.8 0.1 6.3e-35 120.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EKX44441.1 - 6.1e-23 81.6 0.2 7.3e-23 81.3 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX44441.1 - 0.025 14.5 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 KR domain HECT PF00632.25 EKX44444.1 - 2.8e-96 322.6 0.0 4.1e-96 322.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 EKX44445.1 - 5.1e-12 45.7 1.8 1e-11 44.7 1.8 1.6 1 0 0 1 1 1 1 WW domain SH3_1 PF00018.28 EKX44445.1 - 1.7e-10 40.4 0.2 3.7e-10 39.3 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EKX44445.1 - 1.2e-07 31.5 0.0 2.8e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EKX44445.1 - 1.3e-05 24.8 0.0 3.2e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PDZ PF00595.24 EKX44445.1 - 0.00023 21.4 0.1 0.00059 20.1 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX44445.1 - 0.00097 19.4 0.7 0.004 17.5 0.1 2.5 3 0 0 3 3 1 1 PDZ domain PDZ_6 PF17820.1 EKX44445.1 - 0.0036 17.1 0.3 0.0095 15.8 0.3 1.8 1 0 0 1 1 1 1 PDZ domain TMF_TATA_bd PF12325.8 EKX44445.1 - 0.0095 16.2 6.7 0.0095 16.2 6.7 3.2 3 0 0 3 3 3 1 TATA element modulatory factor 1 TATA binding DUF812 PF05667.11 EKX44445.1 - 0.051 12.5 14.2 0.11 11.4 14.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Golgin_A5 PF09787.9 EKX44445.1 - 0.079 12.4 15.9 0.19 11.2 15.9 1.7 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF5082 PF16888.5 EKX44445.1 - 0.22 11.8 12.3 0.55 10.5 12.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) GPS2_interact PF15784.5 EKX44445.1 - 0.35 11.4 7.6 1.5 9.3 7.6 2.0 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DUF16 PF01519.16 EKX44445.1 - 0.37 11.3 6.4 0.23 11.9 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.12 EKX44445.1 - 0.46 11.1 11.2 0.29 11.8 0.3 2.9 2 0 0 2 2 2 0 SlyX DUF4201 PF13870.6 EKX44445.1 - 1.1 9.0 15.5 0.36 10.5 7.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) ALMT PF11744.8 EKX44445.1 - 1.4 7.7 11.5 1.2 7.9 9.0 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter TMCO5 PF14992.6 EKX44445.1 - 1.4 8.4 14.4 3.2 7.3 14.4 1.5 1 0 0 1 1 1 0 TMCO5 family Cluap1 PF10234.9 EKX44445.1 - 1.7 8.0 12.0 3.2 7.1 12.0 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 BST2 PF16716.5 EKX44445.1 - 2.1 9.0 13.8 2.6 8.7 8.8 2.7 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 CCDC53 PF10152.9 EKX44445.1 - 2.2 8.7 9.4 0.16 12.4 3.5 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Prefoldin_2 PF01920.20 EKX44445.1 - 2.5 8.1 13.6 0.23 11.5 5.7 2.9 2 1 0 2 2 2 0 Prefoldin subunit Cgr1 PF03879.14 EKX44446.1 - 2.2e-13 50.5 23.6 2.9e-13 50.1 23.6 1.1 1 0 0 1 1 1 1 Cgr1 family DUF4718 PF15842.5 EKX44446.1 - 1.2 9.0 5.8 1.4 8.7 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Acetyltransf_1 PF00583.25 EKX44448.1 - 2.7e-15 56.6 0.0 3.5e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EKX44448.1 - 1.6e-09 37.8 0.1 7.2e-09 35.7 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EKX44448.1 - 3.6e-09 36.9 0.0 6.6e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EKX44448.1 - 1.4e-05 25.0 0.0 2.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EKX44448.1 - 0.0046 17.1 0.0 0.0074 16.4 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 EKX44448.1 - 0.0076 16.3 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EKX44448.1 - 0.024 14.6 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_3 PF13302.7 EKX44448.1 - 0.078 13.6 0.0 0.12 13.0 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EKX44448.1 - 0.19 11.9 0.0 0.61 10.2 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Kelch_5 PF13854.6 EKX44449.1 - 4.8e-31 106.2 46.7 0.00073 19.5 0.2 17.5 18 0 0 18 18 18 8 Kelch motif Kelch_4 PF13418.6 EKX44449.1 - 6e-26 90.2 42.9 6e-05 23.0 0.1 13.9 14 1 0 14 14 14 8 Galactose oxidase, central domain Filamin PF00630.19 EKX44449.1 - 1.6e-20 73.8 0.0 3.4e-07 31.0 0.0 4.2 3 1 0 3 3 3 3 Filamin/ABP280 repeat Kelch_3 PF13415.6 EKX44449.1 - 5e-17 61.7 54.3 2.7e-05 24.3 0.1 16.3 19 0 0 19 19 18 6 Galactose oxidase, central domain Kelch_6 PF13964.6 EKX44449.1 - 1.3e-14 53.9 26.3 0.1 12.9 0.1 13.1 12 0 0 12 12 12 4 Kelch motif Kelch_1 PF01344.25 EKX44449.1 - 1.1e-08 34.6 24.2 0.028 14.0 0.3 11.1 11 0 0 11 11 11 3 Kelch motif Kelch_2 PF07646.15 EKX44449.1 - 6.5e-07 29.1 28.6 0.0089 16.0 0.1 11.3 11 0 0 11 11 11 3 Kelch motif Invasin_D3 PF09134.10 EKX44449.1 - 9.1e-05 22.7 2.7 0.024 14.9 0.0 4.5 4 0 0 4 4 4 1 Invasin, domain 3 Laminin_G_3 PF13385.6 EKX44449.1 - 0.011 15.9 1.6 0.12 12.5 0.0 3.3 2 1 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily HYR PF02494.16 EKX44449.1 - 0.15 12.4 0.6 0.55 10.6 0.2 2.2 2 0 0 2 2 2 0 HYR domain Big_1 PF02369.16 EKX44449.1 - 0.18 11.8 0.0 0.18 11.8 0.0 4.5 5 0 0 5 5 4 0 Bacterial Ig-like domain (group 1) Hydrolase_like PF13242.6 EKX44451.1 - 2.5e-10 40.3 0.0 5.4e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EKX44451.1 - 8.4e-10 39.3 0.0 7.3e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EKX44451.1 - 2.1e-08 34.4 0.0 5.1e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase AA_kinase PF00696.28 EKX44451.1 - 0.0061 16.2 0.2 0.008 15.8 0.2 1.4 1 1 0 1 1 1 1 Amino acid kinase family Hydrolase_6 PF13344.6 EKX44451.1 - 0.0087 16.2 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_SAK_2 PF18143.1 EKX44451.1 - 0.024 15.0 0.0 0.031 14.6 0.0 1.2 1 0 0 1 1 1 0 HAD domain in Swiss Army Knife RNA repair proteins DUF5575 PF17738.1 EKX44451.1 - 0.072 12.1 0.0 0.089 11.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5575) SAP PF02037.27 EKX44452.1 - 1e-05 25.1 3.2 1e-05 25.1 3.2 2.0 2 0 0 2 2 2 1 SAP domain Complex1_LYR PF05347.15 EKX44452.1 - 2.3e-05 24.3 0.4 2.3e-05 24.3 0.4 2.1 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 EKX44452.1 - 0.0067 17.0 0.1 0.022 15.4 0.1 1.9 1 1 0 1 1 1 1 Complex1_LYR-like PIG-L PF02585.17 EKX44452.1 - 0.36 11.5 2.8 0.64 10.6 0.2 2.1 2 0 0 2 2 2 0 GlcNAc-PI de-N-acetylase Complex1_LYR_2 PF13233.6 EKX44452.1 - 0.59 10.9 4.5 0.38 11.5 1.2 2.3 2 1 0 2 2 2 0 Complex1_LYR-like LZ_Tnp_IS66 PF13007.7 EKX44452.1 - 3.2 8.6 8.7 2.1 9.2 3.0 2.5 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain VPS11_C PF12451.8 EKX44453.1 - 0.39 11.0 2.6 1.1 9.6 0.1 2.7 3 0 0 3 3 3 0 Vacuolar protein sorting protein 11 C terminal zf-RING_2 PF13639.6 EKX44454.1 - 3.8e-07 30.3 11.0 6.9e-07 29.5 11.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX44454.1 - 0.0032 17.3 12.4 0.012 15.4 12.6 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.6 EKX44454.1 - 0.0045 17.1 2.6 0.011 15.8 2.6 1.7 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-RING_11 PF17123.5 EKX44454.1 - 0.005 16.5 8.7 0.005 16.5 8.7 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EKX44454.1 - 0.0061 16.6 9.2 0.02 14.9 5.8 2.4 2 0 0 2 2 2 1 RING-type zinc-finger FYVE_2 PF02318.16 EKX44454.1 - 0.012 15.8 5.7 0.021 15.0 5.7 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C3HC4_3 PF13920.6 EKX44454.1 - 0.013 15.3 8.5 0.024 14.5 8.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EKX44454.1 - 0.031 14.3 3.3 0.069 13.2 3.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H PF13771.6 EKX44454.1 - 0.034 14.4 4.8 0.083 13.1 4.8 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_5 PF14634.6 EKX44454.1 - 0.035 14.1 10.5 0.072 13.1 10.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-4CXXC_R1 PF10497.9 EKX44454.1 - 0.11 12.7 6.8 0.042 14.1 3.9 1.8 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Zn_ribbon_17 PF17120.5 EKX44454.1 - 0.22 11.2 9.4 0.42 10.3 9.4 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 EKX44454.1 - 0.29 11.0 9.3 1.2 9.1 9.7 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 EKX44454.1 - 0.57 10.1 9.6 1.4 8.9 9.6 1.7 1 0 0 1 1 1 0 PHD-finger zf-MIZ PF02891.20 EKX44454.1 - 1.7 8.5 7.6 4.4 7.1 7.6 1.8 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Prok-RING_1 PF14446.6 EKX44454.1 - 2.3 8.2 11.2 1.1 9.2 7.1 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Collagen PF01391.18 EKX44455.1 - 2.3e-17 62.5 52.1 1.5e-09 37.5 27.4 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Ank_2 PF12796.7 EKX44456.1 - 9.7e-16 58.1 0.1 3.4e-11 43.6 0.0 2.0 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX44456.1 - 1.3e-13 50.9 0.1 1.8e-08 34.5 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX44456.1 - 1.2e-10 41.7 0.1 4.4e-07 30.3 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX44456.1 - 2.5e-07 30.8 0.1 0.0028 18.0 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EKX44456.1 - 4.3e-05 23.6 0.0 0.036 14.6 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat RecQ5 PF06959.11 EKX44456.1 - 0.062 13.3 0.8 0.33 10.9 0.3 2.0 2 0 0 2 2 2 0 RecQ helicase protein-like 5 (RecQ5) LPP20 PF02169.16 EKX44456.1 - 0.83 10.0 3.3 1.7 9.0 3.3 1.7 1 1 0 1 1 1 0 LPP20 lipoprotein BBIP10 PF14777.6 EKX44457.1 - 0.058 13.0 0.1 0.27 10.8 0.1 2.1 2 0 0 2 2 2 0 Cilia BBSome complex subunit 10 Imm63 PF15599.6 EKX44457.1 - 0.062 13.7 0.0 0.2 12.1 0.0 1.9 2 0 0 2 2 2 0 Immunity protein 63 DIL PF01843.19 EKX44458.1 - 0.00013 22.1 0.0 0.00051 20.3 0.0 2.1 1 1 0 1 1 1 1 DIL domain FANCI_HD2 PF14680.6 EKX44458.1 - 0.35 10.1 2.9 0.44 9.8 0.0 2.3 2 0 0 2 2 2 0 FANCI helical domain 2 dsrm PF00035.26 EKX44459.1 - 3.5e-06 27.6 0.0 6.3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif LpxD PF04613.14 EKX44459.1 - 0.028 14.2 0.0 0.077 12.8 0.0 1.7 1 0 0 1 1 1 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD Ank_5 PF13857.6 EKX44460.1 - 3.1e-13 49.6 0.1 2.5e-08 34.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX44460.1 - 1.2e-11 45.0 0.0 4.2e-11 43.3 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX44460.1 - 2.2e-10 40.9 0.1 6.3e-07 29.8 0.1 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX44460.1 - 4.6e-07 30.0 0.0 0.0038 17.6 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EKX44460.1 - 8.2e-05 22.7 0.0 0.049 14.2 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Hydrolase_6 PF13344.6 EKX44462.1 - 2.6e-16 59.6 0.0 4.5e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EKX44462.1 - 6.7e-14 51.7 0.0 1.3e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 EKX44462.1 - 4.5e-09 36.6 0.0 6.3e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EKX44462.1 - 2e-07 31.5 0.0 0.019 15.2 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 EKX44462.1 - 0.16 11.5 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) EF-hand_8 PF13833.6 EKX44463.1 - 5.5e-11 42.2 2.1 5.8e-08 32.5 0.1 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 EKX44463.1 - 5.9e-11 42.7 4.2 9.9e-11 41.9 0.4 2.7 2 2 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX44463.1 - 4.3e-10 38.4 1.2 0.00025 20.4 0.2 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX44463.1 - 5.8e-09 35.2 0.5 8.5e-05 22.2 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EKX44463.1 - 9.1e-08 31.3 2.4 0.0023 17.4 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_10 PF14788.6 EKX44463.1 - 4e-05 23.4 1.6 0.0099 15.7 0.1 2.9 2 1 1 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 EKX44463.1 - 0.03 14.6 1.3 0.13 12.6 0.1 2.4 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region MHB PF16525.5 EKX44463.1 - 0.078 13.2 0.0 0.73 10.1 0.0 2.1 2 0 0 2 2 2 0 Haemophore, haem-binding Mito_fiss_reg PF05308.11 EKX44464.1 - 0.023 14.8 0.3 0.023 14.8 0.3 1.9 2 0 0 2 2 2 0 Mitochondrial fission regulator DLEU7 PF15760.5 EKX44464.1 - 3.4 7.1 7.3 0.12 11.9 0.3 2.1 2 1 0 3 3 3 0 Leukemia-associated protein 7 Glyco_hydro_14 PF01373.17 EKX44465.1 - 1.7e-74 251.2 0.0 1.2e-73 248.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 14 SUIM_assoc PF16619.5 EKX44465.1 - 0.86 9.7 10.0 1.7 8.7 10.0 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TruD PF01142.18 EKX44466.1 - 5.2e-59 200.1 0.0 3e-53 181.2 0.0 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Chorismate_bind PF00425.18 EKX44467.1 - 6.6e-61 206.1 0.0 9.5e-61 205.6 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme ATP-cone PF03477.16 EKX44467.1 - 0.083 13.5 0.4 0.18 12.4 0.4 1.6 1 0 0 1 1 1 0 ATP cone domain TPP_enzyme_N PF02776.18 EKX44468.1 - 9e-33 113.3 0.0 1.9e-32 112.2 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M_2 PF16582.5 EKX44468.1 - 1.7e-19 70.4 0.0 2.4e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Middle domain of thiamine pyrophosphate TPP_enzyme_C PF02775.21 EKX44468.1 - 3.4e-06 26.9 0.0 2.1e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Abhydrolase_1 PF00561.20 EKX44469.1 - 1.6e-18 67.3 0.3 5.4e-18 65.6 0.3 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EKX44469.1 - 2.5e-14 54.4 0.0 2.7e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EKX44469.1 - 5.9e-11 42.1 0.0 9.1e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 EKX44469.1 - 9.5e-07 28.7 0.2 2.2e-06 27.5 0.2 1.7 1 1 0 1 1 1 1 Putative esterase Ndr PF03096.14 EKX44469.1 - 8.2e-05 21.4 0.0 0.00011 21.0 0.0 1.2 1 0 0 1 1 1 1 Ndr family Thioesterase PF00975.20 EKX44469.1 - 0.00056 20.1 0.1 0.0012 19.1 0.0 1.6 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.7 EKX44469.1 - 0.0051 16.6 0.0 0.0071 16.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EKX44469.1 - 0.016 15.1 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 EKX44469.1 - 0.044 13.3 0.0 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 EKX44469.1 - 0.1 12.4 0.7 0.13 12.0 0.0 1.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF2048 PF09752.9 EKX44469.1 - 0.1 11.7 0.4 0.26 10.4 0.2 1.6 1 1 1 2 2 2 0 Abhydrolase domain containing 18 DUF726 PF05277.12 EKX44469.1 - 0.19 10.6 0.1 0.27 10.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF726) TPR_1 PF00515.28 EKX44470.1 - 1.9e-63 207.8 22.5 6.7e-08 32.0 0.1 10.5 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_2 PF07719.17 EKX44470.1 - 9.1e-55 178.4 16.8 1e-05 25.2 0.0 10.7 10 0 0 10 10 10 10 Tetratricopeptide repeat Glyco_transf_41 PF13844.6 EKX44470.1 - 6.1e-52 176.6 0.0 6.8e-28 97.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_11 PF13414.6 EKX44470.1 - 1.5e-47 159.0 27.5 2.1e-08 33.7 0.1 11.2 6 2 5 11 11 11 10 TPR repeat TPR_8 PF13181.6 EKX44470.1 - 1.2e-42 140.6 17.8 3e-05 23.9 0.0 10.6 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.6 EKX44470.1 - 5.6e-39 132.3 8.4 6.4e-10 39.2 0.0 9.0 5 2 4 9 9 9 7 Tetratricopeptide repeat TPR_17 PF13431.6 EKX44470.1 - 7.4e-36 120.0 23.5 1.5e-06 28.1 0.1 11.5 10 1 0 11 11 11 6 Tetratricopeptide repeat TPR_7 PF13176.6 EKX44470.1 - 2.3e-29 99.3 2.8 9.6e-05 22.2 0.0 9.1 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_16 PF13432.6 EKX44470.1 - 5e-27 94.3 5.0 0.00031 21.3 0.0 8.4 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 EKX44470.1 - 1.3e-26 91.0 3.1 0.0026 18.5 0.0 10.1 4 1 6 10 10 10 4 Tetratricopeptide repeat TPR_10 PF13374.6 EKX44470.1 - 5.2e-23 80.2 18.8 0.0014 18.5 0.0 10.2 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 EKX44470.1 - 1.1e-19 70.7 12.8 5.5e-08 33.2 0.1 7.0 5 1 1 7 7 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 EKX44470.1 - 1.5e-15 57.0 0.4 0.00015 21.9 0.0 7.7 5 2 4 9 9 9 5 Tetratricopeptide repeat TPR_6 PF13174.6 EKX44470.1 - 1.6e-10 40.9 7.4 0.099 13.3 0.0 9.0 10 0 0 10 10 9 1 Tetratricopeptide repeat TOM20_plant PF06552.12 EKX44470.1 - 3.3e-08 33.5 1.1 0.0001 22.1 0.0 3.7 2 1 1 4 4 4 2 Plant specific mitochondrial import receptor subunit TOM20 TPR_4 PF07721.14 EKX44470.1 - 0.00018 21.8 0.0 6.4 7.7 0.0 5.2 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_3 PF07720.12 EKX44470.1 - 0.00035 20.5 1.3 0.8 9.8 0.2 3.6 3 0 0 3 3 2 2 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 EKX44470.1 - 0.00036 20.1 14.0 0.00076 19.0 0.1 4.0 3 1 1 4 4 4 2 Est1 DNA/RNA binding domain MIT PF04212.18 EKX44470.1 - 0.00044 20.2 9.8 18 5.5 0.1 7.4 6 1 1 7 7 7 0 MIT (microtubule interacting and transport) domain Sel1 PF08238.12 EKX44470.1 - 0.0013 19.3 5.7 2.9 8.7 0.1 5.7 5 1 0 5 5 5 1 Sel1 repeat TPR_MalT PF17874.1 EKX44470.1 - 0.0018 17.7 0.6 5 6.4 0.0 4.0 2 1 2 4 4 4 1 MalT-like TPR region SNAP PF14938.6 EKX44470.1 - 0.0051 16.3 7.0 0.3 10.5 0.3 3.7 3 1 1 4 4 4 1 Soluble NSF attachment protein, SNAP NARP1 PF12569.8 EKX44470.1 - 0.0073 15.3 0.1 6.6 5.5 0.0 3.3 3 1 1 4 4 4 1 NMDA receptor-regulated protein 1 DUF3856 PF12968.7 EKX44470.1 - 0.0077 16.3 2.0 1.7 8.7 0.1 4.7 6 0 0 6 6 5 1 Domain of Unknown Function (DUF3856) RPN7 PF10602.9 EKX44470.1 - 0.34 10.6 6.2 1.8 8.2 0.1 4.2 3 1 1 5 5 5 0 26S proteasome subunit RPN7 SHNi-TPR PF10516.9 EKX44470.1 - 1.2 8.6 3.1 53 3.4 0.1 4.2 4 0 0 4 4 4 0 SHNi-TPR ANAPC3 PF12895.7 EKX44470.1 - 1.8 8.9 9.1 5.3 7.3 0.2 4.1 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TIG PF01833.24 EKX44471.1 - 1.9e-15 56.7 0.0 1.1e-08 35.1 0.0 2.6 2 0 0 2 2 2 2 IPT/TIG domain TPR_2 PF07719.17 EKX44471.1 - 0.0016 18.4 0.3 10 6.5 0.0 5.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX44471.1 - 0.014 15.9 0.4 0.28 11.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EKX44471.1 - 0.028 14.5 1.4 0.2 11.9 1.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EKX44471.1 - 0.032 14.6 0.0 0.46 11.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX44471.1 - 0.032 15.0 6.4 24 6.1 0.1 5.2 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX44471.1 - 0.036 14.4 4.2 3.7 7.9 0.3 4.1 1 1 3 4 4 4 0 Tetratricopeptide repeat Deltaretro_Tax PF05599.11 EKX44471.1 - 0.45 11.1 2.3 7 7.2 0.2 2.5 2 0 0 2 2 2 0 Deltaretrovirus Tax protein TPR_4 PF07721.14 EKX44471.1 - 1.9 9.3 5.4 5.8 7.8 3.8 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 EKX44472.1 - 1e-69 234.9 0.0 1.3e-69 234.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX44472.1 - 9.6e-29 100.4 0.0 1.2e-28 100.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX44472.1 - 1.8e-07 30.8 0.0 2.5e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EKX44472.1 - 0.00035 19.5 0.0 0.00038 19.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EKX44472.1 - 0.0062 15.9 0.1 0.0084 15.5 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EKX44472.1 - 0.022 14.3 1.5 0.054 13.1 0.3 1.8 1 1 1 2 2 2 0 RIO1 family APH PF01636.23 EKX44472.1 - 0.033 14.1 0.1 0.2 11.6 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 EKX44472.1 - 0.071 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 SAM_1 PF00536.30 EKX44473.1 - 2.5e-13 50.2 0.2 9.9e-13 48.3 0.1 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EKX44473.1 - 1.2e-10 41.3 0.2 3.3e-10 39.9 0.2 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Aida_C2 PF14186.6 EKX44473.1 - 0.00045 19.9 0.0 0.0019 17.9 0.0 1.9 1 1 0 1 1 1 1 Cytoskeletal adhesion IGR PF09597.10 EKX44473.1 - 0.00045 20.3 0.3 0.0009 19.3 0.3 1.4 1 0 0 1 1 1 1 IGR protein motif PH PF00169.29 EKX44473.1 - 0.016 15.7 0.0 0.049 14.1 0.0 1.9 1 0 0 1 1 1 0 PH domain SAM_3 PF18016.1 EKX44473.1 - 0.031 14.1 0.4 0.12 12.2 0.1 2.0 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) PIG-F PF06699.11 EKX44476.1 - 7.1e-39 133.8 6.5 1.1e-38 133.2 6.5 1.2 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F ThiF PF00899.21 EKX44476.1 - 1.7e-25 89.8 0.0 2.9e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 ThiF family YqzM PF14141.6 EKX44476.1 - 1.4 9.0 4.3 4 7.6 4.3 1.8 1 0 0 1 1 1 0 YqzM-like protein DnaA_N PF11638.8 EKX44478.1 - 0.21 11.3 1.1 0.37 10.6 0.1 1.9 2 0 0 2 2 2 0 DnaA N-terminal domain Rota_NSP4 PF01452.16 EKX44478.1 - 1.1 8.9 4.9 2.3 7.9 4.9 1.5 1 0 0 1 1 1 0 Rotavirus non structural protein CwsA PF10814.8 EKX44478.1 - 1.2 9.4 5.5 0.8 9.9 1.2 2.4 3 0 0 3 3 3 0 Cell wall synthesis protein CwsA Mitofilin PF09731.9 EKX44478.1 - 1.3 7.8 17.5 1.7 7.4 17.5 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Snapin_Pallidin PF14712.6 EKX44478.1 - 2.1 8.8 12.1 0.33 11.4 1.7 2.8 2 1 1 3 3 3 0 Snapin/Pallidin PHA_gran_rgn PF09650.10 EKX44478.1 - 9.6 6.6 7.4 13 6.1 0.7 3.1 3 0 0 3 3 3 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) RWP-RK PF02042.15 EKX44479.1 - 3.2e-11 43.0 0.1 5.2e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain SAPS PF04499.15 EKX44479.1 - 0.24 10.1 4.0 0.27 10.0 4.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 EKX44479.1 - 8 4.4 7.9 8.9 4.3 7.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ephrin_rec_like PF07699.13 EKX44481.1 - 4.9e-21 74.2 30.1 2e-07 30.7 2.9 4.4 1 1 3 4 4 4 4 Putative ephrin-receptor like NCD3G PF07562.14 EKX44481.1 - 1.4e-06 28.2 25.3 0.00025 21.0 3.4 4.6 1 1 3 5 5 5 4 Nine Cysteines Domain of family 3 GPCR VSP PF03302.13 EKX44481.1 - 0.00054 18.9 22.0 0.0011 17.9 20.7 1.7 1 1 0 1 1 1 1 Giardia variant-specific surface protein TNFR_c6 PF00020.18 EKX44481.1 - 0.0072 16.7 24.6 0.28 11.6 1.8 5.6 1 1 3 4 4 4 3 TNFR/NGFR cysteine-rich region DUF2318 PF10080.9 EKX44481.1 - 0.39 10.9 17.0 2.3 8.4 0.3 3.2 1 1 2 3 3 3 0 Predicted membrane protein (DUF2318) cEGF PF12662.7 EKX44481.1 - 0.67 9.9 0.1 0.67 9.9 0.1 5.0 4 2 0 4 4 4 0 Complement Clr-like EGF-like DUF4215 PF13948.6 EKX44481.1 - 6.3 7.3 16.9 0.94 10.0 0.6 3.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4215) Hist_deacetyl PF00850.19 EKX44482.1 - 3.1e-44 151.7 0.1 7.2e-24 84.8 0.3 2.0 1 1 1 2 2 2 2 Histone deacetylase domain DUF1647 PF07801.11 EKX44483.1 - 5.5e-10 39.1 0.1 1e-09 38.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1647) DUF2150 PF09920.9 EKX44483.1 - 0.096 12.7 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) TPR_2 PF07719.17 EKX44483.1 - 0.42 10.8 2.2 2.6 8.4 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.31 EKX44484.1 - 5e-18 65.0 0.9 5.4e-18 64.9 0.9 1.0 1 0 0 1 1 1 1 DnaJ domain Sugar_tr PF00083.24 EKX44485.1 - 1.2e-69 235.4 15.6 1.7e-40 139.3 0.9 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EKX44485.1 - 1.1e-18 67.4 26.6 1.1e-18 67.4 26.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_3 PF16080.5 EKX44485.1 - 0.37 10.6 2.9 0.6 9.9 0.0 2.8 3 0 0 3 3 3 0 Bacteriophage holin family HP1 ThiF PF00899.21 EKX44486.1 - 2.9e-28 98.9 0.0 4.7e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.6 EKX44486.1 - 0.0053 17.2 0.0 0.013 15.9 0.0 1.8 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 EKX44486.1 - 0.0073 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 EKX44486.1 - 0.0084 15.4 0.1 0.013 14.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain ELFV_dehydrog PF00208.21 EKX44486.1 - 0.028 14.2 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Sacchrp_dh_NADP PF03435.18 EKX44486.1 - 0.031 14.5 0.1 0.12 12.6 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 EKX44486.1 - 0.14 11.8 0.0 0.36 10.5 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DAO PF01266.24 EKX44486.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Med27 PF11571.8 EKX44487.1 - 6.6e-12 45.6 0.3 1.4e-11 44.6 0.3 1.5 1 0 0 1 1 1 1 Mediator complex subunit 27 HlyD_D23 PF16576.5 EKX44487.1 - 0.0006 19.1 0.8 0.0013 18.0 0.2 1.8 2 0 0 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 EKX44487.1 - 0.0049 16.7 0.9 0.063 13.1 0.3 2.5 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 EKX44487.1 - 0.039 14.7 0.8 0.082 13.6 0.1 1.9 2 0 0 2 2 2 0 HlyD family secretion protein Biotin_lipoyl PF00364.22 EKX44487.1 - 0.087 12.7 1.6 0.23 11.3 1.6 1.7 1 1 0 1 1 1 0 Biotin-requiring enzyme PhyH PF05721.13 EKX44488.1 - 8.6e-13 49.0 0.0 1.5e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Citrate_synt PF00285.21 EKX44490.1 - 2.1e-97 326.4 0.0 2.6e-97 326.2 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain SelK_SelG PF10961.8 EKX44494.1 - 0.11 13.2 1.1 0.71 10.5 0.3 2.4 2 1 0 2 2 2 0 Selenoprotein SelK_SelG PWWP PF00855.17 EKX44494.1 - 0.68 10.4 9.0 0.053 13.9 3.5 2.0 2 1 0 2 2 2 0 PWWP domain zf-C2H2_3rep PF18868.1 EKX44494.1 - 0.88 10.2 6.2 0.35 11.6 1.7 2.4 1 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats Muted PF14942.6 EKX44495.1 - 2.8e-09 37.5 14.5 2.8e-09 37.5 14.5 1.4 2 0 0 2 2 2 1 Organelle biogenesis, Muted-like protein DUF745 PF05335.13 EKX44495.1 - 0.009 15.8 16.6 0.02 14.6 16.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF745) Exonuc_VII_L PF02601.15 EKX44495.1 - 0.038 13.6 2.4 0.043 13.4 2.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit TCO89 PF10452.9 EKX44495.1 - 0.21 10.6 5.9 0.26 10.2 5.9 1.1 1 0 0 1 1 1 0 TORC1 subunit TCO89 BLOC1_2 PF10046.9 EKX44495.1 - 0.29 11.5 7.8 0.059 13.7 2.7 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 EKX44495.1 - 0.73 10.1 3.2 2.6 8.4 0.1 2.5 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 EKX44495.1 - 0.86 10.1 16.4 2 8.9 16.4 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region KapB PF08810.10 EKX44495.1 - 1.2 9.3 5.9 0.4 10.9 1.5 2.2 1 1 2 3 3 3 0 Kinase associated protein B DUF3584 PF12128.8 EKX44495.1 - 1.9 5.9 15.6 2.4 5.5 15.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fez1 PF06818.15 EKX44495.1 - 2.3 8.6 15.5 3.5 8.0 15.5 1.2 1 0 0 1 1 1 0 Fez1 Sec2p PF06428.11 EKX44495.1 - 4.9 7.2 13.4 0.16 12.0 1.5 2.3 1 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p DUF4407 PF14362.6 EKX44495.1 - 5.2 6.3 10.7 34 3.6 10.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 EKX44495.1 - 6.9 4.4 9.3 9 4.1 9.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SNARE_assoc PF09335.11 EKX44497.1 - 3.6e-11 43.6 4.0 3.6e-11 43.6 4.0 2.5 2 1 1 3 3 3 1 SNARE associated Golgi protein PDZ_6 PF17820.1 EKX44497.1 - 1.5e-08 34.4 0.1 3e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX44497.1 - 3.4e-06 27.3 0.0 6.5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX44497.1 - 7e-05 23.1 0.0 0.00013 22.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX44497.1 - 0.16 11.9 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain LRR_6 PF13516.6 EKX44498.1 - 6.3e-14 50.8 16.7 8e-05 22.4 0.1 7.1 7 0 0 7 7 7 5 Leucine Rich repeat LRR_1 PF00560.33 EKX44498.1 - 0.0041 17.5 5.7 2.1e+02 3.1 0.0 6.9 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_4 PF12799.7 EKX44498.1 - 0.0074 16.7 6.9 41 4.8 0.1 5.3 4 1 1 5 5 5 1 Leucine Rich repeats (2 copies) V_ATPase_I PF01496.19 EKX44499.1 - 1.5e-275 916.2 0.2 1.3e-188 628.7 0.0 2.0 2 0 0 2 2 2 2 V-type ATPase 116kDa subunit family PI3K_P85_iSH2 PF16454.5 EKX44499.1 - 0.0046 16.6 0.9 0.008 15.8 0.1 1.7 2 0 0 2 2 2 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Mod_r PF07200.13 EKX44499.1 - 0.081 13.0 0.4 0.25 11.4 0.4 1.8 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Spectrin PF00435.21 EKX44499.1 - 0.59 10.7 3.3 0.66 10.5 0.8 2.1 2 0 0 2 2 2 0 Spectrin repeat Actin PF00022.19 EKX44500.1 - 6e-30 104.2 0.0 1.6e-29 102.8 0.0 1.6 1 1 0 1 1 1 1 Actin AAA_9 PF12781.7 EKX44500.1 - 0.096 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 ATP-binding dynein motor region CdhC PF03598.15 EKX44500.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit PdaC PF13739.6 EKX44500.1 - 0.12 13.4 0.1 3.4 8.7 0.1 2.1 2 0 0 2 2 2 0 Deacetylase PdaC MIB_HERC2 PF06701.13 EKX44501.1 - 0.0036 17.5 0.1 0.019 15.2 0.1 2.0 1 1 0 1 1 1 1 Mib_herc2 Yop-YscD_cpl PF16697.5 EKX44501.1 - 0.055 13.8 0.1 0.1 12.9 0.1 1.4 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain DUF2431 PF10354.9 EKX44502.1 - 7.7e-30 104.4 0.0 7.4e-29 101.2 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) DUF4890 PF16231.5 EKX44502.1 - 0.031 14.7 6.6 0.031 14.7 6.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4890) ArAE_2_N PF10337.9 EKX44502.1 - 0.3 10.1 0.9 0.46 9.5 0.9 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Glycoprotein_G PF00802.19 EKX44502.1 - 5.1 6.4 6.2 3.2 7.0 1.1 2.2 2 0 0 2 2 2 0 Pneumovirus attachment glycoprotein G SpoU_methylase PF00588.19 EKX44504.1 - 1.3e-31 109.7 0.0 1.4e-31 109.5 0.0 1.0 1 0 0 1 1 1 1 SpoU rRNA Methylase family RasGAP PF00616.19 EKX44505.1 - 6 6.5 9.1 14 5.3 9.1 1.6 1 1 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase RRM_1 PF00076.22 EKX44506.1 - 6.3e-35 118.8 0.6 3.3e-16 58.9 0.1 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EKX44506.1 - 9.9e-12 44.8 1.1 9.7e-06 25.6 0.1 2.8 2 2 0 2 2 2 2 RNA recognition motif OB_RNB PF08206.11 EKX44506.1 - 0.0043 16.7 0.2 1.4 8.7 0.1 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain Nup35_RRM_2 PF14605.6 EKX44506.1 - 0.038 14.0 0.1 3.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif NID PF07292.13 EKX44506.1 - 0.055 14.1 0.3 6 7.6 0.0 2.3 2 0 0 2 2 2 0 Nmi/IFP 35 domain (NID) PHM7_cyt PF14703.6 EKX44506.1 - 0.11 12.7 0.0 12 6.1 0.0 2.5 1 1 2 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter HABP4_PAI-RBP1 PF04774.15 EKX44507.1 - 0.006 17.4 0.0 0.0075 17.1 0.0 1.2 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family TB PF00683.17 EKX44507.1 - 0.016 14.9 0.4 0.033 14.0 0.4 1.4 1 0 0 1 1 1 0 TB domain HABP4_PAI-RBP1 PF04774.15 EKX44508.1 - 9.1e-05 23.3 2.9 0.00028 21.7 2.9 1.7 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family HBS1_N PF08938.10 EKX44508.1 - 0.24 11.7 3.4 0.48 10.8 3.4 1.5 1 1 0 1 1 1 0 HBS1 N-terminus Phycobilisome PF00502.19 EKX44509.1 - 8.5e-07 29.0 0.0 1.6e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Phycobilisome protein SDA1 PF05285.12 EKX44509.1 - 0.0032 17.0 31.6 0.0032 17.0 31.6 2.2 2 0 0 2 2 2 2 SDA1 BUD22 PF09073.10 EKX44509.1 - 0.03 13.7 45.9 0.13 11.6 25.7 2.4 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.12 EKX44509.1 - 0.21 9.7 50.4 0.062 11.5 30.1 2.3 2 0 0 2 2 2 0 Nop14-like family Anoctamin PF04547.12 EKX44510.1 - 1.5e-24 86.6 2.6 1.1e-23 83.8 0.2 2.0 2 0 0 2 2 2 2 Calcium-activated chloride channel DUF2207 PF09972.9 EKX44510.1 - 0.046 12.5 0.2 0.046 12.5 0.2 2.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) WD40 PF00400.32 EKX44511.1 - 2.6e-56 186.3 26.2 5.1e-09 36.6 0.1 11.4 11 0 0 11 11 11 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX44511.1 - 4.1e-21 75.1 0.1 0.0036 17.5 0.0 7.7 4 2 3 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EKX44511.1 - 3.7e-06 26.7 0.0 0.00047 19.8 0.0 2.7 3 0 0 3 3 3 1 PQQ-like domain Ge1_WD40 PF16529.5 EKX44511.1 - 6.9e-05 22.0 3.2 2.4 7.1 0.0 6.1 2 1 3 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EKX44511.1 - 0.00075 18.3 6.1 2 7.0 0.3 5.1 4 2 1 6 6 6 3 Nucleoporin Nup120/160 WD40_like PF17005.5 EKX44511.1 - 0.0015 17.9 0.0 0.062 12.6 0.0 2.9 2 2 0 3 3 3 1 WD40-like domain RAB3GAP2_N PF14655.6 EKX44511.1 - 0.0053 16.1 0.0 0.73 9.0 0.0 2.7 3 0 0 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ PF01011.21 EKX44511.1 - 0.15 12.0 1.6 20 5.3 0.2 3.7 4 0 0 4 4 4 0 PQQ enzyme repeat BIR PF00653.21 EKX44512.1 - 1.6e-13 51.1 0.3 4.9e-13 49.5 0.3 1.9 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain Ribosomal_L17 PF01196.19 EKX44512.1 - 0.14 13.1 1.2 0.54 11.2 1.2 2.0 1 1 0 1 1 1 0 Ribosomal protein L17 DUF1043 PF06295.12 EKX44512.1 - 1.1 9.3 8.1 0.77 9.8 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) TMF_TATA_bd PF12325.8 EKX44512.1 - 4.7 7.5 13.1 0.45 10.7 4.3 2.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF676 PF05057.14 EKX44513.1 - 7e-38 130.3 0.0 1.3e-37 129.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Ribosomal_L7Ae PF01248.26 EKX44513.1 - 1.6e-05 24.5 0.0 3.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Palm_thioest PF02089.15 EKX44513.1 - 0.0042 17.0 0.0 0.0099 15.7 0.0 1.6 1 0 0 1 1 1 1 Palmitoyl protein thioesterase LemA PF04011.12 EKX44513.1 - 0.033 14.0 0.1 0.068 13.0 0.1 1.4 1 0 0 1 1 1 0 LemA family Nup188_C PF18378.1 EKX44513.1 - 0.13 11.1 0.1 0.22 10.3 0.1 1.3 1 0 0 1 1 1 0 Nuclear pore protein NUP188 C-terminal domain She9_MDM33 PF05546.11 EKX44513.1 - 0.2 11.4 2.3 0.27 11.0 0.0 2.1 2 0 0 2 2 2 0 She9 / Mdm33 family GD_AH_C PF04295.13 EKX44514.1 - 0.0099 14.7 2.6 0.014 14.2 2.6 1.2 1 0 0 1 1 1 1 D-galactarate dehydratase / Altronate hydrolase, C terminus DUF4226 PF10774.9 EKX44514.1 - 0.048 14.0 8.1 0.52 10.6 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) Bmp PF02608.14 EKX44514.1 - 0.42 9.5 3.3 1 8.3 2.3 1.9 1 1 1 2 2 2 0 ABC transporter substrate-binding protein PnrA-like U1snRNP70_N PF12220.8 EKX44514.1 - 0.63 10.7 15.0 1.2 9.8 3.0 2.8 2 1 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal TMF_TATA_bd PF12325.8 EKX44514.1 - 2.6 8.3 31.3 0.066 13.4 11.3 3.4 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding DM PF00751.18 EKX44515.1 - 1.5 8.8 15.7 2.5 8.1 5.5 2.3 2 0 0 2 2 2 0 DM DNA binding domain PDZ_6 PF17820.1 EKX44516.1 - 2.5e-12 46.4 0.1 5.1e-12 45.4 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX44516.1 - 2.5e-06 27.7 0.1 6e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX44516.1 - 0.0002 21.6 0.1 0.00088 19.6 0.1 2.1 2 0 0 2 2 2 1 PDZ domain THEG PF14912.6 EKX44516.1 - 0.067 13.7 0.8 0.17 12.3 0.8 1.7 1 0 0 1 1 1 0 Testicular haploid expressed repeat NHL PF01436.21 EKX44517.1 - 0.04 14.0 1.1 74 3.7 0.0 4.6 4 1 1 5 5 5 0 NHL repeat Glyco_transf_54 PF04666.13 EKX44518.1 - 1.2e-12 47.3 0.0 2.1e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region ApoL PF05461.11 EKX44518.1 - 0.0041 16.5 4.5 0.0062 15.9 4.5 1.2 1 0 0 1 1 1 1 Apolipoprotein L KIAA1430 PF13879.6 EKX44518.1 - 0.011 16.5 4.1 0.029 15.1 4.1 1.7 1 0 0 1 1 1 0 KIAA1430 homologue UPF0242 PF06785.11 EKX44518.1 - 0.094 12.8 2.0 0.19 11.8 2.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus SKA2 PF16740.5 EKX44519.1 - 0.058 13.2 0.2 0.4 10.5 0.2 2.1 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Hexapep PF00132.24 EKX44520.1 - 6.5e-17 60.5 16.7 3.8e-07 29.6 0.8 4.1 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EKX44520.1 - 7.2e-11 41.7 15.8 5.2e-05 22.9 1.1 3.4 3 0 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase tRNA-synt_1c PF00749.21 EKX44521.1 - 2.9e-71 239.9 0.0 1.6e-68 230.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain tRNA_bind PF01588.20 EKX44521.1 - 1.4e-24 86.0 0.0 3.9e-24 84.6 0.0 1.8 2 0 0 2 2 2 1 Putative tRNA binding domain HAD PF12710.7 EKX44522.1 - 2.1e-09 38.0 1.3 1.2e-08 35.5 1.3 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EKX44522.1 - 7.6e-09 35.9 0.0 3.7e-07 30.4 0.0 2.6 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EKX44522.1 - 6.3e-06 26.6 0.3 0.00013 22.3 0.3 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EKX44522.1 - 3.1e-05 23.9 0.0 6.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Beach PF02138.18 EKX44523.1 - 1.1e-119 398.9 0.0 1.3e-119 398.6 0.0 1.0 1 0 0 1 1 1 1 Beige/BEACH domain Ndr PF03096.14 EKX44523.1 - 0.081 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Ndr family Methyltransf_21 PF05050.12 EKX44524.1 - 2.9e-14 53.5 0.0 4.2e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain DUF4147 PF13660.6 EKX44524.1 - 0.052 13.1 0.0 0.073 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) HEAT_2 PF13646.6 EKX44525.1 - 6.6e-25 87.3 18.6 3.8e-10 40.0 0.6 6.2 5 1 1 6 6 6 4 HEAT repeats RWP-RK PF02042.15 EKX44525.1 - 6.3e-15 54.9 0.2 1.7e-14 53.5 0.2 1.8 1 0 0 1 1 1 1 RWP-RK domain HEAT PF02985.22 EKX44525.1 - 1.3e-13 49.9 22.0 0.059 13.6 0.0 9.9 11 0 0 11 11 10 4 HEAT repeat Cnd1 PF12717.7 EKX44525.1 - 4.3e-09 36.6 6.7 0.0035 17.4 0.2 5.2 2 2 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EKX44525.1 - 2.4e-08 34.3 19.9 0.0021 18.5 0.3 7.1 7 1 0 7 7 6 2 HEAT-like repeat Adaptin_N PF01602.20 EKX44525.1 - 7.1e-07 28.2 4.0 0.016 13.8 0.4 3.1 1 1 0 2 2 2 2 Adaptin N terminal region RTP1_C1 PF10363.9 EKX44525.1 - 1.5e-06 28.3 0.8 0.19 11.9 0.0 4.1 3 1 1 4 4 4 3 Required for nuclear transport of RNA pol II C-terminus 1 Cohesin_HEAT PF12765.7 EKX44525.1 - 1.8e-06 28.1 5.7 0.11 12.9 0.1 6.0 6 0 0 6 6 6 1 HEAT repeat associated with sister chromatid cohesion Vac14_Fab1_bd PF12755.7 EKX44525.1 - 7.7e-05 23.2 0.0 11 6.6 0.0 4.5 2 2 2 4 4 4 1 Vacuolar 14 Fab1-binding region Arm PF00514.23 EKX44525.1 - 0.00087 19.2 8.7 3.2 7.9 0.0 5.9 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat RICTOR_M PF14666.6 EKX44525.1 - 0.0018 18.0 2.9 5.2 6.9 0.0 4.7 4 1 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 EKX44525.1 - 0.0024 18.2 5.6 1.2 9.5 0.1 4.8 4 1 1 5 5 5 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT_PBS PF03130.16 EKX44525.1 - 0.0038 17.8 6.0 0.18 12.6 0.0 4.9 5 0 0 5 5 4 1 PBS lyase HEAT-like repeat API5 PF05918.11 EKX44525.1 - 0.0083 15.0 1.2 0.42 9.4 0.1 3.1 4 0 0 4 4 4 1 Apoptosis inhibitory protein 5 (API5) RSRP PF17069.5 EKX44525.1 - 0.03 13.9 0.2 0.053 13.1 0.2 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 SMC_N PF02463.19 EKX44526.1 - 7.6e-09 35.3 11.7 1.4e-07 31.1 11.6 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EKX44526.1 - 8.5e-07 29.1 0.0 2.4e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Metallophos PF00149.28 EKX44526.1 - 1.1e-05 26.1 0.0 2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EKX44526.1 - 0.00015 22.0 0.0 0.00052 20.3 0.0 2.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ABC_tran PF00005.27 EKX44526.1 - 0.075 13.6 0.1 0.075 13.6 0.1 4.4 2 2 0 2 2 2 0 ABC transporter HNH PF01844.23 EKX44526.1 - 0.76 10.0 3.6 5.8 7.2 1.5 2.7 2 0 0 2 2 2 0 HNH endonuclease AAA_23 PF13476.6 EKX44526.1 - 6.8 7.1 53.1 16 5.9 26.5 4.5 2 1 1 3 3 3 0 AAA domain Toprim_3 PF13362.6 EKX44527.1 - 0.082 13.3 0.0 0.09 13.2 0.0 1.1 1 0 0 1 1 1 0 Toprim domain PDZ_6 PF17820.1 EKX44529.1 - 1.1e-06 28.4 0.0 1.7e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX44529.1 - 4.2e-06 27.0 0.0 6.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX44529.1 - 4.7e-05 23.6 0.0 8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX44529.1 - 0.055 13.4 0.0 0.095 12.7 0.0 1.3 1 0 0 1 1 1 0 Tricorn protease PDZ domain GRASP55_65 PF04495.14 EKX44529.1 - 0.1 12.9 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain TPH PF13868.6 EKX44530.1 - 2.2e-18 65.9 119.7 2.2e-18 65.9 119.7 2.1 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain DnaJ PF00226.31 EKX44531.1 - 2.8e-14 53.0 0.2 3.1e-14 52.8 0.2 1.0 1 0 0 1 1 1 1 DnaJ domain zf-C3HC4_2 PF13923.6 EKX44532.1 - 2.3e-10 40.2 14.6 5.9e-10 38.8 14.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX44532.1 - 9.1e-09 35.0 15.5 2.1e-08 33.9 15.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EKX44532.1 - 1.4e-08 34.7 15.8 3.9e-08 33.3 15.8 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EKX44532.1 - 2.2e-07 30.6 11.1 5.4e-07 29.4 11.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX44532.1 - 1.2e-06 28.7 14.7 1.2e-06 28.7 14.7 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EKX44532.1 - 4.5e-06 26.6 14.4 1.2e-05 25.2 14.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_10 PF16685.5 EKX44532.1 - 0.0009 19.3 4.5 0.003 17.7 4.5 2.0 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_5 PF14634.6 EKX44532.1 - 0.0021 18.0 14.7 0.01 15.7 14.8 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.8 EKX44532.1 - 0.0029 17.4 10.1 0.007 16.2 10.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 EKX44532.1 - 0.011 15.6 4.3 0.011 15.6 4.3 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein BRCT_3 PF18428.1 EKX44532.1 - 0.05 13.7 0.0 1.3 9.1 0.0 2.4 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain U-box PF04564.15 EKX44532.1 - 0.13 12.5 0.1 0.45 10.7 0.1 1.9 1 1 1 2 2 2 0 U-box domain Prok-RING_4 PF14447.6 EKX44532.1 - 0.18 11.7 15.9 1.5 8.7 16.3 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EKX44532.1 - 1.1 9.2 15.0 6.7 6.6 15.2 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EKX44532.1 - 1.1 9.6 14.4 7.9 6.8 14.4 2.4 1 1 0 1 1 1 0 RING-H2 zinc finger domain TIG PF01833.24 EKX44533.1 - 9.8e-28 96.1 13.0 1.8e-08 34.3 0.0 5.8 5 1 1 6 6 6 5 IPT/TIG domain TIG_plexin PF17960.1 EKX44533.1 - 1.6e-05 24.8 1.2 0.36 10.9 0.1 4.4 4 0 0 4 4 4 2 TIG domain TIG PF01833.24 EKX44534.1 - 3.5e-50 168.0 28.4 3.5e-08 33.4 0.0 9.5 10 0 0 10 10 10 9 IPT/TIG domain TIG_plexin PF17960.1 EKX44534.1 - 6.2e-08 32.5 2.2 0.03 14.3 0.0 5.0 5 0 0 5 5 5 4 TIG domain TIG PF01833.24 EKX44535.1 - 2.6e-27 94.7 1.3 2.3e-05 24.4 0.0 4.1 4 0 0 4 4 4 4 IPT/TIG domain TIG_plexin PF17960.1 EKX44535.1 - 1.9e-05 24.6 1.2 0.75 9.8 0.1 3.8 4 0 0 4 4 4 3 TIG domain TIG PF01833.24 EKX44536.1 - 1.8e-17 63.2 4.6 1.8e-05 24.7 0.1 4.0 4 0 0 4 4 4 3 IPT/TIG domain TIG_plexin PF17960.1 EKX44536.1 - 6.4e-09 35.7 0.2 0.00078 19.4 0.0 3.8 4 0 0 4 4 4 3 TIG domain Filamin PF00630.19 EKX44537.1 - 3.5e-22 79.2 0.0 4.8e-07 30.5 0.0 3.2 2 1 1 3 3 3 3 Filamin/ABP280 repeat Invasin_D3 PF09134.10 EKX44537.1 - 0.00044 20.5 0.0 1.6 9.0 0.0 3.3 2 1 0 2 2 2 2 Invasin, domain 3 Filamin PF00630.19 EKX44538.1 - 1.6e-22 80.3 0.0 1.1e-10 42.2 0.0 2.1 2 0 0 2 2 2 2 Filamin/ABP280 repeat Invasin_D3 PF09134.10 EKX44538.1 - 2.3e-06 27.8 0.0 0.0098 16.2 0.0 2.2 2 0 0 2 2 2 2 Invasin, domain 3 Neurexophilin PF06312.12 EKX44538.1 - 0.0017 17.9 0.4 1.2 8.5 0.1 2.1 2 0 0 2 2 2 2 Neurexophilin YtkA PF13115.6 EKX44538.1 - 0.041 14.5 0.0 14 6.4 0.0 2.2 2 0 0 2 2 2 0 YtkA-like CPBP PF02517.16 EKX44539.1 - 5.5e-16 58.7 2.3 5.5e-16 58.7 2.3 2.5 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease TnpW PF14202.6 EKX44539.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Transposon-encoded protein TnpW HCMV_UL124 PF17609.2 EKX44539.1 - 0.17 12.1 0.4 0.4 10.9 0.1 1.7 1 1 0 1 1 1 0 Family of unknown function PKD_channel PF08016.12 EKX44540.1 - 7.8e-38 130.3 13.4 1.2e-37 129.6 13.4 1.3 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 EKX44540.1 - 5.3e-09 35.7 27.0 5.9e-09 35.5 21.5 2.2 1 1 1 2 2 2 2 Ion transport protein TTL PF03133.15 EKX44541.1 - 6.7e-63 212.6 0.0 8.7e-63 212.2 0.0 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family NRN1 PF15056.6 EKX44542.1 - 0.97 9.6 5.3 1.2 9.3 0.1 3.6 3 0 0 3 3 3 0 Neuritin protein family Kinesin PF00225.23 EKX44543.1 - 3.5e-74 249.7 0.3 4.1e-74 249.5 0.3 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX44543.1 - 6.1e-15 55.5 0.0 1.3e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Ppx-GppA PF02541.16 EKX44543.1 - 0.02 14.3 0.1 0.032 13.7 0.1 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Glyco_transf_41 PF13844.6 EKX44545.1 - 3.6e-53 180.7 0.3 6.4e-23 80.9 0.0 3.1 2 1 1 3 3 3 3 Glycosyl transferase family 41 TPR_8 PF13181.6 EKX44545.1 - 3.7e-19 67.3 0.8 0.00023 21.2 0.1 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 EKX44545.1 - 8.1e-19 66.6 1.6 3.4e-06 26.6 0.2 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX44545.1 - 2.7e-18 64.5 3.2 1.1e-06 28.2 0.3 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX44545.1 - 2.4e-13 49.5 4.0 0.0016 18.1 0.0 4.5 1 1 3 4 4 4 3 TPR repeat TPR_14 PF13428.6 EKX44545.1 - 1.7e-10 40.8 11.5 0.17 12.7 0.0 6.2 3 1 3 6 6 5 5 Tetratricopeptide repeat TPR_17 PF13431.6 EKX44545.1 - 8.8e-10 38.3 4.2 0.034 14.5 0.1 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 EKX44545.1 - 4.6e-09 35.9 3.3 4.6e-09 35.9 3.3 2.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX44545.1 - 4.3e-07 30.4 8.8 0.0031 18.0 0.3 3.8 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX44545.1 - 9.3e-07 29.1 4.2 0.0003 21.0 0.1 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX44545.1 - 3e-06 27.8 10.4 1.9e-05 25.2 0.3 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX44545.1 - 3e-05 24.2 0.1 0.00053 20.2 0.0 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 HEAT_2 PF13646.6 EKX44545.1 - 0.0016 18.8 1.1 0.021 15.2 0.1 2.8 2 0 0 2 2 2 1 HEAT repeats TPR_20 PF14561.6 EKX44545.1 - 0.0026 18.0 1.5 0.092 13.1 0.1 3.3 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX44545.1 - 0.014 15.5 0.6 0.18 12.0 0.1 2.6 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX44545.1 - 0.018 14.9 0.2 0.018 14.9 0.2 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat NARP1 PF12569.8 EKX44545.1 - 0.073 12.0 0.1 3.4 6.5 0.0 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 EKX44545.1 - 0.21 12.3 4.2 10 7.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EKX44545.1 - 0.81 9.9 4.4 12 6.2 0.1 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat Mito_carr PF00153.27 EKX44546.1 - 6e-64 212.0 3.3 3.4e-21 75.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EKX44546.1 - 0.13 11.4 0.7 2.3 7.3 0.1 2.4 2 1 0 2 2 2 0 Gammaproteobacterial serine protease GTP_EFTU PF00009.27 EKX44547.1 - 4.7e-55 186.2 0.3 7.3e-55 185.5 0.3 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EKX44547.1 - 7.4e-21 74.0 0.0 1.6e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EKX44547.1 - 2.3e-09 37.5 3.2 5.1e-09 36.4 3.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EKX44547.1 - 1.3e-06 28.5 0.2 9e-06 25.8 0.1 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Septin PF00735.18 EKX44547.1 - 0.0027 17.0 0.1 0.0053 16.1 0.1 1.4 1 0 0 1 1 1 1 Septin AIG1 PF04548.16 EKX44547.1 - 0.0098 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 EKX44547.1 - 0.021 15.0 0.0 0.041 14.1 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EKX44547.1 - 0.031 14.2 0.1 1.5 8.7 0.0 2.5 2 1 0 2 2 2 0 RsgA GTPase SRPRB PF09439.10 EKX44547.1 - 0.071 12.5 0.0 0.68 9.3 0.1 2.3 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF5624 PF18538.1 EKX44548.1 - 0.02 15.0 0.3 0.11 12.6 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF5624) DUF724 PF05266.14 EKX44548.1 - 0.06 13.2 21.4 0.54 10.1 5.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Spc7 PF08317.11 EKX44548.1 - 0.33 9.8 28.6 0.16 10.8 25.5 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein CC2-LZ PF16516.5 EKX44548.1 - 1.3 9.4 23.6 0.24 11.8 4.1 3.2 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Nbl1_Borealin_N PF10444.9 EKX44548.1 - 1.6 8.4 8.9 2.3 7.9 0.4 3.6 3 1 0 3 3 3 0 Nbl1 / Borealin N terminal PDZ_3 PF17815.1 EKX44549.1 - 1.8e-29 102.5 0.0 4.6e-29 101.1 0.0 1.7 2 0 0 2 2 2 1 PDZ domain Trypsin_2 PF13365.6 EKX44549.1 - 3.2e-22 80.0 1.2 8.1e-22 78.7 1.2 1.6 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 EKX44549.1 - 6.2e-17 62.1 0.0 9.4e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 EKX44549.1 - 0.0003 21.0 0.0 0.00058 20.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX44549.1 - 0.01 16.1 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 PDZ domain WW PF00397.26 EKX44550.1 - 1.7e-06 28.0 0.1 2.8e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 WW domain F5_F8_type_C PF00754.25 EKX44551.1 - 1.3e-05 25.3 0.0 2e-05 24.7 0.0 1.3 1 1 0 1 1 1 1 F5/8 type C domain LRR_6 PF13516.6 EKX44552.1 - 1.9e-16 58.6 23.3 0.026 14.5 0.2 9.6 10 0 0 10 10 10 5 Leucine Rich repeat LRR_4 PF12799.7 EKX44552.1 - 3.4e-08 33.7 15.8 0.044 14.2 0.6 6.8 5 2 2 8 8 8 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX44552.1 - 4.2e-05 23.5 14.8 19 6.3 0.0 8.3 8 1 0 8 8 8 1 Leucine Rich Repeat LRR_8 PF13855.6 EKX44552.1 - 0.006 16.3 13.4 0.094 12.5 0.5 5.4 5 2 1 6 6 6 2 Leucine rich repeat Preseq_ALAS PF09029.10 EKX44552.1 - 0.022 15.3 0.6 8.3 6.9 0.1 3.0 3 0 0 3 3 3 0 5-aminolevulinate synthase presequence AA_kinase PF00696.28 EKX44553.1 - 4e-30 105.2 0.1 9.7e-30 103.9 0.1 1.7 1 1 0 1 1 1 1 Amino acid kinase family Aldedh PF00171.22 EKX44553.1 - 7.4e-12 44.5 0.6 2.8e-06 26.1 0.0 3.1 3 0 0 3 3 3 3 Aldehyde dehydrogenase family zf-CHY PF05495.12 EKX44554.1 - 5.5e-09 36.4 7.0 6.3e-09 36.2 7.0 1.0 1 0 0 1 1 1 1 CHY zinc finger Lar_restr_allev PF14354.6 EKX44554.1 - 0.0093 16.3 2.0 0.0093 16.3 2.0 1.5 1 1 0 1 1 1 1 Restriction alleviation protein Lar WD40 PF00400.32 EKX44555.1 - 2.7e-58 192.6 13.2 5.4e-11 42.9 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX44555.1 - 4.8e-26 90.9 0.0 1.6e-06 28.3 0.0 4.3 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX44555.1 - 3.6e-10 39.3 0.0 0.12 11.3 0.0 4.3 2 1 1 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EKX44555.1 - 3e-05 24.0 0.0 0.002 18.0 0.0 2.3 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EKX44555.1 - 0.00027 19.7 0.0 0.012 14.3 0.0 2.8 3 0 0 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EKX44555.1 - 0.0012 17.6 0.0 2.1 7.0 0.0 3.3 2 1 0 3 3 3 2 Nup133 N terminal like Nbas_N PF15492.6 EKX44555.1 - 0.0042 16.5 0.6 0.11 11.8 0.0 3.0 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal DUF4776 PF16003.5 EKX44556.1 - 1.5 7.7 10.3 2.2 7.2 10.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) RIBIOP_C PF04950.12 EKX44557.1 - 8.8e-43 146.8 0.0 9.9e-21 74.4 0.0 3.1 1 1 1 2 2 2 2 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EKX44557.1 - 3.4e-13 49.5 0.0 1e-12 47.9 0.0 1.8 2 0 0 2 2 2 1 AARP2CN (NUC121) domain TPR_1 PF00515.28 EKX44558.1 - 1.6e-09 37.2 1.1 0.038 13.8 0.1 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX44558.1 - 1.7e-09 37.0 6.0 0.056 13.6 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX44558.1 - 3.1e-07 30.6 2.4 0.045 14.6 0.0 4.2 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX44558.1 - 3.7e-07 30.5 1.1 0.00051 20.5 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX44558.1 - 5.7e-07 29.3 0.6 0.74 10.2 0.1 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX44558.1 - 4.4e-06 26.8 5.4 0.035 14.2 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX44558.1 - 0.00011 21.9 1.5 0.011 15.7 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX44558.1 - 0.00022 21.5 4.8 0.0073 16.6 0.0 3.8 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX44558.1 - 0.00027 20.6 0.0 0.57 9.9 0.0 3.6 2 1 1 3 3 3 1 TPR repeat ANAPC3 PF12895.7 EKX44558.1 - 0.0013 18.9 0.3 0.17 12.1 0.2 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EKX44558.1 - 0.0021 18.3 0.0 0.71 10.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX44558.1 - 0.0037 17.9 0.5 3.9 8.2 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX44558.1 - 0.023 14.6 1.1 31 4.6 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2967 PF11179.8 EKX44558.1 - 0.19 9.8 1.2 0.24 9.4 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) DUF4404 PF14357.6 EKX44558.1 - 0.23 12.1 1.8 0.96 10.1 1.8 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) DUF3482 PF11981.8 EKX44558.1 - 0.4 10.0 9.3 0.088 12.2 5.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) Keratin_2_head PF16208.5 EKX44558.1 - 0.93 9.6 17.7 1.5 8.9 17.7 1.2 1 0 0 1 1 1 0 Keratin type II head KRTAP PF11759.8 EKX44558.1 - 4.8 7.8 14.7 9.1 6.9 14.7 1.3 1 0 0 1 1 1 0 Keratin-associated matrix CBM_20 PF00686.19 EKX44559.1 - 3.3e-13 49.3 0.0 5.6e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Starch binding domain TarH PF02203.15 EKX44559.1 - 0.01 15.8 1.1 0.019 14.9 1.0 1.5 1 1 0 1 1 1 0 Tar ligand binding domain homologue NUDIX PF00293.28 EKX44560.1 - 1.7 8.7 5.8 0.37 10.8 0.1 2.4 1 1 1 2 2 2 0 NUDIX domain DEAD PF00270.29 EKX44561.1 - 1.2e-38 132.6 0.4 3.2e-38 131.2 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX44561.1 - 8.6e-25 87.2 2.1 1.6e-24 86.4 0.1 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX44561.1 - 6.4e-06 26.3 1.3 2.3e-05 24.5 0.0 2.5 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EKX44561.1 - 0.0078 16.5 1.1 0.098 12.9 1.1 2.8 1 1 0 1 1 1 1 AAA domain DUF4672 PF15716.5 EKX44561.1 - 0.65 9.6 11.5 0.025 14.2 4.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4672) RCC1 PF00415.18 EKX44562.1 - 2.8e-48 162.3 19.5 2.1e-10 41.1 0.2 6.2 6 2 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX44562.1 - 1.6e-39 132.9 35.1 1.7e-08 34.0 0.8 6.3 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 EKX44562.1 - 0.017 14.9 2.7 3.4 7.3 0.1 3.4 4 0 0 4 4 4 0 TUP1-like enhancer of split DUF503 PF04456.12 EKX44562.1 - 0.11 12.4 0.0 0.35 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF503) MurB_C PF02873.16 EKX44562.1 - 0.15 12.1 0.0 5.9 7.0 0.0 2.7 3 0 0 3 3 3 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain ANAPC4_WD40 PF12894.7 EKX44563.1 - 8.9e-11 42.0 0.0 0.13 12.5 0.0 6.4 2 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EKX44563.1 - 8.7e-10 39.0 2.9 0.076 13.9 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.11 EKX44563.1 - 0.0095 15.8 0.0 1.7 8.5 0.0 3.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PSII_BNR PF14870.6 EKX44563.1 - 0.038 13.2 0.1 0.056 12.7 0.1 1.2 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 PD40 PF07676.12 EKX44563.1 - 0.096 12.7 0.0 47 4.1 0.0 3.3 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EKX44563.1 - 0.13 10.8 0.0 4.5 5.7 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain IKI3 PF04762.12 EKX44563.1 - 0.23 9.4 0.0 0.72 7.8 0.0 1.7 2 1 0 2 2 2 0 IKI3 family Ribosomal_S16 PF00886.19 EKX44564.1 - 5.5e-26 90.4 0.0 7.1e-26 90.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 EGF_2 PF07974.13 EKX44567.1 - 0.7 10.3 145.5 0.08 13.3 15.7 8.6 8 0 0 8 8 8 0 EGF-like domain PHTB1_N PF14727.6 EKX44568.1 - 3.6e-108 362.6 0.0 5.1e-108 362.1 0.0 1.2 1 0 0 1 1 1 1 PTHB1 N-terminus PHTB1_C PF14728.6 EKX44568.1 - 1.6e-94 317.1 0.0 2.1e-94 316.7 0.0 1.1 1 0 0 1 1 1 1 PTHB1 C-terminus NPCBM_assoc PF10633.9 EKX44568.1 - 0.072 13.3 0.1 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase ABC_membrane PF00664.23 EKX44569.1 - 3.5e-54 184.3 20.9 4.7e-54 183.9 20.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EKX44569.1 - 2.8e-32 112.1 0.0 5.1e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EKX44569.1 - 5.5e-05 22.7 0.4 0.0054 16.2 0.0 2.7 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EKX44569.1 - 0.023 14.5 0.0 0.57 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EKX44569.1 - 0.034 14.4 0.4 0.68 10.2 0.4 2.5 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EKX44569.1 - 0.053 13.3 0.1 0.16 11.7 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EKX44569.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Thymidylate_kin PF02223.17 EKX44569.1 - 0.078 12.6 0.2 12 5.6 0.0 3.1 3 0 0 3 3 3 0 Thymidylate kinase AAA_25 PF13481.6 EKX44569.1 - 0.1 12.2 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EKX44569.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 EKX44569.1 - 0.19 11.0 0.0 0.44 9.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 EKX44569.1 - 0.2 12.0 0.8 1.4 9.3 0.8 2.4 1 1 0 1 1 1 0 AAA ATPase domain Laminin_II PF06009.12 EKX44570.1 - 0.012 15.7 0.1 0.02 14.9 0.1 1.2 1 0 0 1 1 1 0 Laminin Domain II DUF677 PF05055.12 EKX44570.1 - 0.21 10.4 0.0 0.34 9.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Prefoldin PF02996.17 EKX44571.1 - 8.6e-05 22.4 0.0 0.00013 21.8 0.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit DNA_pol_phi PF04931.13 EKX44571.1 - 3.5 5.6 7.5 3.7 5.5 7.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi RuvX PF03652.15 EKX44572.1 - 1.2e-26 93.6 0.0 1.4e-26 93.5 0.0 1.0 1 0 0 1 1 1 1 Holliday junction resolvase Ribonuc_P_40 PF08584.11 EKX44572.1 - 0.19 11.0 0.0 0.22 10.8 0.0 1.1 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit PrmA PF06325.13 EKX44573.1 - 2.6e-34 119.0 0.0 3.4e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EKX44573.1 - 8.9e-10 38.6 0.0 1e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EKX44573.1 - 6.9e-07 29.0 0.0 1.1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EKX44573.1 - 3.5e-06 27.6 0.0 6.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX44573.1 - 1.8e-05 24.6 0.0 2.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EKX44573.1 - 7.6e-05 22.7 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX44573.1 - 0.00074 20.1 0.0 0.0013 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EKX44573.1 - 0.0018 18.0 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_16 PF10294.9 EKX44573.1 - 0.0027 17.4 0.0 0.0035 17.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 EKX44573.1 - 0.0034 18.1 0.0 0.0059 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EKX44573.1 - 0.01 15.6 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 EKX44573.1 - 0.028 14.1 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein DOT1 PF08123.13 EKX44573.1 - 0.048 13.2 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_32 PF13679.6 EKX44573.1 - 0.12 12.3 0.1 0.19 11.7 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase domain PDZ_6 PF17820.1 EKX44574.1 - 4.8e-10 39.1 0.1 7.7e-10 38.5 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX44574.1 - 1.6e-08 34.7 0.2 2.2e-08 34.3 0.2 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX44574.1 - 1.8e-05 24.9 0.3 2.4e-05 24.5 0.3 1.2 1 0 0 1 1 1 1 PDZ domain SH3_15 PF18346.1 EKX44574.1 - 0.14 12.5 0.1 0.37 11.1 0.0 1.8 1 1 0 1 1 1 0 Mind bomb SH3 repeat domain ADIP PF11559.8 EKX44576.1 - 0.017 15.2 10.4 0.033 14.3 10.4 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding SQS_PSY PF00494.19 EKX44576.1 - 0.047 13.2 0.1 0.062 12.8 0.1 1.2 1 0 0 1 1 1 0 Squalene/phytoene synthase DUF1043 PF06295.12 EKX44576.1 - 0.065 13.2 5.6 0.13 12.2 5.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) EspA PF03433.13 EKX44576.1 - 0.22 11.3 3.4 0.17 11.7 1.2 2.1 2 1 0 2 2 2 0 EspA-like secreted protein Copine PF07002.16 EKX44577.1 - 3.4e-70 235.9 0.1 4.7e-70 235.4 0.1 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 EKX44577.1 - 1.4e-19 70.3 1.2 1.5e-10 41.3 0.1 2.7 3 0 0 3 3 3 2 C2 domain WW PF00397.26 EKX44577.1 - 4.5e-11 42.6 0.2 8.5e-11 41.8 0.2 1.5 1 0 0 1 1 1 1 WW domain vWA-TerF-like PF10138.9 EKX44577.1 - 5.5e-07 29.9 0.0 1.1e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus PKD_channel PF08016.12 EKX44578.1 - 5.7e-18 64.8 14.4 1e-17 64.0 14.4 1.4 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 EKX44578.1 - 7.5e-13 48.3 21.5 7.5e-13 48.3 21.5 1.8 2 0 0 2 2 2 1 Ion transport protein DUF2247 PF10004.9 EKX44578.1 - 0.0076 16.0 0.4 0.021 14.6 0.4 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2247) peroxidase PF00141.23 EKX44579.1 - 1.1e-20 74.4 0.0 1.9e-20 73.6 0.0 1.4 1 1 0 1 1 1 1 Peroxidase ART PF01129.18 EKX44580.1 - 0.00013 21.4 0.0 0.00036 19.9 0.0 1.7 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase DUF445 PF04286.12 EKX44580.1 - 0.0056 16.5 3.4 0.016 15.0 3.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF445) Malic_M PF03949.15 EKX44581.1 - 4.8e-93 311.2 0.2 6e-93 310.8 0.2 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EKX44581.1 - 7.7e-71 237.6 0.0 1.1e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain NAD_Gly3P_dh_N PF01210.23 EKX44581.1 - 0.013 15.5 0.1 0.029 14.3 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus VDE PF07137.11 EKX44584.1 - 3.4e-67 226.5 3.2 4.1e-67 226.2 3.2 1.1 1 0 0 1 1 1 1 VDE lipocalin domain Lipocalin PF00061.23 EKX44584.1 - 0.0026 18.0 0.0 0.0045 17.2 0.0 1.5 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Lipocalin_2 PF08212.12 EKX44584.1 - 0.0069 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipocalin-like domain Toxin_12 PF07740.12 EKX44584.1 - 0.91 10.3 8.1 3.8 8.3 8.1 2.1 1 0 0 1 1 1 0 Ion channel inhibitory toxin RWP-RK PF02042.15 EKX44585.1 - 3e-13 49.5 0.0 5.7e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain LPD3 PF18798.1 EKX44586.1 - 0.011 15.9 0.0 9.7 6.5 0.0 2.8 1 1 2 3 3 3 0 Large polyvalent protein-associated domain 3 NDUFA12 PF05071.16 EKX44586.1 - 0.035 14.9 6.0 9.5 7.1 0.2 3.1 1 1 2 3 3 3 0 NADH ubiquinone oxidoreductase subunit NDUFA12 ChW PF07538.11 EKX44586.1 - 6.9 6.7 8.3 6.3 6.8 0.1 3.3 3 0 0 3 3 3 0 Clostridial hydrophobic W PDZ PF00595.24 EKX44587.1 - 0.00069 19.9 0.3 0.0016 18.7 0.1 1.7 2 0 0 2 2 2 1 PDZ domain PKcGMP_CC PF16808.5 EKX44588.1 - 2.8e-06 27.0 8.3 0.001 18.9 0.3 3.5 3 0 0 3 3 3 2 Coiled-coil N-terminus of cGMP-dependent protein kinase SlyX PF04102.12 EKX44588.1 - 8.5e-05 23.1 2.7 8.5e-05 23.1 2.7 3.7 2 2 1 3 3 3 1 SlyX AAA_13 PF13166.6 EKX44588.1 - 8.9e-05 21.3 2.5 0.00033 19.5 2.5 1.7 1 1 0 1 1 1 1 AAA domain Csm1_N PF18504.1 EKX44588.1 - 0.00011 22.5 2.4 0.00011 22.5 2.4 4.0 2 2 2 4 4 4 1 Csm1 N-terminal domain MscS_porin PF12795.7 EKX44588.1 - 0.00028 20.5 5.6 0.00028 20.5 5.6 2.2 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain NPV_P10 PF05531.12 EKX44588.1 - 0.00041 20.8 4.5 0.56 10.7 0.3 2.9 2 1 1 3 3 3 2 Nucleopolyhedrovirus P10 protein DUF724 PF05266.14 EKX44588.1 - 0.00061 19.7 1.5 0.00061 19.7 1.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF724) Fez1 PF06818.15 EKX44588.1 - 0.00071 20.1 10.8 0.039 14.4 2.5 2.2 2 0 0 2 2 2 2 Fez1 Lebercilin PF15619.6 EKX44588.1 - 0.00086 19.0 16.8 0.0013 18.4 4.4 2.2 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease ATG16 PF08614.11 EKX44588.1 - 0.0016 18.7 6.7 0.0016 18.7 6.7 2.1 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 EKX44588.1 - 0.0026 17.8 4.2 0.087 12.9 0.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) KASH_CCD PF14662.6 EKX44588.1 - 0.0029 17.5 12.6 0.039 13.8 2.3 2.2 2 0 0 2 2 2 2 Coiled-coil region of CCDC155 or KASH Sec2p PF06428.11 EKX44588.1 - 0.0036 17.2 20.4 0.048 13.6 1.8 3.9 2 2 2 4 4 4 2 GDP/GTP exchange factor Sec2p DUF4763 PF15960.5 EKX44588.1 - 0.0039 16.5 1.0 0.0039 16.5 1.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4763) Spc7 PF08317.11 EKX44588.1 - 0.0052 15.7 15.1 0.03 13.2 3.8 2.1 2 0 0 2 2 2 2 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 EKX44588.1 - 0.0052 16.9 13.4 0.015 15.5 2.3 2.3 2 0 0 2 2 2 1 Tropomyosin like HemX PF04375.14 EKX44588.1 - 0.01 15.1 8.4 0.039 13.2 0.3 2.1 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Nup54 PF13874.6 EKX44588.1 - 0.014 15.5 3.1 0.014 15.5 3.1 2.4 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 CEP63 PF17045.5 EKX44588.1 - 0.015 15.2 13.4 0.027 14.4 4.1 2.1 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa Cep57_CLD_2 PF14197.6 EKX44588.1 - 0.016 15.2 2.4 0.016 15.2 2.4 4.2 2 2 2 4 4 4 0 Centrosome localisation domain of PPC89 Baculo_PEP_C PF04513.12 EKX44588.1 - 0.017 15.1 7.8 0.35 10.9 1.1 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.9 EKX44588.1 - 0.017 14.2 9.6 0.053 12.6 0.9 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 EKX44588.1 - 0.039 14.0 1.3 0.039 14.0 1.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ABC_tran_CTD PF16326.5 EKX44588.1 - 0.041 14.1 15.3 0.37 11.1 0.7 3.8 2 2 3 5 5 5 0 ABC transporter C-terminal domain TBCC_N PF16752.5 EKX44588.1 - 0.046 14.2 12.4 0.16 12.4 3.3 2.4 2 1 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Dynactin_p22 PF07426.11 EKX44588.1 - 0.069 13.0 6.9 0.57 10.0 0.7 2.4 2 0 0 2 2 2 0 Dynactin subunit p22 DUF16 PF01519.16 EKX44588.1 - 0.098 13.2 0.4 0.098 13.2 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 EKX44588.1 - 0.13 12.5 12.1 0.99 9.6 0.2 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family MPS2 PF17060.5 EKX44588.1 - 0.13 11.5 15.1 1.1 8.4 9.1 2.8 1 1 1 2 2 2 0 Monopolar spindle protein 2 FapA PF03961.13 EKX44588.1 - 0.15 10.6 7.2 0.51 8.9 0.5 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A HOOK PF05622.12 EKX44588.1 - 0.17 10.0 12.9 0.12 10.4 7.8 1.9 1 1 1 2 2 2 0 HOOK protein Yuri_gagarin PF15934.5 EKX44588.1 - 0.18 11.6 8.5 0.15 11.9 1.3 2.2 2 0 0 2 2 2 0 Yuri gagarin GAS PF13851.6 EKX44588.1 - 0.2 11.0 13.1 0.51 9.6 3.7 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding OmpH PF03938.14 EKX44588.1 - 0.21 11.9 13.2 0.62 10.4 1.6 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) CENP-H PF05837.12 EKX44588.1 - 0.24 11.8 17.0 0.54 10.7 4.3 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Uso1_p115_C PF04871.13 EKX44588.1 - 0.27 11.6 19.2 0.21 11.9 3.5 2.6 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Wtap PF17098.5 EKX44588.1 - 0.27 11.1 16.3 0.24 11.3 0.9 3.4 2 2 1 3 3 3 0 WTAP/Mum2p family Seryl_tRNA_N PF02403.22 EKX44588.1 - 0.28 11.4 18.0 0.12 12.6 4.9 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Med9 PF07544.13 EKX44588.1 - 0.29 11.3 15.7 0.53 10.4 1.7 3.9 2 2 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Jnk-SapK_ap_N PF09744.9 EKX44588.1 - 0.32 11.2 15.9 0.32 11.2 4.0 2.4 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 SHE3 PF17078.5 EKX44588.1 - 0.32 10.7 8.5 1.7 8.3 1.4 2.2 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Gp58 PF07902.11 EKX44588.1 - 0.33 9.2 7.3 3.2 5.9 6.9 1.9 1 1 0 1 1 1 0 gp58-like protein MRP-L47 PF06984.13 EKX44588.1 - 0.37 10.9 4.5 0.3 11.2 0.6 2.3 2 0 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF4407 PF14362.6 EKX44588.1 - 0.48 9.7 13.4 14 4.9 13.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 EKX44588.1 - 0.51 10.4 17.1 0.061 13.3 4.9 2.7 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMPIT PF07851.13 EKX44588.1 - 0.61 9.3 8.2 2.8 7.1 1.9 2.1 2 0 0 2 2 2 0 TMPIT-like protein Occludin_ELL PF07303.13 EKX44588.1 - 0.71 10.6 10.5 5.9 7.7 1.2 2.5 2 1 0 2 2 2 0 Occludin homology domain DUF4988 PF16378.5 EKX44588.1 - 0.79 9.4 3.6 1.1 8.9 0.4 2.5 2 2 1 3 3 3 0 Domain of unknown function DUF745 PF05335.13 EKX44588.1 - 1.3 8.7 10.3 0.45 10.2 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) XLF PF09302.11 EKX44588.1 - 1.7 8.8 9.3 1.9 8.7 0.2 3.0 2 1 1 3 3 3 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Exonuc_VII_L PF02601.15 EKX44588.1 - 1.8 8.1 13.2 6.6 6.2 13.2 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit Phage_GPO PF05929.11 EKX44588.1 - 1.8 8.1 6.7 2.6 7.6 0.3 2.3 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase FlaC_arch PF05377.11 EKX44588.1 - 2.3 8.7 10.2 28 5.2 0.6 3.9 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF2570 PF10828.8 EKX44588.1 - 2.7 7.8 11.3 0.45 10.3 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Spc29 PF17082.5 EKX44588.1 - 3 7.6 11.6 2.1 8.1 1.8 3.2 1 1 1 3 3 3 0 Spindle Pole Component 29 ADIP PF11559.8 EKX44588.1 - 3.1 7.9 18.8 2.2 8.3 2.4 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding SKA2 PF16740.5 EKX44588.1 - 3.3 7.5 12.7 0.2 11.4 1.5 3.2 2 2 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF2203 PF09969.9 EKX44588.1 - 3.6 8.3 7.7 14 6.5 1.9 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF743 PF05332.11 EKX44588.1 - 3.7 7.6 6.5 10 6.2 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF743) Bacillus_HBL PF05791.11 EKX44588.1 - 3.9 7.3 9.1 1.2 8.9 0.5 2.2 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DASH_Spc34 PF08657.10 EKX44588.1 - 8 6.2 10.4 0.24 11.1 3.0 2.0 2 1 0 2 2 2 0 DASH complex subunit Spc34 Spc42p PF11544.8 EKX44588.1 - 9.4 6.3 14.1 2.9 7.9 0.1 3.3 3 1 0 3 3 3 0 Spindle pole body component Spc42p DUF4349 PF14257.6 EKX44588.1 - 9.6 5.6 12.9 1.8 8.0 7.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4349) VPS9 PF02204.18 EKX44589.1 - 8.8e-29 99.8 0.1 1.3e-28 99.3 0.1 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EKX44589.1 - 0.028 14.7 0.0 0.078 13.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) NAC PF01849.18 EKX44590.1 - 3.2e-14 52.6 0.1 5.5e-14 51.9 0.0 1.4 2 0 0 2 2 2 1 NAC domain MGAT2 PF05060.14 EKX44591.1 - 1.5e-31 109.7 0.0 7.9e-18 64.6 0.0 2.2 2 0 0 2 2 2 2 N-acetylglucosaminyltransferase II (MGAT2) DUF4214 PF13946.6 EKX44591.1 - 4.8e-07 29.7 0.0 6.5e-05 22.9 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4214) Peptidase_S51 PF03575.17 EKX44591.1 - 0.2 11.3 0.0 0.53 9.9 0.0 1.7 2 0 0 2 2 2 0 Peptidase family S51 Pro_CA PF00484.19 EKX44592.1 - 4e-41 140.9 0.1 5.5e-41 140.5 0.1 1.2 1 0 0 1 1 1 1 Carbonic anhydrase EF-hand_5 PF13202.6 EKX44593.1 - 0.019 14.4 0.1 0.048 13.2 0.1 1.6 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 EKX44593.1 - 0.055 13.0 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 EF hand Haem_bd PF14376.6 EKX44593.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Haem-binding domain EF-hand_7 PF13499.6 EKX44593.1 - 0.15 12.5 0.0 0.44 11.0 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair RWP-RK PF02042.15 EKX44594.1 - 1.3e-13 50.6 0.1 2.2e-13 49.9 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain MttA_Hcf106 PF02416.16 EKX44594.1 - 0.022 14.1 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 mttA/Hcf106 family DUF1853 PF08907.11 EKX44594.1 - 0.044 13.5 0.1 0.063 13.0 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1853) Sigma70_r4_2 PF08281.12 EKX44594.1 - 0.049 13.3 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_8 PF02954.19 EKX44594.1 - 0.14 11.9 0.1 0.34 10.7 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family DUF1641 PF07849.11 EKX44594.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) Homeobox_KN PF05920.11 EKX44595.1 - 2.2e-15 56.3 0.2 5.4e-15 55.0 0.2 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EKX44595.1 - 0.00063 19.5 0.1 0.0019 18.0 0.1 1.8 1 0 0 1 1 1 1 Homeodomain DUF4256 PF14066.6 EKX44595.1 - 0.33 10.6 4.1 0.52 10.0 2.3 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF4256) RWP-RK PF02042.15 EKX44596.1 - 1.2e-13 50.7 0.1 2e-13 50.1 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain MttA_Hcf106 PF02416.16 EKX44596.1 - 0.023 14.0 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 mttA/Hcf106 family Sigma70_r4_2 PF08281.12 EKX44596.1 - 0.044 13.5 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_8 PF02954.19 EKX44596.1 - 0.15 11.9 0.1 0.32 10.8 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family DUF1641 PF07849.11 EKX44596.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) Carboxyl_trans PF01039.22 EKX44597.1 - 5.3e-141 470.6 0.0 7.7e-141 470.1 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain ACC_central PF08326.12 EKX44597.1 - 1.2e-99 334.5 0.8 8e-97 325.2 0.5 2.2 2 0 0 2 2 2 2 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.17 EKX44597.1 - 1.6e-49 168.3 0.0 6.8e-49 166.2 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EKX44597.1 - 7.3e-29 100.5 0.2 2.7e-28 98.7 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EKX44597.1 - 2.1e-19 69.6 0.0 4.7e-19 68.5 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EKX44597.1 - 5.4e-10 39.0 0.0 1.3e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 EKX44597.1 - 1.1e-08 35.3 0.0 2.7e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 EKX44597.1 - 1.4e-08 34.5 0.8 7e-06 25.7 0.1 2.9 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EKX44597.1 - 4.2e-08 33.0 0.0 1e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 EKX44597.1 - 0.0015 18.3 0.1 1.2 9.0 0.3 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATPgrasp_Ter PF15632.6 EKX44597.1 - 0.038 13.7 0.1 0.27 11.0 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon SATase_N PF06426.14 EKX44597.1 - 0.056 13.8 0.4 8.7 6.8 0.1 3.0 2 0 0 2 2 2 0 Serine acetyltransferase, N-terminal Cupin_4 PF08007.12 EKX44598.1 - 5.2e-56 190.4 0.0 6.6e-46 157.2 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein PITH PF06201.13 EKX44599.1 - 9.3e-34 116.8 0.0 1.1e-33 116.6 0.0 1.1 1 0 0 1 1 1 1 PITH domain Glycos_transf_1 PF00534.20 EKX44600.1 - 0.0065 16.0 0.0 0.16 11.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferases group 1 adh_short PF00106.25 EKX44601.1 - 6.1e-10 38.9 0.4 9.2e-07 28.5 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EKX44601.1 - 5.1e-06 26.2 0.0 4.2e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EKX44601.1 - 0.0012 18.4 0.0 0.049 13.1 0.1 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EKX44601.1 - 0.21 10.7 0.0 0.33 10.0 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain 2OG-FeII_Oxy_3 PF13640.6 EKX44602.1 - 8.4e-15 55.4 0.7 1.6e-14 54.6 0.7 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EKX44602.1 - 3.4e-06 27.5 0.4 2.2e-05 24.9 0.5 2.2 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily CRAL_TRIO PF00650.20 EKX44603.1 - 1.1e-21 77.2 0.0 2.1e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EKX44603.1 - 1.2e-05 25.4 0.0 2.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain FANCF PF11107.8 EKX44603.1 - 0.065 12.4 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) Moulting_cycle PF04870.16 EKX44605.1 - 0.059 12.7 5.4 0.066 12.5 4.8 1.3 1 1 0 1 1 1 0 Moulting cycle FIVAR PF07554.13 EKX44605.1 - 0.14 12.9 6.4 11 6.8 1.0 3.4 2 1 0 3 3 3 0 FIVAR domain Syntaxin_2 PF14523.6 EKX44605.1 - 0.22 11.9 9.6 0.32 11.4 5.8 2.8 2 1 1 3 3 3 0 Syntaxin-like protein DUF1664 PF07889.12 EKX44605.1 - 0.25 11.4 5.5 0.21 11.6 2.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) UvrD_C PF13361.6 EKX44605.1 - 0.37 10.1 6.9 0.59 9.4 6.9 1.4 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF3573 PF12097.8 EKX44605.1 - 0.41 9.4 2.3 0.48 9.2 1.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) DUF745 PF05335.13 EKX44605.1 - 0.48 10.1 6.7 0.56 9.9 5.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Enkurin PF13864.6 EKX44605.1 - 0.66 10.5 4.9 3.1 8.3 4.9 2.2 1 1 0 1 1 1 0 Calmodulin-binding TMPIT PF07851.13 EKX44605.1 - 0.97 8.6 3.5 0.9 8.7 1.7 1.7 1 1 0 1 1 1 0 TMPIT-like protein RSS_P20 PF11757.8 EKX44605.1 - 1 9.9 6.6 19 5.8 6.4 2.8 1 1 1 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain FAM76 PF16046.5 EKX44605.1 - 3.2 7.0 7.3 4.4 6.6 7.3 1.1 1 0 0 1 1 1 0 FAM76 protein WSD PF15613.6 EKX44606.1 - 8e-15 55.1 0.1 8e-15 55.1 0.1 3.0 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif FYRC PF05965.14 EKX44606.1 - 1.3e-12 47.7 0.0 4.4e-12 46.0 0.0 2.0 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 EKX44606.1 - 9.1e-11 41.4 0.7 2.2e-10 40.2 0.1 2.0 2 0 0 2 2 2 1 F/Y-rich N-terminus DDT PF02791.17 EKX44606.1 - 1.1e-06 28.9 1.6 2.5e-06 27.7 1.6 1.6 1 0 0 1 1 1 1 DDT domain ARID PF01388.21 EKX44606.1 - 1.8e-05 25.3 0.7 0.087 13.5 0.0 3.2 2 1 1 3 3 3 2 ARID/BRIGHT DNA binding domain Clathrin_lg_ch PF01086.17 EKX44608.1 - 4.8e-17 62.8 5.3 9.1e-17 61.9 5.2 1.4 1 1 0 1 1 1 1 Clathrin light chain Methyltrn_RNA_4 PF09936.9 EKX44608.1 - 0.5 10.2 1.8 0.76 9.6 1.8 1.2 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase Ank_2 PF12796.7 EKX44609.1 - 1.2e-13 51.5 0.1 2.3e-07 31.3 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX44609.1 - 2.4e-12 47.1 0.0 0.00075 20.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX44609.1 - 1.9e-11 44.0 0.3 5e-05 23.5 0.1 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX44609.1 - 1.8e-05 24.8 0.0 0.07 13.7 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 EKX44609.1 - 6.3e-05 23.2 0.2 0.0026 18.1 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeat SAM_1 PF00536.30 EKX44610.1 - 2.5e-06 27.8 0.0 5.7e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF383 PF04063.14 EKX44610.1 - 0.029 14.0 0.0 0.063 12.9 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF383) SAM_2 PF07647.17 EKX44610.1 - 0.042 14.0 0.0 0.084 13.0 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF591 PF04569.14 EKX44610.1 - 0.26 11.3 2.1 11 6.1 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function MASE3 PF17159.4 EKX44611.1 - 0.019 14.6 0.1 0.025 14.2 0.1 1.1 1 0 0 1 1 1 0 Membrane-associated sensor domain Flavi_NS4A PF01350.17 EKX44611.1 - 0.079 12.9 0.1 0.094 12.6 0.1 1.1 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A Asp PF00026.23 EKX44611.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.4 1 1 0 1 1 1 0 Eukaryotic aspartyl protease Gram_pos_anchor PF00746.21 EKX44611.1 - 1.5 8.8 4.8 8.9 6.4 0.2 2.7 3 0 0 3 3 3 0 LPXTG cell wall anchor motif Med21 PF11221.8 EKX44612.1 - 0.0022 18.2 0.6 0.0029 17.9 0.6 1.2 1 0 0 1 1 1 1 Subunit 21 of Mediator complex MAD PF05557.13 EKX44612.1 - 0.0025 16.3 0.9 0.0034 15.8 0.9 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein AAA_32 PF13654.6 EKX44612.1 - 0.019 13.8 0.1 0.019 13.8 0.1 1.1 1 0 0 1 1 1 0 AAA domain KELK PF15796.5 EKX44612.1 - 0.12 12.9 2.4 0.26 11.8 2.4 1.5 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GNT-I PF03071.15 EKX44612.1 - 0.23 10.2 0.7 0.31 9.7 0.7 1.1 1 0 0 1 1 1 0 GNT-I family Seryl_tRNA_N PF02403.22 EKX44612.1 - 0.69 10.2 6.1 1.2 9.4 6.1 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Fzo_mitofusin PF04799.13 EKX44612.1 - 0.83 9.2 3.5 5 6.7 3.5 2.1 1 1 0 1 1 1 0 fzo-like conserved region Fig1 PF12351.8 EKX44612.1 - 0.85 9.5 5.2 6.7 6.6 0.1 2.6 3 0 0 3 3 3 0 Ca2+ regulator and membrane fusion protein Fig1 DUF948 PF06103.11 EKX44612.1 - 8.8 6.7 10.2 3.9 7.8 5.7 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF498 PF04430.14 EKX44614.1 - 2.5e-27 95.1 0.0 2.9e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Nup54_57_C PF18570.1 EKX44614.1 - 0.022 14.3 0.1 0.04 13.5 0.1 1.4 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain Adap_comp_sub PF00928.21 EKX44615.1 - 5.3e-86 288.3 0.0 1.6e-85 286.7 0.1 1.6 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EKX44615.1 - 1.9e-05 24.6 0.3 3.2e-05 23.9 0.3 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EKX44615.1 - 4.2e-05 23.1 0.0 0.0003 20.3 0.0 2.0 1 1 1 2 2 2 1 Muniscin C-terminal mu homology domain CAP_C PF08603.11 EKX44616.1 - 1.4e-10 41.0 0.0 2.6e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Phage_T4_Ndd PF06591.11 EKX44616.1 - 0.07 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) TMEM43 PF07787.12 EKX44617.1 - 2.8e-16 59.7 0.4 1.3e-10 41.1 0.0 2.2 2 0 0 2 2 2 2 Transmembrane protein 43 HMG_CoA_synt_N PF01154.17 EKX44618.1 - 2.5e-79 265.2 0.2 3.4e-79 264.7 0.2 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 EKX44618.1 - 3.9e-72 243.2 0.4 7.7e-71 239.0 0.4 2.1 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal YGGT PF02325.17 EKX44619.1 - 1.5e-11 44.5 5.3 2.2e-11 44.0 5.3 1.3 1 0 0 1 1 1 1 YGGT family PX PF00787.24 EKX44622.1 - 3e-15 56.2 0.0 4.8e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 PX domain Abhydrolase_6 PF12697.7 EKX44623.1 - 1.7e-10 41.9 0.0 5.1e-09 37.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EKX44623.1 - 2.9e-08 33.7 0.0 4.1e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EKX44623.1 - 3e-05 23.4 0.0 5.4e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EKX44623.1 - 0.0048 17.0 0.0 0.0079 16.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain UPF0227 PF05728.12 EKX44623.1 - 0.0066 16.4 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) PGAP1 PF07819.13 EKX44623.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 EKX44623.1 - 0.019 14.9 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF900 PF05990.12 EKX44623.1 - 0.043 13.3 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LIDHydrolase PF10230.9 EKX44623.1 - 0.083 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 EKX44623.1 - 0.086 12.6 0.1 4.1 7.2 0.1 2.2 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 EKX44623.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 EKX44623.1 - 0.12 11.3 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase Ephrin_rec_like PF07699.13 EKX44624.1 - 1.6e-14 53.4 29.2 1.6e-07 30.9 3.2 3.8 2 1 2 4 4 4 4 Putative ephrin-receptor like NCD3G PF07562.14 EKX44624.1 - 7.5e-07 29.0 19.9 0.033 14.2 0.8 3.7 3 1 0 3 3 3 3 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX44624.1 - 0.0016 18.8 17.6 0.019 15.4 0.8 4.6 2 2 2 4 4 4 2 TNFR/NGFR cysteine-rich region Sp38 PF07354.12 EKX44624.1 - 0.024 14.1 12.8 0.076 12.4 3.1 2.2 1 1 1 2 2 2 0 Zona-pellucida-binding protein (Sp38) Pkinase_Tyr PF07714.17 EKX44625.1 - 2.4e-41 141.8 0.0 2.9e-41 141.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX44625.1 - 2.1e-36 125.6 0.0 2.7e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EKX44625.1 - 0.01 15.2 0.0 0.014 14.7 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX44625.1 - 0.037 13.9 0.0 0.055 13.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family PAS_10 PF13596.6 EKX44626.1 - 1.3e-06 29.0 0.0 5.4 7.7 0.0 4.5 1 1 3 5 5 5 3 PAS domain Drf_FH1 PF06346.12 EKX44626.1 - 0.00036 20.3 25.5 0.097 12.4 3.5 2.9 1 1 1 2 2 2 2 Formin Homology Region 1 PKD_3 PF16820.5 EKX44626.1 - 0.0015 18.2 0.3 44 3.9 0.0 4.8 2 1 1 5 5 5 0 PKD-like domain FAM47 PF14642.6 EKX44626.1 - 0.0018 17.9 6.3 0.25 10.9 0.9 2.7 1 1 2 3 3 3 3 FAM47 family Papilin_u7 PF16626.5 EKX44626.1 - 0.016 15.8 11.0 20 5.9 0.4 5.4 1 1 3 5 5 5 0 Linking region between Kunitz_BPTI and I-set on papilin DUF5476 PF17570.2 EKX44626.1 - 0.025 15.0 24.9 0.62 10.5 0.5 6.2 2 2 4 6 6 6 0 Family of unknown function (DUF5476) SOBP PF15279.6 EKX44626.1 - 0.035 14.7 9.2 2.2 8.8 0.7 3.0 1 1 2 3 3 3 0 Sine oculis-binding protein PreAtp-grasp PF18604.1 EKX44626.1 - 0.073 12.7 0.8 11 5.7 0.1 3.2 1 1 2 4 4 4 0 Pre ATP-grasp domain UPF0220 PF05255.11 EKX44627.1 - 8.4e-18 64.5 3.7 8.4e-15 54.7 0.6 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0220) CRAL_TRIO PF00650.20 EKX44628.1 - 3.9e-20 72.2 0.0 5.1e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain FPL PF09758.9 EKX44629.1 - 3.1e-55 186.2 1.5 3.6e-55 186.0 1.5 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein DUF3573 PF12097.8 EKX44629.1 - 0.15 10.8 0.3 0.2 10.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) LMWPc PF01451.21 EKX44630.1 - 2.4e-09 37.7 0.0 3.2e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Collagen PF01391.18 EKX44631.1 - 2.3e-15 56.1 71.7 2e-09 37.1 34.2 2.4 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) MCR_C PF04609.12 EKX44631.1 - 0.02 14.0 1.7 0.031 13.4 1.7 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C RmuC PF02646.16 EKX44631.1 - 0.027 13.6 3.4 0.039 13.1 3.4 1.1 1 0 0 1 1 1 0 RmuC family Ima1_N PF09779.9 EKX44631.1 - 0.062 14.2 0.0 0.11 13.4 0.0 1.4 1 0 0 1 1 1 0 Ima1 N-terminal domain DUF3450 PF11932.8 EKX44631.1 - 0.13 11.6 3.9 0.2 10.9 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) OmpH PF03938.14 EKX44631.1 - 0.13 12.6 5.5 0.28 11.5 5.5 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DLP_helical PF18709.1 EKX44631.1 - 0.32 10.2 3.6 0.44 9.7 3.6 1.1 1 0 0 1 1 1 0 Dynamin-like helical domain Fib_alpha PF08702.10 EKX44631.1 - 0.48 10.6 4.7 0.74 10.0 4.7 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF684 PF05075.14 EKX44631.1 - 0.56 9.1 3.6 0.8 8.6 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF684) TMPIT PF07851.13 EKX44631.1 - 0.89 8.7 4.2 1.2 8.3 4.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF936 PF06075.12 EKX44631.1 - 1.3 7.9 4.7 1.7 7.4 4.7 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) FAM76 PF16046.5 EKX44631.1 - 8.2 5.7 13.2 1 8.6 9.2 1.4 1 1 0 1 1 1 0 FAM76 protein Turandot PF07240.11 EKX44633.1 - 0.035 14.1 0.0 0.049 13.6 0.0 1.2 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot AAA_12 PF13087.6 EKX44634.1 - 2.9e-23 82.6 0.1 3.1e-23 82.5 0.1 1.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EKX44634.1 - 1.4e-07 31.2 0.1 3.5e-07 29.9 0.1 1.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EKX44634.1 - 0.016 15.0 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase UvrD_C PF13361.6 EKX44634.1 - 0.054 12.9 0.1 0.068 12.5 0.1 1.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Mer2 PF09074.10 EKX44635.1 - 0.00095 19.0 11.1 0.0027 17.5 2.0 2.5 2 1 1 3 3 3 2 Mer2 TPR_2 PF07719.17 EKX44635.1 - 0.0025 17.8 0.1 2.8 8.3 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat Syntaxin_2 PF14523.6 EKX44635.1 - 0.0029 18.0 16.3 0.022 15.1 3.8 3.3 2 1 1 3 3 3 3 Syntaxin-like protein Rx_N PF18052.1 EKX44635.1 - 0.012 15.8 0.8 0.012 15.8 0.8 2.9 2 2 0 2 2 2 0 Rx N-terminal domain zf-C4H2 PF10146.9 EKX44635.1 - 2 8.7 17.8 37 4.5 17.8 2.2 1 1 0 1 1 1 0 Zinc finger-containing protein MAS20 PF02064.15 EKX44635.1 - 2.2 8.4 13.5 0.42 10.7 5.3 2.8 2 1 1 3 3 3 0 MAS20 protein import receptor ESM4 PF15952.5 EKX44635.1 - 3.9 7.9 10.8 0.19 12.2 3.6 2.2 1 1 1 2 2 2 0 Enhancer of split M4 family ABC_tran_Xtn PF12848.7 EKX44635.1 - 4.4 7.4 16.4 0.65 10.1 3.2 3.2 2 1 0 2 2 2 0 ABC transporter AtpR PF12966.7 EKX44636.1 - 7.3 7.1 10.1 0.26 11.8 2.5 2.3 2 1 0 2 2 2 0 N-ATPase, AtpR subunit Na_H_antiport_2 PF13726.6 EKX44636.1 - 9.4 6.5 8.6 4 7.6 0.3 3.0 1 1 1 3 3 3 0 Na+-H+ antiporter family DUF1635 PF07795.11 EKX44637.1 - 0.014 15.3 3.7 0.014 15.3 3.7 3.8 2 2 1 4 4 4 0 Protein of unknown function (DUF1635) VPS11_C PF12451.8 EKX44637.1 - 0.031 14.5 3.1 1.1 9.6 0.0 3.5 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal DUF4391 PF14335.6 EKX44637.1 - 0.096 12.4 0.3 0.096 12.4 0.3 4.4 4 2 1 5 5 5 0 Domain of unknown function (DUF4391) DUF948 PF06103.11 EKX44637.1 - 0.38 11.0 11.2 5.7 7.3 0.3 4.2 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) YgaB PF14182.6 EKX44637.1 - 0.69 10.3 20.5 0.12 12.8 3.5 4.6 3 1 1 4 4 4 0 YgaB-like protein CobU PF02283.16 EKX44637.1 - 5.8 6.4 9.4 1.3 8.5 0.8 2.9 2 1 1 3 3 3 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Filament PF00038.21 EKX44637.1 - 6 6.3 36.8 2.9 7.4 2.8 3.7 2 1 0 2 2 2 0 Intermediate filament protein DUF1283 PF06932.11 EKX44638.1 - 0.029 14.6 0.7 3.8 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1283) HTH_23 PF13384.6 EKX44638.1 - 0.032 14.0 0.0 0.064 13.1 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.6 EKX44638.1 - 0.071 13.1 0.1 0.2 11.7 0.1 1.9 1 0 0 1 1 1 0 Winged helix-turn helix Phage_Cox PF10743.9 EKX44638.1 - 0.074 13.2 0.1 0.13 12.3 0.1 1.5 1 1 0 1 1 1 0 Regulatory phage protein cox Sigma70_r4 PF04545.16 EKX44638.1 - 0.1 12.2 0.0 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 KorB PF08535.10 EKX44638.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 KorB domain HTH_23 PF13384.6 EKX44639.1 - 0.047 13.5 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_29 PF13551.6 EKX44639.1 - 0.048 13.7 0.1 0.12 12.4 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn helix Sigma70_r4 PF04545.16 EKX44639.1 - 0.096 12.2 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Zn_clus PF00172.18 EKX44640.1 - 3.2e-12 46.4 33.8 2e-06 27.8 11.8 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain NodZ PF05830.11 EKX44641.1 - 0.0029 16.5 0.3 0.03 13.1 0.3 2.4 1 1 0 1 1 1 1 Nodulation protein Z (NodZ) TPR_2 PF07719.17 EKX44641.1 - 0.029 14.5 0.1 4.8 7.5 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat O-FucT PF10250.9 EKX44641.1 - 0.093 12.4 2.5 0.96 9.1 2.5 2.4 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase TcfC PF16967.5 EKX44642.1 - 0.19 11.2 0.1 0.54 9.8 0.0 1.8 2 0 0 2 2 2 0 E-set like domain Nup35_RRM_2 PF14605.6 EKX44644.1 - 2.5e-06 27.4 0.0 4.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 EKX44644.1 - 1.3e-05 25.1 0.0 7.4e-05 22.7 0.0 2.1 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif TFR_dimer PF04253.15 EKX44645.1 - 1.2e-24 86.7 0.0 2e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EKX44645.1 - 2.2e-22 79.7 0.0 4e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EKX44645.1 - 3.1e-14 52.7 0.0 1.3e-13 50.8 0.0 2.0 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 EKX44645.1 - 0.022 14.5 0.0 0.04 13.6 0.0 1.4 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 Nicastrin PF05450.15 EKX44645.1 - 0.039 13.4 0.0 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 Nicastrin FA_desaturase PF00487.24 EKX44646.1 - 1.7e-28 100.1 14.9 2.7e-28 99.5 14.9 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Ribosomal_L7Ae PF01248.26 EKX44647.1 - 6.8e-19 67.4 0.3 1.4e-18 66.4 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family AMPK1_CBM PF16561.5 EKX44647.1 - 0.05 13.8 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase Med9 PF07544.13 EKX44648.1 - 0.082 13.0 2.8 0.22 11.6 2.8 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 V_ATPase_I PF01496.19 EKX44648.1 - 0.2 9.5 1.6 0.31 8.9 1.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Latarcin PF10279.9 EKX44648.1 - 0.33 11.4 2.3 1.4 9.4 1.6 2.3 2 0 0 2 2 2 0 Latarcin precursor OmpH PF03938.14 EKX44648.1 - 0.33 11.3 6.8 0.82 10.0 2.1 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SIMPL PF04402.14 EKX44648.1 - 0.42 11.0 7.2 0.36 11.3 1.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF541) Prefoldin_2 PF01920.20 EKX44648.1 - 0.48 10.4 5.2 0.25 11.3 1.3 2.2 2 0 0 2 2 2 0 Prefoldin subunit GrpE PF01025.19 EKX44648.1 - 5.1 6.7 7.4 4.2 7.0 4.1 2.3 2 0 0 2 2 2 0 GrpE zf-Tim10_DDP PF02953.15 EKX44649.1 - 1.7e-09 37.2 7.2 2.2e-09 36.8 7.2 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger TRM13 PF05206.14 EKX44649.1 - 0.0083 15.7 0.9 0.0095 15.5 0.9 1.1 1 0 0 1 1 1 1 Methyltransferase TRM13 Carb_anhydrase PF00194.21 EKX44650.1 - 1.2e-41 142.9 0.2 1.5e-40 139.3 0.2 2.3 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase cobW PF02492.19 EKX44651.1 - 1.9e-41 141.6 0.4 2.6e-41 141.1 0.4 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EKX44651.1 - 2e-22 78.9 0.0 5.3e-22 77.6 0.0 1.8 1 1 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain Viral_helicase1 PF01443.18 EKX44651.1 - 0.0021 17.8 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 EKX44651.1 - 0.0095 16.5 0.3 0.036 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 EKX44651.1 - 0.032 14.2 0.1 0.077 13.0 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 EKX44651.1 - 0.032 14.1 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MobB PF03205.14 EKX44651.1 - 0.041 13.8 0.1 0.12 12.3 0.1 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 EKX44651.1 - 0.041 14.0 0.0 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EKX44651.1 - 0.048 13.6 2.7 2.4 8.0 0.1 2.5 2 1 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 EKX44651.1 - 0.061 13.7 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain SPX PF03105.19 EKX44651.1 - 0.21 11.4 3.7 0.29 11.0 3.7 1.2 1 0 0 1 1 1 0 SPX domain AAA_22 PF13401.6 EKX44651.1 - 0.29 11.4 0.8 0.93 9.8 0.1 2.1 1 1 0 2 2 2 0 AAA domain Wyosine_form PF08608.12 EKX44652.1 - 2.2e-22 79.1 0.1 4.4e-22 78.2 0.1 1.5 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 EKX44652.1 - 7.6e-10 39.4 0.0 2.4e-09 37.8 0.0 1.9 1 1 0 1 1 1 1 Radical SAM superfamily FAD_binding_1 PF00667.20 EKX44653.1 - 0.077 12.5 0.0 0.093 12.3 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain RWP-RK PF02042.15 EKX44654.1 - 5.4e-10 39.1 0.1 1.2e-09 37.9 0.1 1.6 1 0 0 1 1 1 1 RWP-RK domain HflK_N PF12221.8 EKX44654.1 - 0.018 15.0 0.8 0.044 13.8 0.8 1.6 1 0 0 1 1 1 0 Bacterial membrane protein N terminal TFIIA PF03153.13 EKX44654.1 - 0.68 9.9 16.8 0.83 9.6 16.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ZZ PF00569.17 EKX44655.1 - 4.4e-07 29.6 15.5 1.8e-06 27.7 5.2 2.9 2 1 0 2 2 2 2 Zinc finger, ZZ type RCC1_2 PF13540.6 EKX44655.1 - 1e-05 25.2 0.7 1e-05 25.2 0.7 2.9 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EKX44655.1 - 0.059 14.0 0.3 2.9 8.6 0.0 2.8 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat C1_2 PF03107.16 EKX44655.1 - 1.2 9.5 7.5 0.92 9.9 2.9 2.9 3 0 0 3 3 3 0 C1 domain SET PF00856.28 EKX44656.1 - 2.7e-05 24.6 0.0 0.0001 22.8 0.0 1.9 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 EKX44656.1 - 0.001 19.7 0.3 0.006 17.3 0.0 2.3 3 0 0 3 3 3 1 Rubisco LSMT substrate-binding RCC1_2 PF13540.6 EKX44656.1 - 0.0013 18.4 0.3 0.0027 17.5 0.3 1.5 1 0 0 1 1 1 1 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EKX44656.1 - 0.011 16.3 0.2 0.28 11.9 0.0 2.5 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat Lipase PF00151.19 EKX44656.1 - 0.1 11.9 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Lipase COMP PF11598.8 EKX44657.1 - 0.74 10.3 4.5 5 7.7 0.1 3.4 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Fib_alpha PF08702.10 EKX44657.1 - 6 7.1 11.9 0.74 10.0 0.1 4.3 3 2 1 4 4 4 0 Fibrinogen alpha/beta chain family ICMT PF04140.14 EKX44659.1 - 4.1e-27 94.4 0.0 5.9e-27 93.9 0.0 1.2 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.12 EKX44659.1 - 1.4e-05 24.7 0.2 1.8e-05 24.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 EKX44659.1 - 3.7e-05 24.1 0.3 3.7e-05 24.1 0.3 2.1 2 2 0 2 2 2 1 Phospholipid methyltransferase DSS1_SEM1 PF05160.13 EKX44662.1 - 1.5e-09 37.8 13.5 1.9e-09 37.4 13.5 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family DUF2947 PF11163.8 EKX44662.1 - 0.011 15.6 2.7 0.012 15.4 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) Ribonuclease_T2 PF00445.18 EKX44662.1 - 0.041 14.1 1.1 0.051 13.8 1.1 1.1 1 0 0 1 1 1 0 Ribonuclease T2 family Carn_acyltransf PF00755.20 EKX44663.1 - 1e-179 599.0 0.0 1.2e-179 598.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase YABBY PF04690.13 EKX44664.1 - 1.8e-15 57.9 0.5 1.8e-15 57.8 0.5 1.1 1 0 0 1 1 1 1 YABBY protein HMG_box PF00505.19 EKX44664.1 - 2e-05 24.9 2.2 3.3e-05 24.2 2.2 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EKX44664.1 - 0.0014 19.2 2.2 0.0023 18.5 2.0 1.5 1 1 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 EKX44664.1 - 0.0067 17.0 5.3 0.0081 16.7 5.3 1.4 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 zf-C3HC4 PF00097.25 EKX44665.1 - 3.3e-09 36.5 8.7 3.3e-09 36.5 8.7 3.0 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX44665.1 - 2e-08 34.1 5.2 2e-08 34.1 5.2 2.7 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EKX44665.1 - 2.2e-08 34.1 9.1 2.2e-08 34.1 9.1 3.2 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EKX44665.1 - 6e-08 32.4 9.4 6e-08 32.4 9.4 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX44665.1 - 7.6e-07 29.4 9.0 7.6e-07 29.4 9.0 3.1 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 EKX44665.1 - 2.9e-06 27.0 6.4 2.9e-06 27.0 6.4 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX44665.1 - 0.00015 21.7 7.8 0.00015 21.7 7.8 3.7 3 1 0 3 3 3 1 zinc-RING finger domain zf-Nse PF11789.8 EKX44665.1 - 0.00091 19.0 4.5 0.0018 18.0 4.5 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 EKX44665.1 - 0.0019 18.3 5.8 0.0019 18.3 5.8 3.0 3 0 0 3 3 3 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 EKX44665.1 - 0.0028 17.5 2.7 0.0028 17.5 2.7 2.3 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 EKX44665.1 - 0.028 14.5 2.2 0.028 14.5 2.2 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger BUD22 PF09073.10 EKX44665.1 - 0.065 12.6 13.7 0.093 12.1 13.7 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 EKX44665.1 - 0.27 9.5 15.8 0.36 9.1 15.8 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-MIZ PF02891.20 EKX44665.1 - 0.63 9.8 9.6 0.24 11.2 6.5 2.0 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_11 PF17123.5 EKX44665.1 - 1.9 8.3 13.6 0.11 12.3 4.9 2.8 2 0 0 2 2 2 0 RING-like zinc finger RR_TM4-6 PF06459.12 EKX44665.1 - 2.5 7.9 6.9 5.3 6.8 6.9 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DAO PF01266.24 EKX44666.1 - 5.7e-25 88.6 0.0 6.8e-25 88.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EKX44666.1 - 1.4e-05 24.5 0.0 0.074 12.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EKX44666.1 - 0.00022 21.4 0.0 0.0011 19.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EKX44666.1 - 0.0014 18.0 0.0 0.12 11.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EKX44666.1 - 0.0045 17.0 0.3 0.13 12.3 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EKX44666.1 - 0.024 13.4 0.1 1.9 7.1 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 EKX44666.1 - 0.051 14.1 0.1 0.25 11.9 0.0 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EKX44666.1 - 0.052 12.7 0.0 3.6 6.6 0.0 2.4 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 EKX44666.1 - 0.077 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 EKX44666.1 - 0.079 12.0 0.0 1.3 8.0 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NHR2 PF08788.11 EKX44666.1 - 0.12 12.2 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 NHR2 domain like FAD_binding_3 PF01494.19 EKX44666.1 - 0.14 11.3 0.0 0.41 9.8 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.16 EKX44666.1 - 0.19 11.4 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA IPPT PF01715.17 EKX44667.1 - 3.7e-57 193.8 0.0 9.4e-57 192.4 0.0 1.6 2 0 0 2 2 2 1 IPP transferase IPT PF01745.16 EKX44667.1 - 1.3e-06 28.0 0.0 2.5e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Isopentenyl transferase AAA_23 PF13476.6 EKX44667.1 - 0.0014 19.2 5.9 0.97 9.9 5.2 2.2 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EKX44667.1 - 0.0015 18.7 2.2 0.0016 18.6 0.0 2.2 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EKX44667.1 - 0.026 14.9 4.2 0.04 14.3 0.0 2.6 2 1 1 3 3 3 0 AAA ATPase domain PTPRCAP PF15713.5 EKX44667.1 - 0.039 14.3 7.2 0.084 13.2 7.2 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated AAA_18 PF13238.6 EKX44667.1 - 0.041 14.4 1.5 0.14 12.7 0.0 2.5 2 1 1 3 3 3 0 AAA domain Cytidylate_kin PF02224.18 EKX44667.1 - 0.057 13.1 0.0 0.057 13.1 0.0 1.7 2 0 0 2 2 2 0 Cytidylate kinase ABC_tran PF00005.27 EKX44667.1 - 0.059 13.9 0.2 0.31 11.5 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_14 PF13173.6 EKX44667.1 - 0.06 13.4 0.5 0.21 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EKX44667.1 - 0.071 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Hpr_kinase_C PF07475.12 EKX44667.1 - 0.084 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain RNA_helicase PF00910.22 EKX44667.1 - 0.16 12.4 0.0 3.2 8.2 0.0 2.8 3 0 0 3 3 3 0 RNA helicase DUF4837 PF16125.5 EKX44667.1 - 0.26 10.3 3.1 0.42 9.6 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4837) RGS-like PF09128.11 EKX44669.1 - 0.18 11.5 0.1 0.27 10.9 0.1 1.3 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain MORN PF02493.20 EKX44670.1 - 1.4e-42 141.1 56.9 1.5e-07 30.9 1.0 8.5 8 0 0 8 8 8 7 MORN repeat zf-RanBP PF00641.18 EKX44671.1 - 4.6e-05 22.6 7.4 0.0001 21.5 7.4 1.6 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others CSD PF00313.22 EKX44671.1 - 0.00019 21.2 0.0 0.00058 19.7 0.0 1.8 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain CENP-T_C PF15511.6 EKX44673.1 - 4.1e-09 36.5 0.1 5e-09 36.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EKX44673.1 - 0.0001 22.6 0.1 0.00014 22.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 EKX44673.1 - 0.0001 22.4 0.2 0.00014 21.9 0.2 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 EKX44673.1 - 0.00021 21.7 0.3 0.00024 21.5 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EKX44673.1 - 0.00042 20.5 0.1 0.00064 19.9 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EKX44673.1 - 0.0073 16.4 0.0 0.0085 16.2 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EKX44673.1 - 0.013 15.5 0.1 0.02 14.9 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated RRM_1 PF00076.22 EKX44674.1 - 1.3e-64 213.9 5.8 1.3e-14 53.7 0.0 6.2 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 EKX44674.1 - 9.9e-08 31.9 1.5 0.11 12.3 0.2 4.6 4 0 0 4 4 4 3 Rrp7 RRM-like N-terminal domain RRM_3 PF08777.11 EKX44674.1 - 5.2e-05 23.2 0.9 0.069 13.2 0.0 5.1 5 0 0 5 5 5 1 RNA binding motif Nup35_RRM_2 PF14605.6 EKX44674.1 - 0.00043 20.2 0.1 2.9 8.0 0.0 4.5 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EKX44674.1 - 0.00054 19.8 0.0 2.2 8.2 0.0 3.9 4 0 0 4 4 4 1 Occluded RNA-recognition motif RRM_7 PF16367.5 EKX44674.1 - 0.0029 17.7 0.1 12 6.1 0.1 5.0 4 2 0 4 4 4 1 RNA recognition motif TRL PF13146.6 EKX44674.1 - 0.031 14.5 0.1 0.09 13.1 0.1 1.7 1 0 0 1 1 1 0 TRL-like protein family RRM_1 PF00076.22 EKX44675.1 - 6.8e-11 41.8 0.0 1.2e-10 41.1 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PDZ_2 PF13180.6 EKX44676.1 - 6e-07 29.7 0.1 8.8e-07 29.2 0.1 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX44676.1 - 5.8e-05 22.8 0.1 5.8e-05 22.8 0.1 1.7 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX44676.1 - 0.00012 22.3 0.1 0.00029 21.1 0.1 1.6 2 0 0 2 2 2 1 PDZ domain MgsA_C PF12002.8 EKX44677.1 - 1.8e-57 193.9 0.0 3.3e-57 193.1 0.0 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 EKX44677.1 - 2.9e-19 69.2 0.1 7.2e-19 67.9 0.1 1.7 1 0 0 1 1 1 1 AAA C-terminal domain UBA PF00627.31 EKX44677.1 - 8e-05 22.5 0.0 0.00038 20.3 0.0 2.2 2 0 0 2 2 2 1 UBA/TS-N domain AAA PF00004.29 EKX44677.1 - 0.00024 21.5 0.1 0.0075 16.7 0.1 2.5 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EKX44677.1 - 0.00041 20.9 0.1 0.0014 19.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EKX44677.1 - 0.001 18.9 0.0 0.0041 16.9 0.0 1.9 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain CUE PF02845.16 EKX44677.1 - 0.0021 17.7 0.0 0.0059 16.3 0.0 1.8 1 0 0 1 1 1 1 CUE domain Rad17 PF03215.15 EKX44677.1 - 0.0047 16.9 0.0 0.0087 16.0 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EKX44677.1 - 0.0072 16.7 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EKX44677.1 - 0.025 14.6 0.0 0.061 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EKX44677.1 - 0.095 12.9 0.0 0.33 11.1 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_22 PF13401.6 EKX44677.1 - 0.14 12.5 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EKX44677.1 - 0.15 12.6 0.1 0.41 11.2 0.1 1.6 1 0 0 1 1 1 0 ABC transporter DUF815 PF05673.13 EKX44677.1 - 0.19 10.9 0.0 0.33 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 EKX44677.1 - 0.24 11.6 0.9 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain PDZ_6 PF17820.1 EKX44678.1 - 0.0013 18.6 0.3 0.024 14.5 0.3 2.5 1 1 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX44678.1 - 0.0022 18.3 0.0 0.0041 17.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain DUF924 PF06041.11 EKX44678.1 - 0.019 15.1 2.1 0.038 14.1 2.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF924) DUF3357 PF11837.8 EKX44678.1 - 0.055 13.9 0.0 0.34 11.4 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) DUF4834 PF16118.5 EKX44678.1 - 8.7 7.4 7.4 11 7.0 1.5 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) Pkinase PF00069.25 EKX44679.1 - 2.6e-44 151.6 0.0 3.2e-44 151.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX44679.1 - 2.3e-38 132.0 0.0 3.9e-38 131.2 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX44679.1 - 1.1e-05 24.4 0.0 1.6e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX44679.1 - 0.017 15.0 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family AHSA1 PF08327.11 EKX44680.1 - 6.3e-14 52.3 0.0 1.4e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Aha1_N PF09229.11 EKX44680.1 - 9.7e-14 51.8 0.2 1.7e-13 51.0 0.2 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal zf-CHC2 PF01807.20 EKX44680.1 - 0.088 12.6 0.1 0.22 11.3 0.1 1.7 1 0 0 1 1 1 0 CHC2 zinc finger AAA PF00004.29 EKX44681.1 - 2.8e-44 150.7 0.0 4.1e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX44681.1 - 5.3e-06 26.9 0.4 0.0012 19.2 0.1 2.8 1 1 2 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EKX44681.1 - 0.00032 20.5 0.0 0.00061 19.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EKX44681.1 - 0.00039 20.7 0.0 0.0017 18.6 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 EKX44681.1 - 0.0021 18.1 0.1 0.0089 16.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EKX44681.1 - 0.0034 17.6 0.0 0.0065 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EKX44681.1 - 0.0042 17.6 0.0 0.0078 16.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EKX44681.1 - 0.0042 16.7 0.1 0.016 14.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EKX44681.1 - 0.0052 16.9 0.0 0.014 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 EKX44681.1 - 0.0056 15.9 0.0 0.008 15.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EKX44681.1 - 0.0096 15.3 0.1 0.019 14.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EKX44681.1 - 0.0098 16.3 0.0 0.016 15.6 0.0 1.3 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 EKX44681.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.4 1 1 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EKX44681.1 - 0.012 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 EKX44681.1 - 0.019 14.6 0.0 0.04 13.6 0.0 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase PF06745.13 EKX44681.1 - 0.029 13.7 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_11 PF13086.6 EKX44681.1 - 0.039 13.7 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EKX44681.1 - 0.046 13.7 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 EKX44681.1 - 0.063 12.5 0.0 0.18 11.0 0.1 1.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_lid_3 PF17862.1 EKX44681.1 - 0.064 13.1 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 AAA+ lid domain Sigma54_activ_2 PF14532.6 EKX44681.1 - 0.07 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 EKX44681.1 - 0.073 12.8 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EKX44681.1 - 0.075 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EKX44681.1 - 0.1 12.8 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EKX44681.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.17 EKX44681.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 EKX44681.1 - 0.19 12.1 0.0 0.31 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EKX44681.1 - 0.24 10.5 0.0 0.47 9.6 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF815) FoP_duplication PF13865.6 EKX44681.1 - 0.33 11.5 2.6 0.78 10.3 2.6 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DUF4315 PF14193.6 EKX44682.1 - 0.084 12.9 0.5 6.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) WD40 PF00400.32 EKX44683.1 - 3e-21 75.3 13.2 6.6e-05 23.6 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX44683.1 - 3.3e-10 40.1 0.0 0.03 14.6 0.0 4.1 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EKX44683.1 - 0.00023 20.6 0.0 0.015 14.6 0.0 2.5 2 1 0 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 EKX44683.1 - 0.012 14.6 0.2 0.044 12.7 0.1 1.9 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_C1 PF00112.23 EKX44685.1 - 7.4e-69 232.2 3.8 1e-68 231.7 3.8 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EKX44685.1 - 4.8e-10 39.7 0.0 7.7e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EKX44685.1 - 0.00082 18.3 1.9 0.048 12.4 0.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Propeptide_C1 PF08127.13 EKX44685.1 - 0.0026 17.6 0.0 0.0066 16.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase family C1 propeptide PNK3P PF08645.11 EKX44686.1 - 5.2e-26 91.3 0.0 7.7e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase BRCT_2 PF16589.5 EKX44686.1 - 7.3e-08 32.7 0.0 1.4e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Glyco_transf_11 PF01531.16 EKX44687.1 - 4.9e-18 65.4 0.1 3.2e-17 62.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 11 DEAD PF00270.29 EKX44688.1 - 5.8e-42 143.4 0.1 8.1e-42 143.0 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX44688.1 - 7.3e-29 100.4 0.6 8.9e-28 96.9 0.3 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EKX44688.1 - 0.0053 16.0 0.1 0.0079 15.4 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 EKX44688.1 - 0.0086 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Thx PF17070.5 EKX44689.1 - 0.00036 20.5 5.7 0.00058 19.9 5.7 1.4 1 0 0 1 1 1 1 30S ribosomal protein Thx RPS31 PF17067.5 EKX44689.1 - 0.13 12.5 1.3 0.13 12.4 1.3 1.3 1 1 0 1 1 1 0 Ribosomal protein S31e TPR_2 PF07719.17 EKX44690.1 - 7.4e-24 81.9 27.1 0.00017 21.5 0.2 10.9 10 1 1 11 11 11 7 Tetratricopeptide repeat TPR_1 PF00515.28 EKX44690.1 - 1e-21 75.8 22.6 6.8e-06 25.7 0.1 10.4 11 0 0 11 11 10 4 Tetratricopeptide repeat DnaJ PF00226.31 EKX44690.1 - 6.5e-19 67.8 0.5 2.5e-18 65.9 0.1 2.4 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.6 EKX44690.1 - 3.2e-16 59.6 21.6 0.00013 22.4 0.7 8.3 7 2 1 8 8 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 EKX44690.1 - 1e-13 50.7 9.8 0.0088 15.7 0.0 7.6 7 0 0 7 7 7 3 TPR repeat TPR_14 PF13428.6 EKX44690.1 - 2.8e-11 43.3 23.4 0.025 15.4 0.0 10.1 8 3 3 11 11 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX44690.1 - 1.6e-10 41.4 7.8 3.6 8.3 0.1 7.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX44690.1 - 4.7e-08 32.6 13.8 0.53 10.6 0.2 8.5 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX44690.1 - 8.2e-08 31.8 5.4 19 5.6 0.0 7.6 7 0 0 7 7 6 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EKX44690.1 - 2.5e-07 30.7 5.3 0.00046 20.2 0.1 4.0 3 1 1 4 4 4 2 Putative TPR-like repeat TPR_12 PF13424.6 EKX44690.1 - 5.6e-07 29.8 29.1 5.8e-05 23.3 3.1 8.7 7 3 2 9 9 8 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX44690.1 - 0.00048 20.1 2.0 1 9.5 0.1 5.3 6 0 0 6 6 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 EKX44690.1 - 0.0031 17.6 11.3 0.24 11.6 0.6 5.9 5 1 1 6 6 6 1 Tetratricopeptide repeat BTAD PF03704.17 EKX44690.1 - 0.0043 17.5 15.3 0.051 14.0 3.6 5.0 2 1 3 5 5 5 1 Bacterial transcriptional activator domain TPR_6 PF13174.6 EKX44690.1 - 0.0071 16.9 12.1 8.3 7.3 0.0 8.2 9 0 0 9 9 8 0 Tetratricopeptide repeat OEP PF02321.18 EKX44690.1 - 0.042 13.7 3.9 0.15 11.9 3.9 1.9 1 0 0 1 1 1 0 Outer membrane efflux protein ANAPC3 PF12895.7 EKX44690.1 - 0.067 13.4 26.5 0.091 13.0 3.7 6.3 4 3 3 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EKX44690.1 - 0.078 13.4 3.1 27 5.4 0.0 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat MIT PF04212.18 EKX44690.1 - 0.088 12.9 22.7 0.24 11.5 2.1 5.9 6 1 0 6 6 5 0 MIT (microtubule interacting and transport) domain SesA PF17107.5 EKX44690.1 - 0.76 10.0 8.9 0.31 11.2 0.3 4.0 4 1 0 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TOM20_plant PF06552.12 EKX44690.1 - 3.1 7.5 10.2 0.088 12.5 0.5 3.2 3 0 0 3 3 2 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_4 PF07721.14 EKX44690.1 - 3.4 8.6 15.3 28 5.7 0.1 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat ParA PF10609.9 EKX44691.1 - 1.2e-90 303.2 0.2 1.8e-90 302.7 0.2 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EKX44691.1 - 1e-11 44.9 0.0 5.9e-11 42.5 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 EKX44691.1 - 7.3e-07 28.7 2.3 1.3e-05 24.6 0.7 2.6 1 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 EKX44691.1 - 9.8e-06 25.0 0.2 3.7e-05 23.1 0.2 1.9 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.6 EKX44691.1 - 2.3e-05 24.3 1.3 0.00027 20.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_31 PF13614.6 EKX44691.1 - 2.5e-05 24.3 1.8 0.0007 19.5 1.8 2.2 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EKX44691.1 - 0.00016 21.3 0.1 0.00031 20.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EKX44691.1 - 0.0068 15.6 1.0 0.0089 15.2 0.3 1.5 2 0 0 2 2 2 1 NB-ARC domain RsgA_GTPase PF03193.16 EKX44691.1 - 0.012 15.5 0.2 0.025 14.5 0.2 1.4 1 0 0 1 1 1 0 RsgA GTPase Zn_Tnp_IS1595 PF12760.7 EKX44691.1 - 0.02 14.9 0.1 0.055 13.5 0.1 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain AAA_16 PF13191.6 EKX44691.1 - 0.03 14.7 0.1 0.053 13.9 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 EKX44691.1 - 0.037 13.0 0.4 0.056 12.4 0.4 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 EKX44691.1 - 0.047 13.6 0.1 0.081 12.8 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase NTPase_1 PF03266.15 EKX44691.1 - 0.056 13.3 0.7 0.097 12.6 0.2 1.6 2 0 0 2 2 2 0 NTPase SRP54 PF00448.22 EKX44691.1 - 0.078 12.6 0.1 7.9 6.1 0.1 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 EKX44691.1 - 0.082 12.2 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 EKX44691.1 - 0.13 12.5 0.1 0.33 11.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 EKX44691.1 - 0.22 10.7 0.2 0.35 10.0 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 CBP_BcsQ PF06564.12 EKX44691.1 - 0.29 10.6 0.8 1.4 8.3 0.8 1.9 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ PIG-X PF08320.12 EKX44694.1 - 9e-13 48.6 0.1 1.3e-12 48.1 0.1 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 Cas_DxTHG PF09455.10 EKX44695.1 - 0.11 12.1 0.4 0.18 11.3 0.4 1.3 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family GAS PF13851.6 EKX44696.1 - 8.2e-05 22.0 15.7 0.00023 20.6 9.5 2.3 1 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding MIP-T3_C PF17749.1 EKX44696.1 - 0.0031 17.5 2.8 0.0031 17.5 2.8 2.6 1 1 2 3 3 3 1 Microtubule-binding protein MIP-T3 C-terminal region Tropomyosin_1 PF12718.7 EKX44696.1 - 0.061 13.5 18.1 0.23 11.6 11.1 3.1 1 1 1 3 3 3 0 Tropomyosin like Prefoldin_2 PF01920.20 EKX44696.1 - 0.068 13.1 12.4 0.48 10.4 7.3 3.6 2 1 1 3 3 3 0 Prefoldin subunit DUF4200 PF13863.6 EKX44696.1 - 0.074 13.4 15.6 0.11 12.9 7.9 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF4200) DUF3867 PF12983.7 EKX44696.1 - 0.097 12.7 0.5 6.2 6.8 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3867) Tropomyosin PF00261.20 EKX44696.1 - 0.13 11.6 22.2 0.23 10.8 22.2 1.3 1 1 0 1 1 1 0 Tropomyosin Syntaxin-6_N PF09177.11 EKX44696.1 - 0.23 12.0 11.5 1.5 9.4 1.2 3.2 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 EKX44696.1 - 0.33 11.0 7.5 1.1 9.3 3.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 EKX44696.1 - 0.44 8.4 6.8 0.59 8.0 6.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ERM PF00769.19 EKX44696.1 - 0.46 10.2 17.9 0.88 9.3 6.9 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family TolA_bind_tri PF16331.5 EKX44696.1 - 0.5 10.5 13.8 1.8 8.7 0.4 3.6 2 1 0 3 3 3 0 TolA binding protein trimerisation CheZ PF04344.13 EKX44696.1 - 0.61 10.0 7.9 0.32 10.9 5.0 1.9 1 1 1 2 2 2 0 Chemotaxis phosphatase, CheZ THOC7 PF05615.13 EKX44696.1 - 0.83 9.9 16.0 3.6 7.9 6.5 2.4 1 1 1 2 2 2 0 Tho complex subunit 7 Spc7 PF08317.11 EKX44696.1 - 0.97 8.2 16.3 1.8 7.4 3.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 EKX44696.1 - 1.3 9.3 22.4 1.3 9.3 13.1 2.7 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Atg14 PF10186.9 EKX44696.1 - 1.7 7.7 17.3 0.93 8.5 4.5 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3450 PF11932.8 EKX44696.1 - 3 7.1 11.6 0.17 11.2 5.6 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Exonuc_VII_L PF02601.15 EKX44696.1 - 3 7.3 10.6 4.7 6.7 10.6 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit FUSC PF04632.12 EKX44696.1 - 3.3 6.1 4.2 4 5.8 4.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DivIC PF04977.15 EKX44696.1 - 3.3 7.5 10.1 3.5 7.5 1.0 3.5 2 2 1 3 3 3 0 Septum formation initiator XhlA PF10779.9 EKX44696.1 - 3.6 7.8 12.6 1.5 9.0 2.0 2.9 2 1 2 4 4 3 0 Haemolysin XhlA DUF4164 PF13747.6 EKX44696.1 - 5 7.5 15.9 4.1 7.7 8.5 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF4164) TMPIT PF07851.13 EKX44696.1 - 6.4 5.9 10.9 1.4 8.1 3.7 2.1 1 1 1 2 2 2 0 TMPIT-like protein DUF724 PF05266.14 EKX44696.1 - 7.3 6.4 16.3 6.6 6.5 10.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Seryl_tRNA_N PF02403.22 EKX44696.1 - 8 6.7 10.8 1.8 8.9 2.9 2.8 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 EKX44696.1 - 8.4 6.9 21.7 21 5.7 18.1 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region PDZ_6 PF17820.1 EKX44697.1 - 1.5e-09 37.5 0.1 3.5e-09 36.4 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX44697.1 - 8.6e-09 35.6 0.2 2.6e-08 34.1 0.2 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX44697.1 - 5.9e-05 23.3 0.1 0.00013 22.2 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Toxin_18 PF08087.11 EKX44697.1 - 1.7 8.7 6.4 0.24 11.4 2.1 1.8 2 0 0 2 2 2 0 Conotoxin O-superfamily SSF PF00474.17 EKX44698.1 - 3.7e-08 32.7 26.8 1.6e-07 30.6 25.5 2.4 1 1 0 1 1 1 1 Sodium:solute symporter family Jiraiya PF15038.6 EKX44698.1 - 0.71 9.3 7.6 23 4.4 0.0 3.1 3 0 0 3 3 3 0 Jiraiya Oxysterol_BP PF01237.18 EKX44699.1 - 4.9e-85 285.6 0.2 1.9e-82 277.1 0.2 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Acetyltransf_1 PF00583.25 EKX44700.1 - 0.00011 22.5 0.0 0.0003 21.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family SAP PF02037.27 EKX44700.1 - 0.00019 21.1 0.1 0.00056 19.6 0.1 1.8 2 0 0 2 2 2 1 SAP domain Acetyltransf_7 PF13508.7 EKX44700.1 - 0.12 12.8 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Calx-beta PF03160.14 EKX44701.1 - 7.4e-07 29.3 0.0 1.4e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Calx-beta domain TIG PF01833.24 EKX44701.1 - 4.8e-05 23.4 0.1 0.00027 21.0 0.1 2.4 1 0 0 1 1 1 1 IPT/TIG domain Seryl_tRNA_N PF02403.22 EKX44702.1 - 0.013 15.7 1.5 0.013 15.7 1.5 4.3 1 1 4 5 5 5 0 Seryl-tRNA synthetase N-terminal domain 2OG-FeII_Oxy_3 PF13640.6 EKX44704.1 - 3.3e-07 31.1 0.0 2.9e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF1424 PF07232.11 EKX44704.1 - 0.082 11.9 0.1 0.12 11.4 0.1 1.1 1 0 0 1 1 1 0 Putative rep protein (DUF1424) Asp PF00026.23 EKX44705.1 - 2.6e-33 115.8 0.0 5e-23 82.0 0.0 2.4 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EKX44705.1 - 8.9e-07 29.3 0.0 0.0003 21.1 0.0 2.4 2 0 0 2 2 2 2 Xylanase inhibitor N-terminal NPR3 PF03666.13 EKX44706.1 - 4.1e-16 58.8 7.3 3.9e-09 35.8 0.3 4.2 2 1 2 4 4 4 2 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 EKX44706.1 - 0.11 11.2 0.0 0.66 8.7 0.0 2.1 2 1 0 3 3 3 0 Nitrogen permease regulator 2 HTH_3 PF01381.22 EKX44708.1 - 0.072 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix HTH_3 PF01381.22 EKX44709.1 - 0.072 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix Sec63 PF02889.16 EKX44710.1 - 8.2e-23 80.9 0.0 1.5e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Sec63 Brl domain Rab_eff_C PF04698.12 EKX44710.1 - 0.12 10.6 0.4 0.19 10.0 0.4 1.2 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus Iron_permease PF04120.12 EKX44712.1 - 0.68 9.7 6.6 2 8.2 6.6 1.7 1 0 0 1 1 1 0 Low affinity iron permease HTH_3 PF01381.22 EKX44713.1 - 0.072 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix Sec34 PF04136.15 EKX44714.1 - 3.5e-29 101.6 2.3 5.4e-29 101.0 1.0 2.0 2 0 0 2 2 2 1 Sec34-like family DUF2120 PF09893.9 EKX44714.1 - 0.047 13.8 0.1 0.14 12.2 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) OSCP PF00213.18 EKX44714.1 - 0.047 13.8 1.8 0.16 12.0 1.8 1.9 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit Pinin_SDK_memA PF04696.13 EKX44714.1 - 0.093 12.8 15.7 0.039 14.0 11.9 2.4 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Histone PF00125.24 EKX44714.1 - 1.1 9.6 10.4 0.99 9.8 7.5 2.3 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Solute_trans_a PF03619.16 EKX44716.1 - 4.3e-62 210.0 13.1 1.7e-61 208.1 13.1 1.7 1 1 0 1 1 1 1 Organic solute transporter Ostalpha UPF0114 PF03350.16 EKX44716.1 - 1.6 9.0 7.9 0.24 11.6 2.5 2.2 1 1 1 2 2 2 0 Uncharacterized protein family, UPF0114 PDZ_6 PF17820.1 EKX44717.1 - 0.035 13.9 0.0 4.7 7.1 0.0 2.8 2 0 0 2 2 2 0 PDZ domain DUF4820 PF16091.5 EKX44717.1 - 0.14 11.5 0.0 0.43 9.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF3408 PF11888.8 EKX44718.1 - 0.015 15.5 0.7 0.024 14.8 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) NCBP3 PF10309.9 EKX44719.1 - 0.11 12.3 0.0 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 Nuclear cap-binding protein subunit 3 Tho1_MOS11_C PF18592.1 EKX44719.1 - 1.4 8.7 13.1 2.6 7.9 0.2 3.9 4 1 0 4 4 4 0 Tho1/MOS11 C-terminal domain DUF4201 PF13870.6 EKX44720.1 - 4e-46 157.0 34.1 4e-46 157.0 34.1 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF4201) IQ PF00612.27 EKX44720.1 - 0.051 13.4 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif PP2C_C PF07830.13 EKX44720.1 - 6.1 7.4 11.9 5.6 7.5 1.8 3.8 3 0 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain C2 PF00168.30 EKX44721.1 - 5.8e-10 39.4 0.0 1.1e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain CSRNP_N PF16019.5 EKX44721.1 - 4 7.3 5.6 1.7 8.5 0.1 2.1 1 1 1 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Methyltransf_21 PF05050.12 EKX44722.1 - 1.2e-06 28.6 1.0 0.00089 19.3 0.0 3.1 2 1 1 3 3 3 2 Methyltransferase FkbM domain Glycos_transf_2 PF00535.26 EKX44723.1 - 6e-22 78.3 0.0 9.1e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 EKX44723.1 - 7.2e-09 35.5 0.0 1.5e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 EKX44723.1 - 3.9e-08 33.5 0.0 1.1e-07 32.0 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 F-box PF00646.33 EKX44724.1 - 0.01 15.7 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 EKX44724.1 - 0.016 15.7 0.0 0.023 15.2 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box-like PF12937.7 EKX44724.1 - 0.068 13.1 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 F-box-like DUF1751 PF08551.10 EKX44725.1 - 5.7e-18 65.3 9.2 6.4e-18 65.2 7.9 1.8 1 1 1 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Glyco_transf_18 PF15024.6 EKX44726.1 - 1.1e-05 24.3 6.1 0.0054 15.4 0.3 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 18 DUF525 PF04379.14 EKX44727.1 - 2e-25 88.8 0.3 3.5e-21 75.2 0.1 2.4 2 0 0 2 2 2 2 ApaG domain Slp PF03843.13 EKX44727.1 - 0.17 11.3 0.1 0.28 10.6 0.1 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein Slp family MORN PF02493.20 EKX44728.1 - 5e-11 41.8 22.2 0.00024 20.8 0.1 6.2 6 0 0 6 6 6 5 MORN repeat PDZ PF00595.24 EKX44729.1 - 2.1e-10 40.8 0.0 5.2e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX44729.1 - 3e-09 37.1 0.2 7e-09 35.9 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX44729.1 - 2.2e-08 33.8 0.2 5e-08 32.7 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PCDO_beta_N PF12391.8 EKX44729.1 - 0.0048 16.5 0.1 0.017 14.7 0.0 1.9 2 0 0 2 2 2 1 Protocatechuate 3,4-dioxygenase beta subunit N terminal Methyltransf_16 PF10294.9 EKX44730.1 - 1.9e-19 70.0 0.0 2.7e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Glyco_transf_49 PF13896.6 EKX44732.1 - 2.1e-26 93.1 0.0 1e-17 64.5 0.0 2.3 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Profilin PF00235.19 EKX44733.1 - 0.00034 20.9 0.0 0.00045 20.5 0.0 1.2 1 0 0 1 1 1 1 Profilin FKBP_C PF00254.28 EKX44734.1 - 1.3e-39 134.4 0.4 4.3e-14 52.6 0.1 3.4 3 0 0 3 3 3 3 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_19 PF14559.6 EKX44734.1 - 6.5e-08 33.0 1.0 1.2e-06 28.9 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat FKBP_N_2 PF18023.1 EKX44734.1 - 5.1e-07 29.8 0.0 0.0046 17.0 0.0 2.8 2 0 0 2 2 2 2 BDBT FKBP like N-terminal TPR_1 PF00515.28 EKX44734.1 - 1.3e-06 27.9 3.4 0.028 14.2 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX44734.1 - 1.7e-06 27.7 7.9 7.5e-05 22.5 0.1 3.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX44734.1 - 1.9e-06 28.2 0.3 0.00014 22.3 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.6 EKX44734.1 - 0.00064 20.0 1.4 0.99 9.8 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX44734.1 - 0.001 19.1 1.2 0.0045 17.1 0.0 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX44734.1 - 0.0013 18.4 0.5 0.39 10.4 0.1 2.9 2 1 1 3 3 3 1 TPR repeat TPR_16 PF13432.6 EKX44734.1 - 0.0021 18.7 0.2 1.5 9.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX44734.1 - 0.011 15.9 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX44734.1 - 0.02 15.2 1.0 14 6.0 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 EKX44734.1 - 0.022 15.1 0.1 2.5 8.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EKX44734.1 - 0.03 14.4 0.2 3.4 7.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX44734.1 - 0.069 13.8 5.4 0.31 11.8 0.1 3.9 4 1 0 4 4 3 0 Tetratricopeptide repeat SLT_L PF14718.6 EKX44734.1 - 0.14 12.3 0.5 0.32 11.2 0.5 1.5 1 0 0 1 1 1 0 Soluble lytic murein transglycosylase L domain DUF547 PF04784.14 EKX44736.1 - 4.8e-07 29.8 0.0 1.1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Glutaredoxin PF00462.24 EKX44736.1 - 1e-05 25.6 0.0 2.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin DEP PF00610.21 EKX44736.1 - 0.0024 17.9 0.0 0.0091 16.0 0.0 2.0 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ADP_ribosyl_GH PF03747.14 EKX44737.1 - 2.9e-19 69.9 0.0 1.2e-10 41.6 0.0 2.2 1 1 1 2 2 2 2 ADP-ribosylglycohydrolase LRR_6 PF13516.6 EKX44738.1 - 2.7e-14 51.9 2.6 0.024 14.7 0.1 5.2 5 0 0 5 5 5 4 Leucine Rich repeat LRR_8 PF13855.6 EKX44738.1 - 0.0036 17.0 1.5 2.7 7.8 0.4 3.4 2 1 0 2 2 2 2 Leucine rich repeat D-ser_dehydrat PF14031.6 EKX44739.1 - 6.5e-18 65.2 0.0 1.1e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 EKX44739.1 - 5.1e-16 59.0 0.0 7.5e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Beta_helix PF13229.6 EKX44740.1 - 3e-05 23.9 0.0 0.0042 17.0 0.0 3.4 3 1 0 3 3 3 1 Right handed beta helix region Chlam_PMP PF02415.17 EKX44740.1 - 0.0026 18.1 9.0 6.4 7.5 0.0 5.7 5 1 0 5 5 5 2 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Stm1_N PF09598.10 EKX44740.1 - 0.15 12.9 0.3 0.29 12.0 0.3 1.4 1 0 0 1 1 1 0 Stm1 Kinesin PF00225.23 EKX44741.1 - 1.4e-81 274.1 9.1 1.1e-56 192.2 0.3 3.2 2 1 1 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 EKX44741.1 - 9.8e-16 58.0 0.0 4.7e-15 55.8 0.0 2.3 1 0 0 1 1 1 1 Microtubule binding Kinesin_assoc PF16183.5 EKX44741.1 - 5.1e-14 52.8 12.9 1.6e-13 51.2 3.8 6.2 3 2 2 5 5 5 2 Kinesin-associated FHA PF00498.26 EKX44741.1 - 4.3e-07 30.2 0.1 1.2e-06 28.7 0.1 1.9 1 0 0 1 1 1 1 FHA domain KIF1B PF12423.8 EKX44741.1 - 0.025 15.0 2.2 0.13 12.8 2.2 2.4 1 0 0 1 1 1 0 Kinesin protein 1B RVT_1 PF00078.27 EKX44744.1 - 1.8e-08 34.2 0.1 3.5e-08 33.3 0.1 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Syntaxin-6_N PF09177.11 EKX44745.1 - 0.0014 19.1 1.9 3 8.5 0.0 3.1 2 1 1 3 3 3 2 Syntaxin 6, N-terminal SNARE PF05739.19 EKX44745.1 - 0.062 13.3 0.7 0.14 12.1 0.7 1.6 1 0 0 1 1 1 0 SNARE domain Ofd1_CTDD PF10637.9 EKX44746.1 - 4.6e-44 150.7 0.0 1.6e-40 139.1 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 EKX44746.1 - 2e-19 70.0 0.0 6.2e-19 68.5 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EKX44746.1 - 5.6e-10 40.0 0.0 1.6e-09 38.5 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Chloroa_b-bind PF00504.21 EKX44747.1 - 1e-10 42.4 0.4 7.6e-06 26.5 0.0 2.3 1 1 0 2 2 2 2 Chlorophyll A-B binding protein Lamprin PF06403.11 EKX44748.1 - 0.0048 16.9 0.3 0.046 13.7 0.0 2.3 1 1 1 2 2 2 1 Lamprin LIP PF03583.14 EKX44749.1 - 0.0003 20.2 0.2 0.00041 19.8 0.2 1.1 1 0 0 1 1 1 1 Secretory lipase Apolipoprotein PF01442.18 EKX44749.1 - 0.0018 18.2 2.1 0.0025 17.7 2.1 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Nup54 PF13874.6 EKX44749.1 - 0.046 13.8 2.9 0.081 13.0 2.9 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Seryl_tRNA_N PF02403.22 EKX44749.1 - 0.21 11.8 1.7 0.36 11.1 1.7 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain T3SS_needle_E PF08988.10 EKX44749.1 - 8.5 6.6 9.1 0.26 11.4 1.5 2.1 2 1 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle Kelch_1 PF01344.25 EKX44751.1 - 6.3e-13 48.1 1.0 1.4e-05 24.6 0.0 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 EKX44751.1 - 2.4e-11 43.5 8.0 0.0046 16.9 1.5 6.0 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EKX44751.1 - 3.4e-11 42.9 5.5 0.0034 17.3 0.0 5.7 6 1 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 EKX44751.1 - 2.4e-09 36.8 1.7 0.034 14.1 0.1 5.8 6 0 0 6 6 6 2 Kelch motif Kelch_3 PF13415.6 EKX44751.1 - 1.3e-07 31.7 9.8 0.028 14.7 0.0 6.5 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_6 PF13964.6 EKX44751.1 - 1.2e-06 28.6 0.4 0.072 13.4 0.0 5.3 5 0 0 5 5 5 1 Kelch motif F-box-like PF12937.7 EKX44751.1 - 0.00019 21.3 0.1 0.00047 20.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like SDA1 PF05285.12 EKX44751.1 - 0.43 9.9 23.7 0.61 9.5 23.7 1.1 1 0 0 1 1 1 0 SDA1 Paf1 PF03985.13 EKX44751.1 - 3.2 6.7 18.1 4.5 6.2 18.1 1.1 1 0 0 1 1 1 0 Paf1 Myb_DNA-binding PF00249.31 EKX44752.1 - 5.3e-31 106.5 1.0 5.1e-17 61.8 0.1 2.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX44752.1 - 6.5e-26 90.4 0.3 1.4e-16 60.4 0.0 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EKX44752.1 - 0.0016 18.3 0.0 0.023 14.6 0.0 2.0 1 1 1 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 EKX44752.1 - 0.007 16.4 0.0 3.7 7.6 0.0 2.2 1 1 0 2 2 2 2 SLIDE Myb_DNA-bind_2 PF08914.11 EKX44752.1 - 0.018 15.2 0.5 3.8 7.8 0.0 2.9 1 1 1 2 2 2 0 Rap1 Myb domain Thioredoxin PF00085.20 EKX44753.1 - 2.3e-15 56.4 0.0 2.9e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EKX44753.1 - 1.5e-09 38.3 0.0 2.3e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EKX44753.1 - 1.6e-06 28.4 0.0 9.7e-05 22.6 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.6 EKX44753.1 - 3.6e-06 27.0 0.0 5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EKX44753.1 - 5.4e-05 23.1 0.0 9.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EKX44753.1 - 9e-05 22.2 0.1 0.00016 21.4 0.0 1.5 1 1 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.6 EKX44753.1 - 9.6e-05 22.2 0.0 0.00011 21.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.6 EKX44753.1 - 0.003 17.5 0.0 0.0034 17.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EKX44753.1 - 0.0097 15.3 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 EKX44753.1 - 0.014 15.2 0.0 0.017 14.9 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 EKX44753.1 - 0.11 12.7 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin DnaJ PF00226.31 EKX44754.1 - 1e-26 92.8 2.3 1.1e-26 92.7 2.3 1.0 1 0 0 1 1 1 1 DnaJ domain FA_hydroxylase PF04116.13 EKX44755.1 - 3.3e-07 30.7 9.9 3.6e-07 30.6 8.6 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Pcc1 PF09341.10 EKX44756.1 - 2e-21 75.9 0.2 2.3e-21 75.7 0.2 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 Lig_chan PF00060.26 EKX44757.1 - 4e-09 36.5 0.0 9.7e-09 35.2 0.0 1.7 1 1 0 1 1 1 1 Ligand-gated ion channel DNA_pol_phi PF04931.13 EKX44757.1 - 0.035 12.2 0.3 0.051 11.7 0.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi U-box PF04564.15 EKX44759.1 - 1.9e-18 66.4 0.0 2.2e-18 66.2 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX44759.1 - 0.00054 19.7 0.0 0.00079 19.2 0.0 1.3 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EKX44759.1 - 0.0089 16.0 0.0 0.012 15.6 0.0 1.5 1 1 0 1 1 1 1 RING-type zinc-finger zf-NOSIP PF15906.5 EKX44759.1 - 0.013 15.7 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Pkinase_Tyr PF07714.17 EKX44760.1 - 2e-40 138.7 0.0 2.2e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX44760.1 - 5e-16 58.9 0.0 6.1e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Prok-JAB PF14464.6 EKX44761.1 - 1.1e-05 25.2 1.8 2 8.2 0.3 3.1 3 0 0 3 3 3 3 Prokaryotic homologs of the JAB domain DUF3216 PF11505.8 EKX44761.1 - 3e-05 24.1 0.0 8.5 6.7 0.0 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF3216) Gastrin PF00918.17 EKX44761.1 - 0.00014 22.8 3.9 2.1 9.4 0.1 3.1 1 1 2 3 3 3 2 Gastrin/cholecystokinin family Anti-adapt_IraP PF10796.9 EKX44761.1 - 0.0014 19.1 8.2 16 6.2 0.2 5.1 3 3 1 4 4 4 0 Sigma-S stabilisation anti-adaptor protein DUF3209 PF11483.8 EKX44761.1 - 0.0031 18.0 0.7 5.6 7.4 0.1 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3209) DUF4747 PF15931.5 EKX44761.1 - 0.0074 16.0 0.0 15 5.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4747) Exotox-A_target PF09102.10 EKX44761.1 - 0.011 15.7 2.1 17 5.4 0.0 3.3 3 0 0 3 3 3 0 Exotoxin A, targeting INSC_LBD PF16748.5 EKX44761.1 - 0.017 14.5 3.4 23 4.5 0.1 3.4 3 0 0 3 3 3 0 Inscuteable LGN-binding domain PsaX PF08078.12 EKX44761.1 - 0.025 14.5 0.1 10 6.2 0.0 2.4 2 0 0 2 2 2 0 PsaX family PUB_1 PF18486.1 EKX44761.1 - 0.025 14.4 0.1 76 3.3 0.0 3.5 3 0 0 3 3 3 0 PNGase/UBA- or UBX-containing domain D5_N PF08706.11 EKX44761.1 - 0.039 14.2 0.4 0.97 9.7 0.4 2.7 1 1 0 1 1 1 0 D5 N terminal like Glyco_hydro_125 PF06824.11 EKX44761.1 - 0.066 12.1 2.9 0.29 9.9 0.9 2.2 1 1 1 2 2 2 0 Metal-independent alpha-mannosidase (GH125) DUF4795 PF16043.5 EKX44761.1 - 0.083 12.5 2.1 22 4.6 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) RPA_interact_C PF14768.6 EKX44761.1 - 0.1 13.2 4.0 58 4.4 0.1 3.2 3 0 0 3 3 3 0 Replication protein A interacting C-terminal ERp29 PF07749.12 EKX44761.1 - 0.1 13.5 1.4 33 5.5 0.1 3.0 3 0 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain PARP_regulatory PF01358.18 EKX44761.1 - 0.17 10.8 0.0 13 4.6 0.0 2.1 1 1 1 2 2 2 0 Poly A polymerase regulatory subunit Arteri_nucleo PF01481.16 EKX44761.1 - 0.2 11.9 1.7 97 3.3 0.1 3.2 3 0 0 3 3 3 0 Arterivirus nucleocapsid protein GldM_N PF12081.8 EKX44761.1 - 0.28 11.3 3.4 29 4.7 0.1 3.0 3 0 0 3 3 3 0 GldM N-terminal domain Hira PF07569.11 EKX44761.1 - 0.32 10.7 6.1 4.4 7.0 0.3 2.8 3 0 0 3 3 3 0 TUP1-like enhancer of split Cob_adeno_trans PF01923.18 EKX44761.1 - 0.66 10.1 6.4 7.3 6.7 0.5 2.9 1 1 2 3 3 3 0 Cobalamin adenosyltransferase RVT_1 PF00078.27 EKX44762.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) TPR_12 PF13424.6 EKX44763.1 - 4e-08 33.4 3.9 0.004 17.4 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX44763.1 - 0.064 13.1 0.9 0.32 10.9 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat CTD_bind PF04818.13 EKX44765.1 - 3.3e-06 27.8 0.1 9.3e-06 26.4 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF4667 PF15700.5 EKX44766.1 - 6.1e-06 26.5 4.7 1.1e-05 25.7 4.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) Apt1 PF10351.9 EKX44766.1 - 0.25 10.2 5.3 0.085 11.7 0.6 1.9 2 0 0 2 2 2 0 Golgi-body localisation protein domain EBP50_C PF09007.11 EKX44766.1 - 0.31 12.0 7.3 0.49 11.4 2.4 2.3 2 0 0 2 2 2 0 EBP50, C-terminal Cyclin PF08613.11 EKX44766.1 - 1.1 9.6 6.6 7.1 7.0 2.7 2.2 2 0 0 2 2 2 0 Cyclin CCDC24 PF15669.5 EKX44766.1 - 7.5 6.4 10.3 0.3 10.9 3.5 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family SR-25 PF10500.9 EKX44766.1 - 8.4 5.9 36.7 0.23 11.1 24.4 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF5082 PF16888.5 EKX44767.1 - 0.02 15.2 1.7 0.36 11.1 1.5 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Spc7 PF08317.11 EKX44767.1 - 0.1 11.4 0.8 0.1 11.5 0.8 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein CAMSAP_CC1 PF17095.5 EKX44767.1 - 0.27 11.1 14.7 4.5 7.2 3.0 2.9 1 1 3 4 4 4 0 Spectrin-binding region of Ca2+-Calmodulin ELH PF02323.15 EKX44767.1 - 0.47 9.8 7.4 1.4 8.2 1.5 1.8 1 1 1 2 2 2 0 Egg-laying hormone precursor M PF02370.16 EKX44767.1 - 6.1 7.8 7.0 38 5.3 0.5 2.6 1 1 1 3 3 3 0 M protein repeat DUF3152 PF11350.8 EKX44768.1 - 0.067 12.9 0.3 0.15 11.8 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3152) DNA_meth_N PF18284.1 EKX44771.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 DNA methylase N-terminal domain TPR_12 PF13424.6 EKX44772.1 - 0.0026 18.0 3.4 0.0096 16.2 1.4 2.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX44772.1 - 0.013 14.9 2.5 0.019 14.4 2.5 1.2 1 0 0 1 1 1 0 MalT-like TPR region TPR_8 PF13181.6 EKX44772.1 - 0.05 13.8 0.5 0.24 11.7 0.1 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EKX44772.1 - 0.37 11.0 0.2 0.37 11.0 0.2 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat PDEase_I PF00233.19 EKX44773.1 - 2.2e-80 269.8 0.1 2.7e-80 269.5 0.1 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ank_2 PF12796.7 EKX44774.1 - 5.8e-08 33.2 0.1 1.2e-07 32.2 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) PDZ_2 PF13180.6 EKX44774.1 - 2.7e-07 30.8 0.0 8.5e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX44774.1 - 4.9e-06 26.8 0.1 1.3e-05 25.4 0.1 1.6 1 0 0 1 1 1 1 PDZ domain Ank_5 PF13857.6 EKX44774.1 - 8.2e-06 26.0 0.0 3.2e-05 24.1 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) PDZ_6 PF17820.1 EKX44774.1 - 1.8e-05 24.5 1.3 3.1e-05 23.7 0.2 2.1 2 0 0 2 2 2 1 PDZ domain Ank PF00023.30 EKX44774.1 - 7.7e-05 23.0 0.0 0.00029 21.1 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 EKX44774.1 - 0.00043 20.8 0.0 0.001 19.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX44774.1 - 0.0014 18.9 0.0 0.0079 16.6 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat SH3_2 PF07653.17 EKX44774.1 - 0.034 13.8 0.0 0.34 10.6 0.0 2.3 2 0 0 2 2 2 0 Variant SH3 domain HATPase_c_3 PF13589.6 EKX44775.1 - 1.2e-10 41.4 0.1 3.2e-10 40.0 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Rad60-SLD PF11976.8 EKX44776.1 - 2.3e-27 94.6 0.4 2.7e-27 94.4 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EKX44776.1 - 8.5e-16 57.5 0.2 9.7e-16 57.3 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin family RRM_1 PF00076.22 EKX44777.1 - 6.9e-11 41.8 0.0 1.2e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EKX44777.1 - 0.04 14.0 0.0 0.092 12.9 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif 60KD_IMP PF02096.20 EKX44778.1 - 2.8e-44 150.9 0.1 5.9e-44 149.9 0.1 1.5 1 0 0 1 1 1 1 60Kd inner membrane protein SMC_N PF02463.19 EKX44780.1 - 3.9e-34 118.0 3.4 1.2e-33 116.5 3.4 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EKX44780.1 - 7.7e-17 62.5 2.4 9.5e-17 62.2 2.4 1.1 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EKX44780.1 - 4.6e-09 36.5 6.2 5.9e-09 36.1 6.2 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EKX44780.1 - 3.8e-05 23.6 0.0 5.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EKX44780.1 - 0.019 14.7 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EKX44780.1 - 0.045 14.3 1.6 0.47 11.0 1.6 2.4 1 1 0 1 1 1 0 ABC transporter Peptidase_S24 PF00717.23 EKX44780.1 - 0.059 13.3 0.3 0.23 11.4 0.2 2.0 2 0 0 2 2 2 0 Peptidase S24-like JMY PF15871.5 EKX44780.1 - 0.061 12.6 7.8 0.08 12.2 7.8 1.1 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein DUF87 PF01935.17 EKX44780.1 - 0.26 11.4 8.1 1.9 8.6 0.0 3.0 1 1 1 2 2 2 0 Helicase HerA, central domain Transket_pyr PF02779.24 EKX44782.1 - 2e-43 148.1 0.0 2.7e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EKX44782.1 - 3.1e-32 111.1 0.0 5.9e-32 110.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 EKX44782.1 - 0.17 12.2 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II MCPsignal PF00015.21 EKX44783.1 - 0.0043 16.9 0.4 0.0069 16.2 0.4 1.3 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain FlgM PF04316.13 EKX44783.1 - 0.058 13.8 0.2 17 5.9 0.1 2.5 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM Fz PF01392.22 EKX44784.1 - 8e-06 26.4 3.8 1.4e-05 25.7 3.8 1.6 1 0 0 1 1 1 1 Fz domain TPR_1 PF00515.28 EKX44786.1 - 2.8e-08 33.2 3.4 0.073 12.9 0.1 7.7 10 0 0 10 10 10 2 Tetratricopeptide repeat SNAP PF14938.6 EKX44786.1 - 1.7e-07 30.9 5.7 0.3 10.5 1.5 4.3 1 1 2 4 4 4 3 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 EKX44786.1 - 3.3e-06 26.8 2.2 9.8 6.6 0.0 8.1 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX44786.1 - 7.6e-05 22.9 7.3 9.3 6.6 0.0 7.3 5 3 2 8 8 8 3 Tetratricopeptide repeat ABC2_membrane_3 PF12698.7 EKX44786.1 - 0.14 11.2 0.2 0.19 10.8 0.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein TPR_8 PF13181.6 EKX44786.1 - 0.15 12.3 2.6 5.1 7.6 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat THF_DHG_CYH PF00763.23 EKX44787.1 - 1.8e-14 54.0 0.0 3.4e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 EKX44787.1 - 7e-13 48.2 0.1 1.9e-11 43.5 0.1 2.7 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MeaB PF03308.16 EKX44788.1 - 4.7e-75 252.0 4.1 6.7e-74 248.2 2.4 2.3 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 EKX44788.1 - 0.00074 19.2 2.2 0.0078 15.8 1.6 2.7 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EKX44788.1 - 0.028 14.9 0.0 0.074 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EKX44788.1 - 0.15 12.5 0.0 0.36 11.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter APG6_N PF17675.1 EKX44789.1 - 6.4 7.3 17.8 30 5.2 15.8 3.1 2 1 0 2 2 2 0 Apg6 coiled-coil region BTB PF00651.31 EKX44790.1 - 1.6e-11 44.4 0.1 3e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 EKX44790.1 - 8.3e-09 35.5 4.4 3.4e-06 27.1 0.6 3.7 3 2 0 3 3 3 2 BTB And C-terminal Kelch NIR_SIR PF01077.22 EKX44790.1 - 0.13 11.8 0.2 0.25 10.8 0.2 1.4 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain Bac_rhodopsin PF01036.18 EKX44791.1 - 8.3e-45 153.1 19.7 1.1e-44 152.7 19.7 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein GWT1 PF06423.12 EKX44791.1 - 3.8 7.6 5.7 8.2 6.5 1.0 2.5 1 1 1 2 2 2 0 GWT1 FAD_binding_1 PF00667.20 EKX44792.1 - 3.3e-49 167.4 0.1 5.8e-49 166.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EKX44792.1 - 6.2e-28 97.8 0.2 1.3e-27 96.8 0.2 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EKX44792.1 - 1.3e-14 54.8 0.1 4.2e-14 53.1 0.1 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EKX44792.1 - 0.05 13.8 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 Flavodoxin domain V-ATPase_C PF03223.15 EKX44793.1 - 4e-81 273.3 0.2 4.7e-81 273.0 0.2 1.1 1 0 0 1 1 1 1 V-ATPase subunit C MP PF01107.18 EKX44793.1 - 0.024 14.2 0.1 0.79 9.3 0.0 2.2 2 0 0 2 2 2 0 Viral movement protein (MP) cobW PF02492.19 EKX44794.1 - 8.4e-54 181.8 2.8 1.3e-53 181.2 2.8 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EKX44794.1 - 4.8e-21 74.5 0.0 9.5e-21 73.5 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MeaB PF03308.16 EKX44794.1 - 3.4e-05 23.0 0.1 0.023 13.7 0.0 2.6 2 1 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 EKX44794.1 - 0.00061 19.4 1.4 0.059 12.9 0.8 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain T2SSE PF00437.20 EKX44794.1 - 0.001 18.2 1.5 0.003 16.7 0.0 2.2 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_16 PF13191.6 EKX44794.1 - 0.0012 19.3 0.1 0.015 15.7 0.0 2.5 2 2 0 2 2 2 1 AAA ATPase domain MMR_HSR1_Xtn PF16897.5 EKX44794.1 - 0.0023 17.9 0.9 0.026 14.5 0.1 2.4 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain AAA_33 PF13671.6 EKX44794.1 - 0.0024 18.1 0.9 0.027 14.6 0.1 2.9 2 2 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EKX44794.1 - 0.0099 15.8 0.0 0.95 9.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase MobB PF03205.14 EKX44794.1 - 0.021 14.7 0.1 0.075 12.9 0.0 2.0 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 EKX44794.1 - 0.033 14.8 0.5 0.18 12.4 0.5 2.4 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EKX44794.1 - 0.033 13.9 0.0 0.077 12.7 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 EKX44794.1 - 0.034 14.0 0.0 0.059 13.3 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EKX44794.1 - 0.04 14.2 0.2 0.55 10.5 0.1 2.7 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 EKX44794.1 - 0.058 13.4 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 EKX44794.1 - 0.078 13.4 0.3 4.2 7.8 0.0 3.1 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EKX44794.1 - 0.088 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EKX44794.1 - 0.15 11.9 0.1 0.35 10.6 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TUDOR PF00567.24 EKX44796.1 - 7e-08 32.5 0.0 2e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 EKX44796.1 - 4.1e-06 26.3 0.1 4.1e-06 26.3 0.1 2.0 1 1 1 2 2 2 1 Survival motor neuron protein (SMN) Big_3 PF07523.12 EKX44796.1 - 0.015 15.6 1.1 4.5 7.6 0.2 2.6 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) Agenet PF05641.12 EKX44796.1 - 0.021 15.3 0.0 0.054 14.0 0.0 1.8 1 0 0 1 1 1 0 Agenet domain DUF2730 PF10805.8 EKX44796.1 - 0.063 13.4 0.6 0.063 13.4 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) WW PF00397.26 EKX44797.1 - 8.6e-10 38.5 13.1 3.8e-05 23.7 4.3 3.0 3 0 0 3 3 3 2 WW domain DUF1794 PF08768.11 EKX44798.1 - 7.6e-05 22.7 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) PHD_Oberon PF07227.11 EKX44798.1 - 0.07 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein AAA_34 PF13872.6 EKX44799.1 - 6.4e-116 386.5 0.0 1.4e-115 385.4 0.0 1.6 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 EKX44799.1 - 2e-93 313.0 0.0 3.1e-93 312.4 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue DUF4336 PF14234.6 EKX44800.1 - 3.9e-109 364.7 0.0 4.6e-109 364.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4336) IBR PF01485.21 EKX44801.1 - 0.0079 16.4 5.8 0.0079 16.4 5.8 3.7 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain Ras PF00071.22 EKX44802.1 - 1.3e-60 203.7 0.0 1.5e-60 203.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EKX44802.1 - 1.1e-33 116.1 0.0 1.9e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EKX44802.1 - 7.7e-14 51.5 0.0 9.4e-14 51.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EKX44802.1 - 2.8e-05 23.8 0.0 0.00074 19.1 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EKX44802.1 - 0.00016 21.7 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EKX44802.1 - 0.00026 20.4 0.0 0.00031 20.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EKX44802.1 - 0.0012 18.8 0.1 1.3 8.9 0.0 2.5 1 1 2 3 3 3 2 RsgA GTPase AAA_22 PF13401.6 EKX44802.1 - 0.048 13.9 0.0 0.096 13.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 EKX44802.1 - 0.053 13.3 0.0 3.8 7.2 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 EKX44802.1 - 0.054 13.0 0.0 0.13 11.8 0.0 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region TetR_C_16 PF17920.1 EKX44802.1 - 0.083 13.1 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain AAA_16 PF13191.6 EKX44802.1 - 0.088 13.2 0.0 0.12 12.8 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 EKX44802.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF2610 PF11020.8 EKX44802.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2610) RCC1 PF00415.18 EKX44803.1 - 2e-31 108.3 25.8 4.3e-10 40.1 0.5 6.0 5 1 1 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX44803.1 - 1.7e-16 59.5 23.6 0.00058 19.6 0.1 5.4 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat Kelch_4 PF13418.6 EKX44805.1 - 2.9e-12 46.4 0.9 0.034 14.1 0.0 5.2 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EKX44805.1 - 1.4e-08 34.5 0.0 0.6 10.2 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 EKX44805.1 - 0.00021 21.5 5.1 0.4 11.0 0.1 4.9 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 EKX44805.1 - 0.00095 18.7 0.0 0.76 9.4 0.0 4.0 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 EKX44805.1 - 0.022 14.7 0.1 1.6 8.9 0.1 3.3 3 0 0 3 3 3 0 Kelch motif G_path_suppress PF15991.5 EKX44805.1 - 1.6 8.8 16.0 2.6 8.1 16.0 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor FXMR_C2 PF16098.5 EKX44805.1 - 2.2 8.8 8.4 4.6 7.8 8.4 1.5 1 0 0 1 1 1 0 Fragile X-related mental retardation protein C-terminal region 2 DUF2645 PF10840.8 EKX44806.1 - 0.65 10.7 4.1 0.44 11.2 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2645) 60KD_IMP PF02096.20 EKX44806.1 - 2 8.3 5.9 0.98 9.3 3.0 2.0 2 1 0 2 2 2 0 60Kd inner membrane protein PqiA PF04403.13 EKX44807.1 - 3.7e-07 30.1 13.6 2.7e-05 24.0 1.4 3.3 2 1 0 2 2 2 2 Paraquat-inducible protein A HCV_NS4a PF01006.20 EKX44807.1 - 0.023 14.5 0.3 0.023 14.5 0.3 3.0 3 0 0 3 3 3 0 Hepatitis C virus non-structural protein NS4a NPV_P10 PF05531.12 EKX44808.1 - 0.046 14.2 2.2 0.096 13.2 2.2 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein GAS PF13851.6 EKX44808.1 - 0.072 12.4 0.2 0.072 12.4 0.2 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CCDC53 PF10152.9 EKX44808.1 - 3 8.2 6.3 0.42 11.0 0.7 2.4 2 1 1 3 3 3 0 Subunit CCDC53 of WASH complex Mito_carr PF00153.27 EKX44809.1 - 3e-50 168.1 0.1 9.7e-17 60.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HGTP_anticodon PF03129.20 EKX44810.1 - 2.3e-22 78.9 1.1 3.9e-22 78.2 0.1 2.0 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EKX44810.1 - 2e-05 24.7 0.0 9.1e-05 22.5 0.0 2.1 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) GOLD_2 PF13897.6 EKX44811.1 - 0.11 12.9 0.0 0.11 12.9 0.0 6.3 2 2 1 3 3 3 0 Golgi-dynamics membrane-trafficking TPK_catalytic PF04263.16 EKX44812.1 - 5.8e-35 119.9 0.1 8.2e-35 119.5 0.1 1.1 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 EKX44812.1 - 8.6e-19 67.0 0.1 1.3e-18 66.5 0.1 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain CDC45 PF02724.14 EKX44814.1 - 0.99 7.6 3.5 1.5 7.0 3.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Myb_DNA-binding PF00249.31 EKX44815.1 - 8.7e-06 25.8 0.2 4.1e-05 23.7 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX44815.1 - 1e-05 25.7 0.7 5.5e-05 23.3 0.2 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Cytochrome_C7 PF14522.6 EKX44815.1 - 0.043 13.8 13.3 4.3 7.4 12.8 3.0 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c Zn_ribbon_SprT PF17283.2 EKX44815.1 - 0.11 12.5 1.8 0.3 11.0 1.8 1.8 1 0 0 1 1 1 0 SprT-like zinc ribbon domain Cytochrom_c3_2 PF14537.6 EKX44815.1 - 0.42 11.1 12.7 0.98 9.9 5.7 2.8 1 1 2 3 3 3 0 Cytochrome c3 zf-C2HE PF16278.5 EKX44815.1 - 1 9.8 3.9 3 8.3 0.0 2.9 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger HNH PF01844.23 EKX44815.1 - 4.4 7.5 17.4 50 4.2 0.1 4.5 3 1 0 3 3 3 0 HNH endonuclease CCP_MauG PF03150.14 EKX44815.1 - 4.7 7.8 7.8 29 5.3 3.2 3.4 1 1 1 2 2 2 0 Di-haem cytochrome c peroxidase MCR PF18509.1 EKX44815.1 - 7.3 6.3 14.5 0.27 10.9 1.0 3.3 3 0 0 3 3 3 0 Magnetochrome domain Cys_Met_Meta_PP PF01053.20 EKX44816.1 - 5.5e-110 367.5 0.2 7e-110 367.1 0.2 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EKX44816.1 - 5.6e-11 42.0 0.1 7.8e-11 41.5 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EKX44816.1 - 2.6e-05 23.6 0.0 4.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II GDC-P PF02347.16 EKX44816.1 - 5.9e-05 22.1 0.1 8.3e-05 21.6 0.1 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.11 EKX44816.1 - 0.00033 19.3 0.0 0.0011 17.5 0.1 1.7 1 1 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.17 EKX44816.1 - 0.011 15.0 0.3 0.02 14.2 0.1 1.4 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family cNMP_binding PF00027.29 EKX44817.1 - 2.5e-05 24.3 0.2 0.00035 20.6 0.2 2.3 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain MFS_1 PF07690.16 EKX44818.1 - 7.7e-21 74.4 16.0 1e-20 74.0 16.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OTU PF02338.19 EKX44819.1 - 0.0015 19.0 0.0 0.0025 18.3 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease NAGLU_C PF12972.7 EKX44819.1 - 0.15 11.6 0.0 0.22 11.0 0.0 1.1 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain EF-hand_1 PF00036.32 EKX44821.1 - 2e-05 23.8 1.0 0.0024 17.3 0.3 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX44821.1 - 7.8e-05 23.1 1.0 0.00024 21.5 1.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EKX44821.1 - 0.00072 19.4 2.7 0.002 18.0 1.4 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX44821.1 - 0.014 14.9 1.4 0.031 13.8 0.4 2.1 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 EKX44821.1 - 0.045 13.7 1.2 0.25 11.4 0.3 2.3 2 0 0 2 2 2 0 EF-hand domain ANAPC4_WD40 PF12894.7 EKX44822.1 - 0.018 15.3 0.3 1.7 9.0 0.0 3.7 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain FAST_1 PF06743.15 EKX44823.1 - 0.0091 15.9 1.4 0.1 12.5 0.0 3.1 3 0 0 3 3 3 1 FAST kinase-like protein, subdomain 1 DUF4390 PF14334.6 EKX44823.1 - 0.034 13.6 0.0 0.12 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4390) DUF4423 PF14394.6 EKX44824.1 - 0.0048 16.6 0.2 0.01 15.5 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4423) EF-hand_5 PF13202.6 EKX44824.1 - 0.064 12.8 0.5 0.75 9.4 0.1 2.7 2 0 0 2 2 2 0 EF hand EF-hand_1 PF00036.32 EKX44824.1 - 0.089 12.4 0.1 0.83 9.3 0.1 2.4 2 0 0 2 2 2 0 EF hand PY_rept_46 PF09689.10 EKX44825.1 - 0.19 12.3 0.3 0.19 12.3 0.3 2.3 2 0 0 2 2 2 0 Plasmodium yoelii repeat (PY_rept_46) DUF4923 PF16270.5 EKX44826.1 - 0.053 13.3 0.3 0.088 12.6 0.3 1.4 1 0 0 1 1 1 0 Lipocalin-like domain (DUF4923) Bac_rhodopsin PF01036.18 EKX44827.1 - 3.7e-37 128.1 20.0 4.5e-37 127.8 20.0 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Nucleos_tra2_C PF07662.13 EKX44827.1 - 0.2 11.5 11.0 0.075 12.9 4.4 2.2 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter C-terminus DUF4131 PF13567.6 EKX44827.1 - 3.5 7.3 12.0 3.3 7.3 3.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4191 PF13829.6 EKX44827.1 - 4 6.7 10.8 0.3 10.4 3.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Amidohydro_1 PF01979.20 EKX44828.1 - 2.3e-44 152.1 0.0 2.7e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EKX44828.1 - 0.00024 20.7 0.0 0.41 10.1 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 EKX44828.1 - 0.22 10.8 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 Adenosine/AMP deaminase UCH PF00443.29 EKX44829.1 - 1.6e-32 113.0 2.0 2.7e-19 69.7 0.1 2.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EKX44829.1 - 1.4e-09 38.0 2.2 9.5e-05 22.1 0.0 3.4 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EKX44830.1 - 7.7e-100 326.7 12.0 1.2e-32 111.4 0.5 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 EKX44830.1 - 2.3e-48 161.9 13.9 1.4e-15 56.9 0.7 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EKX44830.1 - 1.2e-15 57.7 5.9 0.0015 19.0 0.1 4.5 3 3 0 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 EKX44830.1 - 2.7e-12 46.4 1.5 0.019 14.8 0.1 3.2 3 0 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EKX44830.1 - 7.7e-11 42.1 1.1 0.093 12.8 0.0 3.9 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EKX44830.1 - 9.9e-11 41.9 3.5 0.048 14.0 0.1 3.1 3 0 0 3 3 3 3 Ubiquitin-like domain DUF2407 PF10302.9 EKX44830.1 - 8.9e-10 39.1 0.3 0.21 12.2 0.0 3.2 1 1 1 3 3 3 3 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EKX44830.1 - 1.5e-05 24.9 0.2 3.7 7.4 0.0 3.2 1 1 2 3 3 3 3 Silencing defective 2 N-terminal ubiquitin domain RelB PF04221.12 EKX44830.1 - 2.8e-05 24.0 0.0 6.5 6.8 0.0 3.2 3 0 0 3 3 3 3 RelB antitoxin ACT_5 PF13710.6 EKX44830.1 - 6.7e-05 22.6 2.3 4.9 7.1 0.0 3.3 3 0 0 3 3 3 3 ACT domain Methyltrans_RNA PF04452.14 EKX44830.1 - 0.00045 19.6 0.1 0.95 8.7 0.0 2.3 2 0 0 2 2 2 2 RNA methyltransferase UN_NPL4 PF11543.8 EKX44830.1 - 0.00064 20.2 0.4 21 5.7 0.0 3.3 3 0 0 3 3 3 0 Nuclear pore localisation protein NPL4 Ubiquitin_4 PF18036.1 EKX44830.1 - 0.00067 19.7 16.1 26 4.9 0.0 5.9 6 0 0 6 6 6 0 Ubiquitin-like domain DUF2870 PF11069.8 EKX44830.1 - 0.0012 19.2 0.0 33 4.9 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) DUF3861 PF12977.7 EKX44830.1 - 0.0016 18.6 0.8 23 5.2 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) YcgR_2 PF12945.7 EKX44830.1 - 0.0033 17.5 2.5 22 5.3 0.1 3.3 3 0 0 3 3 3 0 Flagellar protein YcgR DUF969 PF06149.12 EKX44830.1 - 0.0033 16.9 0.0 11 5.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF969) UDP-g_GGTase PF06427.11 EKX44830.1 - 0.0054 16.8 1.6 6 7.0 0.0 3.1 3 0 0 3 3 3 2 UDP-glucose:Glycoprotein Glucosyltransferase Raf1_HTH PF18579.1 EKX44830.1 - 0.0092 15.7 0.0 46 3.8 0.0 3.2 3 0 0 3 3 3 0 Rubisco accumulation factor 1 helix turn helix domain DUF3333 PF11812.8 EKX44830.1 - 0.022 15.0 3.3 31 4.7 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3333) Big_7 PF17957.1 EKX44830.1 - 0.038 14.8 0.0 1.1e+02 3.6 0.0 3.1 3 0 0 3 3 3 0 Bacterial Ig domain DUF3969 PF13108.6 EKX44830.1 - 0.043 13.8 0.2 73 3.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3969) Tash_PEST PF07708.11 EKX44830.1 - 0.14 12.4 18.4 4.5 7.6 1.4 3.3 3 0 0 3 3 3 0 Tash protein PEST motif Myosin_N PF02736.19 EKX44830.1 - 0.3 10.9 3.4 76 3.3 0.0 4.2 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain DMA PF03474.14 EKX44830.1 - 0.44 10.2 1.7 1.1e+02 2.5 0.0 3.2 3 0 0 3 3 3 0 DMRTA motif Ribosomal_S4e PF00900.20 EKX44830.1 - 3.8 7.5 6.3 76 3.3 0.2 3.8 4 2 0 4 4 3 0 Ribosomal family S4e PI3K_p85B PF02192.16 EKX44830.1 - 5 6.9 5.6 1e+02 2.7 0.1 3.2 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain Epimerase PF01370.21 EKX44831.1 - 2.1e-13 50.3 0.0 3.4e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EKX44831.1 - 2.6e-10 39.9 0.2 5.6e-05 22.4 0.2 2.5 2 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EKX44831.1 - 6.1e-10 39.3 0.0 9.4e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EKX44831.1 - 1.1e-08 34.5 0.0 1.4e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 EKX44831.1 - 2.2e-05 24.1 0.0 3.6e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 EKX44831.1 - 0.00014 21.4 0.1 0.00028 20.4 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 EKX44831.1 - 0.00015 21.3 0.0 0.00025 20.6 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EKX44831.1 - 0.00017 20.8 0.0 0.00027 20.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 EKX44831.1 - 0.0014 18.6 0.0 0.0025 17.7 0.0 1.4 1 0 0 1 1 1 1 KR domain DapB_N PF01113.20 EKX44831.1 - 0.067 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Fe-S_biosyn PF01521.20 EKX44833.1 - 1.6e-14 54.0 0.0 2.2e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis RWP-RK PF02042.15 EKX44835.1 - 1.9e-15 56.6 0.2 3e-15 55.9 0.2 1.3 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX44836.1 - 2.5e-15 56.1 0.2 4e-15 55.5 0.2 1.3 1 0 0 1 1 1 1 RWP-RK domain PTPRCAP PF15713.5 EKX44836.1 - 0.014 15.7 6.1 0.018 15.3 6.1 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated FAM176 PF14851.6 EKX44836.1 - 0.06 13.0 1.1 0.081 12.6 1.1 1.1 1 0 0 1 1 1 0 FAM176 family BT1 PF03092.16 EKX44836.1 - 0.25 9.5 0.8 0.29 9.3 0.8 1.1 1 0 0 1 1 1 0 BT1 family RWP-RK PF02042.15 EKX44837.1 - 1.7e-15 56.7 0.2 2.5e-15 56.2 0.2 1.2 1 0 0 1 1 1 1 RWP-RK domain AI-2E_transport PF01594.16 EKX44838.1 - 2.3e-05 23.7 13.7 2.7e-05 23.5 13.7 1.2 1 0 0 1 1 1 1 AI-2E family transporter Polyketide_cyc2 PF10604.9 EKX44840.1 - 3.8e-42 143.9 1.2 1.3e-12 48.2 0.0 3.2 3 0 0 3 3 3 3 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EKX44840.1 - 2e-35 121.8 0.0 4.9e-10 39.7 0.0 3.2 3 0 0 3 3 3 3 Polyketide cyclase / dehydrase and lipid transport DAHP_synth_1 PF00793.20 EKX44840.1 - 0.05 12.5 0.1 19 4.0 0.0 3.0 3 0 0 3 3 3 0 DAHP synthetase I family DUF5371 PF17341.2 EKX44840.1 - 0.1 12.8 2.4 15 5.8 0.2 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5371) DUF3284 PF11687.8 EKX44840.1 - 0.14 12.0 0.0 1.4e+02 2.4 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3284) CCDC-167 PF15188.6 EKX44840.1 - 1.7 9.1 4.4 32 4.9 0.3 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Phage_portal_2 PF05136.13 EKX44840.1 - 4.2 6.4 7.1 13 4.8 0.7 2.2 2 0 0 2 2 2 0 Phage portal protein, lambda family Lipase_GDSL_2 PF13472.6 EKX44841.1 - 4.3e-07 30.5 0.0 2.5e-05 24.7 0.0 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EKX44841.1 - 0.014 15.4 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase PseudoU_synth_2 PF00849.22 EKX44842.1 - 2.4e-17 63.5 0.0 6.9e-17 62.0 0.0 1.7 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 EKX44842.1 - 1.3e-06 28.0 0.1 9.4e-06 25.3 0.0 2.4 2 0 0 2 2 2 1 S4 domain S4_2 PF13275.6 EKX44842.1 - 0.033 14.0 0.6 0.53 10.1 0.0 2.4 2 0 0 2 2 2 0 S4 domain Fe_hyd_SSU PF02256.17 EKX44843.1 - 0.62 10.2 0.1 0.62 10.2 0.1 3.1 3 0 0 3 3 3 0 Iron hydrogenase small subunit Beta_helix PF13229.6 EKX44844.1 - 0.0012 18.8 4.7 0.0052 16.7 4.7 2.0 1 1 0 1 1 1 1 Right handed beta helix region TPR_2 PF07719.17 EKX44845.1 - 4.2e-40 132.6 11.9 1.2e-05 25.0 0.3 10.5 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_1 PF00515.28 EKX44845.1 - 1.3e-39 132.4 16.5 9.9e-07 28.3 0.9 11.9 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_12 PF13424.6 EKX44845.1 - 2.2e-24 85.5 2.5 6.7e-05 23.1 0.0 7.1 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 EKX44845.1 - 6.7e-24 84.3 0.0 6.1e-07 30.0 0.0 6.7 7 1 1 8 8 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 EKX44845.1 - 7.1e-23 78.9 18.1 0.0012 18.9 0.2 9.3 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_17 PF13431.6 EKX44845.1 - 1.1e-20 72.4 7.6 0.00017 21.7 0.2 8.8 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 EKX44845.1 - 9.6e-18 63.6 4.4 0.00021 20.9 0.0 9.4 8 3 3 11 11 10 4 TPR repeat TPR_7 PF13176.6 EKX44845.1 - 4.4e-17 60.8 8.9 0.14 12.3 0.2 9.0 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_10 PF13374.6 EKX44845.1 - 2e-13 49.7 11.3 0.0042 16.9 0.1 8.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 EKX44845.1 - 2.2e-12 47.3 3.6 0.00029 21.3 0.2 6.8 6 2 2 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 EKX44845.1 - 3.3e-11 43.0 1.3 2.9 8.9 0.3 8.6 6 3 4 10 10 9 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX44845.1 - 4e-09 36.3 1.2 9.8e-05 21.9 0.0 3.3 1 1 2 3 3 3 2 MalT-like TPR region TPR_6 PF13174.6 EKX44845.1 - 2.2e-08 34.2 2.0 0.068 13.8 0.1 7.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX44845.1 - 4.2e-07 30.0 0.0 0.34 11.1 0.0 5.6 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 EKX44845.1 - 3.5e-06 26.5 0.4 0.0011 18.2 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 EKX44845.1 - 0.0014 18.2 0.6 0.012 15.1 0.0 2.6 3 1 1 4 4 4 1 Est1 DNA/RNA binding domain PPR PF01535.20 EKX44845.1 - 0.0075 16.4 3.9 2.9 8.4 0.0 4.6 5 0 0 5 5 3 1 PPR repeat DUF2225 PF09986.9 EKX44845.1 - 0.1 12.3 11.5 4.3 7.0 8.7 3.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) HemY_N PF07219.13 EKX44845.1 - 0.16 12.1 0.1 7.2 6.9 0.0 3.2 3 0 0 3 3 2 0 HemY protein N-terminus ANAPC3 PF12895.7 EKX44845.1 - 0.39 11.0 0.1 0.39 11.0 0.1 5.7 4 3 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 EKX44845.1 - 0.66 10.1 6.0 1.4 9.1 0.4 3.7 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat Pex2_Pex12 PF04757.14 EKX44846.1 - 1.7e-30 106.3 0.4 2.1e-30 106.0 0.4 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.25 EKX44846.1 - 0.00064 19.5 7.5 0.0014 18.4 7.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EKX44846.1 - 0.009 15.9 11.5 0.021 14.6 11.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EKX44846.1 - 0.019 15.1 6.7 0.042 14.0 6.7 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EKX44846.1 - 0.1 12.6 11.4 0.29 11.1 11.4 1.8 1 1 0 1 1 1 0 zinc-RING finger domain zf-Sec23_Sec24 PF04810.15 EKX44846.1 - 0.77 9.9 0.1 0.77 9.9 0.1 3.3 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger zinc-ribbons_6 PF07191.12 EKX44846.1 - 0.91 9.5 9.0 1.8 8.6 9.0 1.5 1 0 0 1 1 1 0 zinc-ribbons zf-RING_2 PF13639.6 EKX44846.1 - 4.7 7.6 11.1 16 5.9 11.1 1.9 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 EKX44846.1 - 6.2 6.8 11.5 0.68 9.8 6.0 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) efThoc1 PF11957.8 EKX44847.1 - 1e-70 238.8 5.4 1.6e-69 234.9 5.4 2.2 1 1 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Nmad2 PF18753.1 EKX44847.1 - 0.014 14.8 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Nucleotide modification associated domain 2 RRP36 PF06102.12 EKX44848.1 - 2.5e-17 63.3 24.5 2.5e-17 63.3 24.5 3.5 1 1 3 4 4 4 2 rRNA biogenesis protein RRP36 RbsD_FucU PF05025.13 EKX44848.1 - 0.89 10.0 3.3 1.6 9.2 2.7 1.7 1 1 1 2 2 2 0 RbsD / FucU transport protein family Bac_rhodopsin PF01036.18 EKX44849.1 - 3.7e-37 128.0 20.0 4.6e-37 127.7 20.0 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein UPF0114 PF03350.16 EKX44849.1 - 0.066 13.4 0.5 0.066 13.4 0.5 2.7 2 1 1 3 3 3 0 Uncharacterized protein family, UPF0114 Nucleos_tra2_C PF07662.13 EKX44849.1 - 0.2 11.4 11.0 0.076 12.8 4.4 2.2 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter C-terminus DUF4131 PF13567.6 EKX44849.1 - 3.5 7.2 12.0 3.3 7.3 3.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4191 PF13829.6 EKX44849.1 - 4 6.7 10.8 0.3 10.4 3.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Pkinase PF00069.25 EKX44850.1 - 2.6e-11 43.4 0.0 1.9e-10 40.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX44850.1 - 1.7e-10 40.6 0.0 2.7e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 EKX44850.1 - 1.7e-07 30.9 0.6 1.3 9.5 0.0 4.5 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.6 EKX44850.1 - 0.00065 20.0 0.0 0.0026 18.1 0.0 2.1 1 0 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.6 EKX44850.1 - 0.0037 17.7 0.1 0.73 10.4 0.3 3.1 3 0 0 3 3 3 1 HEAT-like repeat Ion_trans PF00520.31 EKX44852.1 - 4.1e-31 108.1 13.8 4.6e-31 107.9 13.8 1.0 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EKX44852.1 - 0.033 12.9 0.6 0.033 12.9 0.6 2.3 2 1 1 3 3 3 0 Polycystin cation channel PH PF00169.29 EKX44854.1 - 1.7e-08 34.9 0.0 3.6e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 PH domain IQ PF00612.27 EKX44856.1 - 5.9e-44 143.7 265.8 0.0014 18.3 0.4 38.7 38 0 0 38 38 38 30 IQ calmodulin-binding motif CH PF00307.31 EKX44856.1 - 2.2e-15 56.8 0.2 5.2e-07 29.8 0.1 3.0 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EKX44856.1 - 0.0064 16.3 0.1 1.1 9.1 0.1 3.1 2 0 0 2 2 2 1 CAMSAP CH domain CH_2 PF06294.11 EKX44856.1 - 0.31 11.2 5.6 0.57 10.3 0.0 4.2 5 0 0 5 5 5 0 CH-like domain in sperm protein DUF2835 PF11197.8 EKX44856.1 - 0.73 9.7 19.5 21 5.1 0.5 5.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2835) Rootletin PF15035.6 EKX44857.1 - 0.2 11.7 17.2 0.28 11.2 17.2 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion AAA_11 PF13086.6 EKX44857.1 - 3.8 7.2 9.6 4.9 6.9 9.6 1.1 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.19 EKX44857.1 - 4 5.2 9.9 4.9 4.9 9.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Abhydrolase_1 PF00561.20 EKX44858.1 - 4.2e-07 29.9 0.0 7.2e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EKX44858.1 - 1.8e-06 27.4 0.0 2.5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EKX44858.1 - 1.6e-05 25.6 0.7 4.9e-05 24.0 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 EKX44858.1 - 2.5e-05 23.1 0.0 3.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 EKX44858.1 - 0.00012 22.0 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EKX44858.1 - 0.0016 18.0 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family PGAP1 PF07819.13 EKX44858.1 - 0.014 15.2 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.20 EKX44858.1 - 0.041 13.5 0.4 0.066 12.8 0.4 1.3 1 0 0 1 1 1 0 Putative esterase DUF1057 PF06342.12 EKX44858.1 - 0.064 12.3 0.0 0.15 11.0 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Thioesterase PF00975.20 EKX44858.1 - 0.065 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain LIDHydrolase PF10230.9 EKX44858.1 - 0.072 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 EKX44858.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.7 EKX44858.1 - 0.1 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Pro_CA PF00484.19 EKX44858.1 - 0.2 11.9 0.0 0.39 11.0 0.0 1.4 1 0 0 1 1 1 0 Carbonic anhydrase PAS_9 PF13426.7 EKX44859.1 - 9.2e-13 48.3 0.0 9.7e-13 48.3 0.0 1.0 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EKX44859.1 - 0.0002 21.3 0.0 0.00022 21.2 0.0 1.1 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EKX44859.1 - 0.00021 21.5 0.0 0.00022 21.5 0.0 1.1 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 EKX44859.1 - 0.0021 18.3 0.0 0.0036 17.6 0.0 1.4 1 1 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EKX44859.1 - 0.028 14.4 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 PAS domain PAS_5 PF07310.13 EKX44859.1 - 0.065 13.0 0.0 0.065 13.0 0.0 1.1 1 0 0 1 1 1 0 PAS domain Ank_4 PF13637.6 EKX44860.1 - 1.7e-10 41.2 2.6 6.8e-06 26.5 0.1 2.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX44860.1 - 9.6e-08 32.5 0.3 1.5e-07 31.9 0.3 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX44860.1 - 1.4e-05 25.3 0.6 0.0039 17.5 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX44860.1 - 1.5e-05 25.0 0.2 0.033 14.7 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EKX44860.1 - 0.00063 20.1 0.9 0.0046 17.4 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat PDZ PF00595.24 EKX44861.1 - 6.6e-07 29.6 0.0 1.1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX44861.1 - 0.0001 22.1 0.1 0.00023 21.0 0.0 1.7 1 1 1 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX44861.1 - 0.0004 20.7 0.0 0.00059 20.1 0.0 1.4 1 1 0 1 1 1 1 PDZ domain MCC-bdg_PDZ PF10506.9 EKX44862.1 - 9.9e-05 22.3 3.5 9.9e-05 22.3 3.5 3.6 3 2 0 3 3 3 1 PDZ domain of MCC-2 bdg protein for Usher syndrome ATG16 PF08614.11 EKX44862.1 - 0.0046 17.2 28.3 0.0046 17.2 28.3 2.1 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) RWP-RK PF02042.15 EKX44862.1 - 0.0079 16.2 0.2 0.024 14.6 0.2 1.8 1 0 0 1 1 1 1 RWP-RK domain AbiEi_3_N PF17194.4 EKX44862.1 - 0.051 13.6 0.4 0.41 10.7 0.0 2.5 2 1 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain Leu_zip PF15294.6 EKX44862.1 - 0.69 9.4 40.5 0.042 13.4 16.6 2.1 1 1 1 2 2 2 0 Leucine zipper ERM PF00769.19 EKX44862.1 - 1.3 8.8 46.9 0.82 9.4 19.2 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Lip_prot_lig_C PF10437.9 EKX44862.1 - 1.5 8.9 4.5 6.5 6.8 0.1 2.9 3 0 0 3 3 3 0 Bacterial lipoate protein ligase C-terminus Peptidase_M2 PF01401.18 EKX44862.1 - 1.5 7.3 15.8 1 7.9 14.4 1.4 1 1 0 1 1 1 0 Angiotensin-converting enzyme ApoO PF09769.9 EKX44862.1 - 3.6 7.5 5.0 2.9 7.8 3.0 2.1 1 1 0 2 2 2 0 Apolipoprotein O Filament PF00038.21 EKX44862.1 - 4.9 6.7 38.6 14 5.1 13.1 2.9 1 1 1 2 2 2 0 Intermediate filament protein DUF812 PF05667.11 EKX44862.1 - 5.9 5.7 35.9 9.9 4.9 35.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF2408 PF10303.9 EKX44862.1 - 9.8 6.7 29.1 1.8 9.2 17.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DUF1989 PF09347.10 EKX44863.1 - 0.0063 16.2 0.1 0.0077 15.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Ephrin_rec_like PF07699.13 EKX44865.1 - 3.7e-39 132.2 75.4 1.1e-08 34.7 2.1 7.1 4 2 3 7 7 7 7 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX44865.1 - 0.016 15.6 56.1 0.37 11.2 0.5 9.5 4 3 5 9 9 9 0 TNFR/NGFR cysteine-rich region DUF4215 PF13948.6 EKX44865.1 - 0.032 14.7 12.2 0.032 14.7 12.2 5.7 4 2 0 5 5 5 0 Domain of unknown function (DUF4215) RANK_CRD_2 PF18278.1 EKX44865.1 - 0.23 11.6 0.4 0.23 11.6 0.4 5.3 5 1 0 5 5 5 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 VSP PF03302.13 EKX44865.1 - 1 8.1 68.6 0.35 9.7 30.8 3.3 1 1 0 1 1 1 0 Giardia variant-specific surface protein Kelch_6 PF13964.6 EKX44866.1 - 1.1e-26 92.2 9.9 6.1e-08 32.7 0.2 5.6 5 1 1 6 6 6 5 Kelch motif Kelch_5 PF13854.6 EKX44866.1 - 8.3e-26 89.5 10.4 4.3e-05 23.4 0.4 5.3 5 0 0 5 5 5 5 Kelch motif Kelch_1 PF01344.25 EKX44866.1 - 1.1e-25 88.9 9.1 4.9e-07 29.2 0.1 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 EKX44866.1 - 5.1e-25 87.2 13.2 8.4e-06 25.9 0.1 6.1 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 EKX44866.1 - 6.7e-24 83.6 8.7 4.8e-07 29.7 0.1 5.7 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 EKX44866.1 - 9.6e-14 50.7 5.8 0.0059 16.6 0.0 5.4 5 1 0 5 5 5 4 Kelch motif DUF212 PF02681.14 EKX44866.1 - 0.096 12.8 0.2 0.3 11.2 0.1 1.8 2 1 0 2 2 2 0 Divergent PAP2 family PQQ_3 PF13570.6 EKX44866.1 - 4.1 8.0 9.3 2.6 8.7 0.2 4.1 4 1 0 4 4 4 0 PQQ-like domain HAS-barrel PF09378.10 EKX44867.1 - 0.035 14.2 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 HAS barrel domain DUF4573 PF15140.6 EKX44867.1 - 2.4 7.9 36.6 0.074 12.8 17.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4573) TPR_17 PF13431.6 EKX44868.1 - 1.1e-30 103.8 22.7 0.00041 20.5 0.1 14.7 16 0 0 16 16 16 8 Tetratricopeptide repeat TPR_11 PF13414.6 EKX44868.1 - 9.1e-21 73.3 14.2 0.00043 19.9 0.0 12.1 14 0 0 14 14 14 4 TPR repeat TPR_14 PF13428.6 EKX44868.1 - 5.8e-19 67.2 11.3 7.7 7.6 0.0 16.2 9 4 8 18 18 18 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX44868.1 - 2.5e-17 61.9 26.6 0.012 15.4 0.1 14.1 15 2 0 15 15 15 4 Tetratricopeptide repeat TPR_2 PF07719.17 EKX44868.1 - 6.8e-17 60.2 28.7 0.0045 17.0 0.0 14.6 17 0 0 17 17 16 4 Tetratricopeptide repeat TPR_8 PF13181.6 EKX44868.1 - 3.5e-16 58.0 6.4 0.2 12.0 0.0 12.6 14 1 0 14 14 11 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX44868.1 - 3.5e-09 36.8 13.0 0.052 13.8 0.1 9.5 8 2 3 11 11 11 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX44868.1 - 5.7e-09 36.5 10.7 0.13 12.9 0.0 8.7 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.6 EKX44868.1 - 7.8e-09 35.9 19.3 0.32 11.5 0.0 11.2 10 1 1 12 12 12 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX44868.1 - 3e-06 26.8 2.2 11 6.3 0.0 9.0 13 0 0 13 13 10 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX44868.1 - 3e-05 24.1 1.5 5.2 7.3 0.0 6.7 3 1 2 6 6 6 1 Tetratricopeptide repeat Coatomer_E PF04733.14 EKX44868.1 - 0.0016 17.9 0.6 0.56 9.6 0.1 4.2 5 0 0 5 5 5 1 Coatomer epsilon subunit NTS_2 PF15448.6 EKX44868.1 - 0.011 16.1 3.8 5.7 7.4 0.0 4.7 5 0 0 5 5 5 0 N-terminal segments of P. falciparum erythrocyte membrane protein TPR_6 PF13174.6 EKX44868.1 - 0.19 12.5 10.8 37 5.2 0.0 7.4 10 0 0 10 10 8 0 Tetratricopeptide repeat PPR_2 PF13041.6 EKX44869.1 - 3.6e-24 84.7 0.1 4.1e-05 23.7 0.0 8.7 7 2 2 9 9 9 7 PPR repeat family PPR_3 PF13812.6 EKX44869.1 - 1.1e-23 83.0 0.2 8.2e-07 29.0 0.0 7.7 8 0 0 8 8 8 4 Pentatricopeptide repeat domain PPR_1 PF12854.7 EKX44869.1 - 4.5e-11 42.2 5.4 0.18 11.5 0.0 7.2 7 0 0 7 7 7 3 PPR repeat PPR_long PF17177.4 EKX44869.1 - 3.5e-08 33.1 0.0 0.34 10.2 0.0 4.6 2 2 2 5 5 5 3 Pentacotripeptide-repeat region of PRORP Glyco_trans_4_3 PF12000.8 EKX44869.1 - 0.0019 17.9 0.0 5.7 6.6 0.0 3.9 5 0 0 5 5 5 2 Glycosyl transferase family 4 group O-FucT PF10250.9 EKX44871.1 - 3.3e-09 36.9 0.6 6.2e-09 36.0 0.0 1.7 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase EF-hand_7 PF13499.6 EKX44872.1 - 2.6e-36 123.9 26.4 1.1e-10 41.8 2.0 5.1 4 1 0 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 EKX44872.1 - 3e-36 120.2 24.0 1.4e-06 27.4 1.0 8.3 8 0 0 8 8 8 6 EF hand EF-hand_5 PF13202.6 EKX44872.1 - 4.8e-35 117.5 26.3 1.4e-06 27.5 1.0 7.2 7 0 0 7 7 7 6 EF hand EF-hand_6 PF13405.6 EKX44872.1 - 2.3e-31 105.0 22.7 1.9e-05 24.2 0.4 8.1 8 0 0 8 8 8 6 EF-hand domain EF-hand_8 PF13833.6 EKX44872.1 - 4.3e-23 80.9 28.6 1.3e-07 31.3 2.6 6.6 5 3 3 8 8 8 6 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX44872.1 - 1.5e-11 44.6 13.4 2e-05 24.9 0.2 4.5 3 2 1 4 4 4 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EKX44872.1 - 0.00063 20.0 6.0 0.19 12.1 0.1 4.0 4 1 0 4 4 4 2 EF-hand domain EF-hand_4 PF12763.7 EKX44872.1 - 0.0027 17.6 16.2 0.94 9.5 0.4 5.0 2 1 2 5 5 5 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 EKX44872.1 - 0.012 15.6 1.3 3.4 7.6 0.0 4.2 3 2 2 5 5 5 0 Caleosin related protein Muted PF14942.6 EKX44872.1 - 0.034 14.5 1.5 0.034 14.5 1.5 2.1 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein PMBR PF09373.10 EKX44872.1 - 0.048 13.8 0.2 59 4.1 0.0 5.1 7 0 0 7 7 7 0 Pseudomurein-binding repeat p25-alpha PF05517.12 EKX44872.1 - 0.058 13.6 5.0 11 6.1 0.2 4.1 3 1 0 4 4 4 0 p25-alpha MvaI_BcnI PF15515.6 EKX44872.1 - 0.14 11.9 5.4 0.056 13.3 1.6 1.9 1 1 1 2 2 2 0 MvaI/BcnI restriction endonuclease family Sigma70_r1_1 PF03979.14 EKX44872.1 - 0.79 9.8 6.2 0.65 10.1 0.1 3.4 4 0 0 4 4 4 0 Sigma-70 factor, region 1.1 SesA PF17107.5 EKX44872.1 - 5.8 7.1 7.8 1.6 9.0 1.1 3.3 3 1 1 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Bac_rhodopsin PF01036.18 EKX44873.1 - 3.3e-20 72.6 10.8 4e-20 72.4 10.8 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein TPR_1 PF00515.28 EKX44874.1 - 6.9e-48 158.6 1.0 3.3e-09 36.2 0.0 7.9 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 EKX44874.1 - 4.4e-42 141.5 5.3 3.2e-09 36.3 0.0 7.3 2 2 5 7 7 7 6 TPR repeat TPR_8 PF13181.6 EKX44874.1 - 1e-39 131.4 1.8 9e-06 25.5 0.0 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 EKX44874.1 - 1.3e-38 128.0 1.0 2.3e-06 27.3 0.0 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.6 EKX44874.1 - 4.9e-34 114.3 0.2 0.00038 20.6 0.0 7.6 7 0 0 7 7 7 7 Tetratricopeptide repeat Glyco_transf_41 PF13844.6 EKX44874.1 - 1.2e-32 112.9 0.2 6e-27 94.2 0.0 3.0 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_16 PF13432.6 EKX44874.1 - 6.4e-32 109.9 0.3 4.9e-07 30.3 0.0 6.1 1 1 6 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.6 EKX44874.1 - 1.2e-29 102.4 9.6 5.9e-08 32.9 0.5 5.8 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 EKX44874.1 - 1.3e-20 71.8 0.2 0.012 15.6 0.0 7.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 EKX44874.1 - 1.2e-17 63.1 0.2 0.044 14.6 0.0 8.1 1 1 7 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 EKX44874.1 - 4e-16 59.3 0.0 0.013 16.0 0.0 5.5 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_6 PF13174.6 EKX44874.1 - 5.6e-15 54.9 0.0 0.11 13.2 0.0 6.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX44874.1 - 7.7e-14 51.1 11.3 0.13 12.2 0.4 7.8 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_9 PF13371.6 EKX44874.1 - 4.9e-11 42.6 0.0 0.00096 19.3 0.0 5.4 2 2 2 5 5 5 1 Tetratricopeptide repeat ANAPC5 PF12862.7 EKX44874.1 - 5.8e-07 29.5 2.4 0.95 9.6 0.0 4.8 3 2 2 5 5 4 2 Anaphase-promoting complex subunit 5 TPR_MalT PF17874.1 EKX44874.1 - 3.2e-06 26.7 3.2 0.034 13.5 0.0 3.7 1 1 2 3 3 3 2 MalT-like TPR region TPR_4 PF07721.14 EKX44874.1 - 0.00055 20.3 0.9 22 6.1 0.0 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat NARP1 PF12569.8 EKX44874.1 - 0.0012 17.9 0.6 0.12 11.2 0.3 2.9 1 1 1 3 3 3 1 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 EKX44874.1 - 0.0026 18.1 0.0 4.1 7.8 0.0 3.4 1 1 1 3 3 3 1 Tetratricopeptide repeat DUF627 PF04781.12 EKX44874.1 - 0.03 14.3 0.4 1.2 9.2 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF627) FAT PF02259.23 EKX44874.1 - 0.036 13.3 1.1 0.34 10.1 1.1 2.6 1 1 0 1 1 1 0 FAT domain TOM20_plant PF06552.12 EKX44874.1 - 0.078 12.7 0.1 1.2 8.9 0.0 2.6 1 1 1 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 DASH_Duo1 PF08651.10 EKX44874.1 - 0.092 12.5 0.0 27 4.6 0.0 3.0 3 0 0 3 3 2 0 DASH complex subunit Duo1 TPR_12 PF13424.6 EKX44875.1 - 5.9e-20 71.3 5.8 1.2e-11 44.7 0.1 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX44875.1 - 2.2e-14 52.3 3.1 0.0014 18.5 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX44875.1 - 1.5e-12 46.7 4.6 0.0008 19.1 0.0 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX44875.1 - 3.7e-09 36.0 11.7 0.026 14.5 0.0 6.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX44875.1 - 3e-08 33.2 3.7 0.005 16.9 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX44875.1 - 2.2e-06 27.3 1.1 0.045 13.1 0.1 3.3 3 0 0 3 3 3 2 MalT-like TPR region TPR_11 PF13414.6 EKX44875.1 - 2.3e-05 24.0 2.5 0.53 10.0 0.0 4.4 4 0 0 4 4 4 2 TPR repeat TPR_19 PF14559.6 EKX44875.1 - 0.00093 19.7 0.7 5.7 7.5 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat C2 PF00168.30 EKX44875.1 - 0.0011 19.2 0.0 0.0041 17.4 0.0 2.0 1 0 0 1 1 1 1 C2 domain TPR_10 PF13374.6 EKX44875.1 - 0.0012 18.6 20.6 0.029 14.2 0.6 6.3 7 0 0 7 7 6 2 Tetratricopeptide repeat MIT PF04212.18 EKX44875.1 - 0.0063 16.5 8.6 0.91 9.6 0.0 5.5 6 0 0 6 6 6 1 MIT (microtubule interacting and transport) domain DUF2570 PF10828.8 EKX44875.1 - 0.021 14.6 5.7 0.018 14.9 2.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) TPR_16 PF13432.6 EKX44875.1 - 0.039 14.6 0.0 11 6.8 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX44875.1 - 0.072 13.8 0.0 2.6 8.9 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_8 PF13855.6 EKX44876.1 - 1.3e-17 63.2 11.2 2.6e-07 30.3 0.1 3.6 1 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 EKX44876.1 - 1.1e-11 44.8 10.2 0.00033 21.0 0.3 4.6 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) CREPT PF16566.5 EKX44876.1 - 0.016 15.4 0.0 7.8 6.7 0.0 2.8 1 1 2 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour LRR_9 PF14580.6 EKX44876.1 - 0.033 13.7 0.3 0.95 8.9 0.1 2.2 1 1 1 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 EKX44876.1 - 2.1 8.6 4.9 7.3 6.9 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 EKX44876.1 - 7.3 7.6 14.1 54 4.9 0.1 5.4 4 2 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.6 EKX44877.1 - 1.2e-47 159.5 81.4 3.4e-09 36.3 1.9 10.8 5 2 5 12 12 12 11 Leucine rich repeat LRR_4 PF12799.7 EKX44877.1 - 1.5e-44 149.3 86.6 4.5e-05 23.7 5.0 14.0 8 3 5 16 16 16 13 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX44877.1 - 3.2e-09 36.1 76.4 1.2 9.9 0.7 18.7 19 1 0 19 19 19 5 Leucine Rich Repeat LRR_6 PF13516.6 EKX44877.1 - 0.0024 17.8 55.8 0.4 10.8 0.9 14.3 16 0 0 16 16 16 3 Leucine Rich repeat RsmF_methylt_CI PF17126.5 EKX44877.1 - 0.0024 17.9 2.1 2.3 8.3 0.4 5.5 6 1 1 7 7 7 1 RsmF rRNA methyltransferase first C-terminal domain DUF2322 PF10084.9 EKX44877.1 - 0.036 14.1 0.1 16 5.6 0.0 4.5 3 2 3 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2322) CdiI_2 PF18593.1 EKX44878.1 - 0.13 12.9 5.7 7.8 7.2 0.3 3.8 3 0 0 3 3 3 0 CdiI immunity protein SIMPL PF04402.14 EKX44878.1 - 4.9 7.5 7.5 4 7.8 2.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF541) DNA_topoisoIV PF00521.20 EKX44879.1 - 3.7e-50 171.1 3.9 9.6e-44 149.9 0.0 4.5 4 1 0 4 4 4 3 DNA gyrase/topoisomerase IV, subunit A HATPase_c PF02518.26 EKX44879.1 - 1.3e-05 25.6 0.0 3.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EKX44879.1 - 0.00035 20.7 0.0 0.0012 19.0 0.0 1.9 1 0 0 1 1 1 1 Toprim domain TOPRIM_C PF16898.5 EKX44879.1 - 0.0004 20.7 0.3 0.0004 20.7 0.3 2.4 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM HTH_33 PF13592.6 EKX44879.1 - 0.048 13.3 1.0 0.23 11.1 0.0 2.7 3 0 0 3 3 3 0 Winged helix-turn helix DUF4224 PF13986.6 EKX44880.1 - 0.063 13.2 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) IQ PF00612.27 EKX44880.1 - 0.081 12.8 0.7 0.26 11.2 0.1 2.3 2 0 0 2 2 2 0 IQ calmodulin-binding motif NHL PF01436.21 EKX44881.1 - 8.1e-12 44.6 0.7 0.0023 17.9 0.0 4.4 4 1 0 4 4 4 3 NHL repeat Arylesterase PF01731.20 EKX44881.1 - 2.9e-08 33.8 0.0 0.00085 19.5 0.0 3.1 3 0 0 3 3 3 2 Arylesterase SGL PF08450.12 EKX44881.1 - 0.0002 21.0 0.4 0.26 10.8 0.1 2.9 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 EKX44881.1 - 0.00071 18.9 0.0 0.26 10.5 0.0 2.2 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller ANAPC4_WD40 PF12894.7 EKX44881.1 - 0.029 14.7 0.0 0.95 9.8 0.0 2.7 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RadC PF04002.15 EKX44881.1 - 0.08 12.9 0.0 2.4 8.1 0.0 2.7 3 0 0 3 3 3 0 RadC-like JAB domain WD40 PF00400.32 EKX44881.1 - 0.14 13.0 0.6 3.2 8.8 0.1 3.0 2 2 1 3 3 3 0 WD domain, G-beta repeat DUF1993 PF09351.10 EKX44882.1 - 2.4 8.3 7.7 2.1 8.5 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) Prominin PF05478.11 EKX44882.1 - 2.4 6.0 7.9 0.034 12.1 0.7 1.4 2 0 0 2 2 2 0 Prominin DUF883 PF05957.13 EKX44882.1 - 3.4 8.3 8.9 0.8 10.4 1.8 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) GTP_EFTU PF00009.27 EKX44883.1 - 8.7e-42 142.9 0.0 1.3e-41 142.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EKX44883.1 - 1.1e-31 109.4 0.1 5.3e-31 107.2 0.0 2.3 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EKX44883.1 - 1.3e-06 28.7 0.5 5.3e-06 26.7 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EKX44883.1 - 0.00057 20.0 0.0 0.0049 16.9 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2250 PF10007.9 EKX44883.1 - 0.12 12.5 0.7 0.42 10.8 0.7 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) PAM2 PF07145.15 EKX44883.1 - 4.2 7.3 5.8 4.4 7.2 3.0 2.4 1 1 1 2 2 2 0 Ataxin-2 C-terminal region Asn_synthase PF00733.21 EKX44885.1 - 1.4e-86 291.4 0.1 4.2e-50 171.4 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EKX44885.1 - 2.6e-32 111.3 0.0 8.2e-32 109.7 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EKX44885.1 - 2.7e-22 79.4 0.1 4.5e-20 72.2 0.0 2.9 2 1 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EKX44885.1 - 1.7e-05 24.4 0.1 4.2e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Aluminium induced protein DUF1933 PF09147.10 EKX44885.1 - 0.0049 16.5 0.0 0.0083 15.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1933) NAD_synthase PF02540.17 EKX44885.1 - 0.055 12.6 0.0 0.091 11.9 0.0 1.3 1 0 0 1 1 1 0 NAD synthase TruD PF01142.18 EKX44886.1 - 4.3e-84 282.8 0.4 5.8e-77 259.3 0.1 3.3 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Tmemb_14 PF03647.13 EKX44887.1 - 2.2e-23 82.8 10.7 2.5e-23 82.6 10.7 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C 7TMR-DISM_7TM PF07695.11 EKX44887.1 - 0.14 12.1 1.7 0.19 11.6 1.6 1.4 1 1 0 1 1 1 0 7TM diverse intracellular signalling Xpo1 PF08389.12 EKX44889.1 - 1.1e-24 87.2 0.4 6e-24 84.8 0.1 2.6 2 0 0 2 2 2 1 Exportin 1-like protein Baculo_PEP_C PF04513.12 EKX44889.1 - 0.16 12.0 3.1 0.42 10.7 0.4 2.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Polyketide_cyc2 PF10604.9 EKX44890.1 - 1.7e-09 38.1 0.0 3.9e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EKX44890.1 - 2e-06 28.1 0.0 1.4e-05 25.3 0.0 2.3 2 1 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Beta_helix PF13229.6 EKX44891.1 - 4.7e-09 36.3 13.9 1.3e-07 31.6 1.8 2.2 2 0 0 2 2 2 2 Right handed beta helix region NosD PF05048.13 EKX44891.1 - 5.9e-06 25.7 6.9 5.9e-05 22.4 0.1 2.2 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) F-box PF00646.33 EKX44891.1 - 2.6e-05 24.0 0.3 4.9e-05 23.1 0.3 1.5 1 0 0 1 1 1 1 F-box domain Fucokinase PF07959.12 EKX44891.1 - 0.03 13.3 0.5 0.041 12.8 0.5 1.4 1 0 0 1 1 1 0 L-fucokinase RWP-RK PF02042.15 EKX44892.1 - 7.5e-15 54.6 0.1 1.1e-14 54.1 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX44893.1 - 7.5e-15 54.6 0.1 1.1e-14 54.1 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX44894.1 - 5e-15 55.2 0.1 7.9e-15 54.6 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX44895.1 - 7.5e-15 54.6 0.1 1.1e-14 54.1 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX44896.1 - 3.5e-15 55.7 0.1 5.2e-15 55.1 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX44897.1 - 3.5e-15 55.7 0.1 5.2e-15 55.1 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX44898.1 - 3.5e-15 55.7 0.1 5.2e-15 55.1 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX44899.1 - 3.5e-15 55.7 0.1 5.2e-15 55.1 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX44900.1 - 3.5e-15 55.7 0.1 5.2e-15 55.1 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain BACK PF07707.15 EKX44901.1 - 1.2e-08 34.9 0.0 2.1e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 BTB And C-terminal Kelch SLC3A2_N PF16028.5 EKX44901.1 - 0.0062 16.1 0.6 0.0062 16.1 0.6 2.1 2 0 0 2 2 2 1 Solute carrier family 3 member 2 N-terminus fn3 PF00041.21 EKX44902.1 - 1.9e-91 300.6 0.2 1.6e-12 47.6 0.0 10.1 9 1 1 10 10 10 9 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 EKX44902.1 - 3.3e-15 56.4 0.7 0.0095 16.5 0.0 8.6 9 0 0 9 9 9 4 Purple acid Phosphatase, N-terminal domain SusE PF14292.6 EKX44902.1 - 3.2e-05 24.1 0.0 2.6 8.3 0.0 5.8 6 0 0 6 6 6 1 SusE outer membrane protein Interfer-bind PF09294.10 EKX44902.1 - 0.24 11.7 5.1 8.8 6.7 0.1 4.2 5 0 0 5 5 5 0 Interferon-alpha/beta receptor, fibronectin type III CAP_N PF01213.19 EKX44902.1 - 1.8 8.0 11.4 6.6 6.1 4.2 2.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal TPR_12 PF13424.6 EKX44903.1 - 3e-99 325.4 30.2 2.6e-12 46.8 0.0 11.2 8 2 2 11 11 11 11 Tetratricopeptide repeat TPR_1 PF00515.28 EKX44903.1 - 1.3e-69 227.4 42.5 3.7e-07 29.7 0.1 19.5 19 1 0 19 19 19 14 Tetratricopeptide repeat TPR_2 PF07719.17 EKX44903.1 - 6e-64 207.1 42.3 0.00021 21.2 0.0 18.7 19 0 0 19 19 19 13 Tetratricopeptide repeat TPR_7 PF13176.6 EKX44903.1 - 6.8e-56 182.3 31.7 3.6e-07 29.7 0.6 17.7 18 0 0 18 18 18 11 Tetratricopeptide repeat TPR_8 PF13181.6 EKX44903.1 - 6.1e-52 169.5 41.4 0.0017 18.4 0.1 18.4 19 1 0 19 19 19 10 Tetratricopeptide repeat TPR_10 PF13374.6 EKX44903.1 - 2e-51 170.6 23.5 7.4e-05 22.5 1.2 17.4 19 0 0 19 19 17 10 Tetratricopeptide repeat SNAP PF14938.6 EKX44903.1 - 3.5e-29 102.1 22.5 8.4e-07 28.7 4.4 6.4 2 2 5 7 7 7 6 Soluble NSF attachment protein, SNAP TPR_14 PF13428.6 EKX44903.1 - 5.5e-23 79.7 8.4 1.3 10.0 0.0 14.3 14 3 3 17 17 13 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX44903.1 - 2.2e-22 79.9 8.2 2.9e-06 26.9 1.0 6.1 2 1 2 6 6 6 4 MalT-like TPR region TPR_16 PF13432.6 EKX44903.1 - 2e-21 76.3 0.3 0.15 12.7 0.0 10.8 10 2 2 12 12 12 5 Tetratricopeptide repeat TPR_6 PF13174.6 EKX44903.1 - 3.2e-20 71.4 26.4 0.11 13.2 0.0 14.7 15 1 0 15 15 12 4 Tetratricopeptide repeat TPR_11 PF13414.6 EKX44903.1 - 5.1e-20 70.9 12.3 0.0012 18.5 0.0 14.2 15 2 1 16 16 15 3 TPR repeat RPN7 PF10602.9 EKX44903.1 - 3.7e-18 65.8 21.9 0.018 14.8 0.4 9.2 3 2 4 7 7 7 5 26S proteasome subunit RPN7 TPR_9 PF13371.6 EKX44903.1 - 4.1e-11 42.9 12.4 0.73 10.0 0.1 9.7 10 1 1 11 11 10 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX44903.1 - 3.6e-10 40.2 18.0 0.073 13.6 0.0 9.5 9 2 2 11 11 9 2 Tetratricopeptide repeat TPR_15 PF13429.6 EKX44903.1 - 4.4e-08 32.7 0.2 0.26 10.4 0.0 5.8 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX44903.1 - 6.3e-08 32.5 16.4 21 5.8 0.0 11.9 13 3 0 13 13 9 0 Tetratricopeptide repeat DUF2225 PF09986.9 EKX44903.1 - 8.5e-07 28.9 14.0 0.045 13.5 6.4 6.1 3 3 1 4 4 4 2 Uncharacterized protein conserved in bacteria (DUF2225) ANAPC5 PF12862.7 EKX44903.1 - 5.2e-06 26.4 14.3 0.11 12.6 0.1 6.9 5 2 2 7 7 7 2 Anaphase-promoting complex subunit 5 TPR_20 PF14561.6 EKX44903.1 - 0.00038 20.7 0.9 2.2 8.7 0.0 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat DUF3856 PF12968.7 EKX44903.1 - 0.00042 20.4 10.0 0.2 11.7 1.0 6.4 3 2 3 6 6 6 1 Domain of Unknown Function (DUF3856) TPR_21 PF09976.9 EKX44903.1 - 0.0019 17.9 1.8 15 5.2 0.0 6.0 4 2 3 7 7 7 0 Tetratricopeptide repeat-like domain DUF5113 PF17140.4 EKX44903.1 - 0.0077 16.0 4.8 0.19 11.6 0.6 4.5 3 2 2 5 5 5 1 Domain of unknown function (DUF5113) SHNi-TPR PF10516.9 EKX44903.1 - 0.008 15.6 13.8 0.92 9.0 0.1 6.9 7 0 0 7 7 6 1 SHNi-TPR Imm5 PF14423.6 EKX44903.1 - 0.017 15.3 1.8 0.39 10.9 0.3 2.4 2 0 0 2 2 2 0 Immunity protein Imm5 RPN6_N PF18055.1 EKX44903.1 - 0.022 15.1 3.7 36 4.7 0.0 5.6 4 1 3 7 7 7 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_4 PF07721.14 EKX44903.1 - 0.025 15.2 6.2 96 4.1 2.3 5.5 5 0 0 5 5 3 0 Tetratricopeptide repeat Prefoldin PF02996.17 EKX44903.1 - 0.034 14.1 0.2 38 4.2 0.0 4.2 4 1 0 4 4 4 0 Prefoldin subunit TRAPPC9-Trs120 PF08626.11 EKX44903.1 - 0.058 10.7 0.0 0.12 9.7 0.0 1.4 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Foie-gras_1 PF11817.8 EKX44903.1 - 0.075 12.6 7.9 1.9 8.0 0.2 4.2 3 1 0 4 4 4 0 Foie gras liver health family 1 ANAPC3 PF12895.7 EKX44903.1 - 0.14 12.4 32.3 7.6 6.8 0.2 8.8 6 4 4 10 10 10 0 Anaphase-promoting complex, cyclosome, subunit 3 SGTA_dimer PF16546.5 EKX44903.1 - 0.39 10.5 4.3 10 6.0 0.1 3.8 4 0 0 4 4 4 0 Homodimerisation domain of SGTA MAS20 PF02064.15 EKX44903.1 - 0.88 9.7 5.0 24 5.0 0.1 4.9 5 1 0 5 5 4 0 MAS20 protein import receptor PPR PF01535.20 EKX44903.1 - 1.1 9.7 8.3 77 3.9 0.4 6.6 6 0 0 6 6 5 0 PPR repeat Acetyltransf_10 PF13673.7 EKX44904.1 - 4.3e-11 42.9 0.0 6.6e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EKX44904.1 - 8.4e-11 42.1 0.0 1.1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EKX44904.1 - 6.8e-09 36.0 0.0 1.1e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NodA PF02474.15 EKX44904.1 - 0.0066 16.2 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein A (NodA) LRR_6 PF13516.6 EKX44905.1 - 2.4e-08 33.4 3.7 0.2 11.8 0.1 3.2 3 0 0 3 3 3 3 Leucine Rich repeat LRR_4 PF12799.7 EKX44905.1 - 9.2e-05 22.7 2.1 0.012 16.1 0.7 2.3 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX44905.1 - 0.00032 20.4 4.1 0.16 11.8 0.4 3.0 1 1 0 2 2 2 2 Leucine rich repeat BT1 PF03092.16 EKX44907.1 - 5e-73 246.1 14.2 1.2e-44 152.5 3.0 2.5 2 1 0 2 2 2 2 BT1 family DUF5367 PF17329.2 EKX44907.1 - 0.045 13.9 0.3 0.2 11.8 0.3 2.2 1 0 0 1 1 1 0 Family of unknown function (DUF5367) OGFr_N PF04664.13 EKX44908.1 - 4.6e-59 199.5 0.4 5.4e-59 199.2 0.4 1.0 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region MORN PF02493.20 EKX44909.1 - 5.3e-52 170.7 82.0 1.2e-06 28.1 1.3 15.5 15 1 0 15 15 15 14 MORN repeat SM-ATX PF14438.6 EKX44909.1 - 0.39 10.9 0.9 65 3.8 0.0 3.3 3 0 0 3 3 3 0 Ataxin 2 SM domain C6_DPF PF10170.9 EKX44910.1 - 1.2e-14 54.5 3.6 1.3e-14 54.3 3.6 1.1 1 0 0 1 1 1 1 Cysteine-rich domain SNF2_N PF00176.23 EKX44911.1 - 3.6e-68 229.8 1.8 7.8e-68 228.7 1.8 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain HSA PF07529.13 EKX44911.1 - 1.6e-17 63.5 7.5 1.6e-17 63.5 7.5 3.8 2 1 1 3 3 3 1 HSA Helicase_C PF00271.31 EKX44911.1 - 2.5e-17 63.2 0.2 1.1e-16 61.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX44911.1 - 3.5e-11 43.4 0.2 1.9e-10 41.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EKX44911.1 - 6.1e-06 26.1 0.0 2.1e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 EKX44911.1 - 0.095 12.3 0.5 0.95 9.1 0.0 2.4 2 0 0 2 2 2 0 DEAD_2 Peptidase_S74 PF13884.6 EKX44912.1 - 0.097 13.0 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Chaperone of endosialidase Val_tRNA-synt_C PF10458.9 EKX44912.1 - 0.12 12.7 3.7 0.22 11.8 3.7 1.3 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm Fae PF08714.11 EKX44913.1 - 0.094 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Formaldehyde-activating enzyme (Fae) PKD_channel PF08016.12 EKX44914.1 - 1.5e-65 221.5 16.8 1.1e-64 218.7 16.8 1.9 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 EKX44914.1 - 5.1e-11 42.3 23.9 1e-10 41.3 23.9 1.5 1 0 0 1 1 1 1 Ion transport protein EF-hand_5 PF13202.6 EKX44914.1 - 6.2e-08 31.8 2.1 0.0029 17.0 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 EKX44914.1 - 1.5e-07 30.5 2.1 0.00077 18.8 0.3 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX44914.1 - 1e-05 25.1 0.6 0.086 12.8 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EKX44914.1 - 2.1e-05 24.8 1.4 6.5e-05 23.3 0.4 2.4 2 1 0 2 2 2 1 EF-hand domain pair Syntaxin PF00804.25 EKX44914.1 - 0.66 9.6 5.6 0.25 11.0 0.5 2.1 2 0 0 2 2 2 0 Syntaxin Laminin_II PF06009.12 EKX44914.1 - 1.2 9.1 4.5 0.41 10.7 1.1 1.9 2 0 0 2 2 2 0 Laminin Domain II Pox_A14 PF05767.12 EKX44914.1 - 1.8 8.8 6.8 0.77 9.9 2.5 2.5 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 MHCassoc_trimer PF08831.10 EKX44915.1 - 0.35 10.9 18.5 14 5.8 1.1 4.2 1 1 3 4 4 4 0 Class II MHC-associated invariant chain trimerisation domain Pkinase_Tyr PF07714.17 EKX44916.1 - 1e-23 84.0 0.0 1.2e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX44916.1 - 7.2e-07 28.8 0.0 9.4e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 EKX44917.1 - 2.4e-06 27.1 0.1 5.1e-06 26.0 0.1 1.6 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 EKX44917.1 - 7.3e-05 22.8 0.1 0.00098 19.1 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family PIP49_C PF12260.8 EKX44917.1 - 0.059 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 FTA2 PF13095.6 EKX44917.1 - 0.085 12.5 0.1 4.8 6.7 0.0 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 U-box PF04564.15 EKX44918.1 - 5.8e-12 45.6 0.0 7.4e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 EKX44918.1 - 0.00024 21.2 0.0 0.00025 21.1 0.0 1.1 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 EKX44918.1 - 0.00032 20.4 0.0 0.00042 20.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Kazal_1 PF00050.21 EKX44918.1 - 0.0019 18.2 0.0 0.0022 17.9 0.0 1.2 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 EKX44918.1 - 0.016 15.4 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain NYD-SP28 PF14772.6 EKX44919.1 - 4.8e-27 94.0 6.7 4.8e-27 94.0 6.7 5.1 5 1 0 5 5 5 2 Sperm tail NYD-SP28_assoc PF14775.6 EKX44919.1 - 4.5e-18 65.1 3.5 4.5e-18 65.1 3.5 4.7 4 1 1 5 5 5 1 Sperm tail C-terminal domain DUF749 PF05370.11 EKX44919.1 - 0.28 11.3 3.2 0.29 11.2 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF749) DUF948 PF06103.11 EKX44919.1 - 9 6.6 6.6 13 6.1 0.5 3.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Kinesin PF00225.23 EKX44920.1 - 1.3e-95 320.1 0.1 2.2e-95 319.4 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX44920.1 - 4.2e-23 81.9 0.0 1.2e-22 80.5 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding CCDC92 PF14916.6 EKX44920.1 - 0.0049 16.6 0.1 0.013 15.3 0.1 1.6 1 0 0 1 1 1 1 Coiled-coil domain of unknown function HIP1_clath_bdg PF16515.5 EKX44920.1 - 0.014 16.0 9.1 1.4 9.6 0.5 2.9 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Herpes_BLRF2 PF05812.12 EKX44920.1 - 0.018 15.2 0.2 0.056 13.6 0.2 1.8 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein PRKG1_interact PF15898.5 EKX44920.1 - 0.033 15.1 0.6 0.033 15.1 0.6 3.1 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain CdiI_2 PF18593.1 EKX44920.1 - 0.065 13.9 0.1 3.3 8.4 0.1 2.9 2 0 0 2 2 2 0 CdiI immunity protein SlyX PF04102.12 EKX44920.1 - 0.12 13.0 1.4 0.54 10.9 0.8 2.4 2 0 0 2 2 2 0 SlyX GIT_CC PF16559.5 EKX44920.1 - 0.41 10.5 3.9 0.54 10.2 2.2 2.1 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.15 EKX44920.1 - 1.5 8.6 6.2 0.16 11.7 0.7 2.2 2 0 0 2 2 2 0 Septum formation initiator Peptidase_M20 PF01546.28 EKX44921.1 - 4.6e-30 104.9 0.8 1.3e-29 103.4 0.8 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EKX44921.1 - 6.1e-05 22.9 1.9 8.7e-05 22.4 0.3 2.0 2 0 0 2 2 2 1 Peptidase dimerisation domain MukF_C PF17193.4 EKX44921.1 - 0.15 12.2 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 MukF C-terminal domain DEAD PF00270.29 EKX44924.1 - 3.6e-16 59.4 0.0 1.1e-15 57.8 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EKX44924.1 - 1.2e-11 44.9 0.0 7.6e-11 42.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EKX44924.1 - 5.8e-06 26.6 0.0 2.6e-05 24.5 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EKX44924.1 - 0.04 14.2 0.2 0.38 11.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain FAM195 PF14799.6 EKX44924.1 - 0.056 13.8 1.8 0.58 10.5 0.3 3.1 3 0 0 3 3 3 0 FAM195 family DUF758 PF05527.11 EKX44924.1 - 0.26 11.3 5.5 1.7 8.6 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF758) T3SS_basalb_I PF17001.5 EKX44924.1 - 0.54 10.9 9.5 0.11 13.1 3.0 3.2 2 0 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI RPAP1_N PF08621.10 EKX44924.1 - 2.4 8.0 6.9 4.4 7.2 1.2 2.9 2 0 0 2 2 2 0 RPAP1-like, N-terminal Beta_helix PF13229.6 EKX44925.1 - 8e-35 120.0 26.6 2.1e-21 76.4 15.0 2.7 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 EKX44925.1 - 1.1e-22 80.5 12.1 4.6e-09 35.9 7.9 3.1 1 1 2 3 3 3 3 Periplasmic copper-binding protein (NosD) Pectinesterase PF01095.19 EKX44925.1 - 0.17 10.6 0.3 0.34 9.6 0.3 1.4 1 1 0 1 1 1 0 Pectinesterase Metallophos PF00149.28 EKX44927.1 - 1.6e-24 87.6 0.8 2.8e-24 86.8 0.3 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Pox_A28 PF04584.14 EKX44928.1 - 0.15 12.2 0.6 1.6 8.9 0.3 1.9 1 1 1 2 2 2 0 Poxvirus A28 family Ras PF00071.22 EKX44929.1 - 7.8e-42 142.6 0.1 9e-42 142.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EKX44929.1 - 2e-24 86.1 0.0 2.9e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EKX44929.1 - 2.8e-12 46.4 0.0 3.2e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EKX44929.1 - 6.2e-05 22.5 0.0 7.2e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 EKX44929.1 - 0.0022 17.8 0.9 0.26 11.0 0.1 2.2 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 EKX44929.1 - 0.0026 17.8 0.0 0.0037 17.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EKX44929.1 - 0.0042 17.5 0.0 0.0045 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EKX44929.1 - 0.017 15.0 0.0 0.47 10.4 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 EKX44929.1 - 0.034 13.7 0.1 0.072 12.6 0.0 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region GTP_EFTU PF00009.27 EKX44929.1 - 0.039 13.5 0.1 0.13 11.8 0.1 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Sigma54_activat PF00158.26 EKX44929.1 - 0.046 13.4 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.6 EKX44929.1 - 0.048 13.9 0.0 0.083 13.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 EKX44929.1 - 0.067 13.2 0.0 3.7 7.6 0.0 2.1 1 1 1 2 2 2 0 Dynamin family NACHT PF05729.12 EKX44929.1 - 0.074 13.0 0.0 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 EKX44929.1 - 0.096 11.9 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain TniB PF05621.11 EKX44929.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein DUF3376 PF11856.8 EKX44929.1 - 0.25 10.3 0.0 0.33 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3376) PhyH PF05721.13 EKX44930.1 - 1.4e-12 48.3 0.1 5.5e-12 46.4 0.1 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 EKX44930.1 - 0.0037 16.1 0.0 0.3 9.8 0.0 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) UCH PF00443.29 EKX44931.1 - 7.2e-12 45.3 0.1 8.3e-12 45.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UIM PF02809.20 EKX44931.1 - 0.0015 18.3 15.8 0.0037 17.1 0.3 2.7 3 0 0 3 3 3 2 Ubiquitin interaction motif UCH_1 PF13423.6 EKX44931.1 - 0.012 15.2 0.1 0.012 15.2 0.1 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase SPRY PF00622.28 EKX44932.1 - 3.1e-15 56.3 0.1 3.4e-15 56.2 0.1 1.0 1 0 0 1 1 1 1 SPRY domain GTP_EFTU PF00009.27 EKX44935.1 - 4.1e-48 163.5 0.0 6.9e-48 162.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RF3_C PF16658.5 EKX44935.1 - 1.1e-42 144.9 0.0 2.4e-42 143.9 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 EKX44935.1 - 3.1e-07 30.7 0.0 5.8e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EKX44935.1 - 2.5e-05 24.3 0.0 4.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 EKX44935.1 - 0.038 14.1 0.0 0.085 13.0 0.0 1.6 1 1 0 1 1 1 0 Elongation Factor G, domain II SRPRB PF09439.10 EKX44935.1 - 0.058 12.8 0.0 0.3 10.5 0.0 2.0 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EKX44935.1 - 0.19 11.3 0.0 3.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B Ank_2 PF12796.7 EKX44936.1 - 2.5e-24 85.6 0.1 6.2e-17 62.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX44936.1 - 2.1e-21 76.0 0.3 1.5e-07 31.8 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX44936.1 - 1.6e-20 72.9 0.4 5.5e-11 42.5 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX44936.1 - 1.1e-16 60.4 0.4 4.6e-06 26.8 0.3 3.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EKX44936.1 - 6.7e-15 53.7 0.0 0.00029 21.1 0.1 3.7 4 0 0 4 4 4 3 Ankyrin repeat FYVE PF01363.21 EKX44937.1 - 1.2e-20 73.4 8.3 1.3e-20 73.3 8.3 1.0 1 0 0 1 1 1 1 FYVE zinc finger zf-C3HC4_4 PF15227.6 EKX44937.1 - 0.054 13.7 3.8 0.054 13.7 3.8 2.5 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING FYVE_2 PF02318.16 EKX44937.1 - 0.089 13.0 8.4 0.12 12.6 8.4 1.3 1 1 0 1 1 1 0 FYVE-type zinc finger zf-RING_UBOX PF13445.6 EKX44937.1 - 0.09 12.8 11.7 0.75 9.9 11.7 2.5 1 1 0 1 1 1 0 RING-type zinc-finger DZR PF12773.7 EKX44937.1 - 0.25 11.4 9.1 13 5.9 2.1 2.4 1 1 1 2 2 2 0 Double zinc ribbon DUF35_N PF12172.8 EKX44937.1 - 0.96 9.4 16.4 1.5 8.8 6.1 3.6 2 1 1 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Zn-ribbon_8 PF09723.10 EKX44937.1 - 1.2 9.3 12.7 6.8 6.9 0.4 3.0 1 1 1 2 2 2 0 Zinc ribbon domain zf-RING_2 PF13639.6 EKX44937.1 - 1.4 9.3 14.7 6.9 7.1 14.7 2.2 1 1 0 1 1 1 0 Ring finger domain IBR PF01485.21 EKX44937.1 - 1.5 9.1 14.9 0.58 10.4 9.7 2.5 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain UPF0547 PF10571.9 EKX44937.1 - 1.9 8.7 16.7 1.1 9.3 0.6 3.6 3 1 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-C3HC4_2 PF13923.6 EKX44937.1 - 1.9 8.4 14.6 0.88 9.5 8.8 2.8 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) FeS PF04060.13 EKX44937.1 - 2.7 7.7 0.1 2.7 7.7 0.1 2.6 3 0 0 3 3 3 0 Putative Fe-S cluster HypA PF01155.19 EKX44937.1 - 3 7.9 7.1 25 4.9 7.1 2.0 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ribosomal_L37e PF01907.19 EKX44937.1 - 4.2 7.6 15.8 0.68 10.1 4.0 3.0 2 1 1 3 3 3 0 Ribosomal protein L37e zf-C3HC4 PF00097.25 EKX44937.1 - 8.6 6.3 15.1 1.5e+02 2.3 15.6 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-AN1 PF01428.16 EKX44937.1 - 9.3 6.5 16.8 1.5e+02 2.6 12.9 3.0 2 1 0 2 2 2 0 AN1-like Zinc finger LRR_8 PF13855.6 EKX44939.1 - 5.9e-25 86.8 39.9 1.5e-08 34.3 2.5 6.6 2 1 6 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 EKX44939.1 - 6.3e-19 67.8 43.6 2.2e-05 24.7 0.1 9.0 6 3 3 9 9 9 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX44939.1 - 0.0064 16.9 28.5 17 6.5 0.0 10.0 9 2 0 9 9 9 3 Leucine Rich Repeat CREPT PF16566.5 EKX44939.1 - 0.043 14.0 1.0 13 6.0 0.1 3.9 3 2 3 6 6 6 0 Cell-cycle alteration and expression-elevated protein in tumour RsmF_methylt_CI PF17126.5 EKX44939.1 - 0.087 12.9 0.6 11 6.2 0.0 3.8 4 0 0 4 4 4 0 RsmF rRNA methyltransferase first C-terminal domain ZapB PF06005.12 EKX44940.1 - 0.0084 16.5 3.6 0.015 15.7 3.5 1.6 1 1 0 1 1 1 1 Cell division protein ZapB YabA PF06156.13 EKX44940.1 - 0.017 15.7 5.2 0.062 13.9 5.3 1.9 1 1 0 1 1 1 0 Initiation control protein YabA HIP1_clath_bdg PF16515.5 EKX44940.1 - 0.044 14.4 0.6 0.044 14.4 0.6 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 V_ATPase_I PF01496.19 EKX44940.1 - 0.059 11.3 3.5 0.066 11.1 3.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PI_PP_I PF18363.1 EKX44940.1 - 0.069 13.3 1.1 0.11 12.6 1.1 1.3 1 0 0 1 1 1 0 Phosphoinositide phosphatase insertion domain Ank_4 PF13637.6 EKX44941.1 - 6.5e-16 58.5 0.7 4.3e-05 24.0 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX44941.1 - 2.2e-13 50.6 0.0 5.8e-10 39.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX44941.1 - 1.7e-10 40.9 2.0 0.00044 20.5 0.0 3.9 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX44941.1 - 1.6e-09 37.2 0.6 0.58 10.9 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EKX44941.1 - 5.7e-08 32.9 0.1 0.031 14.7 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Pkinase PF00069.25 EKX44942.1 - 6.8e-48 163.3 0.0 7.8e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX44942.1 - 4.5e-30 104.8 0.0 5.5e-30 104.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX44942.1 - 6.5e-08 32.2 0.0 9.7e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EKX44942.1 - 2.4e-07 30.5 0.0 3.7e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 EKX44942.1 - 1.2e-05 24.3 0.0 0.00081 18.3 0.0 2.0 1 1 1 2 2 2 2 Fungal protein kinase APH PF01636.23 EKX44942.1 - 2.1e-05 24.6 0.1 0.0031 17.5 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 EKX44942.1 - 0.0024 17.5 0.0 0.28 10.8 0.0 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EKX44942.1 - 0.0055 16.1 0.0 1.9 7.7 0.0 2.6 1 1 0 2 2 2 2 Kinase-like Ion_trans PF00520.31 EKX44944.1 - 1.8e-40 138.7 8.1 2.4e-40 138.3 8.1 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX44944.1 - 2.5e-14 53.0 3.7 2.5e-14 53.0 3.7 1.9 2 0 0 2 2 2 1 Ion channel BTB_2 PF02214.22 EKX44944.1 - 2.2e-08 34.3 0.0 4.5e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain PKD_channel PF08016.12 EKX44944.1 - 0.00037 19.3 1.5 0.00061 18.6 1.5 1.4 1 1 0 1 1 1 1 Polycystin cation channel zf-RING_2 PF13639.6 EKX44945.1 - 1.9e-06 28.1 0.6 1.9e-06 28.1 0.6 1.9 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EKX44945.1 - 2.6e-06 27.6 1.8 4.3e-06 26.9 1.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EKX44945.1 - 0.00013 21.8 0.3 0.00013 21.8 0.3 1.8 3 0 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX44945.1 - 0.0002 21.2 0.6 0.0002 21.2 0.6 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EKX44945.1 - 0.00036 20.3 0.7 0.00036 20.3 0.7 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EKX44945.1 - 0.0016 18.5 0.2 0.003 17.6 0.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 EKX44945.1 - 0.004 17.3 1.6 0.15 12.3 1.6 2.4 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_11 PF17123.5 EKX44945.1 - 0.016 14.9 0.2 0.04 13.7 0.2 1.7 1 0 0 1 1 1 0 RING-like zinc finger Prok-RING_4 PF14447.6 EKX44945.1 - 0.02 14.8 3.5 0.091 12.6 3.5 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EKX44945.1 - 0.043 13.9 2.6 0.32 11.0 3.1 2.2 1 1 1 2 2 2 0 RING-type zinc-finger Fibrillin_U_N PF18193.1 EKX44945.1 - 0.12 12.5 0.4 0.24 11.6 0.4 1.5 1 0 0 1 1 1 0 Fibrillin 1 unique N-terminal domain zf-C3HC4_3 PF13920.6 EKX44945.1 - 0.13 12.2 0.9 0.63 10.0 0.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 EKX44945.1 - 0.33 11.0 6.9 0.59 10.2 3.3 2.8 2 1 0 2 2 2 0 Zinc-finger zf-C3HC4_4 PF15227.6 EKX44945.1 - 0.4 10.9 3.1 0.33 11.1 0.6 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING U71 PF17474.2 EKX44946.1 - 0.049 13.6 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 Tegument protein UL11 homolog Aa_trans PF01490.18 EKX44947.1 - 3.2e-43 148.0 34.7 3.5e-41 141.3 34.7 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1418 PF07214.12 EKX44947.1 - 7.1 6.6 7.4 3.2 7.7 0.3 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1418) PRELI PF04707.14 EKX44948.1 - 3e-13 49.9 0.3 6.4e-08 32.6 0.1 3.0 1 1 1 2 2 2 2 PRELI-like family DUF2469 PF10611.9 EKX44948.1 - 0.028 15.0 0.0 0.098 13.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2469) H_PPase PF03030.16 EKX44949.1 - 2.9e-218 726.7 38.0 3.5e-218 726.4 38.0 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase CBFD_NFYB_HMF PF00808.23 EKX44950.1 - 2e-07 31.2 0.8 1.5e-06 28.4 0.2 2.3 1 1 1 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAFII28 PF04719.14 EKX44950.1 - 0.0046 17.0 0.2 0.011 15.8 0.2 1.6 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CENP-X PF09415.10 EKX44950.1 - 0.076 13.3 2.6 2.1 8.7 0.2 2.6 2 1 1 3 3 3 0 CENP-S associating Centromere protein X SR-25 PF10500.9 EKX44950.1 - 0.099 12.2 0.8 0.15 11.6 0.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.25 EKX44952.1 - 2.8e-40 138.3 0.0 1.6e-19 70.3 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EKX44952.1 - 4.8e-27 94.9 0.0 1.6e-15 57.1 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EKX44952.1 - 4.4e-06 26.2 0.0 1.1e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Complex1_LYR_2 PF13233.6 EKX44952.1 - 0.19 12.5 0.7 3.3 8.5 0.0 3.0 3 0 0 3 3 3 0 Complex1_LYR-like DUF21 PF01595.20 EKX44953.1 - 8.8e-31 106.9 1.8 1.1e-30 106.6 1.8 1.1 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain Mob_synth_C PF06463.13 EKX44954.1 - 2.7e-39 134.0 0.0 4.2e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 EKX44954.1 - 1.7e-21 77.3 0.0 3e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EKX44954.1 - 1.5e-09 38.2 0.0 3.4e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EKX44954.1 - 0.00019 21.6 0.0 0.00039 20.5 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain PDZ PF00595.24 EKX44955.1 - 3.5e-09 36.9 0.1 0.00025 21.4 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX44955.1 - 2.7e-07 30.8 0.1 0.01 16.1 0.0 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EKX44955.1 - 0.00031 20.5 0.2 0.12 12.2 0.0 3.3 3 0 0 3 3 3 2 PDZ domain Methyltransf_12 PF08242.12 EKX44955.1 - 0.079 13.7 0.0 11 6.8 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain PDZ_2 PF13180.6 EKX44956.1 - 3.9e-06 27.1 0.1 1.9e-05 24.9 0.0 2.2 1 1 1 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 EKX44956.1 - 0.0034 17.3 0.0 0.011 15.7 0.0 1.9 1 0 0 1 1 1 1 Tricorn protease PDZ domain PDZ PF00595.24 EKX44956.1 - 0.0039 17.5 0.1 0.012 15.9 0.1 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX44956.1 - 0.083 12.7 0.4 0.47 10.3 0.4 2.3 1 1 0 1 1 1 0 PDZ domain DUF4972 PF16342.5 EKX44956.1 - 2.3 7.9 12.4 1 9.1 3.4 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4972) Sel1 PF08238.12 EKX44959.1 - 4.3e-68 224.2 35.9 2.5e-09 37.5 1.1 10.9 11 0 0 11 11 11 10 Sel1 repeat TPR_12 PF13424.6 EKX44959.1 - 0.00077 19.7 10.9 1.8 8.9 0.1 6.6 4 3 2 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX44959.1 - 0.0045 17.5 4.7 29 5.6 0.1 5.9 5 1 1 6 6 6 1 Tetratricopeptide repeat DUF5610 PF18433.1 EKX44959.1 - 0.022 15.3 0.4 0.33 11.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5610) Ssl1 PF04056.14 EKX44960.1 - 7.5e-31 107.4 0.0 2.1e-19 70.1 0.0 2.1 2 0 0 2 2 2 2 Ssl1-like C1_4 PF07975.12 EKX44960.1 - 1.7e-05 25.0 8.8 1.7e-05 25.0 8.8 1.9 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 EKX44960.1 - 2.9e-05 24.7 0.0 6.5e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain DZR PF12773.7 EKX44960.1 - 0.0023 17.9 3.9 0.024 14.7 1.5 2.2 1 1 1 2 2 2 2 Double zinc ribbon zinc-ribbons_6 PF07191.12 EKX44960.1 - 0.13 12.3 4.7 0.25 11.4 0.9 2.2 2 0 0 2 2 2 0 zinc-ribbons DUF1263 PF06882.12 EKX44960.1 - 0.15 12.2 0.8 0.62 10.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1263) PHD PF00628.29 EKX44960.1 - 9.2 6.2 7.5 29 4.7 0.0 2.7 2 1 0 2 2 2 0 PHD-finger CPP1-like PF11833.8 EKX44961.1 - 0.17 11.5 1.8 0.21 11.2 0.9 1.6 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like SET PF00856.28 EKX44963.1 - 1.9e-05 25.1 0.7 0.00047 20.6 0.1 2.7 2 1 0 2 2 2 1 SET domain Abhydrolase_1 PF00561.20 EKX44964.1 - 1.6e-09 37.8 0.1 9.5e-07 28.7 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EKX44964.1 - 2.1e-06 27.2 0.1 5.3e-05 22.6 0.0 2.5 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 EKX44964.1 - 3.9e-06 26.9 0.0 6.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein FSH1 PF03959.13 EKX44964.1 - 0.00074 19.2 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EKX44964.1 - 0.004 17.0 0.0 0.011 15.6 0.0 1.6 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EKX44964.1 - 0.006 16.1 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 EKX44964.1 - 0.079 12.7 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 EKX44964.1 - 0.09 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase Methyltransf_11 PF08241.12 EKX44965.1 - 2.9e-12 47.1 0.0 4.6e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX44965.1 - 1.9e-07 31.0 0.0 2.7e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX44965.1 - 3.5e-07 30.8 0.0 9.7e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_29 PF03141.16 EKX44965.1 - 3.8e-06 25.7 0.0 5.3e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 EKX44965.1 - 8.8e-06 26.4 0.0 1.6e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX44965.1 - 0.00015 21.2 0.0 0.00019 20.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EKX44965.1 - 0.00032 20.6 0.0 0.00043 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EKX44965.1 - 0.025 14.4 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Pup PF05639.11 EKX44966.1 - 0.062 14.2 0.4 0.062 14.2 0.4 2.2 2 2 0 2 2 2 0 Pup-like protein Wbp11 PF09429.10 EKX44966.1 - 0.3 11.5 2.1 5.1 7.6 0.3 2.5 2 1 0 2 2 2 0 WW domain binding protein 11 SVIP PF15811.5 EKX44967.1 - 2.2e-07 31.2 2.1 2.2e-07 31.2 2.1 2.1 2 0 0 2 2 2 1 Small VCP/p97-interacting protein TAF8_C PF10406.9 EKX44967.1 - 0.078 13.5 0.2 0.11 13.0 0.2 1.2 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term Bcl-2 PF00452.19 EKX44968.1 - 0.1 13.3 0.8 0.64 10.7 0.2 2.5 2 0 0 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family Pro_isomerase PF00160.21 EKX44969.1 - 2.7e-43 148.0 0.1 4.1e-43 147.4 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 EKX44969.1 - 6.5e-14 51.5 0.0 1.4e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EKX44969.1 - 0.18 11.4 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_1 PF00036.32 EKX44970.1 - 1.9e-07 30.1 1.1 3.5e-07 29.3 1.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 EKX44970.1 - 1.2e-05 24.6 1.6 2e-05 23.9 1.6 1.4 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EKX44970.1 - 2e-05 24.1 0.5 4.1e-05 23.2 0.5 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 EKX44970.1 - 0.00019 21.2 1.0 0.00039 20.2 1.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 EKX44970.1 - 0.0046 17.4 0.3 0.011 16.2 0.3 1.7 1 0 0 1 1 1 1 EF-hand domain pair DUF3368 PF11848.8 EKX44970.1 - 0.083 12.7 0.0 0.98 9.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) DNA_repr_REX1B PF14966.6 EKX44971.1 - 0.038 14.6 0.0 0.16 12.6 0.0 2.0 2 0 0 2 2 2 0 DNA repair REX1-B DUF996 PF06195.13 EKX44971.1 - 0.062 13.6 6.1 0.14 12.4 6.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF996) DUF4446 PF14584.6 EKX44971.1 - 0.11 12.5 0.1 0.32 11.0 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) DUF4199 PF13858.6 EKX44971.1 - 0.41 11.0 5.3 0.12 12.8 1.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) DUF4199 PF13858.6 EKX44972.1 - 0.0032 17.9 1.7 0.0051 17.2 0.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4199) DNA_repr_REX1B PF14966.6 EKX44972.1 - 0.046 14.4 0.0 0.17 12.6 0.0 1.9 1 0 0 1 1 1 0 DNA repair REX1-B DASH_Ask1 PF08655.10 EKX44973.1 - 0.029 14.3 0.1 0.052 13.4 0.1 1.4 1 0 0 1 1 1 0 DASH complex subunit Ask1 DHquinase_II PF01220.19 EKX44974.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Dehydroquinase class II Ion_trans_2 PF07885.16 EKX44975.1 - 1.4e-42 143.5 31.7 1.6e-18 66.4 4.4 3.9 3 1 0 3 3 3 3 Ion channel Ion_trans PF00520.31 EKX44975.1 - 6.6e-12 45.2 13.6 9.4e-08 31.6 0.9 3.2 2 1 1 3 3 3 3 Ion transport protein IRK PF01007.20 EKX44975.1 - 2.3e-06 27.4 7.4 0.0022 17.8 0.6 3.4 3 0 0 3 3 3 2 Inward rectifier potassium channel transmembrane domain Lig_chan PF00060.26 EKX44975.1 - 4.2e-05 23.4 4.9 0.001 18.9 0.4 3.1 3 0 0 3 3 3 1 Ligand-gated ion channel DUF1146 PF06612.11 EKX44975.1 - 0.089 12.9 0.1 0.089 12.9 0.1 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1146) DUF2207 PF09972.9 EKX44975.1 - 3.8 6.2 5.2 0.52 9.0 1.1 1.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) MitMem_reg PF13012.6 EKX44976.1 - 3e-28 98.5 1.1 4.7e-28 97.8 1.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EKX44976.1 - 6.4e-24 84.2 0.1 1.5e-23 83.0 0.0 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Mpv17_PMP22 PF04117.12 EKX44977.1 - 2.3e-08 34.1 0.3 5.8e-08 32.9 0.3 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family PLAC8 PF04749.17 EKX44978.1 - 3.1e-07 31.3 1.5 5.1e-07 30.6 1.5 1.3 1 0 0 1 1 1 1 PLAC8 family ubiquitin PF00240.23 EKX44979.1 - 5.4e-33 112.6 0.5 8.2e-33 112.0 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin family HMG_box PF00505.19 EKX44979.1 - 1.8e-16 60.3 0.2 3.9e-16 59.2 0.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box Rad60-SLD PF11976.8 EKX44979.1 - 5.4e-16 58.2 0.7 9.1e-16 57.5 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like HMG_box_2 PF09011.10 EKX44979.1 - 5.6e-09 36.5 0.4 1.5e-08 35.1 0.4 1.7 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 EKX44979.1 - 1.1e-05 25.2 0.1 2.2e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 CHDNT (NUC034) domain Ubiquitin_2 PF14560.6 EKX44979.1 - 0.00023 21.6 0.1 0.0011 19.4 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 EKX44979.1 - 0.0073 16.9 0.9 0.017 15.7 0.9 1.7 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 EKX44979.1 - 0.0093 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EKX44979.1 - 0.025 14.7 0.0 0.025 14.7 0.0 2.5 2 1 1 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EKX44979.1 - 0.036 14.4 0.1 0.036 14.4 0.1 1.6 2 0 0 2 2 1 0 Ubiquitin-like domain DUF4776 PF16003.5 EKX44979.1 - 0.058 12.4 5.9 0.065 12.2 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Ribosomal_60s PF00428.19 EKX44979.1 - 0.56 10.8 7.4 0.7 10.5 5.5 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ubiquitin_4 PF18036.1 EKX44979.1 - 3.8 7.6 5.4 19 5.4 0.0 2.7 3 0 0 3 3 3 0 Ubiquitin-like domain Stm1_N PF09598.10 EKX44979.1 - 5.4 7.9 15.8 16 6.4 15.8 1.8 1 0 0 1 1 1 0 Stm1 TMEM215 PF15746.5 EKX44980.1 - 0.13 11.7 0.7 0.17 11.3 0.7 1.1 1 0 0 1 1 1 0 TMEM215 family DUF2207 PF09972.9 EKX44981.1 - 0.0098 14.7 0.1 0.016 14.0 0.0 1.3 1 1 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF4404 PF14357.6 EKX44982.1 - 0.0045 17.6 1.2 0.046 14.4 0.5 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4404) Herpes_BTRF1 PF04682.12 EKX44982.1 - 0.0075 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus BTRF1 protein conserved region Takusan PF04822.13 EKX44983.1 - 0.31 11.0 10.8 3.8 7.5 1.4 3.0 2 1 0 2 2 2 0 Takusan SPACA9 PF15120.6 EKX44983.1 - 0.34 10.7 10.3 0.2 11.5 3.8 2.5 1 1 2 3 3 3 0 Sperm acrosome-associated protein 9 IL31 PF15209.6 EKX44983.1 - 0.37 10.6 0.1 0.37 10.6 0.1 2.3 3 0 0 3 3 3 0 Interleukin 31 DUF3211 PF11485.8 EKX44983.1 - 0.58 10.4 3.7 1.5 9.1 3.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3211) DUF948 PF06103.11 EKX44983.1 - 0.73 10.1 3.8 9.8 6.5 0.1 3.5 2 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) WBP-1 PF11669.8 EKX44985.1 - 0.11 13.1 4.9 0.057 14.1 2.8 1.7 2 0 0 2 2 2 0 WW domain-binding protein 1 CH_2 PF06294.11 EKX44986.1 - 1.2e-35 121.5 0.1 2.8e-35 120.3 0.1 1.7 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 EKX44986.1 - 3.4e-16 58.9 0.0 1e-15 57.3 0.0 1.9 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.31 EKX44986.1 - 0.066 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Calponin homology (CH) domain Cep57_CLD_2 PF14197.6 EKX44986.1 - 1.9 8.6 7.5 0.42 10.7 3.1 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 TPR_12 PF13424.6 EKX44989.1 - 0.0044 17.3 0.1 0.01 16.1 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat SPO22 PF08631.10 EKX44989.1 - 0.015 14.8 0.3 0.022 14.3 0.3 1.2 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like HemY_N PF07219.13 EKX44989.1 - 0.12 12.6 0.3 0.12 12.6 0.3 3.1 5 0 0 5 5 5 0 HemY protein N-terminus EXOSC1 PF10447.9 EKX44989.1 - 0.2 12.3 1.0 0.48 11.0 1.0 1.6 1 0 0 1 1 1 0 Exosome component EXOSC1/CSL4 AIM3 PF17096.5 EKX44989.1 - 1.1 10.2 10.9 0.055 14.4 4.4 2.2 2 2 0 2 2 2 0 Altered inheritance of mitochondria protein 3 2OG-FeII_Oxy PF03171.20 EKX44990.1 - 4.4e-08 33.5 0.0 8.4e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily VanZ PF04892.12 EKX44991.1 - 0.003 18.2 2.7 0.0041 17.8 2.7 1.3 1 0 0 1 1 1 1 VanZ like family TcpE PF12648.7 EKX44991.1 - 0.19 12.3 13.7 0.32 11.5 13.7 1.4 1 0 0 1 1 1 0 TcpE family DUF898 PF05987.13 EKX44991.1 - 5.5 5.9 16.0 6.9 5.6 16.0 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF3043 PF11241.8 EKX44991.1 - 8.2 6.4 17.1 11 6.1 17.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) AphA_like PF14557.6 EKX44992.1 - 0.03 14.0 0.1 0.035 13.8 0.1 1.1 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator Rad60-SLD_2 PF13881.6 EKX44993.1 - 1.1e-18 67.4 0.1 1.2e-18 67.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EKX44993.1 - 8.7e-05 22.2 0.2 0.00017 21.3 0.2 1.6 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_5 PF18037.1 EKX44993.1 - 0.0027 18.0 0.1 0.0035 17.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 EKX44993.1 - 0.014 15.9 0.0 0.016 15.7 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain MRP-L47 PF06984.13 EKX44993.1 - 0.055 13.6 0.0 0.067 13.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Rad60-SLD PF11976.8 EKX44993.1 - 0.057 13.3 0.2 0.11 12.3 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Methyltransf_16 PF10294.9 EKX44994.1 - 8e-36 123.4 0.0 1.2e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EKX44994.1 - 4e-05 23.5 0.0 5.8e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX44994.1 - 0.0019 18.0 0.0 0.0036 17.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EKX44994.1 - 0.0038 16.9 0.0 0.0065 16.1 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 EKX44994.1 - 0.02 14.4 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 EKX44994.1 - 0.033 13.6 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EKX44994.1 - 0.038 14.7 0.1 0.079 13.7 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain COMM_domain PF07258.14 EKX44995.1 - 2.8e-12 46.6 0.0 6.9e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 COMM domain CDC45 PF02724.14 EKX44996.1 - 0.074 11.3 14.5 0.1 10.8 14.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 EKX44996.1 - 0.16 11.4 18.9 0.21 11.0 18.9 1.1 1 0 0 1 1 1 0 SDA1 SAPS PF04499.15 EKX44996.1 - 0.24 10.1 5.9 0.33 9.7 5.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 EKX44996.1 - 0.41 8.8 18.4 0.54 8.4 18.4 1.1 1 0 0 1 1 1 0 Nop14-like family Med21 PF11221.8 EKX44997.1 - 6.1e-09 36.3 1.1 3.6e-07 30.5 1.1 2.2 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Ntox35 PF15534.6 EKX44999.1 - 0.00029 21.2 0.0 0.00059 20.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial toxin 35 ANAPC4_WD40 PF12894.7 EKX44999.1 - 0.027 14.7 0.0 1.4 9.3 0.0 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain VEG PF06257.11 EKX44999.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Biofilm formation stimulator VEG DUF406 PF04175.12 EKX45001.1 - 0.49 10.9 4.7 0.49 10.9 0.4 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF406) DUF1168 PF06658.12 EKX45003.1 - 1.1e-20 73.9 25.3 1.8e-20 73.1 25.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Borrelia_orfA PF02414.15 EKX45003.1 - 0.00092 19.0 3.2 0.0011 18.8 3.2 1.2 1 0 0 1 1 1 1 Borrelia ORF-A Hid1 PF12722.7 EKX45003.1 - 0.03 12.5 7.6 0.04 12.1 7.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Draxin PF15550.6 EKX45003.1 - 0.032 14.1 9.4 0.036 14.0 9.4 1.1 1 0 0 1 1 1 0 Draxin PEHE PF15275.6 EKX45003.1 - 0.71 10.5 11.8 1 10.0 11.8 1.5 1 1 0 1 1 1 0 PEHE domain PNISR PF15996.5 EKX45003.1 - 1 9.6 17.6 0.18 12.0 12.3 2.0 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR DUF3340 PF11818.8 EKX45003.1 - 2.1 8.5 19.6 0.24 11.5 14.6 1.8 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) PIEZO PF15917.5 EKX45003.1 - 6.3 6.2 12.0 2.4 7.6 9.6 1.5 1 1 0 1 1 1 0 Piezo LysM PF01476.20 EKX45005.1 - 3.8e-06 26.9 0.0 0.012 15.6 0.0 2.7 2 0 0 2 2 2 2 LysM domain Ion_trans PF00520.31 EKX45006.1 - 2.6e-41 141.5 30.2 4.2e-41 140.8 30.2 1.3 1 0 0 1 1 1 1 Ion transport protein CCDC-167 PF15188.6 EKX45006.1 - 0.68 10.3 8.1 8.9 6.7 0.1 3.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Exonuc_VII_L PF02601.15 EKX45006.1 - 2.1 7.9 11.5 0.32 10.5 7.6 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit TPR_17 PF13431.6 EKX45007.1 - 1e-12 47.5 6.6 0.0002 21.5 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EKX45007.1 - 1.4e-12 48.0 6.8 2.1e-05 24.9 0.1 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX45007.1 - 9.5e-12 44.7 2.8 0.0051 17.5 0.0 5.8 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX45007.1 - 1.8e-07 31.4 3.7 0.039 14.2 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX45007.1 - 1e-05 25.1 9.6 0.38 10.5 0.0 5.5 6 1 1 7 7 7 3 TPR repeat TPR_2 PF07719.17 EKX45007.1 - 6.7e-05 22.7 9.1 1.3 9.3 0.0 5.7 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 EKX45007.1 - 0.00013 21.3 3.9 0.066 12.4 0.2 3.6 2 2 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX45007.1 - 0.00015 21.9 0.7 0.016 15.4 0.2 2.9 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EKX45007.1 - 0.00017 21.2 9.2 0.8 9.6 0.1 5.8 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX45007.1 - 0.00025 21.0 6.6 2.6 8.5 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX45007.1 - 0.0066 16.6 0.5 3.1 8.0 0.0 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX45007.1 - 0.0067 16.4 3.7 0.38 10.9 0.0 4.7 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX45007.1 - 0.015 15.9 3.4 17 6.1 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX45007.1 - 0.019 15.1 1.7 14 5.9 0.1 4.0 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Mhr1 PF12829.7 EKX45007.1 - 0.09 12.9 0.1 0.27 11.3 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulation of mitochondrial recombination TPR_6 PF13174.6 EKX45007.1 - 0.32 11.7 7.3 12 6.8 0.1 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX45007.1 - 2.3 8.2 9.9 6.8 6.7 0.1 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat LCM PF04072.14 EKX45008.1 - 8.3e-15 55.2 0.0 1.2e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Peptidase_M26_C PF07580.14 EKX45008.1 - 0.21 10.1 0.0 0.27 9.7 0.0 1.0 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region HECT PF00632.25 EKX45009.1 - 7.6e-55 186.6 0.0 8.3e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PDZ PF00595.24 EKX45010.1 - 2.1e-09 37.6 3.7 7.8e-09 35.8 0.3 3.0 3 1 0 3 3 3 1 PDZ domain PDZ_2 PF13180.6 EKX45010.1 - 3.8e-06 27.1 0.2 2.3e-05 24.6 0.1 2.3 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EKX45010.1 - 1.9e-05 24.4 0.2 0.00017 21.4 0.1 2.6 3 0 0 3 3 3 1 PDZ domain Lebercilin PF15619.6 EKX45010.1 - 0.0043 16.7 7.1 0.0043 16.7 7.1 3.7 3 1 0 3 3 3 2 Ciliary protein causing Leber congenital amaurosis disease ATG16 PF08614.11 EKX45010.1 - 0.018 15.3 12.7 0.018 15.3 12.7 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 EKX45010.1 - 0.071 13.3 25.3 0.27 11.4 4.6 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Imm27 PF15590.6 EKX45010.1 - 0.19 11.5 0.6 27 4.6 0.1 2.6 1 1 1 2 2 2 0 Immunity protein 27 Laminin_II PF06009.12 EKX45010.1 - 0.34 10.9 26.4 0.85 9.6 1.6 3.3 1 1 1 3 3 3 0 Laminin Domain II DUF4634 PF15465.6 EKX45010.1 - 1.2 9.4 3.9 1.4 9.3 0.6 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4634) TSC22 PF01166.18 EKX45010.1 - 1.6 9.1 8.0 0.53 10.6 0.3 3.4 3 0 0 3 3 3 0 TSC-22/dip/bun family Tropomyosin_1 PF12718.7 EKX45010.1 - 2.1 8.5 39.7 0.41 10.8 6.7 4.0 1 1 3 4 4 4 0 Tropomyosin like APG6_N PF17675.1 EKX45010.1 - 2.2 8.8 40.6 0.92 10.0 7.1 3.2 2 1 1 3 3 3 0 Apg6 coiled-coil region COG5 PF10392.9 EKX45010.1 - 2.8 8.1 16.4 0.65 10.2 5.3 3.3 2 1 1 3 3 3 0 Golgi transport complex subunit 5 Bcr-Abl_Oligo PF09036.10 EKX45010.1 - 8 6.5 6.9 7.6 6.6 1.4 2.9 2 1 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain CTD_bind PF04818.13 EKX45011.1 - 9.8e-10 39.1 0.9 1.8e-09 38.3 0.6 1.7 2 0 0 2 2 2 1 RNA polymerase II-binding domain. VHS PF00790.19 EKX45011.1 - 0.023 14.6 2.1 0.037 13.9 2.1 1.4 1 1 0 1 1 1 0 VHS domain CSN7a_helixI PF18392.1 EKX45011.1 - 0.16 11.9 2.4 1.6 8.7 0.2 2.6 2 1 0 2 2 2 0 COP9 signalosome complex subunit 7a helix I domain Glyco_transf_41 PF13844.6 EKX45013.1 - 3.2e-06 25.9 0.0 0.012 14.1 0.0 2.7 3 0 0 3 3 3 2 Glycosyl transferase family 41 TPR_14 PF13428.6 EKX45013.1 - 1.3e-05 25.6 6.5 0.59 11.1 0.3 4.9 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX45013.1 - 0.0001 21.9 0.0 0.28 10.9 0.0 3.5 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.17 EKX45013.1 - 0.00012 22.0 4.1 13 6.2 0.1 4.9 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX45013.1 - 0.0019 18.8 7.7 0.0049 17.5 2.9 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX45013.1 - 0.02 15.1 2.0 27 5.3 0.0 4.6 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 EKX45013.1 - 0.15 12.5 0.3 4.3 7.9 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EKX45013.1 - 0.2 11.6 0.4 39 4.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX45013.1 - 0.25 11.6 6.8 3.7 7.8 0.1 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EKX45013.1 - 0.52 10.9 4.4 30 5.2 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX45013.1 - 1.9 8.8 4.9 7.1 7.0 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Neuralized PF07177.12 EKX45014.1 - 0.002 18.2 0.0 0.0023 17.9 0.0 1.2 1 0 0 1 1 1 1 Neuralized SPRY PF00622.28 EKX45014.1 - 0.0057 16.8 0.0 0.011 15.9 0.0 1.5 1 1 0 1 1 1 1 SPRY domain Roughex PF06020.11 EKX45014.1 - 0.56 9.3 2.5 0.75 8.8 2.5 1.1 1 0 0 1 1 1 0 Drosophila roughex protein C2 PF00168.30 EKX45015.1 - 7.6e-07 29.4 0.0 2.6e-06 27.6 0.0 2.0 1 0 0 1 1 1 1 C2 domain CC2D2AN-C2 PF15625.6 EKX45015.1 - 3.6e-05 23.6 0.1 0.00015 21.5 0.1 2.1 2 0 0 2 2 2 1 CC2D2A N-terminal C2 domain DUF692 PF05114.13 EKX45016.1 - 0.0031 16.8 0.1 0.0039 16.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF692) Med11 PF10280.9 EKX45016.1 - 0.012 16.1 0.1 0.014 15.8 0.1 1.4 1 1 0 1 1 1 0 Mediator complex protein DUF3629 PF12302.8 EKX45016.1 - 0.11 11.9 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) N-glycanase_C PF09113.10 EKX45017.1 - 9.9e-28 96.6 0.1 5.2e-27 94.3 0.1 2.1 2 0 0 2 2 2 1 Peptide-N-glycosidase F, C terminal PA PF02225.22 EKX45017.1 - 1.4e-11 44.2 0.0 3.1e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 PA domain N-glycanase_N PF09112.10 EKX45017.1 - 6.3e-05 22.9 0.0 0.00019 21.3 0.0 1.8 1 1 0 1 1 1 1 Peptide-N-glycosidase F, N terminal PDZ PF00595.24 EKX45018.1 - 8.1e-07 29.3 0.1 1.6e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX45018.1 - 1.1e-05 25.1 0.0 1.8e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX45018.1 - 0.00014 22.1 0.0 0.00029 21.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Nudix_N_2 PF14803.6 EKX45018.1 - 0.19 11.7 0.5 0.84 9.6 0.3 2.1 2 0 0 2 2 2 0 Nudix N-terminal WD40 PF00400.32 EKX45019.1 - 2.2e-59 196.0 19.8 1.5e-11 44.7 0.1 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX45019.1 - 1.3e-30 105.5 6.8 2.8e-08 34.0 0.0 5.9 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX45019.1 - 5.6e-17 61.7 0.3 0.0012 17.9 0.0 5.7 1 1 5 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EKX45019.1 - 2.8e-15 56.7 0.8 4e-07 30.1 0.0 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EKX45019.1 - 1.6e-12 47.0 8.4 0.11 12.4 0.1 5.8 6 0 0 6 6 6 4 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 EKX45019.1 - 6.2e-09 36.0 11.4 0.007 16.2 1.6 3.4 1 1 2 3 3 3 3 Lipoprotein LpqB beta-propeller domain DPPIV_N PF00930.21 EKX45019.1 - 6.5e-05 21.8 9.9 1 8.0 0.3 5.3 2 2 0 5 5 5 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region IKI3 PF04762.12 EKX45019.1 - 9.9e-05 20.6 9.4 0.0073 14.4 0.9 3.6 1 1 2 3 3 3 2 IKI3 family Nbas_N PF15492.6 EKX45019.1 - 0.00026 20.4 5.9 0.8 9.0 0.1 4.4 1 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 EKX45019.1 - 0.0011 17.7 7.1 0.29 9.7 0.4 3.6 2 2 2 4 4 4 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.14 EKX45019.1 - 0.0023 17.0 2.1 0.19 10.7 0.1 3.3 1 1 2 3 3 3 1 Coatomer WD associated region Ret2_MD PF18528.1 EKX45019.1 - 0.0085 16.5 0.0 12 6.3 0.0 3.6 3 1 1 4 4 4 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Proteasome_A_N PF10584.9 EKX45019.1 - 0.03 14.0 1.6 63 3.4 0.0 4.4 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Nucleoporin_N PF08801.11 EKX45019.1 - 0.096 11.4 5.2 0.81 8.4 0.1 3.0 2 1 1 3 3 3 0 Nup133 N terminal like WD40_like PF17005.5 EKX45019.1 - 0.12 11.7 0.0 9.6 5.4 0.0 3.3 2 2 2 4 4 4 0 WD40-like domain DUF5570 PF17731.1 EKX45019.1 - 0.2 11.8 14.7 1.5 8.9 0.1 4.1 1 1 2 4 4 4 0 Family of unknown function (DUF5570) GCV_T_C PF08669.11 EKX45019.1 - 0.24 11.3 1.3 5.2 7.1 0.0 3.5 2 2 2 4 4 4 0 Glycine cleavage T-protein C-terminal barrel domain CN_hydrolase PF00795.22 EKX45019.1 - 0.67 9.2 3.7 2.6 7.3 0.1 3.1 3 1 1 4 4 4 0 Carbon-nitrogen hydrolase GPI-anchored PF10342.9 EKX45019.1 - 2.7 8.8 10.9 3.9 8.3 0.3 3.2 3 1 0 3 3 3 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family EF-hand_5 PF13202.6 EKX45020.1 - 5.6e-14 50.9 3.0 0.0073 15.8 0.8 4.7 4 0 0 4 4 4 4 EF hand EF-hand_1 PF00036.32 EKX45020.1 - 2.6e-13 48.5 4.7 0.013 15.0 0.0 5.2 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 EKX45020.1 - 1.7e-11 44.4 3.2 0.22 12.0 0.0 4.8 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EKX45020.1 - 1e-10 40.6 4.6 0.13 12.2 0.0 5.7 6 0 0 6 6 6 4 EF-hand domain SAM_2 PF07647.17 EKX45020.1 - 4.2e-06 26.8 0.0 0.02 15.0 0.0 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) EF-hand_8 PF13833.6 EKX45020.1 - 0.0001 22.1 0.3 2.1 8.3 0.0 4.5 3 1 1 4 4 4 1 EF-hand domain pair FYVE PF01363.21 EKX45020.1 - 0.018 15.2 4.4 0.044 13.9 4.4 1.6 1 0 0 1 1 1 0 FYVE zinc finger zf-AN1 PF01428.16 EKX45020.1 - 0.055 13.7 14.0 0.63 10.2 14.0 2.2 1 1 1 2 2 2 0 AN1-like Zinc finger IBR PF01485.21 EKX45020.1 - 0.49 10.7 5.9 1.2 9.4 5.9 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-HIT PF04438.16 EKX45020.1 - 2.3 8.1 8.4 5.6 6.9 0.8 2.4 2 0 0 2 2 2 0 HIT zinc finger RCC1 PF00415.18 EKX45021.1 - 2.5e-48 162.5 9.4 5.7e-14 52.5 0.2 6.1 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX45021.1 - 2e-26 91.2 28.0 1.8e-08 34.0 0.6 5.4 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat zf-C2H2_jaz PF12171.8 EKX45023.1 - 0.017 15.4 0.5 0.058 13.7 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EKX45023.1 - 0.018 15.9 4.3 0.029 15.2 0.4 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EKX45023.1 - 0.055 13.5 0.3 0.055 13.5 0.3 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 EKX45023.1 - 0.059 13.3 0.3 0.15 12.0 0.3 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 EKX45023.1 - 0.19 12.3 0.3 0.19 12.3 0.3 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf_ZIC PF18366.1 EKX45023.1 - 0.36 11.0 1.0 1.2 9.3 0.1 2.2 2 0 0 2 2 2 0 Zic proteins zinc finger domain zf-DNL PF05180.12 EKX45024.1 - 7.4e-19 67.5 0.5 1.9e-18 66.2 0.5 1.7 1 1 0 1 1 1 1 DNL zinc finger AAA_32 PF13654.6 EKX45024.1 - 0.032 13.0 0.0 0.042 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain ATG27 PF09451.10 EKX45024.1 - 0.038 13.9 0.1 0.046 13.6 0.1 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 PhoLip_ATPase_C PF16212.5 EKX45026.1 - 3.6e-14 53.1 4.0 8.1e-14 52.0 4.0 1.6 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EKX45026.1 - 7.5e-12 44.8 0.2 1.3e-11 44.0 0.2 1.4 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EKX45026.1 - 1.9e-09 37.5 0.0 4.4e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EKX45026.1 - 3.9e-06 27.3 0.5 0.0016 18.7 0.1 3.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EKX45026.1 - 6.1e-06 25.9 0.0 2.8e-05 23.7 0.0 2.1 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EKX45026.1 - 0.016 15.0 0.0 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF4611 PF15387.6 EKX45027.1 - 0.078 13.2 3.5 0.11 12.7 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) F5_F8_type_C PF00754.25 EKX45028.1 - 0.013 15.6 0.0 0.26 11.4 0.0 2.4 2 0 0 2 2 2 0 F5/8 type C domain PhyH PF05721.13 EKX45029.1 - 1.1e-17 65.0 0.1 1.8e-17 64.4 0.1 1.3 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) ProSAAS PF07259.12 EKX45029.1 - 0.025 14.6 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 ProSAAS precursor TPR_MLP1_2 PF07926.12 EKX45030.1 - 0.001 19.2 13.6 0.001 19.2 13.6 4.1 2 1 1 3 3 3 1 TPR/MLP1/MLP2-like protein DUF4472 PF14739.6 EKX45030.1 - 0.0039 17.9 4.3 0.0039 17.9 4.3 5.6 3 1 3 6 6 6 1 Domain of unknown function (DUF4472) DUF3105 PF11303.8 EKX45030.1 - 0.081 13.1 0.1 0.87 9.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3105) Arm PF00514.23 EKX45031.1 - 5.4e-10 39.0 3.8 0.0011 18.9 0.0 5.9 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EKX45031.1 - 1.4e-08 34.7 1.3 0.00057 19.9 0.1 4.2 2 1 2 4 4 4 3 Spinocerebellar ataxia type 10 protein domain ENTH PF01417.20 EKX45031.1 - 0.97 9.5 3.4 1.2 9.2 0.8 2.3 2 0 0 2 2 2 0 ENTH domain Glyoxalase PF00903.25 EKX45032.1 - 1.3e-08 35.1 0.1 2.8e-08 34.0 0.1 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EKX45032.1 - 0.029 15.1 0.0 0.039 14.7 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain MRP_L53 PF10780.9 EKX45035.1 - 2.1e-06 27.8 0.1 3.7e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 SPRY PF00622.28 EKX45037.1 - 9.9e-09 35.3 0.0 1.8e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Hemopexin PF00045.19 EKX45037.1 - 0.15 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Hemopexin EF-hand_7 PF13499.6 EKX45040.1 - 4.6e-16 59.0 2.7 3.8e-09 36.9 0.7 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX45040.1 - 3.2e-11 42.2 2.1 0.00023 20.8 0.1 3.6 4 0 0 4 4 3 3 EF-hand domain EF-hand_8 PF13833.6 EKX45040.1 - 9.1e-09 35.0 4.6 0.0017 18.1 0.0 3.7 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX45040.1 - 5.9e-08 31.7 5.0 0.003 17.0 0.1 4.9 4 1 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 EKX45040.1 - 0.00026 21.2 0.3 0.29 11.5 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain Nop14 PF04147.12 EKX45040.1 - 0.16 10.1 10.1 0.21 9.8 10.1 1.2 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 EKX45040.1 - 1.7 7.1 4.6 2.2 6.7 4.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 EKX45040.1 - 1.8 6.8 5.9 2.5 6.3 5.9 1.2 1 0 0 1 1 1 0 CDC45-like protein PGA2 PF07543.12 EKX45040.1 - 1.8 8.5 12.2 4.1 7.4 12.2 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 DNA_pol_phi PF04931.13 EKX45040.1 - 1.9 6.5 15.3 2.5 6.1 15.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi ORC_WH_C PF18137.1 EKX45040.1 - 3.5 7.7 8.0 7.5 6.6 8.0 1.5 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal RNA_pol_3_Rpc31 PF11705.8 EKX45040.1 - 5 7.3 18.2 0.084 13.1 10.9 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Tim54 PF11711.8 EKX45040.1 - 8.4 5.1 8.6 12 4.6 8.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NOA36 PF06524.12 EKX45040.1 - 8.9 5.5 11.1 13 5.0 11.1 1.2 1 0 0 1 1 1 0 NOA36 protein WD40 PF00400.32 EKX45042.1 - 2.1e-21 75.8 11.9 1.4e-05 25.7 0.3 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat BBS2_Mid PF14783.6 EKX45042.1 - 0.012 15.6 0.0 4.3 7.4 0.0 2.9 1 1 2 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Collagen PF01391.18 EKX45043.1 - 3.2e-06 26.8 13.4 5.8e-06 26.0 13.4 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) PDZ PF00595.24 EKX45046.1 - 5e-08 33.2 0.3 7.3e-08 32.7 0.3 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX45046.1 - 5.5e-08 32.5 1.1 8.7e-08 31.9 1.1 1.3 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX45046.1 - 6.4e-07 29.3 0.3 9.5e-07 28.7 0.3 1.3 1 0 0 1 1 1 1 Tricorn protease PDZ domain PDZ_2 PF13180.6 EKX45046.1 - 0.00022 21.5 1.0 0.00031 21.0 1.0 1.2 1 0 0 1 1 1 1 PDZ domain Opi1 PF08618.10 EKX45047.1 - 0.45 9.7 2.9 0.54 9.4 2.1 1.5 1 1 1 2 2 2 0 Transcription factor Opi1 CobT PF06213.12 EKX45048.1 - 0.025 14.0 5.0 0.044 13.2 5.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Malic_M PF03949.15 EKX45048.1 - 0.55 9.5 2.1 0.99 8.6 0.5 1.9 1 1 1 2 2 2 0 Malic enzyme, NAD binding domain Ion_trans PF00520.31 EKX45049.1 - 3.3e-34 118.2 6.1 4.6e-34 117.8 6.1 1.1 1 0 0 1 1 1 1 Ion transport protein EF-hand_6 PF13405.6 EKX45049.1 - 3e-06 26.7 0.2 5.7e-05 22.7 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EKX45049.1 - 0.00021 20.6 0.1 0.00021 20.6 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EKX45049.1 - 0.00067 20.1 3.7 0.023 15.1 0.3 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX45049.1 - 0.0017 17.7 0.2 0.0017 17.7 0.2 2.2 2 0 0 2 2 2 1 EF hand PH PF00169.29 EKX45049.1 - 0.0056 17.2 0.0 0.015 15.8 0.0 1.8 1 1 0 1 1 1 1 PH domain EF-hand_8 PF13833.6 EKX45049.1 - 0.0066 16.3 1.7 0.012 15.5 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair PKD_channel PF08016.12 EKX45049.1 - 0.01 14.5 12.9 0.27 9.9 6.0 2.5 2 1 0 2 2 2 0 Polycystin cation channel CAP_N PF01213.19 EKX45049.1 - 0.57 9.6 9.6 1.1 8.7 9.6 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 EKX45049.1 - 0.74 9.8 7.3 1.8 8.6 7.3 1.7 1 0 0 1 1 1 0 Mitochondrial fission regulator RR_TM4-6 PF06459.12 EKX45049.1 - 2.9 7.6 11.0 6.3 6.5 11.0 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 VIR_N PF15912.5 EKX45049.1 - 5.7 6.5 16.5 10 5.6 16.5 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal TPT PF03151.16 EKX45050.1 - 7.3e-61 206.0 10.9 8.8e-61 205.8 10.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EKX45050.1 - 4.2e-10 39.9 19.5 4.3e-05 23.7 7.3 2.5 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EKX45050.1 - 0.0037 16.5 6.6 0.0057 15.9 6.6 1.4 1 1 0 1 1 1 1 UAA transporter family DUF4231 PF14015.6 EKX45050.1 - 0.12 12.8 0.1 0.12 12.8 0.1 3.6 2 1 0 3 3 3 0 Protein of unknown function (DUF4231) ANAPC15 PF15243.6 EKX45051.1 - 6.9e-06 26.4 3.0 8.3e-06 26.1 3.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 15 DUF1292 PF06949.11 EKX45051.1 - 0.23 12.4 4.3 0.44 11.5 4.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1292) ClpS PF02617.17 EKX45052.1 - 6.2e-17 61.2 0.1 9.4e-17 60.6 0.1 1.3 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS GP38 PF05268.11 EKX45052.1 - 0.0039 16.9 2.3 0.0052 16.5 2.3 1.1 1 0 0 1 1 1 1 Phage tail fibre adhesin Gp38 Imm44 PF15571.6 EKX45052.1 - 0.19 12.0 0.1 0.27 11.5 0.1 1.2 1 0 0 1 1 1 0 Immunity protein 44 Ion_trans PF00520.31 EKX45053.1 - 6.2e-15 55.1 18.1 9.8e-15 54.4 18.1 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 EKX45053.1 - 2.9e-09 36.9 0.0 8.3e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PH PF00169.29 EKX45053.1 - 4.7e-08 33.5 0.0 1.2e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 PH domain Ion_trans_2 PF07885.16 EKX45053.1 - 4.5e-06 26.5 5.7 4.5e-06 26.5 5.7 2.5 2 1 0 2 2 2 1 Ion channel PH_9 PF15410.6 EKX45053.1 - 0.0039 17.6 0.0 0.013 15.8 0.0 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 EKX45053.1 - 0.023 15.1 0.1 0.18 12.3 0.0 2.5 3 0 0 3 3 3 0 Pleckstrin homology domain MPM1 PF17234.2 EKX45056.1 - 10 6.4 12.4 1.9 8.7 6.6 2.4 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 eIF2A PF08662.11 EKX45057.1 - 5.6e-71 238.4 0.0 3.1e-69 232.7 0.0 2.6 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A AAA_12 PF13087.6 EKX45057.1 - 1.6 8.3 5.5 2.5 7.6 5.5 1.3 1 0 0 1 1 1 0 AAA domain PKD_channel PF08016.12 EKX45058.1 - 1.1e-47 162.7 10.3 1.1e-47 162.7 10.3 2.6 2 1 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 EKX45058.1 - 9.9e-15 54.4 19.7 9.9e-15 54.4 19.7 2.1 2 0 0 2 2 2 1 Ion transport protein Methyltransf_25 PF13649.6 EKX45060.1 - 0.00013 22.6 0.0 0.025 15.3 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX45060.1 - 0.0009 19.1 0.0 0.061 13.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX45060.1 - 0.0065 17.1 0.0 0.77 10.4 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX45060.1 - 0.014 14.8 0.0 1.9 7.8 0.0 3.0 2 1 0 3 3 3 0 ubiE/COQ5 methyltransferase family Perilipin PF03036.16 EKX45060.1 - 0.018 14.1 1.1 0.038 13.0 0.6 1.7 1 1 1 2 2 2 0 Perilipin family Methyltransf_12 PF08242.12 EKX45060.1 - 0.021 15.6 0.0 1.9 9.3 0.0 2.6 1 1 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 EKX45060.1 - 0.024 14.5 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_M75 PF09375.10 EKX45060.1 - 0.11 12.0 0.9 0.2 11.1 0.9 1.4 1 0 0 1 1 1 0 Imelysin NAD_kinase PF01513.21 EKX45061.1 - 3.7e-14 52.6 0.0 5.3e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase TnpB_IS66 PF05717.13 EKX45061.1 - 0.051 13.5 0.0 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 IS66 Orf2 like protein DAGK_cat PF00781.24 EKX45061.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain TraG_N PF07916.11 EKX45062.1 - 0.0037 16.2 2.4 0.0037 16.2 2.4 1.5 2 0 0 2 2 2 1 TraG-like protein, N-terminal region DUF1218 PF06749.12 EKX45062.1 - 3.9 8.1 11.5 3.3 8.3 4.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) DTW PF03942.15 EKX45066.1 - 8.3e-38 130.1 1.1 2.2e-37 128.7 1.1 1.7 1 1 0 1 1 1 1 DTW domain Memo PF01875.17 EKX45067.1 - 2.4e-82 276.2 0.0 2.7e-82 276.0 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Phytochelatin PF05023.14 EKX45067.1 - 0.035 13.3 0.3 0.09 12.0 0.2 1.7 1 1 1 2 2 2 0 Phytochelatin synthase Glycos_transf_1 PF00534.20 EKX45068.1 - 3.2e-39 134.2 0.0 5.1e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EKX45068.1 - 2.2e-29 102.6 0.0 4.2e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EKX45068.1 - 7.5e-29 100.9 0.1 4e-28 98.5 0.1 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EKX45068.1 - 1.9e-20 73.9 0.0 4e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 EKX45068.1 - 9.8e-13 48.4 0.1 5.4e-05 23.0 0.1 2.4 1 1 1 2 2 2 2 Starch synthase catalytic domain Glyco_trans_1_2 PF13524.6 EKX45068.1 - 3.7e-08 33.6 0.0 7.1e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 EKX45068.1 - 2.2e-05 24.5 0.0 5.9e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glycogen_syn PF05693.13 EKX45068.1 - 0.031 12.8 0.0 0.058 12.0 0.0 1.3 1 0 0 1 1 1 0 Glycogen synthase Eno-Rase_FAD_bd PF07055.12 EKX45068.1 - 0.08 13.4 0.2 0.17 12.3 0.2 1.5 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain Ank_2 PF12796.7 EKX45070.1 - 2.3e-21 76.2 6.0 6.6e-10 39.5 0.2 1.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX45070.1 - 9.9e-12 44.9 1.3 1.2e-09 38.2 0.3 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX45070.1 - 1.7e-09 37.1 0.5 0.0002 21.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EKX45070.1 - 2.5e-09 37.5 0.1 1e-08 35.5 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX45070.1 - 2.9e-08 33.8 1.5 0.004 17.5 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat PTPS PF01242.19 EKX45072.1 - 1.9e-17 63.4 0.0 2.5e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase Acyltransferase PF01553.21 EKX45073.1 - 3.3e-09 36.5 0.0 2.9e-05 23.7 0.0 2.5 2 0 0 2 2 2 2 Acyltransferase FtsK_4TM PF13491.6 EKX45073.1 - 0.029 14.1 0.7 0.029 14.1 0.7 2.9 3 1 0 3 3 3 0 4TM region of DNA translocase FtsK/SpoIIIE RCC1 PF00415.18 EKX45074.1 - 1.5e-14 54.3 0.2 4.4e-11 43.2 0.0 2.0 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX45074.1 - 9.7e-11 41.2 1.9 7.1e-08 32.0 0.3 2.1 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat Mcl1_mid PF12341.8 EKX45074.1 - 0.074 12.4 0.0 0.074 12.4 0.0 1.0 1 0 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region FKBP_C PF00254.28 EKX45077.1 - 1.5e-17 63.7 0.0 1.8e-14 53.8 0.0 2.8 3 0 0 3 3 3 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 EKX45077.1 - 2.6e-07 30.2 6.2 0.0095 15.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX45077.1 - 1.8e-06 27.6 5.7 0.0019 18.1 2.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX45077.1 - 5.1e-06 26.3 2.0 0.023 14.9 1.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX45077.1 - 0.0036 17.3 0.7 1.9 8.6 0.1 2.5 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 EKX45077.1 - 0.01 16.1 1.7 0.049 13.9 0.5 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX45077.1 - 0.065 13.6 0.2 32 5.2 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX45077.1 - 0.077 13.7 0.2 57 4.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX45077.1 - 0.65 11.0 2.5 2.9 8.9 0.5 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX45077.1 - 0.83 10.2 9.0 6.2 7.4 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat SSF PF00474.17 EKX45078.1 - 3.7e-30 105.1 20.5 4.8e-30 104.7 20.5 1.1 1 0 0 1 1 1 1 Sodium:solute symporter family Synaptobrevin PF00957.21 EKX45079.1 - 3.2e-32 110.2 5.3 4.8e-32 109.6 5.3 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EKX45079.1 - 2.2e-25 88.5 0.1 3.5e-25 87.8 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain SpoIIAA-like PF11964.8 EKX45079.1 - 0.075 14.1 0.7 0.22 12.6 0.4 1.8 1 1 1 2 2 2 0 SpoIIAA-like MCU PF04678.13 EKX45079.1 - 0.098 12.7 1.4 0.14 12.2 1.3 1.3 1 1 0 1 1 1 0 Mitochondrial calcium uniporter Mitofilin PF09731.9 EKX45080.1 - 3.5e-26 92.2 39.5 1.9e-25 89.8 39.6 2.0 1 1 0 1 1 1 1 Mitochondrial inner membrane protein Apolipoprotein PF01442.18 EKX45080.1 - 6.2 6.6 45.5 0.076 12.9 26.9 3.0 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain MAP70 PF07058.11 EKX45081.1 - 6.7e-07 28.4 16.9 6.7e-06 25.1 9.2 2.5 2 1 0 2 2 2 2 Microtubule-associated protein 70 Lebercilin PF15619.6 EKX45081.1 - 0.0012 18.6 8.7 0.0012 18.6 8.7 4.0 2 1 0 3 3 3 2 Ciliary protein causing Leber congenital amaurosis disease DUF724 PF05266.14 EKX45081.1 - 0.0023 17.8 4.9 0.0023 17.8 4.9 4.1 4 0 0 4 4 4 1 Protein of unknown function (DUF724) ATG16 PF08614.11 EKX45081.1 - 0.0025 18.1 8.4 0.0025 18.1 8.4 3.7 3 1 0 4 4 3 1 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 EKX45081.1 - 0.005 16.8 1.2 0.005 16.8 1.2 6.0 5 2 1 6 6 6 2 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 EKX45081.1 - 0.015 15.4 9.8 0.015 15.4 9.8 4.4 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BRE1 PF08647.11 EKX45081.1 - 0.028 14.5 1.7 0.028 14.5 1.7 4.4 4 1 0 4 4 4 0 BRE1 E3 ubiquitin ligase CASP_C PF08172.12 EKX45081.1 - 0.03 13.6 14.1 0.33 10.2 1.8 3.4 3 0 0 3 3 3 0 CASP C terminal DUF4795 PF16043.5 EKX45081.1 - 0.052 13.2 16.4 0.33 10.5 9.4 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF4407 PF14362.6 EKX45081.1 - 0.071 12.4 12.3 0.57 9.5 1.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) TSC22 PF01166.18 EKX45081.1 - 0.078 13.3 0.4 0.078 13.3 0.4 4.3 4 0 0 4 4 4 0 TSC-22/dip/bun family Spc7 PF08317.11 EKX45081.1 - 0.08 11.8 26.9 0.029 13.3 8.2 3.4 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF4988 PF16378.5 EKX45081.1 - 0.099 12.3 0.1 0.099 12.3 0.1 2.3 3 1 0 3 3 2 0 Domain of unknown function GAS PF13851.6 EKX45081.1 - 0.11 11.9 26.9 0.45 9.8 4.1 4.6 3 2 2 5 5 5 0 Growth-arrest specific micro-tubule binding NPV_P10 PF05531.12 EKX45081.1 - 0.14 12.7 8.1 15 6.1 0.0 4.6 5 0 0 5 5 4 0 Nucleopolyhedrovirus P10 protein DUF3972 PF13118.6 EKX45081.1 - 0.19 12.2 12.7 2.5 8.6 0.3 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3972) Ntox28 PF15605.6 EKX45081.1 - 0.36 11.1 8.1 1.1 9.5 0.3 3.3 2 1 0 2 2 2 0 Bacterial toxin 28 Fib_alpha PF08702.10 EKX45081.1 - 1.7 8.8 17.6 7.1 6.8 4.0 4.0 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 EKX45081.1 - 3.9 7.3 29.6 0.98 9.2 1.3 5.5 5 0 0 5 5 5 0 Septum formation initiator TMF_TATA_bd PF12325.8 EKX45081.1 - 5.1 7.4 32.7 0.064 13.5 7.1 4.9 3 1 2 5 5 5 0 TATA element modulatory factor 1 TATA binding TBCA PF02970.16 EKX45081.1 - 5.2 7.5 15.3 0.45 10.9 1.1 4.1 3 1 1 4 4 4 0 Tubulin binding cofactor A bZIP_1 PF00170.21 EKX45081.1 - 6.6 6.9 28.8 0.24 11.5 0.4 6.2 4 3 1 6 6 6 0 bZIP transcription factor Tropomyosin_1 PF12718.7 EKX45081.1 - 9.7 6.3 32.8 1.4 9.1 5.8 4.1 4 1 0 4 4 3 0 Tropomyosin like ADIP PF11559.8 EKX45081.1 - 9.9 6.2 32.3 0.69 10.0 7.5 4.3 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding MIP PF00230.20 EKX45083.1 - 4.8e-20 72.3 4.8 5.5e-20 72.1 4.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF3645 PF12359.8 EKX45085.1 - 0.039 13.3 0.1 0.078 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3645) DUF1776 PF08643.10 EKX45085.1 - 0.073 12.4 0.2 0.5 9.7 0.1 2.2 2 1 0 2 2 2 0 Fungal family of unknown function (DUF1776) RWP-RK PF02042.15 EKX45086.1 - 7.8e-13 48.2 0.0 1.1e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 RWP-RK domain HTH_24 PF13412.6 EKX45086.1 - 2.7e-06 26.8 1.9 4.3e-06 26.2 0.2 2.1 2 1 1 3 3 3 1 Winged helix-turn-helix DNA-binding HTH_31 PF13560.6 EKX45086.1 - 0.00011 22.5 0.6 0.0037 17.6 0.3 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_AsnC-type PF13404.6 EKX45086.1 - 0.0019 18.0 1.7 0.0098 15.7 0.2 2.2 2 0 0 2 2 2 1 AsnC-type helix-turn-helix domain HTH_23 PF13384.6 EKX45086.1 - 0.0038 17.0 0.2 0.018 14.9 0.0 2.1 2 1 1 3 3 3 1 Homeodomain-like domain HTH_3 PF01381.22 EKX45086.1 - 0.05 13.7 0.1 0.082 13.0 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix HTH_8 PF02954.19 EKX45086.1 - 0.062 13.1 0.2 0.9 9.4 0.1 2.2 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family HTH_28 PF13518.6 EKX45086.1 - 0.11 12.6 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 EKX45086.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 RWP-RK PF02042.15 EKX45087.1 - 4.7e-09 36.1 0.0 7.4e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_24 PF13412.6 EKX45087.1 - 0.014 14.9 0.4 0.09 12.3 0.2 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding AHD PF17793.1 EKX45088.1 - 0.029 14.1 0.2 0.052 13.4 0.2 1.5 1 1 0 1 1 1 0 ANC1 homology domain (AHD) TMEM208_SND2 PF05620.11 EKX45088.1 - 0.22 11.3 2.3 0.25 11.1 2.3 1.1 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 PPL5 PF18168.1 EKX45088.1 - 0.28 10.4 4.5 0.31 10.3 4.5 1.0 1 0 0 1 1 1 0 Prim-pol family 5 Med19 PF10278.9 EKX45088.1 - 0.32 10.9 12.1 0.43 10.5 12.1 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Hid1 PF12722.7 EKX45088.1 - 0.56 8.3 3.7 0.62 8.1 3.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein eIF-3c_N PF05470.12 EKX45088.1 - 0.62 8.3 9.8 0.68 8.2 9.6 1.2 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF3464 PF11947.8 EKX45088.1 - 1.3 8.8 5.0 1.6 8.5 5.0 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 TMP_2 PF06791.13 EKX45089.1 - 0.013 15.2 3.2 0.062 13.0 0.2 2.2 2 0 0 2 2 2 0 Prophage tail length tape measure protein Syntaxin-6_N PF09177.11 EKX45089.1 - 0.016 15.7 1.4 0.44 11.1 0.1 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal HBM PF16591.5 EKX45089.1 - 0.032 13.6 5.1 0.25 10.8 0.2 2.3 2 0 0 2 2 2 0 Helical bimodular sensor domain T3SSipB PF16535.5 EKX45089.1 - 0.097 13.1 11.0 0.6 10.6 10.2 2.4 1 1 0 1 1 1 0 Type III cell invasion protein SipB Occludin_ELL PF07303.13 EKX45089.1 - 0.11 13.3 3.2 0.69 10.7 0.1 3.0 1 1 2 4 4 4 0 Occludin homology domain Rh5 PF18515.1 EKX45089.1 - 0.16 11.2 0.1 0.16 11.2 0.1 2.6 2 1 0 2 2 2 0 Rh5 coiled-coil domain DUF948 PF06103.11 EKX45089.1 - 0.48 10.7 7.0 0.94 9.8 0.6 3.3 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TBCC_N PF16752.5 EKX45089.1 - 4.4 7.8 7.2 0.46 11.0 0.8 2.4 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain SurA_N_2 PF13623.6 EKX45090.1 - 0.019 14.8 0.5 0.035 14.0 0.5 1.4 1 0 0 1 1 1 0 SurA N-terminal domain SurA_N_3 PF13624.6 EKX45090.1 - 0.047 13.5 0.1 0.07 12.9 0.1 1.3 1 0 0 1 1 1 0 SurA N-terminal domain ENTH PF01417.20 EKX45091.1 - 9.1e-11 41.9 0.0 1.1e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 ENTH domain PCO_ADO PF07847.12 EKX45093.1 - 0.14 11.6 0.2 0.23 10.9 0.2 1.3 1 0 0 1 1 1 0 PCO_ADO Trp_repressor PF01371.19 EKX45093.1 - 0.56 10.4 2.2 4 7.6 0.9 2.6 3 0 0 3 3 3 0 Trp repressor protein Sde2_N_Ubi PF13019.6 EKX45094.1 - 3.2e-22 79.1 0.4 3.2e-22 79.1 0.4 2.5 2 1 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain Telomere_Sde2_2 PF13297.6 EKX45094.1 - 5.3e-20 70.8 0.0 1.3e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 Telomere stability C-terminal Pneumo_att_G PF05539.11 EKX45094.1 - 0.05 13.2 5.6 0.075 12.6 5.6 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G TRAUB PF08164.12 EKX45094.1 - 0.066 13.7 0.7 0.066 13.7 0.7 2.7 2 1 0 2 2 2 0 Apoptosis-antagonizing transcription factor, C-terminal Myco_haema PF05692.12 EKX45094.1 - 2.8 6.8 6.6 0.89 8.5 3.3 1.9 1 1 0 1 1 1 0 Mycoplasma haemagglutinin DUF572 PF04502.13 EKX45094.1 - 8.6 5.9 30.6 17 4.9 30.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ank_5 PF13857.6 EKX45095.1 - 3.3e-11 43.2 0.1 0.0003 21.0 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX45095.1 - 2.1e-10 41.1 0.0 4.6e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX45095.1 - 3.4e-10 39.2 0.1 0.0004 20.6 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EKX45095.1 - 2.3e-08 34.4 0.1 0.0021 18.6 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX45095.1 - 3.7e-08 33.4 0.7 0.00011 22.5 0.3 2.7 2 0 0 2 2 2 2 Ankyrin repeat Acetyltransf_1 PF00583.25 EKX45095.1 - 3.7e-06 27.1 0.2 8.1e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EKX45095.1 - 4.3e-06 26.7 0.3 2.9e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EKX45095.1 - 4.2e-05 23.9 0.0 9e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EKX45095.1 - 0.005 16.8 0.0 0.0095 15.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EKX45095.1 - 0.025 14.7 0.3 0.066 13.4 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EKX45095.1 - 0.098 13.3 0.1 0.42 11.3 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Ku PF02735.16 EKX45096.1 - 3.3e-31 108.6 0.0 6.5e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 EKX45096.1 - 2.2e-22 79.9 1.1 3.6e-22 79.2 1.1 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain SAP PF02037.27 EKX45096.1 - 1.1e-08 34.7 0.3 1.1e-08 34.7 0.3 2.3 2 0 0 2 2 2 1 SAP domain Rho_N PF07498.12 EKX45096.1 - 0.00018 21.4 0.1 0.00042 20.2 0.1 1.7 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain Ku_C PF03730.14 EKX45096.1 - 0.00074 20.2 2.0 0.0047 17.6 0.0 2.7 3 0 0 3 3 3 1 Ku70/Ku80 C-terminal arm VWA PF00092.28 EKX45096.1 - 0.02 15.1 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain LETM1 PF07766.13 EKX45096.1 - 0.078 12.3 0.2 0.22 10.8 0.0 1.8 2 0 0 2 2 2 0 LETM1-like protein WCCH PF03716.14 EKX45097.1 - 2.6 7.8 15.7 4 7.2 4.4 3.9 3 0 0 3 3 3 0 WCCH motif WD40 PF00400.32 EKX45098.1 - 1.2e-57 190.6 14.9 7.3e-11 42.4 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX45098.1 - 1.5e-14 54.0 0.1 0.00044 20.5 0.0 5.3 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX45098.1 - 4.6e-07 29.1 0.5 0.73 8.7 0.1 4.6 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EKX45098.1 - 1.8e-06 28.0 0.1 0.00024 21.0 0.0 2.9 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EKX45098.1 - 5.2e-06 26.0 0.0 0.034 13.5 0.0 3.1 3 1 0 3 3 3 2 WD40-like domain DUF2415 PF10313.9 EKX45098.1 - 0.00021 21.2 0.0 2.9 7.9 0.0 3.7 3 0 0 3 3 3 2 Uncharacterised protein domain (DUF2415) Frtz PF11768.8 EKX45098.1 - 0.00039 18.9 0.0 0.12 10.6 0.0 2.9 2 1 2 4 4 4 2 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 EKX45098.1 - 0.015 14.0 3.2 3.7 6.1 0.0 3.1 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Sushi PF00084.20 EKX45099.1 - 0.012 16.2 0.5 0.015 15.8 0.5 1.3 1 0 0 1 1 1 0 Sushi repeat (SCR repeat) Methyltransf_21 PF05050.12 EKX45100.1 - 2.2e-19 70.1 0.0 3.3e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain V_cholerae_RfbT PF05575.11 EKX45100.1 - 0.04 13.2 0.3 0.42 9.8 0.3 2.1 1 1 0 1 1 1 0 Vibrio cholerae RfbT protein Met_10 PF02475.16 EKX45100.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_16 PF10294.9 EKX45101.1 - 2.7e-16 59.8 0.0 5.7e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase PDZ_6 PF17820.1 EKX45101.1 - 3.9e-11 42.6 0.1 3.5e-10 39.6 0.0 2.5 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX45101.1 - 1.8e-10 41.0 0.0 2.5e-09 37.4 0.0 2.6 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX45101.1 - 2e-08 34.4 0.3 1.6e-07 31.5 0.1 2.4 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 EKX45101.1 - 0.00018 21.4 0.2 0.0034 17.3 0.1 2.5 2 0 0 2 2 2 1 Tricorn protease PDZ domain Methyltransf_23 PF13489.6 EKX45101.1 - 0.0032 17.3 0.0 0.0072 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX45101.1 - 0.0048 17.6 0.0 0.014 16.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EKX45101.1 - 0.02 14.7 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 EKX45101.1 - 0.073 13.7 0.0 0.32 11.7 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Penaeidin PF05927.11 EKX45102.1 - 0.0006 20.5 0.5 0.71 10.7 0.0 2.3 2 0 0 2 2 2 2 Penaeidin DUF1823 PF08853.11 EKX45102.1 - 0.093 12.9 0.1 0.47 10.7 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1823) CENP-X PF09415.10 EKX45102.1 - 0.11 12.9 1.0 0.21 11.9 1.0 1.6 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Keratin_matx PF04579.12 EKX45102.1 - 0.14 12.5 2.2 11 6.4 0.1 2.3 2 0 0 2 2 2 0 Keratin, high-sulphur matrix protein RNA_pol_Rpb6 PF01192.22 EKX45103.1 - 5.6e-18 64.6 0.0 7.6e-18 64.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 DUF4201 PF13870.6 EKX45104.1 - 2e-08 34.2 41.0 0.00024 20.9 5.4 3.1 1 1 2 3 3 3 2 Domain of unknown function (DUF4201) Cep57_CLD PF14073.6 EKX45104.1 - 9.7e-06 25.7 38.9 0.0035 17.4 27.9 2.3 1 1 1 2 2 2 2 Centrosome localisation domain of Cep57 HALZ PF02183.18 EKX45104.1 - 0.0083 16.3 0.9 0.0083 16.3 0.9 6.7 6 1 1 7 7 6 1 Homeobox associated leucine zipper Cluap1 PF10234.9 EKX45104.1 - 0.0086 15.5 12.6 0.0086 15.5 12.6 3.0 1 1 2 3 3 3 1 Clusterin-associated protein-1 DUF2046 PF09755.9 EKX45104.1 - 0.013 14.8 38.1 0.058 12.6 10.5 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) CLZ PF16526.5 EKX45104.1 - 0.035 14.5 1.8 0.035 14.5 1.8 5.2 1 1 4 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc7 PF08317.11 EKX45104.1 - 0.037 12.9 39.2 0.015 14.2 24.2 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein KASH_CCD PF14662.6 EKX45104.1 - 0.042 13.7 42.9 0.39 10.5 12.6 3.0 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH FlaC_arch PF05377.11 EKX45104.1 - 0.058 13.8 21.5 0.086 13.3 0.6 5.7 3 2 3 6 6 6 0 Flagella accessory protein C (FlaC) Lebercilin PF15619.6 EKX45104.1 - 0.14 11.8 48.1 0.19 11.4 26.1 3.2 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Prefoldin_2 PF01920.20 EKX45104.1 - 0.15 12.0 36.4 0.4 10.6 2.8 4.8 1 1 1 3 3 3 0 Prefoldin subunit Baculo_PEP_C PF04513.12 EKX45104.1 - 0.16 12.0 20.8 0.3 11.1 9.6 2.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 EKX45104.1 - 0.18 11.8 23.3 0.23 11.5 6.7 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 EKX45104.1 - 0.19 11.6 32.8 0.98 9.2 14.6 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Leu_zip PF15294.6 EKX45104.1 - 0.22 11.0 33.6 0.12 11.9 18.4 2.2 1 1 1 2 2 2 0 Leucine zipper CENP-F_leu_zip PF10473.9 EKX45104.1 - 0.24 11.4 42.1 3.3 7.7 8.9 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prominin PF05478.11 EKX45104.1 - 0.25 9.3 23.7 0.22 9.4 11.7 2.3 1 1 1 2 2 2 0 Prominin Tropomyosin_1 PF12718.7 EKX45104.1 - 0.43 10.7 39.9 1.6 8.8 8.0 3.6 1 1 2 3 3 3 0 Tropomyosin like NPV_P10 PF05531.12 EKX45104.1 - 0.57 10.7 24.9 6.1 7.4 4.2 4.2 1 1 3 4 4 4 0 Nucleopolyhedrovirus P10 protein ATG16 PF08614.11 EKX45104.1 - 0.67 10.1 43.6 1.3 9.3 4.5 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HAP1_N PF04849.13 EKX45104.1 - 0.68 9.1 42.5 0.021 14.0 25.9 2.7 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Taxilin PF09728.9 EKX45104.1 - 0.83 8.8 39.1 1.1 8.4 39.1 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein ZapB PF06005.12 EKX45104.1 - 0.91 10.0 45.1 0.79 10.2 7.5 4.0 1 1 2 4 4 4 0 Cell division protein ZapB TMF_TATA_bd PF12325.8 EKX45104.1 - 1.3 9.3 37.4 0.91 9.8 9.9 3.6 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 EKX45104.1 - 1.4 9.5 44.1 2.6 8.6 21.2 2.8 1 1 2 3 3 3 0 Apg6 coiled-coil region DUF745 PF05335.13 EKX45104.1 - 1.4 8.6 23.1 0.21 11.3 9.7 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF745) FAM76 PF16046.5 EKX45104.1 - 1.8 7.9 25.5 2.5 7.4 25.5 1.1 1 0 0 1 1 1 0 FAM76 protein DUF812 PF05667.11 EKX45104.1 - 1.9 7.3 32.9 1.9 7.2 20.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF812) FPP PF05911.11 EKX45104.1 - 2.1 6.4 36.2 5.9 5.0 36.2 1.6 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil YabA PF06156.13 EKX45104.1 - 2.1 9.0 31.0 0.37 11.4 3.5 4.2 1 1 3 4 4 4 0 Initiation control protein YabA DUF4472 PF14739.6 EKX45104.1 - 2.2 9.1 31.5 1.4 9.6 4.5 3.3 1 1 1 3 3 3 0 Domain of unknown function (DUF4472) PI3K_P85_iSH2 PF16454.5 EKX45104.1 - 2.2 7.8 38.4 1.6 8.3 11.9 3.3 1 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain GAS PF13851.6 EKX45104.1 - 2.4 7.5 40.8 0.26 10.6 23.1 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding SHE3 PF17078.5 EKX45104.1 - 2.7 7.6 34.7 0.069 12.9 6.2 2.4 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 PI_PP_I PF18363.1 EKX45104.1 - 3 8.1 6.6 15 5.8 2.1 3.1 1 1 2 3 3 3 0 Phosphoinositide phosphatase insertion domain DUF1054 PF06335.12 EKX45104.1 - 3.5 7.5 9.4 1.1 9.1 6.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1054) DUF948 PF06103.11 EKX45104.1 - 3.7 7.9 13.8 0.092 13.0 2.8 3.0 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) LPP PF04728.13 EKX45104.1 - 4.5 7.7 14.7 9.9 6.6 0.6 4.4 3 2 1 4 4 4 0 Lipoprotein leucine-zipper Csm1_N PF18504.1 EKX45104.1 - 5.7 7.4 35.6 0.34 11.3 9.8 5.1 1 1 5 6 6 6 0 Csm1 N-terminal domain ADIP PF11559.8 EKX45104.1 - 8.1 6.5 42.8 1.7 8.7 12.7 3.4 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding DUF4962 PF16332.5 EKX45104.1 - 8.3 4.8 14.8 0.37 9.2 7.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4962) DASH_Dam1 PF08653.10 EKX45104.1 - 8.5 6.3 13.0 15 5.5 0.1 4.3 5 1 1 6 6 3 0 DASH complex subunit Dam1 DASH_Dad4 PF08650.10 EKX45104.1 - 8.6 6.4 15.6 0.59 10.2 0.7 3.8 2 2 3 5 5 5 0 DASH complex subunit Dad4 HD_3 PF13023.6 EKX45106.1 - 2.4e-47 160.9 0.0 2.9e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 EKX45106.1 - 1.3e-12 47.8 0.0 1.7e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 EKX45106.1 - 0.00024 21.3 0.0 0.00048 20.3 0.0 1.5 1 0 0 1 1 1 1 HD domain LMWPc PF01451.21 EKX45107.1 - 1.9e-15 57.5 0.4 6.8e-14 52.5 0.4 2.1 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase RunxI PF08504.11 EKX45107.1 - 0.14 12.9 0.0 0.26 12.0 0.0 1.4 1 0 0 1 1 1 0 Runx inhibition domain PROCN PF08083.11 EKX45108.1 - 2.9e-235 780.5 8.4 4.9e-235 779.7 8.4 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 EKX45108.1 - 1.1e-127 424.3 0.3 1.9e-127 423.6 0.3 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 EKX45108.1 - 2e-89 297.6 2.5 4.9e-89 296.3 2.5 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 EKX45108.1 - 1.1e-86 288.4 2.3 1.1e-86 288.4 2.3 2.2 3 0 0 3 3 3 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 EKX45108.1 - 4.7e-74 246.8 0.0 1.1e-73 245.7 0.0 1.7 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 EKX45108.1 - 4.7e-54 181.6 0.2 1.2e-53 180.2 0.2 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 EKX45108.1 - 1e-45 154.0 0.9 2.8e-45 152.6 0.9 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 EKX45108.1 - 1.1e-06 28.6 0.0 9.8e-06 25.5 0.0 2.3 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Ephrin_rec_like PF07699.13 EKX45109.1 - 1.1e-33 114.8 215.2 9.1e-07 28.5 4.0 18.7 7 4 13 20 20 20 15 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX45109.1 - 2.7e-17 62.9 180.0 1.9e-06 28.2 11.9 20.7 9 6 12 22 22 22 12 TNFR/NGFR cysteine-rich region NCD3G PF07562.14 EKX45109.1 - 4.4e-05 23.3 194.8 0.026 14.5 5.3 18.7 8 5 7 19 19 19 14 Nine Cysteines Domain of family 3 GPCR Ephrin_rec_like PF07699.13 EKX45110.1 - 4.5e-44 148.0 158.5 1.7e-08 34.1 7.8 16.0 10 6 6 16 16 16 13 Putative ephrin-receptor like NCD3G PF07562.14 EKX45110.1 - 6.1e-22 77.3 127.6 0.00055 19.9 6.2 12.6 10 2 2 13 13 13 11 Nine Cysteines Domain of family 3 GPCR Kelch_4 PF13418.6 EKX45110.1 - 2.2e-15 56.4 9.2 0.00014 21.8 2.5 4.7 3 1 1 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.6 EKX45110.1 - 7.2e-15 54.9 7.5 1.2e-09 38.2 0.2 4.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 EKX45110.1 - 2e-12 46.8 4.6 0.00014 21.8 0.1 3.9 3 1 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 EKX45110.1 - 2.8e-08 33.8 6.7 0.0067 16.7 0.1 5.0 4 1 1 5 5 5 2 Kelch motif Kelch_2 PF07646.15 EKX45110.1 - 8.6e-05 22.4 7.9 0.23 11.5 0.1 5.0 3 1 1 4 4 4 2 Kelch motif zf_CCCH_4 PF18345.1 EKX45112.1 - 3.3e-07 30.1 2.2 8.5e-07 28.8 2.2 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 EKX45112.1 - 8.3e-07 28.8 0.7 8.3e-07 28.8 0.7 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EKX45112.1 - 0.0028 18.3 0.3 0.006 17.3 0.3 1.5 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 EKX45112.1 - 0.015 15.8 1.7 0.015 15.8 1.7 2.3 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 EKX45112.1 - 0.018 14.8 1.6 0.018 14.8 1.6 2.2 2 0 0 2 2 2 0 CCCH-type zinc finger AvrRpt-cleavage PF05627.11 EKX45114.1 - 0.086 12.2 0.1 0.19 11.1 0.1 1.6 1 0 0 1 1 1 0 Cleavage site for pathogenic type III effector avirulence factor Avr PspA_IM30 PF04012.12 EKX45115.1 - 0.00063 19.4 3.7 0.0018 17.9 3.5 1.6 1 1 1 2 2 2 1 PspA/IM30 family MAD PF05557.13 EKX45115.1 - 0.0021 16.6 1.1 0.0022 16.4 1.1 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein DASH_Duo1 PF08651.10 EKX45115.1 - 0.0042 16.8 1.1 0.0042 16.8 1.1 1.6 2 0 0 2 2 2 1 DASH complex subunit Duo1 DUF848 PF05852.11 EKX45115.1 - 0.007 16.5 1.4 0.0088 16.2 1.4 1.1 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) Baculo_PEP_C PF04513.12 EKX45115.1 - 0.015 15.4 1.8 0.019 15.0 1.8 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF16 PF01519.16 EKX45115.1 - 0.033 14.7 1.8 0.066 13.7 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 Prominin PF05478.11 EKX45115.1 - 0.038 12.0 0.9 0.041 11.9 0.9 1.0 1 0 0 1 1 1 0 Prominin COG5 PF10392.9 EKX45115.1 - 0.051 13.8 0.7 0.059 13.5 0.7 1.1 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Rogdi_lz PF10259.9 EKX45115.1 - 0.051 13.0 0.6 0.065 12.7 0.6 1.2 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein DUF4200 PF13863.6 EKX45115.1 - 0.065 13.6 1.7 0.074 13.4 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) RPW8 PF05659.11 EKX45115.1 - 0.095 12.4 2.3 1.1 9.0 0.5 2.0 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF2203 PF09969.9 EKX45115.1 - 0.11 13.2 2.4 0.14 12.9 1.0 1.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Fmp27_WPPW PF10359.9 EKX45115.1 - 0.12 11.2 1.1 0.14 11.0 1.1 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF1664 PF07889.12 EKX45115.1 - 0.13 12.3 2.1 0.23 11.5 1.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) THOC7 PF05615.13 EKX45115.1 - 0.18 12.1 3.8 0.93 9.8 3.8 1.8 1 1 0 1 1 1 0 Tho complex subunit 7 Tweety PF04906.13 EKX45115.1 - 0.19 10.4 1.1 0.22 10.1 1.1 1.1 1 0 0 1 1 1 0 Tweety XhlA PF10779.9 EKX45115.1 - 0.34 11.2 2.2 5.7 7.2 0.2 2.5 1 1 0 2 2 2 0 Haemolysin XhlA EF-hand_5 PF13202.6 EKX45116.1 - 4.1e-18 64.0 11.0 1.4e-05 24.3 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_1 PF00036.32 EKX45116.1 - 1.2e-17 62.1 7.3 9.1e-05 21.7 0.3 4.8 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EKX45116.1 - 2.2e-15 55.2 7.0 0.0011 18.8 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 EKX45116.1 - 2.3e-15 56.8 22.3 1.9e-06 28.2 0.3 3.9 2 1 3 5 5 5 5 EF-hand domain pair EF-hand_10 PF14788.6 EKX45116.1 - 5.6e-07 29.3 4.6 0.19 11.6 0.2 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EKX45116.1 - 1.2e-06 28.2 7.9 0.064 13.1 0.0 4.1 4 1 0 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX45116.1 - 1.7e-06 28.3 12.9 0.045 14.1 3.1 4.1 3 1 1 4 4 4 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EKX45116.1 - 0.099 12.6 6.8 4.4 7.3 0.4 3.7 2 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand XRCC4 PF06632.12 EKX45117.1 - 0.17 10.7 8.0 0.27 10.1 8.0 1.3 1 1 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 EnY2 PF10163.9 EKX45118.1 - 0.034 14.5 0.1 0.13 12.7 0.0 1.9 2 0 0 2 2 2 0 Transcription factor e(y)2 DNA_pol_B PF00136.21 EKX45120.1 - 1.3e-119 400.0 0.0 1.5e-119 399.7 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.6 EKX45120.1 - 3e-05 24.4 10.3 0.00049 20.5 5.7 2.8 3 0 0 3 3 3 2 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 EKX45120.1 - 0.038 12.8 0.0 0.073 11.9 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral TPR_8 PF13181.6 EKX45122.1 - 0.0003 20.7 0.5 1.3 9.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX45122.1 - 0.0039 17.7 0.1 5.8 7.5 0.1 4.4 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX45122.1 - 0.007 17.1 0.0 43 5.3 0.0 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 EKX45122.1 - 0.04 13.6 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 TPR repeat TPR_2 PF07719.17 EKX45122.1 - 0.06 13.5 0.0 7.4 7.0 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat NinB PF05772.12 EKX45122.1 - 0.12 12.2 0.0 17 5.3 0.0 2.4 2 0 0 2 2 2 0 NinB protein TPR_12 PF13424.6 EKX45122.1 - 0.63 10.4 3.4 26 5.2 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Enkurin PF13864.6 EKX45123.1 - 0.016 15.6 1.1 0.041 14.3 0.7 1.8 2 0 0 2 2 2 0 Calmodulin-binding TPR_17 PF13431.6 EKX45124.1 - 4.7e-10 39.1 0.0 0.036 14.4 0.0 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX45124.1 - 1.3e-09 37.5 0.0 1.1e-05 25.1 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX45124.1 - 2.2e-09 36.7 0.0 2.2e-05 24.2 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX45124.1 - 3.2e-09 36.3 0.0 9.8e-05 22.3 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX45124.1 - 3.9e-06 26.5 0.0 0.00056 19.5 0.0 2.9 2 1 1 3 3 3 1 TPR repeat TPR_12 PF13424.6 EKX45124.1 - 3.3e-05 24.1 0.0 0.00018 21.7 0.0 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX45124.1 - 8e-05 22.4 0.0 0.014 15.3 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX45124.1 - 0.00024 21.6 0.0 0.056 14.3 0.0 2.9 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX45124.1 - 0.0017 19.0 0.0 0.45 11.2 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX45124.1 - 0.0021 18.0 0.0 0.32 11.1 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 EKX45124.1 - 0.027 15.1 0.1 1.2 10.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.17 EKX45124.1 - 0.15 12.5 0.0 0.38 11.2 0.0 1.8 2 1 0 2 2 2 0 Bacterial transcriptional activator domain TPR_9 PF13371.6 EKX45124.1 - 0.15 12.2 0.0 1.9 8.7 0.0 2.1 1 1 2 3 3 3 0 Tetratricopeptide repeat TIG PF01833.24 EKX45125.1 - 5e-07 29.7 0.2 0.00086 19.3 0.2 3.3 2 1 0 2 2 2 2 IPT/TIG domain SRF-TF PF00319.18 EKX45125.1 - 0.00011 21.6 0.0 0.0003 20.2 0.0 1.7 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Pribosyltran PF00156.27 EKX45126.1 - 1.2e-13 50.9 0.0 1.5e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain THF_DHG_CYH_C PF02882.19 EKX45126.1 - 0.021 14.1 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F5_F8_type_C PF00754.25 EKX45127.1 - 2e-06 27.9 0.0 2.9e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain Filamin PF00630.19 EKX45128.1 - 6.3e-15 55.9 0.2 5.8e-05 23.9 0.0 3.8 3 1 1 4 4 4 3 Filamin/ABP280 repeat YtkA PF13115.6 EKX45128.1 - 0.0083 16.7 0.0 3.5 8.3 0.0 3.4 4 0 0 4 4 4 1 YtkA-like TIG PF01833.24 EKX45129.1 - 4.4e-27 94.0 19.1 0.0025 17.8 1.4 8.4 8 0 0 8 8 8 7 IPT/TIG domain DUF5620 PF18522.1 EKX45129.1 - 0.022 15.1 0.4 17 5.9 0.1 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5620) AAA_29 PF13555.6 EKX45129.1 - 0.025 14.3 0.0 15 5.4 0.0 3.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain TctC PF03401.14 EKX45129.1 - 0.037 13.1 0.8 8.8 5.3 0.1 2.8 2 2 2 4 4 4 0 Tripartite tricarboxylate transporter family receptor CX9C PF16860.5 EKX45129.1 - 1.9 8.6 8.5 12 6.0 1.1 2.6 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DSL PF01414.19 EKX45130.1 - 2.4e-12 46.9 80.0 0.00011 22.4 11.3 4.0 4 0 0 4 4 4 3 Delta serrate ligand EGF_2 PF07974.13 EKX45130.1 - 8.7e-12 45.2 96.3 0.0002 21.6 15.7 6.3 6 1 1 7 7 7 4 EGF-like domain Laminin_EGF PF00053.24 EKX45130.1 - 1.5e-10 41.0 73.3 0.003 17.7 17.9 4.5 1 1 3 4 4 4 4 Laminin EGF domain EGF PF00008.27 EKX45130.1 - 1.1e-08 35.2 63.9 0.00014 22.1 8.6 5.3 5 0 0 5 5 5 4 EGF-like domain hEGF PF12661.7 EKX45130.1 - 0.011 16.3 6.4 0.011 16.3 6.4 7.3 7 2 0 7 7 7 0 Human growth factor-like EGF Coprogen_oxidas PF01218.18 EKX45131.1 - 2.9e-134 446.4 0.1 3.4e-134 446.2 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase WASH-7_N PF14745.6 EKX45132.1 - 1.2e-106 357.6 0.0 1.6e-106 357.1 0.0 1.2 1 0 0 1 1 1 1 WASH complex subunit 7, N-terminal WASH-7_mid PF14744.6 EKX45132.1 - 4.3e-101 338.5 3.0 1.1e-100 337.1 1.2 2.3 2 0 0 2 2 2 1 WASH complex subunit 7 DKCLD PF08068.12 EKX45133.1 - 2.7e-34 117.0 0.3 4.6e-33 113.1 0.3 2.5 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 EKX45133.1 - 5.1e-22 77.8 1.2 5.1e-22 77.8 1.2 1.8 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 EKX45133.1 - 2.8e-20 73.2 9.6 3.8e-20 72.8 0.5 3.5 2 1 0 2 2 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 EKX45133.1 - 9.3e-20 70.4 1.8 1.8e-19 69.4 1.8 1.5 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 EKX45133.1 - 0.067 13.5 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 UPF0113 PUA domain DUF913 PF06025.12 EKX45133.1 - 0.27 10.2 5.7 0.48 9.4 5.7 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 EKX45133.1 - 1.1 9.0 18.1 1.9 8.2 18.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC27 PF09507.10 EKX45133.1 - 2.4 7.4 28.5 4.1 6.7 28.5 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Coilin_N PF15862.5 EKX45133.1 - 3.4 7.5 21.2 0.048 13.5 13.4 1.9 2 0 0 2 2 2 0 Coilin N-terminus CPSF100_C PF13299.6 EKX45133.1 - 3.9 7.6 12.2 9 6.4 12.2 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Nucleo_P87 PF07267.11 EKX45133.1 - 6 5.6 14.3 8.5 5.1 14.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TFIIF_alpha PF05793.12 EKX45133.1 - 8.4 4.9 33.7 14 4.1 33.7 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TPR_2 PF07719.17 EKX45135.1 - 5.2e-31 104.3 0.2 5.8e-07 29.1 0.0 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 EKX45135.1 - 1.3e-24 84.9 0.2 4.3e-07 29.5 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 EKX45135.1 - 2e-23 82.4 10.2 1.1e-07 32.0 0.0 5.3 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 EKX45135.1 - 2.3e-21 74.6 0.6 1.7e-07 31.2 0.0 6.5 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 EKX45135.1 - 2.6e-19 67.8 0.0 0.00066 19.7 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX45135.1 - 7.1e-19 66.9 3.7 0.0073 17.0 0.1 5.8 3 1 3 6 6 5 5 Tetratricopeptide repeat TPR_11 PF13414.6 EKX45135.1 - 5e-15 54.9 3.0 0.0004 20.0 0.0 6.7 3 2 5 8 8 7 3 TPR repeat TPR_16 PF13432.6 EKX45135.1 - 9.7e-15 54.9 7.9 8.4e-06 26.3 0.0 4.5 4 1 0 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX45135.1 - 6.6e-13 47.7 0.1 0.022 14.8 0.0 6.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX45135.1 - 3.1e-12 46.8 5.9 0.0015 19.0 0.0 4.3 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX45135.1 - 8.8e-12 44.5 12.5 0.00024 20.8 0.1 5.8 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 EKX45135.1 - 1.3e-11 44.3 4.2 0.31 11.8 0.1 6.1 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 EKX45135.1 - 1.1e-07 31.9 1.8 0.4 10.9 0.2 4.8 3 1 2 5 5 5 2 Tetratricopeptide repeat NARP1 PF12569.8 EKX45135.1 - 1.2e-07 31.1 0.0 0.36 9.7 0.0 3.9 2 1 2 4 4 4 3 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 EKX45135.1 - 2.2e-07 30.4 1.8 0.11 11.6 0.0 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX45135.1 - 1.1e-06 28.7 1.1 0.043 14.0 0.0 3.5 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 EKX45135.1 - 1.8e-06 28.0 14.2 0.0064 17.0 0.2 5.9 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX45135.1 - 4.9e-05 22.9 0.3 0.01 15.2 0.2 2.4 1 1 1 2 2 2 2 MalT-like TPR region Coatomer_E PF04733.14 EKX45135.1 - 0.005 16.3 0.0 6.3 6.1 0.1 3.1 1 1 2 3 3 3 1 Coatomer epsilon subunit ANAPC5 PF12862.7 EKX45135.1 - 0.012 15.7 0.4 24 5.1 0.0 3.8 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 5 DUF3856 PF12968.7 EKX45135.1 - 0.02 14.9 0.3 6.5 6.8 0.0 2.6 2 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_20 PF14561.6 EKX45135.1 - 0.028 14.7 4.2 48 4.4 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 EKX45135.1 - 0.037 14.0 0.0 1.7 8.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L2_C PF03947.18 EKX45136.1 - 3.3e-45 153.4 2.9 5.7e-45 152.6 2.9 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EKX45136.1 - 1.4e-16 60.2 0.0 3.9e-16 58.8 0.0 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Crisp PF08562.10 EKX45138.1 - 7.2 7.3 28.4 5.2 7.7 2.2 4.3 1 1 3 4 4 4 0 Crisp DAGAT PF03982.13 EKX45139.1 - 0.0006 18.8 0.0 0.00077 18.5 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 EKX45139.1 - 0.0032 17.1 0.0 0.0051 16.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Voltage_CLC PF00654.20 EKX45140.1 - 4.3e-64 217.0 11.1 1.4e-59 202.1 4.2 2.9 1 1 2 3 3 3 2 Voltage gated chloride channel CBS PF00571.28 EKX45140.1 - 3e-11 43.6 0.0 0.00015 22.2 0.0 2.6 2 0 0 2 2 2 2 CBS domain HRG PF16954.5 EKX45140.1 - 3 8.3 5.4 38 4.8 1.0 2.9 2 0 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene BET PF17035.5 EKX45141.1 - 6.7e-21 74.2 0.3 1e-20 73.6 0.3 1.3 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Bromodomain PF00439.25 EKX45141.1 - 3.7e-20 71.8 0.0 5.7e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain Glyco_transf_8 PF01501.20 EKX45142.1 - 5.8e-08 32.6 0.3 1.5e-06 28.0 0.5 2.6 2 1 0 2 2 2 1 Glycosyl transferase family 8 Ank_4 PF13637.6 EKX45144.1 - 2.6e-17 62.9 0.1 5.9e-09 36.3 0.0 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX45144.1 - 5.4e-16 59.0 0.1 1.4e-15 57.6 0.1 1.7 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX45144.1 - 2.7e-13 48.8 0.0 2.1e-06 27.6 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EKX45144.1 - 1e-12 47.9 0.0 2.7e-05 24.4 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EKX45144.1 - 5.4e-10 39.3 0.1 0.00012 22.3 0.0 2.3 1 1 0 2 2 2 2 Ankyrin repeats (many copies) KRAB PF01352.27 EKX45144.1 - 0.068 12.8 0.2 3.6 7.3 0.3 3.0 3 0 0 3 3 3 0 KRAB box PHINT_rpt PF14882.6 EKX45147.1 - 0.059 13.6 1.1 0.11 12.8 1.1 1.4 1 0 0 1 1 1 0 Phage-integrase repeat unit Guanylate_cyc PF00211.20 EKX45148.1 - 1.1e-16 60.9 0.0 1.3e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 EKX45149.1 - 6e-22 78.1 0.3 6.6e-22 78.0 0.3 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Yippee-Mis18 PF03226.14 EKX45150.1 - 2.2e-13 50.3 0.7 2.7e-13 50.0 0.7 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SelR PF01641.18 EKX45150.1 - 0.0038 17.3 0.5 0.0055 16.8 0.5 1.2 1 0 0 1 1 1 1 SelR domain RIG-I_C-RD PF11648.8 EKX45150.1 - 0.0065 16.7 0.5 0.0079 16.4 0.5 1.3 1 0 0 1 1 1 1 C-terminal domain of RIG-I Jas PF16135.5 EKX45150.1 - 0.06 13.5 0.3 0.06 13.5 0.3 1.8 1 1 1 2 2 2 0 TPL-binding domain in jasmonate signalling Ribosomal_S13 PF00416.22 EKX45151.1 - 3.1e-51 173.1 4.1 3.6e-51 172.9 4.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF2746 PF10874.8 EKX45151.1 - 0.046 14.1 0.0 0.081 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) HA2 PF04408.23 EKX45152.1 - 1.3e-24 86.5 0.0 2.5e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EKX45152.1 - 2.8e-13 50.2 0.0 6.7e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EKX45152.1 - 4.7e-09 36.5 0.1 2.1e-07 31.2 0.1 2.4 1 1 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold CAP_N PF01213.19 EKX45152.1 - 0.02 14.4 2.2 0.03 13.8 2.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 EKX45152.1 - 0.1 12.6 0.3 0.15 12.1 0.3 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF4030 PF13222.6 EKX45152.1 - 0.13 12.4 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4030) PRIMA1 PF16101.5 EKX45152.1 - 2 8.5 4.9 4.6 7.3 4.9 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 LRR_6 PF13516.6 EKX45153.1 - 2.1e-61 198.8 55.7 2.2e-05 24.2 0.1 18.2 19 0 0 19 19 19 15 Leucine Rich repeat LRR_4 PF12799.7 EKX45153.1 - 6.3e-15 55.1 39.1 0.008 16.6 0.8 11.0 5 5 7 13 13 13 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX45153.1 - 1.5e-10 40.1 10.3 35 5.5 0.0 13.0 15 1 0 15 15 14 0 Leucine Rich Repeat LRR_8 PF13855.6 EKX45153.1 - 1.5e-06 27.9 49.3 0.19 11.5 1.7 11.9 5 4 6 11 11 11 5 Leucine rich repeat LRR_2 PF07723.13 EKX45153.1 - 0.00014 22.3 1.0 36 5.3 0.0 6.4 7 0 0 7 7 5 0 Leucine Rich Repeat SpoU_sub_bind PF08032.12 EKX45153.1 - 0.00053 20.2 0.3 12 6.3 0.0 4.6 5 0 0 5 5 4 1 RNA 2'-O ribose methyltransferase substrate binding Plasmid_parti PF01672.16 EKX45153.1 - 0.0018 18.8 3.5 6.5 7.5 0.0 5.3 4 2 1 5 5 5 1 Putative plasmid partition protein DUF2202 PF09968.9 EKX45153.1 - 0.012 15.4 1.1 13 5.6 0.0 4.0 2 2 3 6 6 6 0 Uncharacterized protein domain (DUF2202) SSURE PF11966.8 EKX45153.1 - 0.056 13.2 0.1 1.4 8.7 0.0 3.1 3 1 0 3 3 3 0 Fibronectin-binding repeat LRR_9 PF14580.6 EKX45153.1 - 0.53 9.8 14.2 4.8 6.6 1.3 4.3 2 2 2 4 4 4 0 Leucine-rich repeat DUF4252 PF14060.6 EKX45153.1 - 2.4 8.0 5.4 3.1 7.7 0.0 3.4 4 1 1 5 5 5 0 Domain of unknown function (DUF4252) EF-hand_1 PF00036.32 EKX45154.1 - 5.2e-24 81.9 12.6 5.5e-06 25.6 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EKX45154.1 - 1.2e-23 80.9 7.1 1.2e-05 24.9 0.0 4.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 EKX45154.1 - 1.7e-20 73.2 11.2 7.3e-11 42.4 0.0 2.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EKX45154.1 - 1.6e-13 49.5 16.4 0.00079 18.8 0.6 4.9 4 1 1 5 5 5 4 EF hand EF-hand_8 PF13833.6 EKX45154.1 - 3.1e-11 42.9 13.1 0.00019 21.2 0.1 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 EKX45154.1 - 5.3e-07 29.9 0.0 0.0017 18.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain Caleosin PF05042.13 EKX45154.1 - 3.1e-05 24.0 0.4 1.6 8.6 0.1 3.0 1 1 2 3 3 3 2 Caleosin related protein Toprim_2 PF13155.6 EKX45154.1 - 0.0026 18.2 0.0 1 9.8 0.0 2.8 1 1 2 3 3 3 1 Toprim-like DUF5640 PF18692.1 EKX45154.1 - 0.016 15.3 0.4 10 6.2 0.0 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5640) Exonuc_VII_S PF02609.16 EKX45154.1 - 0.017 15.2 5.2 7.1 6.8 0.0 3.7 4 0 0 4 4 4 0 Exonuclease VII small subunit Cation_ATPase_N PF00690.26 EKX45154.1 - 0.021 14.5 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus EF-hand_4 PF12763.7 EKX45154.1 - 0.043 13.8 1.2 0.089 12.8 0.1 2.1 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 EKX45154.1 - 0.064 13.6 0.2 8.7 6.8 0.0 2.4 2 1 0 2 2 2 0 EF-hand domain VbhA PF18495.1 EKX45154.1 - 0.11 12.4 0.1 6.1 6.8 0.0 2.9 3 0 0 3 3 3 0 Antitoxin VbhA DUF1456 PF07308.13 EKX45154.1 - 0.12 12.7 0.7 14 6.1 0.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1456) DUF4498 PF14926.6 EKX45155.1 - 4.1e-73 245.7 4.4 4.8e-73 245.5 4.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4498) DUF2299 PF10061.9 EKX45155.1 - 0.036 13.8 0.1 0.079 12.7 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) BRCC36_C PF18110.1 EKX45155.1 - 0.09 12.9 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 BRCC36 C-terminal helical domain CoA_binding_2 PF13380.6 EKX45156.1 - 2.4e-33 115.1 0.4 2.9e-33 114.8 0.4 1.1 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 EKX45156.1 - 6.1e-09 36.5 0.3 9.2e-09 35.9 0.3 1.3 1 0 0 1 1 1 1 CoA binding domain Pox_G7 PF05503.12 EKX45156.1 - 0.06 12.3 0.0 0.082 11.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus G7-like Pkinase_Tyr PF07714.17 EKX45158.1 - 5.1e-13 48.9 0.0 6.1e-13 48.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX45158.1 - 6.2e-12 45.4 0.0 7.1e-12 45.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain WWE PF02825.20 EKX45159.1 - 7.4e-09 36.1 0.0 1.1e-08 35.5 0.0 1.2 1 0 0 1 1 1 1 WWE domain Zn_ribbon_recom PF13408.6 EKX45159.1 - 0.069 13.7 0.8 0.13 12.8 0.8 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain PEX11 PF05648.14 EKX45160.1 - 0.093 12.2 0.0 0.25 10.8 0.0 1.7 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) TRM13 PF05206.14 EKX45160.1 - 0.11 11.9 1.3 0.28 10.7 1.3 1.6 1 0 0 1 1 1 0 Methyltransferase TRM13 DNA_pol_phi PF04931.13 EKX45160.1 - 2.2 6.3 9.9 3.8 5.5 9.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 EKX45160.1 - 3.9 6.7 7.6 1.5 8.1 4.0 2.0 2 0 0 2 2 2 0 NOA36 protein SET PF00856.28 EKX45161.1 - 4.7e-12 46.6 0.0 7.9e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 SET domain HTH_psq PF05225.16 EKX45161.1 - 0.0087 15.8 0.1 0.033 13.9 0.0 1.9 2 0 0 2 2 2 1 helix-turn-helix, Psq domain FKBP_C PF00254.28 EKX45162.1 - 4.5e-32 110.2 0.0 6.7e-32 109.7 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DnaJ PF00226.31 EKX45163.1 - 9.3e-20 70.5 0.5 1.3e-19 70.0 0.5 1.2 1 0 0 1 1 1 1 DnaJ domain DUF493 PF04359.14 EKX45163.1 - 0.11 13.1 0.1 0.18 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF493) PX PF00787.24 EKX45164.1 - 2.3e-08 34.0 0.4 2.3e-08 34.0 0.4 1.9 2 1 0 2 2 2 1 PX domain Rrp15p PF07890.12 EKX45165.1 - 1.3e-21 77.3 13.3 1.3e-21 77.3 13.3 3.1 3 0 0 3 3 3 1 Rrp15p CDC24 PF06395.11 EKX45165.1 - 0.049 13.9 0.7 0.18 12.1 0.1 2.1 2 0 0 2 2 2 0 CDC24 Calponin TFIIA PF03153.13 EKX45165.1 - 4.6 7.1 33.5 6.7 6.6 33.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Snf7 PF03357.21 EKX45166.1 - 3.5e-14 52.8 26.1 3.5e-14 52.8 26.1 1.6 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.14 EKX45166.1 - 0.04 13.9 10.9 0.092 12.7 10.9 1.6 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway DUF2894 PF11445.8 EKX45166.1 - 0.2 12.1 5.9 0.075 13.5 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2894) Cytochrom_B562 PF07361.11 EKX45166.1 - 0.89 10.2 17.6 0.15 12.8 7.7 2.5 2 0 0 2 2 2 0 Cytochrome b562 TBCA PF02970.16 EKX45166.1 - 6.4 7.2 20.5 0.036 14.4 8.6 2.8 1 1 2 3 3 3 0 Tubulin binding cofactor A Mt_ATP-synt_D PF05873.12 EKX45166.1 - 7.2 6.4 14.4 0.83 9.5 1.7 2.5 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) IFT46_B_C PF12317.8 EKX45166.1 - 7.4 6.2 14.7 32 4.2 0.5 2.9 1 1 2 3 3 3 0 Intraflagellar transport complex B protein 46 C terminal Sigma70_r4_2 PF08281.12 EKX45167.1 - 0.013 15.2 0.0 0.049 13.3 0.0 2.0 1 0 0 1 1 1 0 Sigma-70, region 4 DUF1719 PF08224.11 EKX45167.1 - 0.13 11.3 0.2 6.5 5.8 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1719) ZapD PF07072.11 EKX45167.1 - 0.17 11.6 5.1 0.25 11.1 3.5 2.0 1 1 0 1 1 1 0 Cell division protein TEX13 PF15186.6 EKX45167.1 - 0.18 11.5 6.0 0.14 11.9 3.1 2.1 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family V_ATPase_I PF01496.19 EKX45167.1 - 0.63 7.9 2.6 1.7 6.4 1.9 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF4162 PF13732.6 EKX45167.1 - 1.1 10.0 5.8 11 6.8 3.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) BMFP PF04380.13 EKX45167.1 - 1.3 9.6 8.3 4.6 7.8 0.2 3.1 3 0 0 3 3 3 0 Membrane fusogenic activity MCU PF04678.13 EKX45167.1 - 2.2 8.3 7.6 0.44 10.6 3.3 1.9 2 1 0 2 2 2 0 Mitochondrial calcium uniporter TPR_12 PF13424.6 EKX45168.1 - 4e-107 350.6 36.4 5.6e-18 65.0 0.1 7.6 1 1 7 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.6 EKX45168.1 - 2e-94 307.2 3.9 1.9e-12 46.6 0.0 8.2 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_7 PF13176.6 EKX45168.1 - 8.5e-37 122.5 22.5 0.00021 21.1 0.5 8.5 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_1 PF00515.28 EKX45168.1 - 4.3e-32 108.6 24.9 0.0009 19.0 0.1 8.3 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_2 PF07719.17 EKX45168.1 - 3e-27 92.5 17.9 0.0014 18.6 0.0 8.7 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.6 EKX45168.1 - 1.7e-23 83.0 0.7 0.00012 22.7 0.0 8.4 3 3 5 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 EKX45168.1 - 2.2e-23 80.5 21.8 0.0014 18.7 0.1 8.2 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_19 PF14559.6 EKX45168.1 - 6.9e-14 52.1 7.6 0.025 15.1 0.5 6.6 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 EKX45168.1 - 3.2e-12 45.9 6.7 4.9 7.8 0.1 8.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX45168.1 - 1.2e-11 44.4 8.0 3.7 8.6 0.0 7.9 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX45168.1 - 1.7e-09 37.5 0.9 0.0016 17.8 0.0 3.2 1 1 2 3 3 3 3 MalT-like TPR region TPR_3 PF07720.12 EKX45168.1 - 4.1e-09 36.2 19.3 0.13 12.3 0.0 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_20 PF14561.6 EKX45168.1 - 8.1e-09 35.7 0.9 2.4 8.5 0.1 7.0 3 2 5 8 8 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX45168.1 - 1.3e-08 35.0 8.5 0.65 10.3 0.1 5.4 4 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 EKX45168.1 - 1.6e-07 31.1 9.0 0.1 12.9 0.2 6.1 6 0 0 6 6 6 3 PPR repeat TPR_4 PF07721.14 EKX45168.1 - 1.6e-05 25.1 0.0 10 7.1 0.0 6.2 7 0 0 7 7 5 0 Tetratricopeptide repeat RPN6_N PF18055.1 EKX45168.1 - 0.00012 22.5 0.1 12 6.3 0.0 4.2 2 2 0 4 4 4 0 26S proteasome regulatory subunit RPN6 N-terminal domain PPR_2 PF13041.6 EKX45168.1 - 0.00014 21.9 1.3 3.9 7.7 0.0 6.3 8 0 0 8 8 8 1 PPR repeat family SNAP PF14938.6 EKX45168.1 - 0.0026 17.3 2.9 9.9 5.5 0.0 4.9 1 1 1 4 4 4 0 Soluble NSF attachment protein, SNAP MIT PF04212.18 EKX45168.1 - 0.0042 17.1 23.1 1.8 8.7 0.1 6.9 6 2 2 8 8 8 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 EKX45168.1 - 0.0067 17.0 14.4 17 6.3 0.0 7.9 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF1897 PF09005.10 EKX45168.1 - 0.034 13.6 8.8 13 5.4 0.1 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF1897) TPR_11 PF13414.6 EKX45168.1 - 0.54 10.0 22.5 24 4.7 0.3 6.5 6 0 0 6 6 6 0 TPR repeat BAH PF01426.18 EKX45169.1 - 0.078 12.8 0.6 0.13 12.1 0.6 1.3 1 0 0 1 1 1 0 BAH domain Leu_zip PF15294.6 EKX45169.1 - 0.15 11.6 13.6 0.068 12.7 4.2 2.2 1 1 0 2 2 2 0 Leucine zipper NAP PF00956.18 EKX45169.1 - 1.1 8.4 5.5 1.1 8.4 3.1 2.0 2 0 0 2 2 2 0 Nucleosome assembly protein (NAP) COG2 PF06148.11 EKX45169.1 - 1.4 9.0 6.6 0.96 9.5 4.0 2.1 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF334 PF03904.13 EKX45169.1 - 1.9 8.0 5.4 4.9 6.6 5.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF334) dsRBD2 PF17842.1 EKX45169.1 - 9.4 6.4 12.2 1.6 8.9 3.1 2.9 3 0 0 3 3 3 0 Double-stranded RNA binding domain 2 DUF4200 PF13863.6 EKX45169.1 - 9.4 6.7 15.6 2 8.8 11.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Ndc80_HEC PF03801.13 EKX45170.1 - 5.3e-42 143.0 1.5 5.9e-42 142.9 0.6 1.5 1 1 0 1 1 1 1 HEC/Ndc80p family DUF5595 PF18077.1 EKX45170.1 - 1.5e-11 44.2 5.2 2.9e-11 43.3 5.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5595) DUF4936 PF16290.5 EKX45170.1 - 0.024 15.3 0.1 0.15 12.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4936) Cluap1 PF10234.9 EKX45170.1 - 0.11 11.8 0.0 0.11 11.8 0.0 2.7 2 1 1 3 3 3 0 Clusterin-associated protein-1 DivIC PF04977.15 EKX45170.1 - 0.35 10.6 3.9 0.64 9.8 3.2 1.8 1 1 0 1 1 1 0 Septum formation initiator GTP_EFTU PF00009.27 EKX45171.1 - 1.8e-36 125.5 0.0 2.2e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EKX45171.1 - 9.8e-23 80.6 0.0 2.1e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EKX45171.1 - 0.0015 18.9 0.0 0.0034 17.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EKX45171.1 - 0.012 15.6 0.0 0.074 13.1 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EKX45172.1 - 2.5e-26 92.4 0.0 3.4e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EKX45172.1 - 1.8e-22 79.7 0.0 4.1e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EKX45172.1 - 0.012 16.0 0.0 0.027 14.9 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 2 DJ-1_PfpI PF01965.24 EKX45173.1 - 4.2e-42 143.8 0.6 4.7e-42 143.6 0.6 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EKX45173.1 - 0.015 15.0 0.1 1.4 8.6 0.1 2.6 1 1 1 2 2 2 0 ThiJ/PfpI family-like Pyr_redox_2 PF07992.14 EKX45174.1 - 9e-31 107.2 0.0 1.2e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EKX45174.1 - 9.8e-09 35.7 0.0 3.6e-06 27.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EKX45174.1 - 6e-07 29.6 0.0 0.059 13.6 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EKX45174.1 - 2e-06 27.6 0.0 0.047 13.3 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EKX45174.1 - 1.7e-05 24.2 0.0 0.00027 20.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EKX45174.1 - 2.8e-05 24.1 0.0 0.15 12.1 0.0 3.8 3 1 1 4 4 4 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 EKX45174.1 - 7.5e-05 22.1 0.0 0.077 12.2 0.0 2.4 3 0 0 3 3 3 2 FAD binding domain TrkA_N PF02254.18 EKX45174.1 - 0.00087 19.5 0.0 0.09 13.0 0.0 2.3 2 0 0 2 2 2 1 TrkA-N domain DUF1188 PF06690.11 EKX45174.1 - 0.00099 18.7 0.0 0.14 11.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1188) Lycopene_cycl PF05834.12 EKX45174.1 - 0.0016 17.6 0.0 0.0068 15.5 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein K_oxygenase PF13434.6 EKX45174.1 - 0.0016 17.6 0.0 0.0098 15.1 0.0 2.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 EKX45174.1 - 0.0042 17.5 0.0 0.61 10.6 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 EKX45174.1 - 0.01 15.1 0.0 4.2 6.5 0.1 2.2 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.14 EKX45174.1 - 0.012 14.3 0.0 0.17 10.5 0.0 2.3 2 0 0 2 2 2 0 HI0933-like protein zf-CCHC PF00098.23 EKX45175.1 - 3.6e-13 48.9 30.9 2.7e-06 27.2 2.9 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-C2H2_10 PF16588.5 EKX45175.1 - 0.00011 21.8 19.0 0.083 12.6 3.4 3.4 3 0 0 3 3 3 3 C2H2 zinc-finger zf-CCHC_2 PF13696.6 EKX45175.1 - 0.0015 18.3 4.0 0.0015 18.3 4.0 4.6 4 1 0 4 4 4 2 Zinc knuckle zf-CCHC_3 PF13917.6 EKX45175.1 - 0.012 15.6 1.2 0.012 15.6 1.2 4.0 1 1 3 4 4 4 0 Zinc knuckle zf-CCHC_4 PF14392.6 EKX45175.1 - 0.013 15.3 0.9 0.013 15.3 0.9 4.0 4 0 0 4 4 4 0 Zinc knuckle PPR_2 PF13041.6 EKX45176.1 - 1.3e-38 130.9 0.9 8.6e-16 57.9 0.2 4.4 1 1 3 4 4 4 4 PPR repeat family PPR_3 PF13812.6 EKX45176.1 - 1.5e-27 95.4 0.0 8e-13 48.3 0.0 3.1 1 1 2 3 3 3 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 EKX45176.1 - 6.7e-25 86.5 0.3 1.2e-10 40.9 0.1 3.4 3 0 0 3 3 3 3 PPR repeat PPR PF01535.20 EKX45176.1 - 1.6e-24 84.3 0.9 5.2e-08 32.6 0.1 4.7 4 0 0 4 4 4 3 PPR repeat Methyltransf_4 PF02390.17 EKX45176.1 - 2.6e-19 69.4 0.0 6.9e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase PPR_long PF17177.4 EKX45176.1 - 3.1e-10 39.8 0.0 5.7e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP MTS PF05175.14 EKX45176.1 - 0.0029 17.2 0.1 0.65 9.5 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase small domain Ribosomal_L30_N PF08079.12 EKX45177.1 - 1.2e-09 38.3 9.5 2.2e-09 37.4 9.5 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 EKX45177.1 - 1.5e-09 37.6 0.1 4.8e-09 36.0 0.1 1.9 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Methyltransf_25 PF13649.6 EKX45178.1 - 4.1e-07 30.6 0.1 8.4e-07 29.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX45178.1 - 1.9e-06 27.7 0.1 2.7e-06 27.2 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX45178.1 - 5.6e-06 26.9 0.0 1.3e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX45178.1 - 0.0005 20.8 0.1 0.006 17.3 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain NodS PF05401.11 EKX45178.1 - 0.0011 18.6 0.1 0.0014 18.3 0.1 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_23 PF13489.6 EKX45178.1 - 0.041 13.7 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain RRM_1 PF00076.22 EKX45179.1 - 1.6e-22 79.1 0.0 2.1e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EKX45179.1 - 0.0033 17.5 0.0 0.0062 16.6 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 EKX45179.1 - 0.027 14.5 0.0 0.041 13.9 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Ank_3 PF13606.6 EKX45180.1 - 3.4e-10 39.3 0.6 1.2e-06 28.4 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EKX45180.1 - 1.8e-08 34.5 0.8 5.3e-06 26.6 0.2 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EKX45180.1 - 2.2e-08 34.5 0.2 1.8e-07 31.5 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX45180.1 - 1.8e-07 31.6 0.2 3e-07 30.9 0.2 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX45180.1 - 8.2e-06 26.0 0.9 0.00076 19.7 0.2 1.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) HECW1_helix PF18436.1 EKX45181.1 - 0.04 14.0 0.0 0.077 13.1 0.0 1.4 1 0 0 1 1 1 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 EF-hand_1 PF00036.32 EKX45182.1 - 1.8e-17 61.5 4.1 9e-05 21.8 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EKX45182.1 - 4e-15 54.4 3.3 6.1e-05 22.6 0.0 4.1 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 EKX45182.1 - 7.2e-14 50.6 4.5 0.0004 19.7 0.2 3.8 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EKX45182.1 - 5.8e-13 49.1 4.0 2.6e-07 31.0 0.2 2.7 2 1 0 2 2 2 2 EF-hand domain pair WW PF00397.26 EKX45182.1 - 5.4e-12 45.6 1.1 1e-11 44.7 1.1 1.5 1 0 0 1 1 1 1 WW domain EF-hand_8 PF13833.6 EKX45182.1 - 4e-09 36.2 0.8 0.025 14.4 0.0 3.9 3 0 0 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX45182.1 - 0.00065 20.0 0.4 0.17 12.2 0.1 2.8 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Glyco_hyd_101C PF17451.2 EKX45182.1 - 0.023 15.0 0.7 0.061 13.6 0.7 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain EF-hand_10 PF14788.6 EKX45182.1 - 0.59 10.0 4.3 1.6 8.6 0.1 3.0 3 0 0 3 3 3 0 EF hand UPF0175 PF03683.13 EKX45183.1 - 0.15 11.8 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) Allantoicase PF03561.15 EKX45184.1 - 9.2e-82 272.1 0.0 1.1e-43 148.7 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat NiFe_hyd_SSU_C PF14720.6 EKX45184.1 - 0.0065 16.8 0.0 2.3 8.7 0.0 2.4 2 0 0 2 2 2 2 NiFe/NiFeSe hydrogenase small subunit C-terminal RRM_1 PF00076.22 EKX45185.1 - 3.1e-25 87.8 0.0 2.1e-14 53.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EKX45185.1 - 1.8e-07 31.2 0.3 0.0057 16.7 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif C2 PF00168.30 EKX45186.1 - 9.9e-20 70.8 3.3 3.6e-05 24.0 0.0 4.6 5 0 0 5 5 5 3 C2 domain Ribosomal_S30AE PF02482.19 EKX45188.1 - 5e-23 81.7 0.5 7.1e-23 81.2 0.5 1.2 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein Ribosom_S30AE_C PF16321.5 EKX45188.1 - 2.9e-20 71.7 0.1 5.4e-20 70.8 0.1 1.5 1 0 0 1 1 1 1 Sigma 54 modulation/S30EA ribosomal protein C terminus VitD-bind_III PF09164.10 EKX45188.1 - 0.039 13.9 0.4 2.7 8.1 0.1 2.5 2 0 0 2 2 2 0 Vitamin D binding protein, domain III T4_Rnl2_C PF18043.1 EKX45188.1 - 0.098 12.8 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 T4 RNA ligase 2 C-terminal Arm PF00514.23 EKX45189.1 - 4.8e-07 29.6 1.0 0.16 12.0 0.1 4.5 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat E3_UbLigase_R4 PF13764.6 EKX45189.1 - 0.0013 17.0 0.3 0.0041 15.4 0.3 1.7 1 1 0 1 1 1 1 E3 ubiquitin-protein ligase UBR4 Zn-C2H2_12 PF18112.1 EKX45190.1 - 0.017 15.6 0.2 0.038 14.5 0.2 1.5 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_4 PF13894.6 EKX45190.1 - 0.059 14.2 2.0 4.8 8.3 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Ank_2 PF12796.7 EKX45191.1 - 8.6e-07 29.5 0.0 2.9e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX45191.1 - 0.00029 21.3 0.0 0.37 11.4 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX45191.1 - 0.01 16.3 0.1 6.8 7.6 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat Guanylate_cyc PF00211.20 EKX45192.1 - 1.3e-46 158.6 0.2 1.5e-46 158.3 0.2 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 EKX45193.1 - 1.5e-49 168.7 0.0 1.8e-49 168.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX45193.1 - 1.2e-43 149.4 0.0 1.5e-43 149.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EKX45193.1 - 4.8e-05 22.3 0.0 7e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EKX45193.1 - 0.0019 17.3 0.0 0.0035 16.5 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 EKX45193.1 - 0.0029 17.6 0.1 0.0046 16.9 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family SBF PF01758.16 EKX45194.1 - 5.7e-37 127.3 20.4 9.2e-37 126.6 20.4 1.3 1 0 0 1 1 1 1 Sodium Bile acid symporter family UVR PF02151.19 EKX45195.1 - 0.026 14.2 1.5 0.074 12.8 1.5 1.7 1 0 0 1 1 1 0 UvrB/uvrC motif adh_short PF00106.25 EKX45196.1 - 6.7e-39 133.4 0.0 8e-39 133.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EKX45196.1 - 1.7e-22 80.2 0.0 1.9e-22 80.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX45196.1 - 3.2e-09 36.9 0.2 3.9e-09 36.7 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EKX45196.1 - 0.00042 19.8 0.0 0.00057 19.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EKX45196.1 - 0.0031 16.7 0.0 0.0043 16.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain THF_DHG_CYH_C PF02882.19 EKX45196.1 - 0.0076 15.6 0.6 0.018 14.3 0.1 1.9 2 1 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ADH_zinc_N PF00107.26 EKX45196.1 - 0.017 15.1 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 EKX45196.1 - 0.032 14.1 0.3 0.044 13.7 0.3 1.5 1 1 0 1 1 1 0 NAD(P)H-binding ApbA PF02558.16 EKX45196.1 - 0.18 11.4 0.1 0.3 10.7 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Polysacc_synt_2 PF02719.15 EKX45196.1 - 0.21 10.7 0.0 0.27 10.3 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Aminotran_4 PF01063.19 EKX45197.1 - 0.11 12.4 0.3 0.17 11.7 0.3 1.3 1 0 0 1 1 1 0 Amino-transferase class IV WW PF00397.26 EKX45198.1 - 1.3e-08 34.7 1.1 2e-08 34.1 1.1 1.3 1 0 0 1 1 1 1 WW domain RyR PF02026.16 EKX45198.1 - 0.063 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 RyR domain Ufd2P_core PF10408.9 EKX45199.1 - 6.7e-87 292.6 2.9 7.9e-87 292.3 2.9 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 EKX45199.1 - 7.4e-21 74.1 1.8 2.7e-20 72.3 1.2 2.2 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.8 EKX45199.1 - 0.098 12.5 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit WD40 PF00400.32 EKX45200.1 - 0.0025 18.6 7.2 0.3 12.0 0.5 4.7 4 1 0 4 4 4 2 WD domain, G-beta repeat Zip PF02535.22 EKX45202.1 - 2.4e-30 105.9 11.8 3.6e-30 105.3 11.8 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Gly-zipper_YMGG PF13441.6 EKX45202.1 - 0.097 12.4 1.1 0.47 10.2 0.2 2.0 1 1 1 2 2 2 0 YMGG-like Gly-zipper SPC12 PF06645.13 EKX45202.1 - 0.87 9.7 3.7 0.29 11.3 0.6 1.8 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Cpn60_TCP1 PF00118.24 EKX45203.1 - 4.2e-147 490.7 13.6 4.8e-147 490.5 13.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.17 EKX45203.1 - 0.014 15.7 0.5 0.24 11.7 0.1 2.9 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor Yippee-Mis18 PF03226.14 EKX45204.1 - 5.9e-12 45.7 0.3 7.4e-12 45.4 0.3 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Cytochrome_C7 PF14522.6 EKX45204.1 - 0.0038 17.2 1.5 1.5 8.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome c7 and related cytochrome c zf-CHY PF05495.12 EKX45204.1 - 0.0093 16.4 1.7 0.31 11.6 0.1 2.1 2 0 0 2 2 2 1 CHY zinc finger Jas PF16135.5 EKX45204.1 - 0.063 13.5 0.4 0.063 13.5 0.4 1.9 1 1 0 2 2 2 0 TPL-binding domain in jasmonate signalling CCP_MauG PF03150.14 EKX45204.1 - 0.7 10.5 3.6 8.1 7.1 0.6 2.1 1 1 1 2 2 2 0 Di-haem cytochrome c peroxidase TIG PF01833.24 EKX45205.1 - 4.1e-24 84.4 16.1 1.8e-11 43.9 0.4 4.9 6 0 0 6 6 6 3 IPT/TIG domain EGF_2 PF07974.13 EKX45205.1 - 6.7e-06 26.4 32.3 0.00023 21.4 12.2 6.0 6 0 0 6 6 6 2 EGF-like domain hEGF PF12661.7 EKX45205.1 - 0.0011 19.6 32.3 0.013 16.1 9.0 5.8 4 0 0 4 4 4 2 Human growth factor-like EGF Ephrin_rec_like PF07699.13 EKX45205.1 - 0.0015 18.3 1.3 0.0015 18.3 1.3 4.6 4 0 0 4 4 4 2 Putative ephrin-receptor like EGF_Tenascin PF18720.1 EKX45205.1 - 0.0024 17.9 32.3 0.0025 17.8 8.7 3.7 3 0 0 3 3 3 2 Tenascin EGF domain AA_kinase PF00696.28 EKX45206.1 - 1.3e-39 136.2 0.1 4.6e-38 131.2 0.0 2.3 2 0 0 2 2 2 2 Amino acid kinase family PA14 PF07691.12 EKX45208.1 - 1e-21 77.3 0.0 3.3e-10 39.9 0.0 2.6 2 0 0 2 2 2 2 PA14 domain Filamin PF00630.19 EKX45208.1 - 2.7e-11 44.2 0.3 0.00026 21.8 0.0 2.5 2 0 0 2 2 2 2 Filamin/ABP280 repeat TIG PF01833.24 EKX45208.1 - 4.1e-08 33.2 4.7 0.00057 19.9 0.7 3.9 2 1 0 3 3 3 2 IPT/TIG domain Invasin_D3 PF09134.10 EKX45208.1 - 0.00016 21.9 0.8 0.71 10.2 0.3 2.6 2 0 0 2 2 2 2 Invasin, domain 3 GLEYA PF10528.9 EKX45208.1 - 0.0067 16.8 0.1 1.1 9.7 0.0 3.5 2 2 0 2 2 2 1 GLEYA domain Topo-VIb_trans PF09239.11 EKX45208.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Topoisomerase VI B subunit, transducer Filamin PF00630.19 EKX45209.1 - 1.5e-16 61.1 2.8 0.29 12.0 0.1 7.5 6 2 0 6 6 6 6 Filamin/ABP280 repeat PA14 PF07691.12 EKX45209.1 - 3.5e-16 59.3 0.2 1.8e-05 24.6 0.0 4.1 4 1 0 4 4 4 3 PA14 domain Big_1 PF02369.16 EKX45209.1 - 0.00072 19.5 3.2 15 5.7 0.0 5.1 5 0 0 5 5 5 2 Bacterial Ig-like domain (group 1) MG2 PF01835.19 EKX45209.1 - 0.0064 16.9 0.0 0.025 15.0 0.0 2.0 1 0 0 1 1 1 1 MG2 domain DUF824 PF05688.11 EKX45209.1 - 0.0067 16.2 0.0 0.13 12.1 0.0 2.7 3 0 0 3 3 3 1 Salmonella repeat of unknown function (DUF824) GLEYA PF10528.9 EKX45209.1 - 0.021 15.2 10.3 6.9 7.2 0.0 4.4 5 0 0 5 5 5 0 GLEYA domain CBM60 PF16841.5 EKX45209.1 - 0.086 13.3 0.0 0.8 10.2 0.0 2.6 2 0 0 2 2 2 0 Ca-dependent carbohydrate-binding module xylan-binding APG6_N PF17675.1 EKX45210.1 - 0.00061 20.3 4.6 0.00094 19.7 4.6 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region Uds1 PF15456.6 EKX45210.1 - 0.013 15.7 1.1 0.024 14.8 1.1 1.4 1 0 0 1 1 1 0 Up-regulated During Septation DASH_Spc19 PF08287.11 EKX45210.1 - 0.022 14.7 2.9 0.023 14.6 2.9 1.2 1 0 0 1 1 1 0 Spc19 Spc7 PF08317.11 EKX45210.1 - 0.026 13.4 2.9 0.04 12.8 2.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein PspA_IM30 PF04012.12 EKX45210.1 - 0.027 14.1 5.8 0.052 13.1 5.8 1.4 1 0 0 1 1 1 0 PspA/IM30 family GAS PF13851.6 EKX45210.1 - 0.029 13.7 4.7 0.048 13.0 4.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TSC22 PF01166.18 EKX45210.1 - 0.039 14.3 2.9 0.043 14.1 1.6 1.7 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF4315 PF14193.6 EKX45210.1 - 0.042 13.8 4.1 0.042 13.8 4.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) G_path_suppress PF15991.5 EKX45210.1 - 0.066 13.3 3.4 0.088 12.9 3.4 1.2 1 0 0 1 1 1 0 G-protein pathway suppressor ORF6C PF10552.9 EKX45210.1 - 0.12 12.4 1.3 0.21 11.7 1.3 1.3 1 0 0 1 1 1 0 ORF6C domain COG2 PF06148.11 EKX45210.1 - 0.19 11.8 3.4 0.31 11.1 2.0 1.8 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Prefoldin_2 PF01920.20 EKX45210.1 - 0.4 10.7 8.0 0.81 9.7 8.0 1.5 1 0 0 1 1 1 0 Prefoldin subunit Ubiquitin_2 PF14560.6 EKX45211.1 - 0.0097 16.3 0.9 0.034 14.6 0.9 1.9 1 0 0 1 1 1 1 Ubiquitin-like domain ZnuA PF01297.17 EKX45211.1 - 0.78 9.1 5.3 1.3 8.4 4.6 1.7 1 1 0 1 1 1 0 Zinc-uptake complex component A periplasmic SET PF00856.28 EKX45212.1 - 4e-12 46.8 0.0 7e-11 42.8 0.0 2.5 2 1 0 2 2 2 1 SET domain DUF2066 PF09839.9 EKX45212.1 - 0.081 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) Ank_2 PF12796.7 EKX45213.1 - 6.3e-28 97.2 0.1 1e-14 54.9 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX45213.1 - 9.8e-23 80.2 2.9 1.1e-11 44.9 0.1 3.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX45213.1 - 3.3e-19 67.0 0.2 0.00023 21.4 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 EKX45213.1 - 6e-19 67.6 0.1 6e-06 26.5 0.0 5.6 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EKX45213.1 - 1.8e-17 63.2 0.3 3.7e-07 30.3 0.0 4.3 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Radial_spoke_3 PF06098.11 EKX45214.1 - 3.1e-72 243.3 5.6 3.1e-72 243.3 5.6 2.0 1 1 1 2 2 2 1 Radial spoke protein 3 Herpes_UL52 PF03121.15 EKX45214.1 - 0.055 13.4 0.2 0.11 12.5 0.2 1.4 1 0 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase THUMP PF02926.17 EKX45218.1 - 2.3e-05 24.5 1.0 0.048 13.8 0.1 2.2 1 1 1 2 2 2 2 THUMP domain GRDP-like PF07173.12 EKX45218.1 - 0.12 13.1 0.0 0.2 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycine-rich domain-containing protein-like Pkinase PF00069.25 EKX45219.1 - 2.7e-43 148.2 0.0 3.9e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX45219.1 - 1.6e-18 66.9 0.1 2.3e-18 66.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX45219.1 - 0.013 15.5 0.1 0.072 13.0 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 EKX45219.1 - 0.042 13.4 0.6 0.08 12.5 0.1 1.8 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 EKX45219.1 - 1.2 8.5 4.9 0.2 11.0 0.3 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3719 PF12516.8 EKX45223.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3719) DUF3456 PF11938.8 EKX45224.1 - 7.3e-14 52.6 8.4 3.6e-13 50.3 8.4 2.0 1 1 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP DUF3552 PF12072.8 EKX45224.1 - 0.49 9.8 7.3 0.76 9.2 2.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Yae1_N PF09811.9 EKX45225.1 - 4.5e-06 26.3 10.9 0.0023 17.6 0.6 3.9 3 1 1 4 4 4 3 Essential protein Yae1, N terminal Shisa PF13908.6 EKX45225.1 - 0.002 18.4 0.1 0.0054 17.0 0.1 1.7 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator CD20 PF04103.15 EKX45225.1 - 0.02 15.0 12.6 0.051 13.7 9.5 2.3 2 0 0 2 2 2 0 CD20-like family DUF1218 PF06749.12 EKX45225.1 - 6.9 7.3 7.6 16 6.1 0.1 3.0 2 1 2 4 4 4 0 Protein of unknown function (DUF1218) Yae1_N PF09811.9 EKX45226.1 - 0.00071 19.2 16.9 0.23 11.2 7.1 4.6 2 2 0 2 2 2 2 Essential protein Yae1, N terminal zf-TRM13_CCCH PF11722.8 EKX45226.1 - 0.21 11.4 0.6 0.44 10.3 0.6 1.5 1 0 0 1 1 1 0 CCCH zinc finger in TRM13 protein DUF5472 PF17566.2 EKX45226.1 - 0.44 10.5 3.5 0.67 10.0 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5472) LysM PF01476.20 EKX45227.1 - 2.8e-05 24.1 0.0 0.003 17.6 0.1 2.5 2 0 0 2 2 2 2 LysM domain Laminin_G_3 PF13385.6 EKX45227.1 - 3.1e-05 24.2 0.4 0.11 12.7 0.0 2.8 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily PDZ_6 PF17820.1 EKX45228.1 - 3.3e-05 23.7 0.0 5.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX45228.1 - 5.8e-05 23.3 0.0 7.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX45228.1 - 0.019 15.0 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Tricorn protease PDZ domain PDZ PF00595.24 EKX45228.1 - 0.11 12.8 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 PDZ domain LRR_9 PF14580.6 EKX45229.1 - 9.2e-17 61.1 0.2 4.8e-11 42.5 0.0 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 EKX45229.1 - 5.9e-16 58.3 11.3 7.6e-05 23.0 0.1 4.7 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) IQ PF00612.27 EKX45229.1 - 1.2e-08 33.9 10.4 0.00024 20.6 0.1 3.8 3 0 0 3 3 3 3 IQ calmodulin-binding motif LRR_8 PF13855.6 EKX45229.1 - 2e-07 30.7 14.3 0.0096 15.7 0.8 3.8 1 1 3 4 4 4 3 Leucine rich repeat zf_UBZ PF18439.1 EKX45229.1 - 0.087 12.4 0.8 0.22 11.1 0.8 1.7 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Csm1_N PF18504.1 EKX45229.1 - 0.12 12.8 2.0 3.5 8.0 0.4 2.5 2 0 0 2 2 2 0 Csm1 N-terminal domain betaPIX_CC PF16523.5 EKX45229.1 - 0.23 11.3 1.7 0.42 10.5 0.1 2.1 2 0 0 2 2 2 0 betaPIX coiled coil LRR_1 PF00560.33 EKX45229.1 - 0.27 11.9 9.5 60 4.8 0.8 5.4 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 EKX45229.1 - 3.1 8.1 9.0 95 3.5 0.5 5.3 6 0 0 6 6 6 0 Leucine Rich repeat CS PF04969.16 EKX45230.1 - 1e-10 42.5 2.7 3.5e-10 40.7 2.7 2.0 1 1 0 1 1 1 1 CS domain Nudc_N PF14050.6 EKX45230.1 - 9.8e-07 28.7 0.3 4.9e-06 26.4 0.5 2.1 2 0 0 2 2 2 1 N-terminal conserved domain of Nudc. CDC45 PF02724.14 EKX45230.1 - 0.93 7.7 9.3 1.5 7.1 9.3 1.4 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 EKX45230.1 - 1.4 7.6 8.4 2.3 6.9 8.4 1.3 1 0 0 1 1 1 0 Presenilin Transthyretin PF00576.21 EKX45231.1 - 5.7e-36 123.6 0.0 6.3e-36 123.4 0.0 1.0 1 0 0 1 1 1 1 HIUase/Transthyretin family Ion_trans PF00520.31 EKX45232.1 - 7.9e-40 136.6 10.1 1.1e-39 136.2 10.1 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX45232.1 - 1.7e-10 40.7 9.4 1.7e-10 40.7 9.4 2.8 2 1 0 2 2 2 1 Ion channel MSP1a PF11670.8 EKX45232.1 - 0.015 14.6 0.1 2.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Major surface protein 1a (MSP1a) HCR PF07111.12 EKX45232.1 - 0.027 12.6 0.2 0.039 12.0 0.2 1.1 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) CRAL_TRIO PF00650.20 EKX45233.1 - 1.1e-24 87.0 0.1 1.6e-24 86.4 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EKX45233.1 - 3.5e-06 27.2 0.0 6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain GST_C PF00043.25 EKX45234.1 - 6.9e-12 45.4 0.0 1.3e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EKX45234.1 - 4.4e-11 43.0 0.0 2.6e-10 40.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EKX45234.1 - 3.3e-10 39.8 0.1 9.5e-10 38.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EKX45234.1 - 5.4e-09 36.2 0.0 1.1e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EKX45234.1 - 3.3e-08 33.7 0.0 6.4e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EKX45234.1 - 1.5e-06 28.5 0.0 2.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain CcmH PF03918.14 EKX45234.1 - 0.01 15.1 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C biogenesis protein GST_C_5 PF16865.5 EKX45234.1 - 0.023 15.3 0.0 0.035 14.7 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EKX45234.1 - 0.043 13.6 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FtsJ PF01728.19 EKX45235.1 - 2.3e-67 226.5 0.1 2.7e-67 226.3 0.1 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 EKX45235.1 - 0.019 14.8 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 EKX45235.1 - 0.022 14.4 0.0 0.046 13.4 0.0 1.5 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Acetyltransf_1 PF00583.25 EKX45236.1 - 2.5e-18 66.4 0.0 3e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EKX45236.1 - 2.4e-11 43.9 0.1 3.1e-11 43.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EKX45236.1 - 9e-11 41.8 0.0 1.2e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EKX45236.1 - 1.1e-08 35.0 0.0 1.5e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 EKX45236.1 - 4.9e-06 26.3 0.0 6.1e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EKX45236.1 - 0.00073 20.2 0.0 0.00086 20.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EKX45236.1 - 0.0047 17.0 0.1 0.0089 16.1 0.0 1.5 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.7 EKX45236.1 - 0.025 14.7 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EKX45236.1 - 0.028 14.5 0.0 0.048 13.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain ERAP1_C PF11838.8 EKX45236.1 - 0.092 12.3 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 ERAP1-like C-terminal domain AMP-binding PF00501.28 EKX45237.1 - 5.5e-67 226.2 1.6 2.9e-65 220.5 1.6 2.0 1 1 0 1 1 1 1 AMP-binding enzyme IF-2B PF01008.17 EKX45238.1 - 2.3e-74 250.1 0.1 2.7e-74 249.9 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family TM1506 PF08973.10 EKX45238.1 - 0.1 12.3 1.9 0.18 11.5 0.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1893) AAA_6 PF12774.7 EKX45239.1 - 6e-152 505.3 0.0 1.2e-149 497.8 0.0 3.4 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EKX45239.1 - 2.3e-133 445.2 11.1 2.3e-133 445.2 11.1 2.8 3 0 0 3 3 2 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 EKX45239.1 - 6.9e-103 344.1 3.0 1.1e-102 343.3 0.3 2.8 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 EKX45239.1 - 1e-101 339.6 0.0 1e-101 339.6 0.0 2.7 4 0 0 4 4 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EKX45239.1 - 6.5e-88 293.5 0.5 6.6e-87 290.2 0.6 2.9 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 EKX45239.1 - 1.1e-79 266.1 1.4 2.4e-75 252.0 0.0 3.7 4 0 0 4 4 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EKX45239.1 - 4.1e-56 189.3 0.0 1.1e-55 187.9 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 EKX45239.1 - 3.4e-52 177.6 7.0 8.2e-52 176.3 7.0 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EKX45239.1 - 2.2e-43 147.1 0.0 3.1e-41 140.2 0.0 3.3 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EKX45239.1 - 3.3e-29 101.6 0.1 1.6e-28 99.4 0.1 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EKX45239.1 - 2e-17 63.2 0.0 8.9e-17 61.1 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EKX45239.1 - 1.2e-15 57.8 0.0 0.00031 20.7 0.0 5.2 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EKX45239.1 - 1.1e-07 32.2 0.3 0.022 15.0 0.0 4.7 4 0 0 4 4 3 1 AAA domain AAA PF00004.29 EKX45239.1 - 3.8e-06 27.4 0.6 1.3 9.5 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX45239.1 - 5.8e-06 26.8 0.0 0.87 10.0 0.0 4.4 4 1 0 4 4 3 2 AAA ATPase domain AAA_18 PF13238.6 EKX45239.1 - 6.9e-05 23.4 2.9 0.0047 17.5 0.0 4.8 5 0 0 5 5 2 1 AAA domain RNA_helicase PF00910.22 EKX45239.1 - 0.00011 22.6 0.2 2.2 8.7 0.0 3.9 3 0 0 3 3 3 1 RNA helicase PhoH PF02562.16 EKX45239.1 - 0.0053 16.2 1.8 1.8 8.0 0.0 3.7 3 0 0 3 3 3 1 PhoH-like protein AAA_24 PF13479.6 EKX45239.1 - 0.0098 15.6 1.5 4.5 6.9 0.0 4.1 3 1 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 EKX45239.1 - 0.011 15.1 0.4 6.6 6.1 0.0 3.6 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EKX45239.1 - 0.019 14.7 0.2 1.5 8.5 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_33 PF13671.6 EKX45239.1 - 0.021 15.0 0.3 38 4.4 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 EKX45239.1 - 0.022 14.5 2.2 5.7 6.6 0.3 3.2 3 0 0 3 3 3 0 AAA domain DEAD PF00270.29 EKX45239.1 - 0.022 14.5 0.1 6.3 6.5 0.1 2.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase ATPase PF06745.13 EKX45239.1 - 0.029 13.7 0.1 0.19 11.1 0.0 2.4 2 0 0 2 2 2 0 KaiC Rad17 PF03215.15 EKX45239.1 - 0.05 13.5 0.7 62 3.4 0.0 4.4 4 0 0 4 4 4 0 Rad17 P-loop domain T2SSE PF00437.20 EKX45239.1 - 0.081 12.0 2.2 6.1 5.8 0.0 3.9 5 0 0 5 5 5 0 Type II/IV secretion system protein DUF853 PF05872.12 EKX45239.1 - 0.2 10.2 1.8 13 4.2 0.1 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) AAA_19 PF13245.6 EKX45239.1 - 0.27 11.6 4.0 7.5 6.9 0.0 3.8 4 0 0 4 4 2 0 AAA domain TsaE PF02367.17 EKX45239.1 - 0.74 9.8 5.8 2 8.4 0.0 3.4 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 EKX45239.1 - 0.82 9.7 11.0 0.89 9.5 0.0 4.8 4 1 1 5 5 4 0 Type III restriction enzyme, res subunit FOP_dimer PF09398.10 EKX45240.1 - 1.4e-14 54.1 0.2 2.2e-14 53.4 0.2 1.3 1 0 0 1 1 1 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 EKX45240.1 - 1.7e-08 33.4 0.1 2.4e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 LisH Glyco_transf_15 PF01793.16 EKX45242.1 - 3.1e-33 115.4 11.0 5.6e-33 114.6 11.0 1.4 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase CW_binding_2 PF04122.12 EKX45243.1 - 0.13 12.9 0.1 0.33 11.6 0.1 1.6 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 BAG PF02179.16 EKX45244.1 - 3.3e-07 30.6 0.9 3.8e-07 30.5 0.9 1.1 1 0 0 1 1 1 1 BAG domain PDZ_6 PF17820.1 EKX45245.1 - 1.3e-05 24.9 0.2 3.6e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX45245.1 - 0.00038 20.7 0.1 0.00076 19.8 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX45245.1 - 0.0086 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Tricorn protease PDZ domain PDZ PF00595.24 EKX45245.1 - 0.13 12.6 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 PDZ domain DPM3 PF08285.11 EKX45246.1 - 0.0059 16.8 0.0 0.0059 16.8 0.0 2.4 3 1 0 3 3 3 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Bac_export_2 PF01312.19 EKX45246.1 - 5.9 6.0 5.4 30 3.7 5.1 2.2 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family HCO3_cotransp PF00955.21 EKX45247.1 - 5.5e-131 437.9 15.6 2.4e-70 237.8 2.7 2.0 1 1 1 2 2 2 2 HCO3- transporter family AAA PF00004.29 EKX45248.1 - 1.8e-39 135.2 0.1 8.7e-39 133.0 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EKX45248.1 - 1.3e-11 44.1 0.1 3.3e-11 42.8 0.1 1.7 1 1 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 EKX45248.1 - 1.6e-08 34.4 0.0 5.1e-08 32.8 0.0 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 EKX45248.1 - 6.3e-08 32.5 0.0 1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EKX45248.1 - 5.9e-05 23.1 0.4 0.00073 19.6 0.4 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EKX45248.1 - 0.0002 21.7 1.5 0.031 14.5 0.1 2.7 1 1 2 3 3 3 1 AAA domain TIP49 PF06068.13 EKX45248.1 - 0.0008 18.7 0.1 0.0014 17.9 0.1 1.4 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 EKX45248.1 - 0.0011 19.2 0.0 0.0016 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EKX45248.1 - 0.0033 17.8 2.0 0.064 13.6 2.0 2.8 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 EKX45248.1 - 0.012 15.1 0.3 0.028 13.8 0.3 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EKX45248.1 - 0.021 14.9 0.0 0.043 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EKX45248.1 - 0.028 14.2 0.0 0.071 12.8 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 EKX45248.1 - 0.049 13.4 0.2 0.1 12.3 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EKX45248.1 - 0.055 13.9 0.1 0.13 12.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EKX45248.1 - 0.058 12.8 0.3 2.9 7.2 0.0 2.7 2 1 1 3 3 3 0 Bacterial TniB protein AAA_7 PF12775.7 EKX45248.1 - 0.067 12.7 0.4 0.44 10.0 0.3 2.3 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 EKX45248.1 - 0.084 13.0 0.0 0.18 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain Toxin_trans PF07952.12 EKX45248.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain AAA_18 PF13238.6 EKX45248.1 - 0.16 12.5 0.3 0.38 11.3 0.1 1.8 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EKX45248.1 - 0.19 11.3 0.7 1.8 8.1 0.1 2.3 2 1 0 2 2 2 0 AAA domain fn3 PF00041.21 EKX45251.1 - 0.013 15.8 0.0 0.032 14.6 0.0 1.6 1 0 0 1 1 1 0 Fibronectin type III domain Proteasome PF00227.26 EKX45253.1 - 3.7e-63 212.5 0.1 4.5e-63 212.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EKX45253.1 - 2.8e-14 52.5 0.2 4.8e-14 51.7 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Aminotran_1_2 PF00155.21 EKX45254.1 - 2.6e-35 122.3 0.0 1.3e-34 119.9 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II CRM1_repeat_2 PF18784.1 EKX45254.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 Alliinase_C PF04864.13 EKX45254.1 - 0.11 11.3 0.0 0.37 9.6 0.0 1.8 2 0 0 2 2 2 0 Allinase DAP_epimerase PF01678.19 EKX45255.1 - 6.2e-46 155.5 0.5 1.9e-23 82.9 0.3 2.1 2 0 0 2 2 2 2 Diaminopimelate epimerase Orn_Arg_deC_N PF02784.16 EKX45256.1 - 9.7e-29 100.5 0.0 1.3e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EKX45256.1 - 1.6e-16 60.3 0.0 2.1e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain BAH PF01426.18 EKX45258.1 - 1.9e-15 56.8 0.0 8.4e-15 54.7 0.0 2.0 2 0 0 2 2 2 1 BAH domain LAMTOR PF15454.6 EKX45259.1 - 0.15 12.7 0.4 0.27 11.9 0.4 1.4 1 0 0 1 1 1 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator GLE1 PF07817.13 EKX45260.1 - 0.15 11.3 2.5 6.3 5.9 2.3 2.9 2 1 0 2 2 2 0 GLE1-like protein Citrate_ly_lig PF08218.11 EKX45260.1 - 0.52 10.0 5.8 2.7 7.6 1.1 2.7 1 1 2 3 3 3 0 Citrate lyase ligase C-terminal domain DUF1758 PF05585.12 EKX45260.1 - 0.64 9.8 10.0 2.1 8.1 9.1 2.2 1 1 1 2 2 2 0 Putative peptidase (DUF1758) RRM_1 PF00076.22 EKX45261.1 - 2.1e-18 65.9 0.0 3.4e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EKX45261.1 - 0.016 15.1 0.0 0.023 14.6 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif Limkain-b1 PF11608.8 EKX45261.1 - 0.083 13.0 0.1 0.16 12.1 0.1 1.5 1 1 0 1 1 1 0 Limkain b1 Nup35_RRM_2 PF14605.6 EKX45261.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EKX45261.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif DUF5427 PF10310.9 EKX45263.1 - 0.0055 15.7 15.7 0.0073 15.3 15.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5427) CENP-N PF05238.13 EKX45263.1 - 0.0073 15.7 8.6 0.0089 15.4 8.6 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like TFIIA PF03153.13 EKX45263.1 - 0.012 15.6 35.3 0.015 15.3 35.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TCP PF03634.13 EKX45263.1 - 0.013 16.0 16.3 0.02 15.4 16.3 1.3 1 0 0 1 1 1 0 TCP family transcription factor DDHD PF02862.17 EKX45263.1 - 0.014 15.5 5.7 0.022 14.9 5.7 1.4 1 0 0 1 1 1 0 DDHD domain Pkinase_fungal PF17667.1 EKX45263.1 - 0.057 12.2 8.6 0.066 12.0 8.6 1.1 1 0 0 1 1 1 0 Fungal protein kinase UPF0560 PF10577.9 EKX45263.1 - 0.081 11.4 15.0 0.099 11.1 15.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 G6B PF15096.6 EKX45263.1 - 0.094 12.5 1.5 0.12 12.2 1.5 1.2 1 0 0 1 1 1 0 G6B family SLC12 PF03522.15 EKX45263.1 - 0.099 11.7 11.1 0.11 11.5 11.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 EKX45263.1 - 0.1 10.8 14.2 0.13 10.6 14.2 1.1 1 0 0 1 1 1 0 CDC45-like protein CCDC53 PF10152.9 EKX45263.1 - 0.14 12.5 14.9 0.22 11.9 14.9 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Presenilin PF01080.17 EKX45263.1 - 0.15 10.8 18.7 0.18 10.5 18.7 1.1 1 0 0 1 1 1 0 Presenilin DUF2828 PF11443.8 EKX45263.1 - 0.15 10.1 15.3 0.19 9.8 15.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF4192 PF13830.6 EKX45263.1 - 0.2 11.7 6.7 0.23 11.5 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) CobT PF06213.12 EKX45263.1 - 0.22 10.9 18.9 0.3 10.4 18.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pex14_N PF04695.13 EKX45263.1 - 0.22 12.1 24.8 0.36 11.5 24.8 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RR_TM4-6 PF06459.12 EKX45263.1 - 0.34 10.7 17.7 0.44 10.3 17.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIP PF07454.11 EKX45263.1 - 0.38 10.2 12.9 0.48 9.8 12.9 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) LAP1C PF05609.12 EKX45263.1 - 0.49 9.4 14.5 0.56 9.2 14.5 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Nop53 PF07767.11 EKX45263.1 - 0.5 9.7 25.8 0.62 9.4 25.8 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF913 PF06025.12 EKX45263.1 - 0.51 9.3 7.1 0.61 9.0 7.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PAT1 PF09770.9 EKX45263.1 - 0.6 8.3 28.4 0.74 8.0 28.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Connexin PF00029.19 EKX45263.1 - 0.79 9.4 8.6 1.2 8.9 8.6 1.4 1 0 0 1 1 1 0 Connexin PepSY_TM PF03929.16 EKX45263.1 - 1.2 8.8 6.7 1.7 8.3 6.7 1.3 1 0 0 1 1 1 0 PepSY-associated TM region BORG_CEP PF14957.6 EKX45263.1 - 1.3 10.2 9.5 1.9 9.7 9.5 1.3 1 0 0 1 1 1 0 Cdc42 effector Neur_chan_memb PF02932.16 EKX45263.1 - 1.6 8.8 11.5 2 8.4 11.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EOS1 PF12326.8 EKX45263.1 - 2 8.3 6.4 3 7.8 6.4 1.4 1 0 0 1 1 1 0 N-glycosylation protein SprA-related PF12118.8 EKX45263.1 - 2 7.4 30.6 2.6 7.1 30.6 1.1 1 0 0 1 1 1 0 SprA-related family Hid1 PF12722.7 EKX45263.1 - 2.4 6.2 13.6 2.8 6.0 13.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SID-1_RNA_chan PF13965.6 EKX45263.1 - 2.6 6.4 3.1 2.7 6.3 3.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4366 PF14283.6 EKX45263.1 - 3.5 7.7 8.6 9.5 6.3 8.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Zip PF02535.22 EKX45263.1 - 3.6 6.7 5.0 4.5 6.4 5.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3408 PF11888.8 EKX45263.1 - 4.2 7.5 19.1 7.7 6.7 19.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) GREB1 PF15782.5 EKX45263.1 - 4.5 4.3 15.7 5 4.1 15.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Otopetrin PF03189.13 EKX45263.1 - 4.8 5.9 6.2 6 5.6 6.2 1.1 1 0 0 1 1 1 0 Otopetrin Vma12 PF11712.8 EKX45263.1 - 4.9 7.2 5.9 6.7 6.8 5.9 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase ALMT PF11744.8 EKX45263.1 - 5.3 5.8 12.3 6.7 5.4 12.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2370 PF10176.9 EKX45263.1 - 5.9 6.5 6.7 9 5.9 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) MDM10 PF12519.8 EKX45263.1 - 6.6 5.5 13.9 8.4 5.1 13.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Membralin PF09746.9 EKX45263.1 - 9.1 5.2 7.8 11 4.9 7.8 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF4407 PF14362.6 EKX45263.1 - 9.9 5.4 20.9 12 5.2 20.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3367 PF11847.8 EKX45265.1 - 0.086 10.7 0.0 0.092 10.6 0.0 1.1 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase CEL_III_C PF18054.1 EKX45265.1 - 0.13 12.3 0.5 0.16 12.0 0.5 1.2 1 0 0 1 1 1 0 CEL-III C-terminal YEATS PF03366.16 EKX45266.1 - 6.8e-30 102.9 0.1 1.4e-29 101.9 0.1 1.5 1 0 0 1 1 1 1 YEATS family UDPG_MGDP_dh_N PF03721.14 EKX45267.1 - 4.6e-28 98.1 0.0 5.5e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 EKX45267.1 - 2.3e-05 24.6 0.0 6.3e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.22 EKX45267.1 - 0.00023 22.0 0.0 0.00037 21.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 EKX45267.1 - 0.027 14.9 0.0 0.044 14.2 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EKX45267.1 - 0.066 12.6 0.0 0.1 12.0 0.0 1.4 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EKX45267.1 - 0.066 13.1 0.0 0.091 12.6 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EKX45267.1 - 0.089 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 EKX45267.1 - 0.14 12.8 0.0 0.22 12.1 0.0 1.5 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.9 EKX45267.1 - 0.17 11.8 0.0 0.81 9.6 0.0 1.9 2 0 0 2 2 2 0 Rossmann-like domain DUF412 PF04217.13 EKX45267.1 - 0.2 11.5 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF412 UDPG_MGDP_dh PF00984.19 EKX45268.1 - 2.4e-12 46.9 0.0 2.2e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 EKX45268.1 - 1.1e-06 29.0 0.0 1.9e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain SDA1 PF05285.12 EKX45268.1 - 1.4e-06 28.0 30.6 1.4e-06 28.0 30.6 1.3 2 0 0 2 2 2 1 SDA1 Mpp10 PF04006.12 EKX45268.1 - 6.8e-06 24.8 25.2 1.1e-05 24.1 25.2 1.3 1 0 0 1 1 1 1 Mpp10 protein G-7-MTase PF12803.7 EKX45268.1 - 0.16 11.1 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) SpoIIIAH PF12685.7 EKX45268.1 - 0.41 10.5 6.5 0.59 9.9 6.5 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein eIF-3c_N PF05470.12 EKX45268.1 - 0.91 7.8 17.6 13 3.9 17.6 2.0 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Nop14 PF04147.12 EKX45268.1 - 5.8 5.0 49.3 8.3 4.5 49.3 1.1 1 0 0 1 1 1 0 Nop14-like family Peptidase_M14 PF00246.24 EKX45269.1 - 1.2e-13 51.5 0.0 4.1e-13 49.8 0.0 1.8 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 EKX45269.1 - 1.4e-12 47.9 0.0 2.1e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 EKX45269.1 - 1.5e-07 30.8 0.0 2.1e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family ABC_tran PF00005.27 EKX45270.1 - 4.4e-31 108.2 0.2 6.8e-31 107.6 0.2 1.3 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 EKX45270.1 - 3.7e-07 30.5 0.3 0.0026 18.0 0.1 2.6 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 EKX45270.1 - 9.9e-06 25.0 0.0 2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin RsgA_GTPase PF03193.16 EKX45270.1 - 7.8e-05 22.6 0.1 0.00022 21.1 0.1 1.8 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 EKX45270.1 - 0.00053 19.9 0.1 0.0075 16.1 0.0 2.3 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 EKX45270.1 - 0.00064 19.9 0.7 0.0011 19.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.6 EKX45270.1 - 0.0012 18.4 0.3 0.0021 17.6 0.3 1.7 1 1 0 1 1 1 1 AAA domain VirE PF05272.11 EKX45270.1 - 0.0013 18.5 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 Virulence-associated protein E AAA_14 PF13173.6 EKX45270.1 - 0.0018 18.3 0.0 0.0044 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EKX45270.1 - 0.0036 17.7 0.7 0.0083 16.5 0.1 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 EKX45270.1 - 0.0047 17.2 0.1 0.009 16.3 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 EKX45270.1 - 0.0047 16.7 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EKX45270.1 - 0.0053 16.5 1.3 0.014 15.1 1.3 1.7 1 1 0 1 1 1 1 P-loop containing region of AAA domain cobW PF02492.19 EKX45270.1 - 0.0056 16.3 0.1 0.012 15.2 0.1 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.25 EKX45270.1 - 0.0057 16.3 0.2 0.0099 15.6 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain T2SSE PF00437.20 EKX45270.1 - 0.006 15.7 0.1 0.01 14.9 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein PduV-EutP PF10662.9 EKX45270.1 - 0.0072 16.1 0.3 0.04 13.7 0.1 2.0 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 EKX45270.1 - 0.0083 16.0 0.4 0.017 15.0 0.4 1.5 1 0 0 1 1 1 1 NACHT domain SRPRB PF09439.10 EKX45270.1 - 0.015 14.7 1.2 5.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit SRP54 PF00448.22 EKX45270.1 - 0.024 14.2 0.2 0.041 13.5 0.2 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 EKX45270.1 - 0.04 13.7 0.0 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain RecA PF00154.21 EKX45270.1 - 0.049 13.1 0.1 0.074 12.5 0.1 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_18 PF13238.6 EKX45270.1 - 0.051 14.1 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 EKX45270.1 - 0.06 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.6 EKX45270.1 - 0.062 13.6 0.0 0.19 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EKX45270.1 - 0.081 12.9 0.4 6.7 6.7 0.1 2.6 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EKX45270.1 - 0.086 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EKX45270.1 - 0.087 13.2 0.0 4.4 7.8 0.0 2.3 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 EKX45270.1 - 0.1 11.8 0.5 0.19 10.9 0.5 1.3 1 0 0 1 1 1 0 NB-ARC domain APS_kinase PF01583.20 EKX45270.1 - 0.11 12.4 0.2 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_23 PF13476.6 EKX45270.1 - 0.12 12.8 0.8 0.4 11.1 0.3 1.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EKX45270.1 - 0.17 12.0 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Rad17 PF03215.15 EKX45270.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Pox_A32 PF04665.12 EKX45270.1 - 0.23 10.9 0.1 0.4 10.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Cpn60_TCP1 PF00118.24 EKX45271.1 - 1.6e-152 508.6 8.0 1.8e-152 508.4 8.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1132 PF06575.12 EKX45271.1 - 0.097 13.1 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) Metallophos PF00149.28 EKX45272.1 - 5.1e-33 115.3 0.3 7e-33 114.9 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_6 PF13405.6 EKX45273.1 - 0.0015 18.3 0.0 0.0038 17.0 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 EKX45273.1 - 0.0034 16.8 0.0 0.0062 16.0 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EKX45273.1 - 0.023 15.2 0.0 0.027 14.9 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair Cpn60_TCP1 PF00118.24 EKX45274.1 - 6.7e-31 107.5 0.0 8.8e-31 107.1 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1132 PF06575.12 EKX45274.1 - 0.098 13.0 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) FYVE PF01363.21 EKX45277.1 - 6.3e-13 48.7 5.4 1.1e-12 47.8 5.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-B_box PF00643.24 EKX45277.1 - 1.1 9.5 5.9 0.34 11.1 1.9 2.1 2 0 0 2 2 2 0 B-box zinc finger Nudix_N_2 PF14803.6 EKX45277.1 - 1.8 8.6 8.9 0.71 9.8 0.4 3.2 1 1 2 3 3 3 0 Nudix N-terminal Cpn60_TCP1 PF00118.24 EKX45278.1 - 1.8e-16 59.9 0.0 5.6e-16 58.2 0.0 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family PDZ_6 PF17820.1 EKX45279.1 - 8.4e-11 41.5 0.2 2.2e-10 40.2 0.2 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX45279.1 - 1.4e-07 31.7 0.0 3.8e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX45279.1 - 0.03 14.3 0.0 0.14 12.1 0.0 2.1 1 1 0 1 1 1 0 Tricorn protease PDZ domain DUF3016 PF11454.8 EKX45279.1 - 0.034 13.9 2.2 0.085 12.6 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) Mei5 PF10376.9 EKX45279.1 - 0.96 9.3 20.6 1.9 8.3 12.3 2.4 2 0 0 2 2 2 0 Double-strand recombination repair protein PerC PF06069.11 EKX45279.1 - 9.5 6.6 9.1 1.6 9.0 0.1 2.9 3 0 0 3 3 3 0 PerC transcriptional activator RINT1_TIP1 PF04437.13 EKX45280.1 - 8.2e-47 160.2 0.0 2e-46 159.0 0.0 1.7 1 1 0 1 1 1 1 RINT-1 / TIP-1 family HBM PF16591.5 EKX45280.1 - 0.081 12.3 3.8 0.043 13.3 0.6 2.0 2 0 0 2 2 2 0 Helical bimodular sensor domain fn3 PF00041.21 EKX45281.1 - 2.9e-71 235.8 0.1 5.2e-11 42.7 0.0 8.5 8 0 0 8 8 8 7 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 EKX45281.1 - 1.8e-13 50.8 0.0 0.12 13.0 0.0 7.7 6 1 1 7 7 7 3 Purple acid Phosphatase, N-terminal domain SusE PF14292.6 EKX45281.1 - 5.2e-10 39.5 0.0 0.27 11.5 0.0 6.0 6 0 0 6 6 6 3 SusE outer membrane protein GPI-anchored PF10342.9 EKX45281.1 - 0.005 17.6 0.1 14 6.5 0.0 5.4 6 0 0 6 6 6 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Mfa_like_1 PF13149.6 EKX45281.1 - 0.019 15.0 0.1 0.31 11.0 0.0 2.7 3 0 0 3 3 3 0 Fimbrillin-like Tissue_fac PF01108.17 EKX45281.1 - 0.084 12.7 0.0 16 5.4 0.0 3.9 4 0 0 4 4 4 0 Tissue factor hnRNP_Q_AcD PF18360.1 EKX45281.1 - 0.1 12.5 0.0 2.3 8.2 0.0 2.8 2 0 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain Peptidase_M13_N PF05649.13 EKX45282.1 - 2.6e-71 241.3 6.4 3.3e-71 241.0 6.4 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 EKX45282.1 - 7.5e-59 198.8 0.0 2.4e-58 197.1 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M13 LysM PF01476.20 EKX45283.1 - 3.2e-10 39.9 0.0 5.7e-05 23.1 0.0 3.3 3 0 0 3 3 3 2 LysM domain PAE PF03283.13 EKX45283.1 - 2.1e-05 23.9 0.2 0.0026 16.9 0.0 2.1 2 0 0 2 2 2 2 Pectinacetylesterase Tox-GHH PF15636.6 EKX45283.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Myb_DNA-binding PF00249.31 EKX45284.1 - 2.2e-11 43.7 0.1 6.1e-11 42.3 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX45284.1 - 2.3e-11 43.8 0.1 7e-11 42.2 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain SLY PF12485.8 EKX45284.1 - 0.0012 19.6 4.2 0.0012 19.6 4.2 3.7 3 2 1 4 4 4 1 Lymphocyte signaling adaptor protein RTC PF01137.21 EKX45286.1 - 4.8e-53 179.6 0.0 5.5e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 EKX45286.1 - 4.7e-36 123.4 0.1 1e-35 122.3 0.1 1.6 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain NFACT-R_1 PF05670.13 EKX45287.1 - 0.00085 20.0 0.0 0.0012 19.4 0.0 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain SoxD PF04267.12 EKX45287.1 - 0.097 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Sarcosine oxidase, delta subunit family WD40 PF00400.32 EKX45288.1 - 1.1e-21 76.7 16.4 0.0001 23.0 0.2 7.1 7 1 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX45288.1 - 0.0011 19.2 0.1 0.55 10.6 0.1 3.9 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.21 EKX45288.1 - 0.059 12.1 0.0 0.092 11.5 0.0 1.2 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PAS_9 PF13426.7 EKX45289.1 - 5.2e-17 62.0 0.0 6.6e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EKX45289.1 - 2.5e-06 27.4 0.0 3.1e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.12 EKX45289.1 - 1.9e-05 24.9 0.0 2.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EKX45289.1 - 0.0082 16.1 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 EKX45289.1 - 0.1 12.8 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 PAS fold Vac14_Fig4_bd PF11916.8 EKX45290.1 - 1.2e-25 90.3 4.4 2.7e-25 89.0 4.4 1.6 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Telomere_reg-2 PF10193.9 EKX45290.1 - 0.017 15.5 0.4 0.13 12.7 0.0 2.6 2 0 0 2 2 2 0 Telomere length regulation protein Utp12 PF04003.12 EKX45290.1 - 0.045 14.1 0.2 1.7 9.0 0.1 2.7 2 0 0 2 2 2 0 Dip2/Utp12 Family CENP-B_dimeris PF09026.10 EKX45290.1 - 6.2 7.3 8.4 13 6.2 8.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ins_P5_2-kin PF06090.12 EKX45291.1 - 5.4e-69 233.1 0.0 6.2e-69 233.0 0.0 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase LysM PF01476.20 EKX45292.1 - 5.3e-13 48.8 0.5 1.6e-07 31.3 0.0 2.9 3 0 0 3 3 3 2 LysM domain PAE PF03283.13 EKX45292.1 - 0.0025 17.0 0.4 0.23 10.5 0.0 2.3 2 0 0 2 2 2 2 Pectinacetylesterase U-box PF04564.15 EKX45293.1 - 2.2e-15 56.6 0.1 2.4e-15 56.5 0.1 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX45293.1 - 2.1e-08 33.9 0.2 3.1e-08 33.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EKX45293.1 - 2.7e-06 27.3 0.0 3.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EKX45293.1 - 0.00019 21.2 0.0 0.00027 20.7 0.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX45293.1 - 0.087 13.2 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 EKX45293.1 - 0.088 13.1 0.1 0.14 12.5 0.1 1.4 1 1 0 1 1 1 0 RING-H2 zinc finger domain Rtf2 PF04641.12 EKX45293.1 - 0.092 12.1 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Pkinase PF00069.25 EKX45294.1 - 1.1e-23 83.9 0.0 2.2e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX45294.1 - 3.6e-21 75.6 0.0 7.1e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Antimicrobial_7 PF08102.11 EKX45294.1 - 0.0077 16.4 0.5 1.6 9.0 0.0 2.6 2 0 0 2 2 2 2 Scorpion antimicrobial peptide Kinase-like PF14531.6 EKX45294.1 - 0.063 12.6 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like NAGLU PF05089.12 EKX45295.1 - 9.6e-136 452.1 2.5 1.4e-135 451.6 2.5 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 EKX45295.1 - 4.6e-72 242.8 0.1 6.3e-72 242.3 0.1 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 EKX45295.1 - 4.6e-06 26.3 0.1 9e-06 25.4 0.1 1.5 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain CDP-OH_P_transf PF01066.21 EKX45296.1 - 7.7e-18 65.0 0.5 1.3e-17 64.3 0.5 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase fn2 PF00040.19 EKX45300.1 - 9.6e-10 38.6 59.6 0.059 13.7 2.1 10.9 9 5 0 9 9 9 7 Fibronectin type II domain SHOCT PF09851.9 EKX45300.1 - 0.023 14.4 0.0 0.023 14.4 0.0 2.0 2 0 0 2 2 2 0 Short C-terminal domain HCV_NS5a PF01506.19 EKX45300.1 - 0.25 11.3 1.4 0.83 9.6 0.4 2.4 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a protein membrane anchor Caldesmon PF02029.15 EKX45301.1 - 0.02 13.7 49.7 0.037 12.8 49.7 1.4 1 0 0 1 1 1 0 Caldesmon SDA1 PF05285.12 EKX45301.1 - 1.1 8.6 76.5 1.9 7.8 76.5 1.3 1 0 0 1 1 1 0 SDA1 Glyco_hydro_47 PF01532.20 EKX45303.1 - 5.1e-114 381.7 0.0 6.2e-114 381.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Sedlin_N PF04628.13 EKX45303.1 - 0.014 15.5 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region DUF1090 PF06476.12 EKX45305.1 - 0.00039 20.5 22.8 0.15 12.2 4.4 5.2 1 1 3 4 4 4 3 Protein of unknown function (DUF1090) HTH_37 PF13744.6 EKX45305.1 - 0.00069 19.5 12.1 0.68 9.9 0.5 3.7 2 1 1 3 3 3 3 Helix-turn-helix domain DUF4398 PF14346.6 EKX45305.1 - 0.00076 20.1 74.9 1.3 9.7 23.1 5.9 2 1 4 6 6 6 4 Domain of unknown function (DUF4398) DUF438 PF04282.13 EKX45305.1 - 0.0065 16.4 12.5 45 4.1 0.1 7.2 1 1 7 8 8 8 0 Family of unknown function (DUF438) Glyco_tran_WecB PF03808.13 EKX45305.1 - 0.013 15.5 5.1 0.48 10.4 0.7 2.6 1 1 2 3 3 3 0 Glycosyl transferase WecB/TagA/CpsF family FAM92 PF06730.11 EKX45305.1 - 0.38 10.1 6.0 0.49 9.8 0.7 2.4 2 1 0 2 2 2 0 FAM92 protein Rubi_NSP_C PF12601.8 EKX45305.1 - 8.3 6.6 12.7 45 4.2 0.2 4.7 3 1 3 6 6 6 0 Rubivirus non-structural protein Ribosomal_L6 PF00347.23 EKX45307.1 - 0.049 14.3 0.1 0.083 13.6 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L6 TrpP PF17099.5 EKX45309.1 - 0.03 14.1 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Tryptophan transporter TrpP Ephrin_rec_like PF07699.13 EKX45310.1 - 2.1e-18 65.8 79.6 3.8e-07 29.7 2.5 7.5 6 1 1 7 7 7 6 Putative ephrin-receptor like EGF_3 PF12947.7 EKX45310.1 - 0.0083 16.3 6.2 0.0083 16.3 6.2 8.5 8 1 1 9 9 9 3 EGF domain Cyt-b5 PF00173.28 EKX45312.1 - 1.1e-11 44.7 0.0 1.5e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain p450 PF00067.22 EKX45313.1 - 2.4e-21 76.0 0.0 3e-21 75.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Gag_p12 PF01141.18 EKX45314.1 - 0.022 15.1 0.1 0.025 14.9 0.1 1.1 1 0 0 1 1 1 0 Gag polyprotein, inner coat protein p12 DUF3969 PF13108.6 EKX45315.1 - 0.15 12.0 0.0 0.42 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3969) Ank PF00023.30 EKX45317.1 - 6.8e-10 38.9 0.8 0.00022 21.5 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EKX45317.1 - 3.7e-09 36.1 0.2 0.011 16.2 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EKX45317.1 - 3.2e-08 34.1 0.3 0.00043 20.8 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX45317.1 - 6.3e-06 26.4 1.8 0.011 16.1 0.3 3.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX45317.1 - 0.00016 22.2 0.6 0.00054 20.5 0.3 2.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Yippee-Mis18 PF03226.14 EKX45318.1 - 0.00048 20.3 0.0 0.00086 19.5 0.0 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly AAA_12 PF13087.6 EKX45319.1 - 2.2e-33 115.6 3.9 1.1e-26 93.8 0.5 2.7 2 1 1 3 3 3 2 AAA domain AAA_11 PF13086.6 EKX45319.1 - 3.8e-06 26.9 0.3 8.1e-06 25.8 0.3 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EKX45319.1 - 0.00012 21.9 0.1 0.00026 20.7 0.1 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EKX45319.1 - 0.0018 18.1 0.1 0.0049 16.6 0.0 1.8 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF2034 PF10356.9 EKX45319.1 - 0.081 12.3 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2034) MapZ_C2 PF18708.1 EKX45320.1 - 0.06 13.6 0.0 0.09 13.1 0.0 1.4 1 0 0 1 1 1 0 MapZ extracellular C-terminal domain 2 Keratin_2_head PF16208.5 EKX45321.1 - 0.019 15.1 0.4 0.024 14.8 0.4 1.2 1 0 0 1 1 1 0 Keratin type II head Methyltransf_32 PF13679.6 EKX45322.1 - 0.0015 18.5 0.1 0.0025 17.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain GTP_EFTU PF00009.27 EKX45323.1 - 3.9e-30 104.8 0.0 1.5e-28 99.7 0.0 3.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EKX45323.1 - 1.8e-16 60.0 0.0 5.2e-16 58.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 EKX45323.1 - 2.5e-08 33.9 0.0 7.5e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MRP-L47 PF06984.13 EKX45324.1 - 1.7e-22 79.3 0.0 3.6e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 EKX45324.1 - 3.3e-11 43.0 1.1 1.2e-09 38.0 0.3 2.3 2 0 0 2 2 2 1 Ribosomal L29 protein SOCS PF12610.8 EKX45324.1 - 0.061 13.7 0.0 0.28 11.6 0.0 2.1 2 0 0 2 2 2 0 Suppressor of cytokine signalling LRR_6 PF13516.6 EKX45326.1 - 1.8e-12 46.2 7.2 2.4e-05 24.0 0.4 4.4 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 EKX45326.1 - 0.002 18.5 3.3 0.025 15.0 1.4 2.5 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX45326.1 - 0.027 15.0 0.9 2.2 9.2 0.1 3.1 3 0 0 3 3 3 0 Leucine Rich Repeat Glyco_transf_25 PF01755.17 EKX45328.1 - 4.6e-08 33.2 0.0 0.0018 18.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) PH PF00169.29 EKX45329.1 - 7.5e-10 39.3 0.4 1.3e-09 38.4 0.4 1.5 1 0 0 1 1 1 1 PH domain PH_3 PF14593.6 EKX45329.1 - 1e-06 28.8 0.1 1.8e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EKX45329.1 - 0.00044 20.6 4.6 0.0054 17.1 4.6 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 EKX45329.1 - 0.032 14.5 1.2 0.23 11.7 1.2 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain Cation_efflux PF01545.21 EKX45330.1 - 4e-30 105.0 2.2 4.8e-30 104.8 2.2 1.1 1 0 0 1 1 1 1 Cation efflux family RseC_MucC PF04246.12 EKX45330.1 - 0.048 13.6 0.1 0.29 11.1 0.0 2.1 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Cation_efflux PF01545.21 EKX45331.1 - 4e-30 105.0 2.2 4.8e-30 104.8 2.2 1.1 1 0 0 1 1 1 1 Cation efflux family RseC_MucC PF04246.12 EKX45331.1 - 0.048 13.6 0.1 0.29 11.1 0.0 2.1 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Hus1 PF04005.12 EKX45332.1 - 2.7e-30 105.5 0.1 3.1e-30 105.3 0.1 1.0 1 0 0 1 1 1 1 Hus1-like protein PCNA_N PF00705.18 EKX45332.1 - 0.033 13.9 0.1 0.046 13.4 0.1 1.3 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain Aminotran_5 PF00266.19 EKX45333.1 - 3.3e-41 141.5 0.0 4.6e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EKX45333.1 - 2.9e-05 23.6 0.0 7.8e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_3 PF00202.21 EKX45333.1 - 0.082 11.5 0.0 0.39 9.3 0.0 2.1 1 1 0 1 1 1 0 Aminotransferase class-III Mg_trans_NIPA PF05653.14 EKX45334.1 - 4e-19 68.8 6.7 4.4e-19 68.7 6.7 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EKX45334.1 - 0.00081 19.6 9.9 0.00081 19.6 9.9 1.4 1 1 0 1 1 1 1 EamA-like transporter family Phage_GP20 PF06810.11 EKX45336.1 - 0.011 15.5 0.8 0.018 14.8 0.8 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF3829 PF12889.7 EKX45336.1 - 0.017 14.6 0.0 0.25 10.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) BLOC1_2 PF10046.9 EKX45336.1 - 0.02 15.2 0.8 0.05 13.9 0.3 1.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 EKX45336.1 - 0.026 14.6 0.4 0.046 13.8 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2203 PF09969.9 EKX45336.1 - 0.033 14.9 1.4 0.063 14.0 0.3 1.9 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Rx_N PF18052.1 EKX45336.1 - 0.047 14.0 1.1 0.069 13.4 0.2 1.7 2 0 0 2 2 2 0 Rx N-terminal domain DUF4298 PF14131.6 EKX45336.1 - 0.055 13.4 0.6 0.055 13.4 0.6 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) DUF4615 PF15393.6 EKX45336.1 - 0.07 13.7 0.3 0.12 12.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) WXG100 PF06013.12 EKX45336.1 - 0.11 12.7 0.2 0.39 11.0 0.2 1.9 1 1 0 1 1 1 0 Proteins of 100 residues with WXG CK_II_beta PF01214.18 EKX45339.1 - 0.048 13.5 0.7 0.09 12.6 0.7 1.3 1 0 0 1 1 1 0 Casein kinase II regulatory subunit Troponin PF00992.20 EKX45340.1 - 0.11 12.8 1.2 2.1 8.6 0.1 2.0 1 1 1 2 2 2 0 Troponin Pkinase PF00069.25 EKX45341.1 - 4.7e-11 42.5 0.0 5.1e-11 42.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX45341.1 - 0.015 14.6 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Rubredoxin_2 PF18073.1 EKX45342.1 - 0.17 11.6 0.1 0.17 11.6 0.1 4.6 4 1 0 4 4 4 0 Rubredoxin metal binding domain PSP PF04046.16 EKX45343.1 - 1.4e-10 40.9 1.7 2.5e-10 40.1 1.7 1.4 1 0 0 1 1 1 1 PSP Glyco_transf_11 PF01531.16 EKX45344.1 - 2e-11 43.7 0.1 7.4e-10 38.5 0.1 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 11 PLAT PF01477.23 EKX45344.1 - 0.036 14.6 0.1 1.1 9.8 0.0 2.6 2 0 0 2 2 2 0 PLAT/LH2 domain Lipoprotein_22 PF17294.2 EKX45345.1 - 9.4e-05 22.1 0.2 0.00013 21.6 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised lipoprotein family TPPII_N PF12583.8 EKX45345.1 - 0.0098 16.5 0.6 0.021 15.4 0.6 1.5 1 0 0 1 1 1 1 Tripeptidyl peptidase II N terminal SET PF00856.28 EKX45346.1 - 1.1e-13 51.9 0.4 1.7e-12 48.1 0.4 2.1 1 1 0 1 1 1 1 SET domain AWS PF17907.1 EKX45346.1 - 2.4e-07 30.7 6.3 2.4e-07 30.7 6.3 2.1 2 0 0 2 2 2 1 AWS domain ubiquitin PF00240.23 EKX45347.1 - 4.5e-16 58.4 0.7 5.3e-16 58.1 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EKX45347.1 - 2.5e-07 30.4 0.5 3.2e-07 30.1 0.4 1.3 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like FYRC PF05965.14 EKX45347.1 - 0.045 13.9 0.0 0.059 13.5 0.0 1.1 1 0 0 1 1 1 0 F/Y rich C-terminus Ubiquitin_4 PF18036.1 EKX45347.1 - 0.046 13.8 0.7 0.1 12.7 0.7 1.6 1 1 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_2 PF14560.6 EKX45347.1 - 0.046 14.2 2.4 0.26 11.8 2.4 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain FOXP-CC PF16159.5 EKX45348.1 - 0.073 13.7 0.4 0.18 12.5 0.4 1.6 1 0 0 1 1 1 0 FOXP coiled-coil domain DUF3390 PF11870.8 EKX45349.1 - 0.084 13.2 0.1 0.22 11.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) LcnG-beta PF11632.8 EKX45350.1 - 0.14 12.1 0.3 0.33 10.9 0.0 1.7 2 0 0 2 2 2 0 Lactococcin G-beta Pkinase PF00069.25 EKX45351.1 - 5.5e-47 160.4 0.0 1.2e-46 159.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX45351.1 - 5.2e-24 84.9 0.0 9.7e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX45351.1 - 0.0031 16.9 0.0 0.0048 16.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX45351.1 - 0.041 13.8 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4007 PF13182.6 EKX45352.1 - 0.00077 18.7 0.7 0.00092 18.4 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4007) TPR_12 PF13424.6 EKX45353.1 - 1.8e-08 34.5 1.8 0.1 12.9 0.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX45353.1 - 1.1e-07 31.4 0.4 0.03 14.4 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX45353.1 - 2.1e-07 30.4 1.2 0.0026 17.5 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX45353.1 - 3.7e-05 23.6 0.7 0.29 11.5 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX45353.1 - 0.00096 19.0 1.6 0.38 10.9 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat IQ PF00612.27 EKX45353.1 - 0.0013 18.3 3.2 0.18 11.7 0.5 3.3 2 0 0 2 2 2 2 IQ calmodulin-binding motif MCM_bind PF09739.9 EKX45354.1 - 2.1e-97 327.0 13.5 4.4e-42 144.3 1.5 3.0 2 1 1 3 3 3 3 Mini-chromosome maintenance replisome factor IMS_C PF11799.8 EKX45354.1 - 0.0094 16.6 1.7 0.55 10.9 0.5 2.9 1 1 1 3 3 3 1 impB/mucB/samB family C-terminal domain MCM_lid PF17855.1 EKX45354.1 - 0.048 14.1 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 MCM AAA-lid domain tRNA_anti-codon PF01336.25 EKX45354.1 - 0.096 12.7 0.0 0.32 11.0 0.0 1.9 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Collagen PF01391.18 EKX45355.1 - 8.1e-19 67.1 71.9 5.2e-08 32.5 36.2 3.0 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Z1 PF10593.9 EKX45355.1 - 0.18 11.3 0.1 0.25 10.8 0.1 1.1 1 0 0 1 1 1 0 Z1 domain MORN PF02493.20 EKX45357.1 - 2.9e-47 155.8 55.1 7.5e-08 31.8 1.7 10.7 11 0 0 11 11 11 8 MORN repeat DUF3048_C PF17479.2 EKX45357.1 - 0.042 14.2 16.6 9.1 6.7 2.2 5.3 2 1 3 5 5 5 0 Protein of unknown function (DUF3048) C-terminal domain PRP38_assoc PF12871.7 EKX45357.1 - 0.61 10.7 12.7 0.064 13.9 7.1 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Chitin_bind_4 PF00379.23 EKX45357.1 - 3.2 8.3 9.4 1.1 9.8 1.3 3.2 2 0 0 2 2 2 0 Insect cuticle protein Glyco_transf_49 PF13896.6 EKX45359.1 - 2.9e-22 79.5 0.0 1.9e-20 73.5 0.0 2.2 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan SPX PF03105.19 EKX45359.1 - 7.5 6.4 7.2 13 5.5 0.3 2.2 2 0 0 2 2 2 0 SPX domain HTH_IclR PF09339.10 EKX45360.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain Alpha_kinase PF02816.18 EKX45361.1 - 1.8e-48 165.1 0.1 2.1e-48 164.9 0.1 1.0 1 0 0 1 1 1 1 Alpha-kinase family CPSF100_C PF13299.6 EKX45363.1 - 0.005 17.0 3.0 0.005 17.0 3.0 2.4 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal NPR3 PF03666.13 EKX45363.1 - 0.01 14.7 0.0 0.01 14.7 0.0 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 V_ATPase_I PF01496.19 EKX45363.1 - 6 4.7 10.5 10 3.9 10.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pkinase PF00069.25 EKX45364.1 - 8.8e-39 133.4 0.0 1.2e-38 133.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX45364.1 - 3.1e-20 72.6 0.0 4e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX45364.1 - 0.0098 15.2 0.1 0.028 13.7 0.1 1.6 1 1 0 1 1 1 1 Kinase-like DUF4586 PF15239.6 EKX45365.1 - 5.1e-28 99.1 22.3 1.1e-15 58.7 6.1 4.9 2 2 2 4 4 4 4 Domain of unknown function (DUF4586) Cep57_CLD PF14073.6 EKX45366.1 - 0.021 14.9 0.1 0.027 14.5 0.1 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 PP2C PF00481.21 EKX45368.1 - 2.2e-07 30.8 0.0 0.008 15.8 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 EKX45368.1 - 0.0002 21.4 0.0 0.00035 20.5 0.0 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 EKX45368.1 - 0.016 14.9 0.1 0.031 13.9 0.1 1.5 1 1 0 1 1 1 0 Protein phosphatase 2C DUF4807 PF16065.5 EKX45368.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4807) Endonuclease_1 PF04231.13 EKX45370.1 - 2e-16 60.4 0.0 4.3e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Endonuclease I Big_8 PF17961.1 EKX45370.1 - 5.5e-05 23.3 2.1 2.6 8.2 0.0 8.9 11 0 0 11 11 11 1 Bacterial Ig domain WD40 PF00400.32 EKX45371.1 - 7.7e-66 216.4 36.5 1.5e-07 32.0 0.1 14.5 14 1 0 14 14 14 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX45371.1 - 1.4e-19 70.2 3.5 0.00047 20.4 0.0 8.7 5 4 4 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EKX45371.1 - 1.2e-08 34.1 7.4 0.0011 17.7 0.0 5.3 4 2 1 5 5 5 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EKX45371.1 - 1.4e-06 27.5 2.8 0.47 9.4 0.0 5.4 4 1 3 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EKX45371.1 - 1.9e-05 24.2 0.3 1.5 8.0 0.0 4.6 2 1 2 4 4 4 2 WD40-like domain Syncollin PF15138.6 EKX45371.1 - 0.068 13.4 0.0 0.36 11.0 0.0 2.2 2 0 0 2 2 2 0 Syncollin ComC PF03047.14 EKX45371.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 COMC family Glyco_transf_41 PF13844.6 EKX45372.1 - 5.7e-72 242.7 0.0 1.1e-35 123.0 0.0 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_11 PF13414.6 EKX45372.1 - 1.6e-10 40.5 0.3 1.6e-05 24.5 0.0 3.3 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 EKX45372.1 - 1.9e-09 37.0 0.0 0.044 14.0 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX45372.1 - 4.2e-09 35.8 0.9 0.0019 18.2 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX45372.1 - 6.4e-09 35.3 2.2 0.0012 18.5 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX45372.1 - 1.1e-08 35.2 4.4 0.00019 21.6 0.6 4.9 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX45372.1 - 1.8e-07 31.1 0.3 0.077 13.4 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX45372.1 - 9.5e-06 25.3 12.0 0.02 14.7 0.1 4.8 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX45372.1 - 0.00013 22.5 0.9 1.4 9.9 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX45372.1 - 0.0038 17.8 0.0 0.073 13.7 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 EKX45372.1 - 0.016 15.8 0.4 9.4 7.2 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX45372.1 - 0.018 15.5 0.4 0.87 10.1 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EKX45372.1 - 0.031 14.3 4.9 13 6.0 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX45372.1 - 0.34 11.7 3.2 86 4.1 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat PDZ_6 PF17820.1 EKX45373.1 - 2e-06 27.5 0.1 0.00035 20.4 0.0 2.5 1 1 1 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX45373.1 - 9.1e-05 22.7 0.0 0.022 15.1 0.0 2.3 1 1 1 2 2 2 2 PDZ domain Pkinase PF00069.25 EKX45374.1 - 1.4e-51 175.4 0.0 4.2e-35 121.4 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EKX45374.1 - 4.7e-27 94.9 0.0 6.9e-23 81.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 EKX45374.1 - 0.00082 18.8 0.1 0.0031 16.9 0.0 1.8 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L13 PF00572.18 EKX45376.1 - 8.2e-41 139.2 0.0 9.8e-41 138.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 OpuAC PF04069.12 EKX45377.1 - 0.042 13.4 0.3 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 Substrate binding domain of ABC-type glycine betaine transport system Ephrin_rec_like PF07699.13 EKX45377.1 - 0.58 10.0 11.6 3.1 7.6 3.3 3.2 1 1 2 3 3 3 0 Putative ephrin-receptor like Ndc1_Nup PF09531.10 EKX45378.1 - 1.3 7.6 12.0 1.3 7.6 12.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TGBp3 PF02495.17 EKX45378.1 - 1.5 8.6 7.9 3.5 7.4 7.9 1.7 1 0 0 1 1 1 0 Triple gene block 3 DUF4131 PF13567.6 EKX45378.1 - 2.9 7.5 10.7 3.8 7.1 10.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) MOEP19 PF16005.5 EKX45379.1 - 0.18 11.8 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 KH-like RNA-binding domain S6PP PF05116.13 EKX45381.1 - 4.2e-33 114.9 0.0 5.8e-22 78.4 0.0 2.7 2 1 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 EKX45381.1 - 3.1e-14 53.3 0.0 9e-10 38.7 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EKX45381.1 - 0.0049 17.3 0.0 4.4 7.7 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EKX45381.1 - 0.056 13.7 0.1 1.5 9.0 0.0 2.2 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Zn_Tnp_IS1595 PF12760.7 EKX45382.1 - 0.029 14.3 0.7 0.076 13.0 0.7 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain SOUL PF04832.12 EKX45384.1 - 2.7e-10 40.7 0.0 7.6e-10 39.2 0.0 1.7 2 0 0 2 2 2 1 SOUL heme-binding protein dCMP_cyt_deam_1 PF00383.23 EKX45385.1 - 1.8e-11 43.8 0.2 3.3e-11 43.0 0.2 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EKX45385.1 - 2.8e-07 30.4 0.6 0.00087 19.0 0.0 2.3 2 0 0 2 2 2 2 MafB19-like deaminase APOBEC3 PF18771.1 EKX45385.1 - 0.025 14.7 0.1 0.19 11.8 0.0 2.2 2 0 0 2 2 2 0 APOBEC3 Bd3614-deam PF14439.6 EKX45385.1 - 0.027 14.6 2.3 0.03 14.4 0.4 2.0 2 1 0 2 2 2 0 Bd3614-like deaminase Hamartin PF04388.12 EKX45386.1 - 0.54 8.9 11.9 0.62 8.7 11.9 1.1 1 0 0 1 1 1 0 Hamartin protein Bcr-Abl_Oligo PF09036.10 EKX45386.1 - 0.82 9.7 4.3 1.1 9.3 2.5 2.1 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain HSP70 PF00012.20 EKX45386.1 - 4 5.5 17.6 6.5 4.8 17.6 1.3 1 0 0 1 1 1 0 Hsp70 protein APG6_N PF17675.1 EKX45386.1 - 4.3 7.9 24.5 7.7 7.0 24.5 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DSPn PF14671.6 EKX45387.1 - 1.8e-22 80.3 0.0 2.1e-21 76.9 0.0 2.3 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EKX45387.1 - 8.8e-16 57.9 0.0 1.6e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX45387.1 - 1.7e-05 24.5 0.0 2.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX45387.1 - 5.1e-05 23.4 0.0 0.0001 22.5 0.0 1.4 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EKX45387.1 - 0.0046 17.0 0.0 0.0063 16.5 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Bac_rhodopsin PF01036.18 EKX45388.1 - 4.7e-26 91.8 14.0 5.8e-26 91.4 14.0 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DPM2 PF07297.12 EKX45388.1 - 0.053 13.8 1.4 0.053 13.8 1.4 2.6 2 1 0 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) UNC-93 PF05978.16 EKX45389.1 - 3.3e-14 52.9 5.9 3.3e-14 52.9 5.9 2.9 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 EKX45389.1 - 1.9 7.4 32.8 8 5.3 23.4 3.2 1 1 1 2 2 2 0 Major Facilitator Superfamily Ank_2 PF12796.7 EKX45390.1 - 4.1e-10 40.1 0.0 7.3e-05 23.3 0.0 1.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX45390.1 - 8.1e-05 22.8 0.0 0.00027 21.1 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX45390.1 - 9.7e-05 22.6 0.0 0.00022 21.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 EKX45390.1 - 0.0004 20.9 0.0 0.086 13.4 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX45390.1 - 0.00067 19.9 0.0 0.0029 18.0 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 EKX45391.1 - 3.7e-10 40.3 0.0 7e-05 23.3 0.0 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX45391.1 - 4.3e-05 23.7 0.0 0.0001 22.5 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX45391.1 - 0.00017 21.9 0.0 0.00039 20.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 EKX45391.1 - 0.00043 20.5 0.1 0.0021 18.4 0.0 2.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EKX45391.1 - 0.0011 19.5 0.0 0.14 12.7 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) GlcNAc PF11397.8 EKX45392.1 - 3.4e-68 230.7 0.1 1.4e-56 192.5 0.0 2.2 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) 2OG-FeII_Oxy_3 PF13640.6 EKX45392.1 - 4.9e-18 65.8 0.0 8.6e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 EKX45392.1 - 4e-14 53.0 0.0 6.9e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PRKCSH_1 PF13015.6 EKX45393.1 - 0.089 12.5 0.2 0.29 10.8 0.1 1.8 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein Thioredoxin PF00085.20 EKX45394.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Hexapep PF00132.24 EKX45395.1 - 4.5e-14 51.5 2.5 6.9e-05 22.4 0.1 4.5 4 1 0 5 5 5 3 Bacterial transferase hexapeptide (six repeats) zf-RING_2 PF13639.6 EKX45398.1 - 3.9e-12 46.3 12.2 8.2e-12 45.3 12.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EKX45398.1 - 3.3e-09 36.3 6.6 7.2e-09 35.2 6.6 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EKX45398.1 - 7.4e-07 29.4 13.0 1.9e-06 28.0 13.0 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EKX45398.1 - 1.5e-06 27.9 11.3 2.6e-06 27.2 11.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX45398.1 - 6.3e-06 26.0 11.2 1.1e-05 25.2 11.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX45398.1 - 0.00016 21.6 5.1 0.00029 20.8 5.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EKX45398.1 - 0.002 18.2 9.4 0.0077 16.3 9.4 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EKX45398.1 - 0.0049 16.7 10.8 0.0081 16.0 10.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX45398.1 - 0.011 15.7 9.5 0.02 14.9 9.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 EKX45398.1 - 0.33 10.9 12.1 0.71 9.8 12.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 EKX45398.1 - 3.9 7.7 11.8 14 6.0 11.8 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 EKX45398.1 - 7.6 6.2 13.9 13 5.5 12.3 2.0 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type LRR_6 PF13516.6 EKX45399.1 - 2e-09 36.8 16.0 0.00099 19.0 0.0 7.1 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.7 EKX45399.1 - 0.0041 17.5 0.2 0.012 16.0 0.2 1.8 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX45399.1 - 0.0046 16.7 0.6 0.033 13.9 0.7 2.1 1 1 0 1 1 1 1 Leucine rich repeat ubiquitin PF00240.23 EKX45400.1 - 1.6e-21 75.8 0.0 1.4e-11 44.0 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 EKX45400.1 - 1.2e-09 37.9 0.0 0.0014 18.4 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like CPBP PF02517.16 EKX45401.1 - 2.1e-13 50.5 1.4 2.1e-13 50.5 1.4 2.8 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease SLD5_C PF16922.5 EKX45402.1 - 3.6e-11 43.1 0.3 8.4e-11 41.9 0.3 1.7 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 EKX45402.1 - 0.043 14.3 1.4 0.089 13.3 1.2 1.6 1 1 0 1 1 1 0 GINS complex protein Phe_ZIP PF08916.11 EKX45402.1 - 0.091 13.5 1.5 0.17 12.6 1.5 1.5 1 0 0 1 1 1 0 Phenylalanine zipper Glyco_transf_49 PF13896.6 EKX45404.1 - 8.2e-24 84.6 0.0 8.8e-19 68.0 0.0 2.2 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan DUF2237 PF09996.9 EKX45405.1 - 4.7e-55 184.5 0.1 5.3e-55 184.3 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) Pro_isomerase PF00160.21 EKX45406.1 - 3.2e-43 147.8 0.1 4.1e-43 147.4 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Flavokinase PF01687.17 EKX45407.1 - 9.1e-31 106.4 0.0 1.1e-30 106.2 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase Chloroa_b-bind PF00504.21 EKX45408.1 - 2e-35 122.7 0.1 2.6e-35 122.4 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Pet191_N PF10203.9 EKX45409.1 - 5.7e-21 74.6 6.9 6.3e-21 74.4 6.9 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.13 EKX45409.1 - 0.049 13.8 3.9 0.055 13.6 1.6 2.0 2 0 0 2 2 2 0 CHCH domain CX9C PF16860.5 EKX45409.1 - 0.12 12.4 5.7 1.7 8.7 0.2 2.4 2 1 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, E1-E2_ATPase PF00122.20 EKX45411.1 - 3e-22 79.0 0.1 1e-20 74.0 0.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EKX45411.1 - 1.4e-15 58.2 0.0 1e-07 32.5 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EKX45411.1 - 0.00015 21.8 0.0 0.00034 20.6 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EKX45411.1 - 0.063 13.0 0.0 4.4 6.9 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 EKX45411.1 - 0.093 13.1 0.0 0.45 10.9 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase ABC_tran PF00005.27 EKX45412.1 - 5.6e-27 94.9 0.0 1.1e-26 93.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EKX45412.1 - 1.6e-05 24.8 0.5 0.0012 18.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EKX45412.1 - 0.0015 18.5 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 EKX45412.1 - 0.0047 16.4 0.1 0.026 14.0 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EKX45412.1 - 0.015 15.6 0.2 0.19 12.0 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 EKX45412.1 - 0.033 14.6 0.0 0.057 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EKX45412.1 - 0.084 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain KDGP_aldolase PF07071.11 EKX45412.1 - 0.21 11.4 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 KDGP aldolase RCC1 PF00415.18 EKX45413.1 - 2.3e-36 124.2 14.5 3.2e-11 43.7 0.0 4.1 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX45413.1 - 5.9e-20 70.6 13.4 6.6e-06 25.8 1.3 4.2 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat PH PF00169.29 EKX45414.1 - 0.0035 17.8 0.4 0.0035 17.8 0.4 2.5 3 0 0 3 3 3 1 PH domain PH_11 PF15413.6 EKX45414.1 - 5.6 7.5 15.1 0.03 14.7 2.0 3.3 2 1 0 2 2 2 0 Pleckstrin homology domain DSPn PF14671.6 EKX45415.1 - 0.052 14.0 0.0 0.095 13.1 0.0 1.5 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half Rv2175c_C PF18367.1 EKX45415.1 - 0.16 12.1 0.0 0.7 10.0 0.0 2.0 2 0 0 2 2 2 0 Rv2175c C-terminal domain of unknown function MerR_2 PF13591.6 EKX45416.1 - 0.031 14.1 4.0 0.1 12.4 4.0 1.9 1 0 0 1 1 1 0 MerR HTH family regulatory protein GAF PF01590.26 EKX45416.1 - 0.17 12.6 0.0 0.33 11.6 0.0 1.6 1 0 0 1 1 1 0 GAF domain NBP1 PF08537.10 EKX45416.1 - 0.28 10.6 7.4 0.88 8.9 4.8 2.3 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 GvpK PF05121.12 EKX45416.1 - 0.6 10.2 8.3 0.21 11.7 4.6 2.2 2 0 0 2 2 2 0 Gas vesicle protein K YabA PF06156.13 EKX45416.1 - 0.89 10.2 9.0 0.36 11.5 5.4 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Laminin_II PF06009.12 EKX45416.1 - 5.4 7.0 9.6 40 4.2 9.6 2.4 1 1 0 1 1 1 0 Laminin Domain II Nas2_N PF18265.1 EKX45417.1 - 7.4e-15 54.6 1.0 1.1e-13 50.8 1.0 2.0 1 1 0 1 1 1 1 Nas2 N_terminal domain DUF4140 PF13600.6 EKX45417.1 - 0.53 10.8 4.9 0.47 10.9 2.9 1.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) APG6_N PF17675.1 EKX45417.1 - 0.62 10.6 8.9 0.39 11.3 4.1 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region TMF_DNA_bd PF12329.8 EKX45417.1 - 0.72 9.9 8.7 3.6 7.7 3.1 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Troponin PF00992.20 EKX45417.1 - 0.91 9.8 8.4 7.9 6.8 8.4 2.0 1 1 0 1 1 1 0 Troponin Actin PF00022.19 EKX45418.1 - 2e-65 221.0 0.0 3.3e-33 114.9 0.0 2.5 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 EKX45418.1 - 0.071 11.9 0.0 0.65 8.8 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein KH_1 PF00013.29 EKX45419.1 - 1e-30 105.3 2.6 1.4e-09 37.7 0.1 4.5 4 0 0 4 4 4 3 KH domain EF-hand_7 PF13499.6 EKX45419.1 - 2.4e-14 53.5 0.6 5.4e-09 36.4 0.6 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX45419.1 - 1.6e-13 49.2 3.8 0.002 17.5 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EKX45419.1 - 3e-09 36.1 4.0 0.065 13.2 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain RRM_1 PF00076.22 EKX45419.1 - 3.2e-09 36.5 0.0 8.6e-09 35.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_8 PF13833.6 EKX45419.1 - 8.2e-07 28.8 3.8 0.00014 21.6 0.2 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EKX45419.1 - 5.4e-06 25.7 3.1 0.0032 16.9 0.0 3.6 3 0 0 3 3 3 1 EF hand EF-hand_4 PF12763.7 EKX45419.1 - 0.00035 20.5 5.2 0.0063 16.5 0.0 3.3 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand RE_TaqI PF09573.10 EKX45419.1 - 0.071 12.9 0.4 0.13 12.1 0.4 1.3 1 0 0 1 1 1 0 TaqI restriction endonuclease KH_2 PF07650.17 EKX45419.1 - 2.7 7.9 9.3 2.4 8.0 0.4 3.3 2 1 1 3 3 3 0 KH domain Ank_2 PF12796.7 EKX45420.1 - 6.7e-12 45.8 0.0 9.7e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX45420.1 - 3.5e-10 39.9 0.0 1.1e-05 25.6 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EKX45420.1 - 9.9e-08 31.7 0.0 0.00087 19.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EKX45420.1 - 9.8e-07 29.2 0.1 0.022 15.3 0.0 2.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX45420.1 - 0.0015 18.8 0.0 0.79 10.1 0.0 2.4 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Carb_anhydrase PF00194.21 EKX45421.1 - 6.2e-25 88.2 0.3 1.1e-12 48.0 0.1 2.5 2 1 0 2 2 2 2 Eukaryotic-type carbonic anhydrase DUF126 PF01989.16 EKX45421.1 - 0.17 11.7 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 Aconitase X swivel domain PspB PF06667.12 EKX45422.1 - 0.001 19.0 19.6 0.44 10.6 1.6 5.4 4 0 0 4 4 4 3 Phage shock protein B Gln_amidase PF15644.6 EKX45422.1 - 0.0054 17.7 27.1 11 7.0 0.0 9.7 3 2 7 10 10 10 3 Papain fold toxin 1, glutamine deamidase HIP1_clath_bdg PF16515.5 EKX45422.1 - 0.62 10.7 189.5 0.042 14.4 8.7 14.8 6 5 9 15 15 15 0 Clathrin-binding domain of Huntingtin-interacting protein 1 pXO2-72 PF17443.2 EKX45423.1 - 0.15 12.3 0.6 0.88 9.9 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein pXO2-72 SAYSvFN PF10260.9 EKX45424.1 - 4.4e-22 77.8 0.3 6.1e-22 77.3 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) NEMP PF10225.9 EKX45424.1 - 0.069 12.8 0.0 0.071 12.8 0.0 1.1 1 0 0 1 1 1 0 NEMP family FA_desaturase PF00487.24 EKX45424.1 - 0.13 12.0 0.1 0.14 12.0 0.1 1.1 1 0 0 1 1 1 0 Fatty acid desaturase Methyltransf_32 PF13679.6 EKX45425.1 - 4.2e-11 43.1 0.0 6.9e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Wzy_C PF04932.15 EKX45425.1 - 0.026 14.2 0.1 0.055 13.1 0.1 1.5 1 0 0 1 1 1 0 O-Antigen ligase Methyltransf_31 PF13847.6 EKX45425.1 - 0.028 14.2 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EKX45425.1 - 0.038 14.7 0.2 0.14 12.8 0.1 2.0 2 0 0 2 2 2 0 Methyltransferase domain zf-H2C2_2 PF13465.6 EKX45426.1 - 1.2e-07 31.8 0.5 1.2e-07 31.8 0.5 3.4 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.26 EKX45426.1 - 1.3e-06 28.5 11.4 0.00066 20.0 0.2 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EKX45426.1 - 0.00083 20.0 13.6 0.022 15.5 0.2 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 EKX45426.1 - 0.0019 18.8 1.3 0.063 13.9 0.2 2.4 2 0 0 2 2 2 1 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 EKX45426.1 - 0.005 17.1 0.9 0.0094 16.2 0.9 1.5 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 EKX45426.1 - 0.0065 16.2 4.7 0.089 12.6 0.5 2.9 2 0 0 2 2 2 1 C2H2-type zinc-finger domain Fer4_20 PF14691.6 EKX45426.1 - 0.86 9.4 3.5 2.7 7.8 0.0 2.8 2 1 1 3 3 3 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster PDZ_6 PF17820.1 EKX45428.1 - 4.9e-06 26.3 0.2 1.3e-05 25.0 0.2 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX45428.1 - 4.7e-05 23.7 0.0 0.00014 22.1 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX45428.1 - 0.0043 17.3 0.2 0.015 15.6 0.0 1.9 2 0 0 2 2 2 1 PDZ domain Mito_carr PF00153.27 EKX45430.1 - 7.2e-35 118.8 0.4 6.6e-18 64.4 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein REJ PF02010.15 EKX45431.1 - 2.8e-52 178.0 6.8 2.8e-52 178.0 6.8 1.8 2 0 0 2 2 2 1 REJ domain Big_9 PF17963.1 EKX45431.1 - 1.8e-13 51.0 35.6 0.11 13.2 0.1 11.5 11 0 0 11 11 11 5 Bacterial Ig domain Cadherin_3 PF16184.5 EKX45431.1 - 1e-08 35.1 0.0 8.4 6.4 0.0 7.0 6 0 0 6 6 6 3 Cadherin-like DUF4215 PF13948.6 EKX45431.1 - 3.3e-06 27.4 5.1 1.6e-05 25.3 5.1 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4215) TIG_plexin PF17960.1 EKX45431.1 - 0.023 14.7 0.4 0.24 11.4 0.0 2.9 2 0 0 2 2 2 0 TIG domain FAD_binding_1 PF00667.20 EKX45432.1 - 3e-45 154.5 0.0 4.5e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EKX45432.1 - 1.3e-31 109.8 0.0 2.7e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EKX45432.1 - 1.1e-15 58.2 0.1 5.2e-15 56.0 0.1 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.7 EKX45432.1 - 0.0087 15.8 0.0 0.023 14.4 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_5 PF12724.7 EKX45432.1 - 0.044 14.0 0.0 0.56 10.4 0.0 2.2 2 0 0 2 2 2 0 Flavodoxin domain Hemerythrin PF01814.23 EKX45434.1 - 6.2e-12 46.3 1.9 2e-11 44.7 1.9 1.9 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain EzrA PF06160.12 EKX45434.1 - 0.12 10.5 1.7 0.19 9.8 1.7 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Beta_helix PF13229.6 EKX45435.1 - 2.8e-14 53.3 0.4 5.9e-11 42.5 0.3 2.4 2 0 0 2 2 2 2 Right handed beta helix region NosD PF05048.13 EKX45435.1 - 9.8e-06 25.0 0.0 3e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Periplasmic copper-binding protein (NosD) Aldedh PF00171.22 EKX45436.1 - 2.1e-196 652.9 0.1 4.2e-152 506.9 0.0 2.0 2 0 0 2 2 2 2 Aldehyde dehydrogenase family DUF1487 PF07368.11 EKX45436.1 - 1.5e-07 31.1 0.3 1.4e-06 28.0 0.3 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) LuxC PF05893.14 EKX45436.1 - 1.3e-06 27.7 0.7 0.011 14.8 0.0 2.2 2 0 0 2 2 2 2 Acyl-CoA reductase (LuxC) OmdA PF13376.6 EKX45436.1 - 0.49 10.4 2.9 3.3 7.8 0.3 2.4 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated TPR_16 PF13432.6 EKX45436.1 - 8.1 7.2 8.7 12 6.7 1.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TTL PF03133.15 EKX45437.1 - 1.3e-06 27.8 0.0 3.2e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family Sulf_transp PF04143.14 EKX45438.1 - 3.3e-38 132.0 23.7 3.3e-38 132.0 23.7 1.6 1 1 1 2 2 2 1 Sulphur transport DUF442 PF04273.13 EKX45439.1 - 2.1e-06 27.8 0.1 1.1e-05 25.4 0.1 1.8 1 1 0 1 1 1 1 Putative phosphatase (DUF442) Y_phosphatase2 PF03162.13 EKX45439.1 - 0.00028 20.5 0.0 0.0003 20.4 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EKX45439.1 - 0.0008 19.2 0.0 0.00088 19.1 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EKX45439.1 - 0.067 13.1 0.1 0.17 11.9 0.1 1.6 1 1 0 1 1 1 0 Tyrosine phosphatase family DUF442 PF04273.13 EKX45440.1 - 1.1e-11 44.8 0.0 1.2e-11 44.6 0.0 1.0 1 0 0 1 1 1 1 Putative phosphatase (DUF442) Y_phosphatase3 PF13350.6 EKX45440.1 - 0.00014 21.9 0.0 0.00076 19.5 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EKX45440.1 - 0.0042 17.2 0.0 0.0049 17.0 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 EKX45440.1 - 0.16 11.8 0.0 0.16 11.8 0.0 1.3 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Sulf_transp PF04143.14 EKX45441.1 - 1e-37 130.4 22.5 1.3e-37 130.1 22.5 1.0 1 0 0 1 1 1 1 Sulphur transport DeoC PF01791.9 EKX45442.1 - 2.7e-27 95.9 0.0 3.3e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase 4HFCP_synth PF04476.13 EKX45442.1 - 0.0062 16.3 0.0 0.0087 15.8 0.0 1.2 1 0 0 1 1 1 1 4-HFC-P synthase HA PF03457.14 EKX45442.1 - 0.14 12.5 0.1 0.38 11.1 0.0 1.8 2 0 0 2 2 2 0 Helicase associated domain APG17 PF04108.12 EKX45442.1 - 0.16 11.1 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 Yippee-Mis18 PF03226.14 EKX45443.1 - 4.2e-11 43.0 0.0 4.8e-11 42.8 0.0 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Gin PF10764.9 EKX45443.1 - 0.041 13.8 0.7 6.2 6.9 0.0 2.4 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin RIG-I_C-RD PF11648.8 EKX45443.1 - 0.11 12.7 0.2 0.25 11.6 0.2 1.5 1 1 0 1 1 1 0 C-terminal domain of RIG-I CSN7a_helixI PF18392.1 EKX45443.1 - 0.11 12.4 0.5 2.2 8.3 0.0 2.1 2 0 0 2 2 2 0 COP9 signalosome complex subunit 7a helix I domain PHD PF00628.29 EKX45444.1 - 1.1e-13 50.9 4.8 1.2e-13 50.8 4.8 1.0 1 0 0 1 1 1 1 PHD-finger zf-RING_2 PF13639.6 EKX45444.1 - 0.00091 19.5 7.1 0.001 19.3 7.1 1.1 1 0 0 1 1 1 1 Ring finger domain PHD_2 PF13831.6 EKX45444.1 - 0.0011 18.5 2.6 0.0011 18.5 2.6 2.1 2 1 0 2 2 2 1 PHD-finger zf-PHD-like PF15446.6 EKX45444.1 - 0.0018 17.9 0.9 0.0022 17.6 0.9 1.1 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain Zf_RING PF16744.5 EKX45444.1 - 0.0079 16.3 1.6 0.0079 16.3 1.6 1.7 1 1 1 2 2 2 1 KIAA1045 RING finger zf-RING_9 PF13901.6 EKX45444.1 - 0.0085 16.1 1.2 0.0093 16.0 1.2 1.1 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon Zn-ribbon_8 PF09723.10 EKX45444.1 - 0.0088 16.1 3.1 0.12 12.5 0.2 2.1 1 1 1 2 2 2 1 Zinc ribbon domain C1_2 PF03107.16 EKX45444.1 - 0.027 14.8 6.5 0.18 12.1 3.7 2.0 2 0 0 2 2 2 0 C1 domain Prok-RING_1 PF14446.6 EKX45444.1 - 0.046 13.7 8.7 0.15 12.0 5.2 2.6 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 PhnA_Zn_Ribbon PF08274.12 EKX45444.1 - 0.057 13.4 7.1 0.58 10.2 0.2 3.1 3 0 0 3 3 3 0 PhnA Zinc-Ribbon FYVE_2 PF02318.16 EKX45444.1 - 0.099 12.9 0.6 0.099 12.9 0.6 1.8 1 1 1 2 2 2 0 FYVE-type zinc finger zf-B_box PF00643.24 EKX45444.1 - 0.56 10.4 9.1 3.7 7.8 0.2 2.9 2 1 1 3 3 3 0 B-box zinc finger A2L_zn_ribbon PF08792.10 EKX45444.1 - 0.97 9.2 7.9 10 6.0 4.2 3.1 2 1 0 2 2 2 0 A2L zinc ribbon domain ADK_lid PF05191.14 EKX45444.1 - 4 7.5 9.0 5.2 7.1 0.1 3.0 3 0 0 3 3 3 0 Adenylate kinase, active site lid Rubredoxin_2 PF18073.1 EKX45444.1 - 5.7 6.8 12.4 3.1 7.6 1.3 3.1 3 0 0 3 3 3 0 Rubredoxin metal binding domain C1_1 PF00130.22 EKX45444.1 - 7.6 6.5 10.9 0.26 11.2 4.0 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) JmjC PF02373.22 EKX45445.1 - 1.2e-38 132.1 0.0 2.5e-38 131.0 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Hen1_L PF12623.7 EKX45447.1 - 0.17 10.9 0.0 0.36 9.8 0.0 1.5 2 0 0 2 2 2 0 RNA repair, ligase-Pnkp-associating, region of Hen1 PKD_channel PF08016.12 EKX45448.1 - 6.4e-24 84.4 25.2 3.9e-20 71.9 16.1 2.3 2 0 0 2 2 2 2 Polycystin cation channel C2 PF00168.30 EKX45448.1 - 1.8e-18 66.7 0.0 8.6e-18 64.5 0.0 2.2 1 0 0 1 1 1 1 C2 domain Ion_trans PF00520.31 EKX45448.1 - 7.8e-13 48.2 25.3 3.5e-12 46.1 25.3 1.9 1 1 0 1 1 1 1 Ion transport protein EF-hand_5 PF13202.6 EKX45448.1 - 0.0085 15.5 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 1 EF hand RLAN PF14401.6 EKX45448.1 - 0.033 13.8 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATPgrasp N-terminal domain Carn_acyltransf PF00755.20 EKX45449.1 - 1.6e-164 548.8 0.0 2.2e-100 337.0 0.0 2.1 1 1 1 2 2 2 2 Choline/Carnitine o-acyltransferase BST2 PF16716.5 EKX45450.1 - 0.17 12.5 8.0 0.046 14.3 2.7 2.5 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 PLC-beta_C PF08703.10 EKX45450.1 - 0.19 11.7 8.7 0.053 13.5 5.5 1.7 2 0 0 2 2 2 0 PLC-beta C terminal Proteasome PF00227.26 EKX45451.1 - 0.012 15.1 0.1 0.032 13.7 0.1 1.7 1 0 0 1 1 1 0 Proteasome subunit TMV_coat PF00721.21 EKX45451.1 - 1.3 8.8 7.2 0.23 11.3 0.4 3.0 3 2 0 3 3 3 0 Virus coat protein (TMV like) Ank_4 PF13637.6 EKX45453.1 - 4.5e-20 71.8 3.6 6.2e-10 39.4 0.3 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX45453.1 - 1.5e-16 60.2 1.4 1.9e-09 37.6 0.6 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX45453.1 - 2.8e-16 59.9 0.9 4e-07 30.5 0.3 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EKX45453.1 - 5.7e-14 51.8 1.4 2.6e-05 24.5 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EKX45453.1 - 6e-09 35.4 0.8 0.014 15.9 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat TilS PF09179.11 EKX45453.1 - 0.016 15.7 0.6 0.25 11.8 0.1 2.7 2 0 0 2 2 2 0 TilS substrate binding domain DUF3881 PF12997.7 EKX45453.1 - 0.068 12.4 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) Methyltransf_24 PF13578.6 EKX45454.1 - 0.042 14.9 0.1 0.21 12.6 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain CmcI PF04989.12 EKX45454.1 - 0.059 13.1 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase DUF4506 PF14958.6 EKX45454.1 - 0.16 11.5 0.0 0.82 9.2 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4506) PhyH PF05721.13 EKX45455.1 - 6.2e-07 29.9 0.0 7.7e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Ank_2 PF12796.7 EKX45456.1 - 6.9e-06 26.6 0.2 1.3e-05 25.7 0.2 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX45456.1 - 0.00014 22.1 0.0 0.00028 21.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX45456.1 - 0.00037 21.0 0.2 0.0015 19.1 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX45456.1 - 0.0026 18.1 0.5 0.44 11.3 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EKX45456.1 - 0.061 13.8 0.0 0.64 10.6 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat Endostatin PF06482.11 EKX45456.1 - 0.064 12.7 0.3 0.13 11.7 0.3 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin HTH_32 PF13565.6 EKX45456.1 - 0.07 13.7 1.1 0.21 12.2 1.1 1.8 1 0 0 1 1 1 0 Homeodomain-like domain DUF4375 PF14300.6 EKX45456.1 - 0.17 12.2 1.5 0.63 10.3 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4375) ALIX_LYPXL_bnd PF13949.6 EKX45456.1 - 4.2 6.6 12.5 0.58 9.4 7.1 2.0 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV His_Phos_2 PF00328.22 EKX45457.1 - 3.1e-19 69.6 0.1 1.3e-14 54.3 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) SurA_N_3 PF13624.6 EKX45457.1 - 0.04 13.7 0.1 0.092 12.5 0.1 1.6 1 0 0 1 1 1 0 SurA N-terminal domain Collagen PF01391.18 EKX45458.1 - 3.7e-08 33.0 35.8 8.5e-08 31.8 35.8 1.5 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Ion_trans PF00520.31 EKX45459.1 - 2.2e-31 109.0 27.9 3e-31 108.5 27.9 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EKX45459.1 - 3.7e-07 29.2 23.7 4.9e-07 28.8 15.6 2.1 1 1 1 2 2 2 2 Polycystin cation channel DUF1704 PF08014.11 EKX45459.1 - 0.015 14.3 0.1 0.04 13.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) PH_13 PF16652.5 EKX45459.1 - 0.03 14.1 0.1 0.08 12.8 0.1 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain PH PF00169.29 EKX45459.1 - 0.031 14.8 0.0 0.087 13.3 0.0 1.7 1 0 0 1 1 1 0 PH domain EF-hand_6 PF13405.6 EKX45459.1 - 0.13 12.3 0.1 0.61 10.2 0.1 2.2 1 0 0 1 1 1 0 EF-hand domain DUF4834 PF16118.5 EKX45459.1 - 8 7.5 8.5 0.62 11.1 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) LRR_4 PF12799.7 EKX45460.1 - 2.6e-08 34.0 5.5 7.8e-06 26.2 0.6 1.7 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX45460.1 - 4.9e-08 32.6 2.5 6.9e-08 32.1 2.5 1.2 1 0 0 1 1 1 1 Leucine rich repeat LRRNT_2 PF08263.12 EKX45460.1 - 0.0011 19.3 0.3 0.0021 18.3 0.3 1.6 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 EKX45460.1 - 0.004 17.5 1.1 0.17 12.5 0.2 3.0 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.6 EKX45460.1 - 0.035 14.2 0.2 0.63 10.2 0.1 2.4 2 0 0 2 2 2 0 Leucine Rich repeat Pkinase PF00069.25 EKX45461.1 - 2.1e-19 69.9 0.0 2.4e-19 69.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX45461.1 - 1.1e-17 64.2 0.0 1.4e-17 63.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX45461.1 - 0.037 13.4 0.2 0.23 10.7 0.2 1.9 1 1 0 1 1 1 0 Kinase-like MORN PF02493.20 EKX45462.1 - 7.5e-50 163.9 62.1 2.9e-07 30.0 0.8 10.9 10 1 0 10 10 10 10 MORN repeat MAP65_ASE1 PF03999.12 EKX45464.1 - 5.6e-05 22.0 6.7 5.6e-05 22.0 6.7 3.4 3 2 0 3 3 3 1 Microtubule associated protein (MAP65/ASE1 family) CART PF06373.11 EKX45464.1 - 0.9 9.8 4.1 3 8.1 0.7 3.0 2 0 0 2 2 2 0 Cocaine and amphetamine regulated transcript protein (CART) Orthopox_B11R PF07033.11 EKX45465.1 - 0.015 15.1 0.0 1.4 8.8 0.0 3.0 3 0 0 3 3 3 0 Orthopoxvirus B11R protein S-antigen PF05756.11 EKX45465.1 - 0.17 12.2 0.3 0.31 11.4 0.3 1.4 1 0 0 1 1 1 0 S-antigen protein MAP65_ASE1 PF03999.12 EKX45467.1 - 2.1e-12 46.6 6.3 2.1e-12 46.6 6.3 4.0 2 2 0 4 4 4 1 Microtubule associated protein (MAP65/ASE1 family) CART PF06373.11 EKX45467.1 - 1 9.6 3.9 3.9 7.7 0.7 3.1 2 0 0 2 2 2 0 Cocaine and amphetamine regulated transcript protein (CART) Ank_4 PF13637.6 EKX45469.1 - 1.8e-13 50.7 0.3 0.00017 22.1 0.0 3.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX45469.1 - 4.3e-13 49.6 0.3 9.1e-13 48.6 0.1 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX45469.1 - 9e-10 38.6 4.6 7.2e-05 23.0 0.3 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EKX45469.1 - 5.3e-07 29.5 1.2 0.066 13.8 0.0 4.8 5 1 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EKX45469.1 - 2.7e-05 24.4 1.2 0.0031 17.8 0.4 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) PH PF00169.29 EKX45471.1 - 7.7e-17 61.7 1.4 1.5e-16 60.8 1.4 1.4 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 EKX45471.1 - 0.00037 20.9 4.0 0.0021 18.5 4.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 EKX45471.1 - 0.0035 17.4 0.0 0.1 12.7 0.0 2.2 1 1 0 1 1 1 1 PH domain DUF3220 PF11516.8 EKX45471.1 - 0.054 13.7 0.1 0.12 12.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3120) Glyco_transf_41 PF13844.6 EKX45472.1 - 8e-63 212.5 0.0 2.7e-32 111.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_1 PF00515.28 EKX45472.1 - 7.3e-19 66.7 4.8 2.3e-05 24.0 0.1 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX45472.1 - 1.3e-16 59.2 5.8 0.00034 20.5 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX45472.1 - 1.9e-16 59.5 6.9 0.0007 19.2 0.0 5.1 1 1 4 5 5 5 4 TPR repeat TPR_8 PF13181.6 EKX45472.1 - 6.5e-14 50.9 0.5 0.0033 17.5 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX45472.1 - 1e-10 42.1 2.6 2.2e-05 25.0 0.4 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX45472.1 - 1.1e-10 41.9 3.2 7e-05 23.3 0.1 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX45472.1 - 2.5e-09 36.9 7.8 0.0057 17.0 0.0 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX45472.1 - 5.9e-08 32.2 0.1 0.0045 16.9 0.0 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX45472.1 - 1.2e-07 31.9 0.5 0.23 12.4 0.0 4.2 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX45472.1 - 5.5e-07 29.8 6.8 0.076 13.3 0.1 4.9 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX45472.1 - 0.0016 18.2 9.6 0.0085 15.9 0.2 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat NARP1 PF12569.8 EKX45472.1 - 0.0025 16.8 0.1 0.17 10.7 0.0 2.1 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 EKX45472.1 - 0.021 15.0 0.1 5.4 7.2 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 EKX45472.1 - 0.24 10.8 0.9 0.83 9.1 0.6 2.0 2 0 0 2 2 2 0 Est1 DNA/RNA binding domain TPR_6 PF13174.6 EKX45472.1 - 0.84 10.4 3.8 53 4.8 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat Arm PF00514.23 EKX45473.1 - 3.8e-05 23.6 9.5 0.00044 20.2 0.0 5.9 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EKX45473.1 - 0.019 15.3 17.4 0.39 11.1 0.6 5.7 5 3 2 7 7 7 0 HEAT repeats RICTOR_V PF14668.6 EKX45473.1 - 0.025 14.8 0.3 0.37 11.0 0.1 2.9 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 HEAT PF02985.22 EKX45473.1 - 0.13 12.6 4.5 9.2 6.8 0.1 5.3 5 0 0 5 5 5 0 HEAT repeat DUF3361 PF11841.8 EKX45473.1 - 0.2 11.6 3.6 0.22 11.5 0.1 2.8 2 1 2 4 4 4 0 Domain of unknown function (DUF3361) Oxidored_molyb PF00174.19 EKX45474.1 - 6.6e-47 159.3 0.0 1.5e-46 158.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EKX45474.1 - 4.9e-34 117.3 0.7 1e-33 116.3 0.7 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 EKX45474.1 - 1.8e-12 47.2 0.0 3.3e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BNR PF02012.20 EKX45474.1 - 0.088 12.9 0.2 0.41 10.8 0.2 2.3 1 0 0 1 1 1 0 BNR/Asp-box repeat Big_7 PF17957.1 EKX45474.1 - 0.11 13.3 0.2 1 10.2 0.2 2.6 1 1 0 1 1 1 0 Bacterial Ig domain HEAT_2 PF13646.6 EKX45475.1 - 1e-19 70.7 15.0 2.1e-09 37.6 1.4 3.9 2 1 3 5 5 5 3 HEAT repeats HEAT PF02985.22 EKX45475.1 - 1.7e-14 52.7 6.7 0.026 14.8 0.0 5.5 5 0 0 5 5 5 4 HEAT repeat HEAT_EZ PF13513.6 EKX45475.1 - 0.00067 20.1 0.3 0.63 10.6 0.0 3.0 2 0 0 2 2 2 2 HEAT-like repeat Cnd1 PF12717.7 EKX45475.1 - 0.012 15.7 0.2 17 5.4 0.0 3.2 1 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 ERAP1_C PF11838.8 EKX45475.1 - 0.015 14.8 0.5 0.03 13.9 0.5 1.4 1 0 0 1 1 1 0 ERAP1-like C-terminal domain Stc1 PF12898.7 EKX45475.1 - 0.059 13.9 0.5 0.059 13.9 0.5 2.9 3 0 0 3 3 3 0 Stc1 domain Arm PF00514.23 EKX45475.1 - 0.13 12.3 0.3 11 6.2 0.0 3.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.7 EKX45475.1 - 1.6 9.1 3.7 48 4.4 0.0 3.5 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion DNA_RNApol_7kD PF03604.13 EKX45475.1 - 1.8 8.3 5.1 0.58 9.9 0.5 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Patched PF02460.18 EKX45476.1 - 2.9e-30 105.1 34.1 7.1e-19 67.4 11.5 3.2 3 0 0 3 3 3 2 Patched family Sterol-sensing PF12349.8 EKX45476.1 - 3.5e-18 65.9 26.1 5.4e-13 49.0 8.1 2.7 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 EKX45476.1 - 2.8e-06 26.5 26.4 0.00013 21.1 11.5 2.4 2 0 0 2 2 2 2 MMPL family Histone_HNS PF00816.21 EKX45477.1 - 0.031 15.1 2.9 0.042 14.7 0.1 2.6 2 0 0 2 2 2 0 H-NS histone family DUF3450 PF11932.8 EKX45477.1 - 0.053 12.8 1.7 0.13 11.6 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FtsL PF04999.13 EKX45477.1 - 0.088 12.8 0.5 0.3 11.1 0.5 1.8 1 0 0 1 1 1 0 Cell division protein FtsL Thioredoxin_11 PF18078.1 EKX45477.1 - 0.14 12.2 0.1 0.3 11.2 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like SNTX domain RNase_HII PF01351.18 EKX45478.1 - 3.4e-48 164.1 0.0 4.7e-48 163.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII LRR_6 PF13516.6 EKX45479.1 - 9.4e-06 25.3 6.8 0.0024 17.8 0.2 4.3 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 EKX45479.1 - 0.0043 17.4 1.5 3.1 8.3 0.0 3.6 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) EF-hand_6 PF13405.6 EKX45479.1 - 0.011 15.6 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 EKX45479.1 - 0.019 14.5 0.0 0.041 13.4 0.0 1.6 1 0 0 1 1 1 0 EF hand DUF507 PF04368.13 EKX45479.1 - 0.17 11.8 0.0 0.5 10.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF507) Slx4 PF09494.10 EKX45479.1 - 0.17 11.8 0.0 2.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Slx4 endonuclease WW PF00397.26 EKX45480.1 - 6.8e-17 61.3 9.8 2.9e-08 33.7 1.2 2.3 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 EKX45480.1 - 0.01 16.1 2.7 1.5 9.1 0.2 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain TIP49_C PF17856.1 EKX45481.1 - 0.015 15.4 2.5 3.9 7.7 0.2 3.9 4 0 0 4 4 4 0 TIP49 AAA-lid domain DUF948 PF06103.11 EKX45481.1 - 8.6 6.7 20.4 3 8.1 0.0 7.8 7 1 1 8 8 8 0 Bacterial protein of unknown function (DUF948) PA14 PF07691.12 EKX45482.1 - 9.4e-10 38.5 0.3 1.3e-07 31.5 0.0 3.6 4 0 0 4 4 4 1 PA14 domain Fe_hyd_SSU PF02256.17 EKX45482.1 - 0.023 14.8 0.1 3.6 7.7 0.0 2.5 2 0 0 2 2 2 0 Iron hydrogenase small subunit Toprim_4 PF13662.6 EKX45482.1 - 0.15 12.6 0.1 0.37 11.3 0.1 1.7 1 0 0 1 1 1 0 Toprim domain Exo_endo_phos PF03372.23 EKX45483.1 - 2.4e-15 56.7 0.0 4.1e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EKX45483.1 - 0.0047 16.8 0.5 0.63 9.9 0.0 3.0 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase Peripla_BP_1 PF00532.21 EKX45483.1 - 0.048 13.1 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family WW PF00397.26 EKX45484.1 - 8.7e-08 32.1 3.1 2.1e-07 30.9 3.1 1.7 1 0 0 1 1 1 1 WW domain FANCL_C PF11793.8 EKX45484.1 - 0.12 12.6 0.6 1.8 8.8 0.1 2.2 2 0 0 2 2 2 0 FANCL C-terminal domain DUF2076 PF09849.9 EKX45484.1 - 7.6 6.5 19.9 2.3e+02 1.6 19.9 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Ank_2 PF12796.7 EKX45485.1 - 6.9e-15 55.4 0.4 3.8e-09 37.0 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX45485.1 - 3.9e-13 49.4 1.2 7.6e-09 35.7 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX45485.1 - 3.1e-11 43.6 0.0 3e-06 27.7 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX45485.1 - 3.8e-08 33.4 1.2 0.00026 21.3 0.0 3.4 4 1 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EKX45485.1 - 1e-06 28.6 0.0 0.00017 21.8 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat SNF2_N PF00176.23 EKX45486.1 - 9.9e-29 100.1 0.0 1.6e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX45486.1 - 1.3e-10 41.6 0.0 4.1e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX45486.1 - 9.9e-06 25.7 0.0 4.3e-05 23.6 0.0 2.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EKX45486.1 - 0.0086 16.4 0.0 0.03 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain Flavi_DEAD PF07652.14 EKX45486.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain U-box PF04564.15 EKX45487.1 - 5.7e-14 52.0 0.1 6.1e-14 51.9 0.1 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX45487.1 - 3.9e-06 26.6 0.0 4.8e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 EKX45487.1 - 0.00045 20.3 0.0 0.0005 20.1 0.0 1.1 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_2 PF13923.6 EKX45487.1 - 0.00065 19.5 0.0 0.00082 19.2 0.0 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX45487.1 - 0.0019 18.2 0.0 0.0025 17.8 0.0 1.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EKX45487.1 - 0.01 16.1 0.0 0.014 15.7 0.0 1.3 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EKX45487.1 - 0.11 12.7 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Ank_2 PF12796.7 EKX45488.1 - 2.7e-21 75.9 0.3 3.6e-13 49.9 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX45488.1 - 5.4e-14 52.1 0.4 1.1e-09 38.3 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX45488.1 - 7.9e-14 51.8 0.1 3.3e-08 33.9 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX45488.1 - 3.9e-13 49.2 0.0 4.1e-05 23.8 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EKX45488.1 - 6e-13 47.7 0.1 7.6e-05 22.8 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Zn_clus PF00172.18 EKX45489.1 - 1.1e-06 28.7 6.6 2.3e-06 27.6 6.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.29 EKX45491.1 - 1.5e-43 148.6 0.0 7.9e-43 146.2 0.0 2.2 4 0 0 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX45491.1 - 2.3e-25 89.1 0.0 7.2e-25 87.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.14 EKX45491.1 - 0.09 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain Ank_4 PF13637.6 EKX45492.1 - 5.8e-22 77.8 0.1 7.7e-12 45.5 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX45492.1 - 1.3e-19 68.2 0.0 2.1e-06 27.6 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EKX45492.1 - 6.4e-18 65.1 0.0 2.1e-09 37.8 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EKX45492.1 - 4.9e-17 61.5 0.1 6.8e-08 32.6 0.0 3.6 3 1 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EKX45492.1 - 9.6e-17 60.8 0.8 4.6e-07 30.0 0.0 3.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ephrin_rec_like PF07699.13 EKX45493.1 - 3.9e-17 61.7 53.6 9.5e-05 22.1 2.4 5.7 2 1 4 6 6 6 6 Putative ephrin-receptor like NCD3G PF07562.14 EKX45493.1 - 9.6e-13 47.9 38.6 0.0012 18.8 3.6 5.1 4 1 0 5 5 5 4 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX45493.1 - 1.2e-05 25.6 40.2 0.029 14.8 4.2 6.9 2 2 3 6 6 6 4 TNFR/NGFR cysteine-rich region Furin-like_2 PF15913.5 EKX45493.1 - 0.1 12.7 29.6 0.092 12.9 5.5 3.3 1 1 1 3 3 3 0 Furin-like repeat, cysteine-rich VSP PF03302.13 EKX45493.1 - 0.3 9.9 44.3 0.83 8.4 15.3 2.5 1 1 1 2 2 2 0 Giardia variant-specific surface protein WD40 PF00400.32 EKX45494.1 - 5.3e-58 191.6 25.4 9.3e-09 35.8 0.1 7.0 7 0 0 7 7 7 7 WD domain, G-beta repeat WD40_like PF17005.5 EKX45494.1 - 5.2e-14 52.3 0.2 0.044 13.1 0.0 5.4 2 2 3 5 5 5 5 WD40-like domain Nup160 PF11715.8 EKX45494.1 - 2.9e-10 39.4 15.3 0.16 10.6 0.1 6.2 1 1 5 6 6 6 4 Nucleoporin Nup120/160 DUF1036 PF06282.11 EKX45494.1 - 4e-06 27.3 1.4 9.4 6.8 0.0 4.7 1 1 4 5 5 5 1 Protein of unknown function (DUF1036) DPPIV_N PF00930.21 EKX45494.1 - 4.5e-06 25.7 4.7 4.1 6.1 0.0 5.7 1 1 5 6 6 6 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Ge1_WD40 PF16529.5 EKX45494.1 - 6.1e-06 25.4 5.1 0.23 10.4 0.0 5.1 1 1 5 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 EKX45494.1 - 4.7e-05 23.6 8.3 6.1 7.2 0.2 5.4 1 1 5 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain OCD_Mu_crystall PF02423.15 EKX45494.1 - 6.2e-05 22.1 2.6 4.9 6.0 0.1 4.9 2 2 2 5 5 5 1 Ornithine cyclodeaminase/mu-crystallin family Fascin PF06268.13 EKX45494.1 - 0.00013 22.2 2.7 6.4 7.0 0.1 4.5 1 1 5 6 6 6 2 Fascin domain DUF4402 PF14352.6 EKX45494.1 - 0.00018 22.2 10.3 0.036 14.7 2.0 3.6 1 1 2 3 3 3 1 Domain of unknown function (DUF4402) PD40 PF07676.12 EKX45494.1 - 0.0006 19.7 0.0 16 5.5 0.0 5.5 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 EKX45494.1 - 0.0019 18.6 17.9 17 6.0 0.1 6.9 6 1 1 7 7 7 0 PQQ-like domain HARP PF07443.13 EKX45494.1 - 0.0022 17.6 0.3 8.8 6.1 0.0 3.9 5 0 0 5 5 5 2 HepA-related protein (HARP) DUF1494 PF07379.11 EKX45494.1 - 0.017 15.0 1.0 43 3.9 0.0 4.3 1 1 5 6 6 6 0 Protein of unknown function (DUF1494) BBS2_Mid PF14783.6 EKX45494.1 - 0.019 15.0 6.7 5 7.2 0.3 5.0 2 2 2 4 4 4 0 Ciliary BBSome complex subunit 2, middle region VID27 PF08553.10 EKX45494.1 - 0.14 11.2 1.1 2.1 7.3 0.3 2.5 1 1 1 2 2 2 0 VID27 C-terminal WD40-like domain Ribosomal_L28 PF00830.19 EKX45494.1 - 1.7 8.9 5.4 4.8 7.5 0.1 4.1 2 2 3 5 5 5 0 Ribosomal L28 family ART PF01129.18 EKX45495.1 - 1.3e-10 41.0 0.0 2e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase ADPrib_exo_Tox PF03496.14 EKX45495.1 - 1.2e-08 34.6 0.0 6.4e-08 32.2 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosyltransferase exoenzyme Ank_5 PF13857.6 EKX45495.1 - 0.0019 18.4 0.0 0.0055 17.0 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX45495.1 - 0.0029 18.1 0.0 0.0066 17.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX45495.1 - 0.0041 17.7 0.0 0.01 16.4 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX45495.1 - 0.014 15.8 0.0 0.068 13.8 0.0 2.2 1 0 0 1 1 1 0 Ankyrin repeat Ank PF00023.30 EKX45495.1 - 0.021 15.2 0.0 0.076 13.5 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeat LRR_6 PF13516.6 EKX45496.1 - 1.5e-08 34.0 14.2 0.84 9.8 0.0 7.7 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 EKX45496.1 - 7.4e-08 32.6 5.0 0.13 12.8 0.1 5.7 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX45496.1 - 0.054 14.1 10.4 14 6.7 0.4 6.2 5 1 0 5 5 5 0 Leucine Rich Repeat SAM_Ste50p PF09235.10 EKX45496.1 - 7.7 6.8 8.4 4.3 7.7 0.3 3.9 4 1 1 5 5 5 0 Ste50p, sterile alpha motif DUF5384 PF17358.2 EKX45497.1 - 4.9 7.2 15.9 1.9 8.5 12.6 2.0 1 1 0 1 1 1 0 Family of unknown function (DUF5384) FUN14 PF04930.15 EKX45498.1 - 1.3e-23 83.2 0.6 1.3e-23 83.2 0.6 2.0 2 1 0 2 2 2 1 FUN14 family Asp-B-Hydro_N PF05279.11 EKX45498.1 - 0.0083 16.2 12.1 0.051 13.6 12.1 1.9 1 1 0 1 1 1 1 Aspartyl beta-hydroxylase N-terminal region CRAL_TRIO PF00650.20 EKX45500.1 - 6.9e-17 61.6 0.1 1.1e-08 35.0 0.0 2.5 1 1 1 2 2 2 2 CRAL/TRIO domain ASH PF15780.5 EKX45501.1 - 6.9e-08 32.6 0.0 0.11 12.7 0.0 4.6 4 0 0 4 4 4 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin RimM PF01782.18 EKX45502.1 - 0.02 15.1 0.3 0.082 13.1 0.3 2.2 1 1 0 1 1 1 0 RimM N-terminal domain NPR3 PF03666.13 EKX45502.1 - 0.56 8.9 12.6 0.54 9.0 4.8 2.1 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 EKX45502.1 - 1.3 7.3 18.8 0.07 11.4 4.6 2.1 2 0 0 2 2 2 0 CDC45-like protein FYDLN_acid PF09538.10 EKX45502.1 - 2.7 8.7 19.5 2.9 8.6 6.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) SAP PF02037.27 EKX45503.1 - 7.1e-18 63.9 9.6 1.1e-13 50.5 1.5 2.8 2 1 0 2 2 2 2 SAP domain RRM_1 PF00076.22 EKX45503.1 - 2.2e-08 33.8 0.0 4.7e-07 29.5 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HeH PF12949.7 EKX45503.1 - 1.9e-06 27.5 1.4 0.00085 19.0 0.1 2.7 2 0 0 2 2 2 2 HeH/LEM domain Telomere_Sde2_2 PF13297.6 EKX45503.1 - 0.00087 18.9 5.4 0.0064 16.1 1.1 2.6 2 0 0 2 2 2 1 Telomere stability C-terminal Nup35_RRM_2 PF14605.6 EKX45503.1 - 0.0085 16.1 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DIMCO_N PF16844.5 EKX45503.1 - 0.032 14.6 2.0 8.1 6.9 0.1 2.5 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal TetR_C_7 PF14246.6 EKX45503.1 - 0.058 13.4 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain DUF1866 PF08952.11 EKX45503.1 - 0.086 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) Armet PF10208.9 EKX45503.1 - 0.11 12.5 0.2 0.68 9.9 0.0 2.0 2 0 0 2 2 2 0 Degradation arginine-rich protein for mis-folding Rho_N PF07498.12 EKX45503.1 - 0.12 12.4 3.3 0.12 12.3 0.7 2.2 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain GT87 PF09594.10 EKX45504.1 - 0.1 12.3 3.1 0.14 11.8 3.1 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 87 Cpn60_TCP1 PF00118.24 EKX45505.1 - 1.8e-90 304.0 14.3 5.8e-90 302.3 14.3 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family JmjN PF02375.17 EKX45506.1 - 0.055 13.4 1.4 1.1 9.3 0.2 2.4 2 0 0 2 2 2 0 jmjN domain FIIND PF13553.6 EKX45506.1 - 0.057 12.8 0.2 0.085 12.2 0.2 1.2 1 0 0 1 1 1 0 Function to find Actin_micro PF17003.5 EKX45506.1 - 0.094 11.9 1.5 0.14 11.3 1.5 1.2 1 0 0 1 1 1 0 Putative actin-like family Paramyxo_PNT PF14320.6 EKX45506.1 - 0.19 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoprotein P region PNT disordered bZIP_1 PF00170.21 EKX45507.1 - 1e-07 32.0 6.0 1.7e-07 31.2 6.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EKX45507.1 - 1.4e-07 31.5 6.5 1.4e-07 31.5 6.5 1.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 EKX45507.1 - 0.0014 19.1 1.2 0.0024 18.3 1.2 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor PhyH PF05721.13 EKX45508.1 - 8.2e-11 42.6 0.0 1e-10 42.3 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Aminotran_5 PF00266.19 EKX45509.1 - 1.7e-54 185.2 0.0 1.1e-46 159.5 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EKX45509.1 - 6.3e-07 28.3 0.0 8.9e-07 27.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EKX45509.1 - 1.8e-05 24.1 0.0 2.8e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EKX45509.1 - 5.3e-05 22.7 0.2 7.8e-05 22.1 0.2 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Bromodomain PF00439.25 EKX45510.1 - 2.5e-20 72.3 0.0 2.8e-20 72.2 0.0 1.0 1 0 0 1 1 1 1 Bromodomain TBP PF00352.21 EKX45512.1 - 2.1e-16 59.6 0.0 3.9e-11 42.7 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) Zn_clus PF00172.18 EKX45513.1 - 4.2e-15 55.6 53.1 1.6e-05 24.9 10.0 3.7 3 1 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 EKX45514.1 - 5.3e-15 55.2 53.0 1.1e-05 25.5 9.6 3.6 3 1 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain TBP PF00352.21 EKX45516.1 - 1.4e-16 60.2 0.0 2.7e-11 43.3 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) Chordopox_A30L PF06015.12 EKX45517.1 - 0.033 14.0 3.9 0.059 13.2 0.1 3.1 3 0 0 3 3 3 0 Chordopoxvirus A30L protein Laminin_II PF06009.12 EKX45517.1 - 0.047 13.7 1.1 0.047 13.7 1.1 3.2 3 1 0 3 3 3 0 Laminin Domain II Jnk-SapK_ap_N PF09744.9 EKX45517.1 - 0.096 12.9 4.4 1.5 9.0 0.2 2.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF4164 PF13747.6 EKX45517.1 - 0.66 10.3 4.2 0.67 10.3 0.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) DUF2508 PF10704.9 EKX45517.1 - 0.92 9.7 4.7 1.5 9.1 2.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) NPV_P10 PF05531.12 EKX45517.1 - 0.98 9.9 5.0 1.6 9.3 0.2 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein TBP PF00352.21 EKX45518.1 - 1.5e-66 220.4 0.7 3e-33 113.6 0.2 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EKX45518.1 - 2.5e-05 24.3 0.0 0.11 12.6 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Peptidase_C2 PF00648.21 EKX45519.1 - 8.3e-56 189.2 0.0 1.2e-55 188.7 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 EKX45519.1 - 3.4e-24 85.7 0.0 1.3e-14 54.7 0.0 2.6 2 1 0 2 2 2 2 Calpain large subunit, domain III UIM PF02809.20 EKX45519.1 - 0.001 18.8 4.7 0.0036 17.1 4.7 2.0 1 0 0 1 1 1 1 Ubiquitin interaction motif RNA_pol_Rpc34 PF05158.12 EKX45520.1 - 1.2e-24 87.3 0.3 2.3e-15 56.8 0.0 2.4 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit Fez1 PF06818.15 EKX45521.1 - 0.0019 18.7 20.8 0.0019 18.7 20.8 4.9 1 1 2 4 4 4 1 Fez1 DUF3584 PF12128.8 EKX45521.1 - 0.1 10.1 56.9 0.89 7.0 8.8 3.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF4407 PF14362.6 EKX45521.1 - 0.47 9.7 51.7 1.6 8.0 2.6 4.5 1 1 5 6 6 6 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 EKX45521.1 - 0.5 10.4 63.9 0.051 13.7 7.6 4.6 1 1 2 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus AAA_13 PF13166.6 EKX45521.1 - 4.9 5.7 48.4 0.054 12.1 16.3 3.3 2 1 1 4 4 4 0 AAA domain WD40_alt PF14077.6 EKX45521.1 - 6.2 6.8 9.4 2.6 8.0 0.1 4.5 3 2 1 4 4 4 0 Alternative WD40 repeat motif Kelch_3 PF13415.6 EKX45522.1 - 2.6e-20 72.2 11.6 7.6e-06 26.1 0.0 6.0 6 0 0 6 6 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EKX45522.1 - 2.6e-17 62.4 0.3 0.0074 16.3 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 EKX45522.1 - 4e-16 58.8 6.7 0.0027 17.7 0.0 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 EKX45522.1 - 1.7e-15 56.3 10.8 8e-07 28.8 0.5 5.8 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 EKX45522.1 - 2.9e-10 39.6 7.1 0.0039 16.8 0.3 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 EKX45522.1 - 2.9e-06 27.4 6.1 0.29 11.5 0.0 5.4 4 1 1 5 5 5 1 Kelch motif MDM10 PF12519.8 EKX45522.1 - 5.2e-05 22.3 7.2 7.4e-05 21.8 7.2 1.2 1 0 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 DDHD PF02862.17 EKX45522.1 - 6e-05 23.3 7.9 8e-05 22.9 7.9 1.2 1 0 0 1 1 1 1 DDHD domain Presenilin PF01080.17 EKX45522.1 - 0.0013 17.6 20.8 0.0017 17.2 20.8 1.1 1 0 0 1 1 1 1 Presenilin EPL1 PF10513.9 EKX45522.1 - 0.0019 18.6 13.8 0.004 17.6 13.8 1.6 1 0 0 1 1 1 1 Enhancer of polycomb-like PAT1 PF09770.9 EKX45522.1 - 0.0034 15.7 32.1 0.0045 15.4 32.1 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF5308 PF17233.2 EKX45522.1 - 0.0041 17.3 7.9 0.007 16.6 7.9 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5308) Pex14_N PF04695.13 EKX45522.1 - 0.013 16.1 32.3 0.023 15.4 32.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MCM_bind PF09739.9 EKX45522.1 - 0.018 13.5 18.9 0.025 13.0 18.9 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor BORG_CEP PF14957.6 EKX45522.1 - 0.03 15.5 8.9 0.051 14.7 8.9 1.4 1 0 0 1 1 1 0 Cdc42 effector NPR3 PF03666.13 EKX45522.1 - 0.034 13.0 17.1 0.045 12.5 17.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Otopetrin PF03189.13 EKX45522.1 - 0.035 12.9 5.9 0.047 12.5 5.9 1.1 1 0 0 1 1 1 0 Otopetrin Nop53 PF07767.11 EKX45522.1 - 0.041 13.3 30.3 0.055 12.9 30.3 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) ABC2_membrane_2 PF12679.7 EKX45522.1 - 0.043 13.1 0.3 0.061 12.6 0.3 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein CPSF100_C PF13299.6 EKX45522.1 - 0.045 13.9 11.9 0.08 13.1 11.9 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CCDC53 PF10152.9 EKX45522.1 - 0.06 13.8 22.7 0.1 13.0 22.7 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Tim54 PF11711.8 EKX45522.1 - 0.062 12.1 17.2 0.097 11.4 17.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TFIIA PF03153.13 EKX45522.1 - 0.092 12.7 51.4 0.15 12.0 51.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 EKX45522.1 - 0.11 10.8 19.6 0.15 10.3 19.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2828 PF11443.8 EKX45522.1 - 0.12 10.4 18.3 0.17 9.9 18.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Cellulose_synt PF03552.14 EKX45522.1 - 0.13 10.7 6.8 0.17 10.3 6.8 1.1 1 0 0 1 1 1 0 Cellulose synthase eIF-3_zeta PF05091.12 EKX45522.1 - 0.13 11.2 28.3 0.19 10.7 28.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RIC3 PF15361.6 EKX45522.1 - 0.16 12.3 12.7 0.34 11.3 12.7 1.5 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 VIT1 PF01988.19 EKX45522.1 - 0.18 11.7 0.8 0.26 11.1 0.8 1.4 1 0 0 1 1 1 0 VIT family DUF2347 PF09804.9 EKX45522.1 - 0.18 11.3 7.7 0.27 10.8 7.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) PepSY_TM PF03929.16 EKX45522.1 - 0.21 11.2 8.0 0.41 10.3 8.0 1.5 1 0 0 1 1 1 0 PepSY-associated TM region SpoIIP PF07454.11 EKX45522.1 - 0.24 10.8 23.6 0.36 10.3 23.6 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4638 PF15472.6 EKX45522.1 - 0.33 10.7 21.0 0.48 10.1 21.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Zip PF02535.22 EKX45522.1 - 0.34 10.1 8.4 0.52 9.5 8.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4776 PF16003.5 EKX45522.1 - 0.34 9.8 21.5 0.55 9.2 21.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) SAPS PF04499.15 EKX45522.1 - 0.41 9.4 14.5 0.55 9.0 14.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Velvet PF11754.8 EKX45522.1 - 0.44 10.5 18.9 0.67 9.8 18.9 1.2 1 0 0 1 1 1 0 Velvet factor DUF4045 PF13254.6 EKX45522.1 - 0.56 9.8 18.7 0.8 9.3 18.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Ndc1_Nup PF09531.10 EKX45522.1 - 0.62 8.7 14.6 0.82 8.3 14.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AAA_11 PF13086.6 EKX45522.1 - 0.73 9.6 20.5 1.1 9.0 20.5 1.2 1 0 0 1 1 1 0 AAA domain UPF0560 PF10577.9 EKX45522.1 - 0.78 8.2 29.9 1.2 7.5 29.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 RR_TM4-6 PF06459.12 EKX45522.1 - 0.81 9.5 26.9 1.2 8.9 26.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 EKX45522.1 - 0.83 8.6 23.2 1.2 8.1 23.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Gti1_Pac2 PF09729.9 EKX45522.1 - 0.89 9.6 20.4 1.5 8.9 20.4 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family FAM60A PF15396.6 EKX45522.1 - 0.9 9.5 18.8 1.5 8.8 18.8 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Lin-8 PF03353.15 EKX45522.1 - 1.1 8.8 28.5 1.6 8.2 28.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Endostatin PF06482.11 EKX45522.1 - 1.3 8.5 21.5 2.4 7.5 21.5 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF4050 PF13259.6 EKX45522.1 - 1.6 9.0 23.0 2.6 8.4 23.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) TERB2 PF15101.6 EKX45522.1 - 1.8 8.5 30.8 3.3 7.7 30.8 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Sec62 PF03839.16 EKX45522.1 - 2.4 7.6 19.1 4.1 6.8 19.1 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 AUX_IAA PF02309.16 EKX45522.1 - 2.6 7.8 14.1 3.9 7.3 14.1 1.2 1 0 0 1 1 1 0 AUX/IAA family Connexin PF00029.19 EKX45522.1 - 3.5 7.3 18.0 5.6 6.6 18.0 1.3 1 0 0 1 1 1 0 Connexin PIP5K PF01504.18 EKX45522.1 - 4.1 6.6 18.6 6 6.0 18.6 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase ORC_WH_C PF18137.1 EKX45522.1 - 4.3 7.4 21.0 7.7 6.6 21.0 1.4 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal FAM176 PF14851.6 EKX45522.1 - 4.6 6.9 13.2 9.6 5.9 13.2 1.6 1 0 0 1 1 1 0 FAM176 family DUF2201_N PF13203.6 EKX45522.1 - 4.7 6.7 18.6 7.2 6.1 18.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain LTV PF04180.14 EKX45522.1 - 4.7 6.8 28.9 6.7 6.3 28.9 1.1 1 0 0 1 1 1 0 Low temperature viability protein DUF913 PF06025.12 EKX45522.1 - 6 5.7 17.3 8.4 5.3 17.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CCSAP PF15748.5 EKX45522.1 - 8 6.6 29.6 12 6.0 29.6 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated GREB1 PF15782.5 EKX45522.1 - 8.8 3.3 24.1 12 2.9 24.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LAP1C PF05609.12 EKX45522.1 - 9.8 5.1 25.4 14 4.6 25.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SAP PF02037.27 EKX45524.1 - 8.2e-11 41.4 1.1 1.4e-10 40.7 1.1 1.3 1 0 0 1 1 1 1 SAP domain Rho_N PF07498.12 EKX45524.1 - 0.026 14.5 0.6 0.24 11.4 0.2 2.3 2 1 0 2 2 2 0 Rho termination factor, N-terminal domain DUF1977 PF09320.11 EKX45525.1 - 0.36 11.1 5.4 0.12 12.6 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1977) CCDC-167 PF15188.6 EKX45525.1 - 0.92 9.9 10.1 6.6 7.2 3.6 2.5 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Histone_HNS PF00816.21 EKX45525.1 - 7.4 7.5 8.7 4.1 8.3 0.8 2.3 1 1 1 2 2 2 0 H-NS histone family PEX11 PF05648.14 EKX45526.1 - 2.7e-05 23.7 0.0 3.8e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF1378 PF07125.11 EKX45526.1 - 0.2 11.8 2.2 0.81 9.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1378) IQ PF00612.27 EKX45527.1 - 0.00028 20.4 5.7 0.011 15.4 0.6 3.2 2 0 0 2 2 2 2 IQ calmodulin-binding motif ADH_N PF08240.12 EKX45528.1 - 1.6e-08 34.4 0.4 9.9e-07 28.6 0.0 2.6 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EKX45528.1 - 1.9e-07 31.1 0.1 4.6e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EKX45528.1 - 0.04 15.0 0.0 0.15 13.1 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase RAMPs PF03787.15 EKX45528.1 - 0.1 12.6 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 RAMP superfamily DUF5585 PF17823.1 EKX45529.1 - 0.022 13.8 1.0 0.024 13.6 1.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) ADH_N PF08240.12 EKX45531.1 - 7.3e-10 38.7 0.6 3.9e-08 33.1 0.0 2.6 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EKX45531.1 - 1.6e-07 31.4 0.0 3.6e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EKX45531.1 - 0.052 14.6 0.1 0.2 12.7 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Ion_trans PF00520.31 EKX45532.1 - 4.1e-33 114.6 11.2 5.6e-33 114.2 11.2 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX45532.1 - 8.7e-10 38.4 1.0 8.7e-10 38.4 1.0 2.9 3 0 0 3 3 3 1 Ion channel EFhand_Ca_insen PF08726.10 EKX45532.1 - 0.17 12.0 0.3 0.42 10.7 0.3 1.7 1 0 0 1 1 1 0 Ca2+ insensitive EF hand SurA_N_2 PF13623.6 EKX45532.1 - 0.92 9.4 7.6 1.5 8.6 0.1 3.1 3 0 0 3 3 3 0 SurA N-terminal domain DUF4349 PF14257.6 EKX45533.1 - 0.19 11.1 3.0 1.7 8.0 0.1 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4349) SAS-6_N PF16531.5 EKX45534.1 - 8.8e-29 99.9 3.8 2.2e-28 98.6 3.8 1.7 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal Tropomyosin_1 PF12718.7 EKX45534.1 - 0.0069 16.5 5.6 0.0069 16.5 5.6 4.3 4 0 0 4 4 4 2 Tropomyosin like DUF3552 PF12072.8 EKX45534.1 - 0.011 15.1 3.1 0.011 15.1 3.1 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF3552) Lebercilin PF15619.6 EKX45534.1 - 0.24 11.0 43.7 0.64 9.6 3.7 4.2 4 0 0 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease Tropomyosin PF00261.20 EKX45534.1 - 5 6.4 40.7 0.11 11.8 15.6 3.6 3 1 0 3 3 3 0 Tropomyosin DUF2937 PF11157.8 EKX45534.1 - 9.6 5.9 10.3 0.37 10.5 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF2897 PF11446.8 EKX45535.1 - 0.66 9.9 2.3 1.4 8.9 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) RWP-RK PF02042.15 EKX45536.1 - 0.00031 20.7 1.2 0.00051 20.0 1.2 1.3 1 0 0 1 1 1 1 RWP-RK domain Dendrin PF15498.6 EKX45536.1 - 0.17 10.6 4.6 0.24 10.1 4.6 1.1 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin PH PF00169.29 EKX45537.1 - 0.00018 22.0 0.2 0.0075 16.8 0.1 2.3 2 0 0 2 2 2 2 PH domain SET PF00856.28 EKX45538.1 - 1.4e-12 48.4 0.0 1.4e-12 48.4 0.0 2.2 3 0 0 3 3 3 1 SET domain Rep_fac-A_C PF08646.10 EKX45538.1 - 0.0046 16.7 0.1 0.012 15.3 0.1 1.7 1 0 0 1 1 1 1 Replication factor-A C terminal domain SAF PF08666.12 EKX45538.1 - 0.076 13.6 0.0 1.2 9.8 0.0 2.5 2 0 0 2 2 2 0 SAF domain TPR_12 PF13424.6 EKX45538.1 - 0.12 12.7 0.0 3 8.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat VWC PF00093.18 EKX45538.1 - 2 8.8 10.6 19 5.6 0.2 3.1 2 0 0 2 2 2 0 von Willebrand factor type C domain NOC3p PF07540.11 EKX45539.1 - 2.8e-29 101.4 0.2 1.3e-28 99.3 0.2 2.3 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 EKX45539.1 - 3.7e-20 72.6 0.4 3.7e-20 72.6 0.4 2.8 4 0 0 4 4 4 1 CBF/Mak21 family RasGEF_N_2 PF14663.6 EKX45539.1 - 0.029 14.8 0.4 0.39 11.1 0.1 2.9 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Mg_trans_NIPA PF05653.14 EKX45540.1 - 5.4e-55 186.6 16.3 6.6e-55 186.3 16.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EKX45540.1 - 1.1e-06 28.9 1.2 1.1e-06 28.9 1.2 3.0 2 1 1 3 3 3 1 EamA-like transporter family Saf_2TM PF18303.1 EKX45540.1 - 0.042 13.4 0.5 0.042 13.4 0.5 1.9 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain DUF1077 PF06417.12 EKX45540.1 - 0.11 12.5 6.4 0.22 11.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1077) EF-hand_6 PF13405.6 EKX45541.1 - 6.5e-31 103.6 1.9 1.4e-05 24.6 0.0 6.7 6 0 0 6 6 6 5 EF-hand domain EF-hand_1 PF00036.32 EKX45541.1 - 1.3e-30 102.6 0.1 3.2e-05 23.2 0.1 6.7 6 0 0 6 6 6 6 EF hand EF-hand_7 PF13499.6 EKX45541.1 - 9e-30 102.9 1.2 8.2e-10 39.0 0.0 4.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EKX45541.1 - 8.9e-23 78.7 0.4 1.1e-05 24.6 0.0 6.9 7 0 0 7 7 7 5 EF hand EF-hand_8 PF13833.6 EKX45541.1 - 1.5e-17 63.2 1.4 1.8e-06 27.7 0.0 5.5 4 2 2 6 6 6 5 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX45541.1 - 1.2e-10 41.6 0.0 0.017 15.4 0.0 4.0 4 1 0 4 4 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 EKX45541.1 - 5.7e-05 22.9 1.0 0.14 12.1 0.0 4.8 5 0 0 5 5 5 1 EF hand EF-hand_4 PF12763.7 EKX45541.1 - 6.6e-05 22.8 0.0 2.2 8.3 0.0 4.0 3 1 1 4 4 4 1 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 EKX45541.1 - 0.002 18.3 0.0 5.8 7.2 0.0 3.4 3 0 0 3 3 3 1 Dockerin type I domain EF-hand_9 PF14658.6 EKX45541.1 - 0.003 17.9 0.1 0.54 10.6 0.0 3.5 3 1 0 3 3 3 1 EF-hand domain RuvA_C PF07499.13 EKX45541.1 - 0.0046 17.4 0.9 11 6.6 0.1 3.4 3 0 0 3 3 3 1 RuvA, C-terminal domain Caleosin PF05042.13 EKX45541.1 - 0.13 12.1 0.3 4.4 7.2 0.0 3.2 4 1 0 4 4 4 0 Caleosin related protein DUF2999 PF11212.8 EKX45541.1 - 0.21 11.9 0.0 3.7 7.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) SelP_N PF04592.14 EKX45541.1 - 6.2 6.1 19.0 0.066 12.6 10.9 1.7 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Hanta_G2 PF01561.16 EKX45542.1 - 0.046 12.4 0.1 0.065 11.9 0.1 1.1 1 0 0 1 1 1 0 Hantavirus glycoprotein G2 PAS_9 PF13426.7 EKX45543.1 - 3.7e-06 27.1 0.0 0.15 12.3 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 EKX45543.1 - 0.00092 19.2 0.0 0.74 9.8 0.0 2.8 2 0 0 2 2 2 2 PAS fold KTSC PF13619.6 EKX45543.1 - 0.089 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 KTSC domain DUF2358 PF10184.9 EKX45546.1 - 1.9e-16 60.3 0.0 2.4e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 EKX45546.1 - 0.00033 21.3 0.0 0.00044 20.9 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EKX45546.1 - 0.1 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase GTA_holin_3TM PF11351.8 EKX45548.1 - 6 7.4 6.8 12 6.5 6.8 1.4 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release KfrA_N PF11740.8 EKX45548.1 - 9 7.0 15.8 15 6.3 10.2 2.2 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term U-box PF04564.15 EKX45549.1 - 2.7e-11 43.5 0.0 3e-11 43.3 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX45549.1 - 1.7e-05 24.5 0.1 2.5e-05 24.0 0.1 1.1 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EKX45549.1 - 0.0067 16.4 0.0 0.0098 15.9 0.0 1.3 1 0 0 1 1 1 1 RING-type zinc-finger TM231 PF10149.9 EKX45550.1 - 3e-59 200.8 2.5 3.4e-59 200.7 2.5 1.0 1 0 0 1 1 1 1 Transmembrane protein 231 zf-ANAPC11 PF12861.7 EKX45552.1 - 0.11 12.6 0.3 0.59 10.2 0.1 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger MGAT2 PF05060.14 EKX45553.1 - 8.9e-16 57.9 0.0 9.8e-16 57.8 0.0 1.0 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) NMT1 PF09084.11 EKX45554.1 - 4.9e-13 49.5 0.0 9.2e-12 45.4 0.0 2.2 2 0 0 2 2 2 1 NMT1/THI5 like CCDC24 PF15669.5 EKX45554.1 - 0.25 11.2 4.0 0.4 10.5 4.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family WD40 PF00400.32 EKX45555.1 - 1.9e-46 155.0 7.9 3.2e-06 27.8 0.8 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX45555.1 - 3.9e-15 55.9 0.2 0.0035 17.6 0.0 5.8 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EKX45555.1 - 1e-05 25.5 0.0 0.062 13.2 0.0 3.3 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EKX45555.1 - 0.008 15.2 0.0 14 4.5 0.0 4.1 1 1 5 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EKX45555.1 - 0.039 12.5 0.1 0.59 8.6 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain DASH_Duo1 PF08651.10 EKX45556.1 - 0.078 12.8 1.1 19 5.1 0.1 3.0 2 1 1 3 3 3 0 DASH complex subunit Duo1 TraG_N PF07916.11 EKX45556.1 - 9.3 5.0 6.6 15 4.3 6.6 1.3 1 0 0 1 1 1 0 TraG-like protein, N-terminal region MFS18 PF17352.2 EKX45557.1 - 0.01 16.2 4.5 0.013 15.9 4.5 1.2 1 0 0 1 1 1 0 Male Flower Specific protein 18 Kinesin PF00225.23 EKX45559.1 - 4.5e-110 367.7 0.1 5.1e-110 367.5 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX45559.1 - 1.1e-23 83.8 0.0 1.9e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding AAA_22 PF13401.6 EKX45559.1 - 0.087 13.1 0.9 0.38 11.0 0.2 2.2 2 1 0 2 2 2 0 AAA domain WD40 PF00400.32 EKX45560.1 - 1.1e-37 127.4 5.1 7.3e-10 39.3 0.2 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX45560.1 - 6.7e-11 42.3 0.0 0.005 17.1 0.0 3.2 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EKX45560.1 - 0.00088 19.2 0.0 0.0046 16.9 0.0 1.8 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EKX45560.1 - 0.0023 16.6 0.0 0.31 9.6 0.0 2.3 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EKX45560.1 - 0.0043 16.1 0.0 0.36 9.7 0.1 2.9 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein C2 PF00168.30 EKX45562.1 - 1.3e-05 25.5 0.5 0.096 13.0 0.0 5.7 6 0 0 6 6 6 1 C2 domain VHS PF00790.19 EKX45565.1 - 4e-06 26.7 0.0 4.7e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 VHS domain OTU PF02338.19 EKX45566.1 - 3.2e-07 30.9 0.1 8.1e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease HTH_33 PF13592.6 EKX45567.1 - 0.013 15.1 0.1 0.69 9.6 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn helix Collagen PF01391.18 EKX45568.1 - 1.1e-14 53.9 69.0 3e-09 36.5 27.9 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) TraL PF07178.11 EKX45568.1 - 0.062 13.8 0.0 0.098 13.1 0.0 1.2 1 0 0 1 1 1 0 TraL protein eIF_4EBP PF05456.11 EKX45568.1 - 0.69 9.9 3.4 1.2 9.1 3.2 1.4 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Rhomboid PF01694.22 EKX45570.1 - 5e-07 29.8 2.3 8.5e-07 29.1 2.3 1.4 1 1 0 1 1 1 1 Rhomboid family PIP5K PF01504.18 EKX45571.1 - 1.3e-24 86.9 0.5 6.4e-23 81.4 0.0 2.8 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase PH PF00169.29 EKX45571.1 - 1.2e-06 28.9 0.1 5.1e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 PH domain EF-hand_1 PF00036.32 EKX45572.1 - 4.7e-18 63.3 4.2 0.00033 20.0 0.1 4.7 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EKX45572.1 - 4.3e-14 51.2 9.2 0.0012 18.6 0.1 4.7 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.6 EKX45572.1 - 3.1e-11 43.6 22.1 6.2e-05 23.4 3.1 3.2 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EKX45572.1 - 3e-10 39.1 10.7 0.0026 17.2 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EKX45572.1 - 3.3e-09 36.5 7.9 0.00027 20.7 0.1 3.9 4 0 0 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX45572.1 - 0.089 13.1 8.6 9.6 6.6 0.0 3.9 2 1 2 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region Prismane PF03063.20 EKX45573.1 - 4.7e-127 424.8 0.0 5.5e-127 424.5 0.0 1.0 1 0 0 1 1 1 1 Prismane/CO dehydrogenase family DUF459 PF04311.13 EKX45573.1 - 0.14 11.1 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF459) AAA PF00004.29 EKX45574.1 - 0.0054 17.2 0.0 0.01 16.2 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX45574.1 - 0.094 13.1 0.1 0.26 11.6 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain Glyco_transf_8 PF01501.20 EKX45575.1 - 0.025 14.2 0.6 0.076 12.6 0.6 1.8 1 1 0 1 1 1 0 Glycosyl transferase family 8 TPR_16 PF13432.6 EKX45576.1 - 0.001 19.6 1.6 0.0029 18.2 1.6 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX45576.1 - 0.0054 17.5 1.2 0.025 15.4 0.3 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX45576.1 - 0.012 15.7 0.3 0.7 10.2 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat p25-alpha PF05517.12 EKX45576.1 - 0.099 12.8 0.2 24 5.0 0.0 2.6 2 0 0 2 2 2 0 p25-alpha TPR_19 PF14559.6 EKX45576.1 - 0.12 12.8 0.2 0.37 11.3 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat PGAP1 PF07819.13 EKX45578.1 - 6.4e-05 22.8 0.0 0.00024 20.9 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein Palm_thioest PF02089.15 EKX45578.1 - 0.087 12.6 0.0 0.099 12.5 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase LCAT PF02450.15 EKX45578.1 - 0.28 10.3 0.0 0.46 9.6 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 EKX45578.1 - 0.3 11.7 2.8 0.43 11.2 2.6 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family tRNA-synt_1 PF00133.22 EKX45579.1 - 7.5e-194 645.4 0.5 9.1e-194 645.1 0.5 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EKX45579.1 - 2.7e-30 105.3 0.1 5.8e-30 104.3 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EKX45579.1 - 4.7e-22 78.3 0.0 8.3e-13 47.8 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.14 EKX45579.1 - 6.3e-07 29.1 2.2 1.2e-06 28.2 2.2 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.6 EKX45579.1 - 0.0003 20.4 0.0 0.00059 19.4 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 EKX45579.1 - 0.00088 18.7 0.0 0.84 8.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain SET PF00856.28 EKX45580.1 - 2.8e-13 50.6 0.0 6.6e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 SET domain PIH1_CS PF18201.1 EKX45580.1 - 0.00035 20.9 0.0 0.00088 19.6 0.0 1.7 1 1 0 1 1 1 1 PIH1 CS-like domain TIG PF01833.24 EKX45581.1 - 5.3e-10 39.2 32.0 0.33 11.1 0.3 11.8 12 0 0 12 12 12 6 IPT/TIG domain RRM_1 PF00076.22 EKX45582.1 - 5.3e-18 64.6 0.0 5.3e-09 35.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EKX45582.1 - 0.00075 19.5 0.0 0.07 13.2 0.0 2.6 2 0 0 2 2 2 1 RNA binding motif DUF4651 PF15513.6 EKX45582.1 - 0.0054 16.5 0.1 7.8 6.4 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF4651) Nup35_RRM_2 PF14605.6 EKX45582.1 - 0.0081 16.1 0.1 0.4 10.7 0.0 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EKX45582.1 - 0.074 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif GYF_2 PF14237.6 EKX45583.1 - 1.4e-05 24.8 0.2 4.3e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 GYF domain 2 FliG_C PF01706.16 EKX45583.1 - 0.29 11.4 1.9 0.42 10.8 0.3 2.1 2 0 0 2 2 2 0 FliG C-terminal domain Gpi16 PF04113.14 EKX45584.1 - 1.6e-73 248.1 0.0 2.2e-73 247.6 0.0 1.1 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Nab2 PF11517.8 EKX45584.1 - 0.19 12.0 0.0 0.37 11.1 0.0 1.4 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) WD40 PF00400.32 EKX45587.1 - 9.6e-09 35.7 5.1 0.032 15.1 0.1 6.4 7 0 0 7 7 7 1 WD domain, G-beta repeat BBS2_Mid PF14783.6 EKX45587.1 - 0.0013 18.8 0.0 0.53 10.3 0.0 3.4 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.11 EKX45587.1 - 0.0043 16.9 0.1 0.67 9.8 0.0 3.4 3 1 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 EKX45587.1 - 0.0083 16.4 0.0 0.17 12.2 0.0 3.0 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 EKX45587.1 - 0.046 13.7 0.3 0.2 11.6 0.1 2.2 2 0 0 2 2 2 0 PQQ enzyme repeat TPR_8 PF13181.6 EKX45588.1 - 0.00024 21.1 10.5 0.0089 16.2 0.1 4.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX45588.1 - 0.00025 20.7 10.1 0.74 9.7 0.1 4.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX45588.1 - 0.0021 17.7 0.4 8.6 6.1 0.1 4.5 4 1 1 5 5 5 1 TPR repeat TPR_2 PF07719.17 EKX45588.1 - 0.0033 17.4 12.4 0.26 11.5 0.0 5.7 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX45588.1 - 0.032 14.6 0.4 2.4 8.7 0.0 3.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX45588.1 - 0.098 13.0 1.2 3 8.2 0.1 3.6 3 2 1 4 4 4 0 Tetratricopeptide repeat DUF4398 PF14346.6 EKX45588.1 - 1 10.0 7.3 2.3 8.9 2.1 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF4398) Guanylate_cyc PF00211.20 EKX45589.1 - 2.9e-12 46.6 0.0 3.7e-12 46.2 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain NFACT-R_1 PF05670.13 EKX45590.1 - 4e-42 143.3 0.1 7.7e-42 142.4 0.0 1.5 2 0 0 2 2 2 1 NFACT protein RNA binding domain Exonuc_VII_L PF02601.15 EKX45591.1 - 0.02 14.5 2.1 0.027 14.1 2.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.14 EKX45591.1 - 2.1 8.7 12.0 4.3 7.7 12.0 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) APG6_N PF17675.1 EKX45591.1 - 3 8.4 15.0 0.91 10.1 12.0 1.6 2 0 0 2 2 2 0 Apg6 coiled-coil region zf-C3HC4_3 PF13920.6 EKX45592.1 - 4.8e-13 48.7 3.0 4.8e-13 48.7 3.0 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX45592.1 - 4.6e-06 26.4 3.6 4.6e-06 26.4 3.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX45592.1 - 2.8e-05 23.9 4.5 8e-05 22.4 4.5 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EKX45592.1 - 0.00048 20.4 6.1 0.00048 20.4 6.1 2.5 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX45592.1 - 0.012 15.4 5.6 0.029 14.2 5.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX45592.1 - 0.013 15.4 4.7 0.013 15.4 4.7 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EKX45592.1 - 0.016 15.4 4.2 0.016 15.4 4.2 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RICTOR_V PF14668.6 EKX45592.1 - 0.16 12.2 0.1 0.4 11.0 0.1 1.6 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 DUF1644 PF07800.12 EKX45592.1 - 2.6 8.1 6.3 4.2 7.4 1.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1644) LRAT PF04970.13 EKX45594.1 - 0.11 12.8 0.5 0.2 11.9 0.2 1.5 2 0 0 2 2 2 0 Lecithin retinol acyltransferase DUF1187 PF06688.11 EKX45594.1 - 0.13 12.6 0.0 0.54 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1187) CENP-F_leu_zip PF10473.9 EKX45595.1 - 0.00029 20.9 8.9 0.00082 19.4 8.8 1.7 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 JAKMIP_CC3 PF16034.5 EKX45595.1 - 0.0018 18.2 5.0 0.002 18.1 5.0 1.2 1 0 0 1 1 1 1 JAKMIP CC3 domain Golgin_A5 PF09787.9 EKX45595.1 - 0.0025 17.4 5.7 0.0029 17.1 5.7 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 PspA_IM30 PF04012.12 EKX45595.1 - 0.011 15.3 5.8 0.02 14.5 5.9 1.4 1 1 0 1 1 1 0 PspA/IM30 family LPP PF04728.13 EKX45595.1 - 0.027 14.8 2.1 25 5.4 3.0 3.2 1 1 1 2 2 2 0 Lipoprotein leucine-zipper TMF_TATA_bd PF12325.8 EKX45595.1 - 0.038 14.2 8.7 0.084 13.1 7.0 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding ABC_tran_Xtn PF12848.7 EKX45595.1 - 0.045 13.8 6.4 0.068 13.2 6.4 1.3 1 0 0 1 1 1 0 ABC transporter BLOC1_2 PF10046.9 EKX45595.1 - 0.057 13.7 1.3 0.057 13.7 1.3 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF244 PF03112.14 EKX45595.1 - 0.18 11.6 2.0 7 6.5 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized protein family (ORF7) DUF TolA_bind_tri PF16331.5 EKX45595.1 - 0.25 11.4 14.0 0.15 12.2 3.2 2.8 1 1 1 2 2 2 0 TolA binding protein trimerisation TMPIT PF07851.13 EKX45595.1 - 0.33 10.2 3.8 0.36 10.0 3.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein FlaC_arch PF05377.11 EKX45595.1 - 0.35 11.3 3.3 1.6 9.2 0.2 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Cep57_CLD_2 PF14197.6 EKX45595.1 - 1 9.5 10.4 3 8.0 10.2 2.0 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 CC2-LZ PF16516.5 EKX45595.1 - 1.7 9.0 12.2 8.9 6.7 0.7 2.4 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator GIT_CC PF16559.5 EKX45595.1 - 2.2 8.2 7.5 0.86 9.5 0.5 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.15 EKX45595.1 - 3.5 7.5 11.0 0.38 10.5 3.3 2.3 1 1 1 2 2 2 0 Septum formation initiator Chorion_2 PF03964.15 EKX45597.1 - 0.19 12.6 2.8 0.53 11.1 2.8 1.8 1 0 0 1 1 1 0 Chorion family 2 Seryl_tRNA_N PF02403.22 EKX45597.1 - 0.28 11.4 1.8 22 5.3 0.1 3.1 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain O-FucT PF10250.9 EKX45598.1 - 5.1e-05 23.1 0.4 0.00019 21.2 0.4 1.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase NodZ PF05830.11 EKX45598.1 - 0.045 12.6 0.0 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) PDZ_6 PF17820.1 EKX45599.1 - 3.3e-09 36.5 0.3 1.6e-08 34.2 0.1 2.3 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX45599.1 - 3.9e-07 30.3 0.4 9.6e-07 29.1 0.4 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX45599.1 - 5.1e-07 29.9 0.0 1.5e-06 28.4 0.0 1.9 1 0 0 1 1 1 1 PDZ domain Macoilin PF09726.9 EKX45599.1 - 0.00032 19.4 19.0 0.00032 19.4 19.0 3.9 1 1 2 3 3 3 1 Macoilin family Tricorn_PDZ PF14685.6 EKX45599.1 - 0.027 14.4 0.0 0.081 12.9 0.0 1.8 1 0 0 1 1 1 0 Tricorn protease PDZ domain YtxH PF12732.7 EKX45599.1 - 6.3 7.4 0.0 6.3 7.4 0.0 5.7 3 2 0 3 3 3 0 YtxH-like protein DEAD PF00270.29 EKX45601.1 - 8.6e-46 155.9 0.0 1.3e-45 155.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX45601.1 - 1.9e-25 89.4 0.0 1e-22 80.6 0.2 3.1 3 1 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 EKX45601.1 - 4.2e-09 36.6 0.0 8.1e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit EF1_GNE PF00736.19 EKX45602.1 - 0.25 11.5 4.9 13 6.0 4.9 2.2 1 1 0 1 1 1 0 EF-1 guanine nucleotide exchange domain WD40_alt PF14077.6 EKX45602.1 - 2.4 8.1 8.4 15 5.6 1.7 2.9 2 0 0 2 2 2 0 Alternative WD40 repeat motif RWP-RK PF02042.15 EKX45603.1 - 1.1e-15 57.3 0.1 2.2e-15 56.4 0.1 1.5 1 0 0 1 1 1 1 RWP-RK domain DUF4745 PF15923.5 EKX45605.1 - 0.38 10.7 3.7 0.61 10.1 0.6 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4745) Keratin_2_head PF16208.5 EKX45607.1 - 0.64 10.2 14.1 1.3 9.2 14.1 1.4 1 0 0 1 1 1 0 Keratin type II head Cys_Met_Meta_PP PF01053.20 EKX45608.1 - 1e-133 445.6 0.1 2.4e-133 444.4 0.1 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EKX45608.1 - 6.1e-07 28.9 0.1 8.1e-07 28.5 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EKX45608.1 - 5.2e-06 26.0 0.2 7.8e-06 25.4 0.2 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EKX45608.1 - 9.1e-06 25.2 0.2 0.0012 18.3 0.2 2.1 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EKX45608.1 - 0.0005 19.1 0.0 0.0013 17.7 0.1 1.6 2 0 0 2 2 2 1 Aminotransferase class-V SepSecS PF05889.13 EKX45608.1 - 0.098 11.3 0.3 0.15 10.7 0.3 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS NAD_binding_3 PF03447.16 EKX45608.1 - 0.15 12.8 0.2 29 5.3 0.1 2.4 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain AA_permease_2 PF13520.6 EKX45609.1 - 1.9e-33 115.9 45.5 4.6e-33 114.7 45.6 1.5 1 1 1 2 2 2 1 Amino acid permease AA_permease PF00324.21 EKX45609.1 - 3.4e-14 52.3 32.1 3.4e-14 52.3 32.1 2.0 1 1 0 2 2 2 1 Amino acid permease adh_short PF00106.25 EKX45611.1 - 1.6e-35 122.3 0.5 2.9e-33 115.0 0.5 2.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EKX45611.1 - 1.9e-21 76.7 0.9 1.9e-19 70.2 0.9 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX45611.1 - 3.3e-06 27.1 0.0 6.6e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EKX45611.1 - 0.0031 17.0 0.0 0.0049 16.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GcpE PF04551.14 EKX45611.1 - 0.17 11.0 0.1 8.1 5.4 0.0 2.1 2 0 0 2 2 2 0 GcpE protein DAGAT PF03982.13 EKX45613.1 - 0.0012 17.8 0.0 0.0019 17.2 0.0 1.5 1 1 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 EKX45613.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Acyltransferase Lactamase_B_2 PF12706.7 EKX45614.1 - 2e-18 66.7 0.0 2.8e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EKX45614.1 - 2.7e-07 30.8 0.0 5.4e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily STI1 PF17830.1 EKX45615.1 - 1.6e-10 40.7 7.1 3.4e-06 26.9 0.1 2.6 2 0 0 2 2 2 2 STI1 domain Ins_allergen_rp PF06757.13 EKX45615.1 - 0.083 12.8 1.8 0.22 11.5 0.1 2.1 2 0 0 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification KilA-N PF04383.13 EKX45615.1 - 1.9 8.3 6.1 7.4 6.5 6.0 2.0 1 1 0 1 1 1 0 KilA-N domain SMAP PF15477.6 EKX45615.1 - 3.8 8.5 7.6 5.8 7.9 5.9 2.4 1 1 0 1 1 1 0 Small acidic protein family Tetraspanin PF00335.20 EKX45616.1 - 0.0029 17.4 1.0 0.0035 17.1 1.0 1.2 1 0 0 1 1 1 1 Tetraspanin family DTW PF03942.15 EKX45617.1 - 6.9e-23 81.4 0.1 9.2e-23 81.0 0.1 1.2 1 0 0 1 1 1 1 DTW domain DUF1350 PF07082.11 EKX45618.1 - 2e-42 145.2 0.0 2.4e-41 141.7 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1350) DHH PF01368.20 EKX45619.1 - 1.8e-11 44.2 0.0 3.1e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 DHH family DHHA2 PF02833.14 EKX45619.1 - 2.2e-08 34.4 0.5 3.7e-08 33.7 0.5 1.3 1 0 0 1 1 1 1 DHHA2 domain Lactamase_B_5 PF14597.6 EKX45619.1 - 0.044 13.3 0.2 0.09 12.3 0.2 1.5 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily MRP-S28 PF10213.9 EKX45620.1 - 5.7e-11 42.9 0.0 8.5e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF2730 PF10805.8 EKX45621.1 - 0.1 12.7 2.1 1.8 8.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) PX PF00787.24 EKX45622.1 - 2.7e-08 33.8 0.5 2.7e-08 33.8 0.5 2.1 3 0 0 3 3 3 1 PX domain PDZ_6 PF17820.1 EKX45622.1 - 8.7e-05 22.3 0.2 0.00023 21.0 0.2 1.7 1 0 0 1 1 1 1 PDZ domain YlzJ PF14035.6 EKX45622.1 - 0.032 14.4 0.1 0.13 12.5 0.0 2.1 2 0 0 2 2 2 0 YlzJ-like protein PDZ_2 PF13180.6 EKX45622.1 - 0.054 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 PDZ domain DUF1043 PF06295.12 EKX45622.1 - 1.3 9.0 5.6 3.3 7.7 5.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) DUF3736 PF12540.8 EKX45622.1 - 4.3 7.5 7.6 3.6 7.7 0.1 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF3736) PDZ PF00595.24 EKX45623.1 - 5.4e-16 58.7 0.1 2.9e-08 33.9 0.0 2.8 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EKX45623.1 - 1.1e-15 57.2 0.1 7.3e-09 35.4 0.0 3.5 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 EKX45623.1 - 2.5e-09 37.3 0.1 0.00056 20.2 0.0 4.2 4 0 0 4 4 4 2 PDZ domain Ctr PF04145.15 EKX45624.1 - 0.036 14.7 0.5 0.24 12.0 0.5 2.3 1 1 0 1 1 1 0 Ctr copper transporter family FXR_C1 PF16096.5 EKX45624.1 - 2.9 8.2 9.8 7.3 6.9 9.8 1.6 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 DUF2115 PF09888.9 EKX45624.1 - 4.7 7.7 5.9 5.3 7.5 1.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) EF-hand_1 PF00036.32 EKX45625.1 - 6.3e-11 41.0 0.0 0.00033 20.0 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX45625.1 - 6.6e-10 39.3 0.2 1.5e-09 38.1 0.1 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX45625.1 - 4.9e-09 35.4 0.1 0.00017 21.2 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EKX45625.1 - 8.7e-08 31.9 0.2 0.0026 17.5 0.1 3.6 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX45625.1 - 3.8e-06 26.2 0.0 0.056 13.0 0.0 2.4 2 0 0 2 2 2 2 EF hand DAGK_cat PF00781.24 EKX45627.1 - 1.5e-22 79.6 0.0 1.5e-22 79.6 0.0 1.8 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain Zn-ribbon_8 PF09723.10 EKX45627.1 - 7.2 6.8 9.9 0.1 12.8 1.4 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Myb_DNA-binding PF00249.31 EKX45629.1 - 6.8e-33 112.6 2.0 3.8e-18 65.4 0.1 2.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX45629.1 - 5.6e-27 93.8 2.2 6.3e-17 61.6 0.2 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EKX45629.1 - 2.3e-08 33.8 0.1 8.9e-05 22.3 0.0 2.0 1 1 1 2 2 2 2 Myb DNA-binding like Rap1_C PF11626.8 EKX45629.1 - 0.00016 21.7 0.1 0.026 14.6 0.1 2.1 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Claudin_2 PF13903.6 EKX45629.1 - 0.04 13.7 0.0 0.045 13.5 0.0 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction SANT_DAMP1_like PF16282.5 EKX45629.1 - 0.051 13.8 0.1 0.16 12.2 0.0 1.8 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 DUF3511 PF12023.8 EKX45630.1 - 0.054 13.3 0.3 0.16 11.8 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3511) DUF1308 PF07000.11 EKX45630.1 - 0.06 13.3 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) Lipase_3 PF01764.25 EKX45632.1 - 3.6e-10 39.9 0.0 6.6e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EKX45632.1 - 0.0087 16.7 0.1 0.028 15.0 0.1 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family COX4_pro_2 PF07835.12 EKX45632.1 - 0.039 14.1 0.0 0.16 12.1 0.0 2.1 1 0 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV DUF1345 PF07077.11 EKX45632.1 - 0.15 11.7 0.4 0.33 10.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) LMBR1 PF04791.16 EKX45633.1 - 0.011 14.7 1.8 0.012 14.6 1.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FlaC_arch PF05377.11 EKX45633.1 - 0.14 12.5 3.6 6 7.3 0.1 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DAO_C PF16901.5 EKX45633.1 - 0.29 11.0 3.3 12 5.8 0.5 2.5 3 0 0 3 3 3 0 C-terminal domain of alpha-glycerophosphate oxidase Seryl_tRNA_N PF02403.22 EKX45633.1 - 1.1 9.5 8.3 2.8 8.2 7.5 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Swi5 PF07061.11 EKX45633.1 - 8.5 6.5 10.2 3.3 7.9 0.1 3.7 2 1 2 4 4 4 0 Swi5 Atg14 PF10186.9 EKX45633.1 - 9.4 5.2 10.2 16 4.4 10.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Helicase_C PF00271.31 EKX45634.1 - 0.015 15.6 0.0 0.045 14.1 0.0 1.8 1 1 0 1 1 1 0 Helicase conserved C-terminal domain DUF5338 PF17273.2 EKX45634.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5338) Ecm29 PF13001.7 EKX45635.1 - 1.8e-40 139.1 11.6 1.3e-22 80.2 0.0 5.9 4 1 1 5 5 5 3 Proteasome stabiliser HEAT_EZ PF13513.6 EKX45635.1 - 2.8e-07 30.9 6.9 0.72 10.4 0.0 8.4 9 0 0 9 9 9 2 HEAT-like repeat BRX_N PF13713.6 EKX45635.1 - 0.00081 19.1 1.5 0.0075 16.0 0.2 2.7 2 0 0 2 2 2 1 Transcription factor BRX N-terminal domain DNA_pol_B_2 PF03175.13 EKX45635.1 - 0.033 13.1 0.0 0.059 12.2 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral HEAT_2 PF13646.6 EKX45635.1 - 0.041 14.3 5.1 15 6.1 0.1 6.4 7 1 0 7 7 7 0 HEAT repeats HEAT PF02985.22 EKX45635.1 - 0.067 13.5 10.9 35 5.0 0.0 7.8 7 0 0 7 7 7 0 HEAT repeat Sucrose_synth PF00862.19 EKX45635.1 - 0.082 11.2 0.0 0.3 9.3 0.0 1.9 2 0 0 2 2 2 0 Sucrose synthase RabGAP-TBC PF00566.18 EKX45636.1 - 1.4e-21 77.2 1.5 1.6e-21 77.0 1.5 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Macoilin PF09726.9 EKX45637.1 - 0.12 10.9 32.0 0.16 10.5 32.0 1.1 1 0 0 1 1 1 0 Macoilin family LMBR1 PF04791.16 EKX45637.1 - 1.4 7.7 11.6 1.8 7.3 11.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF769 PF05590.11 EKX45637.1 - 1.5 8.2 4.8 0.65 9.4 1.2 1.8 1 1 1 2 2 2 0 Xylella fastidiosa protein of unknown function (DUF769) CDT1 PF08839.11 EKX45638.1 - 1.1e-22 81.2 1.5 8.5e-22 78.3 1.5 2.5 1 1 0 1 1 1 1 DNA replication factor CDT1 like CDT1_C PF16679.5 EKX45638.1 - 0.00012 22.4 6.6 0.00012 22.4 6.6 3.7 2 2 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain DUF4407 PF14362.6 EKX45638.1 - 5.8 6.2 8.5 0.58 9.5 3.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Chlam_PMP PF02415.17 EKX45640.1 - 0.0011 19.3 1.2 0.11 13.0 0.1 2.9 2 0 0 2 2 2 2 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Dehydrin PF00257.19 EKX45640.1 - 2.2 8.8 9.2 0.068 13.7 3.1 1.6 2 0 0 2 2 2 0 Dehydrin Phage_base_V PF04717.12 EKX45642.1 - 0.013 15.4 0.8 0.032 14.1 0.4 1.8 1 1 1 2 2 2 0 Type VI secretion system, phage-baseplate injector Tudor-knot PF11717.8 EKX45642.1 - 0.078 12.9 1.0 0.19 11.6 0.4 2.0 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain Fungal_trans_2 PF11951.8 EKX45644.1 - 0.09 11.6 0.1 0.093 11.5 0.1 1.0 1 0 0 1 1 1 0 Fungal specific transcription factor domain SafA PF17073.5 EKX45644.1 - 0.11 12.4 0.3 0.16 11.9 0.2 1.4 1 1 0 1 1 1 0 Two-component-system connector protein Transglut_core PF01841.19 EKX45645.1 - 0.00036 21.0 0.2 0.013 16.0 0.0 3.3 3 1 0 4 4 4 1 Transglutaminase-like superfamily DUF724 PF05266.14 EKX45645.1 - 0.017 14.9 0.3 0.017 14.9 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) TaqI_C PF12950.7 EKX45645.1 - 0.071 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain zf-RING_7 PF02591.15 EKX45645.1 - 0.082 13.1 0.1 0.23 11.7 0.1 1.8 1 0 0 1 1 1 0 C4-type zinc ribbon domain Rsa3 PF14615.6 EKX45645.1 - 0.085 12.4 1.0 0.21 11.2 1.0 1.6 1 0 0 1 1 1 0 Ribosome-assembly protein 3 DUF5327 PF17261.2 EKX45646.1 - 0.039 14.7 0.4 0.046 14.5 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5327) TMEM247 PF15444.6 EKX45646.1 - 0.041 13.9 0.5 0.041 13.9 0.5 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 FAM195 PF14799.6 EKX45646.1 - 0.07 13.5 0.1 0.088 13.2 0.1 1.3 1 0 0 1 1 1 0 FAM195 family GvpL_GvpF PF06386.11 EKX45646.1 - 0.071 13.0 2.2 0.08 12.9 2.2 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Ribosomal_L28 PF00830.19 EKX45647.1 - 1.7e-22 79.4 0.4 3.3e-22 78.4 0.3 1.5 2 0 0 2 2 2 1 Ribosomal L28 family Cofac_haem_bdg PF04187.13 EKX45648.1 - 6.3e-49 166.9 0.0 1.3e-48 165.9 0.0 1.5 1 0 0 1 1 1 1 Haem-binding uptake, Tiki superfamily, ChaN Bromodomain PF00439.25 EKX45649.1 - 6.9e-18 64.5 0.0 9.6e-18 64.0 0.0 1.2 1 0 0 1 1 1 1 Bromodomain DUF2162 PF09930.9 EKX45650.1 - 0.0069 15.8 1.0 0.029 13.8 1.0 1.9 1 1 0 1 1 1 1 Predicted transporter (DUF2162) TMEM43 PF07787.12 EKX45650.1 - 0.092 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 43 adh_short PF00106.25 EKX45651.1 - 2.5e-37 128.2 0.0 5.5e-36 123.9 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EKX45651.1 - 1.1e-21 77.4 0.0 1.8e-20 73.5 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX45651.1 - 3.2e-07 30.4 0.1 5e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EKX45651.1 - 0.0006 19.3 0.0 0.001 18.6 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EKX45651.1 - 0.042 12.9 0.0 0.093 11.8 0.0 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain DUF3453 PF11935.8 EKX45654.1 - 2e-15 57.1 2.5 5.6e-15 55.6 0.2 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3453) API5 PF05918.11 EKX45654.1 - 0.013 14.4 0.2 0.76 8.5 0.0 2.7 2 1 1 3 3 3 0 Apoptosis inhibitory protein 5 (API5) P19Arf_N PF07392.12 EKX45654.1 - 0.031 14.7 0.3 0.21 12.0 0.0 2.6 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus HEAT PF02985.22 EKX45654.1 - 0.12 12.7 9.4 3.2 8.3 0.0 6.0 6 0 0 6 6 6 0 HEAT repeat Opiods_neuropep PF01160.18 EKX45654.1 - 4.6 7.4 5.7 5.9 7.1 0.2 2.9 3 0 0 3 3 3 0 Vertebrate endogenous opioids neuropeptide Symplekin_C PF12295.8 EKX45655.1 - 6.5e-23 81.8 1.5 7.2e-17 62.1 0.8 2.5 1 1 1 2 2 2 2 Symplekin tight junction protein C terminal MFS_2 PF13347.6 EKX45657.1 - 2.2e-11 43.0 18.5 1.1e-10 40.6 15.0 2.8 1 1 1 2 2 2 1 MFS/sugar transport protein DUF2985 PF11204.8 EKX45657.1 - 4.3 7.6 6.5 1.3 9.2 0.1 3.3 4 1 0 4 4 4 0 Protein of unknown function (DUF2985) TCR PF03638.15 EKX45658.1 - 2e-21 76.0 47.9 1.5e-10 41.2 19.5 2.2 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 EKX45658.1 - 0.89 9.7 48.0 0.13 12.4 19.9 2.8 2 1 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 HOOK PF05622.12 EKX45659.1 - 0.035 12.3 0.2 0.044 12.0 0.2 1.0 1 0 0 1 1 1 0 HOOK protein Thioredoxin_7 PF13899.6 EKX45660.1 - 4.2e-12 46.1 0.0 6.9e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 EKX45660.1 - 1.1e-06 28.5 0.0 1.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EKX45660.1 - 0.0013 19.2 0.0 0.0027 18.1 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Glutaredoxin PF00462.24 EKX45660.1 - 0.0014 18.8 0.0 0.003 17.7 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Thioredox_DsbH PF03190.15 EKX45660.1 - 0.04 13.9 0.0 0.045 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Thioredoxin_9 PF14595.6 EKX45660.1 - 0.064 13.0 0.0 0.14 11.9 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin HTH_psq PF05225.16 EKX45660.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 helix-turn-helix, Psq domain UCH_1 PF13423.6 EKX45660.1 - 0.14 11.7 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase TPR_17 PF13431.6 EKX45661.1 - 6.3e-07 29.4 0.2 0.013 15.9 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX45661.1 - 9.6e-07 28.5 6.1 0.00034 20.5 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX45661.1 - 4.5e-06 26.8 5.0 0.045 14.0 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX45661.1 - 4.7e-06 26.2 4.7 0.0057 16.6 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX45661.1 - 1.8e-05 24.3 2.9 0.00033 20.3 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX45661.1 - 3.2e-05 24.5 5.1 0.0026 18.4 0.7 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX45661.1 - 4.1e-05 23.5 2.8 0.62 10.4 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX45661.1 - 5.8e-05 23.5 3.5 0.075 13.6 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX45661.1 - 0.00034 21.2 6.8 0.018 15.8 0.3 3.8 1 1 3 4 4 4 1 Tetratricopeptide repeat Coatomer_E PF04733.14 EKX45661.1 - 0.00074 19.0 0.4 0.0015 18.0 0.2 1.6 1 1 1 2 2 2 1 Coatomer epsilon subunit TPR_9 PF13371.6 EKX45661.1 - 0.0024 18.0 0.3 0.057 13.6 0.0 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX45661.1 - 0.0043 16.7 0.1 0.17 11.6 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_6 PF13174.6 EKX45661.1 - 0.091 13.4 0.8 13 6.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPPII_N PF12583.8 EKX45661.1 - 0.12 12.9 1.3 1.8 9.1 0.1 2.3 1 1 1 2 2 2 0 Tripeptidyl peptidase II N terminal TPR_10 PF13374.6 EKX45661.1 - 0.36 10.8 0.2 0.36 10.8 0.2 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Acyl-CoA_dh_1 PF00441.24 EKX45662.1 - 2.3e-47 160.9 4.1 3.8e-47 160.3 4.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EKX45662.1 - 8e-35 119.9 0.0 1.8e-34 118.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EKX45662.1 - 1.9e-27 95.3 0.1 4.3e-27 94.2 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EKX45662.1 - 2.4e-21 76.4 2.5 3.4e-21 75.9 2.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EKX45662.1 - 0.096 12.3 0.2 0.34 10.5 0.0 1.9 2 0 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Phage_TTP_11 PF16460.5 EKX45662.1 - 0.13 12.1 0.1 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 Phage tail tube, TTP, lambda-like TYW3 PF02676.14 EKX45663.1 - 5.8e-49 166.4 0.0 9.2e-49 165.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase TYW3 Met_10 PF02475.16 EKX45664.1 - 8e-26 91.0 0.0 1.2e-25 90.4 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 EKX45664.1 - 3.3e-05 23.5 0.0 0.00022 20.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain tRNA_U5-meth_tr PF05958.11 EKX45664.1 - 0.00047 19.3 0.0 0.00061 18.9 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_18 PF12847.7 EKX45664.1 - 0.001 19.0 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX45664.1 - 0.0025 18.5 0.0 0.0056 17.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 EKX45664.1 - 0.059 12.4 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Herpes_capsid PF06112.11 EKX45666.1 - 0.39 10.8 4.7 0.57 10.2 4.7 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Vps4_C PF09336.10 EKX45667.1 - 0.14 12.2 0.8 21 5.2 0.1 2.3 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain DUF1580 PF07618.11 EKX45667.1 - 0.39 10.4 1.8 32 4.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1580) RVT_1 PF00078.27 EKX45668.1 - 4.9e-08 32.8 0.0 1.7e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DEC-1_N PF04625.13 EKX45668.1 - 0.015 14.3 0.6 0.03 13.4 0.6 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region ORC5_C PF14630.6 EKX45668.1 - 0.022 14.3 0.1 0.038 13.5 0.1 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus FKBP_C PF00254.28 EKX45669.1 - 0.00052 20.3 0.1 0.0014 19.0 0.1 1.9 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Peptidase_S9_N PF02897.15 EKX45671.1 - 2.6e-100 336.1 2.3 3.5e-100 335.7 2.3 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 EKX45671.1 - 2.1e-63 213.6 0.0 5e-63 212.4 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 EKX45671.1 - 0.039 12.6 0.0 0.066 11.9 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) TMEM154 PF15102.6 EKX45672.1 - 0.13 12.2 11.2 0.23 11.4 11.2 1.5 1 0 0 1 1 1 0 TMEM154 protein family Stevor PF17410.2 EKX45672.1 - 0.14 11.6 7.8 0.18 11.3 7.8 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Golgin_A5 PF09787.9 EKX45673.1 - 0.18 11.3 18.6 0.22 11.0 18.6 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 TBCC_N PF16752.5 EKX45673.1 - 0.35 11.3 11.7 0.6 10.6 7.9 2.1 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Acyltransferase PF01553.21 EKX45674.1 - 1.7e-09 37.4 0.0 7.4e-05 22.4 0.0 2.5 2 0 0 2 2 2 2 Acyltransferase Ribosomal_L7Ae PF01248.26 EKX45675.1 - 6.3e-26 89.9 0.0 7.1e-26 89.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Sulfotransfer_2 PF03567.14 EKX45676.1 - 4.6e-08 33.3 0.8 9.2e-08 32.3 0.8 1.5 1 1 0 1 1 1 1 Sulfotransferase family Asp PF00026.23 EKX45677.1 - 6e-15 55.5 0.0 9.6e-07 28.5 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EKX45677.1 - 0.00021 21.6 0.0 0.00029 21.1 0.0 1.2 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Swi3 PF07962.12 EKX45678.1 - 7.2e-22 77.2 0.2 2.1e-21 75.7 0.0 1.8 2 0 0 2 2 2 1 Replication Fork Protection Component Swi3 DUF676 PF05057.14 EKX45679.1 - 0.00045 19.8 0.0 0.00063 19.3 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) RNase_HII PF01351.18 EKX45680.1 - 2.3e-40 138.6 0.1 2.6e-40 138.4 0.1 1.0 1 0 0 1 1 1 1 Ribonuclease HII CagY_M PF07337.11 EKX45680.1 - 0.07 12.8 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 DC-EC Repeat AAA_11 PF13086.6 EKX45680.1 - 0.07 12.9 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 EKX45684.1 - 3e-25 88.0 22.9 2.3e-05 25.1 0.9 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.8 EKX45684.1 - 2.1e-06 26.7 1.5 0.034 12.8 0.1 3.8 4 1 0 4 4 4 3 Nucleoporin Nup120/160 PQQ_3 PF13570.6 EKX45684.1 - 9.2e-05 22.8 0.2 0.71 10.4 0.0 4.0 5 0 0 5 5 5 2 PQQ-like domain Nucleoporin_N PF08801.11 EKX45684.1 - 0.00062 18.6 0.0 0.44 9.2 0.0 3.4 3 1 0 4 4 4 2 Nup133 N terminal like Glyco_hydro_31 PF01055.26 EKX45685.1 - 7.2e-138 460.5 0.4 9.3e-138 460.1 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EKX45685.1 - 3.1e-15 56.2 0.1 1.1e-14 54.4 0.1 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 EKX45685.1 - 0.0062 16.8 0.1 0.017 15.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) MepB PF08877.10 EKX45685.1 - 0.19 11.4 0.0 0.46 10.2 0.0 1.5 1 0 0 1 1 1 0 MepB protein TTL PF03133.15 EKX45686.1 - 1.4e-67 227.9 0.0 1.7e-67 227.6 0.0 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EKX45686.1 - 5.1e-09 35.7 0.3 0.00031 20.1 0.0 3.2 2 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EKX45686.1 - 7.6e-06 25.4 0.0 0.013 14.7 0.0 2.4 2 1 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EKX45686.1 - 0.0089 16.1 0.0 0.024 14.7 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 EKX45686.1 - 0.077 12.6 0.0 2.5 7.6 0.0 2.1 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Acyltransferase PF01553.21 EKX45687.1 - 7.2e-05 22.4 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase MIP PF00230.20 EKX45688.1 - 0.0032 17.2 4.2 0.0047 16.7 4.2 1.3 1 0 0 1 1 1 1 Major intrinsic protein DUF5554 PF17709.1 EKX45688.1 - 0.14 12.3 0.9 0.53 10.4 0.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5554) HECT PF00632.25 EKX45689.1 - 5.1e-61 206.8 0.0 6.1e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) TMF_TATA_bd PF12325.8 EKX45690.1 - 7.3e-07 29.4 10.2 3.3e-05 24.1 6.1 2.1 1 1 1 2 2 2 2 TATA element modulatory factor 1 TATA binding Cast PF10174.9 EKX45690.1 - 0.00016 20.1 6.6 0.00059 18.2 7.0 1.6 1 1 1 2 2 2 1 RIM-binding protein of the cytomatrix active zone DUF2353 PF09789.9 EKX45690.1 - 0.011 15.2 8.0 0.014 14.8 8.0 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DUF1664 PF07889.12 EKX45690.1 - 0.024 14.7 1.2 0.053 13.6 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 EKX45690.1 - 0.075 13.3 6.3 0.11 12.7 4.3 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4201 PF13870.6 EKX45690.1 - 0.23 11.2 7.2 0.071 12.8 1.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) APG6_N PF17675.1 EKX45690.1 - 0.46 11.0 7.5 0.47 11.0 6.3 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region FUSC PF04632.12 EKX45690.1 - 0.51 8.8 1.8 0.63 8.5 1.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMF_DNA_bd PF12329.8 EKX45690.1 - 1.1 9.3 5.9 0.47 10.5 1.0 2.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.10 EKX45690.1 - 1.4 9.1 7.6 5.2 7.3 7.6 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Cep57_CLD_2 PF14197.6 EKX45690.1 - 1.7 8.8 9.1 1.9 8.7 0.5 2.9 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Rootletin PF15035.6 EKX45690.1 - 2.4 8.1 13.5 4 7.4 0.5 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion EF-hand_6 PF13405.6 EKX45691.1 - 3.6e-12 45.2 2.1 8.3e-05 22.2 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EKX45691.1 - 3.9e-12 44.8 3.4 6.8e-06 25.3 0.8 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX45691.1 - 3.7e-10 40.1 0.2 9e-10 38.9 0.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX45691.1 - 2.6e-08 33.0 4.3 5.8e-05 22.4 0.8 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX45691.1 - 0.00033 20.4 1.1 0.012 15.5 0.7 2.3 1 1 1 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX45691.1 - 0.1 12.9 0.7 0.19 12.1 0.0 1.8 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region BAG PF02179.16 EKX45692.1 - 1.6e-07 31.6 5.1 1.7e-05 25.2 4.0 2.6 2 0 0 2 2 2 1 BAG domain TPR_12 PF13424.6 EKX45692.1 - 2.1e-06 27.9 6.4 0.0014 18.9 0.5 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX45692.1 - 9.8e-06 25.3 9.0 0.18 12.0 0.7 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX45692.1 - 2.4e-05 23.9 10.0 0.43 10.5 0.0 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat SPO22 PF08631.10 EKX45692.1 - 0.00027 20.5 2.9 0.00027 20.5 2.9 2.2 2 1 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like Fis1_TPR_C PF14853.6 EKX45692.1 - 0.0003 20.8 1.5 0.00088 19.3 0.1 2.5 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 EKX45692.1 - 0.0013 19.4 16.0 0.79 10.7 0.0 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX45692.1 - 0.013 15.9 0.2 0.18 12.3 0.0 4.0 4 1 2 6 6 5 0 Tetratricopeptide repeat NapD PF03927.13 EKX45692.1 - 0.022 14.8 0.0 0.35 11.0 0.0 2.9 3 1 1 4 4 4 0 NapD protein TPR_9 PF13371.6 EKX45692.1 - 0.025 14.7 3.4 0.14 12.3 0.7 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF5082 PF16888.5 EKX45692.1 - 0.036 14.3 0.8 0.085 13.1 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) PerC PF06069.11 EKX45692.1 - 0.074 13.3 1.7 0.21 11.9 0.2 2.3 1 1 1 2 2 2 0 PerC transcriptional activator TPR_8 PF13181.6 EKX45692.1 - 0.1 12.8 1.9 88 3.7 0.1 4.2 4 1 0 4 4 3 0 Tetratricopeptide repeat MAS20 PF02064.15 EKX45692.1 - 0.71 10.0 5.0 1.4 9.0 0.0 3.0 3 1 0 3 3 3 0 MAS20 protein import receptor TPR_7 PF13176.6 EKX45692.1 - 1.3 9.2 6.5 6.2 7.1 0.2 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EKX45692.1 - 1.4 9.4 3.5 15 6.0 0.4 3.0 2 1 2 4 4 4 0 Alkyl sulfatase dimerisation TPR_16 PF13432.6 EKX45692.1 - 2.8 8.6 11.2 2.9 8.6 0.1 4.2 5 1 1 6 6 4 0 Tetratricopeptide repeat FlgM PF04316.13 EKX45692.1 - 6.1 7.3 6.1 14 6.2 0.1 3.6 4 0 0 4 4 3 0 Anti-sigma-28 factor, FlgM WD40 PF00400.32 EKX45693.1 - 3.1e-11 43.6 7.4 0.00033 21.4 0.5 3.6 2 2 1 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX45693.1 - 1.9e-07 31.3 0.1 0.0026 18.0 0.1 3.3 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Gmad1 PF10647.9 EKX45693.1 - 0.066 13.0 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain AKNA PF12443.8 EKX45693.1 - 0.13 13.0 0.1 0.3 11.8 0.1 1.6 1 0 0 1 1 1 0 AT-hook-containing transcription factor Not3 PF04065.15 EKX45694.1 - 3.4e-82 275.3 19.6 3.4e-82 275.3 19.6 2.2 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EKX45694.1 - 2.3e-38 131.3 1.7 1e-37 129.1 1.7 2.2 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2748 PF10871.8 EKX45694.1 - 0.018 13.7 1.6 0.038 12.6 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2748) YppG PF14179.6 EKX45694.1 - 4.3 8.1 7.6 16 6.2 7.6 2.0 1 0 0 1 1 1 0 YppG-like protein Ank_5 PF13857.6 EKX45695.1 - 0.029 14.7 0.0 0.53 10.7 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) SET PF00856.28 EKX45696.1 - 0.21 12.0 0.0 0.27 11.6 0.0 1.3 1 0 0 1 1 1 0 SET domain Vma12 PF11712.8 EKX45697.1 - 6 6.9 7.0 2.8 8.0 1.5 2.4 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase EF-hand_7 PF13499.6 EKX45698.1 - 7.9e-20 71.1 8.9 1.2e-14 54.5 2.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX45698.1 - 2.5e-18 64.2 10.1 3.3e-07 29.4 0.6 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EKX45698.1 - 1.1e-13 49.9 6.7 4.3e-07 29.3 0.3 4.5 4 2 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EKX45698.1 - 1.1e-10 41.2 9.5 0.00018 21.3 1.2 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 EKX45698.1 - 1.3e-06 28.6 0.1 0.00032 20.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EKX45698.1 - 2.5e-06 26.7 0.9 2.5e-06 26.7 0.9 3.6 3 1 1 4 4 4 1 EF hand DUF89 PF01937.19 EKX45698.1 - 0.049 12.6 0.5 0.078 11.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF89 Xan_ur_permease PF00860.20 EKX45699.1 - 7.9e-26 90.7 22.4 2.1e-16 59.6 3.3 3.0 2 1 0 2 2 2 2 Permease family DUF4834 PF16118.5 EKX45699.1 - 0.00082 20.3 1.2 0.23 12.4 0.5 3.3 3 0 0 3 3 2 1 Domain of unknown function (DUF4834) SpoIIIAH PF12685.7 EKX45699.1 - 0.0034 17.2 9.0 0.028 14.3 3.6 2.3 2 0 0 2 2 2 1 SpoIIIAH-like protein RNA_pol_Rpc4 PF05132.14 EKX45699.1 - 0.055 13.9 12.1 0.43 11.0 7.6 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 SID-1_RNA_chan PF13965.6 EKX45699.1 - 0.11 10.9 0.2 0.51 8.7 0.3 1.8 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Nodulin_late PF07127.11 EKX45699.1 - 0.19 12.1 0.0 0.61 10.5 0.0 1.9 1 0 0 1 1 1 0 Late nodulin protein DUF719 PF05334.13 EKX45699.1 - 0.23 11.6 12.8 0.39 10.9 7.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF719) DUF913 PF06025.12 EKX45699.1 - 0.24 10.3 11.9 2 7.3 0.1 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) FHIPEP PF00771.20 EKX45699.1 - 0.3 9.5 0.8 2.7 6.3 0.6 2.2 2 0 0 2 2 2 0 FHIPEP family TRAP_alpha PF03896.16 EKX45699.1 - 0.32 10.2 23.4 0.52 9.5 4.2 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Eapp_C PF10238.9 EKX45699.1 - 0.37 10.9 17.7 5.1 7.2 15.4 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein Connexin PF00029.19 EKX45699.1 - 0.4 10.4 12.0 23 4.6 11.3 2.3 2 0 0 2 2 2 0 Connexin Myc_N PF01056.18 EKX45699.1 - 0.62 9.9 18.6 0.18 11.6 1.1 2.3 2 0 0 2 2 2 0 Myc amino-terminal region FAM176 PF14851.6 EKX45699.1 - 1.5 8.5 24.1 0.13 11.9 0.5 2.6 2 0 0 2 2 2 0 FAM176 family Tim54 PF11711.8 EKX45699.1 - 1.9 7.2 21.3 0.89 8.3 0.1 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF2052 PF09747.9 EKX45699.1 - 2.9 8.0 36.9 5.4 7.1 22.9 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Peptidase_S49_N PF08496.10 EKX45699.1 - 3.2 7.8 11.9 67 3.5 10.6 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal CPSF100_C PF13299.6 EKX45699.1 - 5.7 7.1 17.9 19 5.4 11.7 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Coilin_N PF15862.5 EKX45699.1 - 6.5 6.5 21.9 1.5 8.6 13.4 2.6 2 0 0 2 2 2 0 Coilin N-terminus Presenilin PF01080.17 EKX45699.1 - 7.6 5.2 16.7 7.8 5.1 13.1 2.1 2 0 0 2 2 2 0 Presenilin Neur_chan_memb PF02932.16 EKX45699.1 - 8 6.4 5.9 26 4.8 5.1 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Peroxin-13_N PF04088.13 EKX45699.1 - 8.7 6.6 9.6 10 6.4 0.0 3.1 3 0 0 3 3 3 0 Peroxin 13, N-terminal region V_ATPase_I PF01496.19 EKX45699.1 - 8.9 4.1 15.4 5.8 4.7 10.4 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF3938 PF13074.6 EKX45700.1 - 4.9 7.5 6.5 17 5.7 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3938) Cupin_8 PF13621.6 EKX45703.1 - 7.5e-09 35.7 0.0 1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EKX45703.1 - 1.6e-05 25.3 0.0 3.4e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 JmjC domain, hydroxylase TPR_8 PF13181.6 EKX45703.1 - 0.061 13.6 0.0 0.19 12.0 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat GAF_3 PF13492.6 EKX45705.1 - 1.3e-08 35.2 1.1 0.068 13.5 0.0 4.3 3 1 0 4 4 4 3 GAF domain GAF_2 PF13185.6 EKX45705.1 - 8.6e-05 22.9 0.0 5.9 7.2 0.0 4.1 3 1 0 3 3 3 2 GAF domain GAF PF01590.26 EKX45705.1 - 0.0018 18.9 0.0 1.3 9.6 0.0 4.1 3 2 0 3 3 3 1 GAF domain ISG65-75 PF11727.8 EKX45705.1 - 0.0076 15.5 7.7 0.014 14.7 7.7 1.4 1 0 0 1 1 1 1 Invariant surface glycoprotein Dpy-30 PF05186.13 EKX45705.1 - 0.0083 15.8 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 1 Dpy-30 motif DUF4778 PF16008.5 EKX45705.1 - 1.2 9.1 7.6 2.4 8.2 7.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Mod_r PF07200.13 EKX45705.1 - 3.3 7.8 19.0 6.1 6.9 14.9 2.6 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein UPF0242 PF06785.11 EKX45705.1 - 4.7 7.3 11.9 12 5.9 11.9 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ARGLU PF15346.6 EKX45705.1 - 4.7 7.1 32.8 0.36 10.7 25.9 2.4 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 S4 PF01479.25 EKX45707.1 - 9.9e-13 47.6 0.0 3.6e-12 45.8 0.0 1.9 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 EKX45707.1 - 8.1e-08 33.1 1.6 1.2e-07 32.6 1.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain SpmSyn_N PF17950.1 EKX45707.1 - 0.057 13.6 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 S-adenosylmethionine decarboxylase N -terminal CHD5 PF04420.14 EKX45707.1 - 0.08 12.8 2.5 0.25 11.2 1.0 2.1 2 0 0 2 2 2 0 CHD5-like protein Acylphosphatase PF00708.18 EKX45708.1 - 1.9e-23 82.7 0.1 2.3e-23 82.4 0.1 1.1 1 0 0 1 1 1 1 Acylphosphatase HlyD_D4 PF16572.5 EKX45708.1 - 0.068 13.0 0.0 0.088 12.7 0.0 1.2 1 0 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB DUF2871 PF11070.8 EKX45708.1 - 0.12 12.6 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2871) NAF PF03822.14 EKX45709.1 - 1.6 9.0 6.1 16 5.8 2.5 3.0 2 1 0 2 2 2 0 NAF domain C2 PF00168.30 EKX45710.1 - 4.2e-07 30.2 0.0 1e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 C2 domain O-FucT PF10250.9 EKX45710.1 - 3.6e-05 23.6 0.0 0.00012 21.9 0.0 1.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase AAA_18 PF13238.6 EKX45710.1 - 0.012 16.1 3.3 0.014 15.9 0.1 2.8 3 0 0 3 3 2 0 AAA domain ATPase_2 PF01637.18 EKX45710.1 - 0.013 15.5 0.2 0.056 13.3 0.0 2.1 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 EKX45710.1 - 0.018 15.5 0.0 0.079 13.3 0.0 2.2 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EKX45710.1 - 0.02 15.3 0.1 0.075 13.5 0.1 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EKX45710.1 - 0.02 14.8 0.0 0.048 13.6 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain F5_F8_type_C PF00754.25 EKX45710.1 - 0.031 14.4 0.0 0.21 11.7 0.0 2.2 1 1 0 1 1 1 0 F5/8 type C domain NACHT PF05729.12 EKX45710.1 - 0.051 13.5 0.2 2.1 8.3 0.0 3.4 3 0 0 3 3 3 0 NACHT domain AAA_28 PF13521.6 EKX45710.1 - 0.052 13.8 1.4 0.34 11.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EKX45710.1 - 0.056 13.8 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 EKX45710.1 - 0.063 13.5 1.0 0.39 11.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 EKX45710.1 - 0.1 12.6 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 EKX45710.1 - 0.11 12.4 0.9 11 6.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.14 EKX45710.1 - 0.29 10.3 1.7 0.36 10.0 0.1 2.0 2 0 0 2 2 2 0 KAP family P-loop domain efb-c PF12199.8 EKX45710.1 - 0.48 10.5 2.4 1.1 9.4 0.3 2.4 2 0 0 2 2 2 0 Extracellular fibrinogen binding protein C terminal Laminin_EGF PF00053.24 EKX45710.1 - 3.6 7.8 5.5 9.5 6.4 5.5 1.7 1 0 0 1 1 1 0 Laminin EGF domain CENP-F_leu_zip PF10473.9 EKX45711.1 - 3.8e-05 23.7 10.0 3.8e-05 23.7 10.0 2.6 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FPP PF05911.11 EKX45711.1 - 0.005 15.1 10.6 0.0076 14.5 10.6 1.2 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil BCAS2 PF05700.11 EKX45711.1 - 0.016 14.9 8.4 0.032 13.9 8.4 1.5 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) PV-1 PF06637.11 EKX45711.1 - 0.043 12.6 15.7 0.07 11.9 15.7 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) MIP-T3_C PF17749.1 EKX45711.1 - 0.07 13.1 12.2 0.12 12.3 10.3 2.3 2 1 1 3 3 2 0 Microtubule-binding protein MIP-T3 C-terminal region CALCOCO1 PF07888.11 EKX45711.1 - 0.072 11.9 20.3 0.16 10.8 20.3 1.6 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3496 PF12001.8 EKX45711.1 - 0.16 12.3 8.1 0.51 10.7 8.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) FH2 PF02181.23 EKX45711.1 - 0.24 10.5 5.1 0.54 9.3 5.1 1.6 1 0 0 1 1 1 0 Formin Homology 2 Domain AAA_13 PF13166.6 EKX45711.1 - 0.41 9.2 6.1 0.83 8.2 6.1 1.4 1 0 0 1 1 1 0 AAA domain Laminin_I PF06008.14 EKX45711.1 - 0.41 10.3 15.7 0.59 9.8 0.2 2.9 2 1 0 2 2 2 0 Laminin Domain I Golgin_A5 PF09787.9 EKX45711.1 - 0.6 9.5 18.3 0.39 10.1 8.4 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 SOGA PF11365.8 EKX45711.1 - 0.61 11.3 18.3 1.5 10.0 12.7 3.3 1 1 2 3 3 3 0 Protein SOGA CENP-Q PF13094.6 EKX45711.1 - 0.62 10.3 20.7 0.13 12.4 4.0 2.7 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF724 PF05266.14 EKX45711.1 - 0.94 9.3 10.4 3.4 7.5 10.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Macoilin PF09726.9 EKX45711.1 - 0.98 7.9 20.7 0.0056 15.3 9.9 2.0 2 0 0 2 2 2 0 Macoilin family Cnn_1N PF07989.11 EKX45711.1 - 1.1 9.4 16.2 8.7 6.6 2.0 3.8 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 IFT57 PF10498.9 EKX45711.1 - 1.3 7.9 11.9 3.6 6.5 11.9 1.6 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Leu_zip PF15294.6 EKX45711.1 - 1.6 8.2 14.1 4 6.9 13.9 1.8 1 1 0 1 1 1 0 Leucine zipper GAS PF13851.6 EKX45711.1 - 1.6 8.0 21.5 1.7 7.9 9.3 2.6 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 EKX45711.1 - 1.6 7.7 14.7 4 6.4 14.7 1.7 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FapA PF03961.13 EKX45711.1 - 1.7 7.2 8.0 2.6 6.6 8.0 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A PRKG1_interact PF15898.5 EKX45711.1 - 1.9 9.4 20.0 2.2 9.2 13.3 3.7 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain UPF0242 PF06785.11 EKX45711.1 - 2 8.5 17.1 11 6.1 16.9 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus bZIP_Maf PF03131.17 EKX45711.1 - 2.1 8.9 17.3 2.7 8.6 4.4 3.4 2 1 0 2 2 2 0 bZIP Maf transcription factor KASH_CCD PF14662.6 EKX45711.1 - 3.2 7.5 19.2 8.3 6.2 18.8 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH FlaC_arch PF05377.11 EKX45711.1 - 3.4 8.1 10.3 5.5 7.5 0.2 3.7 4 2 0 4 4 3 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.12 EKX45711.1 - 3.9 7.5 28.1 0.15 12.1 1.1 3.7 4 1 0 4 4 3 0 TPR/MLP1/MLP2-like protein Rootletin PF15035.6 EKX45711.1 - 4 7.4 21.7 40 4.2 16.8 3.3 2 2 2 4 4 4 0 Ciliary rootlet component, centrosome cohesion DUF2968 PF11180.8 EKX45711.1 - 6.2 6.4 22.8 0.24 11.0 7.8 2.6 2 1 1 3 3 2 0 Protein of unknown function (DUF2968) MutS_IV PF05190.18 EKX45711.1 - 6.4 7.2 9.2 3.7 8.0 2.5 3.6 1 1 2 3 3 3 0 MutS family domain IV YabA PF06156.13 EKX45711.1 - 6.6 7.4 11.8 1.8 9.2 4.3 2.8 1 1 1 2 2 2 0 Initiation control protein YabA Spc7 PF08317.11 EKX45711.1 - 6.6 5.5 22.4 3.7 6.3 19.4 2.0 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF4094 PF13334.6 EKX45711.1 - 7.3 7.1 8.0 48 4.5 0.3 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) DUF1640 PF07798.11 EKX45711.1 - 9.2 6.3 18.7 18 5.3 9.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Lactamase_B_2 PF12706.7 EKX45712.1 - 2.1e-07 30.6 0.1 2.8e-07 30.3 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EKX45712.1 - 0.00016 21.8 0.2 0.057 13.4 0.0 2.1 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Exo_endo_phos PF03372.23 EKX45714.1 - 1.9e-07 30.9 0.0 3.5e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Nitroreductase PF00881.24 EKX45714.1 - 0.71 9.9 3.2 6.3 6.8 0.2 2.4 2 0 0 2 2 2 0 Nitroreductase family AA_permease_2 PF13520.6 EKX45715.1 - 5e-34 117.8 34.5 7e-34 117.4 34.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EKX45715.1 - 6.3e-19 67.9 27.0 1.4e-18 66.7 27.0 1.6 1 1 0 1 1 1 1 Amino acid permease RCC1 PF00415.18 EKX45717.1 - 3.4e-55 184.5 21.7 7.7e-12 45.6 0.3 6.2 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX45717.1 - 1.8e-26 91.3 28.8 3.2e-06 26.8 0.1 6.3 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat DUF3696 PF12476.8 EKX45717.1 - 0.2 12.1 0.0 0.69 10.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3696) DUF866 PF05907.13 EKX45718.1 - 6.9e-40 136.5 0.0 7.7e-40 136.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) RNHCP PF12647.7 EKX45718.1 - 0.0039 17.1 0.3 0.99 9.4 0.0 2.4 1 1 1 2 2 2 2 RNHCP domain Zn-ribbon_8 PF09723.10 EKX45718.1 - 0.017 15.2 0.4 0.5 10.5 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Cytochrome_C7 PF14522.6 EKX45718.1 - 0.024 14.6 0.7 0.059 13.4 0.7 1.7 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c Cytochrom_c3_2 PF14537.6 EKX45718.1 - 0.028 14.9 0.1 0.047 14.1 0.1 1.4 1 0 0 1 1 1 0 Cytochrome c3 Ribosomal_S27e PF01667.17 EKX45718.1 - 0.032 13.9 0.8 1.6 8.5 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S27 Ribosomal_L44 PF00935.19 EKX45718.1 - 0.038 14.5 0.7 7.8 7.1 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein L44 EF-hand_7 PF13499.6 EKX45719.1 - 0.023 15.2 0.1 0.13 12.7 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain pair Myb_DNA-bind_6 PF13921.6 EKX45720.1 - 2.6e-05 24.4 0.0 6.7e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EKX45720.1 - 7.2e-05 22.9 0.1 0.00016 21.8 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Thioredoxin_8 PF13905.6 EKX45721.1 - 1.5e-21 76.5 0.0 2.4e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 EKX45721.1 - 2.5e-09 37.0 0.0 4e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EKX45721.1 - 2.3e-05 24.3 0.0 3.3e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 EKX45721.1 - 0.0017 18.3 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin CobW_C PF07683.14 EKX45721.1 - 0.13 12.2 0.0 0.6 10.1 0.0 2.0 2 0 0 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain Ribul_P_3_epim PF00834.19 EKX45722.1 - 6.6e-65 218.2 0.1 7.7e-65 218.0 0.1 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 EKX45722.1 - 0.0061 16.4 0.1 0.021 14.6 0.0 2.0 2 1 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain OMPdecase PF00215.24 EKX45722.1 - 0.017 14.7 0.1 0.033 13.8 0.1 1.7 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family His_biosynth PF00977.21 EKX45722.1 - 0.023 14.2 0.0 0.099 12.1 0.0 1.8 2 0 0 2 2 2 0 Histidine biosynthesis protein TMP-TENI PF02581.17 EKX45722.1 - 0.043 13.1 0.1 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Thiamine monophosphate synthase ThiG PF05690.14 EKX45722.1 - 0.062 12.6 0.1 0.23 10.8 0.1 1.9 1 1 0 1 1 1 0 Thiazole biosynthesis protein ThiG CUE PF02845.16 EKX45722.1 - 0.1 12.3 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 CUE domain FMN_dh PF01070.18 EKX45722.1 - 0.13 11.3 0.1 0.34 9.9 0.0 1.6 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Gly-zipper_Omp PF13488.6 EKX45723.1 - 0.0086 16.1 0.6 0.018 15.0 0.6 1.5 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_YMGG PF13441.6 EKX45723.1 - 0.048 13.4 0.6 0.1 12.3 0.6 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper DUF4134 PF13572.6 EKX45723.1 - 0.53 10.6 0.0 0.53 10.6 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4134) SOG2 PF10428.9 EKX45723.1 - 1.4 8.0 22.1 1.8 7.7 22.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Endomucin PF07010.12 EKX45723.1 - 1.8 8.5 33.8 1.8 8.5 31.9 1.9 2 0 0 2 2 2 0 Endomucin Atrophin-1 PF03154.15 EKX45723.1 - 2.2 6.5 12.3 2.7 6.1 12.3 1.1 1 0 0 1 1 1 0 Atrophin-1 family KAR9 PF08580.10 EKX45723.1 - 3.4 6.1 10.9 4.5 5.7 10.9 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SNARE PF05739.19 EKX45724.1 - 3e-13 49.5 1.2 5.6e-13 48.7 0.1 2.1 2 0 0 2 2 2 1 SNARE domain PSII_Pbs27 PF13326.6 EKX45724.1 - 0.0013 19.1 0.1 0.0042 17.4 0.1 2.0 1 1 0 1 1 1 1 Photosystem II Pbs27 DUF16 PF01519.16 EKX45724.1 - 0.0084 16.6 0.9 0.0084 16.6 0.9 2.7 2 1 1 3 3 3 1 Protein of unknown function DUF16 Baculo_PEP_C PF04513.12 EKX45724.1 - 0.033 14.3 5.4 1.4 8.9 0.5 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cor1 PF04803.12 EKX45724.1 - 0.084 13.1 14.0 0.068 13.4 1.0 3.4 3 1 1 4 4 4 0 Cor1/Xlr/Xmr conserved region Syntaxin PF00804.25 EKX45724.1 - 0.086 12.5 12.1 0.47 10.1 10.0 2.8 1 1 1 2 2 2 0 Syntaxin Syntaxin-6_N PF09177.11 EKX45724.1 - 0.64 10.6 10.9 5.7 7.6 0.1 3.5 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF2316 PF10078.9 EKX45724.1 - 0.71 10.2 5.0 4.2 7.7 0.1 3.1 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2316) Aida_N PF08910.10 EKX45724.1 - 0.95 9.9 5.4 0.52 10.7 0.3 2.7 3 0 0 3 3 3 0 Aida N-terminus DUF1664 PF07889.12 EKX45724.1 - 0.99 9.5 8.4 4.8 7.2 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 EKX45724.1 - 3 8.2 13.2 0.74 10.2 0.5 3.9 3 2 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 COG2 PF06148.11 EKX45724.1 - 4.4 7.4 13.4 0.62 10.2 0.8 3.2 2 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 PCRF PF03462.18 EKX45724.1 - 5.4 6.8 9.2 21 4.9 3.3 2.6 2 1 0 2 2 2 0 PCRF domain Flavoprotein PF02441.19 EKX45725.1 - 2.3e-42 144.4 0.0 2.8e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein TusA PF01206.17 EKX45725.1 - 0.18 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Sulfurtransferase TusA DHDPS PF00701.22 EKX45726.1 - 2.6e-45 154.4 0.0 3e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family ATP_bind_1 PF03029.17 EKX45727.1 - 2.2e-71 240.5 0.0 2.9e-71 240.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 EKX45727.1 - 0.00048 20.3 0.0 0.0015 18.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EKX45727.1 - 0.0012 19.4 0.0 0.0027 18.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EKX45727.1 - 0.004 16.9 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EKX45727.1 - 0.011 15.1 0.0 0.25 10.6 0.0 2.3 3 0 0 3 3 3 0 Zeta toxin MMR_HSR1 PF01926.23 EKX45727.1 - 0.017 15.2 0.0 0.14 12.2 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 EKX45727.1 - 0.018 15.3 0.0 0.065 13.5 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 EKX45727.1 - 0.02 14.6 0.0 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_31 PF13614.6 EKX45727.1 - 0.022 14.7 0.0 2.6 7.9 0.0 2.3 1 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EKX45727.1 - 0.041 14.1 0.1 0.17 12.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 EKX45727.1 - 0.073 12.6 0.5 0.86 9.2 0.5 2.2 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain KTI12 PF08433.10 EKX45727.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_17 PF13207.6 EKX45727.1 - 0.14 12.6 0.1 2.4 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 EKX45727.1 - 0.14 11.9 0.0 0.44 10.3 0.0 1.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_5 PF07728.14 EKX45727.1 - 0.15 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EKX45727.1 - 0.17 12.3 0.0 0.9 10.0 0.0 2.2 3 0 0 3 3 2 0 RNA helicase AAA_16 PF13191.6 EKX45727.1 - 0.19 12.1 0.0 0.44 10.9 0.0 1.7 2 1 0 2 2 2 0 AAA ATPase domain Kelch_1 PF01344.25 EKX45728.1 - 6.2e-37 124.9 16.2 2.2e-10 39.9 0.0 7.1 6 1 0 6 6 6 5 Kelch motif CH PF00307.31 EKX45728.1 - 3e-24 85.3 0.2 9e-15 54.8 0.0 2.5 2 0 0 2 2 2 2 Calponin homology (CH) domain Kelch_6 PF13964.6 EKX45728.1 - 1.4e-16 60.1 5.6 0.00044 20.4 0.0 5.5 5 1 1 6 6 6 4 Kelch motif Kelch_5 PF13854.6 EKX45728.1 - 7.8e-11 41.7 0.7 0.075 13.0 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 EKX45728.1 - 5.5e-08 32.5 2.7 0.0098 15.8 0.1 4.9 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 EKX45728.1 - 3.7e-06 27.1 17.2 0.54 10.6 0.1 7.7 6 2 1 7 7 7 2 Galactose oxidase, central domain CAMSAP_CH PF11971.8 EKX45728.1 - 0.00016 21.4 0.1 0.0034 17.2 0.1 2.7 2 1 0 2 2 2 1 CAMSAP CH domain Kelch_4 PF13418.6 EKX45728.1 - 0.0083 16.1 7.0 0.19 11.8 0.1 4.0 5 0 0 5 5 5 2 Galactose oxidase, central domain EcKinase PF02958.20 EKX45728.1 - 0.086 12.1 2.5 0.15 11.3 2.5 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Tsg PF04668.12 EKX45728.1 - 0.62 10.7 2.1 7.1 7.3 0.3 2.4 1 1 1 2 2 2 0 Twisted gastrulation (Tsg) protein conserved region Sulfotransfer_2 PF03567.14 EKX45729.1 - 1.4e-22 80.8 0.2 1.6e-16 61.0 0.2 2.7 2 1 0 2 2 2 2 Sulfotransferase family zf-NF-X1 PF01422.17 EKX45731.1 - 0.00031 20.7 10.6 0.00031 20.7 10.6 7.6 7 2 0 7 7 7 4 NF-X1 type zinc finger F420_oxidored PF03807.17 EKX45733.1 - 4.5e-13 49.6 0.0 1.3e-11 44.9 0.0 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent P5CR_dimer PF14748.6 EKX45733.1 - 3.5e-07 30.4 0.0 8.5e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation TFCD_C PF12612.8 EKX45733.1 - 0.014 15.2 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal OCD_Mu_crystall PF02423.15 EKX45733.1 - 0.015 14.3 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family 2-Hacid_dh_C PF02826.19 EKX45733.1 - 0.061 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Hist_deacetyl PF00850.19 EKX45735.1 - 2e-45 155.6 0.0 3.4e-45 154.8 0.0 1.3 1 1 0 1 1 1 1 Histone deacetylase domain B12-binding PF02310.19 EKX45735.1 - 0.0038 17.3 0.0 0.018 15.1 0.0 2.1 1 1 1 2 2 2 1 B12 binding domain C1_2 PF03107.16 EKX45736.1 - 3.7e-07 30.3 24.4 0.0005 20.3 5.1 3.5 3 0 0 3 3 3 2 C1 domain ZZ PF00569.17 EKX45736.1 - 0.0051 16.6 20.0 0.03 14.1 3.2 3.6 3 0 0 3 3 3 2 Zinc finger, ZZ type GvpG PF05120.12 EKX45736.1 - 0.078 13.0 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Gas vesicle protein G SHOCT PF09851.9 EKX45736.1 - 0.36 10.6 2.3 0.65 9.8 2.3 1.4 1 0 0 1 1 1 0 Short C-terminal domain zf-BED PF02892.15 EKX45736.1 - 0.55 10.3 7.1 0.23 11.5 0.5 3.1 2 0 0 2 2 2 0 BED zinc finger FOXP-CC PF16159.5 EKX45736.1 - 1.4 9.6 5.7 1.6 9.4 0.5 2.7 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-UBR PF02207.20 EKX45736.1 - 2.1 8.6 21.6 5.3 7.3 5.6 3.7 2 1 2 4 4 4 0 Putative zinc finger in N-recognin (UBR box) Fe_hyd_lg_C PF02906.14 EKX45737.1 - 2e-49 168.5 0.0 2.8e-49 168.0 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain HMA PF00403.26 EKX45737.1 - 0.25 11.8 2.2 0.22 12.0 0.6 1.8 2 0 0 2 2 2 0 Heavy-metal-associated domain SpoU_methylase PF00588.19 EKX45738.1 - 2.2e-30 105.7 0.0 1e-29 103.5 0.0 1.8 1 1 0 1 1 1 1 SpoU rRNA Methylase family DUF3427 PF11907.8 EKX45738.1 - 0.017 14.4 0.0 0.022 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3427) Sel1 PF08238.12 EKX45740.1 - 4.2e-07 30.4 7.2 0.00032 21.3 0.3 3.4 3 0 0 3 3 3 2 Sel1 repeat TPR_6 PF13174.6 EKX45740.1 - 0.11 13.2 6.5 2.1 9.2 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat F5_F8_type_C PF00754.25 EKX45741.1 - 4.6e-17 62.3 0.9 4.9e-17 62.2 0.9 1.0 1 0 0 1 1 1 1 F5/8 type C domain F5_F8_type_C PF00754.25 EKX45742.1 - 5.2e-27 94.5 1.7 5.7e-27 94.3 1.7 1.0 1 0 0 1 1 1 1 F5/8 type C domain SRCR PF00530.18 EKX45743.1 - 8.4e-11 42.3 0.3 8.8e-11 42.2 0.3 1.0 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain TPR_1 PF00515.28 EKX45744.1 - 1.3e-19 69.1 26.8 6.2e-05 22.6 0.1 10.4 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_2 PF07719.17 EKX45744.1 - 3e-14 51.9 27.7 0.036 14.2 0.1 11.2 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_17 PF13431.6 EKX45744.1 - 8.4e-10 38.3 8.1 0.046 14.1 0.3 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX45744.1 - 2e-09 38.0 27.2 0.016 15.8 2.3 7.1 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 EKX45744.1 - 1.6e-08 34.7 20.9 2.6e-06 27.6 1.1 6.2 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX45744.1 - 3.5e-08 33.0 20.9 0.039 13.6 0.0 7.5 8 0 0 8 8 8 3 TPR repeat TPR_9 PF13371.6 EKX45744.1 - 1.9e-07 31.1 16.6 0.017 15.3 2.0 5.2 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EKX45744.1 - 7.9e-07 29.5 19.8 0.065 13.8 0.6 6.3 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX45744.1 - 6.4e-05 23.4 22.8 0.12 13.2 0.2 8.5 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX45744.1 - 0.00015 21.7 26.5 0.79 10.1 0.1 9.9 10 0 0 10 10 10 2 Tetratricopeptide repeat DUF627 PF04781.12 EKX45744.1 - 0.069 13.2 2.9 0.18 11.8 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF627) ANAPC3 PF12895.7 EKX45744.1 - 0.092 13.0 21.5 0.059 13.6 1.4 6.3 5 2 2 7 7 6 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 EKX45744.1 - 0.2 11.7 3.3 0.34 10.9 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Roc PF08477.13 EKX45745.1 - 1.5e-12 47.8 0.1 5.7e-06 26.5 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.32 EKX45745.1 - 6.5e-09 34.7 0.8 9.1e-05 21.7 0.1 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX45745.1 - 1.5e-07 31.7 0.6 7.4e-07 29.5 0.6 2.4 1 0 0 1 1 1 1 EF-hand domain pair COR PF16095.5 EKX45745.1 - 3e-07 30.5 0.1 7e-07 29.2 0.1 1.6 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Ras PF00071.22 EKX45745.1 - 2.4e-06 27.2 0.2 0.092 12.3 0.1 2.5 2 0 0 2 2 2 2 Ras family EF-hand_6 PF13405.6 EKX45745.1 - 3.2e-06 26.6 3.6 0.0051 16.6 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 EKX45745.1 - 1.9e-05 23.9 3.4 0.00019 20.8 0.3 3.1 2 0 0 2 2 2 1 EF hand TIR_2 PF13676.6 EKX45745.1 - 0.0006 20.4 0.0 0.0024 18.5 0.0 2.1 2 0 0 2 2 2 1 TIR domain SPARC_Ca_bdg PF10591.9 EKX45745.1 - 0.0011 19.2 0.1 0.0043 17.4 0.1 2.0 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Pkinase PF00069.25 EKX45746.1 - 4.1e-43 147.6 0.0 4.6e-43 147.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX45746.1 - 4.9e-38 130.9 0.0 5.4e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX45746.1 - 1.7e-10 40.3 0.0 2.7e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EKX45746.1 - 7.2e-07 28.8 0.0 5.5e-06 25.9 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EKX45746.1 - 2.8e-06 26.8 0.1 3.5e-06 26.5 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX45746.1 - 1.4e-05 25.1 0.0 0.0023 17.9 0.0 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EKX45746.1 - 0.002 17.2 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 YrbL-PhoP_reg PF10707.9 EKX45746.1 - 0.0031 17.1 0.1 0.0085 15.6 0.0 1.7 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL FTA2 PF13095.6 EKX45746.1 - 0.0099 15.5 0.0 0.021 14.5 0.0 1.6 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EKX45746.1 - 0.022 13.7 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain PIP49_C PF12260.8 EKX45746.1 - 0.15 11.7 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Pkinase PF00069.25 EKX45747.1 - 5.2e-12 45.7 0.3 2e-11 43.8 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX45747.1 - 4.1e-08 32.8 0.0 1.3e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX45747.1 - 0.0016 17.8 0.0 0.0016 17.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Cornifin PF02389.15 EKX45747.1 - 0.048 13.9 0.2 0.096 12.9 0.2 1.4 1 0 0 1 1 1 0 Cornifin (SPRR) family EspA PF03433.13 EKX45747.1 - 0.096 12.5 4.3 0.067 13.0 0.6 2.6 2 1 1 3 3 3 0 EspA-like secreted protein Vip3A_N PF12495.8 EKX45747.1 - 0.17 11.8 1.3 0.31 10.9 0.7 1.7 1 1 0 1 1 1 0 Vegetative insecticide protein 3A N terminal NPV_P10 PF05531.12 EKX45747.1 - 0.5 10.9 2.7 5.7 7.5 0.7 3.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 EKX45747.1 - 1.5 8.9 10.9 3.1 7.9 3.4 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) LHH PF14411.6 EKX45748.1 - 0.016 15.3 0.4 3.2 8.0 0.0 3.4 2 0 0 2 2 2 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH ATG_C PF09333.11 EKX45748.1 - 0.096 13.0 0.7 27 5.2 0.1 3.0 2 1 0 2 2 2 0 Autophagy-related protein C terminal domain DUF148 PF02520.17 EKX45748.1 - 0.16 12.1 9.3 0.044 13.9 3.5 3.2 2 1 0 2 2 2 0 Domain of unknown function DUF148 Baculo_PEP_C PF04513.12 EKX45748.1 - 4.1 7.4 8.0 0.51 10.4 0.4 3.3 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mito_carr PF00153.27 EKX45752.1 - 1.8e-43 146.4 0.3 2.6e-17 62.5 0.0 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein Gly-zipper_YMGG PF13441.6 EKX45752.1 - 0.021 14.5 7.5 0.1 12.3 0.4 2.5 2 0 0 2 2 2 0 YMGG-like Gly-zipper DUF3482 PF11981.8 EKX45752.1 - 0.074 12.4 4.5 0.9 8.9 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) Bacteriocin_IIc PF10439.9 EKX45752.1 - 0.15 12.2 5.5 4.3 7.5 0.8 2.4 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DUF229 PF02995.17 EKX45753.1 - 4.8e-45 154.1 0.0 1.9e-33 115.8 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF229) DUF393 PF04134.12 EKX45754.1 - 4.2e-25 89.3 0.2 9.4e-25 88.2 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF393 YjgF_endoribonc PF14588.6 EKX45755.1 - 1.1e-14 54.9 0.0 1.5e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 EKX45755.1 - 0.00012 22.0 0.0 0.00019 21.4 0.0 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP Thioredoxin_3 PF13192.6 EKX45755.1 - 0.18 11.9 0.1 0.38 10.8 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin domain LVIVD PF08309.11 EKX45755.1 - 0.18 11.1 2.0 0.42 10.0 2.0 1.5 1 0 0 1 1 1 0 LVIVD repeat ALG3 PF05208.13 EKX45756.1 - 1.8e-100 336.9 17.0 3e-100 336.1 17.0 1.3 1 0 0 1 1 1 1 ALG3 protein CwfJ_C_2 PF04676.14 EKX45757.1 - 2e-13 51.0 0.0 2.2e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 HTH_Tnp_ISL3 PF13542.6 EKX45757.1 - 0.16 11.4 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 RRM_1 PF00076.22 EKX45758.1 - 5.2e-13 48.6 0.1 9.5e-13 47.8 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DOT1 PF08123.13 EKX45759.1 - 2e-05 24.2 0.0 0.0001 21.9 0.0 1.9 1 1 0 1 1 1 1 Histone methylation protein DOT1 AdoMet_MTase PF07757.13 EKX45759.1 - 0.012 16.0 0.0 0.022 15.1 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase PrmA PF06325.13 EKX45759.1 - 0.021 14.2 0.6 0.047 13.1 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EKX45759.1 - 0.057 13.0 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 EKX45759.1 - 0.13 12.1 0.2 0.48 10.2 0.2 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EKX45759.1 - 0.2 12.4 0.3 0.65 10.7 0.1 2.0 2 1 0 2 2 2 0 Methyltransferase domain GNT-I PF03071.15 EKX45760.1 - 1e-06 27.8 0.0 1.7e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 GNT-I family MGAT2 PF05060.14 EKX45760.1 - 0.0076 15.4 0.0 0.088 11.9 0.0 2.2 2 0 0 2 2 2 1 N-acetylglucosaminyltransferase II (MGAT2) Pyr_redox_2 PF07992.14 EKX45764.1 - 1.3e-54 185.5 0.0 1.5e-54 185.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EKX45764.1 - 8.6e-24 83.9 0.0 1.6e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EKX45764.1 - 7.5e-15 55.3 1.0 6e-11 42.8 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EKX45764.1 - 1.3e-10 41.0 0.1 9.6e-08 31.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EKX45764.1 - 1.6e-06 27.5 1.6 2e-05 23.9 1.4 2.3 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 EKX45764.1 - 9.4e-06 25.1 0.0 0.00053 19.4 0.0 2.7 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 EKX45764.1 - 0.00024 20.6 0.4 0.00041 19.8 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EKX45764.1 - 0.00031 19.9 1.6 0.00063 18.9 1.6 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 EKX45764.1 - 0.0011 17.8 0.4 0.011 14.5 0.3 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EKX45764.1 - 0.0076 15.5 0.3 0.014 14.7 0.3 1.4 1 0 0 1 1 1 1 Thi4 family Phage_holin_2_3 PF16080.5 EKX45764.1 - 0.042 13.6 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage holin family HP1 K_oxygenase PF13434.6 EKX45764.1 - 0.09 11.9 0.0 0.46 9.6 0.0 2.1 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EKX45764.1 - 0.41 10.9 4.7 0.12 12.6 0.6 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Sulfate_transp PF00916.20 EKX45765.1 - 1.9e-94 316.6 14.8 2.2e-94 316.3 14.8 1.0 1 0 0 1 1 1 1 Sulfate permease family MFS_MOT1 PF16983.5 EKX45765.1 - 0.0023 18.3 5.9 0.0023 18.3 5.9 3.5 3 1 0 3 3 3 1 Molybdate transporter of MFS superfamily PsbH PF00737.20 EKX45765.1 - 2.4 7.9 7.3 3 7.6 1.0 3.0 2 1 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein Wzy_C PF04932.15 EKX45765.1 - 9.4 5.8 10.4 1.3 8.7 3.1 2.5 2 0 0 2 2 2 0 O-Antigen ligase WD40 PF00400.32 EKX45767.1 - 4.3e-18 65.3 6.1 6.2e-05 23.7 0.1 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX45767.1 - 8.6e-06 26.0 0.0 0.12 12.7 0.0 4.6 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain HPS3_N PF14761.6 EKX45767.1 - 0.00079 19.0 0.3 0.0063 16.1 0.0 2.4 3 0 0 3 3 3 1 Hermansky-Pudlak syndrome 3 eIF2A PF08662.11 EKX45767.1 - 0.0016 18.3 0.1 0.066 13.1 0.0 3.0 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EKX45767.1 - 0.0023 16.9 1.0 1.4 7.8 0.0 3.8 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4834 PF16118.5 EKX45767.1 - 0.011 16.6 0.5 0.019 15.9 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SpoIIIAH PF12685.7 EKX45767.1 - 0.015 15.1 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein YqfD PF06898.11 EKX45767.1 - 0.054 12.3 1.8 0.12 11.2 1.8 1.5 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD Svs_4_5_6 PF17381.2 EKX45767.1 - 0.055 14.4 2.5 0.11 13.5 2.5 1.4 1 0 0 1 1 1 0 Seminal vesicle secretory proteins 4/5/6 Coatomer_WDAD PF04053.14 EKX45767.1 - 0.061 12.4 0.0 6.4 5.7 0.0 2.4 2 1 0 2 2 2 0 Coatomer WD associated region DUF2681 PF10883.8 EKX45767.1 - 0.07 13.5 1.6 0.15 12.4 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) UPF0239 PF06783.11 EKX45767.1 - 0.13 12.5 5.6 0.25 11.6 5.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) Peptidase_S49_N PF08496.10 EKX45767.1 - 0.16 12.0 1.0 0.32 11.0 1.0 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CBP_BcsG PF11658.8 EKX45767.1 - 0.21 10.0 0.2 0.28 9.6 0.2 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG MAP17 PF15807.5 EKX45767.1 - 0.32 11.2 1.9 0.58 10.4 1.9 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 YqfQ PF14181.6 EKX45767.1 - 0.49 10.6 5.4 1.1 9.5 5.4 1.5 1 0 0 1 1 1 0 YqfQ-like protein Metallophos PF00149.28 EKX45768.1 - 1.9e-26 93.8 0.1 3.5e-26 93.0 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_8 PF13833.6 EKX45768.1 - 0.022 14.6 0.0 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 EKX45768.1 - 0.099 12.6 0.0 0.31 11.1 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 EKX45768.1 - 0.14 11.7 1.1 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 EF hand DUF3854 PF12965.7 EKX45769.1 - 0.092 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) Beta_elim_lyase PF01212.21 EKX45769.1 - 0.15 11.3 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase DUF1690 PF07956.11 EKX45769.1 - 0.22 12.0 4.9 1.5 9.2 5.3 2.2 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) EGF PF00008.27 EKX45771.1 - 0.0018 18.5 4.6 0.0068 16.7 4.6 2.1 1 0 0 1 1 1 1 EGF-like domain O-FucT PF10250.9 EKX45771.1 - 0.042 13.6 0.0 0.12 12.0 0.0 1.6 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase EGF_CA PF07645.15 EKX45771.1 - 5.2 7.4 8.6 22 5.3 8.6 2.1 1 0 0 1 1 1 0 Calcium-binding EGF domain N_Asn_amidohyd PF14736.6 EKX45772.1 - 2.8e-37 128.4 0.0 3.6e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase CBFD_NFYB_HMF PF00808.23 EKX45773.1 - 5.9e-13 48.9 0.3 1.3e-12 47.7 0.3 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EKX45773.1 - 9.8e-08 32.4 0.1 9.8e-08 32.4 0.1 3.1 2 1 0 3 3 3 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EKX45773.1 - 0.031 14.4 0.1 0.06 13.5 0.1 1.5 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold VWA_2 PF13519.6 EKX45774.1 - 1.5e-10 41.6 0.0 2.3e-09 37.8 0.0 2.4 1 1 1 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 EKX45774.1 - 4.3e-05 23.4 0.1 7.3e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 EKX45774.1 - 0.0013 18.5 11.3 0.0067 16.3 4.2 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif ADIP PF11559.8 EKX45775.1 - 0.0081 16.3 4.5 0.01 15.9 4.5 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding NBP1 PF08537.10 EKX45775.1 - 0.0081 15.6 3.0 0.009 15.5 3.0 1.1 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 DUF2205 PF10224.9 EKX45775.1 - 0.026 14.5 2.5 0.04 13.9 2.5 1.3 1 0 0 1 1 1 0 Short coiled-coil protein APG6_N PF17675.1 EKX45775.1 - 0.029 14.9 3.3 0.036 14.6 3.3 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Prefoldin PF02996.17 EKX45775.1 - 0.21 11.5 4.7 0.27 11.1 4.7 1.2 1 0 0 1 1 1 0 Prefoldin subunit DUF5320 PF17253.2 EKX45775.1 - 0.9 10.6 2.3 0.95 10.6 0.7 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5320) DNMT1-RFD PF12047.8 EKX45776.1 - 0.00095 19.2 0.1 0.0011 19.0 0.1 1.1 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain Rb_C PF08934.10 EKX45776.1 - 0.0063 16.3 0.3 0.0066 16.3 0.3 1.0 1 0 0 1 1 1 1 Rb C-terminal domain Yop-YscD_cpl PF16697.5 EKX45778.1 - 7.7e-12 45.4 0.1 1.8e-10 41.0 0.0 2.7 3 0 0 3 3 3 1 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 EKX45778.1 - 9.6e-12 45.1 0.0 1.9e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain LRR_6 PF13516.6 EKX45778.1 - 5.2e-09 35.4 13.9 0.41 10.8 0.2 9.1 10 0 0 10 10 10 4 Leucine Rich repeat LRR_4 PF12799.7 EKX45778.1 - 6.3e-06 26.4 5.0 0.00064 20.1 0.3 4.6 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX45778.1 - 5.4e-05 23.2 10.3 1.4 9.8 0.1 6.8 6 0 0 6 6 6 1 Leucine Rich Repeat CPBP PF02517.16 EKX45779.1 - 1.2e-08 35.2 3.6 1.2e-08 35.2 3.6 2.4 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease DUF4209 PF13910.6 EKX45782.1 - 4.7e-16 58.8 0.0 1.4e-14 54.0 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4209) HBM PF16591.5 EKX45782.1 - 0.0046 16.4 3.9 0.13 11.7 0.3 2.4 2 0 0 2 2 2 2 Helical bimodular sensor domain TPR_MLP1_2 PF07926.12 EKX45782.1 - 0.017 15.1 3.2 0.051 13.6 3.2 1.7 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Ribosomal_L2_C PF03947.18 EKX45783.1 - 0.02 15.1 0.1 0.036 14.3 0.1 1.4 1 0 0 1 1 1 0 Ribosomal Proteins L2, C-terminal domain Ig_mannosidase PF17753.1 EKX45785.1 - 0.038 13.7 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 Ig-fold domain Nudix_N_2 PF14803.6 EKX45785.1 - 0.56 10.2 3.1 2.8 7.9 0.2 2.9 3 0 0 3 3 3 0 Nudix N-terminal LRR_8 PF13855.6 EKX45786.1 - 7e-12 44.9 5.7 7.6e-07 28.8 0.4 2.3 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EKX45786.1 - 2.8e-08 33.9 7.7 0.00081 19.7 1.1 2.9 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX45786.1 - 1.6e-07 30.9 4.9 1.3 9.8 0.0 4.3 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_6 PF13516.6 EKX45786.1 - 0.00046 20.0 2.8 4.1 7.7 0.0 3.5 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.7 EKX45787.1 - 3.8e-19 68.4 9.1 0.0037 17.6 0.2 5.1 4 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX45787.1 - 2.6e-18 65.5 13.7 5.5e-07 29.2 1.3 4.2 1 1 4 5 5 5 5 Leucine rich repeat LRR_1 PF00560.33 EKX45787.1 - 2.4e-11 42.5 9.2 0.38 11.5 0.0 7.8 8 0 0 8 8 8 5 Leucine Rich Repeat LRR_6 PF13516.6 EKX45787.1 - 3.3e-05 23.6 9.5 0.29 11.3 0.1 5.6 6 0 0 6 6 6 2 Leucine Rich repeat LRR_9 PF14580.6 EKX45787.1 - 0.025 14.1 0.1 3.1 7.3 0.0 2.4 1 1 0 2 2 2 0 Leucine-rich repeat MORN PF02493.20 EKX45788.1 - 4.2e-14 51.5 61.0 0.00069 19.4 1.5 7.3 7 0 0 7 7 7 7 MORN repeat Nbl1_Borealin_N PF10444.9 EKX45789.1 - 0.025 14.2 0.0 0.025 14.2 0.0 2.8 3 1 1 4 4 4 0 Nbl1 / Borealin N terminal Bax1-I PF01027.20 EKX45790.1 - 2e-30 106.2 28.0 2.3e-30 106.0 28.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Phenol_Hydrox PF02332.18 EKX45790.1 - 0.0094 15.5 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 Methane/Phenol/Toluene Hydroxylase Urate_ox_N PF06181.11 EKX45790.1 - 0.63 9.3 10.1 0.032 13.6 3.0 2.1 2 1 0 2 2 2 0 Urate oxidase N-terminal DUF4050 PF13259.6 EKX45791.1 - 0.00016 22.0 13.8 0.00051 20.4 0.9 3.1 1 1 2 3 3 3 2 Protein of unknown function (DUF4050) LETM1 PF07766.13 EKX45792.1 - 8.6e-92 307.3 1.6 8.6e-92 307.3 1.6 1.5 2 0 0 2 2 2 1 LETM1-like protein CsgG PF03783.14 EKX45792.1 - 0.18 11.0 1.7 0.68 9.2 0.7 2.0 2 0 0 2 2 2 0 Curli production assembly/transport component CsgG Proteasome PF00227.26 EKX45793.1 - 1.1e-46 158.7 0.1 2.6e-46 157.5 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 EKX45793.1 - 1.4e-10 40.7 0.5 2.2e-10 40.0 0.5 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature TIR_2 PF13676.6 EKX45794.1 - 9.2e-17 61.7 0.2 9.8e-16 58.4 0.1 2.6 2 0 0 2 2 2 1 TIR domain Roc PF08477.13 EKX45794.1 - 2.6e-13 50.2 0.0 8.5e-13 48.6 0.0 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 EKX45794.1 - 5.7e-13 49.1 0.0 1.6e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Ras PF00071.22 EKX45794.1 - 5.8e-06 26.0 0.0 1.4e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Ras family Arf PF00025.21 EKX45794.1 - 1.3e-05 24.8 0.4 2.8e-05 23.7 0.1 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EKX45794.1 - 2.5e-05 23.8 0.0 5.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EKX45794.1 - 0.0012 18.9 0.0 0.0058 16.7 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase TIR PF01582.20 EKX45794.1 - 0.0052 16.6 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 TIR domain GTP_EFTU PF00009.27 EKX45794.1 - 0.029 13.9 0.1 3.9 7.0 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain G-alpha PF00503.20 EKX45794.1 - 0.048 12.8 0.1 0.18 11.0 0.0 1.8 1 1 1 2 2 2 0 G-protein alpha subunit Pkinase PF00069.25 EKX45796.1 - 7.2e-36 123.9 0.0 8.4e-36 123.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX45796.1 - 7.2e-31 107.4 0.0 8.1e-31 107.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase PIP49_C PF12260.8 EKX45796.1 - 0.029 14.0 0.0 0.037 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 APH PF01636.23 EKX45796.1 - 0.17 11.8 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family OTU PF02338.19 EKX45797.1 - 2.5e-18 66.8 0.0 9.2e-18 65.0 0.0 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EKX45797.1 - 3e-05 23.6 5.6 0.012 15.1 0.1 2.8 3 0 0 3 3 3 2 Peptidase C65 Otubain Secretin_N_2 PF07655.13 EKX45797.1 - 4.4 7.9 14.1 8.6 7.0 14.1 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain Collagen PF01391.18 EKX45799.1 - 3.7e-06 26.6 36.4 2.3e-05 24.1 36.4 2.0 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Metal_resist PF13801.6 EKX45799.1 - 5 7.3 8.1 7.1 6.8 0.2 2.7 3 0 0 3 3 3 0 Heavy-metal resistance PhyH PF05721.13 EKX45801.1 - 1.7e-07 31.7 0.9 1.7e-07 31.7 0.9 2.2 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) PAF-AH_p_II PF03403.13 EKX45802.1 - 0.022 13.3 0.3 0.031 12.8 0.3 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II UPF0047 PF01894.17 EKX45804.1 - 0.069 13.3 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0047 FAM212 PF15342.6 EKX45804.1 - 0.43 10.4 3.7 13 5.7 0.1 2.7 2 1 1 3 3 3 0 FAM212 family DnaJ PF00226.31 EKX45805.1 - 5.2e-21 74.5 0.3 5.6e-21 74.4 0.3 1.0 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.25 EKX45806.1 - 1.3e-43 149.3 0.1 8.7e-43 146.6 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain PHY PF00360.20 EKX45806.1 - 2e-25 89.2 0.0 3.2e-12 46.1 0.0 2.3 2 0 0 2 2 2 2 Phytochrome region Pkinase_Tyr PF07714.17 EKX45806.1 - 5.1e-23 81.7 0.0 2e-22 79.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase zf-C3HC4_2 PF13923.6 EKX45806.1 - 4e-08 33.0 8.3 1.1e-07 31.5 8.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX45806.1 - 1e-07 32.1 7.6 3e-07 30.7 7.6 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EKX45806.1 - 7.3e-05 22.5 6.5 0.00019 21.2 6.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX45806.1 - 0.00016 21.5 7.7 0.00042 20.1 7.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Kdo PF06293.14 EKX45806.1 - 0.00053 19.4 0.0 0.0014 18.1 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX45806.1 - 0.00086 19.3 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-rbx1 PF12678.7 EKX45806.1 - 0.0013 19.0 8.1 0.0044 17.3 8.1 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain Pkinase_fungal PF17667.1 EKX45806.1 - 0.0014 17.5 0.0 0.0029 16.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase GAF PF01590.26 EKX45806.1 - 0.0051 17.4 0.0 0.017 15.8 0.0 2.0 1 0 0 1 1 1 1 GAF domain PAS PF00989.25 EKX45806.1 - 0.019 15.0 0.0 1.4 8.9 0.0 3.0 2 0 0 2 2 2 0 PAS fold zf-RING_5 PF14634.6 EKX45806.1 - 0.045 13.7 7.7 0.12 12.4 7.0 2.2 1 1 0 1 1 1 0 zinc-RING finger domain PAS_4 PF08448.10 EKX45806.1 - 0.047 13.9 0.0 0.22 11.8 0.0 2.1 2 0 0 2 2 1 0 PAS fold PAS_2 PF08446.11 EKX45806.1 - 0.057 14.1 0.0 0.37 11.5 0.0 2.6 2 0 0 2 2 1 0 PAS fold Kinase-like PF14531.6 EKX45806.1 - 0.1 11.9 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like zf-P11 PF03854.14 EKX45806.1 - 0.13 11.9 7.9 0.61 9.8 7.2 2.3 1 1 0 1 1 1 0 P-11 zinc finger Prok-RING_4 PF14447.6 EKX45806.1 - 0.24 11.3 8.8 0.6 10.0 8.8 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EKX45806.1 - 0.44 10.6 6.8 0.99 9.5 6.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DUF1272 PF06906.11 EKX45806.1 - 0.77 9.9 8.4 10 6.3 8.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-RING_6 PF14835.6 EKX45806.1 - 1.4 8.8 4.4 4.2 7.3 4.4 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 EKX45806.1 - 2.2 8.0 10.0 7.1 6.3 10.0 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type B12D PF06522.11 EKX45807.1 - 2.6e-05 23.9 0.0 4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit adh_short_C2 PF13561.6 EKX45808.1 - 7e-40 137.0 0.0 8.7e-40 136.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EKX45808.1 - 6.5e-28 97.5 0.0 8.9e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EKX45808.1 - 7.8e-09 35.7 0.1 1.7e-08 34.6 0.0 1.6 1 1 1 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 EKX45808.1 - 0.00062 20.0 0.1 0.001 19.3 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 EKX45808.1 - 0.0013 19.3 0.5 0.0028 18.2 0.5 1.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 EKX45808.1 - 0.0025 17.7 0.1 0.0043 17.0 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 EKX45808.1 - 0.0067 15.9 0.0 0.0098 15.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 EKX45808.1 - 0.0068 16.6 0.0 0.014 15.5 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_zinc_N PF00107.26 EKX45808.1 - 0.021 14.8 0.3 0.45 10.5 0.0 2.5 2 1 0 2 2 2 0 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 EKX45808.1 - 0.074 12.9 0.6 0.16 11.9 0.6 1.6 1 1 0 1 1 1 0 NAD(P)H-binding Methyltransf_24 PF13578.6 EKX45808.1 - 0.16 13.0 0.1 0.91 10.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Ank_5 PF13857.6 EKX45810.1 - 1.5e-09 37.9 1.2 7.4e-08 32.5 0.1 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX45810.1 - 1e-06 29.2 0.2 1.7e-06 28.5 0.2 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX45810.1 - 1.6e-05 24.9 0.3 0.0033 17.8 0.2 3.0 2 1 1 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EKX45810.1 - 0.0013 19.3 0.0 0.0029 18.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX45810.1 - 0.0019 18.6 1.2 0.0093 16.4 0.6 2.3 3 0 0 3 3 3 1 Ankyrin repeat HlyU PF10115.9 EKX45811.1 - 0.077 13.1 0.0 20 5.3 0.0 2.6 2 0 0 2 2 2 0 Transcriptional activator HlyU MCR_beta PF02241.18 EKX45812.1 - 0.081 12.5 0.3 0.12 11.9 0.3 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain FTCD_C PF04961.12 EKX45812.1 - 0.21 11.4 1.5 1.3 8.8 1.0 2.0 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase PGAP1 PF07819.13 EKX45813.1 - 3.3e-07 30.3 0.0 5.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EKX45813.1 - 0.00014 22.5 0.2 0.00019 22.1 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EKX45813.1 - 0.04 13.6 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Palm_thioest PF02089.15 EKX45813.1 - 0.046 13.5 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase FAD-oxidase_C PF02913.19 EKX45814.1 - 4.1e-47 160.9 0.0 5.7e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EKX45814.1 - 5.3e-36 123.4 0.1 9.6e-36 122.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EKX45814.1 - 0.037 14.1 0.0 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 Berberine and berberine like Ank_2 PF12796.7 EKX45817.1 - 4.2e-07 30.5 0.0 0.0077 16.8 0.0 3.1 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX45817.1 - 1e-06 29.2 1.7 0.074 13.7 0.0 3.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX45817.1 - 4.1e-06 26.7 1.4 0.77 10.5 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EKX45817.1 - 5.6e-05 23.3 0.1 0.29 11.5 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX45817.1 - 0.0032 17.9 1.0 2.1 9.0 0.1 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ion_trans PF00520.31 EKX45817.1 - 0.76 8.9 22.8 0.73 9.0 18.5 2.6 1 1 1 2 2 2 0 Ion transport protein DUF4370 PF14290.6 EKX45818.1 - 0.11 12.4 0.2 0.16 11.8 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4370) Peptidase_S58 PF03576.14 EKX45819.1 - 0.07 12.6 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Peptidase family S58 LIF_OSM PF01291.17 EKX45819.1 - 0.16 12.1 2.3 2.2 8.4 0.1 3.2 3 0 0 3 3 3 0 LIF / OSM family Laminin_II PF06009.12 EKX45819.1 - 3.7 7.6 41.6 4.1 7.4 0.3 6.1 5 1 1 6 6 6 0 Laminin Domain II Flu_NS2 PF00601.19 EKX45819.1 - 3.8 7.9 8.0 0.75 10.1 0.2 3.5 3 0 0 3 3 3 0 Influenza non-structural protein (NS2) DUF948 PF06103.11 EKX45819.1 - 6.6 7.1 10.9 11 6.4 0.5 4.7 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) WXG100 PF06013.12 EKX45819.1 - 7.6 6.8 20.7 4.9 7.5 1.0 5.5 3 2 1 4 4 4 0 Proteins of 100 residues with WXG PDZ_6 PF17820.1 EKX45820.1 - 1.5e-05 24.7 0.0 2.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX45820.1 - 0.0013 19.1 0.0 0.0019 18.5 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX45820.1 - 0.0036 17.6 0.0 0.015 15.6 0.0 1.8 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 EKX45820.1 - 0.0043 17.0 0.0 0.0071 16.3 0.0 1.3 1 0 0 1 1 1 1 Tricorn protease PDZ domain Ribosomal_L29 PF00831.23 EKX45820.1 - 0.19 11.7 0.6 0.27 11.2 0.1 1.5 2 0 0 2 2 2 0 Ribosomal L29 protein Olduvai PF06758.13 EKX45821.1 - 0.0026 18.0 1.8 0.0055 16.9 1.1 1.8 1 1 1 2 2 2 1 Olduvai domain LRRNT_2 PF08263.12 EKX45821.1 - 0.98 9.8 4.2 2.3 8.6 4.2 1.8 1 1 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_8 PF13855.6 EKX45822.1 - 3.6e-44 148.3 69.5 1.8e-11 43.6 6.9 8.6 2 1 8 11 11 11 11 Leucine rich repeat LRR_4 PF12799.7 EKX45822.1 - 8.9e-34 115.0 71.7 2.7e-05 24.5 0.3 11.1 3 3 11 14 14 14 14 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX45822.1 - 7.3e-12 44.1 58.0 6.9 7.7 2.4 15.8 14 2 0 14 14 14 6 Leucine Rich Repeat LRR_5 PF13306.6 EKX45822.1 - 1.6e-05 24.9 9.1 0.00097 19.1 1.5 4.6 2 1 2 5 5 5 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 EKX45822.1 - 9.2e-05 22.0 29.3 0.0043 16.6 2.7 4.6 1 1 4 5 5 5 4 Leucine-rich repeat LRR_6 PF13516.6 EKX45822.1 - 0.14 12.3 58.8 0.43 10.8 0.2 12.4 14 0 0 14 14 14 0 Leucine Rich repeat RWP-RK PF02042.15 EKX45823.1 - 1.2e-13 50.8 0.0 2.1e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain Comm PF15957.5 EKX45824.1 - 0.0045 17.3 0.1 0.0092 16.3 0.0 1.6 2 0 0 2 2 2 1 Commissureless RWP-RK PF02042.15 EKX45825.1 - 7.9e-14 51.4 0.0 1.4e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX45827.1 - 1.4e-13 50.6 0.0 2.6e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX45829.1 - 3.6e-14 52.5 0.0 6.1e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX45830.1 - 0.023 14.7 0.1 0.037 14.0 0.1 1.3 1 0 0 1 1 1 0 RWP-RK domain Comm PF15957.5 EKX45831.1 - 0.016 15.6 0.0 0.037 14.4 0.0 1.6 2 0 0 2 2 2 0 Commissureless RWP-RK PF02042.15 EKX45832.1 - 0.024 14.6 0.1 0.04 13.9 0.1 1.3 1 0 0 1 1 1 0 RWP-RK domain Comm PF15957.5 EKX45833.1 - 0.013 15.8 0.0 0.03 14.7 0.0 1.6 2 0 0 2 2 2 0 Commissureless DUF829 PF05705.14 EKX45834.1 - 1.1e-16 61.5 0.0 1.8e-16 60.8 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) PKD_channel PF08016.12 EKX45835.1 - 8.2e-28 97.2 12.9 1.6e-18 66.7 12.8 2.2 2 0 0 2 2 2 2 Polycystin cation channel Ion_trans PF00520.31 EKX45835.1 - 2e-14 53.4 15.4 3.3e-14 52.7 15.4 1.3 1 0 0 1 1 1 1 Ion transport protein RHH_3 PF12651.7 EKX45835.1 - 0.0055 16.6 0.0 0.018 15.0 0.1 1.8 2 0 0 2 2 2 1 Ribbon-helix-helix domain DUF3198 PF11433.8 EKX45835.1 - 0.06 13.3 0.6 0.14 12.1 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3198) DUF382 PF04037.13 EKX45836.1 - 2.1e-56 189.5 0.7 2.1e-56 189.5 0.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 EKX45836.1 - 1.6e-20 72.7 3.4 3.7e-20 71.5 3.4 1.7 1 0 0 1 1 1 1 PSP DUF5364 PF17322.2 EKX45836.1 - 0.0045 17.3 3.9 0.013 15.8 0.9 2.1 2 0 0 2 2 2 1 Family of unknown function (DUF5364) TBCC_N PF16752.5 EKX45837.1 - 0.026 14.9 3.6 0.026 14.9 3.6 1.7 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain WW PF00397.26 EKX45838.1 - 4.9e-09 36.1 29.9 4.7e-06 26.6 5.5 3.4 3 0 0 3 3 3 2 WW domain Cyclase PF04199.13 EKX45838.1 - 0.045 14.0 3.1 0.77 10.0 0.0 2.6 2 1 0 2 2 2 0 Putative cyclase SDA1 PF05285.12 EKX45838.1 - 8.8 5.6 14.6 35 3.7 14.6 1.8 1 1 0 1 1 1 0 SDA1 zf-HIT PF04438.16 EKX45839.1 - 3.7 7.5 12.3 0.35 10.8 7.3 1.9 2 0 0 2 2 2 0 HIT zinc finger tRNA-synt_2_TM PF16995.5 EKX45840.1 - 0.018 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Transmembrane region of lysyl-tRNA synthetase PIG-S PF10510.9 EKX45841.1 - 0.01 14.7 4.7 0.67 8.7 0.2 2.3 2 0 0 2 2 2 0 Phosphatidylinositol-glycan biosynthesis class S protein Helicase_C PF00271.31 EKX45843.1 - 8.4e-19 68.0 0.1 2.5e-18 66.5 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UvrB PF12344.8 EKX45843.1 - 5.4e-17 61.4 0.0 9.6e-17 60.6 0.0 1.4 1 0 0 1 1 1 1 Ultra-violet resistance protein B ResIII PF04851.15 EKX45843.1 - 1.5e-08 34.9 0.0 1e-07 32.1 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EKX45843.1 - 8.7e-06 25.6 0.0 0.00017 21.4 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EKX45843.1 - 3.3e-05 23.7 0.0 0.00015 21.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EKX45843.1 - 0.0033 17.8 0.1 5.4 7.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain UvrD-helicase PF00580.21 EKX45843.1 - 0.016 14.8 2.2 0.47 9.9 0.0 2.5 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 EKX45843.1 - 0.035 14.4 0.0 0.18 12.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EKX45843.1 - 0.036 14.0 0.2 6.3 6.7 0.1 2.6 2 0 0 2 2 2 0 NACHT domain AbiTii PF18864.1 EKX45843.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 AbiTii AAA_25 PF13481.6 EKX45843.1 - 0.12 12.0 0.0 0.32 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain UvrC_HhH_N PF08459.11 EKX45844.1 - 5e-24 85.0 0.0 3.1e-23 82.4 0.0 2.1 1 1 0 1 1 1 1 UvrC Helix-hairpin-helix N-terminal HHH_2 PF12826.7 EKX45844.1 - 0.0077 16.3 0.2 0.031 14.4 0.1 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EKX45844.1 - 0.035 14.7 0.1 0.12 13.0 0.1 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain BSMAP PF12280.8 EKX45845.1 - 0.0092 16.2 0.1 0.15 12.3 0.0 2.3 2 0 0 2 2 2 1 Brain specific membrane anchored protein SET PF00856.28 EKX45845.1 - 0.019 15.3 0.8 0.82 10.0 0.0 3.0 2 2 0 2 2 2 0 SET domain GAS PF13851.6 EKX45846.1 - 0.076 12.4 0.1 0.076 12.4 0.1 7.1 4 2 3 7 7 7 0 Growth-arrest specific micro-tubule binding Uteroglobin PF01099.17 EKX45846.1 - 0.49 10.8 5.3 4.6 7.6 1.5 3.4 3 0 0 3 3 3 0 Uteroglobin family Spc7 PF08317.11 EKX45847.1 - 5e-23 81.5 6.9 3.4e-22 78.7 6.9 2.0 1 1 0 1 1 1 1 Spc7 kinetochore protein Spc7_N PF15402.6 EKX45847.1 - 1.4e-09 36.9 6.6 1.4e-09 36.9 6.6 2.4 2 0 0 2 2 2 1 N-terminus of kinetochore NMS complex subunit Spc7 Syntaxin-6_N PF09177.11 EKX45847.1 - 0.11 13.1 8.1 3.7 8.2 0.7 3.3 1 1 2 3 3 3 0 Syntaxin 6, N-terminal YscJ_FliF PF01514.17 EKX45847.1 - 0.13 11.9 2.8 0.29 10.8 2.8 1.5 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family PHM7_cyt PF14703.6 EKX45847.1 - 0.3 11.3 1.9 0.47 10.7 0.6 2.0 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter TSC22 PF01166.18 EKX45847.1 - 0.56 10.6 3.4 24 5.4 0.2 3.1 3 0 0 3 3 3 0 TSC-22/dip/bun family DivIC PF04977.15 EKX45847.1 - 0.9 9.4 3.4 5.8 6.8 0.5 2.7 2 0 0 2 2 2 0 Septum formation initiator LPP PF04728.13 EKX45847.1 - 1.2 9.5 5.0 2.1 8.8 0.2 3.2 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Spc24 PF08286.11 EKX45847.1 - 1.3 9.3 9.6 5.3 7.3 0.7 3.5 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 E2F_CC-MB PF16421.5 EKX45847.1 - 1.6 9.1 4.5 5.7 7.4 0.4 2.7 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain Fib_alpha PF08702.10 EKX45847.1 - 1.8 8.8 8.5 6.9 6.8 0.1 3.3 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family SpoOE-like PF09388.10 EKX45847.1 - 5.4 7.0 7.5 0.45 10.5 0.1 3.0 3 0 0 3 3 3 0 Spo0E like sporulation regulatory protein Cg6151-P PF10233.9 EKX45848.1 - 9.2e-07 29.2 12.2 1.4e-06 28.6 12.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P TMEM72 PF16054.5 EKX45848.1 - 0.00041 20.1 3.0 0.00059 19.6 3.0 1.2 1 0 0 1 1 1 1 Transmembrane protein family 72 CRCB PF02537.15 EKX45848.1 - 0.015 15.6 3.8 0.027 14.8 3.8 1.4 1 0 0 1 1 1 0 CrcB-like protein, Camphor Resistance (CrcB) DUF1751 PF08551.10 EKX45848.1 - 0.049 14.2 3.5 0.17 12.5 0.7 2.4 1 1 1 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) Ank_2 PF12796.7 EKX45849.1 - 3.6e-06 27.5 0.0 7e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX45849.1 - 3.4e-05 24.0 0.3 9.2e-05 22.7 0.3 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX45849.1 - 5.2e-05 23.7 0.2 0.00014 22.3 0.2 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX45849.1 - 0.00049 20.3 0.1 0.13 12.9 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EKX45849.1 - 0.0013 19.1 0.0 0.0034 17.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat TF_Zn_Ribbon PF08271.12 EKX45849.1 - 0.0088 15.5 0.0 0.02 14.4 0.0 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Ephrin_rec_like PF07699.13 EKX45850.1 - 8e-12 44.7 20.1 4e-10 39.3 9.5 6.7 7 1 1 8 8 8 2 Putative ephrin-receptor like DUF4215 PF13948.6 EKX45850.1 - 0.0025 18.2 0.6 0.0025 18.2 0.6 5.1 5 0 0 5 5 5 1 Domain of unknown function (DUF4215) RRM_1 PF00076.22 EKX45851.1 - 1.3e-18 66.6 0.0 1.8e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EKX45851.1 - 0.0049 17.0 0.0 0.0075 16.4 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif Limkain-b1 PF11608.8 EKX45851.1 - 0.0086 16.1 0.1 0.024 14.7 0.1 1.7 1 1 0 1 1 1 1 Limkain b1 RRM_5 PF13893.6 EKX45851.1 - 0.1 12.2 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) THOC7 PF05615.13 EKX45852.1 - 2.2e-18 66.8 7.7 2.2e-18 66.8 7.7 1.9 1 1 1 2 2 2 1 Tho complex subunit 7 SEA PF01390.20 EKX45852.1 - 0.078 13.1 0.8 0.12 12.5 0.8 1.3 1 0 0 1 1 1 0 SEA domain Spore_IV_A PF09547.10 EKX45852.1 - 0.18 10.7 5.5 0.21 10.5 5.5 1.1 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) DUF4407 PF14362.6 EKX45852.1 - 0.71 9.2 7.9 0.79 9.0 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.11 EKX45852.1 - 0.81 10.3 9.5 0.1 13.2 2.8 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FUSC PF04632.12 EKX45852.1 - 1.1 7.8 7.3 1.2 7.6 7.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family FapA PF03961.13 EKX45852.1 - 1.1 7.8 9.6 1.2 7.6 9.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Musclin PF11037.8 EKX45852.1 - 1.3 9.0 6.0 0.7 9.8 1.8 2.0 1 1 1 2 2 2 0 Insulin-resistance promoting peptide in skeletal muscle OmpH PF03938.14 EKX45852.1 - 2.6 8.4 18.1 4.8 7.5 18.1 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.15 EKX45852.1 - 2.9 7.4 10.8 3.2 7.2 10.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 EKX45852.1 - 4.9 5.9 8.0 5.2 5.9 8.0 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4140 PF13600.6 EKX45852.1 - 8.9 6.8 11.3 2.4e+02 2.2 11.3 2.2 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) TMEM43 PF07787.12 EKX45853.1 - 0.053 12.9 8.1 0.021 14.2 5.2 1.7 1 1 1 2 2 2 0 Transmembrane protein 43 DUF962 PF06127.11 EKX45853.1 - 8.9 6.5 9.1 37 4.5 8.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF962) Ion_trans PF00520.31 EKX45855.1 - 1.1e-101 339.2 26.3 2.1e-35 122.1 0.9 5.7 4 2 0 4 4 4 4 Ion transport protein C2 PF00168.30 EKX45855.1 - 4.6e-12 46.1 0.0 9.3e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain fn2 PF00040.19 EKX45855.1 - 2.6e-09 37.2 3.0 6.2e-09 36.0 3.0 1.6 1 0 0 1 1 1 1 Fibronectin type II domain Med3 PF11593.8 EKX45856.1 - 0.11 11.7 0.3 0.15 11.2 0.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2774 PF11242.8 EKX45857.1 - 0.058 13.6 0.2 0.21 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) CENP-B_N PF04218.13 EKX45857.1 - 0.069 12.8 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain NAD_binding_10 PF13460.6 EKX45858.1 - 4.7e-11 42.9 0.1 1.4e-10 41.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H-binding Peptidase_S64 PF08192.11 EKX45858.1 - 1.8 7.0 13.4 2.8 6.3 13.4 1.2 1 0 0 1 1 1 0 Peptidase family S64 Ndc1_Nup PF09531.10 EKX45858.1 - 6.6 5.3 6.8 11 4.6 6.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1415 PF07209.12 EKX45859.1 - 8.8e-23 80.9 0.0 2.2e-22 79.6 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1415) DUF5463 PF17551.2 EKX45860.1 - 1.3 9.0 2.2 1.5e+02 2.4 0.1 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5463) UPF0225 PF17775.1 EKX45861.1 - 6.6e-16 58.9 0.0 8.9e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 UPF0225 domain SEC-C PF02810.15 EKX45861.1 - 0.0026 17.7 2.1 0.0043 16.9 2.1 1.4 1 0 0 1 1 1 1 SEC-C motif cobW PF02492.19 EKX45862.1 - 5.9e-44 149.7 0.0 1.3e-43 148.6 0.0 1.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EKX45862.1 - 2.1e-15 56.4 1.1 5.4e-15 55.1 0.3 2.1 3 0 0 3 3 2 1 Cobalamin synthesis protein cobW C-terminal domain T2SSE PF00437.20 EKX45862.1 - 0.00041 19.5 0.2 0.00071 18.7 0.2 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein MeaB PF03308.16 EKX45862.1 - 0.0016 17.5 0.0 0.0034 16.4 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 EKX45862.1 - 0.0034 17.0 0.1 0.024 14.2 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EKX45862.1 - 0.0034 17.8 1.2 0.0069 16.8 0.2 2.1 3 1 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 EKX45862.1 - 0.006 16.5 0.8 0.12 12.3 0.2 2.3 2 0 0 2 2 2 1 RsgA GTPase MobB PF03205.14 EKX45862.1 - 0.0081 16.1 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 EKX45862.1 - 0.013 15.8 0.4 0.039 14.2 0.1 1.9 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EKX45862.1 - 0.014 15.1 0.1 0.14 11.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EKX45862.1 - 0.02 14.8 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TsaE PF02367.17 EKX45862.1 - 0.024 14.7 0.1 0.053 13.5 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 EKX45862.1 - 0.045 12.9 0.1 0.094 11.9 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 EKX45862.1 - 0.056 13.5 0.2 0.26 11.3 0.0 2.2 3 0 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 EKX45862.1 - 0.066 12.9 0.1 0.099 12.4 0.1 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 EKX45862.1 - 0.067 13.4 0.1 0.16 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EKX45862.1 - 0.085 13.3 0.3 2 8.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EKX45862.1 - 0.086 12.6 0.3 0.18 11.5 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EKX45862.1 - 0.12 11.7 0.1 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.22 EKX45862.1 - 0.12 12.0 0.9 0.93 9.1 0.1 2.5 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 EKX45862.1 - 0.18 11.5 0.7 0.42 10.3 0.7 1.7 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein SAP PF02037.27 EKX45864.1 - 3.7e-11 42.5 3.1 3.7e-11 42.5 3.1 2.9 4 0 0 4 4 4 1 SAP domain DUF4250 PF14056.6 EKX45864.1 - 0.00049 20.0 0.0 65 3.6 0.0 6.7 7 0 0 7 7 7 0 Domain of unknown function (DUF4250) Laps PF10169.9 EKX45864.1 - 0.13 12.9 0.6 14 6.2 1.0 2.7 2 0 0 2 2 2 0 Learning-associated protein Zip PF02535.22 EKX45865.1 - 3.4e-09 36.4 11.3 3.4e-09 36.4 11.3 3.3 2 1 1 3 3 3 2 ZIP Zinc transporter Sel1 PF08238.12 EKX45866.1 - 0.013 16.1 0.1 2e+02 2.9 0.1 4.1 4 0 0 4 4 4 0 Sel1 repeat FANCI_S2 PF14676.6 EKX45867.1 - 4.1e-13 50.0 0.1 1.4e-12 48.3 0.1 2.0 1 0 0 1 1 1 1 FANCI solenoid 2 CobT PF06213.12 EKX45867.1 - 0.0001 21.8 21.3 0.00053 19.5 21.3 2.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT DDHD PF02862.17 EKX45867.1 - 0.00036 20.8 0.9 0.00079 19.6 0.9 1.5 1 0 0 1 1 1 1 DDHD domain RNA_pol_Rpc4 PF05132.14 EKX45867.1 - 0.00054 20.4 4.2 0.0017 18.8 4.2 1.8 1 0 0 1 1 1 1 RNA polymerase III RPC4 Spt20 PF12090.8 EKX45867.1 - 0.0019 17.9 20.9 0.0033 17.1 20.9 1.3 1 0 0 1 1 1 1 Spt20 family CDC45 PF02724.14 EKX45867.1 - 0.0073 14.7 10.6 0.013 13.8 10.6 1.4 1 0 0 1 1 1 1 CDC45-like protein DUF913 PF06025.12 EKX45867.1 - 0.0075 15.3 1.4 0.017 14.1 1.0 1.8 2 0 0 2 2 1 1 Domain of Unknown Function (DUF913) RRN3 PF05327.11 EKX45867.1 - 0.013 14.1 2.5 0.025 13.1 2.5 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TFIIA PF03153.13 EKX45867.1 - 0.016 15.2 17.1 0.026 14.5 17.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2457 PF10446.9 EKX45867.1 - 0.017 14.3 11.1 0.044 12.9 11.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Neur_chan_memb PF02932.16 EKX45867.1 - 0.021 14.9 1.5 0.046 13.8 1.5 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2828 PF11443.8 EKX45867.1 - 0.038 12.1 4.3 0.062 11.4 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) BORG_CEP PF14957.6 EKX45867.1 - 0.038 15.1 3.5 0.19 12.9 3.5 2.3 1 0 0 1 1 1 0 Cdc42 effector Plasmodium_Vir PF05795.11 EKX45867.1 - 0.12 11.7 6.5 0.3 10.4 6.5 1.6 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4820 PF16091.5 EKX45867.1 - 0.2 11.0 6.8 0.3 10.4 4.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) CPSF100_C PF13299.6 EKX45867.1 - 0.33 11.1 9.5 0.98 9.6 9.5 1.8 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF5308 PF17233.2 EKX45867.1 - 0.47 10.7 6.4 0.18 12.0 1.9 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5308) SpoIIP PF07454.11 EKX45867.1 - 0.71 9.3 15.6 1.3 8.5 15.6 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Lin-8 PF03353.15 EKX45867.1 - 0.97 8.9 15.7 1.7 8.1 15.7 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Band_3_cyto PF07565.13 EKX45867.1 - 1.1 9.0 5.5 2.9 7.6 5.5 1.7 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Peptidase_S64 PF08192.11 EKX45867.1 - 1.6 7.1 6.4 2.8 6.3 6.4 1.3 1 0 0 1 1 1 0 Peptidase family S64 Spore_coat_CotO PF14153.6 EKX45867.1 - 1.7 8.6 21.4 4.6 7.1 21.4 1.7 1 0 0 1 1 1 0 Spore coat protein CotO NPR3 PF03666.13 EKX45867.1 - 2 7.1 11.6 3.6 6.3 11.6 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Eapp_C PF10238.9 EKX45867.1 - 2.3 8.3 12.3 7.6 6.6 12.3 1.9 1 0 0 1 1 1 0 E2F-associated phosphoprotein ORC_WH_C PF18137.1 EKX45867.1 - 2.8 8.0 12.6 0.87 9.7 8.3 2.5 2 0 0 2 2 1 0 Origin recognition complex winged helix C-terminal SLC12 PF03522.15 EKX45867.1 - 3.8 6.4 10.0 6.6 5.6 10.0 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Connexin PF00029.19 EKX45867.1 - 5 6.8 13.2 7.1 6.3 11.9 1.8 2 0 0 2 2 2 0 Connexin Zip PF02535.22 EKX45867.1 - 6 6.0 7.1 13 4.9 7.1 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter DUF5327 PF17261.2 EKX45867.1 - 8.5 7.2 25.0 28 5.5 0.1 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5327) CTU2 PF10288.9 EKX45867.1 - 8.7 6.6 10.1 33 4.8 10.1 1.9 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Alpha_kinase PF02816.18 EKX45868.1 - 1.9e-32 112.9 0.1 5.4e-32 111.4 0.0 1.8 2 1 0 2 2 2 1 Alpha-kinase family Binary_toxB_3 PF17476.2 EKX45868.1 - 0.048 13.8 0.1 0.09 13.0 0.1 1.4 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA domain 3 PGM_PMM_I PF02878.16 EKX45869.1 - 4.2e-30 104.3 0.0 6.2e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EKX45869.1 - 2e-23 82.8 0.0 5.5e-23 81.3 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EKX45869.1 - 1.7e-07 31.8 0.0 8.8e-07 29.5 0.0 2.2 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EKX45869.1 - 7.3e-06 26.1 0.0 1.7e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain YbbR PF07949.12 EKX45869.1 - 0.074 13.4 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 YbbR-like protein TFIIB PF00382.19 EKX45871.1 - 9.6e-32 108.9 2.9 3.2e-15 55.9 0.3 3.0 2 1 1 3 3 3 3 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EKX45871.1 - 2.5e-12 46.1 3.8 7.2e-12 44.6 3.8 1.8 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 EKX45871.1 - 2.8e-05 23.9 0.2 0.15 11.8 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain OrfB_Zn_ribbon PF07282.11 EKX45871.1 - 0.0041 17.0 2.1 0.0083 16.0 2.1 1.5 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.10 EKX45871.1 - 1.1 9.4 4.1 13 6.0 0.5 2.5 2 0 0 2 2 2 0 Zinc ribbon domain TackOD1 PF18551.1 EKX45871.1 - 2.7 7.6 5.4 0.97 9.1 2.6 1.7 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 zf-ribbon_3 PF13248.6 EKX45871.1 - 2.8 7.5 9.1 1.2 8.6 4.7 2.5 2 1 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 EKX45871.1 - 4.8 7.2 5.6 38 4.3 5.6 2.3 1 1 0 1 1 1 0 zinc-ribbon domain F1F0-ATPsyn_F PF10791.9 EKX45872.1 - 0.00011 22.6 0.1 0.00013 22.4 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi CBP4 PF07960.11 EKX45874.1 - 0.0051 16.7 0.2 0.0075 16.1 0.2 1.2 1 0 0 1 1 1 1 CBP4 GSIII_N PF12437.8 EKX45875.1 - 1.4e-51 174.3 0.5 5.8e-51 172.3 0.0 2.3 3 0 0 3 3 3 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 EKX45875.1 - 3.7e-28 97.8 0.0 7.1e-28 96.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 EKX45875.1 - 1.1e-19 70.7 0.1 9.9e-19 67.5 0.0 2.2 3 0 0 3 3 3 1 Glutamine synthetase, catalytic domain Protoglobin PF11563.8 EKX45875.1 - 0.024 14.6 0.0 0.071 13.0 0.0 1.7 1 1 0 1 1 1 0 Protoglobin WD40 PF00400.32 EKX45876.1 - 1.3e-23 82.8 7.1 4.8e-07 30.4 0.1 6.5 4 1 1 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX45876.1 - 2.7e-11 43.6 0.0 7.2e-05 23.0 0.0 4.0 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 EKX45876.1 - 0.015 13.7 0.0 0.035 12.4 0.0 1.5 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 EKX45876.1 - 0.037 13.4 0.0 0.4 9.9 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain Cytochrom_D1 PF02239.16 EKX45876.1 - 0.042 12.4 0.1 9.9 4.6 0.0 2.8 2 1 1 3 3 3 0 Cytochrome D1 heme domain PFK PF00365.20 EKX45877.1 - 1.9e-62 211.2 0.1 3.4e-62 210.4 0.1 1.3 1 1 0 1 1 1 1 Phosphofructokinase DAGK_cat PF00781.24 EKX45877.1 - 0.0001 21.9 0.1 0.00027 20.5 0.1 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Pkinase PF00069.25 EKX45879.1 - 8.3e-59 199.1 0.0 9.7e-59 198.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX45879.1 - 2.8e-38 131.7 0.0 3.2e-38 131.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX45879.1 - 0.0005 19.5 0.1 0.0015 17.9 0.0 1.6 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EKX45879.1 - 0.0015 17.6 0.1 0.0017 17.3 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EKX45879.1 - 0.0025 17.5 0.5 0.11 12.0 0.0 2.2 1 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EKX45879.1 - 0.003 16.4 0.0 0.0054 15.6 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Nicastrin PF05450.15 EKX45879.1 - 0.19 11.1 0.1 0.74 9.2 0.0 2.0 1 1 1 3 3 3 0 Nicastrin Glyco_transf_5 PF08323.11 EKX45880.1 - 1.3e-56 192.1 0.0 1.8e-56 191.6 0.0 1.2 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EKX45880.1 - 1.8e-15 56.9 0.0 3.2e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EKX45880.1 - 6.1e-11 42.9 0.0 1.1e-10 42.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EKX45880.1 - 0.1 12.6 0.2 0.64 10.0 0.1 2.4 2 1 0 2 2 2 0 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EKX45880.1 - 0.11 12.9 0.1 1.6 9.2 0.2 2.6 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain Zn_clus PF00172.18 EKX45881.1 - 1.5e-05 25.0 11.5 3e-05 24.1 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 EKX45881.1 - 0.15 12.1 0.0 0.41 10.7 0.0 1.8 1 0 0 1 1 1 0 PAS fold SHIPPO-rpt PF07004.12 EKX45882.1 - 4.2 8.4 14.2 26 6.0 3.4 4.7 4 1 0 4 4 4 0 Sperm-tail PG-rich repeat kleA_kleC PF17383.2 EKX45883.1 - 0.045 14.1 1.0 0.098 13.0 1.0 1.5 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A Uso1_p115_C PF04871.13 EKX45883.1 - 0.052 13.9 3.8 0.059 13.8 3.8 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Arfaptin PF06456.13 EKX45883.1 - 0.052 13.1 0.1 0.064 12.8 0.1 1.0 1 0 0 1 1 1 0 Arfaptin-like domain BDV_P24 PF06595.11 EKX45883.1 - 0.059 13.3 0.1 0.069 13.0 0.1 1.0 1 0 0 1 1 1 0 Borna disease virus P24 protein DUF5082 PF16888.5 EKX45883.1 - 0.086 13.1 1.4 0.13 12.6 1.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF3040 PF11239.8 EKX45883.1 - 0.16 12.3 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DHR10 PF18595.1 EKX45883.1 - 0.23 11.6 5.1 0.39 10.8 5.1 1.6 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain MerR-DNA-bind PF09278.11 EKX45883.1 - 0.81 10.3 3.4 2.8 8.5 0.6 2.2 1 1 1 2 2 2 0 MerR, DNA binding UPF1_Zn_bind PF09416.10 EKX45884.1 - 2.1e-65 219.4 5.2 2.4e-64 215.9 2.3 2.5 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 EKX45884.1 - 1.2e-58 198.0 0.0 2.4e-58 197.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EKX45884.1 - 2.7e-49 168.3 3.0 3.4e-28 99.2 0.3 2.4 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 EKX45884.1 - 7.4e-28 96.6 0.0 2.5e-27 95.0 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 EKX45884.1 - 8.2e-13 48.5 0.2 8.5e-12 45.2 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EKX45884.1 - 4.6e-11 43.2 0.2 3.3e-10 40.5 0.3 2.3 2 1 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 EKX45884.1 - 2e-05 24.5 0.1 4.7e-05 23.3 0.1 1.7 1 0 0 1 1 1 1 Helicase DUF2075 PF09848.9 EKX45884.1 - 0.00027 20.3 4.2 0.0086 15.3 0.1 3.4 2 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 EKX45884.1 - 0.00032 20.8 0.1 0.00064 19.8 0.1 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EKX45884.1 - 0.02 14.3 0.1 0.097 12.1 0.0 2.0 1 1 1 2 2 2 0 PhoH-like protein PIF1 PF05970.14 EKX45884.1 - 0.027 13.6 0.1 3.5 6.7 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase ATPase PF06745.13 EKX45884.1 - 0.048 13.0 0.1 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_22 PF13401.6 EKX45884.1 - 0.1 12.9 0.1 0.24 11.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.15 EKX45884.1 - 0.14 11.3 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase tRNA-synt_1c PF00749.21 EKX45885.1 - 4e-103 344.6 0.0 5.2e-103 344.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EKX45885.1 - 1.3e-43 148.9 0.0 3.4e-43 147.5 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain Vfa1 PF08432.10 EKX45886.1 - 0.079 13.3 8.4 0.083 13.2 8.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Spt5_N PF11942.8 EKX45886.1 - 0.085 13.9 13.9 0.11 13.5 13.9 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal CENP-B_dimeris PF09026.10 EKX45886.1 - 0.18 12.2 11.5 0.23 11.8 11.5 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Connexin PF00029.19 EKX45886.1 - 0.32 10.7 2.4 0.37 10.5 2.4 1.0 1 0 0 1 1 1 0 Connexin FAM176 PF14851.6 EKX45886.1 - 0.45 10.2 7.6 0.56 9.9 7.6 1.3 1 0 0 1 1 1 0 FAM176 family DUF4637 PF15470.6 EKX45886.1 - 0.47 10.2 9.3 0.52 10.0 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) TFB6 PF17110.5 EKX45886.1 - 0.47 10.2 6.3 0.53 10.0 6.3 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH CDC45 PF02724.14 EKX45886.1 - 0.51 8.6 12.1 0.45 8.7 12.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 EKX45886.1 - 0.52 10.2 11.3 0.52 10.2 11.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CPSF100_C PF13299.6 EKX45886.1 - 0.55 10.4 6.6 0.58 10.3 6.6 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal GP67 PF17634.2 EKX45886.1 - 0.57 10.6 18.8 0.87 10.0 18.8 1.3 1 0 0 1 1 1 0 Gene product 67 PI3K_1B_p101 PF10486.9 EKX45886.1 - 0.78 7.4 7.0 0.84 7.3 7.0 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit GEN1_C PF18380.1 EKX45886.1 - 0.85 10.5 12.2 0.32 11.9 9.5 1.6 1 1 1 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain SDA1 PF05285.12 EKX45886.1 - 0.85 9.0 15.9 0.84 9.0 15.9 1.0 1 0 0 1 1 1 0 SDA1 AIF_C PF14721.6 EKX45886.1 - 1.5 9.2 5.1 1.8 8.9 5.1 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF2457 PF10446.9 EKX45886.1 - 1.7 7.7 19.8 1.8 7.6 19.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sporozoite_P67 PF05642.11 EKX45886.1 - 2.4 6.1 7.3 2.5 6.1 7.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 EKX45886.1 - 2.6 6.2 14.8 2.3 6.3 14.8 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EKX45886.1 - 2.6 6.0 16.3 2.4 6.1 16.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 EKX45886.1 - 3.3 6.1 11.9 3.5 6.1 11.9 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF913 PF06025.12 EKX45886.1 - 4.1 6.3 5.7 4.3 6.2 5.7 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RNA_pol_Rpc4 PF05132.14 EKX45886.1 - 4.4 7.7 5.8 5.4 7.4 5.8 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 Presenilin PF01080.17 EKX45886.1 - 9.2 4.9 5.2 8.3 5.1 5.2 1.0 1 0 0 1 1 1 0 Presenilin Ank_4 PF13637.6 EKX45887.1 - 5.3e-21 74.7 0.1 3.9e-12 46.4 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX45887.1 - 5.9e-15 55.6 0.2 7.3e-15 55.3 0.2 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX45887.1 - 3.5e-13 49.5 0.6 2.5e-05 24.5 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX45887.1 - 4.2e-10 39.6 0.4 8e-05 22.9 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EKX45887.1 - 4.3e-08 32.8 0.1 0.0014 18.9 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat DASH_Duo1 PF08651.10 EKX45888.1 - 0.0057 16.4 1.2 0.038 13.8 0.4 2.5 1 1 1 2 2 2 1 DASH complex subunit Duo1 Reticulon PF02453.17 EKX45888.1 - 0.11 12.5 1.8 0.5 10.3 0.5 2.3 1 1 1 2 2 2 0 Reticulon LRR_6 PF13516.6 EKX45890.1 - 2.6e-05 23.9 0.3 0.00039 20.3 0.2 2.1 2 0 0 2 2 2 1 Leucine Rich repeat Ligase_CoA PF00549.19 EKX45891.1 - 0.048 13.5 1.8 0.1 12.4 0.1 2.2 2 1 0 2 2 2 0 CoA-ligase DUF4140 PF13600.6 EKX45891.1 - 1.9 9.0 10.1 6.6 7.2 0.3 3.1 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Sec2p PF06428.11 EKX45891.1 - 3.7 7.6 14.1 0.2 11.7 1.2 3.4 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p HMG_box PF00505.19 EKX45892.1 - 3.6e-12 46.5 5.1 5.2e-09 36.4 0.7 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EKX45892.1 - 2.3e-09 37.7 6.9 8e-09 36.0 2.2 2.5 2 0 0 2 2 2 1 HMG-box domain zinc_ribbon_11 PF11682.8 EKX45892.1 - 0.0075 16.3 1.7 0.012 15.6 0.9 1.7 1 1 0 1 1 1 1 Probable zinc-ribbon INTS5_N PF14837.6 EKX45892.1 - 0.0098 15.5 0.2 0.015 14.9 0.2 1.2 1 0 0 1 1 1 1 Integrator complex subunit 5 N-terminus DZR PF12773.7 EKX45892.1 - 0.013 15.5 1.5 0.029 14.4 1.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon FAM195 PF14799.6 EKX45892.1 - 0.013 15.8 0.6 0.029 14.7 0.6 1.6 1 0 0 1 1 1 0 FAM195 family FYVE PF01363.21 EKX45892.1 - 0.025 14.7 3.1 0.034 14.3 2.0 1.7 2 0 0 2 2 2 0 FYVE zinc finger Nudix_N_2 PF14803.6 EKX45892.1 - 0.058 13.3 3.3 0.23 11.4 0.1 2.4 2 0 0 2 2 2 0 Nudix N-terminal TF_Zn_Ribbon PF08271.12 EKX45892.1 - 0.069 12.7 0.4 0.12 12.0 0.4 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding zinc_ribbon_2 PF13240.6 EKX45892.1 - 0.13 12.0 3.7 0.64 9.8 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DUF1289 PF06945.13 EKX45892.1 - 0.27 11.1 2.4 8.3 6.3 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) Lipase_3 PF01764.25 EKX45893.1 - 4.5e-12 46.0 0.0 2.6e-11 43.6 0.0 2.3 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EKX45893.1 - 4.9e-05 24.0 0.3 0.00014 22.6 0.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EKX45893.1 - 0.00012 22.3 0.5 0.00051 20.2 0.0 2.2 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_5 PF12695.7 EKX45893.1 - 0.039 13.7 0.1 0.074 12.8 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EKX45893.1 - 0.051 13.4 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 EKX45893.1 - 0.15 11.0 0.0 0.28 10.0 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme EF-hand_7 PF13499.6 EKX45895.1 - 2.3e-08 34.4 0.2 7.1e-06 26.4 0.2 2.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX45895.1 - 8.6e-08 31.5 0.5 0.043 13.8 0.1 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 EKX45895.1 - 1.9e-07 30.1 1.7 0.021 14.3 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 EKX45895.1 - 0.013 15.0 0.1 0.23 11.0 0.0 2.8 3 0 0 3 3 3 0 EF hand EF-hand_10 PF14788.6 EKX45895.1 - 0.028 14.3 1.8 1.9 8.4 0.0 2.9 3 0 0 3 3 3 0 EF hand Caleosin PF05042.13 EKX45895.1 - 0.1 12.5 0.6 2.9 7.8 0.0 2.2 2 0 0 2 2 2 0 Caleosin related protein COX6C PF02937.15 EKX45895.1 - 0.11 12.7 0.5 17 5.6 0.1 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIc TPPK_C PF12555.8 EKX45896.1 - 0.091 12.8 1.2 0.21 11.7 0.7 1.8 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal DSPc PF00782.20 EKX45897.1 - 1.8e-17 63.4 0.0 2.3e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX45897.1 - 3.5e-05 23.5 0.0 4.1e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EKX45897.1 - 0.001 19.1 0.0 0.0013 18.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family SOGA PF11365.8 EKX45898.1 - 0.00029 21.9 9.7 0.00052 21.1 9.7 1.4 1 0 0 1 1 1 1 Protein SOGA Zincin_1 PF06262.11 EKX45898.1 - 0.012 15.6 0.1 0.015 15.4 0.1 1.3 1 0 0 1 1 1 0 Zincin-like metallopeptidase OTCace PF00185.24 EKX45898.1 - 0.012 15.6 2.8 0.015 15.3 2.8 1.3 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF3584 PF12128.8 EKX45898.1 - 0.025 12.1 16.4 0.026 12.0 16.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 EKX45898.1 - 0.048 12.5 17.6 0.052 12.4 17.6 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein PilJ PF13675.6 EKX45898.1 - 0.051 13.6 1.2 0.063 13.3 1.2 1.3 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF948 PF06103.11 EKX45898.1 - 0.17 12.1 6.7 2.7 8.3 0.5 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) SKA2 PF16740.5 EKX45898.1 - 0.59 9.9 13.3 0.22 11.3 5.2 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Lipase PF00151.19 EKX45898.1 - 0.66 9.2 6.9 0.69 9.2 6.9 1.0 1 0 0 1 1 1 0 Lipase FapA PF03961.13 EKX45898.1 - 0.67 8.5 16.5 0.74 8.3 16.5 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A HIP1_clath_bdg PF16515.5 EKX45898.1 - 0.67 10.6 16.8 1.5 9.5 7.9 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF724 PF05266.14 EKX45898.1 - 1.2 8.9 19.0 0.3 10.9 8.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DIT1_PvcA PF05141.12 EKX45898.1 - 1.4 8.3 9.1 1.5 8.2 9.1 1.0 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein DUF1910 PF08928.10 EKX45898.1 - 3 7.9 13.7 3.6 7.6 5.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1910) UPF0242 PF06785.11 EKX45898.1 - 4.1 7.5 20.4 8.1 6.5 20.4 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 EKX45898.1 - 4.3 6.8 11.3 4.3 6.8 11.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 EKX45898.1 - 4.8 5.0 12.5 5.6 4.8 12.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family eIF-4B PF06273.11 EKX45898.1 - 6 5.8 11.1 6.4 5.7 11.1 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B PRKCSH-like PF12999.7 EKX45898.1 - 6.8 6.4 15.3 5.9 6.7 6.7 2.0 1 1 1 2 2 2 0 Glucosidase II beta subunit-like YabA PF06156.13 EKX45898.1 - 8.8 7.0 11.5 1.2e+02 3.3 11.5 2.1 1 1 0 1 1 1 0 Initiation control protein YabA LRR_8 PF13855.6 EKX45899.1 - 3.5e-36 122.8 29.9 1.1e-09 38.0 0.2 6.2 4 2 2 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 EKX45899.1 - 1.1e-33 114.7 44.7 7.8e-06 26.1 1.5 8.2 5 3 2 8 8 8 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX45899.1 - 1.1e-08 34.8 17.0 6.6e-06 25.7 1.3 4.2 1 1 2 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 EKX45899.1 - 2.6e-08 33.3 28.9 7.3 7.6 0.4 11.6 13 1 0 13 13 13 3 Leucine Rich Repeat LRR_6 PF13516.6 EKX45899.1 - 1.4e-05 24.7 23.3 2 8.7 0.4 8.6 9 0 0 9 9 9 3 Leucine Rich repeat Hydrolase_4 PF12146.8 EKX45900.1 - 1.3e-11 44.2 0.0 1.3e-06 27.9 0.0 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EKX45900.1 - 1.1e-07 31.8 0.2 1.6e-06 28.0 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.12 EKX45900.1 - 0.00073 18.3 0.0 0.071 11.8 0.0 2.3 2 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 EKX45900.1 - 0.00093 18.9 0.0 0.023 14.3 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 EKX45900.1 - 0.0012 19.6 0.0 0.0016 19.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 EKX45900.1 - 0.0052 16.5 0.0 0.012 15.2 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) CC2-LZ PF16516.5 EKX45901.1 - 0.0069 16.7 5.9 0.057 13.8 4.9 2.2 2 0 0 2 2 2 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator HELP PF03451.14 EKX45902.1 - 1.6e-09 37.5 0.0 2.2e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 HELP motif WD40 PF00400.32 EKX45902.1 - 1.4e-06 28.9 1.8 0.0065 17.3 0.1 2.7 2 1 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX45902.1 - 0.0017 18.6 1.1 0.023 15.0 0.6 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain zf-C3HC4 PF00097.25 EKX45903.1 - 2.4e-12 46.5 11.2 3.7e-12 45.9 11.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EKX45903.1 - 1.3e-10 40.9 8.4 2.2e-10 40.2 8.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX45903.1 - 3.1e-10 40.2 10.1 3.1e-10 40.2 10.1 1.5 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX45903.1 - 3.3e-10 39.6 10.0 5.9e-10 38.8 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EKX45903.1 - 8e-09 35.5 7.5 1.2e-08 34.9 7.5 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EKX45903.1 - 3e-08 33.6 9.6 5.4e-08 32.7 9.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EKX45903.1 - 3.2e-07 30.2 10.8 5.7e-07 29.4 10.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EKX45903.1 - 2.8e-06 27.1 10.1 5.3e-05 23.0 10.3 2.2 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EKX45903.1 - 1.6e-05 24.9 6.0 7.6e-05 22.7 6.0 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EKX45903.1 - 0.00015 22.0 11.2 0.00059 20.1 11.2 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 EKX45903.1 - 0.0062 16.3 5.7 0.01 15.6 5.7 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 EKX45903.1 - 0.013 15.3 6.0 0.03 14.1 6.0 1.7 1 0 0 1 1 1 0 RING-like zinc finger Rad50_zn_hook PF04423.14 EKX45903.1 - 0.013 15.3 3.0 0.56 10.1 0.8 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 EKX45903.1 - 0.018 14.8 8.9 0.018 14.8 8.9 2.1 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.7 EKX45903.1 - 0.13 12.3 7.1 1.2 9.3 7.1 2.2 1 1 1 2 2 2 0 Double zinc ribbon FYVE PF01363.21 EKX45903.1 - 0.18 12.0 10.6 0.57 10.4 10.6 1.9 1 1 0 1 1 1 0 FYVE zinc finger zinc-ribbons_6 PF07191.12 EKX45903.1 - 0.24 11.4 7.2 0.83 9.7 7.3 1.8 1 1 1 2 2 2 0 zinc-ribbons Zn_ribbon_17 PF17120.5 EKX45903.1 - 0.43 10.2 6.7 0.71 9.5 6.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EKX45903.1 - 0.56 10.4 9.3 5.8 7.2 9.3 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain Rtf2 PF04641.12 EKX45903.1 - 1 8.7 6.2 1.6 8.1 6.2 1.4 1 1 0 1 1 1 0 Rtf2 RING-finger Cys_rich_KTR PF14205.6 EKX45903.1 - 1.4 8.8 11.3 2.3 8.1 4.1 2.8 2 1 0 2 2 2 0 Cysteine-rich KTR zf-B_box PF00643.24 EKX45903.1 - 3 8.1 7.9 0.45 10.7 2.5 2.2 1 1 1 2 2 2 0 B-box zinc finger zf-C2H2_4 PF13894.6 EKX45903.1 - 7.6 7.7 8.0 7.9 7.6 0.6 3.0 2 1 1 3 3 3 0 C2H2-type zinc finger IBR PF01485.21 EKX45903.1 - 9.8 6.5 12.2 7.8 6.8 9.3 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Atx10homo_assoc PF09759.9 EKX45906.1 - 2.6e-25 88.3 4.5 1.6e-07 31.2 0.0 5.5 2 1 4 6 6 6 5 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 EKX45906.1 - 1.4e-22 79.0 0.0 3e-06 27.1 0.0 7.1 7 1 1 8 8 8 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EKX45906.1 - 4.4e-05 23.9 0.0 0.052 14.1 0.0 3.9 4 0 0 4 4 4 1 HEAT-like repeat Arm_2 PF04826.13 EKX45906.1 - 8.7e-05 22.1 0.7 0.072 12.5 0.0 3.4 1 1 1 3 3 3 1 Armadillo-like HEAT_2 PF13646.6 EKX45906.1 - 0.00092 19.6 0.2 0.093 13.1 0.1 3.2 1 1 2 3 3 3 2 HEAT repeats DUF1972 PF09314.11 EKX45906.1 - 0.061 12.9 0.7 28 4.2 0.0 3.7 4 1 1 5 5 5 0 Domain of unknown function (DUF1972) PUL PF08324.11 EKX45906.1 - 0.12 11.6 0.5 0.86 8.8 0.0 2.3 1 1 1 2 2 2 0 PUL domain HEAT PF02985.22 EKX45906.1 - 0.14 12.5 0.0 7.8 7.1 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat Methyltransf_10 PF05971.12 EKX45906.1 - 0.28 10.5 3.5 12 5.1 0.0 2.9 2 1 1 3 3 3 0 RNA methyltransferase SPT16 PF08644.11 EKX45906.1 - 2.9 8.1 5.2 24 5.1 0.3 2.5 1 1 1 2 2 2 0 FACT complex subunit (SPT16/CDC68) SET PF00856.28 EKX45907.1 - 1.6e-15 57.9 0.0 2.3e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 SET domain Romo1 PF10247.9 EKX45907.1 - 0.4 11.1 5.0 1.3 9.5 4.4 2.1 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 TTL PF03133.15 EKX45908.1 - 2.9e-46 157.9 0.0 3.5e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EKX45908.1 - 9.8e-05 21.7 0.0 0.0017 17.7 0.0 2.3 2 0 0 2 2 2 1 YheC/D like ATP-grasp DnaJ PF00226.31 EKX45909.1 - 5.5e-14 52.1 0.0 8.9e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF5075 PF16825.5 EKX45909.1 - 0.019 14.7 2.0 0.033 13.9 2.0 1.5 1 0 0 1 1 1 0 IGP family C-type lectin domain ELO PF01151.18 EKX45910.1 - 9.8e-48 162.9 25.9 1.4e-47 162.4 25.9 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF3176 PF11374.8 EKX45910.1 - 0.003 17.8 0.9 0.49 10.6 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3176) DUF4896 PF16237.5 EKX45910.1 - 4.5 7.2 7.7 7.1 6.6 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4896) Methyltransf_25 PF13649.6 EKX45911.1 - 2.6e-11 44.1 0.1 4.3e-11 43.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX45911.1 - 3.1e-10 40.5 0.0 4.6e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX45911.1 - 0.00063 20.4 0.0 0.0011 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EKX45911.1 - 0.003 17.1 0.0 0.0044 16.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EKX45911.1 - 0.014 15.2 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 EKX45911.1 - 0.14 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RRP36 PF06102.12 EKX45913.1 - 0.0028 17.6 10.9 0.0028 17.6 10.9 5.9 1 1 5 6 6 6 1 rRNA biogenesis protein RRP36 LPP PF04728.13 EKX45913.1 - 6.1 7.3 14.9 1.6 9.2 1.4 4.2 3 0 0 3 3 3 0 Lipoprotein leucine-zipper BK_channel_a PF03493.18 EKX45914.1 - 3.5e-29 100.9 0.0 9.5e-29 99.5 0.0 1.7 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 EKX45914.1 - 1.6e-18 66.8 10.6 2.7e-18 66.1 10.6 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX45914.1 - 2e-12 46.9 6.3 2e-12 46.9 6.3 2.5 2 1 0 2 2 2 1 Ion channel C2 PF00168.30 EKX45914.1 - 0.017 15.4 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 C2 domain IRK PF01007.20 EKX45914.1 - 0.058 13.2 0.8 2.4 8.0 0.1 2.5 2 0 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain RrnaAD PF00398.20 EKX45916.1 - 0.00091 18.4 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DUF938 PF06080.12 EKX45916.1 - 0.055 13.2 0.0 0.094 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.19 EKX45916.1 - 0.21 11.3 0.0 0.33 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CDC45 PF02724.14 EKX45917.1 - 0.0005 18.5 11.2 0.00054 18.4 11.2 1.2 1 0 0 1 1 1 1 CDC45-like protein FmiP_Thoc5 PF09766.9 EKX45917.1 - 0.00078 18.8 15.7 0.0011 18.3 15.7 1.2 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 Caldesmon PF02029.15 EKX45917.1 - 0.0054 15.6 29.5 0.006 15.4 29.5 1.1 1 0 0 1 1 1 1 Caldesmon Tim54 PF11711.8 EKX45917.1 - 0.016 14.0 13.0 0.023 13.5 13.0 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 MMR1 PF08505.10 EKX45917.1 - 0.033 14.5 19.8 0.045 14.0 19.8 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein eIF-3_zeta PF05091.12 EKX45917.1 - 0.072 12.1 25.4 0.11 11.4 25.4 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ndc1_Nup PF09531.10 EKX45917.1 - 0.083 11.6 6.0 0.13 10.9 6.0 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4045 PF13254.6 EKX45917.1 - 0.093 12.4 20.6 0.12 12.0 20.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SpoIIP PF07454.11 EKX45917.1 - 0.35 10.3 20.7 0.65 9.4 20.7 1.5 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Raftlin PF15250.6 EKX45917.1 - 0.65 8.7 17.9 0.91 8.2 17.9 1.2 1 0 0 1 1 1 0 Raftlin Plasmodium_Vir PF05795.11 EKX45917.1 - 3 7.1 14.9 4.3 6.7 14.9 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Gti1_Pac2 PF09729.9 EKX45917.1 - 3.3 7.8 17.1 5.8 7.0 17.1 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family CENP-N PF05238.13 EKX45917.1 - 5.5 6.2 14.9 7.2 5.8 14.9 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like NPR3 PF03666.13 EKX45917.1 - 8.3 5.1 29.1 0.048 12.4 20.7 1.5 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 SNARE_assoc PF09335.11 EKX45918.1 - 1.1e-19 71.1 13.3 2.8e-19 69.8 8.6 2.7 2 1 1 3 3 3 2 SNARE associated Golgi protein ExoD PF06055.12 EKX45918.1 - 5.4 6.4 13.0 0.2 11.0 2.9 2.6 3 0 0 3 3 3 0 Exopolysaccharide synthesis, ExoD Bcl-2_BAD PF10514.9 EKX45920.1 - 0.0056 17.2 1.0 0.0075 16.8 1.0 1.1 1 0 0 1 1 1 1 Pro-apoptotic Bcl-2 protein, BAD MDM10 PF12519.8 EKX45920.1 - 0.88 8.4 4.3 1.1 8.1 4.3 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 PTPRCAP PF15713.5 EKX45920.1 - 2.2 8.6 11.9 3.1 8.1 11.9 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Presenilin PF01080.17 EKX45920.1 - 5.5 5.6 7.2 6.1 5.5 7.2 1.0 1 0 0 1 1 1 0 Presenilin FAST_1 PF06743.15 EKX45921.1 - 2e-14 53.2 2.7 0.024 14.6 0.0 7.6 6 2 5 11 11 11 7 FAST kinase-like protein, subdomain 1 DUF1601 PF07671.11 EKX45921.1 - 1e-10 41.3 1.3 1.2 9.1 0.0 9.2 10 0 0 10 10 10 2 Protein of unknown function (DUF1601) PTPlike_phytase PF14566.6 EKX45922.1 - 0.015 15.4 0.1 0.015 15.4 0.1 1.0 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF1707 PF08044.11 EKX45923.1 - 0.13 12.4 6.8 7.2 6.8 0.3 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1707) Pkinase PF00069.25 EKX45924.1 - 1.2e-07 31.4 0.0 6.3e-06 25.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain DEP PF00610.21 EKX45924.1 - 0.17 12.0 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) TTL PF03133.15 EKX45925.1 - 1.4e-66 224.6 0.0 2.2e-66 224.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EKX45925.1 - 2.8e-09 36.6 0.0 6.3e-05 22.3 0.0 2.7 2 1 1 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EKX45925.1 - 7.1e-06 25.5 0.0 0.055 12.7 0.0 2.5 2 1 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EKX45925.1 - 0.0042 17.1 0.0 0.39 10.8 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain Kelch_4 PF13418.6 EKX45927.1 - 8.5e-36 121.7 0.6 2.6e-08 33.7 0.0 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 EKX45927.1 - 5.9e-29 99.8 2.3 4.1e-08 33.3 0.0 6.7 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 EKX45927.1 - 9.4e-26 89.2 6.2 1e-07 31.9 0.1 5.8 5 1 1 6 6 6 5 Kelch motif Kelch_5 PF13854.6 EKX45927.1 - 6.7e-25 86.6 0.1 1.4e-07 31.3 0.0 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 EKX45927.1 - 7.8e-17 60.5 2.8 1.9e-05 24.5 0.0 6.2 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 EKX45927.1 - 9.8e-16 57.1 0.5 8.1e-05 22.1 0.0 6.2 6 1 0 6 6 6 3 Kelch motif HTH_21 PF13276.6 EKX45927.1 - 0.06 13.5 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 HTH-like domain Myb_DNA-binding PF00249.31 EKX45928.1 - 7.9e-12 45.2 0.0 1.9e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EKX45928.1 - 0.00049 19.9 0.1 0.00092 19.1 0.1 1.4 1 0 0 1 1 1 1 Myb DNA-binding like Cep57_CLD_2 PF14197.6 EKX45928.1 - 0.0079 16.3 1.2 0.018 15.1 1.2 1.5 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 Myb_DNA-bind_6 PF13921.6 EKX45928.1 - 0.016 15.5 1.0 0.023 14.9 0.1 1.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain MCR PF18509.1 EKX45929.1 - 0.057 13.0 0.6 0.057 13.0 0.6 5.1 6 0 0 6 6 6 0 Magnetochrome domain MAR_sialic_bdg PF10564.9 EKX45930.1 - 0.00054 19.9 0.3 0.0017 18.3 0.3 1.9 1 0 0 1 1 1 1 Sialic-acid binding micronemal adhesive repeat DUF1664 PF07889.12 EKX45930.1 - 0.045 13.8 25.2 0.064 13.3 4.1 3.8 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) RPAP1_C PF08620.10 EKX45930.1 - 0.13 12.4 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 RPAP1-like, C-terminal RskA PF10099.9 EKX45930.1 - 0.24 11.7 6.4 3 8.1 4.3 2.6 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Mst1_SARAH PF11629.8 EKX45930.1 - 0.3 11.2 2.8 0.82 9.8 0.1 2.9 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 Plasmid_RAQPRD PF09686.10 EKX45930.1 - 0.42 10.9 4.6 0.45 10.7 0.9 2.9 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) HrpB7 PF09486.10 EKX45930.1 - 4.3 7.7 15.2 2.2 8.6 5.1 3.8 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) CorA PF01544.18 EKX45930.1 - 5.4 6.3 11.4 5 6.3 2.4 2.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 EKX45930.1 - 7.4 6.6 20.2 12 5.9 8.5 3.6 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC_membrane_2 PF06472.15 EKX45932.1 - 3.9e-50 170.8 1.9 1.2e-48 165.8 1.9 2.0 1 1 0 1 1 1 1 ABC transporter transmembrane region 2 Acyltransf_C PF16076.5 EKX45932.1 - 0.017 15.2 0.1 0.054 13.6 0.1 1.9 2 0 0 2 2 2 0 Acyltransferase C-terminus TMEM43 PF07787.12 EKX45932.1 - 0.065 12.6 0.5 0.13 11.7 0.5 1.4 1 0 0 1 1 1 0 Transmembrane protein 43 G-patch_2 PF12656.7 EKX45933.1 - 1.9e-19 69.5 0.5 1.9e-19 69.5 0.5 2.7 2 0 0 2 2 2 1 G-patch domain G-patch PF01585.23 EKX45933.1 - 4.2e-10 39.4 1.3 1.1e-09 38.0 1.3 1.8 1 0 0 1 1 1 1 G-patch domain KN17_SH3 PF18131.1 EKX45933.1 - 4e-07 30.1 4.0 4.8e-07 29.8 0.5 2.9 3 0 0 3 3 3 1 KN17 SH3-like C-terminal domain KOW PF00467.29 EKX45933.1 - 0.00025 20.9 6.1 0.058 13.4 0.0 3.3 3 0 0 3 3 3 2 KOW motif PIEZO PF15917.5 EKX45933.1 - 0.0013 18.3 6.4 0.0035 16.9 6.4 1.7 1 0 0 1 1 1 1 Piezo SH3_3 PF08239.11 EKX45933.1 - 0.085 13.2 0.3 23 5.4 0.1 2.9 2 0 0 2 2 2 0 Bacterial SH3 domain Zip PF02535.22 EKX45933.1 - 0.39 9.9 1.0 0.66 9.1 1.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 EKX45933.1 - 1.3 9.1 5.8 0.13 12.2 0.7 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SBDS PF01172.18 EKX45934.1 - 1.1e-16 60.7 0.0 1.7e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 EKX45934.1 - 7.3e-06 26.0 0.3 3.2e-05 23.9 0.1 2.0 2 0 0 2 2 2 1 SBDS protein C-terminal domain CDT1_C PF16679.5 EKX45934.1 - 0.0047 17.3 2.2 0.0088 16.5 2.0 1.6 1 1 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain DUF5101 PF17031.5 EKX45934.1 - 0.018 15.2 0.9 0.069 13.3 1.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5101) PAP_fibrillin PF04755.12 EKX45935.1 - 2e-12 47.5 0.1 3.3e-12 46.8 0.1 1.4 1 0 0 1 1 1 1 PAP_fibrillin tRNA_int_end_N2 PF12928.7 EKX45935.1 - 0.048 13.8 0.1 0.092 12.9 0.1 1.5 1 0 0 1 1 1 0 tRNA-splicing endonuclease subunit sen54 N-term Thioredoxin PF00085.20 EKX45937.1 - 3.7e-18 65.4 0.6 2.8e-11 43.3 0.1 2.8 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EKX45937.1 - 6.4e-15 55.5 1.9 0.00012 22.1 0.1 3.9 3 1 1 4 4 4 4 Thioredoxin-like domain HyaE PF07449.11 EKX45937.1 - 0.026 14.5 0.0 2.3 8.2 0.0 3.0 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 EKX45937.1 - 0.035 14.4 1.2 12 6.3 0.1 3.2 3 1 0 3 3 3 0 Thioredoxin-like PABP PF00658.18 EKX45938.1 - 1.9e-10 40.7 0.0 3.1e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain SLBP_RNA_bind PF15247.6 EKX45938.1 - 6.1e-08 32.7 0.8 1.1e-05 25.4 0.3 3.5 5 0 0 5 5 5 2 Histone RNA hairpin-binding protein RNA-binding domain Toxin_29 PF08116.11 EKX45939.1 - 0.12 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 PhTx neurotoxin family Methyltransf_11 PF08241.12 EKX45940.1 - 3.5e-25 88.5 0.0 5.4e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX45940.1 - 3.2e-23 82.3 0.0 5.3e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EKX45940.1 - 6.1e-21 74.9 0.0 7e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 EKX45940.1 - 2.7e-17 63.0 0.0 3.6e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX45940.1 - 2.9e-15 56.5 0.0 4e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX45940.1 - 2.2e-14 54.0 0.0 3.6e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX45940.1 - 9.4e-12 44.8 0.0 1.4e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EKX45940.1 - 0.00013 21.8 0.0 0.00018 21.3 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EKX45940.1 - 0.00014 21.9 0.0 0.0002 21.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 EKX45940.1 - 0.00016 21.3 0.0 0.00024 20.7 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase MTS PF05175.14 EKX45940.1 - 0.00034 20.2 0.0 0.00057 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_29 PF03141.16 EKX45940.1 - 0.00051 18.7 0.0 0.00066 18.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.18 EKX45940.1 - 0.0018 17.6 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_9 PF08003.11 EKX45940.1 - 0.0026 16.7 0.0 0.0046 15.9 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) FtsJ PF01728.19 EKX45940.1 - 0.0043 17.2 0.0 0.1 12.7 0.0 2.1 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_8 PF05148.15 EKX45940.1 - 0.0043 16.9 0.0 0.011 15.6 0.0 1.7 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_15 PF09445.10 EKX45940.1 - 0.01 15.4 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 EKX45940.1 - 0.019 14.7 0.0 0.14 11.8 0.0 1.9 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 PrmA PF06325.13 EKX45940.1 - 0.033 13.6 0.0 0.066 12.6 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) ADH_zinc_N PF00107.26 EKX45940.1 - 0.08 12.9 0.0 0.28 11.2 0.0 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase TPMT PF05724.11 EKX45940.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Ras PF00071.22 EKX45943.1 - 1.4e-46 158.1 1.8 1.4e-46 158.1 1.8 1.4 2 0 0 2 2 2 1 Ras family Roc PF08477.13 EKX45943.1 - 2.6e-33 114.8 0.5 2.6e-33 114.8 0.5 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EKX45943.1 - 1.3e-12 47.5 0.4 2e-12 46.9 0.4 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EKX45943.1 - 1.8e-07 31.2 0.3 0.0052 16.7 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EKX45943.1 - 1.2e-06 28.5 1.0 2.2e-06 27.7 0.1 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EKX45943.1 - 0.00086 18.9 5.4 0.0036 16.9 5.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EKX45943.1 - 0.0015 17.9 0.1 0.003 16.9 0.1 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 EKX45943.1 - 0.0024 17.7 6.1 0.0039 17.0 0.3 2.6 1 1 1 3 3 3 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 EKX45943.1 - 0.005 16.4 0.4 2.7 7.5 0.2 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 EKX45943.1 - 0.0083 16.1 0.7 0.032 14.2 0.6 2.1 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Septin PF00735.18 EKX45943.1 - 0.018 14.4 0.0 0.018 14.4 0.0 1.9 3 0 0 3 3 3 0 Septin AAA_16 PF13191.6 EKX45943.1 - 0.035 14.5 0.0 0.068 13.5 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain HGTP_anticodon2 PF12745.7 EKX45943.1 - 0.048 13.2 8.9 0.072 12.6 8.9 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Dmrt1 PF12374.8 EKX45943.1 - 0.1 13.0 1.7 0.19 12.2 1.7 1.4 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 ABC_tran PF00005.27 EKX45943.1 - 4.7 7.7 9.1 1e+02 3.4 9.1 2.3 1 1 0 1 1 1 0 ABC transporter DDHD PF02862.17 EKX45944.1 - 0.00075 19.7 4.2 0.00075 19.7 4.2 1.2 1 0 0 1 1 1 1 DDHD domain TFIIA PF03153.13 EKX45944.1 - 0.0025 17.9 33.4 0.0025 17.9 33.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit C2 PF00168.30 EKX45944.1 - 0.0029 17.9 0.0 0.0059 16.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF5308 PF17233.2 EKX45944.1 - 0.0051 17.1 4.3 0.0051 17.1 4.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5308) EPL1 PF10513.9 EKX45944.1 - 0.043 14.2 11.3 0.048 14.1 11.3 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF4638 PF15472.6 EKX45944.1 - 0.093 12.5 10.1 0.11 12.2 10.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Lin-8 PF03353.15 EKX45944.1 - 0.097 12.2 14.8 0.11 12.1 14.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 EKX45944.1 - 0.1 11.3 14.3 0.11 11.3 14.3 1.1 1 0 0 1 1 1 0 Presenilin ABC2_membrane_2 PF12679.7 EKX45944.1 - 0.11 11.7 1.7 0.1 11.8 1.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein PAT1 PF09770.9 EKX45944.1 - 0.13 10.6 23.1 0.12 10.6 23.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SpoIIP PF07454.11 EKX45944.1 - 0.15 11.5 14.8 0.16 11.4 14.8 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF913 PF06025.12 EKX45944.1 - 0.18 10.8 6.9 0.2 10.6 6.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4175 PF13779.6 EKX45944.1 - 0.25 9.2 43.1 0.27 9.1 43.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) GREB1 PF15782.5 EKX45944.1 - 0.27 8.3 8.9 0.22 8.6 8.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PepSY_TM PF03929.16 EKX45944.1 - 0.4 10.3 6.2 0.39 10.3 6.2 1.2 1 0 0 1 1 1 0 PepSY-associated TM region SLC12 PF03522.15 EKX45944.1 - 0.63 9.0 12.7 0.64 9.0 12.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Rxt3 PF08642.10 EKX45944.1 - 0.67 10.7 6.2 0.88 10.3 6.2 1.4 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 MMR1 PF08505.10 EKX45944.1 - 0.73 10.1 16.3 0.78 10.0 16.3 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF4407 PF14362.6 EKX45944.1 - 0.77 9.1 15.6 0.78 9.0 15.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GvpL_GvpF PF06386.11 EKX45944.1 - 0.95 9.3 10.9 1.1 9.2 10.9 1.1 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF MDM10 PF12519.8 EKX45944.1 - 1.2 7.9 12.1 1.3 7.8 12.1 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 GNT-I PF03071.15 EKX45944.1 - 1.4 7.6 11.8 1.7 7.3 11.8 1.1 1 0 0 1 1 1 0 GNT-I family Plasmodium_Vir PF05795.11 EKX45944.1 - 1.4 8.3 4.3 1.3 8.3 4.3 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Gti1_Pac2 PF09729.9 EKX45944.1 - 1.5 8.9 11.5 1.8 8.6 11.5 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Eapp_C PF10238.9 EKX45944.1 - 1.5 8.9 16.1 1.9 8.6 16.1 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein Otopetrin PF03189.13 EKX45944.1 - 1.9 7.2 5.7 1.8 7.3 5.7 1.1 1 0 0 1 1 1 0 Otopetrin Ndc1_Nup PF09531.10 EKX45944.1 - 1.9 7.1 10.5 1.9 7.1 10.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Band_3_cyto PF07565.13 EKX45944.1 - 2.6 7.8 13.8 3 7.6 13.8 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FAM91_C PF14648.6 EKX45944.1 - 2.7 6.7 8.8 3.2 6.5 8.8 1.2 1 0 0 1 1 1 0 FAM91 C-terminus DUF4770 PF15994.5 EKX45944.1 - 2.9 8.1 16.9 3.6 7.8 16.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) NPR3 PF03666.13 EKX45944.1 - 3 6.5 12.9 3.4 6.4 12.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Bud13 PF09736.9 EKX45944.1 - 3.6 8.0 19.9 4.4 7.7 19.9 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex eIF-3_zeta PF05091.12 EKX45944.1 - 4 6.3 25.8 4.9 6.0 25.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FAM60A PF15396.6 EKX45944.1 - 4.8 7.1 11.6 6 6.8 11.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A FAM222A PF15258.6 EKX45944.1 - 5 6.1 23.3 5.1 6.1 23.3 1.2 1 0 0 1 1 1 0 Protein family of FAM222A Pal1 PF08316.11 EKX45944.1 - 5.6 7.7 6.8 19 6.0 7.6 1.6 2 0 0 2 2 1 0 Pal1 cell morphology protein Tim54 PF11711.8 EKX45944.1 - 5.9 5.6 15.5 7.5 5.2 15.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FAM150 PF15129.6 EKX45944.1 - 6.6 6.9 15.1 8.8 6.5 15.1 1.2 1 0 0 1 1 1 0 FAM150 family Sec62 PF03839.16 EKX45944.1 - 6.6 6.2 11.4 7.7 5.9 11.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 UPF0560 PF10577.9 EKX45944.1 - 6.7 5.1 24.9 7.9 4.8 24.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 CPSF100_C PF13299.6 EKX45944.1 - 7.4 6.7 15.8 12 6.1 15.8 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal ALMT PF11744.8 EKX45944.1 - 7.5 5.3 11.3 8.1 5.2 11.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter CDC45 PF02724.14 EKX45944.1 - 8.1 4.6 13.0 8.7 4.5 13.0 1.1 1 0 0 1 1 1 0 CDC45-like protein PRC2_HTH_1 PF18118.1 EKX45944.1 - 8.1 7.3 12.2 13 6.7 12.2 1.4 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain DUF5523 PF17661.1 EKX45944.1 - 8.2 6.0 20.5 10 5.7 20.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Spc24 PF08286.11 EKX45945.1 - 0.029 14.6 0.6 0.074 13.3 0.6 1.7 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Mnd1 PF03962.15 EKX45945.1 - 0.13 12.6 0.3 0.3 11.4 0.3 1.6 1 0 0 1 1 1 0 Mnd1 HTH domain Selenoprotein_S PF06936.11 EKX45946.1 - 1.1e-05 25.4 12.4 4e-05 23.5 12.3 1.9 1 1 0 1 1 1 1 Selenoprotein S (SelS) U79_P34 PF03064.16 EKX45946.1 - 0.0027 17.1 1.1 0.0029 17.0 1.1 1.1 1 0 0 1 1 1 1 HSV U79 / HCMV P34 Histone_HNS PF00816.21 EKX45946.1 - 0.0081 17.0 2.4 0.018 15.8 2.4 1.6 1 0 0 1 1 1 1 H-NS histone family Zip PF02535.22 EKX45946.1 - 0.19 10.9 0.1 0.2 10.8 0.1 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Pam16 PF03656.13 EKX45947.1 - 6.9e-18 64.9 1.1 9.6e-18 64.4 1.1 1.1 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 EKX45947.1 - 0.0038 17.3 0.1 0.0076 16.3 0.1 1.5 1 1 0 1 1 1 1 DnaJ domain PQ-loop PF04193.14 EKX45948.1 - 2e-07 30.6 3.1 2e-07 30.6 3.1 1.9 2 0 0 2 2 2 1 PQ loop repeat MtN3_slv PF03083.16 EKX45948.1 - 0.027 14.5 1.5 0.34 11.0 0.5 2.2 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange ODV-E18 PF10717.9 EKX45948.1 - 0.077 12.9 0.5 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Homeobox_KN PF05920.11 EKX45949.1 - 9.5e-17 60.6 0.0 1.3e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EKX45949.1 - 3.1e-10 39.7 0.0 3.6e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 EKX45949.1 - 0.0031 16.9 0.5 0.028 13.9 0.4 1.9 1 1 1 2 2 2 1 Homeodomain leucine-zipper encoding, Homez Mito_carr PF00153.27 EKX45950.1 - 1.2e-35 121.3 0.1 4e-10 39.5 0.1 5.4 4 1 1 5 5 5 5 Mitochondrial carrier protein TraB PF01963.17 EKX45950.1 - 0.48 10.3 7.0 0.88 9.4 7.0 1.4 1 0 0 1 1 1 0 TraB family PilJ PF13675.6 EKX45950.1 - 2 8.5 7.6 40 4.3 1.7 3.6 2 2 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Baculo_PEP_C PF04513.12 EKX45950.1 - 2.1 8.4 3.8 1.9 8.5 0.3 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus adh_short PF00106.25 EKX45951.1 - 9.3e-19 67.6 0.0 1e-18 67.5 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EKX45951.1 - 7.9e-09 35.7 0.1 8.4e-09 35.6 0.1 1.0 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EKX45951.1 - 1.6e-07 31.1 0.0 1.8e-07 31.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EKX45951.1 - 0.0016 18.0 0.0 0.0017 17.8 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EKX45951.1 - 0.051 12.7 0.0 0.057 12.6 0.0 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Bac_rhodopsin PF01036.18 EKX45953.1 - 0.00046 19.8 3.2 0.00066 19.3 3.2 1.2 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF2269 PF10027.9 EKX45953.1 - 0.12 12.4 3.1 0.38 10.8 1.7 2.2 2 1 0 2 2 2 0 Predicted integral membrane protein (DUF2269) DUF4131 PF13567.6 EKX45953.1 - 1.2 8.8 3.9 5.7 6.6 2.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) HEAT PF02985.22 EKX45954.1 - 1.4 9.3 12.1 9.4 6.8 0.0 5.2 5 0 0 5 5 5 0 HEAT repeat Ank_5 PF13857.6 EKX45955.1 - 1.3e-18 66.7 7.8 2.1e-08 34.3 0.4 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX45955.1 - 5.5e-18 64.5 1.6 3.2e-06 27.3 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EKX45955.1 - 2.1e-17 63.5 0.0 2.6e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX45955.1 - 1.2e-13 49.9 0.5 0.0039 17.6 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EKX45955.1 - 1.6e-12 47.6 1.2 1.2e-06 29.0 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) SelR PF01641.18 EKX45956.1 - 6.2e-05 23.1 0.3 0.00025 21.1 0.3 1.9 1 1 0 1 1 1 1 SelR domain RWP-RK PF02042.15 EKX45957.1 - 4.8e-15 55.3 0.2 7.9e-15 54.6 0.2 1.4 1 0 0 1 1 1 1 RWP-RK domain Sigma70_r4_2 PF08281.12 EKX45957.1 - 0.075 12.7 0.1 0.51 10.0 0.1 2.1 1 1 0 1 1 1 0 Sigma-70, region 4 RWP-RK PF02042.15 EKX45958.1 - 3.4e-15 55.8 0.2 6.6e-15 54.8 0.2 1.5 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX45958.1 - 0.16 11.8 0.3 1.2 9.0 0.1 2.2 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family P16-Arc PF04699.14 EKX45959.1 - 4.3e-31 108.4 0.1 4.6e-31 108.3 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) PX PF00787.24 EKX45961.1 - 5.2e-11 42.5 1.1 1.3e-10 41.2 0.1 2.2 2 0 0 2 2 2 1 PX domain GBP PF02263.19 EKX45961.1 - 1.5e-07 31.0 1.8 1.8e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain Caveolin PF01146.17 EKX45961.1 - 0.11 12.5 0.1 3.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Caveolin FlaA PF04620.12 EKX45962.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Flagellar filament outer layer protein Flaa Actin PF00022.19 EKX45963.1 - 1.7e-27 96.1 0.0 3.7e-26 91.7 0.0 2.6 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EKX45963.1 - 0.00063 18.6 0.7 0.33 9.7 0.1 2.3 2 0 0 2 2 2 2 MreB/Mbl protein PilM_2 PF11104.8 EKX45963.1 - 0.00075 18.6 0.1 0.22 10.5 0.0 2.3 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; FtsA PF14450.6 EKX45963.1 - 0.002 18.5 0.2 0.074 13.5 0.1 2.5 2 0 0 2 2 2 1 Cell division protein FtsA Actin_micro PF17003.5 EKX45963.1 - 0.024 13.8 0.2 0.13 11.4 0.0 2.1 2 0 0 2 2 2 0 Putative actin-like family CDC45 PF02724.14 EKX45963.1 - 0.95 7.7 9.5 1.3 7.2 9.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Merozoite_SPAM PF07133.11 EKX45963.1 - 2.5 8.1 22.7 4.1 7.3 22.7 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) polyprenyl_synt PF00348.17 EKX45964.1 - 5.9e-21 74.7 0.2 9e-21 74.1 0.2 1.4 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 EKX45964.1 - 0.00072 19.2 0.0 0.002 17.8 0.0 1.7 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 DUF4875 PF16175.5 EKX45964.1 - 0.062 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4875) CRAL_TRIO PF00650.20 EKX45967.1 - 3.6e-28 98.3 0.1 8e-28 97.2 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EKX45967.1 - 0.0023 18.1 0.0 0.0057 16.8 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain LysM PF01476.20 EKX45968.1 - 0.0017 18.4 0.0 0.2 11.8 0.0 2.8 2 0 0 2 2 2 2 LysM domain SK_channel PF03530.14 EKX45969.1 - 0.0014 18.6 4.0 0.0014 18.6 4.0 3.6 3 2 1 4 4 4 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.16 EKX45969.1 - 0.0028 17.6 0.5 0.0028 17.6 0.5 3.3 4 0 0 4 4 4 1 Ion channel DUF4006 PF13179.6 EKX45969.1 - 0.16 11.9 1.5 3.5 7.6 0.6 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF4006) SLX9 PF15341.6 EKX45969.1 - 1.3 9.5 7.5 0.29 11.5 1.4 2.4 2 1 0 2 2 2 0 Ribosome biogenesis protein SLX9 AAA_6 PF12774.7 EKX45970.1 - 2.2e-148 493.6 0.0 2.1e-146 487.0 0.0 3.1 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EKX45970.1 - 1.4e-131 439.3 0.6 1.4e-131 439.3 0.6 2.7 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 EKX45970.1 - 3.5e-106 354.9 0.0 5.6e-105 350.9 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 EKX45970.1 - 1.1e-98 329.8 0.0 2.3e-98 328.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EKX45970.1 - 1.4e-89 299.0 0.0 4.9e-88 293.9 0.1 3.0 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 EKX45970.1 - 1.9e-75 252.4 0.4 3.6e-73 244.9 0.0 3.0 3 0 0 3 3 2 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EKX45970.1 - 2.6e-55 186.7 0.0 8e-55 185.1 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 EKX45970.1 - 8.6e-55 186.1 13.0 1.4e-54 185.4 13.0 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EKX45970.1 - 4e-45 152.7 0.0 1.1e-41 141.7 0.0 3.0 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EKX45970.1 - 2.4e-27 95.6 1.1 1.2e-26 93.3 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EKX45970.1 - 1.3e-22 79.9 0.0 4.5e-22 78.1 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EKX45970.1 - 2.4e-11 43.8 0.0 0.018 15.0 0.0 5.7 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA PF00004.29 EKX45970.1 - 3.3e-05 24.3 0.1 0.16 12.4 0.0 3.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX45970.1 - 0.00052 20.4 0.0 4.3 7.7 0.0 4.4 3 0 0 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.22 EKX45970.1 - 0.0047 17.3 0.0 4.5 7.7 0.0 3.1 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 EKX45970.1 - 0.0068 17.0 0.0 2.1 8.9 0.0 3.8 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 EKX45970.1 - 0.0079 15.9 0.0 0.6 9.8 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 EKX45970.1 - 0.0096 16.2 0.2 2.1 8.6 0.0 3.5 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.13 EKX45970.1 - 0.018 14.2 0.5 0.64 9.1 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF815) Arteri_nsp7a PF16749.5 EKX45970.1 - 0.094 12.9 0.3 0.33 11.1 0.3 1.9 1 0 0 1 1 1 0 Arterivirus nonstructural protein 7 alpha RNase_H2-Ydr279 PF09468.10 EKX45970.1 - 4.1 7.6 7.4 6.3 7.0 0.8 3.4 4 0 0 4 4 2 0 Ydr279p protein family (RNase H2 complex component) wHTH domain DUF4407 PF14362.6 EKX45970.1 - 8.4 5.7 9.3 0.9 8.8 2.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SAP PF02037.27 EKX45971.1 - 7.2e-05 22.4 0.4 0.00067 19.4 0.0 2.6 3 0 0 3 3 3 1 SAP domain RNA_pol_Rpb1_7 PF04990.12 EKX45971.1 - 0.11 12.4 0.8 0.21 11.6 0.8 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 7 TRAPP PF04051.16 EKX45972.1 - 7.2e-35 119.8 0.0 8.5e-35 119.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DEAD PF00270.29 EKX45973.1 - 1.5e-41 142.0 0.1 2.3e-41 141.5 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX45973.1 - 9.4e-22 77.5 0.0 3.7e-21 75.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX45973.1 - 1.9e-05 24.8 0.0 3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EKX45973.1 - 0.0033 16.8 0.1 0.0051 16.2 0.1 1.2 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit SecA_DEAD PF07517.14 EKX45973.1 - 0.1 11.9 0.1 7.4 5.8 0.0 2.6 3 0 0 3 3 3 0 SecA DEAD-like domain Ax_dynein_light PF10211.9 EKX45974.1 - 1.1e-73 247.2 10.9 1.4e-73 246.8 10.9 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain GIT_CC PF16559.5 EKX45974.1 - 0.011 15.6 2.2 0.027 14.3 2.2 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.15 EKX45974.1 - 0.046 13.5 4.5 0.052 13.3 2.3 2.2 1 1 1 2 2 2 0 Septum formation initiator YabA PF06156.13 EKX45974.1 - 0.081 13.6 5.3 0.12 13.0 3.5 2.2 2 0 0 2 2 2 0 Initiation control protein YabA FeoB_Cyto PF17910.1 EKX45974.1 - 0.1 13.2 3.3 0.14 12.7 1.3 2.1 2 0 0 2 2 2 0 FeoB cytosolic helical domain TMPIT PF07851.13 EKX45974.1 - 0.39 9.9 4.7 0.61 9.3 4.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein PI3K_P85_iSH2 PF16454.5 EKX45974.1 - 0.49 10.0 12.3 0.11 12.1 9.1 1.6 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TSC22 PF01166.18 EKX45974.1 - 0.75 10.1 7.5 0.99 9.8 2.7 3.1 3 1 1 4 4 4 0 TSC-22/dip/bun family ZapB PF06005.12 EKX45974.1 - 1.7 9.1 12.6 28 5.2 12.8 2.7 1 1 1 2 2 2 0 Cell division protein ZapB DUF724 PF05266.14 EKX45974.1 - 6.3 6.6 11.0 2.4 8.0 8.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) CALM_bind PF16025.5 EKX45974.1 - 8.2 7.0 11.6 0.14 12.6 3.4 2.3 3 1 0 3 3 2 0 Calcium-dependent calmodulin binding DUF1768 PF08719.11 EKX45975.1 - 3.3e-30 105.4 0.0 3.7e-30 105.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF5054 PF16477.5 EKX45976.1 - 1e-05 25.5 0.5 0.0015 18.4 0.0 2.9 1 1 1 3 3 3 2 Domain of unknown function (DUF5054) CENP-H PF05837.12 EKX45977.1 - 0.035 14.5 19.4 0.2 12.1 11.9 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) ATG16 PF08614.11 EKX45977.1 - 0.68 10.1 23.1 0.038 14.2 14.1 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CLZ PF16526.5 EKX45977.1 - 0.78 10.1 17.2 2.8 8.4 0.4 3.6 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4407 PF14362.6 EKX45977.1 - 0.81 9.0 11.1 1.2 8.5 11.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 EKX45977.1 - 0.81 8.2 11.1 1.3 7.5 11.1 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A ADIP PF11559.8 EKX45977.1 - 0.99 9.5 24.8 3.1 7.9 14.6 3.0 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Cdh1_DBD_1 PF18196.1 EKX45977.1 - 1.1 9.6 11.9 0.59 10.5 6.7 2.3 2 1 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 APG6_N PF17675.1 EKX45977.1 - 1.2 9.6 25.5 0.57 10.7 8.6 2.4 1 1 0 2 2 2 0 Apg6 coiled-coil region DUF641 PF04859.12 EKX45977.1 - 1.5 9.1 17.2 0.19 12.1 11.1 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Fib_alpha PF08702.10 EKX45977.1 - 1.6 8.9 19.8 1.7 8.8 12.3 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Cnn_1N PF07989.11 EKX45977.1 - 2.3 8.4 18.7 5.8 7.1 1.9 3.5 1 1 1 3 3 3 0 Centrosomin N-terminal motif 1 DivIC PF04977.15 EKX45977.1 - 2.6 7.9 20.8 0.51 10.1 6.7 3.3 1 1 2 3 3 3 0 Septum formation initiator XhlA PF10779.9 EKX45977.1 - 4.3 7.6 13.0 0.91 9.8 2.2 3.5 3 0 0 3 3 3 0 Haemolysin XhlA Spc7 PF08317.11 EKX45977.1 - 6.6 5.5 23.2 0.84 8.5 15.6 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein FAM76 PF16046.5 EKX45977.1 - 8.3 5.7 16.7 13 5.0 16.7 1.3 1 0 0 1 1 1 0 FAM76 protein SLATT_6 PF18169.1 EKX45978.1 - 0.021 14.4 0.4 0.067 12.8 0.2 2.0 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 DUF948 PF06103.11 EKX45978.1 - 0.034 14.4 0.0 1.6 9.1 0.0 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CDC45 PF02724.14 EKX45978.1 - 0.074 11.3 2.6 0.11 10.7 2.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3106 PF11304.8 EKX45978.1 - 0.64 10.5 5.7 1.5 9.4 5.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) DUF3464 PF11947.8 EKX45978.1 - 1.6 8.5 4.4 3.4 7.4 4.4 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF1993 PF09351.10 EKX45979.1 - 0.00032 20.9 2.2 0.048 13.8 0.8 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1993) DUF3916 PF13079.6 EKX45979.1 - 0.041 13.8 0.3 0.05 13.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3916) CREPT PF16566.5 EKX45979.1 - 0.47 10.6 6.6 2.2 8.4 0.2 2.2 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour AMP-binding PF00501.28 EKX45980.1 - 1.6e-51 175.2 0.0 9.1e-27 93.7 0.0 2.2 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 EKX45980.1 - 9.7e-07 29.7 0.2 2.8e-06 28.2 0.1 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Histone PF00125.24 EKX45981.1 - 2.3e-17 63.6 0.0 2.7e-17 63.4 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EKX45981.1 - 0.00014 22.1 0.0 0.00017 21.8 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone FKBP_C PF00254.28 EKX45982.1 - 7.1e-36 122.4 0.1 8.2e-36 122.2 0.1 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Laminin_B PF00052.18 EKX45983.1 - 2.1e-16 60.0 0.0 4.1e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Laminin B (Domain IV) Ribosomal_S8 PF00410.19 EKX45984.1 - 5e-21 75.0 0.0 6.7e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Il2rg PF15874.5 EKX45985.1 - 7.4e-07 29.3 0.0 8.3e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Putative Interleukin 2 receptor, gamma chain Kelch_1 PF01344.25 EKX45986.1 - 1.1e-25 88.9 0.1 2.3e-10 39.9 0.0 3.6 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.6 EKX45986.1 - 7.1e-20 70.8 0.0 1.6e-07 31.2 0.0 3.4 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_6 PF13964.6 EKX45986.1 - 5.7e-17 61.3 0.0 2e-06 27.8 0.0 3.5 2 1 1 3 3 3 2 Kelch motif Kelch_2 PF07646.15 EKX45986.1 - 6.3e-10 38.6 1.0 9.5e-05 22.2 0.4 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 EKX45986.1 - 6.7e-08 32.6 0.6 0.00077 19.7 0.0 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 EKX45986.1 - 0.00014 21.8 0.1 0.015 15.2 0.1 2.9 3 0 0 3 3 3 1 Kelch motif TPR_MLP1_2 PF07926.12 EKX45986.1 - 0.0016 18.5 11.9 0.0016 18.5 11.9 8.8 5 2 3 8 8 8 1 TPR/MLP1/MLP2-like protein Mito_carr PF00153.27 EKX45987.1 - 3.6e-31 106.9 3.7 3.5e-13 49.3 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein zf-C3HC4_3 PF13920.6 EKX45988.1 - 3.3e-13 49.2 10.5 6.5e-13 48.3 10.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX45988.1 - 2.4e-06 27.3 13.2 5.1e-06 26.2 13.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EKX45988.1 - 4.3 7.2 9.4 11 5.9 9.4 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain NOA36 PF06524.12 EKX45989.1 - 1.1 8.5 14.8 2.7 7.3 14.8 1.6 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.25 EKX45990.1 - 1.4e-51 175.4 0.0 2.6e-51 174.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX45990.1 - 6.9e-26 91.1 0.0 1.4e-25 90.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX45990.1 - 2e-05 24.1 0.0 3.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like HEAT_2 PF13646.6 EKX45990.1 - 0.003 17.9 7.6 0.8 10.1 0.1 3.8 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.7 EKX45990.1 - 0.015 15.4 2.6 1.5 8.8 0.1 3.6 2 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EKX45990.1 - 0.024 15.1 3.6 5 7.7 0.2 4.8 4 1 0 4 4 4 0 HEAT-like repeat HEAT PF02985.22 EKX45990.1 - 0.076 13.3 9.3 15 6.2 0.0 6.3 7 0 0 7 7 7 0 HEAT repeat RICTOR_V PF14668.6 EKX45990.1 - 0.18 12.0 5.9 1.6 9.0 0.2 4.2 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.8 EKX45990.1 - 0.38 10.9 5.4 99 3.1 0.0 5.0 4 1 1 5 5 5 0 V-ATPase subunit H Arm PF00514.23 EKX45991.1 - 9.2e-21 73.2 61.7 0.0007 19.5 0.1 17.2 20 0 0 20 20 20 6 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EKX45991.1 - 1e-11 44.7 21.5 0.11 12.6 0.1 10.0 7 1 0 9 9 9 4 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 EKX45991.1 - 2.1e-07 31.2 62.6 0.00054 20.3 3.8 13.2 7 5 4 12 12 12 4 HEAT repeats Cnd1 PF12717.7 EKX45991.1 - 7e-06 26.2 21.8 0.032 14.3 0.0 8.2 7 3 3 10 10 10 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EKX45991.1 - 0.0041 17.6 0.5 0.0041 17.6 0.5 12.2 13 2 3 16 16 15 4 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EKX45991.1 - 0.012 16.2 11.4 0.54 10.9 0.1 7.2 8 0 0 8 8 8 0 Vacuolar 14 Fab1-binding region SDA1 PF05285.12 EKX45991.1 - 0.016 14.7 22.4 0.0051 16.3 15.2 2.5 2 0 0 2 2 2 0 SDA1 HEAT PF02985.22 EKX45991.1 - 0.016 15.4 0.1 0.016 15.4 0.1 12.4 16 0 0 16 16 13 0 HEAT repeat CCDC53 PF10152.9 EKX45991.1 - 1.9 8.9 15.1 8.5 6.8 7.7 2.9 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF3446 PF11928.8 EKX45991.1 - 2.1 8.7 14.4 3.9 7.8 4.0 3.1 2 0 0 2 2 2 0 Early growth response N-terminal domain KBP_C PF12309.8 EKX45991.1 - 4.2 6.8 16.9 1.5 8.3 8.9 3.4 3 0 0 3 3 3 0 KIF-1 binding protein C terminal PUL PF08324.11 EKX45991.1 - 5.5 6.1 28.2 0.092 12.0 0.5 7.0 4 2 3 8 8 8 0 PUL domain Eapp_C PF10238.9 EKX45991.1 - 5.5 7.0 17.1 1.5 8.9 2.5 3.1 3 0 0 3 3 3 0 E2F-associated phosphoprotein DUF5635 PF18685.1 EKX45992.1 - 0.12 12.3 0.1 0.6 10.1 0.0 2.2 3 0 0 3 3 3 0 Family of unknown function (DUF5635) BUD22 PF09073.10 EKX45993.1 - 4.1 6.6 15.0 5.7 6.2 15.0 1.2 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.14 EKX45993.1 - 4.6 7.0 7.5 7.8 6.2 7.5 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4147 PF13660.6 EKX45994.1 - 2.5e-59 200.6 3.0 5.4e-59 199.5 3.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4147) MOFRL PF05161.13 EKX45994.1 - 4.5e-15 55.8 0.1 1.4e-14 54.2 0.1 1.9 1 1 0 1 1 1 1 MOFRL family Abhydrolase_2 PF02230.16 EKX45995.1 - 4.3e-56 190.1 0.0 4.8e-56 190.0 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 EKX45995.1 - 7.8e-09 35.7 0.0 3.7e-05 23.7 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EKX45995.1 - 2.1e-08 33.8 0.0 0.00052 19.4 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EKX45995.1 - 6.3e-07 30.2 0.0 5.9e-06 27.0 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EKX45995.1 - 1.3e-06 28.1 0.1 8e-05 22.2 0.0 2.3 3 0 0 3 3 3 1 Prolyl oligopeptidase family FSH1 PF03959.13 EKX45995.1 - 2e-05 24.3 0.0 6.6e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 EKX45995.1 - 0.00012 21.7 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family PGAP1 PF07819.13 EKX45995.1 - 0.00024 20.9 0.0 0.00033 20.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 EKX45995.1 - 0.00089 19.4 0.0 0.001 19.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 EKX45995.1 - 0.0028 17.4 0.2 0.36 10.4 0.2 2.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 EKX45995.1 - 0.0061 16.4 0.0 0.01 15.7 0.0 1.5 1 1 0 1 1 1 1 Lipase (class 3) DUF1985 PF09331.11 EKX45995.1 - 0.01 15.8 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1985) Cutinase PF01083.22 EKX45995.1 - 0.013 15.5 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Cutinase Chlorophyllase2 PF12740.7 EKX45995.1 - 0.014 14.3 0.0 0.11 11.4 0.0 2.1 3 0 0 3 3 3 0 Chlorophyllase enzyme DUF2974 PF11187.8 EKX45995.1 - 0.026 14.1 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Chlorophyllase PF07224.11 EKX45995.1 - 0.14 11.2 0.0 0.41 9.6 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase Ank_3 PF13606.6 EKX45996.1 - 1.9e-07 30.8 0.7 0.0025 18.2 0.1 3.4 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EKX45996.1 - 2.9e-07 31.0 0.0 6.7e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX45996.1 - 9e-07 29.1 0.1 9.3e-05 22.7 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EKX45996.1 - 1.9e-06 28.3 1.2 0.0011 19.5 0.2 2.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX45996.1 - 9.2e-06 25.8 0.7 0.00067 19.9 0.1 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Fringe PF02434.16 EKX45996.1 - 0.01 15.3 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Fringe-like Pterin_bind PF00809.22 EKX45997.1 - 3.8e-83 278.9 0.0 5.8e-83 278.3 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 EKX45997.1 - 2.9e-36 124.4 0.0 5.7e-36 123.4 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) PEP_mutase PF13714.6 EKX45997.1 - 0.27 10.7 2.1 3.5 7.0 0.1 2.7 2 1 1 3 3 3 0 Phosphoenolpyruvate phosphomutase Potassium_chann PF11404.8 EKX45999.1 - 0.0086 15.9 4.3 11 5.9 0.1 3.2 3 0 0 3 3 3 3 Potassium voltage-gated channel DUF1388 PF07142.12 EKX45999.1 - 0.14 12.1 4.0 46 4.1 0.1 3.2 3 0 0 3 3 3 0 Repeat of unknown function (DUF1388) GH97_N PF14508.6 EKX46000.1 - 0.015 14.8 0.4 2.7 7.4 0.1 2.2 1 1 1 2 2 2 0 Glycosyl-hydrolase 97 N-terminal phage_tail_N PF08400.10 EKX46000.1 - 0.032 14.2 10.0 17 5.4 0.7 4.4 1 1 3 4 4 4 0 Prophage tail fibre N-terminal HGD-D PF06050.13 EKX46001.1 - 0.082 12.6 2.2 0.18 11.5 0.3 2.1 1 1 2 3 3 3 0 2-hydroxyglutaryl-CoA dehydratase, D-component SF-assemblin PF06705.11 EKX46001.1 - 0.14 11.5 20.0 0.21 10.9 20.0 1.3 1 0 0 1 1 1 0 SF-assemblin/beta giardin ImcF-related_N PF14331.6 EKX46001.1 - 0.24 10.7 4.9 0.24 10.7 0.3 2.2 2 0 0 2 2 2 0 ImcF-related N-terminal domain HU-CCDC81_bac_2 PF18175.1 EKX46001.1 - 1.2 9.0 3.8 3 7.8 0.3 2.9 3 0 0 3 3 3 0 CCDC81-like prokaryotic HU domain 2 DUF948 PF06103.11 EKX46001.1 - 2.3 8.5 4.3 5.2 7.4 1.1 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) KfrA_N PF11740.8 EKX46001.1 - 6 7.6 12.4 2.5 8.8 2.3 2.6 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term zf-CCCH PF00642.24 EKX46003.1 - 4.5e-15 55.1 25.7 5.6e-06 26.1 1.6 3.3 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EKX46003.1 - 4.8e-09 36.9 2.8 0.063 14.0 0.0 3.3 3 0 0 3 3 3 3 Torus domain zf_CCCH_4 PF18345.1 EKX46003.1 - 3.2e-06 27.0 33.9 8.4e-05 22.5 5.4 3.4 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 EKX46003.1 - 0.005 16.6 4.4 0.005 16.6 4.4 3.7 3 1 0 3 3 3 1 CCCH-type zinc finger Metallophos PF00149.28 EKX46004.1 - 5.5e-15 56.4 0.0 8.4e-15 55.8 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EKX46004.1 - 2.4e-07 31.1 0.0 3.5e-07 30.6 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 EKX46004.1 - 0.018 14.4 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Sod_Fe_C PF02777.18 EKX46005.1 - 1.1e-36 125.1 0.6 1.7e-36 124.5 0.6 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EKX46005.1 - 4.3e-20 72.0 0.9 7.7e-20 71.2 0.1 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Collagen PF01391.18 EKX46006.1 - 1.9e-10 40.3 24.3 2.5e-09 36.7 24.3 1.9 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) tRNA-synt_1b PF00579.25 EKX46007.1 - 5e-62 209.9 0.0 1.1e-49 169.4 0.0 3.8 2 2 0 2 2 2 2 tRNA synthetases class I (W and Y) WHEP-TRS PF00458.20 EKX46007.1 - 8.8e-07 29.0 5.0 3.4e-06 27.1 5.0 2.0 1 0 0 1 1 1 1 WHEP-TRS domain SSF PF00474.17 EKX46008.1 - 9.3e-25 87.3 19.1 1.7e-24 86.4 19.1 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family DUF997 PF06196.12 EKX46008.1 - 9.8 6.3 10.1 0.91 9.6 3.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF997) CENP-T_C PF15511.6 EKX46009.1 - 4.1e-09 36.5 0.1 5e-09 36.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EKX46009.1 - 0.0001 22.6 0.1 0.00014 22.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 EKX46009.1 - 0.0001 22.4 0.2 0.00014 21.9 0.2 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 EKX46009.1 - 0.00021 21.7 0.3 0.00024 21.5 0.3 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EKX46009.1 - 0.00042 20.5 0.1 0.00064 19.9 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EKX46009.1 - 0.0073 16.4 0.0 0.0085 16.2 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EKX46009.1 - 0.013 15.5 0.1 0.02 14.9 0.1 1.2 1 0 0 1 1 1 0 Bromodomain associated PseudoU_synth_2 PF00849.22 EKX46010.1 - 8.3e-25 87.7 0.4 3.4e-24 85.7 0.1 2.2 2 1 0 2 2 2 1 RNA pseudouridylate synthase S4 PF01479.25 EKX46010.1 - 2.5e-06 27.1 0.1 6e-06 25.9 0.1 1.7 1 0 0 1 1 1 1 S4 domain POC3_POC4 PF10448.9 EKX46011.1 - 0.062 13.3 0.0 13 5.7 0.0 2.2 2 0 0 2 2 2 0 20S proteasome chaperone assembly proteins 3 and 4 FHA PF00498.26 EKX46012.1 - 3.1e-13 49.9 0.1 5.6e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EKX46012.1 - 5.6e-11 42.6 0.1 9.3e-10 38.7 0.1 2.2 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain WD40 PF00400.32 EKX46014.1 - 8.1e-34 115.1 9.9 1.1e-05 26.0 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX46014.1 - 3e-15 56.3 0.0 0.0049 17.1 0.0 4.5 1 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EKX46014.1 - 2e-06 27.8 0.0 0.028 14.3 0.0 2.7 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EKX46014.1 - 5.5e-06 25.6 0.2 0.63 8.9 0.0 3.6 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EKX46014.1 - 0.0001 21.7 0.0 2 7.7 0.1 3.1 2 1 1 3 3 3 2 WD40-like domain Frtz PF11768.8 EKX46014.1 - 0.013 13.8 0.0 1.9 6.7 0.0 2.7 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 EKX46014.1 - 0.018 14.4 0.0 0.49 9.7 0.0 2.4 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal PQQ_3 PF13570.6 EKX46014.1 - 0.03 14.8 0.0 4.6 7.9 0.0 3.5 4 0 0 4 4 4 0 PQQ-like domain Cytochrom_D1 PF02239.16 EKX46014.1 - 0.058 11.9 0.0 0.4 9.2 0.0 2.0 1 1 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.12 EKX46014.1 - 0.089 12.8 0.2 11 6.1 0.1 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Hint PF01079.20 EKX46015.1 - 3.5e-06 26.7 0.0 5.7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Hint module Zip PF02535.22 EKX46016.1 - 8e-47 160.1 4.7 1.2e-46 159.5 4.7 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Hydrolase_like PF13242.6 EKX46016.1 - 9.2e-06 25.6 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like FAT PF02259.23 EKX46017.1 - 1.6e-78 264.4 4.0 1.6e-78 264.4 4.0 3.6 4 1 0 4 4 4 1 FAT domain PI3_PI4_kinase PF00454.27 EKX46017.1 - 4.3e-70 236.4 0.3 2.2e-69 234.1 0.1 2.3 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 EKX46017.1 - 4.6e-50 169.7 8.1 5.5e-48 162.9 0.5 4.6 4 1 0 4 4 4 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 EKX46017.1 - 3.3e-37 126.9 2.3 3.3e-37 126.9 2.3 3.0 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 EKX46017.1 - 4.6e-11 42.9 10.5 0.00064 20.1 0.0 8.3 9 1 0 10 10 9 2 HEAT repeats Adaptin_N PF01602.20 EKX46017.1 - 4.3e-09 35.5 5.6 0.00076 18.2 0.6 3.4 3 1 0 3 3 3 2 Adaptin N terminal region HEAT PF02985.22 EKX46017.1 - 2.6e-08 33.4 21.3 5.2 7.6 0.0 10.9 11 0 0 11 11 10 2 HEAT repeat HEAT_EZ PF13513.6 EKX46017.1 - 2.4e-07 31.1 7.5 0.79 10.3 0.0 8.4 7 0 0 7 7 7 1 HEAT-like repeat Cnd1 PF12717.7 EKX46017.1 - 5e-06 26.7 2.6 0.54 10.3 0.1 4.8 2 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 EKX46017.1 - 1.4e-05 24.9 2.2 0.53 10.2 0.3 5.1 5 0 0 5 5 5 2 UME (NUC010) domain Vac14_Fab1_bd PF12755.7 EKX46017.1 - 2.7e-05 24.7 4.8 2.7 8.6 0.0 6.4 5 2 1 6 6 6 1 Vacuolar 14 Fab1-binding region Dopey_N PF04118.14 EKX46017.1 - 6.3e-05 22.2 3.3 0.0027 16.9 1.1 3.3 2 1 0 2 2 2 1 Dopey, N-terminal TPR_20 PF14561.6 EKX46017.1 - 0.0051 17.1 0.0 0.25 11.7 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat Sec7_N PF12783.7 EKX46017.1 - 0.026 14.4 6.0 6.5 6.6 0.0 5.0 6 0 0 6 6 6 0 Guanine nucleotide exchange factor in Golgi transport N-terminal RTP1_C1 PF10363.9 EKX46017.1 - 0.14 12.4 0.1 94 3.2 0.0 4.8 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 TPR_12 PF13424.6 EKX46017.1 - 0.3 11.4 1.8 3 8.2 1.8 2.9 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4042 PF13251.6 EKX46017.1 - 0.82 9.3 5.1 2.4 7.8 0.1 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) Beta-Casp PF10996.8 EKX46018.1 - 2.1e-24 85.9 0.0 3.7e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 EKX46018.1 - 1.4e-18 67.0 0.0 2.8e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 EKX46018.1 - 1.2e-14 54.0 0.1 2.9e-14 52.7 0.1 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 EKX46018.1 - 3.6e-14 53.2 0.0 3e-13 50.2 0.0 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EKX46018.1 - 7e-09 35.5 0.0 1.5e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EKX46018.1 - 5.3e-05 23.2 0.0 0.00036 20.5 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 EKX46018.1 - 0.012 14.9 0.0 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 Putative beta-lactamase-like family E1-E2_ATPase PF00122.20 EKX46019.1 - 9.3e-39 132.8 0.3 1.8e-38 131.9 0.3 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EKX46019.1 - 7.2e-31 108.1 0.0 1.1e-30 107.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EKX46019.1 - 1.9e-09 37.6 0.1 2.1e-05 24.4 0.1 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EKX46019.1 - 0.00027 21.4 0.0 0.00063 20.2 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ELMO_CED12 PF04727.13 EKX46021.1 - 5e-31 108.2 0.0 5.9e-31 107.9 0.0 1.0 1 0 0 1 1 1 1 ELMO/CED-12 family Actin PF00022.19 EKX46022.1 - 3.4e-100 335.5 0.0 2.5e-99 332.6 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EKX46022.1 - 0.0025 16.7 0.0 0.0046 15.8 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein RexA PF15969.5 EKX46022.1 - 0.05 13.2 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 Intracellular sensor of Lambda phage, Abi component NIF PF03031.18 EKX46023.1 - 4.5e-50 169.4 0.0 6.8e-50 168.9 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase MINDY_DUB PF04424.13 EKX46024.1 - 3e-32 111.1 0.3 7.3e-32 109.8 0.3 1.7 1 0 0 1 1 1 1 MINDY deubiquitinase TMA7 PF09072.10 EKX46024.1 - 2.1 9.3 6.5 16 6.4 3.7 2.7 2 0 0 2 2 2 0 Translation machinery associated TMA7 Roughex PF06020.11 EKX46024.1 - 6.5 5.8 10.6 14 4.6 10.6 1.6 1 0 0 1 1 1 0 Drosophila roughex protein RRM_1 PF00076.22 EKX46025.1 - 2.5e-19 68.8 0.0 3e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EKX46025.1 - 0.16 11.5 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PKD_channel PF08016.12 EKX46026.1 - 9.3e-45 153.1 14.9 9.3e-45 153.1 14.9 1.4 2 0 0 2 2 2 1 Polycystin cation channel EMC1_C PF07774.13 EKX46027.1 - 1.1e-67 227.9 0.4 2e-67 227.0 0.4 1.5 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 EKX46027.1 - 3.2e-10 40.0 7.9 1.8e-06 27.7 4.3 4.0 3 1 1 4 4 4 2 PQQ-like domain DUF1926 PF09095.11 EKX46027.1 - 0.016 14.8 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1926) VCBS PF13517.6 EKX46027.1 - 0.017 15.7 0.3 0.14 12.8 0.7 2.3 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella SNF2_N PF00176.23 EKX46028.1 - 7.1e-28 97.3 0.1 1.6e-27 96.2 0.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX46028.1 - 5.2e-17 62.2 0.0 1.1e-16 61.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EKX46028.1 - 7.8e-05 22.0 0.4 0.00019 20.7 0.4 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DnaI_N PF07319.11 EKX46028.1 - 0.064 13.9 1.9 0.15 12.7 1.9 1.6 1 0 0 1 1 1 0 Primosomal protein DnaI N-terminus SNF2_N PF00176.23 EKX46029.1 - 1.3e-21 76.8 0.1 1.3e-20 73.4 0.0 1.7 1 1 1 2 2 2 2 SNF2 family N-terminal domain ResIII PF04851.15 EKX46029.1 - 4.5e-07 30.0 0.0 5.2e-07 29.8 0.0 1.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DICT PF10069.9 EKX46029.1 - 0.018 14.8 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Sensory domain in DIguanylate Cyclases and Two-component system REV1_C PF16727.5 EKX46029.1 - 0.16 12.4 0.0 0.34 11.3 0.0 1.5 1 1 0 1 1 1 0 DNA repair protein REV1 C-terminal domain NAD_kinase PF01513.21 EKX46030.1 - 5.1e-57 193.3 0.0 6.6e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EKX46030.1 - 0.0017 18.0 0.9 0.0027 17.3 0.1 1.7 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain Pirin PF02678.16 EKX46031.1 - 8.6e-28 96.5 0.0 1.8e-27 95.4 0.0 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EKX46031.1 - 3.3e-26 91.7 0.0 9e-26 90.3 0.0 1.7 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 EKX46031.1 - 0.00019 21.1 2.0 0.038 13.7 0.2 2.9 3 0 0 3 3 3 2 Cupin domain PNP_UDP_1 PF01048.20 EKX46033.1 - 1.3e-47 162.0 0.2 1.6e-47 161.8 0.2 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily PDZ_6 PF17820.1 EKX46035.1 - 1.7e-10 40.6 0.1 2.6e-10 40.0 0.1 1.2 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX46035.1 - 3.1e-07 30.6 0.3 4e-07 30.3 0.3 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX46035.1 - 1.7e-05 25.0 0.0 2.6e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX46035.1 - 0.018 15.0 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Tricorn protease PDZ domain TPR_12 PF13424.6 EKX46037.1 - 2.9e-08 33.9 2.8 2.9e-07 30.7 0.2 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX46037.1 - 1e-07 31.4 2.5 0.026 14.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX46037.1 - 1.5e-06 27.8 3.7 0.091 12.9 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX46037.1 - 9.3e-06 25.3 0.3 0.55 10.4 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX46037.1 - 7.4e-05 23.1 4.5 0.039 14.6 0.5 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX46037.1 - 0.0015 18.6 11.2 0.36 11.1 0.2 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX46037.1 - 0.0057 17.4 0.0 5.7 8.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat HSP20 PF00011.21 EKX46037.1 - 0.1 12.8 0.2 0.28 11.3 0.0 1.7 2 0 0 2 2 2 0 Hsp20/alpha crystallin family TPR_10 PF13374.6 EKX46037.1 - 0.11 12.4 0.2 20 5.3 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX46037.1 - 0.16 12.5 0.4 1.5 9.4 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat Vta1 PF04652.16 EKX46037.1 - 0.18 11.8 1.9 1.5 8.8 0.4 2.4 2 0 0 2 2 2 0 Vta1 like Ndufs5 PF10200.9 EKX46039.1 - 0.0002 21.6 1.5 0.00059 20.0 1.5 1.8 1 1 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa PADR1 PF08063.12 EKX46039.1 - 0.1 12.4 0.3 0.1 12.4 0.3 2.0 3 0 0 3 3 3 0 PADR1 (NUC008) domain COX6B PF02297.17 EKX46039.1 - 0.72 10.1 9.0 1.6 9.0 0.4 2.4 2 1 1 3 3 3 0 Cytochrome oxidase c subunit VIb SdiA-regulated PF06977.11 EKX46040.1 - 1e-09 38.0 0.0 2.1e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 SdiA-regulated Rnk_N PF14760.6 EKX46042.1 - 7.1e-05 23.2 3.6 5.2 7.6 0.0 5.4 6 0 0 6 6 6 3 Rnk N-terminus Glyco_transf_4 PF13439.6 EKX46043.1 - 5.3e-19 68.9 0.4 8.8e-18 64.9 0.4 2.2 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EKX46043.1 - 4.3e-08 32.9 0.1 2e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EKX46043.1 - 7.9e-08 32.8 0.1 3.8e-07 30.6 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EKX46043.1 - 9.4e-08 32.7 0.0 1.8e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 EKX46043.1 - 4e-05 23.7 0.0 7.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like MAM33 PF02330.16 EKX46044.1 - 1.7e-10 41.2 0.3 8e-10 39.0 0.3 2.0 1 1 0 1 1 1 1 Mitochondrial glycoprotein Snurportin1 PF11538.8 EKX46045.1 - 0.009 16.2 7.6 0.019 15.2 7.6 1.5 1 0 0 1 1 1 1 Snurportin1 SAT PF16073.5 EKX46045.1 - 0.051 13.3 0.0 0.08 12.7 0.0 1.2 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Histone_HNS PF00816.21 EKX46045.1 - 0.13 13.1 2.1 0.29 12.0 2.1 1.6 1 0 0 1 1 1 0 H-NS histone family Steroid_dh PF02544.16 EKX46046.1 - 2.4e-11 43.8 2.9 2.4e-11 43.8 2.9 1.8 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF2544 PF11245.8 EKX46046.1 - 0.02 14.4 0.1 0.034 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2544) CTP_transf_1 PF01148.20 EKX46046.1 - 5.5 6.7 11.6 0.13 12.0 2.1 2.2 2 1 0 2 2 2 0 Cytidylyltransferase family Sulfotransfer_1 PF00685.27 EKX46047.1 - 3.2e-42 144.9 0.1 5.6e-42 144.1 0.0 1.4 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EKX46047.1 - 1.7e-10 41.6 0.1 1.1e-05 25.9 0.2 2.6 2 0 0 2 2 2 2 Sulfotransferase family zf_CCCH_4 PF18345.1 EKX46047.1 - 0.24 11.5 5.4 0.15 12.2 1.6 2.4 1 1 1 2 2 2 0 Zinc finger domain adh_short PF00106.25 EKX46048.1 - 1.2e-20 73.8 0.0 1.7e-13 50.5 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EKX46048.1 - 2.8e-16 59.8 0.2 9.7e-08 31.8 0.1 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase DUF1433 PF07252.11 EKX46048.1 - 0.13 12.5 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1433) SYF2 PF08231.12 EKX46049.1 - 4.4e-38 131.2 11.0 4.4e-38 131.2 11.0 2.0 1 1 1 2 2 2 1 SYF2 splicing factor Alg6_Alg8 PF03155.15 EKX46050.1 - 1.2e-118 397.2 16.8 1.1e-117 394.0 16.8 1.9 1 1 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family ATPase_gene1 PF09527.10 EKX46050.1 - 0.79 9.9 5.0 0.61 10.3 0.5 2.6 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter HAD_2 PF13419.6 EKX46051.1 - 1.3e-12 48.2 0.0 1.7e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EKX46051.1 - 7.2e-05 22.8 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EKX46051.1 - 8.6e-05 22.9 0.0 0.00014 22.2 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EKX46051.1 - 0.15 12.4 0.0 0.23 11.9 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase MAM33 PF02330.16 EKX46052.1 - 1.3e-10 41.6 0.1 4e-09 36.7 0.1 2.2 1 1 0 1 1 1 1 Mitochondrial glycoprotein BTB PF00651.31 EKX46053.1 - 1.8e-18 66.8 0.0 5.5e-17 62.0 0.0 2.4 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 EKX46053.1 - 2.2e-10 40.6 0.8 6.7e-10 39.0 0.2 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch DUF3342 PF11822.8 EKX46053.1 - 6.7e-06 26.2 0.0 3.4e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) Tricorn_PDZ PF14685.6 EKX46053.1 - 0.003 17.5 0.0 0.0056 16.6 0.0 1.4 1 0 0 1 1 1 1 Tricorn protease PDZ domain PDZ_2 PF13180.6 EKX46053.1 - 0.023 15.0 0.0 0.051 13.9 0.0 1.6 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 EKX46053.1 - 0.16 11.8 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 PDZ domain GTP_EFTU PF00009.27 EKX46054.1 - 1.2e-59 201.1 0.1 1.7e-59 200.6 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EKX46054.1 - 9.7e-29 99.6 0.4 1.2e-27 96.1 0.0 2.8 4 0 0 4 4 4 1 Elongation factor G, domain IV EFG_C PF00679.24 EKX46054.1 - 1.6e-21 76.1 0.0 4.1e-21 74.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 EKX46054.1 - 1.1e-14 54.3 0.2 7.8e-14 51.5 0.0 2.4 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EKX46054.1 - 1.9e-13 50.6 0.2 7.3e-13 48.7 0.2 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EKX46054.1 - 0.007 16.4 0.1 0.014 15.5 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 EKX46054.1 - 0.079 12.8 0.0 0.24 11.2 0.0 1.7 2 0 0 2 2 2 0 Class II release factor RF3, C-terminal domain tRNA_NucTran2_2 PF13735.6 EKX46054.1 - 0.12 12.3 0.3 0.65 10.0 0.1 2.2 3 0 0 3 3 3 0 tRNA nucleotidyltransferase domain 2 putative SNF2_N PF00176.23 EKX46055.1 - 9.6e-64 215.3 0.0 1.3e-63 214.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX46055.1 - 3.9e-14 52.9 0.0 9.1e-13 48.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 EKX46055.1 - 2e-05 24.3 4.3 5.4e-05 22.9 4.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX46055.1 - 2.3e-05 24.3 2.7 2.3e-05 24.3 2.7 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EKX46055.1 - 2.4e-05 24.2 4.9 0.00011 22.0 4.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 EKX46055.1 - 0.00017 21.8 5.7 0.00017 21.8 5.7 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 EKX46055.1 - 0.00029 20.6 6.3 0.00072 19.4 6.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX46055.1 - 0.00038 20.3 5.6 0.0011 18.8 5.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ERCC3_RAD25_C PF16203.5 EKX46055.1 - 0.0034 16.6 0.1 0.0093 15.2 0.0 1.7 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Prok-RING_4 PF14447.6 EKX46055.1 - 0.052 13.4 9.0 0.033 14.0 6.4 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EKX46055.1 - 0.12 12.5 4.5 0.33 11.1 4.5 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EKX46055.1 - 0.17 11.7 9.0 0.79 9.5 9.0 2.3 1 0 0 1 1 1 0 RING-like zinc finger Methyltransf_21 PF05050.12 EKX46056.1 - 3e-12 46.9 0.0 5.7e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Met_10 PF02475.16 EKX46056.1 - 0.00054 19.8 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein V_cholerae_RfbT PF05575.11 EKX46056.1 - 0.017 14.4 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 Vibrio cholerae RfbT protein PRMT5 PF05185.16 EKX46056.1 - 0.04 13.8 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase SAM_MT PF04445.13 EKX46056.1 - 0.17 11.3 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase TPR_17 PF13431.6 EKX46058.1 - 1e-15 56.8 24.5 6.6e-05 23.0 0.1 9.7 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 EKX46058.1 - 8.9e-14 51.8 17.9 2.7e-05 24.6 0.6 7.2 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX46058.1 - 4.7e-13 48.8 12.0 0.031 15.1 0.1 8.9 6 2 4 10 10 9 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX46058.1 - 4.9e-13 48.1 20.9 0.00016 21.5 0.1 9.8 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX46058.1 - 3.7e-12 45.5 19.2 6.5e-05 22.6 0.0 9.5 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX46058.1 - 7.3e-11 41.6 16.7 0.0017 18.0 0.1 7.3 8 0 0 8 8 8 3 TPR repeat TPR_8 PF13181.6 EKX46058.1 - 2.4e-09 36.7 8.5 0.016 15.4 0.0 8.4 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX46058.1 - 1.2e-07 32.2 12.6 0.063 13.9 0.5 5.8 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX46058.1 - 4.1e-07 29.6 0.9 0.022 14.7 0.1 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX46058.1 - 0.00079 19.6 8.8 0.0041 17.3 1.8 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EKX46058.1 - 0.0031 17.6 3.4 2 8.6 0.0 5.0 5 1 0 5 5 5 1 Tetratricopeptide repeat DUF4919 PF16266.5 EKX46058.1 - 0.052 13.5 2.2 6 6.8 0.0 3.7 2 2 2 4 4 4 0 Domain of unknown function (DUF4919) TPR_12 PF13424.6 EKX46058.1 - 0.068 13.5 16.6 0.96 9.8 0.1 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Spore-coat_CotD PF11122.8 EKX46058.1 - 0.14 13.0 0.0 0.31 11.9 0.0 1.5 1 0 0 1 1 1 0 Inner spore coat protein D TPR_20 PF14561.6 EKX46058.1 - 0.24 11.7 3.3 11 6.4 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX46058.1 - 0.81 10.5 11.6 16 6.4 0.0 5.8 7 1 0 7 7 4 0 Tetratricopeptide repeat RPAP1_N PF08621.10 EKX46059.1 - 0.00041 20.0 2.1 0.00041 20.0 2.1 2.5 2 0 0 2 2 2 1 RPAP1-like, N-terminal Flt3_lig PF02947.14 EKX46059.1 - 0.11 12.7 1.1 0.99 9.6 1.1 2.2 1 1 0 1 1 1 0 flt3 ligand ATP-synt_B PF00430.18 EKX46059.1 - 9.1 6.4 13.2 20 5.2 13.2 1.6 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) CheD PF03975.13 EKX46060.1 - 0.13 12.4 3.7 81 3.4 0.0 4.6 1 1 6 7 7 7 0 CheD chemotactic sensory transduction RIH_assoc PF08454.11 EKX46061.1 - 3.8e-21 74.8 1.8 3.8e-21 74.8 1.8 2.8 2 0 0 2 2 2 1 RyR and IP3R Homology associated Ins145_P3_rec PF08709.11 EKX46061.1 - 4.7e-18 65.2 1.1 9e-17 61.0 0.0 3.4 3 1 1 4 4 4 1 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 EKX46061.1 - 7e-11 42.3 1.9 1.4e-05 25.0 0.1 3.4 2 1 1 3 3 3 2 MIR domain RYDR_ITPR PF01365.21 EKX46061.1 - 2e-10 40.4 22.4 2.2e-08 33.8 1.5 4.3 5 0 0 5 5 5 2 RIH domain cNMP_binding PF00027.29 EKX46061.1 - 9.3e-10 38.5 0.1 2.9e-09 36.9 0.1 1.9 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 EKX46061.1 - 1.9e-08 33.9 6.1 1.9e-08 33.9 6.1 2.6 3 0 0 3 3 3 1 Ion transport protein NOA36 PF06524.12 EKX46061.1 - 0.83 8.9 11.4 1.6 8.0 11.4 1.4 1 0 0 1 1 1 0 NOA36 protein hnRNP_Q_AcD PF18360.1 EKX46063.1 - 1.9e-61 203.9 1.0 1.3e-26 92.3 0.0 3.2 3 0 0 3 3 3 3 Heterogeneous nuclear ribonucleoprotein Q acidic domain DUF2023 PF09633.10 EKX46063.1 - 0.033 14.3 0.1 23 5.2 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2023) SpoIIIAH PF12685.7 EKX46063.1 - 3.9 7.2 12.0 7.5 6.3 11.6 1.6 2 0 0 2 2 2 0 SpoIIIAH-like protein Abhydrolase_1 PF00561.20 EKX46065.1 - 3.3e-20 72.8 0.0 1.4e-17 64.2 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EKX46065.1 - 1.3e-18 68.4 0.3 1.7e-18 68.0 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EKX46065.1 - 4.3e-14 52.4 0.0 3.8e-12 46.0 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EKX46065.1 - 1.3e-07 31.9 0.2 2.3e-07 31.1 0.2 1.4 1 0 0 1 1 1 1 Thioesterase domain Ndr PF03096.14 EKX46065.1 - 1.7e-06 27.0 0.0 1.9e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Ndr family Chlorophyllase2 PF12740.7 EKX46065.1 - 0.0002 20.4 0.0 0.0003 19.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 EKX46065.1 - 0.00054 19.8 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EKX46065.1 - 0.00094 19.1 0.0 0.0023 17.8 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 EKX46065.1 - 0.022 14.6 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2920 PF11144.8 EKX46065.1 - 0.075 12.2 0.1 8.1 5.5 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) PAF-AH_p_II PF03403.13 EKX46065.1 - 0.12 10.9 0.0 0.72 8.3 0.0 1.9 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Esterase PF00756.20 EKX46065.1 - 0.22 11.1 0.0 0.42 10.2 0.0 1.4 1 0 0 1 1 1 0 Putative esterase C2 PF00168.30 EKX46066.1 - 2.4e-25 88.8 0.0 2.8e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 C2 domain Ion_trans PF00520.31 EKX46067.1 - 5.1e-197 651.4 90.5 1.7e-54 184.7 15.0 4.1 4 0 0 4 4 4 4 Ion transport protein GPHH PF16905.5 EKX46067.1 - 5.7e-08 32.4 0.0 1.3e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated PKD_channel PF08016.12 EKX46067.1 - 0.0092 14.7 0.4 0.0092 14.7 0.4 8.0 6 3 2 8 8 8 5 Polycystin cation channel NMO PF03060.15 EKX46068.1 - 9.1e-11 41.7 0.2 0.00012 21.6 0.0 2.4 2 1 0 2 2 2 2 Nitronate monooxygenase EF-hand_1 PF00036.32 EKX46069.1 - 5e-18 63.2 7.0 0.0017 17.7 0.3 4.5 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 EKX46069.1 - 3.9e-14 51.4 9.4 0.0013 18.1 0.2 5.2 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 EKX46069.1 - 8.9e-14 51.7 13.2 3e-07 30.8 1.6 3.7 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 EKX46069.1 - 7.5e-13 47.3 5.9 0.0066 16.3 0.0 4.7 5 0 0 5 5 5 4 EF-hand domain SPARC_Ca_bdg PF10591.9 EKX46069.1 - 6.1e-09 36.2 1.4 0.00085 19.6 0.0 3.3 3 0 0 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 EKX46069.1 - 7.2e-05 22.6 5.1 1.5 8.7 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain pair Dockerin_1 PF00404.18 EKX46069.1 - 0.23 11.7 0.7 3.1 8.1 0.1 2.9 3 1 0 3 3 3 0 Dockerin type I domain Zn_clus PF00172.18 EKX46071.1 - 1.9e-05 24.7 17.6 8e-05 22.7 4.8 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain NPV_P10 PF05531.12 EKX46072.1 - 0.0011 19.4 0.7 0.0011 19.4 0.7 8.3 8 2 0 8 8 8 2 Nucleopolyhedrovirus P10 protein DASH_Duo1 PF08651.10 EKX46072.1 - 0.059 13.2 0.2 0.059 13.2 0.2 6.9 7 0 0 7 7 7 0 DASH complex subunit Duo1 Baculo_PEP_C PF04513.12 EKX46072.1 - 1.2 9.2 40.1 5.3 7.1 2.6 9.2 6 3 3 10 10 10 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pkinase PF00069.25 EKX46074.1 - 2.1e-53 181.4 0.0 2.4e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX46074.1 - 1.9e-36 125.7 0.0 2.3e-36 125.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX46074.1 - 0.019 14.3 0.0 0.27 10.5 0.0 2.1 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 EKX46074.1 - 0.054 13.4 0.0 2.6 7.9 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family LURAP PF14854.6 EKX46075.1 - 0.028 14.4 1.1 1.4 8.9 0.6 2.6 2 0 0 2 2 2 0 Leucine rich adaptor protein RNR_Alpha PF17975.1 EKX46075.1 - 0.029 14.9 1.7 0.055 14.0 0.1 2.2 2 0 0 2 2 2 0 Ribonucleotide reductase alpha domain Antimicrobial_7 PF08102.11 EKX46075.1 - 0.16 12.2 0.8 0.45 10.8 0.8 1.8 1 0 0 1 1 1 0 Scorpion antimicrobial peptide DUF1464 PF07318.12 EKX46075.1 - 0.22 10.6 3.5 0.1 11.7 1.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1464) ACP_PD PF04336.12 EKX46075.1 - 0.46 10.9 3.1 0.68 10.4 0.2 2.6 2 1 0 2 2 2 0 Acyl carrier protein phosphodiesterase Band_7 PF01145.25 EKX46075.1 - 0.47 10.4 3.3 1 9.3 3.3 1.5 1 0 0 1 1 1 0 SPFH domain / Band 7 family Cep57_MT_bd PF06657.13 EKX46075.1 - 1.4 9.5 8.5 0.4 11.2 2.7 3.1 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 XhlA PF10779.9 EKX46075.1 - 1.4 9.2 9.0 0.59 10.4 1.8 3.5 3 0 0 3 3 3 0 Haemolysin XhlA UPF0242 PF06785.11 EKX46075.1 - 3.2 7.8 20.4 4.9 7.2 5.2 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus B9-C2 PF07162.11 EKX46076.1 - 3.3e-41 141.3 0.0 5.4e-41 140.6 0.0 1.3 1 1 0 1 1 1 1 Ciliary basal body-associated, B9 protein PAP_fibrillin PF04755.12 EKX46077.1 - 2.1e-19 70.3 0.2 1.9e-11 44.3 0.1 3.0 2 1 0 2 2 2 2 PAP_fibrillin HTH_Tnp_Tc5 PF03221.16 EKX46077.1 - 0.023 14.7 0.1 0.046 13.7 0.1 1.5 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain LRR_6 PF13516.6 EKX46078.1 - 1.4e-12 46.6 19.8 0.00032 20.5 0.1 10.9 12 0 0 12 12 12 3 Leucine Rich repeat LRR_8 PF13855.6 EKX46078.1 - 2.4e-08 33.6 26.5 0.00097 18.8 0.3 8.3 8 1 0 8 8 8 4 Leucine rich repeat LRR_4 PF12799.7 EKX46078.1 - 0.00014 22.1 27.5 0.22 12.0 0.1 9.8 8 2 2 10 10 10 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX46078.1 - 0.25 12.0 24.4 21 6.1 0.0 9.6 9 1 0 9 9 9 0 Leucine Rich Repeat Pox_Ag35 PF03286.14 EKX46078.1 - 0.28 10.9 2.6 0.58 9.9 0.3 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF2417 PF10329.9 EKX46079.1 - 0.028 13.8 1.5 0.035 13.5 1.5 1.1 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Peptidase_M50 PF02163.22 EKX46081.1 - 6e-05 22.4 0.4 0.00015 21.1 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M50 IGPS PF00218.21 EKX46083.1 - 5.2e-35 120.8 0.0 5.5e-34 117.5 0.0 2.0 1 1 0 1 1 1 1 Indole-3-glycerol phosphate synthase NanE PF04131.14 EKX46083.1 - 0.0042 16.3 0.2 1.7 7.8 0.1 2.6 2 1 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase DUF2564 PF10819.8 EKX46083.1 - 0.028 14.8 0.3 0.25 11.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2564) FAM76 PF16046.5 EKX46085.1 - 0.046 13.1 6.0 0.061 12.7 6.0 1.1 1 0 0 1 1 1 0 FAM76 protein Peptidase_S41 PF03572.18 EKX46086.1 - 1.1e-28 99.9 0.1 1.7e-28 99.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 EKX46086.1 - 4.2e-05 23.3 0.1 0.00014 21.7 0.1 2.0 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX46086.1 - 0.00079 19.7 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain ABC_tran PF00005.27 EKX46087.1 - 6.2e-16 59.1 0.0 7e-11 42.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter Sec20 PF03908.13 EKX46088.1 - 9e-07 28.7 3.8 6.5e-06 26.0 0.4 3.1 2 1 1 3 3 3 1 Sec20 V-SNARE_C PF12352.8 EKX46088.1 - 0.0004 20.6 2.7 0.0004 20.6 2.7 2.8 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Prominin PF05478.11 EKX46088.1 - 0.0031 15.6 11.9 0.013 13.5 11.9 1.8 1 1 0 1 1 1 1 Prominin Alpha_E2_glycop PF00943.19 EKX46088.1 - 0.0036 16.1 0.2 0.0051 15.6 0.2 1.2 1 0 0 1 1 1 1 Alphavirus E2 glycoprotein Baculo_PEP_C PF04513.12 EKX46088.1 - 0.16 12.0 0.1 0.16 12.0 0.1 3.3 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Herpes_pp85 PF04637.12 EKX46088.1 - 0.32 9.4 7.3 0.21 9.9 5.3 1.7 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) HisKA PF00512.25 EKX46088.1 - 0.41 10.7 3.2 1.7 8.7 0.1 2.8 3 0 0 3 3 2 0 His Kinase A (phospho-acceptor) domain DUF948 PF06103.11 EKX46088.1 - 0.46 10.8 14.2 1.4 9.2 0.4 3.9 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Rx_N PF18052.1 EKX46088.1 - 0.83 10.0 7.7 0.84 9.9 1.1 2.8 3 0 0 3 3 2 0 Rx N-terminal domain V-SNARE PF05008.15 EKX46088.1 - 1.7 9.1 14.1 0.094 13.1 2.7 3.6 3 1 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF1664 PF07889.12 EKX46088.1 - 2.8 8.0 15.3 2.8 8.0 1.5 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) SOGA PF11365.8 EKX46088.1 - 3.1 9.0 11.6 2.6 9.2 1.1 3.0 1 1 1 2 2 2 0 Protein SOGA SNARE PF05739.19 EKX46088.1 - 3.8 7.6 14.0 0.47 10.5 8.0 2.7 3 1 0 3 3 2 0 SNARE domain KxDL PF10241.9 EKX46088.1 - 6.3 7.1 14.7 0.56 10.5 1.5 3.9 3 1 1 4 4 4 0 Uncharacterized conserved protein Spc7 PF08317.11 EKX46088.1 - 8.2 5.2 24.3 0.092 11.6 10.1 2.4 2 1 1 3 3 3 0 Spc7 kinetochore protein NPV_P10 PF05531.12 EKX46088.1 - 9.4 6.8 11.5 19 5.8 1.3 3.8 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein PLU-1 PF08429.11 EKX46089.1 - 0.01 15.0 0.3 0.014 14.6 0.3 1.2 1 0 0 1 1 1 0 PLU-1-like protein ECM11 PF15463.6 EKX46089.1 - 0.036 14.6 0.1 0.074 13.6 0.1 1.5 1 1 0 1 1 1 0 Extracellular mutant protein 11 PI3_PI4_kinase PF00454.27 EKX46090.1 - 3.8e-34 118.6 0.0 2.2e-31 109.6 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Replic_Relax PF13814.6 EKX46090.1 - 0.057 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Replication-relaxation DUF4135 PF13575.6 EKX46090.1 - 0.077 12.3 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) TPR_17 PF13431.6 EKX46091.1 - 3.1e-11 42.8 0.4 1.3 9.6 0.0 5.0 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 EKX46091.1 - 6.2e-11 42.2 1.7 0.047 14.5 0.0 6.5 5 2 1 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX46091.1 - 8.5e-07 29.4 0.3 0.0018 18.7 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX46091.1 - 6.1e-06 26.0 0.8 0.097 12.9 0.0 5.5 5 1 1 6 6 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX46091.1 - 2.8e-05 24.7 0.1 0.36 11.5 0.0 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX46091.1 - 3.3e-05 23.5 0.4 0.032 14.0 0.0 4.4 6 0 0 6 6 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX46091.1 - 7.3e-05 22.8 0.0 0.00075 19.5 0.0 2.8 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 EKX46091.1 - 0.00014 21.5 0.0 0.73 9.6 0.0 4.4 5 0 0 5 5 5 1 TPR repeat TPR_7 PF13176.6 EKX46091.1 - 0.00016 21.5 0.1 3.3 8.0 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX46091.1 - 0.00017 21.4 5.4 0.013 15.5 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX46091.1 - 0.0039 17.4 0.0 0.014 15.6 0.0 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.14 EKX46091.1 - 0.012 15.1 0.0 0.034 13.6 0.0 1.7 2 0 0 2 2 2 0 Coatomer epsilon subunit TPR_12 PF13424.6 EKX46091.1 - 0.024 14.9 4.4 0.56 10.5 0.0 4.2 6 0 0 6 6 6 0 Tetratricopeptide repeat PAN_4 PF14295.6 EKX46092.1 - 3.5e-05 23.6 0.8 0.00014 21.7 0.8 2.0 1 0 0 1 1 1 1 PAN domain Hydrolase_4 PF12146.8 EKX46093.1 - 1.4e-30 106.3 0.0 1.2e-19 70.6 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EKX46093.1 - 2e-05 24.4 0.2 0.024 14.3 0.1 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 EKX46093.1 - 0.052 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EKX46093.1 - 0.09 12.6 0.1 0.56 10.0 0.1 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EKX46093.1 - 0.17 12.5 0.6 1.2 9.7 0.3 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family Pex19 PF04614.12 EKX46095.1 - 7.7e-30 104.5 0.6 8.8e-30 104.3 0.6 1.0 1 0 0 1 1 1 1 Pex19 protein family PPR_2 PF13041.6 EKX46095.1 - 0.15 12.3 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 PPR repeat family NDK PF00334.19 EKX46096.1 - 9.7e-23 80.7 0.0 3.9e-16 59.3 0.0 3.1 3 0 0 3 3 3 2 Nucleoside diphosphate kinase NDK PF00334.19 EKX46097.1 - 4.6e-11 42.9 0.0 4.2e-10 39.8 0.0 2.4 1 1 0 1 1 1 1 Nucleoside diphosphate kinase TPR_2 PF07719.17 EKX46097.1 - 4.1e-06 26.5 0.0 1.1 9.5 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX46097.1 - 2.8e-05 23.7 0.0 0.24 11.3 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX46097.1 - 0.00024 21.6 0.1 0.0019 18.6 0.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX46097.1 - 0.0057 17.4 1.6 5.8 8.0 0.2 3.9 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX46097.1 - 0.012 15.9 0.5 0.77 10.1 0.3 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX46097.1 - 0.13 12.5 0.1 0.4 11.0 0.0 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 EKX46097.1 - 0.86 9.7 2.7 0.68 10.0 0.4 2.0 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 EKX46097.1 - 4.2 7.8 11.0 0.8 10.1 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4766 PF15973.5 EKX46097.1 - 8.7 7.0 16.9 5.9 7.5 11.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4766) SLAIN PF15301.6 EKX46098.1 - 0.0028 17.0 8.1 0.0035 16.7 8.1 1.0 1 0 0 1 1 1 1 SLAIN motif-containing family CSG2 PF16965.5 EKX46098.1 - 0.64 8.9 1.3 0.71 8.8 1.3 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator eIF-3c_N PF05470.12 EKX46098.1 - 1.1 7.5 13.0 1.2 7.4 13.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus YABBY PF04690.13 EKX46098.1 - 1.7 9.2 7.2 2.5 8.6 7.2 1.3 1 0 0 1 1 1 0 YABBY protein CLN3 PF02487.17 EKX46098.1 - 1.9 7.4 3.3 2 7.4 3.3 1.3 1 0 0 1 1 1 0 CLN3 protein Myc_N PF01056.18 EKX46098.1 - 1.9 8.3 16.6 2.1 8.1 16.6 1.3 1 1 0 1 1 1 0 Myc amino-terminal region Sporozoite_P67 PF05642.11 EKX46098.1 - 2.5 6.1 7.6 2.8 5.9 7.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SID-1_RNA_chan PF13965.6 EKX46098.1 - 3.1 6.1 3.4 3.3 6.0 3.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CDC45 PF02724.14 EKX46098.1 - 5.3 5.2 20.8 5.9 5.1 20.8 1.1 1 0 0 1 1 1 0 CDC45-like protein LAP1C PF05609.12 EKX46098.1 - 5.8 5.9 14.8 6.8 5.7 14.8 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) GREB1 PF15782.5 EKX46098.1 - 6.3 3.8 9.9 6.7 3.7 9.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF2151 PF10221.9 EKX46098.1 - 6.8 5.2 11.1 7 5.1 11.1 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator DUF4381 PF14316.6 EKX46099.1 - 1.4 9.1 4.7 0.39 10.9 1.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) POPLD PF08170.12 EKX46100.1 - 1e-18 67.4 0.0 2.3e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 POPLD (NUC188) domain POP1 PF06978.11 EKX46100.1 - 3.3e-06 27.3 16.0 4.4e-06 26.8 2.4 2.9 2 1 1 3 3 3 1 Ribonucleases P/MRP protein subunit POP1 GCV_T_C PF08669.11 EKX46100.1 - 0.00046 20.0 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain GCV_T PF01571.21 EKX46100.1 - 0.015 14.7 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain PsbU PF06514.11 EKX46101.1 - 2.2e-27 94.9 0.4 2.8e-27 94.6 0.4 1.1 1 0 0 1 1 1 1 Photosystem II 12 kDa extrinsic protein (PsbU) HHH_3 PF12836.7 EKX46101.1 - 0.00051 20.2 0.0 0.0011 19.2 0.0 1.6 1 1 0 1 1 1 1 Helix-hairpin-helix motif TAT_signal PF10518.9 EKX46101.1 - 0.001 18.8 0.5 0.0018 18.0 0.5 1.4 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence Glycos_transf_N PF04413.16 EKX46103.1 - 4.6e-35 120.9 0.1 2.6e-34 118.4 0.1 2.0 2 0 0 2 2 2 1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) FliT PF05400.13 EKX46103.1 - 0.067 14.0 0.8 2.5 9.0 0.2 2.5 2 0 0 2 2 2 0 Flagellar protein FliT DSPc PF00782.20 EKX46104.1 - 4.2e-28 97.8 0.1 6.8e-28 97.1 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EKX46104.1 - 0.00056 20.1 0.0 0.0017 18.5 0.0 1.9 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 EKX46104.1 - 0.001 18.7 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase zf-BED PF02892.15 EKX46104.1 - 0.017 15.2 0.0 0.046 13.8 0.0 1.7 1 0 0 1 1 1 0 BED zinc finger DUF2155 PF09923.9 EKX46104.1 - 0.12 12.7 0.6 0.49 10.7 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2155) DUF445 PF04286.12 EKX46106.1 - 0.21 11.4 1.8 0.29 10.9 0.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF445) TPX2_importin PF12214.8 EKX46107.1 - 4.1e-27 95.4 89.4 2.2e-15 57.2 6.2 9.5 5 2 3 8 8 8 6 Cell cycle regulated microtubule associated protein TPX2 PF06886.11 EKX46107.1 - 3.9e-12 46.2 20.8 3.9e-12 46.2 20.8 6.9 8 0 0 8 8 8 2 Targeting protein for Xklp2 (TPX2) Kinesin PF00225.23 EKX46108.1 - 8.6e-96 320.8 0.3 1e-95 320.5 0.3 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX46108.1 - 9.3e-31 106.8 0.1 1.8e-30 105.8 0.1 1.5 1 0 0 1 1 1 1 Microtubule binding COBRA1 PF06209.13 EKX46109.1 - 3e-12 46.2 0.3 7.9e-12 44.8 0.0 1.8 2 0 0 2 2 2 1 Cofactor of BRCA1 (COBRA1) DUF5631 PF18645.1 EKX46109.1 - 0.028 14.8 0.0 0.088 13.2 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5631) YycH PF07435.11 EKX46109.1 - 0.064 12.2 0.3 0.18 10.8 0.0 1.8 2 0 0 2 2 2 0 YycH protein Syntaxin_2 PF14523.6 EKX46109.1 - 0.38 11.2 5.0 5.7 7.4 0.7 3.2 3 0 0 3 3 3 0 Syntaxin-like protein JIP_LZII PF16471.5 EKX46109.1 - 0.97 9.7 7.5 10 6.4 1.3 2.8 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Alpha_kinase PF02816.18 EKX46110.1 - 3.1e-41 141.5 0.0 3.6e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 Alpha-kinase family DUF4772 PF15997.5 EKX46111.1 - 0.014 16.0 0.5 0.019 15.6 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4772) Pkinase PF00069.25 EKX46113.1 - 3.6e-17 62.6 0.1 7.5e-15 55.0 0.0 2.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX46113.1 - 5.3e-07 29.2 0.0 8.7e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX46113.1 - 6.2e-05 22.4 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EKX46113.1 - 0.00077 18.3 0.0 0.0013 17.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX46113.1 - 0.0085 16.0 0.0 0.016 15.1 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EKX46113.1 - 0.041 13.4 0.0 0.066 12.7 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DnaJ PF00226.31 EKX46114.1 - 1.1e-15 57.5 0.7 2.2e-15 56.5 0.7 1.5 1 0 0 1 1 1 1 DnaJ domain EF-hand_1 PF00036.32 EKX46115.1 - 4.1e-11 41.6 12.0 0.0038 16.7 0.0 5.0 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EKX46115.1 - 1.9e-07 30.4 8.4 0.068 13.1 0.1 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 EKX46115.1 - 1.7e-06 28.3 10.3 0.00041 20.7 1.7 3.4 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EKX46115.1 - 4.7e-06 25.8 10.6 0.019 14.4 0.1 4.8 5 0 0 5 5 5 2 EF hand Methyltransf_34 PF11312.8 EKX46115.1 - 0.0086 15.4 0.0 0.12 11.6 0.0 2.1 1 1 0 1 1 1 1 Putative SAM-dependent methyltransferase EF-hand_8 PF13833.6 EKX46115.1 - 0.012 15.5 5.9 1.7 8.5 0.5 3.5 3 0 0 3 3 3 0 EF-hand domain pair Rpn9_C PF18261.1 EKX46115.1 - 0.035 13.7 0.4 0.075 12.6 0.4 1.5 1 0 0 1 1 1 0 Rpn9 C-terminal helix FGGY_N PF00370.21 EKX46117.1 - 2.4e-42 145.2 0.0 4e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EKX46117.1 - 2.1e-33 115.7 0.3 3.2e-33 115.1 0.3 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain HSP70 PF00012.20 EKX46117.1 - 0.099 10.8 0.0 0.15 10.2 0.0 1.1 1 0 0 1 1 1 0 Hsp70 protein PEMT PF04191.13 EKX46120.1 - 7.7e-13 48.8 0.6 1.1e-12 48.3 0.6 1.2 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 EKX46120.1 - 0.00011 22.5 0.1 0.0002 21.7 0.1 1.5 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Zip PF02535.22 EKX46121.1 - 1.1e-46 159.6 13.0 1.4e-46 159.3 13.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF373 PF04123.13 EKX46121.1 - 0.93 8.9 8.5 0.32 10.4 1.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF373) PhyH PF05721.13 EKX46123.1 - 1.3e-19 71.3 0.3 2e-19 70.7 0.3 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Imm30 PF15565.6 EKX46124.1 - 0.1 12.7 0.6 0.25 11.4 0.6 1.6 1 0 0 1 1 1 0 Immunity protein 30 PsbQ PF05757.11 EKX46125.1 - 0.2 11.4 4.5 0.068 12.9 2.0 1.6 1 1 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) PhyH PF05721.13 EKX46126.1 - 1.4e-13 51.6 0.2 5e-07 30.2 0.1 3.2 2 1 0 3 3 3 3 Phytanoyl-CoA dioxygenase (PhyH) Sulfotransfer_3 PF13469.6 EKX46127.1 - 0.0036 17.7 0.0 2.3 8.5 0.0 3.2 2 1 1 3 3 3 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 EKX46127.1 - 0.09 12.2 0.1 0.65 9.4 0.0 2.3 2 1 0 2 2 2 0 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EKX46128.1 - 0.0027 18.1 0.0 1.2 9.5 0.0 2.4 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 EKX46128.1 - 0.028 13.9 0.1 0.33 10.4 0.0 2.5 2 1 0 2 2 2 0 Sulfotransferase domain RWP-RK PF02042.15 EKX46129.1 - 5e-13 48.8 2.0 6.5e-13 48.4 0.3 2.1 2 0 0 2 2 2 1 RWP-RK domain YL1_C PF08265.11 EKX46130.1 - 3.2e-07 30.0 0.5 6.3e-07 29.1 0.5 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Agenet PF05641.12 EKX46130.1 - 5.6e-05 23.5 0.1 0.0001 22.7 0.1 1.4 1 0 0 1 1 1 1 Agenet domain Tudor_4 PF18358.1 EKX46130.1 - 0.00017 21.1 0.3 0.00027 20.5 0.3 1.3 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain PRCH PF03967.13 EKX46130.1 - 0.034 14.4 0.1 0.044 14.0 0.1 1.3 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region DUF2117 PF09890.9 EKX46130.1 - 0.049 13.1 0.1 0.054 12.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2117) DUF1580 PF07618.11 EKX46132.1 - 0.022 14.4 0.7 52 3.6 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1580) DUF4483 PF14825.6 EKX46132.1 - 0.045 13.5 0.0 69 3.2 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4483) EF-hand_4 PF12763.7 EKX46132.1 - 0.097 12.6 0.0 94 3.0 0.0 3.1 3 0 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand VirionAssem_T7 PF11653.8 EKX46132.1 - 0.13 12.8 9.2 18 5.9 0.3 3.3 3 0 0 3 3 3 0 Bacteriophage T7 virion assembly protein RVT_1 PF00078.27 EKX46133.1 - 5.3e-06 26.1 7.5 5.8e-05 22.7 0.0 2.9 2 1 1 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) ORC5_C PF14630.6 EKX46133.1 - 0.043 13.3 0.1 0.043 13.3 0.1 4.5 2 1 2 4 4 4 0 Origin recognition complex (ORC) subunit 5 C-terminus Polyketide_cyc2 PF10604.9 EKX46135.1 - 4.2e-12 46.5 0.2 6.3e-12 46.0 0.2 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EKX46135.1 - 5.4e-12 46.0 0.0 8.8e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport EF-hand_1 PF00036.32 EKX46137.1 - 8.3e-35 115.7 18.7 3e-09 35.8 1.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EKX46137.1 - 2.6e-31 107.9 10.2 6.9e-17 61.7 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX46137.1 - 5.9e-28 94.4 9.8 2.9e-09 36.1 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EKX46137.1 - 8e-27 92.9 14.8 7.9e-13 48.1 1.2 3.6 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EKX46137.1 - 1.5e-18 65.4 17.6 8.2e-06 25.1 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EKX46137.1 - 6.3e-15 55.3 0.3 7.2e-07 29.4 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EKX46137.1 - 1.3e-06 28.3 7.9 0.11 12.4 0.7 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EKX46137.1 - 3.7e-05 24.0 1.2 0.067 13.5 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 EKX46137.1 - 0.00051 20.3 1.4 0.15 12.4 0.3 2.6 1 1 1 2 2 2 1 EF-hand domain SurA_N_3 PF13624.6 EKX46137.1 - 0.0006 19.6 3.4 0.085 12.6 0.8 2.2 2 1 0 2 2 2 2 SurA N-terminal domain FlgD PF03963.14 EKX46137.1 - 0.0021 18.3 0.1 0.0034 17.7 0.1 1.5 1 1 0 1 1 1 1 Flagellar hook capping protein - N-terminal region SurA_N_2 PF13623.6 EKX46137.1 - 0.0022 17.9 6.4 0.39 10.6 1.2 3.0 1 1 1 2 2 2 2 SurA N-terminal domain SUB1_ProdP9 PF18213.1 EKX46137.1 - 0.0027 17.5 1.0 0.0081 16.0 0.2 2.0 2 0 0 2 2 2 1 SUB1 protease Prodomain ProdP9 Dockerin_1 PF00404.18 EKX46137.1 - 0.003 17.7 0.2 2.3 8.5 0.0 2.4 2 0 0 2 2 2 2 Dockerin type I domain Cas9_REC PF16592.5 EKX46137.1 - 0.0076 15.0 3.0 0.0093 14.7 3.0 1.2 1 0 0 1 1 1 1 REC lobe of CRISPR-associated endonuclease Cas9 Sigma54_CBD PF04963.13 EKX46137.1 - 0.012 15.5 0.4 0.016 15.0 0.4 1.1 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain Caleosin PF05042.13 EKX46137.1 - 0.015 15.2 1.0 11 5.9 0.0 3.4 1 1 3 4 4 4 0 Caleosin related protein PMBR PF09373.10 EKX46137.1 - 0.047 13.9 0.4 46 4.4 0.0 3.8 4 0 0 4 4 4 0 Pseudomurein-binding repeat Staphylokinase PF02821.16 EKX46137.1 - 0.052 14.0 0.8 0.62 10.5 0.6 2.4 1 1 2 3 3 3 0 Staphylokinase/Streptokinase family DUF3008 PF11450.8 EKX46137.1 - 0.081 13.1 0.2 0.081 13.1 0.2 2.5 4 0 0 4 4 2 0 Protein of unknwon function (DUF3008) EF-hand_11 PF08976.11 EKX46137.1 - 0.13 13.1 0.3 20 6.1 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain Phg_2220_C PF09524.10 EKX46137.1 - 0.21 11.7 1.7 4.5 7.4 0.1 2.5 2 1 1 3 3 2 0 Conserved phage C-terminus (Phg_2220_C) MgtE_N PF03448.17 EKX46137.1 - 0.27 11.9 5.4 0.087 13.4 1.0 2.3 2 1 1 3 3 3 0 MgtE intracellular N domain MazG PF03819.17 EKX46137.1 - 0.29 11.4 4.0 2.6 8.3 0.0 3.0 2 1 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain YolD PF08863.10 EKX46137.1 - 0.72 9.9 5.4 15 5.7 0.2 3.2 3 1 0 3 3 3 0 YolD-like protein Styelin PF17562.2 EKX46137.1 - 3.7 8.0 7.8 1.2 9.5 2.9 2.6 2 2 1 3 3 3 0 Styelin Ion_trans_2 PF07885.16 EKX46138.1 - 1.4e-14 53.8 1.4 1.5e-14 53.7 1.4 1.0 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EKX46138.1 - 4e-06 26.3 3.2 4.1e-06 26.2 3.2 1.0 1 0 0 1 1 1 1 Ion transport protein PH PF00169.29 EKX46139.1 - 5.9e-07 30.0 0.4 1.1e-06 29.1 0.4 1.5 1 0 0 1 1 1 1 PH domain PH_6 PF15406.6 EKX46139.1 - 0.037 14.3 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 EKX46139.1 - 0.088 13.2 1.3 0.87 10.0 1.3 2.3 1 1 0 1 1 1 0 Pleckstrin homology domain cNMP_binding PF00027.29 EKX46140.1 - 5.2e-11 42.5 0.2 1.2e-10 41.4 0.2 1.6 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain Laminin_G_3 PF13385.6 EKX46141.1 - 1.6e-05 25.1 2.2 1.4 9.1 0.3 3.8 3 1 0 3 3 3 3 Concanavalin A-like lectin/glucanases superfamily His_Phos_2 PF00328.22 EKX46142.1 - 0.0014 18.1 0.6 0.0019 17.6 0.6 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Methyltransf_32 PF13679.6 EKX46142.1 - 0.0036 17.3 0.8 0.0052 16.8 0.8 1.2 1 0 0 1 1 1 1 Methyltransferase domain AAA_23 PF13476.6 EKX46142.1 - 0.043 14.3 4.8 0.053 14.0 4.8 1.1 1 0 0 1 1 1 0 AAA domain Dynactin_p62 PF05502.13 EKX46142.1 - 0.16 10.7 6.1 0.21 10.3 6.1 1.1 1 0 0 1 1 1 0 Dynactin p62 family Connexin PF00029.19 EKX46142.1 - 1.1 8.9 4.6 1.7 8.4 4.6 1.2 1 0 0 1 1 1 0 Connexin S6OS1 PF15676.5 EKX46143.1 - 0.095 11.2 7.9 0.12 10.8 7.9 1.1 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family PDEase_I PF00233.19 EKX46145.1 - 2.1e-78 263.3 0.6 2.5e-78 263.1 0.6 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF5314 PF17241.2 EKX46146.1 - 0.0024 17.6 0.0 0.0045 16.7 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5314) SPX PF03105.19 EKX46147.1 - 0.017 15.0 0.0 0.032 14.2 0.0 1.5 1 1 0 1 1 1 0 SPX domain Thioredoxin PF00085.20 EKX46148.1 - 1.1e-28 99.2 0.0 1.6e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EKX46148.1 - 5.8e-06 26.7 0.1 1.7e-05 25.2 0.0 1.8 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_6 PF13848.6 EKX46148.1 - 6.4e-05 22.9 0.1 0.00012 22.1 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like domain ERp29 PF07749.12 EKX46148.1 - 0.00017 22.5 0.3 0.00025 21.9 0.3 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 EKX46148.1 - 0.00022 20.7 0.0 0.00027 20.4 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EKX46148.1 - 0.018 15.4 0.1 3.8 7.9 0.0 2.8 2 1 1 3 3 3 0 Thioredoxin-like DUF2497 PF10691.9 EKX46148.1 - 0.057 13.9 0.0 0.12 12.8 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) Thioredoxin_7 PF13899.6 EKX46148.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like DUF3593 PF12159.8 EKX46149.1 - 1.1e-27 95.8 0.2 1.3e-27 95.6 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3593) DUF2499 PF10693.9 EKX46150.1 - 2e-33 114.5 0.7 2.3e-33 114.3 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2499) cNMP_binding PF00027.29 EKX46152.1 - 1.6e-08 34.5 0.2 1.9e-07 31.0 0.1 2.1 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain RAP1 PF07218.11 EKX46152.1 - 2 6.6 4.2 2.3 6.4 4.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase PF00069.25 EKX46153.1 - 6.7e-72 242.0 0.0 7.7e-72 241.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX46153.1 - 8e-36 123.6 0.0 9.8e-36 123.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX46153.1 - 2.1e-05 24.0 0.0 3.4e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EKX46153.1 - 0.011 15.1 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SRP54 PF00448.22 EKX46153.1 - 0.077 12.6 0.2 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain BIR PF00653.21 EKX46154.1 - 1.7e-21 76.7 0.1 1.1e-19 70.9 0.0 2.3 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain zf-C3HC PF07967.13 EKX46154.1 - 6.9e-05 22.9 0.0 0.00027 21.0 0.0 2.0 2 2 0 2 2 2 1 C3HC zinc finger-like APG6_N PF17675.1 EKX46154.1 - 0.18 12.4 12.4 0.42 11.2 5.2 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region SOGA PF11365.8 EKX46154.1 - 0.61 11.2 8.9 0.15 13.2 1.7 2.5 2 1 0 2 2 2 0 Protein SOGA Nif11 PF07862.11 EKX46154.1 - 1.6 9.1 7.8 1.5 9.2 1.3 3.6 3 1 0 3 3 3 0 Nif11 domain TRAF_BIRC3_bd PF16673.5 EKX46154.1 - 5.4 6.9 6.4 1.7 8.5 0.7 2.3 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain ABC_tran_CTD PF16326.5 EKX46154.1 - 5.9 7.2 16.2 0.28 11.5 1.5 3.4 2 2 2 4 4 4 0 ABC transporter C-terminal domain CREPT PF16566.5 EKX46154.1 - 7.2 6.8 9.7 0.32 11.2 2.2 2.0 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour TMF_DNA_bd PF12329.8 EKX46154.1 - 8.6 6.4 16.0 10 6.2 2.7 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Ion_trans PF00520.31 EKX46155.1 - 1.1e-32 113.2 17.4 1.7e-32 112.6 17.4 1.3 1 0 0 1 1 1 1 Ion transport protein EF-hand_1 PF00036.32 EKX46155.1 - 3.6e-14 51.2 3.9 0.00034 19.9 0.0 4.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EKX46155.1 - 1.1e-11 43.7 0.7 0.035 14.0 0.0 4.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 EKX46155.1 - 1.3e-09 38.3 1.8 7.7e-05 23.1 0.0 3.4 2 1 1 3 3 3 3 EF-hand domain pair PKD_channel PF08016.12 EKX46155.1 - 8.6e-07 28.0 13.6 3.2e-05 22.8 7.5 2.2 1 1 1 2 2 2 2 Polycystin cation channel EF-hand_5 PF13202.6 EKX46155.1 - 7.9e-06 25.1 3.8 0.081 12.4 0.3 3.9 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EKX46155.1 - 0.00013 21.8 4.6 6.4 6.7 0.1 5.0 5 1 0 5 5 5 2 EF-hand domain pair FmiP_Thoc5 PF09766.9 EKX46156.1 - 0.00036 19.9 1.3 0.00081 18.8 1.3 1.5 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 dsRBD2 PF17842.1 EKX46157.1 - 0.086 13.0 3.4 0.24 11.6 3.4 1.8 1 1 0 1 1 1 0 Double-stranded RNA binding domain 2 MGAT2 PF05060.14 EKX46158.1 - 1.2e-25 90.4 3.7 1.6e-16 60.3 0.3 2.4 1 1 1 2 2 2 2 N-acetylglucosaminyltransferase II (MGAT2) DUF4214 PF13946.6 EKX46158.1 - 8.9e-08 32.1 0.3 0.012 15.6 0.0 3.2 2 1 1 3 3 3 2 Domain of unknown function (DUF4214) PBS_linker_poly PF00427.21 EKX46158.1 - 0.0018 18.3 0.1 0.6 10.2 0.0 3.1 2 1 0 2 2 2 1 Phycobilisome Linker polypeptide Toxin_38 PF14866.6 EKX46158.1 - 0.68 10.3 2.5 4.5 7.6 0.1 2.5 2 0 0 2 2 2 0 Potassium channel toxin Pkinase PF00069.25 EKX46159.1 - 3.1e-28 98.9 0.0 4.3e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX46159.1 - 1.1e-07 31.4 0.0 1.4e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX46159.1 - 0.0055 16.1 0.0 0.0095 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX46159.1 - 0.064 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Robl_LC7 PF03259.17 EKX46160.1 - 1.3e-05 24.9 0.0 1.8e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Roadblock/LC7 domain Peptidase_M11 PF05548.11 EKX46160.1 - 0.19 10.8 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Gametolysin peptidase M11 Asp-B-Hydro_N PF05279.11 EKX46161.1 - 2.9 7.9 47.5 5.5 7.0 47.5 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Borrelia_P83 PF05262.11 EKX46161.1 - 7.6 4.9 38.5 10 4.5 38.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Vps51 PF08700.11 EKX46163.1 - 1.3e-26 92.5 0.5 5.4e-26 90.5 0.5 2.1 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 EKX46163.1 - 1.9e-11 43.3 0.7 1.9e-11 43.3 0.7 2.0 2 0 0 2 2 2 1 Dor1-like family Sec5 PF15469.6 EKX46163.1 - 9.5e-09 35.3 0.2 4.7e-08 33.1 0.2 2.2 2 0 0 2 2 2 1 Exocyst complex component Sec5 COG2 PF06148.11 EKX46163.1 - 1.3e-08 35.0 0.3 1.3e-08 35.0 0.3 3.7 3 1 1 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 EKX46163.1 - 2.2e-08 34.4 0.4 2.2e-08 34.4 0.4 2.4 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Zw10 PF06248.13 EKX46163.1 - 2.7e-05 23.0 0.8 5e-05 22.1 0.8 1.4 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Vps54_N PF10475.9 EKX46163.1 - 0.00068 19.0 0.1 0.0021 17.4 0.1 1.8 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex CENP-F_leu_zip PF10473.9 EKX46163.1 - 0.00092 19.2 16.5 0.0042 17.1 1.5 3.0 3 0 0 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Gp-FAR-1 PF05823.12 EKX46163.1 - 0.03 14.7 0.8 0.47 10.8 0.1 2.5 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Spc7 PF08317.11 EKX46163.1 - 0.044 12.7 0.1 0.044 12.7 0.1 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 EKX46163.1 - 2.9 8.6 11.3 0.71 10.5 0.4 4.1 4 0 0 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Thioredoxin PF00085.20 EKX46164.1 - 1.8e-25 88.9 0.1 2.4e-25 88.5 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EKX46164.1 - 8.5e-10 39.1 0.0 3e-09 37.3 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 EKX46164.1 - 8e-07 29.1 0.0 9.5e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 EKX46164.1 - 6.8e-06 26.2 0.0 1e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 EKX46164.1 - 9.6e-05 22.6 0.1 0.00072 19.8 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EKX46164.1 - 0.0035 17.3 0.0 0.0045 16.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EKX46164.1 - 0.009 15.7 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Redoxin Thioredox_DsbH PF03190.15 EKX46164.1 - 0.01 15.8 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 HyaE PF07449.11 EKX46164.1 - 0.049 13.6 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DIM1 PF02966.16 EKX46164.1 - 0.12 12.2 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 OST3_OST6 PF04756.13 EKX46164.1 - 0.15 11.4 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Chloroa_b-bind PF00504.21 EKX46165.1 - 7.1e-39 133.9 0.4 9.1e-39 133.6 0.4 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein PGA_cap PF09587.10 EKX46165.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap AAA PF00004.29 EKX46166.1 - 5.5e-36 123.9 0.0 7.7e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EKX46166.1 - 4.5e-10 39.2 0.0 1.5e-09 37.5 0.0 1.8 2 0 0 2 2 1 1 AAA+ lid domain RuvB_N PF05496.12 EKX46166.1 - 2e-07 30.9 0.0 2.9e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 EKX46166.1 - 2.6e-06 27.3 0.0 4.2e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EKX46166.1 - 5.7e-06 26.1 0.0 0.15 11.7 0.0 3.1 2 1 1 3 3 3 1 Sigma-54 interaction domain AAA_5 PF07728.14 EKX46166.1 - 1.6e-05 24.9 0.0 4e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EKX46166.1 - 4.6e-05 23.7 0.8 0.0015 18.8 0.4 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EKX46166.1 - 5.2e-05 23.7 0.1 0.00092 19.6 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EKX46166.1 - 5.3e-05 23.3 0.0 7.9e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 EKX46166.1 - 8.4e-05 21.9 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 EKX46166.1 - 0.00036 20.1 0.0 0.00066 19.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 EKX46166.1 - 0.00048 20.1 0.2 0.011 15.6 0.1 2.5 1 1 1 2 2 2 1 NACHT domain Mg_chelatase PF01078.21 EKX46166.1 - 0.00066 19.1 0.0 0.0014 18.1 0.0 1.5 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EKX46166.1 - 0.00076 19.8 0.0 0.0015 18.9 0.0 1.6 1 1 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 EKX46166.1 - 0.0012 19.3 0.2 0.0034 17.9 0.2 1.9 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EKX46166.1 - 0.0014 18.4 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 EKX46166.1 - 0.0019 18.4 0.0 0.0036 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EKX46166.1 - 0.0021 18.2 0.0 0.0049 17.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EKX46166.1 - 0.0023 17.5 0.2 0.0047 16.5 0.1 1.6 2 0 0 2 2 1 1 AAA domain ATPase PF06745.13 EKX46166.1 - 0.0055 16.1 0.2 0.43 9.9 0.1 2.3 1 1 1 2 2 2 1 KaiC NB-ARC PF00931.22 EKX46166.1 - 0.0079 15.4 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Parvo_NS1 PF01057.17 EKX46166.1 - 0.014 14.5 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TsaE PF02367.17 EKX46166.1 - 0.018 15.0 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EKX46166.1 - 0.023 14.9 0.0 0.058 13.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain DUF815 PF05673.13 EKX46166.1 - 0.025 13.7 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 EKX46166.1 - 0.033 14.7 0.0 0.045 14.3 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Bac_DnaA PF00308.18 EKX46166.1 - 0.037 13.9 0.1 0.18 11.6 0.1 1.9 1 1 0 1 1 1 0 Bacterial dnaA protein PhoH PF02562.16 EKX46166.1 - 0.043 13.3 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Guanylate_kin PF00625.21 EKX46166.1 - 0.044 13.5 0.0 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 Guanylate kinase Sigma54_activ_2 PF14532.6 EKX46166.1 - 0.048 13.8 0.0 0.099 12.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 EKX46166.1 - 0.052 13.4 0.0 0.12 12.2 0.0 1.6 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 EKX46166.1 - 0.086 13.3 0.1 0.17 12.3 0.0 1.6 2 1 0 2 2 1 0 AAA domain AAA_30 PF13604.6 EKX46166.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EKX46166.1 - 0.1 12.5 0.1 0.62 9.9 0.0 1.9 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EKX46166.1 - 0.16 12.3 0.4 0.47 10.8 0.2 1.9 2 1 0 2 2 1 0 AAA domain AAA_11 PF13086.6 EKX46166.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain CPT PF07931.12 EKX46166.1 - 0.18 11.7 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF2075 PF09848.9 EKX46166.1 - 0.24 10.6 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Aminotran_1_2 PF00155.21 EKX46167.1 - 1e-42 146.7 0.0 1.3e-42 146.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EKX46167.1 - 0.00095 18.5 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase ABC_transp_aux PF09822.9 EKX46167.1 - 0.023 14.2 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 ABC-type uncharacterized transport system Adhesin_P1_N PF18652.1 EKX46167.1 - 0.044 13.8 0.1 0.85 9.7 0.0 2.5 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain VRP3 PF03536.15 EKX46167.1 - 0.068 12.7 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Salmonella virulence-associated 28kDa protein GSHPx PF00255.19 EKX46169.1 - 0.1 12.2 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Glutathione peroxidase PDZ_6 PF17820.1 EKX46170.1 - 5.2e-08 32.6 0.1 1.1e-07 31.6 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX46170.1 - 2.2e-05 24.7 0.0 3.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX46170.1 - 0.02 15.2 0.0 0.044 14.1 0.0 1.6 1 0 0 1 1 1 0 PDZ domain DUF2408 PF10303.9 EKX46170.1 - 0.022 15.3 2.4 0.047 14.2 2.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) OmpH PF03938.14 EKX46170.1 - 0.028 14.8 1.0 0.048 14.0 1.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF5339 PF17274.2 EKX46170.1 - 0.12 13.2 0.1 0.28 12.1 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5339) Mito_carr PF00153.27 EKX46171.1 - 5.2e-24 84.0 2.6 2.5e-13 49.7 0.2 3.1 2 1 0 2 2 2 2 Mitochondrial carrier protein Peptidase_M13_N PF05649.13 EKX46172.1 - 5.6e-51 174.4 0.0 1.1e-29 104.3 0.0 3.1 1 1 1 2 2 2 2 Peptidase family M13 Peptidase_M13 PF01431.21 EKX46172.1 - 3.4e-23 82.3 1.2 8.6e-20 71.2 0.0 3.3 2 1 1 3 3 3 3 Peptidase family M13 Ribosomal_S25 PF03297.15 EKX46173.1 - 1.8e-39 134.0 5.3 2.3e-39 133.7 5.3 1.1 1 0 0 1 1 1 1 S25 ribosomal protein EloA-BP1 PF15870.5 EKX46173.1 - 0.011 16.0 1.0 0.017 15.3 1.0 1.3 1 0 0 1 1 1 0 ElonginA binding-protein 1 RPA_C PF08784.11 EKX46173.1 - 0.021 15.5 0.0 0.028 15.1 0.0 1.1 1 0 0 1 1 1 0 Replication protein A C terminal Tctex-1 PF03645.13 EKX46173.1 - 0.029 14.6 0.1 0.039 14.2 0.1 1.2 1 0 0 1 1 1 0 Tctex-1 family ABC_export PF16962.5 EKX46173.1 - 0.46 8.9 3.6 0.5 8.8 3.6 1.1 1 0 0 1 1 1 0 Putative ABC exporter DUF4854 PF16146.5 EKX46174.1 - 0.093 13.1 0.8 34 4.8 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4854) COG5 PF10392.9 EKX46174.1 - 0.6 10.3 9.6 0.84 9.8 0.9 2.9 3 0 0 3 3 3 0 Golgi transport complex subunit 5 DUF4407 PF14362.6 EKX46174.1 - 0.78 9.0 7.7 3.3 7.0 6.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 EKX46174.1 - 1.6 9.0 9.7 3.3 8.0 0.1 2.7 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 DUF4618 PF15397.6 EKX46174.1 - 3 7.2 10.3 4.6 6.6 1.6 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) bZIP_1 PF00170.21 EKX46174.1 - 7.5 6.7 13.7 0.12 12.4 1.8 3.1 3 0 0 3 3 3 0 bZIP transcription factor PHY PF00360.20 EKX46175.1 - 7.8e-36 123.1 0.0 1.8e-35 121.9 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region GAF PF01590.26 EKX46175.1 - 5.9e-17 62.5 0.0 1.2e-16 61.6 0.0 1.5 1 0 0 1 1 1 1 GAF domain PAS_2 PF08446.11 EKX46175.1 - 3.6e-15 56.5 0.1 2.1e-13 50.9 0.0 2.6 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 EKX46175.1 - 7.9e-15 54.8 0.0 1.3e-09 38.1 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 EKX46175.1 - 1e-06 29.0 0.0 0.00048 20.4 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 EKX46175.1 - 1.1e-05 25.7 0.0 0.0018 18.5 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 EKX46175.1 - 0.016 15.5 0.0 0.73 10.2 0.0 2.7 2 0 0 2 2 2 0 PAS fold PAS_8 PF13188.7 EKX46175.1 - 0.022 14.8 0.0 0.27 11.3 0.0 2.7 2 0 0 2 2 2 0 PAS domain WIYLD PF10440.9 EKX46175.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain Pkinase PF00069.25 EKX46176.1 - 1.9e-51 175.0 0.1 2.1e-51 174.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX46176.1 - 9e-33 113.6 0.1 1.1e-32 113.4 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX46176.1 - 1.2e-06 28.0 0.1 1.6e-06 27.7 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX46176.1 - 0.00019 21.5 0.1 0.00056 19.9 0.1 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 EKX46176.1 - 0.00075 18.6 0.0 0.001 18.2 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 EKX46176.1 - 0.0021 17.1 0.0 0.0025 16.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EKX46176.1 - 0.0023 17.3 0.0 0.0061 15.9 0.0 1.6 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 EKX46176.1 - 0.0097 15.5 0.1 0.014 15.0 0.1 1.2 1 0 0 1 1 1 1 RIO1 family DUF3819 PF12842.7 EKX46176.1 - 0.053 13.5 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3819) SAM_1 PF00536.30 EKX46177.1 - 3.1e-07 30.7 0.1 5.2e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EKX46177.1 - 7.1e-05 22.8 0.1 0.00014 21.9 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) U1snRNP70_N PF12220.8 EKX46177.1 - 0.077 13.6 0.0 0.29 11.8 0.0 1.9 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4164 PF13747.6 EKX46177.1 - 6.6 7.1 10.3 0.52 10.6 4.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) PDZ_6 PF17820.1 EKX46178.1 - 1.8e-09 37.3 2.9 5.5e-08 32.5 2.9 2.8 1 1 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX46178.1 - 1.4e-06 28.6 0.0 6.7e-06 26.3 0.0 2.1 1 1 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX46178.1 - 0.02 14.9 0.0 0.053 13.5 0.0 1.7 1 0 0 1 1 1 0 Tricorn protease PDZ domain DASH_Dad3 PF08656.10 EKX46178.1 - 0.15 12.2 2.1 6.8 6.9 0.1 2.8 2 0 0 2 2 2 0 DASH complex subunit Dad3 Snapin_Pallidin PF14712.6 EKX46178.1 - 1.2 9.6 17.4 0.048 14.1 6.1 3.1 3 0 0 3 3 3 0 Snapin/Pallidin HEAT PF02985.22 EKX46178.1 - 2.6 8.5 4.9 18 6.0 0.1 3.7 3 0 0 3 3 3 0 HEAT repeat DivIVA PF05103.13 EKX46178.1 - 3.7 7.6 11.0 3.3 7.8 3.0 3.5 3 0 0 3 3 3 0 DivIVA protein Sugarporin_N PF11471.8 EKX46178.1 - 4.5 7.3 8.1 1.2 9.1 0.8 3.2 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension RNase_Zc3h12a PF11977.8 EKX46179.1 - 1.4e-16 60.7 0.0 2.5e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain Pox_RNA_Pol_19 PF05320.12 EKX46179.1 - 0.4 10.6 5.8 1 9.3 5.8 1.6 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit RRN3 PF05327.11 EKX46179.1 - 0.87 8.1 11.1 1.5 7.3 11.1 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Astro_capsid_p PF12226.8 EKX46179.1 - 4.1 6.4 8.3 7.1 5.7 8.3 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Gemin6 PF06372.12 EKX46180.1 - 1.1e-11 44.5 0.0 1.5e-11 44.1 0.0 1.0 1 0 0 1 1 1 1 Gemin6 protein Cadherin_4 PF17803.1 EKX46180.1 - 0.17 12.5 0.0 0.4 11.3 0.0 1.6 1 1 0 1 1 1 0 Bacterial cadherin-like domain cNMP_binding PF00027.29 EKX46181.1 - 9.9e-21 73.6 0.4 4.7e-10 39.4 0.1 3.7 2 2 0 2 2 2 2 Cyclic nucleotide-binding domain C1q PF00386.21 EKX46181.1 - 0.037 14.3 0.0 0.076 13.2 0.0 1.4 1 0 0 1 1 1 0 C1q domain DUF4826 PF16108.5 EKX46181.1 - 0.1 12.9 0.0 11 6.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4826) Myosin_head PF00063.21 EKX46182.1 - 6.6e-05 21.3 0.0 0.013 13.8 0.0 2.2 2 0 0 2 2 2 2 Myosin head (motor domain) WD40 PF00400.32 EKX46183.1 - 6.8e-48 159.7 25.3 6.7e-10 39.4 0.8 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX46183.1 - 3.7e-10 40.0 1.7 0.0012 19.1 0.0 5.3 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX46183.1 - 4.6e-05 22.5 6.3 0.014 14.4 0.8 4.2 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EKX46183.1 - 0.00013 20.8 10.4 0.018 13.7 0.1 5.0 3 2 2 5 5 5 2 Nucleoporin Nup120/160 IKI3 PF04762.12 EKX46183.1 - 0.085 10.8 0.0 1.4 6.8 0.0 2.1 2 0 0 2 2 2 0 IKI3 family YdjO PF14169.6 EKX46183.1 - 1.1 9.1 4.9 0.65 9.8 0.3 2.8 3 0 0 3 3 3 0 Cold-inducible protein YdjO HATPase_c PF02518.26 EKX46184.1 - 2.4e-25 89.2 0.0 4.4e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EKX46184.1 - 1.9e-16 59.8 0.5 4.5e-16 58.6 0.5 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.24 EKX46184.1 - 2.8e-12 46.8 1.2 7e-12 45.5 1.2 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Bac_rhodopsin PF01036.18 EKX46184.1 - 2.5e-10 40.3 19.2 3.9e-10 39.7 19.2 1.2 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein HATPase_c_5 PF14501.6 EKX46184.1 - 0.0022 17.9 0.0 0.0062 16.4 0.0 1.7 1 0 0 1 1 1 1 GHKL domain HATPase_c_3 PF13589.6 EKX46184.1 - 0.0035 17.2 0.0 0.0088 15.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EKX46184.1 - 0.014 15.4 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain PDZ_6 PF17820.1 EKX46187.1 - 2.5e-07 30.4 0.3 4.2e-07 29.7 0.3 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX46187.1 - 0.0005 20.4 0.2 0.00094 19.5 0.2 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX46187.1 - 0.00058 20.1 0.1 0.00099 19.4 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Pribosyltran PF00156.27 EKX46187.1 - 0.022 14.2 0.1 0.03 13.8 0.1 1.4 1 1 0 1 1 1 0 Phosphoribosyl transferase domain E7 PF00527.18 EKX46187.1 - 0.19 12.0 1.6 0.29 11.4 1.6 1.4 1 0 0 1 1 1 0 E7 protein, Early protein DUF3682 PF12446.8 EKX46187.1 - 0.55 10.7 9.1 0.87 10.1 9.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) U3_assoc_6 PF08640.11 EKX46188.1 - 0.032 14.3 4.5 1.2 9.3 0.3 2.4 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 PDZ_2 PF13180.6 EKX46190.1 - 5.4e-08 33.1 0.1 7.9e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX46190.1 - 4e-05 23.9 0.1 5.7e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX46190.1 - 0.0059 16.4 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Prenyltransf PF01255.19 EKX46191.1 - 3.4e-70 236.0 0.0 4.1e-70 235.8 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Peptidase_M48 PF01435.18 EKX46191.1 - 0.082 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M48 Filamin PF00630.19 EKX46192.1 - 2.4e-74 246.7 4.7 6.6e-21 75.1 0.1 5.0 5 0 0 5 5 5 4 Filamin/ABP280 repeat C2 PF00168.30 EKX46192.1 - 9.1e-21 74.1 0.1 3.3e-20 72.3 0.1 2.0 1 0 0 1 1 1 1 C2 domain Invasin_D3 PF09134.10 EKX46192.1 - 2.3e-09 37.4 0.1 0.037 14.3 0.1 4.8 4 0 0 4 4 4 2 Invasin, domain 3 Cadherin_5 PF17892.1 EKX46192.1 - 0.00093 19.1 1.1 1.4 8.9 0.0 3.8 4 0 0 4 4 4 2 Cadherin-like domain YtkA PF13115.6 EKX46192.1 - 0.0029 18.2 1.4 16 6.2 0.0 4.1 4 0 0 4 4 4 1 YtkA-like CE2_N PF17996.1 EKX46192.1 - 0.0048 16.9 0.3 2.2 8.3 0.0 3.5 3 0 0 3 3 3 1 Carbohydrate esterase 2 N-terminal FAD_binding_8 PF08022.12 EKX46192.1 - 0.065 13.3 0.0 0.93 9.6 0.0 2.3 2 0 0 2 2 2 0 FAD-binding domain EF-hand_7 PF13499.6 EKX46193.1 - 4.9e-06 26.9 4.4 9.7e-06 26.0 2.2 2.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX46193.1 - 0.00017 20.9 1.2 0.051 13.1 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EKX46193.1 - 0.0043 16.9 1.2 0.079 12.9 0.0 3.2 4 0 0 4 4 4 1 EF-hand domain EF-hand_9 PF14658.6 EKX46193.1 - 0.058 13.7 0.3 0.75 10.2 0.1 2.3 1 1 1 2 2 2 0 EF-hand domain EF-hand_8 PF13833.6 EKX46193.1 - 0.091 12.6 0.1 0.4 10.6 0.1 2.1 1 0 0 1 1 1 0 EF-hand domain pair zinc_ribbon_6 PF14599.6 EKX46194.1 - 0.038 14.0 1.8 9.1 6.4 0.0 4.3 4 0 0 4 4 4 0 Zinc-ribbon Daxx PF03344.15 EKX46194.1 - 0.089 12.9 3.0 0.17 12.0 0.9 2.6 2 0 0 2 2 2 0 Daxx N-terminal Rassf1C-interacting domain DUF4897 PF16238.5 EKX46194.1 - 0.28 11.0 15.1 0.033 14.0 1.2 3.8 4 1 0 4 4 4 0 Domain of unknown function (DUF4897) Methyltransf_21 PF05050.12 EKX46195.1 - 4.3e-15 56.2 0.0 6.9e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Surp PF01805.20 EKX46196.1 - 2e-17 62.9 0.0 3.8e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Surp module CTD_bind PF04818.13 EKX46196.1 - 0.0012 19.7 0.0 0.0027 18.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DNA_pol_B_thumb PF14791.6 EKX46196.1 - 0.13 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase beta thumb MFS_1_like PF12832.7 EKX46197.1 - 0.012 14.4 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 MFS_1 like family DUF2475 PF10629.9 EKX46198.1 - 0.0002 21.5 0.7 0.33 11.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2475) Urease_gamma PF00547.18 EKX46198.1 - 0.091 13.1 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Urease, gamma subunit Herpes_UL49_5 PF05702.11 EKX46200.1 - 0.0074 16.4 0.3 3.1 7.9 0.1 2.5 2 0 0 2 2 2 2 Herpesvirus UL49.5 envelope/tegument protein CBP_BcsQ PF06564.12 EKX46201.1 - 0.068 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ Ank_2 PF12796.7 EKX46202.1 - 2.2e-23 82.6 0.1 1.1e-12 48.3 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EKX46202.1 - 2e-19 69.1 0.8 2.9e-05 24.3 0.1 4.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EKX46202.1 - 1.6e-18 64.8 1.3 7.3e-05 22.9 0.2 4.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 EKX46202.1 - 4e-18 65.5 0.1 3.6e-08 33.8 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX46202.1 - 4.4e-17 61.9 3.3 5.5e-11 42.5 0.3 4.1 2 1 3 5 5 5 3 Ankyrin repeats (many copies) RWP-RK PF02042.15 EKX46203.1 - 9.7e-15 54.3 0.0 2e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX46203.1 - 0.13 12.0 0.1 0.95 9.3 0.0 2.2 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family Taq-exonuc PF09281.10 EKX46204.1 - 0.013 15.5 0.2 0.032 14.2 0.2 1.7 1 0 0 1 1 1 0 Taq polymerase, exonuclease Ndc1_Nup PF09531.10 EKX46204.1 - 0.05 12.3 7.1 0.064 11.9 7.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4551 PF15087.6 EKX46204.1 - 0.36 9.6 6.5 0.43 9.4 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) TRIQK PF15168.6 EKX46204.1 - 0.4 10.6 3.0 4 7.4 0.1 2.5 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family FYDLN_acid PF09538.10 EKX46204.1 - 2 9.1 9.4 1.7 9.3 3.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF3464 PF11947.8 EKX46204.1 - 2.7 7.7 6.6 1.1 9.0 0.3 2.3 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DUF4366 PF14283.6 EKX46204.1 - 5.4 7.1 9.9 0.77 9.8 0.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) Presenilin PF01080.17 EKX46204.1 - 6.3 5.5 7.9 10 4.8 7.9 1.3 1 0 0 1 1 1 0 Presenilin Alg6_Alg8 PF03155.15 EKX46205.1 - 1.6e-41 142.8 7.2 1.6e-37 129.7 1.3 2.9 2 1 1 3 3 3 2 ALG6, ALG8 glycosyltransferase family DUF2157 PF09925.9 EKX46205.1 - 0.12 12.2 1.2 0.38 10.6 1.2 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) Kinesin PF00225.23 EKX46206.1 - 2.9e-20 72.5 0.5 5.7e-20 71.5 0.5 1.4 1 0 0 1 1 1 1 Kinesin motor domain RCC1 PF00415.18 EKX46207.1 - 5.3e-34 116.6 17.0 7.6e-10 39.3 0.0 5.4 5 1 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX46207.1 - 1.8e-19 69.0 25.9 8.5e-05 22.2 1.4 4.2 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat UL73_N PF12522.8 EKX46207.1 - 0.0084 15.8 1.3 0.0084 15.8 1.3 1.7 2 0 0 2 2 2 1 Cytomegalovirus glycoprotein N terminal Myb_DNA-binding PF00249.31 EKX46209.1 - 8.4e-08 32.3 0.0 2.8e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 Myb-like DNA-binding domain TEA PF01285.18 EKX46209.1 - 0.058 13.5 0.0 0.17 12.0 0.0 1.8 1 1 0 1 1 1 0 TEA/ATTS domain Myb_DNA-binding PF00249.31 EKX46210.1 - 8.8e-08 32.2 0.0 2.9e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 Myb-like DNA-binding domain TEA PF01285.18 EKX46210.1 - 0.057 13.5 0.0 0.16 12.0 0.0 1.8 1 1 0 1 1 1 0 TEA/ATTS domain Myb_DNA-binding PF00249.31 EKX46211.1 - 2.1e-08 34.2 0.0 6.2e-08 32.7 0.0 1.8 1 1 0 1 1 1 1 Myb-like DNA-binding domain TEA PF01285.18 EKX46211.1 - 0.032 14.3 0.0 0.076 13.1 0.0 1.7 1 1 0 1 1 1 0 TEA/ATTS domain Gly_transf_sug PF04488.15 EKX46212.1 - 4.3e-08 33.7 0.0 9.8e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 EKX46212.1 - 0.018 14.3 0.1 0.032 13.5 0.1 1.3 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.12 EKX46212.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein UPF0054 PF02130.17 EKX46213.1 - 6.7e-08 32.4 0.0 1.2e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 BST2 PF16716.5 EKX46213.1 - 0.041 14.5 0.7 0.14 12.7 0.7 1.9 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 TSC22 PF01166.18 EKX46213.1 - 0.097 13.0 0.2 28 5.1 0.0 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF711 PF05167.12 EKX46214.1 - 2e-74 250.9 0.0 1e-70 238.7 0.0 2.0 1 1 1 2 2 2 2 Uncharacterised ACR (DUF711) Myb_DNA-binding PF00249.31 EKX46216.1 - 2.1e-07 31.0 0.1 1.3e-06 28.5 0.1 2.1 1 1 0 1 1 1 1 Myb-like DNA-binding domain SR-25 PF10500.9 EKX46216.1 - 0.013 15.1 2.1 0.017 14.7 2.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TEA PF01285.18 EKX46216.1 - 0.081 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 TEA/ATTS domain Myb_DNA-binding PF00249.31 EKX46217.1 - 3.1e-07 30.5 0.1 1.9e-06 28.0 0.1 2.1 1 1 0 1 1 1 1 Myb-like DNA-binding domain SR-25 PF10500.9 EKX46217.1 - 0.0083 15.8 1.6 0.011 15.4 1.6 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein TEA PF01285.18 EKX46217.1 - 0.093 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 TEA/ATTS domain Myb_DNA-binding PF00249.31 EKX46219.1 - 3.1e-07 30.5 0.1 1.9e-06 28.0 0.1 2.1 1 1 0 1 1 1 1 Myb-like DNA-binding domain SR-25 PF10500.9 EKX46219.1 - 0.012 15.2 1.3 0.016 14.8 1.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TEA PF01285.18 EKX46219.1 - 0.095 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 TEA/ATTS domain Glyco_trans_2_3 PF13632.6 EKX46220.1 - 3.3e-24 85.9 4.5 8.1e-24 84.6 4.5 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EKX46220.1 - 1.1e-09 38.6 0.0 1.4e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EKX46220.1 - 0.00022 20.7 0.1 0.0044 16.5 0.1 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 21 DUF5415 PF17436.2 EKX46220.1 - 0.086 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5415) AMP-binding PF00501.28 EKX46221.1 - 3.7e-81 272.9 0.0 1e-80 271.5 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 EKX46221.1 - 8.1e-10 39.6 0.1 1.6e-09 38.6 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF445 PF04286.12 EKX46222.1 - 1.2e-07 31.8 0.1 0.00016 21.6 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF445) Orf78 PF06024.12 EKX46222.1 - 0.04 14.2 1.4 0.04 14.2 1.4 4.1 3 1 0 3 3 3 0 Orf78 (ac78) Mit_KHE1 PF10173.9 EKX46222.1 - 0.12 12.4 1.0 0.58 10.2 0.6 2.2 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related ADH_zinc_N_2 PF13602.6 EKX46223.1 - 6.8e-13 49.8 0.0 7.7e-05 23.8 0.0 3.5 3 0 0 3 3 3 3 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EKX46223.1 - 1.3e-12 47.8 0.0 3.2e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EKX46223.1 - 6.2e-08 32.5 0.2 1.4e-06 28.2 0.0 3.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Keratin_2_head PF16208.5 EKX46223.1 - 0.017 15.3 10.8 0.017 15.3 10.8 2.6 3 0 0 3 3 3 0 Keratin type II head Voldacs PF03517.13 EKX46223.1 - 2 8.5 9.7 0.09 12.9 1.5 2.2 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling SPRY PF00622.28 EKX46224.1 - 0.09 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 SPRY domain PTPRCAP PF15713.5 EKX46224.1 - 7.5 6.8 23.2 7.2 6.9 7.8 3.6 3 1 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated GST_N PF02798.20 EKX46225.1 - 6.1e-13 48.9 0.0 9.7e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EKX46225.1 - 2.9e-08 34.0 0.0 4.3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EKX46225.1 - 5e-06 26.7 0.0 8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EKX46225.1 - 0.0021 18.2 0.0 0.0028 17.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EKX46225.1 - 0.0045 17.0 0.0 0.011 15.8 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EKX46225.1 - 0.0087 16.2 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pkr1 PF08636.10 EKX46227.1 - 1.6e-11 44.1 6.9 2.1e-11 43.8 6.9 1.1 1 0 0 1 1 1 1 ER protein Pkr1 DUF4131 PF13567.6 EKX46227.1 - 2.8 7.6 5.0 4.3 7.0 5.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2207 PF09972.9 EKX46227.1 - 2.9 6.6 4.4 3.8 6.2 4.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CTP_transf_1 PF01148.20 EKX46228.1 - 1.5e-69 234.7 15.8 2e-69 234.3 15.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family WD40 PF00400.32 EKX46229.1 - 9.1e-11 42.1 5.0 0.00021 22.0 0.4 4.2 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX46229.1 - 0.0013 18.9 0.2 5.2 7.4 0.0 4.2 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2946 PF11162.8 EKX46229.1 - 0.058 14.1 0.2 0.094 13.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) SpmSyn_N PF17950.1 EKX46229.1 - 0.11 12.7 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 S-adenosylmethionine decarboxylase N -terminal Phytochelatin PF05023.14 EKX46230.1 - 9.8e-30 103.4 0.0 1.3e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Phytochelatin synthase UvrA_DNA-bind PF17755.1 EKX46230.1 - 0.053 13.9 0.0 0.46 10.9 0.0 2.0 2 0 0 2 2 2 0 UvrA DNA-binding domain LcrG PF07216.12 EKX46230.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 LcrG protein Cation_ATPase PF13246.6 EKX46231.1 - 0.006 16.6 0.4 0.031 14.3 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EKX46231.1 - 0.2 11.9 0.0 1.9 8.7 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Pkinase_Tyr PF07714.17 EKX46232.1 - 1.1e-58 198.6 0.0 1.2e-58 198.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX46232.1 - 3.7e-51 174.0 0.0 4.7e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EKX46232.1 - 4.7e-08 32.2 0.0 6.6e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EKX46232.1 - 0.019 14.3 0.1 0.034 13.5 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX46232.1 - 0.03 14.3 0.1 0.053 13.4 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family YukC PF10140.9 EKX46232.1 - 0.044 12.6 0.0 0.06 12.2 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Haspin_kinase PF12330.8 EKX46232.1 - 0.15 11.0 0.0 0.31 9.9 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Stomagen PF16851.5 EKX46233.1 - 0.11 12.5 0.5 0.75 9.9 0.1 2.2 2 0 0 2 2 2 0 Stomagen Kelch_5 PF13854.6 EKX46234.1 - 9e-36 121.3 12.2 0.002 18.1 0.0 12.9 11 0 0 11 11 11 9 Kelch motif Kelch_4 PF13418.6 EKX46234.1 - 3.9e-24 84.4 32.4 0.00021 21.2 0.0 14.4 15 1 0 15 15 15 6 Galactose oxidase, central domain Filamin PF00630.19 EKX46234.1 - 1.2e-17 64.6 0.0 2.6e-09 37.8 0.0 3.7 3 0 0 3 3 3 2 Filamin/ABP280 repeat Kelch_3 PF13415.6 EKX46234.1 - 1.2e-14 54.1 34.9 0.18 12.1 0.0 13.8 13 0 0 13 13 13 5 Galactose oxidase, central domain Invasin_D3 PF09134.10 EKX46234.1 - 0.00024 21.3 0.0 0.045 14.1 0.0 3.2 3 0 0 3 3 3 1 Invasin, domain 3 Kelch_1 PF01344.25 EKX46234.1 - 0.0043 16.6 16.1 0.81 9.3 0.0 8.5 9 0 0 9 9 9 2 Kelch motif Kelch_6 PF13964.6 EKX46234.1 - 0.0043 17.3 23.7 7.8 6.9 0.1 10.7 12 0 0 12 12 12 2 Kelch motif RAG2 PF03089.14 EKX46234.1 - 0.018 14.1 0.0 1.8 7.5 0.0 3.8 4 0 0 4 4 4 0 Recombination activating protein 2 Kelch_2 PF07646.15 EKX46234.1 - 1.9 8.6 32.4 25 5.1 0.2 10.5 11 0 0 11 11 11 0 Kelch motif Bestrophin PF01062.21 EKX46235.1 - 1.5e-37 129.6 0.5 2.2e-37 129.1 0.5 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel RWP-RK PF02042.15 EKX46236.1 - 1.1e-14 54.1 0.0 1.7e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX46236.1 - 0.056 13.2 0.7 0.15 11.9 0.0 2.0 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family UPF0176_N PF17773.1 EKX46237.1 - 3.7e-24 84.9 0.0 1.1e-23 83.4 0.0 1.8 2 0 0 2 2 2 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 EKX46237.1 - 1.2e-10 41.9 0.0 2.7e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese_C PF12368.8 EKX46237.1 - 1.2e-08 35.2 16.1 2.5e-08 34.2 16.1 1.6 1 0 0 1 1 1 1 Rhodanase C-terminal Methyltransf_3 PF01596.17 EKX46238.1 - 4.4e-30 104.5 0.4 1.1e-28 99.9 0.4 2.0 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EKX46238.1 - 1.4e-06 29.2 0.0 1.1e-05 26.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EKX46238.1 - 0.015 15.0 0.0 0.023 14.3 0.0 1.3 1 1 0 1 1 1 0 Conserved hypothetical protein 95 Response_reg PF00072.24 EKX46238.1 - 0.068 13.3 0.2 1.5 9.0 0.0 2.2 2 0 0 2 2 2 0 Response regulator receiver domain TMEM65 PF10507.9 EKX46240.1 - 2.3e-37 127.3 5.5 2.5e-37 127.1 5.5 1.0 1 0 0 1 1 1 1 Transmembrane protein 65 zinc_ribbon_6 PF14599.6 EKX46241.1 - 4.4e-23 81.1 0.0 4.4e-23 81.1 0.0 3.3 3 0 0 3 3 3 1 Zinc-ribbon zf-CHY PF05495.12 EKX46241.1 - 3.8e-18 65.7 12.2 3.8e-18 65.7 12.2 3.6 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 EKX46241.1 - 4e-08 33.4 9.4 4e-08 33.4 9.4 5.5 3 2 2 5 5 5 1 Ring finger domain zf-RING_UBOX PF13445.6 EKX46241.1 - 9.4e-06 25.6 4.1 9.4e-06 25.6 4.1 4.7 4 3 1 5 5 5 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EKX46241.1 - 6.4e-05 22.7 8.2 6.4e-05 22.7 8.2 5.0 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX46241.1 - 8.4e-05 22.5 9.2 8.4e-05 22.5 9.2 5.9 4 1 1 5 5 5 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EKX46241.1 - 0.00041 20.1 10.1 0.00041 20.1 10.1 5.4 5 3 1 6 6 6 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EKX46241.1 - 0.0036 17.0 4.6 0.0036 17.0 4.6 4.6 4 0 0 4 4 4 1 RING-like zinc finger Na_Ca_ex PF01699.24 EKX46242.1 - 2.1e-46 157.6 32.0 1.4e-26 93.2 7.6 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein HAP PF03866.13 EKX46242.1 - 0.36 10.8 5.6 2.8 7.9 1.3 2.6 2 0 0 2 2 2 0 Hydrophobic abundant protein (HAP) Ank_5 PF13857.6 EKX46243.1 - 0.00027 21.2 0.0 1.1 9.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX46243.1 - 0.0074 16.8 0.0 0.11 13.1 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EKX46243.1 - 0.031 14.7 0.1 11 6.7 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeat Ank_3 PF13606.6 EKX46243.1 - 0.18 12.5 0.1 1.5 9.7 0.0 2.4 3 0 0 3 3 3 0 Ankyrin repeat DUF4051 PF13260.6 EKX46243.1 - 0.94 9.3 4.0 0.67 9.7 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) Pkinase PF00069.25 EKX46245.1 - 2.2e-47 161.7 0.0 2.6e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX46245.1 - 3e-31 108.6 0.0 7.3e-31 107.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX46245.1 - 3.2e-05 22.9 0.0 0.036 12.8 0.0 2.1 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 EKX46245.1 - 0.0046 16.9 0.0 0.02 14.8 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EKX46245.1 - 0.0075 15.2 0.0 0.11 11.4 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 EKX46245.1 - 0.022 14.1 0.0 0.042 13.2 0.0 1.4 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 EKX46245.1 - 0.032 13.6 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 EKX46245.1 - 0.093 11.7 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase FTA2 PF13095.6 EKX46245.1 - 0.2 11.3 0.0 0.42 10.2 0.0 1.6 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF4281 PF14108.6 EKX46246.1 - 1.5e-27 96.5 0.6 1.7e-27 96.3 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) MAPEG PF01124.18 EKX46246.1 - 0.075 12.9 0.3 0.091 12.7 0.3 1.3 1 1 0 1 1 1 0 MAPEG family TNFR_c6 PF00020.18 EKX46249.1 - 1.6e-12 47.6 89.9 2.4e-10 40.6 4.8 9.7 2 2 8 10 10 10 8 TNFR/NGFR cysteine-rich region Ephrin_rec_like PF07699.13 EKX46249.1 - 0.0014 18.4 94.0 0.058 13.2 6.7 7.8 1 1 8 9 9 9 7 Putative ephrin-receptor like NCD3G PF07562.14 EKX46249.1 - 2.2 8.3 75.5 0.17 11.9 9.5 6.5 1 1 6 7 7 7 0 Nine Cysteines Domain of family 3 GPCR FAM110_C PF14160.6 EKX46250.1 - 0.006 17.6 1.7 0.006 17.6 1.7 2.1 1 1 0 2 2 2 1 Centrosome-associated C terminus SID-1_RNA_chan PF13965.6 EKX46250.1 - 0.14 10.6 2.6 0.17 10.3 2.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Dynactin_p62 PF05502.13 EKX46250.1 - 0.23 10.2 9.7 0.28 9.9 9.7 1.0 1 0 0 1 1 1 0 Dynactin p62 family AAA_23 PF13476.6 EKX46250.1 - 1.3 9.5 8.5 1.7 9.1 8.5 1.2 1 0 0 1 1 1 0 AAA domain Tau95 PF09734.9 EKX46251.1 - 3.9e-32 112.0 1.8 5.3e-32 111.5 0.8 1.7 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 EKX46251.1 - 1.2e-16 61.1 0.0 1.4e-14 54.4 0.0 2.5 1 1 0 1 1 1 1 Tau95 Triple barrel domain Anoctamin PF04547.12 EKX46253.1 - 8.6e-73 245.7 15.1 1.1e-72 245.4 15.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 EKX46253.1 - 0.0017 18.1 0.5 0.0057 16.4 0.1 2.0 2 0 0 2 2 2 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin GTP_EFTU PF00009.27 EKX46254.1 - 8.9e-53 178.7 0.0 1.4e-52 178.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 EKX46254.1 - 3.2e-43 146.2 3.6 6.3e-43 145.3 3.6 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 EKX46254.1 - 7.7e-17 61.1 0.0 1.9e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EKX46254.1 - 6.5e-08 32.9 0.0 1.5e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EKX46254.1 - 1e-05 25.6 0.0 2.4e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 EKX46254.1 - 4.7e-05 23.2 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_II PF14492.6 EKX46254.1 - 0.0011 19.0 0.0 0.0048 17.0 0.0 2.1 1 1 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.22 EKX46254.1 - 0.0021 17.6 0.0 0.0045 16.6 0.0 1.4 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EKX46254.1 - 0.017 14.5 0.0 0.045 13.2 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.18 EKX46254.1 - 0.094 12.0 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Septin HSP70 PF00012.20 EKX46256.1 - 3.9e-262 870.8 4.4 4.5e-262 870.6 4.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EKX46256.1 - 1.8e-16 59.9 0.1 1e-15 57.4 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EKX46256.1 - 0.033 13.9 0.1 0.098 12.4 0.0 1.9 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain HSP70 PF00012.20 EKX46257.1 - 6.4e-262 870.1 4.4 7.2e-262 869.9 4.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EKX46257.1 - 8.3e-17 61.0 0.1 4.8e-16 58.5 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EKX46257.1 - 0.033 13.9 0.1 0.098 12.4 0.0 1.9 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain SHS2_FTSA PF02491.20 EKX46257.1 - 0.52 10.7 2.1 1.3 9.5 0.9 2.3 2 0 0 2 2 2 0 SHS2 domain inserted in FTSA MCM PF00493.23 EKX46259.1 - 3.3e-102 340.3 0.0 5.4e-102 339.6 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EKX46259.1 - 9.9e-33 112.7 0.3 2.3e-32 111.5 0.3 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EKX46259.1 - 8.2e-28 96.7 2.2 2.1e-27 95.4 2.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EKX46259.1 - 1.8e-18 67.0 0.1 3.9e-18 66.0 0.1 1.5 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EKX46259.1 - 1e-06 28.3 0.3 8.3e-05 22.1 0.0 2.8 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EKX46259.1 - 0.00018 21.4 0.0 0.00044 20.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_7 PF17867.1 EKX46259.1 - 0.0027 17.9 0.2 0.017 15.3 0.1 2.2 2 0 0 2 2 2 1 Midasin AAA lid domain AAA_5 PF07728.14 EKX46259.1 - 0.0031 17.5 0.0 0.01 15.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EKX46259.1 - 0.011 15.5 0.0 0.026 14.2 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase_C PF13335.6 EKX46259.1 - 0.053 14.2 3.3 0.079 13.6 0.8 2.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal Pkinase PF00069.25 EKX46260.1 - 2.2e-35 122.3 0.0 3.3e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 EKX46260.1 - 3.7e-23 82.1 0.3 3.8e-14 52.9 0.2 2.2 2 0 0 2 2 2 2 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 EKX46260.1 - 4.6e-20 72.0 0.0 6.9e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX46260.1 - 0.00038 20.5 0.0 0.0012 18.8 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX46260.1 - 0.00044 19.2 0.0 0.00062 18.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EKX46260.1 - 0.013 14.8 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Abhydrolase_1 PF00561.20 EKX46261.1 - 4e-06 26.7 0.4 0.0012 18.6 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EKX46261.1 - 0.00017 20.9 0.0 0.05 12.9 0.0 2.8 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Ndr PF03096.14 EKX46261.1 - 0.016 13.9 0.0 0.081 11.6 0.0 1.9 2 0 0 2 2 2 0 Ndr family DUF829 PF05705.14 EKX46261.1 - 0.022 14.6 0.4 0.19 11.6 0.4 2.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) Peptidase_S9 PF00326.21 EKX46261.1 - 0.059 12.8 0.5 1.3 8.5 0.5 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_8 PF06259.12 EKX46261.1 - 0.079 12.6 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_6 PF12697.7 EKX46261.1 - 0.084 13.5 0.6 0.28 11.8 0.6 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family FKBP_C PF00254.28 EKX46262.1 - 1.8e-31 108.3 0.0 2.1e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase C2 PF00168.30 EKX46264.1 - 1.1e-09 38.4 0.0 3.9e-09 36.7 0.0 1.9 1 1 0 1 1 1 1 C2 domain PDZ_2 PF13180.6 EKX46264.1 - 0.014 15.7 0.7 0.035 14.4 0.7 1.6 1 0 0 1 1 1 0 PDZ domain BORCS7 PF16088.5 EKX46264.1 - 0.015 15.5 0.1 0.015 15.5 0.1 2.1 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 7 IATP PF04568.12 EKX46264.1 - 0.091 13.2 0.2 0.21 12.0 0.2 1.6 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP TB2_DP1_HVA22 PF03134.19 EKX46265.1 - 1.8e-17 63.0 0.1 3.4e-17 62.1 0.1 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family C2 PF00168.30 EKX46265.1 - 0.0036 17.5 0.0 0.0063 16.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain DUF2304 PF10066.9 EKX46265.1 - 0.16 12.2 1.8 0.31 11.3 1.8 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) JAB PF01398.21 EKX46269.1 - 8e-32 109.7 0.4 1.4e-31 108.9 0.1 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 EKX46269.1 - 5.4e-24 84.9 1.6 9.5e-24 84.1 1.6 1.4 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 EKX46269.1 - 6.3e-05 22.7 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 EKX46269.1 - 0.0089 16.1 0.1 0.037 14.1 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) cNMP_binding PF00027.29 EKX46270.1 - 1.6e-25 89.0 0.1 6.2e-20 71.1 0.0 2.6 2 1 1 3 3 3 2 Cyclic nucleotide-binding domain Hydin_ADK PF17213.3 EKX46271.1 - 0.0023 18.2 0.0 0.0036 17.6 0.0 1.4 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain ADK PF00406.22 EKX46271.1 - 0.13 12.4 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Adenylate kinase ADK PF00406.22 EKX46272.1 - 6.7e-13 49.0 0.0 1.1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EKX46272.1 - 1e-08 35.7 0.0 1e-08 35.7 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 EKX46272.1 - 0.00037 20.8 0.0 0.0014 18.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EKX46272.1 - 0.00046 20.7 0.0 0.0016 19.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain FAP206 PF12018.8 EKX46272.1 - 0.0032 17.0 0.8 0.059 12.9 0.0 3.0 3 1 0 3 3 3 1 Domain of unknown function Hydin_ADK PF17213.3 EKX46272.1 - 0.15 12.3 4.2 1.1 9.5 0.0 3.0 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain TruD PF01142.18 EKX46272.1 - 4.5 6.0 6.6 0.27 10.0 1.1 1.6 2 0 0 2 2 2 0 tRNA pseudouridine synthase D (TruD) MscS_porin PF12795.7 EKX46273.1 - 1.2e-06 28.2 8.5 2.3e-06 27.4 8.5 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Hs1pro-1_C PF07014.12 EKX46273.1 - 0.0076 15.8 1.8 0.01 15.3 0.3 1.9 2 0 0 2 2 2 1 Hs1pro-1 protein C-terminus I_LWEQ PF01608.17 EKX46273.1 - 0.065 13.5 10.6 0.042 14.1 3.4 2.8 2 1 0 3 3 3 0 I/LWEQ domain Rota_NSP4 PF01452.16 EKX46273.1 - 0.079 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Rotavirus non structural protein DUF4745 PF15923.5 EKX46273.1 - 0.13 12.2 4.9 0.12 12.3 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4745) Retrotrans_gag PF03732.17 EKX46273.1 - 0.77 10.1 4.5 1 9.7 0.4 2.8 2 1 1 3 3 3 0 Retrotransposon gag protein DUF745 PF05335.13 EKX46273.1 - 1.3 8.8 14.1 0.49 10.1 6.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF745) CHAD PF05235.14 EKX46273.1 - 3.9 7.4 11.9 0.83 9.6 7.2 2.1 1 1 1 2 2 2 0 CHAD domain PDZ_6 PF17820.1 EKX46274.1 - 0.00015 21.6 0.0 0.00046 20.0 0.0 1.8 1 1 1 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX46274.1 - 0.00027 21.2 0.0 0.00036 20.8 0.0 1.2 1 0 0 1 1 1 1 PDZ domain ISN1 PF06437.11 EKX46275.1 - 6.9e-80 268.9 0.0 1.4e-71 241.6 0.0 2.0 1 1 1 2 2 2 2 IMP-specific 5'-nucleotidase Hydrolase_3 PF08282.12 EKX46275.1 - 0.028 14.2 0.0 7 6.3 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase zf-C3HC4_3 PF13920.6 EKX46276.1 - 1.5e-11 43.9 9.2 2.4e-11 43.3 9.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX46276.1 - 5.9e-08 32.9 7.1 1.1e-07 32.1 7.1 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EKX46276.1 - 3e-06 27.0 8.9 4.8e-06 26.3 8.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EKX46276.1 - 6.8e-06 25.9 5.3 1.3e-05 25.0 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EKX46276.1 - 3.2e-05 23.7 5.9 5.1e-05 23.0 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX46276.1 - 0.00055 19.8 5.0 0.0011 18.9 5.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-P11 PF03854.14 EKX46276.1 - 0.028 14.1 6.0 0.028 14.1 6.0 2.3 3 0 0 3 3 3 0 P-11 zinc finger zf-RING_4 PF14570.6 EKX46276.1 - 0.065 13.0 4.0 0.19 11.6 4.0 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain TB2_DP1_HVA22 PF03134.19 EKX46278.1 - 7.5e-21 73.9 2.2 1.5e-20 72.9 2.2 1.5 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Zn_clus PF00172.18 EKX46279.1 - 3.9e-09 36.5 7.3 6.2e-09 35.8 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SH3_3 PF08239.11 EKX46280.1 - 2e-06 28.0 0.4 5.8e-06 26.5 0.4 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain MCM PF00493.23 EKX46281.1 - 3.4e-97 324.0 0.1 5.3e-97 323.3 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EKX46281.1 - 8.4e-32 109.7 0.0 2.1e-31 108.4 0.0 1.7 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EKX46281.1 - 4.1e-23 81.6 0.0 1.1e-22 80.2 0.0 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EKX46281.1 - 1.1e-12 48.4 0.0 2.7e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EKX46281.1 - 2.8e-09 36.7 0.1 3.6e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EKX46281.1 - 0.00028 20.9 0.1 0.0013 18.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EKX46281.1 - 0.00045 20.1 0.1 0.0012 18.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EKX46281.1 - 0.00075 19.2 0.1 0.0017 18.1 0.1 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 EKX46281.1 - 0.11 12.9 0.0 0.31 11.5 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PARP PF00644.20 EKX46283.1 - 3.2e-06 26.9 0.7 7.9e-05 22.3 0.7 2.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain zf-FCS PF06467.14 EKX46283.1 - 0.039 13.9 11.8 0.058 13.3 2.5 3.3 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif CxC6 PF18721.1 EKX46283.1 - 3.2 8.1 14.6 0.25 11.6 1.0 3.2 1 1 1 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases Ribosomal_L12_N PF16320.5 EKX46286.1 - 0.14 11.9 3.0 0.4 10.4 3.0 1.8 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain K_channel_TID PF07941.11 EKX46286.1 - 3.2 8.3 13.2 1.9 9.0 2.8 2.5 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain bZIP_1 PF00170.21 EKX46287.1 - 7.3e-08 32.4 5.5 7.3e-08 32.4 5.5 3.6 3 1 1 4 4 4 1 bZIP transcription factor bZIP_2 PF07716.15 EKX46287.1 - 7.5e-07 29.1 4.0 7.5e-07 29.1 4.0 3.9 4 1 0 4 4 4 1 Basic region leucine zipper GIT_CC PF16559.5 EKX46287.1 - 0.0027 17.5 1.1 0.0027 17.5 1.1 2.7 3 0 0 3 3 3 1 GIT coiled-coil Rho guanine nucleotide exchange factor YabA PF06156.13 EKX46287.1 - 0.019 15.6 1.4 0.019 15.6 1.4 3.0 2 1 1 3 3 3 0 Initiation control protein YabA Cep57_CLD_2 PF14197.6 EKX46287.1 - 0.02 15.0 4.7 0.02 15.0 4.7 2.7 3 2 0 3 3 3 0 Centrosome localisation domain of PPC89 bZIP_Maf PF03131.17 EKX46287.1 - 0.087 13.4 28.2 0.047 14.2 10.8 3.2 2 1 1 3 3 3 0 bZIP Maf transcription factor DUF4407 PF14362.6 EKX46287.1 - 1.2 8.4 10.3 1.8 7.9 10.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MscS_TM PF12794.7 EKX46287.1 - 7.4 5.3 4.9 14 4.4 4.9 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 BatD PF13584.6 EKX46288.1 - 0.01 14.7 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance Orf78 PF06024.12 EKX46288.1 - 0.054 13.8 0.1 0.14 12.4 0.0 1.7 1 1 1 2 2 2 0 Orf78 (ac78) Saf_2TM PF18303.1 EKX46288.1 - 0.1 12.2 0.1 0.36 10.4 0.1 1.7 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain DUF4199 PF13858.6 EKX46289.1 - 0.0088 16.5 2.4 0.0097 16.3 1.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4199) DUF373 PF04123.13 EKX46289.1 - 0.048 13.1 1.2 0.096 12.1 1.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF373) CTV_P6 PF06706.11 EKX46289.1 - 0.24 11.1 3.7 0.43 10.3 0.4 2.2 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein Cadherin_3 PF16184.5 EKX46290.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Cadherin-like Pkinase PF00069.25 EKX46291.1 - 1.8e-58 198.0 0.0 2.2e-58 197.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX46291.1 - 8.8e-30 103.8 0.0 1e-29 103.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX46291.1 - 9.1e-06 25.2 0.0 1.9e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EKX46291.1 - 0.00052 18.9 0.2 0.001 17.9 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 EKX46291.1 - 0.0079 15.2 0.1 0.011 14.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EKX46291.1 - 0.047 13.0 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EKX46291.1 - 0.052 13.1 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family USP7_C2 PF14533.6 EKX46292.1 - 0.096 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal Pkinase PF00069.25 EKX46294.1 - 4.9e-18 65.4 0.0 6.9e-18 65.0 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX46294.1 - 0.029 13.7 0.8 0.062 12.6 0.0 1.9 3 0 0 3 3 3 0 Protein tyrosine kinase RWP-RK PF02042.15 EKX46296.1 - 1e-13 51.0 0.0 1.9e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain CobT PF06213.12 EKX46297.1 - 1.3 8.4 16.6 1.5 8.1 16.6 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Casc1_N PF15927.5 EKX46299.1 - 1e-17 64.5 20.5 1e-17 64.5 20.5 2.4 2 0 0 2 2 2 1 Cancer susceptibility candidate 1 N-terminus EF-hand_7 PF13499.6 EKX46300.1 - 2.6e-14 53.4 0.0 5.6e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX46300.1 - 4.8e-14 50.8 1.0 1.6e-05 24.1 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EKX46300.1 - 8.1e-12 44.1 1.1 7.8e-06 25.4 0.0 3.8 2 1 1 3 3 3 2 EF-hand domain Peptidase_C1 PF00112.23 EKX46300.1 - 7e-11 42.6 0.2 1e-07 32.3 0.0 2.3 2 0 0 2 2 2 2 Papain family cysteine protease EF-hand_5 PF13202.6 EKX46300.1 - 4e-10 38.7 0.5 0.00031 20.1 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EKX46300.1 - 5.4e-09 35.8 0.3 1.3e-06 28.1 0.1 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 EKX46300.1 - 0.0008 19.3 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EKX46300.1 - 0.093 13.1 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain Peptidase_C1_2 PF03051.15 EKX46300.1 - 0.16 10.7 0.1 0.23 10.2 0.1 1.1 1 0 0 1 1 1 0 Peptidase C1-like family Pkinase PF00069.25 EKX46301.1 - 2.3e-26 92.7 0.0 2.9e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX46301.1 - 4.9e-17 62.1 0.0 7.1e-17 61.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX46301.1 - 2e-08 33.5 1.0 2.7e-08 33.0 0.1 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EKX46301.1 - 9.9e-07 28.9 0.4 0.0021 18.0 0.0 2.8 4 0 0 4 4 4 2 Phosphotransferase enzyme family Atrophin-1 PF03154.15 EKX46301.1 - 0.0021 16.5 3.6 0.0028 16.0 3.6 1.1 1 0 0 1 1 1 1 Atrophin-1 family DUF3915 PF13054.6 EKX46301.1 - 0.11 12.4 3.1 0.23 11.4 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Ion_trans PF00520.31 EKX46302.1 - 7e-14 51.6 11.1 3.8e-08 32.9 1.5 2.4 2 0 0 2 2 2 2 Ion transport protein EF-hand_1 PF00036.32 EKX46302.1 - 0.0017 17.8 0.0 0.0062 16.0 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EKX46302.1 - 0.0023 17.7 0.5 0.11 12.5 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 EKX46302.1 - 0.091 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_7 PF13499.6 EKX46302.1 - 0.12 12.8 0.1 0.7 10.4 0.1 2.2 1 1 0 1 1 1 0 EF-hand domain pair Med3 PF11593.8 EKX46302.1 - 0.18 11.0 4.2 0.33 10.1 4.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Nup54 PF13874.6 EKX46303.1 - 1.3 9.1 7.9 2.6 8.2 7.9 1.7 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Abhydrolase_2 PF02230.16 EKX46304.1 - 1.5e-54 185.1 0.0 1.8e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 EKX46304.1 - 1.1e-09 38.2 0.0 2e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 EKX46304.1 - 1.6e-09 37.4 0.2 0.00079 18.8 0.0 3.1 2 1 1 3 3 3 2 Serine aminopeptidase, S33 FSH1 PF03959.13 EKX46304.1 - 1.9e-06 27.7 0.0 5.2e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) PGAP1 PF07819.13 EKX46304.1 - 4.4e-06 26.6 0.0 7.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 EKX46304.1 - 0.0001 22.2 0.1 0.0017 18.3 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EKX46304.1 - 0.00015 21.3 0.1 0.043 13.3 0.0 2.5 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EKX46304.1 - 0.00018 21.2 0.2 0.0031 17.2 0.2 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EKX46304.1 - 0.0012 19.4 0.0 0.003 18.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 EKX46304.1 - 0.0015 18.1 0.0 0.003 17.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Thioesterase PF00975.20 EKX46304.1 - 0.0022 18.2 0.1 0.016 15.3 0.0 2.1 1 1 1 2 2 2 1 Thioesterase domain Esterase PF00756.20 EKX46304.1 - 0.0061 16.2 0.0 0.021 14.5 0.0 1.8 2 0 0 2 2 2 1 Putative esterase Cutinase PF01083.22 EKX46304.1 - 0.011 15.7 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 Cutinase Abhydrolase_5 PF12695.7 EKX46304.1 - 0.025 14.4 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family AXE1 PF05448.12 EKX46304.1 - 0.093 11.4 0.2 0.16 10.6 0.2 1.6 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_4 PF08386.10 EKX46304.1 - 0.13 12.4 0.0 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 TAP-like protein PP2C PF00481.21 EKX46305.1 - 7.1e-41 140.5 0.0 8.2e-41 140.3 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EKX46305.1 - 1.3e-05 25.0 0.0 2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C UPF0242 PF06785.11 EKX46306.1 - 0.014 15.5 2.1 1.5 8.9 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Ribosomal_L36e PF01158.18 EKX46306.1 - 0.021 15.0 0.5 2.1 8.7 0.0 3.3 3 0 0 3 3 3 0 Ribosomal protein L36e AAA_2 PF07724.14 EKX46306.1 - 0.078 13.1 0.6 0.19 11.9 0.6 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Pox_A_type_inc PF04508.12 EKX46306.1 - 0.56 10.2 5.1 2.8 7.9 5.1 2.3 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF4387 PF14330.6 EKX46307.1 - 0.094 13.4 0.0 0.25 12.1 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4387) Ribosomal_S19 PF00203.21 EKX46309.1 - 3.2e-33 113.4 0.6 4.1e-33 113.1 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 WD40 PF00400.32 EKX46310.1 - 0.037 14.9 1.4 0.23 12.4 1.4 2.3 1 1 0 1 1 1 0 WD domain, G-beta repeat ubiquitin PF00240.23 EKX46311.1 - 1.3e-33 114.5 0.9 5.9e-18 64.4 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 EKX46311.1 - 1.6e-16 59.9 0.5 9.5e-10 38.2 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EKX46311.1 - 1.7e-10 41.4 0.2 0.00022 21.7 0.0 2.1 1 1 1 2 2 2 2 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EKX46311.1 - 3.1e-07 30.5 2.3 0.00012 22.1 0.1 2.7 1 1 1 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EKX46311.1 - 0.0001 22.2 0.1 0.068 13.1 0.0 2.2 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Blt1 PF12754.7 EKX46311.1 - 0.00022 21.6 1.7 0.16 12.3 0.2 2.1 1 1 1 2 2 2 2 Blt1 N-terminal domain Ubiquitin_4 PF18036.1 EKX46311.1 - 0.00073 19.5 3.4 0.44 10.6 0.1 2.7 2 2 1 3 3 3 2 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EKX46311.1 - 0.011 16.1 0.1 0.091 13.1 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-like domain Phage_sheath_1N PF17481.2 EKX46311.1 - 0.038 14.5 1.1 0.058 13.9 0.8 1.3 1 1 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain MCRS_N PF13325.6 EKX46311.1 - 0.046 13.7 0.0 0.054 13.5 0.0 1.2 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein Sec7 PF01369.20 EKX46312.1 - 9.9e-60 201.4 0.0 1.7e-59 200.6 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EKX46312.1 - 1.1e-13 51.3 0.2 1.1e-13 51.3 0.2 4.0 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal HpcH_HpaI PF03328.14 EKX46312.1 - 0.02 14.1 0.1 0.039 13.1 0.1 1.4 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family DUF4603 PF15376.6 EKX46312.1 - 0.057 10.8 0.1 0.093 10.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DUF3921 PF13060.6 EKX46312.1 - 0.18 11.8 0.1 0.59 10.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) Chorion_2 PF03964.15 EKX46312.1 - 2 9.3 8.7 0.29 12.0 0.8 2.5 2 0 0 2 2 2 0 Chorion family 2 Tim17 PF02466.19 EKX46313.1 - 2.9e-18 66.2 2.4 4.1e-18 65.8 2.4 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PI-TkoII_IV PF18714.1 EKX46313.1 - 0.041 13.4 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase II intein Domain IV DUF3671 PF12420.8 EKX46314.1 - 0.21 11.7 4.3 0.56 10.3 0.0 3.0 2 2 1 3 3 3 0 Protein of unknown function MHYT PF03707.16 EKX46314.1 - 0.71 10.1 4.4 2.3 8.4 0.1 3.5 4 0 0 4 4 4 0 Bacterial signalling protein N terminal repeat Pox_A14 PF05767.12 EKX46314.1 - 5.1 7.3 15.3 0.4 10.9 0.5 3.8 4 1 1 5 5 5 0 Poxvirus virion envelope protein A14 Pkinase PF00069.25 EKX46318.1 - 3.5e-18 65.9 0.0 4.3e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX46318.1 - 0.017 14.4 0.1 0.046 13.0 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase EF-hand_7 PF13499.6 EKX46319.1 - 0.0076 16.7 0.2 3.2 8.3 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair Band_3_cyto PF07565.13 EKX46319.1 - 0.096 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain TIR_2 PF13676.6 EKX46320.1 - 0.0032 18.1 0.0 0.02 15.5 0.0 2.3 2 1 1 3 3 3 1 TIR domain 7tm_6 PF02949.20 EKX46320.1 - 0.11 11.6 2.8 8.8 5.3 0.0 2.3 2 0 0 2 2 2 0 7tm Odorant receptor DUF3413 PF11893.8 EKX46320.1 - 3.4 6.7 6.3 5.7 6.0 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) WD40 PF00400.32 EKX46324.1 - 2e-17 63.2 5.6 5.8e-05 23.8 0.4 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX46324.1 - 0.00013 22.2 0.1 0.12 12.7 0.0 3.2 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1682 PF07946.14 EKX46324.1 - 0.87 8.7 7.4 1.4 8.1 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) N2227 PF07942.12 EKX46326.1 - 2e-87 292.8 0.0 2.8e-87 292.4 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_25 PF13649.6 EKX46326.1 - 0.0034 18.1 0.0 34 5.2 0.0 3.3 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_12 PF08242.12 EKX46326.1 - 0.03 15.1 0.0 0.51 11.1 0.0 2.6 1 1 0 1 1 1 0 Methyltransferase domain DUF5329 PF17263.2 EKX46326.1 - 0.076 13.2 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5329) Methyltransf_23 PF13489.6 EKX46326.1 - 0.088 12.6 0.0 0.21 11.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain FlhC PF05280.11 EKX46326.1 - 0.12 12.1 0.1 0.25 11.1 0.1 1.4 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) Mitochondr_Som1 PF11093.8 EKX46327.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial export protein Som1 DSPn PF14671.6 EKX46328.1 - 7e-29 101.1 0.0 1.6e-28 99.9 0.0 1.6 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EKX46328.1 - 4.3e-12 46.0 0.0 1.5e-11 44.2 0.0 1.9 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX46328.1 - 3e-05 23.7 0.0 4.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX46328.1 - 9.5e-05 22.6 0.0 0.00021 21.4 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EKX46328.1 - 0.0093 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family NB-ARC PF00931.22 EKX46328.1 - 0.062 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Pkinase PF00069.25 EKX46330.1 - 7.1e-17 61.6 0.0 1.5e-16 60.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX46330.1 - 0.056 12.7 0.8 0.098 11.9 0.0 1.8 3 0 0 3 3 3 0 Protein tyrosine kinase LrgB PF04172.16 EKX46332.1 - 1.3e-29 103.3 14.7 1.3e-29 103.3 14.7 2.3 2 0 0 2 2 2 1 LrgB-like family Phage_Coat_Gp8 PF05371.12 EKX46332.1 - 0.38 10.6 3.2 0.73 9.6 0.8 2.6 2 0 0 2 2 2 0 Phage major coat protein, Gp8 PAPS_reduct PF01507.19 EKX46333.1 - 0.002 18.2 0.8 0.002 18.2 0.8 1.6 1 1 1 2 2 2 1 Phosphoadenosine phosphosulfate reductase family MCPVI PF02993.14 EKX46333.1 - 0.034 14.0 0.7 0.037 13.9 0.7 1.1 1 0 0 1 1 1 0 Minor capsid protein VI DUF3510 PF12022.8 EKX46333.1 - 0.11 12.9 4.8 0.14 12.6 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) TrbI_Ftype PF09677.10 EKX46333.1 - 0.54 10.6 3.6 0.54 10.6 2.0 1.8 1 1 1 2 2 2 0 Type-F conjugative transfer system protein (TrbI_Ftype) RNase_J_C PF17770.1 EKX46333.1 - 0.55 11.3 3.2 0.72 11.0 0.2 2.0 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain PRTase_3 PF15610.6 EKX46334.1 - 6.3e-27 94.5 0.0 8.4e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 PRTase ComF-like RWP-RK PF02042.15 EKX46335.1 - 5.7e-15 55.0 0.0 1.1e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX46335.1 - 0.0039 16.9 0.7 0.61 9.9 0.0 3.1 1 1 2 3 3 3 1 Bacterial regulatory protein, Fis family RNA_pol_Rpb5_C PF01191.19 EKX46336.1 - 3e-32 110.3 0.2 5.5e-32 109.5 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 EKX46336.1 - 5.4e-13 49.3 0.3 1.2e-12 48.2 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Staphostatin_A PF09022.10 EKX46336.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Staphostatin A SF3A2 PF16835.5 EKX46336.1 - 0.062 13.7 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) cobW PF02492.19 EKX46337.1 - 2.6e-44 150.9 0.9 3.8e-44 150.4 0.9 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EKX46337.1 - 2.1e-19 69.2 0.1 4.2e-19 68.3 0.1 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_33 PF13671.6 EKX46337.1 - 0.0053 16.9 0.0 0.0092 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 EKX46337.1 - 0.017 15.2 0.4 0.069 13.1 0.1 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 EKX46337.1 - 0.024 14.6 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MobB PF03205.14 EKX46337.1 - 0.038 13.9 0.1 0.085 12.8 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.6 EKX46337.1 - 0.042 14.2 0.0 0.08 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain INT_SG_DDX_CT_C PF15300.6 EKX46337.1 - 0.045 13.5 0.0 0.096 12.5 0.0 1.5 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Viral_helicase1 PF01443.18 EKX46337.1 - 0.053 13.3 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EKX46337.1 - 0.1 12.8 0.1 0.32 11.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EKX46337.1 - 0.12 12.3 0.2 15 5.4 0.1 2.9 3 0 0 3 3 3 0 RsgA GTPase AAA_18 PF13238.6 EKX46337.1 - 0.13 12.8 0.0 0.32 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 EKX46337.1 - 0.15 11.0 0.5 7.7 5.4 0.1 2.6 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ResIII PF04851.15 EKX46338.1 - 1.9e-17 63.8 0.0 3.5e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EKX46338.1 - 3.7e-09 35.8 0.0 6.4e-09 35.0 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 EKX46338.1 - 1.2e-07 31.7 0.0 2.1e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX46338.1 - 0.0012 19.2 0.1 0.0052 17.1 0.0 2.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 EKX46338.1 - 0.016 14.9 0.0 0.037 13.7 0.0 1.6 2 0 0 2 2 2 0 SWI2/SNF2 ATPase Terminase_6 PF03237.15 EKX46338.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Terminase-like family DUF2870 PF11069.8 EKX46339.1 - 4.7e-40 135.9 2.6 4.7e-40 135.9 2.6 1.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2870) bZIP_1 PF00170.21 EKX46340.1 - 6.5e-10 39.0 33.5 1.8e-07 31.2 13.0 2.7 2 0 0 2 2 2 2 bZIP transcription factor bZIP_Maf PF03131.17 EKX46340.1 - 7.7e-07 29.6 21.4 3.9e-05 24.1 7.2 2.4 2 0 0 2 2 2 2 bZIP Maf transcription factor bZIP_2 PF07716.15 EKX46340.1 - 1.9e-06 27.9 7.2 1.9e-06 27.9 7.2 3.3 2 1 1 3 3 3 1 Basic region leucine zipper YabA PF06156.13 EKX46340.1 - 9.6e-05 23.0 3.1 0.0012 19.5 0.1 2.4 2 0 0 2 2 2 1 Initiation control protein YabA Cep57_CLD_2 PF14197.6 EKX46340.1 - 0.002 18.2 3.0 0.0048 17.0 3.0 1.6 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 Shugoshin_N PF07558.11 EKX46340.1 - 0.032 14.1 6.1 0.032 14.1 6.1 2.6 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region ZnuA PF01297.17 EKX46340.1 - 0.033 13.6 1.1 0.053 12.9 1.1 1.3 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic GIT_CC PF16559.5 EKX46340.1 - 0.64 9.9 4.5 1.8 8.5 4.5 1.8 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TylF PF05711.11 EKX46343.1 - 6.7e-09 35.4 0.0 8.7e-07 28.5 0.0 2.2 1 1 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.6 EKX46343.1 - 1.9e-05 25.7 0.0 5.6e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain DSPn PF14671.6 EKX46344.1 - 2.6e-31 108.9 0.3 5.1e-31 108.0 0.0 1.6 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EKX46344.1 - 7.5e-13 48.5 0.0 1.7e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX46344.1 - 4.4e-05 23.2 0.0 9e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX46344.1 - 0.00048 20.3 0.0 0.00098 19.3 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EKX46344.1 - 0.051 13.5 0.0 0.077 12.9 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Sel1 PF08238.12 EKX46345.1 - 5.2e-13 49.2 3.4 6.8e-07 29.8 0.0 3.8 3 1 1 4 4 4 3 Sel1 repeat Glyco_transf_17 PF04724.13 EKX46346.1 - 9e-38 130.2 0.0 1.2e-37 129.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 17 Big_3_5 PF16640.5 EKX46346.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) RETICULATA-like PF11891.8 EKX46347.1 - 2.3e-21 76.4 0.1 3.2e-21 76.0 0.1 1.1 1 0 0 1 1 1 1 Protein RETICULATA-related ChAPs PF09295.10 EKX46348.1 - 3.6e-51 174.4 0.0 9.2e-51 173.1 0.0 1.6 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 EKX46348.1 - 0.00045 20.7 5.3 0.0014 19.1 0.0 3.2 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX46348.1 - 0.00064 20.3 11.3 1.3 10.0 2.2 4.7 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX46348.1 - 0.0022 18.0 1.2 0.23 11.7 0.2 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX46348.1 - 0.021 14.6 0.2 7.4 6.6 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat 2-Hacid_dh_C PF02826.19 EKX46349.1 - 2.5e-36 124.7 0.0 3.7e-36 124.1 0.0 1.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 EKX46349.1 - 0.00015 21.9 0.7 0.00042 20.4 0.2 2.0 2 1 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 EKX46349.1 - 0.00028 21.1 0.0 0.00049 20.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EKX46349.1 - 0.0034 17.4 0.0 0.0063 16.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EKX46349.1 - 0.0078 16.8 0.0 0.015 15.9 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 EKX46349.1 - 0.015 14.9 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 EKX46349.1 - 0.025 15.1 0.0 0.055 14.0 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain NAD_binding_7 PF13241.6 EKX46349.1 - 0.05 14.0 0.0 0.09 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.18 EKX46349.1 - 0.093 13.0 0.0 0.28 11.4 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain PDZ_2 PF13180.6 EKX46350.1 - 4.8e-05 23.6 0.1 0.07 13.5 0.0 2.6 2 1 0 2 2 2 2 PDZ domain PDZ PF00595.24 EKX46350.1 - 0.00016 22.0 0.0 0.00043 20.6 0.0 1.8 1 1 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX46350.1 - 0.023 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Myosin_N PF02736.19 EKX46350.1 - 0.15 11.9 1.0 0.3 11.0 1.0 1.5 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain PDZ_2 PF13180.6 EKX46351.1 - 2.8e-05 24.3 0.0 4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX46351.1 - 0.00032 20.5 0.0 0.00049 19.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX46351.1 - 0.02 15.2 0.0 0.033 14.5 0.0 1.6 1 1 0 1 1 1 0 PDZ domain DnaJ PF00226.31 EKX46352.1 - 2.2e-24 85.4 0.2 6.2e-24 83.9 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain SNO PF01174.19 EKX46353.1 - 6.2e-48 163.1 0.0 7.2e-48 162.9 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 EKX46353.1 - 5.9e-09 35.8 0.0 8.4e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 EKX46353.1 - 5.2e-05 23.0 0.0 7.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 GATase PF00117.28 EKX46353.1 - 0.0018 18.1 0.4 0.011 15.5 0.4 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 EKX46353.1 - 0.069 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family Acetyltransf_1 PF00583.25 EKX46354.1 - 1.8e-13 50.8 0.1 2e-13 50.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EKX46354.1 - 3.2e-09 37.0 0.1 4.2e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EKX46354.1 - 1.5e-08 34.9 0.1 2.3e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EKX46354.1 - 2.6e-08 33.8 0.1 3.3e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EKX46354.1 - 0.00014 21.7 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EKX46354.1 - 0.00081 20.1 0.2 0.00099 19.8 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EKX46354.1 - 0.035 14.2 0.0 0.054 13.6 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Imm58 PF15581.6 EKX46354.1 - 0.12 12.4 0.1 0.23 11.6 0.1 1.5 1 1 0 1 1 1 0 Immunity protein 58 DUF1768 PF08719.11 EKX46355.1 - 3.3e-08 33.9 0.2 7.2e-08 32.8 0.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1768) Melibiase_2 PF16499.5 EKX46356.1 - 1.2e-63 214.9 1.4 2.9e-63 213.7 1.4 1.6 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EKX46356.1 - 2.1e-06 27.7 0.1 1.5e-05 25.0 0.0 2.3 2 1 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase_2_C PF17450.2 EKX46356.1 - 5.9e-05 23.2 0.0 0.00012 22.3 0.0 1.5 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase PF02065.18 EKX46356.1 - 0.0057 15.7 0.0 0.0099 14.9 0.0 1.3 1 0 0 1 1 1 1 Melibiase Iwr1 PF08574.10 EKX46358.1 - 6.4e-11 43.1 4.2 6.4e-11 43.1 4.2 2.6 2 0 0 2 2 2 1 Transcription factor Iwr1 Glyco_transf_10 PF00852.19 EKX46359.1 - 2.4e-19 69.7 0.0 2.9e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term CwfJ_C_1 PF04677.15 EKX46360.1 - 2.3e-14 53.3 0.1 4.4e-14 52.4 0.1 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 EKX46360.1 - 3e-13 50.5 0.0 3e-13 50.5 0.0 4.1 4 2 0 4 4 4 1 Protein similar to CwfJ C-terminus 2 zf-RanBP PF00641.18 EKX46360.1 - 6.6e-05 22.1 2.1 0.00014 21.1 2.1 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF755 PF05501.11 EKX46360.1 - 0.0024 18.2 31.4 0.0024 18.2 31.4 4.7 4 0 0 4 4 4 1 Domain of unknown function (DUF755) zf-ribbon_3 PF13248.6 EKX46360.1 - 0.75 9.3 2.2 1.5 8.3 2.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DUF3611 PF12263.8 EKX46361.1 - 4e-34 118.0 15.6 8.5e-34 117.0 15.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3611) LRR_6 PF13516.6 EKX46362.1 - 2.2e-15 55.3 6.2 0.00077 19.3 0.0 6.6 6 0 0 6 6 6 3 Leucine Rich repeat TPR_12 PF13424.6 EKX46362.1 - 2.5e-07 30.9 17.5 0.00036 20.8 0.1 5.6 7 0 0 7 7 7 2 Tetratricopeptide repeat LRR_4 PF12799.7 EKX46362.1 - 9.8e-07 29.0 3.8 0.019 15.4 0.2 4.2 2 1 3 5 5 5 3 Leucine Rich repeats (2 copies) TPR_9 PF13371.6 EKX46362.1 - 0.0005 20.2 5.5 0.22 11.7 0.0 3.7 2 1 2 4 4 4 2 Tetratricopeptide repeat LRR_8 PF13855.6 EKX46362.1 - 0.0047 16.7 1.3 0.85 9.4 0.0 3.6 3 0 0 3 3 3 1 Leucine rich repeat TPR_19 PF14559.6 EKX46362.1 - 0.0054 17.2 1.1 9 6.9 0.2 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat LRR_1 PF00560.33 EKX46362.1 - 0.0064 16.9 4.4 33 5.6 0.0 5.6 5 0 0 5 5 5 0 Leucine Rich Repeat TPR_16 PF13432.6 EKX46362.1 - 0.014 16.0 3.0 0.089 13.5 0.0 3.5 5 0 0 5 5 4 0 Tetratricopeptide repeat zf-FCS PF06467.14 EKX46362.1 - 0.027 14.4 2.9 0.077 13.0 2.9 1.8 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif TPR_8 PF13181.6 EKX46362.1 - 1.1 9.6 3.6 20 5.7 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX46362.1 - 1.8 8.6 7.5 1.8 8.5 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3552 PF12072.8 EKX46363.1 - 0.0024 17.3 11.2 0.077 12.4 11.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3552) Toxin_30 PF08117.11 EKX46363.1 - 0.046 14.0 21.0 5.7 7.3 2.6 3.9 1 1 2 3 3 3 0 Ptu family TPR_MLP1_2 PF07926.12 EKX46363.1 - 0.19 11.8 9.9 2.4 8.2 3.1 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Exonuc_VII_L PF02601.15 EKX46363.1 - 0.66 9.5 4.1 0.65 9.5 4.1 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit MSG PF02349.15 EKX46363.1 - 0.93 9.7 34.3 4.3 7.6 13.2 2.8 1 1 2 3 3 3 0 Major surface glycoprotein hNIFK_binding PF12196.8 EKX46363.1 - 1.2 8.7 71.5 7.8 6.1 0.6 11.4 1 1 6 7 7 7 0 FHA Ki67 binding domain of hNIFK ARA70 PF12489.8 EKX46363.1 - 4.1 7.6 6.8 19 5.4 6.8 1.9 1 1 0 1 1 1 0 Nuclear coactivator DUF3847 PF12958.7 EKX46363.1 - 4.8 7.4 29.7 1.8e+04 -16.6 29.7 4.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3847) FHA PF00498.26 EKX46366.1 - 1.3e-10 41.5 0.1 4.1e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EKX46366.1 - 1.3e-06 28.7 0.0 1e-05 25.7 0.0 2.6 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain SPRY PF00622.28 EKX46368.1 - 3.6e-05 23.9 0.3 0.0015 18.6 0.0 2.3 2 0 0 2 2 2 2 SPRY domain PDZ_6 PF17820.1 EKX46369.1 - 1.4e-06 28.0 0.3 3e-06 27.0 0.3 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX46369.1 - 3.9e-06 27.1 0.1 8.4e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PH PF00169.29 EKX46369.1 - 0.009 16.5 0.0 0.021 15.3 0.0 1.7 1 0 0 1 1 1 1 PH domain CrgA PF06781.12 EKX46369.1 - 0.099 12.7 1.3 0.36 10.9 0.6 2.2 2 0 0 2 2 2 0 Cell division protein CrgA PDZ PF00595.24 EKX46369.1 - 0.12 12.7 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 PDZ domain DUF2244 PF10003.9 EKX46369.1 - 0.27 10.9 1.4 0.52 10.0 1.4 1.5 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Myc_target_1 PF15179.6 EKX46369.1 - 0.37 10.7 1.8 1.3 8.9 0.0 2.6 3 0 0 3 3 3 0 Myc target protein 1 Vps16_C PF04840.12 EKX46370.1 - 0.18 10.8 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 Vps16, C-terminal region SRP54 PF00448.22 EKX46371.1 - 1.3e-69 233.8 1.0 1.7e-69 233.4 1.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 EKX46371.1 - 1.5e-07 31.5 0.1 6e-07 29.6 0.1 2.1 1 1 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.6 EKX46371.1 - 4.2e-05 23.4 1.9 7.6e-05 22.5 0.5 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EKX46371.1 - 4.6e-05 22.8 0.0 9.2e-05 21.8 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin CbiA PF01656.23 EKX46371.1 - 0.00011 22.3 0.5 0.00026 21.0 0.5 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.20 EKX46371.1 - 0.00058 19.8 0.2 0.002 18.0 0.1 1.9 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA PF00004.29 EKX46371.1 - 0.00081 19.8 0.7 0.0021 18.5 0.1 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 EKX46371.1 - 0.0018 18.7 0.2 0.0059 17.0 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_31 PF13614.6 EKX46371.1 - 0.0043 17.0 0.1 0.0085 16.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EKX46371.1 - 0.0073 16.6 0.4 0.02 15.2 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EKX46371.1 - 0.0086 16.2 0.1 0.026 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 EKX46371.1 - 0.017 14.3 0.4 0.048 12.8 0.2 1.8 2 0 0 2 2 2 0 Anion-transporting ATPase DUF2075 PF09848.9 EKX46371.1 - 0.018 14.3 0.1 0.029 13.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 EKX46371.1 - 0.043 13.7 1.7 0.092 12.7 0.8 2.0 2 1 1 3 3 2 0 NACHT domain Fer4_NifH PF00142.18 EKX46371.1 - 0.046 13.2 0.2 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_22 PF13401.6 EKX46371.1 - 0.072 13.4 0.2 0.75 10.1 0.0 2.5 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 EKX46371.1 - 0.072 13.5 0.2 0.22 11.9 0.1 1.9 1 1 1 2 2 2 0 AAA ATPase domain VirC1 PF07015.11 EKX46371.1 - 0.077 12.3 0.1 0.56 9.5 0.0 2.1 2 0 0 2 2 2 0 VirC1 protein ABC_tran PF00005.27 EKX46371.1 - 0.089 13.3 0.0 0.28 11.7 0.0 1.9 2 0 0 2 2 2 0 ABC transporter CRM1_repeat_2 PF18784.1 EKX46371.1 - 0.12 12.0 0.3 0.47 10.1 0.1 2.1 2 0 0 2 2 2 0 CRM1 / Exportin repeat 2 AAA_5 PF07728.14 EKX46371.1 - 0.18 11.8 0.5 0.58 10.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.17 EKX46371.1 - 1.3 8.7 4.1 0.47 10.1 0.7 2.0 2 1 1 3 3 3 0 Thymidylate kinase NTPase_1 PF03266.15 EKX46371.1 - 1.3 8.9 6.4 0.89 9.4 1.2 2.7 3 1 0 3 3 3 0 NTPase Phycoerythr_ab PF02972.14 EKX46372.1 - 3.2e-20 71.7 0.0 4.5e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Phycoerythrin, alpha/beta chain CK2S PF15011.6 EKX46373.1 - 0.06 13.2 0.0 0.069 13.0 0.0 1.1 1 0 0 1 1 1 0 Casein Kinase 2 substrate Ank_2 PF12796.7 EKX46375.1 - 1.5e-25 89.6 3.5 2e-11 44.3 0.6 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX46375.1 - 1.1e-22 79.7 2.2 1.9e-08 34.4 0.1 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX46375.1 - 1.5e-21 74.1 6.0 1.9e-05 24.7 0.0 6.7 6 1 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 EKX46375.1 - 1.8e-21 76.2 4.9 2.7e-05 24.6 0.1 4.5 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EKX46375.1 - 1.3e-19 69.7 7.2 2e-05 24.8 0.0 5.6 5 1 0 5 5 5 4 Ankyrin repeat DUF3517 PF12030.8 EKX46375.1 - 0.15 10.9 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3517) DUF327 PF03885.13 EKX46376.1 - 0.63 10.0 14.7 1 9.3 14.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF327) TBCC_N PF16752.5 EKX46376.1 - 0.7 10.4 14.2 0.23 11.9 9.1 2.2 1 1 1 2 2 2 0 Tubulin-specific chaperone C N-terminal domain DUF948 PF06103.11 EKX46376.1 - 0.84 9.9 5.4 0.99 9.7 2.1 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.6 EKX46376.1 - 0.85 8.9 8.3 1 8.7 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FixO PF02433.15 EKX46376.1 - 2.4 7.6 5.7 1.9 7.9 3.9 1.6 1 1 1 2 2 2 0 Cytochrome C oxidase, mono-heme subunit/FixO LMBR1 PF04791.16 EKX46376.1 - 7.8 5.3 6.2 8.5 5.1 6.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein LCAT PF02450.15 EKX46377.1 - 0.062 12.5 0.4 0.074 12.2 0.4 1.0 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Ank_2 PF12796.7 EKX46378.1 - 1.5e-18 67.1 6.6 9.3e-13 48.6 2.9 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX46378.1 - 2.7e-14 53.3 2.8 6e-08 33.1 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX46378.1 - 5.1e-13 49.0 4.3 6.5e-11 42.3 0.3 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX46378.1 - 1e-10 41.5 5.4 5.6e-05 23.4 0.0 3.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EKX46378.1 - 1.3e-09 37.4 2.9 0.00018 21.7 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat BtpA PF03437.15 EKX46379.1 - 2.9e-08 33.5 0.0 7.3e-08 32.2 0.0 1.7 2 0 0 2 2 2 1 BtpA family Alba PF01918.21 EKX46380.1 - 4.3e-17 61.7 0.2 6.5e-17 61.1 0.2 1.3 1 0 0 1 1 1 1 Alba CdvA PF18822.1 EKX46381.1 - 0.01 15.6 0.5 0.01 15.6 0.5 4.0 4 2 1 5 5 5 0 CdvA-like coiled-coil domain VASP_tetra PF08776.11 EKX46381.1 - 0.51 10.0 4.6 0.3 10.7 1.9 2.0 2 0 0 2 2 2 0 VASP tetramerisation domain Aida_N PF08910.10 EKX46381.1 - 1.6 9.2 8.2 0.085 13.3 0.6 2.7 3 1 0 3 3 3 0 Aida N-terminus SPX PF03105.19 EKX46381.1 - 3.8 7.3 7.5 0.29 11.0 2.3 1.8 2 0 0 2 2 2 0 SPX domain USP8_interact PF08941.10 EKX46382.1 - 0.0028 17.5 0.7 0.0084 15.9 0.5 1.8 1 1 1 2 2 2 1 USP8 interacting Ig_Tie2_1 PF10430.9 EKX46382.1 - 0.038 14.4 0.3 8.7 6.8 0.0 2.6 2 0 0 2 2 2 0 Tie-2 Ig-like domain 1 PKD_channel PF08016.12 EKX46384.1 - 2.6e-44 151.6 7.4 3.7e-44 151.1 7.4 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ras PF00071.22 EKX46386.1 - 7.1e-58 194.8 0.2 8.4e-58 194.5 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EKX46386.1 - 2.3e-32 111.7 0.0 3.6e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EKX46386.1 - 3.1e-13 49.6 0.1 3.5e-13 49.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EKX46386.1 - 1.2e-07 31.8 0.1 3.6e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EKX46386.1 - 1.2e-05 24.8 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EKX46386.1 - 2.2e-05 24.1 0.1 0.0015 18.1 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EKX46386.1 - 5.7e-05 23.1 0.3 0.0038 17.2 0.1 2.3 1 1 0 2 2 2 1 RsgA GTPase cobW PF02492.19 EKX46386.1 - 0.0004 20.0 0.1 0.0013 18.3 0.0 1.7 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 EKX46386.1 - 0.0036 17.1 0.1 0.097 12.4 0.1 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 EKX46386.1 - 0.0052 16.6 0.3 0.21 11.3 0.0 2.2 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Septin PF00735.18 EKX46386.1 - 0.0053 16.1 0.4 0.014 14.7 0.1 1.8 2 1 0 2 2 2 1 Septin AAA_22 PF13401.6 EKX46386.1 - 0.0086 16.4 0.0 0.021 15.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EKX46386.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EKX46386.1 - 0.01 15.5 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EKX46386.1 - 0.015 15.7 0.1 0.03 14.7 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 EKX46386.1 - 0.038 13.4 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.15 EKX46386.1 - 0.045 13.7 0.1 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 NTPase ATPase_2 PF01637.18 EKX46386.1 - 0.049 13.5 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TniB PF05621.11 EKX46386.1 - 0.064 12.7 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein G-alpha PF00503.20 EKX46386.1 - 0.076 12.2 0.1 0.29 10.3 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit NACHT PF05729.12 EKX46386.1 - 0.092 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 EKX46386.1 - 0.17 11.9 0.0 0.31 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TPR_12 PF13424.6 EKX46387.1 - 0.021 15.1 3.2 3.2 8.1 0.1 3.8 4 1 1 5 5 5 0 Tetratricopeptide repeat CBM_20 PF00686.19 EKX46389.1 - 2.9e-12 46.3 0.0 5.3e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Starch binding domain IKKbetaNEMObind PF12179.8 EKX46389.1 - 0.27 11.3 0.1 0.27 11.3 0.1 2.7 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain DUF2205 PF10224.9 EKX46389.1 - 2.3 8.3 12.4 0.14 12.2 1.3 3.3 3 1 0 3 3 3 0 Short coiled-coil protein TMF_DNA_bd PF12329.8 EKX46389.1 - 3.2 7.8 19.5 0.27 11.3 2.7 3.8 2 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Ion_trans PF00520.31 EKX46390.1 - 2e-22 79.6 12.9 3.1e-22 79.0 12.9 1.2 1 0 0 1 1 1 1 Ion transport protein EF-hand_6 PF13405.6 EKX46390.1 - 0.0021 17.9 0.0 0.0088 15.9 0.0 2.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 EKX46390.1 - 0.0035 16.8 0.1 0.012 15.1 0.1 2.0 1 0 0 1 1 1 1 EF hand PDZ_6 PF17820.1 EKX46391.1 - 4.3e-20 71.3 0.0 5.4e-09 35.8 0.0 2.5 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 EKX46391.1 - 5.2e-18 65.2 0.0 3.6e-09 36.8 0.0 2.5 1 1 1 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX46391.1 - 7.8e-15 55.0 0.0 3.5e-06 27.2 0.0 2.9 3 0 0 3 3 3 2 PDZ domain Tricorn_PDZ PF14685.6 EKX46391.1 - 8.6e-08 32.1 0.0 0.01 15.8 0.0 2.4 2 0 0 2 2 2 2 Tricorn protease PDZ domain Peptidase_S24 PF00717.23 EKX46391.1 - 0.065 13.2 0.0 3.9 7.5 0.0 3.1 3 1 0 3 3 3 0 Peptidase S24-like BIR PF00653.21 EKX46392.1 - 1.8e-19 70.2 0.1 2.6e-19 69.7 0.1 1.2 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain Myosin_tail_1 PF01576.19 EKX46392.1 - 0.0085 14.0 1.8 0.0099 13.7 1.8 1.0 1 0 0 1 1 1 1 Myosin tail APG6_N PF17675.1 EKX46392.1 - 0.012 16.1 0.1 0.015 15.8 0.1 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region zf-C3HC PF07967.13 EKX46392.1 - 0.027 14.5 0.1 0.073 13.1 0.0 1.7 2 0 0 2 2 2 0 C3HC zinc finger-like DNA_methylase PF00145.17 EKX46394.1 - 8.6e-34 117.4 0.0 1.3e-33 116.8 0.0 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase RRM_1 PF00076.22 EKX46396.1 - 2.5e-22 78.5 0.0 3e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EKX46396.1 - 0.019 14.8 0.0 0.027 14.3 0.0 1.3 1 1 0 1 1 1 0 Occluded RNA-recognition motif RRM_7 PF16367.5 EKX46396.1 - 0.099 12.8 0.0 0.19 11.8 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif Sel1 PF08238.12 EKX46397.1 - 3.4e-24 84.7 1.0 2.4e-08 34.4 0.0 4.1 4 0 0 4 4 4 4 Sel1 repeat TPR_6 PF13174.6 EKX46397.1 - 0.053 14.2 0.2 9.4 7.1 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat tRNA_edit PF04073.15 EKX46398.1 - 1.5e-18 67.0 0.3 2.6e-10 40.4 0.0 2.3 2 0 0 2 2 2 2 Aminoacyl-tRNA editing domain Pox_VP8_L4R PF04498.12 EKX46398.1 - 0.063 12.9 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Poxvirus nucleic acid binding protein VP8/L4R Glyco_transf_25 PF01755.17 EKX46399.1 - 1.7e-08 34.6 0.0 1e-06 28.8 0.0 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Exostosin PF03016.15 EKX46399.1 - 1.8e-06 27.4 0.0 3.3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Exostosin family 2-oxoacid_dh PF00198.23 EKX46402.1 - 5.7e-75 251.8 0.1 7.9e-75 251.3 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EKX46402.1 - 1.7e-22 79.0 0.2 3.5e-22 78.0 0.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EKX46402.1 - 1.3e-15 57.4 1.3 3.5e-15 56.1 0.3 2.3 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EKX46402.1 - 0.0011 18.7 0.3 0.92 9.4 0.1 2.5 2 0 0 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 EKX46402.1 - 0.13 13.0 0.3 1.7 9.4 0.0 2.7 2 1 1 3 3 3 0 HlyD family secretion protein Zn_clus PF00172.18 EKX46404.1 - 1.1e-13 51.0 25.9 5.4e-07 29.6 5.7 2.1 1 1 1 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI PF01437.25 EKX46404.1 - 2.4 8.8 15.9 1.8 9.2 1.6 3.3 2 2 1 3 3 3 0 Plexin repeat SUIM_assoc PF16619.5 EKX46406.1 - 0.0069 16.4 4.2 0.012 15.7 1.5 2.3 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 TPR_2 PF07719.17 EKX46406.1 - 0.019 15.1 0.0 1.5 9.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX46406.1 - 0.024 14.8 0.0 0.83 10.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX46406.1 - 0.95 10.2 3.4 2.7 8.8 0.0 3.4 5 0 0 5 5 5 0 Tetratricopeptide repeat ALIX_LYPXL_bnd PF13949.6 EKX46406.1 - 1.2 8.4 9.4 0.13 11.6 4.2 1.9 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV OmpH PF03938.14 EKX46406.1 - 5.4 7.4 10.2 0.93 9.8 4.5 2.3 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) KfrA_N PF11740.8 EKX46406.1 - 5.8 7.6 13.2 86 3.9 10.4 2.9 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term PH PF00169.29 EKX46407.1 - 1.9e-10 41.2 0.1 7.3e-10 39.3 0.1 2.1 1 0 0 1 1 1 1 PH domain IQ PF00612.27 EKX46407.1 - 0.028 14.2 1.2 0.065 13.1 1.2 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif PH_2 PF08458.10 EKX46407.1 - 0.1 12.9 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 Plant pleckstrin homology-like region Ank_4 PF13637.6 EKX46408.1 - 5.6e-13 49.1 0.3 6e-06 26.7 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX46408.1 - 8.4e-12 45.1 0.1 1e-11 44.8 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX46408.1 - 7.7e-11 42.4 0.2 3.1e-10 40.5 0.2 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX46408.1 - 2.3e-10 40.4 0.4 5.5e-06 26.6 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EKX46408.1 - 9.7e-09 34.8 0.5 0.00044 20.5 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Shigella_OspC PF06128.11 EKX46408.1 - 0.19 11.4 0.0 0.24 11.1 0.0 1.1 1 0 0 1 1 1 0 Shigella flexneri OspC protein GTP_cyclohydro2 PF00925.20 EKX46409.1 - 3.3e-50 169.9 0.0 4.2e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase II Pkinase PF00069.25 EKX46411.1 - 2.5e-36 125.4 0.0 3.2e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX46411.1 - 3.2e-30 105.3 0.0 4.5e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX46411.1 - 0.003 16.4 0.0 0.0041 15.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EKX46411.1 - 0.2 10.6 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 zf-RING_2 PF13639.6 EKX46412.1 - 9.4e-10 38.7 4.9 1.7e-09 37.8 4.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EKX46412.1 - 6.1e-08 32.8 4.2 1.4e-07 31.7 4.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EKX46412.1 - 8.6e-08 32.1 1.5 1.6e-07 31.2 1.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 EKX46412.1 - 2.6e-07 30.4 3.8 4.9e-07 29.5 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX46412.1 - 7.7e-07 29.0 1.7 0.0004 20.3 0.3 2.5 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4 PF00097.25 EKX46412.1 - 8.3e-07 28.8 4.3 1.8e-06 27.7 4.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX46412.1 - 3.5e-06 26.9 4.6 7e-06 25.9 4.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EKX46412.1 - 4.2e-06 26.5 4.0 7.5e-06 25.7 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX46412.1 - 2.8e-05 23.9 4.1 5.4e-05 23.0 4.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EKX46412.1 - 4.1e-05 23.1 5.1 7.2e-05 22.3 5.1 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 EKX46412.1 - 9e-05 22.1 7.3 0.00014 21.5 3.6 2.4 2 0 0 2 2 2 1 RING-like zinc finger TolA_bind_tri PF16331.5 EKX46412.1 - 0.0012 18.9 0.5 0.0012 18.9 0.5 3.2 2 1 0 3 3 3 1 TolA binding protein trimerisation zf-C3HC4_4 PF15227.6 EKX46412.1 - 0.0092 16.1 3.1 0.023 14.8 3.1 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF1192 PF06698.11 EKX46412.1 - 0.045 13.8 0.1 0.18 11.9 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DivIC PF04977.15 EKX46412.1 - 0.11 12.3 8.2 1.1 9.1 3.8 2.8 2 0 0 2 2 2 0 Septum formation initiator OTT_1508_deam PF14441.6 EKX46412.1 - 0.14 12.2 0.3 0.41 10.7 0.3 1.8 1 0 0 1 1 1 0 OTT_1508-like deaminase FANCL_C PF11793.8 EKX46412.1 - 0.15 12.3 5.2 0.62 10.3 5.2 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_6 PF14835.6 EKX46412.1 - 0.18 11.7 1.3 0.32 10.9 1.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING-like PF08746.11 EKX46412.1 - 0.27 11.6 4.5 0.7 10.2 4.5 1.7 1 0 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.5 EKX46412.1 - 0.33 11.0 3.7 1.3 9.1 3.7 2.0 1 1 0 1 1 1 0 Zinc-finger DUF5595 PF18077.1 EKX46412.1 - 0.38 10.8 3.4 0.87 9.7 0.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5595) RINGv PF12906.7 EKX46412.1 - 0.44 10.7 4.9 0.97 9.6 4.9 1.6 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 EKX46412.1 - 0.54 10.2 4.6 11 6.1 0.8 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 CHDCT2 PF08074.11 EKX46412.1 - 0.56 10.4 11.6 0.67 10.1 1.8 2.3 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain PG_binding_4 PF12229.8 EKX46412.1 - 0.82 10.0 3.7 1.1 9.6 0.2 2.9 3 1 0 3 3 3 0 Putative peptidoglycan binding domain PHD PF00628.29 EKX46412.1 - 1.1 9.3 4.1 2.9 7.9 4.1 1.8 1 1 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 EKX46412.1 - 1.9 8.4 3.9 2.8 7.8 3.0 1.8 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain DUF4404 PF14357.6 EKX46412.1 - 8.2 7.1 10.8 40 4.9 3.1 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) DUF1664 PF07889.12 EKX46412.1 - 10 6.2 10.3 11 6.1 3.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DZR PF12773.7 EKX46413.1 - 0.0033 17.4 0.1 0.0038 17.2 0.1 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 EKX46413.1 - 0.046 13.2 4.4 0.087 12.3 4.4 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 EKX46413.1 - 0.056 14.2 0.7 0.062 14.0 0.6 1.3 1 1 0 1 1 1 0 zinc-ribbon family zf-ACC PF17848.1 EKX46413.1 - 3.4 7.8 10.0 1.2 9.2 0.5 2.2 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain DUF3039 PF11238.8 EKX46414.1 - 0.19 11.5 0.1 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) ADK PF00406.22 EKX46415.1 - 4.4e-15 56.1 0.0 6.5e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EKX46415.1 - 2.9e-11 43.9 0.0 7.2e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EKX46415.1 - 9.9e-09 35.8 0.0 1.8e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EKX46415.1 - 9.6e-05 22.7 0.0 0.00022 21.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EKX46415.1 - 0.00011 22.4 0.0 0.00026 21.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EKX46415.1 - 0.0068 16.4 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Cytidylate_kin PF02224.18 EKX46415.1 - 0.022 14.5 0.0 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase NACHT PF05729.12 EKX46415.1 - 0.028 14.3 0.3 9.1 6.2 0.0 2.5 3 0 0 3 3 3 0 NACHT domain ABC_tran PF00005.27 EKX46415.1 - 0.054 14.0 0.1 0.38 11.3 0.0 2.2 2 1 0 2 2 2 0 ABC transporter AAA PF00004.29 EKX46415.1 - 0.055 13.9 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX46415.1 - 0.083 13.3 0.2 0.66 10.3 0.0 2.3 1 1 0 2 2 2 0 AAA ATPase domain dNK PF01712.19 EKX46415.1 - 0.15 11.9 0.0 0.47 10.3 0.0 1.8 2 0 0 2 2 2 0 Deoxynucleoside kinase TPR_MLP1_2 PF07926.12 EKX46416.1 - 1.2e-06 28.6 95.2 0.00068 19.7 28.0 5.6 2 2 2 5 5 5 3 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 EKX46416.1 - 3.8e-05 22.7 89.1 0.015 14.2 24.9 4.6 1 1 4 5 5 5 4 Spc7 kinetochore protein PDZ_2 PF13180.6 EKX46416.1 - 9.2e-05 22.7 0.1 0.00033 20.9 0.1 2.0 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX46416.1 - 0.00016 21.4 0.1 0.0022 17.8 0.0 2.4 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX46416.1 - 0.00023 21.4 0.2 0.00094 19.5 0.2 2.2 1 0 0 1 1 1 1 PDZ domain TMF_DNA_bd PF12329.8 EKX46416.1 - 0.0024 17.8 14.6 0.0024 17.8 14.6 9.7 2 1 8 10 10 10 4 TATA element modulatory factor 1 DNA binding FliJ PF02050.16 EKX46416.1 - 0.011 16.0 6.0 0.011 16.0 6.0 5.3 3 2 2 5 5 5 0 Flagellar FliJ protein ADIP PF11559.8 EKX46416.1 - 0.013 15.6 13.0 0.013 15.6 13.0 5.8 1 1 3 5 5 5 0 Afadin- and alpha -actinin-Binding ZapB PF06005.12 EKX46416.1 - 0.026 15.0 3.0 0.026 15.0 3.0 8.3 4 3 2 6 6 4 0 Cell division protein ZapB Calici_MSP PF05752.11 EKX46416.1 - 0.74 9.6 21.9 0.74 9.6 1.6 4.2 3 1 1 4 4 4 0 Calicivirus minor structural protein ApoO PF09769.9 EKX46416.1 - 0.88 9.5 24.0 0.61 10.0 0.9 5.0 2 1 2 5 5 5 0 Apolipoprotein O GAS PF13851.6 EKX46416.1 - 1.7 8.0 99.4 0.13 11.6 26.0 5.3 1 1 4 5 5 5 0 Growth-arrest specific micro-tubule binding DUF4201 PF13870.6 EKX46416.1 - 9.1 6.0 91.4 0.034 13.9 18.8 6.1 1 1 5 6 6 6 0 Domain of unknown function (DUF4201) DNA_ligase_A_M PF01068.21 EKX46417.1 - 2.7e-63 213.3 0.0 4.2e-63 212.7 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EKX46417.1 - 9e-44 149.8 0.7 1.6e-43 149.0 0.7 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EKX46417.1 - 7.2e-24 84.3 0.0 1.6e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EKX46417.1 - 6.1e-07 29.9 0.0 1e-06 29.2 0.0 1.4 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 EKX46417.1 - 0.03 14.3 0.2 1 9.4 0.0 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain DUF2358 PF10184.9 EKX46418.1 - 4e-10 40.0 0.0 7.3e-10 39.1 0.0 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) MMU163 PF17119.5 EKX46418.1 - 0.061 12.5 0.0 0.21 10.7 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis Acetyltransf_1 PF00583.25 EKX46420.1 - 0.0067 16.6 0.0 0.009 16.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Y_phosphatase2 PF03162.13 EKX46421.1 - 2e-48 164.1 0.0 2.2e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family ERO1 PF04137.15 EKX46422.1 - 1.7e-99 333.4 0.0 4.4e-99 332.0 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) FAD_binding_2 PF00890.24 EKX46422.1 - 9.7e-79 265.4 2.5 1.3e-78 265.0 2.5 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 EKX46422.1 - 2.2e-20 72.6 0.0 4.9e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 EKX46422.1 - 7.1e-09 35.7 1.2 1.1e-07 31.7 0.6 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EKX46422.1 - 2.3e-07 31.0 4.2 3.6e-07 30.3 1.5 2.8 4 0 0 4 4 3 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EKX46422.1 - 2.5e-07 30.4 1.7 4.7e-07 29.5 1.7 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EKX46422.1 - 1.5e-05 24.4 4.3 2.6e-05 23.6 1.6 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EKX46422.1 - 8.9e-05 21.9 0.1 0.00014 21.3 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EKX46422.1 - 0.00049 18.9 0.6 0.00049 18.9 0.6 2.6 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.6 EKX46422.1 - 0.00061 19.1 2.4 0.077 12.2 0.8 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EKX46422.1 - 0.00071 18.9 1.7 0.0018 17.6 1.7 1.7 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EKX46422.1 - 0.0067 15.5 3.6 0.0076 15.4 1.2 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 EKX46422.1 - 0.0088 15.3 6.1 0.07 12.4 1.7 2.3 2 0 0 2 2 2 1 Thi4 family GMC_oxred_N PF00732.19 EKX46422.1 - 0.031 13.7 0.1 0.34 10.2 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase Pyr_redox PF00070.27 EKX46422.1 - 0.032 14.8 0.4 0.094 13.3 0.4 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EKX46422.1 - 0.059 12.4 0.7 0.11 11.5 0.7 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EKX46422.1 - 0.12 11.7 1.2 0.23 10.7 1.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PHC2_SAM_assoc PF16616.5 EKX46423.1 - 0.023 15.5 3.6 0.026 15.3 3.6 1.2 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Zn_clus PF00172.18 EKX46424.1 - 7.4e-12 45.2 31.5 1.1e-05 25.4 12.6 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Aa_trans PF01490.18 EKX46425.1 - 4.2e-40 137.7 12.8 4.2e-40 137.7 12.8 1.9 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein HEPN_SAV2148 PF18725.1 EKX46426.1 - 0.08 12.3 4.5 1.5 8.2 1.0 2.6 2 0 0 2 2 2 0 SAV2148-like HEPN Baculo_PEP_C PF04513.12 EKX46426.1 - 0.22 11.6 23.1 0.37 10.8 0.1 4.8 3 2 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2721 PF11026.8 EKX46426.1 - 1.5 8.7 5.7 1.3 8.9 1.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) Ribosomal_L9_C PF03948.14 EKX46428.1 - 8.9e-15 54.9 1.3 8.9e-15 54.9 1.3 2.0 2 0 0 2 2 2 1 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.19 EKX46428.1 - 2.9e-13 49.2 2.7 7.2e-13 47.9 0.3 2.6 3 0 0 3 3 3 1 Ribosomal protein L9, N-terminal domain PIH1 PF08190.12 EKX46428.1 - 0.039 13.4 0.1 0.05 13.1 0.1 1.2 1 0 0 1 1 1 0 PIH1 N-terminal domain PDZ_3 PF17815.1 EKX46429.1 - 0.014 15.3 3.8 0.94 9.3 0.1 2.9 2 1 0 2 2 2 0 PDZ domain RHSP PF07999.11 EKX46430.1 - 0.0015 17.4 0.2 0.0085 15.0 0.2 1.9 1 1 0 1 1 1 1 Retrotransposon hot spot protein FAM76 PF16046.5 EKX46430.1 - 0.0084 15.5 1.8 0.013 14.8 1.8 1.2 1 0 0 1 1 1 1 FAM76 protein AAA_16 PF13191.6 EKX46430.1 - 0.018 15.4 0.0 0.066 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain DUF3584 PF12128.8 EKX46430.1 - 0.024 12.2 4.2 0.034 11.7 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IstB_IS21 PF01695.17 EKX46430.1 - 0.13 12.0 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein D5_N PF08706.11 EKX46430.1 - 0.16 12.3 4.2 0.082 13.2 0.4 2.2 2 0 0 2 2 2 0 D5 N terminal like AAA_13 PF13166.6 EKX46430.1 - 0.2 10.3 4.3 0.27 9.8 4.3 1.1 1 0 0 1 1 1 0 AAA domain zf-C4H2 PF10146.9 EKX46431.1 - 0.013 15.8 0.9 0.019 15.3 0.9 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein RSN1_7TM PF02714.15 EKX46432.1 - 6.1e-06 25.7 8.3 6.1e-06 25.7 8.3 2.2 1 1 1 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PaaX_C PF08223.11 EKX46432.1 - 0.085 13.1 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain AAR2 PF05282.11 EKX46433.1 - 1.6e-52 179.1 1.0 2e-51 175.4 1.0 2.0 1 1 0 1 1 1 1 AAR2 protein Ribosomal_L44 PF00935.19 EKX46434.1 - 1.4e-32 112.0 12.1 2.4e-32 111.2 12.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L44 FSH1 PF03959.13 EKX46435.1 - 3.4e-41 141.3 0.0 7.2e-40 136.9 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Thioesterase PF00975.20 EKX46435.1 - 2.7e-05 24.4 0.2 4.6e-05 23.6 0.1 1.4 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_2 PF02230.16 EKX46435.1 - 0.00055 19.8 0.1 0.001 18.9 0.1 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EKX46435.1 - 0.0081 16.8 0.6 1.5 9.4 0.0 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.18 EKX46435.1 - 0.011 15.4 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family ATPgrasp_N PF18130.1 EKX46435.1 - 0.057 14.0 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp N-terminal domain BAAT_C PF08840.11 EKX46435.1 - 0.22 11.4 0.1 12 5.7 0.0 2.2 1 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal EamA PF00892.20 EKX46436.1 - 9.7e-08 32.3 24.9 6.5e-07 29.6 8.4 3.0 2 2 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EKX46436.1 - 2e-05 24.1 12.3 2.5e-05 23.8 12.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family RabGAP-TBC PF00566.18 EKX46437.1 - 3.8e-12 46.3 1.0 6.6e-12 45.5 1.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ANTH PF07651.16 EKX46437.1 - 0.097 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 ANTH domain YqfQ PF14181.6 EKX46438.1 - 1 9.5 8.0 0.5 10.5 0.8 2.2 2 0 0 2 2 2 0 YqfQ-like protein EGF_2 PF07974.13 EKX46439.1 - 7.2e-05 23.1 9.2 0.00017 21.9 9.2 1.7 1 0 0 1 1 1 1 EGF-like domain O-FucT PF10250.9 EKX46439.1 - 0.0011 18.7 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase EGF_Tenascin PF18720.1 EKX46439.1 - 0.0042 17.1 2.0 0.014 15.5 2.0 1.9 1 0 0 1 1 1 1 Tenascin EGF domain PIP5K PF01504.18 EKX46439.1 - 0.065 12.5 0.2 0.1 11.8 0.2 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase RR_TM4-6 PF06459.12 EKX46439.1 - 2 8.2 17.1 2.9 7.6 17.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Paf1 PF03985.13 EKX46439.1 - 2.6 7.0 23.5 4.1 6.3 23.5 1.2 1 0 0 1 1 1 0 Paf1 Band_3_cyto PF07565.13 EKX46439.1 - 3.8 7.2 7.0 6.5 6.5 7.0 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Neur_chan_memb PF02932.16 EKX46439.1 - 6.2 6.8 5.3 10 6.1 5.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Roughex PF06020.11 EKX46439.1 - 6.4 5.8 17.6 7.7 5.5 16.4 1.6 2 0 0 2 2 2 0 Drosophila roughex protein DUF2828 PF11443.8 EKX46439.1 - 6.6 4.7 7.8 8.9 4.3 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF913 PF06025.12 EKX46439.1 - 9.3 5.1 6.2 14 4.5 6.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) ANAPC15 PF15243.6 EKX46440.1 - 0.014 15.8 3.2 0.02 15.3 3.2 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 CENP-B_dimeris PF09026.10 EKX46440.1 - 0.26 11.7 9.3 0.48 10.8 9.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4611 PF15387.6 EKX46440.1 - 0.45 10.8 5.3 0.77 10.0 5.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 EKX46440.1 - 0.88 7.6 3.8 1.1 7.3 3.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 EKX46440.1 - 3.5 6.9 6.4 4.7 6.4 6.4 1.1 1 0 0 1 1 1 0 NOA36 protein zf-CSL PF05207.13 EKX46442.1 - 5e-08 32.5 0.8 7.5e-08 32.0 0.8 1.3 1 0 0 1 1 1 1 CSL zinc finger Sec63 PF02889.16 EKX46443.1 - 7.4e-124 412.0 0.5 3.3e-78 262.4 0.2 3.4 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.29 EKX46443.1 - 3e-52 176.9 0.5 3e-27 95.5 0.5 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 EKX46443.1 - 1.2e-26 93.8 0.0 4.3e-14 52.9 0.0 2.8 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EKX46443.1 - 1.3e-14 54.5 0.2 4e-06 27.1 0.0 3.9 3 1 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EKX46443.1 - 1.6e-09 38.2 0.4 0.00011 22.5 0.1 3.5 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EKX46443.1 - 2.4e-06 28.0 1.2 0.0018 18.6 0.5 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EKX46443.1 - 0.0072 15.9 2.4 2.6 7.6 0.2 3.0 3 0 0 3 3 3 2 AAA domain T2SSE PF00437.20 EKX46443.1 - 0.015 14.4 0.0 2.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 EKX46443.1 - 0.04 13.6 0.2 18 5.0 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein TniB PF05621.11 EKX46443.1 - 0.046 13.1 1.0 8.4 5.8 0.0 3.6 3 0 0 3 3 3 0 Bacterial TniB protein Mon1 PF03164.14 EKX46443.1 - 0.048 12.7 0.8 1.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Trafficking protein Mon1 PhoH PF02562.16 EKX46443.1 - 0.076 12.5 0.0 5 6.5 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein SOBP PF15279.6 EKX46443.1 - 0.12 12.9 0.1 0.25 11.9 0.1 1.5 1 0 0 1 1 1 0 Sine oculis-binding protein Glyco_transf_41 PF13844.6 EKX46446.1 - 2.3e-62 211.0 0.1 5.3e-35 120.8 0.1 3.0 2 1 1 3 3 3 3 Glycosyl transferase family 41 TPR_1 PF00515.28 EKX46446.1 - 5.6e-10 38.6 0.0 0.0013 18.4 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX46446.1 - 3.1e-09 36.2 0.0 0.0027 17.7 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX46446.1 - 3.7e-09 36.7 0.1 1.2e-08 35.1 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX46446.1 - 3.2e-08 33.2 0.0 0.004 17.3 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX46446.1 - 4.3e-07 30.2 0.7 0.01 16.6 0.4 3.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX46446.1 - 1e-06 28.3 0.3 0.002 18.0 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX46446.1 - 1.8e-05 24.8 0.0 5.5e-05 23.3 0.0 1.9 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX46446.1 - 7.4e-05 22.3 0.0 0.41 10.4 0.1 2.5 1 1 1 2 2 2 2 TPR repeat TPR_10 PF13374.6 EKX46446.1 - 8.1e-05 22.4 2.0 0.0052 16.6 0.7 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX46446.1 - 0.00023 21.7 0.2 0.00096 19.8 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX46446.1 - 0.011 16.3 0.1 0.22 12.1 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 EKX46446.1 - 0.011 15.9 0.2 0.036 14.2 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX46446.1 - 0.022 14.8 0.1 0.088 12.9 0.0 1.9 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Tup_N PF08581.10 EKX46448.1 - 0.0029 17.9 5.3 0.0029 17.9 5.3 6.4 4 2 3 7 7 7 1 Tup N-terminal DUF533 PF04391.12 EKX46448.1 - 0.0037 16.9 40.4 0.042 13.4 10.1 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF533) TPR_MLP1_2 PF07926.12 EKX46448.1 - 0.0059 16.7 18.7 0.0059 16.7 18.7 6.1 2 2 3 6 6 6 1 TPR/MLP1/MLP2-like protein Peptidase_S10 PF00450.22 EKX46448.1 - 8.4 5.7 19.4 5.8 6.2 12.8 2.2 1 1 1 2 2 2 0 Serine carboxypeptidase Kelch_1 PF01344.25 EKX46449.1 - 1.5e-73 242.2 19.8 2e-16 59.3 0.2 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 EKX46449.1 - 3.6e-33 112.8 0.3 1.2e-06 28.6 0.0 6.4 4 1 2 6 6 6 6 Kelch motif Kelch_2 PF07646.15 EKX46449.1 - 5e-30 102.3 6.9 6.9e-07 29.0 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 EKX46449.1 - 6e-26 90.2 0.1 1.2e-05 25.2 0.0 5.5 4 1 1 5 5 5 5 Galactose oxidase, central domain BTB PF00651.31 EKX46449.1 - 6.6e-26 90.7 0.0 2e-25 89.2 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Kelch_3 PF13415.6 EKX46449.1 - 3.9e-17 62.1 5.4 6.7e-06 26.3 0.0 6.2 6 0 0 6 6 6 3 Galactose oxidase, central domain BACK PF07707.15 EKX46449.1 - 3e-09 36.9 3.7 1.2e-08 35.0 3.7 2.1 1 1 0 1 1 1 1 BTB And C-terminal Kelch Kelch_5 PF13854.6 EKX46449.1 - 6.5e-06 26.0 2.9 3.2 7.9 0.0 4.7 4 0 0 4 4 4 2 Kelch motif SnoaL_2 PF12680.7 EKX46449.1 - 0.028 15.0 0.0 0.073 13.7 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain HTH_Tnp_Tc3_2 PF01498.18 EKX46450.1 - 0.029 14.6 0.1 0.053 13.8 0.1 1.4 1 0 0 1 1 1 0 Transposase Pkinase PF00069.25 EKX46451.1 - 8.4e-56 189.2 0.1 9.3e-56 189.1 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX46451.1 - 6.9e-37 127.1 0.0 7.7e-37 127.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX46451.1 - 0.00023 21.2 0.1 0.1 12.5 0.1 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EKX46451.1 - 0.00041 19.7 0.0 0.51 9.6 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 EKX46451.1 - 0.005 16.2 0.3 0.01 15.2 0.3 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EKX46451.1 - 0.056 12.4 0.2 0.07 12.1 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 EKX46451.1 - 0.077 12.6 0.1 0.11 12.1 0.1 1.4 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 EKX46451.1 - 0.093 12.3 0.3 0.18 11.4 0.3 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase TMF_DNA_bd PF12329.8 EKX46452.1 - 7.7e-05 22.6 11.4 7.7e-05 22.6 11.4 6.2 2 2 5 7 7 7 1 TATA element modulatory factor 1 DNA binding HMMR_N PF15905.5 EKX46452.1 - 0.0056 16.2 19.1 0.0056 16.2 19.1 4.2 1 1 2 3 3 3 2 Hyaluronan mediated motility receptor N-terminal APG6_N PF17675.1 EKX46452.1 - 0.02 15.4 10.7 0.02 15.4 10.7 4.7 1 1 1 3 3 3 0 Apg6 coiled-coil region Cast PF10174.9 EKX46452.1 - 3.4 5.8 70.3 3.5 5.7 36.0 2.6 1 1 1 2 2 2 0 RIM-binding protein of the cytomatrix active zone LRR_8 PF13855.6 EKX46453.1 - 8e-32 108.8 23.7 3.4e-10 39.5 3.0 4.3 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EKX46453.1 - 4.6e-22 77.7 32.0 1.4e-06 28.5 0.8 5.8 3 1 3 7 7 7 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX46453.1 - 3.3e-07 30.3 5.8 0.0083 16.1 0.3 2.7 2 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EKX46453.1 - 1.5e-06 27.9 34.1 1.3 9.8 0.6 9.0 8 2 0 8 8 8 5 Leucine Rich Repeat LRR_6 PF13516.6 EKX46453.1 - 0.013 15.5 26.4 0.9 9.8 0.2 7.2 7 0 0 7 7 7 0 Leucine Rich repeat PDZ PF00595.24 EKX46454.1 - 7.8e-08 32.6 0.1 1.8e-07 31.4 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX46454.1 - 2.7e-05 23.9 0.0 5.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX46454.1 - 0.082 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 PDZ domain LRR_6 PF13516.6 EKX46455.1 - 1.8e-10 40.0 1.8 0.038 14.0 0.1 3.6 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.7 EKX46455.1 - 0.012 16.1 0.1 17 6.0 0.1 3.1 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX46455.1 - 0.015 15.7 1.4 30 5.7 0.0 3.8 3 1 0 3 3 3 0 Leucine Rich Repeat MFS_2 PF13347.6 EKX46456.1 - 2.4e-15 56.0 11.4 2.4e-14 52.7 11.4 2.3 1 1 0 1 1 1 1 MFS/sugar transport protein GSHPx PF00255.19 EKX46458.1 - 2.3e-06 27.1 0.0 4.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 EKX46458.1 - 0.0043 17.0 0.1 0.02 14.8 0.0 2.3 2 1 0 2 2 2 1 AhpC/TSA family DUF1077 PF06417.12 EKX46460.1 - 0.11 12.6 0.4 0.19 11.8 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1077) Chloroa_b-bind PF00504.21 EKX46461.1 - 3.9e-14 53.5 0.0 4.5e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein WD40 PF00400.32 EKX46462.1 - 0.039 14.8 0.6 1 10.3 0.2 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat HNH PF01844.23 EKX46463.1 - 2.6e-16 59.5 0.4 3.7e-16 59.0 0.4 1.2 1 0 0 1 1 1 1 HNH endonuclease HNH_5 PF14279.6 EKX46463.1 - 2.5e-15 56.1 0.4 3.4e-15 55.6 0.4 1.2 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 EKX46463.1 - 2.2e-09 37.1 0.1 4.3e-09 36.2 0.1 1.5 1 1 0 1 1 1 1 HNH endonuclease DZR PF12773.7 EKX46463.1 - 0.013 15.5 0.4 0.021 14.8 0.4 1.2 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 EKX46463.1 - 0.048 13.1 3.7 0.28 10.7 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain CENP-F_leu_zip PF10473.9 EKX46464.1 - 0.0073 16.3 6.4 0.0073 16.3 6.4 4.6 3 1 1 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sir1 PF11603.8 EKX46464.1 - 0.021 15.3 1.6 0.041 14.4 1.6 1.4 1 0 0 1 1 1 0 Regulatory protein Sir1 Laminin_II PF06009.12 EKX46464.1 - 4.2 7.4 12.1 0.21 11.6 1.8 3.3 2 2 1 3 3 3 0 Laminin Domain II Pkinase PF00069.25 EKX46465.1 - 7.2e-18 64.9 0.0 1.7e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX46465.1 - 1.7e-16 60.3 0.0 3.2e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 EKX46465.1 - 3.7e-11 43.0 0.4 6.7e-10 39.0 0.2 2.6 2 0 0 2 2 2 1 PX domain TPR_19 PF14559.6 EKX46465.1 - 1.4e-07 31.9 0.2 4.3e-05 23.9 0.4 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX46465.1 - 9.2e-05 23.0 11.0 0.0014 19.3 0.4 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX46465.1 - 0.00035 20.5 7.9 0.002 18.1 0.4 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX46465.1 - 0.00039 20.4 2.2 0.00063 19.8 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX46465.1 - 0.00056 19.6 4.0 0.012 15.5 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Pkinase_fungal PF17667.1 EKX46465.1 - 0.0015 17.4 0.1 0.0015 17.4 0.1 2.4 2 0 0 2 2 2 1 Fungal protein kinase TPR_16 PF13432.6 EKX46465.1 - 0.0038 17.8 0.2 0.0038 17.8 0.2 3.2 4 0 0 4 4 1 1 Tetratricopeptide repeat Hid1 PF12722.7 EKX46465.1 - 0.024 12.8 1.3 0.048 11.8 1.3 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Cas_Csa4 PF09703.10 EKX46465.1 - 0.029 13.7 0.0 0.057 12.7 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa4) TPR_12 PF13424.6 EKX46465.1 - 0.38 11.1 7.0 0.59 10.5 1.2 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat Zip PF02535.22 EKX46465.1 - 0.71 9.0 8.3 0.067 12.4 3.5 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter NPR3 PF03666.13 EKX46465.1 - 2.6 6.8 8.2 5.3 5.7 8.2 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AAA_11 PF13086.6 EKX46465.1 - 4.2 7.1 8.4 0.82 9.4 2.8 2.4 2 0 0 2 2 2 0 AAA domain Cyclin_N PF00134.23 EKX46466.1 - 1.4e-08 34.6 0.1 4.4e-08 32.9 0.1 1.8 1 1 0 1 1 1 1 Cyclin, N-terminal domain FKBP_C PF00254.28 EKX46467.1 - 3.8e-27 94.5 0.0 4.6e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Zn_clus PF00172.18 EKX46468.1 - 1.1e-14 54.2 25.4 7.6e-08 32.4 7.7 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain WW PF00397.26 EKX46469.1 - 4.3e-12 45.9 4.0 6.7e-12 45.3 4.0 1.3 1 0 0 1 1 1 1 WW domain Meckelin PF09773.9 EKX46470.1 - 5.7e-175 583.8 29.1 8.1e-174 580.0 24.6 2.6 1 1 0 1 1 1 1 Meckelin (Transmembrane protein 67) Tme5_EGF_like PF09064.10 EKX46470.1 - 0.29 11.1 15.8 0.11 12.4 0.3 4.0 3 1 1 4 4 4 0 Thrombomodulin like fifth domain, EGF-like BPD_transp_2 PF02653.16 EKX46470.1 - 2.4 7.2 10.2 0.88 8.7 3.0 2.3 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component hEGF PF12661.7 EKX46470.1 - 9.9 7.0 16.1 19 6.1 0.1 4.2 3 0 0 3 3 3 0 Human growth factor-like EGF Dak2 PF02734.17 EKX46471.1 - 0.06 13.2 0.8 0.42 10.5 0.1 2.2 2 0 0 2 2 2 0 DAK2 domain HTH_Tnp_Tc3_1 PF11427.8 EKX46472.1 - 5.4 7.0 6.4 13 5.7 0.1 3.9 4 0 0 4 4 4 0 Tc3 transposase Cpn60_TCP1 PF00118.24 EKX46473.1 - 4.7e-165 549.9 0.8 5.5e-165 549.7 0.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family EF-hand_7 PF13499.6 EKX46476.1 - 0.0058 17.1 0.8 0.12 12.8 0.2 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX46476.1 - 0.0073 16.2 0.0 0.05 13.5 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EKX46476.1 - 0.011 15.2 0.1 0.14 11.8 0.0 2.6 2 0 0 2 2 2 0 EF hand HtrL_YibB PF09612.10 EKX46477.1 - 0.0015 18.1 0.2 0.0045 16.5 0.2 1.7 1 1 0 1 1 1 1 Bacterial protein of unknown function (HtrL_YibB) CarboxypepD_reg PF13620.6 EKX46477.1 - 0.035 14.4 0.0 0.13 12.6 0.0 1.9 3 0 0 3 3 3 0 Carboxypeptidase regulatory-like domain Carbam_trans_C PF16861.5 EKX46477.1 - 0.18 11.4 0.0 0.58 9.7 0.0 1.8 2 0 0 2 2 2 0 Carbamoyltransferase C-terminus LRR_4 PF12799.7 EKX46479.1 - 4.2e-17 62.0 23.2 2.8e-07 30.7 0.2 6.4 4 2 3 7 7 7 5 Leucine Rich repeats (2 copies) EF-hand_1 PF00036.32 EKX46479.1 - 2.5e-15 54.8 9.5 0.00041 19.7 0.0 4.6 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 EKX46479.1 - 9.5e-15 54.8 17.1 3.6e-08 33.7 0.7 3.0 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EKX46479.1 - 1.1e-13 49.9 7.4 0.0019 18.0 0.5 4.4 5 0 0 5 5 4 3 EF-hand domain EF-hand_5 PF13202.6 EKX46479.1 - 1.9e-13 49.3 11.9 0.00014 21.2 0.3 4.5 5 0 0 5 5 5 3 EF hand LRR_8 PF13855.6 EKX46479.1 - 3.2e-13 49.2 20.4 5.3e-05 22.9 0.2 5.4 3 2 4 7 7 7 6 Leucine rich repeat EF-hand_8 PF13833.6 EKX46479.1 - 4.4e-08 32.9 6.1 0.03 14.2 0.1 4.6 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX46479.1 - 1.2e-05 25.6 4.8 0.00046 20.5 0.0 2.9 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region LRR_6 PF13516.6 EKX46479.1 - 0.00016 21.4 20.5 0.54 10.5 0.1 7.0 8 0 0 8 8 8 3 Leucine Rich repeat LRR_1 PF00560.33 EKX46479.1 - 0.00045 20.4 13.5 4.7 8.1 0.6 7.4 6 2 0 6 6 6 1 Leucine Rich Repeat LRR_9 PF14580.6 EKX46479.1 - 0.0085 15.6 8.7 0.21 11.1 0.8 3.6 3 1 0 3 3 3 2 Leucine-rich repeat Dockerin_1 PF00404.18 EKX46479.1 - 0.056 13.6 1.2 21 5.4 0.6 3.4 2 1 1 3 3 3 0 Dockerin type I domain Ank_2 PF12796.7 EKX46480.1 - 3.3e-10 40.4 0.1 4.6e-10 40.0 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX46480.1 - 6.9e-07 29.1 0.0 0.0034 17.7 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EKX46480.1 - 3.8e-05 23.9 0.3 0.095 13.0 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX46480.1 - 0.00031 21.3 0.4 0.039 14.5 0.1 2.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX46480.1 - 0.00045 20.5 0.1 0.15 12.5 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Sigma70_r4 PF04545.16 EKX46481.1 - 0.019 14.5 0.2 0.034 13.7 0.2 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 CENP-B_N PF04218.13 EKX46481.1 - 0.11 12.1 0.4 0.23 11.1 0.2 1.6 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 EKX46481.1 - 0.12 12.1 0.9 0.29 10.9 0.9 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 EKX46482.1 - 0.0033 16.9 0.9 0.018 14.5 0.2 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_38 PF13936.6 EKX46482.1 - 0.049 13.4 1.0 0.16 11.7 1.0 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain CENP-B_N PF04218.13 EKX46482.1 - 0.055 13.1 0.5 0.13 11.9 0.2 1.8 1 1 1 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 EKX46482.1 - 0.11 12.3 0.2 0.39 10.6 0.2 1.9 1 1 0 1 1 1 0 Homeodomain-like domain Sigma70_r4 PF04545.16 EKX46483.1 - 0.019 14.5 0.2 0.034 13.7 0.2 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 CENP-B_N PF04218.13 EKX46483.1 - 0.11 12.1 0.4 0.23 11.1 0.2 1.6 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 EKX46483.1 - 0.12 12.1 0.9 0.29 10.9 0.9 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 EKX46483.1 - 0.63 10.1 3.4 19 5.4 3.4 2.5 1 1 0 1 1 1 0 Winged helix-turn helix Sigma70_r4 PF04545.16 EKX46484.1 - 0.021 14.4 0.2 0.037 13.5 0.2 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 RNHCP PF12647.7 EKX46484.1 - 0.023 14.6 0.3 0.048 13.6 0.3 1.5 1 0 0 1 1 1 0 RNHCP domain CENP-B_N PF04218.13 EKX46484.1 - 0.1 12.2 0.4 0.25 11.0 0.2 1.7 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 EKX46484.1 - 0.14 12.0 0.9 0.32 10.8 0.9 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4 PF04545.16 EKX46485.1 - 0.017 14.6 0.2 0.031 13.8 0.2 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 CENP-B_N PF04218.13 EKX46485.1 - 0.11 12.2 0.4 0.22 11.2 0.4 1.6 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 EKX46485.1 - 0.12 12.2 0.9 0.27 11.0 0.9 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain HEAT_2 PF13646.6 EKX46487.1 - 1.9e-12 47.4 0.2 3.6e-10 40.1 0.2 2.4 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 EKX46487.1 - 1.1e-05 25.2 0.8 0.21 11.9 0.1 4.5 3 1 1 4 4 4 2 HEAT repeat HEAT_PBS PF03130.16 EKX46487.1 - 0.00091 19.7 0.2 0.058 14.1 0.1 3.4 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 EKX46487.1 - 0.024 15.2 3.1 1 9.9 0.0 2.9 2 1 1 3 3 3 0 HEAT-like repeat Arm PF00514.23 EKX46487.1 - 0.061 13.4 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat Spore_III_AB PF09548.10 EKX46487.1 - 0.067 13.3 0.1 0.1 12.7 0.1 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) XG_FTase PF03254.13 EKX46488.1 - 7.7e-05 21.5 0.0 0.00011 20.9 0.0 1.1 1 0 0 1 1 1 1 Xyloglucan fucosyltransferase ArfGap PF01412.18 EKX46489.1 - 9.8e-20 70.8 1.0 1.3e-19 70.4 1.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf HMGL-like PF00682.19 EKX46490.1 - 3.9e-52 177.4 0.0 5.8e-52 176.9 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 EKX46490.1 - 2.3e-06 27.5 0.0 4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain ScdA_N PF04405.14 EKX46490.1 - 0.039 13.6 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown function (DUF542) DSBA PF01323.20 EKX46491.1 - 1.6e-12 47.6 0.0 2.4e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 DSBA-like thioredoxin domain CH PF00307.31 EKX46492.1 - 7.7e-18 64.7 0.0 8.9e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 EKX46492.1 - 0.0012 19.1 0.0 0.0019 18.4 0.0 1.3 1 0 0 1 1 1 1 CDC24 Calponin PPR_2 PF13041.6 EKX46493.1 - 1.5e-28 98.7 5.6 2.2e-05 24.6 0.0 9.3 5 3 4 9 9 9 5 PPR repeat family PPR_3 PF13812.6 EKX46493.1 - 1.7e-23 82.5 0.0 2.4e-05 24.3 0.0 7.2 5 1 2 7 7 7 6 Pentatricopeptide repeat domain PPR_long PF17177.4 EKX46493.1 - 7.2e-14 51.7 6.8 1.5e-07 31.0 0.8 4.7 2 1 2 5 5 5 3 Pentacotripeptide-repeat region of PRORP ECSIT PF06239.11 EKX46493.1 - 0.0047 16.1 0.2 6.9 5.7 0.0 3.8 3 2 1 4 4 4 2 Evolutionarily conserved signalling intermediate in Toll pathway DAHP_snth_FXD PF18152.1 EKX46493.1 - 0.012 15.5 0.1 9.5 6.1 0.0 3.5 3 0 0 3 3 3 0 DAHP synthase ferredoxin-like domain Proteasom_PSMB PF10508.9 EKX46493.1 - 0.018 13.5 0.1 0.032 12.7 0.1 1.3 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit Exog_C PF18026.1 EKX46493.1 - 0.028 14.4 0.6 1.9 8.6 0.1 4.0 4 0 0 4 4 4 0 Endo/exonuclease (EXOG) C-terminal domain EccE PF11203.8 EKX46493.1 - 0.44 10.9 4.2 1.5 9.2 0.7 2.8 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE PPR_1 PF12854.7 EKX46493.1 - 6 6.7 0.0 6 6.7 0.0 8.0 11 0 0 11 11 11 0 PPR repeat eRF1_2 PF03464.15 EKX46494.1 - 5.9e-44 149.6 0.1 1.1e-43 148.7 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EKX46494.1 - 7.6e-36 123.0 0.1 1.7e-35 121.9 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 EKX46494.1 - 2.1e-21 76.3 0.0 3.7e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 EKX46494.1 - 1.1e-08 35.4 0.1 1.8e-08 34.7 0.1 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 EKX46494.1 - 1.4e-08 35.1 0.1 2e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor DUF5643 PF18705.1 EKX46494.1 - 0.069 13.1 0.0 1.1 9.3 0.0 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5643) TMEM65 PF10507.9 EKX46495.1 - 0.092 12.7 0.0 0.1 12.6 0.0 1.0 1 0 0 1 1 1 0 Transmembrane protein 65 His_biosynth PF00977.21 EKX46496.1 - 4.4e-43 147.4 0.6 1.2e-42 146.0 0.6 1.7 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 EKX46496.1 - 1e-16 61.3 0.0 1.6e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 EKX46496.1 - 1.9e-05 24.6 0.0 0.00017 21.5 0.0 2.1 2 0 0 2 2 2 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 EKX46496.1 - 0.00012 21.7 0.0 0.00021 21.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Dus PF01207.17 EKX46496.1 - 0.056 12.5 0.0 0.18 10.9 0.0 1.7 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) FR47 PF08445.10 EKX46496.1 - 0.13 12.3 0.0 1.9 8.5 0.0 2.5 3 0 0 3 3 3 0 FR47-like protein Transcrip_reg PF01709.20 EKX46497.1 - 4e-67 226.1 0.0 4.5e-67 226.0 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator HECT PF00632.25 EKX46500.1 - 2e-68 231.2 0.0 2.2e-68 231.0 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) NifU PF01106.17 EKX46501.1 - 0.073 13.2 0.1 0.31 11.2 0.1 2.0 1 1 0 1 1 1 0 NifU-like domain GP57 PF17594.2 EKX46501.1 - 0.15 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Phage Tail fiber assembly helper gene product 57 SET PF00856.28 EKX46502.1 - 6.1e-05 23.5 0.0 0.00011 22.6 0.0 1.4 1 0 0 1 1 1 1 SET domain LRR_8 PF13855.6 EKX46503.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Leucine rich repeat Endotoxin_N PF03945.14 EKX46504.1 - 0.092 12.4 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain B12D PF06522.11 EKX46504.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.5 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit MethyltransfD12 PF02086.15 EKX46504.1 - 0.16 11.6 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Nop14 PF04147.12 EKX46505.1 - 0.018 13.3 18.1 0.025 12.8 18.1 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EKX46505.1 - 0.045 11.9 32.9 0.066 11.3 32.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC27 PF09507.10 EKX46505.1 - 0.083 12.3 3.5 0.15 11.5 3.5 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SDA1 PF05285.12 EKX46505.1 - 0.66 9.3 20.8 1.1 8.6 20.8 1.3 1 0 0 1 1 1 0 SDA1 DUF2722 PF10846.8 EKX46505.1 - 3.7 6.4 11.3 5.7 5.8 11.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CNDH2_C PF16858.5 EKX46505.1 - 5 6.9 10.9 0.27 11.1 5.1 1.9 2 1 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term IFT57 PF10498.9 EKX46505.1 - 9.2 5.1 9.5 2.7 6.9 6.8 1.4 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 CobT PF06213.12 EKX46505.1 - 9.8 5.5 21.6 7.7 5.8 18.1 2.0 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Peptidase_M48 PF01435.18 EKX46506.1 - 6.6e-22 78.3 0.0 1.1e-21 77.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Zn_peptidase_2 PF04298.12 EKX46506.1 - 0.2 11.1 0.6 0.39 10.1 0.6 1.4 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase DUF2268 PF10026.9 EKX46506.1 - 0.21 11.2 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) DUF3136 PF11334.8 EKX46509.1 - 0.13 12.1 1.0 13 5.7 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3136) BaxI_1 PF12811.7 EKX46509.1 - 0.71 9.4 6.8 0.38 10.3 0.3 2.9 3 0 0 3 3 3 0 Bax inhibitor 1 like ADH_zinc_N_2 PF13602.6 EKX46510.1 - 1.4e-22 81.2 0.0 2.5e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EKX46510.1 - 9.4e-15 54.7 0.2 3.4e-14 52.9 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EKX46510.1 - 4.3e-09 36.2 0.0 3.3e-07 30.2 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.24 EKX46510.1 - 0.00096 19.6 0.0 0.0015 19.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.18 EKX46510.1 - 0.0077 16.5 0.0 0.43 10.9 0.0 2.9 1 1 1 2 2 2 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 EKX46510.1 - 0.058 13.7 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain PUF PF00806.19 EKX46510.1 - 0.14 11.9 0.1 0.37 10.6 0.1 1.7 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat LMF1 PF06762.14 EKX46511.1 - 2.2e-94 317.1 3.6 1.4e-53 182.6 7.8 2.4 1 1 0 2 2 2 2 Lipase maturation factor Trefoil PF00088.18 EKX46513.1 - 0.017 15.0 9.4 0.046 13.6 9.5 1.8 1 1 0 1 1 1 0 Trefoil (P-type) domain tRNA_m1G_MT PF01746.21 EKX46514.1 - 0.12 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase LRR_6 PF13516.6 EKX46516.1 - 8.8e-50 162.6 44.5 0.00054 19.8 0.1 15.9 16 0 0 16 16 16 15 Leucine Rich repeat LRR_4 PF12799.7 EKX46516.1 - 7.3e-17 61.2 21.1 0.0036 17.7 0.5 8.7 6 3 3 10 10 10 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX46516.1 - 1.9e-07 30.7 34.6 0.053 13.3 1.5 9.5 7 5 2 9 9 9 6 Leucine rich repeat LRR_1 PF00560.33 EKX46516.1 - 0.0002 21.5 30.0 0.74 10.6 0.1 11.1 13 1 0 13 13 13 2 Leucine Rich Repeat LRR_2 PF07723.13 EKX46516.1 - 0.049 14.3 0.2 13 6.6 0.1 4.4 3 0 0 3 3 3 0 Leucine Rich Repeat DUF3136 PF11334.8 EKX46517.1 - 0.27 11.0 0.8 34 4.3 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3136) NMD3 PF04981.13 EKX46518.1 - 5.5e-74 248.7 3.9 5.5e-74 248.7 3.9 1.4 2 0 0 2 2 2 1 NMD3 family Nif11 PF07862.11 EKX46518.1 - 0.00037 20.7 0.1 0.00089 19.5 0.1 1.7 1 0 0 1 1 1 1 Nif11 domain OrfB_Zn_ribbon PF07282.11 EKX46518.1 - 0.13 12.2 1.6 12 5.9 0.1 3.3 3 0 0 3 3 3 0 Putative transposase DNA-binding domain DZR PF12773.7 EKX46518.1 - 8.8 6.4 7.2 2.3e+02 1.9 7.2 2.7 1 1 0 1 1 1 0 Double zinc ribbon Rif1_N PF12231.8 EKX46519.1 - 2.6e-26 92.5 5.7 6.1e-26 91.3 5.7 1.6 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal HEAT PF02985.22 EKX46519.1 - 0.053 13.8 0.2 22 5.7 0.0 4.9 4 0 0 4 4 4 0 HEAT repeat zf-HC5HC2H_2 PF13832.6 EKX46520.1 - 9.2e-22 77.3 1.5 1.2e-21 76.9 1.5 1.2 1 1 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EKX46520.1 - 8.3e-16 58.0 2.1 1.2e-15 57.5 2.1 1.3 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD_2 PF13831.6 EKX46520.1 - 3.7e-05 23.2 0.3 3.7e-05 23.2 0.3 3.0 3 0 0 3 3 3 1 PHD-finger PHD PF00628.29 EKX46520.1 - 6.1e-05 22.8 10.2 0.0059 16.5 3.2 2.7 3 0 0 3 3 3 2 PHD-finger C1_2 PF03107.16 EKX46520.1 - 0.041 14.2 1.2 0.041 14.2 1.2 2.9 3 0 0 3 3 3 0 C1 domain zf-RING_2 PF13639.6 EKX46520.1 - 0.094 13.1 2.4 0.094 13.1 2.4 2.5 3 1 1 4 4 4 0 Ring finger domain SNF2_N PF00176.23 EKX46521.1 - 4.5e-66 222.9 0.0 7.4e-66 222.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX46521.1 - 3.1e-19 69.3 0.0 5.6e-18 65.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX46521.1 - 7.1e-06 26.1 0.0 3e-05 24.1 0.0 2.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EKX46521.1 - 1.1e-05 25.3 0.0 2.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 EKX46521.1 - 3e-05 23.3 0.0 0.00011 21.5 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 EKX46521.1 - 0.013 15.2 0.1 0.041 13.6 0.1 1.9 1 1 0 1 1 1 0 SWI2/SNF2 ATPase AAA_34 PF13872.6 EKX46521.1 - 0.052 12.4 0.2 0.2 10.5 0.2 1.8 1 1 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 PhoH PF02562.16 EKX46521.1 - 0.069 12.6 0.0 0.44 10.0 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein EF-hand_7 PF13499.6 EKX46522.1 - 0.1 13.1 0.0 0.17 12.4 0.0 1.4 1 1 0 1 1 1 0 EF-hand domain pair ADH_zinc_N PF00107.26 EKX46524.1 - 1.7e-11 44.2 0.0 7.3e-11 42.2 0.0 2.0 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EKX46524.1 - 2.1e-08 35.3 0.0 6.1e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.8 EKX46524.1 - 0.0039 16.9 0.8 0.023 14.4 0.9 2.0 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase YjeF_N PF03853.15 EKX46524.1 - 0.0051 16.7 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus AlaDh_PNT_C PF01262.21 EKX46524.1 - 0.017 14.5 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Hyaluronidase_1 PF07212.11 EKX46524.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Hyaluronidase protein (HylP) Glu_dehyd_C PF16912.5 EKX46524.1 - 0.17 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 EKX46524.1 - 0.18 11.1 0.1 0.37 10.1 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Bac_rhodopsin PF01036.18 EKX46526.1 - 1e-38 133.2 27.0 1.2e-38 132.9 27.0 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein STAG PF08514.11 EKX46527.1 - 3e-07 30.3 4.2 2.4e-06 27.4 0.8 3.4 2 1 0 2 2 2 1 STAG domain HEAT PF02985.22 EKX46527.1 - 0.0053 16.9 0.8 0.58 10.6 0.0 4.1 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 EKX46527.1 - 0.0082 16.5 0.0 0.79 10.2 0.0 3.8 3 1 1 4 4 4 1 HEAT repeats APOBEC_C PF05240.14 EKX46527.1 - 0.062 13.3 1.2 0.17 11.9 0.1 2.3 2 0 0 2 2 2 0 APOBEC-like C-terminal domain Pan3_PK PF18101.1 EKX46528.1 - 5.2e-51 172.2 0.0 9.6e-51 171.4 0.0 1.5 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 EKX46528.1 - 0.0015 17.9 0.1 0.0024 17.3 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Thioredoxin_13 PF18401.1 EKX46530.1 - 0.0013 18.7 0.1 0.0027 17.6 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain TFIIA PF03153.13 EKX46530.1 - 0.56 10.1 14.3 0.72 9.8 14.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Uds1 PF15456.6 EKX46530.1 - 3.8 7.7 9.2 1.3 9.2 6.4 1.6 2 0 0 2 2 2 0 Up-regulated During Septation zf-B_box PF00643.24 EKX46531.1 - 4.5e-05 23.5 3.1 4.5e-05 23.5 3.1 4.0 4 0 0 4 4 4 2 B-box zinc finger zf-RING_5 PF14634.6 EKX46531.1 - 0.021 14.8 9.0 0.021 14.8 9.0 3.8 4 0 0 4 4 4 0 zinc-RING finger domain DUF3958 PF13125.6 EKX46531.1 - 0.23 11.7 4.2 0.59 10.4 0.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3958) UPF0184 PF03670.13 EKX46531.1 - 0.75 10.2 5.5 0.9 10.0 1.3 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) zf-RING_UBOX PF13445.6 EKX46531.1 - 1.4 9.0 20.5 0.22 11.6 8.5 3.8 4 0 0 4 4 4 0 RING-type zinc-finger TruD PF01142.18 EKX46532.1 - 2.9e-54 184.5 0.0 8.3e-50 169.8 0.0 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Fz PF01392.22 EKX46533.1 - 0.02 15.5 11.8 0.02 15.5 1.0 2.5 2 0 0 2 2 2 0 Fz domain WD40 PF00400.32 EKX46534.1 - 6.3e-21 74.3 11.3 1.6e-05 25.6 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 EKX46534.1 - 6.8e-10 39.1 0.4 1.8e-09 37.7 0.4 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex LVIVD PF08309.11 EKX46534.1 - 0.2 11.0 0.7 0.49 9.8 0.7 1.6 1 0 0 1 1 1 0 LVIVD repeat Methyltransf_31 PF13847.6 EKX46535.1 - 9.4e-13 48.2 0.1 1.9e-12 47.2 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX46535.1 - 5.9e-12 46.1 0.4 1.6e-11 44.8 0.1 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX46535.1 - 8.1e-11 42.0 0.0 1.9e-10 40.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX46535.1 - 8.3e-11 42.4 0.7 2.3e-10 41.0 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX46535.1 - 1.4e-07 32.2 0.1 3.8e-07 30.8 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX46535.1 - 4.7e-05 22.8 0.4 0.00064 19.1 0.1 2.1 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EKX46535.1 - 0.00016 21.7 0.0 0.00031 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EKX46535.1 - 0.00027 20.5 0.0 0.0005 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 EKX46535.1 - 0.0031 17.1 0.1 0.01 15.5 0.1 1.8 1 1 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.13 EKX46535.1 - 0.023 14.1 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_33 PF10017.9 EKX46535.1 - 0.044 12.9 0.0 0.33 10.0 0.0 2.3 1 1 1 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent Bmt2 PF11968.8 EKX46535.1 - 0.097 12.5 0.0 0.23 11.3 0.0 1.6 2 0 0 2 2 2 0 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 PDZ PF00595.24 EKX46538.1 - 9.9e-06 25.8 0.0 2.6e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX46538.1 - 0.00058 19.7 0.0 0.0025 17.6 0.0 2.1 2 0 0 2 2 2 1 PDZ domain MAD PF05557.13 EKX46538.1 - 0.001 17.6 6.3 0.0015 17.0 6.3 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein GAS PF13851.6 EKX46538.1 - 0.0011 18.4 7.4 0.0021 17.5 7.4 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding OmpH PF03938.14 EKX46538.1 - 0.15 12.3 10.2 0.33 11.3 10.2 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) UPF0242 PF06785.11 EKX46538.1 - 0.21 11.7 3.3 0.47 10.5 3.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Prefoldin_2 PF01920.20 EKX46538.1 - 0.35 10.8 7.8 0.88 9.6 4.7 2.5 2 0 0 2 2 2 0 Prefoldin subunit SYCE1 PF15233.6 EKX46538.1 - 1.2 9.2 11.6 2.8 8.0 9.4 2.2 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 DUF4407 PF14362.6 EKX46538.1 - 2.3 7.5 8.9 3.9 6.8 8.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CALM_bind PF16025.5 EKX46538.1 - 2.3 8.7 6.3 6.4 7.3 6.3 1.8 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding Spc7 PF08317.11 EKX46538.1 - 2.9 6.7 10.3 5.4 5.8 10.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein NAD_binding_2 PF03446.15 EKX46539.1 - 5.9e-40 137.0 0.0 8e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EKX46539.1 - 3.3e-35 121.0 0.0 5.5e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Pkinase PF00069.25 EKX46540.1 - 2.8e-13 49.8 0.0 1.3e-12 47.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX46540.1 - 4.3e-07 29.5 0.0 8.1e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Amidase PF01425.21 EKX46542.1 - 2.2e-43 148.9 0.1 2e-26 93.0 0.0 3.8 2 1 1 3 3 3 3 Amidase NCA2 PF08637.10 EKX46542.1 - 0.035 13.3 0.3 0.12 11.5 0.0 1.8 2 0 0 2 2 2 0 ATP synthase regulation protein NCA2 Choline_kinase PF01633.20 EKX46545.1 - 8.5e-38 130.1 0.0 3.6e-33 115.0 0.0 2.2 2 0 0 2 2 2 2 Choline/ethanolamine kinase APH PF01636.23 EKX46545.1 - 1.8e-11 44.4 0.0 4.8e-11 43.0 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EKX46545.1 - 3.9e-05 23.1 0.1 5.5e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase Haspin_kinase PF12330.8 EKX46545.1 - 0.0015 17.5 0.0 0.0027 16.7 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain HEAT_2 PF13646.6 EKX46546.1 - 4.8e-21 75.0 16.4 2.9e-08 34.0 0.1 5.4 3 2 3 6 6 6 4 HEAT repeats HEAT PF02985.22 EKX46546.1 - 4e-16 57.7 7.8 0.0085 16.3 0.0 6.9 7 0 0 7 7 7 4 HEAT repeat Cnd1 PF12717.7 EKX46546.1 - 8.2e-06 26.0 2.0 0.2 11.7 0.1 4.0 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EKX46546.1 - 0.00016 22.1 8.4 5.5 7.6 0.1 5.2 5 0 0 5 5 4 3 HEAT-like repeat IFRD PF05004.13 EKX46546.1 - 0.014 14.5 3.7 0.015 14.5 0.1 2.8 3 1 0 3 3 3 0 Interferon-related developmental regulator (IFRD) V-ATPase_H_C PF11698.8 EKX46546.1 - 0.029 14.5 0.5 4.5 7.4 0.0 3.9 5 0 0 5 5 5 0 V-ATPase subunit H Adaptin_N PF01602.20 EKX46546.1 - 0.066 11.8 3.4 0.16 10.5 0.1 2.5 3 1 0 3 3 3 0 Adaptin N terminal region Arm PF00514.23 EKX46546.1 - 0.073 13.1 2.0 19 5.5 0.0 4.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat RasGEF_N_2 PF14663.6 EKX46546.1 - 0.11 12.9 0.1 3.7 8.0 0.0 3.3 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain MIP-T3 PF10243.9 EKX46546.1 - 0.13 12.2 0.4 0.35 10.9 0.4 1.7 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CH-like domain Terminase_2 PF03592.16 EKX46546.1 - 0.55 10.7 3.0 8.6 6.8 1.1 2.8 2 0 0 2 2 2 0 Terminase small subunit Cohesin_HEAT PF12765.7 EKX46546.1 - 0.56 10.6 2.7 50 4.3 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion ALF PF03752.13 EKX46546.1 - 2.3 8.2 6.4 41 4.2 0.1 4.1 4 0 0 4 4 4 0 Short repeats of unknown function PRA-PH PF01503.17 EKX46547.1 - 2.6e-14 53.4 0.0 4.9e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase PRA-CH PF01502.18 EKX46547.1 - 5.3e-12 45.4 0.2 9.9e-12 44.5 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase MazG-like PF12643.7 EKX46547.1 - 0.017 15.4 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 MazG-like family MazG PF03819.17 EKX46547.1 - 0.057 13.6 0.3 0.26 11.5 0.0 2.0 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain PreAtp-grasp PF18604.1 EKX46547.1 - 0.11 12.2 0.0 0.42 10.3 0.0 1.9 2 0 0 2 2 2 0 Pre ATP-grasp domain MORN PF02493.20 EKX46550.1 - 7e-68 220.7 86.8 2.4e-07 30.2 0.5 13.9 14 0 0 14 14 14 12 MORN repeat ID PF18543.1 EKX46550.1 - 0.076 13.0 11.8 10 6.3 0.0 6.3 5 2 2 7 7 7 0 Intracellular delivery domain Caf4 PF11615.8 EKX46550.1 - 0.22 11.5 0.0 41 4.2 0.0 2.6 2 1 0 2 2 2 0 CCR4-associated factor 4 Rxt3 PF08642.10 EKX46551.1 - 1.4e-10 42.0 0.5 2.8e-08 34.6 0.0 2.3 1 1 1 2 2 2 2 Histone deacetylation protein Rxt3 LCCL PF03815.19 EKX46551.1 - 5.6e-07 29.6 0.0 1.3e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 LCCL domain Histidinol_dh PF00815.20 EKX46552.1 - 7.3e-132 440.2 4.8 8.9e-132 440.0 4.8 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase DUF4363 PF14276.6 EKX46553.1 - 0.081 13.0 1.4 0.13 12.4 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) DNA_RNApol_7kD PF03604.13 EKX46554.1 - 0.2 11.3 0.1 0.51 10.1 0.1 1.6 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit GT-D PF08759.11 EKX46555.1 - 6.5e-06 26.0 0.0 0.046 13.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase GT-D fold PDZ_2 PF13180.6 EKX46556.1 - 0.0014 18.9 0.0 0.0028 18.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Auxin_inducible PF02519.14 EKX46556.1 - 0.0072 16.5 0.0 0.028 14.6 0.0 2.0 1 1 1 2 2 2 1 Auxin responsive protein Nucleoside_tran PF01733.18 EKX46556.1 - 0.012 15.0 0.5 0.018 14.4 0.5 1.2 1 0 0 1 1 1 0 Nucleoside transporter PDZ_6 PF17820.1 EKX46556.1 - 0.014 15.3 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 PDZ domain MIF4G_like_2 PF09090.11 EKX46556.1 - 0.042 13.3 3.8 0.076 12.5 3.8 1.3 1 0 0 1 1 1 0 MIF4G like FAM176 PF14851.6 EKX46556.1 - 0.4 10.4 7.9 0.055 13.1 3.8 1.7 2 0 0 2 2 2 0 FAM176 family Paf1 PF03985.13 EKX46556.1 - 1.9 7.4 12.2 3.7 6.4 12.2 1.4 1 0 0 1 1 1 0 Paf1 DUF1682 PF07946.14 EKX46556.1 - 1.9 7.6 6.2 3.1 6.9 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DNA_pol_phi PF04931.13 EKX46556.1 - 6.1 4.8 10.2 8.8 4.3 10.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Ste5_C PF12194.8 EKX46557.1 - 2.5 8.0 8.0 0.36 10.8 3.3 1.8 2 0 0 2 2 2 0 Protein kinase Fus3-binding Ion_trans PF00520.31 EKX46558.1 - 6.4e-82 274.5 32.8 9.1e-39 133.2 10.2 3.2 3 0 0 3 3 3 3 Ion transport protein Ion_trans PF00520.31 EKX46559.1 - 5.5e-20 71.6 17.7 3.3e-19 69.1 17.7 2.0 1 1 0 1 1 1 1 Ion transport protein Malt_amylase_C PF16657.5 EKX46559.1 - 0.17 12.0 0.0 0.43 10.7 0.0 1.6 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain Syntaxin_2 PF14523.6 EKX46560.1 - 0.011 16.1 1.2 0.011 16.1 1.2 2.2 2 1 0 2 2 2 0 Syntaxin-like protein Lipase_GDSL_lke PF16255.5 EKX46560.1 - 0.023 14.0 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase SHD1 PF03983.12 EKX46560.1 - 0.074 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 SLA1 homology domain 1, SHD1 LON_substr_bdg PF02190.16 EKX46560.1 - 0.56 10.0 6.8 17 5.2 6.6 2.4 1 1 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain Col_cuticle_N PF01484.17 EKX46560.1 - 6.5 6.9 8.7 2 8.6 0.1 3.3 3 0 0 3 3 3 0 Nematode cuticle collagen N-terminal domain Lipase_GDSL_2 PF13472.6 EKX46561.1 - 2.4e-09 37.9 0.2 4.9e-08 33.6 0.2 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF5104 PF17117.5 EKX46562.1 - 1.5 9.3 4.3 2.6 8.5 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5104) Lactamase_B_4 PF13691.6 EKX46563.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 tRNase Z endonuclease TPP1 PF10341.9 EKX46565.1 - 0.073 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Shelterin complex subunit, TPP1/ACD CAC1F_C PF16885.5 EKX46565.1 - 0.58 9.8 15.7 0.91 9.1 15.7 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term SRP-alpha_N PF04086.13 EKX46565.1 - 2.2 8.1 23.2 3.3 7.5 23.2 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ribosomal_L24e PF01246.20 EKX46568.1 - 4.3e-28 97.3 1.3 4.3e-28 97.3 1.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e Phage_X PF05155.15 EKX46568.1 - 0.037 14.5 0.2 0.077 13.4 0.2 1.6 1 1 0 1 1 1 0 Phage X family Xan_ur_permease PF00860.20 EKX46569.1 - 1e-60 205.5 26.5 2.1e-38 132.1 14.3 2.0 2 0 0 2 2 2 2 Permease family MFS_MOT1 PF16983.5 EKX46569.1 - 0.0021 18.4 23.1 0.021 15.2 6.1 3.6 3 1 0 3 3 3 2 Molybdate transporter of MFS superfamily FKBP_C PF00254.28 EKX46570.1 - 6e-16 58.6 0.0 8.5e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Seipin PF06775.14 EKX46571.1 - 3.2e-34 118.8 0.2 4.5e-34 118.3 0.2 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Myc_target_1 PF15179.6 EKX46571.1 - 0.037 13.9 0.2 0.089 12.7 0.2 1.6 1 0 0 1 1 1 0 Myc target protein 1 Fructosamin_kin PF03881.14 EKX46572.1 - 8e-75 251.7 0.0 9.7e-75 251.4 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EKX46572.1 - 0.0013 18.7 0.0 0.0017 18.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-RanBP PF00641.18 EKX46573.1 - 1.5e-13 49.8 49.0 0.00013 21.2 6.7 5.3 5 0 0 5 5 5 4 Zn-finger in Ran binding protein and others Antimicrobial17 PF08129.11 EKX46573.1 - 2.3e-05 24.3 0.9 18 5.4 0.0 5.6 6 0 0 6 6 6 1 Alpha/beta enterocin family DNA_pol_B_N PF18094.1 EKX46573.1 - 0.013 16.0 5.9 13 6.4 0.1 3.2 3 0 0 3 3 3 0 DNA polymerase beta N-terminal domain zinc_ribbon_10 PF10058.9 EKX46573.1 - 0.099 12.4 12.6 6.3 6.6 0.1 4.0 4 0 0 4 4 4 0 Predicted integral membrane zinc-ribbon metal-binding protein NPCBM_assoc PF10633.9 EKX46573.1 - 0.1 12.9 1.9 35 4.7 0.0 3.2 3 0 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase PP_M1 PF03012.14 EKX46573.1 - 0.47 9.9 20.2 0.018 14.6 7.7 2.1 1 1 1 2 2 2 0 Phosphoprotein NPR1_interact PF15699.5 EKX46573.1 - 3.7 8.2 23.7 9.8 6.9 5.0 3.3 3 0 0 3 3 3 0 NPR1 interacting WRNPLPNID PF15017.6 EKX46573.1 - 5.4 8.0 32.1 6.7 7.7 6.4 3.5 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box SET PF00856.28 EKX46574.1 - 9.7e-06 26.1 0.0 2.7e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 SET domain Glyco_hydro_130 PF04041.13 EKX46575.1 - 0.00068 18.7 0.0 5.5 5.8 0.0 3.2 2 1 0 2 2 2 2 beta-1,4-mannooligosaccharide phosphorylase Glyco_hydro_32N PF00251.20 EKX46575.1 - 0.0067 16.0 0.4 0.69 9.4 0.0 2.4 2 1 0 3 3 3 2 Glycosyl hydrolases family 32 N-terminal domain DUF3984 PF13136.6 EKX46576.1 - 0.069 12.5 0.1 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3984) TPR_MLP1_2 PF07926.12 EKX46578.1 - 0.018 15.1 10.1 0.018 15.1 10.1 4.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein HU-CCDC81_bac_2 PF18175.1 EKX46578.1 - 0.96 9.4 5.1 0.54 10.2 0.9 2.7 2 1 1 3 3 3 0 CCDC81-like prokaryotic HU domain 2 GAS PF13851.6 EKX46578.1 - 1.5 8.1 47.3 0.047 13.0 15.5 3.5 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 EKX46578.1 - 9.7 6.4 53.5 0.92 9.7 10.2 3.4 2 1 2 4 4 4 0 JNK_SAPK-associated protein-1 FKBP_C PF00254.28 EKX46579.1 - 1.1e-23 83.4 0.0 1.4e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Thioredoxin PF00085.20 EKX46580.1 - 8.1e-18 64.3 0.1 1.1e-17 63.8 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EKX46580.1 - 1.4e-07 31.9 0.0 2.1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 EKX46580.1 - 6e-07 29.5 0.0 7.8e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 EKX46580.1 - 0.0023 18.2 0.0 0.0041 17.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.6 EKX46580.1 - 0.0071 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.21 EKX46580.1 - 0.018 15.0 0.1 0.046 13.7 0.1 1.6 1 1 0 1 1 1 0 AhpC/TSA family Thioredoxin_7 PF13899.6 EKX46580.1 - 0.019 15.1 0.1 0.031 14.4 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like OST3_OST6 PF04756.13 EKX46580.1 - 0.023 14.0 0.0 0.033 13.5 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_6 PF13848.6 EKX46580.1 - 0.068 13.1 0.0 0.077 12.9 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain Mito_carr PF00153.27 EKX46581.1 - 6e-68 224.8 1.8 7.4e-27 93.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 EKX46581.1 - 0.071 13.3 0.0 2.4 8.4 0.0 2.8 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase LAP1C PF05609.12 EKX46582.1 - 0.0019 17.4 3.1 0.0019 17.4 3.1 2.2 1 1 1 2 2 2 1 Lamina-associated polypeptide 1C (LAP1C) DUF4400 PF14348.6 EKX46582.1 - 0.0061 16.1 4.4 0.013 15.1 4.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4400) DUF3043 PF11241.8 EKX46582.1 - 0.02 14.9 9.9 0.02 14.9 9.9 3.3 3 1 0 3 3 1 0 Protein of unknown function (DUF3043) DUF1385 PF07136.11 EKX46582.1 - 0.13 11.5 6.0 0.2 10.9 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) FA_desaturase PF00487.24 EKX46582.1 - 0.19 11.5 1.4 0.26 11.1 1.4 1.2 1 0 0 1 1 1 0 Fatty acid desaturase DUF2207 PF09972.9 EKX46582.1 - 0.22 10.2 3.3 0.37 9.5 3.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1700 PF08006.11 EKX46582.1 - 0.34 10.4 9.4 0.59 9.6 9.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) BUD22 PF09073.10 EKX46582.1 - 0.39 10.0 27.0 0.69 9.2 27.0 1.4 1 0 0 1 1 1 0 BUD22 Ac81 PF05820.11 EKX46582.1 - 0.54 9.8 3.9 0.78 9.3 3.9 1.2 1 0 0 1 1 1 0 Baculoviridae AC81 PRA1 PF03208.19 EKX46582.1 - 0.78 9.4 12.2 1.2 8.8 12.2 1.2 1 0 0 1 1 1 0 PRA1 family protein DUF4349 PF14257.6 EKX46582.1 - 1 8.8 7.3 2.4 7.5 7.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) ATP-synt_S1 PF05827.12 EKX46583.1 - 2.1e-07 30.8 0.5 4.7e-07 29.8 0.5 1.6 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) YibE_F PF07907.11 EKX46583.1 - 0.003 17.1 4.9 0.003 17.1 4.9 1.3 2 0 0 2 2 2 1 YibE/F-like protein GPR15L PF15854.5 EKX46583.1 - 0.13 12.5 0.1 0.94 9.8 0.0 2.1 2 0 0 2 2 2 0 G-protein coupled receptor ligand 15 DUF4131 PF13567.6 EKX46583.1 - 3.9 7.1 6.1 4.2 7.0 1.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Eapp_C PF10238.9 EKX46584.1 - 6.8e-11 42.5 1.6 6.8e-11 42.5 1.6 2.7 4 0 0 4 4 4 1 E2F-associated phosphoprotein Thioredoxin_6 PF13848.6 EKX46584.1 - 1.2e-06 28.6 0.0 0.0061 16.5 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like domain Golgin_A5 PF09787.9 EKX46584.1 - 0.0078 15.7 8.2 0.0078 15.7 8.2 3.6 4 0 0 4 4 4 1 Golgin subfamily A member 5 Spc7 PF08317.11 EKX46584.1 - 0.033 13.1 25.9 0.0088 15.0 8.3 3.5 3 0 0 3 3 3 0 Spc7 kinetochore protein ERp29_N PF07912.13 EKX46584.1 - 0.084 13.0 0.0 2.7 8.1 0.0 2.4 2 0 0 2 2 2 0 ERp29, N-terminal domain Synaptobrevin PF00957.21 EKX46584.1 - 0.37 10.6 4.3 3.1 7.7 0.4 3.0 2 0 0 2 2 2 0 Synaptobrevin T3SSipB PF16535.5 EKX46584.1 - 0.88 10.0 10.8 2.5 8.6 4.6 2.9 2 0 0 2 2 2 0 Type III cell invasion protein SipB Cor1 PF04803.12 EKX46584.1 - 2.3 8.4 7.9 8.6 6.6 0.8 3.3 3 0 0 3 3 3 0 Cor1/Xlr/Xmr conserved region CENP-F_leu_zip PF10473.9 EKX46584.1 - 4 7.5 42.0 19 5.3 0.0 5.4 4 1 1 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HMMR_N PF15905.5 EKX46584.1 - 4.2 6.7 20.8 0.015 14.8 6.5 3.2 3 0 0 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Prominin PF05478.11 EKX46584.1 - 5.1 4.9 6.8 13 3.6 0.2 2.5 2 0 0 2 2 2 0 Prominin Muted PF14942.6 EKX46584.1 - 6.8 7.0 16.9 1.8 8.9 4.6 3.9 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein Ala_racemase_N PF01168.20 EKX46585.1 - 2e-21 76.7 0.0 2.6e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DHQS PF01959.16 EKX46585.1 - 0.062 12.2 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 3-dehydroquinate synthase II DUF2054 PF10218.9 EKX46586.1 - 7.3e-34 116.7 22.9 7.3e-34 116.7 22.9 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2054) Glyco_transf_18 PF15024.6 EKX46586.1 - 9.6e-07 27.8 1.2 1.5e-06 27.1 1.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 18 UVR PF02151.19 EKX46587.1 - 4.4e-06 26.2 0.1 8.1e-06 25.4 0.1 1.4 1 0 0 1 1 1 1 UvrB/uvrC motif Response_reg PF00072.24 EKX46590.1 - 1.1e-31 109.3 0.2 1.3e-31 109.1 0.2 1.0 1 0 0 1 1 1 1 Response regulator receiver domain OKR_DC_1_N PF03709.15 EKX46590.1 - 0.17 12.1 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain PAS PF00989.25 EKX46591.1 - 0 1090.9 29.9 4e-24 84.8 0.0 15.2 15 0 0 15 15 15 15 PAS fold PAS_4 PF08448.10 EKX46591.1 - 3.2e-191 622.8 2.8 1.3e-13 51.2 0.0 15.2 15 0 0 15 15 15 15 PAS fold PAS_9 PF13426.7 EKX46591.1 - 5.4e-184 598.6 53.4 3.4e-14 53.0 0.1 15.3 15 0 0 15 15 15 15 PAS domain PAS_3 PF08447.12 EKX46591.1 - 8.1e-112 365.8 0.0 1.1e-07 32.0 0.0 15.5 15 0 0 15 15 15 15 PAS fold PAS_8 PF13188.7 EKX46591.1 - 1.6e-85 280.1 22.9 1.8e-05 24.6 0.0 14.6 14 0 0 14 14 14 14 PAS domain HATPase_c PF02518.26 EKX46591.1 - 1.2e-28 99.9 0.7 2.3e-26 92.5 0.0 4.3 4 0 0 4 4 4 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EKX46591.1 - 1e-26 93.3 0.2 2.7e-26 91.9 0.2 1.8 1 0 0 1 1 1 1 Response regulator receiver domain PAS_10 PF13596.6 EKX46591.1 - 1.2e-25 90.1 34.7 0.0046 17.5 0.0 14.0 14 0 0 14 14 14 6 PAS domain HisKA PF00512.25 EKX46591.1 - 2.5e-18 65.9 2.4 1.8e-17 63.1 0.4 3.5 3 0 0 3 3 2 1 His Kinase A (phospho-acceptor) domain bacHORMA_2 PF18173.1 EKX46591.1 - 1.2e-08 35.0 1.1 42 3.9 0.0 10.2 12 0 0 12 12 12 0 Bacterial HORMA domain 2 Y_phosphatase2 PF03162.13 EKX46591.1 - 4.1e-08 33.0 0.0 24 4.5 0.0 10.5 13 0 0 13 13 12 0 Tyrosine phosphatase family DUF1824 PF08854.10 EKX46591.1 - 1.7e-07 31.2 10.2 50 3.8 0.0 11.5 13 0 0 13 13 13 0 Domain of unknown function (DUF1824) sCache_3_3 PF17202.4 EKX46591.1 - 6.7e-05 23.3 24.2 1.1e+02 3.3 0.0 12.8 14 0 0 14 14 14 0 Single cache domain 3 DUF5588 PF17826.1 EKX46591.1 - 0.00012 21.1 4.1 15 4.3 0.0 7.3 9 0 0 9 9 9 0 Family of unknown function (DUF5588) ProQ PF04352.13 EKX46591.1 - 0.0023 17.8 16.4 4.9 7.1 0.0 9.2 11 0 0 11 11 11 2 ProQ/FINO family HATPase_c_3 PF13589.6 EKX46591.1 - 0.016 15.1 0.0 0.2 11.5 0.0 2.8 3 0 0 3 3 3 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ESSS PF10183.9 EKX46591.1 - 0.029 14.6 3.8 1.4e+02 2.8 0.0 7.4 11 0 0 11 11 8 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) TMEM210 PF15195.6 EKX46591.1 - 0.053 13.9 2.9 1.1e+02 3.3 0.0 5.4 6 0 0 6 6 4 0 TMEM210 family dCache_1 PF02743.18 EKX46591.1 - 0.63 9.8 12.4 24 4.6 0.2 7.1 5 2 3 8 8 8 0 Cache domain GARS_C PF02843.16 EKX46591.1 - 5.1 7.4 17.6 2.4 8.5 0.0 7.5 10 0 0 10 10 7 0 Phosphoribosylglycinamide synthetase, C domain Cache_3-Cache_2 PF17201.4 EKX46591.1 - 8.4 5.6 26.9 67 2.6 0.0 10.3 13 0 0 13 13 13 0 Cache 3/Cache 2 fusion domain Rhodanese PF00581.20 EKX46592.1 - 6.4e-18 65.2 0.0 9.8e-09 35.7 0.0 3.1 2 1 1 3 3 3 3 Rhodanese-like domain DotA PF11388.8 EKX46594.1 - 0.11 12.8 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Phagosome trafficking protein DotA TraB PF01963.17 EKX46595.1 - 7.1e-13 49.0 0.0 1.2e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 TraB family PDZ_6 PF17820.1 EKX46596.1 - 2.6e-09 36.8 0.5 5.7e-09 35.7 0.5 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX46596.1 - 2.6e-07 30.9 0.5 7e-07 29.5 0.5 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX46596.1 - 7e-06 26.3 0.2 2.1e-05 24.8 0.2 1.8 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX46596.1 - 0.0006 19.7 0.1 0.0019 18.1 0.1 1.9 1 0 0 1 1 1 1 Tricorn protease PDZ domain Cdh1_DBD_1 PF18196.1 EKX46596.1 - 2.6 8.4 7.0 2.1 8.7 3.5 2.6 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 Mito_carr PF00153.27 EKX46597.1 - 1e-66 220.9 3.4 1.1e-21 76.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein 2OG-FeII_Oxy_3 PF13640.6 EKX46598.1 - 5.1e-12 46.5 0.1 8.3e-12 45.8 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 EKX46598.1 - 1.1e-05 25.8 0.0 1.7e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy PF03171.20 EKX46598.1 - 0.00067 20.1 0.0 0.0016 18.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 EKX46598.1 - 0.076 13.4 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase CH_2 PF06294.11 EKX46599.1 - 9.1e-26 89.8 0.0 1.7e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 EKX46599.1 - 5.1e-14 51.9 0.0 7.7e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.31 EKX46599.1 - 0.0069 16.5 0.3 0.011 15.9 0.3 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain UPF0184 PF03670.13 EKX46600.1 - 0.11 12.9 0.3 0.25 11.7 0.1 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) Slu7 PF11708.8 EKX46601.1 - 9.5e-87 291.1 19.0 9.5e-87 291.1 19.0 2.4 3 0 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor cwf18 PF08315.12 EKX46602.1 - 0.0029 18.3 1.5 0.0033 18.1 1.5 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor CENP-F_leu_zip PF10473.9 EKX46603.1 - 0.0022 18.1 23.9 0.012 15.7 4.3 3.0 1 1 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.6 EKX46603.1 - 0.025 13.2 12.3 0.037 12.7 12.3 1.3 1 0 0 1 1 1 0 AAA domain SWI-SNF_Ssr4 PF08549.10 EKX46603.1 - 0.044 12.4 9.1 0.062 11.9 9.1 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Fez1 PF06818.15 EKX46603.1 - 0.048 14.1 23.5 0.15 12.5 14.2 3.1 1 1 2 3 3 3 0 Fez1 DUF1043 PF06295.12 EKX46603.1 - 0.076 13.0 9.8 35 4.4 0.0 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) Sec34 PF04136.15 EKX46603.1 - 0.076 12.9 7.7 0.38 10.6 6.3 2.6 2 1 0 2 2 2 0 Sec34-like family Fib_alpha PF08702.10 EKX46603.1 - 0.18 12.0 18.6 0.54 10.4 14.7 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF5593 PF18007.1 EKX46603.1 - 0.22 12.2 0.8 17 6.2 0.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5593) Syntaxin-6_N PF09177.11 EKX46603.1 - 0.23 12.0 10.3 10 6.8 8.3 2.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Baculo_LEF-2 PF03041.14 EKX46603.1 - 0.34 10.5 7.7 0.099 12.3 0.7 2.2 1 1 0 2 2 2 0 lef-2 HMMR_N PF15905.5 EKX46603.1 - 0.36 10.2 26.7 0.43 10.0 25.6 1.7 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Cob_adeno_trans PF01923.18 EKX46603.1 - 0.41 10.8 9.3 2.9 8.0 0.0 3.0 1 1 0 2 2 2 0 Cobalamin adenosyltransferase ERM PF00769.19 EKX46603.1 - 0.55 10.0 29.0 0.17 11.7 11.1 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family BLOC1_2 PF10046.9 EKX46603.1 - 0.64 10.3 14.3 0.24 11.8 2.9 3.4 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Noelin-1 PF12308.8 EKX46603.1 - 0.89 9.6 9.4 0.12 12.4 2.4 2.8 3 0 0 3 3 3 0 Neurogenesis glycoprotein SlyX PF04102.12 EKX46603.1 - 1.3 9.7 9.9 2.1 9.0 0.1 4.2 2 1 2 4 4 4 0 SlyX DUF1664 PF07889.12 EKX46603.1 - 1.6 8.8 11.9 2.8 8.0 2.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF641 PF04859.12 EKX46603.1 - 2.6 8.4 21.3 6.9 7.0 5.3 3.4 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) AATF-Che1 PF13339.6 EKX46603.1 - 2.8 8.6 15.5 2.2e+02 2.5 15.5 3.1 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor NPV_P10 PF05531.12 EKX46603.1 - 3.8 8.0 7.2 60 4.2 5.7 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein USP8_interact PF08941.10 EKX46603.1 - 4.4 7.1 7.1 18 5.1 1.1 3.0 2 1 2 4 4 4 0 USP8 interacting DUF4618 PF15397.6 EKX46603.1 - 4.7 6.6 22.3 1.2 8.5 4.8 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) DUF948 PF06103.11 EKX46603.1 - 6 7.2 5.3 9.8 6.5 3.3 2.4 3 0 0 3 3 2 0 Bacterial protein of unknown function (DUF948) Lectin_N PF03954.14 EKX46603.1 - 6.1 6.6 7.9 23 4.8 0.4 2.7 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Spc7 PF08317.11 EKX46603.1 - 6.3 5.6 26.9 1.5 7.6 20.3 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein Phage_GPO PF05929.11 EKX46603.1 - 6.5 6.3 17.0 0.42 10.2 3.3 2.5 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase BRE1 PF08647.11 EKX46603.1 - 6.7 6.9 22.7 2.9e+02 1.6 20.5 3.3 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase UPF0242 PF06785.11 EKX46603.1 - 7.9 6.5 26.1 1.4 9.0 20.2 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Ribosomal_S6 PF01250.17 EKX46603.1 - 8.9 6.7 6.5 79 3.6 5.5 2.4 1 1 1 2 2 2 0 Ribosomal protein S6 APG6_N PF17675.1 EKX46603.1 - 9.4 6.8 29.4 4.5 7.8 5.8 2.9 2 1 1 3 3 3 0 Apg6 coiled-coil region TPR_1 PF00515.28 EKX46604.1 - 6e-16 57.5 3.5 7.3e-07 28.8 0.5 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX46604.1 - 1.4e-15 56.0 9.3 4.4e-06 26.4 0.1 3.4 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX46604.1 - 9.1e-13 47.7 0.8 2e-07 30.6 0.2 2.8 2 1 1 3 3 3 2 TPR repeat TPR_14 PF13428.6 EKX46604.1 - 1.6e-11 44.0 6.0 1.7e-05 25.2 0.4 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX46604.1 - 1e-09 37.8 0.5 0.00044 20.2 0.2 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX46604.1 - 5.5e-09 35.4 2.2 0.0011 18.9 0.3 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX46604.1 - 1.6e-08 34.9 0.6 0.00062 20.2 0.2 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX46604.1 - 1.8e-08 34.5 5.6 0.0018 18.5 1.9 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX46604.1 - 7.3e-08 32.9 13.3 0.00035 21.1 3.9 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX46604.1 - 3e-07 30.3 0.5 0.12 12.8 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX46604.1 - 5.4e-05 23.6 2.0 0.36 11.6 0.3 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX46604.1 - 0.00013 22.1 5.7 0.036 14.2 1.6 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_21 PF09976.9 EKX46604.1 - 0.00029 20.6 0.5 0.0011 18.8 0.2 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat-like domain MAS20 PF02064.15 EKX46604.1 - 0.00053 20.1 0.0 0.36 10.9 0.0 2.1 2 0 0 2 2 2 2 MAS20 protein import receptor TPR_15 PF13429.6 EKX46604.1 - 0.00058 19.2 1.5 0.092 11.9 0.1 2.2 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX46604.1 - 0.0022 17.8 2.8 0.18 11.7 0.5 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat NRBF2_MIT PF17169.4 EKX46604.1 - 0.0075 16.5 1.3 0.28 11.4 0.2 2.4 1 1 0 2 2 2 1 MIT domain of nuclear receptor-binding factor 2 DUF3856 PF12968.7 EKX46604.1 - 0.014 15.4 2.2 5.7 7.0 2.2 2.9 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) SHNi-TPR PF10516.9 EKX46604.1 - 0.028 13.9 0.5 2 7.9 0.1 2.5 2 0 0 2 2 2 0 SHNi-TPR MIT PF04212.18 EKX46604.1 - 0.069 13.2 2.5 0.14 12.2 0.8 2.1 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain SMG1 PF15785.5 EKX46604.1 - 0.073 11.4 0.4 0.23 9.8 0.2 1.7 1 1 1 2 2 2 0 Serine/threonine-protein kinase smg-1 BTAD PF03704.17 EKX46604.1 - 0.11 13.0 3.4 1 9.8 0.3 2.1 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_4 PF07721.14 EKX46604.1 - 0.98 10.2 8.6 8.2 7.4 0.4 3.4 3 2 0 3 3 3 0 Tetratricopeptide repeat RCC1 PF00415.18 EKX46605.1 - 8.3e-61 202.4 32.1 1.4e-14 54.4 1.0 6.1 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX46605.1 - 4.1e-32 109.3 40.2 6.6e-08 32.2 0.5 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Laminin_B PF00052.18 EKX46606.1 - 9.7e-08 32.0 0.0 9.7e-08 32.0 0.0 2.3 2 1 0 2 2 2 1 Laminin B (Domain IV) DUF4203 PF13886.6 EKX46607.1 - 3.2e-06 27.0 15.6 6.6e-06 25.9 15.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) SPC12 PF06645.13 EKX46607.1 - 0.21 11.7 7.2 0.091 12.9 2.9 2.6 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Asp_protease_2 PF13650.6 EKX46609.1 - 1e-12 48.5 3.6 1.6e-05 25.5 0.2 2.7 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 EKX46609.1 - 6.7e-12 45.8 0.7 2.7e-05 24.6 0.2 2.4 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease SAP PF02037.27 EKX46609.1 - 0.00014 21.5 0.2 0.00052 19.7 0.0 2.0 2 0 0 2 2 2 1 SAP domain RVP PF00077.20 EKX46609.1 - 0.17 12.2 0.0 9.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Retroviral aspartyl protease Sulf_transp PF04143.14 EKX46610.1 - 7.4e-06 25.7 39.6 0.0026 17.4 5.4 4.0 1 1 0 2 2 2 2 Sulphur transport HATPase_c_3 PF13589.6 EKX46611.1 - 2.2e-12 47.0 0.0 5.7e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF5576 PF17739.1 EKX46611.1 - 0.0076 16.4 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5576) Atg14 PF10186.9 EKX46611.1 - 3.8 6.5 10.0 1.7 7.7 2.1 2.4 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Peptidase_M16_M PF16187.5 EKX46612.1 - 3.9e-60 203.5 0.0 8.2e-60 202.5 0.0 1.6 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EKX46612.1 - 5.6e-37 127.0 0.1 2.3e-36 125.0 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EKX46612.1 - 3.6e-30 105.3 0.1 2.3e-18 66.9 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain Methyltrn_RNA_4 PF09936.9 EKX46612.1 - 0.052 13.4 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase ATP_bind_1 PF03029.17 EKX46613.1 - 6.5e-73 245.5 0.2 7.3e-73 245.3 0.2 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 EKX46613.1 - 5.2e-08 32.7 0.1 4.2e-07 29.7 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.19 EKX46613.1 - 0.0002 21.0 0.0 0.18 11.4 0.0 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 EKX46613.1 - 0.0039 16.7 0.0 0.037 13.5 0.0 2.4 3 0 0 3 3 3 1 Ferrous iron transport protein B NACHT PF05729.12 EKX46613.1 - 0.0041 17.0 0.0 0.0069 16.3 0.0 1.3 1 0 0 1 1 1 1 NACHT domain MeaB PF03308.16 EKX46613.1 - 0.0053 15.8 0.0 0.68 8.9 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 EKX46613.1 - 0.018 14.5 0.0 2.6 7.5 0.0 2.9 2 1 0 2 2 2 0 ADP-ribosylation factor family Ras PF00071.22 EKX46613.1 - 0.039 13.6 0.0 0.17 11.5 0.0 2.1 2 1 0 2 2 2 0 Ras family SRP54 PF00448.22 EKX46613.1 - 0.13 11.9 0.0 3 7.4 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Csm1_N PF18504.1 EKX46614.1 - 3.3 8.1 7.0 0.44 10.9 2.5 1.8 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF218 PF02698.17 EKX46615.1 - 4.4e-05 23.5 0.0 7.6e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 DUF218 domain CRAL_TRIO PF00650.20 EKX46616.1 - 1.5e-10 41.1 0.0 2.5e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EKX46616.1 - 0.00038 20.6 0.0 0.00085 19.5 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain 2OG-FeII_Oxy_4 PF13661.6 EKX46617.1 - 4.2e-15 56.2 0.1 8.4e-15 55.2 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EKX46617.1 - 1.5e-13 51.4 0.1 2.7e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LOR PF04525.12 EKX46617.1 - 0.037 13.6 0.1 0.062 12.9 0.1 1.4 1 0 0 1 1 1 0 LURP-one-related ATP19 PF11022.8 EKX46617.1 - 0.12 12.7 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 ATP synthase subunit K Cas9_PI PF16595.5 EKX46617.1 - 0.14 12.0 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 PAM-interacting domain of CRISPR-associated endonuclease Cas9 TPR_8 PF13181.6 EKX46619.1 - 0.29 11.5 4.3 1.6 9.2 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EKX46619.1 - 0.42 10.8 4.9 6.7 7.1 0.5 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Ion_trans PF00520.31 EKX46620.1 - 3.1e-121 403.2 88.9 5e-41 140.5 14.8 4.1 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 EKX46620.1 - 4.9e-08 32.1 14.3 1.7e-05 23.7 0.1 7.6 6 4 3 9 9 9 5 Polycystin cation channel Dynamin_N PF00350.23 EKX46621.1 - 1.4e-11 44.8 0.0 2.1e-05 24.6 0.0 2.2 1 1 1 2 2 2 2 Dynamin family MMR_HSR1 PF01926.23 EKX46621.1 - 2.6e-10 40.4 0.0 5.3e-10 39.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF5600 PF18150.1 EKX46621.1 - 3.8e-07 30.6 3.9 4.3e-07 30.5 2.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5600) RsgA_GTPase PF03193.16 EKX46621.1 - 0.00057 19.8 0.2 0.095 12.6 0.1 3.1 2 1 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 EKX46621.1 - 0.0063 16.0 0.3 0.47 10.0 0.1 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B Roc PF08477.13 EKX46621.1 - 0.025 14.8 0.0 0.41 10.9 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 EKX46621.1 - 0.072 13.3 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 EKX46621.1 - 0.19 11.2 0.1 4 6.9 0.1 2.7 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Septin PF00735.18 EKX46621.1 - 0.2 10.9 0.0 0.43 9.8 0.0 1.6 1 1 0 1 1 1 0 Septin FAD_binding_3 PF01494.19 EKX46622.1 - 3.9e-15 55.9 0.0 1.8e-08 34.0 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EKX46622.1 - 0.00045 20.4 0.0 0.00098 19.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EKX46622.1 - 0.00046 19.9 0.0 0.00071 19.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EKX46622.1 - 0.0066 15.7 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EKX46622.1 - 0.01 15.9 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding SE PF08491.10 EKX46622.1 - 0.027 13.5 0.0 0.089 11.8 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase Glu_dehyd_C PF16912.5 EKX46622.1 - 0.027 13.9 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Pyr_redox_2 PF07992.14 EKX46622.1 - 0.056 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EKX46622.1 - 0.2 11.7 0.1 0.93 9.5 0.0 2.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase HEAT PF02985.22 EKX46623.1 - 0.012 15.8 3.4 23 5.6 0.3 5.7 5 0 0 5 5 5 0 HEAT repeat PGAP1 PF07819.13 EKX46624.1 - 0.00013 21.7 0.3 0.00046 20.0 0.0 2.0 2 1 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 EKX46624.1 - 0.00021 20.9 0.0 0.0035 16.9 0.0 2.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EKX46624.1 - 0.0005 20.7 3.1 0.0015 19.1 3.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EKX46624.1 - 0.00059 19.6 0.0 0.037 13.7 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EKX46624.1 - 0.00086 18.6 0.1 0.0056 16.0 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Palm_thioest PF02089.15 EKX46624.1 - 0.0012 18.7 0.0 0.0014 18.6 0.0 1.3 1 1 0 1 1 1 1 Palmitoyl protein thioesterase Thioesterase PF00975.20 EKX46624.1 - 0.025 14.7 0.0 0.04 14.0 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF900 PF05990.12 EKX46624.1 - 0.063 12.8 0.0 0.063 12.8 0.0 2.1 2 1 1 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF900) DUF2235 PF09994.9 EKX46624.1 - 0.076 12.4 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) O-FucT PF10250.9 EKX46625.1 - 5.6e-05 23.0 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase ODV-E18 PF10717.9 EKX46625.1 - 0.041 13.7 0.6 0.11 12.4 0.6 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 dsDNA_bind PF01984.20 EKX46625.1 - 0.95 9.8 7.4 1.8 8.9 7.4 1.4 1 0 0 1 1 1 0 Double-stranded DNA-binding domain Orf78 PF06024.12 EKX46625.1 - 1.2 9.5 3.4 5.8 7.3 0.1 2.2 2 0 0 2 2 2 0 Orf78 (ac78) DUF4245 PF14030.6 EKX46625.1 - 1.6 8.7 6.4 45 4.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4245) SP_C-Propep PF08999.10 EKX46625.1 - 2.6 7.9 7.7 6.3 6.6 7.7 1.6 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide CAF1C_H4-bd PF12265.8 EKX46626.1 - 3.9e-11 43.0 0.1 1.3e-10 41.4 0.1 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EKX46626.1 - 9.9e-11 42.0 20.0 0.021 15.7 0.2 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF262 PF03235.14 EKX46627.1 - 0.018 15.2 0.4 0.018 15.2 0.4 2.4 3 0 0 3 3 3 0 Protein of unknown function DUF262 RRM_1 PF00076.22 EKX46627.1 - 0.13 12.2 0.0 0.33 10.8 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET PF00856.28 EKX46628.1 - 2e-11 44.6 0.0 6.9e-11 42.8 0.0 1.9 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 EKX46628.1 - 1.4e-09 38.7 7.5 3.9e-08 34.1 0.2 3.0 3 0 0 3 3 3 2 Rubisco LSMT substrate-binding Nop14 PF04147.12 EKX46628.1 - 0.0091 14.3 6.1 0.012 13.9 6.1 1.1 1 0 0 1 1 1 1 Nop14-like family RNA_pol_3_Rpc31 PF11705.8 EKX46628.1 - 0.012 15.9 11.7 0.025 14.8 11.7 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Ribosomal_60s PF00428.19 EKX46628.1 - 0.024 15.2 9.9 0.024 15.2 9.9 2.6 3 0 0 3 3 2 0 60s Acidic ribosomal protein SpoIIIAH PF12685.7 EKX46628.1 - 0.025 14.4 2.0 0.038 13.8 2.0 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein FYDLN_acid PF09538.10 EKX46628.1 - 0.054 14.2 5.9 0.14 12.8 5.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Myc_N PF01056.18 EKX46628.1 - 0.067 13.1 4.2 0.11 12.4 4.2 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Pox_Ag35 PF03286.14 EKX46628.1 - 0.071 12.9 4.2 0.13 12.0 4.2 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4820 PF16091.5 EKX46628.1 - 0.18 11.2 2.8 0.58 9.5 2.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) RPN2_C PF18004.1 EKX46628.1 - 0.2 11.6 10.0 0.44 10.5 10.0 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Afi1 PF07792.12 EKX46628.1 - 0.49 10.9 4.5 1 9.8 4.5 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking FAM176 PF14851.6 EKX46628.1 - 0.56 9.9 9.1 0.72 9.5 7.6 1.9 2 0 0 2 2 2 0 FAM176 family MAP17 PF15807.5 EKX46628.1 - 0.62 10.3 4.4 1.7 8.9 4.4 1.7 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 TRAP_alpha PF03896.16 EKX46628.1 - 0.8 8.9 3.9 1.6 7.9 3.9 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF3306 PF11748.8 EKX46628.1 - 0.87 10.5 8.3 2.4 9.0 8.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) MRNIP PF15749.5 EKX46628.1 - 0.89 10.3 8.6 2.2 9.0 8.6 1.7 1 0 0 1 1 1 0 MRN-interacting protein DUF4746 PF15928.5 EKX46628.1 - 1.4 8.3 11.7 3.3 7.0 11.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CENP-B_dimeris PF09026.10 EKX46628.1 - 1.5 9.3 8.5 3.1 8.2 8.5 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3381 PF11861.8 EKX46628.1 - 1.6 8.5 14.9 3.8 7.3 14.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) PBP1_TM PF14812.6 EKX46628.1 - 2 8.9 5.9 6.6 7.2 5.9 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cytomega_UL84 PF06284.11 EKX46628.1 - 2.1 6.7 3.6 3 6.2 3.6 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein PPL5 PF18168.1 EKX46628.1 - 2.6 7.3 4.7 1.7 7.9 2.5 1.7 2 0 0 2 2 2 0 Prim-pol family 5 Adeno_terminal PF02459.15 EKX46628.1 - 3.5 5.9 5.2 5.4 5.3 5.2 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein RRN3 PF05327.11 EKX46628.1 - 6.1 5.3 6.4 9.5 4.6 6.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop53 PF07767.11 EKX46628.1 - 6.7 6.0 18.7 12 5.2 18.7 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Vfa1 PF08432.10 EKX46628.1 - 8 6.8 9.8 17 5.7 9.8 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 MscS_TM PF12794.7 EKX46628.1 - 9.4 5.0 6.6 15 4.4 6.6 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 RNB PF00773.19 EKX46629.1 - 1.2e-33 116.9 0.1 2.2e-30 106.1 0.1 2.2 1 1 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 EKX46629.1 - 6.3e-20 71.0 0.0 1.2e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_S1 PF17215.3 EKX46629.1 - 1.3e-12 47.5 0.0 3.2e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 S1 domain PIN_4 PF13638.6 EKX46629.1 - 5.6e-12 46.1 0.9 1.4e-11 44.8 0.0 2.1 2 0 0 2 2 2 1 PIN domain Rrp44_CSD1 PF17216.3 EKX46629.1 - 1.8e-07 31.0 0.1 1.9e-06 27.7 0.1 2.7 3 1 1 4 4 4 1 Rrp44-like cold shock domain CSD2 PF17876.1 EKX46629.1 - 0.00016 21.8 0.6 0.032 14.4 0.0 3.2 3 0 0 3 3 3 1 Cold shock domain SPRY PF00622.28 EKX46631.1 - 9.4e-06 25.7 0.0 0.089 12.9 0.0 2.4 2 0 0 2 2 2 2 SPRY domain WGG PF10273.9 EKX46631.1 - 0.052 14.2 0.5 24 5.7 0.1 3.3 2 0 0 2 2 2 0 Pre-rRNA-processing protein TSR2 SelB-wing_1 PF09105.10 EKX46631.1 - 0.28 11.2 3.6 21 5.1 0.3 3.2 2 0 0 2 2 2 0 Elongation factor SelB, winged helix DUF2774 PF11242.8 EKX46631.1 - 0.71 10.1 8.1 36 4.7 0.2 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2774) STAG PF08514.11 EKX46632.1 - 1.1e-06 28.5 3.5 2.7e-06 27.2 0.1 2.6 2 0 0 2 2 2 1 STAG domain DUF2868 PF11067.8 EKX46632.1 - 0.0016 18.0 0.1 0.003 17.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2868) GRIM-19 PF06212.12 EKX46632.1 - 0.32 10.9 1.8 1.1 9.2 1.8 1.9 1 0 0 1 1 1 0 GRIM-19 protein FmiP_Thoc5 PF09766.9 EKX46632.1 - 0.41 9.9 6.2 0.076 12.3 0.4 2.2 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 HEAT_EZ PF13513.6 EKX46632.1 - 0.94 10.1 3.8 25 5.5 0.1 3.8 4 0 0 4 4 4 0 HEAT-like repeat DUF3446 PF11928.8 EKX46632.1 - 3.1 8.2 11.8 0.071 13.4 3.5 2.5 3 0 0 3 3 3 0 Early growth response N-terminal domain DUF1538 PF07556.11 EKX46633.1 - 5.9e-105 349.2 38.5 4.1e-55 186.4 18.6 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1538) Ank_2 PF12796.7 EKX46635.1 - 6.4e-05 23.5 0.0 7.1e-05 23.3 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX46635.1 - 0.00052 20.2 0.0 0.0031 17.8 0.1 1.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX46635.1 - 0.0006 20.3 0.0 0.028 15.0 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX46635.1 - 0.1 13.2 0.0 37 5.3 0.0 2.9 3 0 0 3 3 3 0 Ankyrin repeat ptaRNA1_toxin PF12703.7 EKX46636.1 - 0.032 14.3 0.3 0.56 10.3 0.1 2.5 2 0 0 2 2 2 0 Toxin of toxin-antitoxin type 1 system WD40 PF00400.32 EKX46637.1 - 1.8e-75 246.9 55.0 8.7e-10 39.1 1.2 13.8 14 0 0 14 14 14 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX46637.1 - 2.7e-38 130.1 22.0 2.4e-09 37.4 0.7 11.7 3 2 10 13 13 13 10 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 EKX46637.1 - 2.6e-14 52.3 0.0 0.16 12.0 0.0 7.7 8 0 0 8 8 7 3 PQQ enzyme repeat PQQ_2 PF13360.6 EKX46637.1 - 3.4e-11 43.2 28.8 4.5e-06 26.4 7.4 4.1 1 1 3 4 4 4 3 PQQ-like domain PQQ_3 PF13570.6 EKX46637.1 - 4.7e-10 39.6 10.8 4 8.0 0.1 8.0 7 0 0 7 7 6 3 PQQ-like domain eIF2A PF08662.11 EKX46637.1 - 5.5e-08 32.9 1.1 9.3e-05 22.4 0.1 3.9 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.6 EKX46637.1 - 1.3e-07 31.6 6.0 0.038 14.0 0.0 6.2 3 2 2 7 7 7 3 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 EKX46637.1 - 8.2e-07 28.3 2.2 0.19 10.7 0.0 5.9 1 1 5 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4921 PF16268.5 EKX46637.1 - 1.2e-05 24.4 6.0 1.4 7.6 0.1 5.1 5 0 0 5 5 5 2 Domain of unknown function (DUF4921) PD40 PF07676.12 EKX46637.1 - 7.4e-05 22.6 1.2 19 5.4 0.0 5.8 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 EKX46637.1 - 0.00018 20.7 3.0 1.6 7.7 0.0 4.3 2 1 1 4 4 4 1 Coatomer WD associated region Nbas_N PF15492.6 EKX46637.1 - 0.0019 17.6 21.2 0.51 9.6 0.0 7.6 2 2 5 8 8 8 2 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 EKX46637.1 - 0.0022 17.4 0.0 9 5.5 0.0 4.6 4 1 1 5 5 5 1 WD40-like domain PHTB1_N PF14727.6 EKX46637.1 - 0.0025 17.2 0.7 19 4.5 0.0 4.9 1 1 4 5 5 5 0 PTHB1 N-terminus CBM_20 PF00686.19 EKX46637.1 - 0.0033 17.3 5.0 1.9 8.4 0.0 4.7 2 1 3 5 5 4 1 Starch binding domain DUF5640 PF18692.1 EKX46637.1 - 0.044 13.8 0.0 41 4.3 0.0 4.1 5 0 0 5 5 4 0 Family of unknown function (DUF5640) DTW PF03942.15 EKX46637.1 - 0.11 12.1 0.4 0.19 11.4 0.4 1.3 1 0 0 1 1 1 0 DTW domain RunxI PF08504.11 EKX46637.1 - 0.14 12.9 9.9 6.6 7.5 0.6 5.2 4 2 1 5 5 5 0 Runx inhibition domain IKI3 PF04762.12 EKX46637.1 - 0.37 8.7 10.5 2.7 5.9 5.4 3.4 1 1 1 2 2 2 0 IKI3 family DUF1057 PF06342.12 EKX46637.1 - 8.4 5.3 5.9 35 3.3 0.0 3.7 6 0 0 6 6 6 0 Alpha/beta hydrolase of unknown function (DUF1057) Pkinase_Tyr PF07714.17 EKX46638.1 - 2.9e-17 62.8 0.0 1e-12 47.9 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 EKX46638.1 - 5.6e-16 58.7 0.0 4.2e-13 49.3 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Kdo PF06293.14 EKX46638.1 - 9.4e-05 21.9 0.0 0.00011 21.7 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EKX46638.1 - 0.0078 15.6 0.0 0.012 15.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EKX46638.1 - 0.023 14.6 0.0 0.028 14.3 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX46638.1 - 0.12 11.1 0.0 0.14 10.9 0.0 1.0 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 EKX46639.1 - 8.2e-28 97.5 0.0 9.2e-28 97.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX46639.1 - 3.6e-17 62.5 0.0 4.2e-17 62.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX46639.1 - 1.1e-07 31.0 0.1 1.3e-07 30.8 0.1 1.0 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EKX46639.1 - 0.0029 17.2 0.0 0.0043 16.6 0.0 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.22 EKX46639.1 - 0.0047 16.5 0.1 0.0078 15.8 0.1 1.4 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 EKX46639.1 - 0.0055 16.1 0.9 0.0069 15.8 0.9 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX46639.1 - 0.012 15.6 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PARP PF00644.20 EKX46640.1 - 3.3e-24 85.6 0.0 1.2e-23 83.7 0.0 1.7 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain ABC_tran PF00005.27 EKX46641.1 - 1.1e-08 35.7 0.1 2e-08 34.9 0.1 1.4 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EKX46641.1 - 1.6e-07 31.0 0.0 1.9e-07 30.8 0.0 1.0 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain CcmH PF03918.14 EKX46642.1 - 0.062 12.6 0.4 0.31 10.3 0.0 2.2 2 0 0 2 2 2 0 Cytochrome C biogenesis protein PDZ_6 PF17820.1 EKX46645.1 - 9.5e-10 38.2 0.6 1.7e-09 37.4 0.6 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX46645.1 - 1.5e-08 34.9 0.2 2.7e-08 34.0 0.2 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX46645.1 - 7.6e-08 32.6 0.1 1.6e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Hydrolase_4 PF12146.8 EKX46645.1 - 0.01 15.1 0.1 0.35 10.1 0.1 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydro_lipase PF04083.16 EKX46646.1 - 2.2e-11 43.1 0.0 4.9e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EKX46646.1 - 0.0026 17.5 0.0 0.0072 16.0 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold PDZ PF00595.24 EKX46647.1 - 3.1e-13 49.9 0.6 1.9e-06 28.1 0.1 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EKX46647.1 - 2.5e-11 43.2 0.4 6.3e-08 32.3 0.2 2.8 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX46647.1 - 2.7e-11 43.6 0.2 4.1e-05 23.8 0.1 2.5 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 EKX46647.1 - 0.00019 21.4 0.1 0.0031 17.4 0.2 2.6 2 0 0 2 2 2 1 Tricorn protease PDZ domain WWE PF02825.20 EKX46647.1 - 0.00073 20.1 0.0 0.0031 18.0 0.0 2.1 1 0 0 1 1 1 1 WWE domain YtxH PF12732.7 EKX46647.1 - 0.083 13.4 1.4 0.24 11.9 1.4 1.7 1 0 0 1 1 1 0 YtxH-like protein HALZ PF02183.18 EKX46647.1 - 2 8.7 8.4 0.24 11.6 1.4 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Cnn_1N PF07989.11 EKX46647.1 - 2.3 8.5 6.8 12 6.1 1.4 2.8 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 UBA_4 PF14555.6 EKX46648.1 - 0.026 14.3 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain PP1_inhibitor PF05361.12 EKX46648.1 - 0.15 12.1 0.1 0.34 10.9 0.0 1.6 2 0 0 2 2 2 0 PKC-activated protein phosphatase-1 inhibitor Glyco_transf_10 PF00852.19 EKX46649.1 - 0.0034 17.1 0.2 0.0063 16.2 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term DUF5330 PF17264.2 EKX46649.1 - 0.024 14.6 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5330) XG_FTase PF03254.13 EKX46650.1 - 0.00021 20.1 0.0 0.00035 19.3 0.0 1.2 1 0 0 1 1 1 1 Xyloglucan fucosyltransferase dCMP_cyt_deam_1 PF00383.23 EKX46651.1 - 9e-24 83.3 1.3 1.5e-23 82.6 1.3 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EKX46651.1 - 1.9e-21 76.2 0.3 2.3e-21 76.0 0.3 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 EKX46651.1 - 0.003 17.6 0.0 0.005 16.9 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 EKX46651.1 - 0.0031 17.6 0.0 0.0053 16.9 0.0 1.3 1 0 0 1 1 1 1 APOBEC3 Bd3614-deam PF14439.6 EKX46651.1 - 0.0066 16.5 4.3 0.033 14.3 4.3 2.0 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC2 PF18772.1 EKX46651.1 - 0.0079 16.3 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 APOBEC2 NAD1 PF18778.1 EKX46651.1 - 0.0079 16.3 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 NAD2 PF18782.1 EKX46651.1 - 0.034 14.3 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 APOBEC_N PF08210.11 EKX46651.1 - 0.05 13.5 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 APOBEC-like N-terminal domain APOBEC4_like PF18774.1 EKX46651.1 - 0.09 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase EF-hand_6 PF13405.6 EKX46652.1 - 0.002 17.9 0.0 0.0098 15.8 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 EKX46652.1 - 0.0026 18.2 0.0 0.15 12.5 0.0 2.7 2 1 0 2 2 2 1 EF-hand domain pair RIIa PF02197.17 EKX46652.1 - 0.003 17.2 0.0 0.01 15.5 0.0 1.8 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit EF-hand_1 PF00036.32 EKX46652.1 - 0.0054 16.2 0.1 0.82 9.4 0.0 3.2 3 0 0 3 3 3 1 EF hand Dpy-30 PF05186.13 EKX46652.1 - 0.0072 16.0 0.2 0.017 14.8 0.2 1.7 1 1 0 1 1 1 1 Dpy-30 motif EF-hand_9 PF14658.6 EKX46652.1 - 0.014 15.7 0.0 0.043 14.1 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain EF-hand_4 PF12763.7 EKX46652.1 - 0.054 13.5 0.4 0.21 11.5 0.0 2.1 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Globin PF00042.22 EKX46654.1 - 4.4e-08 33.6 0.0 6.3e-07 29.9 0.0 2.3 2 1 0 2 2 2 1 Globin SRCR PF00530.18 EKX46655.1 - 2.9e-25 88.7 6.8 3.2e-25 88.5 6.8 1.0 1 0 0 1 1 1 1 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 EKX46655.1 - 8.5e-05 23.0 2.2 0.00012 22.6 2.2 1.5 1 1 0 1 1 1 1 Scavenger receptor cysteine-rich domain DUF3363 PF11843.8 EKX46655.1 - 0.24 10.3 0.0 0.24 10.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3363) WD40 PF00400.32 EKX46656.1 - 9e-60 197.2 27.5 6.9e-08 33.0 0.1 10.2 11 0 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX46656.1 - 2e-23 82.5 3.0 0.00071 19.8 0.1 8.2 1 1 7 8 8 8 8 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EKX46656.1 - 0.0082 14.8 4.5 2.3 6.8 0.0 4.2 3 1 1 5 5 5 1 Nucleoporin Nup120/160 Gmad1 PF10647.9 EKX46656.1 - 0.053 13.3 6.7 1.2 8.8 0.3 3.3 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain Ge1_WD40 PF16529.5 EKX46656.1 - 0.074 12.0 2.9 7.9 5.3 0.2 4.3 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1652 PF07865.11 EKX46656.1 - 0.093 12.6 0.1 0.95 9.3 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1652) NQRA PF05896.11 EKX46656.1 - 0.13 11.6 0.0 12 5.2 0.0 2.1 2 0 0 2 2 2 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) NHL PF01436.21 EKX46656.1 - 0.15 12.2 0.3 8.4 6.6 0.0 3.8 3 0 0 3 3 3 0 NHL repeat Ank_2 PF12796.7 EKX46657.1 - 0.00035 21.1 0.0 0.001 19.6 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX46657.1 - 0.0036 17.6 0.0 0.2 12.0 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX46657.1 - 0.0041 17.7 0.0 0.84 10.3 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX46657.1 - 0.0063 16.9 0.3 0.022 15.3 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat EF-hand_8 PF13833.6 EKX46657.1 - 0.017 15.0 0.6 0.069 13.0 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair Ank PF00023.30 EKX46657.1 - 0.11 13.0 0.0 15 6.2 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat EF-hand_6 PF13405.6 EKX46657.1 - 0.11 12.4 0.0 0.85 9.7 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain RepB PF07506.11 EKX46657.1 - 0.18 11.9 3.8 0.49 10.5 0.1 2.4 2 0 0 2 2 2 0 RepB plasmid partitioning protein KRTAP PF11759.8 EKX46657.1 - 4.9 7.8 19.4 14 6.4 19.4 1.7 1 0 0 1 1 1 0 Keratin-associated matrix Tim44 PF04280.15 EKX46658.1 - 2.8e-06 27.5 0.6 7.2e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 Tim44-like domain DUF4407 PF14362.6 EKX46658.1 - 0.014 14.7 9.2 0.022 14.1 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fe_bilin_red PF05996.12 EKX46658.1 - 0.062 13.0 0.8 0.12 12.1 0.8 1.5 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase YkyA PF10368.9 EKX46658.1 - 0.5 10.0 12.1 1.1 8.9 8.5 2.3 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein DUF4240 PF14024.6 EKX46658.1 - 0.51 10.5 2.9 1.5 9.0 2.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4240) HWE_HK PF07536.14 EKX46658.1 - 1 10.1 7.9 5.8 7.7 1.6 2.8 3 0 0 3 3 3 0 HWE histidine kinase Ntox28 PF15605.6 EKX46658.1 - 1.1 9.6 6.3 0.77 10.0 0.1 2.8 3 0 0 3 3 3 0 Bacterial toxin 28 DivIVA PF05103.13 EKX46658.1 - 3.9 7.6 13.0 14 5.8 7.9 2.6 2 0 0 2 2 2 0 DivIVA protein F-box PF00646.33 EKX46659.1 - 4.4e-05 23.2 1.3 4.4e-05 23.2 1.3 1.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EKX46659.1 - 0.00029 20.7 1.6 0.00029 20.7 1.6 1.7 2 0 0 2 2 2 1 F-box-like DUF3450 PF11932.8 EKX46660.1 - 0.0077 15.6 6.4 0.051 12.9 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) Cep57_CLD_2 PF14197.6 EKX46660.1 - 0.014 15.5 3.0 0.014 15.5 3.0 4.0 5 1 0 5 5 5 0 Centrosome localisation domain of PPC89 DUF4407 PF14362.6 EKX46660.1 - 0.18 11.1 10.2 0.26 10.6 9.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) RBD-FIP PF09457.10 EKX46660.1 - 0.26 11.2 2.2 1.3 9.0 2.2 2.3 1 0 0 1 1 1 0 FIP domain Sec8_exocyst PF04048.14 EKX46660.1 - 0.3 11.0 3.6 2.8 7.8 0.4 2.5 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain ADIP PF11559.8 EKX46660.1 - 0.47 10.5 13.7 0.94 9.6 3.1 2.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 EKX46660.1 - 0.49 10.4 4.2 4.5 7.3 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 EKX46660.1 - 0.62 10.2 22.5 0.3 11.3 15.0 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Atg14 PF10186.9 EKX46660.1 - 4.6 6.2 15.9 11 5.0 12.4 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sipho_Gp157 PF05565.11 EKX46660.1 - 8.4 6.4 13.7 0.23 11.5 5.4 2.4 1 1 0 2 2 2 0 Siphovirus Gp157 mRNA_triPase PF02940.15 EKX46661.1 - 1.7e-18 67.2 0.0 1e-16 61.4 0.0 2.3 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain mRNA_cap_enzyme PF01331.19 EKX46661.1 - 1.6e-10 41.1 0.0 4.6e-10 39.6 0.0 1.8 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EKX46661.1 - 0.00076 20.1 0.5 0.0045 17.6 0.0 2.5 2 1 0 2 2 2 1 mRNA capping enzyme, C-terminal domain Fer4_11 PF13247.6 EKX46661.1 - 0.11 12.7 0.3 0.37 10.9 0.1 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain RTP801_C PF07809.11 EKX46661.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 RTP801 C-terminal region LEA_4 PF02987.16 EKX46661.1 - 0.16 12.1 0.1 0.16 12.1 0.1 2.3 2 0 0 2 2 2 0 Late embryogenesis abundant protein Na_H_Exchanger PF00999.21 EKX46662.1 - 2.6e-14 52.8 45.8 4.1e-14 52.2 45.8 1.3 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Mid2 PF04478.12 EKX46662.1 - 0.32 10.8 3.3 0.61 9.9 3.3 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor PetG PF02529.15 EKX46662.1 - 5.7 6.9 7.6 18 5.3 0.3 3.3 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 DUF3246 PF11596.8 EKX46663.1 - 0.08 12.4 0.6 0.13 11.6 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) H_PPase PF03030.16 EKX46666.1 - 5.5e-222 739.0 36.5 2e-203 677.6 29.4 2.0 2 0 0 2 2 2 2 Inorganic H+ pyrophosphatase DUF4281 PF14108.6 EKX46667.1 - 5.6e-29 101.1 5.5 6.3e-29 100.9 5.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) PDZ_6 PF17820.1 EKX46668.1 - 1.2e-05 25.1 0.0 2.7e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX46668.1 - 6e-05 23.3 0.0 0.00028 21.2 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX46668.1 - 0.0027 18.0 0.1 0.01 16.1 0.0 2.0 2 0 0 2 2 2 1 PDZ domain Tricorn_PDZ PF14685.6 EKX46668.1 - 0.046 13.7 0.0 0.19 11.7 0.0 2.1 1 0 0 1 1 1 0 Tricorn protease PDZ domain RecG_N PF17190.4 EKX46668.1 - 0.24 12.1 1.9 0.69 10.7 1.9 1.8 1 0 0 1 1 1 0 RecG N-terminal helical domain Glyco_transf_17 PF04724.13 EKX46669.1 - 2.5e-20 72.8 0.1 7.8e-10 38.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 17 PDZ_6 PF17820.1 EKX46670.1 - 5.7e-09 35.7 0.0 9.6e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PH PF00169.29 EKX46670.1 - 1.9e-07 31.5 0.1 3e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 PH domain PDZ PF00595.24 EKX46670.1 - 6.2e-07 29.7 0.6 1e-06 28.9 0.6 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX46670.1 - 2.2e-05 24.7 0.1 3.9e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX46670.1 - 0.00088 19.2 0.1 0.0025 17.8 0.0 1.7 1 1 1 2 2 2 1 Tricorn protease PDZ domain PRAS PF15798.5 EKX46674.1 - 0.018 15.7 0.2 0.032 14.8 0.2 1.5 1 1 0 1 1 1 0 Proline-rich AKT1 substrate 1 DEAD PF00270.29 EKX46676.1 - 3.3e-41 141.0 0.0 1e-40 139.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX46676.1 - 8.7e-27 93.7 0.0 2.2e-26 92.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX46676.1 - 1.2e-05 25.3 0.0 3.2e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Mucin PF01456.17 EKX46676.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Peptidase_S41 PF03572.18 EKX46677.1 - 9e-29 100.2 0.0 2.4e-28 98.8 0.0 1.7 2 0 0 2 2 2 1 Peptidase family S41 PDZ_2 PF13180.6 EKX46677.1 - 5.9e-13 48.9 0.1 1.5e-12 47.6 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX46677.1 - 6.8e-10 38.6 4.4 6e-09 35.6 0.1 4.1 5 0 0 5 5 5 1 PDZ domain PDZ PF00595.24 EKX46677.1 - 5.3e-07 29.9 0.0 1.4e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX46677.1 - 0.00076 19.4 0.2 0.0022 17.9 0.1 1.9 2 0 0 2 2 2 1 Tricorn protease PDZ domain DNA_photolyase PF00875.18 EKX46678.1 - 4.1e-20 72.4 0.0 2.8e-19 69.7 0.0 2.2 1 1 1 2 2 2 1 DNA photolyase Med26 PF08711.11 EKX46678.1 - 0.045 13.8 0.4 0.11 12.6 0.4 1.7 1 0 0 1 1 1 0 TFIIS helical bundle-like domain DUF2458 PF10454.9 EKX46678.1 - 0.1 12.3 1.6 0.23 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) BBP1_C PF15272.6 EKX46678.1 - 0.21 11.4 1.4 0.25 11.2 0.1 1.7 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal RabGAP-TBC PF00566.18 EKX46679.1 - 3.6e-54 183.7 3.8 4.6e-54 183.3 3.8 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RAP1 PF07218.11 EKX46679.1 - 0.26 9.5 16.8 0.39 8.9 16.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Secretin_N_2 PF07655.13 EKX46679.1 - 0.34 11.5 17.5 0.84 10.2 17.5 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Jnk-SapK_ap_N PF09744.9 EKX46679.1 - 0.5 10.6 2.8 17 5.6 1.6 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 CCDC24 PF15669.5 EKX46679.1 - 1.3 8.9 10.3 2.3 8.0 10.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Apt1 PF10351.9 EKX46679.1 - 1.7 7.4 10.1 2.9 6.6 10.1 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Herpes_pp85 PF04637.12 EKX46679.1 - 2.6 6.3 13.2 4.4 5.6 13.2 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Macoilin PF09726.9 EKX46679.1 - 5.3 5.5 14.3 9.4 4.7 14.3 1.3 1 0 0 1 1 1 0 Macoilin family DUF2024 PF09630.10 EKX46680.1 - 1.1e-06 28.4 9.2 20 5.1 0.0 6.2 1 1 4 6 6 6 6 Domain of unknown function (DUF2024) Porphobil_deam PF01379.20 EKX46680.1 - 0.00082 18.9 3.0 3.7 7.0 0.1 3.4 1 1 2 3 3 3 3 Porphobilinogen deaminase, dipyromethane cofactor binding domain PrgU PF09627.10 EKX46680.1 - 0.014 15.4 0.0 37 4.3 0.0 3.7 1 1 3 4 4 4 0 PrgU-like protein GDWWSH PF15667.5 EKX46680.1 - 0.86 9.0 12.3 2.9 7.2 0.6 3.3 1 1 2 3 3 3 0 Protein of unknown function with motif GDWWSH RPAP1_C PF08620.10 EKX46681.1 - 1.8e-25 88.9 0.0 4.6e-25 87.5 0.0 1.8 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 EKX46681.1 - 1.7e-06 27.6 6.2 1.7e-06 27.6 6.2 3.3 3 0 0 3 3 3 1 RPAP1-like, N-terminal Ank_2 PF12796.7 EKX46683.1 - 5.4e-13 49.3 0.0 1.1e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX46683.1 - 1.7e-11 44.4 0.0 4.1e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX46683.1 - 1.1e-10 41.6 0.0 0.00041 20.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX46683.1 - 6.5e-10 39.0 0.0 0.00031 21.0 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat WW PF00397.26 EKX46683.1 - 2.7e-08 33.8 0.0 4.8e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 WW domain Ank_3 PF13606.6 EKX46683.1 - 3.7e-08 33.0 0.0 0.0077 16.7 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Cadherin_C PF01049.17 EKX46683.1 - 0.091 13.1 0.8 1.9 8.8 1.0 2.5 2 0 0 2 2 2 0 Cadherin cytoplasmic region Vir_act_alpha_C PF10400.9 EKX46683.1 - 0.63 10.8 3.9 0.39 11.4 0.3 2.2 2 0 0 2 2 2 0 Virulence activator alpha C-term DUF3054 PF11255.8 EKX46684.1 - 4e-17 62.7 3.7 4.9e-17 62.4 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3054) DPM3 PF08285.11 EKX46684.1 - 0.013 15.7 0.9 0.053 13.7 0.9 2.0 1 1 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) EF-hand_1 PF00036.32 EKX46686.1 - 3e-28 95.2 39.6 1.3e-05 24.4 0.0 11.4 13 0 0 13 13 13 8 EF hand EF-hand_6 PF13405.6 EKX46686.1 - 5.7e-25 85.1 34.1 0.0057 16.5 0.0 12.9 13 0 0 13 13 13 7 EF-hand domain EF-hand_7 PF13499.6 EKX46686.1 - 1.5e-23 83.0 35.9 4.4e-05 23.9 2.0 10.2 7 4 5 12 12 12 10 EF-hand domain pair EF-hand_5 PF13202.6 EKX46686.1 - 8.6e-21 72.5 26.1 0.00088 18.7 0.1 8.1 7 0 0 7 7 7 5 EF hand EF-hand_8 PF13833.6 EKX46686.1 - 6.6e-20 70.7 28.6 0.0027 17.5 0.3 9.8 9 2 2 11 11 11 6 EF-hand domain pair EF-hand_11 PF08976.11 EKX46686.1 - 1.2e-06 29.4 1.1 3.5e-05 24.6 0.0 3.6 4 0 0 4 4 3 1 EF-hand domain HU-CCDC81_euk_2 PF18289.1 EKX46686.1 - 2.2e-06 27.7 0.0 2.5e-05 24.3 0.0 2.8 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 2 SPARC_Ca_bdg PF10591.9 EKX46686.1 - 0.00088 19.6 8.8 9.5 6.6 0.2 6.5 6 1 1 7 7 6 1 Secreted protein acidic and rich in cysteine Ca binding region Bac_DNA_binding PF00216.21 EKX46686.1 - 0.0077 16.4 0.6 2 8.7 0.0 3.8 3 0 0 3 3 3 1 Bacterial DNA-binding protein EF-hand_4 PF12763.7 EKX46686.1 - 0.015 15.3 13.9 0.5 10.3 0.1 6.3 7 0 0 7 7 7 0 Cytoskeletal-regulatory complex EF hand HU-CCDC81_euk_1 PF14908.6 EKX46686.1 - 0.047 13.8 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 CCDC81 eukaryotic HU domain 1 EF-hand_9 PF14658.6 EKX46686.1 - 0.07 13.5 0.1 3.8 7.9 0.0 3.7 4 0 0 4 4 4 0 EF-hand domain Dockerin_1 PF00404.18 EKX46686.1 - 0.072 13.3 6.4 3.3 8.0 0.0 4.8 5 1 0 5 5 5 0 Dockerin type I domain DUF1456 PF07308.13 EKX46686.1 - 0.19 12.1 4.9 31 5.0 0.0 5.7 7 0 0 7 7 7 0 Protein of unknown function (DUF1456) EF-hand_10 PF14788.6 EKX46686.1 - 0.2 11.6 2.8 4.5 7.2 0.0 4.6 5 0 0 5 5 5 0 EF hand Tn7_Tnp_TnsA_C PF08721.11 EKX46686.1 - 0.29 11.8 2.2 32 5.3 0.3 4.7 4 0 0 4 4 3 0 TnsA endonuclease C terminal MitMem_reg PF13012.6 EKX46689.1 - 8.1e-20 71.3 0.4 1.2e-19 70.7 0.4 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EKX46689.1 - 2.3e-17 63.1 0.0 4.4e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Acyl_transf_3 PF01757.22 EKX46690.1 - 7e-05 22.1 41.7 0.00015 21.0 41.7 1.6 1 1 0 1 1 1 1 Acyltransferase family DUF1965 PF09248.10 EKX46691.1 - 0.029 14.1 1.1 0.068 13.0 1.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1965) WW PF00397.26 EKX46692.1 - 0.00013 22.0 1.9 0.00031 20.8 1.9 1.7 1 0 0 1 1 1 1 WW domain DUF1180 PF06679.12 EKX46692.1 - 0.027 14.9 7.3 0.046 14.1 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) FAM176 PF14851.6 EKX46692.1 - 0.078 12.6 1.2 0.21 11.2 1.2 1.7 1 0 0 1 1 1 0 FAM176 family Laminin_EGF PF00053.24 EKX46692.1 - 0.28 11.4 45.8 0.12 12.6 15.1 4.0 3 0 0 3 3 3 0 Laminin EGF domain Ufd2P_core PF10408.9 EKX46692.1 - 0.34 9.5 2.0 0.48 9.0 2.0 1.1 1 0 0 1 1 1 0 Ubiquitin elongating factor core RIFIN PF02009.16 EKX46692.1 - 0.37 10.7 0.0 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 Rifin EGF_2 PF07974.13 EKX46692.1 - 3.3 8.2 35.9 2.5 8.5 4.2 4.5 3 0 0 3 3 3 0 EGF-like domain RWP-RK PF02042.15 EKX46694.1 - 1.5e-12 47.3 0.0 3.3e-12 46.2 0.0 1.6 1 1 1 2 2 2 1 RWP-RK domain MttA_Hcf106 PF02416.16 EKX46694.1 - 0.0014 17.9 0.1 0.0022 17.3 0.1 1.3 1 0 0 1 1 1 1 mttA/Hcf106 family HTH_23 PF13384.6 EKX46694.1 - 0.17 11.7 0.0 0.93 9.4 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain Myb_DNA-binding PF00249.31 EKX46696.1 - 6.3e-05 23.1 0.2 0.00019 21.6 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain GalP_UDP_transf PF01087.22 EKX46696.1 - 0.1 13.0 1.8 0.18 12.2 1.7 1.3 1 1 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, N-terminal domain SpoU_methylase PF00588.19 EKX46697.1 - 1.1e-31 109.9 0.1 2.1e-31 109.0 0.1 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family SIR2 PF02146.17 EKX46698.1 - 2.1e-58 197.2 0.0 2.5e-58 196.9 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EKX46698.1 - 0.00013 21.7 0.0 0.0037 17.0 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Cytochrom_CIII PF02085.16 EKX46698.1 - 0.09 13.1 0.2 0.15 12.5 0.2 1.3 1 0 0 1 1 1 0 Class III cytochrome C family WD40 PF00400.32 EKX46699.1 - 3.9e-83 271.2 20.9 3.6e-08 33.9 0.0 12.0 12 0 0 12 12 12 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX46699.1 - 1.5e-25 89.3 1.2 0.0018 18.6 0.1 8.4 2 2 8 10 10 10 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX46699.1 - 3.5e-06 26.2 0.1 0.69 8.8 0.1 6.1 2 1 4 8 8 8 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EKX46699.1 - 1.7e-05 23.7 0.2 8.1 5.1 0.0 5.4 3 2 3 6 6 6 2 Nup133 N terminal like Nup160 PF11715.8 EKX46699.1 - 2.1e-05 23.4 1.8 2.5 6.6 0.1 6.1 5 2 2 7 7 7 1 Nucleoporin Nup120/160 eIF2A PF08662.11 EKX46699.1 - 4e-05 23.6 0.0 0.057 13.3 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A DUF1513 PF07433.11 EKX46699.1 - 0.0041 16.2 1.5 7.9 5.5 0.3 4.1 3 2 2 5 5 5 1 Protein of unknown function (DUF1513) Ricin_B_lectin PF00652.22 EKX46699.1 - 0.014 15.7 0.0 0.059 13.6 0.0 2.1 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain Hira PF07569.11 EKX46699.1 - 0.05 13.3 0.0 16 5.1 0.0 4.0 5 0 0 5 5 5 0 TUP1-like enhancer of split IKI3 PF04762.12 EKX46699.1 - 0.11 10.5 3.0 0.48 8.4 0.3 2.8 1 1 0 2 2 2 0 IKI3 family Coatomer_WDAD PF04053.14 EKX46699.1 - 0.12 11.4 0.0 0.46 9.5 0.0 2.1 3 0 0 3 3 3 0 Coatomer WD associated region NACHT PF05729.12 EKX46700.1 - 1.2e-06 28.5 0.0 1.5e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 EKX46700.1 - 0.001 18.3 0.0 0.0012 18.1 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_30 PF13604.6 EKX46700.1 - 0.002 17.9 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EKX46700.1 - 0.0027 18.0 0.0 0.0035 17.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EKX46700.1 - 0.0033 16.6 0.1 0.0041 16.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 EKX46700.1 - 0.004 17.6 0.0 0.0049 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 EKX46700.1 - 0.005 16.3 0.0 0.0059 16.0 0.0 1.0 1 0 0 1 1 1 1 Bacterial TniB protein DUF87 PF01935.17 EKX46700.1 - 0.011 15.9 0.0 0.021 14.9 0.0 1.5 1 1 0 1 1 1 0 Helicase HerA, central domain ABC_tran PF00005.27 EKX46700.1 - 0.018 15.6 0.1 0.045 14.3 0.1 1.7 1 1 1 2 2 2 0 ABC transporter ATPase_2 PF01637.18 EKX46700.1 - 0.033 14.1 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Roc PF08477.13 EKX46700.1 - 0.038 14.2 0.0 0.054 13.7 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MobB PF03205.14 EKX46700.1 - 0.066 13.1 0.2 0.31 10.9 0.1 1.9 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2075 PF09848.9 EKX46700.1 - 0.068 12.4 0.0 0.1 11.8 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 EKX46700.1 - 0.068 12.3 0.0 0.081 12.1 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase RNA_helicase PF00910.22 EKX46700.1 - 0.099 13.0 0.1 0.26 11.7 0.1 1.7 1 1 1 2 2 2 0 RNA helicase cobW PF02492.19 EKX46700.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EKX46700.1 - 0.11 12.3 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase Viral_helicase1 PF01443.18 EKX46700.1 - 0.12 12.1 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DLIC PF05783.11 EKX46700.1 - 0.13 11.1 0.0 0.25 10.1 0.0 1.5 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) TrwB_AAD_bind PF10412.9 EKX46700.1 - 0.15 11.0 0.0 0.24 10.3 0.0 1.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 EKX46700.1 - 0.17 11.9 0.0 0.19 11.7 0.0 1.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EKX46700.1 - 0.18 12.1 0.0 0.24 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Golgin_A5 PF09787.9 EKX46702.1 - 0.0048 16.4 15.0 0.0048 16.4 15.0 3.4 3 1 0 3 3 3 1 Golgin subfamily A member 5 CHB_HEX_C_1 PF13290.6 EKX46702.1 - 0.031 14.3 0.0 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain Spc7 PF08317.11 EKX46702.1 - 0.094 11.6 44.0 0.016 14.1 14.4 4.1 3 2 0 3 3 3 0 Spc7 kinetochore protein HALZ PF02183.18 EKX46702.1 - 0.17 12.1 3.2 0.19 12.0 0.1 2.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper Tup_N PF08581.10 EKX46702.1 - 0.42 10.9 35.6 1.8 8.9 0.6 6.5 5 2 1 6 6 6 0 Tup N-terminal PKcGMP_CC PF16808.5 EKX46702.1 - 0.46 10.4 15.3 0.053 13.4 1.0 4.9 4 1 1 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SOGA PF11365.8 EKX46702.1 - 2.9 9.1 28.6 0.6 11.3 2.5 4.8 3 2 1 4 4 4 0 Protein SOGA DUF3967 PF13152.6 EKX46702.1 - 4.7 7.1 14.0 0.71 9.7 0.2 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3967) HEAT PF02985.22 EKX46703.1 - 6.5e-07 29.1 1.2 8.5 6.9 0.0 7.2 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.6 EKX46703.1 - 1.7e-05 25.1 0.1 6.6 7.2 0.0 6.4 6 1 0 7 7 7 1 HEAT repeats Cnd1 PF12717.7 EKX46703.1 - 2.5e-05 24.4 5.7 0.99 9.4 0.0 6.0 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Endopep_inhib PF16800.5 EKX46703.1 - 0.00036 20.5 5.6 0.23 11.4 0.3 2.5 2 0 0 2 2 2 2 IseA DL-endopeptidase inhibitor Cohesin_HEAT PF12765.7 EKX46703.1 - 0.17 12.2 2.0 4.3 7.7 0.0 3.7 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion cobW PF02492.19 EKX46704.1 - 8.7e-52 175.3 1.7 1.2e-51 174.8 1.7 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EKX46704.1 - 1.2e-11 44.3 0.0 2.5e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.27 EKX46704.1 - 2.2e-05 24.1 0.0 0.00017 21.2 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EKX46704.1 - 0.0057 17.1 0.3 0.028 14.8 0.0 2.2 3 0 0 3 3 3 1 AAA ATPase domain Viral_helicase1 PF01443.18 EKX46704.1 - 0.0064 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EKX46704.1 - 0.0067 16.7 0.6 0.019 15.2 0.6 2.0 1 1 0 1 1 1 1 AAA domain MobB PF03205.14 EKX46704.1 - 0.01 15.8 0.0 0.026 14.4 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 EKX46704.1 - 0.021 15.0 0.3 0.047 13.8 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EKX46704.1 - 0.023 15.3 0.0 0.039 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EKX46704.1 - 0.024 14.6 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 EKX46704.1 - 0.03 14.2 1.1 1.7 8.5 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase MeaB PF03308.16 EKX46704.1 - 0.049 12.6 0.3 0.13 11.2 0.3 1.6 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 EKX46704.1 - 0.072 12.6 0.7 0.2 11.1 0.1 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_14 PF13173.6 EKX46704.1 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EKX46704.1 - 0.13 12.1 0.2 0.38 10.7 0.1 1.8 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 EKX46704.1 - 0.18 11.9 0.7 2.4 8.3 0.7 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase Arf PF00025.21 EKX46704.1 - 0.42 10.0 1.6 10 5.5 0.1 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family Peptidase_S24 PF00717.23 EKX46705.1 - 5.8e-09 35.8 0.0 1.1e-08 34.9 0.0 1.5 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EKX46705.1 - 0.00029 20.6 0.0 0.073 12.9 0.0 2.4 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 ToxB_N PF18224.1 EKX46705.1 - 0.0033 17.3 0.0 0.0056 16.6 0.0 1.3 1 0 0 1 1 1 1 ToxB N-terminal domain Polbeta PF18765.1 EKX46706.1 - 0.12 12.4 0.1 21 5.3 0.0 2.6 3 1 0 3 3 3 0 Polymerase beta, Nucleotidyltransferase Zn_Tnp_IS1 PF03811.13 EKX46707.1 - 0.11 12.3 3.6 0.68 9.7 0.4 2.9 2 0 0 2 2 2 0 InsA N-terminal domain NIF PF03031.18 EKX46709.1 - 1.2e-09 38.1 0.0 3e-09 36.8 0.0 1.6 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase HEAT PF02985.22 EKX46711.1 - 1.7e-20 71.3 9.9 0.0001 22.3 0.0 10.9 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.6 EKX46711.1 - 1.5e-16 60.5 7.3 1.9e-07 31.4 0.0 8.0 8 1 2 10 10 9 4 HEAT-like repeat HEAT_2 PF13646.6 EKX46711.1 - 1.3e-12 48.0 0.0 0.016 15.6 0.0 7.0 6 2 1 7 7 7 2 HEAT repeats Cnd1 PF12717.7 EKX46711.1 - 6.4e-09 36.1 0.6 0.3 11.1 0.0 5.4 4 1 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EKX46711.1 - 9e-08 31.1 0.3 0.31 9.5 0.5 4.3 3 2 1 4 4 4 3 Adaptin N terminal region IBN_N PF03810.19 EKX46711.1 - 2.4e-07 30.5 0.0 1.9e-06 27.7 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 EKX46711.1 - 1.9e-06 28.3 0.0 6.4 7.5 0.0 5.8 6 1 0 6 6 6 1 Vacuolar 14 Fab1-binding region Arm PF00514.23 EKX46711.1 - 5.5e-06 26.2 9.6 0.025 14.6 0.0 7.2 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat Katanin_con80 PF13925.6 EKX46711.1 - 0.0012 18.9 0.0 0.0046 17.0 0.0 2.0 1 0 0 1 1 1 1 con80 domain of Katanin TAF6_C PF07571.13 EKX46711.1 - 0.0022 18.3 0.1 0.38 11.1 0.0 4.2 3 2 1 4 4 4 1 TAF6 C-terminal HEAT repeat domain IFRD PF05004.13 EKX46711.1 - 0.0027 16.9 0.0 0.074 12.1 0.0 2.6 2 1 0 2 2 2 1 Interferon-related developmental regulator (IFRD) Proteasom_PSMB PF10508.9 EKX46711.1 - 0.0066 15.0 0.0 0.017 13.6 0.0 1.7 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit Dopey_N PF04118.14 EKX46711.1 - 0.013 14.6 1.3 0.24 10.5 0.1 3.0 3 1 0 3 3 3 0 Dopey, N-terminal CLASP_N PF12348.8 EKX46711.1 - 0.015 14.9 2.6 38 3.7 0.0 5.3 5 1 0 6 6 6 0 CLASP N terminal MMS19_C PF12460.8 EKX46711.1 - 0.042 12.9 0.0 1.7 7.7 0.0 3.3 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal Utp12 PF04003.12 EKX46711.1 - 0.07 13.4 0.2 0.4 11.0 0.0 2.4 2 0 0 2 2 1 0 Dip2/Utp12 Family DUF4042 PF13251.6 EKX46711.1 - 0.087 12.5 0.1 48 3.6 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) C2 PF00168.30 EKX46712.1 - 4.2e-08 33.4 0.0 8e-08 32.5 0.0 1.4 2 0 0 2 2 2 1 C2 domain ASD1 PF08688.10 EKX46712.1 - 0.025 15.0 0.0 0.025 15.0 0.0 1.2 1 0 0 1 1 1 0 Apx/Shroom domain ASD1 Ank_5 PF13857.6 EKX46714.1 - 1.7e-15 56.9 0.6 1.7e-09 37.8 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX46714.1 - 2e-14 53.7 0.0 1.1e-07 32.2 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX46714.1 - 3.8e-11 42.9 0.1 1.1e-07 32.0 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EKX46714.1 - 3.5e-10 40.3 0.1 2.1e-09 37.9 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX46714.1 - 5.3e-09 35.6 0.0 1.8e-06 27.8 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Y_phosphatase PF00102.27 EKX46715.1 - 5.2e-05 22.9 0.0 6.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX46715.1 - 0.00011 22.4 0.0 0.00018 21.6 0.0 1.7 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EKX46715.1 - 0.0006 19.8 0.0 0.00081 19.4 0.0 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EKX46715.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.5 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 EKX46715.1 - 0.012 15.3 0.2 0.016 14.9 0.2 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) LRR_8 PF13855.6 EKX46716.1 - 2.7e-107 350.5 86.2 6.1e-17 61.1 6.4 10.1 1 1 9 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 EKX46716.1 - 9.2e-45 149.9 91.5 4.7e-06 26.8 3.2 11.6 2 2 9 14 14 14 14 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX46716.1 - 5.1e-44 149.3 0.0 6.5e-09 35.8 0.0 5.2 1 1 4 5 5 5 5 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EKX46716.1 - 9.5e-14 49.8 82.4 2 9.3 0.1 18.1 18 2 0 18 18 18 7 Leucine Rich Repeat LRR_9 PF14580.6 EKX46716.1 - 1.7e-13 50.4 8.2 0.055 13.0 0.1 6.4 1 1 6 7 7 7 6 Leucine-rich repeat Aldolase PF01081.19 EKX46716.1 - 0.00017 21.1 0.0 33 3.8 0.0 5.3 1 1 6 8 8 8 0 KDPG and KHG aldolase DUF4516 PF14990.6 EKX46716.1 - 0.0078 15.9 0.0 9.4 6.1 0.0 5.7 10 0 0 10 10 10 1 Domain of unknown function (DUF4516) Ribosomal_S5_C PF03719.15 EKX46716.1 - 0.0093 15.4 0.0 3.7 7.1 0.0 5.1 6 2 1 7 7 7 1 Ribosomal protein S5, C-terminal domain MFS_1 PF07690.16 EKX46719.1 - 7.6e-06 25.1 7.1 9e-06 24.8 7.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CH PF00307.31 EKX46720.1 - 2.8e-75 249.5 7.3 3.8e-21 75.3 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EKX46720.1 - 8.5e-07 28.7 0.2 0.014 15.2 0.0 4.0 4 0 0 4 4 4 2 CAMSAP CH domain TraF PF13728.6 EKX46720.1 - 0.0045 16.8 0.1 0.0045 16.8 0.1 2.4 1 1 1 2 2 2 1 F plasmid transfer operon protein CH_2 PF06294.11 EKX46720.1 - 0.032 14.4 0.1 26 5.0 0.1 3.5 3 0 0 3 3 3 0 CH-like domain in sperm protein Ndc1_Nup PF09531.10 EKX46720.1 - 1.5 7.4 5.0 2.3 6.8 5.0 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Kinesin PF00225.23 EKX46721.1 - 1.5e-109 366.0 0.1 3.3e-109 364.9 0.1 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX46721.1 - 2.7e-27 95.5 0.0 9e-27 93.8 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding TLD PF07534.16 EKX46722.1 - 1.5e-09 38.2 0.0 2.2e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 TLD 2_5_RNA_ligase2 PF13563.6 EKX46723.1 - 7.9e-08 32.4 0.0 1.9e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily U79_P34 PF03064.16 EKX46723.1 - 1.8 7.9 14.4 3.9 6.8 14.4 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Ephrin_rec_like PF07699.13 EKX46724.1 - 4.7e-21 74.3 53.7 2e-05 24.2 3.2 7.3 3 1 4 7 7 7 7 Putative ephrin-receptor like NCD3G PF07562.14 EKX46724.1 - 5.4e-12 45.5 35.6 0.078 13.0 0.0 7.0 5 1 3 8 8 8 8 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX46724.1 - 0.37 11.2 0.3 0.37 11.2 0.3 7.4 7 2 0 7 7 7 0 TNFR/NGFR cysteine-rich region VSP PF03302.13 EKX46724.1 - 1.2 7.9 42.1 0.82 8.5 17.5 3.3 1 1 2 3 3 3 0 Giardia variant-specific surface protein DSPn PF14671.6 EKX46726.1 - 1.2e-20 74.4 0.0 8.2e-20 71.7 0.0 2.1 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EKX46726.1 - 1.6e-09 37.6 0.0 2.8e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX46726.1 - 0.0079 15.8 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Ofd1_CTDD PF10637.9 EKX46727.1 - 3.2e-29 102.0 10.5 3.7e-18 65.8 1.9 3.9 2 1 1 3 3 3 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 EKX46727.1 - 6.2e-12 46.0 0.0 1.4e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EKX46727.1 - 0.00015 22.6 0.0 0.00028 21.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1963 PF09234.10 EKX46727.1 - 0.06 13.8 0.1 0.15 12.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1963) CEP19 PF14933.6 EKX46727.1 - 0.092 13.0 2.4 0.21 11.9 2.4 1.5 1 0 0 1 1 1 0 CEP19-like protein CLPTM1 PF05602.12 EKX46728.1 - 2.4e-75 254.2 0.8 3e-75 253.9 0.8 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 EKX46728.1 - 0.016 14.9 0.1 0.15 11.9 0.0 2.5 2 0 0 2 2 2 0 PQ loop repeat DASH_Dam1 PF08653.10 EKX46729.1 - 1e-08 34.8 1.2 0.052 13.4 0.1 3.7 2 1 1 3 3 3 2 DASH complex subunit Dam1 Syntaxin-6_N PF09177.11 EKX46729.1 - 6e-06 26.7 6.5 0.034 14.7 2.8 3.8 1 1 2 3 3 3 3 Syntaxin 6, N-terminal Spc7 PF08317.11 EKX46729.1 - 1.4e-05 24.1 11.3 3.9e-05 22.7 11.3 1.7 1 0 0 1 1 1 1 Spc7 kinetochore protein AIP3 PF03915.13 EKX46729.1 - 2.2e-05 23.8 4.1 3.3e-05 23.2 4.1 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 Gp58 PF07902.11 EKX46729.1 - 2.2e-05 23.0 2.2 3.3e-05 22.4 2.2 1.2 1 0 0 1 1 1 1 gp58-like protein DUF3584 PF12128.8 EKX46729.1 - 3.4e-05 21.6 9.6 4.8e-05 21.1 9.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Vps51 PF08700.11 EKX46729.1 - 4.2e-05 23.5 8.5 0.9 9.7 0.2 3.7 3 0 0 3 3 3 2 Vps51/Vps67 UPF0242 PF06785.11 EKX46729.1 - 4.8e-05 23.6 5.9 8.7e-05 22.7 5.9 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus TACC_C PF05010.14 EKX46729.1 - 5.9e-05 22.9 15.5 0.00021 21.2 15.5 1.8 1 1 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal FlaC_arch PF05377.11 EKX46729.1 - 7.4e-05 23.1 14.3 0.05 14.0 0.5 4.2 2 1 2 4 4 4 1 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.12 EKX46729.1 - 0.00011 22.3 12.8 0.00086 19.4 12.3 2.6 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein CCDC144C PF14915.6 EKX46729.1 - 0.00011 21.5 16.7 0.00029 20.1 10.6 2.1 1 1 1 2 2 2 2 CCDC144C protein coiled-coil region BLOC1_2 PF10046.9 EKX46729.1 - 0.0002 21.6 13.9 0.031 14.6 1.8 2.8 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 HMMR_N PF15905.5 EKX46729.1 - 0.00024 20.7 15.8 0.0004 20.0 15.8 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal PI3K_P85_iSH2 PF16454.5 EKX46729.1 - 0.00026 20.6 14.7 0.0035 16.9 13.9 3.1 1 1 1 2 2 2 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF1664 PF07889.12 EKX46729.1 - 0.00027 21.0 13.5 0.071 13.1 6.0 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) Csm1_N PF18504.1 EKX46729.1 - 0.00027 21.2 14.4 0.71 10.3 0.8 4.4 1 1 3 4 4 4 2 Csm1 N-terminal domain DUF4618 PF15397.6 EKX46729.1 - 0.00036 20.1 14.4 0.02 14.3 10.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4618) Apolipoprotein PF01442.18 EKX46729.1 - 0.00038 20.4 8.5 0.00065 19.6 8.5 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Lectin_N PF03954.14 EKX46729.1 - 0.00043 20.0 9.2 0.012 15.3 2.2 2.7 1 1 2 3 3 3 3 Hepatic lectin, N-terminal domain AKNA PF12443.8 EKX46729.1 - 0.00069 20.2 12.8 1.3 9.7 2.2 3.5 1 1 2 3 3 3 0 AT-hook-containing transcription factor Exonuc_VII_L PF02601.15 EKX46729.1 - 0.00074 19.2 2.6 0.0011 18.6 2.6 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit Leu_zip PF15294.6 EKX46729.1 - 0.00074 19.1 13.2 0.0013 18.3 13.2 1.3 1 0 0 1 1 1 1 Leucine zipper Spectrin PF00435.21 EKX46729.1 - 0.0009 19.7 13.6 0.0016 18.9 8.6 2.4 1 1 1 2 2 2 1 Spectrin repeat NPV_P10 PF05531.12 EKX46729.1 - 0.00098 19.5 9.9 0.69 10.4 2.8 3.4 1 1 2 3 3 3 2 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.22 EKX46729.1 - 0.001 19.3 17.1 0.19 12.0 9.4 3.1 1 1 1 2 2 2 2 Seryl-tRNA synthetase N-terminal domain Snapin_Pallidin PF14712.6 EKX46729.1 - 0.001 19.4 12.4 0.12 12.9 2.8 2.6 2 0 0 2 2 2 2 Snapin/Pallidin ZapB PF06005.12 EKX46729.1 - 0.0011 19.4 17.1 0.1 13.0 0.4 3.5 1 1 1 2 2 2 1 Cell division protein ZapB EzrA PF06160.12 EKX46729.1 - 0.0013 17.0 10.6 0.0022 16.3 10.6 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Rbsn PF11464.8 EKX46729.1 - 0.0026 17.5 2.7 19 5.0 0.0 4.1 3 0 0 3 3 3 0 Rabenosyn Rab binding domain Fib_alpha PF08702.10 EKX46729.1 - 0.0026 18.0 10.6 0.0093 16.2 8.0 2.5 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family GAS PF13851.6 EKX46729.1 - 0.0033 16.8 18.9 0.0095 15.3 14.0 2.9 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 EKX46729.1 - 0.0034 17.9 11.7 0.0084 16.6 11.7 1.6 1 0 0 1 1 1 1 Fez1 CCDC154 PF15450.6 EKX46729.1 - 0.0037 15.9 13.0 0.0056 15.3 13.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 154 DivIC PF04977.15 EKX46729.1 - 0.005 16.6 11.3 0.25 11.1 0.2 3.6 2 1 1 3 3 3 1 Septum formation initiator Filament PF00038.21 EKX46729.1 - 0.0059 16.2 17.8 0.0077 15.9 14.2 2.5 2 1 0 2 2 1 1 Intermediate filament protein DUF948 PF06103.11 EKX46729.1 - 0.0067 16.7 9.2 0.36 11.1 2.2 2.6 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 EKX46729.1 - 0.0072 16.4 0.7 0.018 15.1 0.7 1.7 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Fzo_mitofusin PF04799.13 EKX46729.1 - 0.0075 15.8 11.4 0.18 11.3 2.1 3.2 1 1 2 3 3 3 1 fzo-like conserved region Prefoldin PF02996.17 EKX46729.1 - 0.0081 16.1 11.7 0.52 10.2 1.3 3.7 2 1 2 4 4 3 1 Prefoldin subunit Syntaxin PF00804.25 EKX46729.1 - 0.0099 15.6 13.0 0.67 9.6 2.7 2.7 1 1 1 2 2 2 2 Syntaxin SlyX PF04102.12 EKX46729.1 - 0.012 16.2 12.2 5.3 7.7 0.5 4.2 1 1 2 3 3 3 0 SlyX Muted PF14942.6 EKX46729.1 - 0.013 15.9 15.1 0.29 11.5 13.6 2.4 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Med9 PF07544.13 EKX46729.1 - 0.013 15.6 4.1 0.013 15.6 4.1 2.8 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TelA PF05816.11 EKX46729.1 - 0.015 14.4 13.5 0.022 13.8 13.5 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) ADIP PF11559.8 EKX46729.1 - 0.016 15.3 11.6 0.016 15.3 11.6 2.2 2 1 0 2 2 1 0 Afadin- and alpha -actinin-Binding DUF4795 PF16043.5 EKX46729.1 - 0.017 14.7 15.8 0.043 13.4 15.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) THOC7 PF05615.13 EKX46729.1 - 0.02 15.2 12.1 5.5 7.3 0.6 3.3 1 1 1 2 2 2 0 Tho complex subunit 7 KxDL PF10241.9 EKX46729.1 - 0.02 15.2 9.5 0.79 10.0 0.4 3.2 1 1 2 3 3 3 0 Uncharacterized conserved protein DUF677 PF05055.12 EKX46729.1 - 0.021 13.8 10.0 0.066 12.1 10.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF677) YabA PF06156.13 EKX46729.1 - 0.025 15.2 3.9 0.025 15.2 3.9 2.7 1 1 1 2 2 2 0 Initiation control protein YabA PfUIS3 PF11567.8 EKX46729.1 - 0.026 14.9 9.5 9.8 6.6 2.3 4.3 2 2 3 5 5 5 0 Plasmodium falciparum UIS3 membrane protein WXG100 PF06013.12 EKX46729.1 - 0.028 14.7 8.1 3.6 7.9 0.2 3.3 1 1 2 3 3 3 0 Proteins of 100 residues with WXG DUF812 PF05667.11 EKX46729.1 - 0.029 13.3 16.3 0.065 12.1 16.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) AAA_13 PF13166.6 EKX46729.1 - 0.029 13.0 7.0 0.044 12.4 7.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3972 PF13118.6 EKX46729.1 - 0.029 14.8 10.1 0.083 13.3 5.8 2.8 2 1 1 3 3 2 0 Protein of unknown function (DUF3972) CALCOCO1 PF07888.11 EKX46729.1 - 0.033 13.1 13.7 0.07 12.0 13.7 1.5 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like SKA2 PF16740.5 EKX46729.1 - 0.037 13.8 10.6 0.055 13.3 7.3 2.4 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 AP_endonuc_2_N PF07582.12 EKX46729.1 - 0.038 13.7 0.6 16 5.3 0.0 3.4 3 0 0 3 3 3 0 AP endonuclease family 2 C terminus DUF16 PF01519.16 EKX46729.1 - 0.045 14.2 19.9 0.48 10.9 9.8 2.8 2 1 1 3 3 2 0 Protein of unknown function DUF16 CorA PF01544.18 EKX46729.1 - 0.047 13.0 5.1 0.087 12.1 5.1 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Tmemb_cc2 PF10267.9 EKX46729.1 - 0.048 12.8 17.7 0.52 9.4 11.8 2.3 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein HIP1_clath_bdg PF16515.5 EKX46729.1 - 0.052 14.2 19.6 1.7 9.3 7.9 2.9 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Phage_GPO PF05929.11 EKX46729.1 - 0.056 13.1 11.8 0.17 11.5 5.8 2.1 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Rab5-bind PF09311.11 EKX46729.1 - 0.06 12.7 11.7 0.11 11.8 11.7 1.4 1 0 0 1 1 1 0 Rabaptin-like protein Alpha-E PF04168.12 EKX46729.1 - 0.064 13.0 3.9 0.21 11.3 0.6 2.2 1 1 1 2 2 2 0 A predicted alpha-helical domain with a conserved ER motif. APG17 PF04108.12 EKX46729.1 - 0.07 12.2 8.5 0.63 9.1 5.1 2.0 1 1 0 1 1 1 0 Autophagy protein Apg17 FmiP_Thoc5 PF09766.9 EKX46729.1 - 0.072 12.4 11.7 0.69 9.1 9.4 2.5 1 1 1 2 2 2 0 Fms-interacting protein/Thoc5 DUF4407 PF14362.6 EKX46729.1 - 0.075 12.4 8.3 0.29 10.4 8.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HALZ PF02183.18 EKX46729.1 - 0.075 13.3 10.4 1.7 8.9 0.1 4.0 3 1 0 3 3 3 0 Homeobox associated leucine zipper MbeD_MobD PF04899.12 EKX46729.1 - 0.077 13.1 4.6 15 5.8 0.1 3.4 1 1 2 3 3 3 0 MbeD/MobD like DUF5082 PF16888.5 EKX46729.1 - 0.081 13.2 8.4 0.7 10.2 8.3 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) HalX PF08663.10 EKX46729.1 - 0.081 13.2 2.8 16 5.9 0.1 3.5 1 1 2 3 3 3 0 HalX domain HOOK PF05622.12 EKX46729.1 - 0.085 11.0 18.5 0.55 8.3 18.0 1.9 1 1 1 2 2 2 0 HOOK protein Laminin_II PF06009.12 EKX46729.1 - 0.086 12.9 9.7 1.1 9.2 6.6 2.7 1 1 1 2 2 2 0 Laminin Domain II DUF2730 PF10805.8 EKX46729.1 - 0.093 12.8 10.9 0.43 10.7 4.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Lebercilin PF15619.6 EKX46729.1 - 0.096 12.3 23.4 0.081 12.6 17.6 2.7 2 1 0 2 2 1 0 Ciliary protein causing Leber congenital amaurosis disease RmuC PF02646.16 EKX46729.1 - 0.097 11.8 13.2 0.32 10.1 2.6 2.5 1 1 0 2 2 2 0 RmuC family Helo_like_N PF17111.5 EKX46729.1 - 0.1 11.9 9.7 2.7 7.3 0.1 3.6 2 1 2 4 4 3 0 Fungal N-terminal domain of STAND proteins LXG PF04740.12 EKX46729.1 - 0.11 12.2 11.9 2.6 7.7 0.3 3.0 1 1 1 2 2 2 0 LXG domain of WXG superfamily ABC_tran_CTD PF16326.5 EKX46729.1 - 0.11 12.8 9.7 0.21 11.9 3.3 2.7 1 1 1 2 2 2 0 ABC transporter C-terminal domain SHE3 PF17078.5 EKX46729.1 - 0.11 12.2 12.5 0.39 10.4 12.5 1.8 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF2959 PF11172.8 EKX46729.1 - 0.11 12.6 6.0 0.45 10.6 6.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2959) Nmad5 PF18757.1 EKX46729.1 - 0.11 12.7 7.5 3.9 7.6 7.5 2.9 1 1 0 1 1 1 0 Nucleotide modification associated domain 5 DUF5631 PF18645.1 EKX46729.1 - 0.12 12.8 0.2 17 5.9 0.0 2.9 1 1 1 2 2 2 0 Family of unknown function (DUF5631) ApoLp-III PF07464.11 EKX46729.1 - 0.12 12.4 10.1 0.48 10.5 10.1 1.9 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF4988 PF16378.5 EKX46729.1 - 0.13 12.0 5.7 2.2 7.9 0.2 3.1 1 1 1 2 2 2 0 Domain of unknown function Golgin_A5 PF09787.9 EKX46729.1 - 0.15 11.5 17.3 0.29 10.6 14.0 2.0 1 1 1 2 2 2 0 Golgin subfamily A member 5 YkyA PF10368.9 EKX46729.1 - 0.15 11.7 16.4 0.097 12.3 7.9 2.2 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein FliJ PF02050.16 EKX46729.1 - 0.16 12.2 8.8 1.5 9.1 7.1 2.4 1 1 1 2 2 2 0 Flagellar FliJ protein XhlA PF10779.9 EKX46729.1 - 0.16 12.2 14.5 1.1 9.5 3.4 3.8 1 1 2 3 3 3 0 Haemolysin XhlA LPP PF04728.13 EKX46729.1 - 0.16 12.4 6.5 14 6.2 0.1 3.8 4 0 0 4 4 3 0 Lipoprotein leucine-zipper DUF3450 PF11932.8 EKX46729.1 - 0.18 11.1 13.3 0.99 8.7 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CEP63 PF17045.5 EKX46729.1 - 0.18 11.7 15.9 0.32 10.9 6.8 2.2 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa Allexi_40kDa PF05549.11 EKX46729.1 - 0.2 11.1 8.2 0.14 11.6 0.7 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein YscO PF07321.12 EKX46729.1 - 0.22 11.5 11.3 5 7.1 0.2 3.0 1 1 1 2 2 2 0 Type III secretion protein YscO Occludin_ELL PF07303.13 EKX46729.1 - 0.23 12.2 14.6 0.1 13.3 2.3 3.3 3 1 1 4 4 2 0 Occludin homology domain DUF724 PF05266.14 EKX46729.1 - 0.23 11.3 16.7 2.5 7.9 6.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) bZIP_1 PF00170.21 EKX46729.1 - 0.23 11.6 24.1 0.13 12.4 1.0 4.5 3 1 1 4 4 4 0 bZIP transcription factor Ax_dynein_light PF10211.9 EKX46729.1 - 0.25 11.3 17.4 0.14 12.1 6.1 2.6 1 1 2 3 3 3 0 Axonemal dynein light chain Atg14 PF10186.9 EKX46729.1 - 0.26 10.3 7.3 0.53 9.3 6.9 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CK2S PF15011.6 EKX46729.1 - 0.26 11.1 10.6 3.2 7.6 4.8 3.3 1 1 2 3 3 3 0 Casein Kinase 2 substrate Zw10 PF06248.13 EKX46729.1 - 0.28 9.7 5.8 0.4 9.2 5.8 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 CENP-K PF11802.8 EKX46729.1 - 0.29 10.7 14.1 0.79 9.2 14.1 1.7 1 1 0 1 1 1 0 Centromere-associated protein K V_ATPase_I PF01496.19 EKX46729.1 - 0.29 9.0 7.4 0.43 8.4 7.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DASH_Dad2 PF08654.10 EKX46729.1 - 0.29 11.6 8.3 2.5 8.6 0.1 3.5 2 1 1 3 3 3 0 DASH complex subunit Dad2 Phage_HK97_TLTM PF06120.11 EKX46729.1 - 0.32 10.1 11.9 1.3 8.1 5.2 2.3 1 1 1 2 2 2 0 Tail length tape measure protein ORF6C PF10552.9 EKX46729.1 - 0.34 11.0 11.9 3.5 7.7 0.6 4.0 2 1 2 4 4 3 0 ORF6C domain Dabb PF07876.12 EKX46729.1 - 0.34 11.6 6.7 5.6 7.7 0.1 3.5 1 1 2 3 3 3 0 Stress responsive A/B Barrel Domain T3SSipB PF16535.5 EKX46729.1 - 0.35 11.4 7.2 1.1 9.7 1.5 2.5 1 1 1 2 2 2 0 Type III cell invasion protein SipB Cytochrom_B562 PF07361.11 EKX46729.1 - 0.36 11.5 13.7 3.3 8.4 3.5 2.6 1 1 1 2 2 2 0 Cytochrome b562 Prefoldin_2 PF01920.20 EKX46729.1 - 0.36 10.8 19.9 5 7.1 3.5 3.4 1 1 1 2 2 2 0 Prefoldin subunit PspA_IM30 PF04012.12 EKX46729.1 - 0.37 10.3 16.3 0.46 10.0 0.9 3.3 1 1 1 2 2 2 0 PspA/IM30 family DUF4175 PF13779.6 EKX46729.1 - 0.38 8.6 15.0 0.55 8.1 15.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Phage_GP20 PF06810.11 EKX46729.1 - 0.38 10.5 19.3 4.4 7.1 7.8 3.3 1 1 1 3 3 3 0 Phage minor structural protein GP20 Spc29 PF17082.5 EKX46729.1 - 0.48 10.2 7.9 3.8 7.3 0.8 2.4 1 1 1 2 2 2 0 Spindle Pole Component 29 DUF4164 PF13747.6 EKX46729.1 - 0.54 10.6 7.7 1.2 9.4 1.7 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) KfrA_N PF11740.8 EKX46729.1 - 0.54 10.9 5.5 13 6.5 0.7 3.1 1 1 2 3 3 3 0 Plasmid replication region DNA-binding N-term Prominin PF05478.11 EKX46729.1 - 0.57 8.1 10.1 0.98 7.3 4.5 2.0 1 1 1 2 2 2 0 Prominin Sec20 PF03908.13 EKX46729.1 - 0.61 10.0 5.6 11 6.0 0.5 2.8 1 1 2 3 3 3 0 Sec20 MAD PF05557.13 EKX46729.1 - 0.65 8.3 17.3 1.7 6.9 17.3 1.6 1 1 0 1 1 1 0 Mitotic checkpoint protein Jnk-SapK_ap_N PF09744.9 EKX46729.1 - 0.79 9.9 17.4 0.35 11.1 7.0 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 EKX46729.1 - 0.91 10.1 16.6 1.5 9.3 5.5 3.2 2 1 1 3 3 3 0 Apg6 coiled-coil region DUF641 PF04859.12 EKX46729.1 - 0.96 9.8 12.1 4.4 7.6 5.2 2.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Tektin PF03148.14 EKX46729.1 - 1.1 7.9 15.6 1.6 7.4 7.3 2.6 1 1 1 2 2 2 0 Tektin family Bacillus_HBL PF05791.11 EKX46729.1 - 1.3 8.8 9.5 5.7 6.7 9.5 2.0 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) HrpB7 PF09486.10 EKX46729.1 - 1.4 9.3 5.9 2.1 8.7 3.8 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Sulfatase_C PF14707.6 EKX46729.1 - 1.5 9.6 4.5 25 5.6 0.9 2.8 1 1 2 3 3 3 0 C-terminal region of aryl-sulfatase TMPIT PF07851.13 EKX46729.1 - 1.5 8.0 12.8 3 7.0 5.0 2.0 1 1 1 2 2 2 0 TMPIT-like protein AAA_32 PF13654.6 EKX46729.1 - 1.5 7.5 11.5 2.1 7.0 3.0 1.9 1 1 1 2 2 2 0 AAA domain CLZ PF16526.5 EKX46729.1 - 1.7 9.1 17.1 0.58 10.6 2.0 3.3 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Mt_ATP-synt_D PF05873.12 EKX46729.1 - 1.7 8.5 9.6 2.1e+02 1.7 3.1 3.5 2 1 1 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) Trimer_CC PF08954.11 EKX46729.1 - 1.8 8.2 12.6 6.1 6.5 0.7 3.8 3 1 0 3 3 3 0 Trimerisation motif Nup88 PF10168.9 EKX46729.1 - 1.9 6.2 12.9 11 3.7 13.3 1.7 1 1 0 1 1 1 0 Nuclear pore component OmpH PF03938.14 EKX46729.1 - 2.1 8.7 17.3 2.2 8.6 9.5 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF4140 PF13600.6 EKX46729.1 - 2.3 8.7 7.2 61 4.1 0.2 3.7 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) FAM76 PF16046.5 EKX46729.1 - 2.6 7.3 13.6 4.6 6.5 13.6 1.3 1 0 0 1 1 1 0 FAM76 protein PRKG1_interact PF15898.5 EKX46729.1 - 2.8 8.9 16.3 14 6.7 7.6 3.0 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain MbeB_N PF04837.12 EKX46729.1 - 3.1 8.2 10.3 8.5 6.8 0.2 3.6 4 0 0 4 4 2 0 MbeB-like, N-term conserved region GBP_C PF02841.14 EKX46729.1 - 3.1 7.1 18.0 14 5.0 18.0 1.8 1 1 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Tup_N PF08581.10 EKX46729.1 - 3.4 8.1 18.0 24 5.3 8.1 3.6 1 1 1 2 2 2 0 Tup N-terminal GrpE PF01025.19 EKX46729.1 - 3.4 7.3 14.5 1e+03 -0.8 14.4 2.8 1 1 0 1 1 1 0 GrpE Sec34 PF04136.15 EKX46729.1 - 3.6 7.5 10.5 12 5.8 2.4 3.2 2 1 0 3 3 2 0 Sec34-like family DUF4446 PF14584.6 EKX46729.1 - 3.6 7.6 12.9 14 5.6 0.7 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Macoilin PF09726.9 EKX46729.1 - 3.7 6.0 17.3 5.9 5.3 7.1 2.1 1 1 1 2 2 2 0 Macoilin family Hemagglutinin PF00509.18 EKX46729.1 - 3.7 5.8 7.3 5.1 5.4 2.0 2.0 1 1 0 1 1 1 0 Haemagglutinin DUF5320 PF17253.2 EKX46729.1 - 4 8.6 11.5 12 7.0 0.7 3.5 1 1 2 3 3 3 0 Family of unknown function (DUF5320) PspB PF06667.12 EKX46729.1 - 4.3 7.5 7.5 22 5.2 0.7 3.4 1 1 2 3 3 3 0 Phage shock protein B TSNAXIP1_N PF15739.5 EKX46729.1 - 4.5 7.7 10.9 14 6.1 3.2 2.7 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus DUF745 PF05335.13 EKX46729.1 - 4.5 7.0 7.6 14 5.4 7.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF745) EMP24_GP25L PF01105.24 EKX46729.1 - 4.7 7.1 11.5 5.2e+03 -2.8 11.6 3.3 1 1 0 1 1 0 0 emp24/gp25L/p24 family/GOLD Cnn_1N PF07989.11 EKX46729.1 - 4.9 7.4 19.0 3.3 7.9 6.5 3.5 2 1 1 3 3 2 0 Centrosomin N-terminal motif 1 HAUS6_N PF14661.6 EKX46729.1 - 5.4 6.5 9.7 13 5.3 9.6 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DMPK_coil PF08826.10 EKX46729.1 - 5.5 7.2 15.5 4.3 7.5 2.1 3.3 1 1 2 3 3 3 0 DMPK coiled coil domain like Fmp27_WPPW PF10359.9 EKX46729.1 - 5.5 5.7 12.5 0.98 8.2 3.5 1.9 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Tho2 PF11262.8 EKX46729.1 - 5.8 6.0 9.8 7.6 5.6 7.3 2.0 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 ACCA PF03255.14 EKX46729.1 - 7.4 6.4 12.0 6.1 6.7 1.5 3.0 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit GARP PF16731.5 EKX46729.1 - 7.4 6.2 7.2 46 3.6 0.2 3.2 1 1 2 3 3 3 0 Glutamic acid/alanine-rich protein of Trypanosoma DUF2968 PF11180.8 EKX46729.1 - 7.6 6.1 10.4 12 5.4 5.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF2408 PF10303.9 EKX46729.1 - 7.7 7.1 10.9 70 4.0 10.9 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) ApoC-I PF04691.12 EKX46729.1 - 8 6.5 9.8 0.73 9.8 0.5 3.6 3 2 0 3 3 2 0 Apolipoprotein C-I (ApoC-1) DUF1515 PF07439.11 EKX46729.1 - 9 6.4 10.2 20 5.2 2.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DUF5082 PF16888.5 EKX46730.1 - 0.0092 16.3 1.0 0.0092 16.3 1.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) TMPIT PF07851.13 EKX46730.1 - 0.013 14.7 2.4 0.015 14.5 2.4 1.0 1 0 0 1 1 1 0 TMPIT-like protein Gp58 PF07902.11 EKX46730.1 - 0.017 13.4 0.3 0.017 13.4 0.3 1.1 1 0 0 1 1 1 0 gp58-like protein T2SSM PF04612.12 EKX46730.1 - 0.019 15.0 2.8 0.03 14.4 2.9 1.3 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein M Cluap1 PF10234.9 EKX46730.1 - 0.024 14.1 1.6 0.024 14.1 1.6 1.5 2 0 0 2 2 2 0 Clusterin-associated protein-1 Atg14 PF10186.9 EKX46730.1 - 0.027 13.6 7.2 0.032 13.3 7.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc24 PF08286.11 EKX46730.1 - 0.041 14.1 1.0 0.046 14.0 1.0 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 FliD_N PF02465.18 EKX46730.1 - 0.043 14.5 1.2 0.053 14.2 1.2 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus DUF4407 PF14362.6 EKX46730.1 - 0.049 13.0 3.5 0.05 13.0 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 EKX46730.1 - 0.049 14.0 4.4 0.06 13.7 4.4 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) kleA_kleC PF17383.2 EKX46730.1 - 0.096 13.0 1.6 0.97 9.8 0.5 2.1 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A CLZ PF16526.5 EKX46730.1 - 0.1 12.9 4.7 0.082 13.3 1.7 2.0 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF641 PF04859.12 EKX46730.1 - 0.11 12.8 4.9 1.3 9.3 1.5 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) SlyX PF04102.12 EKX46730.1 - 0.13 12.9 0.5 0.13 12.9 0.5 1.9 2 1 0 2 2 2 0 SlyX Spectrin PF00435.21 EKX46730.1 - 0.13 12.7 3.6 0.11 13.0 1.7 1.7 1 1 0 1 1 1 0 Spectrin repeat FliJ PF02050.16 EKX46730.1 - 0.14 12.4 6.0 0.1 12.8 4.3 1.6 1 1 1 2 2 2 0 Flagellar FliJ protein GIT_CC PF16559.5 EKX46730.1 - 0.21 11.5 5.0 4.3 7.3 2.4 2.4 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor ubiquitin PF00240.23 EKX46730.1 - 0.24 11.2 2.7 15 5.4 0.0 2.4 2 1 0 2 2 2 0 Ubiquitin family Csm1_N PF18504.1 EKX46730.1 - 0.3 11.4 6.6 0.11 12.8 2.9 1.9 2 0 0 2 2 2 0 Csm1 N-terminal domain Spc7 PF08317.11 EKX46730.1 - 0.32 9.8 6.5 0.17 10.7 4.3 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4140 PF13600.6 EKX46730.1 - 0.41 11.1 5.0 0.25 11.8 2.1 1.9 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 EKX46730.1 - 0.49 10.2 6.7 0.089 12.6 2.9 1.6 2 0 0 2 2 2 0 Septum formation initiator Syntaxin-6_N PF09177.11 EKX46732.1 - 0.019 15.5 0.7 0.14 12.7 0.2 2.5 2 1 1 3 3 2 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 EKX46732.1 - 0.023 14.7 2.2 0.058 13.4 2.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Macoilin PF09726.9 EKX46732.1 - 0.032 12.8 0.4 0.031 12.9 0.4 1.2 1 0 0 1 1 1 0 Macoilin family DUF16 PF01519.16 EKX46732.1 - 0.044 14.3 2.1 0.19 12.2 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 FlaC_arch PF05377.11 EKX46732.1 - 0.045 14.1 2.8 0.063 13.7 0.3 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) ZapB PF06005.12 EKX46732.1 - 0.073 13.5 2.8 0.18 12.3 0.5 2.3 2 0 0 2 2 2 0 Cell division protein ZapB ApoC-I PF04691.12 EKX46732.1 - 0.08 12.9 0.2 0.08 12.9 0.2 3.0 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) DivIC PF04977.15 EKX46732.1 - 0.11 12.3 0.3 0.36 10.6 0.2 1.9 2 0 0 2 2 2 0 Septum formation initiator DASH_Dam1 PF08653.10 EKX46732.1 - 0.11 12.4 0.0 0.35 10.7 0.0 2.0 1 0 0 1 1 1 0 DASH complex subunit Dam1 DUF4618 PF15397.6 EKX46732.1 - 0.11 11.9 2.4 0.2 11.1 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF948 PF06103.11 EKX46732.1 - 0.18 12.1 0.4 0.45 10.8 0.4 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 EKX46732.1 - 0.23 11.8 2.9 0.2 12.0 1.0 1.9 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 EKX46732.1 - 0.27 11.4 1.7 0.28 11.4 0.4 1.7 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family PfUIS3 PF11567.8 EKX46732.1 - 0.36 11.2 2.3 14 6.1 0.0 3.2 2 2 1 3 3 3 0 Plasmodium falciparum UIS3 membrane protein YabA PF06156.13 EKX46732.1 - 0.71 10.5 4.2 3.1 8.5 4.2 2.1 1 1 0 1 1 1 0 Initiation control protein YabA Occludin_ELL PF07303.13 EKX46732.1 - 1.1 10.1 5.0 1.4 9.7 0.9 3.0 3 1 0 3 3 3 0 Occludin homology domain Lebercilin PF15619.6 EKX46732.1 - 4 7.0 8.3 0.65 9.6 3.0 2.2 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DASH_Dam1 PF08653.10 EKX46733.1 - 1.3e-07 31.3 0.5 0.014 15.2 0.1 3.3 1 1 2 3 3 3 2 DASH complex subunit Dam1 PI3K_P85_iSH2 PF16454.5 EKX46733.1 - 5.5e-07 29.3 7.3 0.0006 19.5 0.4 2.2 1 1 1 2 2 2 2 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Syntaxin-6_N PF09177.11 EKX46733.1 - 3.3e-06 27.6 2.9 0.019 15.5 1.8 2.4 1 1 1 2 2 2 2 Syntaxin 6, N-terminal Spc7 PF08317.11 EKX46733.1 - 9.5e-06 24.7 4.4 1.3e-05 24.2 4.4 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 EKX46733.1 - 1.8e-05 24.8 5.0 0.00027 21.0 4.0 2.3 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.21 EKX46733.1 - 2.4e-05 24.3 8.9 0.0019 18.3 0.7 2.7 2 1 1 3 3 2 2 bZIP transcription factor Csm1_N PF18504.1 EKX46733.1 - 6.6e-05 23.2 8.6 0.23 11.8 0.2 3.5 1 1 2 3 3 3 2 Csm1 N-terminal domain FlaC_arch PF05377.11 EKX46733.1 - 7.3e-05 23.1 8.0 0.018 15.5 1.1 3.2 1 1 2 3 3 2 1 Flagella accessory protein C (FlaC) Gp58 PF07902.11 EKX46733.1 - 7.3e-05 21.3 0.3 0.00012 20.6 0.3 1.3 1 1 0 1 1 1 1 gp58-like protein Fib_alpha PF08702.10 EKX46733.1 - 7.8e-05 22.9 5.0 0.00011 22.4 5.0 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family HOOK PF05622.12 EKX46733.1 - 8.2e-05 21.0 8.0 0.00014 20.2 8.0 1.2 1 0 0 1 1 1 1 HOOK protein Lectin_N PF03954.14 EKX46733.1 - 0.0001 22.0 4.9 0.0002 21.1 2.3 2.0 1 1 1 2 2 2 1 Hepatic lectin, N-terminal domain DUF1664 PF07889.12 EKX46733.1 - 0.00014 21.9 8.0 0.00074 19.5 6.5 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) PspA_IM30 PF04012.12 EKX46733.1 - 0.00016 21.3 6.7 0.011 15.3 0.6 2.2 1 1 1 2 2 2 1 PspA/IM30 family NPV_P10 PF05531.12 EKX46733.1 - 0.00016 22.0 5.7 0.091 13.2 0.7 2.3 1 1 0 2 2 2 2 Nucleopolyhedrovirus P10 protein GAS PF13851.6 EKX46733.1 - 0.00018 21.0 7.4 0.00025 20.5 7.4 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.9 EKX46733.1 - 0.00018 21.7 8.3 0.0061 16.8 0.8 2.2 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 ZapB PF06005.12 EKX46733.1 - 0.00019 21.8 9.7 0.018 15.4 0.3 2.7 1 1 1 2 2 2 1 Cell division protein ZapB AIP3 PF03915.13 EKX46733.1 - 0.00019 20.7 2.6 0.00021 20.5 2.6 1.0 1 0 0 1 1 1 1 Actin interacting protein 3 Vps51 PF08700.11 EKX46733.1 - 0.00023 21.2 5.3 0.16 12.1 0.4 2.9 2 1 0 2 2 2 2 Vps51/Vps67 Seryl_tRNA_N PF02403.22 EKX46733.1 - 0.00025 21.3 10.9 0.062 13.5 10.9 2.5 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain CCDC144C PF14915.6 EKX46733.1 - 0.00025 20.3 6.2 0.0004 19.6 6.2 1.3 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region UPF0242 PF06785.11 EKX46733.1 - 0.00027 21.1 3.5 0.00034 20.8 3.5 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus FapA PF03961.13 EKX46733.1 - 0.00028 19.6 1.1 0.00029 19.6 1.1 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A DUF677 PF05055.12 EKX46733.1 - 0.00033 19.7 2.0 0.00042 19.3 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF677) DUF4618 PF15397.6 EKX46733.1 - 0.00034 20.1 7.8 0.0021 17.6 7.8 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4618) DivIC PF04977.15 EKX46733.1 - 0.00044 20.0 4.8 0.059 13.1 0.2 2.5 2 1 0 2 2 2 1 Septum formation initiator Filament PF00038.21 EKX46733.1 - 0.00047 19.8 8.0 0.00064 19.4 6.7 1.7 1 1 1 2 2 2 2 Intermediate filament protein YscO PF07321.12 EKX46733.1 - 0.00051 20.0 4.2 0.0011 18.9 4.2 1.6 1 1 0 1 1 1 1 Type III secretion protein YscO IFT57 PF10498.9 EKX46733.1 - 0.00081 18.5 6.3 0.001 18.1 6.3 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DUF3972 PF13118.6 EKX46733.1 - 0.00088 19.7 6.7 0.0018 18.7 6.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3972) Med9 PF07544.13 EKX46733.1 - 0.0009 19.3 6.2 0.0014 18.7 4.4 2.1 1 1 1 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Lebercilin PF15619.6 EKX46733.1 - 0.00093 18.9 8.5 0.0014 18.4 8.5 1.3 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease HMMR_N PF15905.5 EKX46733.1 - 0.001 18.7 8.2 0.0014 18.1 8.2 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Rab5-bind PF09311.11 EKX46733.1 - 0.001 18.5 6.0 0.0014 18.1 6.0 1.1 1 0 0 1 1 1 1 Rabaptin-like protein LXG PF04740.12 EKX46733.1 - 0.0011 18.7 2.5 0.47 10.1 0.1 2.2 1 1 1 2 2 2 1 LXG domain of WXG superfamily FmiP_Thoc5 PF09766.9 EKX46733.1 - 0.0015 17.9 6.5 0.034 13.5 3.0 2.0 1 1 1 2 2 2 1 Fms-interacting protein/Thoc5 Trimer_CC PF08954.11 EKX46733.1 - 0.0016 18.0 2.4 1 9.0 0.1 2.5 2 1 0 2 2 2 0 Trimerisation motif AAA_32 PF13654.6 EKX46733.1 - 0.0019 17.1 3.3 0.0024 16.8 3.3 1.1 1 0 0 1 1 1 1 AAA domain HALZ PF02183.18 EKX46733.1 - 0.0022 18.2 5.2 0.37 11.1 0.1 3.6 2 2 1 3 3 3 1 Homeobox associated leucine zipper Helo_like_N PF17111.5 EKX46733.1 - 0.0023 17.4 1.8 0.24 10.8 0.1 2.2 1 1 1 2 2 2 1 Fungal N-terminal domain of STAND proteins Baculo_PEP_C PF04513.12 EKX46733.1 - 0.0023 18.0 0.1 0.0031 17.6 0.1 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4200 PF13863.6 EKX46733.1 - 0.0023 18.3 9.7 0.29 11.5 3.5 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4200) Laminin_II PF06009.12 EKX46733.1 - 0.0024 17.9 5.2 0.076 13.0 0.7 2.1 1 1 1 2 2 2 1 Laminin Domain II Fez1 PF06818.15 EKX46733.1 - 0.0025 18.3 6.8 0.0038 17.7 6.8 1.2 1 0 0 1 1 1 1 Fez1 DUF16 PF01519.16 EKX46733.1 - 0.0025 18.3 10.1 0.029 14.8 1.4 2.1 1 1 1 2 2 2 1 Protein of unknown function DUF16 TACC_C PF05010.14 EKX46733.1 - 0.0029 17.4 8.8 0.0069 16.2 8.8 1.6 1 1 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal WXG100 PF06013.12 EKX46733.1 - 0.003 17.8 2.5 1.7 9.0 0.2 2.7 1 1 1 2 2 2 0 Proteins of 100 residues with WXG AKNA PF12443.8 EKX46733.1 - 0.0032 18.1 8.9 0.23 12.1 1.0 3.0 1 1 1 2 2 2 1 AT-hook-containing transcription factor Golgin_A5 PF09787.9 EKX46733.1 - 0.0034 16.9 7.3 0.0046 16.5 7.3 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 LPP PF04728.13 EKX46733.1 - 0.0034 17.7 2.3 4.6 7.7 0.2 3.2 2 1 0 2 2 2 0 Lipoprotein leucine-zipper DUF3584 PF12128.8 EKX46733.1 - 0.0037 14.9 5.1 0.0051 14.4 5.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Prefoldin PF02996.17 EKX46733.1 - 0.0039 17.1 5.5 0.81 9.6 0.8 2.6 1 1 0 2 2 2 1 Prefoldin subunit THOC7 PF05615.13 EKX46733.1 - 0.004 17.4 5.7 0.47 10.7 1.6 2.3 1 1 1 2 2 2 1 Tho complex subunit 7 Prominin PF05478.11 EKX46733.1 - 0.0041 15.2 4.5 0.0082 14.2 4.4 1.4 1 1 0 1 1 1 1 Prominin DUF948 PF06103.11 EKX46733.1 - 0.0042 17.3 5.7 0.37 11.1 5.7 2.5 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) WEMBL PF05701.11 EKX46733.1 - 0.0043 15.8 3.5 0.0055 15.5 3.5 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light SKA2 PF16740.5 EKX46733.1 - 0.0045 16.8 6.0 0.014 15.2 3.7 2.1 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 2 YkyA PF10368.9 EKX46733.1 - 0.0047 16.6 9.7 0.013 15.1 9.7 1.6 1 1 0 1 1 1 1 Putative cell-wall binding lipoprotein Tropomyosin_1 PF12718.7 EKX46733.1 - 0.0047 17.1 12.4 0.009 16.2 12.4 1.4 1 0 0 1 1 1 1 Tropomyosin like Macoilin PF09726.9 EKX46733.1 - 0.005 15.5 2.1 0.0069 15.0 2.1 1.3 1 0 0 1 1 1 1 Macoilin family Spectrin PF00435.21 EKX46733.1 - 0.0058 17.1 8.5 0.05 14.1 8.5 2.2 1 1 0 1 1 1 1 Spectrin repeat Bacillus_HBL PF05791.11 EKX46733.1 - 0.006 16.4 4.6 0.0091 15.8 4.6 1.4 1 1 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) Exonuc_VII_L PF02601.15 EKX46733.1 - 0.006 16.2 0.4 0.0067 16.0 0.4 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit DUF3450 PF11932.8 EKX46733.1 - 0.006 15.9 6.9 0.034 13.5 1.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) SlyX PF04102.12 EKX46733.1 - 0.0064 17.1 6.9 1.6 9.4 0.5 3.3 1 1 2 3 3 3 0 SlyX ApoLp-III PF07464.11 EKX46733.1 - 0.0065 16.6 3.9 0.01 15.9 3.9 1.4 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) EzrA PF06160.12 EKX46733.1 - 0.0066 14.7 8.0 0.021 13.0 8.0 1.3 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA CK2S PF15011.6 EKX46733.1 - 0.0067 16.3 4.3 0.56 10.1 0.3 2.4 1 1 1 2 2 2 1 Casein Kinase 2 substrate Apolipoprotein PF01442.18 EKX46733.1 - 0.0079 16.1 4.5 0.014 15.3 4.5 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF4988 PF16378.5 EKX46733.1 - 0.0081 15.8 2.6 0.53 9.9 0.3 2.3 1 1 1 2 2 2 1 Domain of unknown function CALCOCO1 PF07888.11 EKX46733.1 - 0.0082 15.1 5.5 0.013 14.4 5.5 1.3 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Prefoldin_2 PF01920.20 EKX46733.1 - 0.0087 16.0 13.5 0.16 11.9 3.6 2.8 1 1 2 3 3 3 1 Prefoldin subunit Allexi_40kDa PF05549.11 EKX46733.1 - 0.0089 15.6 1.5 0.013 15.1 1.5 1.3 1 0 0 1 1 1 1 Allexivirus 40kDa protein Cast PF10174.9 EKX46733.1 - 0.0091 14.3 7.4 0.011 14.0 7.4 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone AAA_13 PF13166.6 EKX46733.1 - 0.0096 14.6 1.7 0.013 14.2 1.7 1.1 1 0 0 1 1 1 1 AAA domain Mod_r PF07200.13 EKX46733.1 - 0.0096 16.0 6.1 1.6 8.8 2.8 2.1 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein TelA PF05816.11 EKX46733.1 - 0.01 15.0 4.0 0.013 14.6 4.0 1.1 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) DUF724 PF05266.14 EKX46733.1 - 0.012 15.5 8.4 0.078 12.8 8.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF724) TMPIT PF07851.13 EKX46733.1 - 0.012 14.9 2.4 0.018 14.3 2.4 1.3 1 0 0 1 1 1 0 TMPIT-like protein CENP-K PF11802.8 EKX46733.1 - 0.013 15.1 2.5 0.016 14.8 2.5 1.2 1 0 0 1 1 1 0 Centromere-associated protein K Occludin_ELL PF07303.13 EKX46733.1 - 0.013 16.2 3.8 0.11 13.2 2.7 2.4 1 1 1 2 2 2 0 Occludin homology domain YabA PF06156.13 EKX46733.1 - 0.014 16.0 8.3 0.21 12.3 8.2 2.4 1 1 0 1 1 1 0 Initiation control protein YabA AP_endonuc_2_N PF07582.12 EKX46733.1 - 0.015 15.0 0.1 4.5 7.1 0.0 2.9 2 1 0 2 2 2 0 AP endonuclease family 2 C terminus HemX PF04375.14 EKX46733.1 - 0.018 14.4 2.7 0.028 13.7 2.7 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase SYCE1 PF15233.6 EKX46733.1 - 0.02 15.0 2.4 0.02 15.0 2.4 2.0 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 Phage_GP20 PF06810.11 EKX46733.1 - 0.02 14.7 14.5 0.85 9.4 3.2 3.0 1 1 2 3 3 3 0 Phage minor structural protein GP20 DASH_Duo1 PF08651.10 EKX46733.1 - 0.021 14.6 0.8 9.3 6.1 0.1 3.1 1 1 2 3 3 3 0 DASH complex subunit Duo1 FAM76 PF16046.5 EKX46733.1 - 0.022 14.1 2.3 0.026 13.9 2.3 1.1 1 0 0 1 1 1 0 FAM76 protein HIP1_clath_bdg PF16515.5 EKX46733.1 - 0.022 15.3 12.2 0.053 14.1 3.2 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 HrpB7 PF09486.10 EKX46733.1 - 0.024 15.1 2.1 0.055 13.9 2.1 1.6 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF4201 PF13870.6 EKX46733.1 - 0.025 14.3 9.8 0.037 13.8 9.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) TSC22 PF01166.18 EKX46733.1 - 0.025 14.9 5.3 4.3 7.7 2.1 3.5 1 1 1 2 2 2 0 TSC-22/dip/bun family Cytochrom_B562 PF07361.11 EKX46733.1 - 0.026 15.2 8.1 0.88 10.3 6.1 2.2 1 1 1 2 2 2 0 Cytochrome b562 DUF4407 PF14362.6 EKX46733.1 - 0.027 13.8 4.3 0.11 11.8 4.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 EKX46733.1 - 0.027 14.5 7.1 0.091 12.8 4.0 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF812 PF05667.11 EKX46733.1 - 0.029 13.3 11.9 0.093 11.6 11.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) APG17 PF04108.12 EKX46733.1 - 0.029 13.5 3.2 0.043 12.9 2.1 1.6 1 1 1 2 2 2 0 Autophagy protein Apg17 DUF5082 PF16888.5 EKX46733.1 - 0.032 14.5 3.7 0.059 13.6 3.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) V-SNARE_C PF12352.8 EKX46733.1 - 0.034 14.4 1.0 1.2 9.5 0.1 2.3 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus GrpE PF01025.19 EKX46733.1 - 0.034 13.8 8.3 0.36 10.5 8.4 2.0 1 1 0 1 1 1 0 GrpE CorA PF01544.18 EKX46733.1 - 0.034 13.5 1.4 0.045 13.1 1.4 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein LOH1CR12 PF10158.9 EKX46733.1 - 0.037 14.1 0.9 0.12 12.4 0.2 1.8 1 1 1 2 2 2 0 Tumour suppressor protein MbeD_MobD PF04899.12 EKX46733.1 - 0.038 14.1 1.2 3 8.0 0.3 2.7 1 1 1 2 2 2 0 MbeD/MobD like Jnk-SapK_ap_N PF09744.9 EKX46733.1 - 0.038 14.2 7.5 0.065 13.5 7.5 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Lambda_tail_I PF06805.12 EKX46733.1 - 0.039 14.3 0.1 4.7 7.6 0.0 2.7 1 1 1 2 2 2 0 Bacteriophage lambda tail assembly protein I TMF_DNA_bd PF12329.8 EKX46733.1 - 0.041 13.9 12.8 0.4 10.7 2.0 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding V_ATPase_I PF01496.19 EKX46733.1 - 0.042 11.8 2.7 0.052 11.5 2.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Muted PF14942.6 EKX46733.1 - 0.043 14.2 8.6 0.21 11.9 8.6 1.9 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein Sec34 PF04136.15 EKX46733.1 - 0.05 13.5 2.6 1.2 9.0 2.6 2.1 1 1 0 1 1 1 0 Sec34-like family Snapin_Pallidin PF14712.6 EKX46733.1 - 0.05 14.0 7.8 0.043 14.2 3.0 2.4 1 1 2 3 3 3 0 Snapin/Pallidin KxDL PF10241.9 EKX46733.1 - 0.05 13.9 6.4 1.2 9.5 1.7 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein HlyD_2 PF12700.7 EKX46733.1 - 0.052 12.3 4.5 0.064 12.0 4.5 1.1 1 0 0 1 1 1 0 HlyD family secretion protein Nmad5 PF18757.1 EKX46733.1 - 0.053 13.7 4.0 0.35 11.0 4.0 2.4 1 1 0 1 1 1 0 Nucleotide modification associated domain 5 Atg14 PF10186.9 EKX46733.1 - 0.054 12.6 1.3 0.095 11.8 1.3 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Nup88 PF10168.9 EKX46733.1 - 0.054 11.3 5.0 0.07 10.9 5.0 1.2 1 0 0 1 1 1 0 Nuclear pore component Prefoldin_3 PF13758.6 EKX46733.1 - 0.055 13.5 4.2 0.12 12.5 4.1 1.7 1 1 0 1 1 1 0 Prefoldin subunit Tektin PF03148.14 EKX46733.1 - 0.057 12.2 8.9 0.1 11.4 8.9 1.3 1 0 0 1 1 1 0 Tektin family CENP-F_leu_zip PF10473.9 EKX46733.1 - 0.059 13.4 13.1 0.088 12.8 10.5 2.1 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4446 PF14584.6 EKX46733.1 - 0.062 13.3 5.9 1.6 8.7 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) SKA1 PF07160.12 EKX46733.1 - 0.062 13.1 5.9 1.4 8.7 0.2 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Spc29 PF17082.5 EKX46733.1 - 0.066 13.0 2.9 0.2 11.5 3.0 1.6 1 1 0 1 1 1 0 Spindle Pole Component 29 Gp-FAR-1 PF05823.12 EKX46733.1 - 0.067 13.5 6.5 1.2 9.5 0.7 2.8 1 1 2 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) CEP63 PF17045.5 EKX46733.1 - 0.068 13.1 7.1 0.11 12.4 7.1 1.4 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa T3SSipB PF16535.5 EKX46733.1 - 0.074 13.5 2.9 0.49 10.9 1.7 2.0 1 1 1 2 2 2 0 Type III cell invasion protein SipB DUF2730 PF10805.8 EKX46733.1 - 0.074 13.1 7.3 2.3 8.4 1.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Phage_GPO PF05929.11 EKX46733.1 - 0.078 12.6 5.4 0.15 11.7 5.4 1.5 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase MCPsignal PF00015.21 EKX46733.1 - 0.078 12.8 0.6 0.11 12.3 0.6 1.2 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Fzo_mitofusin PF04799.13 EKX46733.1 - 0.082 12.4 6.7 0.84 9.2 2.3 2.7 1 1 2 3 3 3 0 fzo-like conserved region Ax_dynein_light PF10211.9 EKX46733.1 - 0.093 12.7 11.9 0.09 12.7 8.3 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain KfrA_N PF11740.8 EKX46733.1 - 0.094 13.4 1.2 2.1 9.1 1.2 2.5 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term Syntaxin PF00804.25 EKX46733.1 - 0.096 12.4 7.5 2.8 7.6 1.0 2.3 1 1 1 2 2 2 0 Syntaxin Dabb PF07876.12 EKX46733.1 - 0.096 13.3 2.6 9.3 7.0 0.3 2.4 1 1 1 2 2 2 0 Stress responsive A/B Barrel Domain Alpha-E PF04168.12 EKX46733.1 - 0.11 12.3 0.3 0.52 10.0 0.3 1.8 1 1 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. Sec20 PF03908.13 EKX46733.1 - 0.11 12.5 1.3 0.97 9.4 0.4 2.1 1 1 1 2 2 2 0 Sec20 RmuC PF02646.16 EKX46733.1 - 0.13 11.4 8.2 0.21 10.7 3.9 2.2 1 1 1 2 2 2 0 RmuC family VraX PF17412.2 EKX46733.1 - 0.14 11.8 0.0 11 5.7 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function YtxH PF12732.7 EKX46733.1 - 0.14 12.7 6.8 33 5.1 6.8 2.5 1 1 0 1 1 1 0 YtxH-like protein HAP1_N PF04849.13 EKX46733.1 - 0.14 11.3 8.9 0.24 10.6 8.9 1.4 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Spc24 PF08286.11 EKX46733.1 - 0.15 12.3 7.6 2 8.7 4.3 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 IFT20 PF14931.6 EKX46733.1 - 0.15 12.2 7.1 3.3 7.9 0.5 2.1 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 Fmp27_WPPW PF10359.9 EKX46733.1 - 0.15 10.9 4.8 0.21 10.4 4.8 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain ORF6C PF10552.9 EKX46733.1 - 0.15 12.1 7.7 2.5 8.2 0.7 2.9 1 1 2 3 3 2 0 ORF6C domain HalX PF08663.10 EKX46733.1 - 0.16 12.3 1.8 3.4 8.0 0.2 3.0 1 1 1 2 2 2 0 HalX domain DUF4140 PF13600.6 EKX46733.1 - 0.16 12.4 2.3 13 6.3 2.3 2.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF5320 PF17253.2 EKX46733.1 - 0.17 13.0 5.2 3.4 8.8 0.3 2.8 1 1 1 2 2 2 0 Family of unknown function (DUF5320) Tmemb_cc2 PF10267.9 EKX46733.1 - 0.18 10.9 10.1 0.75 8.9 10.5 1.6 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Sulfatase_C PF14707.6 EKX46733.1 - 0.21 12.3 1.5 27 5.5 0.0 2.2 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase DASH_Dad2 PF08654.10 EKX46733.1 - 0.24 11.8 6.4 3.6 8.1 0.8 2.4 1 1 1 2 2 2 0 DASH complex subunit Dad2 Fungal_TACC PF12709.7 EKX46733.1 - 0.25 11.8 8.4 1.6 9.3 0.9 2.4 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins SpecificRecomb PF10136.9 EKX46733.1 - 0.28 9.4 1.2 0.87 7.8 1.2 1.6 1 1 0 1 1 1 0 Site-specific recombinase End3 PF12761.7 EKX46733.1 - 0.28 11.3 8.9 4 7.6 2.1 2.1 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Rootletin PF15035.6 EKX46733.1 - 0.29 11.2 8.0 0.61 10.1 5.8 1.9 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion USP8_interact PF08941.10 EKX46733.1 - 0.29 10.9 4.4 1.1 9.1 0.4 2.1 1 1 1 2 2 2 0 USP8 interacting ACCA PF03255.14 EKX46733.1 - 0.29 11.0 6.9 1.6 8.6 1.3 2.2 1 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit MAD PF05557.13 EKX46733.1 - 0.31 9.3 10.6 0.58 8.5 10.6 1.4 1 1 0 1 1 1 0 Mitotic checkpoint protein Laminin_I PF06008.14 EKX46733.1 - 0.32 10.7 8.7 3.2 7.4 8.8 2.0 1 1 0 1 1 1 0 Laminin Domain I CAF-1_p150 PF11600.8 EKX46733.1 - 0.32 10.7 9.1 0.46 10.2 9.1 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CLZ PF16526.5 EKX46733.1 - 0.33 11.3 11.9 2.9 8.3 1.6 2.4 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels EMP24_GP25L PF01105.24 EKX46733.1 - 0.37 10.7 7.5 9.6 6.1 1.5 2.3 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD XhlA PF10779.9 EKX46733.1 - 0.37 11.0 14.6 2.3 8.5 4.3 3.3 1 1 2 3 3 3 0 Haemolysin XhlA CREPT PF16566.5 EKX46733.1 - 0.4 10.8 5.9 5.3 7.2 5.9 2.0 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Tup_N PF08581.10 EKX46733.1 - 0.43 10.9 11.4 11 6.4 0.7 3.1 1 1 2 3 3 3 0 Tup N-terminal DUF4455 PF14643.6 EKX46733.1 - 0.51 8.9 8.2 0.95 8.0 8.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4455) BRE1 PF08647.11 EKX46733.1 - 0.52 10.4 8.7 1.8 8.7 8.7 1.8 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase 5_nucleotid PF05761.14 EKX46733.1 - 0.53 9.1 5.1 0.5 9.2 0.3 2.0 1 1 1 2 2 2 0 5' nucleotidase family DUF745 PF05335.13 EKX46733.1 - 0.53 10.0 3.4 1.2 8.9 1.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF745) YjfB_motility PF14070.6 EKX46733.1 - 0.75 10.0 4.3 9.9 6.4 0.4 2.4 2 0 0 2 2 2 0 Putative motility protein TMF_TATA_bd PF12325.8 EKX46733.1 - 0.82 9.9 13.1 4 7.7 13.4 1.9 1 1 1 2 2 1 0 TATA element modulatory factor 1 TATA binding Cnn_1N PF07989.11 EKX46733.1 - 0.83 9.9 12.4 1.9 8.7 0.6 2.3 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 ApoC-I PF04691.12 EKX46733.1 - 0.84 9.6 5.1 2.4 8.2 0.8 3.2 1 1 2 3 3 3 0 Apolipoprotein C-I (ApoC-1) APG6_N PF17675.1 EKX46733.1 - 0.86 10.1 9.6 0.51 10.9 5.4 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region CENP-H PF05837.12 EKX46733.1 - 0.89 10.0 7.0 6 7.3 7.0 2.1 1 1 0 1 1 1 0 Centromere protein H (CENP-H) UPF0449 PF15136.6 EKX46733.1 - 0.94 10.0 5.8 87 3.7 6.0 2.6 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 OmpH PF03938.14 EKX46733.1 - 1.2 9.5 10.0 3.5 7.9 8.7 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF641 PF04859.12 EKX46733.1 - 1.3 9.3 6.9 6.8 7.0 6.9 2.1 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) bZIP_2 PF07716.15 EKX46733.1 - 1.3 9.1 9.0 6.4 6.9 0.0 3.7 1 1 2 3 3 3 0 Basic region leucine zipper CtIP_N PF10482.9 EKX46733.1 - 1.5 8.9 9.2 1.2 9.1 2.2 2.4 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DUF4795 PF16043.5 EKX46733.1 - 2 8.0 13.9 13 5.3 14.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) ATG16 PF08614.11 EKX46733.1 - 2.2 8.5 10.3 20 5.3 10.4 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) PRKG1_interact PF15898.5 EKX46733.1 - 2.5 9.0 10.5 7.8 7.5 7.3 2.5 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DMPK_coil PF08826.10 EKX46733.1 - 2.8 8.1 12.2 1 9.5 2.0 3.0 2 1 1 3 3 2 0 DMPK coiled coil domain like FlxA PF14282.6 EKX46733.1 - 3.4 7.7 8.3 9.1 6.3 1.7 2.3 1 1 2 3 3 3 0 FlxA-like protein DUF4337 PF14235.6 EKX46733.1 - 3.5 7.7 5.0 13 5.8 2.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) DUF1640 PF07798.11 EKX46733.1 - 3.9 7.5 11.3 3.2 7.8 3.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) DUF4559 PF15112.6 EKX46733.1 - 3.9 7.0 10.7 6.5 6.3 10.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) CC2-LZ PF16516.5 EKX46733.1 - 4.5 7.7 10.2 5.5 7.4 1.5 2.4 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator PIEZO PF15917.5 EKX46733.1 - 4.5 6.7 8.5 4.1 6.8 1.4 2.0 1 1 1 2 2 2 0 Piezo Tsc35 PF15079.6 EKX46733.1 - 4.6 6.8 17.7 8.3 5.9 1.8 2.1 1 1 1 2 2 2 0 Testis-specific protein 35 Tho2 PF11262.8 EKX46733.1 - 4.9 6.3 8.0 8.3 5.5 4.1 1.9 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 BST2 PF16716.5 EKX46733.1 - 6.4 7.4 11.9 9.4 6.9 2.6 2.8 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 DUF3782 PF12644.7 EKX46733.1 - 6.8 6.9 9.0 20 5.4 0.9 3.2 2 1 2 4 4 3 0 Protein of unknown function (DUF3782) Rbsn PF11464.8 EKX46733.1 - 9 6.1 10.9 7.2 6.4 0.1 3.4 4 0 0 4 4 2 0 Rabenosyn Rab binding domain Gp58 PF07902.11 EKX46734.1 - 0.0063 14.9 0.5 0.0063 14.9 0.5 1.0 1 0 0 1 1 1 1 gp58-like protein DUF5082 PF16888.5 EKX46734.1 - 0.0092 16.3 1.0 0.0092 16.3 1.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) TMPIT PF07851.13 EKX46734.1 - 0.013 14.8 2.3 0.015 14.6 2.3 1.0 1 0 0 1 1 1 0 TMPIT-like protein Cluap1 PF10234.9 EKX46734.1 - 0.024 14.1 1.6 0.024 14.1 1.6 1.5 2 0 0 2 2 2 0 Clusterin-associated protein-1 T2SSM PF04612.12 EKX46734.1 - 0.032 14.3 2.9 0.043 13.9 2.9 1.3 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein M Spc24 PF08286.11 EKX46734.1 - 0.036 14.3 0.9 0.04 14.2 0.9 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF4407 PF14362.6 EKX46734.1 - 0.039 13.3 3.9 0.04 13.3 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 EKX46734.1 - 0.043 12.9 6.7 0.049 12.7 6.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OmpH PF03938.14 EKX46734.1 - 0.043 14.2 4.1 0.052 13.9 4.1 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FliD_N PF02465.18 EKX46734.1 - 0.052 14.2 1.5 0.065 13.9 1.5 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Spectrin PF00435.21 EKX46734.1 - 0.11 13.0 3.4 0.14 12.6 2.5 1.7 1 1 1 2 2 2 0 Spectrin repeat CLZ PF16526.5 EKX46734.1 - 0.11 12.9 4.7 0.082 13.3 1.7 2.0 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF641 PF04859.12 EKX46734.1 - 0.11 12.8 4.8 1.3 9.4 1.4 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) SlyX PF04102.12 EKX46734.1 - 0.12 13.0 0.4 0.12 13.0 0.4 1.9 2 1 0 2 2 2 0 SlyX FliJ PF02050.16 EKX46734.1 - 0.18 12.0 6.1 0.13 12.5 4.3 1.6 1 1 1 2 2 2 0 Flagellar FliJ protein GIT_CC PF16559.5 EKX46734.1 - 0.21 11.5 5.0 4.3 7.3 2.4 2.4 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Csm1_N PF18504.1 EKX46734.1 - 0.21 11.9 6.1 0.11 12.8 2.9 1.9 2 0 0 2 2 2 0 Csm1 N-terminal domain Spc7 PF08317.11 EKX46734.1 - 0.22 10.4 6.0 0.33 9.8 6.0 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein ubiquitin PF00240.23 EKX46734.1 - 0.24 11.2 2.7 15 5.4 0.0 2.4 2 1 0 2 2 2 0 Ubiquitin family DivIC PF04977.15 EKX46734.1 - 0.48 10.2 6.7 0.089 12.6 2.9 1.7 2 0 0 2 2 2 0 Septum formation initiator DUF4140 PF13600.6 EKX46734.1 - 2.9 8.4 7.9 0.96 9.9 3.9 1.9 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) CCDC144C PF14915.6 EKX46736.1 - 1.4e-05 24.3 7.5 2.2e-05 23.7 7.5 1.2 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region GAS PF13851.6 EKX46736.1 - 7e-05 22.3 8.8 0.00044 19.7 8.1 2.1 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding DASH_Dam1 PF08653.10 EKX46736.1 - 0.00016 21.4 0.3 0.35 10.7 0.0 2.8 2 0 0 2 2 2 1 DASH complex subunit Dam1 TACC_C PF05010.14 EKX46736.1 - 0.00021 21.1 7.2 0.00043 20.1 7.2 1.4 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal AIP3 PF03915.13 EKX46736.1 - 0.00042 19.5 0.9 0.0006 19.0 0.9 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 FlaC_arch PF05377.11 EKX46736.1 - 0.001 19.4 6.2 0.043 14.2 0.5 3.1 2 1 1 3 3 2 1 Flagella accessory protein C (FlaC) Spc7 PF08317.11 EKX46736.1 - 0.0012 17.8 5.2 0.0026 16.7 5.2 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein DivIC PF04977.15 EKX46736.1 - 0.0012 18.6 1.6 0.22 11.3 0.2 2.7 2 0 0 2 2 2 1 Septum formation initiator Syntaxin-6_N PF09177.11 EKX46736.1 - 0.0012 19.4 3.2 0.85 10.2 0.9 3.0 2 1 1 3 3 2 2 Syntaxin 6, N-terminal DUF812 PF05667.11 EKX46736.1 - 0.0015 17.5 2.0 0.003 16.5 2.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF812) AAA_32 PF13654.6 EKX46736.1 - 0.0032 16.3 1.2 0.0049 15.7 1.2 1.2 1 0 0 1 1 1 1 AAA domain DUF1664 PF07889.12 EKX46736.1 - 0.0038 17.3 6.0 0.0091 16.0 5.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) Spectrin PF00435.21 EKX46736.1 - 0.0052 17.2 5.2 0.013 16.0 5.2 1.6 1 0 0 1 1 1 1 Spectrin repeat Phage_GPO PF05929.11 EKX46736.1 - 0.0063 16.2 1.7 0.0095 15.6 1.7 1.2 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase FapA PF03961.13 EKX46736.1 - 0.0072 15.0 0.5 0.01 14.5 0.5 1.2 1 0 0 1 1 1 1 Flagellar Assembly Protein A HMMR_N PF15905.5 EKX46736.1 - 0.0077 15.7 5.6 0.0077 15.7 5.6 1.6 2 0 0 2 2 1 1 Hyaluronan mediated motility receptor N-terminal Golgin_A5 PF09787.9 EKX46736.1 - 0.008 15.7 6.1 0.014 14.9 6.1 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 5 Lebercilin PF15619.6 EKX46736.1 - 0.009 15.7 9.7 0.009 15.7 9.7 2.1 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease ZapB PF06005.12 EKX46736.1 - 0.0091 16.4 9.7 0.095 13.2 0.4 2.6 1 1 0 2 2 2 1 Cell division protein ZapB DUF677 PF05055.12 EKX46736.1 - 0.0093 14.9 0.6 0.015 14.2 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF677) DUF3584 PF12128.8 EKX46736.1 - 0.0099 13.5 4.1 0.014 12.9 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Gp58 PF07902.11 EKX46736.1 - 0.01 14.2 0.7 0.039 12.2 0.9 1.7 1 1 1 2 2 2 0 gp58-like protein Lectin_N PF03954.14 EKX46736.1 - 0.012 15.3 4.4 0.13 12.0 0.5 2.3 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain TPR_MLP1_2 PF07926.12 EKX46736.1 - 0.013 15.5 5.9 0.013 15.5 5.9 2.2 2 1 0 2 2 1 0 TPR/MLP1/MLP2-like protein PI3K_P85_iSH2 PF16454.5 EKX46736.1 - 0.014 15.0 7.9 0.29 10.7 0.5 2.5 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Csm1_N PF18504.1 EKX46736.1 - 0.015 15.7 7.8 1 9.8 0.7 3.4 1 1 2 3 3 3 0 Csm1 N-terminal domain BLOC1_2 PF10046.9 EKX46736.1 - 0.021 15.1 9.8 0.19 12.0 0.6 2.6 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AKNA PF12443.8 EKX46736.1 - 0.022 15.4 5.9 1.8 9.2 1.2 2.7 1 1 1 2 2 2 0 AT-hook-containing transcription factor Syntaxin PF00804.25 EKX46736.1 - 0.022 14.4 6.1 0.58 9.8 1.2 2.4 1 1 1 2 2 2 0 Syntaxin DUF4618 PF15397.6 EKX46736.1 - 0.025 14.0 8.2 1.7 8.0 8.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) NPV_P10 PF05531.12 EKX46736.1 - 0.026 15.0 4.8 1 9.9 0.6 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3450 PF11932.8 EKX46736.1 - 0.027 13.8 4.5 0.061 12.6 4.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) UPF0242 PF06785.11 EKX46736.1 - 0.032 14.4 3.5 0.062 13.4 3.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Seryl_tRNA_N PF02403.22 EKX46736.1 - 0.033 14.4 8.3 0.4 10.9 8.3 2.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ABC_tran_CTD PF16326.5 EKX46736.1 - 0.035 14.4 2.4 0.11 12.7 2.4 1.9 1 0 0 1 1 1 0 ABC transporter C-terminal domain Fzo_mitofusin PF04799.13 EKX46736.1 - 0.036 13.6 5.0 0.15 11.6 2.0 2.3 1 1 1 2 2 2 0 fzo-like conserved region Vps51 PF08700.11 EKX46736.1 - 0.036 14.1 7.0 0.95 9.6 0.2 2.9 3 0 0 3 3 2 0 Vps51/Vps67 Exonuc_VII_L PF02601.15 EKX46736.1 - 0.037 13.6 0.2 0.059 12.9 0.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit EzrA PF06160.12 EKX46736.1 - 0.039 12.1 4.5 0.068 11.3 4.5 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA YabA PF06156.13 EKX46736.1 - 0.042 14.5 5.6 0.25 12.0 5.6 2.2 1 1 0 1 1 1 0 Initiation control protein YabA Alpha-E PF04168.12 EKX46736.1 - 0.051 13.4 0.1 0.097 12.4 0.1 1.5 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. Prominin PF05478.11 EKX46736.1 - 0.059 11.3 1.5 0.086 10.8 1.5 1.1 1 0 0 1 1 1 0 Prominin OmpH PF03938.14 EKX46736.1 - 0.059 13.7 3.6 0.15 12.4 3.6 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Rbsn PF11464.8 EKX46736.1 - 0.061 13.1 0.4 17 5.2 0.0 2.9 2 0 0 2 2 2 0 Rabenosyn Rab binding domain Med9 PF07544.13 EKX46736.1 - 0.062 13.4 3.8 0.22 11.7 3.8 2.1 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF948 PF06103.11 EKX46736.1 - 0.072 13.4 3.5 0.31 11.3 3.4 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Tmemb_cc2 PF10267.9 EKX46736.1 - 0.076 12.2 9.0 0.11 11.6 8.4 1.5 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Prefoldin PF02996.17 EKX46736.1 - 0.081 12.8 4.9 1.2 9.1 0.7 2.8 2 1 1 3 3 2 0 Prefoldin subunit PfUIS3 PF11567.8 EKX46736.1 - 0.082 13.3 5.6 16 5.9 0.0 3.5 2 2 2 4 4 4 0 Plasmodium falciparum UIS3 membrane protein Phage_HK97_TLTM PF06120.11 EKX46736.1 - 0.083 12.1 4.9 0.19 10.9 4.9 1.6 1 0 0 1 1 1 0 Tail length tape measure protein Baculo_PEP_C PF04513.12 EKX46736.1 - 0.098 12.7 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus THOC7 PF05615.13 EKX46736.1 - 0.13 12.5 5.8 4.8 7.5 0.4 2.4 1 1 1 2 2 2 0 Tho complex subunit 7 SlyX PF04102.12 EKX46736.1 - 0.16 12.6 7.2 5.3 7.7 0.8 3.5 2 1 1 3 3 2 0 SlyX DUF2730 PF10805.8 EKX46736.1 - 0.26 11.4 4.8 0.61 10.2 4.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Nmad5 PF18757.1 EKX46736.1 - 0.26 11.5 3.1 5.9 7.0 3.2 2.3 1 1 0 1 1 1 0 Nucleotide modification associated domain 5 HemX PF04375.14 EKX46736.1 - 0.28 10.4 4.7 0.46 9.7 4.7 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase TMPIT PF07851.13 EKX46736.1 - 0.3 10.3 3.3 0.53 9.5 3.3 1.4 1 0 0 1 1 1 0 TMPIT-like protein HOOK PF05622.12 EKX46736.1 - 0.35 9.0 10.7 0.98 7.5 1.9 1.8 1 1 1 2 2 2 0 HOOK protein Dabb PF07876.12 EKX46736.1 - 0.35 11.5 2.1 4.9 7.8 0.1 2.6 1 1 1 2 2 2 0 Stress responsive A/B Barrel Domain DUF16 PF01519.16 EKX46736.1 - 0.36 11.3 12.4 2.7 8.5 10.4 2.8 2 1 0 2 2 2 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 EKX46736.1 - 0.44 10.7 8.7 0.13 12.4 5.3 1.9 2 1 0 2 2 1 0 Fibrinogen alpha/beta chain family Snapin_Pallidin PF14712.6 EKX46736.1 - 0.46 10.9 9.6 1.8 9.0 2.8 2.5 1 1 1 2 2 2 0 Snapin/Pallidin Macoilin PF09726.9 EKX46736.1 - 0.47 9.0 8.2 0.93 8.0 8.4 1.5 1 1 0 1 1 1 0 Macoilin family HALZ PF02183.18 EKX46736.1 - 0.49 10.6 5.3 1.5 9.1 0.1 3.0 2 1 0 2 2 2 0 Homeobox associated leucine zipper CK2S PF15011.6 EKX46736.1 - 0.51 10.2 4.0 9.2 6.1 0.2 2.4 1 1 2 3 3 3 0 Casein Kinase 2 substrate Laminin_II PF06009.12 EKX46736.1 - 0.52 10.3 4.9 3.3 7.7 4.9 2.1 1 1 0 1 1 1 0 Laminin Domain II COX6A PF02046.15 EKX46736.1 - 0.6 10.6 2.7 0.84 10.1 0.0 2.3 2 1 0 2 2 1 0 Cytochrome c oxidase subunit VIa Fez1 PF06818.15 EKX46736.1 - 0.62 10.5 8.3 0.098 13.1 4.1 1.8 2 0 0 2 2 1 0 Fez1 Ax_dynein_light PF10211.9 EKX46736.1 - 0.64 9.9 9.3 1.8 8.5 8.8 1.9 1 1 0 1 1 1 0 Axonemal dynein light chain RmuC PF02646.16 EKX46736.1 - 0.72 8.9 7.1 4.1 6.5 1.8 2.2 1 1 1 2 2 2 0 RmuC family Helo_like_N PF17111.5 EKX46736.1 - 0.75 9.1 4.3 2.4 7.5 0.1 2.7 2 1 1 3 3 2 0 Fungal N-terminal domain of STAND proteins Prefoldin_2 PF01920.20 EKX46736.1 - 0.76 9.8 11.0 3.5 7.6 3.1 2.6 1 1 1 2 2 2 0 Prefoldin subunit DUF4407 PF14362.6 EKX46736.1 - 0.88 8.9 4.5 4.4 6.6 4.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF724 PF05266.14 EKX46736.1 - 0.99 9.2 9.7 0.2 11.5 5.7 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF724) ORF6C PF10552.9 EKX46736.1 - 1.2 9.2 4.8 5.8 7.0 0.6 3.1 2 1 1 3 3 3 0 ORF6C domain APG6_N PF17675.1 EKX46736.1 - 1.2 9.6 9.4 16 6.1 8.1 2.6 2 1 0 2 2 2 0 Apg6 coiled-coil region PspA_IM30 PF04012.12 EKX46736.1 - 1.3 8.5 9.4 0.34 10.5 0.9 2.4 1 1 1 2 2 2 0 PspA/IM30 family DMPK_coil PF08826.10 EKX46736.1 - 1.5 9.0 6.4 2.6 8.2 4.4 2.5 1 1 1 2 2 2 0 DMPK coiled coil domain like Filament PF00038.21 EKX46736.1 - 1.6 8.3 12.3 0.4 10.2 7.7 2.0 2 1 0 2 2 1 0 Intermediate filament protein Phage_GP20 PF06810.11 EKX46736.1 - 1.7 8.5 11.8 25 4.6 3.3 2.7 1 1 0 1 1 1 0 Phage minor structural protein GP20 Tektin PF03148.14 EKX46736.1 - 1.8 7.2 9.5 42 2.7 9.5 2.2 1 1 0 1 1 1 0 Tektin family CLZ PF16526.5 EKX46736.1 - 1.9 8.9 9.9 0.48 10.8 1.9 2.6 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ApoC-I PF04691.12 EKX46736.1 - 2 8.4 4.8 1.6 8.8 0.3 3.0 2 1 1 3 3 3 0 Apolipoprotein C-I (ApoC-1) DUF5320 PF17253.2 EKX46736.1 - 2.7 9.1 5.3 10 7.2 0.7 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5320) Tup_N PF08581.10 EKX46736.1 - 3.1 8.1 10.4 26 5.2 7.6 2.8 1 1 1 2 2 2 0 Tup N-terminal Occludin_ELL PF07303.13 EKX46736.1 - 3.4 8.4 10.3 10 6.9 0.2 3.3 3 1 1 4 4 2 0 Occludin homology domain HIP1_clath_bdg PF16515.5 EKX46736.1 - 3.5 8.3 15.5 0.53 10.9 7.3 2.7 2 1 1 3 3 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1640 PF07798.11 EKX46736.1 - 3.7 7.6 9.5 0.91 9.5 5.5 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF1640) WXG100 PF06013.12 EKX46736.1 - 4.7 7.5 7.8 1.4 9.2 2.9 2.4 2 1 1 3 3 2 0 Proteins of 100 residues with WXG ADIP PF11559.8 EKX46736.1 - 5.3 7.1 12.4 0.26 11.4 5.7 2.1 2 0 0 2 2 1 0 Afadin- and alpha -actinin-Binding CREPT PF16566.5 EKX46736.1 - 6 7.0 7.4 51 4.0 5.6 2.6 2 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour bZIP_1 PF00170.21 EKX46736.1 - 6.2 7.0 18.0 0.11 12.6 1.0 3.5 3 1 0 3 3 3 0 bZIP transcription factor Trimer_CC PF08954.11 EKX46736.1 - 9.8 5.8 7.1 5.3 6.7 0.7 2.8 2 1 0 2 2 2 0 Trimerisation motif EGF_CA PF07645.15 EKX46737.1 - 3e-10 40.2 27.0 8.3e-09 35.5 12.6 7.1 4 2 2 6 6 6 2 Calcium-binding EGF domain EGF_3 PF12947.7 EKX46737.1 - 5.7e-08 32.8 52.3 1.9e-07 31.2 11.1 6.0 5 1 0 5 5 5 3 EGF domain cEGF PF12662.7 EKX46737.1 - 0.00071 19.4 0.7 0.00071 19.4 0.7 6.8 6 1 0 6 6 6 3 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 EKX46737.1 - 0.0013 18.8 50.7 0.045 13.8 4.4 5.7 5 0 0 5 5 5 5 MSP1 EGF domain 1 FXa_inhibition PF14670.6 EKX46737.1 - 0.051 13.9 1.9 0.051 13.9 1.9 6.5 3 2 2 5 5 5 0 Coagulation Factor Xa inhibitory site CLPTM1 PF05602.12 EKX46738.1 - 5.8e-21 75.0 0.2 7.3e-21 74.7 0.2 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 EKX46738.1 - 0.025 14.4 0.0 0.066 13.0 0.0 1.7 1 0 0 1 1 1 0 PQ loop repeat DASH_Dam1 PF08653.10 EKX46739.1 - 3.2e-10 39.6 2.0 0.052 13.4 0.1 3.7 2 1 1 3 3 3 3 DASH complex subunit Dam1 Syntaxin-6_N PF09177.11 EKX46739.1 - 1.3e-06 28.8 6.5 0.2 12.2 1.4 3.7 1 1 2 3 3 3 3 Syntaxin 6, N-terminal TPR_MLP1_2 PF07926.12 EKX46739.1 - 5e-06 26.6 9.9 0.0018 18.3 4.8 2.7 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein Vps51 PF08700.11 EKX46739.1 - 8.2e-06 25.8 8.7 0.59 10.2 0.4 3.7 3 0 0 3 3 3 2 Vps51/Vps67 TACC_C PF05010.14 EKX46739.1 - 9.7e-06 25.5 18.0 1.7e-05 24.7 18.0 1.3 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal UPF0242 PF06785.11 EKX46739.1 - 1e-05 25.7 6.6 1.9e-05 24.9 6.6 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus PI3K_P85_iSH2 PF16454.5 EKX46739.1 - 1.3e-05 24.8 14.1 0.0068 16.0 6.3 3.2 1 1 2 3 3 3 3 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Gp58 PF07902.11 EKX46739.1 - 1.3e-05 23.7 0.3 2.1e-05 23.0 0.3 1.2 1 0 0 1 1 1 1 gp58-like protein Csm1_N PF18504.1 EKX46739.1 - 1.9e-05 24.9 12.1 0.55 10.6 0.5 4.3 1 1 3 4 4 4 2 Csm1 N-terminal domain FlaC_arch PF05377.11 EKX46739.1 - 3.8e-05 24.0 14.0 0.05 14.0 0.5 3.7 2 1 1 3 3 3 1 Flagella accessory protein C (FlaC) Lectin_N PF03954.14 EKX46739.1 - 5.5e-05 22.9 10.0 0.0013 18.5 2.5 2.4 1 1 1 2 2 2 1 Hepatic lectin, N-terminal domain DUF1664 PF07889.12 EKX46739.1 - 7.4e-05 22.8 14.0 0.0074 16.3 5.6 2.9 1 1 2 3 3 3 3 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 EKX46739.1 - 9.4e-05 22.6 18.1 0.036 14.3 10.1 3.3 1 1 1 2 2 2 2 Seryl-tRNA synthetase N-terminal domain AKNA PF12443.8 EKX46739.1 - 0.00011 22.8 12.6 1 10.1 1.1 3.6 1 1 2 3 3 3 1 AT-hook-containing transcription factor DUF3584 PF12128.8 EKX46739.1 - 0.00012 19.8 8.2 0.00018 19.2 8.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) NPV_P10 PF05531.12 EKX46739.1 - 0.00018 21.9 10.4 1.1 9.8 0.7 3.4 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein HMMR_N PF15905.5 EKX46739.1 - 0.00027 20.5 17.0 0.00043 19.9 17.0 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal BLOC1_2 PF10046.9 EKX46739.1 - 0.00033 20.9 13.2 0.024 14.9 2.0 3.1 1 1 1 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 AIP3 PF03915.13 EKX46739.1 - 0.00038 19.7 6.8 0.00061 19.0 6.8 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 Filament PF00038.21 EKX46739.1 - 0.0004 20.1 17.8 0.0037 16.9 8.4 2.7 2 1 1 3 3 2 2 Intermediate filament protein Fib_alpha PF08702.10 EKX46739.1 - 0.00055 20.1 10.2 0.012 15.8 9.5 2.6 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family DUF4618 PF15397.6 EKX46739.1 - 0.00071 19.1 15.3 0.046 13.1 11.1 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4618) Prefoldin PF02996.17 EKX46739.1 - 0.00079 19.3 11.1 0.74 9.7 1.5 3.7 2 1 2 4 4 3 1 Prefoldin subunit Spectrin PF00435.21 EKX46739.1 - 0.00091 19.7 13.9 0.0033 17.9 6.6 2.4 1 1 1 2 2 2 1 Spectrin repeat ZapB PF06005.12 EKX46739.1 - 0.00099 19.5 17.4 0.1 13.0 0.4 3.7 1 1 3 4 4 4 1 Cell division protein ZapB EzrA PF06160.12 EKX46739.1 - 0.001 17.4 10.4 0.0017 16.6 10.4 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Med9 PF07544.13 EKX46739.1 - 0.001 19.1 11.7 0.0077 16.3 4.3 2.8 1 1 1 2 2 2 2 RNA polymerase II transcription mediator complex subunit 9 DivIC PF04977.15 EKX46739.1 - 0.0011 18.7 10.4 0.25 11.1 0.2 3.5 2 1 1 3 3 3 1 Septum formation initiator CorA PF01544.18 EKX46739.1 - 0.0011 18.3 4.8 0.002 17.5 4.8 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Exonuc_VII_L PF02601.15 EKX46739.1 - 0.0015 18.2 2.2 0.0022 17.6 2.2 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit WXG100 PF06013.12 EKX46739.1 - 0.0024 18.1 7.2 3.6 7.9 0.3 3.4 1 1 2 3 3 3 0 Proteins of 100 residues with WXG Spc7 PF08317.11 EKX46739.1 - 0.0024 16.8 16.7 0.013 14.4 16.7 2.1 1 1 0 1 1 1 1 Spc7 kinetochore protein LXG PF04740.12 EKX46739.1 - 0.0024 17.6 9.2 2.6 7.7 0.3 3.4 1 1 2 3 3 3 0 LXG domain of WXG superfamily FmiP_Thoc5 PF09766.9 EKX46739.1 - 0.0026 17.1 11.0 0.15 11.3 3.9 2.9 1 1 2 3 3 3 2 Fms-interacting protein/Thoc5 THOC7 PF05615.13 EKX46739.1 - 0.0027 18.0 11.1 1.8 8.9 1.5 3.4 1 1 2 3 3 3 0 Tho complex subunit 7 DUF4407 PF14362.6 EKX46739.1 - 0.0035 16.7 5.0 0.0081 15.6 5.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) SlyX PF04102.12 EKX46739.1 - 0.0042 17.7 10.4 4.8 7.9 0.6 4.1 1 1 2 3 3 3 0 SlyX GAS PF13851.6 EKX46739.1 - 0.0043 16.4 20.5 0.01 15.2 8.3 3.0 2 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding Muted PF14942.6 EKX46739.1 - 0.0045 17.3 14.8 0.08 13.3 13.1 2.4 1 1 1 2 2 2 2 Organelle biogenesis, Muted-like protein AP_endonuc_2_N PF07582.12 EKX46739.1 - 0.0046 16.7 0.9 16 5.3 0.0 3.4 3 0 0 3 3 3 0 AP endonuclease family 2 C terminus Apolipoprotein PF01442.18 EKX46739.1 - 0.0055 16.6 8.9 0.012 15.5 8.9 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain CCDC154 PF15450.6 EKX46739.1 - 0.0062 15.1 9.8 0.0089 14.6 9.8 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 154 Rbsn PF11464.8 EKX46739.1 - 0.0064 16.2 3.8 23 4.8 0.1 4.1 3 0 0 3 3 3 0 Rabenosyn Rab binding domain SKA2 PF16740.5 EKX46739.1 - 0.0066 16.2 10.6 0.0087 15.8 5.6 2.4 1 1 1 2 2 2 2 Spindle and kinetochore-associated protein 2 DUF677 PF05055.12 EKX46739.1 - 0.0069 15.3 10.6 0.22 10.3 10.6 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF677) AAA_13 PF13166.6 EKX46739.1 - 0.0071 15.1 5.9 0.011 14.5 5.9 1.2 1 0 0 1 1 1 1 AAA domain Rab5-bind PF09311.11 EKX46739.1 - 0.0076 15.7 11.4 0.014 14.8 11.4 1.4 1 0 0 1 1 1 1 Rabaptin-like protein PspA_IM30 PF04012.12 EKX46739.1 - 0.0085 15.7 14.7 0.46 10.0 0.9 3.4 1 1 2 3 3 3 1 PspA/IM30 family PfUIS3 PF11567.8 EKX46739.1 - 0.0088 16.4 9.2 7.7 6.9 0.9 4.4 2 2 2 4 4 4 0 Plasmodium falciparum UIS3 membrane protein Lebercilin PF15619.6 EKX46739.1 - 0.0089 15.7 6.2 0.0089 15.7 6.2 2.8 2 1 1 3 3 2 2 Ciliary protein causing Leber congenital amaurosis disease KxDL PF10241.9 EKX46739.1 - 0.01 16.1 10.8 0.8 10.0 0.5 3.5 1 1 2 3 3 3 1 Uncharacterized conserved protein Baculo_PEP_C PF04513.12 EKX46739.1 - 0.01 15.9 0.5 0.033 14.2 0.5 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus MAD PF05557.13 EKX46739.1 - 0.01 14.2 12.8 0.019 13.3 12.8 1.4 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF812 PF05667.11 EKX46739.1 - 0.01 14.7 16.3 0.081 11.8 16.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF812) YabA PF06156.13 EKX46739.1 - 0.01 16.4 13.0 0.022 15.4 3.7 2.6 1 1 1 2 2 2 0 Initiation control protein YabA CCDC144C PF14915.6 EKX46739.1 - 0.011 14.9 17.7 0.045 12.9 7.8 2.2 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region bZIP_1 PF00170.21 EKX46739.1 - 0.011 15.8 25.6 0.13 12.4 1.0 4.5 3 1 1 4 4 4 0 bZIP transcription factor Leu_zip PF15294.6 EKX46739.1 - 0.011 15.2 14.3 0.022 14.3 14.3 1.4 1 0 0 1 1 1 0 Leucine zipper ADIP PF11559.8 EKX46739.1 - 0.012 15.7 9.8 0.012 15.7 9.8 2.4 2 1 1 3 3 2 0 Afadin- and alpha -actinin-Binding LPP PF04728.13 EKX46739.1 - 0.013 15.8 6.0 15 6.1 0.1 3.7 3 0 0 3 3 3 0 Lipoprotein leucine-zipper DUF948 PF06103.11 EKX46739.1 - 0.014 15.6 10.3 1.4 9.3 3.4 3.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3972 PF13118.6 EKX46739.1 - 0.015 15.8 11.7 0.18 12.3 8.6 3.0 2 1 1 3 3 2 0 Protein of unknown function (DUF3972) TelA PF05816.11 EKX46739.1 - 0.016 14.3 12.5 0.023 13.8 12.5 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) HALZ PF02183.18 EKX46739.1 - 0.02 15.1 8.6 1.7 8.9 0.1 4.2 3 1 1 4 4 4 0 Homeobox associated leucine zipper Helo_like_N PF17111.5 EKX46739.1 - 0.022 14.2 9.4 2.8 7.3 0.1 3.6 2 1 2 4 4 3 0 Fungal N-terminal domain of STAND proteins YscO PF07321.12 EKX46739.1 - 0.024 14.6 10.2 0.11 12.4 8.2 2.6 1 1 1 2 2 2 0 Type III secretion protein YscO DUF4988 PF16378.5 EKX46739.1 - 0.024 14.3 6.0 1.9 8.1 0.2 3.2 1 1 2 3 3 3 0 Domain of unknown function HIP1_clath_bdg PF16515.5 EKX46739.1 - 0.024 15.2 19.5 1.7 9.3 7.9 3.0 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Snapin_Pallidin PF14712.6 EKX46739.1 - 0.027 14.9 12.2 0.14 12.6 3.1 2.7 1 1 1 2 2 2 0 Snapin/Pallidin Laminin_II PF06009.12 EKX46739.1 - 0.027 14.5 9.8 2.4 8.2 4.5 2.8 1 1 1 2 2 2 0 Laminin Domain II AAA_32 PF13654.6 EKX46739.1 - 0.028 13.2 8.7 0.4 9.4 1.2 2.1 1 1 1 2 2 2 0 AAA domain SHE3 PF17078.5 EKX46739.1 - 0.029 14.1 9.4 0.074 12.8 9.4 1.7 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DASH_Dad2 PF08654.10 EKX46739.1 - 0.029 14.8 8.6 2.5 8.6 0.1 3.5 3 0 0 3 3 3 0 DASH complex subunit Dad2 DUF5082 PF16888.5 EKX46739.1 - 0.03 14.6 8.6 0.094 13.0 8.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF3450 PF11932.8 EKX46739.1 - 0.035 13.4 12.9 0.39 10.0 5.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Prefoldin_2 PF01920.20 EKX46739.1 - 0.035 14.1 20.2 0.64 10.0 3.7 3.5 1 1 2 3 3 3 0 Prefoldin subunit Allexi_40kDa PF05549.11 EKX46739.1 - 0.036 13.6 5.9 0.18 11.3 0.9 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein ApoLp-III PF07464.11 EKX46739.1 - 0.041 14.0 9.1 0.15 12.2 8.8 1.9 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) ORF6C PF10552.9 EKX46739.1 - 0.043 13.9 12.6 3.5 7.7 0.6 4.0 2 1 2 4 4 3 0 ORF6C domain YkyA PF10368.9 EKX46739.1 - 0.048 13.3 16.7 0.077 12.7 7.8 2.3 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein Nmad5 PF18757.1 EKX46739.1 - 0.049 13.8 7.9 0.31 11.2 7.9 2.8 1 1 0 1 1 1 0 Nucleotide modification associated domain 5 Dabb PF07876.12 EKX46739.1 - 0.05 14.2 6.3 5.7 7.6 0.1 3.5 1 1 2 3 3 3 0 Stress responsive A/B Barrel Domain APG17 PF04108.12 EKX46739.1 - 0.052 12.6 8.4 0.19 10.8 8.4 1.7 1 1 0 1 1 1 0 Autophagy protein Apg17 DUF2959 PF11172.8 EKX46739.1 - 0.054 13.6 5.0 0.14 12.3 5.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2959) Fez1 PF06818.15 EKX46739.1 - 0.058 13.8 15.6 0.18 12.2 15.6 1.9 1 1 0 1 1 1 0 Fez1 CK2S PF15011.6 EKX46739.1 - 0.066 13.1 8.3 7.5 6.4 1.0 3.2 1 1 2 3 3 3 0 Casein Kinase 2 substrate CENP-K PF11802.8 EKX46739.1 - 0.073 12.6 11.1 0.14 11.7 11.1 1.5 1 0 0 1 1 1 0 Centromere-associated protein K DUF2730 PF10805.8 EKX46739.1 - 0.074 13.2 10.6 1.2 9.3 4.4 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) MbeD_MobD PF04899.12 EKX46739.1 - 0.076 13.1 2.5 15 5.8 0.1 3.3 1 1 2 3 3 3 0 MbeD/MobD like HalX PF08663.10 EKX46739.1 - 0.076 13.3 2.6 19 5.6 0.1 3.7 1 1 2 3 3 2 0 HalX domain CALCOCO1 PF07888.11 EKX46739.1 - 0.086 11.7 14.1 1.6 7.5 14.0 2.0 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Bacillus_HBL PF05791.11 EKX46739.1 - 0.11 12.4 7.9 0.54 10.1 4.0 2.5 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) SesA PF17107.5 EKX46739.1 - 0.12 12.6 1.4 0.47 10.7 1.4 1.9 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Ax_dynein_light PF10211.9 EKX46739.1 - 0.12 12.3 18.1 0.47 10.4 8.1 2.5 1 1 2 3 3 3 0 Axonemal dynein light chain Zw10 PF06248.13 EKX46739.1 - 0.13 10.8 5.0 0.19 10.2 5.0 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Occludin_ELL PF07303.13 EKX46739.1 - 0.13 13.0 12.9 0.34 11.7 3.0 3.1 3 1 1 4 4 2 0 Occludin homology domain CEP63 PF17045.5 EKX46739.1 - 0.14 12.1 14.4 0.27 11.1 6.8 2.2 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa Fzo_mitofusin PF04799.13 EKX46739.1 - 0.14 11.7 11.7 3.8 7.1 2.1 3.5 1 1 3 4 4 4 0 fzo-like conserved region Cytochrom_B562 PF07361.11 EKX46739.1 - 0.15 12.7 14.0 2.5 8.8 5.0 2.7 1 1 1 2 2 2 0 Cytochrome b562 Phage_GPO PF05929.11 EKX46739.1 - 0.15 11.7 11.1 1 8.9 3.4 2.1 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF16 PF01519.16 EKX46739.1 - 0.16 12.5 18.8 1.6 9.2 3.2 3.2 2 1 1 3 3 2 0 Protein of unknown function DUF16 Golgin_A5 PF09787.9 EKX46739.1 - 0.16 11.4 17.4 0.56 9.6 17.4 1.7 1 1 0 1 1 1 0 Golgin subfamily A member 5 Mod_r PF07200.13 EKX46739.1 - 0.17 12.0 12.2 1.6 8.9 4.3 2.7 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein RmuC PF02646.16 EKX46739.1 - 0.18 10.9 12.5 0.54 9.3 3.5 2.6 1 1 1 2 2 2 0 RmuC family Syntaxin PF00804.25 EKX46739.1 - 0.19 11.4 12.8 0.76 9.4 3.8 2.7 1 1 2 3 3 3 0 Syntaxin DUF4455 PF14643.6 EKX46739.1 - 0.22 10.1 12.2 0.31 9.6 11.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4455) DUF4200 PF13863.6 EKX46739.1 - 0.29 11.6 21.8 1 9.8 3.2 3.6 2 1 2 4 4 3 0 Domain of unknown function (DUF4200) Phage_GP20 PF06810.11 EKX46739.1 - 0.3 10.9 20.4 4.4 7.1 9.9 3.6 1 1 2 3 3 3 0 Phage minor structural protein GP20 Atg14 PF10186.9 EKX46739.1 - 0.33 10.0 6.6 0.71 8.9 6.3 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 IFT57 PF10498.9 EKX46739.1 - 0.33 9.9 13.8 0.2 10.6 4.3 1.9 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Trimer_CC PF08954.11 EKX46739.1 - 0.34 10.5 10.0 5.4 6.6 0.1 3.8 3 1 0 3 3 3 0 Trimerisation motif Prominin PF05478.11 EKX46739.1 - 0.36 8.8 8.9 1.6 6.6 8.9 1.8 1 1 0 1 1 1 0 Prominin DASH_Duo1 PF08651.10 EKX46739.1 - 0.41 10.5 5.6 32 4.4 0.2 3.5 3 0 0 3 3 3 0 DASH complex subunit Duo1 APG6_N PF17675.1 EKX46739.1 - 0.42 11.1 17.1 1.1 9.7 5.3 3.2 2 1 1 3 3 3 0 Apg6 coiled-coil region GrpE PF01025.19 EKX46739.1 - 0.42 10.2 15.3 5.7 6.6 5.4 2.9 1 1 1 2 2 2 0 GrpE DUF4164 PF13747.6 EKX46739.1 - 0.43 10.9 8.8 1.1 9.5 1.6 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) CLZ PF16526.5 EKX46739.1 - 0.44 10.9 19.6 0.67 10.4 2.2 3.4 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Sec34 PF04136.15 EKX46739.1 - 0.45 10.4 10.6 2.7 7.9 2.3 3.5 2 1 1 3 3 2 0 Sec34-like family LOH1CR12 PF10158.9 EKX46739.1 - 0.5 10.4 3.8 1.3 9.0 0.3 2.3 1 1 2 3 3 3 0 Tumour suppressor protein Jnk-SapK_ap_N PF09744.9 EKX46739.1 - 0.52 10.5 17.2 0.25 11.5 6.3 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 T3SSipB PF16535.5 EKX46739.1 - 0.52 10.8 6.7 1 9.8 1.5 2.6 1 1 2 3 3 3 0 Type III cell invasion protein SipB DUF724 PF05266.14 EKX46739.1 - 0.52 10.1 16.9 3.2 7.5 6.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) MbeB_N PF04837.12 EKX46739.1 - 0.6 10.5 7.2 9 6.7 0.2 3.3 3 0 0 3 3 2 0 MbeB-like, N-term conserved region DUF4662 PF15578.6 EKX46739.1 - 0.63 9.8 4.1 8.1 6.2 0.3 2.6 2 1 1 3 3 2 0 Domain of unknown function (DUF4662) Sec20 PF03908.13 EKX46739.1 - 0.83 9.6 4.3 11 6.1 0.4 2.8 1 1 1 2 2 2 0 Sec20 TMPIT PF07851.13 EKX46739.1 - 0.94 8.7 11.5 2.8 7.1 5.0 2.0 1 1 1 2 2 2 0 TMPIT-like protein Mt_ATP-synt_D PF05873.12 EKX46739.1 - 0.97 9.3 8.8 83 3.0 0.8 3.5 2 1 1 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) DUF4140 PF13600.6 EKX46739.1 - 1.1 9.8 6.6 58 4.2 0.2 3.8 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) Spc29 PF17082.5 EKX46739.1 - 1.1 9.0 7.7 3.7 7.3 0.7 2.5 1 1 1 2 2 2 0 Spindle Pole Component 29 DUF4446 PF14584.6 EKX46739.1 - 1.3 9.0 12.1 9.7 6.2 1.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) YtxH PF12732.7 EKX46739.1 - 1.5 9.4 11.3 2.8e+03 -1.1 11.3 3.4 1 1 0 1 1 0 0 YtxH-like protein LRRFIP PF09738.9 EKX46739.1 - 1.5 8.2 15.6 2.5 7.5 3.0 2.6 1 1 0 2 2 2 0 LRRFIP family DUF4175 PF13779.6 EKX46739.1 - 1.7 6.5 14.5 2.4 6.0 14.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Rootletin PF15035.6 EKX46739.1 - 1.7 8.6 12.3 2 8.4 5.1 2.4 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion KfrA_N PF11740.8 EKX46739.1 - 1.7 9.3 4.8 12 6.6 0.9 3.1 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Nup88 PF10168.9 EKX46739.1 - 1.8 6.3 13.0 12 3.6 13.5 1.9 2 1 0 2 2 1 0 Nuclear pore component Baculo_F PF12259.8 EKX46739.1 - 1.9 6.9 6.0 2.2 6.7 1.2 1.8 1 1 1 2 2 2 0 Baculovirus F protein GARP PF16731.5 EKX46739.1 - 1.9 8.2 7.4 14 5.3 0.7 3.3 1 1 2 3 3 3 0 Glutamic acid/alanine-rich protein of Trypanosoma Tmemb_cc2 PF10267.9 EKX46739.1 - 1.9 7.5 18.1 26 3.8 18.3 2.2 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF5320 PF17253.2 EKX46739.1 - 1.9 9.6 10.3 15 6.7 0.3 3.5 1 1 2 3 3 3 0 Family of unknown function (DUF5320) HrpB7 PF09486.10 EKX46739.1 - 2.1 8.7 5.7 15 6.0 1.1 2.4 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF641 PF04859.12 EKX46739.1 - 2.1 8.7 11.9 13 6.1 5.0 2.7 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Tektin PF03148.14 EKX46739.1 - 2.2 6.9 16.2 2.1 7.0 8.0 2.5 1 1 1 2 2 2 0 Tektin family GBP_C PF02841.14 EKX46739.1 - 2.2 7.6 19.1 0.06 12.7 8.4 2.1 1 1 1 2 2 2 0 Guanylate-binding protein, C-terminal domain Tropomyosin_1 PF12718.7 EKX46739.1 - 2.3 8.4 25.9 16 5.6 21.0 2.9 2 1 0 2 2 1 0 Tropomyosin like DUF745 PF05335.13 EKX46739.1 - 2.5 7.8 6.8 7.8 6.2 6.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF745) Fmp27_WPPW PF10359.9 EKX46739.1 - 2.8 6.7 12.6 2.2 7.0 4.6 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain FAM76 PF16046.5 EKX46739.1 - 2.9 7.1 13.9 5.1 6.3 13.9 1.3 1 0 0 1 1 1 0 FAM76 protein SYCE1 PF15233.6 EKX46739.1 - 3 7.9 16.3 1.9 8.5 1.5 3.0 1 1 2 3 3 3 0 Synaptonemal complex central element protein 1 Macoilin PF09726.9 EKX46739.1 - 3 6.3 14.4 36 2.7 14.5 2.1 1 1 0 1 1 1 0 Macoilin family V_ATPase_I PF01496.19 EKX46739.1 - 3.1 5.6 11.0 6.7 4.5 11.0 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.11 EKX46739.1 - 3.5 7.9 16.9 26 5.1 0.7 3.7 2 1 1 3 3 2 0 Spc24 subunit of Ndc80 OmpH PF03938.14 EKX46739.1 - 3.8 7.8 17.6 4.8 7.5 12.7 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) TSNAXIP1_N PF15739.5 EKX46739.1 - 4 7.8 10.7 5.4 7.4 2.4 2.8 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus EMP24_GP25L PF01105.24 EKX46739.1 - 4.1 7.3 13.2 34 4.3 3.5 3.3 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF2968 PF11180.8 EKX46739.1 - 4.1 7.0 9.6 15 5.2 2.9 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF2968) Cnn_1N PF07989.11 EKX46739.1 - 4.3 7.6 19.9 1.6 8.9 5.6 3.4 2 1 1 3 3 2 0 Centrosomin N-terminal motif 1 KI67R PF08065.12 EKX46739.1 - 4.9 7.7 9.6 6.4 7.4 4.1 2.4 1 1 1 2 2 2 0 KI67R (NUC007) repeat UPF0449 PF15136.6 EKX46739.1 - 5.4 7.5 11.0 28 5.3 0.7 3.5 1 1 2 3 3 3 0 Uncharacterised protein family UPF0449 Hemagglutinin PF00509.18 EKX46739.1 - 5.6 5.2 6.9 4.7 5.5 2.1 2.0 1 1 1 2 2 2 0 Haemagglutinin Laminin_I PF06008.14 EKX46739.1 - 6.1 6.5 15.3 15 5.2 1.0 2.5 1 1 1 2 2 2 0 Laminin Domain I HemX PF04375.14 EKX46739.1 - 6.1 6.0 10.9 2.1 7.5 3.8 2.1 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase XhlA PF10779.9 EKX46739.1 - 6.2 7.1 19.8 4.6 7.5 3.3 4.2 1 1 3 4 4 4 0 Haemolysin XhlA DHR10 PF18595.1 EKX46739.1 - 7.6 6.6 17.1 15 5.7 1.0 3.2 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain PRKG1_interact PF15898.5 EKX46739.1 - 8.6 7.3 16.5 25 5.8 0.5 3.1 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain End3 PF12761.7 EKX46739.1 - 9.3 6.4 15.0 20 5.3 2.3 3.0 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 CREPT PF16566.5 EKX46739.1 - 9.4 6.4 12.8 13 5.9 1.8 3.2 2 1 1 3 3 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF5556 PF17711.1 EKX46740.1 - 0.082 12.8 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5556) Atg14 PF10186.9 EKX46741.1 - 0.0053 15.9 5.1 0.0062 15.7 5.1 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 EKX46741.1 - 0.0066 15.7 1.3 0.0076 15.5 1.3 1.0 1 0 0 1 1 1 1 TMPIT-like protein DUF5082 PF16888.5 EKX46741.1 - 0.0074 16.6 0.6 0.0074 16.6 0.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) T2SSM PF04612.12 EKX46741.1 - 0.011 15.9 1.5 0.014 15.4 1.5 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Gp58 PF07902.11 EKX46741.1 - 0.012 13.9 0.3 0.012 13.9 0.3 1.1 1 0 0 1 1 1 0 gp58-like protein Cluap1 PF10234.9 EKX46741.1 - 0.013 14.9 1.6 0.013 14.9 1.6 1.4 2 0 0 2 2 2 0 Clusterin-associated protein-1 DUF4407 PF14362.6 EKX46741.1 - 0.029 13.7 3.3 0.031 13.6 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GIT_CC PF16559.5 EKX46741.1 - 0.044 13.7 2.3 1.3 8.9 0.6 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Spc24 PF08286.11 EKX46741.1 - 0.054 13.7 1.0 0.068 13.4 1.0 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 OmpH PF03938.14 EKX46741.1 - 0.12 12.7 5.4 0.15 12.4 5.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) kleA_kleC PF17383.2 EKX46741.1 - 0.12 12.7 1.4 1.5 9.2 0.6 2.2 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A CLZ PF16526.5 EKX46741.1 - 0.14 12.5 4.7 0.11 12.9 1.7 2.0 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FliJ PF02050.16 EKX46741.1 - 0.16 12.2 5.9 0.13 12.5 4.3 1.6 1 1 0 1 1 1 0 Flagellar FliJ protein DUF4140 PF13600.6 EKX46741.1 - 0.17 12.3 3.9 0.11 13.0 1.4 1.9 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF641 PF04859.12 EKX46741.1 - 0.18 12.1 5.6 1.4 9.2 2.0 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) ubiquitin PF00240.23 EKX46741.1 - 0.35 10.7 2.7 19 5.1 0.0 2.4 2 1 0 2 2 2 0 Ubiquitin family Csm1_N PF18504.1 EKX46741.1 - 0.35 11.2 6.4 0.14 12.5 2.9 2.0 2 0 0 2 2 2 0 Csm1 N-terminal domain Spc7 PF08317.11 EKX46741.1 - 0.46 9.3 6.9 0.23 10.3 4.9 1.4 1 1 1 2 2 2 0 Spc7 kinetochore protein DivIC PF04977.15 EKX46741.1 - 0.53 10.1 6.4 0.12 12.2 2.9 1.6 2 0 0 2 2 2 0 Septum formation initiator DASH_Dam1 PF08653.10 EKX46742.1 - 6.3e-08 32.3 1.4 0.014 15.2 0.1 3.2 1 1 1 2 2 2 2 DASH complex subunit Dam1 PI3K_P85_iSH2 PF16454.5 EKX46742.1 - 1.9e-07 30.8 10.7 6.5e-05 22.6 2.2 2.2 1 1 1 2 2 2 2 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF812 PF05667.11 EKX46742.1 - 1.3e-06 27.6 4.7 1.7e-06 27.3 4.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Syntaxin-6_N PF09177.11 EKX46742.1 - 4.7e-06 27.1 3.9 0.0036 17.8 2.0 2.4 1 1 1 2 2 2 2 Syntaxin 6, N-terminal Spc7 PF08317.11 EKX46742.1 - 5.2e-06 25.6 6.3 7.2e-06 25.1 6.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein NPV_P10 PF05531.12 EKX46742.1 - 1.1e-05 25.8 4.4 0.013 16.0 0.6 2.2 2 0 0 2 2 2 2 Nucleopolyhedrovirus P10 protein Gp58 PF07902.11 EKX46742.1 - 1.7e-05 23.4 0.6 2.7e-05 22.7 0.6 1.3 1 1 0 1 1 1 1 gp58-like protein TPR_MLP1_2 PF07926.12 EKX46742.1 - 3.5e-05 23.9 7.6 0.00047 20.2 6.5 2.3 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.11 EKX46742.1 - 4.7e-05 23.7 8.6 0.0056 17.1 1.0 3.0 1 1 3 4 4 3 1 Flagella accessory protein C (FlaC) Lectin_N PF03954.14 EKX46742.1 - 5.7e-05 22.9 6.2 6.3e-05 22.7 3.6 1.9 1 1 1 2 2 2 1 Hepatic lectin, N-terminal domain Csm1_N PF18504.1 EKX46742.1 - 8.2e-05 22.9 10.9 0.059 13.7 1.0 3.5 1 1 2 3 3 3 2 Csm1 N-terminal domain Fib_alpha PF08702.10 EKX46742.1 - 8.3e-05 22.8 5.7 0.00013 22.2 5.7 1.3 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family DUF4988 PF16378.5 EKX46742.1 - 8.6e-05 22.3 1.4 0.009 15.7 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function bZIP_1 PF00170.21 EKX46742.1 - 9.8e-05 22.4 12.0 0.0034 17.4 2.6 2.7 2 1 1 3 3 2 2 bZIP transcription factor FapA PF03961.13 EKX46742.1 - 0.0001 21.1 1.9 0.0001 21.1 1.9 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A Filament PF00038.21 EKX46742.1 - 0.00011 21.9 8.8 0.00011 21.9 8.8 1.4 1 1 0 1 1 1 1 Intermediate filament protein DUF1664 PF07889.12 EKX46742.1 - 0.00012 22.1 9.3 0.00024 21.1 6.5 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) GAS PF13851.6 EKX46742.1 - 0.00013 21.4 10.3 0.00018 20.9 10.3 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding CCDC144C PF14915.6 EKX46742.1 - 0.00017 20.9 9.3 0.00024 20.3 9.3 1.2 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region DUF677 PF05055.12 EKX46742.1 - 0.0002 20.4 1.8 0.00026 20.0 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF677) Vps51 PF08700.11 EKX46742.1 - 0.00036 20.6 7.8 0.16 12.1 0.4 3.0 2 1 1 3 3 3 2 Vps51/Vps67 UPF0242 PF06785.11 EKX46742.1 - 0.00042 20.5 5.0 0.00051 20.2 5.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Seryl_tRNA_N PF02403.22 EKX46742.1 - 0.00047 20.4 12.9 0.17 12.2 12.9 2.5 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain ZapB PF06005.12 EKX46742.1 - 0.00051 20.4 13.5 0.0099 16.3 2.0 2.7 1 1 1 2 2 2 1 Cell division protein ZapB BLOC1_2 PF10046.9 EKX46742.1 - 0.00057 20.1 10.1 0.012 15.9 1.9 2.2 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Lebercilin PF15619.6 EKX46742.1 - 0.00064 19.4 10.6 0.00093 18.9 10.6 1.3 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease Med9 PF07544.13 EKX46742.1 - 0.00074 19.5 7.9 0.0012 18.9 6.0 2.1 1 1 1 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Macoilin PF09726.9 EKX46742.1 - 0.00078 18.1 3.3 0.0011 17.7 3.3 1.3 1 0 0 1 1 1 1 Macoilin family DUF4618 PF15397.6 EKX46742.1 - 0.00079 18.9 11.1 0.014 14.9 8.4 1.9 1 1 1 2 2 2 2 Domain of unknown function (DUF4618) FmiP_Thoc5 PF09766.9 EKX46742.1 - 0.00088 18.7 9.0 0.045 13.0 2.6 2.0 1 1 1 2 2 2 2 Fms-interacting protein/Thoc5 Rab5-bind PF09311.11 EKX46742.1 - 0.00098 18.6 7.7 0.0013 18.2 7.7 1.1 1 0 0 1 1 1 1 Rabaptin-like protein HMMR_N PF15905.5 EKX46742.1 - 0.0011 18.6 10.3 0.0016 18.0 10.3 1.3 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal DUF3972 PF13118.6 EKX46742.1 - 0.0011 19.4 8.1 0.0024 18.3 8.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3972) Fez1 PF06818.15 EKX46742.1 - 0.0012 19.4 8.3 0.0017 18.8 8.3 1.2 1 0 0 1 1 1 1 Fez1 AIP3 PF03915.13 EKX46742.1 - 0.0013 18.0 2.8 0.0015 17.7 2.8 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 DUF3584 PF12128.8 EKX46742.1 - 0.0014 16.3 6.6 0.0018 15.9 6.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) WXG100 PF06013.12 EKX46742.1 - 0.0014 18.8 3.9 0.43 10.8 0.5 2.5 1 1 1 2 2 2 1 Proteins of 100 residues with WXG Helo_like_N PF17111.5 EKX46742.1 - 0.0015 17.9 3.1 0.073 12.4 0.3 2.2 1 1 1 2 2 2 1 Fungal N-terminal domain of STAND proteins DivIC PF04977.15 EKX46742.1 - 0.0018 18.0 8.1 0.055 13.3 1.4 2.4 2 1 0 2 2 2 1 Septum formation initiator HOOK PF05622.12 EKX46742.1 - 0.0019 16.5 14.2 0.0036 15.5 14.2 1.3 1 1 0 1 1 1 1 HOOK protein LXG PF04740.12 EKX46742.1 - 0.002 17.9 4.3 0.33 10.6 0.5 2.2 1 1 1 2 2 2 1 LXG domain of WXG superfamily Exonuc_VII_L PF02601.15 EKX46742.1 - 0.0021 17.7 1.0 0.0024 17.5 1.0 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit PspA_IM30 PF04012.12 EKX46742.1 - 0.0023 17.5 9.4 0.064 12.8 2.0 2.2 1 1 1 2 2 2 1 PspA/IM30 family Golgin_A5 PF09787.9 EKX46742.1 - 0.0024 17.4 9.4 0.0032 17.0 9.4 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 AKNA PF12443.8 EKX46742.1 - 0.0027 18.3 10.4 0.23 12.1 1.0 3.0 1 1 1 2 2 2 1 AT-hook-containing transcription factor Allexi_40kDa PF05549.11 EKX46742.1 - 0.0027 17.2 2.3 0.004 16.7 2.3 1.3 1 0 0 1 1 1 1 Allexivirus 40kDa protein Baculo_PEP_C PF04513.12 EKX46742.1 - 0.0031 17.6 0.3 0.0041 17.2 0.3 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_32 PF13654.6 EKX46742.1 - 0.0036 16.2 4.4 0.0049 15.7 4.4 1.2 1 0 0 1 1 1 1 AAA domain HALZ PF02183.18 EKX46742.1 - 0.0038 17.4 8.1 0.77 10.0 0.0 3.8 2 2 2 4 4 4 1 Homeobox associated leucine zipper IFT57 PF10498.9 EKX46742.1 - 0.004 16.2 8.2 0.0051 15.8 8.2 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 SlyX PF04102.12 EKX46742.1 - 0.0041 17.7 9.5 1.2 9.9 4.0 3.3 1 1 1 2 2 2 0 SlyX ApoLp-III PF07464.11 EKX46742.1 - 0.0044 17.1 5.8 0.0073 16.4 5.8 1.4 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) Tropomyosin_1 PF12718.7 EKX46742.1 - 0.0045 17.2 15.2 0.0074 16.5 15.2 1.3 1 0 0 1 1 1 1 Tropomyosin like TACC_C PF05010.14 EKX46742.1 - 0.0047 16.8 12.6 0.011 15.6 12.6 1.5 1 1 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal THOC7 PF05615.13 EKX46742.1 - 0.0056 17.0 8.5 0.45 10.8 1.5 2.3 1 1 1 2 2 2 1 Tho complex subunit 7 Prominin PF05478.11 EKX46742.1 - 0.0063 14.5 6.7 0.016 13.2 6.8 1.5 1 1 0 1 1 1 1 Prominin Prefoldin PF02996.17 EKX46742.1 - 0.0065 16.4 8.4 0.56 10.1 0.9 2.6 1 1 0 2 2 2 1 Prefoldin subunit YscO PF07321.12 EKX46742.1 - 0.0077 16.2 7.3 0.038 14.0 7.3 2.1 1 1 0 1 1 1 1 Type III secretion protein YscO Laminin_II PF06009.12 EKX46742.1 - 0.008 16.2 6.5 0.027 14.5 6.6 1.8 1 1 0 1 1 1 1 Laminin Domain II YkyA PF10368.9 EKX46742.1 - 0.0082 15.8 12.6 0.027 14.2 12.6 1.7 1 1 0 1 1 1 1 Putative cell-wall binding lipoprotein TMPIT PF07851.13 EKX46742.1 - 0.0083 15.4 3.8 0.013 14.8 3.8 1.3 1 0 0 1 1 1 1 TMPIT-like protein Bacillus_HBL PF05791.11 EKX46742.1 - 0.0088 15.9 6.1 0.014 15.3 6.1 1.4 1 1 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) Spectrin PF00435.21 EKX46742.1 - 0.0089 16.5 11.1 0.15 12.6 10.5 2.3 1 1 0 1 1 1 1 Spectrin repeat LPP PF04728.13 EKX46742.1 - 0.0093 16.3 4.3 4.7 7.7 0.1 3.2 2 1 0 2 2 2 0 Lipoprotein leucine-zipper AAA_13 PF13166.6 EKX46742.1 - 0.0098 14.6 3.4 0.013 14.2 3.4 1.1 1 0 0 1 1 1 1 AAA domain Prefoldin_2 PF01920.20 EKX46742.1 - 0.0099 15.8 16.3 0.17 11.8 3.9 3.0 1 1 2 3 3 3 1 Prefoldin subunit CENP-K PF11802.8 EKX46742.1 - 0.01 15.4 4.0 0.014 15.0 4.0 1.2 1 0 0 1 1 1 0 Centromere-associated protein K Occludin_ELL PF07303.13 EKX46742.1 - 0.01 16.5 6.0 0.042 14.6 4.1 2.3 1 1 2 3 3 3 0 Occludin homology domain DUF16 PF01519.16 EKX46742.1 - 0.011 16.3 12.2 0.073 13.6 3.0 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF948 PF06103.11 EKX46742.1 - 0.013 15.8 7.3 0.34 11.2 2.0 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Apolipoprotein PF01442.18 EKX46742.1 - 0.013 15.4 6.5 0.022 14.6 6.5 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF4200 PF13863.6 EKX46742.1 - 0.013 15.9 13.1 0.33 11.3 3.8 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) HemX PF04375.14 EKX46742.1 - 0.014 14.7 5.1 0.022 14.1 5.1 1.3 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase SKA2 PF16740.5 EKX46742.1 - 0.014 15.2 8.7 0.18 11.6 6.2 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Mod_r PF07200.13 EKX46742.1 - 0.015 15.4 9.4 0.42 10.7 1.1 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein EzrA PF06160.12 EKX46742.1 - 0.016 13.4 9.9 0.04 12.1 10.0 1.3 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Muted PF14942.6 EKX46742.1 - 0.016 15.5 11.0 0.068 13.5 11.0 1.9 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein CK2S PF15011.6 EKX46742.1 - 0.017 15.0 5.7 0.67 9.8 0.5 2.4 1 1 1 2 2 2 0 Casein Kinase 2 substrate DUF724 PF05266.14 EKX46742.1 - 0.017 15.0 11.2 0.11 12.3 11.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.19 EKX46742.1 - 0.018 13.0 4.5 0.022 12.7 4.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CALCOCO1 PF07888.11 EKX46742.1 - 0.018 13.9 8.3 0.031 13.2 8.3 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like MAD PF05557.13 EKX46742.1 - 0.02 13.3 9.6 0.032 12.6 9.6 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein YabA PF06156.13 EKX46742.1 - 0.02 15.5 11.2 0.66 10.6 11.2 2.6 1 1 0 1 1 1 0 Initiation control protein YabA Vps54_N PF10475.9 EKX46742.1 - 0.025 13.9 1.3 0.035 13.4 1.3 1.2 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex AP_endonuc_2_N PF07582.12 EKX46742.1 - 0.028 14.2 0.1 4.5 7.1 0.0 2.6 2 1 0 2 2 2 0 AP endonuclease family 2 C terminus Snapin_Pallidin PF14712.6 EKX46742.1 - 0.028 14.8 5.6 0.028 14.8 5.6 2.3 1 1 2 3 3 3 0 Snapin/Pallidin HlyD_2 PF12700.7 EKX46742.1 - 0.029 13.1 6.0 0.035 12.9 6.0 1.1 1 0 0 1 1 1 0 HlyD family secretion protein DUF4559 PF15112.6 EKX46742.1 - 0.029 14.1 4.5 0.044 13.5 4.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Lambda_tail_I PF06805.12 EKX46742.1 - 0.031 14.6 0.0 2.5 8.5 0.0 2.7 1 1 1 2 2 2 0 Bacteriophage lambda tail assembly protein I KxDL PF10241.9 EKX46742.1 - 0.031 14.5 7.9 1.1 9.6 0.8 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF5082 PF16888.5 EKX46742.1 - 0.032 14.5 5.2 0.072 13.4 5.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) FAM76 PF16046.5 EKX46742.1 - 0.033 13.6 5.6 0.045 13.1 5.6 1.1 1 0 0 1 1 1 0 FAM76 protein Peptidase_M75 PF09375.10 EKX46742.1 - 0.033 13.6 1.9 0.084 12.3 1.9 1.7 1 1 0 1 1 1 0 Imelysin DUF3450 PF11932.8 EKX46742.1 - 0.035 13.4 10.3 0.097 12.0 4.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Jnk-SapK_ap_N PF09744.9 EKX46742.1 - 0.037 14.3 9.5 0.062 13.5 9.5 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Nmad5 PF18757.1 EKX46742.1 - 0.037 14.2 5.0 0.23 11.6 5.0 2.4 1 1 0 1 1 1 0 Nucleotide modification associated domain 5 Ax_dynein_light PF10211.9 EKX46742.1 - 0.04 13.9 14.2 0.025 14.5 10.3 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain DUF4407 PF14362.6 EKX46742.1 - 0.041 13.2 6.2 0.15 11.3 6.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CorA PF01544.18 EKX46742.1 - 0.043 13.1 2.2 0.056 12.8 2.2 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HIP1_clath_bdg PF16515.5 EKX46742.1 - 0.043 14.4 14.9 0.17 12.5 5.1 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Sec34 PF04136.15 EKX46742.1 - 0.047 13.6 4.3 1.4 8.8 0.8 2.1 1 1 1 2 2 2 0 Sec34-like family GrpE PF01025.19 EKX46742.1 - 0.048 13.3 11.4 0.77 9.4 11.4 2.1 1 1 0 1 1 1 0 GrpE Nup88 PF10168.9 EKX46742.1 - 0.049 11.5 6.8 0.065 11.0 6.8 1.2 1 0 0 1 1 1 0 Nuclear pore component DASH_Dad2 PF08654.10 EKX46742.1 - 0.05 14.0 7.9 0.47 10.9 1.5 2.4 1 1 1 2 2 2 0 DASH complex subunit Dad2 T3SSipB PF16535.5 EKX46742.1 - 0.051 14.0 5.1 0.29 11.6 3.6 2.0 1 1 1 2 2 2 0 Type III cell invasion protein SipB HalX PF08663.10 EKX46742.1 - 0.057 13.7 2.6 0.43 10.9 0.2 2.8 1 1 3 4 4 2 0 HalX domain ADIP PF11559.8 EKX46742.1 - 0.057 13.5 9.6 0.23 11.6 3.2 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Dabb PF07876.12 EKX46742.1 - 0.058 14.0 3.5 4.9 7.8 0.4 2.4 1 1 1 2 2 2 0 Stress responsive A/B Barrel Domain Phage_GP20 PF06810.11 EKX46742.1 - 0.059 13.2 15.4 1.3 8.8 4.4 2.9 1 1 2 3 3 3 0 Phage minor structural protein GP20 Phage_GPO PF05929.11 EKX46742.1 - 0.06 13.0 7.8 0.15 11.7 7.8 1.7 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF5320 PF17253.2 EKX46742.1 - 0.065 14.3 8.1 2.8 9.0 0.3 2.8 1 1 2 3 3 3 0 Family of unknown function (DUF5320) Alpha-E PF04168.12 EKX46742.1 - 0.07 12.9 0.5 0.46 10.2 0.5 1.9 1 1 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. Syntaxin PF00804.25 EKX46742.1 - 0.071 12.8 9.6 0.9 9.2 1.0 2.3 1 1 1 2 2 2 0 Syntaxin HrpB7 PF09486.10 EKX46742.1 - 0.075 13.4 4.2 0.2 12.1 4.2 1.6 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) EMP24_GP25L PF01105.24 EKX46742.1 - 0.077 12.9 9.2 46 3.9 9.2 2.1 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD SKA1 PF07160.12 EKX46742.1 - 0.078 12.8 7.8 0.78 9.5 5.3 2.0 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 TMF_DNA_bd PF12329.8 EKX46742.1 - 0.083 12.9 15.7 0.64 10.1 4.5 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Cytochrom_B562 PF07361.11 EKX46742.1 - 0.085 13.5 11.2 2.3 8.9 6.5 2.2 1 1 1 2 2 2 0 Cytochrome b562 DUF4446 PF14584.6 EKX46742.1 - 0.086 12.8 8.0 1.6 8.7 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) KfrA_N PF11740.8 EKX46742.1 - 0.087 13.5 3.4 1.1 10.0 0.2 2.5 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term CENP-F_leu_zip PF10473.9 EKX46742.1 - 0.088 12.8 15.7 0.15 12.1 13.3 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MHCassoc_trimer PF08831.10 EKX46742.1 - 0.088 12.8 7.0 7.2 6.7 0.4 3.5 1 1 2 3 3 3 0 Class II MHC-associated invariant chain trimerisation domain DUF2730 PF10805.8 EKX46742.1 - 0.088 12.9 8.4 3.1 8.0 0.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) DUF4140 PF13600.6 EKX46742.1 - 0.1 13.1 4.1 2.1 8.8 0.6 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4164 PF13747.6 EKX46742.1 - 0.11 12.8 5.6 0.13 12.6 2.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) SpecificRecomb PF10136.9 EKX46742.1 - 0.11 10.7 2.3 0.32 9.2 2.4 1.6 1 1 0 1 1 1 0 Site-specific recombinase Fzo_mitofusin PF04799.13 EKX46742.1 - 0.12 12.0 8.2 0.59 9.7 3.1 2.7 1 1 2 3 3 3 0 fzo-like conserved region RmuC PF02646.16 EKX46742.1 - 0.12 11.5 9.9 0.74 8.9 2.4 2.2 1 1 1 2 2 2 0 RmuC family Tektin PF03148.14 EKX46742.1 - 0.12 11.1 12.1 0.36 9.5 12.1 1.6 1 1 0 1 1 1 0 Tektin family DUF4201 PF13870.6 EKX46742.1 - 0.13 12.0 12.2 0.22 11.3 12.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) V-SNARE_C PF12352.8 EKX46742.1 - 0.13 12.6 2.5 1.7 9.0 0.3 2.3 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EKX46742.1 - 0.13 12.2 2.3 1.2 9.0 0.8 2.2 1 1 1 2 2 2 0 Sec20 Prefoldin_3 PF13758.6 EKX46742.1 - 0.13 12.3 5.3 0.36 10.9 5.1 2.0 1 1 0 1 1 1 0 Prefoldin subunit Atg14 PF10186.9 EKX46742.1 - 0.13 11.3 5.1 0.33 10.0 5.2 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 VraX PF17412.2 EKX46742.1 - 0.13 11.9 0.0 10 5.8 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function HAP1_N PF04849.13 EKX46742.1 - 0.14 11.3 11.1 0.23 10.6 11.1 1.4 1 1 0 1 1 1 0 HAP1 N-terminal conserved region MbeD_MobD PF04899.12 EKX46742.1 - 0.16 12.1 2.0 5.4 7.2 0.4 2.5 1 1 1 2 2 2 0 MbeD/MobD like Fmp27_WPPW PF10359.9 EKX46742.1 - 0.19 10.6 6.3 0.29 9.9 6.3 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Spc24 PF08286.11 EKX46742.1 - 0.21 11.9 9.9 2 8.7 5.4 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 COG5 PF10392.9 EKX46742.1 - 0.22 11.7 1.6 0.51 10.5 0.3 1.8 1 1 1 2 2 2 0 Golgi transport complex subunit 5 GARP PF16731.5 EKX46742.1 - 0.22 11.2 4.3 3.1 7.4 0.5 2.3 1 1 1 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma Tmemb_cc2 PF10267.9 EKX46742.1 - 0.23 10.6 12.4 0.59 9.2 4.0 1.8 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein USP8_interact PF08941.10 EKX46742.1 - 0.23 11.2 6.9 0.5 10.2 1.5 2.1 1 1 1 2 2 2 0 USP8 interacting YtxH PF12732.7 EKX46742.1 - 0.24 11.9 7.9 58 4.3 7.9 2.5 1 1 0 1 1 1 0 YtxH-like protein End3 PF12761.7 EKX46742.1 - 0.29 11.3 10.6 2.4 8.3 1.7 2.0 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Fungal_TACC PF12709.7 EKX46742.1 - 0.3 11.6 10.9 0.85 10.1 2.3 2.3 1 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Spc29 PF17082.5 EKX46742.1 - 0.31 10.9 4.7 0.99 9.2 4.8 1.7 1 1 0 1 1 1 0 Spindle Pole Component 29 RasGAP_C PF03836.15 EKX46742.1 - 0.33 11.1 5.9 1.2 9.2 0.5 2.1 1 1 1 2 2 2 0 RasGAP C-terminus CAF-1_p150 PF11600.8 EKX46742.1 - 0.36 10.5 11.1 0.5 10.0 11.1 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FliD_N PF02465.18 EKX46742.1 - 0.36 11.5 4.0 1.3 9.8 1.0 2.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Fibritin_C PF07921.12 EKX46742.1 - 0.36 11.0 2.6 1.9 8.7 0.6 2.2 1 1 1 2 2 2 0 Fibritin C-terminal region ACCA PF03255.14 EKX46742.1 - 0.36 10.7 9.0 1.7 8.5 1.4 2.2 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit LMBR1 PF04791.16 EKX46742.1 - 0.38 9.6 0.5 0.45 9.4 0.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein BDV_P24 PF06595.11 EKX46742.1 - 0.38 10.6 2.0 2 8.2 0.3 1.9 1 1 1 2 2 2 0 Borna disease virus P24 protein KI67R PF08065.12 EKX46742.1 - 0.41 11.2 5.0 0.52 10.9 4.0 1.7 1 1 0 1 1 1 0 KI67R (NUC007) repeat TRAF_BIRC3_bd PF16673.5 EKX46742.1 - 0.41 10.5 3.1 13 5.6 0.3 2.6 2 1 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Trimer_CC PF08954.11 EKX46742.1 - 0.42 10.2 7.7 1.6 8.4 0.2 3.2 2 1 1 3 3 3 0 Trimerisation motif KASH_CCD PF14662.6 EKX46742.1 - 0.42 10.4 13.6 0.83 9.4 13.6 1.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Tup_N PF08581.10 EKX46742.1 - 0.43 10.9 13.3 12 6.2 1.2 3.1 1 1 2 3 3 3 0 Tup N-terminal ABC_tran_CTD PF16326.5 EKX46742.1 - 0.45 10.8 7.9 0.58 10.4 5.3 2.3 1 1 2 3 3 2 0 ABC transporter C-terminal domain Rootletin PF15035.6 EKX46742.1 - 0.46 10.5 10.3 1.4 8.9 7.5 2.0 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Cauli_AT PF03233.13 EKX46742.1 - 0.46 10.4 5.0 2.4 8.1 5.0 1.9 1 1 0 1 1 1 0 Aphid transmission protein CLZ PF16526.5 EKX46742.1 - 0.5 10.8 14.0 3.3 8.1 3.4 2.3 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels 5_nucleotid PF05761.14 EKX46742.1 - 0.53 9.1 7.1 0.18 10.7 1.1 2.0 1 1 1 2 2 2 0 5' nucleotidase family TSC22 PF01166.18 EKX46742.1 - 0.54 10.6 7.6 5.9 7.3 0.4 3.4 1 1 2 3 3 3 0 TSC-22/dip/bun family ORF6C PF10552.9 EKX46742.1 - 0.58 10.3 9.6 4.7 7.3 1.9 2.8 1 1 2 3 3 2 0 ORF6C domain DUF745 PF05335.13 EKX46742.1 - 0.67 9.6 6.1 2.5 7.8 5.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF745) APG6_N PF17675.1 EKX46742.1 - 0.68 10.5 12.2 0.46 11.0 8.3 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region UPF0449 PF15136.6 EKX46742.1 - 0.69 10.4 7.8 36 4.9 7.8 2.5 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 OmpH PF03938.14 EKX46742.1 - 0.71 10.2 13.8 0.24 11.7 5.8 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DASH_Dad3 PF08656.10 EKX46742.1 - 0.75 9.9 4.1 3 8.0 0.7 2.4 1 1 0 2 2 2 0 DASH complex subunit Dad3 Baculo_F PF12259.8 EKX46742.1 - 0.81 8.1 4.9 1.1 7.7 4.9 1.2 1 0 0 1 1 1 0 Baculovirus F protein CC2-LZ PF16516.5 EKX46742.1 - 0.88 10.0 12.1 0.55 10.6 2.9 2.3 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator IFT20 PF14931.6 EKX46742.1 - 0.88 9.7 8.8 6.9 6.9 2.7 2.2 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF2968 PF11180.8 EKX46742.1 - 0.89 9.2 6.9 7.8 6.1 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) CREPT PF16566.5 EKX46742.1 - 1.1 9.5 8.7 7.5 6.7 8.7 1.9 1 1 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour TSNAXIP1_N PF15739.5 EKX46742.1 - 1.1 9.6 8.4 7.9 6.9 7.4 2.3 1 1 0 1 1 1 0 Translin-associated factor X-interacting N-terminus DUF3740 PF12548.8 EKX46742.1 - 1.2 9.5 6.4 8.8 6.8 0.2 2.4 2 0 0 2 2 2 0 Sulfatase protein ApoC-I PF04691.12 EKX46742.1 - 1.3 9.0 6.1 2.4 8.1 0.8 3.2 1 1 2 3 3 2 0 Apolipoprotein C-I (ApoC-1) XhlA PF10779.9 EKX46742.1 - 1.3 9.3 16.2 7.3 6.9 6.9 3.3 1 1 2 3 3 3 0 Haemolysin XhlA CtIP_N PF10482.9 EKX46742.1 - 1.4 9.0 11.3 1.3 9.1 2.1 2.4 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain TMF_TATA_bd PF12325.8 EKX46742.1 - 1.4 9.1 15.0 7.1 6.9 15.3 1.9 1 1 1 2 2 1 0 TATA element modulatory factor 1 TATA binding Cnn_1N PF07989.11 EKX46742.1 - 1.5 9.0 15.1 1.3 9.2 2.0 2.3 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 LRRFIP PF09738.9 EKX46742.1 - 1.6 8.1 13.4 1.2 8.6 3.7 2.1 1 1 1 2 2 2 0 LRRFIP family CENP-H PF05837.12 EKX46742.1 - 1.8 9.0 10.0 17 5.9 9.5 2.2 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Sipho_Gp157 PF05565.11 EKX46742.1 - 1.8 8.5 10.6 3.9 7.5 10.5 1.6 1 1 0 1 1 1 0 Siphovirus Gp157 DUF2205 PF10224.9 EKX46742.1 - 1.9 8.6 8.7 3.7 7.6 2.0 2.4 1 1 1 2 2 2 0 Short coiled-coil protein DUF883 PF05957.13 EKX46742.1 - 1.9 9.1 6.4 9 7.0 3.8 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF641 PF04859.12 EKX46742.1 - 2.2 8.6 9.5 16 5.8 9.5 2.1 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF1515 PF07439.11 EKX46742.1 - 2.6 8.1 7.9 4.2 7.4 5.6 2.4 2 1 0 2 2 1 0 Protein of unknown function (DUF1515) TEX13 PF15186.6 EKX46742.1 - 2.8 7.6 8.5 6.1 6.5 1.2 2.1 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family PRKG1_interact PF15898.5 EKX46742.1 - 2.9 8.9 13.9 7.8 7.5 10.1 2.5 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DHR10 PF18595.1 EKX46742.1 - 2.9 8.0 13.4 3 7.9 2.9 2.5 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain ATG16 PF08614.11 EKX46742.1 - 3.2 8.0 13.1 2.1 8.5 2.9 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF4208 PF13907.6 EKX46742.1 - 3.2 8.2 7.6 28 5.2 0.4 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4208) DUF4795 PF16043.5 EKX46742.1 - 3.5 7.2 16.4 17 4.9 16.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) DMPK_coil PF08826.10 EKX46742.1 - 3.7 7.7 14.4 2.3 8.4 4.7 3.1 1 1 1 2 2 2 0 DMPK coiled coil domain like DUF4337 PF14235.6 EKX46742.1 - 4.7 7.3 7.0 16 5.6 3.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) FlxA PF14282.6 EKX46742.1 - 5 7.2 11.4 15 5.6 5.1 2.3 1 1 2 3 3 3 0 FlxA-like protein SLX9 PF15341.6 EKX46742.1 - 5.4 7.4 9.4 12 6.3 7.8 2.0 1 1 1 2 2 2 0 Ribosome biogenesis protein SLX9 Tho2 PF11262.8 EKX46742.1 - 5.6 6.1 10.5 4.3 6.5 2.9 2.0 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 PIEZO PF15917.5 EKX46742.1 - 6.1 6.3 10.7 9 5.7 3.2 2.1 1 1 1 2 2 2 0 Piezo Rbsn PF11464.8 EKX46742.1 - 6.4 6.6 12.9 5.6 6.8 0.2 4.0 4 1 1 5 5 3 0 Rabenosyn Rab binding domain Lipoprotein_20 PF13942.6 EKX46742.1 - 7.3 6.5 11.1 10 6.0 0.9 2.9 2 1 1 3 3 3 0 YfhG lipoprotein DUF3782 PF12644.7 EKX46742.1 - 7.4 6.8 11.1 16 5.8 1.9 3.2 2 1 1 3 3 2 0 Protein of unknown function (DUF3782) BST2 PF16716.5 EKX46742.1 - 8 7.1 14.3 8.4 7.1 2.4 2.8 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DUF5129 PF17173.4 EKX46743.1 - 0.0082 15.3 0.6 0.011 14.9 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5129) Mei5 PF10376.9 EKX46743.1 - 0.14 12.0 7.3 0.21 11.4 7.3 1.3 1 0 0 1 1 1 0 Double-strand recombination repair protein GBP_C PF02841.14 EKX46743.1 - 0.42 10.0 9.2 0.57 9.5 9.2 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain polyprenyl_synt PF00348.17 EKX46744.1 - 1.6e-57 194.5 0.0 2e-57 194.2 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Mpv17_PMP22 PF04117.12 EKX46745.1 - 5.4e-05 23.3 1.3 0.00014 22.1 0.6 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family WD40 PF00400.32 EKX46746.1 - 3.8e-19 68.7 17.4 6.8e-06 26.7 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX46746.1 - 1.5e-09 38.0 0.0 0.036 14.4 0.0 3.9 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EKX46746.1 - 0.00015 21.7 0.0 0.061 13.2 0.0 3.5 3 1 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EKX46746.1 - 0.0052 16.7 0.8 0.71 9.9 0.3 2.9 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.7 EKX46746.1 - 0.012 15.5 0.5 23 4.9 0.0 3.3 3 0 0 3 3 3 0 Transcription factor IIIC subunit delta N-term Aminotran_5 PF00266.19 EKX46750.1 - 8.9e-19 67.7 0.0 1.1e-16 60.8 0.0 2.0 2 0 0 2 2 2 2 Aminotransferase class-V cNMP_binding PF00027.29 EKX46752.1 - 1.1e-05 25.4 0.0 3.7e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain VCBS PF13517.6 EKX46752.1 - 0.11 13.1 0.0 2.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PHM7_cyt PF14703.6 EKX46752.1 - 0.3 11.3 2.9 0.92 9.7 2.8 1.9 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter GlnE PF03710.15 EKX46752.1 - 0.92 8.9 5.0 1.5 8.2 5.0 1.3 1 0 0 1 1 1 0 Glutamate-ammonia ligase adenylyltransferase SNARE_assoc PF09335.11 EKX46753.1 - 8.2e-18 65.0 5.9 1.1e-17 64.7 3.0 2.2 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF4611 PF15387.6 EKX46753.1 - 0.033 14.4 1.4 0.099 12.9 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF3727 PF12527.8 EKX46753.1 - 0.18 12.0 4.4 0.37 11.0 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3727) Dicty_REP PF05086.12 EKX46753.1 - 6.2 4.7 4.8 8.5 4.2 4.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Bestrophin PF01062.21 EKX46754.1 - 1.9e-27 96.4 1.0 4e-27 95.4 1.0 1.4 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel CodY PF06018.14 EKX46755.1 - 0.027 14.0 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 CodY GAF-like domain Aa_trans PF01490.18 EKX46757.1 - 6.9e-53 179.8 25.2 9.1e-53 179.4 25.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Diphthami_syn_2 PF01902.17 EKX46758.1 - 6.9e-35 120.5 0.0 2.2e-34 118.9 0.0 1.7 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 EKX46758.1 - 4e-30 104.3 0.0 8.8e-21 74.2 0.0 2.5 2 0 0 2 2 2 2 Endoribonuclease L-PSP QueC PF06508.13 EKX46758.1 - 0.053 13.0 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC RCC1 PF00415.18 EKX46759.1 - 4.8e-29 100.7 25.0 4.1e-07 30.5 0.0 7.7 8 1 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat PH PF00169.29 EKX46759.1 - 1.3e-16 61.0 0.2 1.3e-13 51.3 0.0 2.6 2 0 0 2 2 2 2 PH domain RCC1_2 PF13540.6 EKX46759.1 - 1.5e-15 56.6 27.0 0.0017 18.1 3.2 6.4 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Trypan_PARP PF05887.11 EKX46759.1 - 0.00057 19.9 3.6 0.00057 19.9 3.6 4.3 3 1 0 3 3 3 1 Procyclic acidic repetitive protein (PARP) CCDC53 PF10152.9 EKX46759.1 - 0.018 15.5 2.3 0.018 15.5 2.3 4.8 3 1 0 3 3 3 0 Subunit CCDC53 of WASH complex PH_9 PF15410.6 EKX46759.1 - 0.045 14.1 4.2 1 9.7 0.1 3.4 3 1 0 3 3 3 0 Pleckstrin homology domain I_LWEQ PF01608.17 EKX46760.1 - 0.022 15.0 0.4 0.029 14.6 0.4 1.3 1 1 0 1 1 1 0 I/LWEQ domain DUF713 PF05218.14 EKX46760.1 - 0.08 12.7 0.1 0.1 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF713) Ank_4 PF13637.6 EKX46761.1 - 4.7e-23 81.3 0.0 1.1e-07 32.3 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX46761.1 - 2.1e-19 69.9 0.1 8.6e-12 45.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX46761.1 - 2.2e-18 64.4 0.0 0.00028 21.1 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 EKX46761.1 - 1.8e-14 53.4 0.0 0.00017 21.9 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EKX46761.1 - 7.9e-12 45.2 0.1 1.3e-06 28.6 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) LRR_6 PF13516.6 EKX46762.1 - 3e-15 54.9 3.9 0.00068 19.5 0.2 4.2 4 0 0 4 4 4 4 Leucine Rich repeat LRR_4 PF12799.7 EKX46762.1 - 0.0045 17.4 1.7 0.0045 17.4 1.7 2.9 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX46762.1 - 0.037 14.5 7.5 54 4.9 2.9 5.0 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 EKX46762.1 - 0.25 11.1 8.0 36 4.2 3.1 4.0 1 1 2 3 3 3 0 Leucine rich repeat Glyco_trans_2_3 PF13632.6 EKX46763.1 - 2.9e-10 40.4 4.7 5.5e-10 39.5 4.7 1.4 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EKX46763.1 - 5.5e-05 23.2 0.2 0.00027 20.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EKX46763.1 - 0.16 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 FKBP_C PF00254.28 EKX46764.1 - 2.6e-07 30.9 0.0 8.6e-07 29.2 0.0 2.1 2 1 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Lig_chan PF00060.26 EKX46765.1 - 4.3e-11 42.9 0.2 1e-10 41.6 0.2 1.7 1 0 0 1 1 1 1 Ligand-gated ion channel DUF4199 PF13858.6 EKX46765.1 - 0.01 16.2 0.4 0.01 16.2 0.4 2.4 3 1 1 4 4 4 0 Protein of unknown function (DUF4199) Ion_trans PF00520.31 EKX46765.1 - 0.12 11.6 1.1 1.1 8.4 1.9 2.0 2 0 0 2 2 2 0 Ion transport protein Ion_trans_2 PF07885.16 EKX46765.1 - 0.36 10.8 9.8 0.023 14.6 4.5 1.8 2 0 0 2 2 2 0 Ion channel Lin-8 PF03353.15 EKX46765.1 - 1.5 8.3 11.3 1.9 8.0 11.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MAP7 PF05672.11 EKX46765.1 - 4.4 7.0 13.9 6 6.5 13.9 1.1 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Fasciclin PF02469.22 EKX46766.1 - 0.1 12.8 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Fasciclin domain TPR_12 PF13424.6 EKX46768.1 - 4.6e-35 119.7 17.1 1.2e-07 31.9 0.3 7.5 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 EKX46768.1 - 4.1e-10 39.0 14.6 0.034 14.3 0.1 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX46768.1 - 9.2e-08 31.7 13.5 0.03 14.2 0.0 6.7 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX46768.1 - 1.9e-06 28.3 1.4 2.1 8.9 0.0 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat AAA_16 PF13191.6 EKX46768.1 - 2.6e-05 24.7 8.4 3.6e-05 24.2 1.8 4.0 3 1 0 3 3 3 1 AAA ATPase domain MORN PF02493.20 EKX46768.1 - 0.00025 20.8 4.5 0.00051 19.8 2.6 2.5 2 0 0 2 2 2 1 MORN repeat Rad17 PF03215.15 EKX46768.1 - 0.0014 18.6 0.0 0.0033 17.4 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain TPR_4 PF07721.14 EKX46768.1 - 0.0018 18.7 5.8 0.037 14.7 0.2 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat SPO22 PF08631.10 EKX46768.1 - 0.0025 17.4 14.7 0.09 12.2 0.5 4.4 3 1 1 4 4 4 2 Meiosis protein SPO22/ZIP4 like NACHT PF05729.12 EKX46768.1 - 0.0051 16.7 1.9 0.013 15.4 0.0 2.6 3 0 0 3 3 3 1 NACHT domain TPR_7 PF13176.6 EKX46768.1 - 0.0073 16.3 12.5 3 8.1 0.1 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat AAA_22 PF13401.6 EKX46768.1 - 0.0097 16.2 0.0 0.045 14.0 0.0 2.2 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EKX46768.1 - 0.01 15.8 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TPR_16 PF13432.6 EKX46768.1 - 0.011 16.4 1.0 12 6.6 0.2 4.3 4 1 0 4 4 2 0 Tetratricopeptide repeat AAA_25 PF13481.6 EKX46768.1 - 0.015 14.9 0.1 0.36 10.4 0.1 3.2 2 1 0 2 2 2 0 AAA domain TPR_14 PF13428.6 EKX46768.1 - 0.024 15.4 10.4 0.46 11.4 0.2 6.1 8 0 0 8 8 3 0 Tetratricopeptide repeat AAA_7 PF12775.7 EKX46768.1 - 0.064 12.8 0.0 0.21 11.1 0.0 1.9 1 0 0 1 1 1 0 P-loop containing dynein motor region Coatomer_E PF04733.14 EKX46768.1 - 0.077 12.4 4.7 1.5 8.2 0.0 3.5 4 0 0 4 4 4 0 Coatomer epsilon subunit T2SSE PF00437.20 EKX46768.1 - 0.097 11.7 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein TPR_8 PF13181.6 EKX46768.1 - 0.1 12.8 18.2 0.3 11.4 0.1 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX46768.1 - 0.13 12.5 12.9 5 7.4 0.0 5.9 5 1 0 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EKX46768.1 - 0.15 12.8 10.1 8.7 7.2 0.2 6.4 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 EKX46768.1 - 0.15 12.5 2.1 1.1e+02 3.5 0.0 4.6 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EKX46768.1 - 0.75 9.7 17.9 8.4 6.4 0.1 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat OB_aCoA_assoc PF01796.17 EKX46768.1 - 0.82 9.7 2.2 3.6 7.7 0.2 2.5 2 0 0 2 2 2 0 DUF35 OB-fold domain, acyl-CoA-associated Sushi PF00084.20 EKX46769.1 - 1.4e-13 51.2 10.5 0.0017 18.9 0.1 4.8 4 0 0 4 4 4 4 Sushi repeat (SCR repeat) PCSK9_C3 PF18463.1 EKX46769.1 - 0.0009 19.4 0.2 1.1 9.6 0.0 4.3 4 0 0 4 4 4 1 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain NicO PF03824.16 EKX46769.1 - 0.22 10.8 0.0 0.39 10.0 0.0 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein Toxin_TOLIP PF00087.21 EKX46769.1 - 3.6 7.9 13.4 1.6 9.0 0.2 3.7 3 0 0 3 3 3 0 Snake toxin and toxin-like protein Anoctamin PF04547.12 EKX46770.1 - 5.8e-68 229.8 15.5 7.8e-68 229.3 15.5 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 EKX46770.1 - 0.00067 19.5 0.2 0.0013 18.5 0.2 1.5 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Guanylate_cyc PF00211.20 EKX46771.1 - 5.6e-47 159.7 0.2 6.2e-47 159.6 0.2 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain AP4E_app_platf PF14807.6 EKX46771.1 - 0.15 12.5 0.0 0.58 10.5 0.0 1.8 1 1 1 2 2 2 0 Adaptin AP4 complex epsilon appendage platform Porphobil_deamC PF03900.15 EKX46772.1 - 0.078 13.4 0.1 0.11 12.9 0.1 1.2 1 0 0 1 1 1 0 Porphobilinogen deaminase, C-terminal domain Dpy-30 PF05186.13 EKX46773.1 - 0.013 15.2 0.0 0.074 12.8 0.0 2.0 2 0 0 2 2 2 0 Dpy-30 motif CS PF04969.16 EKX46774.1 - 5e-12 46.7 0.4 9.9e-12 45.7 0.4 1.4 1 0 0 1 1 1 1 CS domain PIH1_CS PF18201.1 EKX46774.1 - 0.057 13.8 0.0 0.097 13.1 0.0 1.4 1 0 0 1 1 1 0 PIH1 CS-like domain RCC1 PF00415.18 EKX46775.1 - 2.2e-68 226.7 39.0 3.2e-15 56.5 0.7 7.3 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX46775.1 - 3e-47 157.5 43.6 7.8e-11 41.5 1.4 6.2 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Lactamase_B PF00753.27 EKX46775.1 - 0.23 11.4 0.7 0.38 10.7 0.0 1.6 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Antimicrobial_1 PF08018.11 EKX46776.1 - 0.073 13.2 2.8 50 4.2 0.1 4.2 5 0 0 5 5 5 0 Frog antimicrobial peptide T3SS_ExsE PF18286.1 EKX46776.1 - 0.57 10.2 8.3 17 5.5 0.0 4.6 2 2 3 5 5 5 0 Type III secretion system ExsE SHOCT PF09851.9 EKX46779.1 - 0.0048 16.6 2.4 1.6 8.6 0.2 2.5 2 0 0 2 2 2 2 Short C-terminal domain Terminase_GpA PF05876.12 EKX46779.1 - 0.005 15.4 1.2 0.006 15.2 0.6 1.3 2 0 0 2 2 2 1 Phage terminase large subunit (GpA) DUF1731 PF08338.11 EKX46780.1 - 2.4e-18 65.7 0.4 5.1e-18 64.6 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 EKX46780.1 - 3.8e-06 26.5 0.0 0.00032 20.2 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family HMG_box PF00505.19 EKX46781.1 - 1.5e-31 108.6 17.9 2.3e-18 66.3 4.5 2.8 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 EKX46781.1 - 3.1e-23 82.2 16.9 2.5e-14 53.6 3.4 2.5 2 0 0 2 2 2 2 HMG-box domain Protamine_like PF06382.11 EKX46781.1 - 0.024 14.8 4.2 0.074 13.2 1.8 2.0 1 1 1 2 2 2 0 Protamine and protamine like Ran-binding PF05508.11 EKX46781.1 - 0.15 11.0 3.5 0.092 11.7 0.2 1.9 1 1 1 2 2 2 0 RanGTP-binding protein YABBY PF04690.13 EKX46781.1 - 9.2 6.8 15.1 0.049 14.2 3.1 2.4 1 1 2 3 3 3 0 YABBY protein Kelch_3 PF13415.6 EKX46782.1 - 1.2e-21 76.5 3.4 1.1e-07 32.0 0.3 5.8 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 EKX46782.1 - 2.8e-21 74.6 8.0 3.3e-08 33.2 0.2 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 EKX46782.1 - 5.1e-21 74.2 3.7 2.7e-07 30.4 0.1 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 EKX46782.1 - 6.1e-19 67.3 4.6 1.1e-07 31.3 0.1 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 EKX46782.1 - 1.1e-18 66.9 3.4 2.9e-05 24.0 0.1 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EKX46782.1 - 2.8e-09 36.9 5.1 0.0085 16.4 0.0 4.5 5 0 0 5 5 5 2 Kelch motif Ephrin_rec_like PF07699.13 EKX46783.1 - 6e-41 138.0 80.7 6.1e-10 38.7 6.5 8.1 2 1 6 8 8 8 8 Putative ephrin-receptor like NCD3G PF07562.14 EKX46783.1 - 3.7e-14 52.4 53.2 0.0093 15.9 1.0 7.4 1 1 6 9 9 9 9 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX46783.1 - 1.5e-12 47.7 55.1 0.015 15.7 1.1 9.1 1 1 12 13 13 13 12 TNFR/NGFR cysteine-rich region VSP PF03302.13 EKX46783.1 - 0.0054 15.6 69.8 0.33 9.8 19.7 3.5 1 1 2 3 3 3 3 Giardia variant-specific surface protein Zn_ribbon_SprT PF17283.2 EKX46783.1 - 0.053 13.4 0.3 0.053 13.4 0.3 6.9 6 3 1 7 7 7 0 SprT-like zinc ribbon domain DUF2318 PF10080.9 EKX46783.1 - 4.1 7.6 41.1 0.48 10.6 2.6 5.5 1 1 3 5 5 5 0 Predicted membrane protein (DUF2318) Pkinase_Tyr PF07714.17 EKX46784.1 - 2.1e-41 141.9 0.0 2.4e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX46784.1 - 4.5e-25 88.5 0.0 5.7e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EKX46784.1 - 0.03 13.6 0.2 0.07 12.4 0.2 1.6 1 1 0 1 1 1 0 Kinase-like DUF5478 PF17572.2 EKX46784.1 - 0.089 12.9 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5478) 2_5_RNA_ligase2 PF13563.6 EKX46785.1 - 9.7e-34 116.5 0.8 1.2e-33 116.1 0.8 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Complex1_LYR_2 PF13233.6 EKX46786.1 - 2.1e-17 63.6 3.0 3.2e-17 63.1 3.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EKX46786.1 - 3.9e-07 30.0 0.2 3.9e-07 30.0 0.2 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Arc_PepC PF06819.11 EKX46786.1 - 0.019 15.1 0.4 0.023 14.8 0.4 1.2 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain Complex1_LYR_1 PF13232.6 EKX46786.1 - 0.034 14.7 0.3 0.052 14.2 0.3 1.5 1 1 0 1 1 1 0 Complex1_LYR-like Pkinase_Tyr PF07714.17 EKX46787.1 - 1.4e-39 135.9 0.0 1.6e-39 135.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX46787.1 - 2.7e-24 86.0 0.0 3e-24 85.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EKX46787.1 - 0.021 14.2 0.2 0.046 13.0 0.2 1.4 1 1 0 1 1 1 0 Kinase-like DUF5478 PF17572.2 EKX46787.1 - 0.056 13.5 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5478) Ephrin_rec_like PF07699.13 EKX46788.1 - 2.8e-56 187.1 146.2 9.9e-10 38.0 4.6 14.3 1 1 15 16 16 16 14 Putative ephrin-receptor like NCD3G PF07562.14 EKX46788.1 - 2e-19 69.3 101.8 0.0032 17.4 4.9 11.7 3 3 8 13 13 13 13 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX46788.1 - 9.3e-16 57.9 91.2 0.05 14.0 0.2 15.4 5 2 9 17 17 17 13 TNFR/NGFR cysteine-rich region Furin-like_2 PF15913.5 EKX46788.1 - 0.0002 21.5 63.9 0.00082 19.5 5.8 7.2 1 1 6 7 7 7 3 Furin-like repeat, cysteine-rich VSP PF03302.13 EKX46788.1 - 0.003 16.5 12.9 0.003 16.5 12.9 5.9 1 1 5 6 6 6 4 Giardia variant-specific surface protein CSN4_RPN5_eIF3a PF18420.1 EKX46788.1 - 8.5 6.6 6.5 34 4.7 0.7 2.3 2 0 0 2 2 2 0 CSN4/RPN5/eIF3a helix turn helix domain LMWPc PF01451.21 EKX46789.1 - 1.3e-18 67.8 0.0 1.9e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Ank_4 PF13637.6 EKX46790.1 - 1.7e-27 95.4 2.7 6.8e-10 39.3 0.5 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX46790.1 - 4.7e-19 68.8 0.1 4.9e-10 39.9 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX46790.1 - 4.5e-12 45.0 0.2 0.12 12.9 0.2 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EKX46790.1 - 9.8e-12 44.9 4.9 1.9e-05 24.9 0.4 3.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX46790.1 - 2.5e-11 43.5 4.0 5.2e-05 23.5 1.7 4.0 4 0 0 4 4 4 2 Ankyrin repeat HCV_NS5a_C PF12941.7 EKX46790.1 - 0.01 15.7 1.4 0.018 14.9 1.4 1.3 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region Cupin_8 PF13621.6 EKX46791.1 - 2.2e-19 70.2 1.3 2.9e-19 69.8 1.3 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EKX46791.1 - 5.8e-07 29.3 0.7 1.1e-05 25.1 0.0 2.4 3 0 0 3 3 3 1 Cupin superfamily protein JmjC PF02373.22 EKX46791.1 - 8.1e-05 23.0 0.8 0.0002 21.7 0.8 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EKX46791.1 - 0.00058 19.5 0.2 0.0078 15.9 0.0 2.3 2 0 0 2 2 2 1 Cupin domain RL11D PF11088.8 EKX46792.1 - 0.068 13.5 1.2 0.18 12.1 1.2 1.7 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 DUF3767 PF12597.8 EKX46793.1 - 5e-05 23.0 0.3 8.9e-05 22.3 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) DUF5008 PF16400.5 EKX46794.1 - 0.6 10.2 2.6 0.66 10.1 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5008) TPR_11 PF13414.6 EKX46795.1 - 0.047 13.4 0.1 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 TPR repeat Arm PF00514.23 EKX46796.1 - 1.8e-36 123.1 19.6 2e-10 40.3 0.0 8.8 9 0 0 9 9 8 6 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EKX46796.1 - 1.2e-18 65.6 3.1 0.00037 20.5 0.0 6.9 6 0 0 6 6 6 4 HEAT repeat Cnd1 PF12717.7 EKX46796.1 - 4.6e-14 52.8 0.1 0.0021 18.1 0.1 4.3 2 2 3 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EKX46796.1 - 8e-14 51.8 12.2 0.0034 17.7 0.2 5.2 3 2 2 5 5 5 4 HEAT repeats HEAT_EZ PF13513.6 EKX46796.1 - 1.1e-10 41.7 18.7 0.00063 20.2 0.8 6.6 4 1 3 7 7 7 4 HEAT-like repeat DNA_alkylation PF08713.11 EKX46796.1 - 6.9e-07 29.2 0.1 0.87 9.3 0.1 4.3 2 1 2 4 4 4 2 DNA alkylation repair enzyme Adaptin_N PF01602.20 EKX46796.1 - 8.6e-07 27.9 2.0 0.042 12.4 0.3 4.1 2 2 1 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.8 EKX46796.1 - 4.3e-06 26.5 0.0 0.036 13.6 0.0 2.8 2 0 0 2 2 2 2 CLASP N terminal CHASE6_C PF17150.4 EKX46796.1 - 1.4e-05 25.6 0.1 22 5.8 0.0 5.8 4 1 1 5 5 5 0 C-terminal domain of two-partite extracellular sensor domain RICTOR_N PF14664.6 EKX46796.1 - 0.0011 18.0 0.1 0.049 12.6 0.0 2.6 1 1 1 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term Arm_2 PF04826.13 EKX46796.1 - 0.0042 16.6 0.1 3.3 7.1 0.0 3.4 2 2 1 3 3 3 1 Armadillo-like Proteasom_PSMB PF10508.9 EKX46796.1 - 0.0056 15.2 5.0 0.025 13.1 0.4 3.0 2 1 0 3 3 3 1 Proteasome non-ATPase 26S subunit Mo25 PF08569.11 EKX46796.1 - 0.0066 15.9 0.1 0.29 10.4 0.0 2.7 2 1 1 3 3 3 1 Mo25-like V-ATPase_H_C PF11698.8 EKX46796.1 - 0.01 15.9 0.4 5.8 7.1 0.2 3.6 3 1 0 3 3 3 0 V-ATPase subunit H Atx10homo_assoc PF09759.9 EKX46796.1 - 0.012 15.6 0.9 2.3 8.3 0.2 3.5 3 1 2 5 5 4 0 Spinocerebellar ataxia type 10 protein domain RICTOR_V PF14668.6 EKX46796.1 - 0.017 15.3 0.0 4.2 7.7 0.0 3.7 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 Vac14_Fab1_bd PF12755.7 EKX46796.1 - 0.023 15.3 0.2 0.48 11.1 0.1 3.2 2 1 1 3 3 2 0 Vacuolar 14 Fab1-binding region CelTOS PF18659.1 EKX46796.1 - 0.054 13.9 0.6 14 6.2 0.0 3.0 2 1 0 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites HIRAN PF08797.11 EKX46796.1 - 0.1 12.6 0.0 5.4 7.0 0.0 2.6 2 0 0 2 2 2 0 HIRAN domain API5 PF05918.11 EKX46796.1 - 0.39 9.5 1.6 2.6 6.8 0.0 2.5 2 1 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) SRP54 PF00448.22 EKX46799.1 - 1.3e-36 126.1 0.6 9.5e-23 80.8 0.2 3.0 2 1 0 2 2 2 2 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EKX46799.1 - 5.7e-18 65.4 1.1 9.6e-17 61.4 1.0 2.6 2 0 0 2 2 2 1 Signal peptide binding domain SRP54_N PF02881.19 EKX46799.1 - 1.6e-17 63.5 0.7 6.6e-17 61.5 0.7 2.1 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain Herpes_capsid PF06112.11 EKX46799.1 - 0.051 13.6 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Pinin_SDK_memA PF04696.13 EKX46799.1 - 0.12 12.5 15.0 0.23 11.5 15.0 1.4 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region TMEM214 PF10151.9 EKX46799.1 - 0.3 9.5 4.7 0.45 8.9 4.7 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DUF2722 PF10846.8 EKX46799.1 - 0.85 8.5 11.5 1.4 7.8 11.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Med26_C PF15693.5 EKX46799.1 - 1.8 8.7 9.7 0.31 11.2 6.0 1.6 2 0 0 2 2 2 0 Mediator complex subunit 26 C-terminal Roughex PF06020.11 EKX46799.1 - 2.7 7.0 8.4 4.2 6.4 8.4 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Spt20 PF12090.8 EKX46799.1 - 3.8 7.0 14.2 6.5 6.3 14.2 1.3 1 0 0 1 1 1 0 Spt20 family RVT_1 PF00078.27 EKX46800.1 - 1.1e-14 54.5 0.0 4.7e-11 42.6 0.0 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Ank_2 PF12796.7 EKX46802.1 - 4.1e-43 145.9 0.0 3.8e-08 33.8 0.0 5.0 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX46802.1 - 2.1e-31 107.9 0.0 2e-05 25.1 0.0 5.9 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX46802.1 - 2.5e-24 85.0 1.3 0.00069 19.9 0.0 7.7 4 3 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX46802.1 - 4.9e-20 69.5 0.0 0.066 13.8 0.0 8.9 9 0 0 9 9 9 5 Ankyrin repeat Ank PF00023.30 EKX46802.1 - 4.9e-09 36.2 0.1 19 5.9 0.0 7.4 9 0 0 9 9 9 0 Ankyrin repeat Ins_beta PF03488.14 EKX46802.1 - 0.00025 21.0 14.3 28 4.8 0.1 7.5 8 0 0 8 8 8 0 Nematode insulin-related peptide beta type VHS PF00790.19 EKX46802.1 - 0.013 15.3 1.9 79 3.1 0.0 5.1 6 0 0 6 6 6 0 VHS domain TolA_bind_tri PF16331.5 EKX46802.1 - 0.032 14.3 0.1 38 4.5 0.0 4.1 5 0 0 5 5 5 0 TolA binding protein trimerisation DUF5642 PF18702.1 EKX46802.1 - 0.12 12.1 5.5 4.1 7.1 0.2 3.5 2 2 2 4 4 4 0 Domain of unknown function (DUF5642) ShK PF01549.24 EKX46802.1 - 0.18 12.4 10.9 64 4.2 0.0 6.0 6 0 0 6 6 6 0 ShK domain-like Herpes_UL33 PF03581.13 EKX46802.1 - 0.21 12.0 1.2 7.4 7.0 0.1 3.2 3 1 0 3 3 3 0 Herpesvirus UL33-like protein FANCI_S3 PF14677.6 EKX46802.1 - 0.24 11.1 0.0 10 5.8 0.0 3.1 2 2 1 3 3 3 0 FANCI solenoid 3 zf-C4 PF00105.18 EKX46804.1 - 0.18 12.3 1.0 0.4 11.2 1.0 1.6 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) Ephrin_rec_like PF07699.13 EKX46805.1 - 0.0045 16.7 2.9 0.0045 16.7 2.9 8.9 7 3 2 9 9 9 4 Putative ephrin-receptor like zf-ZPR1 PF03367.13 EKX46806.1 - 1.4e-11 44.5 0.1 3.4e-11 43.2 0.0 1.7 2 0 0 2 2 2 1 ZPR1 zinc-finger domain DUF5636 PF18686.1 EKX46806.1 - 0.057 13.6 0.1 0.15 12.3 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5636) HTH_40 PF14493.6 EKX46806.1 - 0.06 13.8 0.1 0.18 12.3 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain PSII_Pbs27 PF13326.6 EKX46806.1 - 0.076 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Photosystem II Pbs27 Ion_trans_2 PF07885.16 EKX46808.1 - 8.5e-12 44.9 4.9 2.4e-11 43.4 4.9 1.7 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EKX46808.1 - 4.9e-05 22.7 6.4 7.3e-05 22.1 6.4 1.2 1 0 0 1 1 1 1 Ion transport protein DUF4477 PF14780.6 EKX46808.1 - 0.024 14.3 0.9 0.063 12.9 0.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) Mg_chelatase PF01078.21 EKX46809.1 - 0.0088 15.4 0.0 0.01 15.2 0.0 1.1 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EKX46809.1 - 0.042 13.6 0.0 0.042 13.6 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein RHSP PF07999.11 EKX46809.1 - 0.071 11.9 0.0 0.071 11.9 0.0 1.0 1 0 0 1 1 1 0 Retrotransposon hot spot protein MeaB PF03308.16 EKX46809.1 - 0.18 10.8 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MscS_porin PF12795.7 EKX46810.1 - 1.3e-06 28.2 3.6 2.9e-05 23.8 2.8 2.1 1 1 1 2 2 2 2 Mechanosensitive ion channel porin domain Spc7 PF08317.11 EKX46810.1 - 0.0001 21.3 15.1 0.042 12.7 3.2 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein DUF812 PF05667.11 EKX46810.1 - 0.022 13.7 14.0 0.038 12.9 14.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) FlaC_arch PF05377.11 EKX46810.1 - 0.053 13.9 0.5 0.36 11.3 0.1 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Laminin_II PF06009.12 EKX46810.1 - 0.095 12.7 5.8 0.091 12.8 2.9 2.2 1 1 1 2 2 2 0 Laminin Domain II Coa1 PF08695.10 EKX46810.1 - 0.13 12.0 1.0 5.4 6.8 0.9 2.3 2 0 0 2 2 2 0 Cytochrome oxidase complex assembly protein 1 DUF4715 PF15835.5 EKX46810.1 - 0.35 10.9 9.0 1.4 8.9 7.6 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4715) ZapB PF06005.12 EKX46810.1 - 0.47 10.9 13.9 3.9 8.0 9.0 2.9 1 1 1 2 2 2 0 Cell division protein ZapB ATG16 PF08614.11 EKX46810.1 - 0.49 10.6 13.0 21 5.2 13.0 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 EKX46810.1 - 0.88 8.9 10.0 1.5 8.1 10.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 EKX46810.1 - 0.97 9.5 12.9 0.19 11.8 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 EKX46810.1 - 1.8 9.1 10.1 81 3.8 10.0 2.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein CCDC-167 PF15188.6 EKX46810.1 - 2.1 8.8 6.8 28 5.2 6.8 2.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 HrpB7 PF09486.10 EKX46810.1 - 2.5 8.5 7.5 1.6 9.1 0.1 2.6 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) STAR_dimer PF16544.5 EKX46810.1 - 2.9 7.5 9.9 18 5.0 0.7 3.7 2 1 1 3 3 3 0 Homodimerisation region of STAR domain protein UPF0242 PF06785.11 EKX46810.1 - 6.3 6.9 18.8 24 5.0 18.8 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AAA_12 PF13087.6 EKX46811.1 - 6.6e-25 87.9 0.4 7.3e-25 87.8 0.4 1.1 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EKX46811.1 - 0.00013 21.7 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EKX46811.1 - 0.088 12.5 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase HECT PF00632.25 EKX46812.1 - 6.1e-14 52.2 0.0 9.7e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SHIPPO-rpt PF07004.12 EKX46812.1 - 1.8e-09 38.0 16.9 2.2 9.4 0.1 10.2 12 0 0 12 12 12 3 Sperm-tail PG-rich repeat PDZ PF00595.24 EKX46812.1 - 0.00051 20.3 0.1 0.0012 19.2 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX46812.1 - 0.0029 17.4 0.0 0.0074 16.1 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Peptidase_M17 PF00883.21 EKX46813.1 - 7.5e-93 311.2 0.0 8.8e-93 311.0 0.0 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain TEX13 PF15186.6 EKX46815.1 - 0.39 10.4 2.9 1 9.0 2.9 1.7 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family PSI PF01437.25 EKX46815.1 - 4.6 7.9 18.7 0.097 13.2 10.8 2.3 3 0 0 3 3 3 0 Plexin repeat Keratin_B2_2 PF13885.6 EKX46816.1 - 2.2e-08 33.9 23.1 0.017 15.1 3.5 3.4 1 1 2 3 3 3 3 Keratin, high sulfur B2 protein HC2 PF07382.11 EKX46816.1 - 0.006 16.7 0.0 0.0083 16.2 0.0 1.2 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Keratin_B2 PF01500.17 EKX46816.1 - 0.099 12.6 24.8 3.7e+02 1.0 24.8 2.9 1 1 0 1 1 1 0 Keratin, high sulfur B2 protein Ank_5 PF13857.6 EKX46817.1 - 1.5e-13 50.7 0.7 2.9e-09 37.0 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX46817.1 - 3.9e-13 49.2 0.7 2.3e-05 24.7 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EKX46817.1 - 1.5e-12 47.9 0.0 1.7e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX46817.1 - 2.4e-10 39.7 0.0 0.00081 19.7 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EKX46817.1 - 2.7e-10 40.6 0.1 1e-08 35.6 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Gelsolin PF00626.22 EKX46818.1 - 2.4e-40 136.3 0.1 3.1e-09 36.6 0.0 6.5 6 0 0 6 6 6 6 Gelsolin repeat WD40 PF00400.32 EKX46819.1 - 2.9e-15 56.4 0.6 0.00087 20.1 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF1295 PF06966.12 EKX46820.1 - 2.6e-80 269.3 4.0 3.3e-80 269.0 4.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 EKX46820.1 - 1.9e-07 31.2 0.8 1.9e-07 31.2 0.8 2.3 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ERG4_ERG24 PF01222.17 EKX46820.1 - 0.00013 20.8 1.7 0.0013 17.6 1.7 2.2 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.13 EKX46820.1 - 0.00025 21.4 0.1 0.00025 21.4 0.1 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 EKX46820.1 - 0.0003 21.2 0.1 0.00083 19.7 0.1 1.8 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Ank_2 PF12796.7 EKX46821.1 - 2.4e-27 95.3 0.3 7e-16 58.6 0.2 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX46821.1 - 7.6e-25 87.0 2.7 3.2e-08 33.9 0.0 4.3 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EKX46821.1 - 5.7e-24 83.5 7.9 1.2e-07 31.9 0.0 5.6 5 1 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EKX46821.1 - 6.4e-23 78.4 1.0 4.7e-06 26.5 0.0 5.5 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EKX46821.1 - 1.9e-21 75.8 1.8 6.8e-08 32.6 0.0 3.7 3 1 0 3 3 3 3 Ankyrin repeats (many copies) DUF3915 PF13054.6 EKX46821.1 - 0.0084 16.1 0.0 0.012 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3915) DUF2122 PF09895.9 EKX46821.1 - 0.038 14.4 0.0 0.12 12.8 0.0 1.8 2 0 0 2 2 2 0 RecB-family nuclease (DUF2122) zf-RING_2 PF13639.6 EKX46822.1 - 2e-13 50.4 9.9 2.3e-13 50.3 9.9 1.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EKX46822.1 - 9.9e-13 47.6 5.1 9.9e-13 47.6 5.1 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 EKX46822.1 - 1.1e-08 34.8 7.8 1.4e-08 34.5 7.8 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EKX46822.1 - 1.1e-08 34.7 10.6 1.4e-08 34.4 10.6 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX46822.1 - 1.5e-06 28.1 4.3 1.5e-06 28.1 4.3 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 EKX46822.1 - 1.7e-06 28.2 12.0 4.9e-06 26.7 12.0 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EKX46822.1 - 1.8e-06 27.7 7.2 2.2e-06 27.4 7.2 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX46822.1 - 7.6e-06 25.8 7.0 9.1e-06 25.5 7.0 1.1 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EKX46822.1 - 7.2e-05 22.3 6.4 9.8e-05 21.9 6.4 1.2 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EKX46822.1 - 0.00022 21.0 8.6 0.00029 20.6 8.6 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EKX46822.1 - 0.00023 21.1 7.5 0.00033 20.7 7.5 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 EKX46822.1 - 0.045 13.9 9.2 0.41 10.8 9.2 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 EKX46822.1 - 0.051 13.7 8.5 0.18 11.9 8.3 1.8 1 1 0 1 1 1 0 RING-variant domain Methyltransf_32 PF13679.6 EKX46823.1 - 1.2e-12 48.2 6.3 4.7e-12 46.2 5.9 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX46823.1 - 1.1e-09 38.3 0.0 1.7e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 EKX46823.1 - 3.1e-07 29.9 0.0 4.7e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G TRM13 PF05206.14 EKX46823.1 - 1.4e-06 28.0 1.8 2.5e-06 27.2 1.6 1.5 1 1 0 1 1 1 1 Methyltransferase TRM13 PCMT PF01135.19 EKX46823.1 - 5.1e-06 26.4 0.0 7.9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 EKX46823.1 - 1.2e-05 26.0 0.1 2.9e-05 24.7 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EKX46823.1 - 0.0001 22.1 0.0 0.00017 21.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EKX46823.1 - 0.00053 19.6 0.0 0.00093 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EKX46823.1 - 0.0012 19.4 0.0 0.0033 18.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX46823.1 - 0.0084 16.0 0.0 0.017 14.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EKX46823.1 - 0.018 14.7 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Ubie_methyltran PF01209.18 EKX46823.1 - 0.053 12.8 0.0 1.8 7.9 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EKX46823.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase FUSC PF04632.12 EKX46823.1 - 0.77 8.2 2.0 0.94 7.9 2.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family WD40 PF00400.32 EKX46824.1 - 8.8e-15 54.9 1.5 5.2e-05 23.9 0.1 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX46824.1 - 0.00028 21.1 0.0 0.023 15.0 0.0 2.7 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EKX46824.1 - 0.003 17.5 0.0 0.0074 16.2 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EKX46824.1 - 0.0097 14.9 0.0 2.7 6.9 0.0 2.8 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EKX46824.1 - 0.041 13.8 1.4 5.6 7.0 0.0 2.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Glyco_transf_56 PF07429.11 EKX46826.1 - 0.035 13.2 0.1 0.043 12.9 0.1 1.1 1 0 0 1 1 1 0 4-alpha-L-fucosyltransferase glycosyl transferase group 56 BAR_3 PF16746.5 EKX46828.1 - 0.0058 16.4 11.3 0.01 15.6 11.3 1.3 1 1 0 1 1 1 1 BAR domain of APPL family BAR PF03114.18 EKX46828.1 - 0.019 14.6 15.1 0.041 13.5 15.0 1.8 1 1 0 1 1 1 0 BAR domain HSP9_HSP12 PF04119.12 EKX46828.1 - 0.042 14.2 0.4 0.18 12.2 0.1 2.2 2 0 0 2 2 2 0 Heat shock protein 9/12 Seryl_tRNA_N PF02403.22 EKX46828.1 - 1 9.6 10.2 0.73 10.1 4.1 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain NHL PF01436.21 EKX46829.1 - 0.0081 16.2 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 NHL repeat NHL PF01436.21 EKX46830.1 - 1.3e-13 50.2 5.2 0.0081 16.2 0.0 5.7 5 0 0 5 5 5 3 NHL repeat SGL PF08450.12 EKX46830.1 - 2e-10 40.7 0.9 0.021 14.4 0.0 4.7 2 2 2 4 4 4 3 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 EKX46830.1 - 6.1e-08 32.3 0.8 5e-05 22.7 0.1 3.2 2 1 0 2 2 2 2 Lactonase, 7-bladed beta-propeller Arylesterase PF01731.20 EKX46830.1 - 2.2e-06 27.7 0.1 5.5 7.3 0.0 4.3 4 0 0 4 4 4 3 Arylesterase Str_synth PF03088.16 EKX46830.1 - 9.1e-05 22.5 0.0 1.9 8.6 0.0 3.5 3 0 0 3 3 3 2 Strictosidine synthase WD40 PF00400.32 EKX46830.1 - 0.0035 18.1 2.7 5.6 8.0 0.0 4.8 5 0 0 5 5 5 1 WD domain, G-beta repeat PD40 PF07676.12 EKX46830.1 - 0.02 14.8 0.2 3.4 7.7 0.0 3.1 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DUF4871 PF16167.5 EKX46830.1 - 0.14 12.2 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4871) BNR PF02012.20 EKX46832.1 - 0.0036 17.1 1.0 7.3 7.0 0.1 3.4 2 0 0 2 2 2 2 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 EKX46832.1 - 0.011 14.6 0.1 0.27 10.0 0.0 2.1 2 0 0 2 2 2 0 Sortilin, neurotensin receptor 3, Ank_2 PF12796.7 EKX46833.1 - 2e-14 53.9 0.0 5.3e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX46833.1 - 7.1e-12 45.6 0.2 1.7e-08 34.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX46833.1 - 5.9e-11 41.6 0.1 0.00076 19.7 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EKX46833.1 - 2.4e-10 40.4 0.4 0.0005 20.4 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EKX46833.1 - 0.00014 22.1 0.9 0.0048 17.2 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) p6 PF17548.2 EKX46834.1 - 0.066 13.2 0.1 1 9.4 0.0 2.4 2 0 0 2 2 2 0 Histone-like Protein p6 DUF2034 PF10356.9 EKX46835.1 - 0.01 15.3 0.0 0.025 14.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2034) Tn7_Tnp_TnsA_C PF08721.11 EKX46835.1 - 0.05 14.2 0.0 0.097 13.3 0.0 1.4 1 0 0 1 1 1 0 TnsA endonuclease C terminal VIT1 PF01988.19 EKX46835.1 - 0.09 12.6 1.2 0.13 12.1 1.2 1.6 1 1 0 1 1 1 0 VIT family DUF4726 PF15855.5 EKX46835.1 - 0.12 12.6 0.2 0.24 11.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4726) Pro-rich PF15240.6 EKX46836.1 - 0.0024 18.2 29.6 0.0028 17.9 29.6 1.1 1 0 0 1 1 1 1 Proline-rich LEA_5 PF00477.17 EKX46836.1 - 0.038 14.4 10.8 0.67 10.4 2.7 2.1 1 1 1 2 2 2 0 Small hydrophilic plant seed protein Extensin_2 PF04554.13 EKX46836.1 - 1.1 9.4 11.6 12 6.0 6.3 2.3 1 1 1 2 2 2 0 Extensin-like region Ank_2 PF12796.7 EKX46838.1 - 5.1e-14 52.6 0.3 1.8e-06 28.5 0.1 3.3 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX46838.1 - 3.6e-13 49.7 0.6 2.8e-06 27.8 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX46838.1 - 1e-11 44.7 0.2 0.033 14.7 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EKX46838.1 - 2.9e-07 30.6 1.6 0.068 13.5 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX46838.1 - 1.3e-06 28.3 0.2 10 7.0 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 EKX46839.1 - 8e-26 90.5 0.0 2e-15 57.1 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX46839.1 - 2.4e-18 64.3 0.0 0.00059 20.1 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 EKX46839.1 - 5.9e-18 65.0 0.0 3.1e-12 46.8 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX46839.1 - 1.9e-17 63.1 0.0 1.8e-09 37.6 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX46839.1 - 5.4e-13 48.7 0.0 0.00031 21.1 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat zf-MYND PF01753.18 EKX46839.1 - 3e-10 40.0 11.8 3e-10 40.0 11.8 2.4 2 0 0 2 2 2 1 MYND finger DUF1360 PF07098.11 EKX46839.1 - 0.26 11.2 1.2 0.83 9.6 1.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) zf-C6H2 PF15801.5 EKX46839.1 - 0.39 11.0 19.8 0.24 11.7 11.7 2.5 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding CENP-B_dimeris PF09026.10 EKX46839.1 - 1.4 9.4 12.8 5.2 7.5 12.8 2.0 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DZR PF12773.7 EKX46839.1 - 5.8 7.0 13.0 0.96 9.5 0.1 3.1 2 1 0 2 2 2 0 Double zinc ribbon WGG PF10273.9 EKX46840.1 - 3e-13 50.2 0.6 6.9e-13 49.1 0.1 1.8 2 1 0 2 2 2 1 Pre-rRNA-processing protein TSR2 GST_C_5 PF16865.5 EKX46840.1 - 0.01 16.4 0.0 0.019 15.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RPAP3_C PF13877.6 EKX46840.1 - 0.087 13.4 0.0 0.82 10.3 0.0 2.1 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 DUF3721 PF12518.8 EKX46841.1 - 0.0072 16.2 0.9 0.021 14.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function LRR_6 PF13516.6 EKX46842.1 - 1.1e-35 118.6 24.7 1.1e-05 25.1 0.1 8.6 9 0 0 9 9 9 7 Leucine Rich repeat LRR_4 PF12799.7 EKX46842.1 - 1.7e-08 34.6 11.8 0.086 13.3 0.7 5.6 2 2 5 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX46842.1 - 1e-07 31.6 15.1 0.037 13.8 0.3 6.8 1 1 5 6 6 6 6 Leucine rich repeat LRR_1 PF00560.33 EKX46842.1 - 2.3e-07 30.4 0.7 4.9 8.1 0.0 6.9 8 1 0 8 8 8 2 Leucine Rich Repeat PH PF00169.29 EKX46844.1 - 2.5e-08 34.4 0.7 5.4e-08 33.3 0.7 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EKX46844.1 - 0.00025 21.3 0.2 0.00061 20.0 0.2 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 EKX46844.1 - 0.028 14.8 2.8 0.028 14.8 2.8 2.4 2 2 0 2 2 2 0 Pleckstrin homology domain Ank_2 PF12796.7 EKX46845.1 - 2.4e-11 44.1 0.3 3.7e-11 43.5 0.3 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX46845.1 - 3.1e-08 34.0 1.0 7.1e-07 29.7 0.2 2.7 2 1 1 3 3 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX46845.1 - 1.5e-05 25.2 0.4 6.5e-05 23.2 0.2 2.1 2 0 0 2 2 1 1 Ankyrin repeat Ank_5 PF13857.6 EKX46845.1 - 0.00012 22.2 0.1 0.0012 19.1 0.0 2.5 3 0 0 3 3 2 1 Ankyrin repeats (many copies) Trypan_PARP PF05887.11 EKX46845.1 - 0.0019 18.2 8.7 0.003 17.5 8.7 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DDHD PF02862.17 EKX46845.1 - 0.0032 17.7 1.2 0.0034 17.6 1.2 1.2 1 0 0 1 1 1 1 DDHD domain Ank_3 PF13606.6 EKX46845.1 - 0.0053 17.1 0.3 0.027 15.0 0.1 2.3 3 0 0 3 3 1 1 Ankyrin repeat PTPRCAP PF15713.5 EKX46845.1 - 0.0054 17.0 17.2 0.0054 17.0 17.2 2.0 2 0 0 2 2 2 1 Protein tyrosine phosphatase receptor type C-associated cwf18 PF08315.12 EKX46845.1 - 0.013 16.1 11.6 0.013 16.1 11.6 1.6 2 0 0 2 2 1 0 cwf18 pre-mRNA splicing factor TERB2 PF15101.6 EKX46845.1 - 0.023 14.8 7.6 0.034 14.2 7.6 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 CDC45 PF02724.14 EKX46845.1 - 0.037 12.3 16.1 0.05 11.9 16.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 EKX46845.1 - 0.086 13.3 6.9 0.15 12.5 6.9 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Suf PF05843.14 EKX46845.1 - 0.3 11.0 8.4 0.42 10.5 8.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RP-C_C PF11800.8 EKX46845.1 - 0.32 11.0 8.4 0.47 10.5 8.4 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Auts2 PF15336.6 EKX46845.1 - 0.35 11.0 5.7 0.59 10.2 5.7 1.3 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein RR_TM4-6 PF06459.12 EKX46845.1 - 0.38 10.5 15.2 0.59 9.9 15.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2828 PF11443.8 EKX46845.1 - 0.52 8.3 9.1 0.72 7.9 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Plasmodium_Vir PF05795.11 EKX46845.1 - 0.54 9.6 6.8 0.71 9.2 6.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TFIIF_alpha PF05793.12 EKX46845.1 - 0.54 8.8 23.3 0.77 8.3 23.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Lin-8 PF03353.15 EKX46845.1 - 0.58 9.7 14.6 0.8 9.2 14.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Zip PF02535.22 EKX46845.1 - 0.64 9.2 3.8 0.66 9.1 3.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4746 PF15928.5 EKX46845.1 - 0.72 9.2 11.4 1.1 8.7 11.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) MDM10 PF12519.8 EKX46845.1 - 0.85 8.4 6.5 1.1 8.1 6.5 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF5523 PF17661.1 EKX46845.1 - 0.91 9.2 19.9 0.98 9.1 17.9 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5523) Rxt3 PF08642.10 EKX46845.1 - 0.95 10.2 5.9 1.6 9.5 5.9 1.4 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Presenilin PF01080.17 EKX46845.1 - 0.99 8.1 14.9 1.3 7.7 14.9 1.1 1 0 0 1 1 1 0 Presenilin Rrn6 PF10214.9 EKX46845.1 - 1.2 7.5 11.0 1.5 7.2 11.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Atrophin-1 PF03154.15 EKX46845.1 - 1.3 7.3 18.2 1.7 6.9 18.2 1.1 1 0 0 1 1 1 0 Atrophin-1 family Bud13 PF09736.9 EKX46845.1 - 1.3 9.4 18.7 1.1 9.6 16.2 1.9 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex DUF1980 PF09323.10 EKX46845.1 - 1.7 8.6 3.5 2.5 8.0 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) RAG1_imp_bd PF12560.8 EKX46845.1 - 1.8 8.1 9.7 2 7.9 7.3 1.8 2 0 0 2 2 2 0 RAG1 importin binding Merozoite_SPAM PF07133.11 EKX46845.1 - 2.1 8.3 27.0 3.9 7.4 27.0 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Tim54 PF11711.8 EKX46845.1 - 2.1 7.1 12.3 2.7 6.7 12.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CPSF100_C PF13299.6 EKX46845.1 - 2.3 8.4 11.5 4.1 7.5 11.5 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Dynactin_p62 PF05502.13 EKX46845.1 - 3.2 6.4 10.3 4.2 6.0 10.3 1.1 1 0 0 1 1 1 0 Dynactin p62 family NPR3 PF03666.13 EKX46845.1 - 3.4 6.3 11.8 4.4 6.0 11.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM176 PF14851.6 EKX46845.1 - 3.8 7.2 13.7 7.9 6.1 13.7 1.6 1 0 0 1 1 1 0 FAM176 family SLC12 PF03522.15 EKX46845.1 - 4.1 6.3 12.0 5.5 5.9 12.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Folliculin PF11704.8 EKX46845.1 - 4.3 7.2 7.1 8.5 6.2 7.1 1.6 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF2722 PF10846.8 EKX46845.1 - 4.5 6.1 18.0 6.1 5.7 18.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Paf1 PF03985.13 EKX46845.1 - 4.6 6.1 25.9 6.8 5.6 25.9 1.2 1 0 0 1 1 1 0 Paf1 DUF4175 PF13779.6 EKX46845.1 - 5.5 4.8 23.9 7.2 4.4 23.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) G0-G1_switch_2 PF15103.6 EKX46845.1 - 6.8 7.2 9.7 13 6.3 9.7 1.5 1 0 0 1 1 1 0 G0/G1 switch protein 2 NOA36 PF06524.12 EKX46845.1 - 6.8 5.9 12.7 12 5.2 12.7 1.3 1 0 0 1 1 1 0 NOA36 protein Peroxin-13_N PF04088.13 EKX46845.1 - 6.8 7.0 5.1 12 6.1 5.1 1.4 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DUF4554 PF15091.6 EKX46845.1 - 6.9 5.5 7.3 9.2 5.0 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) CobT PF06213.12 EKX46845.1 - 6.9 6.0 27.1 11 5.4 27.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RPN2_C PF18004.1 EKX46845.1 - 7.8 6.4 15.5 13 5.7 15.5 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Spt20 PF12090.8 EKX46845.1 - 8 6.0 23.7 14 5.2 23.7 1.4 1 0 0 1 1 1 0 Spt20 family TFB6 PF17110.5 EKX46845.1 - 8 6.2 10.7 14 5.4 10.7 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DDRGK PF09756.9 EKX46845.1 - 8.4 5.9 24.6 13 5.3 24.6 1.2 1 0 0 1 1 1 0 DDRGK domain DUF913 PF06025.12 EKX46845.1 - 9.5 5.1 9.0 13 4.6 9.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) PDZ PF00595.24 EKX46846.1 - 4.3e-09 36.6 0.4 8.2e-09 35.7 0.4 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX46846.1 - 6.2e-09 36.1 0.0 2e-08 34.4 0.0 1.9 1 1 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX46846.1 - 2e-06 27.6 0.0 0.0019 18.0 0.0 2.6 2 0 0 2 2 2 2 PDZ domain Spc24 PF08286.11 EKX46846.1 - 0.065 13.5 3.7 0.18 12.0 3.7 1.8 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Phage_P2_GpE PF06528.12 EKX46846.1 - 0.072 12.7 0.3 0.19 11.3 0.3 1.7 1 0 0 1 1 1 0 Phage P2 GpE PDZ_4 PF17816.1 EKX46846.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 PDZ domain Histidinol_dh PF00815.20 EKX46846.1 - 0.3 10.0 1.1 0.47 9.4 1.1 1.2 1 0 0 1 1 1 0 Histidinol dehydrogenase Methyltransf_23 PF13489.6 EKX46847.1 - 8.3e-10 38.7 0.0 4.7e-09 36.3 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain NAD_binding_8 PF13450.6 EKX46847.1 - 4.5e-07 30.0 0.0 1.3e-06 28.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Methyltransf_11 PF08241.12 EKX46847.1 - 1.1e-06 29.2 0.0 5.7e-06 26.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Amino_oxidase PF01593.24 EKX46847.1 - 1.2e-05 24.9 0.1 0.084 12.1 0.0 2.8 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase Methyltransf_25 PF13649.6 EKX46847.1 - 0.00015 22.4 0.0 0.00082 20.0 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EKX46847.1 - 0.022 14.0 0.3 0.11 11.7 0.3 1.9 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF1980 PF09323.10 EKX46848.1 - 0.048 13.6 0.0 0.11 12.4 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) TORC_M PF12885.7 EKX46848.1 - 0.17 11.8 0.6 0.29 11.1 0.6 1.3 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain DUF1840 PF08895.11 EKX46848.1 - 0.21 11.9 4.3 0.45 10.9 4.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Peptidase_S49_N PF08496.10 EKX46848.1 - 2.5 8.1 6.1 5.2 7.1 6.1 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RR_TM4-6 PF06459.12 EKX46848.1 - 2.9 7.6 9.5 4.3 7.1 9.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CPSF100_C PF13299.6 EKX46848.1 - 4 7.6 8.7 6.3 7.0 8.7 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal VIR_N PF15912.5 EKX46848.1 - 5.8 6.4 9.2 9.6 5.7 9.2 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal TRAP_alpha PF03896.16 EKX46848.1 - 6.1 6.0 6.9 11 5.1 6.9 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DivIC PF04977.15 EKX46849.1 - 0.41 10.5 4.6 0.83 9.5 4.6 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF996 PF06195.13 EKX46850.1 - 0.032 14.5 4.8 0.099 12.9 4.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF996) Cytochrom_B_N_2 PF13631.6 EKX46850.1 - 0.036 14.1 1.6 0.24 11.4 1.1 2.0 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB DUF4131 PF13567.6 EKX46850.1 - 5.5 6.6 12.6 8.1 6.1 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) ubiquitin PF00240.23 EKX46851.1 - 3.2e-21 74.8 2.6 9.6e-12 44.5 0.2 3.5 2 1 1 3 3 3 2 Ubiquitin family Ubiquitin_2 PF14560.6 EKX46851.1 - 9.5e-07 29.2 0.6 0.068 13.6 0.1 2.8 2 1 0 2 2 2 2 Ubiquitin-like domain Rad60-SLD PF11976.8 EKX46851.1 - 3.2e-06 26.9 0.0 0.00018 21.2 0.1 2.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EKX46851.1 - 7.6e-06 26.2 0.3 0.0032 17.8 0.1 2.9 2 2 0 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 EKX46851.1 - 0.0032 17.3 0.0 2.7 8.0 0.0 2.5 2 1 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 EKX46851.1 - 0.014 16.0 0.6 0.3 11.7 0.0 2.5 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain FlgT_C PF16538.5 EKX46851.1 - 0.14 12.7 0.1 0.91 10.1 0.0 2.4 3 0 0 3 3 3 0 Flagellar assembly protein T, C-terminal domain PAP_central PF04928.17 EKX46852.1 - 5e-73 245.1 0.0 6.7e-73 244.7 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EKX46852.1 - 2e-09 37.3 0.1 3.5e-06 26.8 0.0 2.8 3 0 0 3 3 3 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EKX46852.1 - 2.3e-06 27.8 0.0 5.1e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF4269 PF14091.6 EKX46852.1 - 0.017 15.4 0.1 0.088 13.0 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4269) Vps36-NZF-N PF16988.5 EKX46852.1 - 0.023 14.1 1.8 0.064 12.7 1.8 1.8 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Polbeta PF18765.1 EKX46852.1 - 0.033 14.3 0.0 0.085 12.9 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase zf-Sec23_Sec24 PF04810.15 EKX46852.1 - 0.12 12.5 0.6 0.27 11.3 0.6 1.5 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger PAP_central PF04928.17 EKX46853.1 - 3.8e-72 242.2 0.0 5.2e-72 241.8 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EKX46853.1 - 7.4e-12 45.2 0.0 3.1e-06 26.9 0.0 2.6 2 0 0 2 2 2 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EKX46853.1 - 3.7e-06 27.1 0.0 9.5e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF4269 PF14091.6 EKX46853.1 - 0.017 15.4 0.1 0.12 12.6 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4269) Vps36-NZF-N PF16988.5 EKX46853.1 - 0.023 14.1 1.7 0.057 12.8 1.7 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Polbeta PF18765.1 EKX46853.1 - 0.041 14.0 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase zf-Sec23_Sec24 PF04810.15 EKX46853.1 - 0.12 12.5 0.6 0.25 11.4 0.6 1.5 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger MetOD2 PF18548.1 EKX46853.1 - 0.13 12.4 0.2 20 5.4 0.0 2.6 2 0 0 2 2 2 0 Metanogen output domain 2 tRNA_NucTransf2 PF09249.11 EKX46853.1 - 0.19 12.0 0.3 6.2 7.1 0.1 2.6 3 0 0 3 3 3 0 tRNA nucleotidyltransferase, second domain Ribosomal_L13 PF00572.18 EKX46854.1 - 2.2e-08 34.4 0.0 2.6e-06 27.7 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 RAP PF08373.10 EKX46855.1 - 8.4e-19 67.4 0.0 1e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 RAP domain MTES_1575 PF18741.1 EKX46855.1 - 0.16 12.2 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 REase_MTES_1575 Ank_4 PF13637.6 EKX46856.1 - 2.8e-27 94.7 0.9 1.5e-08 35.0 0.0 5.6 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX46856.1 - 5.5e-26 91.0 2.6 1.2e-10 41.8 0.3 4.4 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EKX46856.1 - 2e-21 75.4 7.5 0.00024 21.4 0.0 6.5 5 1 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 EKX46856.1 - 2e-18 66.2 4.9 1.6e-05 25.1 0.0 5.6 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX46856.1 - 5.6e-18 63.2 6.6 0.0012 19.1 0.0 6.7 5 1 1 6 6 6 5 Ankyrin repeat SOG2 PF10428.9 EKX46856.1 - 0.0057 15.9 13.2 0.0078 15.5 13.2 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein CDC37_N PF03234.14 EKX46856.1 - 0.033 15.1 2.7 0.033 15.1 2.7 2.0 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Ndc1_Nup PF09531.10 EKX46856.1 - 0.18 10.5 7.3 0.24 10.1 7.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pox_Ag35 PF03286.14 EKX46858.1 - 0.0072 16.1 7.2 0.0072 16.1 7.2 1.1 1 0 0 1 1 1 1 Pox virus Ag35 surface protein FAM176 PF14851.6 EKX46858.1 - 0.0085 15.8 8.0 0.012 15.3 8.0 1.3 1 0 0 1 1 1 1 FAM176 family Sigma70_ner PF04546.13 EKX46858.1 - 0.067 13.1 11.5 0.062 13.2 11.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region TRAP_alpha PF03896.16 EKX46858.1 - 0.14 11.4 7.2 0.14 11.3 7.2 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2796 PF10986.8 EKX46858.1 - 0.15 12.1 5.9 0.17 11.9 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) RXT2_N PF08595.11 EKX46858.1 - 0.17 11.9 9.6 0.18 11.8 9.6 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal D123 PF07065.14 EKX46858.1 - 0.24 10.5 3.5 0.25 10.5 3.5 1.1 1 0 0 1 1 1 0 D123 NOA36 PF06524.12 EKX46858.1 - 0.24 10.7 23.2 0.26 10.6 23.2 1.0 1 0 0 1 1 1 0 NOA36 protein Dicty_REP PF05086.12 EKX46858.1 - 0.27 9.2 14.7 0.28 9.1 14.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF913 PF06025.12 EKX46858.1 - 0.54 9.2 2.8 0.49 9.3 2.8 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Radial_spoke PF04712.12 EKX46858.1 - 0.65 8.9 9.2 0.88 8.4 9.2 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein CobT PF06213.12 EKX46858.1 - 0.83 9.0 15.4 0.83 9.0 15.4 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 EKX46858.1 - 0.84 7.9 16.0 0.85 7.8 16.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EKX46858.1 - 0.89 7.7 18.4 0.88 7.7 18.4 1.0 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 EKX46858.1 - 1.5 8.3 18.9 1.7 8.2 18.9 1.0 1 0 0 1 1 1 0 PPP4R2 ANAPC15 PF15243.6 EKX46858.1 - 1.7 9.1 21.1 2.4 8.6 21.1 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 CENP-B_dimeris PF09026.10 EKX46858.1 - 2 8.8 28.0 3.1 8.3 28.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cytomega_UL84 PF06284.11 EKX46858.1 - 2.6 6.4 9.7 2.9 6.3 9.7 1.0 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein RNA_pol_3_Rpc31 PF11705.8 EKX46858.1 - 3.5 7.8 23.6 3.8 7.7 23.6 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TFB6 PF17110.5 EKX46858.1 - 5.4 6.7 11.6 5.7 6.6 11.6 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH PBP1_TM PF14812.6 EKX46858.1 - 6 7.3 17.7 9.7 6.6 17.7 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4820 PF16091.5 EKX46858.1 - 7.2 5.9 6.6 7.4 5.9 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DNA_pol_phi PF04931.13 EKX46858.1 - 8.3 4.4 27.9 8.8 4.3 27.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 EKX46858.1 - 8.5 5.7 20.4 8.4 5.7 20.4 1.0 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 EKX46858.1 - 9.1 5.9 20.9 11 5.6 20.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ank_4 PF13637.6 EKX46859.1 - 8.4e-11 42.2 0.0 9.4e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX46859.1 - 2.6e-10 40.8 0.1 2.7e-10 40.7 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX46859.1 - 1e-08 35.2 0.0 1.2e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX46859.1 - 7.2e-08 32.6 0.1 2.6e-06 27.6 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EKX46859.1 - 1.1e-07 31.5 0.0 1.1e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat ParcG PF10274.9 EKX46860.1 - 1.9e-83 279.1 0.0 2.1e-83 278.9 0.0 1.0 1 0 0 1 1 1 1 Parkin co-regulated protein DCB PF16213.5 EKX46860.1 - 0.048 13.3 0.0 0.062 13.0 0.0 1.1 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 COG2 PF06148.11 EKX46861.1 - 2.6e-22 79.4 0.1 2.6e-22 79.4 0.1 3.1 4 0 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 EKX46861.1 - 1.2e-16 61.2 0.1 6.5e-16 58.9 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) Vps51 PF08700.11 EKX46861.1 - 0.071 13.2 0.2 0.66 10.1 0.0 2.8 4 0 0 4 4 4 0 Vps51/Vps67 WRNPLPNID PF15017.6 EKX46861.1 - 6.1 7.8 8.8 2.9 8.8 0.1 3.6 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box COG2 PF06148.11 EKX46862.1 - 2.6e-22 79.3 0.1 2.6e-22 79.3 0.1 3.5 4 0 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 EKX46862.1 - 1.4e-13 51.3 0.4 8e-13 48.9 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) Cytomega_UL84 PF06284.11 EKX46862.1 - 0.0043 15.6 0.8 0.0097 14.4 0.8 1.5 1 0 0 1 1 1 1 Cytomegalovirus UL84 protein RLL PF10036.9 EKX46862.1 - 0.039 13.8 1.1 0.3 10.9 2.5 1.7 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein Vps51 PF08700.11 EKX46862.1 - 0.15 12.2 1.8 0.67 10.1 0.0 3.1 5 0 0 5 5 5 0 Vps51/Vps67 WRNPLPNID PF15017.6 EKX46862.1 - 1.9 9.4 11.2 2.9 8.8 0.1 3.7 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box Baculo_PEP_C PF04513.12 EKX46862.1 - 5.4 7.0 5.6 39 4.3 0.2 3.6 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1676 PF07898.13 EKX46863.1 - 0.08 13.0 0.3 0.13 12.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Thermopsin PF05317.11 EKX46863.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Thermopsin DUF4191 PF13829.6 EKX46863.1 - 2.4 7.4 6.4 3.9 6.7 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) SH3_2 PF07653.17 EKX46864.1 - 1.2e-14 53.7 0.0 2.1e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EKX46864.1 - 2.3e-14 53.0 0.2 4e-14 52.2 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EKX46864.1 - 4.3e-14 51.8 0.4 7.6e-14 51.0 0.4 1.4 1 0 0 1 1 1 1 SH3 domain BAR PF03114.18 EKX46864.1 - 5.6e-10 39.3 15.6 1.2e-06 28.4 7.7 2.3 1 1 0 2 2 2 2 BAR domain BAR_3 PF16746.5 EKX46864.1 - 0.0036 17.1 11.7 0.0071 16.1 3.1 3.0 1 1 2 3 3 3 2 BAR domain of APPL family US30 PF17624.2 EKX46864.1 - 0.069 12.2 0.1 0.3 10.1 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function Thr_synth_N PF14821.6 EKX46865.1 - 8.6e-26 90.0 0.2 3e-25 88.2 0.0 2.1 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 EKX46865.1 - 2.3e-18 66.7 0.0 1.8e-17 63.7 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Nop10p PF04135.12 EKX46865.1 - 0.87 9.7 2.8 11 6.2 0.3 3.3 3 1 0 3 3 3 0 Nucleolar RNA-binding protein, Nop10p family DUF4682 PF15733.5 EKX46866.1 - 0.044 14.4 0.0 0.054 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4682) TLD PF07534.16 EKX46867.1 - 1.3e-08 35.2 0.0 2.2e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 TLD HEPN_AbiV PF18728.1 EKX46867.1 - 0.083 13.0 0.3 0.13 12.4 0.3 1.2 1 0 0 1 1 1 0 AbiV DUF4350 PF14258.6 EKX46867.1 - 0.11 13.0 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) MIT PF04212.18 EKX46867.1 - 0.15 12.1 0.6 0.26 11.4 0.6 1.3 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain LysM PF01476.20 EKX46868.1 - 1.9e-07 31.0 0.0 0.00071 19.6 0.0 2.6 2 0 0 2 2 2 2 LysM domain Rieske PF00355.26 EKX46870.1 - 4e-16 58.7 0.1 6.4e-16 58.1 0.1 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 EKX46870.1 - 8e-11 41.8 0.0 1.1e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Ank_2 PF12796.7 EKX46871.1 - 2.3e-16 60.1 0.0 7.1e-16 58.6 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX46871.1 - 4.1e-15 55.5 0.2 9.7e-06 25.8 0.2 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EKX46871.1 - 1.5e-14 52.6 0.0 1.6e-05 24.9 0.1 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EKX46871.1 - 6.4e-14 52.1 0.6 6.8e-09 36.1 0.1 2.6 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX46871.1 - 5.3e-07 29.8 2.0 0.00015 22.0 0.3 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ferrochelatase PF00762.19 EKX46871.1 - 0.029 13.5 0.0 0.03 13.4 0.0 1.1 1 0 0 1 1 1 0 Ferrochelatase SQS_PSY PF00494.19 EKX46872.1 - 2.4e-66 223.9 0.1 2.8e-66 223.7 0.1 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase MazE_antitoxin PF04014.18 EKX46872.1 - 0.01 15.8 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 Antidote-toxin recognition MazE, bacterial antitoxin HEAT PF02985.22 EKX46873.1 - 2.5e-09 36.6 0.0 0.0027 17.8 0.0 4.8 6 0 0 6 6 6 2 HEAT repeat Arm PF00514.23 EKX46873.1 - 1.7e-08 34.2 0.0 0.0022 18.0 0.0 3.4 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EKX46873.1 - 7.3e-07 29.5 0.0 0.001 19.4 0.0 3.6 2 2 1 3 3 3 1 HEAT repeats V-ATPase_H_N PF03224.14 EKX46873.1 - 0.0016 17.8 0.2 0.017 14.5 0.0 1.9 1 1 1 2 2 2 2 V-ATPase subunit H HEAT_EZ PF13513.6 EKX46873.1 - 0.0017 18.8 0.2 0.19 12.3 0.0 4.0 3 2 3 6 6 6 2 HEAT-like repeat HEAT_PBS PF03130.16 EKX46873.1 - 0.08 13.7 2.1 1.8 9.5 0.5 3.5 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat HP0268 PF18618.1 EKX46873.1 - 0.11 12.9 1.7 0.28 11.6 0.5 2.2 2 0 0 2 2 2 0 HP0268 Sec1 PF00995.23 EKX46874.1 - 3.2e-120 403.1 1.5 3.8e-120 402.8 1.5 1.0 1 0 0 1 1 1 1 Sec1 family Acetyltransf_1 PF00583.25 EKX46875.1 - 3.9e-08 33.5 0.0 5.9e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EKX46875.1 - 0.00028 21.2 0.0 0.00047 20.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EKX46875.1 - 0.0026 17.7 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EKX46875.1 - 0.021 14.8 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_8 PF13523.6 EKX46875.1 - 0.12 12.0 0.3 0.33 10.6 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MIR PF02815.19 EKX46876.1 - 3.2e-18 66.3 2.8 4.3e-12 46.3 0.1 2.9 1 1 2 3 3 3 3 MIR domain Ins145_P3_rec PF08709.11 EKX46876.1 - 0.0013 18.0 0.2 0.0034 16.6 0.1 1.7 1 1 1 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor ZYG-11_interact PF05884.12 EKX46877.1 - 0.27 10.6 0.1 0.38 10.1 0.1 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF2722 PF10846.8 EKX46877.1 - 3.8 6.3 5.9 6 5.7 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) NOA36 PF06524.12 EKX46877.1 - 5 6.3 18.5 8.4 5.6 18.5 1.3 1 0 0 1 1 1 0 NOA36 protein DUF4611 PF15387.6 EKX46877.1 - 7.6 6.8 16.5 20 5.5 13.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.10 EKX46877.1 - 7.9 6.9 20.5 17 5.9 20.5 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 EKX46877.1 - 9.6 6.7 18.1 0.85 10.0 12.4 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HA2 PF04408.23 EKX46878.1 - 7e-21 74.5 0.0 1.4e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EKX46878.1 - 7.5e-17 61.5 0.0 1.5e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EKX46878.1 - 6.8e-12 45.7 0.0 1.9e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EKX46878.1 - 9.2e-08 32.0 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EKX46878.1 - 4.1e-06 27.1 0.0 1e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EKX46878.1 - 0.0004 20.2 0.0 0.00077 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EKX46878.1 - 0.00095 19.5 0.0 0.0019 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EKX46878.1 - 0.044 12.8 0.0 0.08 12.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Helicase_RecD PF05127.14 EKX46878.1 - 0.071 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Helicase AAA_7 PF12775.7 EKX46878.1 - 0.082 12.4 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Flavi_DEAD PF07652.14 EKX46878.1 - 0.16 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain SET PF00856.28 EKX46879.1 - 3e-10 40.7 0.0 1.1e-09 39.0 0.0 2.0 1 1 0 1 1 1 1 SET domain C2 PF00168.30 EKX46879.1 - 1.9e-07 31.3 0.1 5.6e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 C2 domain PDZ_6 PF17820.1 EKX46879.1 - 1.9e-05 24.4 0.0 4.7e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 PDZ domain BTAD PF03704.17 EKX46879.1 - 0.012 16.1 3.4 0.027 14.9 1.2 2.2 1 1 1 2 2 2 0 Bacterial transcriptional activator domain MOZART1 PF12554.8 EKX46880.1 - 1.7e-24 85.3 0.3 2.1e-24 85.0 0.3 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Glyco_transf_41 PF13844.6 EKX46881.1 - 2.1e-66 224.3 0.3 3.4e-34 118.1 0.0 3.6 1 1 0 2 2 2 2 Glycosyl transferase family 41 TPR_2 PF07719.17 EKX46881.1 - 7.9e-24 81.8 10.0 0.0001 22.1 0.0 9.2 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 EKX46881.1 - 2.2e-18 66.6 17.4 0.0002 22.0 4.5 6.3 5 2 2 7 7 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 EKX46881.1 - 9.2e-18 62.9 6.1 0.057 13.6 0.1 7.5 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 EKX46881.1 - 5.9e-17 60.7 11.6 0.00083 19.1 0.0 8.3 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 EKX46881.1 - 3.2e-16 59.4 23.7 1.5e-07 31.6 0.4 6.2 3 1 4 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 EKX46881.1 - 1.6e-14 53.2 21.1 0.00085 19.1 0.2 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX46881.1 - 2.9e-12 46.3 23.5 0.011 16.5 0.2 9.7 6 2 4 10 10 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 EKX46881.1 - 8.8e-12 44.5 5.5 0.00014 21.4 0.0 6.6 7 2 1 8 8 8 3 TPR repeat TPR_7 PF13176.6 EKX46881.1 - 4.1e-11 42.1 9.4 0.19 11.8 0.1 7.1 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 EKX46881.1 - 1.8e-10 40.5 1.0 1.7 9.2 0.1 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX46881.1 - 4.9e-09 36.6 13.0 0.00029 21.3 0.6 5.0 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX46881.1 - 3.3e-06 27.4 3.9 0.44 11.3 0.1 5.6 6 0 0 6 6 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX46881.1 - 3.5e-05 23.9 0.1 0.13 12.5 0.1 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 EKX46881.1 - 0.11 13.2 21.1 0.19 12.4 0.1 7.1 9 0 0 9 9 6 0 Tetratricopeptide repeat ChAPs PF09295.10 EKX46881.1 - 0.18 10.8 0.0 0.44 9.5 0.0 1.6 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) BCS1_N PF08740.11 EKX46882.1 - 7.9e-30 104.2 0.6 1.1e-29 103.8 0.6 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EKX46882.1 - 1.2e-21 77.5 0.0 2.5e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX46882.1 - 1.5e-05 25.4 0.1 4e-05 24.1 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EKX46882.1 - 0.00072 19.7 0.0 0.0013 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EKX46882.1 - 0.00096 19.2 0.0 0.0025 17.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 EKX46882.1 - 0.0021 17.9 0.0 0.0038 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EKX46882.1 - 0.004 16.4 0.0 0.0081 15.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 EKX46882.1 - 0.0059 16.9 0.1 0.043 14.1 0.0 2.2 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 EKX46882.1 - 0.0061 16.3 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EKX46882.1 - 0.0086 16.4 0.0 0.066 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EKX46882.1 - 0.03 14.1 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EKX46882.1 - 0.043 13.4 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EKX46882.1 - 0.063 13.8 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EKX46882.1 - 0.071 13.0 0.1 0.86 9.5 0.0 2.4 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 EKX46882.1 - 0.073 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 EKX46882.1 - 0.092 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.6 EKX46882.1 - 0.15 11.8 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 EKX46882.1 - 0.17 12.3 0.0 0.38 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_PrkA PF08298.11 EKX46882.1 - 0.2 10.5 0.0 0.42 9.5 0.0 1.4 2 0 0 2 2 2 0 PrkA AAA domain AAA_6 PF12774.7 EKX46882.1 - 0.21 10.5 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region TIP49 PF06068.13 EKX46882.1 - 0.24 10.6 0.0 0.38 9.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain DUF4116 PF13475.6 EKX46883.1 - 8.5e-100 326.4 0.3 1.9e-16 59.5 0.0 9.2 4 2 4 10 10 10 10 Domain of unknown function (DUF4116) XFP_C PF09363.10 EKX46883.1 - 0.031 13.8 0.2 38 3.7 0.0 3.9 3 1 1 4 4 4 0 XFP C-terminal domain GST_C PF00043.25 EKX46883.1 - 0.15 12.3 13.1 20 5.5 0.0 5.7 3 1 2 5 5 5 0 Glutathione S-transferase, C-terminal domain WW PF00397.26 EKX46884.1 - 3.7e-09 36.5 0.5 8e-09 35.4 0.5 1.6 1 0 0 1 1 1 1 WW domain HIRAN PF08797.11 EKX46885.1 - 3.5e-09 36.5 0.0 6.9e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Ank_2 PF12796.7 EKX46886.1 - 2.4e-17 63.3 0.1 2.7e-13 50.3 0.0 2.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX46886.1 - 4.9e-16 58.6 1.5 1.9e-06 28.1 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX46886.1 - 1.8e-14 53.9 1.9 1.5e-07 31.8 0.1 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EKX46886.1 - 4.8e-13 48.9 0.3 0.0046 17.4 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EKX46886.1 - 1.7e-11 43.3 0.3 0.043 14.4 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat COG5 PF10392.9 EKX46887.1 - 0.0043 17.2 3.8 0.025 14.7 1.8 2.2 1 1 0 2 2 2 1 Golgi transport complex subunit 5 Fib_alpha PF08702.10 EKX46887.1 - 0.0065 16.7 4.4 0.83 9.8 0.1 2.3 2 0 0 2 2 2 2 Fibrinogen alpha/beta chain family CdiI_2 PF18593.1 EKX46887.1 - 0.042 14.5 1.6 0.13 12.9 0.0 2.4 2 1 0 2 2 2 0 CdiI immunity protein DUF16 PF01519.16 EKX46887.1 - 0.059 13.9 6.1 0.25 11.8 1.4 2.4 2 1 0 2 2 2 0 Protein of unknown function DUF16 ApoLp-III PF07464.11 EKX46887.1 - 0.074 13.1 2.9 13 5.8 0.0 2.4 1 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Atg14 PF10186.9 EKX46887.1 - 0.21 10.7 10.4 0.29 10.2 10.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FAP206 PF12018.8 EKX46887.1 - 0.34 10.4 5.3 0.09 12.3 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function VGPC1_C PF16799.5 EKX46887.1 - 1.9 8.5 8.2 10 6.2 0.2 2.9 3 0 0 3 3 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 AAA_11 PF13086.6 EKX46887.1 - 3.4 7.4 8.5 4.6 6.9 8.5 1.3 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 EKX46887.1 - 8.9 5.8 14.9 20 4.6 14.9 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit Glyco_hydro_20 PF00728.22 EKX46889.1 - 7.5e-84 282.1 0.0 1.3e-77 261.6 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain CheR_N PF03705.15 EKX46889.1 - 0.1 12.3 0.3 0.22 11.3 0.0 1.6 2 0 0 2 2 2 0 CheR methyltransferase, all-alpha domain bcl-2I13 PF12201.8 EKX46889.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Bcl2-interacting killer, BH3-domain containing WD40 PF00400.32 EKX46891.1 - 2.9e-26 91.2 0.5 1.7e-09 38.1 0.2 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX46891.1 - 6.6e-26 90.4 0.6 6.8e-06 26.3 0.0 4.1 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EKX46891.1 - 6.3e-10 38.3 0.1 0.0038 15.9 0.0 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 IKI3 PF04762.12 EKX46891.1 - 3.4e-09 35.3 0.8 0.001 17.2 0.0 2.0 1 1 1 2 2 2 2 IKI3 family Ge1_WD40 PF16529.5 EKX46891.1 - 2.3e-08 33.4 0.1 0.026 13.5 0.0 3.4 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Ret2_MD PF18528.1 EKX46891.1 - 7.3e-05 23.1 0.1 2 8.9 0.0 3.5 2 1 2 4 4 4 2 RNA editing 3' terminal uridylyl transferase 2 middle domain PD40 PF07676.12 EKX46891.1 - 7.3e-05 22.6 0.0 7.5 6.6 0.0 4.3 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Defensin_RK-1 PF17860.1 EKX46891.1 - 0.00023 21.5 1.1 3.1 8.3 0.1 3.3 3 0 0 3 3 3 2 RK-1-like defensin Nbas_N PF15492.6 EKX46891.1 - 0.0026 17.1 0.2 4.6 6.5 0.0 3.3 1 1 3 4 4 4 1 Neuroblastoma-amplified sequence, N terminal DUF4144 PF13642.6 EKX46891.1 - 0.11 13.1 0.0 84 3.8 0.0 3.0 2 1 1 3 3 3 0 protein structure with unknown function DPPIV_N PF00930.21 EKX46891.1 - 0.22 10.3 0.2 35 3.0 0.0 3.1 2 2 2 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Ribonucleas_3_3 PF14622.6 EKX46892.1 - 7.8e-31 106.9 0.1 1.3e-30 106.2 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EKX46892.1 - 1.8e-17 63.9 0.1 5.3e-17 62.4 0.1 1.8 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 EKX46892.1 - 1.1e-07 32.4 0.0 2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif LSM PF01423.22 EKX46894.1 - 1e-15 57.2 0.1 1.4e-15 56.7 0.1 1.2 1 0 0 1 1 1 1 LSM domain HEAT_2 PF13646.6 EKX46896.1 - 1.8e-20 73.1 29.8 1.1e-07 32.2 0.2 8.2 5 1 2 8 8 8 5 HEAT repeats IU_nuc_hydro PF01156.19 EKX46896.1 - 2e-20 73.6 0.0 8.6e-20 71.5 0.0 2.1 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase HEAT PF02985.22 EKX46896.1 - 4.3e-20 70.1 25.3 0.11 12.9 0.1 11.9 12 0 0 12 12 10 5 HEAT repeat Adaptin_N PF01602.20 EKX46896.1 - 6.2e-11 41.5 0.1 6.7e-05 21.6 0.0 4.0 2 1 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 EKX46896.1 - 1.1e-09 38.5 13.4 0.0015 18.6 0.3 5.3 4 2 3 7 7 6 3 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 EKX46896.1 - 1.6e-06 28.3 0.0 0.4 10.9 0.0 5.3 2 2 2 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 EKX46896.1 - 0.00075 19.9 7.7 19 5.7 0.2 6.8 4 2 1 6 6 6 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Vac14_Fab1_bd PF12755.7 EKX46896.1 - 0.0014 19.1 0.5 5.5 7.6 0.0 5.0 3 2 2 5 5 5 1 Vacuolar 14 Fab1-binding region DUF5578 PF17741.1 EKX46896.1 - 0.0044 16.5 0.3 12 5.2 0.0 4.0 4 0 0 4 4 4 0 Family of unknown function (DUF5578) PBP1_TM PF14812.6 EKX46896.1 - 0.016 15.6 3.7 0.087 13.2 3.7 2.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal API5 PF05918.11 EKX46896.1 - 0.03 13.1 0.2 0.03 13.1 0.2 3.7 4 0 0 4 4 4 0 Apoptosis inhibitory protein 5 (API5) V-ATPase_H_N PF03224.14 EKX46896.1 - 0.062 12.6 0.0 4.3 6.5 0.0 3.2 2 1 1 3 3 3 0 V-ATPase subunit H DUF1509 PF07420.11 EKX46896.1 - 0.1 11.5 3.3 0.23 10.4 3.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) HEAT_EZ PF13513.6 EKX46896.1 - 1 9.9 26.3 8.8 7.0 0.0 9.2 8 2 2 10 10 10 0 HEAT-like repeat DUF4042 PF13251.6 EKX46896.1 - 1.3 8.7 6.8 4 7.1 0.2 4.8 3 2 2 6 6 6 0 Domain of unknown function (DUF4042) Arm PF00514.23 EKX46896.1 - 1.4 9.1 9.8 73 3.6 0.0 6.5 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 EKX46896.1 - 1.7 9.5 4.2 24 6.0 0.3 4.4 3 0 0 3 3 2 0 PBS lyase HEAT-like repeat E7 PF00527.18 EKX46896.1 - 1.9 8.7 5.1 1.8 8.8 1.9 2.6 2 0 0 2 2 2 0 E7 protein, Early protein GCIP PF13324.6 EKX46896.1 - 2.3 7.8 8.7 0.23 11.0 0.9 2.8 3 0 0 3 3 2 0 Grap2 and cyclin-D-interacting DivIC PF04977.15 EKX46896.1 - 3.3 7.6 6.0 3 7.7 0.8 3.1 2 1 0 2 2 2 0 Septum formation initiator CENP-B_dimeris PF09026.10 EKX46896.1 - 6.9 7.1 9.0 36 4.8 8.8 2.3 2 0 0 2 2 1 0 Centromere protein B dimerisation domain DUF4611 PF15387.6 EKX46896.1 - 8.5 6.7 13.2 0.091 13.0 2.9 3.3 3 0 0 3 3 2 0 Domain of unknown function (DUF4611) GTP_EFTU PF00009.27 EKX46897.1 - 3.1e-25 88.9 0.0 5.6e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EKX46897.1 - 6.4e-07 29.5 0.0 0.021 15.0 0.0 3.0 3 0 0 3 3 3 2 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 EKX46897.1 - 0.00025 21.4 0.1 0.00053 20.3 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EKX46897.1 - 0.003 17.6 0.0 0.026 14.6 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EKX46897.1 - 0.0048 16.7 0.0 0.0092 15.8 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 EKX46897.1 - 0.029 14.3 0.3 0.22 11.4 0.1 2.4 1 1 1 2 2 2 0 RsgA GTPase Melibiase PF02065.18 EKX46898.1 - 4.5e-142 473.1 0.0 5.7e-142 472.7 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 EKX46898.1 - 1.7e-61 208.0 0.0 3.1e-61 207.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 EKX46898.1 - 5.5e-13 49.2 0.0 5.7e-12 46.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 36 C-terminal domain Glyco_hydro_31 PF01055.26 EKX46898.1 - 4.3e-05 22.9 0.0 6.5e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Melibiase_2 PF16499.5 EKX46898.1 - 0.00018 20.8 0.0 0.00039 19.7 0.0 1.5 1 0 0 1 1 1 1 Alpha galactosidase A Raffinose_syn PF05691.12 EKX46898.1 - 0.16 9.7 0.0 0.24 9.1 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 NIF PF03031.18 EKX46899.1 - 1.6e-22 80.0 0.6 2.9e-22 79.1 0.6 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 EKX46899.1 - 3.7e-06 26.6 0.6 8.8e-06 25.4 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin family Pkinase PF00069.25 EKX46902.1 - 3e-61 207.1 0.0 3.3e-61 207.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX46902.1 - 1.7e-47 161.9 0.0 2.3e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX46902.1 - 4.2e-06 26.3 0.0 5.8e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EKX46902.1 - 5.6e-05 22.1 0.0 9.5e-05 21.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EKX46902.1 - 0.001 18.1 0.1 0.0012 17.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EKX46902.1 - 0.0014 18.0 0.7 0.0028 17.0 0.8 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EKX46902.1 - 0.052 13.1 0.2 0.074 12.6 0.2 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EKX46902.1 - 0.064 13.2 0.1 0.2 11.5 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family SARG PF15385.6 EKX46902.1 - 0.23 10.6 0.1 0.29 10.3 0.1 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein Rogdi_lz PF10259.9 EKX46904.1 - 8e-06 25.5 0.0 9.9e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein DHOR PF06537.11 EKX46905.1 - 0.035 12.7 0.0 0.053 12.1 0.0 1.2 1 0 0 1 1 1 0 Di-haem oxidoreductase, putative peroxidase NAP PF00956.18 EKX46907.1 - 7.9e-77 258.1 3.8 7.9e-77 258.1 3.8 3.1 3 2 0 3 3 3 1 Nucleosome assembly protein (NAP) Mst1_SARAH PF11629.8 EKX46907.1 - 0.0029 17.7 0.7 0.0029 17.7 0.7 2.0 2 0 0 2 2 2 1 C terminal SARAH domain of Mst1 PPP4R2 PF09184.11 EKX46907.1 - 0.2 11.2 28.4 1.3 8.5 10.3 2.5 2 0 0 2 2 2 0 PPP4R2 Nup_retrotrp_bd PF10599.9 EKX46907.1 - 3.4 8.4 7.5 6.6 7.5 7.5 1.4 1 0 0 1 1 1 0 Retro-transposon transporting motif RPA43_OB PF17875.1 EKX46907.1 - 4.1 8.0 11.5 7.1 7.3 0.5 3.3 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I eIF2A PF08662.11 EKX46908.1 - 3e-59 200.2 0.0 3.4e-59 200.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 EKX46908.1 - 0.021 15.1 0.0 2.7 8.3 0.0 3.2 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EKX46908.1 - 0.055 14.4 2.6 6.3 7.8 0.3 3.6 3 1 1 4 4 4 0 WD domain, G-beta repeat A_deaminase PF00962.22 EKX46909.1 - 2.7e-18 66.4 0.2 1.5e-17 64.0 0.2 1.9 1 1 0 1 1 1 1 Adenosine/AMP deaminase Paired_CXXCH_1 PF09699.10 EKX46909.1 - 0.019 14.7 1.5 1.4 8.7 0.1 2.6 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) Amidohydro_1 PF01979.20 EKX46909.1 - 0.032 13.5 0.0 0.039 13.3 0.0 1.4 1 1 0 1 1 1 0 Amidohydrolase family TIR_2 PF13676.6 EKX46910.1 - 0.00022 21.8 0.0 0.0015 19.1 0.0 2.1 1 1 1 2 2 2 1 TIR domain YmdB PF13277.6 EKX46911.1 - 0.016 14.6 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 YmdB-like protein PDZ_6 PF17820.1 EKX46913.1 - 5.6e-20 70.9 7.8 1.9e-10 40.4 0.7 4.2 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 EKX46913.1 - 4.1e-11 43.1 0.1 0.00016 22.0 0.0 3.9 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 EKX46913.1 - 3.2e-07 30.6 0.1 0.12 12.7 0.0 4.0 4 1 0 4 4 4 3 PDZ domain BRAP2 PF07576.12 EKX46914.1 - 7.8e-27 93.4 0.2 1.5e-26 92.5 0.2 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 EKX46914.1 - 9.8e-19 67.5 6.9 2.9e-18 65.9 6.9 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-rbx1 PF12678.7 EKX46914.1 - 1.1e-05 25.7 3.5 4.2e-05 23.7 3.5 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EKX46914.1 - 1.4e-05 25.3 7.3 1.4e-05 25.3 7.3 2.7 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX46914.1 - 0.00053 19.8 6.3 0.00053 19.8 6.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EKX46914.1 - 0.0022 17.7 2.3 0.0085 15.8 2.3 2.1 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 EKX46914.1 - 0.0083 16.1 4.8 0.0083 16.1 4.8 2.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EKX46914.1 - 0.017 15.0 8.3 0.058 13.3 8.3 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) EST1 PF10374.9 EKX46914.1 - 0.24 12.0 5.2 0.34 11.5 4.6 1.6 1 1 0 1 1 1 0 Telomerase activating protein Est1 GvpL_GvpF PF06386.11 EKX46914.1 - 2.1 8.2 10.8 4.2 7.2 10.8 1.5 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF UPF0242 PF06785.11 EKX46914.1 - 2.8 8.0 19.5 5.3 7.1 19.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Guanylate_cyc PF00211.20 EKX46915.1 - 9.6e-14 51.4 0.0 1.7e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain TMEM107 PF14995.6 EKX46916.1 - 3.3e-29 101.8 18.6 3.9e-29 101.6 18.6 1.0 1 0 0 1 1 1 1 Transmembrane protein MFS_1 PF07690.16 EKX46917.1 - 2.5e-33 115.5 11.2 1.7e-25 89.7 9.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EKX46917.1 - 1.7e-11 43.7 8.1 8e-09 34.9 2.7 2.5 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 EKX46917.1 - 5e-08 32.2 3.1 0.00012 21.1 1.8 2.4 2 1 0 2 2 2 2 MFS_1 like family MFS_4 PF06779.14 EKX46917.1 - 3.1e-06 26.8 4.3 3.1e-06 26.8 4.3 2.8 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 EKX46917.1 - 0.00071 18.1 11.4 0.00094 17.7 1.8 3.1 2 2 1 3 3 3 2 Transmembrane secretion effector MFS_2 PF13347.6 EKX46917.1 - 0.047 12.2 3.6 0.048 12.2 0.4 2.3 2 1 1 3 3 3 0 MFS/sugar transport protein LRR_6 PF13516.6 EKX46918.1 - 6.8e-30 100.6 24.0 7.4e-05 22.5 0.1 9.9 10 0 0 10 10 10 8 Leucine Rich repeat LRR_4 PF12799.7 EKX46918.1 - 6.4e-12 45.5 15.8 0.0046 17.4 0.3 5.8 3 2 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX46918.1 - 2.8e-06 27.1 9.0 2 9.3 0.0 7.8 9 0 0 9 9 9 1 Leucine Rich Repeat LRR_8 PF13855.6 EKX46918.1 - 0.00019 21.1 23.7 1.2 9.0 1.0 6.4 2 2 0 3 3 3 3 Leucine rich repeat Lem_TRP PF08262.11 EKX46918.1 - 1 9.5 5.0 2.4 8.3 5.0 1.6 1 0 0 1 1 1 0 Leucophaea maderae tachykinin-related peptide BBS1 PF14779.6 EKX46920.1 - 4.5e-82 275.3 0.1 7e-80 268.1 0.0 2.2 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 1 BBS2_Mid PF14783.6 EKX46920.1 - 3.9e-08 33.3 0.0 0.028 14.4 0.0 3.5 3 1 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region PHTB1_N PF14727.6 EKX46920.1 - 0.0039 16.6 0.3 2.5 7.3 0.1 2.8 2 1 1 3 3 3 2 PTHB1 N-terminus PPPI_inhib PF14895.6 EKX46920.1 - 0.038 13.1 0.1 0.069 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein phosphatase 1 inhibitor RRM_1 PF00076.22 EKX46921.1 - 9.6e-16 57.4 0.0 5.1e-15 55.0 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EKX46921.1 - 0.0001 22.1 0.0 0.00037 20.3 0.0 1.9 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_3 PF08777.11 EKX46921.1 - 0.046 13.8 4.5 0.64 10.1 0.0 3.7 3 0 0 3 3 3 0 RNA binding motif Lsm_interact PF05391.11 EKX46921.1 - 0.12 11.9 0.4 0.28 10.7 0.4 1.6 1 0 0 1 1 1 0 Lsm interaction motif RCC1 PF00415.18 EKX46922.1 - 1.6e-79 262.4 30.3 9.2e-16 58.2 1.5 6.0 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX46922.1 - 5.1e-41 137.7 30.2 1.1e-09 37.9 0.1 6.2 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.6 EKX46922.1 - 0.2 11.9 0.5 5.3 7.3 0.0 3.0 3 1 0 3 3 3 0 Putative heavy-metal chelation DUF962 PF06127.11 EKX46924.1 - 9.3e-06 25.7 0.2 8.9e-05 22.5 0.0 2.7 2 2 0 2 2 2 1 Protein of unknown function (DUF962) PEMT PF04191.13 EKX46924.1 - 0.00013 22.3 0.8 0.00013 22.3 0.8 3.2 3 0 0 3 3 3 1 Phospholipid methyltransferase Med31 PF05669.12 EKX46924.1 - 0.48 10.5 5.9 0.57 10.2 0.5 3.3 3 0 0 3 3 3 0 SOH1 HSP70 PF00012.20 EKX46925.1 - 1.1e-51 175.8 0.1 3.5e-51 174.1 0.1 1.6 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EKX46925.1 - 0.00049 19.0 0.1 0.0072 15.2 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EKX46925.1 - 0.056 13.2 0.0 0.25 11.0 0.0 2.2 2 1 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain SPRY PF00622.28 EKX46931.1 - 7.1e-13 48.7 0.1 5.1e-07 29.8 0.0 2.4 2 0 0 2 2 2 2 SPRY domain DDHD PF02862.17 EKX46931.1 - 0.014 15.6 0.1 0.063 13.4 0.1 1.9 1 1 0 1 1 1 0 DDHD domain Thiolase_N PF00108.23 EKX46932.1 - 2.4e-21 76.2 5.9 5.8e-20 71.7 5.9 2.2 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EKX46932.1 - 1.6e-08 34.2 0.3 8.1e-08 32.0 0.2 2.3 2 1 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 EKX46932.1 - 0.0002 21.1 0.9 0.021 14.6 0.2 2.5 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 EKX46932.1 - 0.12 11.9 6.8 0.021 14.4 1.9 2.2 3 0 0 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain DUF1604 PF07713.13 EKX46934.1 - 0.032 14.1 0.6 0.067 13.0 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) NOA36 PF06524.12 EKX46934.1 - 0.33 10.2 3.3 0.41 9.9 3.3 1.1 1 0 0 1 1 1 0 NOA36 protein Ion_trans PF00520.31 EKX46936.1 - 1.3e-33 116.3 14.1 1.8e-33 115.8 14.1 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EKX46936.1 - 4.5e-08 32.2 4.2 4.5e-08 32.2 4.2 2.1 1 1 1 2 2 2 2 Polycystin cation channel EF-hand_1 PF00036.32 EKX46936.1 - 0.05 13.2 0.1 0.13 11.8 0.1 1.8 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 EKX46936.1 - 0.083 12.9 0.0 0.29 11.2 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 EKX46936.1 - 0.11 13.0 0.2 0.33 11.4 0.2 1.8 1 0 0 1 1 1 0 EF-hand domain pair Tcp10_C PF07202.13 EKX46938.1 - 3e-31 108.7 0.2 3.2e-31 108.6 0.2 1.0 1 0 0 1 1 1 1 T-complex protein 10 C-terminus Surfac_D-trimer PF09006.11 EKX46938.1 - 0.63 10.0 2.2 13 5.8 0.1 3.4 1 1 2 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation IBN_N PF03810.19 EKX46939.1 - 4.9e-07 29.6 0.5 1.8e-06 27.7 0.5 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain RIX1 PF08167.12 EKX46939.1 - 0.0068 16.2 1.6 3.7 7.2 0.1 3.3 3 0 0 3 3 3 2 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 EKX46939.1 - 0.62 9.6 8.2 0.67 9.5 0.3 4.2 4 1 0 5 5 5 0 CLASP N terminal Nucleolin_bd PF16725.5 EKX46940.1 - 0.004 16.8 0.3 0.015 15.0 0.1 2.0 2 0 0 2 2 2 1 Nucleolin binding domain AAA_11 PF13086.6 EKX46941.1 - 5.1e-06 26.5 6.9 0.00011 22.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EKX46941.1 - 0.00081 19.8 1.3 0.0063 16.9 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EKX46941.1 - 0.0011 18.7 0.0 0.003 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Pox_A22 PF04848.13 EKX46941.1 - 0.0015 18.7 0.0 0.0032 17.6 0.0 1.5 1 0 0 1 1 1 1 Poxvirus A22 protein AAA_25 PF13481.6 EKX46941.1 - 0.0064 16.1 0.0 0.028 14.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EKX46941.1 - 0.029 14.1 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mt_ATP-synt_B PF05405.14 EKX46941.1 - 0.029 14.0 6.0 0.055 13.1 6.0 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Rad17 PF03215.15 EKX46941.1 - 0.037 13.9 0.0 0.094 12.6 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain MscS_porin PF12795.7 EKX46941.1 - 0.044 13.3 10.2 0.083 12.4 10.2 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain ResIII PF04851.15 EKX46941.1 - 0.05 13.6 3.7 1.4 8.9 0.0 3.0 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit ATP-grasp_4 PF13535.6 EKX46941.1 - 0.065 12.8 0.7 0.3 10.7 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain CbiA PF01656.23 EKX46941.1 - 0.082 13.0 0.1 0.19 11.8 0.0 1.8 2 0 0 2 2 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.7 EKX46941.1 - 0.087 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 EKX46941.1 - 0.089 13.2 0.6 0.35 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Exonuc_VII_L PF02601.15 EKX46941.1 - 0.1 12.2 7.7 0.3 10.6 6.7 2.2 3 0 0 3 3 2 0 Exonuclease VII, large subunit YkyA PF10368.9 EKX46941.1 - 0.1 12.3 6.9 0.22 11.2 6.9 1.5 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein AAA_5 PF07728.14 EKX46941.1 - 0.11 12.5 0.1 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) YmdB PF13277.6 EKX46941.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 YmdB-like protein Golgin_A5 PF09787.9 EKX46941.1 - 0.15 11.5 12.7 0.25 10.8 12.7 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Lipase_chap PF03280.14 EKX46941.1 - 0.21 11.5 13.2 0.36 10.8 13.2 1.2 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein DUF4407 PF14362.6 EKX46941.1 - 0.33 10.3 6.3 0.59 9.4 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) COG5 PF10392.9 EKX46941.1 - 0.45 10.7 5.2 9.5 6.4 4.2 2.3 1 1 1 2 2 2 0 Golgi transport complex subunit 5 TPR_MLP1_2 PF07926.12 EKX46941.1 - 0.56 10.3 17.3 1.8 8.6 5.3 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 EKX46941.1 - 0.69 8.9 5.5 1.6 7.8 5.5 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF948 PF06103.11 EKX46941.1 - 0.77 10.1 3.5 2.1 8.7 1.8 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) AAA_18 PF13238.6 EKX46941.1 - 0.86 10.2 0.0 0.86 10.2 0.0 2.9 3 2 1 4 4 2 0 AAA domain DUF1664 PF07889.12 EKX46941.1 - 0.87 9.6 9.0 5.7 7.0 3.4 2.7 2 1 0 3 3 2 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 EKX46941.1 - 1 9.6 16.0 1 9.6 4.0 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Phage_GPO PF05929.11 EKX46941.1 - 1.1 8.8 5.8 2 7.9 5.8 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase GAS PF13851.6 EKX46941.1 - 1.1 8.5 18.8 3.3 7.0 18.8 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding She9_MDM33 PF05546.11 EKX46941.1 - 1.2 9.0 8.7 1.9 8.2 8.7 1.3 1 0 0 1 1 1 0 She9 / Mdm33 family DUF1465 PF07323.12 EKX46941.1 - 1.3 8.8 7.4 0.51 10.2 3.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1465) Laminin_I PF06008.14 EKX46941.1 - 1.4 8.5 10.7 0.16 11.7 2.2 2.2 1 1 1 2 2 2 0 Laminin Domain I EzrA PF06160.12 EKX46941.1 - 1.8 6.6 12.5 0.33 9.1 6.2 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA IFT57 PF10498.9 EKX46941.1 - 2 7.3 13.4 2.7 6.9 1.8 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF737 PF05300.11 EKX46941.1 - 2.1 8.7 14.8 0.65 10.3 11.8 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF737) Phage_HK97_TLTM PF06120.11 EKX46941.1 - 2.5 7.2 9.5 4.6 6.3 9.5 1.3 1 0 0 1 1 1 0 Tail length tape measure protein ATPase PF06745.13 EKX46941.1 - 2.9 7.2 6.4 4.6 6.5 0.0 2.5 2 1 0 2 2 2 0 KaiC FapA PF03961.13 EKX46941.1 - 3 6.3 12.5 7.7 5.0 12.6 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 EKX46941.1 - 3 8.0 11.1 8 6.6 11.1 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ZapB PF06005.12 EKX46941.1 - 3.3 8.2 20.2 2.9 8.4 4.9 2.6 2 0 0 2 2 2 0 Cell division protein ZapB Laminin_II PF06009.12 EKX46941.1 - 3.5 7.6 8.7 7.8 6.5 8.7 1.6 1 0 0 1 1 1 0 Laminin Domain II ParB PF08775.10 EKX46941.1 - 3.6 8.1 7.4 46 4.5 7.1 2.7 2 1 0 2 2 2 0 ParB family SKA2 PF16740.5 EKX46941.1 - 4.1 7.2 9.7 9.3 6.1 2.3 2.5 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Spc7 PF08317.11 EKX46941.1 - 4.4 6.1 17.9 0.88 8.4 10.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Occludin_ELL PF07303.13 EKX46941.1 - 4.8 8.0 9.5 2.1 9.1 3.8 2.5 1 1 1 2 2 2 0 Occludin homology domain Troponin PF00992.20 EKX46941.1 - 9 6.6 18.3 1.8 8.9 14.2 1.9 1 1 0 1 1 1 0 Troponin AAA_11 PF13086.6 EKX46942.1 - 1.7e-06 28.1 8.2 0.0001 22.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain GAS PF13851.6 EKX46942.1 - 3.1e-05 23.4 17.3 5.4e-05 22.6 17.3 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding AAA_30 PF13604.6 EKX46942.1 - 0.001 18.8 0.0 0.0029 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EKX46942.1 - 0.0026 18.2 4.4 0.0049 17.3 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EKX46942.1 - 0.0053 17.3 0.6 1.3 9.5 0.0 2.5 2 0 0 2 2 2 1 ABC transporter FapA PF03961.13 EKX46942.1 - 0.007 15.0 9.7 0.011 14.4 9.7 1.2 1 0 0 1 1 1 1 Flagellar Assembly Protein A Golgin_A5 PF09787.9 EKX46942.1 - 0.011 15.3 14.8 0.017 14.6 14.8 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 AAA_25 PF13481.6 EKX46942.1 - 0.011 15.4 1.3 0.032 13.8 0.0 2.4 2 1 1 3 3 1 0 AAA domain CALCOCO1 PF07888.11 EKX46942.1 - 0.012 14.5 12.8 0.018 13.9 12.8 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Phage_HK97_TLTM PF06120.11 EKX46942.1 - 0.014 14.6 9.9 0.025 13.8 9.9 1.3 1 0 0 1 1 1 0 Tail length tape measure protein Prominin PF05478.11 EKX46942.1 - 0.015 13.3 4.1 0.022 12.7 4.1 1.1 1 0 0 1 1 1 0 Prominin Cauli_DNA-bind PF03310.13 EKX46942.1 - 0.018 15.1 4.6 0.035 14.2 4.6 1.5 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein ZapB PF06005.12 EKX46942.1 - 0.018 15.4 22.0 0.34 11.4 8.7 2.5 2 0 0 2 2 2 0 Cell division protein ZapB DUF2884 PF11101.8 EKX46942.1 - 0.019 14.5 7.5 1.6 8.2 8.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) IstB_IS21 PF01695.17 EKX46942.1 - 0.019 14.7 0.0 0.062 13.0 0.0 1.8 2 0 0 2 2 1 0 IstB-like ATP binding protein Exonuc_VII_L PF02601.15 EKX46942.1 - 0.022 14.4 7.6 0.064 12.8 6.6 2.2 3 0 0 3 3 2 0 Exonuclease VII, large subunit AAA_18 PF13238.6 EKX46942.1 - 0.023 15.2 2.0 0.091 13.3 0.0 2.7 3 1 0 3 3 1 0 AAA domain Tektin PF03148.14 EKX46942.1 - 0.042 12.6 17.2 0.08 11.7 17.2 1.3 1 0 0 1 1 1 0 Tektin family Atg14 PF10186.9 EKX46942.1 - 0.045 12.8 6.9 0.098 11.7 6.9 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FH2 PF02181.23 EKX46942.1 - 0.049 12.7 9.2 0.073 12.2 9.2 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain CbiA PF01656.23 EKX46942.1 - 0.066 13.3 0.2 0.17 11.9 0.0 1.9 2 0 0 2 2 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.7 EKX46942.1 - 0.068 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region APG17 PF04108.12 EKX46942.1 - 0.069 12.3 6.1 0.11 11.6 6.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 HOOK PF05622.12 EKX46942.1 - 0.079 11.1 15.3 0.12 10.5 15.3 1.1 1 0 0 1 1 1 0 HOOK protein YmdB PF13277.6 EKX46942.1 - 0.086 12.2 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 YmdB-like protein DUF948 PF06103.11 EKX46942.1 - 0.091 13.0 6.6 0.15 12.3 4.8 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) ResIII PF04851.15 EKX46942.1 - 0.099 12.6 5.7 1.4 8.9 0.0 3.0 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Lebercilin PF15619.6 EKX46942.1 - 0.099 12.3 19.2 0.23 11.1 19.2 1.5 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease SKA2 PF16740.5 EKX46942.1 - 0.11 12.3 14.7 0.62 9.9 5.8 2.4 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Aminotran_3 PF00202.21 EKX46942.1 - 0.11 11.1 0.7 0.18 10.4 0.7 1.2 1 0 0 1 1 1 0 Aminotransferase class-III Laminin_II PF06009.12 EKX46942.1 - 0.11 12.5 11.3 0.24 11.4 11.3 1.5 1 0 0 1 1 1 0 Laminin Domain II T3SSipB PF16535.5 EKX46942.1 - 0.14 12.6 2.5 0.45 11.0 2.7 1.6 2 0 0 2 2 1 0 Type III cell invasion protein SipB AAA_24 PF13479.6 EKX46942.1 - 0.15 11.8 0.7 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EKX46942.1 - 0.17 12.3 1.0 0.37 11.1 0.0 2.1 2 0 0 2 2 1 0 AAA ATPase domain LMBR1 PF04791.16 EKX46942.1 - 0.17 10.8 4.1 0.25 10.2 4.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.6 EKX46942.1 - 0.17 11.2 6.0 0.33 10.3 6.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 EKX46942.1 - 0.17 11.9 14.2 1.9 8.5 7.0 2.5 2 1 0 2 2 1 0 Protein of unknown function (DUF1664) FAM76 PF16046.5 EKX46942.1 - 0.19 11.1 6.0 0.31 10.3 6.0 1.3 1 0 0 1 1 1 0 FAM76 protein DegS PF05384.11 EKX46942.1 - 0.19 11.2 18.3 0.33 10.4 18.3 1.3 1 0 0 1 1 1 0 Sensor protein DegS DivIC PF04977.15 EKX46942.1 - 0.21 11.4 21.0 0.76 9.6 10.5 2.4 2 0 0 2 2 2 0 Septum formation initiator Seryl_tRNA_N PF02403.22 EKX46942.1 - 0.29 11.4 17.4 0.67 10.2 6.8 2.2 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain IFT57 PF10498.9 EKX46942.1 - 0.35 9.8 14.1 0.53 9.2 14.1 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 AAA_22 PF13401.6 EKX46942.1 - 0.36 11.1 3.0 0.54 10.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain DUF3584 PF12128.8 EKX46942.1 - 0.45 8.0 15.1 0.65 7.4 15.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3552 PF12072.8 EKX46942.1 - 0.47 9.8 18.6 0.81 9.1 18.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Spc7 PF08317.11 EKX46942.1 - 0.48 9.3 21.0 0.32 9.9 11.7 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Serine_rich PF08824.10 EKX46942.1 - 0.49 10.4 4.7 1.4 8.9 4.2 1.9 2 0 0 2 2 1 0 Serine rich protein interaction domain ATPase PF06745.13 EKX46942.1 - 0.52 9.6 6.7 4.6 6.5 0.0 2.3 2 0 0 2 2 2 0 KaiC She9_MDM33 PF05546.11 EKX46942.1 - 0.52 10.1 11.9 0.9 9.3 11.9 1.3 1 0 0 1 1 1 0 She9 / Mdm33 family RmuC PF02646.16 EKX46942.1 - 0.54 9.3 8.9 0.4 9.8 7.3 1.5 1 1 0 1 1 1 0 RmuC family COG6 PF06419.11 EKX46942.1 - 0.61 8.2 9.7 0.96 7.6 9.7 1.2 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 YabA PF06156.13 EKX46942.1 - 0.87 10.3 15.0 5.7 7.6 7.8 2.5 1 1 1 2 2 2 0 Initiation control protein YabA Baculo_PEP_C PF04513.12 EKX46942.1 - 0.87 9.6 4.1 4.3 7.4 4.1 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1043 PF06295.12 EKX46942.1 - 1.1 9.3 6.1 2.2 8.3 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) FTA4 PF13093.6 EKX46942.1 - 1.2 9.0 10.8 2.5 7.9 10.8 1.4 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 APG6_N PF17675.1 EKX46942.1 - 1.3 9.6 22.5 80 3.8 22.2 2.3 1 1 0 1 1 1 0 Apg6 coiled-coil region MCPsignal PF00015.21 EKX46942.1 - 1.4 8.7 7.5 2.4 7.9 7.5 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain EzrA PF06160.12 EKX46942.1 - 1.4 7.0 16.0 4.3 5.4 16.0 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Vps53_N PF04100.12 EKX46942.1 - 1.5 7.7 8.7 3.2 6.6 8.4 1.6 1 1 0 1 1 1 0 Vps53-like, N-terminal Apolipoprotein PF01442.18 EKX46942.1 - 1.6 8.6 15.8 3.2 7.6 15.8 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain TPR_MLP1_2 PF07926.12 EKX46942.1 - 1.9 8.6 18.1 10 6.2 18.1 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Allexi_40kDa PF05549.11 EKX46942.1 - 2 7.9 5.5 3.4 7.1 5.5 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein AcylCoA_dehyd_C PF12186.8 EKX46942.1 - 2 8.6 6.1 4.4 7.5 4.4 2.4 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase C terminal V_ATPase_I PF01496.19 EKX46942.1 - 2.1 6.1 10.6 3 5.6 10.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HAUS5 PF14817.6 EKX46942.1 - 2.2 7.0 15.8 3.3 6.3 15.8 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 bZIP_1 PF00170.21 EKX46942.1 - 2.3 8.4 15.6 0.14 12.2 1.9 2.5 2 0 0 2 2 2 0 bZIP transcription factor CENP-H PF05837.12 EKX46942.1 - 2.4 8.6 19.0 22 5.5 17.2 2.8 2 1 0 2 2 2 0 Centromere protein H (CENP-H) DUF4201 PF13870.6 EKX46942.1 - 3.1 7.5 19.2 5.5 6.7 19.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF4208 PF13907.6 EKX46942.1 - 3.4 8.2 9.9 21 5.7 7.0 3.1 3 0 0 3 3 2 0 Domain of unknown function (DUF4208) DivIVA PF05103.13 EKX46942.1 - 3.4 7.8 15.0 1.8e+02 2.2 15.0 2.3 1 1 0 1 1 1 0 DivIVA protein Phage_GPO PF05929.11 EKX46942.1 - 4.7 6.8 6.2 8.8 5.9 6.2 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Prefoldin_2 PF01920.20 EKX46942.1 - 4.7 7.2 23.4 1.1e+02 2.8 23.2 2.5 1 1 0 1 1 1 0 Prefoldin subunit Fmp27_WPPW PF10359.9 EKX46942.1 - 4.8 5.9 10.0 9.2 5.0 10.0 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Nup88 PF10168.9 EKX46942.1 - 5.1 4.8 11.4 7.6 4.2 11.4 1.2 1 0 0 1 1 1 0 Nuclear pore component DUF812 PF05667.11 EKX46942.1 - 6.3 5.6 19.6 13 4.5 19.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Nup54 PF13874.6 EKX46942.1 - 6.4 6.9 15.1 14 5.8 15.1 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Lipase_chap PF03280.14 EKX46942.1 - 6.5 6.7 13.1 11 5.9 13.1 1.2 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein DUF1192 PF06698.11 EKX46942.1 - 6.6 6.9 6.8 1.6 8.9 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) OmpH PF03938.14 EKX46942.1 - 6.9 7.0 16.7 13 6.1 16.7 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TMPIT PF07851.13 EKX46942.1 - 7.4 5.7 12.8 19 4.4 12.8 1.6 1 1 0 1 1 1 0 TMPIT-like protein FlaC_arch PF05377.11 EKX46942.1 - 7.6 7.0 13.5 0.69 10.4 7.7 2.2 2 0 0 2 2 1 0 Flagella accessory protein C (FlaC) Tho2 PF11262.8 EKX46942.1 - 7.9 5.6 11.5 1.7 7.8 7.7 1.6 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 LPP PF04728.13 EKX46942.1 - 8.1 6.9 6.5 9.4 6.7 2.7 2.3 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Occludin_ELL PF07303.13 EKX46942.1 - 8.2 7.2 11.8 3 8.6 6.4 2.4 1 1 1 2 2 2 0 Occludin homology domain HisKA_3 PF07730.13 EKX46942.1 - 8.3 7.0 8.8 0.79 10.3 0.9 2.9 3 0 0 3 3 2 0 Histidine kinase Syntaxin_2 PF14523.6 EKX46942.1 - 8.6 6.8 12.9 7.3 7.0 4.8 2.5 1 1 1 2 2 2 0 Syntaxin-like protein Fib_alpha PF08702.10 EKX46942.1 - 8.9 6.5 14.8 35 4.6 14.9 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family AAA_11 PF13086.6 EKX46943.1 - 1.9e-06 27.9 4.4 0.00011 22.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Spc7 PF08317.11 EKX46943.1 - 0.00033 19.6 13.3 0.00054 18.9 13.3 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA PF00004.29 EKX46943.1 - 0.00079 19.9 1.3 0.005 17.3 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EKX46943.1 - 0.0012 18.6 0.0 0.003 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain She9_MDM33 PF05546.11 EKX46943.1 - 0.0031 17.4 6.6 0.0051 16.6 6.6 1.3 1 0 0 1 1 1 1 She9 / Mdm33 family ABC_tran PF00005.27 EKX46943.1 - 0.0032 18.0 0.7 1.4 9.5 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.6 EKX46943.1 - 0.0045 17.5 11.4 0.07 13.6 9.0 2.3 2 0 0 2 2 2 1 AAA domain Ran-binding PF05508.11 EKX46943.1 - 0.0047 16.0 3.7 0.0071 15.4 3.7 1.2 1 0 0 1 1 1 1 RanGTP-binding protein AAA_25 PF13481.6 EKX46943.1 - 0.0057 16.2 0.1 0.033 13.8 0.0 2.2 1 1 1 2 2 1 1 AAA domain FmiP_Thoc5 PF09766.9 EKX46943.1 - 0.0068 15.7 5.8 0.013 14.8 5.8 1.4 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 AAA_13 PF13166.6 EKX46943.1 - 0.012 14.2 8.4 0.024 13.3 8.4 1.3 1 0 0 1 1 1 0 AAA domain Laminin_I PF06008.14 EKX46943.1 - 0.013 15.2 5.7 0.024 14.3 5.7 1.4 1 0 0 1 1 1 0 Laminin Domain I ZapB PF06005.12 EKX46943.1 - 0.017 15.5 11.5 0.017 15.5 11.5 2.4 2 0 0 2 2 2 0 Cell division protein ZapB AAA_18 PF13238.6 EKX46943.1 - 0.018 15.6 0.2 0.094 13.3 0.0 2.3 2 1 0 2 2 1 0 AAA domain Vps53_N PF04100.12 EKX46943.1 - 0.02 13.9 3.5 0.032 13.2 3.5 1.3 1 0 0 1 1 1 0 Vps53-like, N-terminal Tektin PF03148.14 EKX46943.1 - 0.02 13.6 11.4 0.035 12.9 11.4 1.3 1 0 0 1 1 1 0 Tektin family T3SSipB PF16535.5 EKX46943.1 - 0.021 15.3 2.4 0.05 14.1 2.4 1.6 1 0 0 1 1 1 0 Type III cell invasion protein SipB IstB_IS21 PF01695.17 EKX46943.1 - 0.022 14.5 0.0 0.064 13.0 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein FapA PF03961.13 EKX46943.1 - 0.022 13.4 9.4 0.035 12.7 9.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Filament PF00038.21 EKX46943.1 - 0.024 14.2 9.0 0.041 13.4 9.0 1.3 1 0 0 1 1 1 0 Intermediate filament protein Sec8_exocyst PF04048.14 EKX46943.1 - 0.026 14.4 3.0 0.059 13.2 3.0 1.6 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain MCPsignal PF00015.21 EKX46943.1 - 0.035 13.9 5.4 0.06 13.2 5.4 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain APG17 PF04108.12 EKX46943.1 - 0.035 13.2 5.0 0.052 12.7 5.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 FlxA PF14282.6 EKX46943.1 - 0.049 13.6 12.0 0.11 12.4 12.0 1.5 1 0 0 1 1 1 0 FlxA-like protein TMPIT PF07851.13 EKX46943.1 - 0.053 12.8 7.6 0.087 12.1 7.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein Occludin_ELL PF07303.13 EKX46943.1 - 0.06 14.1 3.8 0.15 12.8 3.8 1.7 1 0 0 1 1 1 0 Occludin homology domain CbiA PF01656.23 EKX46943.1 - 0.061 13.4 0.1 0.18 11.9 0.0 1.9 2 0 0 2 2 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Exonuc_VII_L PF02601.15 EKX46943.1 - 0.062 12.9 5.5 0.11 12.1 3.9 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit AAA_7 PF12775.7 EKX46943.1 - 0.069 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF745 PF05335.13 EKX46943.1 - 0.076 12.7 7.9 0.13 12.0 7.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DLP_helical PF18709.1 EKX46943.1 - 0.076 12.2 8.7 0.13 11.4 8.7 1.3 1 0 0 1 1 1 0 Dynamin-like helical domain EzrA PF06160.12 EKX46943.1 - 0.08 11.1 9.2 0.11 10.6 9.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Phage_HK97_TLTM PF06120.11 EKX46943.1 - 0.082 12.1 7.5 0.15 11.3 7.5 1.3 1 0 0 1 1 1 0 Tail length tape measure protein AAA_16 PF13191.6 EKX46943.1 - 0.09 13.2 0.8 0.38 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Laminin_II PF06009.12 EKX46943.1 - 0.09 12.8 8.2 0.29 11.2 8.1 1.7 1 1 0 1 1 1 0 Laminin Domain II MscS_porin PF12795.7 EKX46943.1 - 0.095 12.2 9.1 0.17 11.4 9.1 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF812 PF05667.11 EKX46943.1 - 0.099 11.5 11.7 0.15 11.0 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Cauli_AT PF03233.13 EKX46943.1 - 0.11 12.4 3.1 0.23 11.4 3.1 1.5 1 0 0 1 1 1 0 Aphid transmission protein Atg14 PF10186.9 EKX46943.1 - 0.12 11.4 8.4 0.2 10.7 8.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cbl_N PF02262.16 EKX46943.1 - 0.14 12.2 0.8 0.31 11.0 0.8 1.6 1 0 0 1 1 1 0 CBL proto-oncogene N-terminal domain 1 ResIII PF04851.15 EKX46943.1 - 0.15 12.1 3.9 1.5 8.8 0.0 3.0 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Prominin PF05478.11 EKX46943.1 - 0.15 10.0 1.4 0.21 9.5 1.4 1.1 1 0 0 1 1 1 0 Prominin GAS PF13851.6 EKX46943.1 - 0.15 11.4 15.8 0.26 10.6 15.8 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 EKX46943.1 - 0.15 12.2 6.9 0.31 11.2 6.9 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ISG65-75 PF11727.8 EKX46943.1 - 0.15 11.3 5.2 0.26 10.5 5.2 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein AAA_24 PF13479.6 EKX46943.1 - 0.16 11.7 0.7 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EKX46943.1 - 0.17 12.2 1.0 0.54 10.5 0.0 2.3 2 1 0 2 2 1 0 AAA domain ATPase PF06745.13 EKX46943.1 - 0.18 11.2 5.6 4.7 6.5 0.0 2.3 2 0 0 2 2 2 0 KaiC IF-2B PF01008.17 EKX46943.1 - 0.2 10.8 2.1 0.33 10.1 2.1 1.2 1 0 0 1 1 1 0 Initiation factor 2 subunit family OmpH PF03938.14 EKX46943.1 - 0.32 11.3 13.3 0.54 10.6 13.3 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) V_ATPase_I PF01496.19 EKX46943.1 - 0.33 8.8 3.9 0.46 8.3 3.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF948 PF06103.11 EKX46943.1 - 0.36 11.1 3.3 0.95 9.8 3.3 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) ApoLp-III PF07464.11 EKX46943.1 - 0.38 10.8 12.8 0.79 9.8 12.8 1.5 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF2203 PF09969.9 EKX46943.1 - 0.4 11.4 6.3 1.3 9.8 6.3 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF4715 PF15835.5 EKX46943.1 - 0.41 10.7 10.1 2.1 8.4 7.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4715) LMBR1 PF04791.16 EKX46943.1 - 0.43 9.4 0.9 0.63 8.9 0.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein IFT57 PF10498.9 EKX46943.1 - 0.46 9.4 13.0 0.33 9.9 11.4 1.5 1 1 1 2 2 1 0 Intra-flagellar transport protein 57 FAM76 PF16046.5 EKX46943.1 - 0.51 9.6 4.3 0.87 8.9 4.3 1.3 1 0 0 1 1 1 0 FAM76 protein FH2 PF02181.23 EKX46943.1 - 0.53 9.4 5.9 0.79 8.8 5.9 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain HisKA_3 PF07730.13 EKX46943.1 - 0.59 10.7 2.9 15 6.2 2.2 3.0 2 1 1 3 3 3 0 Histidine kinase DUF3584 PF12128.8 EKX46943.1 - 0.6 7.6 9.9 0.86 7.0 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 EKX46943.1 - 0.6 10.2 10.1 2.4 8.2 10.3 2.0 2 1 0 2 2 1 0 Protein of unknown function (DUF1664) DUF4200 PF13863.6 EKX46943.1 - 0.66 10.4 15.5 1.5 9.3 15.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF3450 PF11932.8 EKX46943.1 - 0.67 9.2 9.8 1.1 8.5 9.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Ufd2P_core PF10408.9 EKX46943.1 - 0.78 8.3 3.3 1.2 7.7 3.3 1.1 1 0 0 1 1 1 0 Ubiquitin elongating factor core Seryl_tRNA_N PF02403.22 EKX46943.1 - 0.85 9.9 14.2 1 9.6 12.9 1.7 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Zw10 PF06248.13 EKX46943.1 - 0.87 8.1 5.2 1.3 7.5 5.2 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Mod_r PF07200.13 EKX46943.1 - 0.89 9.7 9.7 1.8 8.7 9.7 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Fmp27_WPPW PF10359.9 EKX46943.1 - 1 8.2 8.5 1.5 7.6 8.5 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Spore_III_AB PF09548.10 EKX46943.1 - 1.3 9.2 7.5 0.94 9.6 5.4 1.8 2 0 0 2 2 1 0 Stage III sporulation protein AB (spore_III_AB) FlaC_arch PF05377.11 EKX46943.1 - 1.4 9.4 11.0 2.6 8.5 4.4 2.4 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) XhlA PF10779.9 EKX46943.1 - 1.5 9.0 14.3 0.63 10.3 7.0 2.9 2 1 1 3 3 2 0 Haemolysin XhlA TPR_MLP1_2 PF07926.12 EKX46943.1 - 1.8 8.6 14.8 4.4 7.4 14.6 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein GrpE PF01025.19 EKX46943.1 - 1.8 8.2 11.3 1.6 8.4 9.0 2.0 2 0 0 2 2 1 0 GrpE DUF4407 PF14362.6 EKX46943.1 - 1.9 7.8 3.9 3 7.1 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5344 PF17279.2 EKX46943.1 - 2 9.1 9.2 5.2 7.7 9.2 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5344) Apolipoprotein PF01442.18 EKX46943.1 - 2.1 8.2 14.2 4.5 7.1 14.2 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Tho2 PF11262.8 EKX46943.1 - 2.2 7.4 8.0 3.3 6.8 8.0 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF773 PF05600.12 EKX46943.1 - 2.4 6.8 10.6 3.8 6.1 10.6 1.2 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 PhaP_Bmeg PF09602.10 EKX46943.1 - 2.9 7.8 11.5 9.8 6.1 11.5 1.9 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) CENP-H PF05837.12 EKX46943.1 - 3 8.3 11.0 4.3 7.8 9.9 1.9 2 0 0 2 2 1 0 Centromere protein H (CENP-H) Med9 PF07544.13 EKX46943.1 - 3.2 7.9 10.1 35 4.6 9.8 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 5_nucleotid PF05761.14 EKX46943.1 - 3.3 6.5 4.6 5.1 5.9 4.6 1.2 1 0 0 1 1 1 0 5' nucleotidase family Snapin_Pallidin PF14712.6 EKX46943.1 - 3.4 8.2 13.3 4.1 7.9 11.9 2.0 1 1 0 1 1 1 0 Snapin/Pallidin COG2 PF06148.11 EKX46943.1 - 3.9 7.6 9.6 7.5 6.6 8.8 1.8 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 LUC7 PF03194.15 EKX46943.1 - 4.3 6.9 10.4 6.9 6.3 10.4 1.2 1 0 0 1 1 1 0 LUC7 N_terminus Tropomyosin_1 PF12718.7 EKX46943.1 - 4.4 7.5 17.2 7.8 6.6 17.2 1.3 1 0 0 1 1 1 0 Tropomyosin like MobC PF05713.11 EKX46943.1 - 4.5 7.8 5.2 39 4.8 1.5 2.8 1 1 1 2 2 2 0 Bacterial mobilisation protein (MobC) YkyA PF10368.9 EKX46943.1 - 6.3 6.4 16.4 7.5 6.2 14.9 1.7 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein DivIC PF04977.15 EKX46943.1 - 8.1 6.3 16.3 1.3 8.9 10.1 2.2 1 1 0 1 1 1 0 Septum formation initiator Nup88 PF10168.9 EKX46943.1 - 9.3 3.9 12.3 14 3.4 12.3 1.1 1 0 0 1 1 1 0 Nuclear pore component Macoilin PF09726.9 EKX46943.1 - 9.9 4.6 9.2 16 3.9 9.2 1.2 1 0 0 1 1 1 0 Macoilin family SAM_1 PF00536.30 EKX46945.1 - 0.00026 21.4 0.0 0.00056 20.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TPR_1 PF00515.28 EKX46945.1 - 0.0066 16.2 0.1 0.81 9.6 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX46945.1 - 0.025 14.6 0.1 5.5 7.4 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4398 PF14346.6 EKX46945.1 - 0.19 12.4 9.1 0.19 12.4 1.7 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4398) PH_11 PF15413.6 EKX46945.1 - 1.9 9.0 6.2 0.37 11.3 0.3 2.5 2 1 1 3 3 3 0 Pleckstrin homology domain SAM_1 PF00536.30 EKX46946.1 - 1.4e-22 79.9 0.1 3.3e-14 53.1 0.2 2.7 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EKX46946.1 - 6e-22 77.5 0.3 4.1e-11 42.8 0.0 3.1 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) Aida_C2 PF14186.6 EKX46946.1 - 0.00038 20.1 0.0 0.00091 18.9 0.0 1.6 1 0 0 1 1 1 1 Cytoskeletal adhesion zf-NOSIP PF15906.5 EKX46946.1 - 0.00083 19.4 0.0 0.0021 18.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein U-box PF04564.15 EKX46946.1 - 0.0025 17.9 0.0 0.0081 16.3 0.0 1.9 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX46946.1 - 0.0046 16.7 0.0 0.015 15.1 0.0 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PAP2 PF01569.21 EKX46947.1 - 3.2e-21 75.5 2.1 3.2e-21 75.5 2.1 1.6 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 EKX46947.1 - 0.8 9.4 8.8 1.5 8.4 0.5 2.5 2 1 0 2 2 2 0 PAP2 superfamily Aa_trans PF01490.18 EKX46948.1 - 5e-63 213.2 25.6 5.9e-63 213.0 25.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PCRF PF03462.18 EKX46949.1 - 1.3e-64 217.6 2.5 1.3e-64 217.6 0.5 1.9 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 EKX46949.1 - 1.1e-37 128.5 2.8 1.1e-37 128.5 2.8 1.8 2 0 0 2 2 2 1 RF-1 domain ABC_tran_CTD PF16326.5 EKX46949.1 - 0.014 15.7 12.8 0.28 11.5 0.0 3.6 4 0 0 4 4 4 0 ABC transporter C-terminal domain HR1 PF02185.16 EKX46949.1 - 0.015 15.4 6.9 0.023 14.8 0.2 2.8 2 0 0 2 2 2 0 Hr1 repeat M PF02370.16 EKX46949.1 - 0.067 13.8 6.5 0.07 13.7 3.5 2.8 2 0 0 2 2 2 0 M protein repeat MerR-DNA-bind PF09278.11 EKX46949.1 - 0.99 10.0 6.0 0.32 11.6 0.8 2.7 2 0 0 2 2 2 0 MerR, DNA binding CinA_KH PF18146.1 EKX46949.1 - 1.5 9.0 4.6 2.7 8.2 0.1 3.3 4 0 0 4 4 4 0 Damage-inducible protein CinA KH domain CCDC-167 PF15188.6 EKX46949.1 - 3.5 8.0 9.4 0.51 10.7 3.1 2.6 2 2 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4140 PF13600.6 EKX46949.1 - 4.6 7.7 6.2 2.8 8.5 0.1 2.7 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) PARP PF00644.20 EKX46950.1 - 1.8e-18 66.9 1.6 3.5e-17 62.7 0.0 2.9 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain DUF913 PF06025.12 EKX46950.1 - 0.0091 15.0 1.1 0.015 14.3 1.1 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) MRNIP PF15749.5 EKX46950.1 - 0.65 10.7 15.1 1.6 9.5 15.1 1.6 1 0 0 1 1 1 0 MRN-interacting protein RPA43_OB PF17875.1 EKX46950.1 - 1.3 9.7 10.4 4.1 8.1 10.4 1.8 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I Nop14 PF04147.12 EKX46950.1 - 1.6 6.8 16.0 2.4 6.3 16.0 1.1 1 0 0 1 1 1 0 Nop14-like family Spt20 PF12090.8 EKX46950.1 - 2.1 7.9 22.7 4.1 6.9 22.7 1.4 1 0 0 1 1 1 0 Spt20 family CDC45 PF02724.14 EKX46950.1 - 2.9 6.1 15.7 5.3 5.2 15.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Afi1 PF07792.12 EKX46950.1 - 4 7.9 13.2 8.4 6.9 13.2 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CPSF100_C PF13299.6 EKX46950.1 - 7.5 6.7 9.3 19 5.4 9.3 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Ank_2 PF12796.7 EKX46952.1 - 0.0003 21.3 0.0 0.00074 20.1 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX46952.1 - 0.00032 20.9 0.0 0.0009 19.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX46952.1 - 0.024 15.2 0.0 0.065 13.8 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 EKX46952.1 - 0.037 14.5 0.1 0.21 12.1 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 EKX46952.1 - 0.13 12.9 0.0 1.4 9.7 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 EKX46953.1 - 5.9e-11 42.8 0.0 5.6e-08 33.3 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX46953.1 - 3.4e-09 37.1 0.0 0.0027 18.3 0.0 4.2 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX46953.1 - 3.6e-07 30.3 0.0 1.8e-05 24.9 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX46953.1 - 6.8e-07 29.1 0.0 0.055 14.0 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 EKX46953.1 - 2.5e-06 27.6 0.0 0.0021 18.4 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat PH_15 PF17339.2 EKX46954.1 - 0.0016 18.3 0.1 0.0039 17.1 0.1 1.6 1 0 0 1 1 1 1 PH domain DUF2721 PF11026.8 EKX46954.1 - 0.47 10.3 4.7 1.1 9.2 4.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Na_Ca_ex PF01699.24 EKX46956.1 - 1.2e-42 145.4 37.3 2.9e-22 79.2 7.6 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Calx-beta PF03160.14 EKX46956.1 - 1.5e-28 98.9 0.7 9.6e-20 70.6 0.1 2.4 2 0 0 2 2 2 2 Calx-beta domain DUF4843 PF16132.5 EKX46956.1 - 0.0042 16.7 0.5 0.14 11.8 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4843) Thioredoxin PF00085.20 EKX46957.1 - 9.8e-15 54.4 0.0 1.4e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EKX46957.1 - 2.1e-05 24.0 0.1 2.6e-05 23.7 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 EKX46957.1 - 0.00023 21.1 0.1 0.00039 20.4 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_4 PF13462.6 EKX46957.1 - 0.001 19.3 0.2 0.034 14.3 0.3 2.0 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 EKX46957.1 - 0.0048 17.3 0.1 0.014 15.8 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain IQ PF00612.27 EKX46958.1 - 9.3e-17 59.2 35.0 0.0064 16.2 1.6 8.4 8 0 0 8 8 8 7 IQ calmodulin-binding motif AAA PF00004.29 EKX46960.1 - 5.4e-45 153.0 0.0 1.9e-44 151.3 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EKX46960.1 - 2.3e-09 37.1 0.6 1.7e-08 34.3 0.0 2.7 4 0 0 4 4 3 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 EKX46960.1 - 5.9e-09 36.3 0.0 1.4e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EKX46960.1 - 1.8e-08 34.5 0.1 5.7e-08 32.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 EKX46960.1 - 1e-07 31.6 0.0 2.4e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_18 PF13238.6 EKX46960.1 - 1.1e-05 26.0 0.0 5e-05 23.9 0.0 2.1 3 1 0 3 3 1 1 AAA domain AAA_16 PF13191.6 EKX46960.1 - 1.4e-05 25.6 0.2 0.0017 18.8 0.0 2.7 2 1 0 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 EKX46960.1 - 3.1e-05 23.8 0.0 0.00013 21.8 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EKX46960.1 - 6.2e-05 23.3 0.7 0.017 15.4 0.0 2.7 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 EKX46960.1 - 0.00012 21.3 0.2 0.00074 18.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) TIP49 PF06068.13 EKX46960.1 - 0.00062 19.1 0.0 0.0016 17.7 0.0 1.8 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 EKX46960.1 - 0.00088 19.6 0.0 0.002 18.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 EKX46960.1 - 0.0012 18.4 0.0 0.0029 17.2 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 EKX46960.1 - 0.0023 17.4 0.1 0.0048 16.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EKX46960.1 - 0.0029 17.9 0.0 0.0066 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 EKX46960.1 - 0.0033 17.4 0.0 0.013 15.5 0.0 1.9 1 1 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 EKX46960.1 - 0.0048 16.6 0.2 0.29 10.8 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 EKX46960.1 - 0.0056 16.5 0.0 0.03 14.2 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EKX46960.1 - 0.013 15.2 0.0 0.031 14.0 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 EKX46960.1 - 0.015 15.0 0.1 0.044 13.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EKX46960.1 - 0.017 15.1 0.0 0.21 11.5 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 EKX46960.1 - 0.027 14.5 0.1 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EKX46960.1 - 0.028 13.8 0.6 0.25 10.7 0.0 2.5 3 0 0 3 3 3 0 KaiC NTPase_1 PF03266.15 EKX46960.1 - 0.037 13.9 0.1 0.16 11.9 0.0 2.1 3 0 0 3 3 3 0 NTPase Parvo_NS1 PF01057.17 EKX46960.1 - 0.041 13.0 0.0 0.076 12.1 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 EKX46960.1 - 0.049 13.2 0.4 0.22 11.1 0.1 2.0 1 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EKX46960.1 - 0.065 12.9 0.1 0.15 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EKX46960.1 - 0.074 13.2 0.0 0.19 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EKX46960.1 - 0.085 13.3 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EKX46960.1 - 0.089 12.6 0.1 0.17 11.6 0.0 1.6 2 0 0 2 2 1 0 AAA domain SKI PF01202.22 EKX46960.1 - 0.096 12.8 0.1 11 6.1 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase DUF3450 PF11932.8 EKX46960.1 - 0.15 11.4 1.2 0.31 10.3 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FKBP_C PF00254.28 EKX46961.1 - 6.5e-21 74.5 0.0 1.5e-20 73.3 0.0 1.6 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N PF01346.18 EKX46961.1 - 4.8e-08 33.9 0.2 1.2e-07 32.6 0.2 1.7 2 0 0 2 2 2 1 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Ank_2 PF12796.7 EKX46962.1 - 1.3e-10 41.7 0.1 3e-10 40.6 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX46962.1 - 6.2e-08 33.0 0.1 1.6e-07 31.7 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX46962.1 - 1.4e-06 28.4 1.5 8.1e-06 26.0 0.6 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX46962.1 - 2.5e-05 24.5 1.7 0.0053 17.1 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EKX46962.1 - 3.7e-05 23.8 0.4 0.024 15.2 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat W2 PF02020.18 EKX46963.1 - 3.5e-11 43.1 2.7 5.2e-11 42.5 2.7 1.2 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Herpes_UL55 PF04537.12 EKX46963.1 - 0.053 13.5 0.0 0.065 13.2 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL55 protein WD40 PF00400.32 EKX46964.1 - 1.1e-41 140.0 59.9 0.00018 22.3 0.1 21.3 24 0 0 24 24 24 11 WD domain, G-beta repeat HELP PF03451.14 EKX46964.1 - 1.6e-23 82.3 0.3 2.3e-10 40.2 0.0 2.7 2 0 0 2 2 2 2 HELP motif ANAPC4_WD40 PF12894.7 EKX46964.1 - 1.7e-14 53.9 0.0 0.091 13.1 0.0 10.5 11 2 1 12 12 12 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EKX46964.1 - 0.023 14.1 0.1 9.2 5.5 0.0 3.9 3 0 0 3 3 3 0 WD40-like domain RAB3GAP2_N PF14655.6 EKX46964.1 - 0.052 12.8 0.0 0.21 10.8 0.0 2.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2937 PF11157.8 EKX46964.1 - 0.18 11.5 0.0 0.42 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) DEAD PF00270.29 EKX46965.1 - 6.7e-45 153.0 0.0 1.1e-44 152.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX46965.1 - 2.5e-26 92.2 0.0 1.5e-25 89.7 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GUCT PF08152.12 EKX46965.1 - 6.1e-05 23.2 0.0 0.00026 21.2 0.0 2.0 2 0 0 2 2 2 1 GUCT (NUC152) domain CMS1 PF14617.6 EKX46965.1 - 8.3e-05 22.0 0.0 0.00021 20.8 0.0 1.6 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 EKX46965.1 - 0.044 13.8 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EKX46965.1 - 0.072 12.8 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain CtaG_Cox11 PF04442.14 EKX46966.1 - 2.1e-60 203.1 0.4 2.5e-60 202.9 0.4 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 C2 PF00168.30 EKX46968.1 - 2.2e-27 95.3 0.8 2.6e-15 56.6 0.1 2.6 2 1 0 2 2 2 2 C2 domain DUF4121 PF13497.6 EKX46969.1 - 0.23 10.6 0.0 0.29 10.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) Pkinase_Tyr PF07714.17 EKX46970.1 - 2.5e-41 141.7 0.0 3e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX46970.1 - 2.3e-37 128.8 0.0 2.7e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EKX46970.1 - 0.057 13.3 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EKX46970.1 - 0.14 11.2 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 EKX46970.1 - 0.25 10.1 0.0 0.34 9.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase LSM PF01423.22 EKX46971.1 - 1.5e-19 69.4 0.4 2e-19 69.1 0.4 1.1 1 0 0 1 1 1 1 LSM domain Ephrin_rec_like PF07699.13 EKX46972.1 - 0.0001 22.0 56.9 0.0096 15.7 7.3 8.3 3 3 5 8 8 8 6 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX46972.1 - 0.053 13.9 3.0 0.053 13.9 3.0 8.0 7 2 1 8 8 8 0 TNFR/NGFR cysteine-rich region Ephrin_rec_like PF07699.13 EKX46973.1 - 3.1e-10 39.7 66.6 0.002 17.8 9.1 6.6 4 3 2 6 6 6 4 Putative ephrin-receptor like SBBP PF06739.11 EKX46973.1 - 0.018 15.0 0.0 0.05 13.6 0.0 1.8 2 0 0 2 2 2 0 Beta-propeller repeat TNFR_c6 PF00020.18 EKX46973.1 - 0.028 14.8 2.2 0.028 14.8 2.2 7.7 4 2 3 7 7 7 0 TNFR/NGFR cysteine-rich region SBBP PF06739.11 EKX46974.1 - 3.1e-18 65.5 30.2 0.75 9.8 0.0 13.5 13 0 0 13 13 13 5 Beta-propeller repeat Ephrin_rec_like PF07699.13 EKX46974.1 - 5.2e-07 29.3 470.5 0.0049 16.6 7.5 36.6 28 7 8 36 36 36 25 Putative ephrin-receptor like DNase_NucA_NucB PF14040.6 EKX46974.1 - 0.00012 22.4 3.5 1e+02 3.3 0.0 5.9 5 0 0 5 5 5 0 Deoxyribonuclease NucA/NucB TNFR_c6 PF00020.18 EKX46975.1 - 1.4 9.4 13.8 0.78 10.2 0.7 3.8 3 2 0 3 3 3 0 TNFR/NGFR cysteine-rich region Dickkopf_N PF04706.12 EKX46975.1 - 1.8 9.1 13.0 12 6.5 0.3 4.7 2 2 2 4 4 4 0 Dickkopf N-terminal cysteine-rich region Ephrin_rec_like PF07699.13 EKX46977.1 - 3.3e-16 58.8 77.5 0.00026 20.7 1.3 8.2 5 2 3 8 8 8 8 Putative ephrin-receptor like NCD3G PF07562.14 EKX46977.1 - 2.4e-12 46.6 59.9 0.069 13.1 2.8 8.9 7 3 0 8 8 8 8 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX46977.1 - 2.2e-07 31.2 69.9 0.015 15.6 3.0 10.0 7 4 2 9 9 9 8 TNFR/NGFR cysteine-rich region Sgf11 PF08209.11 EKX46979.1 - 9.3e-11 41.1 1.5 1.9e-10 40.1 1.5 1.5 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) DUF1287 PF06940.11 EKX46980.1 - 0.041 13.5 0.4 2.2 7.9 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1287) Cupin_4 PF08007.12 EKX46980.1 - 0.042 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Cupin superfamily protein WD40 PF00400.32 EKX46981.1 - 7.3e-14 52.0 4.1 0.00012 22.8 0.2 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX46981.1 - 5.4e-08 33.0 0.0 0.26 11.6 0.0 3.3 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Vps16_N PF04841.13 EKX46981.1 - 0.0011 17.8 0.0 0.0015 17.4 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region PQQ_3 PF13570.6 EKX46981.1 - 0.0019 18.6 8.1 0.85 10.2 0.0 4.6 5 0 0 5 5 5 1 PQQ-like domain Ge1_WD40 PF16529.5 EKX46981.1 - 0.012 14.6 0.0 0.041 12.8 0.0 1.8 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EKX46981.1 - 0.047 12.3 0.0 0.27 9.9 0.0 1.9 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EKX46981.1 - 0.17 10.6 0.0 6 5.5 0.0 2.1 1 1 0 2 2 2 0 Nup133 N terminal like EF-hand_7 PF13499.6 EKX46982.1 - 6.6e-15 55.3 0.6 4.4e-10 39.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX46982.1 - 2.3e-12 45.8 5.9 1.5e-06 27.7 1.1 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EKX46982.1 - 4.4e-12 44.6 8.2 2.1e-08 33.1 0.9 3.7 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 EKX46982.1 - 2.6e-07 29.8 3.1 0.015 14.7 0.4 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EKX46982.1 - 0.00039 20.2 4.7 0.071 13.0 0.3 3.8 2 1 2 4 4 4 2 EF-hand domain pair Caleosin PF05042.13 EKX46982.1 - 0.0072 16.3 0.0 0.015 15.2 0.0 1.5 2 0 0 2 2 2 1 Caleosin related protein EF-hand_9 PF14658.6 EKX46982.1 - 0.04 14.2 0.0 0.071 13.5 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain EF-hand_14 PF17959.1 EKX46982.1 - 0.12 12.7 0.2 0.61 10.5 0.1 1.9 2 0 0 2 2 2 0 EF-hand domain EF-hand_10 PF14788.6 EKX46982.1 - 0.17 11.8 1.1 0.63 10.0 0.1 2.5 2 1 1 3 3 3 0 EF hand DUF4294 PF14127.6 EKX46983.1 - 0.0083 16.0 4.6 0.019 14.9 4.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4294) DUF4407 PF14362.6 EKX46983.1 - 1.6 8.0 9.7 1.8 7.9 8.5 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Cas_Cas6 PF01881.16 EKX46983.1 - 5.5 7.5 7.7 1.1 9.8 1.6 2.2 1 1 1 2 2 2 0 CRISPR associated protein Cas6 Ephrin_rec_like PF07699.13 EKX46985.1 - 3.3e-22 78.0 41.1 1.8e-07 30.8 4.7 5.6 1 1 4 5 5 5 5 Putative ephrin-receptor like NCD3G PF07562.14 EKX46985.1 - 8.1e-09 35.3 37.6 0.014 15.3 4.3 5.8 2 1 5 7 7 7 7 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX46985.1 - 1.9e-06 28.1 33.0 0.02 15.3 0.7 7.2 2 2 5 7 7 7 5 TNFR/NGFR cysteine-rich region zf-C3HC4_4 PF15227.6 EKX46985.1 - 0.074 13.2 1.0 0.074 13.2 1.0 4.9 3 1 3 6 6 6 0 zinc finger of C3HC4-type, RING Prim_Zn_Ribbon PF08273.12 EKX46985.1 - 0.17 12.2 0.8 0.17 12.2 0.8 6.0 2 2 3 5 5 5 0 Zinc-binding domain of primase-helicase DUF3597 PF12200.8 EKX46986.1 - 0.1 13.1 22.0 3 8.4 1.8 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3597) DUF2052 PF09747.9 EKX46986.1 - 1.1 9.3 4.5 0.83 9.8 2.9 1.6 1 1 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Mito_carr PF00153.27 EKX46987.1 - 3.4e-38 129.4 2.3 3.5e-15 55.7 0.1 4.0 2 2 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EKX46987.1 - 0.064 12.4 0.1 0.78 8.8 0.0 2.2 2 0 0 2 2 2 0 Gammaproteobacterial serine protease Ribosomal_L28 PF00830.19 EKX46988.1 - 6.3e-16 58.3 4.3 1.1e-15 57.6 4.3 1.4 1 0 0 1 1 1 1 Ribosomal L28 family ETF_QO PF05187.13 EKX46989.1 - 2.4e-38 130.4 0.3 4.5e-38 129.6 0.3 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 EKX46989.1 - 1e-10 41.8 0.2 2e-05 24.4 0.6 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EKX46989.1 - 8.7e-09 35.0 0.3 0.00012 21.3 1.3 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 EKX46989.1 - 1.4e-06 27.8 0.0 5.1e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 EKX46989.1 - 8.3e-06 25.9 0.1 2.8e-05 24.3 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EKX46989.1 - 1.3e-05 25.7 0.3 0.12 13.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EKX46989.1 - 1.9e-05 24.1 0.0 6.1e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EKX46989.1 - 4.8e-05 22.6 0.1 8.6e-05 21.8 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 EKX46989.1 - 8.7e-05 21.4 0.3 0.00015 20.6 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EKX46989.1 - 0.00029 20.2 0.3 0.00047 19.5 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EKX46989.1 - 0.00069 19.0 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 EKX46989.1 - 0.0024 17.9 0.0 0.0062 16.5 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 EKX46989.1 - 0.025 13.7 0.0 0.049 12.8 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Fer4_7 PF12838.7 EKX46989.1 - 0.033 14.8 1.8 0.083 13.5 1.8 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain GIDA PF01134.22 EKX46989.1 - 0.13 11.3 0.4 0.19 10.8 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 EKX46989.1 - 0.14 11.5 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase PMSR PF01625.21 EKX46990.1 - 8.7e-06 26.0 0.0 1.6e-05 25.1 0.0 1.4 1 1 0 1 1 1 1 Peptide methionine sulfoxide reductase Methyltransf_25 PF13649.6 EKX46991.1 - 1.7e-06 28.7 1.2 8.3e-06 26.4 0.1 2.9 3 0 0 3 3 2 1 Methyltransferase domain MTS PF05175.14 EKX46991.1 - 1.5e-05 24.6 0.1 4.8e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EKX46991.1 - 1.9e-05 24.6 0.0 8.4e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX46991.1 - 2.7e-05 24.8 0.0 8e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EKX46991.1 - 2.9e-05 23.5 0.0 6.3e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 EKX46991.1 - 0.0016 18.2 0.0 0.43 10.3 0.0 2.4 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_4 PF02390.17 EKX46991.1 - 0.0031 17.0 0.0 0.0086 15.6 0.0 1.8 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.12 EKX46991.1 - 0.0045 17.6 0.0 0.013 16.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX46991.1 - 0.0055 16.5 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EKX46991.1 - 0.017 14.6 0.0 0.038 13.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 EKX46991.1 - 0.02 14.9 0.0 0.069 13.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Sulfotransfer_4 PF17784.1 EKX46991.1 - 0.024 14.5 0.1 0.87 9.4 0.0 2.5 2 0 0 2 2 2 0 Sulfotransferase domain PCMT PF01135.19 EKX46991.1 - 0.037 13.8 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TPR_3 PF07720.12 EKX46991.1 - 0.043 13.8 0.0 0.69 10.0 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltransf_32 PF13679.6 EKX46991.1 - 0.065 13.2 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain TPR_14 PF13428.6 EKX46991.1 - 0.067 14.1 0.2 0.89 10.5 0.0 3.1 3 0 0 3 3 1 0 Tetratricopeptide repeat DOT1 PF08123.13 EKX46991.1 - 0.18 11.3 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltrans_RNA PF04452.14 EKX46992.1 - 2.3e-46 158.0 0.0 5.3e-45 153.5 0.0 2.0 1 1 0 1 1 1 1 RNA methyltransferase MitoNEET_N PF10660.9 EKX46993.1 - 0.14 12.2 0.2 0.2 11.7 0.2 1.3 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus Pkinase PF00069.25 EKX46994.1 - 3.9e-71 239.5 0.0 5.3e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX46994.1 - 8.4e-37 126.9 0.0 1.4e-36 126.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 EKX46994.1 - 2.6e-14 53.0 0.3 4.2e-13 49.2 0.3 2.4 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain Kinase-like PF14531.6 EKX46994.1 - 8.9e-07 28.5 0.0 1.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EKX46994.1 - 0.057 12.8 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ccdc124 PF06244.12 EKX46995.1 - 4.2e-33 114.7 24.2 7.5e-32 110.6 24.2 2.1 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 DUF5587 PF17825.1 EKX46995.1 - 0.0026 15.2 0.8 0.0028 15.1 0.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5587) HMG_box PF00505.19 EKX46995.1 - 0.0047 17.3 0.4 0.0047 17.3 0.4 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box Med8 PF10232.9 EKX46995.1 - 0.061 12.9 10.6 0.011 15.3 5.0 2.0 1 1 1 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 YABBY PF04690.13 EKX46995.1 - 1.2 9.7 13.7 0.06 13.9 4.0 2.0 1 1 1 2 2 2 0 YABBY protein AAR2 PF05282.11 EKX46995.1 - 3.4 7.0 8.3 2.6 7.4 7.0 1.4 1 1 0 1 1 1 0 AAR2 protein Pkinase PF00069.25 EKX46996.1 - 5.9e-70 235.7 0.0 6.6e-70 235.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX46996.1 - 1.6e-34 119.4 0.0 1.8e-34 119.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX46996.1 - 5.2e-05 22.7 0.0 0.0052 16.1 0.0 2.4 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 EKX46996.1 - 0.083 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EKX46997.1 - 4.2e-26 91.9 1.2 4.6e-26 91.8 1.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX46997.1 - 3.6e-15 55.9 1.3 4.2e-15 55.7 1.3 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EKX46997.1 - 8e-05 22.3 0.2 0.00011 21.9 0.2 1.2 1 0 0 1 1 1 1 RIO1 family MukB_hinge PF16330.5 EKX46997.1 - 0.02 14.6 0.1 0.024 14.3 0.1 1.1 1 0 0 1 1 1 0 MukB hinge domain DUF3805 PF12712.7 EKX46997.1 - 0.048 13.8 0.0 0.058 13.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3805) Kdo PF06293.14 EKX46997.1 - 0.18 11.1 1.2 0.49 9.7 0.4 1.8 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family HSCB_C PF07743.13 EKX46999.1 - 8.7e-09 35.8 0.2 8.7e-09 35.8 0.2 2.1 3 0 0 3 3 3 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 EKX46999.1 - 2.4e-06 27.6 0.1 5.3e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain HscB_4_cys PF18256.1 EKX46999.1 - 0.0032 17.2 8.9 0.0032 17.2 8.9 2.3 2 0 0 2 2 2 1 Co-chaperone HscB tetracysteine metal binding motif DUF3222 PF11519.8 EKX46999.1 - 0.048 13.9 0.3 0.31 11.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3222) Ax_dynein_light PF10211.9 EKX46999.1 - 0.092 12.7 1.4 0.11 12.4 0.1 1.8 2 0 0 2 2 2 0 Axonemal dynein light chain IQ PF00612.27 EKX47000.1 - 7.9e-13 47.0 26.5 0.0021 17.7 1.0 6.0 5 0 0 5 5 5 4 IQ calmodulin-binding motif UDPGP PF01704.18 EKX47001.1 - 4.4e-50 170.5 0.0 5.6e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 EKX47001.1 - 0.0054 17.1 0.6 0.026 14.9 0.1 2.4 2 1 0 2 2 2 1 MobA-like NTP transferase domain CGI-121 PF08617.10 EKX47001.1 - 0.059 13.5 0.1 0.095 12.8 0.1 1.2 1 0 0 1 1 1 0 Kinase binding protein CGI-121 SR-25 PF10500.9 EKX47002.1 - 0.071 12.7 32.9 0.11 12.0 32.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HA2 PF04408.23 EKX47002.1 - 0.88 9.9 5.4 1.9 8.8 5.4 1.6 1 0 0 1 1 1 0 Helicase associated domain (HA2) AP3D1 PF06375.11 EKX47002.1 - 1.5 9.0 25.8 3 8.1 25.8 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 EIIBC-GUT_N PF03612.14 EKX47002.1 - 2.1 8.1 8.7 3.3 7.4 8.7 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus EOS1 PF12326.8 EKX47002.1 - 4.7 7.1 6.4 7.3 6.5 6.4 1.3 1 0 0 1 1 1 0 N-glycosylation protein DUF3807 PF12720.7 EKX47002.1 - 4.9 7.4 18.5 7.2 6.8 18.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) RNA_pol_Rpc4 PF05132.14 EKX47002.1 - 8.4 6.8 14.7 16 5.9 14.7 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 CbiA PF01656.23 EKX47003.1 - 7.8e-05 22.7 0.4 0.00029 20.9 0.4 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EKX47003.1 - 0.00023 21.1 0.0 0.00091 19.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 EKX47003.1 - 0.013 14.8 0.3 0.49 9.6 0.0 2.5 2 1 1 3 3 3 0 ATPase MipZ ResIII PF04851.15 EKX47003.1 - 0.018 15.0 0.0 0.078 13.0 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EKX47003.1 - 0.086 13.2 0.1 0.3 11.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain VirC1 PF07015.11 EKX47003.1 - 0.13 11.5 0.0 0.32 10.2 0.0 1.6 2 0 0 2 2 2 0 VirC1 protein TNFR_c6 PF00020.18 EKX47004.1 - 5.7e-19 68.2 67.9 8e-06 26.2 11.0 7.0 2 1 5 7 7 7 6 TNFR/NGFR cysteine-rich region Nup88 PF10168.9 EKX47004.1 - 0.051 11.4 0.1 0.072 10.9 0.1 1.1 1 0 0 1 1 1 0 Nuclear pore component MtrG PF04210.13 EKX47004.1 - 0.21 11.5 0.3 0.37 10.7 0.3 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G TPR_1 PF00515.28 EKX47004.1 - 0.24 11.3 0.4 0.78 9.7 0.4 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat YkyA PF10368.9 EKX47004.1 - 0.39 10.3 1.8 0.58 9.8 1.8 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF3552 PF12072.8 EKX47004.1 - 0.74 9.2 2.8 1.9 7.9 1.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) TPR_2 PF07719.17 EKX47004.1 - 2.7 8.3 4.9 0.57 10.4 0.4 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat SR-25 PF10500.9 EKX47004.1 - 5 6.7 10.9 12 5.4 10.9 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Aa_trans PF01490.18 EKX47005.1 - 4e-38 131.2 12.6 4.2e-23 81.7 1.5 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein UBA_4 PF14555.6 EKX47006.1 - 7.3e-05 22.5 0.6 0.00017 21.3 0.2 1.9 2 0 0 2 2 2 1 UBA-like domain TAP_C PF03943.13 EKX47006.1 - 0.00029 20.4 2.0 0.00067 19.2 2.0 1.6 1 0 0 1 1 1 1 TAP C-terminal domain NTF2 PF02136.20 EKX47006.1 - 0.017 15.7 2.1 0.42 11.2 0.7 2.9 2 1 0 2 2 2 0 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 EKX47007.1 - 2.9e-15 55.8 0.1 6.4e-15 54.7 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3225 PF11533.8 EKX47007.1 - 0.12 12.1 0.9 0.26 11.0 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3225) Hydrolase_4 PF12146.8 EKX47008.1 - 4.8e-05 22.7 0.2 0.013 14.8 0.1 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DUF1057 PF06342.12 EKX47008.1 - 0.00046 19.3 0.0 0.00064 18.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_6 PF12697.7 EKX47008.1 - 0.0016 19.1 1.3 0.0026 18.4 1.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EKX47008.1 - 0.018 14.7 0.2 0.19 11.3 0.2 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EKX47008.1 - 0.025 14.4 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold GSu_C4xC__C2xCH PF09698.10 EKX47008.1 - 0.039 14.7 0.2 0.096 13.5 0.2 1.7 1 0 0 1 1 1 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) Ank_2 PF12796.7 EKX47009.1 - 2.2e-15 57.0 0.1 3.3e-09 37.2 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX47009.1 - 8.3e-15 54.7 1.6 5.1e-06 26.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX47009.1 - 9.8e-14 50.1 0.1 0.0051 17.2 0.0 5.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EKX47009.1 - 1.7e-13 50.8 0.2 6.8e-06 26.5 0.0 3.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX47009.1 - 5.6e-12 45.5 0.6 0.058 13.9 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat CALM_bind PF16025.5 EKX47009.1 - 0.023 15.1 0.2 0.023 15.1 0.2 4.2 4 1 0 4 4 4 0 Calcium-dependent calmodulin binding PDZ PF00595.24 EKX47009.1 - 0.075 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 PDZ domain TFIIA PF03153.13 EKX47009.1 - 3 7.8 17.4 6.1 6.7 17.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HEM4 PF02602.15 EKX47010.1 - 2.4e-45 154.7 0.1 3.1e-45 154.4 0.1 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD PX PF00787.24 EKX47011.1 - 3.7e-07 30.1 0.2 1e-06 28.7 0.2 1.7 1 0 0 1 1 1 1 PX domain 2OG-FeII_Oxy_2 PF13532.6 EKX47012.1 - 3.5e-37 128.5 0.0 1.6e-36 126.3 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily IMS_C PF11799.8 EKX47012.1 - 0.16 12.6 0.0 0.31 11.7 0.0 1.5 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain Prenylcys_lyase PF07156.14 EKX47013.1 - 4.7e-67 226.6 0.0 1.7e-35 122.8 0.0 2.2 2 0 0 2 2 2 2 Prenylcysteine lyase Amino_oxidase PF01593.24 EKX47013.1 - 1.9e-16 60.4 0.1 2.8e-16 59.9 0.1 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EKX47013.1 - 1.5e-06 28.3 0.0 4.3e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF2529 PF10740.9 EKX47013.1 - 0.078 12.6 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2529) DnaJ PF00226.31 EKX47014.1 - 2.5e-14 53.1 0.0 2.7e-14 53.0 0.0 1.0 1 0 0 1 1 1 1 DnaJ domain GAF PF01590.26 EKX47017.1 - 4.8e-09 36.9 0.1 0.0073 16.9 0.0 4.1 4 0 0 4 4 4 3 GAF domain GAF_2 PF13185.6 EKX47017.1 - 1.1e-07 32.3 0.0 0.0087 16.4 0.0 3.7 3 0 0 3 3 3 3 GAF domain KAR PF15222.6 EKX47017.1 - 0.012 15.9 0.0 0.074 13.4 0.0 2.1 2 0 0 2 2 2 0 Kidney androgen-regulated C2 PF00168.30 EKX47018.1 - 5.2e-09 36.3 0.0 1.1e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain SID-1_RNA_chan PF13965.6 EKX47018.1 - 0.0064 15.0 1.6 0.0092 14.4 1.6 1.3 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Pex14_N PF04695.13 EKX47018.1 - 0.012 16.3 29.8 0.012 16.3 29.8 3.6 3 1 0 3 3 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RR_TM4-6 PF06459.12 EKX47018.1 - 0.015 15.1 21.9 0.041 13.7 21.9 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.8 EKX47018.1 - 0.019 13.8 15.9 0.039 12.7 15.9 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2828 PF11443.8 EKX47018.1 - 0.039 12.0 20.7 0.024 12.8 18.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) DUF2201_N PF13203.6 EKX47018.1 - 0.076 12.6 14.6 0.13 11.8 14.6 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain TERB2 PF15101.6 EKX47018.1 - 0.26 11.3 30.6 0.59 10.2 30.6 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Paf1 PF03985.13 EKX47018.1 - 0.37 9.7 25.5 0.89 8.5 25.5 1.6 1 0 0 1 1 1 0 Paf1 Presenilin PF01080.17 EKX47018.1 - 0.39 9.4 27.7 0.97 8.1 27.7 1.6 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 EKX47018.1 - 0.4 10.9 16.8 1.9 8.6 16.8 2.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Endostatin PF06482.11 EKX47018.1 - 0.42 10.0 20.9 1.2 8.5 20.9 1.7 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Med19 PF10278.9 EKX47018.1 - 0.42 10.5 12.1 0.87 9.5 12.1 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 SpoIIP PF07454.11 EKX47018.1 - 0.63 9.4 24.4 1.3 8.4 24.4 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) LMBR1 PF04791.16 EKX47018.1 - 0.7 8.7 7.4 1.4 7.7 7.4 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1980 PF09323.10 EKX47018.1 - 0.97 9.3 17.3 3 7.7 17.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Hid1 PF12722.7 EKX47018.1 - 1.1 7.3 23.4 2.2 6.3 23.4 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4637 PF15470.6 EKX47018.1 - 1.8 8.3 13.7 3.5 7.3 13.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CLN3 PF02487.17 EKX47018.1 - 2 7.4 17.5 4.1 6.4 17.5 1.4 1 0 0 1 1 1 0 CLN3 protein AAA_23 PF13476.6 EKX47018.1 - 2.3 8.7 27.7 0.89 10.0 23.7 2.2 2 0 0 2 2 2 0 AAA domain Vfa1 PF08432.10 EKX47018.1 - 3 8.1 28.5 0.5 10.7 23.0 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 CobT PF06213.12 EKX47018.1 - 3.1 7.1 36.8 6.4 6.1 36.8 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF913 PF06025.12 EKX47018.1 - 3.4 6.6 16.4 8 5.3 16.4 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Borrelia_P83 PF05262.11 EKX47018.1 - 3.7 5.9 23.2 6 5.2 23.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4746 PF15928.5 EKX47018.1 - 4.6 6.6 19.9 1.4 8.3 16.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Paramyxo_ncap PF00973.19 EKX47018.1 - 5.6 5.8 15.7 7.9 5.3 15.7 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Peptidase_S49_N PF08496.10 EKX47018.1 - 5.7 7.0 18.4 15 5.7 18.4 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CCDC53 PF10152.9 EKX47018.1 - 5.9 7.3 35.6 0.43 11.0 23.9 3.3 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex CDC45 PF02724.14 EKX47018.1 - 6 5.0 23.5 2.3 6.4 21.1 1.4 2 0 0 2 2 2 0 CDC45-like protein DUF2126 PF09899.9 EKX47018.1 - 7.9 4.4 17.3 12 3.8 17.3 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Rtf2 PF04641.12 EKX47018.1 - 9.7 5.5 21.9 22 4.3 21.9 1.6 1 0 0 1 1 1 0 Rtf2 RING-finger Glycolytic PF00274.19 EKX47019.1 - 1.1e-165 550.6 0.0 1.2e-165 550.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Asparaginase_2 PF01112.18 EKX47020.1 - 2.4e-74 250.1 1.5 3e-74 249.8 1.5 1.0 1 0 0 1 1 1 1 Asparaginase ABA_WDS PF02496.16 EKX47020.1 - 0.45 11.0 2.7 0.45 11.0 1.2 1.8 1 1 0 1 1 1 0 ABA/WDS induced protein tRNA-synt_1b PF00579.25 EKX47021.1 - 3.9e-22 78.9 0.0 7e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) CpeS PF09367.10 EKX47022.1 - 2.1e-53 180.7 1.2 2.2e-53 180.7 0.5 1.3 2 0 0 2 2 2 1 CpeS-like protein Pkinase PF00069.25 EKX47023.1 - 1.5e-61 208.1 0.0 1.7e-61 207.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX47023.1 - 6.5e-41 140.3 0.0 7.6e-41 140.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX47023.1 - 1.2e-05 24.8 0.0 2e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EKX47023.1 - 0.00011 22.3 0.0 0.00045 20.2 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EKX47023.1 - 0.00072 18.7 0.1 0.0015 17.7 0.1 1.4 1 1 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 EKX47023.1 - 0.0016 17.3 0.0 0.0034 16.2 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EKX47023.1 - 0.013 14.5 0.2 0.017 14.1 0.2 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 EKX47023.1 - 0.042 12.8 0.9 1.8 7.4 0.1 2.2 1 1 0 2 2 2 0 Poxvirus serine/threonine protein kinase SNARE_assoc PF09335.11 EKX47024.1 - 3e-16 60.0 4.5 7.7e-16 58.7 4.5 1.6 1 1 0 1 1 1 1 SNARE associated Golgi protein DAHP_synth_1 PF00793.20 EKX47025.1 - 1.2e-105 352.4 0.0 1.4e-105 352.2 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family PP2C PF00481.21 EKX47026.1 - 8.6e-40 137.0 0.0 9.6e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C DUF4488 PF14869.6 EKX47026.1 - 0.026 14.4 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4488) SpoIIE PF07228.12 EKX47026.1 - 0.031 14.2 0.1 0.036 14.0 0.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) ATP-synt_G PF04718.15 EKX47027.1 - 8e-09 36.2 0.0 9.6e-09 36.0 0.0 1.2 1 1 0 1 1 1 1 Mitochondrial ATP synthase g subunit HSP70 PF00012.20 EKX47028.1 - 2.3e-76 257.3 33.8 1.6e-44 152.2 0.0 5.4 2 1 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 EKX47028.1 - 0.0014 17.5 0.1 0.0014 17.5 0.1 1.7 2 0 0 2 2 2 1 MreB/Mbl protein NAD_binding_10 PF13460.6 EKX47028.1 - 0.081 12.8 1.5 0.15 11.9 0.3 2.0 2 0 0 2 2 2 0 NAD(P)H-binding DUF4665 PF15679.5 EKX47028.1 - 0.1 13.2 5.8 1.8 9.3 1.4 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4665) Amidase02_C PF12123.8 EKX47028.1 - 3.9 7.3 4.5 0.85 9.4 0.4 1.9 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase Sec34 PF04136.15 EKX47028.1 - 5.1 7.0 6.4 4.8 7.0 0.6 2.6 3 0 0 3 3 3 0 Sec34-like family Bestrophin PF01062.21 EKX47030.1 - 9.9e-27 94.1 0.6 1.2e-26 93.8 0.6 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel ExoD PF06055.12 EKX47030.1 - 0.068 12.6 1.4 0.097 12.0 1.4 1.2 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD OHCU_decarbox PF09349.10 EKX47030.1 - 0.12 12.8 0.1 0.2 12.1 0.1 1.3 1 0 0 1 1 1 0 OHCU decarboxylase HBB PF06777.11 EKX47030.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Helical and beta-bridge domain DUF2568 PF10823.8 EKX47030.1 - 0.18 12.1 3.3 0.23 11.8 0.3 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2568) ATG16 PF08614.11 EKX47031.1 - 0.022 15.0 0.2 0.043 14.0 0.2 1.6 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Phage_hub_GP28 PF11110.8 EKX47031.1 - 0.19 11.6 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Baseplate hub distal subunit cNMP_binding PF00027.29 EKX47032.1 - 1.6e-26 92.2 0.1 6.7e-12 45.3 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Agenet PF05641.12 EKX47033.1 - 3.7e-06 27.3 1.6 1.1e-05 25.9 1.6 1.8 1 0 0 1 1 1 1 Agenet domain Myb_DNA-binding PF00249.31 EKX47033.1 - 5.4e-06 26.5 0.0 1.4e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Tudor-knot PF11717.8 EKX47033.1 - 0.0038 17.1 0.2 0.0087 15.9 0.2 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Tudor_4 PF18358.1 EKX47033.1 - 0.13 11.8 4.4 0.13 11.9 2.4 2.0 1 1 1 2 2 2 0 Histone methyltransferase Tudor domain UDPG_MGDP_dh_N PF03721.14 EKX47034.1 - 3.9e-59 199.4 0.0 6.7e-59 198.6 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 EKX47034.1 - 2.3e-31 107.8 0.0 4.6e-31 106.9 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 EKX47034.1 - 9.7e-22 77.4 0.1 2.3e-14 53.7 0.0 3.3 2 1 1 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 3HCDH_N PF02737.18 EKX47034.1 - 0.0033 17.3 0.0 0.0081 16.1 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EKX47034.1 - 0.0043 17.2 0.0 0.016 15.4 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.6 EKX47034.1 - 0.034 14.6 0.0 10 6.6 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 EKX47034.1 - 0.073 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 EKX47034.1 - 0.076 13.3 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 EKX47034.1 - 0.083 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus CBFD_NFYB_HMF PF00808.23 EKX47036.1 - 3.5e-10 40.0 1.2 3.5e-10 40.0 1.2 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EKX47036.1 - 6.4e-05 23.3 0.6 6.4e-05 23.3 0.6 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Spt20 PF12090.8 EKX47036.1 - 6.6e-05 22.6 1.2 8e-05 22.4 1.2 1.0 1 0 0 1 1 1 1 Spt20 family TAFII28 PF04719.14 EKX47036.1 - 0.009 16.1 0.2 0.015 15.4 0.2 1.3 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Bromo_TP PF07524.13 EKX47036.1 - 0.023 14.7 0.1 0.11 12.6 0.0 1.9 1 1 1 2 2 2 0 Bromodomain associated PqqD PF05402.12 EKX47036.1 - 0.051 13.9 0.8 2.1 8.7 0.2 2.3 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) TAF PF02969.17 EKX47036.1 - 0.13 12.5 0.6 1.6 8.9 0.1 2.3 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) WD40 PF00400.32 EKX47037.1 - 3e-19 69.0 22.0 0.0078 17.0 0.3 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX47037.1 - 7.1e-09 35.9 5.3 0.0095 16.2 0.3 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX47037.1 - 0.0088 15.0 2.0 12 4.7 0.0 3.8 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein UCH PF00443.29 EKX47038.1 - 3.4e-65 220.1 0.0 4.9e-65 219.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EKX47038.1 - 2.3e-13 50.5 0.7 2.9e-09 37.0 0.0 3.2 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EKX47038.1 - 9.9e-05 22.9 1.4 0.00053 20.6 0.5 2.4 2 0 0 2 2 2 1 DUSP domain MSP1_C PF07462.11 EKX47038.1 - 0.017 13.8 0.5 0.028 13.1 0.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF3311 PF11755.8 EKX47038.1 - 1.6 8.7 4.0 0.4 10.7 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) COX14 PF14880.6 EKX47039.1 - 6.4e-10 38.7 0.1 7.7e-10 38.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c assembly LEA_4 PF02987.16 EKX47039.1 - 0.025 14.7 0.1 0.034 14.2 0.1 1.1 1 0 0 1 1 1 0 Late embryogenesis abundant protein bZIP_1 PF00170.21 EKX47040.1 - 0.0034 17.5 4.2 0.0034 17.5 4.2 2.3 1 1 1 2 2 2 1 bZIP transcription factor zf-C4H2 PF10146.9 EKX47040.1 - 0.13 12.6 10.9 0.14 12.5 10.9 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein Atg14 PF10186.9 EKX47040.1 - 0.34 10.0 9.6 0.41 9.7 9.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phlebovirus_NSM PF07246.11 EKX47040.1 - 0.62 9.4 6.8 0.74 9.1 6.8 1.0 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M FAM76 PF16046.5 EKX47040.1 - 1 8.6 9.1 1.3 8.3 9.1 1.2 1 0 0 1 1 1 0 FAM76 protein UPF0242 PF06785.11 EKX47040.1 - 1.6 8.8 14.6 2.7 8.0 14.6 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 EKX47040.1 - 4.7 7.9 12.8 4.1 8.1 7.9 2.1 1 1 1 2 2 2 0 Initiation control protein YabA PspA_IM30 PF04012.12 EKX47041.1 - 0.13 11.8 5.5 0.14 11.7 4.0 1.7 1 1 1 2 2 2 0 PspA/IM30 family TBCA PF02970.16 EKX47041.1 - 0.19 12.1 5.0 0.38 11.1 5.0 1.5 1 0 0 1 1 1 0 Tubulin binding cofactor A UPF0242 PF06785.11 EKX47041.1 - 0.53 10.3 4.3 0.33 11.0 2.5 1.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TBCC PF07986.12 EKX47042.1 - 6.7e-06 25.8 1.4 1.2e-05 25.1 1.4 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 EKX47042.1 - 0.00024 20.8 3.0 0.00039 20.1 3.0 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal DCP1 PF06058.13 EKX47043.1 - 8.6e-26 90.2 0.0 9.7e-26 90.0 0.0 1.0 1 0 0 1 1 1 1 Dcp1-like decapping family WASH_WAHD PF11945.8 EKX47044.1 - 1.9e-18 67.0 0.0 2.8e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 WAHD domain of WASH complex Amino_oxidase PF01593.24 EKX47045.1 - 6.1e-91 306.0 0.0 8.2e-91 305.5 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EKX47045.1 - 1.5e-13 50.7 1.6 2.3e-13 50.2 0.7 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EKX47045.1 - 1.1e-11 44.5 0.1 5.9e-07 29.0 0.1 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EKX47045.1 - 3.5e-08 33.9 0.9 3.8e-06 27.4 0.2 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EKX47045.1 - 8.5e-07 28.4 0.8 0.0012 18.0 0.5 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_2 PF00890.24 EKX47045.1 - 6.5e-06 25.5 0.4 1.1e-05 24.7 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EKX47045.1 - 2.9e-05 23.0 0.4 0.00023 20.0 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 EKX47045.1 - 4.3e-05 23.3 3.7 0.00014 21.6 3.7 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EKX47045.1 - 0.0001 21.6 0.1 0.00021 20.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 EKX47045.1 - 0.00019 21.4 1.8 0.12 12.3 0.2 2.6 2 1 0 2 2 2 2 FAD-NAD(P)-binding FAD_oxidored PF12831.7 EKX47045.1 - 0.00026 20.5 0.1 0.00039 19.9 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EKX47045.1 - 0.00031 20.1 1.6 0.00089 18.6 0.6 2.0 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 EKX47045.1 - 0.00074 18.9 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EKX47045.1 - 0.0008 18.6 1.4 0.002 17.3 0.5 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EKX47045.1 - 0.015 14.6 0.7 0.061 12.6 0.7 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TOBE PF03459.17 EKX47045.1 - 0.16 12.3 0.0 5 7.5 0.0 2.5 2 0 0 2 2 2 0 TOBE domain Ammonium_transp PF00909.21 EKX47046.1 - 1.3e-51 175.6 17.6 1.7e-51 175.2 17.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Ammonium_transp PF00909.21 EKX47047.1 - 5.1e-22 78.1 7.9 6.4e-22 77.8 7.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Pkinase PF00069.25 EKX47048.1 - 9.7e-68 228.4 0.0 1.1e-67 228.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX47048.1 - 4.1e-33 114.8 0.0 4.5e-33 114.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX47048.1 - 7.2e-08 32.1 0.0 1.5e-07 31.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EKX47048.1 - 0.0014 17.5 0.0 0.002 17.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EKX47048.1 - 0.0041 16.5 0.8 0.016 14.6 0.8 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX47048.1 - 0.018 15.0 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family EcKinase PF02958.20 EKX47048.1 - 0.05 12.9 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.22 EKX47048.1 - 0.052 13.1 0.1 0.075 12.6 0.1 1.2 1 0 0 1 1 1 0 RIO1 family SPT16 PF08644.11 EKX47049.1 - 0.072 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) CaM_bdg_C0 PF10562.9 EKX47049.1 - 7.3 6.7 7.2 0.71 10.0 0.5 2.5 3 0 0 3 3 3 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit CaM_bdg_C0 PF10562.9 EKX47050.1 - 9.3 6.4 7.3 1.1 9.4 0.9 2.5 3 0 0 3 3 3 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit PHD PF00628.29 EKX47051.1 - 7.5e-24 83.4 21.6 6.4e-13 48.4 6.0 2.9 2 0 0 2 2 2 2 PHD-finger SAP PF02037.27 EKX47051.1 - 2.5e-14 52.6 9.7 0.00041 20.0 1.0 4.8 4 0 0 4 4 4 4 SAP domain zf-PHD-like PF15446.6 EKX47051.1 - 0.0032 17.1 10.3 0.15 11.7 1.6 3.0 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 EKX47051.1 - 0.012 15.1 15.2 0.047 13.3 1.5 3.6 3 0 0 3 3 3 0 PHD-finger zf-HC5HC2H_2 PF13832.6 EKX47051.1 - 0.45 10.7 3.0 2.5 8.3 0.5 2.7 2 0 0 2 2 2 0 PHD-zinc-finger like domain FYVE_2 PF02318.16 EKX47051.1 - 1.1 9.5 15.0 0.86 9.8 0.6 4.1 2 2 1 3 3 3 0 FYVE-type zinc finger zf-RING_2 PF13639.6 EKX47051.1 - 7.3 7.0 19.6 3.1 8.2 5.8 2.8 2 0 0 2 2 2 0 Ring finger domain zf-HC5HC2H PF13771.6 EKX47051.1 - 9 6.6 10.9 17 5.8 2.6 2.9 2 1 0 2 2 2 0 PHD-like zinc-binding domain Aldedh PF00171.22 EKX47052.1 - 1.4e-36 126.0 0.0 1.8e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FMO-like PF00743.19 EKX47053.1 - 6.2e-57 193.2 0.0 9.9e-24 83.6 0.0 3.1 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EKX47053.1 - 4.3e-13 49.2 0.8 4.3e-07 29.5 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EKX47053.1 - 4.4e-10 39.3 0.0 4.7e-06 26.0 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EKX47053.1 - 1.3e-08 35.0 0.1 3.6e-08 33.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EKX47053.1 - 4.5e-06 26.0 1.6 7.4e-06 25.3 1.6 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EKX47053.1 - 1.2e-05 24.2 1.4 1.9e-05 23.5 1.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 EKX47053.1 - 7.2e-05 22.3 0.1 0.00015 21.2 0.1 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 EKX47053.1 - 0.00027 20.4 0.0 0.00039 19.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EKX47053.1 - 0.0013 18.4 0.3 0.0035 17.0 0.3 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EKX47053.1 - 0.0015 17.9 0.1 0.0025 17.1 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EKX47053.1 - 0.0015 17.8 0.0 0.0031 16.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain IlvN PF07991.12 EKX47053.1 - 0.0016 18.1 0.2 0.0034 17.0 0.1 1.6 2 0 0 2 2 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_9 PF13454.6 EKX47053.1 - 0.0022 18.0 0.4 0.012 15.6 0.3 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 EKX47053.1 - 0.0038 16.4 0.6 0.28 10.3 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EKX47053.1 - 0.0042 16.4 0.3 0.014 14.7 0.1 1.7 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 EKX47053.1 - 0.0044 16.2 0.4 0.0062 15.7 0.4 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 EKX47053.1 - 0.0081 16.7 2.5 0.0092 16.5 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EKX47053.1 - 0.011 15.1 0.1 0.16 11.3 0.1 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EKX47053.1 - 0.013 15.9 0.0 0.24 11.8 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding MCRA PF06100.11 EKX47053.1 - 0.078 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 MCRA family F420_oxidored PF03807.17 EKX47053.1 - 0.083 13.5 0.1 0.73 10.4 1.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EKX47053.1 - 0.13 12.4 0.1 1.6 8.8 0.1 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 EKX47053.1 - 0.13 11.9 1.0 0.35 10.5 0.4 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EKX47053.1 - 0.17 11.7 1.7 0.29 11.0 1.7 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EKX47053.1 - 0.18 11.8 0.5 0.36 10.8 0.5 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus zf-RING_2 PF13639.6 EKX47054.1 - 1.6e-12 47.5 9.2 2e-12 47.2 9.2 1.1 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX47054.1 - 1.3e-09 37.7 9.8 1.8e-09 37.3 9.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EKX47054.1 - 9.6e-09 34.8 4.0 9.6e-09 34.8 4.0 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 EKX47054.1 - 2.1e-08 33.9 8.7 2.9e-08 33.4 8.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX47054.1 - 7.9e-08 32.5 11.2 4.4e-07 30.1 11.2 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EKX47054.1 - 2.4e-05 24.3 3.6 2.4e-05 24.3 3.6 1.4 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EKX47054.1 - 0.0001 22.3 6.3 0.00084 19.3 6.3 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EKX47054.1 - 0.00011 21.9 6.3 0.00015 21.5 6.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX47054.1 - 0.0012 18.8 8.2 0.002 18.0 8.3 1.4 1 1 0 1 1 1 1 zinc-RING finger domain RecR PF02132.15 EKX47054.1 - 0.017 14.6 3.2 0.43 10.2 0.6 2.4 2 0 0 2 2 2 0 RecR protein Prok-RING_4 PF14447.6 EKX47054.1 - 0.047 13.5 9.7 0.23 11.3 10.1 1.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EKX47054.1 - 0.13 12.1 7.4 0.61 9.9 7.8 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 EKX47054.1 - 0.17 12.1 8.9 2.9 8.1 9.0 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 EKX47054.1 - 0.19 11.3 8.5 0.4 10.4 8.5 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 EKX47054.1 - 0.35 11.2 7.3 0.51 10.7 7.3 1.3 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 EKX47054.1 - 1.1 9.3 10.0 2.3 8.2 10.0 1.6 1 1 0 1 1 1 0 PHD-finger LCAT PF02450.15 EKX47055.1 - 7.3e-81 272.3 0.0 9.6e-81 271.9 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 EKX47055.1 - 0.0024 18.5 0.4 0.004 17.8 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family NopRA1 PF16201.5 EKX47056.1 - 1.9e-22 79.8 0.0 3.3e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 Npa1 PF11707.8 EKX47057.1 - 5.5e-32 111.4 2.6 1.2e-31 110.3 2.6 1.6 1 1 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Bac_rhodopsin PF01036.18 EKX47058.1 - 5.1e-17 62.2 8.2 8e-17 61.6 8.2 1.2 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein SRF-TF PF00319.18 EKX47059.1 - 4.5e-19 67.7 0.2 5.7e-19 67.3 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) RETICULATA-like PF11891.8 EKX47060.1 - 2.6e-22 79.5 0.0 3.9e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Protein RETICULATA-related WW PF00397.26 EKX47061.1 - 1.5e-10 40.9 0.1 2.3e-10 40.3 0.1 1.3 1 0 0 1 1 1 1 WW domain PX PF00787.24 EKX47063.1 - 2.5e-24 85.4 0.0 3.6e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 PX domain SCIMP PF15050.6 EKX47063.1 - 0.1 13.1 0.0 0.15 12.5 0.0 1.1 1 0 0 1 1 1 0 SCIMP protein GBP PF02263.19 EKX47064.1 - 1.4e-26 93.4 0.0 2.5e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 EKX47064.1 - 4.8e-14 52.5 1.3 9.3e-14 51.5 1.3 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain AAA_11 PF13086.6 EKX47064.1 - 0.34 10.7 2.1 0.39 10.4 0.7 1.7 2 0 0 2 2 2 0 AAA domain Val_tRNA-synt_C PF10458.9 EKX47064.1 - 0.41 11.0 3.7 4.5 7.6 0.3 2.7 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Pkinase PF00069.25 EKX47066.1 - 1.9e-35 122.5 0.0 1.4e-32 113.1 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EKX47066.1 - 1e-33 116.8 0.0 7e-30 104.2 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase TIG PF01833.24 EKX47066.1 - 4.1e-05 23.6 2.9 0.029 14.4 0.1 2.9 3 0 0 3 3 3 2 IPT/TIG domain Haspin_kinase PF12330.8 EKX47066.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Protein_K PF12283.8 EKX47067.1 - 0.05 13.8 0.3 0.51 10.6 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage protein K DUF3537 PF12056.8 EKX47067.1 - 0.068 12.0 0.0 4.5 6.0 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3537) Utp12 PF04003.12 EKX47068.1 - 0.011 16.0 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 0 Dip2/Utp12 Family Vac14_Fab1_bd PF12755.7 EKX47068.1 - 0.031 14.9 0.0 0.052 14.1 0.0 1.4 1 1 0 1 1 1 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EKX47068.1 - 0.069 13.7 0.2 1.1 9.9 0.1 2.4 2 0 0 2 2 2 0 HEAT-like repeat Tti2 PF10521.9 EKX47068.1 - 0.08 12.5 0.1 2.3 7.7 0.0 2.1 1 1 2 3 3 3 0 Tti2 family Glycos_transf_1 PF00534.20 EKX47069.1 - 5.4e-28 97.7 0.0 9.6e-28 96.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EKX47069.1 - 1.2e-24 87.3 0.0 2.5e-24 86.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EKX47069.1 - 1.8e-17 63.9 0.0 3e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EKX47069.1 - 3e-10 40.8 0.0 7.2e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EKX47069.1 - 0.00024 21.4 0.0 0.00065 20.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 EKX47069.1 - 0.00051 20.1 0.0 0.0016 18.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase 4-like HeH PF12949.7 EKX47069.1 - 0.15 11.8 0.0 1.8 8.4 0.0 2.1 2 0 0 2 2 2 0 HeH/LEM domain HECT_2 PF09814.9 EKX47070.1 - 0.017 14.0 0.1 0.017 14.0 0.1 1.1 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding SNF2_N PF00176.23 EKX47071.1 - 3e-25 88.7 0.0 4.8e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX47071.1 - 8.4e-09 35.8 0.0 2.9e-08 34.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX47071.1 - 0.0019 18.2 0.0 0.0064 16.5 0.0 1.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EKX47071.1 - 0.0022 17.8 0.0 0.0072 16.1 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Orexin PF02072.15 EKX47072.1 - 0.31 11.0 1.7 0.85 9.6 1.7 1.7 1 0 0 1 1 1 0 Prepro-orexin Sec23_trunk PF04811.15 EKX47073.1 - 2.6e-66 223.7 0.0 3.6e-66 223.2 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EKX47073.1 - 6.6e-28 97.3 0.1 1.6e-27 96.0 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EKX47073.1 - 9.6e-23 80.0 0.0 1.8e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EKX47073.1 - 1.8e-14 53.5 8.9 4.2e-14 52.3 8.9 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EKX47073.1 - 4.6e-13 48.9 0.0 1.1e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EKX47073.1 - 0.013 14.9 0.2 0.045 13.2 0.2 1.9 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain VWA_2 PF13519.6 EKX47073.1 - 0.039 14.6 0.0 0.84 10.3 0.0 2.4 2 0 0 2 2 2 0 von Willebrand factor type A domain BRO1 PF03097.18 EKX47074.1 - 3.4e-75 253.3 2.7 3.4e-75 253.3 2.7 2.0 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EKX47074.1 - 4.2e-42 144.5 16.7 4.2e-42 144.5 16.7 2.0 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV WW PF00397.26 EKX47074.1 - 2.8e-12 46.5 1.7 5.4e-12 45.6 1.7 1.5 1 0 0 1 1 1 1 WW domain EutK_C PF16365.5 EKX47074.1 - 0.0082 16.2 0.7 0.027 14.5 0.7 1.9 1 0 0 1 1 1 1 Ethanolamine utilization protein EutK C-terminus YmgB PF10798.8 EKX47074.1 - 0.033 14.0 0.3 0.14 12.0 0.1 2.2 2 0 0 2 2 2 0 Biofilm development protein YmgB/AriR Hydrophob_seed PF14547.6 EKX47074.1 - 0.092 13.0 0.4 0.29 11.4 0.4 1.8 1 0 0 1 1 1 0 Hydrophobic seed protein Complex1_LYR_2 PF13233.6 EKX47074.1 - 0.1 13.4 2.5 0.53 11.1 0.3 3.0 2 0 0 2 2 2 0 Complex1_LYR-like HD_2 PF12917.7 EKX47074.1 - 0.16 11.7 2.3 0.59 9.9 2.3 1.9 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme DDE_Tnp_IS66 PF03050.14 EKX47074.1 - 1.4 8.4 6.2 0.68 9.4 0.4 2.8 2 0 0 2 2 2 0 Transposase IS66 family ING PF12998.7 EKX47074.1 - 4.5 7.9 11.0 2.5 8.7 1.0 4.1 4 1 0 4 4 4 0 Inhibitor of growth proteins N-terminal histone-binding Peptidase_M41 PF01434.18 EKX47076.1 - 4.5e-68 228.9 0.2 7.6e-68 228.1 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EKX47076.1 - 3.5e-45 153.7 0.0 9.2e-45 152.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EKX47076.1 - 5.8e-12 45.2 0.0 1.9e-11 43.6 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EKX47076.1 - 2.9e-05 24.1 0.1 0.00045 20.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EKX47076.1 - 0.00033 20.0 0.0 0.00059 19.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 EKX47076.1 - 0.002 17.9 0.0 0.0063 16.3 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain FtsH_ext PF06480.15 EKX47076.1 - 0.0022 18.3 0.0 0.01 16.2 0.0 2.2 2 0 0 2 2 1 1 FtsH Extracellular AAA_16 PF13191.6 EKX47076.1 - 0.0023 18.3 1.4 0.062 13.7 0.1 2.7 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EKX47076.1 - 0.008 16.4 0.7 0.17 12.2 0.1 2.7 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.21 EKX47076.1 - 0.011 15.1 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EKX47076.1 - 0.032 14.4 0.0 0.068 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EKX47076.1 - 0.043 13.6 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 EKX47076.1 - 0.045 13.9 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 EKX47076.1 - 0.078 13.4 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EKX47076.1 - 0.098 12.9 0.0 0.35 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EKX47076.1 - 0.099 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EKX47076.1 - 0.16 11.9 0.0 0.72 9.8 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 EKX47076.1 - 0.18 12.4 0.0 0.38 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EKX47076.1 - 4 6.9 5.5 0.94 8.9 0.1 2.6 4 0 0 4 4 4 0 PhoH-like protein Ank_4 PF13637.6 EKX47078.1 - 7.7e-13 48.7 0.0 3.7e-08 33.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX47078.1 - 3.6e-11 43.1 0.0 1.4e-08 34.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX47078.1 - 7.6e-11 42.5 0.0 2e-10 41.1 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX47078.1 - 2.1e-07 31.1 0.0 1.9e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EKX47078.1 - 3.6e-07 30.0 0.0 9.2e-05 22.6 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Med16 PF11635.8 EKX47078.1 - 0.35 8.8 1.9 0.44 8.4 1.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 16 WD40 PF00400.32 EKX47079.1 - 1.3e-33 114.4 27.4 0.00018 22.3 0.2 12.5 12 0 0 12 12 12 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX47079.1 - 6e-11 42.5 0.0 0.31 11.4 0.0 7.2 5 3 2 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EKX47079.1 - 0.0035 17.2 0.0 0.39 10.6 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.6 EKX47079.1 - 0.1 13.1 0.0 7.4 7.2 0.0 3.4 2 0 0 2 2 2 0 PQQ-like domain SCAB-ABD PF16711.5 EKX47080.1 - 0.11 12.4 0.1 0.17 11.8 0.1 1.2 1 0 0 1 1 1 0 Actin-binding domain of plant-specific actin-binding protein Amidohydro_2 PF04909.14 EKX47082.1 - 7.5e-34 117.8 0.3 1e-33 117.4 0.3 1.2 1 0 0 1 1 1 1 Amidohydrolase Hormone_3 PF00159.18 EKX47082.1 - 0.54 10.4 4.2 3.7 7.7 0.2 3.3 4 0 0 4 4 4 0 Pancreatic hormone peptide Brix PF04427.18 EKX47083.1 - 3.3e-29 102.4 0.1 4.8e-29 101.8 0.1 1.2 1 0 0 1 1 1 1 Brix domain Hpr_kinase_N PF02603.16 EKX47083.1 - 0.0082 16.2 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 HPr Serine kinase N terminus ATP-synt_E PF05680.12 EKX47083.1 - 0.38 11.1 12.0 0.66 10.4 11.2 1.8 1 1 0 1 1 1 0 ATP synthase E chain Sec62 PF03839.16 EKX47083.1 - 1.9 8.0 5.9 1.7 8.1 3.4 2.0 2 0 0 2 2 2 0 Translocation protein Sec62 RNA_pol_3_Rpc31 PF11705.8 EKX47083.1 - 9.6 6.4 16.9 16 5.7 16.9 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2423 PF10338.9 EKX47084.1 - 0.25 11.6 4.0 2.2 8.6 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2423) Cation_efflux PF01545.21 EKX47086.1 - 1.1e-46 159.0 7.3 1.4e-46 158.7 7.3 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EKX47086.1 - 5.4e-12 45.7 0.2 1.2e-11 44.6 0.2 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Alpha_kinase PF02816.18 EKX47087.1 - 6.1e-31 108.0 0.5 8.4e-31 107.5 0.5 1.2 1 0 0 1 1 1 1 Alpha-kinase family EFG_IV PF03764.18 EKX47087.1 - 0.18 11.6 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Elongation factor G, domain IV bZIP_1 PF00170.21 EKX47088.1 - 1.1e-12 47.8 13.3 1.8e-12 47.2 13.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EKX47088.1 - 8.4e-08 32.2 11.7 8.4e-08 32.2 11.7 1.9 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.17 EKX47088.1 - 8.7e-07 29.4 8.7 2e-06 28.2 8.7 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor UPF0184 PF03670.13 EKX47088.1 - 0.04 14.3 1.1 0.1 13.0 1.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Pox_G5 PF04599.12 EKX47088.1 - 0.44 9.5 3.0 0.58 9.1 3.0 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein DUF4692 PF15763.5 EKX47088.1 - 5.7 7.4 7.9 8.7 6.8 6.8 1.8 1 1 1 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) Tcp10_C PF07202.13 EKX47089.1 - 1.3e-19 70.9 0.0 1.3e-19 70.8 0.0 1.0 1 0 0 1 1 1 1 T-complex protein 10 C-terminus MIR PF02815.19 EKX47090.1 - 0.0029 17.5 0.1 0.53 10.1 0.0 2.2 2 0 0 2 2 2 2 MIR domain F-box-like PF12937.7 EKX47091.1 - 0.0031 17.4 0.3 0.0031 17.4 0.3 2.8 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 EKX47091.1 - 0.0043 16.9 0.2 0.0043 16.9 0.2 4.7 4 0 0 4 4 4 1 F-box domain LRR_8 PF13855.6 EKX47091.1 - 2.5 7.9 12.2 4.3 7.2 0.3 5.6 4 1 1 5 5 5 0 Leucine rich repeat LRR_6 PF13516.6 EKX47091.1 - 2.8 8.2 9.0 3.8 7.8 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich repeat HhH-GPD PF00730.25 EKX47092.1 - 0.00056 20.3 0.0 0.00066 20.1 0.0 1.1 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Mito_carr PF00153.27 EKX47094.1 - 8.7e-36 121.7 6.9 6.9e-13 48.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ketoacyl-synt PF00109.26 EKX47095.1 - 2.7e-29 102.5 3.5 3.8e-28 98.7 3.5 2.2 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EKX47095.1 - 0.00021 21.3 0.1 0.00079 19.4 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain NOA36 PF06524.12 EKX47095.1 - 0.79 9.0 9.0 1.4 8.1 9.0 1.3 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 EKX47095.1 - 2.8 8.4 15.5 5.6 7.4 15.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2457 PF10446.9 EKX47095.1 - 2.9 6.9 10.8 4.9 6.2 10.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 EKX47095.1 - 7.9 4.4 8.2 11 3.9 8.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi LRR_4 PF12799.7 EKX47096.1 - 2e-12 47.1 31.0 2.1e-05 24.8 3.4 4.5 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX47096.1 - 5e-12 45.7 1.6 9.1e-09 35.0 1.2 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 EKX47096.1 - 2.6e-07 30.3 19.3 0.00068 19.3 5.5 3.9 2 1 1 3 3 3 3 Leucine rich repeat TMPIT PF07851.13 EKX47096.1 - 0.0012 18.2 5.5 0.0022 17.3 5.5 1.3 1 0 0 1 1 1 1 TMPIT-like protein LRR_6 PF13516.6 EKX47096.1 - 0.027 14.5 16.0 1.6 9.0 0.3 5.5 5 0 0 5 5 5 0 Leucine Rich repeat Vac_Fusion PF02346.16 EKX47096.1 - 0.25 11.0 1.7 1.3 8.7 0.8 2.7 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 DUF1664 PF07889.12 EKX47096.1 - 0.37 10.8 3.4 0.4 10.7 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2570 PF10828.8 EKX47096.1 - 0.62 9.9 5.1 1.8 8.5 5.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) CCDC92 PF14916.6 EKX47096.1 - 1.2 9.0 7.1 0.095 12.5 1.8 1.9 2 0 0 2 2 2 0 Coiled-coil domain of unknown function LRR_1 PF00560.33 EKX47096.1 - 2.8 8.9 16.5 16 6.6 0.9 5.8 5 2 0 5 5 4 0 Leucine Rich Repeat Phage_GPO PF05929.11 EKX47096.1 - 2.8 7.5 9.4 0.5 9.9 4.7 1.9 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase BST2 PF16716.5 EKX47096.1 - 2.8 8.6 10.3 2.2 8.9 7.9 2.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 YabA PF06156.13 EKX47096.1 - 3.7 8.2 6.6 7.1 7.3 5.1 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Kinetochor_Ybp2 PF08568.10 EKX47097.1 - 4.8e-14 51.8 2.5 9.6e-11 40.9 0.1 2.6 3 0 0 3 3 3 2 Uncharacterised protein family, YAP/Alf4/glomulin SKIP_SNW PF02731.15 EKX47098.1 - 0.097 12.3 64.3 1.5 8.5 3.0 8.6 2 1 10 12 12 12 0 SKIP/SNW domain Phage_antitermQ PF06530.12 EKX47098.1 - 0.2 11.6 25.5 7 6.6 0.3 9.6 1 1 11 12 12 12 0 Phage antitermination protein Q Apolipoprotein PF01442.18 EKX47098.1 - 6.5 6.6 95.1 3.5 7.5 38.2 4.1 1 1 2 3 3 3 0 Apolipoprotein A1/A4/E domain zf-4CXXC_R1 PF10497.9 EKX47099.1 - 5.6e-06 26.5 26.0 8.1e-06 26.0 26.0 1.2 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 HLH PF00010.26 EKX47100.1 - 6.5e-06 26.0 2.4 2.1e-05 24.4 2.4 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Lambda_Kil PF06301.11 EKX47100.1 - 0.00029 20.4 0.0 0.00073 19.1 0.0 1.6 1 0 0 1 1 1 1 Bacteriophage lambda Kil protein TPR_12 PF13424.6 EKX47100.1 - 0.002 18.3 0.1 0.002 18.3 0.1 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX47100.1 - 0.0035 17.2 0.1 0.015 15.1 0.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_21 PF09976.9 EKX47100.1 - 0.067 12.9 2.6 0.14 11.8 0.5 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 EKX47100.1 - 0.084 13.1 0.1 0.31 11.3 0.1 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Csm2_III-A PF03750.13 EKX47100.1 - 0.28 12.0 2.7 0.53 11.1 1.1 2.2 2 0 0 2 2 2 0 Csm2 Type III-A MerR-DNA-bind PF09278.11 EKX47100.1 - 0.3 11.6 0.1 0.3 11.6 0.1 3.4 3 1 1 4 4 4 0 MerR, DNA binding Jnk-SapK_ap_N PF09744.9 EKX47102.1 - 0.0016 18.7 4.3 0.0016 18.7 4.3 3.8 2 1 1 3 3 3 1 JNK_SAPK-associated protein-1 TolA_bind_tri PF16331.5 EKX47102.1 - 0.0035 17.4 5.2 0.0035 17.4 5.2 5.0 4 1 1 5 5 5 1 TolA binding protein trimerisation KASH_CCD PF14662.6 EKX47102.1 - 0.0052 16.6 6.2 0.0052 16.6 6.2 3.3 2 1 1 3 3 3 2 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 EKX47102.1 - 0.0066 15.8 10.0 0.0066 15.8 10.0 3.7 1 1 2 3 3 2 1 Growth-arrest specific micro-tubule binding CENP-H PF05837.12 EKX47102.1 - 0.017 15.6 3.5 0.017 15.6 3.5 4.2 2 1 2 4 4 4 0 Centromere protein H (CENP-H) Tropomyosin_1 PF12718.7 EKX47102.1 - 0.019 15.2 14.0 0.019 15.2 14.0 3.8 1 1 2 3 3 2 0 Tropomyosin like Bap31_Bap29_C PF18035.1 EKX47102.1 - 0.019 14.9 8.3 0.019 14.9 8.3 5.2 5 1 1 6 6 5 0 Bap31/Bap29 cytoplasmic coiled-coil domain Myosin_tail_1 PF01576.19 EKX47102.1 - 0.065 11.0 59.7 0.064 11.1 20.9 2.0 1 1 1 2 2 2 0 Myosin tail LPP PF04728.13 EKX47102.1 - 0.15 12.5 0.4 0.15 12.5 0.4 4.4 4 1 0 4 4 4 0 Lipoprotein leucine-zipper MbeD_MobD PF04899.12 EKX47102.1 - 3 8.0 13.7 0.39 10.9 0.1 3.9 3 2 0 3 3 3 0 MbeD/MobD like ApoO PF09769.9 EKX47102.1 - 3.4 7.6 11.0 0.48 10.4 1.1 3.7 2 2 1 3 3 3 0 Apolipoprotein O DUF4407 PF14362.6 EKX47102.1 - 6 6.1 43.3 4.1 6.7 12.8 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 EKX47102.1 - 9.8 3.9 43.8 0.35 8.7 7.1 2.6 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family MFS_1 PF07690.16 EKX47104.1 - 3.3e-16 59.2 12.4 5.1e-16 58.6 12.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 EKX47104.1 - 0.051 11.9 0.2 0.14 10.5 0.2 1.7 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Neprosin PF03080.15 EKX47104.1 - 0.18 11.1 0.0 0.38 10.1 0.0 1.4 1 0 0 1 1 1 0 Neprosin PCI PF01399.27 EKX47105.1 - 1.5e-16 60.8 0.2 2.3e-16 60.2 0.2 1.3 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.9 EKX47105.1 - 3.7e-09 36.5 1.1 1.4e-08 34.6 0.0 2.4 3 0 0 3 3 3 1 26S proteasome subunit RPN7 Mei4 PF13971.6 EKX47105.1 - 0.022 14.2 0.0 0.032 13.7 0.0 1.1 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 Type_III_YscX PF09474.10 EKX47105.1 - 0.066 13.5 0.4 0.14 12.5 0.3 1.6 1 1 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) ATG16 PF08614.11 EKX47106.1 - 0.00024 21.4 16.7 0.00024 21.4 16.7 6.0 1 1 4 5 5 5 1 Autophagy protein 16 (ATG16) Lebercilin PF15619.6 EKX47106.1 - 0.00074 19.2 16.9 0.00074 19.2 16.9 6.3 3 3 2 6 6 6 1 Ciliary protein causing Leber congenital amaurosis disease Mod_r PF07200.13 EKX47106.1 - 0.0036 17.4 15.0 0.0036 17.4 15.0 6.5 2 2 4 6 6 6 1 Modifier of rudimentary (Mod(r)) protein FlaC_arch PF05377.11 EKX47106.1 - 0.0065 16.8 4.4 0.0065 16.8 4.4 8.6 9 2 1 10 10 10 2 Flagella accessory protein C (FlaC) Fez1 PF06818.15 EKX47106.1 - 0.015 15.8 15.9 0.015 15.8 15.9 5.3 1 1 4 5 5 5 0 Fez1 NPV_P10 PF05531.12 EKX47106.1 - 3.1 8.3 32.4 0.31 11.6 1.9 7.1 5 2 1 6 6 6 0 Nucleopolyhedrovirus P10 protein DUF4200 PF13863.6 EKX47107.1 - 0.008 16.6 12.8 0.008 16.6 12.8 10.3 5 2 5 10 10 10 2 Domain of unknown function (DUF4200) SET PF00856.28 EKX47109.1 - 2.6e-13 50.7 4.7 3e-13 50.5 0.0 2.9 2 1 0 2 2 2 1 SET domain CCDC50_N PF15295.6 EKX47109.1 - 0.041 14.0 14.5 0.069 13.3 7.6 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 50 N-terminus RRN9 PF10680.9 EKX47109.1 - 4.3 7.7 5.3 0.75 10.1 0.3 2.3 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor Agenet PF05641.12 EKX47110.1 - 5e-08 33.3 5.1 0.021 15.3 0.1 4.8 5 0 0 5 5 5 2 Agenet domain MBT PF02820.18 EKX47110.1 - 1.6e-06 28.4 0.1 0.21 12.0 0.0 3.8 4 0 0 4 4 4 2 mbt repeat PHD PF00628.29 EKX47110.1 - 0.0003 20.6 3.6 0.0003 20.6 3.6 2.3 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.22 EKX47110.1 - 0.00071 19.4 14.4 0.0042 16.9 7.8 3.6 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Tudor_4 PF18358.1 EKX47110.1 - 0.002 17.7 1.2 8 6.2 0.0 3.8 3 0 0 3 3 3 2 Histone methyltransferase Tudor domain zf-CHY PF05495.12 EKX47110.1 - 0.015 15.7 8.2 0.064 13.8 8.2 2.1 1 0 0 1 1 1 0 CHY zinc finger LBR_tudor PF09465.10 EKX47110.1 - 0.049 13.4 0.1 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain RAG2_PHD PF13341.6 EKX47110.1 - 0.11 12.6 0.3 2.4 8.3 0.2 2.5 2 0 0 2 2 2 0 RAG2 PHD domain DUF3104 PF11302.8 EKX47110.1 - 0.14 12.0 2.1 43 4.0 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3104) TUDOR_5 PF18359.1 EKX47110.1 - 0.16 11.7 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain 1 Ribosomal_L32p PF01783.23 EKX47110.1 - 0.65 10.3 3.4 0.75 10.1 0.4 2.8 2 0 0 2 2 2 0 Ribosomal L32p protein family C1_2 PF03107.16 EKX47110.1 - 1.8 8.9 11.2 0.54 10.6 4.5 2.7 1 1 1 2 2 2 0 C1 domain zf-ribbon_3 PF13248.6 EKX47110.1 - 2.5 7.6 9.0 25 4.5 0.8 3.8 2 1 1 3 3 3 0 zinc-ribbon domain DZR PF12773.7 EKX47110.1 - 3.1 7.9 10.3 38 4.4 10.4 2.5 1 1 0 1 1 1 0 Double zinc ribbon SprB PF13573.6 EKX47111.1 - 0.00048 19.8 0.0 9 6.2 0.7 4.3 4 0 0 4 4 4 3 SprB repeat Baculo_LEF5 PF04838.12 EKX47112.1 - 0.052 13.6 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 PelG PF16933.5 EKX47113.1 - 0.87 8.4 10.4 2.7 6.8 2.0 2.3 2 0 0 2 2 2 0 Putative exopolysaccharide Exporter (EPS-E) Pkinase PF00069.25 EKX47114.1 - 1.9e-67 227.5 0.0 2.1e-67 227.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX47114.1 - 4.3e-29 101.6 0.0 5.6e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX47114.1 - 1.4e-08 34.4 0.1 9.9e-05 21.8 0.0 2.4 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.14 EKX47114.1 - 9.3e-06 25.1 0.0 1.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX47114.1 - 0.0012 18.9 0.1 0.0078 16.2 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EKX47114.1 - 0.0027 17.4 0.0 0.0042 16.7 0.0 1.4 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 EKX47114.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase ABC1 PF03109.16 EKX47114.1 - 0.026 14.7 0.0 0.061 13.5 0.0 1.6 1 0 0 1 1 1 0 ABC1 family LysM PF01476.20 EKX47115.1 - 5e-13 48.9 0.0 1.1e-07 31.8 0.0 2.4 2 0 0 2 2 2 2 LysM domain Na_sulph_symp PF00939.19 EKX47116.1 - 7.3e-34 117.6 21.4 1e-33 117.1 21.4 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EKX47116.1 - 2.6e-29 102.4 21.4 4.1e-29 101.7 21.4 1.3 1 0 0 1 1 1 1 Citrate transporter PDZ PF00595.24 EKX47117.1 - 8.4e-14 51.7 0.2 6.7e-08 32.8 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EKX47117.1 - 5.5e-13 48.5 1.8 1e-06 28.4 0.2 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX47117.1 - 2e-12 47.3 0.1 1e-06 29.0 0.0 2.3 2 0 0 2 2 2 2 PDZ domain DUF3394 PF11874.8 EKX47117.1 - 0.0018 18.0 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3394) TEX13 PF15186.6 EKX47117.1 - 0.073 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family BUD22 PF09073.10 EKX47118.1 - 0.00019 20.9 15.3 0.00022 20.7 15.3 1.1 1 0 0 1 1 1 1 BUD22 ARL2_Bind_BART PF11527.8 EKX47118.1 - 0.00068 19.7 0.9 0.0011 19.0 0.9 1.3 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Mpp10 PF04006.12 EKX47118.1 - 0.0011 17.5 14.4 0.0011 17.5 14.4 1.1 1 0 0 1 1 1 1 Mpp10 protein SpoIIIAH PF12685.7 EKX47118.1 - 0.045 13.6 3.4 0.042 13.7 3.4 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein SAPS PF04499.15 EKX47118.1 - 0.12 11.2 4.1 0.11 11.3 4.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.22 EKX47118.1 - 0.64 9.2 1.2 0.58 9.3 1.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 EKX47118.1 - 0.88 8.3 6.4 1.1 8.0 6.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nop14 PF04147.12 EKX47118.1 - 0.99 7.5 31.2 0.31 9.2 28.6 1.5 2 0 0 2 2 2 0 Nop14-like family SDA1 PF05285.12 EKX47118.1 - 2.1 7.7 30.2 2.9 7.2 30.2 1.1 1 0 0 1 1 1 0 SDA1 HSP90 PF00183.18 EKX47118.1 - 2.4 7.0 7.9 2.9 6.7 7.9 1.3 1 0 0 1 1 1 0 Hsp90 protein DUF2457 PF10446.9 EKX47118.1 - 6.3 5.8 42.8 9.3 5.3 42.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ank_4 PF13637.6 EKX47119.1 - 5.2e-15 55.6 0.8 4.2e-11 43.1 0.3 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX47119.1 - 9.1e-13 48.0 0.5 2.1e-07 31.0 0.2 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EKX47119.1 - 1.2e-10 41.9 0.1 1.6e-10 41.4 0.1 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX47119.1 - 1.5e-08 34.7 1.1 4.3e-08 33.3 0.7 1.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX47119.1 - 3e-08 33.3 0.4 0.00012 22.2 0.1 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ribosomal_L5 PF00281.19 EKX47120.1 - 2.2e-18 66.3 0.0 5e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 EKX47120.1 - 2.2e-18 66.2 0.0 3.3e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus HTH_ABP1_N PF18107.1 EKX47120.1 - 0.0015 18.2 1.7 0.0018 18.0 0.4 1.7 2 0 0 2 2 2 1 Fission yeast centromere protein N-terminal domain DUF5645 PF18713.1 EKX47120.1 - 0.037 14.3 0.0 0.065 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5645) Gp_dh_C PF02800.20 EKX47121.1 - 4.3e-66 221.4 0.0 6.1e-66 220.9 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EKX47121.1 - 9e-36 122.3 0.0 2e-35 121.1 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EKX47121.1 - 0.00094 19.3 0.1 0.26 11.4 0.0 2.5 2 0 0 2 2 2 2 Dihydrodipicolinate reductase, N-terminus Alba PF01918.21 EKX47121.1 - 0.072 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Alba 2-Hacid_dh_C PF02826.19 EKX47121.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FHA PF00498.26 EKX47122.1 - 5.9e-19 68.2 0.0 5.8e-09 36.2 0.0 2.6 2 0 0 2 2 2 2 FHA domain Yop-YscD_cpl PF16697.5 EKX47122.1 - 8.8e-15 54.8 0.0 6.5e-06 26.4 0.0 2.7 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain LRR_6 PF13516.6 EKX47122.1 - 2.7e-09 36.3 3.1 0.0058 16.6 0.0 6.2 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 EKX47122.1 - 0.00093 19.5 0.2 0.72 10.4 0.0 4.1 3 1 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX47122.1 - 0.0041 17.5 1.3 45 5.2 0.0 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat Preseq_ALAS PF09029.10 EKX47122.1 - 0.12 12.8 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence CPDase PF07823.11 EKX47123.1 - 6.7e-11 42.3 0.0 1.3e-10 41.3 0.0 1.5 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 EKX47123.1 - 4.8e-05 23.3 0.0 0.00024 21.0 0.0 2.0 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily Nop14 PF04147.12 EKX47123.1 - 0.23 9.6 6.0 0.29 9.3 6.0 1.1 1 0 0 1 1 1 0 Nop14-like family Adaptin_N PF01602.20 EKX47124.1 - 7.1e-05 21.6 0.2 0.00012 20.8 0.2 1.3 1 0 0 1 1 1 1 Adaptin N terminal region MMS19_C PF12460.8 EKX47124.1 - 0.086 11.9 0.1 0.24 10.5 0.1 1.7 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal YrhK PF14145.6 EKX47125.1 - 0.085 12.7 0.9 7.3 6.5 0.1 2.4 2 0 0 2 2 2 0 YrhK-like protein DUF1980 PF09323.10 EKX47125.1 - 0.13 12.1 2.6 0.7 9.8 0.7 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) Cullin PF00888.22 EKX47126.1 - 1.1e-191 638.6 12.9 1.3e-191 638.4 12.9 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EKX47126.1 - 2.8e-25 88.1 1.2 8e-25 86.7 0.3 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain HbrB PF08539.11 EKX47126.1 - 0.019 15.0 0.1 0.089 12.8 0.1 2.2 1 0 0 1 1 1 0 HbrB-like HTH_IclR PF09339.10 EKX47126.1 - 0.065 13.1 0.2 2.3 8.1 0.0 3.2 3 0 0 3 3 3 0 IclR helix-turn-helix domain PRD PF00874.20 EKX47126.1 - 0.34 11.3 2.8 0.52 10.6 0.2 2.8 3 0 0 3 3 3 0 PRD domain Ank_4 PF13637.6 EKX47127.1 - 1.1e-21 76.9 0.3 2.1e-10 40.9 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX47127.1 - 1.1e-17 63.8 0.1 1.6e-11 44.2 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX47127.1 - 6.9e-16 57.9 0.0 1.1e-05 25.6 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EKX47127.1 - 2.1e-14 53.9 0.1 8.8e-07 29.4 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX47127.1 - 3.3e-12 45.4 0.0 0.00034 20.8 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat EccE PF11203.8 EKX47127.1 - 0.052 13.9 0.0 0.059 13.7 0.0 1.1 1 0 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE TPR_1 PF00515.28 EKX47128.1 - 8.1e-15 53.9 3.5 1.7e-05 24.4 0.3 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX47128.1 - 1.1e-11 43.9 5.9 0.0013 18.6 0.5 3.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX47128.1 - 2.9e-07 30.1 1.4 0.11 12.2 0.2 3.1 1 1 2 3 3 3 3 TPR repeat TPR_9 PF13371.6 EKX47128.1 - 4.5e-07 29.9 6.3 0.00024 21.2 0.4 1.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX47128.1 - 7.3e-05 23.0 1.3 0.00074 19.8 0.7 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX47128.1 - 8.8e-05 22.3 1.4 2.6 8.3 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX47128.1 - 0.00015 22.3 3.9 0.082 13.6 4.9 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX47128.1 - 0.0025 17.9 2.1 0.63 10.4 0.1 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX47128.1 - 0.0078 16.5 0.4 2.5 8.7 0.1 2.4 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX47128.1 - 0.011 15.5 0.8 0.45 10.5 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX47128.1 - 0.02 15.7 3.1 14 6.9 0.1 3.0 1 1 2 3 3 3 0 Tetratricopeptide repeat Herpes_UL25 PF01499.16 EKX47128.1 - 0.026 13.1 0.0 0.031 12.8 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family MIT PF04212.18 EKX47128.1 - 0.046 13.8 0.1 5.3 7.2 0.1 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 EKX47128.1 - 0.075 13.7 0.9 26 5.7 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Ank_4 PF13637.6 EKX47129.1 - 2.6e-16 59.7 0.0 3.3e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX47129.1 - 1.2e-15 57.9 0.0 1.8e-15 57.3 0.0 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX47129.1 - 6.5e-15 54.8 0.0 1.4e-06 28.5 0.0 2.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EKX47129.1 - 1.8e-13 50.4 0.1 6.2e-08 32.8 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX47129.1 - 1.9e-11 43.1 0.0 0.00027 21.1 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat PDZ PF00595.24 EKX47130.1 - 8.4e-13 48.5 0.0 7.4e-07 29.4 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EKX47130.1 - 5e-12 45.5 0.2 1.8e-06 27.7 0.0 2.8 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 EKX47130.1 - 1.1e-11 44.9 0.0 1.3e-05 25.5 0.0 2.3 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 EKX47130.1 - 0.00012 22.0 0.7 0.064 13.2 0.0 3.0 2 1 1 3 3 3 2 Tricorn protease PDZ domain GRASP55_65 PF04495.14 EKX47130.1 - 0.00034 20.9 0.0 0.53 10.6 0.0 2.5 1 1 2 3 3 3 2 GRASP55/65 PDZ-like domain HALZ PF02183.18 EKX47130.1 - 0.21 11.8 3.5 1.3 9.3 0.2 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.12 EKX47130.1 - 0.24 11.4 6.6 0.44 10.6 6.6 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spt4 PF06093.13 EKX47131.1 - 1.8e-19 69.6 0.3 2.2e-19 69.3 0.3 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger MCR PF18509.1 EKX47131.1 - 0.28 10.8 2.4 0.4 10.3 0.0 2.1 2 0 0 2 2 2 0 Magnetochrome domain DUF1289 PF06945.13 EKX47132.1 - 2.1e-11 43.5 0.8 4.3e-11 42.4 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) PsaD PF02531.16 EKX47133.1 - 0.019 14.5 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 PsaD DnaJ_CXXCXGXG PF00684.19 EKX47133.1 - 0.14 12.5 14.4 0.44 11.0 14.5 1.7 1 1 0 1 1 1 0 DnaJ central domain BolA PF01722.18 EKX47134.1 - 7.2e-16 58.2 0.1 2e-15 56.8 0.1 1.6 1 1 0 1 1 1 1 BolA-like protein WD40 PF00400.32 EKX47136.1 - 1.3e-35 120.7 12.1 5.2e-07 30.3 0.1 7.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX47136.1 - 1.4e-15 57.3 5.6 8.7e-06 26.0 0.2 5.3 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EKX47136.1 - 1.8e-07 31.3 0.3 0.0034 17.3 0.2 2.6 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EKX47136.1 - 0.014 14.7 0.0 0.49 9.7 0.0 2.3 1 1 1 2 2 2 0 WD40-like domain Lgl_C PF08596.10 EKX47136.1 - 0.022 13.5 0.0 0.13 10.9 0.0 2.0 2 0 0 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal SGL PF08450.12 EKX47136.1 - 0.025 14.1 0.2 1.4 8.5 0.1 2.6 1 1 2 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region PD40 PF07676.12 EKX47136.1 - 0.044 13.7 0.1 69 3.6 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 EKX47136.1 - 0.098 12.4 3.7 0.76 9.5 0.5 3.5 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain Acetyltransf_1 PF00583.25 EKX47137.1 - 3.6e-14 53.0 0.1 7.3e-14 52.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EKX47137.1 - 1.4e-08 35.0 0.2 3e-08 34.0 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EKX47137.1 - 6e-07 29.5 0.1 1.1e-06 28.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EKX47137.1 - 3.7e-06 26.8 0.0 1.1e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 EKX47137.1 - 5.2e-06 26.6 0.0 1.2e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EKX47137.1 - 0.0072 17.0 0.0 0.11 13.2 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain LMWPc PF01451.21 EKX47138.1 - 2.5e-23 83.0 0.0 2e-22 80.1 0.0 2.0 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase FancD2 PF14631.6 EKX47139.1 - 3.6 4.9 5.5 5.2 4.3 5.5 1.2 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease SAP PF02037.27 EKX47140.1 - 4.6e-13 48.6 1.3 7.4e-13 47.9 1.3 1.4 1 0 0 1 1 1 1 SAP domain Rho_N PF07498.12 EKX47140.1 - 3.2e-05 23.8 0.4 5.3e-05 23.0 0.4 1.4 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain Ribosomal_60s PF00428.19 EKX47143.1 - 9.2e-17 61.4 7.1 1.1e-16 61.1 7.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein LRR_6 PF13516.6 EKX47144.1 - 4.3e-21 73.1 26.0 0.0019 18.1 0.1 9.0 9 0 0 9 9 9 7 Leucine Rich repeat LRR_4 PF12799.7 EKX47144.1 - 2.9e-10 40.2 20.9 0.0048 17.3 0.1 5.9 3 2 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX47144.1 - 1.4e-07 31.1 14.5 1.9 9.3 0.1 8.1 9 0 0 9 9 9 3 Leucine Rich Repeat LRR_8 PF13855.6 EKX47144.1 - 6.6e-06 25.8 21.6 0.042 13.6 1.5 5.8 4 2 1 5 5 5 3 Leucine rich repeat RCC1_2 PF13540.6 EKX47145.1 - 3e-16 58.8 3.9 8.4e-09 35.0 0.2 2.3 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EKX47145.1 - 1.9e-10 41.2 1.1 3e-05 24.5 0.0 3.1 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat C2 PF00168.30 EKX47146.1 - 0.00035 20.8 0.0 0.0006 20.1 0.0 1.3 1 0 0 1 1 1 1 C2 domain C2 PF00168.30 EKX47147.1 - 0.00075 19.7 0.0 0.0013 19.0 0.0 1.3 1 0 0 1 1 1 1 C2 domain C2 PF00168.30 EKX47148.1 - 0.00027 21.2 0.0 0.00042 20.5 0.0 1.3 1 0 0 1 1 1 1 C2 domain bMG6 PF17962.1 EKX47150.1 - 0.0043 17.2 0.1 0.83 9.8 0.0 2.6 2 0 0 2 2 2 2 Bacterial macroglobulin domain 6 He_PIG PF05345.12 EKX47150.1 - 0.033 14.4 0.2 8.4 6.7 0.1 2.8 3 0 0 3 3 3 0 Putative Ig domain DUF4469 PF14734.6 EKX47150.1 - 0.056 13.6 0.0 4.8 7.4 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4469) with IG-like fold MORN PF02493.20 EKX47152.1 - 9.1e-34 113.3 67.4 2.8e-06 26.9 0.3 10.0 10 0 0 10 10 10 8 MORN repeat Ribo_biogen_C PF04034.13 EKX47153.1 - 1.7e-50 170.0 0.0 2.1e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EKX47153.1 - 9e-12 44.6 0.1 1.6e-11 43.8 0.1 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Prefoldin_2 PF01920.20 EKX47154.1 - 0.0063 16.5 2.3 0.012 15.6 2.3 1.4 1 0 0 1 1 1 1 Prefoldin subunit Rho_Binding PF08912.11 EKX47154.1 - 0.029 15.2 0.6 0.052 14.4 0.6 1.4 1 0 0 1 1 1 0 Rho Binding CENP-Q PF13094.6 EKX47154.1 - 0.091 13.0 3.1 0.14 12.4 3.1 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit NBP1 PF08537.10 EKX47154.1 - 0.12 11.8 1.8 0.17 11.3 1.8 1.1 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 XG_FTase PF03254.13 EKX47155.1 - 6e-05 21.9 0.0 0.00028 19.6 0.0 1.9 2 0 0 2 2 2 1 Xyloglucan fucosyltransferase Ank_2 PF12796.7 EKX47156.1 - 3.6e-66 219.7 3.2 4.5e-11 43.2 0.0 8.3 3 2 4 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX47156.1 - 7.3e-53 176.3 15.0 9.1e-10 38.9 0.0 11.0 7 3 4 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX47156.1 - 5.4e-40 130.8 10.5 0.00081 19.7 0.0 14.5 14 0 0 14 14 14 7 Ankyrin repeat Ank_5 PF13857.6 EKX47156.1 - 2e-35 120.4 18.6 1.8e-05 24.9 0.1 13.0 6 5 7 13 13 13 10 Ankyrin repeats (many copies) Ank PF00023.30 EKX47156.1 - 4.5e-35 118.6 11.3 0.0016 18.8 0.0 13.6 15 0 0 15 15 14 8 Ankyrin repeat ART PF01129.18 EKX47156.1 - 1.8e-11 43.7 0.0 3.9e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase EF-hand_6 PF13405.6 EKX47156.1 - 6.6e-09 35.0 5.4 0.0003 20.5 0.3 2.8 2 0 0 2 2 2 2 EF-hand domain ADPrib_exo_Tox PF03496.14 EKX47156.1 - 1.7e-08 34.0 0.0 6.2e-08 32.2 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosyltransferase exoenzyme EF-hand_1 PF00036.32 EKX47156.1 - 2.1e-08 33.1 6.8 2e-05 23.8 0.4 2.7 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EKX47156.1 - 8.9e-08 31.3 7.4 8.5e-05 21.9 0.5 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX47156.1 - 2e-07 31.4 2.2 5.6e-07 29.9 1.8 2.0 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EKX47156.1 - 0.01 15.6 1.1 0.23 11.3 0.1 2.6 1 1 1 2 2 2 0 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX47156.1 - 0.021 15.2 0.4 0.073 13.4 0.4 1.9 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region RRM_1 PF00076.22 EKX47159.1 - 5.7e-19 67.7 0.0 9.4e-19 67.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA-synt_2 PF00152.20 EKX47161.1 - 5.5e-82 275.3 0.0 7e-82 275.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 EKX47161.1 - 1.8e-07 30.9 0.1 0.0042 16.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 EKX47161.1 - 6.3e-05 22.9 0.2 0.22 11.5 0.0 2.4 1 1 1 2 2 2 2 OB-fold nucleic acid binding domain GSH-S_ATP PF02955.16 EKX47161.1 - 0.17 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain MORN PF02493.20 EKX47162.1 - 1e-29 100.6 42.9 5.6e-07 29.1 0.2 8.6 8 0 0 8 8 8 8 MORN repeat EII-Sor PF03609.14 EKX47162.1 - 0.0065 15.9 3.6 0.0098 15.3 3.6 1.1 1 0 0 1 1 1 1 PTS system sorbose-specific iic component PrgI PF12666.7 EKX47162.1 - 1.7 9.4 5.9 3.2 8.5 5.9 1.3 1 0 0 1 1 1 0 PrgI family protein Menin PF05053.13 EKX47162.1 - 2.2 6.6 7.4 3.5 5.9 7.4 1.2 1 0 0 1 1 1 0 Menin Stevor PF17410.2 EKX47162.1 - 5.9 6.3 4.6 9.3 5.7 4.6 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame zf-met2 PF12907.7 EKX47163.1 - 0.024 14.8 1.1 0.045 13.9 0.2 1.8 2 0 0 2 2 2 0 Zinc-binding Peptidase_S8 PF00082.22 EKX47165.1 - 1e-38 133.3 4.2 7.2e-21 74.7 0.0 2.9 3 0 0 3 3 3 2 Subtilase family DUF4215 PF13948.6 EKX47165.1 - 3.8e-13 49.6 37.9 1.4e-07 31.8 11.0 6.4 7 1 1 8 8 8 3 Domain of unknown function (DUF4215) PA PF02225.22 EKX47165.1 - 7.5e-05 22.7 0.0 0.00033 20.6 0.0 2.1 2 0 0 2 2 2 1 PA domain PPC PF04151.15 EKX47165.1 - 0.00011 23.3 0.4 0.00068 20.7 0.4 2.6 1 0 0 1 1 1 1 Bacterial pre-peptidase C-terminal domain hEGF PF12661.7 EKX47165.1 - 0.38 11.5 8.9 0.27 11.9 4.9 3.1 2 0 0 2 2 2 0 Human growth factor-like EGF zf-C3HC4 PF00097.25 EKX47167.1 - 9.7e-09 35.0 6.0 1.8e-08 34.1 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EKX47167.1 - 1.5e-07 31.2 8.9 3.1e-07 30.2 8.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX47167.1 - 3.5e-07 30.1 8.2 7.4e-07 29.0 8.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EKX47167.1 - 6.2e-07 29.6 7.1 1.3e-06 28.6 7.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EKX47167.1 - 3.3e-06 27.0 4.5 3.3e-06 27.0 4.5 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EKX47167.1 - 2.1e-05 24.3 7.4 4.3e-05 23.3 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX47167.1 - 0.001 18.9 6.6 0.0024 17.7 5.8 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EKX47167.1 - 0.0054 16.9 8.9 0.017 15.3 8.9 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF3797 PF12677.7 EKX47167.1 - 0.15 12.0 0.9 2.6 8.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) zf-rbx1 PF12678.7 EKX47167.1 - 2.3 8.6 7.0 6.4 7.1 7.0 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain Chorismate_synt PF01264.21 EKX47168.1 - 7.5e-143 475.1 0.7 9.1e-143 474.9 0.7 1.1 1 0 0 1 1 1 1 Chorismate synthase TPR_16 PF13432.6 EKX47169.1 - 7e-31 106.6 5.3 0.00021 21.8 0.4 10.7 9 2 2 11 11 11 7 Tetratricopeptide repeat TPR_19 PF14559.6 EKX47169.1 - 4.1e-29 100.9 11.1 7.7e-05 23.1 0.0 8.8 6 1 3 9 9 8 7 Tetratricopeptide repeat TPR_14 PF13428.6 EKX47169.1 - 4.8e-28 95.4 17.7 0.011 16.5 0.0 13.3 5 4 9 14 14 13 5 Tetratricopeptide repeat TPR_17 PF13431.6 EKX47169.1 - 2.9e-27 93.0 13.7 0.015 15.6 0.2 13.6 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_2 PF07719.17 EKX47169.1 - 3.8e-27 92.2 14.5 0.00073 19.5 0.4 13.3 14 0 0 14 14 13 6 Tetratricopeptide repeat TPR_11 PF13414.6 EKX47169.1 - 1.7e-26 91.6 7.3 5e-06 26.1 0.2 10.5 8 3 3 11 11 11 4 TPR repeat TPR_1 PF00515.28 EKX47169.1 - 4.3e-23 80.1 13.2 0.00097 18.9 1.3 13.7 15 1 0 15 15 15 4 Tetratricopeptide repeat TPR_8 PF13181.6 EKX47169.1 - 1.4e-21 74.8 8.2 0.00041 20.3 0.2 12.5 14 0 0 14 14 13 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX47169.1 - 1.2e-17 62.5 6.7 0.00058 19.7 0.1 9.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX47169.1 - 3.1e-13 49.8 17.5 0.028 14.7 0.1 8.4 6 2 3 9 9 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX47169.1 - 7e-09 35.8 6.3 0.82 9.9 0.0 6.4 5 1 2 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EKX47169.1 - 1.2e-08 35.0 4.4 1.9 9.3 0.2 8.8 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX47169.1 - 3e-06 26.9 16.0 0.021 14.7 0.0 7.3 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX47169.1 - 7e-06 26.1 6.9 22 5.3 0.0 7.7 6 4 4 10 10 10 0 Tetratricopeptide repeat Coatomer_E PF04733.14 EKX47169.1 - 0.00013 21.5 14.4 1.2 8.4 0.1 6.0 4 2 1 5 5 5 2 Coatomer epsilon subunit Alkyl_sulf_dimr PF14863.6 EKX47169.1 - 0.0014 19.1 0.6 1.9 8.9 0.1 4.1 3 0 0 3 3 3 1 Alkyl sulfatase dimerisation PPR PF01535.20 EKX47169.1 - 0.0035 17.5 0.5 19 5.8 0.0 5.0 5 0 0 5 5 4 0 PPR repeat DUF627 PF04781.12 EKX47169.1 - 0.0077 16.2 0.2 8.6 6.4 0.0 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF627) DUF4919 PF16266.5 EKX47169.1 - 0.012 15.5 1.2 8.4 6.3 0.0 3.7 4 0 0 4 4 3 0 Domain of unknown function (DUF4919) TPR_3 PF07720.12 EKX47169.1 - 0.018 15.0 4.8 12 6.1 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPPII_N PF12583.8 EKX47169.1 - 0.037 14.6 0.8 40 4.8 0.0 4.8 4 1 1 5 5 5 0 Tripeptidyl peptidase II N terminal Sel1 PF08238.12 EKX47169.1 - 0.057 14.1 7.8 2.8 8.8 0.4 4.4 4 0 0 4 4 2 0 Sel1 repeat Tcf25 PF04910.14 EKX47169.1 - 0.14 11.2 3.5 2.6 7.0 0.0 3.5 4 0 0 4 4 4 0 Transcriptional repressor TCF25 Peptidase_U57 PF05582.12 EKX47169.1 - 1.7 7.8 5.8 4.2 6.5 2.3 2.2 2 0 0 2 2 2 0 YabG peptidase U57 DUF1682 PF07946.14 EKX47169.1 - 9.7 5.3 13.3 18 4.4 13.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF775 PF05603.12 EKX47170.1 - 1.1e-25 90.3 0.1 5.2e-24 84.9 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF775) Reovirus_M2 PF05993.12 EKX47170.1 - 0.16 10.0 0.0 0.21 9.7 0.0 1.1 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Rcd1 PF04078.13 EKX47171.1 - 1.8e-127 424.0 0.9 2.1e-127 423.8 0.9 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Ion_trans_2 PF07885.16 EKX47172.1 - 3.1e-11 43.1 19.6 1.2e-08 34.7 0.9 3.2 3 0 0 3 3 3 2 Ion channel SK_channel PF03530.14 EKX47172.1 - 1e-05 25.5 2.2 0.00035 20.6 0.2 3.2 3 0 0 3 3 3 1 Calcium-activated SK potassium channel Ion_trans PF00520.31 EKX47172.1 - 1.6e-05 24.3 20.8 1.9e-05 24.0 5.9 2.6 2 1 0 2 2 2 2 Ion transport protein Lig_chan PF00060.26 EKX47172.1 - 2.1e-05 24.4 7.0 0.041 13.7 2.1 2.6 2 0 0 2 2 2 2 Ligand-gated ion channel Synaptobrevin PF00957.21 EKX47172.1 - 0.28 11.0 2.3 8.8 6.2 0.1 3.9 3 0 0 3 3 3 0 Synaptobrevin DUF334 PF03904.13 EKX47172.1 - 0.92 9.0 4.3 0.89 9.0 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF334) YqhR PF11085.8 EKX47172.1 - 1.7 8.6 8.8 1.9 8.4 0.4 3.4 4 0 0 4 4 4 0 Conserved membrane protein YqhR DUF1279 PF06916.13 EKX47173.1 - 7.9e-25 87.2 0.1 1.6e-24 86.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) ECH_1 PF00378.20 EKX47174.1 - 1.7e-40 138.9 0.0 3.1e-40 138.1 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EKX47174.1 - 2e-33 116.3 0.0 2.7e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase PIN_8 PF18476.1 EKX47175.1 - 0.00094 19.1 3.8 0.0012 18.8 3.8 1.2 1 0 0 1 1 1 1 PIN like domain DUF4510 PF14971.6 EKX47175.1 - 0.0028 18.0 3.0 0.012 16.0 3.2 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4510) Apolipoprotein PF01442.18 EKX47175.1 - 0.0073 16.2 12.5 0.011 15.7 12.5 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Prominin PF05478.11 EKX47175.1 - 0.0075 14.3 5.7 0.009 14.0 5.7 1.0 1 0 0 1 1 1 1 Prominin Atg14 PF10186.9 EKX47175.1 - 0.014 14.5 7.7 0.017 14.2 7.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 EKX47175.1 - 0.033 13.4 10.3 0.039 13.2 10.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein TolB_N PF04052.13 EKX47175.1 - 0.042 14.0 0.3 0.065 13.4 0.3 1.4 1 0 0 1 1 1 0 TolB amino-terminal domain Exonuc_VII_L PF02601.15 EKX47175.1 - 0.047 13.3 4.5 0.051 13.2 4.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FRB_dom PF08771.11 EKX47175.1 - 0.061 13.7 6.6 3 8.3 6.6 2.1 1 1 0 1 1 1 0 FKBP12-rapamycin binding domain DUF1043 PF06295.12 EKX47175.1 - 0.065 13.2 8.5 0.085 12.9 8.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) BshC PF10079.9 EKX47175.1 - 0.1 11.4 7.6 0.13 11.0 7.6 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC Het-C PF07217.11 EKX47175.1 - 0.11 11.0 2.9 0.15 10.6 2.9 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C FlpD PF02662.16 EKX47175.1 - 0.13 12.3 3.4 0.087 12.8 1.8 1.5 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit DUF1962 PF09227.10 EKX47175.1 - 0.22 11.9 0.1 0.4 11.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1962) PI3K_P85_iSH2 PF16454.5 EKX47175.1 - 0.28 10.8 15.3 0.44 10.1 15.3 1.4 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain LLC1 PF14945.6 EKX47175.1 - 0.36 11.4 4.2 0.22 12.1 1.0 2.0 1 1 1 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein BLOC1_2 PF10046.9 EKX47175.1 - 1.1 9.6 14.4 5.7 7.3 4.0 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CemA PF03040.14 EKX47175.1 - 1.7 8.6 4.4 2.2 8.2 4.4 1.2 1 0 0 1 1 1 0 CemA family XhlA PF10779.9 EKX47175.1 - 2 8.7 8.7 3.8 7.8 2.7 2.5 1 1 1 2 2 2 0 Haemolysin XhlA FapA PF03961.13 EKX47175.1 - 4.4 5.8 9.9 5.8 5.4 9.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1690 PF07956.11 EKX47175.1 - 7.3 7.0 12.9 22 5.5 12.8 1.7 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) DEAD PF00270.29 EKX47176.1 - 1.4e-47 161.7 0.1 2.2e-47 161.1 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX47176.1 - 7e-25 87.5 0.0 3.3e-24 85.4 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EKX47176.1 - 2.4e-19 69.3 0.3 5e-19 68.3 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EKX47176.1 - 4.8e-10 39.7 0.3 1.7e-09 37.9 0.0 1.9 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EKX47176.1 - 0.019 15.2 0.2 0.099 12.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EKX47176.1 - 0.058 13.3 0.6 0.18 11.7 0.0 2.2 3 0 0 3 3 3 0 NACHT domain SecA_DEAD PF07517.14 EKX47176.1 - 0.18 11.1 2.3 0.98 8.6 2.4 2.0 1 1 0 1 1 1 0 SecA DEAD-like domain IMCp PF12314.8 EKX47177.1 - 0.29 11.4 40.3 0.062 13.6 10.8 3.2 1 1 2 3 3 3 0 Inner membrane complex protein DUF4850 PF16142.5 EKX47177.1 - 0.37 10.3 5.9 1.2 8.6 1.1 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4850) Collagen PF01391.18 EKX47178.1 - 1.9e-12 46.7 33.4 1.3e-06 28.1 33.4 2.2 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Drf_FH1 PF06346.12 EKX47178.1 - 0.34 10.6 17.4 0.41 10.4 17.4 1.1 1 0 0 1 1 1 0 Formin Homology Region 1 Pkinase_Tyr PF07714.17 EKX47179.1 - 1.8e-61 207.7 0.0 2.4e-61 207.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX47179.1 - 1.3e-55 188.6 0.0 1.9e-55 188.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain fn3 PF00041.21 EKX47179.1 - 6.4e-10 39.3 0.0 2.2e-05 24.7 0.0 2.7 2 0 0 2 2 2 2 Fibronectin type III domain APH PF01636.23 EKX47179.1 - 0.01 15.8 0.0 0.035 14.0 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family TILa PF12714.7 EKX47180.1 - 0.047 13.7 0.7 0.078 12.9 0.7 1.4 1 0 0 1 1 1 0 TILa domain RWP-RK PF02042.15 EKX47183.1 - 3.4e-16 58.9 0.1 6.5e-16 58.0 0.1 1.5 1 0 0 1 1 1 1 RWP-RK domain Myb_DNA-binding PF00249.31 EKX47184.1 - 1.3e-06 28.4 0.0 4.4e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 Myb-like DNA-binding domain SET PF00856.28 EKX47185.1 - 0.025 15.0 0.0 0.047 14.1 0.0 1.4 1 0 0 1 1 1 0 SET domain SulA PF03846.14 EKX47185.1 - 0.025 14.5 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Cell division inhibitor SulA EVC2_like PF12297.8 EKX47185.1 - 0.14 10.8 5.4 0.31 9.7 4.2 1.8 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein DNA_pol_B_palm PF14792.6 EKX47186.1 - 7.4e-23 80.9 0.1 1.1e-22 80.3 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 EKX47186.1 - 1.6e-16 60.2 0.0 3.6e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 EKX47186.1 - 6.4e-12 45.1 0.0 1.3e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda Cdd1 PF11731.8 EKX47186.1 - 0.00032 20.9 0.0 0.0047 17.1 0.0 2.2 2 0 0 2 2 2 1 Pathogenicity locus HHH_5 PF14520.6 EKX47186.1 - 0.001 19.6 0.1 0.0055 17.3 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 EKX47186.1 - 0.025 14.9 0.0 0.057 13.7 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain HHH_3 PF12836.7 EKX47186.1 - 0.054 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif IMS_HHH PF11798.8 EKX47186.1 - 0.12 12.7 0.0 0.37 11.2 0.0 1.9 1 0 0 1 1 1 0 IMS family HHH motif Ank_4 PF13637.6 EKX47187.1 - 1.4e-07 31.9 0.0 2.7e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX47187.1 - 3.2e-06 27.6 0.0 4.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX47187.1 - 0.0004 20.6 0.0 0.78 10.1 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX47187.1 - 0.0018 18.6 0.0 1.6 9.5 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EKX47187.1 - 0.026 14.9 0.0 3.7 8.2 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat LCAT PF02450.15 EKX47187.1 - 0.19 10.9 0.0 0.22 10.6 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF2828 PF11443.8 EKX47188.1 - 2e-42 145.1 0.0 2.4e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) VWA_CoxE PF05762.14 EKX47188.1 - 2.3e-07 30.5 0.0 3.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF2828 PF11443.8 EKX47189.1 - 3.5e-34 117.9 0.3 2.9e-28 98.3 0.4 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF2828) AAR2 PF05282.11 EKX47189.1 - 0.12 11.8 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 AAR2 protein FKBP_C PF00254.28 EKX47190.1 - 7.4e-32 109.5 0.0 1.1e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Hydantoinase_B PF02538.14 EKX47191.1 - 3.9e-167 556.8 2.9 5.7e-127 424.2 0.0 2.2 1 1 1 2 2 2 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EKX47191.1 - 4.8e-97 324.7 0.0 1.1e-96 323.6 0.0 1.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EKX47191.1 - 2.6e-60 203.2 0.5 9.3e-58 194.8 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Chromo PF00385.24 EKX47192.1 - 3e-12 46.3 0.2 5.3e-12 45.5 0.2 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 EKX47192.1 - 0.029 14.5 0.1 0.053 13.7 0.1 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 CDC45 PF02724.14 EKX47192.1 - 0.056 11.7 7.8 0.058 11.7 7.8 1.2 1 0 0 1 1 1 0 CDC45-like protein HR1 PF02185.16 EKX47194.1 - 0.084 13.0 0.5 0.084 13.0 0.5 3.3 2 1 1 3 3 3 0 Hr1 repeat Fib_alpha PF08702.10 EKX47194.1 - 0.34 11.1 10.5 3.5 7.8 5.5 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF641 PF04859.12 EKX47194.1 - 0.42 11.0 17.4 0.32 11.3 0.7 2.6 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) XLF PF09302.11 EKX47194.1 - 0.63 10.2 9.8 0.19 11.9 3.7 2.3 1 1 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component TMPIT PF07851.13 EKX47194.1 - 0.71 9.1 9.8 0.43 9.8 5.6 2.0 2 0 0 2 2 2 0 TMPIT-like protein DUF16 PF01519.16 EKX47194.1 - 1.1 9.8 9.4 13 6.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.12 EKX47194.1 - 1.8 9.2 15.7 0.097 13.3 2.4 4.2 3 2 2 5 5 5 0 SlyX UPF0242 PF06785.11 EKX47194.1 - 1.9 8.6 18.0 1.1 9.3 9.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus MPS2 PF17060.5 EKX47194.1 - 2.1 7.5 12.6 6.4 5.9 0.1 2.2 2 0 0 2 2 2 0 Monopolar spindle protein 2 DUF99 PF01949.16 EKX47194.1 - 2.4 7.5 5.4 2.4 7.5 2.7 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF99 APG6_N PF17675.1 EKX47194.1 - 2.6 8.6 22.5 6 7.4 12.7 2.4 2 1 0 2 2 2 0 Apg6 coiled-coil region Spc7 PF08317.11 EKX47194.1 - 3.8 6.3 17.1 9 5.1 0.4 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein CENP-H PF05837.12 EKX47194.1 - 4.2 7.8 17.8 0.76 10.2 7.7 2.6 2 1 0 2 2 2 0 Centromere protein H (CENP-H) ATG16 PF08614.11 EKX47194.1 - 5.1 7.3 27.9 4.1 7.6 15.6 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ADIP PF11559.8 EKX47194.1 - 6.4 6.8 18.8 2.8 8.0 1.0 2.8 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding KxDL PF10241.9 EKX47194.1 - 7.7 6.9 15.0 16 5.9 7.7 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein Med21 PF11221.8 EKX47194.1 - 8.2 6.7 17.9 32 4.8 17.1 2.3 1 1 1 2 2 2 0 Subunit 21 of Mediator complex PRP1_N PF06424.12 EKX47194.1 - 8.4 6.8 9.8 0.46 10.9 4.1 1.8 2 1 0 2 2 2 0 PRP1 splicing factor, N-terminal Pkinase PF00069.25 EKX47198.1 - 2.4e-43 148.4 0.0 3.3e-43 148.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX47198.1 - 2.1e-18 66.5 0.0 6e-18 65.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EKX47198.1 - 0.033 14.1 0.1 2 8.3 0.0 2.4 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EKX47198.1 - 0.034 13.5 0.0 0.081 12.3 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EKX47198.1 - 0.12 11.7 0.0 0.52 9.6 0.0 1.9 2 1 0 2 2 2 0 Kinase-like WW PF00397.26 EKX47199.1 - 3.7e-15 55.7 5.8 1e-09 38.3 1.6 3.4 4 0 0 4 4 4 2 WW domain Glyco_hyd_101C PF17451.2 EKX47199.1 - 0.0016 18.7 1.3 0.2 11.9 0.0 2.9 2 1 0 2 2 2 1 Glycosyl hydrolase 101 beta sandwich domain LPP PF04728.13 EKX47199.1 - 0.063 13.7 1.4 0.063 13.7 1.4 2.7 3 0 0 3 3 3 0 Lipoprotein leucine-zipper PRT_C PF08372.10 EKX47199.1 - 0.1 12.4 0.1 0.44 10.3 0.0 2.0 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal DUF2570 PF10828.8 EKX47199.1 - 0.43 10.4 7.1 0.43 10.4 4.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Latarcin PF10279.9 EKX47199.1 - 0.6 10.5 5.5 5.9 7.4 5.5 2.5 1 1 0 1 1 1 0 Latarcin precursor DUF4446 PF14584.6 EKX47199.1 - 0.71 9.8 12.7 0.97 9.4 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) UPF0242 PF06785.11 EKX47199.1 - 1.8 8.6 15.0 0.16 12.0 9.6 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus RP-C_C PF11800.8 EKX47199.1 - 2 8.5 11.1 0.36 10.9 6.9 1.9 2 0 0 2 2 2 0 Replication protein C C-terminal region NIBRIN_BRCT_II PF16508.5 EKX47199.1 - 2.2 8.6 4.6 1.3 9.4 0.8 2.4 1 1 1 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein Prominin PF05478.11 EKX47199.1 - 2.5 5.9 10.0 0.32 8.9 6.1 1.4 2 0 0 2 2 2 0 Prominin DUF3106 PF11304.8 EKX47199.1 - 2.7 8.5 12.2 1.6 9.3 7.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) LMBR1 PF04791.16 EKX47199.1 - 5.1 5.9 8.1 7.3 5.4 8.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein YabA PF06156.13 EKX47199.1 - 9 7.0 9.4 1.9 9.2 5.1 2.1 2 1 0 2 2 2 0 Initiation control protein YabA Peptidase_S8 PF00082.22 EKX47200.1 - 5e-07 29.3 0.8 0.00034 20.0 0.0 3.2 2 1 1 3 3 3 2 Subtilase family PA PF02225.22 EKX47200.1 - 3.2e-06 27.1 0.1 1.1e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 PA domain DUF4215 PF13948.6 EKX47200.1 - 7.5e-05 23.1 4.3 7.5e-05 23.1 4.3 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4215) Aft1_OSA PF11785.8 EKX47200.1 - 0.075 13.5 0.0 0.24 11.8 0.0 1.9 1 0 0 1 1 1 0 Aft1 osmotic stress response (OSM) domain ATG22 PF11700.8 EKX47203.1 - 1.5e-21 76.6 30.4 2.1e-18 66.2 30.4 2.1 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EKX47203.1 - 7.5e-06 25.1 53.0 0.00021 20.4 8.2 3.1 2 1 0 3 3 3 2 Major Facilitator Superfamily PetG PF02529.15 EKX47203.1 - 0.17 11.7 3.3 0.1 12.4 0.5 2.2 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 DUF5316 PF17247.2 EKX47203.1 - 5.5 7.1 0.0 5.5 7.1 0.0 4.5 5 0 0 5 5 5 0 Family of unknown function (DUF5316) RRN3 PF05327.11 EKX47206.1 - 5.2e-99 332.3 10.3 2.4e-98 330.1 10.3 1.7 1 1 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Peptidase_M16_C PF05193.21 EKX47207.1 - 3.8e-44 150.9 0.0 7.7e-21 74.9 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EKX47207.1 - 1.1e-17 64.5 0.2 2.2e-16 60.1 0.0 2.8 4 0 0 4 4 4 1 Insulinase (Peptidase family M16) Phage_TAC_7 PF10109.9 EKX47207.1 - 0.13 12.4 0.0 0.75 9.9 0.0 2.2 2 0 0 2 2 2 0 Phage tail assembly chaperone proteins, E, or 41 or 14 PH PF00169.29 EKX47208.1 - 9.5e-06 26.1 0.6 1.9e-05 25.1 0.6 1.5 1 0 0 1 1 1 1 PH domain ArsA_HSP20 PF17886.1 EKX47208.1 - 0.038 13.5 0.1 0.12 12.0 0.1 1.8 1 0 0 1 1 1 0 HSP20-like domain found in ArsA Med9 PF07544.13 EKX47208.1 - 0.15 12.2 0.3 0.38 10.9 0.3 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 PH_11 PF15413.6 EKX47208.1 - 0.17 12.3 1.4 1.3 9.5 0.6 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain INSIG PF07281.12 EKX47210.1 - 4.2e-11 42.9 1.9 1.1e-06 28.5 1.5 2.2 2 0 0 2 2 2 2 Insulin-induced protein (INSIG) DUF2632 PF10943.8 EKX47210.1 - 0.041 13.5 1.0 0.041 13.5 1.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2632) Myb_DNA-binding PF00249.31 EKX47211.1 - 0.0047 17.1 0.0 0.0096 16.1 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3110 PF11360.8 EKX47212.1 - 2.3e-29 101.4 0.0 2.5e-29 101.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3110) DUF4504 PF14953.6 EKX47213.1 - 1.9e-25 89.8 0.0 3.2e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4504) MORN PF02493.20 EKX47213.1 - 8.3e-06 25.4 13.7 0.00027 20.6 0.3 3.3 4 0 0 4 4 4 2 MORN repeat Tetraspanin PF00335.20 EKX47213.1 - 0.0066 16.2 4.2 0.012 15.4 4.2 1.4 1 0 0 1 1 1 1 Tetraspanin family Nucleotid_trans PF03407.16 EKX47214.1 - 2e-20 73.7 0.0 3.5e-20 72.9 0.0 1.3 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase YukD PF08817.10 EKX47215.1 - 0.0008 20.0 0.0 0.0018 18.9 0.0 1.5 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD UBX PF00789.20 EKX47215.1 - 0.025 14.8 0.0 0.058 13.6 0.0 1.6 1 0 0 1 1 1 0 UBX domain UN_NPL4 PF11543.8 EKX47215.1 - 0.042 14.3 0.0 0.38 11.3 0.0 2.3 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 BNIP3 PF06553.12 EKX47215.1 - 0.068 12.8 0.4 0.068 12.8 0.4 2.1 2 0 0 2 2 2 0 BNIP3 F-box PF00646.33 EKX47216.1 - 0.0024 17.7 0.1 0.0056 16.5 0.1 1.6 1 0 0 1 1 1 1 F-box domain PI31_Prot_N PF11566.8 EKX47216.1 - 0.044 13.6 0.0 0.092 12.5 0.0 1.5 1 1 0 1 1 1 0 PI31 proteasome regulator N-terminal PP2C PF00481.21 EKX47218.1 - 1.9e-33 116.2 0.0 3.2e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EKX47218.1 - 1.6e-07 31.2 0.0 3e-07 30.3 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C Chorein_N PF12624.7 EKX47219.1 - 6.9e-08 32.6 0.1 2.7e-07 30.7 0.1 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 FUSC PF04632.12 EKX47220.1 - 0.26 9.8 15.3 0.37 9.3 8.6 2.4 1 1 1 2 2 2 0 Fusaric acid resistance protein family Allexi_40kDa PF05549.11 EKX47220.1 - 0.95 8.9 22.7 0.34 10.4 3.7 3.6 1 1 2 3 3 3 0 Allexivirus 40kDa protein Baculo_PEP_C PF04513.12 EKX47220.1 - 1 9.4 13.5 1.5 8.8 0.2 4.1 1 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus SKA1 PF07160.12 EKX47220.1 - 4.3 7.1 36.4 0.37 10.6 14.0 3.5 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 1 CT_C_D PF02682.16 EKX47220.1 - 7.8 6.2 10.2 0.96 9.1 4.0 2.5 1 1 2 3 3 3 0 Carboxyltransferase domain, subdomain C and D Spc7 PF08317.11 EKX47220.1 - 8.2 5.2 52.8 0.13 11.2 11.4 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein AhpC-TSA PF00578.21 EKX47221.1 - 7.2e-20 71.2 0.0 8.5e-20 70.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EKX47221.1 - 5.6e-15 55.3 0.0 6.8e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 EKX47221.1 - 0.017 15.4 0.0 0.025 14.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Glutaredoxin PF00462.24 EKX47221.1 - 0.028 14.7 0.0 0.059 13.6 0.0 1.6 1 1 0 1 1 1 0 Glutaredoxin Thioredoxin_2 PF13098.6 EKX47221.1 - 0.039 14.4 0.0 0.057 13.9 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin PF00085.20 EKX47221.1 - 0.11 12.5 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin 2OG-FeII_Oxy_3 PF13640.6 EKX47222.1 - 3.6e-07 31.0 0.0 9.6e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_14 PF13428.6 EKX47222.1 - 0.054 14.3 0.0 0.22 12.4 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TauE PF01925.19 EKX47223.1 - 1.4e-43 149.2 26.6 2.3e-24 86.3 13.7 2.0 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE zf-C2H2_6 PF13912.6 EKX47223.1 - 0.35 10.9 1.1 0.89 9.6 0.2 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger Trypan_PARP PF05887.11 EKX47224.1 - 0.38 10.7 2.5 0.34 10.9 1.0 1.6 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) Zn_clus PF00172.18 EKX47226.1 - 3.8e-16 58.9 24.6 8.7e-09 35.4 6.0 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain NinD PF17466.2 EKX47228.1 - 0.026 14.6 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function Amidohydro_1 PF01979.20 EKX47229.1 - 1.7e-42 146.0 0.0 2.1e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EKX47229.1 - 5.6e-13 49.2 0.1 3e-06 27.0 0.0 2.2 1 1 0 2 2 2 2 Amidohydrolase family PrpR_N PF06506.11 EKX47229.1 - 0.17 11.4 0.0 6.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Propionate catabolism activator AhpC-TSA PF00578.21 EKX47230.1 - 7.2e-20 71.2 0.0 8.5e-20 70.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EKX47230.1 - 5.6e-15 55.3 0.0 6.8e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 EKX47230.1 - 0.017 15.4 0.0 0.025 14.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Glutaredoxin PF00462.24 EKX47230.1 - 0.027 14.7 0.0 0.059 13.6 0.0 1.7 1 1 0 1 1 1 0 Glutaredoxin Thioredoxin_2 PF13098.6 EKX47230.1 - 0.039 14.4 0.0 0.057 13.9 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin PF00085.20 EKX47230.1 - 0.11 12.5 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin Mre11_DNA_bind PF04152.14 EKX47231.1 - 4.2e-06 27.2 6.8 0.0014 19.0 0.1 2.9 2 1 1 3 3 3 2 Mre11 DNA-binding presumed domain Sigma_reg_C PF13791.6 EKX47231.1 - 0.0043 17.3 0.8 0.0089 16.2 0.8 1.5 1 0 0 1 1 1 1 Sigma factor regulator C-terminal Prok_Ub PF14454.6 EKX47231.1 - 0.04 13.6 0.0 0.085 12.5 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic Ubiquitin Metallophos PF00149.28 EKX47232.1 - 2.7e-08 34.6 0.1 4.4e-08 33.9 0.1 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EKX47232.1 - 0.0029 17.8 0.0 0.022 14.9 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF179 PF02622.15 EKX47233.1 - 6e-24 84.8 0.0 8.5e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 RWP-RK PF02042.15 EKX47234.1 - 7.2e-13 48.3 0.2 1e-12 47.8 0.2 1.2 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX47234.1 - 0.12 12.2 0.6 5.9 6.8 0.1 2.4 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family RWP-RK PF02042.15 EKX47235.1 - 7.2e-13 48.3 0.2 1e-12 47.8 0.2 1.2 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX47235.1 - 0.12 12.2 0.6 5.9 6.8 0.1 2.4 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family Kinesin PF00225.23 EKX47236.1 - 3.2e-30 105.2 0.2 3.9e-30 104.9 0.2 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX47236.1 - 1.8e-20 73.4 0.1 2.1e-20 73.1 0.1 1.0 1 0 0 1 1 1 1 Microtubule binding UCMA PF17085.5 EKX47236.1 - 0.12 12.4 0.4 3.8 7.5 0.2 2.1 1 1 1 2 2 2 0 Unique cartilage matrix associated protein AAA_24 PF13479.6 EKX47236.1 - 0.15 11.7 2.4 0.37 10.5 0.2 2.1 1 1 1 2 2 2 0 AAA domain Kinesin PF00225.23 EKX47237.1 - 2.3e-38 132.0 0.0 2.5e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Aminotran_3 PF00202.21 EKX47238.1 - 2.1e-112 375.8 0.0 2.4e-112 375.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 EKX47238.1 - 0.022 14.0 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase EF-hand_11 PF08976.11 EKX47239.1 - 0.11 13.4 0.0 0.4 11.6 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain Arm PF00514.23 EKX47240.1 - 8.5e-28 95.5 10.3 5.7e-05 23.0 0.0 11.2 13 0 0 13 13 13 6 Armadillo/beta-catenin-like repeat EDR1 PF14381.6 EKX47240.1 - 6e-25 88.1 0.1 1.6e-24 86.8 0.1 1.7 1 0 0 1 1 1 1 Ethylene-responsive protein kinase Le-CTR1 HEAT_2 PF13646.6 EKX47240.1 - 3.9e-11 43.2 12.4 0.05 14.0 0.3 7.0 3 2 3 7 7 7 4 HEAT repeats HEAT_EZ PF13513.6 EKX47240.1 - 1.8e-10 41.1 13.8 0.0035 17.8 0.1 7.7 7 2 1 8 8 8 3 HEAT-like repeat V-ATPase_H_N PF03224.14 EKX47240.1 - 0.0019 17.6 0.9 0.93 8.7 0.0 3.2 3 0 0 3 3 3 2 V-ATPase subunit H HEAT PF02985.22 EKX47240.1 - 0.0021 18.2 17.9 12 6.5 0.0 9.4 11 0 0 11 11 11 1 HEAT repeat Cnd1 PF12717.7 EKX47240.1 - 0.039 14.0 2.1 15 5.6 0.0 3.6 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.9 EKX47240.1 - 0.074 11.5 1.7 0.43 9.0 0.0 2.7 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit EMP24_GP25L PF01105.24 EKX47242.1 - 3.1e-43 147.8 0.0 3.5e-43 147.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 EKX47242.1 - 0.0068 16.6 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 SdrD B-like domain Ammonium_transp PF00909.21 EKX47244.1 - 6.9e-118 393.8 27.7 7.7e-118 393.6 27.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Ammonium_transp PF00909.21 EKX47245.1 - 7e-66 222.5 31.9 2e-50 171.6 23.4 2.0 2 0 0 2 2 2 2 Ammonium Transporter Family LYTB PF02401.18 EKX47246.1 - 2.2e-74 250.1 0.0 2.9e-74 249.7 0.0 1.1 1 0 0 1 1 1 1 LytB protein DSPn PF14671.6 EKX47250.1 - 2.9e-41 141.2 0.0 8.8e-41 139.6 0.0 1.8 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EKX47250.1 - 6.8e-13 48.6 0.1 7.4e-12 45.2 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX47250.1 - 3.7e-06 26.7 0.0 0.00019 21.1 0.0 2.2 1 1 1 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX47250.1 - 0.00095 19.3 0.0 0.0042 17.2 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EKX47250.1 - 0.04 13.9 0.0 0.061 13.3 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Methyltransf_11 PF08241.12 EKX47251.1 - 2e-11 44.4 0.0 4.6e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX47251.1 - 1.7e-07 31.8 0.0 4.3e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX47251.1 - 1.9e-06 27.8 0.0 4.1e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX47251.1 - 6.1e-06 26.1 0.0 1.5e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX47251.1 - 1.5e-05 25.7 0.5 5.5e-05 23.8 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_29 PF03141.16 EKX47251.1 - 0.0019 16.8 0.0 0.003 16.2 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.18 EKX47251.1 - 0.0047 16.3 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 EKX47251.1 - 0.0097 15.5 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Agenet PF05641.12 EKX47251.1 - 0.0099 16.3 0.6 0.026 15.0 0.6 1.8 1 0 0 1 1 1 1 Agenet domain N6_N4_Mtase PF01555.18 EKX47251.1 - 0.04 13.6 0.0 0.11 12.1 0.0 1.8 1 1 0 1 1 1 0 DNA methylase Clat_adaptor_s PF01217.20 EKX47252.1 - 1.5e-14 54.1 0.0 1.8e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Peptidase_S8 PF00082.22 EKX47253.1 - 3.1e-31 108.7 0.0 1.5e-30 106.5 0.0 2.2 1 1 0 1 1 1 1 Subtilase family PA PF02225.22 EKX47253.1 - 3.5e-10 39.8 0.5 8.9e-10 38.5 0.5 1.7 1 0 0 1 1 1 1 PA domain TM2 PF05154.16 EKX47253.1 - 8.4e-10 38.8 10.2 8.4e-10 38.8 10.2 2.1 2 0 0 2 2 2 1 TM2 domain PPC PF04151.15 EKX47253.1 - 0.051 14.7 0.3 0.051 14.7 0.3 2.7 3 0 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain ARPC4 PF05856.12 EKX47254.1 - 6.1e-69 230.9 4.3 6.8e-69 230.7 4.3 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) SARS_3b PF12383.8 EKX47254.1 - 0.062 13.4 0.3 0.12 12.5 0.1 1.4 1 1 0 1 1 1 0 Severe acute respiratory syndrome coronavirus 3b protein DUF1772 PF08592.11 EKX47256.1 - 0.085 13.2 0.0 0.093 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) TAN PF11640.8 EKX47257.1 - 0.005 17.0 4.1 0.011 15.9 4.1 1.5 1 1 0 1 1 1 1 Telomere-length maintenance and DNA damage repair DUF1539 PF07560.11 EKX47257.1 - 0.0094 16.0 0.3 0.025 14.6 0.1 1.7 1 1 1 2 2 2 1 Domain of Unknown Function (DUF1539) CAS_C PF12026.8 EKX47257.1 - 0.029 14.4 3.6 0.047 13.8 3.6 1.3 1 0 0 1 1 1 0 Crk-Associated Substrate C-terminal domain Med29 PF11568.8 EKX47257.1 - 0.039 14.2 1.5 0.068 13.4 1.5 1.5 1 0 0 1 1 1 0 Mediator complex subunit 29 DUF4551 PF15087.6 EKX47257.1 - 0.13 11.1 4.5 0.16 10.7 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Cluap1 PF10234.9 EKX47257.1 - 0.43 9.9 6.5 0.57 9.5 6.5 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 QRPTase_N PF02749.16 EKX47258.1 - 2.3e-07 30.7 19.1 25 5.0 0.1 8.9 1 1 14 15 15 15 4 Quinolinate phosphoribosyl transferase, N-terminal domain Asp_protease_2 PF13650.6 EKX47258.1 - 5e-05 23.9 6.5 17 6.1 0.0 5.7 1 1 2 3 3 3 3 Aspartyl protease LAX PF15681.5 EKX47258.1 - 0.43 9.4 41.6 4.7 5.9 7.2 4.4 1 1 2 4 4 4 0 Lymphocyte activation family X Snf7 PF03357.21 EKX47258.1 - 4.1 7.0 65.0 11 5.6 5.0 5.7 1 1 4 5 5 5 0 Snf7 Bac_rhodopsin PF01036.18 EKX47260.1 - 7.8e-35 120.5 18.0 1.1e-34 120.0 18.0 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein TctB PF07331.11 EKX47260.1 - 0.041 14.2 0.4 0.041 14.2 0.4 2.8 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family ATP_synt_H PF05493.13 EKX47260.1 - 0.076 13.5 0.7 0.076 13.5 0.7 2.9 2 1 0 2 2 2 0 ATP synthase subunit H DUF4131 PF13567.6 EKX47260.1 - 0.13 12.0 7.6 1.2 8.8 2.5 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) FixQ PF05545.11 EKX47260.1 - 0.2 11.7 0.0 0.2 11.7 0.0 4.2 4 1 1 5 5 5 0 Cbb3-type cytochrome oxidase component FixQ Polysacc_synt_C PF14667.6 EKX47260.1 - 0.42 10.7 14.9 0.61 10.1 0.5 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain DUF21 PF01595.20 EKX47260.1 - 0.48 10.1 8.9 1.4 8.6 8.8 1.9 1 1 0 1 1 1 0 Cyclin M transmembrane N-terminal domain DUF4199 PF13858.6 EKX47260.1 - 0.78 10.1 13.4 2 8.8 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF2070 PF09843.9 EKX47260.1 - 0.98 7.6 12.5 0.38 9.0 9.9 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) FeoB_associated PF12669.7 EKX47260.1 - 4.2 7.9 0.0 4.2 7.9 0.0 3.6 5 0 0 5 5 5 0 FeoB-associated Cys-rich membrane protein Pkinase PF00069.25 EKX47261.1 - 7.9e-58 195.9 0.0 3e-57 194.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX47261.1 - 3.9e-29 101.7 0.1 1.6e-28 99.7 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX47261.1 - 2.5e-05 23.7 0.1 0.0025 17.2 0.0 2.9 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 EKX47261.1 - 0.011 15.6 0.4 0.044 13.7 0.2 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EKX47261.1 - 0.013 14.5 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FAD_binding_2 PF00890.24 EKX47261.1 - 0.037 13.1 0.0 0.11 11.5 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Pkinase_fungal PF17667.1 EKX47261.1 - 0.038 12.8 0.0 0.098 11.4 0.0 1.5 1 1 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 EKX47261.1 - 0.071 12.7 0.0 3.8 7.1 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 NRDE-2 PF08424.10 EKX47262.1 - 3.6e-10 39.5 2.9 0.021 14.0 0.0 3.2 1 1 2 3 3 3 3 NRDE-2, necessary for RNA interference TPR_19 PF14559.6 EKX47262.1 - 9.2e-08 32.5 0.0 0.36 11.4 0.0 4.1 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 EKX47262.1 - 4.5e-06 26.1 0.2 0.00033 20.0 0.0 2.9 1 1 0 2 2 2 1 Tetratricopeptide repeat Suf PF05843.14 EKX47262.1 - 5.6e-06 26.5 9.7 0.013 15.5 0.2 3.8 3 1 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EKX47262.1 - 8.1e-05 23.1 3.6 1.7 9.6 0.0 4.8 4 2 1 5 5 5 2 Tetratricopeptide repeat TMEM214 PF10151.9 EKX47262.1 - 0.006 15.1 1.0 0.009 14.5 1.0 1.2 1 0 0 1 1 1 1 TMEM214, C-terminal, caspase 4 activator TPR_2 PF07719.17 EKX47262.1 - 0.1 12.7 3.6 12 6.3 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat S1 PF00575.23 EKX47263.1 - 9.7e-84 275.8 32.4 3.3e-15 56.2 0.6 14.1 14 0 0 14 14 14 12 S1 RNA binding domain PCB_OB PF17092.5 EKX47263.1 - 0.00054 20.7 7.4 22 5.9 0.0 7.8 6 3 0 7 7 7 2 Penicillin-binding protein OB-like domain S1_2 PF13509.6 EKX47263.1 - 0.00087 19.3 0.2 12 6.1 0.0 6.2 6 0 0 6 6 6 1 S1 domain RNase_II_C_S1 PF18614.1 EKX47263.1 - 3.2 7.8 20.0 11 6.1 0.1 8.3 9 1 0 9 9 9 0 RNase II-type exonuclease C-terminal S1 domain EF-hand_7 PF13499.6 EKX47264.1 - 9.4e-07 29.2 0.3 4.6e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair CorA PF01544.18 EKX47264.1 - 1.4e-06 27.9 1.5 1.6e-06 27.7 0.2 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein EF-hand_8 PF13833.6 EKX47264.1 - 0.00025 20.8 0.1 0.00051 19.8 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair DUF2721 PF11026.8 EKX47264.1 - 0.037 13.9 1.1 0.085 12.7 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) EF-hand_6 PF13405.6 EKX47264.1 - 0.07 13.1 1.1 6 7.1 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 EKX47264.1 - 0.093 12.3 1.0 15 5.4 0.0 3.3 3 0 0 3 3 3 0 EF hand PX PF00787.24 EKX47265.1 - 2.8e-17 62.7 0.0 4.3e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 PX domain TPR_12 PF13424.6 EKX47265.1 - 1.2e-12 47.9 10.0 5e-06 26.7 2.0 3.8 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX47265.1 - 1.3e-08 34.4 0.4 0.46 10.8 0.4 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX47265.1 - 4.8e-07 29.4 4.4 0.78 10.0 1.6 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX47265.1 - 9.8e-05 22.0 2.7 4.1 7.4 0.0 4.3 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX47265.1 - 0.0006 19.6 8.6 0.097 12.6 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX47265.1 - 0.002 18.1 7.3 0.52 10.5 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX47265.1 - 0.034 13.5 7.3 0.038 13.4 1.0 2.2 1 1 1 2 2 2 0 MalT-like TPR region TPR_17 PF13431.6 EKX47265.1 - 0.23 11.9 1.2 22 5.7 0.0 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EKX47265.1 - 0.35 11.6 4.2 7.4 7.5 0.6 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX47265.1 - 1.9 9.5 6.1 60 4.9 0.1 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX47266.1 - 0.042 14.1 1.3 0.053 13.8 0.3 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_31 PF13614.6 EKX47269.1 - 9.5e-23 81.0 0.0 1.6e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EKX47269.1 - 1.3e-13 51.2 0.0 1.8e-13 50.6 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 EKX47269.1 - 0.0002 20.9 0.0 0.00034 20.2 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 EKX47269.1 - 0.00024 20.5 0.0 0.0062 15.8 0.0 2.2 2 0 0 2 2 2 1 ATPase MipZ ParA PF10609.9 EKX47269.1 - 0.00043 19.8 0.0 0.0013 18.3 0.0 1.7 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 EKX47269.1 - 0.0012 18.4 0.0 0.079 12.4 0.0 2.3 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 EKX47269.1 - 0.0049 16.1 0.0 0.043 13.0 0.0 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase SRP54 PF00448.22 EKX47269.1 - 0.014 15.0 0.0 0.068 12.8 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Caudal_act PF04731.12 EKX47269.1 - 0.062 13.7 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Caudal like protein activation region AAA_25 PF13481.6 EKX47269.1 - 0.1 12.1 0.0 0.29 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain PRK PF00485.18 EKX47269.1 - 0.11 12.2 0.0 0.56 9.9 0.0 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family LpxK PF02606.14 EKX47269.1 - 0.15 11.1 0.1 0.61 9.1 0.0 1.9 2 0 0 2 2 2 0 Tetraacyldisaccharide-1-P 4'-kinase DUF676 PF05057.14 EKX47270.1 - 3.5e-05 23.4 0.0 0.015 14.8 0.0 2.2 2 0 0 2 2 2 2 Putative serine esterase (DUF676) FoP_duplication PF13865.6 EKX47270.1 - 0.12 12.9 6.4 0.2 12.3 6.4 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Cytomega_UL84 PF06284.11 EKX47270.1 - 0.16 10.4 2.2 0.28 9.6 2.2 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein TrmO PF01980.16 EKX47271.1 - 1.5e-18 67.2 1.0 5.7e-09 36.2 1.6 2.5 1 1 1 2 2 2 2 tRNA-methyltransferase O PseudoU_synth_2 PF00849.22 EKX47271.1 - 1.3e-16 61.1 0.0 2.2e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase TrmO_C PF18389.1 EKX47271.1 - 0.00012 22.1 0.0 0.0003 20.8 0.0 1.7 1 0 0 1 1 1 1 TrmO C-terminal domain PDZ_6 PF17820.1 EKX47275.1 - 4.6e-07 29.6 0.0 7.3e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX47275.1 - 1.5e-05 25.2 0.0 2.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX47275.1 - 9.3e-05 22.7 0.0 0.00014 22.1 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Nas2_N PF18265.1 EKX47276.1 - 1.1 9.2 5.5 36 4.4 0.0 3.4 3 0 0 3 3 3 0 Nas2 N_terminal domain DegS PF05384.11 EKX47276.1 - 1.2 8.6 8.3 0.12 11.9 1.9 2.5 3 0 0 3 3 3 0 Sensor protein DegS V-ATPase_G_2 PF16999.5 EKX47276.1 - 2.2 8.7 7.6 13 6.3 7.4 2.4 2 1 1 3 3 3 0 Vacuolar (H+)-ATPase G subunit TPR_12 PF13424.6 EKX47277.1 - 3.6e-21 75.2 4.6 1.9e-13 50.5 0.0 6.0 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX47277.1 - 7.6e-12 44.7 9.0 0.00027 20.7 0.0 6.2 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX47277.1 - 8.2e-11 41.3 16.6 5.2e-05 22.9 0.1 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX47277.1 - 4.5e-09 35.7 15.8 0.0017 18.3 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX47277.1 - 6.7e-08 32.1 13.4 0.0002 21.0 1.0 5.3 4 1 0 4 4 4 2 TPR repeat TPR_8 PF13181.6 EKX47277.1 - 2.2e-06 27.4 14.5 0.0016 18.5 0.1 5.9 6 1 0 6 6 5 1 Tetratricopeptide repeat MIT PF04212.18 EKX47277.1 - 1.7e-05 24.8 5.7 2.4 8.3 0.0 4.4 2 1 2 4 4 4 2 MIT (microtubule interacting and transport) domain TPR_17 PF13431.6 EKX47277.1 - 1.8e-05 24.8 1.2 0.97 10.0 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX47277.1 - 3.4e-05 23.6 2.6 1.2 9.3 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX47277.1 - 0.00015 22.3 1.4 2.3 9.2 0.0 4.7 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX47277.1 - 0.00025 21.5 3.5 0.002 18.6 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat DUF3856 PF12968.7 EKX47277.1 - 0.00077 19.6 0.6 0.069 13.2 0.1 3.3 2 1 0 2 2 2 1 Domain of Unknown Function (DUF3856) DUF5113 PF17140.4 EKX47277.1 - 0.012 15.5 1.1 6.4 6.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5113) DUF357 PF04010.13 EKX47277.1 - 0.017 15.2 0.1 0.8 9.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF357) DUF5388 PF17363.2 EKX47277.1 - 0.033 14.4 0.3 0.084 13.1 0.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5388) TPR_16 PF13432.6 EKX47277.1 - 0.039 14.6 5.7 1.5 9.5 0.2 3.9 4 1 0 4 4 3 0 Tetratricopeptide repeat DUF4885 PF16226.5 EKX47277.1 - 0.1 11.6 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4885) Nif11 PF07862.11 EKX47277.1 - 0.12 12.7 0.1 0.28 11.5 0.1 1.7 1 0 0 1 1 1 0 Nif11 domain PPR PF01535.20 EKX47277.1 - 0.25 11.7 1.4 19 5.8 0.0 4.0 4 0 0 4 4 4 0 PPR repeat SAM_1 PF00536.30 EKX47278.1 - 0.0057 17.1 1.6 0.38 11.2 0.0 3.1 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 EKX47278.1 - 0.036 14.0 0.5 4.4 7.4 0.1 2.3 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain Ion_trans_2 PF07885.16 EKX47278.1 - 0.15 12.1 0.2 0.15 12.1 0.2 2.1 2 0 0 2 2 2 0 Ion channel HEAT PF02985.22 EKX47279.1 - 3.6e-12 45.4 14.5 0.69 10.3 0.0 9.6 10 0 0 10 10 10 4 HEAT repeat Vac14_Fab1_bd PF12755.7 EKX47279.1 - 1.2e-07 32.2 2.7 0.12 13.0 0.2 5.7 4 2 1 6 6 6 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EKX47279.1 - 4.3e-07 30.1 3.2 0.0073 16.4 0.0 5.1 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EKX47279.1 - 2.2e-06 28.0 4.2 0.11 12.9 0.0 6.0 4 3 1 5 5 5 3 HEAT repeats HEAT_EZ PF13513.6 EKX47279.1 - 1.4e-05 25.5 9.5 0.023 15.2 0.0 7.2 9 0 0 9 9 9 1 HEAT-like repeat CLASP_N PF12348.8 EKX47279.1 - 0.00046 19.8 3.3 0.49 9.9 0.0 5.2 4 1 2 6 6 6 1 CLASP N terminal Adaptin_N PF01602.20 EKX47279.1 - 0.0049 15.5 5.0 0.27 9.8 0.2 3.9 5 0 0 5 5 5 2 Adaptin N terminal region Condensin2nSMC PF12422.8 EKX47279.1 - 0.095 12.9 0.1 2.2 8.5 0.0 3.1 3 0 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit V-ATPase_H_C PF11698.8 EKX47279.1 - 0.11 12.6 0.2 25 5.0 0.0 3.5 3 0 0 3 3 3 0 V-ATPase subunit H FA_FANCE PF11510.8 EKX47280.1 - 6e-13 48.8 1.5 2.1e-11 43.7 1.2 2.4 1 1 0 1 1 1 1 Fanconi Anaemia group E protein FANCE H_PPase PF03030.16 EKX47281.1 - 1.5e-259 863.1 35.6 1.8e-259 862.8 35.6 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase 2OG-FeII_Oxy_3 PF13640.6 EKX47282.1 - 3e-06 28.0 0.0 5.2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EKX47282.1 - 0.0035 17.8 0.0 0.0056 17.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Collagen PF01391.18 EKX47283.1 - 2.5e-19 68.8 71.3 4.6e-10 39.1 25.6 3.1 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) MORN PF02493.20 EKX47284.1 - 4.6e-42 139.4 45.6 2.6e-07 30.1 0.5 8.8 9 0 0 9 9 9 8 MORN repeat DUF2207 PF09972.9 EKX47286.1 - 0.012 14.4 0.7 0.015 14.1 0.0 1.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Methyltr_RsmB-F PF01189.17 EKX47288.1 - 4.5e-51 173.4 0.0 7e-51 172.7 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F NusB PF01029.18 EKX47288.1 - 1e-19 71.1 0.0 2e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 NusB family FtsJ PF01728.19 EKX47288.1 - 4.4e-07 30.2 0.0 7.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 EKX47288.1 - 1.4e-05 25.0 0.0 2.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmF_N PF17125.5 EKX47288.1 - 9.6e-05 22.8 0.0 0.00022 21.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Ubie_methyltran PF01209.18 EKX47288.1 - 0.0039 16.6 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EKX47288.1 - 0.0064 17.2 0.0 0.018 15.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EKX47288.1 - 0.033 13.8 0.0 0.057 13.0 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain N6_Mtase PF02384.16 EKX47288.1 - 0.13 11.5 0.0 0.51 9.5 0.0 1.9 1 1 0 1 1 1 0 N-6 DNA Methylase UCH PF00443.29 EKX47289.1 - 1.6e-24 86.8 0.0 4.3e-23 82.1 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EKX47289.1 - 1.3e-07 31.6 0.1 0.0038 16.9 0.1 2.2 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-HIT PF04438.16 EKX47289.1 - 0.05 13.5 0.2 0.13 12.2 0.2 1.7 1 0 0 1 1 1 0 HIT zinc finger tRNA_lig_CPD PF08302.11 EKX47290.1 - 2.6e-11 43.4 0.4 3.5e-09 36.5 0.5 2.3 1 1 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain TypeIII_RM_meth PF12564.8 EKX47290.1 - 0.13 12.4 0.2 0.6 10.3 0.0 2.1 2 0 0 2 2 2 0 Type III restriction/modification enzyme methylation subunit WD40 PF00400.32 EKX47291.1 - 1.8e-23 82.4 13.8 1.5e-07 32.0 0.5 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX47291.1 - 0.00079 19.7 0.6 0.12 12.7 0.1 3.0 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Snapin_Pallidin PF14712.6 EKX47293.1 - 0.00041 20.7 6.4 0.01 16.2 3.4 7.4 7 1 0 7 7 7 3 Snapin/Pallidin Fez1 PF06818.15 EKX47293.1 - 0.14 12.6 55.2 0.03 14.8 2.5 6.2 6 0 0 6 6 6 0 Fez1 GIT_CC PF16559.5 EKX47293.1 - 5.1 7.0 27.9 0.021 14.7 1.6 5.6 5 0 0 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor PCI PF01399.27 EKX47294.1 - 1.9e-12 47.6 1.4 4.4e-12 46.4 0.6 2.1 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 EKX47294.1 - 8.2e-08 31.8 1.2 6.1e-07 29.0 0.4 2.5 2 0 0 2 2 2 1 eIF3 subunit M, C-terminal helix Beta_helix PF13229.6 EKX47295.1 - 0.00011 22.1 0.3 0.00078 19.3 0.3 2.1 1 1 0 1 1 1 1 Right handed beta helix region DUF4957 PF16318.5 EKX47295.1 - 0.17 11.9 0.0 1.8 8.5 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4957) Peptidase_C2 PF00648.21 EKX47296.1 - 9.7e-10 37.9 0.0 1.4e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease RBR PF17208.3 EKX47296.1 - 0.047 14.4 3.3 0.047 14.4 3.3 1.9 2 0 0 2 2 2 0 RNA binding Region Kelch_5 PF13854.6 EKX47297.1 - 9.5e-16 57.4 0.1 3e-08 33.5 0.0 2.1 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.25 EKX47297.1 - 6.9e-13 48.0 0.5 6.1e-06 25.7 0.0 2.1 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.15 EKX47297.1 - 7.8e-12 44.7 0.5 6.6e-08 32.2 0.1 2.1 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 EKX47297.1 - 6.2e-11 42.2 0.2 0.00037 20.7 0.0 2.1 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 EKX47297.1 - 1.7e-10 40.7 0.1 5.4e-06 26.3 0.0 2.1 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.6 EKX47297.1 - 2.4e-07 30.9 5.4 0.007 16.6 0.0 3.1 3 0 0 3 3 3 2 Galactose oxidase, central domain WD40 PF00400.32 EKX47299.1 - 4.3e-59 195.1 34.6 2.6e-06 28.1 0.1 14.5 14 0 0 14 14 14 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX47299.1 - 1.5e-19 70.0 0.0 0.00017 21.8 0.0 9.2 4 2 4 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX47299.1 - 1.3e-09 37.5 6.2 0.0085 15.1 0.1 7.2 3 2 5 8 8 8 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EKX47299.1 - 4e-09 36.6 0.1 0.41 10.5 0.0 4.5 3 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 EKX47299.1 - 8.2e-06 24.6 1.1 0.052 12.1 0.0 4.7 4 2 1 5 5 5 1 Cytochrome D1 heme domain Nup160 PF11715.8 EKX47299.1 - 0.00033 19.4 3.0 1.2 7.6 0.1 4.3 3 2 1 4 4 4 2 Nucleoporin Nup120/160 SGL PF08450.12 EKX47299.1 - 0.0054 16.3 0.7 0.9 9.1 0.0 4.1 2 2 1 4 4 4 1 SMP-30/Gluconolactonase/LRE-like region Nucleoporin_N PF08801.11 EKX47299.1 - 0.0096 14.7 0.0 0.88 8.2 0.0 3.5 2 1 0 2 2 2 1 Nup133 N terminal like WD40_like PF17005.5 EKX47299.1 - 0.037 13.4 0.1 0.54 9.5 0.0 2.5 1 1 1 2 2 2 0 WD40-like domain DUF2415 PF10313.9 EKX47299.1 - 0.11 12.4 1.2 1.2 9.1 0.1 3.2 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) PD40 PF07676.12 EKX47299.1 - 0.17 11.9 8.8 1.1 9.3 0.0 5.4 7 0 0 7 7 6 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 EKX47299.1 - 2 9.0 8.8 4.5 7.9 0.0 5.6 8 0 0 8 8 7 0 PQQ-like domain EF-hand_1 PF00036.32 EKX47300.1 - 4.6e-35 116.6 4.9 7.4e-09 34.5 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EKX47300.1 - 2.9e-32 110.9 0.3 3.2e-16 59.5 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX47300.1 - 2.6e-26 89.3 4.2 1.9e-08 33.6 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EKX47300.1 - 5e-26 90.3 6.5 1.5e-12 47.1 0.4 3.6 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EKX47300.1 - 4.7e-21 73.3 5.7 1.2e-06 27.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EKX47300.1 - 5.5e-17 61.9 0.0 3.5e-11 43.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 EKX47300.1 - 1.3e-07 31.7 5.7 0.0062 16.7 0.4 2.9 1 1 2 3 3 3 3 Dockerin type I domain EF-hand_4 PF12763.7 EKX47300.1 - 2.3e-07 30.7 0.1 0.012 15.5 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 EKX47300.1 - 1.3e-06 29.2 0.0 3.2e-05 24.7 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 EKX47300.1 - 1.1e-05 25.7 0.0 0.0044 17.3 0.0 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF3349 PF11829.8 EKX47300.1 - 4e-05 24.3 0.2 0.58 11.0 0.0 2.9 1 1 2 3 3 3 2 Protein of unknown function (DUF3349) TerB PF05099.13 EKX47300.1 - 0.00047 20.1 0.1 0.77 9.7 0.0 2.5 1 1 2 3 3 3 2 Tellurite resistance protein TerB EFhand_Ca_insen PF08726.10 EKX47300.1 - 0.0027 17.8 0.2 0.01 15.9 0.0 2.1 2 1 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.13 EKX47300.1 - 0.0038 17.2 0.0 3.1 7.9 0.0 2.7 3 1 0 3 3 3 1 Uncharacterised protein family (UPF0154) MotA_activ PF09114.10 EKX47300.1 - 0.0045 17.1 1.1 0.16 12.1 0.1 2.4 2 1 0 2 2 2 1 Transcription factor MotA, activation domain VCBS PF13517.6 EKX47300.1 - 0.0048 17.4 1.8 0.043 14.4 1.4 2.4 2 1 0 2 2 2 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Poly_export PF02563.16 EKX47300.1 - 0.0065 16.7 0.3 6 7.2 0.0 3.0 1 1 2 3 3 3 1 Polysaccharide biosynthesis/export protein RNA_pol_Rpb4 PF03874.16 EKX47300.1 - 0.0072 16.7 0.7 1.6 9.1 0.2 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb4 YqeY PF09424.10 EKX47300.1 - 0.023 14.8 0.2 0.61 10.2 0.1 2.1 1 1 1 2 2 2 0 Yqey-like protein Caleosin PF05042.13 EKX47300.1 - 0.048 13.6 0.2 1.2 9.1 0.2 2.6 1 1 0 1 1 1 0 Caleosin related protein dCache_2 PF08269.11 EKX47300.1 - 0.078 12.1 0.0 0.56 9.3 0.0 1.9 1 1 1 2 2 2 0 Cache domain EF-hand_14 PF17959.1 EKX47300.1 - 0.086 13.2 0.1 4.6 7.6 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain SapB_1 PF05184.15 EKX47300.1 - 0.13 12.3 4.1 4.9 7.3 0.0 3.1 4 0 0 4 4 3 0 Saposin-like type B, region 1 C2 PF00168.30 EKX47301.1 - 3.8e-14 52.8 0.0 9.2e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain YbjQ_1 PF01906.17 EKX47301.1 - 0.025 15.2 6.4 3.6 8.3 0.5 3.4 3 0 0 3 3 3 0 Putative heavy-metal-binding zf-C2HC_2 PF13913.6 EKX47301.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type AAA_11 PF13086.6 EKX47305.1 - 0.56 9.9 0.0 0.56 9.9 0.0 2.8 2 1 0 2 2 2 0 AAA domain EF-hand_14 PF17959.1 EKX47305.1 - 4.1 7.8 12.0 43 4.5 1.0 4.7 3 1 0 4 4 4 0 EF-hand domain Gb3_synth PF04572.12 EKX47307.1 - 5.7e-16 58.9 0.3 2e-15 57.1 0.0 2.0 2 0 0 2 2 2 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.15 EKX47307.1 - 1.4e-08 35.2 0.0 3.1e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Pyr_redox_2 PF07992.14 EKX47308.1 - 3.4e-23 82.3 0.7 4.4e-16 59.0 0.1 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EKX47308.1 - 3.8e-17 62.6 0.3 4.9e-10 39.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EKX47308.1 - 1.7e-07 30.8 0.0 0.003 16.9 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EKX47308.1 - 4.7e-07 29.2 1.1 0.018 14.1 0.3 2.6 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.24 EKX47308.1 - 2.1e-06 27.6 2.1 0.046 13.3 0.0 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EKX47308.1 - 6e-06 26.4 0.7 0.027 14.7 0.1 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EKX47308.1 - 1.5e-05 24.3 0.0 0.012 14.8 0.1 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EKX47308.1 - 0.00019 21.4 1.2 0.094 12.7 0.0 3.1 2 1 1 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 EKX47308.1 - 0.00028 20.2 0.0 0.077 12.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.14 EKX47308.1 - 0.00052 19.0 0.8 0.18 10.6 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase TrkA_N PF02254.18 EKX47308.1 - 0.00071 19.8 0.1 0.51 10.6 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain Thi4 PF01946.17 EKX47308.1 - 0.00079 18.7 0.6 0.38 9.9 0.0 2.5 2 1 0 2 2 2 2 Thi4 family GIDA PF01134.22 EKX47308.1 - 0.00099 18.3 1.3 0.56 9.2 0.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_7 PF13241.6 EKX47308.1 - 0.0015 18.9 0.1 0.86 10.1 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 EKX47308.1 - 0.0026 16.9 1.3 1 8.4 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain AlaDh_PNT_C PF01262.21 EKX47308.1 - 0.0027 17.0 0.0 2.3 7.5 0.0 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EKX47308.1 - 0.0031 16.3 2.2 1.2 7.7 0.7 2.7 2 1 1 3 3 3 2 HI0933-like protein Sacchrp_dh_NADP PF03435.18 EKX47308.1 - 0.02 15.1 0.3 1.6 9.0 0.0 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EKX47308.1 - 0.047 13.8 0.1 10 6.2 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF1188 PF06690.11 EKX47308.1 - 0.054 13.0 0.0 2.6 7.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) ThiF PF00899.21 EKX47308.1 - 0.13 11.6 0.0 6.7 6.0 0.0 2.3 2 0 0 2 2 2 0 ThiF family 3HCDH_N PF02737.18 EKX47308.1 - 0.14 12.0 0.1 9.6 6.0 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 EKX47308.1 - 1.6 8.0 5.9 7 5.9 0.1 2.8 2 1 1 3 3 3 0 FAD dependent oxidoreductase RCC1 PF00415.18 EKX47309.1 - 2.7e-77 255.2 15.2 2.8e-14 53.5 0.0 7.1 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX47309.1 - 2.6e-44 148.2 33.0 6.5e-10 38.5 0.2 8.2 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Retro_M PF02813.14 EKX47309.1 - 0.44 11.0 1.8 12 6.4 0.0 3.7 4 1 1 5 5 5 0 Retroviral M domain Methyltransf_24 PF13578.6 EKX47310.1 - 7.4e-15 55.9 0.0 2e-14 54.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain TylF PF05711.11 EKX47310.1 - 1.5e-06 27.7 0.3 0.0029 16.9 0.0 2.1 2 0 0 2 2 2 2 Macrocin-O-methyltransferase (TylF) CmcI PF04989.12 EKX47310.1 - 2.6e-06 27.3 0.0 3.2e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_3 PF01596.17 EKX47310.1 - 0.02 14.1 0.1 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 O-methyltransferase Pro_CA PF00484.19 EKX47311.1 - 6e-42 143.6 0.2 1e-41 142.8 0.2 1.4 1 0 0 1 1 1 1 Carbonic anhydrase zf-C3HC4_4 PF15227.6 EKX47311.1 - 0.085 13.0 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RexA PF15969.5 EKX47312.1 - 0.2 11.2 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Intracellular sensor of Lambda phage, Abi component DUF5427 PF10310.9 EKX47314.1 - 0.075 12.0 12.6 0.086 11.8 12.6 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Hid1 PF12722.7 EKX47314.1 - 2 6.4 6.9 2 6.5 6.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DDHD PF02862.17 EKX47314.1 - 2.4 8.3 7.2 2.6 8.1 7.2 1.1 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 EKX47314.1 - 3.4 6.3 13.9 3.9 6.1 13.9 1.0 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 EKX47314.1 - 4.6 5.9 16.8 5 5.8 16.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SprA-related PF12118.8 EKX47314.1 - 4.7 6.2 16.9 5.8 6.0 16.9 1.1 1 0 0 1 1 1 0 SprA-related family Neur_chan_memb PF02932.16 EKX47314.1 - 8 6.4 6.0 8.1 6.4 6.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Mito_carr PF00153.27 EKX47315.1 - 1.4e-59 198.0 2.3 1.8e-23 82.2 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PCI PF01399.27 EKX47317.1 - 1.2e-14 54.7 0.5 2.4e-14 53.7 0.5 1.5 1 0 0 1 1 1 1 PCI domain Homeobox_KN PF05920.11 EKX47318.1 - 2.9e-12 46.3 0.7 8.1e-12 44.8 0.7 1.8 1 0 0 1 1 1 1 Homeobox KN domain PBC PF03792.13 EKX47318.1 - 3.9e-06 26.8 2.1 3.9e-06 26.8 2.1 1.8 2 0 0 2 2 2 1 PBC domain Homeodomain PF00046.29 EKX47318.1 - 3e-05 23.8 3.0 0.00023 21.0 0.3 3.0 3 0 0 3 3 3 1 Homeodomain UPF0184 PF03670.13 EKX47318.1 - 3.1 8.3 9.9 0.14 12.6 1.2 3.2 2 2 2 4 4 4 0 Uncharacterised protein family (UPF0184) RCC1 PF00415.18 EKX47319.1 - 4.4e-57 190.5 21.2 2.6e-15 56.8 0.5 5.1 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX47319.1 - 2.1e-30 103.8 27.1 1.3e-07 31.2 0.4 5.2 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat DUF3696 PF12476.8 EKX47319.1 - 1.5 9.3 3.0 20 5.7 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3696) zf-AN1 PF01428.16 EKX47320.1 - 1.2e-10 41.4 11.2 1.2e-10 41.4 11.2 2.1 2 0 0 2 2 2 1 AN1-like Zinc finger zf-A20 PF01754.16 EKX47320.1 - 9.7e-10 38.2 6.8 3e-09 36.7 6.8 1.9 1 0 0 1 1 1 1 A20-like zinc finger Dynein_light PF01221.18 EKX47320.1 - 0.026 14.8 1.1 0.052 13.9 0.7 1.6 1 1 1 2 2 2 0 Dynein light chain type 1 Tetraspanin PF00335.20 EKX47321.1 - 2.1e-05 24.4 14.6 5.7e-05 22.9 14.6 1.7 1 1 0 1 1 1 1 Tetraspanin family FtsX PF02687.21 EKX47321.1 - 0.00088 19.7 8.3 0.0069 16.8 2.0 2.2 2 0 0 2 2 2 2 FtsX-like permease family PDR_assoc PF08370.11 EKX47321.1 - 0.0011 18.7 0.2 0.0035 17.0 0.2 1.9 1 0 0 1 1 1 1 Plant PDR ABC transporter associated DUF2142 PF09913.9 EKX47321.1 - 0.19 10.6 6.2 0.086 11.7 3.5 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2142) HisKA_7TM PF16927.5 EKX47321.1 - 0.2 11.7 6.5 0.28 11.2 5.2 1.8 1 1 1 2 2 2 0 N-terminal 7TM region of histidine kinase DUF2207 PF09972.9 EKX47321.1 - 0.33 9.7 1.9 0.5 9.1 1.9 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) RR_TM4-6 PF06459.12 EKX47322.1 - 0.83 9.4 5.3 1.1 9.1 4.3 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 EF-hand_1 PF00036.32 EKX47323.1 - 1.4e-23 80.6 9.5 3e-06 26.4 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EKX47323.1 - 5.2e-21 74.9 9.8 8.6e-12 45.3 2.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX47323.1 - 8.1e-20 69.0 7.4 2.2e-05 24.0 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EKX47323.1 - 1e-17 62.7 5.1 4.2e-07 29.2 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EKX47323.1 - 7.3e-15 54.6 9.2 2.4e-05 24.1 0.3 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_11 PF08976.11 EKX47323.1 - 3.1e-06 28.0 0.3 0.021 15.7 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EKX47323.1 - 0.00047 20.5 0.8 0.68 10.3 0.2 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EKX47323.1 - 0.0018 18.2 3.8 11 6.0 0.0 3.9 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand DUF2207 PF09972.9 EKX47323.1 - 0.013 14.3 0.5 0.015 14.1 0.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Dockerin_1 PF00404.18 EKX47323.1 - 0.018 15.3 0.1 1.3 9.3 0.1 2.3 2 0 0 2 2 2 0 Dockerin type I domain Caleosin PF05042.13 EKX47323.1 - 0.055 13.4 0.6 6.2 6.7 0.0 2.9 2 1 1 3 3 3 0 Caleosin related protein TRAP-delta PF05404.12 EKX47324.1 - 2.9e-06 26.9 8.8 3.6e-06 26.6 4.4 2.9 1 1 1 2 2 2 1 Translocon-associated protein, delta subunit precursor (TRAP-delta) Filamin PF00630.19 EKX47324.1 - 0.01 16.6 0.1 0.014 16.2 0.1 1.3 1 0 0 1 1 1 0 Filamin/ABP280 repeat DUF4251 PF14059.6 EKX47324.1 - 0.018 15.0 0.2 0.027 14.4 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4251) GBS_Bsp-like PF08481.10 EKX47324.1 - 0.065 13.4 0.0 0.16 12.1 0.0 1.8 1 1 0 1 1 1 0 GBS Bsp-like repeat MG2 PF01835.19 EKX47324.1 - 0.076 13.5 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 MG2 domain EF-hand_7 PF13499.6 EKX47326.1 - 9.6e-18 64.4 24.4 9.3e-10 38.8 5.6 3.4 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 EKX47326.1 - 3.7e-17 60.5 13.0 0.00035 19.9 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EKX47326.1 - 7.3e-14 50.4 8.3 0.0023 17.7 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EKX47326.1 - 5.7e-10 38.2 10.1 0.00024 20.4 0.0 4.5 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 EKX47326.1 - 2.5e-05 24.0 13.3 0.19 11.6 0.2 4.2 4 0 0 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX47326.1 - 0.00011 22.5 13.9 0.12 12.7 0.9 3.9 2 1 2 4 4 4 3 Secreted protein acidic and rich in cysteine Ca binding region ASCH PF04266.14 EKX47326.1 - 4.2 8.0 7.5 4.4 7.9 0.8 2.8 2 1 0 3 3 3 0 ASCH domain UDPGP PF01704.18 EKX47327.1 - 5.6e-122 407.3 0.0 6.3e-122 407.2 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase MCM PF00493.23 EKX47330.1 - 1.9e-76 256.1 0.2 4e-55 186.3 0.1 2.4 1 1 1 2 2 2 2 MCM P-loop domain MCM_OB PF17207.3 EKX47330.1 - 6.9e-33 113.2 0.7 1.3e-32 112.3 0.7 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EKX47330.1 - 1.2e-22 80.1 0.6 2.4e-22 79.2 0.6 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EKX47330.1 - 1.6e-18 67.2 0.6 3.6e-18 66.0 0.6 1.6 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 EKX47330.1 - 1.1e-06 28.7 0.3 1e-05 25.6 0.0 2.6 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) PIG-S PF10510.9 EKX47330.1 - 0.014 14.3 0.1 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Phosphatidylinositol-glycan biosynthesis class S protein AAA_16 PF13191.6 EKX47330.1 - 0.047 14.1 2.0 0.39 11.1 0.1 2.9 3 1 0 3 3 3 0 AAA ATPase domain Mg_chelatase_C PF13335.6 EKX47330.1 - 0.054 14.1 0.1 0.25 12.0 0.1 2.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal MCM_bind PF09739.9 EKX47330.1 - 0.12 10.9 0.0 0.12 10.9 0.0 1.5 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor PsbW PF07123.12 EKX47331.1 - 0.013 15.5 1.0 0.03 14.3 1.0 1.7 1 1 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) DUF4148 PF13663.6 EKX47331.1 - 3.8 7.8 7.9 8.4 6.7 3.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) YjbE PF11106.8 EKX47331.1 - 9.3 6.5 11.3 2.5 8.4 2.1 2.1 1 1 1 2 2 2 0 Exopolysaccharide production protein YjbE Polyketide_cyc PF03364.20 EKX47332.1 - 1.5e-08 34.9 0.0 2.1e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 EKX47332.1 - 2e-05 24.9 0.0 2.8e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport COXG PF06240.13 EKX47332.1 - 0.047 13.4 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) SET PF00856.28 EKX47333.1 - 0.00034 21.0 0.0 0.0014 19.0 0.0 1.9 1 1 0 1 1 1 1 SET domain RNase_P_p30 PF01876.16 EKX47333.1 - 0.17 11.4 0.0 4.9 6.6 0.0 2.2 2 0 0 2 2 2 0 RNase P subunit p30 PDZ PF00595.24 EKX47335.1 - 2.3e-09 37.4 0.0 5.9e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain UBX PF00789.20 EKX47335.1 - 2.6e-09 37.1 0.0 6.7e-09 35.8 0.0 1.7 1 1 0 1 1 1 1 UBX domain Thioredoxin PF00085.20 EKX47335.1 - 6.9e-09 35.6 0.0 1.5e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin PDZ_6 PF17820.1 EKX47335.1 - 8.5e-08 31.9 0.1 2.1e-07 30.7 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX47335.1 - 3.3e-07 30.5 0.0 9.5e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 PDZ domain UBA PF00627.31 EKX47335.1 - 1.9e-06 27.6 0.0 3.7e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain UBA_3 PF09288.10 EKX47335.1 - 0.031 14.1 0.0 0.12 12.2 0.0 2.0 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Thioredoxin_4 PF13462.6 EKX47335.1 - 0.031 14.4 0.6 0.09 12.9 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin Desmo_N PF06771.11 EKX47335.1 - 0.13 12.7 0.1 3.8 7.9 0.0 2.6 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus DUF5344 PF17279.2 EKX47336.1 - 0.033 14.8 1.6 0.093 13.3 1.6 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5344) MutS_II PF05188.17 EKX47336.1 - 0.39 11.0 3.4 9.4 6.5 1.1 2.4 2 0 0 2 2 2 0 MutS domain II Exonuc_VII_L PF02601.15 EKX47336.1 - 4 6.9 9.1 0.52 9.8 4.1 1.8 1 1 1 2 2 2 0 Exonuclease VII, large subunit AMP-binding PF00501.28 EKX47337.1 - 4.5e-96 322.0 0.0 5.4e-96 321.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EKX47337.1 - 1.9e-22 80.0 0.1 3.4e-22 79.2 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EKX47337.1 - 1.4e-16 60.1 2.8 1.4e-16 60.1 2.8 2.2 3 0 0 3 3 3 1 Acetyl-coenzyme A synthetase N-terminus Yippee-Mis18 PF03226.14 EKX47338.1 - 4.1e-11 43.0 1.0 6.9e-11 42.3 1.0 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Cadherin_4 PF17803.1 EKX47339.1 - 0.011 16.3 5.2 4.6 8.0 0.1 4.6 4 0 0 4 4 4 0 Bacterial cadherin-like domain La PF05383.17 EKX47340.1 - 3.4e-24 84.7 0.0 9.5e-24 83.2 0.0 1.8 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 EKX47340.1 - 7.5e-06 25.7 0.1 2e-05 24.3 0.1 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aldo_ket_red PF00248.21 EKX47341.1 - 4.8e-58 196.7 0.0 5.6e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CLN3 PF02487.17 EKX47342.1 - 2e-29 102.9 6.0 2.3e-29 102.7 6.0 1.0 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 EKX47342.1 - 0.0016 17.4 6.6 0.0016 17.4 6.6 1.8 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF2625 PF10946.8 EKX47342.1 - 0.031 13.3 0.0 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF2625 Macoilin PF09726.9 EKX47342.1 - 6.1 5.3 6.6 7.2 5.0 6.6 1.1 1 0 0 1 1 1 0 Macoilin family EF-hand_1 PF00036.32 EKX47343.1 - 7e-15 53.4 0.9 1.7e-05 24.0 0.0 5.4 6 0 0 6 6 6 2 EF hand EF-hand_6 PF13405.6 EKX47343.1 - 6.2e-14 50.7 0.2 0.00014 21.5 0.0 5.8 5 0 0 5 5 5 2 EF-hand domain EF-hand_7 PF13499.6 EKX47343.1 - 6.6e-12 45.7 5.0 0.00029 21.2 0.0 4.9 4 2 1 5 5 5 2 EF-hand domain pair EF-hand_8 PF13833.6 EKX47343.1 - 8.6e-12 44.7 1.7 0.0086 15.9 0.1 6.1 4 2 2 6 6 6 3 EF-hand domain pair EF-hand_5 PF13202.6 EKX47343.1 - 1.2e-08 34.0 0.9 0.0036 16.7 0.0 3.8 3 0 0 3 3 3 2 EF hand EF-hand_14 PF17959.1 EKX47343.1 - 0.0015 18.8 2.1 1.3 9.5 0.0 4.5 3 2 1 4 4 4 1 EF-hand domain Clp_N PF02861.20 EKX47343.1 - 0.048 13.8 0.9 3.4 7.9 0.1 3.5 3 0 0 3 3 3 0 Clp amino terminal domain, pathogenicity island component EF-hand_9 PF14658.6 EKX47343.1 - 0.13 12.6 0.0 6.6 7.1 0.0 2.9 2 1 0 2 2 2 0 EF-hand domain zf-rbx1 PF12678.7 EKX47346.1 - 5.1e-25 87.5 14.4 6.8e-25 87.1 14.4 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EKX47346.1 - 1.6e-17 63.3 10.7 2e-17 63.0 10.7 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EKX47346.1 - 1.7e-06 28.3 16.5 8.9e-05 22.7 16.5 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX47346.1 - 2.7e-05 23.9 4.0 2.7e-05 23.9 4.0 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX47346.1 - 0.00095 19.0 12.9 0.0093 15.8 12.9 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EKX47346.1 - 0.0015 18.2 2.4 0.0015 18.2 2.4 2.5 2 1 0 2 2 2 1 RING-like zinc finger FANCL_C PF11793.8 EKX47346.1 - 0.15 12.3 10.0 0.77 10.0 10.1 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 EKX47346.1 - 0.15 11.9 12.4 21 5.1 0.3 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX47346.1 - 0.42 10.7 7.9 1.4 9.0 7.9 1.9 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 EKX47346.1 - 0.88 9.2 16.3 0.098 12.3 5.1 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EKX47346.1 - 3.6 7.6 13.2 15 5.7 13.2 2.1 1 1 0 1 1 1 0 zinc-RING finger domain Hydrolase_4 PF12146.8 EKX47348.1 - 1.7e-13 50.4 0.1 2.7e-11 43.2 0.1 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EKX47348.1 - 1.4e-10 41.3 0.1 2.5e-10 40.5 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EKX47348.1 - 2.2e-07 30.7 0.1 7.4e-06 25.7 0.1 2.2 1 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 EKX47348.1 - 4.1e-05 23.2 0.2 0.00018 21.1 0.2 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.13 EKX47348.1 - 0.0011 18.7 0.1 0.0052 16.5 0.1 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EKX47348.1 - 0.003 18.2 0.0 0.005 17.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.13 EKX47348.1 - 0.004 15.7 0.0 0.79 8.2 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II BAAT_C PF08840.11 EKX47348.1 - 0.0068 16.3 0.0 0.041 13.8 0.0 2.0 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 EKX47348.1 - 0.011 15.3 0.0 0.54 9.8 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 EKX47348.1 - 0.044 13.6 0.0 0.068 13.0 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PhoPQ_related PF10142.9 EKX47348.1 - 0.2 10.3 0.1 1.5 7.4 0.0 1.9 2 0 0 2 2 2 0 PhoPQ-activated pathogenicity-related protein Lactamase_B_2 PF12706.7 EKX47349.1 - 2.8e-33 115.1 0.0 3.6e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EKX47349.1 - 8.1e-15 55.1 0.0 1.3e-14 54.5 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EKX47349.1 - 0.0032 17.5 0.0 0.063 13.3 0.0 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily ABC_membrane PF00664.23 EKX47350.1 - 5.2e-89 298.5 13.8 3.2e-51 174.6 7.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EKX47350.1 - 1.7e-69 232.6 1.3 1.4e-33 116.3 0.0 3.0 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 EKX47350.1 - 3e-13 49.7 0.7 0.0036 16.8 0.1 4.4 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EKX47350.1 - 2.2e-09 37.7 0.9 0.04 14.2 0.0 4.9 4 1 0 4 4 4 2 AAA domain AAA_29 PF13555.6 EKX47350.1 - 6.2e-09 35.5 1.0 0.0026 17.5 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 EKX47350.1 - 8.1e-08 32.4 0.0 0.01 15.6 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EKX47350.1 - 2.3e-07 30.9 0.0 0.03 14.2 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EKX47350.1 - 3.1e-07 30.9 1.3 0.023 15.1 0.5 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 EKX47350.1 - 2.5e-06 27.3 0.1 0.13 11.9 0.0 3.1 3 1 0 3 3 3 2 AAA domain AAA PF00004.29 EKX47350.1 - 6.1e-06 26.7 0.1 0.69 10.3 0.1 4.3 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 EKX47350.1 - 9.7e-06 25.6 0.0 0.12 12.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 EKX47350.1 - 9.2e-05 22.0 0.0 0.15 11.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region KAP_NTPase PF07693.14 EKX47350.1 - 9.3e-05 21.8 0.1 0.0082 15.4 0.0 2.6 2 1 0 2 2 2 1 KAP family P-loop domain AAA_18 PF13238.6 EKX47350.1 - 0.00011 22.7 0.0 0.25 11.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EKX47350.1 - 0.00016 21.7 0.3 1.4 9.0 0.0 3.4 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 EKX47350.1 - 0.00021 20.6 0.1 0.094 12.0 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin AAA_23 PF13476.6 EKX47350.1 - 0.00023 21.7 1.3 0.83 10.1 0.1 3.0 3 0 0 3 3 3 2 AAA domain APS_kinase PF01583.20 EKX47350.1 - 0.00037 20.4 0.1 0.46 10.4 0.0 2.7 2 0 0 2 2 2 1 Adenylylsulphate kinase G-alpha PF00503.20 EKX47350.1 - 0.00068 18.9 0.1 0.22 10.6 0.0 2.5 2 0 0 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 EKX47350.1 - 0.00093 19.3 0.0 2.1 8.5 0.0 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase SbcCD_C PF13558.6 EKX47350.1 - 0.0021 18.3 4.2 1.9 8.7 0.6 3.8 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 EKX47350.1 - 0.003 17.7 0.0 1.7 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EKX47350.1 - 0.003 17.3 0.0 3.3 7.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EKX47350.1 - 0.0031 17.1 0.1 2.6 7.6 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.6 EKX47350.1 - 0.0056 17.1 3.5 4.3 7.8 0.0 3.9 3 1 0 3 3 3 1 AAA domain DUF815 PF05673.13 EKX47350.1 - 0.0066 15.6 0.0 2.8 7.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.12 EKX47350.1 - 0.014 15.3 0.5 3.4 7.6 0.0 3.0 3 0 0 3 3 2 0 NACHT domain ATP_bind_1 PF03029.17 EKX47350.1 - 0.014 15.2 0.1 5.2 6.8 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 EKX47350.1 - 0.018 14.2 0.1 3.9 6.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DEAD PF00270.29 EKX47350.1 - 0.02 14.7 0.7 9.8 5.9 0.1 3.7 3 1 0 3 3 3 0 DEAD/DEAH box helicase ABC_ATPase PF09818.9 EKX47350.1 - 0.023 13.5 1.1 2.8 6.6 0.0 2.9 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Rad17 PF03215.15 EKX47350.1 - 0.037 14.0 0.0 9.6 6.1 0.0 2.7 2 0 0 2 2 2 0 Rad17 P-loop domain NTPase_1 PF03266.15 EKX47350.1 - 0.05 13.5 0.2 13 5.6 0.0 2.9 3 0 0 3 3 3 0 NTPase ATP-synt_ab PF00006.25 EKX47350.1 - 0.055 13.1 0.0 4.1 7.0 0.0 2.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PRK PF00485.18 EKX47350.1 - 0.072 12.8 0.1 7 6.3 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 EKX47350.1 - 0.075 13.4 0.0 18 5.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 EKX47350.1 - 0.087 12.5 0.0 12 5.6 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Roc PF08477.13 EKX47350.1 - 0.09 13.0 0.1 17 5.7 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF3487 PF11990.8 EKX47350.1 - 0.14 12.0 5.4 0.26 11.2 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) DUF87 PF01935.17 EKX47350.1 - 0.35 10.9 5.3 4 7.5 0.0 3.0 3 1 0 3 3 2 0 Helicase HerA, central domain ATPase PF06745.13 EKX47350.1 - 0.76 9.1 3.9 26 4.1 0.2 3.1 3 0 0 3 3 3 0 KaiC Bac_rhodopsin PF01036.18 EKX47352.1 - 5.5e-37 127.5 20.5 6.7e-37 127.2 20.5 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Nucleos_tra2_C PF07662.13 EKX47352.1 - 0.19 11.5 11.0 0.074 12.9 4.4 2.2 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter C-terminus DUF4131 PF13567.6 EKX47352.1 - 2.3 7.9 11.4 2.3 7.9 3.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4191 PF13829.6 EKX47352.1 - 3.8 6.8 10.8 0.29 10.4 3.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Bac_rhodopsin PF01036.18 EKX47353.1 - 5e-37 127.6 20.5 6e-37 127.4 20.5 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Nucleos_tra2_C PF07662.13 EKX47353.1 - 0.18 11.6 11.0 0.07 13.0 4.4 2.2 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter C-terminus DUF4131 PF13567.6 EKX47353.1 - 3.1 7.4 12.0 3.1 7.4 3.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4191 PF13829.6 EKX47353.1 - 4.2 6.6 11.1 0.16 11.3 2.6 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4191) SpoU_methylase PF00588.19 EKX47354.1 - 3.8e-25 88.7 0.0 6.9e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family zf-C3HC4_3 PF13920.6 EKX47355.1 - 1.2e-13 50.7 11.7 1.2e-13 50.7 11.7 2.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX47355.1 - 5.5e-06 26.1 11.0 5.5e-06 26.1 11.0 2.4 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EKX47355.1 - 0.00016 21.9 11.7 0.00016 21.9 11.7 2.8 3 1 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 EKX47355.1 - 0.0057 16.6 11.4 0.0057 16.6 11.4 2.6 2 1 0 2 2 2 1 zinc-RING finger domain CD34_antigen PF06365.12 EKX47355.1 - 0.0062 16.2 0.1 0.0098 15.5 0.1 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family zf-C3HC4_2 PF13923.6 EKX47355.1 - 0.021 14.6 13.2 0.021 14.6 13.2 3.0 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DUF4446 PF14584.6 EKX47355.1 - 0.089 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF5336 PF17270.2 EKX47355.1 - 0.19 11.3 0.1 18 4.9 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5336) VirB8 PF04335.13 EKX47355.1 - 0.64 9.8 3.1 3.9 7.2 0.1 2.1 1 1 1 2 2 2 0 VirB8 protein Sushi PF00084.20 EKX47356.1 - 3.1e-19 69.3 20.9 0.00039 21.0 0.3 6.5 6 1 0 6 6 6 5 Sushi repeat (SCR repeat) CCDC53 PF10152.9 EKX47356.1 - 0.01 16.2 8.3 0.014 15.8 2.9 2.4 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex T2SSM PF04612.12 EKX47356.1 - 5.8 7.0 9.3 10 6.1 9.3 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M DUF4464 PF14713.6 EKX47357.1 - 1.8e-97 325.3 3.1 2.1e-97 325.1 3.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) Ig_4 PF16680.5 EKX47359.1 - 0.083 13.2 0.0 0.24 11.7 0.0 1.8 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain RWP-RK PF02042.15 EKX47360.1 - 3.1e-10 39.9 0.1 4.9e-10 39.2 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain mCpol PF18182.1 EKX47360.1 - 0.075 13.4 0.1 0.1 12.9 0.1 1.2 1 0 0 1 1 1 0 minimal CRISPR polymerase domain HTH_8 PF02954.19 EKX47360.1 - 0.14 12.0 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Beta-lactamase PF00144.24 EKX47361.1 - 1.1e-19 70.9 0.0 2.6e-19 69.7 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 EKX47361.1 - 0.07 12.6 0.0 2.5 7.5 0.0 2.2 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 EKX47361.1 - 0.12 12.0 0.0 9 5.8 0.0 2.3 2 0 0 2 2 2 0 Beta-lactamase enzyme family DTC PF18102.1 EKX47362.1 - 2.4e-54 183.1 0.1 3.1e-54 182.7 0.1 1.2 1 0 0 1 1 1 1 Deltex C-terminal domain zf-RING_2 PF13639.6 EKX47362.1 - 1.7e-06 28.2 8.9 3.3e-06 27.3 8.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EKX47362.1 - 0.00045 20.2 7.7 0.029 14.4 4.4 2.4 2 0 0 2 2 2 2 RING-type zinc-finger WWE PF02825.20 EKX47362.1 - 0.0013 19.2 0.0 0.0025 18.4 0.0 1.4 1 0 0 1 1 1 1 WWE domain Zn-C2H2_12 PF18112.1 EKX47362.1 - 0.015 15.7 1.2 1.1 9.8 0.2 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-ANAPC11 PF12861.7 EKX47362.1 - 0.017 15.2 4.0 0.037 14.1 4.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 EKX47362.1 - 0.019 14.8 9.9 0.32 10.9 2.8 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX47362.1 - 0.032 14.1 4.2 0.092 12.6 4.4 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EKX47362.1 - 0.06 13.1 12.2 0.046 13.5 9.0 2.3 2 1 0 2 2 2 0 RING-like zinc finger zinc_ribbon_9 PF14369.6 EKX47362.1 - 0.087 13.1 1.6 0.95 9.8 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon zf-RING_5 PF14634.6 EKX47362.1 - 0.3 11.1 9.7 0.51 10.4 9.2 1.7 1 1 1 2 2 2 0 zinc-RING finger domain zf-rbx1 PF12678.7 EKX47362.1 - 2.1 8.7 12.1 6.1 7.2 12.1 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain Methyltransf_16 PF10294.9 EKX47363.1 - 3.8e-23 82.1 0.5 6e-23 81.4 0.1 1.4 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EKX47363.1 - 0.00012 21.9 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EKX47363.1 - 0.00058 19.3 0.0 0.00083 18.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 EKX47363.1 - 0.0031 18.2 0.2 0.0076 17.0 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EKX47363.1 - 0.0079 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EKX47363.1 - 0.018 15.7 0.0 0.037 14.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EKX47363.1 - 0.028 15.1 0.0 0.059 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 EKX47363.1 - 0.09 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Thymidylat_synt PF00303.19 EKX47364.1 - 8e-117 389.1 0.0 9.9e-117 388.8 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.19 EKX47364.1 - 8.1e-36 123.2 0.0 1.2e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Dihydrofolate reductase Asp PF00026.23 EKX47365.1 - 8.7e-21 74.6 0.0 3e-11 43.3 0.0 3.2 3 0 0 3 3 3 3 Eukaryotic aspartyl protease TAXi_N PF14543.6 EKX47365.1 - 0.00026 21.3 0.0 0.0032 17.7 0.0 2.5 2 1 1 3 3 3 1 Xylanase inhibitor N-terminal RTT107_BRCT_5 PF16770.5 EKX47365.1 - 0.015 15.2 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain DASH_Duo1 PF08651.10 EKX47368.1 - 0.26 11.1 4.8 10 6.0 0.1 3.2 1 1 2 3 3 3 0 DASH complex subunit Duo1 Nucleoside_tran PF01733.18 EKX47368.1 - 0.42 10.0 0.0 0.42 10.0 0.0 1.9 3 0 0 3 3 3 0 Nucleoside transporter DUF4635 PF15466.6 EKX47371.1 - 0.027 14.0 0.3 0.29 10.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) PDEase_I_N PF08499.12 EKX47371.1 - 0.034 14.0 0.0 0.083 12.7 0.0 1.6 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal Ank_2 PF12796.7 EKX47372.1 - 2.8e-31 107.9 16.1 7.7e-08 32.8 0.0 3.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.30 EKX47372.1 - 2.4e-23 81.5 4.8 3.2e-06 27.3 0.1 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 EKX47372.1 - 2.3e-20 70.5 6.0 5.5e-05 23.3 0.0 6.0 6 1 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 EKX47372.1 - 3.6e-20 72.0 6.5 1.9e-06 28.3 0.2 5.2 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX47372.1 - 3.4e-17 62.3 9.9 4.9e-05 23.5 0.2 4.9 4 1 1 5 5 5 3 Ankyrin repeats (many copies) ATP-gua_Ptrans PF00217.19 EKX47373.1 - 1.9e-31 109.2 0.0 2.7e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 EKX47373.1 - 4.4e-11 43.0 0.0 1.7e-10 41.2 0.0 2.0 2 0 0 2 2 2 1 ATP:guanido phosphotransferase, N-terminal domain TspO_MBR PF03073.15 EKX47374.1 - 8.6e-18 64.7 10.2 8.6e-18 64.7 10.2 1.5 1 1 0 1 1 1 1 TspO/MBR family UQ_con PF00179.26 EKX47375.1 - 1.1e-22 80.2 0.0 1.5e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EKX47375.1 - 0.018 14.7 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 EKX47375.1 - 0.16 11.9 0.1 0.52 10.2 0.0 1.9 2 1 0 2 2 2 0 UEV domain HTH_Tnp_Tc5 PF03221.16 EKX47376.1 - 1.8e-06 27.9 0.4 6.6e-06 26.1 0.4 1.9 1 1 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_10 PF04967.12 EKX47376.1 - 0.018 14.8 0.1 3.1 7.7 0.0 2.5 2 0 0 2 2 2 0 HTH DNA binding domain HTH_3 PF01381.22 EKX47376.1 - 0.066 13.3 0.1 1.3 9.2 0.0 2.6 2 1 0 2 2 2 0 Helix-turn-helix CENP-B_N PF04218.13 EKX47376.1 - 0.2 11.3 1.3 1.5 8.5 0.1 3.1 3 1 0 3 3 3 0 CENP-B N-terminal DNA-binding domain Exo_endo_phos PF03372.23 EKX47377.1 - 5.9e-12 45.6 0.0 8.7e-11 41.8 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DSPc PF00782.20 EKX47378.1 - 2.7e-27 95.2 0.1 3.1e-27 95.0 0.1 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF4116 PF13475.6 EKX47378.1 - 0.079 12.7 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Nup160 PF11715.8 EKX47379.1 - 0.00025 19.9 0.8 0.002 16.9 0.8 2.1 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EKX47379.1 - 0.0039 16.0 0.1 0.0064 15.3 0.1 1.3 1 0 0 1 1 1 1 Nup133 N terminal like KH_1 PF00013.29 EKX47380.1 - 5.1e-08 32.6 0.2 6.6e-07 29.1 0.2 2.4 2 0 0 2 2 2 1 KH domain KH_4 PF13083.6 EKX47380.1 - 2.9e-06 27.1 1.6 3e-06 27.0 0.2 1.7 2 0 0 2 2 2 1 KH domain KH_2 PF07650.17 EKX47380.1 - 0.043 13.6 1.3 0.051 13.4 0.2 1.7 2 0 0 2 2 2 0 KH domain TMPIT PF07851.13 EKX47381.1 - 0.0045 16.3 4.5 0.0045 16.3 4.5 2.2 2 0 0 2 2 2 1 TMPIT-like protein Cnn_1N PF07989.11 EKX47381.1 - 0.0051 16.9 2.4 0.0051 16.9 2.4 4.4 5 0 0 5 5 5 1 Centrosomin N-terminal motif 1 DUF724 PF05266.14 EKX47381.1 - 0.021 14.6 4.4 0.021 14.6 4.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF724) DASH_Dam1 PF08653.10 EKX47381.1 - 0.04 13.7 3.6 3.2 7.6 0.3 3.6 3 1 0 3 3 3 0 DASH complex subunit Dam1 DDE_Tnp_1 PF01609.21 EKX47381.1 - 0.052 13.2 0.2 0.1 12.2 0.2 1.5 1 0 0 1 1 1 0 Transposase DDE domain E1_UFD PF09358.10 EKX47381.1 - 0.93 10.2 4.3 1.3 9.8 2.2 2.4 2 1 0 2 2 2 0 Ubiquitin fold domain DNA_methylase PF00145.17 EKX47381.1 - 1.3 8.3 8.5 0.87 8.9 0.3 2.2 2 0 0 2 2 2 0 C-5 cytosine-specific DNA methylase Fib_alpha PF08702.10 EKX47381.1 - 5.1 7.3 24.0 3.4 7.9 4.1 2.9 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family USP8_interact PF08941.10 EKX47381.1 - 5.7 6.7 10.8 0.74 9.6 3.7 2.5 2 0 0 2 2 2 0 USP8 interacting Sugar_tr PF00083.24 EKX47382.1 - 5.6e-24 84.8 25.1 1e-15 57.6 8.4 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EKX47382.1 - 8.5e-23 80.8 30.2 1e-22 80.6 30.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EKX47382.1 - 0.0015 17.1 1.9 0.002 16.6 0.9 1.7 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) 60KD_IMP PF02096.20 EKX47382.1 - 0.032 14.1 0.6 0.052 13.4 0.6 1.5 1 0 0 1 1 1 0 60Kd inner membrane protein MASE5 PF17178.4 EKX47382.1 - 0.057 13.2 6.7 0.041 13.7 4.5 1.8 2 0 0 2 2 2 0 Membrane-associated sensor NLRC4_HD PF17889.1 EKX47382.1 - 0.21 12.0 0.1 0.35 11.2 0.1 1.4 1 0 0 1 1 1 0 NLRC4 helical domain DUF4728 PF15860.5 EKX47382.1 - 2.8 8.7 9.1 0.07 13.8 1.6 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4728) MerC PF03203.14 EKX47382.1 - 3.4 8.1 14.2 0.037 14.5 1.3 3.2 2 1 0 2 2 2 0 MerC mercury resistance protein RCC1 PF00415.18 EKX47383.1 - 3e-33 114.2 7.1 5.1e-15 55.8 0.0 3.1 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX47383.1 - 1.3e-17 63.1 21.0 2.5e-09 36.7 5.1 3.4 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat GDP_Man_Dehyd PF16363.5 EKX47385.1 - 6.6e-71 239.4 0.0 1.6e-70 238.2 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EKX47385.1 - 8.7e-59 198.9 0.0 1.1e-58 198.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EKX47385.1 - 9.7e-26 90.4 0.0 1.4e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EKX47385.1 - 5.9e-20 71.6 0.0 2.5e-19 69.5 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EKX47385.1 - 1.9e-18 66.6 0.1 1.5e-17 63.6 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 EKX47385.1 - 1.9e-15 56.7 0.0 4.1e-15 55.6 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 EKX47385.1 - 0.00084 18.8 0.0 0.0063 16.0 0.0 2.2 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EKX47385.1 - 0.046 13.6 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 KR domain NmrA PF05368.13 EKX47385.1 - 0.11 12.0 0.0 0.89 9.1 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family PARP PF00644.20 EKX47386.1 - 2.4e-29 102.3 0.0 2.4e-29 102.3 0.0 2.8 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 EKX47386.1 - 3.9e-17 62.6 3.6 9.5e-17 61.4 3.6 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain PTCB-BRCT PF12738.7 EKX47386.1 - 1.4e-06 28.1 0.6 4e-06 26.7 0.1 2.0 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 EKX47386.1 - 1.3e-05 25.5 0.1 7.7e-05 23.0 0.1 2.3 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain WGR PF05406.15 EKX47386.1 - 3.7e-05 23.7 0.3 3.7e-05 23.7 0.3 3.0 3 0 0 3 3 3 1 WGR domain BRCT_2 PF16589.5 EKX47386.1 - 0.0011 19.3 0.0 0.0049 17.2 0.0 2.1 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DUF4192 PF13830.6 EKX47386.1 - 9 6.3 8.7 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) zf-MIZ PF02891.20 EKX47387.1 - 2.3e-13 49.7 6.2 3.3e-13 49.2 6.2 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EKX47387.1 - 5.7e-08 32.5 3.4 9.2e-08 31.8 3.4 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PKD_channel PF08016.12 EKX47388.1 - 7.8e-23 80.8 34.6 6.2e-18 64.7 18.6 2.9 3 0 0 3 3 3 2 Polycystin cation channel C2 PF00168.30 EKX47388.1 - 1.6e-16 60.4 0.0 4.9e-16 58.9 0.0 1.8 1 0 0 1 1 1 1 C2 domain Ion_trans PF00520.31 EKX47388.1 - 2.9e-07 30.0 36.5 7e-06 25.4 36.5 2.3 1 1 0 1 1 1 1 Ion transport protein BHD_3 PF10405.9 EKX47391.1 - 3.7e-13 49.7 0.0 8.1e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 EKX47391.1 - 5.8e-10 38.9 0.1 1.3e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 EKX47391.1 - 2.7e-05 25.0 0.0 9e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Rad4 PF03835.15 EKX47391.1 - 2.7e-05 23.9 0.0 6.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 EKX47391.1 - 0.009 16.5 0.0 0.021 15.2 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily YojJ PF10372.9 EKX47391.1 - 0.018 15.1 0.9 0.16 12.0 0.0 2.6 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus OS-D PF03392.13 EKX47391.1 - 0.45 10.6 3.3 0.45 10.6 1.2 2.1 2 0 0 2 2 2 0 Insect pheromone-binding family, A10/OS-D Phycoerythr_ab PF02972.14 EKX47392.1 - 7.2e-07 28.9 0.0 1.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Phycoerythrin, alpha/beta chain TAT_signal PF10518.9 EKX47392.1 - 0.0015 18.3 4.2 0.0015 18.3 4.2 2.5 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence DUF2890 PF11081.8 EKX47392.1 - 1.3 9.1 3.8 1.1 9.4 2.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) PsbQ PF05757.11 EKX47392.1 - 2.4 7.8 6.5 0.48 10.1 2.6 1.6 1 1 1 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) CytB6-F_Fe-S PF08802.10 EKX47392.1 - 3.3 7.8 6.1 4.6 7.3 0.1 2.7 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit PKD_channel PF08016.12 EKX47394.1 - 3.9e-22 78.5 35.8 1.3e-17 63.6 19.7 2.9 3 0 0 3 3 3 2 Polycystin cation channel C2 PF00168.30 EKX47394.1 - 2.6e-17 63.0 0.0 8.3e-17 61.4 0.0 1.8 1 0 0 1 1 1 1 C2 domain Ion_trans PF00520.31 EKX47394.1 - 2.4e-06 27.0 37.3 6e-05 22.4 37.3 2.4 1 1 0 1 1 1 1 Ion transport protein MMR_HSR1 PF01926.23 EKX47395.1 - 7e-16 58.3 0.0 1.2e-14 54.3 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EKX47395.1 - 1.9e-10 40.5 0.1 1.3e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EKX47395.1 - 5.2e-05 23.2 0.0 0.31 10.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EKX47395.1 - 0.0014 18.2 0.0 1.1 8.7 0.1 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 EKX47395.1 - 0.013 14.9 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 AIG1 family Roc PF08477.13 EKX47395.1 - 0.017 15.4 0.1 0.059 13.6 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EKX47395.1 - 0.032 14.3 0.1 0.42 10.7 0.0 2.4 1 1 1 2 2 2 0 Dynamin family DnaJ PF00226.31 EKX47396.1 - 3.3e-15 55.9 0.0 4.1e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 DnaJ domain HTH_16 PF12645.7 EKX47396.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain AAA PF00004.29 EKX47397.1 - 1.3e-42 145.4 0.0 5e-42 143.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EKX47397.1 - 4.8e-15 55.1 0.0 9.8e-15 54.1 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EKX47397.1 - 1.5e-08 34.5 0.8 3.3e-08 33.4 0.8 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 EKX47397.1 - 2.4e-06 27.8 0.0 5.8e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EKX47397.1 - 3.7e-06 27.4 0.1 7.9e-05 23.1 0.1 2.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EKX47397.1 - 7.6e-06 26.0 0.0 3.4e-05 23.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EKX47397.1 - 6.4e-05 23.2 0.5 0.013 15.7 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 EKX47397.1 - 0.00037 20.3 0.0 0.00068 19.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EKX47397.1 - 0.0013 18.9 0.0 0.0026 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EKX47397.1 - 0.0019 17.5 0.0 0.0039 16.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 EKX47397.1 - 0.002 18.7 0.7 0.015 15.9 0.0 2.6 3 1 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 EKX47397.1 - 0.0038 17.0 0.0 0.0081 15.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EKX47397.1 - 0.0092 15.4 0.1 0.019 14.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EKX47397.1 - 0.014 15.7 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EKX47397.1 - 0.016 14.6 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_3 PF07726.11 EKX47397.1 - 0.019 14.8 0.0 0.051 13.4 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EKX47397.1 - 0.026 14.9 0.0 0.05 14.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 EKX47397.1 - 0.03 14.1 0.0 0.078 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 EKX47397.1 - 0.041 13.9 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 EKX47397.1 - 0.044 13.2 0.0 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 EKX47397.1 - 0.045 13.3 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 EKX47397.1 - 0.049 13.3 0.0 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 EKX47397.1 - 0.055 12.6 0.0 0.095 11.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 EKX47397.1 - 0.063 12.9 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EKX47397.1 - 0.073 12.2 0.0 0.21 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 EKX47397.1 - 0.088 12.8 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2072 PF09845.9 EKX47397.1 - 0.14 12.4 0.1 0.34 11.2 0.1 1.6 1 0 0 1 1 1 0 Zn-ribbon containing protein AAA_11 PF13086.6 EKX47397.1 - 0.15 11.8 0.2 0.43 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain KLRAQ PF10205.9 EKX47397.1 - 0.32 11.3 2.8 2.1 8.7 0.2 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein RP853 PF17542.2 EKX47398.1 - 0.036 13.2 3.0 0.054 12.6 3.0 1.1 1 0 0 1 1 1 0 Uncharacterized RP853 PBP3 PF18056.1 EKX47398.1 - 0.12 12.5 0.5 0.27 11.4 0.5 1.5 1 0 0 1 1 1 0 Penicillin Binding Protein 3 Domain NAD_binding_8 PF13450.6 EKX47399.1 - 2e-08 34.3 1.9 6.4e-08 32.7 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EKX47399.1 - 1.1e-07 31.5 0.2 0.0034 16.7 0.0 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase SNF2_N PF00176.23 EKX47400.1 - 2.4e-06 26.5 0.2 8.9e-06 24.7 0.2 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain SEEEED PF14797.6 EKX47400.1 - 3.5 7.8 7.0 13 5.9 7.0 2.0 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex SNF2_N PF00176.23 EKX47401.1 - 8.4e-26 90.5 0.6 8.9e-26 90.4 0.6 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX47402.1 - 1e-08 35.5 0.0 1.2e-08 35.3 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Tecti-min-caps PF09300.10 EKX47402.1 - 0.096 12.8 0.1 0.29 11.2 0.0 1.8 1 1 1 2 2 2 0 Tectiviridae, minor capsid START PF01852.19 EKX47403.1 - 3.4e-07 29.9 0.0 4.9e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 START domain EF-hand_7 PF13499.6 EKX47404.1 - 3.4e-12 46.6 1.0 3.4e-12 46.6 1.0 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX47404.1 - 4.9e-12 44.5 6.3 1.7e-05 24.0 0.0 3.7 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 EKX47404.1 - 7.8e-09 34.6 1.5 1.1e-05 24.7 0.1 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX47404.1 - 9.3e-09 34.5 8.9 0.00077 19.2 0.0 3.9 3 1 1 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 EKX47404.1 - 1.2e-06 28.3 0.5 3.9e-06 26.6 0.2 2.0 1 1 1 2 2 2 2 EF-hand domain pair Fib_alpha PF08702.10 EKX47405.1 - 0.0022 18.2 6.4 0.0082 16.3 6.4 1.9 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family HAUS2 PF15003.6 EKX47405.1 - 0.0028 17.4 3.8 0.0054 16.5 3.8 1.5 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 2 SlyX PF04102.12 EKX47405.1 - 0.026 15.1 0.1 0.026 15.1 0.1 3.9 2 1 2 4 4 4 0 SlyX TFIIE-A_C PF11521.8 EKX47405.1 - 0.039 14.2 5.6 0.17 12.2 5.6 2.1 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha XLF PF09302.11 EKX47405.1 - 0.95 9.6 4.5 3.4 7.8 1.1 2.7 2 1 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component DUF2408 PF10303.9 EKX47405.1 - 1.2 9.7 7.2 0.81 10.2 3.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) DUF5082 PF16888.5 EKX47405.1 - 2.2 8.6 14.3 0.77 10.0 9.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) HAD_2 PF13419.6 EKX47407.1 - 6.3e-28 98.1 0.0 1.1e-27 97.3 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EKX47407.1 - 3.2e-15 57.0 0.1 6.7e-14 52.7 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EKX47407.1 - 9e-09 35.3 0.0 1.9e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EKX47407.1 - 1.1e-07 32.5 0.0 1.9e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 EKX47407.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) CBM_20 PF00686.19 EKX47408.1 - 7.5e-11 41.8 0.1 1.9e-10 40.5 0.1 1.7 1 0 0 1 1 1 1 Starch binding domain ApoLp-III PF07464.11 EKX47408.1 - 0.0049 17.0 1.9 0.0049 17.0 1.9 3.8 1 1 2 3 3 3 3 Apolipophorin-III precursor (apoLp-III) DHR10 PF18595.1 EKX47408.1 - 0.011 15.8 8.2 0.011 15.8 8.2 5.9 5 2 1 7 7 7 0 Designed helical repeat protein 10 domain Bacillus_HBL PF05791.11 EKX47408.1 - 0.19 11.5 18.1 0.28 11.0 3.2 3.4 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Baculo_PEP_C PF04513.12 EKX47408.1 - 9.6 6.2 14.8 8.5 6.4 2.6 3.7 1 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus SurA_N_3 PF13624.6 EKX47408.1 - 9.9 5.9 11.5 0.2 11.4 1.2 3.1 2 1 2 4 4 4 0 SurA N-terminal domain Ank_4 PF13637.6 EKX47409.1 - 1.9e-13 50.6 0.6 5.5e-05 23.6 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX47409.1 - 4.2e-12 46.5 0.1 1e-10 42.0 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX47409.1 - 8.2e-10 38.7 0.9 8.5e-05 22.8 0.8 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX47409.1 - 1.1e-09 38.2 0.0 0.0031 17.9 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EKX47409.1 - 2.3e-08 33.6 0.0 0.036 14.6 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat BTG PF07742.12 EKX47410.1 - 1e-16 60.8 0.1 1.6e-16 60.2 0.1 1.2 1 0 0 1 1 1 1 BTG family Iron_traffic PF04362.14 EKX47410.1 - 0.08 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking WW PF00397.26 EKX47411.1 - 1.3e-08 34.8 3.2 4.6e-08 33.0 3.2 2.1 1 0 0 1 1 1 1 WW domain Fer4_14 PF13394.6 EKX47411.1 - 0.15 12.2 0.0 0.43 10.7 0.0 1.8 1 0 0 1 1 1 0 4Fe-4S single cluster domain TPR_12 PF13424.6 EKX47412.1 - 4.2e-09 36.6 3.5 0.00066 19.9 0.1 3.1 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX47412.1 - 1e-08 34.6 4.4 0.0044 16.8 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX47412.1 - 1.4e-07 31.1 2.9 0.00014 21.6 0.5 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX47412.1 - 1e-05 25.3 4.5 0.048 13.9 0.1 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX47412.1 - 1.6e-05 24.6 4.6 0.035 14.2 0.5 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX47412.1 - 0.00077 19.7 0.1 0.031 14.6 0.1 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat DUF4041 PF13250.6 EKX47412.1 - 0.00097 19.0 0.6 0.006 16.4 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4041) TPR_7 PF13176.6 EKX47412.1 - 0.0061 16.5 5.0 0.0097 15.9 0.3 3.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Clathrin PF00637.20 EKX47412.1 - 0.021 14.7 0.7 0.68 9.8 0.0 2.2 1 1 0 2 2 2 0 Region in Clathrin and VPS MIT PF04212.18 EKX47412.1 - 0.028 14.5 0.8 0.68 10.0 0.0 2.8 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain Ion_trans PF00520.31 EKX47413.1 - 3.3e-10 39.6 12.3 4.4e-09 35.9 12.3 2.0 1 1 0 1 1 1 1 Ion transport protein PH PF00169.29 EKX47413.1 - 5.9e-06 26.7 0.0 9e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 PH domain EF-hand_1 PF00036.32 EKX47414.1 - 0.0022 17.4 0.1 0.011 15.3 0.0 2.3 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 EKX47414.1 - 0.011 15.6 0.1 0.1 12.6 0.0 2.5 3 0 0 3 3 3 0 EF-hand domain Ion_trans PF00520.31 EKX47414.1 - 0.041 13.1 0.1 0.058 12.6 0.1 1.2 1 0 0 1 1 1 0 Ion transport protein EF-hand_7 PF13499.6 EKX47414.1 - 0.045 14.2 0.3 0.53 10.8 0.0 2.8 2 1 0 2 2 2 0 EF-hand domain pair Xpo1 PF08389.12 EKX47414.1 - 0.12 12.4 5.9 0.2 11.7 1.3 2.2 2 0 0 2 2 2 0 Exportin 1-like protein YpzI PF14140.6 EKX47414.1 - 8.6 6.2 8.1 11 5.8 0.0 3.0 3 0 0 3 3 3 0 YpzI-like protein RCC1_2 PF13540.6 EKX47415.1 - 2.6e-08 33.4 3.4 1.4e-05 24.7 1.1 5.5 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat Rieske PF00355.26 EKX47416.1 - 2.8e-13 49.6 0.1 5e-13 48.8 0.1 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 EKX47416.1 - 9.3e-09 35.2 0.0 1.4e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain WD40 PF00400.32 EKX47417.1 - 1.7e-11 44.4 16.9 0.069 14.0 0.1 8.6 10 0 0 10 10 10 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX47417.1 - 1.1e-07 32.1 0.7 0.071 13.4 0.0 5.8 5 1 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_7 PF13499.6 EKX47417.1 - 1.7e-05 25.1 0.8 0.052 14.0 0.0 3.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX47417.1 - 2e-05 23.8 0.1 0.01 15.3 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX47417.1 - 7.2e-05 22.6 0.3 0.0042 16.9 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX47417.1 - 0.00012 21.4 0.5 0.0004 19.7 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EKX47417.1 - 0.0073 16.2 0.1 0.28 11.2 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain DEAD PF00270.29 EKX47418.1 - 1.8e-19 70.2 0.0 3.8e-19 69.1 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX47418.1 - 5.3e-16 58.9 0.0 1.4e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HRDC PF00570.23 EKX47418.1 - 8e-15 54.6 0.2 2.3e-14 53.1 0.0 2.0 2 0 0 2 2 2 1 HRDC domain RecQ_Zn_bind PF16124.5 EKX47418.1 - 1.3e-11 45.0 1.1 2.8e-11 43.9 1.1 1.5 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 EKX47418.1 - 2.4e-11 43.4 0.0 1.1e-09 38.1 0.0 2.6 2 0 0 2 2 2 1 RQC domain ResIII PF04851.15 EKX47418.1 - 2.2e-05 24.5 0.0 4.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF5046 PF16465.5 EKX47418.1 - 0.031 13.7 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5046) Thi4 PF01946.17 EKX47419.1 - 2e-105 351.3 0.1 2.3e-105 351.0 0.1 1.0 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EKX47419.1 - 8.1e-09 35.5 1.8 2.6e-07 30.6 0.9 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EKX47419.1 - 4.6e-07 30.0 0.1 1.5e-06 28.3 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EKX47419.1 - 1.3e-06 27.8 2.2 7.7e-05 21.9 1.4 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EKX47419.1 - 7.6e-06 25.4 0.2 1.5e-05 24.3 0.2 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EKX47419.1 - 9.2e-05 21.7 0.1 0.00014 21.0 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 EKX47419.1 - 0.00064 18.5 0.7 0.0018 17.0 0.6 1.7 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 EKX47419.1 - 0.0007 19.6 0.5 0.0027 17.7 0.1 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EKX47419.1 - 0.0031 16.8 0.0 0.0052 16.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EKX47419.1 - 0.0077 16.8 1.7 0.023 15.3 0.2 2.5 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EKX47419.1 - 0.022 14.1 0.6 0.052 12.9 0.1 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 EKX47419.1 - 0.032 13.3 0.7 0.059 12.4 0.3 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EKX47419.1 - 0.051 12.8 0.1 0.086 12.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain FMO-like PF00743.19 EKX47419.1 - 0.062 11.7 0.0 0.087 11.2 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Trp_halogenase PF04820.14 EKX47419.1 - 0.1 11.5 0.3 0.16 10.8 0.3 1.3 1 0 0 1 1 1 0 Tryptophan halogenase K_oxygenase PF13434.6 EKX47419.1 - 0.15 11.1 0.1 0.35 9.9 0.0 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Glycos_transf_2 PF00535.26 EKX47420.1 - 2.4e-09 37.2 0.0 7.8e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Dynactin_p22 PF07426.11 EKX47420.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Dynactin subunit p22 Acyl_transf_1 PF00698.21 EKX47423.1 - 1.1e-25 90.8 0.2 1.4e-25 90.5 0.2 1.1 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 EKX47423.1 - 0.00076 19.3 0.1 0.018 14.8 0.1 2.2 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis DUF3088 PF11287.8 EKX47423.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3088) VKOR PF07884.14 EKX47425.1 - 1.4e-14 54.4 12.0 2.1e-14 53.7 12.0 1.3 1 0 0 1 1 1 1 Vitamin K epoxide reductase family 7tm_1 PF00001.21 EKX47425.1 - 0.012 14.9 0.2 0.017 14.5 0.2 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Fra10Ac1 PF09725.9 EKX47426.1 - 2.8e-47 159.9 4.7 4.1e-47 159.3 4.7 1.2 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 DUF977 PF06163.11 EKX47426.1 - 0.025 14.5 0.4 0.049 13.6 0.3 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF977) Cyclin_C PF02984.19 EKX47427.1 - 2.1e-12 47.2 3.8 3e-11 43.4 3.2 2.2 1 1 1 2 2 2 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 EKX47427.1 - 1e-11 44.6 0.8 8.5e-11 41.7 0.1 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain SbsC_C PF18058.1 EKX47427.1 - 0.012 15.9 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 SbsC C-terminal domain NAC PF01849.18 EKX47428.1 - 8.9e-25 86.4 2.1 2.9e-24 84.8 0.8 2.2 2 0 0 2 2 2 1 NAC domain CENP-C_C PF11699.8 EKX47428.1 - 0.013 15.7 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 Mif2/CENP-C like VIGSSK PF14773.6 EKX47428.1 - 0.13 12.4 0.4 0.13 12.4 0.4 2.6 3 0 0 3 3 3 0 Helicase-associated putative binding domain, C-terminal PGA2 PF07543.12 EKX47428.1 - 0.14 12.1 11.5 1.1 9.3 1.6 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 PBP1_TM PF14812.6 EKX47428.1 - 1.4 9.3 15.5 0.83 10.1 7.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 EKX47428.1 - 3.4 7.3 16.5 4.7 6.9 5.5 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Thioredoxin PF00085.20 EKX47429.1 - 4.7e-05 23.3 0.0 0.1 12.6 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin DHHC PF01529.20 EKX47430.1 - 3.3e-25 88.7 10.2 3.5e-25 88.6 10.2 1.0 1 0 0 1 1 1 1 DHHC palmitoyltransferase WD40 PF00400.32 EKX47431.1 - 7e-11 42.5 0.2 0.0067 17.3 0.0 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX47431.1 - 3.3e-07 30.5 0.0 1.2 9.5 0.0 4.4 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Pro-NT_NN PF07421.11 EKX47431.1 - 0.22 11.8 3.4 0.62 10.3 3.4 1.7 1 0 0 1 1 1 0 Neurotensin/neuromedin N precursor Mic1 PF07035.12 EKX47432.1 - 5.9e-37 126.8 0.0 1.2e-36 125.8 0.0 1.5 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like Topoisom_bac PF01131.20 EKX47433.1 - 3.5e-93 312.9 0.0 5.1e-93 312.3 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EKX47433.1 - 6.2e-13 48.9 0.0 1.2e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Toprim domain FXMRP1_C_core PF12235.8 EKX47433.1 - 0.02 15.6 0.3 0.041 14.5 0.3 1.5 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal Zip PF02535.22 EKX47434.1 - 0.11 11.7 7.8 0.15 11.3 7.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Orf78 PF06024.12 EKX47434.1 - 0.16 12.3 0.3 0.16 12.3 0.3 1.7 1 1 1 2 2 2 0 Orf78 (ac78) MIF4G_like_2 PF09090.11 EKX47434.1 - 5.5 6.4 11.0 6.3 6.2 11.0 1.0 1 0 0 1 1 1 0 MIF4G like DUF3669 PF12417.8 EKX47435.1 - 0.1 12.8 0.5 0.89 9.8 0.0 2.4 2 0 0 2 2 2 0 Zinc finger protein Ephrin_rec_like PF07699.13 EKX47436.1 - 1.1e-06 28.3 1.4 1.1e-06 28.3 1.4 2.5 2 1 0 2 2 2 1 Putative ephrin-receptor like PKD_channel PF08016.12 EKX47437.1 - 1.6e-31 109.5 8.0 2.3e-31 108.9 8.0 1.2 1 0 0 1 1 1 1 Polycystin cation channel PH PF00169.29 EKX47437.1 - 1e-05 26.0 0.2 2.5e-05 24.7 0.2 1.7 1 0 0 1 1 1 1 PH domain Herpes_BLRF2 PF05812.12 EKX47437.1 - 0.17 12.0 0.1 0.36 11.0 0.1 1.5 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein bZIP_2 PF07716.15 EKX47437.1 - 2.2 8.5 4.6 1.4 9.1 0.4 2.3 2 0 0 2 2 2 0 Basic region leucine zipper OPA3 PF07047.12 EKX47439.1 - 6.7e-28 97.0 0.4 7.4e-28 96.8 0.4 1.0 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) HalX PF08663.10 EKX47440.1 - 1.9 8.8 10.9 5.7 7.3 6.2 3.0 2 1 0 2 2 2 0 HalX domain ATP-gua_Ptrans PF00217.19 EKX47441.1 - 3.1e-67 226.1 0.0 5.2e-67 225.4 0.0 1.3 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 EKX47441.1 - 2.2e-18 66.4 0.0 3.9e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 ATP:guanido phosphotransferase, N-terminal domain ABC_tran PF00005.27 EKX47442.1 - 3.1e-10 40.7 0.0 9.2e-10 39.2 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EKX47442.1 - 0.00052 19.9 0.0 0.00071 19.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 EKX47442.1 - 0.026 14.5 0.6 0.039 14.0 0.6 1.1 1 0 0 1 1 1 0 ABC transporter U-box PF04564.15 EKX47443.1 - 2.4e-19 69.3 0.0 2.5e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX47443.1 - 1e-06 28.5 0.0 1.4e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EKX47443.1 - 1.5e-05 24.9 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EKX47443.1 - 0.017 15.0 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-NOSIP PF15906.5 EKX47443.1 - 0.068 13.3 0.0 0.096 12.8 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-rbx1 PF12678.7 EKX47443.1 - 0.077 13.3 0.1 0.15 12.3 0.0 1.6 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EKX47443.1 - 0.12 12.5 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Pkinase_Tyr PF07714.17 EKX47444.1 - 8e-59 199.0 0.0 9.5e-59 198.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX47444.1 - 4.1e-34 118.1 0.0 4.9e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EKX47444.1 - 0.0097 14.7 0.0 0.018 13.8 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase WEMBL PF05701.11 EKX47445.1 - 0.0005 18.9 15.6 0.00069 18.4 15.6 1.3 1 0 0 1 1 1 1 Weak chloroplast movement under blue light PEARLI-4 PF05278.12 EKX47445.1 - 0.0011 18.7 15.0 0.019 14.6 2.4 2.5 1 1 1 2 2 2 2 Arabidopsis phospholipase-like protein (PEARLI 4) TBK1_CCD1 PF18394.1 EKX47445.1 - 0.0018 17.9 6.3 0.037 13.6 1.4 2.1 1 1 1 2 2 2 1 TANK-binding kinase 1 coiled-coil domain 1 PI3K_P85_iSH2 PF16454.5 EKX47445.1 - 0.0047 16.5 7.2 0.057 13.0 7.2 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Spc7 PF08317.11 EKX47445.1 - 0.0057 15.6 17.4 0.014 14.3 12.1 1.8 1 1 0 1 1 1 1 Spc7 kinetochore protein Fez1 PF06818.15 EKX47445.1 - 0.0065 17.0 14.4 0.039 14.4 14.4 1.9 1 1 0 1 1 1 1 Fez1 CheZ PF04344.13 EKX47445.1 - 0.011 15.7 5.2 0.1 12.5 5.0 2.0 1 1 0 1 1 1 0 Chemotaxis phosphatase, CheZ Sugarporin_N PF11471.8 EKX47445.1 - 0.012 15.6 10.5 0.096 12.7 0.8 2.9 2 1 1 3 3 3 0 Maltoporin periplasmic N-terminal extension ATG16 PF08614.11 EKX47445.1 - 0.012 15.8 18.7 0.04 14.1 18.7 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 EKX47445.1 - 0.012 15.1 12.4 0.016 14.7 12.4 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 FPP PF05911.11 EKX47445.1 - 0.017 13.4 14.4 0.019 13.2 14.4 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Sh_2 PF17512.2 EKX47445.1 - 0.017 14.9 1.7 0.34 10.7 0.2 2.2 1 1 1 2 2 2 0 Metapneumovirus Small hydrophobic protein Lebercilin PF15619.6 EKX47445.1 - 0.023 14.4 15.9 0.16 11.6 15.9 2.3 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Myosin_tail_1 PF01576.19 EKX47445.1 - 0.023 12.5 15.2 0.026 12.4 15.2 1.0 1 0 0 1 1 1 0 Myosin tail Filament PF00038.21 EKX47445.1 - 0.026 14.1 11.7 0.079 12.5 11.5 1.7 1 1 0 1 1 1 0 Intermediate filament protein Atg14 PF10186.9 EKX47445.1 - 0.031 13.4 12.1 0.28 10.2 11.6 2.0 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4200 PF13863.6 EKX47445.1 - 0.041 14.3 14.2 0.38 11.1 6.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) COG2 PF06148.11 EKX47445.1 - 0.042 13.9 9.0 0.97 9.5 2.7 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4201 PF13870.6 EKX47445.1 - 0.043 13.5 16.0 0.09 12.5 8.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) HAP1_N PF04849.13 EKX47445.1 - 0.048 12.9 10.4 0.069 12.3 10.4 1.3 1 1 0 1 1 1 0 HAP1 N-terminal conserved region HMMR_N PF15905.5 EKX47445.1 - 0.052 13.0 14.2 0.063 12.7 14.2 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal RT_RNaseH PF17917.1 EKX47445.1 - 0.076 13.3 1.1 1 9.7 0.2 2.1 1 1 1 2 2 2 0 RNase H-like domain found in reverse transcriptase Lectin_N PF03954.14 EKX47445.1 - 0.12 12.1 7.2 0.45 10.2 1.0 2.2 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Fea1 PF07692.11 EKX47445.1 - 0.12 11.3 1.1 0.18 10.8 0.4 1.6 1 1 1 2 2 2 0 Low iron-inducible periplasmic protein APG6_N PF17675.1 EKX47445.1 - 0.15 12.6 20.4 0.33 11.5 17.3 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region Sec2p PF06428.11 EKX47445.1 - 0.16 12.0 14.2 0.55 10.2 2.5 2.9 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Sec34 PF04136.15 EKX47445.1 - 0.16 11.8 7.0 2.3 8.1 1.1 2.2 1 1 1 2 2 2 0 Sec34-like family TPR_MLP1_2 PF07926.12 EKX47445.1 - 0.2 11.7 18.0 6.6 6.8 18.0 2.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein zf-C4H2 PF10146.9 EKX47445.1 - 0.25 11.6 11.3 0.3 11.4 11.3 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein Matrilin_ccoil PF10393.9 EKX47445.1 - 0.27 11.1 8.0 5.2 7.0 0.2 3.7 3 1 1 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin IFT57 PF10498.9 EKX47445.1 - 0.29 10.0 11.5 0.4 9.6 11.5 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DegS PF05384.11 EKX47445.1 - 0.31 10.5 11.2 0.8 9.2 10.8 1.8 1 1 1 2 2 2 0 Sensor protein DegS DUF4763 PF15960.5 EKX47445.1 - 0.32 10.3 8.7 1.4 8.1 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) NBP1 PF08537.10 EKX47445.1 - 0.35 10.2 11.5 1.1 8.6 11.5 1.7 1 1 0 1 1 1 0 Fungal Nap binding protein NBP1 DUF3552 PF12072.8 EKX47445.1 - 0.39 10.1 17.2 0.97 8.8 3.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) ADIP PF11559.8 EKX47445.1 - 0.84 9.7 15.4 2.4 8.2 6.3 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding SPATA1_C PF15743.5 EKX47445.1 - 0.99 9.5 13.9 2.6 8.1 10.9 2.2 1 1 1 2 2 2 0 Spermatogenesis-associated C-terminus DUF3053 PF11254.8 EKX47445.1 - 1 8.9 7.3 4.4 6.8 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) Mod_r PF07200.13 EKX47445.1 - 1.2 9.3 12.3 5.2 7.2 5.6 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Strep_SA_rep PF06696.11 EKX47445.1 - 1.2 9.2 8.8 4.8 7.3 0.2 4.4 5 0 0 5 5 5 0 Streptococcal surface antigen repeat DUF1664 PF07889.12 EKX47445.1 - 1.2 9.2 8.9 2.9 8.0 4.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FapA PF03961.13 EKX47445.1 - 1.3 7.6 9.5 1.9 7.0 9.5 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A CENP-H PF05837.12 EKX47445.1 - 1.5 9.3 16.8 3.3 8.2 7.0 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Spc24 PF08286.11 EKX47445.1 - 1.6 9.0 16.3 4.6 7.5 3.0 2.7 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 BRE1 PF08647.11 EKX47445.1 - 1.6 8.8 17.7 6.6 6.9 7.6 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Uso1_p115_C PF04871.13 EKX47445.1 - 1.7 9.0 18.4 24 5.3 18.4 2.0 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DLP_helical PF18709.1 EKX47445.1 - 2.1 7.5 10.6 1.5 8.0 2.6 2.2 1 1 1 2 2 2 0 Dynamin-like helical domain KELK PF15796.5 EKX47445.1 - 2.2 8.8 13.9 6.1 7.4 3.6 2.9 1 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Sec8_exocyst PF04048.14 EKX47445.1 - 2.2 8.1 10.7 6.8 6.6 1.2 3.1 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain AAA_13 PF13166.6 EKX47445.1 - 2.3 6.7 13.6 7 5.2 13.6 1.6 1 1 0 1 1 1 0 AAA domain Syntaxin-6_N PF09177.11 EKX47445.1 - 2.4 8.8 10.9 6.9 7.3 4.4 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal UPF0242 PF06785.11 EKX47445.1 - 2.6 8.1 14.0 7.1 6.7 14.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HAUS-augmin3 PF14932.6 EKX47445.1 - 3.3 7.2 11.9 7.7 6.0 12.0 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 FlaC_arch PF05377.11 EKX47445.1 - 4.4 7.8 10.7 7.8 7.0 0.3 3.5 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) LMBR1 PF04791.16 EKX47445.1 - 4.6 6.0 6.4 5.3 5.8 6.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Metal_resist PF13801.6 EKX47445.1 - 5.3 7.3 7.0 17 5.6 0.8 2.4 1 1 0 2 2 2 0 Heavy-metal resistance Nup54 PF13874.6 EKX47445.1 - 5.4 7.1 10.2 9.9 6.3 9.6 1.7 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 TMF_DNA_bd PF12329.8 EKX47445.1 - 6 6.9 21.5 2.2 8.4 8.3 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding YabA PF06156.13 EKX47445.1 - 7.9 7.2 11.5 6.8 7.4 5.2 2.1 1 1 1 2 2 2 0 Initiation control protein YabA 2OG-FeII_Oxy_3 PF13640.6 EKX47446.1 - 7.6e-14 52.4 0.0 1.2e-13 51.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EKX47446.1 - 0.0009 19.7 0.1 0.0078 16.7 0.0 2.4 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily FSH1 PF03959.13 EKX47446.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Fis1_TPR_C PF14853.6 EKX47447.1 - 8.2e-16 57.8 1.5 1.5e-15 56.9 1.5 1.5 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 EKX47447.1 - 1.4e-06 27.8 0.0 3.1e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_19 PF14559.6 EKX47447.1 - 0.00025 21.5 3.1 0.00049 20.5 3.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX47447.1 - 0.0011 19.4 6.1 0.0028 18.2 1.3 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX47447.1 - 0.0029 17.6 1.1 0.0029 17.6 1.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX47447.1 - 0.0054 16.5 1.2 0.0054 16.5 1.2 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX47447.1 - 0.014 15.7 0.9 12 6.6 0.6 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX47447.1 - 0.051 13.8 4.2 0.1 12.8 0.9 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 NTPase_I-T PF01931.18 EKX47447.1 - 0.11 12.2 0.0 0.26 11.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF84 TPR_14 PF13428.6 EKX47447.1 - 0.33 11.9 4.9 0.3 12.0 1.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EKX47447.1 - 1.4 8.6 6.0 6.8 6.5 0.1 2.9 3 0 0 3 3 3 0 TPR repeat TPR_1 PF00515.28 EKX47448.1 - 2.6e-26 90.3 40.2 2.6e-06 27.0 0.0 12.4 14 1 1 15 15 14 6 Tetratricopeptide repeat TPR_2 PF07719.17 EKX47448.1 - 3.5e-24 82.9 37.7 0.0027 17.7 0.0 12.6 14 0 0 14 14 12 7 Tetratricopeptide repeat TPR_12 PF13424.6 EKX47448.1 - 8.2e-21 74.1 27.5 2.1e-08 34.3 0.0 9.7 7 3 3 11 11 11 7 Tetratricopeptide repeat TPR_8 PF13181.6 EKX47448.1 - 8.4e-18 63.0 33.4 0.051 13.8 0.1 12.5 12 1 0 12 12 12 7 Tetratricopeptide repeat TPR_7 PF13176.6 EKX47448.1 - 1.1e-16 59.5 11.7 0.015 15.3 0.0 9.6 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX47448.1 - 1.4e-16 60.8 10.4 0.0083 16.7 0.0 8.1 8 1 0 8 8 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 EKX47448.1 - 1.7e-15 57.3 22.2 0.00085 19.8 0.0 8.7 7 2 3 10 10 9 5 Tetratricopeptide repeat TPR_6 PF13174.6 EKX47448.1 - 7.2e-14 51.4 27.1 0.29 11.9 0.0 10.6 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 EKX47448.1 - 9.6e-14 50.9 5.1 0.36 11.8 0.0 9.9 8 3 3 11 11 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX47448.1 - 2.8e-09 36.5 21.8 0.0031 17.1 0.0 8.8 9 2 1 10 10 10 3 TPR repeat TPR_9 PF13371.6 EKX47448.1 - 8.9e-06 25.8 1.2 1.5 9.0 0.0 4.5 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX47448.1 - 0.00015 21.9 16.5 33 5.2 1.0 9.3 7 2 1 8 8 8 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX47448.1 - 0.00033 20.8 18.6 0.009 16.2 0.5 5.9 5 2 1 7 7 6 2 Anaphase-promoting complex, cyclosome, subunit 3 Sel1 PF08238.12 EKX47448.1 - 0.1 13.3 4.1 8.6 7.2 0.3 4.8 4 1 1 5 5 3 0 Sel1 repeat TPR_10 PF13374.6 EKX47448.1 - 0.4 10.6 0.0 0.4 10.6 0.0 8.4 11 0 0 11 11 11 0 Tetratricopeptide repeat MIT PF04212.18 EKX47448.1 - 3.9 7.6 36.0 2.7 8.1 0.6 9.5 11 0 0 11 11 10 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 EKX47450.1 - 1e-18 66.3 9.6 0.00064 19.4 0.0 7.8 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 EKX47450.1 - 4e-18 64.0 15.3 0.0024 17.8 0.1 7.7 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 EKX47450.1 - 5.9e-18 63.5 2.5 0.075 13.3 0.0 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 EKX47450.1 - 1e-16 61.2 13.7 2.1e-06 28.1 2.3 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX47450.1 - 6.1e-16 57.2 3.5 0.29 11.3 0.0 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 EKX47450.1 - 1.5e-14 54.1 12.7 0.0026 18.0 2.9 6.3 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 EKX47450.1 - 4.3e-14 52.9 13.3 1.2e-07 32.3 4.6 5.6 5 1 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX47450.1 - 4.8e-14 51.8 18.6 0.05 14.4 0.1 7.9 5 1 3 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 EKX47450.1 - 3.3e-05 23.5 8.3 0.24 11.1 0.0 5.9 5 1 3 8 8 8 2 TPR repeat TPR_10 PF13374.6 EKX47450.1 - 4.5e-05 23.2 21.3 0.3 11.0 0.4 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_20 PF14561.6 EKX47450.1 - 4.6e-05 23.7 4.9 0.044 14.1 0.4 3.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 EKX47450.1 - 0.00016 21.0 13.2 0.071 12.3 6.3 4.3 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX47450.1 - 0.00032 20.9 10.0 0.19 12.2 0.1 5.6 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX47450.1 - 0.002 18.2 4.6 0.01 15.9 1.5 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat Imm51 PF15595.6 EKX47450.1 - 0.003 17.5 0.1 0.0075 16.2 0.1 1.6 1 0 0 1 1 1 1 Immunity protein 51 TPR_21 PF09976.9 EKX47450.1 - 0.0038 16.9 2.5 31 4.2 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 EKX47450.1 - 0.13 12.6 9.6 0.099 12.9 0.8 3.8 3 2 1 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 EKX47450.1 - 1.8 9.4 10.8 6.6 7.7 0.2 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat RAP PF08373.10 EKX47451.1 - 0.0012 18.9 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 RAP domain MTES_1575 PF18741.1 EKX47451.1 - 0.0074 16.4 0.1 0.052 13.7 0.1 2.0 1 1 0 1 1 1 1 REase_MTES_1575 Helicase_C PF00271.31 EKX47455.1 - 9.2e-05 22.8 0.1 0.00043 20.6 0.1 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF5338 PF17273.2 EKX47455.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5338) Peptidase_M32 PF02074.15 EKX47455.1 - 0.14 10.9 0.2 0.18 10.5 0.2 1.0 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase CENP-T_C PF15511.6 EKX47455.1 - 0.15 12.2 0.1 2.3 8.4 0.1 2.1 1 1 0 2 2 2 0 Centromere kinetochore component CENP-T histone fold PolyA_pol PF01743.20 EKX47456.1 - 0.023 15.1 1.4 3.9 7.9 0.0 2.9 2 0 0 2 2 2 0 Poly A polymerase head domain DUF3841 PF12952.7 EKX47456.1 - 0.92 9.3 5.0 4.1 7.2 1.8 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3841) FAM76 PF16046.5 EKX47456.1 - 4.9 6.4 15.1 0.097 12.0 6.5 2.1 1 1 1 2 2 2 0 FAM76 protein MFS_1_like PF12832.7 EKX47457.1 - 0.018 13.9 0.2 0.02 13.8 0.2 1.1 1 0 0 1 1 1 0 MFS_1 like family HC2 PF07382.11 EKX47458.1 - 1.2e-07 32.0 168.4 1.3e-05 25.4 81.4 3.7 2 1 2 4 4 4 3 Histone H1-like nucleoprotein HC2 TUDOR_5 PF18359.1 EKX47458.1 - 3.9e-05 23.3 0.4 0.0049 16.6 0.2 3.0 3 0 0 3 3 3 1 Histone methyltransferase Tudor domain 1 Tudor_3 PF18115.1 EKX47458.1 - 0.00084 19.1 0.3 0.18 11.7 0.1 2.8 2 1 0 2 2 2 2 DNA repair protein Crb2 Tudor domain AIDA PF16168.5 EKX47458.1 - 0.061 13.4 1.0 0.28 11.3 0.2 2.3 2 0 0 2 2 2 0 Adhesin of bacterial autotransporter system, probable stalk PriA_3primeBD PF17764.1 EKX47458.1 - 0.12 12.3 1.1 13 5.8 0.1 2.6 2 0 0 2 2 2 0 3′ DNA-binding domain (3′BD) Topoisom_bac PF01131.20 EKX47459.1 - 1.2e-112 377.0 0.0 1.5e-112 376.7 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EKX47459.1 - 1.1e-14 54.5 0.0 2.1e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Toprim domain ubiquitin PF00240.23 EKX47460.1 - 1.8e-09 37.2 6.9 0.0019 17.9 0.0 5.2 5 0 0 5 5 5 3 Ubiquitin family DUF2407 PF10302.9 EKX47460.1 - 6.7e-07 29.8 23.8 0.00011 22.7 0.2 5.8 5 1 1 6 6 6 3 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EKX47460.1 - 0.00099 19.2 15.4 0.0024 18.0 0.1 5.2 3 1 2 5 5 5 2 Ubiquitin-2 like Rad60 SUMO-like ESP PF16590.5 EKX47460.1 - 0.32 11.3 4.9 0.18 12.1 0.7 2.8 2 0 0 2 2 2 0 Exocrine gland-secreting peptide SAM_1 PF00536.30 EKX47462.1 - 3.1e-15 56.3 0.1 7.8e-15 55.1 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EKX47462.1 - 3.9e-15 55.7 0.6 8.3e-15 54.7 0.2 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PX PF00787.24 EKX47462.1 - 9.6e-13 48.1 0.0 1.9e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 PX domain PDZ_6 PF17820.1 EKX47462.1 - 3.8e-12 45.8 0.3 8.1e-12 44.8 0.3 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX47462.1 - 4.2e-07 30.2 0.0 9.7e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX47462.1 - 5.9e-06 26.5 0.0 1.4e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain SAM_Ste50p PF09235.10 EKX47462.1 - 0.019 15.2 0.4 0.047 13.9 0.1 1.8 2 0 0 2 2 2 0 Ste50p, sterile alpha motif Tricorn_PDZ PF14685.6 EKX47462.1 - 0.063 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain SAM_4 PF18017.1 EKX47462.1 - 0.2 11.6 0.1 0.46 10.5 0.1 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) EF-hand_6 PF13405.6 EKX47463.1 - 5.1e-05 22.9 0.2 0.00013 21.6 0.2 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 EKX47463.1 - 0.00041 19.7 0.1 0.0013 18.1 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EKX47463.1 - 0.0049 17.3 0.4 0.0049 17.3 0.4 2.8 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX47463.1 - 0.0056 16.1 0.1 0.018 14.5 0.1 1.9 1 0 0 1 1 1 1 EF hand CCDC53 PF10152.9 EKX47464.1 - 0.41 11.0 6.2 0.59 10.5 4.9 1.9 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Fib_alpha PF08702.10 EKX47464.1 - 3 8.0 16.1 6.8 6.9 6.1 4.0 3 3 1 4 4 4 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.7 EKX47464.1 - 6.5 6.9 27.1 5.5 7.1 1.3 4.0 3 1 1 4 4 4 0 Tropomyosin like FHA PF00498.26 EKX47465.1 - 9e-11 42.0 0.0 1.6e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EKX47465.1 - 0.0039 17.5 0.0 0.0098 16.2 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain PH PF00169.29 EKX47465.1 - 0.0098 16.4 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 1 PH domain TFIIA PF03153.13 EKX47467.1 - 1 9.3 13.8 1.2 9.0 13.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2981 PF11200.8 EKX47467.1 - 1.2 8.8 3.9 1.5 8.5 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) HAP1_N PF04849.13 EKX47468.1 - 0.0072 15.6 1.6 0.012 14.8 1.6 1.3 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Takusan PF04822.13 EKX47468.1 - 0.016 15.1 0.4 0.032 14.1 0.4 1.5 1 0 0 1 1 1 0 Takusan ATPase PF06745.13 EKX47468.1 - 0.067 12.5 0.2 0.11 11.9 0.2 1.2 1 0 0 1 1 1 0 KaiC TFIIA PF03153.13 EKX47468.1 - 0.77 9.7 6.6 1 9.3 6.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SGT1 PF07093.11 EKX47468.1 - 5.6 5.3 8.8 6.5 5.1 4.6 2.1 2 0 0 2 2 2 0 SGT1 protein Methyltransf_23 PF13489.6 EKX47469.1 - 0.00059 19.7 0.0 0.00069 19.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX47469.1 - 0.0016 18.2 0.1 0.0023 17.8 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX47469.1 - 0.0024 18.5 0.1 0.018 15.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 EKX47469.1 - 0.0039 17.2 0.0 0.0047 16.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX47469.1 - 0.01 16.5 0.1 0.018 15.7 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain AdoMet_MTase PF07757.13 EKX47469.1 - 0.019 15.3 0.0 0.021 15.1 0.0 1.2 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase TPMT PF05724.11 EKX47469.1 - 0.1 12.2 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 EKX47469.1 - 0.13 11.8 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase small domain MetW PF07021.12 EKX47469.1 - 0.16 11.5 0.0 0.21 11.2 0.0 1.1 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW CLIP_SPH_mas PF18398.1 EKX47473.1 - 1.3 9.5 0.0 1.3 9.5 0.0 2.3 2 1 0 2 2 2 0 Clip-domain serine protease homolog masquerade Methyltransf_21 PF05050.12 EKX47474.1 - 2.4e-13 50.5 0.0 3.4e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Glyco_transf_8 PF01501.20 EKX47475.1 - 1.4e-23 83.7 0.7 1.9e-23 83.4 0.7 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EKX47475.1 - 0.00072 19.0 0.3 0.0071 15.7 0.1 2.3 2 1 0 2 2 2 1 Mannosyltransferase putative MFS_1 PF07690.16 EKX47476.1 - 5.4e-33 114.4 39.4 5.4e-33 114.4 39.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EKX47476.1 - 1.2e-05 24.3 10.7 0.00025 20.0 10.7 3.0 1 1 0 1 1 1 1 MFS_1 like family tRNA-synt_1 PF00133.22 EKX47477.1 - 1.7e-210 700.4 0.0 2.4e-210 699.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EKX47477.1 - 2.9e-29 102.0 0.7 5.7e-29 101.0 0.2 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EKX47477.1 - 2.5e-14 52.8 3.0 0.0007 18.4 0.0 4.3 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EKX47477.1 - 1.5e-05 24.6 0.0 3.4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain CHB_HEX PF03173.13 EKX47477.1 - 0.06 13.0 0.1 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 Putative carbohydrate binding domain Nucleopor_Nup85 PF07575.13 EKX47478.1 - 5.2e-31 107.8 1.3 2.1e-30 105.8 1.3 1.7 1 1 0 1 1 1 1 Nup85 Nucleoporin Bromodomain PF00439.25 EKX47479.1 - 2.4e-17 62.7 0.0 2.8e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Bromodomain Bromodomain PF00439.25 EKX47480.1 - 1.8e-21 76.0 0.1 2e-21 75.8 0.1 1.0 1 0 0 1 1 1 1 Bromodomain DUF3313 PF11769.8 EKX47480.1 - 0.15 11.9 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3313) Bromodomain PF00439.25 EKX47481.1 - 6.3e-18 64.6 0.0 6.8e-18 64.5 0.0 1.0 1 0 0 1 1 1 1 Bromodomain IGPS PF00218.21 EKX47482.1 - 1.7e-07 30.6 0.4 2.8e-07 30.0 0.4 1.4 1 1 0 1 1 1 1 Indole-3-glycerol phosphate synthase UBA PF00627.31 EKX47483.1 - 6.3e-15 54.7 13.5 5e-14 51.9 0.7 4.0 4 0 0 4 4 4 2 UBA/TS-N domain STI1 PF17830.1 EKX47483.1 - 3.5e-07 30.0 2.1 7.6e-07 29.0 2.1 1.5 1 0 0 1 1 1 1 STI1 domain ubiquitin PF00240.23 EKX47483.1 - 1.3e-06 28.1 0.0 3.8e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin family DUF4258 PF14076.6 EKX47483.1 - 0.039 14.3 1.0 7.8 7.0 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4258) TetR_C_1 PF02909.17 EKX47483.1 - 0.05 13.4 0.2 0.05 13.4 0.2 2.6 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain CUE PF02845.16 EKX47483.1 - 0.062 13.0 0.0 0.062 13.0 0.0 3.4 3 1 0 3 3 3 0 CUE domain Adhes-Ig_like PF09085.10 EKX47483.1 - 0.091 12.9 0.4 0.091 12.9 0.4 3.3 2 1 1 3 3 3 0 Adhesion molecule, immunoglobulin-like SID-1_RNA_chan PF13965.6 EKX47483.1 - 0.098 11.1 0.4 0.14 10.5 0.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PDZ_6 PF17820.1 EKX47485.1 - 1.2e-29 101.9 7.9 9.9e-10 38.1 0.0 7.3 8 0 0 8 8 8 5 PDZ domain PDZ_2 PF13180.6 EKX47485.1 - 3.1e-26 91.5 2.4 5.4e-06 26.6 0.1 6.0 5 0 0 5 5 5 5 PDZ domain PDZ PF00595.24 EKX47485.1 - 4.4e-24 84.6 7.0 4e-06 27.1 0.1 5.4 5 0 0 5 5 5 4 PDZ domain Tricorn_PDZ PF14685.6 EKX47485.1 - 6.5e-06 26.0 1.6 3.7 7.6 0.0 6.0 4 1 0 4 4 4 2 Tricorn protease PDZ domain GRASP55_65 PF04495.14 EKX47485.1 - 0.027 14.8 0.0 44 4.4 0.0 3.8 4 0 0 4 4 4 0 GRASP55/65 PDZ-like domain Multi_Drug_Res PF00893.19 EKX47486.1 - 3.4e-22 78.9 6.9 4.5e-22 78.5 6.9 1.1 1 0 0 1 1 1 1 Small Multidrug Resistance protein EamA PF00892.20 EKX47486.1 - 6.2e-05 23.2 13.2 7.9e-05 22.8 13.2 1.2 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 EKX47486.1 - 0.0068 16.4 0.7 0.0085 16.1 0.7 1.2 1 0 0 1 1 1 1 Putative transmembrane family 234 Clr5 PF14420.6 EKX47487.1 - 0.1 12.9 0.4 0.26 11.6 0.4 1.6 1 0 0 1 1 1 0 Clr5 domain API5 PF05918.11 EKX47489.1 - 2.2e-62 211.6 15.6 1.6e-57 195.6 3.8 2.0 1 1 1 2 2 2 2 Apoptosis inhibitory protein 5 (API5) RTP1_C1 PF10363.9 EKX47489.1 - 0.0031 17.7 0.1 0.0097 16.1 0.1 1.8 1 1 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 Se-cys_synth_N PF12390.8 EKX47490.1 - 0.0016 18.6 0.1 0.0035 17.5 0.1 1.5 1 0 0 1 1 1 1 Selenocysteine synthase N terminal WD40 PF00400.32 EKX47493.1 - 1.8e-43 145.7 19.2 1.5e-10 41.5 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX47493.1 - 1.2e-07 31.9 0.4 1.5 9.2 0.0 4.7 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EKX47493.1 - 0.014 15.5 0.1 29 4.8 0.0 3.9 2 1 2 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 EKX47493.1 - 0.062 11.9 1.4 8.1 5.0 0.1 3.7 2 2 2 4 4 4 0 Nucleoporin Nup120/160 TTL PF03133.15 EKX47495.1 - 1.2e-68 231.5 0.3 1.3e-68 231.3 0.3 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EKX47495.1 - 1e-09 38.0 0.2 4.2e-07 29.5 0.0 2.4 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EKX47495.1 - 0.018 14.3 0.0 0.093 12.0 0.0 1.9 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Gtr1_RagA PF04670.12 EKX47497.1 - 5.7e-97 323.6 0.5 7.1e-97 323.3 0.5 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EKX47497.1 - 2.1e-09 37.6 0.0 5.5e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EKX47497.1 - 9.2e-09 35.1 0.1 2e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EKX47497.1 - 1.8e-08 34.5 0.0 3.3e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 EKX47497.1 - 3e-07 30.0 0.1 6.6e-07 28.9 0.1 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family PduV-EutP PF10662.9 EKX47497.1 - 0.038 13.7 0.1 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Porphobil_deam PF01379.20 EKX47498.1 - 2e-73 246.3 0.0 2.7e-73 245.9 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EKX47498.1 - 2e-17 63.3 0.0 3.9e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain EFhand_Ca_insen PF08726.10 EKX47498.1 - 0.098 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Ca2+ insensitive EF hand GrpE PF01025.19 EKX47499.1 - 3.1e-42 144.1 6.9 7e-42 142.9 6.9 1.6 1 1 0 1 1 1 1 GrpE TMF_DNA_bd PF12329.8 EKX47499.1 - 0.00058 19.8 1.9 0.00058 19.8 1.9 2.8 3 0 0 3 3 3 1 TATA element modulatory factor 1 DNA binding NAPRTase_N PF17767.1 EKX47499.1 - 0.015 15.7 0.4 0.074 13.4 0.1 2.0 1 1 1 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Dsh_C PF12316.8 EKX47499.1 - 0.028 14.8 0.6 0.038 14.4 0.6 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal ATG16 PF08614.11 EKX47499.1 - 0.04 14.1 9.5 0.052 13.8 9.5 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF3694 PF12473.8 EKX47499.1 - 0.075 13.7 0.5 0.11 13.1 0.5 1.3 1 0 0 1 1 1 0 Kinesin protein Macoilin PF09726.9 EKX47499.1 - 0.22 10.0 9.0 0.26 9.8 9.0 1.0 1 0 0 1 1 1 0 Macoilin family DUF4407 PF14362.6 EKX47499.1 - 2 7.7 6.7 2.3 7.5 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CRA PF06589.11 EKX47499.1 - 2.1 8.4 8.8 3.9 7.6 8.8 1.4 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) DUF2681 PF10883.8 EKX47499.1 - 3 8.3 6.7 4.7 7.7 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) UPF0242 PF06785.11 EKX47499.1 - 3.4 7.7 9.1 4.9 7.2 9.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Presenilin PF01080.17 EKX47499.1 - 5.2 5.7 4.9 6.2 5.5 4.9 1.1 1 0 0 1 1 1 0 Presenilin Ribosomal_S3Ae PF01015.18 EKX47500.1 - 2.5e-86 288.4 9.8 3e-86 288.2 9.8 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 EKX47500.1 - 0.016 15.7 2.7 3.1 8.4 0.2 3.1 3 0 0 3 3 3 0 Translation initiation factor SUI1 Abhydro_lipase PF04083.16 EKX47500.1 - 0.11 12.0 0.0 0.24 11.0 0.0 1.6 1 1 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Ribosomal_S3Ae PF01015.18 EKX47501.1 - 2.5e-86 288.4 9.8 3e-86 288.2 9.8 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 EKX47501.1 - 0.016 15.7 2.7 3.1 8.4 0.2 3.1 3 0 0 3 3 3 0 Translation initiation factor SUI1 Abhydro_lipase PF04083.16 EKX47501.1 - 0.11 12.0 0.0 0.24 11.0 0.0 1.6 1 1 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region PDZ_6 PF17820.1 EKX47503.1 - 3.5e-07 30.0 0.3 7.9e-07 28.8 0.3 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX47503.1 - 5.4e-07 29.9 0.2 1.3e-06 28.7 0.2 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX47503.1 - 9.5e-06 25.9 0.1 2e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 PDZ domain ArAE_1_C PF11728.8 EKX47503.1 - 0.16 11.9 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain TAF6_C PF07571.13 EKX47505.1 - 1.6e-31 108.5 0.0 3.2e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 EKX47505.1 - 4.2e-19 68.5 0.3 1.7e-18 66.5 0.4 2.0 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 EKX47505.1 - 0.00031 21.1 0.2 0.00056 20.3 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EKX47505.1 - 0.074 13.1 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Aldo_ket_red PF00248.21 EKX47506.1 - 2.6e-75 253.4 0.0 3.2e-75 253.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Nipped-B_C PF12830.7 EKX47507.1 - 3.2e-11 43.5 0.6 1.6e-10 41.2 0.0 2.6 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus HEAT PF02985.22 EKX47507.1 - 1.1e-06 28.4 10.5 0.75 10.2 0.0 7.0 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 EKX47507.1 - 0.00022 21.6 2.6 1.9 9.0 0.1 5.1 3 1 1 4 4 4 2 HEAT repeats TMEM223 PF14640.6 EKX47507.1 - 0.054 13.7 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Transmembrane protein 223 TRM13 PF05206.14 EKX47507.1 - 0.21 11.1 4.2 4.6 6.7 0.1 3.6 3 0 0 3 3 3 0 Methyltransferase TRM13 C2 PF00168.30 EKX47510.1 - 7.1e-21 74.4 0.0 1.1e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 C2 domain YbbR PF07949.12 EKX47510.1 - 0.088 13.2 0.1 0.19 12.1 0.1 1.5 1 0 0 1 1 1 0 YbbR-like protein PKD_channel PF08016.12 EKX47511.1 - 2.7e-20 72.5 23.2 1.1e-16 60.6 13.0 2.3 2 0 0 2 2 2 2 Polycystin cation channel Ion_trans PF00520.31 EKX47511.1 - 6.3e-09 35.4 30.2 2.6e-08 33.4 27.6 2.9 2 1 0 2 2 2 1 Ion transport protein ATP19 PF11022.8 EKX47511.1 - 0.11 12.9 0.5 0.31 11.4 0.5 1.9 1 0 0 1 1 1 0 ATP synthase subunit K RNA_pol_3_Rpc31 PF11705.8 EKX47512.1 - 0.012 15.9 18.1 0.019 15.2 18.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 EKX47512.1 - 0.66 9.2 12.7 0.93 8.8 12.7 1.1 1 0 0 1 1 1 0 BUD22 EMP24_GP25L PF01105.24 EKX47513.1 - 6.6e-33 114.2 0.2 9.7e-33 113.6 0.2 1.2 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Carb_anhydrase PF00194.21 EKX47514.1 - 7.8e-23 81.3 1.8 1e-21 77.6 1.8 2.0 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF1035 PF06281.12 EKX47514.1 - 0.007 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1035) TGT PF01702.18 EKX47516.1 - 1.9e-74 250.9 0.0 2.4e-73 247.3 0.0 1.9 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase HTH_23 PF13384.6 EKX47517.1 - 0.064 13.1 0.4 0.16 11.8 0.2 1.8 2 0 0 2 2 2 0 Homeodomain-like domain DUF4817 PF16087.5 EKX47517.1 - 0.074 12.9 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) DndE PF08870.11 EKX47517.1 - 0.093 13.0 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 DNA sulphur modification protein DndE HTH_23 PF13384.6 EKX47518.1 - 0.057 13.2 0.4 0.14 12.0 0.2 1.8 2 0 0 2 2 2 0 Homeodomain-like domain DUF4817 PF16087.5 EKX47518.1 - 0.091 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) DndE PF08870.11 EKX47518.1 - 0.12 12.6 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 DNA sulphur modification protein DndE LysM PF01476.20 EKX47519.1 - 4.8e-17 61.7 0.0 4.1e-08 33.1 0.0 2.5 2 0 0 2 2 2 2 LysM domain Pro_isomerase PF00160.21 EKX47520.1 - 0.0079 16.5 0.0 3.7 7.8 0.0 2.2 1 1 1 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Phenol_Hydrox PF02332.18 EKX47521.1 - 0.022 14.3 0.4 0.025 14.1 0.4 1.1 1 0 0 1 1 1 0 Methane/Phenol/Toluene Hydroxylase DUF2001 PF09393.10 EKX47521.1 - 0.024 14.6 0.1 0.028 14.4 0.1 1.3 1 0 0 1 1 1 0 Phage tail tube protein Microtub_bind PF13931.6 EKX47522.1 - 0.38 11.1 1.3 9 6.7 0.1 2.3 2 1 0 2 2 2 0 Kinesin-associated microtubule-binding Med20 PF08612.11 EKX47523.1 - 2.9e-14 53.0 0.0 8.4e-14 51.5 0.0 1.8 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Sporozoite_P67 PF05642.11 EKX47523.1 - 0.32 9.0 8.3 0.43 8.6 8.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Med3 PF11593.8 EKX47523.1 - 0.72 9.0 9.5 1.1 8.4 9.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3439 PF11921.8 EKX47523.1 - 0.91 9.5 6.2 1.9 8.5 6.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) HNOBA PF07701.14 EKX47524.1 - 0.042 13.3 0.0 0.053 12.9 0.0 1.1 1 0 0 1 1 1 0 Heme NO binding associated SBP_bac_3 PF00497.20 EKX47525.1 - 3.5e-09 36.4 0.0 4.6e-05 23.0 0.0 2.1 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 EKX47525.1 - 0.00095 19.3 0.0 0.0022 18.2 0.0 1.6 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 EKX47525.1 - 0.0021 17.9 1.7 0.0021 17.9 1.7 1.8 1 1 1 2 2 2 1 Ligand-gated ion channel Ion_trans_2 PF07885.16 EKX47525.1 - 0.13 12.3 4.2 0.31 11.0 4.1 1.8 1 1 0 1 1 1 0 Ion channel DUF3965 PF13112.6 EKX47525.1 - 0.15 11.2 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3965) Arm PF00514.23 EKX47526.1 - 0.0017 18.3 9.0 2.8 8.1 0.1 5.8 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat Dynein_AAA_lid PF17852.1 EKX47526.1 - 0.042 13.9 2.3 0.12 12.5 0.5 2.5 2 1 0 2 2 2 0 Dynein heavy chain AAA lid domain Nt_Gln_amidase PF09764.9 EKX47527.1 - 5.2e-55 185.9 0.0 5.7e-55 185.8 0.0 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase Gln_deamidase_2 PF18626.1 EKX47527.1 - 0.054 13.8 0.1 0.077 13.3 0.1 1.3 1 0 0 1 1 1 0 Glutaminase Na_Pi_cotrans PF02690.15 EKX47528.1 - 9.6e-46 155.3 14.2 4.7e-28 98.0 3.9 2.3 2 0 0 2 2 2 2 Na+/Pi-cotransporter Iron_permease PF04120.12 EKX47528.1 - 7.5 6.3 5.2 7.9 6.3 0.1 2.3 2 0 0 2 2 2 0 Low affinity iron permease Glyco_transf_41 PF13844.6 EKX47531.1 - 4.9e-63 213.2 0.0 1.4e-34 119.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_2 PF07719.17 EKX47531.1 - 2.1e-22 77.4 10.5 7.4e-05 22.6 0.2 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 EKX47531.1 - 9.6e-20 69.5 9.5 5.8e-06 25.9 0.4 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 EKX47531.1 - 6.7e-18 63.7 12.1 0.0015 18.8 0.0 7.5 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 EKX47531.1 - 7.8e-16 58.4 8.6 1.5e-06 28.6 1.4 4.6 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 EKX47531.1 - 1.6e-15 56.0 6.3 0.0012 18.9 0.1 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 EKX47531.1 - 7.3e-13 48.0 22.5 1.6e-05 24.5 2.1 5.9 4 2 3 7 7 7 4 TPR repeat TPR_7 PF13176.6 EKX47531.1 - 1.3e-12 46.8 0.6 0.025 14.6 0.0 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX47531.1 - 1.8e-12 47.7 7.6 5.6e-05 23.7 3.2 4.7 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX47531.1 - 1.3e-11 44.6 13.5 0.0001 22.5 0.3 5.3 2 1 2 5 5 5 4 Tetratricopeptide repeat TPR_6 PF13174.6 EKX47531.1 - 1.2e-10 41.3 4.6 0.96 10.2 0.2 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX47531.1 - 2e-08 34.3 6.5 0.0016 18.6 0.1 3.7 3 1 2 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EKX47531.1 - 1.8e-07 31.4 7.6 0.38 11.7 0.3 6.5 3 1 4 7 7 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX47531.1 - 2e-05 24.3 11.0 0.59 10.1 0.1 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX47531.1 - 6.7e-05 23.0 3.1 0.034 14.3 0.0 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 EKX47531.1 - 0.00015 21.1 0.9 0.19 10.9 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_4 PF07721.14 EKX47531.1 - 0.00026 21.3 1.2 2.5 9.0 0.5 4.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 EKX47531.1 - 0.00026 20.8 5.3 0.22 11.2 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat-like domain SNAP PF14938.6 EKX47531.1 - 0.00066 19.2 7.3 0.025 14.0 2.4 2.4 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP Coatomer_E PF04733.14 EKX47531.1 - 0.032 13.6 1.1 0.13 11.6 0.2 2.1 1 1 0 2 2 2 0 Coatomer epsilon subunit DUF627 PF04781.12 EKX47531.1 - 0.11 12.5 1.6 29 4.7 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF627) PPR PF01535.20 EKX47531.1 - 0.14 12.5 1.5 31 5.1 0.1 4.3 5 0 0 5 5 5 0 PPR repeat TPR_20 PF14561.6 EKX47531.1 - 2.2 8.6 6.5 7 7.1 0.1 3.8 1 1 3 4 4 4 0 Tetratricopeptide repeat FAD_binding_7 PF03441.14 EKX47532.1 - 2.1e-53 180.8 2.3 2.1e-53 180.8 2.3 1.9 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EKX47532.1 - 2.3e-23 83.0 0.0 9.9e-23 80.9 0.0 2.1 1 1 0 1 1 1 1 DNA photolyase ABC1 PF03109.16 EKX47533.1 - 3.8e-28 98.0 0.0 7.9e-28 97.0 0.0 1.5 1 0 0 1 1 1 1 ABC1 family ING PF12998.7 EKX47534.1 - 0.0064 17.1 5.9 0.014 16.0 1.9 2.4 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding FAM184 PF15665.5 EKX47534.1 - 6.9 6.4 12.7 5.7 6.7 3.0 2.3 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B CRAL_TRIO PF00650.20 EKX47535.1 - 7.2e-23 81.1 0.0 1.4e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EKX47535.1 - 0.00028 21.0 0.0 0.0011 19.1 0.0 2.0 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain SAM_1 PF00536.30 EKX47536.1 - 3.9e-12 46.4 0.0 7.6e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EKX47536.1 - 2e-10 40.6 0.0 4.8e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HIP1_clath_bdg PF16515.5 EKX47536.1 - 0.00027 21.5 0.4 0.00075 20.1 0.4 1.7 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Apt1 PF10351.9 EKX47536.1 - 7.2 5.3 10.4 25 3.5 6.7 2.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain EF-hand_6 PF13405.6 EKX47537.1 - 0.0028 17.4 0.0 0.0074 16.1 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 EKX47537.1 - 0.014 15.9 0.0 0.082 13.4 0.0 2.3 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_1 PF00036.32 EKX47537.1 - 0.026 14.0 0.0 0.093 12.3 0.0 2.0 2 0 0 2 2 2 0 EF hand SPARC_Ca_bdg PF10591.9 EKX47537.1 - 0.14 12.5 0.0 0.24 11.7 0.0 1.6 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region ELO PF01151.18 EKX47538.1 - 1.2e-40 139.6 6.6 7.8e-29 100.9 3.0 2.0 1 1 1 2 2 2 2 GNS1/SUR4 family Meis_PKNOX_N PF16493.5 EKX47539.1 - 0.13 12.6 2.3 0.64 10.4 0.3 2.6 1 1 1 2 2 2 0 N-terminal of Homeobox Meis and PKNOX1 LRR_6 PF13516.6 EKX47542.1 - 1.2e-06 28.1 14.1 0.059 13.4 0.0 6.3 7 0 0 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.33 EKX47542.1 - 1.8 9.4 7.4 1.1e+02 4.0 0.0 5.4 5 1 0 5 5 5 0 Leucine Rich Repeat Aminotran_4 PF01063.19 EKX47543.1 - 1.6e-34 119.7 0.0 2e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Kelch_5 PF13854.6 EKX47544.1 - 6.7e-15 54.7 0.6 4.3e-05 23.4 0.0 4.3 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.25 EKX47544.1 - 3.5e-14 52.1 0.4 0.019 14.5 0.0 4.4 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 EKX47544.1 - 2.5e-11 43.4 4.1 0.017 15.4 0.3 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 EKX47544.1 - 4.8e-11 42.5 3.8 0.021 14.8 0.1 4.4 4 1 0 4 4 4 4 Galactose oxidase, central domain Kelch_2 PF07646.15 EKX47544.1 - 5.5e-08 32.5 3.9 2.6 8.2 0.0 4.3 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.6 EKX47544.1 - 1.4e-07 31.6 10.5 0.071 13.4 0.3 5.2 5 1 0 5 5 5 2 Galactose oxidase, central domain DUF4532 PF15046.6 EKX47544.1 - 0.083 12.0 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4532) MFS_1 PF07690.16 EKX47547.1 - 6.6e-39 133.8 51.1 1.8e-31 109.4 25.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EKX47547.1 - 3.3e-38 131.7 15.2 4.3e-38 131.3 15.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 EKX47547.1 - 3.4e-05 22.9 9.2 3.4e-05 22.9 9.2 2.7 1 1 1 3 3 3 1 MFS_1 like family MFS_4 PF06779.14 EKX47547.1 - 9.8e-05 21.8 7.0 9.8e-05 21.8 7.0 2.4 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB LRR_8 PF13855.6 EKX47548.1 - 2.3e-18 65.7 15.8 1.5e-09 37.4 5.6 4.2 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 EKX47548.1 - 1.8e-16 60.0 19.7 4.4e-05 23.8 5.5 5.1 3 2 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX47548.1 - 4e-08 32.7 15.5 1.8 9.5 0.2 7.3 7 1 1 8 8 8 4 Leucine Rich Repeat LRRNT_2 PF08263.12 EKX47548.1 - 0.014 15.7 3.8 0.033 14.5 3.8 1.6 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 EKX47548.1 - 0.24 11.5 17.7 3.6 7.9 0.1 6.2 7 0 0 7 7 7 0 Leucine Rich repeat UQ_con PF00179.26 EKX47549.1 - 2e-13 50.2 0.0 2.1e-13 50.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF563 PF04577.14 EKX47551.1 - 3.3e-17 63.3 0.0 5.6e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF779 PF05610.11 EKX47551.1 - 0.11 12.8 0.0 7.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF779) MCM PF00493.23 EKX47552.1 - 4.1e-65 219.0 0.0 7.3e-65 218.2 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EKX47552.1 - 2.8e-25 88.6 1.2 6e-25 87.5 1.2 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EKX47552.1 - 1.8e-18 66.7 0.4 5e-18 65.3 0.4 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain AAA_5 PF07728.14 EKX47552.1 - 1.5e-08 34.7 0.0 7.5e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EKX47552.1 - 4.1e-08 32.8 0.1 6.4e-05 22.4 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 EKX47552.1 - 7.7e-05 23.2 0.1 0.00017 22.2 0.1 1.6 1 0 0 1 1 1 1 MCM N-terminal domain AAA_3 PF07726.11 EKX47552.1 - 0.0011 18.8 0.0 0.0034 17.3 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 EKX47552.1 - 0.0063 16.9 0.0 0.017 15.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX47552.1 - 0.0071 16.7 0.1 0.048 14.1 0.1 2.3 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EKX47552.1 - 0.012 15.4 0.0 0.034 13.9 0.0 1.8 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 EKX47552.1 - 0.013 15.2 0.0 3 7.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_22 PF13401.6 EKX47552.1 - 0.08 13.2 0.1 0.24 11.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain CENP-K PF11802.8 EKX47553.1 - 1e-08 35.1 10.0 6e-07 29.3 10.0 2.3 1 1 0 1 1 1 1 Centromere-associated protein K Semialdhyde_dh PF01118.24 EKX47553.1 - 0.14 12.6 0.2 0.35 11.3 0.0 1.8 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain AAA_13 PF13166.6 EKX47553.1 - 0.56 8.8 6.0 0.77 8.3 6.0 1.2 1 0 0 1 1 1 0 AAA domain FHA PF00498.26 EKX47554.1 - 1.2e-05 25.5 0.0 1.8e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 FHA domain DUF724 PF05266.14 EKX47555.1 - 0.012 15.4 0.5 0.016 15.1 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) MRFAP1 PF15155.6 EKX47555.1 - 0.013 16.1 0.1 0.017 15.6 0.1 1.3 1 1 0 1 1 1 0 MORF4 family-associated protein1 OST_P2 PF18235.1 EKX47555.1 - 0.025 14.5 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 Oligosaccharyltransferase Peripheral 2 domain DUF592 PF04574.13 EKX47555.1 - 0.076 12.8 0.1 0.078 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF592) FYVE_2 PF02318.16 EKX47555.1 - 1.4 9.2 5.1 0.37 11.0 1.9 1.6 2 0 0 2 2 2 0 FYVE-type zinc finger Kinesin PF00225.23 EKX47556.1 - 7e-94 314.5 0.4 8.1e-94 314.3 0.4 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX47556.1 - 5.2e-17 62.2 0.0 9.9e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding CaMKII_AD PF08332.10 EKX47556.1 - 0.034 14.3 0.0 0.069 13.3 0.0 1.5 1 0 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II association domain TPR_12 PF13424.6 EKX47557.1 - 2.3e-47 159.1 23.0 7.4e-12 45.4 0.1 7.6 3 2 6 9 9 9 6 Tetratricopeptide repeat TPR_10 PF13374.6 EKX47557.1 - 5e-28 96.2 19.5 5.4e-08 32.5 0.0 9.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.28 EKX47557.1 - 1.1e-23 82.1 10.7 0.00011 21.8 0.0 7.9 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 EKX47557.1 - 2.5e-20 70.9 8.5 0.00015 21.6 0.0 8.3 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 EKX47557.1 - 8.3e-17 59.9 13.2 0.0012 18.9 0.0 7.6 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 EKX47557.1 - 2.8e-14 52.0 13.0 0.0023 17.8 0.1 7.9 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX47557.1 - 1.6e-08 34.4 10.7 0.0034 16.8 0.0 4.0 2 1 2 4 4 4 4 MalT-like TPR region SNAP PF14938.6 EKX47557.1 - 6.4e-08 32.4 1.2 0.0066 15.9 0.0 3.3 2 1 0 3 3 3 2 Soluble NSF attachment protein, SNAP TPR_11 PF13414.6 EKX47557.1 - 1.1e-06 28.3 0.9 0.19 11.4 0.1 6.5 6 1 0 6 6 6 1 TPR repeat TPR_19 PF14559.6 EKX47557.1 - 1.4e-06 28.7 9.3 0.00019 21.9 0.0 5.1 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX47557.1 - 2.3e-06 28.0 6.2 0.029 15.2 0.0 7.0 6 3 2 8 8 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX47557.1 - 0.00067 20.2 4.1 1.3 9.7 0.0 4.8 3 1 2 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX47557.1 - 0.00091 19.7 11.0 0.056 14.1 0.0 6.4 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX47557.1 - 0.0041 17.4 7.2 0.043 14.2 0.1 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat MIT PF04212.18 EKX47557.1 - 0.007 16.4 8.2 2.5 8.2 0.0 5.3 5 1 1 6 6 6 1 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 EKX47557.1 - 0.0091 16.0 5.7 0.11 12.6 0.1 4.1 5 1 0 5 5 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 EKX47557.1 - 0.023 13.9 5.6 0.32 10.2 0.4 3.6 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_5 PF12688.7 EKX47557.1 - 0.045 14.0 2.3 1.7 8.9 0.0 3.4 3 1 0 3 3 3 0 Tetratrico peptide repeat RPN7 PF10602.9 EKX47557.1 - 0.07 12.8 7.3 3.5 7.3 0.2 3.8 3 1 0 3 3 3 0 26S proteasome subunit RPN7 TPR_3 PF07720.12 EKX47557.1 - 0.095 12.7 0.1 0.46 10.5 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PTS_IIA PF02255.16 EKX47557.1 - 0.1 12.6 0.8 38 4.4 0.0 3.5 3 1 0 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit TPR_4 PF07721.14 EKX47557.1 - 0.2 12.4 0.0 0.2 12.4 0.0 4.3 5 0 0 5 5 3 0 Tetratricopeptide repeat DHR10 PF18595.1 EKX47557.1 - 0.83 9.7 5.5 0.14 12.2 0.5 2.4 2 0 0 2 2 1 0 Designed helical repeat protein 10 domain DUF627 PF04781.12 EKX47557.1 - 1.5 8.9 7.9 14 5.7 0.4 4.6 3 1 1 4 4 4 0 Protein of unknown function (DUF627) DUF1720 PF08226.11 EKX47559.1 - 0.0016 18.8 1.9 0.27 11.7 1.9 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1720) DcpS_C PF11969.8 EKX47560.1 - 3.7e-19 69.3 0.1 6.3e-19 68.5 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EKX47560.1 - 0.035 14.8 0.1 0.1 13.4 0.0 1.8 2 0 0 2 2 2 0 HIT domain Zn_clus PF00172.18 EKX47561.1 - 6.9e-07 29.3 13.6 9.6e-07 28.8 13.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_17 PF13431.6 EKX47562.1 - 6.4e-06 26.2 0.3 0.0069 16.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX47562.1 - 1e-05 25.7 0.6 2.7e-05 24.4 0.6 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX47562.1 - 1.7e-05 25.2 0.1 0.008 16.7 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX47562.1 - 4.5e-05 23.9 0.5 0.065 14.1 0.2 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX47562.1 - 0.00026 20.7 0.1 0.13 12.1 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX47562.1 - 0.0013 18.7 0.4 0.091 12.9 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX47562.1 - 0.0016 18.1 0.1 0.0059 16.3 0.0 1.9 2 0 0 2 2 2 1 TPR repeat TPR_8 PF13181.6 EKX47562.1 - 0.015 15.5 0.0 0.099 12.9 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Cas_Csy4 PF09618.10 EKX47562.1 - 0.022 14.9 2.9 0.031 14.4 2.1 1.6 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy4) TPR_10 PF13374.6 EKX47562.1 - 0.032 14.1 0.6 0.67 9.9 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EKX47562.1 - 0.057 13.5 0.1 0.2 11.7 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat SLATT_5 PF18160.1 EKX47562.1 - 0.5 9.7 1.5 0.92 8.8 1.5 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF2431 PF10354.9 EKX47563.1 - 3.2e-35 121.9 0.0 7e-35 120.8 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) zf-met PF12874.7 EKX47563.1 - 4.8e-05 23.6 0.5 0.00011 22.5 0.5 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EKX47563.1 - 0.00018 21.7 1.3 0.00018 21.7 1.3 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EKX47563.1 - 0.00036 20.8 0.4 0.00055 20.2 0.4 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) DUF2671 PF10877.8 EKX47563.1 - 0.013 15.3 0.0 0.043 13.6 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2671) zf-C2H2_4 PF13894.6 EKX47563.1 - 0.027 15.3 0.1 0.079 13.8 0.1 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EKX47563.1 - 0.052 14.0 0.2 0.16 12.5 0.2 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type SPRY PF00622.28 EKX47564.1 - 0.0026 17.9 0.0 0.0035 17.4 0.0 1.3 1 0 0 1 1 1 1 SPRY domain TPR_8 PF13181.6 EKX47565.1 - 1.8e-22 77.6 3.9 0.0012 18.9 0.1 5.4 5 1 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 EKX47565.1 - 2.8e-21 73.8 1.7 0.0011 19.0 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 EKX47565.1 - 9.5e-21 72.7 1.8 9.4e-05 22.1 0.1 6.0 5 1 0 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.6 EKX47565.1 - 1.7e-14 53.9 1.0 1.1e-07 32.0 0.1 4.3 1 1 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX47565.1 - 1.8e-13 50.9 0.8 0.00093 19.8 0.6 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX47565.1 - 8.7e-13 47.9 4.4 0.021 15.6 0.0 4.5 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 EKX47565.1 - 5.4e-12 45.2 4.4 0.0029 17.2 0.0 5.3 3 2 3 6 6 6 4 TPR repeat TPR_17 PF13431.6 EKX47565.1 - 1.7e-11 43.6 0.7 0.005 17.1 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX47565.1 - 3.2e-11 43.1 4.6 0.034 14.8 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX47565.1 - 8.6e-10 38.2 9.2 0.00069 19.4 0.2 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX47565.1 - 5.3e-09 35.5 8.9 0.38 10.9 0.1 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EKX47565.1 - 8.6e-08 32.6 5.6 0.0013 19.2 0.1 3.2 1 1 3 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX47565.1 - 2.4e-06 27.7 6.0 0.021 15.0 0.2 2.5 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 EKX47565.1 - 0.00022 21.7 2.4 0.0022 18.4 0.2 2.2 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_15 PF13429.6 EKX47565.1 - 0.00033 19.9 4.7 0.016 14.4 0.2 3.1 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 EKX47565.1 - 0.00072 19.3 2.9 0.078 12.7 0.5 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat-like domain TPR_20 PF14561.6 EKX47565.1 - 0.0011 19.2 0.4 0.0031 17.8 0.2 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX47565.1 - 0.0017 18.4 1.0 0.0036 17.4 0.1 2.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX47565.1 - 0.034 13.5 3.0 2.7 7.3 1.5 2.7 1 1 1 2 2 2 0 MalT-like TPR region DUF4299 PF14132.6 EKX47565.1 - 0.051 13.0 0.2 0.1 12.0 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4299) DUF2524 PF10732.9 EKX47565.1 - 0.19 12.0 2.1 0.16 12.3 0.4 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF2524) DUF627 PF04781.12 EKX47565.1 - 0.36 10.9 2.5 12 6.0 0.1 2.5 2 1 1 3 3 2 0 Protein of unknown function (DUF627) HHH_8 PF14716.6 EKX47565.1 - 0.48 10.8 4.0 9.5 6.7 0.1 2.9 2 1 1 3 3 3 0 Helix-hairpin-helix domain MIT PF04212.18 EKX47565.1 - 3.2 7.9 7.2 7.7 6.7 0.0 3.4 4 1 0 4 4 3 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 EKX47565.1 - 3.4 8.6 5.4 1.4e+02 3.6 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Cys_Met_Meta_PP PF01053.20 EKX47568.1 - 3.2e-131 437.4 0.0 3.9e-131 437.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme CoA_binding_2 PF13380.6 EKX47568.1 - 2.1e-10 41.1 0.3 7.5e-08 32.9 0.1 2.7 3 0 0 3 3 3 1 CoA binding domain Beta_elim_lyase PF01212.21 EKX47568.1 - 1.4e-06 27.8 0.0 2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EKX47568.1 - 4.5e-06 26.1 0.0 6.5e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EKX47568.1 - 0.00077 18.9 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.16 EKX47568.1 - 0.0012 17.8 0.0 0.0016 17.3 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein Aminotran_5 PF00266.19 EKX47568.1 - 0.0091 15.0 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V SepSecS PF05889.13 EKX47568.1 - 0.17 10.6 0.0 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS TPT PF03151.16 EKX47570.1 - 1.4e-07 31.2 12.5 2.1e-07 30.6 12.5 1.3 1 1 0 1 1 1 1 Triose-phosphate Transporter family Ank_5 PF13857.6 EKX47572.1 - 1.2e-13 50.9 0.4 8.4e-09 35.5 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX47572.1 - 1.3e-12 47.9 0.1 8.7e-06 26.2 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX47572.1 - 1.5e-09 38.3 0.3 2.4e-09 37.7 0.3 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX47572.1 - 1.8e-08 34.0 0.4 0.006 17.0 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EKX47572.1 - 3.4e-07 30.4 7.7 3.6e-05 24.0 0.3 3.1 3 1 0 3 3 3 2 Ankyrin repeat TPR_19 PF14559.6 EKX47573.1 - 6.2e-12 45.9 16.4 8.2e-07 29.4 1.6 3.5 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX47573.1 - 1.5e-09 38.3 5.7 4.7e-08 33.5 0.9 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX47573.1 - 3.6e-09 36.8 11.0 0.00033 20.9 0.4 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX47573.1 - 9.8e-09 34.7 18.3 0.0018 18.2 0.0 5.4 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX47573.1 - 1.2e-07 31.9 8.3 0.0037 18.0 0.0 4.5 4 1 3 7 7 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX47573.1 - 2.7e-07 30.1 15.6 4.6e-06 26.2 0.1 4.3 4 1 1 5 5 5 2 TPR repeat TPR_1 PF00515.28 EKX47573.1 - 7.5e-06 25.5 23.0 0.001 18.8 0.0 5.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 EKX47573.1 - 7.4e-05 22.9 8.5 0.046 14.1 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX47573.1 - 0.00038 20.3 12.4 0.27 11.3 0.0 5.0 6 0 0 6 6 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX47573.1 - 0.00043 20.5 2.9 0.00043 20.5 2.9 2.3 2 0 0 2 2 1 1 Anaphase-promoting complex, cyclosome, subunit 3 Lipase_GDSL_2 PF13472.6 EKX47573.1 - 0.015 15.7 0.0 0.63 10.4 0.0 2.6 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family TPR_20 PF14561.6 EKX47573.1 - 0.039 14.3 6.0 0.078 13.3 0.0 2.8 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 EKX47573.1 - 0.078 13.1 4.0 4 7.6 0.0 3.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX47573.1 - 0.12 13.0 9.8 4.4 8.2 0.6 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 EKX47573.1 - 0.14 12.2 0.2 0.14 12.2 0.2 5.0 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 EKX47573.1 - 0.15 12.3 0.1 0.15 12.3 0.1 5.5 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX47573.1 - 6.1 6.9 13.9 21 5.1 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.9 EKX47573.1 - 6.5 6.4 9.8 0.37 10.5 0.6 3.3 3 1 0 3 3 3 0 26S proteasome subunit RPN7 Zn_clus PF00172.18 EKX47576.1 - 9.7e-17 60.8 39.7 3.6e-07 30.2 14.0 3.2 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 EKX47578.1 - 1.1e-17 63.8 38.9 1.1e-07 31.8 12.4 3.2 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_12 PF13424.6 EKX47579.1 - 2e-12 47.2 9.5 7.6e-06 26.1 0.7 6.5 5 1 5 10 10 10 4 Tetratricopeptide repeat NACHT PF05729.12 EKX47579.1 - 4.6e-11 42.9 0.2 2.7e-10 40.4 0.0 2.4 3 0 0 3 3 3 1 NACHT domain TPR_10 PF13374.6 EKX47579.1 - 4.8e-08 32.6 6.0 0.28 11.1 0.1 7.9 8 0 0 8 8 8 1 Tetratricopeptide repeat DUF4062 PF13271.6 EKX47579.1 - 1.5e-05 25.2 0.0 6.7e-05 23.2 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) AAA_16 PF13191.6 EKX47579.1 - 6e-05 23.5 0.1 0.0033 17.8 0.0 3.4 4 0 0 4 4 4 1 AAA ATPase domain TPR_MalT PF17874.1 EKX47579.1 - 0.00035 20.0 5.6 0.41 10.0 3.2 3.0 2 1 0 2 2 2 2 MalT-like TPR region ATPase_2 PF01637.18 EKX47579.1 - 0.016 15.1 0.1 0.094 12.6 0.0 2.3 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea EF-hand_1 PF00036.32 EKX47579.1 - 0.018 14.5 2.3 0.029 13.9 0.6 2.3 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.6 EKX47579.1 - 0.091 12.3 0.4 0.29 10.7 0.4 1.9 1 0 0 1 1 1 0 EF hand TPR_4 PF07721.14 EKX47579.1 - 0.25 12.1 11.1 12 6.9 0.5 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 EKX47579.1 - 0.81 10.4 4.2 12 6.6 0.1 3.9 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EKX47579.1 - 4.9 7.5 7.4 22 5.5 0.1 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Ammonium_transp PF00909.21 EKX47580.1 - 3.9e-80 269.5 30.5 4.9e-80 269.2 30.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Mito_fiss_reg PF05308.11 EKX47581.1 - 2.3 8.2 6.2 3.7 7.5 6.2 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Ctf8 PF09696.10 EKX47582.1 - 5.5e-14 52.7 0.5 1.5e-12 48.1 0.5 2.4 1 1 0 1 1 1 1 Ctf8 MRF_C1 PF13887.6 EKX47584.1 - 0.051 12.7 0.4 0.22 10.7 0.1 2.1 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 Pro_isomerase PF00160.21 EKX47585.1 - 2.8e-52 177.2 0.1 4.9e-52 176.4 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 EKX47585.1 - 4.3e-15 55.9 1.8 0.0091 16.8 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX47585.1 - 0.0003 21.0 0.6 0.94 9.8 0.0 4.3 2 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EKX47585.1 - 0.056 12.1 0.0 0.081 11.6 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DMA PF03474.14 EKX47585.1 - 4.4 7.0 6.2 6.2 6.5 0.1 3.5 4 0 0 4 4 4 0 DMRTA motif Methyltransf_25 PF13649.6 EKX47586.1 - 2.4e-15 57.0 0.0 5.9e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX47586.1 - 7.1e-14 51.9 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX47586.1 - 2.1e-12 47.5 0.0 5.8e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EKX47586.1 - 7.7e-11 41.9 0.0 1.3e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 EKX47586.1 - 2.7e-07 30.6 0.0 5.7e-07 29.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EKX47586.1 - 5e-07 29.4 0.0 8.4e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 EKX47586.1 - 9.8e-06 25.6 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EKX47586.1 - 3.2e-05 23.4 0.0 6.6e-05 22.4 0.0 1.5 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.12 EKX47586.1 - 0.00018 22.2 0.0 0.0004 21.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EKX47586.1 - 0.00021 20.3 0.0 0.0003 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 EKX47586.1 - 0.00046 19.6 0.0 0.00074 18.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EKX47586.1 - 0.00087 18.7 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EKX47586.1 - 0.0017 18.4 0.0 0.0036 17.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 EKX47586.1 - 0.003 18.6 0.0 0.0064 17.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EKX47586.1 - 0.0073 15.6 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase domain PCMT PF01135.19 EKX47586.1 - 0.012 15.4 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 EKX47586.1 - 0.012 15.3 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Cons_hypoth95 PF03602.15 EKX47586.1 - 0.014 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 FtsJ PF01728.19 EKX47586.1 - 0.023 14.8 0.0 0.067 13.3 0.0 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase PRMT5 PF05185.16 EKX47586.1 - 0.067 13.0 0.1 0.14 12.0 0.1 1.6 1 1 0 1 1 1 0 PRMT5 arginine-N-methyltransferase EF-hand_8 PF13833.6 EKX47587.1 - 9e-11 41.5 1.4 3.8e-08 33.0 0.1 2.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.6 EKX47587.1 - 7.5e-10 39.1 4.0 5.7e-08 33.1 0.4 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX47587.1 - 7.8e-10 37.9 0.1 0.0025 17.6 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EKX47587.1 - 3.9e-08 32.3 4.1 0.0049 16.3 0.0 4.2 3 1 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 EKX47587.1 - 0.00019 20.8 4.3 0.0043 16.5 0.0 3.6 3 1 0 3 3 3 1 EF hand SHOCT PF09851.9 EKX47587.1 - 0.02 14.6 3.2 0.02 14.6 3.2 2.6 2 0 0 2 2 2 0 Short C-terminal domain DMAP_binding PF06464.11 EKX47587.1 - 0.099 13.5 0.8 0.17 12.7 0.8 1.4 1 0 0 1 1 1 0 DMAP1-binding Domain AAA_11 PF13086.6 EKX47588.1 - 1e-64 218.9 0.4 1e-64 218.9 0.4 3.0 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.6 EKX47588.1 - 3.9e-61 206.1 0.0 9.9e-61 204.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EKX47588.1 - 6.6e-11 42.4 5.6 0.0025 17.6 0.0 4.6 5 0 0 5 5 4 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 EKX47588.1 - 3.5e-09 37.1 0.1 0.0027 18.1 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.6 EKX47588.1 - 2.2e-08 34.0 0.1 0.0039 16.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain zf-trcl PF13451.6 EKX47588.1 - 1.7e-07 31.0 0.3 4.1e-07 29.8 0.3 1.7 1 0 0 1 1 1 1 Probable zinc-ribbon domain UvrD_C PF13361.6 EKX47588.1 - 2.6e-05 23.8 1.3 0.027 13.8 0.0 3.4 3 1 1 4 4 4 2 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 EKX47588.1 - 0.00017 21.4 0.0 0.00039 20.2 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 EKX47588.1 - 0.00063 20.0 0.6 0.016 15.5 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 EKX47588.1 - 0.00071 20.0 0.1 0.0044 17.4 0.0 2.4 2 0 0 2 2 1 1 AAA ATPase domain AAA PF00004.29 EKX47588.1 - 0.0068 16.8 2.4 0.0096 16.3 0.0 2.6 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 EKX47588.1 - 0.011 15.7 0.8 1.4 8.9 0.0 3.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_5 PF07728.14 EKX47588.1 - 0.013 15.4 0.1 0.11 12.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EKX47588.1 - 0.016 15.1 0.1 0.057 13.3 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain UvrD-helicase PF00580.21 EKX47588.1 - 0.016 14.7 2.4 1.4 8.4 0.0 3.7 4 1 0 4 4 4 0 UvrD/REP helicase N-terminal domain NB-ARC PF00931.22 EKX47588.1 - 0.024 13.8 0.0 0.25 10.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 EKX47588.1 - 0.025 15.1 3.8 3.1 8.3 0.0 4.1 4 0 0 4 4 4 0 AAA domain NTPase_1 PF03266.15 EKX47588.1 - 0.056 13.4 1.2 0.83 9.6 0.1 2.9 2 0 0 2 2 2 0 NTPase AAA_29 PF13555.6 EKX47588.1 - 0.06 13.1 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2075 PF09848.9 EKX47588.1 - 0.063 12.5 3.1 0.31 10.2 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 EKX47588.1 - 0.066 12.8 0.2 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 EKX47588.1 - 0.067 12.9 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EKX47588.1 - 0.088 12.2 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EKX47588.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 EKX47588.1 - 1.5 9.3 6.0 6.4 7.2 0.0 3.5 4 0 0 4 4 3 0 AAA domain TraG_N PF07916.11 EKX47589.1 - 0.0059 15.5 0.7 0.0059 15.5 0.7 1.3 1 1 0 1 1 1 1 TraG-like protein, N-terminal region DUF2207 PF09972.9 EKX47589.1 - 0.019 13.7 0.2 0.027 13.2 0.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FA_desaturase PF00487.24 EKX47589.1 - 1.3 8.8 4.6 1.6 8.5 4.6 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Peptidase_S24 PF00717.23 EKX47590.1 - 1.1e-09 38.1 0.1 1.7e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like Kinesin PF00225.23 EKX47591.1 - 8e-67 225.5 1.7 1.1e-66 225.1 0.2 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EKX47591.1 - 3.9e-15 56.1 0.1 8.2e-15 55.0 0.1 1.6 1 0 0 1 1 1 1 Microtubule binding ResIII PF04851.15 EKX47591.1 - 0.01 15.8 0.5 0.024 14.6 0.5 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 EKX47591.1 - 0.012 16.0 0.0 0.035 14.5 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 EKX47591.1 - 0.021 14.9 1.3 0.11 12.5 0.5 2.5 2 1 1 3 3 3 0 Helicase HerA, central domain T2SSE PF00437.20 EKX47591.1 - 0.038 13.1 0.1 0.079 12.0 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Defensin_3 PF08131.11 EKX47591.1 - 0.063 13.5 1.3 0.15 12.3 1.3 1.6 1 0 0 1 1 1 0 Defensin-like peptide family Sigma54_activat PF00158.26 EKX47591.1 - 0.077 12.7 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain PIF1 PF05970.14 EKX47591.1 - 0.079 12.1 0.2 0.079 12.1 0.2 1.5 2 0 0 2 2 2 0 PIF1-like helicase Bac_DnaA PF00308.18 EKX47591.1 - 0.084 12.7 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein TsaE PF02367.17 EKX47591.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 EKX47591.1 - 0.12 12.8 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Agouti PF05039.12 EKX47591.1 - 0.62 10.8 6.0 0.91 10.3 3.4 2.7 2 0 0 2 2 2 0 Agouti protein DUF393 PF04134.12 EKX47592.1 - 1.5e-27 97.2 0.0 1.8e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF393 Ank_2 PF12796.7 EKX47593.1 - 8.1e-21 74.4 2.3 1.3e-11 44.9 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX47593.1 - 1.5e-16 58.7 0.4 0.00028 21.1 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 EKX47593.1 - 1.9e-16 60.2 4.4 4.3e-05 24.0 0.3 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EKX47593.1 - 2.7e-16 59.2 4.0 0.00018 21.8 0.1 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EKX47593.1 - 5.9e-12 45.6 1.7 8.2e-08 32.4 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) His_Phos_1 PF00300.22 EKX47594.1 - 1.2e-07 31.6 0.0 0.0018 18.0 0.0 3.7 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) RNA_pol_I_TF PF04090.12 EKX47594.1 - 0.065 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific initiation factor aGPT-Pplase3 PF18746.1 EKX47597.1 - 0.11 11.9 0.8 0.15 11.3 0.8 1.1 1 0 0 1 1 1 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 3 Ion_trans PF00520.31 EKX47601.1 - 6.3e-183 605.2 75.6 4.3e-57 193.2 10.4 4.1 4 0 0 4 4 4 4 Ion transport protein EF-hand_1 PF00036.32 EKX47601.1 - 1.7e-11 42.8 2.2 9.9e-05 21.6 0.5 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX47601.1 - 1.4e-10 40.2 1.4 2.3e-05 24.0 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EKX47601.1 - 4.6e-09 36.6 6.0 2.1e-07 31.3 1.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX47601.1 - 3.5e-06 26.3 0.3 0.034 13.6 0.4 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX47601.1 - 5e-05 23.1 1.0 0.0015 18.3 0.1 2.7 1 1 1 2 2 2 2 EF-hand domain pair DUF938 PF06080.12 EKX47601.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PKD_channel PF08016.12 EKX47601.1 - 0.96 8.1 61.7 0.56 8.8 0.5 10.4 8 2 2 10 10 10 0 Polycystin cation channel HA PF03457.14 EKX47602.1 - 1.7e-05 25.0 3.8 0.0004 20.6 0.2 3.0 3 0 0 3 3 3 2 Helicase associated domain IQ PF00612.27 EKX47604.1 - 0.00089 18.8 4.0 0.038 13.8 0.2 3.4 3 0 0 3 3 3 2 IQ calmodulin-binding motif DUF4606 PF15379.6 EKX47604.1 - 0.047 13.9 0.4 0.64 10.3 0.4 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4606) DAGAT PF03982.13 EKX47605.1 - 2.6e-48 164.5 0.0 3.2e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 EKX47605.1 - 0.0024 17.5 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase PapD-like PF14874.6 EKX47606.1 - 0.0062 16.7 0.1 0.014 15.5 0.1 1.6 1 0 0 1 1 1 1 Flagellar-associated PapD-like TIR_2 PF13676.6 EKX47607.1 - 0.026 15.1 0.0 0.33 11.6 0.0 2.8 2 0 0 2 2 2 0 TIR domain PP2C PF00481.21 EKX47608.1 - 0.025 14.2 0.0 0.028 14.0 0.0 1.0 1 0 0 1 1 1 0 Protein phosphatase 2C PALP PF00291.25 EKX47609.1 - 3.1e-56 190.9 2.8 2.2e-55 188.2 2.8 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ACT PF01842.25 EKX47609.1 - 0.032 14.0 0.0 0.098 12.5 0.0 1.8 1 0 0 1 1 1 0 ACT domain ACT_6 PF13740.6 EKX47609.1 - 0.066 13.2 0.0 0.18 11.8 0.0 1.7 1 1 0 1 1 1 0 ACT domain Peptidase_C48 PF02902.19 EKX47613.1 - 5.2e-10 39.5 0.0 5.8e-10 39.4 0.0 1.0 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Methyltransf_11 PF08241.12 EKX47614.1 - 2.8e-13 50.3 0.1 7.5e-13 48.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX47614.1 - 4.6e-08 33.7 0.0 9.4e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EKX47614.1 - 6.1e-08 32.5 0.0 8.9e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.6 EKX47614.1 - 1.1e-06 28.5 0.0 1.8e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX47614.1 - 1e-05 26.2 0.0 1.5e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX47614.1 - 0.00017 21.0 0.0 0.00025 20.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EKX47614.1 - 0.00038 20.3 0.0 0.00049 20.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 EKX47614.1 - 0.0014 17.3 0.0 0.0019 16.8 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.15 EKX47614.1 - 0.0089 15.9 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase N6_N4_Mtase PF01555.18 EKX47614.1 - 0.089 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 DNA methylase THEG PF14912.6 EKX47615.1 - 3.1 8.3 8.3 11 6.5 0.2 3.7 3 0 0 3 3 3 0 Testicular haploid expressed repeat HU-CCDC81_bac_2 PF18175.1 EKX47615.1 - 9.9 6.1 5.8 13 5.8 0.0 3.5 4 1 0 4 4 4 0 CCDC81-like prokaryotic HU domain 2 AAA_6 PF12774.7 EKX47616.1 - 5.1e-156 518.7 0.2 3.3e-153 509.4 0.0 4.0 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EKX47616.1 - 5.8e-129 430.7 7.1 5.8e-129 430.7 7.1 3.5 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 EKX47616.1 - 3.3e-105 351.7 0.0 5.7e-104 347.6 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 EKX47616.1 - 4.9e-105 350.5 0.0 8.2e-104 346.5 0.0 2.8 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EKX47616.1 - 1.2e-86 289.4 0.6 1.2e-86 289.4 0.6 2.2 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 EKX47616.1 - 1.6e-67 226.6 0.0 9e-62 207.8 0.0 4.3 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EKX47616.1 - 3.5e-53 179.8 0.1 1.1e-52 178.2 0.0 2.0 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 EKX47616.1 - 2.2e-44 151.9 13.8 4.7e-44 150.8 13.8 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EKX47616.1 - 1.9e-42 144.1 0.0 1e-41 141.8 0.0 2.4 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EKX47616.1 - 5.8e-29 100.8 0.0 3.2e-28 98.4 0.0 2.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EKX47616.1 - 3.3e-21 75.4 1.7 5.3e-21 74.7 0.1 2.3 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 EKX47616.1 - 2.4e-17 63.2 0.0 1.8e-05 24.7 0.0 6.0 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA PF00004.29 EKX47616.1 - 2.5e-08 34.4 0.0 0.1 13.0 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EKX47616.1 - 7.9e-07 29.7 0.3 0.12 13.0 0.0 4.1 4 0 0 4 4 3 2 AAA domain AAA_22 PF13401.6 EKX47616.1 - 3.6e-06 27.3 0.0 0.27 11.5 0.0 5.3 5 0 0 5 5 4 1 AAA domain AAA_29 PF13555.6 EKX47616.1 - 1.5e-05 24.7 2.0 0.018 14.8 0.1 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EKX47616.1 - 2.3e-05 24.9 9.5 3.9 7.8 0.0 5.9 6 0 0 6 6 5 2 AAA ATPase domain RNA_helicase PF00910.22 EKX47616.1 - 7.2e-05 23.1 0.3 2.1 8.8 0.0 4.5 4 0 0 4 4 4 1 RNA helicase ABC_tran PF00005.27 EKX47616.1 - 0.0041 17.6 0.2 3.3 8.2 0.0 3.9 3 0 0 3 3 3 1 ABC transporter AAA_25 PF13481.6 EKX47616.1 - 0.0044 16.6 1.6 1.1 8.8 0.0 3.7 4 0 0 4 4 3 1 AAA domain RsgA_GTPase PF03193.16 EKX47616.1 - 0.0083 16.0 3.1 1.8 8.4 0.0 4.0 4 0 0 4 4 3 1 RsgA GTPase UPF0240 PF06784.11 EKX47616.1 - 0.013 15.5 0.0 0.061 13.4 0.0 2.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) TsaE PF02367.17 EKX47616.1 - 0.017 15.1 0.9 1.2 9.1 0.0 3.5 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EKX47616.1 - 0.02 14.7 0.5 1.1 8.9 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_30 PF13604.6 EKX47616.1 - 0.027 14.2 5.0 4 7.1 0.2 3.7 4 0 0 4 4 4 0 AAA domain NACHT PF05729.12 EKX47616.1 - 0.035 14.0 0.5 1.3 9.0 0.0 3.5 4 0 0 4 4 3 0 NACHT domain AAA_28 PF13521.6 EKX47616.1 - 0.044 14.0 4.6 0.42 10.8 0.1 3.2 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.6 EKX47616.1 - 0.047 13.9 4.5 0.79 9.9 0.1 3.9 4 0 0 4 4 4 0 AAA domain Cytidylate_kin PF02224.18 EKX47616.1 - 0.13 12.0 0.6 20 4.8 0.1 3.0 2 0 0 2 2 2 0 Cytidylate kinase CbiA PF01656.23 EKX47616.1 - 0.54 10.3 3.1 83 3.3 0.1 4.4 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain T2SSE PF00437.20 EKX47616.1 - 0.67 9.0 5.7 1.1 8.2 0.0 3.7 5 0 0 5 5 5 0 Type II/IV secretion system protein PriC PF07445.12 EKX47616.1 - 0.67 9.9 9.0 0.22 11.5 1.2 2.8 2 0 0 2 2 2 0 Primosomal replication protein priC Fzo_mitofusin PF04799.13 EKX47616.1 - 1 8.9 5.3 0.8 9.2 1.1 3.0 2 0 0 2 2 2 0 fzo-like conserved region DUF4600 PF15372.6 EKX47616.1 - 9.1 6.7 8.6 2.4 8.6 1.7 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) MIF4G PF02854.19 EKX47617.1 - 5.6e-42 143.8 4.7 7.6e-42 143.3 4.7 1.2 1 0 0 1 1 1 1 MIF4G domain Latarcin PF10279.9 EKX47617.1 - 0.012 16.0 0.1 0.055 13.9 0.1 2.2 1 1 0 1 1 1 0 Latarcin precursor Glyco_hydro_106 PF17132.4 EKX47617.1 - 0.14 10.4 0.0 0.22 9.8 0.0 1.2 1 0 0 1 1 1 0 alpha-L-rhamnosidase FANCI_S2 PF14676.6 EKX47617.1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 FANCI solenoid 2 UPF0242 PF06785.11 EKX47618.1 - 0.0004 20.5 22.1 0.0004 20.5 22.1 4.4 3 1 1 4 4 4 3 Uncharacterised protein family (UPF0242) N-terminus FAM76 PF16046.5 EKX47618.1 - 0.00065 19.1 5.5 0.00065 19.1 5.5 4.0 3 1 1 4 4 4 1 FAM76 protein UPF0020 PF01170.18 EKX47619.1 - 2.9e-18 66.3 0.1 1.4e-17 64.0 0.1 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 AviRa PF11599.8 EKX47619.1 - 0.027 13.9 0.1 11 5.3 0.0 2.8 2 1 1 3 3 3 0 RRNA methyltransferase AviRa Methyltransf_31 PF13847.6 EKX47619.1 - 0.034 13.9 0.0 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 EKX47619.1 - 0.099 13.4 0.1 0.64 10.8 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain Zn_clus PF00172.18 EKX47620.1 - 1.4e-12 47.5 32.9 3.8e-07 30.1 10.9 2.5 2 1 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.26 EKX47621.1 - 9.1e-22 77.4 0.0 4.2e-21 75.3 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EKX47621.1 - 9.3e-13 48.0 0.0 2.1e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EKX47621.1 - 1.1e-09 39.5 0.0 1.8e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EKX47621.1 - 0.079 12.4 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase WD40 PF00400.32 EKX47622.1 - 2.7e-11 43.8 3.3 0.00022 22.0 0.7 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX47622.1 - 0.00048 20.4 0.2 0.13 12.5 0.1 3.8 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_10 PF16685.5 EKX47622.1 - 0.062 13.4 0.7 0.41 10.8 0.1 2.5 2 0 0 2 2 2 0 zinc RING finger of MSL2 RPAP3_C PF13877.6 EKX47622.1 - 0.088 13.3 0.0 0.29 11.7 0.0 1.9 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 4HBT PF03061.22 EKX47623.1 - 0.015 15.7 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily MaoC_dehydratas PF01575.19 EKX47623.1 - 0.033 13.7 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 MaoC like domain 4HBT PF03061.22 EKX47624.1 - 0.073 13.4 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily Kelch_5 PF13854.6 EKX47627.1 - 2.5e-06 27.3 0.5 0.00078 19.4 0.0 3.1 3 1 0 3 3 3 1 Kelch motif Kelch_1 PF01344.25 EKX47627.1 - 1.8e-05 24.2 0.0 0.00095 18.7 0.0 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.6 EKX47627.1 - 0.00013 21.9 0.4 0.0055 16.7 0.0 2.8 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.15 EKX47627.1 - 0.0005 19.9 0.4 0.067 13.2 0.4 2.5 2 1 0 2 2 2 1 Kelch motif Kelch_6 PF13964.6 EKX47627.1 - 0.0052 17.0 0.1 0.22 11.9 0.1 2.7 2 1 0 2 2 2 1 Kelch motif Kelch_3 PF13415.6 EKX47627.1 - 0.28 11.5 9.4 6.7 7.1 2.6 3.6 3 1 0 3 3 3 0 Galactose oxidase, central domain SbsC_C PF18058.1 EKX47628.1 - 0.95 9.7 10.0 0.2 11.9 5.5 2.2 2 1 0 2 2 2 0 SbsC C-terminal domain Glyco_transf_20 PF00982.21 EKX47629.1 - 6.6e-95 318.5 0.0 8.5e-95 318.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EKX47629.1 - 1.9e-49 167.9 0.0 3e-49 167.3 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 EKX47629.1 - 0.095 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase UreE_N PF02814.15 EKX47629.1 - 0.3 10.7 1.8 2.3 7.9 0.1 2.4 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain Asp PF00026.23 EKX47630.1 - 4e-12 46.2 0.0 5.8e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease GMC_oxred_N PF00732.19 EKX47632.1 - 1.1e-28 100.5 0.7 1.4e-14 54.2 0.1 2.5 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 EKX47632.1 - 4.3e-28 98.6 0.0 7.2e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 EKX47632.1 - 0.0078 15.8 0.8 0.043 13.4 0.7 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EKX47632.1 - 0.037 14.2 1.8 0.12 12.6 1.8 1.9 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EKX47632.1 - 0.074 12.3 0.0 0.2 10.9 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EKX47632.1 - 0.31 11.6 1.6 0.65 10.6 1.6 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EKX47632.1 - 2.6 7.0 4.7 5.6 5.9 4.7 1.5 1 0 0 1 1 1 0 FAD binding domain TPR_1 PF00515.28 EKX47633.1 - 7.9e-53 174.2 30.9 2e-08 33.7 0.0 9.8 10 0 0 10 10 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 EKX47633.1 - 7.6e-45 147.4 27.9 9.7e-07 28.5 0.0 10.3 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.6 EKX47633.1 - 7.9e-25 86.3 6.6 7.7e-06 25.5 0.2 8.1 5 2 3 8 8 8 5 TPR repeat STI1 PF17830.1 EKX47633.1 - 1.3e-24 85.8 7.2 1.4e-12 47.3 1.9 2.9 2 0 0 2 2 2 2 STI1 domain TPR_8 PF13181.6 EKX47633.1 - 3.1e-20 70.6 34.2 0.0025 17.9 0.0 10.4 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_12 PF13424.6 EKX47633.1 - 7.7e-19 67.8 7.2 1.9e-05 24.9 0.3 7.4 4 3 1 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 EKX47633.1 - 4.4e-17 61.3 7.3 0.1 13.5 0.0 8.7 7 2 2 9 9 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 EKX47633.1 - 8.6e-17 61.5 3.5 0.0018 18.9 0.0 7.5 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 EKX47633.1 - 1e-15 56.8 5.1 0.16 12.4 0.1 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 EKX47633.1 - 1.1e-14 54.6 5.0 0.091 13.3 0.0 7.2 5 1 2 7 7 7 5 Tetratricopeptide repeat TPR_9 PF13371.6 EKX47633.1 - 8e-09 35.5 0.1 0.12 12.5 0.0 4.8 3 2 2 5 5 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX47633.1 - 1.8e-08 34.5 9.2 0.004 17.3 0.5 4.8 3 2 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 EKX47633.1 - 2.9e-06 27.1 17.3 0.012 15.4 0.3 5.2 3 2 1 4 4 4 2 Tetratricopeptide repeat-like domain TPR_7 PF13176.6 EKX47633.1 - 3.6e-06 26.6 3.9 1.3 9.2 0.0 6.4 7 0 0 7 7 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX47633.1 - 4e-06 26.8 0.2 10 6.2 0.0 5.1 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 EKX47633.1 - 0.00057 20.4 14.0 5.7 7.8 0.0 7.9 9 0 0 9 9 9 1 Tetratricopeptide repeat SPO22 PF08631.10 EKX47633.1 - 0.0035 16.9 2.9 1.5 8.2 0.3 3.4 2 1 1 3 3 3 1 Meiosis protein SPO22/ZIP4 like TPR_3 PF07720.12 EKX47633.1 - 0.016 15.2 11.3 0.073 13.1 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX47633.1 - 0.045 13.6 19.7 1.2 9.1 0.0 7.8 9 0 0 9 9 9 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 EKX47633.1 - 0.16 11.4 5.4 1 8.8 0.0 4.6 6 0 0 6 6 6 0 SHNi-TPR MIT PF04212.18 EKX47633.1 - 1.2 9.2 22.2 0.8 9.8 0.1 6.8 6 1 1 7 7 7 0 MIT (microtubule interacting and transport) domain ABC_membrane_2 PF06472.15 EKX47634.1 - 1e-49 169.4 2.4 1.4e-49 168.9 2.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EKX47634.1 - 3.2e-17 63.3 0.0 6e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SbmA_BacA PF05992.12 EKX47634.1 - 1.2e-10 41.3 1.0 4.5e-10 39.5 1.0 1.7 1 1 0 1 1 1 1 SbmA/BacA-like family ABC_membrane PF00664.23 EKX47634.1 - 1.8e-05 24.5 0.9 2.6e-05 24.0 0.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region RsgA_GTPase PF03193.16 EKX47634.1 - 0.0054 16.6 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EKX47634.1 - 0.017 15.5 0.1 0.039 14.3 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EKX47634.1 - 0.017 15.0 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain SMC_N PF02463.19 EKX47634.1 - 0.095 12.1 2.3 2.9 7.3 0.1 2.4 2 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EKX47634.1 - 0.095 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.6 EKX47634.1 - 0.11 12.1 0.0 0.54 9.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EKX47634.1 - 0.16 11.8 0.3 0.34 10.7 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GST_N_2 PF13409.6 EKX47635.1 - 8.3e-12 45.2 0.0 1.8e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EKX47635.1 - 1.1e-09 38.6 0.0 5e-09 36.5 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EKX47635.1 - 5.8e-07 29.8 0.0 1.8e-05 25.0 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EKX47635.1 - 0.00011 22.1 1.6 0.00012 22.1 0.3 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EKX47635.1 - 0.016 15.4 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain WD40 PF00400.32 EKX47636.1 - 1.7e-22 79.3 4.5 4.2e-09 36.9 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 EKX47636.1 - 9.8e-06 24.5 0.3 0.0092 14.7 0.0 2.7 2 1 1 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EKX47636.1 - 0.00089 19.5 0.2 4.9 7.5 0.0 3.9 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Pex19 PF04614.12 EKX47636.1 - 0.002 18.0 4.0 0.003 17.4 4.0 1.2 1 0 0 1 1 1 1 Pex19 protein family FAD_binding_1 PF00667.20 EKX47637.1 - 5.5e-41 140.6 0.0 7.8e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EKX47637.1 - 9.7e-34 116.6 0.0 1.9e-33 115.7 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EKX47637.1 - 2.3e-06 28.2 0.6 0.0073 16.9 0.0 2.6 1 1 1 2 2 2 2 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EKX47637.1 - 0.03 14.6 0.0 0.076 13.3 0.0 1.7 1 1 0 1 1 1 0 Flavodoxin domain SIS_2 PF13580.6 EKX47637.1 - 0.082 12.9 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 SIS domain Ank_2 PF12796.7 EKX47638.1 - 9.9e-11 42.1 0.0 1.5e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX47638.1 - 7e-10 39.2 0.1 8.8e-07 29.4 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX47638.1 - 7.4e-10 38.8 0.1 0.00041 20.7 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EKX47638.1 - 8.1e-10 38.8 0.8 6.7e-07 29.5 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX47638.1 - 2e-08 33.8 0.0 0.0034 17.8 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat DUF676 PF05057.14 EKX47639.1 - 2.3e-27 95.9 0.1 3.1e-27 95.5 0.1 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EKX47639.1 - 0.059 13.2 0.0 0.11 12.3 0.0 1.4 1 1 0 1 1 1 0 Palmitoyl protein thioesterase Lipase_3 PF01764.25 EKX47639.1 - 0.16 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Pkinase PF00069.25 EKX47640.1 - 6.8e-53 179.7 0.0 1.1e-52 179.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX47640.1 - 2.9e-44 151.3 0.0 4.8e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX47640.1 - 2.4e-12 46.8 0.0 4.2e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EKX47640.1 - 9.9e-05 21.4 0.0 0.00029 19.9 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EKX47640.1 - 0.00014 20.8 0.5 0.00025 20.0 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EKX47640.1 - 0.0018 18.3 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX47640.1 - 0.0047 16.3 0.1 0.009 15.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EKX47640.1 - 0.007 16.0 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.11 EKX47640.1 - 0.0096 15.0 0.1 0.022 13.8 0.1 1.6 1 0 0 1 1 1 1 Seadornavirus VP7 SKI PF01202.22 EKX47641.1 - 6.2e-14 52.4 0.2 1e-13 51.7 0.2 1.4 1 0 0 1 1 1 1 Shikimate kinase TipAS PF07739.13 EKX47641.1 - 0.091 13.3 2.3 1 9.9 0.1 2.7 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain FlaG PF03646.15 EKX47641.1 - 0.35 11.1 2.1 0.36 11.0 0.6 1.7 2 0 0 2 2 2 0 FlaG protein Ank_2 PF12796.7 EKX47642.1 - 4.4e-19 68.9 2.6 7.2e-10 39.3 0.8 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX47642.1 - 3.9e-18 65.6 3.5 4.6e-07 30.3 0.1 3.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX47642.1 - 1.4e-17 61.9 1.1 0.0095 16.4 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EKX47642.1 - 2.2e-15 56.5 2.8 0.00088 19.5 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EKX47642.1 - 1.1e-13 50.9 3.3 0.045 14.2 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat DUF3447 PF11929.8 EKX47642.1 - 0.027 14.4 0.1 7.4 6.6 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3447) Hydrophob_seed PF14547.6 EKX47642.1 - 0.13 12.5 1.2 0.36 11.1 0.4 2.0 1 1 0 2 2 2 0 Hydrophobic seed protein Herpes_UL33 PF03581.13 EKX47642.1 - 0.54 10.7 3.9 12 6.4 0.0 3.4 1 1 2 3 3 3 0 Herpesvirus UL33-like protein KASH_CCD PF14662.6 EKX47643.1 - 0.0031 17.4 14.8 0.0031 17.4 14.8 2.4 3 0 0 3 3 3 1 Coiled-coil region of CCDC155 or KASH MukB PF04310.12 EKX47643.1 - 0.049 13.4 2.1 0.065 13.0 2.1 1.3 1 0 0 1 1 1 0 MukB N-terminal Glyco_hydro_65m PF03632.15 EKX47643.1 - 0.13 11.0 3.5 0.18 10.6 3.5 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65 central catalytic domain Exonuc_VII_L PF02601.15 EKX47643.1 - 0.17 11.4 7.2 0.18 11.4 7.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit FAM76 PF16046.5 EKX47643.1 - 0.37 10.1 21.2 0.046 13.1 16.3 1.7 1 1 1 2 2 2 0 FAM76 protein DUF3106 PF11304.8 EKX47643.1 - 0.81 10.2 8.0 1.6 9.2 1.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) NPV_P10 PF05531.12 EKX47643.1 - 0.92 10.0 10.8 96 3.5 9.1 3.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein PurS PF02700.14 EKX47643.1 - 1.1 9.4 8.8 1 9.5 6.4 2.1 2 0 0 2 2 2 0 Phosphoribosylformylglycinamidine (FGAM) synthase Gly_transf_sug PF04488.15 EKX47643.1 - 1.2 9.8 3.2 26 5.5 3.2 2.7 1 1 0 1 1 1 0 Glycosyltransferase sugar-binding region containing DXD motif DUF1664 PF07889.12 EKX47643.1 - 2.4 8.2 10.3 3.9 7.5 9.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SbcD_C PF12320.8 EKX47643.1 - 2.6 8.4 10.6 1.7 9.0 6.7 2.8 2 1 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Fez1 PF06818.15 EKX47643.1 - 2.9 8.3 26.2 0.024 15.1 16.5 1.9 2 0 0 2 2 2 0 Fez1 Peptidase_S64 PF08192.11 EKX47643.1 - 8.6 4.7 15.4 10 4.4 15.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 Ank_4 PF13637.6 EKX47644.1 - 3.4e-23 81.7 1.3 5.3e-05 23.7 0.0 7.9 5 3 3 8 8 8 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX47644.1 - 1.2e-22 80.3 10.2 5.1e-10 39.8 1.2 5.1 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX47644.1 - 3.3e-16 59.1 1.2 2e-05 24.7 0.0 5.8 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX47644.1 - 3.8e-13 48.3 4.8 0.0044 17.4 0.0 7.9 9 0 0 9 9 9 3 Ankyrin repeat Ank PF00023.30 EKX47644.1 - 1.1e-08 35.1 12.0 0.4 11.2 0.0 7.8 8 1 0 8 8 8 3 Ankyrin repeat EppA_BapA PF07268.11 EKX47644.1 - 0.12 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Exported protein precursor (EppA/BapA) DUF92 PF01940.16 EKX47646.1 - 4.2e-66 222.7 8.8 5e-66 222.5 8.8 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 Pkinase PF00069.25 EKX47647.1 - 1.7e-40 139.1 0.0 2.6e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX47647.1 - 6.1e-19 68.3 0.0 9.7e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX47647.1 - 0.00012 22.1 0.0 0.00021 21.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EKX47647.1 - 0.0061 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase ABC1 PF03109.16 EKX47647.1 - 0.061 13.5 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 ABC1 family adh_short PF00106.25 EKX47648.1 - 7.8e-11 41.8 0.1 1.4e-10 41.0 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EKX47648.1 - 5.9e-07 29.6 0.1 9.2e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EKX47648.1 - 1.2e-05 25.0 0.9 1.9e-05 24.4 0.1 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase TTc_toxin_rep PF18807.1 EKX47648.1 - 0.16 11.8 0.1 0.31 10.9 0.1 1.4 1 0 0 1 1 1 0 Tripartite Tc toxins repeat UPF0242 PF06785.11 EKX47649.1 - 3.8e-06 27.1 2.5 3.8e-06 27.1 2.5 2.0 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus T4SS PF07996.11 EKX47649.1 - 0.13 12.7 9.8 0.37 11.2 7.6 2.3 1 1 1 2 2 2 0 Type IV secretion system proteins DUF3958 PF13125.6 EKX47649.1 - 0.18 12.0 7.4 3.1 8.0 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) DUF4208 PF13907.6 EKX47649.1 - 0.89 10.0 6.4 0.78 10.2 1.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4208) Fib_alpha PF08702.10 EKX47649.1 - 1.1 9.5 11.3 2 8.6 3.5 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF2203 PF09969.9 EKX47649.1 - 1.8 9.3 9.3 0.24 12.1 2.0 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) UPF0242 PF06785.11 EKX47650.1 - 0.017 15.3 9.3 0.016 15.3 7.0 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Phage_GPA PF05840.13 EKX47650.1 - 0.02 14.0 2.6 0.017 14.2 1.0 1.6 1 1 1 2 2 2 0 Bacteriophage replication gene A protein (GPA) Uds1 PF15456.6 EKX47650.1 - 0.027 14.6 11.5 0.72 10.0 4.9 2.4 2 1 0 2 2 2 0 Up-regulated During Septation LPD5 PF18799.1 EKX47650.1 - 0.042 14.3 3.1 0.17 12.3 0.6 2.3 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 5 TipAS PF07739.13 EKX47650.1 - 0.14 12.7 2.8 8.2 7.0 0.1 2.4 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Blo-t-5 PF11642.8 EKX47650.1 - 0.14 12.1 5.3 0.037 14.0 2.1 1.6 2 0 0 2 2 2 0 Mite allergen Blo t 5 MutS_V PF00488.21 EKX47650.1 - 0.29 11.1 1.3 0.99 9.4 0.4 2.1 1 1 1 2 2 2 0 MutS domain V E2F_CC-MB PF16421.5 EKX47650.1 - 2.4 8.6 8.9 0.078 13.3 1.5 2.3 3 0 0 3 3 3 0 E2F transcription factor CC-MB domain Stathmin PF00836.19 EKX47650.1 - 2.6 8.0 12.2 5.4 7.0 4.6 2.5 2 0 0 2 2 2 0 Stathmin family Ank_2 PF12796.7 EKX47651.1 - 1.2e-24 86.6 2.0 4.6e-14 52.8 0.3 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX47651.1 - 7.2e-23 80.4 1.4 7.1e-09 35.8 0.0 4.1 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX47651.1 - 1.1e-21 76.8 0.5 9.3e-08 32.5 0.0 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EKX47651.1 - 3.4e-21 74.7 0.8 5.7e-05 23.4 0.1 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EKX47651.1 - 1.1e-19 68.5 1.1 3.2e-05 24.0 0.1 5.4 5 0 0 5 5 5 4 Ankyrin repeat CDC45 PF02724.14 EKX47652.1 - 0.43 8.8 5.2 0.37 9.0 5.2 1.1 1 0 0 1 1 1 0 CDC45-like protein HeH PF12949.7 EKX47653.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 HeH/LEM domain UVR PF02151.19 EKX47653.1 - 0.023 14.4 2.7 3.2 7.6 2.0 2.6 2 0 0 2 2 2 0 UvrB/uvrC motif DNase-RNase PF02577.14 EKX47653.1 - 0.044 13.4 0.0 0.4 10.3 0.0 2.5 3 0 0 3 3 3 0 Bifunctional nuclease Ish1 PF10281.9 EKX47653.1 - 0.14 12.5 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein DUF1768 PF08719.11 EKX47655.1 - 0.025 14.8 0.0 0.039 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1768) Nop10p PF04135.12 EKX47656.1 - 6.4e-05 22.9 0.1 0.00013 21.9 0.1 1.5 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family AAA_31 PF13614.6 EKX47657.1 - 2.9e-17 63.2 0.5 3.1e-12 46.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain CbiA PF01656.23 EKX47657.1 - 1.1e-11 44.9 1.2 6.8e-11 42.3 1.2 2.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 EKX47657.1 - 0.00017 21.1 0.0 0.0006 19.3 0.0 1.9 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 EKX47657.1 - 0.00039 19.8 0.3 0.0013 18.0 0.0 2.0 3 0 0 3 3 3 1 ATPase MipZ ArsA_ATPase PF02374.15 EKX47657.1 - 0.03 13.5 0.1 0.084 12.0 0.0 1.7 2 0 0 2 2 2 0 Anion-transporting ATPase VirC1 PF07015.11 EKX47657.1 - 0.1 11.9 0.3 5.3 6.3 0.0 2.7 3 0 0 3 3 3 0 VirC1 protein Fer4_NifH PF00142.18 EKX47657.1 - 0.2 11.1 0.1 0.54 9.6 0.0 1.8 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family GCP_C_terminal PF04130.13 EKX47658.1 - 1.2e-51 176.0 0.0 2e-51 175.3 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EKX47658.1 - 8.5e-46 157.0 0.5 1.3e-45 156.4 0.1 1.5 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal PDZ_6 PF17820.1 EKX47659.1 - 5.3e-06 26.2 0.0 9.4e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX47659.1 - 0.0011 19.2 0.0 0.0019 18.5 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX47659.1 - 0.0015 18.5 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Tricorn protease PDZ domain PDZ_2 PF13180.6 EKX47659.1 - 0.017 15.4 0.0 0.027 14.8 0.0 1.4 1 0 0 1 1 1 0 PDZ domain RRM_1 PF00076.22 EKX47660.1 - 1.1e-13 50.8 0.4 8.1e-10 38.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EKX47660.1 - 0.025 14.6 0.1 3.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif PSP1 PF04468.12 EKX47660.1 - 0.074 13.3 0.6 0.19 12.0 0.5 1.7 1 1 0 1 1 1 0 PSP1 C-terminal conserved region Tmemb_14 PF03647.13 EKX47661.1 - 1.9e-15 57.4 9.0 2.3e-15 57.1 9.0 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF4131 PF13567.6 EKX47661.1 - 1.6 8.4 4.3 3.6 7.2 4.3 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF3792 PF12670.7 EKX47661.1 - 2.1 8.5 13.8 39 4.5 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3792) ANAPC5 PF12862.7 EKX47662.1 - 7.8e-25 86.8 2.2 7.8e-25 86.8 2.2 2.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 EKX47662.1 - 1.1e-05 25.7 7.7 0.002 18.4 1.8 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX47662.1 - 0.00052 19.8 0.5 0.11 12.4 0.3 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX47662.1 - 0.0008 19.4 2.2 0.23 11.8 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX47662.1 - 0.026 14.4 5.5 0.089 12.7 0.2 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EKX47662.1 - 0.026 14.5 1.8 0.13 12.3 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EKX47662.1 - 0.21 11.8 4.0 1.1 9.5 0.6 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 EKX47662.1 - 0.49 11.1 8.3 7.3 7.3 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX47662.1 - 1.2 10.1 8.3 6.8 7.8 0.9 5.0 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX47662.1 - 4.1 8.2 5.1 4.8 8.0 0.4 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DEAD PF00270.29 EKX47663.1 - 2.6e-42 144.6 0.1 4.8e-42 143.7 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX47663.1 - 5.4e-31 107.2 0.1 3.3e-30 104.7 0.1 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX47663.1 - 0.00015 21.9 0.0 0.00023 21.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EKX47663.1 - 0.011 16.1 0.1 0.017 15.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EKX47663.1 - 0.016 15.0 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 EKX47663.1 - 0.031 14.2 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 Helicase CMS1 PF14617.6 EKX47663.1 - 0.056 12.8 0.5 0.26 10.6 0.0 2.0 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit tRNA-synt_1b PF00579.25 EKX47663.1 - 0.066 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) Armet PF10208.9 EKX47664.1 - 0.011 15.7 0.6 3.9 7.4 0.1 2.4 1 1 1 2 2 2 0 Degradation arginine-rich protein for mis-folding SHNi-TPR PF10516.9 EKX47664.1 - 0.067 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 SHNi-TPR baeRF_family2 PF18844.1 EKX47665.1 - 0.00081 19.5 1.8 0.00082 19.5 0.6 1.6 1 1 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 2 SAP PF02037.27 EKX47665.1 - 0.011 15.5 4.6 0.47 10.3 0.7 2.9 2 1 1 3 3 3 0 SAP domain Lipoprotein_16 PF03923.13 EKX47665.1 - 0.17 11.5 0.0 0.25 11.0 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized lipoprotein Metallophos PF00149.28 EKX47666.1 - 2.8e-21 76.9 0.3 3.8e-21 76.5 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PhoD PF09423.10 EKX47666.1 - 1.2e-05 24.5 0.0 0.00052 19.1 0.0 2.1 2 0 0 2 2 2 2 PhoD-like phosphatase Metallophos_2 PF12850.7 EKX47666.1 - 0.0021 18.3 0.0 0.095 12.9 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aminotran_1_2 PF00155.21 EKX47667.1 - 1.3e-17 64.0 0.0 9.8e-17 61.2 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II Cupin_8 PF13621.6 EKX47668.1 - 1.2e-29 103.8 0.0 1.4e-29 103.5 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain FPP PF05911.11 EKX47669.1 - 9.1e-05 20.9 11.5 9.1e-05 20.9 11.5 3.3 2 1 1 3 3 3 2 Filament-like plant protein, long coiled-coil DUF812 PF05667.11 EKX47669.1 - 0.00036 19.6 16.4 0.00036 19.6 16.4 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.12 EKX47669.1 - 0.012 15.7 0.1 0.012 15.7 0.1 6.4 3 2 1 5 5 5 0 TPR/MLP1/MLP2-like protein Wzy_C PF04932.15 EKX47669.1 - 0.039 13.6 0.0 0.082 12.5 0.0 1.6 1 0 0 1 1 1 0 O-Antigen ligase DUF2070 PF09843.9 EKX47669.1 - 0.27 9.5 9.8 0.63 8.3 9.8 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Trypan_PARP PF05887.11 EKX47671.1 - 0.21 11.6 16.2 0.26 11.3 16.2 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NOA36 PF06524.12 EKX47671.1 - 5.6 6.2 15.8 7.5 5.8 15.8 1.3 1 0 0 1 1 1 0 NOA36 protein FERM_M PF00373.18 EKX47672.1 - 0.045 14.2 0.2 0.083 13.3 0.1 1.4 1 1 0 1 1 1 0 FERM central domain Cucumo_2B PF03263.13 EKX47672.1 - 0.18 12.2 1.5 0.18 12.3 0.6 1.5 1 1 0 1 1 1 0 Cucumovirus protein 2B DEAD_assoc PF08494.11 EKX47673.1 - 0.078 12.8 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 DEAD/H associated PPR_2 PF13041.6 EKX47674.1 - 1.2e-06 28.6 0.2 0.17 12.1 0.0 4.2 4 0 0 4 4 4 2 PPR repeat family PPR_3 PF13812.6 EKX47674.1 - 0.0005 20.1 0.2 1.3 9.1 0.0 3.6 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 EKX47674.1 - 0.057 13.1 0.2 3 7.6 0.0 2.8 2 0 0 2 2 2 0 PPR repeat Ephrin_rec_like PF07699.13 EKX47675.1 - 1.8e-09 37.2 47.9 3.6e-08 33.0 10.8 4.6 3 1 1 4 4 4 3 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX47675.1 - 6.3e-07 29.7 5.7 6.3e-07 29.7 5.7 6.5 2 2 5 7 7 7 4 TNFR/NGFR cysteine-rich region DUF2830 PF11125.8 EKX47675.1 - 0.21 11.6 0.5 0.39 10.7 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2830) ThiF PF00899.21 EKX47676.1 - 4.6e-19 68.8 0.1 1e-18 67.6 0.1 1.5 1 1 0 1 1 1 1 ThiF family EF-hand_7 PF13499.6 EKX47677.1 - 1.3e-13 51.2 2.4 2.4e-12 47.1 0.9 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX47677.1 - 1e-12 46.6 4.4 1.2e-06 27.6 0.1 3.5 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 EKX47677.1 - 8.7e-12 44.0 1.0 1e-05 25.0 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 EKX47677.1 - 5.1e-05 23.0 4.8 0.021 14.7 0.7 3.4 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX47677.1 - 7.7e-05 22.0 0.6 0.00043 19.6 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 EKX47677.1 - 0.0025 18.1 0.0 0.0056 17.0 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain Sigma54_CBD PF04963.13 EKX47677.1 - 0.026 14.4 0.7 0.29 11.0 0.2 2.3 1 1 1 2 2 2 0 Sigma-54 factor, core binding domain SKA1 PF07160.12 EKX47677.1 - 0.076 12.9 1.3 0.17 11.7 1.2 1.6 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF3349 PF11829.8 EKX47677.1 - 0.081 13.7 0.7 1.4 9.8 0.1 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF3349) DUF2428 PF10350.9 EKX47677.1 - 0.093 12.0 1.4 0.13 11.5 1.1 1.4 1 1 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) Lip_A_acyltrans PF03279.13 EKX47677.1 - 0.1 11.7 0.3 1.8 7.7 0.1 2.0 1 1 1 2 2 2 0 Bacterial lipid A biosynthesis acyltransferase Spore_III_AB PF09548.10 EKX47677.1 - 0.12 12.4 3.6 0.38 10.9 0.7 2.5 2 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) EF-hand_4 PF12763.7 EKX47677.1 - 0.16 11.9 1.8 1.4 8.9 0.1 2.6 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand CPG4 PF15481.6 EKX47677.1 - 0.3 11.7 4.7 0.25 12.0 2.3 2.1 2 1 0 2 2 2 0 Chondroitin proteoglycan 4 NuiA PF07924.11 EKX47677.1 - 0.64 10.4 3.1 0.86 10.0 0.2 2.5 1 1 2 3 3 3 0 Nuclease A inhibitor-like protein PEGSRP PF07623.11 EKX47678.1 - 0.82 9.5 3.5 4.6 7.2 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1584) NHL PF01436.21 EKX47679.1 - 2.4e-12 46.2 1.4 0.0015 18.5 0.0 5.2 6 0 0 6 6 6 4 NHL repeat SGL PF08450.12 EKX47679.1 - 0.0097 15.5 0.1 1.8 8.1 0.0 2.9 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Synuclein PF01387.17 EKX47679.1 - 0.15 12.3 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Synuclein PfkB PF00294.24 EKX47680.1 - 1.2e-50 172.6 0.7 2.7e-49 168.1 0.7 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EKX47680.1 - 3.2e-06 26.7 0.0 5.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TIG PF01833.24 EKX47681.1 - 0.003 17.6 0.2 0.18 11.9 0.0 4.2 4 0 0 4 4 4 1 IPT/TIG domain Phage_spike PF18715.1 EKX47681.1 - 0.26 11.4 1.4 2.2 8.4 0.0 3.4 3 0 0 3 3 3 0 Phage spike trimer IFT20 PF14931.6 EKX47682.1 - 0.0096 16.1 1.1 0.0096 16.1 1.1 2.9 3 0 0 3 3 3 1 Intraflagellar transport complex B, subunit 20 BST2 PF16716.5 EKX47684.1 - 0.17 12.5 2.7 0.33 11.6 2.7 1.5 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 HAD_2 PF13419.6 EKX47686.1 - 2.7e-13 50.4 0.0 5.8e-13 49.3 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EKX47686.1 - 6.3e-09 36.4 0.0 2.1e-08 34.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EKX47686.1 - 0.12 12.5 0.0 1 9.5 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EKX47686.1 - 0.15 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 HAD-hyrolase-like APH PF01636.23 EKX47687.1 - 2.8e-44 151.8 0.0 4.3e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EKX47687.1 - 1.4e-06 27.9 0.0 2.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.14 EKX47687.1 - 0.00062 19.1 0.0 0.0047 16.2 0.0 2.2 1 1 0 1 1 1 1 Fructosamine kinase RIO1 PF01163.22 EKX47687.1 - 0.00077 19.1 0.0 0.018 14.6 0.0 2.3 2 0 0 2 2 2 1 RIO1 family DUF1679 PF07914.11 EKX47687.1 - 0.0019 17.2 0.0 0.0027 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 EKX47687.1 - 0.0035 17.0 0.0 0.0061 16.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF3848 PF12959.7 EKX47687.1 - 0.086 12.9 0.0 0.22 11.6 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3848) UbiA PF01040.18 EKX47689.1 - 2e-27 96.1 13.4 2.3e-27 95.9 13.4 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family Methyltransf_16 PF10294.9 EKX47690.1 - 2.5e-08 33.9 0.0 4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 EKX47690.1 - 0.063 14.0 0.1 0.8 10.4 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain PDZ_6 PF17820.1 EKX47691.1 - 0.00032 20.5 0.5 0.00091 19.0 0.1 2.0 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX47691.1 - 0.01 16.1 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 PDZ domain AAA_22 PF13401.6 EKX47691.1 - 0.065 13.5 0.1 0.3 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EKX47691.1 - 0.076 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF3456 PF11938.8 EKX47691.1 - 4.9 7.6 12.5 0.083 13.4 1.5 2.9 3 0 0 3 3 3 0 TLR4 regulator and MIR-interacting MSAP tRNA-synt_2 PF00152.20 EKX47693.1 - 1.1e-68 231.7 0.0 1.3e-68 231.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EKX47693.1 - 4e-06 26.7 0.0 6.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EKX47693.1 - 0.0062 16.1 0.0 2.8 7.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) PEX-2N PF09263.10 EKX47693.1 - 0.011 16.0 0.6 0.31 11.4 0.1 2.6 2 0 0 2 2 2 0 Peroxisome biogenesis factor 1, N-terminal Spore_coat_CotO PF14153.6 EKX47695.1 - 1.1 9.2 14.0 1.2 9.0 14.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Aldedh PF00171.22 EKX47697.1 - 1.3e-112 376.7 2.0 1.5e-110 369.9 2.0 2.2 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Gla PF00594.20 EKX47697.1 - 1.7 8.9 4.5 0.34 11.1 0.7 1.8 2 0 0 2 2 2 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain Nsp1_C PF05064.13 EKX47698.1 - 0.01 15.7 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 0 Nsp1-like C-terminal region DUF63 PF01889.17 EKX47699.1 - 0.12 12.5 0.0 0.13 12.4 0.0 1.0 1 0 0 1 1 1 0 Membrane protein of unknown function DUF63 Zw10 PF06248.13 EKX47700.1 - 0.011 14.3 5.4 0.016 13.8 5.4 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 DUF3287 PF11690.8 EKX47700.1 - 0.099 12.4 1.3 1.6 8.5 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3287) DUF1664 PF07889.12 EKX47700.1 - 0.11 12.5 5.0 0.79 9.8 1.2 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DASH_Dam1 PF08653.10 EKX47700.1 - 0.34 10.7 1.1 8.8 6.2 0.2 3.2 3 0 0 3 3 3 0 DASH complex subunit Dam1 CENP-F_leu_zip PF10473.9 EKX47700.1 - 0.36 10.9 17.5 2.6 8.1 17.2 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.9 EKX47700.1 - 0.42 10.9 8.7 0.29 11.4 0.7 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CorA PF01544.18 EKX47700.1 - 0.59 9.4 4.1 0.58 9.4 2.9 1.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Pkip-1 PF06878.11 EKX47700.1 - 0.75 9.9 8.2 1.8 8.6 0.3 2.2 1 1 1 2 2 2 0 Pkip-1 protein ABC_tran_CTD PF16326.5 EKX47700.1 - 0.77 10.0 18.9 0.067 13.5 2.0 3.5 2 1 1 3 3 3 0 ABC transporter C-terminal domain V_ATPase_I PF01496.19 EKX47700.1 - 0.78 7.6 6.8 1 7.2 6.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2730 PF10805.8 EKX47700.1 - 0.8 9.8 5.4 1.3 9.1 0.4 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF2730) Laminin_II PF06009.12 EKX47700.1 - 0.96 9.5 9.6 0.41 10.6 1.0 2.3 1 1 1 2 2 2 0 Laminin Domain II Fib_alpha PF08702.10 EKX47700.1 - 1.5 9.0 6.4 1.1 9.4 0.5 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family I_LWEQ PF01608.17 EKX47700.1 - 2.3 8.5 8.8 4.4 7.5 8.8 1.4 1 0 0 1 1 1 0 I/LWEQ domain Dynactin_p22 PF07426.11 EKX47700.1 - 3.3 7.5 12.3 15 5.4 11.2 2.5 1 1 1 2 2 2 0 Dynactin subunit p22 CEP209_CC5 PF16574.5 EKX47700.1 - 3.8 7.7 14.9 2.5 8.3 9.1 2.4 1 1 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 TMPIT PF07851.13 EKX47700.1 - 4.5 6.4 6.5 1.2 8.3 1.2 1.8 1 1 1 2 2 2 0 TMPIT-like protein ACCA PF03255.14 EKX47700.1 - 4.5 7.1 9.6 10 6.0 1.8 2.8 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit LUC7 PF03194.15 EKX47701.1 - 1.1e-58 198.9 5.8 2e-58 198.0 5.8 1.4 1 0 0 1 1 1 1 LUC7 N_terminus AAA_23 PF13476.6 EKX47701.1 - 0.011 16.3 1.2 0.011 16.3 1.2 2.0 2 1 0 2 2 2 0 AAA domain Peptidase_M75 PF09375.10 EKX47701.1 - 0.015 14.8 0.5 0.026 14.0 0.5 1.4 1 0 0 1 1 1 0 Imelysin Ion_trans_2 PF07885.16 EKX47702.1 - 5.8e-19 67.8 27.8 1.1e-10 41.4 7.6 3.9 3 2 0 3 3 3 2 Ion channel Ion_trans PF00520.31 EKX47702.1 - 4.9e-09 35.8 20.5 1.9e-05 24.0 3.7 2.8 2 0 0 2 2 2 2 Ion transport protein SK_channel PF03530.14 EKX47702.1 - 1.6e-08 34.5 1.8 0.0051 16.8 0.0 3.6 3 1 0 3 3 3 2 Calcium-activated SK potassium channel Lig_chan PF00060.26 EKX47702.1 - 0.00046 20.1 7.3 0.0019 18.1 4.7 3.6 3 1 0 3 3 3 2 Ligand-gated ion channel DDHD PF02862.17 EKX47702.1 - 0.15 12.2 7.3 0.086 13.0 0.2 2.2 2 0 0 2 2 2 0 DDHD domain Spt20 PF12090.8 EKX47702.1 - 0.88 9.1 19.8 1.8 8.1 19.8 1.4 1 0 0 1 1 1 0 Spt20 family Pex14_N PF04695.13 EKX47702.1 - 1.3 9.7 10.1 0.069 13.8 4.0 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF719 PF05334.13 EKX47702.1 - 3.5 7.8 13.5 0.95 9.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Protamine_3 PF08188.11 EKX47702.1 - 6.4 7.1 9.0 31 4.9 0.6 3.1 2 0 0 2 2 2 0 Spermatozal protamine family HATPase_c PF02518.26 EKX47704.1 - 2.3e-21 76.4 0.1 4.1e-21 75.6 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EKX47704.1 - 5.7e-16 58.3 0.1 1.1e-15 57.4 0.1 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EKX47704.1 - 0.00076 19.3 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3921 PF13060.6 EKX47704.1 - 0.017 15.1 0.1 0.03 14.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) HATPase_c_2 PF13581.6 EKX47704.1 - 0.021 14.8 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Trp_ring PF18669.1 EKX47704.1 - 0.14 12.4 0.8 0.27 11.4 0.8 1.5 1 0 0 1 1 1 0 Trimeric autotransporter adhesin Trp ring domain Response_reg PF00072.24 EKX47705.1 - 1.2e-27 96.3 0.0 1.3e-27 96.2 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain DUF99 PF01949.16 EKX47705.1 - 0.075 12.4 0.0 0.089 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF99 Guanylate_cyc PF00211.20 EKX47706.1 - 4.5e-60 202.4 0.4 5.3e-60 202.2 0.4 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ion_trans PF00520.31 EKX47707.1 - 1.5e-10 40.7 17.6 1.5e-10 40.7 17.6 2.1 2 1 0 2 2 2 1 Ion transport protein PKD_channel PF08016.12 EKX47707.1 - 4.6e-09 35.5 25.5 1.3e-06 27.3 12.6 4.5 2 2 1 4 4 4 3 Polycystin cation channel TIP39 PF14980.6 EKX47709.1 - 0.17 11.8 0.2 5.9 6.9 0.1 2.3 2 0 0 2 2 2 0 TIP39 peptide DUF2721 PF11026.8 EKX47710.1 - 0.033 14.1 0.0 0.091 12.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) CCDC-167 PF15188.6 EKX47710.1 - 0.98 9.8 5.0 4 7.9 0.9 3.1 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 CorA PF01544.18 EKX47711.1 - 1.5e-06 27.8 0.3 2.7e-06 26.9 0.3 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein TcdA_TcdB PF12919.7 EKX47711.1 - 0.00086 18.7 2.2 0.0043 16.4 2.2 2.0 1 1 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Kinocilin PF15033.6 EKX47711.1 - 0.37 10.4 0.1 0.37 10.4 0.1 2.0 2 0 0 2 2 2 0 Kinocilin protein SAP PF02037.27 EKX47712.1 - 4.5e-11 42.2 0.8 4.5e-11 42.2 0.8 3.0 3 0 0 3 3 3 1 SAP domain HeH PF12949.7 EKX47712.1 - 0.026 14.2 0.1 0.12 12.2 0.1 2.2 1 0 0 1 1 1 0 HeH/LEM domain LRR_4 PF12799.7 EKX47713.1 - 9.4e-12 45.0 0.9 1.7e-05 25.1 0.4 3.2 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX47713.1 - 5.7e-08 32.4 0.6 0.00041 20.0 0.5 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_9 PF14580.6 EKX47713.1 - 3.4e-06 26.7 0.1 1e-05 25.1 0.1 1.6 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 EKX47713.1 - 0.015 15.3 2.0 3.4 8.0 0.1 3.6 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 EKX47713.1 - 0.016 15.7 3.3 29 5.8 0.1 4.3 4 1 1 5 5 5 0 Leucine Rich Repeat DUF3318 PF11780.8 EKX47713.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3318) NDUF_B6 PF09782.9 EKX47713.1 - 0.14 12.2 2.5 8.4 6.5 0.1 2.1 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit DUF4075 PF13294.6 EKX47713.1 - 0.19 11.9 0.0 1.6 9.0 0.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4075) EGF_2 PF07974.13 EKX47714.1 - 8.4e-45 150.8 225.3 7.9e-05 22.9 8.7 14.4 12 3 1 13 13 13 13 EGF-like domain EGF_Tenascin PF18720.1 EKX47714.1 - 9.4e-27 92.6 224.5 3.1e-06 27.1 16.0 14.7 14 1 0 14 14 14 11 Tenascin EGF domain hEGF PF12661.7 EKX47714.1 - 1.4e-06 28.7 173.2 0.0088 16.6 6.9 15.1 13 0 0 13 13 13 10 Human growth factor-like EGF EGF PF00008.27 EKX47714.1 - 0.00026 21.2 187.1 0.029 14.7 6.9 14.8 14 2 0 14 14 14 8 EGF-like domain I-EGF_1 PF18372.1 EKX47714.1 - 0.036 14.1 2.5 0.036 14.1 2.5 15.7 15 2 0 15 15 15 0 Integrin beta epidermal growth factor like domain 1 Kinesin PF00225.23 EKX47715.1 - 3.4e-108 361.5 0.1 5.4e-108 360.9 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX47715.1 - 1.2e-28 100.0 0.0 1.8e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding AAA_22 PF13401.6 EKX47717.1 - 1.9e-05 24.9 0.1 0.00026 21.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EKX47717.1 - 0.0001 22.7 0.0 0.00022 21.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX47717.1 - 0.00012 22.5 0.2 0.00092 19.6 0.0 2.3 2 1 0 3 3 2 1 AAA ATPase domain AAA_25 PF13481.6 EKX47717.1 - 0.00021 20.9 0.0 0.0057 16.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 EKX47717.1 - 0.00028 20.5 0.0 0.00047 19.7 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 TniB PF05621.11 EKX47717.1 - 0.00039 19.9 0.1 0.0026 17.2 0.1 2.2 1 1 0 1 1 1 1 Bacterial TniB protein AAA_14 PF13173.6 EKX47717.1 - 0.0033 17.5 0.0 0.018 15.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain TK PF00265.18 EKX47717.1 - 0.0036 17.2 0.1 0.016 15.1 0.1 1.9 1 1 0 1 1 1 1 Thymidine kinase AAA_30 PF13604.6 EKX47717.1 - 0.0058 16.4 0.0 0.032 14.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 EKX47717.1 - 0.0074 15.4 0.3 0.016 14.2 0.3 1.6 1 1 0 1 1 1 1 Type II/IV secretion system protein AAA_24 PF13479.6 EKX47717.1 - 0.01 15.6 0.0 0.022 14.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EKX47717.1 - 0.011 15.6 0.0 5.6 6.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EKX47717.1 - 0.011 15.7 0.0 0.077 12.9 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 EKX47717.1 - 0.013 15.5 0.0 0.061 13.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EKX47717.1 - 0.014 15.8 0.0 1.4 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EKX47717.1 - 0.017 14.5 0.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 KaiC Glyco_transf_4 PF13439.6 EKX47717.1 - 0.018 15.1 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 AAA_7 PF12775.7 EKX47717.1 - 0.026 14.0 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 EKX47717.1 - 0.031 14.4 0.0 0.07 13.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 EKX47717.1 - 0.033 13.5 0.2 0.19 11.0 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family CobA_CobO_BtuR PF02572.15 EKX47717.1 - 0.035 14.4 0.0 0.073 13.3 0.0 1.5 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP TrwB_AAD_bind PF10412.9 EKX47717.1 - 0.038 12.9 0.0 0.091 11.7 0.0 1.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 EKX47717.1 - 0.045 13.0 0.0 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin GGDEF_2 PF17853.1 EKX47717.1 - 0.045 14.0 0.3 1.1 9.5 0.1 2.6 2 1 0 2 2 2 0 GGDEF-like domain AAA_18 PF13238.6 EKX47717.1 - 0.048 14.2 0.0 0.17 12.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain DnaB_C PF03796.15 EKX47717.1 - 0.05 12.9 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain NTPase_1 PF03266.15 EKX47717.1 - 0.06 13.3 0.1 3.8 7.4 0.0 2.3 2 0 0 2 2 2 0 NTPase FA_desaturase PF00487.24 EKX47718.1 - 2.8e-24 86.3 21.6 2.8e-24 86.3 21.6 1.8 2 1 0 2 2 2 1 Fatty acid desaturase FA_hydroxylase PF04116.13 EKX47718.1 - 0.014 15.8 0.6 0.014 15.8 0.6 3.4 3 1 1 4 4 4 0 Fatty acid hydroxylase superfamily RWP-RK PF02042.15 EKX47720.1 - 4.9e-23 80.8 0.1 8.7e-23 80.0 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_6 PF01418.17 EKX47720.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.5 1 1 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_Mga PF08280.11 EKX47720.1 - 0.052 13.6 0.0 0.089 12.8 0.0 1.3 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_17 PF12728.7 EKX47720.1 - 0.065 13.4 0.0 0.24 11.6 0.0 1.9 1 1 1 2 2 2 0 Helix-turn-helix domain IMD PF08397.11 EKX47720.1 - 0.084 12.2 0.0 0.09 12.1 0.0 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain NUMOD1 PF07453.13 EKX47720.1 - 0.14 12.5 0.0 0.76 10.1 0.0 2.1 1 1 1 2 2 2 0 NUMOD1 domain LRR_4 PF12799.7 EKX47721.1 - 4.8e-08 33.2 0.3 0.0017 18.7 0.0 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX47721.1 - 1.7e-07 30.9 0.2 3.4e-07 29.9 0.2 1.4 1 0 0 1 1 1 1 Leucine rich repeat LRRNT_2 PF08263.12 EKX47721.1 - 0.00029 21.1 1.6 0.00092 19.5 1.6 1.9 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 EKX47721.1 - 0.0078 16.2 0.3 1.4 9.2 0.0 3.3 3 0 0 3 3 3 1 Leucine Rich repeat LRR_1 PF00560.33 EKX47721.1 - 0.0088 16.5 1.9 8.3 7.4 0.0 4.0 3 0 0 3 3 3 1 Leucine Rich Repeat Lectin_C PF00059.21 EKX47722.1 - 5.2e-08 33.6 5.6 0.00012 22.8 0.9 2.8 2 0 0 2 2 2 2 Lectin C-type domain DUF4215 PF13948.6 EKX47722.1 - 9.9e-06 25.9 3.9 9.9e-06 25.9 3.9 4.2 4 0 0 4 4 4 1 Domain of unknown function (DUF4215) EGF_3 PF12947.7 EKX47722.1 - 0.00025 21.2 8.6 0.00025 21.2 8.6 5.2 5 1 0 5 5 5 2 EGF domain hEGF PF12661.7 EKX47722.1 - 0.00035 21.1 2.5 0.00035 21.1 2.5 6.0 5 1 1 6 6 6 1 Human growth factor-like EGF EGF PF00008.27 EKX47722.1 - 0.00063 20.0 7.3 0.00063 20.0 7.3 4.8 5 1 0 5 5 5 1 EGF-like domain Chordopox_A33R PF05966.12 EKX47722.1 - 0.0026 17.0 3.7 0.037 13.3 0.2 2.4 2 0 0 2 2 2 2 Chordopoxvirus A33R protein Pkinase PF00069.25 EKX47723.1 - 1.3e-70 237.8 0.0 1.4e-70 237.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX47723.1 - 1.2e-38 132.9 0.0 1.4e-38 132.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX47723.1 - 1.2e-05 24.3 0.0 1.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EKX47723.1 - 9.8e-05 21.8 0.0 0.00017 21.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EKX47723.1 - 0.0039 16.5 0.0 0.0061 15.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EKX47723.1 - 0.03 14.2 0.1 0.1 12.5 0.0 1.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family EcKinase PF02958.20 EKX47723.1 - 0.073 12.4 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase TPR_1 PF00515.28 EKX47724.1 - 3.6e-21 74.0 4.0 3.2e-06 26.7 0.1 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX47724.1 - 2e-20 71.2 2.4 3.5e-06 26.7 0.1 3.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX47724.1 - 1.1e-15 56.5 0.8 0.00032 20.7 0.0 3.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX47724.1 - 5.8e-13 48.3 7.1 0.00013 21.5 0.1 4.0 2 2 2 4 4 4 4 TPR repeat TPR_9 PF13371.6 EKX47724.1 - 3.8e-09 36.6 0.1 5.1e-06 26.5 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX47724.1 - 4.4e-09 36.5 2.6 2.1e-05 24.7 0.3 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX47724.1 - 6.5e-07 29.0 4.3 0.24 11.3 0.1 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 EKX47724.1 - 8.6e-07 28.9 5.6 0.0036 17.6 0.1 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX47724.1 - 8.4e-06 26.2 0.3 0.066 14.1 0.1 3.1 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX47724.1 - 1.1e-05 26.0 0.4 0.00018 22.1 0.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX47724.1 - 7.2e-05 22.5 2.2 0.098 12.7 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX47724.1 - 0.00028 21.3 0.6 1 10.1 0.2 3.3 2 1 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX47724.1 - 0.0013 18.9 0.1 0.03 14.6 0.0 1.9 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EKX47724.1 - 0.003 18.0 0.3 0.38 11.3 0.1 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat NARP1 PF12569.8 EKX47724.1 - 0.029 13.3 0.1 0.053 12.4 0.0 1.4 1 1 0 1 1 1 0 NMDA receptor-regulated protein 1 Vwaint PF14624.6 EKX47724.1 - 0.049 13.8 0.1 15 5.8 0.0 2.9 3 0 0 3 3 3 0 VWA / Hh protein intein-like DUF3856 PF12968.7 EKX47724.1 - 0.074 13.1 0.5 1.2 9.1 0.5 2.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_1 PF00515.28 EKX47725.1 - 2.5e-40 134.7 20.8 1.1e-08 34.6 0.4 7.1 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 EKX47725.1 - 7.2e-35 116.3 12.6 7.6e-07 28.8 0.3 6.9 6 1 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 EKX47725.1 - 3.3e-34 116.3 12.0 1.1e-07 31.4 0.5 6.2 2 2 4 6 6 6 6 TPR repeat TPR_8 PF13181.6 EKX47725.1 - 1.1e-26 90.8 16.1 6e-06 26.1 0.7 6.8 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 EKX47725.1 - 1.3e-21 76.6 3.9 4.4e-06 26.9 0.0 5.4 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.6 EKX47725.1 - 1.4e-18 65.8 6.8 0.00025 21.2 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 EKX47725.1 - 3.4e-17 62.8 0.0 1.8e-05 25.3 0.0 3.3 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 EKX47725.1 - 1.9e-14 53.6 0.0 0.00013 22.0 0.0 4.0 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 EKX47725.1 - 4e-14 52.2 4.0 0.25 12.0 0.0 6.4 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 EKX47725.1 - 3.3e-12 45.5 4.1 0.09 12.9 0.0 6.3 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX47725.1 - 1e-09 38.7 2.1 0.007 16.9 0.1 3.8 3 1 2 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX47725.1 - 9.6e-07 28.9 5.0 0.035 14.3 2.3 3.2 1 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EKX47725.1 - 1.2e-06 28.0 0.1 0.42 9.8 0.1 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX47725.1 - 4.9e-06 26.2 3.5 0.44 10.5 0.0 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat NARP1 PF12569.8 EKX47725.1 - 0.00025 20.1 5.5 0.019 13.9 0.2 2.6 1 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 EKX47725.1 - 0.0013 19.1 0.3 0.053 13.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat HTH_Bact PF18768.1 EKX47725.1 - 0.0022 17.5 11.7 11 5.7 0.0 5.3 5 0 0 5 5 5 0 Helix-turn-helix bacterial domain TPR_14 PF13428.6 EKX47725.1 - 0.0023 18.6 0.0 40 5.4 0.0 4.9 2 2 3 5 5 5 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 EKX47725.1 - 0.008 15.6 5.8 0.67 9.5 0.0 4.7 6 0 0 6 6 5 1 SHNi-TPR PA28_beta PF02252.18 EKX47725.1 - 0.014 15.1 2.5 1.5 8.5 0.4 3.2 2 2 1 3 3 3 0 Proteasome activator pa28 beta subunit BTAD PF03704.17 EKX47725.1 - 0.02 15.3 0.0 1.7 9.1 0.0 2.8 1 1 1 2 2 2 0 Bacterial transcriptional activator domain DUF4810 PF16068.5 EKX47725.1 - 0.025 15.1 1.5 1.7 9.2 0.0 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF4810) RPN7 PF10602.9 EKX47725.1 - 0.069 12.9 4.2 3.4 7.3 0.0 3.6 2 1 2 4 4 4 0 26S proteasome subunit RPN7 SH3BP5 PF05276.14 EKX47725.1 - 0.28 11.0 4.0 0.53 10.0 2.1 2.3 2 1 0 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) MIT PF04212.18 EKX47725.1 - 0.5 10.5 12.6 20 5.4 0.6 5.4 5 1 1 6 6 5 0 MIT (microtubule interacting and transport) domain DUF357 PF04010.13 EKX47725.1 - 4 7.6 7.8 39 4.4 0.1 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF357) cNMP_binding PF00027.29 EKX47726.1 - 1.6e-12 47.3 0.0 4.9e-12 45.8 0.0 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Arm PF00514.23 EKX47726.1 - 0.02 14.9 0.2 11 6.2 0.0 3.7 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat XAP5 PF04921.14 EKX47728.1 - 1.2e-74 251.3 16.2 1.2e-74 251.3 16.2 2.0 1 1 1 2 2 2 1 XAP5, circadian clock regulator DUF1265 PF06887.14 EKX47728.1 - 0.29 11.1 1.0 0.74 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1265) WD40 PF00400.32 EKX47729.1 - 3.3e-22 78.3 6.2 6.9e-06 26.7 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX47729.1 - 1.2e-10 41.5 1.0 1.5 9.2 0.1 5.8 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EKX47729.1 - 0.034 13.7 0.8 0.25 10.9 0.3 2.5 2 1 0 3 3 3 0 PQQ-like domain eIF2A PF08662.11 EKX47729.1 - 0.098 12.5 0.0 1.8 8.4 0.0 2.8 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Rav1p_C PF12234.8 EKX47729.1 - 0.21 9.9 0.0 0.37 9.1 0.0 1.3 1 0 0 1 1 1 0 RAVE protein 1 C terminal PDZ_6 PF17820.1 EKX47730.1 - 0.00025 20.8 0.2 0.13 12.1 0.1 2.9 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX47730.1 - 0.00083 19.6 0.0 0.8 10.1 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 EKX47730.1 - 0.0072 16.6 0.1 2.1 8.8 0.2 2.5 2 0 0 2 2 2 2 PDZ domain Aldose_epim PF01263.20 EKX47731.1 - 9.2e-35 120.4 0.0 1.3e-34 119.9 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase UCH PF00443.29 EKX47732.1 - 1.8e-31 109.6 0.0 4e-28 98.6 0.0 2.4 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EKX47732.1 - 5e-07 29.6 0.9 0.00018 21.2 0.5 3.5 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-RanBP PF00641.18 EKX47732.1 - 0.1 11.9 2.0 0.16 11.4 0.2 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others UPF0242 PF06785.11 EKX47733.1 - 0.00029 21.0 1.1 0.00049 20.3 1.1 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus MbeD_MobD PF04899.12 EKX47733.1 - 0.0093 16.1 3.8 0.17 12.0 0.0 3.0 2 2 1 3 3 3 1 MbeD/MobD like DUF4618 PF15397.6 EKX47733.1 - 0.035 13.5 6.3 0.12 11.8 2.4 2.7 1 1 1 3 3 3 0 Domain of unknown function (DUF4618) BLOC1_2 PF10046.9 EKX47733.1 - 0.09 13.1 1.7 1.4 9.3 0.1 2.7 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BST2 PF16716.5 EKX47733.1 - 2.8 8.6 8.0 3.2 8.4 0.9 3.0 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 DUF3456 PF11938.8 EKX47734.1 - 0.0019 18.8 4.0 0.0093 16.5 1.7 2.8 1 1 1 2 2 2 1 TLR4 regulator and MIR-interacting MSAP PALP PF00291.25 EKX47735.1 - 6.9e-61 206.2 0.0 8.5e-61 205.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rad10 PF03834.14 EKX47737.1 - 2.4e-43 146.8 0.4 7.3e-43 145.2 0.1 1.9 2 1 0 2 2 2 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 EKX47737.1 - 1.9e-06 28.4 0.0 1.1e-05 25.9 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.23 EKX47737.1 - 7.7e-05 22.4 0.0 0.00024 20.8 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_3 PF12836.7 EKX47737.1 - 0.021 15.0 0.0 0.46 10.8 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH_2 PF12826.7 EKX47737.1 - 0.025 14.7 0.0 0.055 13.6 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Alpha_kinase PF02816.18 EKX47738.1 - 1.3e-06 28.7 0.0 0.028 14.5 0.0 3.2 2 2 0 2 2 2 2 Alpha-kinase family CH PF00307.31 EKX47739.1 - 1.7e-12 47.5 1.4 0.00029 21.0 0.0 4.9 4 1 0 5 5 5 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EKX47739.1 - 0.0039 17.0 0.1 0.4 10.5 0.0 3.1 3 0 0 3 3 3 1 CAMSAP CH domain ABC_membrane_2 PF06472.15 EKX47740.1 - 1.4e-49 168.9 6.8 1.9e-49 168.5 6.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EKX47740.1 - 7.3e-16 58.9 0.0 7.5e-15 55.7 0.0 2.2 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 EKX47740.1 - 0.00057 19.6 9.4 0.001 18.8 9.4 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.6 EKX47740.1 - 0.00063 20.2 0.0 0.0014 19.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EKX47740.1 - 0.0033 17.4 0.0 0.0081 16.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 EKX47740.1 - 0.006 16.3 0.0 0.019 14.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EKX47740.1 - 0.029 14.6 0.3 0.23 11.7 0.0 2.4 3 0 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 EKX47740.1 - 0.067 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 EKX47740.1 - 0.069 13.1 0.0 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase Sigma54_activat PF00158.26 EKX47740.1 - 0.099 12.3 0.1 5.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_21 PF13304.6 EKX47740.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system PduV-EutP PF10662.9 EKX47740.1 - 0.13 12.0 0.3 4.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 EKX47740.1 - 0.18 11.8 0.2 0.62 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) WD40 PF00400.32 EKX47741.1 - 3e-07 31.0 6.0 0.0043 17.9 0.4 5.5 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX47741.1 - 0.0019 18.4 0.1 0.65 10.3 0.0 4.1 5 1 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Vps36-NZF-N PF16988.5 EKX47741.1 - 0.17 11.3 0.7 13 5.3 0.0 2.7 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain RRM_1 PF00076.22 EKX47742.1 - 4.9e-10 39.1 0.0 8.9e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_1 PF00036.32 EKX47743.1 - 5.7e-14 50.5 2.0 1.2e-07 30.8 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX47743.1 - 7e-13 48.8 0.3 7.6e-13 48.7 0.3 1.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX47743.1 - 1.7e-12 46.2 2.7 4.8e-09 35.4 0.1 2.5 2 1 1 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 EKX47743.1 - 5.4e-12 45.4 5.1 2.4e-10 40.1 0.6 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX47743.1 - 5.2e-06 25.7 2.0 8.7e-05 21.8 0.2 2.3 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 EKX47743.1 - 5.5e-06 26.6 0.0 6.1e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.7 EKX47743.1 - 0.16 12.0 0.2 5.5 7.0 0.0 2.0 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand PhzC-PhzF PF02567.16 EKX47744.1 - 2.4e-16 60.1 0.0 3.2e-15 56.4 0.0 2.1 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein RelA_SpoT PF04607.17 EKX47745.1 - 5.2e-23 81.5 0.0 7.9e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins HD_4 PF13328.6 EKX47745.1 - 6.5e-17 61.7 0.0 1.3e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 HD domain Pkinase PF00069.25 EKX47746.1 - 9.2e-53 179.3 0.0 1e-52 179.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX47746.1 - 1.2e-32 113.2 0.0 1.3e-32 113.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX47746.1 - 0.0014 18.1 0.0 0.0041 16.5 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EKX47746.1 - 0.0044 17.0 2.2 0.013 15.4 0.7 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX47746.1 - 0.1 11.4 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase MORN PF02493.20 EKX47747.1 - 4.8e-21 73.3 22.0 2e-06 27.4 0.8 5.1 5 0 0 5 5 5 5 MORN repeat MA3 PF02847.17 EKX47748.1 - 6.8e-27 93.7 1.2 2.7e-26 91.7 0.9 2.2 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 EKX47748.1 - 3.5e-13 49.7 0.2 1.4e-12 47.8 0.2 2.1 1 0 0 1 1 1 1 MIF4G domain YBD PF17725.1 EKX47748.1 - 0.066 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 YAP binding domain TLP-20 PF06088.11 EKX47748.1 - 0.34 10.8 9.4 0.18 11.7 0.6 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FAM176 PF14851.6 EKX47748.1 - 0.34 10.6 12.4 6.1 6.5 9.2 2.4 2 0 0 2 2 2 0 FAM176 family DUF5523 PF17661.1 EKX47748.1 - 0.42 10.3 17.8 0.021 14.5 12.2 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5523) PAP1 PF08601.10 EKX47748.1 - 7.1 6.2 19.3 16 5.1 19.3 1.5 1 0 0 1 1 1 0 Transcription factor PAP1 RDD PF06271.12 EKX47749.1 - 0.0039 17.4 7.0 0.012 15.8 7.0 1.9 1 1 0 1 1 1 1 RDD family Cue1_U7BR PF18499.1 EKX47750.1 - 0.73 9.9 5.0 2.4 8.3 5.0 1.8 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 Pkinase PF00069.25 EKX47751.1 - 1.2e-67 228.0 0.0 1.9e-67 227.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX47751.1 - 4.1e-33 114.7 0.0 5.4e-22 78.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EKX47751.1 - 4.1e-08 32.9 0.0 0.11 11.7 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 EKX47751.1 - 0.014 14.2 0.5 0.038 12.8 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 EKX47751.1 - 0.07 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EKX47751.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Inhibitor_Mig-6 PF11555.8 EKX47751.1 - 0.17 12.0 0.9 0.5 10.5 0.0 2.3 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 pPIWI_RE_Y PF18156.1 EKX47752.1 - 0.074 13.5 0.0 0.095 13.1 0.0 1.2 1 0 0 1 1 1 0 pPIWI_RE three-gene island domain Y G10 PF01125.17 EKX47753.1 - 1.4e-49 167.6 0.2 1.8e-49 167.3 0.2 1.1 1 0 0 1 1 1 1 G10 protein HIT PF01230.23 EKX47754.1 - 1.8e-27 95.9 0.0 2.4e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EKX47754.1 - 1.1e-11 45.2 0.0 1.5e-11 44.8 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Phycoerythr_ab PF02972.14 EKX47755.1 - 3.5e-24 84.4 0.0 7.1e-24 83.4 0.0 1.5 1 0 0 1 1 1 1 Phycoerythrin, alpha/beta chain Solute_trans_a PF03619.16 EKX47756.1 - 1.1e-66 225.1 14.1 1.4e-66 224.8 14.1 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Caveolin PF01146.17 EKX47756.1 - 2.9 7.9 10.2 0.058 13.4 2.0 2.2 2 1 0 2 2 2 0 Caveolin Ank_5 PF13857.6 EKX47757.1 - 4.2e-13 49.2 0.1 1.9e-06 28.0 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX47757.1 - 6.9e-12 45.3 0.0 3.6e-05 24.0 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EKX47757.1 - 7e-11 42.4 0.0 2.5e-05 24.7 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX47757.1 - 1.3e-10 41.7 0.0 1.6e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX47757.1 - 3.3e-08 33.2 0.0 0.034 14.7 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat HPIP_like PF18524.1 EKX47758.1 - 0.055 13.2 0.1 0.084 12.7 0.1 1.3 1 0 0 1 1 1 0 High potential iron-sulfur protein like PKD_channel PF08016.12 EKX47759.1 - 2.8e-45 154.8 7.9 3.4e-45 154.5 7.9 1.0 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 EKX47759.1 - 0.00023 20.5 16.7 0.00034 19.9 16.7 1.2 1 0 0 1 1 1 1 Ion transport protein CENP-H PF05837.12 EKX47760.1 - 0.45 10.9 36.9 0.056 13.8 2.5 4.5 4 1 0 4 4 4 0 Centromere protein H (CENP-H) PNKP_ligase PF16542.5 EKX47760.1 - 1.4 8.4 7.1 0.098 12.1 1.1 2.1 3 0 0 3 3 3 0 PNKP adenylyltransferase domain, ligase domain PspA_IM30 PF04012.12 EKX47760.1 - 1.6 8.3 38.1 0.24 11.0 2.4 4.3 3 1 0 3 3 3 0 PspA/IM30 family DUF4250 PF14056.6 EKX47760.1 - 5.2 7.1 6.1 2.4 8.2 0.2 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4250) Lebercilin PF15619.6 EKX47760.1 - 5.3 6.6 44.7 0.046 13.4 2.8 3.6 3 1 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease V_ATPase_I PF01496.19 EKX47760.1 - 7.8 4.3 20.8 0.28 9.0 11.1 2.7 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family Bacillus_HBL PF05791.11 EKX47760.1 - 8.3 6.2 10.1 1.5 8.6 1.5 2.8 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) NPV_P10 PF05531.12 EKX47760.1 - 8.8 6.9 6.5 7.5 7.1 0.1 4.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 EKX47760.1 - 9.5 5.0 46.5 0.1 11.5 22.9 3.5 3 1 0 3 3 3 0 Spc7 kinetochore protein UPF0220 PF05255.11 EKX47761.1 - 1e-14 54.4 3.2 1.2e-13 50.9 3.2 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0220) HisKA_7TM PF16927.5 EKX47761.1 - 0.032 14.3 1.9 0.072 13.1 0.4 1.9 2 0 0 2 2 2 0 N-terminal 7TM region of histidine kinase Phage_holin_5_2 PF16079.5 EKX47761.1 - 5.3 7.4 6.5 26 5.2 3.8 2.7 2 1 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V WD40 PF00400.32 EKX47762.1 - 4.7e-16 58.9 9.0 0.00036 21.3 0.0 7.0 7 1 0 7 7 7 4 WD domain, G-beta repeat Ank_2 PF12796.7 EKX47762.1 - 8.8e-14 51.9 0.3 1.5e-12 47.9 0.1 2.7 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX47762.1 - 1.9e-12 47.5 0.1 1.9e-05 25.1 0.0 3.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX47762.1 - 1.1e-10 40.8 1.3 0.015 15.8 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EKX47762.1 - 1.4e-07 31.6 3.0 0.042 14.3 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EKX47762.1 - 4.4e-07 30.1 0.2 8.4e-05 22.8 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Nup160 PF11715.8 EKX47762.1 - 5.3e-06 25.4 0.1 0.24 10.0 0.0 3.9 1 1 3 4 4 4 3 Nucleoporin Nup120/160 PQQ_2 PF13360.6 EKX47762.1 - 1.3e-05 24.9 0.2 0.00051 19.7 0.1 2.8 1 1 2 3 3 3 2 PQQ-like domain PQQ_3 PF13570.6 EKX47762.1 - 0.003 18.0 7.3 0.89 10.1 0.1 5.0 4 1 0 4 4 4 1 PQQ-like domain PQQ PF01011.21 EKX47762.1 - 1 9.4 3.4 6.1 7.0 0.1 3.5 4 0 0 4 4 4 0 PQQ enzyme repeat ATG7_N PF16420.5 EKX47763.1 - 2.1e-68 231.2 0.0 2.7e-68 230.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 EKX47763.1 - 8.5e-41 139.9 0.0 1.4e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 EKX47763.1 - 0.0025 17.9 0.0 0.085 12.9 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EKX47763.1 - 0.004 16.5 0.0 0.024 14.0 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MT-A70 PF05063.14 EKX47763.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 MT-A70 RNA_pol_Rbc25 PF08292.12 EKX47764.1 - 1.2e-25 90.2 1.4 4.7e-18 65.7 0.1 2.5 2 1 0 3 3 3 2 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 EKX47764.1 - 5.2e-12 46.0 0.1 9.5e-12 45.1 0.0 1.5 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EKX47764.1 - 0.0041 17.4 0.0 0.012 16.0 0.0 1.7 2 0 0 2 2 2 1 S1 RNA binding domain S1_2 PF13509.6 EKX47764.1 - 0.013 15.5 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 S1 domain DUF1453 PF07301.11 EKX47764.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1453) DivIC PF04977.15 EKX47765.1 - 0.031 14.0 1.0 0.031 14.0 1.0 5.0 4 1 1 5 5 5 0 Septum formation initiator CENP-F_leu_zip PF10473.9 EKX47765.1 - 0.11 12.5 46.1 0.086 12.9 15.0 3.6 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Exonuc_VII_L PF02601.15 EKX47765.1 - 0.16 11.5 24.0 0.21 11.1 7.3 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit LPP PF04728.13 EKX47765.1 - 3.7 8.0 8.5 13 6.3 0.1 4.1 3 0 0 3 3 3 0 Lipoprotein leucine-zipper His_Phos_1 PF00300.22 EKX47766.1 - 1.8e-36 125.7 0.0 3.1e-32 111.8 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Collagen PF01391.18 EKX47767.1 - 1.1e-07 31.5 23.3 3e-07 30.1 23.3 1.7 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) LAG1-DNAbind PF09271.11 EKX47768.1 - 0.05 14.2 2.1 0.059 14.0 0.9 1.7 1 1 1 2 2 2 0 LAG1, DNA binding She9_MDM33 PF05546.11 EKX47768.1 - 0.093 12.5 7.9 0.12 12.1 0.2 2.7 3 0 0 3 3 3 0 She9 / Mdm33 family FPV060 PF17614.2 EKX47768.1 - 0.63 9.4 2.3 1 8.7 0.2 2.2 3 0 0 3 3 3 0 Viral CC-type chemokine DUF4140 PF13600.6 EKX47768.1 - 0.7 10.4 3.4 4.7 7.7 0.2 2.5 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Peptidase_M14 PF00246.24 EKX47769.1 - 4.9e-17 62.7 0.0 1.1e-16 61.6 0.0 1.5 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 EKX47769.1 - 8.8e-13 48.6 0.1 1.8e-12 47.5 0.1 1.5 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 EKX47769.1 - 0.14 11.2 0.1 0.18 10.8 0.1 1.2 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Collagen PF01391.18 EKX47770.1 - 6.3e-19 67.5 61.1 2.7e-10 39.8 27.6 2.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) HOOK PF05622.12 EKX47771.1 - 4.7e-27 94.5 4.3 4.7e-27 94.5 4.3 3.2 1 1 1 2 2 2 1 HOOK protein Pkinase PF00069.25 EKX47771.1 - 7.1e-24 84.6 0.0 2.5e-22 79.5 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX47771.1 - 3.9e-16 59.1 0.0 3.8e-15 55.9 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase CH PF00307.31 EKX47771.1 - 0.0027 17.9 0.1 0.0092 16.2 0.1 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain TSC22 PF01166.18 EKX47771.1 - 0.62 10.4 6.1 0.29 11.5 0.5 3.5 3 1 0 3 3 3 0 TSC-22/dip/bun family DUF3500 PF12006.8 EKX47771.1 - 5.9 6.3 7.8 0.17 11.3 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3500) ER_lumen_recept PF00810.18 EKX47773.1 - 1.6e-09 38.7 0.5 2.9e-09 37.9 0.5 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF1211 PF06736.11 EKX47773.1 - 0.027 14.9 0.5 0.087 13.3 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1211) SET PF00856.28 EKX47774.1 - 5.5e-10 39.9 0.2 2.7e-08 34.4 0.2 2.2 1 1 0 1 1 1 1 SET domain Kelch_1 PF01344.25 EKX47777.1 - 4.6e-44 147.8 4.8 1.3e-07 31.0 0.0 6.6 6 1 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 EKX47777.1 - 3.9e-31 106.3 0.0 0.00012 22.2 0.0 6.0 3 1 3 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EKX47777.1 - 2e-22 78.2 0.7 6.3e-05 22.8 0.0 6.2 6 0 0 6 6 6 5 Kelch motif BACK PF07707.15 EKX47777.1 - 1.7e-17 63.4 0.1 3.6e-16 59.1 0.0 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch Kelch_4 PF13418.6 EKX47777.1 - 5.7e-12 45.4 0.1 0.063 13.3 0.0 5.7 4 1 1 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 EKX47777.1 - 8.6e-11 41.8 0.1 0.0017 18.6 0.0 4.8 5 1 1 6 6 6 3 Galactose oxidase, central domain BTB PF00651.31 EKX47777.1 - 2.2e-07 31.1 0.1 6.4e-07 29.6 0.1 1.8 2 0 0 2 2 2 1 BTB/POZ domain Kelch_5 PF13854.6 EKX47777.1 - 6.4e-06 26.0 0.6 2.2 8.3 0.0 4.9 5 0 0 5 5 5 1 Kelch motif Chloroa_b-bind PF00504.21 EKX47778.1 - 7.4e-40 137.1 0.4 9.6e-40 136.7 0.4 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein BT1 PF03092.16 EKX47779.1 - 2.5e-61 207.5 15.2 4e-31 107.9 6.1 3.9 1 1 1 2 2 2 2 BT1 family G-patch PF01585.23 EKX47780.1 - 4.9e-13 48.7 3.3 1.1e-12 47.6 3.3 1.6 1 0 0 1 1 1 1 G-patch domain FHA PF00498.26 EKX47780.1 - 6.8e-12 45.6 0.0 1.4e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain G-patch_2 PF12656.7 EKX47780.1 - 7.9e-05 22.7 1.2 0.00023 21.2 1.2 1.8 1 0 0 1 1 1 1 G-patch domain Yop-YscD_cpl PF16697.5 EKX47780.1 - 0.00024 21.3 0.0 0.0014 18.9 0.0 2.3 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain DEAD PF00270.29 EKX47781.1 - 4.6e-15 55.8 0.0 9.8e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EKX47781.1 - 7.9e-09 35.7 0.0 3.6e-08 33.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EKX47781.1 - 3.6e-08 33.7 0.1 1.2e-07 32.0 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Phage_term_sma PF07141.11 EKX47781.1 - 0.0097 15.7 1.6 0.02 14.7 1.6 1.4 1 0 0 1 1 1 1 Putative bacteriophage terminase small subunit Na_Ca_ex_C PF16494.5 EKX47783.1 - 0.16 12.4 4.1 0.29 11.6 4.1 1.4 1 0 0 1 1 1 0 C-terminal extension of sodium/calcium exchanger domain zf-RING_2 PF13639.6 EKX47783.1 - 0.16 12.3 6.3 0.44 10.9 6.3 1.8 1 1 0 1 1 1 0 Ring finger domain Fcf1 PF04900.12 EKX47783.1 - 0.19 12.1 0.3 0.19 12.1 0.3 2.0 2 0 0 2 2 2 0 Fcf1 KIP1 PF07765.12 EKX47783.1 - 0.23 11.6 4.0 0.29 11.3 2.6 1.9 1 1 0 1 1 1 0 KIP1-like protein zinc_ribbon_5 PF13719.6 EKX47783.1 - 4.9 7.0 8.0 0.27 11.0 1.8 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_5 PF14634.6 EKX47783.1 - 9 6.3 9.1 23 5.1 9.1 1.7 1 1 0 1 1 1 0 zinc-RING finger domain Ion_trans PF00520.31 EKX47784.1 - 3.1e-22 79.0 12.1 4.8e-22 78.4 12.1 1.2 1 0 0 1 1 1 1 Ion transport protein C2 PF00168.30 EKX47784.1 - 2.4e-18 66.3 0.0 3.8e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain Ion_trans_2 PF07885.16 EKX47784.1 - 8.6e-10 38.4 6.6 2.3e-09 37.1 6.6 1.8 1 0 0 1 1 1 1 Ion channel cNMP_binding PF00027.29 EKX47784.1 - 2.6e-09 37.0 0.0 1.9e-08 34.3 0.0 2.2 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain DUF3437 PF11919.8 EKX47785.1 - 6.4e-32 109.3 0.0 1.3e-31 108.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.22 EKX47785.1 - 7.5e-05 22.7 0.2 0.021 15.1 0.1 3.1 2 0 0 2 2 2 1 HEAT repeat HEAT_EZ PF13513.6 EKX47785.1 - 0.0013 19.1 0.1 0.054 14.0 0.0 2.7 3 0 0 3 3 3 1 HEAT-like repeat CLASP_N PF12348.8 EKX47785.1 - 0.015 14.8 0.1 0.087 12.4 0.0 1.9 2 0 0 2 2 2 0 CLASP N terminal Laminin_G_3 PF13385.6 EKX47786.1 - 3.2e-15 56.6 0.0 1.6e-13 51.1 0.0 2.5 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Ephrin_rec_like PF07699.13 EKX47786.1 - 4.1e-13 48.8 42.7 3.8e-06 26.6 9.7 5.4 3 1 2 5 5 5 3 Putative ephrin-receptor like Pentaxin PF00354.17 EKX47786.1 - 0.004 16.9 0.0 0.0075 16.0 0.0 1.3 1 0 0 1 1 1 1 Pentaxin family Laminin_G_2 PF02210.24 EKX47786.1 - 0.0055 17.3 0.0 0.012 16.2 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain Lact-deh-memb PF09330.11 EKX47787.1 - 0.044 13.1 0.1 0.053 12.9 0.1 1.2 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding FapA PF03961.13 EKX47787.1 - 0.36 9.4 8.0 0.38 9.3 8.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4094 PF13334.6 EKX47787.1 - 1 9.8 6.0 2.9 8.4 5.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) SE PF08491.10 EKX47788.1 - 0.088 11.8 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase adh_short PF00106.25 EKX47789.1 - 7.5e-05 22.3 0.0 7.5e-05 22.3 0.0 3.0 2 1 2 4 4 4 1 short chain dehydrogenase TFIIA PF03153.13 EKX47789.1 - 2.7 7.9 19.6 4.4 7.2 19.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_34 PF13872.6 EKX47790.1 - 6.6e-116 386.4 0.0 9.7e-116 385.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 EKX47790.1 - 4.1e-87 292.3 0.4 2.4e-86 289.8 0.4 2.0 1 1 0 1 1 1 1 C-terminal domain on Strawberry notch homologue Helicase_C PF00271.31 EKX47790.1 - 0.00098 19.4 0.1 0.0025 18.2 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Phage_tail_NK PF16532.5 EKX47790.1 - 0.0078 15.9 0.0 1.9 8.1 0.0 2.4 2 0 0 2 2 2 2 Sf6-type phage tail needle knob or tip of some Caudovirales OTU PF02338.19 EKX47790.1 - 0.031 14.8 0.0 0.07 13.6 0.0 1.5 1 0 0 1 1 1 0 OTU-like cysteine protease ResIII PF04851.15 EKX47790.1 - 0.038 14.0 0.0 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Zot PF05707.12 EKX47790.1 - 0.12 12.1 0.1 2.2 7.9 0.0 2.5 2 1 1 3 3 3 0 Zonular occludens toxin (Zot) AIM24 PF01987.17 EKX47792.1 - 1.7e-34 119.4 0.0 2.2e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 RWP-RK PF02042.15 EKX47794.1 - 1.3e-16 60.3 0.1 9.6e-16 57.5 0.1 2.2 2 0 0 2 2 2 1 RWP-RK domain ABC2_membrane PF01061.24 EKX47795.1 - 1.2e-35 122.9 0.7 1.5e-35 122.5 0.7 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EKX47795.1 - 1.2e-22 80.9 0.1 2.5e-22 79.9 0.1 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EKX47795.1 - 1.9e-07 31.2 0.1 0.0062 16.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EKX47795.1 - 1e-05 26.0 0.1 3.3e-05 24.3 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EKX47795.1 - 6.4e-05 22.5 0.1 0.00035 20.1 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EKX47795.1 - 0.00058 19.6 0.4 0.0014 18.3 0.4 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain NTPase_1 PF03266.15 EKX47795.1 - 0.00068 19.6 0.1 0.023 14.6 0.1 2.3 2 0 0 2 2 2 1 NTPase RsgA_GTPase PF03193.16 EKX47795.1 - 0.00088 19.2 0.2 0.0018 18.2 0.2 1.5 1 0 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 EKX47795.1 - 0.0011 18.2 0.0 0.0018 17.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.6 EKX47795.1 - 0.0013 19.3 0.1 0.0032 18.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EKX47795.1 - 0.0013 19.2 0.1 0.0058 17.2 0.0 2.1 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 EKX47795.1 - 0.0029 17.9 0.0 0.0078 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EKX47795.1 - 0.0047 16.7 0.2 0.0091 15.7 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EKX47795.1 - 0.014 15.8 0.0 0.039 14.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EKX47795.1 - 0.019 15.4 0.2 0.076 13.4 0.2 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EKX47795.1 - 0.02 14.9 0.0 0.06 13.4 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 EKX47795.1 - 0.022 14.7 0.2 0.055 13.4 0.2 1.7 2 0 0 2 2 1 0 NACHT domain Rad17 PF03215.15 EKX47795.1 - 0.028 14.3 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain cobW PF02492.19 EKX47795.1 - 0.03 13.9 0.1 0.062 12.9 0.1 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 EKX47795.1 - 0.035 13.9 0.1 0.079 12.7 0.1 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 EKX47795.1 - 0.036 13.8 0.2 0.29 10.8 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EKX47795.1 - 0.054 13.5 0.1 0.22 11.5 0.1 2.1 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EKX47795.1 - 0.07 13.2 0.0 0.44 10.6 0.0 2.2 2 0 0 2 2 2 0 Dynamin family MobB PF03205.14 EKX47795.1 - 0.091 12.7 0.1 0.21 11.5 0.0 1.8 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.6 EKX47795.1 - 0.12 12.0 0.0 0.41 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EKX47795.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EKX47795.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.6 EKX47795.1 - 0.14 12.4 0.2 0.33 11.2 0.2 1.6 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.7 EKX47795.1 - 0.24 10.4 6.3 0.29 10.2 5.2 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein WD40 PF00400.32 EKX47796.1 - 1.5e-48 161.7 8.8 6.5e-09 36.3 0.2 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX47796.1 - 5.7e-16 58.6 0.3 0.027 14.8 0.0 5.2 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EKX47796.1 - 1.2e-06 28.6 0.0 0.014 15.3 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EKX47796.1 - 1.7e-06 27.3 0.1 0.19 10.6 0.0 3.8 1 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 EKX47796.1 - 3.1e-05 22.2 0.2 0.0004 18.5 0.1 2.2 1 1 0 2 2 2 1 IKI3 family PD40 PF07676.12 EKX47796.1 - 0.002 18.0 2.2 3.2 7.8 0.1 4.1 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Frtz PF11768.8 EKX47796.1 - 0.023 13.0 0.0 0.4 8.9 0.0 2.1 1 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 EKX47796.1 - 0.031 13.6 0.0 0.23 10.7 0.0 2.2 2 1 1 3 3 3 0 WD40-like domain Proteasome_A_N PF10584.9 EKX47796.1 - 0.09 12.5 2.4 28 4.5 0.0 4.2 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Str_synth PF03088.16 EKX47796.1 - 0.13 12.4 0.0 21 5.3 0.0 2.4 2 0 0 2 2 2 0 Strictosidine synthase Collagen PF01391.18 EKX47797.1 - 2.6e-08 33.5 21.3 4.3e-08 32.8 21.3 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) DUF3382 PF11862.8 EKX47797.1 - 0.1 12.9 0.1 0.14 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) TRAP_beta PF05753.14 EKX47798.1 - 7.7e-37 126.4 0.0 9.2e-37 126.1 0.0 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) CARDB PF07705.11 EKX47798.1 - 0.015 15.5 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 CARDB IP_trans PF02121.18 EKX47799.1 - 1.1e-84 283.9 2.7 1.6e-84 283.3 2.7 1.2 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein WW PF00397.26 EKX47799.1 - 1.2e-11 44.5 0.3 3.3e-11 43.1 0.1 1.9 2 0 0 2 2 2 1 WW domain Rer1 PF03248.13 EKX47800.1 - 5.4e-65 218.3 5.0 6.6e-65 218.0 5.0 1.0 1 0 0 1 1 1 1 Rer1 family Ac110_PIF PF07280.11 EKX47800.1 - 0.14 12.0 0.3 0.14 12.0 0.3 2.2 3 0 0 3 3 3 0 Per os infectivity factor AC110 DUF4131 PF13567.6 EKX47800.1 - 1.6 8.4 3.9 8.9 5.9 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2244 PF10003.9 EKX47800.1 - 4 7.1 5.8 8.1 6.1 2.4 2.0 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Acid_PPase PF12689.7 EKX47802.1 - 5.8e-28 97.9 0.0 9.3e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.6 EKX47802.1 - 0.00071 19.7 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase TraV PF09676.10 EKX47802.1 - 1.4 9.9 5.0 2.3 9.2 5.0 1.3 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) MAJIN PF15077.6 EKX47802.1 - 2.1 8.1 6.4 3.1 7.5 6.4 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein TFA2_Winged_2 PF18121.1 EKX47803.1 - 0.0025 17.5 0.0 0.0066 16.1 0.0 1.7 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 SPT16 PF08644.11 EKX47803.1 - 0.81 9.9 4.1 1.8 8.8 4.1 1.5 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) AAA_12 PF13087.6 EKX47804.1 - 1.2e-20 74.0 0.5 1.2e-20 74.0 0.5 1.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EKX47804.1 - 7.1e-05 22.6 0.0 9.6e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain CPSase_L_D2 PF02786.17 EKX47805.1 - 3.1e-78 262.1 0.1 4.9e-78 261.4 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EKX47805.1 - 4.8e-45 152.6 0.4 1.8e-43 147.6 0.1 2.6 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EKX47805.1 - 2.7e-34 117.5 0.0 1.1e-33 115.5 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EKX47805.1 - 4.3e-16 58.5 0.2 4.3e-16 58.5 0.2 2.7 3 0 0 3 3 3 1 Biotin-requiring enzyme ATP-grasp PF02222.22 EKX47805.1 - 4.6e-08 32.8 0.0 1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EKX47805.1 - 1e-07 31.7 0.0 3.1e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus PCC_BT PF18140.1 EKX47805.1 - 2e-07 31.4 0.2 1.1e-06 28.9 0.1 2.3 2 1 0 2 2 2 1 Propionyl-coenzyme A carboxylase BT domain ATPgrasp_ST PF14397.6 EKX47805.1 - 0.00028 20.3 0.1 0.055 12.7 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp RimK PF08443.11 EKX47805.1 - 0.0016 18.0 0.0 0.017 14.7 0.0 2.3 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 EKX47805.1 - 0.022 14.8 0.0 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 EKX47805.1 - 0.026 14.4 0.0 0.099 12.5 0.0 2.0 1 1 1 2 2 2 0 Biotin-lipoyl like LAL_C2 PF18603.1 EKX47805.1 - 0.032 14.4 0.0 0.13 12.5 0.0 2.1 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 RnfC_N PF13375.6 EKX47805.1 - 0.062 13.3 0.1 0.27 11.2 0.1 2.1 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Ribosomal_L24e PF01246.20 EKX47807.1 - 0.036 14.3 0.0 0.058 13.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L24e Zn_clus PF00172.18 EKX47808.1 - 3e-08 33.7 13.7 3e-08 33.7 13.7 3.0 1 1 1 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_methylase PF00145.17 EKX47809.1 - 5.2e-36 124.7 0.0 1.3e-35 123.3 0.0 1.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase PP2C PF00481.21 EKX47810.1 - 1.3e-54 185.5 0.0 3.6e-53 180.8 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EKX47810.1 - 0.094 12.3 0.3 0.22 11.1 0.3 1.6 1 1 0 1 1 1 0 Protein phosphatase 2C Zn-C2H2_12 PF18112.1 EKX47811.1 - 0.017 15.6 0.2 0.038 14.5 0.2 1.6 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_4 PF13894.6 EKX47811.1 - 0.059 14.2 2.0 4.8 8.3 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger PIP5K PF01504.18 EKX47812.1 - 2.4e-40 138.5 0.0 1.2e-38 133.0 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF4355 PF14265.6 EKX47812.1 - 0.0052 17.0 0.2 0.0099 16.1 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4355) TTL PF03133.15 EKX47813.1 - 2.6e-87 292.7 3.0 3.5e-87 292.2 3.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EKX47813.1 - 8.7e-09 35.0 0.6 0.00018 20.8 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EKX47813.1 - 8.1e-05 22.0 0.1 0.034 13.4 0.1 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp PA14 PF07691.12 EKX47814.1 - 0.00015 21.6 0.3 0.0022 17.8 0.0 2.4 2 0 0 2 2 2 1 PA14 domain GLEYA PF10528.9 EKX47814.1 - 0.00086 19.7 0.1 0.18 12.3 0.1 2.6 2 0 0 2 2 2 2 GLEYA domain Wzt_C PF14524.6 EKX47814.1 - 0.11 12.6 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Wzt C-terminal domain DUF148 PF02520.17 EKX47815.1 - 0.037 14.2 4.3 0.075 13.1 3.8 1.8 1 1 0 1 1 1 0 Domain of unknown function DUF148 hGDE_central PF14702.6 EKX47815.1 - 0.3 10.7 4.8 0.22 11.2 3.2 1.6 1 1 0 1 1 1 0 Central domain of human glycogen debranching enzyme DUF1515 PF07439.11 EKX47815.1 - 7.9 6.6 6.1 2.3 8.3 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Suf PF05843.14 EKX47816.1 - 8.9e-61 206.4 6.7 2.1e-58 198.7 1.3 2.6 2 1 0 2 2 2 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EKX47816.1 - 2.4e-08 34.1 0.3 0.042 14.7 0.0 6.4 6 2 3 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX47816.1 - 1.9e-05 24.7 0.3 0.021 15.2 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX47816.1 - 4.1e-05 24.0 0.2 0.16 12.5 0.0 4.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX47816.1 - 0.0002 21.2 5.5 0.029 14.5 0.0 5.3 7 0 0 7 7 7 1 Tetratricopeptide repeat NRDE-2 PF08424.10 EKX47816.1 - 0.0013 18.0 8.4 0.037 13.1 0.9 3.7 2 1 2 4 4 4 3 NRDE-2, necessary for RNA interference TPR_15 PF13429.6 EKX47816.1 - 0.0015 17.8 0.5 0.19 10.9 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX47816.1 - 0.01 16.0 1.3 22 5.6 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EKX47816.1 - 0.048 13.3 0.0 14 5.4 0.0 3.9 3 0 0 3 3 3 0 TPR repeat TPR_16 PF13432.6 EKX47816.1 - 0.049 14.3 0.2 8.6 7.1 0.0 3.8 4 1 0 4 4 4 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EKX47816.1 - 0.35 10.8 11.9 30 4.6 0.9 5.9 6 1 0 6 6 6 0 Mad3/BUB1 homology region 1 Ank_5 PF13857.6 EKX47817.1 - 9.2e-13 48.1 0.1 2.8e-09 37.0 0.1 2.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX47817.1 - 9.9e-13 48.5 0.1 1.5e-12 47.9 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX47817.1 - 4.2e-11 43.2 0.2 1.4e-10 41.5 0.2 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX47817.1 - 2.2e-09 37.3 0.4 0.00023 21.5 0.3 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EKX47817.1 - 2.7e-09 36.5 0.4 0.00081 19.7 0.2 2.5 2 0 0 2 2 2 2 Ankyrin repeat XPB_DRD PF18458.1 EKX47817.1 - 0.087 12.7 0.5 4.6 7.2 0.2 2.4 2 0 0 2 2 2 0 Xeroderma pigmentosum group B helicase damage recognition domain AIRC PF00731.20 EKX47818.1 - 0.13 11.9 2.3 0.26 10.9 2.3 1.5 1 0 0 1 1 1 0 AIR carboxylase Laminin_B PF00052.18 EKX47819.1 - 6.1e-05 22.9 0.0 0.00034 20.5 0.0 2.2 2 0 0 2 2 2 1 Laminin B (Domain IV) ER PF01133.17 EKX47819.1 - 0.032 14.3 0.2 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Enhancer of rudimentary DUF4548 PF15081.6 EKX47819.1 - 0.12 12.2 0.6 0.23 11.3 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4548) Ndc1_Nup PF09531.10 EKX47819.1 - 0.36 9.5 4.5 0.48 9.0 4.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zip PF02535.22 EKX47819.1 - 1.3 8.1 3.6 2.2 7.4 3.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter EF-hand_1 PF00036.32 EKX47820.1 - 5.6e-16 56.8 0.1 2.7e-08 32.8 0.0 3.8 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 EKX47820.1 - 3.9e-15 55.4 0.2 1.8e-06 27.7 0.0 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.6 EKX47820.1 - 6.8e-15 55.3 0.0 1.6e-06 28.4 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX47820.1 - 4.2e-13 48.1 0.0 4.1e-07 29.4 0.1 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_9 PF14658.6 EKX47820.1 - 2.6e-09 37.2 0.0 6.4e-06 26.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EKX47820.1 - 6.8e-09 34.8 0.3 1.6e-07 30.5 0.0 2.8 3 0 0 3 3 3 1 EF hand TerB PF05099.13 EKX47820.1 - 0.00091 19.2 0.0 0.48 10.4 0.0 2.1 2 0 0 2 2 2 2 Tellurite resistance protein TerB EF-hand_11 PF08976.11 EKX47820.1 - 0.0081 17.0 0.0 0.019 15.8 0.0 1.5 1 1 0 1 1 1 1 EF-hand domain Retrotrans_gag PF03732.17 EKX47820.1 - 0.019 15.2 0.0 0.15 12.3 0.0 1.9 1 1 1 2 2 2 0 Retrotransposon gag protein UPF0154 PF03672.13 EKX47820.1 - 0.061 13.4 0.0 2.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) EF-hand_4 PF12763.7 EKX47820.1 - 0.16 11.9 0.0 2.8 7.9 0.0 2.2 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Prefoldin_3 PF13758.6 EKX47820.1 - 0.2 11.8 0.1 0.79 9.8 0.0 2.0 2 1 0 2 2 2 0 Prefoldin subunit Ank_2 PF12796.7 EKX47821.1 - 1.6e-34 118.4 5.4 6.9e-12 45.8 0.1 4.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX47821.1 - 7e-30 103.0 7.2 1.1e-12 48.2 0.1 6.4 3 3 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 EKX47821.1 - 9.8e-21 73.2 11.4 0.00049 20.4 0.1 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 EKX47821.1 - 1.6e-20 71.0 0.8 0.007 16.8 0.0 7.5 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EKX47821.1 - 4e-16 58.9 11.8 0.00011 22.4 0.1 6.2 4 3 3 7 7 7 6 Ankyrin repeats (many copies) CheR PF01739.18 EKX47821.1 - 0.088 12.3 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain TSC22 PF01166.18 EKX47822.1 - 0.0043 17.3 1.2 0.013 15.8 1.2 1.8 1 0 0 1 1 1 1 TSC-22/dip/bun family bZIP_2 PF07716.15 EKX47822.1 - 0.011 15.8 7.4 0.02 14.9 2.4 2.7 2 0 0 2 2 2 0 Basic region leucine zipper HALZ PF02183.18 EKX47822.1 - 0.011 15.9 1.1 0.023 14.9 0.9 1.7 1 1 1 2 2 2 0 Homeobox associated leucine zipper Leu_zip PF15294.6 EKX47822.1 - 0.022 14.3 9.5 0.077 12.5 9.6 1.7 1 1 0 1 1 1 0 Leucine zipper NUP50 PF08911.11 EKX47822.1 - 0.031 14.9 1.7 0.12 13.0 1.7 2.1 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) bZIP_1 PF00170.21 EKX47822.1 - 0.033 14.3 4.5 0.11 12.6 0.9 2.5 2 0 0 2 2 2 0 bZIP transcription factor YabA PF06156.13 EKX47822.1 - 0.038 14.6 3.1 0.038 14.6 3.1 1.8 1 1 0 1 1 1 0 Initiation control protein YabA Fez1 PF06818.15 EKX47822.1 - 0.059 13.8 14.4 0.086 13.3 14.4 1.2 1 0 0 1 1 1 0 Fez1 TUDOR PF00567.24 EKX47822.1 - 0.19 11.7 0.2 0.45 10.6 0.2 1.6 1 0 0 1 1 1 0 Tudor domain V_ATPase_I PF01496.19 EKX47822.1 - 0.62 7.9 5.1 0.82 7.5 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LPP PF04728.13 EKX47822.1 - 0.91 10.0 12.3 0.32 11.4 0.9 3.4 2 1 1 3 3 3 0 Lipoprotein leucine-zipper DivIC PF04977.15 EKX47822.1 - 3.4 7.5 9.1 0.45 10.3 2.1 2.4 2 0 0 2 2 2 0 Septum formation initiator Alanine_zipper PF11839.8 EKX47822.1 - 9.5 6.7 11.9 3.5 8.0 0.9 2.6 1 1 1 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein PDZ PF00595.24 EKX47823.1 - 1.4e-09 38.1 0.0 4.1e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX47823.1 - 3.8e-06 26.6 0.1 8.9e-06 25.5 0.1 1.6 1 0 0 1 1 1 1 PDZ domain DUF5037 PF16440.5 EKX47823.1 - 2.2 7.7 5.9 3.1 7.2 5.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5037) SPOC PF07744.13 EKX47824.1 - 5.8e-08 32.8 0.0 8.7e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 SPOC domain DUF1444 PF07285.11 EKX47825.1 - 0.1 12.1 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1444) MtN3_slv PF03083.16 EKX47826.1 - 4.5e-29 100.3 5.5 2.6e-18 65.9 2.1 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange PDZ PF00595.24 EKX47827.1 - 0.0033 17.8 0.0 0.0036 17.6 0.0 1.1 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX47827.1 - 0.009 15.8 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX47827.1 - 0.046 14.0 0.0 0.058 13.7 0.0 1.2 1 0 0 1 1 1 0 PDZ domain TFIIB PF00382.19 EKX47828.1 - 0.00037 20.5 0.1 0.0037 17.3 0.2 2.7 2 1 0 2 2 2 1 Transcription factor TFIIB repeat Prok-RING_1 PF14446.6 EKX47828.1 - 0.018 14.9 1.2 0.061 13.3 1.2 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PDZ_6 PF17820.1 EKX47828.1 - 0.044 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 EKX47828.1 - 0.049 14.0 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 PDZ domain ArfGap PF01412.18 EKX47828.1 - 0.077 13.1 0.4 0.15 12.2 0.4 1.4 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf PDZ_2 PF13180.6 EKX47828.1 - 0.19 12.1 0.0 0.82 10.0 0.0 2.0 2 0 0 2 2 2 0 PDZ domain TFIIB PF00382.19 EKX47830.1 - 0.00035 20.6 0.1 0.0036 17.3 0.2 2.7 2 1 0 2 2 2 1 Transcription factor TFIIB repeat Prok-RING_1 PF14446.6 EKX47830.1 - 0.024 14.6 1.1 0.079 12.9 1.1 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PDZ_6 PF17820.1 EKX47830.1 - 0.043 13.7 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 PDZ domain PDZ PF00595.24 EKX47830.1 - 0.045 14.1 0.0 0.098 13.0 0.0 1.5 1 0 0 1 1 1 0 PDZ domain ArfGap PF01412.18 EKX47830.1 - 0.093 12.8 0.4 0.17 11.9 0.4 1.3 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf PDZ_2 PF13180.6 EKX47830.1 - 0.17 12.2 0.0 0.8 10.1 0.0 2.1 2 0 0 2 2 2 0 PDZ domain Mito_carr PF00153.27 EKX47831.1 - 1.8e-57 191.3 2.3 3e-18 65.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EKX47831.1 - 0.00063 19.0 0.8 0.61 9.2 0.1 3.0 2 1 2 4 4 4 2 Gammaproteobacterial serine protease RelA_SpoT PF04607.17 EKX47832.1 - 0.12 12.7 0.1 0.33 11.2 0.0 1.7 2 0 0 2 2 2 0 Region found in RelA / SpoT proteins DUF4304 PF14137.6 EKX47833.1 - 0.13 12.5 0.1 0.39 10.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4304) TPR_2 PF07719.17 EKX47834.1 - 1.7e-30 102.7 25.8 8.9e-05 22.3 0.0 11.2 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_14 PF13428.6 EKX47834.1 - 1.1e-29 100.6 29.7 9.8e-05 22.9 0.0 9.9 3 3 7 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.6 EKX47834.1 - 1.1e-29 100.6 9.1 5.4e-05 23.3 0.0 8.6 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 EKX47834.1 - 4.1e-24 84.9 18.8 2.2e-08 34.5 0.6 6.5 3 1 2 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 EKX47834.1 - 1.1e-21 75.7 16.0 0.00021 21.0 0.0 9.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 EKX47834.1 - 8e-18 64.5 24.3 0.00044 20.5 0.1 8.0 6 3 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 EKX47834.1 - 3.5e-15 54.9 24.5 0.018 15.2 0.0 10.8 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX47834.1 - 3.6e-14 53.1 15.8 0.0056 17.3 0.1 7.0 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX47834.1 - 2.7e-12 46.2 9.6 0.0002 21.0 0.1 7.1 7 1 1 8 8 8 2 TPR repeat TPR_15 PF13429.6 EKX47834.1 - 2.1e-11 43.6 17.8 2.3e-05 23.8 0.5 5.2 1 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 EKX47834.1 - 1.6e-09 37.8 7.9 0.04 14.1 0.4 5.1 3 2 4 7 7 6 4 Tetratricopeptide repeat PDZ PF00595.24 EKX47834.1 - 1.8e-08 34.6 0.1 0.0033 17.7 0.0 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EKX47834.1 - 4.1e-07 29.7 0.0 0.0087 15.9 0.0 2.9 2 0 0 2 2 2 2 PDZ domain TPR_7 PF13176.6 EKX47834.1 - 4.3e-07 29.5 13.5 0.0085 16.1 0.0 7.6 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX47834.1 - 4e-06 27.1 24.3 0.55 11.0 0.0 10.2 12 0 0 12 12 10 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX47834.1 - 4.2e-06 26.5 27.8 0.095 12.6 0.3 8.1 9 0 0 9 9 8 3 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EKX47834.1 - 8.6e-06 25.7 10.5 0.093 12.7 0.1 6.3 6 1 0 6 6 6 1 Mad3/BUB1 homology region 1 TPR_MalT PF17874.1 EKX47834.1 - 1.7e-05 24.3 16.9 0.022 14.2 1.2 3.6 1 1 1 3 3 3 2 MalT-like TPR region PDZ_2 PF13180.6 EKX47834.1 - 2.5e-05 24.5 0.1 0.35 11.2 0.0 2.8 3 0 0 3 3 2 2 PDZ domain NARP1 PF12569.8 EKX47834.1 - 7.6e-05 21.8 0.2 0.3 9.9 0.0 3.5 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 DUF3808 PF10300.9 EKX47834.1 - 0.0088 14.8 0.8 2.4 6.8 0.2 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3808) PPR PF01535.20 EKX47834.1 - 0.013 15.7 9.1 37 4.9 0.0 7.1 8 0 0 8 8 5 0 PPR repeat ANAPC3 PF12895.7 EKX47834.1 - 0.015 15.5 3.9 0.73 10.1 0.1 3.5 1 1 4 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Wzy_C_2 PF11846.8 EKX47834.1 - 0.05 13.5 0.4 0.37 10.7 0.0 2.5 2 1 1 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal ChAPs PF09295.10 EKX47834.1 - 0.1 11.6 1.5 6.9 5.6 0.4 2.4 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Clathrin PF00637.20 EKX47834.1 - 0.14 12.0 3.7 1.3 8.9 0.0 3.6 4 1 0 4 4 3 0 Region in Clathrin and VPS BTAD PF03704.17 EKX47834.1 - 0.79 10.2 7.8 0.12 12.8 0.6 3.1 2 1 0 2 2 2 0 Bacterial transcriptional activator domain MIT PF04212.18 EKX47834.1 - 0.98 9.5 9.9 35 4.6 0.1 6.6 8 1 0 8 8 5 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 EKX47834.1 - 2.4 8.3 4.2 5.5 7.2 0.0 3.5 5 0 0 5 5 2 0 Fis1 C-terminal tetratricopeptide repeat PPR_1 PF12854.7 EKX47834.1 - 2.5 7.9 8.5 28 4.5 0.1 4.3 5 0 0 5 5 4 0 PPR repeat DUF4810 PF16068.5 EKX47834.1 - 4.7 7.8 7.0 10 6.7 0.1 4.5 6 1 0 6 6 4 0 Domain of unknown function (DUF4810) PAS_9 PF13426.7 EKX47835.1 - 0.0041 17.4 0.1 0.047 14.0 0.0 2.1 1 1 1 2 2 2 1 PAS domain Aldo_ket_red PF00248.21 EKX47836.1 - 6.9e-76 255.2 0.0 7.9e-76 255.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-Tim10_DDP PF02953.15 EKX47837.1 - 4e-19 68.0 0.4 4.2e-19 68.0 0.4 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger CAF1C_H4-bd PF12265.8 EKX47838.1 - 4.3e-09 36.5 0.3 9.8e-09 35.4 0.3 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EKX47838.1 - 2.3e-06 28.2 13.8 0.00074 20.3 0.3 4.8 3 1 1 4 4 4 2 WD domain, G-beta repeat MatE PF01554.18 EKX47839.1 - 2.2e-16 59.9 37.2 5.8e-07 29.3 11.9 3.6 4 0 0 4 4 4 3 MatE Viral_DNA_bp PF00747.17 EKX47839.1 - 0.016 12.4 0.0 0.023 11.9 0.0 1.1 1 0 0 1 1 1 0 ssDNA binding protein AAA_6 PF12774.7 EKX47840.1 - 2.6e-138 460.5 0.0 1.2e-137 458.4 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EKX47840.1 - 3.7e-101 339.1 11.1 3.7e-101 339.1 11.1 2.8 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EKX47840.1 - 2.5e-94 315.5 0.0 1.4e-93 313.0 0.0 2.3 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EKX47840.1 - 9.8e-84 279.9 2.7 3.7e-83 278.0 2.7 2.1 1 0 0 1 1 1 1 ATP-binding dynein motor region Dynein_C PF18199.1 EKX47840.1 - 2.1e-82 276.8 0.0 1.5e-81 274.0 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain MT PF12777.7 EKX47840.1 - 2.5e-80 270.1 17.2 4.4e-80 269.3 17.2 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 EKX47840.1 - 1.2e-65 220.4 0.2 2.6e-61 206.3 0.0 3.6 3 0 0 3 3 3 2 P-loop containing dynein motor region Kelch_4 PF13418.6 EKX47840.1 - 5.7e-50 167.1 7.7 2.7e-09 36.9 0.2 9.6 9 0 0 9 9 9 5 Galactose oxidase, central domain AAA_lid_11 PF18198.1 EKX47840.1 - 5.1e-40 137.0 0.0 1.8e-39 135.2 0.0 2.0 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Kelch_5 PF13854.6 EKX47840.1 - 1.2e-39 133.7 0.3 1.6e-06 27.9 0.0 11.1 11 0 0 11 11 11 6 Kelch motif Dynein_heavy PF03028.15 EKX47840.1 - 1.9e-32 111.8 0.0 1.3e-31 109.2 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Kelch_1 PF01344.25 EKX47840.1 - 9.6e-31 105.1 8.6 7.3e-06 25.5 0.1 10.1 10 0 0 10 10 9 6 Kelch motif Kelch_3 PF13415.6 EKX47840.1 - 3.5e-29 100.5 10.5 6.2e-07 29.6 0.0 10.4 11 0 0 11 11 10 5 Galactose oxidase, central domain AAA_lid_1 PF17857.1 EKX47840.1 - 1.8e-25 89.0 2.2 7.1e-25 87.1 0.4 2.7 2 0 0 2 2 2 1 AAA+ lid domain Kelch_6 PF13964.6 EKX47840.1 - 6.9e-25 86.5 12.4 9.6e-07 28.9 0.1 9.6 10 1 1 11 11 10 5 Kelch motif Kelch_2 PF07646.15 EKX47840.1 - 1.8e-23 81.6 11.8 1.1e-05 25.2 0.1 11.0 11 0 0 11 11 11 3 Kelch motif Dynein_AAA_lid PF17852.1 EKX47840.1 - 1.1e-22 80.5 0.9 3.3e-22 78.9 0.9 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Filamin PF00630.19 EKX47840.1 - 3.7e-15 56.6 0.0 9.7e-15 55.3 0.0 1.8 1 0 0 1 1 1 1 Filamin/ABP280 repeat AAA_5 PF07728.14 EKX47840.1 - 6.8e-12 45.6 0.0 2.5e-07 30.8 0.0 4.9 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) TIG PF01833.24 EKX47840.1 - 6.4e-05 22.9 0.0 0.00017 21.6 0.0 1.7 1 0 0 1 1 1 1 IPT/TIG domain AAA_22 PF13401.6 EKX47840.1 - 7.4e-05 23.0 0.0 1.4 9.2 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 EKX47840.1 - 9.3e-05 23.0 0.1 1.2 9.6 0.0 4.3 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 EKX47840.1 - 0.0033 17.8 0.2 12 6.2 0.0 4.1 4 0 0 4 4 3 0 AAA ATPase domain CbiA PF01656.23 EKX47840.1 - 0.0056 16.7 0.0 0.13 12.3 0.0 2.7 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_28 PF13521.6 EKX47840.1 - 0.0097 16.2 0.8 0.67 10.2 0.0 3.3 3 0 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 EKX47840.1 - 0.012 15.6 0.1 1.1 9.2 0.0 3.3 3 0 0 3 3 3 0 RsgA GTPase ABC_tran PF00005.27 EKX47840.1 - 0.091 13.3 0.3 2.2 8.8 0.0 3.4 3 0 0 3 3 2 0 ABC transporter AAA_29 PF13555.6 EKX47840.1 - 0.11 12.2 0.2 12 5.7 0.0 3.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain Dermcidin PF15291.6 EKX47840.1 - 0.65 10.6 3.1 1.9 9.1 3.1 1.8 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide AAA_19 PF13245.6 EKX47840.1 - 0.72 10.2 4.5 52 4.2 0.0 4.2 4 0 0 4 4 4 0 AAA domain AAA PF00004.29 EKX47840.1 - 3.1 8.2 12.9 25 5.3 0.1 5.4 6 0 0 6 6 4 0 ATPase family associated with various cellular activities (AAA) PGM_PMM_III PF02880.16 EKX47841.1 - 2.8e-24 85.5 0.0 5.5e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_I PF02878.16 EKX47841.1 - 8.5e-24 83.8 0.2 2.9e-23 82.1 0.2 1.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 EKX47841.1 - 3.7e-08 33.9 0.4 2e-07 31.6 0.2 2.3 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EKX47841.1 - 3.7e-05 23.8 0.0 8.5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Ham1p_like PF01725.16 EKX47841.1 - 0.1 12.5 0.1 0.94 9.4 0.1 2.1 1 1 0 1 1 1 0 Ham1 family Spc7 PF08317.11 EKX47842.1 - 0.072 12.0 6.0 0.1 11.5 6.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein EpmC PF04315.12 EKX47842.1 - 0.12 12.0 0.4 0.78 9.4 0.0 2.1 2 0 0 2 2 2 0 Elongation factor P hydroxylase zf-C4H2 PF10146.9 EKX47842.1 - 0.39 11.0 3.4 0.77 10.0 2.7 1.8 1 1 0 1 1 1 0 Zinc finger-containing protein DEDD_Tnp_IS110 PF01548.17 EKX47842.1 - 0.54 10.1 4.2 5.6 6.8 0.1 2.4 2 1 0 2 2 2 0 Transposase XhlA PF10779.9 EKX47842.1 - 0.65 10.3 3.2 3.5 7.9 0.2 2.4 2 0 0 2 2 2 0 Haemolysin XhlA COG2 PF06148.11 EKX47842.1 - 0.82 9.8 5.6 0.16 12.0 1.4 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 SKA1 PF07160.12 EKX47842.1 - 5.2 6.8 11.1 7 6.4 1.3 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 Collagen PF01391.18 EKX47843.1 - 6.2e-28 96.3 91.3 3e-09 36.5 27.7 3.6 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Collagen PF01391.18 EKX47844.1 - 8.5e-26 89.5 86.1 2.6e-09 36.7 27.1 3.5 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) DEAD PF00270.29 EKX47845.1 - 2.1e-45 154.7 0.0 3.5e-45 153.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX47845.1 - 5e-21 75.1 0.0 1.7e-20 73.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EKX47845.1 - 2.5e-18 66.0 0.1 4.8e-18 65.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EKX47845.1 - 4.1e-08 33.4 0.7 1.7e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Mpp10 PF04006.12 EKX47845.1 - 0.00079 18.0 16.4 0.00079 18.0 16.4 1.6 2 0 0 2 2 2 1 Mpp10 protein SAPS PF04499.15 EKX47845.1 - 0.55 9.0 5.6 4.6 5.9 7.4 1.6 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein BSP_II PF05432.11 EKX47845.1 - 1.4 8.6 32.2 2.9 7.5 32.2 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Hid1 PF12722.7 EKX47845.1 - 2.3 6.2 6.4 3.6 5.6 6.4 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 EKX47845.1 - 3.2 6.4 12.1 2.4 6.9 10.0 1.7 2 0 0 2 2 2 0 Presenilin Cyclin_N PF00134.23 EKX47846.1 - 3.2e-19 68.9 0.5 1.9e-18 66.4 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EKX47846.1 - 0.00051 20.1 2.4 0.00058 19.9 0.1 2.1 2 1 0 2 2 2 1 Cyclin, C-terminal domain DUF3304 PF11745.8 EKX47847.1 - 0.54 10.7 2.6 24 5.4 0.4 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3304) ABC1 PF03109.16 EKX47847.1 - 2.7 8.2 6.7 1.5 9.0 1.6 2.9 1 1 1 2 2 2 0 ABC1 family Speriolin_N PF15058.6 EKX47847.1 - 8.5 6.4 12.3 6.1 6.9 1.9 2.6 2 1 0 2 2 2 0 Speriolin N terminus MFS_1_like PF12832.7 EKX47848.1 - 2.1e-26 92.7 14.3 3.7e-26 91.9 14.3 1.4 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 EKX47848.1 - 2.5e-12 46.4 26.8 2.6e-11 43.0 13.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SHS2_Rpb7-N PF03876.17 EKX47849.1 - 2.7e-09 37.3 0.0 5.2e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EKX47849.1 - 6.3e-07 29.7 0.0 1.1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 EKX47849.1 - 0.0014 18.9 0.0 0.0022 18.2 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 Acyl_transf_3 PF01757.22 EKX47850.1 - 3.2e-07 29.8 30.5 9.1e-07 28.3 30.5 1.8 1 0 0 1 1 1 1 Acyltransferase family AAA_11 PF13086.6 EKX47851.1 - 0.0013 18.6 1.3 0.0014 18.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EKX47851.1 - 0.0032 17.1 0.0 0.006 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EKX47851.1 - 0.0065 16.9 0.0 0.017 15.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX47851.1 - 0.0076 16.6 0.1 0.066 13.6 0.1 2.2 1 1 2 3 3 3 1 AAA ATPase domain AAA_7 PF12775.7 EKX47851.1 - 0.013 15.0 0.1 0.05 13.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region GvpD PF07088.11 EKX47851.1 - 0.084 11.5 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_22 PF13401.6 EKX47851.1 - 0.097 12.9 0.1 0.42 10.9 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EKX47851.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EKX47851.1 - 0.12 12.9 0.5 0.46 11.0 0.2 2.2 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EKX47851.1 - 0.16 11.9 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EKX47851.1 - 0.18 12.1 0.0 0.61 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain YccF PF03733.13 EKX47852.1 - 1e-32 112.6 27.5 4.1e-18 65.8 9.3 2.1 2 0 0 2 2 2 2 Inner membrane component domain DUF3930 PF13067.6 EKX47852.1 - 0.025 14.8 1.2 0.79 10.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3930) DUF3487 PF11990.8 EKX47852.1 - 0.055 13.4 1.4 0.055 13.4 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) DUF5362 PF17319.2 EKX47852.1 - 1.5 8.7 9.2 0.14 12.0 1.1 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5362) RCC1_2 PF13540.6 EKX47853.1 - 2e-28 97.5 45.0 9.6e-07 28.5 1.9 7.1 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EKX47853.1 - 1.7e-07 31.8 31.6 0.019 15.6 0.3 6.5 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat DUF3034 PF11231.8 EKX47853.1 - 0.058 12.9 0.2 6.1 6.3 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3034) Ephrin_rec_like PF07699.13 EKX47854.1 - 0.021 14.6 6.2 1.4 8.7 2.5 2.8 3 0 0 3 3 3 0 Putative ephrin-receptor like FA_desaturase PF00487.24 EKX47855.1 - 1.3e-14 54.7 22.0 1.3e-14 54.7 22.0 1.6 1 1 1 2 2 2 1 Fatty acid desaturase AAA PF00004.29 EKX47856.1 - 2.7e-41 141.1 0.0 4.3e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EKX47856.1 - 1.7e-09 37.3 0.1 4.1e-09 36.1 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EKX47856.1 - 2.2e-07 31.1 0.0 4.2e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EKX47856.1 - 1e-05 26.0 0.5 5.7e-05 23.6 0.5 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EKX47856.1 - 5.5e-05 23.2 0.0 0.00071 19.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EKX47856.1 - 5.6e-05 23.0 0.0 8.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 EKX47856.1 - 0.00011 22.4 0.3 0.0055 17.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 EKX47856.1 - 0.00069 20.0 0.0 0.001 19.4 0.0 1.3 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 EKX47856.1 - 0.0014 18.1 0.1 0.0022 17.4 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 EKX47856.1 - 0.0021 17.8 0.1 0.0081 15.9 0.0 2.0 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 EKX47856.1 - 0.0034 17.3 0.3 0.01 15.8 0.2 1.9 1 1 0 1 1 1 1 NACHT domain AAA_7 PF12775.7 EKX47856.1 - 0.0054 16.3 0.0 0.009 15.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 EKX47856.1 - 0.0055 16.9 0.1 0.0071 16.5 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EKX47856.1 - 0.0071 16.9 0.0 0.0095 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EKX47856.1 - 0.0092 15.6 0.1 0.024 14.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EKX47856.1 - 0.011 15.5 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EKX47856.1 - 0.016 15.1 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EKX47856.1 - 0.019 14.7 0.0 0.087 12.5 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 EKX47856.1 - 0.023 13.8 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 EKX47856.1 - 0.023 15.2 0.0 0.035 14.6 0.0 1.3 1 0 0 1 1 1 0 ABC transporter TIP49 PF06068.13 EKX47856.1 - 0.024 13.8 0.0 0.033 13.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 EKX47856.1 - 0.027 14.7 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EKX47856.1 - 0.032 14.0 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EKX47856.1 - 0.033 14.2 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 EKX47856.1 - 0.048 13.6 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 EKX47856.1 - 0.061 12.5 0.0 0.077 12.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 EKX47856.1 - 0.11 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ATPase PF06745.13 EKX47856.1 - 0.12 11.7 0.2 0.23 10.8 0.0 1.5 2 0 0 2 2 2 0 KaiC PhoH PF02562.16 EKX47856.1 - 0.18 11.3 0.1 0.3 10.5 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Bromodomain PF00439.25 EKX47857.1 - 9.9e-16 57.6 0.0 1.1e-15 57.4 0.0 1.0 1 0 0 1 1 1 1 Bromodomain Ubiquitin_2 PF14560.6 EKX47858.1 - 2.8e-23 82.2 0.0 5.1e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 EKX47858.1 - 6.9e-23 80.4 2.7 6.9e-23 80.4 2.7 1.6 2 0 0 2 2 2 1 CAP-Gly domain CAF-1_p60_C PF15512.6 EKX47860.1 - 0.01 16.4 2.3 0.013 16.0 0.6 1.9 2 0 0 2 2 2 0 Chromatin assembly factor complex 1 subunit p60, C-terminal DUF5329 PF17263.2 EKX47860.1 - 0.15 12.3 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5329) IF3_C PF00707.22 EKX47862.1 - 6.9e-20 70.8 0.1 1.1e-19 70.2 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 EKX47862.1 - 2.5e-06 27.6 0.9 5.1e-06 26.7 0.9 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain Pep_M12B_propep PF01562.19 EKX47862.1 - 0.021 15.1 0.1 0.023 14.9 0.1 1.1 1 0 0 1 1 1 0 Reprolysin family propeptide Trigger_N PF05697.13 EKX47863.1 - 1.4e-13 51.4 1.1 1.8e-13 51.0 1.1 1.1 1 0 0 1 1 1 1 Bacterial trigger factor protein (TF) Spindle_Spc25 PF08234.12 EKX47863.1 - 0.094 12.9 0.1 1.6 9.0 0.2 2.4 2 0 0 2 2 2 0 Chromosome segregation protein Spc25 Mod_r PF07200.13 EKX47864.1 - 8.3e-11 42.2 13.0 1.1e-10 41.9 13.0 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein PhoU PF01895.19 EKX47864.1 - 0.053 14.0 5.1 0.98 9.9 1.0 2.3 1 1 1 2 2 2 0 PhoU domain DUF2203 PF09969.9 EKX47864.1 - 0.056 14.2 3.9 0.049 14.4 2.3 1.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Zmiz1_N PF18028.1 EKX47864.1 - 0.068 13.5 1.5 0.87 9.9 0.1 2.6 1 1 1 2 2 2 0 Zmiz1 N-terminal tetratricopeptide repeat domain DUF3138 PF11336.8 EKX47864.1 - 0.26 9.8 1.7 0.33 9.5 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Cnn_1N PF07989.11 EKX47864.1 - 1.7 8.8 13.5 0.11 12.6 4.5 3.2 3 1 1 4 4 4 0 Centrosomin N-terminal motif 1 DUF883 PF05957.13 EKX47864.1 - 4.1 8.1 11.5 0.25 12.0 5.2 2.2 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Spc24 PF08286.11 EKX47864.1 - 7.5 6.9 9.6 4.2 7.7 6.4 2.4 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Orai-1 PF07856.12 EKX47865.1 - 1.5e-09 37.8 1.3 2.1e-09 37.3 1.3 1.2 1 0 0 1 1 1 1 Mediator of CRAC channel activity Jiraiya PF15038.6 EKX47865.1 - 1.5 8.3 7.8 0.69 9.3 0.9 2.3 2 0 0 2 2 2 0 Jiraiya FixH PF05751.11 EKX47865.1 - 2.8 7.9 5.9 0.92 9.5 0.3 2.1 2 0 0 2 2 2 0 FixH Steroid_dh PF02544.16 EKX47866.1 - 1.3e-55 187.5 1.1 1.3e-55 187.5 1.1 1.6 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EKX47866.1 - 8.4e-05 22.2 0.5 8.4e-05 22.2 0.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) REV PF00424.18 EKX47866.1 - 0.22 11.6 5.0 0.38 10.8 5.0 1.3 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Ank_4 PF13637.6 EKX47867.1 - 3.1e-09 37.2 0.7 7.5e-07 29.6 0.7 2.7 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX47867.1 - 2.8e-07 31.0 0.1 0.005 17.4 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX47867.1 - 4.7e-07 30.0 0.4 0.0032 17.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX47867.1 - 8.4e-06 25.8 0.2 0.089 13.4 0.0 3.3 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EKX47867.1 - 0.00011 22.4 6.3 0.064 13.7 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat FAM176 PF14851.6 EKX47867.1 - 1.1 8.9 10.1 30 4.3 0.0 2.7 2 0 0 2 2 2 0 FAM176 family Ion_trans PF00520.31 EKX47868.1 - 5.4e-75 251.8 56.3 2.4e-34 118.7 7.6 4.4 4 1 0 4 4 4 4 Ion transport protein GoLoco PF02188.17 EKX47868.1 - 0.62 9.6 2.6 2.2 7.9 2.6 2.1 1 0 0 1 1 1 0 GoLoco motif SPRY PF00622.28 EKX47869.1 - 0.00054 20.1 0.1 0.0014 18.8 0.1 1.7 1 0 0 1 1 1 1 SPRY domain HAD_SAK_1 PF10307.9 EKX47869.1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 HAD domain family 1 in Swiss Army Knife RNA repair proteins TAP_C PF03943.13 EKX47870.1 - 0.03 13.9 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 TAP C-terminal domain MPC PF03650.13 EKX47871.1 - 2.4e-38 130.7 0.9 2.8e-38 130.5 0.9 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Yippee-Mis18 PF03226.14 EKX47872.1 - 8.6e-15 54.8 0.6 1.1e-14 54.5 0.6 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Jas PF16135.5 EKX47872.1 - 0.095 12.9 0.2 0.095 12.9 0.2 1.8 1 1 0 2 2 2 0 TPL-binding domain in jasmonate signalling EF-hand_1 PF00036.32 EKX47873.1 - 3.6e-23 79.3 15.2 4.1e-07 29.1 0.2 8.0 9 0 0 9 9 9 4 EF hand EF-hand_7 PF13499.6 EKX47873.1 - 6.9e-22 77.7 10.9 1e-09 38.7 0.7 6.8 6 0 0 6 6 6 3 EF-hand domain pair EF-hand_6 PF13405.6 EKX47873.1 - 3.9e-19 66.9 9.3 9e-06 25.2 0.1 8.0 8 0 0 8 8 8 4 EF-hand domain EF-hand_8 PF13833.6 EKX47873.1 - 7.9e-19 67.3 18.4 4.4e-09 36.0 0.1 7.0 7 1 1 8 8 8 4 EF-hand domain pair EF-hand_5 PF13202.6 EKX47873.1 - 1.4e-13 49.7 10.1 5.4e-06 25.7 0.2 5.0 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 EKX47873.1 - 2.8e-07 30.4 4.1 0.0047 16.8 0.2 4.3 4 0 0 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 EKX47873.1 - 0.0022 17.8 0.3 1.3 9.0 0.1 4.0 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 EKX47873.1 - 0.0027 18.0 0.1 0.77 10.1 0.0 3.3 4 0 0 4 4 3 1 EF-hand domain SPARC_Ca_bdg PF10591.9 EKX47873.1 - 0.14 12.5 0.1 0.14 12.5 0.1 3.7 4 1 0 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region YebG PF07130.12 EKX47873.1 - 0.14 12.0 2.7 0.42 10.5 0.4 3.1 3 0 0 3 3 3 0 YebG protein FAM76 PF16046.5 EKX47873.1 - 4 6.7 21.1 0.015 14.7 7.6 3.1 3 0 0 3 3 3 0 FAM76 protein adh_short_C2 PF13561.6 EKX47874.1 - 0.0071 15.9 0.1 0.011 15.4 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase PGA_cap PF09587.10 EKX47874.1 - 0.084 12.3 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap TIG PF01833.24 EKX47875.1 - 9.5e-41 137.8 83.1 8.2e-05 22.6 0.0 24.4 24 0 0 24 24 24 12 IPT/TIG domain EPTP PF03736.17 EKX47875.1 - 3.5e-22 78.1 32.5 1.6e-05 24.8 0.1 11.6 11 0 0 11 11 11 6 EPTP domain Laminin_G_3 PF13385.6 EKX47875.1 - 3.1e-14 53.4 1.6 1.2e-13 51.5 0.3 3.0 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Anth_Ig PF05587.13 EKX47875.1 - 6.7e-13 48.8 12.5 0.64 10.4 0.0 11.9 12 0 0 12 12 12 3 Anthrax receptor extracellular domain Lactonase PF10282.9 EKX47875.1 - 1e-08 34.9 0.3 0.0012 18.2 0.1 3.6 3 0 0 3 3 3 2 Lactonase, 7-bladed beta-propeller Big_9 PF17963.1 EKX47875.1 - 0.00022 21.9 55.0 0.32 11.8 3.0 15.5 17 1 0 17 17 17 3 Bacterial Ig domain TIG_2 PF18020.1 EKX47875.1 - 0.017 15.7 1.2 38 5.0 0.0 6.2 6 0 0 6 6 6 0 TIG domain found in plexin Cadherin_3 PF16184.5 EKX47875.1 - 4.4 7.4 7.6 25 4.9 0.1 4.8 6 0 0 6 6 6 0 Cadherin-like Usp PF00582.26 EKX47876.1 - 1.2e-10 42.0 0.0 0.0003 21.3 0.0 2.4 2 0 0 2 2 2 2 Universal stress protein family SAP30_Sin3_bdg PF13867.6 EKX47878.1 - 0.012 16.0 0.6 11 6.5 0.0 3.0 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Comm PF15957.5 EKX47879.1 - 0.041 14.2 0.7 0.13 12.6 0.0 2.1 2 0 0 2 2 2 0 Commissureless Sortilin_C PF15901.5 EKX47879.1 - 0.051 13.9 0.3 0.09 13.1 0.3 1.3 1 0 0 1 1 1 0 Sortilin, neurotensin receptor 3, C-terminal DUF2057 PF09829.9 EKX47880.1 - 0.012 15.8 2.0 0.016 15.4 2.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) FSA_C PF10479.9 EKX47880.1 - 0.017 13.3 5.6 0.021 13.0 5.6 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Mucin PF01456.17 EKX47880.1 - 1.7 8.6 22.4 2.6 8.0 22.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Adeno_PV PF03910.13 EKX47880.1 - 9.7 4.8 9.0 13 4.3 9.0 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV MMR_HSR1 PF01926.23 EKX47881.1 - 4.6e-18 65.4 0.0 6.6e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EKX47881.1 - 0.00059 19.4 0.1 0.014 14.9 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B ABC_tran PF00005.27 EKX47881.1 - 0.0079 16.7 0.0 0.014 15.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Dynamin_N PF00350.23 EKX47881.1 - 0.012 15.6 0.0 0.063 13.3 0.0 2.0 2 0 0 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 EKX47881.1 - 0.018 14.9 0.0 2.5 8.0 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 EKX47881.1 - 0.018 14.6 0.0 9.2 5.7 0.0 2.8 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain MeaB PF03308.16 EKX47881.1 - 0.11 11.5 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Kelch_5 PF13854.6 EKX47882.1 - 2.4e-39 132.7 31.2 4.1e-05 23.5 0.0 14.7 16 0 0 16 16 16 10 Kelch motif Kelch_4 PF13418.6 EKX47882.1 - 1.5e-28 98.5 35.6 4.2e-05 23.5 0.1 13.6 13 0 0 13 13 13 7 Galactose oxidase, central domain Filamin PF00630.19 EKX47882.1 - 4.2e-26 91.8 0.0 2.7e-14 53.8 0.0 3.9 4 0 0 4 4 4 3 Filamin/ABP280 repeat Kelch_3 PF13415.6 EKX47882.1 - 4e-25 87.6 60.3 0.013 15.8 0.2 19.4 20 1 0 20 20 20 7 Galactose oxidase, central domain Kelch_1 PF01344.25 EKX47882.1 - 1.3e-20 72.7 17.3 0.00011 21.7 0.0 11.3 12 0 0 12 12 12 5 Kelch motif Laminin_G_3 PF13385.6 EKX47882.1 - 6.6e-18 65.3 2.2 3.4e-17 63.0 2.2 2.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Kelch_6 PF13964.6 EKX47882.1 - 3.4e-16 58.9 35.2 0.0058 16.9 0.1 13.6 13 0 0 13 13 13 5 Kelch motif Laminin_G_2 PF02210.24 EKX47882.1 - 0.001 19.6 0.4 0.059 14.0 0.1 2.6 2 0 0 2 2 2 1 Laminin G domain Kelch_2 PF07646.15 EKX47882.1 - 0.0014 18.5 35.4 0.0016 18.3 0.1 11.0 13 0 0 13 13 13 2 Kelch motif Pentaxin PF00354.17 EKX47882.1 - 0.0031 17.2 0.7 0.0089 15.7 0.7 1.7 1 0 0 1 1 1 1 Pentaxin family Ank_4 PF13637.6 EKX47883.1 - 1.1e-21 76.8 6.2 7.9e-14 51.8 0.4 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX47883.1 - 2.3e-17 63.3 0.8 3.3e-11 43.6 0.5 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX47883.1 - 5.9e-16 57.0 1.6 8e-07 28.9 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 EKX47883.1 - 7.2e-15 54.7 2.3 2.8e-07 30.7 0.2 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EKX47883.1 - 4.2e-14 52.4 1.9 9.7e-10 38.5 0.3 2.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Pkinase PF00069.25 EKX47884.1 - 2.2e-63 214.1 0.0 2.5e-63 213.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX47884.1 - 2.9e-44 151.3 0.0 3.2e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX47884.1 - 2.4e-07 29.9 0.0 5.8e-07 28.6 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EKX47884.1 - 0.0008 18.8 0.0 0.0011 18.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EKX47884.1 - 0.0067 15.8 0.0 0.0093 15.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_4 PF12799.7 EKX47885.1 - 2.6e-24 84.9 27.1 2.4e-08 34.1 2.2 6.0 3 2 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX47885.1 - 3.9e-18 65.0 19.9 2.3e-08 33.7 2.1 4.7 3 1 2 5 5 5 5 Leucine rich repeat LRR_6 PF13516.6 EKX47885.1 - 7.6e-11 41.2 18.2 0.72 10.1 0.2 8.8 9 0 0 9 9 9 6 Leucine Rich repeat LRR_9 PF14580.6 EKX47885.1 - 3.1e-10 39.9 10.4 1.6e-06 27.7 4.2 2.6 1 1 0 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 EKX47885.1 - 3.1e-05 23.9 16.9 3.5 8.5 0.3 7.5 7 1 1 8 8 8 3 Leucine Rich Repeat MMR_HSR1 PF01926.23 EKX47886.1 - 2e-14 53.6 0.7 3.8e-13 49.5 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EKX47886.1 - 9.9e-09 35.3 0.1 3.3e-08 33.6 0.1 1.8 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 EKX47886.1 - 2.8e-05 23.7 1.4 0.00043 19.8 0.4 2.6 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EKX47886.1 - 4.4e-05 23.1 0.2 0.011 15.3 0.0 2.4 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain IIGP PF05049.13 EKX47886.1 - 0.026 13.6 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Septin PF00735.18 EKX47886.1 - 0.05 12.9 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Septin Dynamin_N PF00350.23 EKX47886.1 - 0.062 13.4 1.2 12 5.9 0.0 2.8 2 1 1 3 3 3 0 Dynamin family SRPRB PF09439.10 EKX47886.1 - 0.078 12.4 0.1 0.19 11.1 0.1 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Arf PF00025.21 EKX47886.1 - 0.082 12.3 0.5 1.1 8.7 0.1 2.2 1 1 1 2 2 2 0 ADP-ribosylation factor family AAA_33 PF13671.6 EKX47886.1 - 0.089 12.9 0.1 5.8 7.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 EKX47887.1 - 5.4e-20 71.4 4.6 6.9e-07 29.9 0.0 6.2 5 1 0 5 5 5 3 WD domain, G-beta repeat C2 PF00168.30 EKX47887.1 - 1.3e-12 47.9 0.0 3.4e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain Nup160 PF11715.8 EKX47887.1 - 6.5e-08 31.7 0.6 0.00015 20.6 0.1 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 EKX47887.1 - 0.00037 20.9 1.2 22 5.7 0.0 4.9 5 0 0 5 5 5 1 PQQ-like domain PQQ_2 PF13360.6 EKX47887.1 - 0.0056 16.3 0.0 0.017 14.7 0.0 1.8 2 0 0 2 2 2 1 PQQ-like domain ANAPC4_WD40 PF12894.7 EKX47887.1 - 0.014 15.7 0.3 5.5 7.4 0.0 3.8 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Rhabdo_ncap PF00945.18 EKX47887.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein C2 PF00168.30 EKX47888.1 - 3.6e-20 72.2 0.0 7.2e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain SpoU_methylase PF00588.19 EKX47889.1 - 1.5e-20 73.8 0.0 1.8e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 SpoU rRNA Methylase family Pkinase PF00069.25 EKX47890.1 - 2.9e-20 72.7 0.0 4e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX47890.1 - 1.8e-17 63.5 0.0 2.6e-17 63.0 0.0 1.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX47892.1 - 4.7e-44 150.7 0.0 6.1e-44 150.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX47892.1 - 5.1e-26 91.5 0.0 6.4e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX47892.1 - 0.0053 16.1 0.0 0.0085 15.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EKX47892.1 - 0.0099 14.7 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EKX47892.1 - 0.066 12.1 0.0 0.094 11.6 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EKX47892.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX47892.1 - 0.14 12.1 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family MoCF_biosynth PF00994.24 EKX47893.1 - 1.3e-30 106.0 0.0 2.6e-30 105.0 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain CinA_KH PF18146.1 EKX47893.1 - 0.1 12.8 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 Damage-inducible protein CinA KH domain TSC22 PF01166.18 EKX47894.1 - 0.0088 16.3 1.6 0.0088 16.3 1.6 4.1 4 0 0 4 4 4 2 TSC-22/dip/bun family TPR_MLP1_2 PF07926.12 EKX47894.1 - 1.2 9.2 41.5 0.09 12.8 11.7 3.0 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 EKX47894.1 - 2.2 7.5 21.1 0.12 11.7 6.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) SseC PF04888.12 EKX47894.1 - 2.8 7.4 9.2 0.93 9.0 0.5 2.5 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family XhlA PF10779.9 EKX47894.1 - 7 6.9 20.4 13 6.1 9.0 4.6 4 1 0 4 4 4 0 Haemolysin XhlA ATG16 PF08614.11 EKX47894.1 - 8.1 6.6 39.5 0.11 12.7 14.4 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Glyco_transf_41 PF13844.6 EKX47895.1 - 2.6e-41 141.6 0.0 5e-37 127.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_2 PF07719.17 EKX47895.1 - 2.3e-14 52.2 26.2 0.0025 17.8 2.4 5.6 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.6 EKX47895.1 - 7e-14 52.2 18.5 1.5e-06 28.8 6.9 4.0 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 EKX47895.1 - 1.8e-13 49.5 9.8 0.0024 17.8 0.5 5.8 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 EKX47895.1 - 7.5e-13 48.6 18.5 9.6e-05 22.6 1.6 4.4 3 2 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX47895.1 - 1.9e-12 46.9 18.7 7.2e-05 23.3 2.2 6.5 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 EKX47895.1 - 2e-11 43.2 18.3 0.0097 15.7 1.6 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 EKX47895.1 - 1.8e-09 38.0 13.6 1.7e-07 31.6 4.8 4.3 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX47895.1 - 6.5e-08 32.2 18.9 0.038 14.2 0.5 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 EKX47895.1 - 1.5e-07 30.9 9.2 5.3e-07 29.1 8.4 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 EKX47895.1 - 8.6e-07 29.5 5.7 8.6e-07 29.5 5.7 2.6 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_10 PF13374.6 EKX47895.1 - 3.4e-06 26.8 21.0 0.34 10.9 0.2 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX47895.1 - 3.4e-06 27.2 10.4 0.0002 21.5 4.0 2.5 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EKX47895.1 - 0.00052 20.2 10.1 0.0036 17.6 0.8 4.1 4 1 0 4 4 3 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EKX47895.1 - 0.0016 18.5 3.8 0.0032 17.5 3.8 1.5 1 0 0 1 1 1 1 Putative TPR-like repeat TPR_11 PF13414.6 EKX47895.1 - 0.0022 17.6 15.3 2.9 7.7 0.1 4.6 3 1 1 4 4 4 3 TPR repeat SNAP PF14938.6 EKX47895.1 - 0.0076 15.7 2.9 0.0076 15.7 2.9 2.4 2 1 1 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_5 PF12688.7 EKX47895.1 - 0.011 15.9 3.8 0.026 14.8 0.4 3.1 4 0 0 4 4 3 0 Tetratrico peptide repeat Fis1_TPR_C PF14853.6 EKX47895.1 - 0.014 15.4 7.6 0.027 14.6 0.5 3.0 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat Coatomer_E PF04733.14 EKX47895.1 - 0.033 13.6 0.5 0.066 12.6 0.2 1.5 1 1 0 1 1 1 0 Coatomer epsilon subunit HrpB7 PF09486.10 EKX47895.1 - 0.036 14.5 0.2 0.1 13.0 0.2 1.9 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Paf67 PF10255.9 EKX47895.1 - 0.057 12.4 0.4 0.1 11.6 0.4 1.3 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 NARP1 PF12569.8 EKX47895.1 - 0.14 11.0 4.5 0.71 8.7 4.7 1.8 1 1 0 1 1 1 0 NMDA receptor-regulated protein 1 ImpA_N PF06812.12 EKX47895.1 - 0.16 12.1 2.3 0.29 11.3 0.5 2.2 1 1 1 2 2 2 0 ImpA, N-terminal, type VI secretion system TPR_9 PF13371.6 EKX47895.1 - 0.35 11.0 16.5 0.94 9.7 3.4 4.2 2 1 3 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX47895.1 - 0.42 11.3 18.6 6.7 7.6 0.3 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 EKX47895.1 - 1.2 9.3 13.5 15 5.7 0.1 4.4 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.9 EKX47895.1 - 2.6 7.6 4.9 56 3.3 0.1 3.6 4 0 0 4 4 3 0 SHNi-TPR RRM_1 PF00076.22 EKX47896.1 - 7.6e-13 48.1 0.0 1.3e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EKX47896.1 - 0.073 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Glyco_transf_41 PF13844.6 EKX47897.1 - 4.9e-109 364.9 0.2 5e-54 183.5 0.2 2.0 1 1 1 2 2 2 2 Glycosyl transferase family 41 ADH_zinc_N PF00107.26 EKX47898.1 - 8.4e-30 103.4 0.7 1.2e-29 102.9 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EKX47898.1 - 7.4e-18 65.9 0.0 1.3e-17 65.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EKX47898.1 - 9.3e-05 22.3 1.4 0.00051 19.9 1.4 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PGM_PMM_III PF02880.16 EKX47898.1 - 0.037 14.2 0.0 9.1 6.5 0.1 2.6 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III NAD_binding_10 PF13460.6 EKX47898.1 - 0.063 13.2 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Methyltr_RsmB-F PF01189.17 EKX47898.1 - 0.082 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F zf-AN1 PF01428.16 EKX47899.1 - 3.4e-06 27.1 8.8 9e-06 25.8 8.8 1.7 1 0 0 1 1 1 1 AN1-like Zinc finger ubiquitin PF00240.23 EKX47899.1 - 6.6e-06 25.8 0.4 1.4e-05 24.7 0.4 1.6 1 1 0 1 1 1 1 Ubiquitin family Ank_5 PF13857.6 EKX47900.1 - 4.1e-11 42.9 3.6 5.9e-07 29.6 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX47900.1 - 1.1e-09 38.7 0.1 3.4e-09 37.2 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX47900.1 - 2e-09 37.5 0.4 7.5e-06 26.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EKX47900.1 - 3e-09 37.2 0.6 0.00067 20.2 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX47900.1 - 2.6e-06 27.3 0.1 0.0037 17.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat DUF572 PF04502.13 EKX47900.1 - 0.039 13.6 16.8 0.045 13.4 16.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) TAF4 PF05236.14 EKX47900.1 - 0.052 13.3 14.2 0.066 13.0 14.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF4407 PF14362.6 EKX47900.1 - 8.4 5.7 8.1 11 5.3 8.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SUI1 PF01253.22 EKX47901.1 - 1.3e-23 83.3 4.5 1.6e-23 83.0 4.5 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 tRNA_int_endo PF01974.17 EKX47902.1 - 3.6e-18 65.4 0.0 6.1e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Glyco_hydro_2_C PF02836.17 EKX47903.1 - 5.3e-103 344.3 0.0 7.3e-103 343.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 EKX47903.1 - 4.9e-58 196.6 0.1 1.3e-57 195.2 0.0 1.8 2 0 0 2 2 2 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 EKX47903.1 - 4.1e-26 91.9 0.1 2.5e-25 89.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 EKX47903.1 - 1e-14 54.7 0.0 9.2e-14 51.7 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 EKX47903.1 - 2e-08 34.9 0.0 8e-08 32.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_72 PF03198.14 EKX47903.1 - 0.015 14.6 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Glucanosyltransferase Bax1-I PF01027.20 EKX47904.1 - 8.3e-35 120.5 43.9 9.4e-35 120.3 43.9 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 WD40 PF00400.32 EKX47905.1 - 1.5e-14 54.1 0.2 0.0088 16.9 0.1 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat WD40_like PF17005.5 EKX47905.1 - 6.8e-05 22.3 0.0 0.00029 20.3 0.0 1.8 1 1 1 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 EKX47905.1 - 0.038 14.3 0.1 3.1 8.1 0.0 2.8 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_7 PF13499.6 EKX47906.1 - 6.6e-13 48.9 6.7 1.1e-05 25.8 1.9 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX47906.1 - 2.4e-12 45.4 11.2 1.9e-06 27.0 0.5 3.8 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EKX47906.1 - 6.8e-11 41.8 3.8 1.3e-05 24.9 0.2 3.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX47906.1 - 1.5e-10 40.1 6.0 2.8e-06 26.8 0.1 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 EKX47906.1 - 1.6e-08 33.6 11.9 0.00033 20.0 0.3 3.7 3 0 0 3 3 3 2 EF hand TIR_2 PF13676.6 EKX47906.1 - 2.6e-08 34.5 0.0 8.1e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 TIR domain HTH_51 PF18558.1 EKX47906.1 - 0.16 11.8 0.0 22 5.0 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain Guanylate_cyc PF00211.20 EKX47908.1 - 3.4e-15 56.1 0.0 5e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Colipase_C PF02740.14 EKX47908.1 - 0.25 11.5 1.2 0.52 10.5 1.2 1.5 1 0 0 1 1 1 0 Colipase, C-terminal domain Ank_4 PF13637.6 EKX47909.1 - 6.1e-15 55.4 0.3 4.3e-10 39.9 0.0 3.7 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX47909.1 - 2.7e-12 46.6 0.7 2.1e-09 37.4 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX47909.1 - 1.7e-11 44.6 0.1 8.9e-11 42.2 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX47909.1 - 8.5e-07 28.8 0.1 0.007 16.8 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 EKX47909.1 - 3e-05 24.3 0.0 0.016 15.7 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat SAM_2 PF07647.17 EKX47909.1 - 0.0026 17.8 0.0 0.0066 16.5 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EKX47909.1 - 0.006 17.0 0.0 0.015 15.8 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) LNP1 PF15419.6 EKX47909.1 - 1.1 9.5 5.5 1.2 9.4 2.1 2.1 2 0 0 2 2 2 0 Leukemia NUP98 fusion partner 1 DUF4577 PF15145.6 EKX47910.1 - 0.07 13.2 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) PDZ_6 PF17820.1 EKX47911.1 - 1.3e-09 37.8 0.0 0.00072 19.4 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 EKX47911.1 - 2.9e-05 24.3 0.0 0.073 13.4 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX47911.1 - 0.00025 21.3 0.0 1.1 9.6 0.0 2.4 2 0 0 2 2 2 2 PDZ domain DFP PF04127.15 EKX47912.1 - 6.9e-21 74.9 0.0 7.6e-13 48.7 0.0 2.0 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein hnRNP_Q_AcD PF18360.1 EKX47913.1 - 5.6e-06 26.2 0.0 1.2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain FtsJ PF01728.19 EKX47913.1 - 0.00063 19.9 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF1824 PF08854.10 EKX47915.1 - 9.4e-06 25.6 0.0 0.00012 22.0 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1824) Phosphodiest PF01663.22 EKX47916.1 - 4.6e-13 49.5 0.8 2.2e-07 30.8 0.2 2.2 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 EKX47916.1 - 0.0078 15.6 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF2583 PF10762.9 EKX47917.1 - 0.00083 19.7 4.2 0.0014 19.0 0.3 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2583) T4SS_CagC PF16943.5 EKX47917.1 - 0.097 12.9 0.2 1.7 8.9 0.0 2.7 2 1 1 3 3 3 0 Cag pathogenicity island, type IV secretory system Esterase PF00756.20 EKX47918.1 - 0.0069 16.1 0.5 0.014 15.0 0.5 1.4 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EKX47918.1 - 0.071 12.6 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF3244 PF11589.8 EKX47918.1 - 0.17 12.0 0.1 0.43 10.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3244) Rubredoxin_2 PF18073.1 EKX47918.1 - 9.9 6.0 9.6 0.35 10.6 2.3 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain Kelch_5 PF13854.6 EKX47919.1 - 3.3e-14 52.5 0.0 0.0002 21.3 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 EKX47919.1 - 4.1e-14 52.3 0.3 0.003 17.5 0.0 4.4 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.6 EKX47919.1 - 3.5e-06 27.1 0.3 5.1 7.5 0.0 5.2 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 EKX47919.1 - 0.0004 20.2 3.0 7 6.8 0.0 4.4 4 1 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 EKX47919.1 - 0.00057 20.1 0.3 0.33 11.3 0.0 4.0 4 0 0 4 4 4 1 Kelch motif RAG2 PF03089.14 EKX47919.1 - 0.013 14.5 0.0 0.95 8.4 0.1 2.5 2 0 0 2 2 2 0 Recombination activating protein 2 HRXXH PF13933.6 EKX47919.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase family LNS2 PF08235.13 EKX47921.1 - 4.6e-30 104.8 0.0 7.1e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EKX47921.1 - 2.4e-08 33.9 0.0 4.2e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 lipin, N-terminal conserved region RNB PF00773.19 EKX47922.1 - 2.6e-48 165.0 2.9 5.1e-48 164.1 0.3 2.7 2 1 0 2 2 2 1 RNB domain HalOD1 PF18545.1 EKX47922.1 - 0.064 13.5 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 Halobacterial output domain 1 TetR_C_24 PF17932.1 EKX47923.1 - 0.88 9.8 4.7 4.7 7.5 0.2 3.0 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain MukB PF04310.12 EKX47923.1 - 8.6 6.1 6.5 4.1 7.1 0.4 2.1 1 1 1 2 2 2 0 MukB N-terminal Peptidase_M13_N PF05649.13 EKX47925.1 - 6.6e-76 256.5 0.0 9.7e-76 255.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 EKX47925.1 - 8.8e-56 188.7 0.0 1.6e-55 187.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M13 DUF5425 PF17472.2 EKX47925.1 - 4.4 8.2 7.0 0.29 12.0 1.3 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5425) ATPgrasp_ST PF14397.6 EKX47926.1 - 3.2e-05 23.3 0.0 0.012 14.9 0.0 2.1 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp RimK PF08443.11 EKX47926.1 - 0.23 11.0 0.0 12 5.4 0.0 2.1 2 0 0 2 2 2 0 RimK-like ATP-grasp domain CASP_C PF08172.12 EKX47927.1 - 2.6e-46 158.0 13.2 2.6e-46 158.0 13.2 4.4 2 1 2 4 4 4 1 CASP C terminal Sec2p PF06428.11 EKX47927.1 - 0.014 15.3 7.6 0.014 15.3 7.6 7.6 5 2 4 10 10 10 0 GDP/GTP exchange factor Sec2p DUF4200 PF13863.6 EKX47927.1 - 9.6 6.6 88.8 0.086 13.2 9.2 7.0 6 1 1 7 7 7 0 Domain of unknown function (DUF4200) Cellulase PF00150.18 EKX47928.1 - 8.9e-21 74.5 0.0 2e-20 73.4 0.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 EKX47928.1 - 1.7e-06 27.7 0.1 2.6e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 EKX47928.1 - 8.6e-05 22.3 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_53 PF07745.13 EKX47928.1 - 0.016 14.2 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 53 Glyco_hydro_2_C PF02836.17 EKX47928.1 - 0.099 11.7 0.0 0.29 10.2 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, TIM barrel domain LRR_6 PF13516.6 EKX47929.1 - 3.8e-18 63.9 41.9 0.002 18.1 0.3 10.7 12 0 0 12 12 12 6 Leucine Rich repeat LRR_4 PF12799.7 EKX47929.1 - 8.5e-06 26.0 33.0 0.21 12.1 0.4 7.7 6 4 2 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX47929.1 - 0.00039 20.1 33.2 0.03 14.1 5.8 8.0 5 3 3 8 8 8 2 Leucine rich repeat LRR_1 PF00560.33 EKX47929.1 - 0.0028 18.0 25.7 0.37 11.5 0.4 8.4 8 1 0 8 8 8 2 Leucine Rich Repeat Pneumovirus_M2 PF06436.11 EKX47929.1 - 0.1 12.0 0.7 0.22 11.0 0.1 1.8 2 0 0 2 2 2 0 Pneumovirus matrix protein 2 (M2) Thioredoxin PF00085.20 EKX47930.1 - 3.3e-30 104.1 0.0 6.8e-14 51.7 0.0 3.8 4 1 1 5 5 5 2 Thioredoxin Thioredoxin_6 PF13848.6 EKX47930.1 - 1.8e-16 60.6 0.0 6.2e-12 45.8 0.0 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EKX47930.1 - 4.2e-05 23.6 0.0 0.05 13.8 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EKX47930.1 - 0.00026 21.4 0.0 0.39 11.2 0.0 4.2 3 2 1 4 4 4 1 Thioredoxin-like domain EF-hand_1 PF00036.32 EKX47931.1 - 3.9e-20 69.8 2.4 1e-06 27.8 0.2 3.7 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 EKX47931.1 - 1.7e-18 66.8 1.4 5e-13 49.3 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX47931.1 - 1.9e-18 64.7 1.2 1.8e-05 24.3 0.1 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 EKX47931.1 - 1.2e-17 62.6 1.8 9.1e-08 31.3 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EKX47931.1 - 8.5e-12 44.7 1.8 8.4e-05 22.3 0.2 3.3 2 1 1 3 3 3 2 EF-hand domain pair EFhand_Ca_insen PF08726.10 EKX47931.1 - 1.2e-05 25.3 0.0 0.021 14.9 0.1 2.3 2 0 0 2 2 2 2 Ca2+ insensitive EF hand SPARC_Ca_bdg PF10591.9 EKX47931.1 - 6.8e-05 23.1 0.0 0.00011 22.5 0.0 1.4 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 EKX47931.1 - 0.00029 21.7 0.1 0.0017 19.2 0.0 1.9 1 1 1 2 2 2 1 EF-hand domain Trigger_C PF05698.14 EKX47931.1 - 0.0033 17.4 0.0 0.0063 16.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial trigger factor protein (TF) C-terminus DUF5580 PF17743.1 EKX47931.1 - 0.011 14.3 0.0 0.014 14.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Dockerin_1 PF00404.18 EKX47931.1 - 0.055 13.7 0.0 2.3 8.5 0.0 2.7 3 0 0 3 3 3 0 Dockerin type I domain Caleosin PF05042.13 EKX47931.1 - 0.11 12.5 0.2 6.1 6.7 0.1 2.8 1 1 1 3 3 3 0 Caleosin related protein EF-hand_10 PF14788.6 EKX47931.1 - 0.36 10.7 2.3 0.71 9.8 0.3 2.5 2 1 1 3 3 3 0 EF hand Pkinase PF00069.25 EKX47932.1 - 2.6e-76 256.5 0.0 3e-76 256.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX47932.1 - 8e-36 123.6 0.0 1e-35 123.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX47932.1 - 0.0006 19.2 0.0 0.0033 16.8 0.0 2.0 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 EKX47932.1 - 0.0011 18.6 0.1 0.0016 18.1 0.1 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EKX47932.1 - 0.0035 17.3 0.7 0.072 13.0 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX47932.1 - 0.0039 16.6 0.1 0.0073 15.7 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EKX47932.1 - 0.0092 15.6 0.0 0.87 9.2 0.0 2.1 1 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EKX47932.1 - 0.06 12.3 0.1 0.098 11.6 0.1 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EKX47932.1 - 0.14 10.9 0.0 0.27 10.0 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase TraB PF01963.17 EKX47934.1 - 4e-08 33.5 0.0 4.7e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 TraB family TetR_C_22 PF17928.1 EKX47934.1 - 0.083 13.2 0.1 3.6 7.9 0.0 2.6 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Glyco_transf_41 PF13844.6 EKX47935.1 - 1.1e-99 334.1 0.2 5.1e-50 170.3 0.1 2.0 1 1 1 2 2 2 2 Glycosyl transferase family 41 Spo12 PF05032.12 EKX47935.1 - 0.089 12.7 0.8 1.2 9.1 0.2 2.3 2 0 0 2 2 2 0 Spo12 family Collagen PF01391.18 EKX47936.1 - 1.3e-08 34.4 23.2 2e-08 33.9 23.2 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Cnn_1N PF07989.11 EKX47936.1 - 0.0025 17.9 0.2 0.007 16.5 0.0 1.8 2 0 0 2 2 2 1 Centrosomin N-terminal motif 1 DUF5527 PF17665.1 EKX47936.1 - 0.038 13.5 0.1 0.068 12.7 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5527) FliJ PF02050.16 EKX47936.1 - 0.055 13.7 0.1 0.13 12.5 0.0 1.6 1 1 0 1 1 1 0 Flagellar FliJ protein DUF724 PF05266.14 EKX47936.1 - 0.21 11.4 1.5 0.35 10.7 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) PTRF_SDPR PF15237.6 EKX47936.1 - 2 7.9 12.7 0.22 11.1 1.7 2.4 2 1 1 3 3 3 0 PTRF/SDPR family CLZ PF16526.5 EKX47936.1 - 2.7 8.4 5.8 7.9 6.9 0.3 3.1 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3671 PF12420.8 EKX47937.1 - 0.27 11.3 2.0 10 6.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function APG6_N PF17675.1 EKX47938.1 - 0.006 17.1 11.0 0.0085 16.6 11.0 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region CENP-H PF05837.12 EKX47938.1 - 0.012 16.0 10.0 0.012 16.0 10.0 1.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF4298 PF14131.6 EKX47938.1 - 0.034 14.1 4.1 0.06 13.3 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) HAUS6_N PF14661.6 EKX47938.1 - 0.19 11.3 6.3 0.22 11.1 6.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Methyltransf_31 PF13847.6 EKX47938.1 - 0.24 11.2 2.5 0.31 10.8 2.5 1.1 1 0 0 1 1 1 0 Methyltransferase domain DivIC PF04977.15 EKX47938.1 - 0.7 9.7 10.0 1.7 8.5 10.1 1.6 1 1 0 1 1 1 0 Septum formation initiator UPF0242 PF06785.11 EKX47938.1 - 1.1 9.4 15.5 1.6 8.8 15.2 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PX PF00787.24 EKX47939.1 - 4.4e-11 42.8 0.1 6.2e-11 42.3 0.1 1.1 1 0 0 1 1 1 1 PX domain APG6_N PF17675.1 EKX47939.1 - 0.1 13.2 0.2 0.18 12.3 0.1 1.5 2 0 0 2 2 2 0 Apg6 coiled-coil region Proteasom_PSMB PF10508.9 EKX47942.1 - 9.1e-32 110.2 3.8 1.1e-30 106.7 3.8 1.9 1 1 0 1 1 1 1 Proteasome non-ATPase 26S subunit Cnd1 PF12717.7 EKX47942.1 - 0.00039 20.5 0.8 0.0067 16.5 0.1 2.8 1 1 2 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Neurochondrin PF05536.11 EKX47942.1 - 0.0014 17.1 0.1 0.079 11.3 0.0 2.7 3 0 0 3 3 3 1 Neurochondrin HEAT PF02985.22 EKX47942.1 - 0.029 14.6 0.3 90 3.8 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat Cu_bind_like PF02298.17 EKX47942.1 - 0.21 11.6 0.0 0.41 10.7 0.0 1.4 1 0 0 1 1 1 0 Plastocyanin-like domain Ribosomal_60s PF00428.19 EKX47943.1 - 1.6e-22 79.9 7.5 2.3e-22 79.4 7.5 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_60s PF00428.19 EKX47944.1 - 1.3e-22 80.2 7.5 1.8e-22 79.7 7.5 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein CK_II_beta PF01214.18 EKX47945.1 - 0.05 13.4 0.7 0.093 12.5 0.7 1.3 1 0 0 1 1 1 0 Casein kinase II regulatory subunit Troponin PF00992.20 EKX47946.1 - 0.1 12.9 1.6 2.4 8.5 0.1 2.1 1 1 1 2 2 2 0 Troponin IL10 PF00726.17 EKX47947.1 - 0.056 13.0 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 Interleukin 10 TAF8_C PF10406.9 EKX47948.1 - 0.076 13.6 5.1 0.56 10.8 5.1 2.0 1 1 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term RabGAP-TBC PF00566.18 EKX47949.1 - 8.9e-26 90.9 0.3 1.3e-25 90.3 0.3 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PPR_2 PF13041.6 EKX47950.1 - 1.1e-116 380.9 24.9 7.3e-17 61.3 0.1 14.3 7 3 8 15 15 15 13 PPR repeat family PPR_3 PF13812.6 EKX47950.1 - 3.6e-116 379.3 10.2 8.2e-25 86.7 0.0 11.5 6 4 4 11 11 11 11 Pentatricopeptide repeat domain PPR PF01535.20 EKX47950.1 - 1.1e-77 251.1 24.0 2e-06 27.6 0.0 17.1 17 0 0 17 17 17 12 PPR repeat PPR_1 PF12854.7 EKX47950.1 - 7e-69 227.2 16.3 4.6e-07 29.4 0.0 17.2 17 1 0 17 17 17 12 PPR repeat PPR_long PF17177.4 EKX47950.1 - 1e-56 191.6 20.0 6.2e-19 68.2 0.1 7.2 1 1 6 7 7 7 7 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EKX47950.1 - 8.9e-09 35.5 0.0 7 7.8 0.0 9.0 11 1 1 12 12 10 1 Tetratricopeptide repeat COX5A PF02284.16 EKX47950.1 - 1e-05 25.4 1.7 3 7.9 0.0 5.5 4 2 2 6 6 6 1 Cytochrome c oxidase subunit Va TPR_7 PF13176.6 EKX47950.1 - 1.6e-05 24.6 3.3 15 5.9 0.0 7.4 9 0 0 9 9 7 0 Tetratricopeptide repeat RPM2 PF08579.11 EKX47950.1 - 2.7e-05 24.6 7.3 1.7 9.0 0.4 6.6 4 3 4 8 8 8 1 Mitochondrial ribonuclease P subunit (RPM2) Clathrin PF00637.20 EKX47950.1 - 3.1e-05 23.9 0.4 7.6 6.4 0.1 5.9 5 2 0 5 5 5 1 Region in Clathrin and VPS TPR_12 PF13424.6 EKX47950.1 - 0.00073 19.8 1.3 80 3.6 0.0 7.4 9 2 0 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.28 EKX47950.1 - 0.0015 18.2 0.5 13 5.7 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat RabGAP-TBC PF00566.18 EKX47950.1 - 0.0035 17.0 0.7 1.9 8.1 0.0 4.4 3 2 1 4 4 4 1 Rab-GTPase-TBC domain GMP_synt_C PF00958.22 EKX47950.1 - 0.012 15.7 2.5 23 5.1 0.0 4.9 4 1 1 5 5 4 0 GMP synthase C terminal domain ANAPC3 PF12895.7 EKX47950.1 - 0.015 15.5 1.9 14 6.0 0.0 5.6 6 2 1 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 Prp18 PF02840.15 EKX47950.1 - 0.022 14.8 2.6 14 5.7 0.2 4.5 4 1 0 4 4 4 0 Prp18 domain Utp21 PF04192.12 EKX47950.1 - 0.028 13.9 0.0 8 5.9 0.0 3.3 3 1 0 3 3 3 0 Utp21 specific WD40 associated putative domain ECSIT PF06239.11 EKX47950.1 - 0.035 13.2 12.6 9.6 5.3 0.2 7.2 6 4 3 9 9 9 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_6 PF13174.6 EKX47950.1 - 0.063 13.9 0.5 92 4.0 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1884 PF08967.10 EKX47950.1 - 0.074 13.3 0.1 47 4.3 0.0 4.2 5 0 0 5 5 4 0 Domain of unknown function (DUF1884) MRP-S27 PF10037.9 EKX47950.1 - 0.085 11.7 6.7 16 4.2 0.0 4.7 4 1 1 5 5 5 0 Mitochondrial 28S ribosomal protein S27 Exog_C PF18026.1 EKX47950.1 - 0.27 11.3 1.4 7.4 6.7 0.1 3.7 5 0 0 5 5 3 0 Endo/exonuclease (EXOG) C-terminal domain FbpA PF05833.11 EKX47951.1 - 3.7e-23 82.0 6.7 2.1e-22 79.5 6.7 2.2 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 EKX47951.1 - 1.6e-15 57.7 0.1 1.3e-06 29.0 0.0 2.9 1 1 1 2 2 2 2 NFACT protein RNA binding domain NFACT-C PF11923.8 EKX47951.1 - 3.3e-08 33.4 0.0 3.3e-08 33.4 0.0 2.5 3 0 0 3 3 3 1 NFACT protein C-terminal domain Beta_helix PF13229.6 EKX47952.1 - 0.0019 18.0 0.0 0.0061 16.4 0.0 1.9 1 0 0 1 1 1 1 Right handed beta helix region DUF1451 PF07295.11 EKX47953.1 - 0.00061 19.9 0.4 0.00061 19.9 0.4 3.0 2 2 1 3 3 3 1 Zinc-ribbon containing domain Trm112p PF03966.16 EKX47953.1 - 0.011 16.3 0.2 0.061 13.9 0.2 2.3 1 1 0 1 1 1 0 Trm112p-like protein Prok-RING_1 PF14446.6 EKX47953.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 GP41 PF00517.17 EKX47953.1 - 0.45 10.4 3.5 0.29 11.0 0.4 2.1 2 0 0 2 2 2 0 Retroviral envelope protein CLU PF13236.6 EKX47954.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Clustered mitochondria P16-Arc PF04699.14 EKX47955.1 - 0.0084 16.6 0.4 0.011 16.2 0.4 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) PWWP PF00855.17 EKX47955.1 - 0.62 10.5 2.7 1.9 9.0 0.0 2.1 1 1 1 2 2 2 0 PWWP domain Ephrin_rec_like PF07699.13 EKX47956.1 - 6.1e-05 22.7 4.4 6.1e-05 22.7 4.4 3.8 3 1 1 4 4 4 1 Putative ephrin-receptor like NifZ PF04319.13 EKX47956.1 - 0.14 11.9 0.0 14 5.6 0.0 2.4 2 0 0 2 2 2 0 NifZ domain LysM PF01476.20 EKX47956.1 - 0.15 12.2 0.2 18 5.5 0.0 2.3 2 0 0 2 2 2 0 LysM domain RNase_H PF00075.24 EKX47956.1 - 0.15 12.3 0.1 16 5.6 0.0 2.4 2 0 0 2 2 2 0 RNase H UCH PF00443.29 EKX47957.1 - 9.6e-47 159.6 0.1 1.1e-46 159.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EKX47957.1 - 6.8e-15 55.5 1.6 3.2e-13 50.0 1.6 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.32 EKX47958.1 - 0.013 16.4 5.2 0.079 13.9 0.4 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat Nup160 PF11715.8 EKX47958.1 - 0.056 12.1 0.0 1.5 7.4 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 RCC1_2 PF13540.6 EKX47958.1 - 0.15 11.9 1.5 6.4 6.7 0.2 2.8 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat FKBP_C PF00254.28 EKX47959.1 - 9.4e-31 106.0 0.0 1.5e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Aldo_ket_red PF00248.21 EKX47960.1 - 1.2e-33 116.6 0.0 5.3e-31 107.9 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family LSDAT_euk PF18139.1 EKX47960.1 - 0.049 13.0 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 SLOG in TRPM SAM_1 PF00536.30 EKX47961.1 - 6.6e-13 48.9 0.0 1.1e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EKX47961.1 - 8.3e-11 41.8 0.0 2e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 EKX47961.1 - 0.1 12.7 0.4 0.9 9.7 0.1 2.4 2 0 0 2 2 2 0 IGR protein motif Pkinase PF00069.25 EKX47962.1 - 5.3e-42 144.0 0.0 2.5e-41 141.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX47962.1 - 2.6e-37 128.5 0.0 7.2e-37 127.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX47962.1 - 7.8e-07 28.2 0.0 2.3e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EKX47962.1 - 5.3e-05 23.3 0.0 8.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EKX47962.1 - 6.3e-05 22.4 0.0 0.00095 18.6 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EKX47962.1 - 0.00053 19.4 0.0 0.00077 18.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EKX47962.1 - 0.1 11.6 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 WD40 PF00400.32 EKX47963.1 - 1.6e-46 155.3 27.0 3.3e-09 37.2 0.5 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX47963.1 - 1.1e-25 89.8 5.6 7.7e-07 29.3 0.1 5.9 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EKX47963.1 - 2.7e-11 43.4 0.0 0.0037 16.6 0.0 3.8 2 1 2 4 4 4 3 WD40-like domain Ge1_WD40 PF16529.5 EKX47963.1 - 1e-06 27.9 0.5 0.63 8.9 0.0 4.0 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EKX47963.1 - 3.9e-05 22.5 1.7 0.031 12.9 0.5 3.6 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 EKX47963.1 - 5.4e-05 22.7 4.2 1.6 8.0 0.1 4.4 1 1 4 5 5 5 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 EKX47963.1 - 0.00084 19.2 0.1 2.3 8.3 0.0 3.9 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat DUF3047 PF11249.8 EKX47963.1 - 0.0022 17.4 0.2 5.3 6.4 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3047) IKI3 PF04762.12 EKX47963.1 - 0.01 13.9 0.6 0.57 8.1 1.0 2.6 1 1 1 2 2 2 0 IKI3 family Gag_p10 PF02337.17 EKX47963.1 - 0.14 12.2 0.2 37 4.4 0.0 3.0 3 0 0 3 3 3 0 Retroviral GAG p10 protein Coatomer_WDAD PF04053.14 EKX47963.1 - 0.27 10.2 0.0 2.2 7.3 0.0 2.1 1 1 2 3 3 3 0 Coatomer WD associated region Aim19 PF10315.9 EKX47963.1 - 0.7 10.2 5.0 19 5.6 0.3 2.7 3 0 0 3 3 3 0 Altered inheritance of mitochondria protein 19 DUF374 PF04028.13 EKX47963.1 - 0.71 9.5 9.2 5.7 6.6 0.4 3.7 2 1 2 4 4 4 0 Domain of unknown function (DUF374) Meleagrin PF08189.11 EKX47963.1 - 0.72 9.6 4.3 28 4.5 0.0 3.7 4 0 0 4 4 4 0 Meleagrin/Cygnin family WD40 PF00400.32 EKX47964.1 - 3.1e-66 217.7 46.0 1.9e-11 44.3 1.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX47964.1 - 5.4e-30 103.5 17.5 5.9e-09 36.1 0.1 6.8 1 1 6 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX47964.1 - 1.6e-11 43.7 2.5 0.082 11.9 0.0 5.7 1 1 5 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EKX47964.1 - 6.7e-11 42.4 5.6 4.6e-06 26.6 0.1 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EKX47964.1 - 1.8e-08 34.1 0.0 0.00077 18.9 0.0 3.9 1 1 2 3 3 3 2 WD40-like domain Nup160 PF11715.8 EKX47964.1 - 4.7e-07 28.8 11.0 0.074 11.7 0.2 5.5 1 1 5 6 6 6 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EKX47964.1 - 2.3e-05 23.1 1.1 0.0031 16.1 0.2 2.9 1 1 1 3 3 3 2 Cytochrome D1 heme domain VID27 PF08553.10 EKX47964.1 - 0.00012 21.3 0.1 0.37 9.8 0.0 2.3 1 1 1 2 2 2 2 VID27 C-terminal WD40-like domain Coatomer_WDAD PF04053.14 EKX47964.1 - 0.00064 18.9 0.6 0.0017 17.5 0.4 1.8 1 1 0 1 1 1 1 Coatomer WD associated region Me-amine-dh_H PF06433.11 EKX47964.1 - 0.00072 18.5 0.0 0.54 9.1 0.0 3.0 1 1 1 3 3 3 2 Methylamine dehydrogenase heavy chain (MADH) PD40 PF07676.12 EKX47964.1 - 0.00092 19.1 11.3 0.98 9.4 0.2 5.8 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat IKI3 PF04762.12 EKX47964.1 - 0.0066 14.5 13.3 0.014 13.5 2.5 2.3 1 1 1 2 2 2 2 IKI3 family Ribosomal_L21e PF01157.18 EKX47964.1 - 0.026 14.4 0.0 3.4 7.6 0.0 3.5 4 1 0 4 4 4 0 Ribosomal protein L21e TFIIIC_delta PF12657.7 EKX47964.1 - 7 6.5 20.0 0.33 10.9 1.9 4.1 4 1 0 4 4 4 0 Transcription factor IIIC subunit delta N-term Pkinase PF00069.25 EKX47965.1 - 8.2e-36 123.7 0.0 9.2e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX47965.1 - 8.8e-32 110.4 0.0 9.9e-32 110.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX47965.1 - 3.3e-05 22.8 0.0 5.7e-05 22.1 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EKX47965.1 - 0.0002 21.4 0.0 0.00024 21.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX47965.1 - 0.00062 19.2 0.0 0.00086 18.7 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EKX47965.1 - 0.0025 17.2 0.0 0.0083 15.5 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EKX47965.1 - 0.038 13.0 0.0 0.053 12.6 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 EKX47965.1 - 0.18 11.4 0.1 0.36 10.4 0.1 1.7 1 1 0 1 1 1 0 RIO1 family Pkinase PF00069.25 EKX47966.1 - 8.2e-36 123.7 0.0 9.2e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX47966.1 - 8.8e-32 110.4 0.0 9.9e-32 110.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX47966.1 - 3.3e-05 22.8 0.0 5.7e-05 22.1 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EKX47966.1 - 0.0002 21.4 0.0 0.00024 21.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX47966.1 - 0.00062 19.2 0.0 0.00086 18.7 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EKX47966.1 - 0.0025 17.2 0.0 0.0083 15.5 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EKX47966.1 - 0.038 13.0 0.0 0.053 12.6 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 EKX47966.1 - 0.18 11.4 0.1 0.36 10.4 0.1 1.7 1 1 0 1 1 1 0 RIO1 family WD40 PF00400.32 EKX47967.1 - 1.4e-61 203.0 36.8 1e-09 38.8 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX47967.1 - 3.2e-30 104.3 11.2 1.5e-06 28.4 0.4 6.9 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX47967.1 - 3.1e-10 39.5 2.2 0.035 13.1 0.0 5.8 1 1 5 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EKX47967.1 - 7.7e-10 38.0 8.5 0.17 10.5 0.0 5.9 1 1 5 6 6 6 4 Nucleoporin Nup120/160 eIF2A PF08662.11 EKX47967.1 - 1e-09 38.6 2.4 2.1e-06 27.8 0.2 3.2 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 EKX47967.1 - 4.5e-07 28.3 6.6 0.00029 19.0 0.7 2.2 1 1 1 2 2 2 2 IKI3 family PD40 PF07676.12 EKX47967.1 - 1.1e-06 28.4 2.8 1.3 9.0 0.2 5.1 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat WD40_like PF17005.5 EKX47967.1 - 3.8e-06 26.4 0.2 0.54 9.5 0.0 4.1 2 2 2 4 4 4 2 WD40-like domain Me-amine-dh_H PF06433.11 EKX47967.1 - 5.3e-05 22.3 0.0 6.8 5.4 0.0 4.0 2 2 2 4 4 4 2 Methylamine dehydrogenase heavy chain (MADH) Mid2 PF04478.12 EKX47967.1 - 0.0059 16.4 2.8 0.65 9.8 0.1 3.8 2 1 1 4 4 4 1 Mid2 like cell wall stress sensor DUF5570 PF17731.1 EKX47967.1 - 0.0081 16.2 11.0 0.036 14.2 0.3 4.0 2 2 3 5 5 5 1 Family of unknown function (DUF5570) PQQ_3 PF13570.6 EKX47967.1 - 0.017 15.6 0.1 9.2 6.9 0.0 3.9 3 1 1 4 4 4 0 PQQ-like domain VID27 PF08553.10 EKX47967.1 - 0.15 11.1 0.0 10 5.1 0.0 2.8 1 1 1 2 2 2 0 VID27 C-terminal WD40-like domain Resistin PF06954.11 EKX47967.1 - 1.2 9.8 5.6 0.2 12.2 0.4 2.5 2 1 0 2 2 2 0 Resistin Pkinase PF00069.25 EKX47969.1 - 3.1e-33 115.3 0.0 1.6e-32 112.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX47969.1 - 1.9e-30 106.0 0.0 5.7e-30 104.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX47969.1 - 2.2e-06 26.7 0.0 3.9e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EKX47969.1 - 0.00047 19.6 0.0 0.00076 18.9 0.0 1.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EKX47969.1 - 0.00053 20.0 0.0 0.00079 19.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX47969.1 - 0.0012 18.3 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EKX47969.1 - 0.017 14.2 0.0 0.023 13.7 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 WD40 PF00400.32 EKX47970.1 - 5.8e-46 153.5 33.2 8.2e-10 39.1 1.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX47970.1 - 4.2e-24 84.7 5.6 4.2e-05 23.8 0.0 5.6 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX47970.1 - 6.2e-12 45.1 2.8 0.027 13.4 0.1 4.7 1 1 2 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EKX47970.1 - 2.5e-08 33.6 0.2 0.004 16.5 0.0 3.3 1 1 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 EKX47970.1 - 6.2e-05 21.8 1.3 1.7 7.2 0.0 5.0 1 1 5 6 6 6 1 Nucleoporin Nup120/160 PQQ_3 PF13570.6 EKX47970.1 - 0.00011 22.6 0.9 22 5.7 0.0 5.7 6 1 0 6 6 6 0 PQQ-like domain PD40 PF07676.12 EKX47970.1 - 0.00014 21.6 0.0 0.028 14.4 0.0 3.9 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat DUF5122 PF17164.4 EKX47970.1 - 0.00086 19.5 1.2 8.4 6.8 0.0 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF5122) beta-propeller DUF374 PF04028.13 EKX47970.1 - 0.005 16.4 7.9 0.65 9.6 0.4 4.2 2 2 2 4 4 4 1 Domain of unknown function (DUF374) Ret2_MD PF18528.1 EKX47970.1 - 0.015 15.7 0.0 24 5.4 0.0 3.1 2 1 1 3 3 3 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Meleagrin PF08189.11 EKX47970.1 - 0.11 12.2 21.4 13 5.6 0.1 5.6 5 0 0 5 5 5 0 Meleagrin/Cygnin family Pox_TAP PF03355.14 EKX47970.1 - 0.12 11.9 1.6 1.6 8.2 0.1 2.0 2 0 0 2 2 2 0 Viral Trans-Activator Protein NusG_II PF07009.11 EKX47970.1 - 0.2 11.9 13.2 3.9 7.7 0.3 4.2 2 2 3 5 5 5 0 NusG domain II Agouti PF05039.12 EKX47970.1 - 2.1 9.1 15.3 66 4.3 0.1 5.0 5 0 0 5 5 5 0 Agouti protein DUF4797 PF16051.5 EKX47970.1 - 4.7 7.2 7.9 78 3.3 0.1 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF4797) O-FucT PF10250.9 EKX47971.1 - 1.6e-07 31.4 0.0 2.8e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF4625 PF15418.6 EKX47971.1 - 0.0019 18.4 0.0 0.15 12.3 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4625) Glyco_transf_11 PF01531.16 EKX47971.1 - 0.0094 15.2 0.2 0.15 11.2 0.2 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 11 HEAT_2 PF13646.6 EKX47972.1 - 2.3e-09 37.5 2.8 5.6e-05 23.5 0.1 3.2 1 1 2 3 3 3 2 HEAT repeats HEAT PF02985.22 EKX47972.1 - 3.7e-06 26.7 0.1 2.4 8.7 0.0 3.5 3 0 0 3 3 3 3 HEAT repeat Cnd1 PF12717.7 EKX47972.1 - 0.028 14.5 0.0 0.079 13.0 0.0 1.7 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Bax1-I PF01027.20 EKX47973.1 - 7e-26 91.3 7.8 1.1e-25 90.8 7.8 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 SirB PF04247.12 EKX47973.1 - 0.035 14.2 1.3 0.035 14.2 1.3 2.0 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB Linker_histone PF00538.19 EKX47974.1 - 0.023 15.1 3.1 0.33 11.3 0.9 3.1 2 0 0 2 2 2 0 linker histone H1 and H5 family DUF948 PF06103.11 EKX47974.1 - 0.23 11.8 0.1 0.23 11.8 0.1 4.1 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF2951 PF11166.8 EKX47974.1 - 0.37 11.0 10.9 0.4 10.9 0.9 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Cep57_CLD_2 PF14197.6 EKX47974.1 - 7.9 6.6 13.3 1.5 9.0 2.1 4.0 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 TTL PF03133.15 EKX47977.1 - 3e-16 59.4 1.7 1.1e-15 57.6 0.1 2.6 2 1 0 2 2 2 1 Tubulin-tyrosine ligase family NLPC_P60 PF00877.19 EKX47977.1 - 0.00069 19.6 0.0 0.0023 17.9 0.0 1.8 1 0 0 1 1 1 1 NlpC/P60 family BTB PF00651.31 EKX47978.1 - 4e-16 59.2 0.0 7.7e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 EKX47978.1 - 3.2e-10 40.0 0.1 1.3e-09 38.1 0.0 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch DUF3342 PF11822.8 EKX47978.1 - 5.1e-07 29.8 0.0 1.4e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) PDZ_2 PF13180.6 EKX47978.1 - 0.0016 18.7 0.0 0.003 17.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain BTB_2 PF02214.22 EKX47978.1 - 0.016 15.5 0.0 0.049 14.0 0.0 1.9 1 1 0 1 1 1 0 BTB/POZ domain Tricorn_PDZ PF14685.6 EKX47978.1 - 0.093 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain RRF PF01765.19 EKX47978.1 - 0.14 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Ribosome recycling factor Collagen PF01391.18 EKX47979.1 - 9.2e-15 54.2 60.9 1.4e-08 34.4 28.5 2.4 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) PocR PF10114.9 EKX47979.1 - 0.089 12.6 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Sensory domain found in PocR FapA PF03961.13 EKX47979.1 - 2 6.9 6.8 2.8 6.5 6.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A PDZ_6 PF17820.1 EKX47980.1 - 4.1e-05 23.3 0.1 7.8e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX47980.1 - 9.7e-05 22.7 0.2 0.0002 21.6 0.2 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX47980.1 - 0.0052 17.1 0.1 0.011 16.0 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX47980.1 - 0.1 12.5 0.0 1 9.3 0.0 2.2 2 0 0 2 2 2 0 Tricorn protease PDZ domain UPF0020 PF01170.18 EKX47981.1 - 1.9e-35 122.3 0.0 5.1e-35 121.0 0.0 1.7 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 EKX47981.1 - 4.4e-10 39.6 0.1 3.9e-08 33.2 0.0 3.0 2 1 1 3 3 3 1 Methyltransferase domain MTS PF05175.14 EKX47981.1 - 1.7e-08 34.2 0.0 3.5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EKX47981.1 - 4.2e-06 27.4 0.0 5.1e-05 23.9 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX47981.1 - 9.6e-05 23.0 0.2 0.0015 19.2 0.1 3.1 4 1 0 4 4 4 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EKX47981.1 - 0.00011 21.9 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 N6_Mtase PF02384.16 EKX47981.1 - 0.0013 18.1 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase THUMP PF02926.17 EKX47981.1 - 0.0019 18.3 0.0 0.0049 17.0 0.0 1.7 1 0 0 1 1 1 1 THUMP domain Methyltransf_15 PF09445.10 EKX47981.1 - 0.031 13.8 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_12 PF08242.12 EKX47981.1 - 0.064 14.0 0.0 1.1 10.1 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase domain Glyco_transf_10 PF00852.19 EKX47983.1 - 5e-30 104.5 0.0 7.4e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term SET PF00856.28 EKX47985.1 - 3.6e-18 66.5 0.2 2e-17 64.1 0.2 1.8 1 1 0 1 1 1 1 SET domain GpcrRhopsn4 PF10192.9 EKX47987.1 - 6.7e-36 124.0 9.6 9e-36 123.6 9.6 1.2 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 EKX47987.1 - 4.3e-06 26.2 6.2 6.3e-06 25.6 6.2 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor CCDC-167 PF15188.6 EKX47987.1 - 3.6 8.0 4.0 1 9.8 0.4 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 SHE3 PF17078.5 EKX47988.1 - 0.0012 18.6 17.4 0.0012 18.6 17.4 2.5 2 0 0 2 2 2 1 SWI5-dependent HO expression protein 3 ATG16 PF08614.11 EKX47988.1 - 0.27 11.4 40.1 0.053 13.7 17.6 3.8 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) Mod_r PF07200.13 EKX47988.1 - 2.5 8.2 44.2 0.29 11.2 7.1 3.8 2 1 2 4 4 4 0 Modifier of rudimentary (Mod(r)) protein DUF563 PF04577.14 EKX47989.1 - 2.9e-15 57.0 0.0 6.6e-15 55.8 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF563) YflT PF11181.8 EKX47989.1 - 0.15 12.6 2.9 0.21 12.1 0.0 2.6 3 0 0 3 3 3 0 Heat induced stress protein YflT EFTUD2 PF16004.5 EKX47989.1 - 5.6 7.6 8.5 1.3 9.6 0.6 2.5 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Ribosomal_L28e PF01778.17 EKX47990.1 - 1.8e-31 109.3 1.3 2.1e-31 109.0 1.3 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family FhuF_C PF11575.8 EKX47992.1 - 0.051 13.5 39.1 7.2 6.6 0.9 6.1 6 0 0 6 6 6 0 FhuF 2Fe-2S C-terminal domain Kinesin PF00225.23 EKX47993.1 - 2.5e-34 118.7 0.0 3e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX47993.1 - 4e-29 101.5 0.1 4.5e-29 101.3 0.1 1.0 1 0 0 1 1 1 1 Microtubule binding Bac_DnaA PF00308.18 EKX47993.1 - 0.024 14.5 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial dnaA protein IstB_IS21 PF01695.17 EKX47993.1 - 0.043 13.5 0.0 0.058 13.1 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase_2 PF01637.18 EKX47993.1 - 0.076 12.9 0.0 0.15 12.0 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EKX47993.1 - 0.1 12.3 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EKX47993.1 - 0.18 11.5 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Beta_helix PF13229.6 EKX47994.1 - 3.8e-07 30.1 0.0 1.4e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Right handed beta helix region Adeno_E1B_55K PF01696.17 EKX47994.1 - 0.012 14.3 1.8 0.026 13.2 1.8 1.5 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen NosD PF05048.13 EKX47994.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) PIH1_CS PF18201.1 EKX47996.1 - 8.6e-12 45.3 0.1 3.2e-11 43.5 0.1 2.0 2 0 0 2 2 2 1 PIH1 CS-like domain UVR PF02151.19 EKX47997.1 - 0.012 15.4 1.6 0.012 15.4 1.6 2.6 3 0 0 3 3 3 0 UvrB/uvrC motif SbcD_C PF12320.8 EKX47997.1 - 1.3 9.3 4.7 0.55 10.6 0.1 2.8 3 0 0 3 3 3 0 Type 5 capsule protein repressor C-terminal domain APG6_N PF17675.1 EKX47998.1 - 2 8.9 19.2 0.13 12.8 10.9 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region C2 PF00168.30 EKX47999.1 - 7.9e-06 26.1 0.0 1.5e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain Met_10 PF02475.16 EKX48000.1 - 3e-50 170.7 0.0 3e-34 118.5 0.0 2.3 2 0 0 2 2 2 2 Met-10+ like-protein TRM PF02005.16 EKX48000.1 - 0.026 13.7 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase PrmA PF06325.13 EKX48000.1 - 0.17 11.2 0.0 0.39 10.1 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) IGFBP PF00219.18 EKX48000.1 - 9 7.0 8.9 8.2 7.2 2.2 2.6 2 0 0 2 2 2 0 Insulin-like growth factor binding protein RskA PF10099.9 EKX48002.1 - 0.0099 16.2 1.8 0.017 15.4 1.8 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA 60KD_IMP PF02096.20 EKX48002.1 - 0.014 15.3 10.3 5.3 6.9 0.0 2.3 2 0 0 2 2 2 0 60Kd inner membrane protein SUIM_assoc PF16619.5 EKX48002.1 - 0.016 15.2 17.6 39 4.4 17.6 2.6 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 NPR1_interact PF15699.5 EKX48002.1 - 0.022 15.4 13.0 1.2 9.8 4.5 3.2 3 0 0 3 3 3 0 NPR1 interacting PEPcase_2 PF14010.6 EKX48002.1 - 0.037 12.5 0.0 0.037 12.5 0.0 1.3 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxylase Suf PF05843.14 EKX48002.1 - 0.048 13.6 6.3 0.081 12.9 6.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4834 PF16118.5 EKX48002.1 - 0.054 14.5 7.0 0.079 13.9 5.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) CAF1 PF04857.20 EKX48002.1 - 0.095 11.8 4.6 0.13 11.4 4.7 1.3 1 1 0 1 1 1 0 CAF1 family ribonuclease Presenilin PF01080.17 EKX48002.1 - 0.11 11.3 1.9 0.17 10.7 1.9 1.4 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 EKX48002.1 - 0.17 11.6 0.5 0.29 10.8 0.5 1.4 1 0 0 1 1 1 0 Connexin Renin_r PF07850.14 EKX48002.1 - 0.18 12.4 0.2 0.47 11.1 0.2 1.7 1 0 0 1 1 1 0 Renin receptor-like protein DUF4094 PF13334.6 EKX48002.1 - 0.2 12.1 6.3 0.61 10.5 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) AAA_23 PF13476.6 EKX48002.1 - 0.25 11.8 10.8 9.9 6.6 7.7 2.2 2 0 0 2 2 2 0 AAA domain OATP PF03137.20 EKX48002.1 - 0.32 9.2 1.8 0.55 8.5 1.8 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family EOS1 PF12326.8 EKX48002.1 - 0.48 10.3 1.9 0.72 9.8 1.8 1.5 1 1 0 1 1 1 0 N-glycosylation protein DUF724 PF05266.14 EKX48002.1 - 0.63 9.8 10.3 0.16 11.8 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) MTABC_N PF16185.5 EKX48002.1 - 0.76 9.2 1.9 0.86 9.0 0.6 1.7 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region DUF3464 PF11947.8 EKX48002.1 - 1.1 9.0 6.7 2.4 7.9 6.7 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 TFIIA PF03153.13 EKX48002.1 - 1.7 8.5 18.4 0.23 11.4 14.6 1.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 EKX48002.1 - 5.4 6.6 25.5 2.7 7.5 23.2 1.6 2 0 0 2 2 2 0 Spt20 family SNF2_N PF00176.23 EKX48003.1 - 9e-64 215.4 0.3 1.7e-63 214.4 0.3 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX48003.1 - 1e-19 70.9 0.0 6.9e-19 68.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EKX48003.1 - 1.2e-08 34.5 0.1 1.6e-06 27.5 0.1 2.2 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 EKX48003.1 - 1.6e-07 31.3 0.0 3.1e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EKX48003.1 - 1.1e-05 25.5 0.0 2.3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EKX48003.1 - 0.00023 20.9 0.0 0.00042 20.1 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_34 PF13872.6 EKX48003.1 - 0.023 13.6 0.0 0.065 12.1 0.0 1.7 1 1 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 HECT PF00632.25 EKX48004.1 - 3.7e-07 29.9 0.0 0.00011 21.8 0.0 2.2 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) DnaJ_C PF01556.18 EKX48005.1 - 2.6e-40 137.9 0.8 3.4e-40 137.5 0.8 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EKX48005.1 - 1.4e-26 92.4 4.2 2.2e-26 91.8 4.2 1.3 1 0 0 1 1 1 1 DnaJ domain FAD_binding_3 PF01494.19 EKX48006.1 - 1.1e-26 94.0 0.4 4.6e-26 91.9 0.4 1.9 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 EKX48006.1 - 9.9e-05 21.5 0.0 0.057 12.5 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase Trp_halogenase PF04820.14 EKX48006.1 - 0.00027 19.9 1.6 0.1 11.4 0.5 3.1 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_8 PF13450.6 EKX48006.1 - 0.00027 21.1 0.2 0.00062 19.9 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EKX48006.1 - 0.0005 19.2 0.1 0.06 12.4 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 EKX48006.1 - 0.001 19.1 0.1 0.0041 17.1 0.2 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EKX48006.1 - 0.0066 15.7 0.4 0.022 14.0 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EKX48006.1 - 0.0069 16.9 0.1 0.026 15.1 0.1 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EKX48006.1 - 0.011 15.0 0.1 0.016 14.5 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EKX48006.1 - 0.011 15.3 0.4 0.02 14.5 0.3 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 EKX48006.1 - 0.027 13.7 1.5 0.064 12.5 1.5 1.7 1 1 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 EKX48006.1 - 0.068 11.9 0.6 0.093 11.4 0.6 1.1 1 0 0 1 1 1 0 HI0933-like protein Peptidase_M16_M PF16187.5 EKX48009.1 - 2.5e-66 223.8 0.0 3.6e-66 223.3 0.0 1.2 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EKX48009.1 - 8.7e-31 106.9 0.0 1.8e-30 105.9 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EKX48009.1 - 2e-29 102.9 0.0 5.5e-18 65.6 0.0 3.3 3 0 0 3 3 3 2 Peptidase M16 inactive domain AMPK1_CBM PF16561.5 EKX48010.1 - 1.4e-15 57.3 0.2 3e-15 56.2 0.2 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase YfdX PF10938.8 EKX48010.1 - 1.6e-09 37.9 44.4 0.037 14.0 1.6 6.8 7 1 0 7 7 7 5 YfdX protein Ribonuc_L-PSP PF01042.21 EKX48010.1 - 5.1e-05 23.3 22.4 2 8.5 0.2 5.9 5 0 0 5 5 5 5 Endoribonuclease L-PSP DUF2564 PF10819.8 EKX48010.1 - 5.1e-05 23.6 51.0 0.3 11.5 1.2 6.9 6 0 0 6 6 6 5 Protein of unknown function (DUF2564) EF-hand_1 PF00036.32 EKX48010.1 - 5.6e-05 22.4 0.2 0.0017 17.8 0.2 3.4 2 0 0 2 2 2 1 EF hand Lambda_Kil PF06301.11 EKX48010.1 - 0.00012 21.6 21.8 2.2 7.9 0.3 5.6 5 0 0 5 5 5 4 Bacteriophage lambda Kil protein EF-hand_6 PF13405.6 EKX48010.1 - 0.00021 21.0 0.1 0.0035 17.2 0.1 3.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 EKX48010.1 - 0.0018 17.7 0.1 0.0062 16.0 0.1 2.0 1 0 0 1 1 1 1 EF hand Spore_YpjB PF09577.10 EKX48010.1 - 0.019 14.8 34.9 1.4 8.7 0.7 5.9 5 0 0 5 5 5 0 Sporulation protein YpjB (SpoYpjB) PTS_IIA PF02255.16 EKX48010.1 - 0.022 14.8 61.6 0.16 12.0 1.6 8.2 7 2 1 8 8 8 0 PTS system, Lactose/Cellobiose specific IIA subunit TPR_19 PF14559.6 EKX48010.1 - 0.062 13.8 33.1 13 6.3 0.0 7.5 7 0 0 7 7 7 0 Tetratricopeptide repeat EF-hand_7 PF13499.6 EKX48010.1 - 0.088 13.3 0.0 0.088 13.3 0.0 6.9 6 1 1 7 7 7 0 EF-hand domain pair DUF1911 PF08929.10 EKX48010.1 - 0.49 11.2 20.1 25 5.7 0.3 5.3 5 0 0 5 5 5 0 Domain of unknown function (DUF1911) Imm51 PF15595.6 EKX48010.1 - 0.65 10.0 21.8 35 4.4 0.3 6.1 5 0 0 5 5 5 0 Immunity protein 51 Mg_trans_NIPA PF05653.14 EKX48011.1 - 8.6e-29 100.6 10.5 1.3e-28 100.0 8.7 1.8 1 1 1 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 EKX48011.1 - 0.0048 17.1 0.9 0.0048 17.1 0.9 3.1 3 1 1 4 4 4 1 EamA-like transporter family Phage_FRD3 PF05798.11 EKX48012.1 - 0.044 14.1 0.0 0.066 13.5 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage FRD3 protein Inhibitor_I42 PF09394.10 EKX48013.1 - 3.8e-19 68.9 0.1 4.9e-19 68.5 0.1 1.2 1 0 0 1 1 1 1 Chagasin family peptidase inhibitor I42 Inhibitor_I71 PF12628.7 EKX48013.1 - 0.00038 20.4 0.0 0.63 9.9 0.0 2.1 1 1 1 2 2 2 2 Falstatin, cysteine peptidase inhibitor Glycos_transf_2 PF00535.26 EKX48014.1 - 1.3e-16 60.9 0.1 3e-16 59.7 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EKX48014.1 - 2.6e-07 30.7 0.1 4.3e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EKX48014.1 - 0.011 16.3 1.4 0.019 15.5 0.5 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 2 FKBP_C PF00254.28 EKX48016.1 - 5.5e-63 209.3 0.1 6.8e-32 109.7 0.0 3.4 3 0 0 3 3 3 3 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 EKX48016.1 - 1.2e-17 62.9 0.5 2.2e-06 27.2 0.0 3.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX48016.1 - 1e-15 56.5 0.1 3.4e-05 23.6 0.0 3.7 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX48016.1 - 1e-12 47.5 0.1 0.001 18.7 0.1 3.9 2 1 1 3 3 3 3 TPR repeat TPR_12 PF13424.6 EKX48016.1 - 1.3e-08 35.0 0.1 0.00038 20.7 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX48016.1 - 2e-07 30.6 1.7 0.036 14.3 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX48016.1 - 1.5e-06 28.1 0.1 0.00077 19.7 0.0 3.1 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX48016.1 - 9.4e-05 22.9 0.0 0.31 12.0 0.1 3.5 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX48016.1 - 0.00043 20.7 1.7 0.0071 16.8 0.0 3.2 2 2 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX48016.1 - 0.0014 18.4 0.1 1.6 8.7 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX48016.1 - 0.0016 18.3 0.2 0.26 11.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat PL48 PF15903.5 EKX48016.1 - 0.0024 16.9 0.7 0.0034 16.4 0.7 1.1 1 0 0 1 1 1 1 Filopodia upregulated, FAM65 TPR_9 PF13371.6 EKX48016.1 - 0.0033 17.5 0.0 0.02 15.1 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat bMG5 PF17972.1 EKX48016.1 - 0.008 16.5 0.1 0.77 10.1 0.0 2.7 2 0 0 2 2 2 1 Bacterial Alpha-2-macroglobulin MG5 domain TPR_15 PF13429.6 EKX48016.1 - 0.011 15.0 0.2 0.024 13.9 0.1 1.5 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_20 PF14561.6 EKX48016.1 - 0.023 15.0 2.0 0.07 13.5 0.3 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EKX48016.1 - 0.045 14.4 0.1 9 7.0 0.0 2.8 1 1 0 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.17 EKX48016.1 - 0.046 14.2 0.3 0.33 11.4 0.1 2.0 1 1 0 1 1 1 0 Bacterial transcriptional activator domain Trm112p PF03966.16 EKX48017.1 - 6.8e-07 29.8 0.0 1.1e-06 29.1 0.0 1.3 1 1 0 1 1 1 1 Trm112p-like protein Glyco_transf_49 PF13896.6 EKX48019.1 - 4.8e-65 220.1 0.0 6.4e-28 98.1 0.0 3.8 2 2 2 4 4 4 3 Glycosyl-transferase for dystroglycan GvpL_GvpF PF06386.11 EKX48019.1 - 0.025 14.5 0.0 0.084 12.8 0.1 1.8 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF pPIWI_RE_REase PF18154.1 EKX48019.1 - 0.13 12.3 0.0 0.58 10.1 0.0 2.1 2 0 0 2 2 2 0 REase associating with pPIWI_RE FBPase PF00316.20 EKX48020.1 - 1.8e-34 118.9 0.0 2.5e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Collagen PF01391.18 EKX48021.1 - 3.1e-27 94.1 86.8 9.6e-10 38.1 19.2 3.3 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) Collagen PF01391.18 EKX48022.1 - 4.2e-27 93.7 84.5 1.7e-09 37.3 18.7 3.3 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) GNT-I PF03071.15 EKX48023.1 - 2.2e-30 105.8 2.6 6.4e-30 104.3 2.6 1.7 1 1 0 1 1 1 1 GNT-I family Glycos_transf_2 PF00535.26 EKX48023.1 - 0.094 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Lebercilin PF15619.6 EKX48024.1 - 0.012 15.2 11.7 0.016 14.8 11.7 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease tRNA-synt_2c PF01411.19 EKX48024.1 - 0.06 11.8 1.0 0.077 11.5 1.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (A) BshC PF10079.9 EKX48024.1 - 0.12 11.1 5.9 0.14 10.9 5.9 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC KxDL PF10241.9 EKX48024.1 - 0.18 12.1 6.3 0.29 11.4 4.2 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein UPF0242 PF06785.11 EKX48024.1 - 0.27 11.3 14.5 0.44 10.6 14.1 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 EKX48024.1 - 0.28 10.7 3.6 0.33 10.5 3.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2570 PF10828.8 EKX48024.1 - 0.32 10.9 5.2 0.2 11.5 3.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) Fib_alpha PF08702.10 EKX48024.1 - 0.91 9.7 8.1 0.47 10.6 1.4 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family REJ PF02010.15 EKX48025.1 - 2.2e-33 115.7 0.1 2.2e-33 115.7 0.1 3.6 3 1 1 4 4 4 1 REJ domain GPS PF01825.21 EKX48025.1 - 1.8e-08 34.8 1.9 1.8e-08 34.8 1.9 3.3 2 0 0 2 2 2 1 GPCR proteolysis site, GPS, motif TIG PF01833.24 EKX48025.1 - 3.8e-06 26.9 70.2 0.051 13.7 0.1 13.3 11 1 0 11 11 11 5 IPT/TIG domain DSL PF01414.19 EKX48025.1 - 5.2e-05 23.4 10.4 5.2e-05 23.4 10.4 3.8 3 0 0 3 3 3 2 Delta serrate ligand DUF916 PF06030.12 EKX48025.1 - 0.017 15.1 0.1 0.32 11.1 0.0 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF916) DUF3391 PF11871.8 EKX48025.1 - 0.074 13.6 1.2 0.18 12.4 1.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Saf_2TM PF18303.1 EKX48025.1 - 0.17 11.4 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain DUF4604 PF15377.6 EKX48025.1 - 7.8 6.9 10.4 15 6.0 10.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Ras PF00071.22 EKX48027.1 - 1.1e-62 210.4 0.2 1.4e-62 210.1 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EKX48027.1 - 7.7e-32 110.0 0.0 1.3e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EKX48027.1 - 1.4e-12 47.4 0.2 1.7e-12 47.2 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EKX48027.1 - 2.5e-08 34.0 0.1 4.2e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EKX48027.1 - 2.4e-07 30.8 0.2 0.014 15.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EKX48027.1 - 4.5e-06 26.4 0.3 9.6e-06 25.3 0.1 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EKX48027.1 - 3.3e-05 23.3 0.3 4.8e-05 22.8 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EKX48027.1 - 7.4e-05 22.3 0.2 9.5e-05 21.9 0.2 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF4238 PF14022.6 EKX48027.1 - 0.0025 17.4 0.1 0.0027 17.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) PduV-EutP PF10662.9 EKX48027.1 - 0.0047 16.7 0.0 0.15 11.8 0.0 2.3 1 1 1 2 2 2 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 EKX48027.1 - 0.0091 15.5 0.0 0.042 13.4 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 EKX48027.1 - 0.012 16.0 0.1 0.038 14.4 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 EKX48027.1 - 0.016 14.5 0.0 0.044 13.1 0.0 1.7 1 0 0 1 1 1 0 Septin AAA_29 PF13555.6 EKX48027.1 - 0.061 13.1 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EKX48027.1 - 0.061 13.0 0.1 0.095 12.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EKX48027.1 - 0.073 13.4 0.1 0.16 12.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EKX48027.1 - 0.13 12.8 2.3 0.54 10.8 2.3 2.1 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 EKX48027.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_trans_NIPA PF05653.14 EKX48028.1 - 1.3e-11 44.2 0.9 1.3e-11 44.2 0.9 1.6 2 0 0 2 2 2 1 Magnesium transporter NIPA EamA PF00892.20 EKX48028.1 - 6.2e-05 23.2 23.5 0.0002 21.5 2.9 3.7 3 2 1 4 4 4 2 EamA-like transporter family TMEM234 PF10639.9 EKX48028.1 - 0.0012 18.8 1.4 0.0018 18.3 0.3 1.8 2 0 0 2 2 2 1 Putative transmembrane family 234 PUNUT PF16913.5 EKX48028.1 - 0.026 13.7 0.6 0.026 13.7 0.6 2.1 1 1 0 2 2 2 0 Purine nucleobase transmembrane transport DUF4131 PF13567.6 EKX48028.1 - 0.21 11.3 7.8 0.76 9.4 0.1 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) Multi_Drug_Res PF00893.19 EKX48028.1 - 0.79 10.4 9.0 0.055 14.1 1.7 2.6 1 1 2 3 3 3 0 Small Multidrug Resistance protein Yip1 PF04893.17 EKX48028.1 - 9.3 5.9 25.5 0.19 11.4 11.0 2.9 2 1 1 3 3 3 0 Yip1 domain Pkinase PF00069.25 EKX48029.1 - 8.8e-52 176.1 0.0 1.1e-51 175.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX48029.1 - 5.3e-49 166.8 0.0 5.9e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX48029.1 - 7.8e-05 21.6 0.0 0.0001 21.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX48029.1 - 0.00024 21.1 0.7 0.0059 16.6 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.25 EKX48030.1 - 1.3e-50 172.3 0.0 1.5e-50 172.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX48030.1 - 9.1e-49 166.1 0.0 1e-48 165.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX48030.1 - 8.9e-05 21.4 0.0 0.00013 20.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX48030.1 - 0.00033 20.7 0.8 0.0062 16.5 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Sigma70_ner PF04546.13 EKX48031.1 - 0.1 12.5 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region MORN PF02493.20 EKX48032.1 - 5.6e-08 32.2 2.7 0.00065 19.4 0.7 3.6 3 0 0 3 3 3 2 MORN repeat CENP-F_leu_zip PF10473.9 EKX48032.1 - 0.0091 16.0 3.3 0.0091 16.0 3.3 1.7 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HAUS-augmin3 PF14932.6 EKX48032.1 - 0.051 13.2 3.9 0.097 12.2 3.9 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF4482 PF14818.6 EKX48032.1 - 0.087 13.7 7.3 0.3 11.9 3.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) SpoOE-like PF09388.10 EKX48032.1 - 0.23 11.4 1.4 6.9 6.7 2.0 2.3 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein Adaptin_binding PF10199.9 EKX48032.1 - 0.53 10.9 6.5 1.2 9.7 6.5 1.6 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 YabA PF06156.13 EKX48032.1 - 0.65 10.7 4.6 0.26 11.9 1.5 1.8 2 0 0 2 2 2 0 Initiation control protein YabA DUF724 PF05266.14 EKX48032.1 - 1.7 8.4 13.5 0.32 10.8 6.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) WD40 PF00400.32 EKX48033.1 - 3.1e-21 75.3 10.1 5.2e-06 27.1 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX48033.1 - 5.2e-18 65.1 6.0 2e-06 28.0 0.3 4.4 4 1 0 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX48033.1 - 5.8e-07 28.8 0.6 0.0036 16.3 0.5 4.0 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EKX48033.1 - 5.6e-05 23.1 0.1 0.0076 16.1 0.0 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EKX48033.1 - 0.19 10.4 3.2 1.1 7.8 0.6 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 IKI3 PF04762.12 EKX48033.1 - 0.24 9.3 0.5 1.6 6.6 0.1 2.2 2 1 0 2 2 2 0 IKI3 family Glyco_transf_41 PF13844.6 EKX48034.1 - 2.9e-113 378.8 0.1 3.4e-60 203.8 0.0 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 UQ_con PF00179.26 EKX48035.1 - 1.7e-47 160.6 0.0 2.1e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EKX48035.1 - 0.094 13.0 0.2 0.12 12.6 0.2 1.5 1 1 0 1 1 1 0 RWD domain UbiA PF01040.18 EKX48036.1 - 1.1e-09 38.0 3.6 1.1e-09 38.0 3.6 1.9 2 0 0 2 2 2 1 UbiA prenyltransferase family GST_N_2 PF13409.6 EKX48037.1 - 7.2e-16 58.3 0.0 1.9e-15 56.9 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EKX48037.1 - 9.4e-12 44.8 0.0 2.3e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EKX48037.1 - 1.4e-09 38.0 0.1 5.2e-09 36.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EKX48037.1 - 4.5e-05 23.6 0.2 0.00011 22.4 0.2 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EKX48037.1 - 0.00017 21.9 0.0 0.23 11.9 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 EKX48037.1 - 0.091 12.6 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PDZ_2 PF13180.6 EKX48038.1 - 3.1e-05 24.2 0.1 4.3e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX48038.1 - 4.3e-05 23.8 0.2 5.8e-05 23.4 0.2 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX48038.1 - 0.0043 16.9 0.4 0.0084 15.9 0.4 1.5 1 0 0 1 1 1 1 PDZ domain Cytochrome_C554 PF13435.6 EKX48039.1 - 0.043 14.7 1.1 0.065 14.2 1.1 1.2 1 0 0 1 1 1 0 Cytochrome c554 and c-prime Zn_clus PF00172.18 EKX48040.1 - 1.8e-12 47.1 36.4 1.6e-06 28.1 11.0 2.8 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Ten_N PF06484.12 EKX48041.1 - 0.59 9.9 5.0 0.63 9.9 5.0 1.1 1 0 0 1 1 1 0 Teneurin Intracellular Region DSPn PF14671.6 EKX48042.1 - 6.8e-40 136.8 0.0 2.7e-39 134.8 0.0 1.9 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EKX48042.1 - 1.3e-16 60.6 0.0 5.8e-13 48.8 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX48042.1 - 7.7e-05 22.4 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX48042.1 - 8.5e-05 22.7 0.0 0.0002 21.5 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EKX48042.1 - 0.0089 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EKX48042.1 - 0.18 11.4 0.0 0.36 10.4 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family TraE PF05309.11 EKX48043.1 - 0.022 14.2 0.2 0.048 13.0 0.2 1.5 1 0 0 1 1 1 0 TraE protein FlaC_arch PF05377.11 EKX48043.1 - 1.7 9.1 6.7 0.39 11.1 1.8 2.4 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Filament PF00038.21 EKX48044.1 - 0.0009 18.9 34.1 0.0014 18.2 34.1 1.2 1 0 0 1 1 1 1 Intermediate filament protein ZapB PF06005.12 EKX48044.1 - 0.032 14.6 0.3 0.032 14.6 0.3 4.9 1 1 3 4 4 4 0 Cell division protein ZapB GNT-I PF03071.15 EKX48044.1 - 0.063 12.0 9.4 0.0094 14.8 4.9 1.8 1 1 1 2 2 2 0 GNT-I family Jnk-SapK_ap_N PF09744.9 EKX48044.1 - 0.11 12.7 41.9 0.79 9.9 15.1 3.5 1 1 1 3 3 3 0 JNK_SAPK-associated protein-1 DUF2188 PF09954.9 EKX48044.1 - 0.21 11.8 0.2 0.21 11.8 0.2 2.7 3 0 0 3 3 2 0 Uncharacterized protein conserved in bacteria (DUF2188) PCRF PF03462.18 EKX48044.1 - 0.64 9.8 25.6 0.55 10.1 7.2 2.2 2 0 0 2 2 2 0 PCRF domain DUF111 PF01969.17 EKX48044.1 - 0.71 8.9 5.5 1 8.4 5.5 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF111 DUF2730 PF10805.8 EKX48044.1 - 1.2 9.3 18.3 2.6 8.2 1.6 3.9 2 2 1 3 3 3 0 Protein of unknown function (DUF2730) KASH_CCD PF14662.6 EKX48044.1 - 2 8.2 42.1 0.7 9.7 25.0 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Tropomyosin_1 PF12718.7 EKX48044.1 - 2.1 8.5 33.7 2.2 8.4 23.3 2.7 1 1 0 2 2 2 0 Tropomyosin like WD40_alt PF14077.6 EKX48044.1 - 2.4 8.1 5.7 4.8 7.1 0.0 3.9 5 0 0 5 5 4 0 Alternative WD40 repeat motif APG6_N PF17675.1 EKX48044.1 - 2.6 8.6 46.8 1.2 9.7 18.9 3.2 1 1 2 3 3 3 0 Apg6 coiled-coil region CbeA_antitoxin PF06154.11 EKX48044.1 - 3.8 8.2 5.2 1 10.0 0.4 2.4 3 0 0 3 3 2 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A YabA PF06156.13 EKX48044.1 - 4.1 8.1 29.8 1.7 9.4 3.0 4.0 1 1 4 5 5 5 0 Initiation control protein YabA bZIP_1 PF00170.21 EKX48044.1 - 4.1 7.6 26.0 7 6.8 6.0 4.8 2 2 1 4 4 4 0 bZIP transcription factor Synaptobrevin PF00957.21 EKX48044.1 - 4.7 7.1 9.8 0.41 10.5 2.6 2.8 2 1 0 2 2 2 0 Synaptobrevin Seryl_tRNA_N PF02403.22 EKX48044.1 - 4.7 7.5 27.0 14 6.0 0.5 4.2 2 2 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Taxilin PF09728.9 EKX48044.1 - 5.3 6.1 37.6 2.2 7.4 20.4 2.1 1 1 1 2 2 2 0 Myosin-like coiled-coil protein Golgin_A5 PF09787.9 EKX48044.1 - 5.6 6.3 41.0 5.2 6.4 23.6 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 Calici_MSP PF05752.11 EKX48044.1 - 5.9 6.7 10.0 0.77 9.6 0.7 3.0 2 1 2 4 4 4 0 Calicivirus minor structural protein HMMR_N PF15905.5 EKX48044.1 - 7.7 5.9 35.3 6.8 6.1 20.2 2.6 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Csm2_III-A PF03750.13 EKX48044.1 - 7.9 7.4 13.5 22 5.9 6.8 2.4 1 1 1 2 2 2 0 Csm2 Type III-A C2 PF00168.30 EKX48045.1 - 1.1e-26 93.2 0.0 1.6e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 C2 domain DUF4062 PF13271.6 EKX48045.1 - 7.7e-06 26.2 0.0 1.9e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) C2 PF00168.30 EKX48046.1 - 8.9e-26 90.2 0.1 9.7e-26 90.1 0.1 1.0 1 0 0 1 1 1 1 C2 domain WD40 PF00400.32 EKX48047.1 - 2.2e-46 154.8 33.2 1e-08 35.7 0.5 12.1 12 0 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX48047.1 - 6.7e-17 61.6 2.6 0.00012 22.3 0.1 7.1 3 2 4 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX48047.1 - 5.6e-08 32.1 3.0 2.6 6.9 0.0 6.0 4 2 1 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EKX48047.1 - 1.5e-06 27.1 0.2 6.4e-05 21.7 0.2 2.7 2 1 0 2 2 2 1 Cytochrome D1 heme domain Nup160 PF11715.8 EKX48047.1 - 0.016 13.8 5.9 0.4 9.3 0.1 4.6 3 3 2 6 6 6 0 Nucleoporin Nup120/160 Lactonase PF10282.9 EKX48047.1 - 0.04 13.2 0.4 2.3 7.4 0.1 3.3 3 1 0 3 3 3 0 Lactonase, 7-bladed beta-propeller Nbas_N PF15492.6 EKX48047.1 - 0.048 13.0 5.1 5.1 6.3 0.0 4.1 4 1 1 5 5 5 0 Neuroblastoma-amplified sequence, N terminal DUF4240 PF14024.6 EKX48047.1 - 0.052 13.7 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4240) Helicase_C PF00271.31 EKX48048.1 - 1.1 9.6 4.5 20 5.6 0.5 3.1 2 0 0 2 2 2 0 Helicase conserved C-terminal domain GILT PF03227.16 EKX48049.1 - 8.2e-19 67.8 7.5 1.8e-10 41.0 2.5 2.8 3 0 0 3 3 3 2 Gamma interferon inducible lysosomal thiol reductase (GILT) Thioredoxin_4 PF13462.6 EKX48049.1 - 0.014 15.5 0.6 0.043 14.0 0.1 2.0 2 0 0 2 2 2 0 Thioredoxin BRK PF07533.16 EKX48049.1 - 0.051 13.2 0.2 14 5.4 0.0 3.4 2 1 1 3 3 3 0 BRK domain TGT PF01702.18 EKX48049.1 - 1.4 8.0 5.1 0.23 10.6 0.2 2.0 2 1 1 3 3 3 0 Queuine tRNA-ribosyltransferase potato_inhibit PF00280.18 EKX48051.1 - 3.3e-06 27.7 0.1 1.4e-05 25.6 0.0 2.1 2 0 0 2 2 2 1 Potato inhibitor I family C2 PF00168.30 EKX48051.1 - 0.13 12.5 0.1 3.7 7.9 0.0 2.5 2 0 0 2 2 2 0 C2 domain EF-hand_1 PF00036.32 EKX48052.1 - 9e-10 37.4 1.8 0.00044 19.6 0.6 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX48052.1 - 1.3e-09 37.2 1.7 0.00067 19.4 0.1 2.3 1 1 1 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EKX48052.1 - 2.2e-08 34.4 1.0 2.4e-08 34.3 1.0 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX48052.1 - 1.5e-07 30.6 4.0 0.0014 18.0 0.5 2.9 3 1 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EKX48052.1 - 5.9e-06 26.0 1.1 9.9e-06 25.3 0.5 1.6 1 1 1 2 2 2 2 EF-hand domain pair Thioredoxin PF00085.20 EKX48053.1 - 1.2e-09 38.0 0.0 3.3e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin Fibin PF15819.5 EKX48053.1 - 0.0034 17.2 3.4 0.0056 16.5 3.4 1.4 1 0 0 1 1 1 1 Fin bud initiation factor homologue DNA_pol3_delta2 PF13177.6 EKX48053.1 - 0.0081 16.0 0.0 0.0081 16.0 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase III, delta subunit cNMP_binding PF00027.29 EKX48054.1 - 2e-35 120.7 0.6 1.9e-13 50.3 0.0 3.7 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Patatin PF01734.22 EKX48054.1 - 6.3e-28 98.4 0.1 1.5e-27 97.1 0.1 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase HEPN_RES_NTD1 PF18870.1 EKX48055.1 - 0.065 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 HEPN/RES N-terminal domain 1 CRF PF00473.17 EKX48055.1 - 0.38 10.9 2.1 0.99 9.5 2.1 1.7 1 0 0 1 1 1 0 Corticotropin-releasing factor family LRR_8 PF13855.6 EKX48056.1 - 1.9e-52 174.8 60.0 1.5e-10 40.7 4.8 11.2 3 3 7 11 11 11 11 Leucine rich repeat LRR_4 PF12799.7 EKX48056.1 - 4.5e-43 144.5 67.0 1.1e-05 25.6 0.8 12.7 4 2 9 16 16 16 15 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX48056.1 - 1.5e-09 37.6 34.4 0.0069 15.9 0.5 7.2 1 1 6 7 7 7 7 Leucine-rich repeat LRR_1 PF00560.33 EKX48056.1 - 0.002 18.4 55.2 14 6.7 0.1 16.7 17 3 0 17 17 17 2 Leucine Rich Repeat DUF3464 PF11947.8 EKX48056.1 - 0.026 14.3 0.0 13 5.5 0.1 4.2 3 1 1 4 4 4 0 Photosynthesis affected mutant 68 LRR_6 PF13516.6 EKX48056.1 - 0.22 11.7 0.1 0.22 11.7 0.1 16.2 21 0 0 21 21 21 0 Leucine Rich repeat LRR_8 PF13855.6 EKX48057.1 - 2.4e-13 49.6 19.0 5.2e-08 32.5 3.3 2.9 1 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EKX48057.1 - 3.8e-09 36.7 11.9 0.00021 21.6 2.9 3.8 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX48057.1 - 5.5e-05 23.2 7.9 5.6 7.9 0.1 5.8 5 1 0 5 5 5 1 Leucine Rich Repeat eIF3_subunit PF08597.10 EKX48057.1 - 0.02 14.8 0.7 0.028 14.3 0.7 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit TAN PF11640.8 EKX48057.1 - 0.064 13.4 0.9 0.087 13.0 0.9 1.3 1 1 0 1 1 1 0 Telomere-length maintenance and DNA damage repair H-kinase_dim PF02895.14 EKX48057.1 - 0.075 13.4 0.2 0.72 10.3 0.1 2.3 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain SLATT_4 PF18186.1 EKX48057.1 - 0.091 12.4 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 ThiG PF05690.14 EKX48057.1 - 0.14 11.4 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG LRR_4 PF12799.7 EKX48058.1 - 4e-18 65.2 20.2 0.00017 21.9 0.1 6.3 4 3 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX48058.1 - 1.8e-17 62.8 12.3 1.7e-06 27.7 3.7 4.9 3 2 2 5 5 5 4 Leucine rich repeat Beta_helix PF13229.6 EKX48059.1 - 0.0015 18.4 0.0 0.0049 16.7 0.0 1.7 1 1 0 1 1 1 1 Right handed beta helix region tRNA-synt_1d PF00750.19 EKX48060.1 - 2.1e-121 405.1 0.0 2.7e-121 404.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EKX48060.1 - 2.4e-28 98.7 0.0 4.8e-28 97.7 0.0 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EKX48060.1 - 1e-17 64.5 0.2 3.2e-17 62.9 0.1 1.9 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain Anoctamin PF04547.12 EKX48061.1 - 5e-64 216.8 6.5 6.7e-64 216.4 6.5 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Tub_N PF16322.5 EKX48062.1 - 0.025 15.0 14.4 1.2 9.5 7.5 2.4 2 0 0 2 2 2 0 Tubby N-terminal DAHP_synth_1 PF00793.20 EKX48063.1 - 2.4e-57 193.9 0.0 1e-56 191.9 0.0 1.7 1 1 0 1 1 1 1 DAHP synthetase I family EF-hand_5 PF13202.6 EKX48064.1 - 0.0025 17.3 0.5 0.0084 15.6 0.0 2.2 2 0 0 2 2 2 1 EF hand S6PP_C PF08472.10 EKX48064.1 - 0.02 14.8 0.0 0.077 12.9 0.0 2.0 2 0 0 2 2 2 0 Sucrose-6-phosphate phosphohydrolase C-terminal EF-hand_1 PF00036.32 EKX48064.1 - 0.024 14.2 0.8 0.06 12.9 0.1 2.1 2 0 0 2 2 2 0 EF hand SGL PF08450.12 EKX48064.1 - 0.098 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region EF-hand_6 PF13405.6 EKX48064.1 - 0.15 12.1 0.0 0.53 10.3 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain Kinase-PPPase PF03618.14 EKX48064.1 - 0.23 11.2 2.0 0.57 9.9 2.0 1.6 1 0 0 1 1 1 0 Kinase/pyrophosphorylase Syntaxin_2 PF14523.6 EKX48064.1 - 1.5 9.3 7.9 12 6.4 0.6 3.5 3 0 0 3 3 3 0 Syntaxin-like protein FA_desaturase PF00487.24 EKX48065.1 - 1.3e-25 90.8 11.4 1.6e-25 90.4 10.7 1.6 1 1 0 1 1 1 1 Fatty acid desaturase Methyltransf_16 PF10294.9 EKX48066.1 - 1.6e-27 96.4 0.1 1.8e-27 96.2 0.1 1.0 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EKX48066.1 - 7.9e-05 22.5 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EKX48066.1 - 0.026 13.9 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EKX48066.1 - 0.036 13.6 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 EKX48066.1 - 0.042 13.6 0.0 0.083 12.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Rieske_2 PF13806.6 EKX48067.1 - 0.00021 21.2 0.0 0.00025 20.9 0.0 1.1 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain RWP-RK PF02042.15 EKX48069.1 - 3.2e-13 49.4 0.1 4.9e-13 48.8 0.1 1.2 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX48070.1 - 3.4e-10 39.7 0.1 5.4e-10 39.1 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX48071.1 - 1.9e-13 50.1 0.0 3.2e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain MttA_Hcf106 PF02416.16 EKX48071.1 - 0.073 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 mttA/Hcf106 family HTH_8 PF02954.19 EKX48071.1 - 0.18 11.6 0.4 4.1 7.3 0.1 2.2 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family XG_FTase PF03254.13 EKX48072.1 - 1.8e-07 30.2 0.1 5.4e-06 25.3 0.0 2.2 2 0 0 2 2 2 2 Xyloglucan fucosyltransferase PEP_mutase PF13714.6 EKX48073.1 - 5.1e-14 52.3 0.0 8.8e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF1992 PF09350.10 EKX48073.1 - 0.72 10.1 5.8 0.27 11.4 1.0 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF1992) GST_N_2 PF13409.6 EKX48075.1 - 1.8e-20 73.0 0.0 7.1e-20 71.1 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EKX48075.1 - 1.8e-12 47.1 0.0 3.5e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EKX48075.1 - 1.7e-11 44.2 0.0 2.9e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EKX48075.1 - 3.5e-08 33.5 0.0 7.1e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EKX48075.1 - 8.1e-07 29.4 0.0 0.0018 18.7 0.0 2.7 1 1 1 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 EKX48075.1 - 0.029 14.2 0.0 0.069 12.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain TEX12 PF15219.6 EKX48075.1 - 0.045 14.1 0.1 0.087 13.2 0.1 1.5 1 0 0 1 1 1 0 Testis-expressed 12 GST_N PF02798.20 EKX48075.1 - 0.074 13.4 0.0 0.72 10.2 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain PALP PF00291.25 EKX48076.1 - 1.3e-39 136.4 0.0 1.8e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SBDS PF01172.18 EKX48077.1 - 1.3e-17 63.6 0.0 2.1e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 EKX48077.1 - 6.4e-10 39.1 0.0 1.7e-09 37.7 0.0 1.7 2 0 0 2 2 2 1 SBDS protein C-terminal domain SET PF00856.28 EKX48078.1 - 3e-07 31.0 0.0 6e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 EKX48078.1 - 0.00011 22.9 0.9 0.0013 19.4 0.0 2.4 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding B56 PF01603.20 EKX48079.1 - 6e-184 611.8 0.8 6.8e-184 611.6 0.8 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 EKX48079.1 - 0.023 14.6 0.1 5.3 6.9 0.0 3.0 2 1 1 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Adaptin_N PF01602.20 EKX48079.1 - 0.025 13.2 0.0 0.05 12.1 0.0 1.4 1 0 0 1 1 1 0 Adaptin N terminal region HECT PF00632.25 EKX48080.1 - 4.1e-88 295.8 0.0 4.6e-88 295.7 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) TMEM237 PF15383.6 EKX48081.1 - 0.15 11.1 0.0 0.17 10.9 0.0 1.0 1 0 0 1 1 1 0 Transmembrane protein 237 Ribosomal_S3_C PF00189.20 EKX48082.1 - 1.7e-18 66.9 1.3 5.8e-18 65.2 1.3 1.9 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EKX48082.1 - 7.6e-13 48.1 0.1 1.3e-12 47.4 0.1 1.4 1 0 0 1 1 1 1 KH domain DUF2073 PF09846.9 EKX48082.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2073) UN_NPL4 PF11543.8 EKX48082.1 - 0.15 12.5 0.0 0.31 11.6 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 His_Phos_1 PF00300.22 EKX48083.1 - 5e-18 65.5 0.1 3.1e-16 59.6 0.1 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Laminin_G_3 PF13385.6 EKX48084.1 - 2e-24 86.5 0.9 1e-14 55.0 0.1 3.5 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily EPTP PF03736.17 EKX48084.1 - 1.3e-13 50.7 2.6 0.018 15.0 0.0 7.9 8 0 0 8 8 8 3 EPTP domain Lactonase PF10282.9 EKX48084.1 - 3.5e-11 43.0 0.1 2.1e-09 37.1 0.0 3.4 3 1 0 3 3 3 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 EKX48084.1 - 0.006 16.2 0.0 0.15 11.6 0.0 2.5 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region TIG PF01833.24 EKX48084.1 - 0.31 11.1 14.2 0.021 14.9 0.4 5.5 7 0 0 7 7 7 0 IPT/TIG domain ATG11 PF10377.9 EKX48085.1 - 1.7e-11 44.3 0.0 1.7e-11 44.3 0.0 3.4 4 0 0 4 4 4 1 Autophagy-related protein 11 APG17 PF04108.12 EKX48085.1 - 1.5e-06 27.6 3.9 1.5e-06 27.6 3.9 4.3 2 2 1 4 4 4 2 Autophagy protein Apg17 Methyltransf_1N PF02870.15 EKX48085.1 - 0.097 13.5 0.0 0.32 11.8 0.0 1.9 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Spidroin_MaSp PF11260.8 EKX48085.1 - 0.11 12.8 0.6 11 6.4 0.2 3.6 2 1 1 3 3 3 0 Major ampullate spidroin 1 and 2 MPS2 PF17060.5 EKX48085.1 - 9.2 5.4 24.8 1.2 8.3 1.1 3.3 3 0 0 3 3 3 0 Monopolar spindle protein 2 Pentapeptide_4 PF13599.6 EKX48087.1 - 0.0057 16.8 0.0 0.41 10.9 0.0 2.1 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) CoiA PF06054.11 EKX48088.1 - 0.0026 17.0 0.0 0.0029 16.8 0.0 1.1 1 0 0 1 1 1 1 Competence protein CoiA-like family Methyltransf_16 PF10294.9 EKX48089.1 - 4e-24 85.3 0.5 1.1e-12 48.0 0.6 2.2 1 1 1 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 EKX48089.1 - 0.00057 19.8 0.0 0.00089 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EKX48089.1 - 0.011 15.3 0.9 0.23 11.0 0.1 2.8 2 1 1 3 3 3 0 Methyltransferase small domain Glyco_transf_92 PF01697.27 EKX48089.1 - 0.02 14.5 0.0 0.054 13.2 0.0 1.6 2 0 0 2 2 2 0 Glycosyltransferase family 92 Methyltransf_12 PF08242.12 EKX48089.1 - 0.027 15.2 0.1 0.082 13.7 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 EKX48089.1 - 0.034 13.8 0.0 0.057 13.0 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_25 PF13649.6 EKX48089.1 - 0.036 14.8 0.2 18 6.1 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EKX48089.1 - 0.084 12.0 0.0 0.21 10.7 0.0 1.6 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family RNaseH_like PF04308.12 EKX48089.1 - 0.22 11.4 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease H-like ResIII PF04851.15 EKX48090.1 - 9e-22 77.9 0.0 1.2e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EKX48090.1 - 1.7e-19 70.3 0.0 2.1e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EKX48090.1 - 0.00076 19.2 0.0 0.00097 18.9 0.0 1.2 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 EKX48090.1 - 0.0097 15.2 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EKX48090.1 - 0.013 15.8 0.0 0.075 13.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EKX48090.1 - 0.026 14.9 0.0 0.25 11.8 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Inositol_P PF00459.25 EKX48091.1 - 2e-31 109.5 0.0 3.1e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family Toxin_27 PF08099.11 EKX48091.1 - 6 7.1 7.4 1.1 9.4 1.1 2.7 2 0 0 2 2 2 0 Scorpion calcine family Mito_carr PF00153.27 EKX48093.1 - 7.6e-24 83.5 1.4 8.8e-12 44.8 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Fungus-induced PF10917.8 EKX48094.1 - 0.75 10.2 5.7 3.8 7.9 0.3 3.1 3 0 0 3 3 3 0 Fungus-induced protein ProRS-C_1 PF09180.11 EKX48097.1 - 1.2e-21 76.6 0.2 6.4e-21 74.3 0.0 2.2 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 EKX48097.1 - 1.9e-19 70.4 0.0 3.3e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EKX48097.1 - 1e-13 51.2 0.3 3.6e-13 49.5 0.1 2.1 2 0 0 2 2 2 1 Anticodon binding domain NHL PF01436.21 EKX48098.1 - 1.1e-38 129.3 0.7 1.1e-06 28.3 0.0 6.0 6 0 0 6 6 6 5 NHL repeat SGL PF08450.12 EKX48098.1 - 4.8e-16 59.1 4.4 4.9e-09 36.1 0.5 5.3 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region DUF839 PF05787.13 EKX48098.1 - 1.1e-06 28.1 2.1 0.17 11.0 0.1 3.5 1 1 3 4 4 4 3 Bacterial protein of unknown function (DUF839) Phytase-like PF13449.6 EKX48098.1 - 0.00026 21.0 0.0 3.8 7.4 0.0 3.8 2 2 1 4 4 4 2 Esterase-like activity of phytase Arylesterase PF01731.20 EKX48098.1 - 0.045 13.9 0.0 4.6 7.5 0.0 3.3 4 0 0 4 4 4 0 Arylesterase SARAF PF06682.12 EKX48099.1 - 0.034 13.8 0.6 0.07 12.8 0.6 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis O-ag_pol_Wzy PF14296.6 EKX48099.1 - 0.79 8.3 11.1 1.1 7.8 11.1 1.1 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy WW PF00397.26 EKX48100.1 - 4.5e-09 36.2 5.6 1.8e-08 34.3 3.3 2.6 2 0 0 2 2 2 1 WW domain PfkB PF00294.24 EKX48100.1 - 5.1e-08 32.6 0.0 7e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase ABC1 PF03109.16 EKX48101.1 - 0.11 12.7 0.1 0.2 11.8 0.1 1.3 1 0 0 1 1 1 0 ABC1 family BIR PF00653.21 EKX48102.1 - 1.4e-09 38.5 0.3 3.9e-09 37.0 0.3 1.8 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain PCI PF01399.27 EKX48103.1 - 1e-22 80.6 2.0 1e-22 80.6 2.0 2.2 3 0 0 3 3 3 1 PCI domain ANAPC3 PF12895.7 EKX48103.1 - 0.012 15.8 0.7 1.4 9.2 0.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 STI1 PF17830.1 EKX48103.1 - 0.042 13.8 2.9 6.9 6.7 0.4 3.2 3 0 0 3 3 3 0 STI1 domain TPR_7 PF13176.6 EKX48103.1 - 0.13 12.3 0.6 28 5.0 0.0 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX48103.1 - 0.13 13.1 0.1 5.2 8.2 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat RPM2 PF08579.11 EKX48103.1 - 0.62 10.5 0.1 0.62 10.5 0.1 3.5 3 1 1 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) Complex1_LYR_2 PF13233.6 EKX48103.1 - 7.5 7.4 6.3 1.1 10.0 0.2 2.7 3 1 0 3 3 3 0 Complex1_LYR-like Ank_4 PF13637.6 EKX48105.1 - 1.1e-19 70.5 0.2 1.2e-06 28.9 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX48105.1 - 5.5e-19 68.5 0.2 2e-14 53.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX48105.1 - 1.4e-11 44.4 0.3 4e-06 27.0 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX48105.1 - 7.3e-09 35.7 0.6 0.04 14.4 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EKX48105.1 - 1.1e-07 31.6 0.1 0.92 10.3 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat TPH PF13868.6 EKX48106.1 - 1.9e-48 164.8 151.4 2.4e-46 157.9 136.9 3.0 1 1 2 3 3 3 2 Trichohyalin-plectin-homology domain RWP-RK PF02042.15 EKX48107.1 - 2.4e-13 49.8 0.0 4.9e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX48107.1 - 0.093 12.5 0.3 0.55 10.1 0.3 2.1 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family Glyco_transf_4 PF13439.6 EKX48108.1 - 0.0017 18.4 1.1 0.57 10.2 0.2 2.7 1 1 1 2 2 2 2 Glycosyltransferase Family 4 TPR_1 PF00515.28 EKX48109.1 - 4.2e-15 54.8 2.1 3.9e-08 32.8 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX48109.1 - 2.6e-14 52.1 1.4 9.3e-06 25.4 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 EKX48109.1 - 3.8e-09 36.6 2.4 1.7e-05 24.9 0.5 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX48109.1 - 2.8e-08 33.9 3.7 0.033 15.0 0.2 3.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX48109.1 - 4e-08 33.4 0.6 0.00079 19.7 0.1 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX48109.1 - 8.3e-07 28.6 0.0 0.00051 19.7 0.0 2.6 2 0 0 2 2 2 2 TPR repeat SAP PF02037.27 EKX48109.1 - 2.5e-06 27.1 0.0 2.5e-06 27.1 0.0 2.9 3 0 0 3 3 3 1 SAP domain TPR_16 PF13432.6 EKX48109.1 - 3.3e-06 27.6 3.9 0.00012 22.6 0.6 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX48109.1 - 3e-05 23.7 1.7 0.56 10.2 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX48109.1 - 3.3e-05 23.6 0.4 0.18 11.9 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX48109.1 - 0.00013 21.9 0.1 0.042 14.1 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX48109.1 - 0.00036 21.0 0.5 0.0015 19.0 0.6 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 EKX48109.1 - 0.00062 20.2 0.6 0.74 10.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX48109.1 - 0.0039 17.5 0.0 0.061 13.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 EKX48109.1 - 0.12 11.5 0.0 4.2 6.5 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat WAC_Acf1_DNA_bd PF10537.9 EKX48110.1 - 0.097 13.2 0.1 0.21 12.1 0.1 1.5 1 0 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal Bax1-I PF01027.20 EKX48111.1 - 1.2e-33 116.7 29.1 2.3e-33 115.8 29.1 1.4 1 1 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 CcmD PF04995.14 EKX48111.1 - 2.5 8.3 6.5 0.42 10.7 0.7 2.7 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) Cupin_4 PF08007.12 EKX48112.1 - 2e-49 168.8 0.3 5.1e-49 167.5 0.1 1.5 1 1 1 2 2 2 1 Cupin superfamily protein Cupin_8 PF13621.6 EKX48112.1 - 1.3e-07 31.6 0.0 0.0047 16.7 0.0 2.4 1 1 1 2 2 2 2 Cupin-like domain Cupin_2 PF07883.11 EKX48112.1 - 0.011 15.4 0.1 0.04 13.6 0.0 1.9 2 0 0 2 2 2 0 Cupin domain AraC_binding PF02311.19 EKX48112.1 - 0.016 15.1 0.1 0.096 12.6 0.0 2.2 2 0 0 2 2 2 0 AraC-like ligand binding domain Abhydrolase_6 PF12697.7 EKX48113.1 - 4.4e-12 47.1 0.0 5.3e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EKX48113.1 - 1.7e-05 24.2 0.0 2.4e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 EKX48113.1 - 0.0088 15.7 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 EKX48113.1 - 0.019 14.6 0.0 0.034 13.8 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 EKX48113.1 - 0.16 10.8 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme UPF0020 PF01170.18 EKX48114.1 - 0.007 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 EKX48114.1 - 0.041 13.2 0.0 0.067 12.4 0.0 1.3 1 0 0 1 1 1 0 N-6 DNA Methylase N6_N4_Mtase PF01555.18 EKX48114.1 - 0.047 13.4 0.0 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 DNA methylase Ribosomal_60s PF00428.19 EKX48114.1 - 0.097 13.3 0.8 0.56 10.8 1.0 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein CENP-B_dimeris PF09026.10 EKX48114.1 - 0.21 12.0 5.7 0.41 11.1 5.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HTH_38 PF13936.6 EKX48115.1 - 2.4e-05 24.0 0.7 5.1e-05 22.9 0.7 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 EKX48115.1 - 0.00062 19.8 1.1 0.001 19.2 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 EKX48115.1 - 0.00068 19.4 0.1 0.0015 18.2 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain CENP-B_N PF04218.13 EKX48115.1 - 0.0016 18.1 0.2 0.0029 17.2 0.2 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain Sigma70_r4 PF04545.16 EKX48115.1 - 0.0027 17.2 0.2 0.005 16.3 0.2 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_37 PF13744.6 EKX48115.1 - 0.02 14.9 0.1 0.034 14.1 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 EKX48115.1 - 0.05 13.5 0.1 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 MarR family HTH_38 PF13936.6 EKX48116.1 - 2.4e-05 24.0 0.7 5.1e-05 22.9 0.7 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 EKX48116.1 - 0.00062 19.8 1.1 0.001 19.2 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 EKX48116.1 - 0.00068 19.4 0.1 0.0015 18.2 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain CENP-B_N PF04218.13 EKX48116.1 - 0.0016 18.1 0.2 0.0029 17.2 0.2 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain Sigma70_r4 PF04545.16 EKX48116.1 - 0.0027 17.2 0.2 0.005 16.3 0.2 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_37 PF13744.6 EKX48116.1 - 0.02 14.9 0.1 0.034 14.1 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 EKX48116.1 - 0.05 13.5 0.1 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 MarR family HTH_38 PF13936.6 EKX48117.1 - 2.1e-05 24.2 0.7 4.5e-05 23.1 0.7 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 EKX48117.1 - 0.00052 20.1 1.0 0.0009 19.3 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 EKX48117.1 - 0.00059 19.6 0.1 0.0013 18.4 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain CENP-B_N PF04218.13 EKX48117.1 - 0.0013 18.3 0.2 0.0025 17.4 0.2 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain Sigma70_r4 PF04545.16 EKX48117.1 - 0.0024 17.4 0.2 0.0044 16.5 0.2 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_37 PF13744.6 EKX48117.1 - 0.018 15.0 0.1 0.03 14.3 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 EKX48117.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_38 PF13936.6 EKX48118.1 - 2.1e-05 24.2 0.7 4.5e-05 23.1 0.7 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 EKX48118.1 - 0.00052 20.1 1.0 0.0009 19.3 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 EKX48118.1 - 0.00058 19.6 0.1 0.0013 18.4 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain CENP-B_N PF04218.13 EKX48118.1 - 0.0013 18.3 0.2 0.0025 17.4 0.2 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain Sigma70_r4 PF04545.16 EKX48118.1 - 0.0023 17.4 0.2 0.0044 16.5 0.2 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_37 PF13744.6 EKX48118.1 - 0.017 15.0 0.1 0.03 14.3 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 EKX48118.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_38 PF13936.6 EKX48119.1 - 2.4e-05 24.0 0.7 5.1e-05 22.9 0.7 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 EKX48119.1 - 0.00058 19.9 1.1 0.001 19.2 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 EKX48119.1 - 0.00066 19.4 0.1 0.0015 18.2 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain CENP-B_N PF04218.13 EKX48119.1 - 0.0015 18.1 0.2 0.0029 17.2 0.2 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain Sigma70_r4 PF04545.16 EKX48119.1 - 0.0026 17.2 0.2 0.005 16.3 0.2 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_37 PF13744.6 EKX48119.1 - 0.023 14.6 0.1 0.04 13.9 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.7 EKX48119.1 - 0.05 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 MarR family ExoD PF06055.12 EKX48120.1 - 5.3e-25 87.8 10.5 1e-24 86.9 10.5 1.5 1 0 0 1 1 1 1 Exopolysaccharide synthesis, ExoD WW PF00397.26 EKX48120.1 - 1.5e-13 50.5 2.0 2.3e-13 50.0 2.0 1.3 1 0 0 1 1 1 1 WW domain Sec8_exocyst PF04048.14 EKX48121.1 - 3.9e-07 30.0 0.6 1.6e-06 28.1 0.6 2.2 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 EKX48121.1 - 0.00044 19.6 3.4 0.00092 18.6 3.4 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Dioxygenase_N PF04444.14 EKX48121.1 - 0.029 14.2 0.1 0.1 12.5 0.1 1.9 1 0 0 1 1 1 0 Catechol dioxygenase N terminus Voldacs PF03517.13 EKX48122.1 - 0.046 13.9 1.3 0.19 11.9 0.7 2.0 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling Choline_transpo PF04515.12 EKX48123.1 - 2e-81 273.7 36.3 2e-81 273.7 36.3 3.1 2 1 1 3 3 3 2 Plasma-membrane choline transporter SLATT_1 PF18181.1 EKX48124.1 - 1.8e-21 76.3 2.0 6.1e-21 74.6 0.7 2.3 2 0 0 2 2 2 1 SMODS and SLOG-associating 2TM effector domain 1 DUF4231 PF14015.6 EKX48124.1 - 7.7e-08 32.7 1.1 3.4e-07 30.7 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4231) NHL PF01436.21 EKX48125.1 - 2.7e-37 124.9 22.2 3.1e-07 30.1 0.6 6.6 6 1 0 6 6 6 6 NHL repeat SGL PF08450.12 EKX48125.1 - 3.7e-18 66.0 9.3 0.0014 18.3 0.0 5.6 1 1 4 6 6 6 5 SMP-30/Gluconolactonase/LRE-like region DUF5128 PF17170.4 EKX48125.1 - 6e-17 61.8 2.1 1.4e-06 27.7 0.1 3.7 2 1 1 3 3 3 3 6-bladed beta-propeller DUF4934 PF16288.5 EKX48125.1 - 9.5e-08 31.9 0.0 0.1 12.5 0.0 3.7 2 1 2 4 4 4 3 Domain of unknown function (DUF4934) SBBP PF06739.11 EKX48125.1 - 9.6e-06 25.5 4.5 0.53 10.3 0.0 5.6 6 0 0 6 6 6 1 Beta-propeller repeat Ldl_recept_b PF00058.17 EKX48125.1 - 0.00052 20.4 0.0 38 4.9 0.0 4.8 4 0 0 4 4 4 0 Low-density lipoprotein receptor repeat class B DUF4774 PF15999.5 EKX48125.1 - 0.048 13.5 0.1 45 4.0 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4774) potato_inhibit PF00280.18 EKX48125.1 - 0.38 11.5 7.3 25 5.6 0.0 4.2 5 0 0 5 5 5 0 Potato inhibitor I family IGPS PF00218.21 EKX48126.1 - 5.7e-06 25.7 0.6 8.2e-06 25.2 0.6 1.2 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase zf-C3HC4_2 PF13923.6 EKX48127.1 - 4.3e-11 42.5 12.5 8.9e-11 41.5 12.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX48127.1 - 3.2e-07 30.1 12.3 7.3e-07 29.0 12.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX48127.1 - 5e-07 29.6 6.1 5e-07 29.6 6.1 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EKX48127.1 - 7.5e-07 29.2 7.5 2.5e-06 27.5 7.6 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 EKX48127.1 - 2.2e-06 27.4 6.2 4.3e-06 26.5 6.2 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 EKX48127.1 - 7.4e-06 26.2 11.5 1.7e-05 25.1 11.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EKX48127.1 - 9.7e-06 25.4 15.7 1.8e-05 24.5 15.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Cytidylate_kin2 PF13189.6 EKX48127.1 - 0.00013 22.2 0.2 0.00026 21.2 0.2 1.4 1 0 0 1 1 1 1 Cytidylate kinase-like family zf-RING_5 PF14634.6 EKX48127.1 - 0.00097 19.0 13.3 0.002 18.0 13.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain WW PF00397.26 EKX48127.1 - 0.0011 19.0 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 WW domain zf-rbx1 PF12678.7 EKX48127.1 - 0.0011 19.2 9.5 0.0023 18.2 9.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 EKX48127.1 - 0.0024 17.9 8.5 0.0044 17.1 8.5 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 U-box PF04564.15 EKX48127.1 - 0.0026 17.9 0.0 0.0058 16.8 0.0 1.6 1 0 0 1 1 1 1 U-box domain Prok-RING_4 PF14447.6 EKX48127.1 - 0.021 14.7 12.8 0.041 13.7 12.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EKX48127.1 - 0.58 10.0 8.9 1.4 8.7 8.7 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EKX48127.1 - 5.1 7.2 8.8 12 6.0 8.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Semialdhyde_dhC PF02774.18 EKX48130.1 - 5.6e-53 179.8 0.0 7.2e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EKX48130.1 - 1.8e-16 60.7 0.0 3.7e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain PWI PF01480.17 EKX48131.1 - 3.1e-08 33.8 0.1 4.6e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 PWI domain Ribosomal_L37 PF08561.10 EKX48131.1 - 0.0014 19.2 5.2 0.0025 18.3 5.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 Apt1 PF10351.9 EKX48131.1 - 0.046 12.6 6.5 0.052 12.4 6.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 EKX48131.1 - 0.47 8.7 13.6 0.6 8.3 13.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 EKX48131.1 - 8.2 5.1 9.4 11 4.6 9.4 1.3 1 0 0 1 1 1 0 Presenilin AIG1 PF04548.16 EKX48132.1 - 9.5e-12 44.7 0.7 4.4e-11 42.5 0.0 2.5 2 0 0 2 2 2 1 AIG1 family Lipase_3 PF01764.25 EKX48132.1 - 4.3e-11 42.9 0.0 9.6e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) MMR_HSR1 PF01926.23 EKX48132.1 - 2e-07 31.1 0.1 9.2e-07 28.9 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Septin PF00735.18 EKX48132.1 - 0.00013 21.4 0.0 0.00041 19.7 0.0 1.8 2 0 0 2 2 2 1 Septin AXE1 PF05448.12 EKX48132.1 - 0.0034 16.1 0.0 0.006 15.3 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) ABC_tran PF00005.27 EKX48132.1 - 0.015 15.8 0.7 0.096 13.2 0.0 2.7 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 EKX48132.1 - 0.022 14.5 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EKX48132.1 - 0.026 14.4 0.1 0.092 12.6 0.1 1.9 1 1 0 1 1 1 0 RsgA GTPase Roc PF08477.13 EKX48132.1 - 0.04 14.1 0.0 0.16 12.2 0.0 2.1 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF2974 PF11187.8 EKX48132.1 - 0.07 12.7 0.0 0.97 8.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Sigma54_activat PF00158.26 EKX48132.1 - 0.088 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF87 PF01935.17 EKX48132.1 - 0.089 12.9 0.9 0.35 10.9 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain DUF3918 PF13056.6 EKX48132.1 - 0.11 12.2 1.5 0.44 10.2 1.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3918) Dynamin_N PF00350.23 EKX48132.1 - 0.12 12.5 4.6 1.2 9.1 0.0 3.3 2 1 1 3 3 3 0 Dynamin family DUF4507 PF14964.6 EKX48133.1 - 0.0099 14.8 1.5 0.2 10.5 0.2 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4507) Lsr2 PF11774.8 EKX48134.1 - 0.046 13.9 0.6 0.046 13.9 0.6 1.8 2 0 0 2 2 2 0 Lsr2 KELK PF15796.5 EKX48134.1 - 9.5 6.8 10.7 3.4 8.2 6.1 2.3 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GATase PF00117.28 EKX48135.1 - 6.4e-36 123.9 0.0 7.2e-36 123.7 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EKX48135.1 - 8e-08 32.3 0.0 2.4e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 Chorismate_bind PF00425.18 EKX48136.1 - 6e-88 294.7 0.0 6.9e-88 294.5 0.0 1.0 1 0 0 1 1 1 1 chorismate binding enzyme Beta_helix PF13229.6 EKX48137.1 - 3.1e-07 30.4 0.0 6.3e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 EKX48137.1 - 0.0019 17.5 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) OmpA_like PF16961.5 EKX48137.1 - 0.2 11.3 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative OmpA-OmpF-like porin family Methyltransf_31 PF13847.6 EKX48138.1 - 2.2e-14 53.5 0.0 2.6e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX48138.1 - 5.2e-12 46.3 0.0 7.1e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX48138.1 - 2.3e-11 44.2 0.0 3.1e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX48138.1 - 2.5e-07 31.4 0.0 4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EKX48138.1 - 0.00031 20.4 0.0 0.00041 20.0 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_8 PF05148.15 EKX48138.1 - 0.038 13.9 0.0 0.054 13.3 0.0 1.4 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_32 PF13679.6 EKX48138.1 - 0.067 13.2 0.0 0.067 13.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EKX48138.1 - 0.079 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Peripla_BP_3 PF13377.6 EKX48138.1 - 0.14 12.4 0.0 0.19 12.1 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein-like domain Choline_transpo PF04515.12 EKX48139.1 - 7.8e-80 268.5 40.6 7.8e-80 268.5 40.6 2.8 3 0 0 3 3 3 1 Plasma-membrane choline transporter PKS_DE PF18369.1 EKX48139.1 - 0.44 11.1 0.1 0.44 11.1 0.1 1.7 2 0 0 2 2 2 0 Polyketide synthase dimerisation element domain DUF1013 PF06242.11 EKX48140.1 - 1.5 8.8 8.7 0.57 10.2 0.2 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1013) ArfGap PF01412.18 EKX48142.1 - 5.2e-40 136.2 0.0 1.2e-39 134.9 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 EKX48142.1 - 3.1e-21 76.2 3.6 5.2e-21 75.5 3.6 1.3 1 0 0 1 1 1 1 BAR domain of APPL family Ank_2 PF12796.7 EKX48142.1 - 5.6e-12 46.1 8.4 3.7e-07 30.6 1.3 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX48142.1 - 1.5e-07 31.6 5.5 2.6e-06 27.6 1.9 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX48142.1 - 4.2e-05 23.6 1.4 1.6 9.5 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat RGI1 PF10843.8 EKX48142.1 - 0.0011 18.7 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Respiratory growth induced protein 1 Ank_4 PF13637.6 EKX48142.1 - 0.0026 18.3 0.3 0.8 10.4 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX48142.1 - 0.0028 18.1 4.3 0.26 11.8 0.7 3.8 4 0 0 4 4 4 1 Ankyrin repeat Cluap1 PF10234.9 EKX48142.1 - 0.0057 16.1 0.6 0.013 14.9 0.6 1.5 1 0 0 1 1 1 1 Clusterin-associated protein-1 BAR_2 PF10455.9 EKX48142.1 - 0.031 13.4 0.8 0.051 12.7 0.8 1.3 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking bZIP_1 PF00170.21 EKX48142.1 - 0.66 10.1 2.5 19 5.5 0.4 3.0 2 1 1 3 3 3 0 bZIP transcription factor SPOB_ab PF14682.6 EKX48142.1 - 3.7 7.7 4.9 1.8 8.7 0.2 2.6 2 1 1 3 3 3 0 Sporulation initiation phospho-transferase B, C-terminal GSHPx PF00255.19 EKX48143.1 - 6.3e-23 80.4 0.0 9.7e-23 79.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione peroxidase GGACT PF06094.12 EKX48143.1 - 4.2e-10 40.3 0.2 7.9e-10 39.4 0.2 1.4 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like SPT6_acidic PF14632.6 EKX48144.1 - 0.047 14.3 8.1 1.1 9.9 0.5 3.0 2 1 1 3 3 3 0 Acidic N-terminal SPT6 BRF1 PF07741.13 EKX48144.1 - 0.056 13.8 6.4 0.22 11.9 2.5 2.2 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Fz PF01392.22 EKX48145.1 - 2.7e-05 24.7 6.2 4.5e-05 24.0 6.2 1.5 1 1 0 1 1 1 1 Fz domain MORN PF02493.20 EKX48147.1 - 1.5e-11 43.5 15.1 3.9e-06 26.4 1.4 6.1 6 0 0 6 6 6 4 MORN repeat Fringe PF02434.16 EKX48148.1 - 0.017 14.5 0.0 0.076 12.4 0.0 2.1 1 1 0 1 1 1 0 Fringe-like Cwf_Cwc_15 PF04889.12 EKX48149.1 - 0.006 16.4 3.3 0.007 16.1 3.3 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF3246 PF11596.8 EKX48149.1 - 0.04 13.4 3.1 0.057 12.8 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) SAPS PF04499.15 EKX48149.1 - 0.055 12.2 0.9 0.069 11.9 0.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF3245 PF11595.8 EKX48149.1 - 0.056 13.9 4.7 0.075 13.5 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Ribosomal_60s PF00428.19 EKX48149.1 - 0.2 12.3 11.6 0.082 13.5 2.6 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein PPP4R2 PF09184.11 EKX48149.1 - 0.2 11.2 1.9 0.24 11.0 1.9 1.1 1 0 0 1 1 1 0 PPP4R2 Peptidase_M13_N PF05649.13 EKX48150.1 - 8.3e-75 252.8 0.0 1.1e-74 252.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 DUF2947 PF11163.8 EKX48150.1 - 0.0069 16.2 0.6 2.7 7.8 0.0 3.2 2 2 2 4 4 4 2 Protein of unknown function (DUF2947) COX4 PF02936.14 EKX48150.1 - 0.077 13.0 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Fes1 PF08609.10 EKX48151.1 - 1.5e-08 35.4 2.1 1.8e-08 35.2 0.1 2.1 3 0 0 3 3 3 1 Nucleotide exchange factor Fes1 Arm PF00514.23 EKX48151.1 - 0.0061 16.6 0.1 0.036 14.1 0.0 2.2 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat TelA PF05816.11 EKX48151.1 - 0.0068 15.5 0.9 0.066 12.3 0.1 2.2 2 0 0 2 2 2 1 Toxic anion resistance protein (TelA) V-ATPase_H_C PF11698.8 EKX48151.1 - 0.012 15.7 0.0 1.1 9.4 0.0 3.1 2 2 0 2 2 2 0 V-ATPase subunit H HEAT_EZ PF13513.6 EKX48151.1 - 0.074 13.6 1.1 1.3 9.6 0.1 3.2 3 0 0 3 3 3 0 HEAT-like repeat Ribosomal_L32p PF01783.23 EKX48152.1 - 3.4e-11 43.2 4.5 6e-11 42.4 4.5 1.4 1 0 0 1 1 1 1 Ribosomal L32p protein family Aa_trans PF01490.18 EKX48154.1 - 4.9e-15 55.1 15.0 1.1e-14 54.0 12.3 2.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein VCBS PF13517.6 EKX48155.1 - 0.00011 22.8 14.5 25 5.6 0.1 6.0 1 1 4 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF4148 PF13663.6 EKX48155.1 - 0.0037 17.4 0.5 2.1 8.6 0.1 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF4148) WD40_alt PF14077.6 EKX48155.1 - 0.1 12.5 0.6 2.4e+02 1.7 0.0 4.2 4 0 0 4 4 4 0 Alternative WD40 repeat motif Anoctamin PF04547.12 EKX48156.1 - 1.1e-62 212.4 16.3 2e-46 158.8 7.5 2.1 1 1 1 2 2 2 2 Calcium-activated chloride channel DUF4932 PF16286.5 EKX48156.1 - 0.018 14.3 1.3 0.023 14.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4932) PDZ_6 PF17820.1 EKX48157.1 - 4.2e-05 23.3 0.0 9.5e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX48157.1 - 0.0003 21.0 0.1 0.0017 18.7 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX48157.1 - 0.087 13.2 0.1 0.26 11.6 0.0 1.9 2 0 0 2 2 2 0 PDZ domain TIG PF01833.24 EKX48158.1 - 8e-05 22.6 0.2 0.001 19.1 0.0 2.7 2 0 0 2 2 2 1 IPT/TIG domain DUF5122 PF17164.4 EKX48158.1 - 0.19 12.1 1.6 7.3 7.0 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller Laminin_B PF00052.18 EKX48158.1 - 0.19 11.6 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 Laminin B (Domain IV) Ank_2 PF12796.7 EKX48159.1 - 2.3e-21 76.2 1.6 8.7e-12 45.5 0.8 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX48159.1 - 1.9e-16 60.2 0.7 2.4e-09 37.6 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX48159.1 - 5.1e-16 58.3 6.5 0.00024 21.4 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EKX48159.1 - 7.5e-16 58.0 4.6 1.4e-06 28.4 0.4 3.4 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX48159.1 - 4.4e-15 54.3 0.5 8.1e-05 22.7 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat RWP-RK PF02042.15 EKX48160.1 - 5.4e-14 51.9 0.0 8.4e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain 2_5_RNA_ligase2 PF13563.6 EKX48162.1 - 4.8e-21 75.3 0.0 5.9e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily PPR_2 PF13041.6 EKX48163.1 - 2.3e-61 203.8 6.8 8.1e-15 54.7 0.1 10.2 2 2 8 10 10 10 10 PPR repeat family PPR PF01535.20 EKX48163.1 - 2e-56 184.4 28.4 4.9e-08 32.7 0.2 11.0 11 0 0 11 11 10 10 PPR repeat PPR_1 PF12854.7 EKX48163.1 - 2.4e-48 161.5 0.3 3.5e-08 33.0 0.0 9.7 9 1 1 10 10 10 8 PPR repeat PPR_3 PF13812.6 EKX48163.1 - 8.8e-47 157.0 0.0 1e-11 44.8 0.0 8.4 3 2 5 9 9 9 8 Pentatricopeptide repeat domain PPR_long PF17177.4 EKX48163.1 - 1.9e-30 105.9 1.3 2.1e-14 53.4 0.0 4.3 1 1 3 4 4 4 4 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EKX48163.1 - 9.9e-07 29.1 10.2 0.79 10.7 0.1 8.2 7 3 2 9 9 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX48163.1 - 6.8e-06 26.5 6.8 1.2 9.7 0.0 5.7 5 2 1 6 6 6 2 Tetratricopeptide repeat RPN7 PF10602.9 EKX48163.1 - 0.00051 19.8 1.6 2.4 7.8 0.1 4.1 3 2 1 4 4 4 2 26S proteasome subunit RPN7 SPOB_a PF14689.6 EKX48163.1 - 0.001 18.7 0.2 0.33 10.7 0.0 3.5 3 0 0 3 3 3 1 Sensor_kinase_SpoOB-type, alpha-helical domain ANAPC3 PF12895.7 EKX48163.1 - 0.0086 16.3 3.3 7.5 6.9 0.0 4.2 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 FtsK_gamma PF09397.10 EKX48163.1 - 0.0094 15.7 0.1 29 4.6 0.0 3.8 3 0 0 3 3 3 0 Ftsk gamma domain TPR_4 PF07721.14 EKX48163.1 - 0.01 16.4 1.0 2.1 9.2 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EKX48163.1 - 0.014 15.4 0.4 24 5.3 0.0 4.6 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX48163.1 - 0.017 15.3 1.4 19 5.8 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EKX48163.1 - 0.11 12.2 0.8 2 8.2 0.0 2.7 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.28 EKX48163.1 - 2.7 7.9 4.3 16 5.5 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat GFO_IDH_MocA PF01408.22 EKX48165.1 - 1.4e-20 74.4 0.0 2.6e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 EKX48165.1 - 0.00028 21.4 0.0 0.00063 20.3 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent P_gingi_FimA PF06321.11 EKX48165.1 - 0.2 11.8 0.1 1.1 9.3 0.0 2.1 1 1 0 2 2 2 0 Major fimbrial subunit protein (FimA) Cupin_8 PF13621.6 EKX48167.1 - 1.6e-32 113.2 1.5 3e-30 105.8 1.5 3.3 1 1 0 1 1 1 1 Cupin-like domain BSP_II PF05432.11 EKX48167.1 - 1.3 8.7 46.3 0.036 13.8 39.3 1.9 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DUF4778 PF16008.5 EKX48167.1 - 2.4 8.1 8.3 3.4 7.6 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) ALMT PF11744.8 EKX48167.1 - 3.1 6.5 5.7 4.3 6.1 5.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SID-1_RNA_chan PF13965.6 EKX48167.1 - 4.8 5.5 4.1 6.3 5.1 4.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SLC12 PF03522.15 EKX48167.1 - 6.4 5.7 11.3 8.7 5.2 11.3 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Myco_arth_vir_N PF09610.10 EKX48168.1 - 0.88 9.7 3.1 1.6 8.9 3.1 1.4 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) A2L_zn_ribbon PF08792.10 EKX48169.1 - 0.079 12.7 1.3 0.2 11.4 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain Palm_thioest PF02089.15 EKX48170.1 - 2.3e-19 70.2 0.0 3.5e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 EKX48170.1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein TPM_phosphatase PF04536.14 EKX48171.1 - 6.7e-06 26.3 0.0 9.4e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 TPM domain YtfJ_HI0045 PF09695.10 EKX48171.1 - 0.074 12.7 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (YtfJ_HI0045) ABC_membrane PF00664.23 EKX48172.1 - 1.6e-61 208.4 14.9 2.1e-61 208.0 14.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region DAP_B PF07930.12 EKX48172.1 - 0.056 13.4 0.0 0.095 12.7 0.0 1.3 1 0 0 1 1 1 0 D-aminopeptidase, domain B CobD_Cbib PF03186.13 EKX48172.1 - 2.3 7.4 11.5 6.4 5.9 0.0 3.0 1 1 1 3 3 3 0 CobD/Cbib protein cNMP_binding PF00027.29 EKX48173.1 - 2.2e-13 50.1 0.0 4.1e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EKX48173.1 - 6.4e-11 42.1 5.3 1.4e-10 40.9 4.6 2.0 1 1 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EKX48173.1 - 2.9e-10 39.8 15.0 5.6e-10 38.9 15.0 1.5 1 0 0 1 1 1 1 Ion transport protein Noelin-1 PF12308.8 EKX48173.1 - 0.13 12.2 0.2 0.33 11.0 0.2 1.6 1 0 0 1 1 1 0 Neurogenesis glycoprotein TFIIE_alpha PF02002.17 EKX48174.1 - 7.1e-16 58.0 3.5 7.1e-16 58.0 3.5 1.7 2 0 0 2 2 2 1 TFIIE alpha subunit Rrf2 PF02082.20 EKX48174.1 - 2.1e-05 24.8 0.2 5.1e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Transcriptional regulator HTH_12 PF08461.10 EKX48174.1 - 0.05 13.6 0.1 0.17 11.9 0.1 1.9 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain FancD2 PF14631.6 EKX48176.1 - 5.7e-190 633.8 26.4 1.1e-189 632.8 26.4 1.4 1 1 0 1 1 1 1 Fanconi anaemia protein FancD2 nuclease FANCI_S2 PF14676.6 EKX48176.1 - 0.0021 18.4 7.4 0.016 15.5 0.0 4.2 2 1 2 4 4 4 1 FANCI solenoid 2 Nop14 PF04147.12 EKX48177.1 - 5.7e-08 31.5 27.2 7.3e-08 31.1 27.2 1.1 1 0 0 1 1 1 1 Nop14-like family DUF4407 PF14362.6 EKX48177.1 - 0.84 8.9 10.9 0.98 8.7 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MMR_HSR1 PF01926.23 EKX48179.1 - 2.3e-12 47.0 0.0 4.2e-12 46.2 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EKX48179.1 - 0.00049 20.0 0.0 0.0012 18.8 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase MeaB PF03308.16 EKX48179.1 - 0.0012 17.9 0.1 0.0017 17.4 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 EKX48179.1 - 0.0016 18.0 0.0 0.0036 16.8 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EKX48179.1 - 0.063 13.3 0.2 0.67 10.0 0.1 2.1 2 0 0 2 2 2 0 Dynamin family Mod_r PF07200.13 EKX48181.1 - 0.0035 17.5 1.3 0.0056 16.8 1.3 1.3 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein UPF0449 PF15136.6 EKX48181.1 - 0.13 12.8 2.7 0.46 11.0 2.7 1.9 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 SEFIR PF08357.11 EKX48181.1 - 0.14 12.4 1.0 0.23 11.7 1.0 1.4 1 1 0 1 1 1 0 SEFIR domain Polyketide_cyc2 PF10604.9 EKX48185.1 - 4.1e-07 30.4 0.1 4.9e-07 30.1 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport cNMP_binding PF00027.29 EKX48186.1 - 3e-11 43.2 0.1 5.7e-08 32.7 0.0 3.5 4 0 0 4 4 4 2 Cyclic nucleotide-binding domain PTEN_C2 PF10409.9 EKX48186.1 - 1.5e-08 34.5 0.0 2.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein CID_GANP PF16766.5 EKX48186.1 - 0.19 11.9 0.5 0.56 10.4 0.4 1.8 2 0 0 2 2 2 0 Binding region of GANP to ENY2 Lipase_3 PF01764.25 EKX48187.1 - 7.6e-06 25.8 0.0 1.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EKX48187.1 - 0.0018 18.9 0.1 0.0022 18.7 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EKX48187.1 - 0.0025 17.5 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.8 EKX48187.1 - 0.0066 16.0 0.0 0.013 15.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 EKX48187.1 - 0.028 14.3 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 EKX48187.1 - 0.029 14.1 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 EKX48187.1 - 0.037 13.6 0.0 0.057 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Thioesterase PF00975.20 EKX48187.1 - 0.16 12.1 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain RNA_pol_L_2 PF13656.6 EKX48188.1 - 5e-26 90.3 0.0 7.2e-26 89.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EKX48188.1 - 4.3e-09 35.7 0.0 6e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Pkinase PF00069.25 EKX48189.1 - 3.3e-35 121.7 0.2 1.1e-34 120.0 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain LRR_8 PF13855.6 EKX48189.1 - 5.6e-27 93.3 63.7 4.5e-08 32.7 3.6 10.7 4 2 8 13 13 13 11 Leucine rich repeat Pkinase_Tyr PF07714.17 EKX48189.1 - 2.3e-22 79.5 0.0 9.4e-22 77.5 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase LRR_4 PF12799.7 EKX48189.1 - 2.7e-14 53.0 76.3 0.0016 18.8 1.1 12.4 4 2 5 12 12 12 7 Leucine Rich repeats (2 copies) Roc PF08477.13 EKX48189.1 - 5.3e-14 52.5 0.0 1.2e-13 51.3 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase COR PF16095.5 EKX48189.1 - 3.7e-13 49.7 0.0 1.2e-12 48.1 0.0 1.8 1 1 0 1 1 1 1 C-terminal of Roc, COR, domain Ras PF00071.22 EKX48189.1 - 5.4e-08 32.6 0.0 1.3e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Ras family Pkinase_fungal PF17667.1 EKX48189.1 - 0.0054 15.6 0.0 0.011 14.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase TniB PF05621.11 EKX48189.1 - 0.017 14.5 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein MMR_HSR1 PF01926.23 EKX48189.1 - 0.019 15.0 0.0 0.083 13.0 0.0 2.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase APH PF01636.23 EKX48189.1 - 0.042 13.8 0.1 2.2 8.1 0.1 2.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family SKA2 PF16740.5 EKX48189.1 - 0.064 13.1 3.5 0.29 10.9 0.2 3.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Gtr1_RagA PF04670.12 EKX48189.1 - 0.089 12.1 0.0 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region IQ PF00612.27 EKX48189.1 - 0.21 11.5 1.8 0.24 11.3 0.2 2.1 2 0 0 2 2 1 0 IQ calmodulin-binding motif LRR_9 PF14580.6 EKX48189.1 - 0.42 10.1 8.8 9.7 5.7 0.5 4.0 3 1 1 4 4 4 0 Leucine-rich repeat P66_CC PF16563.5 EKX48189.1 - 1.4 8.6 6.2 3.2 7.4 3.0 2.8 2 0 0 2 2 2 0 Coiled-coil and interaction region of P66A and P66B with MBD2 ZZ PF00569.17 EKX48189.1 - 2.1 8.2 18.4 3.2 7.7 8.2 3.3 2 0 0 2 2 2 0 Zinc finger, ZZ type His_Phos_2 PF00328.22 EKX48190.1 - 2.4e-26 93.0 0.0 2.4e-25 89.7 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Alkyl_sulf_C PF14864.6 EKX48190.1 - 0.021 15.1 0.0 7 6.9 0.0 3.0 3 0 0 3 3 3 0 Alkyl sulfatase C-terminal BSD PF03909.17 EKX48193.1 - 6.7e-11 42.0 0.1 2.1e-10 40.4 0.1 1.9 1 0 0 1 1 1 1 BSD domain baeRF_family3 PF18845.1 EKX48194.1 - 0.32 11.3 4.8 0.29 11.4 0.3 2.6 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 3 DHR10 PF18595.1 EKX48194.1 - 7.3 6.7 13.1 0.17 12.0 1.6 2.8 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain IMS PF00817.20 EKX48195.1 - 1.1e-46 158.6 0.0 1.3e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.8 EKX48195.1 - 0.0036 17.5 0.0 0.0072 16.6 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif TRCF PF03461.15 EKX48195.1 - 0.013 15.9 0.0 0.026 14.9 0.0 1.5 1 0 0 1 1 1 0 TRCF domain Atx10homo_assoc PF09759.9 EKX48196.1 - 2.5e-06 27.4 3.5 0.12 12.4 0.6 3.3 1 1 2 3 3 3 2 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 EKX48196.1 - 3.9e-06 26.7 6.2 0.2 11.7 0.0 4.6 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat WD40 PF00400.32 EKX48198.1 - 2.1e-06 28.3 9.1 0.012 16.5 0.3 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat cNMP_binding PF00027.29 EKX48200.1 - 2.9e-22 78.5 0.0 2.3e-12 46.8 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ank_4 PF13637.6 EKX48201.1 - 5.8e-22 77.8 2.5 9.3e-09 35.7 0.0 3.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX48201.1 - 9.9e-17 61.3 0.3 6.5e-13 49.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX48201.1 - 1.4e-15 57.2 1.2 4.8e-06 26.7 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX48201.1 - 2.6e-15 55.0 0.2 4.8e-05 23.4 0.0 3.6 3 1 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 EKX48201.1 - 2.7e-12 46.5 6.2 2.4e-05 24.6 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeat Pkinase_Tyr PF07714.17 EKX48202.1 - 4e-47 160.7 0.0 4.3e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX48202.1 - 1e-41 143.0 0.0 1.2e-41 142.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 EKX48202.1 - 1.3e-05 24.3 0.0 1.8e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EKX48202.1 - 5.8e-05 22.0 0.0 7.6e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX48202.1 - 0.0011 19.0 0.3 0.14 12.1 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family PIP49_C PF12260.8 EKX48202.1 - 0.029 14.0 0.0 0.035 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Kinase-like PF14531.6 EKX48202.1 - 0.088 12.1 0.0 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Hum_adeno_E3A PF05393.11 EKX48206.1 - 0.032 14.2 0.4 0.055 13.5 0.1 1.5 1 1 1 2 2 2 0 Human adenovirus early E3A glycoprotein OTU PF02338.19 EKX48207.1 - 1e-17 64.8 0.4 1.7e-17 64.1 0.4 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EKX48207.1 - 2.9e-05 23.6 6.6 0.033 13.6 0.4 2.6 2 1 1 3 3 3 2 Peptidase C65 Otubain HD_2 PF12917.7 EKX48207.1 - 0.035 13.9 0.7 0.063 13.0 0.7 1.4 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme SPT_ssu-like PF11779.8 EKX48208.1 - 1.7e-14 53.2 4.8 1.7e-14 53.2 4.8 2.1 1 1 1 2 2 2 1 Small subunit of serine palmitoyltransferase-like ACP_syn_III_C PF08541.10 EKX48209.1 - 1.6e-39 134.0 1.0 1.9e-38 130.5 0.1 2.5 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 EKX48209.1 - 7.2e-27 93.1 1.5 4.7e-25 87.3 0.3 3.3 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 EKX48209.1 - 5.4e-08 32.5 0.4 4e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 Thiolase, N-terminal domain Chal_sti_synt_C PF02797.15 EKX48209.1 - 0.00038 20.5 0.0 0.00062 19.8 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Thiolase_C PF02803.18 EKX48209.1 - 0.0084 15.8 1.8 0.091 12.4 0.8 2.9 2 1 0 2 2 2 1 Thiolase, C-terminal domain Diphthami_syn_2 PF01902.17 EKX48209.1 - 0.012 15.2 0.2 0.018 14.5 0.2 1.2 1 0 0 1 1 1 0 Diphthamide synthase Ketoacyl-synt_C PF02801.22 EKX48209.1 - 0.013 15.6 0.0 4.8 7.2 0.0 2.7 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain FAE1_CUT1_RppA PF08392.12 EKX48209.1 - 0.058 12.7 0.0 0.32 10.2 0.0 1.9 1 1 1 2 2 2 0 FAE1/Type III polyketide synthase-like protein Ribosomal_L22 PF00237.19 EKX48209.1 - 0.075 13.3 0.0 0.22 11.8 0.0 1.8 1 1 1 2 2 2 0 Ribosomal protein L22p/L17e TPP_enzyme_C PF02775.21 EKX48209.1 - 0.41 10.4 2.9 0.9 9.3 0.1 2.9 3 1 1 4 4 4 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain F-box-like PF12937.7 EKX48212.1 - 4.2e-05 23.4 2.2 0.0001 22.1 1.4 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EKX48212.1 - 0.0019 18.0 0.4 0.0019 18.0 0.4 2.9 4 0 0 4 4 4 1 F-box domain SRR1 PF07985.12 EKX48213.1 - 5.8e-12 45.5 0.1 1e-11 44.7 0.1 1.4 1 0 0 1 1 1 1 SRR1 TRAM_LAG1_CLN8 PF03798.16 EKX48216.1 - 2.5e-23 82.9 24.8 3.2e-23 82.5 24.2 1.4 2 0 0 2 2 2 1 TLC domain Sigma_reg_N PF13800.6 EKX48216.1 - 0.096 13.0 0.2 12 6.3 0.0 2.6 2 0 0 2 2 2 0 Sigma factor regulator N-terminal TrbE PF11100.8 EKX48216.1 - 0.11 12.7 2.6 0.24 11.7 1.6 2.1 1 1 0 1 1 1 0 Conjugal transfer protein TrbE NMT1 PF09084.11 EKX48217.1 - 1.1e-17 64.7 0.0 1.6e-10 41.3 0.0 2.2 2 0 0 2 2 2 2 NMT1/THI5 like SPT_ssu-like PF11779.8 EKX48218.1 - 2.5e-13 49.4 13.5 9.8e-13 47.5 13.5 1.9 1 1 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like Bac_transf PF02397.16 EKX48218.1 - 0.15 11.7 0.4 0.3 10.7 0.2 1.6 1 1 0 1 1 1 0 Bacterial sugar transferase TMEM219 PF14940.6 EKX48219.1 - 0.032 13.8 0.5 0.045 13.3 0.5 1.3 1 0 0 1 1 1 0 Transmembrane 219 TMEM219 PF14940.6 EKX48220.1 - 0.019 14.5 0.4 0.028 14.0 0.4 1.2 1 0 0 1 1 1 0 Transmembrane 219 Phage_int_SAM_4 PF13495.6 EKX48221.1 - 0.0023 18.4 0.1 0.38 11.2 0.1 2.5 2 0 0 2 2 2 2 Phage integrase, N-terminal SAM-like domain TMEM219 PF14940.6 EKX48222.1 - 0.019 14.5 0.4 0.028 14.0 0.4 1.2 1 0 0 1 1 1 0 Transmembrane 219 mTERF PF02536.14 EKX48223.1 - 1.6e-46 158.7 7.0 1.4e-15 57.0 0.0 5.2 2 2 3 5 5 5 5 mTERF DUF2949 PF11165.8 EKX48223.1 - 0.013 15.9 0.6 27 5.2 0.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2949) HTH_26 PF13443.6 EKX48223.1 - 0.053 14.0 0.1 4.6 7.8 0.0 3.4 3 0 0 3 3 3 0 Cro/C1-type HTH DNA-binding domain Methyltransf_16 PF10294.9 EKX48224.1 - 7.9e-19 68.0 1.4 5.8e-13 48.9 0.0 2.1 1 1 1 2 2 2 2 Lysine methyltransferase GidB PF02527.15 EKX48224.1 - 0.011 15.0 0.0 0.066 12.5 0.0 2.0 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G MTS PF05175.14 EKX48224.1 - 0.016 14.7 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Met_10 PF02475.16 EKX48224.1 - 0.094 12.5 0.0 0.16 11.7 0.0 1.4 1 1 0 1 1 1 0 Met-10+ like-protein RNA_pol_L PF01193.24 EKX48224.1 - 0.1 12.0 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Actin PF00022.19 EKX48226.1 - 4.6e-20 71.6 0.0 6e-15 54.8 0.0 2.1 1 1 1 2 2 2 2 Actin LRR_4 PF12799.7 EKX48227.1 - 3.5e-12 46.3 12.4 0.00061 20.1 2.5 4.4 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX48227.1 - 7.1e-12 44.9 11.7 2.8e-06 27.0 0.4 3.6 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 EKX48227.1 - 0.83 10.4 11.2 20 6.2 0.3 5.8 5 1 0 5 5 5 0 Leucine Rich Repeat Peptidase_C15 PF01470.17 EKX48230.1 - 2.5e-05 24.5 0.1 0.077 13.1 0.0 2.4 1 1 1 2 2 2 2 Pyroglutamyl peptidase TPR_16 PF13432.6 EKX48232.1 - 7.4e-34 116.1 20.2 0.00029 21.4 0.1 13.0 13 0 0 13 13 13 7 Tetratricopeptide repeat TPR_17 PF13431.6 EKX48232.1 - 2.7e-30 102.5 41.1 0.081 13.3 0.0 17.9 19 0 0 19 19 17 7 Tetratricopeptide repeat TPR_19 PF14559.6 EKX48232.1 - 6.2e-26 90.7 42.4 0.0016 18.9 2.4 13.9 11 3 5 16 16 15 8 Tetratricopeptide repeat TPR_14 PF13428.6 EKX48232.1 - 2e-22 77.9 40.1 0.13 13.1 0.1 18.1 13 3 10 23 23 17 6 Tetratricopeptide repeat TPR_2 PF07719.17 EKX48232.1 - 7.5e-22 75.6 47.2 1.3 9.3 0.0 20.6 22 0 0 22 22 19 6 Tetratricopeptide repeat TPR_1 PF00515.28 EKX48232.1 - 9.6e-21 72.7 37.2 0.2 11.5 0.0 19.3 20 0 0 20 20 20 5 Tetratricopeptide repeat TPR_12 PF13424.6 EKX48232.1 - 6.1e-20 71.3 52.8 0.0004 20.6 1.8 14.6 12 2 5 18 18 16 8 Tetratricopeptide repeat TPR_8 PF13181.6 EKX48232.1 - 2.7e-18 64.6 38.5 1.6 9.1 0.0 18.6 22 0 0 22 22 19 5 Tetratricopeptide repeat TPR_7 PF13176.6 EKX48232.1 - 1e-17 62.8 35.7 0.027 14.5 0.2 15.0 16 0 0 16 16 14 5 Tetratricopeptide repeat TPR_11 PF13414.6 EKX48232.1 - 2.8e-14 52.5 20.5 0.075 12.7 0.0 12.5 11 2 2 13 13 13 5 TPR repeat TPR_9 PF13371.6 EKX48232.1 - 1.5e-06 28.2 20.8 0.2 11.8 0.1 7.4 6 1 2 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 EKX48232.1 - 7.3e-06 26.3 22.3 0.32 11.7 0.1 9.5 13 0 0 13 13 7 3 Tetratricopeptide repeat Coatomer_E PF04733.14 EKX48232.1 - 0.0008 18.9 7.6 1.8 7.9 0.1 6.0 3 2 3 6 6 6 1 Coatomer epsilon subunit TPPII_N PF12583.8 EKX48232.1 - 0.0036 17.9 5.8 5.6 7.5 0.1 5.4 6 0 0 6 6 5 1 Tripeptidyl peptidase II N terminal TPR_20 PF14561.6 EKX48232.1 - 0.0043 17.4 13.4 0.016 15.5 0.1 6.0 5 2 0 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX48232.1 - 0.0081 16.2 7.7 3.1 8.0 0.1 6.3 7 0 0 7 7 7 1 Fis1 C-terminal tetratricopeptide repeat ComR_TPR PF18710.1 EKX48232.1 - 0.072 12.6 3.2 6.2 6.3 0.1 4.1 3 0 0 3 3 3 0 ComR tetratricopeptide DUF4919 PF16266.5 EKX48232.1 - 0.1 12.5 5.6 11 5.9 0.0 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF4919) TPR_3 PF07720.12 EKX48232.1 - 0.4 10.7 8.9 34 4.6 0.0 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX48232.1 - 0.46 10.8 40.5 0.092 13.0 2.4 8.7 8 2 1 9 9 8 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 EKX48232.1 - 0.81 9.8 14.9 25 5.0 0.1 8.0 9 0 0 9 9 7 0 MIT (microtubule interacting and transport) domain Alkyl_sulf_dimr PF14863.6 EKX48232.1 - 1.3 9.5 5.0 32 5.0 0.3 4.0 5 1 0 5 5 3 0 Alkyl sulfatase dimerisation Pre-PUA PF17832.1 EKX48234.1 - 1.9e-25 89.4 0.2 3.3e-25 88.6 0.2 1.3 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 EKX48234.1 - 4.4e-15 55.4 0.2 1e-14 54.2 0.2 1.7 1 1 0 1 1 1 1 PUA domain Pox_MCEL PF03291.16 EKX48235.1 - 1.2e-41 142.9 0.1 1.6e-41 142.5 0.1 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 EKX48235.1 - 9.2e-12 45.5 0.0 3.6e-11 43.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX48235.1 - 5.4e-10 39.8 0.1 1.7e-09 38.2 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX48235.1 - 2.2e-09 37.3 0.0 1.2e-08 34.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX48235.1 - 4.3e-09 37.0 0.0 1.1e-08 35.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX48235.1 - 2.6e-08 33.9 0.0 4.9e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 EKX48235.1 - 0.00041 20.1 0.0 0.0006 19.5 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.6 EKX48235.1 - 0.0018 18.3 0.0 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EKX48235.1 - 0.0033 16.8 0.0 0.0058 16.0 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 EKX48235.1 - 0.0045 16.6 0.1 0.0079 15.8 0.1 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW NNMT_PNMT_TEMT PF01234.17 EKX48235.1 - 0.1 11.8 0.0 0.28 10.3 0.0 1.7 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family MTS PF05175.14 EKX48235.1 - 0.12 11.9 0.0 0.38 10.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Enolase_C PF00113.22 EKX48236.1 - 1.7e-150 500.3 0.1 2.1e-150 499.9 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EKX48236.1 - 1.3e-57 193.6 0.1 1.9e-57 193.0 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EKX48236.1 - 7e-08 32.3 0.0 1.3e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like DUF4284 PF14112.6 EKX48236.1 - 0.13 13.2 0.3 0.4 11.6 0.2 1.9 1 1 1 2 2 2 0 Immunity protein 22 Methyltransf_21 PF05050.12 EKX48240.1 - 0.0051 16.8 0.0 0.0063 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Crystall PF00030.19 EKX48240.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Beta/Gamma crystallin DUF3027 PF11228.8 EKX48241.1 - 0.0098 15.9 0.3 0.014 15.4 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3027) AOC_like PF18678.1 EKX48241.1 - 0.035 13.7 0.0 0.061 12.9 0.0 1.4 1 1 0 1 1 1 0 Allene oxide cyclase barrel like domain Glyco_hydro_52 PF03512.13 EKX48241.1 - 0.12 11.4 2.1 1.3 7.9 0.8 2.0 1 1 1 2 2 2 0 Glycosyl hydrolase family 52 Ephrin_rec_like PF07699.13 EKX48242.1 - 8.4e-23 79.9 55.5 5.2e-12 45.3 5.9 12.6 8 2 5 13 13 13 7 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX48242.1 - 8.5e-05 22.9 26.7 0.00023 21.5 6.8 14.1 6 2 10 16 16 16 7 TNFR/NGFR cysteine-rich region NCD3G PF07562.14 EKX48242.1 - 0.0064 16.4 6.7 0.024 14.6 1.3 11.3 5 3 4 10 10 10 4 Nine Cysteines Domain of family 3 GPCR DSL PF01414.19 EKX48243.1 - 4.9e-14 52.3 112.6 9.7e-06 25.8 16.3 6.1 5 1 1 6 6 6 4 Delta serrate ligand EGF_2 PF07974.13 EKX48243.1 - 3.5e-11 43.3 132.6 0.0011 19.3 18.1 7.9 7 0 0 7 7 7 6 EGF-like domain Laminin_EGF PF00053.24 EKX48243.1 - 7.9e-05 22.7 105.5 0.005 17.0 10.4 6.6 1 1 5 6 6 6 2 Laminin EGF domain EB PF01683.18 EKX48243.1 - 0.063 13.6 105.3 0.38 11.1 11.4 6.4 1 1 5 6 6 6 0 EB module BRCA-2_helical PF09169.10 EKX48243.1 - 0.23 11.1 0.0 14 5.3 0.0 2.2 1 1 1 2 2 2 0 BRCA2, helical Glutaminase PF04960.15 EKX48243.1 - 0.71 9.0 4.3 10 5.2 0.3 2.2 2 0 0 2 2 2 0 Glutaminase EGF PF00008.27 EKX48243.1 - 0.84 10.0 101.2 0.064 13.6 10.1 7.0 6 2 0 6 6 6 0 EGF-like domain Arm PF00514.23 EKX48244.1 - 0.00012 21.9 4.1 0.81 9.8 0.3 3.5 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat UNC45-central PF11701.8 EKX48244.1 - 0.013 15.5 0.2 0.018 15.0 0.2 1.3 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central TMF_TATA_bd PF12325.8 EKX48245.1 - 0.0038 17.4 3.4 0.0038 17.4 3.4 2.8 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.6 EKX48245.1 - 0.019 14.4 10.0 0.085 12.2 10.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 EKX48245.1 - 0.056 13.8 10.4 0.51 10.8 0.2 4.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) LemA PF04011.12 EKX48245.1 - 0.11 12.3 4.8 1.5 8.7 1.0 2.6 1 1 1 2 2 2 0 LemA family Leu_zip PF15294.6 EKX48245.1 - 0.22 11.0 23.1 0.66 9.4 9.8 2.2 1 1 1 2 2 2 0 Leucine zipper DUF2730 PF10805.8 EKX48245.1 - 0.23 11.6 14.7 2.3 8.4 0.1 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) TMF_DNA_bd PF12329.8 EKX48245.1 - 0.32 11.0 29.2 0.75 9.8 2.8 4.2 3 1 0 4 4 4 0 TATA element modulatory factor 1 DNA binding Uds1 PF15456.6 EKX48245.1 - 0.52 10.5 18.2 2.8 8.1 12.4 3.5 1 1 2 3 3 3 0 Up-regulated During Septation Tropomyosin_1 PF12718.7 EKX48245.1 - 0.55 10.4 30.8 0.2 11.8 0.8 4.1 2 1 2 4 4 4 0 Tropomyosin like HMMR_N PF15905.5 EKX48245.1 - 0.55 9.6 24.8 0.13 11.7 21.3 1.8 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Fez1 PF06818.15 EKX48245.1 - 0.69 10.3 23.2 0.081 13.4 18.0 2.1 2 1 0 2 2 2 0 Fez1 GAS PF13851.6 EKX48245.1 - 0.78 9.1 28.4 0.29 10.5 14.6 3.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding JIP_LZII PF16471.5 EKX48245.1 - 0.95 9.7 15.3 3.5 7.9 0.7 4.0 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II CLZ PF16526.5 EKX48245.1 - 0.99 9.8 16.0 1 9.7 2.4 3.7 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Prefoldin PF02996.17 EKX48245.1 - 1 9.3 19.9 0.15 12.0 0.5 4.4 5 0 0 5 5 4 0 Prefoldin subunit UPF0242 PF06785.11 EKX48245.1 - 1 9.4 25.8 8.1 6.5 0.4 3.1 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus CENP-H PF05837.12 EKX48245.1 - 1.2 9.5 18.4 0.8 10.1 2.2 2.9 1 1 2 3 3 3 0 Centromere protein H (CENP-H) LPP PF04728.13 EKX48245.1 - 2 8.8 6.9 5.2 7.5 0.0 3.8 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Shugoshin_N PF07558.11 EKX48245.1 - 2.8 7.9 8.4 18 5.3 0.2 3.9 4 0 0 4 4 3 0 Shugoshin N-terminal coiled-coil region DUF4559 PF15112.6 EKX48245.1 - 4.2 7.0 18.3 3.4 7.3 16.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) Spc24 PF08286.11 EKX48245.1 - 5.1 7.4 20.0 1.5 9.1 0.3 3.9 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 YabA PF06156.13 EKX48245.1 - 5.6 7.7 24.4 1 10.1 0.2 4.3 3 2 1 4 4 4 0 Initiation control protein YabA FapA PF03961.13 EKX48245.1 - 6.1 5.3 16.5 0.13 10.8 4.7 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A bZIP_1 PF00170.21 EKX48245.1 - 8.7 6.5 16.8 1.4 9.0 0.6 4.1 4 0 0 4 4 4 0 bZIP transcription factor Csm1_N PF18504.1 EKX48245.1 - 9.7 6.6 22.5 0.93 9.9 0.5 4.3 1 1 4 5 5 5 0 Csm1 N-terminal domain PDZ_6 PF17820.1 EKX48246.1 - 1.5e-08 34.4 0.0 2.2e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX48246.1 - 8.3e-07 29.3 0.0 1.2e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX48246.1 - 0.012 15.9 0.0 0.017 15.4 0.0 1.2 1 0 0 1 1 1 0 PDZ domain Rhomboid_N PF12122.8 EKX48246.1 - 0.037 14.2 0.2 0.051 13.7 0.2 1.2 1 0 0 1 1 1 0 Cytoplasmic N-terminal domain of rhomboid serine protease Ion_trans PF00520.31 EKX48247.1 - 0.022 14.0 0.1 0.024 13.9 0.1 1.0 1 0 0 1 1 1 0 Ion transport protein Calici_PP_N PF08405.11 EKX48247.1 - 0.16 10.8 0.2 0.18 10.6 0.2 1.0 1 0 0 1 1 1 0 Viral polyprotein N-terminal PMSR PF01625.21 EKX48250.1 - 3.4e-58 196.2 2.1 3.9e-58 196.0 2.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase KH_1 PF00013.29 EKX48251.1 - 3.7e-07 29.9 0.0 5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 KH domain FHA PF00498.26 EKX48252.1 - 2.5e-09 37.3 0.0 4.5e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 FHA domain PARP PF00644.20 EKX48252.1 - 0.0047 16.5 2.7 1.1 8.9 0.0 2.5 3 0 0 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain Yop-YscD_cpl PF16697.5 EKX48252.1 - 0.047 14.0 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain WW PF00397.26 EKX48253.1 - 7.1e-09 35.6 0.0 1.7e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 WW domain ThiD2 PF17792.1 EKX48253.1 - 0.031 14.7 0.5 0.031 14.7 0.5 1.7 2 0 0 2 2 2 0 ThiD2 family Allexi_40kDa PF05549.11 EKX48253.1 - 0.058 12.9 2.2 0.18 11.3 0.4 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein cNMP_binding PF00027.29 EKX48255.1 - 3.1e-09 36.8 0.0 6e-08 32.6 0.0 2.4 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain EF-hand_1 PF00036.32 EKX48255.1 - 2.2e-06 26.8 0.5 5.9e-06 25.5 0.5 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EKX48255.1 - 1.9e-05 24.2 1.4 4.6e-05 23.0 0.6 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 EKX48255.1 - 0.00066 19.1 0.1 0.0018 17.7 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EKX48255.1 - 0.0011 19.3 5.4 0.0086 16.5 1.7 3.9 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 EKX48255.1 - 0.038 13.8 0.4 0.19 11.6 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair IQ PF00612.27 EKX48255.1 - 0.078 12.8 0.2 0.078 12.8 0.2 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif DUF5600 PF18150.1 EKX48256.1 - 5.4e-21 75.2 0.3 1.4e-20 73.9 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) Dynamin_N PF00350.23 EKX48256.1 - 7e-16 58.7 0.0 6.9e-14 52.3 0.0 2.3 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EKX48256.1 - 2.2e-11 43.9 0.0 5.1e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EHD_N PF16880.5 EKX48256.1 - 7.6e-06 25.7 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Roc PF08477.13 EKX48256.1 - 0.00018 21.7 0.0 0.24 11.6 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 EKX48256.1 - 0.0037 16.8 0.0 1.2 8.6 0.0 2.8 3 0 0 3 3 3 1 Ferrous iron transport protein B AAA_16 PF13191.6 EKX48256.1 - 0.0055 17.1 0.1 0.029 14.8 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AIG1 PF04548.16 EKX48256.1 - 0.011 15.0 0.0 0.15 11.3 0.0 2.2 2 0 0 2 2 2 0 AIG1 family Ras PF00071.22 EKX48256.1 - 0.012 15.2 0.0 5 6.7 0.0 2.3 2 0 0 2 2 2 0 Ras family RsgA_GTPase PF03193.16 EKX48256.1 - 0.03 14.2 0.1 5 7.0 0.0 3.2 3 0 0 3 3 3 0 RsgA GTPase Gtr1_RagA PF04670.12 EKX48256.1 - 0.071 12.5 0.1 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region DNA_pol_E_B PF04042.16 EKX48257.1 - 1.9e-37 128.7 0.1 2.6e-37 128.2 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 EKX48257.1 - 3.7e-33 114.4 0.0 6.5e-33 113.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain PDZ PF00595.24 EKX48258.1 - 2e-05 24.9 0.0 3.8e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX48258.1 - 0.038 14.3 0.0 0.062 13.6 0.0 1.3 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 EKX48258.1 - 0.068 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 PDZ domain Abi_C PF14355.6 EKX48259.1 - 0.17 12.0 2.8 0.24 11.5 0.2 2.4 2 0 0 2 2 2 0 Abortive infection C-terminus WD40 PF00400.32 EKX48261.1 - 4.6e-22 77.9 6.0 1.2e-05 25.9 0.2 6.4 5 1 1 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX48261.1 - 1.8e-15 57.0 0.1 4.6e-05 23.6 0.0 4.7 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX48261.1 - 1.1e-05 24.6 0.5 0.96 8.3 0.0 4.4 2 2 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EKX48261.1 - 5.5e-05 22.6 0.3 0.21 10.9 0.1 2.5 1 1 1 2 2 2 2 WD40-like domain PQQ_2 PF13360.6 EKX48261.1 - 0.0025 17.4 0.0 0.036 13.7 0.0 2.3 1 1 0 2 2 2 1 PQQ-like domain Nup160 PF11715.8 EKX48261.1 - 0.014 14.1 0.3 3.8 6.0 0.0 2.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Antimicrobial22 PF16047.5 EKX48261.1 - 0.023 14.6 0.4 0.059 13.2 0.4 1.7 1 0 0 1 1 1 0 Frog antimicrobial peptide Cytochrom_D1 PF02239.16 EKX48261.1 - 0.073 11.6 0.0 2.6 6.5 0.0 2.3 1 1 1 2 2 2 0 Cytochrome D1 heme domain Melibiase PF02065.18 EKX48261.1 - 0.074 12.0 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Melibiase Peptidase_C92 PF05708.12 EKX48262.1 - 9.8e-11 42.0 0.1 1.1e-06 28.8 0.0 2.3 2 0 0 2 2 2 2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family C2 PF00168.30 EKX48262.1 - 5e-05 23.5 0.0 9.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain RCDG1 PF15725.5 EKX48262.1 - 0.0058 17.0 0.2 0.015 15.7 0.2 1.7 1 0 0 1 1 1 1 Renal cancer differentiation gene 1 protein Toxin_11 PF07473.11 EKX48262.1 - 3 8.0 4.8 9.2 6.5 1.3 3.0 3 0 0 3 3 3 0 Spasmodic peptide gm9a; conotoxin from Conus species RCC1_2 PF13540.6 EKX48264.1 - 5.1e-39 131.3 69.1 2.2e-10 40.1 2.9 9.1 9 0 0 9 9 9 8 Regulator of chromosome condensation (RCC1) repeat DUF4215 PF13948.6 EKX48264.1 - 4.2e-05 23.9 10.3 4.2e-05 23.9 10.3 4.2 3 1 0 3 3 3 1 Domain of unknown function (DUF4215) RCC1 PF00415.18 EKX48264.1 - 0.0028 18.3 1.5 0.0028 18.3 1.5 10.4 11 1 0 11 11 11 3 Regulator of chromosome condensation (RCC1) repeat ZZ PF00569.17 EKX48264.1 - 0.21 11.4 8.5 3.6 7.5 0.8 3.9 2 1 1 3 3 3 0 Zinc finger, ZZ type LRR_6 PF13516.6 EKX48265.1 - 2.2e-40 133.3 45.4 0.00013 21.8 1.0 12.7 13 0 0 13 13 13 11 Leucine Rich repeat LRR_4 PF12799.7 EKX48265.1 - 1.6e-13 50.6 21.2 0.0017 18.7 0.2 7.1 3 2 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX48265.1 - 4.7e-05 23.4 27.1 11 7.0 0.1 11.0 11 2 0 11 11 11 2 Leucine Rich Repeat LRR_8 PF13855.6 EKX48265.1 - 0.0037 17.0 31.5 0.23 11.2 2.0 8.7 6 3 2 8 8 8 5 Leucine rich repeat DUF3506 PF12014.8 EKX48266.1 - 2.7e-10 40.4 0.0 3.5e-08 33.6 0.0 2.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) F-box PF00646.33 EKX48266.1 - 2.5e-05 24.0 0.3 5.6e-05 22.9 0.3 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EKX48266.1 - 8.4e-05 22.4 0.0 0.00019 21.3 0.0 1.5 1 0 0 1 1 1 1 F-box-like PALP PF00291.25 EKX48267.1 - 1.4e-14 54.2 0.0 1.8e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LYTB PF02401.18 EKX48267.1 - 0.094 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 LytB protein DASH_Dam1 PF08653.10 EKX48268.1 - 0.011 15.6 0.5 0.81 9.5 0.0 3.0 3 0 0 3 3 3 0 DASH complex subunit Dam1 Tup_N PF08581.10 EKX48268.1 - 0.13 12.6 7.4 0.42 11.0 0.4 3.1 1 1 1 2 2 2 0 Tup N-terminal zf-C4H2 PF10146.9 EKX48268.1 - 1.1 9.6 9.1 2 8.6 9.1 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein CENP-F_leu_zip PF10473.9 EKX48268.1 - 2.1 8.4 20.9 0.2 11.7 3.2 3.0 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.12 EKX48268.1 - 2.5 8.6 8.7 4.7e+02 1.3 6.5 3.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TMF_TATA_bd PF12325.8 EKX48268.1 - 2.9 8.1 16.9 1.6 9.0 13.3 2.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 EKX48268.1 - 5.6 7.0 10.5 0.31 11.1 1.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FAM183 PF14886.6 EKX48269.1 - 7.7e-17 62.0 2.2 9.8e-17 61.7 2.2 1.1 1 0 0 1 1 1 1 FAM183A and FAM183B related LLC1 PF14945.6 EKX48269.1 - 0.019 15.5 1.0 0.037 14.6 1.0 1.5 1 1 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein MPC PF03650.13 EKX48270.1 - 1.8e-32 111.7 0.5 2e-32 111.6 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers TRAM_LAG1_CLN8 PF03798.16 EKX48272.1 - 4.3e-14 52.7 2.2 8.3e-14 51.8 2.2 1.6 1 1 0 1 1 1 1 TLC domain PNTB_4TM PF12769.7 EKX48272.1 - 0.18 12.3 2.5 5.9 7.4 0.2 3.4 3 1 0 3 3 3 0 4TM region of pyridine nucleotide transhydrogenase, mitoch DsbD PF02683.15 EKX48273.1 - 6.3e-37 127.5 10.9 7.9e-37 127.2 10.9 1.1 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.6 EKX48273.1 - 8.1e-13 48.8 10.1 1e-12 48.4 10.1 1.1 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region HCV_NS4b PF01001.19 EKX48273.1 - 0.014 15.0 7.6 0.041 13.5 0.6 2.2 1 1 1 2 2 2 0 Hepatitis C virus non-structural protein NS4b NUC130_3NT PF08158.12 EKX48274.1 - 0.016 15.5 0.0 0.05 13.9 0.0 1.8 2 0 0 2 2 2 0 NUC130/3NT domain Pacs-1 PF10254.9 EKX48276.1 - 0.14 11.1 1.2 0.2 10.6 1.2 1.2 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Rad60-SLD PF11976.8 EKX48277.1 - 2.6e-06 27.1 0.0 4.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EKX48277.1 - 6.5e-06 25.8 0.0 1.4e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 EKX48277.1 - 0.016 15.3 0.0 0.042 14.0 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF601 PF04642.12 EKX48277.1 - 0.035 13.6 0.4 0.22 11.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF601 DUF2407 PF10302.9 EKX48277.1 - 0.16 12.6 0.0 0.33 11.6 0.0 1.5 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain Abhydrolase_2 PF02230.16 EKX48278.1 - 3.2e-37 128.4 0.0 3.6e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EKX48278.1 - 3e-08 33.2 0.0 0.0025 17.1 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 EKX48278.1 - 8.9e-07 28.8 0.0 1.7e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 EKX48278.1 - 2.8e-06 27.2 0.7 0.0006 19.5 0.5 2.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EKX48278.1 - 6e-05 23.0 0.0 0.00018 21.4 0.0 1.7 1 1 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 EKX48278.1 - 0.00018 21.1 0.0 0.00023 20.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EKX48278.1 - 0.00091 19.9 2.3 0.039 14.6 2.3 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Cutinase PF01083.22 EKX48278.1 - 0.0096 15.9 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 Cutinase Esterase PF00756.20 EKX48278.1 - 0.013 15.2 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 EKX48278.1 - 0.023 14.2 0.0 0.41 10.1 0.0 2.2 1 1 1 2 2 2 0 Prolyl oligopeptidase family Thioesterase PF00975.20 EKX48278.1 - 0.03 14.4 0.1 1.4 9.0 0.0 2.1 1 1 1 2 2 2 0 Thioesterase domain AXE1 PF05448.12 EKX48278.1 - 0.054 12.2 0.0 0.13 10.9 0.0 1.5 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.25 EKX48278.1 - 0.055 13.3 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.8 EKX48278.1 - 0.1 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) ABC1 PF03109.16 EKX48279.1 - 3.5e-31 107.8 0.0 6.8e-31 106.9 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EKX48279.1 - 0.035 14.0 0.1 0.17 11.8 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Vfa1 PF08432.10 EKX48280.1 - 0.027 14.8 7.1 0.038 14.3 7.1 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Dynactin_p62 PF05502.13 EKX48280.1 - 0.034 12.9 4.7 0.083 11.7 5.1 1.4 2 0 0 2 2 2 0 Dynactin p62 family Tox-ODYAM1 PF15642.6 EKX48280.1 - 0.057 12.4 9.0 0.088 11.8 9.0 1.2 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus YlqD PF11068.8 EKX48280.1 - 0.16 12.3 18.0 0.37 11.2 18.0 1.6 1 0 0 1 1 1 0 YlqD protein Borrelia_P83 PF05262.11 EKX48280.1 - 0.23 9.9 9.7 0.29 9.6 9.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein LMBR1 PF04791.16 EKX48280.1 - 0.3 9.9 0.9 0.4 9.5 0.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CTI PF06934.11 EKX48280.1 - 0.53 8.7 6.9 0.67 8.4 6.9 1.1 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) DUF188 PF02639.14 EKX48280.1 - 0.96 9.1 0.0 0.96 9.1 0.0 2.3 2 1 0 2 2 2 0 Uncharacterized BCR, YaiI/YqxD family COG1671 OmpH PF03938.14 EKX48280.1 - 1.1 9.5 20.7 1.9 8.8 20.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Connexin PF00029.19 EKX48280.1 - 1.6 8.4 4.4 2.4 7.9 4.4 1.2 1 0 0 1 1 1 0 Connexin RWP-RK PF02042.15 EKX48281.1 - 3.1e-14 52.7 0.2 5.7e-14 51.8 0.2 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_17 PF12728.7 EKX48281.1 - 0.0028 17.8 0.0 0.0045 17.1 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 EKX48281.1 - 0.0034 17.0 0.0 0.0066 16.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_8 PF02954.19 EKX48281.1 - 0.0059 16.4 0.0 0.024 14.4 0.0 2.0 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family HTH_31 PF13560.6 EKX48281.1 - 0.007 16.7 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain TnsD PF15978.5 EKX48281.1 - 0.01 14.8 0.2 0.012 14.6 0.2 1.1 1 0 0 1 1 1 0 Tn7-like transposition protein D HTH_23 PF13384.6 EKX48281.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain HTH_3 PF01381.22 EKX48281.1 - 0.057 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix HTH_28 PF13518.6 EKX48281.1 - 0.085 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_50 PF18024.1 EKX48281.1 - 0.094 12.3 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Mga PF08280.11 EKX48281.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain Solute_trans_a PF03619.16 EKX48282.1 - 2.3e-68 230.6 24.5 1.8e-40 139.2 13.0 2.3 1 1 1 2 2 2 2 Organic solute transporter Ostalpha PrmA PF06325.13 EKX48284.1 - 2.8e-08 33.5 0.3 4.1e-08 33.0 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EKX48284.1 - 5e-08 33.5 0.1 1.4e-07 32.1 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX48284.1 - 2.1e-05 25.1 0.1 4.7e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EKX48284.1 - 4.8e-05 23.0 0.2 0.00011 21.8 0.2 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EKX48284.1 - 0.0013 18.8 0.1 0.0021 18.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX48284.1 - 0.0013 18.6 0.0 0.002 18.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX48284.1 - 0.0015 19.3 0.0 0.0046 17.7 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX48284.1 - 0.002 17.9 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EKX48284.1 - 0.0055 16.6 0.0 0.0089 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 EKX48284.1 - 0.013 15.9 0.0 0.024 15.0 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase PCMT PF01135.19 EKX48284.1 - 0.063 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 EKX48284.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase HCV_NS2 PF01538.18 EKX48287.1 - 0.27 10.9 1.9 0.31 10.7 0.9 1.5 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS2 Peroxin-13_N PF04088.13 EKX48288.1 - 0.034 14.4 0.1 0.064 13.5 0.1 1.4 1 0 0 1 1 1 0 Peroxin 13, N-terminal region DUF3318 PF11780.8 EKX48288.1 - 0.092 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) Aldedh PF00171.22 EKX48289.1 - 8.3e-180 598.2 0.0 9.4e-180 598.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EKX48289.1 - 0.026 14.0 0.1 0.086 12.3 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) Fur_reg_FbpB PF13040.6 EKX48289.1 - 0.2 11.2 0.5 0.49 10.0 0.5 1.5 1 0 0 1 1 1 0 Fur-regulated basic protein B Ank_4 PF13637.6 EKX48290.1 - 1.2e-12 48.1 0.1 2.9e-09 37.3 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX48290.1 - 2.7e-12 47.1 0.2 1.6e-07 31.8 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX48290.1 - 5.5e-10 38.6 0.1 0.0012 19.2 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EKX48290.1 - 9.6e-09 35.3 0.1 0.0052 17.2 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EKX48290.1 - 9.1e-07 29.1 0.4 1e-05 25.7 0.3 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ion_trans PF00520.31 EKX48290.1 - 0.0016 17.8 8.7 0.0016 17.8 8.7 2.4 2 1 1 3 3 3 1 Ion transport protein C1_2 PF03107.16 EKX48291.1 - 0.0024 18.2 0.7 0.0024 18.2 0.7 1.9 1 1 1 2 2 2 1 C1 domain DUF1272 PF06906.11 EKX48291.1 - 0.0074 16.4 1.6 0.43 10.7 0.9 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1272) Dynactin_p62 PF05502.13 EKX48291.1 - 0.0079 15.0 1.1 0.0094 14.8 1.1 1.1 1 0 0 1 1 1 1 Dynactin p62 family zf-CHY PF05495.12 EKX48291.1 - 0.019 15.5 2.7 0.027 15.0 2.7 1.2 1 0 0 1 1 1 0 CHY zinc finger zinc_ribbon_15 PF17032.5 EKX48291.1 - 0.22 12.3 7.2 0.45 11.3 7.2 1.5 1 1 0 1 1 1 0 zinc-ribbon family DZR PF12773.7 EKX48291.1 - 0.29 11.2 8.0 1.4 9.0 8.0 2.0 1 1 0 1 1 1 0 Double zinc ribbon zf-RanBP PF00641.18 EKX48291.1 - 0.49 9.7 0.2 0.49 9.7 0.2 3.1 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others DUF3105 PF11303.8 EKX48292.1 - 0.11 12.7 2.0 0.21 11.7 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3105) DUF745 PF05335.13 EKX48292.1 - 4.7 6.9 22.3 0.094 12.4 11.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF745) NEMP PF10225.9 EKX48293.1 - 1.3e-17 64.4 14.3 1.9e-17 63.8 14.3 1.2 1 0 0 1 1 1 1 NEMP family O-antigen_lig PF13425.6 EKX48293.1 - 0.0021 16.9 2.6 0.0021 16.9 2.6 2.1 1 1 1 2 2 2 1 O-antigen ligase like membrane protein SAPIS-gp6 PF16722.5 EKX48295.1 - 0.67 10.4 7.7 2.5 8.6 0.4 3.0 2 0 0 2 2 2 0 Pathogenicity island protein gp6 in Staphylococcus HSP70 PF00012.20 EKX48295.1 - 5.3 5.1 16.3 0.071 11.3 3.0 2.7 1 1 1 2 2 2 0 Hsp70 protein DUF2259 PF10016.9 EKX48295.1 - 6 6.8 10.7 4.2 7.3 1.5 2.4 1 1 1 2 2 2 0 Predicted secreted protein (DUF2259) Erv26 PF04148.13 EKX48296.1 - 2.2e-49 168.1 10.4 5.9e-49 166.7 10.4 1.6 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 BatA PF07584.11 EKX48296.1 - 0.24 11.8 0.3 0.24 11.8 0.3 2.5 2 1 0 2 2 2 0 Aerotolerance regulator N-terminal DUF1129 PF06570.11 EKX48296.1 - 0.69 9.4 2.5 0.72 9.3 1.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) YqzM PF14141.6 EKX48296.1 - 1.7 8.8 5.6 2.9 8.0 0.6 2.5 2 0 0 2 2 2 0 YqzM-like protein DPM3 PF08285.11 EKX48296.1 - 3.8 7.8 8.9 0.7 10.1 1.9 2.3 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DnaJ PF00226.31 EKX48297.1 - 2.4e-13 50.0 0.0 4.9e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain bZIP_1 PF00170.21 EKX48298.1 - 1.7e-12 47.2 15.1 3.1e-12 46.4 15.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 EKX48298.1 - 9.7e-10 38.8 9.6 9.7e-10 38.8 9.6 1.5 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.15 EKX48298.1 - 1.2e-08 34.9 13.3 3.3e-08 33.5 9.8 2.3 1 1 1 2 2 2 2 Basic region leucine zipper HALZ PF02183.18 EKX48298.1 - 0.045 14.0 4.0 0.045 14.0 4.0 2.5 2 1 0 2 2 2 0 Homeobox associated leucine zipper HAUS6_N PF14661.6 EKX48298.1 - 0.059 12.9 3.4 0.095 12.3 3.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus YabA PF06156.13 EKX48298.1 - 0.099 13.3 1.4 0.15 12.7 0.9 1.5 1 1 0 1 1 1 0 Initiation control protein YabA Jnk-SapK_ap_N PF09744.9 EKX48298.1 - 0.2 11.9 7.6 0.32 11.2 7.6 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 UPF0242 PF06785.11 EKX48298.1 - 0.33 11.0 5.8 0.46 10.6 5.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 EKX48298.1 - 0.46 11.0 9.4 0.96 10.0 9.4 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 EKX48298.1 - 0.92 9.3 9.3 0.23 11.3 5.0 2.0 1 1 1 2 2 2 0 Septum formation initiator DUF2205 PF10224.9 EKX48298.1 - 1.3 9.0 6.4 2.8 8.0 6.4 1.5 1 0 0 1 1 1 0 Short coiled-coil protein DUF2630 PF10944.8 EKX48298.1 - 2 8.9 7.4 22 5.6 2.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) Pkinase PF00069.25 EKX48300.1 - 6.1e-61 206.1 0.0 7.2e-61 205.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX48300.1 - 1e-36 126.5 0.0 1.2e-36 126.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX48300.1 - 2e-07 30.2 0.0 2.5e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EKX48300.1 - 9.3e-05 21.5 0.5 0.00012 21.1 0.5 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EKX48300.1 - 0.0039 16.6 0.0 0.0053 16.1 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EKX48300.1 - 0.0041 16.8 0.0 0.0067 16.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EKX48300.1 - 0.0047 16.3 0.0 0.0068 15.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DEAD PF00270.29 EKX48301.1 - 9.9e-20 71.0 0.1 8.6e-18 64.7 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX48301.1 - 1.8e-07 31.5 0.0 2.4e-06 27.9 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX48301.1 - 3.4e-07 30.4 0.0 6.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EKX48301.1 - 0.0029 17.9 0.0 0.074 13.3 0.0 2.6 1 1 1 2 2 2 1 AAA domain PhoH PF02562.16 EKX48301.1 - 0.047 13.1 0.2 0.67 9.4 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein ATPase_2 PF01637.18 EKX48301.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF4586 PF15239.6 EKX48302.1 - 0.032 14.4 0.0 0.062 13.5 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4586) 2CSK_N PF08521.10 EKX48302.1 - 0.085 12.9 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal PDZ_2 PF13180.6 EKX48303.1 - 1.3e-11 44.7 0.6 2.1e-11 44.0 0.6 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX48303.1 - 1.1e-08 34.7 0.2 1.9e-08 34.0 0.2 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX48303.1 - 0.00022 21.5 0.1 0.00036 20.8 0.1 1.3 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX48303.1 - 0.0027 17.6 0.1 0.0051 16.8 0.1 1.5 1 0 0 1 1 1 1 Tricorn protease PDZ domain Sin_N PF04801.13 EKX48303.1 - 0.03 13.5 1.1 0.04 13.1 1.1 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region PDZ_4 PF17816.1 EKX48303.1 - 0.085 13.3 0.1 0.24 11.8 0.1 1.9 1 1 0 1 1 1 0 PDZ domain DUF3089 PF11288.8 EKX48304.1 - 0.58 9.7 3.7 1.4 8.4 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) UPF0220 PF05255.11 EKX48305.1 - 7.6e-16 58.1 1.7 2.4e-15 56.4 1.7 1.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0220) UPF0182 PF03699.13 EKX48305.1 - 0.019 13.1 0.3 0.022 12.9 0.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DMT_YdcZ PF04657.13 EKX48305.1 - 0.25 11.6 0.2 0.25 11.6 0.2 2.2 1 1 1 2 2 2 0 Putative inner membrane exporter, YdcZ MORN PF02493.20 EKX48306.1 - 9.9e-23 78.6 35.6 4.8e-07 29.3 0.6 6.4 7 0 0 7 7 7 4 MORN repeat Peptidase_S24 PF00717.23 EKX48306.1 - 0.1 12.6 0.0 0.96 9.4 0.0 2.5 2 1 1 3 3 3 0 Peptidase S24-like DUF4051 PF13260.6 EKX48307.1 - 0.019 14.7 2.3 2.3 8.0 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) ISG65-75 PF11727.8 EKX48307.1 - 3.3 6.8 16.6 0.061 12.5 6.7 2.2 1 1 1 2 2 2 0 Invariant surface glycoprotein POP1 PF06978.11 EKX48307.1 - 5.3 7.0 14.1 11 6.0 13.4 2.0 1 1 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 CENP-F_leu_zip PF10473.9 EKX48307.1 - 7.7 6.5 37.7 0.37 10.8 26.1 2.9 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PAPS_reduct PF01507.19 EKX48307.1 - 8.4 6.4 12.2 1.6 8.7 1.1 3.1 2 1 1 3 3 3 0 Phosphoadenosine phosphosulfate reductase family DUF3552 PF12072.8 EKX48308.1 - 0.13 11.7 64.4 0.38 10.1 21.2 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF3552) DUF5481 PF17578.2 EKX48308.1 - 0.59 10.6 3.8 0.86 10.0 2.1 2.1 1 1 0 1 1 1 0 Family of unknown function (DUF5481) DUF720 PF05302.11 EKX48308.1 - 3.3 7.6 16.4 4.8 7.0 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF720) MoaE PF02391.17 EKX48309.1 - 2.1e-23 82.7 0.1 2.5e-23 82.5 0.1 1.1 1 0 0 1 1 1 1 MoaE protein HLH PF00010.26 EKX48310.1 - 3.9e-12 45.9 0.7 7.6e-12 45.0 0.2 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_9 PF13426.7 EKX48310.1 - 4.6e-06 26.8 0.0 9.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 EKX48310.1 - 5.6e-05 23.4 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EKX48310.1 - 0.0013 18.7 0.0 0.009 16.0 0.0 2.3 1 1 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EKX48310.1 - 0.016 15.2 0.0 0.042 13.9 0.0 1.7 1 0 0 1 1 1 0 PAS domain PAS_4 PF08448.10 EKX48310.1 - 0.02 15.1 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 PAS fold Radial_spoke PF04712.12 EKX48311.1 - 0.093 11.7 10.5 0.18 10.7 10.5 1.4 1 0 0 1 1 1 0 Radial spokehead-like protein BUD22 PF09073.10 EKX48311.1 - 0.21 10.9 13.7 0.39 10.0 13.7 1.4 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 EKX48311.1 - 0.21 9.6 11.8 0.45 8.6 11.8 1.5 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 EKX48311.1 - 0.23 9.9 4.7 0.39 9.2 4.7 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cwf_Cwc_15 PF04889.12 EKX48311.1 - 0.29 10.8 10.6 0.53 10.0 10.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 EKX48311.1 - 0.61 9.6 10.6 1.3 8.6 10.6 1.5 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 EKX48311.1 - 0.8 7.8 12.2 1.4 7.0 12.2 1.4 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 EKX48311.1 - 0.86 9.4 6.1 3.1 7.6 6.1 1.9 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.14 EKX48311.1 - 2 6.6 12.3 0.097 10.9 6.0 1.8 2 0 0 2 2 2 0 CDC45-like protein Tub_N PF16322.5 EKX48311.1 - 6.7 7.1 14.8 0.43 11.0 9.3 1.7 2 0 0 2 2 2 0 Tubby N-terminal DUF4187 PF13821.6 EKX48312.1 - 0.026 14.3 0.2 0.076 12.8 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) DUF4722 PF15849.5 EKX48312.1 - 0.19 11.4 2.3 0.23 11.2 1.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4722) Glyco_transf_41 PF13844.6 EKX48313.1 - 6.2e-50 170.0 0.0 3.3e-25 88.5 0.0 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_12 PF13424.6 EKX48313.1 - 0.0017 18.6 0.1 0.93 9.8 0.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX48313.1 - 0.003 18.2 0.1 2.8 8.7 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX48313.1 - 0.0078 16.2 0.0 0.97 9.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX48313.1 - 0.012 15.4 0.0 16 5.5 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX48313.1 - 0.025 15.1 0.0 2.4 8.7 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat PALP PF00291.25 EKX48314.1 - 5.8e-87 291.8 0.4 7.4e-87 291.5 0.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EKX48314.1 - 1.3e-37 127.5 0.0 1.6e-19 69.5 0.0 2.8 2 1 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Hydrolase PF00702.26 EKX48314.1 - 0.0069 16.7 2.3 0.19 12.0 0.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase zf-RING_2 PF13639.6 EKX48315.1 - 8.5e-13 48.4 5.9 1.5e-12 47.6 5.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX48315.1 - 6.2e-09 35.6 6.8 1.1e-08 34.7 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX48315.1 - 2.4e-08 34.1 5.3 2.4e-08 34.1 5.3 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EKX48315.1 - 2.5e-06 27.4 1.0 2.5e-06 27.4 1.0 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EKX48315.1 - 6.4e-06 25.9 6.1 1.2e-05 25.0 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EKX48315.1 - 3.3e-05 23.6 6.5 5.5e-05 22.9 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EKX48315.1 - 7.6e-05 22.4 3.1 7.6e-05 22.4 3.1 2.3 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 EKX48315.1 - 0.012 15.4 12.0 0.025 14.4 12.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EKX48315.1 - 0.061 13.3 7.7 0.11 12.4 7.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain RINGv PF12906.7 EKX48315.1 - 0.1 12.7 6.2 0.22 11.6 6.2 1.5 1 0 0 1 1 1 0 RING-variant domain zf-ANAPC11 PF12861.7 EKX48315.1 - 0.11 12.5 7.6 0.27 11.3 7.4 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_16 PF17034.5 EKX48315.1 - 0.21 11.8 3.9 0.49 10.6 3.9 1.6 1 0 0 1 1 1 0 Zinc-ribbon like family FANCL_C PF11793.8 EKX48315.1 - 0.64 10.2 6.5 2 8.6 6.5 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 EKX48315.1 - 1.9 8.2 9.2 3.7 7.3 9.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type TMC PF07810.13 EKX48316.1 - 0.00017 22.2 1.1 0.00017 22.2 1.1 3.3 3 0 0 3 3 3 1 TMC domain YPEB PF14620.6 EKX48316.1 - 0.022 14.1 4.2 0.04 13.2 4.2 1.4 1 0 0 1 1 1 0 YpeB sporulation SKA1 PF07160.12 EKX48316.1 - 0.15 11.9 6.8 0.37 10.6 6.8 1.6 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 GAS PF13851.6 EKX48316.1 - 0.17 11.2 16.3 0.35 10.2 16.3 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding NPV_P10 PF05531.12 EKX48316.1 - 0.2 12.2 3.4 0.53 10.8 3.4 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 EKX48316.1 - 0.47 11.1 12.8 0.99 10.1 7.0 2.7 2 0 0 2 2 2 0 SlyX Yip1 PF04893.17 EKX48316.1 - 1.6 8.4 27.7 0.15 11.8 5.3 4.4 3 1 0 4 4 4 0 Yip1 domain SNAPc19 PF15497.6 EKX48316.1 - 6.3 7.3 11.3 2.1 8.9 6.9 2.4 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 UPF0183 PF03676.14 EKX48317.1 - 0.016 14.6 0.0 0.022 14.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0183) DUF2048 PF09752.9 EKX48319.1 - 2.5e-49 168.3 0.1 2.2e-38 132.3 0.0 2.9 1 1 1 2 2 2 2 Abhydrolase domain containing 18 Abhydrolase_6 PF12697.7 EKX48319.1 - 0.0051 17.4 0.2 0.012 16.2 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EKX48319.1 - 0.04 13.6 0.1 1 9.0 0.1 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.18 EKX48319.1 - 0.093 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family RCC1 PF00415.18 EKX48320.1 - 1e-81 269.4 27.2 4.7e-13 49.5 1.6 8.0 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX48320.1 - 2.2e-38 129.3 44.9 1.8e-08 33.9 2.0 7.3 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 EKX48320.1 - 0.096 13.1 0.8 12 6.3 0.0 3.4 4 0 0 4 4 4 0 SUKH-3 immunity protein Hira PF07569.11 EKX48320.1 - 0.12 12.1 0.3 21 4.7 0.0 3.4 4 0 0 4 4 4 0 TUP1-like enhancer of split DUF1921 PF09081.10 EKX48320.1 - 0.24 11.7 2.5 27 5.1 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1921) NHL PF01436.21 EKX48320.1 - 0.63 10.2 4.4 2.7 8.2 0.2 4.0 5 0 0 5 5 5 0 NHL repeat PKcGMP_CC PF16808.5 EKX48321.1 - 2.6e-07 30.4 57.6 0.015 15.1 2.0 7.7 3 1 4 7 7 7 6 Coiled-coil N-terminus of cGMP-dependent protein kinase HOOK PF05622.12 EKX48321.1 - 4.7e-05 21.8 28.5 4.7e-05 21.8 28.5 3.2 2 1 1 3 3 3 2 HOOK protein DUF812 PF05667.11 EKX48321.1 - 0.00049 19.1 20.1 0.00049 19.1 20.1 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF812) PDZ_6 PF17820.1 EKX48321.1 - 0.0029 17.4 0.1 0.71 9.8 0.0 3.6 3 0 0 3 3 3 1 PDZ domain HMMR_N PF15905.5 EKX48321.1 - 0.0031 17.0 24.3 0.0031 17.0 24.3 4.2 2 2 1 3 3 3 2 Hyaluronan mediated motility receptor N-terminal Fez1 PF06818.15 EKX48321.1 - 0.38 11.2 75.1 0.49 10.8 19.0 5.2 2 2 2 4 4 4 0 Fez1 LMBR1 PF04791.16 EKX48321.1 - 3.5 6.4 16.0 0.018 14.0 1.7 2.2 2 0 0 2 2 2 0 LMBR1-like membrane protein MRG PF05712.13 EKX48322.1 - 1e-22 80.4 0.2 5.5e-22 78.1 0.2 2.2 1 1 1 2 2 2 1 MRG Tudor-knot PF11717.8 EKX48322.1 - 3.5e-10 39.6 0.4 8.4e-10 38.4 0.4 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain SRP-alpha_N PF04086.13 EKX48322.1 - 4.1 7.2 29.1 5.3 6.9 21.7 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal POR_N PF01855.19 EKX48323.1 - 1.1e-70 238.0 1.3 1.9e-70 237.2 1.3 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg FAD_binding_1 PF00667.20 EKX48323.1 - 1.3e-49 168.8 0.0 2.2e-49 168.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EKX48323.1 - 6.9e-30 104.1 0.0 1.4e-29 103.1 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR PF01558.18 EKX48323.1 - 2.3e-29 102.7 0.0 4.2e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase EKR PF10371.9 EKX48323.1 - 1e-17 63.7 0.1 3e-17 62.1 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function NAD_binding_1 PF00175.21 EKX48323.1 - 1.4e-12 48.3 0.0 4.5e-12 46.6 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 EKX48323.1 - 3.3e-12 46.6 0.2 1.2e-11 44.8 0.1 2.2 2 0 0 2 2 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Fer4_6 PF12837.7 EKX48323.1 - 5.1e-09 35.8 13.3 0.00015 21.6 3.5 2.8 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_21 PF14697.6 EKX48323.1 - 7e-09 35.7 2.8 0.00079 19.5 0.2 2.6 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4 PF00037.27 EKX48323.1 - 8.5e-09 34.9 18.6 2.7e-05 23.8 1.7 3.2 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_7 PF12838.7 EKX48323.1 - 3.1e-08 34.1 7.6 1.5e-07 31.9 7.0 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 EKX48323.1 - 2.3e-07 30.9 2.7 2.3e-07 30.9 2.7 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EKX48323.1 - 2.5e-07 30.7 8.1 2.2e-06 27.7 7.5 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 EKX48323.1 - 3.9e-06 27.7 7.6 3e-05 24.9 6.6 2.7 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.6 EKX48323.1 - 2.3e-05 24.8 2.4 7.5e-05 23.1 2.4 2.0 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 EKX48323.1 - 0.0045 17.0 20.4 0.02 15.0 2.7 3.2 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EKX48323.1 - 0.0047 17.4 9.4 0.014 15.9 7.8 2.6 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_18 PF13746.6 EKX48323.1 - 0.0088 16.2 4.2 0.016 15.4 2.6 2.2 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_15 PF13459.6 EKX48323.1 - 0.013 16.2 3.6 1.6 9.5 0.2 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain Fer4_13 PF13370.6 EKX48323.1 - 0.027 15.0 8.9 2 9.0 0.4 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I IDEAL PF08858.10 EKX48323.1 - 0.09 12.5 0.8 0.24 11.2 0.8 1.7 1 0 0 1 1 1 0 IDEAL domain Fer4_3 PF12798.7 EKX48323.1 - 0.092 13.7 16.6 0.11 13.5 4.1 2.9 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_4 PF12800.7 EKX48323.1 - 0.26 11.9 16.0 0.056 14.0 1.2 3.1 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 EKX48323.1 - 2.8 8.8 5.9 24 5.8 0.4 3.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain WD40 PF00400.32 EKX48324.1 - 2e-15 56.9 4.7 0.061 14.2 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat PWWP PF00855.17 EKX48326.1 - 3.1e-14 53.1 0.0 8.6e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 PWWP domain BAH PF01426.18 EKX48326.1 - 3.7e-09 36.5 0.1 7e-09 35.6 0.1 1.5 1 0 0 1 1 1 1 BAH domain WD40 PF00400.32 EKX48326.1 - 0.0039 18.0 0.3 0.017 16.0 0.1 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat Glyco_transf_41 PF13844.6 EKX48327.1 - 4.5e-79 266.1 0.2 2.4e-49 168.0 0.0 3.0 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_2 PF07719.17 EKX48327.1 - 2.6e-35 117.7 4.4 3.8e-05 23.5 0.0 10.0 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_1 PF00515.28 EKX48327.1 - 4.4e-35 118.1 3.8 1.8e-06 27.5 0.0 8.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 EKX48327.1 - 2.1e-28 96.1 7.1 0.00074 19.5 0.0 9.0 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 EKX48327.1 - 2.2e-26 91.2 10.5 7.1e-06 25.6 0.0 8.3 4 3 4 8 8 8 6 TPR repeat TPR_17 PF13431.6 EKX48327.1 - 2.1e-24 84.1 12.8 2e-05 24.6 0.2 8.9 8 1 1 9 9 8 6 Tetratricopeptide repeat TPR_14 PF13428.6 EKX48327.1 - 1.2e-22 78.7 5.3 0.0003 21.4 0.0 9.6 5 3 6 11 11 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 EKX48327.1 - 1.8e-20 73.0 7.0 0.0024 18.1 0.0 6.8 5 2 0 6 6 5 5 Tetratricopeptide repeat TPR_16 PF13432.6 EKX48327.1 - 4.3e-20 72.1 0.0 0.00058 20.4 0.0 5.4 3 1 3 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 EKX48327.1 - 9.7e-17 61.2 3.9 0.034 14.6 0.0 5.8 4 1 0 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 EKX48327.1 - 2.5e-15 55.8 19.5 0.014 15.2 0.0 8.3 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 EKX48327.1 - 4.3e-12 45.2 8.1 0.0017 18.2 0.0 7.2 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 EKX48327.1 - 8.5e-09 35.5 7.6 1.9 9.3 0.0 8.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX48327.1 - 1e-07 32.0 0.4 0.016 15.3 0.0 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 EKX48327.1 - 1.8e-07 31.1 0.6 4 8.3 0.1 6.7 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 EKX48327.1 - 1.7e-05 24.2 6.1 0.016 14.4 0.0 3.7 1 1 1 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX48327.1 - 0.00013 22.1 2.7 0.14 12.4 0.0 4.1 2 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EKX48327.1 - 0.00046 19.7 1.3 0.031 13.7 0.6 3.5 3 1 1 4 4 4 1 MalT-like TPR region BTAD PF03704.17 EKX48327.1 - 0.0014 19.1 2.1 1.9 8.9 0.1 4.0 3 1 1 4 4 3 1 Bacterial transcriptional activator domain TPR_21 PF09976.9 EKX48327.1 - 0.0063 16.2 2.1 0.15 11.8 0.1 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat-like domain FAT PF02259.23 EKX48327.1 - 0.0078 15.5 0.3 0.38 9.9 0.1 2.5 1 1 1 2 2 2 1 FAT domain NARP1 PF12569.8 EKX48327.1 - 0.014 14.3 0.8 5.6 5.8 0.0 3.1 2 1 2 4 4 4 0 NMDA receptor-regulated protein 1 DUF2420 PF10336.9 EKX48327.1 - 0.036 14.1 0.0 0.8 9.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2420) Coatomer_E PF04733.14 EKX48327.1 - 0.11 11.8 0.1 0.72 9.2 0.0 2.3 3 0 0 3 3 3 0 Coatomer epsilon subunit HMA PF00403.26 EKX48328.1 - 2.4e-10 40.7 0.6 6e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 Heavy-metal-associated domain MerT PF02411.15 EKX48328.1 - 0.031 14.3 8.1 0.047 13.7 1.3 2.7 2 1 0 2 2 2 0 MerT mercuric transport protein DSPc PF00782.20 EKX48329.1 - 1.1e-10 41.4 0.0 1.2e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX48329.1 - 0.001 18.7 0.0 0.0012 18.4 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Ion_trans_2 PF07885.16 EKX48330.1 - 1.8e-11 43.8 7.5 4.9e-11 42.4 7.5 1.7 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EKX48330.1 - 0.11 11.7 13.2 1.1 8.4 13.2 2.4 1 1 0 1 1 1 0 Ion transport protein CRISPR_Cas2 PF09827.9 EKX48330.1 - 0.2 11.9 3.0 11 6.3 0.1 3.5 3 0 0 3 3 3 0 CRISPR associated protein Cas2 WD40 PF00400.32 EKX48332.1 - 4.5e-27 93.8 28.4 0.00061 20.5 0.0 11.2 12 0 0 12 12 12 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX48332.1 - 7.3e-23 80.7 0.5 0.0043 17.3 0.0 8.2 3 2 5 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EKX48332.1 - 3.2e-09 36.9 3.3 0.00056 19.8 0.2 4.8 2 1 1 5 5 5 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EKX48332.1 - 1.6e-05 23.8 0.9 0.035 12.8 0.0 3.3 3 1 1 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 EKX48332.1 - 0.0039 16.5 0.1 0.91 8.8 0.0 2.8 2 1 0 3 3 3 2 WD40-like domain EccE PF11203.8 EKX48333.1 - 0.021 15.2 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE 2-Hacid_dh_C PF02826.19 EKX48333.1 - 0.15 11.4 0.1 0.5 9.7 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UBA PF00627.31 EKX48334.1 - 5.4e-08 32.6 0.3 8.7e-08 31.9 0.3 1.3 1 0 0 1 1 1 1 UBA/TS-N domain Rhomboid PF01694.22 EKX48334.1 - 1.1e-07 32.0 14.3 1.6e-07 31.4 14.3 1.2 1 0 0 1 1 1 1 Rhomboid family DER1 PF04511.15 EKX48334.1 - 5.8e-07 29.6 12.0 2e-06 27.9 12.0 1.9 1 1 0 1 1 1 1 Der1-like family DUF1751 PF08551.10 EKX48334.1 - 9.6e-06 26.1 5.3 9.6e-06 26.1 5.3 2.0 2 1 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) UBA_4 PF14555.6 EKX48334.1 - 0.0016 18.2 0.1 0.0033 17.2 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain DUF2530 PF10745.9 EKX48334.1 - 2.6 8.4 5.6 14 6.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) TPR_12 PF13424.6 EKX48335.1 - 4.1e-09 36.6 14.2 0.029 14.6 0.3 5.7 4 1 0 5 5 4 4 Tetratricopeptide repeat EF-hand_1 PF00036.32 EKX48335.1 - 1.2e-08 33.9 2.1 0.00071 19.0 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EKX48335.1 - 7.8e-08 31.7 0.7 0.0054 16.6 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain TPR_2 PF07719.17 EKX48335.1 - 1.2e-07 31.3 6.4 1.8 8.9 0.1 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat EF-hand_7 PF13499.6 EKX48335.1 - 8.1e-07 29.4 0.5 4e-06 27.2 0.4 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX48335.1 - 1.4e-06 27.5 3.7 0.0083 15.6 0.4 3.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX48335.1 - 0.00013 21.8 0.5 0.41 10.5 0.0 3.2 3 0 0 3 3 3 2 EF-hand domain pair NACHT PF05729.12 EKX48335.1 - 0.00024 21.1 0.0 0.0007 19.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EKX48335.1 - 0.00029 21.1 0.0 0.0015 18.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain SNAP PF14938.6 EKX48335.1 - 0.024 14.1 2.3 0.12 11.8 0.0 2.5 2 1 1 3 3 3 0 Soluble NSF attachment protein, SNAP AAA_23 PF13476.6 EKX48335.1 - 0.036 14.6 0.0 13 6.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain TPR_1 PF00515.28 EKX48335.1 - 0.12 12.3 9.5 23 5.0 0.2 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat PDZ_6 PF17820.1 EKX48335.1 - 0.21 11.5 0.8 7.1 6.6 0.0 3.4 4 0 0 4 4 3 0 PDZ domain TPR_8 PF13181.6 EKX48335.1 - 0.21 11.9 9.0 13 6.3 0.5 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX48335.1 - 0.25 11.3 3.4 87 3.2 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX48335.1 - 1.1 9.6 7.0 0.66 10.2 0.9 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 EF-hand_1 PF00036.32 EKX48336.1 - 1.1e-12 46.6 3.9 6.8e-06 25.3 1.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX48336.1 - 5.3e-12 46.0 1.1 5.3e-12 46.0 1.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 EKX48336.1 - 2.8e-11 43.1 9.5 2.4e-09 36.9 1.5 2.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX48336.1 - 5.1e-11 41.6 1.8 1.1e-05 24.9 0.1 2.9 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EKX48336.1 - 3.6e-10 38.9 2.2 0.00041 19.7 0.2 2.6 2 0 0 2 2 2 2 EF hand Toprim_2 PF13155.6 EKX48336.1 - 0.023 15.1 0.2 0.062 13.7 0.2 1.8 1 1 0 1 1 1 0 Toprim-like SPARC_Ca_bdg PF10591.9 EKX48336.1 - 0.044 14.1 0.6 0.099 13.0 0.6 1.7 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Toprim_4 PF13662.6 EKX48336.1 - 0.071 13.6 0.1 13 6.4 0.0 2.6 1 1 1 2 2 2 0 Toprim domain Pkinase PF00069.25 EKX48338.1 - 4.9e-21 75.3 1.4 8.2e-21 74.5 1.4 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX48338.1 - 7.6e-08 31.9 0.1 1.2e-07 31.3 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX48338.1 - 0.023 14.6 0.0 0.061 13.2 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 EKX48338.1 - 0.045 13.3 0.3 0.086 12.4 0.3 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 EKX48338.1 - 0.066 12.6 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_2 PF07719.17 EKX48339.1 - 8.2e-18 63.0 10.8 0.00038 20.4 0.0 7.8 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 EKX48339.1 - 6.3e-13 48.4 12.5 0.0003 21.4 0.0 7.7 3 3 5 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX48339.1 - 1.1e-12 48.2 16.1 0.035 14.6 0.0 7.4 4 3 2 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 EKX48339.1 - 7.5e-12 44.5 10.7 0.028 14.2 0.0 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX48339.1 - 1.1e-11 45.2 11.7 0.016 15.9 0.8 5.2 5 1 0 6 6 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 EKX48339.1 - 2.6e-11 42.8 5.1 0.028 14.6 0.0 7.4 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EKX48339.1 - 1.3e-07 31.5 0.1 16 6.1 0.0 6.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX48339.1 - 1.7e-06 28.2 14.6 0.011 16.0 0.0 6.3 4 2 2 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX48339.1 - 2.6e-06 27.6 12.8 0.03 14.5 1.7 4.7 5 1 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EKX48339.1 - 0.00013 21.8 9.3 3.5 7.9 0.1 6.3 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_15 PF13429.6 EKX48339.1 - 0.00025 20.4 3.8 0.23 10.6 0.0 3.6 3 2 0 3 3 3 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EKX48339.1 - 0.00087 18.9 2.0 0.041 13.5 0.1 2.7 3 0 0 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) Coatomer_E PF04733.14 EKX48339.1 - 0.0053 16.2 0.1 2.3 7.6 0.0 3.3 2 1 1 3 3 3 1 Coatomer epsilon subunit TPR_4 PF07721.14 EKX48339.1 - 0.018 15.6 13.0 23 6.0 3.1 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EKX48339.1 - 0.035 13.8 0.0 2.5 7.8 0.0 3.1 3 0 0 3 3 3 0 TPR repeat TPR_9 PF13371.6 EKX48339.1 - 0.07 13.3 4.1 0.63 10.2 0.2 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX48339.1 - 5.7 7.0 11.6 12 6.0 0.0 6.3 8 0 0 8 8 8 0 Tetratricopeptide repeat LBR_tudor PF09465.10 EKX48340.1 - 0.00019 21.2 0.2 0.00034 20.4 0.2 1.4 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain CxC7 PF18866.1 EKX48340.1 - 0.18 12.0 2.1 2.9 8.1 0.0 3.0 3 1 0 3 3 3 0 CxC7 like cysteine cluster associated with KDZ transposases Cornichon PF03311.14 EKX48341.1 - 3.7e-08 33.7 0.3 6.1e-08 33.0 0.3 1.3 1 1 0 1 1 1 1 Cornichon protein HSF_DNA-bind PF00447.17 EKX48342.1 - 1.5e-27 96.0 1.9 1.7e-27 95.8 0.1 2.0 2 1 0 2 2 2 1 HSF-type DNA-binding HBM PF16591.5 EKX48342.1 - 0.03 13.7 2.6 0.06 12.8 2.6 1.5 1 1 0 1 1 1 0 Helical bimodular sensor domain DUF1636 PF07845.11 EKX48343.1 - 0.028 14.9 1.4 10 6.6 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1636) RNase_E_G PF10150.9 EKX48343.1 - 0.062 12.7 0.1 0.062 12.7 0.1 2.2 3 0 0 3 3 3 0 Ribonuclease E/G family UPF0184 PF03670.13 EKX48343.1 - 0.17 12.3 0.3 0.17 12.3 0.3 3.8 4 1 1 5 5 5 0 Uncharacterised protein family (UPF0184) Med30 PF11315.8 EKX48343.1 - 0.18 12.0 0.1 0.18 12.0 0.1 3.5 4 0 0 4 4 4 0 Mediator complex subunit 30 YojJ PF10372.9 EKX48343.1 - 0.7 10.0 4.5 0.74 10.0 0.2 3.1 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus Baculo_p24 PF05073.12 EKX48343.1 - 1.1 9.0 5.5 0.16 11.7 0.2 2.2 3 0 0 3 3 3 0 Baculovirus P24 capsid protein DUF948 PF06103.11 EKX48343.1 - 1.3 9.4 9.0 0.55 10.5 1.3 3.8 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 EKX48343.1 - 1.7 9.1 5.4 13 6.2 0.5 3.7 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF4250 PF14056.6 EKX48343.1 - 4.6 7.3 15.3 1.7 8.7 0.6 4.8 5 0 0 5 5 5 0 Domain of unknown function (DUF4250) Carboxyl_trans PF01039.22 EKX48344.1 - 5.8e-169 562.9 0.0 7.7e-169 562.4 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain ACC_central PF08326.12 EKX48344.1 - 1.4e-79 268.2 0.0 8.5e-77 259.0 0.0 3.2 1 1 1 2 2 2 1 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.17 EKX48344.1 - 1.7e-54 184.5 0.0 4.1e-54 183.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EKX48344.1 - 4.2e-32 111.0 0.0 1e-31 109.8 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EKX48344.1 - 1e-21 77.0 0.0 3.7e-21 75.3 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EKX48344.1 - 4.3e-09 36.1 0.0 1.4e-08 34.4 0.0 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 EKX48344.1 - 2.8e-06 27.5 0.0 6.2e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 EKX48344.1 - 8.8e-06 25.4 0.0 2.1e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EKX48344.1 - 0.00048 19.7 0.0 0.0012 18.4 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 EKX48344.1 - 0.089 12.6 0.1 9.8 6.1 0.0 2.7 2 0 0 2 2 2 0 Biotin-lipoyl like NPL PF17800.1 EKX48345.1 - 1.4e-14 54.5 0.0 1.4e-14 54.5 0.0 2.3 2 1 0 2 2 1 1 Nucleoplasmin-like domain OST-HTH PF12872.7 EKX48345.1 - 1.6e-09 37.4 0.0 2.4e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 OST-HTH/LOTUS domain YL1 PF05764.13 EKX48345.1 - 1.1e-05 25.7 22.6 1.5e-05 25.2 22.6 1.3 1 0 0 1 1 1 1 YL1 nuclear protein Nop14 PF04147.12 EKX48345.1 - 0.00027 19.4 28.5 0.00032 19.1 28.5 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 EKX48345.1 - 0.005 16.3 29.2 0.0066 15.9 29.2 1.1 1 0 0 1 1 1 1 SDA1 Nucleoplasmin PF03066.15 EKX48345.1 - 0.011 16.3 0.2 0.025 15.1 0.2 1.6 1 0 0 1 1 1 0 Nucleoplasmin/nucleophosmin domain CDC45 PF02724.14 EKX48345.1 - 0.012 13.9 19.6 0.016 13.6 19.6 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 EKX48345.1 - 0.013 14.9 25.8 0.019 14.3 25.8 1.3 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 EKX48345.1 - 0.15 11.4 29.0 0.23 10.7 29.0 1.2 1 0 0 1 1 1 0 NOA36 protein LTV PF04180.14 EKX48345.1 - 0.28 10.9 25.1 0.36 10.5 25.1 1.1 1 0 0 1 1 1 0 Low temperature viability protein LAP1C PF05609.12 EKX48345.1 - 0.31 10.1 10.1 0.35 9.9 10.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Presenilin PF01080.17 EKX48345.1 - 0.31 9.8 9.2 0.35 9.6 9.2 1.2 1 0 0 1 1 1 0 Presenilin Lin-8 PF03353.15 EKX48345.1 - 0.49 9.9 19.1 0.69 9.4 19.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4589 PF15252.6 EKX48345.1 - 0.98 9.4 14.3 1.7 8.6 14.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4589) CCSAP PF15748.5 EKX48345.1 - 1.8 8.7 15.1 2.4 8.3 15.1 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated RR_TM4-6 PF06459.12 EKX48345.1 - 2 8.2 20.8 2.6 7.8 20.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Merozoite_SPAM PF07133.11 EKX48345.1 - 2.1 8.3 37.4 3.6 7.6 37.4 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Mpp10 PF04006.12 EKX48345.1 - 2.2 6.6 30.2 2.9 6.2 30.2 1.2 1 0 0 1 1 1 0 Mpp10 protein Apt1 PF10351.9 EKX48345.1 - 2.5 6.9 12.3 3.1 6.5 12.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hid1 PF12722.7 EKX48345.1 - 3.2 5.8 9.4 4 5.5 9.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TFIIF_alpha PF05793.12 EKX48345.1 - 3.7 6.0 37.9 5 5.6 37.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SLC12 PF03522.15 EKX48345.1 - 5.6 5.9 8.7 7.4 5.5 8.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Suf PF05843.14 EKX48345.1 - 6 6.8 8.0 8.3 6.3 8.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4551 PF15087.6 EKX48345.1 - 6.6 5.4 4.8 8.1 5.1 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SAPS PF04499.15 EKX48345.1 - 7 5.3 12.7 9.4 4.9 12.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pes-10 PF07149.11 EKX48345.1 - 7.4 5.5 24.4 9.7 5.1 24.4 1.1 1 0 0 1 1 1 0 Pes-10 Caps_assemb_Wzi PF14052.6 EKX48346.1 - 0.057 12.5 0.0 0.081 12.0 0.0 1.1 1 0 0 1 1 1 0 Capsule assembly protein Wzi Pkinase PF00069.25 EKX48347.1 - 4.5e-51 173.7 0.0 4.7e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX48347.1 - 2.6e-34 118.7 0.0 3e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX48347.1 - 1.6e-06 27.2 0.1 0.00096 18.0 0.2 2.1 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 EKX48347.1 - 0.00068 19.6 0.0 0.0061 16.5 0.2 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX48347.1 - 0.0011 18.4 0.1 0.0014 18.0 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EKX48347.1 - 0.0087 15.7 1.4 0.062 12.9 0.3 2.1 1 1 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 EKX48347.1 - 0.025 14.2 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF2564 PF10819.8 EKX48347.1 - 0.16 12.3 0.0 0.31 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) EF-hand_1 PF00036.32 EKX48348.1 - 1.1e-28 96.6 8.8 9.5e-07 27.9 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EKX48348.1 - 2.9e-27 94.9 7.4 1.2e-14 54.5 2.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX48348.1 - 7.7e-24 81.5 4.8 5.6e-06 25.9 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EKX48348.1 - 5.3e-19 66.8 9.0 0.00013 21.3 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EKX48348.1 - 3.2e-16 58.9 15.0 4.2e-07 29.7 2.0 4.1 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 EKX48348.1 - 4e-07 30.3 0.1 3.3e-05 24.1 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 EKX48348.1 - 2.4e-06 27.4 4.0 4.3e-05 23.4 0.3 3.0 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 EKX48348.1 - 0.00033 20.6 0.6 0.083 12.8 0.0 2.7 1 1 2 3 3 3 1 Caleosin related protein SPARC_Ca_bdg PF10591.9 EKX48348.1 - 0.00037 20.8 3.9 0.01 16.1 0.4 2.3 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Armet PF10208.9 EKX48348.1 - 0.0051 16.7 0.1 0.18 11.8 0.0 2.4 2 0 0 2 2 2 1 Degradation arginine-rich protein for mis-folding MecA_N PF05223.11 EKX48348.1 - 0.027 14.8 0.1 0.084 13.2 0.1 1.8 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain EF-hand_11 PF08976.11 EKX48348.1 - 0.09 13.7 0.3 0.2 12.5 0.1 1.8 2 0 0 2 2 1 0 EF-hand domain Peptidase_S46 PF10459.9 EKX48348.1 - 0.1 11.3 0.7 0.12 11.0 0.7 1.1 1 0 0 1 1 1 0 Peptidase S46 EF-hand_10 PF14788.6 EKX48348.1 - 0.27 11.1 5.4 3.6 7.5 0.0 3.3 4 0 0 4 4 4 0 EF hand Alpha-amylase PF00128.24 EKX48349.1 - 2.7e-16 60.1 0.0 2e-13 50.6 0.1 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.18 EKX48349.1 - 8.6e-09 35.6 0.2 6.1e-08 32.9 0.0 2.4 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase_C PF02806.18 EKX48349.1 - 1e-05 25.9 0.0 5e-05 23.7 0.0 2.2 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Cellulase PF00150.18 EKX48349.1 - 0.076 12.4 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_70 PF02324.16 EKX48349.1 - 0.12 10.5 0.0 0.2 9.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 cNMP_binding PF00027.29 EKX48350.1 - 3.5e-35 119.9 0.6 5.7e-12 45.5 0.0 3.7 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain Pkinase PF00069.25 EKX48351.1 - 2.3e-08 33.8 0.0 9.6e-06 25.1 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Saf-Nte_pilin PF09460.10 EKX48351.1 - 0.062 13.3 0.6 28 4.7 0.1 3.3 3 0 0 3 3 3 0 Saf-pilin pilus formation protein PA PF02225.22 EKX48353.1 - 3.4e-09 36.6 0.1 1e-08 35.0 0.1 1.9 1 0 0 1 1 1 1 PA domain PDZ_2 PF13180.6 EKX48353.1 - 4.8e-08 33.2 0.0 9.8e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX48353.1 - 2.9e-07 30.8 0.1 8.5e-07 29.2 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX48353.1 - 3.4e-07 30.0 0.1 8.1e-07 28.8 0.1 1.7 1 0 0 1 1 1 1 PDZ domain zf-CpG_bind_C PF12269.8 EKX48353.1 - 0.25 11.1 2.8 0.13 12.0 0.4 1.7 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain Ribosomal_S21 PF01165.20 EKX48354.1 - 5.2e-08 32.5 0.9 5.2e-08 32.5 0.9 2.1 2 0 0 2 2 2 1 Ribosomal protein S21 LolB PF03550.14 EKX48354.1 - 0.11 12.5 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein LolB Beta_helix PF13229.6 EKX48355.1 - 0.033 14.1 0.0 0.085 12.7 0.0 1.5 1 1 0 1 1 1 0 Right handed beta helix region DUF2852 PF11014.8 EKX48356.1 - 0.51 10.5 4.4 0.67 10.1 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) Stathmin PF00836.19 EKX48356.1 - 2.6 8.0 15.5 1.7 8.6 11.0 1.9 1 1 1 2 2 2 0 Stathmin family Amidohydro_1 PF01979.20 EKX48357.1 - 0.093 12.0 0.4 2.2 7.5 0.3 2.2 2 0 0 2 2 2 0 Amidohydrolase family Cgr1 PF03879.14 EKX48357.1 - 6.5 7.2 13.2 4.9 7.6 1.5 2.5 2 0 0 2 2 2 0 Cgr1 family Zn_clus PF00172.18 EKX48359.1 - 4.7e-10 39.4 32.8 3.5e-06 27.0 10.9 2.8 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_19 PF14559.6 EKX48360.1 - 1.3e-06 28.8 0.4 0.047 14.2 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX48360.1 - 1.5e-05 25.4 7.1 1.2 10.2 0.1 5.8 5 1 1 6 6 6 2 Tetratricopeptide repeat NRDE-2 PF08424.10 EKX48360.1 - 1.8e-05 24.1 0.9 3.2e-05 23.2 0.9 1.5 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference zf-C3H1 PF10650.9 EKX48360.1 - 0.00017 21.2 2.3 0.00035 20.2 2.3 1.6 1 0 0 1 1 1 1 Putative zinc-finger domain HrpB1_HrpK PF09613.10 EKX48360.1 - 0.0035 17.0 0.7 0.24 11.1 0.0 3.1 3 0 0 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_4 PF07721.14 EKX48360.1 - 1.5 9.7 7.6 1.3 9.8 0.2 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat POTRA_2 PF08479.11 EKX48361.1 - 0.028 14.2 0.1 10 6.1 0.1 2.4 2 0 0 2 2 2 0 POTRA domain, ShlB-type REJ PF02010.15 EKX48362.1 - 1.6e-28 99.8 13.1 5.5e-28 97.9 13.1 1.9 1 0 0 1 1 1 1 REJ domain EGF_2 PF07974.13 EKX48362.1 - 0.0051 17.2 8.9 0.0051 17.2 8.9 3.9 4 0 0 4 4 4 2 EGF-like domain DSL PF01414.19 EKX48362.1 - 0.039 14.2 19.5 0.037 14.3 16.5 2.6 2 0 0 2 2 2 0 Delta serrate ligand EF-hand_7 PF13499.6 EKX48363.1 - 7.6e-20 71.1 5.9 5.1e-11 42.9 0.5 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EKX48363.1 - 2e-19 67.6 14.4 1.9e-05 23.9 0.1 5.0 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 EKX48363.1 - 1.8e-15 55.4 5.1 0.00081 19.1 0.0 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EKX48363.1 - 4e-15 54.5 6.7 0.0012 18.2 0.4 4.9 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EKX48363.1 - 1.6e-12 47.0 10.7 4.8e-07 29.5 0.2 4.5 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 EKX48363.1 - 3.3e-09 37.0 0.3 0.0041 17.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_10 PF14788.6 EKX48363.1 - 0.0041 16.9 2.5 0.66 9.9 0.2 2.7 2 1 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 EKX48363.1 - 0.1 12.9 0.5 0.46 10.8 0.1 2.2 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EKX48363.1 - 0.22 11.5 6.0 2.1 8.3 0.5 3.2 2 2 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand WD40 PF00400.32 EKX48364.1 - 8e-48 159.4 21.8 8.8e-09 35.9 0.4 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 EKX48364.1 - 9e-29 100.3 0.7 1.5e-28 99.6 0.7 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 EKX48364.1 - 2e-10 40.8 0.1 0.11 12.8 0.0 5.7 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Lysozyme_like PF13702.6 EKX48364.1 - 0.014 15.1 0.8 0.024 14.3 0.8 1.3 1 0 0 1 1 1 0 Lysozyme-like Nucleoporin_N PF08801.11 EKX48364.1 - 0.03 13.1 0.0 3.8 6.2 0.1 2.9 2 1 0 3 3 3 0 Nup133 N terminal like Nup160 PF11715.8 EKX48364.1 - 0.03 13.0 0.1 3.6 6.1 0.0 3.0 3 1 0 3 3 3 0 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.6 EKX48364.1 - 0.041 13.1 0.0 0.56 9.4 0.0 2.6 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus eIF2A PF08662.11 EKX48364.1 - 0.089 12.7 0.0 8 6.3 0.1 2.5 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EKX48364.1 - 0.18 11.1 0.0 24 4.1 0.0 2.7 2 1 0 2 2 2 0 WD40-like domain V-SNARE_C PF12352.8 EKX48365.1 - 2.2 8.7 7.8 2.9 8.3 1.0 3.4 2 1 1 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus PDZ_2 PF13180.6 EKX48366.1 - 5.1e-31 106.8 7.0 2.1e-13 50.4 0.3 4.5 5 0 0 5 5 5 3 PDZ domain PDZ_6 PF17820.1 EKX48366.1 - 1.2e-29 101.9 10.1 1.5e-13 50.3 0.1 4.2 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.24 EKX48366.1 - 3.1e-24 85.1 8.8 6.5e-08 32.8 0.2 3.6 3 0 0 3 3 3 3 PDZ domain C2 PF00168.30 EKX48366.1 - 7.6e-22 77.6 0.0 1.8e-13 50.7 0.0 3.3 3 0 0 3 3 3 2 C2 domain Tricorn_PDZ PF14685.6 EKX48366.1 - 6.3e-11 42.1 4.1 0.00066 19.6 0.1 4.0 3 0 0 3 3 3 3 Tricorn protease PDZ domain WW PF00397.26 EKX48366.1 - 1.6e-09 37.7 1.2 3.5e-09 36.6 1.2 1.6 1 0 0 1 1 1 1 WW domain ERM PF00769.19 EKX48366.1 - 0.0022 17.9 17.5 0.004 17.0 17.5 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family GRASP55_65 PF04495.14 EKX48366.1 - 0.0049 17.2 0.0 3 8.2 0.0 2.8 2 0 0 2 2 2 2 GRASP55/65 PDZ-like domain DUF2151 PF10221.9 EKX48366.1 - 4 5.9 12.8 6 5.3 12.8 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator zf-rbx1 PF12678.7 EKX48367.1 - 4e-06 27.0 4.1 1.2e-05 25.5 4.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain WWE PF02825.20 EKX48367.1 - 3.5e-05 24.3 0.8 0.069 13.8 1.0 3.0 2 1 0 2 2 2 2 WWE domain zf-RING_2 PF13639.6 EKX48367.1 - 0.0016 18.7 7.9 0.0034 17.7 7.9 1.5 1 0 0 1 1 1 1 Ring finger domain ComA PF02679.15 EKX48367.1 - 0.026 14.0 0.3 0.035 13.6 0.3 1.2 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) zf-C3HC4_2 PF13923.6 EKX48367.1 - 0.043 13.7 9.0 0.076 12.9 9.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EKX48367.1 - 0.043 13.7 8.0 0.076 12.9 8.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX48367.1 - 0.044 13.7 5.8 0.08 12.9 5.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain YabA PF06156.13 EKX48369.1 - 0.016 15.9 3.4 0.016 15.9 3.4 3.1 1 1 2 3 3 3 0 Initiation control protein YabA PH PF00169.29 EKX48369.1 - 0.028 14.9 0.0 0.057 13.9 0.0 1.5 1 0 0 1 1 1 0 PH domain DUF4047 PF13256.6 EKX48369.1 - 0.036 14.2 3.1 0.064 13.4 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) KinB_sensor PF16767.5 EKX48369.1 - 0.86 10.1 9.8 1.4 9.4 5.0 2.9 1 1 2 3 3 3 0 Sensor domain of alginate biosynthesis sensor protein KinB DUF1664 PF07889.12 EKX48369.1 - 1.2 9.1 8.3 2 8.5 2.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Cob_adeno_trans PF01923.18 EKX48369.1 - 1.4 9.0 10.4 3 8.0 9.8 1.8 1 1 1 2 2 2 0 Cobalamin adenosyltransferase HALZ PF02183.18 EKX48369.1 - 2.2 8.6 12.1 2.6 8.3 0.3 3.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF1515 PF07439.11 EKX48369.1 - 4.4 7.4 5.9 8.2 6.5 0.1 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1515) V_ATPase_I PF01496.19 EKX48369.1 - 7.1 4.4 9.5 8.7 4.1 9.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 EKX48369.1 - 9.3 5.2 19.3 9.5 5.2 17.7 1.6 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 EKX48369.1 - 9.7 5.4 15.3 16 4.7 15.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PP2C PF00481.21 EKX48370.1 - 1.3e-43 149.6 0.0 2.9e-42 145.1 0.0 2.0 1 1 1 2 2 2 2 Protein phosphatase 2C ABC_tran PF00005.27 EKX48372.1 - 6.3e-49 166.0 0.2 6.6e-25 88.2 0.0 3.9 3 2 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 EKX48372.1 - 2.3e-16 60.5 0.0 0.0084 16.0 0.0 4.2 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EKX48372.1 - 4e-16 59.1 2.4 1.2e-05 24.8 0.2 4.1 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.24 EKX48372.1 - 3.2e-08 33.4 0.2 8.6e-08 32.0 0.2 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 EKX48372.1 - 1.3e-07 32.4 6.2 0.0026 18.3 0.0 3.2 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 EKX48372.1 - 7.3e-07 28.8 0.1 0.052 13.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EKX48372.1 - 4e-06 27.2 0.0 0.14 12.5 0.0 3.5 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 EKX48372.1 - 4.4e-06 26.7 0.0 0.037 14.1 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_15 PF13175.6 EKX48372.1 - 4.5e-06 26.6 0.7 0.14 11.8 0.0 3.3 4 0 0 4 4 3 2 AAA ATPase domain AAA PF00004.29 EKX48372.1 - 5.8e-06 26.8 0.0 0.16 12.4 0.0 3.6 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX48372.1 - 1.3e-05 25.6 0.0 0.095 13.1 0.0 3.6 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 EKX48372.1 - 1.4e-05 25.1 0.0 0.08 12.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 EKX48372.1 - 2.7e-05 24.5 0.0 0.056 13.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EKX48372.1 - 3.4e-05 23.4 0.1 0.17 11.4 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 EKX48372.1 - 7e-05 23.0 0.2 0.48 10.6 0.0 3.0 2 1 0 3 3 2 2 AAA domain AAA_30 PF13604.6 EKX48372.1 - 9.3e-05 22.2 0.3 1.5 8.5 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 EKX48372.1 - 0.00011 22.8 0.0 0.54 10.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EKX48372.1 - 0.00011 22.5 0.0 0.47 10.9 0.0 2.7 2 0 0 2 2 2 2 RNA helicase SbcCD_C PF13558.6 EKX48372.1 - 0.00014 22.0 0.0 0.15 12.4 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 EKX48372.1 - 0.00017 21.6 0.1 0.61 10.0 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain MeaB PF03308.16 EKX48372.1 - 0.00047 19.2 0.3 0.71 8.8 0.1 2.6 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 EKX48372.1 - 0.0019 18.2 0.1 0.36 10.7 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_27 PF13514.6 EKX48372.1 - 0.0025 17.4 0.0 3.1 7.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 EKX48372.1 - 0.0026 17.0 0.0 1.9 7.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) DUF87 PF01935.17 EKX48372.1 - 0.0038 17.4 0.1 0.38 10.8 0.1 3.1 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_14 PF13173.6 EKX48372.1 - 0.0042 17.1 0.0 3.1 7.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EKX48372.1 - 0.0059 16.6 0.1 0.23 11.3 0.0 2.6 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EKX48372.1 - 0.0069 16.1 0.0 3 7.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain HEAT PF02985.22 EKX48372.1 - 0.0069 16.6 1.2 62 4.2 0.5 4.2 3 0 0 3 3 3 0 HEAT repeat NB-ARC PF00931.22 EKX48372.1 - 0.0077 15.4 0.1 0.6 9.2 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Dynamin_N PF00350.23 EKX48372.1 - 0.012 15.7 0.1 0.31 11.1 0.0 2.8 2 0 0 2 2 2 0 Dynamin family Roc PF08477.13 EKX48372.1 - 0.018 15.2 0.0 11 6.3 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 EKX48372.1 - 0.023 14.6 1.3 3.5 7.5 0.1 3.2 3 0 0 3 3 2 0 NTPase Zeta_toxin PF06414.12 EKX48372.1 - 0.029 13.6 0.1 1.5 8.0 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.14 EKX48372.1 - 0.039 14.0 0.7 29 4.6 0.0 3.8 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) CLP1_P PF16575.5 EKX48372.1 - 0.048 13.4 0.4 2.7 7.7 0.0 2.8 3 0 0 3 3 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Cytidylate_kin PF02224.18 EKX48372.1 - 0.056 13.2 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase PRK PF00485.18 EKX48372.1 - 0.066 13.0 0.0 4.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Mg_chelatase PF01078.21 EKX48372.1 - 0.073 12.4 0.4 31 3.9 0.0 3.4 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.9 EKX48372.1 - 0.089 12.5 0.0 11 5.8 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.17 EKX48372.1 - 0.094 12.4 0.7 24 4.6 0.1 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein Adeno_IVa2 PF02456.15 EKX48372.1 - 0.12 11.1 0.1 1.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein cobW PF02492.19 EKX48372.1 - 0.15 11.7 0.5 17 4.9 0.0 2.9 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Lipase_GDSL_3 PF14606.6 EKX48372.1 - 0.2 11.7 1.0 1.4 9.1 0.0 2.8 3 0 0 3 3 2 0 GDSL-like Lipase/Acylhydrolase family EF-hand_1 PF00036.32 EKX48374.1 - 8.2e-17 59.4 0.0 1.4e-07 30.5 0.0 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX48374.1 - 3e-14 51.7 0.1 8.8e-07 28.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EKX48374.1 - 1.5e-12 46.4 0.0 3.9e-05 23.0 0.0 2.1 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX48374.1 - 2.3e-10 40.8 0.1 5.7e-10 39.5 0.1 1.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EKX48374.1 - 4.7e-08 32.8 0.1 3.5e-05 23.6 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair PMBR PF09373.10 EKX48374.1 - 0.046 13.9 0.0 0.25 11.5 0.0 2.2 3 0 0 3 3 3 0 Pseudomurein-binding repeat DUF5122 PF17164.4 EKX48374.1 - 0.1 12.9 0.2 2.2 8.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5122) beta-propeller EF-hand_7 PF13499.6 EKX48375.1 - 1.4e-15 57.4 9.6 4.4e-11 43.1 2.0 4.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX48375.1 - 4.1e-11 41.6 8.3 0.0062 16.0 0.0 3.9 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EKX48375.1 - 2.1e-09 37.1 12.6 0.038 13.8 0.2 5.3 3 2 2 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.6 EKX48375.1 - 3.8e-09 35.7 9.3 0.018 14.9 1.7 3.8 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 EKX48375.1 - 0.00089 18.7 15.6 0.059 12.9 1.2 4.1 4 0 0 4 4 4 2 EF hand Caleosin PF05042.13 EKX48375.1 - 0.023 14.6 2.9 2.1 8.3 0.1 3.9 4 0 0 4 4 4 0 Caleosin related protein EF-hand_4 PF12763.7 EKX48375.1 - 0.03 14.3 2.1 7 6.7 0.2 2.9 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF3500 PF12006.8 EKX48375.1 - 0.062 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) OSTbeta PF15048.6 EKX48375.1 - 1 9.5 10.0 1.4 9.1 0.8 3.6 3 1 1 4 4 4 0 Organic solute transporter subunit beta protein DUF773 PF05600.12 EKX48376.1 - 1.2e-100 337.7 12.7 5.4e-88 295.9 6.7 2.3 1 1 1 2 2 2 2 CDK5 regulatory subunit-associated protein 3 T2SSF PF00482.23 EKX48376.1 - 0.08 12.9 0.9 0.23 11.4 0.1 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F DUF3618 PF12277.8 EKX48376.1 - 0.087 13.1 0.0 0.31 11.3 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) DUF4618 PF15397.6 EKX48376.1 - 0.21 11.0 11.1 0.024 14.1 2.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF16 PF01519.16 EKX48376.1 - 0.25 11.9 5.8 0.89 10.1 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 GAT PF03127.14 EKX48376.1 - 0.34 11.2 6.3 3.7 7.9 0.1 4.3 4 0 0 4 4 4 0 GAT domain DUF4404 PF14357.6 EKX48376.1 - 0.93 10.2 0.0 0.93 10.2 0.0 4.0 4 2 2 6 6 6 0 Domain of unknown function (DUF4404) ZapB PF06005.12 EKX48376.1 - 1.5 9.3 7.5 1.3 9.6 0.4 3.1 2 0 0 2 2 2 0 Cell division protein ZapB Glyco_transf_41 PF13844.6 EKX48377.1 - 3.3e-45 154.4 0.1 2.8e-44 151.3 0.1 2.0 1 1 1 2 2 2 1 Glycosyl transferase family 41 TPR_9 PF13371.6 EKX48377.1 - 1.6e-10 41.0 2.6 0.00019 21.5 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX48377.1 - 2.8e-08 33.2 9.1 0.0012 18.8 0.0 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX48377.1 - 2.9e-07 30.1 0.7 0.00025 20.7 0.1 3.1 2 1 1 3 3 3 2 TPR repeat TPR_14 PF13428.6 EKX48377.1 - 8.9e-07 29.2 5.8 0.00089 19.9 0.1 4.8 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX48377.1 - 1.1e-06 29.1 6.1 0.0079 16.7 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX48377.1 - 2.8e-06 27.5 1.0 2.8e-06 27.5 1.0 2.6 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX48377.1 - 3.7e-06 26.7 1.4 0.0033 17.5 0.0 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX48377.1 - 1.7e-05 24.4 5.9 0.001 18.8 0.0 4.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX48377.1 - 7.5e-05 23.3 7.5 0.03 15.0 0.2 3.1 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX48377.1 - 0.0003 21.0 0.0 0.97 10.0 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX48377.1 - 0.0021 18.0 0.3 0.92 9.7 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.9 EKX48377.1 - 0.0034 17.1 1.5 0.0053 16.5 1.5 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 EKX48377.1 - 0.006 17.1 6.6 0.34 11.6 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX48377.1 - 0.054 13.4 1.7 3.7 7.5 0.5 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Ion_trans_2 PF07885.16 EKX48378.1 - 8.2e-09 35.3 2.9 8.2e-09 35.3 2.9 1.9 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 EKX48378.1 - 0.0029 16.9 13.0 0.035 13.4 13.0 2.3 1 1 0 1 1 1 1 Ion transport protein NPV_P10 PF05531.12 EKX48378.1 - 0.015 15.7 1.2 0.25 11.8 0.7 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Csm1_N PF18504.1 EKX48378.1 - 0.18 12.2 4.4 0.4 11.1 4.4 1.6 1 0 0 1 1 1 0 Csm1 N-terminal domain SK_channel PF03530.14 EKX48378.1 - 0.73 9.8 7.2 4.5 7.3 7.2 2.3 1 1 0 1 1 1 0 Calcium-activated SK potassium channel DUF16 PF01519.16 EKX48378.1 - 1.1 9.8 4.4 0.8 10.2 2.4 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 XhlA PF10779.9 EKX48378.1 - 1.6 9.0 4.4 0.96 9.7 1.0 2.3 2 0 0 2 2 2 0 Haemolysin XhlA Sec3_C_2 PF15278.6 EKX48379.1 - 7.3 7.0 9.4 6.4 7.2 0.1 3.4 3 1 1 4 4 4 0 Sec3 exocyst complex subunit PrmA PF06325.13 EKX48380.1 - 7.5e-54 183.1 0.0 2.7e-52 178.0 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EKX48380.1 - 0.0032 17.0 0.0 0.1 12.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase small domain Secretin_N PF03958.17 EKX48381.1 - 0.14 12.6 0.0 0.45 11.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial type II/III secretion system short domain U-box PF04564.15 EKX48382.1 - 5e-18 65.1 0.0 1.2e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 U-box domain USP7_C2 PF14533.6 EKX48382.1 - 1.1e-07 31.8 0.1 9.3e-07 28.8 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal zf-Nse PF11789.8 EKX48382.1 - 0.0012 18.6 0.0 0.0031 17.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF111 PF01969.17 EKX48382.1 - 0.18 10.9 0.1 0.29 10.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF111 Zn_clus PF00172.18 EKX48384.1 - 2.5e-08 33.9 12.9 3.7e-08 33.4 12.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Carb_anhydrase PF00194.21 EKX48385.1 - 6.3e-28 98.0 0.3 1.3e-13 51.1 0.1 2.3 1 1 1 2 2 2 2 Eukaryotic-type carbonic anhydrase Pkinase PF00069.25 EKX48387.1 - 7.6e-47 159.9 0.1 8.5e-47 159.7 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX48387.1 - 2.5e-35 122.0 0.1 2.8e-35 121.8 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX48387.1 - 1.8e-05 23.8 1.1 0.011 14.5 0.1 2.1 1 1 1 2 2 2 2 Fungal protein kinase Haspin_kinase PF12330.8 EKX48387.1 - 0.00014 20.9 0.1 0.00043 19.3 0.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EKX48387.1 - 0.00018 20.9 0.0 0.00061 19.2 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.11 EKX48387.1 - 0.058 12.4 0.1 0.068 12.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APP_Cu_bd PF12924.7 EKX48387.1 - 0.13 13.0 0.0 0.24 12.2 0.0 1.3 1 0 0 1 1 1 0 Copper-binding of amyloid precursor, CuBD APH PF01636.23 EKX48387.1 - 0.13 12.2 0.0 0.66 9.8 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EKX48387.1 - 0.14 11.5 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_14 PF13428.6 EKX48388.1 - 0.00018 22.0 3.0 0.029 15.2 0.5 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX48388.1 - 0.0039 17.2 4.0 0.077 13.2 0.8 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX48388.1 - 0.0056 17.0 0.5 0.07 13.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX48388.1 - 0.013 16.0 4.9 0.068 13.7 1.5 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX48388.1 - 0.04 14.2 1.6 0.22 11.8 1.6 2.3 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 EKX48388.1 - 0.16 11.8 2.1 1.6 8.6 0.8 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat ImpA_N PF06812.12 EKX48388.1 - 0.17 12.0 0.5 0.38 10.9 0.5 1.6 1 1 0 1 1 1 0 ImpA, N-terminal, type VI secretion system fn3 PF00041.21 EKX48389.1 - 0.0058 17.0 0.6 0.11 12.9 0.0 3.4 5 0 0 5 5 5 1 Fibronectin type III domain PLRV_ORF5 PF01690.17 EKX48390.1 - 0.02 13.6 0.2 0.031 13.0 0.2 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein OATP PF03137.20 EKX48390.1 - 0.034 12.4 0.0 0.034 12.4 0.0 2.2 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family START PF01852.19 EKX48391.1 - 4.9e-13 49.0 0.2 6.1e-13 48.7 0.2 1.1 1 0 0 1 1 1 1 START domain DNA_photolyase PF00875.18 EKX48392.1 - 0.0005 20.1 0.1 0.00085 19.4 0.1 1.3 1 0 0 1 1 1 1 DNA photolyase TIG PF01833.24 EKX48395.1 - 7.4e-37 125.3 30.3 9.7e-08 32.0 0.4 9.8 10 1 0 10 10 10 6 IPT/TIG domain Kelch_4 PF13418.6 EKX48395.1 - 1.3e-07 31.5 1.3 0.2 11.7 0.2 4.7 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 EKX48395.1 - 1e-06 28.2 0.0 0.021 14.4 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 EKX48395.1 - 8.3e-05 22.7 0.9 0.68 10.3 0.0 4.6 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.6 EKX48395.1 - 0.045 13.7 5.6 4.8 7.3 0.1 4.1 4 0 0 4 4 4 0 Kelch motif Pkinase PF00069.25 EKX48396.1 - 3.6e-43 147.8 0.0 4.1e-43 147.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX48396.1 - 4.2e-31 108.2 0.0 4.9e-31 107.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX48396.1 - 6.9e-08 32.1 0.1 8.3e-08 31.8 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EKX48396.1 - 0.0073 15.3 0.1 0.01 14.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EKX48396.1 - 0.014 14.7 0.0 0.071 12.4 0.0 1.9 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 EKX48396.1 - 0.02 14.8 0.1 1.1 9.1 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX48396.1 - 0.076 11.8 0.0 0.093 11.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase EF-hand_7 PF13499.6 EKX48397.1 - 2.1e-10 40.9 0.1 1.5e-07 31.8 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX48397.1 - 2.2e-07 30.3 0.1 0.049 13.6 0.0 3.6 3 1 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 EKX48397.1 - 4.4e-06 26.4 1.4 6 6.8 0.0 4.5 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 EKX48397.1 - 0.00049 19.5 0.1 2.4 7.9 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 EKX48397.1 - 0.025 14.5 0.1 0.65 10.0 0.1 2.3 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Ank PF00023.30 EKX48398.1 - 1.5e-15 56.9 3.0 1.1e-09 38.3 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EKX48398.1 - 7.4e-15 55.3 0.4 2.5e-07 31.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX48398.1 - 1.8e-13 50.7 1.1 1.1e-10 41.8 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX48398.1 - 1.9e-13 50.4 0.8 3.1e-10 40.1 0.2 2.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX48398.1 - 2.9e-13 48.7 0.5 4.8e-06 26.5 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat PHO4 PF01384.20 EKX48399.1 - 8.8e-109 363.6 20.9 1e-108 363.4 20.9 1.0 1 0 0 1 1 1 1 Phosphate transporter family DPM3 PF08285.11 EKX48399.1 - 0.34 11.1 1.4 1.1 9.6 0.2 2.5 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) TPR_17 PF13431.6 EKX48400.1 - 2.3e-12 46.4 6.7 0.00098 19.3 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX48400.1 - 7.2e-09 36.1 4.9 0.58 10.8 0.2 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX48400.1 - 8.3e-09 35.0 12.0 4.7e-05 23.3 0.2 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX48400.1 - 3.4e-08 33.0 13.8 1.7e-05 24.4 1.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX48400.1 - 7.8e-08 32.5 8.9 0.00057 20.1 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX48400.1 - 4e-07 30.4 6.3 0.21 12.1 0.2 5.0 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX48400.1 - 4.1e-07 29.6 17.2 0.0029 17.5 0.1 5.9 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX48400.1 - 7.3e-07 28.8 17.8 0.00011 22.0 0.8 7.2 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX48400.1 - 8.8e-05 23.0 12.1 1.6 9.7 0.2 6.9 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX48400.1 - 0.0021 17.9 18.6 0.016 15.0 0.9 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX48400.1 - 0.0058 16.3 3.4 3.9 7.2 0.0 4.9 4 1 1 5 5 5 1 TPR repeat TPR_9 PF13371.6 EKX48400.1 - 0.026 14.7 4.7 0.19 11.9 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX48400.1 - 0.044 14.4 5.5 10 7.0 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat DZR PF12773.7 EKX48400.1 - 1.2 9.2 4.8 9.6 6.3 2.4 2.6 2 0 0 2 2 2 0 Double zinc ribbon EF-hand_8 PF13833.6 EKX48401.1 - 1.2e-09 37.8 0.0 4e-09 36.2 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX48401.1 - 1.2e-06 27.6 0.7 0.0039 16.6 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX48401.1 - 3.9e-06 27.2 0.1 1.4e-05 25.5 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX48401.1 - 2.3e-05 24.0 1.3 0.0009 19.0 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 EKX48401.1 - 0.0023 17.3 0.6 0.008 15.6 0.1 2.3 2 0 0 2 2 2 1 EF hand NrfD_2 PF14589.6 EKX48401.1 - 0.092 12.7 6.4 2.2 8.2 2.6 2.3 2 0 0 2 2 2 0 Polysulfide reductase Acp26Ab PF05777.12 EKX48401.1 - 0.097 13.3 0.4 25 5.6 0.2 3.0 2 0 0 2 2 2 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) DUF2207 PF09972.9 EKX48401.1 - 0.24 10.1 9.5 5.2 5.7 0.1 3.8 4 0 0 4 4 4 0 Predicted membrane protein (DUF2207) DUF2975 PF11188.8 EKX48401.1 - 1.9 8.4 7.1 0.79 9.6 2.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Fer4_8 PF13183.6 EKX48403.1 - 0.97 9.9 4.5 4.9 7.7 0.6 3.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Glutaredoxin PF00462.24 EKX48404.1 - 8.9e-17 61.1 0.0 1.7e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Glyoxalase PF00903.25 EKX48404.1 - 1e-10 41.9 0.0 0.00093 19.4 0.0 2.9 3 1 0 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily GST_N_3 PF13417.6 EKX48404.1 - 0.00021 21.6 0.0 0.035 14.5 0.0 2.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 EKX48404.1 - 0.012 16.1 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain TraF PF13728.6 EKX48404.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein DUF836 PF05768.14 EKX48404.1 - 0.18 12.3 0.0 0.4 11.1 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Peptidase_M24 PF00557.24 EKX48405.1 - 3.4e-59 200.0 0.1 4.5e-59 199.6 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EKX48405.1 - 2.3e-26 91.9 0.0 4.3e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain RCC1_2 PF13540.6 EKX48406.1 - 8.4e-21 73.3 26.8 2.3e-06 27.2 0.4 4.2 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat Fig1 PF12351.8 EKX48406.1 - 0.016 15.1 1.6 1.7 8.6 0.0 3.1 1 1 2 3 3 3 0 Ca2+ regulator and membrane fusion protein Fig1 TraF_2 PF13729.6 EKX48406.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein DHC_N1 PF08385.12 EKX48407.1 - 4.9e-176 586.7 6.2 4.9e-176 586.7 6.2 3.4 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 EKX48407.1 - 6e-138 459.3 0.0 7.7e-136 452.4 0.0 3.5 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EKX48407.1 - 1.3e-117 393.3 7.7 1.3e-117 393.3 7.7 3.5 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 MT PF12777.7 EKX48407.1 - 3.6e-98 328.8 17.9 9.4e-98 327.4 17.9 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_8 PF12780.7 EKX48407.1 - 8.1e-92 307.2 0.1 2.2e-91 305.8 0.1 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EKX48407.1 - 1.9e-87 293.4 0.0 7.4e-87 291.4 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EKX48407.1 - 9.5e-84 279.9 5.2 9.5e-84 279.9 5.2 2.7 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 EKX48407.1 - 2.7e-67 225.8 1.7 2.2e-63 213.1 0.2 3.8 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EKX48407.1 - 1.3e-44 151.9 0.0 3.1e-44 150.7 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EKX48407.1 - 1.4e-36 125.2 0.0 8.1e-32 109.8 0.0 3.7 3 0 0 3 3 2 2 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 EKX48407.1 - 2.7e-27 94.9 0.1 1.2e-26 92.8 0.1 2.3 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 EKX48407.1 - 5.4e-27 94.4 0.2 3.7e-26 91.7 0.1 2.7 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EKX48407.1 - 1e-20 74.2 0.0 5e-11 42.8 0.0 5.4 5 0 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EKX48407.1 - 1.7e-07 31.8 1.0 0.095 13.1 0.0 5.6 5 0 0 5 5 4 2 AAA ATPase domain AAA_18 PF13238.6 EKX48407.1 - 6.7e-07 29.9 1.5 0.09 13.3 0.0 4.7 4 0 0 4 4 3 2 AAA domain AAA PF00004.29 EKX48407.1 - 1.4e-06 28.8 0.4 1.1 9.6 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EKX48407.1 - 2.7e-05 24.5 1.7 4.7 7.5 0.0 5.2 5 0 0 5 5 3 1 AAA domain RNA_helicase PF00910.22 EKX48407.1 - 9.8e-05 22.7 0.1 0.9 10.0 0.0 4.1 3 0 0 3 3 3 1 RNA helicase AAA_30 PF13604.6 EKX48407.1 - 0.00015 21.6 3.6 0.52 10.0 0.0 4.3 4 0 0 4 4 3 1 AAA domain AAA_14 PF13173.6 EKX48407.1 - 0.00059 19.9 0.1 1.1 9.3 0.0 4.1 4 0 0 4 4 3 1 AAA domain AAA_19 PF13245.6 EKX48407.1 - 0.001 19.4 1.7 1.8 8.9 0.0 4.7 4 0 0 4 4 4 1 AAA domain ABC_tran PF00005.27 EKX48407.1 - 0.001 19.6 0.1 0.54 10.8 0.0 3.7 3 0 0 3 3 2 1 ABC transporter Rad17 PF03215.15 EKX48407.1 - 0.0037 17.2 0.0 0.18 11.7 0.0 3.0 2 0 0 2 2 2 1 Rad17 P-loop domain Viral_helicase1 PF01443.18 EKX48407.1 - 0.013 15.2 0.7 2.7 7.6 0.0 3.4 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 EKX48407.1 - 0.017 14.9 0.1 29 4.3 0.0 4.0 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 EKX48407.1 - 0.023 14.6 0.0 21 5.0 0.0 3.6 3 0 0 3 3 3 0 NACHT domain AAA_28 PF13521.6 EKX48407.1 - 0.027 14.7 0.2 40 4.4 0.0 3.9 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 EKX48407.1 - 0.03 14.5 1.0 2 8.7 0.1 3.9 4 0 0 4 4 2 0 Ras of Complex, Roc, domain of DAPkinase Sigma54_activat PF00158.26 EKX48407.1 - 0.056 13.2 0.0 39 3.9 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain DnaB_2 PF07261.11 EKX48407.1 - 0.061 13.1 0.0 22 4.9 0.0 3.4 2 0 0 2 2 2 0 Replication initiation and membrane attachment AAA_33 PF13671.6 EKX48407.1 - 0.07 13.3 1.6 33 4.6 0.0 4.2 4 0 0 4 4 3 0 AAA domain T2SSE PF00437.20 EKX48407.1 - 0.083 11.9 0.0 5.1 6.1 0.0 3.3 3 0 0 3 3 3 0 Type II/IV secretion system protein TsaE PF02367.17 EKX48407.1 - 0.11 12.5 0.9 15 5.6 0.0 3.6 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE kleA_kleC PF17383.2 EKX48407.1 - 0.39 11.1 4.6 4.7 7.6 4.9 2.7 2 0 0 2 2 1 0 Uncharacterized KorC regulated protein A DUF4407 PF14362.6 EKX48407.1 - 7.1 5.9 15.7 0.4 10.0 2.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CCDC53 PF10152.9 EKX48407.1 - 9.8 6.6 7.6 21 5.5 0.0 3.2 3 0 0 3 3 2 0 Subunit CCDC53 of WASH complex Sad1_UNC PF07738.13 EKX48408.1 - 8e-20 71.2 0.0 1.2e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Peptidase_M16_C PF05193.21 EKX48409.1 - 3.6e-29 102.1 0.0 5.9e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EKX48409.1 - 2.8e-25 89.0 0.0 5.8e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) NUDIX PF00293.28 EKX48410.1 - 1.3e-07 31.7 0.0 1.3e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Ephrin_rec_like PF07699.13 EKX48411.1 - 2.2e-24 84.9 27.5 6.2e-13 48.3 7.8 4.6 3 0 0 3 3 3 2 Putative ephrin-receptor like DUF3456 PF11938.8 EKX48411.1 - 1.8e-07 31.8 0.5 1.8e-07 31.8 0.5 3.6 4 1 0 4 4 4 1 TLR4 regulator and MIR-interacting MSAP EF-hand_7 PF13499.6 EKX48411.1 - 1.6e-05 25.2 2.8 4.9e-05 23.7 2.8 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX48411.1 - 0.0016 17.9 1.3 0.3 10.7 0.0 3.0 2 0 0 2 2 2 1 EF hand DUF4215 PF13948.6 EKX48411.1 - 0.0023 18.3 6.4 0.0023 18.3 6.4 10.1 7 3 2 10 10 9 1 Domain of unknown function (DUF4215) EF-hand_6 PF13405.6 EKX48411.1 - 0.0039 17.0 2.6 0.14 12.1 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain SapB_1 PF05184.15 EKX48411.1 - 0.082 13.0 2.6 0.74 9.9 0.7 3.3 2 0 0 2 2 2 0 Saposin-like type B, region 1 EF-hand_5 PF13202.6 EKX48411.1 - 0.23 11.0 1.0 0.88 9.2 0.1 2.4 2 0 0 2 2 2 0 EF hand EGF_MSP1_1 PF12946.7 EKX48411.1 - 2 8.6 79.9 0.62 10.2 1.5 13.4 13 0 0 13 13 13 0 MSP1 EGF domain 1 Mucin PF01456.17 EKX48411.1 - 2.2 8.2 32.3 0.22 11.5 27.1 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein FSA_C PF10479.9 EKX48411.1 - 4.1 5.4 12.1 8.3 4.4 12.1 1.4 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SHIRT PF18655.1 EKX48412.1 - 0.065 13.8 0.1 0.12 13.0 0.1 1.5 1 1 0 1 1 1 0 SHIRT domain ADH_N PF08240.12 EKX48413.1 - 1.5e-26 92.4 5.7 3.3e-26 91.3 5.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EKX48413.1 - 1.5e-19 70.3 0.6 3.2e-19 69.2 0.6 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EKX48413.1 - 1.1e-07 31.3 0.5 2.1e-07 30.5 0.5 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EKX48413.1 - 4.3e-06 26.2 0.2 6.6e-06 25.6 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 EKX48413.1 - 0.0021 19.1 0.0 0.0034 18.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.15 EKX48413.1 - 0.0044 17.2 0.8 0.008 16.4 0.8 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Glu_dehyd_C PF16912.5 EKX48413.1 - 0.023 14.2 0.9 0.037 13.5 0.9 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Glyco_trans_1_4 PF13692.6 EKX48413.1 - 0.066 13.6 0.3 0.14 12.6 0.3 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 IGFBP PF00219.18 EKX48413.1 - 0.083 13.6 3.7 0.19 12.4 3.7 1.5 1 0 0 1 1 1 0 Insulin-like growth factor binding protein GTP_EFTU PF00009.27 EKX48415.1 - 1.8e-53 181.0 0.0 3.3e-53 180.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EKX48415.1 - 1.2e-16 60.5 0.0 2.7e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 EKX48415.1 - 5.2e-08 33.0 0.2 1.9e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EKX48415.1 - 5.5e-07 29.9 0.1 2.3e-06 27.9 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 SRPRB PF09439.10 EKX48415.1 - 0.0043 16.5 0.0 0.0092 15.4 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 EKX48415.1 - 0.0089 16.1 0.0 0.23 11.5 0.0 2.3 1 1 1 2 2 2 1 Dynamin family Septin PF00735.18 EKX48415.1 - 0.025 13.9 0.1 0.042 13.1 0.1 1.3 1 0 0 1 1 1 0 Septin AIG1 PF04548.16 EKX48415.1 - 0.067 12.5 0.0 0.17 11.2 0.0 1.6 2 0 0 2 2 2 0 AIG1 family Roc PF08477.13 EKX48415.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Papo_T_antigen PF02380.15 EKX48417.1 - 0.093 12.9 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 T-antigen specific domain Herpes_UL73 PF03554.13 EKX48417.1 - 1.2 9.2 4.1 21 5.2 0.3 2.4 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein Mannosyl_trans4 PF15971.5 EKX48418.1 - 0.11 12.4 0.5 0.18 11.6 0.5 1.4 1 0 0 1 1 1 0 DolP-mannose mannosyltransferase Sel1 PF08238.12 EKX48419.1 - 0.1 13.3 1.2 6.9 7.5 0.2 2.9 2 1 0 2 2 2 0 Sel1 repeat LMF1 PF06762.14 EKX48421.1 - 3.2e-75 253.9 23.2 2.3e-57 195.1 5.7 3.4 3 1 1 4 4 4 2 Lipase maturation factor MitoNEET_N PF10660.9 EKX48421.1 - 9.6e-05 22.3 0.1 0.00029 20.8 0.1 1.8 1 0 0 1 1 1 1 Iron-containing outer mitochondrial membrane protein N-terminus AAA PF00004.29 EKX48423.1 - 8.5e-35 120.1 0.1 8.6e-34 116.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EKX48423.1 - 5.8e-10 39.1 0.2 7e-09 35.6 0.1 2.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EKX48423.1 - 2.8e-06 27.8 0.1 1.6e-05 25.4 0.0 2.2 2 2 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EKX48423.1 - 7.4e-06 26.0 0.1 0.00019 21.4 0.1 3.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EKX48423.1 - 1.5e-05 25.0 0.0 2.5e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EKX48423.1 - 5.3e-05 23.5 0.2 0.007 16.6 0.1 2.9 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 EKX48423.1 - 0.0003 21.0 0.0 0.0008 19.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EKX48423.1 - 0.00034 20.8 0.0 0.00072 19.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.12 EKX48423.1 - 0.00038 19.8 0.0 0.00087 18.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Rad17 PF03215.15 EKX48423.1 - 0.00043 20.3 0.0 0.00086 19.3 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain NB-ARC PF00931.22 EKX48423.1 - 0.00073 18.8 0.0 0.012 14.9 0.0 2.4 1 1 1 2 2 2 1 NB-ARC domain AAA_18 PF13238.6 EKX48423.1 - 0.0023 18.5 0.0 0.019 15.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EKX48423.1 - 0.0024 17.7 0.0 0.004 16.9 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 EKX48423.1 - 0.0036 17.7 0.0 0.015 15.8 0.0 2.1 3 0 0 3 3 2 1 AAA domain Sigma54_activat PF00158.26 EKX48423.1 - 0.0047 16.6 0.0 0.11 12.2 0.0 2.5 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_lid_3 PF17862.1 EKX48423.1 - 0.0057 16.4 0.0 0.021 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA+ lid domain ABC_tran PF00005.27 EKX48423.1 - 0.011 16.2 0.1 0.097 13.2 0.1 2.4 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 EKX48423.1 - 0.012 15.5 0.1 0.065 13.2 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 EKX48423.1 - 0.016 14.7 0.0 0.18 11.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 EKX48423.1 - 0.016 15.4 0.0 0.035 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EKX48423.1 - 0.028 14.8 0.0 0.067 13.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 EKX48423.1 - 0.034 13.5 0.1 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EKX48423.1 - 0.038 14.0 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 EKX48423.1 - 0.047 13.8 0.1 1.1 9.4 0.0 3.0 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 EKX48423.1 - 0.053 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 EKX48423.1 - 0.068 13.3 0.1 0.27 11.3 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase IstB_IS21 PF01695.17 EKX48423.1 - 0.078 12.7 0.0 0.22 11.2 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 EKX48423.1 - 0.11 11.7 0.0 0.28 10.3 0.0 1.7 1 1 1 2 2 2 0 TIP49 P-loop domain AAA_30 PF13604.6 EKX48423.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 EKX48423.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Deoxynucleoside kinase TPR_12 PF13424.6 EKX48424.1 - 0.0036 17.6 0.1 0.0094 16.2 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX48424.1 - 0.0099 15.9 0.2 0.022 14.8 0.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX48424.1 - 0.04 13.8 0.1 0.093 12.6 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 EKX48424.1 - 0.064 13.9 0.3 0.17 12.6 0.3 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3283 PF11686.8 EKX48424.1 - 0.091 12.6 2.5 0.28 11.1 2.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3283) TPR_1 PF00515.28 EKX48424.1 - 0.095 12.6 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat CDC37_N PF03234.14 EKX48424.1 - 0.33 11.8 10.2 0.035 15.0 4.8 2.1 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding EGF_2 PF07974.13 EKX48425.1 - 8.5e-14 51.6 117.8 5e-05 23.6 17.0 7.3 4 3 4 8 8 8 5 EGF-like domain DSL PF01414.19 EKX48425.1 - 2.6e-13 50.0 112.5 1.1e-05 25.6 21.6 5.0 4 1 1 5 5 5 4 Delta serrate ligand EGF PF00008.27 EKX48425.1 - 6e-08 32.8 78.8 0.0002 21.6 8.1 5.7 5 0 0 5 5 5 4 EGF-like domain Laminin_EGF PF00053.24 EKX48425.1 - 0.0014 18.7 98.1 0.49 10.6 26.3 5.5 1 1 4 5 5 5 2 Laminin EGF domain hEGF PF12661.7 EKX48425.1 - 0.079 13.6 6.4 0.079 13.6 6.4 8.2 7 2 0 8 8 8 0 Human growth factor-like EGF tRNA-synt_2 PF00152.20 EKX48426.1 - 8.1e-41 140.1 0.0 9.1e-29 100.5 0.0 2.4 1 1 1 2 2 2 2 tRNA synthetases class II (D, K and N) NifU PF01106.17 EKX48426.1 - 5.5e-32 109.7 1.1 8.5e-25 86.7 0.2 2.6 2 0 0 2 2 2 2 NifU-like domain tRNA-synt_2d PF01409.20 EKX48426.1 - 2.1e-09 37.2 0.2 2.5e-08 33.7 0.2 2.1 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 EKX48426.1 - 1.7e-07 31.1 0.0 3.9e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Pyr_redox_2 PF07992.14 EKX48427.1 - 6.8e-06 25.5 0.1 2.3e-05 23.8 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EKX48427.1 - 0.071 13.1 0.0 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.14 EKX48427.1 - 0.096 11.4 0.0 0.76 8.4 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein PCIF1_WW PF12237.8 EKX48430.1 - 1.6e-09 37.7 0.0 1.9e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain CRR7 PF12095.8 EKX48432.1 - 1.1 9.7 4.0 1.9 9.0 1.3 2.4 3 0 0 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 MAT1 PF06391.13 EKX48432.1 - 2.2 8.1 9.6 2.3 8.0 8.1 1.7 1 1 1 2 2 2 0 CDK-activating kinase assembly factor MAT1 Pkinase PF00069.25 EKX48434.1 - 3.2e-43 148.0 0.0 5e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX48434.1 - 7.2e-43 146.7 0.0 1.1e-42 146.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 EKX48434.1 - 1.9e-10 41.0 1.9 2.6e-05 24.6 0.7 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX48434.1 - 2.7e-08 32.8 5.6 0.099 12.2 0.2 3.7 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EKX48434.1 - 1.6e-07 30.7 7.0 0.13 12.3 0.1 3.6 3 0 0 3 3 3 3 EF-hand domain Pkinase_fungal PF17667.1 EKX48434.1 - 3.1e-05 22.9 0.0 4.6e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase EF-hand_5 PF13202.6 EKX48434.1 - 0.014 14.8 4.9 0.1 12.2 0.3 3.4 3 0 0 3 3 3 0 EF hand TipE PF16972.5 EKX48434.1 - 0.062 12.5 0.0 0.09 11.9 0.0 1.1 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE Kdo PF06293.14 EKX48434.1 - 0.12 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_8 PF13833.6 EKX48434.1 - 0.21 11.5 0.6 5.1 7.0 0.1 2.7 2 0 0 2 2 2 0 EF-hand domain pair Patched PF02460.18 EKX48435.1 - 0.028 12.5 0.0 0.029 12.5 0.0 1.0 1 0 0 1 1 1 0 Patched family Patched PF02460.18 EKX48436.1 - 2.6e-59 201.1 4.7 2.3e-47 161.7 0.1 2.0 1 1 1 2 2 2 2 Patched family Sterol-sensing PF12349.8 EKX48436.1 - 4.2e-12 46.1 0.2 4.2e-12 46.1 0.2 3.5 2 2 1 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation FliX PF10768.9 EKX48436.1 - 0.025 15.1 0.1 0.042 14.4 0.1 1.2 1 0 0 1 1 1 0 Class II flagellar assembly regulator DUF2809 PF10990.8 EKX48436.1 - 0.14 12.8 8.2 0.1 13.3 4.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2809) Goodbye PF17109.5 EKX48437.1 - 0.13 12.7 2.1 1.3 9.5 0.1 3.7 3 0 0 3 3 3 0 fungal STAND N-terminal Goodbye domain SlyX PF04102.12 EKX48437.1 - 0.77 10.4 0.0 0.77 10.4 0.0 8.5 7 2 2 9 9 9 0 SlyX EXOSC1 PF10447.9 EKX48437.1 - 5.3 7.7 7.4 4.5 7.9 1.3 3.6 3 0 0 3 3 3 0 Exosome component EXOSC1/CSL4 Arm PF00514.23 EKX48438.1 - 1.3e-11 44.1 5.3 0.0047 16.9 0.0 6.6 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EKX48438.1 - 9e-11 41.1 3.2 0.087 13.1 0.1 4.8 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.6 EKX48438.1 - 4.7e-10 39.7 0.8 0.0013 19.1 0.2 3.5 2 1 2 4 4 4 3 HEAT repeats Cnd1 PF12717.7 EKX48438.1 - 1.8e-05 24.8 0.7 0.044 13.8 0.0 2.8 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EKX48438.1 - 0.00019 21.9 2.2 0.095 13.2 0.4 3.3 4 0 0 4 4 4 2 HEAT-like repeat Proteasom_PSMB PF10508.9 EKX48438.1 - 0.01 14.3 1.9 1.3 7.5 0.1 2.9 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit ACT_7 PF13840.6 EKX48438.1 - 0.019 14.8 0.1 0.044 13.6 0.1 1.6 1 0 0 1 1 1 0 ACT domain DUF3361 PF11841.8 EKX48438.1 - 0.02 14.8 1.0 0.1 12.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) V-ATPase_H_N PF03224.14 EKX48438.1 - 0.031 13.6 0.6 1.8 7.8 0.1 2.4 1 1 1 2 2 2 0 V-ATPase subunit H ParcG PF10274.9 EKX48438.1 - 0.033 14.3 0.1 0.16 12.1 0.0 2.1 2 0 0 2 2 2 0 Parkin co-regulated protein DUF4924 PF16271.5 EKX48438.1 - 0.077 13.0 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4924) CTNNBL PF08216.11 EKX48438.1 - 0.095 12.9 0.4 4.4 7.5 0.0 3.5 4 1 1 5 5 5 0 Catenin-beta-like, Arm-motif containing nuclear Drf_GBD PF06371.13 EKX48438.1 - 0.11 12.0 1.6 2.1 7.9 0.6 2.3 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain RICTOR_V PF14668.6 EKX48438.1 - 0.12 12.6 0.2 12 6.2 0.1 2.8 2 1 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 Sec7_N PF12783.7 EKX48438.1 - 0.33 10.8 2.0 24 4.8 0.1 3.0 2 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Peptidase_M1 PF01433.20 EKX48439.1 - 4.1e-42 144.2 1.8 1.8e-40 138.9 1.8 2.4 1 1 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 EKX48439.1 - 2.5e-21 75.8 1.1 1.1e-20 73.8 0.1 2.6 3 1 0 3 3 3 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 EKX48439.1 - 2.8e-16 60.2 0.3 8.3e-15 55.5 0.0 2.3 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Aminopep PF10023.9 EKX48439.1 - 0.015 14.7 1.3 0.054 12.8 1.3 1.9 1 1 0 1 1 1 0 Putative aminopeptidase zf-C3HC4 PF00097.25 EKX48441.1 - 0.11 12.3 8.3 0.59 10.1 8.3 2.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 EKX48441.1 - 1.5 9.2 11.3 3.7 7.9 7.0 2.7 2 0 0 2 2 2 0 RING-like domain adh_short PF00106.25 EKX48442.1 - 2.4e-24 85.9 0.0 3.1e-24 85.5 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EKX48442.1 - 2.5e-20 73.0 0.0 3.3e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX48442.1 - 1.7e-05 24.8 0.1 0.0039 17.1 0.0 2.1 2 0 0 2 2 2 2 KR domain NmrA PF05368.13 EKX48442.1 - 0.038 13.5 0.1 0.27 10.7 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family Flg_hook PF02120.16 EKX48442.1 - 0.094 12.6 0.1 1.4 8.9 0.0 2.5 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK NAD_binding_10 PF13460.6 EKX48442.1 - 0.16 11.8 0.1 0.43 10.5 0.0 1.6 2 0 0 2 2 2 0 NAD(P)H-binding ACBP PF00887.19 EKX48443.1 - 3.3e-25 88.1 0.4 3.6e-25 88.0 0.4 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein PseudoU_synth_2 PF00849.22 EKX48445.1 - 2.9e-12 46.9 0.0 5.6e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase PC-Esterase PF13839.6 EKX48447.1 - 0.029 14.1 0.1 0.097 12.4 0.0 1.7 2 0 0 2 2 2 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p AAA_21 PF13304.6 EKX48448.1 - 0.11 12.3 6.9 0.16 11.8 6.1 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SurA_N_3 PF13624.6 EKX48449.1 - 6 6.6 11.5 0.28 11.0 2.1 3.3 3 1 0 3 3 3 0 SurA N-terminal domain MDMPI_N PF11716.8 EKX48450.1 - 0.023 15.4 0.8 0.023 15.4 0.8 2.1 2 1 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain DnaJ PF00226.31 EKX48451.1 - 6.4e-16 58.2 0.3 1.2e-15 57.3 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain Hydrolase_4 PF12146.8 EKX48452.1 - 0.00045 19.6 0.0 0.001 18.4 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EKX48452.1 - 0.015 14.9 0.3 0.69 9.5 0.3 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold Lipid_DES PF08557.10 EKX48452.1 - 0.31 10.6 3.7 4 7.0 1.3 2.5 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) TPR_17 PF13431.6 EKX48454.1 - 3.5e-10 39.5 0.0 0.075 13.5 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX48454.1 - 5.9e-06 25.9 0.0 0.097 12.4 0.1 3.8 4 0 0 4 4 4 2 TPR repeat TPR_14 PF13428.6 EKX48454.1 - 7.5e-05 23.2 3.1 0.057 14.3 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX48454.1 - 0.0004 20.8 0.5 0.34 11.4 0.3 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX48454.1 - 0.0035 17.3 5.4 1.2 9.5 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX48454.1 - 0.0076 16.0 0.0 0.63 10.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX48454.1 - 0.013 15.6 1.3 2.3 8.6 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Ferritin-like PF12902.7 EKX48454.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Ferritin-like BPD_transp_1 PF00528.22 EKX48455.1 - 8.3 6.1 11.1 1.3 8.8 6.7 1.8 2 0 0 2 2 2 0 Binding-protein-dependent transport system inner membrane component eIF3g PF12353.8 EKX48455.1 - 9 6.7 7.3 15 6.0 0.1 2.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Kelch_1 PF01344.25 EKX48456.1 - 4e-64 212.0 0.1 1.5e-13 50.1 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 EKX48456.1 - 4.8e-37 125.1 0.0 3.6e-08 33.4 0.0 6.0 3 1 3 6 6 6 5 Kelch motif BACK PF07707.15 EKX48456.1 - 2.4e-24 85.4 0.1 5.4e-24 84.3 0.1 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 EKX48456.1 - 2.5e-23 81.1 0.2 1e-05 25.3 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 EKX48456.1 - 9.1e-19 67.3 0.4 0.00023 21.4 0.0 5.0 6 0 0 6 6 6 4 Galactose oxidase, central domain BTB PF00651.31 EKX48456.1 - 1.1e-15 57.8 0.0 3.6e-15 56.1 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Kelch_4 PF13418.6 EKX48456.1 - 6.1e-15 55.0 0.0 0.00034 20.6 0.0 5.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EKX48456.1 - 5.4e-09 35.8 0.2 0.05 13.6 0.0 4.4 4 0 0 4 4 4 3 Kelch motif PQQ_3 PF13570.6 EKX48456.1 - 0.0094 16.4 3.6 14 6.3 0.0 3.9 4 0 0 4 4 4 1 PQQ-like domain 2OG-Fe_Oxy_2 PF10014.9 EKX48457.1 - 0.033 14.0 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe dioxygenase Ank_4 PF13637.6 EKX48461.1 - 3.2e-23 81.8 0.1 2.2e-12 47.2 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX48461.1 - 6.1e-16 58.3 0.3 1.7e-06 28.1 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX48461.1 - 1.7e-14 53.5 0.0 0.0012 19.2 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EKX48461.1 - 2.2e-14 53.8 0.0 4.5e-13 49.6 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX48461.1 - 3.2e-13 48.5 0.0 0.00035 20.8 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Prok-RING_1 PF14446.6 EKX48461.1 - 0.05 13.5 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Myb_DNA-binding PF00249.31 EKX48462.1 - 3.5e-08 33.5 0.0 1.2e-07 31.8 0.0 1.8 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EKX48463.1 - 3.5e-08 33.5 0.0 1.2e-07 31.8 0.0 1.8 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EKX48464.1 - 3.5e-08 33.5 0.0 1.2e-07 31.8 0.0 1.8 1 1 0 1 1 1 1 Myb-like DNA-binding domain Palm_thioest PF02089.15 EKX48465.1 - 0.0033 17.3 0.0 0.0042 16.9 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase ATPase PF06745.13 EKX48466.1 - 0.019 14.3 1.1 0.04 13.2 0.0 2.1 2 0 0 2 2 2 0 KaiC RHSP PF07999.11 EKX48466.1 - 0.033 13.0 0.0 0.072 11.9 0.0 1.6 1 1 0 1 1 1 0 Retrotransposon hot spot protein DUF3552 PF12072.8 EKX48466.1 - 0.033 13.6 16.4 0.095 12.1 16.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) RNA_helicase PF00910.22 EKX48466.1 - 0.072 13.5 0.0 0.25 11.8 0.0 1.9 1 0 0 1 1 1 0 RNA helicase DUF4407 PF14362.6 EKX48466.1 - 0.65 9.3 5.9 1.3 8.3 5.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CCDC-167 PF15188.6 EKX48466.1 - 1.6 9.2 15.0 0.53 10.7 10.9 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Exonuc_VII_L PF02601.15 EKX48466.1 - 5.1 6.6 6.9 3.2 7.2 4.6 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Amidohydro_3 PF07969.11 EKX48468.1 - 1.4e-13 51.2 0.4 1.9e-06 27.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 EKX48468.1 - 1.7e-10 40.7 0.1 1.1e-06 28.3 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family CCB1 PF12046.8 EKX48469.1 - 4.4e-39 133.5 0.0 6.1e-39 133.0 0.0 1.2 1 0 0 1 1 1 1 Cofactor assembly of complex C subunit B DUF3944 PF13099.6 EKX48469.1 - 0.05 13.5 0.0 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) DUF829 PF05705.14 EKX48471.1 - 9.4e-35 120.6 0.0 1.4e-34 120.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DLH PF01738.18 EKX48471.1 - 0.016 14.8 0.0 0.079 12.5 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family Neurochondrin PF05536.11 EKX48474.1 - 4e-07 28.8 0.7 0.59 8.4 0.0 5.9 5 2 0 6 6 6 2 Neurochondrin Alkyl_sulf_dimr PF14863.6 EKX48474.1 - 1.7e-06 28.5 16.4 1.5 9.2 0.0 9.0 8 3 1 9 9 9 3 Alkyl sulfatase dimerisation Atx10homo_assoc PF09759.9 EKX48474.1 - 1.4e-05 25.0 0.0 5.2 7.1 0.2 6.8 8 0 0 8 8 8 1 Spinocerebellar ataxia type 10 protein domain Myb_DNA-binding PF00249.31 EKX48474.1 - 3.8e-05 23.8 0.0 3.8e-05 23.8 0.0 2.6 2 1 0 2 2 1 1 Myb-like DNA-binding domain Arm PF00514.23 EKX48474.1 - 0.0001 22.2 0.0 0.87 9.7 0.0 6.8 8 0 0 8 8 7 1 Armadillo/beta-catenin-like repeat WAPL PF07814.13 EKX48474.1 - 0.00097 18.0 0.4 3.7 6.2 0.0 4.2 4 1 0 4 4 4 2 Wings apart-like protein regulation of heterochromatin RICTOR_N PF14664.6 EKX48474.1 - 0.0011 18.0 0.2 15 4.5 0.0 4.6 3 2 3 6 6 6 1 Rapamycin-insensitive companion of mTOR, N-term DUF1906 PF08924.11 EKX48474.1 - 0.036 14.2 1.0 0.18 12.0 0.0 2.5 2 1 2 4 4 4 0 Domain of unknown function (DUF1906) V-ATPase_H_N PF03224.14 EKX48474.1 - 0.11 11.7 0.0 68 2.6 0.0 4.7 3 3 2 5 5 5 0 V-ATPase subunit H RTP1_C1 PF10363.9 EKX48474.1 - 0.22 11.7 1.4 77 3.5 0.0 4.7 5 1 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 DDE_Tnp_1_6 PF13751.6 EKX48474.1 - 0.54 10.5 4.0 23 5.2 0.1 3.1 3 0 0 3 3 3 0 Transposase DDE domain Tox-GHH PF15636.6 EKX48474.1 - 1.5 8.8 7.9 2.6 8.1 0.0 4.5 5 0 0 5 5 5 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin AAA PF00004.29 EKX48475.1 - 0.0048 17.3 0.2 0.015 15.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EKX48475.1 - 0.0048 16.9 0.8 0.012 15.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EKX48475.1 - 0.0049 16.5 0.3 0.011 15.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain GvpD PF07088.11 EKX48475.1 - 0.0071 15.0 0.0 0.011 14.4 0.0 1.3 1 0 0 1 1 1 1 GvpD gas vesicle protein AAA_19 PF13245.6 EKX48475.1 - 0.023 15.0 0.0 0.054 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.9 EKX48475.1 - 0.036 13.2 15.8 0.8 8.7 16.2 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_11 PF13086.6 EKX48475.1 - 0.037 13.8 12.8 0.57 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF3450 PF11932.8 EKX48475.1 - 0.044 13.1 13.4 0.083 12.2 13.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) V_ATPase_I PF01496.19 EKX48475.1 - 0.046 11.7 5.0 0.056 11.4 5.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family KASH_CCD PF14662.6 EKX48475.1 - 0.06 13.2 28.2 0.029 14.2 24.2 2.0 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH AAA_7 PF12775.7 EKX48475.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Sec34 PF04136.15 EKX48475.1 - 0.084 12.7 7.4 0.18 11.7 7.4 1.6 1 0 0 1 1 1 0 Sec34-like family Spc7 PF08317.11 EKX48475.1 - 0.096 11.6 21.8 0.015 14.2 18.0 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein RNA_helicase PF00910.22 EKX48475.1 - 0.11 13.0 0.1 0.21 12.0 0.1 1.5 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 EKX48475.1 - 0.15 11.4 6.8 0.39 10.0 0.0 2.7 3 0 0 3 3 3 0 KaiC AAA_5 PF07728.14 EKX48475.1 - 0.19 11.7 1.6 0.35 10.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EKX48475.1 - 0.22 11.8 0.1 0.22 11.8 0.1 2.6 2 2 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EKX48475.1 - 0.38 11.1 0.0 0.38 11.1 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain ERM PF00769.19 EKX48475.1 - 0.38 10.5 28.1 0.054 13.3 23.4 1.8 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF853 PF05872.12 EKX48475.1 - 0.46 9.0 0.0 0.46 9.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) DUF1664 PF07889.12 EKX48475.1 - 0.92 9.6 7.0 2 8.5 6.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) ABC_tran PF00005.27 EKX48475.1 - 1.6 9.3 4.2 19 5.7 0.0 2.3 2 0 0 2 2 2 0 ABC transporter TMPIT PF07851.13 EKX48475.1 - 2.3 7.4 11.6 4.9 6.3 11.6 1.5 1 0 0 1 1 1 0 TMPIT-like protein UPF0242 PF06785.11 EKX48475.1 - 4.9 7.2 20.3 6.4 6.8 18.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Fmp27_WPPW PF10359.9 EKX48475.1 - 6 5.6 16.0 10 4.9 16.0 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain PAP_assoc PF03828.19 EKX48476.1 - 0.0042 17.3 0.1 0.018 15.2 0.0 2.2 2 1 0 2 2 2 1 Cid1 family poly A polymerase tRNA_NucTransf2 PF09249.11 EKX48476.1 - 0.077 13.3 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 tRNA nucleotidyltransferase, second domain PAP_central PF04928.17 EKX48476.1 - 0.27 10.2 2.4 9.4 5.1 2.5 2.6 2 1 0 2 2 2 0 Poly(A) polymerase central domain PPR_2 PF13041.6 EKX48477.1 - 0.045 13.9 0.8 0.99 9.6 0.0 3.2 2 1 1 3 3 3 0 PPR repeat family Polysacc_synt_4 PF04669.13 EKX48478.1 - 5.7e-28 97.8 0.0 1.8e-27 96.2 0.0 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis Methyltransf_24 PF13578.6 EKX48478.1 - 0.047 14.7 0.0 0.23 12.5 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain E1_dh PF00676.20 EKX48479.1 - 5.6e-51 173.3 0.0 7.9e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 EKX48479.1 - 1.6e-48 164.8 0.0 7.1e-48 162.6 0.0 1.9 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 EKX48479.1 - 1.7e-37 128.5 0.0 3.2e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal Tim44 PF04280.15 EKX48480.1 - 2.9e-06 27.5 0.3 3.8e-06 27.1 0.3 1.1 1 0 0 1 1 1 1 Tim44-like domain MSP PF01716.18 EKX48480.1 - 0.08 12.1 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Manganese-stabilising protein / photosystem II polypeptide Gp_dh_C PF02800.20 EKX48480.1 - 0.14 11.8 0.2 0.21 11.2 0.2 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Glyco_transf_49 PF13896.6 EKX48481.1 - 5.4e-22 78.6 2.3 2.4e-11 43.6 0.4 3.1 2 1 1 3 3 3 3 Glycosyl-transferase for dystroglycan HA PF03457.14 EKX48482.1 - 9.5e-91 298.1 37.8 1.1e-18 67.3 0.1 8.8 8 1 0 8 8 8 7 Helicase associated domain DUF3782 PF12644.7 EKX48482.1 - 0.031 14.4 1.4 0.78 9.9 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) DUF716 PF04819.12 EKX48482.1 - 0.1 12.2 0.4 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF716) DUF4817 PF16087.5 EKX48482.1 - 1.6 8.6 3.6 1e+02 2.8 0.0 4.1 4 0 0 4 4 4 0 Helix-turn-helix domain (DUF4817) Pkinase PF00069.25 EKX48483.1 - 4.4e-66 223.0 0.0 4.9e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX48483.1 - 3.9e-27 95.2 0.0 5.2e-27 94.8 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX48483.1 - 6.6e-09 35.5 0.0 0.001 18.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 EKX48483.1 - 0.00016 21.1 0.0 0.00023 20.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX48483.1 - 0.0013 18.7 0.1 0.016 15.1 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EKX48483.1 - 0.024 14.2 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1761 PF08570.10 EKX48484.1 - 0.12 12.6 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1761) Peptidase_M13_N PF05649.13 EKX48485.1 - 1.4e-65 222.5 0.0 1.7e-65 222.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 EKX48485.1 - 4.5e-52 176.6 0.2 7.8e-52 175.9 0.2 1.4 1 0 0 1 1 1 1 Peptidase family M13 PDEase_I PF00233.19 EKX48488.1 - 3.7e-58 197.1 2.2 4.8e-58 196.7 2.2 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HhH-GPD PF00730.25 EKX48489.1 - 5.8e-16 58.9 0.0 8.1e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EKX48489.1 - 4.8e-08 32.5 1.1 1e-07 31.4 0.1 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EKX48489.1 - 0.00086 19.9 0.0 0.15 12.7 0.1 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.7 EKX48489.1 - 0.0024 17.9 0.0 1.2 9.3 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_8 PF14716.6 EKX48489.1 - 0.018 15.4 0.2 0.037 14.4 0.2 1.7 1 1 0 1 1 1 0 Helix-hairpin-helix domain PG_binding_2 PF08823.11 EKX48489.1 - 0.11 12.9 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative peptidoglycan binding domain HHH_3 PF12836.7 EKX48489.1 - 0.18 12.1 0.0 0.42 10.9 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif IBR PF01485.21 EKX48490.1 - 7.5e-13 48.5 2.5 7.5e-13 48.5 2.5 4.3 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 EKX48490.1 - 6.3e-07 29.3 9.2 1.1e-05 25.4 1.3 2.8 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4 PF00097.25 EKX48490.1 - 2e-05 24.4 2.9 2e-05 24.4 2.9 3.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX48490.1 - 9.8e-05 22.6 3.6 9.8e-05 22.6 3.6 4.2 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX48490.1 - 0.00013 21.7 1.9 0.00013 21.7 1.9 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX48490.1 - 0.00041 20.2 3.5 0.00041 20.2 3.5 3.5 2 2 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 EKX48490.1 - 0.023 14.4 2.4 0.023 14.4 2.4 3.2 3 0 0 3 3 3 0 RING-like zinc finger UBA_4 PF14555.6 EKX48490.1 - 0.041 13.7 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain zf-C3HC4_3 PF13920.6 EKX48490.1 - 0.58 10.1 18.6 0.091 12.6 2.9 4.0 2 2 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EKX48490.1 - 2.3 8.5 19.7 1.6 9.0 0.7 3.9 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING TIR_2 PF13676.6 EKX48491.1 - 0.00015 22.4 0.0 0.00031 21.3 0.0 1.5 1 0 0 1 1 1 1 TIR domain Ank PF00023.30 EKX48492.1 - 1.6e-11 44.1 0.2 5.7e-05 23.4 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 EKX48492.1 - 2.5e-09 37.6 0.0 7.8e-09 36.0 0.0 1.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX48492.1 - 5.7e-09 36.3 0.0 4.7e-07 30.2 0.0 2.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX48492.1 - 1.4e-07 31.3 0.6 0.00099 19.4 0.0 3.8 3 1 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EKX48492.1 - 1.4e-06 28.4 0.1 1.4e-05 25.3 0.1 2.4 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Rhomboid PF01694.22 EKX48492.1 - 0.045 13.8 0.0 0.057 13.4 0.0 1.1 1 0 0 1 1 1 0 Rhomboid family Fer2_4 PF13510.6 EKX48492.1 - 0.048 13.7 0.2 0.66 10.1 0.0 2.2 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain DDE_Tnp_1_7 PF13843.6 EKX48493.1 - 9.8e-24 84.3 0.0 2.1e-23 83.2 0.0 1.5 1 1 0 1 1 1 1 Transposase IS4 DUF3236 PF11576.8 EKX48493.1 - 0.063 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) Laminin_B PF00052.18 EKX48494.1 - 3.6e-13 49.6 0.1 2.1e-12 47.1 0.0 2.2 2 1 0 2 2 2 1 Laminin B (Domain IV) Nucleotid_trans PF03407.16 EKX48495.1 - 5.7e-23 82.0 0.0 8.4e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase CG-1 PF03859.16 EKX48496.1 - 2.8e-34 117.4 1.3 9.3e-34 115.7 1.3 1.8 1 1 0 1 1 1 1 CG-1 domain DUF2605 PF10792.9 EKX48496.1 - 5.2 7.1 8.9 0.26 11.3 1.1 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2605) THOC2_N PF16134.5 EKX48497.1 - 1 7.9 15.8 0.32 9.6 1.0 2.5 2 1 1 3 3 3 0 THO complex subunit 2 N-terminus CENP-B_dimeris PF09026.10 EKX48497.1 - 6.2 7.3 13.3 17 5.9 5.4 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Pkinase PF00069.25 EKX48498.1 - 2.8e-63 213.8 0.0 3.9e-63 213.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX48498.1 - 6.2e-30 104.3 0.0 8.4e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX48498.1 - 5.8e-09 35.7 0.0 1.5e-07 31.0 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EKX48498.1 - 0.0004 19.3 0.0 0.00083 18.2 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EKX48498.1 - 0.091 12.7 0.0 0.18 11.7 0.0 1.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family POM121 PF15229.6 EKX48499.1 - 0.024 14.3 0.2 0.024 14.3 0.2 2.4 1 1 0 2 2 2 0 POM121 family PDZ_6 PF17820.1 EKX48500.1 - 1.8e-08 34.1 0.1 5.3e-08 32.6 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX48500.1 - 2.6e-07 30.9 2.7 2.8e-07 30.8 0.6 2.2 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX48500.1 - 0.00023 21.4 0.1 0.00076 19.8 0.1 1.8 1 0 0 1 1 1 1 PDZ domain DHC_N1 PF08385.12 EKX48502.1 - 2.1e-78 264.4 26.1 4.7e-61 207.1 11.7 3.6 3 0 0 3 3 3 2 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 EKX48502.1 - 5e-40 137.8 15.1 5e-40 137.8 15.1 4.5 7 0 0 7 7 7 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 EKX48502.1 - 2.6e-26 92.4 0.0 1.9e-25 89.5 0.0 2.4 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 EKX48502.1 - 3.3e-24 85.4 1.1 2.1e-22 79.5 0.2 3.3 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_8 PF12780.7 EKX48502.1 - 5.6e-20 71.7 1.4 4.7e-15 55.6 0.1 3.1 2 1 0 2 2 2 2 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EKX48502.1 - 4.1e-19 68.6 3.1 1.7e-17 63.3 0.0 3.8 3 0 0 3 3 3 1 ATP-binding dynein motor region Dynein_C PF18199.1 EKX48502.1 - 1.5e-17 63.8 0.2 7.2e-17 61.6 0.2 2.2 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain MT PF12777.7 EKX48502.1 - 9.4e-16 57.8 8.6 1.8e-15 56.8 8.6 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 EKX48502.1 - 1e-12 48.2 0.0 0.0001 22.3 0.0 5.0 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EKX48502.1 - 3.4e-12 47.1 0.3 0.038 14.4 0.0 4.8 3 0 0 3 3 3 3 AAA ATPase domain Dynein_AAA_lid PF17852.1 EKX48502.1 - 1.3e-07 31.8 1.0 1.2e-06 28.7 0.2 3.1 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 EKX48502.1 - 3.5e-05 24.1 0.0 12 6.2 0.0 4.3 3 0 0 3 3 3 0 AAA domain UPF0242 PF06785.11 EKX48502.1 - 0.0015 18.7 5.3 0.0015 18.7 5.3 4.3 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus DUF815 PF05673.13 EKX48502.1 - 0.002 17.3 0.2 0.91 8.6 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF815) PIF1 PF05970.14 EKX48502.1 - 0.004 16.4 0.0 0.016 14.4 0.0 2.0 1 0 0 1 1 1 1 PIF1-like helicase CobT PF06213.12 EKX48502.1 - 0.0068 15.8 3.4 0.016 14.6 3.4 1.5 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT AAA_lid_1 PF17857.1 EKX48502.1 - 0.011 16.0 3.1 0.2 11.9 0.0 4.0 4 0 0 4 4 3 0 AAA+ lid domain ABC_tran PF00005.27 EKX48502.1 - 0.012 16.1 2.9 29 5.2 0.0 4.3 4 0 0 4 4 3 0 ABC transporter RsgA_GTPase PF03193.16 EKX48502.1 - 0.019 14.8 0.1 0.4 10.6 0.0 3.1 3 0 0 3 3 3 0 RsgA GTPase RNA_helicase PF00910.22 EKX48502.1 - 0.021 15.2 0.1 18 5.8 0.0 4.4 3 0 0 3 3 3 0 RNA helicase FtsK_SpoIIIE PF01580.18 EKX48502.1 - 0.029 13.7 0.1 1.1 8.5 0.1 2.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family Sigma54_activat PF00158.26 EKX48502.1 - 0.051 13.3 0.1 6.9 6.3 0.0 3.4 3 0 0 3 3 3 0 Sigma-54 interaction domain Roc PF08477.13 EKX48502.1 - 0.072 13.3 1.4 3.5 7.9 0.0 3.3 3 1 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 EKX48502.1 - 0.073 12.8 0.0 1 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain FAM176 PF14851.6 EKX48502.1 - 0.55 9.9 4.3 1.9 8.1 4.3 2.0 1 0 0 1 1 1 0 FAM176 family Hydin_ADK PF17213.3 EKX48502.1 - 1.7 8.9 3.8 6.6 7.0 3.8 2.0 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain JHD PF17811.1 EKX48502.1 - 3.4 8.3 6.1 4.2 7.9 0.5 3.6 3 0 0 3 3 2 0 Jumonji helical domain AAA_18 PF13238.6 EKX48502.1 - 7 7.2 5.7 26 5.4 0.0 4.6 4 0 0 4 4 3 0 AAA domain ABC_tran PF00005.27 EKX48503.1 - 8.1e-19 68.5 0.0 1.3e-18 67.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EKX48503.1 - 0.0021 18.4 0.0 0.0042 17.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.6 EKX48503.1 - 0.037 13.7 0.0 0.044 13.5 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EKX48503.1 - 0.1 12.8 0.0 1.5 9.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EKX48503.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 EKX48503.1 - 0.12 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 EKX48503.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family TPR_12 PF13424.6 EKX48504.1 - 6.5e-60 199.4 20.6 2e-14 53.6 1.0 8.1 5 2 3 8 8 8 7 Tetratricopeptide repeat CHAT PF12770.7 EKX48504.1 - 5.6e-54 183.5 0.2 1.1e-53 182.6 0.2 1.4 1 0 0 1 1 1 1 CHAT domain TPR_7 PF13176.6 EKX48504.1 - 2.6e-43 142.9 8.5 2.9e-05 23.8 0.2 10.5 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_1 PF00515.28 EKX48504.1 - 3.7e-41 137.3 19.8 7.8e-06 25.5 0.8 10.0 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_10 PF13374.6 EKX48504.1 - 1e-38 130.1 13.6 0.00014 21.6 0.0 10.1 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 EKX48504.1 - 1e-26 90.8 21.5 0.00063 19.8 0.0 11.4 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_2 PF07719.17 EKX48504.1 - 4.7e-22 76.3 23.1 8.9e-05 22.3 0.3 10.2 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 EKX48504.1 - 8.5e-13 48.0 2.8 0.19 12.6 0.0 8.9 6 1 3 9 9 8 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX48504.1 - 1.6e-10 40.9 3.8 0.00074 19.0 0.1 4.2 1 1 2 4 4 4 4 MalT-like TPR region TPR_16 PF13432.6 EKX48504.1 - 1.7e-07 31.7 3.1 2.6 8.8 0.3 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat RPN7 PF10602.9 EKX48504.1 - 3.5e-06 26.8 7.3 0.044 13.5 0.1 5.2 4 1 1 5 5 5 2 26S proteasome subunit RPN7 SNAP PF14938.6 EKX48504.1 - 6.4e-05 22.5 5.9 0.00011 21.7 0.2 3.0 1 1 2 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_17 PF13431.6 EKX48504.1 - 7.3e-05 22.9 17.0 6.3 7.4 0.0 7.3 8 0 0 8 8 6 2 Tetratricopeptide repeat Rapsyn_N PF10579.9 EKX48504.1 - 0.00012 22.1 1.3 13 5.9 0.0 5.8 5 1 0 5 5 5 0 Rapsyn N-terminal myristoylation and linker region PPR PF01535.20 EKX48504.1 - 0.00046 20.3 5.6 1.6 9.1 0.0 6.0 5 0 0 5 5 5 1 PPR repeat TPR_4 PF07721.14 EKX48504.1 - 0.00056 20.3 6.8 10 7.1 0.0 7.5 9 0 0 9 9 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX48504.1 - 0.0011 19.4 4.6 2.3 8.8 0.0 5.3 3 2 2 5 5 5 1 Tetratricopeptide repeat DUF4810 PF16068.5 EKX48504.1 - 0.0014 19.1 7.8 1.6 9.3 0.0 5.1 6 1 0 6 6 4 2 Domain of unknown function (DUF4810) ANAPC5 PF12862.7 EKX48504.1 - 0.0048 16.9 2.4 13 6.0 0.0 4.8 5 1 0 5 5 4 0 Anaphase-promoting complex subunit 5 DUF3856 PF12968.7 EKX48504.1 - 0.007 16.4 9.7 23 5.0 0.2 5.7 3 2 2 6 6 6 0 Domain of Unknown Function (DUF3856) DUF5113 PF17140.4 EKX48504.1 - 0.017 14.9 3.3 2.7 7.8 0.2 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF5113) TPR_6 PF13174.6 EKX48504.1 - 0.018 15.6 15.7 11 6.9 0.0 8.3 11 0 0 11 11 7 0 Tetratricopeptide repeat zf-CHY PF05495.12 EKX48505.1 - 2.3e-18 66.4 17.7 2.3e-18 66.4 17.7 3.4 2 1 1 3 3 3 1 CHY zinc finger zf-C3HC4_2 PF13923.6 EKX48505.1 - 2.4e-06 27.3 7.3 2.4e-06 27.3 7.3 5.4 3 2 2 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EKX48505.1 - 0.00068 19.4 3.0 0.00068 19.4 3.0 4.5 2 2 2 4 4 4 1 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.14 EKX48505.1 - 0.0071 16.2 0.3 0.0071 16.2 0.3 3.1 3 0 0 3 3 3 1 Rad50 zinc hook motif Tfb5 PF06331.12 EKX48506.1 - 2.1e-07 30.8 0.4 2.5e-07 30.6 0.4 1.1 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Nrap_D6 PF17407.2 EKX48506.1 - 0.034 14.4 0.0 0.034 14.3 0.0 1.1 1 0 0 1 1 1 0 Nrap protein domain 6 Asp PF00026.23 EKX48507.1 - 5e-24 85.3 0.0 2.9e-16 59.8 0.0 2.8 2 1 0 3 3 3 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EKX48507.1 - 2.7e-10 40.8 0.0 0.00055 20.2 0.0 2.8 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal IFT20 PF14931.6 EKX48508.1 - 1.1e-34 119.2 12.3 1.2e-34 119.0 12.3 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 MscS_porin PF12795.7 EKX48508.1 - 0.0013 18.3 13.1 0.002 17.7 13.1 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain WXG100 PF06013.12 EKX48508.1 - 0.0086 16.3 4.9 0.22 11.8 0.1 2.2 2 0 0 2 2 2 1 Proteins of 100 residues with WXG Sec2p PF06428.11 EKX48508.1 - 0.011 15.7 7.8 0.011 15.7 7.8 2.1 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p FmiP_Thoc5 PF09766.9 EKX48508.1 - 0.013 14.8 7.6 0.016 14.6 7.6 1.2 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 DUF2968 PF11180.8 EKX48508.1 - 0.019 14.6 14.1 0.027 14.1 14.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) ING PF12998.7 EKX48508.1 - 0.049 14.2 4.9 0.077 13.6 4.9 1.3 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding FlxA PF14282.6 EKX48508.1 - 0.073 13.1 15.2 0.1 12.6 15.0 1.5 1 1 0 1 1 1 0 FlxA-like protein DUF4407 PF14362.6 EKX48508.1 - 0.11 11.9 8.9 0.12 11.6 8.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Syntaxin_2 PF14523.6 EKX48508.1 - 0.11 12.9 10.1 0.2 12.0 10.1 1.5 1 1 0 1 1 1 0 Syntaxin-like protein THOC7 PF05615.13 EKX48508.1 - 0.13 12.6 15.7 0.26 11.6 15.7 1.5 1 1 0 1 1 1 0 Tho complex subunit 7 BLOC1_2 PF10046.9 EKX48508.1 - 0.17 12.2 9.1 4.6 7.6 0.2 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3450 PF11932.8 EKX48508.1 - 0.19 11.0 14.0 0.81 8.9 12.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ISG65-75 PF11727.8 EKX48508.1 - 0.26 10.5 5.9 0.32 10.2 5.9 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Atg14 PF10186.9 EKX48508.1 - 0.28 10.2 12.7 0.36 9.9 12.7 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FAM76 PF16046.5 EKX48508.1 - 0.29 10.5 7.2 0.35 10.2 7.2 1.1 1 0 0 1 1 1 0 FAM76 protein Cluap1 PF10234.9 EKX48508.1 - 0.33 10.3 10.9 1 8.7 10.9 1.7 1 1 0 1 1 1 0 Clusterin-associated protein-1 AAA_13 PF13166.6 EKX48508.1 - 0.34 9.5 8.9 0.4 9.3 8.9 1.0 1 0 0 1 1 1 0 AAA domain DUF641 PF04859.12 EKX48508.1 - 0.37 11.1 10.8 0.44 10.9 4.6 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Exonuc_VII_L PF02601.15 EKX48508.1 - 0.38 10.3 8.6 0.42 10.1 8.6 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 EKX48508.1 - 0.49 9.2 14.8 0.6 8.9 14.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Spc24 PF08286.11 EKX48508.1 - 0.5 10.6 11.0 0.57 10.4 5.9 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF4140 PF13600.6 EKX48508.1 - 0.58 10.6 8.7 1.5 9.3 8.7 1.7 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Occludin_ELL PF07303.13 EKX48508.1 - 0.67 10.7 8.2 4.8 8.0 1.5 2.1 1 1 1 2 2 2 0 Occludin homology domain DUF1664 PF07889.12 EKX48508.1 - 0.79 9.8 6.7 1.1 9.4 6.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2203 PF09969.9 EKX48508.1 - 0.99 10.1 6.1 1.5 9.5 6.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) TMPIT PF07851.13 EKX48508.1 - 1 8.6 8.5 1.3 8.2 8.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein OmpH PF03938.14 EKX48508.1 - 1 9.7 15.8 1.5 9.1 15.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Swi5 PF07061.11 EKX48508.1 - 1 9.5 8.2 1.9 8.6 3.3 2.2 2 0 0 2 2 2 0 Swi5 UPF0242 PF06785.11 EKX48508.1 - 1.1 9.3 12.8 1.6 8.8 12.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus RmuC PF02646.16 EKX48508.1 - 1.5 7.9 12.0 1.1 8.3 0.3 2.0 1 1 1 2 2 2 0 RmuC family YabA PF06156.13 EKX48508.1 - 1.5 9.5 9.7 19 5.9 7.1 2.1 1 1 1 2 2 2 0 Initiation control protein YabA DUF4404 PF14357.6 EKX48508.1 - 2 9.1 10.1 0.36 11.5 2.0 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4404) SseC PF04888.12 EKX48508.1 - 2.3 7.7 9.7 13 5.3 9.6 1.9 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family DUF724 PF05266.14 EKX48508.1 - 2.8 7.7 13.9 1.9 8.3 10.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) AAA_23 PF13476.6 EKX48508.1 - 4.1 7.9 11.2 4.7 7.6 11.2 1.1 1 0 0 1 1 1 0 AAA domain SlyX PF04102.12 EKX48508.1 - 5.6 7.7 11.2 6.6 7.4 6.1 2.4 1 1 1 2 2 2 0 SlyX FapA PF03961.13 EKX48508.1 - 5.8 5.4 10.5 15 4.1 7.3 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A MRPL52 PF18699.1 EKX48508.1 - 8.5 6.6 14.2 0.46 10.7 0.3 2.1 1 1 1 2 2 2 0 Mitoribosomal protein mL52 PKD_channel PF08016.12 EKX48509.1 - 5.8e-33 114.2 20.3 4.4e-20 71.8 0.2 4.1 2 2 2 4 4 4 4 Polycystin cation channel Ion_trans PF00520.31 EKX48509.1 - 0.0028 16.9 22.6 0.057 12.6 7.7 3.1 3 1 0 3 3 3 2 Ion transport protein SNAPc_SNAP43 PF09808.9 EKX48509.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 NRIP1_repr_1 PF15687.5 EKX48509.1 - 0.06 13.0 1.0 0.098 12.3 1.0 1.2 1 0 0 1 1 1 0 Nuclear receptor-interacting protein 1 repression 1 Phage_tube PF04985.14 EKX48509.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Phage tail tube protein FII EF-hand_6 PF13405.6 EKX48509.1 - 0.4 10.7 1.9 0.55 10.3 0.2 2.1 2 0 0 2 2 2 0 EF-hand domain zf-CCCH PF00642.24 EKX48510.1 - 1.4e-10 40.8 2.8 1.4e-10 40.8 2.8 2.1 3 0 0 3 3 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EKX48510.1 - 5e-07 29.6 4.0 5e-07 29.6 4.0 2.2 2 0 0 2 2 2 1 Zinc finger domain zf-C3HC4_3 PF13920.6 EKX48510.1 - 5.3e-06 26.2 7.3 1e-05 25.2 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX48510.1 - 8.7e-06 25.7 7.0 2.1e-05 24.4 7.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EKX48510.1 - 1.4e-05 24.8 8.0 2.9e-05 23.8 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_4 PF18044.1 EKX48510.1 - 4.5e-05 23.1 2.4 4.5e-05 23.1 2.4 3.0 4 0 0 4 4 4 1 CCCH-type zinc finger zf-C3HC4 PF00097.25 EKX48510.1 - 6.8e-05 22.7 9.9 0.00013 21.7 9.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX48510.1 - 0.0001 22.5 8.3 0.0001 22.5 8.3 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 EKX48510.1 - 0.00011 22.1 9.9 0.00021 21.2 9.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_10 PF16685.5 EKX48510.1 - 0.0032 17.6 4.2 0.0032 17.6 4.2 1.8 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 EKX48510.1 - 0.0053 16.9 8.8 0.013 15.7 8.8 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Imm42 PF15593.6 EKX48510.1 - 0.045 14.2 0.1 0.095 13.2 0.1 1.5 1 0 0 1 1 1 0 Immunity protein 42 zf-CCCH_2 PF14608.6 EKX48510.1 - 0.065 13.7 2.0 0.065 13.7 2.0 2.0 2 0 0 2 2 1 0 RNA-binding, Nab2-type zinc finger Prok-RING_4 PF14447.6 EKX48510.1 - 0.098 12.5 6.2 0.19 11.6 6.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 EKX48510.1 - 1.4 8.8 6.9 1.1 9.1 3.7 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.14 EKX48510.1 - 3.1 7.5 7.5 8.7 6.1 7.5 1.7 1 1 0 1 1 1 0 P-11 zinc finger HlyIII PF03006.20 EKX48512.1 - 3.2e-24 85.9 17.4 4.5e-24 85.4 17.4 1.2 1 0 0 1 1 1 1 Haemolysin-III related Thioredoxin PF00085.20 EKX48513.1 - 0.0022 18.0 0.0 0.0033 17.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Proteasome PF00227.26 EKX48514.1 - 2.5e-61 206.5 0.4 3.2e-61 206.1 0.4 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EKX48514.1 - 3e-14 52.4 0.1 6.8e-14 51.2 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Hint PF01079.20 EKX48515.1 - 8.6e-24 84.2 0.0 1.2e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Hint module Vint PF14623.6 EKX48515.1 - 0.0068 16.2 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Hint-domain Hint_2 PF13403.6 EKX48515.1 - 0.022 15.0 0.0 0.18 12.1 0.0 2.1 1 1 0 2 2 2 0 Hint domain PT-HINT PF07591.11 EKX48515.1 - 0.024 14.9 0.0 0.053 13.8 0.0 1.5 1 1 0 1 1 1 0 Pretoxin HINT domain DUF1373 PF07117.11 EKX48515.1 - 7.9 6.4 11.1 0.39 10.7 5.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1373) Hint PF01079.20 EKX48516.1 - 5.9e-22 78.2 1.9 1e-21 77.4 1.9 1.3 1 0 0 1 1 1 1 Hint module Hom_end_hint PF05203.16 EKX48516.1 - 0.0032 17.5 1.5 0.09 12.7 0.1 3.0 3 0 0 3 3 3 1 Hom_end-associated Hint Peptidase_M17 PF00883.21 EKX48518.1 - 6.5e-99 331.1 3.4 5.7e-97 324.8 3.4 2.3 1 1 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 EKX48518.1 - 1.1e-17 64.0 3.2 1.1e-17 64.0 3.2 1.9 2 0 0 2 2 2 1 Cytosol aminopeptidase family, N-terminal domain RWP-RK PF02042.15 EKX48519.1 - 1.8e-13 50.2 0.0 2.8e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX48519.1 - 0.039 13.8 0.2 0.12 12.2 0.1 1.8 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family HTH_28 PF13518.6 EKX48519.1 - 0.042 14.0 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 EKX48519.1 - 0.069 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 RWP-RK PF02042.15 EKX48520.1 - 2.9e-13 49.5 0.1 5.5e-13 48.7 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain FAM199X PF15814.5 EKX48520.1 - 1.7 7.6 9.5 2.4 7.1 9.5 1.2 1 0 0 1 1 1 0 Protein family FAM199X DUF5585 PF17823.1 EKX48520.1 - 4.7 6.1 20.7 6.1 5.7 20.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Rgp1 PF08737.10 EKX48521.1 - 1.2e-23 84.0 0.6 1.8e-12 47.2 0.0 2.1 1 1 0 2 2 2 2 Rgp1 Arrestin_C PF02752.22 EKX48521.1 - 2.7e-05 24.6 0.0 0.075 13.5 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EKX48521.1 - 0.039 14.0 0.1 0.17 11.9 0.1 2.0 3 0 0 3 3 3 0 Arrestin (or S-antigen), N-terminal domain zf-C3HC4 PF00097.25 EKX48522.1 - 0.00025 20.9 6.9 0.00025 20.9 6.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX48522.1 - 0.001 19.4 8.2 0.0013 19.0 6.6 2.0 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 EKX48522.1 - 0.0019 18.1 10.5 0.011 15.6 10.5 2.2 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EKX48522.1 - 0.002 17.9 11.0 0.011 15.5 9.7 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EKX48522.1 - 0.0081 16.0 3.9 0.018 14.9 3.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX48522.1 - 0.015 15.1 4.9 0.015 15.1 4.9 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EKX48522.1 - 0.035 13.7 8.9 0.45 10.2 9.1 2.2 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type FYDLN_acid PF09538.10 EKX48522.1 - 0.038 14.7 0.3 0.071 13.8 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-Di19 PF05605.12 EKX48522.1 - 0.05 13.9 11.9 3 8.2 8.2 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.7 EKX48522.1 - 0.07 13.2 9.1 0.4 10.7 5.4 2.6 2 1 1 3 3 3 0 Double zinc ribbon DUF2225 PF09986.9 EKX48522.1 - 0.082 12.6 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-RING_UBOX PF13445.6 EKX48522.1 - 0.14 12.2 4.6 0.16 12.1 3.0 2.0 1 1 0 1 1 1 0 RING-type zinc-finger Prok-RING_2 PF14445.6 EKX48522.1 - 0.4 10.9 4.9 2 8.7 4.9 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 2 Prok-RING_1 PF14446.6 EKX48522.1 - 0.71 9.8 10.6 1.3 9.0 4.9 2.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.6 EKX48522.1 - 1.4 9.2 5.7 0.68 10.1 1.7 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING PHD PF00628.29 EKX48522.1 - 3.2 7.7 10.3 5.7 6.9 8.7 2.2 2 1 0 2 2 2 0 PHD-finger HEAT_EZ PF13513.6 EKX48523.1 - 0.025 15.1 0.7 12 6.5 0.1 2.5 2 0 0 2 2 2 0 HEAT-like repeat Pkinase PF00069.25 EKX48524.1 - 1.4e-12 47.6 0.1 1.5e-12 47.4 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX48524.1 - 0.0018 17.6 0.0 0.0019 17.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX48525.1 - 2.9e-51 174.4 0.0 3.4e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX48525.1 - 3.7e-23 82.1 0.0 4.6e-23 81.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX48525.1 - 2.6e-07 30.3 0.0 1.7e-06 27.6 0.0 1.9 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EKX48525.1 - 0.00069 18.7 0.0 0.0033 16.4 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 EKX48525.1 - 0.0091 15.1 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 EKX48525.1 - 0.017 15.0 0.1 0.022 14.7 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribonuc_red_lgC PF02867.15 EKX48525.1 - 0.063 11.8 0.1 0.16 10.5 0.1 1.6 1 1 1 2 2 2 0 Ribonucleotide reductase, barrel domain Kdo PF06293.14 EKX48525.1 - 0.08 12.3 0.1 0.19 11.1 0.1 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sushi PF00084.20 EKX48526.1 - 1.1e-34 118.7 93.3 1.3e-06 28.9 1.2 20.3 20 1 1 21 21 21 14 Sushi repeat (SCR repeat) ZU5 PF00791.20 EKX48526.1 - 0.00043 20.6 0.0 0.0015 18.9 0.0 2.0 1 0 0 1 1 1 1 ZU5 domain SHR3_chaperone PF08229.11 EKX48526.1 - 0.036 13.1 0.0 0.079 11.9 0.0 1.5 1 0 0 1 1 1 0 ER membrane protein SH3 Mitofilin PF09731.9 EKX48526.1 - 0.12 11.2 16.6 0.17 10.7 16.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Saf_2TM PF18303.1 EKX48526.1 - 0.25 10.9 0.0 0.45 10.1 0.0 1.3 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain DBINO PF13892.6 EKX48527.1 - 0.62 10.4 14.9 0.37 11.1 8.0 2.2 2 0 0 2 2 2 0 DNA-binding domain PAS_10 PF13596.6 EKX48527.1 - 0.88 10.2 3.3 13 6.5 0.0 2.9 2 1 1 3 3 3 0 PAS domain CdiA_C PF18451.1 EKX48527.1 - 2.7 8.3 11.7 0.22 11.8 3.6 2.9 2 1 1 3 3 3 0 Contact-dependent growth inhibition CdiA C-terminal domain Pkinase PF00069.25 EKX48531.1 - 3.9e-49 167.4 0.0 5e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX48531.1 - 8e-28 97.4 0.0 1.1e-27 97.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX48531.1 - 0.0058 15.4 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX48531.1 - 0.045 13.7 0.0 0.12 12.3 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EKX48531.1 - 0.058 12.7 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 EKX48531.1 - 0.14 11.7 0.0 0.85 9.2 0.0 2.0 1 1 1 2 2 2 0 Choline/ethanolamine kinase Rotamase PF00639.21 EKX48533.1 - 1.3e-09 38.8 0.0 2.4e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EKX48533.1 - 4.5e-08 33.7 0.1 6.5e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain IQ PF00612.27 EKX48535.1 - 4.3e-05 22.9 15.6 0.1 12.4 0.5 4.1 3 0 0 3 3 3 3 IQ calmodulin-binding motif WW PF00397.26 EKX48535.1 - 0.027 14.6 0.9 0.064 13.3 0.9 1.7 1 0 0 1 1 1 0 WW domain Anoctamin PF04547.12 EKX48536.1 - 1.1e-21 77.2 11.1 5e-16 58.6 0.9 2.2 2 0 0 2 2 2 2 Calcium-activated chloride channel Anoct_dimer PF16178.5 EKX48536.1 - 0.029 14.1 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin WD40 PF00400.32 EKX48537.1 - 1.4e-17 63.8 12.9 8.6e-06 26.4 0.3 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat BTB PF00651.31 EKX48537.1 - 0.0001 22.5 0.0 0.00018 21.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain GST_C_3 PF14497.6 EKX48538.1 - 1.3e-16 60.5 0.0 1.8e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EKX48538.1 - 6.9e-06 26.2 0.0 1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EKX48538.1 - 0.00034 20.6 0.0 0.00065 19.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EKX48538.1 - 0.019 15.3 0.0 0.033 14.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain RWP-RK PF02042.15 EKX48540.1 - 9e-15 54.4 0.0 1.3e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX48541.1 - 3.9e-14 52.4 0.0 6.2e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain Sigma70_r4_2 PF08281.12 EKX48541.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_17 PF12728.7 EKX48541.1 - 0.13 12.5 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain RWP-RK PF02042.15 EKX48542.1 - 4.9e-16 58.4 0.0 7.4e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain DUF134 PF02001.16 EKX48542.1 - 0.1 13.2 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF134 UPF0029 PF01205.19 EKX48543.1 - 3e-29 101.4 0.0 5.4e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DUF1949 PF09186.11 EKX48543.1 - 2e-10 40.4 0.1 3.4e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1949) TPR_2 PF07719.17 EKX48544.1 - 3.2e-05 23.7 1.5 4.7 7.6 0.0 5.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX48544.1 - 0.003 17.3 2.1 5.1 7.1 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX48544.1 - 0.0052 17.5 5.8 0.035 14.9 0.1 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX48544.1 - 0.018 15.2 0.4 6.7 7.2 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX48544.1 - 0.037 14.2 10.6 0.42 10.9 0.1 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EKX48544.1 - 0.041 14.2 7.4 0.3 11.4 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat NOA36 PF06524.12 EKX48544.1 - 1.6 8.0 11.1 3 7.1 11.1 1.4 1 0 0 1 1 1 0 NOA36 protein BUD22 PF09073.10 EKX48544.1 - 7.5 5.8 16.9 13 4.9 16.9 1.3 1 0 0 1 1 1 0 BUD22 DSPc PF00782.20 EKX48545.1 - 2e-06 27.6 0.0 2.8e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EKX48545.1 - 5.9e-06 26.4 0.0 6.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EKX48545.1 - 1.9e-05 24.8 0.0 2.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 EKX48545.1 - 2.8e-05 23.8 0.0 3.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 EKX48545.1 - 0.0018 18.0 0.0 0.0029 17.3 0.0 1.4 1 1 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase2 PF03162.13 EKX48545.1 - 0.17 11.5 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 EKX48546.1 - 2e-06 27.6 0.0 2.8e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EKX48546.1 - 5.9e-06 26.4 0.0 6.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EKX48546.1 - 1.9e-05 24.8 0.0 2.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 EKX48546.1 - 2.8e-05 23.8 0.0 3.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 EKX48546.1 - 0.0018 18.0 0.0 0.0029 17.3 0.0 1.4 1 1 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase2 PF03162.13 EKX48546.1 - 0.17 11.5 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Ank_5 PF13857.6 EKX48547.1 - 1.9e-08 34.4 0.1 3.5e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX48547.1 - 0.00015 22.3 0.5 0.00044 20.8 0.2 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX48547.1 - 0.0053 17.2 0.2 0.012 16.0 0.2 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 EKX48547.1 - 0.007 16.9 0.3 0.025 15.2 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF2203 PF09969.9 EKX48549.1 - 0.16 12.7 10.9 0.35 11.6 3.3 3.7 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2203) KIP1 PF07765.12 EKX48549.1 - 0.61 10.2 11.0 3.7 7.7 2.1 3.1 2 1 1 3 3 3 0 KIP1-like protein SLED PF12140.8 EKX48549.1 - 3.1 8.3 5.1 2.9 8.4 0.8 2.6 2 1 0 2 2 2 0 SLED domain ESM4 PF15952.5 EKX48549.1 - 8.6 6.7 10.2 21 5.5 10.2 1.8 1 0 0 1 1 1 0 Enhancer of split M4 family TPR_12 PF13424.6 EKX48550.1 - 2.8e-17 62.7 10.7 1.4e-06 28.5 0.4 4.5 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 EKX48550.1 - 6.4e-13 47.8 12.5 0.08 13.2 0.3 6.0 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 EKX48550.1 - 5.1e-10 38.7 9.7 0.07 13.0 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 EKX48550.1 - 1.4e-08 34.2 10.9 1.1 9.4 0.1 6.3 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EKX48550.1 - 6.1e-08 32.2 12.9 0.74 10.1 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 EKX48550.1 - 0.00053 20.6 3.6 15 6.7 0.0 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat SUIM_assoc PF16619.5 EKX48550.1 - 0.0048 16.9 5.2 0.043 13.9 2.5 2.7 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 TPR_10 PF13374.6 EKX48550.1 - 0.019 14.8 4.5 35 4.4 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1178 PF06676.11 EKX48550.1 - 0.097 13.1 2.7 0.1 13.0 1.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1178) TPR_6 PF13174.6 EKX48550.1 - 0.31 11.8 5.2 1.2e+02 3.6 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Kinesin PF00225.23 EKX48551.1 - 2.7e-96 322.4 0.0 3.4e-96 322.1 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX48551.1 - 2.2e-19 69.9 0.0 5.4e-19 68.6 0.0 1.7 2 0 0 2 2 2 1 Microtubule binding FKBP_C PF00254.28 EKX48552.1 - 1.5e-18 66.9 0.0 2.2e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase POTRA PF07244.15 EKX48554.1 - 1.1 9.8 7.4 69 4.1 0.1 4.2 3 1 0 3 3 3 0 Surface antigen variable number repeat SPRY PF00622.28 EKX48555.1 - 0.025 14.7 0.1 0.044 13.9 0.1 1.3 1 0 0 1 1 1 0 SPRY domain SET PF00856.28 EKX48555.1 - 1.6 9.1 6.8 5.3 7.4 6.7 1.9 1 1 0 1 1 1 0 SET domain TSSC4 PF15264.6 EKX48556.1 - 0.041 14.1 0.0 0.05 13.9 0.0 1.3 1 1 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 SASA PF03629.18 EKX48557.1 - 6.5e-16 58.7 0.0 1.3e-14 54.4 0.0 2.8 2 1 0 2 2 2 1 Carbohydrate esterase, sialic acid-specific acetylesterase 40S_S4_C PF16121.5 EKX48557.1 - 0.092 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 40S ribosomal protein S4 C-terminus BACK PF07707.15 EKX48558.1 - 8.8e-14 51.5 1.3 1.5e-12 47.5 1.3 2.4 1 1 0 1 1 1 1 BTB And C-terminal Kelch PX PF00787.24 EKX48558.1 - 2.1e-13 50.3 0.1 4.7e-13 49.1 0.1 1.6 1 0 0 1 1 1 1 PX domain PDZ PF00595.24 EKX48558.1 - 0.00037 20.8 0.1 0.00085 19.6 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX48558.1 - 0.00055 20.2 0.1 0.0022 18.3 0.1 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EKX48558.1 - 0.0044 16.8 0.1 0.017 15.0 0.0 2.1 1 1 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX48558.1 - 0.076 13.0 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 Tricorn protease PDZ domain Chloroa_b-bind PF00504.21 EKX48559.1 - 2.1e-36 125.9 0.1 2.8e-36 125.5 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein PARP PF00644.20 EKX48560.1 - 1.3e-25 90.1 0.0 3.5e-24 85.5 0.0 2.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain GvpK PF05121.12 EKX48562.1 - 0.092 12.8 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Gas vesicle protein K ABC_trans_N PF14510.6 EKX48563.1 - 0.12 13.0 2.2 0.25 12.0 0.1 2.2 2 1 0 2 2 2 0 ABC-transporter N-terminal Sulfate_transp PF00916.20 EKX48565.1 - 3.4e-47 161.0 12.8 5.1e-47 160.4 12.8 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EKX48565.1 - 0.00016 21.3 0.0 0.00044 19.9 0.0 1.7 1 1 0 1 1 1 1 STAS domain Beta_helix PF13229.6 EKX48566.1 - 7.4e-06 25.9 0.2 1.2e-05 25.2 0.2 1.3 1 0 0 1 1 1 1 Right handed beta helix region Nucleoside_tran PF01733.18 EKX48568.1 - 3.4e-10 39.8 1.7 3.4e-10 39.8 1.7 2.8 2 1 0 2 2 2 1 Nucleoside transporter Trypsin_2 PF13365.6 EKX48571.1 - 2.5e-30 106.4 1.2 2.5e-30 106.4 1.2 1.8 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 EKX48571.1 - 5.8e-18 65.5 0.6 1.9e-17 63.8 0.1 1.9 1 1 1 2 2 2 1 Trypsin PDZ_2 PF13180.6 EKX48571.1 - 1e-11 45.0 0.0 2.6e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX48571.1 - 8.1e-09 35.2 0.2 3.3e-08 33.2 0.2 2.0 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX48571.1 - 1.4e-06 28.5 0.1 3.4e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX48571.1 - 0.00012 21.9 0.1 0.00033 20.6 0.1 1.7 1 0 0 1 1 1 1 Tricorn protease PDZ domain Peptidase_S32 PF05579.13 EKX48571.1 - 0.013 14.7 1.0 1.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Peptidase_S46 PF10459.9 EKX48571.1 - 0.013 14.1 2.2 0.13 10.9 0.2 2.1 2 0 0 2 2 2 0 Peptidase S46 GRASP55_65 PF04495.14 EKX48571.1 - 0.079 13.3 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain C2 PF00168.30 EKX48572.1 - 1.8e-27 95.6 0.1 1.8e-10 41.0 0.1 8.0 9 0 0 9 9 9 3 C2 domain Ferlin_C PF16165.5 EKX48572.1 - 0.027 14.4 0.0 0.027 14.4 0.0 3.7 2 1 1 3 3 3 0 Ferlin C-terminus EMG1 PF03587.14 EKX48572.1 - 0.08 12.6 0.2 0.2 11.3 0.2 1.6 1 0 0 1 1 1 0 EMG1/NEP1 methyltransferase VSG_B PF13206.6 EKX48572.1 - 4.1 6.5 22.8 9.6 5.4 22.8 1.6 1 0 0 1 1 1 0 Trypanosomal VSG domain Es2 PF09751.9 EKX48573.1 - 1.7e-50 173.1 9.2 3.6e-34 119.2 0.0 3.0 1 1 2 3 3 3 2 Nuclear protein Es2 Ephrin_rec_like PF07699.13 EKX48574.1 - 8.1e-09 35.1 40.9 8.7e-05 22.2 1.3 4.9 2 1 3 5 5 5 5 Putative ephrin-receptor like NCD3G PF07562.14 EKX48574.1 - 0.00076 19.4 35.3 0.14 12.1 2.2 5.3 4 1 1 5 5 5 4 Nine Cysteines Domain of family 3 GPCR DUF4381 PF14316.6 EKX48575.1 - 0.049 13.9 1.0 0.049 13.9 1.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Transposase_24 PF03004.14 EKX48575.1 - 0.12 12.4 0.3 0.12 12.4 0.3 2.7 2 1 1 3 3 3 0 Plant transposase (Ptta/En/Spm family) FtsL PF04999.13 EKX48575.1 - 0.16 12.0 4.6 0.64 10.1 4.6 2.1 1 1 0 1 1 1 0 Cell division protein FtsL LapA_dom PF06305.11 EKX48575.1 - 0.32 10.8 4.1 5.7 6.8 0.0 2.7 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF4446 PF14584.6 EKX48575.1 - 1.8 8.5 6.8 0.41 10.6 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF4404 PF14357.6 EKX48575.1 - 3.4 8.4 8.4 1.2 9.9 1.1 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF3294 PF07957.11 EKX48575.1 - 6.8 6.4 11.5 23 4.6 11.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3294) HECA PF15353.6 EKX48577.1 - 0.00014 22.0 1.6 0.37 11.0 0.0 3.1 3 0 0 3 3 3 2 Headcase protein family homologue LIM PF00412.22 EKX48577.1 - 0.00069 19.8 17.3 0.031 14.5 0.3 3.3 3 0 0 3 3 3 2 LIM domain C1_1 PF00130.22 EKX48577.1 - 0.00072 19.4 8.0 0.84 9.6 0.3 3.5 3 1 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) WW PF00397.26 EKX48577.1 - 0.0011 19.0 0.1 0.0045 17.1 0.1 2.1 1 0 0 1 1 1 1 WW domain Insulin PF00049.18 EKX48577.1 - 0.0055 17.7 4.0 0.53 11.3 0.2 3.2 3 0 0 3 3 3 1 Insulin/IGF/Relaxin family zf-PARP PF00645.18 EKX48577.1 - 0.0066 17.3 3.6 3.9 8.4 0.0 3.4 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region MTHFR_C PF12225.8 EKX48577.1 - 0.23 11.1 3.2 6.4 6.5 0.3 2.5 2 0 0 2 2 2 0 Methylene-tetrahydrofolate reductase C terminal DZR PF12773.7 EKX48577.1 - 0.74 9.9 9.5 6.5 6.9 0.3 3.3 3 0 0 3 3 3 0 Double zinc ribbon DUF2175 PF09943.9 EKX48577.1 - 0.85 9.9 7.5 1.6 9.1 0.2 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C2HC5 PF06221.13 EKX48577.1 - 0.88 9.6 6.4 13 5.8 0.1 3.3 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type zf-RING_2 PF13639.6 EKX48577.1 - 1.4 9.3 10.7 17 5.8 0.5 3.3 3 0 0 3 3 3 0 Ring finger domain Cript PF10235.9 EKX48577.1 - 3.6 8.2 10.7 1.2 9.7 0.3 3.5 3 1 0 4 4 3 0 Microtubule-associated protein CRIPT Ribosomal_L37e PF01907.19 EKX48577.1 - 5.4 7.3 10.2 8.6 6.6 2.3 2.6 2 0 0 2 2 2 0 Ribosomal protein L37e C1_2 PF03107.16 EKX48577.1 - 7.2 7.0 8.6 5.3 7.4 1.1 3.1 3 0 0 3 3 3 0 C1 domain zf-LITAF-like PF10601.9 EKX48577.1 - 7.3 6.9 8.8 4.9 7.5 0.2 3.1 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain Arb2 PF09757.9 EKX48578.1 - 2.5e-05 23.5 0.0 0.00017 20.8 0.0 1.9 1 1 0 1 1 1 1 Arb2 domain Hydrolase_4 PF12146.8 EKX48578.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 EKX48578.1 - 0.1 11.4 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase DUF2856 PF11043.8 EKX48578.1 - 0.17 12.0 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2856) Pkinase_Tyr PF07714.17 EKX48579.1 - 2.3e-24 86.1 0.0 2.6e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX48579.1 - 4.3e-22 78.8 0.0 4.8e-22 78.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EKX48579.1 - 0.1 11.9 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Kinase-like TLD PF07534.16 EKX48580.1 - 1.7e-25 89.8 0.4 2.8e-25 89.2 0.4 1.3 1 0 0 1 1 1 1 TLD HlyD_D4 PF16572.5 EKX48580.1 - 0.036 13.9 0.1 0.077 12.9 0.1 1.5 1 0 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB DUF2236 PF09995.9 EKX48580.1 - 0.086 13.0 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) Cyclin_C_2 PF16899.5 EKX48581.1 - 2.3e-10 40.8 0.1 6.7e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 EKX48581.1 - 1.3e-07 31.4 0.1 3e-07 30.2 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain SNF2_N PF00176.23 EKX48582.1 - 8.2e-45 153.0 0.1 2.1e-44 151.7 0.0 1.7 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX48582.1 - 2.2e-14 53.7 0.0 4.5e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EKX48582.1 - 3.6e-07 29.6 0.0 5.6e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 EKX48582.1 - 0.03 14.3 0.0 1.1 9.3 0.0 2.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Ank_2 PF12796.7 EKX48583.1 - 5.3e-21 75.0 8.4 9.6e-12 45.3 0.9 2.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX48583.1 - 1.7e-17 63.5 5.7 1.4e-11 44.6 0.4 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX48583.1 - 1.3e-12 47.6 5.5 3.9e-07 30.2 1.7 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX48583.1 - 3e-12 45.6 2.6 0.00095 19.5 0.1 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 EKX48583.1 - 4e-10 39.7 6.9 0.00041 20.7 0.3 3.6 3 0 0 3 3 3 3 Ankyrin repeat NUDIX PF00293.28 EKX48584.1 - 7.5e-17 61.6 0.0 1e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Frankia_peptide PF14407.6 EKX48584.1 - 0.038 14.0 0.3 1.1 9.3 0.1 2.5 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. RWP-RK PF02042.15 EKX48585.1 - 3.5e-15 55.7 0.0 5.7e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain PKD_channel PF08016.12 EKX48586.1 - 3.2e-31 108.5 20.3 4.7e-29 101.3 18.4 3.3 2 1 0 2 2 2 2 Polycystin cation channel Ion_trans PF00520.31 EKX48586.1 - 2.4e-12 46.6 15.9 2.4e-12 46.6 15.9 2.2 2 0 0 2 2 2 1 Ion transport protein PDR_CDR PF06422.12 EKX48586.1 - 1.7 8.6 3.9 12 5.9 0.1 2.7 2 0 0 2 2 2 0 CDR ABC transporter WD40 PF00400.32 EKX48587.1 - 3.7e-26 90.9 11.4 1.5e-07 32.0 0.2 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX48587.1 - 4.4e-07 30.1 0.0 0.11 12.7 0.0 4.3 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EKX48587.1 - 0.0034 16.8 0.0 0.0066 15.8 0.0 1.5 2 0 0 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 EKX48587.1 - 0.027 13.4 0.1 0.67 8.9 0.0 2.8 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CzcE PF16986.5 EKX48587.1 - 0.23 11.8 0.3 14 6.1 0.0 2.9 3 0 0 3 3 3 0 Heavy-metal resistance protein CzcE DNA_pol_A PF00476.20 EKX48589.1 - 1.5e-58 198.7 5.6 3e-41 141.7 0.0 3.3 1 1 2 3 3 3 3 DNA polymerase family A ABC_tran PF00005.27 EKX48589.1 - 1.1e-36 126.3 2.9 1.3e-19 71.1 0.0 3.4 3 0 0 3 3 2 2 ABC transporter DEAD PF00270.29 EKX48589.1 - 4e-16 59.3 0.5 3.5e-13 49.7 0.4 3.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX48589.1 - 4.4e-11 43.1 0.0 9.3e-10 38.8 0.0 3.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_21 PF13304.6 EKX48589.1 - 6.6e-10 39.3 0.3 0.019 14.8 0.0 4.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EKX48589.1 - 2.7e-07 30.2 0.1 0.015 15.1 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EKX48589.1 - 4.1e-06 26.8 0.0 0.046 13.6 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EKX48589.1 - 2.4e-05 24.4 0.1 0.047 13.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.6 EKX48589.1 - 4.1e-05 23.2 0.0 0.26 10.8 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EKX48589.1 - 8e-05 22.9 0.5 3.4 7.9 0.0 4.8 3 2 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 EKX48589.1 - 0.00015 21.1 0.0 0.67 9.2 0.0 2.8 2 0 0 2 2 2 2 Zeta toxin SRP54 PF00448.22 EKX48589.1 - 0.00032 20.4 0.1 0.046 13.3 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 EKX48589.1 - 0.0014 19.1 7.2 0.4 11.0 0.1 4.1 3 0 0 3 3 3 2 AAA ATPase domain SMC_N PF02463.19 EKX48589.1 - 0.0028 17.1 1.4 3.1 7.2 0.2 4.0 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain MeaB PF03308.16 EKX48589.1 - 0.0029 16.6 0.0 2.1 7.3 0.0 2.9 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 EKX48589.1 - 0.0037 17.2 0.0 4.4 7.2 0.0 3.0 2 0 0 2 2 2 1 NACHT domain ATP-synt_ab PF00006.25 EKX48589.1 - 0.0088 15.7 0.0 0.1 12.2 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain SpoIIP PF07454.11 EKX48589.1 - 0.036 13.5 4.7 0.11 12.0 4.7 1.7 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DAP3 PF10236.9 EKX48589.1 - 0.04 13.1 0.1 6 5.9 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Arf PF00025.21 EKX48589.1 - 0.064 12.7 0.0 7.7 5.9 0.0 2.7 2 0 0 2 2 2 0 ADP-ribosylation factor family SPATA3 PF15662.5 EKX48589.1 - 0.07 13.8 0.2 0.07 13.8 0.2 2.4 2 0 0 2 2 2 0 Spermatogenesis-associated protein 3 family AAA_15 PF13175.6 EKX48589.1 - 0.095 12.4 6.6 1 9.0 0.0 3.6 4 0 0 4 4 4 0 AAA ATPase domain AAA_14 PF13173.6 EKX48589.1 - 0.14 12.2 0.0 29 4.7 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA PF00004.29 EKX48589.1 - 0.15 12.4 0.0 75 3.7 0.0 4.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EKX48589.1 - 0.17 11.6 0.0 19 4.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EKX48589.1 - 0.18 12.4 2.9 11 6.6 0.0 4.0 3 0 0 3 3 2 0 AAA domain Connexin PF00029.19 EKX48589.1 - 0.19 11.5 4.7 0.87 9.3 4.7 2.2 1 0 0 1 1 1 0 Connexin Dynamin_N PF00350.23 EKX48589.1 - 0.3 11.1 8.4 4.4 7.3 0.0 3.7 3 0 0 3 3 3 0 Dynamin family DUF4518 PF15008.6 EKX48589.1 - 0.64 9.2 3.8 0.69 9.0 2.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) AAA_23 PF13476.6 EKX48589.1 - 0.66 10.4 0.0 0.66 10.4 0.0 5.1 5 0 0 5 5 5 0 AAA domain ESM4 PF15952.5 EKX48589.1 - 0.95 9.9 10.9 0.042 14.3 4.0 2.4 2 0 0 2 2 1 0 Enhancer of split M4 family AAA_28 PF13521.6 EKX48589.1 - 2.5 8.3 14.9 1.7 8.8 0.0 5.1 4 0 0 4 4 3 0 AAA domain AAA_33 PF13671.6 EKX48589.1 - 2.6 8.2 7.2 15 5.7 0.0 3.7 4 0 0 4 4 3 0 AAA domain NARP1 PF12569.8 EKX48589.1 - 3.2 6.6 12.4 8.1 5.2 12.4 1.6 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Zip PF02535.22 EKX48589.1 - 7.1 5.8 5.4 18 4.4 5.4 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter EF-hand_1 PF00036.32 EKX48591.1 - 0.0011 18.4 0.1 0.011 15.2 0.0 2.4 2 0 0 2 2 2 1 EF hand p25-alpha PF05517.12 EKX48591.1 - 0.0042 17.2 0.0 0.13 12.4 0.0 3.1 3 0 0 3 3 3 1 p25-alpha Mst1_SARAH PF11629.8 EKX48591.1 - 0.0046 17.0 7.8 0.63 10.2 2.8 2.9 2 0 0 2 2 2 2 C terminal SARAH domain of Mst1 EF-hand_7 PF13499.6 EKX48591.1 - 0.024 15.1 0.2 0.32 11.5 0.1 2.8 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 EKX48591.1 - 0.066 13.2 0.1 0.83 9.8 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain Thioredoxin PF00085.20 EKX48592.1 - 1.5e-21 76.3 0.1 1.8e-21 76.1 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EKX48592.1 - 3e-05 24.1 0.1 4.7e-05 23.5 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EKX48592.1 - 0.00063 20.2 0.0 0.0016 18.9 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EKX48592.1 - 0.0055 16.5 0.0 0.0079 16.0 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EKX48592.1 - 0.021 15.2 0.0 1.7 9.0 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin-like OST3_OST6 PF04756.13 EKX48592.1 - 0.024 14.0 0.0 0.025 13.9 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EKX48592.1 - 0.027 14.4 0.1 0.033 14.1 0.1 1.3 1 1 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.10 EKX48592.1 - 0.061 13.0 0.2 0.15 11.7 0.2 1.7 1 1 0 1 1 1 0 Redoxin Tli4_N PF18443.1 EKX48593.1 - 0.055 13.8 0.1 0.086 13.2 0.1 1.3 1 0 0 1 1 1 0 Tle cognate immunity protein 4 N-terminal domain Alpha_kinase PF02816.18 EKX48594.1 - 2e-53 181.2 0.0 3.1e-53 180.6 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family zf-C2H2_4 PF13894.6 EKX48594.1 - 4.7 8.3 5.7 1.3 10.0 1.5 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Pkinase PF00069.25 EKX48597.1 - 6.7e-51 173.2 0.0 7.9e-51 172.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX48597.1 - 1.2e-34 119.8 0.0 1.5e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX48597.1 - 0.0043 16.4 0.7 0.052 12.9 0.3 2.4 1 1 1 2 2 2 1 Kinase-like PWWP PF00855.17 EKX48598.1 - 0.0018 18.7 0.3 0.0038 17.6 0.3 1.7 1 1 0 1 1 1 1 PWWP domain Tudor_4 PF18358.1 EKX48598.1 - 0.015 14.9 0.3 0.048 13.3 0.1 1.8 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain Aldo_ket_red PF00248.21 EKX48599.1 - 6.3e-57 193.0 0.0 1.2e-44 152.7 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Peptidase_M1 PF01433.20 EKX48600.1 - 2e-84 282.5 0.7 3e-84 281.9 0.7 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 EKX48600.1 - 5.1e-82 275.9 0.4 9e-82 275.1 0.4 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 EKX48600.1 - 1.8e-46 158.7 0.0 3.4e-46 157.8 0.0 1.5 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain DUF3876 PF12992.7 EKX48600.1 - 0.16 12.1 0.0 16 5.7 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF3876) Sulfotransfer_3 PF13469.6 EKX48601.1 - 7.6e-10 39.5 1.0 0.00013 22.4 0.8 3.5 2 1 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 EKX48601.1 - 2.8e-08 33.6 0.0 2.5e-07 30.4 0.0 2.3 1 1 0 1 1 1 1 Sulfotransferase domain DnaJ PF00226.31 EKX48602.1 - 5.1e-09 36.1 0.1 3e-08 33.6 0.0 2.4 2 0 0 2 2 2 1 DnaJ domain WW PF00397.26 EKX48602.1 - 1.3e-06 28.4 7.2 0.00026 21.0 0.3 2.9 3 0 0 3 3 3 2 WW domain Biopterin_H PF00351.21 EKX48603.1 - 6.2e-134 446.2 0.0 7.6e-134 445.9 0.0 1.0 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase Ribosomal_L28e PF01778.17 EKX48604.1 - 9.2e-40 136.0 1.2 9.2e-40 136.0 1.2 1.6 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 EKX48604.1 - 2.6e-24 85.7 40.9 3.8e-24 85.2 32.0 3.4 2 1 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 EKX48604.1 - 3.4e-08 33.3 18.5 4.6e-08 32.8 18.5 1.1 1 0 0 1 1 1 1 BUD22 DUF4604 PF15377.6 EKX48604.1 - 0.07 13.6 19.3 0.11 12.9 19.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) LTV PF04180.14 EKX48604.1 - 0.27 11.0 23.3 0.47 10.1 23.3 1.3 1 0 0 1 1 1 0 Low temperature viability protein TFIIF_alpha PF05793.12 EKX48604.1 - 0.37 9.3 32.7 0.53 8.8 32.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 EKX48604.1 - 1 7.6 25.7 1.7 6.8 25.7 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF4820 PF16091.5 EKX48604.1 - 1.4 8.3 11.9 0.016 14.6 1.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4820) Phage_1_1 PF08200.11 EKX48604.1 - 6.1 7.3 8.5 0.91 10.0 1.7 2.9 2 0 0 2 2 2 0 Bacteriophage 1.1 Protein Mito_carr PF00153.27 EKX48605.1 - 7.7e-46 154.0 2.1 2.5e-16 59.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Carb_kinase PF01256.17 EKX48606.1 - 3.7e-50 170.7 0.0 4.6e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase HALZ PF02183.18 EKX48607.1 - 1.4e-05 25.2 7.3 0.015 15.5 2.1 2.6 2 0 0 2 2 2 2 Homeobox associated leucine zipper ZapB PF06005.12 EKX48607.1 - 0.0026 18.2 9.4 0.19 12.2 4.7 2.4 2 0 0 2 2 2 2 Cell division protein ZapB Sipho_Gp157 PF05565.11 EKX48607.1 - 0.0054 16.8 2.5 0.81 9.7 0.9 2.2 2 0 0 2 2 2 2 Siphovirus Gp157 ParB PF08775.10 EKX48607.1 - 0.022 15.3 1.6 0.6 10.6 0.3 2.2 2 0 0 2 2 2 0 ParB family DUF2353 PF09789.9 EKX48607.1 - 0.031 13.6 3.9 0.1 12.0 3.9 1.7 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) DUF3450 PF11932.8 EKX48607.1 - 0.089 12.1 3.3 4.4 6.5 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) S10_plectin PF03501.15 EKX48607.1 - 0.16 12.0 0.3 25 5.0 0.0 2.3 2 0 0 2 2 2 0 Plectin/S10 domain SHE3 PF17078.5 EKX48607.1 - 0.19 11.5 3.6 4.3 7.0 0.1 2.2 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 JIP_LZII PF16471.5 EKX48607.1 - 0.2 11.8 6.4 0.29 11.3 0.2 2.7 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF1664 PF07889.12 EKX48607.1 - 0.23 11.5 3.1 12 6.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Myc-LZ PF02344.15 EKX48607.1 - 0.54 10.4 4.2 2.4 8.3 0.4 2.5 2 0 0 2 2 2 0 Myc leucine zipper domain CENP-H PF05837.12 EKX48607.1 - 0.76 10.2 7.9 0.69 10.3 3.0 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) TPR_MLP1_2 PF07926.12 EKX48607.1 - 3 7.9 9.1 2.4 8.2 4.9 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Nup88 PF10168.9 EKX48607.1 - 4.2 5.1 5.1 2.2 6.0 0.0 2.0 2 0 0 2 2 2 0 Nuclear pore component HK PF02110.15 EKX48608.1 - 0.14 11.5 0.0 1.4 8.2 0.0 2.1 2 0 0 2 2 2 0 Hydroxyethylthiazole kinase family DUF4407 PF14362.6 EKX48608.1 - 0.28 10.5 22.5 1 8.7 3.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Vps51 PF08700.11 EKX48608.1 - 0.53 10.4 10.5 20 5.4 0.1 4.8 4 1 0 4 4 4 0 Vps51/Vps67 Het-C PF07217.11 EKX48608.1 - 0.55 8.7 10.8 0.064 11.8 0.9 2.2 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C Cyclin_N PF00134.23 EKX48609.1 - 2.4e-48 163.1 2.2 2.4e-48 163.1 2.2 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EKX48609.1 - 4e-31 107.6 1.6 7.4e-31 106.7 1.6 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Aldo_ket_red PF00248.21 EKX48610.1 - 1e-23 84.0 0.0 2.7e-20 72.8 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family XPG_N PF00752.17 EKX48611.1 - 0.00034 21.0 0.0 0.00045 20.6 0.0 1.2 1 0 0 1 1 1 1 XPG N-terminal domain MatE PF01554.18 EKX48612.1 - 1.1e-27 96.7 8.8 1.1e-27 96.7 8.8 1.5 2 0 0 2 2 2 1 MatE Kinesin PF00225.23 EKX48613.1 - 1.2e-32 113.1 0.0 2.6e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX48613.1 - 5.3e-20 71.9 0.0 1.5e-19 70.4 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding TBP PF00352.21 EKX48613.1 - 3.6e-09 36.4 0.1 4.9e-05 23.2 0.0 2.7 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) Ank_5 PF13857.6 EKX48613.1 - 2.7e-05 24.3 0.1 0.00012 22.3 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Phage_TAC_3 PF06896.11 EKX48613.1 - 0.00061 20.4 2.0 0.0025 18.4 2.0 2.1 1 0 0 1 1 1 1 Phage tail assembly chaperone proteins, TAC Ank_2 PF12796.7 EKX48613.1 - 0.0011 19.6 0.0 0.0028 18.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX48613.1 - 0.01 16.3 0.0 0.058 14.0 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat Ank PF00023.30 EKX48613.1 - 0.029 14.8 0.0 0.071 13.6 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat WD40 PF00400.32 EKX48614.1 - 2e-06 28.4 3.2 0.076 13.9 0.2 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat CENP-B_dimeris PF09026.10 EKX48614.1 - 0.055 13.9 0.7 0.094 13.1 0.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pkinase PF00069.25 EKX48615.1 - 1.9e-18 66.8 0.0 2.5e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX48615.1 - 3.2e-10 39.7 0.0 4.5e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX48615.1 - 9.2e-06 25.7 0.0 1.4e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family TPR_2 PF07719.17 EKX48617.1 - 1.8e-26 90.0 0.1 0.00064 19.6 0.0 6.1 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_14 PF13428.6 EKX48617.1 - 1.7e-21 75.0 2.5 0.002 18.8 0.1 6.1 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 EKX48617.1 - 5.6e-18 63.6 0.0 0.057 13.6 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX48617.1 - 2.8e-16 59.6 6.7 0.00034 20.9 0.1 5.6 2 2 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 EKX48617.1 - 4e-16 58.2 0.0 0.0096 16.2 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX48617.1 - 5.4e-16 57.7 0.0 0.0019 17.9 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 EKX48617.1 - 5.2e-15 55.7 0.0 4e-05 24.0 0.0 3.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX48617.1 - 8.2e-13 48.8 1.3 0.0012 19.4 0.0 5.0 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 EKX48617.1 - 2.3e-12 46.0 0.0 0.12 12.5 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX48617.1 - 8.2e-11 41.4 0.0 0.29 10.8 0.0 5.7 5 1 1 6 6 6 2 TPR repeat TPR_9 PF13371.6 EKX48617.1 - 1.5e-07 31.4 0.1 0.03 14.5 0.0 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EKX48617.1 - 1.6e-07 31.3 0.1 4.4 7.3 0.0 4.4 4 1 0 4 4 4 3 Mad3/BUB1 homology region 1 TPR_15 PF13429.6 EKX48617.1 - 1.8e-07 30.6 0.4 0.00041 19.6 0.0 3.2 1 1 3 4 4 4 1 Tetratricopeptide repeat MIT PF04212.18 EKX48617.1 - 5.9e-06 26.3 0.8 9.9 6.3 0.0 5.4 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 EKX48617.1 - 1.1e-05 25.8 0.7 7 7.5 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 EKX48617.1 - 3.4e-05 24.1 0.8 1 10.2 0.3 4.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX48617.1 - 4.2e-05 23.3 7.4 0.6 10.1 0.2 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX48617.1 - 0.00054 20.1 0.0 0.075 13.3 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 EKX48617.1 - 0.0013 17.8 0.0 0.27 10.1 0.0 2.3 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 DUF4810 PF16068.5 EKX48617.1 - 0.023 15.2 2.2 26 5.5 0.0 3.9 2 1 2 4 4 4 0 Domain of unknown function (DUF4810) DUF3390 PF11870.8 EKX48617.1 - 0.032 14.6 0.3 11 6.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3390) TPR_3 PF07720.12 EKX48617.1 - 0.06 13.4 0.0 14 5.8 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1353 PF07087.11 EKX48617.1 - 0.068 12.9 0.0 11 5.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1353) Fis1_TPR_C PF14853.6 EKX48617.1 - 0.075 13.1 0.9 1.4e+02 2.6 0.0 4.6 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.20 EKX48617.1 - 0.22 11.8 3.9 81 3.8 0.1 4.9 6 0 0 6 6 5 0 PPR repeat HemY_N PF07219.13 EKX48617.1 - 0.98 9.7 7.0 15 5.9 0.1 4.2 2 2 3 5 5 5 0 HemY protein N-terminus DUF268 PF03269.14 EKX48620.1 - 6.4e-34 117.3 0.0 1.2e-33 116.5 0.0 1.4 1 0 0 1 1 1 1 Caenorhabditis protein of unknown function, DUF268 SDA1 PF05285.12 EKX48620.1 - 0.00017 21.1 44.3 0.00024 20.7 44.3 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 EKX48620.1 - 0.07 11.3 45.9 0.11 10.7 45.9 1.2 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 EKX48620.1 - 0.23 10.2 9.6 0.32 9.8 9.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NPR3 PF03666.13 EKX48620.1 - 3 6.5 5.7 4.9 5.8 5.7 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Molydop_binding PF01568.21 EKX48622.1 - 0.042 13.9 0.0 0.51 10.4 0.0 2.3 2 0 0 2 2 2 0 Molydopterin dinucleotide binding domain SAM_1 PF00536.30 EKX48624.1 - 5.8e-16 58.7 0.8 6.5e-15 55.3 0.1 2.6 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EKX48624.1 - 1.1e-14 54.2 0.1 3.7e-14 52.6 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 EKX48624.1 - 9.3e-05 22.3 0.1 0.00025 20.9 0.0 1.7 1 1 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain DUF1700 PF08006.11 EKX48624.1 - 0.24 10.9 1.0 0.53 9.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) PKcGMP_CC PF16808.5 EKX48624.1 - 3.4 7.6 10.6 0.19 11.6 1.6 3.3 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase MAPEG PF01124.18 EKX48625.1 - 9.9e-24 83.7 0.3 1.2e-23 83.4 0.3 1.1 1 0 0 1 1 1 1 MAPEG family LSDAT_euk PF18139.1 EKX48626.1 - 2.1e-31 109.3 0.2 1.6e-30 106.4 0.2 2.2 1 1 0 1 1 1 1 SLOG in TRPM LSDAT_prok PF18171.1 EKX48626.1 - 1.2e-24 86.7 0.3 2.1e-23 82.6 0.1 2.5 2 1 0 2 2 2 1 SLOG in TRPM, prokaryote Ion_trans PF00520.31 EKX48626.1 - 7.9e-18 64.6 27.5 1.8e-17 63.4 27.5 1.5 1 0 0 1 1 1 1 Ion transport protein Chloroa_b-bind PF00504.21 EKX48627.1 - 2.3e-39 135.5 0.2 3.2e-39 135.0 0.2 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein He_PIG PF05345.12 EKX48628.1 - 2.3e-36 123.7 23.6 3.7e-05 23.8 1.1 9.4 9 0 0 9 9 9 9 Putative Ig domain Glutaredoxin PF00462.24 EKX48629.1 - 2.8e-20 72.3 0.0 4.8e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 EKX48629.1 - 0.0051 17.2 0.0 0.02 15.3 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.6 EKX48629.1 - 0.025 15.0 0.0 0.034 14.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain GST_N_3 PF13417.6 EKX48629.1 - 0.038 14.4 0.0 0.051 14.0 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DSBA PF01323.20 EKX48629.1 - 0.039 13.7 2.0 0.33 10.7 0.1 2.2 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 EKX48629.1 - 0.081 13.0 0.0 0.16 12.0 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin domain FHA PF00498.26 EKX48630.1 - 4.3e-16 59.0 0.0 9.9e-16 57.9 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EKX48630.1 - 1.1e-07 32.0 0.0 3e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Rho_RNA_bind PF07497.12 EKX48630.1 - 0.023 14.6 0.5 1.3 8.9 0.0 2.9 2 1 0 2 2 2 0 Rho termination factor, RNA-binding domain Malt_amylase_C PF16657.5 EKX48630.1 - 0.11 12.6 0.2 2.1 8.5 0.0 2.4 2 0 0 2 2 2 0 Maltogenic Amylase, C-terminal domain DUF3600 PF12207.8 EKX48631.1 - 3.5e-06 27.0 11.4 0.098 12.6 0.3 4.5 2 2 2 4 4 4 3 Domain of unknown function (DUF3600) Caskin-tail PF16632.5 EKX48631.1 - 0.00023 21.5 5.7 4.1 7.9 0.2 4.9 3 1 2 5 5 5 2 C-terminal region of Caskin DUF4429 PF14472.6 EKX48631.1 - 1 10.0 5.1 3 8.5 0.3 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4429) LAGLIDADG_1 PF00961.19 EKX48631.1 - 3.5 8.7 8.2 7.6 7.6 4.3 3.0 2 1 1 3 3 3 0 LAGLIDADG endonuclease LXG PF04740.12 EKX48632.1 - 0.048 13.4 0.4 0.074 12.7 0.1 1.4 1 1 0 1 1 1 0 LXG domain of WXG superfamily Sirohm_synth_C PF14823.6 EKX48632.1 - 0.16 11.6 1.8 0.17 11.5 0.4 1.8 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal Lectin_N PF03954.14 EKX48632.1 - 0.49 10.1 2.2 13 5.5 0.1 2.2 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF4472 PF14739.6 EKX48632.1 - 4.6 8.0 9.2 3.8 8.3 5.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) PAN_4 PF14295.6 EKX48633.1 - 5.1e-17 61.5 3.1 1.4e-07 31.3 0.6 2.4 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.11 EKX48633.1 - 0.00047 20.2 4.7 0.093 12.9 0.3 2.4 2 0 0 2 2 2 2 PAN-like domain MANEC PF07502.14 EKX48633.1 - 0.022 15.0 0.9 2.5 8.4 0.3 2.2 2 0 0 2 2 2 0 MANEC domain PAN_4 PF14295.6 EKX48635.1 - 3.6e-17 62.0 3.2 1.1e-07 31.7 0.6 2.3 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.11 EKX48635.1 - 0.00044 20.3 4.9 0.096 12.8 0.4 2.4 2 0 0 2 2 2 2 PAN-like domain MANEC PF07502.14 EKX48635.1 - 0.011 15.9 1.2 1.4 9.3 0.3 2.2 2 0 0 2 2 2 0 MANEC domain DUF2272 PF10030.9 EKX48635.1 - 0.11 12.3 0.1 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2272) PAN_4 PF14295.6 EKX48637.1 - 3.1e-17 62.2 3.1 1.1e-07 31.7 0.6 2.3 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.11 EKX48637.1 - 0.00031 20.8 4.8 0.071 13.2 0.3 2.4 2 0 0 2 2 2 2 PAN-like domain MANEC PF07502.14 EKX48637.1 - 0.041 14.2 2.4 3 8.2 0.8 2.2 2 0 0 2 2 2 0 MANEC domain DUF2272 PF10030.9 EKX48637.1 - 0.078 12.7 0.1 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2272) NYN PF01936.18 EKX48638.1 - 3.9e-08 33.9 0.0 8.7e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 NYN domain HpcH_HpaI PF03328.14 EKX48639.1 - 2.8e-45 154.1 0.2 3.5e-45 153.8 0.2 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 EKX48639.1 - 4.5e-08 32.6 0.1 2.3e-05 23.8 0.0 2.6 3 0 0 3 3 3 2 C-C_Bond_Lyase of the TIM-Barrel fold PDZ_6 PF17820.1 EKX48640.1 - 7.3e-10 38.6 0.1 1.3e-09 37.8 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX48640.1 - 5.5e-09 36.2 0.0 1e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX48640.1 - 1.1e-06 28.9 0.0 1.9e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 PDZ domain APG6_N PF17675.1 EKX48640.1 - 0.0037 17.8 0.9 0.0054 17.3 0.9 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region GIT1_C PF12205.8 EKX48640.1 - 0.073 13.2 1.7 0.15 12.2 1.1 1.7 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term YlqD PF11068.8 EKX48640.1 - 1.1 9.7 3.8 2 8.8 3.8 1.3 1 0 0 1 1 1 0 YlqD protein PEHE PF15275.6 EKX48640.1 - 1.6 9.3 6.7 3.3 8.4 6.1 1.7 1 1 0 1 1 1 0 PEHE domain CIA30 PF08547.12 EKX48641.1 - 1.2e-32 113.1 0.0 2.4e-32 112.2 0.0 1.4 2 0 0 2 2 2 1 Complex I intermediate-associated protein 30 (CIA30) RNA_polI_A34 PF08208.11 EKX48642.1 - 5.2e-17 62.6 6.1 5.9e-17 62.4 6.1 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 DUF5130 PF17174.4 EKX48642.1 - 0.14 12.4 0.1 0.35 11.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5130) RCC1 PF00415.18 EKX48643.1 - 1.2e-36 125.0 23.1 5.8e-14 52.5 0.1 6.2 5 2 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX48643.1 - 6.4e-20 70.4 24.9 1.2e-07 31.3 1.5 5.2 4 1 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat Occludin_ELL PF07303.13 EKX48644.1 - 0.029 15.1 5.9 13 6.6 5.0 2.9 2 1 0 2 2 2 0 Occludin homology domain PDZ_2 PF13180.6 EKX48645.1 - 5.9e-10 39.3 2.5 6.7e-08 32.7 0.1 3.9 4 1 0 4 4 4 1 PDZ domain PDZ PF00595.24 EKX48645.1 - 4.4e-07 30.1 0.2 0.0012 19.1 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EKX48645.1 - 7.2e-05 22.5 0.0 0.0013 18.5 0.0 2.5 2 0 0 2 2 2 1 PDZ domain DegS PF05384.11 EKX48645.1 - 0.014 14.9 8.4 0.03 13.8 8.4 1.7 1 0 0 1 1 1 0 Sensor protein DegS Prominin PF05478.11 EKX48645.1 - 0.051 11.5 3.3 0.077 10.9 3.3 1.3 1 0 0 1 1 1 0 Prominin ATG16 PF08614.11 EKX48645.1 - 0.31 11.2 20.0 4.6 7.4 20.0 2.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 EKX48645.1 - 0.37 11.0 16.5 1.3 9.2 5.8 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family NEMO PF11577.8 EKX48646.1 - 0.048 13.7 0.4 0.048 13.7 0.4 2.0 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO SPRY PF00622.28 EKX48647.1 - 2.7e-08 34.0 0.1 3.6e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 SPRY domain fn3 PF00041.21 EKX48648.1 - 0.0003 21.1 0.1 0.00083 19.6 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III domain Tubulin PF00091.25 EKX48650.1 - 4.7e-29 102.0 0.0 3.3e-28 99.3 0.0 2.4 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain MANEC PF07502.14 EKX48650.1 - 0.055 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 MANEC domain Tubulin_2 PF13809.6 EKX48650.1 - 0.099 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Tubulin like PMSR PF01625.21 EKX48651.1 - 9.5e-59 198.0 0.2 1.1e-58 197.7 0.2 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase CooT PF10133.9 EKX48651.1 - 0.066 13.5 0.1 13 6.1 0.1 2.3 2 0 0 2 2 2 0 CO dehydrogenase accessory protein CooT DUF4298 PF14131.6 EKX48651.1 - 0.24 11.4 2.1 0.49 10.4 1.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4298) RWP-RK PF02042.15 EKX48653.1 - 2.6e-10 40.1 1.0 6.2e-10 38.9 1.0 1.7 1 0 0 1 1 1 1 RWP-RK domain TMF_TATA_bd PF12325.8 EKX48653.1 - 0.00025 21.2 7.6 0.093 13.0 6.1 2.3 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 EKX48653.1 - 0.0022 18.6 9.5 0.15 12.6 5.5 2.2 2 0 0 2 2 2 2 Apg6 coiled-coil region Spc24 PF08286.11 EKX48653.1 - 0.0039 17.4 2.0 2.4 8.5 1.9 2.5 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 KASH_CCD PF14662.6 EKX48653.1 - 0.0042 16.9 11.5 0.059 13.2 7.2 2.1 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH SKA2 PF16740.5 EKX48653.1 - 0.0056 16.5 3.0 0.0056 16.5 3.0 2.1 2 0 0 2 2 2 1 Spindle and kinetochore-associated protein 2 HAP1_N PF04849.13 EKX48653.1 - 0.0083 15.4 4.1 0.054 12.7 2.0 2.2 2 0 0 2 2 2 1 HAP1 N-terminal conserved region GAS PF13851.6 EKX48653.1 - 0.0087 15.4 6.6 0.34 10.2 2.4 2.2 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding DUF724 PF05266.14 EKX48653.1 - 0.022 14.6 3.7 1.8 8.4 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 EKX48653.1 - 0.03 14.3 3.0 0.17 11.9 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SHE3 PF17078.5 EKX48653.1 - 0.044 13.5 5.5 1.3 8.7 3.9 2.1 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 CENP-H PF05837.12 EKX48653.1 - 0.069 13.6 7.5 1.2 9.6 5.5 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF3450 PF11932.8 EKX48653.1 - 0.083 12.2 6.5 0.42 9.9 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DivIC PF04977.15 EKX48653.1 - 0.13 12.0 9.7 1.4 8.7 0.2 2.9 2 1 1 3 3 3 0 Septum formation initiator YabA PF06156.13 EKX48653.1 - 0.2 12.3 2.8 3 8.5 2.0 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Uso1_p115_C PF04871.13 EKX48653.1 - 0.25 11.7 8.9 7.8 6.9 5.0 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region WD40_alt PF14077.6 EKX48653.1 - 0.3 11.0 1.6 0.42 10.5 0.2 2.0 2 0 0 2 2 1 0 Alternative WD40 repeat motif DUF5082 PF16888.5 EKX48653.1 - 0.4 11.0 7.1 4.1 7.7 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) bZIP_1 PF00170.21 EKX48653.1 - 0.46 10.6 13.7 0.64 10.2 4.9 3.0 2 2 1 3 3 3 0 bZIP transcription factor DUF465 PF04325.13 EKX48653.1 - 0.68 10.0 4.3 5.5 7.1 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF465) FlxA PF14282.6 EKX48653.1 - 0.73 9.9 12.5 2 8.4 3.1 3.3 2 1 1 3 3 3 0 FlxA-like protein PRKG1_interact PF15898.5 EKX48653.1 - 0.73 10.8 8.3 3.1 8.8 4.4 2.4 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain ADIP PF11559.8 EKX48653.1 - 0.98 9.5 10.4 5.1 7.2 5.6 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding BLOC1_2 PF10046.9 EKX48653.1 - 1.1 9.6 7.8 16 5.8 5.8 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UPF0242 PF06785.11 EKX48653.1 - 1.1 9.3 10.4 6.2 6.9 10.3 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CCDC92 PF14916.6 EKX48653.1 - 2.1 8.2 9.0 5 7.0 0.6 2.9 3 0 0 3 3 3 0 Coiled-coil domain of unknown function Spc7 PF08317.11 EKX48653.1 - 3.1 6.6 8.3 4 6.2 4.2 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Swi5 PF07061.11 EKX48653.1 - 3.6 7.7 8.1 9.4 6.4 0.1 3.1 3 1 0 3 3 2 0 Swi5 DUF3552 PF12072.8 EKX48653.1 - 6 6.2 10.8 1 8.8 4.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) ZapB PF06005.12 EKX48653.1 - 6.4 7.3 17.3 11 6.6 0.5 2.4 2 0 0 2 2 2 0 Cell division protein ZapB GIT_CC PF16559.5 EKX48653.1 - 8.3 6.4 15.4 0.93 9.4 0.8 4.0 3 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Med21 PF11221.8 EKX48653.1 - 8.5 6.6 10.5 8.3 6.7 4.8 2.9 2 1 1 3 3 3 0 Subunit 21 of Mediator complex Telomerase_RBD PF12009.8 EKX48660.1 - 3.5e-35 121.0 1.3 7.8e-35 119.9 1.3 1.6 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 EKX48660.1 - 0.00062 19.3 0.0 0.0061 16.1 0.0 2.5 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) IlvC PF01450.19 EKX48661.1 - 2e-42 144.9 0.2 6.2e-32 110.9 0.0 2.3 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.12 EKX48661.1 - 7.8e-36 123.1 0.1 1.4e-35 122.3 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain PTPLA PF04387.14 EKX48663.1 - 1e-39 135.9 2.9 1.7e-39 135.2 2.9 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA IBR PF01485.21 EKX48664.1 - 8.9 6.6 8.9 50 4.2 0.6 3.4 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain 2-oxoacid_dh PF00198.23 EKX48665.1 - 1.2e-64 218.0 0.1 1.6e-64 217.6 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 EKX48665.1 - 1.1e-28 99.3 1.6 3.7e-14 52.8 0.3 2.8 2 0 0 2 2 2 2 e3 binding domain Biotin_lipoyl PF00364.22 EKX48665.1 - 2.6e-19 68.8 2.8 5.3e-19 67.8 2.8 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EKX48665.1 - 0.0036 17.1 0.4 0.087 12.7 0.1 2.6 1 1 1 2 2 2 1 Biotin-lipoyl like DciA PF05258.12 EKX48665.1 - 0.12 12.7 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 Dna[CI] antecedent, DciA Ribosomal_L3 PF00297.22 EKX48666.1 - 1.4e-175 583.7 11.7 1.5e-175 583.5 11.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Kri1 PF05178.12 EKX48667.1 - 0.027 15.0 1.9 0.029 14.9 1.9 1.1 1 0 0 1 1 1 0 KRI1-like family PH PF00169.29 EKX48668.1 - 0.045 14.3 0.0 0.091 13.3 0.0 1.5 1 0 0 1 1 1 0 PH domain zf-RanBP PF00641.18 EKX48669.1 - 2.9e-15 55.3 28.8 4.1e-06 26.0 1.3 4.6 4 0 0 4 4 4 4 Zn-finger in Ran binding protein and others DZR PF12773.7 EKX48669.1 - 2.5e-07 30.6 22.1 0.0013 18.7 4.9 3.6 2 1 1 3 3 3 3 Double zinc ribbon zf-C3HC4_3 PF13920.6 EKX48669.1 - 3.1e-05 23.7 24.6 0.18 11.7 0.7 4.2 4 0 0 4 4 4 4 Zinc finger, C3HC4 type (RING finger) Rubredoxin PF00301.20 EKX48669.1 - 0.017 15.1 28.6 0.25 11.4 0.4 5.4 5 1 0 5 5 5 0 Rubredoxin zf-ACC PF17848.1 EKX48669.1 - 0.031 14.4 11.8 3.4 7.8 0.1 4.8 4 1 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain PHD PF00628.29 EKX48669.1 - 0.066 13.1 13.3 4.1 7.4 0.1 5.4 4 1 0 4 4 4 0 PHD-finger zinc-ribbon_6 PF10005.9 EKX48669.1 - 0.068 13.9 21.4 5 7.9 0.3 4.2 4 0 0 4 4 4 0 zinc-ribbon domain zf-MIZ PF02891.20 EKX48669.1 - 0.38 10.5 13.4 11 5.9 0.5 4.4 4 0 0 4 4 4 0 MIZ/SP-RING zinc finger zf-4CXXC_R1 PF10497.9 EKX48669.1 - 1 9.6 23.6 5.3 7.3 1.3 4.3 3 1 1 4 4 4 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zinc_ribbon_11 PF11682.8 EKX48669.1 - 1.2 9.2 7.4 11 6.1 0.2 3.8 4 0 0 4 4 4 0 Probable zinc-ribbon Sgf11 PF08209.11 EKX48669.1 - 3.3 7.3 8.7 24 4.6 0.0 4.4 4 0 0 4 4 4 0 Sgf11 (transcriptional regulation protein) TackOD1 PF18551.1 EKX48669.1 - 7 6.3 23.8 4.5 6.9 5.2 4.0 3 1 1 4 4 4 0 Thaumarchaeal output domain 1 PhnA_Zn_Ribbon PF08274.12 EKX48669.1 - 7.7 6.6 10.5 17 5.5 0.2 4.5 5 0 0 5 5 5 0 PhnA Zinc-Ribbon E1-E2_ATPase PF00122.20 EKX48671.1 - 3.3e-23 82.1 0.1 1.2e-22 80.3 0.1 2.0 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EKX48671.1 - 2.7e-15 57.2 4.2 6.1e-07 29.9 0.0 3.8 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EKX48671.1 - 0.00071 19.6 0.0 0.0044 17.1 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) CEP63 PF17045.5 EKX48671.1 - 0.036 14.0 8.9 0.059 13.3 8.9 1.2 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa Cation_ATPase_N PF00690.26 EKX48671.1 - 0.14 11.9 0.0 0.45 10.2 0.0 1.9 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EKX48671.1 - 0.16 11.6 3.2 0.66 9.7 0.0 2.8 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Glyco_transf_9 PF01075.17 EKX48671.1 - 0.83 8.9 5.8 2.7 7.2 5.8 1.9 1 1 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) CLZ PF16526.5 EKX48671.1 - 7.9 6.9 10.3 2.7 8.4 7.2 1.8 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Mpv17_PMP22 PF04117.12 EKX48672.1 - 5.1e-21 74.7 2.5 1.2e-20 73.5 2.5 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family LysM PF01476.20 EKX48673.1 - 0.0064 16.5 3.4 0.52 10.4 0.0 3.3 3 0 0 3 3 3 2 LysM domain Zn_clus PF00172.18 EKX48674.1 - 3.8e-05 23.7 7.8 8.5e-05 22.6 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 EKX48675.1 - 3.6e-05 23.8 7.8 8.2e-05 22.7 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RING_2 PF13639.6 EKX48676.1 - 4.4e-13 49.3 8.6 4.8e-13 49.2 8.6 1.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EKX48676.1 - 4.4e-10 39.1 0.9 4.4e-10 39.1 0.9 2.6 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EKX48676.1 - 1.5e-07 31.2 8.6 1.8e-07 30.8 8.6 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX48676.1 - 3.9e-07 29.8 7.3 4.8e-07 29.5 7.3 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX48676.1 - 4.7e-07 29.6 6.1 5.4e-07 29.5 6.1 1.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EKX48676.1 - 2.3e-06 27.5 3.8 2.5e-06 27.4 1.3 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EKX48676.1 - 4.4e-06 26.5 6.6 5.2e-06 26.2 6.6 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX48676.1 - 7e-06 26.2 12.2 3.6e-05 24.0 12.2 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EKX48676.1 - 5e-05 23.1 6.7 7.1e-05 22.6 6.7 1.3 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EKX48676.1 - 0.00078 19.0 9.8 0.0012 18.5 9.8 1.4 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 EKX48676.1 - 0.0081 16.1 3.5 0.0081 16.1 3.5 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 zf-ANAPC11 PF12861.7 EKX48676.1 - 0.066 13.3 7.3 0.2 11.7 7.3 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_5 PF17121.5 EKX48676.1 - 0.28 11.1 6.6 4.2 7.3 0.4 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EKX48676.1 - 0.4 10.9 11.0 8.7 6.6 11.0 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zinc_ribbon_16 PF17034.5 EKX48676.1 - 0.85 9.8 9.9 0.2 11.9 5.4 1.8 1 1 1 2 2 2 0 Zinc-ribbon like family zf-C3H2C3 PF17122.5 EKX48676.1 - 1.6 8.9 14.1 7.9 6.6 14.1 2.4 1 1 0 1 1 1 0 Zinc-finger Cupin_8 PF13621.6 EKX48677.1 - 2.3e-14 53.8 0.0 2e-13 50.7 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EKX48677.1 - 6.4e-05 23.4 0.0 0.00014 22.3 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase PRELI PF04707.14 EKX48678.1 - 7.9e-09 35.5 0.0 1.3e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 PRELI-like family C2 PF00168.30 EKX48679.1 - 8e-22 77.5 0.2 2.1e-19 69.7 0.1 2.7 2 0 0 2 2 2 2 C2 domain Spt20 PF12090.8 EKX48680.1 - 3.8e-15 56.2 7.3 3.5e-07 30.1 0.0 3.2 2 1 1 3 3 3 2 Spt20 family SEP PF08059.13 EKX48680.1 - 0.025 15.2 0.0 0.065 13.8 0.0 1.7 1 0 0 1 1 1 0 SEP domain Ribosomal_L7Ae PF01248.26 EKX48682.1 - 1e-06 28.4 0.1 1.5e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SET PF00856.28 EKX48683.1 - 5.9e-06 26.8 0.0 9.3e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 SET domain Aldedh PF00171.22 EKX48684.1 - 2.5e-89 299.9 0.0 3.3e-89 299.5 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CTU2 PF10288.9 EKX48687.1 - 0.36 11.1 2.8 0.52 10.6 2.8 1.4 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 HAD_2 PF13419.6 EKX48688.1 - 0.041 14.0 0.0 0.77 9.8 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase LCIB_C_CA PF18599.1 EKX48690.1 - 7.5e-48 162.7 0.0 8.3e-48 162.6 0.0 1.0 1 0 0 1 1 1 1 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Ribosomal_S28e PF01200.18 EKX48691.1 - 1.9e-31 107.8 1.6 2.1e-31 107.7 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Sec10 PF07393.11 EKX48692.1 - 1.6e-63 215.3 14.1 3.3e-62 211.0 14.1 2.0 1 1 0 1 1 1 1 Exocyst complex component Sec10 Z1 PF10593.9 EKX48692.1 - 0.36 10.3 0.0 0.36 10.3 0.0 2.6 3 2 2 5 5 5 0 Z1 domain GlutR_dimer PF00745.20 EKX48692.1 - 2.7 8.5 6.6 2.5 8.6 0.1 3.9 3 1 1 4 4 4 0 Glutamyl-tRNAGlu reductase, dimerisation domain LMBR1 PF04791.16 EKX48693.1 - 0.00038 19.5 13.1 0.00047 19.2 13.1 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein PDZ_6 PF17820.1 EKX48694.1 - 7.2e-13 48.2 1.2 1.2e-12 47.5 0.6 1.7 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX48694.1 - 2.3e-12 47.1 1.2 4.1e-12 46.3 1.2 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX48694.1 - 6.1e-12 45.7 0.4 1.3e-11 44.7 0.4 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX48694.1 - 0.0064 16.4 0.1 0.011 15.6 0.1 1.5 1 1 0 1 1 1 1 Tricorn protease PDZ domain Lipoprotein_20 PF13942.6 EKX48694.1 - 0.027 14.4 1.4 0.038 13.9 1.4 1.1 1 0 0 1 1 1 0 YfhG lipoprotein Rhamno_transf PF11316.8 EKX48694.1 - 0.075 12.4 0.8 0.11 11.9 0.8 1.1 1 0 0 1 1 1 0 Putative rhamnosyl transferase TMF_TATA_bd PF12325.8 EKX48694.1 - 0.09 13.0 6.9 0.13 12.4 6.9 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding bZIP_2 PF07716.15 EKX48694.1 - 0.52 10.4 6.3 0.86 9.7 6.3 1.3 1 0 0 1 1 1 0 Basic region leucine zipper zf-met2 PF12907.7 EKX48695.1 - 2.2e-13 50.1 3.9 3.7e-13 49.4 3.9 1.4 1 0 0 1 1 1 1 Zinc-binding zf-C2H2_4 PF13894.6 EKX48695.1 - 0.085 13.7 0.6 0.19 12.7 0.6 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger 4F5 PF04419.14 EKX48695.1 - 1.8 9.5 7.5 4.1 8.4 7.5 1.6 1 0 0 1 1 1 0 4F5 protein family SWIB PF02201.18 EKX48696.1 - 1.8e-15 56.6 0.0 1e-14 54.2 0.0 2.2 3 0 0 3 3 3 1 SWIB/MDM2 domain PDZ PF00595.24 EKX48697.1 - 1.6e-08 34.8 0.0 4.5e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX48697.1 - 4.2e-08 32.9 0.2 9.6e-08 31.8 0.2 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX48697.1 - 1.2e-05 25.6 0.7 3.2e-05 24.2 0.1 2.1 2 1 0 2 2 2 1 PDZ domain z-alpha PF02295.17 EKX48697.1 - 0.051 13.6 0.5 0.19 11.8 0.5 1.9 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain V-set_2 PF15910.5 EKX48697.1 - 0.15 12.1 0.7 0.33 11.1 0.7 1.5 1 0 0 1 1 1 0 ICOS V-set domain Mito_carr PF00153.27 EKX48698.1 - 4.9e-33 112.9 0.1 1.7e-08 34.2 0.0 4.5 4 0 0 4 4 4 4 Mitochondrial carrier protein UPF0181 PF03701.14 EKX48698.1 - 0.002 17.7 0.0 0.0076 15.9 0.0 2.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0181) DUF4407 PF14362.6 EKX48698.1 - 0.14 11.5 3.7 0.24 10.7 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF87 PF01935.17 EKX48698.1 - 0.16 12.0 2.6 0.28 11.3 2.6 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain Radial_spoke PF04712.12 EKX48698.1 - 0.17 10.8 3.2 0.27 10.1 3.2 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein GSIII_N PF12437.8 EKX48699.1 - 4.9e-44 149.8 1.3 1.4e-43 148.3 0.1 2.3 2 1 1 3 3 3 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 EKX48699.1 - 2e-33 114.7 0.1 3.5e-33 114.0 0.1 1.4 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 EKX48699.1 - 1.6e-22 80.0 0.0 1.1e-21 77.2 0.0 2.2 3 0 0 3 3 3 1 Glutamine synthetase, catalytic domain Rota_NSP3 PF01665.16 EKX48699.1 - 0.23 10.5 0.6 0.36 9.9 0.6 1.2 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 DUF4159 PF13709.6 EKX48700.1 - 0.077 12.4 0.0 0.66 9.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4159) MRG PF05712.13 EKX48704.1 - 9.4e-20 70.8 0.8 6.9e-14 51.6 0.0 3.4 3 2 1 4 4 4 2 MRG HMG_box PF00505.19 EKX48704.1 - 1.6e-05 25.2 2.7 1.6e-05 25.2 2.7 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box F-box-like PF12937.7 EKX48706.1 - 3.4e-05 23.6 0.2 6.7e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EKX48706.1 - 0.0038 17.1 0.1 0.0074 16.1 0.1 1.5 1 0 0 1 1 1 1 F-box domain GSIII_N PF12437.8 EKX48707.1 - 6.9e-50 168.8 0.2 3.9e-49 166.4 0.0 2.3 2 1 1 3 3 3 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 EKX48707.1 - 1.9e-33 114.8 0.1 3.2e-33 114.1 0.1 1.4 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 EKX48707.1 - 1.5e-22 80.1 0.0 1.1e-21 77.3 0.0 2.2 3 0 0 3 3 3 1 Glutamine synthetase, catalytic domain Rota_NSP3 PF01665.16 EKX48707.1 - 0.22 10.6 0.6 0.35 10.0 0.6 1.3 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 TPR_19 PF14559.6 EKX48709.1 - 5.8e-05 23.5 3.1 0.011 16.2 0.3 4.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX48709.1 - 0.0055 17.4 8.4 0.36 11.8 0.0 5.3 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX48709.1 - 0.11 12.7 0.0 1 9.6 0.0 2.8 1 0 0 1 1 1 0 Tetratricopeptide repeat QRPTase_C PF01729.19 EKX48710.1 - 1.1e-21 77.4 0.1 1.6e-21 76.8 0.1 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EKX48710.1 - 1.2e-20 73.3 0.0 2e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain zf-met2 PF12907.7 EKX48711.1 - 0.35 11.0 4.1 1 9.6 4.1 1.8 1 1 0 1 1 1 0 Zinc-binding EF-hand_5 PF13202.6 EKX48712.1 - 0.00054 19.3 2.3 0.00054 19.3 2.3 1.9 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EKX48712.1 - 0.00099 19.5 5.1 0.008 16.6 0.5 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX48712.1 - 0.0013 18.5 1.9 0.0029 17.4 0.6 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EKX48712.1 - 0.0046 16.4 4.4 0.0046 16.4 2.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EKX48712.1 - 0.025 14.4 2.4 0.081 12.8 1.3 2.4 1 1 1 2 2 2 0 EF-hand domain pair HMD PF03201.16 EKX48712.1 - 0.028 14.6 1.5 0.098 12.9 0.4 2.3 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase TipAS PF07739.13 EKX48712.1 - 0.15 12.6 0.9 0.71 10.4 0.1 2.3 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain LIN52 PF10044.9 EKX48712.1 - 0.16 12.7 1.7 0.41 11.4 0.6 2.2 2 0 0 2 2 2 0 Retinal tissue protein Peptidase_S49 PF01343.18 EKX48712.1 - 0.17 11.8 1.3 0.7 9.8 0.1 2.2 2 1 1 3 3 3 0 Peptidase family S49 Herpes_pp38 PF04846.13 EKX48713.1 - 0.075 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein Ephrin_rec_like PF07699.13 EKX48714.1 - 2.3e-13 49.7 116.6 8.8e-06 25.4 9.5 10.5 7 3 3 10 10 10 7 Putative ephrin-receptor like RTC4 PF14474.6 EKX48714.1 - 0.00061 20.0 8.4 16 5.7 0.1 5.4 5 0 0 5 5 5 2 RTC4-like domain Opy2 PF09463.10 EKX48714.1 - 0.029 14.7 4.2 0.029 14.7 4.2 10.4 10 5 4 14 14 14 0 Opy2 protein zf-ACC PF17848.1 EKX48714.1 - 0.071 13.2 5.4 1.8 8.7 1.6 3.6 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain DUF4501 PF14946.6 EKX48714.1 - 3.3 7.8 59.8 0.71 9.9 2.9 6.2 1 1 3 6 6 6 0 Domain of unknown function (DUF4501) DUF515 PF04415.12 EKX48717.1 - 0.48 8.7 6.9 0.17 10.2 4.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF515) SR-25 PF10500.9 EKX48717.1 - 0.83 9.2 12.5 1.2 8.6 12.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.11 EKX48717.1 - 1.7 6.9 5.5 2 6.6 5.5 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PCRF PF03462.18 EKX48718.1 - 6.7e-49 166.4 0.0 1.2e-48 165.5 0.0 1.4 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 EKX48718.1 - 1.5e-35 121.6 0.3 3.6e-35 120.4 0.3 1.6 1 0 0 1 1 1 1 RF-1 domain CorA PF01544.18 EKX48718.1 - 1.3 8.3 3.8 0.25 10.6 0.3 1.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein PP2C PF00481.21 EKX48721.1 - 5.5e-47 160.6 0.0 7.7e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EKX48721.1 - 7.7e-05 22.4 0.0 0.00013 21.7 0.0 1.3 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 EKX48722.1 - 1.9e-47 162.0 0.0 2.7e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EKX48722.1 - 3e-05 23.8 0.0 5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 EKX48723.1 - 4.2e-11 43.0 0.0 4.7e-11 42.8 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C DUF5018 PF16410.5 EKX48723.1 - 0.13 11.0 0.0 0.29 9.8 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5018) GILT PF03227.16 EKX48726.1 - 4.5e-22 78.3 3.0 5.5e-22 78.0 1.4 1.8 1 1 1 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Thioredoxin_4 PF13462.6 EKX48726.1 - 0.039 14.1 0.2 0.27 11.4 0.0 2.3 3 0 0 3 3 3 0 Thioredoxin Bcl-2 PF00452.19 EKX48727.1 - 0.079 13.7 0.1 2 9.1 0.0 2.5 2 0 0 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family VasI PF11319.8 EKX48727.1 - 0.31 10.7 4.1 4.5 6.9 0.1 2.4 1 1 1 2 2 2 0 Type VI secretion system VasI, EvfG, VC_A0118 DUF1090 PF06476.12 EKX48727.1 - 0.39 10.9 7.5 4.6 7.4 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1090) SHIPPO-rpt PF07004.12 EKX48728.1 - 6e-12 45.9 36.2 0.17 12.9 0.2 8.9 9 0 0 9 9 9 6 Sperm-tail PG-rich repeat Pro_CA PF00484.19 EKX48729.1 - 3e-38 131.6 2.5 4.9e-38 130.9 0.0 2.4 3 0 0 3 3 3 1 Carbonic anhydrase V_ATPase_I PF01496.19 EKX48729.1 - 0.89 7.4 3.5 1.2 7.0 3.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4366 PF14283.6 EKX48729.1 - 6.4 6.8 6.7 12 5.9 6.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) PP2C PF00481.21 EKX48730.1 - 5.9e-46 157.2 0.0 6.8e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EKX48730.1 - 0.00013 21.7 0.0 0.0002 21.0 0.0 1.3 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 EKX48731.1 - 1.1e-45 156.4 0.0 1.5e-45 155.9 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EKX48731.1 - 6.3e-05 22.7 0.0 0.0001 22.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Toxin_34 PF08396.10 EKX48731.1 - 0.056 14.2 0.6 0.12 13.1 0.6 1.5 1 0 0 1 1 1 0 Spider toxin omega agatoxin/Tx1 family UCH PF00443.29 EKX48732.1 - 2.2e-20 73.2 0.0 2.8e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EKX48732.1 - 1.5e-06 28.0 0.4 4.6e-06 26.5 0.4 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF2069 PF09842.9 EKX48732.1 - 0.098 12.9 0.1 0.15 12.2 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2069) C1_2 PF03107.16 EKX48732.1 - 0.33 11.3 3.2 19 5.6 0.0 3.2 3 0 0 3 3 3 0 C1 domain DAGAT PF03982.13 EKX48735.1 - 3.6e-72 242.8 0.0 4e-72 242.6 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Prefoldin_2 PF01920.20 EKX48738.1 - 8.5e-17 61.0 5.1 1e-16 60.8 5.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit DivIC PF04977.15 EKX48738.1 - 0.051 13.3 1.5 1.1 9.1 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator Prefoldin PF02996.17 EKX48738.1 - 0.056 13.3 4.2 0.15 12.0 0.6 2.1 1 1 1 2 2 2 0 Prefoldin subunit FlaC_arch PF05377.11 EKX48738.1 - 0.062 13.7 3.9 0.83 10.1 0.3 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4164 PF13747.6 EKX48738.1 - 0.1 12.9 2.7 7 7.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF4472 PF14739.6 EKX48738.1 - 0.17 12.7 6.8 0.28 11.9 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) DUF4201 PF13870.6 EKX48738.1 - 0.26 11.0 7.1 0.69 9.6 7.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) DUF4140 PF13600.6 EKX48738.1 - 0.38 11.2 3.7 5.2 7.6 0.2 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Cnn_1N PF07989.11 EKX48738.1 - 0.41 10.8 5.8 1.5 9.0 0.5 2.2 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Atx10homo_assoc PF09759.9 EKX48739.1 - 0.026 14.5 7.5 0.094 12.7 0.2 3.9 3 1 3 6 6 6 0 Spinocerebellar ataxia type 10 protein domain baeRF_family3 PF18845.1 EKX48739.1 - 0.21 11.8 7.7 0.15 12.3 3.2 2.7 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 3 UDPG_MGDP_dh_C PF03720.15 EKX48739.1 - 0.35 11.3 1.7 2.6 8.5 0.1 2.9 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Arm PF00514.23 EKX48739.1 - 0.43 10.7 7.5 33 4.7 0.1 6.1 7 1 1 8 8 8 0 Armadillo/beta-catenin-like repeat TPR_16 PF13432.6 EKX48740.1 - 9.5e-05 23.0 0.7 0.00017 22.1 0.1 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX48740.1 - 0.00062 19.4 0.6 0.0012 18.5 0.6 1.4 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.17 EKX48740.1 - 0.0013 18.7 0.0 0.0037 17.2 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX48740.1 - 0.0066 16.7 0.8 0.013 15.9 0.1 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX48740.1 - 0.016 15.0 0.0 0.039 13.8 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX48740.1 - 0.14 12.4 0.2 0.75 10.2 0.0 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_8 PF13855.6 EKX48741.1 - 2.6e-17 62.3 11.8 4.2e-08 32.8 1.1 3.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EKX48741.1 - 7.3e-13 48.5 3.3 0.00014 22.1 0.3 3.6 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX48741.1 - 7.3e-09 35.0 5.6 1.6 9.6 0.0 5.7 5 1 0 5 5 5 4 Leucine Rich Repeat LRR_6 PF13516.6 EKX48741.1 - 2.4e-05 24.0 8.9 0.14 12.2 0.2 4.8 5 0 0 5 5 5 3 Leucine Rich repeat AMPK1_CBM PF16561.5 EKX48743.1 - 2e-15 56.8 0.2 2e-15 56.8 0.2 3.0 2 1 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase Nucleoporin_FG PF13634.6 EKX48745.1 - 4.9e-17 62.6 153.8 2.9e-10 40.9 27.0 7.2 1 1 5 6 6 6 5 Nucleoporin FG repeat region Hydrolase_4 PF12146.8 EKX48746.1 - 0.07 12.4 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FtsX PF02687.21 EKX48746.1 - 3.7 8.1 6.9 4.6 7.8 0.1 2.7 2 0 0 2 2 2 0 FtsX-like permease family PEMT PF04191.13 EKX48747.1 - 3.5e-08 33.8 1.1 3.5e-08 33.8 1.1 2.4 3 1 0 3 3 3 1 Phospholipid methyltransferase DUF1499 PF07386.11 EKX48749.1 - 1.3e-11 45.0 0.0 2e-11 44.5 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1499) Rad51 PF08423.11 EKX48750.1 - 0.00027 20.3 0.3 0.00077 18.8 0.3 1.8 1 1 0 1 1 1 1 Rad51 WD40 PF00400.32 EKX48752.1 - 0.00019 22.2 0.1 50 5.0 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF2205 PF10224.9 EKX48753.1 - 0.0058 16.6 1.3 0.0058 16.6 1.3 4.4 3 2 1 4 4 4 1 Short coiled-coil protein Fzo_mitofusin PF04799.13 EKX48753.1 - 0.0089 15.6 3.7 0.0089 15.6 3.7 3.5 1 1 1 3 3 3 1 fzo-like conserved region ATG16 PF08614.11 EKX48753.1 - 0.014 15.6 15.7 0.014 15.6 15.7 3.2 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) DUF948 PF06103.11 EKX48753.1 - 0.19 12.0 14.7 0.11 12.8 3.0 3.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF2935 PF11155.8 EKX48753.1 - 0.3 11.4 15.3 0.7 10.2 2.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF2935) LMBR1 PF04791.16 EKX48753.1 - 2.7 6.8 17.4 2.3 7.0 10.5 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein Filament PF00038.21 EKX48753.1 - 2.8 7.5 45.0 1.8 8.0 31.5 2.6 1 1 0 1 1 1 0 Intermediate filament protein ANAPC2 PF08672.11 EKX48753.1 - 4.2 8.0 5.6 18 6.0 0.1 3.4 3 0 0 3 3 3 0 Anaphase promoting complex (APC) subunit 2 DUF3584 PF12128.8 EKX48753.1 - 4.7 4.6 35.1 6.4 4.1 35.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 EKX48753.1 - 8.5 6.4 11.4 1.8 8.6 2.6 2.6 2 2 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LRR_6 PF13516.6 EKX48755.1 - 5.6e-24 82.1 40.5 0.00014 21.6 0.1 9.8 10 0 0 10 10 10 8 Leucine Rich repeat LRR_1 PF00560.33 EKX48755.1 - 5.5e-06 26.2 18.8 3.9 8.4 0.1 7.8 7 1 0 7 7 7 3 Leucine Rich Repeat LRR_4 PF12799.7 EKX48755.1 - 5.1e-05 23.6 37.4 0.026 15.0 1.9 6.6 3 3 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX48755.1 - 0.0018 18.0 32.2 0.43 10.4 5.4 7.3 4 3 1 5 5 5 4 Leucine rich repeat LRR_2 PF07723.13 EKX48755.1 - 0.035 14.8 9.1 11 6.8 0.0 5.9 7 0 0 7 7 7 0 Leucine Rich Repeat UPF0262 PF06793.12 EKX48755.1 - 0.036 14.2 0.0 19 5.3 0.0 3.1 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0262) DUF2779 PF11074.8 EKX48756.1 - 3.1e-26 92.3 0.7 1.8e-23 83.4 0.2 2.4 2 0 0 2 2 2 2 Domain of unknown function(DUF2779) Cas_Cas4 PF01930.17 EKX48756.1 - 0.001 19.2 0.9 0.0036 17.4 0.5 2.1 1 1 0 1 1 1 1 Domain of unknown function DUF83 LpxB PF02684.15 EKX48757.1 - 0.012 14.4 0.8 0.016 14.0 0.8 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase PDDEXK_7 PF04411.12 EKX48757.1 - 0.057 13.4 1.6 0.078 13.0 1.6 1.4 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily SRCR PF00530.18 EKX48757.1 - 0.12 12.9 0.6 0.2 12.2 0.4 1.4 1 1 0 1 1 1 0 Scavenger receptor cysteine-rich domain Borrelia_P83 PF05262.11 EKX48757.1 - 1.6 7.1 9.6 1.8 7.0 9.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein PGA2 PF07543.12 EKX48757.1 - 7.3 6.6 13.6 0.29 11.1 6.2 2.0 1 1 1 2 2 2 0 Protein trafficking PGA2 DUF2207 PF09972.9 EKX48758.1 - 0.053 12.3 3.4 0.065 12.0 3.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Caveolin PF01146.17 EKX48758.1 - 0.78 9.7 7.2 1.5 8.7 7.2 1.5 1 0 0 1 1 1 0 Caveolin Adeno_E3B PF03376.14 EKX48758.1 - 2.4 8.5 6.3 2.5 8.4 1.5 2.2 1 1 1 2 2 2 0 Adenovirus E3B protein Proteasome PF00227.26 EKX48759.1 - 2.4e-28 98.9 0.0 2.8e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit AAA_23 PF13476.6 EKX48760.1 - 2.2e-13 51.2 0.2 2.9e-13 50.8 0.2 1.3 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 EKX48760.1 - 4.5e-12 45.9 0.0 5.3e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EKX48760.1 - 2.9e-07 30.5 3.2 2.4e-06 27.5 3.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EKX48760.1 - 0.00038 20.1 0.0 0.00071 19.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EKX48760.1 - 0.0017 18.2 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ParA PF10609.9 EKX48760.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase AAA_16 PF13191.6 EKX48760.1 - 0.027 14.9 0.0 0.038 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_13 PF13166.6 EKX48760.1 - 0.027 13.1 0.8 0.21 10.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 EKX48760.1 - 0.1 12.7 0.4 0.27 11.3 0.1 1.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_27 PF13514.6 EKX48760.1 - 0.1 12.2 0.1 0.2 11.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EKX48760.1 - 0.12 11.6 0.3 0.39 10.0 0.3 1.9 1 1 0 1 1 1 0 Zeta toxin NACHT PF05729.12 EKX48760.1 - 0.14 12.1 0.1 0.38 10.6 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 EKX48760.1 - 0.18 11.4 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 EKX48761.1 - 3e-63 213.7 0.0 3.4e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX48761.1 - 9.8e-39 133.2 0.0 1.2e-38 132.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX48761.1 - 1.1e-07 31.5 0.0 0.0011 18.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like WD40 PF00400.32 EKX48762.1 - 1.4e-09 38.4 11.9 4.6e-05 24.1 0.0 5.3 4 1 1 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX48762.1 - 5.1e-07 29.9 0.0 0.00013 22.2 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain S1 PF00575.23 EKX48763.1 - 4.5e-41 139.0 10.9 2.7e-20 72.5 1.6 2.7 3 0 0 3 3 3 2 S1 RNA binding domain S1_2 PF13509.6 EKX48763.1 - 0.0039 17.2 1.2 1.6 8.8 0.1 3.1 2 1 0 2 2 2 2 S1 domain TRAM_2 PF18693.1 EKX48763.1 - 0.062 13.5 4.3 5.2 7.3 0.3 2.6 2 0 0 2 2 2 0 TRAM domain Asp_Arg_Hydrox PF05118.15 EKX48764.1 - 3.9e-20 72.3 0.3 5.3e-10 39.3 0.1 2.4 1 1 1 2 2 2 2 Aspartyl/Asparaginyl beta-hydroxylase DAGAT PF03982.13 EKX48765.1 - 1.4e-30 106.3 0.0 1.8e-30 105.9 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase AAA_23 PF13476.6 EKX48766.1 - 5.7e-14 53.1 0.1 7.9e-14 52.6 0.1 1.2 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 EKX48766.1 - 1.1e-11 44.6 0.0 1.3e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EKX48766.1 - 2.3e-07 30.9 2.1 9.4e-07 28.9 0.2 1.9 1 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EKX48766.1 - 0.00029 20.5 0.0 0.00053 19.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EKX48766.1 - 0.0011 18.8 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_13 PF13166.6 EKX48766.1 - 0.043 12.5 1.0 0.28 9.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EKX48766.1 - 0.049 14.0 0.0 0.068 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain DUF2813 PF11398.8 EKX48766.1 - 0.054 12.7 0.1 0.12 11.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) ParA PF10609.9 EKX48766.1 - 0.06 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase AAA_27 PF13514.6 EKX48766.1 - 0.068 12.8 0.0 0.13 11.8 0.0 1.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EKX48766.1 - 0.072 12.4 0.0 0.85 8.9 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 EKX48767.1 - 5.1e-13 50.0 0.1 7.3e-13 49.5 0.1 1.3 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 EKX48767.1 - 7.5e-11 41.9 0.0 8.8e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EKX48767.1 - 5.7e-07 29.6 3.0 1.3e-06 28.4 0.3 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EKX48767.1 - 0.00095 18.9 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EKX48767.1 - 0.0049 16.7 0.0 0.0062 16.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_13 PF13166.6 EKX48767.1 - 0.052 12.2 1.2 0.29 9.7 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EKX48767.1 - 0.061 13.7 0.0 0.084 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_27 PF13514.6 EKX48767.1 - 0.086 12.4 0.0 0.16 11.5 0.0 1.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EKX48767.1 - 0.095 12.0 0.0 1.2 8.4 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin HEAT_UF PF18817.1 EKX48768.1 - 0.63 10.4 2.7 0.56 10.5 0.5 2.1 2 0 0 2 2 2 0 Repeat of uncharacterized protein PH0542 Pkinase PF00069.25 EKX48771.1 - 1e-19 71.0 0.0 1.1e-19 70.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX48771.1 - 2.8e-13 49.7 0.0 3.1e-13 49.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX48771.1 - 0.00054 18.8 0.0 0.00061 18.7 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EKX48771.1 - 0.032 13.8 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 EKX48771.1 - 0.034 13.5 0.0 0.041 13.2 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX48771.1 - 0.098 12.6 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EKX48771.1 - 0.2 11.0 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 EKX48771.1 - 0.22 10.4 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain DUF4116 PF13475.6 EKX48772.1 - 5.1e-29 99.8 0.0 8.4e-09 35.0 0.0 4.0 1 1 2 4 4 4 4 Domain of unknown function (DUF4116) Cas9_Topo PF17894.1 EKX48772.1 - 0.0061 16.6 0.2 4.7 7.3 0.0 2.4 2 0 0 2 2 2 2 Topo homolgy domain in CRISPR-associated endonuclease Cas9 Aldedh PF00171.22 EKX48772.1 - 0.035 12.6 0.4 2.5 6.5 0.1 2.0 1 1 1 2 2 2 0 Aldehyde dehydrogenase family cIII PF08134.11 EKX48772.1 - 0.043 13.6 0.8 10 5.9 0.1 2.4 2 0 0 2 2 2 0 cIII protein family SurA_N PF09312.11 EKX48772.1 - 0.047 13.8 0.1 11 6.1 0.0 2.4 2 0 0 2 2 2 0 SurA N-terminal domain Sema PF01403.19 EKX48772.1 - 0.067 12.0 0.0 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 Sema domain Phage_int_SAM_2 PF12834.7 EKX48772.1 - 0.077 13.7 0.1 9.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Phage integrase, N-terminal Importin_rep_3 PF18806.1 EKX48772.1 - 0.13 12.3 0.0 51 4.0 0.0 3.7 5 0 0 5 5 5 0 Importin 13 repeat PABP PF00658.18 EKX48772.1 - 0.13 12.5 0.0 8.1 6.7 0.0 2.2 2 0 0 2 2 2 0 Poly-adenylate binding protein, unique domain DnaJ PF00226.31 EKX48773.1 - 0.0017 18.4 0.0 0.0059 16.7 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain DUF5610 PF18433.1 EKX48773.1 - 0.078 13.5 1.9 0.11 13.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5610) Lge1 PF11488.8 EKX48774.1 - 5.9e-06 26.4 26.8 0.081 13.1 3.6 4.8 1 1 4 5 5 5 4 Transcriptional regulatory protein LGE1 Neuromodulin_N PF10580.9 EKX48774.1 - 0.00022 21.0 18.9 18 5.2 0.2 6.4 6 0 0 6 6 6 0 Gap junction protein N-terminal region HALZ PF02183.18 EKX48774.1 - 0.016 15.4 35.2 4.1 7.7 1.2 5.1 5 0 0 5 5 5 0 Homeobox associated leucine zipper SOGA PF11365.8 EKX48774.1 - 0.031 15.4 27.3 1.8e+04 -4.9 27.3 3.8 1 1 0 1 1 0 0 Protein SOGA Gp-FAR-1 PF05823.12 EKX48774.1 - 0.036 14.4 29.3 1.1 9.7 7.6 2.6 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Nuc_rec_co-act PF08815.10 EKX48774.1 - 0.051 13.4 21.5 17 5.4 0.3 5.1 5 0 0 5 5 5 0 Nuclear receptor coactivator DUF285 PF03382.14 EKX48774.1 - 0.085 12.6 2.4 0.11 12.3 2.4 1.2 1 0 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 DUF5082 PF16888.5 EKX48774.1 - 0.13 12.5 38.6 4.2 7.7 5.4 4.4 1 1 3 4 4 4 0 Domain of unknown function (DUF5082) CLZ PF16526.5 EKX48774.1 - 0.19 12.1 34.2 4.8 7.6 8.8 3.7 1 1 4 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TPR_MLP1_2 PF07926.12 EKX48774.1 - 0.22 11.6 47.6 2.3 8.3 16.7 2.9 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Lectin_N PF03954.14 EKX48774.1 - 0.25 11.1 22.4 1.5 8.6 9.8 2.4 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Prefoldin_2 PF01920.20 EKX48774.1 - 0.67 9.9 42.6 0.9 9.5 11.3 3.1 1 1 2 3 3 3 0 Prefoldin subunit SAS4 PF15460.6 EKX48774.1 - 0.87 9.7 27.7 9.1 6.5 1.0 4.9 1 1 4 5 5 5 0 Something about silencing, SAS, complex subunit 4 DASH_Spc19 PF08287.11 EKX48774.1 - 0.91 9.4 35.4 2.4 8.0 22.7 2.6 1 1 1 2 2 2 0 Spc19 DUF668 PF05003.12 EKX48774.1 - 1 9.9 13.8 5.1 7.6 1.3 2.9 1 1 3 4 4 4 0 Protein of unknown function (DUF668) Cep57_CLD_2 PF14197.6 EKX48774.1 - 1.1 9.5 29.3 14 5.9 0.8 5.1 1 1 4 5 5 5 0 Centrosome localisation domain of PPC89 PLAC9 PF15205.6 EKX48774.1 - 1.7 9.1 5.0 37 4.8 0.3 2.5 1 1 3 4 4 4 0 Placenta-specific protein 9 Baculo_PEP_C PF04513.12 EKX48774.1 - 2.4 8.2 15.2 5.5 7.0 5.8 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.8 EKX48774.1 - 2.5 5.5 39.9 2.7 5.4 39.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ApoO PF09769.9 EKX48774.1 - 2.6 8.0 14.6 3.6e+03 -2.1 14.6 2.7 1 1 0 1 1 1 0 Apolipoprotein O DHR10 PF18595.1 EKX48774.1 - 3.3 7.8 46.8 2.5 8.2 23.9 2.1 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain BRE1 PF08647.11 EKX48774.1 - 3.6 7.7 43.3 48 4.1 8.0 3.5 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase DUF743 PF05332.11 EKX48774.1 - 3.8 7.6 14.1 9.1 6.4 1.7 2.8 1 1 3 4 4 4 0 Protein of unknown function (DUF743) XhlA PF10779.9 EKX48774.1 - 4 7.7 37.1 12 6.2 1.9 5.0 1 1 4 5 5 5 0 Haemolysin XhlA Sipho_Gp157 PF05565.11 EKX48774.1 - 5.2 7.1 34.2 7.3 6.6 9.7 2.7 1 1 1 2 2 2 0 Siphovirus Gp157 Nif11 PF07862.11 EKX48774.1 - 5.7 7.3 30.8 12 6.4 5.5 4.6 1 1 4 5 5 5 0 Nif11 domain DUF4600 PF15372.6 EKX48774.1 - 5.8 7.4 34.7 11 6.5 1.6 4.8 1 1 4 5 5 5 0 Domain of unknown function (DUF4600) Spc7 PF08317.11 EKX48774.1 - 7.3 5.4 36.6 9.7 5.0 36.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein baeRF_family2 PF18844.1 EKX48774.1 - 7.5 6.6 15.2 8.7 6.4 1.8 2.8 1 1 3 4 4 4 0 Bacterial archaeo-eukaryotic release factor family 2 Uso1_p115_C PF04871.13 EKX48774.1 - 8.2 6.8 53.0 8.4 6.8 28.1 2.4 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region GnsAB_toxin PF08178.11 EKX48774.1 - 8.2 6.4 28.4 21 5.1 0.3 5.9 6 0 0 6 6 6 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system Drf_DAD PF06345.11 EKX48774.1 - 8.5 6.7 9.3 4.1e+02 1.4 0.1 5.4 5 0 0 5 5 5 0 DRF Autoregulatory Domain DUF1640 PF07798.11 EKX48774.1 - 9.6 6.2 32.8 8.6 6.4 16.8 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Fib_alpha PF08702.10 EKX48775.1 - 0.0004 20.6 32.6 0.035 14.3 14.8 3.3 2 1 1 3 3 3 3 Fibrinogen alpha/beta chain family HetR_C PF18460.1 EKX48775.1 - 0.013 15.4 0.5 0.013 15.4 0.5 2.8 3 0 0 3 3 3 0 Heterocyst differentiation regulator C-terminal Hood domain Laminin_II PF06009.12 EKX48775.1 - 0.056 13.5 22.4 0.12 12.3 8.8 3.5 2 1 1 3 3 3 0 Laminin Domain II Lant_dehydr_C PF14028.6 EKX48775.1 - 0.2 11.1 7.1 0.19 11.2 0.8 2.8 2 2 1 3 3 3 0 Lantibiotic biosynthesis dehydratase C-term Pdase_C33_assoc PF14756.6 EKX48775.1 - 0.35 10.8 4.0 4.3 7.3 2.9 2.7 2 1 0 2 2 2 0 Peptidase_C33-associated domain WHEP-TRS PF00458.20 EKX48775.1 - 0.87 9.8 5.5 5.6 7.2 0.1 3.3 3 0 0 3 3 3 0 WHEP-TRS domain YtxH PF12732.7 EKX48775.1 - 0.9 10.1 5.9 19 5.9 0.0 4.4 3 2 1 4 4 4 0 YtxH-like protein Snapin_Pallidin PF14712.6 EKX48775.1 - 1.8 9.0 25.2 0.67 10.4 6.5 4.7 3 1 0 4 4 4 0 Snapin/Pallidin FlaC_arch PF05377.11 EKX48775.1 - 2.7 8.4 24.0 2.9 8.4 0.9 4.9 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) CLZ PF16526.5 EKX48775.1 - 3.3 8.2 15.2 2.2 8.7 0.9 4.3 4 1 1 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MtrB PF05440.12 EKX48775.1 - 7.2 7.1 5.3 2.8 8.4 0.0 3.0 5 0 0 5 5 5 0 Tetrahydromethanopterin S-methyltransferase subunit B T3SSipB PF16535.5 EKX48775.1 - 7.6 7.0 15.9 1.2 9.6 7.6 3.2 1 1 2 4 4 4 0 Type III cell invasion protein SipB PAS_11 PF14598.6 EKX48776.1 - 0.058 13.5 0.0 0.19 11.9 0.0 1.9 1 1 1 2 2 2 0 PAS domain DUF4384 PF14326.6 EKX48776.1 - 0.2 11.8 0.0 0.45 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4384) TrmO PF01980.16 EKX48777.1 - 2.3e-38 131.1 0.0 3.2e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 tRNA-methyltransferase O Piezo_RRas_bdg PF12166.8 EKX48778.1 - 6.5e-26 91.6 0.5 1.1e-25 90.9 0.5 1.3 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain MatE PF01554.18 EKX48780.1 - 1.6e-39 135.1 24.0 1.3e-19 70.5 9.2 3.4 3 1 1 4 4 4 3 MatE Polysacc_synt_C PF14667.6 EKX48780.1 - 4.8e-07 29.9 3.5 4.8e-07 29.9 3.5 3.3 2 1 0 2 2 2 2 Polysaccharide biosynthesis C-terminal domain TraB PF01963.17 EKX48781.1 - 7.7e-10 39.1 0.2 1.6e-09 38.1 0.2 1.4 1 1 0 1 1 1 1 TraB family RMP PF14996.6 EKX48782.1 - 7.8e-45 152.9 2.2 1.3e-44 152.2 2.2 1.3 1 0 0 1 1 1 1 Retinal Maintenance SAC3_GANP PF03399.16 EKX48784.1 - 7.4e-22 78.1 0.3 4.8e-20 72.1 0.3 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EKX48784.1 - 4.2e-08 33.3 0.0 9.6e-08 32.1 0.0 1.6 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family Ribosom_S12_S23 PF00164.25 EKX48785.1 - 7.6e-50 167.3 0.4 9.1e-50 167.1 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 LRR_6 PF13516.6 EKX48786.1 - 9.7e-24 81.4 18.5 0.00083 19.2 0.3 8.9 9 0 0 9 9 9 7 Leucine Rich repeat LRR_4 PF12799.7 EKX48786.1 - 2.7e-08 34.0 9.3 0.017 15.6 0.6 4.8 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX48786.1 - 2.1e-05 24.4 11.2 1.5 9.7 0.1 6.2 5 2 0 5 5 5 2 Leucine Rich Repeat LRR_2 PF07723.13 EKX48786.1 - 0.017 15.8 3.1 24 5.8 0.1 4.5 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.6 EKX48786.1 - 0.088 12.6 19.6 0.087 12.6 0.9 5.6 3 2 2 5 5 5 0 Leucine rich repeat Ion_trans PF00520.31 EKX48787.1 - 1.2e-118 394.8 64.5 1.1e-38 132.8 8.7 5.1 5 0 0 5 5 5 5 Ion transport protein Nodulin PF02451.15 EKX48787.1 - 0.086 12.3 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 Nodulin LRR_6 PF13516.6 EKX48788.1 - 0.00064 19.6 0.1 0.16 12.1 0.0 3.5 3 0 0 3 3 3 1 Leucine Rich repeat F-box-like PF12937.7 EKX48788.1 - 0.0011 18.8 2.3 0.0017 18.2 0.9 2.1 2 0 0 2 2 2 1 F-box-like DUF4175 PF13779.6 EKX48788.1 - 0.026 12.5 0.8 0.032 12.2 0.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) F-box PF00646.33 EKX48788.1 - 0.043 13.7 1.2 0.11 12.4 1.2 1.7 1 0 0 1 1 1 0 F-box domain U-box PF04564.15 EKX48789.1 - 1.9e-15 56.8 0.0 5.4e-15 55.3 0.0 1.8 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 EKX48789.1 - 0.00069 19.7 0.0 0.0015 18.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein PRKCSH_1 PF13015.6 EKX48789.1 - 0.15 11.7 4.5 0.79 9.4 1.2 2.2 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein MutS_III PF05192.18 EKX48789.1 - 2.4 8.3 9.2 3.5 7.8 9.2 1.4 1 0 0 1 1 1 0 MutS domain III LMBR1 PF04791.16 EKX48789.1 - 3.7 6.4 16.1 4.8 6.0 16.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF572 PF04502.13 EKX48789.1 - 4 7.0 28.7 5.1 6.6 28.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Polysacc_synt_4 PF04669.13 EKX48790.1 - 2.4e-12 46.8 0.0 9e-12 44.9 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis TCTP PF00838.17 EKX48791.1 - 6e-50 169.8 1.8 6.7e-50 169.7 1.8 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein T4_Rnl2_C PF18043.1 EKX48791.1 - 0.068 13.3 0.2 0.11 12.6 0.2 1.4 1 0 0 1 1 1 0 T4 RNA ligase 2 C-terminal HSP90 PF00183.18 EKX48791.1 - 0.07 12.0 0.8 0.099 11.5 0.8 1.2 1 0 0 1 1 1 0 Hsp90 protein SWIM PF04434.17 EKX48793.1 - 0.023 14.3 1.5 0.042 13.5 1.5 1.4 1 0 0 1 1 1 0 SWIM zinc finger Phg_2220_C PF09524.10 EKX48793.1 - 0.072 13.2 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Conserved phage C-terminus (Phg_2220_C) Med1 PF10744.9 EKX48795.1 - 1.8e-07 30.5 2.8 8.1e-07 28.4 1.3 2.3 1 1 1 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 FAM176 PF14851.6 EKX48795.1 - 0.62 9.7 6.1 7.4 6.2 1.0 2.5 2 0 0 2 2 2 0 FAM176 family TPT PF03151.16 EKX48796.1 - 4.1e-14 52.6 24.0 5.3e-14 52.3 24.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EKX48796.1 - 0.015 15.4 31.0 0.069 13.3 15.7 3.6 2 2 0 2 2 2 0 EamA-like transporter family Cation_ATPase_C PF00689.21 EKX48797.1 - 5.3e-46 156.6 0.2 5.3e-46 156.6 0.2 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EKX48797.1 - 2.5e-41 141.2 1.1 2.5e-41 141.2 1.1 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EKX48797.1 - 8.9e-18 65.3 0.0 3.3e-17 63.5 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EKX48797.1 - 7.2e-16 58.1 0.0 1.4e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EKX48797.1 - 9.8e-14 50.8 0.0 3e-13 49.3 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EKX48797.1 - 4.6e-05 23.3 1.3 0.0012 18.6 1.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1772 PF08592.11 EKX48797.1 - 0.061 13.6 0.0 5.1 7.4 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) TLD PF07534.16 EKX48799.1 - 1.2e-35 122.8 0.1 1.3e-35 122.6 0.1 1.0 1 0 0 1 1 1 1 TLD TPR_16 PF13432.6 EKX48800.1 - 7.2e-10 39.4 0.5 0.00013 22.5 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX48800.1 - 1.1e-08 35.2 0.0 0.00012 22.2 0.0 2.3 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EKX48800.1 - 3.4e-08 33.0 0.2 0.015 15.3 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX48800.1 - 1.8e-07 31.4 3.1 0.047 14.5 0.0 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 EKX48800.1 - 6.8e-06 26.4 0.0 0.095 13.4 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX48800.1 - 1.2e-05 24.9 0.0 0.088 12.5 0.0 3.1 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.28 EKX48800.1 - 2.9e-05 23.7 0.0 0.086 12.7 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX48800.1 - 3.7e-05 24.2 0.0 0.15 12.6 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX48800.1 - 0.00031 20.6 0.1 0.56 10.4 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX48800.1 - 0.0012 19.1 0.6 1 9.7 0.1 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX48800.1 - 0.011 16.1 0.0 0.075 13.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX48800.1 - 0.011 15.5 0.2 2.4 8.2 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 EKX48800.1 - 0.065 13.6 1.6 3.9 7.9 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat G2BR PF18442.1 EKX48800.1 - 0.27 10.9 3.1 0.27 10.9 0.9 2.2 2 0 0 2 2 2 0 E3 gp78 Ube2g2-binding region (G2BR) TPR_4 PF07721.14 EKX48800.1 - 0.45 11.3 7.8 10 7.1 0.9 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_transf_41 PF13844.6 EKX48801.1 - 2.2e-18 66.0 0.0 1.5e-17 63.2 0.0 1.8 2 0 0 2 2 2 2 Glycosyl transferase family 41 Not3 PF04065.15 EKX48802.1 - 0.098 12.1 3.2 0.3 10.5 0.2 2.3 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component DUF3275 PF11679.8 EKX48802.1 - 2.5 8.0 7.8 0.46 10.4 0.7 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3275) DivIC PF04977.15 EKX48802.1 - 4.4 7.2 6.5 10 6.0 1.2 2.8 2 1 0 2 2 2 0 Septum formation initiator Metallophos PF00149.28 EKX48804.1 - 1.3e-14 55.2 0.4 2.5e-14 54.3 0.4 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 EKX48804.1 - 8.8e-14 51.9 0.0 1.9e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain fn3_PAP PF17808.1 EKX48804.1 - 3.4e-07 30.4 0.1 7.3e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 Fn3-like domain from Purple Acid Phosphatase Metallophos_C PF14008.6 EKX48804.1 - 1.6e-05 25.7 1.7 1.6e-05 25.7 0.0 2.0 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.10 EKX48804.1 - 0.0096 15.0 0.2 0.22 10.5 0.0 2.2 2 0 0 2 2 2 1 PhoD-like phosphatase HECW_N PF16562.5 EKX48804.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 UbiA PF01040.18 EKX48805.1 - 5.6e-32 111.0 16.1 7e-32 110.7 16.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF2975 PF11188.8 EKX48805.1 - 0.25 11.2 9.6 0.058 13.3 5.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) CPP1-like PF11833.8 EKX48805.1 - 6.4 6.4 8.8 10 5.7 4.8 2.2 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like HSP70 PF00012.20 EKX48806.1 - 2.7e-142 475.0 3.7 1.5e-71 241.4 0.4 1.9 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EKX48806.1 - 4.2e-06 25.8 4.6 0.037 12.9 0.4 3.8 3 1 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 EKX48806.1 - 0.013 15.2 1.0 0.1 12.3 0.5 2.5 2 1 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 EKX48806.1 - 0.022 13.8 0.0 0.57 9.1 0.0 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.6 EKX48806.1 - 0.042 14.3 0.5 10 6.6 0.0 3.7 3 2 0 3 3 3 0 Cell division protein FtsA JmjC PF02373.22 EKX48807.1 - 8.6e-10 39.1 0.0 0.00047 20.6 0.0 2.5 2 0 0 2 2 2 2 JmjC domain, hydroxylase Glyco_transf_25 PF01755.17 EKX48807.1 - 4e-06 26.8 0.0 3.2e-05 23.9 0.0 2.5 2 1 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) Cupin_4 PF08007.12 EKX48807.1 - 0.0011 18.6 0.0 0.0022 17.5 0.0 1.5 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 EKX48807.1 - 0.0013 18.6 0.0 0.0037 17.0 0.0 1.8 1 1 0 1 1 1 1 Cupin-like domain F-box-like PF12937.7 EKX48807.1 - 0.0047 16.8 0.0 0.015 15.2 0.0 1.9 1 0 0 1 1 1 1 F-box-like Cupin_2 PF07883.11 EKX48807.1 - 0.013 15.2 0.0 0.082 12.6 0.0 2.2 2 0 0 2 2 2 0 Cupin domain Cupin_1 PF00190.22 EKX48807.1 - 0.19 11.3 0.0 0.38 10.4 0.0 1.4 1 0 0 1 1 1 0 Cupin Tim54 PF11711.8 EKX48807.1 - 0.28 9.9 2.0 0.57 8.9 2.0 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PH PF00169.29 EKX48808.1 - 9.4e-15 55.0 0.1 1.7e-14 54.2 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EKX48808.1 - 1.3e-06 28.6 0.1 4e-06 27.0 0.1 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 EKX48808.1 - 2.5e-06 27.9 1.1 7e-05 23.2 1.1 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain Ank_4 PF13637.6 EKX48810.1 - 1.7e-06 28.4 0.1 2.3e-05 24.8 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX48810.1 - 6.6e-06 26.3 0.0 0.00012 22.3 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX48810.1 - 7.8e-05 22.8 0.0 0.0067 16.9 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EKX48810.1 - 8.2e-05 22.9 0.0 0.0021 18.4 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 EKX48810.1 - 8.5e-05 23.1 0.0 0.0011 19.5 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) TPR_1 PF00515.28 EKX48811.1 - 2.2e-11 43.0 12.6 0.0012 18.6 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX48811.1 - 6.2e-11 41.5 21.3 0.00018 21.3 0.1 6.8 7 0 0 7 7 6 3 Tetratricopeptide repeat DnaJ PF00226.31 EKX48811.1 - 1e-09 38.4 1.8 2.6e-08 33.9 0.1 2.9 2 0 0 2 2 2 1 DnaJ domain TPR_8 PF13181.6 EKX48811.1 - 3.4e-07 30.0 2.2 2.2 8.7 0.0 5.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX48811.1 - 8.2e-07 29.3 14.4 0.12 13.2 0.2 6.6 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX48811.1 - 0.00034 20.4 4.7 1 9.6 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX48811.1 - 0.00041 20.5 1.8 3.6 7.9 0.0 4.1 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EKX48811.1 - 0.00052 20.6 14.7 0.96 10.2 0.1 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX48811.1 - 0.015 15.9 4.0 2.1 9.2 0.0 4.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX48811.1 - 0.019 15.3 16.6 0.26 11.6 3.3 5.6 3 2 2 5 5 5 0 Tetratricopeptide repeat PCEMA1 PF07418.11 EKX48811.1 - 0.02 14.4 3.9 0.055 13.0 3.9 1.9 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 TPR_11 PF13414.6 EKX48811.1 - 0.035 13.8 4.8 9.4 6.0 0.0 4.7 5 0 0 5 5 5 0 TPR repeat TPR_19 PF14559.6 EKX48811.1 - 0.048 14.2 20.5 1.5 9.3 0.3 6.7 7 1 0 7 7 6 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 EKX48811.1 - 0.054 13.0 1.7 4.6 6.8 0.1 3.6 3 1 1 4 4 4 0 SHNi-TPR Fis1_TPR_C PF14853.6 EKX48811.1 - 0.058 13.5 5.4 13 5.9 0.3 4.5 4 1 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF5113 PF17140.4 EKX48811.1 - 0.081 12.7 0.3 4.4 7.1 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) TPR_10 PF13374.6 EKX48811.1 - 0.17 11.8 15.6 6 6.9 0.4 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DrsE PF02635.15 EKX48811.1 - 0.29 11.5 1.8 5.1 7.5 0.2 2.6 2 0 0 2 2 2 0 DsrE/DsrF-like family DUF1910 PF08928.10 EKX48811.1 - 0.71 9.9 4.7 0.57 10.2 1.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) TPR_9 PF13371.6 EKX48811.1 - 0.93 9.7 10.2 1.5 9.0 1.9 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Ammonium_transp PF00909.21 EKX48813.1 - 9e-103 344.0 25.0 9.9e-103 343.9 25.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family TAT_signal PF10518.9 EKX48815.1 - 0.18 11.7 0.7 0.33 10.9 0.7 1.5 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence DUF2681 PF10883.8 EKX48816.1 - 8.5 6.9 7.9 0.6 10.5 0.5 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2681) Fer4_10 PF13237.6 EKX48817.1 - 0.017 15.2 5.3 0.04 14.1 5.3 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain HnRNP_M PF11532.8 EKX48817.1 - 0.051 13.8 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein M Fer4_9 PF13187.6 EKX48817.1 - 0.81 9.9 5.7 1.7 8.9 5.7 1.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain TPR_2 PF07719.17 EKX48818.1 - 0.0022 17.9 0.4 1.7 8.9 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX48818.1 - 0.019 15.7 0.0 11 7.2 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EKX48818.1 - 0.2 11.5 0.6 19 5.3 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Endonuc_Holl PF10107.9 EKX48819.1 - 0.0019 18.0 2.3 0.0031 17.4 2.3 1.2 1 0 0 1 1 1 1 Endonuclease related to archaeal Holliday junction resolvase DUF812 PF05667.11 EKX48819.1 - 0.0031 16.5 3.3 0.0037 16.2 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Leu_zip PF15294.6 EKX48819.1 - 0.0052 16.3 7.2 0.0082 15.7 7.2 1.2 1 0 0 1 1 1 1 Leucine zipper DUF724 PF05266.14 EKX48819.1 - 0.0089 15.9 6.4 0.013 15.3 6.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF724) AKNA PF12443.8 EKX48819.1 - 0.0094 16.6 7.1 0.11 13.1 0.1 2.4 1 1 1 2 2 2 1 AT-hook-containing transcription factor DUF2935 PF11155.8 EKX48819.1 - 0.014 15.7 0.9 0.049 14.0 0.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) DUF3600 PF12207.8 EKX48819.1 - 0.014 15.3 1.1 0.03 14.3 0.6 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3600) TolA_bind_tri PF16331.5 EKX48819.1 - 0.021 14.9 1.5 0.058 13.5 1.5 1.7 1 0 0 1 1 1 0 TolA binding protein trimerisation GOLGA2L5 PF15070.6 EKX48819.1 - 0.028 13.1 5.7 0.021 13.5 4.3 1.4 2 0 0 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 DUF2203 PF09969.9 EKX48819.1 - 0.05 14.3 1.3 5 7.9 0.5 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF1018 PF06252.12 EKX48819.1 - 0.088 13.8 3.4 0.29 12.1 3.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) DUF4446 PF14584.6 EKX48819.1 - 0.095 12.7 6.1 0.17 11.9 2.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) XhlA PF10779.9 EKX48819.1 - 0.12 12.6 9.9 0.12 12.6 4.5 2.4 1 1 1 2 2 2 0 Haemolysin XhlA LMBR1 PF04791.16 EKX48819.1 - 0.13 11.1 1.5 0.16 10.9 1.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TMA7 PF09072.10 EKX48819.1 - 0.2 12.5 2.4 0.36 11.7 2.4 1.4 1 0 0 1 1 1 0 Translation machinery associated TMA7 DUF1664 PF07889.12 EKX48819.1 - 0.31 11.1 2.3 1.9 8.5 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF641 PF04859.12 EKX48819.1 - 0.32 11.3 5.1 0.77 10.1 5.1 1.6 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF3450 PF11932.8 EKX48819.1 - 0.35 10.1 6.2 0.84 8.9 2.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) GIT_CC PF16559.5 EKX48819.1 - 0.37 10.7 5.1 0.86 9.5 5.1 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor MCU PF04678.13 EKX48819.1 - 0.41 10.7 4.6 17 5.5 0.1 2.2 1 1 1 2 2 2 0 Mitochondrial calcium uniporter Rop-like PF05082.13 EKX48819.1 - 0.6 10.0 8.4 4.9 7.0 0.5 3.6 3 0 0 3 3 3 0 Rop-like ADIP PF11559.8 EKX48819.1 - 0.76 9.9 9.7 0.11 12.5 5.4 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Plk4_PB2 PF18409.1 EKX48819.1 - 0.76 10.5 6.7 2.4 8.9 0.1 2.7 1 1 2 3 3 3 0 Polo-like Kinase 4 Polo Box 2 KASH_CCD PF14662.6 EKX48819.1 - 0.99 9.2 12.1 0.55 10.0 7.9 1.9 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH TMF_DNA_bd PF12329.8 EKX48819.1 - 1 9.4 8.9 0.44 10.6 6.0 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 EKX48819.1 - 1.1 9.1 7.2 0.69 9.7 4.1 2.3 3 0 0 3 3 2 0 Septum formation initiator GCN5L1 PF06320.13 EKX48819.1 - 1.7 8.8 7.6 1.1 9.4 3.7 2.4 2 1 1 3 3 3 0 GCN5-like protein 1 (GCN5L1) TMPIT PF07851.13 EKX48819.1 - 2.2 7.4 8.0 3.3 6.9 7.8 1.4 1 1 0 1 1 1 0 TMPIT-like protein FlxA PF14282.6 EKX48819.1 - 2.6 8.1 8.3 0.54 10.3 3.3 2.1 2 0 0 2 2 2 0 FlxA-like protein YlqD PF11068.8 EKX48819.1 - 2.9 8.3 8.9 53 4.2 10.1 2.3 2 1 0 2 2 2 0 YlqD protein FapA PF03961.13 EKX48819.1 - 3.5 6.1 7.9 6.8 5.2 7.7 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A Csm1_N PF18504.1 EKX48819.1 - 5 7.5 11.3 2.7 8.4 3.8 3.0 2 1 1 3 3 3 0 Csm1 N-terminal domain DUF4795 PF16043.5 EKX48819.1 - 5.4 6.6 12.0 14 5.3 12.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) UPF0242 PF06785.11 EKX48819.1 - 6.5 6.8 11.6 19 5.3 10.6 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Ion_trans PF00520.31 EKX48820.1 - 4.4e-14 52.3 14.1 2.3e-12 46.7 4.4 2.2 1 1 1 2 2 2 2 Ion transport protein EF-hand_1 PF00036.32 EKX48820.1 - 4.4e-06 25.9 0.3 0.00038 19.8 0.1 2.9 2 0 0 2 2 2 1 EF hand PH PF00169.29 EKX48820.1 - 1.1e-05 25.9 0.1 2.2e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 PH domain EF-hand_6 PF13405.6 EKX48820.1 - 0.00022 20.9 0.3 0.012 15.5 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 EKX48820.1 - 0.00044 19.6 0.1 0.0011 18.4 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EKX48820.1 - 0.0012 19.2 2.6 0.006 17.0 0.1 3.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 EKX48820.1 - 0.0044 16.9 1.4 0.074 12.9 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain pair Nup88 PF10168.9 EKX48820.1 - 0.098 10.5 5.3 0.16 9.7 5.3 1.3 1 0 0 1 1 1 0 Nuclear pore component Plasmid_RAQPRD PF09686.10 EKX48820.1 - 0.9 9.8 4.2 0.97 9.7 1.2 2.7 2 1 1 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Sec34 PF04136.15 EKX48820.1 - 2.2 8.2 7.3 24 4.8 0.9 3.6 3 0 0 3 3 3 0 Sec34-like family Spore_III_AB PF09548.10 EKX48820.1 - 4.7 7.3 10.9 22 5.1 4.0 3.2 3 1 1 4 4 4 0 Stage III sporulation protein AB (spore_III_AB) LRR_6 PF13516.6 EKX48821.1 - 1.6e-05 24.5 11.3 0.00022 21.0 0.7 3.9 4 0 0 4 4 4 2 Leucine Rich repeat zf-RRPl_C4 PF17026.5 EKX48822.1 - 0.061 13.4 0.1 0.061 13.4 0.1 2.3 2 1 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type JHY PF15261.6 EKX48822.1 - 0.071 13.8 4.6 0.15 12.7 4.6 1.5 1 0 0 1 1 1 0 Jhy protein PhoD PF09423.10 EKX48825.1 - 8.3e-17 61.2 0.0 1.5e-16 60.4 0.0 1.4 1 1 1 2 2 2 1 PhoD-like phosphatase Tropomyosin_1 PF12718.7 EKX48826.1 - 0.0086 16.2 7.0 0.012 15.8 7.0 1.2 1 0 0 1 1 1 1 Tropomyosin like ZapB PF06005.12 EKX48826.1 - 0.0098 16.3 1.4 0.0098 16.3 1.4 2.1 1 1 1 2 2 2 1 Cell division protein ZapB DrsE_2 PF13686.6 EKX48826.1 - 0.21 11.5 0.9 3.5 7.5 0.9 2.1 1 1 0 1 1 1 0 DsrE/DsrF/DrsH-like family TPR_MLP1_2 PF07926.12 EKX48826.1 - 0.27 11.3 8.1 0.089 12.9 4.4 1.9 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein PDZ_6 PF17820.1 EKX48827.1 - 1.7e-05 24.6 0.0 4.6e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX48827.1 - 0.00081 19.7 1.4 0.001 19.4 0.1 1.9 3 0 0 3 3 3 1 PDZ domain SRR1 PF07985.12 EKX48827.1 - 0.058 13.4 0.0 0.21 11.7 0.0 1.9 2 0 0 2 2 2 0 SRR1 zf-AD PF07776.15 EKX48828.1 - 0.00017 21.7 0.1 0.00019 21.6 0.1 1.1 1 0 0 1 1 1 1 Zinc-finger associated domain (zf-AD) TMF_DNA_bd PF12329.8 EKX48829.1 - 0.0013 18.7 1.7 0.0013 18.7 1.7 5.7 4 2 1 5 5 5 2 TATA element modulatory factor 1 DNA binding Med3 PF11593.8 EKX48829.1 - 0.0019 17.5 3.3 0.019 14.2 0.6 2.6 2 1 0 2 2 2 1 Mediator complex subunit 3 fungal BRE1 PF08647.11 EKX48829.1 - 0.015 15.4 1.0 0.015 15.4 1.0 5.8 3 3 2 5 5 5 0 BRE1 E3 ubiquitin ligase DUF244 PF03112.14 EKX48829.1 - 0.015 15.1 1.1 0.092 12.6 0.1 2.6 2 1 1 3 3 3 0 Uncharacterized protein family (ORF7) DUF RPW8 PF05659.11 EKX48829.1 - 0.02 14.6 0.8 0.02 14.6 0.8 3.8 3 1 3 6 6 6 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 TMF_TATA_bd PF12325.8 EKX48829.1 - 0.023 14.9 2.2 0.023 14.9 2.2 6.1 1 1 6 7 7 7 0 TATA element modulatory factor 1 TATA binding HALZ PF02183.18 EKX48829.1 - 0.04 14.1 0.1 0.04 14.1 0.1 8.0 10 0 0 10 10 10 0 Homeobox associated leucine zipper DUF1192 PF06698.11 EKX48829.1 - 0.08 13.0 17.4 0.28 11.3 0.3 5.5 3 2 3 6 6 6 0 Protein of unknown function (DUF1192) NPV_P10 PF05531.12 EKX48829.1 - 2 8.9 14.8 1.5 9.4 0.3 5.0 3 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein Taq-exonuc PF09281.10 EKX48829.1 - 2.8 8.0 7.9 0.18 11.8 0.5 2.7 1 1 2 3 3 3 0 Taq polymerase, exonuclease JIP_LZII PF16471.5 EKX48829.1 - 3.8 7.7 32.7 5.2 7.3 6.9 6.3 5 2 1 6 6 6 0 JNK-interacting protein leucine zipper II Baculo_PEP_C PF04513.12 EKX48829.1 - 3.9 7.5 16.4 3.4 7.7 1.4 4.0 3 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus MutS_II PF05188.17 EKX48830.1 - 0.12 12.7 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 MutS domain II Kinesin_assoc PF16183.5 EKX48830.1 - 0.2 11.8 1.7 0.23 11.6 0.4 1.7 2 0 0 2 2 2 0 Kinesin-associated ATG16 PF08614.11 EKX48830.1 - 0.39 10.9 10.5 0.051 13.8 5.5 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Sfi1 PF08457.10 EKX48830.1 - 1 7.8 33.5 0.046 12.2 24.3 3.0 2 2 0 2 2 2 0 Sfi1 spindle body protein QueC PF06508.13 EKX48831.1 - 2.1e-34 118.9 0.0 1.5e-33 116.1 0.0 2.2 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC RWP-RK PF02042.15 EKX48831.1 - 6.3e-13 48.5 0.7 1.3e-12 47.5 0.1 1.8 2 0 0 2 2 2 1 RWP-RK domain ATP_bind_3 PF01171.20 EKX48831.1 - 0.0018 18.1 0.0 0.016 15.0 0.0 2.3 1 1 0 1 1 1 1 PP-loop family DUF3301 PF11743.8 EKX48831.1 - 0.016 14.9 0.0 0.048 13.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) HTH_8 PF02954.19 EKX48831.1 - 0.032 14.0 0.2 1.1 9.2 0.1 2.6 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family HTH_6 PF01418.17 EKX48831.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family PTEN_C2 PF10409.9 EKX48832.1 - 9.5e-06 25.4 0.1 1.8e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 EKX48832.1 - 0.0073 16.1 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF4354 PF14263.6 EKX48832.1 - 0.13 12.0 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) COX6C PF02937.15 EKX48833.1 - 0.051 13.7 0.0 0.064 13.4 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc Beach PF02138.18 EKX48834.1 - 1.2e-123 411.9 0.0 1.4e-123 411.6 0.0 1.0 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 EKX48834.1 - 6.3e-10 39.1 0.0 1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4880 PF16220.5 EKX48834.1 - 0.17 11.8 1.5 0.33 10.9 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4880) DUF3668 PF12416.8 EKX48835.1 - 0.09 12.6 0.1 0.24 11.2 0.1 1.6 2 0 0 2 2 2 0 Cep120 protein Beta_helix PF13229.6 EKX48837.1 - 3e-08 33.7 0.3 3.8e-07 30.1 0.3 2.2 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 EKX48837.1 - 0.0002 20.7 0.3 0.0032 16.8 0.0 2.3 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.11 EKX48837.1 - 0.00028 20.3 0.0 0.00067 19.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1565) Chlam_PMP PF02415.17 EKX48837.1 - 0.62 10.7 16.0 18 6.1 1.7 4.9 5 0 0 5 5 5 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Glyco_hydro_47 PF01532.20 EKX48838.1 - 1.1e-100 337.8 0.0 1.5e-100 337.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 RAB3GAP2_C PF14656.6 EKX48838.1 - 0.11 10.7 0.3 0.16 10.2 0.3 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Mito_carr PF00153.27 EKX48839.1 - 2.4e-68 226.1 2.8 2.1e-22 78.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 EKX48839.1 - 0.0024 18.0 0.0 5.7 7.2 0.0 3.2 3 1 0 3 3 3 2 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Bestrophin PF01062.21 EKX48840.1 - 1.6e-13 50.8 0.3 3.6e-13 49.6 0.0 1.7 2 0 0 2 2 2 1 Bestrophin, RFP-TM, chloride channel DUF4834 PF16118.5 EKX48840.1 - 0.022 15.7 1.6 3.9 8.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) PDZ PF00595.24 EKX48841.1 - 2.6e-07 30.9 0.3 2.3e-06 27.9 0.2 2.3 1 1 1 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EKX48841.1 - 3.3e-06 26.9 0.1 8.8e-06 25.5 0.1 1.7 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 EKX48841.1 - 0.00025 21.4 0.0 0.00038 20.8 0.0 1.4 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 EKX48841.1 - 0.00025 21.3 0.0 0.00055 20.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain DEAD_2 PF06733.15 EKX48841.1 - 0.0047 16.6 0.3 0.0061 16.2 0.3 1.1 1 0 0 1 1 1 1 DEAD_2 DUF4110 PF13422.6 EKX48841.1 - 0.0067 16.5 0.2 0.014 15.4 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4110) HhH-GPD PF00730.25 EKX48841.1 - 0.081 13.4 0.1 7.2 7.1 0.1 2.2 1 1 1 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein Peptidase_C50 PF03568.17 EKX48842.1 - 7.4e-08 31.9 0.1 2.3e-07 30.3 0.1 1.8 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.6 EKX48842.1 - 2.7e-07 30.8 2.3 0.00032 20.9 0.3 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat CHAT PF12770.7 EKX48842.1 - 0.011 15.1 2.5 0.28 10.5 0.2 3.2 3 0 0 3 3 3 0 CHAT domain TPR_14 PF13428.6 EKX48842.1 - 0.19 12.6 3.5 17 6.6 0.0 5.5 4 0 0 4 4 4 0 Tetratricopeptide repeat XG_FTase PF03254.13 EKX48843.1 - 0.00031 19.5 0.0 0.00032 19.4 0.0 1.0 1 0 0 1 1 1 1 Xyloglucan fucosyltransferase PPR_2 PF13041.6 EKX48844.1 - 7.6e-60 198.9 24.7 2e-12 47.1 0.0 9.7 3 3 7 10 10 10 9 PPR repeat family PPR PF01535.20 EKX48844.1 - 1.7e-51 168.9 21.3 5.6e-06 26.3 0.5 12.3 10 2 1 12 12 12 10 PPR repeat PPR_3 PF13812.6 EKX48844.1 - 9.1e-48 160.2 0.2 7.4e-12 45.2 0.0 5.8 4 1 1 6 6 6 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 EKX48844.1 - 2e-47 158.5 0.6 1.4e-06 27.9 0.0 10.5 10 0 0 10 10 10 9 PPR repeat PPR_long PF17177.4 EKX48844.1 - 4.9e-27 94.7 2.8 1.2e-11 44.5 0.2 3.7 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP MRP-S27 PF10037.9 EKX48844.1 - 6.9e-09 35.0 1.5 0.023 13.6 0.0 4.3 2 2 2 4 4 4 2 Mitochondrial 28S ribosomal protein S27 TPR_19 PF14559.6 EKX48844.1 - 3.9e-06 27.3 2.0 1.5 9.4 0.0 5.5 5 1 2 7 7 7 1 Tetratricopeptide repeat SPOB_a PF14689.6 EKX48844.1 - 0.00026 20.6 4.3 7.1 6.4 0.0 6.0 7 0 0 7 7 7 1 Sensor_kinase_SpoOB-type, alpha-helical domain Clathrin PF00637.20 EKX48844.1 - 0.00051 19.9 2.7 3 7.7 0.3 4.5 3 2 1 5 5 5 2 Region in Clathrin and VPS RPM2 PF08579.11 EKX48844.1 - 0.012 16.0 0.0 0.68 10.3 0.0 3.6 2 1 2 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) DUF4003 PF13170.6 EKX48844.1 - 0.018 14.4 0.2 0.31 10.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4003) ECSIT PF06239.11 EKX48844.1 - 0.021 13.9 0.2 5.4 6.1 0.0 3.7 3 1 1 4 4 4 0 Evolutionarily conserved signalling intermediate in Toll pathway Mic1 PF07035.12 EKX48844.1 - 0.035 13.8 0.9 2.6 7.7 0.1 2.6 2 0 0 2 2 2 0 Colon cancer-associated protein Mic1-like ChAPs PF09295.10 EKX48844.1 - 0.039 12.9 0.1 0.15 11.0 0.0 2.0 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_8 PF13181.6 EKX48844.1 - 2.8 8.4 6.4 1.3e+02 3.1 0.0 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat cNMP_binding PF00027.29 EKX48845.1 - 5.8e-15 55.1 0.0 9.4e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EKX48845.1 - 9.9e-15 54.3 1.5 9.9e-15 54.3 1.5 2.8 3 0 0 3 3 3 1 Ion channel GT-D PF08759.11 EKX48845.1 - 0.062 13.0 0.4 0.11 12.2 0.4 1.3 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold Cyt-b5 PF00173.28 EKX48846.1 - 0.0042 17.2 0.0 0.0076 16.4 0.0 1.5 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain tRNA_anti-codon PF01336.25 EKX48846.1 - 0.11 12.6 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain VHL PF01847.16 EKX48847.1 - 2.3e-05 24.2 0.0 4.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 VHL beta domain Enkurin PF13864.6 EKX48848.1 - 2.6e-08 34.2 1.1 2.6e-08 34.2 1.1 2.0 2 0 0 2 2 2 1 Calmodulin-binding Bap31_Bap29_C PF18035.1 EKX48848.1 - 0.0034 17.3 1.5 0.0062 16.5 0.1 2.2 3 0 0 3 3 3 1 Bap31/Bap29 cytoplasmic coiled-coil domain TOC159_MAD PF11886.8 EKX48848.1 - 0.1 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Translocase of chloroplast 159/132, membrane anchor domain APG6_N PF17675.1 EKX48848.1 - 0.96 10.0 6.2 2.1 8.9 2.5 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region PHD PF00628.29 EKX48849.1 - 5.7e-05 22.9 17.1 5.7e-05 22.9 17.1 2.2 2 0 0 2 2 2 1 PHD-finger ubiquitin PF00240.23 EKX48850.1 - 2.2e-09 36.9 0.3 3.5e-09 36.3 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 EKX48850.1 - 0.014 15.5 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EKX48850.1 - 0.031 14.9 0.0 0.039 14.5 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ribosomal_L1 PF00687.21 EKX48851.1 - 2.9e-40 138.2 0.0 3.9e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Sel1 PF08238.12 EKX48852.1 - 5.5e-14 52.3 0.9 0.003 18.2 0.2 4.8 5 0 0 5 5 5 3 Sel1 repeat fn3 PF00041.21 EKX48853.1 - 7e-18 64.8 0.8 0.00017 21.9 0.0 5.3 5 0 0 5 5 5 3 Fibronectin type III domain LysM PF01476.20 EKX48853.1 - 4.6e-07 29.8 0.3 0.022 14.8 0.0 3.6 3 0 0 3 3 3 2 LysM domain Filamin PF00630.19 EKX48853.1 - 0.0059 17.4 0.0 14 6.6 0.0 4.9 5 0 0 5 5 5 1 Filamin/ABP280 repeat Velvet PF11754.8 EKX48853.1 - 0.48 10.3 4.7 1 9.3 0.2 3.5 3 1 0 3 3 3 0 Velvet factor DUF2800 PF10926.8 EKX48854.1 - 0.16 11.2 0.1 0.16 11.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) UDPGP PF01704.18 EKX48855.1 - 8.9e-23 80.6 0.0 1.3e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Alpha_kinase PF02816.18 EKX48857.1 - 9.8e-56 188.8 0.7 1.3e-55 188.4 0.0 1.6 2 0 0 2 2 2 1 Alpha-kinase family PDZ_6 PF17820.1 EKX48857.1 - 5.8e-13 48.5 1.6 8.3e-13 48.0 0.2 2.0 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX48857.1 - 5.8e-08 33.0 1.1 5.8e-08 33.0 1.1 1.7 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX48857.1 - 5.2e-05 23.5 0.3 0.00016 21.9 0.3 1.9 1 0 0 1 1 1 1 PDZ domain NHL PF01436.21 EKX48859.1 - 7e-20 70.0 2.2 6.2e-06 26.0 0.0 6.0 5 1 0 5 5 5 4 NHL repeat SGL PF08450.12 EKX48859.1 - 6.9e-05 22.6 0.0 0.12 11.9 0.0 3.1 3 1 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Phytase-like PF13449.6 EKX48859.1 - 0.00012 22.1 0.0 0.016 15.2 0.0 3.1 2 1 0 2 2 2 1 Esterase-like activity of phytase Lactonase PF10282.9 EKX48859.1 - 0.00013 21.4 0.0 0.93 8.7 0.0 3.6 1 1 3 4 4 4 2 Lactonase, 7-bladed beta-propeller Arylesterase PF01731.20 EKX48859.1 - 0.00048 20.3 0.0 3.5 7.9 0.0 3.9 4 0 0 4 4 4 2 Arylesterase Str_synth PF03088.16 EKX48859.1 - 0.0017 18.4 0.0 0.054 13.6 0.0 2.7 2 0 0 2 2 2 1 Strictosidine synthase Coatomer_WDAD PF04053.14 EKX48859.1 - 0.17 10.9 0.0 2 7.4 0.0 2.4 2 1 1 3 3 3 0 Coatomer WD associated region Pes-10 PF07149.11 EKX48860.1 - 0.024 13.7 0.0 0.033 13.3 0.0 1.1 1 0 0 1 1 1 0 Pes-10 NPFF PF15085.6 EKX48860.1 - 0.062 13.6 1.0 14 6.0 0.6 2.3 2 0 0 2 2 2 0 Neuropeptide FF Glyco_transf_10 PF00852.19 EKX48861.1 - 2.7e-28 98.9 0.1 1.6e-27 96.4 0.0 2.0 1 1 1 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 EKX48861.1 - 0.032 14.7 0.2 0.058 13.8 0.2 1.4 1 0 0 1 1 1 0 Fucosyltransferase, N-terminal RRM_1 PF00076.22 EKX48863.1 - 4.6e-18 64.8 0.0 5.7e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-HC5HC2H_2 PF13832.6 EKX48864.1 - 1.2e-18 67.2 1.2 1.2e-18 67.2 1.2 1.9 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EKX48864.1 - 1.2e-11 44.7 1.0 1.2e-11 44.7 1.0 2.3 2 0 0 2 2 2 1 PHD-like zinc-binding domain Spc7 PF08317.11 EKX48866.1 - 0.0036 16.2 21.3 0.005 15.8 21.3 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 EKX48866.1 - 0.14 11.7 15.3 0.24 10.9 15.3 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 EKX48866.1 - 0.72 8.9 17.2 0.83 8.7 17.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FUSC PF04632.12 EKX48866.1 - 0.78 8.2 7.1 0.92 8.0 7.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family LemA PF04011.12 EKX48866.1 - 0.84 9.5 9.7 0.58 10.0 8.1 1.5 1 1 0 1 1 1 0 LemA family DUF4407 PF14362.6 EKX48866.1 - 0.99 8.7 17.0 1.4 8.2 17.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1925 PF09094.11 EKX48866.1 - 1.1 9.6 3.1 0.89 9.9 0.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1925) ACP_PD PF04336.12 EKX48866.1 - 1.1 9.7 4.9 0.86 10.1 2.3 1.9 1 1 1 2 2 2 0 Acyl carrier protein phosphodiesterase Nup88 PF10168.9 EKX48866.1 - 1.5 6.6 20.0 1.8 6.3 20.0 1.0 1 0 0 1 1 1 0 Nuclear pore component MCD_N PF17408.2 EKX48866.1 - 1.7 8.8 7.4 1.2 9.3 0.4 2.8 1 1 2 3 3 3 0 Malonyl-CoA decarboxylase N-terminal domain CPP1-like PF11833.8 EKX48866.1 - 2.3 7.8 8.5 3.7 7.2 8.1 1.5 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DHR10 PF18595.1 EKX48866.1 - 5.1 7.2 33.2 4.2 7.4 10.7 2.2 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain SPOUT_MTase PF02590.17 EKX48866.1 - 5.3 7.0 13.3 61 3.5 13.3 2.1 1 1 0 1 1 1 0 Predicted SPOUT methyltransferase Vps39_1 PF10366.9 EKX48867.1 - 7.8 6.8 7.2 2.4 8.5 3.9 1.8 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Kelch_1 PF01344.25 EKX48869.1 - 4.5e-40 135.0 0.5 8.2e-16 57.3 0.0 4.8 4 1 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 EKX48869.1 - 1.2e-18 66.7 0.8 5.3e-07 29.7 0.0 4.8 3 1 1 4 4 4 4 Kelch motif Kelch_3 PF13415.6 EKX48869.1 - 1.5e-12 47.4 7.5 5.9e-05 23.2 0.0 5.2 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_4 PF13418.6 EKX48869.1 - 5.9e-12 45.4 0.4 1.5e-06 28.1 0.0 4.2 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 EKX48869.1 - 1.7e-08 34.1 2.2 0.0061 16.5 0.0 4.1 4 1 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 EKX48869.1 - 5.9e-08 32.5 0.5 0.0059 16.6 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Spermine_synth PF01564.17 EKX48869.1 - 0.14 11.5 0.2 1.4 8.3 0.1 2.2 2 0 0 2 2 2 0 Spermine/spermidine synthase domain DUF3649 PF12365.8 EKX48871.1 - 0.071 12.8 1.0 0.071 12.8 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) DUF2976 PF11190.8 EKX48871.1 - 0.14 12.0 0.5 1.9 8.3 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2976) HTH_33 PF13592.6 EKX48873.1 - 0.0058 16.2 5.5 9.5 5.9 0.1 4.1 4 0 0 4 4 4 3 Winged helix-turn helix SBP PF03110.14 EKX48874.1 - 0.025 14.9 0.0 0.052 13.9 0.0 1.5 1 0 0 1 1 1 0 SBP domain SET PF00856.28 EKX48874.1 - 0.61 10.5 3.4 0.31 11.4 0.3 1.9 1 1 0 2 2 2 0 SET domain WD40 PF00400.32 EKX48877.1 - 1.1e-31 108.3 6.3 1.6e-06 28.7 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Prp19 PF08606.11 EKX48877.1 - 5e-29 100.1 0.5 9e-29 99.3 0.5 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 EKX48877.1 - 2.1e-15 56.8 0.3 0.0013 18.9 0.0 4.4 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EKX48877.1 - 4.5e-10 39.7 1.1 0.015 15.2 0.3 3.7 3 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EKX48877.1 - 7.6e-05 21.6 0.1 0.22 10.1 0.1 2.5 2 0 0 2 2 2 2 Nucleoporin Nup120/160 HPS3_N PF14761.6 EKX48877.1 - 0.00036 20.1 0.2 0.7 9.4 0.0 3.0 2 1 1 3 3 3 2 Hermansky-Pudlak syndrome 3 MMR_HSR1_C PF08438.10 EKX48877.1 - 0.004 17.7 0.6 0.054 14.1 0.1 2.4 2 0 0 2 2 2 1 GTPase of unknown function C-terminal Ge1_WD40 PF16529.5 EKX48877.1 - 0.006 15.6 1.9 0.79 8.6 0.0 3.3 2 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein U-box PF04564.15 EKX48877.1 - 0.019 15.1 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 U-box domain WD40_like PF17005.5 EKX48877.1 - 0.031 13.6 0.1 0.49 9.7 0.0 2.3 1 1 1 2 2 2 0 WD40-like domain YcgR PF07317.12 EKX48877.1 - 0.044 13.7 0.1 4.9 7.1 0.1 2.6 2 0 0 2 2 2 0 Flagellar regulator YcgR WLM PF08325.10 EKX48878.1 - 7.4e-50 169.7 0.3 9.5e-50 169.3 0.3 1.1 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 EKX48878.1 - 0.036 14.1 0.2 0.069 13.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 PDZ_6 PF17820.1 EKX48879.1 - 5.1e-06 26.2 1.1 2.2e-05 24.2 0.1 2.4 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX48879.1 - 0.00013 22.2 0.8 0.00051 20.3 0.8 2.1 1 1 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX48879.1 - 0.00066 20.0 0.2 0.0018 18.6 0.2 1.8 1 0 0 1 1 1 1 PDZ domain Spt20 PF12090.8 EKX48880.1 - 3.5e-06 26.8 2.8 3.5e-06 26.8 2.8 2.1 2 0 0 2 2 2 1 Spt20 family Pex14_N PF04695.13 EKX48880.1 - 0.02 15.6 5.3 0.02 15.6 5.3 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 EKX48880.1 - 0.51 10.3 25.8 0.13 12.3 13.6 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Herpes_DNAp_acc PF04929.12 EKX48880.1 - 1.7 7.6 13.8 0.062 12.3 3.8 2.1 2 0 0 2 2 2 0 Herpes DNA replication accessory factor Suf PF05843.14 EKX48880.1 - 3.2 7.6 13.0 6 6.8 3.9 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Pkinase PF00069.25 EKX48881.1 - 4.8e-25 88.4 0.2 1e-17 64.4 0.0 2.2 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EKX48881.1 - 2.1e-05 23.9 0.6 0.084 12.1 0.0 2.8 3 1 0 3 3 3 2 Protein tyrosine kinase Cyclin PF08613.11 EKX48883.1 - 3.1e-26 92.7 0.1 4e-26 92.3 0.1 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EKX48883.1 - 2.5e-05 24.0 0.1 3e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain MRF_C1 PF13887.6 EKX48883.1 - 0.042 13.0 0.1 0.097 11.8 0.1 1.6 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 Guanylate_cyc PF00211.20 EKX48884.1 - 7.4e-22 77.8 0.0 7.8e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain AP4E_app_platf PF14807.6 EKX48884.1 - 0.046 14.1 0.0 0.064 13.6 0.0 1.3 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Guanylate_cyc PF00211.20 EKX48885.1 - 2.9e-27 95.5 0.0 3.2e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain BRCT PF00533.26 EKX48886.1 - 3.5e-06 27.3 0.0 4.7e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EKX48886.1 - 0.00054 20.3 0.0 0.00077 19.8 0.0 1.2 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EKX48886.1 - 0.0024 17.8 0.0 0.004 17.1 0.0 1.3 1 0 0 1 1 1 1 twin BRCT domain BRCT_3 PF18428.1 EKX48886.1 - 0.024 14.7 0.0 0.034 14.2 0.0 1.2 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Hexokinase_2 PF03727.16 EKX48886.1 - 0.068 12.6 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Hexokinase T3SS_needle_E PF08988.10 EKX48887.1 - 0.76 10.0 3.3 1.4 9.1 0.2 3.1 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle DCP2 PF05026.13 EKX48888.1 - 6e-21 74.6 0.9 1.1e-20 73.7 0.9 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 EKX48888.1 - 8.7e-15 54.9 0.0 1.5e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain CSD PF00313.22 EKX48889.1 - 1.5e-08 34.4 0.0 2.4e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain PI-PLC-C1 PF16670.5 EKX48889.1 - 0.2 10.7 0.0 0.27 10.3 0.0 1.1 1 0 0 1 1 1 0 Phosphoinositide phospholipase C, Ca2+-dependent DHHC PF01529.20 EKX48890.1 - 6.8e-19 68.3 15.8 4.8e-18 65.5 15.9 2.0 1 1 0 1 1 1 1 DHHC palmitoyltransferase Nuc_sug_transp PF04142.15 EKX48891.1 - 9.1e-23 80.9 13.9 1.1e-22 80.6 13.9 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter UPF0093 PF03653.13 EKX48891.1 - 0.16 12.2 3.3 0.32 11.2 0.0 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0093) Adeno_100 PF02438.16 EKX48891.1 - 0.16 10.1 0.0 0.21 9.7 0.0 1.1 1 0 0 1 1 1 0 Late 100kD protein Pkinase PF00069.25 EKX48893.1 - 2.8e-33 115.4 0.0 4.3e-31 108.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX48893.1 - 5e-29 101.4 0.1 1.1e-17 64.2 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX48893.1 - 0.031 13.0 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EKX48893.1 - 0.033 14.1 1.2 0.055 13.4 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Per1 PF04080.13 EKX48893.1 - 0.11 12.2 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 Per1-like family Ion_trans PF00520.31 EKX48897.1 - 9.6e-75 251.0 11.9 1.3e-41 142.4 1.0 3.2 3 0 0 3 3 3 3 Ion transport protein TnpV PF14198.6 EKX48898.1 - 0.082 12.9 1.3 0.14 12.2 1.3 1.3 1 0 0 1 1 1 0 Transposon-encoded protein TnpV DUF58 PF01882.18 EKX48898.1 - 0.18 12.1 0.4 0.45 10.8 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF58 Costars PF14705.6 EKX48899.1 - 1e-25 89.7 0.1 1.1e-25 89.6 0.1 1.0 1 0 0 1 1 1 1 Costars Myb_DNA-binding PF00249.31 EKX48900.1 - 9.9e-32 108.9 1.7 2.6e-15 56.4 0.1 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX48900.1 - 6.5e-24 83.9 0.1 6.5e-15 55.1 0.0 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EKX48900.1 - 0.00016 21.5 0.0 0.13 12.1 0.0 2.4 1 1 1 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EKX48900.1 - 0.0035 17.7 4.3 0.94 9.9 0.8 3.1 2 2 0 2 2 2 2 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 EKX48900.1 - 0.0037 17.3 0.0 3.6 7.6 0.0 2.4 2 1 1 3 3 3 2 SLIDE SCP-1 PF05483.12 EKX48900.1 - 0.025 12.6 0.2 0.03 12.3 0.2 1.0 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) Rap1_C PF11626.8 EKX48900.1 - 0.084 13.0 0.4 0.43 10.7 0.4 2.1 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain UAA PF08449.11 EKX48901.1 - 1.7e-40 139.2 24.3 2e-40 138.9 24.3 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EKX48901.1 - 0.00024 21.3 27.0 0.00031 20.9 9.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF373 PF04123.13 EKX48901.1 - 0.0063 16.0 5.5 0.0063 16.0 5.5 2.3 1 1 0 2 2 2 1 Domain of unknown function (DUF373) Pacifastin_I PF05375.13 EKX48902.1 - 0.28 11.0 9.5 0.76 9.6 4.6 2.4 2 0 0 2 2 2 0 Pacifastin inhibitor (LCMII) TPR_1 PF00515.28 EKX48903.1 - 0.11 12.3 1.0 3 7.8 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EKX48903.1 - 0.12 12.6 1.0 16 5.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat RhoGEF PF00621.20 EKX48904.1 - 1.2e-27 97.3 3.8 1.4e-27 97.1 3.8 1.1 1 0 0 1 1 1 1 RhoGEF domain Hist_deacetyl PF00850.19 EKX48905.1 - 1e-81 274.8 0.1 1.5e-81 274.3 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DUF3464 PF11947.8 EKX48906.1 - 2.6 7.8 8.4 3 7.6 8.4 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CobT PF06213.12 EKX48906.1 - 3.4 7.0 29.7 3.5 7.0 29.7 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mpp10 PF04006.12 EKX48906.1 - 3.4 6.0 31.9 3.6 5.9 31.9 1.0 1 0 0 1 1 1 0 Mpp10 protein DNA_pol_phi PF04931.13 EKX48906.1 - 5.2 5.0 40.6 6 4.8 40.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_Rpc4 PF05132.14 EKX48906.1 - 5.9 7.3 13.8 6.5 7.2 13.8 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 SURF2 PF05477.11 EKX48906.1 - 6.3 6.4 17.7 7.6 6.2 17.7 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF2457 PF10446.9 EKX48906.1 - 7.2 5.6 38.4 7.1 5.7 38.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) bZIP_2 PF07716.15 EKX48907.1 - 9.1e-05 22.5 10.7 9.1e-05 22.5 10.7 2.7 3 0 0 3 3 3 1 Basic region leucine zipper PAH PF02671.21 EKX48907.1 - 0.0016 18.5 2.9 0.0038 17.3 2.9 1.7 1 0 0 1 1 1 1 Paired amphipathic helix repeat bZIP_1 PF00170.21 EKX48907.1 - 0.0024 17.9 9.6 0.0024 17.9 9.6 2.9 4 0 0 4 4 4 1 bZIP transcription factor Mto2_bdg PF12808.7 EKX48907.1 - 0.85 10.0 14.9 0.3 11.4 8.7 2.6 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region WWE PF02825.20 EKX48908.1 - 1.1e-21 77.2 2.9 4.7e-08 33.5 0.1 5.6 4 1 0 4 4 4 3 WWE domain Lipase_3 PF01764.25 EKX48908.1 - 1.6e-16 60.4 0.0 3.4e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Ras PF00071.22 EKX48909.1 - 3.2e-59 199.2 0.1 3.8e-59 198.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EKX48909.1 - 1.2e-36 125.5 0.1 1.9e-36 124.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EKX48909.1 - 1.4e-15 57.2 0.0 1.7e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EKX48909.1 - 9.8e-05 21.8 0.1 0.00012 21.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EKX48909.1 - 0.0001 22.4 0.0 0.00018 21.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EKX48909.1 - 0.00015 21.3 0.0 0.00022 20.7 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EKX48909.1 - 0.00052 19.6 0.0 0.002 17.7 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EKX48909.1 - 0.0077 16.1 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase TniB PF05621.11 EKX48909.1 - 0.016 14.6 0.0 0.2 11.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 EKX48909.1 - 0.047 13.2 0.0 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region GNT-I PF03071.15 EKX48910.1 - 1.7e-15 56.7 0.4 1.9e-15 56.6 0.4 1.0 1 0 0 1 1 1 1 GNT-I family Glyco_transf_41 PF13844.6 EKX48911.1 - 3e-20 72.1 0.0 1.5e-15 56.7 0.0 3.0 2 1 0 3 3 3 2 Glycosyl transferase family 41 TPR_19 PF14559.6 EKX48911.1 - 0.00011 22.6 0.1 0.21 12.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX48911.1 - 0.005 17.6 0.5 0.34 11.8 0.0 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX48911.1 - 0.019 15.6 0.9 0.18 12.5 0.2 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat YceG_bac PF14266.6 EKX48911.1 - 0.094 11.6 0.1 0.13 11.1 0.1 1.1 1 0 0 1 1 1 0 Putative component of 'biosynthetic module' ANAPC3 PF12895.7 EKX48911.1 - 0.16 12.2 0.0 3.1 8.1 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Kinase-PPPase PF03618.14 EKX48913.1 - 1.1e-80 271.1 0.0 1.5e-80 270.7 0.0 1.1 1 0 0 1 1 1 1 Kinase/pyrophosphorylase NAD_binding_1 PF00175.21 EKX48914.1 - 6.4e-25 87.9 0.0 1.3e-24 86.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EKX48914.1 - 0.0014 18.9 0.0 0.0031 17.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Kinesin PF00225.23 EKX48915.1 - 3.5e-94 315.5 0.3 4.2e-94 315.2 0.3 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX48915.1 - 1.9e-31 109.0 0.2 5.3e-31 107.6 0.1 1.7 2 0 0 2 2 2 1 Microtubule binding SRP_TPR_like PF17004.5 EKX48916.1 - 0.06 13.4 0.2 0.21 11.6 0.1 1.9 1 1 0 1 1 1 0 Putative TPR-like repeat DUF2203 PF09969.9 EKX48916.1 - 0.29 11.8 4.4 0.21 12.3 2.6 1.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) YlqD PF11068.8 EKX48916.1 - 0.93 9.9 6.5 0.51 10.7 4.6 1.6 1 1 0 1 1 1 0 YlqD protein BST2 PF16716.5 EKX48916.1 - 3.3 8.4 5.8 2.5 8.8 1.0 2.6 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 LRR_6 PF13516.6 EKX48917.1 - 3.6e-05 23.5 0.1 0.00022 21.0 0.0 2.3 2 0 0 2 2 2 1 Leucine Rich repeat FBA_1 PF07734.13 EKX48917.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 F-box associated Hydrolase_4 PF12146.8 EKX48918.1 - 1.6e-10 40.6 0.2 0.00051 19.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 EKX48918.1 - 0.00021 21.0 0.0 0.00037 20.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 EKX48918.1 - 0.0015 18.2 0.1 0.34 10.5 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EKX48918.1 - 0.05 13.1 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family LSM PF01423.22 EKX48919.1 - 1.7e-22 78.8 0.1 2e-22 78.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 EKX48919.1 - 0.064 13.4 0.0 0.093 12.8 0.0 1.4 1 1 0 1 1 1 0 Scd6-like Sm domain SM-ATX PF14438.6 EKX48919.1 - 0.12 12.5 0.0 0.16 12.2 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF3999 PF13163.6 EKX48921.1 - 0.013 14.8 0.1 0.015 14.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3999) DUF1230 PF06799.11 EKX48922.1 - 1.1e-27 96.9 0.0 1.9e-18 66.9 0.0 2.2 2 0 0 2 2 2 2 Conserved in the green lineage and diatoms 27 Lipase_3 PF01764.25 EKX48923.1 - 7.8e-16 58.2 0.0 1.3e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EKX48923.1 - 6.8e-05 23.6 0.0 8.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EKX48923.1 - 0.0047 16.2 0.0 0.014 14.7 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EKX48923.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.14 EKX48923.1 - 0.014 14.9 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 EKX48923.1 - 0.024 14.4 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein YjeF_N PF03853.15 EKX48923.1 - 0.027 14.4 0.1 0.11 12.3 0.1 2.0 1 1 0 1 1 1 0 YjeF-related protein N-terminus PAF-AH_p_II PF03403.13 EKX48923.1 - 0.027 13.0 0.0 0.035 12.6 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF2974 PF11187.8 EKX48923.1 - 0.06 12.9 0.5 0.16 11.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 EKX48923.1 - 0.071 12.9 0.1 0.16 11.7 0.1 1.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 EKX48923.1 - 0.093 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Chlorophyllase PF07224.11 EKX48923.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase GFO_IDH_MocA PF01408.22 EKX48924.1 - 3.5e-07 31.1 0.0 8.1e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold UMPH-1 PF05822.12 EKX48924.1 - 1.4e-06 28.0 0.0 0.00036 20.1 0.0 2.3 2 0 0 2 2 2 2 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 EKX48924.1 - 0.0061 16.9 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4147 PF13660.6 EKX48924.1 - 0.057 12.9 0.1 2.4 7.6 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4147) NAD_binding_3 PF03447.16 EKX48924.1 - 0.082 13.6 0.2 0.23 12.1 0.2 1.8 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain PH PF00169.29 EKX48925.1 - 3.9e-18 65.9 1.6 2e-08 34.7 0.1 2.3 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 EKX48925.1 - 0.069 13.5 0.6 0.43 11.0 0.0 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain PH_17 PF18012.1 EKX48925.1 - 0.12 12.1 0.0 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 PH domain PH_11 PF15413.6 EKX48925.1 - 0.7 10.3 7.2 21 5.6 0.7 4.1 2 2 0 2 2 2 0 Pleckstrin homology domain FBPase PF00316.20 EKX48926.1 - 1.1e-32 113.0 0.2 1.6e-32 112.5 0.2 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain zf-C2HC_2 PF13913.6 EKX48927.1 - 0.034 14.0 0.2 0.11 12.5 0.2 1.8 1 0 0 1 1 1 0 zinc-finger of a C2HC-type CCDC24 PF15669.5 EKX48927.1 - 4.2 7.2 7.0 5.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Rrn6 PF10214.9 EKX48927.1 - 5.1 5.5 9.9 3.4 6.0 6.6 2.0 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor zf-C3HC4_2 PF13923.6 EKX48928.1 - 2.9e-08 33.4 7.0 1.1e-07 31.6 7.0 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX48928.1 - 1.6e-07 31.5 5.8 1.6e-07 31.5 5.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 EKX48928.1 - 1.8e-07 30.8 1.1 4.9e-07 29.4 1.1 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 EKX48928.1 - 1.4e-05 24.9 4.9 1.4e-05 24.9 4.9 2.1 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EKX48928.1 - 6.3e-05 22.9 4.0 0.00011 22.2 2.3 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EKX48928.1 - 0.00015 21.6 5.8 0.00015 21.6 5.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX48928.1 - 0.00023 21.4 4.1 0.00023 21.4 4.1 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EKX48928.1 - 0.001 19.1 1.8 0.001 19.1 1.8 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EKX48928.1 - 0.019 14.8 6.8 0.019 14.8 6.8 2.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EKX48928.1 - 0.078 13.1 9.2 0.15 12.2 7.9 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 EKX48928.1 - 0.1 12.4 2.6 0.26 11.1 2.6 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-HC5HC2H_2 PF13832.6 EKX48928.1 - 0.54 10.4 9.5 0.038 14.1 2.4 2.3 1 1 1 2 2 2 0 PHD-zinc-finger like domain Prok-RING_1 PF14446.6 EKX48928.1 - 0.72 9.8 8.3 0.92 9.5 4.0 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.6 EKX48928.1 - 2.5 8.4 9.9 0.13 12.5 2.3 2.5 1 1 1 2 2 2 0 PHD-like zinc-binding domain WD40 PF00400.32 EKX48929.1 - 1.5e-30 104.7 26.0 2.1e-09 37.9 1.8 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX48929.1 - 1.7e-08 34.6 0.4 0.19 12.1 0.0 3.5 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX48929.1 - 0.0093 15.0 0.5 0.46 9.4 0.0 2.7 1 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EKX48929.1 - 0.089 11.3 0.1 0.4 9.2 0.0 1.8 1 1 0 2 2 2 0 Cytochrome D1 heme domain eIF2A PF08662.11 EKX48929.1 - 0.13 12.1 0.0 1.8 8.4 0.0 2.2 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF563 PF04577.14 EKX48930.1 - 3.4e-07 30.6 0.1 1.5e-06 28.5 0.1 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Glyco_trans_1_2 PF13524.6 EKX48930.1 - 9.4e-07 29.1 0.0 2.3e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Na_H_Exchanger PF00999.21 EKX48931.1 - 2.7e-17 62.7 41.0 4.2e-17 62.0 41.0 1.3 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family EpuA PF11772.8 EKX48931.1 - 9.6 6.0 12.5 38 4.1 12.5 2.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta LRR_8 PF13855.6 EKX48932.1 - 3.5e-18 65.1 19.9 1.8e-09 37.3 3.9 4.7 2 2 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 EKX48932.1 - 4.3e-11 42.9 16.9 0.0004 20.7 0.4 4.9 2 2 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX48932.1 - 5.4e-10 38.4 7.4 0.052 14.1 0.1 6.1 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.6 EKX48932.1 - 0.055 13.6 8.8 1.2 9.4 0.1 4.9 6 0 0 6 6 6 0 Leucine Rich repeat LRR_9 PF14580.6 EKX48932.1 - 0.12 11.9 2.2 1.1 8.8 0.2 2.2 1 1 0 2 2 2 0 Leucine-rich repeat FA_hydroxylase PF04116.13 EKX48933.1 - 7.4e-20 71.6 14.5 7.4e-20 71.6 14.5 1.6 1 1 0 1 1 1 1 Fatty acid hydroxylase superfamily Topo-VIb_trans PF09239.11 EKX48933.1 - 0.047 13.5 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 Topoisomerase VI B subunit, transducer Kelch_5 PF13854.6 EKX48934.1 - 3.2e-28 97.2 33.2 0.00013 21.8 0.1 14.0 15 0 0 15 15 15 8 Kelch motif Kelch_3 PF13415.6 EKX48934.1 - 3.8e-27 94.0 60.4 0.0039 17.4 0.3 17.1 18 0 0 18 18 18 9 Galactose oxidase, central domain Kelch_4 PF13418.6 EKX48934.1 - 5.7e-27 93.5 41.9 0.00017 21.5 0.4 14.9 15 0 0 15 15 15 7 Galactose oxidase, central domain Filamin PF00630.19 EKX48934.1 - 1e-19 71.3 0.0 5.3e-10 40.0 0.0 3.7 3 0 0 3 3 3 2 Filamin/ABP280 repeat Kelch_6 PF13964.6 EKX48934.1 - 2.9e-14 52.7 33.3 0.012 15.9 0.3 12.7 15 0 0 15 15 15 4 Kelch motif Kelch_1 PF01344.25 EKX48934.1 - 6.8e-11 41.6 24.8 0.037 13.6 0.5 10.9 11 0 0 11 11 11 3 Kelch motif Invasin_D3 PF09134.10 EKX48934.1 - 3.4e-05 24.1 1.7 0.38 11.1 0.1 4.2 4 0 0 4 4 4 2 Invasin, domain 3 Snapin_Pallidin PF14712.6 EKX48935.1 - 2.8e-06 27.6 0.4 2.8e-06 27.6 0.4 1.8 2 0 0 2 2 2 1 Snapin/Pallidin KxDL PF10241.9 EKX48935.1 - 0.00043 20.5 0.5 0.00043 20.5 0.5 1.8 1 1 1 2 2 2 1 Uncharacterized conserved protein ORF6C PF10552.9 EKX48935.1 - 0.0099 16.0 1.5 0.012 15.7 1.5 1.1 1 0 0 1 1 1 1 ORF6C domain Spectrin PF00435.21 EKX48935.1 - 0.012 16.0 2.0 0.013 15.9 2.0 1.1 1 0 0 1 1 1 0 Spectrin repeat OmpH PF03938.14 EKX48935.1 - 0.078 13.3 8.3 0.086 13.2 8.3 1.0 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TMPIT PF07851.13 EKX48935.1 - 0.23 10.7 3.8 0.24 10.6 3.8 1.0 1 0 0 1 1 1 0 TMPIT-like protein 60KD_IMP PF02096.20 EKX48935.1 - 0.24 11.3 1.6 0.3 11.0 1.6 1.1 1 0 0 1 1 1 0 60Kd inner membrane protein PIEZO PF15917.5 EKX48935.1 - 0.29 10.6 4.2 0.32 10.5 4.2 1.0 1 0 0 1 1 1 0 Piezo EMC3_TMCO1 PF01956.16 EKX48935.1 - 0.43 10.3 4.3 0.5 10.1 4.3 1.0 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF2838 PF10998.8 EKX48936.1 - 4e-36 123.6 6.3 4e-36 123.6 6.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) HMW1C_N PF18071.1 EKX48936.1 - 0.099 12.4 0.3 0.16 11.8 0.3 1.3 1 0 0 1 1 1 0 HMW1C N-terminal DUF1118 PF06549.12 EKX48937.1 - 0.11 12.8 0.1 0.23 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1118) PAS_9 PF13426.7 EKX48938.1 - 2e-08 34.4 0.0 4.7e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 PAS domain HLH PF00010.26 EKX48938.1 - 8.3e-07 28.9 0.3 1.3e-06 28.2 0.3 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PAS_4 PF08448.10 EKX48938.1 - 1.3e-06 28.6 0.0 2.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EKX48938.1 - 2.1e-06 27.6 0.0 5.5e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EKX48938.1 - 2.3e-06 27.6 0.3 5.1e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 EKX48938.1 - 0.00059 20.1 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 PAS fold Borrelia_P83 PF05262.11 EKX48938.1 - 0.043 12.3 2.2 0.046 12.2 2.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF573 PF04504.14 EKX48939.1 - 0.056 14.1 0.3 0.19 12.4 0.3 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF573 Dicty_REP PF05086.12 EKX48941.1 - 1.9 6.4 4.8 2.1 6.2 4.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein His_Phos_1 PF00300.22 EKX48942.1 - 2.4e-23 82.8 0.1 2.5e-13 50.2 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Kinesin PF00225.23 EKX48945.1 - 8.3e-93 310.9 0.0 1.3e-92 310.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX48945.1 - 1.4e-16 60.8 0.0 3e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding DUF3584 PF12128.8 EKX48946.1 - 0.019 12.5 1.5 0.023 12.2 1.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) LTXXQ PF07813.12 EKX48946.1 - 0.051 14.3 2.4 0.12 13.2 2.4 1.6 1 0 0 1 1 1 0 LTXXQ motif family protein ARA70 PF12489.8 EKX48946.1 - 0.25 11.5 1.7 0.25 11.6 0.6 1.6 2 0 0 2 2 2 0 Nuclear coactivator tRNA-synt_2b PF00587.25 EKX48948.1 - 2.2e-37 128.7 0.0 5.1e-37 127.6 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EKX48948.1 - 7.2e-21 74.5 4.7 7.2e-21 74.5 4.7 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain TerB_C PF15615.6 EKX48948.1 - 0.098 13.0 1.4 0.21 11.8 1.4 1.6 1 0 0 1 1 1 0 TerB-C domain DUF4223 PF13978.6 EKX48948.1 - 0.2 11.6 0.5 0.47 10.4 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) TMF_TATA_bd PF12325.8 EKX48948.1 - 0.25 11.6 3.8 0.69 10.1 3.8 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding BLOC1_2 PF10046.9 EKX48948.1 - 3 8.2 5.4 2.2 8.6 3.1 1.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 tRNA-synt_2b PF00587.25 EKX48949.1 - 1.4e-37 129.4 0.0 2.6e-37 128.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EKX48949.1 - 1.4e-07 31.7 0.5 1.4e-07 31.7 0.5 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain RCC1 PF00415.18 EKX48952.1 - 4.4e-57 190.5 24.1 4.5e-12 46.4 0.1 8.5 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX48952.1 - 2.2e-40 135.7 38.4 1.7e-09 37.3 1.1 7.5 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Kelch_4 PF13418.6 EKX48952.1 - 0.37 10.8 2.2 2.3 8.3 0.7 2.6 2 0 0 2 2 2 0 Galactose oxidase, central domain Ribosomal_S13_N PF08069.12 EKX48954.1 - 3.5e-29 100.6 1.4 6.3e-29 99.8 1.4 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EKX48954.1 - 3.3e-13 49.6 0.1 5.4e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 Gly_rich PF12810.7 EKX48955.1 - 0.041 13.8 11.1 1.8 8.4 12.0 2.6 1 1 1 2 2 2 0 Glycine rich protein FHA PF00498.26 EKX48957.1 - 4.6e-15 55.7 0.1 1.3e-14 54.3 0.1 1.8 1 0 0 1 1 1 1 FHA domain YfdX PF10938.8 EKX48957.1 - 0.03 14.2 1.4 0.24 11.3 0.2 2.3 2 0 0 2 2 2 0 YfdX protein FAM176 PF14851.6 EKX48958.1 - 0.07 12.8 1.3 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 FAM176 family ubiquitin PF00240.23 EKX48959.1 - 3e-19 68.5 0.1 5.5e-19 67.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family ZZ PF00569.17 EKX48959.1 - 1.3e-13 50.5 4.8 2.3e-13 49.7 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Rad60-SLD PF11976.8 EKX48959.1 - 6.6e-08 32.3 0.0 1.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EKX48959.1 - 0.0004 20.5 0.0 0.00091 19.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EKX48959.1 - 0.017 15.0 0.0 0.08 12.9 0.0 2.0 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 EKX48959.1 - 0.017 15.5 0.0 0.037 14.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain Jnk-SapK_ap_N PF09744.9 EKX48960.1 - 0.00051 20.3 14.8 0.00058 20.1 14.8 1.2 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Rab5-bind PF09311.11 EKX48960.1 - 0.0027 17.1 13.1 0.0038 16.7 13.1 1.2 1 0 0 1 1 1 1 Rabaptin-like protein DUF641 PF04859.12 EKX48960.1 - 0.0034 17.7 13.6 0.011 16.1 12.8 1.9 1 1 0 1 1 1 1 Plant protein of unknown function (DUF641) Golgin_A5 PF09787.9 EKX48960.1 - 0.0059 16.1 16.7 0.0065 16.0 16.7 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 5 ERM PF00769.19 EKX48960.1 - 0.017 14.9 18.3 0.021 14.7 18.3 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family PspA_IM30 PF04012.12 EKX48960.1 - 0.025 14.1 13.2 0.035 13.7 12.1 1.6 1 1 1 2 2 2 0 PspA/IM30 family PCRF PF03462.18 EKX48960.1 - 0.027 14.3 9.3 0.035 14.0 9.3 1.1 1 0 0 1 1 1 0 PCRF domain Filament PF00038.21 EKX48960.1 - 0.079 12.5 15.1 0.089 12.4 12.6 1.8 1 1 1 2 2 2 0 Intermediate filament protein ApoO PF09769.9 EKX48960.1 - 0.095 12.7 1.8 0.18 11.8 1.8 1.5 1 1 0 1 1 1 0 Apolipoprotein O Spc7 PF08317.11 EKX48960.1 - 0.11 11.3 15.6 0.14 11.1 15.6 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein SPX PF03105.19 EKX48960.1 - 0.21 11.5 8.7 0.24 11.3 8.7 1.0 1 0 0 1 1 1 0 SPX domain Exonuc_VII_L PF02601.15 EKX48960.1 - 0.31 10.6 8.4 0.34 10.4 8.4 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sulfatase_C PF14707.6 EKX48960.1 - 0.33 11.7 1.8 0.49 11.1 1.8 1.5 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase COG2 PF06148.11 EKX48960.1 - 0.63 10.1 9.4 0.2 11.8 5.2 1.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 eIF-4B PF06273.11 EKX48960.1 - 0.68 8.9 9.7 0.71 8.9 9.7 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B ZYG-11_interact PF05884.12 EKX48960.1 - 0.92 8.9 2.6 1 8.7 2.6 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 Y2_Tnp PF04986.13 EKX48960.1 - 1 9.4 3.8 0.53 10.3 1.2 1.6 1 1 1 2 2 2 0 Putative transposase Csm1_N PF18504.1 EKX48960.1 - 1.3 9.4 14.9 2 8.8 2.5 2.7 1 1 2 3 3 3 0 Csm1 N-terminal domain DUF1664 PF07889.12 EKX48960.1 - 1.3 9.0 7.2 1.4 9.0 6.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 EKX48960.1 - 1.6 8.8 15.3 1.8 8.6 15.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 EKX48960.1 - 1.6 8.0 6.8 1.9 7.8 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LRS4 PF10422.9 EKX48960.1 - 1.7 8.2 10.8 2 7.9 10.8 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Fungal_TACC PF12709.7 EKX48960.1 - 1.7 9.1 14.6 0.22 12.0 2.7 3.0 1 1 2 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins TMPIT PF07851.13 EKX48960.1 - 1.9 7.7 8.9 2.3 7.4 8.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.19 EKX48960.1 - 2.4 6.0 9.8 2.7 5.8 9.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family G-gamma PF00631.22 EKX48960.1 - 2.6 8.1 7.2 2.5 8.2 1.1 2.3 2 0 0 2 2 2 0 GGL domain BST2 PF16716.5 EKX48960.1 - 3.3 8.3 11.5 7.7 7.2 2.7 2.3 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Atg14 PF10186.9 EKX48960.1 - 5.9 5.9 11.2 7.4 5.6 11.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FmiP_Thoc5 PF09766.9 EKX48960.1 - 6 6.1 14.3 15 4.8 14.3 1.6 1 1 0 1 1 1 0 Fms-interacting protein/Thoc5 Zn_clus PF00172.18 EKX48961.1 - 2.9e-11 43.3 32.7 2.6e-06 27.4 10.6 2.2 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain CxC2 PF18803.1 EKX48962.1 - 0.11 12.6 0.2 0.18 11.9 0.2 1.4 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases HIT PF01230.23 EKX48963.1 - 1.3e-28 99.6 0.0 1.4e-28 99.5 0.0 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EKX48963.1 - 6.3e-17 62.1 0.0 7.2e-17 61.9 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CDH PF02611.15 EKX48963.1 - 0.1 12.2 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase LRR_6 PF13516.6 EKX48964.1 - 7.2e-18 63.1 12.7 0.00046 20.0 0.2 6.1 6 0 0 6 6 6 5 Leucine Rich repeat LRR_4 PF12799.7 EKX48964.1 - 0.00028 21.2 6.8 0.87 10.1 0.3 4.4 2 1 3 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX48964.1 - 0.00072 19.3 12.2 0.38 10.5 3.0 4.6 2 1 2 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 EKX48964.1 - 0.09 13.4 8.2 7.7 7.5 0.0 5.4 4 2 0 4 4 4 0 Leucine Rich Repeat Ank_2 PF12796.7 EKX48965.1 - 8.6e-10 39.1 0.1 2.2e-09 37.8 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX48965.1 - 1e-09 38.7 0.1 1.8e-07 31.5 0.0 2.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX48965.1 - 2.4e-09 36.7 0.1 0.13 12.9 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EKX48965.1 - 2.2e-05 24.6 0.1 0.032 14.6 0.1 2.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX48965.1 - 0.00021 21.6 0.0 1.1 9.9 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat DUF89 PF01937.19 EKX48966.1 - 9.7e-63 212.2 0.0 1.1e-62 212.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF2408 PF10303.9 EKX48967.1 - 0.015 15.9 0.8 0.028 15.0 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) RNA_GG_bind PF10258.9 EKX48967.1 - 0.066 13.3 0.2 0.19 11.8 0.1 1.9 1 1 0 1 1 1 0 PHAX RNA-binding domain DUF3408 PF11888.8 EKX48967.1 - 1.7 8.8 9.0 0.17 12.0 2.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) IQ PF00612.27 EKX48968.1 - 0.34 10.8 3.2 0.97 9.4 3.2 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif Aldose_epim PF01263.20 EKX48969.1 - 1.8e-44 152.3 0.0 2.4e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase UBA_4 PF14555.6 EKX48969.1 - 0.059 13.2 0.0 9.1 6.2 0.0 2.4 2 0 0 2 2 2 0 UBA-like domain Ion_trans PF00520.31 EKX48970.1 - 1.1e-34 119.7 21.5 1.7e-34 119.1 21.5 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EKX48970.1 - 4.7e-06 25.5 13.6 4.3e-05 22.4 13.7 2.0 1 1 1 2 2 2 2 Polycystin cation channel RL PF17797.1 EKX48970.1 - 0.059 13.3 0.1 0.21 11.6 0.1 1.9 1 0 0 1 1 1 0 RL domain TB2_DP1_HVA22 PF03134.19 EKX48970.1 - 0.36 10.8 3.3 5.9 6.9 1.2 2.6 2 0 0 2 2 2 0 TB2/DP1, HVA22 family BCCT PF02028.17 EKX48971.1 - 2.1e-140 468.4 33.3 2.3e-115 385.8 31.4 2.2 2 0 0 2 2 2 2 BCCT, betaine/carnitine/choline family transporter PLAC8 PF04749.17 EKX48971.1 - 7.9e-05 23.6 1.6 0.00046 21.1 0.0 3.1 3 0 0 3 3 3 1 PLAC8 family FHA PF00498.26 EKX48972.1 - 4.8e-18 65.3 0.3 4.7e-17 62.1 0.1 1.9 1 1 1 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EKX48972.1 - 1.3e-10 41.4 0.1 1.5e-10 41.2 0.1 1.1 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Trp_syntA PF00290.20 EKX48972.1 - 0.083 11.7 0.0 0.097 11.5 0.0 1.1 1 0 0 1 1 1 0 Tryptophan synthase alpha chain DUF3626 PF12294.8 EKX48972.1 - 0.099 11.7 0.1 0.12 11.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) Lyase_1 PF00206.20 EKX48973.1 - 3.6e-95 318.9 0.0 5.2e-95 318.4 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 EKX48973.1 - 3e-20 72.7 0.0 7.3e-20 71.5 0.0 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal TB2_DP1_HVA22 PF03134.19 EKX48974.1 - 2.5e-18 65.8 1.6 5.7e-18 64.6 1.6 1.6 1 0 0 1 1 1 1 TB2/DP1, HVA22 family C2 PF00168.30 EKX48974.1 - 0.002 18.4 0.0 1.4 9.2 0.0 2.4 2 0 0 2 2 2 2 C2 domain EOS1 PF12326.8 EKX48974.1 - 0.15 12.0 3.9 0.3 11.0 3.2 1.9 1 1 1 2 2 2 0 N-glycosylation protein Spc7 PF08317.11 EKX48975.1 - 0.015 14.2 5.5 0.81 8.5 0.6 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.12 EKX48975.1 - 0.032 14.3 0.3 1.7 8.7 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.11 EKX48975.1 - 0.078 13.5 1.3 3 8.5 0.2 2.4 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Fez1 PF06818.15 EKX48975.1 - 0.098 13.1 9.9 0.53 10.7 1.8 2.3 1 1 1 2 2 2 0 Fez1 XhlA PF10779.9 EKX48975.1 - 0.2 11.9 3.4 9.9 6.4 0.0 2.6 3 0 0 3 3 3 0 Haemolysin XhlA GAS PF13851.6 EKX48975.1 - 0.53 9.6 5.2 0.78 9.1 0.9 2.5 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding TMPIT PF07851.13 EKX48975.1 - 1.5 8.0 5.2 9.8 5.3 0.5 2.1 2 0 0 2 2 2 0 TMPIT-like protein APC_u14 PF16635.5 EKX48976.1 - 0.1 13.1 0.8 0.18 12.3 0.5 1.5 1 1 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr HMG_box_2 PF09011.10 EKX48976.1 - 0.17 12.5 4.8 1.1 9.9 1.6 2.3 1 1 1 2 2 2 0 HMG-box domain Kelch_3 PF13415.6 EKX48977.1 - 4.4e-16 58.7 2.8 1.1e-07 32.0 0.1 3.0 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_4 PF13418.6 EKX48977.1 - 8e-15 54.6 7.0 1.5e-06 28.1 0.2 3.1 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EKX48977.1 - 3.3e-14 52.5 5.6 6.4e-08 32.4 0.1 3.1 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 EKX48977.1 - 1.8e-11 43.9 2.9 0.00061 20.0 0.1 3.1 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 EKX48977.1 - 1.3e-06 28.1 5.7 0.048 13.7 0.1 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 EKX48977.1 - 5.9e-06 25.8 1.1 0.29 10.8 0.1 3.2 3 0 0 3 3 3 3 Kelch motif LRR_6 PF13516.6 EKX48978.1 - 1.9e-08 33.7 18.6 0.12 12.5 0.1 7.6 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.7 EKX48978.1 - 8.3e-05 22.9 18.2 0.0059 17.0 0.2 6.6 7 1 1 8 8 8 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX48978.1 - 0.017 14.9 20.6 0.64 9.8 1.4 6.1 4 2 3 7 7 7 0 Leucine rich repeat LRR_1 PF00560.33 EKX48978.1 - 0.021 15.3 22.4 17 6.4 0.4 8.0 8 2 0 8 8 8 0 Leucine Rich Repeat LRR_9 PF14580.6 EKX48978.1 - 0.056 12.9 0.5 0.16 11.5 0.0 1.9 2 1 0 2 2 2 0 Leucine-rich repeat DELLA PF12041.8 EKX48978.1 - 0.098 12.6 0.0 0.36 10.8 0.0 1.9 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal LRR_4 PF12799.7 EKX48979.1 - 0.0036 17.7 0.3 0.24 11.9 0.0 2.4 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX48979.1 - 0.0059 16.4 0.3 0.23 11.2 0.0 2.4 2 0 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.6 EKX48979.1 - 0.016 15.3 0.3 0.16 12.1 0.1 2.7 3 0 0 3 3 3 0 Leucine Rich repeat F-box-like PF12937.7 EKX48979.1 - 0.035 14.0 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 F-box-like LRR_1 PF00560.33 EKX48979.1 - 0.049 14.2 0.1 1.7 9.5 0.0 2.8 2 0 0 2 2 2 0 Leucine Rich Repeat AOX PF01786.17 EKX48980.1 - 1.9e-95 318.5 0.1 2.2e-95 318.3 0.1 1.0 1 0 0 1 1 1 1 Alternative oxidase AOX PF01786.17 EKX48981.1 - 1.9e-95 318.5 0.1 2.2e-95 318.3 0.1 1.0 1 0 0 1 1 1 1 Alternative oxidase 2-oxoacid_dh PF00198.23 EKX48982.1 - 6.5e-69 231.9 0.1 7.2e-69 231.8 0.1 1.0 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Pro_isomerase PF00160.21 EKX48983.1 - 2.9e-49 167.4 0.4 3.2e-49 167.2 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GHMP_kinases_N PF00288.26 EKX48984.1 - 4.4e-13 49.3 1.4 1e-12 48.0 1.4 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain DUF3206 PF11472.8 EKX48984.1 - 0.021 14.8 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) HHH_9 PF17674.1 EKX48985.1 - 7.1e-16 58.9 0.1 4.3e-14 53.2 0.1 2.5 1 1 0 1 1 1 1 HHH domain HHH_3 PF12836.7 EKX48985.1 - 1.4e-15 57.3 0.3 2.8e-14 53.1 0.1 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH PF00633.23 EKX48985.1 - 4.9e-05 23.0 0.0 0.00045 20.0 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif S1 PF00575.23 EKX48985.1 - 6.9e-05 23.1 4.7 0.00045 20.5 4.7 2.1 1 1 0 1 1 1 1 S1 RNA binding domain HHH_5 PF14520.6 EKX48985.1 - 0.0053 17.3 0.1 1.2 9.8 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_6 PF14579.6 EKX48985.1 - 0.031 14.5 0.0 0.084 13.1 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif CENP-B_N PF04218.13 EKX48985.1 - 0.056 13.1 0.0 0.7 9.6 0.0 2.2 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain RsgI_N PF12791.7 EKX48985.1 - 0.48 10.4 3.1 15 5.6 0.2 2.9 3 0 0 3 3 3 0 Anti-sigma factor N-terminus ABC_tran PF00005.27 EKX48986.1 - 0.012 16.2 0.0 0.092 13.3 0.0 2.5 2 0 0 2 2 2 0 ABC transporter RsgA_GTPase PF03193.16 EKX48986.1 - 0.054 13.4 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase NLE PF08154.12 EKX48986.1 - 0.057 14.0 0.5 4 8.0 0.1 3.0 2 0 0 2 2 2 0 NLE (NUC135) domain Uteroglobin PF01099.17 EKX48986.1 - 0.093 13.1 1.1 3.4 8.1 0.0 3.4 3 0 0 3 3 3 0 Uteroglobin family PIN_9 PF18477.1 EKX48986.1 - 0.096 13.0 0.4 31 4.9 0.2 3.0 2 0 0 2 2 2 0 PIN like domain Lysine_decarbox PF03641.14 EKX48986.1 - 0.11 12.6 0.0 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 Possible lysine decarboxylase CLASP_N PF12348.8 EKX48987.1 - 5.9e-40 137.2 7.2 3e-28 99.0 2.0 3.7 3 1 0 3 3 3 3 CLASP N terminal HEAT PF02985.22 EKX48987.1 - 3.9e-12 45.3 18.8 0.0021 18.1 0.2 8.9 8 0 0 8 8 8 2 HEAT repeat MMS19_C PF12460.8 EKX48987.1 - 1.6e-05 24.3 9.5 0.00041 19.6 0.2 4.0 4 0 0 4 4 4 2 RNAPII transcription regulator C-terminal Cnd1 PF12717.7 EKX48987.1 - 9.4e-05 22.5 6.6 1.1 9.3 0.1 4.5 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EKX48987.1 - 0.00014 22.3 21.6 0.0029 18.1 0.2 6.1 6 1 1 7 7 7 2 HEAT-like repeat Adaptin_N PF01602.20 EKX48987.1 - 0.00045 18.9 6.5 1.1 7.8 0.4 4.6 3 3 1 4 4 4 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 EKX48987.1 - 0.0015 19.1 0.2 0.12 13.0 0.0 3.3 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region Dopey_N PF04118.14 EKX48987.1 - 0.0092 15.1 0.5 0.38 9.8 0.0 3.0 2 1 0 2 2 2 1 Dopey, N-terminal HEAT_2 PF13646.6 EKX48987.1 - 0.05 14.0 19.8 0.75 10.2 0.1 5.8 7 1 1 8 8 8 0 HEAT repeats Ipi1_N PF12333.8 EKX48987.1 - 1.2 9.8 3.3 5.9 7.5 0.1 3.7 4 0 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation HTH_23 PF13384.6 EKX48988.1 - 0.00055 19.7 0.2 0.00091 19.0 0.2 1.4 1 0 0 1 1 1 1 Homeodomain-like domain Cro PF09048.10 EKX48988.1 - 0.0047 16.9 0.1 0.0074 16.3 0.1 1.4 1 0 0 1 1 1 1 Cro HTH_Crp_2 PF13545.6 EKX48988.1 - 0.021 14.8 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain CENP-B_N PF04218.13 EKX48988.1 - 0.027 14.1 0.4 0.88 9.3 0.4 2.6 1 1 1 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_3 PF01381.22 EKX48988.1 - 0.03 14.4 0.1 0.05 13.7 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix Sigma70_r4 PF04545.16 EKX48988.1 - 0.033 13.7 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 WGG PF10273.9 EKX48988.1 - 0.079 13.6 0.0 0.089 13.5 0.0 1.1 1 0 0 1 1 1 0 Pre-rRNA-processing protein TSR2 KorB PF08535.10 EKX48988.1 - 0.081 13.0 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 KorB domain FA_desaturase_2 PF03405.14 EKX48988.1 - 0.1 11.5 0.1 0.19 10.5 0.0 1.4 1 1 1 2 2 2 0 Fatty acid desaturase MarR_2 PF12802.7 EKX48988.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.6 EKX48989.1 - 0.00039 20.1 0.2 0.00057 19.6 0.2 1.3 1 0 0 1 1 1 1 Homeodomain-like domain Cro PF09048.10 EKX48989.1 - 0.0031 17.5 0.1 0.004 17.1 0.1 1.2 1 0 0 1 1 1 1 Cro HTH_Crp_2 PF13545.6 EKX48989.1 - 0.016 15.2 0.1 0.016 15.1 0.1 1.2 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_3 PF01381.22 EKX48989.1 - 0.021 14.8 0.1 0.034 14.2 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix Sigma70_r4 PF04545.16 EKX48989.1 - 0.024 14.2 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 KorB PF08535.10 EKX48989.1 - 0.058 13.4 0.0 0.071 13.2 0.0 1.1 1 0 0 1 1 1 0 KorB domain MarR_2 PF12802.7 EKX48989.1 - 0.072 13.0 0.0 0.085 12.8 0.0 1.1 1 0 0 1 1 1 0 MarR family FA_desaturase_2 PF03405.14 EKX48989.1 - 0.11 11.3 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Fatty acid desaturase HTH_23 PF13384.6 EKX48990.1 - 0.0022 17.7 0.1 0.0042 16.8 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain Cro PF09048.10 EKX48990.1 - 0.0095 16.0 0.3 0.016 15.2 0.3 1.3 1 0 0 1 1 1 1 Cro HTH_3 PF01381.22 EKX48990.1 - 0.015 15.4 0.1 0.026 14.6 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix FA_desaturase_2 PF03405.14 EKX48990.1 - 0.032 13.1 0.1 0.037 12.9 0.1 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Sigma70_r4 PF04545.16 EKX48990.1 - 0.052 13.1 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Crp_2 PF13545.6 EKX48990.1 - 0.075 13.0 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_23 PF13384.6 EKX48991.1 - 0.00039 20.1 0.2 0.00057 19.6 0.2 1.3 1 0 0 1 1 1 1 Homeodomain-like domain Cro PF09048.10 EKX48991.1 - 0.0031 17.5 0.1 0.004 17.1 0.1 1.2 1 0 0 1 1 1 1 Cro HTH_Crp_2 PF13545.6 EKX48991.1 - 0.016 15.2 0.1 0.016 15.1 0.1 1.2 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_3 PF01381.22 EKX48991.1 - 0.021 14.8 0.1 0.034 14.2 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix Sigma70_r4 PF04545.16 EKX48991.1 - 0.024 14.2 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 KorB PF08535.10 EKX48991.1 - 0.058 13.4 0.0 0.071 13.2 0.0 1.1 1 0 0 1 1 1 0 KorB domain MarR_2 PF12802.7 EKX48991.1 - 0.072 13.0 0.0 0.085 12.8 0.0 1.1 1 0 0 1 1 1 0 MarR family FA_desaturase_2 PF03405.14 EKX48991.1 - 0.11 11.3 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Fatty acid desaturase Ank_2 PF12796.7 EKX48993.1 - 6.2e-11 42.7 0.0 9.5e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX48993.1 - 2.4e-09 37.5 0.0 5.2e-07 30.1 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) CHB_HEX_C_1 PF13290.6 EKX48993.1 - 3.5e-09 36.5 0.3 6.9e-09 35.6 0.3 1.5 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain Ank_5 PF13857.6 EKX48993.1 - 3.2e-08 33.7 0.1 9.6e-08 32.2 0.1 1.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX48993.1 - 1.8e-07 30.9 0.0 0.00035 20.8 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Fn3_assoc PF13287.6 EKX48993.1 - 1.3e-06 28.4 0.2 3.6e-06 27.0 0.1 1.8 2 0 0 2 2 2 1 Fn3 associated Ank PF00023.30 EKX48993.1 - 5.3e-06 26.6 0.0 0.00058 20.2 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat PAS PF00989.25 EKX48994.1 - 0.021 14.8 0.7 0.083 12.9 0.5 2.1 1 1 0 1 1 1 0 PAS fold DUF2220 PF09983.9 EKX48994.1 - 0.094 12.1 0.2 0.094 12.1 0.2 2.1 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) KH_1 PF00013.29 EKX48995.1 - 7.2e-45 150.7 6.6 2.2e-14 53.0 0.0 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EKX48995.1 - 1.8e-11 43.7 1.4 0.00044 20.0 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EKX48995.1 - 2.8e-09 36.7 0.8 0.003 17.4 0.1 3.4 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 EKX48995.1 - 0.0025 17.8 4.8 0.32 11.1 0.2 3.3 3 0 0 3 3 3 2 NusA-like KH domain SLS PF14611.6 EKX48995.1 - 0.044 13.6 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator Yae1_N PF09811.9 EKX48997.1 - 0.0028 17.3 5.1 0.084 12.6 5.1 2.1 1 1 0 1 1 1 1 Essential protein Yae1, N terminal DUF2111 PF09884.9 EKX48997.1 - 0.15 12.1 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2111) PDZ_2 PF13180.6 EKX48998.1 - 1.4e-07 31.7 0.1 3.8e-07 30.3 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX48998.1 - 3.9e-05 23.4 0.2 0.00012 21.9 0.2 1.9 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX48998.1 - 0.0011 19.3 0.1 0.0028 18.0 0.1 1.7 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX48998.1 - 0.0012 18.8 0.1 0.0032 17.4 0.1 1.7 1 0 0 1 1 1 1 Tricorn protease PDZ domain DUF3475 PF11961.8 EKX48998.1 - 0.0046 17.0 1.3 0.79 9.8 0.1 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3475) Phage_GP20 PF06810.11 EKX48998.1 - 0.007 16.2 6.5 0.007 16.2 6.5 5.9 2 2 3 5 5 5 1 Phage minor structural protein GP20 KxDL PF10241.9 EKX48998.1 - 1.4 9.2 36.5 2.3 8.6 9.5 5.7 4 2 2 6 6 6 0 Uncharacterized conserved protein FtsX_ECD PF18075.1 EKX48998.1 - 6.2 7.5 25.2 0.68 10.6 4.2 4.6 2 1 2 5 5 5 0 FtsX extracellular domain DUF4209 PF13910.6 EKX48998.1 - 6.4 7.1 7.2 3.3 8.0 0.2 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4209) DUF3037 PF11236.8 EKX48998.1 - 6.6 7.2 10.9 3.9 7.9 0.1 4.2 2 1 2 4 4 4 0 Protein of unknown function (DUF3037) APG5 PF04106.12 EKX48999.1 - 2e-55 187.8 0.0 3.4e-55 187.1 0.0 1.3 2 0 0 2 2 2 1 Autophagy protein Apg5 MMS1_N PF10433.9 EKX49000.1 - 2e-88 297.2 1.4 6e-88 295.6 1.5 1.7 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EKX49000.1 - 6e-69 232.8 0.0 1.8e-68 231.2 0.0 1.9 2 0 0 2 2 2 1 CPSF A subunit region Myb_DNA-bind_7 PF15963.5 EKX49002.1 - 3e-15 55.9 0.3 3e-15 55.9 0.3 1.8 2 0 0 2 2 2 1 Myb DNA-binding like tRNA-synt_1g PF09334.11 EKX49004.1 - 1.2e-76 258.1 0.2 5.4e-74 249.3 0.2 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EKX49004.1 - 1.3e-22 79.8 1.6 1.6e-12 46.5 0.2 3.0 1 1 2 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EKX49004.1 - 9.3e-10 38.3 0.0 6.5e-08 32.3 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EKX49004.1 - 0.022 13.7 0.0 0.049 12.5 0.0 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (K) RCDG1 PF15725.5 EKX49005.1 - 0.21 12.0 0.2 0.21 12.0 0.2 2.6 4 0 0 4 4 4 0 Renal cancer differentiation gene 1 protein EzrA PF06160.12 EKX49008.1 - 0.15 10.2 1.2 0.21 9.7 0.3 1.6 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Peptidase_C1 PF00112.23 EKX49011.1 - 1.2e-63 215.1 2.7 1.5e-63 214.8 2.7 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 EKX49011.1 - 2.2e-05 24.2 1.1 3e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 EKX49011.1 - 0.036 12.9 0.9 4.6 5.9 0.0 2.4 2 0 0 2 2 2 0 Peptidase C1-like family Asp PF00026.23 EKX49012.1 - 1.2e-05 24.9 0.0 0.17 11.2 0.0 3.1 3 0 0 3 3 3 3 Eukaryotic aspartyl protease COMM_domain PF07258.14 EKX49013.1 - 5.9e-18 64.8 0.1 5.9e-18 64.8 0.1 1.8 2 0 0 2 2 2 1 COMM domain Ribosomal_L6 PF00347.23 EKX49014.1 - 7.5e-20 71.4 11.3 3.3e-14 53.3 3.8 2.5 2 1 0 2 2 2 2 Ribosomal protein L6 KH_1 PF00013.29 EKX49014.1 - 0.51 10.2 5.4 0.78 9.6 1.1 2.6 2 2 0 2 2 2 0 KH domain TPP_enzyme_C PF02775.21 EKX49015.1 - 4.1e-09 36.4 0.7 7.1e-09 35.6 0.7 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain POR PF01558.18 EKX49015.1 - 5e-06 26.7 0.0 1.2e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.20 EKX49015.1 - 0.0037 17.1 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain HEAT_2 PF13646.6 EKX49016.1 - 0.00035 20.9 1.4 2.3 8.6 0.0 3.5 3 0 0 3 3 3 2 HEAT repeats Cnd1 PF12717.7 EKX49016.1 - 0.0016 18.5 2.0 0.55 10.3 0.2 3.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Arm_2 PF04826.13 EKX49016.1 - 0.0041 16.6 2.6 0.0047 16.4 0.8 2.0 2 1 0 2 2 2 1 Armadillo-like HEAT_EZ PF13513.6 EKX49016.1 - 0.029 14.9 1.6 2.2 8.9 0.0 3.4 2 1 1 3 3 3 0 HEAT-like repeat Arm PF00514.23 EKX49016.1 - 0.33 11.1 7.1 3.2 7.9 0.7 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 EKX49017.1 - 0.0015 19.1 0.0 7.4 7.3 0.0 3.9 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region DUF3574 PF12098.8 EKX49017.1 - 0.12 12.2 0.0 2.2 8.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) Ipi1_N PF12333.8 EKX49017.1 - 0.46 11.1 6.1 19 5.9 0.1 4.2 3 1 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.22 EKX49017.1 - 2.1 8.8 19.3 8 7.0 0.1 6.7 6 0 0 6 6 6 0 HEAT repeat Zn_clus PF00172.18 EKX49018.1 - 1.5e-07 31.4 11.8 3.8e-07 30.1 11.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIID-31kDa PF02291.15 EKX49019.1 - 1.3e-39 135.0 0.1 1.5e-39 134.8 0.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EKX49019.1 - 4.5e-06 26.6 0.1 7.4e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID_30kDa PF03540.13 EKX49019.1 - 1.3e-05 25.1 0.1 2.8e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit CENP-S PF15630.6 EKX49019.1 - 0.00084 19.7 0.3 0.0012 19.1 0.3 1.3 1 0 0 1 1 1 1 CENP-S protein TFIID_20kDa PF03847.13 EKX49019.1 - 0.02 15.4 0.4 0.033 14.7 0.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A CENP-T_C PF15511.6 EKX49019.1 - 0.032 14.4 0.2 0.043 13.9 0.2 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EKX49019.1 - 0.048 13.8 0.1 0.073 13.3 0.1 1.2 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) SelR PF01641.18 EKX49020.1 - 3.8e-19 68.9 1.9 4.8e-19 68.6 1.9 1.1 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 EKX49020.1 - 0.021 15.0 3.2 0.064 13.5 3.2 1.8 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF1660 PF07874.11 EKX49020.1 - 0.29 11.6 3.1 4.4 7.9 0.7 2.4 2 0 0 2 2 2 0 Prophage protein (DUF1660) GUN4 PF05419.12 EKX49021.1 - 2.7e-38 131.2 0.0 3.4e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 GUN4-like GHMP_kinases_C PF08544.13 EKX49022.1 - 1.6e-17 63.6 0.0 5.8e-17 61.8 0.0 1.9 2 0 0 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 EKX49022.1 - 1.3e-16 59.9 0.1 2.9e-16 58.8 0.1 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 EKX49022.1 - 8.9e-12 45.1 0.0 2.1e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain Pkinase PF00069.25 EKX49023.1 - 3.9e-51 173.9 0.0 1.2e-50 172.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX49023.1 - 2.9e-28 98.9 0.0 5.1e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX49023.1 - 0.021 14.2 0.5 0.064 12.6 0.1 2.0 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EKX49023.1 - 0.046 13.0 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Rhodanese PF00581.20 EKX49024.1 - 2.2e-10 41.0 0.0 3.7e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Kazal_1 PF00050.21 EKX49024.1 - 0.062 13.3 5.1 0.094 12.7 4.3 1.8 1 1 0 1 1 1 0 Kazal-type serine protease inhibitor domain LysM PF01476.20 EKX49025.1 - 5.9e-08 32.6 0.0 2.3e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 LysM domain MMS1_N PF10433.9 EKX49026.1 - 2.2e-150 501.6 0.0 2.9e-150 501.1 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EKX49026.1 - 1.1e-85 287.9 0.0 5.7e-84 282.2 0.0 2.7 3 0 0 3 3 3 1 CPSF A subunit region Ant_C PF05586.11 EKX49026.1 - 0.18 12.4 0.3 0.44 11.2 0.3 1.6 1 0 0 1 1 1 0 Anthrax receptor C-terminus region LSM14 PF12701.7 EKX49027.1 - 1.2e-15 57.4 0.0 1.1e-14 54.3 0.0 2.2 2 0 0 2 2 2 1 Scd6-like Sm domain SM-ATX PF14438.6 EKX49027.1 - 0.025 14.7 0.0 0.096 12.8 0.0 1.9 2 0 0 2 2 2 0 Ataxin 2 SM domain PH PF00169.29 EKX49028.1 - 3.5e-05 24.3 0.0 8.2e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 PH domain EF-hand_7 PF13499.6 EKX49028.1 - 0.00087 19.7 0.0 0.0033 17.9 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX49028.1 - 0.0018 17.7 0.0 0.024 14.2 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EKX49028.1 - 0.0063 16.4 0.0 0.069 13.1 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain Nucleoporin_FG PF13634.6 EKX49029.1 - 0.0013 19.5 76.2 1.4 9.8 0.1 8.1 2 1 3 5 5 5 2 Nucleoporin FG repeat region Chisel PF15355.6 EKX49029.1 - 0.002 18.3 1.6 0.002 18.3 1.6 2.9 2 0 0 2 2 2 1 Stretch-responsive small skeletal muscle X protein, Chisel PDZ_6 PF17820.1 EKX49030.1 - 8.3e-08 32.0 0.0 1.9e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX49030.1 - 4.5e-06 26.9 0.0 8.7e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 PDZ domain TPR_12 PF13424.6 EKX49030.1 - 0.00013 22.1 0.0 0.00036 20.8 0.0 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX49030.1 - 0.00034 20.1 0.2 0.00066 19.1 0.2 1.5 1 0 0 1 1 1 1 MalT-like TPR region ANAPC5 PF12862.7 EKX49030.1 - 0.00096 19.2 0.3 0.013 15.6 0.2 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 5 PDZ PF00595.24 EKX49030.1 - 0.0014 19.0 0.0 0.0036 17.6 0.0 1.7 1 0 0 1 1 1 1 PDZ domain TPR_7 PF13176.6 EKX49030.1 - 0.0018 18.1 0.1 0.44 10.7 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Tricorn_PDZ PF14685.6 EKX49030.1 - 0.0084 16.1 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 Tricorn protease PDZ domain TPR_8 PF13181.6 EKX49030.1 - 0.025 14.8 0.0 0.84 10.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EKX49030.1 - 0.026 14.4 0.0 2.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EKX49030.1 - 0.037 14.1 0.0 15 6.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX49030.1 - 0.05 14.4 0.4 14 6.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX49030.1 - 0.054 13.4 0.1 7.2 6.6 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat EGF_2 PF07974.13 EKX49031.1 - 0.04 14.3 10.9 0.092 13.1 10.9 1.7 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 EKX49031.1 - 8.3 6.6 11.9 1.8 8.7 6.1 2.5 2 0 0 2 2 2 0 Tenascin EGF domain CarboxypepD_reg PF13620.6 EKX49032.1 - 0.023 14.9 0.0 0.96 9.8 0.0 2.8 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain Big_1 PF02369.16 EKX49032.1 - 0.21 11.6 0.0 0.62 10.1 0.0 1.8 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) MMR_HSR1 PF01926.23 EKX49033.1 - 2.4e-14 53.4 0.3 8e-14 51.7 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase NOG1 PF06858.14 EKX49033.1 - 6.3e-11 41.9 0.0 2e-10 40.3 0.0 1.8 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) FeoB_N PF02421.18 EKX49033.1 - 0.0001 21.8 0.0 0.016 14.7 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EKX49033.1 - 0.00024 21.2 2.1 0.023 14.7 0.1 2.7 2 1 1 3 3 3 2 Dynamin family NOG1_N PF17835.1 EKX49033.1 - 0.0023 17.9 3.1 0.0037 17.2 3.1 1.3 1 0 0 1 1 1 1 NOG1 N-terminal helical domain AAA_15 PF13175.6 EKX49033.1 - 0.0091 15.7 1.9 0.033 13.9 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 EKX49033.1 - 0.071 13.6 1.7 0.51 10.8 0.0 2.3 1 1 1 2 2 2 0 AAA domain LCAT PF02450.15 EKX49033.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Methyltransf_28 PF02636.17 EKX49034.1 - 7.1e-25 88.1 0.0 1.5e-24 87.1 0.0 1.5 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase WW PF00397.26 EKX49035.1 - 7.9e-11 41.9 2.5 1.8e-10 40.7 2.5 1.7 1 0 0 1 1 1 1 WW domain Meiosis_expr PF15163.6 EKX49035.1 - 0.061 14.0 0.1 0.19 12.4 0.1 1.8 1 0 0 1 1 1 0 Meiosis-expressed NOA36 PF06524.12 EKX49035.1 - 7.4 5.8 13.1 23 4.2 13.1 1.8 1 0 0 1 1 1 0 NOA36 protein RAP PF08373.10 EKX49036.1 - 0.0061 16.6 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 RAP domain He_PIG PF05345.12 EKX49037.1 - 1.2e-12 47.8 0.0 0.00029 21.0 0.1 4.4 4 0 0 4 4 4 3 Putative Ig domain CHAT PF12770.7 EKX49037.1 - 4.1e-11 42.8 0.0 6.8e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 CHAT domain PDZ_6 PF17820.1 EKX49038.1 - 2.6e-06 27.2 0.0 7.1e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX49038.1 - 0.0002 21.7 0.0 0.0007 19.9 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX49038.1 - 0.0019 18.5 0.0 0.0064 16.8 0.0 1.8 2 0 0 2 2 2 1 PDZ domain T4SS PF07996.11 EKX49038.1 - 0.11 12.9 6.1 3.3 8.1 0.3 2.5 1 1 1 2 2 2 0 Type IV secretion system proteins OMP_b-brl_3 PF14905.6 EKX49038.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Outer membrane protein beta-barrel family HEAT_2 PF13646.6 EKX49038.1 - 0.18 12.2 0.6 1 9.8 0.1 2.3 2 1 0 2 2 2 0 HEAT repeats GvpK PF05121.12 EKX49038.1 - 0.86 9.7 4.2 1.1 9.3 0.5 2.6 2 1 0 2 2 2 0 Gas vesicle protein K Filament PF00038.21 EKX49038.1 - 2.7 7.5 18.7 4.8 6.7 5.7 2.2 1 1 1 2 2 2 0 Intermediate filament protein Ank_4 PF13637.6 EKX49040.1 - 3.5e-07 30.7 0.8 0.00051 20.6 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX49040.1 - 1.1e-06 29.2 0.2 0.00052 20.5 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX49040.1 - 1.9e-06 27.8 0.9 1.6 9.6 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 EKX49040.1 - 8.5e-06 26.0 1.9 0.23 12.0 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EKX49040.1 - 0.013 15.8 0.2 3.1 8.2 0.0 2.7 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Metallophos PF00149.28 EKX49041.1 - 1.9e-33 116.7 0.0 2.3e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EKX49041.1 - 0.088 13.3 0.1 0.19 12.2 0.1 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain PDZ_6 PF17820.1 EKX49042.1 - 9.6e-11 41.4 0.0 2e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX49042.1 - 8.4e-08 32.4 0.0 1.2e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX49042.1 - 1.2e-06 28.8 0.0 1.7e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX49042.1 - 1.6e-05 24.8 0.0 2.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Tricorn protease PDZ domain DUF3336 PF11815.8 EKX49043.1 - 5.2e-36 123.4 0.1 8.9e-36 122.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EKX49043.1 - 6.7e-22 78.7 0.2 2.4e-21 76.9 0.1 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase KTI12 PF08433.10 EKX49044.1 - 1.2e-13 51.2 0.8 1.4e-13 50.9 0.8 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EKX49044.1 - 7.8e-10 39.1 4.7 1.5e-08 34.9 0.8 2.1 2 0 0 2 2 2 2 AAA domain PAS_6 PF08348.11 EKX49045.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 YheO-like PAS domain Amino_oxidase PF01593.24 EKX49047.1 - 9.8e-77 259.1 0.0 1.1e-76 258.9 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EKX49047.1 - 7e-17 61.4 0.1 1.3e-16 60.6 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EKX49047.1 - 7e-10 39.0 0.2 1.3e-08 34.8 0.2 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EKX49047.1 - 3.2e-08 34.0 0.0 0.0041 17.6 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 EKX49047.1 - 9.8e-08 31.2 0.0 0.00033 19.6 0.0 2.1 2 0 0 2 2 2 2 MCRA family Pyr_redox_2 PF07992.14 EKX49047.1 - 3.6e-07 29.7 0.2 0.00014 21.2 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EKX49047.1 - 2.4e-05 23.3 0.2 0.002 16.9 0.4 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 EKX49047.1 - 5.5e-05 22.4 0.3 0.00015 21.0 0.6 1.5 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 EKX49047.1 - 8.7e-05 21.9 0.6 0.00033 20.0 0.4 2.0 3 0 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 EKX49047.1 - 0.00019 20.9 0.0 0.0003 20.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EKX49047.1 - 0.0023 16.9 0.4 1.5 7.6 0.2 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Thi4 PF01946.17 EKX49047.1 - 0.0042 16.4 0.1 0.014 14.6 0.2 1.7 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 EKX49047.1 - 0.02 14.0 0.2 0.085 11.9 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EKX49047.1 - 0.035 13.4 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FMO-like PF00743.19 EKX49047.1 - 0.05 12.0 0.0 0.11 10.9 0.0 1.5 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like GIDA PF01134.22 EKX49047.1 - 0.076 12.1 0.4 0.12 11.4 0.4 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EKX49047.1 - 0.1 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase tRNA-synt_2 PF00152.20 EKX49048.1 - 3.3e-74 249.8 0.0 4.1e-74 249.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 EKX49048.1 - 0.0058 16.2 0.0 0.16 11.4 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) FdhE PF04216.12 EKX49048.1 - 0.1 12.4 0.2 0.19 11.5 0.2 1.4 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation FA_hydroxylase PF04116.13 EKX49049.1 - 6.3e-26 91.3 18.6 1.7e-25 89.9 18.6 1.8 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily 2_5_RNA_ligase2 PF13563.6 EKX49050.1 - 0.043 13.7 0.1 0.099 12.5 0.0 1.6 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily cNMP_binding PF00027.29 EKX49051.1 - 1e-22 80.0 0.0 5.3e-09 36.0 0.0 3.3 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain CdiI_2 PF18593.1 EKX49051.1 - 0.016 15.8 0.4 1.7 9.4 0.1 3.5 3 1 0 3 3 3 0 CdiI immunity protein MORN PF02493.20 EKX49052.1 - 6.1e-21 73.0 15.8 6.6e-08 32.0 0.3 4.1 5 0 0 5 5 5 3 MORN repeat DUF3048_C PF17479.2 EKX49052.1 - 0.16 12.3 1.2 1.2 9.6 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3048) C-terminal domain Beta_helix PF13229.6 EKX49053.1 - 9.6e-06 25.5 8.1 0.0022 17.9 8.2 2.7 1 1 0 1 1 1 1 Right handed beta helix region Chlam_PMP PF02415.17 EKX49053.1 - 0.00017 21.8 14.7 0.038 14.5 1.5 5.4 5 0 0 5 5 5 3 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat NosD PF05048.13 EKX49053.1 - 0.015 14.5 2.0 0.099 11.9 0.3 2.1 2 0 0 2 2 2 0 Periplasmic copper-binding protein (NosD) Pro_isomerase PF00160.21 EKX49054.1 - 1.8e-16 60.8 0.0 3.3e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DnaJ PF00226.31 EKX49056.1 - 0.00063 19.8 0.7 0.0017 18.4 0.3 1.9 2 0 0 2 2 2 1 DnaJ domain zf-dskA_traR PF01258.17 EKX49056.1 - 0.0085 16.0 2.5 0.13 12.2 0.3 2.6 2 0 0 2 2 2 1 Prokaryotic dksA/traR C4-type zinc finger ZZ PF00569.17 EKX49056.1 - 0.036 13.9 2.8 0.065 13.0 2.8 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type DUF4428 PF14471.6 EKX49056.1 - 0.053 13.5 0.4 0.11 12.4 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) DZR PF12773.7 EKX49056.1 - 0.076 13.1 1.1 0.15 12.1 1.1 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-HYPF PF07503.12 EKX49056.1 - 0.26 11.1 2.2 11 6.0 0.0 2.5 2 0 0 2 2 2 0 HypF finger HAD_2 PF13419.6 EKX49057.1 - 1.4e-26 93.7 0.0 1.7e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EKX49057.1 - 1.3e-08 35.4 0.0 4.1e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EKX49057.1 - 1.5e-05 25.0 0.0 2.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like SNF2_N PF00176.23 EKX49058.1 - 2.8e-54 184.2 0.1 3.9e-54 183.7 0.1 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX49058.1 - 1.1e-14 54.7 0.0 4.4e-14 52.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX49058.1 - 3.9e-10 40.0 0.1 1.7e-07 31.4 0.0 2.2 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EKX49058.1 - 0.0056 16.4 0.2 0.38 10.4 0.1 2.5 2 1 0 2 2 2 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 EKX49058.1 - 0.1 12.9 0.0 0.58 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Robl_LC7 PF03259.17 EKX49059.1 - 4.6e-18 64.8 0.0 5.2e-18 64.6 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 EKX49059.1 - 0.053 13.4 0.0 0.084 12.8 0.0 1.3 1 1 0 1 1 1 0 Ragulator complex protein LAMTOR5 Regulator_TrmB PF11495.8 EKX49059.1 - 0.15 11.2 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB U-box PF04564.15 EKX49061.1 - 1.7e-15 56.9 0.0 4.1e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 EKX49061.1 - 0.015 15.4 0.0 0.04 14.1 0.0 1.6 2 0 0 2 2 2 0 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 EKX49061.1 - 0.021 14.7 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit KilA-N PF04383.13 EKX49062.1 - 0.00082 19.2 1.0 0.049 13.5 0.0 2.4 1 1 1 2 2 2 2 KilA-N domain FAST_1 PF06743.15 EKX49063.1 - 3e-11 43.1 0.1 0.0012 18.8 0.0 5.2 4 2 2 6 6 6 5 FAST kinase-like protein, subdomain 1 DUF1601 PF07671.11 EKX49063.1 - 0.13 12.2 0.5 3.7 7.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1601) cobW PF02492.19 EKX49064.1 - 5e-54 182.6 2.9 6.7e-54 182.1 2.9 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EKX49064.1 - 1.1e-21 76.5 0.0 2.2e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain Ank_2 PF12796.7 EKX49064.1 - 6.1e-12 46.0 0.0 1.3e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX49064.1 - 6.5e-11 42.5 0.0 2.1e-06 28.2 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX49064.1 - 1.4e-09 37.9 0.3 0.0039 17.6 0.2 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EKX49064.1 - 4e-09 36.0 0.0 0.00036 20.8 0.0 4.1 3 1 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EKX49064.1 - 6.5e-07 29.5 0.1 0.0028 18.0 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) RsgA_GTPase PF03193.16 EKX49064.1 - 4.1e-05 23.6 0.0 0.15 12.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EKX49064.1 - 0.0044 17.1 0.0 0.014 15.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 EKX49064.1 - 0.0057 15.7 0.0 0.073 12.0 0.0 2.6 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 EKX49064.1 - 0.016 15.1 0.1 0.043 13.7 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 EKX49064.1 - 0.021 15.1 0.0 0.056 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EKX49064.1 - 0.024 13.7 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase_2 PF01637.18 EKX49064.1 - 0.028 14.4 0.1 0.046 13.6 0.1 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 EKX49064.1 - 0.03 13.6 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 EKX49064.1 - 0.039 14.3 0.0 0.098 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 EKX49064.1 - 0.071 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 EKX49064.1 - 0.082 12.6 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EKX49064.1 - 0.1 13.1 0.3 0.89 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EKX49064.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 EKX49064.1 - 0.15 12.6 0.4 0.57 10.7 0.2 2.0 1 1 1 2 2 2 0 ABC transporter Ribosomal_60s PF00428.19 EKX49064.1 - 0.36 11.5 5.4 0.26 11.9 2.8 2.2 2 0 0 2 2 1 0 60s Acidic ribosomal protein PDZ_6 PF17820.1 EKX49065.1 - 8.3e-13 48.0 0.1 1.1e-12 47.5 0.1 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX49065.1 - 3.4e-12 46.5 0.1 3.9e-12 46.3 0.1 1.1 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX49065.1 - 1.2e-06 28.8 0.0 1.3e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX49065.1 - 0.0003 20.7 0.0 0.00039 20.3 0.0 1.2 1 0 0 1 1 1 1 Tricorn protease PDZ domain SET PF00856.28 EKX49066.1 - 4.4e-10 40.2 0.3 2.9e-09 37.5 0.0 2.5 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.18 EKX49066.1 - 2.1e-05 24.5 5.5 2.1e-05 24.5 5.5 2.1 2 0 0 2 2 2 1 MYND finger YabA PF06156.13 EKX49066.1 - 0.91 10.2 7.4 67 4.2 0.0 3.9 3 1 0 3 3 3 0 Initiation control protein YabA SHIPPO-rpt PF07004.12 EKX49067.1 - 6.2e-08 33.2 19.4 0.23 12.4 0.5 6.6 6 0 0 6 6 6 5 Sperm-tail PG-rich repeat DUF4423 PF14394.6 EKX49067.1 - 0.036 13.8 1.2 0.066 12.9 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) RTC PF01137.21 EKX49068.1 - 9.9e-61 204.8 0.4 1.2e-60 204.5 0.4 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 EKX49068.1 - 2.3e-07 31.3 0.3 5.5e-07 30.0 0.3 1.8 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Laminin_II PF06009.12 EKX49070.1 - 0.11 12.5 12.6 1.6 8.7 3.8 2.8 2 0 0 2 2 2 0 Laminin Domain II Ge1_WD40 PF16529.5 EKX49070.1 - 0.15 11.0 4.6 0.46 9.4 0.7 2.5 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4140 PF13600.6 EKX49070.1 - 0.84 10.1 12.4 2.1 8.9 0.2 4.1 4 0 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) DUF572 PF04502.13 EKX49071.1 - 4.3e-57 194.2 2.7 5.1e-57 194.0 2.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf_UBZ PF18439.1 EKX49071.1 - 0.089 12.4 0.1 0.089 12.4 0.1 1.8 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger PDZ PF00595.24 EKX49073.1 - 9.9e-09 35.4 0.1 2.5e-08 34.1 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX49073.1 - 2.5e-08 33.6 0.1 5.9e-08 32.4 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX49073.1 - 0.00068 19.9 0.1 0.0021 18.4 0.1 1.9 1 0 0 1 1 1 1 PDZ domain PX PF00787.24 EKX49074.1 - 4e-21 75.1 2.3 4.4e-21 75.0 0.1 2.1 2 1 0 2 2 2 1 PX domain Vps5 PF09325.10 EKX49074.1 - 1.8e-06 27.7 18.0 8.7e-05 22.2 18.0 2.2 1 1 0 1 1 1 1 Vps5 C terminal like BAR_3_WASP_bdg PF10456.9 EKX49074.1 - 0.00055 19.5 0.4 0.00055 19.5 0.4 1.9 2 2 1 3 3 3 1 WASP-binding domain of Sorting nexin protein Acetyltransf_1 PF00583.25 EKX49074.1 - 0.056 13.7 0.1 0.19 11.9 0.1 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family MS_channel PF00924.18 EKX49075.1 - 1.4e-26 93.3 0.1 1.9e-26 92.9 0.1 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel POR PF01558.18 EKX49076.1 - 8.7e-17 61.7 0.0 1.8e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase TPP_enzyme_C PF02775.21 EKX49076.1 - 1.1e-09 38.2 1.5 2.5e-09 37.1 1.5 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_C PF02780.20 EKX49076.1 - 0.0071 16.2 0.0 0.026 14.4 0.0 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain 2-Hacid_dh_C PF02826.19 EKX49076.1 - 0.15 11.4 0.1 1.2 8.5 0.1 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TIM PF00121.18 EKX49077.1 - 6.7e-84 281.1 0.0 7.6e-84 280.9 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase AP_endonuc_2 PF01261.24 EKX49077.1 - 0.0067 15.9 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Peptidase_C97 PF05903.14 EKX49078.1 - 7.5e-26 90.8 0.1 9.5e-26 90.4 0.1 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain IFT57 PF10498.9 EKX49079.1 - 0.00036 19.6 23.9 0.00036 19.6 23.9 3.4 2 2 1 4 4 4 1 Intra-flagellar transport protein 57 Spc7 PF08317.11 EKX49079.1 - 0.0021 17.0 20.1 0.0021 17.0 20.1 4.5 2 2 2 4 4 4 2 Spc7 kinetochore protein COG2 PF06148.11 EKX49079.1 - 0.0038 17.3 6.6 0.0038 17.3 6.6 5.0 3 1 1 5 5 5 1 COG (conserved oligomeric Golgi) complex component, COG2 BST2 PF16716.5 EKX49079.1 - 0.039 14.5 2.0 0.039 14.5 2.0 6.8 3 2 6 9 9 9 0 Bone marrow stromal antigen 2 PRK PF00485.18 EKX49082.1 - 3.6e-10 39.9 0.1 3.7e-09 36.6 0.1 2.5 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Atx10homo_assoc PF09759.9 EKX49082.1 - 1.6e-08 34.5 0.4 0.36 10.9 0.0 4.6 4 0 0 4 4 4 3 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 EKX49082.1 - 0.00037 20.1 0.1 0.00078 19.0 0.1 1.5 1 0 0 1 1 1 1 Armadillo-like Arm PF00514.23 EKX49082.1 - 0.0004 20.3 5.9 0.64 10.1 0.0 6.1 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat AAA_18 PF13238.6 EKX49082.1 - 0.017 15.7 0.0 0.6 10.7 0.0 3.5 2 1 1 3 3 3 0 AAA domain GGDEF_2 PF17853.1 EKX49082.1 - 0.27 11.5 1.4 0.92 9.8 0.4 2.5 2 0 0 2 2 2 0 GGDEF-like domain Pkinase_Tyr PF07714.17 EKX49083.1 - 8.3e-48 162.9 0.0 1.1e-47 162.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX49083.1 - 1.7e-41 142.3 0.0 2.1e-41 142.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EKX49083.1 - 0.00081 19.4 0.7 0.0068 16.4 0.1 2.3 1 1 2 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EKX49083.1 - 0.013 14.6 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 EKX49083.1 - 0.049 13.2 0.1 0.08 12.5 0.1 1.3 1 0 0 1 1 1 0 RIO1 family EcKinase PF02958.20 EKX49083.1 - 0.21 10.9 0.0 0.66 9.2 0.0 1.7 2 0 0 2 2 2 0 Ecdysteroid kinase Guanylate_cyc PF00211.20 EKX49084.1 - 8.6e-53 178.7 0.0 1e-52 178.5 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain dsDNA_bind PF01984.20 EKX49084.1 - 0.11 12.7 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Double-stranded DNA-binding domain BAF PF02961.14 EKX49085.1 - 2.2e-09 37.6 0.1 2.7e-09 37.3 0.1 1.1 1 0 0 1 1 1 1 Barrier to autointegration factor TerY_C PF15616.6 EKX49085.1 - 0.039 14.1 0.2 0.057 13.5 0.1 1.4 1 1 0 1 1 1 0 TerY-C metal binding domain FANCI_S3 PF14677.6 EKX49085.1 - 0.083 12.6 0.1 0.092 12.4 0.1 1.1 1 0 0 1 1 1 0 FANCI solenoid 3 Exo_endo_phos PF03372.23 EKX49086.1 - 8.1e-11 41.9 0.0 3.6e-10 39.8 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PolyA_pol_RNAbd PF12627.7 EKX49088.1 - 2.1e-10 40.2 0.0 4.9e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A FliG_C PF01706.16 EKX49088.1 - 0.046 13.9 0.1 0.19 11.9 0.0 2.0 2 0 0 2 2 2 0 FliG C-terminal domain QSregVF PF13652.6 EKX49088.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor Clathrin PF00637.20 EKX49088.1 - 0.16 11.8 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Region in Clathrin and VPS DUF5398 PF17376.2 EKX49088.1 - 0.23 12.1 0.9 0.83 10.3 0.0 2.2 3 0 0 3 3 3 0 Family of unknown function (DUF5398) PEPcase PF00311.17 EKX49089.1 - 3.8e-247 822.4 0.0 6.2e-247 821.6 0.0 1.3 1 1 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 EKX49089.1 - 4e-05 22.3 0.0 7.5e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase Acid_phosphat_B PF03767.14 EKX49090.1 - 0.075 12.6 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) CYTH PF01928.21 EKX49091.1 - 4.2e-06 26.8 0.3 6e-06 26.3 0.3 1.3 1 0 0 1 1 1 1 CYTH domain SDA1 PF05285.12 EKX49091.1 - 2.5 7.4 56.6 3.4 7.0 56.6 1.3 1 0 0 1 1 1 0 SDA1 GBP_C PF02841.14 EKX49092.1 - 3.5 6.9 17.1 0.21 10.9 12.3 1.4 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain O-antigen_lig PF13425.6 EKX49092.1 - 5.4 5.7 3.9 5.4 5.7 3.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Presenilin PF01080.17 EKX49092.1 - 7.6 5.2 5.4 8.6 5.0 5.4 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_C12 PF01088.21 EKX49093.1 - 2.7e-66 223.3 0.1 7.3e-66 221.9 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EKX49093.1 - 3.8e-19 68.3 2.4 9e-19 67.1 2.4 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Atg14 PF10186.9 EKX49093.1 - 0.025 13.7 1.5 0.036 13.1 1.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 KIP1 PF07765.12 EKX49093.1 - 0.042 14.0 0.4 0.12 12.5 0.2 2.0 1 1 0 1 1 1 0 KIP1-like protein Amidase_5 PF05382.13 EKX49094.1 - 0.15 12.0 0.1 1.2 9.0 0.0 2.0 2 0 0 2 2 2 0 Bacteriophage peptidoglycan hydrolase CzcE PF16986.5 EKX49095.1 - 0.014 15.7 0.0 70 3.8 0.0 3.3 3 0 0 3 3 3 0 Heavy-metal resistance protein CzcE DUF3005 PF11448.8 EKX49095.1 - 0.06 13.4 1.7 10 6.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3005) BAH PF01426.18 EKX49095.1 - 0.12 12.2 0.0 24 4.8 0.0 2.5 2 0 0 2 2 2 0 BAH domain Mad3_BUB1_I PF08311.12 EKX49095.1 - 0.15 12.1 1.5 43 4.1 0.0 3.2 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 WW PF00397.26 EKX49098.1 - 1.1e-06 28.6 5.8 2.1e-06 27.7 5.8 1.5 1 1 0 1 1 1 1 WW domain MMADHC PF10229.9 EKX49098.1 - 0.033 13.9 0.2 0.066 12.9 0.2 1.4 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type D protein IncD PF17628.2 EKX49098.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Inclusion membrane protein D DUF2300 PF10062.9 EKX49099.1 - 0.079 13.0 0.2 0.13 12.3 0.2 1.2 1 0 0 1 1 1 0 Predicted secreted protein (DUF2300) PA14 PF07691.12 EKX49100.1 - 7.9e-08 32.2 0.1 1.4e-07 31.4 0.1 1.4 1 0 0 1 1 1 1 PA14 domain Arginosuc_synth PF00764.19 EKX49101.1 - 5.1e-147 490.2 0.0 5.8e-147 490.0 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 EKX49101.1 - 0.0018 17.8 0.0 0.0029 17.1 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EKX49101.1 - 0.1 11.4 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase Glyco_hydr_30_2 PF14587.6 EKX49101.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 NAD_binding_2 PF03446.15 EKX49103.1 - 2.5e-39 135.0 0.0 4e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EKX49103.1 - 5.6e-25 88.0 1.9 6.3e-25 87.8 0.7 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PDH PF02153.17 EKX49103.1 - 0.0031 16.5 0.0 0.0042 16.1 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase Shikimate_DH PF01488.20 EKX49103.1 - 0.0034 17.4 0.1 0.019 15.0 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 EKX49103.1 - 0.14 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ank_2 PF12796.7 EKX49104.1 - 3.5e-55 184.6 18.3 2.3e-14 53.7 0.6 5.9 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX49104.1 - 5.8e-45 151.1 16.2 4.5e-12 46.2 0.2 9.4 3 3 9 12 12 12 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX49104.1 - 3.7e-36 119.0 8.9 0.00031 20.9 0.0 12.9 13 0 0 13 13 13 9 Ankyrin repeat Ank_5 PF13857.6 EKX49104.1 - 1.6e-31 107.9 18.6 1.5e-05 25.2 0.2 11.5 1 1 11 12 12 12 6 Ankyrin repeats (many copies) Ank PF00023.30 EKX49104.1 - 9.5e-31 104.9 16.1 0.0057 17.0 0.0 12.7 13 0 0 13 13 13 8 Ankyrin repeat NIP_1 PF08995.10 EKX49104.1 - 6.5 7.2 6.5 54 4.3 0.1 4.3 4 1 0 5 5 5 0 Necrosis inducing protein-1 RWP-RK PF02042.15 EKX49105.1 - 2.1e-12 46.8 0.1 3.3e-12 46.2 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX49105.1 - 0.009 15.8 0.1 1.1 9.1 0.0 2.3 1 1 1 2 2 2 2 Bacterial regulatory protein, Fis family RWP-RK PF02042.15 EKX49106.1 - 5.5e-16 58.3 0.0 8.6e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX49106.1 - 0.011 15.6 0.0 1 9.2 0.0 2.3 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family FAD_binding_3 PF01494.19 EKX49108.1 - 5.2e-15 55.5 0.2 3.9e-07 29.6 0.1 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EKX49108.1 - 0.00023 21.3 0.0 0.00074 19.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EKX49108.1 - 0.0005 19.7 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EKX49108.1 - 0.0012 18.1 0.3 0.011 15.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EKX49108.1 - 0.0052 15.5 0.0 0.1 11.3 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 EKX49108.1 - 0.014 14.7 0.1 0.03 13.6 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 EKX49108.1 - 0.025 14.0 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 ThiF family FAD_binding_2 PF00890.24 EKX49108.1 - 0.032 13.3 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 EKX49108.1 - 0.041 13.9 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Glu_dehyd_C PF16912.5 EKX49108.1 - 0.045 13.2 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Lycopene_cycl PF05834.12 EKX49108.1 - 0.054 12.5 0.1 0.19 10.7 0.1 1.8 1 1 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 EKX49108.1 - 0.072 12.3 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 EKX49108.1 - 0.09 12.1 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AAA PF00004.29 EKX49109.1 - 1.9e-32 112.4 0.0 7.4e-32 110.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EKX49109.1 - 5.4e-08 32.5 0.0 1.2e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EKX49109.1 - 3.2e-05 23.7 0.1 0.00015 21.6 0.0 2.1 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain Vps4_C PF09336.10 EKX49109.1 - 0.00045 20.2 0.1 0.0015 18.5 0.0 1.9 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain TIP49 PF06068.13 EKX49109.1 - 0.00074 18.8 0.0 0.0014 17.9 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 EKX49109.1 - 0.0016 18.6 0.0 0.0062 16.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EKX49109.1 - 0.006 16.9 0.2 0.11 12.8 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EKX49109.1 - 0.0086 16.1 0.1 0.057 13.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EKX49109.1 - 0.01 15.6 0.0 0.031 14.0 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EKX49109.1 - 0.022 14.2 0.0 0.068 12.5 0.0 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TniB PF05621.11 EKX49109.1 - 0.024 14.1 0.3 8.1 5.8 0.0 2.6 2 1 1 3 3 3 0 Bacterial TniB protein AAA_16 PF13191.6 EKX49109.1 - 0.025 15.0 2.9 0.071 13.5 0.6 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 EKX49109.1 - 0.054 13.6 0.0 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EKX49109.1 - 0.075 13.6 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EKX49109.1 - 0.1 13.0 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 EKX49109.1 - 0.1 12.6 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Voltage_CLC PF00654.20 EKX49110.1 - 1.4e-52 179.2 12.1 1.4e-52 179.2 12.1 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel Ino80_Iec3 PF14612.6 EKX49110.1 - 0.0088 16.7 0.0 0.012 16.2 0.0 1.1 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling TraL PF07178.11 EKX49110.1 - 0.088 13.3 4.3 9.3 6.8 0.3 3.4 3 0 0 3 3 3 0 TraL protein Trypsin_2 PF13365.6 EKX49111.1 - 6.6e-35 121.2 1.0 2.2e-34 119.5 0.4 2.0 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 EKX49111.1 - 1.6e-16 60.8 0.0 2.4e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 EKX49111.1 - 5.3e-13 49.1 0.1 1.3e-12 47.9 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX49111.1 - 1.5e-07 31.2 2.0 0.00036 20.3 0.1 2.6 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 EKX49111.1 - 0.013 15.8 0.2 0.18 12.2 0.2 2.5 1 1 0 1 1 1 0 PDZ domain Peptidase_S32 PF05579.13 EKX49111.1 - 0.023 13.9 1.5 0.69 9.1 0.1 2.5 2 1 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Peptidase_S29 PF02907.15 EKX49111.1 - 0.031 14.0 0.2 0.083 12.6 0.0 1.8 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease GRASP55_65 PF04495.14 EKX49111.1 - 0.041 14.2 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Peptidase_S46 PF10459.9 EKX49111.1 - 0.26 9.9 1.5 0.3 9.7 0.5 1.4 2 0 0 2 2 2 0 Peptidase S46 PRKG1_interact PF15898.5 EKX49113.1 - 2.9 8.8 9.4 5.4 8.0 1.8 2.9 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain IBN_N PF03810.19 EKX49114.1 - 3.9e-12 45.9 0.0 1e-09 38.2 0.0 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 EKX49114.1 - 6.8e-09 35.0 0.0 7.3e-08 31.6 0.0 2.5 3 0 0 3 3 3 1 Cse1 HEAT_EZ PF13513.6 EKX49114.1 - 0.00043 20.7 1.9 0.74 10.4 0.0 4.5 3 1 1 4 4 4 1 HEAT-like repeat Xpo1 PF08389.12 EKX49114.1 - 0.0045 17.1 0.0 0.032 14.3 0.0 2.5 2 0 0 2 2 2 1 Exportin 1-like protein HEAT PF02985.22 EKX49114.1 - 0.0054 16.9 0.5 4 7.9 0.0 5.1 5 0 0 5 5 5 1 HEAT repeat NUC130_3NT PF08158.12 EKX49114.1 - 0.06 13.7 0.6 3.3 8.1 0.1 3.3 3 0 0 3 3 3 0 NUC130/3NT domain Ion_trans PF00520.31 EKX49115.1 - 8.4e-33 113.6 17.3 1.3e-32 113.0 17.3 1.1 1 0 0 1 1 1 1 Ion transport protein EF-hand_1 PF00036.32 EKX49115.1 - 9.1e-15 53.0 2.2 5.4e-05 22.5 0.3 4.2 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EKX49115.1 - 1.4e-13 49.6 0.2 0.00097 18.9 0.1 4.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 EKX49115.1 - 2e-12 46.0 3.7 2.3e-06 26.9 0.1 4.0 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EKX49115.1 - 5.1e-11 42.9 0.9 1.4e-06 28.6 0.2 3.0 2 0 0 2 2 2 2 EF-hand domain pair PKD_channel PF08016.12 EKX49115.1 - 1.2e-06 27.5 8.8 1.5e-05 23.9 3.0 2.2 2 0 0 2 2 2 2 Polycystin cation channel EF-hand_8 PF13833.6 EKX49115.1 - 3.3e-06 26.8 6.8 0.0073 16.1 2.5 4.2 3 1 1 4 4 4 2 EF-hand domain pair PH PF00169.29 EKX49115.1 - 1.2e-05 25.7 0.0 2.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 PH domain CheF-arch PF04283.12 EKX49115.1 - 0.002 17.9 0.2 0.041 13.6 0.1 2.3 2 0 0 2 2 2 1 Chemotaxis signal transduction system protein F from archaea FliS PF02561.14 EKX49115.1 - 0.011 16.0 0.2 0.07 13.4 0.0 2.4 2 0 0 2 2 2 0 Flagellar protein FliS Dockerin_1 PF00404.18 EKX49115.1 - 0.016 15.4 0.4 0.045 13.9 0.4 1.9 1 1 0 1 1 1 0 Dockerin type I domain EF-hand_4 PF12763.7 EKX49115.1 - 0.025 14.5 0.5 12 5.9 0.0 3.4 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand DUF2608 PF11019.8 EKX49115.1 - 0.061 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) DUF2427 PF10348.9 EKX49115.1 - 0.083 12.7 0.3 7 6.5 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) RWP-RK PF02042.15 EKX49117.1 - 1.1e-14 54.1 0.2 1.7e-14 53.5 0.2 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_24 PF13412.6 EKX49117.1 - 0.16 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding EspB_PE PF18625.1 EKX49118.1 - 0.0096 16.4 0.3 0.036 14.5 0.1 2.1 2 0 0 2 2 2 1 ESX-1 secreted protein B PE domain DUF4149 PF13664.6 EKX49120.1 - 0.14 12.5 4.9 0.53 10.6 2.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) MORN PF02493.20 EKX49121.1 - 5.8e-31 104.5 38.3 1.8e-08 33.7 0.6 9.2 9 1 0 9 9 9 8 MORN repeat Red1 PF07964.11 EKX49121.1 - 5.1 5.2 7.4 6.9 4.8 7.4 1.0 1 0 0 1 1 1 0 Rec10 / Red1 TCR PF03638.15 EKX49122.1 - 6.7e-11 42.3 24.1 6.7e-11 42.3 24.1 3.4 3 1 1 4 4 4 1 Tesmin/TSO1-like CXC domain, cysteine-rich domain PHD PF00628.29 EKX49122.1 - 1.9e-09 37.3 9.2 1.9e-09 37.3 9.2 3.2 2 2 1 3 3 3 1 PHD-finger PsbX PF06596.11 EKX49124.1 - 0.084 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) WD40 PF00400.32 EKX49125.1 - 0.0061 17.4 1.7 3.5 8.7 0.3 2.8 2 1 0 2 2 2 2 WD domain, G-beta repeat WD40 PF00400.32 EKX49126.1 - 8.1e-07 29.7 0.0 0.0053 17.6 0.0 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF2181 PF10223.9 EKX49127.1 - 3.3e-21 75.9 0.0 4.2e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2181) PDZ PF00595.24 EKX49129.1 - 6.2e-13 48.9 0.2 3.5e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EKX49129.1 - 4.3e-12 45.7 0.5 3.7e-07 29.9 0.1 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX49129.1 - 4.8e-10 39.6 0.0 4.3e-05 23.8 0.0 2.6 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 EKX49129.1 - 5.6e-06 26.2 0.2 0.0034 17.3 0.0 2.8 2 1 0 2 2 2 2 Tricorn protease PDZ domain SnoaL_3 PF13474.6 EKX49129.1 - 0.025 14.9 0.0 0.061 13.6 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like domain DUF1690 PF07956.11 EKX49129.1 - 5.8 7.3 7.8 1.8 9.0 0.0 3.0 3 0 0 3 3 3 0 Protein of Unknown function (DUF1690) LRR_9 PF14580.6 EKX49130.1 - 2.2e-09 37.1 3.6 6.3e-08 32.3 3.5 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 EKX49130.1 - 3.4e-09 36.8 19.6 4.1e-06 27.1 1.1 3.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX49130.1 - 3e-07 30.1 15.4 0.00033 20.4 1.3 3.8 2 1 2 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 EKX49130.1 - 0.84 9.8 8.3 7.9 6.8 0.2 4.0 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 EKX49130.1 - 4.7 8.2 13.7 70 4.6 0.3 5.3 4 1 1 5 5 5 0 Leucine Rich Repeat YtxH PF12732.7 EKX49130.1 - 4.9 7.8 11.6 1.2 9.7 1.6 4.4 3 0 0 3 3 3 0 YtxH-like protein RTBV_P46 PF06216.11 EKX49130.1 - 7.1 5.4 7.2 0.19 10.6 0.6 1.7 2 0 0 2 2 2 0 Rice tungro bacilliform virus P46 protein DHHC PF01529.20 EKX49131.1 - 4e-30 104.7 15.7 4e-30 104.7 15.7 2.2 2 1 0 2 2 2 1 DHHC palmitoyltransferase Halogen_Hydrol PF10112.9 EKX49131.1 - 6.9e-05 23.0 0.2 0.0038 17.3 0.0 2.3 2 0 0 2 2 2 1 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF2207 PF09972.9 EKX49131.1 - 0.17 10.6 1.8 3.8 6.2 0.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF2304 PF10066.9 EKX49131.1 - 0.26 11.5 0.1 0.26 11.5 0.1 3.9 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2304) DUF4692 PF15763.5 EKX49131.1 - 0.4 11.1 0.0 0.4 11.1 0.0 2.1 3 0 0 3 3 3 0 Regulator of human erythroid cell expansion (RHEX) Tmemb_9 PF05434.11 EKX49131.1 - 0.66 9.9 8.5 4.3 7.2 0.1 2.9 2 1 1 3 3 3 0 TMEM9 DUF4231 PF14015.6 EKX49131.1 - 0.81 10.2 5.6 1.3 9.5 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Lipase_3 PF01764.25 EKX49132.1 - 1.5e-12 47.5 0.0 2.6e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.20 EKX49132.1 - 6.3e-06 26.5 0.0 1.3e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_8 PF06259.12 EKX49132.1 - 0.00036 20.2 0.0 0.007 16.0 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase PGAP1 PF07819.13 EKX49132.1 - 0.0024 17.6 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 EKX49132.1 - 0.0033 17.0 0.0 0.0061 16.1 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.7 EKX49132.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family PDZ_2 PF13180.6 EKX49133.1 - 0.0089 16.3 0.0 0.067 13.5 0.0 2.3 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX49133.1 - 0.012 15.9 0.0 0.055 13.8 0.0 2.2 2 0 0 2 2 2 0 PDZ domain DUF4279 PF14106.6 EKX49133.1 - 0.49 10.6 3.7 0.54 10.5 0.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4279) Polbeta PF18765.1 EKX49134.1 - 0.00059 19.9 0.0 0.0017 18.4 0.0 1.9 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase NTP_transf_2 PF01909.23 EKX49134.1 - 0.01 16.1 0.0 0.047 14.0 0.0 2.1 2 0 0 2 2 2 0 Nucleotidyltransferase domain Elf-1_N PF12310.8 EKX49134.1 - 0.15 12.6 0.0 9.2 6.9 0.0 2.4 2 0 0 2 2 2 0 Transcription factor protein N terminal JmjC PF02373.22 EKX49136.1 - 1.6e-39 134.9 1.0 2.6e-39 134.2 1.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 EKX49136.1 - 2.2e-15 56.3 1.1 5.1e-15 55.2 0.5 2.0 2 0 0 2 2 2 1 jmjN domain SHMT PF00464.19 EKX49136.1 - 0.12 11.0 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Serine hydroxymethyltransferase Kinesin PF00225.23 EKX49137.1 - 8.6e-24 84.1 0.0 9.3e-24 84.0 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX49137.1 - 2.9e-17 63.0 0.0 3.3e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 Microtubule binding DUF2183 PF09949.9 EKX49138.1 - 0.015 15.6 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) Strumpellin PF10266.9 EKX49139.1 - 0 1413.7 10.0 0 1413.5 10.0 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin TPH PF13868.6 EKX49140.1 - 0.73 8.3 15.0 1.6 7.2 3.9 2.1 2 0 0 2 2 2 0 Trichohyalin-plectin-homology domain FlaC_arch PF05377.11 EKX49142.1 - 0.86 10.0 7.6 0.15 12.5 0.8 2.9 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) Peptidase_C78 PF07910.13 EKX49143.1 - 4.5e-05 23.0 0.0 5.5e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 Ion_trans PF00520.31 EKX49144.1 - 1.1e-12 47.8 12.5 1.6e-12 47.2 12.5 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX49144.1 - 2e-10 40.5 5.2 2e-10 40.5 5.2 2.4 3 0 0 3 3 3 1 Ion channel cNMP_binding PF00027.29 EKX49144.1 - 2.8e-08 33.7 0.0 7.7e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Dynein_light PF01221.18 EKX49146.1 - 2.2e-24 85.6 0.5 2.6e-24 85.4 0.5 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Nop PF01798.18 EKX49146.1 - 0.026 14.0 0.0 0.031 13.7 0.0 1.0 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin DUF1428 PF07237.11 EKX49146.1 - 0.051 13.9 0.2 0.066 13.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) TFIIE_alpha PF02002.17 EKX49147.1 - 0.11 12.3 1.1 0.52 10.2 0.4 2.0 2 0 0 2 2 2 0 TFIIE alpha subunit Glyco_transf_8 PF01501.20 EKX49148.1 - 0.064 12.8 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 8 tRNA-synt_1g PF09334.11 EKX49149.1 - 6.5e-95 318.2 2.4 1e-54 185.8 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EKX49149.1 - 3.1e-39 134.7 2.3 1.7e-21 76.1 0.1 4.0 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA_bind PF01588.20 EKX49149.1 - 1.1e-20 73.5 0.3 2.1e-20 72.6 0.3 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1e PF01406.19 EKX49149.1 - 8e-13 48.4 0.1 1.8e-05 24.3 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EKX49149.1 - 3.2e-07 29.6 0.0 0.0003 19.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (K) SDA1 PF05285.12 EKX49150.1 - 1.1 8.6 76.4 1.4 8.2 76.4 1.1 1 0 0 1 1 1 0 SDA1 WD40 PF00400.32 EKX49151.1 - 1.2e-92 301.2 44.8 2.1e-10 41.0 0.1 12.2 11 1 1 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX49151.1 - 4.1e-38 129.6 12.5 0.0003 21.0 0.0 10.2 1 1 9 10 10 10 10 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EKX49151.1 - 1.1e-14 54.8 0.1 6.7e-06 26.1 0.0 5.3 2 1 4 6 6 6 5 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EKX49151.1 - 2.2e-12 46.6 4.0 0.071 12.1 0.0 8.3 1 1 4 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EKX49151.1 - 1.4e-11 44.0 1.1 0.81 9.7 0.0 6.7 7 0 0 7 7 7 4 WD40-like Beta Propeller Repeat Gmad1 PF10647.9 EKX49151.1 - 2.3e-06 27.6 8.4 0.21 11.3 4.7 5.4 3 1 2 5 5 5 3 Lipoprotein LpqB beta-propeller domain WD40_like PF17005.5 EKX49151.1 - 1.4e-05 24.6 0.0 0.29 10.4 0.0 4.2 4 1 0 4 4 4 2 WD40-like domain IKI3 PF04762.12 EKX49151.1 - 0.00016 19.9 4.4 0.052 11.5 0.0 4.1 2 2 2 4 4 4 2 IKI3 family Nucleoporin_N PF08801.11 EKX49151.1 - 0.0077 15.0 7.6 0.45 9.2 0.4 5.0 1 1 4 5 5 5 1 Nup133 N terminal like DPPIV_N PF00930.21 EKX49151.1 - 0.023 13.5 11.2 3.4 6.3 0.3 5.4 4 3 1 5 5 5 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nup160 PF11715.8 EKX49151.1 - 0.034 12.8 12.7 0.16 10.6 0.2 5.5 3 2 2 7 7 7 0 Nucleoporin Nup120/160 Proteasome_A_N PF10584.9 EKX49151.1 - 0.065 12.9 1.7 30 4.4 0.0 4.9 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Patatin PF01734.22 EKX49152.1 - 2.9e-09 37.4 0.2 5.4e-09 36.5 0.2 1.5 1 1 0 1 1 1 1 Patatin-like phospholipase DUF2316 PF10078.9 EKX49154.1 - 0.09 13.0 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) Lipase_3 PF01764.25 EKX49155.1 - 1.6e-13 50.7 0.0 3.1e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EKX49155.1 - 0.09 13.4 0.0 0.13 12.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 EKX49155.1 - 0.097 12.2 0.0 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) ART PF01129.18 EKX49156.1 - 4.2e-05 22.9 0.0 6.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase ADPrib_exo_Tox PF03496.14 EKX49156.1 - 0.0017 17.8 0.0 0.0026 17.1 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosyltransferase exoenzyme Ank_4 PF13637.6 EKX49157.1 - 5.1e-26 90.7 1.0 8.3e-10 39.0 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX49157.1 - 2.3e-23 82.6 4.1 1.5e-12 47.9 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX49157.1 - 8.1e-13 47.3 1.7 0.021 15.3 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EKX49157.1 - 2e-12 47.1 2.3 0.00017 21.8 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EKX49157.1 - 3.9e-12 46.0 4.4 0.0014 19.0 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Laminin_G_3 PF13385.6 EKX49158.1 - 1.4e-12 48.0 5.1 3.4e-12 46.8 5.1 1.7 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Abhydrolase_2 PF02230.16 EKX49161.1 - 3e-17 63.2 0.0 5.1e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase TPR_1 PF00515.28 EKX49161.1 - 2.7e-14 52.3 0.1 0.0018 18.0 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX49161.1 - 4.3e-13 48.3 1.2 0.011 15.8 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 EKX49161.1 - 8.5e-10 39.0 2.4 8.5e-05 23.0 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX49161.1 - 4.1e-08 32.8 0.2 0.018 15.2 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX49161.1 - 3e-06 27.4 4.0 0.0052 17.0 0.5 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX49161.1 - 0.00014 22.3 5.6 0.063 14.1 0.9 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX49161.1 - 0.00016 22.3 3.5 0.051 14.2 1.1 2.4 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX49161.1 - 0.00018 21.3 1.7 6 7.1 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3808 PF10300.9 EKX49161.1 - 0.00078 18.3 0.1 0.001 17.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) ANAPC3 PF12895.7 EKX49161.1 - 0.0049 17.1 0.6 0.013 15.7 0.2 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 EKX49161.1 - 0.01 15.9 1.2 5.4 7.2 0.0 3.0 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 EKX49161.1 - 0.011 16.1 0.5 0.22 12.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EKX49161.1 - 0.024 15.2 6.8 23 6.0 0.9 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EKX49161.1 - 0.056 13.6 4.1 0.42 10.8 0.6 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat Hydrolase_4 PF12146.8 EKX49161.1 - 0.099 11.9 0.0 1.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 TPR_6 PF13174.6 EKX49161.1 - 0.22 12.2 2.8 2.4 9.0 0.5 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat tRNA-synt_2d PF01409.20 EKX49162.1 - 2.3e-38 132.1 0.5 1.7e-37 129.2 0.5 2.3 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 EKX49162.1 - 1.6e-15 57.3 0.0 3.2e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain MORN_2 PF07661.13 EKX49163.1 - 0.059 13.6 0.1 11 6.6 0.0 2.7 2 0 0 2 2 2 0 MORN repeat variant Shisa PF13908.6 EKX49164.1 - 0.025 14.8 0.1 0.027 14.7 0.1 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Orf78 PF06024.12 EKX49164.1 - 0.075 13.3 0.0 0.097 13.0 0.0 1.2 1 0 0 1 1 1 0 Orf78 (ac78) TPR_17 PF13431.6 EKX49165.1 - 1.2e-27 94.2 10.3 0.00017 21.7 0.0 8.0 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 EKX49165.1 - 6.2e-19 66.6 10.1 0.0024 17.9 0.1 7.6 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 EKX49165.1 - 1.8e-18 65.5 12.0 0.0026 17.5 0.3 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 EKX49165.1 - 5.7e-18 63.5 10.6 0.095 12.9 0.0 8.3 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 EKX49165.1 - 7.5e-18 63.7 8.2 0.0077 17.0 0.0 8.5 3 2 6 9 9 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 EKX49165.1 - 4.9e-15 54.9 1.3 0.0057 16.3 0.1 5.8 6 1 0 6 6 6 3 TPR repeat TPR_12 PF13424.6 EKX49165.1 - 1.5e-14 54.1 16.0 0.00076 19.7 1.7 6.1 1 1 6 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.6 EKX49165.1 - 1.9e-12 47.5 3.7 0.11 13.0 0.4 5.9 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 EKX49165.1 - 9.5e-10 39.0 3.9 0.00044 20.8 0.1 5.0 5 1 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX49165.1 - 1.8e-07 30.7 7.9 0.41 10.8 0.0 6.9 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX49165.1 - 2.4e-06 27.6 1.3 0.012 15.7 0.5 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat 14-3-3 PF00244.20 EKX49165.1 - 2.9e-05 23.7 2.2 0.0036 16.8 0.1 3.3 1 1 1 3 3 3 1 14-3-3 protein TPR_6 PF13174.6 EKX49165.1 - 0.00077 19.9 3.9 60 4.6 0.0 6.2 6 1 1 7 7 5 0 Tetratricopeptide repeat Coatomer_E PF04733.14 EKX49165.1 - 0.0013 18.2 4.8 0.42 10.0 0.2 3.6 2 1 1 3 3 3 2 Coatomer epsilon subunit TPR_15 PF13429.6 EKX49165.1 - 0.0022 17.3 0.7 1.3 8.2 0.3 3.1 1 1 1 3 3 3 2 Tetratricopeptide repeat DUF4919 PF16266.5 EKX49165.1 - 0.0055 16.7 2.2 0.28 11.1 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4919) DUF627 PF04781.12 EKX49165.1 - 0.054 13.5 0.5 0.17 11.9 0.2 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF627) TOM20_plant PF06552.12 EKX49165.1 - 0.067 12.9 3.5 2.5 7.8 0.2 3.6 2 2 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 DUF4810 PF16068.5 EKX49165.1 - 0.15 12.6 0.1 0.15 12.6 0.1 2.5 3 1 0 3 3 2 0 Domain of unknown function (DUF4810) TPR_10 PF13374.6 EKX49165.1 - 0.18 11.7 17.3 11 6.1 0.2 6.8 8 0 0 8 8 7 0 Tetratricopeptide repeat Ric8 PF10165.9 EKX49166.1 - 0.011 14.8 1.3 0.4 9.6 1.3 2.1 1 1 0 1 1 1 0 Guanine nucleotide exchange factor synembryn Arch_flagellin PF01917.16 EKX49166.1 - 0.081 13.1 0.6 0.17 12.1 0.6 1.5 1 0 0 1 1 1 0 Archaebacterial flagellin DUF3357 PF11837.8 EKX49166.1 - 0.38 11.2 3.3 0.79 10.2 3.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) U1snRNP70_N PF12220.8 EKX49166.1 - 2.4 8.9 4.6 3.6 8.3 2.6 2.0 1 1 1 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal BCD PF15461.6 EKX49168.1 - 4.5e-57 193.6 16.2 9.1e-57 192.6 16.2 1.4 1 1 0 1 1 1 1 Beta-carotene 15,15'-dioxygenase Gp_dh_C PF02800.20 EKX49170.1 - 3e-58 195.9 0.0 5.6e-58 195.0 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EKX49170.1 - 2.1e-32 111.5 1.0 1.4e-31 108.8 0.1 2.6 3 1 0 3 3 3 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain MFS_1 PF07690.16 EKX49171.1 - 0.00024 20.2 15.4 0.0033 16.4 2.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily CrgA PF06781.12 EKX49171.1 - 2.2 8.4 6.0 10 6.3 3.3 2.9 2 0 0 2 2 2 0 Cell division protein CrgA EF-hand_4 PF12763.7 EKX49172.1 - 0.1 12.6 0.5 0.25 11.3 0.5 1.6 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand LysM PF01476.20 EKX49173.1 - 2.8e-06 27.3 0.1 0.00083 19.4 0.2 3.1 2 0 0 2 2 2 2 LysM domain Bac_rhamnosid_C PF17390.2 EKX49173.1 - 0.12 12.2 0.0 3.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase C-terminal domain PDZ_6 PF17820.1 EKX49174.1 - 1.2e-09 37.8 0.1 2.3e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX49174.1 - 2.3e-07 31.1 0.2 5.3e-07 29.9 0.2 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX49174.1 - 3.1e-07 30.6 0.2 5.9e-07 29.7 0.2 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX49174.1 - 1.6e-05 24.8 0.1 3.7e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 Tricorn protease PDZ domain PDZ_4 PF17816.1 EKX49174.1 - 0.053 13.9 0.7 0.12 12.7 0.2 1.9 1 1 1 2 2 2 0 PDZ domain RNAse_A_bac PF18431.1 EKX49175.1 - 0.075 14.0 0.9 0.38 11.7 0.1 2.5 2 1 0 2 2 2 0 Bacterial CdiA-CT RNAse A domain DUF2808 PF10989.8 EKX49175.1 - 0.2 11.6 0.2 0.49 10.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) COG5 PF10392.9 EKX49175.1 - 0.32 11.2 6.1 0.3 11.3 1.1 2.9 2 0 0 2 2 2 0 Golgi transport complex subunit 5 V_ATPase_I PF01496.19 EKX49175.1 - 0.36 8.7 5.0 0.37 8.7 1.0 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family SOAR PF16533.5 EKX49175.1 - 1.1 9.3 6.5 0.14 12.1 0.2 2.9 3 1 0 3 3 3 0 STIM1 Orai1-activating region Atg14 PF10186.9 EKX49175.1 - 2.9 6.9 22.9 0.71 8.9 7.5 3.0 3 0 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 YabA PF06156.13 EKX49175.1 - 6.5 7.4 29.2 0.99 10.1 7.2 5.6 3 2 3 6 6 6 0 Initiation control protein YabA DnaB_2 PF07261.11 EKX49176.1 - 0.058 13.1 0.6 0.34 10.7 0.2 2.5 2 0 0 2 2 2 0 Replication initiation and membrane attachment Peptidase_C48 PF02902.19 EKX49177.1 - 1.2e-05 25.3 0.0 2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain YqhG PF11079.8 EKX49177.1 - 0.11 11.5 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function DDE_Tnp_1_7 PF13843.6 EKX49178.1 - 5.2e-08 32.6 0.0 5.9e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 AAA_14 PF13173.6 EKX49181.1 - 0.03 14.4 0.0 0.07 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EKX49182.1 - 0.0053 16.8 4.1 0.0095 16.0 0.0 3.4 2 1 1 3 3 3 1 AAA domain FlhD PF05247.13 EKX49182.1 - 0.0073 16.5 1.7 81 3.6 0.0 4.2 4 0 0 4 4 4 0 Flagellar transcriptional activator (FlhD) AAA_11 PF13086.6 EKX49182.1 - 0.0082 16.0 0.0 0.0082 16.0 0.0 4.7 2 2 0 2 2 1 1 AAA domain AAA_30 PF13604.6 EKX49182.1 - 0.026 14.2 1.2 0.13 11.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 EKX49182.1 - 0.057 13.8 0.0 0.19 12.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 EKX49182.1 - 0.06 13.6 13.4 0.11 12.8 0.0 4.8 2 1 3 5 5 5 0 AAA domain AAA_7 PF12775.7 EKX49182.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 EKX49182.1 - 0.16 12.4 0.0 0.16 12.4 0.0 2.8 2 1 0 2 2 1 0 AAA ATPase domain DUF2877 PF11392.8 EKX49182.1 - 0.44 11.3 11.1 30 5.4 0.4 4.4 1 1 3 4 4 4 0 Protein of unknown function (DUF2877) ABC_tran PF00005.27 EKX49182.1 - 0.67 10.5 0.0 0.67 10.5 0.0 3.8 2 1 0 2 2 1 0 ABC transporter BORCS7 PF16088.5 EKX49182.1 - 1.2 9.5 18.5 3.2 8.1 1.4 4.3 1 1 3 4 4 4 0 BLOC-1-related complex sub-unit 7 FtsK_SpoIIIE PF01580.18 EKX49182.1 - 1.3 8.3 0.0 1.3 8.3 0.0 3.1 2 1 3 5 5 5 0 FtsK/SpoIIIE family RVT_1 PF00078.27 EKX49184.1 - 1.2e-07 31.5 0.0 1.9e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_14 PF13173.6 EKX49185.1 - 0.0057 16.7 0.0 0.0057 16.7 0.0 4.0 2 1 1 3 3 2 1 AAA domain AAA_11 PF13086.6 EKX49185.1 - 0.01 15.6 0.0 0.01 15.6 0.0 5.4 2 2 1 3 3 2 0 AAA domain BORCS7 PF16088.5 EKX49185.1 - 0.014 15.6 28.2 0.7 10.2 1.0 5.2 1 1 4 5 5 5 0 BLOC-1-related complex sub-unit 7 RNA_helicase PF00910.22 EKX49185.1 - 0.062 13.7 0.0 0.2 12.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase LAMTOR5 PF16672.5 EKX49185.1 - 0.074 13.0 0.4 3.3e+02 1.3 0.0 4.7 5 0 0 5 5 5 0 Ragulator complex protein LAMTOR5 AAA_22 PF13401.6 EKX49185.1 - 0.12 12.6 0.0 0.12 12.6 0.0 5.6 2 1 3 5 5 4 0 AAA domain AAA_7 PF12775.7 EKX49185.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 EKX49185.1 - 0.16 11.7 0.0 0.16 11.7 0.0 4.6 5 0 0 5 5 5 0 AAA domain AAA_16 PF13191.6 EKX49185.1 - 0.19 12.1 0.0 0.19 12.1 0.0 3.3 2 1 0 2 2 1 0 AAA ATPase domain ABC_tran PF00005.27 EKX49185.1 - 0.67 10.5 0.0 0.67 10.5 0.0 4.3 2 1 0 2 2 1 0 ABC transporter FtsK_SpoIIIE PF01580.18 EKX49185.1 - 1.4 8.2 0.0 1.4 8.2 0.0 4.8 2 1 4 6 6 6 0 FtsK/SpoIIIE family Snf7 PF03357.21 EKX49186.1 - 7.7e-08 32.1 10.6 1.4e-07 31.3 10.6 1.5 1 1 0 1 1 1 1 Snf7 Phosducin PF02114.16 EKX49186.1 - 0.022 13.7 1.9 0.032 13.2 1.9 1.2 1 0 0 1 1 1 0 Phosducin SURF2 PF05477.11 EKX49186.1 - 0.18 11.4 2.3 0.22 11.2 2.3 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF4094 PF13334.6 EKX49186.1 - 1.2 9.7 3.9 16 6.0 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) SRP_SPB PF02978.19 EKX49186.1 - 9.7 6.9 8.1 1.4e+02 3.2 0.0 2.8 1 1 1 2 2 2 0 Signal peptide binding domain 6PF2K PF01591.18 EKX49187.1 - 2.7e-68 229.6 0.3 4.7e-68 228.8 0.3 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EKX49187.1 - 1.1e-11 44.8 0.0 7.4e-11 42.1 0.0 2.4 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EKX49187.1 - 7.7e-08 32.6 0.2 2.5e-07 30.9 0.1 2.0 2 0 0 2 2 2 1 AAA domain CARD PF00619.21 EKX49187.1 - 0.0091 16.0 0.2 0.027 14.5 0.2 1.8 1 0 0 1 1 1 1 Caspase recruitment domain KTI12 PF08433.10 EKX49187.1 - 0.043 13.3 0.0 0.089 12.2 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ABC_membrane_2 PF06472.15 EKX49188.1 - 2.3e-47 161.7 3.3 2.9e-47 161.3 3.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EKX49188.1 - 1.4e-13 51.6 0.0 7.7e-13 49.1 0.0 2.1 1 1 0 1 1 1 1 ABC transporter SbmA_BacA PF05992.12 EKX49188.1 - 7e-09 35.5 6.4 1.4e-08 34.5 6.4 1.5 1 1 0 1 1 1 1 SbmA/BacA-like family NACHT PF05729.12 EKX49188.1 - 1.5e-05 25.0 0.1 3.6e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EKX49188.1 - 0.00029 21.3 0.3 0.00099 19.5 0.3 1.9 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EKX49188.1 - 0.0022 17.9 0.1 0.0039 17.1 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 EKX49188.1 - 0.016 14.9 0.0 0.038 13.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EKX49188.1 - 0.021 14.6 0.0 0.056 13.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 EKX49188.1 - 0.022 14.3 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EKX49188.1 - 0.053 14.0 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_membrane PF00664.23 EKX49188.1 - 0.073 12.7 8.7 0.17 11.5 8.7 1.6 1 1 0 1 1 1 0 ABC transporter transmembrane region AAA_22 PF13401.6 EKX49188.1 - 0.09 13.1 0.0 0.28 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EKX49188.1 - 0.15 11.7 0.0 0.66 9.7 0.0 2.0 3 0 0 3 3 3 0 IstB-like ATP binding protein Actin PF00022.19 EKX49190.1 - 0.028 13.0 0.3 0.027 13.1 0.3 1.2 1 0 0 1 1 1 0 Actin RR_TM4-6 PF06459.12 EKX49190.1 - 0.31 10.8 7.2 0.46 10.3 7.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EFTUD2 PF16004.5 EKX49190.1 - 0.64 10.6 9.1 0.11 13.1 4.9 1.8 2 1 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Presenilin PF01080.17 EKX49190.1 - 5.3 5.7 6.5 7 5.3 6.5 1.2 1 0 0 1 1 1 0 Presenilin Ion_trans_2 PF07885.16 EKX49191.1 - 2.1e-11 43.6 0.3 2.1e-11 43.6 0.3 3.4 5 0 0 5 5 5 1 Ion channel Lig_chan PF00060.26 EKX49191.1 - 5.9e-05 23.0 8.6 0.029 14.2 0.6 3.2 3 1 0 3 3 3 2 Ligand-gated ion channel SK_channel PF03530.14 EKX49191.1 - 0.0029 17.6 2.8 0.064 13.2 0.1 3.0 2 0 0 2 2 2 1 Calcium-activated SK potassium channel PRIMA1 PF16101.5 EKX49191.1 - 0.07 13.2 3.9 0.27 11.3 3.9 2.0 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Roughex PF06020.11 EKX49191.1 - 0.12 11.4 1.1 0.21 10.7 1.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein ABC_tran_CTD PF16326.5 EKX49191.1 - 0.14 12.4 5.3 2.7 8.3 0.4 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain RCC1 PF00415.18 EKX49192.1 - 5.5e-39 132.6 14.0 7.1e-13 49.0 0.0 5.1 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX49192.1 - 5.6e-33 112.1 9.6 2.9e-08 33.3 0.0 4.2 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat LysM PF01476.20 EKX49193.1 - 0.046 13.8 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 LysM domain CheZ PF04344.13 EKX49193.1 - 0.17 11.8 1.0 2.6 7.9 0.1 2.4 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ DASH_Dam1 PF08653.10 EKX49193.1 - 0.68 9.8 2.7 9.1 6.2 0.1 3.2 3 0 0 3 3 3 0 DASH complex subunit Dam1 AAA_11 PF13086.6 EKX49194.1 - 0.092 12.5 9.7 0.11 12.3 9.7 1.1 1 0 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.12 EKX49194.1 - 0.51 10.1 15.6 0.61 9.9 15.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Band_3_cyto PF07565.13 EKX49194.1 - 0.78 9.5 9.4 0.98 9.2 9.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PRTP PF01366.18 EKX49194.1 - 0.88 7.5 7.2 0.88 7.5 7.2 1.2 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Endostatin PF06482.11 EKX49194.1 - 1.3 8.4 6.3 1.4 8.3 6.3 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF87 PF01935.17 EKX49194.1 - 3.3 7.7 6.9 4.2 7.4 6.9 1.1 1 0 0 1 1 1 0 Helicase HerA, central domain Neur_chan_memb PF02932.16 EKX49194.1 - 8.7 6.3 7.2 10 6.1 7.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DDHD PF02862.17 EKX49194.1 - 9.9 6.2 8.0 12 6.0 8.0 1.1 1 0 0 1 1 1 0 DDHD domain UbiA PF01040.18 EKX49196.1 - 9.5e-29 100.4 6.6 1.6e-28 99.7 6.6 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family DUF3377 PF11857.8 EKX49196.1 - 5.3 7.0 6.1 20 5.2 0.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3377) GYF_2 PF14237.6 EKX49197.1 - 0.0016 18.2 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 GYF domain 2 Rab_eff_C PF04698.12 EKX49197.1 - 0.013 13.9 0.3 0.015 13.6 0.3 1.1 1 0 0 1 1 1 0 Rab effector MyRIP/melanophilin C-terminus DUF3435 PF11917.8 EKX49197.1 - 0.14 11.1 1.5 0.19 10.6 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) PRAI PF00697.22 EKX49198.1 - 0.074 12.8 0.0 0.43 10.3 0.0 1.9 1 1 1 2 2 2 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase TTL PF03133.15 EKX49199.1 - 1.2e-68 231.4 1.5 1.3e-68 231.3 1.5 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EKX49199.1 - 1e-08 34.8 1.4 1.7e-07 30.8 0.1 2.6 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EKX49199.1 - 6.9e-05 22.2 0.1 0.0013 18.1 0.0 2.2 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp RimK PF08443.11 EKX49199.1 - 0.092 12.3 0.0 0.21 11.2 0.0 1.6 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Ank_4 PF13637.6 EKX49201.1 - 2e-13 50.5 0.4 3.2e-09 37.1 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX49201.1 - 3.3e-12 46.4 0.0 8.6e-12 45.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX49201.1 - 4e-10 40.2 0.0 9.7e-10 38.9 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX49201.1 - 4.9e-07 29.6 0.3 4.9e-05 23.4 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EKX49201.1 - 6.1e-07 29.6 0.0 0.001 19.4 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeat BLACT_WH PF17778.1 EKX49201.1 - 0.036 14.1 0.1 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain UPF0242 PF06785.11 EKX49202.1 - 0.071 13.2 2.5 0.14 12.2 2.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HSCB_C PF07743.13 EKX49202.1 - 0.22 12.1 2.5 1.4 9.5 1.3 2.4 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain ZapB PF06005.12 EKX49202.1 - 0.26 11.7 6.0 0.6 10.6 6.0 1.5 1 0 0 1 1 1 0 Cell division protein ZapB SUI1 PF01253.22 EKX49203.1 - 0.12 12.9 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor SUI1 Roc PF08477.13 EKX49206.1 - 4.5e-14 52.7 0.0 1.4e-13 51.1 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TIR_2 PF13676.6 EKX49206.1 - 4.7e-13 49.8 0.1 7.5e-12 45.9 0.0 2.6 2 0 0 2 2 2 1 TIR domain COR PF16095.5 EKX49206.1 - 3.1e-11 43.5 0.1 1.4e-06 28.3 0.1 2.6 2 1 0 2 2 2 2 C-terminal of Roc, COR, domain Ras PF00071.22 EKX49206.1 - 2.4e-07 30.5 0.0 1.7e-06 27.7 0.0 2.1 1 1 0 1 1 1 1 Ras family Arf PF00025.21 EKX49206.1 - 7.4e-05 22.3 0.1 0.00019 20.9 0.1 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family EF-hand_7 PF13499.6 EKX49206.1 - 0.0025 18.2 0.2 0.019 15.4 0.2 2.6 1 0 0 1 1 1 1 EF-hand domain pair GTP_EFTU PF00009.27 EKX49206.1 - 0.0036 16.9 0.0 0.01 15.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EKX49206.1 - 0.013 15.6 0.0 0.067 13.3 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EKX49206.1 - 0.05 13.0 0.0 0.091 12.1 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EKX49206.1 - 0.18 10.9 0.0 0.35 10.0 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit Zip PF02535.22 EKX49207.1 - 2.4e-23 82.9 16.5 4.5e-21 75.4 4.4 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter E1-E2_ATPase PF00122.20 EKX49207.1 - 1.2 8.7 7.5 3.2 7.2 0.3 2.7 2 1 1 3 3 3 0 E1-E2 ATPase EMC3_TMCO1 PF01956.16 EKX49208.1 - 0.17 11.6 0.7 0.45 10.2 0.7 1.7 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like PHM7_cyt PF14703.6 EKX49208.1 - 4.3 7.5 7.2 7 6.8 0.0 2.4 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF5385 PF17359.2 EKX49209.1 - 1.5 8.3 4.9 2.9 7.4 4.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Beta_helix PF13229.6 EKX49210.1 - 9.1e-05 22.4 0.0 0.00015 21.7 0.0 1.2 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 EKX49210.1 - 0.0096 15.2 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Cwf_Cwc_15 PF04889.12 EKX49210.1 - 0.015 15.1 8.2 0.025 14.3 8.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GCIP PF13324.6 EKX49210.1 - 0.07 12.7 3.6 0.11 12.1 3.6 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF2457 PF10446.9 EKX49210.1 - 0.083 12.0 5.6 0.11 11.6 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) ApeC PF16977.5 EKX49210.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain of apextrin Fimbrillin_C PF15495.6 EKX49210.1 - 0.18 12.2 0.1 0.37 11.2 0.1 1.4 1 0 0 1 1 1 0 Major fimbrial subunit protein type IV, Fimbrillin, C-terminal CENP-B_dimeris PF09026.10 EKX49210.1 - 0.22 11.9 14.7 0.043 14.2 10.7 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NOA36 PF06524.12 EKX49210.1 - 0.27 10.5 7.0 0.5 9.6 7.0 1.5 1 0 0 1 1 1 0 NOA36 protein DUF4611 PF15387.6 EKX49210.1 - 1.9 8.8 6.2 4.8 7.5 6.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 EKX49210.1 - 2 6.4 5.8 2.5 6.1 5.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 EKX49210.1 - 2 6.6 3.9 2.8 6.1 3.9 1.2 1 0 0 1 1 1 0 CDC45-like protein dsrm PF00035.26 EKX49212.1 - 2.9e-11 43.9 0.1 5.6e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 EKX49212.1 - 0.0012 19.1 0.0 0.0026 18.0 0.0 1.6 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 Dicer_dimer PF03368.14 EKX49212.1 - 0.047 13.8 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Dicer dimerisation domain PIN7 PF18475.1 EKX49212.1 - 0.097 13.3 0.0 0.27 11.9 0.0 1.7 1 0 0 1 1 1 0 PIN domain PAN_4 PF14295.6 EKX49214.1 - 0.27 11.2 5.2 0.57 10.1 5.2 1.5 1 0 0 1 1 1 0 PAN domain RAP PF08373.10 EKX49216.1 - 5.8e-10 39.1 0.1 6.6e-09 35.7 0.0 2.3 2 0 0 2 2 2 1 RAP domain FAST_1 PF06743.15 EKX49216.1 - 0.00032 20.6 0.0 0.27 11.2 0.0 4.0 4 0 0 4 4 4 1 FAST kinase-like protein, subdomain 1 MTES_1575 PF18741.1 EKX49216.1 - 0.0059 16.7 0.2 0.25 11.5 0.0 2.8 2 0 0 2 2 2 1 REase_MTES_1575 Mito_carr PF00153.27 EKX49217.1 - 1.6e-40 136.9 4.9 1.7e-15 56.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PIGA PF08288.12 EKX49218.1 - 2.5e-37 127.4 0.7 6.9e-37 125.9 0.1 2.1 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 EKX49218.1 - 1.6e-26 93.3 0.1 2.6e-26 92.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EKX49218.1 - 1e-25 90.2 0.0 1.7e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EKX49218.1 - 3.3e-23 82.6 0.5 9.5e-23 81.1 0.1 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EKX49218.1 - 2.9e-09 37.6 0.0 4.8e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EKX49218.1 - 0.016 15.6 0.1 0.055 13.9 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferases group 1 PDZ_6 PF17820.1 EKX49219.1 - 2.1e-07 30.6 0.0 4.7e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX49219.1 - 2.7e-05 24.4 0.0 4.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX49219.1 - 0.013 15.8 0.0 0.038 14.3 0.0 1.8 2 1 0 2 2 2 0 PDZ domain PH PF00169.29 EKX49220.1 - 0.00016 22.1 0.0 0.00064 20.2 0.0 2.1 1 1 0 1 1 1 1 PH domain Phage_TAC_11 PF11836.8 EKX49220.1 - 0.032 14.3 0.1 0.45 10.7 0.0 2.7 2 1 0 2 2 2 0 Phage tail tube protein, GTA-gp10 EcoR124_C PF12008.8 EKX49220.1 - 0.047 13.3 2.5 0.058 13.0 0.9 1.8 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal SR-25 PF10500.9 EKX49221.1 - 0.15 11.6 22.9 0.2 11.3 22.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Vfa1 PF08432.10 EKX49221.1 - 0.19 12.1 19.8 0.25 11.6 19.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDHD PF02862.17 EKX49221.1 - 1.5 8.9 7.9 1.7 8.7 7.9 1.1 1 0 0 1 1 1 0 DDHD domain TIMELESS PF04821.14 EKX49221.1 - 2.2 7.5 11.0 3.2 6.9 11.0 1.4 1 1 0 1 1 1 0 Timeless protein RR_TM4-6 PF06459.12 EKX49221.1 - 2.8 7.7 17.4 3.5 7.4 17.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_11 PF13086.6 EKX49221.1 - 5.4 6.7 15.3 6.2 6.5 15.3 1.1 1 0 0 1 1 1 0 AAA domain Ureide_permease PF07168.11 EKX49221.1 - 6.4 5.4 4.8 9.6 4.8 4.8 1.3 1 0 0 1 1 1 0 Ureide permease CDC45 PF02724.14 EKX49221.1 - 6.9 4.8 18.8 7.9 4.6 18.8 1.0 1 0 0 1 1 1 0 CDC45-like protein EOS1 PF12326.8 EKX49221.1 - 9.3 6.1 11.6 13 5.7 11.5 1.3 1 1 0 1 1 1 0 N-glycosylation protein DSPc PF00782.20 EKX49223.1 - 2.6e-25 88.8 0.0 2.8e-25 88.6 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 EKX49223.1 - 0.0031 17.2 0.1 0.0037 17.0 0.1 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 EKX49223.1 - 0.0087 15.7 0.0 0.0097 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase zf-C4 PF00105.18 EKX49224.1 - 0.0087 16.5 2.9 3.7 8.1 0.2 2.6 2 0 0 2 2 2 2 Zinc finger, C4 type (two domains) DUF4508 PF14969.6 EKX49224.1 - 0.0088 16.3 1.3 3 8.1 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4508) SapA PF02199.15 EKX49224.1 - 0.049 13.9 1.4 12 6.3 0.1 2.4 2 0 0 2 2 2 0 Saposin A-type domain FliG_C PF01706.16 EKX49224.1 - 0.056 13.6 1.1 13 6.0 0.1 2.7 2 0 0 2 2 2 0 FliG C-terminal domain Suppressor_APC PF11414.8 EKX49224.1 - 0.073 13.2 2.7 9.5 6.4 0.2 2.8 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein Peptidase_M9_N PF08453.10 EKX49224.1 - 0.25 11.0 1.9 14 5.4 0.1 3.0 3 0 0 3 3 3 0 Peptidase family M9 N-terminal CAP-ZIP_m PF15255.6 EKX49224.1 - 1.2 9.4 4.8 30 4.9 0.2 3.2 3 0 0 3 3 3 0 WASH complex subunit CAP-Z interacting, central region Arf PF00025.21 EKX49225.1 - 6e-44 149.6 0.0 7.4e-44 149.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EKX49225.1 - 1.6e-12 47.2 0.1 2.1e-12 46.9 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EKX49225.1 - 3.7e-06 27.1 0.1 5.7e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EKX49225.1 - 4.5e-05 23.1 0.0 5.9e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EKX49225.1 - 0.00022 20.5 2.1 0.45 9.6 0.0 2.5 2 1 0 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 EKX49225.1 - 0.00042 20.4 0.0 0.00057 19.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EKX49225.1 - 0.0014 18.0 0.1 0.0019 17.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region NACHT PF05729.12 EKX49225.1 - 0.0091 15.9 0.6 0.11 12.4 0.6 2.1 1 1 0 1 1 1 1 NACHT domain AAA_29 PF13555.6 EKX49225.1 - 0.026 14.3 0.1 0.048 13.4 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 EKX49225.1 - 0.16 12.0 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EKX49225.1 - 0.16 12.3 0.2 23 5.3 0.0 2.3 1 1 0 2 2 2 0 AAA ATPase domain ABC1 PF03109.16 EKX49226.1 - 7.1e-24 84.3 0.0 3.6e-23 82.0 0.0 2.0 2 0 0 2 2 2 1 ABC1 family APH PF01636.23 EKX49226.1 - 2.8e-06 27.4 0.7 2.8e-06 27.4 0.7 3.3 2 2 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.25 EKX49226.1 - 0.0024 17.3 0.0 0.045 13.1 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain RIO1 PF01163.22 EKX49226.1 - 0.016 14.8 0.0 0.24 11.0 0.0 2.2 2 0 0 2 2 2 0 RIO1 family PolyA_pol_RNAbd PF12627.7 EKX49226.1 - 0.15 11.9 2.2 0.26 11.1 0.0 2.7 3 0 0 3 3 3 0 Probable RNA and SrmB- binding site of polymerase A Hist_deacetyl PF00850.19 EKX49227.1 - 5.3e-43 147.6 0.6 9.8e-43 146.8 0.6 1.4 1 1 0 1 1 1 1 Histone deacetylase domain Methyltransf_16 PF10294.9 EKX49228.1 - 3.4e-13 49.7 1.0 1.3e-12 47.8 0.2 2.1 2 0 0 2 2 2 1 Lysine methyltransferase TPR_2 PF07719.17 EKX49228.1 - 3.3e-09 36.2 5.6 0.012 15.6 0.1 3.8 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX49228.1 - 3.7e-05 23.3 2.4 0.24 11.3 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX49228.1 - 0.0078 17.0 4.7 11 7.2 0.1 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX49228.1 - 0.01 16.4 5.1 0.18 12.5 1.9 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Cons_hypoth95 PF03602.15 EKX49228.1 - 0.058 13.0 1.1 0.18 11.5 0.1 2.3 3 0 0 3 3 3 0 Conserved hypothetical protein 95 PrmA PF06325.13 EKX49228.1 - 0.1 12.0 0.1 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) TPR_10 PF13374.6 EKX49228.1 - 0.36 10.8 5.4 9.8 6.2 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX49228.1 - 0.41 11.0 2.9 16 6.0 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX49228.1 - 0.51 10.7 10.1 7.6 6.9 5.5 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat ADH_zinc_N PF00107.26 EKX49229.1 - 6.2e-27 94.1 0.0 1.2e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EKX49229.1 - 2e-16 61.2 0.0 4.2e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EKX49229.1 - 7.7e-08 32.2 1.0 1.3e-06 28.3 0.3 2.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EKX49229.1 - 2.5e-06 27.3 1.0 1.3e-05 25.1 0.1 2.2 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase TrkA_N PF02254.18 EKX49229.1 - 0.021 15.1 0.1 0.039 14.2 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Dpy-30 PF05186.13 EKX49230.1 - 0.0086 15.7 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif RIIa PF02197.17 EKX49230.1 - 0.26 11.0 1.9 0.87 9.3 1.5 2.2 1 1 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Cornichon PF03311.14 EKX49231.1 - 1.8e-05 25.1 0.7 3.2e-05 24.2 0.7 1.7 1 1 0 1 1 1 1 Cornichon protein IQ PF00612.27 EKX49234.1 - 2e-06 27.1 40.0 0.0066 16.1 0.1 7.2 7 0 0 7 7 7 6 IQ calmodulin-binding motif DNA_meth_N PF18284.1 EKX49234.1 - 4.6 7.2 10.5 0.47 10.4 1.0 3.3 2 1 2 4 4 4 0 DNA methylase N-terminal domain PrmC_N PF17827.1 EKX49235.1 - 0.13 12.9 0.0 0.14 12.7 0.0 1.2 1 0 0 1 1 1 0 PrmC N-terminal domain FtsH_ext PF06480.15 EKX49236.1 - 0.0019 18.6 0.0 0.0027 18.0 0.0 1.3 1 0 0 1 1 1 1 FtsH Extracellular Cys_box PF17869.1 EKX49236.1 - 0.029 14.5 2.8 0.056 13.6 2.8 1.4 1 0 0 1 1 1 0 Anosmin cysteine rich domain Pkinase PF00069.25 EKX49238.1 - 1.3e-64 218.1 0.0 1.6e-64 217.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX49238.1 - 2.5e-36 125.3 0.0 3.4e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX49238.1 - 8.3e-06 24.8 0.0 1.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EKX49238.1 - 0.001 18.5 0.0 0.005 16.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 EKX49238.1 - 0.0042 16.7 0.2 0.89 9.1 0.0 2.1 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.20 EKX49238.1 - 0.028 14.0 0.1 3.5 7.2 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase APH PF01636.23 EKX49238.1 - 0.036 14.0 0.0 0.78 9.6 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family IMPDH PF00478.25 EKX49239.1 - 5.7e-82 275.5 0.7 8.3e-82 274.9 0.7 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EKX49239.1 - 0.00083 18.5 4.5 0.00083 18.5 4.5 1.6 1 1 1 2 2 2 1 FMN-dependent dehydrogenase Aldolase PF01081.19 EKX49239.1 - 0.035 13.5 0.4 0.14 11.6 0.1 2.0 1 1 1 2 2 2 0 KDPG and KHG aldolase Gly_acyl_tr_C PF08444.10 EKX49239.1 - 0.13 12.6 0.0 0.43 10.9 0.0 1.9 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region tRNA-synt_2d PF01409.20 EKX49240.1 - 8.4e-90 300.5 0.1 1.1e-89 300.2 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 EKX49240.1 - 3.8e-16 59.1 0.6 9.5e-16 57.8 0.6 1.7 1 0 0 1 1 1 1 PheRS DNA binding domain 3 PheRS_DBD1 PF18552.1 EKX49240.1 - 4.1e-09 36.0 0.2 1.1e-08 34.7 0.1 1.8 2 0 0 2 2 2 1 PheRS DNA binding domain 1 tRNA_synthFbeta PF17759.1 EKX49240.1 - 3.9e-08 33.0 0.0 1.1e-06 28.2 0.0 2.6 1 1 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 EKX49240.1 - 0.00015 21.0 0.1 0.003 16.7 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 EKX49240.1 - 0.0075 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) PheRS_DBD2 PF18554.1 EKX49240.1 - 0.026 14.5 4.3 0.084 12.9 4.3 2.0 1 1 0 1 1 1 0 PheRS DNA binding domain 2 OapA PF04225.12 EKX49240.1 - 0.11 12.7 0.1 16 5.7 0.0 2.8 2 0 0 2 2 2 0 Opacity-associated protein A LysM-like domain LRR_9 PF14580.6 EKX49242.1 - 7e-12 45.2 0.1 1.3e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EKX49242.1 - 1.6e-08 34.7 17.7 1.1e-06 28.8 2.6 3.4 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX49242.1 - 0.00053 19.7 7.1 0.00055 19.6 4.3 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 EKX49242.1 - 0.001 18.9 4.0 0.25 11.5 0.6 3.4 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 EKX49242.1 - 0.0036 17.7 3.0 21 6.2 0.7 4.0 3 0 0 3 3 3 0 Leucine Rich Repeat Prominin PF05478.11 EKX49242.1 - 0.12 10.4 2.3 0.18 9.7 2.3 1.2 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.12 EKX49242.1 - 0.32 11.0 2.8 0.82 9.7 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF5595 PF18077.1 EKX49242.1 - 4 7.6 8.0 0.18 11.9 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) KxDL PF10241.9 EKX49242.1 - 9.2 6.6 11.4 8.5 6.7 0.9 3.0 2 0 0 2 2 2 0 Uncharacterized conserved protein DAGK_acc PF00609.19 EKX49244.1 - 1.8e-39 135.6 0.0 2.6e-38 131.9 0.0 2.1 1 1 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 EKX49244.1 - 2.8e-19 69.0 0.3 4.5e-19 68.3 0.3 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain CHB_HEX_C_1 PF13290.6 EKX49245.1 - 7.2e-274 884.4 127.7 6.5e-20 70.9 1.0 23.7 23 2 1 24 24 24 22 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 EKX49245.1 - 4.5e-241 779.3 97.0 1.3e-15 57.3 0.0 23.5 22 2 1 23 23 23 22 Fn3 associated CHB_HEX_C PF03174.13 EKX49245.1 - 2.6e-61 203.6 30.8 0.0003 20.7 0.0 20.0 21 0 0 21 21 21 16 Chitobiase/beta-hexosaminidase C-terminal domain LCCL PF03815.19 EKX49245.1 - 3e-13 49.7 0.0 9.6e-13 48.1 0.0 1.8 1 0 0 1 1 1 1 LCCL domain DUF5110 PF17137.4 EKX49245.1 - 0.021 15.1 0.1 17 5.7 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5110) Lactamase_B_2 PF12706.7 EKX49246.1 - 2.3e-38 131.7 0.0 4e-38 130.9 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EKX49246.1 - 4.8e-15 55.8 0.0 1e-14 54.8 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EKX49246.1 - 7.2e-06 26.1 0.0 2.7e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily B3 PF02362.21 EKX49246.1 - 0.061 13.2 0.1 0.41 10.5 0.0 2.4 2 1 0 2 2 2 0 B3 DNA binding domain TPR_19 PF14559.6 EKX49247.1 - 0.074 13.6 1.1 0.46 11.0 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX49248.1 - 0.074 13.6 1.1 0.46 11.0 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 EKX49250.1 - 9.7e-66 221.8 0.0 1.6e-59 201.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EKX49250.1 - 1.4e-32 113.0 0.0 3e-32 111.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX49250.1 - 0.12 11.7 0.1 0.33 10.3 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5320 PF17253.2 EKX49250.1 - 0.65 11.1 8.0 2.2 9.4 8.0 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5320) PDZ_6 PF17820.1 EKX49251.1 - 1.6e-10 40.7 0.3 3.8e-10 39.5 0.3 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX49251.1 - 6.1e-08 32.9 0.0 1.4e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX49251.1 - 3.1e-05 24.2 0.1 0.00017 21.9 0.0 2.2 2 0 0 2 2 2 1 PDZ domain Fungal_TACC PF12709.7 EKX49251.1 - 0.013 15.9 2.5 0.013 15.9 2.5 3.6 1 1 3 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins Mitofilin PF09731.9 EKX49251.1 - 0.085 11.7 34.4 0.46 9.3 18.9 2.1 1 1 1 2 2 2 0 Mitochondrial inner membrane protein V-ATPase_G_2 PF16999.5 EKX49251.1 - 0.092 13.2 23.7 0.22 12.0 5.9 3.2 1 1 2 3 3 3 0 Vacuolar (H+)-ATPase G subunit YbjQ_1 PF01906.17 EKX49251.1 - 0.16 12.6 6.4 4.2 8.1 0.5 2.9 1 1 2 3 3 3 0 Putative heavy-metal-binding Remorin_C PF03763.13 EKX49251.1 - 3 7.8 24.3 3.4 7.6 5.5 3.4 1 1 2 3 3 3 0 Remorin, C-terminal region RB_A PF01858.17 EKX49251.1 - 4.2 7.2 11.8 12 5.7 1.2 2.2 1 1 1 2 2 2 0 Retinoblastoma-associated protein A domain Baculo_PEP_C PF04513.12 EKX49251.1 - 4.5 7.3 9.3 5.2 7.1 3.5 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ocnus PF05005.15 EKX49252.1 - 2e-30 105.1 0.9 2.3e-30 104.9 0.9 1.0 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) HNOB PF07700.15 EKX49253.1 - 0.14 12.1 0.1 35 4.3 0.0 3.4 4 0 0 4 4 4 0 Haem-NO-binding DUF2358 PF10184.9 EKX49254.1 - 2.2e-10 40.8 0.0 9e-10 38.8 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) EF-hand_5 PF13202.6 EKX49254.1 - 0.00022 20.6 0.1 0.0004 19.7 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 EKX49254.1 - 0.00079 18.8 0.1 0.0015 17.9 0.1 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EKX49254.1 - 0.0019 18.0 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 EKX49254.1 - 0.023 14.6 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_7 PF13499.6 EKX49254.1 - 0.094 13.2 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair MMU163 PF17119.5 EKX49254.1 - 0.18 10.9 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis DRMBL PF07522.14 EKX49255.1 - 6.9e-05 23.0 0.3 0.00023 21.3 0.3 1.9 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase DUF4286 PF14114.6 EKX49255.1 - 0.012 16.1 0.1 8 7.0 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) Lactamase_B PF00753.27 EKX49255.1 - 0.16 12.0 0.1 0.3 11.1 0.1 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily SPRY PF00622.28 EKX49257.1 - 1.3e-10 41.4 0.9 4e-09 36.6 0.9 2.2 1 1 0 1 1 1 1 SPRY domain Ribosomal_L22 PF00237.19 EKX49258.1 - 0.019 15.2 0.1 0.048 13.9 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e DUF4710 PF15828.5 EKX49258.1 - 0.62 10.2 5.4 1.3 9.2 0.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) Elong_Iki1 PF10483.9 EKX49259.1 - 2e-07 30.9 0.1 9.6e-06 25.3 0.1 2.1 1 1 0 1 1 1 1 Elongator subunit Iki1 NAD_binding_10 PF13460.6 EKX49261.1 - 3.5e-23 82.5 0.6 1.3e-22 80.6 0.6 1.8 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EKX49261.1 - 1.5e-08 34.0 0.1 3.1e-08 32.9 0.1 1.6 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EKX49261.1 - 5e-08 32.7 0.0 8.6e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EKX49261.1 - 2.2e-06 27.4 0.1 3.8e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 EKX49261.1 - 0.00013 21.2 0.1 0.00019 20.7 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EKX49261.1 - 0.00067 18.8 0.2 0.0011 18.2 0.2 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 EKX49261.1 - 0.082 12.3 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Semialdhyde_dh PF01118.24 EKX49261.1 - 0.13 12.7 0.2 0.43 11.0 0.1 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain CTX_RstB PF07459.11 EKX49262.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.7 2 0 0 2 2 2 0 CTX phage RstB protein DUF383 PF04063.14 EKX49263.1 - 3.2e-21 75.9 0.0 4.4e-19 68.9 0.0 2.8 1 1 2 3 3 3 2 Domain of unknown function (DUF383) DUF384 PF04064.13 EKX49263.1 - 3.9e-14 52.2 1.7 2.6e-13 49.6 0.1 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF384) DUF1722 PF08349.11 EKX49263.1 - 0.18 12.1 0.0 0.39 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) FAD-oxidase_C PF02913.19 EKX49264.1 - 4.1e-55 187.1 0.0 5.4e-55 186.7 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EKX49264.1 - 1.1e-36 125.6 0.6 2.4e-36 124.5 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain Sterol_MT_C PF08498.10 EKX49264.1 - 0.15 12.4 0.0 40 4.6 0.0 3.0 3 0 0 3 3 3 0 Sterol methyltransferase C-terminal TPR_2 PF07719.17 EKX49265.1 - 1.7e-05 24.6 3.6 0.031 14.4 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX49265.1 - 2.4e-05 23.9 3.5 0.17 11.8 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TAF4 PF05236.14 EKX49265.1 - 0.011 15.5 2.5 0.012 15.4 2.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family TIP120 PF08623.10 EKX49265.1 - 0.068 12.9 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) TPR_11 PF13414.6 EKX49265.1 - 0.19 11.4 1.0 9.6 6.0 0.0 3.0 4 0 0 4 4 4 0 TPR repeat TPR_8 PF13181.6 EKX49265.1 - 0.19 12.0 0.2 0.19 12.0 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX49265.1 - 0.77 10.3 0.0 0.77 10.3 0.0 3.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX49265.1 - 1.6 9.7 5.4 3.7 8.6 0.2 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat Mg_trans_NIPA PF05653.14 EKX49266.1 - 3.9e-15 55.7 9.0 3.2e-14 52.8 2.4 2.3 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 EKX49266.1 - 0.0028 17.8 1.8 0.0028 17.8 1.8 3.0 4 0 0 4 4 4 1 EamA-like transporter family Glycos_transf_2 PF00535.26 EKX49267.1 - 1.2e-15 57.7 0.0 1.6e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EKX49267.1 - 5.8e-08 32.9 0.0 6.7e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EKX49267.1 - 0.001 18.6 0.0 0.0014 18.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 EKX49267.1 - 0.065 13.8 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 zf-C3HC4_3 PF13920.6 EKX49269.1 - 7e-10 38.6 5.6 1.4e-09 37.6 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX49269.1 - 2.2e-08 34.3 9.1 4.7e-08 33.2 9.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX49269.1 - 3.8e-05 23.5 8.7 7.8e-05 22.4 8.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX49269.1 - 4.2e-05 23.3 7.9 8.6e-05 22.3 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX49269.1 - 4.7e-05 23.2 6.0 0.00011 21.9 6.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EKX49269.1 - 0.024 14.6 7.4 0.036 14.0 6.5 1.8 1 1 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 EKX49269.1 - 0.5 10.7 8.4 1.4 9.3 8.4 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EKX49269.1 - 0.52 10.4 7.4 1.1 9.4 7.4 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Pkinase PF00069.25 EKX49270.1 - 1.5e-69 234.3 0.0 1.9e-69 234.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX49270.1 - 1.8e-41 142.2 0.0 2.1e-41 141.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX49270.1 - 4e-07 29.6 0.0 1.2e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EKX49270.1 - 0.00032 19.8 0.4 0.00045 19.3 0.4 1.3 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EKX49270.1 - 0.00055 19.9 0.1 0.049 13.5 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EKX49270.1 - 0.0058 16.2 0.6 0.022 14.3 0.6 1.8 1 1 0 1 1 1 1 RIO1 family YukC PF10140.9 EKX49270.1 - 0.0065 15.3 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Seadorna_VP7 PF07387.11 EKX49270.1 - 0.041 12.9 0.0 0.059 12.4 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.11 EKX49270.1 - 0.089 11.7 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TraI_2B PF18340.1 EKX49270.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 DNA relaxase TraI 2B/2B-like domain Sulf_transp PF04143.14 EKX49271.1 - 1.7e-33 116.5 28.5 2e-33 116.3 28.5 1.0 1 0 0 1 1 1 1 Sulphur transport ClpS PF02617.17 EKX49272.1 - 2e-10 40.3 0.3 9.7e-10 38.1 0.2 2.3 2 1 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS Sacchrp_dh_NADP PF03435.18 EKX49272.1 - 1.1e-07 32.1 0.0 5.1e-07 30.0 0.0 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain APG17 PF04108.12 EKX49272.1 - 0.045 12.9 0.1 0.062 12.4 0.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 DUF4110 PF13422.6 EKX49273.1 - 0.019 15.0 5.1 0.019 15.0 5.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4110) NifQ PF04891.12 EKX49273.1 - 0.33 11.3 4.1 0.29 11.5 2.4 1.7 1 1 1 2 2 2 0 NifQ PPP4R2 PF09184.11 EKX49273.1 - 5.7 6.4 19.4 7.8 6.0 19.4 1.1 1 0 0 1 1 1 0 PPP4R2 Nucleo_P87 PF07267.11 EKX49273.1 - 7.1 5.3 15.0 9.8 4.9 15.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SpoU_methylase PF00588.19 EKX49274.1 - 1e-21 77.6 0.0 3.6e-21 75.8 0.0 1.8 2 0 0 2 2 2 1 SpoU rRNA Methylase family DUF4061 PF13270.6 EKX49275.1 - 0.027 14.8 0.8 0.29 11.5 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) CDH1_2_SANT_HL1 PF18375.1 EKX49275.1 - 0.066 13.9 1.5 0.36 11.5 0.6 2.5 3 0 0 3 3 3 0 CDH1/2 SANT-Helical linker 1 HSCB_C PF07743.13 EKX49275.1 - 0.33 11.5 4.3 7.2 7.2 1.3 3.3 4 0 0 4 4 4 0 HSCB C-terminal oligomerisation domain NatB_MDM20 PF09797.9 EKX49276.1 - 2.4e-37 128.8 1.3 3.1e-36 125.1 0.0 2.6 3 0 0 3 3 3 1 N-acetyltransferase B complex (NatB) non catalytic subunit ANAPC3 PF12895.7 EKX49276.1 - 5.5e-06 26.5 3.2 0.11 12.7 0.1 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EKX49276.1 - 8.9e-06 26.1 14.4 0.0095 16.4 2.6 4.5 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX49276.1 - 3.5e-05 24.3 10.3 3.8 8.6 0.2 6.6 5 1 2 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX49276.1 - 5.8e-05 22.9 5.1 0.61 10.3 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX49276.1 - 0.0002 21.6 6.1 0.1 12.9 0.4 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX49276.1 - 0.00026 20.8 1.4 13 6.0 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 EKX49276.1 - 0.00029 21.2 0.1 12 6.9 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX49276.1 - 0.0017 18.2 4.7 20 5.2 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EKX49276.1 - 0.0076 16.0 0.4 10 6.1 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR_2 PF13041.6 EKX49276.1 - 0.018 15.2 0.5 77 3.6 0.0 4.4 4 0 0 4 4 4 0 PPR repeat family TPR_8 PF13181.6 EKX49276.1 - 0.036 14.3 3.7 12 6.4 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 EKX49276.1 - 0.045 14.4 8.2 2.1 9.0 1.6 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_5 PF12688.7 EKX49276.1 - 0.22 11.8 2.5 0.43 10.8 0.7 2.4 2 0 0 2 2 2 0 Tetratrico peptide repeat Med14 PF08638.11 EKX49277.1 - 1.4e-35 122.5 3.6 2.6e-35 121.6 3.6 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 CHB_HEX_C_1 PF13290.6 EKX49278.1 - 3.6e-12 46.1 1.6 4.3e-10 39.5 0.0 3.1 2 1 0 2 2 2 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 EKX49278.1 - 1.6e-11 44.2 0.6 8.8e-11 41.8 0.0 2.5 2 0 0 2 2 2 1 Fn3 associated PA14 PF07691.12 EKX49278.1 - 0.0014 18.4 0.0 0.082 12.7 0.0 2.4 2 0 0 2 2 2 1 PA14 domain Filamin PF00630.19 EKX49278.1 - 0.0018 19.1 0.0 8.3 7.3 0.0 4.7 3 2 0 3 3 3 1 Filamin/ABP280 repeat Dynactin_p22 PF07426.11 EKX49280.1 - 4.3e-07 29.9 1.7 6.9e-05 22.8 1.7 2.9 1 1 0 1 1 1 1 Dynactin subunit p22 Mistic PF11458.8 EKX49280.1 - 0.029 14.3 0.0 7.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Membrane-integrating protein Mistic WD40 PF00400.32 EKX49281.1 - 0.16 12.9 3.0 35 5.5 0.1 3.8 3 1 0 3 3 3 0 WD domain, G-beta repeat Methyltransf_4 PF02390.17 EKX49282.1 - 1.7e-49 167.6 0.0 2.1e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 EKX49282.1 - 0.00013 22.6 0.0 0.00026 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX49282.1 - 0.001 19.8 0.0 0.003 18.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EKX49282.1 - 0.005 16.4 0.0 0.014 14.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EKX49282.1 - 0.0084 16.7 0.0 0.06 14.0 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.13 EKX49282.1 - 0.042 13.4 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 EKX49282.1 - 0.087 12.6 0.1 0.15 11.8 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 EKX49282.1 - 0.094 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MIP PF00230.20 EKX49283.1 - 9.6e-46 156.3 17.9 1.3e-45 155.9 17.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF485 PF04341.12 EKX49283.1 - 0.56 10.2 3.7 0.73 9.8 1.7 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF485 DUF4407 PF14362.6 EKX49284.1 - 0.005 16.2 3.4 0.0077 15.6 3.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Enoyl_reductase PF12241.8 EKX49284.1 - 0.029 13.7 1.6 3 7.1 0.3 2.3 2 0 0 2 2 2 0 Trans-2-enoyl-CoA reductase catalytic region DivIC PF04977.15 EKX49284.1 - 0.11 12.3 6.3 1.1 9.0 0.7 2.4 2 0 0 2 2 2 0 Septum formation initiator TMF_TATA_bd PF12325.8 EKX49284.1 - 0.48 10.7 11.0 0.34 11.2 3.0 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding TetR_C_23 PF17931.1 EKX49284.1 - 0.93 9.6 4.4 16 5.6 0.5 2.7 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain APG6_N PF17675.1 EKX49284.1 - 1.7 9.1 20.8 1.1 9.8 7.7 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region BBS2_C PF14782.6 EKX49284.1 - 2 7.1 11.0 1.7 7.3 2.7 2.4 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal GAS PF13851.6 EKX49284.1 - 2.2 7.6 11.3 4.9 6.5 2.1 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.20 EKX49284.1 - 8.5 6.4 11.5 13 5.8 2.8 2.5 2 0 0 2 2 2 0 Prefoldin subunit Metallophos PF00149.28 EKX49285.1 - 6.2e-17 62.8 0.9 3.2e-09 37.6 0.6 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 EKX49285.1 - 2.6e-13 50.3 0.0 7.4e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PA PF02225.22 EKX49285.1 - 1.2e-06 28.4 0.0 3.6e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 PA domain Metallophos_C PF14008.6 EKX49285.1 - 0.00059 20.6 0.5 0.01 16.7 0.0 3.0 3 0 0 3 3 3 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 EKX49285.1 - 0.012 15.9 0.0 6.8 6.9 0.0 2.6 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain PhoD_N PF16655.5 EKX49285.1 - 0.074 13.6 0.1 0.36 11.4 0.0 2.1 2 0 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain DUF4355 PF14265.6 EKX49287.1 - 1.9 8.7 10.3 0.16 12.2 4.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Ion_trans PF00520.31 EKX49288.1 - 1.6e-14 53.8 14.7 2.5e-14 53.1 14.7 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX49288.1 - 9.9e-13 47.9 0.5 2.7e-12 46.5 0.5 1.7 1 0 0 1 1 1 1 Ion channel cNMP_binding PF00027.29 EKX49288.1 - 4.4e-10 39.5 0.1 1.1e-09 38.2 0.1 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain K_channel_TID PF07941.11 EKX49288.1 - 0.091 13.2 4.1 0.2 12.1 4.1 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Cupin_8 PF13621.6 EKX49289.1 - 0.0001 22.1 0.0 0.00019 21.3 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain EF-hand_7 PF13499.6 EKX49292.1 - 5.8e-07 29.9 0.4 0.0034 17.8 0.0 2.7 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX49292.1 - 1.3e-05 24.7 3.8 0.34 10.9 0.0 3.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 EKX49292.1 - 1.7e-05 24.6 0.1 0.026 14.4 0.0 3.0 3 1 0 3 3 3 2 EF-hand domain pair MipZ PF09140.11 EKX49292.1 - 0.016 14.5 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 ATPase MipZ EF-hand_1 PF00036.32 EKX49292.1 - 0.044 13.3 1.6 20 5.0 0.0 3.9 4 0 0 4 4 4 0 EF hand TraB PF01963.17 EKX49292.1 - 0.049 13.5 1.7 0.25 11.2 0.3 2.0 2 0 0 2 2 2 0 TraB family Ion_trans_2 PF07885.16 EKX49293.1 - 1.6e-09 37.6 7.7 3.8e-09 36.4 7.7 1.5 1 0 0 1 1 1 1 Ion channel NPV_P10 PF05531.12 EKX49293.1 - 0.032 14.7 1.5 0.04 14.4 0.3 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF5534 PF17686.1 EKX49293.1 - 0.11 12.7 1.4 1.4 9.2 0.1 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5534) SK_channel PF03530.14 EKX49293.1 - 1.7 8.6 7.5 0.55 10.2 0.7 3.1 2 1 0 2 2 2 0 Calcium-activated SK potassium channel DUF1230 PF06799.11 EKX49293.1 - 2.4 8.3 6.7 0.83 9.8 0.8 2.9 2 1 0 3 3 3 0 Conserved in the green lineage and diatoms 27 Ion_trans PF00520.31 EKX49293.1 - 2.6 7.2 10.7 0.073 12.3 2.2 2.5 2 1 1 3 3 3 0 Ion transport protein MatE PF01554.18 EKX49295.1 - 9e-45 152.2 32.4 1.9e-22 79.6 11.4 2.2 2 0 0 2 2 2 2 MatE AbiEi_3_N PF17194.4 EKX49295.1 - 1.4 9.0 4.5 0.59 10.2 0.3 2.4 3 0 0 3 3 3 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain HMG_box PF00505.19 EKX49296.1 - 1.2e-16 60.9 1.3 1.2e-16 60.9 1.3 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EKX49296.1 - 1.5e-08 35.1 0.2 3.1e-08 34.1 0.2 1.5 1 0 0 1 1 1 1 HMG-box domain RBDV_coat PF06593.11 EKX49296.1 - 0.0019 17.7 0.1 0.0022 17.5 0.1 1.0 1 0 0 1 1 1 1 Raspberry bushy dwarf virus coat protein Elf1 PF05129.13 EKX49297.1 - 1.1e-25 89.4 7.3 1.4e-25 89.2 7.3 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like IBR PF01485.21 EKX49297.1 - 0.062 13.5 4.2 0.16 12.2 4.2 1.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Lar_restr_allev PF14354.6 EKX49297.1 - 0.088 13.2 5.9 0.2 12.1 5.9 1.9 1 1 0 1 1 1 0 Restriction alleviation protein Lar zinc_ribbon_4 PF13717.6 EKX49297.1 - 0.15 12.1 4.2 0.32 11.0 4.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Ribosomal_L37ae PF01780.19 EKX49297.1 - 0.39 10.8 5.6 0.81 9.8 5.6 1.6 1 1 0 1 1 1 0 Ribosomal L37ae protein family zf-AN1 PF01428.16 EKX49297.1 - 0.51 10.5 6.5 2.8 8.2 0.7 2.6 3 0 0 3 3 3 0 AN1-like Zinc finger Myosin_head PF00063.21 EKX49299.1 - 3e-132 442.2 0.0 9.8e-132 440.5 0.0 1.7 1 1 0 1 1 1 1 Myosin head (motor domain) Sigma54_activat PF00158.26 EKX49299.1 - 0.0089 15.7 0.1 1.2 8.8 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Hpr_kinase_C PF07475.12 EKX49299.1 - 0.013 15.1 0.1 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain DUF87 PF01935.17 EKX49299.1 - 0.02 15.0 0.1 0.041 14.0 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain TsaE PF02367.17 EKX49299.1 - 0.041 13.9 0.1 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EKX49299.1 - 0.073 13.3 0.0 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain TLD PF07534.16 EKX49300.1 - 2.1e-31 109.0 0.1 1.5e-15 57.6 0.0 2.3 2 0 0 2 2 2 2 TLD BTB_2 PF02214.22 EKX49300.1 - 1.9e-12 47.4 0.0 9.3e-05 22.7 0.0 2.7 2 1 0 2 2 2 2 BTB/POZ domain DUF3232 PF11554.8 EKX49300.1 - 0.06 13.7 0.3 0.13 12.6 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3232) TTL PF03133.15 EKX49301.1 - 2.1e-72 243.8 0.2 3.5e-48 164.2 0.1 2.7 1 1 1 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EKX49301.1 - 0.0017 17.7 0.0 1.1 8.4 0.0 2.7 2 1 0 2 2 2 2 YheC/D like ATP-grasp Profilin PF00235.19 EKX49302.1 - 7.4e-13 48.9 0.0 2.4e-12 47.2 0.0 1.7 1 1 0 1 1 1 1 Profilin SHE3 PF17078.5 EKX49303.1 - 0.0089 15.8 4.9 0.0089 15.8 4.9 4.1 4 0 0 4 4 4 2 SWI5-dependent HO expression protein 3 ECH_1 PF00378.20 EKX49304.1 - 4.3e-68 229.3 0.0 5.4e-68 229.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EKX49304.1 - 1.6e-16 60.7 0.0 2.1e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF1666 PF07891.12 EKX49304.1 - 0.087 12.5 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1666) SDH_sah PF01972.16 EKX49304.1 - 0.22 10.5 0.0 0.32 9.9 0.0 1.2 1 0 0 1 1 1 0 Serine dehydrogenase proteinase PDZ_6 PF17820.1 EKX49305.1 - 3.8e-21 74.7 1.1 6e-12 45.2 0.2 2.5 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 EKX49305.1 - 1.1e-19 70.5 3.9 2.1e-10 40.8 0.1 3.1 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 EKX49305.1 - 1.7e-19 69.9 0.7 1.1e-11 44.8 0.1 2.7 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 EKX49305.1 - 3.2e-11 43.0 0.7 0.00032 20.6 0.1 3.6 2 2 0 2 2 2 2 Tricorn protease PDZ domain Speriolin_N PF15058.6 EKX49305.1 - 0.001 19.2 1.2 0.0021 18.2 1.2 1.4 1 0 0 1 1 1 1 Speriolin N terminus Rootletin PF15035.6 EKX49305.1 - 0.0041 17.2 2.8 0.0041 17.2 2.8 2.2 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion ZapB PF06005.12 EKX49305.1 - 0.013 15.9 5.0 0.013 15.9 5.0 2.9 3 0 0 3 3 3 0 Cell division protein ZapB GRASP55_65 PF04495.14 EKX49305.1 - 0.033 14.5 0.0 8.4 6.7 0.0 2.7 2 1 1 3 3 3 0 GRASP55/65 PDZ-like domain YabA PF06156.13 EKX49305.1 - 0.037 14.7 2.1 0.037 14.7 2.1 2.5 2 0 0 2 2 2 0 Initiation control protein YabA HALZ PF02183.18 EKX49305.1 - 0.17 12.2 6.1 0.12 12.6 3.3 2.2 2 1 1 3 3 3 0 Homeobox associated leucine zipper DivIC PF04977.15 EKX49305.1 - 0.19 11.5 7.9 0.035 13.9 3.0 2.1 2 0 0 2 2 2 0 Septum formation initiator UPF0449 PF15136.6 EKX49305.1 - 1.4 9.4 6.8 0.55 10.7 1.8 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Fungal_TACC PF12709.7 EKX49305.1 - 1.9 9.0 11.1 1.3 9.6 4.9 2.5 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins bZIP_2 PF07716.15 EKX49305.1 - 3.1 7.9 11.5 0.21 11.7 5.8 2.0 2 0 0 2 2 2 0 Basic region leucine zipper GAS PF13851.6 EKX49305.1 - 4.4 6.6 13.0 0.096 12.0 1.8 2.6 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding PDZ_6 PF17820.1 EKX49306.1 - 5.4e-18 64.6 4.1 4.8e-09 35.9 0.1 2.3 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 EKX49306.1 - 1.1e-15 57.7 3.3 2.3e-08 34.3 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX49306.1 - 5.3e-12 45.9 1.1 3.9e-06 27.1 0.0 2.2 2 0 0 2 2 2 2 PDZ domain PDZ_4 PF17816.1 EKX49306.1 - 0.055 13.9 0.1 5 7.6 0.1 2.2 2 0 0 2 2 2 0 PDZ domain GRASP55_65 PF04495.14 EKX49306.1 - 0.065 13.6 0.1 0.18 12.2 0.1 1.8 1 1 0 1 1 1 0 GRASP55/65 PDZ-like domain Kinesin PF00225.23 EKX49307.1 - 1.1e-75 254.6 0.0 1.3e-75 254.4 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX49307.1 - 1.3e-12 47.8 0.0 2.8e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding FtsJ PF01728.19 EKX49309.1 - 8.3e-53 179.1 0.0 1e-52 178.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 EKX49309.1 - 0.043 14.5 0.0 0.41 11.4 0.0 2.5 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 EKX49309.1 - 0.047 13.5 0.0 1.5 8.6 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain zf-C3HC4_3 PF13920.6 EKX49310.1 - 2.5e-13 49.7 12.8 5e-13 48.7 12.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX49310.1 - 2.7e-06 27.6 15.4 8.1e-06 26.1 15.4 1.9 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EKX49310.1 - 1.3e-05 24.9 13.1 3.2e-05 23.7 13.1 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EKX49310.1 - 0.00068 19.4 17.0 0.0015 18.3 17.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX49310.1 - 0.22 11.5 14.7 0.56 10.2 14.7 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-P11 PF03854.14 EKX49310.1 - 0.72 9.6 9.4 1.8 8.3 9.4 1.6 1 0 0 1 1 1 0 P-11 zinc finger Ephrin_rec_like PF07699.13 EKX49311.1 - 2.2e-45 152.2 114.3 4.6e-08 32.7 0.6 12.0 2 2 11 13 13 13 13 Putative ephrin-receptor like NCD3G PF07562.14 EKX49311.1 - 7.1e-22 77.1 83.6 0.0075 16.2 1.3 12.0 2 2 9 13 13 13 12 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX49311.1 - 1.1e-09 38.5 86.5 0.13 12.7 1.8 14.7 2 2 10 14 14 14 9 TNFR/NGFR cysteine-rich region VSP PF03302.13 EKX49311.1 - 0.13 11.1 86.4 5.9 5.6 0.5 4.8 1 1 2 3 3 3 0 Giardia variant-specific surface protein JmjC PF02373.22 EKX49312.1 - 5.8e-17 62.2 0.0 1.2e-16 61.2 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 EKX49312.1 - 5.3e-07 29.5 0.0 1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 jmjN domain DBINO PF13892.6 EKX49313.1 - 0.73 10.2 6.8 0.21 12.0 0.8 2.2 2 0 0 2 2 2 0 DNA-binding domain DUF3287 PF11690.8 EKX49314.1 - 0.17 11.6 1.4 1.4 8.6 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) Flg_hook PF02120.16 EKX49314.1 - 0.17 11.8 0.0 0.41 10.6 0.0 1.6 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK Telomere_reg-2 PF10193.9 EKX49315.1 - 0.11 13.0 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Telomere length regulation protein Herpes_UL92 PF03048.14 EKX49316.1 - 1.2e-06 28.5 7.4 1.2e-06 28.5 7.4 2.0 2 1 1 3 3 3 1 UL92 family Sulfotransfer_4 PF17784.1 EKX49318.1 - 1.8e-30 106.4 0.3 1.9e-30 106.3 0.3 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EKX49318.1 - 0.001 19.5 0.0 0.0011 19.3 0.0 1.2 1 0 0 1 1 1 1 Sulfotransferase family Ephrin_rec_like PF07699.13 EKX49319.1 - 1.3e-56 188.1 97.6 3e-09 36.5 7.7 8.0 1 1 7 8 8 8 8 Putative ephrin-receptor like NCD3G PF07562.14 EKX49319.1 - 1.4e-19 69.8 66.4 0.0028 17.6 4.0 7.6 6 1 1 7 7 7 7 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX49319.1 - 1.7e-05 25.1 69.6 1.8 9.0 2.9 9.9 1 1 7 10 10 10 8 TNFR/NGFR cysteine-rich region VSP PF03302.13 EKX49319.1 - 2.5e-05 23.3 89.7 0.033 13.0 26.9 3.5 1 1 3 4 4 4 4 Giardia variant-specific surface protein P68HR PF08061.11 EKX49319.1 - 0.00094 19.3 11.9 81 3.5 0.1 6.5 6 0 0 6 6 6 0 P68HR (NUC004) repeat DUF4215 PF13948.6 EKX49319.1 - 7.7 7.0 49.7 2.2 8.8 5.5 5.8 2 1 5 7 7 7 0 Domain of unknown function (DUF4215) Ephrin_rec_like PF07699.13 EKX49320.1 - 5.4e-64 211.8 157.4 2.7e-09 36.7 9.4 9.3 1 1 9 10 10 10 10 Putative ephrin-receptor like NCD3G PF07562.14 EKX49320.1 - 5.7e-22 77.4 74.0 0.0031 17.4 3.7 8.4 5 1 3 9 9 9 9 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX49320.1 - 2.9e-06 27.6 79.2 0.55 10.7 0.9 11.1 1 1 10 12 12 12 10 TNFR/NGFR cysteine-rich region VSP PF03302.13 EKX49320.1 - 2.6e-05 23.3 104.7 0.027 13.3 26.4 4.1 1 1 3 4 4 4 4 Giardia variant-specific surface protein P68HR PF08061.11 EKX49320.1 - 0.00073 19.6 15.5 74 3.6 0.1 7.5 7 0 0 7 7 7 0 P68HR (NUC004) repeat zf-C2H2_11 PF16622.5 EKX49320.1 - 0.16 11.7 27.9 63 3.5 0.2 9.3 7 0 0 7 7 7 0 zinc-finger C2H2-type DUF4215 PF13948.6 EKX49320.1 - 0.23 11.9 52.7 1.6 9.2 5.0 6.3 2 2 5 7 7 7 0 Domain of unknown function (DUF4215) Shugoshin_N PF07558.11 EKX49321.1 - 0.0013 18.5 23.9 0.071 13.0 2.0 4.4 4 1 1 5 5 5 2 Shugoshin N-terminal coiled-coil region KASH_CCD PF14662.6 EKX49321.1 - 0.004 17.0 38.2 0.064 13.1 18.8 3.1 1 1 2 3 3 3 2 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 EKX49321.1 - 0.0045 17.1 24.1 0.74 10.0 5.5 4.0 2 1 2 4 4 4 3 bZIP transcription factor DivIC PF04977.15 EKX49321.1 - 0.012 15.4 26.8 0.093 12.5 2.4 4.5 3 1 2 5 5 5 0 Septum formation initiator Herpes_BLRF2 PF05812.12 EKX49321.1 - 0.015 15.4 19.1 0.93 9.6 0.3 3.3 1 1 2 3 3 3 0 Herpesvirus BLRF2 protein GIT_CC PF16559.5 EKX49321.1 - 0.11 12.4 15.2 0.057 13.3 2.5 3.7 2 1 2 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1192 PF06698.11 EKX49321.1 - 0.13 12.3 0.6 0.13 12.3 0.6 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) DUF2312 PF10073.9 EKX49321.1 - 0.17 11.6 10.1 1.1 9.0 0.5 3.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) ABC_tran_CTD PF16326.5 EKX49321.1 - 0.3 11.4 27.5 0.27 11.5 5.3 4.3 2 1 0 4 4 4 0 ABC transporter C-terminal domain DUF2935 PF11155.8 EKX49321.1 - 0.32 11.3 11.5 8.4 6.7 2.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Tropomyosin_1 PF12718.7 EKX49321.1 - 0.34 11.1 32.5 0.23 11.6 16.4 2.9 1 1 2 3 3 3 0 Tropomyosin like ADIP PF11559.8 EKX49321.1 - 0.83 9.7 32.5 0.51 10.4 13.2 3.0 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF1811 PF08838.10 EKX49321.1 - 1.1 9.5 20.4 1.2 9.4 0.9 3.8 3 2 0 3 3 3 0 Protein of unknown function (DUF1811) NPV_P10 PF05531.12 EKX49321.1 - 1.2 9.6 5.3 6.2 7.4 3.3 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein SLATT_6 PF18169.1 EKX49321.1 - 1.3 8.6 8.3 3.9 7.1 0.7 2.5 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 6 UPF0242 PF06785.11 EKX49321.1 - 1.3 9.0 29.7 1.3 9.1 9.5 2.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FlxA PF14282.6 EKX49321.1 - 1.5 8.9 26.5 1.2 9.2 7.2 3.1 2 1 1 3 3 3 0 FlxA-like protein Cluap1 PF10234.9 EKX49321.1 - 1.8 7.9 25.9 0.8 9.0 13.2 2.3 1 1 1 2 2 2 0 Clusterin-associated protein-1 Leu_zip PF15294.6 EKX49321.1 - 2 7.8 32.0 1 8.9 5.5 3.2 1 1 2 3 3 3 0 Leucine zipper ATG16 PF08614.11 EKX49321.1 - 2.4 8.3 34.4 2.2e+02 1.9 34.4 2.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 EKX49321.1 - 2.9 8.0 36.0 27 4.8 17.9 3.1 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Lipoprotein_20 PF13942.6 EKX49321.1 - 3.2 7.6 21.5 1.6 8.6 7.3 2.8 1 1 2 3 3 3 0 YfhG lipoprotein Baculo_PEP_C PF04513.12 EKX49321.1 - 3.5 7.7 12.1 0.7 9.9 6.8 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HALZ PF02183.18 EKX49321.1 - 3.9 7.8 14.2 5 7.4 0.5 3.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper CtIP_N PF10482.9 EKX49321.1 - 4.2 7.4 26.3 2.6 8.1 1.6 3.5 1 1 2 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain DASH_Dam1 PF08653.10 EKX49321.1 - 4.5 7.2 8.1 27 4.6 0.2 3.6 3 1 0 3 3 3 0 DASH complex subunit Dam1 APG6_N PF17675.1 EKX49321.1 - 4.9 7.7 36.0 0.87 10.1 17.5 3.0 1 1 2 3 3 3 0 Apg6 coiled-coil region DUF4988 PF16378.5 EKX49321.1 - 5.2 6.7 11.6 6.9 6.3 0.6 3.2 1 1 1 3 3 3 0 Domain of unknown function FapA PF03961.13 EKX49321.1 - 7 5.1 25.3 2.2 6.8 11.7 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A TSC22 PF01166.18 EKX49321.1 - 9.2 6.7 19.3 1.1 9.6 3.3 3.9 3 1 0 4 4 3 0 TSC-22/dip/bun family GTP_EFTU PF00009.27 EKX49322.1 - 1e-58 198.1 0.1 1.4e-58 197.7 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EKX49322.1 - 1.3e-29 102.7 0.0 2.8e-29 101.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EKX49322.1 - 1.7e-15 57.1 5.5 4.2e-15 55.9 5.5 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EKX49322.1 - 0.00012 22.2 0.0 0.00021 21.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 EKX49322.1 - 0.094 12.3 0.0 0.56 9.8 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Lsm_C PF14894.6 EKX49322.1 - 0.15 11.9 0.7 0.33 10.8 0.7 1.5 1 0 0 1 1 1 0 Lsm C-terminal Ephrin_rec_like PF07699.13 EKX49323.1 - 9.1e-15 54.2 37.5 6.2e-08 32.3 9.8 5.5 2 1 3 5 5 5 5 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX49323.1 - 2.4 8.6 23.8 0.81 10.1 1.6 4.8 3 1 2 5 5 5 0 TNFR/NGFR cysteine-rich region ShK PF01549.24 EKX49324.1 - 0.003 18.1 15.5 0.0052 17.3 15.5 1.4 1 0 0 1 1 1 1 ShK domain-like MORN PF02493.20 EKX49327.1 - 1.5e-16 59.2 17.0 3.3e-05 23.5 0.6 5.0 5 0 0 5 5 5 4 MORN repeat MORN PF02493.20 EKX49328.1 - 1.5e-15 56.0 18.1 0.00026 20.7 1.0 5.0 5 0 0 5 5 5 4 MORN repeat LRR_8 PF13855.6 EKX49329.1 - 3.1e-57 190.2 49.0 2.3e-14 52.9 3.2 7.0 2 2 8 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 EKX49329.1 - 1.7e-24 85.5 24.0 2.9e-06 27.5 0.8 7.9 3 2 7 10 10 10 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX49329.1 - 7.6e-22 77.6 2.6 9.5e-09 35.3 0.0 3.1 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 EKX49329.1 - 1.3e-12 47.6 2.5 0.00061 19.3 0.1 3.7 1 1 2 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 EKX49329.1 - 2.4e-08 33.4 19.0 5 8.1 0.0 9.5 10 1 0 10 10 10 3 Leucine Rich Repeat LRR_6 PF13516.6 EKX49329.1 - 0.00017 21.4 11.3 6.1 7.2 0.0 7.5 8 0 0 8 8 8 1 Leucine Rich repeat DUF1231 PF06802.11 EKX49329.1 - 0.015 14.5 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1231) DUF4924 PF16271.5 EKX49329.1 - 0.037 14.1 0.1 0.15 12.1 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4924) Alpha_kinase PF02816.18 EKX49331.1 - 2.6e-55 187.4 0.0 3.3e-55 187.1 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family BTB PF00651.31 EKX49332.1 - 7.2e-07 29.4 0.0 0.014 15.6 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain BACK PF07707.15 EKX49332.1 - 7.3e-05 22.8 1.5 0.0052 16.9 1.0 3.2 2 1 0 2 2 2 1 BTB And C-terminal Kelch Spt5_N PF11942.8 EKX49332.1 - 0.053 14.5 0.1 0.053 14.5 0.1 3.3 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal DUF4281 PF14108.6 EKX49333.1 - 4.4e-34 117.6 7.0 5.9e-34 117.2 7.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) DPM3 PF08285.11 EKX49333.1 - 0.67 10.2 3.2 1 9.6 1.0 2.0 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Pkinase PF00069.25 EKX49334.1 - 4e-45 154.2 0.0 3.2e-44 151.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX49334.1 - 1.4e-29 103.2 0.0 4.2e-15 55.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EKX49334.1 - 0.00062 19.2 0.0 0.018 14.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DUF5320 PF17253.2 EKX49335.1 - 0.094 13.8 0.5 0.16 13.0 0.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5320) FemAB_like PF04339.12 EKX49337.1 - 0.072 12.2 0.3 0.081 12.0 0.3 1.0 1 0 0 1 1 1 0 Peptidogalycan biosysnthesis/recognition Tox-SHH PF15652.6 EKX49337.1 - 0.12 13.4 1.4 0.2 12.6 1.4 1.5 1 1 0 1 1 1 0 HNH/Endo VII superfamily toxin with a SHH signature DUF2229 PF09989.9 EKX49337.1 - 0.17 11.5 0.6 0.21 11.2 0.6 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) PALP PF00291.25 EKX49338.1 - 5.7e-43 147.4 0.0 6.6e-42 143.9 0.0 2.2 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PTS_EIIC_2 PF13303.6 EKX49338.1 - 0.012 14.7 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase system, EIIC DnaJ PF00226.31 EKX49340.1 - 9.5e-27 92.9 0.8 1e-26 92.8 0.8 1.0 1 0 0 1 1 1 1 DnaJ domain Glyco_tran_WbsX PF14307.6 EKX49341.1 - 4.9e-14 52.5 0.8 1e-10 41.6 0.0 2.8 2 1 0 2 2 2 2 Glycosyltransferase WbsX Glyco_hydro_99 PF16317.5 EKX49341.1 - 4.7e-06 26.0 9.6 0.00025 20.3 0.9 3.8 2 2 1 3 3 3 2 Glycosyl hydrolase family 99 DUF4214 PF13946.6 EKX49341.1 - 0.014 15.4 0.4 0.039 14.0 0.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4214) Hist_deacetyl PF00850.19 EKX49342.1 - 2.1e-57 194.9 0.0 2.6e-57 194.6 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain ABC_membrane PF00664.23 EKX49343.1 - 1.9e-58 198.3 2.7 2.5e-58 197.9 2.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EKX49343.1 - 7e-33 114.1 0.0 2.7e-32 112.2 0.0 1.9 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EKX49343.1 - 3e-09 36.6 0.1 8.3e-07 28.7 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EKX49343.1 - 0.00094 18.9 0.1 0.11 12.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EKX49343.1 - 0.0012 19.2 0.3 0.017 15.5 0.3 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EKX49343.1 - 0.0097 16.2 0.0 0.033 14.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EKX49343.1 - 0.011 15.4 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EKX49343.1 - 0.024 14.5 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ABC_membrane_2 PF06472.15 EKX49343.1 - 0.026 14.0 4.9 0.0098 15.3 2.1 1.7 2 0 0 2 2 2 0 ABC transporter transmembrane region 2 SbcCD_C PF13558.6 EKX49343.1 - 0.041 14.1 0.8 0.63 10.3 0.8 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DsbB PF02600.16 EKX49343.1 - 0.042 14.3 0.0 0.99 9.8 0.0 2.4 2 0 0 2 2 2 0 Disulfide bond formation protein DsbB Zeta_toxin PF06414.12 EKX49343.1 - 0.13 11.5 0.0 0.36 10.1 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Pkinase_Tyr PF07714.17 EKX49344.1 - 2.1e-50 171.4 0.0 2.7e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX49344.1 - 1.7e-33 116.1 0.0 2.3e-33 115.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EKX49344.1 - 2.1e-05 24.2 0.1 5.1e-05 23.0 0.1 1.6 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 EKX49344.1 - 0.00012 21.5 0.4 0.00019 20.9 0.4 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX49344.1 - 0.013 15.4 0.1 0.05 13.5 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX49344.1 - 0.021 13.6 0.0 0.028 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PDZ_6 PF17820.1 EKX49345.1 - 0.095 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 PDZ domain zf-4CXXC_R1 PF10497.9 EKX49348.1 - 0.00013 22.2 19.5 0.00027 21.1 19.5 1.6 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Hist_deacetyl PF00850.19 EKX49349.1 - 6.5e-71 239.3 0.0 1.4e-70 238.3 0.0 1.4 2 0 0 2 2 2 1 Histone deacetylase domain DnaJ PF00226.31 EKX49351.1 - 1.4e-15 57.2 0.0 1.5e-15 57.0 0.0 1.0 1 0 0 1 1 1 1 DnaJ domain COMM_domain PF07258.14 EKX49351.1 - 0.16 12.1 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 COMM domain Fez1 PF06818.15 EKX49352.1 - 0.001 19.6 19.5 0.001 19.6 19.5 4.9 2 1 2 4 4 4 2 Fez1 Filament PF00038.21 EKX49352.1 - 0.0025 17.4 11.5 0.0025 17.4 11.5 5.7 2 2 1 3 3 3 2 Intermediate filament protein Cob_adeno_trans PF01923.18 EKX49352.1 - 0.012 15.8 2.4 0.012 15.8 2.4 4.5 2 1 2 4 4 4 0 Cobalamin adenosyltransferase HALZ PF02183.18 EKX49352.1 - 0.039 14.2 0.1 0.039 14.2 0.1 8.2 10 0 0 10 10 10 0 Homeobox associated leucine zipper Tropomyosin_1 PF12718.7 EKX49352.1 - 0.052 13.7 0.4 0.052 13.7 0.4 6.7 5 3 1 6 6 5 0 Tropomyosin like DUF1192 PF06698.11 EKX49352.1 - 1.3 9.1 18.8 9.5 6.4 0.4 6.8 6 1 1 7 7 7 0 Protein of unknown function (DUF1192) WXG100 PF06013.12 EKX49352.1 - 1.4 9.2 21.5 0.12 12.6 1.8 5.6 6 1 0 6 6 6 0 Proteins of 100 residues with WXG FlaC_arch PF05377.11 EKX49352.1 - 2.9 8.3 38.4 8.6 6.8 0.6 8.3 6 2 2 8 8 7 0 Flagella accessory protein C (FlaC) ATG16 PF08614.11 EKX49352.1 - 3.5 7.8 82.1 1 9.6 6.2 6.3 2 2 3 5 5 5 0 Autophagy protein 16 (ATG16) SAC3 PF12209.8 EKX49352.1 - 3.5 7.9 7.6 0.31 11.2 0.6 3.0 3 0 0 3 3 3 0 Leucine permease transcriptional regulator helical domain DUF3450 PF11932.8 EKX49352.1 - 4.1 6.6 52.0 0.031 13.6 6.6 5.8 3 3 2 5 5 5 0 Protein of unknown function (DUF3450) NPV_P10 PF05531.12 EKX49352.1 - 4.6 7.8 14.7 12 6.5 0.4 5.6 4 2 1 5 5 5 0 Nucleopolyhedrovirus P10 protein LPP PF04728.13 EKX49352.1 - 5.3 7.5 22.3 41 4.7 0.0 7.7 5 3 2 7 7 7 0 Lipoprotein leucine-zipper Baculo_PEP_C PF04513.12 EKX49352.1 - 5.5 7.0 18.7 7.5 6.6 0.5 4.5 3 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2353 PF09789.9 EKX49352.1 - 6.2 6.1 61.9 0.63 9.3 11.7 5.4 1 1 2 5 5 5 0 Uncharacterized coiled-coil protein (DUF2353) Imm-NTF2 PF15655.6 EKX49353.1 - 0.059 13.7 1.6 0.59 10.4 0.2 2.7 2 0 0 2 2 2 0 NTF2 fold immunity protein RbsD_FucU PF05025.13 EKX49353.1 - 0.12 12.8 2.4 0.34 11.3 2.4 1.7 1 0 0 1 1 1 0 RbsD / FucU transport protein family Laminin_B PF00052.18 EKX49353.1 - 0.28 11.1 4.1 0.84 9.5 0.7 3.2 3 0 0 3 3 3 0 Laminin B (Domain IV) Med2 PF11214.8 EKX49353.1 - 0.45 10.7 6.0 0.097 12.8 1.2 2.5 2 0 0 2 2 2 0 Mediator complex subunit 2 PIN_8 PF18476.1 EKX49353.1 - 2 8.2 10.3 0.34 10.7 4.7 2.4 1 1 1 2 2 2 0 PIN like domain MCM_OB PF17207.3 EKX49353.1 - 6.8 6.6 6.0 0.93 9.3 0.4 2.2 2 0 0 2 2 2 0 MCM OB domain CAAD PF14159.6 EKX49355.1 - 0.22 11.4 0.2 0.22 11.4 0.2 1.5 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Q_salvage PF10343.9 EKX49356.1 - 1.5e-78 264.3 0.0 1.9e-78 263.9 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DUF1688 PF07958.11 EKX49356.1 - 0.017 13.8 0.2 0.21 10.3 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1688) Bac_rhodopsin PF01036.18 EKX49358.1 - 7.6e-41 140.1 23.8 9.2e-41 139.9 23.8 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF21 PF01595.20 EKX49358.1 - 0.75 9.5 8.2 0.091 12.5 3.6 1.8 2 1 0 2 2 2 0 Cyclin M transmembrane N-terminal domain OST3_OST6 PF04756.13 EKX49358.1 - 5.7 6.2 10.4 15 4.8 10.4 1.7 1 1 0 1 1 1 0 OST3 / OST6 family, transporter family PT-VENN PF04829.13 EKX49359.1 - 0.37 10.9 3.5 0.38 10.9 0.3 2.3 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif zf-CCHC_3 PF13917.6 EKX49360.1 - 2.7e-06 27.2 0.2 2.7e-06 27.2 0.2 2.0 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 EKX49360.1 - 7.5e-05 22.6 1.4 0.00014 21.8 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle Paramyxo_ncap PF00973.19 EKX49360.1 - 0.019 13.9 14.9 0.024 13.6 14.9 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein RR_TM4-6 PF06459.12 EKX49360.1 - 3.3 7.5 21.2 4.8 6.9 21.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.7 EKX49360.1 - 8.1 4.4 15.7 8.1 4.4 15.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TOM20_plant PF06552.12 EKX49361.1 - 2.4e-17 63.3 10.4 7.7e-13 48.6 1.2 2.1 1 1 1 2 2 2 2 Plant specific mitochondrial import receptor subunit TOM20 DUF627 PF04781.12 EKX49361.1 - 0.0061 16.6 3.2 0.67 10.0 0.1 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF627) Metallophos PF00149.28 EKX49362.1 - 8.6e-39 134.1 0.1 1.1e-38 133.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EKX49362.1 - 1.1e-23 83.4 0.4 3.5e-23 81.8 0.2 1.9 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain FAM35_C PF15793.5 EKX49362.1 - 0.56 9.6 2.1 1 8.8 2.1 1.3 1 0 0 1 1 1 0 Protein family FAM35, C-terminal PDZ_6 PF17820.1 EKX49364.1 - 5.3e-09 35.8 0.1 1.7e-08 34.2 0.0 1.7 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX49364.1 - 3.6e-08 33.7 0.1 9.8e-08 32.2 0.0 1.6 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX49364.1 - 8e-06 26.1 0.0 1.2e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 PDZ domain FAM183 PF14886.6 EKX49365.1 - 1.1e-05 26.1 0.0 1.5e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 FAM183A and FAM183B related GBP PF02263.19 EKX49366.1 - 1e-66 224.9 1.7 1.7e-66 224.2 0.0 2.2 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 EKX49366.1 - 1.1e-25 90.7 29.8 1.1e-25 90.7 29.8 2.6 1 1 1 2 2 2 1 Guanylate-binding protein, C-terminal domain MMR_HSR1 PF01926.23 EKX49366.1 - 0.064 13.4 0.0 0.32 11.1 0.0 2.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase SNARE_assoc PF09335.11 EKX49367.1 - 7.7e-14 52.2 5.6 7.7e-14 52.2 5.6 1.9 3 0 0 3 3 3 1 SNARE associated Golgi protein PP2C PF00481.21 EKX49368.1 - 1.7e-52 178.6 0.1 2e-52 178.4 0.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EKX49368.1 - 0.0015 18.3 0.1 0.0025 17.5 0.1 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C Foie-gras_1 PF11817.8 EKX49369.1 - 1.5e-19 70.6 4.6 3.2e-19 69.5 4.6 1.6 1 0 0 1 1 1 1 Foie gras liver health family 1 Pkinase PF00069.25 EKX49370.1 - 1.5e-54 185.1 0.0 3e-51 174.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EKX49370.1 - 1.3e-31 109.9 0.0 2e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX49370.1 - 1.2e-10 41.2 0.0 2.6e-10 40.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EKX49370.1 - 5.2e-06 26.0 0.0 9.9e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EKX49370.1 - 5.3e-06 25.5 0.1 8.9e-06 24.7 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX49370.1 - 8.8e-05 22.5 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EKX49370.1 - 0.16 11.5 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RVT_1 PF00078.27 EKX49371.1 - 4.9e-08 32.8 0.0 2.4e-05 23.9 0.0 2.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ORC5_C PF14630.6 EKX49371.1 - 0.047 13.2 0.1 0.047 13.2 0.1 2.4 3 0 0 3 3 3 0 Origin recognition complex (ORC) subunit 5 C-terminus Methyltransf_16 PF10294.9 EKX49372.1 - 3.8e-09 36.5 0.1 9.7e-09 35.2 0.1 1.6 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 EKX49372.1 - 8.4e-05 23.2 0.2 0.00033 21.3 0.1 1.8 1 1 1 2 2 2 1 Methyltransferase domain TehB PF03848.14 EKX49372.1 - 0.0005 19.5 0.0 0.00075 19.0 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.14 EKX49372.1 - 0.0011 18.6 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EKX49372.1 - 0.0013 19.3 0.1 0.0025 18.4 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain DUF2252 PF10009.9 EKX49372.1 - 0.011 14.8 0.1 0.015 14.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Methyltransf_31 PF13847.6 EKX49372.1 - 0.013 15.3 0.1 0.022 14.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EKX49372.1 - 0.078 12.3 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) HU-CCDC81_euk_2 PF18289.1 EKX49373.1 - 4.6e-05 23.5 0.0 9.8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 LURAP PF14854.6 EKX49373.1 - 0.044 13.7 0.8 0.12 12.3 0.8 1.7 1 0 0 1 1 1 0 Leucine rich adaptor protein DUF1682 PF07946.14 EKX49373.1 - 0.61 9.2 0.0 0.61 9.2 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1682) HTH_AsnC-type PF13404.6 EKX49374.1 - 0.026 14.3 0.1 12 5.8 0.0 2.7 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain Activator-TraM PF11657.8 EKX49374.1 - 0.06 13.2 0.0 9.7 6.0 0.0 2.2 1 1 1 2 2 2 0 Transcriptional activator TraM MCR PF18509.1 EKX49374.1 - 1.9 8.1 9.3 9.3 5.9 0.4 3.2 3 0 0 3 3 3 0 Magnetochrome domain PEGSRP PF07623.11 EKX49374.1 - 9.3 6.2 12.2 46 4.0 0.5 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1584) His_biosynth PF00977.21 EKX49376.1 - 3.2e-30 105.3 0.0 4e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Aldolase PF01081.19 EKX49376.1 - 0.019 14.4 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 KDPG and KHG aldolase Ribul_P_3_epim PF00834.19 EKX49376.1 - 0.035 13.5 0.0 0.07 12.5 0.0 1.5 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family zf-AD PF07776.15 EKX49377.1 - 0.056 13.7 2.1 0.21 11.9 2.1 2.1 1 1 0 1 1 1 0 Zinc-finger associated domain (zf-AD) DGF-1_C PF11040.8 EKX49377.1 - 0.18 11.8 0.6 2.5 8.2 0.1 2.5 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus 4HB PF17947.1 EKX49377.1 - 0.21 11.7 0.7 0.9 9.6 0.0 2.3 3 0 0 3 3 3 0 Four helical bundle domain Mucin-like PF16058.5 EKX49378.1 - 0.0065 16.5 6.6 1.7 8.8 0.5 3.3 1 1 3 4 4 4 4 Mucin-like CTP_transf_like PF01467.26 EKX49379.1 - 3.5e-24 85.6 0.0 4.7e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like Pribosyltran PF00156.27 EKX49380.1 - 2.8e-19 69.2 0.1 3.8e-19 68.7 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PDZ_6 PF17820.1 EKX49381.1 - 7.8e-08 32.1 0.1 2.1e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX49381.1 - 0.00061 20.1 0.3 0.0021 18.3 0.0 2.1 2 1 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX49381.1 - 0.00094 19.5 0.2 0.002 18.4 0.2 1.5 1 0 0 1 1 1 1 PDZ domain Pkinase_Tyr PF07714.17 EKX49382.1 - 4.9e-37 127.6 0.0 5.3e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX49382.1 - 3.2e-36 125.1 0.0 3.7e-36 124.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EKX49382.1 - 0.0064 15.9 0.2 0.0091 15.4 0.2 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EKX49382.1 - 0.052 12.9 0.0 0.062 12.6 0.0 1.1 1 0 0 1 1 1 0 Kinase-like AAR2 PF05282.11 EKX49384.1 - 2.5e-36 125.9 0.3 3e-34 119.0 0.2 2.1 1 1 1 2 2 2 2 AAR2 protein PUL PF08324.11 EKX49386.1 - 8e-13 48.2 0.8 8.9e-13 48.1 0.8 1.1 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 EKX49387.1 - 4.4e-41 140.2 0.0 6.2e-41 139.7 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 EKX49387.1 - 0.14 12.5 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase adh_short PF00106.25 EKX49388.1 - 7.7e-13 48.3 0.0 2.3e-09 37.0 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EKX49388.1 - 1.2e-06 28.3 0.0 4.4e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX49388.1 - 9.8e-05 22.3 0.0 0.00022 21.2 0.0 1.5 1 0 0 1 1 1 1 KR domain Ribonuc_L-PSP PF01042.21 EKX49388.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Endoribonuclease L-PSP WW PF00397.26 EKX49389.1 - 8.6e-10 38.5 2.0 1.7e-09 37.6 2.0 1.5 1 0 0 1 1 1 1 WW domain RPW8 PF05659.11 EKX49389.1 - 0.0025 17.5 0.4 0.0047 16.6 0.4 1.4 1 0 0 1 1 1 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 Spc7 PF08317.11 EKX49389.1 - 0.058 12.3 2.8 0.13 11.1 2.8 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein UMP1 PF05348.11 EKX49389.1 - 0.075 13.3 1.2 5 7.4 0.0 2.6 2 0 0 2 2 2 0 Proteasome maturation factor UMP1 RRM_1 PF00076.22 EKX49390.1 - 5.7e-28 96.5 0.0 4.9e-15 55.1 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EKX49390.1 - 1e-07 31.8 0.3 4.8e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EKX49390.1 - 0.00033 20.7 0.2 1.2 9.3 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif DUF4651 PF15513.6 EKX49390.1 - 0.016 15.0 0.0 0.47 10.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) GTP_EFTU_D3 PF03143.17 EKX49390.1 - 0.042 14.2 0.0 0.071 13.4 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu C-terminal domain RRM_3 PF08777.11 EKX49390.1 - 0.097 12.7 0.0 0.72 9.9 0.0 2.1 2 1 0 2 2 2 0 RNA binding motif PHM7_cyt PF14703.6 EKX49390.1 - 0.2 11.9 0.2 2.6 8.3 0.1 2.5 2 2 2 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter Abhydrolase_1 PF00561.20 EKX49391.1 - 8e-19 68.3 0.0 3.3e-17 63.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EKX49391.1 - 1e-10 42.6 3.3 1.5e-10 42.1 3.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EKX49391.1 - 1.2e-08 34.6 0.0 3e-05 23.4 0.0 2.5 2 1 0 2 2 2 2 Serine aminopeptidase, S33 NPV_P10 PF05531.12 EKX49392.1 - 8.1 7.0 11.7 11 6.6 0.4 4.9 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein TMF_TATA_bd PF12325.8 EKX49393.1 - 0.00045 20.4 13.1 0.00045 20.4 13.1 6.0 2 2 4 6 6 6 2 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 EKX49393.1 - 0.0005 19.1 15.5 0.0005 19.1 15.5 5.0 1 1 3 5 5 5 2 Spc7 kinetochore protein P22_Tail-4 PF11650.8 EKX49393.1 - 0.0038 17.2 0.3 0.012 15.6 0.3 1.8 1 0 0 1 1 1 1 P22 tail accessory factor DUF4407 PF14362.6 EKX49393.1 - 2.3 7.5 45.1 0.35 10.2 11.2 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Vpu PF00558.19 EKX49394.1 - 0.0025 17.6 3.4 0.36 10.6 0.1 2.2 2 0 0 2 2 2 2 Vpu protein Collagen PF01391.18 EKX49394.1 - 0.0041 16.8 11.0 0.012 15.4 4.2 2.1 2 0 0 2 2 2 2 Collagen triple helix repeat (20 copies) Cytomega_TRL10 PF06084.11 EKX49394.1 - 0.11 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein zf-C4H2 PF10146.9 EKX49394.1 - 0.2 11.9 8.3 0.21 11.9 3.0 2.1 2 0 0 2 2 2 0 Zinc finger-containing protein zf-H2C2_2 PF13465.6 EKX49395.1 - 1.6e-50 167.4 48.3 1.4e-10 41.1 0.1 8.2 8 0 0 8 8 8 7 Zinc-finger double domain zf-C2H2 PF00096.26 EKX49395.1 - 6.7e-38 127.1 65.1 6.3e-07 29.5 0.4 8.1 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EKX49395.1 - 7.2e-28 94.9 59.2 3.8e-05 24.2 0.5 8.1 8 0 0 8 8 8 8 C2H2-type zinc finger zf-met PF12874.7 EKX49395.1 - 6.6e-21 74.0 50.6 6.2e-05 23.3 0.5 8.2 8 0 0 8 8 8 7 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EKX49395.1 - 3.7e-18 65.3 38.4 0.0017 18.6 0.2 7.9 8 0 0 8 8 8 7 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EKX49395.1 - 6.8e-07 29.1 61.4 0.0021 18.0 0.6 8.8 8 2 0 8 8 8 4 C2H2-type zinc finger zf_UBZ PF18439.1 EKX49395.1 - 0.00065 19.2 33.7 1.6 8.4 0.1 8.0 8 0 0 8 8 8 2 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 EKX49395.1 - 0.00067 19.7 29.9 3.2 7.9 2.8 6.5 5 3 1 6 6 6 4 Zinc ribbon domain C1_2 PF03107.16 EKX49395.1 - 0.0012 19.1 43.3 4.1 7.8 7.7 7.6 1 1 5 6 6 6 1 C1 domain zf-Di19 PF05605.12 EKX49395.1 - 0.0046 17.2 34.8 0.046 14.0 3.1 4.9 1 1 4 6 6 6 4 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 EKX49395.1 - 0.0099 15.6 0.2 0.0099 15.6 0.2 7.9 8 2 0 8 8 7 3 C2H2-type zinc-finger domain Zf_RING PF16744.5 EKX49395.1 - 0.011 15.9 29.4 0.24 11.5 0.1 7.3 1 1 7 8 8 8 0 KIAA1045 RING finger DUF3268 PF11672.8 EKX49395.1 - 0.012 15.9 18.3 1.4 9.3 0.5 3.9 4 1 0 4 4 3 0 zinc-finger-containing domain zinc_ribbon_15 PF17032.5 EKX49395.1 - 0.015 16.0 26.2 0.49 11.2 0.9 4.7 1 1 3 5 5 5 0 zinc-ribbon family zf-FCS PF06467.14 EKX49395.1 - 0.018 14.9 29.5 4.6 7.3 0.3 6.9 6 1 1 7 7 7 0 MYM-type Zinc finger with FCS sequence motif HypA PF01155.19 EKX49395.1 - 0.034 14.2 23.5 0.12 12.4 1.8 5.0 1 1 2 3 3 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA BolA PF01722.18 EKX49395.1 - 0.087 13.1 7.4 1.9 8.8 0.9 4.0 2 2 1 3 3 3 0 BolA-like protein Orn_DAP_Arg_deC PF00278.22 EKX49395.1 - 0.12 12.6 0.2 0.57 10.4 0.1 2.2 1 1 1 2 2 2 0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Cript PF10235.9 EKX49395.1 - 0.15 12.7 29.4 0.79 10.3 2.0 6.0 3 2 3 6 6 6 0 Microtubule-associated protein CRIPT Elf1 PF05129.13 EKX49395.1 - 0.2 11.7 29.3 0.29 11.2 3.4 5.5 1 1 5 6 6 6 0 Transcription elongation factor Elf1 like zf-C2HC_2 PF13913.6 EKX49395.1 - 0.21 11.6 34.7 0.68 9.9 0.0 6.9 7 0 0 7 7 6 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 EKX49395.1 - 0.23 11.3 37.0 0.19 11.5 0.4 7.3 8 0 0 8 8 7 0 zinc-finger C2H2-type DUF2180 PF09947.9 EKX49395.1 - 0.23 11.5 17.8 3.9 7.5 0.0 4.7 2 2 3 5 5 5 0 Uncharacterized protein conserved in archaea (DUF2180) zf-C2H2_2 PF12756.7 EKX49395.1 - 0.64 10.4 41.9 1.7 9.1 0.3 7.1 1 1 5 6 6 5 0 C2H2 type zinc-finger (2 copies) zf-Sec23_Sec24 PF04810.15 EKX49395.1 - 0.65 10.1 25.2 1 9.5 0.1 6.8 5 3 2 7 7 7 0 Sec23/Sec24 zinc finger zinc_ribbon_9 PF14369.6 EKX49395.1 - 0.75 10.1 19.8 1.1 9.6 0.1 6.0 7 0 0 7 7 7 0 zinc-ribbon Baculo_IE-1 PF05290.11 EKX49395.1 - 0.77 9.7 15.5 16 5.4 0.1 4.9 2 1 1 3 3 3 0 Baculovirus immediate-early protein (IE-0) zf-C2HE PF16278.5 EKX49395.1 - 1.1 9.7 46.3 1.5 9.4 0.7 7.4 2 1 5 7 7 7 0 C2HE / C2H2 / C2HC zinc-binding finger XPA_N PF01286.18 EKX49395.1 - 1.6 8.9 34.4 5.4 7.2 0.2 7.8 8 0 0 8 8 8 0 XPA protein N-terminal zf-ribbon_3 PF13248.6 EKX49395.1 - 2.4 7.7 24.5 2.1 7.9 0.0 6.7 8 0 0 8 8 8 0 zinc-ribbon domain FYVE PF01363.21 EKX49395.1 - 2.4 8.4 42.4 8.7 6.6 3.0 5.7 1 1 2 3 3 3 0 FYVE zinc finger TPR_1 PF00515.28 EKX49396.1 - 1.4e-10 40.5 0.1 5.5e-07 29.1 0.1 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX49396.1 - 4.1e-09 35.9 0.1 2.9e-05 23.8 0.1 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX49396.1 - 3.1e-07 30.1 0.1 0.00011 22.1 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX49396.1 - 0.00012 22.6 0.1 0.0075 17.0 0.0 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX49396.1 - 0.0017 18.3 0.5 0.16 12.1 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX49396.1 - 0.0024 17.5 0.0 0.1 12.3 0.1 2.1 1 1 1 2 2 2 1 TPR repeat TPR_17 PF13431.6 EKX49396.1 - 0.0047 17.2 0.1 1 9.9 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX49396.1 - 0.088 13.5 0.1 0.12 13.0 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat zf_CCCH_4 PF18345.1 EKX49396.1 - 0.088 12.9 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Zinc finger domain TPR_12 PF13424.6 EKX49396.1 - 0.09 13.1 0.3 0.36 11.1 0.3 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 EKX49396.1 - 0.091 12.9 0.2 0.12 12.5 0.2 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat NARP1 PF12569.8 EKX49396.1 - 0.17 10.8 0.0 0.2 10.5 0.0 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF3136 PF11334.8 EKX49398.1 - 0.62 9.9 7.1 11 5.9 0.1 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF3136) TIG PF01833.24 EKX49401.1 - 2.1e-41 139.9 41.1 7.8e-13 48.3 0.1 13.5 12 0 0 12 12 12 5 IPT/TIG domain EPTP PF03736.17 EKX49401.1 - 7e-14 51.5 8.9 0.017 15.1 0.0 8.4 9 0 0 9 9 9 4 EPTP domain Laminin_G_3 PF13385.6 EKX49401.1 - 1.6e-13 51.1 0.4 1.6e-13 51.1 0.4 2.5 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Anth_Ig PF05587.13 EKX49401.1 - 3.6e-06 27.2 2.1 2.6 8.4 0.0 6.2 5 0 0 5 5 5 2 Anthrax receptor extracellular domain CUB PF00431.20 EKX49401.1 - 8.4e-05 22.9 0.0 0.00031 21.1 0.0 2.0 2 0 0 2 2 2 1 CUB domain TIG_plexin PF17960.1 EKX49401.1 - 0.00014 21.8 0.7 13 5.9 0.0 6.2 6 0 0 6 6 6 1 TIG domain Big_9 PF17963.1 EKX49401.1 - 0.00024 21.8 23.2 2.6 8.9 0.1 12.0 13 0 0 13 13 13 2 Bacterial Ig domain TIG_2 PF18020.1 EKX49401.1 - 0.027 15.1 2.1 4.1 8.1 0.0 4.8 6 0 0 6 6 6 0 TIG domain found in plexin Lactonase PF10282.9 EKX49401.1 - 0.085 12.1 0.0 0.23 10.7 0.0 1.7 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Fibrinogen_C PF00147.18 EKX49401.1 - 0.15 11.8 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Fibrinogen beta and gamma chains, C-terminal globular domain Gp-FAR-1 PF05823.12 EKX49402.1 - 1.7 9.0 6.6 0.24 11.7 1.0 2.0 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Sas10_Utp3 PF04000.15 EKX49403.1 - 5.8e-14 52.5 0.1 1.1e-13 51.6 0.1 1.4 1 0 0 1 1 1 1 Sas10/Utp3/C1D family CdvA PF18822.1 EKX49403.1 - 0.0092 15.8 2.0 0.024 14.5 2.0 1.7 1 1 0 1 1 1 1 CdvA-like coiled-coil domain CLZ PF16526.5 EKX49403.1 - 0.012 15.9 3.0 0.2 12.1 0.0 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3450 PF11932.8 EKX49403.1 - 0.03 13.6 1.7 0.14 11.5 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF1732 PF08340.11 EKX49403.1 - 0.062 13.3 0.3 0.17 11.9 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1732) UPF0184 PF03670.13 EKX49403.1 - 0.095 13.1 2.7 0.92 9.9 0.5 2.5 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) TPR_1 PF00515.28 EKX49404.1 - 6.2e-08 32.1 1.4 0.096 12.6 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX49404.1 - 7.1e-07 29.0 3.5 0.0084 16.3 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX49404.1 - 8.3e-07 29.2 1.7 3.1e-05 24.2 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX49404.1 - 7.2e-06 25.7 1.9 0.042 13.7 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX49404.1 - 0.0025 17.8 1.4 4.3 7.7 0.3 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat EMP70 PF02990.16 EKX49406.1 - 8.9e-152 506.4 24.6 1.1e-151 506.0 24.6 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 PI3_PI4_kinase PF00454.27 EKX49407.1 - 7.6e-14 52.1 0.0 9e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase NLRC4_HD2 PF17776.1 EKX49407.1 - 0.09 13.3 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 NLRC4 helical domain HD2 Thioredoxin PF00085.20 EKX49409.1 - 7.6e-37 125.4 1.0 1.9e-18 66.3 0.2 2.1 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_7 PF13899.6 EKX49409.1 - 8.1e-09 35.6 0.2 0.00025 21.1 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EKX49409.1 - 1.5e-08 35.0 1.1 0.005 17.3 0.2 2.3 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EKX49409.1 - 3.1e-05 24.2 0.1 0.13 12.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Glutaredoxin PF00462.24 EKX49409.1 - 0.0001 22.4 0.7 0.057 13.6 0.1 2.5 2 0 0 2 2 2 2 Glutaredoxin AhpC-TSA PF00578.21 EKX49409.1 - 0.00012 22.0 0.3 0.082 12.8 0.0 2.2 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_3 PF13192.6 EKX49409.1 - 0.1 12.7 0.5 2.2 8.4 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin domain Sporozoite_P67 PF05642.11 EKX49409.1 - 1.1 7.2 2.8 1.3 7.1 2.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Keratin_2_head PF16208.5 EKX49409.1 - 2 8.5 21.8 3.1 7.9 21.8 1.2 1 0 0 1 1 1 0 Keratin type II head Hira PF07569.11 EKX49410.1 - 1.2e-36 126.5 0.0 1.2e-36 126.5 0.0 2.1 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 EKX49410.1 - 1.2e-16 60.7 16.4 1.2e-05 26.0 1.2 7.6 9 0 0 9 9 9 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX49410.1 - 4.8e-08 33.2 0.4 1 9.7 0.0 6.3 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EKX49410.1 - 0.0079 16.1 0.1 2.2 8.1 0.0 4.0 4 1 1 5 5 5 1 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.10 EKX49410.1 - 0.037 13.9 0.0 0.087 12.7 0.0 1.7 1 0 0 1 1 1 0 HIRA B motif DGF-1_C PF11040.8 EKX49410.1 - 2.4 8.2 5.2 12 6.0 0.0 2.7 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Macoilin PF09726.9 EKX49410.1 - 5.6 5.4 19.2 9.8 4.6 19.2 1.3 1 0 0 1 1 1 0 Macoilin family Ank_4 PF13637.6 EKX49411.1 - 1.8e-28 98.5 2.9 3.4e-13 49.8 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX49411.1 - 1.6e-22 79.3 0.3 4.3e-09 36.5 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX49411.1 - 1.7e-22 79.8 1.0 2.2e-22 79.5 1.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX49411.1 - 1e-21 76.3 2.1 7.6e-07 29.3 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EKX49411.1 - 4.1e-17 60.5 0.6 9.5e-06 25.6 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat DUF249 PF03158.13 EKX49411.1 - 0.011 15.5 0.1 0.012 15.3 0.1 1.1 1 0 0 1 1 1 0 Multigene family 530 protein Mito_carr PF00153.27 EKX49412.1 - 3.1e-24 84.7 5.4 1.2e-09 37.9 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2478 PF10649.9 EKX49412.1 - 0.088 12.4 0.1 2.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2478) DUF1604 PF07713.13 EKX49412.1 - 0.48 10.3 1.3 8.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1604) Peptidase_S10 PF00450.22 EKX49413.1 - 1.1e-116 390.7 0.3 1.4e-116 390.3 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.8 EKX49413.1 - 0.0076 15.5 0.0 0.23 10.7 0.1 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EKX49413.1 - 0.085 12.3 0.1 0.52 9.8 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF1664 PF07889.12 EKX49414.1 - 7.6e-13 48.6 1.3 1.7e-12 47.5 0.5 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1664) Apolipoprotein PF01442.18 EKX49414.1 - 0.024 14.5 2.9 0.052 13.4 2.9 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain IFT20 PF14931.6 EKX49414.1 - 0.11 12.7 1.1 0.19 11.9 1.1 1.4 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 NPV_P10 PF05531.12 EKX49414.1 - 0.2 12.2 3.9 0.46 11.0 0.3 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Sedlin_N PF04628.13 EKX49415.1 - 7e-21 74.7 0.0 7.8e-21 74.6 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EKX49415.1 - 4.3e-06 26.7 0.0 5.1e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family TCR PF03638.15 EKX49417.1 - 2.3e-26 91.8 53.6 4.9e-13 49.2 19.6 2.1 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 EKX49417.1 - 0.041 14.0 48.1 0.15 12.2 17.0 3.0 2 2 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 PDZ_6 PF17820.1 EKX49418.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Pkinase PF00069.25 EKX49419.1 - 5.5e-77 258.7 0.0 6.3e-77 258.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX49419.1 - 4.4e-32 111.4 0.0 5.9e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EKX49419.1 - 0.00019 20.5 0.0 0.0032 16.5 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EKX49419.1 - 0.0061 15.9 0.1 0.077 12.3 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EKX49419.1 - 0.0075 15.4 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 EKX49419.1 - 0.021 14.7 0.1 0.046 13.6 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EKX49419.1 - 0.064 12.6 0.4 0.12 11.7 0.4 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_transf_41 PF13844.6 EKX49420.1 - 5.3e-56 190.0 0.0 2.7e-35 121.8 0.0 2.0 2 0 0 2 2 2 2 Glycosyl transferase family 41 DSPc PF00782.20 EKX49421.1 - 1.3e-07 31.5 0.0 1.6e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX49421.1 - 4.1e-05 23.3 0.0 5e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 EKX49421.1 - 0.029 14.1 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) cNMP_binding PF00027.29 EKX49422.1 - 3.1e-09 36.8 0.0 1.4e-05 25.1 0.0 2.3 1 1 1 2 2 2 2 Cyclic nucleotide-binding domain NAD_binding_10 PF13460.6 EKX49423.1 - 1e-09 38.5 0.0 1.6e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EKX49423.1 - 0.013 15.1 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.19 EKX49423.1 - 0.11 11.4 0.0 0.2 10.7 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RWP-RK PF02042.15 EKX49424.1 - 6.7e-15 54.8 0.2 9.6e-15 54.3 0.2 1.2 1 0 0 1 1 1 1 RWP-RK domain Sigma70_r4_2 PF08281.12 EKX49424.1 - 0.0035 17.0 0.0 0.21 11.3 0.0 2.2 2 0 0 2 2 2 2 Sigma-70, region 4 YvrJ PF12841.7 EKX49425.1 - 0.87 9.2 3.1 6.4 6.4 0.0 2.9 3 0 0 3 3 3 0 YvrJ protein family MRP-S33 PF08293.11 EKX49425.1 - 5.9 7.2 9.2 0.13 12.5 0.7 2.6 3 0 0 3 3 3 0 Mitochondrial ribosomal subunit S27 CENP-F_leu_zip PF10473.9 EKX49425.1 - 8.7 6.4 51.6 1.6 8.8 17.8 4.2 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prominin PF05478.11 EKX49426.1 - 0.5 8.3 4.2 0.9 7.4 4.2 1.4 1 0 0 1 1 1 0 Prominin Pox_A_type_inc PF04508.12 EKX49426.1 - 1.1 9.2 6.1 0.29 11.1 0.7 2.9 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Biotin_lipoyl_2 PF13533.6 EKX49426.1 - 3 7.7 5.3 96 2.9 0.0 3.5 3 0 0 3 3 3 0 Biotin-lipoyl like TSC22 PF01166.18 EKX49426.1 - 4.6 7.6 11.2 0.26 11.6 4.1 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family MORN PF02493.20 EKX49427.1 - 3.4e-15 54.9 16.5 5.3e-05 22.9 2.2 3.6 4 0 0 4 4 4 3 MORN repeat DUF3048_C PF17479.2 EKX49427.1 - 0.0076 16.6 1.8 0.14 12.6 1.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3048) C-terminal domain Whi5 PF08528.11 EKX49427.1 - 0.18 11.4 0.2 0.3 10.7 0.2 1.4 1 0 0 1 1 1 0 Whi5 like RWP-RK PF02042.15 EKX49428.1 - 6e-14 51.7 0.0 8.7e-14 51.2 0.0 1.2 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX49428.1 - 0.13 12.1 0.0 0.33 10.8 0.0 1.6 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family CitMHS PF03600.16 EKX49429.1 - 2e-44 152.0 0.0 6.1e-44 150.4 0.0 1.7 1 1 1 2 2 2 2 Citrate transporter Na_sulph_symp PF00939.19 EKX49429.1 - 3.1e-14 52.9 25.1 1.3e-12 47.6 11.5 2.3 2 0 0 2 2 2 2 Sodium:sulfate symporter transmembrane region CitMHS_2 PF16980.5 EKX49429.1 - 4.9e-05 22.2 0.4 4.9e-05 22.2 0.4 1.7 2 0 0 2 2 2 1 Putative citrate transport RBFA PF02033.18 EKX49430.1 - 3.8e-15 56.2 0.1 6.1e-15 55.6 0.1 1.3 1 0 0 1 1 1 1 Ribosome-binding factor A TPR_12 PF13424.6 EKX49431.1 - 1.4e-10 41.3 0.4 2.9e-09 37.1 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX49431.1 - 4.8e-07 29.3 0.1 0.018 14.8 0.0 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX49431.1 - 3.8e-06 26.5 0.4 0.1 12.7 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX49431.1 - 3.3e-05 23.7 0.5 0.14 12.3 0.0 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX49431.1 - 8.2e-05 22.3 0.2 0.18 11.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX49431.1 - 0.00014 21.8 0.2 0.66 10.3 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX49431.1 - 0.02 15.5 2.3 5.2 7.9 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX49431.1 - 0.037 14.9 0.2 14 6.8 0.0 3.1 1 1 1 2 2 2 0 Tetratricopeptide repeat p450 PF00067.22 EKX49432.1 - 4.5e-78 263.0 0.0 5.1e-78 262.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 KSHV_K8 PF07188.11 EKX49432.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Kaposi's sarcoma-associated herpesvirus (KSHV) K8 protein HAGH_C PF16123.5 EKX49433.1 - 5.2e-28 97.4 0.1 7.4e-28 96.9 0.1 1.2 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EKX49433.1 - 9.7e-17 61.6 1.4 3e-16 60.0 1.4 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EKX49433.1 - 0.063 12.8 0.1 0.095 12.2 0.1 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain EF-hand_7 PF13499.6 EKX49434.1 - 2.7e-14 53.4 1.3 3.1e-08 33.9 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX49434.1 - 2.3e-09 36.4 0.1 0.00017 21.3 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EKX49434.1 - 7.1e-09 34.6 1.3 0.00034 20.0 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 EKX49434.1 - 9.8e-07 29.0 0.0 0.0034 17.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EKX49434.1 - 5.8e-05 22.4 0.1 0.00089 18.7 0.0 2.5 2 0 0 2 2 2 1 EF hand Sigma54_CBD PF04963.13 EKX49434.1 - 0.0048 16.8 0.7 0.52 10.1 0.4 2.6 1 1 2 3 3 3 1 Sigma-54 factor, core binding domain EFhand_Ca_insen PF08726.10 EKX49434.1 - 0.0051 16.9 0.7 0.01 15.9 0.7 1.5 1 0 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_8 PF13833.6 EKX49434.1 - 0.013 15.3 2.9 0.88 9.5 0.2 3.1 2 1 1 3 3 3 0 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX49434.1 - 0.016 15.6 0.3 0.043 14.1 0.3 1.9 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region IMPDH PF00478.25 EKX49436.1 - 1.8e-131 438.3 4.5 2.1e-131 438.1 4.5 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EKX49436.1 - 3.5e-18 65.8 0.2 1.2e-10 41.6 0.0 2.8 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 EKX49436.1 - 7.2e-14 51.9 0.1 9.5e-09 35.1 0.1 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 EKX49436.1 - 4.5e-09 35.8 0.2 1.1e-08 34.5 0.2 1.6 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 EKX49436.1 - 2.6e-06 27.1 0.2 9.3e-05 22.0 0.0 2.6 2 1 1 3 3 3 1 Histidine biosynthesis protein ThiG PF05690.14 EKX49436.1 - 3.7e-06 26.4 0.7 1.8e-05 24.2 0.7 2.0 1 1 0 1 1 1 1 Thiazole biosynthesis protein ThiG NanE PF04131.14 EKX49436.1 - 1.7e-05 24.1 0.1 4.3e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase DHO_dh PF01180.21 EKX49436.1 - 0.0004 19.7 0.9 0.0042 16.4 0.1 2.3 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase Dus PF01207.17 EKX49436.1 - 0.00081 18.6 0.5 0.21 10.7 0.0 2.4 1 1 0 2 2 2 2 Dihydrouridine synthase (Dus) DUF561 PF04481.12 EKX49436.1 - 0.0016 17.7 0.0 0.96 8.6 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF561) Glu_synthase PF01645.17 EKX49436.1 - 0.0025 17.0 1.2 0.01 15.0 0.3 2.3 2 1 1 3 3 3 1 Conserved region in glutamate synthase G3P_antiterm PF04309.12 EKX49436.1 - 0.0051 16.3 0.2 0.073 12.5 0.0 2.4 2 0 0 2 2 2 1 Glycerol-3-phosphate responsive antiterminator EAL PF00563.20 EKX49436.1 - 0.0052 16.3 0.2 0.53 9.8 0.2 2.4 2 1 0 2 2 2 1 EAL domain Aldolase PF01081.19 EKX49436.1 - 0.015 14.7 0.2 0.18 11.2 0.1 2.3 2 0 0 2 2 2 0 KDPG and KHG aldolase B12-binding PF02310.19 EKX49436.1 - 0.023 14.7 0.2 0.096 12.7 0.1 2.1 2 0 0 2 2 2 0 B12 binding domain QRPTase_C PF01729.19 EKX49436.1 - 0.093 12.5 0.1 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain GATase PF00117.28 EKX49437.1 - 1e-36 126.5 0.0 2.3e-36 125.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 EKX49437.1 - 1.1e-18 67.0 0.0 2.4e-12 46.7 0.0 2.9 2 1 0 2 2 2 2 GMP synthase C terminal domain Peptidase_C26 PF07722.13 EKX49437.1 - 1.3e-12 48.0 0.0 2.8e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 EKX49437.1 - 2.7e-11 43.1 0.0 3.9e-08 32.7 0.0 2.4 2 0 0 2 2 2 2 NAD synthase QueC PF06508.13 EKX49437.1 - 1.5e-07 31.2 0.0 2e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 EKX49437.1 - 6e-05 23.1 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family tRNA_Me_trans PF03054.16 EKX49437.1 - 0.00031 19.7 0.1 0.0013 17.6 0.1 1.9 2 0 0 2 2 2 1 tRNA methyl transferase ATP_bind_3 PF01171.20 EKX49437.1 - 0.00075 19.3 0.2 0.0021 17.8 0.2 1.7 2 0 0 2 2 2 1 PP-loop family Asn_synthase PF00733.21 EKX49437.1 - 0.00083 19.1 0.1 0.0014 18.3 0.1 1.3 1 0 0 1 1 1 1 Asparagine synthase Arginosuc_synth PF00764.19 EKX49437.1 - 0.0083 15.5 0.1 0.013 14.8 0.1 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase ThiI PF02568.14 EKX49437.1 - 0.053 13.1 0.1 0.13 11.8 0.1 1.7 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) GATase_3 PF07685.14 EKX49437.1 - 0.11 12.1 0.1 0.32 10.6 0.1 1.7 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain PDZ_1 PF12812.7 EKX49437.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 PDZ-like domain MIP PF00230.20 EKX49438.1 - 4.3e-45 154.2 15.5 5.4e-45 153.8 15.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF485 PF04341.12 EKX49438.1 - 0.0044 16.9 5.7 0.011 15.6 0.8 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF485 Tubulin_2 PF13809.6 EKX49438.1 - 0.058 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Tubulin like PKD_channel PF08016.12 EKX49439.1 - 8.8e-37 126.8 10.7 1.4e-36 126.1 10.7 1.3 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 EKX49439.1 - 3.3e-11 42.9 15.2 3.3e-11 42.9 15.2 2.5 2 1 0 2 2 2 1 Ion transport protein ELO PF01151.18 EKX49439.1 - 0.00099 18.7 2.7 0.00099 18.7 2.7 2.0 1 1 1 2 2 2 1 GNS1/SUR4 family CHASE PF03924.13 EKX49440.1 - 1e-10 41.9 0.0 2.5e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 CHASE domain Ion_trans_2 PF07885.16 EKX49441.1 - 2.3e-08 33.9 7.1 5.6e-08 32.6 7.1 1.6 1 0 0 1 1 1 1 Ion channel SK_channel PF03530.14 EKX49441.1 - 0.0012 18.8 0.1 0.45 10.5 0.0 2.7 2 0 0 2 2 2 2 Calcium-activated SK potassium channel Kinesin PF00225.23 EKX49442.1 - 9e-92 307.5 0.0 1.1e-91 307.3 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX49442.1 - 4.1e-20 72.2 0.0 8.1e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding SOR_SNZ PF01680.17 EKX49445.1 - 8.8e-110 365.3 7.8 1.1e-109 365.0 7.3 1.4 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.14 EKX49445.1 - 1.9e-07 30.7 6.4 2.8e-06 26.8 0.2 2.7 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 EKX49445.1 - 2.7e-05 23.4 0.3 0.1 11.6 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) TetR_C_27 PF17935.1 EKX49445.1 - 0.0021 18.1 0.0 0.0052 16.8 0.0 1.7 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain NanE PF04131.14 EKX49445.1 - 0.0057 15.9 1.5 0.12 11.6 0.0 2.9 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase IMPDH PF00478.25 EKX49445.1 - 0.013 14.5 0.4 0.021 13.9 0.4 1.4 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain IGPS PF00218.21 EKX49445.1 - 0.023 13.9 0.1 0.61 9.2 0.0 2.5 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase His_biosynth PF00977.21 EKX49445.1 - 0.023 14.1 0.3 0.71 9.3 0.0 2.7 2 1 1 3 3 3 0 Histidine biosynthesis protein OMPdecase PF00215.24 EKX49445.1 - 0.056 13.0 0.7 0.32 10.6 0.2 2.3 2 1 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family UQ_con PF00179.26 EKX49446.1 - 5.6e-51 171.9 0.0 1.3e-27 96.1 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme UEV PF05743.13 EKX49446.1 - 0.0012 18.7 0.0 0.0036 17.1 0.0 1.7 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 EKX49446.1 - 0.0048 17.2 0.0 1 9.6 0.0 2.5 2 0 0 2 2 2 2 RWD domain DUF3884 PF13024.6 EKX49446.1 - 0.039 13.5 0.3 4.2 7.0 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3884) cNMP_binding PF00027.29 EKX49447.1 - 2.9e-15 56.1 0.1 0.00016 21.7 0.0 6.0 5 2 0 5 5 5 3 Cyclic nucleotide-binding domain C2 PF00168.30 EKX49447.1 - 3.5e-06 27.2 0.0 1.3e-05 25.4 0.0 2.0 1 0 0 1 1 1 1 C2 domain IQ PF00612.27 EKX49447.1 - 0.069 13.0 7.0 1.3 9.0 0.8 2.9 2 0 0 2 2 2 0 IQ calmodulin-binding motif RRM_1 PF00076.22 EKX49448.1 - 8.2e-08 32.0 0.0 1.6e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 EKX49448.1 - 0.012 15.6 5.1 0.017 15.2 5.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit OMS28_porin PF03532.13 EKX49448.1 - 0.076 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 OMS28 porin PDZ_2 PF13180.6 EKX49449.1 - 0.022 15.1 0.1 0.028 14.7 0.1 1.2 1 0 0 1 1 1 0 PDZ domain FG-GAP_2 PF14312.6 EKX49450.1 - 1.8e-14 53.7 30.8 0.062 13.6 0.1 8.9 8 0 0 8 8 8 6 FG-GAP repeat F5_F8_type_C PF00754.25 EKX49450.1 - 2e-11 44.1 0.0 4e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 F5/8 type C domain Laminin_G_3 PF13385.6 EKX49450.1 - 6.6e-06 26.3 0.0 4.2e-05 23.7 0.0 2.4 2 1 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Fibrinogen_C PF00147.18 EKX49450.1 - 0.0014 18.5 0.1 0.0027 17.5 0.1 1.4 1 0 0 1 1 1 1 Fibrinogen beta and gamma chains, C-terminal globular domain RTBV_P46 PF06216.11 EKX49451.1 - 1.8 7.4 7.8 0.21 10.4 1.0 2.3 2 1 1 3 3 3 0 Rice tungro bacilliform virus P46 protein PIG-L PF02585.17 EKX49452.1 - 7.1e-24 84.9 0.0 1.1e-23 84.3 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase FKBP_C PF00254.28 EKX49453.1 - 2e-19 69.7 0.0 3e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Glycos_transf_1 PF00534.20 EKX49454.1 - 4.7e-21 75.1 0.0 5.4e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EKX49454.1 - 3.8e-16 59.7 0.2 4.8e-16 59.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EKX49454.1 - 6.6e-12 45.7 0.0 7.8e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EKX49455.1 - 4.7e-21 75.1 0.0 5.4e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EKX49455.1 - 3.8e-16 59.7 0.2 4.8e-16 59.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EKX49455.1 - 6.6e-12 45.7 0.0 7.8e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Ribosomal_L10 PF00466.20 EKX49456.1 - 3.3e-19 68.9 0.0 5.2e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 EKX49456.1 - 1e-18 67.1 0.1 1.8e-18 66.3 0.1 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P ABC_tran PF00005.27 EKX49457.1 - 1.8e-53 180.7 0.1 1.6e-28 99.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EKX49457.1 - 6.8e-22 77.3 16.9 9.6e-20 70.4 3.6 3.2 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 EKX49457.1 - 2.6e-12 47.2 3.3 0.0024 17.7 0.1 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EKX49457.1 - 6.5e-09 35.5 5.7 0.00024 20.6 0.1 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EKX49457.1 - 2.8e-05 23.7 0.1 0.013 15.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EKX49457.1 - 6.1e-05 23.0 0.2 0.0084 16.0 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 EKX49457.1 - 0.00014 21.6 0.3 0.54 10.0 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.6 EKX49457.1 - 0.00045 20.6 0.0 0.96 9.8 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 EKX49457.1 - 0.00056 19.9 0.0 0.26 11.2 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 EKX49457.1 - 0.00063 20.0 4.8 0.0073 16.6 0.0 3.6 2 2 1 3 3 3 1 AAA domain AAA PF00004.29 EKX49457.1 - 0.0012 19.3 0.2 0.32 11.4 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EKX49457.1 - 0.0017 18.9 0.9 0.32 11.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.23 EKX49457.1 - 0.0025 17.9 0.0 0.26 11.4 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 EKX49457.1 - 0.0034 17.1 0.0 0.0034 17.1 0.0 3.5 4 2 0 5 5 4 1 AAA ATPase domain AAA_33 PF13671.6 EKX49457.1 - 0.0038 17.4 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EKX49457.1 - 0.004 17.4 0.2 2.8 8.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.23 EKX49457.1 - 0.0052 16.9 0.1 0.39 10.8 0.0 2.7 3 0 0 3 3 2 1 Dynamin family AAA_14 PF13173.6 EKX49457.1 - 0.0062 16.6 0.0 3.7 7.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EKX49457.1 - 0.0067 16.9 0.0 0.0067 16.9 0.0 4.0 3 1 1 4 4 4 1 AAA domain THOC7 PF05615.13 EKX49457.1 - 0.0078 16.5 6.2 0.07 13.4 0.5 2.4 2 0 0 2 2 2 1 Tho complex subunit 7 AAA_30 PF13604.6 EKX49457.1 - 0.017 14.8 0.0 2.2 8.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EKX49457.1 - 0.028 14.4 0.6 27 4.6 0.0 3.9 3 1 1 4 4 4 0 NTPase CCDC-167 PF15188.6 EKX49457.1 - 0.031 14.6 0.4 0.092 13.1 0.4 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 AAA_25 PF13481.6 EKX49457.1 - 0.032 13.8 0.2 1.5 8.4 0.0 2.8 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.15 EKX49457.1 - 0.038 13.9 0.0 1 9.2 0.0 2.8 2 1 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 EKX49457.1 - 0.054 13.9 0.1 2.2 8.7 0.0 2.8 3 0 0 3 3 2 0 RNA helicase TsaE PF02367.17 EKX49457.1 - 0.084 12.9 0.2 6.3 6.8 0.0 2.6 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE XhlA PF10779.9 EKX49457.1 - 0.095 12.9 4.7 0.19 11.9 0.2 2.8 2 0 0 2 2 2 0 Haemolysin XhlA DUF4349 PF14257.6 EKX49457.1 - 0.097 12.1 1.3 0.1 12.1 0.2 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4349) Snapin_Pallidin PF14712.6 EKX49457.1 - 0.1 13.0 0.4 0.1 13.0 0.4 1.8 2 0 0 2 2 1 0 Snapin/Pallidin AAA_27 PF13514.6 EKX49457.1 - 0.11 12.1 0.4 6.3 6.3 0.0 3.0 2 1 1 3 3 3 0 AAA domain AAA_7 PF12775.7 EKX49457.1 - 0.12 11.9 0.0 5.2 6.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP-synt_ab PF00006.25 EKX49457.1 - 0.12 12.0 0.2 6.8 6.3 0.0 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.14 EKX49457.1 - 0.14 12.2 0.2 3.6 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma70_r1_1 PF03979.14 EKX49457.1 - 0.37 10.9 0.0 0.37 10.9 0.0 2.7 3 0 0 3 3 3 0 Sigma-70 factor, region 1.1 FtsK_SpoIIIE PF01580.18 EKX49457.1 - 0.6 9.4 2.5 17 4.6 0.0 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family BicD PF09730.9 EKX49457.1 - 0.68 8.3 7.3 0.47 8.8 0.5 2.1 2 0 0 2 2 2 0 Microtubule-associated protein Bicaudal-D TPR_MLP1_2 PF07926.12 EKX49457.1 - 1.8 8.6 9.9 1.5 8.9 1.2 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3584 PF12128.8 EKX49457.1 - 3.7 4.9 13.8 1.1 6.7 0.4 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3584) Acetyltransf_1 PF00583.25 EKX49458.1 - 9.8e-07 29.0 0.0 1.5e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EKX49458.1 - 0.0025 17.8 0.0 0.0059 16.6 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EKX49458.1 - 0.025 15.0 0.0 0.046 14.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EKX49458.1 - 0.076 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 EKX49458.1 - 0.1 12.6 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EKX49458.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Zn_clus PF00172.18 EKX49460.1 - 5e-13 48.9 34.3 1.9e-07 31.1 12.0 2.2 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Presenilin PF01080.17 EKX49462.1 - 1.5 7.5 4.7 1.8 7.2 4.7 1.1 1 0 0 1 1 1 0 Presenilin GalP_UDP_transf PF01087.22 EKX49463.1 - 7.4e-13 49.3 0.2 1.6e-12 48.2 0.2 1.5 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF4931 PF16285.5 EKX49463.1 - 1.4e-08 34.4 0.4 7.7e-08 31.9 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4931) GalP_UDP_tr_C PF02744.17 EKX49463.1 - 4.4e-07 29.8 0.2 1.2e-06 28.3 0.0 1.8 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4921 PF16268.5 EKX49463.1 - 1.5e-06 27.3 0.7 1.4e-05 24.1 0.1 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4921) Y_phosphatase2 PF03162.13 EKX49463.1 - 0.011 15.3 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family F-box-like PF12937.7 EKX49465.1 - 0.00011 22.0 1.1 0.00011 22.0 1.1 2.6 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 EKX49465.1 - 0.00024 21.4 0.6 0.22 12.0 0.0 3.2 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) F-box PF00646.33 EKX49465.1 - 0.022 14.6 13.2 0.037 13.9 3.0 3.2 3 0 0 3 3 3 0 F-box domain LRR_8 PF13855.6 EKX49465.1 - 0.025 14.3 0.1 0.23 11.3 0.0 2.4 2 0 0 2 2 2 0 Leucine rich repeat LRR_6 PF13516.6 EKX49465.1 - 0.13 12.4 0.2 6.8 7.0 0.0 3.4 4 0 0 4 4 4 0 Leucine Rich repeat P_C10 PF14974.6 EKX49466.1 - 1.7e-17 63.4 0.0 1.9e-17 63.2 0.0 1.0 1 0 0 1 1 1 1 Protein C10 BRE PF06113.12 EKX49466.1 - 0.04 12.8 0.0 0.046 12.6 0.0 1.0 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) ATS3 PF06232.11 EKX49466.1 - 0.15 11.9 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Embryo-specific protein 3, (ATS3) DUF1538 PF07556.11 EKX49467.1 - 3.9e-104 346.5 49.7 4.1e-53 179.8 18.2 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1538) DUF1336 PF07059.12 EKX49469.1 - 1.3e-42 146.4 0.0 1.5e-42 146.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) PhoPQ_related PF10142.9 EKX49469.1 - 0.14 10.8 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Ion_trans PF00520.31 EKX49470.1 - 1.9e-07 30.6 5.7 2.7e-07 30.1 5.7 1.1 1 0 0 1 1 1 1 Ion transport protein STIMATE PF12400.8 EKX49470.1 - 0.2 12.2 2.2 0.39 11.3 2.2 1.4 1 0 0 1 1 1 0 STIMATE family CCB2_CCB4 PF11152.8 EKX49473.1 - 0.0077 15.6 0.2 0.011 15.1 0.2 1.2 1 0 0 1 1 1 1 Cofactor assembly of complex C subunit B, CCB2/CCB4 G10 PF01125.17 EKX49473.1 - 0.043 13.6 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 G10 protein SLATT_5 PF18160.1 EKX49473.1 - 0.12 11.7 0.4 0.18 11.1 0.4 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Radial_spoke_3 PF06098.11 EKX49474.1 - 0.013 14.8 12.6 0.013 14.8 12.6 2.0 2 1 0 2 2 2 0 Radial spoke protein 3 MRPL52 PF18699.1 EKX49474.1 - 4.5 7.5 10.5 12 6.2 10.5 1.7 1 0 0 1 1 1 0 Mitoribosomal protein mL52 GET2 PF08690.10 EKX49475.1 - 0.063 13.0 8.3 0.1 12.3 8.3 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Cys_rich_FGFR PF00839.17 EKX49476.1 - 0.0032 17.6 4.0 0.68 10.1 0.6 2.7 2 1 0 2 2 2 2 Cysteine rich repeat Trypan_PARP PF05887.11 EKX49476.1 - 0.092 12.7 9.1 0.16 12.0 9.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PseudoU_synth_2 PF00849.22 EKX49477.1 - 2.3e-13 50.5 0.0 7.6e-13 48.9 0.0 1.8 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 EKX49477.1 - 4.9e-08 32.6 0.0 1.3e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 EKX49477.1 - 0.12 12.2 0.3 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 S4 domain NifU PF01106.17 EKX49478.1 - 6.5e-20 71.0 0.0 1.2e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 EKX49478.1 - 2.2e-16 59.7 0.0 4.1e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal CHRD PF07452.12 EKX49479.1 - 6.8e-07 30.3 0.0 1.4e-06 29.3 0.0 1.6 1 1 0 1 1 1 1 CHRD domain NDK PF00334.19 EKX49482.1 - 1e-53 181.0 0.0 1.1e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Thioredoxin_4 PF13462.6 EKX49484.1 - 0.0011 19.1 0.0 1.1 9.4 0.0 2.0 1 1 1 2 2 2 2 Thioredoxin Thioredoxin PF00085.20 EKX49484.1 - 0.0024 17.8 0.0 0.0031 17.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.24 EKX49484.1 - 0.019 15.2 0.1 0.028 14.6 0.1 1.3 1 0 0 1 1 1 0 Glutaredoxin zf-FPG_IleRS PF06827.14 EKX49484.1 - 0.019 14.8 0.1 0.029 14.2 0.1 1.3 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS L_lactis_RepB_C PF06430.12 EKX49484.1 - 0.035 14.1 0.1 0.071 13.1 0.1 1.5 2 0 0 2 2 2 0 Lactococcus lactis RepB C-terminus DUF2201_N PF13203.6 EKX49485.1 - 3.7 7.1 6.1 4.4 6.8 6.1 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain SNARE_assoc PF09335.11 EKX49486.1 - 7.4e-07 29.7 1.5 2.1e-06 28.2 0.0 2.6 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF373 PF04123.13 EKX49486.1 - 0.00069 19.2 1.7 0.1 12.0 0.5 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF373) MAP65_ASE1 PF03999.12 EKX49486.1 - 2 7.0 15.9 2.8 6.5 15.9 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) SOG2 PF10428.9 EKX49486.1 - 2.6 7.1 9.3 3.3 6.8 9.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PAP2_C PF14360.6 EKX49487.1 - 2.6e-25 88.7 6.3 2.6e-25 88.7 6.3 1.8 2 0 0 2 2 2 1 PAP2 superfamily C-terminal SAM_1 PF00536.30 EKX49487.1 - 5e-06 26.9 0.0 9.3e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EKX49487.1 - 8.1e-05 22.7 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PAP2 PF01569.21 EKX49487.1 - 0.0014 18.4 8.2 0.003 17.3 8.0 1.4 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 EKX49487.1 - 0.013 15.2 3.4 0.021 14.5 3.4 1.3 1 0 0 1 1 1 0 PAP2 superfamily SAM_3 PF18016.1 EKX49487.1 - 0.092 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 EKX49487.1 - 0.13 12.2 0.0 0.43 10.6 0.0 1.8 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain CTP_transf_1 PF01148.20 EKX49488.1 - 0.00091 19.1 3.2 0.0014 18.4 3.2 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family MORN PF02493.20 EKX49489.1 - 7.7e-87 280.3 94.9 7e-08 31.9 0.7 15.8 15 1 0 15 15 15 15 MORN repeat Anti-TRAP PF15777.5 EKX49489.1 - 0.96 9.5 5.1 8.8 6.4 0.1 4.1 4 0 0 4 4 4 0 Tryptophan RNA-binding attenuator protein inhibitory protein Defensin_1 PF00323.19 EKX49489.1 - 2.7 8.6 4.1 1.2e+02 3.4 0.1 3.7 3 0 0 3 3 3 0 Mammalian defensin SM-ATX PF14438.6 EKX49489.1 - 4 7.6 15.3 12 6.2 0.1 6.2 7 1 0 7 7 7 0 Ataxin 2 SM domain MORN PF02493.20 EKX49490.1 - 0.00064 19.5 7.2 0.014 15.2 0.3 3.4 4 0 0 4 4 4 2 MORN repeat PseudoU_synth_2 PF00849.22 EKX49491.1 - 1.3e-07 31.9 0.0 2.7e-07 30.8 0.0 1.5 1 1 0 1 1 1 1 RNA pseudouridylate synthase ProRS-C_1 PF09180.11 EKX49493.1 - 4e-23 81.4 1.2 4e-23 81.4 1.2 2.1 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA_edit PF04073.15 EKX49493.1 - 2.3e-21 76.2 0.0 4.9e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HGTP_anticodon PF03129.20 EKX49493.1 - 1.7e-20 73.0 0.1 4.6e-19 68.4 0.1 2.6 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EKX49493.1 - 2.6e-20 73.2 0.0 5.8e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) LRR_8 PF13855.6 EKX49494.1 - 1.6e-33 114.3 43.3 9.8e-09 34.9 3.4 4.7 2 1 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 EKX49494.1 - 5.1e-22 77.6 30.1 5.9e-06 26.5 0.7 6.4 3 2 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX49494.1 - 4.1e-07 29.7 32.2 0.51 11.1 0.7 9.1 10 0 0 10 10 10 4 Leucine Rich Repeat LRR_9 PF14580.6 EKX49494.1 - 4.4e-06 26.3 10.9 0.00078 19.0 1.4 2.7 1 1 2 3 3 3 3 Leucine-rich repeat Amino_oxidase PF01593.24 EKX49496.1 - 1.1e-53 183.2 0.0 1.2e-53 183.0 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EKX49496.1 - 5.9e-14 52.0 0.3 1.4e-13 50.8 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain MCRA PF06100.11 EKX49496.1 - 3.1e-08 32.8 0.0 0.00031 19.7 0.0 2.1 2 0 0 2 2 2 2 MCRA family Pyr_redox_2 PF07992.14 EKX49496.1 - 2.4e-05 23.7 0.1 0.003 16.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EKX49496.1 - 3.7e-05 24.2 0.5 0.11 13.1 0.5 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EKX49496.1 - 0.00025 20.3 0.2 0.021 13.9 0.7 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EKX49496.1 - 0.00046 19.9 1.5 0.024 14.2 0.6 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EKX49496.1 - 0.0082 14.9 2.2 0.015 14.0 0.8 2.1 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.7 EKX49496.1 - 0.014 14.8 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EKX49496.1 - 0.072 12.3 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain FtsX PF02687.21 EKX49497.1 - 0.24 11.9 6.2 0.057 13.9 2.3 1.9 1 1 1 2 2 2 0 FtsX-like permease family RWP-RK PF02042.15 EKX49498.1 - 4.2e-14 52.2 0.1 7e-14 51.5 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain Sigma70_r4_2 PF08281.12 EKX49498.1 - 0.046 13.4 0.2 0.08 12.6 0.0 1.5 2 0 0 2 2 2 0 Sigma-70, region 4 RWP-RK PF02042.15 EKX49499.1 - 5.3e-14 51.9 0.1 8.6e-14 51.3 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain Sigma70_r4_2 PF08281.12 EKX49499.1 - 0.058 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 RWP-RK PF02042.15 EKX49500.1 - 3.6e-14 52.5 0.5 9.4e-14 51.1 0.1 1.8 2 0 0 2 2 2 1 RWP-RK domain Sigma70_r4_2 PF08281.12 EKX49500.1 - 0.052 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 DUF4131 PF13567.6 EKX49501.1 - 0.27 10.9 2.8 0.31 10.7 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) CCDC53 PF10152.9 EKX49502.1 - 0.045 14.2 0.8 0.06 13.8 0.8 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex MttA_Hcf106 PF02416.16 EKX49502.1 - 0.081 12.3 0.1 0.2 11.0 0.1 1.6 1 0 0 1 1 1 0 mttA/Hcf106 family HEAT_2 PF13646.6 EKX49503.1 - 1.1e-12 48.1 11.4 0.0004 20.7 0.9 3.9 1 1 4 5 5 5 5 HEAT repeats HEAT PF02985.22 EKX49503.1 - 3e-06 27.0 2.2 4.3 7.9 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 EKX49503.1 - 3.1e-06 27.3 8.1 0.00085 19.4 1.1 3.0 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 TetR_C_10 PF16295.5 EKX49503.1 - 0.0031 17.8 0.0 0.008 16.5 0.0 1.7 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain RTP1_C1 PF10363.9 EKX49503.1 - 0.014 15.6 6.9 0.12 12.6 0.3 3.6 1 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 TAF6_C PF07571.13 EKX49503.1 - 0.035 14.4 0.7 4.3 7.7 0.0 2.9 2 1 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain DUF2937 PF11157.8 EKX49503.1 - 0.062 13.0 1.1 0.14 11.9 0.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) Death PF00531.22 EKX49503.1 - 0.073 13.2 1.8 2.5 8.3 0.5 2.6 2 0 0 2 2 2 0 Death domain OST_P2 PF18235.1 EKX49503.1 - 0.13 12.2 0.3 0.66 9.9 0.1 2.1 2 0 0 2 2 2 0 Oligosaccharyltransferase Peripheral 2 domain HEAT_EZ PF13513.6 EKX49503.1 - 0.18 12.3 3.4 11 6.7 0.2 3.8 2 1 2 4 4 4 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EKX49503.1 - 0.21 12.2 1.4 3.2 8.4 0.0 2.8 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region Terminase_2 PF03592.16 EKX49503.1 - 4.5 7.7 7.1 32 5.0 7.1 2.1 1 1 0 1 1 1 0 Terminase small subunit UCH PF00443.29 EKX49504.1 - 1.8e-50 171.8 0.0 2.2e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EKX49504.1 - 3e-18 66.5 0.1 6.9e-16 58.7 0.1 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-HIT PF04438.16 EKX49504.1 - 2.5 8.0 9.7 0.082 12.8 2.1 2.4 2 0 0 2 2 2 0 HIT zinc finger RRM_1 PF00076.22 EKX49505.1 - 3e-05 23.7 0.0 4.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) X PF00739.19 EKX49505.1 - 0.79 9.9 3.0 19 5.4 0.0 2.9 1 1 1 3 3 3 0 Trans-activation protein X Bacillus_HBL PF05791.11 EKX49506.1 - 0.14 12.0 6.9 0.087 12.6 1.9 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Mt_ATP-synt_D PF05873.12 EKX49506.1 - 0.34 10.8 9.2 0.12 12.2 1.4 2.2 1 1 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Jnk-SapK_ap_N PF09744.9 EKX49506.1 - 0.55 10.4 24.8 0.032 14.5 7.2 2.2 1 1 0 2 2 2 0 JNK_SAPK-associated protein-1 TPR_MLP1_2 PF07926.12 EKX49506.1 - 0.9 9.6 27.5 0.44 10.6 9.7 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Noelin-1 PF12308.8 EKX49506.1 - 2.6 8.1 10.8 0.33 11.0 3.8 2.6 2 1 1 3 3 3 0 Neurogenesis glycoprotein DUF1664 PF07889.12 EKX49506.1 - 2.8 8.0 13.0 12 5.9 2.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) YscO PF07321.12 EKX49506.1 - 4.2 7.3 31.8 0.9 9.5 9.7 2.1 1 1 1 2 2 2 0 Type III secretion protein YscO DUF812 PF05667.11 EKX49506.1 - 6.4 5.5 23.2 74 2.0 23.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) LMBR1 PF04791.16 EKX49506.1 - 6.9 5.5 9.0 8.5 5.2 9.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FUSC PF04632.12 EKX49506.1 - 7.7 4.9 14.8 1.7 7.1 2.9 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family GREB1 PF15782.5 EKX49507.1 - 0.0042 14.3 30.1 0.005 14.1 30.1 1.2 1 0 0 1 1 1 1 Gene regulated by oestrogen in breast cancer Mem_trans PF03547.18 EKX49507.1 - 0.26 9.7 11.5 0.38 9.1 11.5 1.2 1 0 0 1 1 1 0 Membrane transport protein Dapper PF15268.6 EKX49507.1 - 0.34 9.7 41.2 0.53 9.1 41.2 1.3 1 0 0 1 1 1 0 Dapper Endostatin PF06482.11 EKX49507.1 - 7 6.0 39.1 0.87 9.0 34.1 1.9 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin DUF966 PF06136.13 EKX49507.1 - 8.1 6.1 36.7 15 5.1 36.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF966) tRNA-synt_2 PF00152.20 EKX49508.1 - 1.4e-74 251.1 0.0 1.5e-73 247.6 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EKX49508.1 - 3.4e-09 36.5 0.0 7.2e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EKX49508.1 - 0.02 14.4 0.2 0.63 9.5 0.0 2.5 2 1 0 2 2 2 0 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.20 EKX49509.1 - 2e-54 184.8 0.0 8.4e-54 182.8 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EKX49509.1 - 2.6e-09 36.9 0.0 9.9e-09 35.1 0.0 2.0 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain KH_1 PF00013.29 EKX49510.1 - 4.8e-110 359.5 41.8 4e-14 52.2 2.5 15.0 15 0 0 15 15 15 13 KH domain SLS PF14611.6 EKX49510.1 - 5.1e-20 72.2 9.1 0.0011 18.9 1.1 8.2 3 3 5 8 8 8 7 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 EKX49510.1 - 6.3e-14 51.6 35.8 0.003 17.3 0.6 10.8 9 2 2 11 11 11 6 KH domain MOEP19 PF16005.5 EKX49510.1 - 8.6e-13 48.1 5.1 0.23 11.5 0.0 8.7 6 1 2 8 8 8 3 KH-like RNA-binding domain KH_5 PF13184.6 EKX49510.1 - 4.7e-05 23.4 21.1 0.51 10.5 0.0 8.9 9 0 0 9 9 9 2 NusA-like KH domain KH_4 PF13083.6 EKX49510.1 - 0.00081 19.2 4.4 0.018 14.9 0.3 4.6 4 0 0 4 4 4 1 KH domain PTS_2-RNA PF01885.16 EKX49510.1 - 0.056 13.5 0.3 5.6 7.0 0.0 2.8 1 1 1 2 2 2 0 RNA 2'-phosphotransferase, Tpt1 / KptA family ER_lumen_recept PF00810.18 EKX49511.1 - 1.4e-50 171.9 6.6 2.2e-50 171.3 6.6 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EKX49511.1 - 0.69 9.7 17.8 0.29 10.9 0.4 4.8 4 1 1 5 5 5 0 PQ loop repeat Ribosomal_L37e PF01907.19 EKX49512.1 - 2e-19 69.5 11.3 3.6e-19 68.7 11.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DUF2688 PF10892.8 EKX49512.1 - 0.051 13.0 2.3 0.094 12.2 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) HypA PF01155.19 EKX49512.1 - 0.29 11.2 1.6 0.46 10.5 1.6 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FeS PF04060.13 EKX49512.1 - 1.9 8.2 7.1 0.89 9.3 2.8 2.2 2 0 0 2 2 2 0 Putative Fe-S cluster RVT_1 PF00078.27 EKX49513.1 - 1.8e-08 34.2 0.1 3.4e-08 33.3 0.1 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CK2S PF15011.6 EKX49514.1 - 0.06 13.2 0.0 0.069 13.0 0.0 1.1 1 0 0 1 1 1 0 Casein Kinase 2 substrate DUF5122 PF17164.4 EKX49515.1 - 0.18 12.1 7.8 1.4 9.3 0.4 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller PQQ_3 PF13570.6 EKX49515.1 - 5.4 7.6 11.4 3 8.5 0.1 4.3 5 0 0 5 5 5 0 PQQ-like domain SpoVAE PF14097.6 EKX49516.1 - 0.18 11.4 0.1 0.28 10.8 0.1 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AE1 TP53IP5 PF15331.6 EKX49516.1 - 0.3 11.2 5.0 0.048 13.8 1.2 1.5 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 TFIIA PF03153.13 EKX49516.1 - 7.6 6.4 32.4 5 7.0 11.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ank_2 PF12796.7 EKX49517.1 - 4.2e-18 65.7 0.1 3.2e-12 46.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX49517.1 - 8.3e-13 48.6 0.1 2e-09 37.8 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX49517.1 - 1.2e-12 47.8 0.4 8.4e-05 22.8 0.0 3.6 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX49517.1 - 3.4e-12 46.2 1.0 0.00033 21.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EKX49517.1 - 5.4e-11 41.7 0.1 0.0023 18.3 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ras_bdg_2 PF14847.6 EKX49517.1 - 0.035 14.4 0.2 0.18 12.1 0.1 1.9 1 1 1 2 2 2 0 Ras-binding domain of Byr2 Lip_prot_lig_C PF10437.9 EKX49519.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus DASH_Dad1 PF08649.10 EKX49519.1 - 0.2 11.9 0.2 0.38 11.0 0.2 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad1 Pkinase PF00069.25 EKX49520.1 - 8.1e-67 225.4 0.1 9.3e-67 225.2 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX49520.1 - 4.8e-45 153.9 0.1 5.9e-45 153.6 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX49520.1 - 1.7e-10 40.3 0.0 7e-10 38.2 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EKX49520.1 - 7.1e-05 22.8 0.1 0.00097 19.1 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EKX49520.1 - 0.00046 19.8 0.0 0.00074 19.2 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EKX49520.1 - 0.0073 15.3 0.0 0.013 14.4 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain DnaJ_CXXCXGXG PF00684.19 EKX49521.1 - 0.00047 20.5 1.9 0.0007 19.9 1.9 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EKX49521.1 - 1.5 8.8 5.1 2.7 8.0 4.3 1.9 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein COX15-CtaA PF02628.15 EKX49522.1 - 1.8e-96 323.0 11.0 2.1e-96 322.8 11.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein PPV_E2_C PF00511.17 EKX49522.1 - 0.062 13.5 0.1 0.15 12.3 0.1 1.6 1 0 0 1 1 1 0 E2 (early) protein, C terminal Peptidase_M14 PF00246.24 EKX49524.1 - 1.1e-19 71.3 0.0 1.1e-18 68.1 0.0 2.1 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 EKX49524.1 - 4.5e-06 27.0 2.0 1.3e-05 25.5 2.0 1.8 1 1 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 EKX49524.1 - 0.0042 16.2 0.0 0.0067 15.5 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family LysM PF01476.20 EKX49525.1 - 0.00083 19.4 0.1 0.12 12.5 0.0 2.1 2 0 0 2 2 2 2 LysM domain HSP20 PF00011.21 EKX49526.1 - 1.7e-08 34.5 0.0 3.7e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 Hsp20/alpha crystallin family Golgin_A5 PF09787.9 EKX49526.1 - 0.054 13.0 3.8 0.067 12.7 3.8 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 EBP50_C PF09007.11 EKX49526.1 - 0.056 14.4 0.5 0.056 14.4 0.5 1.6 2 0 0 2 2 2 0 EBP50, C-terminal ADIP PF11559.8 EKX49526.1 - 0.11 12.6 6.4 0.15 12.1 6.4 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.9 EKX49526.1 - 0.13 11.3 2.8 0.16 11.1 2.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FUSC PF04632.12 EKX49526.1 - 7 5.0 10.3 8.9 4.7 10.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family HSP20 PF00011.21 EKX49527.1 - 3.2e-14 52.9 0.0 3.6e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EKX49527.1 - 3.1e-06 26.6 0.0 9.2e-06 25.1 0.0 1.8 1 1 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 EKX49528.1 - 3.4e-08 33.5 0.0 6.9e-08 32.6 0.0 1.5 1 1 0 1 1 1 1 Hsp20/alpha crystallin family Golgin_A5 PF09787.9 EKX49528.1 - 0.097 12.1 3.9 0.13 11.8 3.9 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 EBP50_C PF09007.11 EKX49528.1 - 0.11 13.5 0.6 0.11 13.5 0.6 1.5 2 0 0 2 2 2 0 EBP50, C-terminal Atg14 PF10186.9 EKX49528.1 - 0.18 10.9 2.6 0.23 10.5 2.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 EKX49528.1 - 0.19 11.8 6.5 0.28 11.3 6.5 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding HSP20 PF00011.21 EKX49529.1 - 1.1e-13 51.2 0.0 1.5e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EKX49529.1 - 2.4e-05 23.8 0.0 6.4e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 EKX49530.1 - 8.1e-14 51.6 0.0 1.1e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EKX49530.1 - 1.7e-05 24.2 0.0 4.9e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 EKX49531.1 - 2.8e-08 33.8 0.0 5.7e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 Hsp20/alpha crystallin family EBP50_C PF09007.11 EKX49531.1 - 0.097 13.7 0.8 0.097 13.7 0.8 1.5 2 0 0 2 2 2 0 EBP50, C-terminal Atg14 PF10186.9 EKX49531.1 - 0.2 10.7 2.9 0.25 10.4 2.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 EKX49531.1 - 0.82 9.7 6.7 1.2 9.2 6.7 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding HSP20 PF00011.21 EKX49532.1 - 8.1e-14 51.6 0.0 1.1e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EKX49532.1 - 1.7e-05 24.2 0.0 4.9e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 EKX49533.1 - 3.4e-08 33.5 0.0 6.9e-08 32.6 0.0 1.5 1 1 0 1 1 1 1 Hsp20/alpha crystallin family Golgin_A5 PF09787.9 EKX49533.1 - 0.097 12.1 3.9 0.13 11.8 3.9 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 EBP50_C PF09007.11 EKX49533.1 - 0.11 13.5 0.6 0.11 13.5 0.6 1.5 2 0 0 2 2 2 0 EBP50, C-terminal Atg14 PF10186.9 EKX49533.1 - 0.18 10.9 2.6 0.23 10.5 2.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 EKX49533.1 - 0.19 11.8 6.5 0.28 11.3 6.5 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding HSP20 PF00011.21 EKX49534.1 - 1.1e-13 51.2 0.0 1.2e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EKX49534.1 - 2.6e-06 26.9 0.0 7.6e-06 25.4 0.0 1.8 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Ion_trans PF00520.31 EKX49535.1 - 3.5e-32 111.6 20.9 4.7e-32 111.2 20.9 1.1 1 0 0 1 1 1 1 Ion transport protein EF-hand_1 PF00036.32 EKX49535.1 - 3.3e-05 23.1 2.3 0.0036 16.7 0.3 3.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX49535.1 - 5.4e-05 22.8 0.2 0.011 15.6 0.1 3.1 2 0 0 2 2 2 1 EF-hand domain PKD_channel PF08016.12 EKX49535.1 - 0.00014 20.7 17.2 0.00034 19.4 17.2 1.5 1 1 0 1 1 1 1 Polycystin cation channel EF-hand_5 PF13202.6 EKX49535.1 - 0.022 14.2 0.2 0.075 12.6 0.2 1.9 1 0 0 1 1 1 0 EF hand PH PF00169.29 EKX49535.1 - 0.025 15.1 0.0 0.066 13.7 0.0 1.7 1 0 0 1 1 1 0 PH domain EF-hand_7 PF13499.6 EKX49535.1 - 0.085 13.3 0.2 1.3 9.5 0.1 2.8 2 0 0 2 2 2 0 EF-hand domain pair Di19_C PF14571.6 EKX49535.1 - 9.7 6.8 7.1 0.76 10.3 1.3 2.2 3 0 0 3 3 3 0 Stress-induced protein Di19, C-terminal DUF885 PF05960.11 EKX49536.1 - 0.0049 16.6 5.3 0.012 15.2 5.3 1.7 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Tenui_NS3 PF05310.12 EKX49536.1 - 0.13 12.4 0.3 0.29 11.3 0.0 1.7 2 0 0 2 2 2 0 Tenuivirus movement protein DUF3040 PF11239.8 EKX49536.1 - 7.4 6.9 6.1 4.9 7.5 0.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Sdh5 PF03937.16 EKX49537.1 - 8.2e-16 57.7 0.0 1.2e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase LCAT PF02450.15 EKX49538.1 - 1.1e-09 38.0 0.0 0.00059 19.1 0.0 2.2 1 1 0 2 2 2 2 Lecithin:cholesterol acyltransferase PHY PF00360.20 EKX49539.1 - 1.1e-22 80.2 0.0 2.3e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Phytochrome region PAS_9 PF13426.7 EKX49539.1 - 4.9e-09 36.4 0.0 0.0001 22.5 0.0 2.9 2 0 0 2 2 2 2 PAS domain PAS_2 PF08446.11 EKX49539.1 - 4.5e-08 33.7 0.0 3.5e-05 24.4 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 EKX49539.1 - 3.8e-06 26.9 0.0 0.057 13.4 0.0 2.8 2 0 0 2 2 2 2 PAS fold GAF PF01590.26 EKX49539.1 - 0.00022 21.9 0.0 0.00068 20.3 0.0 1.9 2 0 0 2 2 2 1 GAF domain PAS_3 PF08447.12 EKX49539.1 - 0.0012 19.1 0.0 7.9 6.8 0.0 3.8 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.10 EKX49539.1 - 0.0082 16.4 0.0 2 8.7 0.0 2.5 2 0 0 2 2 2 1 PAS fold EF-hand_1 PF00036.32 EKX49540.1 - 2.8e-15 54.6 7.3 1.5e-05 24.2 0.2 3.2 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 EKX49540.1 - 4.2e-14 51.3 5.4 0.00017 20.9 0.1 3.2 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EKX49540.1 - 6.2e-14 50.7 4.0 0.0015 18.3 0.1 3.2 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 EKX49540.1 - 1.2e-12 48.1 4.2 9.6e-07 29.2 0.7 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EKX49540.1 - 1.8e-10 40.5 1.4 0.0034 17.2 0.3 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_10 PF14788.6 EKX49540.1 - 9.3e-05 22.2 0.9 0.027 14.3 0.0 2.9 3 0 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.9 EKX49540.1 - 0.011 16.0 1.1 0.46 10.8 0.4 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 EKX49540.1 - 0.25 11.6 1.3 3 8.1 0.1 2.5 2 1 0 2 2 2 0 Dockerin type I domain LysM PF01476.20 EKX49541.1 - 8.3e-06 25.8 0.1 0.011 15.8 0.0 2.6 2 0 0 2 2 2 2 LysM domain Beta_helix PF13229.6 EKX49542.1 - 0.019 14.8 0.1 0.032 14.1 0.1 1.2 1 0 0 1 1 1 0 Right handed beta helix region TIG PF01833.24 EKX49544.1 - 4e-09 36.4 3.5 5.6e-08 32.8 1.5 2.9 2 1 0 2 2 2 1 IPT/TIG domain zf-MYND PF01753.18 EKX49545.1 - 2e-10 40.6 15.1 2e-10 40.6 15.1 2.1 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.16 EKX49545.1 - 0.0063 16.4 7.3 0.0063 16.4 7.3 1.9 2 0 0 2 2 2 1 HIT zinc finger Tudor-knot PF11717.8 EKX49546.1 - 7.6e-12 44.9 0.8 1.4e-11 44.1 0.8 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain MRG PF05712.13 EKX49546.1 - 2.9e-07 30.0 0.5 5.2e-07 29.2 0.3 1.5 1 1 0 1 1 1 1 MRG THDPS_N_2 PF14805.6 EKX49546.1 - 0.016 15.4 0.1 0.031 14.5 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal F420_oxidored PF03807.17 EKX49547.1 - 2.3e-12 47.3 1.5 3e-12 47.0 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EKX49547.1 - 1.2e-06 28.7 0.5 8.8e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EKX49547.1 - 4.2e-05 23.5 0.8 6.5e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EKX49547.1 - 0.00012 22.3 0.0 0.0002 21.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 EKX49547.1 - 0.00079 19.7 0.0 0.002 18.4 0.0 1.8 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 EKX49547.1 - 0.0052 16.2 0.1 0.015 14.7 0.1 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EKX49547.1 - 0.0093 16.0 0.2 0.047 13.7 0.1 2.1 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 EKX49547.1 - 0.012 15.3 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EKX49547.1 - 0.016 15.4 0.1 0.034 14.4 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain OCD_Mu_crystall PF02423.15 EKX49547.1 - 0.037 12.9 0.2 0.16 10.9 0.2 1.8 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family IlvN PF07991.12 EKX49547.1 - 0.049 13.2 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain PDH PF02153.17 EKX49547.1 - 0.077 12.0 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Prephenate dehydrogenase Ephrin_rec_like PF07699.13 EKX49549.1 - 4.6e-09 35.9 24.6 0.00021 21.0 3.0 3.8 2 1 1 3 3 3 3 Putative ephrin-receptor like IMCp PF12314.8 EKX49549.1 - 0.0046 17.2 9.5 0.65 10.3 5.5 2.3 2 0 0 2 2 2 2 Inner membrane complex protein TNFR_c6 PF00020.18 EKX49549.1 - 0.06 13.8 18.6 0.35 11.3 1.8 4.6 2 2 1 3 3 3 0 TNFR/NGFR cysteine-rich region LppX_LprAFG PF07161.13 EKX49549.1 - 0.072 12.9 1.5 4.3 7.1 0.1 3.2 2 1 2 4 4 4 0 LppX_LprAFG lipoprotein CNRIP1 PF15043.6 EKX49549.1 - 0.15 11.6 1.2 0.29 10.7 0.3 1.9 2 1 0 2 2 2 0 CB1 cannabinoid receptor-interacting protein 1 EGF_MSP1_1 PF12946.7 EKX49549.1 - 0.98 9.5 6.5 7.5 6.7 0.2 3.5 4 0 0 4 4 4 0 MSP1 EGF domain 1 DUF4244 PF14029.6 EKX49549.1 - 3.4 7.2 4.9 6.5 6.3 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) Elf4 PF07011.11 EKX49551.1 - 0.0054 16.6 3.5 0.024 14.5 1.2 3.3 2 0 0 2 2 2 1 Early Flowering 4 domain MCC-bdg_PDZ PF10506.9 EKX49551.1 - 0.011 15.7 3.4 0.011 15.7 3.4 11.4 13 2 1 14 14 14 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Ion_trans_2 PF07885.16 EKX49552.1 - 4e-11 42.7 0.7 1.2e-10 41.2 0.7 1.9 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EKX49552.1 - 9.3e-08 31.6 19.6 3.3e-07 29.8 19.6 1.8 1 1 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 EKX49552.1 - 2.9e-06 27.3 0.1 1.1e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain SDA1 PF05285.12 EKX49552.1 - 0.24 10.8 21.7 0.38 10.1 21.7 1.2 1 0 0 1 1 1 0 SDA1 TFIIA PF03153.13 EKX49552.1 - 0.41 10.6 9.2 0.53 10.2 9.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 EKX49552.1 - 0.67 9.2 12.0 0.87 8.9 12.0 1.2 1 0 0 1 1 1 0 BUD22 TFB6 PF17110.5 EKX49552.1 - 1.7 8.4 8.1 3.7 7.3 8.1 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Astro_capsid_p PF12226.8 EKX49552.1 - 3.5 6.7 18.8 5.6 6.0 18.8 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein ADIP PF11559.8 EKX49553.1 - 0.0044 17.1 16.7 0.0044 17.1 16.7 4.6 3 1 2 5 5 5 1 Afadin- and alpha -actinin-Binding Thioredoxin_6 PF13848.6 EKX49555.1 - 1.3e-18 67.6 1.4 4.6e-18 65.8 0.2 2.4 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin PF00085.20 EKX49555.1 - 1.6e-18 66.5 0.2 5.2e-13 48.9 0.1 2.9 3 0 0 3 3 3 2 Thioredoxin AhpC-TSA PF00578.21 EKX49555.1 - 0.0063 16.4 0.1 3 7.8 0.0 3.2 3 0 0 3 3 3 2 AhpC/TSA family PWI PF01480.17 EKX49555.1 - 0.12 12.8 0.0 2.1 8.7 0.0 2.3 2 0 0 2 2 2 0 PWI domain UDPGP PF01704.18 EKX49556.1 - 7.7e-22 77.5 0.0 1.6e-21 76.4 0.0 1.4 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase zf-RING_2 PF13639.6 EKX49557.1 - 0.016 15.5 5.9 0.016 15.5 5.9 4.2 3 2 1 4 4 4 0 Ring finger domain WD40 PF00400.32 EKX49559.1 - 2.3e-31 107.4 11.1 2.9e-10 40.5 0.1 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat CLTH PF10607.9 EKX49559.1 - 1.8e-05 24.7 0.4 5e-05 23.2 0.2 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain ANAPC4_WD40 PF12894.7 EKX49559.1 - 5.8e-05 23.3 0.4 0.047 14.0 0.0 3.4 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EKX49559.1 - 0.00012 20.9 0.3 0.41 9.2 0.1 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EKX49559.1 - 0.0014 17.5 0.8 0.04 12.7 0.5 2.6 2 1 1 3 3 3 2 Nup133 N terminal like Ge1_WD40 PF16529.5 EKX49559.1 - 0.0099 14.9 0.0 3.4 6.5 0.0 2.8 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PCO_ADO PF07847.12 EKX49560.1 - 2e-08 34.0 0.0 3.2e-08 33.3 0.0 1.4 1 1 0 1 1 1 1 PCO_ADO CENP-C_C PF11699.8 EKX49560.1 - 0.039 14.2 0.0 0.074 13.3 0.0 1.4 1 0 0 1 1 1 0 Mif2/CENP-C like CENP-Q PF13094.6 EKX49561.1 - 1.1 9.4 12.8 4.4 7.5 12.8 2.0 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Ecl1 PF12855.7 EKX49561.1 - 7.7 7.6 20.3 15 6.7 20.3 1.4 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins AAA_11 PF13086.6 EKX49562.1 - 0.0002 21.2 0.0 0.00029 20.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EKX49562.1 - 0.0056 16.2 0.0 0.016 14.7 0.0 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 EKX49562.1 - 0.011 16.1 0.1 0.036 14.4 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EKX49562.1 - 0.043 14.2 0.0 0.091 13.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EKX49562.1 - 0.047 13.2 0.2 0.099 12.2 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EKX49562.1 - 0.051 13.9 0.1 0.25 11.7 0.0 1.8 2 1 0 2 2 2 0 AAA domain Mur_ligase_C PF02875.21 EKX49562.1 - 0.085 13.1 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain GvpD PF07088.11 EKX49562.1 - 0.1 11.2 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_22 PF13401.6 EKX49562.1 - 0.12 12.6 0.1 0.56 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EKX49562.1 - 0.16 11.7 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ZapB PF06005.12 EKX49563.1 - 1.2e-05 25.6 14.9 0.13 12.7 1.4 3.3 3 1 0 3 3 3 2 Cell division protein ZapB DUF948 PF06103.11 EKX49563.1 - 2.2e-05 24.6 10.6 0.00094 19.4 2.8 3.0 1 1 2 3 3 3 2 Bacterial protein of unknown function (DUF948) Tropomyosin_1 PF12718.7 EKX49563.1 - 4e-05 23.8 21.5 0.0064 16.7 9.5 2.6 1 1 1 2 2 2 2 Tropomyosin like Spc7 PF08317.11 EKX49563.1 - 8.3e-05 21.6 2.6 8.3e-05 21.6 2.6 2.3 1 1 1 2 2 2 1 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 EKX49563.1 - 0.00013 22.0 0.1 0.002 18.2 0.0 2.3 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2312 PF10073.9 EKX49563.1 - 0.0002 20.9 5.8 0.0035 17.0 0.6 4.0 3 1 1 4 4 3 2 Uncharacterized protein conserved in bacteria (DUF2312) Laminin_II PF06009.12 EKX49563.1 - 0.00062 19.8 11.1 0.025 14.6 2.4 2.3 1 1 1 2 2 2 2 Laminin Domain II Sec34 PF04136.15 EKX49563.1 - 0.0011 18.8 0.3 0.11 12.4 0.0 2.6 1 1 2 3 3 3 1 Sec34-like family COG2 PF06148.11 EKX49563.1 - 0.0012 18.9 16.1 0.015 15.4 1.6 3.6 1 1 3 4 4 4 3 COG (conserved oligomeric Golgi) complex component, COG2 Laminin_I PF06008.14 EKX49563.1 - 0.0012 18.6 4.1 0.0012 18.6 4.1 2.6 1 1 0 1 1 1 1 Laminin Domain I Fib_alpha PF08702.10 EKX49563.1 - 0.0039 17.4 1.4 0.0039 17.4 1.4 1.9 1 1 1 2 2 2 1 Fibrinogen alpha/beta chain family EzrA PF06160.12 EKX49563.1 - 0.0039 15.4 1.1 0.0039 15.4 1.1 2.3 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA DHR10 PF18595.1 EKX49563.1 - 0.008 16.2 21.4 0.049 13.7 10.8 2.3 1 1 1 2 2 2 2 Designed helical repeat protein 10 domain TMPIT PF07851.13 EKX49563.1 - 0.0087 15.3 6.8 0.057 12.7 1.1 2.1 1 1 1 2 2 2 2 TMPIT-like protein MCPsignal PF00015.21 EKX49563.1 - 0.0089 15.9 16.2 0.047 13.5 3.9 2.1 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Tropomyosin PF00261.20 EKX49563.1 - 0.012 15.0 21.3 0.21 10.9 4.0 2.3 1 1 1 2 2 2 0 Tropomyosin ATG16 PF08614.11 EKX49563.1 - 0.013 15.8 15.1 0.02 15.1 1.0 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 EKX49563.1 - 0.018 15.5 19.1 0.11 12.9 1.4 4.0 2 1 4 6 6 5 0 Flagella accessory protein C (FlaC) HsbA PF12296.8 EKX49563.1 - 0.023 15.1 2.2 0.3 11.5 0.7 2.3 1 1 0 1 1 1 0 Hydrophobic surface binding protein A BLOC1_2 PF10046.9 EKX49563.1 - 0.035 14.4 10.1 0.065 13.5 0.2 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF5082 PF16888.5 EKX49563.1 - 0.039 14.2 14.8 0.36 11.1 1.1 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) DUF4140 PF13600.6 EKX49563.1 - 0.039 14.4 16.0 1.1e+04 -3.0 16.0 3.8 1 1 0 1 1 0 0 N-terminal domain of unknown function (DUF4140) Rh5 PF18515.1 EKX49563.1 - 0.048 12.9 1.8 0.1 11.9 1.7 1.6 1 1 0 1 1 1 0 Rh5 coiled-coil domain AAA_13 PF13166.6 EKX49563.1 - 0.051 12.2 20.1 0.095 11.3 4.4 2.8 1 1 0 2 2 2 0 AAA domain DUF3584 PF12128.8 EKX49563.1 - 0.072 10.6 14.7 0.086 10.4 14.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NPV_P10 PF05531.12 EKX49563.1 - 0.11 12.9 11.4 2.2e+02 2.4 11.4 3.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein APG17 PF04108.12 EKX49563.1 - 0.14 11.3 9.2 0.012 14.8 3.0 2.1 1 1 0 2 2 2 0 Autophagy protein Apg17 Prominin PF05478.11 EKX49563.1 - 0.16 9.9 5.6 0.054 11.5 1.8 2.0 1 1 0 1 1 1 0 Prominin Med9 PF07544.13 EKX49563.1 - 0.19 11.9 16.4 0.47 10.6 0.1 4.8 1 1 3 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Syntaxin_2 PF14523.6 EKX49563.1 - 0.22 11.9 6.4 45 4.5 6.4 3.3 1 1 0 1 1 1 0 Syntaxin-like protein DUF812 PF05667.11 EKX49563.1 - 0.28 10.0 18.4 1.1 8.0 18.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DivIC PF04977.15 EKX49563.1 - 0.29 10.9 20.9 1.2 8.9 0.1 4.2 1 1 4 5 5 5 0 Septum formation initiator Fez1 PF06818.15 EKX49563.1 - 0.33 11.4 15.5 3.7 8.0 15.5 2.2 1 1 0 1 1 1 0 Fez1 APG6_N PF17675.1 EKX49563.1 - 0.34 11.4 20.3 1.8e+04 -4.0 20.3 3.2 1 1 0 1 1 0 0 Apg6 coiled-coil region DUF3209 PF11483.8 EKX49563.1 - 0.37 11.3 5.4 1.5 9.3 1.6 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3209) Cast PF10174.9 EKX49563.1 - 0.46 8.6 20.0 0.55 8.4 20.0 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF1664 PF07889.12 EKX49563.1 - 0.5 10.4 18.3 0.086 12.9 4.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF2203 PF09969.9 EKX49563.1 - 0.57 10.9 18.0 0.46 11.2 3.4 3.1 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF4407 PF14362.6 EKX49563.1 - 1 8.7 14.0 12 5.1 14.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 EKX49563.1 - 1 10.0 11.8 25 5.6 0.4 3.5 1 1 1 2 2 2 0 Initiation control protein YabA DUF4200 PF13863.6 EKX49563.1 - 1.3 9.4 23.9 0.63 10.5 2.5 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) zf-C4H2 PF10146.9 EKX49563.1 - 1.4 9.2 14.1 0.14 12.4 4.8 2.4 1 1 1 2 2 2 0 Zinc finger-containing protein Kre28 PF17097.5 EKX49563.1 - 1.4 7.7 14.1 0.23 10.3 7.0 1.9 1 1 1 2 2 2 0 Spindle pole body component DUF1149 PF06619.11 EKX49563.1 - 2.3 8.5 10.6 10 6.4 2.8 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1149) DUF16 PF01519.16 EKX49563.1 - 2.9 8.4 21.2 0.72 10.4 6.2 3.1 1 1 2 3 3 3 0 Protein of unknown function DUF16 FAM76 PF16046.5 EKX49563.1 - 2.9 7.2 12.7 4.1 6.7 12.7 1.3 1 0 0 1 1 1 0 FAM76 protein TMF_DNA_bd PF12329.8 EKX49563.1 - 3.1 7.9 23.1 6 6.9 0.3 3.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.9 EKX49563.1 - 5.1 6.1 14.3 2.7e+02 0.4 14.3 2.1 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3552 PF12072.8 EKX49563.1 - 5.3 6.4 25.1 2.6 7.4 13.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) ISG65-75 PF11727.8 EKX49563.1 - 5.6 6.1 15.6 3.9 6.6 4.3 2.1 1 1 1 2 2 2 0 Invariant surface glycoprotein LMBR1 PF04791.16 EKX49563.1 - 7.6 5.3 5.1 11 4.8 5.1 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Cauli_AT PF03233.13 EKX49563.1 - 9.3 6.1 18.8 1.9 8.4 4.1 3.1 1 1 2 3 3 3 0 Aphid transmission protein Transketolase_N PF00456.21 EKX49564.1 - 5.1e-107 357.7 0.5 6.5e-107 357.4 0.5 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EKX49564.1 - 3.1e-39 134.5 0.0 5.1e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EKX49564.1 - 2.5e-08 33.9 0.0 5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EKX49564.1 - 5.2e-08 32.4 0.1 1.7e-05 24.2 0.0 2.5 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 EKX49564.1 - 8.3e-07 28.2 0.2 1.5e-06 27.4 0.2 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component RapA_C PF12137.8 EKX49565.1 - 0.13 11.2 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal Peptidase_C48 PF02902.19 EKX49566.1 - 3e-26 92.6 0.1 2e-24 86.6 0.1 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SAM_decarbox PF01536.16 EKX49567.1 - 5.9e-90 301.8 0.0 7.3e-90 301.5 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase SPO22 PF08631.10 EKX49568.1 - 0.0011 18.5 0.2 0.0018 17.8 0.2 1.4 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like NosD PF05048.13 EKX49569.1 - 1.2e-23 83.6 3.2 6.8e-15 55.0 5.2 2.0 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.6 EKX49569.1 - 6.1e-21 74.9 12.8 3.2e-12 46.6 10.6 2.1 1 1 1 2 2 2 2 Right handed beta helix region DUF1565 PF07602.11 EKX49569.1 - 9.3e-05 21.9 2.5 0.059 12.7 2.6 2.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1565) Pectinesterase PF01095.19 EKX49569.1 - 0.0074 15.0 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 Pectinesterase DUF5570 PF17731.1 EKX49569.1 - 0.014 15.5 3.7 0.054 13.6 3.7 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5570) CRAL_TRIO_N PF03765.15 EKX49569.1 - 0.043 14.0 0.4 1 9.6 0.1 2.4 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain ABC_tran PF00005.27 EKX49572.1 - 3.1e-52 176.7 0.1 2.2e-29 102.7 0.2 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EKX49572.1 - 2.9e-33 115.7 16.3 2.6e-21 76.5 6.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EKX49572.1 - 1.5e-11 44.1 3.4 0.0016 18.0 0.0 3.9 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EKX49572.1 - 0.00021 21.4 0.2 0.05 13.7 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 EKX49572.1 - 0.001 18.7 2.7 0.34 10.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF5408 PF17402.2 EKX49572.1 - 0.0059 16.4 1.2 0.0059 16.4 1.2 1.9 2 0 0 2 2 1 1 Family of unknown function (DUF5408) AAA_16 PF13191.6 EKX49572.1 - 0.0078 16.6 2.2 3.1 8.2 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EKX49572.1 - 0.0089 16.3 1.4 0.21 11.9 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EKX49572.1 - 0.016 14.8 0.1 0.86 9.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EKX49572.1 - 0.033 13.9 0.1 0.19 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EKX49572.1 - 0.09 12.4 1.2 2.3 7.8 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EKX49572.1 - 0.09 12.7 1.3 1.3 8.9 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase DUF87 PF01935.17 EKX49572.1 - 0.095 12.8 3.9 0.17 12.0 0.2 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain SpoIIIAH PF12685.7 EKX49572.1 - 0.11 12.3 1.0 5.1 6.9 0.1 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein AAA_7 PF12775.7 EKX49572.1 - 0.12 11.8 0.4 0.94 9.0 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 EKX49572.1 - 0.15 11.0 1.6 4.9 6.0 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF815 PF05673.13 EKX49572.1 - 0.22 10.6 0.7 0.58 9.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_21 PF13304.6 EKX49572.1 - 0.23 11.3 19.3 0.56 10.0 0.2 5.1 5 1 1 6 6 5 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EKX49572.1 - 0.57 10.7 6.5 5.4 7.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 EKX49572.1 - 0.63 9.7 6.3 32 4.2 3.3 3.2 2 1 0 2 2 2 0 AAA domain Mpp10 PF04006.12 EKX49572.1 - 2.9 6.2 30.1 0.03 12.8 2.3 2.1 2 0 0 2 2 2 0 Mpp10 protein Dynamin_N PF00350.23 EKX49572.1 - 7.1 6.7 7.3 8.3 6.4 0.1 2.8 3 0 0 3 3 3 0 Dynamin family UQ_con PF00179.26 EKX49573.1 - 3.2e-16 59.3 0.0 4.4e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EKX49573.1 - 0.0023 17.6 0.0 0.0028 17.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EKX49573.1 - 0.19 12.0 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 RWD domain DEAD PF00270.29 EKX49574.1 - 3e-49 167.2 0.0 4.4e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase SPRY PF00622.28 EKX49574.1 - 9.5e-21 74.1 0.0 1.7e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 SPRY domain Helicase_C PF00271.31 EKX49574.1 - 9.6e-21 74.2 0.0 1.9e-20 73.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.6 EKX49574.1 - 0.00052 19.4 0.0 0.00094 18.6 0.0 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit NUDIX PF00293.28 EKX49575.1 - 2.6e-08 34.0 0.0 3.5e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain AAA_11 PF13086.6 EKX49577.1 - 0.00012 21.9 0.0 0.00019 21.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EKX49577.1 - 0.0016 18.0 0.1 0.0037 16.8 0.0 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 EKX49577.1 - 0.0017 18.8 0.1 0.0038 17.6 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EKX49577.1 - 0.007 16.0 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EKX49577.1 - 0.024 15.1 0.0 0.05 14.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EKX49577.1 - 0.064 13.6 0.0 0.15 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EKX49577.1 - 0.079 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EKX49577.1 - 0.12 12.9 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain GvpD PF07088.11 EKX49577.1 - 0.14 10.7 0.0 0.25 9.9 0.0 1.3 1 0 0 1 1 1 0 GvpD gas vesicle protein NACHT PF05729.12 EKX49577.1 - 0.15 12.0 0.1 0.37 10.7 0.1 1.7 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 EKX49577.1 - 0.17 12.2 0.0 0.58 10.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain Enolase_N PF03952.16 EKX49578.1 - 1.2e-35 122.5 0.0 1.3e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 Enolase, N-terminal domain Gag_p17 PF00540.18 EKX49578.1 - 0.18 11.8 0.0 0.22 11.5 0.0 1.1 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) ETX_MTX2 PF03318.13 EKX49578.1 - 0.18 11.6 0.1 1.8 8.3 0.1 1.9 1 1 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 AAA_11 PF13086.6 EKX49580.1 - 0.00015 21.7 0.0 0.00023 21.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EKX49580.1 - 0.0012 18.4 0.1 0.003 17.1 0.0 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 EKX49580.1 - 0.0013 19.1 0.1 0.0038 17.6 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EKX49580.1 - 0.0086 15.7 0.1 0.023 14.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EKX49580.1 - 0.021 15.2 0.0 0.044 14.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EKX49580.1 - 0.067 13.5 0.0 0.16 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EKX49580.1 - 0.11 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EKX49580.1 - 0.12 13.0 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain GvpD PF07088.11 EKX49580.1 - 0.15 10.7 0.0 0.27 9.8 0.0 1.3 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_22 PF13401.6 EKX49580.1 - 0.15 12.3 0.1 0.58 10.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EKX49580.1 - 0.15 12.0 0.1 0.37 10.7 0.1 1.7 1 0 0 1 1 1 0 NACHT domain Enolase_N PF03952.16 EKX49581.1 - 3.9e-32 111.2 0.1 4.4e-32 111.0 0.1 1.0 1 0 0 1 1 1 1 Enolase, N-terminal domain ETX_MTX2 PF03318.13 EKX49581.1 - 0.1 12.4 0.1 4.4 7.0 0.0 2.0 1 1 1 2 2 2 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 AAA_11 PF13086.6 EKX49584.1 - 0.00029 20.7 0.0 0.00029 20.7 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 EKX49584.1 - 0.0017 18.8 0.1 0.0045 17.4 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 EKX49584.1 - 0.0018 17.8 0.0 0.0047 16.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF948 PF06103.11 EKX49584.1 - 0.0084 16.3 3.9 0.018 15.2 3.9 1.6 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) AAA_25 PF13481.6 EKX49584.1 - 0.0087 15.6 0.1 0.035 13.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EKX49584.1 - 0.011 16.2 0.0 0.041 14.3 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EKX49584.1 - 0.027 14.8 0.6 0.25 11.6 0.0 2.7 3 1 0 3 3 3 0 AAA domain T3SSipB PF16535.5 EKX49584.1 - 0.35 11.3 6.1 0.61 10.6 5.4 1.6 1 1 0 1 1 1 0 Type III cell invasion protein SipB Nmad5 PF18757.1 EKX49584.1 - 0.36 11.0 4.7 0.14 12.3 0.7 2.1 2 0 0 2 2 2 0 Nucleotide modification associated domain 5 Kre28 PF17097.5 EKX49584.1 - 1 8.2 8.8 1.7 7.6 8.8 1.3 1 0 0 1 1 1 0 Spindle pole body component DUF4686 PF15742.5 EKX49584.1 - 1.1 8.3 21.0 0.23 10.6 17.8 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4686) Fez1 PF06818.15 EKX49584.1 - 2.4 8.5 15.0 29 5.0 15.1 2.2 1 1 1 2 2 2 0 Fez1 DUF2312 PF10073.9 EKX49584.1 - 5.2 6.8 15.6 1.1 9.0 0.2 4.2 2 2 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) PARP PF00644.20 EKX49585.1 - 3.5e-14 52.8 1.4 1e-12 48.1 1.4 2.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Enolase_C PF00113.22 EKX49586.1 - 8.7e-34 117.1 0.2 1.1e-33 116.8 0.2 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EKX49586.1 - 5.3e-25 88.1 0.0 8.6e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain TCR_zetazeta PF11628.8 EKX49587.1 - 0.34 10.6 0.0 0.34 10.6 0.0 2.4 3 0 0 3 3 3 0 T-cell surface glycoprotein CD3 zeta chain RNA_pol_Rpb2_6 PF00562.28 EKX49588.1 - 2.8e-126 421.7 0.2 4e-126 421.2 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EKX49588.1 - 2.2e-50 171.0 0.2 3.5e-50 170.3 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EKX49588.1 - 4.9e-40 137.2 0.1 1e-39 136.2 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EKX49588.1 - 3.6e-29 101.0 0.3 1.5e-28 99.0 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 EKX49588.1 - 4.1e-23 81.3 0.0 8.4e-23 80.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 EKX49588.1 - 9.9e-20 70.6 0.1 4.2e-19 68.6 0.1 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 EKX49588.1 - 2.4e-14 53.6 0.8 7.5e-14 52.0 0.8 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DOCK-C2 PF14429.6 EKX49591.1 - 0.055 13.3 0.7 0.26 11.1 0.2 2.0 1 1 1 2 2 2 0 C2 domain in Dock180 and Zizimin proteins Polysacc_deac_1 PF01522.21 EKX49593.1 - 4.8e-10 39.4 0.0 1e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase CarboxypepD_reg PF13620.6 EKX49594.1 - 0.00013 22.1 0.2 0.0028 17.9 0.2 2.9 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain ABC_tran PF00005.27 EKX49595.1 - 1.3e-42 145.6 1.5 2.7e-22 79.7 0.0 2.9 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EKX49595.1 - 7e-18 65.5 2.6 3.9e-07 30.2 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EKX49595.1 - 5.7e-13 48.8 0.3 0.0012 18.4 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EKX49595.1 - 8.4e-07 29.0 0.1 0.05 13.5 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 EKX49595.1 - 1.9e-06 27.9 0.0 0.069 13.1 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 EKX49595.1 - 3.6e-06 27.3 0.0 0.15 12.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 EKX49595.1 - 8.7e-06 26.4 0.9 0.11 13.0 0.0 2.6 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EKX49595.1 - 1.3e-05 25.2 0.1 0.11 12.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EKX49595.1 - 3.5e-05 23.5 2.2 0.14 12.0 0.1 2.7 3 0 0 3 3 2 2 P-loop containing region of AAA domain NB-ARC PF00931.22 EKX49595.1 - 3.7e-05 23.0 0.1 0.097 11.8 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_24 PF13479.6 EKX49595.1 - 5.2e-05 23.0 1.3 0.94 9.2 0.0 3.7 4 0 0 4 4 4 2 AAA domain Roc PF08477.13 EKX49595.1 - 0.00016 21.9 0.0 0.37 11.0 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 EKX49595.1 - 0.00037 20.3 1.4 2 8.1 0.3 3.5 3 1 0 3 3 3 2 AAA domain MobB PF03205.14 EKX49595.1 - 0.00048 20.0 0.1 1.5 8.8 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.6 EKX49595.1 - 0.00063 20.2 0.0 1.1 9.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 EKX49595.1 - 0.00092 19.5 0.0 1.6 8.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EKX49595.1 - 0.00092 19.8 0.0 2.4 8.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain PduV-EutP PF10662.9 EKX49595.1 - 0.0012 18.6 0.5 0.79 9.5 0.1 2.7 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 EKX49595.1 - 0.0019 18.3 0.6 0.4 10.7 0.1 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain TsaE PF02367.17 EKX49595.1 - 0.0022 18.0 0.9 0.24 11.4 0.1 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SbcCD_C PF13558.6 EKX49595.1 - 0.0022 18.2 0.1 1.4 9.2 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 EKX49595.1 - 0.0027 18.1 0.0 2.9 8.3 0.0 2.4 2 0 0 2 2 2 1 RNA helicase MeaB PF03308.16 EKX49595.1 - 0.0036 16.3 0.7 0.53 9.2 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 EKX49595.1 - 0.0036 17.2 0.8 2.5 8.0 0.1 3.0 3 0 0 3 3 2 1 NTPase AAA_15 PF13175.6 EKX49595.1 - 0.0037 17.0 0.0 1.2 8.8 0.0 2.6 3 0 0 3 3 2 1 AAA ATPase domain AAA PF00004.29 EKX49595.1 - 0.004 17.6 0.0 4.1 7.8 0.0 2.7 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Arf PF00025.21 EKX49595.1 - 0.0042 16.6 0.2 0.096 12.1 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_14 PF13173.6 EKX49595.1 - 0.0062 16.6 0.0 1.9 8.5 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.14 EKX49595.1 - 0.0063 16.5 0.1 5.7 6.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EKX49595.1 - 0.0064 16.1 0.0 4.6 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 EKX49595.1 - 0.0067 16.1 0.2 0.044 13.4 0.1 2.1 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF3584 PF12128.8 EKX49595.1 - 0.01 13.4 3.8 0.17 9.3 0.3 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3584) SRP54 PF00448.22 EKX49595.1 - 0.011 15.4 1.4 2.7 7.6 0.1 2.7 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain cobW PF02492.19 EKX49595.1 - 0.012 15.2 0.2 5.7 6.5 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EKX49595.1 - 0.014 15.6 0.0 7.8 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EKX49595.1 - 0.015 15.1 0.3 3.3 7.4 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_13 PF13166.6 EKX49595.1 - 0.046 12.4 0.0 1.2 7.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EKX49595.1 - 0.057 12.9 0.2 8.2 5.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DLIC PF05783.11 EKX49595.1 - 0.059 12.2 0.5 6.8 5.4 0.1 2.2 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) ATPase_2 PF01637.18 EKX49595.1 - 0.07 13.0 0.0 10 5.9 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Chromo PF00385.24 EKX49595.1 - 0.071 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain ATPase PF06745.13 EKX49595.1 - 0.076 12.3 0.3 0.4 10.0 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_17 PF13207.6 EKX49595.1 - 0.077 13.4 0.0 14 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 EKX49595.1 - 0.11 11.8 0.1 10 5.3 0.0 2.3 2 0 0 2 2 2 0 Septin FeoB_N PF02421.18 EKX49595.1 - 0.14 11.6 0.1 20 4.7 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Ploopntkinase3 PF18751.1 EKX49595.1 - 0.15 12.0 0.0 12 5.8 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 G-alpha PF00503.20 EKX49595.1 - 0.15 11.2 0.0 1 8.4 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit Ras PF00071.22 EKX49595.1 - 0.16 11.6 0.8 5.2 6.6 0.0 2.6 3 0 0 3 3 2 0 Ras family Zeta_toxin PF06414.12 EKX49595.1 - 0.16 11.2 0.0 12 5.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 EKX49595.1 - 0.33 11.3 1.4 18 5.6 0.0 2.6 2 2 0 2 2 2 0 AAA domain Methyltransf_25 PF13649.6 EKX49596.1 - 2.4e-17 63.4 0.1 1.9e-16 60.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX49596.1 - 1.6e-14 54.3 0.0 3e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX49596.1 - 2.9e-14 53.6 0.0 4.5e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX49596.1 - 4.3e-14 52.7 0.0 7.3e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX49596.1 - 1.1e-12 48.0 0.1 1.6e-12 47.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EKX49596.1 - 5.9e-10 38.9 0.0 8e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EKX49596.1 - 2.3e-08 33.7 0.0 5.4e-08 32.5 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.12 EKX49596.1 - 7.1e-06 25.7 0.0 9.9e-06 25.2 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.7 EKX49596.1 - 0.00075 19.5 0.0 0.075 13.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.14 EKX49596.1 - 0.00095 18.6 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB DREV PF05219.12 EKX49596.1 - 0.0032 16.6 0.0 0.011 14.9 0.0 1.7 1 1 0 1 1 1 1 DREV methyltransferase MTS PF05175.14 EKX49596.1 - 0.0085 15.7 0.0 0.017 14.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 EKX49596.1 - 0.016 14.8 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) DUF2502 PF10697.9 EKX49596.1 - 0.061 13.7 0.5 0.099 13.0 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2502) UPF0020 PF01170.18 EKX49596.1 - 0.16 11.6 0.0 0.51 10.0 0.0 1.7 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Glycos_transf_1 PF00534.20 EKX49597.1 - 6.4e-13 48.6 0.0 8e-13 48.3 0.0 1.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EKX49597.1 - 4.2e-11 43.4 0.0 5.5e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EKX49597.1 - 3.8e-07 30.4 0.0 1.2e-06 28.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glycogen_syn PF05693.13 EKX49597.1 - 0.047 12.2 0.0 0.057 12.0 0.0 1.0 1 0 0 1 1 1 0 Glycogen synthase Creatinase_N_2 PF16189.5 EKX49598.1 - 1.9e-49 167.9 0.0 5e-46 156.7 0.0 3.0 3 0 0 3 3 3 2 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 EKX49598.1 - 1.3e-25 90.3 0.0 2.3e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 EKX49598.1 - 4.8e-19 69.3 0.0 5.3e-14 53.0 0.0 2.3 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain DUF5420 PF17457.2 EKX49598.1 - 0.17 11.7 0.0 13 5.6 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5420) Macoilin PF09726.9 EKX49599.1 - 0.12 10.9 8.7 0.15 10.6 8.7 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 EKX49599.1 - 0.51 9.1 6.0 0.6 8.9 6.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain AF-4 PF05110.13 EKX49599.1 - 2.2 6.2 17.9 2.5 6.1 17.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF155 PF02582.14 EKX49600.1 - 7.1e-25 88.1 0.0 1.3e-24 87.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 WD40 PF00400.32 EKX49601.1 - 4e-26 90.7 16.3 2.2e-06 28.3 0.0 8.9 10 0 0 10 10 10 5 WD domain, G-beta repeat C2 PF00168.30 EKX49601.1 - 4.8e-10 39.7 0.4 9.3e-06 25.9 0.1 2.6 2 0 0 2 2 2 2 C2 domain BBS2_Mid PF14783.6 EKX49601.1 - 0.029 14.4 0.1 35 4.5 0.0 4.4 5 0 0 5 5 5 0 Ciliary BBSome complex subunit 2, middle region TSC22 PF01166.18 EKX49603.1 - 0.026 14.8 0.4 0.11 12.9 0.4 2.1 1 0 0 1 1 1 0 TSC-22/dip/bun family Presenilin PF01080.17 EKX49603.1 - 0.45 9.2 3.0 0.81 8.4 3.0 1.3 1 0 0 1 1 1 0 Presenilin SUIM_assoc PF16619.5 EKX49603.1 - 1.6 8.9 12.3 0.048 13.7 2.7 3.3 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 EKX49603.1 - 2.9 7.4 14.0 6.1 6.4 14.0 1.4 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 EKX49603.1 - 6.7 7.7 6.8 32 5.6 6.8 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) EF-hand_1 PF00036.32 EKX49604.1 - 1.1e-41 137.3 12.9 3.5e-10 38.7 1.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EKX49604.1 - 7.5e-36 122.4 3.1 3.5e-18 65.8 1.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EKX49604.1 - 1.5e-31 108.0 11.3 2.2e-15 56.2 0.8 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EKX49604.1 - 3.9e-30 101.2 7.1 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EKX49604.1 - 3.3e-27 92.7 10.0 2.1e-06 27.0 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EKX49604.1 - 7.5e-16 58.2 0.2 3.3e-09 37.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EKX49604.1 - 6.5e-10 38.9 0.6 9.7e-05 22.3 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EKX49604.1 - 4.1e-08 33.5 0.3 0.004 17.4 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 EKX49604.1 - 1.8e-06 28.8 0.0 0.00047 21.0 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 EKX49604.1 - 1.8e-05 24.7 0.3 0.042 13.9 0.0 3.1 3 1 0 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 EKX49604.1 - 5.4e-05 23.2 1.1 0.00026 21.0 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 EKX49604.1 - 0.0002 21.5 3.7 0.06 13.5 0.3 2.9 1 1 1 2 2 2 2 Dockerin type I domain DUF3349 PF11829.8 EKX49604.1 - 0.0011 19.7 0.5 1.2 10.0 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) TerB PF05099.13 EKX49604.1 - 0.0014 18.6 0.4 0.49 10.3 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.16 EKX49604.1 - 0.0022 18.3 0.1 1.4 9.3 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb4 Caleosin PF05042.13 EKX49604.1 - 0.0024 17.8 0.8 0.44 10.5 0.0 3.3 1 1 3 4 4 4 1 Caleosin related protein DUF1103 PF06513.11 EKX49604.1 - 0.0042 16.7 1.8 0.0048 16.5 1.8 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) SurA_N_2 PF13623.6 EKX49604.1 - 0.016 15.0 0.5 1 9.2 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain MotA_activ PF09114.10 EKX49604.1 - 0.016 15.3 0.4 0.25 11.5 0.1 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain Poly_export PF02563.16 EKX49604.1 - 0.02 15.1 0.1 3.7 7.8 0.0 3.1 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 EKX49604.1 - 0.021 15.3 0.0 6.9 7.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4497) DUF853 PF05872.12 EKX49604.1 - 0.029 13.0 0.1 0.79 8.2 0.0 2.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF853) EF-hand_14 PF17959.1 EKX49604.1 - 0.044 14.1 0.1 9.3 6.7 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain Fe_hyd_lg_C PF02906.14 EKX49604.1 - 0.053 13.2 0.6 0.19 11.4 0.6 1.8 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain dCache_2 PF08269.11 EKX49604.1 - 0.064 12.4 0.1 5.2 6.1 0.0 2.2 1 1 1 2 2 2 0 Cache domain DUF5580 PF17743.1 EKX49604.1 - 0.098 11.2 0.0 0.098 11.2 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) SapB_1 PF05184.15 EKX49604.1 - 0.22 11.6 2.7 27 4.9 0.0 3.5 4 0 0 4 4 4 0 Saposin-like type B, region 1 Syja_N PF02383.18 EKX49606.1 - 8.1e-63 212.7 0.0 1.2e-62 212.1 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain IFRD PF05004.13 EKX49608.1 - 2.2e-37 128.8 4.7 3.3e-37 128.2 4.7 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) IFRD_C PF04836.12 EKX49608.1 - 0.0096 16.5 0.2 0.023 15.3 0.2 1.7 1 0 0 1 1 1 1 Interferon-related protein conserved region DDE_Tnp_1_7 PF13843.6 EKX49610.1 - 7e-20 71.6 0.0 1.3e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 Transposase IS4 DUF4116 PF13475.6 EKX49611.1 - 2.4e-37 126.4 0.2 4.4e-10 39.1 0.0 3.9 1 1 4 5 5 5 5 Domain of unknown function (DUF4116) DNA_alkylation PF08713.11 EKX49611.1 - 0.021 14.5 0.1 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 DNA alkylation repair enzyme Spc24 PF08286.11 EKX49612.1 - 0.39 11.0 4.0 4.4 7.6 1.5 2.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 HECT PF00632.25 EKX49613.1 - 1e-93 314.2 0.0 1.2e-93 314.0 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) FNIP_C PF14638.6 EKX49614.1 - 0.044 13.4 0.1 0.068 12.8 0.1 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein C-terminus baeRF_family10 PF18854.1 EKX49614.1 - 0.065 13.5 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 WD40 PF00400.32 EKX49615.1 - 9.6e-24 83.2 13.2 7.8e-11 42.4 0.6 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.8 EKX49615.1 - 5.1e-05 22.1 4.3 0.061 12.0 0.1 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EKX49615.1 - 0.0013 17.6 0.9 0.025 13.3 0.3 2.0 1 1 1 2 2 2 1 Nup133 N terminal like WD40_like PF17005.5 EKX49615.1 - 0.0041 16.5 0.0 0.11 11.8 0.0 2.2 1 1 1 2 2 2 1 WD40-like domain CdiA_C PF18451.1 EKX49615.1 - 0.0092 16.2 0.1 0.086 13.1 0.0 2.4 2 1 0 2 2 2 1 Contact-dependent growth inhibition CdiA C-terminal domain CIDE-N PF02017.15 EKX49615.1 - 0.043 13.8 1.0 2.5 8.2 0.1 2.8 2 1 1 3 3 3 0 CIDE-N domain PQQ_3 PF13570.6 EKX49615.1 - 0.044 14.3 0.0 5.8 7.5 0.0 2.8 3 0 0 3 3 3 0 PQQ-like domain ART PF01129.18 EKX49616.1 - 1.2e-09 37.8 0.0 1.6e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase ADPrib_exo_Tox PF03496.14 EKX49616.1 - 8.6e-06 25.2 0.0 0.008 15.5 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosyltransferase exoenzyme TetR_N PF00440.23 EKX49616.1 - 0.094 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Glyco_transf_41 PF13844.6 EKX49617.1 - 6.8e-58 196.2 0.0 2e-32 112.3 0.2 2.6 1 1 0 2 2 2 2 Glycosyl transferase family 41 RNase_H2-Ydr279 PF09468.10 EKX49617.1 - 0.15 12.3 0.0 0.38 10.9 0.0 1.7 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain His_Phos_1 PF00300.22 EKX49620.1 - 2.9e-06 27.1 0.0 0.00014 21.6 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) LRR_6 PF13516.6 EKX49622.1 - 6.5e-35 116.2 23.5 1.9e-06 27.5 0.2 11.7 12 0 0 12 12 12 8 Leucine Rich repeat LRR_4 PF12799.7 EKX49622.1 - 9.4e-08 32.3 11.0 0.11 13.0 0.3 7.0 4 2 4 8 8 8 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX49622.1 - 5.8e-07 29.2 12.0 0.9 10.3 0.1 8.7 8 2 0 8 8 8 2 Leucine Rich Repeat LRR_8 PF13855.6 EKX49622.1 - 0.14 11.9 21.3 7.2 6.5 2.0 7.8 5 3 1 6 6 6 0 Leucine rich repeat cNMP_binding PF00027.29 EKX49623.1 - 6.2e-16 58.3 0.0 2.9e-12 46.5 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain PTEN_C2 PF10409.9 EKX49623.1 - 2.1e-05 24.3 0.2 4.6e-05 23.2 0.2 1.6 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 EKX49623.1 - 0.0003 20.6 0.0 0.00077 19.3 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EKX49623.1 - 0.0034 17.4 0.0 0.0061 16.6 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EKX49623.1 - 0.028 14.0 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase MAPEG PF01124.18 EKX49624.1 - 1.5e-14 54.0 0.7 2.7e-14 53.2 0.7 1.4 1 1 0 1 1 1 1 MAPEG family Adaptin_N PF01602.20 EKX49625.1 - 4.5e-102 342.3 12.3 6.8e-102 341.7 12.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 EKX49625.1 - 6.3e-56 187.9 0.1 1.7e-55 186.4 0.1 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 EKX49625.1 - 8.7e-53 178.0 0.1 2.3e-52 176.6 0.1 1.8 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 EKX49625.1 - 6.3e-09 36.1 0.2 0.0012 19.2 0.0 3.9 2 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.7 EKX49625.1 - 5.7e-07 29.7 8.5 1.1e-05 25.6 0.0 3.7 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Coatomer_g_Cpla PF16381.5 EKX49625.1 - 0.00013 22.0 0.0 0.0006 19.9 0.0 2.2 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 EKX49625.1 - 0.0019 18.3 3.8 14 6.3 0.0 5.5 5 1 0 6 6 6 1 HEAT repeat DUF5578 PF17741.1 EKX49625.1 - 0.0028 17.1 5.3 0.036 13.5 1.6 2.7 1 1 1 2 2 2 1 Family of unknown function (DUF5578) HEAT_EZ PF13513.6 EKX49625.1 - 0.0083 16.6 0.1 9.8 6.8 0.0 4.7 3 1 2 5 5 5 1 HEAT-like repeat La PF05383.17 EKX49627.1 - 3.1e-22 78.4 0.0 4e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 La domain Metallophos PF00149.28 EKX49630.1 - 9.3e-29 101.4 0.1 1.5e-28 100.7 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 EKX49630.1 - 9.4e-27 93.1 0.4 2.2e-26 91.9 0.4 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.28 EKX49630.1 - 6.2e-18 63.8 0.5 7.7e-06 25.5 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX49630.1 - 1.2e-16 59.4 3.1 0.00033 20.5 0.0 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 EKX49630.1 - 9.1e-11 41.4 1.6 0.00036 20.7 0.1 3.6 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX49630.1 - 1.6e-09 37.3 0.1 0.00097 18.8 0.0 3.6 1 1 2 3 3 3 3 TPR repeat TPR_8 PF13181.6 EKX49630.1 - 6.1e-09 35.4 0.3 0.031 14.5 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX49630.1 - 6.5e-08 32.6 0.1 0.0014 18.7 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX49630.1 - 1.1e-07 32.1 2.0 0.06 14.2 0.2 4.3 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX49630.1 - 1.5e-07 31.9 4.3 0.00046 20.8 1.0 2.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 EKX49630.1 - 9.7e-06 26.0 0.2 0.023 15.2 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX49630.1 - 0.00044 20.7 2.5 0.0062 17.1 0.3 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX49630.1 - 0.0033 17.7 6.4 1.6 9.1 0.2 3.4 2 1 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX49630.1 - 0.0062 16.7 2.9 0.036 14.3 1.1 2.5 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EKX49630.1 - 0.015 15.2 0.4 12 6.2 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX49630.1 - 0.034 14.2 1.2 0.52 10.4 0.0 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.9 EKX49630.1 - 0.045 13.2 1.3 0.11 11.9 0.0 2.3 3 0 0 3 3 3 0 SHNi-TPR TPR_10 PF13374.6 EKX49630.1 - 0.58 10.1 4.7 40 4.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PhyH PF05721.13 EKX49631.1 - 1.5e-09 38.4 0.1 2e-08 34.8 0.1 2.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.6 EKX49631.1 - 0.0038 18.1 0.0 0.0068 17.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1479 PF07350.12 EKX49631.1 - 0.048 12.4 0.0 0.33 9.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) Methyltransf_16 PF10294.9 EKX49632.1 - 1e-18 67.7 0.1 1.1e-09 38.3 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase PrmA PF06325.13 EKX49632.1 - 6.7e-06 25.7 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EKX49632.1 - 2e-05 24.2 0.0 3.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EKX49632.1 - 0.00023 21.8 0.0 0.0013 19.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX49632.1 - 0.0015 19.1 0.1 0.0062 17.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX49632.1 - 0.0025 17.7 0.0 0.0044 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX49632.1 - 0.0033 18.1 0.1 0.01 16.5 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX49632.1 - 0.0039 17.0 0.0 0.0083 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MtrC PF04211.13 EKX49632.1 - 0.14 11.2 0.1 0.21 10.6 0.1 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit C TehB PF03848.14 EKX49632.1 - 0.16 11.4 0.1 0.48 9.8 0.0 1.8 2 0 0 2 2 2 0 Tellurite resistance protein TehB CPBP PF02517.16 EKX49633.1 - 1.6e-19 70.0 3.7 4.1e-19 68.7 3.7 1.7 1 0 0 1 1 1 1 CPBP intramembrane metalloprotease LSM PF01423.22 EKX49634.1 - 1.4e-18 66.3 0.4 1.8e-18 66.0 0.4 1.1 1 0 0 1 1 1 1 LSM domain BPL_C PF02237.17 EKX49634.1 - 0.0027 17.5 0.3 0.0058 16.5 0.3 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain SM-ATX PF14438.6 EKX49634.1 - 0.026 14.7 0.1 0.032 14.4 0.1 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain EPSP_synthase PF00275.20 EKX49636.1 - 3.7e-122 408.0 0.0 5.1e-122 407.5 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 EKX49636.1 - 9.9e-97 323.2 1.2 1.3e-95 319.5 0.2 2.8 3 0 0 3 3 3 1 3-dehydroquinate synthase DHquinase_I PF01487.15 EKX49636.1 - 7.5e-43 147.4 0.0 1.6e-42 146.3 0.0 1.6 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 EKX49636.1 - 5.5e-32 111.1 0.1 6.1e-31 107.7 0.0 2.5 3 0 0 3 3 3 1 Shikimate kinase Shikimate_dh_N PF08501.11 EKX49636.1 - 9.8e-22 77.0 0.0 2.1e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 EKX49636.1 - 1.5e-08 34.7 0.2 8.8e-08 32.1 0.1 2.1 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 EKX49636.1 - 1.2e-05 25.0 0.0 3.9e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 EKX49636.1 - 1.8e-05 24.8 0.0 4.3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 EKX49636.1 - 0.00012 22.8 0.1 0.0008 20.2 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold AAA_33 PF13671.6 EKX49636.1 - 0.0027 17.9 0.1 0.011 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EKX49636.1 - 0.0075 16.8 0.0 0.017 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sacchrp_dh_NADP PF03435.18 EKX49636.1 - 0.0077 16.5 0.0 0.03 14.6 0.0 2.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AAA_16 PF13191.6 EKX49636.1 - 0.0078 16.6 0.1 0.11 12.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EKX49636.1 - 0.023 15.1 0.0 0.073 13.5 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EKX49636.1 - 0.023 14.7 0.1 0.29 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fe-ADH PF00465.19 EKX49636.1 - 0.026 13.4 2.8 2.6 6.8 0.1 3.6 3 0 0 3 3 3 0 Iron-containing alcohol dehydrogenase AAA_22 PF13401.6 EKX49636.1 - 0.14 12.4 0.0 0.45 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EKX49636.1 - 0.18 11.8 0.2 0.72 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EKX49636.1 - 0.18 11.5 0.0 0.43 10.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RCC1_2 PF13540.6 EKX49637.1 - 3.6e-06 26.6 0.9 8.3e-06 25.5 0.2 2.0 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat CDC45 PF02724.14 EKX49637.1 - 2.8e-05 22.7 29.5 3e-05 22.6 29.5 1.0 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 EKX49637.1 - 0.002 16.4 34.0 0.002 16.4 34.0 1.0 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 EKX49637.1 - 0.011 15.2 36.7 0.012 15.1 36.7 1.0 1 0 0 1 1 1 0 SDA1 CPSF100_C PF13299.6 EKX49637.1 - 0.011 15.9 2.6 0.02 15.1 2.6 1.4 1 1 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Mpp10 PF04006.12 EKX49637.1 - 0.98 7.8 30.5 1.2 7.5 30.5 1.1 1 0 0 1 1 1 0 Mpp10 protein CobT PF06213.12 EKX49637.1 - 1.1 8.6 30.8 1.5 8.1 30.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SAPS PF04499.15 EKX49637.1 - 1.6 7.4 14.3 1.5 7.5 14.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 EKX49637.1 - 1.7 7.5 3.6 2 7.3 3.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RNA_pol_Rpc4 PF05132.14 EKX49637.1 - 2.8 8.3 6.5 4.4 7.7 6.5 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 RCC1_2 PF13540.6 EKX49638.1 - 1.1e-20 72.9 25.4 2e-06 27.4 0.1 6.3 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EKX49638.1 - 1.8 9.3 0.0 1.8 9.3 0.0 5.6 4 2 1 5 5 5 0 Regulator of chromosome condensation (RCC1) repeat O-FucT PF10250.9 EKX49639.1 - 2.2e-25 90.1 0.6 2.1e-18 67.1 0.0 2.5 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase SPO22 PF08631.10 EKX49639.1 - 0.021 14.3 0.6 0.15 11.5 0.2 2.0 1 1 1 2 2 2 0 Meiosis protein SPO22/ZIP4 like EamA PF00892.20 EKX49640.1 - 1.9e-06 28.1 13.1 9.3e-06 25.9 12.5 3.2 3 0 0 3 3 3 2 EamA-like transporter family Ribosomal_L11_N PF03946.14 EKX49641.1 - 3.5e-19 68.4 0.5 6.5e-19 67.5 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EKX49641.1 - 3.1e-17 62.8 0.4 3.1e-17 62.8 0.4 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Poly_export PF02563.16 EKX49641.1 - 0.071 13.3 0.0 21 5.4 0.0 3.0 3 0 0 3 3 3 0 Polysaccharide biosynthesis/export protein Ribosomal_L7Ae PF01248.26 EKX49641.1 - 0.09 12.5 0.6 0.14 11.9 0.6 1.4 1 1 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RabGAP-TBC PF00566.18 EKX49642.1 - 2.9e-45 154.6 0.1 1.7e-44 152.0 0.1 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Ank_4 PF13637.6 EKX49642.1 - 3.2e-16 59.5 0.0 4.8e-09 36.6 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX49642.1 - 1.5e-15 57.5 0.0 1.7e-06 28.5 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 EKX49642.1 - 3.8e-15 55.5 0.1 5.2e-05 23.5 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EKX49642.1 - 5.6e-11 41.7 0.0 0.0004 20.6 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EKX49642.1 - 3.7e-10 39.9 0.0 5.1e-08 33.0 0.1 3.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) PRIMA1 PF16101.5 EKX49642.1 - 2.3 8.3 4.3 1.7 8.7 1.1 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 RWP-RK PF02042.15 EKX49643.1 - 1.7e-10 40.7 0.1 2.6e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain PCIF1_WW PF12237.8 EKX49644.1 - 2.4e-41 141.2 1.6 4.7e-40 137.0 1.6 2.2 1 1 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain WW PF00397.26 EKX49644.1 - 1.1e-06 28.6 4.7 8.9e-05 22.5 3.1 2.6 2 0 0 2 2 2 2 WW domain DnaJ PF00226.31 EKX49646.1 - 5.5e-25 87.3 2.9 1.3e-24 86.1 2.9 1.7 1 0 0 1 1 1 1 DnaJ domain Prp18 PF02840.15 EKX49646.1 - 0.58 10.2 2.7 7.6 6.6 0.1 2.7 3 0 0 3 3 3 0 Prp18 domain SnoaL_2 PF12680.7 EKX49647.1 - 4.3e-09 36.9 0.0 5.6e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain WW PF00397.26 EKX49648.1 - 0.00038 20.5 0.3 0.00095 19.2 0.3 1.7 1 0 0 1 1 1 1 WW domain WW PF00397.26 EKX49649.1 - 1.6e-05 24.9 0.3 9.2e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 WW domain Ank_2 PF12796.7 EKX49650.1 - 6e-31 106.9 0.1 4.9e-13 49.5 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX49650.1 - 5.9e-29 100.1 6.4 6.3e-11 42.6 0.4 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX49650.1 - 3.4e-22 78.2 0.6 1.3e-07 31.7 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX49650.1 - 4.4e-22 75.8 0.3 9.3e-05 22.5 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 EKX49650.1 - 2.3e-15 56.3 0.1 0.00027 21.3 0.0 4.8 5 0 0 5 5 5 4 Ankyrin repeat ATP-grasp_4 PF13535.6 EKX49651.1 - 6.8e-14 51.8 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EKX49651.1 - 1.4e-06 28.4 0.0 7.4e-06 26.1 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain LAL_C2 PF18603.1 EKX49651.1 - 7.6e-06 26.0 0.0 1.4e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 L-amino acid ligase C-terminal domain 2 GARS_A PF01071.19 EKX49651.1 - 0.0039 17.0 0.0 0.053 13.3 0.0 2.3 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_N PF18130.1 EKX49651.1 - 0.018 15.6 0.0 0.05 14.2 0.0 1.8 1 0 0 1 1 1 0 ATP-grasp N-terminal domain Dala_Dala_lig_C PF07478.13 EKX49651.1 - 0.061 12.9 0.1 2.9 7.4 0.1 2.3 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EKX49651.1 - 0.071 12.9 0.0 0.35 10.6 0.0 2.0 1 1 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.6 EKX49652.1 - 1.7e-14 53.7 0.0 2.2e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EKX49652.1 - 1.8e-07 31.4 0.0 3.5e-07 30.4 0.0 1.5 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EKX49652.1 - 2e-05 24.4 0.0 8.2e-05 22.5 0.0 2.0 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.22 EKX49652.1 - 0.00044 19.9 0.1 0.0023 17.5 0.1 2.1 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EKX49652.1 - 0.0095 15.5 0.0 0.18 11.3 0.0 2.2 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATPgrasp_N PF18130.1 EKX49652.1 - 0.013 16.0 0.0 0.25 11.9 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp N-terminal domain CPSase_L_D2 PF02786.17 EKX49652.1 - 0.028 13.9 0.0 0.044 13.3 0.0 1.4 1 1 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.6 EKX49652.1 - 0.052 13.3 0.3 0.52 10.1 0.3 2.2 1 1 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon PDZ_6 PF17820.1 EKX49654.1 - 5.5e-08 32.5 0.7 5.2e-07 29.4 0.4 2.7 4 0 0 4 4 4 1 PDZ domain PDZ PF00595.24 EKX49654.1 - 1.6e-06 28.4 0.1 3.5e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 PDZ domain TIR_2 PF13676.6 EKX49654.1 - 0.00052 20.6 0.0 0.0015 19.1 0.0 1.8 1 0 0 1 1 1 1 TIR domain PDZ_2 PF13180.6 EKX49654.1 - 0.032 14.6 0.0 0.11 12.9 0.0 1.9 1 0 0 1 1 1 0 PDZ domain Dimer_Tnp_hAT PF05699.14 EKX49654.1 - 0.07 12.9 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region Microcephalin PF12258.8 EKX49654.1 - 0.094 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Microcephalin protein SNF2_N PF00176.23 EKX49655.1 - 3.6e-46 157.5 0.0 1.4e-45 155.6 0.0 2.0 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX49655.1 - 2.1e-16 60.2 0.1 5.7e-16 58.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Y_Y_Y PF07495.13 EKX49655.1 - 0.014 15.3 0.0 0.041 13.8 0.0 1.8 1 0 0 1 1 1 0 Y_Y_Y domain Ank_2 PF12796.7 EKX49656.1 - 7.4e-26 90.6 0.4 2.2e-14 53.8 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX49656.1 - 4.4e-22 75.8 0.2 0.00061 20.0 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 EKX49656.1 - 6.8e-19 68.0 0.1 1.5e-07 31.8 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX49656.1 - 1.8e-18 66.0 0.0 0.015 15.8 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EKX49656.1 - 5.5e-17 61.6 2.3 0.00075 19.7 0.1 5.0 1 1 3 5 5 5 5 Ankyrin repeats (many copies) Hpr_kinase_C PF07475.12 EKX49656.1 - 0.012 15.1 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain Glyoxalase_4 PF13669.6 EKX49656.1 - 0.09 13.1 0.0 0.18 12.1 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily LysM PF01476.20 EKX49657.1 - 1.1e-16 60.6 0.8 2.3e-07 30.8 0.0 2.7 2 0 0 2 2 2 2 LysM domain PI_PP_I PF18363.1 EKX49659.1 - 0.018 15.2 0.9 10 6.4 0.1 3.4 3 0 0 3 3 3 0 Phosphoinositide phosphatase insertion domain RelA_SpoT PF04607.17 EKX49659.1 - 0.066 13.5 2.7 2.9 8.2 0.3 2.6 2 0 0 2 2 2 0 Region found in RelA / SpoT proteins Peptidase_M76 PF09768.9 EKX49660.1 - 0.045 13.5 1.9 0.11 12.2 1.9 1.6 1 0 0 1 1 1 0 Peptidase M76 family LRR_8 PF13855.6 EKX49661.1 - 1.9e-83 274.1 57.7 1.1e-15 57.1 2.0 6.7 1 1 8 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 EKX49661.1 - 5.9e-27 93.3 23.0 3.4e-07 30.5 1.9 6.6 3 2 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX49661.1 - 2.5e-20 72.7 0.0 2.3e-07 30.8 0.0 3.1 1 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EKX49661.1 - 1.1e-14 52.7 20.0 0.74 10.6 0.1 9.6 10 1 0 10 10 10 5 Leucine Rich Repeat LRR_9 PF14580.6 EKX49661.1 - 2.3e-07 30.5 0.3 0.024 14.2 0.1 3.9 1 1 3 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.6 EKX49661.1 - 0.0094 15.9 27.5 1.7 8.9 0.2 8.0 10 0 0 10 10 10 3 Leucine Rich repeat LRR_3 PF07725.12 EKX49661.1 - 1.4 8.9 4.5 8.2 6.5 0.1 3.6 4 0 0 4 4 4 0 Leucine Rich Repeat WD40 PF00400.32 EKX49662.1 - 1.8e-17 63.4 0.5 5.6e-08 33.3 0.1 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX49662.1 - 4.6e-05 23.6 0.0 7.7e-05 22.9 0.0 1.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX49662.1 - 0.0036 16.3 0.0 0.011 14.7 0.0 1.6 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EKX49662.1 - 0.029 13.0 0.0 0.032 12.9 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 HARP PF07443.13 EKX49662.1 - 0.15 11.8 0.0 13 5.5 0.0 2.2 2 0 0 2 2 2 0 HepA-related protein (HARP) COMM_domain PF07258.14 EKX49663.1 - 4.3e-05 23.6 0.0 8.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 COMM domain DUF262 PF03235.14 EKX49664.1 - 0.013 15.7 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF262 ParBc PF02195.18 EKX49664.1 - 0.027 14.8 0.0 0.065 13.5 0.0 1.6 1 0 0 1 1 1 0 ParB-like nuclease domain DndB PF14072.6 EKX49664.1 - 0.15 11.2 0.1 0.37 9.9 0.0 1.5 2 0 0 2 2 2 0 DNA-sulfur modification-associated Gag_p12 PF01141.18 EKX49665.1 - 0.18 12.2 3.8 1 9.7 3.7 2.2 1 1 0 1 1 1 0 Gag polyprotein, inner coat protein p12 Nitroreductase PF00881.24 EKX49665.1 - 0.33 11.0 3.7 0.26 11.3 1.2 2.0 2 1 0 2 2 2 0 Nitroreductase family RWP-RK PF02042.15 EKX49666.1 - 2.4e-15 56.2 0.0 5.5e-15 55.1 0.0 1.6 2 0 0 2 2 2 1 RWP-RK domain U-box PF04564.15 EKX49667.1 - 9.5e-16 57.7 0.0 2.9e-15 56.2 0.0 1.8 2 0 0 2 2 2 1 U-box domain PDZ_6 PF17820.1 EKX49667.1 - 0.00055 19.7 0.1 0.0011 18.7 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX49667.1 - 0.00065 20.0 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX49667.1 - 0.00094 19.5 0.5 0.0038 17.5 0.1 2.2 2 0 0 2 2 2 1 PDZ domain zf-NOSIP PF15906.5 EKX49667.1 - 0.0012 19.0 0.0 0.0031 17.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 EKX49667.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PH PF00169.29 EKX49667.1 - 0.097 13.2 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 PH domain PPR_3 PF13812.6 EKX49668.1 - 3.4e-08 33.5 0.1 3.3e-05 23.9 0.0 4.4 4 1 1 5 5 5 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 EKX49668.1 - 5e-06 26.6 0.0 0.0025 17.9 0.0 3.0 2 1 1 3 3 3 2 PPR repeat family PPR_long PF17177.4 EKX49668.1 - 0.02 14.3 0.1 0.35 10.2 0.0 2.0 1 1 1 2 2 2 0 Pentacotripeptide-repeat region of PRORP Abhydrolase_1 PF00561.20 EKX49669.1 - 2.5e-09 37.2 0.0 0.00011 22.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EKX49669.1 - 2.6e-06 28.2 0.0 3.6e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 EKX49669.1 - 0.00065 19.6 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_4 PF08386.10 EKX49669.1 - 0.0012 18.9 0.0 0.0025 17.9 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein DUF1211 PF06736.11 EKX49669.1 - 0.0054 17.2 0.3 0.011 16.2 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1211) Hydrolase_4 PF12146.8 EKX49669.1 - 0.0058 15.9 0.0 0.0077 15.5 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EKX49669.1 - 0.0092 15.8 0.0 1.4 8.7 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Ndr PF03096.14 EKX49669.1 - 0.015 14.0 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Ndr family Thioesterase PF00975.20 EKX49669.1 - 0.043 13.9 0.0 0.099 12.7 0.0 1.6 1 1 0 1 1 1 0 Thioesterase domain FSH1 PF03959.13 EKX49669.1 - 0.12 12.1 0.1 0.96 9.1 0.1 2.1 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DnaJ PF00226.31 EKX49671.1 - 3.9e-18 65.3 0.3 5.8e-18 64.8 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 EKX49672.1 - 6.4e-08 32.1 0.4 0.0023 17.7 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat CBM_20 PF00686.19 EKX49672.1 - 2.9e-07 30.3 0.0 4.3e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Starch binding domain TPR_2 PF07719.17 EKX49672.1 - 3.3e-06 26.8 0.8 0.0028 17.7 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX49672.1 - 5.6e-06 26.8 3.1 0.00093 19.7 0.5 1.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX49672.1 - 1.9e-05 24.3 0.1 3.8e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 TPR repeat TPR_16 PF13432.6 EKX49672.1 - 3.4e-05 24.4 1.8 6.6e-05 23.5 1.8 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX49672.1 - 0.00093 19.8 3.1 0.0029 18.3 0.6 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 EKX49672.1 - 0.0011 19.4 2.5 0.0014 19.0 2.1 1.4 1 1 0 1 1 1 1 Bacterial transcriptional activator domain TPR_9 PF13371.6 EKX49672.1 - 0.0021 18.2 0.2 0.0038 17.3 0.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX49672.1 - 0.004 17.3 0.8 0.8 10.1 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX49672.1 - 0.006 16.8 0.2 0.012 15.8 0.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 ECH_2 PF16113.5 EKX49672.1 - 0.0093 15.5 0.1 0.012 15.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase NARP1 PF12569.8 EKX49672.1 - 0.011 14.7 0.5 0.013 14.5 0.5 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_MalT PF17874.1 EKX49672.1 - 0.02 14.3 0.0 0.023 14.0 0.0 1.1 1 0 0 1 1 1 0 MalT-like TPR region Alkyl_sulf_dimr PF14863.6 EKX49672.1 - 0.03 14.8 0.1 0.047 14.2 0.1 1.3 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation TPR_7 PF13176.6 EKX49672.1 - 0.16 12.1 0.9 0.87 9.8 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX49672.1 - 0.16 12.6 0.9 0.87 10.4 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat RNA_pol_Rpb1_5 PF04998.17 EKX49673.1 - 1.9e-93 312.8 0.1 6.1e-92 307.8 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 EKX49673.1 - 3.5e-90 302.5 0.0 5.3e-90 301.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 EKX49673.1 - 2.5e-72 242.5 0.2 4.6e-72 241.6 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EKX49673.1 - 1.1e-38 132.7 0.0 5e-38 130.5 0.0 2.2 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_6 PF04992.14 EKX49673.1 - 9.9e-34 116.8 3.1 5e-21 75.4 0.1 2.4 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_4 PF05000.17 EKX49673.1 - 3e-28 97.9 0.9 9.4e-27 93.1 0.2 3.1 2 1 1 3 3 3 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_7 PF04990.12 EKX49673.1 - 8e-23 80.9 0.1 1.8e-22 79.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 Radical_SAM PF04055.21 EKX49674.1 - 2.4e-16 60.6 0.0 3.9e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 EKX49674.1 - 3.8e-07 30.2 0.0 4e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 EKX49674.1 - 0.0028 17.9 0.0 0.0062 16.8 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Lectin_C PF00059.21 EKX49675.1 - 1.2e-20 74.2 9.0 1.7e-11 44.8 3.1 2.7 2 0 0 2 2 2 2 Lectin C-type domain TPR_2 PF07719.17 EKX49675.1 - 2.5e-14 52.1 0.1 0.0018 18.3 0.0 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX49675.1 - 2.3e-13 50.4 0.1 0.00038 20.9 0.0 6.0 3 1 3 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX49675.1 - 1.1e-10 42.0 15.0 0.069 13.8 0.1 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 EKX49675.1 - 1.5e-10 40.4 0.0 0.02 14.7 0.0 6.1 5 0 0 5 5 5 1 Tetratricopeptide repeat EGF_2 PF07974.13 EKX49675.1 - 4.2e-10 39.8 32.3 0.00012 22.4 13.1 3.4 2 0 0 2 2 2 2 EGF-like domain TPR_8 PF13181.6 EKX49675.1 - 6.4e-08 32.2 0.0 0.026 14.7 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX49675.1 - 1.1e-07 32.0 13.3 0.06 13.6 0.0 5.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX49675.1 - 1.6e-07 31.5 16.6 0.48 11.4 0.3 7.9 4 3 4 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX49675.1 - 1.1e-05 25.4 8.4 0.0037 17.4 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX49675.1 - 2.1e-05 24.7 1.8 0.00065 19.9 0.0 3.5 4 0 0 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EKX49675.1 - 0.0019 18.0 3.6 1.2 9.1 0.0 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX49675.1 - 0.0036 17.6 0.3 0.14 12.6 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX49675.1 - 0.0075 16.2 1.0 19 5.5 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EKX49675.1 - 0.016 14.9 1.9 2.7 7.6 0.1 3.5 3 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) BTAD PF03704.17 EKX49675.1 - 0.039 14.4 0.1 0.039 14.4 0.1 3.4 3 0 0 3 3 2 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 EKX49675.1 - 0.15 12.7 6.5 1.1e+02 3.7 0.3 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat EGF PF00008.27 EKX49675.1 - 0.17 12.2 28.3 0.65 10.4 9.3 3.5 3 0 0 3 3 2 0 EGF-like domain EGF_Tenascin PF18720.1 EKX49675.1 - 0.3 11.2 38.7 0.035 14.2 11.4 3.4 3 0 0 3 3 2 0 Tenascin EGF domain GAS PF13851.6 EKX49675.1 - 0.37 10.1 8.2 0.8 9.0 8.2 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding RhlB PF12300.8 EKX49675.1 - 1.1 9.3 6.1 3.1 7.9 6.1 1.7 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB Laminin_EGF PF00053.24 EKX49675.1 - 1.1 9.4 29.2 2.3 8.5 9.0 3.6 2 0 0 2 2 2 0 Laminin EGF domain hEGF PF12661.7 EKX49675.1 - 4 8.2 28.4 2.2 9.0 8.2 3.6 3 0 0 3 3 3 0 Human growth factor-like EGF tRNA-synt_2b PF00587.25 EKX49677.1 - 1.3e-37 129.5 0.0 3.2e-37 128.2 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EKX49677.1 - 4.4e-26 91.2 3.7 1e-25 90.1 3.7 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain MetOD2 PF18548.1 EKX49678.1 - 0.13 12.4 1.7 0.65 10.1 0.3 2.3 2 0 0 2 2 2 0 Metanogen output domain 2 Acyltransf_C PF16076.5 EKX49681.1 - 2.9e-18 65.7 0.2 5.7e-18 64.8 0.2 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 EKX49681.1 - 5.5e-15 55.2 0.0 8.5e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase HIT PF01230.23 EKX49681.1 - 0.14 13.0 0.2 0.35 11.6 0.2 1.6 1 0 0 1 1 1 0 HIT domain Ion_trans PF00520.31 EKX49682.1 - 2.4e-19 69.5 21.9 5e-19 68.5 21.9 1.4 1 1 0 1 1 1 1 Ion transport protein C2 PF00168.30 EKX49682.1 - 4.3e-08 33.4 0.4 9.7e-08 32.2 0.4 1.6 1 0 0 1 1 1 1 C2 domain PH PF00169.29 EKX49682.1 - 0.00011 22.6 0.0 0.00031 21.2 0.0 1.8 1 0 0 1 1 1 1 PH domain EF-hand_1 PF00036.32 EKX49682.1 - 0.048 13.2 0.6 3.4 7.4 0.0 3.1 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 EKX49682.1 - 0.058 13.4 1.2 7.8 6.7 0.1 3.1 2 0 0 2 2 2 0 EF-hand domain LRR_6 PF13516.6 EKX49684.1 - 7.4e-13 47.4 28.0 0.0039 17.1 0.2 7.6 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.7 EKX49684.1 - 2.9e-08 33.8 28.5 0.0017 18.7 0.7 5.2 1 1 5 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX49684.1 - 0.00081 19.6 15.3 8.7 7.3 0.1 7.7 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.6 EKX49684.1 - 0.0019 17.9 27.6 0.12 12.1 2.8 5.5 3 2 1 4 4 4 3 Leucine rich repeat F-box-like PF12937.7 EKX49684.1 - 0.062 13.2 0.2 0.2 11.6 0.2 1.9 1 0 0 1 1 1 0 F-box-like DNA_pol_A PF00476.20 EKX49684.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase family A Peptidase_U32 PF01136.19 EKX49685.1 - 0.077 12.1 0.8 0.58 9.3 0.0 2.3 2 0 0 2 2 2 0 Peptidase family U32 Mtc PF03820.17 EKX49686.1 - 2.7e-90 302.6 0.0 3.2e-90 302.3 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier His_Phos_1 PF00300.22 EKX49688.1 - 5.9e-08 32.6 7.5 0.00054 19.7 0.9 4.2 2 2 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) UPF0147 PF03685.13 EKX49688.1 - 0.1 12.6 0.2 1.3 9.1 0.0 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0147) DUF2723 PF11028.8 EKX49689.1 - 2.3e-29 102.5 7.5 3.3e-29 102.0 5.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2723) PMT_2 PF13231.6 EKX49689.1 - 5.1e-06 26.8 5.3 5.1e-06 26.8 5.3 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT PF02366.18 EKX49689.1 - 1.4 8.5 10.5 0.11 12.1 5.3 1.8 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase HIT PF01230.23 EKX49690.1 - 1.3e-25 89.9 0.0 1.9e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EKX49690.1 - 2.3e-23 82.8 0.0 3.2e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GST_N_3 PF13417.6 EKX49691.1 - 1.7e-14 54.0 0.0 2.7e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EKX49691.1 - 5.1e-07 29.9 0.0 8.8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EKX49691.1 - 1.6e-05 25.1 0.0 2.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EKX49691.1 - 0.00014 21.8 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EKX49691.1 - 0.00079 20.0 0.0 0.0013 19.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EKX49691.1 - 0.0047 17.6 0.0 0.0079 16.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C PF00043.25 EKX49691.1 - 0.0098 16.1 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EKX49691.1 - 0.018 15.2 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EKX49691.1 - 0.14 11.9 0.0 0.29 11.0 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Peptidase_M22 PF00814.25 EKX49692.1 - 5.3e-89 298.5 0.0 6.1e-89 298.3 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 EKX49692.1 - 0.17 11.5 0.1 3.3 7.3 0.1 2.2 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus DUF167 PF02594.16 EKX49693.1 - 2e-18 66.3 0.8 4.1e-10 39.6 0.1 2.2 2 0 0 2 2 2 2 Uncharacterised ACR, YggU family COG1872 DUF4530 PF15039.6 EKX49693.1 - 0.058 13.5 0.0 0.34 11.1 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4530) Acyltransferase PF01553.21 EKX49694.1 - 5.1e-14 52.0 0.0 7e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Kelch_1 PF01344.25 EKX49695.1 - 4.8e-29 99.7 0.8 4.7e-08 32.5 0.0 4.6 4 1 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 EKX49695.1 - 6.2e-18 64.4 0.7 6.4e-07 29.4 0.0 5.0 3 2 1 4 4 4 3 Kelch motif Kelch_4 PF13418.6 EKX49695.1 - 5.2e-10 39.2 0.2 0.083 12.9 0.5 3.6 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_2 PF07646.15 EKX49695.1 - 2e-09 37.0 1.0 1.6e-05 24.7 0.0 4.1 4 1 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 EKX49695.1 - 3.8e-07 30.2 6.3 0.86 10.0 0.4 5.1 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EKX49695.1 - 2.1e-06 27.6 0.8 0.029 14.3 0.2 3.8 4 0 0 4 4 4 2 Kelch motif Semialdhyde_dhC PF02774.18 EKX49697.1 - 3e-45 154.6 0.0 4e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EKX49697.1 - 2.1e-26 92.7 0.2 3.6e-26 92.0 0.2 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 EKX49697.1 - 0.0001 21.9 0.2 0.0079 15.8 0.0 2.6 3 0 0 3 3 3 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain F420_oxidored PF03807.17 EKX49697.1 - 0.00031 21.3 0.2 0.00074 20.1 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.20 EKX49697.1 - 0.2 11.8 1.4 0.43 10.7 1.4 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DEC-1_N PF04625.13 EKX49700.1 - 0.049 12.6 1.3 0.063 12.3 1.3 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF5486 PF17588.2 EKX49700.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5486) IKBKB_SDD PF18397.1 EKX49700.1 - 0.14 11.4 0.0 0.4 10.0 0.1 1.6 2 0 0 2 2 2 0 IQBAL scaffold dimerization domain Glyco_transf_49 PF13896.6 EKX49701.1 - 1.6e-17 63.9 0.0 5.3e-17 62.2 0.0 1.7 1 1 1 2 2 2 1 Glycosyl-transferase for dystroglycan LysM PF01476.20 EKX49701.1 - 5.2e-11 42.4 0.0 1e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 LysM domain UCR_TM PF02921.14 EKX49702.1 - 3.2e-12 46.8 0.4 5.4e-12 46.0 0.1 1.6 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 EKX49702.1 - 3.1e-11 43.1 0.0 4.7e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain TPR_14 PF13428.6 EKX49703.1 - 0.017 15.9 1.8 15 6.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Isy1 PF06246.12 EKX49704.1 - 4.7e-87 291.8 4.4 5.3e-87 291.6 4.4 1.0 1 0 0 1 1 1 1 Isy1-like splicing family DEAD PF00270.29 EKX49705.1 - 9.5e-28 97.1 0.0 1.4e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EKX49705.1 - 4.2e-05 23.6 0.0 6.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EKX49705.1 - 6.8e-05 23.2 0.0 0.016 15.6 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain Presenilin PF01080.17 EKX49706.1 - 0.0091 14.8 7.9 0.014 14.2 7.9 1.3 1 0 0 1 1 1 1 Presenilin DUF4083 PF13314.6 EKX49706.1 - 0.13 12.2 0.1 0.34 10.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) DDHD PF02862.17 EKX49706.1 - 0.6 10.2 1.8 1.6 8.9 1.8 1.7 1 0 0 1 1 1 0 DDHD domain Baculo_PEP_C PF04513.12 EKX49707.1 - 3.6e-06 27.1 8.1 0.23 11.5 0.4 4.3 1 1 4 5 5 5 3 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 EKX49707.1 - 0.00084 19.8 8.4 1.8 9.1 0.3 4.8 1 1 2 4 4 4 2 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 EKX49707.1 - 0.0043 17.5 18.8 0.05 14.1 1.1 4.6 1 1 3 4 4 4 2 Protein of unknown function DUF16 EzrA PF06160.12 EKX49707.1 - 0.0059 14.8 19.2 0.0074 14.5 14.1 2.1 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA DUF3584 PF12128.8 EKX49707.1 - 0.017 12.7 31.2 0.003 15.2 19.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) UBN_AB PF14075.6 EKX49707.1 - 0.039 13.7 0.9 0.039 13.7 0.9 2.4 1 1 1 2 2 2 0 Ubinuclein conserved middle domain DUF1664 PF07889.12 EKX49707.1 - 0.039 14.0 19.3 3.9 7.5 3.9 4.5 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) Lebercilin PF15619.6 EKX49707.1 - 0.041 13.5 0.3 0.041 13.5 0.3 4.1 2 1 1 3 3 2 0 Ciliary protein causing Leber congenital amaurosis disease Nuc_N PF14448.6 EKX49707.1 - 0.066 13.1 0.3 0.066 13.1 0.3 2.6 4 0 0 4 4 3 0 Nuclease N terminal Fib_alpha PF08702.10 EKX49707.1 - 0.18 11.9 21.3 0.88 9.7 3.3 3.6 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family SpoIISA_toxin PF14171.6 EKX49707.1 - 0.22 11.2 3.0 11 5.7 0.4 2.7 1 1 0 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system DUF948 PF06103.11 EKX49707.1 - 0.24 11.7 8.0 2 8.7 0.1 3.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Exonuc_VII_L PF02601.15 EKX49707.1 - 0.36 10.3 28.8 1.4e+04 -4.7 28.8 2.7 1 1 0 1 1 0 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 EKX49707.1 - 0.51 8.2 13.1 1.6 6.6 1.1 2.3 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family TMPIT PF07851.13 EKX49707.1 - 0.64 9.2 23.7 0.04 13.2 1.4 3.5 1 1 3 4 4 4 0 TMPIT-like protein HSBP1 PF06825.12 EKX49707.1 - 0.64 9.9 0.0 0.64 9.9 0.0 3.5 5 0 0 5 5 3 0 Heat shock factor binding protein 1 Spc7 PF08317.11 EKX49707.1 - 0.75 8.6 35.3 0.68 8.7 7.2 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF4407 PF14362.6 EKX49707.1 - 2 7.7 18.1 0.96 8.7 1.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) RapH_N PF18801.1 EKX49707.1 - 2.9 8.0 6.3 23 5.1 0.1 3.9 4 0 0 4 4 4 0 response regulator aspartate phosphatase H, N terminal XhlA PF10779.9 EKX49707.1 - 4.4 7.6 11.7 8.9 6.6 1.2 4.4 4 0 0 4 4 4 0 Haemolysin XhlA UPF0242 PF06785.11 EKX49707.1 - 9.5 6.3 31.3 1.4 9.0 10.5 3.5 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Ephrin_rec_like PF07699.13 EKX49709.1 - 8.7e-15 54.2 31.1 2e-08 33.9 9.2 4.4 1 1 3 4 4 4 4 Putative ephrin-receptor like PDZ_2 PF13180.6 EKX49710.1 - 0.00031 21.0 0.0 0.00054 20.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain SHOCT PF09851.9 EKX49710.1 - 0.00057 19.5 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 Short C-terminal domain PDZ_6 PF17820.1 EKX49710.1 - 0.00061 19.6 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX49710.1 - 0.0011 19.3 0.0 0.0024 18.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain FOXP-CC PF16159.5 EKX49711.1 - 0.65 10.7 4.7 48 4.7 0.0 3.7 3 1 0 3 3 3 0 FOXP coiled-coil domain RhoGAP PF00620.27 EKX49711.1 - 2.4 8.0 7.4 1.7 8.4 0.8 2.4 2 0 0 2 2 2 0 RhoGAP domain Pepdidase_M14_N PF18027.1 EKX49712.1 - 1.5e-12 47.8 0.1 3.7e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 EKX49712.1 - 2e-09 37.7 0.0 8.1e-09 35.7 0.0 2.0 1 1 0 1 1 1 1 Zinc carboxypeptidase MCR_alpha_N PF02745.15 EKX49712.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, N-terminal domain AstE_AspA PF04952.14 EKX49712.1 - 0.19 10.8 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family Laminin_G_3 PF13385.6 EKX49713.1 - 9.1e-17 61.6 1.8 2.3e-16 60.3 0.4 2.3 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Ricin_B_lectin PF00652.22 EKX49713.1 - 1.2e-08 35.2 0.0 2.6e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain LysM PF01476.20 EKX49713.1 - 1.6e-05 24.8 0.1 8.2e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 LysM domain RicinB_lectin_2 PF14200.6 EKX49713.1 - 0.00071 20.3 0.2 0.0024 18.6 0.2 2.0 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Big_7 PF17957.1 EKX49713.1 - 0.73 10.6 10.8 0.062 14.1 0.9 4.1 4 2 1 5 5 5 0 Bacterial Ig domain IQ PF00612.27 EKX49716.1 - 3.2e-11 42.0 26.5 0.0011 18.5 0.6 6.1 5 0 0 5 5 5 5 IQ calmodulin-binding motif Myc_N PF01056.18 EKX49716.1 - 7.7 6.3 12.5 15 5.4 0.0 2.5 2 0 0 2 2 2 0 Myc amino-terminal region SET PF00856.28 EKX49717.1 - 0.0018 18.7 0.0 0.0064 16.9 0.0 1.9 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 EKX49717.1 - 0.0022 18.7 2.3 0.006 17.3 2.3 1.8 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding FKBP_C PF00254.28 EKX49719.1 - 1.1e-20 73.8 0.0 1.5e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase CENP-B_dimeris PF09026.10 EKX49719.1 - 2.2 8.7 11.0 3.2 8.2 11.0 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2457 PF10446.9 EKX49719.1 - 9.5 5.2 9.0 12 4.8 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ank_2 PF12796.7 EKX49720.1 - 3.8e-27 94.7 0.0 9.1e-14 51.8 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX49720.1 - 7.5e-25 87.0 0.1 7.9e-12 45.4 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX49720.1 - 2.7e-19 69.0 0.3 1.3e-10 41.3 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX49720.1 - 8.7e-19 67.1 0.0 2.3e-06 27.8 0.0 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EKX49720.1 - 1.1e-18 65.3 0.0 2e-06 27.7 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat UPF0300 PF08594.10 EKX49720.1 - 0.0043 16.4 0.0 0.0052 16.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0300) Trns_repr_metal PF02583.17 EKX49720.1 - 0.036 14.4 0.3 0.055 13.8 0.3 1.3 1 0 0 1 1 1 0 Metal-sensitive transcriptional repressor Pentapeptide PF00805.22 EKX49721.1 - 1.8e-13 49.9 18.0 8.9e-07 28.4 2.3 3.8 2 1 2 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 EKX49721.1 - 2.9e-11 43.4 4.2 1.7e-07 31.3 1.4 2.1 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 EKX49721.1 - 1.3e-07 31.6 1.9 0.0092 16.1 2.5 3.4 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) DHFR_1 PF00186.19 EKX49722.1 - 0.11 12.2 0.0 3.4 7.3 0.0 2.1 1 1 1 2 2 2 0 Dihydrofolate reductase RuvA_C PF07499.13 EKX49722.1 - 0.28 11.7 1.5 12 6.5 0.0 2.8 3 0 0 3 3 3 0 RuvA, C-terminal domain PDZ PF00595.24 EKX49723.1 - 5.4e-08 33.1 0.0 6.7e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX49723.1 - 3.5e-07 30.0 0.0 4.7e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX49723.1 - 0.00016 21.9 0.0 0.00024 21.4 0.0 1.2 1 0 0 1 1 1 1 PDZ domain Poly_export PF02563.16 EKX49723.1 - 0.11 12.8 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis/export protein LRR_9 PF14580.6 EKX49725.1 - 1.9e-13 50.3 1.1 4.7e-13 49.0 1.1 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EKX49725.1 - 7.9e-10 38.8 11.8 0.011 16.1 0.1 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX49725.1 - 4.1e-07 29.7 13.0 8.1e-05 22.3 4.7 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 EKX49725.1 - 1.8 8.8 10.0 1.7 8.9 0.9 3.6 3 0 0 3 3 3 0 Leucine Rich repeat GSHPx PF00255.19 EKX49726.1 - 2.1e-45 152.7 0.2 3.7e-45 151.9 0.2 1.4 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 EKX49726.1 - 1e-10 41.6 0.0 2e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EKX49726.1 - 0.00015 21.5 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 Redoxin GST_C_3 PF14497.6 EKX49727.1 - 3.4e-14 52.8 0.0 6.1e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EKX49727.1 - 7.8e-10 38.8 0.0 1.6e-09 37.9 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EKX49727.1 - 3.6e-05 24.0 0.0 6.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EKX49727.1 - 9.9e-05 22.3 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EKX49727.1 - 0.00031 21.0 0.0 0.0011 19.3 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 EKX49727.1 - 0.00084 19.1 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EKX49727.1 - 0.0067 16.7 0.0 0.018 15.3 0.0 1.8 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein RRM_1 PF00076.22 EKX49728.1 - 0.0039 17.0 0.0 0.0079 16.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_transf_17 PF04724.13 EKX49730.1 - 4.7e-43 147.6 0.9 1.5e-37 129.5 0.0 3.5 2 2 0 2 2 2 2 Glycosyltransferase family 17 DUF563 PF04577.14 EKX49730.1 - 2.5e-15 57.2 0.9 8.5e-15 55.5 0.9 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF563) BiPBP_C PF06832.12 EKX49730.1 - 0.0013 18.8 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 Penicillin-Binding Protein C-terminus Family DUF2610 PF11020.8 EKX49730.1 - 0.053 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2610) Presenilin PF01080.17 EKX49730.1 - 0.55 8.9 2.5 0.84 8.3 2.5 1.1 1 0 0 1 1 1 0 Presenilin DUF3381 PF11861.8 EKX49730.1 - 1.3 8.8 15.5 2.7 7.8 15.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) U1snRNP70_N PF12220.8 EKX49730.1 - 1.8 9.3 8.3 4.9 7.9 8.3 1.7 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal CDC45 PF02724.14 EKX49730.1 - 1.9 6.7 8.5 3 6.0 8.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2828 PF11443.8 EKX49730.1 - 2.1 6.4 4.0 3.2 5.7 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) VIR_N PF15912.5 EKX49730.1 - 2.2 7.8 5.8 3.6 7.1 5.8 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal GST_C_3 PF14497.6 EKX49731.1 - 1.8e-13 50.5 0.0 2.8e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EKX49731.1 - 1.9e-09 37.6 0.0 2.9e-09 37.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EKX49731.1 - 3.3e-05 23.8 0.0 6.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EKX49731.1 - 0.00036 20.3 0.2 0.00097 18.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EKX49731.1 - 0.00037 20.8 0.0 0.00065 20.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EKX49731.1 - 0.0011 19.2 0.0 0.0021 18.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 EKX49731.1 - 0.0022 18.3 0.0 0.0089 16.3 0.0 1.8 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein TAF8_C PF10406.9 EKX49732.1 - 0.15 12.6 5.4 0.2 12.2 0.4 2.1 1 1 1 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term TIG PF01833.24 EKX49733.1 - 0.005 16.9 59.8 0.063 13.4 0.1 14.0 14 1 1 15 15 15 5 IPT/TIG domain Qn_am_d_aIII PF09099.10 EKX49733.1 - 0.041 14.3 0.9 1.3e+02 3.0 0.0 5.7 6 0 0 6 6 6 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III DUF1096 PF06493.11 EKX49733.1 - 3.3 8.2 6.4 17 6.0 6.4 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1096) FAM176 PF14851.6 EKX49734.1 - 0.058 13.1 0.1 0.064 12.9 0.1 1.2 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.10 EKX49734.1 - 0.2 12.1 5.1 0.3 11.5 5.1 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Neurochondrin PF05536.11 EKX49735.1 - 8.6e-30 103.7 0.0 1.7e-29 102.7 0.0 1.4 1 1 0 1 1 1 1 Neurochondrin Exog_C PF18026.1 EKX49735.1 - 0.13 12.4 0.7 0.48 10.5 0.7 2.0 1 0 0 1 1 1 0 Endo/exonuclease (EXOG) C-terminal domain TPR_2 PF07719.17 EKX49736.1 - 4.6e-05 23.2 8.1 0.00038 20.3 0.2 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX49736.1 - 0.00023 20.9 1.0 0.0033 17.3 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX49736.1 - 0.0022 17.7 1.0 0.012 15.5 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Glyco_transf_4 PF13439.6 EKX49736.1 - 0.012 15.6 0.6 0.039 13.9 0.1 2.1 2 0 0 2 2 2 0 Glycosyltransferase Family 4 TPR_11 PF13414.6 EKX49736.1 - 0.02 14.6 0.1 0.048 13.4 0.1 1.6 1 0 0 1 1 1 0 TPR repeat TPR_12 PF13424.6 EKX49736.1 - 0.042 14.2 1.0 0.21 11.9 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2309 PF10070.9 EKX49736.1 - 0.049 12.0 0.9 0.073 11.4 0.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) TPR_10 PF13374.6 EKX49736.1 - 0.062 13.2 0.0 0.25 11.2 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX49736.1 - 0.24 12.3 8.7 15 6.7 0.0 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX49736.1 - 0.67 10.5 2.5 47 4.6 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EKX49736.1 - 0.91 10.2 9.6 2.3 9.0 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat AD PF09793.9 EKX49737.1 - 2.4e-17 62.8 0.0 3.4e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain cNMP_binding PF00027.29 EKX49738.1 - 0.0023 18.0 0.0 0.035 14.2 0.0 2.4 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain NAD_binding_2 PF03446.15 EKX49739.1 - 5.6e-41 140.3 0.0 8.8e-41 139.7 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EKX49739.1 - 6.1e-27 94.3 0.3 9.8e-27 93.6 0.3 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EKX49739.1 - 1.2e-09 38.6 0.0 2.3e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 EKX49739.1 - 1.8e-06 27.7 0.0 2.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 EKX49739.1 - 2.2e-06 27.8 0.0 3.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EKX49739.1 - 6.5e-05 22.4 0.1 0.00011 21.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EKX49739.1 - 0.00013 21.5 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Sacchrp_dh_NADP PF03435.18 EKX49739.1 - 0.0015 18.8 0.1 0.0024 18.2 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 EKX49739.1 - 0.0042 17.1 0.0 0.013 15.4 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 EKX49739.1 - 0.0048 16.8 0.1 0.0077 16.1 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PDH PF02153.17 EKX49739.1 - 0.0067 15.5 0.0 0.0087 15.1 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase TrkA_N PF02254.18 EKX49739.1 - 0.022 15.0 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 EKX49739.1 - 0.16 11.6 0.2 0.32 10.6 0.2 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain COG5 PF10392.9 EKX49740.1 - 0.51 10.5 5.7 1.1 9.5 5.7 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Endonuc_Holl PF10107.9 EKX49740.1 - 8.9 6.1 11.7 24 4.7 0.1 3.0 1 1 2 3 3 3 0 Endonuclease related to archaeal Holliday junction resolvase Fez1 PF06818.15 EKX49740.1 - 9.9 6.6 26.7 3.8 7.9 15.5 2.5 1 1 1 2 2 2 0 Fez1 zf-DBF PF07535.12 EKX49741.1 - 3.7e-05 23.7 0.2 7.7e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 DBF zinc finger NicO PF03824.16 EKX49742.1 - 3.1 7.0 18.0 6.3 6.1 18.0 1.4 1 0 0 1 1 1 0 High-affinity nickel-transport protein ACT_4 PF13291.6 EKX49743.1 - 0.14 12.8 2.7 3.4 8.3 0.2 3.1 3 1 0 3 3 3 0 ACT domain zf-CRD PF17979.1 EKX49743.1 - 0.15 12.2 0.1 12 5.9 0.1 2.3 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions BSD PF03909.17 EKX49746.1 - 1.8e-09 37.5 0.1 3e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 BSD domain PNGaseA PF12222.8 EKX49746.1 - 0.014 14.3 0.0 0.018 13.9 0.0 1.1 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A EF-hand_8 PF13833.6 EKX49747.1 - 0.0025 17.6 0.2 0.3 10.9 0.0 3.0 2 1 1 3 3 3 2 EF-hand domain pair FAM176 PF14851.6 EKX49747.1 - 0.64 9.7 0.0 0.64 9.7 0.0 5.5 4 1 1 5 5 5 0 FAM176 family TPR_12 PF13424.6 EKX49748.1 - 0.0021 18.3 2.9 0.23 11.8 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX49748.1 - 0.0027 17.2 1.5 0.016 14.6 0.6 2.0 2 0 0 2 2 2 1 MalT-like TPR region TPR_8 PF13181.6 EKX49748.1 - 0.051 13.8 0.5 2.7 8.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF5332 PF17266.2 EKX49748.1 - 1.2 8.8 5.1 1.1 8.9 1.2 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5332) DUF179 PF02622.15 EKX49749.1 - 6.3e-09 36.0 0.0 9e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 TPR_MLP1_2 PF07926.12 EKX49750.1 - 0.0096 16.0 24.6 0.0096 16.0 24.6 9.9 4 3 4 9 9 9 3 TPR/MLP1/MLP2-like protein Hema_stalk PF08720.10 EKX49750.1 - 0.85 9.3 2.4 2.1 8.0 0.4 2.5 1 1 1 2 2 2 0 Influenza C hemagglutinin stalk PhosphMutase PF10143.9 EKX49751.1 - 1.5e-53 181.2 0.0 2.5e-53 180.4 0.0 1.4 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 EKX49751.1 - 3.1e-21 75.9 0.0 4.2e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF4410 PF14366.6 EKX49751.1 - 0.00076 19.4 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4410) Phosphodiest PF01663.22 EKX49751.1 - 0.0014 18.2 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Alk_phosphatase PF00245.20 EKX49751.1 - 0.042 12.8 0.1 0.062 12.3 0.1 1.1 1 0 0 1 1 1 0 Alkaline phosphatase His_Phos_1 PF00300.22 EKX49752.1 - 2.2e-19 69.9 0.4 1.9e-18 66.9 0.4 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HECT PF00632.25 EKX49753.1 - 1.3e-84 284.3 0.0 1.5e-84 284.1 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) KH_1 PF00013.29 EKX49754.1 - 7.4e-28 96.2 4.8 4.3e-09 36.1 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EKX49754.1 - 1.4e-05 24.9 0.5 0.093 12.6 0.0 2.9 3 0 0 3 3 3 2 KH domain KH_2 PF07650.17 EKX49754.1 - 0.00027 20.7 1.3 0.17 11.7 0.3 3.3 3 0 0 3 3 3 2 KH domain SHOCT PF09851.9 EKX49755.1 - 0.00032 20.3 0.1 0.00059 19.5 0.1 1.4 1 0 0 1 1 1 1 Short C-terminal domain DUF4349 PF14257.6 EKX49756.1 - 0.055 12.9 5.3 0.23 10.9 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4349) KLRAQ PF10205.9 EKX49756.1 - 0.26 11.6 22.3 0.043 14.1 5.6 4.3 4 2 1 5 5 5 0 Predicted coiled-coil domain-containing protein Val_tRNA-synt_C PF10458.9 EKX49756.1 - 0.44 10.9 0.1 0.44 10.9 0.1 4.0 5 0 0 5 5 5 0 Valyl tRNA synthetase tRNA binding arm DUF948 PF06103.11 EKX49756.1 - 0.56 10.5 5.1 1.7 8.9 0.2 3.7 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF1993 PF09351.10 EKX49756.1 - 0.88 9.7 3.9 1.7 8.8 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1993) SKA2 PF16740.5 EKX49756.1 - 5.5 6.8 9.9 5.9 6.7 0.2 4.1 3 1 0 3 3 3 0 Spindle and kinetochore-associated protein 2 PilJ PF13675.6 EKX49756.1 - 5.7 7.0 8.4 6.9 6.7 0.4 4.2 3 2 2 5 5 5 0 Type IV pili methyl-accepting chemotaxis transducer N-term TSC22 PF01166.18 EKX49756.1 - 8 6.9 11.2 7.5 7.0 0.1 4.1 4 0 0 4 4 4 0 TSC-22/dip/bun family Mito_carr PF00153.27 EKX49757.1 - 1e-26 92.7 0.5 2.7e-23 81.7 0.2 2.4 2 1 0 2 2 2 2 Mitochondrial carrier protein Methyltr_RsmB-F PF01189.17 EKX49758.1 - 1e-21 77.5 0.0 1.3e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F HEM4 PF02602.15 EKX49758.1 - 0.00051 19.5 0.0 0.00057 19.3 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD FtsJ PF01728.19 EKX49758.1 - 0.093 12.8 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_24 PF13578.6 EKX49758.1 - 0.14 13.2 0.0 0.2 12.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF296 PF03479.15 EKX49759.1 - 4.4e-24 84.9 0.3 5.1e-24 84.7 0.3 1.0 1 0 0 1 1 1 1 Plants and Prokaryotes Conserved (PCC) domain Gln-synt_C PF00120.24 EKX49759.1 - 0.2 10.6 0.3 0.26 10.2 0.3 1.1 1 0 0 1 1 1 0 Glutamine synthetase, catalytic domain LIM PF00412.22 EKX49760.1 - 9.1e-25 86.7 48.1 1.8e-09 37.7 1.0 6.7 4 3 1 5 5 5 5 LIM domain DA1-like PF12315.8 EKX49760.1 - 4.8e-13 49.0 0.1 7.6e-13 48.3 0.1 1.2 1 0 0 1 1 1 1 Protein DA1 SprT-like PF10263.9 EKX49760.1 - 0.12 12.3 0.0 0.36 10.7 0.0 1.9 1 0 0 1 1 1 0 SprT-like family zf-FPG_IleRS PF06827.14 EKX49760.1 - 0.19 11.6 0.1 0.19 11.6 0.1 6.0 7 0 0 7 7 7 0 Zinc finger found in FPG and IleRS DUF4042 PF13251.6 EKX49761.1 - 3.2e-30 105.2 13.1 4.5e-30 104.7 3.1 4.2 6 0 0 6 6 6 2 Domain of unknown function (DUF4042) HEAT_2 PF13646.6 EKX49761.1 - 1.3e-06 28.7 5.9 0.088 13.2 0.1 6.4 5 1 1 6 6 6 2 HEAT repeats HEAT PF02985.22 EKX49761.1 - 2.2e-05 24.3 15.7 0.38 11.1 0.2 7.9 8 0 0 8 8 8 3 HEAT repeat CDT1_C PF16679.5 EKX49761.1 - 2.9 8.4 11.5 14 6.2 0.1 4.5 4 0 0 4 4 4 0 DNA replication factor Cdt1 C-terminal domain WAC_Acf1_DNA_bd PF10537.9 EKX49763.1 - 1.3e-24 86.7 0.6 1.3e-24 86.7 0.6 3.5 2 1 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 EKX49763.1 - 2e-16 60.3 0.0 2e-16 60.3 0.0 3.6 2 1 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 EKX49763.1 - 8.6e-11 42.0 0.0 2e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 DDT domain TAF4 PF05236.14 EKX49763.1 - 0.0049 16.6 26.0 0.014 15.2 15.9 2.7 2 0 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family PIG-S PF10510.9 EKX49763.1 - 0.11 11.4 7.7 0.29 9.9 7.7 1.7 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein AATF-Che1 PF13339.6 EKX49765.1 - 4e-24 85.9 0.1 4e-24 85.9 0.1 3.4 3 2 0 3 3 3 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 EKX49765.1 - 9.5e-21 74.1 2.3 1.2e-20 73.8 0.0 2.4 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal T3SS_needle_E PF08988.10 EKX49765.1 - 0.81 9.9 4.9 8.4 6.6 0.1 3.3 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle Nop14 PF04147.12 EKX49765.1 - 2.9 6.0 47.4 4.6 5.3 41.5 2.2 2 0 0 2 2 2 0 Nop14-like family FAT PF02259.23 EKX49766.1 - 2.3e-37 129.0 6.8 2.3e-37 129.0 6.8 2.6 3 0 0 3 3 3 1 FAT domain PI3_PI4_kinase PF00454.27 EKX49766.1 - 0.00031 20.7 0.0 0.0011 18.9 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ACDC PF14733.6 EKX49766.1 - 0.028 14.7 0.0 12 6.3 0.0 3.6 2 0 0 2 2 2 0 AP2-coincident C-terminal Condensin2nSMC PF12422.8 EKX49766.1 - 0.043 14.0 2.4 6.6 6.9 0.0 4.9 6 0 0 6 6 6 0 Condensin II non structural maintenance of chromosomes subunit DUF5436 PF17504.2 EKX49766.1 - 0.72 10.2 2.6 2.6 8.4 1.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5436) DnaJ_C PF01556.18 EKX49767.1 - 0.0081 16.3 0.3 0.067 13.3 0.3 2.1 1 1 0 1 1 1 1 DnaJ C terminal domain RST PF12174.8 EKX49767.1 - 0.016 15.1 0.1 0.03 14.2 0.1 1.4 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain Glyco_hydro_49N PF17433.2 EKX49767.1 - 0.04 13.5 0.6 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 49 N-terminal Ig-like domain BCDHK_Adom3 PF10436.9 EKX49770.1 - 3.8e-34 117.9 0.0 6.3e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EKX49770.1 - 2.4e-13 50.5 0.0 4.4e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EKX49770.1 - 2.2e-05 24.3 0.0 3.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ArgJ PF01960.18 EKX49770.1 - 0.073 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 ArgJ family Glyco_transf_41 PF13844.6 EKX49771.1 - 6.6e-26 90.8 3.1 2.6e-11 42.6 0.1 3.5 4 0 0 4 4 4 3 Glycosyl transferase family 41 TPR_2 PF07719.17 EKX49771.1 - 3.8e-15 54.7 3.7 0.00014 21.7 0.2 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX49771.1 - 2.9e-13 49.3 0.4 0.0014 18.2 0.0 4.8 4 1 1 5 5 5 4 TPR repeat TPR_8 PF13181.6 EKX49771.1 - 1.1e-12 47.1 0.1 0.053 13.8 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX49771.1 - 7.3e-12 44.6 0.9 0.0068 16.2 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX49771.1 - 1.4e-11 44.0 0.3 0.011 16.1 0.0 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EKX49771.1 - 9.5e-10 38.9 0.1 0.095 13.2 0.0 4.5 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX49771.1 - 2.4e-09 36.8 0.7 0.0044 16.8 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX49771.1 - 3.3e-09 36.9 5.9 0.00044 20.5 0.7 4.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX49771.1 - 5.5e-08 33.3 1.6 0.04 14.6 0.1 4.1 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX49771.1 - 7.2e-05 22.5 1.1 4.3 7.6 0.1 5.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX49771.1 - 0.00063 20.4 3.6 4.3 8.4 0.4 5.5 3 1 3 6 6 6 1 Tetratricopeptide repeat TPR_20 PF14561.6 EKX49771.1 - 0.041 14.2 0.0 5.2 7.5 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TOM20_plant PF06552.12 EKX49771.1 - 0.11 12.2 1.1 17 5.1 0.0 2.7 2 1 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 DUF2723 PF11028.8 EKX49772.1 - 7.3e-33 113.9 4.2 1.7e-32 112.7 4.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2723) PMT_2 PF13231.6 EKX49772.1 - 4.1e-07 30.4 10.7 4.1e-07 30.4 10.7 3.1 3 0 0 3 3 3 2 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF4914 PF16260.5 EKX49772.1 - 0.063 11.4 0.2 0.091 10.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4914) SlyX PF04102.12 EKX49773.1 - 0.092 13.4 3.9 0.38 11.4 3.9 2.2 1 1 1 2 2 2 0 SlyX YjcZ PF13990.6 EKX49773.1 - 0.58 9.5 5.9 1.2 8.5 5.9 1.6 1 1 0 1 1 1 0 YjcZ-like protein Fib_alpha PF08702.10 EKX49773.1 - 1 9.5 5.1 0.82 9.9 3.4 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family CEP19 PF14933.6 EKX49773.1 - 1.1 9.5 9.7 1.4 9.2 9.0 1.4 1 1 0 1 1 1 0 CEP19-like protein NHL PF01436.21 EKX49774.1 - 2.7e-18 65.0 0.4 2.4e-07 30.5 0.0 5.1 5 0 0 5 5 5 4 NHL repeat SGL PF08450.12 EKX49774.1 - 6.8e-07 29.1 0.0 0.00069 19.3 0.0 3.0 1 1 2 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region SBBP PF06739.11 EKX49774.1 - 0.001 19.0 0.0 0.53 10.3 0.0 2.8 3 0 0 3 3 3 2 Beta-propeller repeat DUF839 PF05787.13 EKX49774.1 - 0.0039 16.4 0.0 0.16 11.1 0.0 2.1 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF839) Metallophos PF00149.28 EKX49775.1 - 2.1e-10 41.5 0.0 3.7e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FAM184 PF15665.5 EKX49776.1 - 0.0057 16.5 36.3 0.071 12.9 6.4 3.7 1 1 3 4 4 4 3 Family with sequence similarity 184, A and B Cep57_CLD_2 PF14197.6 EKX49776.1 - 0.012 15.7 36.8 0.015 15.3 11.5 4.7 3 1 2 5 5 5 0 Centrosome localisation domain of PPC89 Cor1 PF04803.12 EKX49776.1 - 0.1 12.8 14.4 0.58 10.4 9.0 2.6 1 1 1 2 2 2 0 Cor1/Xlr/Xmr conserved region MRP-S26 PF14943.6 EKX49776.1 - 0.13 12.2 21.5 0.38 10.7 21.5 1.9 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DsrC PF04358.13 EKX49776.1 - 0.26 11.8 8.6 1.4 9.5 0.8 3.1 1 1 2 3 3 3 0 DsrC like protein DUF572 PF04502.13 EKX49776.1 - 0.3 10.7 14.4 0.56 9.8 14.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) UPF0061 PF02696.14 EKX49776.1 - 0.88 8.3 3.0 1.5 7.5 3.0 1.3 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family TetR_C_24 PF17932.1 EKX49776.1 - 1.4 9.2 22.3 4.3 7.6 3.8 3.4 1 1 2 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DUF148 PF02520.17 EKX49776.1 - 2.5 8.3 11.5 55 3.9 0.2 3.8 1 1 2 3 3 3 0 Domain of unknown function DUF148 Glyco_trans_A_1 PF09318.10 EKX49776.1 - 2.6 7.7 6.5 18 4.9 0.3 2.9 2 1 1 3 3 3 0 Glycosyl transferase 1 domain A ZapB PF06005.12 EKX49776.1 - 3.4 8.2 32.4 0.41 11.1 14.5 2.8 1 1 1 2 2 2 0 Cell division protein ZapB Ax_dynein_light PF10211.9 EKX49776.1 - 3.9 7.4 27.4 0.74 9.7 13.8 2.4 1 1 1 2 2 2 0 Axonemal dynein light chain DUF1759 PF03564.15 EKX49776.1 - 4.6 7.2 10.3 6.2 6.7 2.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) Filament PF00038.21 EKX49776.1 - 6.5 6.2 32.2 2.3 7.7 3.0 2.5 1 1 1 2 2 2 0 Intermediate filament protein DUF3584 PF12128.8 EKX49776.1 - 7 4.0 24.6 9.7 3.6 24.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CSTF_C PF14304.6 EKX49776.1 - 9.5 5.9 11.6 32 4.2 0.2 3.9 1 1 3 5 5 5 0 Transcription termination and cleavage factor C-terminal Ephrin_rec_like PF07699.13 EKX49777.1 - 1.8e-05 24.4 1.6 1.8e-05 24.4 1.6 2.1 2 0 0 2 2 2 1 Putative ephrin-receptor like TB PF00683.17 EKX49777.1 - 0.01 15.6 5.0 0.12 12.2 0.2 2.3 1 1 1 2 2 2 0 TB domain RT_RNaseH_2 PF17919.1 EKX49778.1 - 1.4e-35 121.3 0.0 3.6e-35 120.0 0.0 1.8 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 EKX49778.1 - 3.7e-35 120.4 0.0 4.9e-34 116.8 0.0 2.3 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EKX49778.1 - 2.2e-17 63.3 0.1 4.5e-17 62.3 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 EKX49778.1 - 3.4e-16 59.1 0.3 1.3e-15 57.2 0.1 2.1 2 0 0 2 2 2 1 Integrase zinc binding domain rve PF00665.26 EKX49778.1 - 6.6e-12 45.7 0.0 2.2e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Pox_VLTF3 PF04947.14 EKX49780.1 - 4.1e-47 160.0 9.9 4.9e-47 159.8 9.9 1.0 1 0 0 1 1 1 1 Poxvirus Late Transcription Factor VLTF3 like Gluconate_2-dh3 PF13618.6 EKX49780.1 - 0.079 13.2 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 Phage_int_SAM_4 PF13495.6 EKX49780.1 - 0.082 13.4 1.2 0.17 12.4 1.2 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain HAD_2 PF13419.6 EKX49780.1 - 0.12 12.4 1.3 0.19 11.8 1.3 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase HTH_19 PF12844.7 EKX49780.1 - 0.16 12.0 2.0 19 5.4 0.7 2.9 2 1 0 2 2 2 0 Helix-turn-helix domain Helicase_RecD PF05127.14 EKX49781.1 - 0.065 13.1 0.0 0.071 13.0 0.0 1.0 1 0 0 1 1 1 0 Helicase AAA_10 PF12846.7 EKX49781.1 - 0.074 12.0 0.0 0.076 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain Na_Ca_ex PF01699.24 EKX49783.1 - 4.6e-42 143.5 31.1 1.9e-21 76.6 11.3 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein TPPII_N PF12583.8 EKX49783.1 - 0.2 12.3 0.9 0.48 11.0 0.9 1.6 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Pkinase PF00069.25 EKX49784.1 - 4.9e-58 196.6 0.0 6.9e-58 196.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX49784.1 - 7.5e-33 113.9 0.0 1e-32 113.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX49784.1 - 0.0001 21.8 0.3 0.0002 20.8 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EKX49784.1 - 0.00011 21.3 0.0 0.00015 20.9 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EKX49784.1 - 0.0012 18.8 0.6 0.051 13.5 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EKX49784.1 - 0.003 16.9 0.1 0.0085 15.4 0.0 1.7 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 EKX49784.1 - 0.013 15.1 0.1 0.02 14.5 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 EKX49784.1 - 0.018 13.9 0.1 0.024 13.4 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 EKX49784.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Cornifin PF02389.15 EKX49785.1 - 0.029 14.6 0.1 0.034 14.4 0.1 1.1 1 0 0 1 1 1 0 Cornifin (SPRR) family Titin_Z PF09042.11 EKX49785.1 - 0.05 13.6 0.2 0.05 13.6 0.2 3.7 1 1 5 6 6 6 0 Titin Z UPF0669 PF17065.5 EKX49786.1 - 0.15 11.8 0.0 0.45 10.2 0.0 1.8 2 0 0 2 2 2 0 Putative cytokine, C6ORF120 Bac_rhodopsin PF01036.18 EKX49787.1 - 1.5e-07 31.2 9.3 7.8e-06 25.6 4.6 2.2 1 1 1 2 2 2 2 Bacteriorhodopsin-like protein LysE PF01810.18 EKX49787.1 - 7.9 5.9 9.3 1.3 8.5 1.8 2.5 1 1 0 2 2 2 0 LysE type translocator RIIa PF02197.17 EKX49788.1 - 1.2 8.9 4.8 4.7e+02 0.6 0.0 5.3 6 0 0 6 6 6 0 Regulatory subunit of type II PKA R-subunit Hap4_Hap_bind PF10297.9 EKX49788.1 - 2.9 8.1 27.6 25 5.2 0.6 5.3 5 0 0 5 5 5 0 Minimal binding motif of Hap4 for binding to Hap2/3/5 NAD_binding_10 PF13460.6 EKX49789.1 - 4.3e-28 98.4 0.0 6e-27 94.7 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EKX49789.1 - 1.4e-08 34.6 0.0 4.1e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 EKX49789.1 - 5.1e-06 26.1 0.0 1.2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EKX49789.1 - 1.9e-05 23.8 0.0 2.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EKX49789.1 - 0.012 15.6 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 KR domain DapB_N PF01113.20 EKX49789.1 - 0.029 14.5 0.0 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus GDP_Man_Dehyd PF16363.5 EKX49789.1 - 0.12 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase CK2S PF15011.6 EKX49790.1 - 0.06 13.2 0.0 0.069 13.0 0.0 1.1 1 0 0 1 1 1 0 Casein Kinase 2 substrate RVT_1 PF00078.27 EKX49791.1 - 0.00019 21.0 0.1 0.017 14.6 0.1 2.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) adh_short PF00106.25 EKX49792.1 - 7.6e-23 81.0 0.0 1.5e-18 67.0 0.0 2.5 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EKX49792.1 - 4.6e-14 52.6 0.0 1.1e-11 44.8 0.0 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX49792.1 - 0.00079 19.4 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 KR domain PIF PF05092.12 EKX49792.1 - 0.16 10.6 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 Per os infectivity RhoGAP PF00620.27 EKX49793.1 - 2.6e-17 63.1 0.0 4.7e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Pkinase PF00069.25 EKX49794.1 - 9e-18 64.6 0.2 8.6e-14 51.5 0.0 2.8 1 1 1 2 2 2 2 Protein kinase domain PQQ_2 PF13360.6 EKX49794.1 - 9.4e-15 54.8 0.0 7.6e-09 35.5 0.0 2.8 2 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 EKX49794.1 - 1.8e-11 43.4 0.0 0.00013 21.7 0.0 3.8 3 0 0 3 3 3 3 PQQ enzyme repeat Pkinase_Tyr PF07714.17 EKX49794.1 - 8.3e-09 35.1 0.1 1.4e-05 24.5 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase PQQ_3 PF13570.6 EKX49794.1 - 9.3e-05 22.8 0.4 0.06 13.9 0.0 4.0 4 0 0 4 4 4 1 PQQ-like domain Apt1 PF10351.9 EKX49794.1 - 5.2 5.8 12.2 10 4.9 12.2 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain TPR_MLP1_2 PF07926.12 EKX49795.1 - 0.0011 19.0 2.8 0.0011 19.0 2.8 17.9 8 4 7 16 16 16 4 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 EKX49795.1 - 0.003 17.0 9.3 0.003 17.0 9.3 12.7 2 1 9 11 11 11 3 Domain of unknown function (DUF4407) TINF2_N PF14973.6 EKX49795.1 - 0.011 16.1 1.2 0.011 16.1 1.2 10.3 7 4 1 11 11 11 0 TERF1-interacting nuclear factor 2 N-terminus Pox_A_type_inc PF04508.12 EKX49795.1 - 0.11 12.4 26.2 4.7 7.2 0.1 9.4 9 0 0 9 9 9 0 Viral A-type inclusion protein repeat DUF3974 PF13120.6 EKX49795.1 - 0.41 10.7 4.1 0.24 11.5 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3974) DUF5070 PF16802.5 EKX49795.1 - 2 8.4 6.7 6.6 6.7 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5070) HALZ PF02183.18 EKX49795.1 - 2.2 8.5 0.0 0.076 13.2 1.8 14.4 15 0 0 15 15 15 0 Homeobox associated leucine zipper YvrJ PF12841.7 EKX49795.1 - 7.9 6.1 5.6 32 4.2 0.6 3.9 2 0 0 2 2 2 0 YvrJ protein family PP2C PF00481.21 EKX49796.1 - 3.2e-37 128.6 0.0 4e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EKX49796.1 - 3.7e-05 23.5 4.9 8.7e-05 22.3 3.6 1.9 1 1 1 2 2 2 1 Protein phosphatase 2C Exo_endo_phos PF03372.23 EKX49797.1 - 0.0013 18.3 0.0 0.0015 18.1 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RNA_ligase PF09414.10 EKX49798.1 - 1.9e-31 109.6 0.0 3.4e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 RNA ligase AAA_33 PF13671.6 EKX49798.1 - 4.1e-12 46.5 0.5 1.1e-08 35.4 0.5 2.5 1 1 0 1 1 1 1 AAA domain Y_phosphatase PF00102.27 EKX49798.1 - 3.6e-08 33.3 0.0 7.2e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX49798.1 - 1.3e-07 31.9 0.0 3.3e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EKX49798.1 - 0.00021 21.4 0.0 0.00039 20.5 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family KTI12 PF08433.10 EKX49798.1 - 0.00033 20.2 0.3 0.053 13.0 0.1 2.2 1 1 1 2 2 2 2 Chromatin associated protein KTI12 AAA_22 PF13401.6 EKX49798.1 - 0.0035 17.6 0.0 0.0075 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EKX49798.1 - 0.0061 15.9 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 EKX49798.1 - 0.022 15.2 0.1 0.19 12.1 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain DSPc PF00782.20 EKX49798.1 - 0.031 14.1 0.0 0.08 12.8 0.0 1.6 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain AAA_18 PF13238.6 EKX49798.1 - 0.035 14.6 0.1 0.22 12.1 0.1 2.3 1 1 0 1 1 1 0 AAA domain Y_phosphatase2 PF03162.13 EKX49798.1 - 0.07 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family IstB_IS21 PF01695.17 EKX49798.1 - 0.17 11.6 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein PTPlike_phytase PF14566.6 EKX49799.1 - 4.5e-09 36.6 0.0 8.3e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 EKX49799.1 - 4.8e-09 36.1 0.0 5.3e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EKX49799.1 - 1.9e-05 24.7 0.0 2.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EKX49799.1 - 0.0023 17.7 0.0 0.009 15.8 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 EKX49799.1 - 0.0099 15.5 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.12 EKX49799.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Bromodomain PF00439.25 EKX49800.1 - 3.3e-18 65.5 0.0 4e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Bromodomain PKD_channel PF08016.12 EKX49801.1 - 7.4e-57 192.9 24.1 5.3e-33 114.3 0.3 3.0 2 1 1 3 3 3 2 Polycystin cation channel Ion_trans PF00520.31 EKX49801.1 - 2.6e-09 36.7 22.3 2.6e-09 36.7 22.3 2.2 2 1 0 2 2 2 1 Ion transport protein RHIM PF12721.7 EKX49801.1 - 0.043 14.3 0.1 0.088 13.3 0.1 1.5 1 0 0 1 1 1 0 RIP homotypic interaction motif MAPKK1_Int PF08923.10 EKX49802.1 - 1.7e-11 44.0 0.0 2.9e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting BBL5 PF07289.11 EKX49803.1 - 1.4e-143 478.0 0.0 1.6e-143 477.8 0.0 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein PH_TFIIH PF08567.11 EKX49803.1 - 7.3e-05 23.0 0.0 0.36 11.2 0.0 2.8 2 1 1 3 3 3 2 TFIIH p62 subunit, N-terminal domain Vps36_ESCRT-II PF11605.8 EKX49803.1 - 0.00031 20.9 0.0 0.77 10.0 0.0 2.4 2 0 0 2 2 2 2 Vacuolar protein sorting protein 36 Vps36 Voldacs PF03517.13 EKX49803.1 - 0.00035 20.7 0.2 0.94 9.6 0.0 2.4 2 0 0 2 2 2 2 Regulator of volume decrease after cellular swelling bPH_3 PF14470.6 EKX49803.1 - 0.00073 19.8 0.2 0.0072 16.7 0.0 2.2 2 0 0 2 2 2 1 Bacterial PH domain ATG16 PF08614.11 EKX49804.1 - 0.0098 16.1 16.1 0.0098 16.1 16.1 7.5 1 1 5 7 7 7 3 Autophagy protein 16 (ATG16) RWP-RK PF02042.15 EKX49804.1 - 0.057 13.4 0.0 0.2 11.6 0.0 2.0 1 0 0 1 1 1 0 RWP-RK domain Gln_amidase PF15644.6 EKX49804.1 - 0.29 12.2 5.1 9.5 7.3 0.7 4.0 3 0 0 3 3 3 0 Papain fold toxin 1, glutamine deamidase FmiP_Thoc5 PF09766.9 EKX49805.1 - 1.5e-56 192.3 1.0 2.5e-56 191.5 1.0 1.4 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 PelG PF16933.5 EKX49805.1 - 0.025 13.4 7.8 0.038 12.8 7.8 1.2 1 0 0 1 1 1 0 Putative exopolysaccharide Exporter (EPS-E) SPP PF06550.11 EKX49805.1 - 0.085 12.3 6.1 0.12 11.8 6.1 1.1 1 0 0 1 1 1 0 Signal-peptide peptidase, presenilin aspartyl protease IATP PF04568.12 EKX49805.1 - 1.7 9.1 7.3 6.9 7.2 2.4 2.6 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP DUF4407 PF14362.6 EKX49805.1 - 5.5 6.2 5.9 36 3.6 5.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MCM_OB PF17207.3 EKX49806.1 - 5.5e-13 48.9 1.7 6.2e-13 48.7 1.7 1.0 1 0 0 1 1 1 1 MCM OB domain zf-RRN7 PF11781.8 EKX49806.1 - 0.078 12.7 4.9 0.63 9.8 0.2 2.8 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Sec6 PF06046.13 EKX49807.1 - 3.6e-72 243.6 0.1 5.5e-72 243.0 0.1 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 HTH_Mga PF08280.11 EKX49807.1 - 0.0087 16.1 0.9 0.023 14.7 0.9 1.8 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain MutS_III PF05192.18 EKX49807.1 - 0.083 13.1 0.0 0.42 10.8 0.0 2.2 1 1 0 1 1 1 0 MutS domain III cwf21 PF08312.12 EKX49807.1 - 0.12 12.6 0.8 1.4 9.2 0.0 3.2 3 1 0 3 3 3 0 cwf21 domain CUB PF00431.20 EKX49808.1 - 0.063 13.6 0.0 0.068 13.5 0.0 1.1 1 0 0 1 1 1 0 CUB domain DUF4064 PF13273.6 EKX49809.1 - 0.064 13.5 4.3 0.74 10.1 0.6 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) OSTbeta PF15048.6 EKX49809.1 - 0.11 12.7 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Phage_holin_3_6 PF07332.11 EKX49809.1 - 1 9.4 6.0 9 6.4 2.0 2.9 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III CAC1F_C PF16885.5 EKX49810.1 - 0.11 12.2 2.5 0.11 12.1 2.5 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term PAC1 PF16094.5 EKX49810.1 - 0.16 11.1 3.9 0.19 10.9 3.9 1.1 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 PBP1_TM PF14812.6 EKX49810.1 - 0.4 11.1 2.3 0.61 10.5 2.3 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TssO PF17561.2 EKX49810.1 - 0.74 9.9 6.0 1.1 9.4 6.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssO Cwf_Cwc_15 PF04889.12 EKX49810.1 - 0.94 9.2 9.0 1.4 8.6 9.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Myc_N PF01056.18 EKX49810.1 - 1.2 9.0 6.4 1.4 8.7 6.4 1.1 1 0 0 1 1 1 0 Myc amino-terminal region TrbL PF04610.14 EKX49811.1 - 0.0047 16.7 0.8 0.0069 16.2 0.8 1.2 1 0 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein EI24 PF07264.11 EKX49811.1 - 0.0068 16.7 0.0 0.01 16.1 0.0 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF444 PF04285.12 EKX49811.1 - 0.06 12.4 7.6 0.11 11.6 7.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF444) PepSY_TM PF03929.16 EKX49811.1 - 0.22 11.2 0.4 0.69 9.5 0.0 2.0 1 1 1 2 2 2 0 PepSY-associated TM region Shisa PF13908.6 EKX49811.1 - 2 8.6 6.8 1.3 9.2 0.3 2.6 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Synaptobrevin PF00957.21 EKX49811.1 - 2.6 7.9 3.9 10 6.0 1.0 2.4 2 0 0 2 2 2 0 Synaptobrevin Connexin PF00029.19 EKX49812.1 - 0.077 12.7 2.5 0.084 12.6 2.5 1.1 1 0 0 1 1 1 0 Connexin Nop14 PF04147.12 EKX49812.1 - 0.086 11.1 25.8 0.091 11.0 25.8 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EKX49812.1 - 0.099 12.1 26.8 0.11 11.9 26.8 1.0 1 0 0 1 1 1 0 SDA1 Tim54 PF11711.8 EKX49812.1 - 0.16 10.7 7.8 0.18 10.6 7.8 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.12 EKX49812.1 - 0.19 11.5 9.1 0.21 11.4 9.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Striatin PF08232.12 EKX49812.1 - 0.22 12.1 6.9 0.23 12.0 6.9 1.1 1 0 0 1 1 1 0 Striatin family PTPRCAP PF15713.5 EKX49812.1 - 0.34 11.2 15.5 0.39 11.0 15.5 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CPSF100_C PF13299.6 EKX49812.1 - 0.43 10.7 7.6 0.51 10.5 7.6 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RNA_pol_Rpc4 PF05132.14 EKX49812.1 - 0.45 10.9 10.4 0.54 10.7 10.4 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 SpoIIP PF07454.11 EKX49812.1 - 0.47 9.9 8.3 0.48 9.8 8.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Vfa1 PF08432.10 EKX49812.1 - 0.56 10.5 18.7 0.87 9.9 18.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF913 PF06025.12 EKX49812.1 - 0.6 9.0 5.2 0.59 9.0 5.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 EKX49812.1 - 0.91 8.7 6.6 1 8.5 6.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DNA_pol_phi PF04931.13 EKX49812.1 - 1.3 7.0 31.8 1.5 6.8 31.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 EKX49812.1 - 1.4 7.1 24.5 1.5 7.0 24.5 1.0 1 0 0 1 1 1 0 CDC45-like protein PI3K_1B_p101 PF10486.9 EKX49812.1 - 2.3 5.9 7.4 2.9 5.5 7.4 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF2151 PF10221.9 EKX49812.1 - 2.3 6.7 8.3 2.3 6.7 8.3 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator CobT PF06213.12 EKX49812.1 - 2.4 7.5 22.8 2.8 7.2 22.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PDCD2_C PF04194.13 EKX49812.1 - 2.5 8.1 10.3 2.9 7.9 10.3 1.2 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain SAPS PF04499.15 EKX49812.1 - 3 6.5 12.7 3.2 6.4 12.7 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GEN1_C PF18380.1 EKX49812.1 - 3.2 8.7 13.0 4.6 8.2 13.0 1.3 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain RNA_polI_A34 PF08208.11 EKX49812.1 - 3.5 7.7 25.0 4.3 7.4 25.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Presenilin PF01080.17 EKX49812.1 - 3.6 6.3 6.3 4 6.1 6.3 1.0 1 0 0 1 1 1 0 Presenilin tRNA_bind_2 PF13725.6 EKX49812.1 - 4.3 7.0 11.5 4.8 6.8 11.5 1.0 1 0 0 1 1 1 0 Possible tRNA binding domain TRAP_alpha PF03896.16 EKX49812.1 - 8.8 5.4 14.9 11 5.2 14.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pkinase PF00069.25 EKX49814.1 - 7.1e-29 101.0 0.1 1.3e-28 100.1 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX49814.1 - 1.9e-17 63.4 0.3 3.2e-17 62.7 0.3 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase U-box PF04564.15 EKX49814.1 - 1.3e-10 41.3 0.0 3.1e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX49814.1 - 0.096 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit ABC_membrane PF00664.23 EKX49816.1 - 1.4e-67 228.2 8.0 9.6e-36 123.8 0.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EKX49816.1 - 1.5e-32 112.9 0.3 5.5e-22 78.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 EKX49816.1 - 1.8e-07 31.2 0.1 0.0023 17.8 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EKX49816.1 - 1.1e-06 28.2 0.2 0.049 13.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EKX49816.1 - 1.5e-06 28.2 2.0 0.019 15.0 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EKX49816.1 - 3.7e-06 27.6 8.0 0.062 13.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.19 EKX49816.1 - 1.3e-05 24.7 1.7 0.11 11.9 0.1 3.3 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EKX49816.1 - 0.00011 22.1 3.4 0.086 12.6 0.2 3.4 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EKX49816.1 - 0.00024 21.4 1.1 0.14 12.4 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EKX49816.1 - 0.00044 20.7 2.2 0.085 13.2 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain DUF87 PF01935.17 EKX49816.1 - 0.00079 19.6 0.4 0.74 9.9 0.1 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain NB-ARC PF00931.22 EKX49816.1 - 0.00085 18.6 0.4 0.26 10.4 0.0 3.2 2 1 0 2 2 2 1 NB-ARC domain MeaB PF03308.16 EKX49816.1 - 0.0011 18.0 0.3 0.13 11.2 0.1 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB T2SSE PF00437.20 EKX49816.1 - 0.014 14.5 0.0 0.15 11.1 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA PF00004.29 EKX49816.1 - 0.021 15.2 1.6 0.13 12.7 0.1 2.7 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 EKX49816.1 - 0.023 14.8 7.4 1.1 9.4 0.8 3.2 3 0 0 3 3 3 0 Dynamin family Rad17 PF03215.15 EKX49816.1 - 0.024 14.6 0.5 0.076 12.9 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain TsaE PF02367.17 EKX49816.1 - 0.028 14.4 0.1 0.85 9.6 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_15 PF13175.6 EKX49816.1 - 0.029 14.1 2.6 0.4 10.3 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.22 EKX49816.1 - 0.04 14.3 0.3 6.5 7.2 0.0 2.9 3 0 0 3 3 2 0 RNA helicase DUF4604 PF15377.6 EKX49816.1 - 0.049 14.0 5.5 0.091 13.2 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) AAA_7 PF12775.7 EKX49816.1 - 0.071 12.6 0.2 12 5.4 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 EKX49816.1 - 0.078 12.6 1.7 1.4 8.5 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FancD2 PF14631.6 EKX49816.1 - 0.1 10.0 0.2 0.15 9.5 0.2 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease AAA_25 PF13481.6 EKX49816.1 - 0.11 12.1 0.1 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Spore_IV_A PF09547.10 EKX49816.1 - 0.14 11.1 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) Zeta_toxin PF06414.12 EKX49816.1 - 0.14 11.4 0.1 5.7 6.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 EKX49816.1 - 0.14 12.3 1.1 2.2 8.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain WSS_VP PF12175.8 EKX49816.1 - 0.16 11.4 0.0 0.88 9.0 0.0 2.0 2 0 0 2 2 2 0 White spot syndrome virus structural envelope protein VP GTP_EFTU PF00009.27 EKX49816.1 - 0.17 11.4 0.0 5.4 6.5 0.1 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain IstB_IS21 PF01695.17 EKX49816.1 - 0.18 11.5 0.4 15 5.2 0.1 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 EKX49816.1 - 0.22 11.4 1.1 2.5 8.0 0.3 2.6 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 EKX49816.1 - 0.26 11.8 4.4 7.4 7.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF4695 PF15766.5 EKX49816.1 - 3.6 7.8 8.5 10 6.4 8.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4695) His_Phos_1 PF00300.22 EKX49818.1 - 1.7e-20 73.5 0.0 1.2e-13 51.2 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Tmemb_9 PF05434.11 EKX49819.1 - 0.064 13.1 0.0 0.082 12.8 0.0 1.2 1 1 0 1 1 1 0 TMEM9 DUF3377 PF11857.8 EKX49819.1 - 0.55 10.2 2.1 1.2 9.1 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DnaJ PF00226.31 EKX49820.1 - 1.7e-25 88.9 1.1 2.2e-25 88.5 1.1 1.1 1 0 0 1 1 1 1 DnaJ domain RRM_7 PF16367.5 EKX49820.1 - 0.12 12.5 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif BCCT PF02028.17 EKX49821.1 - 2e-33 115.6 22.4 6.1e-30 104.1 14.4 2.0 1 1 1 2 2 2 2 BCCT, betaine/carnitine/choline family transporter PKD_3 PF16820.5 EKX49822.1 - 0.15 11.9 0.0 6 6.7 0.0 2.2 2 0 0 2 2 2 0 PKD-like domain Ank_4 PF13637.6 EKX49823.1 - 8.6e-29 99.5 10.9 2.2e-10 40.9 0.2 5.1 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX49823.1 - 2.8e-20 72.7 3.1 9.6e-10 38.9 0.9 3.6 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX49823.1 - 8.6e-19 67.4 3.6 1.1e-05 25.7 0.1 5.0 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EKX49823.1 - 1.5e-15 56.8 7.0 2.1e-05 24.7 0.1 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 EKX49823.1 - 1.3e-14 52.9 2.1 0.00015 21.9 0.1 5.8 6 0 0 6 6 6 3 Ankyrin repeat HTH_23 PF13384.6 EKX49824.1 - 0.028 14.2 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain KorB PF08535.10 EKX49824.1 - 0.1 12.6 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 KorB domain Sigma70_r4 PF04545.16 EKX49824.1 - 0.12 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 CENP-B_N PF04218.13 EKX49824.1 - 0.14 11.9 0.8 0.45 10.2 0.5 1.9 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 EKX49825.1 - 0.028 14.2 0.0 0.053 13.3 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain KorB PF08535.10 EKX49825.1 - 0.1 12.6 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 KorB domain Sigma70_r4 PF04545.16 EKX49825.1 - 0.12 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 CENP-B_N PF04218.13 EKX49825.1 - 0.13 11.9 0.8 0.45 10.2 0.5 2.0 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Fer4_8 PF13183.6 EKX49825.1 - 2 8.9 8.7 0.78 10.2 5.7 2.0 1 1 0 2 2 2 0 4Fe-4S dicluster domain ParcG PF10274.9 EKX49826.1 - 5.7e-83 277.5 0.0 7.3e-83 277.2 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein DCB PF16213.5 EKX49826.1 - 0.083 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 Ion_trans PF00520.31 EKX49828.1 - 2.9e-31 108.6 20.1 3.6e-31 108.2 20.1 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EKX49828.1 - 1.5e-05 23.8 11.0 1.5e-05 23.8 11.0 2.1 1 1 1 2 2 2 1 Polycystin cation channel FMN_red PF03358.15 EKX49828.1 - 0.016 15.0 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 NADPH-dependent FMN reductase Myosin_TH1 PF06017.13 EKX49828.1 - 0.025 14.3 0.7 1.3 8.7 0.0 2.6 3 0 0 3 3 3 0 Unconventional myosin tail, actin- and lipid-binding HATPase_c_5 PF14501.6 EKX49828.1 - 0.034 14.1 0.4 3.8 7.5 0.0 2.5 2 0 0 2 2 2 0 GHKL domain PH PF00169.29 EKX49828.1 - 0.091 13.3 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 PH domain CENP-B_dimeris PF09026.10 EKX49829.1 - 0.015 15.7 5.1 0.015 15.7 5.1 1.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Voldacs PF03517.13 EKX49829.1 - 0.067 13.3 5.1 0.081 13.0 5.1 1.1 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling GOLD_2 PF13897.6 EKX49829.1 - 0.35 11.3 3.4 0.31 11.5 2.4 1.5 1 1 0 1 1 1 0 Golgi-dynamics membrane-trafficking DNA_pol_phi PF04931.13 EKX49829.1 - 0.64 8.1 6.3 0.58 8.2 6.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 EKX49829.1 - 9.1 4.3 13.7 11 4.1 13.7 1.0 1 0 0 1 1 1 0 Nop14-like family SET PF00856.28 EKX49830.1 - 6.2e-09 36.5 0.0 1.9e-08 34.9 0.0 1.8 1 1 0 1 1 1 1 SET domain Wzy_C PF04932.15 EKX49830.1 - 0.0026 17.4 4.0 0.0037 16.9 4.0 1.2 1 0 0 1 1 1 1 O-Antigen ligase Pex24p PF06398.11 EKX49830.1 - 0.26 10.2 2.0 0.33 9.9 2.0 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Histone PF00125.24 EKX49831.1 - 1.1e-51 174.6 1.4 1.2e-51 174.5 1.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EKX49831.1 - 0.00013 22.0 0.1 0.00025 21.1 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EKX49831.1 - 0.00022 21.8 0.8 0.00026 21.6 0.8 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 EKX49831.1 - 0.00089 19.6 0.0 0.0014 19.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein Sirohm_synth_M PF14824.6 EKX49831.1 - 0.5 9.9 2.2 2.9 7.4 0.2 2.5 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central Kelch_4 PF13418.6 EKX49832.1 - 1.4e-40 137.1 0.2 3.3e-10 39.8 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 EKX49832.1 - 9.3e-37 124.4 1.7 1.1e-06 28.1 0.0 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 EKX49832.1 - 1.5e-36 123.8 0.1 0.00022 21.1 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 EKX49832.1 - 2.5e-32 110.1 0.0 4e-07 30.1 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EKX49832.1 - 4.6e-32 109.7 2.9 2.6e-07 30.7 0.0 6.6 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_2 PF07646.15 EKX49832.1 - 7.7e-28 95.4 2.3 9.9e-05 22.2 0.1 6.4 6 0 0 6 6 6 6 Kelch motif ACBP PF00887.19 EKX49832.1 - 1.7e-06 28.1 0.0 4.3e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Acyl CoA binding protein Pkinase_Tyr PF07714.17 EKX49833.1 - 1.4e-50 172.0 0.0 1.7e-50 171.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX49833.1 - 4.3e-49 167.3 0.0 5.3e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EKX49833.1 - 0.0024 16.7 0.0 0.003 16.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX49833.1 - 0.017 15.1 0.0 0.041 13.8 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Peptidase_S9 PF00326.21 EKX49834.1 - 1.1e-49 168.8 0.1 1.8e-49 168.1 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 EKX49834.1 - 1.4e-16 60.3 0.1 1.1e-15 57.3 0.1 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Hydrolase_4 PF12146.8 EKX49834.1 - 3.8e-05 23.1 0.1 0.0014 17.9 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Trypsin PF00089.26 EKX49835.1 - 1.4e-28 100.3 0.9 2.2e-28 99.6 0.9 1.4 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 EKX49835.1 - 5.6e-05 24.1 0.0 0.00011 23.1 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain Hom_end_hint PF05203.16 EKX49836.1 - 0.016 15.2 0.6 0.034 14.1 0.6 1.5 1 0 0 1 1 1 0 Hom_end-associated Hint DUF4653 PF15546.6 EKX49836.1 - 2.5 7.7 6.6 11 5.6 6.3 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4653) PrmA PF06325.13 EKX49837.1 - 6e-11 42.3 0.0 8.9e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EKX49837.1 - 3.3e-08 34.1 0.0 1.1e-07 32.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX49837.1 - 3.4e-08 34.1 0.0 6.5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EKX49837.1 - 2.4e-07 30.3 0.0 3.8e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EKX49837.1 - 4.7e-07 29.5 0.0 8.1e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PRMT5 PF05185.16 EKX49837.1 - 3.4e-06 27.0 0.1 8.3e-06 25.8 0.1 1.6 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.6 EKX49837.1 - 6.3e-06 26.1 0.0 9.3e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX49837.1 - 0.00012 21.9 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EKX49837.1 - 0.0013 18.5 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.7 EKX49837.1 - 0.0031 17.5 0.0 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EKX49837.1 - 0.0063 16.3 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 EKX49837.1 - 0.028 14.1 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_12 PF08242.12 EKX49837.1 - 0.029 15.1 0.0 0.056 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 EKX49837.1 - 0.077 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) GidB PF02527.15 EKX49837.1 - 0.08 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Ubie_methyltran PF01209.18 EKX49837.1 - 0.083 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family GCD14 PF08704.10 EKX49837.1 - 0.096 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Na_Ca_ex PF01699.24 EKX49840.1 - 1.8e-30 105.9 20.2 2e-30 105.8 19.3 1.5 2 0 0 2 2 2 1 Sodium/calcium exchanger protein EF-hand_7 PF13499.6 EKX49840.1 - 3.7e-06 27.3 1.5 0.023 15.1 0.5 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EKX49840.1 - 0.00046 20.0 2.8 0.063 13.1 0.1 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX49840.1 - 0.0064 16.3 1.5 28 5.0 0.0 3.4 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 EKX49840.1 - 0.087 12.4 0.3 8.8 6.1 0.0 2.8 3 0 0 3 3 3 0 EF hand DUF2070 PF09843.9 EKX49840.1 - 0.86 7.8 10.1 1.3 7.3 10.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ESSS PF10183.9 EKX49840.1 - 1.2 9.4 3.6 2.6 8.3 3.6 1.5 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) VKOR PF07884.14 EKX49840.1 - 2 8.6 13.9 0.73 10.0 1.3 2.4 2 0 0 2 2 2 0 Vitamin K epoxide reductase family Metallophos PF00149.28 EKX49841.1 - 9.8e-18 65.4 0.5 1.4e-17 64.9 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EKX49841.1 - 0.0048 17.1 1.1 0.097 12.9 1.1 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF89 PF01937.19 EKX49842.1 - 2.1e-55 188.1 0.0 2.4e-53 181.4 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function DUF89 RHSP PF07999.11 EKX49843.1 - 0.015 14.2 0.0 0.024 13.4 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon hot spot protein C12orf66_like PF09404.10 EKX49843.1 - 0.052 12.4 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 KICSTOR complex C12orf66 like Gloverin PF10793.9 EKX49843.1 - 0.087 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Gloverin-like protein RNA_helicase PF00910.22 EKX49843.1 - 0.15 12.4 0.0 0.67 10.4 0.0 2.1 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 EKX49843.1 - 0.38 10.1 0.0 0.38 10.1 0.0 3.1 4 0 0 4 4 4 0 KaiC DUF2968 PF11180.8 EKX49843.1 - 2.1 7.9 11.4 0.76 9.4 8.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) RWP-RK PF02042.15 EKX49844.1 - 1.7e-13 50.3 0.0 6.5e-13 48.4 0.0 1.9 2 0 0 2 2 2 1 RWP-RK domain RWP-RK PF02042.15 EKX49845.1 - 3.4e-13 49.4 0.0 5.5e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain GST_C_3 PF14497.6 EKX49846.1 - 1.7e-13 50.6 0.0 2.7e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EKX49846.1 - 2.7e-10 40.3 0.0 4.4e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EKX49846.1 - 3.1e-08 33.5 0.0 5.7e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EKX49846.1 - 6.6e-07 29.6 0.0 1.1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EKX49846.1 - 0.00039 20.8 0.0 0.002 18.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 EKX49846.1 - 0.0014 18.4 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EKX49846.1 - 0.0073 16.6 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF2723 PF11028.8 EKX49847.1 - 5.5e-09 36.2 0.3 5.5e-09 36.2 0.3 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2723) PMT_2 PF13231.6 EKX49847.1 - 9.2 6.5 12.0 0.097 12.9 0.7 2.8 3 0 0 3 3 3 0 Dolichyl-phosphate-mannose-protein mannosyltransferase ADP_ribosyl_GH PF03747.14 EKX49848.1 - 7.6e-22 78.4 0.0 1.2e-21 77.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase CIAPIN1 PF05093.13 EKX49849.1 - 1.2e-17 64.2 19.0 9.3e-17 61.4 16.0 2.8 1 1 1 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 EKX49849.1 - 0.035 14.4 0.0 0.051 13.8 0.0 1.3 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus Ribosomal_L27e PF01777.18 EKX49850.1 - 8.7e-34 115.7 5.5 1.1e-33 115.4 5.5 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EKX49850.1 - 8.7e-05 22.3 2.4 0.00018 21.3 2.4 1.6 1 0 0 1 1 1 1 KOW motif Thioredoxin_15 PF18403.1 EKX49850.1 - 0.14 12.0 0.1 18 5.2 0.1 2.7 3 0 0 3 3 3 0 Thioredoxin-like domain Hydrolase_4 PF12146.8 EKX49851.1 - 4.7e-16 58.8 0.0 5.1e-09 35.8 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EKX49851.1 - 2.1e-14 53.8 0.0 3.9e-08 33.3 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EKX49851.1 - 2.4e-09 37.0 0.0 1.3e-08 34.6 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EKX49851.1 - 5.3e-07 30.5 0.0 0.00042 21.0 0.0 2.7 1 1 2 3 3 3 2 Alpha/beta hydrolase family DLH PF01738.18 EKX49851.1 - 1.1e-06 28.4 0.0 0.0001 21.9 0.0 3.0 2 2 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.12 EKX49851.1 - 2.7e-06 26.3 0.1 0.00093 18.0 0.0 2.8 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 EKX49851.1 - 5.3e-06 26.5 0.0 0.0043 17.0 0.0 2.2 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 EKX49851.1 - 8.1e-06 25.6 0.0 2.7e-05 23.9 0.0 1.8 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EKX49851.1 - 4.7e-05 23.3 0.0 0.024 14.4 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 EKX49851.1 - 0.0079 16.0 0.0 0.37 10.5 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 EKX49851.1 - 0.012 15.3 0.1 4 7.0 0.0 2.6 3 0 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 EKX49851.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF818 PF05677.12 EKX49851.1 - 0.12 11.4 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Esterase PF00756.20 EKX49851.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase PDZ_6 PF17820.1 EKX49852.1 - 7.7e-06 25.7 0.2 2.2e-05 24.2 0.2 1.9 1 1 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX49852.1 - 0.00031 21.0 0.0 0.00093 19.5 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX49852.1 - 0.00078 19.8 0.0 0.0019 18.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Cauli_AT PF03233.13 EKX49852.1 - 1.4 8.8 5.5 0.96 9.4 0.2 3.0 2 1 0 2 2 2 0 Aphid transmission protein LPP PF04728.13 EKX49852.1 - 3.6 8.1 6.8 2.7 8.4 0.0 3.3 2 1 1 3 3 3 0 Lipoprotein leucine-zipper Pinin_SDK_memA PF04696.13 EKX49853.1 - 2.9e-20 72.7 23.8 2.9e-20 72.7 23.8 4.1 2 1 2 4 4 4 1 pinin/SDK/memA/ protein conserved region Vir_act_alpha_C PF10400.9 EKX49853.1 - 2.5 8.9 13.6 1.8 9.3 6.6 3.3 3 0 0 3 3 3 0 Virulence activator alpha C-term Aida_C2 PF14186.6 EKX49854.1 - 4.1e-45 153.0 0.5 6.8e-45 152.3 0.5 1.3 1 0 0 1 1 1 1 Cytoskeletal adhesion Aida_N PF08910.10 EKX49854.1 - 2.4e-05 24.7 0.7 4.9e-05 23.6 0.7 1.5 1 0 0 1 1 1 1 Aida N-terminus Med20 PF08612.11 EKX49854.1 - 0.035 13.5 0.1 0.057 12.8 0.1 1.2 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Yuri_gagarin PF15934.5 EKX49854.1 - 0.048 13.5 0.9 0.078 12.8 0.9 1.2 1 0 0 1 1 1 0 Yuri gagarin KASH_CCD PF14662.6 EKX49856.1 - 0.013 15.4 60.9 0.026 14.3 22.8 4.5 2 1 3 5 5 5 0 Coiled-coil region of CCDC155 or KASH Sec2p PF06428.11 EKX49856.1 - 0.024 14.6 57.8 0.86 9.6 5.7 7.1 2 1 5 7 7 7 0 GDP/GTP exchange factor Sec2p S_100 PF01023.19 EKX49856.1 - 0.18 11.5 15.2 6.7 6.5 0.3 4.4 4 0 0 4 4 4 0 S-100/ICaBP type calcium binding domain DUF5101 PF17031.5 EKX49856.1 - 2.3 8.4 48.0 1.8 8.7 5.4 5.6 2 2 4 6 6 6 0 Domain of unknown function (DUF5101) FAM76 PF16046.5 EKX49856.1 - 3 7.1 56.2 1.9 7.7 16.6 4.4 1 1 4 5 5 5 0 FAM76 protein Blt1_C PF17183.4 EKX49856.1 - 3.5 7.3 6.9 73 3.1 0.1 3.7 3 1 0 3 3 3 0 Get5 carboxyl domain Prominin PF05478.11 EKX49856.1 - 4.9 5.0 25.1 11 3.8 16.3 2.5 1 1 2 3 3 3 0 Prominin E7 PF00527.18 EKX49861.1 - 0.29 11.4 4.2 0.28 11.4 0.8 2.4 1 1 1 2 2 2 0 E7 protein, Early protein DDE_Tnp_4 PF13359.6 EKX49862.1 - 2.6e-08 33.7 0.0 3e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Sushi PF00084.20 EKX49863.1 - 1.1e-34 118.7 118.5 0.0032 18.0 0.4 24.0 22 3 1 23 23 23 19 Sushi repeat (SCR repeat) FYVE PF01363.21 EKX49864.1 - 2.6e-06 27.5 0.6 0.0018 18.4 0.4 2.9 2 1 0 2 2 2 2 FYVE zinc finger TRAPP PF04051.16 EKX49864.1 - 0.085 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Transport protein particle (TRAPP) component Aerolysin PF01117.20 EKX49864.1 - 0.11 11.7 1.4 0.13 11.4 0.1 1.7 2 0 0 2 2 2 0 Aerolysin toxin Dicistro_VP4 PF11492.8 EKX49865.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Cricket paralysis virus, VP4 Troponin PF00992.20 EKX49865.1 - 0.2 12.0 5.0 0.35 11.2 5.0 1.3 1 0 0 1 1 1 0 Troponin TAF8_C PF10406.9 EKX49866.1 - 0.021 15.4 0.1 0.086 13.4 0.1 2.0 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term CFTR_R PF14396.6 EKX49866.1 - 2.9 7.4 9.0 0.46 10.0 3.5 2.2 2 0 0 2 2 2 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain PUL PF08324.11 EKX49868.1 - 1.2e-37 129.7 0.9 1.7e-37 129.2 0.9 1.2 1 0 0 1 1 1 1 PUL domain WD40 PF00400.32 EKX49868.1 - 4e-34 116.1 33.2 2.7e-07 31.2 0.2 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat PFU PF09070.11 EKX49868.1 - 7.9e-31 106.7 0.4 1.8e-30 105.5 0.4 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) BBS2_Mid PF14783.6 EKX49868.1 - 0.0016 18.4 0.0 0.5 10.4 0.0 3.2 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 EKX49868.1 - 0.086 11.5 0.4 0.27 9.8 0.1 1.9 2 0 0 2 2 2 0 Nucleoporin Nup120/160 WW PF00397.26 EKX49869.1 - 5.5e-09 36.0 12.7 4e-05 23.6 1.0 4.2 4 0 0 4 4 4 3 WW domain FF PF01846.19 EKX49869.1 - 4.1e-07 30.1 0.2 4.1e-07 30.1 0.2 2.6 3 0 0 3 3 3 1 FF domain PRP38_assoc PF12871.7 EKX49869.1 - 0.00067 20.2 39.2 0.0025 18.4 39.2 2.0 1 0 0 1 1 1 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term ABC1 PF03109.16 EKX49870.1 - 1.6e-35 121.9 0.0 4e-35 120.5 0.0 1.7 2 0 0 2 2 2 1 ABC1 family RIO1 PF01163.22 EKX49870.1 - 6.2e-06 25.9 0.1 0.00013 21.6 0.1 2.2 1 1 0 1 1 1 1 RIO1 family Pkinase PF00069.25 EKX49870.1 - 1.5e-05 24.5 0.0 0.00053 19.4 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 EKX49870.1 - 2e-05 24.6 1.2 0.0019 18.2 0.1 3.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.11 EKX49870.1 - 0.0008 19.1 0.0 0.0021 17.7 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) mRNA_decap_C PF16741.5 EKX49870.1 - 0.11 11.8 0.6 0.78 9.1 0.0 2.6 3 0 0 3 3 3 0 mRNA-decapping enzyme C-terminus LRR_6 PF13516.6 EKX49871.1 - 2.7e-11 42.6 3.1 1.3 9.3 0.1 6.0 7 0 0 7 7 7 5 Leucine Rich repeat LRR_4 PF12799.7 EKX49871.1 - 2.3e-09 37.4 1.1 0.025 15.0 0.0 5.1 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX49871.1 - 7.8e-05 22.7 4.0 11 7.0 0.0 6.3 5 1 0 5 5 5 1 Leucine Rich Repeat SAM_Ste50p PF09235.10 EKX49871.1 - 2.5 8.4 5.2 71 3.7 0.2 3.7 2 1 1 4 4 4 0 Ste50p, sterile alpha motif RNase_PH PF01138.21 EKX49872.1 - 5e-29 101.5 1.0 6.9e-29 101.0 0.3 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EKX49872.1 - 3.7e-05 23.7 0.0 8.4e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF3135 PF11333.8 EKX49872.1 - 0.31 11.3 0.9 6.1 7.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3135) Pkinase PF00069.25 EKX49873.1 - 1.3e-46 159.1 1.7 1.6e-45 155.5 1.7 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX49873.1 - 1.5e-19 70.4 1.1 1.7e-18 66.8 1.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX49873.1 - 0.00066 19.7 0.8 0.0028 17.6 0.2 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EKX49873.1 - 0.0025 17.4 1.2 0.0071 16.0 1.2 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase FHA PF00498.26 EKX49873.1 - 0.32 11.4 2.4 4 7.9 0.4 3.1 1 1 1 2 2 2 0 FHA domain VPS9 PF02204.18 EKX49874.1 - 4.8e-24 84.6 0.1 8e-24 83.8 0.1 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ser_hydrolase PF06821.13 EKX49876.1 - 8.6e-11 42.0 0.0 1.1e-10 41.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_1 PF00561.20 EKX49876.1 - 0.00042 20.1 0.0 0.0013 18.5 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EKX49876.1 - 0.004 16.4 0.0 0.01 15.2 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EKX49876.1 - 0.0069 17.0 0.0 0.0098 16.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.12 EKX49876.1 - 0.008 15.2 0.1 0.025 13.6 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) DUF3089 PF11288.8 EKX49876.1 - 0.031 13.8 0.0 0.05 13.2 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3089) DUF1151 PF06625.11 EKX49876.1 - 0.15 12.0 0.0 0.79 9.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) Abhydrolase_5 PF12695.7 EKX49876.1 - 0.17 11.7 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family AAA PF00004.29 EKX49880.1 - 6.6e-38 130.1 0.3 1.9e-37 128.7 0.0 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EKX49880.1 - 4.2e-19 68.2 0.3 8.6e-19 67.2 0.3 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EKX49880.1 - 1e-09 38.0 0.2 2.4e-09 36.9 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EKX49880.1 - 4.1e-06 27.0 0.0 1.9e-05 24.8 0.0 2.0 1 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EKX49880.1 - 2.1e-05 24.5 1.2 0.00012 22.1 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EKX49880.1 - 0.00018 21.9 0.1 0.0019 18.6 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EKX49880.1 - 0.00098 18.9 0.0 0.0029 17.3 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EKX49880.1 - 0.0032 17.7 0.6 0.075 13.3 0.6 2.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EKX49880.1 - 0.0053 16.2 0.0 0.075 12.5 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein ATPase PF06745.13 EKX49880.1 - 0.0082 15.5 0.9 0.056 12.8 0.0 2.2 2 0 0 2 2 2 1 KaiC Mg_chelatase PF01078.21 EKX49880.1 - 0.021 14.2 0.0 0.052 12.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EKX49880.1 - 0.024 14.8 0.0 0.085 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EKX49880.1 - 0.026 14.3 0.4 0.52 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EKX49880.1 - 0.027 14.2 0.1 0.11 12.3 0.1 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 EKX49880.1 - 0.038 13.7 0.1 0.086 12.6 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein CPT PF07931.12 EKX49880.1 - 0.042 13.7 0.0 0.094 12.5 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_24 PF13479.6 EKX49880.1 - 0.065 13.0 0.8 0.13 12.0 0.1 1.9 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EKX49880.1 - 0.082 12.4 0.0 0.2 11.1 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 EKX49880.1 - 0.18 10.9 0.3 1.4 8.0 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 SET PF00856.28 EKX49881.1 - 3.7e-19 69.7 0.8 1.6e-18 67.6 0.8 1.7 1 1 0 1 1 1 1 SET domain Chalcone_3 PF16036.5 EKX49882.1 - 2.6e-16 60.2 0.0 3.9e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Chalcone isomerase-like Chalcone_2 PF16035.5 EKX49882.1 - 6.8e-08 32.5 0.0 0.0014 18.5 0.0 2.2 1 1 1 2 2 2 2 Chalcone isomerase like Chalcone PF02431.15 EKX49882.1 - 0.0033 16.9 0.1 0.23 10.8 0.0 2.2 2 0 0 2 2 2 2 Chalcone-flavanone isomerase Peptidase_C14 PF00656.22 EKX49883.1 - 4.6e-54 184.0 0.0 8.4e-54 183.1 0.0 1.4 1 1 0 1 1 1 1 Caspase domain Collagen PF01391.18 EKX49884.1 - 4.7e-15 55.1 78.4 9.6e-09 34.9 36.3 2.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) AAA_32 PF13654.6 EKX49884.1 - 0.11 11.3 2.5 0.13 11.0 2.5 1.1 1 0 0 1 1 1 0 AAA domain TMPIT PF07851.13 EKX49884.1 - 1.8 7.8 5.7 2.5 7.2 5.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein CitMHS PF03600.16 EKX49885.1 - 0.099 11.8 3.3 0.22 10.7 3.3 1.6 1 1 0 1 1 1 0 Citrate transporter TetR_C_30 PF17939.1 EKX49886.1 - 0.0071 16.6 0.1 0.015 15.5 0.1 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Tetraspanin PF00335.20 EKX49886.1 - 0.02 14.6 0.9 0.027 14.2 0.9 1.2 1 0 0 1 1 1 0 Tetraspanin family Tautomerase PF01361.21 EKX49886.1 - 0.096 12.6 0.4 0.19 11.7 0.4 1.4 1 0 0 1 1 1 0 Tautomerase enzyme MFS_1 PF07690.16 EKX49888.1 - 1.1e-43 149.6 28.9 1.4e-28 99.9 12.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EKX49888.1 - 1.3e-35 123.2 13.7 1.7e-35 122.8 13.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 EKX49888.1 - 0.084 11.7 17.0 0.94 8.3 16.8 2.5 1 1 0 1 1 1 0 MFS_1 like family DUF5624 PF18538.1 EKX49888.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) MgtE PF01769.16 EKX49888.1 - 3.9 7.9 18.6 3.6 8.0 0.3 4.1 2 1 0 2 2 2 0 Divalent cation transporter Tautomerase PF01361.21 EKX49889.1 - 0.018 15.0 0.1 0.038 13.9 0.1 1.5 1 0 0 1 1 1 0 Tautomerase enzyme DUF3262 PF11660.8 EKX49889.1 - 0.024 15.0 3.5 0.064 13.7 3.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) TetR_C_30 PF17939.1 EKX49889.1 - 0.024 14.9 0.1 0.052 13.8 0.1 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain FAD_binding_3 PF01494.19 EKX49890.1 - 1.5e-57 195.4 0.0 5.2e-28 98.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EKX49890.1 - 1.7e-06 27.5 0.0 0.00091 18.5 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EKX49890.1 - 0.00025 21.5 0.0 0.081 13.5 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EKX49890.1 - 0.0012 18.1 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EKX49890.1 - 0.0014 17.7 0.3 1.1 8.2 0.0 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.24 EKX49890.1 - 0.0089 15.6 0.8 0.026 14.1 0.8 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EKX49890.1 - 0.0098 16.1 0.1 0.029 14.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EKX49890.1 - 0.058 12.5 0.2 0.11 11.6 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 EKX49890.1 - 0.072 11.8 0.1 0.15 10.7 0.1 1.5 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 EKX49890.1 - 0.088 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 EKX49890.1 - 0.13 12.5 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain DEAD PF00270.29 EKX49893.1 - 2.3e-42 144.7 0.1 6.4e-42 143.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX49893.1 - 1e-26 93.5 0.1 4e-26 91.5 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX49893.1 - 3.7e-07 30.3 0.0 6.5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EKX49893.1 - 0.019 15.2 0.7 0.36 11.1 0.7 2.7 1 1 0 1 1 1 0 AAA domain RWP-RK PF02042.15 EKX49894.1 - 2e-14 53.3 0.0 4.3e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX49895.1 - 1.6e-14 53.6 0.0 3.4e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain SIT PF15330.6 EKX49896.1 - 0.11 12.9 0.1 0.11 12.9 0.1 3.3 3 1 1 4 4 4 0 SHP2-interacting transmembrane adaptor protein, SIT RabGAP-TBC PF00566.18 EKX49897.1 - 2.9e-28 99.0 1.7 3.3e-27 95.6 0.2 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SH3_1 PF00018.28 EKX49897.1 - 8.1e-07 28.6 0.0 1.8e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain Mcp5_PH PF12814.7 EKX49897.1 - 8.1e-05 22.7 0.1 0.00046 20.3 0.1 2.0 1 1 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology SH3_9 PF14604.6 EKX49897.1 - 0.00011 22.0 0.1 0.00023 20.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EKX49897.1 - 0.0017 18.0 0.0 0.0058 16.3 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain PH PF00169.29 EKX49897.1 - 0.0047 17.4 0.0 0.013 16.0 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF3958 PF13125.6 EKX49897.1 - 1.1 9.5 6.7 1.5 9.1 4.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) HypD PF01924.16 EKX49898.1 - 0.042 12.9 0.9 0.057 12.5 0.9 1.1 1 0 0 1 1 1 0 Hydrogenase formation hypA family MSL2-CXC PF16682.5 EKX49898.1 - 2 8.6 8.3 0.12 12.5 2.8 1.8 2 0 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 COR PF16095.5 EKX49899.1 - 0.024 14.5 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 C-terminal of Roc, COR, domain Lig_C PF18330.1 EKX49899.1 - 0.18 11.8 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region Nrap_D3 PF17404.2 EKX49904.1 - 5.8e-34 117.5 0.1 1.8e-33 115.9 0.0 2.0 2 0 0 2 2 2 1 Nrap protein domain 3 Nrap PF03813.14 EKX49904.1 - 6.9e-33 113.9 0.0 1.2e-32 113.1 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D2 PF17403.2 EKX49904.1 - 1.3e-28 99.7 0.1 2.6e-28 98.7 0.1 1.6 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain Nrap_D4 PF17405.2 EKX49904.1 - 1.9e-25 89.5 0.1 3.1e-25 88.8 0.1 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D6 PF17407.2 EKX49904.1 - 6e-15 55.7 0.0 1.4e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 Nrap protein domain 6 Nrap_D5 PF17406.2 EKX49904.1 - 8.6e-05 22.4 0.1 0.18 11.5 0.0 2.5 1 1 1 2 2 2 2 Nrap protein PAP/OAS1-like domain 5 Alpha_kinase PF02816.18 EKX49905.1 - 3.6e-58 196.7 0.0 4.3e-58 196.5 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Methyltransf_22 PF13383.6 EKX49907.1 - 2.9e-06 27.0 0.7 0.0065 16.1 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain NUDIX PF00293.28 EKX49908.1 - 1.9e-07 31.2 0.1 3.4e-07 30.4 0.1 1.5 1 1 0 1 1 1 1 NUDIX domain Chlamy_scaf PF09675.10 EKX49908.1 - 0.03 14.7 0.0 0.057 13.8 0.0 1.5 1 0 0 1 1 1 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) NAGidase PF07555.13 EKX49908.1 - 0.055 12.8 0.0 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase DUF1134 PF06577.12 EKX49909.1 - 0.09 12.5 0.1 0.19 11.5 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1134) Pkinase PF00069.25 EKX49910.1 - 1.7e-29 103.0 0.0 2.6e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX49910.1 - 6.2e-29 101.1 0.0 9.3e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX49910.1 - 0.089 11.6 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EKX49910.1 - 0.1 12.5 0.1 0.28 11.1 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Vac14_Fig4_bd PF11916.8 EKX49911.1 - 4.6e-50 169.8 0.2 4.6e-50 169.8 0.2 2.6 3 1 0 3 3 3 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 EKX49911.1 - 5.4e-41 139.1 0.0 1.8e-37 127.8 0.0 3.3 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EKX49911.1 - 2.2e-11 43.0 2.7 8e-05 22.6 0.0 6.0 5 0 0 5 5 4 1 HEAT repeat Cnd1 PF12717.7 EKX49911.1 - 6.7e-08 32.7 1.8 0.62 10.1 0.0 4.4 3 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Tti2 PF10521.9 EKX49911.1 - 8.4e-06 25.5 0.8 0.17 11.4 0.1 3.7 2 1 2 4 4 4 2 Tti2 family RTP1_C1 PF10363.9 EKX49911.1 - 2.6e-05 24.4 2.3 0.25 11.5 0.0 5.0 2 1 2 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EKX49911.1 - 0.00055 20.4 5.6 0.034 14.7 0.1 5.2 5 1 0 5 5 5 1 HEAT-like repeat Dopey_N PF04118.14 EKX49911.1 - 0.00066 18.9 0.6 0.41 9.7 0.2 2.4 2 0 0 2 2 2 2 Dopey, N-terminal HEAT_2 PF13646.6 EKX49911.1 - 0.00084 19.7 0.8 11 6.5 0.0 4.8 5 1 0 5 5 4 1 HEAT repeats RICTOR_N PF14664.6 EKX49911.1 - 0.021 13.8 0.2 6.8 5.6 0.0 2.6 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term TIP120 PF08623.10 EKX49911.1 - 0.033 14.0 0.3 4.3 7.1 0.0 3.2 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) Arm PF00514.23 EKX49911.1 - 0.078 13.1 5.7 4.1 7.6 0.0 5.5 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Ppx-GppA PF02541.16 EKX49911.1 - 0.17 11.3 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family RasGEF_N_2 PF14663.6 EKX49911.1 - 0.94 9.9 6.7 7.9 6.9 0.0 4.4 3 2 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF4813 PF16072.5 EKX49913.1 - 0.021 14.5 59.9 0.028 14.1 59.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) HTH_Tnp_Tc5 PF03221.16 EKX49915.1 - 2.4e-13 49.9 1.2 3.7e-13 49.3 0.6 1.7 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_38 PF13936.6 EKX49915.1 - 0.0002 21.1 1.2 0.00036 20.2 1.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 EKX49915.1 - 0.0004 20.1 0.1 0.0004 20.1 0.1 2.5 3 1 0 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.6 EKX49915.1 - 0.0013 18.8 0.0 0.0047 17.0 0.0 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_1 PF01527.20 EKX49915.1 - 0.0029 17.9 1.2 0.52 10.7 0.3 2.3 2 0 0 2 2 2 2 Transposase TnsD PF15978.5 EKX49915.1 - 0.0052 15.8 0.6 0.0056 15.7 0.6 1.1 1 0 0 1 1 1 1 Tn7-like transposition protein D HTH_6 PF01418.17 EKX49915.1 - 0.0054 16.7 0.3 3.7 7.6 0.1 2.4 1 1 0 2 2 2 2 Helix-turn-helix domain, rpiR family CENP-B_N PF04218.13 EKX49915.1 - 0.0076 15.9 0.7 0.014 15.1 0.7 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain BrkDBD PF09607.10 EKX49915.1 - 0.0092 15.7 0.1 0.026 14.3 0.1 1.8 1 0 0 1 1 1 1 Brinker DNA-binding domain HTH_50 PF18024.1 EKX49915.1 - 0.011 15.3 0.1 0.019 14.6 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain GoLoco PF02188.17 EKX49915.1 - 0.056 13.0 0.9 1.3 8.6 0.0 2.8 3 0 0 3 3 3 0 GoLoco motif Dimerisation2 PF16864.5 EKX49915.1 - 0.057 13.4 0.1 0.63 10.1 0.0 2.1 2 0 0 2 2 2 0 Dimerisation domain DUF4455 PF14643.6 EKX49916.1 - 1.3e-58 198.8 35.8 1.3e-58 198.8 35.8 3.8 4 1 0 4 4 4 2 Domain of unknown function (DUF4455) DUF4456 PF14644.6 EKX49916.1 - 2.3e-30 105.9 3.6 2.3e-30 105.9 3.6 3.9 5 0 0 5 5 5 1 Domain of unknown function (DUF4456) tRNA-synt_1c PF00749.21 EKX49918.1 - 8.4e-103 343.5 0.0 1.1e-102 343.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EKX49918.1 - 1.2e-59 201.1 0.0 1.9e-59 200.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_bind PF01588.20 EKX49918.1 - 1.7e-31 108.2 0.1 3.2e-31 107.3 0.1 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain ApbA_C PF08546.11 EKX49919.1 - 7.3e-26 90.8 1.2 8.9e-23 80.9 1.2 2.8 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EKX49919.1 - 1.2e-14 54.2 0.4 2e-14 53.5 0.4 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 EKX49919.1 - 0.16 12.6 1.7 3.9 8.1 1.7 2.4 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Plus-3 PF03126.18 EKX49920.1 - 8.9e-25 87.3 0.1 3.1e-24 85.6 0.1 2.0 1 0 0 1 1 1 1 Plus-3 domain NodZ PF05830.11 EKX49920.1 - 0.07 11.9 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) Goodbye PF17109.5 EKX49920.1 - 0.17 12.3 7.2 0.18 12.3 2.3 2.9 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain Vps26 PF03643.15 EKX49921.1 - 8.5e-113 375.9 2.8 9.7e-113 375.7 2.8 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EKX49921.1 - 0.011 15.8 0.5 9.1 6.3 0.1 3.0 2 1 1 3 3 3 0 Arrestin (or S-antigen), N-terminal domain LigT_PEase PF02834.16 EKX49922.1 - 1.6e-06 28.2 0.1 3.7e-06 27.0 0.1 1.6 1 1 0 1 1 1 1 LigT like Phosphoesterase PMEI PF04043.15 EKX49922.1 - 0.084 13.2 0.1 0.12 12.8 0.1 1.2 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor TIG PF01833.24 EKX49923.1 - 4.6e-17 61.9 12.0 2.2e-08 34.1 0.1 7.7 6 0 0 6 6 6 3 IPT/TIG domain Big_9 PF17963.1 EKX49923.1 - 1.2e-09 38.8 34.0 0.86 10.4 0.0 15.3 16 1 0 16 16 16 3 Bacterial Ig domain EPTP PF03736.17 EKX49923.1 - 3.8e-05 23.6 11.3 0.081 12.9 0.1 6.8 7 0 0 7 7 7 2 EPTP domain Laminin_G_3 PF13385.6 EKX49923.1 - 0.00036 20.7 0.1 0.0067 16.6 0.0 3.2 2 1 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Lactonase PF10282.9 EKX49923.1 - 0.0013 18.0 0.1 0.017 14.4 0.0 2.6 2 1 1 3 3 3 2 Lactonase, 7-bladed beta-propeller NOB1_Zn_bind PF08772.11 EKX49924.1 - 8.3e-26 89.9 3.4 1.5e-25 89.2 3.4 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 EKX49924.1 - 8.4e-16 58.3 0.0 1.2e-10 41.7 0.1 2.5 1 1 1 2 2 2 2 PIN domain of ribonuclease CAF20 PF17052.5 EKX49924.1 - 0.012 15.7 0.1 7.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Cap associated factor 2OG-FeII_Oxy_3 PF13640.6 EKX49925.1 - 5e-14 53.0 0.0 6.2e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 EKX49925.1 - 7.9e-11 42.5 0.0 9.8e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rubi_NSP_C PF12601.8 EKX49927.1 - 0.079 13.1 0.1 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 Rubivirus non-structural protein Zn_clus PF00172.18 EKX49928.1 - 1e-20 73.5 50.2 5.8e-08 32.7 9.2 3.5 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 EKX49929.1 - 9.7e-21 73.6 50.2 5.6e-08 32.8 9.2 3.5 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain Tropomyosin_1 PF12718.7 EKX49930.1 - 0.0097 16.1 3.3 0.0097 16.1 3.3 5.4 3 1 2 5 5 5 1 Tropomyosin like DUF4618 PF15397.6 EKX49930.1 - 0.69 9.3 36.3 0.29 10.5 0.6 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4618) HOOK PF05622.12 EKX49930.1 - 2.3 6.2 51.3 0.019 13.1 4.9 4.6 3 1 2 5 5 5 0 HOOK protein IMPa_helical PF18642.1 EKX49930.1 - 2.4 8.6 6.6 7.9 6.9 0.5 2.9 2 0 0 2 2 2 0 Immunomodulating metalloprotease helical domain Mif2_N PF15624.6 EKX49930.1 - 5.6 7.7 8.1 28 5.4 5.4 3.0 2 0 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Ribosomal_S17_N PF16205.5 EKX49931.1 - 2.2e-27 95.2 0.2 2.2e-27 95.2 0.2 1.6 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EKX49931.1 - 2.4e-26 91.6 2.0 3.5e-26 91.1 2.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 PRF PF06875.11 EKX49931.1 - 0.06 12.8 0.2 0.09 12.2 0.2 1.2 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF DASH_Dad4 PF08650.10 EKX49932.1 - 0.0065 16.4 0.4 0.071 13.1 0.0 2.1 1 1 1 2 2 2 1 DASH complex subunit Dad4 PI3K_P85_iSH2 PF16454.5 EKX49932.1 - 0.046 13.3 3.9 0.09 12.4 1.0 2.0 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain NAAA-beta PF15508.6 EKX49932.1 - 0.051 13.9 0.1 0.08 13.3 0.1 1.3 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase UvrD_C PF13361.6 EKX49932.1 - 0.058 12.8 0.1 0.06 12.7 0.1 1.1 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Eclosion PF04736.12 EKX49932.1 - 0.11 12.2 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Eclosion hormone FlaC_arch PF05377.11 EKX49932.1 - 0.12 12.7 1.3 2.6 8.5 0.0 2.3 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Mito_carr PF00153.27 EKX49933.1 - 1.4e-52 175.5 1.0 1.3e-17 63.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_I_A49 PF06870.12 EKX49934.1 - 3e-54 184.4 0.4 3.6e-54 184.1 0.4 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Methyltransf_4 PF02390.17 EKX49935.1 - 1.3e-31 109.4 0.0 1.8e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 EKX49935.1 - 5e-08 32.9 0.0 7.9e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX49935.1 - 1.3e-05 25.8 0.0 2.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX49935.1 - 6.2e-05 23.7 0.0 0.0001 23.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EKX49935.1 - 0.0008 19.4 0.0 0.00099 19.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX49935.1 - 0.0055 17.3 0.0 0.0094 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EKX49935.1 - 0.033 13.7 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain DOT1 PF08123.13 EKX49935.1 - 0.07 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 MetW PF07021.12 EKX49935.1 - 0.19 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW S4 PF01479.25 EKX49936.1 - 6.5e-11 41.8 0.8 6.5e-11 41.8 0.8 1.9 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 EKX49936.1 - 6.3e-05 23.8 1.3 9.7e-05 23.2 0.4 1.8 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Thioredoxin PF00085.20 EKX49937.1 - 3.9e-19 68.6 0.0 6.3e-18 64.7 0.0 2.2 1 1 0 1 1 1 1 Thioredoxin EGF_MSP1_1 PF12946.7 EKX49937.1 - 2.7e-05 24.1 6.3 0.058 13.4 0.4 2.5 2 0 0 2 2 2 2 MSP1 EGF domain 1 cEGF PF12662.7 EKX49937.1 - 0.00012 21.9 6.0 0.099 12.6 0.3 2.5 2 0 0 2 2 2 2 Complement Clr-like EGF-like Thioredoxin_2 PF13098.6 EKX49937.1 - 0.00037 20.9 0.0 0.00093 19.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain EB PF01683.18 EKX49937.1 - 0.015 15.6 10.2 0.47 10.8 0.9 2.6 2 1 0 2 2 2 0 EB module OST3_OST6 PF04756.13 EKX49937.1 - 0.015 14.6 0.0 0.02 14.3 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family TIL PF01826.17 EKX49937.1 - 0.018 15.3 5.9 1.2 9.5 0.5 2.5 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain AhpC-TSA PF00578.21 EKX49937.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family hEGF PF12661.7 EKX49937.1 - 0.15 12.7 11.4 0.64 10.7 0.5 3.9 4 0 0 4 4 4 0 Human growth factor-like EGF Gly_transf_sug PF04488.15 EKX49938.1 - 1.7e-15 57.5 0.0 2e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 EKX49938.1 - 7.4e-07 28.8 1.0 0.0032 16.8 0.0 2.0 1 1 1 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.12 EKX49938.1 - 0.0089 15.4 0.0 0.0089 15.4 0.0 1.1 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein BTB PF00651.31 EKX49940.1 - 3.6e-11 43.3 0.9 6.8e-11 42.4 0.1 1.8 2 0 0 2 2 2 1 BTB/POZ domain SelR PF01641.18 EKX49942.1 - 9.9e-27 93.4 0.5 1.1e-26 93.3 0.5 1.0 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 EKX49942.1 - 0.0062 16.7 0.1 0.012 15.9 0.1 1.5 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF678 PF05077.12 EKX49942.1 - 0.018 15.2 0.2 8.1 6.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF678) Zn_ribbon_recom PF13408.6 EKX49942.1 - 0.026 15.0 4.1 0.5 10.9 0.4 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain 2OG-FeII_Oxy PF03171.20 EKX49943.1 - 1.2e-06 28.9 0.0 2.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EKX49943.1 - 6.4e-06 26.9 0.0 1.2e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Utp12 PF04003.12 EKX49944.1 - 6.4e-21 74.7 2.2 9.5e-21 74.1 2.2 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.32 EKX49944.1 - 1.7e-08 34.9 9.0 1e-06 29.3 0.0 5.1 6 1 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX49944.1 - 9.8e-06 25.8 0.2 0.55 10.6 0.0 4.2 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 EKX49944.1 - 0.051 13.3 0.2 2.3 7.9 0.2 3.2 3 1 1 4 4 4 0 TUP1-like enhancer of split FUN14 PF04930.15 EKX49945.1 - 2e-06 28.1 0.4 3.8e-06 27.2 0.4 1.6 1 1 0 1 1 1 1 FUN14 family Ribophorin_II PF05817.14 EKX49946.1 - 0.011 14.4 1.9 0.67 8.4 0.0 2.1 1 1 0 2 2 2 0 Oligosaccharyltransferase subunit Ribophorin II Rep_fac_C PF08542.11 EKX49946.1 - 0.015 15.6 1.6 0.14 12.6 0.1 2.7 3 0 0 3 3 3 0 Replication factor C C-terminal domain UBN_AB PF14075.6 EKX49946.1 - 0.032 14.0 2.5 1.4 8.6 0.3 2.5 2 0 0 2 2 2 0 Ubinuclein conserved middle domain DUF1178 PF06676.11 EKX49946.1 - 0.032 14.6 0.9 0.099 13.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) Cse1 PF08506.10 EKX49946.1 - 0.09 11.6 1.3 0.11 11.3 0.3 1.6 2 0 0 2 2 2 0 Cse1 Lant_dehydr_C PF14028.6 EKX49946.1 - 0.16 11.5 0.2 0.27 10.7 0.2 1.4 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term Vip3A_N PF12495.8 EKX49946.1 - 0.53 10.2 2.8 0.38 10.6 0.2 2.0 3 0 0 3 3 3 0 Vegetative insecticide protein 3A N terminal DUF5349 PF17298.2 EKX49948.1 - 0.044 13.5 1.8 0.05 13.4 1.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) adh_short PF00106.25 EKX49949.1 - 9e-24 84.0 0.0 2.2e-21 76.2 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EKX49949.1 - 8.3e-13 48.4 0.0 1.8e-11 44.0 0.0 2.2 1 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX49949.1 - 2.2e-06 27.7 0.0 4.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EKX49949.1 - 0.0099 15.4 0.0 0.032 13.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.8 EKX49949.1 - 0.058 13.2 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase BACK PF07707.15 EKX49950.1 - 3.7e-08 33.4 0.1 5e-07 29.8 0.0 2.7 2 0 0 2 2 2 1 BTB And C-terminal Kelch IQ PF00612.27 EKX49950.1 - 0.0092 15.7 0.2 0.045 13.6 0.2 2.3 1 0 0 1 1 1 1 IQ calmodulin-binding motif Kelch_5 PF13854.6 EKX49950.1 - 0.036 14.1 2.6 1.2 9.2 0.0 3.2 4 0 0 4 4 4 0 Kelch motif Kelch_6 PF13964.6 EKX49950.1 - 0.042 14.2 0.0 20 5.6 0.0 3.3 3 0 0 3 3 3 0 Kelch motif COG5 PF10392.9 EKX49950.1 - 0.054 13.7 4.8 0.24 11.6 4.8 2.1 1 0 0 1 1 1 0 Golgi transport complex subunit 5 RWP-RK PF02042.15 EKX49951.1 - 1.1e-15 57.3 0.1 2e-15 56.5 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain MIR PF02815.19 EKX49952.1 - 1.4e-10 41.3 0.1 6e-07 29.5 0.0 2.4 1 1 1 2 2 2 2 MIR domain Ins145_P3_rec PF08709.11 EKX49952.1 - 0.0022 17.2 0.0 0.0028 16.9 0.0 1.2 1 0 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor DUF2956 PF11169.8 EKX49953.1 - 3.4 7.9 6.0 5.9 7.1 6.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2956) Col_cuticle_N PF01484.17 EKX49954.1 - 0.65 10.1 5.9 0.92 9.6 4.2 2.0 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain AAA_6 PF12774.7 EKX49956.1 - 4.8e-155 515.5 0.2 1.5e-154 513.9 0.0 2.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EKX49956.1 - 3e-129 431.6 6.5 3e-129 431.6 6.5 2.1 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EKX49956.1 - 6.7e-106 353.4 0.0 7.9e-105 349.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EKX49956.1 - 1.4e-104 349.6 0.0 2e-103 345.8 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EKX49956.1 - 3.2e-88 294.5 0.8 1.5e-87 292.3 0.8 2.3 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 EKX49956.1 - 8.7e-78 260.0 0.0 8.7e-75 250.2 0.0 3.7 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EKX49956.1 - 3e-54 183.2 0.6 9.9e-54 181.6 0.1 2.3 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 EKX49956.1 - 2.4e-46 158.3 9.3 2.4e-46 158.3 9.3 2.4 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EKX49956.1 - 6.1e-42 142.5 0.0 3.8e-40 136.7 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EKX49956.1 - 2.1e-30 105.4 0.2 1.4e-29 102.7 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EKX49956.1 - 4.3e-16 59.2 0.0 7.9e-05 22.7 0.0 5.5 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 EKX49956.1 - 1.4e-14 54.1 0.1 6.8e-14 51.9 0.1 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 EKX49956.1 - 4.9e-07 30.2 0.3 0.57 10.6 0.0 5.1 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EKX49956.1 - 0.00049 20.4 0.1 3.9 7.7 0.0 5.2 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.6 EKX49956.1 - 0.0035 17.5 0.0 12 6.1 0.0 3.9 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 EKX49956.1 - 0.0039 17.7 0.0 0.1 13.1 0.0 3.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EKX49956.1 - 0.015 15.7 0.1 15 6.0 0.0 3.8 3 0 0 3 3 3 0 RNA helicase T2SSE PF00437.20 EKX49956.1 - 0.061 12.4 0.3 0.18 10.9 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.6 EKX49956.1 - 0.083 12.6 0.0 5.7 6.6 0.1 2.6 2 0 0 2 2 2 0 AAA domain GAGBD PF16828.5 EKX49956.1 - 0.69 10.0 3.3 0.52 10.4 0.3 2.4 2 0 0 2 2 2 0 GAG-binding domain on surface antigen PI3K_P85_iSH2 PF16454.5 EKX49956.1 - 7.9 6.0 12.8 2.1 7.9 0.5 4.0 3 0 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain WD40_3 PF15911.5 EKX49957.1 - 0.0046 16.9 0.1 0.01 15.8 0.1 1.6 1 0 0 1 1 1 1 WD domain, G-beta repeat DPPIV_N PF00930.21 EKX49957.1 - 0.13 10.9 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region RAB3GAP2_N PF14655.6 EKX49958.1 - 0.038 13.3 0.8 8.6 5.5 0.0 2.6 1 1 2 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40 PF00400.32 EKX49958.1 - 0.056 14.3 2.3 6.9 7.7 0.0 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat Fer4_6 PF12837.7 EKX49958.1 - 0.14 12.3 1.7 0.46 10.6 0.6 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain TNFR_c6 PF00020.18 EKX49958.1 - 0.19 12.2 2.9 6.2 7.3 0.8 2.6 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region Sel1 PF08238.12 EKX49959.1 - 2.1e-13 50.4 8.1 0.00052 20.6 0.0 6.4 6 0 0 6 6 6 5 Sel1 repeat DUF2650 PF10853.8 EKX49959.1 - 0.23 11.2 2.2 2 8.2 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2650) DUF4854 PF16146.5 EKX49960.1 - 0.021 15.2 0.2 0.023 15.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4854) MYEOV2 PF15004.6 EKX49960.1 - 0.025 15.0 0.1 0.035 14.5 0.1 1.2 1 0 0 1 1 1 0 Myeloma-overexpressed-like PAP_fibrillin PF04755.12 EKX49961.1 - 1.9e-09 37.8 0.0 7.7e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 PAP_fibrillin Cupin_8 PF13621.6 EKX49962.1 - 5.1e-28 98.5 1.2 7.1e-27 94.7 1.2 2.0 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EKX49962.1 - 5.5e-13 49.3 0.1 1.3e-12 48.2 0.1 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EKX49962.1 - 0.062 13.0 0.0 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Cupin domain F-box-like PF12937.7 EKX49962.1 - 0.069 13.1 0.2 0.16 11.9 0.2 1.6 1 0 0 1 1 1 0 F-box-like Cupin_1 PF00190.22 EKX49962.1 - 0.085 12.5 0.0 0.18 11.4 0.0 1.5 2 0 0 2 2 2 0 Cupin Pkinase PF00069.25 EKX49963.1 - 4.7e-25 88.4 0.0 5.3e-25 88.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX49963.1 - 1.7e-16 60.3 0.0 2e-16 60.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX49963.1 - 0.039 13.3 0.1 0.071 12.4 0.1 1.6 1 1 0 1 1 1 0 Kinase-like GvpG PF05120.12 EKX49964.1 - 0.69 10.0 4.4 0.58 10.2 0.2 3.1 3 1 0 3 3 3 0 Gas vesicle protein G AAA_6 PF12774.7 EKX49966.1 - 4.7e-156 518.8 0.0 3.4e-155 516.0 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EKX49966.1 - 2.4e-133 445.1 7.7 2.4e-133 445.1 7.7 3.9 4 1 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 EKX49966.1 - 1.6e-104 349.4 0.7 5.5e-104 347.7 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 EKX49966.1 - 1.6e-103 345.5 0.0 5.6e-103 343.8 0.0 2.1 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EKX49966.1 - 3.2e-85 284.7 1.0 2.3e-84 282.0 1.0 2.7 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 EKX49966.1 - 4.5e-76 254.4 0.1 1.5e-72 243.0 0.0 4.0 4 0 0 4 4 4 1 P-loop containing dynein motor region MT PF12777.7 EKX49966.1 - 1e-56 192.4 14.7 1.3e-56 192.1 13.0 2.0 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 EKX49966.1 - 9e-55 184.9 0.0 2.6e-54 183.4 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EKX49966.1 - 8.3e-45 151.7 0.0 2.5e-43 147.0 0.0 3.4 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EKX49966.1 - 9.7e-29 100.1 2.8 5.9e-28 97.5 1.1 3.1 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EKX49966.1 - 1.6e-21 76.3 0.1 1.5e-20 73.2 0.1 2.7 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 EKX49966.1 - 1.2e-16 60.9 0.0 1.2e-05 25.3 0.0 6.1 4 2 1 5 5 5 3 AAA domain (dynein-related subfamily) AAA PF00004.29 EKX49966.1 - 0.00029 21.3 0.9 1.3 9.5 0.0 4.7 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EKX49966.1 - 0.00033 21.0 0.1 0.95 9.9 0.0 4.1 4 0 0 4 4 3 1 RNA helicase AAA_22 PF13401.6 EKX49966.1 - 0.00081 19.7 0.9 1.2 9.4 0.0 4.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EKX49966.1 - 0.0026 18.2 5.4 5.2 7.4 0.0 5.4 6 0 0 6 6 4 1 AAA ATPase domain AAA_18 PF13238.6 EKX49966.1 - 0.0073 16.9 0.6 2.9 8.4 0.0 4.2 4 0 0 4 4 3 1 AAA domain MCM PF00493.23 EKX49966.1 - 0.012 14.7 0.1 1.3 8.0 0.0 2.5 2 0 0 2 2 2 0 MCM P-loop domain DEAD PF00270.29 EKX49966.1 - 0.058 13.2 0.0 16 5.2 0.0 3.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase Sigma54_activat PF00158.26 EKX49966.1 - 0.062 13.0 0.7 0.84 9.3 0.0 2.7 3 0 0 3 3 2 0 Sigma-54 interaction domain RYDR_ITPR PF01365.21 EKX49966.1 - 0.13 11.7 5.0 1.8 7.9 0.3 3.8 4 0 0 4 4 4 0 RIH domain AAA_30 PF13604.6 EKX49966.1 - 0.19 11.4 2.4 2.1 8.0 0.1 3.0 3 0 0 3 3 3 0 AAA domain Sel1 PF08238.12 EKX49967.1 - 3.2e-10 40.3 0.1 0.00028 21.5 0.0 2.8 3 0 0 3 3 3 2 Sel1 repeat MIB_HERC2 PF06701.13 EKX49969.1 - 1.7e-14 53.8 2.6 1.7e-14 53.8 2.6 2.3 2 0 0 2 2 2 1 Mib_herc2 DUF810 PF05664.11 EKX49969.1 - 7.2e-05 21.5 0.0 0.00029 19.5 0.0 2.0 2 0 0 2 2 2 1 Plant family of unknown function (DUF810) CENP-X PF09415.10 EKX49969.1 - 0.064 13.6 0.0 5.1 7.5 0.0 2.9 2 0 0 2 2 2 0 CENP-S associating Centromere protein X Membr_traf_MHD PF10540.9 EKX49969.1 - 0.13 12.4 0.7 24 5.1 0.0 3.0 2 1 0 3 3 3 0 Munc13 (mammalian uncoordinated) homology domain DHHC PF01529.20 EKX49970.1 - 2e-13 50.6 7.8 2.9e-13 50.1 7.8 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase LapA_dom PF06305.11 EKX49970.1 - 0.27 11.1 0.8 0.48 10.3 0.8 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain RCC1 PF00415.18 EKX49971.1 - 7.4e-87 285.8 11.7 1.8e-12 47.6 0.3 8.4 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX49971.1 - 1.5e-49 164.9 30.5 4.4e-08 32.7 0.2 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat GAD-like PF08887.11 EKX49971.1 - 0.041 13.7 0.0 11 5.8 0.0 2.8 2 0 0 2 2 2 0 GAD-like domain ACBP PF00887.19 EKX49972.1 - 1.9e-27 95.3 3.0 2e-27 95.2 3.0 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.18 EKX49972.1 - 0.018 15.4 0.1 0.021 15.2 0.1 1.3 1 1 0 1 1 1 0 FERM central domain RsgA_GTPase PF03193.16 EKX49973.1 - 0.0011 18.9 0.0 0.0038 17.1 0.0 1.9 1 0 0 1 1 1 1 RsgA GTPase PLN_propep PF16485.5 EKX49973.1 - 0.0054 16.4 0.2 0.016 14.9 0.2 1.9 1 0 0 1 1 1 1 Protealysin propeptide ABC_tran PF00005.27 EKX49973.1 - 0.018 15.6 0.1 0.13 12.8 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_21 PF13304.6 EKX49973.1 - 0.035 13.9 3.2 0.19 11.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 EKX49973.1 - 0.037 13.5 0.0 0.18 11.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 EKX49973.1 - 0.11 12.5 0.1 2.5 8.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 EKX49973.1 - 0.18 11.6 0.0 0.4 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EKX49973.1 - 0.27 11.7 0.0 0.27 11.7 0.0 4.9 3 1 0 4 4 4 0 AAA domain PDZ_6 PF17820.1 EKX49975.1 - 8.1e-07 28.8 0.1 2e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 PDZ domain CH PF00307.31 EKX49975.1 - 1.9e-05 24.8 0.0 4e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain PDZ PF00595.24 EKX49975.1 - 7.8e-05 23.0 0.0 0.00022 21.5 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX49975.1 - 0.0058 16.9 0.0 0.026 14.9 0.0 2.1 2 0 0 2 2 2 1 PDZ domain RPN2_C PF18004.1 EKX49975.1 - 0.016 15.2 0.3 0.069 13.1 0.3 2.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PBP1_TM PF14812.6 EKX49975.1 - 7.6 7.0 13.3 5.5 7.4 5.4 3.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sugar_tr PF00083.24 EKX49976.1 - 1e-19 70.7 6.6 1e-19 70.7 6.6 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EKX49976.1 - 1.3e-16 60.4 33.6 2e-07 30.3 11.1 3.8 2 2 1 3 3 3 3 Major Facilitator Superfamily DUF3677 PF12432.8 EKX49977.1 - 4.3e-11 43.0 2.5 8e-11 42.1 0.5 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3677) Endotoxin_N PF03945.14 EKX49977.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain TPR_10 PF13374.6 EKX49979.1 - 1e-06 28.4 3.6 0.1 12.5 0.2 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX49979.1 - 1.4e-05 24.7 2.7 0.0043 16.8 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat FHA PF00498.26 EKX49979.1 - 1.7e-05 25.1 0.0 3.9e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 FHA domain TPR_7 PF13176.6 EKX49979.1 - 0.00011 22.0 4.2 0.073 13.1 0.3 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX49979.1 - 0.00086 19.9 1.5 0.0079 16.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat SNAP PF14938.6 EKX49979.1 - 0.0023 17.4 1.0 0.012 15.1 0.1 2.5 3 0 0 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 EKX49979.1 - 0.0035 17.3 9.4 0.4 10.9 1.1 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX49979.1 - 0.0052 17.0 11.0 0.015 15.6 2.9 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat Methyltransf_23 PF13489.6 EKX49979.1 - 0.021 14.7 0.0 0.083 12.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain MIT PF04212.18 EKX49979.1 - 0.063 13.4 4.6 8.9 6.5 0.0 4.0 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_MalT PF17874.1 EKX49979.1 - 0.073 12.4 0.8 0.14 11.5 0.8 1.4 1 0 0 1 1 1 0 MalT-like TPR region Ion_trans_2 PF07885.16 EKX49980.1 - 3.5e-08 33.3 6.1 8.6e-08 32.0 6.1 1.6 1 0 0 1 1 1 1 Ion channel T3SS_ExsE PF18286.1 EKX49980.1 - 0.13 12.2 1.5 4.5 7.3 0.3 3.2 3 0 0 3 3 3 0 Type III secretion system ExsE FAM76 PF16046.5 EKX49980.1 - 0.16 11.3 2.1 0.34 10.2 2.1 1.5 1 0 0 1 1 1 0 FAM76 protein SK_channel PF03530.14 EKX49980.1 - 0.19 11.7 0.1 0.19 11.7 0.1 2.2 3 0 0 3 3 3 0 Calcium-activated SK potassium channel Pkinase_Tyr PF07714.17 EKX49981.1 - 1.2e-46 159.1 0.0 2e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX49981.1 - 1.8e-46 158.7 0.0 2.7e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EKX49981.1 - 0.00064 19.7 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fes1 PF08609.10 EKX49983.1 - 9.7e-05 23.2 1.3 9.7e-05 23.2 1.3 2.1 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 BLOC1_2 PF10046.9 EKX49983.1 - 0.016 15.5 0.3 0.032 14.5 0.3 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SIL1 PF16782.5 EKX49983.1 - 0.02 14.1 0.0 0.04 13.1 0.0 1.5 1 1 0 1 1 1 0 Nucleotide exchange factor SIL1 Fzo_mitofusin PF04799.13 EKX49983.1 - 0.069 12.7 1.1 1.4 8.4 0.1 2.2 2 0 0 2 2 2 0 fzo-like conserved region Dpy-30 PF05186.13 EKX49984.1 - 7.6e-18 63.9 0.2 1.5e-17 63.0 0.2 1.5 1 0 0 1 1 1 1 Dpy-30 motif ADK PF00406.22 EKX49984.1 - 0.00072 19.7 0.0 0.059 13.5 0.0 2.5 2 0 0 2 2 2 1 Adenylate kinase RR_TM4-6 PF06459.12 EKX49984.1 - 2.8 7.7 6.9 5.5 6.7 6.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RWP-RK PF02042.15 EKX49985.1 - 1.4e-16 60.2 0.5 3.2e-16 59.0 0.1 1.9 2 0 0 2 2 2 1 RWP-RK domain HTH_50 PF18024.1 EKX49985.1 - 0.11 12.1 0.1 0.23 11.1 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_6 PF01418.17 EKX49985.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family YqaJ PF09588.10 EKX49986.1 - 4.4e-22 78.8 0.0 5.8e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain Cauli_AT PF03233.13 EKX49987.1 - 0.99 9.3 13.1 0.81 9.6 0.3 3.4 2 2 1 3 3 3 0 Aphid transmission protein VWA_2 PF13519.6 EKX49987.1 - 1.3 9.7 6.3 8 7.2 0.1 3.8 1 1 3 4 4 4 0 von Willebrand factor type A domain Phage_GP20 PF06810.11 EKX49987.1 - 4.1 7.2 21.2 1 9.2 0.2 3.4 4 0 0 4 4 4 0 Phage minor structural protein GP20 CH PF00307.31 EKX49988.1 - 0.016 15.4 0.1 0.028 14.6 0.1 1.5 1 0 0 1 1 1 0 Calponin homology (CH) domain Defensin_5 PF18251.1 EKX49988.1 - 0.78 9.9 6.4 3 8.0 1.6 2.5 2 0 0 2 2 2 0 Fungal defensin Copsin Tmemb_cc2 PF10267.9 EKX49988.1 - 8 5.5 11.7 1.9 7.6 8.5 1.5 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Rtf2 PF04641.12 EKX49989.1 - 4.1e-53 180.4 5.3 5.2e-53 180.1 5.3 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.6 EKX49989.1 - 0.00069 19.5 1.0 0.0014 18.6 1.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EKX49989.1 - 0.0012 18.7 0.8 0.0022 17.8 0.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX49989.1 - 0.0015 18.4 0.9 0.0029 17.4 0.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EKX49989.1 - 0.0051 16.8 0.5 0.0051 16.8 0.5 2.4 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 EKX49989.1 - 0.022 15.1 1.6 0.96 9.8 3.1 2.4 1 1 1 2 2 2 0 Ring finger domain zf-C2HC5 PF06221.13 EKX49989.1 - 0.039 14.0 0.5 0.082 12.9 0.5 1.5 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zf-RING_6 PF14835.6 EKX49989.1 - 0.042 13.7 0.3 0.11 12.4 0.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.6 EKX49989.1 - 0.67 9.8 3.3 5.2 7.0 4.1 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Rpn3_C PF08375.11 EKX49989.1 - 1.3 9.5 0.0 1.3 9.5 0.0 2.6 2 0 0 2 2 2 0 Proteasome regulatory subunit C-terminal RWP-RK PF02042.15 EKX49990.1 - 1e-14 54.2 0.1 2.7e-14 52.9 0.1 1.7 2 0 0 2 2 2 1 RWP-RK domain HTH_8 PF02954.19 EKX49990.1 - 0.31 10.9 3.4 4.3 7.2 0.2 2.7 2 1 1 3 3 3 0 Bacterial regulatory protein, Fis family RRM_1 PF00076.22 EKX49991.1 - 4.7e-06 26.3 0.0 0.00035 20.3 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EKX49991.1 - 0.12 12.2 0.0 2 8.3 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif Radial_spoke_3 PF06098.11 EKX49992.1 - 0.081 12.2 0.3 0.098 11.9 0.3 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 WD40 PF00400.32 EKX49993.1 - 1.8e-51 171.0 21.9 1.8e-08 34.9 1.5 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX49993.1 - 1.6e-15 57.1 2.6 0.0015 18.8 0.0 6.7 2 1 5 7 7 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EKX49993.1 - 3.7e-08 32.5 2.3 0.72 8.4 0.0 5.3 1 1 3 5 5 5 4 Nucleoporin Nup120/160 FlxA PF14282.6 EKX49993.1 - 0.052 13.5 10.7 1.2 9.2 8.0 2.4 2 0 0 2 2 2 0 FlxA-like protein Ge1_WD40 PF16529.5 EKX49993.1 - 0.058 12.4 7.2 3.5 6.5 0.3 5.1 1 1 5 6 6 6 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF745 PF05335.13 EKX49993.1 - 0.085 12.6 0.3 0.085 12.6 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) FapA PF03961.13 EKX49993.1 - 0.18 10.4 4.1 0.29 9.7 4.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A zf-C4H2 PF10146.9 EKX49993.1 - 0.21 11.9 7.2 0.38 11.0 7.2 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein Cep57_CLD_2 PF14197.6 EKX49993.1 - 0.25 11.5 10.4 2.7 8.1 0.7 3.2 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Syntaxin-6_N PF09177.11 EKX49993.1 - 0.27 11.8 6.0 0.66 10.6 5.0 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4407 PF14362.6 EKX49993.1 - 0.33 10.2 6.7 0.6 9.4 6.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) KASH_CCD PF14662.6 EKX49993.1 - 0.34 10.7 10.4 0.56 10.0 10.4 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH TPR_MLP1_2 PF07926.12 EKX49993.1 - 0.49 10.5 15.1 0.98 9.5 1.2 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.19 EKX49993.1 - 0.85 7.5 9.1 1.2 6.9 9.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 EKX49993.1 - 0.88 10.2 6.9 5 7.8 2.5 2.4 2 0 0 2 2 2 0 Initiation control protein YabA APG6_N PF17675.1 EKX49993.1 - 0.99 9.9 11.2 4 8.0 11.2 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region BST2 PF16716.5 EKX49993.1 - 3.9 8.1 10.5 7.6 7.2 2.5 3.0 2 1 2 4 4 4 0 Bone marrow stromal antigen 2 Fib_alpha PF08702.10 EKX49993.1 - 4.1 7.6 6.8 2.2 8.5 3.9 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1515 PF07439.11 EKX49993.1 - 4.4 7.4 9.6 12 6.0 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) Uso1_p115_C PF04871.13 EKX49993.1 - 7.1 7.0 15.6 0.56 10.6 2.2 2.5 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region HET PF06985.11 EKX49994.1 - 2e-06 28.2 1.0 2.4e-05 24.7 1.0 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) LRR_6 PF13516.6 EKX49997.1 - 9.9e-37 121.9 17.8 3.8e-06 26.5 0.2 9.3 9 0 0 9 9 9 9 Leucine Rich repeat LRR_4 PF12799.7 EKX49997.1 - 5.8e-05 23.4 9.2 0.0048 17.3 0.0 5.1 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX49997.1 - 0.0019 18.5 2.3 47 5.1 0.1 6.5 8 0 0 8 8 8 0 Leucine Rich Repeat LRR_8 PF13855.6 EKX49997.1 - 0.0074 16.0 15.8 0.087 12.6 2.4 6.1 3 1 2 5 5 5 2 Leucine rich repeat RE_TdeIII PF09520.10 EKX49998.1 - 0.0094 15.6 4.6 0.016 14.9 3.8 1.7 1 1 0 1 1 1 1 Type II restriction endonuclease, TdeIII PurS PF02700.14 EKX49998.1 - 0.016 15.4 1.1 0.016 15.4 1.1 2.6 3 0 0 3 3 3 0 Phosphoribosylformylglycinamidine (FGAM) synthase Cep57_CLD PF14073.6 EKX49998.1 - 0.077 13.0 41.6 0.061 13.3 24.0 2.7 3 0 0 3 3 3 0 Centrosome localisation domain of Cep57 HMMR_N PF15905.5 EKX49998.1 - 0.34 10.4 46.7 0.041 13.4 12.9 2.3 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal MPS2 PF17060.5 EKX49998.1 - 0.8 8.9 21.7 0.0085 15.4 10.7 2.2 2 0 0 2 2 2 0 Monopolar spindle protein 2 DUF3450 PF11932.8 EKX49998.1 - 2 7.7 36.2 0.038 13.3 17.9 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) HAUS-augmin3 PF14932.6 EKX49998.1 - 2.9 7.4 32.7 0.36 10.4 21.2 2.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF3584 PF12128.8 EKX49998.1 - 5 4.5 36.6 0.43 8.0 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF601 PF04642.12 EKX50000.1 - 0.00084 18.9 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF601 Ion_trans PF00520.31 EKX50000.1 - 0.002 17.4 5.2 0.0033 16.7 5.2 1.4 1 0 0 1 1 1 1 Ion transport protein RRP36 PF06102.12 EKX50001.1 - 10 6.1 9.4 0.18 11.7 0.5 2.2 2 1 0 2 2 2 0 rRNA biogenesis protein RRP36 Collagen PF01391.18 EKX50003.1 - 4e-27 93.7 118.3 7.6e-09 35.2 25.0 5.1 2 1 3 5 5 5 4 Collagen triple helix repeat (20 copies) fn2 PF00040.19 EKX50003.1 - 1.1e-12 48.0 35.4 7.4e-07 29.3 8.7 3.4 3 0 0 3 3 3 3 Fibronectin type II domain Kringle PF00051.18 EKX50003.1 - 3e-05 24.2 13.1 0.12 12.6 2.0 3.3 3 0 0 3 3 3 3 Kringle domain La PF05383.17 EKX50004.1 - 8.6e-20 70.6 0.9 1.5e-19 69.8 0.9 1.4 1 0 0 1 1 1 1 La domain BATS PF06968.13 EKX50005.1 - 2.5e-20 72.4 0.1 6.1e-20 71.2 0.1 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 EKX50005.1 - 1e-10 42.2 0.0 2.2e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EKX50005.1 - 0.13 12.5 0.7 0.86 9.9 0.7 2.2 1 1 0 1 1 1 0 4Fe-4S single cluster domain Fer4_14 PF13394.6 EKX50005.1 - 0.17 12.0 0.9 0.88 9.7 0.1 2.2 2 0 0 2 2 2 0 4Fe-4S single cluster domain Arf PF00025.21 EKX50006.1 - 1e-72 243.2 0.1 1.2e-72 243.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EKX50006.1 - 9.3e-14 51.3 1.5 9.1e-10 38.2 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EKX50006.1 - 2.3e-11 43.9 0.0 3.2e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EKX50006.1 - 4.9e-11 42.4 0.0 6.4e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EKX50006.1 - 1.9e-10 40.6 0.0 2.2e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EKX50006.1 - 1.9e-08 34.0 0.0 2.3e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EKX50006.1 - 2.8e-07 30.6 0.0 4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EKX50006.1 - 0.00034 20.2 0.1 0.0035 16.9 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 EKX50006.1 - 0.012 16.2 0.0 0.041 14.4 0.0 1.8 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 EKX50006.1 - 0.012 15.5 0.0 0.58 10.1 0.0 2.1 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 EKX50006.1 - 0.098 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Hexapep PF00132.24 EKX50008.1 - 2.6e-14 52.3 8.8 2.5e-05 23.8 0.9 4.2 4 0 0 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EKX50008.1 - 0.0018 18.0 10.6 0.087 12.6 2.5 3.8 3 2 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EKX50008.1 - 0.01 14.8 1.0 0.028 13.4 0.3 1.7 1 1 1 2 2 2 0 L-fucokinase FAD_binding_3 PF01494.19 EKX50009.1 - 2.4e-22 79.7 0.0 1.3e-20 74.0 0.0 2.8 2 1 0 2 2 2 1 FAD binding domain SE PF08491.10 EKX50009.1 - 1.4e-05 24.3 0.0 0.00012 21.2 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_2 PF07992.14 EKX50009.1 - 6.2e-05 22.4 0.2 0.00034 20.0 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EKX50009.1 - 6.9e-05 22.1 0.0 9.5e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EKX50009.1 - 0.00011 22.3 1.6 0.00035 20.7 0.4 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EKX50009.1 - 0.00018 21.2 0.3 0.016 14.8 0.2 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EKX50009.1 - 0.00048 19.0 0.3 0.00074 18.3 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 EKX50009.1 - 0.00055 19.1 0.1 0.37 9.8 0.2 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.27 EKX50009.1 - 0.0024 18.4 1.0 0.0053 17.3 0.1 2.2 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EKX50009.1 - 0.06 12.6 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 EKX50009.1 - 0.063 12.5 0.5 0.1 11.8 0.5 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EKX50009.1 - 0.069 12.5 0.0 0.094 12.0 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EKX50009.1 - 0.095 12.0 0.1 7.1 5.8 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 EKX50009.1 - 0.12 11.6 0.4 0.26 10.6 0.4 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 EKX50009.1 - 0.14 11.0 1.1 2.4 6.9 0.6 2.1 1 1 1 2 2 2 0 Tryptophan halogenase Ion_trans PF00520.31 EKX50010.1 - 3.1e-26 92.1 2.9 5e-26 91.4 2.9 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX50010.1 - 0.00048 20.0 3.4 0.00048 20.0 3.4 3.1 3 1 0 3 3 3 1 Ion channel G0-G1_switch_2 PF15103.6 EKX50010.1 - 0.035 14.5 0.1 0.076 13.5 0.1 1.5 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF4446 PF14584.6 EKX50010.1 - 0.073 13.1 0.1 0.36 10.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF4199 PF13858.6 EKX50010.1 - 0.74 10.2 0.0 0.74 10.2 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) FAM178 PF14816.6 EKX50010.1 - 1.7 7.5 4.8 1 8.3 2.8 1.5 2 0 0 2 2 2 0 Family of unknown function, FAM178 EF-hand_7 PF13499.6 EKX50010.1 - 3.2 8.3 5.1 0.37 11.3 0.4 1.8 2 0 0 2 2 2 0 EF-hand domain pair Ank_4 PF13637.6 EKX50011.1 - 6.8e-17 61.6 0.6 4.7e-08 33.4 0.1 2.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX50011.1 - 2.6e-11 43.5 0.3 1.7e-05 25.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX50011.1 - 6.6e-09 36.2 0.0 8.6e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX50011.1 - 7.3e-09 35.2 0.0 0.0018 18.6 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EKX50011.1 - 4.7e-07 30.0 0.0 0.025 15.0 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EKX50012.1 - 8.7e-11 41.9 0.2 3.3e-07 30.5 0.0 2.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX50012.1 - 3.1e-10 40.4 0.6 3.3e-09 37.1 0.6 1.9 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX50012.1 - 5.4e-10 39.3 0.1 2e-07 31.1 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EKX50012.1 - 5.6e-10 39.7 0.1 8.1e-10 39.2 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX50012.1 - 5.8e-07 29.3 0.1 0.00027 21.1 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat PAS_9 PF13426.7 EKX50013.1 - 4.7e-12 46.1 0.0 5.5e-12 45.9 0.0 1.0 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EKX50013.1 - 2.2e-07 30.9 0.0 2.7e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EKX50013.1 - 7.7e-05 22.9 0.0 0.0001 22.5 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EKX50013.1 - 0.024 14.6 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 PAS domain Flavodoxin_1 PF00258.25 EKX50014.1 - 3.6e-27 95.3 0.0 7.4e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin Wyosine_form PF08608.12 EKX50014.1 - 4.4e-21 75.0 0.0 9.3e-21 74.0 0.0 1.6 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 EKX50014.1 - 4.1e-19 69.6 0.0 7.9e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_NdrI PF07972.11 EKX50014.1 - 0.00085 19.5 0.0 0.0022 18.2 0.0 1.7 1 0 0 1 1 1 1 NrdI Flavodoxin like AAA_13 PF13166.6 EKX50015.1 - 0.0028 16.4 3.8 0.0036 16.0 3.8 1.2 1 0 0 1 1 1 1 AAA domain DUF4618 PF15397.6 EKX50015.1 - 0.0033 16.9 10.7 0.011 15.2 1.8 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4618) Lzipper-MIP1 PF14389.6 EKX50015.1 - 0.0045 17.3 1.1 0.0045 17.3 1.1 2.8 3 0 0 3 3 2 1 Leucine-zipper of ternary complex factor MIP1 CobN-Mg_chel PF02514.16 EKX50015.1 - 0.01 13.7 2.3 0.0098 13.7 1.9 1.2 1 1 0 1 1 1 0 CobN/Magnesium Chelatase ABC_tran_CTD PF16326.5 EKX50015.1 - 0.048 13.9 7.1 0.52 10.6 0.7 2.8 1 1 1 2 2 2 0 ABC transporter C-terminal domain Fib_alpha PF08702.10 EKX50015.1 - 0.063 13.5 9.7 0.13 12.5 9.7 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 EKX50015.1 - 0.12 13.0 7.4 1.2 9.8 1.2 3.5 3 1 0 3 3 3 0 SlyX FapA PF03961.13 EKX50015.1 - 0.14 10.8 4.8 0.18 10.4 4.8 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A BRE1 PF08647.11 EKX50015.1 - 0.16 12.0 10.5 2.2 8.4 0.7 2.6 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF2205 PF10224.9 EKX50015.1 - 0.21 11.6 5.8 0.27 11.2 1.8 2.6 2 0 0 2 2 2 0 Short coiled-coil protein Sipho_Gp157 PF05565.11 EKX50015.1 - 0.27 11.2 5.9 0.13 12.3 3.4 1.8 2 0 0 2 2 2 0 Siphovirus Gp157 V_ATPase_I PF01496.19 EKX50015.1 - 0.28 9.0 5.1 0.38 8.6 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2968 PF11180.8 EKX50015.1 - 0.4 10.3 10.3 1.3 8.7 1.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) FliD_C PF07195.12 EKX50015.1 - 0.5 9.7 7.0 0.34 10.3 2.6 2.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF641 PF04859.12 EKX50015.1 - 0.72 10.2 12.7 69 3.8 12.7 2.5 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Phage_GP20 PF06810.11 EKX50015.1 - 0.86 9.4 7.2 1 9.2 0.2 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 JIP_LZII PF16471.5 EKX50015.1 - 2 8.7 7.8 4.3 7.6 4.3 3.1 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II DUF4200 PF13863.6 EKX50015.1 - 2 8.8 11.8 2.4 8.6 6.6 2.6 2 1 1 3 3 2 0 Domain of unknown function (DUF4200) NAD_binding_6 PF08030.12 EKX50015.1 - 2.2 8.4 7.5 15 5.7 3.2 2.4 1 1 1 2 2 2 0 Ferric reductase NAD binding domain DUF4407 PF14362.6 EKX50015.1 - 2.7 7.3 6.7 15 4.8 6.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) HIP1_clath_bdg PF16515.5 EKX50015.1 - 3.4 8.3 21.1 0.042 14.5 6.4 3.2 2 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4482 PF14818.6 EKX50015.1 - 4.1 8.3 12.1 0.25 12.2 3.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4482) Sec2p PF06428.11 EKX50015.1 - 4.2 7.4 14.1 11 6.1 1.8 3.2 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p Mto2_bdg PF12808.7 EKX50015.1 - 5.8 7.3 8.3 7.1 7.0 0.3 3.1 2 1 0 3 3 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region CCDC-167 PF15188.6 EKX50015.1 - 8.3 6.8 13.1 12 6.3 9.3 2.9 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 LMBR1 PF04791.16 EKX50015.1 - 8.4 5.2 7.3 10 4.9 7.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein LRR_6 PF13516.6 EKX50016.1 - 8.1e-14 50.4 1.7 0.0079 16.2 0.0 6.7 6 0 0 6 6 6 5 Leucine Rich repeat LRR_4 PF12799.7 EKX50016.1 - 0.0011 19.3 0.3 0.11 13.0 0.5 3.3 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) Cupin_8 PF13621.6 EKX50019.1 - 8.7e-75 251.7 0.0 1.1e-74 251.4 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EKX50019.1 - 0.0048 16.4 0.0 0.0091 15.5 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 EKX50019.1 - 0.017 15.5 0.1 0.17 12.3 0.0 2.4 3 0 0 3 3 3 0 JmjC domain, hydroxylase Sugar_tr PF00083.24 EKX50020.1 - 1.8e-42 145.8 23.1 4.8e-42 144.4 23.1 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EKX50020.1 - 9.6e-17 60.9 39.8 2.8e-14 52.8 40.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily EMG1 PF03587.14 EKX50021.1 - 1.7e-80 269.3 0.0 1.9e-80 269.1 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase EPSP_synthase PF00275.20 EKX50021.1 - 0.043 12.5 0.0 0.06 12.0 0.0 1.2 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Ank_3 PF13606.6 EKX50023.1 - 1e-07 31.6 1.4 1.1e-06 28.4 0.3 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EKX50023.1 - 3.1e-06 27.4 0.3 7.7e-06 26.1 0.3 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX50023.1 - 3.9e-06 27.1 1.2 4.3e-05 23.8 0.3 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 EKX50023.1 - 2.9e-05 24.5 0.2 8.2e-05 23.1 0.2 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX50023.1 - 0.029 15.0 0.3 3.5 8.3 0.2 3.0 3 1 0 3 3 3 0 Ankyrin repeats (many copies) WD40 PF00400.32 EKX50025.1 - 4.4e-68 223.5 22.4 3e-09 37.3 0.0 8.4 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX50025.1 - 1e-16 61.0 3.6 0.035 14.4 0.1 6.5 3 2 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 EKX50025.1 - 6.7e-12 45.8 0.0 1.2e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 EKX50025.1 - 5.4e-07 28.9 0.0 5.6 5.8 0.0 5.1 2 2 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EKX50025.1 - 2.3e-05 23.2 3.3 5.2 5.6 0.1 4.5 3 2 1 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.11 EKX50025.1 - 3.4e-05 23.8 0.0 0.0051 16.7 0.0 2.6 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 EKX50025.1 - 0.00031 19.6 0.4 0.93 8.2 0.0 3.8 3 1 1 4 4 4 1 Nup133 N terminal like Gmad1 PF10647.9 EKX50025.1 - 0.00072 19.4 0.4 0.24 11.1 0.1 2.8 2 1 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Proteasome_A_N PF10584.9 EKX50025.1 - 0.0092 15.6 0.2 14 5.5 0.0 3.8 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature PD40 PF07676.12 EKX50025.1 - 0.012 15.6 1.2 22 5.1 0.0 4.6 5 1 1 6 6 6 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 EKX50025.1 - 0.02 14.2 0.0 2.8 7.2 0.0 3.5 4 0 0 4 4 4 0 WD40-like domain Frtz PF11768.8 EKX50025.1 - 0.08 11.2 0.0 1.1 7.5 0.0 2.4 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz IKI3 PF04762.12 EKX50025.1 - 0.15 10.0 0.0 0.35 8.8 0.0 1.5 1 0 0 1 1 1 0 IKI3 family Nbas_N PF15492.6 EKX50025.1 - 0.16 11.3 2.6 25 4.1 0.2 3.8 3 1 2 5 5 5 0 Neuroblastoma-amplified sequence, N terminal Beta_helix PF13229.6 EKX50026.1 - 1e-37 129.4 37.8 2.5e-11 43.7 6.4 5.6 2 1 4 6 6 6 5 Right handed beta helix region NosD PF05048.13 EKX50026.1 - 4.9e-16 58.7 18.3 1.5e-05 24.4 3.2 5.0 1 1 3 5 5 5 5 Periplasmic copper-binding protein (NosD) CLIP_SPH_Scar PF18399.1 EKX50026.1 - 0.035 14.2 15.2 17 5.6 0.0 9.0 10 1 1 11 11 11 0 Clip-domain serine protease homolog Scarface Ctr PF04145.15 EKX50028.1 - 2.3e-26 93.2 6.4 3.8e-26 92.5 0.8 2.2 2 0 0 2 2 2 1 Ctr copper transporter family PBP1_TM PF14812.6 EKX50028.1 - 0.0039 17.5 7.8 0.0083 16.5 7.8 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DDHD PF02862.17 EKX50028.1 - 0.065 13.4 0.0 0.34 11.0 0.3 1.9 2 0 0 2 2 2 0 DDHD domain CDC45 PF02724.14 EKX50028.1 - 0.12 10.7 8.1 0.17 10.1 8.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3391 PF11871.8 EKX50028.1 - 0.13 12.9 4.5 3.2 8.3 3.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) SpoIIP PF07454.11 EKX50028.1 - 0.22 11.0 4.9 0.3 10.5 4.9 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Connexin PF00029.19 EKX50028.1 - 0.31 10.8 6.7 0.51 10.0 5.8 1.7 2 0 0 2 2 2 0 Connexin DNA_pol_phi PF04931.13 EKX50028.1 - 0.43 8.6 10.5 0.63 8.1 10.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi Pes-10 PF07149.11 EKX50028.1 - 0.54 9.3 10.2 0.85 8.6 10.2 1.3 1 0 0 1 1 1 0 Pes-10 DUF913 PF06025.12 EKX50028.1 - 0.62 9.0 2.8 1.1 8.2 2.8 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RRN3 PF05327.11 EKX50028.1 - 1.1 7.8 7.4 1.7 7.1 7.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GCIP PF13324.6 EKX50028.1 - 1.2 8.7 7.4 0.83 9.2 4.1 2.1 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting CPSF100_C PF13299.6 EKX50028.1 - 1.5 8.9 8.6 0.43 10.7 5.7 1.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RPN2_C PF18004.1 EKX50028.1 - 4.1 7.3 17.7 8.3 6.3 17.7 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain TRAP_alpha PF03896.16 EKX50028.1 - 4.6 6.4 6.1 8.4 5.5 6.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PAS_3 PF08447.12 EKX50029.1 - 3.5e-08 33.6 0.0 6.5e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EKX50029.1 - 1.3e-06 28.4 1.0 1.6e-05 24.9 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 EKX50029.1 - 0.00026 21.2 0.1 0.00078 19.7 0.0 1.8 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 EKX50029.1 - 0.003 17.8 0.2 0.014 15.6 0.0 2.1 2 0 0 2 2 2 1 PAS fold Spt5_N PF11942.8 EKX50029.1 - 0.012 16.5 4.5 0.029 15.4 4.5 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal PAS_11 PF14598.6 EKX50029.1 - 0.079 13.1 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 PAS domain PhnA PF03831.14 EKX50029.1 - 0.2 11.6 0.0 0.4 10.6 0.0 1.4 1 0 0 1 1 1 0 PhnA domain Pecanex_C PF05041.15 EKX50031.1 - 4.5e-16 59.1 0.1 7.1e-16 58.5 0.1 1.2 1 0 0 1 1 1 1 Pecanex protein (C-terminus) BLM_N PF16202.5 EKX50032.1 - 0.064 12.4 0.1 0.085 12.0 0.1 1.1 1 0 0 1 1 1 0 N-terminal region of Bloom syndrome protein MORN PF02493.20 EKX50034.1 - 2.1e-22 77.6 17.0 2.2e-07 30.3 0.4 4.5 4 0 0 4 4 4 4 MORN repeat AAA PF00004.29 EKX50035.1 - 1.8e-42 144.9 0.0 2.3e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EKX50035.1 - 2.4e-07 31.1 0.0 0.00018 21.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EKX50035.1 - 2.4e-06 28.1 0.0 0.0017 18.7 0.0 2.3 1 1 1 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 EKX50035.1 - 3.9e-05 23.5 0.0 8.5e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EKX50035.1 - 5e-05 23.1 0.0 6.9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 EKX50035.1 - 5.2e-05 22.6 0.1 0.00011 21.5 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 EKX50035.1 - 0.0002 21.4 0.1 0.00099 19.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EKX50035.1 - 0.00042 20.9 0.0 0.00072 20.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EKX50035.1 - 0.00046 20.4 0.0 0.00067 19.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EKX50035.1 - 0.0009 18.7 0.1 0.0015 18.0 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 EKX50035.1 - 0.001 19.2 0.0 0.0035 17.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 EKX50035.1 - 0.0014 18.4 0.0 0.0036 17.0 0.0 1.6 1 1 1 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.6 EKX50035.1 - 0.0019 17.8 0.2 0.1 12.1 0.2 2.1 1 1 1 2 2 2 1 AAA domain NACHT PF05729.12 EKX50035.1 - 0.0041 17.1 0.0 0.036 14.0 0.0 2.1 1 1 0 1 1 1 1 NACHT domain AAA_28 PF13521.6 EKX50035.1 - 0.0084 16.4 0.0 0.01 16.1 0.0 1.3 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EKX50035.1 - 0.01 15.0 0.0 0.044 13.0 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 EKX50035.1 - 0.013 15.6 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 EKX50035.1 - 0.019 14.4 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 EKX50035.1 - 0.024 14.6 0.0 0.036 14.1 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EKX50035.1 - 0.026 14.9 0.0 0.068 13.6 0.0 1.8 2 0 0 2 2 1 0 RNA helicase Parvo_NS1 PF01057.17 EKX50035.1 - 0.029 13.4 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 EKX50035.1 - 0.041 13.6 0.0 0.1 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EKX50035.1 - 0.058 13.8 0.0 0.096 13.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EKX50035.1 - 0.065 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ATPase PF06745.13 EKX50035.1 - 0.077 12.3 0.0 0.19 11.1 0.0 1.7 2 0 0 2 2 2 0 KaiC CPT PF07931.12 EKX50035.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_7 PF12775.7 EKX50035.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_19 PF13245.6 EKX50035.1 - 0.13 12.6 0.2 0.4 11.0 0.1 1.7 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.9 EKX50035.1 - 0.25 10.5 0.0 0.45 9.7 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Peptidase_M16_C PF05193.21 EKX50036.1 - 1.7e-13 51.0 0.0 1.6e-11 44.5 0.0 2.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EKX50036.1 - 1.4e-10 41.3 0.0 6.5e-10 39.2 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 EKX50036.1 - 0.019 14.1 0.3 4.3 6.4 0.6 2.5 2 0 0 2 2 2 0 Peptidase M16C associated Mating_N PF12731.7 EKX50036.1 - 0.12 12.5 2.4 4.8 7.3 0.0 2.9 3 0 0 3 3 3 0 Mating-type protein beta 1 DUF2913 PF11140.8 EKX50036.1 - 0.18 11.5 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) Peptidase_M48 PF01435.18 EKX50037.1 - 5.3e-19 68.8 0.2 1.1e-17 64.5 0.2 2.0 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 EKX50037.1 - 0.00041 19.6 0.6 0.00077 18.7 0.6 1.5 1 1 0 1 1 1 1 BlaR1 peptidase M56 Peptidase_M78 PF06114.13 EKX50037.1 - 0.076 12.9 0.1 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 IrrE N-terminal-like domain Pentapeptide PF00805.22 EKX50038.1 - 2.2e-211 682.2 205.7 3.7e-13 48.8 1.1 29.9 12 7 9 30 30 30 28 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 EKX50038.1 - 9.8e-124 403.8 65.8 5.8e-13 48.8 2.5 15.9 5 3 12 18 18 18 18 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 EKX50038.1 - 3.3e-99 324.9 64.6 1.2e-07 31.8 2.2 25.1 11 9 15 27 27 27 26 Pentapeptide repeats (9 copies) CfAFP PF05264.11 EKX50038.1 - 1.2e-06 28.5 39.6 0.057 13.4 2.2 10.6 4 3 7 12 12 12 4 Choristoneura fumiferana antifreeze protein (CfAFP) CBM_5_12_2 PF14600.6 EKX50038.1 - 0.0018 18.1 0.1 8 6.5 0.0 5.7 5 0 0 5 5 5 1 Cellulose-binding domain OprD PF03573.13 EKX50038.1 - 0.29 10.1 3.6 32 3.4 0.1 5.4 6 1 1 7 7 7 0 outer membrane porin, OprD family RskA PF10099.9 EKX50039.1 - 0.00095 19.5 4.0 0.00095 19.5 4.0 2.6 2 1 0 2 2 2 1 Anti-sigma-K factor rskA HAS-barrel PF09378.10 EKX50039.1 - 0.44 10.7 0.0 0.44 10.7 0.0 3.3 4 1 0 4 4 4 0 HAS barrel domain Carb_anhydrase PF00194.21 EKX50040.1 - 6.3e-29 101.3 0.0 1.1e-28 100.5 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase PDZ PF00595.24 EKX50041.1 - 2.7e-07 30.8 0.2 5.6e-07 29.8 0.2 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX50041.1 - 7.9e-06 26.1 0.1 1.7e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 PDZ domain TSC22 PF01166.18 EKX50041.1 - 0.00021 21.5 3.5 0.008 16.5 0.4 2.7 2 0 0 2 2 2 1 TSC-22/dip/bun family bZIP_1 PF00170.21 EKX50041.1 - 0.00045 20.3 10.0 0.028 14.5 0.6 3.0 2 1 1 3 3 3 2 bZIP transcription factor PDZ_6 PF17820.1 EKX50041.1 - 0.00052 19.8 0.1 0.00094 19.0 0.1 1.5 1 0 0 1 1 1 1 PDZ domain TMF_TATA_bd PF12325.8 EKX50041.1 - 0.0013 19.0 2.0 0.0022 18.2 2.0 1.3 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding YabA PF06156.13 EKX50041.1 - 0.0014 19.2 5.9 0.047 14.3 5.9 2.3 1 1 0 1 1 1 1 Initiation control protein YabA ATG16 PF08614.11 EKX50041.1 - 0.003 17.8 6.1 0.0053 17.0 6.1 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) FPP PF05911.11 EKX50041.1 - 0.0037 15.5 0.8 0.005 15.1 0.8 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil HALZ PF02183.18 EKX50041.1 - 0.0077 16.4 7.1 0.47 10.7 1.7 2.6 2 0 0 2 2 2 2 Homeobox associated leucine zipper GAS PF13851.6 EKX50041.1 - 0.0078 15.6 7.5 0.013 14.9 7.5 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding MscS_porin PF12795.7 EKX50041.1 - 0.017 14.7 3.5 0.055 13.0 0.2 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain CENP-H PF05837.12 EKX50041.1 - 0.022 15.2 2.0 0.041 14.3 2.0 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) V_ATPase_I PF01496.19 EKX50041.1 - 0.032 12.2 0.9 0.043 11.7 0.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FapA PF03961.13 EKX50041.1 - 0.06 11.9 0.7 0.085 11.5 0.7 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc7 PF08317.11 EKX50041.1 - 0.073 11.9 2.2 0.12 11.2 2.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein EzrA PF06160.12 EKX50041.1 - 0.085 11.0 1.6 0.38 8.9 1.9 1.6 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Tropomyosin_1 PF12718.7 EKX50041.1 - 0.097 12.8 7.2 0.16 12.1 7.2 1.3 1 0 0 1 1 1 0 Tropomyosin like Nup54 PF13874.6 EKX50041.1 - 0.12 12.5 0.4 0.22 11.6 0.4 1.4 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 KASH_CCD PF14662.6 EKX50041.1 - 0.13 12.1 6.3 0.49 10.2 6.3 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH bZIP_2 PF07716.15 EKX50041.1 - 0.13 12.4 7.7 1.3 9.2 0.4 2.7 3 0 0 3 3 2 0 Basic region leucine zipper TACC_C PF05010.14 EKX50041.1 - 0.15 11.8 5.3 0.32 10.7 1.2 2.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal SlyX PF04102.12 EKX50041.1 - 0.18 12.4 1.7 1.5 9.5 1.7 2.4 1 1 0 1 1 1 0 SlyX BRE1 PF08647.11 EKX50041.1 - 0.19 11.8 6.2 0.34 11.0 6.2 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Shugoshin_N PF07558.11 EKX50041.1 - 0.23 11.4 9.3 0.56 10.1 2.0 2.9 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Syntaxin-6_N PF09177.11 EKX50041.1 - 0.27 11.8 2.4 1 9.9 2.4 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal HIP1_clath_bdg PF16515.5 EKX50041.1 - 0.4 11.3 2.7 0.55 10.9 1.2 2.0 2 0 0 2 2 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6_N PF17675.1 EKX50041.1 - 0.45 11.1 6.7 1.1 9.8 6.7 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 EKX50041.1 - 0.66 9.8 2.6 22 4.9 0.1 2.4 1 1 1 2 2 2 0 Septum formation initiator Lebercilin PF15619.6 EKX50041.1 - 0.67 9.6 10.6 2 8.1 0.7 2.2 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease ZapB PF06005.12 EKX50041.1 - 0.72 10.3 3.9 12 6.5 0.1 2.4 2 0 0 2 2 2 0 Cell division protein ZapB Prefoldin_2 PF01920.20 EKX50041.1 - 0.84 9.6 4.3 4.6 7.3 1.4 2.4 2 0 0 2 2 2 0 Prefoldin subunit HAP1_N PF04849.13 EKX50041.1 - 1.1 8.4 8.6 1.4 8.1 2.9 2.1 1 1 1 2 2 2 0 HAP1 N-terminal conserved region KIAA1430 PF13879.6 EKX50041.1 - 1.3 9.8 4.8 3.1 8.6 4.8 1.6 1 0 0 1 1 1 0 KIAA1430 homologue Ax_dynein_light PF10211.9 EKX50041.1 - 2 8.3 5.9 9.9 6.1 1.6 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain TMF_DNA_bd PF12329.8 EKX50041.1 - 2 8.5 8.1 0.38 10.8 0.8 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding XhlA PF10779.9 EKX50041.1 - 2.4 8.4 7.6 1.4 9.2 2.4 2.6 2 0 0 2 2 2 0 Haemolysin XhlA C2 PF00168.30 EKX50042.1 - 2.5e-21 75.9 0.0 5.2e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain cNMP_binding PF00027.29 EKX50042.1 - 1.9e-07 31.1 0.2 2.6 8.2 0.0 4.4 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain AvrM-A PF18241.1 EKX50043.1 - 0.11 13.0 2.9 0.25 11.7 2.9 1.5 1 0 0 1 1 1 0 Flax-rust effector AvrM-A TP_methylase PF00590.20 EKX50044.1 - 3.3e-29 102.4 0.2 5.8e-29 101.6 0.2 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF374 PF04028.13 EKX50044.1 - 0.028 14.0 0.4 0.31 10.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF374) Abhydrolase_1 PF00561.20 EKX50045.1 - 9.5e-05 22.2 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EKX50045.1 - 0.00068 19.0 0.0 0.00088 18.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EKX50045.1 - 0.047 14.3 0.0 0.07 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ndr PF03096.14 EKX50045.1 - 0.064 11.9 0.0 0.075 11.7 0.0 1.2 1 0 0 1 1 1 0 Ndr family TPR_1 PF00515.28 EKX50046.1 - 3.8e-42 140.4 8.8 7.2e-06 25.6 0.4 9.7 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 EKX50046.1 - 3.4e-40 132.9 10.4 7.4e-05 22.6 0.6 10.1 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.6 EKX50046.1 - 4.1e-27 93.6 6.6 0.00026 20.6 0.1 9.8 6 4 4 10 10 10 7 TPR repeat TPR_8 PF13181.6 EKX50046.1 - 1.9e-26 90.0 2.4 0.0011 19.0 0.2 9.4 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 EKX50046.1 - 6.4e-24 84.3 3.0 6.4e-06 26.7 0.4 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 EKX50046.1 - 2.8e-23 81.8 6.5 2.8e-06 27.4 0.1 6.7 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 EKX50046.1 - 1.3e-22 79.8 16.4 8e-08 32.5 0.0 6.4 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 EKX50046.1 - 9e-21 74.2 4.0 0.00051 20.5 0.0 7.2 5 3 2 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 EKX50046.1 - 3.4e-19 67.9 11.3 0.017 15.9 0.1 9.2 5 1 4 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 EKX50046.1 - 3.3e-16 58.4 5.2 0.035 14.5 0.0 9.1 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_15 PF13429.6 EKX50046.1 - 7.7e-12 45.0 2.1 0.065 12.4 0.3 5.2 2 1 3 5 5 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX50046.1 - 4.7e-10 39.6 6.4 0.31 11.3 0.0 6.0 3 1 3 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 EKX50046.1 - 1.4e-07 30.8 3.4 0.083 11.8 0.1 4.8 2 1 2 5 5 5 2 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 EKX50046.1 - 9.7e-05 22.8 10.0 5.1 8.0 0.1 8.0 9 0 0 9 9 9 1 Tetratricopeptide repeat SNAP PF14938.6 EKX50046.1 - 0.00019 21.0 4.8 0.67 9.3 0.1 4.5 2 1 1 4 4 4 2 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 EKX50046.1 - 0.0003 20.6 10.0 0.53 10.2 0.0 5.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX50046.1 - 0.00034 20.4 12.1 1.9 8.7 0.0 8.0 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_20 PF14561.6 EKX50046.1 - 0.0026 18.1 4.7 0.79 10.1 0.0 4.9 4 1 2 6 6 6 1 Tetratricopeptide repeat NTase_sub_bind PF08780.11 EKX50046.1 - 0.0093 15.9 0.3 26 4.8 0.0 4.7 4 1 1 5 5 5 0 Nucleotidyltransferase substrate binding protein like Alkyl_sulf_dimr PF14863.6 EKX50046.1 - 0.015 15.8 2.1 7.2 7.1 0.2 4.1 2 1 1 3 3 3 0 Alkyl sulfatase dimerisation DASH_Hsk3 PF08227.11 EKX50046.1 - 0.078 13.4 0.1 0.4 11.1 0.0 2.2 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like MIT PF04212.18 EKX50046.1 - 1.3 9.1 12.7 59 3.8 0.3 7.2 8 3 0 8 8 8 0 MIT (microtubule interacting and transport) domain BTAD PF03704.17 EKX50046.1 - 2.7 8.4 6.6 11 6.5 0.0 4.6 4 2 0 4 4 3 0 Bacterial transcriptional activator domain Hydrolase_4 PF12146.8 EKX50047.1 - 7.2e-07 28.7 0.0 1.5e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EKX50047.1 - 1.3e-05 25.0 0.2 0.0062 16.2 0.2 2.8 2 1 0 2 2 2 2 alpha/beta hydrolase fold E1-E2_ATPase PF00122.20 EKX50048.1 - 6.4e-16 58.4 0.4 2.9e-12 46.5 0.0 3.2 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.26 EKX50048.1 - 6.6e-08 33.1 0.2 0.009 16.3 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EKX50048.1 - 2e-07 31.0 0.0 4.4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) 7tm_6 PF02949.20 EKX50048.1 - 0.018 14.2 1.9 0.025 13.6 0.1 2.2 2 0 0 2 2 2 0 7tm Odorant receptor DUF3290 PF11694.8 EKX50048.1 - 2 8.4 5.4 7.4 6.5 1.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) YlaH PF14036.6 EKX50048.1 - 2.5 8.5 6.2 0.33 11.3 0.5 2.6 2 0 0 2 2 2 0 YlaH-like protein Exo_endo_phos PF03372.23 EKX50049.1 - 3.3e-21 75.9 0.0 2.3e-20 73.1 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MYT1 PF08474.11 EKX50050.1 - 0.022 14.7 0.2 0.027 14.4 0.2 1.2 1 0 0 1 1 1 0 Myelin transcription factor 1 Med4 PF10018.9 EKX50051.1 - 1.8e-06 27.8 0.2 4.2e-06 26.6 0.2 1.7 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Beta_helix PF13229.6 EKX50052.1 - 2.3e-65 219.3 50.1 3.9e-20 72.3 7.4 5.0 1 1 4 5 5 5 5 Right handed beta helix region NosD PF05048.13 EKX50052.1 - 9.3e-41 139.7 14.8 1.4e-14 54.0 0.7 4.5 1 1 3 4 4 4 4 Periplasmic copper-binding protein (NosD) TBCA PF02970.16 EKX50053.1 - 0.012 16.0 6.2 0.012 16.0 6.2 2.5 2 1 0 2 2 2 0 Tubulin binding cofactor A HALZ PF02183.18 EKX50053.1 - 0.013 15.8 3.3 0.013 15.8 3.3 2.7 2 2 1 3 3 3 0 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.12 EKX50053.1 - 0.057 13.5 18.0 0.27 11.3 5.6 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 EKX50053.1 - 0.065 13.3 5.2 0.07 13.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) AAA_27 PF13514.6 EKX50053.1 - 0.083 12.5 5.8 0.15 11.6 5.7 1.5 1 1 0 1 1 1 0 AAA domain FlaC_arch PF05377.11 EKX50053.1 - 0.086 13.2 3.4 0.58 10.6 0.4 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Lectin_N PF03954.14 EKX50053.1 - 0.28 10.9 7.3 3.9 7.2 0.6 2.3 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Spc7 PF08317.11 EKX50053.1 - 0.38 9.6 20.3 0.12 11.3 8.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein BBP1_C PF15272.6 EKX50053.1 - 0.82 9.5 14.3 0.39 10.5 4.6 2.1 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal DUF4407 PF14362.6 EKX50053.1 - 1.4 8.2 7.4 4 6.7 7.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF812 PF05667.11 EKX50053.1 - 1.7 7.5 14.6 2.4 6.9 14.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Siah-Interact_N PF09032.11 EKX50053.1 - 1.7 9.0 10.1 5 7.5 2.7 3.0 2 1 1 3 3 3 0 Siah interacting protein, N terminal Prominin PF05478.11 EKX50053.1 - 2.3 6.1 6.8 3.1 5.6 6.8 1.1 1 0 0 1 1 1 0 Prominin TMPIT PF07851.13 EKX50053.1 - 3 7.0 9.5 5.3 6.2 1.3 2.1 2 0 0 2 2 2 0 TMPIT-like protein YabA PF06156.13 EKX50053.1 - 5.4 7.7 16.5 0.082 13.5 4.9 2.4 2 1 0 2 2 2 0 Initiation control protein YabA FAM76 PF16046.5 EKX50053.1 - 7.8 5.8 9.1 2.3 7.5 3.4 2.0 2 0 0 2 2 2 0 FAM76 protein APG6_N PF17675.1 EKX50053.1 - 9.8 6.7 35.0 1.4 9.4 17.3 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region Syja_N PF02383.18 EKX50054.1 - 8.3e-40 137.0 0.0 1.2e-39 136.5 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 EKX50054.1 - 0.0001 21.9 0.0 0.00018 21.1 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Syja_N PF02383.18 EKX50055.1 - 1.1e-60 205.6 0.0 5.2e-60 203.4 0.0 1.9 1 1 0 1 1 1 1 SacI homology domain PDZ_6 PF17820.1 EKX50055.1 - 5.8e-13 48.5 0.0 1.1e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX50055.1 - 1.6e-05 25.2 0.3 3.7e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX50055.1 - 2.3e-05 24.6 0.0 4.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX50055.1 - 0.0044 17.0 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 Tricorn protease PDZ domain Clat_adaptor_s PF01217.20 EKX50056.1 - 2.9e-55 186.1 3.9 3.2e-55 185.9 3.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain polyprenyl_synt PF00348.17 EKX50057.1 - 1e-69 234.4 0.1 1.3e-69 234.2 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 EKX50057.1 - 0.086 12.4 0.3 0.14 11.8 0.3 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 EF-hand_5 PF13202.6 EKX50059.1 - 0.00031 20.1 0.0 0.0011 18.3 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 EKX50059.1 - 0.022 14.3 0.0 0.067 12.8 0.0 1.9 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 EKX50059.1 - 0.044 13.7 0.0 1 9.5 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain Glycophorin_A PF01102.18 EKX50059.1 - 0.044 14.0 0.2 0.097 12.9 0.2 1.5 1 0 0 1 1 1 0 Glycophorin A EF-hand_7 PF13499.6 EKX50059.1 - 0.065 13.7 0.0 0.42 11.1 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair DUF5048 PF16467.5 EKX50061.1 - 0.0001 22.5 11.4 1.7 9.0 0.1 3.9 1 1 3 4 4 4 3 Domain of unknown function (DUF5048) ChW PF07538.11 EKX50061.1 - 0.036 14.0 12.7 1.8e+04 -5.3 12.7 6.6 1 1 0 1 1 1 0 Clostridial hydrophobic W DnaA_N PF11638.8 EKX50061.1 - 0.057 13.2 22.8 32 4.4 0.8 7.4 1 1 7 8 8 8 0 DnaA N-terminal domain EXOSC1 PF10447.9 EKX50061.1 - 0.14 12.8 1.1 31 5.2 0.1 3.0 1 1 3 4 4 4 0 Exosome component EXOSC1/CSL4 Med31 PF05669.12 EKX50061.1 - 0.52 10.3 4.5 14 5.7 0.3 2.6 1 1 2 3 3 3 0 SOH1 DUF4219 PF13961.6 EKX50061.1 - 1.5 8.6 59.6 7.8 6.3 0.9 8.8 9 0 0 9 9 9 0 Domain of unknown function (DUF4219) HAD_2 PF13419.6 EKX50062.1 - 0.014 15.4 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Adeno_IVa2 PF02456.15 EKX50062.1 - 0.037 12.8 0.1 0.35 9.6 0.0 2.0 1 1 1 2 2 2 0 Adenovirus IVa2 protein Exo_endo_phos PF03372.23 EKX50063.1 - 5.4e-06 26.1 0.0 2e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peripla_BP_4 PF13407.6 EKX50063.1 - 0.071 12.7 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein domain Tubulin PF00091.25 EKX50064.1 - 1.9e-28 100.0 0.0 1.1e-27 97.5 0.0 1.9 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 EKX50064.1 - 0.092 11.9 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 Tubulin like Mlf1IP PF10248.9 EKX50065.1 - 4.3e-15 56.1 2.9 5.6e-15 55.7 2.9 1.1 1 0 0 1 1 1 1 Myelodysplasia-myeloid leukemia factor 1-interacting protein HA PF03457.14 EKX50066.1 - 0.093 13.1 1.3 0.19 12.1 1.3 1.5 1 0 0 1 1 1 0 Helicase associated domain LRS4 PF10422.9 EKX50066.1 - 7.7 6.0 11.7 32 4.0 11.7 1.9 1 1 0 1 1 1 0 Monopolin complex subunit LRS4 Prefoldin_2 PF01920.20 EKX50068.1 - 3.6e-12 46.2 3.7 4.7e-12 45.8 3.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit TPR_MLP1_2 PF07926.12 EKX50068.1 - 0.00097 19.2 2.3 0.00097 19.2 2.3 2.1 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 EKX50068.1 - 0.11 12.7 5.9 0.44 10.8 1.2 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Spc24 PF08286.11 EKX50068.1 - 0.85 9.9 4.6 0.6 10.4 1.3 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 LRR_9 PF14580.6 EKX50069.1 - 3.6e-64 215.4 50.3 4.3e-15 55.7 5.6 8.9 4 3 4 9 9 9 8 Leucine-rich repeat LRR_4 PF12799.7 EKX50069.1 - 1.6e-48 161.8 115.4 2.1e-06 28.0 1.6 16.0 8 5 9 19 19 19 18 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX50069.1 - 2.9e-39 132.6 92.3 1.5e-06 27.9 0.0 13.4 8 4 2 12 12 12 12 Leucine rich repeat Sld5 PF05916.11 EKX50073.1 - 1.5e-12 48.0 0.8 2.2e-12 47.4 0.8 1.3 1 0 0 1 1 1 1 GINS complex protein Peptidase_S9 PF00326.21 EKX50074.1 - 6.4e-08 32.3 0.0 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EKX50074.1 - 0.0062 16.4 0.0 0.013 15.3 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EKX50074.1 - 0.01 15.5 0.2 0.018 14.7 0.2 1.5 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 EKX50074.1 - 0.013 14.8 0.1 0.82 8.9 0.2 2.3 1 1 0 2 2 2 0 Serine aminopeptidase, S33 Esterase_phd PF10503.9 EKX50074.1 - 0.016 14.7 0.6 0.037 13.5 0.6 1.5 1 0 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_6 PF12697.7 EKX50074.1 - 0.15 12.6 9.8 0.89 10.1 6.4 3.0 2 1 0 2 2 2 0 Alpha/beta hydrolase family SAM_1 PF00536.30 EKX50076.1 - 0.012 16.1 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF1743 PF08489.11 EKX50076.1 - 0.08 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1743) DUF1980 PF09323.10 EKX50077.1 - 1.3 8.9 7.1 0.24 11.3 3.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) PP2C PF00481.21 EKX50078.1 - 3.8e-31 108.7 0.2 2.1e-30 106.2 0.2 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C Mago-bind PF09282.10 EKX50078.1 - 7.7e-11 41.7 0.2 1.5e-10 40.7 0.2 1.5 1 0 0 1 1 1 1 Mago binding PP2C_2 PF13672.6 EKX50078.1 - 1.7e-06 27.8 0.0 3.6e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EKX50078.1 - 0.0046 16.9 0.0 0.78 9.6 0.1 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Spidroin_N PF16763.5 EKX50078.1 - 0.18 11.8 0.8 0.93 9.5 0.4 2.1 2 0 0 2 2 2 0 Major ampullate spidroin 1, spider silk protein 1, N-term MFS_1 PF07690.16 EKX50079.1 - 2.8e-07 29.8 36.3 0.00054 19.0 16.3 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Lon_C PF05362.13 EKX50080.1 - 1.2e-75 253.6 0.6 1.6e-74 249.9 0.3 2.2 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 EKX50080.1 - 1.4e-21 77.3 0.0 2.6e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 EKX50080.1 - 1.4e-08 34.6 0.4 3.3e-08 33.4 0.4 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 EKX50080.1 - 5.4e-07 29.7 0.0 1.1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EKX50080.1 - 8.1e-07 29.3 0.0 1.8e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EKX50080.1 - 0.00019 21.2 0.0 0.0042 16.8 0.0 2.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EKX50080.1 - 0.0037 17.5 0.0 0.24 11.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EKX50080.1 - 0.0038 17.8 0.0 0.0083 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EKX50080.1 - 0.0039 16.4 0.1 0.0079 15.4 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 EKX50080.1 - 0.0046 17.3 0.0 0.021 15.2 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_PrkA PF08298.11 EKX50080.1 - 0.0051 15.8 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RsgA_GTPase PF03193.16 EKX50080.1 - 0.0091 15.9 1.1 0.087 12.7 0.0 2.5 3 0 0 3 3 3 1 RsgA GTPase AAA_14 PF13173.6 EKX50080.1 - 0.011 15.7 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EKX50080.1 - 0.013 16.0 0.0 0.028 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain SKI PF01202.22 EKX50080.1 - 0.016 15.3 0.1 0.036 14.2 0.1 1.6 1 0 0 1 1 1 0 Shikimate kinase IstB_IS21 PF01695.17 EKX50080.1 - 0.019 14.7 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 EKX50080.1 - 0.03 14.7 0.0 0.079 13.4 0.0 1.8 1 1 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 EKX50080.1 - 0.048 13.6 0.1 1.3 8.9 0.0 2.5 1 1 1 2 2 2 0 NTPase AAA_30 PF13604.6 EKX50080.1 - 0.079 12.7 0.0 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 EKX50080.1 - 0.11 12.4 0.0 0.3 10.9 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ELO PF01151.18 EKX50081.1 - 5.8e-54 183.3 18.4 6.9e-54 183.0 18.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family RRM_1 PF00076.22 EKX50082.1 - 8.3e-12 44.8 11.3 0.00064 19.5 0.0 5.3 4 2 2 6 6 6 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EKX50082.1 - 0.00036 20.6 0.4 0.01 15.9 0.0 2.9 2 1 1 3 3 3 1 RNA recognition motif Nup35_RRM PF05172.13 EKX50082.1 - 0.013 15.4 0.0 0.3 11.1 0.1 2.4 1 1 1 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 EKX50082.1 - 0.02 14.7 0.0 0.02 14.7 0.0 3.1 4 0 0 4 4 4 0 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 EKX50082.1 - 0.048 13.7 0.0 0.18 11.9 0.0 2.0 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF4746 PF15928.5 EKX50082.1 - 0.27 10.6 6.8 0.56 9.6 6.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TFIIE-A_C PF11521.8 EKX50082.1 - 1.1 9.6 11.0 1.3e+02 3.0 11.0 2.8 1 1 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha FAM176 PF14851.6 EKX50082.1 - 2 8.1 6.9 3.1 7.5 5.6 2.1 2 0 0 2 2 2 0 FAM176 family AAA PF00004.29 EKX50084.1 - 8.5e-26 90.9 0.0 1.8e-15 57.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX50084.1 - 3.5e-07 30.7 0.0 2.3e-05 24.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_lid_3 PF17862.1 EKX50084.1 - 1.1e-06 28.4 0.7 1.1e-05 25.1 0.1 2.7 3 0 0 3 3 3 1 AAA+ lid domain AAA_5 PF07728.14 EKX50084.1 - 0.0013 18.8 0.0 0.0044 17.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EKX50084.1 - 0.0013 19.2 0.0 0.0052 17.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EKX50084.1 - 0.0017 18.6 0.1 0.024 14.9 0.0 2.7 2 2 1 3 3 3 1 AAA domain AAA_33 PF13671.6 EKX50084.1 - 0.0021 18.2 0.0 0.0044 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EKX50084.1 - 0.0033 17.3 0.0 0.0076 16.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain RuvB_N PF05496.12 EKX50084.1 - 0.0034 17.2 0.0 0.0076 16.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 EKX50084.1 - 0.0079 15.8 0.0 1.7 8.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 EKX50084.1 - 0.012 15.7 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EKX50084.1 - 0.017 14.4 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.11 EKX50084.1 - 0.021 14.7 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EKX50084.1 - 0.028 14.7 0.0 0.084 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EKX50084.1 - 0.029 14.7 0.0 0.074 13.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 EKX50084.1 - 0.029 14.1 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EKX50084.1 - 0.04 13.8 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.6 EKX50084.1 - 0.043 14.1 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EKX50084.1 - 0.048 13.6 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_14 PF13173.6 EKX50084.1 - 0.068 13.2 0.0 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EKX50084.1 - 0.071 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 EKX50084.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 EKX50084.1 - 0.16 11.2 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Ribosomal_L29e PF01779.17 EKX50085.1 - 3.4e-17 62.5 13.5 6e-17 61.7 13.5 1.4 1 0 0 1 1 1 1 Ribosomal L29e protein family PA28_beta PF02252.18 EKX50086.1 - 3.6e-51 172.6 0.3 5.4e-51 172.1 0.3 1.2 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit tRNA-synt_1d PF00750.19 EKX50087.1 - 1.9e-125 418.5 0.0 2.4e-125 418.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EKX50087.1 - 5.5e-29 100.8 0.1 1.1e-28 99.8 0.1 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EKX50087.1 - 2.6e-21 76.0 0.0 1.1e-20 74.0 0.0 2.0 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1 PF00133.22 EKX50087.1 - 0.0065 14.8 0.0 0.01 14.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EKX50087.1 - 0.027 13.2 0.0 0.046 12.5 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (M) tRNA-synt_1d PF00750.19 EKX50088.1 - 1.8e-125 418.5 0.0 2.3e-125 418.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EKX50088.1 - 4.9e-29 100.9 0.1 9.7e-29 100.0 0.1 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EKX50088.1 - 2.2e-21 76.2 0.0 9.6e-21 74.2 0.0 2.1 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1 PF00133.22 EKX50088.1 - 0.0058 14.9 0.0 0.0095 14.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EKX50088.1 - 0.024 13.4 0.0 0.042 12.6 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (M) Ribosomal_L22e PF01776.17 EKX50089.1 - 3.8e-07 30.4 0.8 1.8e-06 28.3 0.4 2.4 2 1 0 2 2 2 1 Ribosomal L22e protein family EF_assoc_1 PF08355.12 EKX50089.1 - 0.056 13.0 0.0 0.19 11.3 0.0 1.9 1 0 0 1 1 1 0 EF hand associated Ribosomal_L22e PF01776.17 EKX50090.1 - 1e-16 61.3 0.3 1.2e-16 61.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family WD40 PF00400.32 EKX50092.1 - 5.3e-40 134.7 22.8 3.4e-08 34.0 0.3 5.0 5 0 0 5 5 5 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 EKX50092.1 - 3.5e-07 29.1 0.5 0.0015 17.1 0.1 2.0 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.8 EKX50092.1 - 6e-06 25.2 5.3 0.56 8.8 0.0 4.0 1 1 3 4 4 4 4 Nucleoporin Nup120/160 WD40_like PF17005.5 EKX50092.1 - 0.00013 21.5 0.0 0.0078 15.6 0.0 2.6 1 1 1 2 2 2 2 WD40-like domain VID27 PF08553.10 EKX50092.1 - 0.00073 18.7 0.2 0.16 11.0 0.0 2.3 2 1 0 2 2 2 2 VID27 C-terminal WD40-like domain Bactofilin PF04519.13 EKX50092.1 - 0.0031 17.8 0.3 3.7 7.9 0.1 3.2 1 1 2 3 3 3 1 Polymer-forming cytoskeletal OCD_Mu_crystall PF02423.15 EKX50092.1 - 0.0079 15.2 0.0 2.3 7.1 0.0 2.9 2 1 1 3 3 3 1 Ornithine cyclodeaminase/mu-crystallin family CopK PF11525.8 EKX50092.1 - 0.021 14.4 0.0 3.1 7.5 0.0 3.5 5 0 0 5 5 5 0 Copper resistance protein K Bacteriocin_IIi PF11758.8 EKX50092.1 - 4 7.3 10.1 17 5.3 0.5 4.3 4 2 1 5 5 5 0 Aureocin-like type II bacteriocin ART PF01129.18 EKX50093.1 - 1.5e-08 34.2 0.0 1.9e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 NAD:arginine ADP-ribosyltransferase ADPrib_exo_Tox PF03496.14 EKX50093.1 - 3.4e-07 29.8 0.0 3e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosyltransferase exoenzyme Ion_trans PF00520.31 EKX50094.1 - 2e-34 119.0 18.7 3e-34 118.4 18.7 1.2 1 0 0 1 1 1 1 Ion transport protein EF-hand_1 PF00036.32 EKX50094.1 - 1.6e-14 52.3 4.4 4e-05 22.9 0.3 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EKX50094.1 - 9.7e-14 50.1 0.3 0.0057 16.5 0.1 4.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 EKX50094.1 - 5.6e-12 45.9 1.1 3.3e-07 30.7 0.1 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX50094.1 - 3.9e-10 38.7 5.7 7.4e-06 25.2 0.3 3.8 3 0 0 3 3 3 3 EF hand PKD_channel PF08016.12 EKX50094.1 - 6.5e-08 31.7 14.2 3e-05 22.9 5.9 2.2 1 1 1 2 2 2 2 Polycystin cation channel EF-hand_8 PF13833.6 EKX50094.1 - 1.9e-06 27.6 3.3 0.00096 19.0 0.0 4.1 4 1 1 5 5 5 2 EF-hand domain pair PH PF00169.29 EKX50094.1 - 3.4e-05 24.3 0.0 6.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 PH domain FliS PF02561.14 EKX50094.1 - 0.00067 19.9 0.6 0.0033 17.7 0.1 2.4 2 0 0 2 2 2 1 Flagellar protein FliS EF-hand_4 PF12763.7 EKX50094.1 - 0.043 13.8 0.1 0.44 10.5 0.0 2.6 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand HECT_2 PF09814.9 EKX50094.1 - 0.074 11.9 1.2 0.075 11.9 0.0 1.5 2 0 0 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding TPR_2 PF07719.17 EKX50095.1 - 0.0091 16.0 0.7 0.085 13.0 0.5 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat SNAP PF14938.6 EKX50095.1 - 0.01 15.3 0.2 0.014 14.9 0.2 1.3 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_8 PF13181.6 EKX50095.1 - 0.039 14.2 0.9 0.097 12.9 0.4 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat SH3_1 PF00018.28 EKX50095.1 - 0.067 12.8 0.0 0.19 11.4 0.0 1.9 1 0 0 1 1 1 0 SH3 domain DUF1699 PF08004.11 EKX50095.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1699) TPR_2 PF07719.17 EKX50096.1 - 0.0026 17.7 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX50096.1 - 0.0031 17.8 0.1 0.0036 17.6 0.1 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX50096.1 - 0.05 13.6 0.3 0.15 12.2 0.0 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat NICE-1 PF15845.5 EKX50097.1 - 0.67 10.8 10.6 0.042 14.6 3.5 2.2 1 1 1 2 2 2 0 Cysteine-rich C-terminal 1 family Sushi PF00084.20 EKX50098.1 - 1.9e-24 86.0 111.4 0.19 12.4 0.0 27.7 27 0 0 27 27 27 13 Sushi repeat (SCR repeat) DUF1372 PF07116.11 EKX50098.1 - 0.032 14.4 0.0 15 5.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1372) Thyroglobulin_1 PF00086.18 EKX50098.1 - 1.5 8.5 13.2 3.2 7.5 1.1 3.7 3 0 0 3 3 3 0 Thyroglobulin type-1 repeat ArfA PF03889.13 EKX50099.1 - 0.19 11.3 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Alternative ribosome-rescue factor A DTW PF03942.15 EKX50100.1 - 1.1e-22 80.7 9.4 8.8e-22 77.8 0.4 2.5 1 1 1 2 2 2 2 DTW domain Pneumo_M2 PF07380.11 EKX50100.1 - 0.058 13.7 0.3 0.47 10.7 0.0 2.5 3 0 0 3 3 3 0 Pneumovirus M2 protein DUF1985 PF09331.11 EKX50100.1 - 0.14 12.1 1.9 0.25 11.3 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1985) Ank_2 PF12796.7 EKX50101.1 - 2.3e-08 34.5 0.1 8.7e-08 32.7 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) AAA_2 PF07724.14 EKX50101.1 - 1.1e-07 32.1 0.0 5.6e-07 29.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 EKX50101.1 - 3e-07 30.9 0.0 7.2e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Ank_5 PF13857.6 EKX50101.1 - 5.8e-07 29.7 0.2 2.5e-06 27.6 0.2 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX50101.1 - 1.5e-06 28.6 0.0 2.8e-05 24.6 0.1 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX50101.1 - 1.6e-06 28.3 0.1 0.0052 17.2 0.0 3.1 3 0 0 3 3 2 2 Ankyrin repeat AAA_5 PF07728.14 EKX50101.1 - 1.8e-06 28.0 0.0 3.4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Ank_3 PF13606.6 EKX50101.1 - 2.9e-05 24.1 0.0 0.094 13.3 0.0 3.2 3 0 0 3 3 2 2 Ankyrin repeat Torsin PF06309.11 EKX50101.1 - 0.00019 21.5 0.0 0.00049 20.2 0.0 1.6 1 0 0 1 1 1 1 Torsin AAA_14 PF13173.6 EKX50101.1 - 0.00028 20.9 0.0 0.00073 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EKX50101.1 - 0.00059 20.1 0.0 0.0017 18.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EKX50101.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.6 EKX50101.1 - 0.038 14.4 0.0 0.16 12.3 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 EKX50101.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EKX50101.1 - 0.066 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.21 EKX50101.1 - 0.11 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EKX50101.1 - 0.17 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Rubis-subs-bind PF09273.11 EKX50103.1 - 1.1e-08 35.8 0.4 2.8e-08 34.5 0.4 1.8 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding LemA PF04011.12 EKX50103.1 - 0.076 12.9 0.2 0.47 10.3 0.1 2.1 2 0 0 2 2 2 0 LemA family DUF2677 PF10838.8 EKX50103.1 - 0.15 12.0 0.0 27 4.7 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2677) Med18 PF09637.10 EKX50104.1 - 0.076 12.8 0.0 2.1 8.1 0.0 2.1 2 0 0 2 2 2 0 Med18 protein PRIMA1 PF16101.5 EKX50104.1 - 0.63 10.1 11.4 0.21 11.6 5.8 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 SMN PF06003.12 EKX50104.1 - 0.65 9.2 3.2 0.91 8.7 3.2 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) SNF2_N PF00176.23 EKX50105.1 - 6.7e-56 189.5 0.1 2e-55 187.9 0.1 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX50105.1 - 7.2e-20 71.4 0.0 3e-19 69.4 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 EKX50105.1 - 7.3e-20 70.6 6.1 1.6e-12 47.2 1.4 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 EKX50105.1 - 9.6e-11 42.0 0.0 3.5e-10 40.1 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Agenet PF05641.12 EKX50105.1 - 2.4e-08 34.3 2.0 0.0055 17.1 0.4 2.9 2 0 0 2 2 2 2 Agenet domain Tudor_4 PF18358.1 EKX50105.1 - 3.3e-07 29.8 8.4 0.00011 21.7 0.5 3.3 2 1 1 3 3 3 2 Histone methyltransferase Tudor domain DUF2075 PF09848.9 EKX50105.1 - 0.00046 19.6 0.0 0.0032 16.8 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 EKX50105.1 - 0.00054 19.8 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase MBT PF02820.18 EKX50105.1 - 0.021 15.1 0.4 2.4 8.6 0.0 2.6 2 0 0 2 2 2 0 mbt repeat DUF4167 PF13763.6 EKX50105.1 - 0.12 12.6 0.0 0.43 10.8 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4167) RRM_1 PF00076.22 EKX50106.1 - 4.4e-11 42.4 0.1 5.5e-11 42.1 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) V_ATPase_I PF01496.19 EKX50107.1 - 4.6e-268 891.5 4.1 5.5e-184 613.4 0.1 2.3 2 1 0 2 2 2 2 V-type ATPase 116kDa subunit family DivIC PF04977.15 EKX50107.1 - 0.066 13.0 1.9 0.57 10.0 0.0 2.6 2 0 0 2 2 2 0 Septum formation initiator Mod_r PF07200.13 EKX50107.1 - 0.18 11.9 5.3 0.13 12.4 1.3 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Cep57_MT_bd PF06657.13 EKX50107.1 - 0.44 11.0 4.2 0.74 10.3 1.3 2.3 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Seryl_tRNA_N PF02403.22 EKX50107.1 - 7.6 6.8 6.1 1.4 9.2 0.2 2.4 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TPR_17 PF13431.6 EKX50108.1 - 3.5e-42 139.8 31.9 0.002 18.3 0.0 17.9 19 0 0 19 19 19 9 Tetratricopeptide repeat TPR_14 PF13428.6 EKX50108.1 - 7.2e-28 94.9 48.3 0.00083 20.0 0.1 16.6 5 4 13 18 18 18 8 Tetratricopeptide repeat TPR_1 PF00515.28 EKX50108.1 - 1.3e-20 72.3 41.9 0.021 14.6 0.1 15.6 18 0 0 18 18 18 6 Tetratricopeptide repeat TPR_8 PF13181.6 EKX50108.1 - 2.9e-20 70.7 41.4 0.083 13.1 0.1 15.9 18 0 0 18 18 17 7 Tetratricopeptide repeat TPR_2 PF07719.17 EKX50108.1 - 7.9e-19 66.2 47.8 0.021 14.9 0.1 15.9 20 0 0 20 20 18 6 Tetratricopeptide repeat TPR_16 PF13432.6 EKX50108.1 - 1.6e-12 47.9 46.3 0.00022 21.8 0.3 11.0 6 4 4 12 12 12 6 Tetratricopeptide repeat TPR_19 PF14559.6 EKX50108.1 - 1.8e-12 47.6 50.1 0.0087 16.6 2.1 12.6 11 5 3 14 14 12 6 Tetratricopeptide repeat TPR_7 PF13176.6 EKX50108.1 - 1.2e-10 40.7 38.2 0.098 12.7 0.0 13.8 16 0 0 16 16 14 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX50108.1 - 5.4e-10 39.4 51.7 0.0048 17.1 0.4 12.1 7 4 6 13 13 12 3 Tetratricopeptide repeat Sel1 PF08238.12 EKX50108.1 - 6.9e-06 26.6 29.3 14 6.5 0.0 12.0 13 0 0 13 13 12 0 Sel1 repeat Suf PF05843.14 EKX50108.1 - 3.5e-05 23.9 1.5 0.012 15.6 0.1 3.6 4 1 1 5 5 3 1 Suppressor of forked protein (Suf) TPR_15 PF13429.6 EKX50108.1 - 4.7e-05 22.7 24.2 0.049 12.8 0.7 7.0 2 2 2 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX50108.1 - 0.00076 19.1 28.3 4.7 7.0 0.0 11.2 14 1 1 15 15 13 2 TPR repeat Coatomer_E PF04733.14 EKX50108.1 - 0.0026 17.2 2.5 0.66 9.3 0.0 4.8 5 1 0 5 5 5 1 Coatomer epsilon subunit TPR_6 PF13174.6 EKX50108.1 - 0.0031 18.0 24.4 2.1 9.2 0.0 9.6 13 0 0 13 13 7 1 Tetratricopeptide repeat DUF2989 PF11207.8 EKX50108.1 - 0.0044 16.8 6.0 0.28 10.9 0.4 4.7 4 2 2 6 6 6 1 Protein of unknown function (DUF2989) Phage_GPL PF05926.11 EKX50108.1 - 0.016 15.2 1.6 0.27 11.2 0.1 3.3 3 0 0 3 3 3 0 Phage head completion protein (GPL) DUF2274 PF10038.9 EKX50108.1 - 0.03 14.8 9.1 35 4.9 0.0 6.0 6 1 1 7 7 6 0 Protein of unknown function (DUF2274) TPR_9 PF13371.6 EKX50108.1 - 0.11 12.6 13.2 7.9 6.7 0.3 5.9 6 1 0 6 6 5 0 Tetratricopeptide repeat 14-3-3 PF00244.20 EKX50108.1 - 0.15 11.5 1.7 2.8 7.4 0.0 3.9 4 1 1 5 5 5 0 14-3-3 protein ComR_TPR PF18710.1 EKX50108.1 - 0.49 9.9 0.0 0.49 9.9 0.0 5.1 7 1 1 8 8 8 0 ComR tetratricopeptide DUF4167 PF13763.6 EKX50108.1 - 1 9.6 4.2 19 5.5 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4167) DJ-1_PfpI PF01965.24 EKX50110.1 - 1.3e-107 356.9 0.1 8.9e-53 178.5 0.0 2.0 2 0 0 2 2 2 2 DJ-1/PfpI family GATase PF00117.28 EKX50110.1 - 1.9e-09 37.6 0.0 0.0001 22.1 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferase class-I ThiJ_like PF17124.5 EKX50110.1 - 4e-08 33.2 0.1 0.0077 15.9 0.0 3.3 2 2 0 3 3 3 2 ThiJ/PfpI family-like GATase_3 PF07685.14 EKX50110.1 - 8.4e-06 25.5 0.1 0.067 12.8 0.0 2.6 3 0 0 3 3 3 2 CobB/CobQ-like glutamine amidotransferase domain GATase_5 PF13507.6 EKX50110.1 - 0.0022 17.1 0.0 0.48 9.5 0.0 2.6 2 1 0 2 2 2 2 CobB/CobQ-like glutamine amidotransferase domain Catalase_C PF18011.1 EKX50110.1 - 0.0024 17.5 0.0 0.12 12.0 0.0 2.3 2 0 0 2 2 2 1 C-terminal domain found in long catalases Peptidase_C26 PF07722.13 EKX50110.1 - 0.0046 16.7 0.1 0.23 11.2 0.0 2.9 2 2 0 2 2 2 1 Peptidase C26 SNO PF01174.19 EKX50110.1 - 0.017 14.9 0.0 2.5 7.9 0.0 2.2 2 0 0 2 2 2 0 SNO glutamine amidotransferase family HTS PF04204.16 EKX50110.1 - 0.02 13.8 0.0 2.3 7.1 0.0 2.1 2 0 0 2 2 2 0 Homoserine O-succinyltransferase Putative_PNPOx PF01243.20 EKX50111.1 - 3e-11 43.3 0.0 4.7e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 EKX50111.1 - 2.3e-05 24.4 0.0 3.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 EKX50111.1 - 0.0065 16.1 0.0 0.011 15.3 0.0 1.4 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like CD34_antigen PF06365.12 EKX50111.1 - 0.047 13.3 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family NCE101 PF11654.8 EKX50111.1 - 0.28 10.9 1.2 3 7.6 1.2 2.2 1 1 0 1 1 1 0 Non-classical export protein 1 cobW PF02492.19 EKX50112.1 - 2e-58 196.9 1.2 2.7e-58 196.4 1.2 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EKX50112.1 - 5e-18 64.8 0.1 8.2e-18 64.1 0.1 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 EKX50112.1 - 0.00042 20.3 0.6 0.64 9.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase ATPase_2 PF01637.18 EKX50112.1 - 0.0063 16.4 0.1 0.014 15.3 0.1 1.6 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 EKX50112.1 - 0.024 14.4 0.0 0.097 12.4 0.0 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase GTP_EFTU PF00009.27 EKX50112.1 - 0.038 13.5 5.1 0.36 10.3 5.0 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 EKX50112.1 - 0.045 14.3 0.7 0.35 11.4 0.3 2.4 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EKX50112.1 - 0.05 14.0 0.0 0.14 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 EKX50112.1 - 0.052 12.6 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 EKX50112.1 - 0.067 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain MobB PF03205.14 EKX50112.1 - 0.089 12.7 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 EKX50112.1 - 0.089 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EKX50112.1 - 0.11 12.6 0.1 0.26 11.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EKX50112.1 - 0.13 12.4 1.1 1.1 9.3 1.1 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 EKX50112.1 - 0.13 12.8 0.1 0.3 11.6 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 EKX50112.1 - 0.15 12.3 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EKX50112.1 - 0.64 10.5 3.0 1 9.8 0.2 2.1 2 0 0 2 2 2 0 AAA domain CobD_Cbib PF03186.13 EKX50113.1 - 2.6e-75 253.2 0.1 4.7e-75 252.4 0.1 1.3 1 0 0 1 1 1 1 CobD/Cbib protein CbiZ PF01955.18 EKX50113.1 - 3.5e-44 151.2 0.1 5.3e-44 150.6 0.1 1.3 1 0 0 1 1 1 1 Adenosylcobinamide amidohydrolase Amidase PF01425.21 EKX50114.1 - 4.2e-64 217.2 0.2 5e-64 216.9 0.2 1.1 1 0 0 1 1 1 1 Amidase LRR_6 PF13516.6 EKX50115.1 - 4.2e-12 45.1 14.5 0.077 13.1 0.0 7.9 8 0 0 8 8 8 5 Leucine Rich repeat EF-hand_1 PF00036.32 EKX50115.1 - 8.3e-10 37.5 1.3 4.6e-05 22.7 0.2 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX50115.1 - 3.6e-09 35.8 1.1 0.00068 19.4 0.2 3.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EKX50115.1 - 6.7e-09 34.9 3.7 0.00033 20.0 0.7 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX50115.1 - 1.2e-07 32.0 1.3 1e-06 29.1 0.7 3.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 EKX50115.1 - 3.2e-05 23.7 0.2 0.025 14.4 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain pair LRR_4 PF12799.7 EKX50115.1 - 8e-05 22.9 5.2 0.18 12.3 1.5 5.3 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX50115.1 - 0.0017 18.1 5.6 0.97 9.2 0.1 4.5 3 1 1 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 EKX50115.1 - 0.0096 16.3 3.8 17 6.4 0.0 5.7 5 0 0 5 5 5 0 Leucine Rich Repeat CNDH2_C PF16858.5 EKX50115.1 - 0.42 10.4 5.6 0.82 9.5 5.6 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DNA_pol_phi PF04931.13 EKX50115.1 - 3.5 5.6 9.0 5.9 4.9 9.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi PET117 PF15786.5 EKX50116.1 - 3.7 7.9 8.4 1.2 9.5 4.9 2.0 2 0 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial 14-3-3 PF00244.20 EKX50117.1 - 7.2e-105 349.4 4.9 8.2e-105 349.2 4.9 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_19 PF14559.6 EKX50117.1 - 0.011 16.2 4.0 0.59 10.7 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat XhlA PF10779.9 EKX50117.1 - 2.4 8.4 5.6 0.91 9.8 2.3 1.9 2 0 0 2 2 2 0 Haemolysin XhlA PDZ PF00595.24 EKX50118.1 - 5.2e-17 62.0 1.6 1.5e-10 41.2 0.2 2.7 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EKX50118.1 - 2.3e-12 46.5 2.9 2.4e-07 30.5 0.4 3.2 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 EKX50118.1 - 6.2e-08 32.9 0.3 5.4e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 PDZ domain Cupin_8 PF13621.6 EKX50118.1 - 2.7e-05 24.0 10.8 3.5e-05 23.7 0.1 3.3 2 1 0 2 2 2 1 Cupin-like domain Tricorn_PDZ PF14685.6 EKX50118.1 - 0.0012 18.7 0.1 1.1 9.3 0.0 2.9 2 0 0 2 2 2 2 Tricorn protease PDZ domain PDZ_4 PF17816.1 EKX50118.1 - 0.0088 16.4 0.1 0.1 13.0 0.0 2.7 2 0 0 2 2 2 1 PDZ domain F-box PF00646.33 EKX50118.1 - 0.29 11.1 1.5 0.42 10.6 0.3 1.9 2 0 0 2 2 2 0 F-box domain Usp PF00582.26 EKX50120.1 - 4.2e-27 95.4 0.7 5.8e-20 72.2 0.1 2.5 2 1 0 2 2 2 2 Universal stress protein family Melibiase PF02065.18 EKX50121.1 - 4.3e-14 52.2 0.0 6.3e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Melibiase Glyco_hydro_31 PF01055.26 EKX50121.1 - 0.00079 18.7 0.1 0.001 18.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 PKD_channel PF08016.12 EKX50122.1 - 1.9e-25 89.5 21.0 1.5e-12 47.0 16.6 2.2 1 1 1 2 2 2 2 Polycystin cation channel WW PF00397.26 EKX50122.1 - 1.2e-08 34.9 2.2 2.7e-08 33.7 2.2 1.7 1 0 0 1 1 1 1 WW domain Glyco_transf_49 PF13896.6 EKX50124.1 - 7.1e-33 114.3 0.0 1.6e-32 113.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glyco_transf_18 PF15024.6 EKX50124.1 - 3.2e-08 32.7 2.7 4.3e-08 32.2 2.7 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 18 Glycos_transf_2 PF00535.26 EKX50124.1 - 0.024 14.5 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 ABC_tran PF00005.27 EKX50126.1 - 4.1e-39 134.2 0.0 8.9e-20 71.6 0.0 3.5 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EKX50126.1 - 7.3e-12 45.7 4.0 0.0012 18.8 0.0 4.2 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EKX50126.1 - 1.3e-11 44.4 0.4 0.00046 19.7 0.0 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EKX50126.1 - 3.3e-07 30.3 0.0 0.011 15.7 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EKX50126.1 - 1.3e-06 28.4 0.1 0.016 15.3 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase NACHT PF05729.12 EKX50126.1 - 2.7e-06 27.4 0.0 0.12 12.3 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.6 EKX50126.1 - 3.9e-06 27.5 0.1 0.056 14.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 EKX50126.1 - 1.1e-05 25.9 0.4 0.066 13.6 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain Roc PF08477.13 EKX50126.1 - 2.3e-05 24.6 0.0 0.027 14.7 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 EKX50126.1 - 4.5e-05 23.7 0.1 0.043 14.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 EKX50126.1 - 0.00018 21.2 0.3 0.37 10.4 0.0 2.6 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EKX50126.1 - 0.00022 20.3 0.1 0.46 9.4 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 EKX50126.1 - 0.00026 21.6 0.1 0.69 10.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EKX50126.1 - 0.00027 21.2 0.4 0.87 9.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.6 EKX50126.1 - 0.00046 20.4 0.1 1.7 8.9 0.0 3.1 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 EKX50126.1 - 0.00047 19.4 0.3 0.14 11.3 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.6 EKX50126.1 - 0.0006 19.6 0.2 1.5 8.5 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.6 EKX50126.1 - 0.001 18.8 0.0 2.1 8.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SRP54 PF00448.22 EKX50126.1 - 0.0011 18.6 0.0 0.92 9.1 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MobB PF03205.14 EKX50126.1 - 0.0011 18.8 0.1 1.3 8.9 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.6 EKX50126.1 - 0.0015 18.2 0.0 2.9 7.4 0.0 3.0 3 1 0 3 3 3 2 AAA domain AAA PF00004.29 EKX50126.1 - 0.0015 19.0 0.0 2.1 8.8 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EKX50126.1 - 0.0019 18.3 0.1 0.43 10.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain DUF3584 PF12128.8 EKX50126.1 - 0.002 15.8 4.4 0.0069 14.0 0.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) Arf PF00025.21 EKX50126.1 - 0.0021 17.5 0.1 0.66 9.4 0.1 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_30 PF13604.6 EKX50126.1 - 0.0027 17.4 0.0 2.1 8.0 0.0 3.3 4 0 0 4 4 3 1 AAA domain FeoB_N PF02421.18 EKX50126.1 - 0.0041 16.7 0.3 0.049 13.2 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_33 PF13671.6 EKX50126.1 - 0.0054 16.9 0.0 3.3 7.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 EKX50126.1 - 0.0074 16.1 0.1 0.025 14.4 0.0 1.8 2 0 0 2 2 2 1 Bacterial dnaA protein NTPase_1 PF03266.15 EKX50126.1 - 0.011 15.6 0.2 1.4 8.8 0.0 3.3 4 0 0 4 4 4 0 NTPase DUF87 PF01935.17 EKX50126.1 - 0.015 15.4 0.3 2.2 8.3 0.3 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain PduV-EutP PF10662.9 EKX50126.1 - 0.027 14.2 0.2 11 5.7 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 EKX50126.1 - 0.03 13.6 0.1 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Septin Dynamin_N PF00350.23 EKX50126.1 - 0.033 14.3 0.0 2.1 8.4 0.0 2.4 2 0 0 2 2 2 0 Dynamin family DLIC PF05783.11 EKX50126.1 - 0.043 12.6 0.2 4.5 6.0 0.1 2.2 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_17 PF13207.6 EKX50126.1 - 0.072 13.5 0.0 19 5.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 EKX50126.1 - 0.073 12.3 0.0 0.49 9.6 0.0 1.9 1 1 0 2 2 2 0 KAP family P-loop domain ATPase_2 PF01637.18 EKX50126.1 - 0.073 13.0 0.0 0.55 10.1 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_13 PF13166.6 EKX50126.1 - 0.075 11.7 0.0 4.5 5.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EKX50126.1 - 0.085 12.8 0.0 4.9 7.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 EKX50126.1 - 0.088 12.8 0.2 6.1 6.9 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 EKX50126.1 - 0.092 12.5 0.0 14 5.4 0.0 3.0 2 1 1 3 3 3 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 EKX50126.1 - 0.13 12.7 0.0 3.9 7.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_15 PF13175.6 EKX50126.1 - 0.17 11.6 0.1 15 5.1 0.0 3.1 4 0 0 4 4 4 0 AAA ATPase domain Metallophos PF00149.28 EKX50127.1 - 1.2e-09 39.0 0.1 2e-09 38.3 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase HEAT PF02985.22 EKX50128.1 - 1.2e-18 65.6 21.4 0.01 16.0 0.0 10.8 11 0 0 11 11 11 6 HEAT repeat HEAT_2 PF13646.6 EKX50128.1 - 2.2e-10 40.8 8.0 0.0046 17.3 0.0 7.1 7 1 0 7 7 7 2 HEAT repeats HEAT_EZ PF13513.6 EKX50128.1 - 9e-09 35.7 17.5 0.073 13.6 0.0 9.6 11 0 0 11 11 11 2 HEAT-like repeat Cnd1 PF12717.7 EKX50128.1 - 4.6e-08 33.3 14.7 0.015 15.4 0.2 7.2 6 2 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 DUF4042 PF13251.6 EKX50128.1 - 5.5e-05 22.9 0.5 4 7.1 0.0 5.4 5 0 0 5 5 5 1 Domain of unknown function (DUF4042) CLASP_N PF12348.8 EKX50128.1 - 0.00043 19.9 8.5 0.061 12.9 0.1 5.3 5 1 0 5 5 5 2 CLASP N terminal TIP120 PF08623.10 EKX50128.1 - 0.003 17.4 0.1 0.12 12.2 0.0 3.6 5 1 1 6 6 6 1 TATA-binding protein interacting (TIP20) RasGEF_N_2 PF14663.6 EKX50128.1 - 0.014 15.8 1.0 6.3 7.2 0.0 4.5 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain CAS_CSE1 PF03378.15 EKX50128.1 - 0.03 12.8 0.0 1.2 7.6 0.0 2.5 2 0 0 2 2 2 0 CAS/CSE protein, C-terminus CaiF_GrlA PF07180.11 EKX50129.1 - 0.011 15.7 0.0 0.053 13.5 0.0 2.2 2 0 0 2 2 2 0 CaiF/GrlA transcriptional regulator DUF2613 PF11021.8 EKX50130.1 - 0.0045 17.1 0.3 0.098 12.8 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2613) AAA_12 PF13087.6 EKX50131.1 - 8.7e-23 81.0 0.1 1.1e-22 80.6 0.1 1.1 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EKX50131.1 - 3.2e-08 33.3 0.0 7.1e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EKX50131.1 - 1.7e-05 24.7 0.0 1.9e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase UvrD_C PF13361.6 EKX50131.1 - 0.00051 19.5 0.0 0.0011 18.4 0.0 1.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_12 PF13087.6 EKX50132.1 - 1.7e-42 145.3 0.0 2.2e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF2594 PF10769.9 EKX50132.1 - 0.033 14.2 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2594) DUF2075 PF09848.9 EKX50132.1 - 0.093 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ephrin_rec_like PF07699.13 EKX50133.1 - 7.6e-32 108.8 76.6 1.6e-08 34.2 2.2 7.3 4 3 3 7 7 7 7 Putative ephrin-receptor like NCD3G PF07562.14 EKX50133.1 - 2e-06 27.7 59.9 0.012 15.6 6.3 7.4 1 1 6 8 8 8 7 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX50133.1 - 0.025 15.0 59.9 0.15 12.5 2.2 8.6 2 2 6 8 8 8 0 TNFR/NGFR cysteine-rich region MscS_porin PF12795.7 EKX50135.1 - 0.0021 17.6 11.1 0.0021 17.6 11.1 3.9 3 2 0 4 4 4 1 Mechanosensitive ion channel porin domain DUF4407 PF14362.6 EKX50135.1 - 8.4 5.6 36.8 1.8 7.8 8.9 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Methyltransf_21 PF05050.12 EKX50136.1 - 1.1e-15 58.0 0.1 3e-15 56.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase FkbM domain Glyco_transf_41 PF13844.6 EKX50137.1 - 2.4e-38 131.8 0.2 2.4e-21 75.7 0.0 2.3 1 1 1 2 2 2 2 Glycosyl transferase family 41 Med3 PF11593.8 EKX50137.1 - 0.00085 18.6 2.5 0.0012 18.1 2.5 1.1 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal DUF2722 PF10846.8 EKX50137.1 - 0.21 10.5 6.0 0.35 9.8 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) OrfB_IS605 PF01385.19 EKX50137.1 - 0.58 10.4 3.1 1.7 8.9 3.1 1.7 1 0 0 1 1 1 0 Probable transposase Spt20 PF12090.8 EKX50137.1 - 1.2 8.7 12.4 2.4 7.7 12.4 1.4 1 0 0 1 1 1 0 Spt20 family Zn_clus PF00172.18 EKX50139.1 - 6.2e-07 29.4 11.8 1e-06 28.7 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UDG PF03167.19 EKX50140.1 - 8.2e-23 81.1 0.0 1.1e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily WD40 PF00400.32 EKX50141.1 - 8e-33 112.0 20.9 4.5e-08 33.6 0.0 7.5 6 1 0 6 6 6 4 WD domain, G-beta repeat PUB PF09409.10 EKX50141.1 - 2.8e-12 46.4 0.2 6.7e-12 45.2 0.1 1.7 2 0 0 2 2 2 1 PUB domain BBS2_Mid PF14783.6 EKX50141.1 - 3.8e-05 23.7 0.0 0.0044 17.0 0.0 2.7 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region ANAPC4_WD40 PF12894.7 EKX50141.1 - 0.031 14.6 0.4 19 5.6 0.0 3.8 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Bacillus_HBL PF05791.11 EKX50141.1 - 0.068 13.0 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) PFU PF09070.11 EKX50142.1 - 2.6e-07 30.9 0.6 4e-07 30.3 0.6 1.2 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) Pex24p PF06398.11 EKX50142.1 - 4.1e-05 22.8 2.0 0.076 12.0 2.0 2.4 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin PNISR PF15996.5 EKX50142.1 - 0.046 14.0 11.1 0.059 13.6 11.1 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR NPR3 PF03666.13 EKX50142.1 - 0.1 11.4 9.2 0.13 11.1 9.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF913 PF06025.12 EKX50142.1 - 0.79 8.6 5.5 1.1 8.2 5.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Nop14 PF04147.12 EKX50142.1 - 1.3 7.1 51.2 1.6 6.9 51.2 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EKX50142.1 - 3.8 6.8 51.3 4.7 6.5 51.3 1.0 1 0 0 1 1 1 0 SDA1 RNA_pol_Rpc4 PF05132.14 EKX50142.1 - 3.8 7.9 5.2 5.9 7.3 5.2 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Mpp10 PF04006.12 EKX50142.1 - 9.7 4.5 38.5 13 4.1 38.5 1.1 1 0 0 1 1 1 0 Mpp10 protein PUL PF08324.11 EKX50143.1 - 6.3e-09 35.5 1.6 8.3e-09 35.1 1.6 1.1 1 0 0 1 1 1 1 PUL domain YbaJ PF10757.9 EKX50143.1 - 0.16 12.6 0.0 0.25 11.9 0.0 1.3 1 0 0 1 1 1 0 Biofilm formation regulator YbaJ RRM_1 PF00076.22 EKX50144.1 - 3.3e-36 122.9 0.8 1.6e-18 66.2 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EKX50144.1 - 2.8e-12 46.6 2.1 2.7e-06 27.4 0.4 2.6 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 EKX50144.1 - 2.8e-05 23.7 0.0 4.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EKX50144.1 - 0.0025 17.8 0.2 2.4 8.2 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EKX50144.1 - 0.02 14.9 0.4 2 8.5 0.1 2.3 2 0 0 2 2 2 0 RNA binding motif RL PF17797.1 EKX50144.1 - 0.12 12.3 0.1 0.45 10.5 0.1 1.9 2 1 0 2 2 2 0 RL domain Mito_carr PF00153.27 EKX50145.1 - 3.5e-59 196.7 2.3 2.9e-21 75.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Rad60-SLD_2 PF13881.6 EKX50146.1 - 1.9e-18 66.5 0.0 2.1e-18 66.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EKX50146.1 - 5.1e-08 32.6 0.0 9.7e-08 31.7 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EKX50146.1 - 0.0065 16.3 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EKX50146.1 - 0.012 15.9 0.0 0.019 15.3 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 EKX50146.1 - 0.019 15.5 0.0 0.02 15.5 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Glyco_transf_41 PF13844.6 EKX50147.1 - 6e-28 97.5 0.1 4e-17 61.8 0.0 2.6 1 1 2 3 3 3 2 Glycosyl transferase family 41 TPR_16 PF13432.6 EKX50147.1 - 1.6e-05 25.4 0.0 0.06 14.0 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX50147.1 - 5.2e-05 23.1 3.0 0.028 14.6 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX50147.1 - 0.0032 17.4 0.1 1.2 9.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX50147.1 - 0.006 16.7 0.1 0.14 12.3 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX50147.1 - 0.0096 15.7 0.0 0.68 9.8 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX50147.1 - 0.059 13.9 0.2 3.7 8.1 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX50147.1 - 0.071 14.0 0.7 1.8 9.6 0.1 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX50147.1 - 0.11 12.8 0.1 2.1 8.7 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX50147.1 - 0.16 12.2 0.3 0.71 10.1 0.0 2.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Atx10homo_assoc PF09759.9 EKX50148.1 - 0.0037 17.3 1.9 0.048 13.7 0.3 3.8 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 EKX50148.1 - 0.037 14.1 15.9 6.8 6.9 0.0 7.6 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EKX50148.1 - 0.16 12.3 4.3 0.57 10.6 0.8 3.7 4 1 0 4 4 4 0 HEAT repeats DUF2428 PF10350.9 EKX50149.1 - 2e-37 129.0 0.4 1e-24 87.3 0.4 3.4 2 1 1 3 3 3 2 Putative death-receptor fusion protein (DUF2428) DUF577 PF04510.12 EKX50149.1 - 0.025 14.5 0.1 0.35 10.8 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF577) CK2S PF15011.6 EKX50150.1 - 1.1e-13 51.4 0.4 1.4e-13 51.0 0.4 1.1 1 0 0 1 1 1 1 Casein Kinase 2 substrate LSM PF01423.22 EKX50151.1 - 4.4e-22 77.5 0.6 4.9e-22 77.4 0.6 1.0 1 0 0 1 1 1 1 LSM domain Polysacc_deac_1 PF01522.21 EKX50152.1 - 0.042 13.8 0.8 0.11 12.4 0.2 2.0 2 0 0 2 2 2 0 Polysaccharide deacetylase ZapB PF06005.12 EKX50152.1 - 0.33 11.4 10.3 0.096 13.1 4.0 3.1 3 0 0 3 3 3 0 Cell division protein ZapB DivIC PF04977.15 EKX50152.1 - 0.48 10.2 12.1 0.44 10.3 2.1 3.4 3 0 0 3 3 3 0 Septum formation initiator DUF4407 PF14362.6 EKX50152.1 - 9.2 5.5 20.7 18 4.5 18.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) CBS PF00571.28 EKX50153.1 - 1.5e-24 86.2 0.6 2.2e-07 31.2 0.0 4.1 4 1 0 4 4 4 3 CBS domain AMP-binding PF00501.28 EKX50154.1 - 5.7e-40 137.2 0.0 6.8e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF5626 PF18540.1 EKX50154.1 - 0.15 12.6 0.1 0.56 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5626) Golgin_A5 PF09787.9 EKX50155.1 - 0.0013 18.3 21.9 0.0013 18.3 21.9 3.7 1 1 3 4 4 4 3 Golgin subfamily A member 5 ZapB PF06005.12 EKX50155.1 - 0.0026 18.1 4.5 0.0026 18.1 4.5 6.8 2 2 4 6 6 6 1 Cell division protein ZapB bZIP_1 PF00170.21 EKX50155.1 - 0.0069 16.5 3.3 0.0069 16.5 3.3 5.6 4 2 1 5 5 5 2 bZIP transcription factor PRKG1_interact PF15898.5 EKX50155.1 - 0.0075 17.1 10.2 0.0075 17.1 10.2 6.4 1 1 3 4 4 4 1 cGMP-dependent protein kinase interacting domain LPP PF04728.13 EKX50155.1 - 0.29 11.5 13.9 0.57 10.6 0.5 4.4 4 0 0 4 4 4 0 Lipoprotein leucine-zipper XS PF03468.14 EKX50155.1 - 0.76 10.1 3.0 1.7 9.0 0.3 2.8 2 1 1 3 3 3 0 XS domain Spc7 PF08317.11 EKX50155.1 - 1.6 7.5 58.6 0.049 12.5 21.0 3.5 2 2 1 3 3 3 0 Spc7 kinetochore protein Pre-PUA PF17832.1 EKX50156.1 - 0.71 10.6 3.5 5.3 7.8 0.3 3.0 2 0 0 2 2 2 0 Pre-PUA-like domain DUF2730 PF10805.8 EKX50156.1 - 1 9.5 15.0 4.3 7.5 1.7 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF2730) Tup_N PF08581.10 EKX50157.1 - 0.03 14.6 12.5 0.048 14.0 0.8 3.6 3 0 0 3 3 3 0 Tup N-terminal Gp-FAR-1 PF05823.12 EKX50157.1 - 0.064 13.6 2.0 0.075 13.4 0.6 1.8 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) TPR_MLP1_2 PF07926.12 EKX50157.1 - 0.71 9.9 11.5 3.5 7.7 2.9 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HAUS6_N PF14661.6 EKX50157.1 - 1.1 8.7 6.5 2.7 7.5 2.4 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF4600 PF15372.6 EKX50157.1 - 2.9 8.4 12.5 8.7 6.8 10.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) HALZ PF02183.18 EKX50157.1 - 4.3 7.6 9.2 0.31 11.3 1.8 2.9 3 1 0 3 3 3 0 Homeobox associated leucine zipper TEX13 PF15186.6 EKX50157.1 - 4.7 6.9 11.4 1.5 8.5 1.2 2.5 2 1 1 3 3 3 0 Testis-expressed sequence 13 protein family DUF1664 PF07889.12 EKX50157.1 - 5.7 7.0 11.5 13 5.9 7.5 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) FapA PF03961.13 EKX50158.1 - 0.046 12.3 8.2 0.0075 14.9 4.2 1.6 2 0 0 2 2 2 0 Flagellar Assembly Protein A COG5 PF10392.9 EKX50158.1 - 0.05 13.8 1.8 0.13 12.4 1.8 1.7 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Trimer_CC PF08954.11 EKX50158.1 - 0.25 10.9 1.4 0.45 10.1 0.7 1.8 2 0 0 2 2 2 0 Trimerisation motif DUF4208 PF13907.6 EKX50158.1 - 0.54 10.7 7.0 1.1 9.7 0.2 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4208) PCRF PF03462.18 EKX50158.1 - 0.58 10.0 5.7 0.11 12.3 1.6 1.8 2 0 0 2 2 2 0 PCRF domain Sof1 PF04158.14 EKX50159.1 - 5.8e-31 106.6 8.2 1e-30 105.8 8.2 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 EKX50159.1 - 1.3e-21 76.5 18.2 0.00012 22.8 0.2 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX50159.1 - 0.00066 19.9 0.2 5.5 7.4 0.0 4.1 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Bestrophin PF01062.21 EKX50160.1 - 1.3e-39 136.4 0.2 1.8e-39 135.9 0.2 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Glycolytic PF00274.19 EKX50160.1 - 0.06 12.1 0.0 0.12 11.1 0.0 1.5 1 1 0 1 1 1 0 Fructose-bisphosphate aldolase class-I Glyco_transf_4 PF13439.6 EKX50160.1 - 0.069 13.1 0.3 2.3 8.2 0.0 2.2 1 1 1 2 2 2 0 Glycosyltransferase Family 4 CAP_N PF01213.19 EKX50161.1 - 0.14 11.6 2.4 0.25 10.8 2.4 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Androgen_recep PF02166.16 EKX50161.1 - 0.16 10.8 4.1 0.25 10.1 4.1 1.3 1 0 0 1 1 1 0 Androgen receptor PRIMA1 PF16101.5 EKX50161.1 - 0.21 11.6 6.7 0.52 10.4 6.7 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Spo0A_C PF08769.11 EKX50162.1 - 0.089 12.9 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal PIN_8 PF18476.1 EKX50162.1 - 1.5 8.7 5.8 3.6 7.4 5.1 1.9 2 0 0 2 2 2 0 PIN like domain Orai-1 PF07856.12 EKX50164.1 - 0.00043 20.0 13.0 0.12 12.0 13.0 2.2 1 1 0 1 1 1 1 Mediator of CRAC channel activity Endonuc-BglII PF09195.11 EKX50164.1 - 0.083 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease BglII PHF5 PF03660.14 EKX50165.1 - 2.1e-50 169.2 12.8 2.4e-50 169.1 12.8 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 EKX50165.1 - 0.046 11.6 6.3 0.048 11.5 6.3 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 EKX50165.1 - 3.2 7.9 15.0 48 4.1 14.0 2.8 1 1 0 1 1 1 0 Double zinc ribbon Gly_transf_sug PF04488.15 EKX50166.1 - 3.6e-13 50.0 0.0 7.1e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 EKX50166.1 - 2.7e-06 26.9 1.7 0.0098 15.2 0.0 2.1 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.12 EKX50166.1 - 5.9e-05 22.6 0.0 0.00013 21.5 0.0 1.5 2 0 0 2 2 2 1 Capsular polysaccharide synthesis protein BiPBP_C PF06832.12 EKX50166.1 - 0.096 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family PAP_assoc PF03828.19 EKX50167.1 - 1e-17 64.1 0.3 4.8e-17 61.9 0.0 2.3 3 0 0 3 3 3 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EKX50167.1 - 2e-05 24.8 0.0 5.6e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_central PF04928.17 EKX50167.1 - 0.061 12.3 0.1 0.19 10.7 0.1 1.8 1 0 0 1 1 1 0 Poly(A) polymerase central domain Polbeta PF18765.1 EKX50167.1 - 0.15 12.2 0.1 0.48 10.5 0.0 1.9 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase DNMT1-RFD PF12047.8 EKX50168.1 - 0.0025 17.9 0.1 0.0082 16.2 0.1 2.0 1 1 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain DUF3629 PF12302.8 EKX50168.1 - 2.3 7.6 4.2 1.2 8.6 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3629) DUF1771 PF08590.10 EKX50170.1 - 0.11 12.9 0.1 0.3 11.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) Thioredoxin PF00085.20 EKX50171.1 - 1.2e-29 102.3 0.0 1.5e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EKX50171.1 - 8.9e-06 26.0 0.0 1.2e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 EKX50171.1 - 3.7e-05 23.5 0.0 5e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EKX50171.1 - 0.0001 22.7 0.2 0.00048 20.6 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 EKX50171.1 - 0.0012 18.6 0.0 0.017 14.9 0.1 2.1 1 1 1 2 2 2 1 Redoxin OST3_OST6 PF04756.13 EKX50171.1 - 0.0029 17.0 0.0 0.0034 16.8 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EKX50171.1 - 0.021 14.8 0.1 0.027 14.4 0.1 1.3 1 0 0 1 1 1 0 AhpC/TSA family Glutaredoxin PF00462.24 EKX50171.1 - 0.07 13.4 0.1 0.16 12.2 0.0 1.6 1 1 0 1 1 1 0 Glutaredoxin DUF3275 PF11679.8 EKX50171.1 - 0.095 12.7 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Thioredoxin_7 PF13899.6 EKX50171.1 - 0.12 12.5 0.2 0.12 12.5 0.2 2.0 2 1 0 2 2 2 0 Thioredoxin-like DIM1 PF02966.16 EKX50171.1 - 0.18 11.6 0.0 0.24 11.2 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 Peptidase_M13_N PF05649.13 EKX50172.1 - 8.5e-68 229.8 0.0 2.1e-67 228.5 0.0 1.7 3 0 0 3 3 3 1 Peptidase family M13 Peptidase_M13 PF01431.21 EKX50172.1 - 8.3e-42 143.1 0.2 1.5e-39 135.8 0.2 2.2 1 1 0 1 1 1 1 Peptidase family M13 RWP-RK PF02042.15 EKX50173.1 - 3.2e-10 39.8 0.0 7.1e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain GAF_2 PF13185.6 EKX50173.1 - 0.00065 20.0 0.0 0.0012 19.2 0.0 1.4 1 0 0 1 1 1 1 GAF domain bHLH-MYC_N PF14215.6 EKX50173.1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal EF-hand_8 PF13833.6 EKX50174.1 - 1.8e-07 30.9 1.2 0.0076 16.1 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX50174.1 - 6.7e-07 28.4 2.1 3.7e-05 23.0 0.1 3.2 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 EKX50174.1 - 2.9e-05 24.4 2.0 0.00021 21.7 0.8 3.1 2 0 0 2 2 2 1 EF-hand domain pair TPR_7 PF13176.6 EKX50174.1 - 5.8e-05 22.8 2.5 1.4 9.1 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX50174.1 - 0.00012 22.3 5.6 0.00086 19.5 2.9 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX50174.1 - 0.00043 20.5 0.6 0.0076 16.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX50174.1 - 0.00062 19.5 0.5 0.63 10.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX50174.1 - 0.00068 20.2 1.3 0.34 11.9 0.0 3.9 1 1 2 3 3 3 1 Tetratricopeptide repeat EF-hand_6 PF13405.6 EKX50174.1 - 0.0015 18.3 3.5 0.0066 16.3 0.2 3.2 3 0 0 3 3 3 1 EF-hand domain TPR_2 PF07719.17 EKX50174.1 - 0.0017 18.4 1.4 3.3 8.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat EF-hand_5 PF13202.6 EKX50174.1 - 0.0028 17.1 0.8 0.0097 15.4 0.1 2.3 2 0 0 2 2 2 1 EF hand TPR_16 PF13432.6 EKX50174.1 - 0.0028 18.3 0.4 0.53 11.0 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 EKX50174.1 - 0.03 14.4 0.5 0.82 9.8 0.1 3.1 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 EKX50174.1 - 0.047 14.2 0.3 0.2 12.2 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat SPC12 PF06645.13 EKX50175.1 - 2.1e-19 69.4 0.2 2.5e-19 69.1 0.2 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Glutaredoxin PF00462.24 EKX50178.1 - 0.0019 18.4 0.0 0.003 17.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N PF02798.20 EKX50178.1 - 0.11 12.8 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EKX50178.1 - 0.16 12.4 0.0 0.24 11.9 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ArfGap PF01412.18 EKX50180.1 - 0.016 15.3 1.3 0.075 13.1 1.3 2.2 1 1 0 1 1 1 0 Putative GTPase activating protein for Arf GD_AH_C PF04295.13 EKX50183.1 - 0.067 12.0 0.0 0.094 11.5 0.0 1.1 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus 2Fe-2S_thioredx PF01257.19 EKX50184.1 - 6.2e-55 185.0 0.1 9.5e-55 184.4 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Na_H_antiport_2 PF13726.6 EKX50185.1 - 0.15 12.2 4.6 2.1 8.5 0.1 2.5 2 1 0 2 2 2 0 Na+-H+ antiporter family Ank_4 PF13637.6 EKX50186.1 - 2.1e-29 101.5 1.8 2.8e-08 34.2 0.0 3.8 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX50186.1 - 7.4e-26 90.6 0.0 4e-14 53.0 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EKX50186.1 - 3.7e-23 80.9 0.0 7.4e-08 32.5 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EKX50186.1 - 4.8e-21 74.6 0.3 2.8e-07 30.7 0.0 3.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX50186.1 - 6.3e-20 69.2 0.0 3.2e-05 24.0 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Type_III_YscX PF09474.10 EKX50186.1 - 0.049 13.9 0.0 0.094 13.0 0.0 1.4 1 0 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) DUF4116 PF13475.6 EKX50187.1 - 3.5e-43 145.1 0.0 1.2e-12 47.3 0.0 4.1 1 1 3 5 5 5 5 Domain of unknown function (DUF4116) AfsA PF03756.13 EKX50187.1 - 0.051 13.6 0.0 0.14 12.2 0.0 1.7 1 1 0 1 1 1 0 A-factor biosynthesis hotdog domain Tropomyosin_1 PF12718.7 EKX50188.1 - 0.015 15.4 22.2 0.015 15.4 22.2 5.3 1 1 3 4 4 4 0 Tropomyosin like HSBP1 PF06825.12 EKX50188.1 - 0.2 11.5 6.9 0.95 9.4 1.2 3.7 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Sugarporin_N PF11471.8 EKX50188.1 - 9.8 6.2 16.3 2.9 7.9 2.4 3.8 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension Methyltr_RsmB-F PF01189.17 EKX50189.1 - 1.1e-37 129.7 0.0 1.2e-36 126.3 0.0 2.1 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 EKX50189.1 - 3.6e-05 23.6 0.0 0.00018 21.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PUA PF01472.20 EKX50189.1 - 0.00031 20.6 0.3 0.001 19.0 0.0 2.0 2 0 0 2 2 2 1 PUA domain Methyltransf_25 PF13649.6 EKX50189.1 - 0.00034 21.3 0.0 0.0013 19.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 EKX50189.1 - 0.001 18.6 0.0 0.0034 17.0 0.0 1.8 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 EKX50189.1 - 0.01 15.5 0.0 0.14 11.7 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical protein 95 PCMT PF01135.19 EKX50189.1 - 0.016 15.0 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NESP55 PF06390.12 EKX50189.1 - 0.05 13.2 4.9 0.081 12.5 4.9 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) FtsJ PF01728.19 EKX50189.1 - 0.05 13.7 0.0 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase Got1 PF04178.12 EKX50190.1 - 1.4e-09 38.4 7.3 1.8e-09 38.0 7.3 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Phi_1 PF04674.12 EKX50191.1 - 0.041 13.2 0.1 0.053 12.8 0.1 1.1 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region Tox-SGS PF15651.6 EKX50191.1 - 0.13 12.5 0.1 0.2 11.9 0.1 1.3 1 0 0 1 1 1 0 Salivary glad secreted protein domain toxin EAP30 PF04157.16 EKX50192.1 - 1.6e-56 191.2 0.1 1.9e-56 191.0 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Exo70 PF03081.15 EKX50192.1 - 0.018 14.1 0.7 0.029 13.4 0.7 1.3 1 0 0 1 1 1 0 Exo70 exocyst complex subunit DUF19 PF01579.18 EKX50192.1 - 0.11 12.3 1.0 0.24 11.2 0.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF19) TTL PF03133.15 EKX50193.1 - 5.8e-27 94.6 0.0 1.2e-26 93.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family TFIIE-A_C PF11521.8 EKX50193.1 - 4.4 7.7 10.1 1.2 9.5 3.7 3.1 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha EF-hand_7 PF13499.6 EKX50195.1 - 2.1e-15 56.9 1.9 1.5e-06 28.6 0.0 4.1 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EKX50195.1 - 3.4e-15 54.4 8.8 4.6e-07 28.9 0.5 4.5 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 EKX50195.1 - 9.2e-12 44.6 10.8 0.0007 19.4 0.0 4.4 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.6 EKX50195.1 - 1.6e-11 43.1 5.4 8.3e-06 25.3 0.1 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EKX50195.1 - 3.1e-09 35.9 1.7 0.0015 17.9 0.1 3.6 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 EKX50195.1 - 2.2e-06 27.6 1.3 0.052 13.5 0.1 3.5 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SHOCT PF09851.9 EKX50195.1 - 0.006 16.3 0.1 0.25 11.2 0.0 2.5 2 0 0 2 2 2 1 Short C-terminal domain T-box PF00907.22 EKX50195.1 - 0.046 14.0 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 T-box SPARC_Ca_bdg PF10591.9 EKX50195.1 - 0.11 12.9 0.0 0.31 11.4 0.0 1.8 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region ParD_antitoxin PF03693.14 EKX50196.1 - 0.012 16.0 2.9 0.046 14.1 0.2 2.5 2 2 0 2 2 2 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH SlyX PF04102.12 EKX50196.1 - 0.093 13.4 11.5 0.92 10.2 1.4 2.8 3 0 0 3 3 3 0 SlyX XhlA PF10779.9 EKX50196.1 - 0.22 11.8 4.7 1.2 9.3 2.3 2.4 2 0 0 2 2 2 0 Haemolysin XhlA P66_CC PF16563.5 EKX50196.1 - 1.6 8.4 8.5 1.3 8.7 0.3 3.3 3 0 0 3 3 3 0 Coiled-coil and interaction region of P66A and P66B with MBD2 Fib_alpha PF08702.10 EKX50196.1 - 2 8.6 4.8 14 5.8 3.4 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family bZIP_2 PF07716.15 EKX50196.1 - 2.7 8.1 9.4 3.4 7.8 0.3 3.0 3 1 0 3 3 3 0 Basic region leucine zipper ABC_tran_CTD PF16326.5 EKX50196.1 - 6 7.2 12.9 0.73 10.1 0.7 2.9 3 1 0 3 3 3 0 ABC transporter C-terminal domain DUF641 PF04859.12 EKX50196.1 - 8.2 6.8 9.8 7.9 6.8 1.2 2.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) CDC73_C PF05179.14 EKX50197.1 - 8.1e-42 142.6 1.2 1.6e-41 141.6 1.2 1.5 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 EKX50197.1 - 8e-17 61.5 0.6 3.7e-16 59.3 0.6 2.0 1 1 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal Phytase-like PF13449.6 EKX50198.1 - 5.3e-17 62.7 0.0 2e-05 24.7 0.0 3.1 2 1 1 3 3 3 3 Esterase-like activity of phytase COX2-transmemb PF09125.10 EKX50198.1 - 0.8 9.5 2.0 24 4.8 0.0 2.5 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane T3SS_basalb_I PF17001.5 EKX50200.1 - 0.75 10.4 5.6 10 6.8 0.1 2.7 1 1 1 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI T3SS_basalb_I PF17001.5 EKX50202.1 - 0.0018 18.8 19.3 9.1 7.0 0.2 5.4 1 1 4 5 5 5 4 Type III secretion basal body protein I, YscI, HrpB, PscI DUF1090 PF06476.12 EKX50202.1 - 0.0069 16.5 58.7 0.16 12.1 5.7 5.9 1 1 5 6 6 6 5 Protein of unknown function (DUF1090) AAA_22 PF13401.6 EKX50202.1 - 0.075 13.3 0.0 0.37 11.1 0.0 2.2 1 1 0 1 1 1 0 AAA domain T3SS_basalb_I PF17001.5 EKX50204.1 - 0.018 15.6 12.1 7.1 7.3 0.2 3.8 1 1 2 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI AAA_22 PF13401.6 EKX50204.1 - 0.078 13.3 0.0 0.33 11.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain DUF1090 PF06476.12 EKX50204.1 - 3.7 7.7 38.8 0.68 10.1 7.8 4.3 1 1 3 4 4 4 0 Protein of unknown function (DUF1090) MFS_1 PF07690.16 EKX50205.1 - 1.5e-33 116.2 0.0 1.9e-33 115.9 0.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EKX50205.1 - 4.2e-13 48.9 1.3 7.2e-13 48.1 1.3 1.3 1 1 0 1 1 1 1 MFS_1 like family MFS_2 PF13347.6 EKX50205.1 - 1.7e-08 33.4 2.1 7.6e-08 31.3 2.1 1.8 1 1 0 1 1 1 1 MFS/sugar transport protein OATP PF03137.20 EKX50205.1 - 2.8e-08 32.5 4.8 0.00015 20.2 0.1 2.8 1 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 EKX50205.1 - 7.8e-07 28.3 4.1 1.5e-06 27.3 3.9 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter Nuc_H_symport PF03825.16 EKX50205.1 - 0.00021 20.4 3.1 0.0025 16.8 1.7 2.0 2 0 0 2 2 2 1 Nucleoside H+ symporter MFS_4 PF06779.14 EKX50205.1 - 0.002 17.5 6.3 0.006 15.9 5.5 2.1 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB AATase PF07247.12 EKX50205.1 - 0.018 13.6 0.1 0.026 13.1 0.1 1.1 1 0 0 1 1 1 0 Alcohol acetyltransferase FAM176 PF14851.6 EKX50205.1 - 0.079 12.6 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 FAM176 family CbiM PF01891.16 EKX50205.1 - 9.6 6.0 12.2 0.89 9.3 1.3 3.1 2 1 1 3 3 3 0 Cobalt uptake substrate-specific transmembrane region Ank_4 PF13637.6 EKX50206.1 - 1.7e-08 34.8 1.1 0.00014 22.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX50206.1 - 5.9e-06 26.8 0.6 4e-05 24.1 0.3 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EKX50206.1 - 4.8e-05 23.6 0.1 0.26 11.8 0.2 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EKX50206.1 - 0.0057 16.9 0.1 0.78 10.1 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX50206.1 - 0.0087 16.5 0.0 51 4.9 0.1 3.4 3 0 0 3 3 3 0 Ankyrin repeat FdtA PF05523.11 EKX50206.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 WxcM-like, C-terminal Glyco_transf_41 PF13844.6 EKX50208.1 - 1.5e-53 182.0 0.0 5.9e-36 123.9 0.0 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_2 PF07719.17 EKX50208.1 - 4e-15 54.6 0.7 0.0019 18.2 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 EKX50208.1 - 7e-12 44.6 0.1 0.043 13.7 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX50208.1 - 2.1e-10 41.1 5.5 3.8e-05 24.3 0.0 4.3 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX50208.1 - 2.4e-08 33.6 0.0 1.3 9.4 0.0 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX50208.1 - 7.1e-08 32.0 0.0 0.00022 20.9 0.0 3.5 2 1 1 3 3 3 2 TPR repeat TPR_19 PF14559.6 EKX50208.1 - 2.5e-07 31.1 1.5 0.0011 19.4 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX50208.1 - 4.6e-07 30.0 10.8 4.7e-05 23.6 0.1 4.7 4 1 1 6 6 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX50208.1 - 5.5e-07 29.3 2.2 5.8 6.9 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX50208.1 - 5.7e-07 29.6 4.0 0.00057 20.0 0.1 4.6 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX50208.1 - 1.2e-06 28.8 12.0 0.066 14.1 0.0 6.4 4 1 3 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX50208.1 - 8.6e-06 25.4 0.1 10 6.4 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 EKX50208.1 - 3.3e-05 23.3 2.8 0.0017 17.6 0.0 3.5 3 2 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX50208.1 - 0.00069 19.8 0.5 0.01 16.0 0.1 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EKX50208.1 - 0.0089 16.3 0.0 0.28 11.6 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EKX50208.1 - 0.093 12.7 0.0 1.8 8.6 0.0 2.4 1 1 1 2 2 2 0 Putative TPR-like repeat Wzy_C_2 PF11846.8 EKX50208.1 - 0.11 12.4 0.2 0.88 9.5 0.0 2.5 2 1 0 3 3 2 0 Virulence factor membrane-bound polymerase, C-terminal PPR PF01535.20 EKX50208.1 - 0.52 10.7 2.1 1.5e+02 3.0 0.0 4.4 5 0 0 5 5 5 0 PPR repeat WD40 PF00400.32 EKX50209.1 - 4.4e-10 40.0 2.4 0.01 16.7 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat LRR_4 PF12799.7 EKX50209.1 - 0.0056 17.1 13.2 0.097 13.1 6.8 3.8 2 2 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX50209.1 - 0.76 9.6 11.4 2.5 8.0 9.1 3.1 2 1 1 3 3 3 0 Leucine rich repeat FAM117 PF15388.6 EKX50209.1 - 0.86 9.0 3.7 0.89 8.9 0.5 2.3 2 0 0 2 2 2 0 Protein Family FAM117 Prefoldin_3 PF13758.6 EKX50209.1 - 2.3 8.3 6.5 24 5.0 0.1 4.1 4 0 0 4 4 4 0 Prefoldin subunit LRR_6 PF13516.6 EKX50209.1 - 3.2 8.0 23.1 0.58 10.4 3.8 4.1 5 0 0 5 5 5 0 Leucine Rich repeat RWP-RK PF02042.15 EKX50210.1 - 1.5e-18 66.4 1.0 3.3e-18 65.4 1.0 1.6 1 0 0 1 1 1 1 RWP-RK domain DUF4618 PF15397.6 EKX50210.1 - 0.0077 15.7 1.8 0.015 14.7 1.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) Mod_r PF07200.13 EKX50210.1 - 0.021 15.0 5.4 0.021 15.0 5.4 1.6 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein PspA_IM30 PF04012.12 EKX50210.1 - 0.031 13.9 3.9 0.059 12.9 3.9 1.4 1 0 0 1 1 1 0 PspA/IM30 family Mak10 PF04112.13 EKX50210.1 - 0.042 13.3 0.0 0.083 12.4 0.0 1.5 1 1 0 1 1 1 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DUF737 PF05300.11 EKX50210.1 - 0.061 13.7 2.6 0.075 13.4 2.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF737) P4Ha_N PF08336.11 EKX50210.1 - 0.18 11.8 2.4 4.2 7.4 0.5 2.5 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region NIF PF03031.18 EKX50211.1 - 1.1e-35 122.7 0.1 3.4e-21 75.7 0.0 2.1 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Glyco_transf_10 PF00852.19 EKX50212.1 - 0.005 16.6 0.0 0.0087 15.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term eIF-5a PF01287.20 EKX50213.1 - 6.5e-27 93.4 1.3 9e-27 93.0 1.3 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EKX50213.1 - 0.0097 15.9 0.2 0.021 14.9 0.2 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain SprT-like PF10263.9 EKX50214.1 - 1.6e-26 92.4 0.0 2.1e-26 92.0 0.0 1.2 1 1 0 1 1 1 1 SprT-like family Peptidase_M91 PF14891.6 EKX50214.1 - 0.0072 16.7 0.0 0.0088 16.4 0.0 1.2 1 0 0 1 1 1 1 Effector protein Peptidase_M76 PF09768.9 EKX50214.1 - 0.011 15.6 0.1 0.025 14.4 0.1 1.7 1 1 1 2 2 2 0 Peptidase M76 family BSP PF04450.12 EKX50214.1 - 0.022 14.6 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase of plants and bacteria WLM PF08325.10 EKX50214.1 - 0.1 12.6 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 WLM domain NAD_binding_4 PF07993.12 EKX50215.1 - 1.8e-60 204.3 0.0 2.2e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.19 EKX50215.1 - 1.6e-22 79.6 1.2 3.2e-22 78.6 1.2 1.5 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EKX50215.1 - 3.3e-07 30.0 0.0 9.7e-07 28.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EKX50215.1 - 0.0001 21.4 0.0 0.00046 19.3 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EKX50215.1 - 0.00047 19.4 0.6 0.0021 17.2 0.6 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EKX50215.1 - 0.0011 18.1 0.3 0.022 13.9 0.2 2.5 3 0 0 3 3 3 1 RmlD substrate binding domain Semialdhyde_dh PF01118.24 EKX50215.1 - 0.09 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EKX50215.1 - 0.13 12.6 0.0 1.6 9.0 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 EKX50215.1 - 0.13 11.6 0.1 0.65 9.3 0.1 1.9 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase RPAP1_N PF08621.10 EKX50215.1 - 0.29 10.9 0.9 1 9.2 0.9 2.0 1 0 0 1 1 1 0 RPAP1-like, N-terminal AAA_31 PF13614.6 EKX50216.1 - 5.8e-19 68.7 0.1 6.5e-18 65.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 EKX50216.1 - 1.9e-11 44.1 0.0 1.9e-11 44.1 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 EKX50216.1 - 9.8e-05 21.9 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 EKX50216.1 - 0.0014 18.0 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 EKX50216.1 - 0.0024 17.3 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 EKX50216.1 - 0.0025 17.1 0.0 0.0085 15.3 0.0 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 EKX50216.1 - 0.0064 16.0 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 EKX50216.1 - 0.078 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Tfb2 PF03849.14 EKX50217.1 - 3.7e-60 203.8 0.0 7.8e-59 199.4 0.0 2.0 1 1 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 EKX50217.1 - 2.1e-09 37.7 0.0 8.1e-07 29.4 0.1 2.4 2 0 0 2 2 2 2 Transcription factor Tfb2 (p52) C-terminal domain Mt_ATP-synt_B PF05405.14 EKX50218.1 - 0.06 13.0 0.1 2.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Lipase_bact_N PF12262.8 EKX50218.1 - 0.14 11.5 0.3 0.17 11.2 0.3 1.1 1 0 0 1 1 1 0 Bacterial virulence factor lipase N-terminal MORN PF02493.20 EKX50219.1 - 1.4e-36 122.2 39.4 2.4e-09 36.5 0.9 10.1 10 0 0 10 10 10 9 MORN repeat HrpB7 PF09486.10 EKX50220.1 - 0.00049 20.5 18.2 0.00049 20.5 18.2 2.4 1 1 1 2 2 2 1 Bacterial type III secretion protein (HrpB7) MPS2 PF17060.5 EKX50220.1 - 0.027 13.7 3.7 0.034 13.4 3.7 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 GAS PF13851.6 EKX50220.1 - 0.065 12.6 14.3 0.042 13.2 9.2 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF641 PF04859.12 EKX50220.1 - 0.13 12.6 0.3 0.13 12.6 0.3 3.0 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) TolA_bind_tri PF16331.5 EKX50220.1 - 0.24 11.5 15.6 1.2 9.3 12.0 2.7 2 1 1 3 3 3 0 TolA binding protein trimerisation COG5 PF10392.9 EKX50220.1 - 0.47 10.6 3.7 0.5 10.5 0.9 2.4 3 0 0 3 3 3 0 Golgi transport complex subunit 5 AAA_13 PF13166.6 EKX50220.1 - 0.49 9.0 6.1 0.93 8.1 5.5 1.6 1 1 0 1 1 1 0 AAA domain PKcGMP_CC PF16808.5 EKX50220.1 - 0.68 9.8 12.7 3.1 7.7 6.1 3.3 3 1 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Coiled-coil_56 PF09813.9 EKX50220.1 - 1.2 9.3 7.1 0.62 10.2 1.8 2.6 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 56 Fez1 PF06818.15 EKX50220.1 - 1.5 9.2 21.5 3 8.3 20.7 1.8 1 1 0 1 1 1 0 Fez1 V_ATPase_I PF01496.19 EKX50220.1 - 1.5 6.6 6.7 1.7 6.5 6.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 EKX50220.1 - 3.2 6.7 14.0 5.2 6.1 14.0 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Csm1_N PF18504.1 EKX50220.1 - 3.4 8.1 11.4 1.7 9.0 3.5 3.0 2 1 1 3 3 3 0 Csm1 N-terminal domain FlaC_arch PF05377.11 EKX50220.1 - 6.7 7.2 8.3 3 8.3 0.9 3.1 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) COG2 PF06148.11 EKX50220.1 - 8 6.6 11.3 0.89 9.6 4.2 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Cut12 PF11500.8 EKX50220.1 - 8.2 6.4 15.9 3.9 7.4 8.2 2.6 1 1 1 2 2 2 0 Spindle pole body formation-associated protein SlyX PF04102.12 EKX50220.1 - 10 6.9 16.7 12 6.6 5.5 3.5 2 1 2 4 4 4 0 SlyX Thyroglobulin_1 PF00086.18 EKX50222.1 - 0.021 14.5 0.1 0.034 13.8 0.1 1.3 1 0 0 1 1 1 0 Thyroglobulin type-1 repeat Exostosin PF03016.15 EKX50224.1 - 2.7e-55 187.7 0.0 1.3e-54 185.5 0.0 2.0 2 0 0 2 2 2 1 Exostosin family TPR_8 PF13181.6 EKX50224.1 - 3.4e-16 58.0 5.5 6.9e-05 22.8 0.3 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EKX50224.1 - 1e-15 56.9 0.7 3.7e-05 23.8 0.0 4.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX50224.1 - 1.1e-15 56.4 6.9 0.00026 20.9 0.1 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX50224.1 - 4e-12 45.6 2.6 0.0007 19.2 0.4 5.2 4 1 1 5 5 5 2 TPR repeat TPR_14 PF13428.6 EKX50224.1 - 5.8e-12 45.4 4.7 0.00041 20.9 0.0 5.8 3 3 3 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX50224.1 - 2.2e-11 44.1 3.4 0.005 17.3 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX50224.1 - 6e-11 41.7 2.8 0.033 14.0 0.1 6.2 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX50224.1 - 2.6e-09 37.6 1.4 0.054 14.1 0.1 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX50224.1 - 3.6e-09 36.8 7.6 0.0025 18.1 0.0 4.7 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX50224.1 - 7.9e-06 25.6 5.5 0.77 9.7 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX50224.1 - 5.3e-05 23.6 3.2 4 8.3 0.2 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 EKX50224.1 - 0.00032 21.0 0.3 2.3 9.1 0.0 4.0 4 0 0 4 4 2 2 Tetratricopeptide repeat NARP1 PF12569.8 EKX50224.1 - 0.00043 19.3 4.5 0.0077 15.2 0.3 2.6 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 EKX50224.1 - 0.002 18.0 0.3 11 6.3 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.6 EKX50224.1 - 0.0078 15.7 1.6 0.014 14.8 1.6 1.5 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP ANAPC3 PF12895.7 EKX50224.1 - 0.014 15.6 1.5 0.79 10.0 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 APC_N_CC PF16689.5 EKX50224.1 - 0.12 12.4 0.5 0.89 9.7 0.3 2.5 3 0 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain TPR_9 PF13371.6 EKX50224.1 - 0.22 11.7 1.8 2.7 8.2 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 EKX50225.1 - 1.2e-55 188.8 0.0 3.7e-54 183.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX50225.1 - 1.5e-24 86.7 0.0 4.9e-21 75.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX50225.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EKX50225.1 - 0.067 12.5 0.0 0.32 10.3 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Choline_kinase PF01633.20 EKX50225.1 - 0.078 12.6 0.1 0.14 11.8 0.0 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase RWP-RK PF02042.15 EKX50226.1 - 6.4e-16 58.1 0.0 1.3e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain HA PF03457.14 EKX50228.1 - 1.1e-38 131.3 18.5 6.3e-19 68.1 0.1 4.2 4 0 0 4 4 4 4 Helicase associated domain Pkinase PF00069.25 EKX50229.1 - 2.2e-27 96.1 0.0 5.5e-17 62.0 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EKX50229.1 - 8.7e-14 51.4 0.0 2e-09 37.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase EF-hand_7 PF13499.6 EKX50229.1 - 4.7e-08 33.4 0.0 1e-07 32.3 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX50229.1 - 1e-06 27.9 0.2 0.00039 19.8 0.2 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX50229.1 - 0.00017 21.2 0.0 0.63 10.1 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain DUF4140 PF13600.6 EKX50229.1 - 0.0022 18.4 0.6 0.0047 17.3 0.6 1.5 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) EF-hand_9 PF14658.6 EKX50229.1 - 0.018 15.3 0.0 0.042 14.2 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain APH PF01636.23 EKX50229.1 - 0.061 13.2 0.1 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family EF-hand_8 PF13833.6 EKX50229.1 - 0.12 12.3 0.1 0.54 10.2 0.0 2.2 1 1 1 2 2 2 0 EF-hand domain pair FlxA PF14282.6 EKX50229.1 - 0.18 11.8 1.9 0.32 11.0 1.9 1.3 1 0 0 1 1 1 0 FlxA-like protein OmpH PF03938.14 EKX50229.1 - 0.7 10.2 4.9 1.3 9.4 4.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Bacteriocin_IIc PF10439.9 EKX50231.1 - 0.038 14.1 2.5 0.038 14.1 2.5 1.9 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide PadR PF03551.14 EKX50231.1 - 0.15 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF1445 PF07286.12 EKX50231.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1445) PAS_3 PF08447.12 EKX50232.1 - 4.1e-05 23.8 0.0 6.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 PAS fold HLH PF00010.26 EKX50232.1 - 5.2e-05 23.1 0.0 0.00014 21.8 0.0 1.7 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PAS_4 PF08448.10 EKX50232.1 - 0.00011 22.4 0.0 0.00057 20.1 0.0 2.3 1 1 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EKX50232.1 - 0.0024 17.9 0.0 0.0048 16.9 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EKX50232.1 - 0.0052 16.8 0.0 0.0095 15.9 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 EKX50232.1 - 0.15 12.4 0.0 0.34 11.2 0.0 1.6 2 0 0 2 2 2 0 PAS domain tRNA-synt_2b PF00587.25 EKX50234.1 - 2.6e-35 122.0 0.0 4.4e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EKX50234.1 - 8.1e-23 80.4 1.1 2.1e-22 79.0 1.1 1.8 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 EKX50234.1 - 2.7e-16 59.4 0.0 5.5e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 EKX50234.1 - 9.8e-11 41.6 0.0 2.1e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF1093 PF06486.11 EKX50234.1 - 0.048 14.3 0.2 0.11 13.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1093) RWD PF05773.22 EKX50235.1 - 2.2e-11 44.1 0.0 6.6e-11 42.5 0.0 1.8 1 1 0 1 1 1 1 RWD domain PTPRCAP PF15713.5 EKX50235.1 - 3.1 8.1 13.4 0.059 13.7 4.5 2.1 1 1 1 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated BUD22 PF09073.10 EKX50235.1 - 5.6 6.2 10.4 8.3 5.6 10.4 1.2 1 0 0 1 1 1 0 BUD22 Ribosomal_L36 PF00444.18 EKX50236.1 - 2.4e-12 46.8 10.0 3.4e-12 46.4 10.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 Yos9_DD PF17880.1 EKX50236.1 - 0.11 12.7 0.0 0.14 12.2 0.0 1.4 1 1 0 1 1 1 0 Yos9 dimerzation domain RAP1 PF07218.11 EKX50238.1 - 4.8 5.3 6.1 9.1 4.4 6.1 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) 3HCDH_N PF02737.18 EKX50239.1 - 2.6e-26 92.6 0.0 3.5e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-C3HC4_3 PF13920.6 EKX50239.1 - 1.9e-11 43.6 7.5 3.2e-11 42.9 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX50239.1 - 5.2e-08 33.1 8.7 1.2e-07 32.0 8.7 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EKX50239.1 - 5e-06 26.3 6.8 9.7e-06 25.4 6.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EKX50239.1 - 2.1e-05 24.3 9.4 2.1e-05 24.3 9.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX50239.1 - 3.2e-05 23.8 9.0 4.8e-05 23.2 7.7 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EKX50239.1 - 6.8e-05 22.6 9.2 0.00014 21.6 9.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) NAD_binding_2 PF03446.15 EKX50239.1 - 0.0094 16.1 0.1 0.016 15.3 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase zf-RING_4 PF14570.6 EKX50239.1 - 0.013 15.2 5.7 0.026 14.3 5.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.7 EKX50239.1 - 0.033 14.2 4.6 0.082 12.9 4.6 1.6 1 0 0 1 1 1 0 Double zinc ribbon ApbA PF02558.16 EKX50239.1 - 0.034 13.8 0.1 0.088 12.5 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 EKX50239.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EKX50239.1 - 0.12 11.7 0.4 0.24 10.8 0.3 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EKX50239.1 - 0.15 11.3 0.9 0.28 10.4 0.7 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-RING_UBOX PF13445.6 EKX50239.1 - 0.18 11.9 6.4 0.49 10.5 6.4 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 EKX50239.1 - 0.21 11.4 2.3 0.35 10.6 1.1 2.2 2 0 0 2 2 2 0 RING-like zinc finger zf-P11 PF03854.14 EKX50239.1 - 0.73 9.5 4.7 0.46 10.2 1.4 2.0 1 1 1 2 2 2 0 P-11 zinc finger DR2241 PF18069.1 EKX50240.1 - 0.0098 15.8 0.5 0.021 14.7 0.5 1.5 1 0 0 1 1 1 1 DR2241 stabilising domain DinI PF06183.13 EKX50241.1 - 0.011 16.1 0.3 37 4.7 0.0 3.9 3 0 0 3 3 3 0 DinI-like family PAH PF02671.21 EKX50241.1 - 0.038 14.2 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Paired amphipathic helix repeat TLV_coat PF00429.19 EKX50241.1 - 0.1 11.2 0.1 0.18 10.5 0.1 1.3 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) Syntaxin-6_N PF09177.11 EKX50241.1 - 0.32 11.6 6.6 3.8 8.1 0.5 3.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF5106 PF17127.4 EKX50241.1 - 0.36 11.1 3.2 0.66 10.3 0.1 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF5106) TMCO5 PF14992.6 EKX50241.1 - 4.2 6.9 9.2 1.5 8.3 4.8 2.3 2 0 0 2 2 2 0 TMCO5 family FapA PF03961.13 EKX50242.1 - 8.6 4.8 8.0 1.2 7.6 3.6 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A DEAD PF00270.29 EKX50243.1 - 7.3e-20 71.4 0.1 6.1e-18 65.2 0.1 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX50243.1 - 6.5e-18 65.1 0.0 1.4e-11 44.7 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain CarD_CdnL_TRCF PF02559.16 EKX50243.1 - 8.2e-12 45.7 0.1 1.9e-11 44.5 0.1 1.7 1 0 0 1 1 1 1 CarD-like/TRCF domain AAA_22 PF13401.6 EKX50243.1 - 0.0041 17.4 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EKX50243.1 - 0.0076 16.3 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 EKX50245.1 - 2.7e-14 53.2 8.3 2.9e-14 53.1 8.3 1.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX50245.1 - 2.9e-11 43.0 7.6 3.3e-11 42.8 7.6 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EKX50245.1 - 8.4e-11 41.4 6.6 8.4e-11 41.4 6.6 1.7 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 EKX50245.1 - 9.6e-09 35.0 6.8 1.2e-08 34.7 6.8 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX50245.1 - 3.3e-08 33.7 10.8 2.5e-07 30.9 10.8 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EKX50245.1 - 5.5e-07 29.5 2.0 5.5e-07 29.5 2.0 1.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EKX50245.1 - 3.3e-06 26.9 5.1 4.1e-06 26.5 5.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX50245.1 - 7.1e-06 25.9 6.0 8e-06 25.7 6.0 1.1 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EKX50245.1 - 0.00039 20.2 8.0 0.00065 19.5 8.1 1.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EKX50245.1 - 0.00077 19.0 5.4 0.0011 18.6 5.4 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type RINGv PF12906.7 EKX50245.1 - 0.0042 17.2 6.0 0.013 15.7 6.0 1.7 1 1 0 1 1 1 1 RING-variant domain zf-ANAPC11 PF12861.7 EKX50245.1 - 0.0044 17.0 5.6 0.0076 16.3 5.6 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 EKX50245.1 - 0.015 15.5 8.8 0.35 11.1 8.8 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.8 EKX50245.1 - 0.18 11.7 4.1 0.22 11.4 4.1 1.2 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit LRR_6 PF13516.6 EKX50246.1 - 6.8e-24 81.9 8.4 5.9e-05 22.8 0.0 6.2 6 0 0 6 6 6 6 Leucine Rich repeat LRR_4 PF12799.7 EKX50246.1 - 4.5e-08 33.3 6.8 0.031 14.7 0.4 4.4 3 2 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX50246.1 - 1.5e-05 24.7 12.1 0.013 15.3 2.9 4.4 2 2 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 EKX50246.1 - 0.00014 21.9 4.3 1.1 10.0 0.3 5.1 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.6 EKX50247.1 - 3.5e-12 45.3 1.2 0.0014 18.5 0.0 4.5 4 0 0 4 4 4 3 Leucine Rich repeat LRR_1 PF00560.33 EKX50247.1 - 0.047 14.3 4.1 30 5.7 0.0 3.9 3 1 1 4 4 4 0 Leucine Rich Repeat MORN PF02493.20 EKX50248.1 - 3.5e-30 102.1 38.3 4.2e-07 29.5 3.1 7.2 7 0 0 7 7 7 6 MORN repeat NHL PF01436.21 EKX50249.1 - 4e-19 67.6 5.0 6.6e-08 32.2 0.0 4.5 5 0 0 5 5 5 3 NHL repeat SGL PF08450.12 EKX50249.1 - 0.00078 19.1 0.0 0.32 10.6 0.0 3.0 2 1 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Phytase-like PF13449.6 EKX50249.1 - 0.0095 15.9 0.0 7 6.5 0.0 3.0 1 1 1 2 2 2 2 Esterase-like activity of phytase Lactonase PF10282.9 EKX50249.1 - 0.029 13.6 0.0 0.17 11.1 0.0 2.1 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller CN_hydrolase PF00795.22 EKX50250.1 - 6e-53 179.8 0.0 6e-52 176.6 0.0 1.9 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase DUF1995 PF09353.10 EKX50251.1 - 1.7e-17 64.1 0.2 2.6e-17 63.5 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) PHD PF00628.29 EKX50252.1 - 4.4e-05 23.3 8.5 0.00014 21.7 8.5 1.9 1 0 0 1 1 1 1 PHD-finger Myb_DNA-binding PF00249.31 EKX50252.1 - 0.0022 18.1 0.0 1.1 9.5 0.0 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain PWWP PF00855.17 EKX50252.1 - 0.032 14.6 0.1 0.29 11.6 0.0 2.7 2 0 0 2 2 2 0 PWWP domain Thioredoxin PF00085.20 EKX50253.1 - 3.9e-64 213.1 0.1 4.7e-31 106.8 0.0 2.9 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 EKX50253.1 - 1.2e-33 116.6 0.9 5.8e-24 85.0 0.1 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EKX50253.1 - 1.5e-10 41.5 7.5 7.6e-06 26.3 0.1 4.6 4 3 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EKX50253.1 - 1.6e-08 34.8 1.8 0.048 14.0 0.0 4.8 4 2 0 4 4 4 2 Thioredoxin-like OST3_OST6 PF04756.13 EKX50253.1 - 3.2e-08 33.3 0.1 0.0059 16.0 0.0 2.9 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family Calsequestrin PF01216.17 EKX50253.1 - 1.5e-07 30.8 0.2 2.6e-07 30.0 0.2 1.3 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_7 PF13899.6 EKX50253.1 - 8.1e-07 29.1 0.0 0.021 15.0 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like ERp29_N PF07912.13 EKX50253.1 - 2.8e-06 27.5 0.5 0.16 12.1 0.0 3.6 4 1 0 4 4 4 2 ERp29, N-terminal domain AhpC-TSA PF00578.21 EKX50253.1 - 3.3e-06 27.0 1.2 0.035 14.0 0.0 3.6 4 0 0 4 4 4 2 AhpC/TSA family Glutaredoxin PF00462.24 EKX50253.1 - 0.00035 20.7 0.4 2.1 8.6 0.0 3.2 3 1 0 3 3 3 2 Glutaredoxin Thioredoxin_9 PF14595.6 EKX50253.1 - 0.00067 19.4 0.1 2 8.2 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_3 PF13192.6 EKX50253.1 - 0.0012 18.9 0.1 0.36 10.9 0.0 4.2 5 0 0 5 5 5 1 Thioredoxin domain Redoxin PF08534.10 EKX50253.1 - 0.0012 18.6 5.1 0.18 11.5 0.0 3.8 4 1 0 4 4 4 2 Redoxin TraF PF13728.6 EKX50253.1 - 0.013 15.4 0.0 2.1 8.1 0.0 3.0 3 0 0 3 3 3 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 EKX50253.1 - 0.035 14.3 0.2 20 5.3 0.0 3.3 2 1 1 3 3 3 0 Thioredoxin DUF1995 PF09353.10 EKX50254.1 - 5e-32 111.5 0.0 5.8e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) hSac2 PF12456.8 EKX50255.1 - 3.1e-11 43.0 0.0 5e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase DUF3095 PF11294.8 EKX50255.1 - 0.098 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3095) Poxvirus_B22R_C PF13168.6 EKX50255.1 - 5.1 6.5 11.5 4 6.9 2.4 2.7 1 1 2 3 3 3 0 Poxvirus B22R protein C-terminal TRAM_LAG1_CLN8 PF03798.16 EKX50256.1 - 2.7e-08 33.8 12.5 3.7e-05 23.6 1.6 2.4 1 1 1 2 2 2 2 TLC domain BRCT_2 PF16589.5 EKX50257.1 - 4.9e-10 39.7 0.0 4e-05 23.9 0.0 2.7 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EKX50257.1 - 5.6e-09 36.3 0.0 0.0005 20.4 0.0 2.9 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_3 PF18428.1 EKX50257.1 - 3.4e-06 27.1 0.0 0.0078 16.3 0.0 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain CxC6 PF18721.1 EKX50257.1 - 0.0032 17.7 2.2 0.0032 17.7 2.2 3.0 2 1 1 3 3 3 1 CxC6 like cysteine cluster associated with KDZ transposases GATA PF00320.27 EKX50257.1 - 0.011 15.4 1.4 0.11 12.2 0.2 2.8 2 0 0 2 2 2 0 GATA zinc finger RTT107_BRCT_5 PF16770.5 EKX50257.1 - 0.077 12.9 0.1 1.2 9.1 0.0 2.8 3 0 0 3 3 3 0 Regulator of Ty1 transposition protein 107 BRCT domain RlaP PF10127.9 EKX50258.1 - 0.065 12.8 1.5 0.099 12.2 1.5 1.2 1 0 0 1 1 1 0 RNA repair pathway DNA polymerase beta family DUF3245 PF11595.8 EKX50258.1 - 0.11 12.9 4.5 0.076 13.5 1.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) eIF-5a PF01287.20 EKX50259.1 - 6.5e-27 93.4 1.3 9e-27 93.0 1.3 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EKX50259.1 - 0.0097 15.9 0.2 0.021 14.9 0.2 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Pkinase_Tyr PF07714.17 EKX50260.1 - 9.2e-53 179.2 0.0 1.3e-52 178.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX50260.1 - 9.2e-49 166.2 0.0 1.3e-48 165.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EKX50260.1 - 0.002 17.0 0.0 0.0031 16.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX50260.1 - 0.0027 17.6 0.1 0.013 15.4 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EKX50260.1 - 0.005 16.2 0.0 0.016 14.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EKX50260.1 - 0.013 14.9 0.1 0.021 14.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EKX50260.1 - 0.063 12.2 0.9 0.22 10.4 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain Bact_lectin PF18483.1 EKX50261.1 - 1.2e-19 71.1 0.0 2.3e-19 70.2 0.0 1.4 1 1 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 EKX50261.1 - 7.9e-14 51.8 0.1 4.9e-13 49.2 0.1 1.9 1 1 0 1 1 1 1 Legume lectin domain Lectin_leg-like PF03388.13 EKX50261.1 - 0.085 12.2 0.0 4.5 6.5 0.0 2.3 2 0 0 2 2 2 0 Legume-like lectin family Pkinase PF00069.25 EKX50264.1 - 1.3e-58 198.5 0.0 1.7e-58 198.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX50264.1 - 6.2e-30 104.4 0.0 8.2e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX50264.1 - 2.7e-05 23.7 0.0 5.7e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EKX50264.1 - 0.00095 18.0 0.0 0.0015 17.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EKX50264.1 - 0.042 12.9 0.0 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 EKX50264.1 - 0.12 12.0 0.1 6.4 6.3 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EKX50264.1 - 0.18 11.7 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family TPR_1 PF00515.28 EKX50265.1 - 1.6e-18 65.6 8.0 0.00071 19.3 0.0 6.5 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EKX50265.1 - 1.8e-13 49.5 11.4 0.00049 20.0 0.0 7.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX50265.1 - 6.8e-09 35.9 8.6 0.0029 17.9 0.1 4.4 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 EKX50265.1 - 2.1e-08 33.7 3.2 0.03 14.5 0.0 5.3 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX50265.1 - 3.1e-08 33.5 0.0 0.0015 18.7 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX50265.1 - 2.5e-06 27.1 1.9 0.033 13.9 0.0 5.7 7 1 1 8 8 8 1 TPR repeat TPR_16 PF13432.6 EKX50265.1 - 4.7e-06 27.2 10.1 0.0058 17.2 1.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX50265.1 - 4.8e-05 23.1 8.2 0.49 10.5 0.0 4.9 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX50265.1 - 0.001 19.7 18.9 0.37 11.7 0.1 6.7 5 2 3 8 8 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 EKX50265.1 - 0.0062 16.7 5.8 5.7 7.2 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX50265.1 - 0.0072 16.2 8.3 0.19 11.7 0.2 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX50265.1 - 0.025 15.1 3.7 2.7 8.6 0.3 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat EzrA PF06160.12 EKX50265.1 - 0.11 10.7 0.5 0.18 9.9 0.5 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TPR_6 PF13174.6 EKX50265.1 - 3.8 8.4 7.6 17 6.3 0.2 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat Sua5_yciO_yrdC PF01300.18 EKX50266.1 - 3.2e-34 118.0 0.0 4e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Telomere recombination PDZ_6 PF17820.1 EKX50267.1 - 5.3e-10 39.0 0.1 7.4e-10 38.5 0.1 1.2 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX50267.1 - 0.00083 19.7 0.0 0.0013 19.1 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX50267.1 - 0.023 14.7 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Tricorn protease PDZ domain DUF1659 PF07872.11 EKX50268.1 - 0.096 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1659) RNase_PH PF01138.21 EKX50269.1 - 3.3e-05 24.4 0.0 0.0011 19.5 0.0 2.3 2 0 0 2 2 2 2 3' exoribonuclease family, domain 1 UQ_con PF00179.26 EKX50270.1 - 1.9e-12 47.0 0.0 2e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EKX50270.1 - 0.072 13.4 0.0 0.091 13.1 0.0 1.2 1 0 0 1 1 1 0 RWD domain NuA4 PF09340.10 EKX50271.1 - 8.7e-26 89.6 1.3 1.6e-25 88.7 1.3 1.4 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Leg1 PF05612.12 EKX50271.1 - 0.056 12.6 0.0 0.057 12.6 0.0 1.1 1 0 0 1 1 1 0 Leg1 Enkurin PF13864.6 EKX50271.1 - 0.16 12.4 0.8 0.16 12.4 0.8 2.2 2 1 0 2 2 2 0 Calmodulin-binding ABC_tran PF00005.27 EKX50273.1 - 1.3e-07 32.2 0.1 3.7e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EKX50273.1 - 5e-07 29.8 0.0 1.1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system GDWWSH PF15667.5 EKX50273.1 - 0.028 13.8 0.4 0.041 13.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function with motif GDWWSH SbcCD_C PF13558.6 EKX50273.1 - 0.09 13.0 0.3 14 6.0 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC2_membrane_3 PF12698.7 EKX50274.1 - 5.8e-23 81.5 20.9 6.4e-23 81.4 20.9 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 EKX50275.1 - 4.6e-29 101.7 0.0 6.8e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EKX50275.1 - 1.3e-11 44.9 0.0 4.6e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EKX50275.1 - 4e-07 29.7 0.1 0.0019 17.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EKX50275.1 - 0.00015 22.3 0.0 0.00027 21.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EKX50275.1 - 0.00019 21.4 0.2 0.00048 20.1 0.1 1.6 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EKX50275.1 - 0.00047 19.8 0.1 0.00086 19.0 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF815 PF05673.13 EKX50275.1 - 0.0014 17.9 0.1 0.035 13.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_15 PF13175.6 EKX50275.1 - 0.0024 17.7 0.0 0.042 13.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 EKX50275.1 - 0.0033 17.5 0.2 0.02 15.0 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EKX50275.1 - 0.0071 16.7 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain SbcCD_C PF13558.6 EKX50275.1 - 0.0081 16.4 0.0 0.099 12.9 0.0 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 EKX50275.1 - 0.0095 15.7 0.1 0.066 12.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.7 EKX50275.1 - 0.083 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.6 EKX50275.1 - 0.095 13.0 0.2 1.2 9.4 0.0 2.3 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EKX50275.1 - 0.11 12.6 0.3 0.44 10.6 0.2 1.8 2 0 0 2 2 2 0 Dynamin family IstB_IS21 PF01695.17 EKX50275.1 - 0.12 12.1 0.0 2.8 7.6 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 EKX50275.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.5 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 EKX50275.1 - 0.19 11.3 0.2 0.34 10.4 0.2 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B OmpH PF03938.14 EKX50276.1 - 0.038 14.3 1.8 0.054 13.8 1.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF5069 PF16798.5 EKX50276.1 - 0.057 13.6 0.3 0.088 13.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5069) UBN_AB PF14075.6 EKX50276.1 - 0.09 12.5 1.5 0.12 12.1 1.5 1.2 1 0 0 1 1 1 0 Ubinuclein conserved middle domain DUF1598 PF07643.11 EKX50276.1 - 0.13 12.5 0.2 0.38 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1598) DUF2358 PF10184.9 EKX50278.1 - 9.8e-20 70.9 0.0 1.1e-19 70.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 EKX50278.1 - 0.0001 22.9 0.0 0.00012 22.6 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SOUL PF04832.12 EKX50279.1 - 2.2e-06 28.0 0.0 2.6e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 SOUL heme-binding protein Ubiq-Cytc-red_N PF09165.10 EKX50281.1 - 0.072 14.0 0.1 0.29 12.0 0.1 2.0 1 0 0 1 1 1 0 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal Glyco_transf_41 PF13844.6 EKX50282.1 - 1.2e-05 23.9 0.0 1.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 41 EF-hand_1 PF00036.32 EKX50283.1 - 2.1e-19 67.5 6.7 4.5e-06 25.8 0.0 4.6 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EKX50283.1 - 2e-14 53.2 7.4 1.8e-07 30.9 0.1 4.4 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EKX50283.1 - 5.7e-13 47.7 5.4 1.5e-05 24.5 0.0 4.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 EKX50283.1 - 1.1e-12 48.1 10.5 1.1e-09 38.7 0.1 4.3 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX50283.1 - 1.6e-11 43.1 9.2 0.00021 20.6 0.1 4.7 4 0 0 4 4 4 2 EF hand Pox_A_type_inc PF04508.12 EKX50283.1 - 0.00025 20.8 1.3 0.001 18.8 1.3 2.1 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat SPARC_Ca_bdg PF10591.9 EKX50283.1 - 0.00049 20.4 0.0 0.00049 20.4 0.0 2.7 2 1 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EKX50283.1 - 0.0019 18.5 0.0 0.012 15.9 0.0 2.4 3 0 0 3 3 2 1 EF-hand domain Ank_3 PF13606.6 EKX50283.1 - 0.012 16.1 0.0 0.9 10.3 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 EKX50283.1 - 0.023 15.3 0.0 0.056 14.0 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Dockerin_1 PF00404.18 EKX50283.1 - 0.042 14.1 0.0 0.84 9.9 0.0 2.5 2 0 0 2 2 2 0 Dockerin type I domain EF-hand_4 PF12763.7 EKX50283.1 - 0.088 12.8 0.3 1.2 9.2 0.1 2.5 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Ank_5 PF13857.6 EKX50283.1 - 0.19 12.1 0.0 0.44 10.9 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank PF00023.30 EKX50283.1 - 0.25 11.9 0.7 0.78 10.3 0.1 2.2 2 0 0 2 2 2 0 Ankyrin repeat Bax1-I PF01027.20 EKX50284.1 - 8.2e-33 114.0 36.2 4.3e-31 108.4 36.2 2.1 1 1 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2569 PF10754.9 EKX50284.1 - 5 7.6 18.1 0.13 12.7 5.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2569) Pkinase PF00069.25 EKX50285.1 - 1.9e-62 211.0 0.0 2.2e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX50285.1 - 2.8e-31 108.8 0.0 3.5e-31 108.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX50285.1 - 3.7e-05 23.2 0.0 0.0027 17.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like FTA2 PF13095.6 EKX50285.1 - 0.00084 19.0 0.0 0.51 9.9 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 EKX50285.1 - 0.024 13.7 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 EKX50285.1 - 0.076 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EKX50285.1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Zip PF02535.22 EKX50286.1 - 5.4 6.1 16.8 6.9 5.8 16.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.12 EKX50286.1 - 5.5 5.1 65.1 9.7 4.3 65.1 1.3 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 EKX50286.1 - 7.9 5.1 22.4 8.5 5.0 22.4 1.0 1 0 0 1 1 1 0 Presenilin Methyltransf_3 PF01596.17 EKX50287.1 - 9.8e-49 165.4 0.0 1.1e-48 165.3 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EKX50287.1 - 1.6e-15 58.1 0.0 2.1e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX50287.1 - 4.4e-05 23.3 0.0 5.9e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX50287.1 - 4.8e-05 24.0 0.0 0.00011 22.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EKX50287.1 - 0.00016 21.5 0.0 0.0002 21.2 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 EKX50287.1 - 0.00079 19.4 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EKX50287.1 - 0.02 14.2 0.0 0.037 13.3 0.0 1.3 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase GCD14 PF08704.10 EKX50287.1 - 0.16 11.6 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Nudix_hydro PF18290.1 EKX50288.1 - 4.1e-28 97.2 0.0 8.6e-28 96.2 0.0 1.6 1 0 0 1 1 1 1 Nudix hydrolase domain NUDIX PF00293.28 EKX50288.1 - 3.1e-17 62.9 0.1 4.4e-17 62.4 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain 2_5_RNA_ligase2 PF13563.6 EKX50288.1 - 0.13 12.1 0.1 0.28 11.1 0.0 1.6 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily CENP-F_leu_zip PF10473.9 EKX50290.1 - 6.3e-05 23.0 13.2 6.3e-05 23.0 13.2 5.1 2 1 3 5 5 5 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.7 EKX50290.1 - 0.0069 16.5 12.9 0.0069 16.5 12.9 4.9 2 1 3 5 5 5 2 Tropomyosin like Phasin_2 PF09361.10 EKX50290.1 - 0.0084 16.4 4.4 0.0084 16.4 4.4 3.2 3 2 0 3 3 3 1 Phasin protein Atg14 PF10186.9 EKX50290.1 - 0.019 14.0 0.2 0.019 14.0 0.2 3.5 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 ApoB100_C PF12491.8 EKX50290.1 - 0.036 14.0 0.6 0.3 11.1 0.1 2.5 2 0 0 2 2 2 0 Apolipoprotein B100 C terminal IFT57 PF10498.9 EKX50290.1 - 0.059 12.3 40.7 0.059 12.3 18.1 3.0 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 DUF4806 PF16064.5 EKX50290.1 - 0.18 12.1 2.7 0.53 10.6 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4806) KASH_CCD PF14662.6 EKX50290.1 - 0.43 10.4 60.1 0.087 12.7 24.5 4.4 1 1 3 5 5 5 0 Coiled-coil region of CCDC155 or KASH Fib_alpha PF08702.10 EKX50290.1 - 1.5 9.0 26.8 0.078 13.2 6.9 4.0 1 1 3 5 5 5 0 Fibrinogen alpha/beta chain family USP8_interact PF08941.10 EKX50290.1 - 1.7 8.4 28.3 0.19 11.5 0.6 4.6 2 2 2 4 4 4 0 USP8 interacting DUF730 PF05325.11 EKX50290.1 - 2.7 8.0 10.6 0.49 10.4 0.1 3.8 3 2 1 4 4 4 0 Protein of unknown function (DUF730) DUF4201 PF13870.6 EKX50290.1 - 4.1 7.1 50.6 0.88 9.3 20.7 4.7 2 1 3 5 5 5 0 Domain of unknown function (DUF4201) DUF1664 PF07889.12 EKX50290.1 - 6.9 6.7 27.8 17 5.5 1.0 4.7 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) SNF2_N PF00176.23 EKX50291.1 - 1.1e-47 162.5 0.0 1.1e-46 159.2 0.0 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX50291.1 - 2.3e-18 66.6 0.0 4.3e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX50291.1 - 2.9e-07 30.6 0.0 6.8e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EKX50291.1 - 0.0008 18.7 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Pkinase PF00069.25 EKX50292.1 - 7.1e-73 245.2 0.0 9.4e-73 244.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX50292.1 - 1.6e-33 116.1 0.0 2.1e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EKX50292.1 - 1.1e-07 31.2 0.2 1.5e-07 30.7 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EKX50292.1 - 3.3e-05 23.3 0.2 4.7e-05 22.8 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX50292.1 - 0.072 13.0 0.3 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family MORN PF02493.20 EKX50293.1 - 1.4e-43 144.2 74.8 1.8e-08 33.7 1.4 10.2 10 0 0 10 10 10 8 MORN repeat p25-alpha PF05517.12 EKX50293.1 - 0.00062 20.0 0.6 0.0017 18.5 0.1 2.1 2 0 0 2 2 2 1 p25-alpha YqgF PF14639.6 EKX50293.1 - 0.039 13.7 0.0 6.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Holliday-junction resolvase-like of SPT6 PseudoU_synth_2 PF00849.22 EKX50294.1 - 3.4e-18 66.2 0.0 6.7e-18 65.3 0.0 1.5 1 1 0 1 1 1 1 RNA pseudouridylate synthase EGF_CA PF07645.15 EKX50295.1 - 3e-13 49.7 22.6 3.7e-09 36.6 6.5 9.2 9 1 0 9 9 9 2 Calcium-binding EGF domain EGF_3 PF12947.7 EKX50295.1 - 7.6e-11 42.0 20.6 9.6e-08 32.1 9.7 9.4 10 1 1 11 11 11 2 EGF domain TSP_1 PF00090.19 EKX50295.1 - 4.6e-06 26.7 7.1 4.6e-06 26.7 7.1 6.3 6 0 0 6 6 6 2 Thrombospondin type 1 domain hEGF PF12661.7 EKX50295.1 - 4e-05 24.1 6.1 0.00031 21.2 1.4 10.1 12 0 0 12 12 12 2 Human growth factor-like EGF cEGF PF12662.7 EKX50295.1 - 0.00013 21.8 4.5 0.00013 21.8 4.5 10.3 9 2 2 11 11 11 2 Complement Clr-like EGF-like Ephrin_rec_like PF07699.13 EKX50295.1 - 0.016 15.0 0.1 0.016 15.0 0.1 9.0 5 2 3 8 8 8 0 Putative ephrin-receptor like Laminin_G_3 PF13385.6 EKX50295.1 - 0.021 15.0 0.2 0.075 13.2 0.3 1.9 2 0 0 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily EF-hand_7 PF13499.6 EKX50296.1 - 5.9e-16 58.7 5.3 2.1e-07 31.3 2.5 3.6 3 0 0 3 3 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX50296.1 - 3.9e-13 47.9 7.7 0.008 15.7 0.2 5.0 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EKX50296.1 - 2.9e-11 42.3 3.3 0.024 14.6 0.2 5.5 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 EKX50296.1 - 1.1e-08 34.8 9.1 0.0014 18.4 0.0 4.9 3 2 2 5 5 5 3 EF-hand domain pair LRR_6 PF13516.6 EKX50296.1 - 1.2e-06 28.0 12.6 0.044 13.8 0.4 5.2 5 0 0 5 5 5 2 Leucine Rich repeat EF-hand_5 PF13202.6 EKX50296.1 - 0.00061 19.2 11.5 3.6 7.3 0.4 4.9 5 0 0 5 5 5 3 EF hand DUF4476 PF14771.6 EKX50296.1 - 0.0043 17.3 0.0 0.1 12.9 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4476) LRR_4 PF12799.7 EKX50296.1 - 0.0058 17.0 14.1 0.083 13.4 5.1 4.0 1 1 1 3 3 3 2 Leucine Rich repeats (2 copies) Keratin_2_head PF16208.5 EKX50296.1 - 0.019 15.1 16.7 0.037 14.2 16.7 1.3 1 0 0 1 1 1 0 Keratin type II head LRR_1 PF00560.33 EKX50296.1 - 0.046 14.3 7.0 11 7.0 0.1 5.1 4 0 0 4 4 4 0 Leucine Rich Repeat Med26_C PF15693.5 EKX50296.1 - 0.49 10.5 1.9 15 5.7 0.0 2.8 3 0 0 3 3 3 0 Mediator complex subunit 26 C-terminal LRR_8 PF13855.6 EKX50296.1 - 2 8.3 16.4 1.8e+02 2.0 10.5 4.2 1 1 1 2 2 2 0 Leucine rich repeat KRTAP PF11759.8 EKX50296.1 - 5.1 7.7 15.4 11 6.7 15.4 1.4 1 0 0 1 1 1 0 Keratin-associated matrix GidB PF02527.15 EKX50297.1 - 0.005 16.2 0.0 0.0068 15.8 0.0 1.1 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Tim17 PF02466.19 EKX50298.1 - 4.1e-10 40.0 15.5 1.8e-09 37.9 15.3 2.0 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family ECF_trnsprt PF12822.7 EKX50298.1 - 0.0058 16.7 0.1 0.0073 16.4 0.1 1.1 1 0 0 1 1 1 1 ECF transporter, substrate-specific component GDP_Man_Dehyd PF16363.5 EKX50299.1 - 3.7e-61 207.4 0.0 4.3e-61 207.1 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EKX50299.1 - 7.5e-57 192.6 0.0 1e-56 192.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EKX50299.1 - 4.2e-16 58.9 0.1 4.1e-15 55.7 0.1 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EKX50299.1 - 2e-14 53.2 0.1 5.3e-14 51.9 0.1 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EKX50299.1 - 2.4e-14 53.1 0.0 3.9e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 EKX50299.1 - 3.5e-10 39.7 0.1 9.9e-10 38.2 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 EKX50299.1 - 1.8e-08 34.5 0.0 3.3e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EKX50299.1 - 5e-08 33.1 0.1 9.7e-08 32.1 0.1 1.4 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EKX50299.1 - 3.5e-06 26.8 0.0 6.3e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 EKX50299.1 - 4.6e-06 26.4 0.4 2.9e-05 23.8 0.2 2.1 2 0 0 2 2 2 1 NmrA-like family Pyr_redox_2 PF07992.14 EKX50299.1 - 0.0006 19.1 0.1 0.00096 18.5 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_4 PF07993.12 EKX50299.1 - 0.0013 17.9 0.2 0.0062 15.7 0.2 2.1 1 1 0 1 1 1 1 Male sterility protein 3HCDH_N PF02737.18 EKX50299.1 - 0.0021 17.9 0.1 0.005 16.8 0.1 1.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 EKX50299.1 - 0.03 14.9 0.1 0.067 13.7 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 EKX50299.1 - 0.037 13.6 0.2 0.062 12.9 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 EKX50299.1 - 0.1 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Asp PF00026.23 EKX50300.1 - 8e-37 127.3 0.0 1e-31 110.5 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EKX50300.1 - 1.5e-07 31.8 0.1 0.0001 22.6 0.0 2.5 2 1 0 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EKX50300.1 - 0.053 13.3 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Hat1_N PF10394.9 EKX50301.1 - 1.3e-17 64.5 0.0 3.5e-17 63.1 0.0 1.8 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 EKX50301.1 - 0.0011 19.2 0.0 0.0029 17.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EKX50301.1 - 0.0028 18.0 0.0 0.0075 16.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EKX50301.1 - 0.0092 15.9 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 EKX50301.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 MOZ/SAS family HTH_37 PF13744.6 EKX50301.1 - 0.65 10.0 2.8 2.4 8.2 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain FaeA PF04703.12 EKX50302.1 - 2.9e-05 24.3 0.0 0.0001 22.6 0.0 1.9 2 0 0 2 2 2 1 FaeA-like protein HTH_5 PF01022.20 EKX50302.1 - 0.003 17.4 0.0 0.009 15.9 0.0 1.8 1 1 1 2 2 2 1 Bacterial regulatory protein, arsR family TrmB PF01978.19 EKX50302.1 - 0.0042 16.9 0.1 0.013 15.4 0.1 1.9 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB HTH_IclR PF09339.10 EKX50302.1 - 0.0046 16.7 0.0 0.0095 15.7 0.0 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain DUF2431 PF10354.9 EKX50304.1 - 4.3e-49 167.0 0.0 6.8e-49 166.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) MTS PF05175.14 EKX50304.1 - 0.0051 16.4 0.0 0.0088 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EKX50304.1 - 0.019 14.4 0.1 0.033 13.7 0.1 1.4 1 0 0 1 1 1 0 Putative methyltransferase CCDC92 PF14916.6 EKX50304.1 - 0.031 14.0 0.4 0.1 12.4 0.1 1.9 2 0 0 2 2 2 0 Coiled-coil domain of unknown function GDP_Man_Dehyd PF16363.5 EKX50305.1 - 4.1e-59 200.6 0.0 4.8e-59 200.4 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EKX50305.1 - 2.1e-52 178.0 0.0 2.8e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EKX50305.1 - 6.3e-16 58.2 0.1 6.9e-15 54.8 0.1 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EKX50305.1 - 2.5e-12 46.5 0.0 3.2e-11 42.9 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EKX50305.1 - 5e-11 42.2 0.0 8.3e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 EKX50305.1 - 2.8e-07 30.6 0.0 5.1e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 EKX50305.1 - 2.1e-06 27.1 1.4 3.8e-05 23.0 1.4 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EKX50305.1 - 9e-05 22.4 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EKX50305.1 - 0.0069 15.9 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EKX50305.1 - 0.074 12.6 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Pro_CA PF00484.19 EKX50307.1 - 9.1e-42 143.0 0.2 1.1e-41 142.7 0.2 1.1 1 0 0 1 1 1 1 Carbonic anhydrase FKBP_C PF00254.28 EKX50308.1 - 9e-06 25.9 0.0 0.00042 20.6 0.0 2.6 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 EKX50308.1 - 0.0021 17.8 0.0 0.0076 16.0 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX50308.1 - 0.017 15.2 1.0 0.068 13.3 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX50308.1 - 0.019 15.0 0.1 0.043 13.9 0.1 1.6 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 EKX50308.1 - 0.05 13.6 0.3 0.4 10.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX50308.1 - 0.22 11.8 0.5 1.5 9.2 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX50308.1 - 0.27 12.1 4.4 0.39 11.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PDEase_I PF00233.19 EKX50309.1 - 5.1e-56 190.1 3.1 6.2e-56 189.8 3.1 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 EKX50309.1 - 0.089 13.0 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 HD domain EGF_CA PF07645.15 EKX50312.1 - 9.6e-13 48.1 24.0 1.1e-08 35.1 7.8 9.4 9 1 0 9 9 9 2 Calcium-binding EGF domain EGF_3 PF12947.7 EKX50312.1 - 1.8e-10 40.8 20.7 9.9e-08 32.1 9.7 9.4 10 1 0 10 10 10 2 EGF domain TSP_1 PF00090.19 EKX50312.1 - 2.3e-05 24.5 7.3 2.3e-05 24.5 7.3 6.3 7 0 0 7 7 7 2 Thrombospondin type 1 domain cEGF PF12662.7 EKX50312.1 - 0.00014 21.7 4.5 0.00014 21.7 4.5 10.8 10 2 2 12 12 12 2 Complement Clr-like EGF-like hEGF PF12661.7 EKX50312.1 - 0.00032 21.2 1.4 0.00032 21.2 1.4 10.0 12 0 0 12 12 12 2 Human growth factor-like EGF Ephrin_rec_like PF07699.13 EKX50312.1 - 0.016 14.9 0.1 0.016 14.9 0.1 9.0 5 2 1 7 7 7 0 Putative ephrin-receptor like DUF3598 PF12204.8 EKX50313.1 - 3e-05 23.7 0.1 0.21 11.1 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3598) Lyase_N PF09092.11 EKX50313.1 - 0.061 13.2 0.2 0.091 12.6 0.2 1.2 1 0 0 1 1 1 0 Lyase, N terminal Rad21_Rec8_N PF04825.13 EKX50314.1 - 4.8e-17 62.1 0.0 1.1e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EKX50314.1 - 1.4e-08 33.9 0.0 2.9e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 EKX50314.1 - 0.0017 18.3 0.0 0.0034 17.3 0.0 1.5 1 0 0 1 1 1 1 Segregation and condensation protein ScpA RSN1_7TM PF02714.15 EKX50315.1 - 5.5e-10 39.0 3.5 7.4e-10 38.6 3.5 1.1 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate Anoctamin PF04547.12 EKX50315.1 - 0.00025 20.1 0.8 0.00057 18.8 0.8 1.5 1 1 0 1 1 1 1 Calcium-activated chloride channel RCC1 PF00415.18 EKX50316.1 - 1.3e-42 144.2 13.2 1e-11 45.3 0.3 6.4 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX50316.1 - 2.7e-24 84.4 17.7 5.1e-07 29.3 1.6 6.4 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Kelch_2 PF07646.15 EKX50316.1 - 0.014 15.3 0.1 6.9 6.8 0.0 2.8 2 0 0 2 2 2 0 Kelch motif Ribosomal_L38e PF01781.18 EKX50317.1 - 5.3e-26 90.5 0.4 7.2e-26 90.1 0.4 1.2 1 0 0 1 1 1 1 Ribosomal L38e protein family SRF-TF PF00319.18 EKX50319.1 - 1.4e-21 75.7 0.1 1.7e-21 75.4 0.1 1.1 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Pkinase PF00069.25 EKX50320.1 - 2.7e-31 108.9 0.4 5.2e-29 101.4 0.0 3.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX50320.1 - 4.4e-20 72.0 0.1 3.9e-17 62.4 0.0 3.2 3 1 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 EKX50320.1 - 8.7e-06 25.2 0.0 1.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EKX50320.1 - 9.9e-05 21.3 0.0 0.00021 20.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX50320.1 - 0.11 12.4 0.1 0.29 11.0 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Ferritin PF00210.24 EKX50320.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 Ferritin-like domain PI3_PI4_kinase PF00454.27 EKX50321.1 - 1.1e-28 100.8 0.1 3.6e-14 53.2 0.0 3.1 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EKX50321.1 - 5.4e-06 26.1 0.2 1.9e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 FATC domain TPR_7 PF13176.6 EKX50321.1 - 6e-05 22.8 0.3 0.42 10.8 0.0 3.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX50321.1 - 0.00011 22.1 2.5 0.033 14.4 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX50321.1 - 0.0013 18.5 0.1 0.054 13.3 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX50321.1 - 0.0037 17.5 0.1 1.5 9.1 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX50321.1 - 0.0044 17.0 0.4 2.8 8.3 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX50321.1 - 0.026 15.3 0.1 1.3 10.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC5 PF12862.7 EKX50321.1 - 0.072 13.2 1.9 0.57 10.3 0.0 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 YicC_N PF03755.13 EKX50321.1 - 0.14 12.6 1.3 5.2 7.5 0.3 3.2 2 1 0 2 2 2 0 YicC-like family, N-terminal region Med2 PF11214.8 EKX50322.1 - 0.0066 16.6 0.1 0.04 14.1 0.1 2.4 1 0 0 1 1 1 1 Mediator complex subunit 2 HEAT PF02985.22 EKX50322.1 - 0.0076 16.4 0.2 0.26 11.7 0.1 3.0 2 0 0 2 2 2 1 HEAT repeat CdiI PF07262.11 EKX50323.1 - 0.037 13.8 2.7 0.067 13.0 2.7 1.5 1 1 0 1 1 1 0 CDI immunity protein VPS13_C PF16909.5 EKX50324.1 - 2.8e-39 134.7 0.1 5.9e-34 117.4 0.0 2.9 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 EKX50324.1 - 2.1e-38 132.3 0.0 6.5e-33 114.3 0.0 3.9 3 1 1 4 4 4 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 EKX50324.1 - 2.5e-26 92.9 1.8 2.5e-26 92.9 1.8 3.3 4 0 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 EKX50324.1 - 3.6e-16 59.3 0.3 1.4e-15 57.4 0.3 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EKX50324.1 - 1.1e-11 44.9 0.0 3.2e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain VPS13_mid_rpt PF16910.5 EKX50324.1 - 5.2e-09 35.9 0.0 8.9e-05 22.0 0.0 3.3 2 1 0 2 2 2 2 Repeating coiled region of VPS13 Thioredoxin_13 PF18401.1 EKX50324.1 - 0.0053 16.7 0.0 26 4.7 0.0 3.4 3 0 0 3 3 3 0 Thioredoxin-like domain RRM_1 PF00076.22 EKX50325.1 - 5.7e-20 70.9 0.0 8.1e-20 70.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EKX50325.1 - 2.9e-05 24.1 0.0 6.8e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif Mfp-3 PF04202.13 EKX50325.1 - 0.0017 18.7 3.8 0.0036 17.7 3.8 1.6 1 0 0 1 1 1 1 Foot protein 3 Limkain-b1 PF11608.8 EKX50325.1 - 0.0052 16.8 0.0 0.0087 16.1 0.0 1.4 1 0 0 1 1 1 1 Limkain b1 RRM_5 PF13893.6 EKX50325.1 - 0.0069 16.0 0.0 0.0095 15.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 EKX50325.1 - 0.03 14.2 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) RRM_occluded PF16842.5 EKX50325.1 - 0.095 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif GRP PF07172.11 EKX50325.1 - 0.29 11.8 8.1 0.11 13.2 2.6 2.2 2 0 0 2 2 2 0 Glycine rich protein family Torus PF16131.5 EKX50326.1 - 1.3e-32 112.7 2.5 2.1e-32 112.1 2.5 1.3 1 0 0 1 1 1 1 Torus domain zf-CCHC PF00098.23 EKX50326.1 - 2.1e-06 27.5 1.6 7.4e-06 25.8 1.6 1.9 1 0 0 1 1 1 1 Zinc knuckle RRM_1 PF00076.22 EKX50326.1 - 5.8e-06 26.0 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EKX50326.1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf_CCCH_4 PF18345.1 EKX50326.1 - 0.048 13.7 2.8 0.048 13.7 2.8 1.9 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH PF00642.24 EKX50326.1 - 5.3 7.1 10.7 0.52 10.3 5.7 1.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) UPF0515 PF15135.6 EKX50332.1 - 0.021 14.2 4.3 0.044 13.1 4.3 1.5 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 ColG_sub PF18496.1 EKX50332.1 - 0.021 15.0 2.8 0.046 13.9 2.8 1.6 1 0 0 1 1 1 0 Collagenase G catalytic helper subdomain Gly_acyl_tr_C PF08444.10 EKX50332.1 - 5.4 7.3 5.3 33 4.8 2.1 2.8 1 1 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region HNF-1_N PF04814.13 EKX50332.1 - 7.3 7.2 9.8 12 6.5 3.9 2.6 1 1 1 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus DHR10 PF18595.1 EKX50333.1 - 0.0042 17.1 6.7 0.0042 17.1 6.7 4.5 3 2 0 4 4 4 2 Designed helical repeat protein 10 domain DUF2203 PF09969.9 EKX50333.1 - 0.02 15.6 2.4 0.02 15.6 2.4 3.6 2 1 2 4 4 4 0 Uncharacterized conserved protein (DUF2203) DUF2200 PF09966.9 EKX50333.1 - 0.041 14.0 1.1 0.041 14.0 1.1 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2200) FRB_dom PF08771.11 EKX50333.1 - 0.067 13.6 21.6 0.16 12.4 0.4 3.9 4 0 0 4 4 4 0 FKBP12-rapamycin binding domain T2SSG PF08334.11 EKX50333.1 - 0.11 12.5 0.4 0.11 12.5 0.4 3.6 1 1 2 3 3 3 0 Type II secretion system (T2SS), protein G TENA_THI-4 PF03070.16 EKX50333.1 - 0.22 11.3 11.8 1.6 8.5 0.3 3.6 2 1 2 4 4 4 0 TENA/THI-4/PQQC family Seryl_tRNA_N PF02403.22 EKX50333.1 - 0.4 10.9 24.9 3 8.1 0.0 4.3 4 1 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.12 EKX50333.1 - 0.43 11.1 20.9 0.21 12.1 2.6 4.1 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF4763 PF15960.5 EKX50333.1 - 0.43 9.8 29.4 0.055 12.8 11.3 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4763) DUF948 PF06103.11 EKX50333.1 - 0.6 10.4 6.0 16 5.8 0.2 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Uds1 PF15456.6 EKX50333.1 - 0.92 9.7 23.5 0.085 13.0 0.6 3.7 2 1 0 3 3 3 0 Up-regulated During Septation Spc24 PF08286.11 EKX50333.1 - 1.5 9.1 30.0 0.61 10.4 4.0 4.3 3 1 1 4 4 4 0 Spc24 subunit of Ndc80 GAS PF13851.6 EKX50333.1 - 1.7 7.9 45.8 1.2 8.4 4.4 3.8 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding HrpB7 PF09486.10 EKX50333.1 - 1.9 8.8 11.8 1.3 9.4 2.6 3.1 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) Snapin_Pallidin PF14712.6 EKX50333.1 - 5.5 7.5 29.8 1.8 9.1 5.4 5.0 3 2 2 5 5 5 0 Snapin/Pallidin KASH_CCD PF14662.6 EKX50333.1 - 6.1 6.6 31.8 0.22 11.3 6.8 3.1 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH FA_desaturase PF00487.24 EKX50334.1 - 1e-34 120.6 32.0 2e-32 113.1 31.8 2.7 2 1 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 EKX50334.1 - 1.9e-06 27.9 0.1 7.9e-06 25.9 0.1 2.0 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_hydro_99 PF16317.5 EKX50335.1 - 2.1e-56 191.5 4.7 8e-32 110.7 0.4 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 99 Glyco_tran_WbsX PF14307.6 EKX50335.1 - 0.0011 18.6 2.6 0.0011 18.5 0.0 2.1 2 1 0 2 2 2 1 Glycosyltransferase WbsX Tnp_P_element PF12017.8 EKX50335.1 - 0.092 12.2 1.0 2 7.8 0.0 2.5 2 1 1 3 3 3 0 Transposase protein SAS4 PF15460.6 EKX50335.1 - 0.25 11.4 12.6 0.085 13.0 4.7 2.5 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 CENP-Q PF13094.6 EKX50335.1 - 6.4 7.0 12.0 0.57 10.4 7.1 1.7 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit LRR_6 PF13516.6 EKX50336.1 - 1.4e-20 71.5 33.5 0.00037 20.3 0.2 11.4 11 0 0 11 11 11 8 Leucine Rich repeat LRR_4 PF12799.7 EKX50336.1 - 1.8e-08 34.5 21.0 0.0044 17.4 0.1 7.5 4 2 4 8 8 8 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX50336.1 - 2e-06 27.5 31.5 0.071 12.9 2.8 8.2 3 2 5 8 8 8 6 Leucine rich repeat LRR_1 PF00560.33 EKX50336.1 - 0.0076 16.6 23.9 0.4 11.4 0.0 8.5 9 1 0 9 9 9 2 Leucine Rich Repeat Glyco_transf_64 PF09258.10 EKX50337.1 - 1.6e-19 70.2 0.1 2e-19 69.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain GCP_N_terminal PF17681.1 EKX50339.1 - 1.7e-73 247.9 0.1 3.5e-73 246.9 0.1 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EKX50339.1 - 6.9e-58 196.5 0.7 1.3e-57 195.6 0.7 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal G6PD_N PF00479.22 EKX50339.1 - 0.26 11.9 1.2 17 6.0 0.0 3.2 3 0 0 3 3 3 0 Glucose-6-phosphate dehydrogenase, NAD binding domain BCDHK_Adom3 PF10436.9 EKX50340.1 - 2.5e-42 144.5 0.5 4.6e-42 143.6 0.5 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EKX50340.1 - 2.3e-10 41.0 0.0 4.5e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EKX50340.1 - 0.0021 17.9 0.0 0.004 17.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Zip PF02535.22 EKX50341.1 - 2.8e-23 82.7 16.5 5.1e-22 78.5 3.7 2.3 2 0 0 2 2 2 2 ZIP Zinc transporter E1-E2_ATPase PF00122.20 EKX50341.1 - 0.0051 16.4 2.5 0.043 13.3 2.3 2.3 1 1 1 2 2 2 2 E1-E2 ATPase SyrA PF11089.8 EKX50341.1 - 0.0053 16.8 0.1 0.022 14.8 0.1 2.1 1 0 0 1 1 1 1 Exopolysaccharide production repressor Bac_rhodopsin PF01036.18 EKX50343.1 - 4.2e-25 88.6 6.9 5.5e-25 88.3 6.9 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein TssN PF17555.2 EKX50343.1 - 0.002 17.5 7.2 0.0025 17.3 6.6 1.4 1 1 0 1 1 1 1 Type VI secretion system, TssN DUF373 PF04123.13 EKX50343.1 - 0.46 9.9 3.6 0.81 9.1 3.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF373) EnY2 PF10163.9 EKX50344.1 - 5.3e-19 68.4 1.9 6.5e-19 68.1 1.9 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 Sin3a_C PF16879.5 EKX50344.1 - 0.036 13.8 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 C-terminal domain of Sin3a protein ERAP1_C PF11838.8 EKX50344.1 - 0.084 12.4 0.1 0.093 12.3 0.1 1.0 1 0 0 1 1 1 0 ERAP1-like C-terminal domain Tctex-1 PF03645.13 EKX50344.1 - 0.098 12.9 0.2 0.18 12.1 0.2 1.4 1 1 1 2 2 2 0 Tctex-1 family LupA PF18242.1 EKX50344.1 - 0.1 12.2 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Legionella ubiquitin-specific protease A domain PP2C_C PF07830.13 EKX50344.1 - 0.21 12.1 1.5 1.5 9.4 1.5 2.0 1 1 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain Zn_clus PF00172.18 EKX50345.1 - 1.8e-09 37.6 44.0 2.5e-07 30.7 11.0 3.1 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 EKX50346.1 - 1.1e-50 172.5 0.0 1.4e-50 172.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX50346.1 - 5.4e-32 111.1 0.0 7.7e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase VbhA PF18495.1 EKX50347.1 - 0.0027 17.5 0.6 0.079 12.8 0.0 2.4 2 0 0 2 2 2 2 Antitoxin VbhA Picorna_P3A PF06363.11 EKX50348.1 - 0.51 10.3 6.8 12 5.9 2.5 3.3 3 1 0 3 3 3 0 Picornaviridae P3A protein NFRKB_winged PF14465.6 EKX50348.1 - 0.58 10.4 3.7 0.46 10.7 1.5 2.0 2 0 0 2 2 2 0 NFRKB Winged Helix-like EOS1 PF12326.8 EKX50348.1 - 0.96 9.4 5.3 8.1 6.3 0.1 3.0 3 0 0 3 3 3 0 N-glycosylation protein CPSF100_C PF13299.6 EKX50348.1 - 1.5 9.0 16.2 1.1 9.4 11.2 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Merozoite_SPAM PF07133.11 EKX50348.1 - 3.8 7.5 29.1 0.47 10.4 24.6 1.7 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) AMPK1_CBM PF16561.5 EKX50349.1 - 7.5e-28 96.6 0.1 1.1e-27 96.1 0.1 1.2 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 EKX50349.1 - 3.7e-15 55.9 0.4 6.9e-15 55.1 0.4 1.5 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM_48 PF02922.18 EKX50349.1 - 0.0062 16.9 0.0 0.018 15.4 0.0 1.7 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Acetate_kinase PF00871.17 EKX50350.1 - 4.3e-143 476.7 0.0 4.9e-143 476.5 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family ROK PF00480.20 EKX50350.1 - 0.004 16.7 0.1 0.0064 16.0 0.1 1.2 1 0 0 1 1 1 1 ROK family PTA_PTB PF01515.19 EKX50351.1 - 2e-117 392.1 0.7 3.3e-117 391.4 0.7 1.4 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase DRTGG PF07085.12 EKX50351.1 - 3.9e-16 58.8 0.0 1.6e-15 56.8 0.1 2.1 2 0 0 2 2 2 1 DRTGG domain AAA_26 PF13500.6 EKX50351.1 - 1.6e-11 44.5 0.0 3.5e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain P-mevalo_kinase PF04275.14 EKX50351.1 - 0.16 11.9 0.0 0.42 10.6 0.0 1.6 1 1 0 1 1 1 0 Phosphomevalonate kinase TTL PF03133.15 EKX50352.1 - 6.3e-18 64.9 0.0 5.2e-17 61.9 0.0 2.1 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family HEAT_EZ PF13513.6 EKX50352.1 - 4.9e-17 62.1 7.0 0.00041 20.8 0.0 6.9 6 1 1 7 7 7 4 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EKX50352.1 - 2.3e-13 50.5 0.0 6.4e-05 23.5 0.0 4.8 3 1 2 5 5 4 3 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EKX50352.1 - 1.3e-12 47.9 3.5 0.021 15.2 0.0 5.3 2 2 1 4 4 4 4 HEAT repeats HEAT PF02985.22 EKX50352.1 - 1.2e-11 43.8 15.9 0.28 11.6 0.2 9.6 9 0 0 9 9 9 2 HEAT repeat IBN_N PF03810.19 EKX50352.1 - 6e-08 32.5 0.0 1.4e-06 28.1 0.0 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 EKX50352.1 - 1.4e-06 27.2 0.0 1.7e-05 23.6 0.0 2.5 2 1 0 3 3 3 1 Adaptin N terminal region ParcG PF10274.9 EKX50352.1 - 9.3e-05 22.6 0.3 1.6 8.8 0.0 3.9 3 1 1 4 4 4 3 Parkin co-regulated protein RIX1 PF08167.12 EKX50352.1 - 0.00036 20.3 0.0 3.7 7.2 0.0 3.9 2 2 2 4 4 4 2 rRNA processing/ribosome biogenesis DUF3385 PF11865.8 EKX50352.1 - 0.00066 19.6 0.1 1.4 8.8 0.0 4.5 3 2 2 5 5 5 1 Domain of unknown function (DUF3385) ATPgrasp_YheCD PF14398.6 EKX50352.1 - 0.0034 16.7 0.0 0.0081 15.4 0.0 1.5 1 0 0 1 1 1 1 YheC/D like ATP-grasp MMS19_C PF12460.8 EKX50352.1 - 0.0086 15.2 2.3 4.9 6.2 0.4 3.8 3 2 0 3 3 3 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 EKX50352.1 - 0.014 14.9 0.0 7 6.1 0.0 3.6 2 1 1 3 3 3 0 CLASP N terminal RTP1_C1 PF10363.9 EKX50352.1 - 0.03 14.5 0.0 3.9 7.7 0.0 3.4 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DNA_alkylation PF08713.11 EKX50352.1 - 0.095 12.4 0.0 0.91 9.2 0.0 2.6 3 1 1 4 4 4 0 DNA alkylation repair enzyme Thioredoxin_8 PF13905.6 EKX50353.1 - 2.2e-28 98.4 0.0 3.1e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EKX50353.1 - 9.5e-09 35.2 0.0 1.4e-08 34.7 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 EKX50353.1 - 1.1e-08 35.0 0.0 1.2e-06 28.4 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin Redoxin PF08534.10 EKX50353.1 - 1.8e-06 27.7 0.0 2.5e-06 27.3 0.0 1.3 1 1 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 EKX50353.1 - 0.0019 18.3 0.1 0.0057 16.8 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EKX50353.1 - 0.0031 17.9 0.0 0.0053 17.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EKX50353.1 - 0.041 13.7 0.0 0.12 12.2 0.0 1.7 1 1 1 2 2 2 0 Thioredoxin SCO1-SenC PF02630.14 EKX50353.1 - 0.047 13.6 0.0 0.072 13.0 0.0 1.2 1 0 0 1 1 1 0 SCO1/SenC TraF PF13728.6 EKX50353.1 - 0.05 13.4 0.0 0.36 10.6 0.0 1.9 1 1 0 1 1 1 0 F plasmid transfer operon protein Glutaredoxin PF00462.24 EKX50353.1 - 0.1 12.8 0.2 0.37 11.1 0.2 1.8 1 1 0 1 1 1 0 Glutaredoxin HEAT_2 PF13646.6 EKX50354.1 - 8.4e-05 22.9 7.1 0.025 15.0 0.2 3.3 2 1 2 4 4 4 2 HEAT repeats HEAT PF02985.22 EKX50354.1 - 0.0078 16.4 6.7 0.77 10.2 0.4 4.1 3 0 0 3 3 3 2 HEAT repeat DUF1295 PF06966.12 EKX50355.1 - 1.5e-34 119.6 1.2 1.8e-34 119.3 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) MrpF_PhaF PF04066.13 EKX50355.1 - 0.068 13.6 1.5 0.068 13.6 1.5 2.9 3 0 0 3 3 3 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) DUF2070 PF09843.9 EKX50355.1 - 7 4.8 6.3 9.2 4.4 6.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Mnd1 PF03962.15 EKX50357.1 - 7.8e-22 77.3 0.2 7.8e-22 77.3 0.2 1.9 2 0 0 2 2 2 1 Mnd1 HTH domain Exonuc_VII_L PF02601.15 EKX50357.1 - 0.012 15.2 2.7 0.015 14.9 2.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 EKX50357.1 - 0.015 14.4 4.0 0.017 14.2 4.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FapA PF03961.13 EKX50357.1 - 0.04 12.5 6.6 0.06 11.9 6.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Sec34 PF04136.15 EKX50357.1 - 0.042 13.7 7.4 0.024 14.5 5.1 1.7 2 0 0 2 2 2 0 Sec34-like family DUF3135 PF11333.8 EKX50357.1 - 0.048 13.9 0.5 1.9 8.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) AAA_11 PF13086.6 EKX50357.1 - 0.07 12.9 3.8 0.091 12.5 3.8 1.1 1 0 0 1 1 1 0 AAA domain Tho2 PF11262.8 EKX50357.1 - 0.11 11.7 5.0 0.17 11.1 5.0 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 LZ3wCH PF18517.1 EKX50357.1 - 0.17 12.0 0.2 0.17 12.0 0.2 2.6 3 0 0 3 3 3 0 Leucine zipper with capping helix domain COG2 PF06148.11 EKX50357.1 - 0.55 10.3 7.5 27 4.9 0.0 3.0 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TMPIT PF07851.13 EKX50357.1 - 5.2 6.2 5.6 7.4 5.7 5.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein Seryl_tRNA_N PF02403.22 EKX50357.1 - 6.9 6.9 15.1 4.5 7.5 11.6 2.3 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain PEP_mutase PF13714.6 EKX50358.1 - 6.2e-49 166.6 0.1 7.2e-49 166.4 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EKX50358.1 - 7.7e-12 44.5 0.3 1.1e-11 44.0 0.3 1.1 1 0 0 1 1 1 1 Isocitrate lyase family PEP_hydrolase PF09370.10 EKX50358.1 - 0.012 14.8 0.6 0.024 13.8 0.1 1.7 2 0 0 2 2 2 0 Phosphoenolpyruvate hydrolase-like Pantoate_transf PF02548.15 EKX50358.1 - 0.029 13.8 0.1 0.65 9.3 0.0 2.4 1 1 2 3 3 3 0 Ketopantoate hydroxymethyltransferase FKBP_C PF00254.28 EKX50359.1 - 4.5e-11 42.9 0.0 7.9e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase LNS2 PF08235.13 EKX50360.1 - 2.5e-24 86.0 0.0 3.5e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EKX50360.1 - 7.1e-11 42.0 0.2 1.7e-10 40.7 0.0 1.7 2 0 0 2 2 2 1 lipin, N-terminal conserved region Sin_N PF04801.13 EKX50360.1 - 0.45 9.7 2.7 0.61 9.2 2.7 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region LRR_8 PF13855.6 EKX50361.1 - 1.8e-46 155.7 29.3 1.7e-11 43.7 1.6 6.0 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 EKX50361.1 - 6.3e-24 83.7 33.9 2.3e-06 27.9 1.1 6.6 1 1 5 7 7 7 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX50361.1 - 1e-16 61.0 0.0 2.6e-08 33.9 0.0 2.6 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EKX50361.1 - 1.9e-09 36.7 23.6 2.3 9.1 0.0 9.5 9 1 0 9 9 9 4 Leucine Rich Repeat LRR_9 PF14580.6 EKX50361.1 - 1.3e-05 24.7 5.5 0.044 13.3 1.4 3.6 1 1 3 4 4 4 4 Leucine-rich repeat ING PF12998.7 EKX50361.1 - 0.11 13.1 0.5 6 7.5 0.1 3.3 4 1 1 5 5 5 0 Inhibitor of growth proteins N-terminal histone-binding PhoLip_ATPase_N PF16209.5 EKX50361.1 - 1.1 8.9 6.4 1.9 8.2 0.2 3.7 5 0 0 5 5 5 0 Phospholipid-translocating ATPase N-terminal Ephrin_rec_like PF07699.13 EKX50362.1 - 9.8e-27 92.5 157.0 6.9e-05 22.5 3.6 7.3 1 1 11 12 12 12 12 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX50362.1 - 1.3 9.5 40.5 21 5.6 0.8 8.7 1 1 9 10 10 10 0 TNFR/NGFR cysteine-rich region Pkinase_Tyr PF07714.17 EKX50363.1 - 3e-57 193.9 0.0 3.5e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX50363.1 - 5e-34 117.9 0.0 6.3e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain zf-C3HC4_3 PF13920.6 EKX50363.1 - 9.8e-12 44.6 9.7 1.8e-11 43.7 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX50363.1 - 3e-05 23.8 10.8 5.7e-05 22.9 10.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EKX50363.1 - 0.00017 21.8 11.2 0.00043 20.5 11.2 1.7 1 0 0 1 1 1 1 Ring finger domain RIO1 PF01163.22 EKX50363.1 - 0.0074 15.9 0.6 0.013 15.1 0.1 1.6 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 EKX50363.1 - 0.02 14.3 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_5 PF14634.6 EKX50363.1 - 0.033 14.2 10.5 0.096 12.7 10.5 1.8 1 0 0 1 1 1 0 zinc-RING finger domain DUF2723 PF11028.8 EKX50366.1 - 5.7e-28 98.0 1.4 1.4e-27 96.7 1.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2723) PMT_2 PF13231.6 EKX50366.1 - 3.6e-05 24.0 3.8 3.6e-05 24.0 3.8 2.4 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF4448 PF14610.6 EKX50366.1 - 0.054 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF2079 PF09852.9 EKX50366.1 - 0.78 8.5 12.5 0.13 11.0 1.5 2.7 2 1 1 3 3 3 0 Predicted membrane protein (DUF2079) Sel1 PF08238.12 EKX50367.1 - 2.4e-43 145.6 40.4 2.4e-07 31.2 0.1 10.1 9 1 0 9 9 9 9 Sel1 repeat TPR_1 PF00515.28 EKX50368.1 - 1e-28 97.9 1.0 3.3e-05 23.5 0.0 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 EKX50368.1 - 4.2e-28 96.7 11.0 3.9e-08 32.8 1.8 5.9 3 3 3 6 6 6 5 TPR repeat TPR_16 PF13432.6 EKX50368.1 - 6.9e-23 81.0 8.9 1.9e-05 25.2 0.1 4.5 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 EKX50368.1 - 9.2e-20 69.1 8.0 0.0033 17.4 0.3 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 EKX50368.1 - 4.8e-17 60.7 1.9 0.058 13.6 0.0 6.1 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 EKX50368.1 - 2.5e-16 58.8 5.0 0.074 13.5 0.0 6.1 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 EKX50368.1 - 1.1e-12 47.7 3.5 0.00024 21.6 0.6 4.7 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 EKX50368.1 - 1.6e-12 47.4 4.5 0.0015 18.7 0.4 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX50368.1 - 3.9e-11 43.1 8.5 0.0016 18.7 0.1 4.7 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_19 PF14559.6 EKX50368.1 - 1.2e-10 41.7 5.4 0.0053 17.2 0.1 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX50368.1 - 5e-06 26.8 12.4 0.56 11.0 0.1 6.1 6 1 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX50368.1 - 6.5e-05 23.1 2.9 0.91 9.8 0.0 3.2 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 EKX50368.1 - 0.0012 19.1 3.0 8.8 6.7 0.0 3.7 1 1 4 5 5 5 2 Tetratricopeptide repeat TOM20_plant PF06552.12 EKX50368.1 - 0.0034 17.2 0.1 2.4 7.9 0.1 3.0 2 1 1 3 3 3 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_7 PF13176.6 EKX50368.1 - 0.0079 16.2 2.1 20 5.5 0.0 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX50368.1 - 0.015 15.2 7.5 3 7.9 0.4 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.17 EKX50368.1 - 0.028 14.8 3.3 0.41 11.1 1.3 2.8 2 1 0 2 2 2 0 Bacterial transcriptional activator domain DnaJ PF00226.31 EKX50369.1 - 3.2e-16 59.2 0.5 3.8e-16 58.9 0.5 1.1 1 0 0 1 1 1 1 DnaJ domain Cupin_8 PF13621.6 EKX50370.1 - 4e-23 82.4 0.0 8.3e-23 81.4 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 EKX50370.1 - 0.038 13.7 0.0 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 Cupin domain JmjC PF02373.22 EKX50370.1 - 0.083 13.3 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 JmjC domain, hydroxylase LRR_4 PF12799.7 EKX50372.1 - 0.0016 18.8 0.1 0.03 14.7 0.2 2.3 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX50372.1 - 0.0031 17.3 0.0 0.008 15.9 0.0 1.7 1 1 0 1 1 1 1 Leucine rich repeat Pkinase_Tyr PF07714.17 EKX50373.1 - 5.2e-41 140.6 0.0 5.9e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX50373.1 - 2.1e-36 125.7 0.0 2.5e-36 125.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EKX50373.1 - 0.049 13.5 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3727 PF12527.8 EKX50375.1 - 2.2e-13 50.2 0.4 8.8e-11 41.9 0.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3727) DUF1292 PF06949.11 EKX50375.1 - 1.1e-07 32.6 0.8 0.0011 19.8 0.0 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF1292) CitMHS PF03600.16 EKX50376.1 - 0.031 13.5 0.4 0.078 12.2 0.5 1.4 1 1 0 1 1 1 0 Citrate transporter MSL2-CXC PF16682.5 EKX50378.1 - 0.00047 20.2 31.7 8.4 6.6 0.3 10.2 3 1 9 12 12 12 8 CXC domain of E3 ubiquitin-protein ligase MSL2 POR_N PF01855.19 EKX50378.1 - 2.2 7.9 4.1 19 4.9 0.1 3.5 2 1 2 5 5 5 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg CK2S PF15011.6 EKX50379.1 - 0.055 13.3 0.0 0.063 13.2 0.0 1.1 1 0 0 1 1 1 0 Casein Kinase 2 substrate RVT_1 PF00078.27 EKX50380.1 - 1.8e-08 34.2 0.1 3.5e-08 33.3 0.1 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Adaptin_N PF01602.20 EKX50381.1 - 2.8e-79 267.1 4.4 4.5e-79 266.4 4.4 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EKX50381.1 - 6.5e-44 149.8 2.7 5.9e-43 146.7 0.4 3.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 EKX50381.1 - 1.7e-15 57.1 0.0 5.2e-15 55.5 0.0 1.9 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT PF02985.22 EKX50381.1 - 4.3e-11 42.1 3.4 0.027 14.7 0.0 6.0 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 EKX50381.1 - 1.5e-08 34.9 6.2 0.00023 21.5 0.0 6.0 4 1 2 6 6 6 3 HEAT repeats Vac14_Fab1_bd PF12755.7 EKX50381.1 - 0.0023 18.5 0.2 0.062 13.9 0.1 2.9 2 1 1 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EKX50381.1 - 0.0036 17.8 8.9 36 5.0 0.0 6.3 4 2 2 6 6 6 0 HEAT-like repeat Arm_2 PF04826.13 EKX50381.1 - 0.016 14.7 4.6 0.2 11.1 2.4 3.0 1 1 1 2 2 2 0 Armadillo-like CLASP_N PF12348.8 EKX50381.1 - 0.04 13.5 0.0 0.79 9.2 0.1 3.1 2 1 0 2 2 2 0 CLASP N terminal Cohesin_HEAT PF12765.7 EKX50381.1 - 0.069 13.5 0.6 33 4.9 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion RPN7 PF10602.9 EKX50382.1 - 6.8e-43 146.4 3.5 1.1e-42 145.7 3.5 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EKX50382.1 - 4e-11 43.4 0.0 7.6e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 PCI domain ATG16 PF08614.11 EKX50383.1 - 0.0032 17.7 8.5 0.0044 17.3 8.5 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4715 PF15835.5 EKX50383.1 - 0.041 14.0 7.7 0.068 13.2 6.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4715) MscS_porin PF12795.7 EKX50383.1 - 0.056 13.0 11.7 0.11 12.0 0.8 2.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF4407 PF14362.6 EKX50383.1 - 0.31 10.3 6.9 0.48 9.7 6.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 EKX50383.1 - 0.36 11.3 6.4 1.3 9.6 6.3 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein TMPIT PF07851.13 EKX50383.1 - 3.6 6.7 6.6 4.9 6.3 6.6 1.3 1 0 0 1 1 1 0 TMPIT-like protein Cnd1 PF12717.7 EKX50387.1 - 0.41 10.7 4.1 0.46 10.5 0.1 3.2 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 EKX50387.1 - 0.95 9.4 4.1 3.5 7.5 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) Bac_rhodopsin PF01036.18 EKX50388.1 - 5.2e-40 137.4 21.2 6.9e-40 137.0 21.2 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Kelch_6 PF13964.6 EKX50388.1 - 0.12 12.7 0.2 0.55 10.6 0.0 2.0 2 0 0 2 2 2 0 Kelch motif GWT1 PF06423.12 EKX50388.1 - 7 6.8 9.4 0.35 11.0 3.7 1.8 2 1 0 2 2 2 0 GWT1 SET PF00856.28 EKX50389.1 - 0.044 14.2 1.1 0.061 13.7 1.1 1.2 1 0 0 1 1 1 0 SET domain Strabismus PF06638.11 EKX50389.1 - 0.18 10.4 6.7 0.24 10.0 6.7 1.3 1 0 0 1 1 1 0 Strabismus protein DUF1682 PF07946.14 EKX50389.1 - 1 8.5 13.2 1.4 8.0 13.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF4230 PF14014.6 EKX50389.1 - 6.6 7.0 12.4 1.2 9.4 7.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4230) EF-hand_1 PF00036.32 EKX50390.1 - 1.3e-09 36.9 2.5 4e-06 26.0 0.1 2.9 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EKX50390.1 - 7.9e-09 35.2 0.3 1.6e-08 34.2 0.3 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 EKX50390.1 - 1.3e-08 35.2 0.9 6.7e-08 32.9 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX50390.1 - 4e-05 23.2 0.3 0.12 12.4 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 EKX50390.1 - 0.00044 19.6 7.1 0.0072 15.8 0.1 3.1 3 0 0 3 3 3 2 EF hand FTCD_N PF07837.12 EKX50391.1 - 4.9e-40 137.2 0.7 5.6e-38 130.5 0.5 3.0 2 1 0 2 2 2 1 Formiminotransferase domain, N-terminal subdomain DUF3140 PF11338.8 EKX50391.1 - 0.22 12.0 0.9 1.1 9.8 0.3 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3140) Apolipoprotein PF01442.18 EKX50392.1 - 3.6e-10 40.0 112.6 0.00044 20.2 21.1 7.9 2 1 3 5 5 5 2 Apolipoprotein A1/A4/E domain Myosin_tail_1 PF01576.19 EKX50392.1 - 3.9e-05 21.7 135.5 5.5e-05 21.2 42.8 4.1 1 1 1 3 3 3 2 Myosin tail Baculo_PEP_C PF04513.12 EKX50392.1 - 4e-05 23.7 31.7 0.71 9.9 0.0 8.7 4 2 7 11 11 11 5 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 EKX50392.1 - 0.00069 19.7 74.9 0.11 12.5 5.8 10.4 2 2 8 11 11 11 6 Protein of unknown function (DUF1664) Spc7 PF08317.11 EKX50392.1 - 0.0014 17.6 8.5 0.0014 17.6 8.5 7.1 1 1 6 7 7 7 3 Spc7 kinetochore protein DUF3584 PF12128.8 EKX50392.1 - 0.012 13.2 107.5 0.0052 14.4 33.1 4.5 1 1 4 5 5 5 0 Protein of unknown function (DUF3584) DUF5633 PF18656.1 EKX50392.1 - 2.6 8.0 6.5 5.4 7.0 1.1 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5633) DUF4407 PF14362.6 EKX50392.1 - 5.9 6.2 76.5 0.15 11.3 14.1 5.3 2 1 3 5 5 5 0 Domain of unknown function (DUF4407) ApoO PF09769.9 EKX50392.1 - 8 6.4 18.1 33 4.4 0.3 6.9 3 3 5 8 8 8 0 Apolipoprotein O CHB_HEX_C_1 PF13290.6 EKX50393.1 - 2.6e-18 65.8 0.0 3.1e-09 36.7 0.0 3.9 3 0 0 3 3 3 2 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 EKX50393.1 - 1.1e-12 47.8 0.0 2.4e-06 27.6 0.0 3.1 2 0 0 2 2 2 2 Fn3 associated Ricin_B_lectin PF00652.22 EKX50393.1 - 0.00044 20.5 3.5 0.00045 20.5 1.4 2.0 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain PAN_4 PF14295.6 EKX50393.1 - 0.00078 19.3 4.3 0.00078 19.3 4.3 3.2 3 0 0 3 3 3 1 PAN domain PPC PF04151.15 EKX50393.1 - 0.13 13.4 12.8 0.42 11.7 0.4 5.0 4 0 0 4 4 4 0 Bacterial pre-peptidase C-terminal domain PAN_1 PF00024.26 EKX50393.1 - 6 6.9 11.6 0.41 10.6 4.6 2.6 1 1 1 2 2 2 0 PAN domain Glyco_trans_1_2 PF13524.6 EKX50395.1 - 0.011 16.0 0.0 0.45 10.9 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferases group 1 DUF4571 PF15137.6 EKX50395.1 - 0.032 13.9 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4571) Bmt2 PF11968.8 EKX50396.1 - 8.5e-24 84.6 0.5 2.2e-23 83.3 0.5 1.7 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 HTH_22 PF13309.6 EKX50396.1 - 0.86 9.7 3.3 13 5.9 0.1 2.8 2 0 0 2 2 2 0 HTH domain IL3 PF02059.15 EKX50397.1 - 0.14 12.2 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 Interleukin-3 FA_desaturase PF00487.24 EKX50398.1 - 0.024 14.5 4.6 0.03 14.2 4.6 1.2 1 0 0 1 1 1 0 Fatty acid desaturase TetR_C_24 PF17932.1 EKX50399.1 - 0.12 12.6 3.1 0.19 12.0 3.1 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Pex26 PF07163.12 EKX50399.1 - 0.2 11.0 1.5 0.31 10.3 1.5 1.4 1 0 0 1 1 1 0 Pex26 protein Aldedh PF00171.22 EKX50399.1 - 5.5 5.4 5.3 29 3.0 5.3 1.9 1 1 0 1 1 1 0 Aldehyde dehydrogenase family FapA PF03961.13 EKX50399.1 - 7.3 5.1 9.5 9.5 4.7 9.5 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Sel1 PF08238.12 EKX50400.1 - 3.9e-09 36.9 2.5 0.039 14.6 0.0 6.4 6 0 0 6 6 6 3 Sel1 repeat Questin_oxidase PF14027.6 EKX50400.1 - 0.032 13.8 0.0 0.078 12.5 0.0 1.6 2 0 0 2 2 2 0 Questin oxidase-like Adeno_E3A PF05248.12 EKX50401.1 - 0.14 12.2 0.0 0.69 10.0 0.0 2.1 2 0 0 2 2 2 0 Adenovirus E3A NUDIX PF00293.28 EKX50402.1 - 3.9e-16 59.3 0.0 7.6e-16 58.4 0.0 1.4 2 0 0 2 2 2 1 NUDIX domain FSH1 PF03959.13 EKX50403.1 - 6.1e-14 52.2 0.0 8.1e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) LSM PF01423.22 EKX50404.1 - 6e-21 73.9 0.0 7e-21 73.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 EKX50404.1 - 0.0015 18.6 0.1 0.0021 18.1 0.1 1.2 1 0 0 1 1 1 1 RimP C-terminal SH3 domain Arf PF00025.21 EKX50405.1 - 5.7e-58 195.2 0.0 6.4e-58 195.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EKX50405.1 - 9.4e-11 41.5 0.1 5e-07 29.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EKX50405.1 - 1.3e-08 35.0 0.0 3.4e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EKX50405.1 - 1.8e-08 34.2 0.0 2.1e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EKX50405.1 - 1.9e-08 33.9 0.0 2.3e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EKX50405.1 - 5.8e-08 32.4 0.0 7.2e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EKX50405.1 - 1.4e-06 28.4 0.0 1.9e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EKX50405.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 EKX50405.1 - 0.19 11.3 0.1 11 5.5 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Cmc1 PF08583.10 EKX50406.1 - 0.0094 16.0 0.8 0.035 14.1 0.8 2.0 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like MSP7_C PF12948.7 EKX50406.1 - 0.024 15.3 1.2 0.052 14.2 0.1 2.1 2 0 0 2 2 2 0 MSP7-like protein C-terminal domain EP400_N PF15790.5 EKX50406.1 - 0.034 13.0 0.1 0.052 12.4 0.1 1.2 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal HAUS-augmin3 PF14932.6 EKX50406.1 - 0.3 10.6 20.2 0.082 12.5 0.5 3.1 2 2 0 3 3 3 0 HAUS augmin-like complex subunit 3 SATase_N PF06426.14 EKX50406.1 - 5.2 7.5 5.8 1.1 9.7 0.2 2.6 3 1 0 3 3 3 0 Serine acetyltransferase, N-terminal DivIC PF04977.15 EKX50406.1 - 5.5 6.8 6.4 8.7 6.2 0.3 3.4 3 0 0 3 3 3 0 Septum formation initiator DCB PF16213.5 EKX50407.1 - 4.8e-24 85.0 0.3 7.6e-23 81.1 0.0 2.7 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 EKX50407.1 - 5e-23 81.2 9.2 1.8e-12 46.3 0.0 4.4 3 1 1 4 4 4 4 C-terminal region of Mon2 protein Sec7_N PF12783.7 EKX50407.1 - 5.3e-14 52.4 0.1 5.3e-14 52.4 0.1 3.6 5 0 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EKX50407.1 - 9.3e-07 28.6 0.0 1.2e-05 25.0 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) UQ_con PF00179.26 EKX50408.1 - 1.3e-22 80.0 0.0 1.6e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EKX50408.1 - 0.00049 19.9 0.0 0.00076 19.3 0.0 1.3 1 0 0 1 1 1 1 UEV domain MORN PF02493.20 EKX50410.1 - 7.9e-27 91.5 50.1 8.9e-07 28.4 0.6 8.3 8 0 0 8 8 8 8 MORN repeat RINGv PF12906.7 EKX50411.1 - 3.2e-13 49.6 5.0 7.5e-13 48.4 5.0 1.7 1 1 0 1 1 1 1 RING-variant domain DUF179 PF02622.15 EKX50411.1 - 3.5e-05 23.8 0.0 5.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 FANCL_C PF11793.8 EKX50411.1 - 0.0014 18.7 2.0 0.0036 17.4 2.0 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain Glyco_hydro_75 PF07335.11 EKX50411.1 - 0.037 14.3 0.0 0.074 13.3 0.0 1.5 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 zf-AD PF07776.15 EKX50411.1 - 0.2 11.9 5.3 0.48 10.7 5.3 1.7 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) zf-RING_2 PF13639.6 EKX50411.1 - 2.2 8.7 11.0 6.7 7.1 9.9 2.2 1 1 1 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.6 EKX50411.1 - 3.6 7.5 9.1 3.4 7.6 2.0 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) NDK PF00334.19 EKX50412.1 - 1.8e-08 34.5 0.0 0.00027 21.0 0.0 2.4 2 0 0 2 2 2 2 Nucleoside diphosphate kinase Cpn60_TCP1 PF00118.24 EKX50413.1 - 4.9e-154 513.6 13.6 5.6e-154 513.4 13.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SCAB_CC PF16712.5 EKX50413.1 - 0.047 13.5 0.3 0.13 12.1 0.3 1.7 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein Ank_5 PF13857.6 EKX50414.1 - 5.1e-11 42.6 0.1 3e-07 30.6 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX50414.1 - 1.1e-08 35.6 0.0 1.1e-08 35.5 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX50414.1 - 7.2e-08 32.1 0.0 0.024 15.2 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EKX50414.1 - 7.5e-08 32.5 0.0 0.0028 18.0 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EKX50414.1 - 5.1e-07 30.1 0.0 3.2e-05 24.4 0.1 2.7 1 1 2 3 3 3 1 Ankyrin repeats (many copies) TPR_11 PF13414.6 EKX50415.1 - 1.1e-07 31.5 0.1 0.062 13.0 0.0 4.1 3 0 0 3 3 3 2 TPR repeat TPR_14 PF13428.6 EKX50415.1 - 4.1e-07 30.3 1.5 1.8 9.6 0.0 7.7 6 3 2 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX50415.1 - 0.0002 21.5 0.0 0.0031 17.8 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX50415.1 - 0.00024 21.0 2.1 7.1 7.0 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat Vps39_1 PF10366.9 EKX50415.1 - 0.0055 17.0 0.7 0.0055 17.0 0.7 2.7 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 TPR_6 PF13174.6 EKX50415.1 - 0.0059 17.2 2.2 16 6.4 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX50415.1 - 0.11 12.7 2.0 8.1 6.8 0.1 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EKX50415.1 - 0.11 13.0 2.9 34 5.0 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX50415.1 - 0.22 11.8 0.0 0.22 11.8 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat RNA_pol_Rpb1_7 PF04990.12 EKX50415.1 - 0.57 10.2 2.1 0.99 9.4 0.3 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 7 TPR_12 PF13424.6 EKX50415.1 - 7.3 7.0 8.8 2.8 8.3 0.0 4.5 6 1 0 7 7 6 0 Tetratricopeptide repeat Pkinase PF00069.25 EKX50416.1 - 3.4e-71 239.7 0.0 3.8e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX50416.1 - 5.4e-35 120.9 0.1 1.1e-34 119.9 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EKX50416.1 - 0.0022 17.7 0.1 0.0032 17.1 0.1 1.1 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 EKX50416.1 - 0.026 13.3 0.0 0.097 11.4 0.0 1.7 1 1 1 2 2 2 0 Fungal protein kinase Avl9 PF09794.9 EKX50418.1 - 0.00045 19.0 0.6 0.00078 18.2 0.2 1.5 1 1 0 1 1 1 1 Transport protein Avl9 Aldo_ket_red PF00248.21 EKX50419.1 - 2.1e-57 194.6 0.0 2.3e-57 194.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_Tnp_ISL3 PF13542.6 EKX50420.1 - 0.059 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Zn_clus PF00172.18 EKX50421.1 - 0.0014 18.7 9.8 0.0014 18.7 9.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydrolase_6 PF13344.6 EKX50422.1 - 5.5e-18 64.9 0.0 7.9e-17 61.2 0.0 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EKX50422.1 - 3.1e-10 40.0 0.0 6.7e-10 38.9 0.0 1.7 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EKX50422.1 - 3.6e-10 40.5 0.0 1.4e-05 25.5 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EKX50422.1 - 9e-09 35.7 0.0 0.00037 20.6 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase DnaJ PF00226.31 EKX50424.1 - 1.3e-18 66.8 0.0 1.4e-18 66.8 0.0 1.0 1 0 0 1 1 1 1 DnaJ domain Ank_5 PF13857.6 EKX50425.1 - 1.5e-14 53.9 0.2 1.9e-07 31.2 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX50425.1 - 7e-14 52.0 0.1 6.2e-08 33.0 0.0 2.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX50425.1 - 2.9e-13 50.2 0.0 4.8e-13 49.5 0.0 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX50425.1 - 8e-12 45.1 0.1 0.0013 19.1 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EKX50425.1 - 1.4e-10 40.4 0.2 0.0054 17.1 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat pRN1_helical PF13010.6 EKX50425.1 - 0.14 12.1 0.0 9.9 6.1 0.0 1.9 1 1 1 2 2 2 0 Primase helical domain VWA_2 PF13519.6 EKX50426.1 - 1.9e-10 41.3 0.0 4.2e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Zn_Tnp_IS1595 PF12760.7 EKX50426.1 - 0.068 13.2 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain VWA PF00092.28 EKX50426.1 - 0.075 13.3 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain TFIIB PF00382.19 EKX50427.1 - 5.4e-07 29.6 2.9 7e-07 29.2 1.0 2.2 2 1 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_N PF00134.23 EKX50427.1 - 0.0088 15.8 0.2 0.015 15.0 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain HD_4 PF13328.6 EKX50427.1 - 0.034 13.9 0.6 0.09 12.5 0.1 1.8 2 0 0 2 2 2 0 HD domain SBD PF17882.1 EKX50428.1 - 0.01 15.7 0.3 0.059 13.2 0.0 2.2 3 0 0 3 3 3 0 OAA-family lectin sugar binding domain TPR_14 PF13428.6 EKX50429.1 - 8.9e-16 57.3 10.2 0.1 13.5 1.1 9.3 5 3 5 10 10 9 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX50429.1 - 6.1e-11 41.6 10.4 0.12 12.6 0.2 7.0 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EKX50429.1 - 3.1e-10 39.7 13.0 0.023 15.1 0.1 7.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX50429.1 - 8.1e-10 39.1 5.6 0.0023 18.4 0.3 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX50429.1 - 1.4e-09 38.5 9.1 0.00019 22.0 2.4 4.9 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX50429.1 - 2.1e-06 27.5 9.4 0.26 11.6 0.1 6.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX50429.1 - 1.4e-05 25.1 4.8 0.013 15.6 0.9 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX50429.1 - 0.00016 21.3 8.1 19 5.3 0.1 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_11 PF13414.6 EKX50429.1 - 0.00019 21.0 15.1 0.14 11.9 0.1 7.1 8 0 0 8 8 8 2 TPR repeat ANAPC3 PF12895.7 EKX50429.1 - 0.00065 19.9 7.8 0.0026 17.9 0.3 3.5 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EKX50429.1 - 0.0014 18.9 12.0 4.7 7.6 0.2 5.4 4 2 0 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX50429.1 - 0.0025 17.9 8.8 2.6 8.2 0.0 5.9 4 1 2 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 EKX50429.1 - 0.0041 17.0 4.5 5.1 7.4 0.0 5.7 7 0 0 7 7 7 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EKX50429.1 - 0.021 14.5 0.2 0.14 11.8 0.0 2.4 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_6 PF13174.6 EKX50429.1 - 0.088 13.5 7.8 6 7.7 0.1 4.9 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 EKX50429.1 - 0.12 11.6 6.9 0.26 10.4 0.4 3.4 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 EKX50429.1 - 0.14 12.5 0.8 25 5.3 0.1 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 EKX50430.1 - 5.1e-46 157.2 0.0 6.2e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX50430.1 - 1.7e-15 57.1 0.0 2.2e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PDZ_6 PF17820.1 EKX50431.1 - 2e-06 27.6 0.0 5.5e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX50431.1 - 1.8e-05 24.9 0.0 3.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX50431.1 - 0.00034 20.9 0.0 0.00054 20.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX50431.1 - 0.055 13.4 0.0 0.15 12.1 0.0 1.7 1 1 0 1 1 1 0 Tricorn protease PDZ domain TANGO2 PF05742.12 EKX50432.1 - 1.3e-30 107.3 0.0 2.2e-30 106.5 0.0 1.3 1 1 0 1 1 1 1 Transport and Golgi organisation 2 PAP_fibrillin PF04755.12 EKX50434.1 - 3.1e-06 27.3 0.0 5.5e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 PAP_fibrillin RabGAP-TBC PF00566.18 EKX50435.1 - 1.1e-52 178.8 4.4 1.3e-52 178.6 4.4 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TipAS PF07739.13 EKX50435.1 - 0.04 14.5 0.1 0.094 13.3 0.1 1.7 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Methyltr_RsmB-F PF01189.17 EKX50438.1 - 7.4e-33 113.9 0.0 3.2e-32 111.8 0.0 1.9 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EKX50438.1 - 2.2e-06 27.9 0.0 8.5e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 EKX50438.1 - 0.00022 21.1 0.0 0.012 15.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX50438.1 - 0.0049 17.5 0.0 0.18 12.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX50438.1 - 0.0092 15.3 0.0 0.053 12.8 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EKX50438.1 - 0.038 13.7 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PUA PF01472.20 EKX50438.1 - 0.13 12.3 0.0 3.5 7.7 0.0 2.3 1 1 0 1 1 1 0 PUA domain Fibrillarin PF01269.17 EKX50438.1 - 0.21 10.6 0.0 0.36 9.9 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin RYDR_ITPR PF01365.21 EKX50439.1 - 4.5e-29 101.3 5.2 8.4e-17 61.3 0.2 3.1 3 0 0 3 3 3 2 RIH domain RIH_assoc PF08454.11 EKX50439.1 - 7.2e-11 41.8 0.1 7.2e-11 41.8 0.1 4.2 5 0 0 5 5 5 1 RyR and IP3R Homology associated Ins145_P3_rec PF08709.11 EKX50439.1 - 3.9e-09 36.0 0.1 2.4e-08 33.4 0.0 2.1 2 0 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 EKX50439.1 - 6e-07 29.5 0.1 1.8e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 MIR domain Ion_trans PF00520.31 EKX50439.1 - 3.2e-05 23.3 14.5 6.6e-05 22.2 14.5 1.5 1 0 0 1 1 1 1 Ion transport protein DUF3361 PF11841.8 EKX50439.1 - 0.15 12.0 2.0 2.1 8.3 0.0 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF3361) Methyltr_RsmB-F PF01189.17 EKX50441.1 - 4.1e-11 42.9 0.0 5.1e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F PUA PF01472.20 EKX50441.1 - 0.00011 22.1 0.1 0.0005 20.0 0.1 1.9 1 1 0 1 1 1 1 PUA domain ELMO_CED12 PF04727.13 EKX50442.1 - 9.7e-26 90.9 0.1 1.1e-25 90.8 0.1 1.0 1 0 0 1 1 1 1 ELMO/CED-12 family Yippee-Mis18 PF03226.14 EKX50445.1 - 2.6e-06 27.6 0.9 0.00019 21.6 0.0 2.5 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DiS_P_DiS PF06750.13 EKX50445.1 - 0.3 11.2 3.0 8.4 6.6 0.0 2.8 3 0 0 3 3 3 0 Bacterial Peptidase A24 N-terminal domain zf-ribbon_3 PF13248.6 EKX50445.1 - 0.85 9.1 9.4 0.33 10.4 1.8 2.5 2 0 0 2 2 2 0 zinc-ribbon domain NTP_transferase PF00483.23 EKX50446.1 - 7.1e-14 52.0 0.0 1.2e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EKX50446.1 - 2.5e-06 28.0 0.0 3.2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 EKX50446.1 - 7.5e-06 25.5 14.6 0.049 13.4 5.0 3.6 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 EKX50446.1 - 9.2e-05 21.6 7.8 0.00072 18.6 7.8 2.1 1 1 0 1 1 1 1 L-fucokinase Hexapep_2 PF14602.6 EKX50446.1 - 0.05 13.4 12.6 5.3 6.9 8.1 3.8 2 1 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 EKX50446.1 - 0.073 11.2 7.1 0.31 9.1 7.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) Glutaredoxin PF00462.24 EKX50447.1 - 4.2e-22 78.1 0.2 3.1e-21 75.3 0.0 2.1 2 1 0 2 2 2 1 Glutaredoxin GST_N_2 PF13409.6 EKX50447.1 - 0.00028 21.1 0.0 0.00034 20.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_3 PF13192.6 EKX50447.1 - 0.00036 20.5 0.0 0.00074 19.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin domain DSBA PF01323.20 EKX50447.1 - 0.00093 19.0 1.4 0.045 13.5 0.8 2.3 1 1 1 2 2 2 2 DSBA-like thioredoxin domain DUF836 PF05768.14 EKX50447.1 - 0.0012 19.2 0.0 0.002 18.5 0.0 1.5 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin PF00085.20 EKX50447.1 - 0.0029 17.6 0.1 0.0033 17.4 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EKX50447.1 - 0.003 18.0 0.3 0.0093 16.4 0.3 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain GST_N_3 PF13417.6 EKX50447.1 - 0.039 14.3 0.0 0.049 14.1 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain SH3BGR PF04908.15 EKX50447.1 - 0.041 14.1 0.0 0.048 13.8 0.0 1.2 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Thioredoxin_4 PF13462.6 EKX50447.1 - 0.06 13.5 0.7 4.1 7.5 0.5 2.1 1 1 1 2 2 2 0 Thioredoxin ABC1 PF03109.16 EKX50448.1 - 1.8e-32 112.0 0.1 3e-32 111.3 0.1 1.4 1 0 0 1 1 1 1 ABC1 family H_PPase PF03030.16 EKX50448.1 - 0.019 13.6 0.0 0.021 13.5 0.0 1.1 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase APH PF01636.23 EKX50448.1 - 0.024 14.6 0.2 0.078 12.9 0.2 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family NAD_binding_5 PF07994.12 EKX50448.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase RWP-RK PF02042.15 EKX50449.1 - 2.8e-14 52.8 0.0 5.3e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX50450.1 - 2e-14 53.3 0.0 3.5e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX50451.1 - 2.7e-14 52.8 0.0 4.9e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain FPP PF05911.11 EKX50452.1 - 7.6e-06 24.4 19.5 1.1e-05 23.9 19.5 1.2 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Lebercilin PF15619.6 EKX50452.1 - 0.00033 20.4 29.8 0.00033 20.4 29.8 2.4 1 1 1 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease AAA_13 PF13166.6 EKX50452.1 - 0.0013 17.5 17.1 0.002 16.9 17.1 1.2 1 0 0 1 1 1 1 AAA domain Tropomyosin PF00261.20 EKX50452.1 - 0.0056 16.1 31.8 0.008 15.6 6.3 2.3 1 1 1 2 2 2 1 Tropomyosin DUF4618 PF15397.6 EKX50452.1 - 0.007 15.8 8.2 0.007 15.8 8.2 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF4618) HrpB7 PF09486.10 EKX50452.1 - 0.022 15.2 19.8 0.043 14.2 9.5 2.9 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) Macoilin PF09726.9 EKX50452.1 - 0.023 13.3 19.3 0.03 12.9 19.3 1.1 1 0 0 1 1 1 0 Macoilin family NPAT_C PF15712.5 EKX50452.1 - 0.04 12.6 11.0 0.052 12.2 11.0 1.1 1 0 0 1 1 1 0 NPAT C terminus Spc7 PF08317.11 EKX50452.1 - 0.067 12.1 31.0 0.1 11.5 9.2 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4094 PF13334.6 EKX50452.1 - 0.086 13.3 0.5 0.086 13.3 0.5 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) KxDL PF10241.9 EKX50452.1 - 0.087 13.1 13.0 0.076 13.3 5.2 3.3 1 1 1 2 2 2 0 Uncharacterized conserved protein MscS_porin PF12795.7 EKX50452.1 - 0.11 12.0 22.6 0.17 11.4 19.8 2.1 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain HMMR_N PF15905.5 EKX50452.1 - 0.13 11.7 31.7 0.1 12.0 29.1 1.9 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF1664 PF07889.12 EKX50452.1 - 0.15 12.1 16.6 0.16 12.0 8.5 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) HemX PF04375.14 EKX50452.1 - 0.15 11.3 20.3 0.021 14.1 11.5 2.2 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase HOOK PF05622.12 EKX50452.1 - 0.18 9.9 30.7 0.033 12.4 11.3 2.2 1 1 1 2 2 2 0 HOOK protein TACC_C PF05010.14 EKX50452.1 - 0.41 10.4 27.1 0.039 13.7 19.8 2.3 3 0 0 3 3 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Rootletin PF15035.6 EKX50452.1 - 0.47 10.4 23.7 0.89 9.5 23.7 1.5 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Phage_HK97_TLTM PF06120.11 EKX50452.1 - 0.49 9.5 15.6 0.019 14.2 3.9 2.1 1 1 1 2 2 2 0 Tail length tape measure protein MAD PF05557.13 EKX50452.1 - 0.51 8.7 29.7 1.5 7.1 28.4 1.6 1 1 0 1 1 1 0 Mitotic checkpoint protein Tropomyosin_1 PF12718.7 EKX50452.1 - 0.58 10.3 36.6 4.9 7.3 36.5 2.2 1 1 0 1 1 1 0 Tropomyosin like DUF641 PF04859.12 EKX50452.1 - 0.67 10.3 20.6 5.9 7.2 9.9 2.8 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) GvpL_GvpF PF06386.11 EKX50452.1 - 0.74 9.7 18.3 11 5.8 17.2 2.2 1 1 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF DHR10 PF18595.1 EKX50452.1 - 0.84 9.7 36.7 0.69 10.0 20.9 3.0 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain XhlA PF10779.9 EKX50452.1 - 0.98 9.7 18.5 1.2 9.4 4.2 3.5 2 1 1 3 3 3 0 Haemolysin XhlA ATG16 PF08614.11 EKX50452.1 - 1.2 9.3 35.8 0.98 9.6 15.9 3.0 2 1 2 4 4 3 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 EKX50452.1 - 1.2 8.6 23.0 8.6 5.8 23.0 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit Uds1 PF15456.6 EKX50452.1 - 1.3 9.2 23.5 2.8 8.1 6.2 2.8 1 1 1 2 2 2 0 Up-regulated During Septation Laminin_II PF06009.12 EKX50452.1 - 1.4 9.0 16.8 0.091 12.8 8.8 2.7 2 1 2 4 4 3 0 Laminin Domain II GAS PF13851.6 EKX50452.1 - 1.8 7.9 30.3 7.8 5.8 28.3 2.6 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3552 PF12072.8 EKX50452.1 - 2.1 7.7 34.9 0.3 10.5 27.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) ADIP PF11559.8 EKX50452.1 - 2.2 8.4 34.4 1 9.4 0.6 3.9 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.9 EKX50452.1 - 2.3 7.2 29.7 1.4 7.9 23.7 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4446 PF14584.6 EKX50452.1 - 2.7 7.9 14.9 1.8 8.6 4.9 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) OmpH PF03938.14 EKX50452.1 - 2.9 8.2 27.8 13 6.1 6.8 3.0 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) IFT57 PF10498.9 EKX50452.1 - 2.9 6.8 23.6 1.6 7.6 9.1 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF4407 PF14362.6 EKX50452.1 - 3.1 7.1 17.9 10 5.4 17.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FUSC PF04632.12 EKX50452.1 - 3.4 6.1 11.3 8.9 4.7 9.2 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF16 PF01519.16 EKX50452.1 - 3.7 8.1 23.3 4.1 8.0 10.7 3.8 2 1 3 5 5 4 0 Protein of unknown function DUF16 FapA PF03961.13 EKX50452.1 - 4.5 5.8 18.6 1.9 7.0 15.5 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF3584 PF12128.8 EKX50452.1 - 4.7 4.6 31.1 0.37 8.2 18.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TMF_DNA_bd PF12329.8 EKX50452.1 - 5.2 7.1 25.7 12 6.0 1.3 3.5 2 2 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Prominin PF05478.11 EKX50452.1 - 9.4 4.0 14.3 1.6 6.6 10.8 1.4 2 0 0 2 2 2 0 Prominin DUF724 PF05266.14 EKX50452.1 - 9.5 6.0 30.0 12 5.7 18.2 2.9 2 1 1 3 3 2 0 Protein of unknown function (DUF724) DUF4215 PF13948.6 EKX50453.1 - 0.3 11.6 6.0 0.15 12.5 2.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4215) Fumble PF03630.14 EKX50454.1 - 3.2e-46 158.1 0.0 4.4e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Fumble Guanylate_cyc PF00211.20 EKX50455.1 - 2e-48 164.4 0.1 2.6e-48 164.1 0.1 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pterin_4a PF01329.19 EKX50457.1 - 2e-11 43.9 0.0 2.2e-11 43.8 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Pox_MCEL PF03291.16 EKX50458.1 - 6.5e-61 206.3 0.0 7.3e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 EKX50458.1 - 6.2e-14 52.5 0.0 1.5e-13 51.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX50458.1 - 3.6e-12 46.7 0.0 8e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX50458.1 - 4.8e-11 42.7 0.0 1.3e-10 41.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX50458.1 - 7.2e-11 42.7 0.0 5e-10 40.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX50458.1 - 2.7e-07 30.6 0.0 4.3e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX50458.1 - 0.00012 21.5 0.0 0.00024 20.5 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 EKX50458.1 - 0.0064 15.7 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.17 EKX50458.1 - 0.029 13.8 0.0 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Putative methyltransferase TPMT PF05724.11 EKX50458.1 - 0.054 13.2 0.0 0.074 12.7 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Lipase3_N PF03893.16 EKX50458.1 - 0.12 12.4 0.1 6.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Lipase 3 N-terminal region Glyco_transf_41 PF13844.6 EKX50460.1 - 2e-84 283.7 0.5 1.4e-41 142.5 0.2 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_8 PF13181.6 EKX50460.1 - 4e-17 60.9 0.0 0.0024 18.0 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX50460.1 - 3.4e-16 58.3 0.3 9.8e-05 22.0 0.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX50460.1 - 9.2e-16 56.6 0.2 0.0017 18.3 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX50460.1 - 5.2e-14 51.5 0.9 5.5e-05 23.3 0.0 5.3 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX50460.1 - 2.9e-12 46.7 1.4 3.5e-05 24.0 0.0 4.1 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX50460.1 - 2.4e-10 39.9 2.1 0.0049 16.7 0.0 4.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX50460.1 - 4.6e-10 40.0 0.5 3.3e-05 24.4 0.0 3.5 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 EKX50460.1 - 8.8e-10 38.1 0.1 0.00087 18.9 0.0 3.6 2 1 1 3 3 3 2 TPR repeat TPR_14 PF13428.6 EKX50460.1 - 2.5e-09 37.1 0.3 1.2 10.2 0.0 5.8 2 2 4 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX50460.1 - 2.2e-06 28.1 0.5 0.00051 20.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX50460.1 - 2.6e-06 27.1 0.2 0.034 14.2 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX50460.1 - 0.054 13.7 0.1 2.2 8.5 0.0 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 EKX50460.1 - 0.095 12.8 1.0 0.54 10.4 0.0 2.8 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain Phage_terminase PF10668.9 EKX50461.1 - 0.0015 18.5 0.6 0.0031 17.5 0.6 1.7 1 0 0 1 1 1 1 Phage terminase small subunit RrnaAD PF00398.20 EKX50463.1 - 2.7e-61 207.0 0.0 3.8e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EKX50463.1 - 2e-05 25.2 0.0 6.2e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX50463.1 - 0.0048 17.5 0.0 0.01 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX50463.1 - 0.011 16.4 0.0 0.027 15.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 EKX50463.1 - 0.016 14.7 0.2 0.038 13.5 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.14 EKX50463.1 - 0.018 14.6 0.2 0.044 13.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain DREV PF05219.12 EKX50463.1 - 0.02 14.0 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase NodS PF05401.11 EKX50463.1 - 0.02 14.5 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) FA_hydroxylase PF04116.13 EKX50464.1 - 4.9e-17 62.5 16.7 4.9e-17 62.5 16.7 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily COX4_pro PF03626.14 EKX50464.1 - 0.0021 18.4 0.2 0.012 16.0 0.0 2.4 3 0 0 3 3 3 1 Prokaryotic Cytochrome C oxidase subunit IV Spore_YabQ PF09578.10 EKX50464.1 - 0.12 12.6 3.1 1.7 8.9 0.0 2.6 2 0 0 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) QueT PF06177.11 EKX50464.1 - 0.25 11.7 2.2 1.6 9.1 0.1 2.6 3 0 0 3 3 3 0 QueT transporter L51_S25_CI-B8 PF05047.16 EKX50465.1 - 2.8e-08 33.6 0.0 4.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF3135 PF11333.8 EKX50466.1 - 0.18 12.0 10.8 2.8 8.2 1.1 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3135) Glycos_transf_1 PF00534.20 EKX50468.1 - 6.9e-16 58.2 0.0 8.8e-15 54.7 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EKX50468.1 - 2.6e-13 50.5 0.0 4.3e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EKX50468.1 - 2.7e-07 30.9 0.0 6.8e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF3499 PF12005.8 EKX50468.1 - 0.014 16.0 1.2 0.41 11.2 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3499) Glycogen_syn PF05693.13 EKX50468.1 - 0.02 13.5 0.0 0.027 13.0 0.0 1.1 1 0 0 1 1 1 0 Glycogen synthase Glyco_transf_4 PF13439.6 EKX50468.1 - 0.023 14.7 0.0 0.055 13.5 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 ATR13 PF16829.5 EKX50468.1 - 0.031 14.6 0.0 0.069 13.5 0.0 1.5 1 0 0 1 1 1 0 Avirulence protein ATR13, RxLR effector Glyco_trans_4_4 PF13579.6 EKX50468.1 - 0.045 14.2 0.2 0.33 11.4 0.0 2.4 2 1 1 3 3 3 0 Glycosyl transferase 4-like domain DUF92 PF01940.16 EKX50469.1 - 7e-53 179.5 19.1 1.2e-52 178.6 19.1 1.4 1 1 0 1 1 1 1 Integral membrane protein DUF92 RWP-RK PF02042.15 EKX50470.1 - 1.3e-15 57.1 0.1 2e-15 56.5 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_24 PF13412.6 EKX50470.1 - 0.025 14.1 0.1 0.048 13.2 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_17 PF12728.7 EKX50470.1 - 0.033 14.4 0.1 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_r4_2 PF08281.12 EKX50470.1 - 0.036 13.8 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_8 PF02954.19 EKX50470.1 - 0.073 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Pep_deformylase PF01327.21 EKX50472.1 - 1.6e-48 164.3 0.0 2e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase Glyco_transf_4 PF13439.6 EKX50475.1 - 2.7e-26 92.6 0.7 9.7e-26 90.8 0.7 2.0 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EKX50475.1 - 2.9e-21 75.8 0.0 9.4e-21 74.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EKX50475.1 - 1.5e-18 67.8 0.1 6.1e-18 65.8 0.0 2.1 2 2 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 EKX50475.1 - 6.1e-13 49.4 0.0 5.2e-12 46.3 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 EKX50475.1 - 7.6e-11 42.2 3.4 2.4e-08 34.0 3.4 2.8 1 1 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_2 PF13524.6 EKX50475.1 - 1.2e-07 32.0 0.0 2.6e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 EKX50475.1 - 5.5e-06 26.5 0.2 2.1e-05 24.6 0.2 1.9 1 1 0 2 2 2 1 Glycosyl transferase 4-like ArsA_ATPase PF02374.15 EKX50477.1 - 2.3e-102 342.3 0.1 3.3e-102 341.8 0.1 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 EKX50477.1 - 8.1e-13 48.7 0.0 3.5e-12 46.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 EKX50477.1 - 9.5e-12 45.1 0.0 2.1e-11 44.0 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 EKX50477.1 - 1.1e-05 25.1 0.0 6.3e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 EKX50477.1 - 9.3e-05 22.0 2.0 0.0014 18.2 0.1 2.5 2 1 1 3 3 3 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 EKX50477.1 - 0.00024 20.7 0.0 0.00052 19.6 0.0 1.6 1 1 1 2 2 2 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 EKX50477.1 - 0.00041 20.0 0.0 0.0047 16.6 0.0 2.4 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain CTP_synth_N PF06418.14 EKX50477.1 - 0.02 14.2 0.5 2 7.6 0.0 2.1 2 0 0 2 2 2 0 CTP synthase N-terminus AAA_24 PF13479.6 EKX50477.1 - 0.026 14.3 0.1 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EKX50477.1 - 0.051 13.3 0.7 0.22 11.3 0.1 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 EKX50477.1 - 0.052 14.1 0.0 0.18 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EKX50477.1 - 0.072 12.3 0.1 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain BALF1 PF06861.11 EKX50477.1 - 0.11 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 BALF1 protein Pkinase PF00069.25 EKX50481.1 - 7.1e-17 61.6 0.0 1.5e-16 60.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX50481.1 - 0.056 12.7 0.8 0.098 11.9 0.0 1.8 3 0 0 3 3 3 0 Protein tyrosine kinase zf-LITAF-like PF10601.9 EKX50483.1 - 2.4e-18 66.1 9.8 2.4e-18 66.1 9.8 1.8 2 0 0 2 2 2 1 LITAF-like zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 EKX50483.1 - 0.022 14.7 0.3 0.022 14.7 0.3 2.7 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Rad50_zn_hook PF04423.14 EKX50483.1 - 0.93 9.4 5.5 2.2 8.2 0.6 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-H2C2_2 PF13465.6 EKX50483.1 - 2.2 8.9 7.5 17 6.0 2.0 2.8 2 0 0 2 2 2 0 Zinc-finger double domain Glyco_hydro_47 PF01532.20 EKX50485.1 - 1.2e-104 350.8 0.2 1.7e-104 350.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 MFS_1_like PF12832.7 EKX50486.1 - 9.3e-63 212.4 16.2 1.3e-62 211.9 16.2 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 EKX50486.1 - 2.4e-23 82.7 22.8 4.5e-21 75.2 11.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 EKX50486.1 - 7.8e-09 35.0 19.8 2.1e-05 23.7 3.8 2.2 2 0 0 2 2 2 2 Nucleoside H+ symporter ATG22 PF11700.8 EKX50486.1 - 0.00011 21.0 7.6 0.00011 21.0 7.6 2.1 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like BT1 PF03092.16 EKX50486.1 - 0.00024 19.5 4.6 0.0016 16.8 1.4 2.4 1 1 0 2 2 2 2 BT1 family DUF3487 PF11990.8 EKX50486.1 - 0.065 13.1 0.2 0.065 13.1 0.2 4.0 4 1 1 5 5 5 0 Protein of unknown function (DUF3487) Glyco_transf_4 PF13439.6 EKX50488.1 - 0.0031 17.5 0.0 0.0079 16.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 EKX50488.1 - 0.062 13.7 0.0 0.18 12.2 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 DUF3119 PF11317.8 EKX50489.1 - 9.9e-34 116.3 0.0 1.2e-33 116.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3119) WW PF00397.26 EKX50490.1 - 2.7e-09 37.0 0.9 4.8e-09 36.1 0.9 1.4 1 0 0 1 1 1 1 WW domain WDCP PF15390.6 EKX50491.1 - 0.047 12.1 2.2 0.066 11.6 2.2 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF2235 PF09994.9 EKX50491.1 - 0.054 12.8 0.5 0.097 12.0 0.5 1.4 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) UNC-79 PF14776.6 EKX50491.1 - 0.096 11.4 2.8 0.15 10.8 2.8 1.2 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 PRIMA1 PF16101.5 EKX50491.1 - 0.1 12.7 1.6 0.26 11.3 1.6 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 RabGAP-TBC PF00566.18 EKX50491.1 - 0.1 12.2 2.6 0.16 11.6 2.6 1.3 1 0 0 1 1 1 0 Rab-GTPase-TBC domain Mur_ligase_M PF08245.12 EKX50491.1 - 0.11 12.5 3.1 0.24 11.3 3.0 1.6 1 1 0 1 1 1 0 Mur ligase middle domain Atg14 PF10186.9 EKX50491.1 - 0.19 10.8 8.2 0.39 9.7 8.2 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_23 PF13476.6 EKX50491.1 - 0.22 12.0 6.9 0.49 10.9 6.9 1.7 1 0 0 1 1 1 0 AAA domain DUF3391 PF11871.8 EKX50491.1 - 6.1 7.4 12.2 14 6.2 3.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) DUF4407 PF14362.6 EKX50491.1 - 9 5.5 9.4 14 5.0 3.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) 3HCDH_N PF02737.18 EKX50492.1 - 3.4e-58 196.5 0.1 5e-58 196.0 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EKX50492.1 - 1e-24 86.9 0.4 2.1e-11 44.3 0.1 3.7 2 1 1 3 3 3 3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.23 EKX50492.1 - 0.00037 20.5 0.1 0.00065 19.7 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 EKX50492.1 - 0.00076 19.7 0.1 0.0017 18.6 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.27 EKX50492.1 - 0.0026 18.3 0.1 0.0065 17.0 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EKX50492.1 - 0.0041 16.4 0.0 0.008 15.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EKX50492.1 - 0.0043 16.7 0.0 0.0086 15.7 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 EKX50492.1 - 0.022 14.3 0.0 0.046 13.3 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 EKX50492.1 - 0.024 14.9 0.0 0.048 13.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DAO PF01266.24 EKX50492.1 - 0.03 13.9 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EKX50492.1 - 0.04 14.1 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AAA_31 PF13614.6 EKX50492.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain F420_oxidored PF03807.17 EKX50492.1 - 0.083 13.5 0.6 0.24 12.0 0.1 2.2 2 1 0 2 2 1 0 NADP oxidoreductase coenzyme F420-dependent Cutinase PF01083.22 EKX50492.1 - 0.18 11.8 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Cutinase Parvo_coat_N PF08398.10 EKX50493.1 - 0.067 13.3 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus coat protein VP1 EF-hand_1 PF00036.32 EKX50495.1 - 1.3e-09 36.9 1.0 1.7e-05 24.0 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX50495.1 - 2.3e-08 34.4 2.3 6.5e-08 32.9 2.3 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX50495.1 - 8.9e-08 31.3 6.6 9.9e-06 24.8 0.5 3.2 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EKX50495.1 - 9.2e-08 31.4 1.2 0.011 15.6 0.1 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EKX50495.1 - 2.7e-06 27.1 5.3 7.3e-06 25.7 0.7 3.2 3 1 1 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX50495.1 - 6.6e-05 23.2 0.0 0.00014 22.2 0.0 1.5 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region TRP PF06011.12 EKX50498.1 - 0.16 10.7 9.4 0.067 11.9 6.6 1.6 1 1 1 2 2 2 0 Transient receptor potential (TRP) ion channel Phage_holin_3_6 PF07332.11 EKX50498.1 - 1.6 8.8 4.4 19 5.3 0.4 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III WD40 PF00400.32 EKX50499.1 - 8 7.5 5.7 5.2 8.1 0.4 3.3 4 0 0 4 4 4 0 WD domain, G-beta repeat Histone PF00125.24 EKX50500.1 - 3.5e-19 69.5 0.6 4.3e-19 69.2 0.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EKX50500.1 - 0.00024 21.3 0.0 0.00045 20.5 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EKX50500.1 - 0.0015 19.0 0.0 0.0027 18.2 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 EKX50500.1 - 0.013 15.5 1.5 0.016 15.2 1.5 1.2 1 0 0 1 1 1 0 YscO-like protein RWP-RK PF02042.15 EKX50501.1 - 1.1e-12 47.7 0.1 2e-12 46.9 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain CPSase_C PF18302.1 EKX50501.1 - 0.14 12.6 0.1 0.46 11.0 0.0 1.9 2 0 0 2 2 2 0 Carbamoyl phosphate synthetase C-terminal domain RWP-RK PF02042.15 EKX50502.1 - 1.3e-12 47.5 0.1 2.9e-12 46.4 0.1 1.6 2 0 0 2 2 2 1 RWP-RK domain Caveolin PF01146.17 EKX50504.1 - 2.8 7.9 6.5 0.56 10.2 3.0 1.6 2 0 0 2 2 2 0 Caveolin DUF2062 PF09835.9 EKX50504.1 - 3.7 7.4 13.7 34 4.3 13.7 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Aldo_ket_red PF00248.21 EKX50505.1 - 1.3e-45 155.8 0.0 7.1e-43 146.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family LCIB_C_CA PF18599.1 EKX50506.1 - 5.6e-48 163.1 0.0 6.3e-48 163.0 0.0 1.0 1 0 0 1 1 1 1 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Histone PF00125.24 EKX50507.1 - 2.9e-19 69.7 0.3 3.7e-19 69.4 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EKX50507.1 - 0.00026 21.2 0.0 0.0005 20.3 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EKX50507.1 - 0.0016 18.9 0.0 0.003 18.0 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 EKX50507.1 - 0.011 15.7 1.1 0.015 15.4 1.1 1.2 1 0 0 1 1 1 0 YscO-like protein Histone PF00125.24 EKX50508.1 - 2.9e-19 69.7 0.3 3.7e-19 69.4 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EKX50508.1 - 0.00026 21.2 0.0 0.0005 20.3 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EKX50508.1 - 0.0016 18.9 0.0 0.003 18.0 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 EKX50508.1 - 0.011 15.7 1.1 0.015 15.4 1.1 1.2 1 0 0 1 1 1 0 YscO-like protein PAS_11 PF14598.6 EKX50512.1 - 0.046 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 PAS domain EF-hand_1 PF00036.32 EKX50513.1 - 1.8e-10 39.6 0.8 2.5e-05 23.5 0.3 4.9 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 EKX50513.1 - 2e-07 30.8 0.1 0.0085 15.9 0.2 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 EKX50513.1 - 3.2e-07 30.7 0.7 0.0091 16.4 1.2 3.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX50513.1 - 3.7e-05 23.3 0.2 0.044 13.7 0.0 4.1 4 0 0 4 4 4 1 EF-hand domain EF-hand_5 PF13202.6 EKX50513.1 - 0.00021 20.7 2.9 0.00023 20.5 0.3 2.6 2 0 0 2 2 2 1 EF hand DUF4834 PF16118.5 EKX50513.1 - 0.86 10.6 8.8 41 5.2 0.0 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF4834) Mlo PF03094.15 EKX50513.1 - 1.8 6.8 12.9 3.2 6.0 1.1 3.6 4 0 0 4 4 4 0 Mlo family Ion_trans PF00520.31 EKX50515.1 - 8.8e-35 120.1 25.3 1.3e-34 119.5 25.3 1.2 1 0 0 1 1 1 1 Ion transport protein C2 PF00168.30 EKX50515.1 - 4.1e-13 49.5 0.0 7.1e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain PKD_channel PF08016.12 EKX50515.1 - 0.00092 18.0 20.4 0.0036 16.0 20.4 1.9 1 1 0 1 1 1 1 Polycystin cation channel PH_2 PF08458.10 EKX50515.1 - 0.022 15.1 0.0 0.05 14.0 0.0 1.6 1 0 0 1 1 1 0 Plant pleckstrin homology-like region PH PF00169.29 EKX50515.1 - 0.1 13.1 0.0 0.27 11.8 0.0 1.8 1 0 0 1 1 1 0 PH domain PDZ_2 PF13180.6 EKX50516.1 - 2.8e-09 37.1 0.6 7.6e-09 35.8 0.6 1.7 1 0 0 1 1 1 1 PDZ domain C2 PF00168.30 EKX50516.1 - 4.9e-09 36.4 0.1 1.4e-08 34.9 0.1 1.9 1 0 0 1 1 1 1 C2 domain HC2 PF07382.11 EKX50516.1 - 8.7e-07 29.2 24.5 1.7e-06 28.3 24.5 1.4 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 PDZ_6 PF17820.1 EKX50516.1 - 9.1e-07 28.6 0.1 2e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX50516.1 - 2.7e-06 27.6 0.2 6.4e-06 26.4 0.2 1.6 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX50516.1 - 0.0014 18.5 0.7 0.0059 16.5 0.1 2.5 2 1 0 2 2 2 1 Tricorn protease PDZ domain Hamartin PF04388.12 EKX50516.1 - 0.75 8.4 33.8 0.055 12.1 27.1 2.0 2 0 0 2 2 2 0 Hamartin protein CRISPR_Cas2 PF09827.9 EKX50517.1 - 0.0042 17.3 0.0 0.0083 16.3 0.0 1.5 1 0 0 1 1 1 1 CRISPR associated protein Cas2 SAM_1 PF00536.30 EKX50517.1 - 0.17 12.4 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) 2OG-FeII_Oxy_2 PF13532.6 EKX50518.1 - 1.1e-11 45.3 0.0 2.2e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CorC_HlyC PF03471.17 EKX50518.1 - 0.16 12.0 0.0 0.81 9.7 0.0 2.0 2 0 0 2 2 2 0 Transporter associated domain RWP-RK PF02042.15 EKX50519.1 - 3.3e-07 30.2 0.0 4.6e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain Rhomboid_SP PF12595.8 EKX50519.1 - 0.0072 15.7 0.2 0.0077 15.6 0.2 1.1 1 0 0 1 1 1 1 Rhomboid serine protease Myotub-related PF06602.14 EKX50520.1 - 7.4e-91 304.7 0.0 1.1e-90 304.1 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 EKX50520.1 - 0.002 18.1 0.0 0.0034 17.4 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Histone PF00125.24 EKX50521.1 - 3.5e-19 69.5 0.6 4.3e-19 69.2 0.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EKX50521.1 - 0.00024 21.3 0.0 0.00045 20.5 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EKX50521.1 - 0.0015 19.0 0.0 0.0027 18.2 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 EKX50521.1 - 0.013 15.5 1.5 0.016 15.2 1.5 1.2 1 0 0 1 1 1 0 YscO-like protein HMMR_C PF15908.5 EKX50522.1 - 0.046 14.0 1.4 0.093 13.0 1.4 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal Cep57_MT_bd PF06657.13 EKX50522.1 - 0.061 13.8 2.1 0.15 12.6 2.1 1.7 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 ChW PF07538.11 EKX50522.1 - 0.086 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Clostridial hydrophobic W WD40_alt PF14077.6 EKX50522.1 - 0.1 12.5 0.3 0.25 11.3 0.3 1.6 1 0 0 1 1 1 0 Alternative WD40 repeat motif JIP_LZII PF16471.5 EKX50522.1 - 0.11 12.7 1.6 0.22 11.7 1.6 1.6 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II HALZ PF02183.18 EKX50522.1 - 1 9.7 8.6 4.8 7.5 0.6 2.4 1 1 1 2 2 2 0 Homeobox associated leucine zipper ADIP PF11559.8 EKX50522.1 - 1.3 9.1 6.4 0.4 10.7 3.4 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Beach PF02138.18 EKX50523.1 - 9.6e-107 356.5 0.0 1.1e-106 356.3 0.0 1.0 1 0 0 1 1 1 1 Beige/BEACH domain Pex19 PF04614.12 EKX50523.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Pex19 protein family EF-hand_7 PF13499.6 EKX50524.1 - 2.8e-17 62.9 4.2 1.3e-12 48.0 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX50524.1 - 3.7e-11 42.0 3.6 1.7e-05 24.4 0.1 4.9 3 2 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EKX50524.1 - 5.3e-11 41.2 9.2 8.8e-06 24.9 0.1 4.9 5 1 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 EKX50524.1 - 1.1e-06 28.4 5.3 0.062 13.2 0.3 4.5 3 1 2 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 EKX50524.1 - 6.8e-06 25.4 3.8 0.00018 20.9 0.0 3.6 4 0 0 4 4 4 1 EF hand EF-hand_9 PF14658.6 EKX50524.1 - 7.9e-06 26.1 0.2 0.019 15.3 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain HisK_N PF09385.10 EKX50524.1 - 0.007 16.3 0.4 1.5 8.8 0.1 2.2 2 0 0 2 2 2 2 Histidine kinase N terminal SPARC_Ca_bdg PF10591.9 EKX50524.1 - 0.036 14.4 0.1 0.068 13.5 0.0 1.6 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Imm30 PF15565.6 EKX50524.1 - 0.059 13.4 0.4 0.17 11.9 0.1 1.8 1 1 1 2 2 2 0 Immunity protein 30 EF-hand_4 PF12763.7 EKX50524.1 - 0.16 11.9 4.0 4.6 7.2 0.1 2.9 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand DUF1843 PF08898.10 EKX50525.1 - 0.16 12.5 0.5 0.42 11.1 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) AAA PF00004.29 EKX50526.1 - 2e-38 131.8 0.0 1.5e-37 129.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EKX50526.1 - 1.1e-09 38.0 0.1 6.1e-09 35.5 0.1 2.3 1 1 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EKX50526.1 - 6.6e-06 25.9 0.0 1.9e-05 24.4 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EKX50526.1 - 2.3e-05 24.4 0.2 0.00016 21.7 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EKX50526.1 - 0.00026 21.4 0.4 0.071 13.5 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain Sigma54_activat PF00158.26 EKX50526.1 - 0.00045 20.0 0.0 0.045 13.4 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.6 EKX50526.1 - 0.00098 19.3 0.1 0.0058 16.8 0.0 2.0 1 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 EKX50526.1 - 0.0016 17.8 0.0 0.0025 17.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 EKX50526.1 - 0.0029 17.8 0.0 0.0066 16.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EKX50526.1 - 0.0031 16.7 0.0 0.005 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 EKX50526.1 - 0.0035 17.9 0.0 0.0082 16.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EKX50526.1 - 0.0064 16.2 0.0 0.029 14.1 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein Vps4_C PF09336.10 EKX50526.1 - 0.0074 16.3 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain Bac_DnaA PF00308.18 EKX50526.1 - 0.0095 15.8 0.2 0.046 13.6 0.2 1.9 1 1 0 1 1 1 1 Bacterial dnaA protein AAA_22 PF13401.6 EKX50526.1 - 0.01 16.1 0.1 0.1 12.9 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EKX50526.1 - 0.011 15.8 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EKX50526.1 - 0.014 14.8 0.0 0.025 13.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EKX50526.1 - 0.015 15.6 0.0 0.052 14.0 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.6 EKX50526.1 - 0.016 14.8 0.1 0.56 9.7 0.0 2.4 1 1 0 2 2 2 0 AAA domain TniB PF05621.11 EKX50526.1 - 0.043 13.2 0.0 4.8 6.6 0.0 2.5 1 1 1 2 2 2 0 Bacterial TniB protein AAA_17 PF13207.6 EKX50526.1 - 0.047 14.1 0.0 0.2 12.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EKX50526.1 - 0.05 13.5 0.0 0.5 10.3 0.0 2.2 1 1 1 2 2 2 0 NACHT domain AAA_3 PF07726.11 EKX50526.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EKX50526.1 - 0.094 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EKX50526.1 - 0.11 11.9 0.0 0.5 9.9 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase PF06745.13 EKX50526.1 - 0.15 11.4 0.1 6.1 6.1 0.0 2.3 1 1 1 2 2 2 0 KaiC Zot PF05707.12 EKX50526.1 - 0.15 11.7 0.1 0.75 9.4 0.0 2.0 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) Zeta_toxin PF06414.12 EKX50526.1 - 0.15 11.3 0.0 0.37 10.0 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin Band_7 PF01145.25 EKX50527.1 - 1.8e-16 60.7 2.9 1.8e-16 60.7 2.9 1.9 1 1 1 2 2 2 1 SPFH domain / Band 7 family SPG4 PF17325.2 EKX50527.1 - 0.46 11.6 5.7 0.62 11.2 3.0 2.1 1 1 1 2 2 2 0 Stationary phase protein 4 Bromodomain PF00439.25 EKX50528.1 - 2.9e-13 49.7 0.0 3.3e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Bromodomain Bromodomain PF00439.25 EKX50529.1 - 6.9e-16 58.1 0.1 1e-15 57.6 0.1 1.2 1 0 0 1 1 1 1 Bromodomain Bromodomain PF00439.25 EKX50530.1 - 1.1e-15 57.5 0.2 1.2e-15 57.3 0.2 1.0 1 0 0 1 1 1 1 Bromodomain LRR_8 PF13855.6 EKX50531.1 - 1.5e-54 181.6 78.9 5.8e-09 35.6 4.9 11.9 2 2 11 13 13 13 13 Leucine rich repeat LRR_4 PF12799.7 EKX50531.1 - 2.6e-48 161.2 87.0 2.1e-05 24.8 3.7 14.6 8 3 7 16 16 16 15 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX50531.1 - 5.9e-05 23.1 56.6 12 6.9 0.3 17.7 20 3 0 20 20 20 2 Leucine Rich Repeat PLU-1 PF08429.11 EKX50531.1 - 0.0013 18.0 2.9 0.0065 15.7 1.1 2.9 1 1 2 3 3 3 1 PLU-1-like protein POTRA_3 PF17287.2 EKX50531.1 - 0.014 14.8 6.0 14 5.2 0.0 5.0 4 1 1 5 5 5 0 POTRA domain HypF_C PF17788.1 EKX50531.1 - 0.047 14.4 0.1 67 4.3 0.0 5.0 4 2 3 8 8 8 0 HypF Kae1-like domain LRR_8 PF13855.6 EKX50532.1 - 1.6e-30 104.7 63.3 1.3e-10 40.9 5.1 4.9 3 1 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 EKX50532.1 - 2e-19 69.4 51.8 6.6e-05 23.2 2.0 7.2 3 3 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX50532.1 - 0.0095 15.5 21.9 0.014 14.9 3.4 3.9 1 1 2 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 EKX50532.1 - 0.09 12.9 0.2 0.09 12.9 0.2 9.0 10 0 0 10 10 10 0 Leucine Rich repeat CSTF_C PF14304.6 EKX50532.1 - 0.58 9.8 7.5 47 3.7 0.3 5.2 6 0 0 6 6 6 0 Transcription termination and cleavage factor C-terminal LRR_1 PF00560.33 EKX50532.1 - 3 8.8 40.4 6.5 7.7 0.2 9.3 8 3 2 10 10 10 0 Leucine Rich Repeat LRR_8 PF13855.6 EKX50533.1 - 1.8e-54 181.3 150.2 1.2e-07 31.4 0.2 10.7 1 1 14 15 15 15 15 Leucine rich repeat LRR_4 PF12799.7 EKX50533.1 - 5.8e-48 160.1 92.7 4.3e-06 27.0 0.7 12.7 5 3 6 13 13 13 13 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX50533.1 - 2.3e-07 30.5 49.0 0.26 10.8 2.3 7.4 1 1 7 8 8 8 8 Leucine-rich repeat LRR_5 PF13306.6 EKX50533.1 - 1.7e-05 24.8 6.1 0.0052 16.7 0.2 4.1 3 1 1 4 4 4 2 BspA type Leucine rich repeat region (6 copies) RsmF_methylt_CI PF17126.5 EKX50533.1 - 0.002 18.1 1.6 2.4 8.3 0.1 5.6 4 2 1 6 6 6 1 RsmF rRNA methyltransferase first C-terminal domain LRR_1 PF00560.33 EKX50533.1 - 0.0041 17.4 74.0 1.4 9.8 0.5 18.3 19 2 1 20 20 20 2 Leucine Rich Repeat Dynamitin PF04912.14 EKX50533.1 - 0.28 10.5 1.8 12 5.0 0.2 2.5 2 0 0 2 2 2 0 Dynamitin LRR_6 PF13516.6 EKX50535.1 - 1.4e-17 62.1 28.6 0.013 15.5 0.3 12.1 13 0 0 13 13 13 7 Leucine Rich repeat LRR_4 PF12799.7 EKX50535.1 - 0.00049 20.4 31.3 0.19 12.2 0.7 8.5 7 2 4 11 11 11 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX50535.1 - 0.0064 16.2 30.1 7.8 6.4 0.0 8.8 7 3 0 8 8 8 5 Leucine rich repeat LRR_9 PF14580.6 EKX50535.1 - 0.009 15.5 0.8 1.4 8.4 0.1 3.0 2 1 1 3 3 3 2 Leucine-rich repeat Collagen PF01391.18 EKX50536.1 - 7.7e-18 64.0 71.4 1.8e+02 2.0 71.4 2.9 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Laminin_G_3 PF13385.6 EKX50537.1 - 4.4e-12 46.4 0.4 5.8e-12 46.0 0.4 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Pentaxin PF00354.17 EKX50537.1 - 1.3e-09 38.0 0.1 1.7e-09 37.6 0.1 1.1 1 0 0 1 1 1 1 Pentaxin family Laminin_G_2 PF02210.24 EKX50537.1 - 1.4e-05 25.7 0.1 3.9e-05 24.2 0.1 1.7 2 0 0 2 2 2 1 Laminin G domain Polysacc_lyase PF14099.6 EKX50537.1 - 0.028 14.3 0.2 0.04 13.8 0.2 1.2 1 0 0 1 1 1 0 Polysaccharide lyase MHC_II_alpha PF00993.20 EKX50537.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Class II histocompatibility antigen, alpha domain SKI PF01202.22 EKX50538.1 - 9.4e-17 61.6 0.0 1e-16 61.4 0.0 1.0 1 0 0 1 1 1 1 Shikimate kinase Cytidylate_kin2 PF13189.6 EKX50538.1 - 0.00022 21.4 0.1 0.00039 20.6 0.0 1.4 1 1 1 2 2 2 1 Cytidylate kinase-like family Cytidylate_kin PF02224.18 EKX50538.1 - 0.017 14.9 0.0 0.017 14.9 0.0 1.1 1 0 0 1 1 1 0 Cytidylate kinase Lip_prot_lig_C PF10437.9 EKX50538.1 - 0.025 14.5 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus AAA_17 PF13207.6 EKX50538.1 - 0.051 14.0 0.0 0.056 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain WSN PF02206.18 EKX50538.1 - 0.076 12.9 0.0 1.5 8.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function Macoilin PF09726.9 EKX50539.1 - 0.0013 17.4 32.3 0.0017 17.0 32.3 1.1 1 0 0 1 1 1 1 Macoilin family TetR_C_20 PF17925.1 EKX50539.1 - 0.049 14.0 3.4 0.29 11.4 2.5 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF1664 PF07889.12 EKX50539.1 - 5.1 7.2 8.9 1.3 9.0 1.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Dpy-30 PF05186.13 EKX50540.1 - 5.7e-15 54.7 0.1 1.1e-14 53.8 0.1 1.5 1 0 0 1 1 1 1 Dpy-30 motif NPIP PF06409.11 EKX50540.1 - 0.093 11.8 1.9 0.16 11.0 1.9 1.2 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) TRIF-NTD PF17798.1 EKX50540.1 - 0.22 11.6 6.7 0.039 14.1 2.0 2.0 2 0 0 2 2 2 0 TRIF N-terminal domain tRNA_anti-like PF12869.7 EKX50540.1 - 1.5 8.4 5.7 2.5 7.7 1.9 2.3 2 0 0 2 2 2 0 tRNA_anti-like DUF5560 PF17715.1 EKX50540.1 - 6.3 6.2 8.2 1.6 8.2 0.8 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5560) zf-RING_2 PF13639.6 EKX50542.1 - 4.4e-07 30.1 10.4 8.4e-07 29.2 10.4 1.5 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 EKX50542.1 - 2.3e-06 27.7 9.3 7.3e-06 26.1 9.3 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.25 EKX50542.1 - 0.00073 19.4 11.6 0.0013 18.6 11.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX50542.1 - 0.0012 19.1 13.5 0.0051 17.1 12.2 2.4 2 1 1 3 3 3 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EKX50542.1 - 0.0016 18.4 6.1 0.0035 17.4 6.1 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 EKX50542.1 - 0.003 17.6 7.3 0.0064 16.6 7.3 1.6 1 1 0 1 1 1 1 RING-variant domain zf-RING-like PF08746.11 EKX50542.1 - 0.0055 17.0 5.0 0.0055 17.0 5.0 2.0 2 0 0 2 2 2 1 RING-like domain zf-C3HC4_3 PF13920.6 EKX50542.1 - 0.0085 15.9 6.5 0.74 9.7 3.7 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 EKX50542.1 - 0.011 15.6 7.1 0.021 14.7 7.1 1.5 1 0 0 1 1 1 0 PHD-finger GAGA PF09237.11 EKX50542.1 - 0.012 15.4 1.4 0.93 9.3 0.0 2.3 2 0 0 2 2 2 0 GAGA factor Zn_ribbon_17 PF17120.5 EKX50542.1 - 0.015 14.9 7.6 0.037 13.6 7.6 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 EKX50542.1 - 0.019 14.8 11.9 0.049 13.5 11.9 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 EKX50542.1 - 0.53 10.2 8.5 0.1 12.5 3.9 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rad50_zn_hook PF04423.14 EKX50542.1 - 0.6 10.0 3.0 2.8 7.8 0.4 2.7 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-RING_6 PF14835.6 EKX50542.1 - 1.4 8.8 5.8 5.1 7.0 1.1 2.4 1 1 1 2 2 2 0 zf-RING of BARD1-type protein Zf_RING PF16744.5 EKX50542.1 - 2.9 8.0 7.0 12 6.1 7.0 2.1 1 1 0 1 1 1 0 KIAA1045 RING finger RecR PF02132.15 EKX50542.1 - 3.6 7.3 7.3 13 5.4 2.2 2.8 2 1 0 2 2 2 0 RecR protein zf-RING_4 PF14570.6 EKX50542.1 - 5.7 6.8 8.4 5.7 6.8 6.5 2.0 2 1 0 2 2 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EKX50542.1 - 6.1 6.8 13.8 7.3 6.5 6.0 3.0 2 1 2 4 4 3 0 Prokaryotic RING finger family 4 PHD_4 PF16866.5 EKX50542.1 - 6.6 6.9 9.5 27 4.9 0.2 2.7 1 1 1 2 2 2 0 PHD-finger Myb_DNA-binding PF00249.31 EKX50543.1 - 0.011 15.9 1.9 0.016 15.4 0.2 2.2 2 1 0 2 2 2 0 Myb-like DNA-binding domain UPF0183 PF03676.14 EKX50544.1 - 2.8e-21 76.3 0.0 6.6e-20 71.8 0.2 2.0 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0183) RNA_pol_3_Rpc31 PF11705.8 EKX50544.1 - 0.0016 18.7 14.3 0.0018 18.6 14.3 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.12 EKX50544.1 - 0.0052 16.6 13.7 0.0061 16.3 13.7 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Afi1 PF07792.12 EKX50544.1 - 0.021 15.3 2.8 0.022 15.2 2.8 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking BUD22 PF09073.10 EKX50544.1 - 0.052 12.9 13.1 0.059 12.7 13.1 1.1 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 EKX50544.1 - 0.054 13.1 13.9 0.06 12.9 13.9 1.1 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 EKX50544.1 - 0.078 12.4 13.8 0.081 12.3 13.8 1.1 1 0 0 1 1 1 0 SDA1 DUF913 PF06025.12 EKX50544.1 - 0.33 9.9 0.9 0.35 9.8 0.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Astro_capsid_p PF12226.8 EKX50544.1 - 1.6 7.8 13.5 1.8 7.6 13.5 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop14 PF04147.12 EKX50544.1 - 2.3 6.3 19.8 2.6 6.1 19.8 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 EKX50544.1 - 4.2 7.1 14.4 4.1 7.1 12.9 1.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein NOA36 PF06524.12 EKX50544.1 - 4.8 6.4 24.3 6.7 5.9 24.3 1.2 1 0 0 1 1 1 0 NOA36 protein SQS_PSY PF00494.19 EKX50545.1 - 2.7e-39 135.2 0.0 5.4e-39 134.3 0.0 1.4 2 0 0 2 2 2 1 Squalene/phytoene synthase DUF4267 PF14087.6 EKX50545.1 - 0.088 12.9 0.2 0.34 11.0 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4267) DUF4215 PF13948.6 EKX50546.1 - 1.1e-06 28.9 1.6 1.1e-06 28.9 1.6 4.2 4 0 0 4 4 4 1 Domain of unknown function (DUF4215) Kinesin PF00225.23 EKX50547.1 - 1.5e-96 323.2 0.1 2.2e-96 322.7 0.1 1.3 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX50547.1 - 2.2e-49 167.2 0.0 5.9e-49 165.8 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding AATF-Che1 PF13339.6 EKX50547.1 - 0.14 12.8 0.3 0.14 12.8 0.3 2.8 2 1 0 3 3 3 0 Apoptosis antagonizing transcription factor NPV_P10 PF05531.12 EKX50547.1 - 0.15 12.6 2.1 1.5 9.3 0.7 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 EKX50547.1 - 0.15 10.9 12.7 0.014 14.3 7.4 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein HAP1_N PF04849.13 EKX50547.1 - 0.51 9.5 13.8 0.2 10.8 7.9 2.4 2 0 0 2 2 2 0 HAP1 N-terminal conserved region FliD_N PF02465.18 EKX50547.1 - 0.61 10.8 4.7 0.63 10.8 0.4 2.8 3 0 0 3 3 2 0 Flagellar hook-associated protein 2 N-terminus DUF1664 PF07889.12 EKX50547.1 - 0.86 9.7 5.2 1.4 9.0 4.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TPD52 PF04201.15 EKX50547.1 - 0.89 9.1 7.0 2.1 7.9 5.7 2.2 2 0 0 2 2 2 0 Tumour protein D52 family FapA PF03961.13 EKX50547.1 - 1.6 7.3 7.9 0.31 9.6 3.0 1.9 2 0 0 2 2 2 0 Flagellar Assembly Protein A FlaC_arch PF05377.11 EKX50547.1 - 1.8 9.0 5.3 6.7 7.2 0.9 3.0 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) Occludin_ELL PF07303.13 EKX50547.1 - 2 9.2 5.5 6.9 7.5 4.1 2.4 2 0 0 2 2 2 0 Occludin homology domain DUF1151 PF06625.11 EKX50547.1 - 3.5 7.6 17.3 0.29 11.1 10.8 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1151) KELK PF15796.5 EKX50547.1 - 4.8 7.7 17.1 8.7 6.9 10.1 3.4 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase SlyX PF04102.12 EKX50547.1 - 5.1 7.8 8.8 3.8 8.2 5.5 2.6 2 0 0 2 2 1 0 SlyX Syntaxin-6_N PF09177.11 EKX50547.1 - 6.2 7.4 8.7 26 5.4 1.4 3.1 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF4407 PF14362.6 EKX50547.1 - 7.5 5.8 8.4 0.85 8.9 3.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) zf-C3HC4_2 PF13923.6 EKX50550.1 - 2.9e-11 43.0 13.9 4.4e-11 42.4 13.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX50550.1 - 8.6e-09 35.1 16.0 1.3e-08 34.5 16.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EKX50550.1 - 2.5e-08 33.7 11.9 3.9e-08 33.0 11.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX50550.1 - 4.1e-08 33.4 14.8 7e-08 32.7 14.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.6 EKX50550.1 - 9.7e-07 28.6 6.7 1.3e-06 28.2 6.1 1.5 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 EKX50550.1 - 1.5e-05 24.9 14.1 2.2e-05 24.3 14.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EKX50550.1 - 0.0011 19.0 12.6 0.0019 18.2 12.6 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 EKX50550.1 - 0.0015 18.3 10.8 0.004 16.9 10.8 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EKX50550.1 - 0.011 15.7 3.7 0.021 14.9 3.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EKX50550.1 - 0.043 14.1 8.8 0.043 14.1 8.8 2.2 1 1 1 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EKX50550.1 - 0.073 13.2 12.3 0.13 12.4 12.3 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EKX50550.1 - 0.092 12.5 7.8 0.3 10.9 7.8 2.0 1 0 0 1 1 1 0 RING-like zinc finger zf-Nse PF11789.8 EKX50550.1 - 0.52 10.2 8.5 0.88 9.4 8.5 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit SET PF00856.28 EKX50551.1 - 1.7e-13 51.3 0.0 1.4e-12 48.3 0.0 2.0 1 1 0 1 1 1 1 SET domain AWS PF17907.1 EKX50551.1 - 5.3e-07 29.6 9.0 5.3e-07 29.6 9.0 1.9 2 0 0 2 2 2 1 AWS domain Chalcone_2 PF16035.5 EKX50552.1 - 2.8e-08 33.8 2.1 0.00012 21.9 0.0 2.1 1 1 1 2 2 2 2 Chalcone isomerase like Chalcone_3 PF16036.5 EKX50552.1 - 1.6e-06 28.4 0.0 2.9e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 Chalcone isomerase-like Chalcone PF02431.15 EKX50552.1 - 2.7e-06 27.0 0.1 6.3e-06 25.7 0.1 1.5 1 1 0 1 1 1 1 Chalcone-flavanone isomerase RNase_T PF00929.24 EKX50554.1 - 4.8e-10 40.2 0.0 8.2e-07 29.7 0.0 2.7 1 1 0 1 1 1 1 Exonuclease RsbU_N PF08673.10 EKX50554.1 - 0.17 12.0 0.1 0.72 10.0 0.0 2.0 2 0 0 2 2 2 0 Phosphoserine phosphatase RsbU, N-terminal domain Fer4_13 PF13370.6 EKX50555.1 - 6.9e-14 52.1 2.2 9.2e-14 51.7 2.2 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 EKX50555.1 - 7.5e-09 36.2 3.4 2.5e-08 34.5 3.4 1.7 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_21 PF14697.6 EKX50555.1 - 0.0032 17.6 4.3 0.0079 16.3 4.3 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 EKX50555.1 - 0.082 13.0 1.0 0.082 13.0 1.0 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.27 EKX50555.1 - 0.23 11.3 10.5 0.58 10.1 4.5 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Methyltransf_32 PF13679.6 EKX50556.1 - 2.2e-11 44.0 1.1 2e-10 40.9 1.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX50556.1 - 1.5e-06 28.1 0.0 2.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain R3H PF01424.22 EKX50556.1 - 2.7e-06 27.3 0.0 6.2e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 R3H domain MTS PF05175.14 EKX50556.1 - 0.00011 21.8 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EKX50556.1 - 0.002 18.8 0.1 0.0072 17.0 0.1 2.0 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 EKX50556.1 - 0.0036 16.6 0.0 0.0061 15.9 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G TRM13 PF05206.14 EKX50556.1 - 0.0096 15.5 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase TRM13 Methyltransf_12 PF08242.12 EKX50556.1 - 0.012 16.3 0.0 0.024 15.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 EKX50556.1 - 0.015 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EKX50556.1 - 0.03 13.8 0.0 0.052 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase AviRa PF11599.8 EKX50556.1 - 0.075 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa CNP1 PF08750.11 EKX50558.1 - 0.011 15.7 1.4 0.99 9.4 0.5 2.1 2 0 0 2 2 2 0 CNP1-like family Peptidase_S49_N PF08496.10 EKX50558.1 - 0.016 15.3 0.7 0.029 14.4 0.7 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1682 PF07946.14 EKX50558.1 - 0.22 10.7 6.6 0.37 10.0 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) MAS20 PF02064.15 EKX50558.1 - 2.5 8.2 12.4 5.2 7.2 12.3 1.7 1 1 0 1 1 1 0 MAS20 protein import receptor Pkinase PF00069.25 EKX50560.1 - 7.2e-50 169.8 0.0 9.3e-50 169.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX50560.1 - 4.7e-24 85.1 0.0 6.4e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX50560.1 - 5.6e-06 25.4 0.0 9.1e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EKX50560.1 - 0.00033 20.1 0.0 0.00072 18.9 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EKX50560.1 - 0.0072 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EKX50560.1 - 0.009 15.7 0.0 3.2 7.3 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EKX50560.1 - 0.04 13.5 0.0 0.068 12.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family HpuA PF16960.5 EKX50560.1 - 0.16 11.1 0.0 0.33 10.0 0.0 1.5 1 0 0 1 1 1 0 Haemoglobin-haptoglobin utilisation, porphyrin transporter APH PF01636.23 EKX50560.1 - 0.18 11.7 0.0 1.1 9.1 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family UIM PF02809.20 EKX50561.1 - 0.04 13.8 3.0 0.11 12.4 3.0 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif Nop PF01798.18 EKX50562.1 - 2.3e-86 289.0 0.1 2.3e-86 289.0 0.1 2.0 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EKX50562.1 - 4.2e-22 78.3 1.6 4.2e-22 78.3 1.6 2.4 2 1 0 2 2 2 1 NOP5NT (NUC127) domain DUF4604 PF15377.6 EKX50562.1 - 0.00043 20.7 23.3 0.00083 19.8 23.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DUF4800 PF16057.5 EKX50562.1 - 1.8 7.8 10.5 3.3 6.9 10.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4800) PDZ_6 PF17820.1 EKX50563.1 - 1.7e-16 59.8 0.9 7.4e-08 32.1 0.8 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX50563.1 - 1.5e-14 54.0 2.1 3.9e-06 27.1 0.3 2.5 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 EKX50563.1 - 1.1e-13 51.3 1.4 3e-09 37.1 0.7 2.6 3 0 0 3 3 3 2 PDZ domain Tricorn_PDZ PF14685.6 EKX50563.1 - 9e-05 22.4 0.1 0.25 11.3 0.0 2.5 2 0 0 2 2 2 2 Tricorn protease PDZ domain UreE_N PF02814.15 EKX50563.1 - 0.0083 15.7 0.2 0.034 13.7 0.1 2.0 2 0 0 2 2 2 1 UreE urease accessory protein, N-terminal domain zf-C2H2 PF00096.26 EKX50564.1 - 3.6e-05 24.0 26.7 0.035 14.5 0.5 6.9 6 0 0 6 6 6 3 Zinc finger, C2H2 type EF-hand_6 PF13405.6 EKX50564.1 - 0.00031 20.4 0.0 0.21 11.6 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain zf-C2H2_aberr PF17017.5 EKX50564.1 - 0.00039 20.6 0.4 3.1 7.9 0.0 4.1 4 0 0 4 4 4 1 Aberrant zinc-finger EF-hand_7 PF13499.6 EKX50564.1 - 0.00039 20.8 0.6 0.021 15.2 0.1 3.0 2 1 0 2 2 2 1 EF-hand domain pair zf-H2C2_2 PF13465.6 EKX50564.1 - 0.0024 18.2 0.3 0.0024 18.2 0.3 4.9 6 0 0 6 6 6 1 Zinc-finger double domain EF-hand_1 PF00036.32 EKX50564.1 - 0.012 15.1 0.2 0.83 9.3 0.0 3.0 3 0 0 3 3 3 0 EF hand zf-C2H2_4 PF13894.6 EKX50564.1 - 0.016 16.0 27.4 0.061 14.2 0.5 6.7 5 1 1 6 6 6 0 C2H2-type zinc finger EF-hand_8 PF13833.6 EKX50564.1 - 0.032 14.1 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair zf-C2H2_11 PF16622.5 EKX50564.1 - 0.038 13.7 7.0 0.22 11.3 0.3 3.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 EKX50564.1 - 0.054 13.5 0.1 0.054 13.5 0.1 5.2 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EKX50564.1 - 4.3 7.7 11.8 2 8.7 0.4 4.4 4 0 0 4 4 4 0 C2H2-type zinc ribbon Membralin PF09746.9 EKX50565.1 - 1 8.3 6.9 1.2 8.0 6.9 1.3 1 0 0 1 1 1 0 Tumour-associated protein WDCP PF15390.6 EKX50565.1 - 1.1 7.6 12.6 1.4 7.2 12.6 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Menin PF05053.13 EKX50565.1 - 1.1 7.5 9.4 1.2 7.4 9.4 1.1 1 0 0 1 1 1 0 Menin Mucin PF01456.17 EKX50565.1 - 1.3 9.0 15.5 5.3 7.0 16.2 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF763 PF05559.11 EKX50565.1 - 1.4 8.0 7.4 1.1 8.4 6.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF763) ATG16 PF08614.11 EKX50565.1 - 1.5 9.0 34.2 8.9 6.5 34.2 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF812 PF05667.11 EKX50565.1 - 1.6 7.5 27.3 2.3 7.0 27.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FAM76 PF16046.5 EKX50565.1 - 1.8 7.8 26.0 2.6 7.3 26.0 1.1 1 0 0 1 1 1 0 FAM76 protein SOBP PF15279.6 EKX50565.1 - 2.4 8.7 12.2 3.2 8.3 12.2 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein CCDC53 PF10152.9 EKX50565.1 - 3 8.2 17.5 3.1 8.2 0.2 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF966 PF06136.13 EKX50565.1 - 6.3 6.4 19.8 8.3 6.0 19.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CDC45 PF02724.14 EKX50565.1 - 7.1 4.8 18.3 9.9 4.3 18.3 1.1 1 0 0 1 1 1 0 CDC45-like protein TEX15 PF15326.6 EKX50565.1 - 7.5 6.2 13.6 6 6.5 11.9 1.6 1 1 1 2 2 2 0 Testis expressed sequence 15 Nop25 PF09805.9 EKX50565.1 - 8.2 6.9 27.8 1.3 9.5 0.7 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) YfdX PF10938.8 EKX50566.1 - 0.047 13.6 0.2 0.2 11.6 0.1 1.9 2 0 0 2 2 2 0 YfdX protein Uricase PF01014.18 EKX50567.1 - 4.8e-46 156.2 0.3 8.9e-33 113.3 0.9 2.4 2 1 0 2 2 2 2 Uricase HAD_2 PF13419.6 EKX50571.1 - 1.7e-09 38.0 0.0 3e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EKX50571.1 - 3.9e-07 30.6 0.0 8.8e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EKX50571.1 - 0.015 15.7 0.0 0.033 14.6 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase EamA PF00892.20 EKX50572.1 - 8.1e-10 39.0 22.4 2.6e-09 37.4 3.3 3.0 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 EKX50572.1 - 0.017 14.3 0.2 0.017 14.3 0.2 2.1 1 1 0 2 2 2 0 Purine nucleobase transmembrane transport Ribosomal_60s PF00428.19 EKX50573.1 - 0.045 14.3 0.7 0.06 13.9 0.7 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein PKcGMP_CC PF16808.5 EKX50574.1 - 0.0018 18.1 0.3 0.0018 18.1 0.3 4.1 3 0 0 3 3 3 1 Coiled-coil N-terminus of cGMP-dependent protein kinase DNA_pol_A_exo1 PF01612.20 EKX50574.1 - 0.029 14.1 0.6 0.056 13.1 0.6 1.5 1 0 0 1 1 1 0 3'-5' exonuclease PDZ_2 PF13180.6 EKX50574.1 - 0.088 13.1 0.0 1 9.8 0.0 2.8 2 1 0 2 2 2 0 PDZ domain Exo84_C PF16528.5 EKX50574.1 - 6.7 6.5 15.1 0.54 10.0 7.1 2.9 2 0 0 2 2 2 0 Exocyst component 84 C-terminal DUF1192 PF06698.11 EKX50574.1 - 8 6.6 17.0 0.12 12.4 0.5 4.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1192) PRMT5 PF05185.16 EKX50575.1 - 3e-67 225.8 0.0 4.1e-67 225.3 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 EKX50575.1 - 5.2e-66 222.5 0.0 7.5e-66 221.9 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 EKX50575.1 - 4e-55 186.4 1.4 6.9e-55 185.6 1.4 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 EKX50575.1 - 0.0023 17.7 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Tn7_Tnp_TnsA_C PF08721.11 EKX50576.1 - 0.026 15.2 1.0 78 4.0 0.0 3.3 1 1 4 5 5 5 0 TnsA endonuclease C terminal PA26 PF04636.13 EKX50576.1 - 0.14 11.1 0.0 63 2.3 0.0 3.0 1 1 4 5 5 5 0 PA26 p53-induced protein (sestrin) DAD PF02109.16 EKX50576.1 - 0.47 10.8 10.0 25 5.2 0.8 4.8 1 1 5 6 6 6 0 DAD family DUF5554 PF17709.1 EKX50576.1 - 2.4 8.3 17.2 48 4.2 1.5 5.5 1 1 4 5 5 5 0 Family of unknown function (DUF5554) ChaC PF04752.12 EKX50577.1 - 2.8e-34 118.7 2.3 5.4e-28 98.2 0.0 2.2 1 1 1 2 2 2 2 ChaC-like protein BT1 PF03092.16 EKX50578.1 - 7.3e-84 281.9 17.3 1.3e-48 165.6 7.4 2.0 1 1 1 2 2 2 2 BT1 family MFS_1 PF07690.16 EKX50578.1 - 1.3e-17 63.8 25.1 1.3e-17 63.8 25.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 EKX50578.1 - 0.00018 20.7 1.6 0.00077 18.6 1.6 2.0 1 1 0 1 1 1 1 PUCC protein EF-hand_7 PF13499.6 EKX50581.1 - 5.7e-32 110.0 8.2 1.2e-10 41.7 1.5 4.3 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 EKX50581.1 - 1.9e-31 105.2 6.0 3.5e-06 26.2 0.1 6.4 6 0 0 6 6 6 5 EF hand EF-hand_6 PF13405.6 EKX50581.1 - 8.9e-31 103.2 10.1 3.4e-06 26.5 0.3 6.4 6 0 0 6 6 6 5 EF-hand domain EF-hand_8 PF13833.6 EKX50581.1 - 4.6e-19 68.0 8.8 1.3e-05 24.9 0.4 5.8 4 1 1 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 EKX50581.1 - 4.5e-18 63.8 6.0 0.0056 16.1 0.0 5.6 5 0 0 5 5 5 5 EF hand SPARC_Ca_bdg PF10591.9 EKX50581.1 - 1.6e-08 34.9 4.4 0.06 13.7 0.1 4.3 3 1 0 4 4 4 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EKX50581.1 - 1.1e-06 28.5 6.2 0.03 14.3 0.1 4.0 3 1 1 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 EKX50581.1 - 0.0045 16.8 7.6 4.8 7.1 0.0 5.3 4 2 1 5 5 5 1 EF hand EF-hand_9 PF14658.6 EKX50581.1 - 0.0062 16.8 0.1 0.19 12.1 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain LMBR1 PF04791.16 EKX50582.1 - 0.00091 18.3 3.7 0.0013 17.8 3.7 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein Peptidase_S64 PF08192.11 EKX50582.1 - 1.2 7.5 14.6 1.7 7.0 14.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 OAD_gamma PF04277.13 EKX50582.1 - 6.8 7.4 7.8 23 5.6 0.1 2.7 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain FIST PF08495.10 EKX50583.1 - 0.16 12.0 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 FIST N domain PH PF00169.29 EKX50584.1 - 6.5e-05 23.4 0.4 0.00014 22.4 0.4 1.5 1 0 0 1 1 1 1 PH domain PTEN_C2 PF10409.9 EKX50584.1 - 0.00017 21.3 0.2 0.00031 20.5 0.2 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein PH_11 PF15413.6 EKX50584.1 - 0.00066 20.1 1.4 0.0017 18.7 1.4 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain cNMP_binding PF00027.29 EKX50584.1 - 0.0039 17.2 0.2 0.032 14.3 0.0 2.5 2 1 0 2 2 2 1 Cyclic nucleotide-binding domain DSPc PF00782.20 EKX50585.1 - 2.2e-05 24.3 0.0 3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EKX50585.1 - 3.4e-05 23.9 0.1 4.3e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EKX50585.1 - 0.00032 20.4 0.0 0.00034 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX50585.1 - 0.0016 18.5 0.0 0.0021 18.2 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.12 EKX50585.1 - 0.01 15.5 0.2 0.028 14.1 0.2 1.7 1 1 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Methyltransf_25 PF13649.6 EKX50586.1 - 7e-11 42.7 0.2 6.6e-10 39.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX50586.1 - 4.1e-10 40.2 0.1 1.6e-07 31.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX50586.1 - 6e-09 35.9 0.0 2e-08 34.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX50586.1 - 3.2e-05 24.6 0.0 9.9e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 EKX50586.1 - 0.00017 20.6 0.0 0.00024 20.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 EKX50586.1 - 0.00047 19.6 0.0 0.029 13.7 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EKX50586.1 - 0.00096 19.0 0.0 0.0024 17.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EKX50586.1 - 0.0089 16.0 0.0 0.012 15.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 EKX50586.1 - 0.025 14.2 0.0 0.069 12.8 0.0 1.6 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_4 PF02390.17 EKX50586.1 - 0.045 13.2 0.0 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase PrmA PF06325.13 EKX50586.1 - 0.13 11.6 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) NTP_transf_2 PF01909.23 EKX50587.1 - 1e-07 32.1 0.2 3.7e-07 30.3 0.0 2.1 2 1 0 2 2 2 1 Nucleotidyltransferase domain Polbeta PF18765.1 EKX50587.1 - 0.00048 20.2 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase CDRT4 PF15213.6 EKX50587.1 - 0.0059 17.2 0.1 0.0081 16.8 0.1 1.2 1 0 0 1 1 1 1 CMT1A duplicated region transcript 4 protein Eapp_C PF10238.9 EKX50587.1 - 0.039 14.0 0.2 0.059 13.4 0.2 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein Alpha_kinase PF02816.18 EKX50588.1 - 1.1e-37 130.0 0.7 1.2e-23 84.2 1.0 2.6 3 0 0 3 3 3 2 Alpha-kinase family zf-C3HC4_3 PF13920.6 EKX50588.1 - 5.9e-11 42.0 8.2 2.1e-10 40.3 8.2 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX50588.1 - 1.4e-06 28.0 9.8 4.1e-06 26.6 9.8 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EKX50588.1 - 2.6e-05 24.5 9.2 2.6e-05 24.5 9.2 2.9 2 0 0 2 2 2 1 Ring finger domain VWA_2 PF13519.6 EKX50588.1 - 0.0016 19.1 0.0 0.0037 17.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_5 PF14634.6 EKX50588.1 - 0.0019 18.1 8.9 0.0019 18.1 8.9 2.4 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EKX50588.1 - 0.023 14.5 8.7 0.069 13.0 8.7 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX50588.1 - 0.099 12.9 4.2 0.28 11.5 4.2 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EKX50588.1 - 0.12 12.5 8.0 0.41 10.9 8.0 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DZR PF12773.7 EKX50588.1 - 0.26 11.4 5.2 0.73 9.9 5.2 1.8 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_UBOX PF13445.6 EKX50588.1 - 0.49 10.5 5.9 0.83 9.7 3.4 2.6 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.6 EKX50588.1 - 5.6 6.8 8.6 0.43 10.4 3.2 2.0 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain Glyco_transf_49 PF13896.6 EKX50589.1 - 1.6e-25 90.2 0.0 5e-15 55.7 0.0 2.0 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan MYO10_CC PF16735.5 EKX50589.1 - 0.39 10.8 0.0 0.39 10.8 0.0 2.7 3 0 0 3 3 3 0 Unconventional myosin-X coiled coil domain FAM184 PF15665.5 EKX50590.1 - 0.14 11.9 2.9 0.057 13.2 0.7 1.4 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B DUF2203 PF09969.9 EKX50591.1 - 0.15 12.8 2.4 0.22 12.3 0.1 2.4 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Enkurin PF13864.6 EKX50591.1 - 2.4 8.6 7.9 7.6 7.0 0.1 2.8 3 1 0 3 3 3 0 Calmodulin-binding Cnd1 PF12717.7 EKX50592.1 - 2.8e-49 167.3 4.1 3.3e-44 150.8 0.0 4.6 2 2 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 EKX50592.1 - 4.1e-33 114.6 0.9 6.6e-32 110.6 0.0 2.6 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.22 EKX50592.1 - 4.5e-09 35.8 3.9 0.61 10.5 0.1 6.7 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 EKX50592.1 - 3.1e-06 27.5 2.8 0.013 15.9 0.0 5.2 4 2 1 5 5 5 2 HEAT repeats Adaptin_N PF01602.20 EKX50592.1 - 4.3e-05 22.3 10.4 0.00073 18.2 0.2 4.0 4 2 0 4 4 4 2 Adaptin N terminal region HEAT_EZ PF13513.6 EKX50592.1 - 0.0013 19.2 2.2 2 9.0 0.1 4.7 4 0 0 4 4 4 1 HEAT-like repeat Cohesin_HEAT PF12765.7 EKX50592.1 - 0.0063 16.8 0.1 0.06 13.7 0.1 2.8 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.7 EKX50592.1 - 0.021 14.1 0.8 0.12 11.6 0.0 2.7 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 EKX50592.1 - 0.036 14.2 8.5 16 5.7 0.6 5.4 4 2 3 7 7 7 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF4042 PF13251.6 EKX50592.1 - 0.08 12.6 9.4 0.22 11.2 0.2 3.9 5 0 0 5 5 5 0 Domain of unknown function (DUF4042) DUF2052 PF09747.9 EKX50592.1 - 0.71 10.0 10.4 2.8 8.0 0.7 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) RasGEF_N_2 PF14663.6 EKX50592.1 - 2.1 8.8 4.4 5.6 7.4 0.0 3.8 5 0 0 5 5 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain LMWPc PF01451.21 EKX50593.1 - 5e-08 33.4 0.0 1.9e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Trypan_PARP PF05887.11 EKX50594.1 - 3.1 7.8 47.1 6.2 6.8 27.7 2.0 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF4045 PF13254.6 EKX50594.1 - 3.5 7.2 38.3 4.2 6.9 38.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Pkinase PF00069.25 EKX50596.1 - 9.7e-34 116.9 2.9 5.1e-33 114.5 0.0 2.7 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX50596.1 - 1e-32 113.5 0.3 2e-32 112.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase SPECT1 PF18680.1 EKX50596.1 - 0.15 11.7 6.5 0.12 12.0 0.5 3.1 3 1 1 4 4 4 0 Plasmodium host cell traversal SPECT1 DUF4407 PF14362.6 EKX50596.1 - 0.8 9.0 4.0 1.2 8.4 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Prefoldin PF02996.17 EKX50596.1 - 6 6.8 9.4 5.6 6.9 0.8 2.4 2 0 0 2 2 2 0 Prefoldin subunit Spore_III_AF PF09581.10 EKX50601.1 - 0.018 15.1 1.2 0.028 14.5 1.2 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) TPT PF03151.16 EKX50602.1 - 1e-12 48.0 14.5 1.3e-12 47.7 14.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EKX50602.1 - 0.0015 18.7 22.8 0.0039 17.4 9.9 2.5 2 1 0 2 2 2 2 EamA-like transporter family RCC1 PF00415.18 EKX50604.1 - 2.6e-36 124.0 26.6 1.2e-08 35.4 0.1 6.9 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX50604.1 - 7.1e-26 89.4 21.6 1.9e-07 30.7 0.8 7.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Fn3_assoc PF13287.6 EKX50604.1 - 0.0016 18.5 0.1 0.0048 17.0 0.1 1.8 1 0 0 1 1 1 1 Fn3 associated CHB_HEX_C_1 PF13290.6 EKX50604.1 - 0.013 15.5 0.4 0.013 15.5 0.4 2.0 2 1 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain LPG_synthase_TM PF03706.13 EKX50604.1 - 0.019 14.5 0.1 0.03 13.8 0.1 1.2 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region DUF1459 PF07312.11 EKX50604.1 - 0.036 14.3 0.0 11 6.3 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1459) EphA2_TM PF14575.6 EKX50604.1 - 0.12 13.3 0.0 0.38 11.7 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 EKX50604.1 - 0.14 12.4 0.1 0.25 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) NICE-3 PF07406.11 EKX50604.1 - 0.25 11.3 0.5 0.47 10.4 0.5 1.4 1 0 0 1 1 1 0 NICE-3 protein Ion_trans_2 PF07885.16 EKX50605.1 - 0.16 12.0 7.6 0.17 11.9 5.1 2.4 2 1 0 2 2 2 0 Ion channel IQ PF00612.27 EKX50605.1 - 3.4 7.7 9.5 0.11 12.4 1.4 2.9 3 0 0 3 3 3 0 IQ calmodulin-binding motif PHD PF00628.29 EKX50606.1 - 6.6e-24 83.6 42.4 5.3e-12 45.4 12.7 3.9 2 1 2 4 4 4 3 PHD-finger PHD_2 PF13831.6 EKX50606.1 - 0.058 13.0 2.8 0.058 13.0 2.8 5.0 6 1 0 6 6 6 0 PHD-finger zf-RING_2 PF13639.6 EKX50606.1 - 0.064 13.6 4.2 0.064 13.6 4.2 4.6 2 1 2 4 4 4 0 Ring finger domain C1_1 PF00130.22 EKX50606.1 - 0.13 12.1 46.7 0.094 12.6 9.1 5.6 1 1 3 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_9 PF13901.6 EKX50606.1 - 2.1 8.3 32.0 4 7.4 1.7 3.2 2 1 1 3 3 3 0 Putative zinc-RING and/or ribbon zf-PHD-like PF15446.6 EKX50606.1 - 9.5 5.8 29.8 1.6 8.3 3.2 4.6 1 1 4 5 5 5 0 PHD/FYVE-zinc-finger like domain SET PF00856.28 EKX50607.1 - 3.8e-21 76.2 1.0 1.7e-20 74.1 1.0 1.9 1 1 0 1 1 1 1 SET domain WW PF00397.26 EKX50608.1 - 8.3e-05 22.6 1.9 0.39 10.9 0.1 3.6 2 0 0 2 2 2 2 WW domain Ribosomal_60s PF00428.19 EKX50608.1 - 0.016 15.8 7.9 0.039 14.5 7.9 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein TAFII55_N PF04658.13 EKX50608.1 - 1.3 8.7 4.7 20 4.9 0.1 2.4 2 0 0 2 2 2 0 TAFII55 protein conserved region EF-hand_1 PF00036.32 EKX50609.1 - 4.1e-24 82.3 12.2 2e-05 23.8 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EKX50609.1 - 1.7e-23 82.8 6.9 7.2e-13 48.8 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX50609.1 - 2.9e-21 73.5 11.4 1e-06 28.2 0.2 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EKX50609.1 - 3.2e-13 49.3 13.8 2.4e-09 36.9 0.4 3.5 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EKX50609.1 - 6.1e-13 47.6 14.0 0.00025 20.4 0.5 4.9 4 1 0 4 4 4 4 EF hand SPARC_Ca_bdg PF10591.9 EKX50609.1 - 7.6e-06 26.2 0.3 0.0047 17.2 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 EKX50609.1 - 1.4e-05 24.9 3.7 0.039 13.8 0.0 2.8 2 1 1 3 3 3 2 EF hand EF-hand_4 PF12763.7 EKX50609.1 - 0.00058 19.8 1.4 0.045 13.7 0.1 2.8 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand TerB PF05099.13 EKX50609.1 - 0.0029 17.6 0.0 0.19 11.7 0.0 2.0 2 0 0 2 2 2 1 Tellurite resistance protein TerB EF-hand_14 PF17959.1 EKX50609.1 - 0.023 15.0 0.3 0.27 11.6 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain VCBS PF13517.6 EKX50609.1 - 0.025 15.2 0.2 9.7 6.9 0.0 2.5 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_9 PF14658.6 EKX50609.1 - 0.026 14.9 0.1 0.44 10.9 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain p25-alpha PF05517.12 EKX50609.1 - 0.036 14.2 0.0 1.2 9.3 0.0 2.1 1 1 1 2 2 2 0 p25-alpha LEM PF03020.15 EKX50609.1 - 0.055 13.0 0.1 0.41 10.2 0.0 2.1 2 0 0 2 2 2 0 LEM domain Caleosin PF05042.13 EKX50609.1 - 0.11 12.4 0.1 6.1 6.7 0.0 2.7 1 1 2 3 3 3 0 Caleosin related protein VPS13_mid_rpt PF16910.5 EKX50609.1 - 0.12 11.8 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Repeating coiled region of VPS13 DUF2703 PF10865.8 EKX50609.1 - 0.13 12.4 0.1 0.45 10.7 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF2703) Pkinase PF00069.25 EKX50610.1 - 8.2e-41 140.1 0.0 1.5e-40 139.3 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX50610.1 - 3.2e-34 118.4 0.0 4.4e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX50610.1 - 2.5e-06 26.5 0.0 3.7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EKX50610.1 - 0.041 12.9 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 EKX50610.1 - 0.074 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family UCH PF00443.29 EKX50612.1 - 1.3e-51 175.6 0.2 1.6e-51 175.3 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EKX50612.1 - 1.1e-17 64.6 0.0 3e-17 63.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 EKX50612.1 - 6.3e-06 26.3 0.0 1.4e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 MATH domain DHHC PF01529.20 EKX50613.1 - 3.7e-05 23.8 2.9 3.7e-05 23.8 2.9 2.7 3 0 0 3 3 3 1 DHHC palmitoyltransferase Ank_2 PF12796.7 EKX50615.1 - 3.7e-14 53.1 0.0 4.5e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX50615.1 - 8e-12 45.4 0.0 9.2e-08 32.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX50615.1 - 1.1e-11 44.7 0.0 8.7e-06 25.9 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX50615.1 - 2.2e-11 42.9 0.0 0.0038 17.6 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 EKX50615.1 - 2.3e-11 43.6 0.0 0.0027 18.1 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EKX50616.1 - 1.6e-16 60.1 0.0 8.4e-07 29.2 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX50616.1 - 3.3e-16 59.6 0.0 4.4e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX50616.1 - 2.5e-14 53.4 0.0 1.4e-07 31.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX50616.1 - 8.3e-13 47.3 0.0 6.6e-06 26.1 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 EKX50616.1 - 1.5e-12 47.3 0.4 2.4e-05 24.6 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat zf-4CXXC_R1 PF10497.9 EKX50617.1 - 0.019 15.2 16.5 0.072 13.3 16.5 2.0 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 RRF PF01765.19 EKX50618.1 - 1.1e-59 201.1 2.8 1.1e-59 201.0 2.3 1.2 1 1 0 1 1 1 1 Ribosome recycling factor Vps53_N PF04100.12 EKX50618.1 - 0.0076 15.3 2.6 0.0098 14.9 2.6 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal YtxH PF12732.7 EKX50618.1 - 0.12 12.9 5.3 1.2 9.7 4.1 2.3 2 1 0 2 2 2 0 YtxH-like protein XhlA PF10779.9 EKX50618.1 - 0.77 10.0 5.3 0.35 11.1 1.1 2.4 2 1 0 2 2 2 0 Haemolysin XhlA ECH_1 PF00378.20 EKX50619.1 - 1e-48 165.9 0.0 1.2e-48 165.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EKX50619.1 - 2.3e-18 66.8 0.0 2.5e-18 66.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase TRAM_LAG1_CLN8 PF03798.16 EKX50620.1 - 2.6e-19 69.7 20.9 4.2e-19 69.1 20.9 1.3 1 0 0 1 1 1 1 TLC domain Keratin_assoc PF09775.9 EKX50620.1 - 0.21 11.2 3.4 0.14 11.8 0.4 2.2 2 0 0 2 2 2 0 Keratinocyte-associated protein 2 Arm PF00514.23 EKX50622.1 - 2.5e-09 36.8 20.3 0.15 12.2 0.1 8.4 9 0 0 9 9 9 5 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EKX50622.1 - 0.001 19.0 4.3 1.3 9.0 0.0 4.9 4 1 1 5 5 5 2 Spinocerebellar ataxia type 10 protein domain HLH PF00010.26 EKX50624.1 - 8.9e-17 60.8 4.9 2e-08 34.0 0.8 2.4 2 0 0 2 2 2 2 Helix-loop-helix DNA-binding domain DUF3140 PF11338.8 EKX50625.1 - 0.093 13.2 0.5 0.24 11.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3140) Dickkopf_N PF04706.12 EKX50626.1 - 0.26 11.8 14.8 0.44 11.1 14.8 1.4 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region SNF2_N PF00176.23 EKX50630.1 - 2.8e-69 233.5 0.5 2.8e-69 233.5 0.5 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX50630.1 - 3.5e-16 59.5 0.1 2.7e-15 56.7 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX50630.1 - 5.3e-09 36.3 0.0 1.4e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EKX50630.1 - 9e-06 25.1 0.7 0.00025 20.3 0.7 2.4 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 CLTH PF10607.9 EKX50631.1 - 1.8e-19 70.1 0.1 2.4e-19 69.7 0.1 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain BBS2_Mid PF14783.6 EKX50632.1 - 0.00022 21.2 0.0 0.0019 18.2 0.0 2.6 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region PHTB1_N PF14727.6 EKX50632.1 - 0.024 14.0 3.7 0.064 12.6 0.1 2.6 3 0 0 3 3 3 0 PTHB1 N-terminus PspA_IM30 PF04012.12 EKX50632.1 - 0.58 9.7 11.6 0.24 11.0 2.4 2.2 2 0 0 2 2 2 0 PspA/IM30 family RWP-RK PF02042.15 EKX50634.1 - 6.8e-19 67.6 0.1 1.6e-18 66.4 0.1 1.7 1 0 0 1 1 1 1 RWP-RK domain SNF2_N PF00176.23 EKX50636.1 - 1.3e-52 178.7 0.0 2.1e-52 178.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX50636.1 - 1.1e-11 45.1 0.0 4.5e-11 43.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PHD PF00628.29 EKX50636.1 - 9.5e-06 25.4 10.0 9.5e-06 25.4 10.0 3.1 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.6 EKX50636.1 - 0.00082 18.9 4.7 0.00082 18.9 4.7 2.6 2 1 0 2 2 2 1 PHD-finger Kelch_1 PF01344.25 EKX50637.1 - 1.5e-17 62.9 0.1 1.5e-07 30.9 0.1 2.7 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 EKX50637.1 - 9.1e-10 38.5 0.0 0.0019 18.4 0.0 2.4 1 1 1 2 2 2 2 Kelch motif zf-C2H2 PF00096.26 EKX50637.1 - 0.00041 20.7 0.5 0.00072 19.9 0.5 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type Kelch_4 PF13418.6 EKX50637.1 - 0.0017 18.3 0.0 2.9 8.0 0.0 2.5 2 0 0 2 2 2 2 Galactose oxidase, central domain zf-C2H2_4 PF13894.6 EKX50637.1 - 0.0019 18.9 0.4 0.0037 18.0 0.4 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EKX50637.1 - 0.004 17.1 0.2 0.006 16.6 0.2 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger TFIIE-A_C PF11521.8 EKX50637.1 - 0.01 16.1 2.2 0.86 10.0 0.1 2.6 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha RNA_POL_M_15KD PF02150.16 EKX50637.1 - 0.019 14.8 0.1 0.04 13.8 0.1 1.6 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit Kelch_5 PF13854.6 EKX50637.1 - 0.025 14.6 0.0 2.4 8.3 0.1 2.6 2 0 0 2 2 2 0 Kelch motif Kelch_2 PF07646.15 EKX50637.1 - 0.044 13.8 0.8 11 6.1 0.1 2.7 2 1 0 2 2 2 0 Kelch motif DUF3246 PF11596.8 EKX50637.1 - 0.19 11.1 9.8 0.057 12.9 6.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) LAT PF15234.6 EKX50637.1 - 1.4 8.6 7.2 0.095 12.4 1.5 1.9 2 0 0 2 2 2 0 Linker for activation of T-cells DUF3136 PF11334.8 EKX50638.1 - 0.012 15.4 0.3 0.092 12.5 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3136) CREPT PF16566.5 EKX50639.1 - 0.1 12.8 10.0 0.24 11.5 10.0 1.6 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DUF244 PF03112.14 EKX50639.1 - 0.17 11.7 2.9 2.5 7.9 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein family (ORF7) DUF DivIC PF04977.15 EKX50639.1 - 2.4 8.0 12.4 0.46 10.3 4.4 2.6 1 1 1 2 2 2 0 Septum formation initiator YabA PF06156.13 EKX50639.1 - 5 7.8 14.8 9.7 6.9 10.3 3.0 2 1 1 3 3 3 0 Initiation control protein YabA TMPIT PF07851.13 EKX50639.1 - 5.8 6.1 9.2 11 5.1 9.2 1.4 1 0 0 1 1 1 0 TMPIT-like protein Sigma70_ner PF04546.13 EKX50639.1 - 7.7 6.3 19.3 51 3.7 19.0 2.2 1 1 0 1 1 1 0 Sigma-70, non-essential region Lipase_GDSL_2 PF13472.6 EKX50640.1 - 1.9e-26 93.5 0.0 2.3e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EKX50640.1 - 4.6e-20 72.5 0.0 7.9e-20 71.7 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Rubis-subs-bind PF09273.11 EKX50641.1 - 3.1e-06 27.9 0.6 3.8e-05 24.4 0.1 2.4 2 1 0 2 2 2 1 Rubisco LSMT substrate-binding ARS2 PF04959.13 EKX50642.1 - 0.00015 22.2 0.9 0.0002 21.8 0.3 1.5 1 1 0 1 1 1 1 Arsenite-resistance protein 2 Glyco_tranf_2_4 PF13704.6 EKX50642.1 - 0.1 13.1 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF4709 PF15821.5 EKX50642.1 - 0.12 12.7 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4709) CMAS PF02353.20 EKX50643.1 - 0.019 14.3 0.0 0.023 14.0 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Glu_syn_central PF04898.14 EKX50643.1 - 0.23 10.9 1.2 0.29 10.6 1.2 1.1 1 0 0 1 1 1 0 Glutamate synthase central domain PBP1_TM PF14812.6 EKX50643.1 - 3.4 8.1 10.8 0.48 10.8 5.6 2.1 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.25 EKX50644.1 - 2.2e-74 250.2 0.0 3.3e-74 249.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX50644.1 - 1.8e-45 155.3 0.0 2.9e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX50644.1 - 4.4e-11 42.6 0.0 1e-10 41.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EKX50644.1 - 0.00022 20.3 0.5 0.00044 19.3 0.2 1.5 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EKX50644.1 - 0.0023 17.9 0.5 0.0051 16.8 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX50644.1 - 0.0035 16.7 0.4 0.016 14.6 0.2 2.2 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EKX50644.1 - 0.027 13.5 0.1 0.053 12.6 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 UPF0564 PF10595.9 EKX50644.1 - 0.14 11.2 9.7 0.36 9.8 9.7 1.8 1 1 0 1 1 1 0 Uncharacterised protein family UPF0564 Pkinase_fungal PF17667.1 EKX50644.1 - 2 7.1 8.1 0.28 9.9 3.4 1.9 2 1 0 2 2 2 0 Fungal protein kinase PDZ_6 PF17820.1 EKX50645.1 - 2.2e-10 40.2 0.1 3.3e-10 39.7 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX50645.1 - 1.4e-08 35.0 0.0 2.2e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX50645.1 - 2.3e-05 24.7 0.0 3.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX50645.1 - 0.0054 16.7 0.1 0.0086 16.0 0.1 1.3 1 0 0 1 1 1 1 Tricorn protease PDZ domain Pkinase PF00069.25 EKX50646.1 - 5.9e-08 32.4 0.0 0.0021 17.5 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain EF-hand_7 PF13499.6 EKX50646.1 - 0.00012 22.5 0.8 0.01 16.3 0.2 3.1 2 0 0 2 2 2 1 EF-hand domain pair Pkinase_Tyr PF07714.17 EKX50646.1 - 0.0026 17.1 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase EF-hand_8 PF13833.6 EKX50646.1 - 0.0078 16.0 0.3 0.085 12.7 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX50646.1 - 0.036 13.6 0.3 0.26 10.9 0.1 2.7 2 0 0 2 2 2 0 EF hand Cgr1 PF03879.14 EKX50646.1 - 0.047 14.1 2.1 0.16 12.3 2.1 1.9 1 0 0 1 1 1 0 Cgr1 family PPR_3 PF13812.6 EKX50647.1 - 1.4e-55 185.2 3.3 1.8e-11 43.9 0.1 8.6 5 3 3 8 8 8 8 Pentatricopeptide repeat domain PPR_2 PF13041.6 EKX50647.1 - 6.1e-52 173.6 11.2 2.3e-08 34.1 0.0 10.1 8 3 3 11 11 11 9 PPR repeat family PPR_long PF17177.4 EKX50647.1 - 6.8e-31 107.3 0.0 1.4e-10 41.0 0.0 4.3 1 1 3 4 4 4 4 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EKX50647.1 - 1.4e-28 98.2 39.5 4.6e-05 23.0 0.0 12.8 12 2 0 12 12 12 8 PPR repeat PPR PF01535.20 EKX50647.1 - 9.9e-17 60.0 47.2 4.5e-06 26.5 0.0 15.3 16 2 1 17 17 17 4 PPR repeat ECSIT PF06239.11 EKX50647.1 - 1.7e-12 46.9 0.1 0.062 12.4 0.0 7.0 3 2 3 6 6 6 4 Evolutionarily conserved signalling intermediate in Toll pathway BTAD PF03704.17 EKX50647.1 - 0.00055 20.4 0.0 0.0013 19.2 0.0 1.6 1 0 0 1 1 1 1 Bacterial transcriptional activator domain GMP_synt_C PF00958.22 EKX50647.1 - 0.0046 17.0 0.0 3.3 7.8 0.0 3.0 2 1 0 2 2 2 2 GMP synthase C terminal domain Exog_C PF18026.1 EKX50647.1 - 0.012 15.6 0.2 4.7 7.4 0.0 4.7 6 0 0 6 6 6 0 Endo/exonuclease (EXOG) C-terminal domain DUF884 PF05959.11 EKX50647.1 - 0.076 12.6 0.5 48 3.5 0.0 4.1 2 2 2 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF884) SesA PF17107.5 EKX50647.1 - 0.21 11.8 0.6 2.4 8.3 0.1 2.9 3 1 1 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Ank_2 PF12796.7 EKX50648.1 - 9.9e-24 83.7 0.1 7.8e-06 26.4 0.0 5.7 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX50648.1 - 1.2e-11 43.7 0.5 0.88 10.3 0.0 8.4 8 0 0 8 8 8 2 Ankyrin repeat Ank_5 PF13857.6 EKX50648.1 - 7.9e-09 35.6 1.4 0.59 10.5 0.0 6.8 7 1 0 7 7 7 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX50648.1 - 1.5e-08 34.7 0.8 8.3 7.1 0.0 6.6 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.6 EKX50648.1 - 1.6e-08 34.9 4.9 0.034 14.7 0.0 6.5 4 2 2 6 6 6 2 Ankyrin repeats (many copies) YL1 PF05764.13 EKX50648.1 - 0.00025 21.2 22.6 0.00025 21.2 22.6 2.5 2 0 0 2 2 2 1 YL1 nuclear protein PI3K_1B_p101 PF10486.9 EKX50648.1 - 0.32 8.7 3.4 1.2 6.8 3.2 1.9 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SOBP PF15279.6 EKX50648.1 - 0.38 11.3 10.6 1.1 9.8 10.6 1.8 1 0 0 1 1 1 0 Sine oculis-binding protein SAPS PF04499.15 EKX50648.1 - 2.5 6.8 17.3 0.012 14.4 8.1 1.6 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein DUF3481 PF11980.8 EKX50649.1 - 0.14 11.8 0.8 11 5.8 0.1 2.4 2 0 0 2 2 2 0 C-terminal domain of neuropilin glycoprotein GFO_IDH_MocA PF01408.22 EKX50650.1 - 4.5e-20 72.7 0.0 1e-19 71.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EKX50650.1 - 7.1e-05 22.8 0.0 0.00019 21.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.24 EKX50650.1 - 0.0042 17.5 0.0 0.05 14.0 0.0 2.4 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 EKX50650.1 - 0.035 14.2 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 EKX50650.1 - 0.073 13.4 0.0 0.43 10.9 0.0 2.1 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EKX50650.1 - 0.09 13.0 0.1 0.34 11.2 0.1 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ABC1 PF03109.16 EKX50651.1 - 9.9e-21 74.1 0.0 1.8e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EKX50651.1 - 0.0055 16.7 0.5 0.014 15.4 0.5 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EKX50651.1 - 0.011 15.4 0.0 0.031 13.9 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Mo25 PF08569.11 EKX50652.1 - 7e-92 308.3 8.5 8.4e-92 308.0 8.5 1.0 1 0 0 1 1 1 1 Mo25-like ZapB PF06005.12 EKX50652.1 - 0.27 11.7 6.6 5.1 7.6 1.0 2.5 2 0 0 2 2 2 0 Cell division protein ZapB VPR PF00522.18 EKX50653.1 - 0.1 12.6 0.9 0.22 11.6 0.1 2.0 2 0 0 2 2 2 0 VPR/VPX protein PTPS_related PF10131.9 EKX50653.1 - 9.7 4.4 17.7 0.11 10.9 3.9 2.8 3 0 0 3 3 3 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein GFA PF04828.14 EKX50654.1 - 2.3e-10 40.7 4.1 1.1e-08 35.2 4.1 2.4 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme C2 PF00168.30 EKX50658.1 - 4.3e-18 65.5 0.0 6e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 C2 domain DUF4497 PF14924.6 EKX50658.1 - 0.041 14.4 0.0 0.081 13.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4497) 6PF2K PF01591.18 EKX50659.1 - 7.7e-73 244.5 0.0 1.1e-72 244.0 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EKX50659.1 - 6e-34 117.4 0.1 9.3e-34 116.8 0.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EKX50659.1 - 6.7e-08 32.8 0.0 1.5e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EKX50659.1 - 0.0051 16.3 0.0 0.0077 15.7 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 EKX50659.1 - 0.11 13.0 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EKX50659.1 - 0.13 12.0 0.0 45 3.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain Guanylate_cyc PF00211.20 EKX50660.1 - 1.6e-51 174.6 0.0 2.1e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain AAA PF00004.29 EKX50661.1 - 1.2e-37 129.3 0.0 1.5e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EKX50661.1 - 1.6e-06 27.9 0.0 4.4e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EKX50661.1 - 5.2e-06 26.5 0.2 4.3e-05 23.5 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EKX50661.1 - 0.00033 21.1 0.0 0.033 14.6 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 EKX50661.1 - 0.0004 20.5 0.0 0.00064 19.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 EKX50661.1 - 0.00066 19.0 0.0 0.0011 18.2 0.0 1.3 1 1 0 1 1 1 1 TIP49 P-loop domain Sigma54_activat PF00158.26 EKX50661.1 - 0.0016 18.1 0.0 0.084 12.6 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain DUF815 PF05673.13 EKX50661.1 - 0.002 17.3 0.0 0.0025 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 EKX50661.1 - 0.0021 18.6 0.0 0.0032 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 EKX50661.1 - 0.0022 17.4 0.0 2.4 7.5 0.0 2.4 1 1 1 2 2 2 2 Bacterial TniB protein AAA_33 PF13671.6 EKX50661.1 - 0.0024 18.1 0.0 0.0077 16.4 0.0 1.7 1 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EKX50661.1 - 0.0025 17.8 0.0 0.0035 17.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EKX50661.1 - 0.0053 17.0 0.1 0.045 14.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EKX50661.1 - 0.0063 15.9 0.1 0.019 14.4 0.1 1.7 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EKX50661.1 - 0.0077 16.0 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EKX50661.1 - 0.012 15.9 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 EKX50661.1 - 0.02 14.5 0.1 0.21 11.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.6 EKX50661.1 - 0.032 14.6 0.0 0.15 12.5 0.0 2.0 1 1 1 2 2 2 0 AAA domain TsaE PF02367.17 EKX50661.1 - 0.042 13.9 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EKX50661.1 - 0.055 13.4 0.0 0.28 11.1 0.0 2.0 1 1 1 2 2 2 0 NACHT domain AAA_7 PF12775.7 EKX50661.1 - 0.069 12.7 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_3 PF07726.11 EKX50661.1 - 0.07 13.0 0.0 0.086 12.7 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EKX50661.1 - 0.13 11.6 0.0 2.2 7.6 0.0 2.0 1 1 1 2 2 2 0 KaiC PhoH PF02562.16 EKX50661.1 - 0.16 11.4 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activ_2 PF14532.6 EKX50661.1 - 0.16 12.0 0.0 0.58 10.3 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 EKX50661.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain CBS PF00571.28 EKX50662.1 - 0.01 16.3 0.1 0.047 14.1 0.0 2.0 2 0 0 2 2 2 0 CBS domain Voltage_CLC PF00654.20 EKX50663.1 - 3.8e-77 259.9 30.0 4.8e-77 259.6 30.0 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 EKX50663.1 - 0.001 19.4 1.0 0.0044 17.4 0.2 2.3 2 0 0 2 2 2 1 CBS domain TAT_signal PF10518.9 EKX50663.1 - 0.013 15.3 2.4 0.013 15.3 2.4 3.9 4 0 0 4 4 4 0 TAT (twin-arginine translocation) pathway signal sequence fn3 PF00041.21 EKX50664.1 - 3e-05 24.3 0.1 0.047 14.1 0.0 4.0 4 0 0 4 4 4 1 Fibronectin type III domain Laminin_G_3 PF13385.6 EKX50664.1 - 0.012 15.8 0.0 0.17 12.0 0.0 2.4 1 1 1 2 2 2 0 Concanavalin A-like lectin/glucanases superfamily DUF5549 PF17703.1 EKX50664.1 - 0.11 12.1 2.5 0.26 10.9 2.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5549) Smg8_Smg9 PF10220.9 EKX50665.1 - 2e-25 89.3 9.1 2.3e-23 82.5 1.3 2.4 3 0 0 3 3 3 2 Smg8_Smg9 ASFV_L11L PF05293.11 EKX50665.1 - 0.23 11.8 0.1 0.54 10.6 0.1 1.5 1 0 0 1 1 1 0 African swine fever virus (ASFV) L11L protein DUF3287 PF11690.8 EKX50666.1 - 0.085 12.6 0.8 0.22 11.2 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) FliT PF05400.13 EKX50666.1 - 0.13 13.1 2.5 0.36 11.7 1.6 2.3 2 0 0 2 2 2 0 Flagellar protein FliT zf-C4H2 PF10146.9 EKX50667.1 - 0.0037 17.6 3.5 0.0061 16.9 3.5 1.4 1 0 0 1 1 1 1 Zinc finger-containing protein DUF724 PF05266.14 EKX50667.1 - 0.046 13.5 18.6 0.13 12.1 18.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF724) BLOC1_2 PF10046.9 EKX50667.1 - 0.055 13.8 11.8 0.56 10.5 7.3 2.5 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V_ATPase_I PF01496.19 EKX50667.1 - 0.23 9.4 14.6 0.29 9.0 14.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MAD PF05557.13 EKX50667.1 - 0.35 9.2 25.6 0.54 8.6 25.6 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein Spc7 PF08317.11 EKX50667.1 - 0.38 9.6 21.5 0.61 8.9 21.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1192 PF06698.11 EKX50667.1 - 0.43 10.7 9.0 1.5 9.0 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Med9 PF07544.13 EKX50667.1 - 0.55 10.4 13.9 0.79 9.8 2.5 3.3 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 ADIP PF11559.8 EKX50667.1 - 0.8 9.8 25.5 2.6 8.1 3.6 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.12 EKX50667.1 - 1 9.4 28.7 2.9 7.9 28.6 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein SpecificRecomb PF10136.9 EKX50667.1 - 2.1 6.6 7.0 3.1 6.0 7.0 1.1 1 0 0 1 1 1 0 Site-specific recombinase Allexi_40kDa PF05549.11 EKX50667.1 - 2.3 7.7 9.4 0.39 10.2 3.4 2.0 1 1 2 3 3 3 0 Allexivirus 40kDa protein CENP-F_leu_zip PF10473.9 EKX50667.1 - 2.8 7.9 25.4 4.2 7.4 24.6 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF16 PF01519.16 EKX50667.1 - 3 8.4 15.8 2.9 8.4 5.9 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 BRE1 PF08647.11 EKX50667.1 - 3.1 7.9 22.9 0.57 10.3 10.1 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Exonuc_VII_L PF02601.15 EKX50667.1 - 3.8 7.0 14.8 6 6.4 14.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 EKX50667.1 - 4.1 7.4 11.7 0.5 10.4 3.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Prominin PF05478.11 EKX50667.1 - 4.9 5.0 9.6 6.6 4.6 9.6 1.1 1 0 0 1 1 1 0 Prominin Tropomyosin_1 PF12718.7 EKX50667.1 - 5.5 7.1 28.9 3.8 7.6 20.7 2.7 1 1 1 2 2 2 0 Tropomyosin like TMCO5 PF14992.6 EKX50667.1 - 6.9 6.2 16.0 10 5.6 16.0 1.2 1 0 0 1 1 1 0 TMCO5 family GAS PF13851.6 EKX50667.1 - 9.8 5.5 28.7 3.8 6.8 16.6 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding LRR_6 PF13516.6 EKX50668.1 - 1.5e-06 27.8 0.1 0.16 12.1 0.0 3.8 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.7 EKX50668.1 - 0.0089 16.4 0.7 3.2 8.3 0.0 3.2 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) DUF4451 PF14616.6 EKX50668.1 - 0.19 11.9 0.0 0.33 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) Atx10homo_assoc PF09759.9 EKX50670.1 - 9e-09 35.3 1.0 0.0036 17.3 0.1 5.0 3 1 2 5 5 5 3 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 EKX50670.1 - 0.075 12.5 1.7 0.13 11.7 0.1 2.1 3 0 0 3 3 3 0 Armadillo-like XRN_N PF03159.18 EKX50671.1 - 2.5e-31 109.0 0.0 9.5e-20 71.0 0.0 2.2 1 1 1 2 2 2 2 XRN 5'-3' exonuclease N-terminus Pkinase PF00069.25 EKX50673.1 - 6.8e-42 143.6 0.0 8.7e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX50673.1 - 1.8e-32 112.7 0.0 2.4e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX50673.1 - 0.083 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EKX50673.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FGAR-AT_N PF18076.1 EKX50673.1 - 0.16 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase N-terminal PDEase_I PF00233.19 EKX50674.1 - 3.5e-66 223.3 0.0 4.2e-66 223.1 0.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Guanylate_cyc PF00211.20 EKX50675.1 - 4.5e-09 36.2 0.1 5e-09 36.0 0.1 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Phycoerythr_ab PF02972.14 EKX50677.1 - 6.5e-29 99.5 0.0 1.1e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Phycoerythrin, alpha/beta chain Zip PF02535.22 EKX50678.1 - 1.2e-12 47.7 16.0 1.7e-12 47.2 7.0 2.3 2 0 0 2 2 2 2 ZIP Zinc transporter Hpt PF01627.23 EKX50678.1 - 0.22 11.8 0.4 0.4 11.0 0.4 1.4 1 0 0 1 1 1 0 Hpt domain AAA PF00004.29 EKX50679.1 - 1.1e-51 174.7 0.0 3.3e-38 131.1 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EKX50679.1 - 9.9e-14 50.9 1.1 1.7e-09 37.3 0.1 2.5 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 EKX50679.1 - 2.3e-07 30.9 0.1 9.2e-07 29.0 0.0 2.1 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 EKX50679.1 - 6e-05 23.2 0.0 0.00013 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EKX50679.1 - 0.00094 19.6 0.1 0.0054 17.1 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EKX50679.1 - 0.001 19.3 0.2 0.054 13.8 0.2 2.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EKX50679.1 - 0.0015 18.3 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EKX50679.1 - 0.0025 18.4 0.0 0.0048 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EKX50679.1 - 0.0078 16.2 0.1 0.029 14.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EKX50679.1 - 0.011 15.9 0.0 0.018 15.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EKX50679.1 - 0.016 14.8 0.2 0.83 9.2 0.0 2.5 1 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EKX50679.1 - 0.027 13.9 0.1 0.055 12.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Molydop_binding PF01568.21 EKX50679.1 - 0.03 14.3 0.0 0.073 13.1 0.0 1.6 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain Rad17 PF03215.15 EKX50679.1 - 0.046 13.6 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain RNA_helicase PF00910.22 EKX50679.1 - 0.048 14.1 0.0 0.096 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 EKX50679.1 - 0.053 12.7 0.0 0.084 12.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 EKX50679.1 - 0.071 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EKX50679.1 - 0.14 12.0 0.3 5 7.0 0.0 2.2 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 EKX50680.1 - 0.058 13.5 0.0 0.15 12.1 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 EKX50680.1 - 0.091 13.1 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 EKX50680.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family UCH PF00443.29 EKX50681.1 - 9.7e-41 140.0 0.1 1.5e-40 139.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EKX50681.1 - 2.2e-09 37.4 3.1 2e-08 34.2 3.1 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EKX50681.1 - 0.057 13.2 0.1 0.41 10.4 0.0 2.6 2 1 0 2 2 2 0 Ubiquitin family RNA_pol_3_Rpc31 PF11705.8 EKX50681.1 - 0.099 12.9 15.7 0.067 13.4 6.7 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Thioredoxin_8 PF13905.6 EKX50682.1 - 2.8e-08 34.0 0.0 3.3e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like DUF3598 PF12204.8 EKX50683.1 - 3.5e-10 39.8 0.0 0.0019 17.8 0.0 3.9 2 1 0 2 2 2 2 Domain of unknown function (DUF3598) HTH_15 PF12324.8 EKX50683.1 - 0.044 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase Ribosomal_S17 PF00366.20 EKX50684.1 - 4.9e-23 81.0 4.1 8.9e-23 80.2 3.8 1.6 2 0 0 2 2 2 1 Ribosomal protein S17 CoA_binding PF02629.19 EKX50685.1 - 1e-31 109.5 2.4 5.8e-31 107.0 0.2 2.5 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EKX50685.1 - 6.2e-21 74.8 0.1 9.7e-21 74.2 0.1 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EKX50685.1 - 2.1e-09 37.3 0.3 3.9e-09 36.4 0.0 1.5 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EKX50685.1 - 6.8e-05 23.3 0.0 0.00018 22.0 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain Pkinase PF00069.25 EKX50687.1 - 5.6e-25 88.2 0.0 7e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX50687.1 - 1.7e-12 47.2 0.0 2.4e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX50687.1 - 6.5e-08 31.8 0.1 8.8e-08 31.3 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EKX50687.1 - 0.0002 20.8 0.0 0.00037 19.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX50687.1 - 0.0087 16.0 0.1 0.02 14.9 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EKX50687.1 - 0.02 14.2 0.0 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.22 EKX50687.1 - 0.023 14.3 0.1 0.047 13.3 0.1 1.4 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 EKX50687.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 SLX9 PF15341.6 EKX50688.1 - 2.2e-11 44.3 0.6 2.2e-11 44.3 0.6 1.8 1 1 1 2 2 2 1 Ribosome biogenesis protein SLX9 ChuX_HutX PF06228.13 EKX50689.1 - 0.029 14.2 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 Haem utilisation ChuX/HutX DUF5582 PF17819.1 EKX50690.1 - 0.12 12.8 1.2 0.32 11.5 1.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5582) RAP PF08373.10 EKX50692.1 - 1e-20 73.6 0.1 1.5e-20 73.0 0.1 1.3 1 0 0 1 1 1 1 RAP domain Baculo_PEP_C PF04513.12 EKX50693.1 - 0.00087 19.3 1.9 0.88 9.6 0.3 3.2 3 1 0 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus SKA2 PF16740.5 EKX50693.1 - 0.0059 16.4 1.8 0.0059 16.4 1.8 4.1 3 1 0 3 3 3 1 Spindle and kinetochore-associated protein 2 TPR_MLP1_2 PF07926.12 EKX50693.1 - 0.013 15.5 6.6 0.013 15.5 6.6 6.6 5 1 2 7 7 7 0 TPR/MLP1/MLP2-like protein DUF948 PF06103.11 EKX50693.1 - 0.015 15.5 0.3 0.015 15.5 0.3 3.8 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Med9 PF07544.13 EKX50693.1 - 0.015 15.3 2.9 0.015 15.3 2.9 5.0 6 0 0 6 6 6 0 RNA polymerase II transcription mediator complex subunit 9 DUF3502 PF12010.8 EKX50693.1 - 0.053 14.2 0.5 0.053 14.2 0.5 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3502) Bacillus_HBL PF05791.11 EKX50693.1 - 1.8 8.3 10.8 0.14 12.0 0.9 3.2 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) NPV_P10 PF05531.12 EKX50693.1 - 1.9 9.0 10.1 0.094 13.2 1.2 3.4 4 1 0 4 4 3 0 Nucleopolyhedrovirus P10 protein LXG PF04740.12 EKX50693.1 - 3.6 7.3 19.1 0.047 13.4 1.5 4.0 4 1 1 5 5 5 0 LXG domain of WXG superfamily LPP PF04728.13 EKX50693.1 - 5.3 7.5 12.6 0.65 10.4 1.8 4.3 4 1 0 5 5 5 0 Lipoprotein leucine-zipper TMPIT PF07851.13 EKX50693.1 - 5.6 6.1 31.9 0.6 9.3 3.3 4.7 2 1 2 4 4 4 0 TMPIT-like protein DDE_Tnp_4 PF13359.6 EKX50695.1 - 2.6e-08 33.7 0.0 3e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease E7 PF00527.18 EKX50696.1 - 0.31 11.3 4.1 0.3 11.3 0.9 2.3 1 1 1 2 2 2 0 E7 protein, Early protein WD40 PF00400.32 EKX50697.1 - 2.2e-13 50.4 8.0 8.8e-06 26.4 0.2 5.6 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX50697.1 - 0.00033 20.9 0.0 3.4 8.0 0.0 3.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain NHL PF01436.21 EKX50698.1 - 0.089 12.9 0.4 12 6.2 0.0 3.3 3 0 0 3 3 3 0 NHL repeat TBCA PF02970.16 EKX50700.1 - 3e-24 85.1 4.5 3.6e-24 84.9 4.5 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A DUF5082 PF16888.5 EKX50700.1 - 0.001 19.3 3.4 0.024 14.9 0.1 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF5082) DUF724 PF05266.14 EKX50700.1 - 0.18 11.6 2.8 0.22 11.3 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4407 PF14362.6 EKX50700.1 - 0.7 9.2 5.2 0.72 9.1 5.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_12 PF13424.6 EKX50702.1 - 9.4e-14 51.5 6.9 7.5e-06 26.2 0.2 4.1 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX50702.1 - 6.3e-06 25.9 4.6 1 9.3 0.1 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX50702.1 - 0.0088 16.8 0.5 9.1 7.4 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX50702.1 - 0.011 15.7 10.6 0.38 11.0 0.8 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX50702.1 - 0.025 15.1 4.7 10 6.7 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EKX50702.1 - 0.044 13.6 7.0 3.7 7.5 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DotD PF16816.5 EKX50702.1 - 0.084 12.8 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 DotD protein TPR_4 PF07721.14 EKX50702.1 - 0.1 13.3 0.5 9.5 7.2 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX50702.1 - 0.12 12.6 9.6 0.4 11.0 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX50702.1 - 1.8 9.3 6.9 86 4.1 1.6 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX50702.1 - 3.8 7.8 6.2 35 4.7 0.1 3.4 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EKX50702.1 - 4.1 8.1 6.9 11 6.7 0.7 3.8 3 2 0 3 3 3 0 Tetratricopeptide repeat FNIP PF05725.12 EKX50703.1 - 0.056 13.6 0.0 0.95 9.7 0.0 2.4 2 0 0 2 2 2 0 FNIP Repeat ICAT PF06384.11 EKX50704.1 - 4.1e-16 59.0 2.7 4.1e-16 59.0 2.7 2.1 2 0 0 2 2 2 1 Beta-catenin-interacting protein ICAT CAMP_factor PF07373.11 EKX50704.1 - 0.088 12.4 4.1 0.24 11.0 3.8 1.8 1 1 0 1 1 1 0 CAMP factor (Cfa) Goodbye PF17109.5 EKX50704.1 - 0.12 12.8 2.1 2.7 8.4 0.1 2.2 1 1 1 2 2 2 0 fungal STAND N-terminal Goodbye domain DUF3417 PF11897.8 EKX50704.1 - 0.15 12.5 2.1 0.66 10.5 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3417) SLED PF12140.8 EKX50704.1 - 0.24 11.9 1.3 0.94 10.0 0.3 2.2 2 1 0 2 2 2 0 SLED domain FUSC PF04632.12 EKX50704.1 - 0.99 7.9 5.3 1.3 7.5 5.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family GvpG PF05120.12 EKX50704.1 - 1.2 9.2 19.3 1.4 8.9 4.8 2.7 2 1 1 3 3 3 0 Gas vesicle protein G CSTF2_hinge PF14327.6 EKX50704.1 - 1.3 9.5 6.6 0.76 10.3 0.9 2.8 3 0 0 3 3 3 0 Hinge domain of cleavage stimulation factor subunit 2 PARP_reg PF02877.14 EKX50705.1 - 0.0079 16.3 2.3 0.0079 16.3 2.3 2.7 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain DUF4407 PF14362.6 EKX50705.1 - 0.0083 15.5 3.5 0.0083 15.5 3.5 3.6 3 2 0 3 3 3 1 Domain of unknown function (DUF4407) Ribosomal_60s PF00428.19 EKX50705.1 - 0.023 15.3 6.2 0.089 13.4 6.2 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein FlaC_arch PF05377.11 EKX50705.1 - 0.044 14.2 0.6 0.044 14.2 0.6 7.2 10 0 0 10 10 10 0 Flagella accessory protein C (FlaC) Rx_N PF18052.1 EKX50705.1 - 0.057 13.7 0.7 0.057 13.7 0.7 4.9 6 0 0 6 6 6 0 Rx N-terminal domain Mito_carr PF00153.27 EKX50706.1 - 3.5e-60 199.9 0.6 1.3e-18 66.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Dpy-30 PF05186.13 EKX50708.1 - 0.14 11.9 0.1 6.7 6.5 0.0 2.9 3 0 0 3 3 3 0 Dpy-30 motif Tetraspanin PF00335.20 EKX50710.1 - 0.3 10.8 0.5 0.38 10.4 0.5 1.1 1 0 0 1 1 1 0 Tetraspanin family PIH1_CS PF18201.1 EKX50711.1 - 2.3e-09 37.5 0.0 3.3e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 PIH1 CS-like domain OTU PF02338.19 EKX50713.1 - 9.7e-08 32.6 0.0 2.9e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease TRM13 PF05206.14 EKX50715.1 - 4.1e-67 226.5 0.0 7.5e-67 225.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-U11-48K PF05253.12 EKX50715.1 - 5.5e-06 26.2 2.9 1.2e-05 25.1 2.9 1.6 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger DUF5450 PF17529.2 EKX50715.1 - 0.066 13.3 0.9 0.14 12.2 0.9 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5450) GPR15L PF15854.5 EKX50715.1 - 2.6 8.3 10.0 0.063 13.5 1.7 2.5 3 0 0 3 3 3 0 G-protein coupled receptor ligand 15 DUF179 PF02622.15 EKX50716.1 - 1.6e-27 96.4 0.1 2.4e-14 53.6 0.0 2.6 2 1 0 2 2 2 2 Uncharacterized ACR, COG1678 Rib_5-P_isom_A PF06026.14 EKX50717.1 - 5.2e-62 208.5 0.0 6.1e-62 208.3 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 EKX50717.1 - 0.0012 18.8 0.0 0.82 9.6 0.0 2.5 3 0 0 3 3 3 2 DeoR C terminal sensor domain Sugar-bind PF04198.13 EKX50717.1 - 0.092 11.9 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain Cupin_4 PF08007.12 EKX50718.1 - 4.8e-20 72.3 0.1 9.8e-20 71.2 0.1 1.5 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 EKX50718.1 - 3.1e-07 30.4 0.1 0.00012 21.8 0.1 2.3 1 1 0 1 1 1 1 Cupin-like domain AraC_binding PF02311.19 EKX50718.1 - 0.045 13.7 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain DUF3491 PF11996.8 EKX50718.1 - 0.085 10.7 0.1 0.12 10.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3491) DUF573 PF04504.14 EKX50720.1 - 0.058 14.1 0.1 0.077 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF573 TMEM208_SND2 PF05620.11 EKX50722.1 - 1.6e-21 76.8 3.6 3.1e-21 75.9 3.6 1.4 1 1 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 PhoLip_ATPase_C PF16212.5 EKX50722.1 - 0.004 16.9 2.0 0.0053 16.5 2.0 1.2 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal TerC PF03741.16 EKX50722.1 - 0.16 11.6 3.4 1.5 8.5 3.4 2.0 1 1 0 1 1 1 0 Integral membrane protein TerC family DUF4896 PF16237.5 EKX50722.1 - 0.16 11.8 0.2 0.16 11.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4896) NAD_binding_10 PF13460.6 EKX50723.1 - 2.5e-15 56.8 0.0 1.2e-08 35.0 0.0 2.2 2 0 0 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 EKX50723.1 - 4.7e-06 26.3 0.0 4.7e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 EKX50723.1 - 4.4e-05 23.1 0.0 0.00018 21.0 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EKX50723.1 - 8.3e-05 22.1 0.0 0.00013 21.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 EKX50723.1 - 0.0003 19.9 0.0 0.00042 19.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EKX50723.1 - 0.00066 19.2 0.0 0.00092 18.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 EKX50723.1 - 0.0017 18.3 0.0 0.0033 17.3 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EKX50723.1 - 0.0028 16.8 0.0 0.0041 16.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EKX50723.1 - 0.025 13.7 0.0 6.3 5.8 0.0 2.5 3 0 0 3 3 3 0 RmlD substrate binding domain DapB_N PF01113.20 EKX50723.1 - 0.054 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF4200 PF13863.6 EKX50724.1 - 0.0077 16.6 8.9 0.0077 16.6 8.9 4.6 2 1 2 5 5 5 2 Domain of unknown function (DUF4200) Lebercilin PF15619.6 EKX50724.1 - 0.01 15.5 14.8 0.01 15.5 14.8 3.1 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF760 PF05542.11 EKX50724.1 - 0.052 13.9 0.9 0.22 11.9 0.9 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF760) Rx_N PF18052.1 EKX50724.1 - 0.096 13.0 0.6 0.096 13.0 0.6 4.5 1 1 3 4 4 4 0 Rx N-terminal domain Phage_int_SAM_2 PF12834.7 EKX50724.1 - 0.14 12.8 4.9 2.1 9.1 0.3 3.5 2 1 1 3 3 3 0 Phage integrase, N-terminal DUF3141 PF11339.8 EKX50724.1 - 0.21 10.0 3.5 0.31 9.4 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) DUF2894 PF11445.8 EKX50724.1 - 0.32 11.5 15.0 0.48 10.9 7.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2894) DUF4806 PF16064.5 EKX50724.1 - 1 9.7 6.4 1.3 9.3 0.3 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4806) ATG16 PF08614.11 EKX50724.1 - 2.4 8.3 41.7 1 9.5 9.4 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Beta_helix PF13229.6 EKX50725.1 - 0.085 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Right handed beta helix region SlyX PF04102.12 EKX50729.1 - 0.026 15.1 4.4 0.039 14.6 1.4 2.2 2 0 0 2 2 2 0 SlyX DUF2205 PF10224.9 EKX50729.1 - 0.2 11.7 5.3 0.52 10.3 1.7 2.2 2 0 0 2 2 2 0 Short coiled-coil protein APG6_N PF17675.1 EKX50729.1 - 0.89 10.1 11.6 3.3 8.2 0.5 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region DivIC PF04977.15 EKX50729.1 - 1.5 8.7 10.0 7.7 6.4 3.6 2.5 2 1 0 2 2 2 0 Septum formation initiator ZapB PF06005.12 EKX50729.1 - 2 8.9 10.8 9 6.8 0.2 2.5 2 1 0 2 2 2 0 Cell division protein ZapB DASH_Spc19 PF08287.11 EKX50729.1 - 4.9 7.0 13.6 2.2 8.1 5.0 2.1 1 1 1 2 2 2 0 Spc19 Pyr_redox_2 PF07992.14 EKX50730.1 - 4.1e-75 252.7 2.9 4.6e-75 252.6 1.3 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EKX50730.1 - 6.8e-38 129.3 0.9 6.8e-38 129.3 0.9 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EKX50730.1 - 2.4e-21 76.1 5.4 5.1e-20 71.8 0.1 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EKX50730.1 - 4.1e-20 72.2 2.1 3e-19 69.4 2.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EKX50730.1 - 2.2e-08 33.3 1.4 0.00096 18.0 0.0 3.2 2 1 1 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.7 EKX50730.1 - 3.9e-06 26.5 0.9 6.5e-05 22.5 0.1 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EKX50730.1 - 3e-05 23.5 0.4 0.00017 21.0 0.0 2.0 1 1 0 2 2 2 1 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 EKX50730.1 - 0.00042 19.6 0.0 0.0083 15.3 0.0 2.1 1 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EKX50730.1 - 0.0077 16.2 2.7 0.021 14.8 0.0 2.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 EKX50730.1 - 0.012 14.9 0.4 1.5 8.1 0.4 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 EKX50730.1 - 0.079 13.4 0.0 8.5 6.9 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 EKX50730.1 - 0.13 11.5 0.5 8.5 5.5 0.2 2.6 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.24 EKX50730.1 - 0.16 11.0 7.0 0.17 10.9 1.3 3.0 4 1 0 4 4 4 0 FAD binding domain DAO PF01266.24 EKX50730.1 - 0.46 10.0 12.7 3.6 7.1 0.0 3.7 4 0 0 4 4 3 0 FAD dependent oxidoreductase GIDA PF01134.22 EKX50730.1 - 0.53 9.3 12.7 0.016 14.3 4.3 2.5 3 1 0 3 3 3 0 Glucose inhibited division protein A Atx10homo_assoc PF09759.9 EKX50731.1 - 0.086 12.9 0.0 7.3 6.7 0.0 2.3 1 1 1 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Pkinase PF00069.25 EKX50732.1 - 1.1e-12 47.9 0.0 1.8e-12 47.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX50732.1 - 1.9e-10 40.5 0.0 2.2e-10 40.3 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX50732.1 - 0.0072 15.7 0.0 0.0097 15.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EKX50732.1 - 0.015 14.4 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Cys_rich_FGFR PF00839.17 EKX50732.1 - 0.043 14.0 0.3 0.095 12.9 0.3 1.5 1 0 0 1 1 1 0 Cysteine rich repeat Arm PF00514.23 EKX50734.1 - 0.00087 19.3 0.5 0.29 11.2 0.0 4.1 4 1 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EKX50734.1 - 0.053 13.9 0.7 0.25 11.7 0.1 2.4 2 1 0 2 2 2 0 HEAT repeats JmjC PF02373.22 EKX50736.1 - 3e-32 111.4 0.2 1.1e-31 109.6 0.2 2.1 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 EKX50736.1 - 4.4e-14 52.1 0.6 4.4e-14 52.1 0.6 1.9 2 0 0 2 2 2 1 jmjN domain DUF3416 PF11896.8 EKX50736.1 - 0.13 12.6 1.3 0.21 11.9 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3416) Lipase_3 PF01764.25 EKX50737.1 - 6.5e-17 61.7 0.0 1.7e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.20 EKX50737.1 - 9.8e-05 22.1 0.0 0.00012 21.8 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 EKX50737.1 - 0.0089 15.3 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2048 PF09752.9 EKX50737.1 - 0.035 13.2 0.1 0.068 12.2 0.0 1.5 2 0 0 2 2 2 0 Abhydrolase domain containing 18 Abhydrolase_6 PF12697.7 EKX50737.1 - 0.092 13.3 0.1 0.3 11.7 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 EKX50737.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Arm PF00514.23 EKX50739.1 - 5e-07 29.5 5.5 0.21 11.7 0.0 6.6 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.8 EKX50739.1 - 0.008 16.3 0.0 0.56 10.3 0.1 3.1 3 0 0 3 3 3 1 V-ATPase subunit H Arm_2 PF04826.13 EKX50739.1 - 0.0087 15.5 0.6 0.024 14.1 0.3 1.9 2 0 0 2 2 2 1 Armadillo-like Proteasom_PSMB PF10508.9 EKX50739.1 - 0.015 13.8 1.4 0.024 13.2 0.7 1.6 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit TAF6_C PF07571.13 EKX50739.1 - 0.07 13.5 0.5 2.4 8.6 0.0 3.0 4 0 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain HEAT_2 PF13646.6 EKX50739.1 - 0.082 13.3 12.4 8 6.9 0.3 5.4 3 2 2 5 5 5 0 HEAT repeats RTP1_C1 PF10363.9 EKX50739.1 - 0.14 12.4 1.5 2.4 8.4 0.2 2.5 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 EKX50739.1 - 0.18 11.8 1.4 0.55 10.2 1.0 1.9 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Methyltransf_4 PF02390.17 EKX50740.1 - 8.4e-12 44.9 0.0 1.2e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 EKX50740.1 - 4.7e-05 23.2 0.0 7.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX50740.1 - 8.6e-05 23.2 0.0 0.00017 22.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX50740.1 - 0.12 13.2 0.0 0.23 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Anti-TRAP PF15777.5 EKX50741.1 - 0.043 13.8 2.0 0.074 13.0 2.0 1.4 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein IMS PF00817.20 EKX50742.1 - 5.8e-51 172.4 0.0 7.8e-51 172.0 0.0 1.2 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.8 EKX50742.1 - 0.04 14.3 0.0 0.095 13.1 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif TFIIA PF03153.13 EKX50743.1 - 7.7e-37 128.3 11.1 9e-26 91.8 10.1 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 EKX50743.1 - 0.0095 15.7 10.9 0.014 15.2 10.9 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein TRAP_alpha PF03896.16 EKX50743.1 - 0.32 10.2 4.3 0.31 10.2 3.6 1.3 1 1 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 EKX50743.1 - 0.77 7.8 14.2 1.1 7.3 14.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 EKX50743.1 - 1.1 8.6 12.1 1.4 8.2 12.1 1.1 1 0 0 1 1 1 0 SDA1 RNA_pol_3_Rpc31 PF11705.8 EKX50743.1 - 1.8 8.8 15.0 2.6 8.3 15.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.10 EKX50743.1 - 3.5 8.1 16.5 0.55 10.7 12.4 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nop14 PF04147.12 EKX50743.1 - 5 5.2 16.0 6.1 4.9 16.0 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 EKX50743.1 - 6.3 6.0 13.9 8.3 5.6 13.9 1.1 1 0 0 1 1 1 0 BUD22 ABC_tran PF00005.27 EKX50744.1 - 1.2e-45 155.4 0.0 1.3e-22 80.8 0.0 2.7 2 1 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EKX50744.1 - 1.3e-23 82.8 4.0 3e-23 81.6 4.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EKX50744.1 - 5.6e-20 72.3 0.5 0.00031 20.7 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EKX50744.1 - 1.5e-08 35.4 0.5 0.015 15.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 EKX50744.1 - 3.1e-08 33.2 0.0 0.0047 16.6 0.0 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.19 EKX50744.1 - 5.5e-08 32.5 0.1 0.065 12.7 0.0 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EKX50744.1 - 4.5e-06 26.6 2.7 0.12 12.0 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 EKX50744.1 - 1.7e-05 25.1 0.0 0.022 15.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EKX50744.1 - 1.7e-05 25.1 0.0 0.043 14.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EKX50744.1 - 2e-05 24.5 0.1 0.029 14.3 0.0 2.8 2 1 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EKX50744.1 - 2.3e-05 24.4 0.0 0.035 14.2 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.29 EKX50744.1 - 3.4e-05 24.3 0.0 0.32 11.4 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX50744.1 - 6.1e-05 23.5 0.0 0.29 11.5 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 EKX50744.1 - 6.6e-05 23.5 0.0 0.45 11.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EKX50744.1 - 0.00011 22.6 1.9 1 9.8 0.0 3.3 3 0 0 3 3 3 1 RNA helicase AAA_25 PF13481.6 EKX50744.1 - 0.00017 21.2 0.0 0.36 10.4 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_27 PF13514.6 EKX50744.1 - 0.00029 20.5 0.0 0.32 10.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EKX50744.1 - 0.00037 20.3 0.6 0.93 9.2 0.1 2.7 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 EKX50744.1 - 0.00056 19.9 0.0 1.3 9.0 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.6 EKX50744.1 - 0.00088 19.4 0.0 0.32 11.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EKX50744.1 - 0.0014 18.7 0.2 0.71 9.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EKX50744.1 - 0.002 17.9 0.2 0.54 10.0 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EKX50744.1 - 0.0025 17.9 0.1 2.6 8.1 0.0 3.1 3 1 1 4 4 2 1 AAA domain Roc PF08477.13 EKX50744.1 - 0.0036 17.5 0.0 3.7 7.8 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EKX50744.1 - 0.0048 17.0 0.8 2.8 7.9 0.0 3.6 2 1 1 3 3 3 1 Dynamin family SRP54 PF00448.22 EKX50744.1 - 0.0055 16.4 0.2 2.9 7.5 0.1 2.8 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain TsaE PF02367.17 EKX50744.1 - 0.0099 15.9 0.0 4.2 7.4 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pox_A32 PF04665.12 EKX50744.1 - 0.023 14.1 0.0 0.98 8.8 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein PduV-EutP PF10662.9 EKX50744.1 - 0.023 14.4 1.5 15 5.3 0.3 3.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF2813 PF11398.8 EKX50744.1 - 0.024 13.9 0.0 0.34 10.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) AAA_7 PF12775.7 EKX50744.1 - 0.025 14.1 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 EKX50744.1 - 0.05 13.7 6.2 2 8.4 0.1 3.6 3 2 1 4 4 4 0 Helicase HerA, central domain MukB PF04310.12 EKX50744.1 - 0.078 12.8 0.5 10 5.9 0.0 2.8 3 0 0 3 3 3 0 MukB N-terminal NTPase_1 PF03266.15 EKX50744.1 - 0.13 12.1 0.1 3.5 7.5 0.1 2.6 2 0 0 2 2 2 0 NTPase DUF3584 PF12128.8 EKX50744.1 - 0.13 9.7 2.5 1.9 5.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) cobW PF02492.19 EKX50744.1 - 0.16 11.5 0.0 2 7.9 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DDE_Tnp_1_7 PF13843.6 EKX50745.1 - 3.3e-12 46.4 0.0 5.8e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Transposase IS4 WD40 PF00400.32 EKX50746.1 - 1.9e-50 167.7 34.2 0.00014 22.5 0.0 19.3 20 0 0 20 20 19 12 WD domain, G-beta repeat DUF667 PF05018.13 EKX50746.1 - 3.9e-30 105.0 0.2 7.2e-30 104.1 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF667) ANAPC4_WD40 PF12894.7 EKX50746.1 - 1.6e-23 82.8 0.0 0.0012 19.1 0.0 10.5 7 1 3 11 11 11 6 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EKX50746.1 - 2.8e-05 24.1 0.0 0.8 9.8 0.0 3.7 4 0 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Cytochrom_D1 PF02239.16 EKX50746.1 - 9.9e-05 21.0 0.1 0.23 10.0 0.0 3.2 1 1 2 3 3 3 2 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 EKX50746.1 - 0.00092 18.3 0.1 3 6.7 0.0 4.5 7 0 0 7 7 7 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 EKX50746.1 - 0.0021 17.2 0.1 2.3 7.1 0.0 3.6 3 1 1 4 4 4 2 Coatomer WD associated region HELP PF03451.14 EKX50746.1 - 0.017 15.0 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 HELP motif RAB3GAP2_N PF14655.6 EKX50746.1 - 0.037 13.3 0.0 0.26 10.5 0.0 2.4 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus IKI3 PF04762.12 EKX50746.1 - 0.054 11.5 0.1 5.9 4.7 0.1 3.1 3 0 0 3 3 3 0 IKI3 family PQQ_3 PF13570.6 EKX50746.1 - 0.087 13.3 3.1 30 5.3 0.2 5.1 5 0 0 5 5 4 0 PQQ-like domain Pterin_4a PF01329.19 EKX50747.1 - 5.9e-31 106.5 0.6 6.7e-31 106.3 0.6 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase HALZ PF02183.18 EKX50750.1 - 0.0076 16.5 12.8 0.36 11.1 6.7 2.8 2 0 0 2 2 2 2 Homeobox associated leucine zipper TMF_TATA_bd PF12325.8 EKX50750.1 - 0.018 15.3 7.0 0.018 15.3 7.0 3.8 5 0 0 5 5 5 0 TATA element modulatory factor 1 TATA binding ZapB PF06005.12 EKX50750.1 - 0.022 15.2 12.0 0.022 15.2 12.0 3.6 4 1 0 4 4 4 0 Cell division protein ZapB UPF0242 PF06785.11 EKX50750.1 - 2.9 7.9 28.5 0.019 15.0 9.2 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF3881 PF12997.7 EKX50750.1 - 4.6 6.4 7.0 10 5.3 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3881) LRR_6 PF13516.6 EKX50752.1 - 4e-05 23.3 14.0 0.29 11.3 0.2 6.2 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.7 EKX50752.1 - 0.0036 17.7 9.6 0.32 11.5 0.3 4.8 3 2 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX50752.1 - 0.18 11.6 14.2 9.2 6.1 0.0 5.3 5 1 0 5 5 5 0 Leucine rich repeat LRR_1 PF00560.33 EKX50752.1 - 0.18 12.4 5.5 1.5e+02 3.6 0.0 5.5 6 0 0 6 6 6 0 Leucine Rich Repeat ASC PF00858.24 EKX50753.1 - 0.46 9.4 1.7 0.66 8.9 0.9 1.4 1 1 0 1 1 1 0 Amiloride-sensitive sodium channel Methyltransf_16 PF10294.9 EKX50754.1 - 1.5e-16 60.6 0.1 1.3e-15 57.6 0.0 2.2 2 0 0 2 2 2 1 Lysine methyltransferase Leu_zip PF15294.6 EKX50754.1 - 0.0005 19.7 21.0 0.016 14.7 8.5 2.2 1 1 1 2 2 2 2 Leucine zipper Methyltransf_23 PF13489.6 EKX50754.1 - 0.003 17.4 0.0 0.0069 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ATG16 PF08614.11 EKX50754.1 - 0.018 15.3 30.8 0.068 13.4 23.8 2.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Methyltransf_12 PF08242.12 EKX50754.1 - 0.025 15.3 0.3 0.22 12.3 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain Macoilin PF09726.9 EKX50754.1 - 0.037 12.6 11.6 0.053 12.1 11.6 1.2 1 0 0 1 1 1 0 Macoilin family zf-C4H2 PF10146.9 EKX50754.1 - 0.045 14.1 7.5 0.11 12.8 7.5 1.7 1 0 0 1 1 1 0 Zinc finger-containing protein Atg14 PF10186.9 EKX50754.1 - 0.11 11.6 13.2 0.3 10.1 13.2 1.7 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Golgin_A5 PF09787.9 EKX50754.1 - 0.3 10.5 17.9 0.59 9.5 17.9 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4201 PF13870.6 EKX50754.1 - 0.3 10.8 16.6 1.2 8.8 16.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Pox_A_type_inc PF04508.12 EKX50754.1 - 0.77 9.7 4.7 1.3 9.0 1.2 3.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat AAA_13 PF13166.6 EKX50754.1 - 1.1 7.8 14.3 1.7 7.2 14.3 1.2 1 0 0 1 1 1 0 AAA domain COG5 PF10392.9 EKX50754.1 - 2 8.6 11.2 14 5.8 5.4 2.5 1 1 1 2 2 2 0 Golgi transport complex subunit 5 BRE1 PF08647.11 EKX50754.1 - 2.7 8.1 18.8 4.7 7.3 0.0 4.2 3 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase DUF724 PF05266.14 EKX50754.1 - 3.6 7.4 18.1 6.8 6.5 10.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Bacillus_HBL PF05791.11 EKX50754.1 - 3.8 7.3 8.1 0.62 9.9 1.6 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Fez1 PF06818.15 EKX50754.1 - 6.2 7.2 28.1 1.9e+02 2.4 22.7 3.6 2 1 1 3 3 3 0 Fez1 ING PF12998.7 EKX50754.1 - 7.6 7.2 11.0 44 4.7 0.2 2.7 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF4407 PF14362.6 EKX50754.1 - 7.9 5.7 15.8 5.2 6.3 13.5 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) zf-C3HC4_3 PF13920.6 EKX50755.1 - 3.9e-10 39.4 14.1 4.8e-10 39.1 14.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX50755.1 - 3.3e-05 23.7 13.5 5.3e-05 23.0 13.5 1.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EKX50755.1 - 0.00068 19.9 11.8 0.00068 19.9 11.8 1.6 1 1 0 1 1 1 1 Ring finger domain zf-met PF12874.7 EKX50755.1 - 0.34 11.4 0.1 0.34 11.4 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF2318 PF10080.9 EKX50755.1 - 2.5 8.3 8.9 3.4 7.8 8.9 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2318) RWP-RK PF02042.15 EKX50756.1 - 1.1e-16 60.5 0.0 3.2e-16 59.0 0.0 1.7 2 0 0 2 2 2 1 RWP-RK domain Trypan_PARP PF05887.11 EKX50756.1 - 0.0018 18.3 1.5 0.0024 17.9 1.5 1.1 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) HTH_8 PF02954.19 EKX50756.1 - 0.047 13.5 0.4 0.28 11.0 0.1 2.2 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family HEPN_DZIP3 PF18738.1 EKX50757.1 - 0.087 12.6 0.2 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 DZIP3/ hRUL138-like HEPN Pep3_Vps18 PF05131.14 EKX50758.1 - 9e-35 119.7 0.1 3.4e-34 117.8 0.0 2.0 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 EKX50758.1 - 8.1e-08 32.2 7.7 7.1e-05 22.7 0.1 3.4 2 1 0 3 3 3 2 Region in Clathrin and VPS Zn_ribbon_17 PF17120.5 EKX50758.1 - 1.2e-05 24.9 2.2 2.4e-05 23.9 2.2 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Vps39_2 PF10367.9 EKX50758.1 - 0.00049 20.5 0.1 0.0014 19.0 0.1 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 TPR_1 PF00515.28 EKX50758.1 - 0.00049 19.8 0.8 0.2 11.5 0.8 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Sema PF01403.19 EKX50758.1 - 0.0037 16.1 0.0 0.27 10.0 0.0 2.7 3 0 0 3 3 3 1 Sema domain zf-ANAPC11 PF12861.7 EKX50758.1 - 0.0052 16.8 0.3 0.017 15.2 0.3 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_7 PF13176.6 EKX50758.1 - 0.021 14.8 4.1 23 5.3 0.3 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-rbx1 PF12678.7 EKX50758.1 - 0.023 15.0 2.3 0.023 15.0 2.3 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EKX50758.1 - 0.07 13.5 8.8 0.034 14.5 5.1 2.4 2 0 0 2 2 2 0 Ring finger domain DUF2430 PF10353.9 EKX50758.1 - 0.1 13.0 0.1 0.22 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2430) RPN1_RPN2_N PF17781.1 EKX50758.1 - 0.15 11.4 4.6 1.2 8.5 0.1 2.8 2 1 1 3 3 3 0 RPN1/RPN2 N-terminal domain TPR_2 PF07719.17 EKX50758.1 - 0.49 10.6 4.9 10 6.5 0.4 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-RING_11 PF17123.5 EKX50758.1 - 1.1 9.1 8.9 3.6 7.4 8.9 1.9 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 EKX50758.1 - 9.6 6.2 11.0 0.58 10.0 4.9 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ank_4 PF13637.6 EKX50759.1 - 1.2e-17 64.1 0.1 1.2e-09 38.5 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX50759.1 - 7.7e-13 48.4 0.9 8.8e-08 32.3 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX50759.1 - 1.1e-11 43.8 0.2 3.4e-05 23.9 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EKX50759.1 - 1.3e-11 44.4 0.6 1.1e-05 25.6 0.2 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EKX50759.1 - 1.9e-11 44.4 0.0 2.2e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Cupin_3 PF05899.12 EKX50760.1 - 0.0098 15.6 0.2 0.016 14.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Mitochondr_Som1 PF11093.8 EKX50760.1 - 0.13 12.2 0.5 0.23 11.5 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial export protein Som1 EF-hand_1 PF00036.32 EKX50762.1 - 1.2e-14 52.7 12.2 6.3e-08 31.6 0.2 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 EKX50762.1 - 4.9e-14 52.5 8.2 1.7e-06 28.3 1.2 2.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EKX50762.1 - 1.5e-13 49.5 12.0 3.2e-07 29.7 0.6 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EKX50762.1 - 1.6e-11 43.2 5.9 2.7e-06 26.6 0.0 3.2 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 EKX50762.1 - 4e-10 39.4 9.6 0.0012 18.6 0.1 3.8 3 1 1 4 4 4 3 EF-hand domain pair NmrA PF05368.13 EKX50763.1 - 2e-09 37.3 0.1 3.2e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EKX50763.1 - 1.1e-06 28.7 2.0 4.4e-06 26.7 2.1 1.8 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EKX50763.1 - 0.0033 16.5 0.2 0.0051 15.9 0.2 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family SoxZ PF08770.11 EKX50764.1 - 0.029 14.1 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Sulphur oxidation protein SoxZ Pkinase PF00069.25 EKX50765.1 - 2.6e-50 171.2 0.0 3e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX50765.1 - 8.9e-33 113.7 0.0 1e-32 113.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX50765.1 - 0.0003 20.2 0.0 0.0012 18.2 0.0 1.8 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EKX50765.1 - 0.0048 15.7 0.0 0.0054 15.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX50765.1 - 0.0068 16.4 0.2 0.18 11.7 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EKX50765.1 - 0.019 13.9 0.0 0.034 13.1 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 EKX50765.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DUF179 PF02622.15 EKX50766.1 - 9.7e-22 77.6 0.0 1.5e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 Bac_rhodopsin PF01036.18 EKX50768.1 - 3.4e-22 79.1 17.2 5.1e-22 78.6 17.2 1.2 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF2070 PF09843.9 EKX50768.1 - 0.22 9.8 10.3 0.3 9.3 10.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF1664 PF07889.12 EKX50769.1 - 9.4 6.3 23.9 1 9.4 0.4 4.6 2 2 2 5 5 5 0 Protein of unknown function (DUF1664) Ephrin_rec_like PF07699.13 EKX50771.1 - 1.9e-09 37.1 63.2 9.1e-06 25.3 8.2 5.4 4 2 1 5 5 5 4 Putative ephrin-receptor like Stanniocalcin PF03298.13 EKX50771.1 - 0.017 14.5 3.2 0.026 13.9 3.2 1.3 1 0 0 1 1 1 0 Stanniocalcin family TNFR_c6 PF00020.18 EKX50771.1 - 0.17 12.3 51.4 0.17 12.3 2.2 6.2 4 2 1 5 5 5 0 TNFR/NGFR cysteine-rich region EGF_2 PF07974.13 EKX50771.1 - 0.26 11.7 0.2 0.26 11.7 0.2 6.9 5 2 2 7 7 7 0 EGF-like domain EGF_MSP1_1 PF12946.7 EKX50771.1 - 1.3 9.2 22.9 0.18 11.9 0.6 5.0 4 1 1 5 5 5 0 MSP1 EGF domain 1 EamA PF00892.20 EKX50772.1 - 8e-07 29.3 24.2 1.5e-05 25.2 9.0 2.9 1 1 2 3 3 3 2 EamA-like transporter family TPT PF03151.16 EKX50772.1 - 2.8e-05 23.6 19.5 3.3e-05 23.4 19.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Glycos_transf_2 PF00535.26 EKX50773.1 - 0.011 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 PDZ_6 PF17820.1 EKX50774.1 - 2.3e-06 27.3 0.1 3.9e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX50774.1 - 6.8e-05 23.1 0.1 0.00013 22.3 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX50774.1 - 7.1e-05 23.0 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Peptidase_M1_N PF17900.1 EKX50774.1 - 0.21 11.8 0.2 0.45 10.7 0.1 1.5 2 0 0 2 2 2 0 Peptidase M1 N-terminal domain Ank_2 PF12796.7 EKX50775.1 - 2.6e-19 69.6 2.1 2.7e-07 31.1 0.0 9.1 7 2 2 9 9 9 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX50775.1 - 1.1e-15 56.2 10.4 0.01 16.3 0.1 11.0 11 0 0 11 11 11 4 Ankyrin repeat Ank PF00023.30 EKX50775.1 - 1.9e-11 43.9 2.5 0.035 14.6 0.2 7.5 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 EKX50775.1 - 4e-11 42.9 2.2 0.017 15.4 0.0 6.5 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX50775.1 - 6.6e-11 42.5 10.0 7.4e-06 26.4 0.0 8.2 9 0 0 9 9 9 2 Ankyrin repeats (many copies) AAA_16 PF13191.6 EKX50775.1 - 0.0017 18.8 0.1 0.022 15.2 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain Mago_nashi PF02792.14 EKX50776.1 - 1.1e-73 246.0 0.3 1.2e-73 245.9 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein HORMA PF02301.18 EKX50777.1 - 2.3e-27 96.0 1.1 3.3e-27 95.5 1.1 1.2 1 0 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 EKX50777.1 - 0.01 15.7 0.2 0.024 14.5 0.1 1.7 2 0 0 2 2 2 0 Bacterial HORMA domain 2 DUF3914 PF13053.6 EKX50777.1 - 0.096 13.0 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3914) Aldo_ket_red PF00248.21 EKX50778.1 - 3.8e-34 118.2 0.0 1.8e-16 60.2 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family Ank_2 PF12796.7 EKX50779.1 - 3.2e-28 98.1 0.4 3.8e-16 59.5 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX50779.1 - 6.9e-27 93.5 0.3 5.5e-11 42.8 0.0 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX50779.1 - 1.4e-24 83.4 0.0 0.00022 21.4 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 EKX50779.1 - 1.8e-24 85.0 3.8 1.1e-05 25.7 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 EKX50779.1 - 1.7e-20 72.8 0.9 1.2e-10 41.5 0.1 4.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) PEGA PF08308.11 EKX50779.1 - 0.016 15.1 0.0 0.7 9.8 0.0 2.4 2 0 0 2 2 2 0 PEGA domain BTB_2 PF02214.22 EKX50781.1 - 0.00094 19.5 0.7 3.6 8.0 0.0 3.9 3 0 0 3 3 3 3 BTB/POZ domain Lactamase_B_2 PF12706.7 EKX50782.1 - 3.8e-17 62.5 0.0 9.6e-13 48.1 0.0 2.2 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EKX50782.1 - 0.056 13.4 0.4 0.095 12.7 0.4 1.5 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily TPR_14 PF13428.6 EKX50783.1 - 4.5e-12 45.7 2.0 0.0012 19.4 0.1 5.9 2 1 4 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX50783.1 - 5.2e-12 45.9 2.1 6.3e-08 32.8 0.1 5.0 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX50783.1 - 2.2e-11 44.1 5.4 2.5e-06 27.9 0.5 4.1 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX50783.1 - 3.1e-11 42.5 5.1 0.01 15.9 0.1 5.1 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX50783.1 - 8.5e-11 41.2 5.4 0.0011 18.6 0.1 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX50783.1 - 1e-07 32.5 0.6 0.025 15.2 0.1 4.0 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX50783.1 - 4.1e-05 23.2 8.1 0.13 12.0 1.9 4.5 5 0 0 5 5 4 2 TPR repeat TPR_7 PF13176.6 EKX50783.1 - 9.1e-05 22.2 8.4 0.028 14.4 0.0 5.0 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 EKX50783.1 - 0.00041 20.6 0.4 0.29 11.5 0.0 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_3 PF07720.12 EKX50783.1 - 0.00084 19.3 0.5 3.8 7.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 EKX50783.1 - 0.0045 16.2 1.4 0.6 9.3 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX50783.1 - 0.0046 17.1 10.2 0.041 14.1 0.2 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX50783.1 - 0.0048 16.3 0.1 0.033 13.6 0.1 2.2 2 0 0 2 2 2 1 MalT-like TPR region ANAPC3 PF12895.7 EKX50783.1 - 0.005 17.0 8.7 0.023 14.9 0.5 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EKX50783.1 - 0.0079 16.8 3.6 6 7.7 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat BTAD PF03704.17 EKX50783.1 - 0.014 15.9 4.5 0.67 10.4 0.1 3.3 2 1 1 3 3 3 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 EKX50783.1 - 0.02 14.7 10.4 2.4 8.1 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TAF1_subA PF14929.6 EKX50783.1 - 0.029 13.8 0.9 0.1 12.0 0.2 1.9 2 0 0 2 2 2 0 TAF RNA Polymerase I subunit A DUF1347 PF07079.11 EKX50783.1 - 0.032 12.8 0.8 0.17 10.4 0.1 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1347) Rapsyn_N PF10579.9 EKX50783.1 - 0.065 13.3 0.1 1 9.5 0.1 3.0 3 1 0 3 3 3 0 Rapsyn N-terminal myristoylation and linker region Complex1_51K PF01512.17 EKX50783.1 - 0.088 12.7 0.2 0.45 10.4 0.1 2.1 2 1 0 2 2 2 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit MIT PF04212.18 EKX50783.1 - 0.09 12.9 8.3 17 5.5 0.0 5.0 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain DUF5113 PF17140.4 EKX50783.1 - 0.11 12.3 0.1 0.38 10.5 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) KH_1 PF00013.29 EKX50784.1 - 1.4e-10 40.8 0.1 3e-10 39.8 0.1 1.6 1 0 0 1 1 1 1 KH domain zf-UDP PF14569.6 EKX50784.1 - 0.0042 17.2 0.0 1.1e+02 3.0 0.0 4.5 2 1 3 5 5 5 0 Zinc-binding RING-finger KH_2 PF07650.17 EKX50784.1 - 0.02 14.7 0.7 0.067 13.0 0.7 1.9 1 0 0 1 1 1 0 KH domain Activator_LAG-3 PF11498.8 EKX50784.1 - 0.031 13.3 3.6 0.057 12.4 3.6 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CooC_C PF15976.5 EKX50784.1 - 0.2 11.7 1.3 6.8 6.8 0.1 2.9 3 0 0 3 3 3 0 CS1-pili formation C-terminal Qua1 PF16274.5 EKX50785.1 - 0.00074 19.3 1.4 0.048 13.5 0.4 2.6 2 0 0 2 2 2 2 Qua1 domain DUF1799 PF08809.11 EKX50785.1 - 0.11 12.7 0.0 19 5.5 0.0 2.5 2 0 0 2 2 2 0 Phage related hypothetical protein (DUF1799) Syntaxin-6_N PF09177.11 EKX50785.1 - 4.9 7.8 10.6 1.1 9.9 0.7 3.4 3 1 1 4 4 4 0 Syntaxin 6, N-terminal ADH_zinc_N_2 PF13602.6 EKX50786.1 - 2e-16 61.3 0.0 7.8e-16 59.3 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EKX50786.1 - 1e-10 41.7 0.0 2.4e-10 40.5 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EKX50786.1 - 1.9e-09 37.4 0.5 1.2e-08 34.8 0.5 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PBP1_TM PF14812.6 EKX50786.1 - 0.044 14.1 0.2 0.079 13.3 0.2 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BetR PF08667.10 EKX50786.1 - 0.082 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 BetR domain NUP50 PF08911.11 EKX50786.1 - 0.12 13.0 0.3 0.67 10.6 0.2 2.1 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) ABC1 PF03109.16 EKX50787.1 - 4.5e-29 101.0 0.0 8.3e-29 100.2 0.0 1.5 1 0 0 1 1 1 1 ABC1 family WaaY PF06176.11 EKX50787.1 - 0.0047 16.6 0.0 0.0084 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase PF00069.25 EKX50787.1 - 0.024 14.0 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain APH PF01636.23 EKX50787.1 - 0.095 12.6 0.4 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-RING_2 PF13639.6 EKX50788.1 - 3.4e-05 24.1 10.1 3.4e-05 24.1 10.1 3.0 3 0 0 3 3 3 1 Ring finger domain PHD PF00628.29 EKX50788.1 - 0.00022 21.1 8.7 0.00022 21.1 8.7 3.0 2 2 0 2 2 2 1 PHD-finger zf-C3HC4_2 PF13923.6 EKX50788.1 - 0.0081 16.0 9.2 0.0081 16.0 9.2 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX50788.1 - 0.014 15.7 8.0 0.014 15.7 8.0 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EKX50788.1 - 0.02 14.7 8.9 0.02 14.7 8.9 2.7 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_14 PF17978.1 EKX50788.1 - 8.6 6.9 10.9 0.4 11.1 4.0 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain TPR_12 PF13424.6 EKX50789.1 - 1.9e-05 24.9 14.2 0.027 14.8 2.2 3.9 4 1 0 4 4 4 2 Tetratricopeptide repeat RPN7 PF10602.9 EKX50789.1 - 0.0074 16.0 0.7 0.12 12.1 0.1 2.7 2 1 1 3 3 3 1 26S proteasome subunit RPN7 TPR_2 PF07719.17 EKX50789.1 - 0.015 15.3 9.6 4.2 7.7 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX50789.1 - 0.042 14.7 15.5 26 6.0 0.9 5.6 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF1771 PF08590.10 EKX50789.1 - 0.099 13.0 0.7 0.63 10.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) SNAP PF14938.6 EKX50789.1 - 0.1 12.0 2.5 0.53 9.7 0.2 2.8 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_9 PF13371.6 EKX50789.1 - 0.13 12.5 10.1 0.15 12.2 0.7 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX50789.1 - 0.5 10.7 7.2 12 6.4 0.1 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat ANAPC5 PF12862.7 EKX50789.1 - 0.97 9.5 3.2 21 5.3 0.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 SAM_1 PF00536.30 EKX50790.1 - 8.4e-07 29.3 0.3 1.7e-06 28.3 0.3 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EKX50790.1 - 6.8e-05 22.9 0.4 0.00014 21.9 0.1 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 EKX50790.1 - 0.15 12.0 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Gcd10p PF04189.13 EKX50792.1 - 2.4e-53 181.2 0.0 3e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Gcd10p family DHHC PF01529.20 EKX50793.1 - 1.2e-26 93.4 14.3 1.2e-26 93.4 14.3 1.5 1 1 1 2 2 2 1 DHHC palmitoyltransferase NnrS PF05940.12 EKX50793.1 - 0.0035 16.8 0.6 0.0041 16.6 0.6 1.1 1 0 0 1 1 1 1 NnrS protein SOBP PF15279.6 EKX50794.1 - 0.024 15.3 17.7 0.031 14.9 17.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein CDC45 PF02724.14 EKX50794.1 - 3.1 6.0 7.8 3.6 5.8 7.8 1.0 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 EKX50794.1 - 3.9 7.2 11.5 4.9 6.9 11.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4407 PF14362.6 EKX50794.1 - 6 6.1 5.8 7.5 5.8 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SPOUT_MTase PF02590.17 EKX50795.1 - 2.4e-39 134.8 0.0 2.8e-39 134.6 0.0 1.0 1 0 0 1 1 1 1 Predicted SPOUT methyltransferase Methyltransf_11 PF08241.12 EKX50796.1 - 3.9e-10 40.2 0.1 6.7e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX50796.1 - 1.6e-07 32.0 0.1 2.8e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX50796.1 - 1.5e-06 28.1 0.0 2.2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EKX50796.1 - 7.2e-06 25.5 0.0 1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 EKX50796.1 - 0.0088 16.2 0.1 0.022 14.9 0.1 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.12 EKX50796.1 - 0.0089 16.7 0.0 0.015 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX50796.1 - 0.011 15.5 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_29 PF03141.16 EKX50796.1 - 0.052 12.1 0.0 6.4 5.2 0.0 2.1 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MIP-T3 PF10243.9 EKX50798.1 - 9.8e-36 122.2 0.0 2.7e-35 120.7 0.0 1.8 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CH-like domain MIP-T3_C PF17749.1 EKX50798.1 - 1.9e-29 102.6 16.2 1.9e-29 102.6 16.2 1.8 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region Spectrin PF00435.21 EKX50798.1 - 0.0087 16.5 12.3 0.26 11.8 6.4 2.5 2 0 0 2 2 2 2 Spectrin repeat RasGAP_C PF03836.15 EKX50798.1 - 0.065 13.4 7.9 0.14 12.3 7.3 1.8 1 1 0 1 1 1 0 RasGAP C-terminus CC2-LZ PF16516.5 EKX50798.1 - 0.42 11.0 15.3 0.21 11.9 5.1 2.5 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Nup88 PF10168.9 EKX50798.1 - 0.45 8.3 13.9 0.64 7.8 13.9 1.1 1 0 0 1 1 1 0 Nuclear pore component Z1 PF10593.9 EKX50798.1 - 0.95 8.9 5.5 1 8.8 4.2 1.5 1 1 0 1 1 1 0 Z1 domain Mis12 PF05859.12 EKX50798.1 - 1.3 9.1 11.2 0.34 11.0 0.3 2.7 1 1 1 2 2 2 0 Mis12 protein LMBR1 PF04791.16 EKX50798.1 - 8 5.2 6.2 11 4.7 6.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Glyco_hydro_20 PF00728.22 EKX50799.1 - 1.8e-16 60.5 0.1 9.1e-16 58.2 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 EKX50799.1 - 6.1e-12 46.4 0.0 2.8e-11 44.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 PF14845.6 EKX50799.1 - 0.00016 22.4 0.0 0.0017 19.0 0.0 2.3 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like DSPc PF00782.20 EKX50801.1 - 6e-14 52.0 0.0 7.6e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX50801.1 - 0.075 12.6 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase zf-TRAF PF02176.18 EKX50802.1 - 2.2e-10 41.1 31.8 8e-08 32.9 4.5 3.0 2 1 1 3 3 3 3 TRAF-type zinc finger zf-met PF12874.7 EKX50802.1 - 0.13 12.7 8.5 3.8 8.0 0.2 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-ACC PF17848.1 EKX50802.1 - 0.67 10.1 16.3 39 4.4 0.4 5.4 4 1 1 5 5 5 0 Acetyl-coA carboxylase zinc finger domain zf_UBZ PF18439.1 EKX50802.1 - 1.1 8.9 18.0 0.41 10.3 1.1 5.0 5 1 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-CCHC_2 PF13696.6 EKX50802.1 - 3.8 7.4 8.3 2.5 8.0 0.1 3.1 3 0 0 3 3 3 0 Zinc knuckle WD40 PF00400.32 EKX50803.1 - 5.7e-13 49.1 2.7 0.0083 17.0 0.0 4.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Hira PF07569.11 EKX50803.1 - 0.018 14.8 0.1 2.4 7.8 0.0 2.7 2 1 1 3 3 3 0 TUP1-like enhancer of split Rav1p_C PF12234.8 EKX50803.1 - 0.021 13.3 0.0 0.024 13.1 0.0 1.0 1 0 0 1 1 1 0 RAVE protein 1 C terminal ANAPC4_WD40 PF12894.7 EKX50803.1 - 0.035 14.4 0.0 0.073 13.4 0.0 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX50803.1 - 0.068 12.1 0.0 0.3 10.0 0.0 1.8 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1415 PF07209.12 EKX50804.1 - 1.3e-38 132.4 0.0 1.9e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1415) BK_channel_a PF03493.18 EKX50805.1 - 1.2e-28 99.1 0.1 6.2e-26 90.5 0.1 2.5 2 0 0 2 2 2 2 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 EKX50805.1 - 4.2e-13 49.1 9.7 7.9e-13 48.2 9.7 1.4 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX50805.1 - 5.4e-11 42.3 1.0 1.6e-10 40.8 1.0 1.7 1 0 0 1 1 1 1 Ion channel TrkA_N PF02254.18 EKX50805.1 - 0.012 15.8 0.1 9.4 6.5 0.1 2.6 2 1 0 2 2 2 0 TrkA-N domain Methyltransf_11 PF08241.12 EKX50807.1 - 3.3e-13 50.1 0.0 6.5e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX50807.1 - 1.6e-10 41.5 0.3 5.4e-10 39.9 0.1 2.0 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX50807.1 - 2.2e-05 24.3 0.0 3.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX50807.1 - 2.3e-05 25.0 0.1 0.00068 20.3 0.1 2.8 2 1 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 EKX50807.1 - 0.00012 21.7 0.0 0.00017 21.2 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 EKX50807.1 - 0.00024 21.1 0.0 0.00037 20.4 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_23 PF13489.6 EKX50807.1 - 0.00033 20.5 0.0 0.0005 19.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX50807.1 - 0.002 17.5 0.0 0.032 13.6 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 EKX50807.1 - 0.004 16.1 0.0 0.013 14.4 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 EKX50807.1 - 0.045 13.0 0.1 0.16 11.2 0.1 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase NodS PF05401.11 EKX50807.1 - 0.085 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) DnaB_bind PF10410.9 EKX50807.1 - 0.099 12.8 0.1 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase Pkinase PF00069.25 EKX50808.1 - 5.2e-29 101.4 0.0 5.3e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX50808.1 - 2.2e-23 82.9 0.0 2.4e-23 82.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX50808.1 - 0.0045 15.8 0.0 0.005 15.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX50808.1 - 0.011 15.6 0.0 0.02 14.9 0.0 1.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family RCC1 PF00415.18 EKX50809.1 - 4.8e-35 120.0 23.1 8.8e-12 45.5 0.4 6.2 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX50809.1 - 5.6e-20 70.6 35.9 2.8e-09 36.5 0.1 6.2 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat PP2C PF00481.21 EKX50810.1 - 1.8e-51 175.3 0.0 2.2e-46 158.6 0.0 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EKX50810.1 - 4.6e-06 26.4 0.2 2.5e-05 24.0 0.2 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C CCDC24 PF15669.5 EKX50810.1 - 0.014 15.3 0.5 0.025 14.4 0.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family SlyX PF04102.12 EKX50811.1 - 0.15 12.7 4.3 0.23 12.1 0.7 2.8 2 0 0 2 2 2 0 SlyX LRR_6 PF13516.6 EKX50812.1 - 3.7e-17 60.8 7.6 0.00045 20.1 0.0 7.3 7 0 0 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.33 EKX50812.1 - 3e-06 27.0 0.8 1.5 9.7 0.1 6.2 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_4 PF12799.7 EKX50812.1 - 0.061 13.8 1.6 10 6.7 0.0 4.2 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) Ank_2 PF12796.7 EKX50813.1 - 1.1e-13 51.6 0.0 1.3e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX50813.1 - 1.3e-13 50.9 0.0 1.7e-09 37.8 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX50813.1 - 2.2e-13 50.4 0.1 4.3e-07 30.3 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX50813.1 - 9.2e-12 44.8 0.0 8.9e-05 22.8 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EKX50813.1 - 3.5e-11 42.3 0.0 0.0031 17.9 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat HEAT_2 PF13646.6 EKX50814.1 - 3.5e-14 52.9 3.4 3.8e-07 30.4 0.1 4.2 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.22 EKX50814.1 - 4.2e-06 26.5 4.5 1.3 9.5 0.0 6.1 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.7 EKX50814.1 - 0.048 13.7 0.1 0.46 10.5 0.0 2.4 1 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EKX50814.1 - 0.1 11.2 0.0 7.1 5.1 0.0 2.2 1 1 2 3 3 3 0 Adaptin N terminal region HEAT_PBS PF03130.16 EKX50814.1 - 0.12 13.1 0.2 4 8.4 0.0 3.3 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat RNA_pol_Rpb2_2 PF04561.14 EKX50814.1 - 0.13 11.9 0.0 0.48 10.0 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 2 HEAT_EZ PF13513.6 EKX50814.1 - 0.39 11.3 1.7 41 4.8 0.0 4.0 3 1 2 5 5 5 0 HEAT-like repeat DUF3789 PF12664.7 EKX50815.1 - 0.0071 16.0 0.4 0.012 15.3 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3789) NPR3 PF03666.13 EKX50815.1 - 0.1 11.3 1.3 0.11 11.3 1.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RRN3 PF05327.11 EKX50815.1 - 0.62 8.5 24.7 0.6 8.6 24.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SAPS PF04499.15 EKX50815.1 - 1.3 7.8 6.8 1.2 7.8 6.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SpoIIIAH PF12685.7 EKX50815.1 - 2.4 7.9 7.5 2.4 7.9 7.5 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Nop14 PF04147.12 EKX50815.1 - 3.9 5.6 35.2 4.3 5.4 35.2 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EKX50815.1 - 3.9 6.8 32.0 4.1 6.7 32.0 1.1 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 EKX50815.1 - 4.4 6.5 51.4 1.4 8.2 48.8 1.5 1 1 0 2 2 2 0 NOA36 protein CobT PF06213.12 EKX50815.1 - 5.8 6.2 23.4 6.6 6.0 23.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT IQ PF00612.27 EKX50816.1 - 0.026 14.3 0.0 0.073 12.9 0.0 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif Dehydratase_SU PF02287.15 EKX50816.1 - 0.039 14.0 5.9 0.039 14.0 3.8 2.1 2 0 0 2 2 2 0 Dehydratase small subunit PhoLip_ATPase_C PF16212.5 EKX50817.1 - 8e-50 169.9 19.6 8e-50 169.9 19.6 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal E1-E2_ATPase PF00122.20 EKX50817.1 - 1e-15 57.8 0.0 1e-15 57.8 0.0 3.2 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EKX50817.1 - 3.8e-15 56.7 1.8 1.7e-07 31.7 0.5 3.2 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase PhoLip_ATPase_N PF16209.5 EKX50817.1 - 9.7e-15 54.0 3.1 2.5e-14 52.7 3.1 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EKX50817.1 - 5.2e-11 42.5 0.0 5.9e-09 35.9 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EKX50817.1 - 0.00094 19.0 0.1 0.0023 17.7 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UPF0093 PF03653.13 EKX50817.1 - 7.2 6.8 11.6 3.6 7.8 1.3 3.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0093) rhaM PF05336.13 EKX50818.1 - 1.4e-12 47.6 0.0 2e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 L-rhamnose mutarotase COX14 PF14880.6 EKX50818.1 - 0.051 13.4 0.1 0.096 12.5 0.1 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Beta_helix PF13229.6 EKX50819.1 - 0.004 17.0 0.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 2 Right handed beta helix region SoxG PF04268.12 EKX50819.1 - 0.084 13.0 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Sarcosine oxidase, gamma subunit family TCR_zetazeta PF11628.8 EKX50821.1 - 0.011 15.3 0.2 0.027 14.2 0.2 1.6 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 zeta chain Ribosomal_L16 PF00252.18 EKX50822.1 - 2.1e-35 121.6 0.5 2.7e-35 121.2 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e SRP9-21 PF05486.12 EKX50823.1 - 1.4e-11 44.6 5.7 3.8e-11 43.2 0.7 2.8 2 1 0 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) KAP PF05804.12 EKX50823.1 - 0.0081 14.4 1.8 0.0088 14.3 1.8 1.0 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) LRR_8 PF13855.6 EKX50824.1 - 8e-36 121.6 35.6 7.4e-09 35.3 0.8 8.4 7 0 0 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 EKX50824.1 - 2.5e-26 91.3 41.1 0.00066 20.0 3.9 9.5 7 3 2 9 9 9 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX50824.1 - 7.8e-10 38.5 14.7 0.076 12.5 0.1 6.7 6 0 0 6 6 6 5 Leucine-rich repeat LRR_6 PF13516.6 EKX50824.1 - 1.6e-09 37.0 38.0 0.032 14.3 0.2 13.0 13 0 0 13 13 13 4 Leucine Rich repeat LRR_1 PF00560.33 EKX50824.1 - 0.045 14.3 39.5 17 6.5 0.4 13.5 14 1 0 14 14 14 0 Leucine Rich Repeat Pkinase PF00069.25 EKX50825.1 - 2.7e-45 154.8 0.0 3.2e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX50825.1 - 2.6e-29 102.3 0.0 3.1e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX50825.1 - 2.5e-06 27.0 0.0 3.6e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX50825.1 - 0.00019 21.5 0.1 0.0025 17.8 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EKX50825.1 - 0.001 18.7 0.2 0.01 15.5 0.0 1.9 2 0 0 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 EKX50825.1 - 0.0097 14.9 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Mo25 PF08569.11 EKX50826.1 - 0.0022 17.4 0.3 0.032 13.6 0.0 3.0 3 1 0 3 3 3 1 Mo25-like Arm PF00514.23 EKX50826.1 - 0.0027 17.7 30.9 0.71 10.0 0.1 11.2 12 0 0 12 12 12 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EKX50826.1 - 0.0063 17.0 24.0 0.013 16.0 0.8 6.9 7 0 0 7 7 7 2 HEAT-like repeat HEAT_2 PF13646.6 EKX50826.1 - 8.5 6.9 29.1 0.63 10.5 1.2 8.6 9 2 1 10 10 10 0 HEAT repeats Patatin PF01734.22 EKX50827.1 - 1.6e-07 31.7 0.2 2.1e-07 31.3 0.2 1.2 1 0 0 1 1 1 1 Patatin-like phospholipase Methyltransf_5 PF01795.19 EKX50828.1 - 4.3e-89 299.1 0.0 2.7e-88 296.4 0.0 1.9 1 1 0 1 1 1 1 MraW methylase family Methyltransf_31 PF13847.6 EKX50828.1 - 0.0014 18.4 0.0 0.077 12.8 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX50828.1 - 0.0016 19.1 0.0 0.0079 16.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX50828.1 - 0.11 13.1 0.0 1.8 9.2 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Kinesin PF00225.23 EKX50829.1 - 1.4e-104 349.6 0.0 1.8e-104 349.3 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX50829.1 - 5.6e-45 152.9 0.0 9.3e-45 152.2 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding YabA PF06156.13 EKX50829.1 - 0.15 12.7 6.2 2.5 8.8 0.7 4.2 4 1 0 4 4 4 0 Initiation control protein YabA AAA_22 PF13401.6 EKX50829.1 - 0.15 12.4 0.4 0.36 11.1 0.4 1.8 1 1 0 1 1 1 0 AAA domain DUF2358 PF10184.9 EKX50830.1 - 2e-07 31.2 0.0 2.7e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 EKX50830.1 - 0.0012 19.4 0.0 0.002 18.8 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain Dynamin_N PF00350.23 EKX50831.1 - 2.9e-14 53.5 0.0 1.1e-13 51.6 0.0 1.8 1 1 0 1 1 1 1 Dynamin family EHD_N PF16880.5 EKX50831.1 - 6.4e-14 51.5 0.9 9.8e-14 51.0 0.9 1.3 1 0 0 1 1 1 1 N-terminal EH-domain containing protein MMR_HSR1 PF01926.23 EKX50831.1 - 2.4e-09 37.3 0.0 6.1e-09 36.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF5600 PF18150.1 EKX50831.1 - 0.0007 20.2 3.1 0.0012 19.4 1.5 2.2 3 0 0 3 3 2 1 Domain of unknown function (DUF5600) Roc PF08477.13 EKX50831.1 - 0.00095 19.4 0.2 0.18 12.1 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 EKX50831.1 - 0.001 18.7 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA_16 PF13191.6 EKX50831.1 - 0.005 17.2 0.1 0.016 15.6 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EKX50831.1 - 0.0056 16.6 0.3 1.8 8.5 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase Gtr1_RagA PF04670.12 EKX50831.1 - 0.014 14.7 0.1 0.41 10.0 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_28 PF13521.6 EKX50831.1 - 0.026 14.8 0.1 0.16 12.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain SRPRB PF09439.10 EKX50831.1 - 0.028 13.9 0.0 2 7.8 0.0 2.5 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Ras PF00071.22 EKX50831.1 - 0.05 13.2 0.3 6.3 6.4 0.1 2.3 2 0 0 2 2 2 0 Ras family PDZ PF00595.24 EKX50832.1 - 2.3e-11 43.9 0.0 4.8e-06 26.8 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EKX50832.1 - 6.6e-09 35.5 0.0 0.00011 22.0 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX50832.1 - 1.9e-08 34.5 0.0 0.0076 16.6 0.0 2.7 2 0 0 2 2 2 2 PDZ domain DUF3370 PF11850.8 EKX50832.1 - 0.15 10.9 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3370) DEC-1_N PF04625.13 EKX50832.1 - 2.6 6.9 15.9 2.1 7.3 14.1 1.6 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region DUF4551 PF15087.6 EKX50835.1 - 0.58 8.9 3.1 0.81 8.4 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) VHS PF00790.19 EKX50836.1 - 8.8e-13 48.3 0.0 2.1e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 EKX50836.1 - 0.34 11.3 4.5 5 7.5 0.2 2.8 2 1 1 3 3 3 0 GAT domain TerB_C PF15615.6 EKX50837.1 - 0.092 13.0 8.4 0.13 12.6 0.9 3.0 2 0 0 2 2 2 0 TerB-C domain SlyX PF04102.12 EKX50837.1 - 4.2 8.1 12.9 8.5 7.1 0.4 4.5 4 0 0 4 4 4 0 SlyX JmjC PF02373.22 EKX50838.1 - 3.8e-37 127.2 0.0 5.4e-37 126.7 0.0 1.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase RRM_1 PF00076.22 EKX50840.1 - 5.3e-22 77.4 0.0 1.2e-21 76.3 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.6 EKX50840.1 - 4.8e-13 49.4 0.5 8.4e-13 48.6 0.5 1.3 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_7 PF16367.5 EKX50840.1 - 0.0022 18.0 0.0 0.0038 17.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif Spo7_2_N PF15407.6 EKX50840.1 - 0.027 14.1 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Sporulation protein family 7 RRM_Rrp7 PF17799.1 EKX50840.1 - 0.038 13.8 0.0 0.16 11.8 0.0 1.8 1 1 1 2 2 2 0 Rrp7 RRM-like N-terminal domain Methyltransf_11 PF08241.12 EKX50841.1 - 5.4e-07 30.2 0.0 1.6e-06 28.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX50841.1 - 3.5e-05 24.4 0.0 0.00014 22.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX50841.1 - 0.00028 20.7 0.0 0.002 18.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 EKX50841.1 - 0.0069 15.0 0.0 0.011 14.4 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_23 PF13489.6 EKX50841.1 - 0.0092 15.8 0.0 0.023 14.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Bin3 PF06859.12 EKX50841.1 - 0.0092 16.6 0.0 0.018 15.7 0.0 1.5 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_12 PF08242.12 EKX50841.1 - 0.03 15.1 0.0 0.056 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PTCB-BRCT PF12738.7 EKX50842.1 - 2.7e-08 33.6 0.1 7.2e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 EKX50842.1 - 5.5e-06 26.7 0.0 1.6e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EKX50842.1 - 0.00029 21.2 0.0 0.0006 20.2 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain EF-hand_7 PF13499.6 EKX50843.1 - 2.8e-14 53.3 0.2 2.5e-09 37.5 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX50843.1 - 4.5e-13 47.7 0.3 0.0006 19.2 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EKX50843.1 - 3.2e-11 42.9 0.1 0.0042 16.9 0.0 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EKX50843.1 - 4.9e-11 41.6 0.1 0.001 18.8 0.1 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 EKX50843.1 - 0.00012 21.4 0.2 1.5 8.4 0.0 3.5 3 0 0 3 3 3 1 EF hand EF-hand_10 PF14788.6 EKX50843.1 - 0.00019 21.3 0.1 0.015 15.1 0.0 2.6 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 EKX50843.1 - 0.00093 19.5 0.0 0.86 10.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain MotY_N PF18393.1 EKX50843.1 - 0.0013 18.9 0.4 0.02 15.0 0.2 2.1 1 1 1 2 2 2 1 MotY N-terminal domain p25-alpha PF05517.12 EKX50843.1 - 0.0037 17.5 0.2 2 8.5 0.0 2.2 1 1 1 2 2 2 2 p25-alpha FANCF PF11107.8 EKX50843.1 - 0.0068 15.7 0.9 0.2 10.8 0.3 2.1 2 0 0 2 2 2 1 Fanconi anemia group F protein (FANCF) DUF935 PF06074.12 EKX50843.1 - 0.0089 14.8 0.0 0.13 10.9 0.0 2.1 1 1 0 2 2 2 1 Protein of unknown function (DUF935) AAA_assoc_C PF09821.9 EKX50843.1 - 0.055 14.0 0.5 0.25 11.9 0.1 2.0 2 0 0 2 2 2 0 C-terminal AAA-associated domain FGAR-AT_linker PF18072.1 EKX50843.1 - 0.097 13.2 0.0 0.3 11.7 0.0 1.9 2 0 0 2 2 2 0 Formylglycinamide ribonucleotide amidotransferase linker domain Pup_ligase PF03136.15 EKX50843.1 - 1 8.3 4.5 0.69 8.9 0.6 2.0 1 1 1 2 2 2 0 Pup-ligase protein PKD_channel PF08016.12 EKX50845.1 - 1.4e-52 178.8 14.6 2.3e-52 178.1 14.6 1.3 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 EKX50845.1 - 1.7e-09 37.3 22.2 3.2e-09 36.4 22.2 1.5 1 0 0 1 1 1 1 Ion transport protein Abhydrolase_9_N PF15420.6 EKX50845.1 - 0.053 13.5 15.2 0.62 10.0 7.3 2.5 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus cNMP_binding PF00027.29 EKX50847.1 - 3.5e-08 33.4 0.1 8.2e-08 32.2 0.1 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain IQ PF00612.27 EKX50847.1 - 1.1e-05 24.8 3.6 0.0036 17.0 0.3 3.2 3 0 0 3 3 3 2 IQ calmodulin-binding motif SHE3 PF17078.5 EKX50848.1 - 3.2e-05 23.7 12.9 3.2e-05 23.7 12.9 8.1 3 2 3 7 7 7 2 SWI5-dependent HO expression protein 3 CENP-F_leu_zip PF10473.9 EKX50848.1 - 4.3e-05 23.6 6.9 4.3e-05 23.6 6.9 13.0 2 2 10 13 13 13 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0242 PF06785.11 EKX50848.1 - 0.00087 19.4 15.8 0.00087 19.4 15.8 11.8 2 1 7 9 9 9 3 Uncharacterised protein family (UPF0242) N-terminus GAS PF13851.6 EKX50848.1 - 0.005 16.2 7.0 0.005 16.2 7.0 11.7 2 1 8 12 12 12 5 Growth-arrest specific micro-tubule binding ATP-synt_ab_N PF02874.23 EKX50848.1 - 0.12 12.9 0.3 3.3 8.3 0.0 3.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, beta-barrel domain ATP_bind_2 PF03668.15 EKX50849.1 - 9.8e-25 87.4 0.0 1.2e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 P-loop ATPase protein family zf-RING_2 PF13639.6 EKX50850.1 - 2e-05 24.9 8.7 2e-05 24.9 8.7 6.5 5 2 1 6 6 6 1 Ring finger domain IBR PF01485.21 EKX50850.1 - 0.0023 18.1 5.3 0.0023 18.1 5.3 7.5 2 1 2 4 4 4 1 IBR domain, a half RING-finger domain C1_4 PF07975.12 EKX50850.1 - 0.003 17.8 7.3 0.003 17.8 7.3 6.4 4 3 2 6 6 6 1 TFIIH C1-like domain zf-RING_5 PF14634.6 EKX50850.1 - 0.017 15.1 5.8 0.017 15.1 5.8 7.4 4 3 0 4 4 4 0 zinc-RING finger domain LysM PF01476.20 EKX50852.1 - 2.1e-09 37.3 0.1 1e-06 28.7 0.0 2.9 2 1 0 2 2 2 2 LysM domain SNARE_assoc PF09335.11 EKX50855.1 - 6.2e-09 36.4 9.5 1.2e-08 35.5 6.0 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein TMEM169 PF15052.6 EKX50855.1 - 6.4 6.9 8.4 1.2 9.3 0.6 2.6 2 1 1 3 3 3 0 TMEM169 protein family CAP_C PF08603.11 EKX50856.1 - 5.1e-15 55.4 0.5 7.4e-15 54.9 0.5 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 EKX50856.1 - 0.0092 15.7 0.4 0.015 15.0 0.4 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C DivIC PF04977.15 EKX50856.1 - 0.023 14.4 0.2 0.067 13.0 0.1 1.8 2 0 0 2 2 2 0 Septum formation initiator FlaC_arch PF05377.11 EKX50856.1 - 7.4 7.0 7.5 0.29 11.6 1.6 1.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) MORN PF02493.20 EKX50858.1 - 5.9e-54 176.8 74.9 1.8e-07 30.6 1.8 11.6 11 1 0 11 11 11 10 MORN repeat Asp_Arg_Hydrox PF05118.15 EKX50859.1 - 7.6e-42 142.8 0.0 1.1e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Raptor_N PF14538.6 EKX50859.1 - 0.0025 17.8 0.0 0.0045 17.0 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HJURP_C PF12347.8 EKX50859.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat Ubiquitin_4 PF18036.1 EKX50859.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain TPR_12 PF13424.6 EKX50861.1 - 9e-10 38.7 7.2 0.0019 18.4 0.1 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX50861.1 - 1e-07 31.7 1.7 0.017 14.5 0.0 2.6 2 0 0 2 2 2 2 MalT-like TPR region TPR_14 PF13428.6 EKX50861.1 - 5.6e-05 23.6 4.0 0.088 13.7 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX50861.1 - 0.00034 20.6 0.2 0.012 15.7 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX50861.1 - 0.00037 20.3 0.1 0.043 13.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX50861.1 - 0.00037 20.2 0.1 0.003 17.3 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX50861.1 - 0.00079 19.4 6.0 0.0032 17.5 0.1 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX50861.1 - 0.0047 16.7 0.9 2.8 7.9 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX50861.1 - 0.045 14.4 0.1 0.22 12.2 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX50861.1 - 0.095 13.2 0.2 1.1 9.9 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat MtN3_slv PF03083.16 EKX50862.1 - 1.3e-22 79.6 9.6 9.9e-16 57.6 3.0 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange MTABC_N PF16185.5 EKX50862.1 - 0.0016 18.0 0.2 0.0023 17.5 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial ABC-transporter N-terminal five TM region LAB_N PF07578.11 EKX50862.1 - 0.03 14.4 0.7 3.7 7.7 0.2 2.5 2 1 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain DNA_pol_B PF00136.21 EKX50865.1 - 5.8e-96 322.0 0.0 7.4e-96 321.6 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.6 EKX50865.1 - 6.7e-09 36.1 10.2 6.7e-09 36.1 10.2 2.0 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DUF2946 PF11162.8 EKX50865.1 - 0.073 13.7 0.1 0.18 12.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Redoxin PF08534.10 EKX50867.1 - 3.8e-05 23.4 0.0 5.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EKX50867.1 - 0.0011 18.9 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EKX50867.1 - 0.0039 17.5 0.0 0.0077 16.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_10 PF17991.1 EKX50867.1 - 0.032 14.8 0.0 1.1 9.9 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin like C-terminal domain GNT-I PF03071.15 EKX50867.1 - 0.17 10.6 0.1 0.26 10.0 0.1 1.2 1 0 0 1 1 1 0 GNT-I family LSM PF01423.22 EKX50868.1 - 6.1e-19 67.5 0.3 7.6e-19 67.2 0.3 1.1 1 0 0 1 1 1 1 LSM domain Acetyltransf_1 PF00583.25 EKX50869.1 - 3.3e-10 40.2 0.0 6.6e-08 32.8 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EKX50869.1 - 8.5e-09 35.7 0.0 1.7e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EKX50869.1 - 7.5e-07 29.1 0.0 0.00022 21.2 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EKX50869.1 - 1.1e-05 25.3 0.1 0.015 15.2 0.0 3.0 4 0 0 4 4 4 2 FR47-like protein Acetyltransf_3 PF13302.7 EKX50869.1 - 0.072 13.8 0.0 0.12 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SufE PF02657.15 EKX50870.1 - 1.8e-37 127.9 0.0 2.1e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 Fe-S metabolism associated domain DUF4928 PF16280.5 EKX50870.1 - 0.066 12.5 0.0 0.15 11.3 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4928) NAD_binding_10 PF13460.6 EKX50871.1 - 2.3e-37 128.6 0.6 3e-37 128.3 0.6 1.1 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EKX50871.1 - 1.8e-06 27.5 2.3 6.3e-06 25.8 0.7 2.1 1 1 1 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 EKX50871.1 - 4.8e-05 23.0 0.1 6.7e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EKX50871.1 - 6.4e-05 22.1 1.5 9e-05 21.6 1.5 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EKX50871.1 - 0.00034 20.1 0.1 0.00074 19.1 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HIM1 PF08732.10 EKX50871.1 - 0.0075 15.8 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 HIM1 TrkA_N PF02254.18 EKX50871.1 - 0.021 15.1 0.3 0.04 14.2 0.3 1.5 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 EKX50871.1 - 0.023 14.0 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EKX50871.1 - 0.036 14.7 1.4 0.1 13.2 0.2 2.1 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_4 PF07993.12 EKX50871.1 - 0.044 13.0 0.0 0.31 10.1 0.0 2.0 2 0 0 2 2 2 0 Male sterility protein adh_short_C2 PF13561.6 EKX50871.1 - 0.045 13.3 2.6 0.13 11.8 0.4 2.1 1 1 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase zf-C2HC5 PF06221.13 EKX50872.1 - 0.027 14.4 0.1 0.036 14.1 0.1 1.2 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type P_proprotein PF01483.20 EKX50873.1 - 0.094 12.8 0.0 0.33 11.0 0.0 1.9 1 0 0 1 1 1 0 Proprotein convertase P-domain NDC10_II PF16787.5 EKX50878.1 - 0.059 12.4 0.0 0.065 12.3 0.0 1.1 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Pkinase PF00069.25 EKX50879.1 - 3.5e-44 151.2 0.0 4.5e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX50879.1 - 1.8e-43 148.7 0.0 4.3e-43 147.5 0.0 1.4 1 1 1 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EKX50879.1 - 2.8e-06 26.5 0.0 4.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EKX50879.1 - 0.0038 17.2 0.0 0.0072 16.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX50879.1 - 0.0093 14.8 0.0 0.013 14.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Coilin_N PF15862.5 EKX50881.1 - 1.2e-05 25.1 0.0 0.00025 20.9 0.0 2.3 1 1 1 2 2 2 1 Coilin N-terminus TFIIA PF03153.13 EKX50881.1 - 0.00013 22.1 21.6 0.00016 21.8 21.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 EKX50881.1 - 0.42 10.7 8.1 0.62 10.2 8.1 1.4 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 EKX50881.1 - 0.53 9.0 13.1 0.7 8.6 13.1 1.2 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 EKX50881.1 - 0.84 9.2 30.2 1.4 8.5 30.2 1.3 1 0 0 1 1 1 0 Spt20 family GREB1 PF15782.5 EKX50881.1 - 0.86 6.6 10.0 0.95 6.5 10.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Roughex PF06020.11 EKX50881.1 - 1.5 7.9 11.2 2.1 7.4 11.2 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Neur_chan_memb PF02932.16 EKX50881.1 - 2.6 8.1 10.3 3.5 7.6 10.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Androgen_recep PF02166.16 EKX50881.1 - 3.9 6.2 20.0 5.8 5.6 20.0 1.3 1 0 0 1 1 1 0 Androgen receptor eIF-3_zeta PF05091.12 EKX50881.1 - 4.1 6.3 17.3 5.9 5.7 17.3 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MTBP_C PF14920.6 EKX50881.1 - 6.1 6.5 14.7 7.2 6.3 13.5 1.7 2 0 0 2 2 2 0 MDM2-binding Ax_dynein_light PF10211.9 EKX50881.1 - 7.1 6.5 16.1 3 7.7 13.6 1.6 1 1 0 1 1 1 0 Axonemal dynein light chain V_ATPase_I PF01496.19 EKX50881.1 - 9.9 3.9 9.4 12 3.7 9.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADK PF00406.22 EKX50882.1 - 2.5e-42 144.5 0.0 2.9e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EKX50882.1 - 2e-24 86.5 0.3 3.7e-24 85.7 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EKX50882.1 - 2.2e-08 34.7 0.1 8.8e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EKX50882.1 - 0.0004 20.6 0.1 0.0054 16.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EKX50882.1 - 0.00046 20.6 0.0 0.00074 19.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EKX50882.1 - 0.0006 20.1 0.1 0.0011 19.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EKX50882.1 - 0.00099 18.4 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.17 EKX50882.1 - 0.0014 18.3 0.1 0.099 12.3 0.0 2.8 3 0 0 3 3 3 1 Thymidylate kinase CoaE PF01121.20 EKX50882.1 - 0.0019 17.9 0.1 0.0032 17.1 0.1 1.6 1 1 0 1 1 1 1 Dephospho-CoA kinase DUF815 PF05673.13 EKX50882.1 - 0.011 15.0 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Cytidylate_kin2 PF13189.6 EKX50882.1 - 0.021 15.0 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase-like family Cytidylate_kin PF02224.18 EKX50882.1 - 0.025 14.3 0.4 0.13 12.0 0.0 2.0 2 1 0 2 2 2 0 Cytidylate kinase ABC_tran PF00005.27 EKX50882.1 - 0.036 14.6 0.1 0.041 14.4 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 EKX50882.1 - 0.068 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EKX50882.1 - 0.072 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 NTPase Hydin_ADK PF17213.3 EKX50882.1 - 0.09 13.0 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Viral_helicase1 PF01443.18 EKX50882.1 - 0.14 11.8 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 EKX50882.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain TPR_17 PF13431.6 EKX50883.1 - 8.8e-35 116.6 2.5 2.3e-05 24.4 0.1 9.0 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_11 PF13414.6 EKX50883.1 - 3.3e-29 100.3 6.8 3.9e-06 26.4 0.0 9.0 5 3 4 9 9 9 7 TPR repeat TPR_2 PF07719.17 EKX50883.1 - 8.1e-27 91.2 14.0 7.7e-05 22.5 0.0 7.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 EKX50883.1 - 1.4e-26 90.9 5.0 4e-05 24.1 0.5 8.4 4 3 5 9 9 9 5 Tetratricopeptide repeat TPR_19 PF14559.6 EKX50883.1 - 2.7e-23 82.2 3.4 1.4e-05 25.5 0.3 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EKX50883.1 - 8.6e-22 75.5 2.9 0.00063 19.8 0.0 6.5 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_16 PF13432.6 EKX50883.1 - 6.3e-19 68.3 4.7 2.8e-07 31.1 2.3 5.1 3 1 3 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 EKX50883.1 - 8.1e-19 66.6 20.4 0.0029 17.4 0.0 8.5 10 1 0 10 10 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 EKX50883.1 - 2.9e-18 65.9 7.0 0.0012 19.1 0.5 7.2 4 1 5 9 9 8 7 Tetratricopeptide repeat TPR_7 PF13176.6 EKX50883.1 - 8e-14 50.6 1.7 0.2 11.7 0.0 7.9 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 EKX50883.1 - 1.6e-09 37.8 1.2 0.0031 17.6 1.5 4.6 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 EKX50883.1 - 1.5e-08 34.2 0.2 0.21 10.8 0.0 3.9 2 2 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 EKX50883.1 - 8.5e-07 29.2 2.6 2.3 9.0 0.1 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TOM20_plant PF06552.12 EKX50883.1 - 1.1e-05 25.3 0.6 0.0035 17.1 0.0 3.5 3 1 1 4 4 4 1 Plant specific mitochondrial import receptor subunit TOM20 Coatomer_E PF04733.14 EKX50883.1 - 1.1e-05 25.0 0.3 0.81 9.0 0.0 3.6 2 1 1 3 3 3 2 Coatomer epsilon subunit ANAPC3 PF12895.7 EKX50883.1 - 2.7e-05 24.3 1.5 0.38 11.0 0.3 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EKX50883.1 - 5.6e-05 22.9 15.8 0.34 10.8 0.2 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX50883.1 - 0.00022 21.2 0.5 6.5 6.9 0.0 3.8 4 0 0 4 4 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_MalT PF17874.1 EKX50883.1 - 0.00027 20.4 0.0 2.9 7.2 0.0 3.4 3 0 0 3 3 3 1 MalT-like TPR region DUF3808 PF10300.9 EKX50883.1 - 0.0077 15.0 0.1 0.57 8.9 0.0 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF3808) NARP1 PF12569.8 EKX50883.1 - 0.012 14.6 0.0 0.012 14.6 0.0 3.6 3 1 0 4 4 4 0 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 EKX50883.1 - 0.16 12.3 5.0 3.2 8.2 0.2 4.2 3 2 1 5 5 5 0 Tetratricopeptide repeat SNF2_N PF00176.23 EKX50884.1 - 5.7e-45 153.6 0.0 6.6e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 EKX50884.1 - 0.001 18.9 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EKX50884.1 - 0.049 13.3 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 SWI2/SNF2 ATPase zf-C3HC4_3 PF13920.6 EKX50885.1 - 8.6e-07 28.7 14.2 2e-06 27.5 14.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ATG16 PF08614.11 EKX50885.1 - 0.012 15.8 14.5 0.012 15.8 14.5 4.9 2 1 1 4 4 4 0 Autophagy protein 16 (ATG16) Prok-RING_4 PF14447.6 EKX50885.1 - 0.76 9.7 15.3 1.6 8.7 15.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PMEI PF04043.15 EKX50885.1 - 0.78 10.1 17.8 0.19 12.1 0.5 3.4 3 1 1 4 4 4 0 Plant invertase/pectin methylesterase inhibitor zf-RING_2 PF13639.6 EKX50885.1 - 2.2 8.7 17.7 6.6 7.2 17.7 1.9 1 0 0 1 1 1 0 Ring finger domain FlaC_arch PF05377.11 EKX50885.1 - 2.4 8.6 19.5 0.72 10.3 0.3 4.9 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) DHquinase_I PF01487.15 EKX50886.1 - 6.9e-16 59.2 0.0 1.3e-15 58.3 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase Trypsin PF00089.26 EKX50888.1 - 3.8e-36 125.0 2.3 4.6e-36 124.7 2.3 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 EKX50888.1 - 0.00024 22.1 0.1 0.00035 21.5 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF1986 PF09342.11 EKX50888.1 - 0.00051 20.4 0.2 0.0012 19.3 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1986) THUMP PF02926.17 EKX50890.1 - 9.4e-14 51.7 0.7 1.8e-13 50.8 0.5 1.7 1 1 0 1 1 1 1 THUMP domain PAT1 PF09770.9 EKX50891.1 - 0.16 10.2 45.4 0.23 9.7 45.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 EKX50891.1 - 0.2 8.8 35.3 0.27 8.3 35.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SOBP PF15279.6 EKX50891.1 - 2.3 8.8 26.0 4.4 7.8 26.0 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Fz PF01392.22 EKX50892.1 - 6.5e-06 26.7 1.7 8.8e-06 26.3 0.5 1.8 2 0 0 2 2 2 1 Fz domain TPR_16 PF13432.6 EKX50892.1 - 0.12 13.0 0.4 0.45 11.2 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Pro_isomerase PF00160.21 EKX50893.1 - 5.5e-16 59.2 0.5 7.3e-16 58.8 0.5 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF179 PF02622.15 EKX50894.1 - 2.3e-22 79.7 0.0 3.5e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 TolA_bind_tri PF16331.5 EKX50895.1 - 0.11 12.6 7.1 0.15 12.2 2.6 2.6 2 0 0 2 2 2 0 TolA binding protein trimerisation EF-hand_1 PF00036.32 EKX50898.1 - 3.5e-16 57.4 1.1 6.2e-07 28.5 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EKX50898.1 - 2.6e-13 48.8 0.9 3.9e-06 26.1 0.2 2.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX50898.1 - 1.9e-12 46.8 5.5 6.1e-09 35.6 1.2 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX50898.1 - 2.1e-12 45.9 0.3 6.3e-06 25.7 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EKX50898.1 - 7e-12 45.6 0.2 8.8e-12 45.3 0.2 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_4 PF12763.7 EKX50898.1 - 5e-05 23.2 0.6 0.057 13.4 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SHOCT PF09851.9 EKX50898.1 - 5.7e-05 22.7 1.8 0.061 13.1 0.3 3.3 3 0 0 3 3 3 2 Short C-terminal domain EF-hand_9 PF14658.6 EKX50898.1 - 0.043 14.1 0.0 0.057 13.8 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain SPARC_Ca_bdg PF10591.9 EKX50898.1 - 0.096 13.0 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Pox_E10 PF04805.12 EKX50898.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 E10-like protein conserved region LRR_6 PF13516.6 EKX50899.1 - 6.8e-26 88.1 18.9 2e-05 24.3 0.1 6.9 7 0 0 7 7 7 6 Leucine Rich repeat LRR_4 PF12799.7 EKX50899.1 - 6.3e-07 29.6 13.6 0.16 12.5 0.0 5.0 4 1 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX50899.1 - 7e-05 22.8 3.2 21 6.2 0.6 6.1 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.6 EKX50899.1 - 0.00026 20.7 17.4 0.53 10.1 4.2 5.8 2 2 1 4 4 4 4 Leucine rich repeat RWP-RK PF02042.15 EKX50900.1 - 1.4e-08 34.6 0.0 2.7e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain Band_7 PF01145.25 EKX50901.1 - 8.8e-29 100.8 1.7 1.1e-28 100.4 0.8 1.6 1 1 1 2 2 2 1 SPFH domain / Band 7 family COMM_domain PF07258.14 EKX50902.1 - 5.8e-14 52.0 0.0 8.7e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 COMM domain BHD_1 PF10403.9 EKX50903.1 - 8.8e-16 57.5 0.1 1.8e-15 56.5 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_3 PF10405.9 EKX50903.1 - 9.9e-14 51.5 0.0 3.3e-13 49.8 0.0 1.8 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 EKX50903.1 - 1.4e-12 47.5 8.7 1.4e-12 47.5 8.7 3.0 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_2 PF10404.9 EKX50903.1 - 2.1e-05 25.3 1.5 2.1e-05 25.3 1.5 6.0 5 2 0 5 5 5 1 Rad4 beta-hairpin domain 2 Peptidase_U32 PF01136.19 EKX50903.1 - 0.85 8.7 5.5 0.56 9.3 2.3 2.2 2 0 0 2 2 2 0 Peptidase family U32 SOG2 PF10428.9 EKX50903.1 - 1.5 8.0 8.7 0.68 9.1 4.2 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein ALMT PF11744.8 EKX50903.1 - 4.1 6.1 9.5 15 4.2 9.5 1.9 1 0 0 1 1 1 0 Aluminium activated malate transporter LRR_6 PF13516.6 EKX50904.1 - 7.5e-48 156.6 71.9 1.1e-06 28.2 0.3 18.2 17 1 1 18 18 18 17 Leucine Rich repeat LRR_4 PF12799.7 EKX50904.1 - 1.4e-17 63.5 42.4 0.023 15.1 5.7 11.3 4 3 9 14 14 14 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX50904.1 - 2.2e-08 33.7 43.4 0.032 14.0 7.0 11.3 6 4 3 9 9 9 4 Leucine rich repeat LRR_1 PF00560.33 EKX50904.1 - 7.8e-07 28.8 36.3 9.8 7.2 0.0 13.0 15 1 0 15 15 15 3 Leucine Rich Repeat JmjC PF02373.22 EKX50905.1 - 1.4e-09 38.4 0.0 3.3e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 EKX50905.1 - 0.0028 17.6 0.0 0.008 16.1 0.0 1.8 2 0 0 2 2 2 1 jmjN domain V_ATPase_I PF01496.19 EKX50906.1 - 0.049 11.5 0.4 0.065 11.2 0.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Astro_capsid_p PF12226.8 EKX50906.1 - 0.1 11.7 14.9 0.12 11.5 14.9 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein BUD22 PF09073.10 EKX50906.1 - 0.65 9.3 18.9 0.72 9.1 18.9 1.1 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 EKX50906.1 - 1.8 8.1 25.0 2.5 7.6 25.0 1.2 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.12 EKX50906.1 - 3.4 6.9 28.0 4.7 6.4 28.0 1.2 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 EKX50906.1 - 5.1 6.4 23.3 5.6 6.3 23.3 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 EKX50906.1 - 5.7 5.1 18.0 7.2 4.8 18.0 1.2 1 0 0 1 1 1 0 CDC45-like protein ATG16 PF08614.11 EKX50908.1 - 0.003 17.8 8.4 0.0055 17.0 8.4 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ATPase PF06745.13 EKX50908.1 - 0.0037 16.6 6.2 0.079 12.3 0.0 2.3 2 0 0 2 2 2 1 KaiC DUF4349 PF14257.6 EKX50908.1 - 0.012 15.1 7.5 0.024 14.1 7.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) RHSP PF07999.11 EKX50908.1 - 0.023 13.5 0.6 0.092 11.5 0.0 2.0 2 0 0 2 2 2 0 Retrotransposon hot spot protein CobN-Mg_chel PF02514.16 EKX50908.1 - 0.045 11.5 0.9 0.076 10.7 0.9 1.3 1 0 0 1 1 1 0 CobN/Magnesium Chelatase HemX PF04375.14 EKX50908.1 - 0.074 12.3 6.3 0.16 11.3 6.3 1.4 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase AAA_16 PF13191.6 EKX50908.1 - 0.14 12.5 0.1 1.2 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 EKX50908.1 - 0.18 12.2 0.0 0.64 10.4 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Baculo_PEP_C PF04513.12 EKX50908.1 - 0.38 10.8 2.9 0.84 9.7 2.9 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.19 EKX50908.1 - 0.38 8.6 2.2 0.55 8.1 2.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 EKX50908.1 - 0.41 11.2 14.4 0.033 14.7 8.8 2.0 2 0 0 2 2 1 0 Apg6 coiled-coil region SPT16 PF08644.11 EKX50908.1 - 0.54 10.4 6.2 1.3 9.2 6.2 1.5 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) ADIP PF11559.8 EKX50908.1 - 0.66 10.0 11.8 1.3 9.1 11.8 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding RmuC PF02646.16 EKX50908.1 - 0.71 8.9 9.7 1.4 8.0 9.7 1.3 1 0 0 1 1 1 0 RmuC family Tho2 PF11262.8 EKX50908.1 - 0.86 8.7 3.8 1.5 8.0 3.8 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Nup88 PF10168.9 EKX50908.1 - 0.98 7.2 6.2 1.4 6.6 6.2 1.1 1 0 0 1 1 1 0 Nuclear pore component FapA PF03961.13 EKX50908.1 - 1.1 7.8 10.0 1.7 7.2 10.0 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A NPV_P10 PF05531.12 EKX50908.1 - 3.4 8.2 6.7 7.3 7.1 4.2 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.6 EKX50908.1 - 8.4 4.9 8.7 16 4.0 8.7 1.3 1 0 0 1 1 1 0 AAA domain DUF3552 PF12072.8 EKX50908.1 - 9 5.7 18.5 17 4.8 18.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) AAA_23 PF13476.6 EKX50908.1 - 9.6 6.6 13.3 15 6.0 11.8 2.1 3 0 0 3 3 2 0 AAA domain THAP PF05485.12 EKX50909.1 - 0.017 16.0 0.2 0.073 14.0 0.2 2.1 1 0 0 1 1 1 0 THAP domain Zn-C2H2_12 PF18112.1 EKX50910.1 - 0.0015 19.0 0.3 0.0035 17.8 0.3 1.6 1 0 0 1 1 1 1 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_4 PF13894.6 EKX50910.1 - 0.43 11.5 7.4 1.2 10.2 0.3 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger ANAPC_CDC26 PF10471.9 EKX50913.1 - 0.61 11.0 4.5 2.2 9.2 4.5 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Jak1_Phl PF17887.1 EKX50913.1 - 1.2 9.1 6.9 3.2 7.7 6.9 1.7 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain Peptidase_S49_N PF08496.10 EKX50913.1 - 4.3 7.4 7.5 16 5.5 7.5 2.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1764 PF08576.10 EKX50913.1 - 7.9 7.4 14.6 12 6.9 8.9 3.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Tmemb_14 PF03647.13 EKX50914.1 - 1.5e-16 60.9 11.5 1.5e-16 60.9 11.5 1.8 2 0 0 2 2 2 1 Transmembrane proteins 14C CPP1-like PF11833.8 EKX50914.1 - 2.3 7.8 8.6 0.25 11.0 3.0 1.9 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Coa1 PF08695.10 EKX50915.1 - 3.2e-08 33.3 0.1 8.8e-08 31.9 0.0 1.8 2 0 0 2 2 2 1 Cytochrome oxidase complex assembly protein 1 UPF0154 PF03672.13 EKX50915.1 - 0.17 11.9 0.1 0.34 11.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Epimerase PF01370.21 EKX50916.1 - 4.4e-19 68.9 0.0 5.8e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EKX50916.1 - 2.5e-18 66.1 0.0 3e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EKX50916.1 - 5.1e-09 35.7 0.0 4.8e-07 29.2 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EKX50916.1 - 7.8e-09 35.7 0.0 1.5e-08 34.8 0.0 1.4 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EKX50916.1 - 3.8e-07 29.9 0.0 0.00014 21.5 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family GDP_Man_Dehyd PF16363.5 EKX50916.1 - 6.3e-06 25.8 0.0 8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EKX50916.1 - 0.0052 15.9 0.0 0.027 13.6 0.0 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EKX50916.1 - 0.036 13.2 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.10 EKX50916.1 - 0.12 12.3 0.0 1.5 8.7 0.0 2.0 2 0 0 2 2 2 0 KR domain adh_short PF00106.25 EKX50916.1 - 0.19 11.1 0.0 0.37 10.2 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase UDPG_MGDP_dh_N PF03721.14 EKX50916.1 - 0.21 11.1 0.2 0.56 9.7 0.2 1.8 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SWIM PF04434.17 EKX50917.1 - 1.6e-06 27.6 0.1 4.1e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 SWIM zinc finger zf-CCHC_2 PF13696.6 EKX50917.1 - 0.18 11.6 1.3 0.5 10.2 1.3 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 EKX50917.1 - 0.19 11.9 2.3 0.41 10.8 2.3 1.6 1 0 0 1 1 1 0 Zinc knuckle FtsJ PF01728.19 EKX50918.1 - 3.6e-46 157.5 0.1 4.3e-46 157.3 0.1 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase XG_FTase PF03254.13 EKX50920.1 - 1.8e-10 40.1 0.0 6.3e-06 25.1 0.0 2.4 2 0 0 2 2 2 2 Xyloglucan fucosyltransferase TehB PF03848.14 EKX50920.1 - 0.0011 18.4 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_15 PF09445.10 EKX50920.1 - 0.074 12.6 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MMR_HSR1 PF01926.23 EKX50921.1 - 2.5e-17 63.0 0.1 1.9e-14 53.7 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EKX50921.1 - 4.2e-08 32.9 0.1 3e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EKX50921.1 - 1.3e-07 31.3 0.6 0.0023 17.5 0.0 2.9 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EKX50921.1 - 1.4e-06 28.3 1.5 0.0095 15.9 0.2 2.3 1 1 1 2 2 2 2 RsgA GTPase AIG1 PF04548.16 EKX50921.1 - 5.3e-05 22.6 0.2 0.00044 19.6 0.1 2.2 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 EKX50921.1 - 0.00032 20.8 1.4 0.043 13.9 0.1 3.1 2 1 1 3 3 3 1 Dynamin family Roc PF08477.13 EKX50921.1 - 0.0043 17.2 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1_Xtn PF16897.5 EKX50921.1 - 0.01 15.8 0.1 0.022 14.8 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain MeaB PF03308.16 EKX50921.1 - 0.014 14.4 0.2 0.027 13.4 0.2 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EKX50921.1 - 0.031 14.7 0.0 0.045 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.12 EKX50921.1 - 0.14 11.5 0.2 2.9 7.2 0.1 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EKX50921.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Kelch_3 PF13415.6 EKX50922.1 - 2.5e-08 34.0 0.9 7.7e-05 22.9 0.1 4.5 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_6 PF13964.6 EKX50922.1 - 2.1e-07 31.0 1.1 0.0057 16.9 0.1 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 EKX50922.1 - 6.5e-07 29.3 0.4 5.7e-05 23.0 0.6 3.0 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.6 EKX50922.1 - 0.00018 21.4 0.0 0.0039 17.1 0.1 2.8 2 0 0 2 2 2 1 Kelch motif MIB_HERC2 PF06701.13 EKX50922.1 - 0.027 14.7 1.6 0.062 13.6 0.3 2.1 2 0 0 2 2 2 0 Mib_herc2 Kelch_1 PF01344.25 EKX50922.1 - 0.091 12.4 1.0 0.44 10.2 0.1 2.4 2 0 0 2 2 2 0 Kelch motif Exo_endo_phos PF03372.23 EKX50923.1 - 4.7e-06 26.3 0.0 1e-05 25.2 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Syntaxin_2 PF14523.6 EKX50924.1 - 0.082 13.3 6.6 0.052 13.9 3.7 2.0 2 0 0 2 2 2 0 Syntaxin-like protein Pox_A_type_inc PF04508.12 EKX50924.1 - 0.35 10.8 6.7 0.46 10.4 0.7 3.8 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat IFP_35_N PF07334.13 EKX50924.1 - 0.85 9.7 5.8 14 5.8 0.7 2.8 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Prominin PF05478.11 EKX50924.1 - 1.4 6.7 5.4 1.8 6.5 5.4 1.2 1 0 0 1 1 1 0 Prominin Apt1 PF10351.9 EKX50924.1 - 6.1 5.6 9.1 2.3 7.0 6.5 1.5 1 1 0 1 1 1 0 Golgi-body localisation protein domain bZIP_2 PF07716.15 EKX50924.1 - 7.8 6.7 17.0 1.1 9.4 1.3 4.8 3 1 1 4 4 4 0 Basic region leucine zipper Ank_5 PF13857.6 EKX50925.1 - 2.6e-11 43.5 1.7 4.3e-08 33.3 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX50925.1 - 3e-11 43.2 0.3 6.7e-05 23.1 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EKX50925.1 - 3.7e-11 42.2 0.1 3.8e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EKX50925.1 - 5.2e-10 39.8 0.1 2e-09 37.9 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX50925.1 - 7e-07 29.7 0.1 7.6e-06 26.4 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) EF-hand_8 PF13833.6 EKX50926.1 - 9.7e-14 51.0 2.1 2.5e-08 33.6 0.8 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX50926.1 - 4.2e-11 41.6 1.3 0.00033 20.0 0.5 3.0 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX50926.1 - 1.2e-10 40.5 0.1 0.0001 21.9 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EKX50926.1 - 2e-09 36.5 0.9 1.7e-05 24.1 0.1 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX50926.1 - 5.4e-09 36.4 0.3 5.4e-09 36.4 0.3 2.5 2 2 0 2 2 2 1 EF-hand domain pair Ferritin_2 PF13668.6 EKX50926.1 - 0.19 12.0 1.0 3.4 7.9 1.0 2.3 1 1 0 1 1 1 0 Ferritin-like domain SPARC_Ca_bdg PF10591.9 EKX50926.1 - 0.34 11.3 2.6 0.4 11.0 0.0 2.3 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region RhoGAP PF00620.27 EKX50927.1 - 1.6e-33 115.7 0.4 2.3e-33 115.2 0.4 1.2 1 0 0 1 1 1 1 RhoGAP domain BcrAD_BadFG PF01869.20 EKX50927.1 - 0.06 12.8 0.2 0.41 10.1 0.0 2.0 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Dymeclin PF09742.9 EKX50929.1 - 2.7e-32 112.0 1.1 5.9e-32 110.9 1.1 1.4 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Phospholip_B PF04916.13 EKX50929.1 - 0.0029 16.3 0.1 0.0039 15.8 0.1 1.1 1 0 0 1 1 1 1 Phospholipase B DUF167 PF02594.16 EKX50930.1 - 1.1e-20 73.5 0.3 2.6e-20 72.3 0.3 1.7 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 RWD PF05773.22 EKX50930.1 - 1e-07 32.2 0.0 3.2e-07 30.6 0.0 1.9 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 EKX50930.1 - 4.3e-07 30.1 12.0 5.8e-06 26.5 11.9 2.3 1 1 1 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 EKX50930.1 - 2e-06 27.7 8.4 6.2e-06 26.1 8.4 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 EKX50930.1 - 4.8e-06 26.2 8.6 4.8e-06 26.2 8.6 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 EKX50930.1 - 0.00026 21.2 6.0 0.00067 19.9 2.5 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EKX50930.1 - 0.00063 19.7 3.1 0.00063 19.7 3.1 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EKX50930.1 - 0.0038 17.2 0.9 0.0038 17.2 0.9 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 EKX50930.1 - 0.0056 16.5 3.2 0.0056 16.5 3.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EKX50930.1 - 0.093 12.6 10.4 0.025 14.4 4.9 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CTU2 PF10288.9 EKX50930.1 - 0.19 12.0 8.3 0.21 11.8 1.5 2.6 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-C3HC4_3 PF13920.6 EKX50930.1 - 0.43 10.5 7.7 2.9 7.8 0.3 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) IFP_35_N PF07334.13 EKX50930.1 - 0.57 10.3 3.3 2.3 8.3 3.3 2.1 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Zn_ribbon_17 PF17120.5 EKX50930.1 - 1.1 8.9 8.3 0.078 12.6 3.2 1.7 2 0 0 2 2 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EKX50930.1 - 2.3 8.5 7.1 0.4 10.9 1.8 2.3 3 0 0 3 3 2 0 FANCL C-terminal domain Prok-RING_1 PF14446.6 EKX50930.1 - 4 7.4 7.7 17 5.4 4.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF4337 PF14235.6 EKX50930.1 - 6.3 6.9 8.3 27 4.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) ATP-synt_DE_N PF02823.16 EKX50931.1 - 5.9e-18 64.6 0.2 1.9e-17 62.9 0.0 1.8 2 0 0 2 2 2 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_DE PF00401.20 EKX50931.1 - 0.025 14.8 0.4 0.025 14.8 0.4 1.6 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain TPR_11 PF13414.6 EKX50932.1 - 0.0019 17.8 0.0 0.017 14.8 0.0 2.3 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 EKX50932.1 - 0.012 15.7 0.0 0.046 13.9 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 EKX50932.1 - 0.13 12.9 1.7 0.24 12.1 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat CHZ PF09649.10 EKX50937.1 - 0.001 18.5 1.0 0.0025 17.3 1.0 1.7 1 0 0 1 1 1 1 Histone chaperone domain CHZ Linker_histone PF00538.19 EKX50937.1 - 0.12 12.8 1.8 7 7.1 1.8 2.7 1 1 0 1 1 1 0 linker histone H1 and H5 family NARP1 PF12569.8 EKX50937.1 - 1.1 8.1 18.5 2.4 7.0 18.0 1.7 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 DUF2828 PF11443.8 EKX50937.1 - 1.6 6.8 10.6 2 6.4 10.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Presenilin PF01080.17 EKX50937.1 - 1.9 7.2 8.0 2.1 7.0 8.0 1.2 1 0 0 1 1 1 0 Presenilin AAA_11 PF13086.6 EKX50937.1 - 3.1 7.5 12.7 5 6.8 12.7 1.3 1 0 0 1 1 1 0 AAA domain ALMT PF11744.8 EKX50937.1 - 8.9 5.0 11.0 12 4.6 11.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Ribonuc_L-PSP PF01042.21 EKX50938.1 - 9.9e-21 74.0 0.0 1.2e-20 73.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP NCA2 PF08637.10 EKX50938.1 - 0.01 15.0 0.0 1.9 7.6 0.0 2.0 1 1 1 2 2 2 0 ATP synthase regulation protein NCA2 Glyco_hydro_77 PF02446.17 EKX50939.1 - 1.8e-117 393.1 0.1 2.2e-117 392.8 0.1 1.0 1 0 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.19 EKX50939.1 - 9.7e-08 31.8 0.0 8.3e-05 22.4 0.0 2.8 2 0 0 2 2 2 2 Starch binding domain CheX PF13690.6 EKX50940.1 - 0.48 10.6 4.0 0.18 12.0 0.4 2.2 2 0 0 2 2 2 0 Chemotaxis phosphatase CheX NIF PF03031.18 EKX50943.1 - 2.4e-09 37.1 0.0 4.3e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.26 EKX50943.1 - 0.037 14.3 0.0 0.095 13.0 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase PDZ_6 PF17820.1 EKX50944.1 - 0.00091 19.0 0.0 0.14 12.0 0.0 2.9 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX50944.1 - 0.003 17.9 0.0 0.01 16.2 0.0 1.9 1 0 0 1 1 1 1 PDZ domain NTP_transf_7 PF07984.12 EKX50945.1 - 1.9e-09 37.2 0.0 2.9e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyltransferase DUF4336 PF14234.6 EKX50947.1 - 9.7e-24 84.1 0.2 3.8e-23 82.2 0.2 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4336) DUF5068 PF16781.5 EKX50947.1 - 0.088 12.6 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5068) PAP_assoc PF03828.19 EKX50948.1 - 1.1e-18 67.1 0.1 2.6e-18 66.0 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase PAP_central PF04928.17 EKX50948.1 - 0.021 13.8 0.0 0.049 12.6 0.0 1.5 2 0 0 2 2 2 0 Poly(A) polymerase central domain ILVD_EDD PF00920.21 EKX50949.1 - 7.2e-211 701.3 2.3 8.2e-211 701.1 2.3 1.0 1 0 0 1 1 1 1 Dehydratase family FeoA PF04023.14 EKX50949.1 - 0.021 15.1 0.1 6.2 7.2 0.0 2.7 2 0 0 2 2 2 0 FeoA domain RBP_receptor PF14752.6 EKX50950.1 - 5.5e-08 31.8 2.4 5.5e-08 31.8 2.4 2.2 2 0 0 2 2 2 1 Retinol binding protein receptor Big_1 PF02369.16 EKX50950.1 - 0.0057 16.6 5.3 32 4.6 0.1 6.9 9 0 0 9 9 9 2 Bacterial Ig-like domain (group 1) MFS_1 PF07690.16 EKX50951.1 - 1.9e-26 92.9 31.4 5.9e-22 78.1 11.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily dCMP_cyt_deam_2 PF08211.12 EKX50952.1 - 3.7e-32 111.3 0.0 6.1e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_1 PF00383.23 EKX50952.1 - 3.5e-14 52.5 0.0 2.1e-12 46.8 0.0 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EKX50952.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 MafB19-like deaminase HSP70 PF00012.20 EKX50953.1 - 5.8e-143 477.2 2.7 1.7e-141 472.3 0.1 2.2 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EKX50953.1 - 6.5e-12 44.9 0.1 1.8e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Prominin PF05478.11 EKX50953.1 - 0.012 13.6 3.4 0.03 12.3 0.6 2.0 2 0 0 2 2 2 0 Prominin CCDC53 PF10152.9 EKX50953.1 - 5.9 7.3 9.0 14 6.1 9.0 1.6 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex TPT PF03151.16 EKX50954.1 - 1.5e-32 113.1 19.9 1.8e-32 112.8 19.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EKX50954.1 - 1e-05 25.7 13.8 1e-05 25.7 13.8 2.1 2 0 0 2 2 2 1 EamA-like transporter family PKD_channel PF08016.12 EKX50955.1 - 5.1e-28 97.9 13.1 5.1e-28 97.9 13.1 1.6 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 EKX50955.1 - 9.3e-13 48.0 22.1 9.3e-13 48.0 22.1 2.0 2 0 0 2 2 2 1 Ion transport protein DUF4570 PF15134.6 EKX50955.1 - 0.24 11.4 2.0 0.57 10.2 2.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) NUDIX PF00293.28 EKX50956.1 - 4.7e-14 52.6 0.0 6.4e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EKX50956.1 - 0.00042 20.3 0.0 0.00055 19.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Peptidase_S8 PF00082.22 EKX50957.1 - 2.9e-40 138.4 1.5 4.5e-20 72.1 0.1 3.0 3 0 0 3 3 3 2 Subtilase family DUF4215 PF13948.6 EKX50957.1 - 2.8e-17 62.8 44.7 1.9e-07 31.4 8.5 4.9 4 0 0 4 4 4 3 Domain of unknown function (DUF4215) PPC PF04151.15 EKX50957.1 - 0.00029 21.9 0.3 0.0025 18.9 0.3 2.8 1 0 0 1 1 1 1 Bacterial pre-peptidase C-terminal domain PA PF02225.22 EKX50957.1 - 0.0015 18.5 0.0 0.0052 16.8 0.0 1.9 1 0 0 1 1 1 1 PA domain hEGF PF12661.7 EKX50957.1 - 0.58 10.9 9.3 0.17 12.6 3.9 3.3 2 0 0 2 2 2 0 Human growth factor-like EGF FHA PF00498.26 EKX50958.1 - 2.3e-20 72.7 0.6 6e-20 71.4 0.6 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EKX50958.1 - 3.5e-10 40.1 0.2 7.9e-10 38.9 0.2 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain SMAP PF15477.6 EKX50958.1 - 4.9e-10 40.2 2.7 4.9e-10 40.2 2.7 1.9 2 0 0 2 2 2 1 Small acidic protein family Pkinase PF00069.25 EKX50959.1 - 9.8e-27 94.0 0.0 1.2e-26 93.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX50959.1 - 4.1e-16 59.1 0.0 4.9e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX50959.1 - 6.5e-10 38.3 0.0 8.5e-10 38.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX50959.1 - 0.0015 18.5 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX50959.1 - 0.086 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sugar_tr PF00083.24 EKX50960.1 - 6.1e-107 358.3 22.2 7.3e-81 272.3 13.4 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EKX50960.1 - 4.9e-29 101.4 28.6 6.8e-26 91.0 16.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily PSI PF01437.25 EKX50960.1 - 0.25 11.9 11.6 0.46 11.1 11.6 1.5 1 0 0 1 1 1 0 Plexin repeat OATP PF03137.20 EKX50960.1 - 1.3 7.3 15.3 0.28 9.4 1.2 3.1 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DHBP_synthase PF00926.19 EKX50961.1 - 2.6e-83 278.3 0.8 3e-83 278.1 0.8 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase HEAT_2 PF13646.6 EKX50962.1 - 1.4e-11 44.7 30.4 8.6e-06 26.1 0.1 7.3 5 2 1 6 6 6 4 HEAT repeats HEAT PF02985.22 EKX50962.1 - 1.1e-08 34.6 16.3 0.93 9.9 0.0 9.6 9 0 0 9 9 9 3 HEAT repeat Cnd1 PF12717.7 EKX50962.1 - 1.9e-05 24.8 4.1 0.00017 21.6 0.2 3.8 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 EKX50962.1 - 0.00086 19.5 3.1 0.15 12.3 0.1 3.4 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_PBS PF03130.16 EKX50962.1 - 0.088 13.5 0.6 2.2 9.2 0.0 3.7 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Adaptin_N PF01602.20 EKX50962.1 - 0.098 11.2 1.6 0.89 8.0 0.5 2.6 2 1 0 2 2 2 0 Adaptin N terminal region FliS PF02561.14 EKX50963.1 - 0.014 15.6 1.3 6 7.2 0.0 3.0 2 1 1 3 3 3 0 Flagellar protein FliS SNF2_N PF00176.23 EKX50965.1 - 5.4e-65 219.4 0.0 5e-64 216.2 0.0 1.9 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX50965.1 - 9.6e-19 67.8 0.1 1.5e-17 64.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX50965.1 - 4e-07 30.2 0.0 3e-06 27.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HEAT PF02985.22 EKX50965.1 - 0.00097 19.2 0.0 0.012 15.8 0.0 2.6 2 0 0 2 2 2 1 HEAT repeat ERCC3_RAD25_C PF16203.5 EKX50965.1 - 0.052 12.8 0.0 0.096 11.9 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Vac14_Fab1_bd PF12755.7 EKX50965.1 - 0.057 14.0 0.0 0.15 12.6 0.0 1.8 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region ACPS PF01648.20 EKX50967.1 - 9.9e-17 61.1 0.3 1.1e-14 54.6 0.1 2.7 2 1 0 2 2 2 2 4'-phosphopantetheinyl transferase superfamily Fe_dep_repress PF01325.19 EKX50967.1 - 0.0014 18.8 0.1 0.43 10.8 0.0 2.4 2 0 0 2 2 2 2 Iron dependent repressor, N-terminal DNA binding domain IQ PF00612.27 EKX50968.1 - 0.0043 16.7 0.3 0.012 15.3 0.3 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif PH PF00169.29 EKX50968.1 - 0.028 14.9 0.1 0.092 13.3 0.1 2.0 1 1 0 1 1 1 0 PH domain Spc7 PF08317.11 EKX50968.1 - 0.23 10.3 9.2 0.46 9.3 9.2 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_23 PF13476.6 EKX50968.1 - 0.29 11.6 7.7 0.66 10.4 7.2 1.9 1 1 0 1 1 1 0 AAA domain P4Ha_N PF08336.11 EKX50968.1 - 0.47 10.5 6.6 1.4 8.9 6.6 1.9 1 1 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Syntaxin_2 PF14523.6 EKX50968.1 - 3.4 8.1 8.6 18 5.7 4.3 3.2 1 1 1 2 2 2 0 Syntaxin-like protein VWA PF00092.28 EKX50969.1 - 2.2e-05 24.8 0.1 0.00017 21.9 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain VGCC_alpha2 PF08473.11 EKX50969.1 - 6e-05 22.0 0.0 0.00014 20.8 0.0 1.6 1 0 0 1 1 1 1 Neuronal voltage-dependent calcium channel alpha 2acd DUF4381 PF14316.6 EKX50969.1 - 0.033 14.4 1.3 0.069 13.4 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) VWA_N PF08399.11 EKX50969.1 - 0.05 14.1 0.1 0.05 14.1 0.1 2.4 3 0 0 3 3 3 0 VWA N-terminal bacHORMA_1 PF18138.1 EKX50969.1 - 0.078 12.9 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 Bacterial HORMA domain family 1 CdvA PF18822.1 EKX50969.1 - 1.2 8.9 7.4 2.6 7.9 7.4 1.5 1 0 0 1 1 1 0 CdvA-like coiled-coil domain Transferase PF02458.15 EKX50970.1 - 5.4e-19 68.2 0.0 8.4e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 Transferase family tRNA-synt_2 PF00152.20 EKX50971.1 - 2.8e-74 250.0 0.1 3.3e-74 249.8 0.1 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 EKX50971.1 - 0.0019 17.7 0.2 0.78 9.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Na_H_Exchanger PF00999.21 EKX50972.1 - 1.5e-18 66.8 39.8 2.5e-18 66.1 39.8 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family EpuA PF11772.8 EKX50972.1 - 8.4 6.2 12.3 41 4.0 12.3 2.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Exo70 PF03081.15 EKX50973.1 - 6e-26 91.4 5.5 6e-26 91.4 5.5 1.8 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Sec34 PF04136.15 EKX50973.1 - 0.033 14.1 2.7 0.19 11.6 0.1 3.1 3 1 0 3 3 3 0 Sec34-like family Sec23_helical PF04815.15 EKX50973.1 - 0.16 11.8 1.1 15 5.4 0.1 2.9 2 0 0 2 2 2 0 Sec23/Sec24 helical domain I_LWEQ PF01608.17 EKX50973.1 - 0.51 10.6 3.4 3.5 7.8 0.0 3.0 3 0 0 3 3 3 0 I/LWEQ domain HMG_box PF00505.19 EKX50974.1 - 1.6e-12 47.6 0.4 1.6e-12 47.6 0.4 3.3 3 1 1 4 4 4 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EKX50974.1 - 3.9e-09 37.0 0.4 3.9e-09 37.0 0.4 3.2 2 1 1 3 3 3 1 HMG-box domain YABBY PF04690.13 EKX50974.1 - 1.8e-05 25.4 0.3 1.8e-05 25.4 0.3 2.2 1 1 0 2 2 2 1 YABBY protein DUF4407 PF14362.6 EKX50974.1 - 0.91 8.8 14.3 1.2 8.5 14.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nucleo_P87 PF07267.11 EKX50974.1 - 1.5 7.6 14.4 1.6 7.5 14.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SOBP PF15279.6 EKX50974.1 - 3.5 8.2 12.9 4.4 7.8 12.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Golgin_A5 PF09787.9 EKX50976.1 - 0.00089 18.8 15.3 0.0017 17.9 15.3 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 5 Filament PF00038.21 EKX50976.1 - 0.0012 18.5 12.1 0.0019 17.8 12.1 1.2 1 0 0 1 1 1 1 Intermediate filament protein AAA_25 PF13481.6 EKX50976.1 - 0.0023 17.6 0.0 0.0075 15.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain TPR_MLP1_2 PF07926.12 EKX50976.1 - 0.0056 16.7 17.0 0.0092 16.0 17.0 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein AAA_11 PF13086.6 EKX50976.1 - 0.0063 16.3 16.7 0.41 10.4 0.0 2.8 2 1 1 3 3 3 1 AAA domain SKA1 PF07160.12 EKX50976.1 - 0.0091 15.9 8.7 0.014 15.2 8.7 1.2 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 AAA_22 PF13401.6 EKX50976.1 - 0.013 15.7 0.0 0.04 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EKX50976.1 - 0.015 15.7 0.0 0.036 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DUF4407 PF14362.6 EKX50976.1 - 0.016 14.6 7.6 0.024 14.0 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 EKX50976.1 - 0.016 14.9 4.0 0.016 14.9 4.0 2.4 1 1 1 2 2 2 0 Septum formation initiator AAA_7 PF12775.7 EKX50976.1 - 0.016 14.7 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region zf-C4H2 PF10146.9 EKX50976.1 - 0.018 15.4 7.0 0.038 14.3 7.0 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein ADIP PF11559.8 EKX50976.1 - 0.02 15.0 15.2 0.036 14.2 15.2 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 EKX50976.1 - 0.021 15.3 24.2 0.026 15.1 20.2 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Lebercilin PF15619.6 EKX50976.1 - 0.029 14.0 24.6 0.14 11.8 24.6 1.9 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.6 EKX50976.1 - 0.035 13.5 21.7 0.068 12.5 21.7 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding HAUS5 PF14817.6 EKX50976.1 - 0.043 12.6 11.0 0.066 12.0 11.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 EzrA PF06160.12 EKX50976.1 - 0.049 11.8 15.4 0.078 11.1 15.4 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA V_ATPase_I PF01496.19 EKX50976.1 - 0.06 11.3 4.7 0.084 10.8 4.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.20 EKX50976.1 - 0.11 12.5 23.1 0.03 14.3 3.0 2.5 2 0 0 2 2 2 0 Prefoldin subunit FlxA PF14282.6 EKX50976.1 - 0.15 12.1 20.9 0.19 11.7 0.4 2.3 1 1 1 2 2 2 0 FlxA-like protein AAA_24 PF13479.6 EKX50976.1 - 0.2 11.4 0.0 0.2 11.4 0.0 1.7 2 0 0 2 2 1 0 AAA domain Exonuc_VII_L PF02601.15 EKX50976.1 - 0.29 10.6 6.7 0.53 9.8 6.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4200 PF13863.6 EKX50976.1 - 0.37 11.2 26.3 2.2 8.7 13.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) T3SSipB PF16535.5 EKX50976.1 - 0.57 10.7 8.2 1.1 9.8 8.2 1.4 1 0 0 1 1 1 0 Type III cell invasion protein SipB TMF_DNA_bd PF12329.8 EKX50976.1 - 0.83 9.7 26.8 1.9 8.5 6.2 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Prefoldin PF02996.17 EKX50976.1 - 0.85 9.6 12.3 0.12 12.2 1.8 2.3 2 0 0 2 2 2 0 Prefoldin subunit IFT57 PF10498.9 EKX50976.1 - 0.88 8.5 15.1 1.3 7.9 15.1 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CENP-H PF05837.12 EKX50976.1 - 1.1 9.7 13.3 3 8.3 13.3 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) COG2 PF06148.11 EKX50976.1 - 1.3 9.1 14.8 18 5.4 0.0 3.2 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TMPIT PF07851.13 EKX50976.1 - 1.3 8.2 14.0 2.1 7.5 14.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein ABC_tran PF00005.27 EKX50976.1 - 1.6 9.2 4.3 52 4.3 0.0 2.6 2 0 0 2 2 2 0 ABC transporter DUF2031 PF09592.10 EKX50976.1 - 1.9 8.0 13.2 3.2 7.2 13.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) Spc7 PF08317.11 EKX50976.1 - 2 7.2 23.0 2.8 6.8 4.5 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein FAM76 PF16046.5 EKX50976.1 - 2.2 7.6 13.1 3.4 6.9 13.1 1.2 1 0 0 1 1 1 0 FAM76 protein CCDC-167 PF15188.6 EKX50976.1 - 2.4 8.5 19.0 9.6 6.6 18.9 2.1 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF3552 PF12072.8 EKX50976.1 - 3.4 7.0 25.2 7.3 6.0 25.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) LMBR1 PF04791.16 EKX50976.1 - 7.4 5.4 7.2 11 4.8 7.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-C2HC_2 PF13913.6 EKX50977.1 - 5.4 7.0 12.4 10 6.1 0.5 4.3 3 1 0 3 3 3 0 zinc-finger of a C2HC-type AAA_25 PF13481.6 EKX50978.1 - 0.0045 16.6 0.1 0.01 15.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EKX50978.1 - 0.0063 16.9 0.0 0.015 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EKX50978.1 - 0.022 15.1 0.0 0.056 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EKX50981.1 - 3.4e-05 23.8 6.6 0.33 10.7 6.7 2.4 2 0 0 2 2 2 2 AAA domain TPR_MLP1_2 PF07926.12 EKX50981.1 - 0.0016 18.5 14.3 0.0026 17.8 14.3 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 EKX50981.1 - 0.0017 18.9 18.7 0.004 17.7 18.4 1.7 1 1 0 1 1 1 1 Apg6 coiled-coil region AAA_25 PF13481.6 EKX50981.1 - 0.0022 17.6 0.0 0.0074 15.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain Filament PF00038.21 EKX50981.1 - 0.003 17.2 10.0 0.0047 16.5 10.0 1.2 1 0 0 1 1 1 1 Intermediate filament protein EzrA PF06160.12 EKX50981.1 - 0.01 14.1 11.4 0.016 13.4 11.4 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA AAA_22 PF13401.6 EKX50981.1 - 0.014 15.7 0.0 0.04 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EKX50981.1 - 0.015 15.7 0.0 0.035 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 EKX50981.1 - 0.015 14.8 0.0 0.038 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region DivIC PF04977.15 EKX50981.1 - 0.017 14.9 4.1 0.017 14.9 4.1 2.4 1 1 1 2 2 2 0 Septum formation initiator ADIP PF11559.8 EKX50981.1 - 0.02 15.0 11.0 0.041 14.0 11.0 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding SKA1 PF07160.12 EKX50981.1 - 0.021 14.7 7.9 0.033 14.1 7.9 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 FH2 PF02181.23 EKX50981.1 - 0.026 13.7 5.8 0.039 13.1 5.8 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain Golgin_A5 PF09787.9 EKX50981.1 - 0.038 13.4 13.4 0.073 12.5 13.4 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF4407 PF14362.6 EKX50981.1 - 0.049 13.0 4.5 0.072 12.4 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lebercilin PF15619.6 EKX50981.1 - 0.074 12.7 21.5 0.44 10.2 21.5 1.9 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease FlxA PF14282.6 EKX50981.1 - 0.08 12.9 17.9 0.19 11.7 0.4 2.2 1 1 1 2 2 2 0 FlxA-like protein AAA_24 PF13479.6 EKX50981.1 - 0.08 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain FapA PF03961.13 EKX50981.1 - 0.11 11.1 10.2 0.17 10.5 10.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4200 PF13863.6 EKX50981.1 - 0.12 12.8 23.8 0.66 10.4 11.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) zf-C4H2 PF10146.9 EKX50981.1 - 0.13 12.6 7.2 0.27 11.5 7.2 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein DUF3552 PF12072.8 EKX50981.1 - 0.15 11.5 21.6 0.31 10.4 21.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) V_ATPase_I PF01496.19 EKX50981.1 - 0.18 9.7 5.7 0.25 9.2 5.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GLE1 PF07817.13 EKX50981.1 - 0.25 10.5 1.2 0.49 9.6 1.2 1.4 1 0 0 1 1 1 0 GLE1-like protein Tropomyosin_1 PF12718.7 EKX50981.1 - 0.25 11.5 18.2 0.46 10.6 18.2 1.3 1 0 0 1 1 1 0 Tropomyosin like ABC_tran_CTD PF16326.5 EKX50981.1 - 0.28 11.5 12.5 1.5 9.1 12.5 2.3 1 1 0 1 1 1 0 ABC transporter C-terminal domain Exonuc_VII_L PF02601.15 EKX50981.1 - 0.31 10.6 4.5 0.57 9.7 4.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit T3SSipB PF16535.5 EKX50981.1 - 0.34 11.4 6.0 0.67 10.4 6.0 1.4 1 0 0 1 1 1 0 Type III cell invasion protein SipB COG2 PF06148.11 EKX50981.1 - 0.35 11.0 12.2 19 5.4 0.0 3.1 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 GAS PF13851.6 EKX50981.1 - 0.37 10.1 19.1 0.68 9.3 19.1 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding HAUS5 PF14817.6 EKX50981.1 - 0.48 9.1 11.8 0.75 8.5 11.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 IFT57 PF10498.9 EKX50981.1 - 0.54 9.2 12.8 0.81 8.6 12.8 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 TMPIT PF07851.13 EKX50981.1 - 0.71 9.1 11.5 1.2 8.4 11.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein OmpH PF03938.14 EKX50981.1 - 1.1 9.6 17.0 2.3 8.5 17.0 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Prefoldin PF02996.17 EKX50981.1 - 1.5 8.8 12.1 0.12 12.3 1.8 2.3 2 0 0 2 2 2 0 Prefoldin subunit FAM76 PF16046.5 EKX50981.1 - 1.7 7.9 10.8 2.7 7.3 10.8 1.2 1 0 0 1 1 1 0 FAM76 protein CCDC-167 PF15188.6 EKX50981.1 - 2.2 8.7 19.0 8 6.9 18.9 2.1 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Spc7 PF08317.11 EKX50981.1 - 2.4 7.0 19.6 6.2 5.6 19.6 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF2031 PF09592.10 EKX50981.1 - 2.7 7.4 10.6 4.6 6.7 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) CENP-H PF05837.12 EKX50981.1 - 2.8 8.4 11.1 6.8 7.1 11.1 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) PCRF PF03462.18 EKX50981.1 - 3.1 7.6 10.4 7.1 6.4 10.4 1.6 1 0 0 1 1 1 0 PCRF domain Snf7 PF03357.21 EKX50981.1 - 5.1 6.7 19.5 0.56 9.8 3.0 2.4 1 1 1 2 2 2 0 Snf7 LMBR1 PF04791.16 EKX50981.1 - 5.1 5.9 5.4 7.4 5.3 5.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF812 PF05667.11 EKX50981.1 - 6.2 5.6 23.4 83 1.9 23.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Prefoldin_2 PF01920.20 EKX50981.1 - 7.5 6.6 27.4 0.78 9.7 7.4 2.5 1 1 1 2 2 2 0 Prefoldin subunit UPF0242 PF06785.11 EKX50981.1 - 8.2 6.5 14.3 17 5.5 14.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 EKX50981.1 - 8.4 5.4 14.3 14 4.7 14.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 EKX50981.1 - 9.4 6.4 18.0 1.1e+02 2.9 18.0 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) WD40 PF00400.32 EKX50984.1 - 3.3e-102 331.5 59.9 2.3e-09 37.7 0.5 12.1 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX50984.1 - 2.7e-51 171.8 16.4 5.9e-05 23.3 0.0 11.5 1 1 11 12 12 12 11 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EKX50984.1 - 5.6e-21 74.8 16.2 0.32 9.6 0.0 11.0 5 2 5 11 11 11 11 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EKX50984.1 - 3.7e-18 65.6 8.7 0.61 9.0 0.0 10.6 1 1 10 11 11 11 7 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 EKX50984.1 - 1.2e-06 28.5 50.5 0.11 12.2 2.8 8.3 1 1 5 7 7 7 5 Lipoprotein LpqB beta-propeller domain Hira PF07569.11 EKX50984.1 - 0.00053 19.8 9.6 36 4.0 0.0 8.7 9 2 3 12 12 12 0 TUP1-like enhancer of split PQQ_3 PF13570.6 EKX50984.1 - 0.00083 19.8 27.9 33 5.1 0.0 10.4 9 2 1 10 10 10 0 PQQ-like domain WYL_2 PF10902.8 EKX50984.1 - 0.0027 18.0 4.9 40 4.7 0.0 7.9 7 3 4 11 11 11 0 WYL_2, Sm-like SH3 beta-barrel fold Kelch_6 PF13964.6 EKX50984.1 - 0.008 16.4 22.5 46 4.5 0.0 10.0 11 0 0 11 11 11 0 Kelch motif PQQ PF01011.21 EKX50984.1 - 0.074 13.0 8.0 1.5e+02 2.5 0.0 7.2 11 0 0 11 11 11 0 PQQ enzyme repeat CDPS PF16715.5 EKX50984.1 - 3.9 7.1 5.8 11 5.6 0.0 4.3 5 0 0 5 5 5 0 Cyclodipeptide synthase Pkinase_Tyr PF07714.17 EKX50985.1 - 6.8e-42 143.5 0.0 2.3e-41 141.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX50985.1 - 3.7e-14 52.7 0.0 2e-13 50.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain U-box PF04564.15 EKX50985.1 - 0.029 14.6 0.0 0.047 13.9 0.0 1.3 1 0 0 1 1 1 0 U-box domain AAA_25 PF13481.6 EKX50986.1 - 0.0041 16.7 0.1 0.009 15.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EKX50986.1 - 0.022 15.1 0.0 0.056 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EKX50986.1 - 0.044 14.2 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain CBFD_NFYB_HMF PF00808.23 EKX50988.1 - 0.0061 16.8 0.9 0.047 14.0 0.1 2.6 3 1 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DASH_Dad4 PF08650.10 EKX50988.1 - 0.054 13.5 2.3 0.17 11.8 0.3 2.7 3 0 0 3 3 3 0 DASH complex subunit Dad4 PDZ_2 PF13180.6 EKX50991.1 - 0.011 16.0 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 EKX50991.1 - 0.013 15.4 0.0 0.033 14.0 0.0 1.8 1 0 0 1 1 1 0 PDZ domain Tricorn_PDZ PF14685.6 EKX50991.1 - 0.032 14.2 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 Tricorn protease PDZ domain CLZ PF16526.5 EKX50991.1 - 0.11 12.9 0.1 0.23 11.9 0.1 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HR1 PF02185.16 EKX50991.1 - 0.32 11.2 1.4 0.47 10.6 0.4 1.9 2 0 0 2 2 2 0 Hr1 repeat Ank_2 PF12796.7 EKX50992.1 - 5.3e-08 33.3 0.0 3.1e-07 30.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX50992.1 - 2.6e-05 24.3 0.0 0.6 10.9 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EKX50992.1 - 5.7e-05 23.3 0.4 0.14 12.5 0.2 4.0 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX50992.1 - 0.00013 22.4 0.0 0.014 16.0 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Peptidase_M10 PF00413.24 EKX50992.1 - 0.00021 21.2 0.1 0.00048 20.0 0.0 1.4 1 1 0 1 1 1 1 Matrixin Ank PF00023.30 EKX50992.1 - 0.00049 20.4 0.1 19 5.9 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Reprolysin_5 PF13688.6 EKX50992.1 - 0.016 15.4 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Metallopep PF12044.8 EKX50992.1 - 0.15 10.6 1.7 0.26 9.8 1.7 1.2 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_3 PF13582.6 EKX50992.1 - 0.19 12.3 0.0 0.47 11.0 0.0 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like PKD_channel PF08016.12 EKX50993.1 - 2.8e-15 55.9 21.1 7.2e-15 54.6 19.5 2.4 2 1 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 EKX50993.1 - 2.2e-12 46.7 24.2 2.2e-12 46.7 24.2 1.6 2 0 0 2 2 2 1 Ion transport protein SHOCT PF09851.9 EKX50994.1 - 0.0016 18.1 0.2 0.0016 18.1 0.2 3.9 5 0 0 5 5 5 1 Short C-terminal domain DUF1949 PF09186.11 EKX50994.1 - 0.055 13.4 0.6 0.46 10.4 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) LRR_8 PF13855.6 EKX50997.1 - 7.2e-34 115.3 17.1 1.7e-13 50.1 2.2 3.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EKX50997.1 - 7.4e-19 67.6 18.2 8.7e-06 26.0 4.3 4.1 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX50997.1 - 6.1e-12 45.6 0.0 5e-07 29.7 0.0 1.7 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 EKX50997.1 - 3e-07 30.1 1.6 0.0032 17.0 0.7 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 EKX50997.1 - 2.5e-05 24.2 14.0 10 7.1 0.2 6.4 6 1 0 6 6 6 2 Leucine Rich Repeat YcgL PF05166.13 EKX50997.1 - 0.0057 17.0 0.1 0.092 13.1 0.0 2.7 2 1 1 3 3 3 1 YcgL domain LRR_6 PF13516.6 EKX50997.1 - 0.74 10.0 15.4 42 4.6 0.0 5.9 6 0 0 6 6 6 0 Leucine Rich repeat CSTF_C PF14304.6 EKX50997.1 - 1.3 8.7 4.9 44 3.8 0.2 3.3 3 0 0 3 3 3 0 Transcription termination and cleavage factor C-terminal S-methyl_trans PF02574.16 EKX50998.1 - 2.8e-66 224.1 0.0 3.2e-66 223.9 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase VP40 PF07447.12 EKX50998.1 - 0.04 13.0 0.0 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 Matrix protein VP40 RabGAP-TBC PF00566.18 EKX50999.1 - 5.7e-13 49.0 9.3 8.5e-12 45.2 1.6 2.5 3 0 0 3 3 3 2 Rab-GTPase-TBC domain LRR_8 PF13855.6 EKX51000.1 - 1.8e-128 418.4 113.0 5.6e-17 61.3 2.7 8.0 1 1 10 11 11 11 11 Leucine rich repeat LRR_4 PF12799.7 EKX51000.1 - 1.3e-45 152.6 48.7 2.1e-07 31.1 1.0 8.0 3 2 5 9 9 9 9 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX51000.1 - 2.3e-39 134.3 0.0 1.5e-12 47.6 0.1 3.4 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EKX51000.1 - 3.8e-23 78.5 30.0 0.96 10.3 0.1 13.0 13 0 0 13 13 13 8 Leucine Rich Repeat LRR_9 PF14580.6 EKX51000.1 - 3.2e-14 52.8 0.1 0.0026 17.3 0.0 4.1 1 1 4 5 5 5 5 Leucine-rich repeat LRR_6 PF13516.6 EKX51000.1 - 8.9e-07 28.5 58.2 1.6 9.0 0.7 12.9 13 0 0 13 13 13 7 Leucine Rich repeat GIT_SHD PF08518.11 EKX51000.1 - 9.9e-05 21.9 1.1 1.6e+02 2.0 0.0 8.8 14 0 0 14 14 14 0 Spa2 homology domain (SHD) of GIT ATP-synt_E PF05680.12 EKX51000.1 - 0.059 13.7 0.3 72 3.8 0.0 4.3 1 1 3 4 4 4 0 ATP synthase E chain DUF4516 PF14990.6 EKX51000.1 - 0.074 12.8 0.2 1.6e+02 2.1 0.0 4.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4516) Importin_rep_6 PF18829.1 EKX51000.1 - 0.16 12.1 0.2 2.2e+02 2.0 0.0 4.1 6 0 0 6 6 6 0 Importin repeat 6 MerE PF05052.12 EKX51000.1 - 0.24 11.4 7.4 35 4.4 0.0 4.7 3 1 2 5 5 5 0 MerE protein LRRNT PF01462.18 EKX51000.1 - 0.65 9.7 4.8 4e+02 0.8 0.0 6.5 8 0 0 8 8 8 0 Leucine rich repeat N-terminal domain CSTF_C PF14304.6 EKX51000.1 - 1.1 8.8 12.3 97 2.7 0.0 7.4 11 0 0 11 11 11 0 Transcription termination and cleavage factor C-terminal Forkhead_N PF08430.12 EKX51000.1 - 1.7 9.2 15.9 70 4.0 5.2 4.1 1 1 1 2 2 2 0 Forkhead N-terminal region DUF1097 PF06496.11 EKX51000.1 - 7.4 6.7 14.6 0.24 11.5 4.4 3.1 2 2 1 3 3 3 0 Protein of unknown function (DUF1097) Cyclin_N PF00134.23 EKX51001.1 - 9.1e-46 154.7 0.7 9.1e-46 154.7 0.7 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EKX51001.1 - 2e-13 50.4 0.4 4.3e-13 49.4 0.4 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain MATH PF00917.26 EKX51002.1 - 5e-12 46.0 0.0 1.2e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 MATH domain DUF5401 PF17380.2 EKX51002.1 - 0.0022 16.2 38.4 0.0031 15.7 38.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5401) Borrelia_P83 PF05262.11 EKX51002.1 - 0.024 13.2 35.7 0.034 12.7 35.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Zip PF02535.22 EKX51002.1 - 0.24 10.6 7.9 0.52 9.5 7.9 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter GPCR_chapero_1 PF11904.8 EKX51002.1 - 2.4 7.5 18.5 11 5.3 18.4 1.9 1 1 0 1 1 1 0 GPCR-chaperone Sin_N PF04801.13 EKX51002.1 - 2.4 7.3 28.1 4.1 6.5 28.1 1.3 1 0 0 1 1 1 0 Sin-like protein conserved region Ycf1 PF05758.12 EKX51002.1 - 6.2 4.6 10.5 10 3.8 10.5 1.3 1 0 0 1 1 1 0 Ycf1 Ion_trans_2 PF07885.16 EKX51003.1 - 1.4e-13 50.6 6.4 1.4e-13 50.6 6.4 2.2 2 0 0 2 2 2 1 Ion channel BK_channel_a PF03493.18 EKX51003.1 - 2.8e-11 43.5 0.0 6e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Prefoldin_2 PF01920.20 EKX51004.1 - 2.9e-16 59.4 11.1 4.1e-16 58.9 11.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit PEARLI-4 PF05278.12 EKX51004.1 - 0.026 14.1 4.0 0.026 14.1 4.0 1.7 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Tektin PF03148.14 EKX51004.1 - 0.03 13.1 13.0 0.019 13.8 4.6 2.0 2 0 0 2 2 2 0 Tektin family Seryl_tRNA_N PF02403.22 EKX51004.1 - 0.11 12.7 8.2 0.078 13.2 1.6 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 EKX51004.1 - 1.3 8.3 7.5 0.83 9.0 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4298 PF14131.6 EKX51004.1 - 1.8 8.6 9.3 6.6 6.8 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) Atg14 PF10186.9 EKX51004.1 - 3.9 6.5 12.2 7.9 5.5 12.2 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Tup_N PF08581.10 EKX51004.1 - 5.5 7.4 16.0 0.78 10.1 5.5 2.2 2 0 0 2 2 2 0 Tup N-terminal Spc24 PF08286.11 EKX51004.1 - 8.3 6.7 14.0 4.7 7.5 4.3 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Dus PF01207.17 EKX51006.1 - 3.6e-69 233.2 0.0 4.4e-69 232.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) NMO PF03060.15 EKX51006.1 - 1.3e-05 24.7 0.0 1.6e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 EKX51006.1 - 0.00045 19.8 0.0 0.001 18.6 0.0 1.5 1 1 0 1 1 1 1 Histidine biosynthesis protein G3P_antiterm PF04309.12 EKX51006.1 - 0.0017 17.8 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 Glycerol-3-phosphate responsive antiterminator ThiG PF05690.14 EKX51006.1 - 0.008 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 EKX51006.1 - 0.022 14.0 0.0 5.6 6.1 0.0 2.1 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase TMP-TENI PF02581.17 EKX51006.1 - 0.18 11.2 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase FMN_dh PF01070.18 EKX51006.1 - 0.19 10.7 0.0 0.25 10.3 0.0 1.1 1 0 0 1 1 1 0 FMN-dependent dehydrogenase IMPDH PF00478.25 EKX51006.1 - 0.22 10.5 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Pkinase PF00069.25 EKX51008.1 - 1.1e-67 228.2 0.0 1.2e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX51008.1 - 5.7e-32 111.0 0.0 7e-32 110.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX51008.1 - 7e-07 28.8 0.0 2.8e-06 26.8 0.0 2.0 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EKX51008.1 - 0.0056 16.1 0.0 0.0078 15.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EKX51008.1 - 0.03 14.0 0.1 0.91 9.1 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Homeodomain PF00046.29 EKX51009.1 - 9.6e-12 44.6 8.0 0.029 14.2 0.0 4.5 4 0 0 4 4 4 4 Homeodomain DUF3220 PF11516.8 EKX51009.1 - 0.00028 21.1 1.4 3.3 8.0 0.1 4.2 3 1 1 4 4 4 2 Protein of unknown function (DUF3120) DUF4588 PF15251.6 EKX51009.1 - 0.0068 16.2 3.2 0.18 11.5 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4588) Flu_M1 PF00598.19 EKX51009.1 - 0.15 11.5 0.4 20 4.7 0.0 3.0 3 0 0 3 3 3 0 Influenza Matrix protein (M1) HMG_box PF00505.19 EKX51010.1 - 1.4e-08 35.0 1.7 3.9e-08 33.6 1.7 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box Mif2_N PF15624.6 EKX51010.1 - 0.00057 20.6 4.8 0.00057 20.6 4.8 4.5 2 1 2 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Ccdc124 PF06244.12 EKX51010.1 - 0.0047 17.5 8.6 0.0047 17.5 8.6 3.4 3 1 0 3 3 3 1 Coiled-coil domain-containing protein 124 /Oxs1 Pkinase PF00069.25 EKX51012.1 - 7.6e-34 117.3 0.0 9.2e-34 117.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX51012.1 - 6e-12 45.4 0.0 7.5e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX51012.1 - 0.066 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pox_ser-thr_kin PF05445.11 EKX51012.1 - 0.14 11.1 0.0 0.23 10.4 0.0 1.3 1 1 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 EKX51012.1 - 0.16 10.7 0.0 0.28 9.9 0.0 1.3 2 0 0 2 2 2 0 Fungal protein kinase DUF515 PF04415.12 EKX51014.1 - 3.5 5.9 5.8 4.6 5.5 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Fungal_TACC PF12709.7 EKX51015.1 - 0.052 14.0 5.2 0.052 14.0 5.2 4.3 1 1 3 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins Chordopox_RPO7 PF05864.12 EKX51015.1 - 0.075 13.3 3.1 12 6.2 0.1 3.4 3 0 0 3 3 3 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Occludin_ELL PF07303.13 EKX51015.1 - 0.84 10.4 15.4 0.53 11.0 2.4 2.7 1 1 0 2 2 2 0 Occludin homology domain TPR_MLP1_2 PF07926.12 EKX51015.1 - 1.7 8.7 32.5 13 5.9 16.8 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Metallophos PF00149.28 EKX51016.1 - 3.8e-16 60.2 0.1 7.9e-16 59.2 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase fn3_PAP PF17808.1 EKX51016.1 - 2.1e-06 27.8 0.0 3.1e-05 24.0 0.0 2.5 2 0 0 2 2 2 1 Fn3-like domain from Purple Acid Phosphatase Metallophos_C PF14008.6 EKX51016.1 - 1.8e-05 25.5 0.0 5.6e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 EKX51016.1 - 5.6e-05 23.6 0.0 0.00016 22.1 0.0 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain DAGK_cat PF00781.24 EKX51017.1 - 2.5e-20 72.4 0.0 3.8e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 EKX51017.1 - 0.023 13.9 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 ATP-NAD kinase GP11 PF08677.10 EKX51017.1 - 0.04 13.4 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 GP11 baseplate wedge protein SDA1 PF05285.12 EKX51020.1 - 0.4 10.1 43.8 0.52 9.7 43.8 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EKX51020.1 - 0.66 8.1 47.7 0.66 8.1 47.7 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EKX51020.1 - 1 7.4 50.6 1.3 7.0 50.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi Drc1-Sld2 PF11719.8 EKX51020.1 - 7.7 5.9 27.0 9 5.7 27.0 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein NPR3 PF03666.13 EKX51020.1 - 8.1 5.1 19.9 9.6 4.9 19.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SpoIIIAH PF12685.7 EKX51020.1 - 9.1 6.1 17.6 11 5.7 17.6 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Ribul_P_3_epim PF00834.19 EKX51021.1 - 1.5e-87 292.1 0.3 1.8e-87 291.9 0.3 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 EKX51021.1 - 2.8e-07 30.5 0.0 0.00011 22.1 0.0 2.2 2 0 0 2 2 2 2 Quinolinate phosphoribosyl transferase, C-terminal domain DUF934 PF06073.12 EKX51021.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF934) His_biosynth PF00977.21 EKX51021.1 - 0.026 14.0 0.0 0.04 13.4 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein TMP-TENI PF02581.17 EKX51021.1 - 0.047 13.0 0.1 0.26 10.6 0.0 2.0 2 0 0 2 2 2 0 Thiamine monophosphate synthase Cons_hypoth95 PF03602.15 EKX51022.1 - 2.1e-36 125.3 0.0 2.6e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 EKX51022.1 - 0.096 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MHCassoc_trimer PF08831.10 EKX51023.1 - 0.13 12.3 1.9 0.2 11.7 1.9 1.3 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain Ras PF00071.22 EKX51028.1 - 2.1e-54 183.5 0.0 2.5e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EKX51028.1 - 3.3e-34 117.7 0.0 6.2e-34 116.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EKX51028.1 - 3e-14 52.9 0.0 3.5e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EKX51028.1 - 3.9e-08 32.9 0.0 5.2e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EKX51028.1 - 1.3e-06 28.1 0.2 4.8e-05 23.0 0.1 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EKX51028.1 - 2.1e-06 27.8 0.2 0.024 14.5 0.0 2.7 1 1 1 3 3 3 2 RsgA GTPase SRPRB PF09439.10 EKX51028.1 - 2.4e-05 23.9 0.0 4e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EKX51028.1 - 0.0003 20.9 0.0 0.00053 20.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EKX51028.1 - 0.0029 17.1 0.1 0.051 13.1 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 EKX51028.1 - 0.006 16.4 0.0 0.31 10.8 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 EKX51028.1 - 0.017 15.0 0.4 0.045 13.7 0.3 1.7 1 1 1 2 2 2 0 NTPase PduV-EutP PF10662.9 EKX51028.1 - 0.031 14.0 0.3 0.62 9.8 0.3 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 EKX51028.1 - 0.042 13.8 0.1 0.077 12.9 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 EKX51028.1 - 0.046 14.0 0.4 0.33 11.2 0.1 2.3 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 EKX51028.1 - 0.067 12.8 0.1 5.7 6.5 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 EKX51028.1 - 0.097 13.1 0.1 0.18 12.2 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 EKX51028.1 - 0.13 11.8 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 EKX51028.1 - 0.13 11.6 0.0 0.36 10.2 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein Myosin_head PF00063.21 EKX51029.1 - 1.9e-216 720.4 0.9 2.7e-216 719.9 0.9 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 EKX51029.1 - 0.00018 21.0 5.0 0.23 11.4 0.9 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif RsgA_GTPase PF03193.16 EKX51029.1 - 0.01 15.7 0.0 0.03 14.2 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 EKX51029.1 - 0.016 15.5 0.5 0.13 12.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EKX51029.1 - 0.15 12.5 0.0 0.15 12.5 0.0 3.8 3 1 1 4 4 4 0 AAA ATPase domain MS_channel PF00924.18 EKX51029.1 - 0.7 9.4 9.3 3.5 7.1 9.3 2.2 1 0 0 1 1 1 0 Mechanosensitive ion channel Wzy_C PF04932.15 EKX51029.1 - 1.5 8.4 7.2 3.6 7.2 7.2 1.6 1 0 0 1 1 1 0 O-Antigen ligase Bcr-Abl_Oligo PF09036.10 EKX51029.1 - 3.9 7.6 7.9 0.62 10.1 2.0 2.8 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Palm_thioest PF02089.15 EKX51030.1 - 6.2e-82 275.1 0.0 7.7e-82 274.8 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 EKX51030.1 - 0.031 13.8 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 EKX51030.1 - 0.1 12.2 0.1 0.15 11.7 0.1 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold LRR_4 PF12799.7 EKX51035.1 - 1.3e-20 73.2 17.3 5.3e-06 26.7 0.1 4.2 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX51035.1 - 3.6e-19 68.3 24.2 6.4e-07 29.0 1.1 3.8 2 1 2 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 EKX51035.1 - 6.4e-05 22.5 6.5 0.0012 18.4 1.9 2.3 2 1 1 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 EKX51035.1 - 0.00015 21.8 11.9 11 7.0 0.1 6.7 5 1 1 6 6 6 1 Leucine Rich Repeat Sgf11_N PF18519.1 EKX51035.1 - 0.57 9.8 3.5 9.3 5.9 0.2 2.5 2 0 0 2 2 2 0 SAGA-associated factor 11 N-terminal domain UBM PF14377.6 EKX51035.1 - 0.62 9.6 2.2 39 3.9 0.0 3.3 3 0 0 3 3 3 0 Ubiquitin binding region RRM_1 PF00076.22 EKX51036.1 - 2.6e-53 177.7 0.3 1.8e-20 72.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EKX51036.1 - 4.4e-08 32.9 1.5 0.3 11.0 0.0 4.5 5 0 0 5 5 5 3 Occluded RNA-recognition motif RRM_7 PF16367.5 EKX51036.1 - 2.9e-07 30.5 0.2 0.016 15.3 0.2 3.0 2 1 0 2 2 2 2 RNA recognition motif HSP70 PF00012.20 EKX51038.1 - 7.7e-262 869.8 4.9 8.7e-262 869.6 4.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EKX51038.1 - 9.4e-16 57.5 0.0 7.9e-15 54.5 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EKX51038.1 - 0.15 11.7 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain TPR_1 PF00515.28 EKX51039.1 - 1.8e-12 46.5 0.0 4.1e-05 23.2 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX51039.1 - 9.1e-11 41.0 0.6 0.00096 19.1 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX51039.1 - 4.3e-06 26.9 2.8 0.15 12.4 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX51039.1 - 7.8e-06 25.5 7.5 0.013 15.2 0.0 3.3 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.6 EKX51039.1 - 0.00036 20.5 0.0 1.8 9.0 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 EKX51039.1 - 0.00056 19.9 0.1 2.1 8.5 0.0 2.6 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 EKX51039.1 - 0.00092 19.1 2.8 3.4 7.9 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX51039.1 - 0.00093 19.3 1.5 0.15 12.2 0.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX51039.1 - 0.0099 16.5 10.9 0.014 16.1 0.1 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 EKX51039.1 - 0.012 15.1 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 SHNi-TPR BTAD PF03704.17 EKX51039.1 - 0.027 14.9 4.5 14 6.1 0.1 3.2 2 1 1 3 3 3 0 Bacterial transcriptional activator domain DUF3856 PF12968.7 EKX51039.1 - 0.033 14.3 0.2 2.9 8.0 0.1 2.7 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_19 PF14559.6 EKX51039.1 - 0.048 14.2 4.6 0.23 12.0 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX51039.1 - 0.054 13.4 6.3 0.65 9.9 0.1 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX51039.1 - 0.056 14.1 0.8 2 9.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EKX51039.1 - 0.79 10.5 13.9 1.2 9.9 0.5 4.6 5 1 1 6 6 5 0 Tetratricopeptide repeat DENN PF02141.21 EKX51040.1 - 2.8e-25 89.3 4.3 2.8e-25 89.3 4.3 2.7 3 0 0 3 3 3 1 DENN (AEX-3) domain SH3_1 PF00018.28 EKX51040.1 - 3.1e-07 29.9 0.0 6.4e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EKX51040.1 - 1.1e-06 28.3 0.0 2.3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EKX51040.1 - 3.5e-06 26.8 0.1 1.1e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain RhoGAP PF00620.27 EKX51040.1 - 4.7e-06 26.5 0.5 1.1e-05 25.2 0.5 1.7 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 EKX51040.1 - 0.00068 20.1 0.0 0.0017 18.9 0.0 1.8 1 0 0 1 1 1 1 PH domain EF-hand_7 PF13499.6 EKX51041.1 - 1.8e-12 47.5 3.2 9e-10 38.9 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX51041.1 - 7.4e-12 44.2 0.8 0.00017 21.2 0.1 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 EKX51041.1 - 8.4e-11 41.6 1.6 8.2e-10 38.4 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX51041.1 - 2.2e-10 39.3 8.7 6.8e-05 22.1 0.1 4.0 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 EKX51041.1 - 3.6e-06 26.2 0.4 2.1e-05 23.8 0.0 2.5 2 0 0 2 2 2 1 EF hand p25-alpha PF05517.12 EKX51041.1 - 0.0096 16.1 0.0 1.4 9.1 0.0 2.2 2 0 0 2 2 2 2 p25-alpha EF-hand_4 PF12763.7 EKX51041.1 - 0.51 10.3 2.4 2.1 8.4 0.1 2.3 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand RNA_pol_Rpb1_R PF05001.13 EKX51042.1 - 5 7.7 9.3 0.29 11.6 3.8 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb1 C-terminal repeat PH PF00169.29 EKX51044.1 - 3.8e-05 24.1 0.1 8e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 PH domain Spermine_synth PF01564.17 EKX51045.1 - 3.7e-29 101.5 0.0 4.8e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EKX51045.1 - 1.3e-07 31.3 0.1 2.2e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 EKX51045.1 - 0.0014 19.3 0.0 0.0027 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF2286 PF10051.9 EKX51045.1 - 0.1 12.4 0.1 6.8 6.5 0.0 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2286) Methyltransf_11 PF08241.12 EKX51045.1 - 0.13 12.9 0.0 0.4 11.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_5 PF01795.19 EKX51045.1 - 0.2 11.1 0.0 0.27 10.7 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family LRR_8 PF13855.6 EKX51046.1 - 1.7e-58 194.2 65.4 3.5e-13 49.1 4.9 6.3 3 3 4 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 EKX51046.1 - 1.7e-22 79.1 45.8 1.9e-06 28.1 2.6 8.2 3 3 6 10 10 10 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX51046.1 - 7.8e-21 74.4 0.6 1e-08 35.2 0.0 3.5 1 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 EKX51046.1 - 9.4e-12 44.8 12.1 4.9e-07 29.4 0.7 3.2 2 1 1 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 EKX51046.1 - 2.1e-10 39.7 27.3 0.095 13.3 0.3 9.0 9 0 0 9 9 9 4 Leucine Rich Repeat LRR_6 PF13516.6 EKX51046.1 - 8.8e-05 22.3 24.8 2 8.7 0.1 7.1 7 0 0 7 7 7 4 Leucine Rich repeat Myb_DNA-binding PF00249.31 EKX51047.1 - 2e-08 34.3 0.1 7.8e-08 32.4 0.1 1.9 1 1 0 1 1 1 1 Myb-like DNA-binding domain TEA PF01285.18 EKX51047.1 - 0.025 14.6 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 TEA/ATTS domain RRM_1 PF00076.22 EKX51048.1 - 3.7e-14 52.3 0.1 5.3e-14 51.8 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EKX51048.1 - 0.00012 22.0 0.2 0.00018 21.4 0.2 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EKX51048.1 - 0.0041 17.2 0.0 0.0067 16.5 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif PDEase_I PF00233.19 EKX51051.1 - 5.6e-24 85.2 12.8 4.4e-17 62.6 5.6 2.0 1 1 1 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase DUF5452 PF17533.2 EKX51051.1 - 0.044 13.9 0.1 0.048 13.7 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5452) SET PF00856.28 EKX51052.1 - 4.2e-10 40.3 0.0 6.1e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 SET domain EpsG PF14897.6 EKX51053.1 - 0.00029 20.3 12.1 0.0005 19.5 12.1 1.3 1 1 0 1 1 1 1 EpsG family ThrE_2 PF12821.7 EKX51053.1 - 0.027 14.6 0.4 0.057 13.6 0.4 1.6 1 0 0 1 1 1 0 Threonine/Serine exporter, ThrE Pkinase_Tyr PF07714.17 EKX51054.1 - 4.1e-10 39.4 0.0 4.4e-10 39.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX51054.1 - 1.5e-08 34.4 0.0 2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF2165 PF09933.9 EKX51054.1 - 0.12 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) GLTP PF08718.11 EKX51055.1 - 3.1e-36 124.9 0.1 7.5e-36 123.6 0.0 1.6 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) Ub-RnfH PF03658.14 EKX51056.1 - 0.03 14.7 0.1 0.06 13.7 0.1 1.5 1 0 0 1 1 1 0 RnfH family Ubiquitin Leo1 PF04004.13 EKX51057.1 - 9.4e-24 84.1 1.8 9.4e-24 84.1 1.8 2.7 2 0 0 2 2 2 1 Leo1-like protein STELLO PF03385.17 EKX51058.1 - 0.066 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 STELLO glycosyltransferases DNA_pol3_beta_3 PF02768.15 EKX51058.1 - 0.18 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III beta subunit, C-terminal domain Dynein_AAA_lid PF17852.1 EKX51059.1 - 6.4e-09 36.0 4.0 7.9e-09 35.7 0.7 2.9 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_8 PF12780.7 EKX51059.1 - 4.3e-05 23.0 2.4 0.14 11.5 0.0 3.7 3 0 0 3 3 3 2 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EKX51059.1 - 0.00026 20.3 0.7 0.0019 17.5 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain MT PF12777.7 EKX51059.1 - 0.0041 16.2 0.5 0.0091 15.1 0.0 1.8 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_22 PF13401.6 EKX51059.1 - 0.0082 16.4 3.3 0.86 9.9 0.0 4.5 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 EKX51059.1 - 0.044 13.7 0.0 0.32 10.9 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TniB PF05621.11 EKX51059.1 - 0.24 10.8 2.8 2.9 7.2 0.0 3.9 5 0 0 5 5 5 0 Bacterial TniB protein Pyr_redox_2 PF07992.14 EKX51060.1 - 1.8e-52 178.4 0.1 2.2e-52 178.1 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EKX51060.1 - 3.9e-13 49.8 1.0 6.5e-12 45.8 1.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EKX51060.1 - 0.00027 20.3 5.2 0.02 14.2 1.6 3.7 1 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EKX51060.1 - 0.0018 17.9 2.2 0.24 11.0 0.0 3.5 2 2 1 3 3 3 1 FAD dependent oxidoreductase Fz PF01392.22 EKX51061.1 - 0.00015 22.3 8.5 0.0002 21.9 8.5 1.2 1 0 0 1 1 1 1 Fz domain EF-hand_7 PF13499.6 EKX51063.1 - 4.6e-13 49.4 24.3 4e-06 27.2 3.3 3.3 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 EKX51063.1 - 4.7e-13 47.7 7.7 0.0024 17.3 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EKX51063.1 - 1.5e-11 43.2 3.5 0.018 14.9 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EKX51063.1 - 1.1e-10 40.5 3.5 0.077 12.5 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EKX51063.1 - 5.9e-06 26.0 4.1 0.073 12.9 0.2 4.1 4 0 0 4 4 4 2 EF-hand domain pair CsgF PF10614.9 EKX51063.1 - 0.057 13.7 0.1 0.34 11.1 0.1 2.2 2 0 0 2 2 2 0 Type VIII secretion system (T8SS), CsgF protein EF-hand_4 PF12763.7 EKX51063.1 - 0.096 12.6 2.1 2.7 8.0 0.0 3.3 3 1 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EKX51063.1 - 0.11 12.8 7.5 0.42 10.9 1.4 3.5 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF2852 PF11014.8 EKX51063.1 - 3.4 7.8 6.3 12 6.1 2.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2852) Spc24 PF08286.11 EKX51063.1 - 6.7 7.0 9.6 15 5.9 0.3 2.9 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 HSF_DNA-bind PF00447.17 EKX51064.1 - 1.1e-27 96.4 0.0 2e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding NBP1 PF08537.10 EKX51064.1 - 0.0051 16.3 5.7 0.009 15.5 5.7 1.3 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 DUF4209 PF13910.6 EKX51064.1 - 0.11 12.8 0.4 0.26 11.6 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4209) ZapB PF06005.12 EKX51064.1 - 0.15 12.5 6.5 0.38 11.2 6.5 1.7 1 0 0 1 1 1 0 Cell division protein ZapB APG6_N PF17675.1 EKX51064.1 - 6.4 7.3 11.9 0.041 14.4 2.4 2.1 2 1 0 2 2 2 0 Apg6 coiled-coil region Atg14 PF10186.9 EKX51066.1 - 0.018 14.2 36.2 0.017 14.2 22.0 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 MAD PF05557.13 EKX51066.1 - 0.025 12.9 42.1 0.046 12.1 42.1 1.4 1 1 0 1 1 1 0 Mitotic checkpoint protein Jnk-SapK_ap_N PF09744.9 EKX51066.1 - 0.033 14.4 48.6 0.068 13.4 23.1 2.7 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Spc7 PF08317.11 EKX51066.1 - 0.094 11.6 43.1 0.66 8.8 8.2 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein DegT_DnrJ_EryC1 PF01041.17 EKX51066.1 - 0.2 11.0 6.0 0.052 12.9 1.6 1.9 1 1 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Fez1 PF06818.15 EKX51066.1 - 0.25 11.7 40.8 1.6 9.1 18.9 2.1 1 1 1 2 2 2 0 Fez1 DUF2937 PF11157.8 EKX51066.1 - 0.57 9.9 7.9 0.3 10.8 3.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) DUF1664 PF07889.12 EKX51066.1 - 0.75 9.9 23.7 0.64 10.1 9.8 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Prefoldin PF02996.17 EKX51066.1 - 1.2 9.1 24.5 2.4 8.1 4.4 3.9 3 1 1 4 4 4 0 Prefoldin subunit Prominin PF05478.11 EKX51066.1 - 1.4 6.7 13.1 0.56 8.1 9.7 1.6 1 1 1 2 2 2 0 Prominin CENP-F_leu_zip PF10473.9 EKX51066.1 - 2.1 8.4 51.7 0.016 15.3 27.5 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF5082 PF16888.5 EKX51066.1 - 2.5 8.4 29.4 0.084 13.2 3.4 4.1 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) GAS PF13851.6 EKX51066.1 - 2.5 7.4 40.1 0.13 11.6 17.2 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.6 EKX51066.1 - 3.3 6.3 27.5 2.8 6.5 25.1 1.8 1 1 0 1 1 1 0 AAA domain DUF4795 PF16043.5 EKX51066.1 - 5.2 6.6 32.1 1.9 8.1 10.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) Baculo_PEP_C PF04513.12 EKX51066.1 - 5.4 7.1 8.0 3.3 7.8 1.7 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF913 PF06025.12 EKX51066.1 - 5.6 5.8 9.4 8.2 5.3 9.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4407 PF14362.6 EKX51066.1 - 6.8 5.9 26.2 13 5.0 2.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF3450 PF11932.8 EKX51066.1 - 7.1 5.9 31.1 0.85 8.9 9.3 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Tup_N PF08581.10 EKX51066.1 - 8.7 6.7 28.0 5.9 7.3 10.3 3.9 1 1 2 3 3 3 0 Tup N-terminal DUF3552 PF12072.8 EKX51066.1 - 9.8 5.5 51.7 0.086 12.2 27.1 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF3552) Neugrin PF06413.11 EKX51067.1 - 0.002 18.2 0.2 0.0036 17.3 0.2 1.3 1 0 0 1 1 1 1 Neugrin Pkinase PF00069.25 EKX51068.1 - 4.4e-36 124.6 0.0 5.3e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX51068.1 - 3.2e-22 79.0 0.0 3.7e-22 78.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX51068.1 - 3.2e-05 23.4 0.0 3.8e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EKX51068.1 - 0.00015 21.2 0.0 0.00016 21.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EKX51068.1 - 0.0013 18.7 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX51068.1 - 0.0056 15.5 0.0 0.0062 15.4 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EKX51068.1 - 0.1 12.1 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 EKX51068.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Ank_4 PF13637.6 EKX51069.1 - 1e-19 70.6 0.1 6.4e-10 39.4 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX51069.1 - 2.6e-17 63.2 0.1 1.3e-16 60.9 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX51069.1 - 4.2e-17 62.0 2.6 5.8e-12 45.6 0.5 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX51069.1 - 1.8e-16 59.7 0.0 3e-07 30.6 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EKX51069.1 - 1.2e-15 56.0 0.0 7e-06 26.0 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat DUF3117 PF11314.8 EKX51069.1 - 0.041 13.7 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3117) zf_CCCH_4 PF18345.1 EKX51070.1 - 3e-08 33.4 10.8 0.00014 21.8 4.7 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 EKX51070.1 - 6.5e-07 29.1 8.7 0.0021 17.9 0.6 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EKX51070.1 - 0.0013 19.4 5.0 0.46 11.2 0.1 2.3 1 1 1 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 EKX51070.1 - 0.0023 17.7 9.9 0.085 12.7 3.8 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger Cdc6_C PF09079.11 EKX51070.1 - 0.015 15.3 0.0 0.048 13.6 0.0 1.9 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain Phage_Gp15 PF06854.11 EKX51070.1 - 0.072 13.1 0.1 0.092 12.7 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage Gp15 protein Ank_4 PF13637.6 EKX51071.1 - 3.6e-17 62.5 0.3 6.1e-08 33.0 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX51071.1 - 3.5e-12 46.7 1.5 4.3e-06 27.2 0.2 3.2 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 EKX51071.1 - 3.3e-11 43.1 2.7 0.0013 19.1 0.4 4.5 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EKX51071.1 - 3.2e-09 36.3 0.5 0.4 11.4 0.0 5.5 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EKX51071.1 - 9.4e-09 35.4 1.1 0.00048 20.4 0.0 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) DUF3382 PF11862.8 EKX51072.1 - 0.018 15.3 1.2 0.026 14.8 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3382) TctA PF01970.16 EKX51072.1 - 0.021 13.5 12.6 0.067 11.9 0.2 2.6 2 1 1 3 3 3 0 Tripartite tricarboxylate transporter TctA family TauE PF01925.19 EKX51072.1 - 0.032 13.9 18.2 0.021 14.5 13.6 2.3 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE Glyco_transf_25 PF01755.17 EKX51073.1 - 3.5e-05 23.8 0.4 0.00075 19.4 0.2 2.6 1 1 1 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) YchF-GTPase_C PF06071.13 EKX51074.1 - 1.2e-37 127.9 0.0 3.3e-37 126.5 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EKX51074.1 - 8.4e-24 83.9 0.0 2.3e-23 82.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EKX51074.1 - 2.5e-06 27.1 0.4 7.6e-06 25.5 0.0 2.0 2 1 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EKX51074.1 - 0.0051 16.7 0.1 0.34 10.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase HDV_ag PF01517.18 EKX51074.1 - 0.045 13.5 0.7 0.086 12.6 0.7 1.4 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen MeaB PF03308.16 EKX51074.1 - 0.095 11.7 2.1 0.2 10.6 0.0 2.3 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 EKX51074.1 - 0.12 12.9 0.0 0.38 11.3 0.0 1.8 1 0 0 1 1 1 0 ABC transporter ACR_tran PF00873.19 EKX51077.1 - 0.02 12.6 0.7 0.027 12.1 0.7 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family MaoC_dehydratas PF01575.19 EKX51078.1 - 1e-16 60.6 0.1 1.3e-16 60.3 0.1 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EKX51078.1 - 7.7e-05 22.8 0.0 0.00013 22.1 0.0 1.3 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.22 EKX51078.1 - 0.1 13.0 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily Sel1 PF08238.12 EKX51079.1 - 7.8e-30 102.7 17.8 3.5e-07 30.7 0.4 6.3 6 1 0 6 6 6 4 Sel1 repeat TPR_7 PF13176.6 EKX51079.1 - 1.1e-07 31.4 9.0 0.74 10.0 0.3 5.1 4 2 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 EKX51079.1 - 2.9e-06 26.9 14.8 0.059 13.2 0.2 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX51079.1 - 5.8e-06 26.0 18.0 0.02 15.0 0.3 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX51079.1 - 6e-05 23.3 13.8 0.079 13.3 0.7 4.9 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX51079.1 - 0.00021 21.7 9.9 1.6 9.6 0.1 5.7 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX51079.1 - 0.00027 21.5 15.7 0.013 16.1 1.3 4.2 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX51079.1 - 0.0014 19.3 11.9 3.2 8.8 0.3 4.6 2 2 2 4 4 4 2 Tetratricopeptide repeat MIT PF04212.18 EKX51079.1 - 0.0016 18.4 8.4 2.8 8.1 0.4 4.6 5 0 0 5 5 5 2 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 EKX51079.1 - 0.0026 17.8 14.5 0.014 15.6 0.1 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX51079.1 - 0.041 13.8 9.4 0.67 9.9 0.0 5.1 6 1 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.20 EKX51079.1 - 0.096 13.0 0.2 6.2 7.3 0.0 3.1 2 0 0 2 2 2 0 PPR repeat TPR_19 PF14559.6 EKX51079.1 - 0.53 10.8 14.2 7.1 7.2 0.7 4.5 1 1 4 5 5 5 0 Tetratricopeptide repeat Lectin_N PF03954.14 EKX51081.1 - 0.36 10.6 0.9 0.79 9.5 0.9 1.5 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Ank_4 PF13637.6 EKX51082.1 - 1.8e-17 63.4 0.1 6.7e-10 39.3 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX51082.1 - 1.9e-12 47.2 0.1 5.8e-11 42.4 0.0 1.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX51082.1 - 1.4e-11 43.5 0.1 4.2e-06 26.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EKX51082.1 - 6.6e-11 42.7 0.0 7.5e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX51082.1 - 2.1e-10 40.5 0.1 0.00022 21.5 0.1 2.5 3 0 0 3 3 3 2 Ankyrin repeat HECT PF00632.25 EKX51083.1 - 2.1e-52 178.5 0.0 3e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ANAPC10 PF03256.16 EKX51084.1 - 6.6e-18 65.0 0.0 1.1e-08 34.9 0.0 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex, subunit 10 (APC10) Ank_4 PF13637.6 EKX51084.1 - 1.7e-11 44.4 0.7 0.00052 20.5 0.1 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX51084.1 - 9e-08 32.6 0.0 3.1e-07 30.9 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) F5_F8_type_C PF00754.25 EKX51084.1 - 1.1e-06 28.8 0.0 0.0047 17.0 0.0 3.2 3 0 0 3 3 3 2 F5/8 type C domain Ank_5 PF13857.6 EKX51084.1 - 1.5e-06 28.3 0.2 0.0011 19.2 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) SPRY PF00622.28 EKX51084.1 - 0.00058 20.0 0.4 0.0014 18.8 0.4 1.6 1 0 0 1 1 1 1 SPRY domain Ank_3 PF13606.6 EKX51084.1 - 0.0031 17.9 0.1 3.1 8.7 0.1 3.7 3 0 0 3 3 3 1 Ankyrin repeat LCM PF04072.14 EKX51085.1 - 5.7e-17 62.3 0.4 1.1e-15 58.1 0.4 2.2 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase Ras PF00071.22 EKX51086.1 - 8.2e-56 188.1 0.4 9.8e-56 187.8 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EKX51086.1 - 1.6e-37 128.3 0.1 3.8e-37 127.1 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EKX51086.1 - 9e-15 54.6 0.2 1.1e-14 54.3 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EKX51086.1 - 2.4e-05 24.0 0.1 4.3e-05 23.1 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EKX51086.1 - 3.9e-05 23.7 0.1 7.5e-05 22.8 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EKX51086.1 - 0.00047 19.6 0.0 0.00077 18.9 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EKX51086.1 - 0.00049 20.0 0.5 0.2 11.5 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase PduV-EutP PF10662.9 EKX51086.1 - 0.0089 15.8 0.1 4.1 7.1 0.0 2.1 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 EKX51086.1 - 0.014 15.1 0.3 0.086 12.6 0.3 2.1 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 EKX51086.1 - 0.049 13.1 0.8 0.062 12.7 0.1 1.6 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF1043 PF06295.12 EKX51086.1 - 0.056 13.5 0.8 0.078 13.0 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) ATPase_2 PF01637.18 EKX51086.1 - 0.074 13.0 0.3 0.16 11.8 0.3 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea zf-RING_UBOX PF13445.6 EKX51088.1 - 0.00011 22.1 6.3 0.00028 20.9 6.3 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EKX51088.1 - 0.0016 18.6 10.5 0.015 15.5 10.6 2.2 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EKX51088.1 - 0.0017 18.2 11.9 0.0029 17.4 11.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EKX51088.1 - 0.0084 15.9 9.9 0.0084 15.9 9.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX51088.1 - 0.012 15.9 13.3 0.042 14.2 13.3 1.9 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 EKX51088.1 - 1.1 9.1 13.8 0.6 10.0 8.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EKX51088.1 - 7.4 6.4 12.9 49 3.8 13.1 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 EKX51089.1 - 1.9e-29 101.3 0.0 3.6e-15 55.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EKX51089.1 - 0.00051 20.0 0.4 0.042 13.9 0.1 2.3 2 0 0 2 2 2 1 RNA binding motif DbpA PF03880.15 EKX51089.1 - 0.072 13.1 0.0 0.18 11.9 0.0 1.7 2 0 0 2 2 2 0 DbpA RNA binding domain RRM_5 PF13893.6 EKX51089.1 - 0.1 12.2 0.0 0.68 9.5 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Presenilin PF01080.17 EKX51089.1 - 7.5 5.2 8.4 9.7 4.8 8.4 1.1 1 0 0 1 1 1 0 Presenilin CMAS PF02353.20 EKX51092.1 - 2.8e-06 26.8 0.1 3.4e-06 26.6 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EKX51092.1 - 1.3e-05 25.8 0.3 4e-05 24.2 0.2 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX51092.1 - 1.9e-05 24.6 0.0 2.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EKX51092.1 - 9.4e-05 21.9 0.8 0.00012 21.6 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 EKX51092.1 - 0.00011 21.9 0.4 0.00015 21.4 0.4 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_11 PF08241.12 EKX51092.1 - 0.00012 22.7 0.3 0.0013 19.3 0.1 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 EKX51092.1 - 0.0024 17.9 0.0 0.0031 17.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 EKX51092.1 - 0.0033 17.0 0.2 0.0056 16.2 0.2 1.4 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 EKX51092.1 - 0.0066 16.3 0.0 0.0089 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EKX51092.1 - 0.031 13.8 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.20 EKX51092.1 - 0.039 13.0 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MTS PF05175.14 EKX51092.1 - 0.047 13.2 0.5 0.066 12.7 0.5 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.12 EKX51092.1 - 0.075 13.8 0.0 0.11 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 EKX51092.1 - 0.15 12.0 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain RCC1 PF00415.18 EKX51094.1 - 2.6e-50 168.8 18.3 1.9e-17 63.6 0.9 6.1 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX51094.1 - 4.7e-24 83.6 21.1 8.6e-09 35.0 1.0 4.5 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat DUF4716 PF15837.5 EKX51096.1 - 1 9.5 3.5 0.33 11.0 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4716) Aa_trans PF01490.18 EKX51097.1 - 5.5e-13 48.4 17.4 2.4e-09 36.4 1.2 2.8 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein DUF962 PF06127.11 EKX51097.1 - 0.14 12.2 0.7 1.3 9.1 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF962) Peptidase_S24 PF00717.23 EKX51098.1 - 4.2e-10 39.4 0.0 1.8e-09 37.4 0.0 2.0 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EKX51098.1 - 4.6e-09 36.2 0.0 1.2e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 Ank_2 PF12796.7 EKX51099.1 - 5.9e-25 87.7 0.9 1.3e-05 25.7 0.1 5.8 5 0 0 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX51099.1 - 2.7e-14 53.3 6.7 0.016 15.8 0.0 7.1 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX51099.1 - 6.5e-13 47.6 3.0 1.5 9.6 0.0 8.9 9 0 0 9 9 8 2 Ankyrin repeat Ank PF00023.30 EKX51099.1 - 3.2e-09 36.8 4.1 0.95 10.0 0.0 7.8 8 0 0 8 8 8 1 Ankyrin repeat EF-hand_7 PF13499.6 EKX51099.1 - 4.2e-08 33.5 0.4 1.1e-07 32.1 0.4 1.8 1 0 0 1 1 1 1 EF-hand domain pair Ank_5 PF13857.6 EKX51099.1 - 1.8e-06 28.1 8.0 1.1 9.7 0.0 7.9 8 0 0 8 8 8 2 Ankyrin repeats (many copies) EF-hand_1 PF00036.32 EKX51099.1 - 0.0017 17.8 3.5 0.46 10.2 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EKX51099.1 - 0.0062 16.4 0.2 0.37 10.8 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 EKX51099.1 - 0.015 15.1 0.1 0.061 13.2 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain pair C2 PF00168.30 EKX51099.1 - 0.17 12.2 0.1 0.44 10.9 0.1 1.7 1 0 0 1 1 1 0 C2 domain Ribosomal_60s PF00428.19 EKX51099.1 - 0.28 11.8 4.9 1.3 9.7 4.9 2.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Ion_trans PF00520.31 EKX51100.1 - 5.2e-83 278.0 67.2 2.1e-29 102.5 13.0 4.5 4 0 0 4 4 4 4 Ion transport protein zf-ribbon_3 PF13248.6 EKX51100.1 - 0.15 11.5 3.3 0.41 10.1 3.3 1.8 1 0 0 1 1 1 0 zinc-ribbon domain FAM176 PF14851.6 EKX51100.1 - 0.18 11.4 1.5 1 9.0 0.0 2.5 2 0 0 2 2 2 0 FAM176 family ISK_Channel PF02060.15 EKX51100.1 - 0.97 9.2 4.7 2.2 8.0 0.2 3.0 3 0 0 3 3 3 0 Slow voltage-gated potassium channel RWP-RK PF02042.15 EKX51101.1 - 5.5e-15 55.1 0.0 9.3e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX51101.1 - 0.17 11.7 0.5 21 5.0 0.1 2.4 1 1 1 2 2 2 0 Bacterial regulatory protein, Fis family Amino_oxidase PF01593.24 EKX51102.1 - 1.7e-65 222.1 0.0 1.9e-65 221.9 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EKX51102.1 - 7.9e-15 54.9 0.0 1.4e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EKX51102.1 - 9.8e-07 28.7 0.3 1.5e-05 24.7 0.3 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EKX51102.1 - 7.5e-06 26.4 0.0 0.18 12.4 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EKX51102.1 - 3.2e-05 23.2 0.3 0.0005 19.3 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain MCRA PF06100.11 EKX51102.1 - 0.0005 19.0 0.0 0.62 8.8 0.0 2.1 2 0 0 2 2 2 2 MCRA family FAD_oxidored PF12831.7 EKX51102.1 - 0.00086 18.8 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EKX51102.1 - 0.0026 17.1 0.3 0.0045 16.3 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EKX51102.1 - 0.006 15.9 0.1 0.013 14.7 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EKX51102.1 - 0.0062 15.8 0.2 0.011 15.0 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EKX51102.1 - 0.016 13.9 0.4 0.025 13.3 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein N6_N4_Mtase PF01555.18 EKX51103.1 - 3.1e-08 33.6 0.0 4.9e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 DNA methylase HTH_Tnp_Tc5 PF03221.16 EKX51104.1 - 2.8e-09 36.9 0.3 1.2e-08 34.8 0.1 2.1 2 1 1 3 3 3 1 Tc5 transposase DNA-binding domain SKA2 PF16740.5 EKX51104.1 - 0.0064 16.3 0.2 0.014 15.2 0.2 1.5 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 SwrA PF17423.2 EKX51104.1 - 0.028 14.4 0.1 0.053 13.5 0.1 1.4 1 0 0 1 1 1 0 Swarming motility protein HTH_ABP1_N PF18107.1 EKX51104.1 - 0.083 12.6 0.4 0.36 10.6 0.0 2.1 2 0 0 2 2 2 0 Fission yeast centromere protein N-terminal domain OmpH PF03938.14 EKX51104.1 - 0.096 13.0 3.6 0.36 11.2 0.7 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) HMMR_N PF15905.5 EKX51104.1 - 0.1 12.1 5.0 1.1 8.7 4.3 2.0 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal FlaC_arch PF05377.11 EKX51104.1 - 0.1 13.0 0.9 0.31 11.5 0.9 1.8 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Glyco_tran_28_C PF04101.16 EKX51106.1 - 3.2e-05 24.0 0.0 5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 EKX51106.1 - 0.00025 20.0 0.1 0.00073 18.5 0.0 1.6 1 1 1 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.20 EKX51106.1 - 0.0062 16.6 0.0 0.018 15.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Na_Ca_ex PF01699.24 EKX51107.1 - 5.9e-45 152.9 28.2 1.1e-24 87.1 10.0 2.5 2 1 0 2 2 2 2 Sodium/calcium exchanger protein Calx-beta PF03160.14 EKX51107.1 - 1.1e-27 96.1 2.1 1e-16 60.9 0.2 2.5 2 0 0 2 2 2 2 Calx-beta domain YaeQ PF07152.12 EKX51107.1 - 0.029 14.0 0.0 0.066 12.8 0.0 1.5 1 0 0 1 1 1 0 YaeQ protein DUF4349 PF14257.6 EKX51107.1 - 0.12 11.8 0.0 0.86 9.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) ABM PF03992.16 EKX51109.1 - 1.1e-08 35.0 0.0 1.5e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ABM PF03992.16 EKX51110.1 - 2.2e-14 53.3 0.1 2.5e-14 53.1 0.1 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase PH_2 PF08458.10 EKX51110.1 - 0.013 15.9 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 0 Plant pleckstrin homology-like region Pox_P35 PF03213.14 EKX51111.1 - 0.29 10.3 1.0 0.83 8.8 0.5 1.7 2 0 0 2 2 2 0 Poxvirus P35 protein OmpH PF03938.14 EKX51112.1 - 0.1 12.9 2.5 0.13 12.6 0.9 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) RRM_1 PF00076.22 EKX51113.1 - 3e-19 68.6 0.4 8.8e-19 67.1 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EKX51113.1 - 0.00025 21.1 0.1 0.0017 18.5 0.0 2.5 1 1 1 2 2 2 1 RNA recognition motif ATG16 PF08614.11 EKX51113.1 - 0.013 15.7 10.7 0.013 15.7 10.7 5.3 2 1 3 5 5 5 0 Autophagy protein 16 (ATG16) DUF1700 PF08006.11 EKX51113.1 - 0.21 11.1 1.4 0.59 9.7 1.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) NPV_P10 PF05531.12 EKX51113.1 - 9.9 6.7 9.9 12 6.4 0.3 3.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein mTERF PF02536.14 EKX51114.1 - 4e-43 147.5 4.4 5.8e-28 97.7 1.5 2.2 1 1 1 2 2 2 2 mTERF EF-hand_7 PF13499.6 EKX51114.1 - 1.3e-07 32.0 6.6 0.00019 21.8 0.5 2.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX51114.1 - 5.5e-07 29.0 0.6 2.3e-06 27.1 0.3 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EKX51114.1 - 8.4e-07 28.1 2.1 1.2e-06 27.7 1.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 EKX51114.1 - 1.4e-06 27.5 0.9 2.7e-06 26.6 0.9 1.5 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 EKX51114.1 - 1.2e-05 25.0 0.1 1.2e-05 25.0 0.1 3.1 3 1 1 4 4 4 1 EF-hand domain pair Bac_rhodopsin PF01036.18 EKX51115.1 - 2.6e-37 128.5 20.8 3.3e-37 128.2 20.8 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF2244 PF10003.9 EKX51115.1 - 1.5 8.4 9.1 0.31 10.7 0.3 2.6 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) DUF3278 PF11683.8 EKX51115.1 - 2 8.5 7.6 0.64 10.1 1.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3278) Vps51 PF08700.11 EKX51116.1 - 9.9e-10 38.4 0.0 2.8e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 Vps51/Vps67 ARL6IP6 PF15062.6 EKX51117.1 - 0.066 13.3 0.0 2 8.6 0.0 2.2 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix UvrB PF12344.8 EKX51117.1 - 0.095 12.6 0.4 19 5.2 0.0 2.4 2 0 0 2 2 2 0 Ultra-violet resistance protein B CYYR1 PF10873.8 EKX51117.1 - 0.099 13.1 0.1 0.13 12.7 0.1 1.2 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 DUF456 PF04306.13 EKX51117.1 - 0.28 11.4 7.1 0.47 10.7 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Ion_trans PF00520.31 EKX51118.1 - 5e-19 68.5 17.8 1e-18 67.5 17.8 1.5 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX51118.1 - 7.2e-14 51.5 0.7 7.2e-14 51.5 0.7 2.0 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 EKX51118.1 - 1.2e-12 47.8 0.1 5.1e-12 45.7 0.0 2.1 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain FHIPEP PF00771.20 EKX51120.1 - 0.04 12.4 0.2 0.046 12.2 0.2 1.2 1 0 0 1 1 1 0 FHIPEP family Peptidase_C58 PF03543.14 EKX51120.1 - 0.065 12.9 1.9 0.087 12.5 1.9 1.1 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen Cdh1_DBD_1 PF18196.1 EKX51120.1 - 0.13 12.6 5.2 0.18 12.1 5.2 1.3 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 DUF724 PF05266.14 EKX51120.1 - 2.6 7.8 7.9 2.3 8.0 6.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) PA PF02225.22 EKX51121.1 - 2.7e-08 33.7 0.0 7.4e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 PA domain Tudor_4 PF18358.1 EKX51121.1 - 0.1 12.2 0.1 0.28 10.8 0.1 1.7 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain PA PF02225.22 EKX51122.1 - 9.7e-05 22.3 0.0 0.00021 21.3 0.0 1.6 1 0 0 1 1 1 1 PA domain DUF3328 PF11807.8 EKX51122.1 - 0.26 11.0 0.4 0.44 10.3 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DUF4131 PF13567.6 EKX51122.1 - 7.9 6.1 6.7 14 5.3 6.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Ion_trans PF00520.31 EKX51123.1 - 4e-34 118.0 19.1 5.4e-34 117.5 19.1 1.2 1 0 0 1 1 1 1 Ion transport protein EF-hand_6 PF13405.6 EKX51123.1 - 1.1e-05 24.9 0.0 0.0013 18.5 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EKX51123.1 - 0.00023 20.5 0.2 0.0012 18.2 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 EKX51123.1 - 0.00041 19.7 0.0 0.0016 17.8 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EKX51123.1 - 0.0012 19.2 0.1 0.025 15.0 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain pair PH PF00169.29 EKX51123.1 - 0.0088 16.5 0.1 0.018 15.5 0.1 1.5 1 0 0 1 1 1 1 PH domain dsDNA_bind PF01984.20 EKX51123.1 - 0.012 15.8 0.4 0.029 14.6 0.4 1.5 1 0 0 1 1 1 0 Double-stranded DNA-binding domain EF-hand_8 PF13833.6 EKX51123.1 - 0.015 15.2 0.0 0.31 10.9 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair Macro PF01661.21 EKX51123.1 - 0.1 12.7 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Macro domain Phasin PF05597.11 EKX51123.1 - 0.12 12.4 0.9 0.29 11.2 0.9 1.6 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF3242 PF11586.8 EKX51123.1 - 0.13 12.0 0.1 0.51 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3242) DUF2201_N PF13203.6 EKX51123.1 - 0.27 10.8 0.6 0.47 10.0 0.6 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Aminotran_1_2 PF00155.21 EKX51124.1 - 1.1e-41 143.3 0.0 1.3e-36 126.5 0.2 2.9 1 1 1 2 2 2 2 Aminotransferase class I and II Radical_SAM_C PF16199.5 EKX51125.1 - 3.7e-33 113.4 0.1 7.9e-33 112.3 0.1 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EKX51125.1 - 3.8e-18 66.4 0.1 4.9e-17 62.8 0.0 2.6 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 EKX51125.1 - 4.6e-12 46.2 0.1 8.8e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EKX51125.1 - 2.7e-06 27.4 0.1 6.2e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EKX51125.1 - 0.0007 20.0 0.1 0.0013 19.1 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EKX51125.1 - 0.028 14.4 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein LRR_6 PF13516.6 EKX51126.1 - 1.9e-10 39.9 13.0 0.55 10.4 0.1 7.2 7 0 0 7 7 7 5 Leucine Rich repeat LRR_4 PF12799.7 EKX51126.1 - 5.1e-05 23.6 17.5 0.064 13.7 3.0 6.7 5 2 3 8 8 8 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX51126.1 - 0.00085 19.0 18.6 0.94 9.3 2.5 6.4 5 1 2 7 7 7 3 Leucine rich repeat LRR_1 PF00560.33 EKX51126.1 - 0.0095 16.4 15.2 12 7.0 0.0 7.7 6 2 0 6 6 6 1 Leucine Rich Repeat GST_N_3 PF13417.6 EKX51127.1 - 3.3e-19 69.0 0.0 6.1e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EKX51127.1 - 7.2e-17 61.5 0.0 1.2e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EKX51127.1 - 1.2e-15 57.6 0.0 2.1e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EKX51127.1 - 1.5e-11 44.2 0.2 8.3e-11 41.8 0.1 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EKX51127.1 - 2.6e-08 33.9 0.0 6.4e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EKX51127.1 - 9.3e-06 26.0 0.0 2.3e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_3 PF14497.6 EKX51127.1 - 1.7e-05 24.9 0.0 4.2e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EKX51127.1 - 0.00014 22.0 0.0 0.00029 21.0 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_N_4 PF17172.4 EKX51127.1 - 0.0029 18.3 0.0 0.0077 17.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain RWP-RK PF02042.15 EKX51128.1 - 6.4e-14 51.7 0.0 1.1e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain Sushi PF00084.20 EKX51129.1 - 2e-19 69.9 30.1 0.00038 21.0 0.5 7.8 7 1 0 7 7 7 6 Sushi repeat (SCR repeat) DUF61 PF01886.16 EKX51129.1 - 0.14 12.2 0.8 1.5 8.9 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF61 Noelin-1 PF12308.8 EKX51129.1 - 2 8.4 4.0 1.5 8.8 0.5 2.5 2 0 0 2 2 2 0 Neurogenesis glycoprotein RRF PF01765.19 EKX51129.1 - 3.4 7.6 7.1 3.6 7.5 3.5 2.3 2 0 0 2 2 2 0 Ribosome recycling factor DUF5446 PF17522.2 EKX51129.1 - 6.7 7.0 6.4 4.6 7.5 2.8 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5446) Methyltransf_16 PF10294.9 EKX51130.1 - 1.5e-18 67.1 0.1 2.1e-18 66.6 0.1 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 EKX51130.1 - 1.2e-08 35.6 0.1 3.6e-07 30.8 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.14 EKX51130.1 - 3.3e-07 30.0 0.0 9.2e-07 28.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 EKX51130.1 - 8.4e-06 25.4 0.2 1.3e-05 24.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EKX51130.1 - 2.1e-05 24.3 0.0 5.8e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX51130.1 - 0.00018 22.2 0.0 0.00032 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EKX51130.1 - 0.0031 16.7 0.0 0.0038 16.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase PCMT PF01135.19 EKX51130.1 - 0.0053 16.5 0.0 0.0084 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14 PF08704.10 EKX51130.1 - 0.0077 15.9 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_11 PF08241.12 EKX51130.1 - 0.012 16.2 0.1 0.027 15.1 0.0 1.6 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 EKX51130.1 - 0.014 15.3 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 EKX51130.1 - 0.02 15.9 0.1 0.046 14.8 0.0 1.6 2 0 0 2 2 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 EKX51130.1 - 0.03 13.7 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Met_10 PF02475.16 EKX51130.1 - 0.091 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein TRM PF02005.16 EKX51130.1 - 0.097 11.8 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Ion_trans PF00520.31 EKX51131.1 - 9.1e-24 84.0 5.1 1.3e-23 83.5 5.1 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX51131.1 - 1.1e-14 54.2 1.3 2.1e-14 53.2 1.3 1.5 1 0 0 1 1 1 1 Ion channel PKD_channel PF08016.12 EKX51131.1 - 0.0058 15.4 0.1 0.01 14.6 0.1 1.3 1 0 0 1 1 1 1 Polycystin cation channel DUF2730 PF10805.8 EKX51131.1 - 0.023 14.8 0.2 0.047 13.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) fn3 PF00041.21 EKX51132.1 - 6.2e-11 42.5 4.0 0.044 14.1 0.0 6.2 6 2 0 6 6 6 4 Fibronectin type III domain NHL PF01436.21 EKX51132.1 - 0.00022 21.1 0.0 0.0021 18.0 0.0 2.7 2 0 0 2 2 2 1 NHL repeat Ephrin_rec_like PF07699.13 EKX51132.1 - 0.015 15.1 22.5 0.38 10.6 11.7 3.0 2 1 0 2 2 2 0 Putative ephrin-receptor like HTH_Tnp_Tc5 PF03221.16 EKX51133.1 - 0.15 12.1 0.1 0.36 10.9 0.1 1.6 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain YebO PF13974.6 EKX51133.1 - 1.5 8.9 5.2 30 4.8 4.0 3.0 2 0 0 2 2 2 0 YebO-like protein MAP65_ASE1 PF03999.12 EKX51134.1 - 0.015 14.0 17.9 0.017 13.9 17.9 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Med15 PF09606.10 EKX51134.1 - 0.44 9.2 40.0 0.69 8.5 40.0 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Macoilin PF09726.9 EKX51134.1 - 0.8 8.2 12.7 0.91 8.0 12.7 1.2 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 EKX51134.1 - 1.3 7.6 16.9 1.4 7.6 16.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 EKX51134.1 - 2.9 6.5 19.1 5 5.8 19.1 1.4 1 0 0 1 1 1 0 Presenilin SMYLE_N PF18615.1 EKX51134.1 - 4.5 6.7 16.4 6.4 6.2 16.4 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain WW PF00397.26 EKX51135.1 - 8.5e-09 35.4 1.4 1.1e-08 35.0 1.4 1.2 1 0 0 1 1 1 1 WW domain HTH_Tnp_Tc5 PF03221.16 EKX51138.1 - 8.5e-10 38.5 0.1 2e-09 37.3 0.1 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain PDZ_6 PF17820.1 EKX51139.1 - 1.4e-12 47.2 0.0 2.9e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX51139.1 - 1e-08 35.4 0.2 1.8e-08 34.6 0.2 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX51139.1 - 5.2e-08 33.1 0.1 9e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX51139.1 - 0.096 12.7 0.0 0.16 11.9 0.0 1.5 1 1 0 1 1 1 0 Tricorn protease PDZ domain Thioredoxin PF00085.20 EKX51140.1 - 1.2e-36 124.8 0.0 8e-21 74.0 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 EKX51140.1 - 4.6e-12 46.2 0.3 1.8e-09 37.7 0.1 3.7 2 1 2 4 4 4 1 Thioredoxin-like domain AhpC-TSA PF00578.21 EKX51140.1 - 1.1e-08 35.0 0.3 0.00057 19.8 0.0 2.9 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_8 PF13905.6 EKX51140.1 - 1.5e-06 28.4 0.1 0.004 17.5 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.13 EKX51140.1 - 3.2e-06 26.7 0.2 0.0012 18.3 0.0 2.8 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EKX51140.1 - 1.2e-05 25.4 0.0 0.067 13.4 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EKX51140.1 - 2.9e-05 24.5 1.4 0.85 10.1 0.1 3.9 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_4 PF13462.6 EKX51140.1 - 0.029 14.5 1.7 27 4.9 0.0 3.8 4 1 0 4 4 4 0 Thioredoxin NUDIX PF00293.28 EKX51143.1 - 7.4e-20 71.3 0.0 1e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EKX51143.1 - 6.8e-05 22.8 0.0 0.00011 22.2 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain MAP70 PF07058.11 EKX51144.1 - 2.3 6.8 7.5 2.6 6.7 7.5 1.0 1 0 0 1 1 1 0 Microtubule-associated protein 70 p450 PF00067.22 EKX51145.1 - 7.1e-57 193.2 0.0 9.1e-57 192.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TMEM144 PF07857.12 EKX51146.1 - 3e-11 42.9 19.1 4.2e-10 39.1 19.1 2.2 1 1 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 EKX51146.1 - 1.3e-10 41.1 0.8 1.3e-10 41.1 0.8 2.3 2 1 0 2 2 2 1 Sugar transport protein MarC PF01914.17 EKX51146.1 - 0.0046 16.4 0.6 0.16 11.3 0.7 2.6 2 0 0 2 2 2 1 MarC family integral membrane protein C2 PF00168.30 EKX51148.1 - 1.5e-10 41.3 0.0 4.1e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 C2 domain SCNM1_acidic PF15805.5 EKX51148.1 - 0.17 11.6 0.6 0.42 10.4 0.6 1.6 1 0 0 1 1 1 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 Thioredoxin_2 PF13098.6 EKX51148.1 - 0.23 11.9 0.0 0.79 10.2 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like domain Glycos_transf_3 PF00591.21 EKX51151.1 - 6.9e-38 130.7 1.3 9.5e-38 130.2 1.3 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EKX51151.1 - 6.8e-20 70.7 0.2 3e-19 68.6 0.3 2.1 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain PYNP_C PF07831.13 EKX51151.1 - 3e-17 62.0 0.0 9.7e-17 60.4 0.0 1.9 2 0 0 2 2 2 1 Pyrimidine nucleoside phosphorylase C-terminal domain Biotin_lipoyl PF00364.22 EKX51151.1 - 0.069 13.0 0.0 0.52 10.2 0.0 2.4 3 0 0 3 3 3 0 Biotin-requiring enzyme Pox_A_type_inc PF04508.12 EKX51152.1 - 0.018 14.8 0.6 0.047 13.5 0.6 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat BiPBP_C PF06832.12 EKX51152.1 - 0.042 13.9 0.0 0.086 12.9 0.0 1.5 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family CE2_N PF17996.1 EKX51152.1 - 0.078 13.0 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal EF-hand_5 PF13202.6 EKX51154.1 - 5.8e-05 22.4 0.0 0.00012 21.4 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 EKX51154.1 - 0.0087 15.5 0.0 0.02 14.4 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EKX51154.1 - 0.054 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 EKX51154.1 - 0.18 12.3 0.0 0.43 11.1 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair AAA_23 PF13476.6 EKX51155.1 - 0.0096 16.4 6.3 0.012 16.2 6.3 1.1 1 0 0 1 1 1 1 AAA domain DUF3347 PF11827.8 EKX51155.1 - 0.011 16.0 8.0 0.013 15.7 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) ART-PolyVal PF18760.1 EKX51155.1 - 0.051 14.6 0.7 0.059 14.4 0.7 1.2 1 0 0 1 1 1 0 ADP-Ribosyltransferase in polyvalent proteins Ly49 PF08391.10 EKX51155.1 - 0.22 11.9 3.5 0.3 11.4 3.5 1.3 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region SIN1 PF05422.12 EKX51155.1 - 1 9.9 10.2 1.8 9.1 10.2 1.5 1 1 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) AAA_11 PF13086.6 EKX51155.1 - 2.4 7.9 9.8 3 7.6 9.8 1.0 1 0 0 1 1 1 0 AAA domain Arm PF00514.23 EKX51156.1 - 5.2e-12 45.4 1.6 2.2e-06 27.5 0.0 4.2 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EKX51156.1 - 6.2e-07 29.7 0.1 2.9e-05 24.4 0.0 2.7 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 EKX51156.1 - 5.3e-06 26.2 0.1 3.4e-05 23.7 0.0 2.5 2 0 0 2 2 2 1 HEAT repeat Arm_2 PF04826.13 EKX51156.1 - 0.0028 17.1 0.0 0.32 10.4 0.0 2.8 2 1 1 3 3 3 1 Armadillo-like DUF1636 PF07845.11 EKX51156.1 - 0.45 11.0 2.5 9.9 6.6 0.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1636) Ephrin_rec_like PF07699.13 EKX51157.1 - 4.3e-23 80.8 21.8 1.1e-12 47.5 6.4 3.5 2 0 0 2 2 2 2 Putative ephrin-receptor like DUF3456 PF11938.8 EKX51157.1 - 1e-19 71.6 8.8 1.7e-19 70.8 8.8 1.3 1 0 0 1 1 1 1 TLR4 regulator and MIR-interacting MSAP DUF4215 PF13948.6 EKX51157.1 - 1.9e-17 63.4 72.2 2e-06 28.1 10.7 6.5 4 1 3 7 7 7 4 Domain of unknown function (DUF4215) TNFR_c6 PF00020.18 EKX51157.1 - 0.096 13.1 21.9 1.4 9.4 3.0 5.9 3 2 0 3 3 3 0 TNFR/NGFR cysteine-rich region Gelsolin PF00626.22 EKX51158.1 - 8.7e-11 41.6 0.1 2e-10 40.4 0.1 1.6 1 0 0 1 1 1 1 Gelsolin repeat NAD_binding_8 PF13450.6 EKX51158.1 - 8.9e-10 38.7 0.1 2e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain EF-hand_7 PF13499.6 EKX51158.1 - 3.9e-07 30.4 0.1 2.6e-06 27.8 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX51158.1 - 3.7e-06 26.4 0.3 8.6e-05 22.2 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain Amino_oxidase PF01593.24 EKX51158.1 - 1.7e-05 24.3 0.4 0.21 10.9 0.0 2.8 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase EF-hand_1 PF00036.32 EKX51158.1 - 5.2e-05 22.5 0.1 0.015 14.8 0.0 3.2 3 0 0 3 3 3 1 EF hand Pyr_redox_2 PF07992.14 EKX51158.1 - 0.015 14.6 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EKX51158.1 - 0.11 11.1 0.2 0.16 10.6 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Sina PF03145.16 EKX51158.1 - 1.2 9.0 5.7 1.6 8.7 4.3 1.9 1 1 0 1 1 1 0 Seven in absentia protein family MAGI_u5 PF16666.5 EKX51159.1 - 0.091 12.9 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 Unstructured region on MAGI Atg14 PF10186.9 EKX51159.1 - 0.89 8.6 8.0 1.2 8.2 8.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ABC_tran_CTD PF16326.5 EKX51159.1 - 3 8.2 10.8 0.19 12.0 1.9 2.9 3 0 0 3 3 3 0 ABC transporter C-terminal domain PTPlike_phytase PF14566.6 EKX51159.1 - 3.8 7.6 7.4 10 6.2 7.4 1.8 1 1 0 1 1 1 0 Inositol hexakisphosphate RRM_1 PF00076.22 EKX51160.1 - 6.5e-31 106.0 0.2 1.1e-14 54.0 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EKX51160.1 - 6e-12 45.5 0.3 3.2e-05 23.9 0.1 2.6 2 2 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EKX51160.1 - 0.0055 16.7 0.3 3.1 7.9 0.1 2.2 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif SRP9-21 PF05486.12 EKX51161.1 - 0.054 13.9 6.7 0.43 11.0 0.0 3.5 3 1 0 3 3 3 0 Signal recognition particle 9 kDa protein (SRP9) MIF4G PF02854.19 EKX51162.1 - 1.3e-62 211.2 15.9 2.8e-30 105.6 0.8 3.5 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 EKX51162.1 - 3.7e-20 73.1 0.4 3.7e-20 73.1 0.4 4.4 6 0 0 6 6 6 1 Up-frameshift suppressor 2 Ion_trans_2 PF07885.16 EKX51163.1 - 4.5e-15 55.4 5.1 6.2e-15 54.9 5.1 1.2 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EKX51163.1 - 1.2e-13 50.9 1.5 1.6e-13 50.5 1.5 1.2 1 0 0 1 1 1 1 Ion transport protein DUF3357 PF11837.8 EKX51163.1 - 0.011 16.2 0.1 0.025 15.1 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) TMEM190 PF15431.6 EKX51164.1 - 0.086 13.0 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Transmembrane protein 190 Gln_amidase PF15644.6 EKX51164.1 - 0.093 13.8 0.0 0.43 11.6 0.0 2.2 1 0 0 1 1 1 0 Papain fold toxin 1, glutamine deamidase DUF1990 PF09348.10 EKX51165.1 - 3.1e-08 33.8 0.0 8.6e-08 32.4 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1990) Metallophos PF00149.28 EKX51166.1 - 2e-07 31.7 0.0 3.9e-07 30.8 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Connexin50 PF03509.14 EKX51168.1 - 0.13 13.1 1.2 0.67 10.8 0.0 2.5 2 0 0 2 2 2 0 Gap junction alpha-8 protein (Cx50) CBM_20 PF00686.19 EKX51169.1 - 7e-28 96.4 0.0 1.2e-14 54.0 0.0 2.3 2 0 0 2 2 2 2 Starch binding domain Med13_N PF11597.8 EKX51170.1 - 0.037 13.4 0.1 0.062 12.7 0.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 N-terminal FHA PF00498.26 EKX51171.1 - 2.1e-12 47.2 0.2 3.9e-12 46.3 0.2 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EKX51171.1 - 1.9e-06 28.1 0.0 6.4e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain 2OG-FeII_Oxy_3 PF13640.6 EKX51172.1 - 1.7e-17 64.1 0.0 2.6e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF5106 PF17127.4 EKX51172.1 - 0.083 13.2 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5106) Ald_deCOase PF11266.8 EKX51172.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Long-chain fatty aldehyde decarbonylase SAM_1 PF00536.30 EKX51173.1 - 3.9e-10 40.0 0.8 6e-10 39.4 0.8 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EKX51173.1 - 1.9e-08 34.3 0.3 3.4e-08 33.5 0.3 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_3 PF18016.1 EKX51173.1 - 1.1e-06 28.4 0.1 1.8e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 EKX51173.1 - 0.00045 20.1 0.0 0.00074 19.4 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain LRR_8 PF13855.6 EKX51174.1 - 1.7e-47 159.0 69.1 3.7e-09 36.2 5.8 9.7 4 2 8 12 12 12 12 Leucine rich repeat LRR_4 PF12799.7 EKX51174.1 - 1.5e-35 120.6 70.4 6e-08 32.9 2.1 12.9 4 2 12 17 17 17 16 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX51174.1 - 4.3e-05 23.1 28.0 0.023 14.2 3.3 5.7 2 1 4 7 7 7 5 Leucine-rich repeat LRR_1 PF00560.33 EKX51174.1 - 0.00076 19.7 64.3 1.5 9.7 0.2 14.9 16 1 0 16 16 16 4 Leucine Rich Repeat Gal11_ABD1 PF18535.1 EKX51174.1 - 0.065 13.3 0.0 0.54 10.4 0.0 2.7 1 0 0 1 1 1 0 Gal11 activator-binding domain (ABD1) Ank_2 PF12796.7 EKX51175.1 - 2.8e-20 72.7 0.0 5.5e-09 36.5 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX51175.1 - 5e-17 60.2 0.0 0.00034 20.8 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EKX51175.1 - 6.7e-16 58.4 0.1 4.1e-07 30.4 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX51175.1 - 1.1e-15 57.2 0.4 0.00042 20.6 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EKX51175.1 - 1.8e-13 50.4 1.1 0.0009 19.5 0.0 4.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) EF-hand_7 PF13499.6 EKX51176.1 - 8e-10 39.0 0.8 9.1e-10 38.9 0.8 1.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX51176.1 - 4.8e-09 35.4 1.9 1.3e-05 24.7 0.2 2.7 1 1 1 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EKX51176.1 - 1.8e-08 33.3 2.3 5e-05 22.6 0.1 2.4 2 1 1 3 3 3 2 EF hand EF-hand_8 PF13833.6 EKX51176.1 - 1.3e-06 28.1 3.3 6.8e-05 22.6 0.3 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX51176.1 - 0.00088 18.7 4.4 0.0012 18.2 0.2 2.4 2 1 0 2 2 2 1 EF hand EF-hand_4 PF12763.7 EKX51176.1 - 0.0067 16.4 1.8 0.012 15.5 0.4 1.8 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand ParD_antitoxin PF03693.14 EKX51176.1 - 0.064 13.7 0.6 1.8 9.0 0.2 2.0 1 1 1 2 2 2 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH zf-BED PF02892.15 EKX51177.1 - 0.0049 16.9 1.4 0.012 15.6 1.4 1.6 1 0 0 1 1 1 1 BED zinc finger YceI PF04264.13 EKX51177.1 - 0.055 14.0 0.0 0.078 13.5 0.0 1.3 1 0 0 1 1 1 0 YceI-like domain zf-C2H2_4 PF13894.6 EKX51177.1 - 0.094 13.6 4.2 0.13 13.2 2.5 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger ABATE PF07336.11 EKX51178.1 - 0.0093 16.6 6.0 0.018 15.7 6.0 1.4 1 0 0 1 1 1 1 Putative stress-induced transcription regulator KASH_CCD PF14662.6 EKX51178.1 - 0.019 14.8 0.1 0.029 14.2 0.1 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Pyridoxal_deC PF00282.19 EKX51180.1 - 3.1e-06 26.2 0.1 3.8e-06 25.9 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Ank_2 PF12796.7 EKX51181.1 - 5.1e-41 139.1 0.0 1.8e-09 38.1 0.0 3.5 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX51181.1 - 5.6e-26 90.6 0.9 9.2e-09 35.7 0.0 4.4 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX51181.1 - 3.3e-16 59.1 0.5 4.1e-05 23.8 0.0 4.6 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX51181.1 - 6.9e-16 56.7 0.0 0.0099 16.3 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 EKX51181.1 - 5.9e-13 48.6 0.0 0.023 15.1 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Glyco_transf_41 PF13844.6 EKX51182.1 - 1.8e-60 204.7 0.4 3.9e-29 101.4 0.0 3.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_2 PF07719.17 EKX51182.1 - 2.6e-30 102.1 3.9 0.0018 18.2 0.0 8.5 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_1 PF00515.28 EKX51182.1 - 8e-28 95.1 1.3 0.00065 19.4 0.0 8.3 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 EKX51182.1 - 9.9e-24 81.5 1.3 0.00068 19.7 0.0 8.6 10 0 0 10 10 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 EKX51182.1 - 2.7e-20 72.7 14.4 2.9e-08 34.2 1.5 5.8 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 EKX51182.1 - 1.2e-19 69.7 11.5 0.00015 21.4 0.0 7.3 5 1 2 7 7 7 5 TPR repeat TPR_7 PF13176.6 EKX51182.1 - 1.8e-19 68.2 5.4 0.0027 17.6 0.1 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 EKX51182.1 - 8.7e-18 64.4 13.6 0.00011 22.4 0.0 6.5 2 1 4 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 EKX51182.1 - 2.9e-12 46.9 5.9 0.0061 17.1 0.2 4.6 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 EKX51182.1 - 3.3e-12 45.9 5.7 0.0086 16.4 0.1 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX51182.1 - 4e-12 45.9 12.9 0.15 13.0 0.3 8.4 3 2 5 8 8 8 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX51182.1 - 1.9e-09 37.1 21.3 0.089 12.7 0.1 7.8 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 EKX51182.1 - 6.6e-06 26.2 13.6 0.043 14.0 0.5 5.0 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX51182.1 - 1.5e-05 24.6 1.3 0.00087 18.7 0.3 3.0 3 1 1 4 4 4 1 MalT-like TPR region TPR_6 PF13174.6 EKX51182.1 - 2.1e-05 24.8 7.3 0.89 10.3 0.0 6.9 7 0 0 7 7 6 1 Tetratricopeptide repeat MIT PF04212.18 EKX51182.1 - 0.0018 18.3 2.2 6.5 6.9 0.1 3.8 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain BTAD PF03704.17 EKX51182.1 - 0.0022 18.5 7.0 0.038 14.4 1.0 3.9 2 1 0 3 3 3 1 Bacterial transcriptional activator domain TPR_4 PF07721.14 EKX51182.1 - 0.0022 18.4 0.4 0.55 11.0 0.4 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX51182.1 - 0.0033 17.6 2.1 4.8 7.5 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Wzy_C_2 PF11846.8 EKX51182.1 - 0.0096 15.9 3.6 5 7.0 0.1 3.2 2 1 1 3 3 3 1 Virulence factor membrane-bound polymerase, C-terminal TPR_15 PF13429.6 EKX51182.1 - 0.053 12.7 6.8 1.2 8.3 0.4 3.5 1 1 2 4 4 4 0 Tetratricopeptide repeat Acid_phosphat_B PF03767.14 EKX51182.1 - 0.15 11.6 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) TPR_21 PF09976.9 EKX51182.1 - 0.16 11.7 0.8 7 6.3 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain Endonuc-dimeris PF09124.10 EKX51182.1 - 0.18 12.0 0.0 28 5.0 0.0 2.6 2 0 0 2 2 2 0 T4 recombination endonuclease VII, dimerisation CLASP_N PF12348.8 EKX51183.1 - 7.9e-23 81.2 13.8 4.1e-09 36.3 0.1 6.4 5 1 0 5 5 5 4 CLASP N terminal HEAT PF02985.22 EKX51183.1 - 2.2e-10 39.9 10.4 0.61 10.5 0.1 8.3 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 EKX51183.1 - 2e-07 31.3 8.0 5.4 7.5 0.1 9.3 10 1 1 11 11 11 1 HEAT repeats Cnd1 PF12717.7 EKX51183.1 - 4.3e-06 26.9 18.2 0.00025 21.1 0.1 7.0 6 1 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Dopey_N PF04118.14 EKX51183.1 - 0.0087 15.2 9.3 0.12 11.4 0.0 4.9 4 2 1 5 5 5 2 Dopey, N-terminal TPR_MalT PF17874.1 EKX51183.1 - 0.017 14.5 0.0 0.017 14.5 0.0 2.9 3 0 0 3 3 3 0 MalT-like TPR region Arm PF00514.23 EKX51183.1 - 0.32 11.1 2.2 2.6 8.2 0.1 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Ank_2 PF12796.7 EKX51184.1 - 2.8e-16 59.9 6.7 9.2e-09 35.8 1.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX51184.1 - 1.1e-11 45.0 0.7 1.9e-06 28.3 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX51184.1 - 1.5e-07 31.1 0.5 1.6 9.5 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EKX51184.1 - 3.9e-07 30.2 1.5 0.00049 20.3 0.7 3.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX51184.1 - 1.4e-05 25.3 2.8 2.2 8.9 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeat DUF2552 PF10827.8 EKX51184.1 - 0.01 16.0 0.1 2.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2552) FAIM1 PF06905.13 EKX51184.1 - 0.1 12.3 0.1 0.17 11.6 0.1 1.4 1 1 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) Type2_restr_D3 PF16902.5 EKX51184.1 - 0.15 12.0 0.0 0.38 10.7 0.0 1.7 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain Ion_trans PF00520.31 EKX51185.1 - 1.1e-07 31.3 10.7 1.5e-07 30.9 10.7 1.1 1 0 0 1 1 1 1 Ion transport protein HR_lesion PF05514.11 EKX51185.1 - 0.091 12.9 3.4 0.19 11.9 3.4 1.5 1 1 0 1 1 1 0 HR-like lesion-inducing DUF4149 PF13664.6 EKX51185.1 - 2.2 8.6 7.1 17 5.8 2.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) XG_FTase PF03254.13 EKX51186.1 - 0.013 14.2 0.0 1.8 7.1 0.0 2.1 2 0 0 2 2 2 0 Xyloglucan fucosyltransferase SHIPPO-rpt PF07004.12 EKX51187.1 - 8.4e-06 26.5 4.2 0.18 12.8 0.2 3.7 3 0 0 3 3 3 3 Sperm-tail PG-rich repeat RACo_linker PF17650.1 EKX51187.1 - 0.0042 16.9 0.1 0.02 14.8 0.0 2.0 2 0 0 2 2 2 1 RACo linker region TFIIA PF03153.13 EKX51188.1 - 0.016 15.2 13.9 0.021 14.9 13.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FBP_C PF16571.5 EKX51188.1 - 0.027 14.0 0.5 0.046 13.2 0.5 1.3 1 0 0 1 1 1 0 FBP C-terminal treble-clef zinc-finger Borrelia_P83 PF05262.11 EKX51188.1 - 0.24 9.8 4.5 0.32 9.4 4.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Neur_chan_memb PF02932.16 EKX51188.1 - 0.33 11.0 2.4 0.42 10.6 2.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AT_hook PF02178.19 EKX51188.1 - 0.36 10.8 4.3 0.84 9.7 4.3 1.7 1 0 0 1 1 1 0 AT hook motif Zip PF02535.22 EKX51188.1 - 0.77 8.9 4.6 0.99 8.6 4.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.7 EKX51188.1 - 2.1 6.4 8.2 2.8 6.0 8.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 EKX51188.1 - 3.9 6.1 10.7 5.6 5.6 10.7 1.2 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 EKX51188.1 - 4.2 6.9 22.1 6.4 6.3 22.1 1.2 1 0 0 1 1 1 0 Spt20 family FUSC PF04632.12 EKX51188.1 - 8.6 4.8 7.5 12 4.3 5.6 1.8 2 0 0 2 2 2 0 Fusaric acid resistance protein family Menin PF05053.13 EKX51189.1 - 0.8 8.0 15.4 0.95 7.7 15.4 1.0 1 0 0 1 1 1 0 Menin RabGAP-TBC PF00566.18 EKX51191.1 - 9.6e-46 156.1 0.0 1.7e-45 155.3 0.0 1.4 1 1 0 1 1 1 1 Rab-GTPase-TBC domain MIB_HERC2 PF06701.13 EKX51191.1 - 0.00064 19.9 0.1 0.0012 19.0 0.1 1.4 1 0 0 1 1 1 1 Mib_herc2 YchF-GTPase_C PF06071.13 EKX51192.1 - 2.7e-40 136.4 0.1 9.1e-39 131.5 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EKX51192.1 - 1.1e-20 73.8 0.0 2.1e-20 72.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EKX51192.1 - 3.9e-06 26.5 0.0 8.3e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B CLP1_P PF16575.5 EKX51192.1 - 0.022 14.6 0.0 0.24 11.2 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop PH PF00169.29 EKX51194.1 - 2.8e-20 72.8 4.3 5.8e-13 49.3 0.3 3.0 3 0 0 3 3 3 2 PH domain TPR_8 PF13181.6 EKX51194.1 - 1.4e-10 40.5 0.2 0.007 16.5 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX51194.1 - 4.9e-10 38.7 0.1 0.0016 18.4 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX51194.1 - 4.5e-09 35.8 0.0 0.019 14.8 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX51194.1 - 7.4e-09 35.8 5.9 0.00044 20.5 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX51194.1 - 2.2e-07 31.1 0.1 0.02 15.7 0.0 4.0 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX51194.1 - 8.9e-06 25.7 0.1 0.54 10.8 0.0 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX51194.1 - 1.2e-05 25.0 3.1 0.099 12.5 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX51194.1 - 1.6e-05 24.5 1.0 0.038 14.0 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat PH_8 PF15409.6 EKX51194.1 - 9e-05 22.7 0.2 0.097 13.0 0.0 2.7 2 0 0 2 2 2 2 Pleckstrin homology domain TPR_11 PF13414.6 EKX51194.1 - 0.00012 21.7 0.0 0.00044 19.9 0.0 2.1 2 0 0 2 2 1 1 TPR repeat PH_16 PF17838.1 EKX51194.1 - 0.00065 19.5 0.0 0.19 11.5 0.0 3.2 3 0 0 3 3 3 1 PH domain TPR_9 PF13371.6 EKX51194.1 - 0.003 17.7 0.2 0.52 10.5 0.0 3.2 2 2 1 3 3 3 2 Tetratricopeptide repeat PH_11 PF15413.6 EKX51194.1 - 0.013 15.9 9.3 0.15 12.5 2.5 3.8 2 2 0 2 2 2 0 Pleckstrin homology domain TPR_19 PF14559.6 EKX51194.1 - 0.024 15.1 0.1 0.77 10.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EKX51194.1 - 0.026 15.1 0.1 0.13 13.0 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat SCRL PF06876.12 EKX51194.1 - 0.14 12.4 2.3 16 5.8 0.2 2.8 2 0 0 2 2 2 0 Plant self-incompatibility response (SCRL) protein Glyco_hydro_35 PF01301.19 EKX51195.1 - 6.3e-76 256.0 3.7 4.6e-74 249.9 3.7 2.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 EKX51195.1 - 5.3e-06 26.0 0.7 0.00021 20.7 0.7 2.1 1 1 1 2 2 2 2 Beta-galactosidase BetaGal_dom4_5 PF13364.6 EKX51195.1 - 0.00092 19.8 0.0 0.0029 18.2 0.0 1.8 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Cellulase PF00150.18 EKX51195.1 - 0.027 13.9 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) PseudoU_synth_1 PF01416.20 EKX51196.1 - 4.1e-10 40.1 0.0 1.6e-07 31.7 0.0 3.4 3 0 0 3 3 3 2 tRNA pseudouridine synthase PDZ_6 PF17820.1 EKX51197.1 - 9e-09 35.0 0.1 1.8e-08 34.1 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX51197.1 - 0.0023 18.2 0.0 0.0039 17.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX51197.1 - 0.053 13.5 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 Tricorn protease PDZ domain PDZ PF00595.24 EKX51197.1 - 0.15 12.5 0.1 0.43 11.0 0.0 1.9 2 0 0 2 2 2 0 PDZ domain Cyt-b5 PF00173.28 EKX51199.1 - 4.4e-21 74.8 3.5 1.3e-20 73.3 0.1 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 EKX51199.1 - 1.2e-13 51.6 16.0 1.2e-13 51.6 16.0 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 EKX51199.1 - 0.015 15.5 0.1 0.026 14.7 0.1 1.3 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region DCD PF06559.11 EKX51200.1 - 5.2e-58 196.6 0.0 2e-57 194.6 0.0 1.7 1 1 0 1 1 1 1 2'-deoxycytidine 5'-triphosphate deaminase (DCD) ESR1_C PF12743.7 EKX51203.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal Cdc13_OB2 PF18691.1 EKX51203.1 - 0.12 12.4 1.1 0.83 9.7 0.2 2.2 1 1 0 2 2 2 0 Cell division control protein 13, OB2 domain UPF0449 PF15136.6 EKX51203.1 - 0.33 11.5 2.2 10 6.7 0.1 2.8 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 Ank_2 PF12796.7 EKX51205.1 - 2e-14 53.9 0.2 7.6e-08 32.8 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX51205.1 - 7.3e-14 51.9 0.2 1.8e-07 31.6 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX51205.1 - 2.6e-13 49.8 1.6 0.00025 21.3 0.2 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EKX51205.1 - 7.9e-13 48.4 0.9 0.00014 22.1 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX51205.1 - 1.8e-09 37.0 0.4 0.022 15.3 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EKX51206.1 - 3.9e-18 65.6 0.2 1.2e-07 32.1 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX51206.1 - 7.2e-15 54.9 0.9 1.8e-11 44.0 0.2 2.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX51206.1 - 5.5e-14 52.5 0.2 3.7e-13 49.9 0.2 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX51206.1 - 4.9e-12 45.7 2.0 4.8e-07 29.9 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EKX51206.1 - 5.4e-09 35.6 0.5 0.0003 21.0 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat RRM_1 PF00076.22 EKX51207.1 - 7.6e-28 96.1 0.2 3.4e-16 58.8 0.1 3.9 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EKX51207.1 - 0.0031 17.6 0.1 0.062 13.4 0.0 2.9 2 1 0 2 2 2 1 RNA recognition motif Baculo_11_kDa PF06143.11 EKX51207.1 - 0.074 12.6 0.1 0.24 11.0 0.1 1.9 1 0 0 1 1 1 0 Baculovirus 11 kDa family Presenilin PF01080.17 EKX51207.1 - 5 5.8 24.2 0.95 8.2 4.9 2.4 2 0 0 2 2 2 0 Presenilin PaO PF08417.12 EKX51208.1 - 2.1e-19 69.4 0.0 4.6e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Pheophorbide a oxygenase Rieske PF00355.26 EKX51208.1 - 3.6e-18 65.3 0.0 7.4e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain MPP6 PF10175.9 EKX51210.1 - 4.6e-09 36.9 5.3 3.3e-07 30.9 5.3 2.4 1 1 0 1 1 1 1 M-phase phosphoprotein 6 zf-CCCH_3 PF15663.5 EKX51210.1 - 0.073 13.3 0.3 4.6 7.5 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger containing family ssDNA_TraI_N PF18272.1 EKX51210.1 - 0.091 12.8 0.7 17 5.5 0.6 2.5 2 0 0 2 2 2 0 single-stranded DNA binding TraI N-terminal subdomain SPRY PF00622.28 EKX51211.1 - 1.7e-08 34.6 0.0 4e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 SPRY domain HisG PF01634.18 EKX51212.1 - 5.3e-52 176.0 0.5 7.6e-52 175.5 0.5 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 EKX51212.1 - 1.3e-26 92.5 0.0 2.3e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 EKX51212.1 - 0.00051 20.0 0.5 0.00072 19.6 0.5 1.3 1 0 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.20 EKX51212.1 - 0.0071 15.8 0.0 0.013 14.9 0.0 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Ribosomal_L12 PF00542.19 EKX51212.1 - 0.046 14.1 1.5 4.7 7.6 0.1 3.0 2 1 1 3 3 3 0 Ribosomal protein L7/L12 C-terminal domain ArfGap PF01412.18 EKX51213.1 - 1.5e-09 38.0 0.3 1.5e-09 37.9 0.3 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-B_box PF00643.24 EKX51213.1 - 0.0071 16.5 1.6 0.0091 16.1 1.6 1.2 1 0 0 1 1 1 1 B-box zinc finger Alk_phosphatase PF00245.20 EKX51214.1 - 4e-38 131.5 1.7 1.5e-19 70.2 0.2 2.7 2 1 0 2 2 2 2 Alkaline phosphatase Iso_dh PF00180.20 EKX51214.1 - 0.013 14.7 0.0 0.024 13.8 0.0 1.4 1 0 0 1 1 1 0 Isocitrate/isopropylmalate dehydrogenase Ribonuc_red_sm PF00268.21 EKX51216.1 - 2.2e-120 401.3 1.2 2.6e-120 401.1 1.2 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Flp_C PF05202.12 EKX51216.1 - 0.024 14.2 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Recombinase Flp protein C6_DPF PF10170.9 EKX51216.1 - 0.04 14.3 0.0 0.093 13.1 0.0 1.6 1 0 0 1 1 1 0 Cysteine-rich domain NMT PF01233.19 EKX51216.1 - 0.045 13.6 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Glyco_transf_15 PF01793.16 EKX51217.1 - 0.0054 16.0 0.1 0.0066 15.7 0.1 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PDZ_6 PF17820.1 EKX51218.1 - 3.4e-16 58.8 0.1 8.3e-06 25.6 0.0 3.7 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.24 EKX51218.1 - 1.9e-15 56.9 1.0 9e-06 26.0 0.4 3.4 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 EKX51218.1 - 7e-14 51.9 0.3 0.00049 20.4 0.0 3.7 3 0 0 3 3 3 3 PDZ domain Tricorn_PDZ PF14685.6 EKX51218.1 - 0.0013 18.7 0.0 6 6.9 0.0 3.7 3 0 0 3 3 3 2 Tricorn protease PDZ domain Usp PF00582.26 EKX51218.1 - 6.1 7.4 9.2 1.9 9.0 1.0 3.3 4 0 0 4 4 4 0 Universal stress protein family Glyco_transf_54 PF04666.13 EKX51219.1 - 0.15 10.9 0.5 1.7 7.5 0.2 2.1 2 0 0 2 2 2 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Dus PF01207.17 EKX51220.1 - 4.5e-64 216.5 0.0 5.8e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EKX51220.1 - 0.0034 16.9 0.0 0.017 14.6 0.0 1.9 2 0 0 2 2 2 1 Histidine biosynthesis protein S36_mt PF10937.8 EKX51221.1 - 0.088 14.4 0.6 0.088 14.4 0.6 1.6 2 0 0 2 2 2 0 Ribosomal protein S36, mitochondrial EPTP PF03736.17 EKX51223.1 - 1.6e-44 149.6 31.6 6.5e-06 26.0 0.1 12.9 13 0 0 13 13 13 11 EPTP domain Kelch_6 PF13964.6 EKX51223.1 - 1.6e-05 25.0 0.4 0.016 15.5 0.0 4.6 4 0 0 4 4 4 1 Kelch motif Glyco_hydro2_C5 PF18565.1 EKX51223.1 - 0.036 13.9 2.7 9.2 6.2 0.0 5.7 5 0 0 5 5 5 0 Glycoside hydrolase family 2 C-terminal domain 5 CarboxypepD_reg PF13620.6 EKX51223.1 - 0.046 14.0 14.7 1.8 8.9 0.0 6.1 6 0 0 6 6 6 0 Carboxypeptidase regulatory-like domain Kelch_3 PF13415.6 EKX51223.1 - 0.05 13.9 0.4 3.9 7.9 0.0 3.6 3 0 0 3 3 3 0 Galactose oxidase, central domain HA PF03457.14 EKX51224.1 - 2.3e-61 204.0 5.7 2.9e-16 59.5 0.4 4.7 4 1 0 4 4 4 4 Helicase associated domain Ank_4 PF13637.6 EKX51226.1 - 3.1e-09 37.2 2.1 1.3e-07 32.0 0.4 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX51226.1 - 9.5e-09 35.4 1.9 4.7e-06 26.8 0.4 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX51226.1 - 2e-08 34.3 0.4 1.2e-05 25.5 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EKX51226.1 - 3.5e-08 33.9 0.1 7.2e-08 32.9 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX51226.1 - 2.1e-07 30.7 0.1 0.00015 21.9 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat SNF2_N PF00176.23 EKX51227.1 - 3.3e-66 223.4 0.1 3.3e-66 223.4 0.1 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX51227.1 - 2.3e-20 73.0 0.0 1.9e-19 70.0 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX51227.1 - 5.7e-11 42.7 0.0 5.7e-11 42.7 0.0 3.1 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit SnAC PF14619.6 EKX51227.1 - 4.5e-05 24.0 7.4 4.5e-05 24.0 7.4 3.1 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.13 EKX51227.1 - 0.0012 19.2 14.5 0.0012 19.2 14.5 2.7 3 0 0 3 3 3 1 HSA FHA PF00498.26 EKX51228.1 - 2.3e-14 53.5 0.1 3.3e-14 53.0 0.1 1.2 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EKX51228.1 - 9.9e-14 51.4 0.0 1.3e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain RWP-RK PF02042.15 EKX51231.1 - 1.7e-13 50.3 0.0 3.2e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX51232.1 - 1.2e-13 50.8 0.0 2.4e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX51233.1 - 1.7e-13 50.3 0.0 3.2e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain Ribosomal_L32e PF01655.18 EKX51234.1 - 1.3e-45 154.3 0.8 1.6e-45 153.9 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Pribosyltran PF00156.27 EKX51235.1 - 4.8e-19 68.4 0.0 7.2e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EKX51235.1 - 5.8e-05 22.6 0.0 8.2e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 EKX51235.1 - 0.21 11.1 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase ATP12 PF07542.11 EKX51237.1 - 1.9e-19 70.0 0.1 1.5e-18 67.1 0.0 2.2 2 1 0 2 2 2 1 ATP12 chaperone protein Abhydrolase_6 PF12697.7 EKX51238.1 - 1.3e-20 74.9 0.1 2e-20 74.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EKX51238.1 - 3e-13 50.0 0.2 5.1e-10 39.4 0.3 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EKX51238.1 - 2.3e-12 46.7 0.0 3e-09 36.5 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 EKX51238.1 - 0.00013 21.9 0.0 0.67 9.8 0.0 2.5 2 1 0 2 2 2 2 Serine hydrolase DUF2920 PF11144.8 EKX51238.1 - 0.062 12.5 0.2 0.71 9.0 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) FSH1 PF03959.13 EKX51238.1 - 0.13 11.9 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) GDP_Man_Dehyd PF16363.5 EKX51239.1 - 4.8e-148 493.0 0.0 5.4e-148 492.8 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EKX51239.1 - 1e-70 237.9 0.1 1.2e-70 237.7 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EKX51239.1 - 1.5e-05 24.3 0.0 2.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EKX51239.1 - 6.6e-05 22.1 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 EKX51239.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Tau95 PF09734.9 EKX51241.1 - 0.014 16.2 1.4 0.014 16.2 1.4 1.6 1 1 1 2 2 2 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain DUF573 PF04504.14 EKX51241.1 - 0.025 15.2 3.5 0.036 14.7 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF573 Tox-ODYAM1 PF15642.6 EKX51241.1 - 0.054 12.5 4.8 0.061 12.3 4.8 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Mannitol_dh PF01232.23 EKX51241.1 - 0.069 13.3 0.9 0.1 12.7 0.9 1.3 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain DUF4795 PF16043.5 EKX51241.1 - 0.073 12.7 8.6 0.1 12.2 8.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) FapA PF03961.13 EKX51241.1 - 0.11 11.1 5.3 0.13 10.8 5.3 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMPIT PF07851.13 EKX51241.1 - 0.14 11.4 6.1 0.18 11.0 6.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein Spc7 PF08317.11 EKX51241.1 - 0.23 10.3 12.3 0.26 10.1 12.3 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Fez1 PF06818.15 EKX51241.1 - 0.25 11.8 12.7 0.12 12.8 9.0 1.8 1 1 1 2 2 2 0 Fez1 HIP1_clath_bdg PF16515.5 EKX51241.1 - 0.73 10.5 16.4 2.1 9.0 14.4 2.2 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CorA PF01544.18 EKX51241.1 - 0.93 8.7 9.7 1.4 8.1 9.7 1.3 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Exonuc_VII_L PF02601.15 EKX51241.1 - 0.97 8.9 8.7 1.2 8.6 8.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4355 PF14265.6 EKX51241.1 - 0.97 9.7 8.6 1.7 8.9 8.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DUF1451 PF07295.11 EKX51241.1 - 1.4 9.0 9.4 0.71 9.9 7.2 1.7 2 0 0 2 2 2 0 Zinc-ribbon containing domain eIF-4B PF06273.11 EKX51241.1 - 5.4 5.9 8.3 7.2 5.5 8.3 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B PPR_2 PF13041.6 EKX51242.1 - 4.2e-21 74.9 0.0 1.4e-08 34.8 0.0 4.5 2 1 3 5 5 5 4 PPR repeat family PPR PF01535.20 EKX51242.1 - 7.8e-19 66.5 0.8 6.7e-05 22.9 0.0 6.1 6 0 0 6 6 6 3 PPR repeat Methyltransf_4 PF02390.17 EKX51242.1 - 3.8e-18 65.5 3.3 9.5e-18 64.3 0.0 2.7 2 0 0 2 2 2 1 Putative methyltransferase PPR_1 PF12854.7 EKX51242.1 - 5.2e-14 51.6 0.1 2.9e-06 26.9 0.1 4.5 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.6 EKX51242.1 - 2.6e-09 37.0 0.0 0.0012 18.9 0.0 3.1 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_long PF17177.4 EKX51242.1 - 0.0057 16.0 0.1 0.016 14.6 0.1 1.8 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP DUF4816 PF16086.5 EKX51242.1 - 9 6.3 14.5 14 5.7 12.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4816) WD40 PF00400.32 EKX51243.1 - 9.3e-11 42.1 4.7 0.012 16.5 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF1802 PF08819.11 EKX51244.1 - 0.014 15.3 0.1 0.019 14.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1802) Pex14_N PF04695.13 EKX51244.1 - 0.055 14.1 0.4 0.074 13.7 0.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ZT_dimer PF16916.5 EKX51245.1 - 0.061 13.5 0.1 0.27 11.4 0.0 2.1 2 0 0 2 2 2 0 Dimerisation domain of Zinc Transporter Glyco_hydro_9 PF00759.19 EKX51245.1 - 0.11 11.9 6.5 0.13 11.7 6.5 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Sulfatase_C PF14707.6 EKX51245.1 - 1.5 9.6 8.2 2.4 8.9 1.2 2.7 1 1 1 3 3 3 0 C-terminal region of aryl-sulfatase OmpH PF03938.14 EKX51245.1 - 1.8 8.9 18.4 1 9.7 7.5 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Spc7 PF08317.11 EKX51245.1 - 2.8 6.7 20.5 2.8 6.7 1.9 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein RasGAP_C PF03836.15 EKX51245.1 - 4 7.6 10.9 0.79 9.9 4.8 2.2 1 1 0 2 2 2 0 RasGAP C-terminus DUF3584 PF12128.8 EKX51245.1 - 4.5 4.6 24.0 5.7 4.3 24.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF948 PF06103.11 EKX51245.1 - 7 7.0 7.4 1.1 9.5 0.1 2.7 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Peptidase_S64 PF08192.11 EKX51245.1 - 7.2 5.0 14.8 9 4.7 14.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 DUF2203 PF09969.9 EKX51245.1 - 7.4 7.3 17.8 1.7 9.4 6.1 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) LCIB_C_CA PF18599.1 EKX51245.1 - 9.6 5.4 6.6 15 4.8 0.4 2.3 1 1 1 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases PX PF00787.24 EKX51246.1 - 7.8e-26 90.3 0.3 2.1e-25 88.9 0.3 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 EKX51246.1 - 2.4e-16 60.0 5.4 2.1e-15 57.0 5.4 1.9 1 1 0 1 1 1 1 Vps5 C terminal like Aminotran_1_2 PF00155.21 EKX51247.1 - 1.8e-38 132.6 0.0 2.3e-38 132.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EKX51247.1 - 0.0015 17.9 0.0 0.0033 16.7 0.0 1.6 1 0 0 1 1 1 1 Beta-eliminating lyase FTO_NTD PF12933.7 EKX51248.1 - 4.6e-65 219.7 0.0 1.2e-64 218.4 0.0 1.6 1 1 0 1 1 1 1 FTO catalytic domain FTO_CTD PF12934.7 EKX51248.1 - 8.2e-10 38.7 6.8 2e-08 34.2 6.8 2.4 1 1 0 1 1 1 1 FTO C-terminal domain V-SNARE PF05008.15 EKX51248.1 - 0.36 11.2 1.9 1 9.8 0.1 2.3 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Abhydrolase_3 PF07859.13 EKX51250.1 - 1.6e-42 145.8 1.5 5.1e-40 137.6 0.2 3.2 3 1 0 3 3 3 1 alpha/beta hydrolase fold HSL_N PF06350.12 EKX51250.1 - 3.4e-42 144.5 0.1 5.8e-42 143.7 0.1 1.3 1 0 0 1 1 1 1 Hormone-sensitive lipase (HSL) N-terminus PA PF02225.22 EKX51250.1 - 6.5e-08 32.5 0.0 1.3e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 PA domain Say1_Mug180 PF10340.9 EKX51250.1 - 6e-06 25.4 0.0 1.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase CAP_N PF01213.19 EKX51250.1 - 2.3 7.6 5.1 4.4 6.7 5.1 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RCC_reductase PF06405.11 EKX51251.1 - 9.1e-08 31.6 0.0 1.5e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Red chlorophyll catabolite reductase (RCC reductase) Glyco_transf_6 PF03414.13 EKX51252.1 - 5.5e-12 45.1 0.3 5.8e-08 31.9 0.1 2.9 2 1 0 2 2 2 2 Glycosyltransferase family 6 DUF1700 PF08006.11 EKX51252.1 - 0.0084 15.7 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1700) Pom PF17251.2 EKX51252.1 - 0.057 12.7 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 Protochlamydia outer membrane protein KASH PF10541.9 EKX51252.1 - 2.7 8.3 10.2 1.8 8.9 7.2 2.3 2 0 0 2 2 2 0 Nuclear envelope localisation domain MORN PF02493.20 EKX51255.1 - 5.5e-35 117.2 39.2 1.3e-07 31.1 1.2 6.3 6 0 0 6 6 6 6 MORN repeat HCV_NS5a_1a PF08300.13 EKX51255.1 - 1.3 9.2 7.4 2.3 8.4 0.9 3.5 2 1 1 3 3 3 0 Hepatitis C virus non-structural 5a zinc finger domain zf-RING_2 PF13639.6 EKX51256.1 - 2.5e-11 43.7 12.7 3.7e-11 43.2 12.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EKX51256.1 - 9.6e-09 34.8 5.5 2e-08 33.8 5.5 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EKX51256.1 - 9.6e-07 28.6 8.1 9.6e-07 28.6 8.1 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX51256.1 - 4.2e-06 26.6 10.0 6.2e-06 26.1 10.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EKX51256.1 - 9.9e-06 25.8 15.3 4.5e-05 23.7 15.3 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EKX51256.1 - 1.2e-05 25.0 11.4 1.2e-05 25.0 11.4 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EKX51256.1 - 0.00051 19.8 11.5 0.00073 19.3 11.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX51256.1 - 0.0079 16.2 9.4 0.0079 16.2 9.4 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EKX51256.1 - 0.037 14.1 8.7 0.075 13.1 8.7 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_RING PF05883.11 EKX51256.1 - 0.12 12.3 3.0 0.21 11.6 3.0 1.4 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain RINGv PF12906.7 EKX51256.1 - 0.21 11.7 10.9 0.47 10.6 10.8 1.6 1 1 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 EKX51256.1 - 0.23 11.1 10.3 0.38 10.4 10.3 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EKX51256.1 - 8.9 6.6 13.2 4.6e+02 1.1 13.2 2.8 1 1 0 1 1 1 0 FANCL C-terminal domain TRAF_BIRC3_bd PF16673.5 EKX51257.1 - 1.8e-05 24.4 6.0 1.8e-05 24.4 6.0 2.5 2 0 0 2 2 2 1 TNF receptor-associated factor BIRC3 binding domain Cep57_CLD_2 PF14197.6 EKX51257.1 - 0.044 13.9 0.5 0.044 13.9 0.5 3.6 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Atg14 PF10186.9 EKX51257.1 - 0.11 11.5 19.2 0.029 13.5 13.0 2.5 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 HigB_toxin PF09907.9 EKX51257.1 - 0.11 12.7 0.2 0.27 11.5 0.2 1.6 1 0 0 1 1 1 0 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system Uso1_p115_C PF04871.13 EKX51257.1 - 0.16 12.3 23.2 0.33 11.3 9.5 3.1 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Herpes_IE2_3 PF03361.14 EKX51257.1 - 0.18 11.7 2.1 0.48 10.3 2.1 1.7 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 PDZ_3 PF17815.1 EKX51257.1 - 0.35 10.7 4.1 0.72 9.7 4.1 1.7 1 1 0 1 1 1 0 PDZ domain HALZ PF02183.18 EKX51257.1 - 0.48 10.7 8.8 0.22 11.8 1.7 2.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF4795 PF16043.5 EKX51257.1 - 0.63 9.6 28.9 0.39 10.3 1.3 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) ISG65-75 PF11727.8 EKX51257.1 - 1.7 7.8 10.8 0.22 10.7 5.6 2.0 1 1 0 2 2 2 0 Invariant surface glycoprotein GAS PF13851.6 EKX51257.1 - 5.1 6.4 30.4 75 2.6 1.5 3.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FOXP-CC PF16159.5 EKX51257.1 - 6.2 7.5 10.9 11 6.7 0.3 3.4 3 0 0 3 3 3 0 FOXP coiled-coil domain DUF2400 PF09674.10 EKX51257.1 - 6.6 6.7 7.5 11 6.0 6.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2400) EF-hand_6 PF13405.6 EKX51258.1 - 0.00057 19.6 0.3 0.0017 18.1 0.3 1.8 1 0 0 1 1 1 1 EF-hand domain HeLo PF14479.6 EKX51258.1 - 0.0082 16.0 5.3 0.012 15.5 0.9 2.3 2 0 0 2 2 2 1 Prion-inhibition and propagation EF-hand_1 PF00036.32 EKX51258.1 - 0.052 13.1 0.0 0.052 13.1 0.0 2.0 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 EKX51258.1 - 0.56 10.7 5.8 0.21 12.1 0.4 2.5 2 0 0 2 2 2 0 EF-hand domain pair DUF3458_C PF17432.2 EKX51260.1 - 5.8e-105 351.2 9.3 9.3e-105 350.5 9.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 EKX51260.1 - 6.8e-53 179.5 0.3 1.1e-52 178.8 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 EKX51260.1 - 1.8e-25 89.2 0.0 3.8e-25 88.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 EKX51260.1 - 3.8e-15 56.6 0.0 6.9e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M61 PF05299.12 EKX51260.1 - 0.022 15.1 0.0 0.071 13.5 0.0 2.0 1 0 0 1 1 1 0 M61 glycyl aminopeptidase DUF2268 PF10026.9 EKX51260.1 - 0.053 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) AICARFT_IMPCHas PF01808.18 EKX51261.1 - 2e-78 263.9 0.1 2.7e-78 263.4 0.1 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EKX51261.1 - 1.8e-25 89.0 0.0 3.6e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain Retrotrans_gag PF03732.17 EKX51262.1 - 0.0026 18.0 3.5 0.68 10.2 0.2 3.1 2 0 0 2 2 2 2 Retrotransposon gag protein RRM_1 PF00076.22 EKX51262.1 - 0.0098 15.7 0.0 0.11 12.3 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EKX51262.1 - 0.02 15.0 0.1 0.2 11.8 0.0 2.6 2 0 0 2 2 2 0 Limkain b1 Snapin_Pallidin PF14712.6 EKX51262.1 - 8.8 6.8 21.9 3.7 8.0 5.3 4.7 5 0 0 5 5 5 0 Snapin/Pallidin Ank_4 PF13637.6 EKX51263.1 - 2.1e-21 76.0 0.0 1.8e-10 41.1 0.0 3.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX51263.1 - 8.2e-21 74.4 0.2 8.5e-11 42.3 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EKX51263.1 - 2.3e-16 59.4 0.2 0.00064 20.0 0.3 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EKX51263.1 - 2.1e-15 55.3 0.1 0.00015 21.9 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EKX51263.1 - 2.4e-13 50.0 0.6 1.3e-05 25.4 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) RMI1_N PF08585.12 EKX51265.1 - 1.4e-24 87.1 0.9 2.6e-18 66.6 0.3 2.3 1 1 1 2 2 2 2 RecQ mediated genome instability protein DUF1090 PF06476.12 EKX51266.1 - 0.00033 20.8 57.2 0.23 11.6 1.3 8.2 1 1 8 9 9 9 8 Protein of unknown function (DUF1090) AAA_22 PF13401.6 EKX51266.1 - 0.0069 16.7 0.3 0.041 14.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain RMI1_N PF08585.12 EKX51267.1 - 9e-20 71.4 1.0 1.9e-19 70.3 0.2 1.6 1 1 1 2 2 2 1 RecQ mediated genome instability protein Sarcolipin PF05366.11 EKX51268.1 - 1.5 8.5 3.8 0.66 9.7 1.1 1.8 2 0 0 2 2 2 0 Sarcolipin Bap31_Bap29_C PF18035.1 EKX51268.1 - 9.6 6.3 7.6 26 4.9 0.4 2.3 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain PGDH_C PF16896.5 EKX51269.1 - 0.084 12.8 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Phosphogluconate dehydrogenase (decarboxylating) C-term Il13Ra_Ig PF18001.1 EKX51270.1 - 0.023 14.8 1.1 0.028 14.5 1.1 1.1 1 0 0 1 1 1 0 Interleukin-13 receptor subunit alpha Ig-like domain HAD_2 PF13419.6 EKX51271.1 - 1.1e-08 35.4 0.0 3e-08 34.0 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase NT5C PF06941.12 EKX51271.1 - 0.011 15.6 0.0 2.6 7.9 0.0 2.1 1 1 1 2 2 2 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Hydrolase PF00702.26 EKX51271.1 - 0.015 15.6 0.0 0.17 12.1 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Aminotran_1_2 PF00155.21 EKX51272.1 - 1e-40 140.0 0.0 1.2e-40 139.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EKX51272.1 - 0.0011 18.1 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EKX51272.1 - 0.0014 17.2 0.0 0.0019 16.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.13 EKX51272.1 - 0.0033 16.3 0.0 0.0044 15.9 0.0 1.1 1 0 0 1 1 1 1 Allinase XRN_N PF03159.18 EKX51273.1 - 2e-92 309.0 0.0 2.3e-92 308.8 0.0 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus CotJA PF11007.8 EKX51273.1 - 0.062 13.1 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Spore coat associated protein JA (CotJA) Rdx PF10262.9 EKX51274.1 - 0.0046 17.1 0.0 0.016 15.4 0.0 1.9 1 1 0 1 1 1 1 Rdx family CarboxypepD_reg PF13620.6 EKX51274.1 - 0.022 15.0 0.0 2.4 8.5 0.0 2.4 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 EKX51274.1 - 0.064 13.3 0.0 5.7 7.0 0.0 2.4 2 0 0 2 2 2 0 CarboxypepD_reg-like domain Ints3 PF10189.9 EKX51275.1 - 1.4e-76 256.7 0.0 2.3e-76 256.0 0.0 1.3 1 0 0 1 1 1 1 Integrator complex subunit 3 UPF0004 PF00919.20 EKX51277.1 - 8.9e-28 96.2 0.1 4.7e-27 93.9 0.2 2.1 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 EKX51277.1 - 1e-24 87.8 0.1 2.5e-24 86.5 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily TRAM_2 PF18693.1 EKX51277.1 - 3.8e-13 49.4 3.4 1.5e-12 47.5 1.2 2.5 2 0 0 2 2 2 1 TRAM domain Fer4_12 PF13353.6 EKX51277.1 - 0.18 12.1 0.1 1 9.7 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S single cluster domain NAGidase PF07555.13 EKX51277.1 - 0.22 10.8 0.0 0.43 9.9 0.0 1.4 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase Pacs-1 PF10254.9 EKX51279.1 - 1.8e-14 53.5 0.0 7e-07 28.5 0.0 3.2 1 1 1 2 2 2 2 PACS-1 cytosolic sorting protein AAA_11 PF13086.6 EKX51280.1 - 0.083 12.7 0.4 0.1 12.4 0.4 1.2 1 0 0 1 1 1 0 AAA domain DUF3666 PF12408.8 EKX51280.1 - 0.17 11.1 0.1 0.32 10.2 0.1 1.4 1 0 0 1 1 1 0 Ribose-5-phosphate isomerase Vac_Fusion PF02346.16 EKX51280.1 - 0.86 9.3 3.6 0.78 9.4 1.3 2.0 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 Pox_A_type_inc PF04508.12 EKX51281.1 - 0.025 14.4 1.6 0.089 12.7 1.6 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Mpp10 PF04006.12 EKX51281.1 - 0.67 8.3 4.9 0.069 11.6 0.7 1.4 2 0 0 2 2 2 0 Mpp10 protein Metallophos PF00149.28 EKX51282.1 - 9.8e-22 78.4 1.1 1.4e-21 78.0 1.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PhoD PF09423.10 EKX51282.1 - 0.0014 17.7 0.0 0.81 8.6 0.0 2.1 2 0 0 2 2 2 2 PhoD-like phosphatase Metallophos_2 PF12850.7 EKX51282.1 - 0.077 13.2 0.1 0.76 9.9 0.1 2.0 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain NPV_P10 PF05531.12 EKX51283.1 - 0.00083 19.8 6.1 0.021 15.3 0.1 4.0 2 2 2 4 4 4 1 Nucleopolyhedrovirus P10 protein GBP_C PF02841.14 EKX51283.1 - 0.0091 15.4 2.5 0.0091 15.4 2.5 2.9 2 1 2 4 4 4 1 Guanylate-binding protein, C-terminal domain Snapin_Pallidin PF14712.6 EKX51283.1 - 0.031 14.7 11.3 6.5 7.2 0.2 4.8 3 1 0 4 4 4 0 Snapin/Pallidin AAA_lid_9 PF17871.1 EKX51283.1 - 0.12 12.3 0.1 0.12 12.3 0.1 3.6 2 1 1 3 3 3 0 AAA lid domain DUF4665 PF15679.5 EKX51283.1 - 1.1 9.9 7.4 3.9 8.2 0.5 3.5 2 2 1 3 3 3 0 Domain of unknown function (DUF4665) FtsQ PF03799.15 EKX51283.1 - 1.5 9.6 7.1 5.2 7.9 0.2 3.5 3 1 0 3 3 3 0 Cell division protein FtsQ DUF16 PF01519.16 EKX51283.1 - 2.5 8.6 10.2 0.5 10.9 0.4 3.3 2 1 0 2 2 2 0 Protein of unknown function DUF16 Baculo_PEP_C PF04513.12 EKX51283.1 - 7.5 6.6 8.8 1.2e+02 2.7 5.8 3.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Occludin_ELL PF07303.13 EKX51283.1 - 10 6.9 18.9 27 5.6 0.3 5.0 2 1 4 6 6 6 0 Occludin homology domain Arm PF00514.23 EKX51284.1 - 0.046 13.8 0.1 0.44 10.7 0.0 2.4 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat OTU PF02338.19 EKX51285.1 - 1e-07 32.5 0.1 1.5e-07 31.9 0.1 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease hSac2 PF12456.8 EKX51286.1 - 5.4e-09 35.8 0.0 7.2e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Inositol phosphatase NOP19 PF10863.8 EKX51287.1 - 0.05 13.4 2.8 0.18 11.7 2.9 2.0 1 1 1 2 2 2 0 Nucleolar protein 19 DUF3818 PF12825.7 EKX51287.1 - 0.93 8.5 5.0 0.34 9.9 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) BACK PF07707.15 EKX51288.1 - 1.7e-09 37.7 0.1 2e-08 34.3 0.1 2.3 1 1 0 1 1 1 1 BTB And C-terminal Kelch EGF_2 PF07974.13 EKX51289.1 - 0.019 15.3 10.7 0.048 14.0 10.7 1.7 1 0 0 1 1 1 0 EGF-like domain Coatomer_E PF04733.14 EKX51290.1 - 2.4e-98 329.1 1.5 2.7e-98 329.0 1.5 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_2 PF07719.17 EKX51290.1 - 1.6e-07 30.9 0.6 0.015 15.3 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX51290.1 - 1.8e-07 31.6 5.8 0.0013 19.2 0.2 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX51290.1 - 7e-06 25.6 0.4 0.024 14.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX51290.1 - 1.8e-05 24.4 0.0 0.062 13.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX51290.1 - 2.1e-05 24.9 1.6 1.7 9.7 0.0 4.7 3 1 3 6 6 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX51290.1 - 0.0006 19.8 3.1 0.45 10.9 0.1 3.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX51290.1 - 0.0058 16.9 2.8 0.99 9.7 0.0 4.2 5 1 1 6 6 6 1 Tetratricopeptide repeat SPOB_a PF14689.6 EKX51290.1 - 0.0059 16.3 1.0 2 8.2 0.0 4.1 5 0 0 5 5 5 1 Sensor_kinase_SpoOB-type, alpha-helical domain SRP_TPR_like PF17004.5 EKX51290.1 - 0.0069 16.4 0.3 0.74 9.8 0.0 2.6 1 1 0 2 2 2 1 Putative TPR-like repeat NARP1 PF12569.8 EKX51290.1 - 0.007 15.3 0.5 0.42 9.5 0.1 2.0 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 ANAPC3 PF12895.7 EKX51290.1 - 0.0077 16.4 0.4 1.3 9.3 0.1 3.0 2 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EKX51290.1 - 0.033 14.8 0.1 5.3 7.8 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EKX51290.1 - 0.044 13.5 0.7 4.5 7.1 0.0 3.4 3 0 0 3 3 3 0 TPR repeat TPR_10 PF13374.6 EKX51290.1 - 0.094 12.6 4.3 1.8 8.6 0.0 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EKX51290.1 - 0.73 10.6 2.8 4.6 8.2 0.0 3.3 5 0 0 5 5 3 0 Tetratricopeptide repeat eIF-1a PF01176.19 EKX51291.1 - 9.5e-13 47.8 0.0 1.3e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 GBV-C_env PF12786.7 EKX51291.1 - 0.024 13.4 0.1 0.034 12.9 0.1 1.1 1 0 0 1 1 1 0 GB virus C genotype envelope Mito_carr PF00153.27 EKX51293.1 - 7.3e-56 186.1 1.0 1.8e-20 72.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 EKX51293.1 - 3e-05 24.2 0.0 7.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Pkinase_Tyr PF07714.17 EKX51294.1 - 3.7e-28 98.5 0.8 8.1e-18 64.6 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 EKX51294.1 - 5.2e-09 35.9 0.2 9.3e-05 21.9 0.1 2.1 1 1 1 2 2 2 2 Protein kinase domain UBA PF00627.31 EKX51295.1 - 0.00049 19.9 0.1 0.001 18.9 0.1 1.5 1 1 0 1 1 1 1 UBA/TS-N domain SNF2_N PF00176.23 EKX51296.1 - 9.2e-45 152.9 0.9 1.8e-41 142.1 0.9 2.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX51296.1 - 1.4e-09 38.2 0.0 5.2e-09 36.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 EKX51296.1 - 2e-09 37.7 12.2 5.6e-09 36.2 12.2 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EKX51296.1 - 7.1e-07 29.1 10.1 2.1e-06 27.6 10.1 1.9 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EKX51296.1 - 1.3e-05 25.0 9.7 2.9e-05 23.8 9.7 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EKX51296.1 - 0.00028 20.7 12.4 0.00077 19.3 12.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX51296.1 - 0.0033 17.4 9.4 0.0087 16.1 9.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EKX51296.1 - 0.0057 16.7 3.3 0.015 15.3 3.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 EKX51296.1 - 0.007 16.2 11.2 0.019 14.8 11.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EKX51296.1 - 0.008 15.9 11.5 0.023 14.5 11.5 1.8 1 0 0 1 1 1 1 RING-like zinc finger Rad50_zn_hook PF04423.14 EKX51296.1 - 0.0082 16.0 1.6 0.33 10.8 0.0 2.7 2 0 0 2 2 2 1 Rad50 zinc hook motif FYDLN_acid PF09538.10 EKX51296.1 - 0.019 15.6 1.9 0.019 15.6 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Rtf2 PF04641.12 EKX51296.1 - 0.029 13.7 8.0 0.074 12.4 8.0 1.7 1 0 0 1 1 1 0 Rtf2 RING-finger zf-rbx1 PF12678.7 EKX51296.1 - 0.057 13.7 9.3 0.043 14.1 6.4 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 EKX51296.1 - 0.08 12.7 10.0 0.17 11.7 10.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Toprim_2 PF13155.6 EKX51296.1 - 0.87 10.0 3.3 10 6.7 0.2 3.3 3 1 0 3 3 3 0 Toprim-like zf-C3HC4_4 PF15227.6 EKX51296.1 - 1.6 8.9 12.2 6.2 7.1 12.2 2.1 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1682 PF07946.14 EKX51296.1 - 9.2 5.4 10.8 2.2 7.4 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) RVT_1 PF00078.27 EKX51298.1 - 4.4e-07 29.6 0.0 0.00016 21.3 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DUF5486 PF17588.2 EKX51298.1 - 0.00058 19.7 0.0 1.8 8.5 0.0 2.5 2 0 0 2 2 2 2 Family of unknown function (DUF5486) ORC5_C PF14630.6 EKX51298.1 - 0.038 13.5 2.1 0.056 12.9 0.1 2.1 3 0 0 3 3 3 0 Origin recognition complex (ORC) subunit 5 C-terminus mRNA_cap_enzyme PF01331.19 EKX51299.1 - 0.0057 16.5 0.0 0.0083 16.0 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.21 EKX51299.1 - 0.053 13.1 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 ATP dependent DNA ligase domain HPP PF04982.13 EKX51300.1 - 9e-24 84.0 5.4 4.5e-18 65.6 2.1 2.6 3 0 0 3 3 3 2 HPP family FUSC PF04632.12 EKX51300.1 - 0.0027 16.3 0.1 0.0027 16.3 0.1 1.8 2 0 0 2 2 2 1 Fusaric acid resistance protein family FtsX PF02687.21 EKX51301.1 - 1.2e-15 57.7 47.7 2.3e-10 40.8 4.4 5.5 5 1 0 5 5 5 3 FtsX-like permease family Peptidase_S8 PF00082.22 EKX51302.1 - 7.7e-20 71.3 0.0 5.2e-19 68.6 0.0 2.2 1 1 0 1 1 1 1 Subtilase family HTH_Tnp_Tc5 PF03221.16 EKX51303.1 - 4.4e-08 33.0 0.0 8.7e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 EKX51303.1 - 0.0035 16.9 0.7 0.0035 16.9 0.7 2.0 3 0 0 3 3 3 1 CENP-B N-terminal DNA-binding domain Phage_Cox PF10743.9 EKX51303.1 - 0.05 13.7 0.0 0.27 11.3 0.0 2.0 2 0 0 2 2 2 0 Regulatory phage protein cox DUF3572 PF12096.8 EKX51303.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3572) Neogenin_C PF06583.12 EKX51304.1 - 0.042 13.7 0.3 0.076 12.9 0.3 1.3 1 0 0 1 1 1 0 Neogenin C-terminus LPP PF04728.13 EKX51305.1 - 0.0041 17.5 0.6 0.0041 17.5 0.6 4.3 2 2 2 4 4 4 1 Lipoprotein leucine-zipper DUF812 PF05667.11 EKX51305.1 - 0.051 12.5 51.1 0.065 12.1 51.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ERM PF00769.19 EKX51305.1 - 0.11 12.3 78.5 0.25 11.1 53.5 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family ZnuA PF01297.17 EKX51305.1 - 4 6.8 16.2 0.23 10.8 9.7 2.1 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic HAUS-augmin3 PF14932.6 EKX51305.1 - 6.8 6.2 53.6 3.2 7.3 24.5 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 TauE PF01925.19 EKX51306.1 - 9.6e-17 61.4 13.1 7.4e-16 58.5 13.1 1.9 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE DUF3413 PF11893.8 EKX51306.1 - 0.013 14.7 0.5 0.021 14.0 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) P_C10 PF14974.6 EKX51307.1 - 2.5e-22 78.9 0.2 2.9e-22 78.7 0.2 1.0 1 0 0 1 1 1 1 Protein C10 IBR PF01485.21 EKX51308.1 - 0.025 14.8 0.5 0.025 14.8 0.5 4.0 3 1 0 3 3 3 0 IBR domain, a half RING-finger domain TPR_12 PF13424.6 EKX51309.1 - 8.3e-28 96.5 30.2 1.3e-08 35.0 1.3 4.4 1 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 EKX51309.1 - 1.4e-11 43.9 12.9 0.014 15.3 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX51309.1 - 5.7e-11 41.7 13.4 0.0039 17.2 0.1 7.3 7 2 0 7 7 7 3 Tetratricopeptide repeat ANAPC5 PF12862.7 EKX51309.1 - 2.3e-09 37.2 0.2 0.0069 16.4 0.0 4.3 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 5 TPR_7 PF13176.6 EKX51309.1 - 6.1e-08 32.2 14.1 0.2 11.8 0.1 6.9 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX51309.1 - 2.4e-07 30.4 4.9 0.22 11.8 0.0 6.3 6 1 2 8 8 8 2 Tetratricopeptide repeat SNAP PF14938.6 EKX51309.1 - 1.4e-06 28.0 0.2 0.00048 19.6 0.1 2.2 2 0 0 2 2 2 2 Soluble NSF attachment protein, SNAP TPR_1 PF00515.28 EKX51309.1 - 1.7e-06 27.6 7.9 0.12 12.2 0.1 6.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX51309.1 - 0.00025 20.5 7.8 0.023 14.1 4.6 2.6 1 1 1 2 2 2 2 MalT-like TPR region TPR_16 PF13432.6 EKX51309.1 - 0.011 16.4 11.3 4.9 7.9 0.7 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.9 EKX51309.1 - 0.023 14.4 0.6 0.062 13.0 0.6 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain HMGL-like PF00682.19 EKX51309.1 - 0.074 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 HMGL-like NiFeSe_Hases PF00374.19 EKX51309.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 Nickel-dependent hydrogenase TPR_14 PF13428.6 EKX51309.1 - 0.21 12.5 19.1 13 6.9 0.1 6.4 6 2 2 8 8 8 0 Tetratricopeptide repeat TPR_9 PF13371.6 EKX51309.1 - 1.8 8.7 14.2 8.7 6.6 0.7 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 EKX51310.1 - 5.7e-10 38.5 4.5 0.00063 19.7 0.9 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX51310.1 - 1.2e-07 31.2 1.1 0.00034 20.3 0.5 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX51310.1 - 8.1e-07 28.8 0.0 0.00065 19.7 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX51310.1 - 2.4e-06 27.9 1.8 0.05 14.4 0.1 4.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX51310.1 - 6.5e-06 26.7 4.6 0.00072 20.2 1.8 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX51310.1 - 2.4e-05 23.9 3.0 0.00018 21.1 0.2 2.6 1 1 1 2 2 2 1 TPR repeat TPR_17 PF13431.6 EKX51310.1 - 7.9e-05 22.8 0.6 0.0095 16.3 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX51310.1 - 0.0056 17.2 3.4 4.3 8.2 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX51310.1 - 0.0079 16.7 2.2 0.087 13.4 0.2 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX51310.1 - 0.025 14.6 0.5 1.7 8.9 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX51310.1 - 0.21 11.9 2.5 2.4 8.5 1.2 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat EGF_2 PF07974.13 EKX51310.1 - 0.41 11.0 3.4 0.86 10.0 3.4 1.6 1 0 0 1 1 1 0 EGF-like domain TPR_10 PF13374.6 EKX51310.1 - 2 8.4 4.4 3 7.8 1.6 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat LRR_6 PF13516.6 EKX51311.1 - 7.6e-30 100.4 37.3 0.00024 20.9 0.0 11.1 11 0 0 11 11 11 9 Leucine Rich repeat LRR_4 PF12799.7 EKX51311.1 - 2.5e-16 59.5 26.5 9.8e-05 22.7 5.6 7.3 3 2 4 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX51311.1 - 2.2e-14 53.0 38.9 0.00044 20.0 13.2 7.7 4 4 2 6 6 6 4 Leucine rich repeat LRR_1 PF00560.33 EKX51311.1 - 3.2e-08 33.0 27.4 1.2 10.0 0.0 10.1 10 0 0 10 10 10 3 Leucine Rich Repeat LRR_9 PF14580.6 EKX51311.1 - 4.5e-06 26.3 0.0 0.85 9.1 0.0 3.7 1 1 0 3 3 3 2 Leucine-rich repeat Peptidase_C1 PF00112.23 EKX51312.1 - 8.5e-57 192.7 0.1 1.3e-56 192.1 0.1 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EKX51312.1 - 0.0026 16.6 0.8 0.21 10.3 0.2 2.2 2 0 0 2 2 2 2 Peptidase C1-like family WD40 PF00400.32 EKX51314.1 - 4.1e-21 74.9 7.0 4.4e-07 30.5 0.2 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX51314.1 - 2.6e-06 27.6 0.3 0.19 12.0 0.0 4.9 5 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EKX51314.1 - 0.00093 18.8 0.1 0.007 16.0 0.0 2.5 3 0 0 3 3 3 1 PQQ-like domain RNA_polI_A34 PF08208.11 EKX51314.1 - 0.0011 19.1 2.3 0.0022 18.1 2.3 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 Vfa1 PF08432.10 EKX51314.1 - 0.031 14.6 5.1 0.065 13.6 5.1 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TFIIA PF03153.13 EKX51314.1 - 0.27 11.2 21.2 0.5 10.3 21.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PPL5 PF18168.1 EKX51314.1 - 0.31 10.3 2.6 0.59 9.4 2.6 1.4 1 0 0 1 1 1 0 Prim-pol family 5 Nop14 PF04147.12 EKX51314.1 - 0.37 8.9 35.7 0.56 8.4 35.7 1.1 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.12 EKX51314.1 - 0.38 9.7 2.4 0.67 8.9 2.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) BUD22 PF09073.10 EKX51314.1 - 3.3 7.0 29.1 7.5 5.8 29.1 1.5 1 0 0 1 1 1 0 BUD22 RNA_pol_Rpc4 PF05132.14 EKX51314.1 - 4.2 7.8 5.9 13 6.2 5.9 1.8 1 0 0 1 1 1 0 RNA polymerase III RPC4 NPR3 PF03666.13 EKX51314.1 - 5.1 5.8 10.8 9.9 4.8 10.8 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Mpp10 PF04006.12 EKX51314.1 - 9.1 4.6 28.6 15 3.9 28.6 1.2 1 0 0 1 1 1 0 Mpp10 protein Pkinase_Tyr PF07714.17 EKX51315.1 - 1.4e-55 188.4 0.0 1.7e-55 188.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX51315.1 - 1.1e-47 162.6 0.0 1.4e-47 162.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EKX51315.1 - 0.0024 17.3 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EKX51315.1 - 0.0097 14.7 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX51315.1 - 0.024 14.6 0.1 0.18 11.7 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family FixQ PF05545.11 EKX51315.1 - 0.16 11.9 0.1 0.42 10.6 0.1 1.7 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Guanylate_cyc PF00211.20 EKX51316.1 - 7.1e-45 152.9 0.1 8.1e-45 152.7 0.1 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain T2SS_PulS_OutS PF09691.10 EKX51317.1 - 0.077 13.2 0.0 3.5 7.8 0.0 2.2 1 1 1 2 2 2 0 Type II secretion system pilotin lipoprotein (PulS_OutS) Homeodomain PF00046.29 EKX51318.1 - 3.3e-06 26.9 0.2 7.5e-06 25.7 0.2 1.6 1 0 0 1 1 1 1 Homeodomain Thioredoxin PF00085.20 EKX51319.1 - 7.9e-13 48.3 0.0 1.6e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin DIM1 PF02966.16 EKX51319.1 - 0.00044 20.0 0.1 0.00082 19.2 0.1 1.4 1 0 0 1 1 1 1 Mitosis protein DIM1 OST3_OST6 PF04756.13 EKX51319.1 - 0.0046 16.4 0.0 0.0065 15.8 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 EKX51319.1 - 0.036 14.1 0.0 0.08 13.0 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_7 PF13899.6 EKX51319.1 - 0.061 13.5 0.2 0.11 12.7 0.2 1.4 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.6 EKX51319.1 - 0.12 12.8 0.1 0.42 11.1 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain Ntox47 PF15540.6 EKX51321.1 - 0.046 14.0 0.2 0.68 10.2 0.0 2.3 2 1 0 2 2 2 0 Bacterial toxin 47 malic PF00390.19 EKX51321.1 - 0.086 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, N-terminal domain HA PF03457.14 EKX51322.1 - 2.1e-12 47.2 0.0 4.7e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain Agenet PF05641.12 EKX51322.1 - 0.031 14.7 0.1 0.031 14.7 0.1 2.1 2 0 0 2 2 2 0 Agenet domain HPP PF04982.13 EKX51323.1 - 1.6e-08 34.7 1.1 1.6e-08 34.7 1.1 1.4 2 0 0 2 2 2 1 HPP family RXT2_N PF08595.11 EKX51324.1 - 0.0054 16.8 6.7 0.0059 16.6 6.7 1.1 1 0 0 1 1 1 1 RXT2-like, N-terminal Sigma70_ner PF04546.13 EKX51324.1 - 0.0086 16.0 8.6 0.0086 16.0 8.6 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region RRN3 PF05327.11 EKX51324.1 - 0.017 13.7 6.6 0.015 13.9 6.6 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PTPRCAP PF15713.5 EKX51324.1 - 0.025 14.9 9.9 0.029 14.6 9.9 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated RPA43_OB PF17875.1 EKX51324.1 - 0.028 15.0 1.6 0.031 14.9 1.6 1.2 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I PPP4R2 PF09184.11 EKX51324.1 - 0.03 13.9 12.5 0.031 13.9 12.5 1.1 1 0 0 1 1 1 0 PPP4R2 RNA_pol_3_Rpc31 PF11705.8 EKX51324.1 - 0.049 13.9 19.5 0.052 13.8 19.5 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CobT PF06213.12 EKX51324.1 - 0.11 11.8 12.9 0.13 11.7 12.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CENP-B_dimeris PF09026.10 EKX51324.1 - 0.15 12.5 24.4 0.23 11.9 24.4 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 EKX51324.1 - 0.18 11.1 21.4 0.22 10.8 21.4 1.0 1 0 0 1 1 1 0 NOA36 protein GCIP PF13324.6 EKX51324.1 - 0.22 11.1 6.4 0.22 11.1 6.4 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting HSP90 PF00183.18 EKX51324.1 - 0.25 10.2 8.4 0.28 10.0 8.4 1.0 1 0 0 1 1 1 0 Hsp90 protein TRAP_alpha PF03896.16 EKX51324.1 - 0.28 10.3 6.9 0.3 10.2 6.9 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SURF2 PF05477.11 EKX51324.1 - 0.31 10.7 6.5 0.35 10.5 6.5 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF913 PF06025.12 EKX51324.1 - 0.32 9.9 3.6 0.35 9.8 3.6 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TFB6 PF17110.5 EKX51324.1 - 0.41 10.4 9.0 0.48 10.2 9.0 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DNA_pol_phi PF04931.13 EKX51324.1 - 0.44 8.6 25.7 0.5 8.4 25.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi GP67 PF17634.2 EKX51324.1 - 0.45 11.0 28.4 0.67 10.4 28.4 1.2 1 0 0 1 1 1 0 Gene product 67 DUF2722 PF10846.8 EKX51324.1 - 0.47 9.3 5.4 0.47 9.3 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RPN2_C PF18004.1 EKX51324.1 - 0.49 10.3 7.7 0.57 10.1 7.7 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4637 PF15470.6 EKX51324.1 - 0.8 9.4 11.5 0.93 9.2 11.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CDC45 PF02724.14 EKX51324.1 - 1.1 7.5 15.6 1.2 7.4 15.6 1.0 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 EKX51324.1 - 1.2 8.5 18.2 1.3 8.4 18.2 1.0 1 0 0 1 1 1 0 SDA1 SGT1 PF07093.11 EKX51324.1 - 1.3 7.3 10.5 1.3 7.3 10.5 1.0 1 0 0 1 1 1 0 SGT1 protein Nop14 PF04147.12 EKX51324.1 - 1.6 6.8 19.7 1.8 6.7 19.7 1.0 1 0 0 1 1 1 0 Nop14-like family MRNIP PF15749.5 EKX51324.1 - 1.8 9.3 5.2 2.1 9.1 5.2 1.1 1 0 0 1 1 1 0 MRN-interacting protein BUD22 PF09073.10 EKX51324.1 - 1.9 7.8 13.8 2.1 7.6 13.8 1.0 1 0 0 1 1 1 0 BUD22 AIM3 PF17096.5 EKX51324.1 - 3 8.8 6.6 5 8.1 6.6 1.4 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 DUF2457 PF10446.9 EKX51324.1 - 3.2 6.8 28.4 3.8 6.6 28.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Paf1 PF03985.13 EKX51324.1 - 3.5 6.5 13.7 3.8 6.4 13.7 1.0 1 0 0 1 1 1 0 Paf1 Nop53 PF07767.11 EKX51324.1 - 5.5 6.3 14.6 6.4 6.1 14.6 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Pox_Ag35 PF03286.14 EKX51324.1 - 6.2 6.6 14.4 8.1 6.2 14.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Cwf_Cwc_15 PF04889.12 EKX51324.1 - 6.2 6.5 21.4 7.5 6.2 21.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Big_3 PF07523.12 EKX51325.1 - 0.025 14.9 0.0 0.04 14.2 0.0 1.3 1 1 0 1 1 1 0 Bacterial Ig-like domain (group 3) PIP5K PF01504.18 EKX51326.1 - 1.5e-36 126.0 0.1 1.9e-36 125.7 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase HTH_19 PF12844.7 EKX51326.1 - 0.1 12.6 0.0 9.6 6.3 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Prenyltrans PF00432.21 EKX51327.1 - 6.7e-23 80.1 28.0 4.1e-11 42.4 0.2 5.9 6 1 0 6 6 6 3 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EKX51327.1 - 5.7e-06 25.6 0.0 0.035 13.2 0.0 2.2 1 1 1 2 2 2 2 Squalene-hopene cyclase N-terminal domain EF-hand_1 PF00036.32 EKX51329.1 - 0.0024 17.3 0.0 0.0044 16.5 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 EKX51329.1 - 0.047 13.2 0.1 0.09 12.3 0.1 1.5 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 EKX51329.1 - 0.05 13.6 0.2 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 EKX51329.1 - 0.053 14.0 0.0 0.18 12.3 0.0 1.8 1 1 1 2 2 2 0 EF-hand domain pair DUF5111 PF17138.4 EKX51329.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5111) SPARC_Ca_bdg PF10591.9 EKX51329.1 - 0.14 12.5 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region mTERF PF02536.14 EKX51331.1 - 3.1e-45 154.5 0.9 3.7e-45 154.2 0.9 1.1 1 0 0 1 1 1 1 mTERF CDC50 PF03381.15 EKX51334.1 - 1.3e-59 202.1 1.9 5.4e-59 200.0 1.9 2.0 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Bac_export_3 PF01313.19 EKX51334.1 - 0.17 11.8 0.0 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial export proteins, family 3 DUF202 PF02656.15 EKX51334.1 - 0.34 11.4 2.3 15 6.1 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) CD20 PF04103.15 EKX51334.1 - 1 9.5 5.7 14 5.7 0.1 2.2 2 0 0 2 2 2 0 CD20-like family DUF2157 PF09925.9 EKX51334.1 - 1.1 9.0 4.7 9.7 6.0 1.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) SANTA PF09133.10 EKX51335.1 - 4.2e-19 68.8 0.1 9.7e-19 67.7 0.1 1.7 1 0 0 1 1 1 1 SANTA (SANT Associated) Myb_DNA-binding PF00249.31 EKX51335.1 - 0.00034 20.8 0.0 0.00078 19.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain UPF0181 PF03701.14 EKX51336.1 - 0.00032 20.2 0.3 0.00073 19.1 0.3 1.6 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0181) Ank_2 PF12796.7 EKX51337.1 - 1.9e-11 44.4 0.2 1.9e-11 44.4 0.2 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX51337.1 - 5.1e-11 42.5 1.8 4e-06 27.0 0.2 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EKX51337.1 - 3.2e-10 40.3 0.2 3.6e-10 40.2 0.2 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX51337.1 - 3.7e-07 30.3 0.1 4.4e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX51337.1 - 7.9e-07 28.9 0.6 0.0011 19.3 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeat CDC45 PF02724.14 EKX51338.1 - 1.9e-05 23.2 22.6 2.1e-05 23.1 22.6 1.0 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 EKX51338.1 - 4.9e-05 21.8 21.8 5.1e-05 21.7 21.8 1.0 1 0 0 1 1 1 1 Nop14-like family SpoIIIAH PF12685.7 EKX51338.1 - 0.00027 20.8 4.4 0.00029 20.7 4.4 1.0 1 0 0 1 1 1 1 SpoIIIAH-like protein SDA1 PF05285.12 EKX51338.1 - 0.0058 16.1 26.8 0.0068 15.9 26.8 1.0 1 0 0 1 1 1 1 SDA1 REV PF00424.18 EKX51338.1 - 0.0091 16.0 1.5 0.0091 16.0 1.5 1.8 2 0 0 2 2 2 1 REV protein (anti-repression trans-activator protein) BUD22 PF09073.10 EKX51338.1 - 0.0094 15.3 21.5 0.011 15.2 21.5 1.1 1 0 0 1 1 1 1 BUD22 RR_TM4-6 PF06459.12 EKX51338.1 - 0.018 14.9 14.7 0.021 14.6 14.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_11 PF13086.6 EKX51338.1 - 0.021 14.6 8.3 0.023 14.5 8.3 1.0 1 0 0 1 1 1 0 AAA domain Mpp10 PF04006.12 EKX51338.1 - 0.026 13.0 29.7 0.033 12.7 29.7 1.1 1 0 0 1 1 1 0 Mpp10 protein Zip PF02535.22 EKX51338.1 - 0.042 13.1 5.2 0.048 12.9 5.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Serinc PF03348.15 EKX51338.1 - 0.044 12.7 3.3 0.055 12.4 3.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) MCM_bind PF09739.9 EKX51338.1 - 0.048 12.1 5.9 0.054 11.9 5.9 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF913 PF06025.12 EKX51338.1 - 0.049 12.6 5.9 0.054 12.5 5.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FYDLN_acid PF09538.10 EKX51338.1 - 0.062 14.0 23.0 0.1 13.3 23.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Vfa1 PF08432.10 EKX51338.1 - 0.11 12.8 17.0 0.16 12.3 17.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NPR3 PF03666.13 EKX51338.1 - 0.11 11.2 12.9 0.14 10.9 12.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CLN3 PF02487.17 EKX51338.1 - 0.13 11.3 0.6 0.14 11.2 0.6 1.1 1 0 0 1 1 1 0 CLN3 protein Spore_coat_CotO PF14153.6 EKX51338.1 - 0.14 12.1 11.4 0.16 11.9 11.4 1.1 1 0 0 1 1 1 0 Spore coat protein CotO SpoIIP PF07454.11 EKX51338.1 - 0.16 11.4 8.9 0.19 11.2 8.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 EKX51338.1 - 0.19 10.4 11.6 0.23 10.2 11.6 1.1 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 EKX51338.1 - 0.19 11.7 6.8 0.25 11.3 6.8 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DNA_pol_phi PF04931.13 EKX51338.1 - 0.22 9.6 39.5 0.26 9.4 39.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi SID-1_RNA_chan PF13965.6 EKX51338.1 - 0.22 9.9 1.4 0.24 9.8 1.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SLC12 PF03522.15 EKX51338.1 - 0.28 10.1 6.0 0.31 10.0 6.0 1.0 1 0 0 1 1 1 0 Solute carrier family 12 PI3K_1B_p101 PF10486.9 EKX51338.1 - 0.32 8.7 8.1 0.4 8.4 8.1 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit YL1 PF05764.13 EKX51338.1 - 0.33 11.0 35.8 0.41 10.7 35.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 EKX51338.1 - 0.38 10.5 33.1 0.46 10.2 33.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DDHD PF02862.17 EKX51338.1 - 0.63 10.2 3.2 0.75 9.9 3.2 1.2 1 0 0 1 1 1 0 DDHD domain TRAP_alpha PF03896.16 EKX51338.1 - 0.63 9.2 14.8 0.81 8.8 14.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RNA_pol_Rpc4 PF05132.14 EKX51338.1 - 0.69 10.3 8.9 0.91 9.9 8.9 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF2076 PF09849.9 EKX51338.1 - 0.88 9.6 10.1 0.94 9.5 10.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF2151 PF10221.9 EKX51338.1 - 1.1 7.7 10.4 1.3 7.6 10.4 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator DUF2722 PF10846.8 EKX51338.1 - 1.2 8.0 15.0 1.5 7.7 15.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Tim54 PF11711.8 EKX51338.1 - 1.4 7.7 12.5 1.7 7.4 12.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3381 PF11861.8 EKX51338.1 - 1.4 8.7 26.7 1.8 8.4 26.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF2457 PF10446.9 EKX51338.1 - 1.6 7.8 40.9 2 7.5 40.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) V_ATPase_I PF01496.19 EKX51338.1 - 1.6 6.5 11.7 1.8 6.4 11.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ALMT PF11744.8 EKX51338.1 - 1.6 7.5 3.7 1.7 7.3 3.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter IFT57 PF10498.9 EKX51338.1 - 1.6 7.6 17.0 1.8 7.4 17.0 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Merozoite_SPAM PF07133.11 EKX51338.1 - 1.7 8.6 41.5 2.1 8.3 41.5 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SAPS PF04499.15 EKX51338.1 - 1.9 7.2 13.3 2.1 7.0 13.3 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Apt1 PF10351.9 EKX51338.1 - 2 7.2 10.5 2.3 7.0 10.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Slu7 PF11708.8 EKX51338.1 - 2.8 7.6 24.7 3.4 7.4 24.7 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Hid1 PF12722.7 EKX51338.1 - 3.5 5.6 8.7 3.9 5.5 8.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RNA_polI_A34 PF08208.11 EKX51338.1 - 3.7 7.6 18.3 4.5 7.3 18.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 FAM176 PF14851.6 EKX51338.1 - 3.7 7.2 31.0 4 7.1 16.6 2.1 1 1 1 2 2 2 0 FAM176 family DUF4337 PF14235.6 EKX51338.1 - 4.2 7.5 5.8 4.7 7.3 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) TFIIA PF03153.13 EKX51338.1 - 5.2 7.0 22.8 6.1 6.7 22.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Paf1 PF03985.13 EKX51338.1 - 6.3 5.7 31.2 7.5 5.4 31.2 1.0 1 0 0 1 1 1 0 Paf1 MDM10 PF12519.8 EKX51338.1 - 7.1 5.4 6.2 7.6 5.3 6.2 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 COPI_C PF06957.11 EKX51338.1 - 7.4 5.2 11.1 8.3 5.0 11.1 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Eapp_C PF10238.9 EKX51338.1 - 7.7 6.6 18.8 0.2 11.7 0.5 2.1 1 1 1 2 2 1 0 E2F-associated phosphoprotein Nop53 PF07767.11 EKX51338.1 - 8.9 5.6 32.7 11 5.3 32.7 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF789 PF05623.12 EKX51338.1 - 9.3 5.8 9.6 12 5.5 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF789) Trypan_PARP PF05887.11 EKX51338.1 - 10 6.1 14.3 12 5.8 14.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TTL PF03133.15 EKX51340.1 - 5.7e-98 327.7 0.1 7.8e-98 327.2 0.1 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EKX51340.1 - 6.5e-07 28.9 0.1 0.00016 21.0 0.0 2.8 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EKX51340.1 - 0.00044 19.6 0.0 0.0045 16.3 0.0 2.4 3 0 0 3 3 3 1 Sugar-transfer associated ATP-grasp GCK PF07802.11 EKX51341.1 - 4.2e-08 33.5 6.2 4.2e-08 33.5 6.2 1.8 3 0 0 3 3 3 1 GCK domain ORC_WH_C PF18137.1 EKX51341.1 - 0.043 13.9 3.0 0.06 13.4 3.0 1.3 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal CHCH PF06747.13 EKX51341.1 - 2.1 8.6 9.0 0.31 11.2 4.5 2.1 2 0 0 2 2 2 0 CHCH domain Voldacs PF03517.13 EKX51341.1 - 3.2 7.9 10.5 3.2 7.9 9.6 1.5 1 1 0 1 1 1 0 Regulator of volume decrease after cellular swelling CDC45 PF02724.14 EKX51341.1 - 5.5 5.2 9.6 5.9 5.1 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 EKX51341.1 - 6.8 6.3 7.2 9.2 5.9 7.2 1.3 1 0 0 1 1 1 0 FAM176 family Tropomyosin_1 PF12718.7 EKX51342.1 - 0.0032 17.6 2.0 0.0066 16.6 2.0 1.4 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 EKX51342.1 - 0.0075 15.7 1.3 0.013 14.9 1.3 1.3 1 0 0 1 1 1 1 Tropomyosin TOM20_plant PF06552.12 EKX51343.1 - 6.5e-19 68.4 7.8 5.4e-10 39.3 0.0 2.9 2 1 1 3 3 3 2 Plant specific mitochondrial import receptor subunit TOM20 TPR_2 PF07719.17 EKX51343.1 - 0.052 13.7 5.5 6.7 7.1 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DivIC PF04977.15 EKX51343.1 - 0.14 11.9 3.2 0.66 9.8 3.2 2.2 1 0 0 1 1 1 0 Septum formation initiator Trypan_PARP PF05887.11 EKX51343.1 - 0.17 11.8 6.8 0.34 10.9 6.8 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CiPC PF15800.5 EKX51343.1 - 0.56 9.9 12.8 2.8 7.6 6.9 2.1 2 0 0 2 2 2 0 Clock interacting protein circadian TPR_1 PF00515.28 EKX51343.1 - 2.6 8.0 5.7 97 3.0 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat GAS PF13851.6 EKX51344.1 - 2e-30 105.7 9.9 2e-30 105.7 9.9 2.9 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding Golgin_A5 PF09787.9 EKX51344.1 - 0.0014 18.2 44.8 0.031 13.8 29.2 2.2 1 1 1 2 2 2 2 Golgin subfamily A member 5 Baculo_PEP_C PF04513.12 EKX51344.1 - 0.15 12.1 6.4 22 5.1 0.6 3.7 2 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.8 EKX51344.1 - 0.17 9.4 39.2 0.21 9.1 39.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ApoO PF09769.9 EKX51344.1 - 0.27 11.2 6.7 12 5.8 1.3 3.4 1 1 1 2 2 2 0 Apolipoprotein O HA PF03457.14 EKX51347.1 - 2.1e-13 50.4 1.9 5.6e-13 49.0 1.9 1.7 1 0 0 1 1 1 1 Helicase associated domain zf-CW PF07496.15 EKX51347.1 - 7.3e-06 25.9 1.8 2.2e-05 24.4 1.8 1.8 1 0 0 1 1 1 1 CW-type Zinc Finger CdhD PF03599.16 EKX51347.1 - 0.15 10.7 0.3 0.63 8.7 0.0 1.9 2 0 0 2 2 2 0 CO dehydrogenase/acetyl-CoA synthase delta subunit NOA36 PF06524.12 EKX51347.1 - 5.6 6.2 22.5 0.3 10.3 16.2 2.0 2 0 0 2 2 2 0 NOA36 protein VWA PF00092.28 EKX51348.1 - 2.9e-06 27.7 0.0 3e-05 24.3 0.0 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EKX51348.1 - 2.3e-05 25.0 0.0 7.8e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EKX51348.1 - 0.094 12.7 0.3 1 9.3 0.0 2.7 4 0 0 4 4 4 0 von Willebrand factor type A domain SNF2_N PF00176.23 EKX51349.1 - 1.9e-62 211.0 0.3 3.6e-62 210.1 0.1 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX51349.1 - 3.1e-20 72.6 0.0 8.3e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EKX51349.1 - 1.2e-05 25.2 0.0 2.8e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EKX51349.1 - 0.00035 20.6 0.0 0.0014 18.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EKX51349.1 - 0.00045 19.5 0.4 0.0035 16.5 0.0 2.1 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DUF4020 PF13212.6 EKX51349.1 - 0.0037 17.1 0.4 0.014 15.2 0.2 2.0 1 1 0 2 2 2 1 Domain of unknown function (DUF4020) EF-hand_8 PF13833.6 EKX51350.1 - 4.5e-08 32.8 1.0 8.2e-08 32.0 0.3 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX51350.1 - 9.9e-08 31.0 0.3 1.8e-07 30.2 0.3 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EKX51350.1 - 1.3e-05 25.5 0.1 2.7e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX51350.1 - 0.00012 21.7 0.3 0.00027 20.6 0.3 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 EKX51350.1 - 0.00036 19.9 0.3 0.00069 19.0 0.3 1.5 1 0 0 1 1 1 1 EF hand DSPc PF00782.20 EKX51351.1 - 7.7e-07 29.0 0.0 9.4e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX51351.1 - 0.00017 21.3 0.0 0.0002 21.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX51351.1 - 0.0014 18.8 0.0 0.002 18.3 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EKX51351.1 - 0.014 15.4 0.0 0.015 15.3 0.0 1.1 1 0 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.12 EKX51351.1 - 0.035 13.8 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) SH3_1 PF00018.28 EKX51352.1 - 0.035 13.7 0.0 0.094 12.3 0.0 1.8 1 0 0 1 1 1 0 SH3 domain SH3_2 PF07653.17 EKX51352.1 - 0.088 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Par3_HAL_N_term PF12053.8 EKX51352.1 - 0.68 10.2 2.6 1.6 9.0 0.2 2.9 3 0 0 3 3 3 0 N-terminal of Par3 and HAL proteins HSBP1 PF06825.12 EKX51353.1 - 2.5e-06 27.2 13.7 0.031 14.1 2.3 4.1 5 0 0 5 5 5 2 Heat shock factor binding protein 1 Sugarporin_N PF11471.8 EKX51353.1 - 0.0001 22.1 2.5 0.98 9.4 0.0 4.4 5 0 0 5 5 4 1 Maltoporin periplasmic N-terminal extension Osmo_CC PF08946.10 EKX51353.1 - 0.0024 18.1 10.0 1.8 8.9 0.0 4.2 3 1 1 4 4 4 1 Osmosensory transporter coiled coil CLZ PF16526.5 EKX51353.1 - 0.0026 18.1 9.1 0.16 12.3 5.5 3.7 2 2 1 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels BLOC1_2 PF10046.9 EKX51353.1 - 0.0026 18.0 2.1 1 9.7 1.2 3.2 2 2 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cast PF10174.9 EKX51353.1 - 0.0048 15.2 0.1 0.0063 14.8 0.1 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Jnk-SapK_ap_N PF09744.9 EKX51353.1 - 0.0061 16.8 1.8 0.01 16.0 1.8 1.3 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 DUF241 PF03087.14 EKX51353.1 - 0.0093 15.8 0.1 0.43 10.4 0.1 2.6 3 0 0 3 3 3 1 Arabidopsis protein of unknown function XhlA PF10779.9 EKX51353.1 - 0.03 14.5 11.5 3.9 7.8 1.9 4.4 3 1 1 4 4 4 0 Haemolysin XhlA Laminin_II PF06009.12 EKX51353.1 - 0.037 14.1 0.9 0.5 10.4 0.5 2.5 2 0 0 2 2 2 0 Laminin Domain II FlaC_arch PF05377.11 EKX51353.1 - 0.052 14.0 6.2 79 3.8 0.0 4.3 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Snapin_Pallidin PF14712.6 EKX51353.1 - 0.057 13.8 4.3 28 5.2 0.5 4.1 2 2 0 3 3 3 0 Snapin/Pallidin Dynamitin PF04912.14 EKX51353.1 - 0.06 12.7 9.5 19 4.4 4.9 3.5 1 1 1 2 2 2 0 Dynamitin UPF0184 PF03670.13 EKX51353.1 - 0.068 13.6 0.4 5.2 7.5 0.0 2.8 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0184) TBCC_N PF16752.5 EKX51353.1 - 0.089 13.2 0.8 16 6.0 0.2 3.1 2 1 1 3 3 3 0 Tubulin-specific chaperone C N-terminal domain RP-C_C PF11800.8 EKX51353.1 - 0.14 12.2 0.1 4.2 7.4 0.0 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region DUF1664 PF07889.12 EKX51353.1 - 0.15 12.1 0.6 1.2 9.2 0.5 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) SlyX PF04102.12 EKX51353.1 - 0.15 12.7 11.0 17 6.1 0.2 3.9 3 1 1 4 4 3 0 SlyX DUF4795 PF16043.5 EKX51353.1 - 0.17 11.5 1.6 0.79 9.3 1.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Cauli_AT PF03233.13 EKX51353.1 - 0.18 11.7 1.2 0.99 9.3 0.4 2.2 2 0 0 2 2 2 0 Aphid transmission protein TolA_bind_tri PF16331.5 EKX51353.1 - 0.2 11.8 7.5 0.89 9.7 2.6 3.5 2 2 0 3 3 3 0 TolA binding protein trimerisation phiKZ_IP PF12699.7 EKX51353.1 - 0.27 10.3 1.6 1.7 7.7 1.5 2.3 1 1 1 2 2 2 0 phiKZ-like phage internal head proteins Cnn_1N PF07989.11 EKX51353.1 - 0.29 11.3 3.6 12 6.1 3.1 3.0 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 ACCA PF03255.14 EKX51353.1 - 0.31 10.9 2.4 1.4 8.8 1.8 2.2 2 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit S6OS1 PF15676.5 EKX51353.1 - 0.31 9.5 1.0 0.44 9.0 1.0 1.1 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family Macoilin PF09726.9 EKX51353.1 - 0.31 9.5 1.1 0.48 8.9 1.1 1.2 1 0 0 1 1 1 0 Macoilin family TRAF_BIRC3_bd PF16673.5 EKX51353.1 - 0.44 10.4 4.7 2.1 8.2 3.7 2.4 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain MtrG PF04210.13 EKX51353.1 - 0.62 10.0 2.3 7.3 6.5 0.0 2.9 3 0 0 3 3 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF2730 PF10805.8 EKX51353.1 - 0.89 9.7 3.6 5.6 7.1 0.9 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) Dynactin_p22 PF07426.11 EKX51353.1 - 1.1 9.1 11.0 17 5.2 0.5 3.7 2 2 2 4 4 4 0 Dynactin subunit p22 ABC_tran_CTD PF16326.5 EKX51353.1 - 1.2 9.4 12.6 10 6.5 3.2 4.0 2 2 1 3 3 3 0 ABC transporter C-terminal domain Rx_N PF18052.1 EKX51353.1 - 1.5 9.1 4.4 5.3 7.4 3.6 2.1 2 0 0 2 2 2 0 Rx N-terminal domain Uds1 PF15456.6 EKX51353.1 - 2.4 8.3 5.1 1.1 9.5 1.2 2.3 3 0 0 3 3 2 0 Up-regulated During Septation Prefoldin_2 PF01920.20 EKX51353.1 - 2.9 7.9 4.9 24 4.9 1.4 3.2 2 1 0 2 2 2 0 Prefoldin subunit BRI3BP PF14965.6 EKX51353.1 - 3.7 7.0 4.7 8.8 5.8 1.7 3.1 3 1 0 3 3 3 0 Negative regulator of p53/TP53 DUF4315 PF14193.6 EKX51353.1 - 7.6 6.6 7.2 9.4 6.3 2.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4315) Sulfotransfer_1 PF00685.27 EKX51355.1 - 4.1e-23 82.2 0.2 5.1e-23 81.9 0.2 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EKX51355.1 - 0.0009 19.7 0.0 0.0014 19.0 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family DUF3473 PF11959.8 EKX51355.1 - 0.0049 16.9 0.1 0.0093 16.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3473) DUF2072 PF09845.9 EKX51355.1 - 0.093 13.0 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Zn-ribbon containing protein Thioredoxin PF00085.20 EKX51357.1 - 7.9e-29 99.7 0.1 1e-28 99.3 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EKX51357.1 - 3.5e-08 33.9 0.1 5.6e-07 30.0 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EKX51357.1 - 2.9e-07 30.7 0.0 1.3e-06 28.6 0.0 1.8 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 EKX51357.1 - 4e-07 30.0 0.0 5.6e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 EKX51357.1 - 1.9e-06 27.9 0.1 3.2e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 EKX51357.1 - 1.6e-05 24.6 0.0 2.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_6 PF13848.6 EKX51357.1 - 3e-05 24.0 0.0 3.8e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EKX51357.1 - 0.003 17.3 0.1 0.0036 17.1 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EKX51357.1 - 0.015 14.7 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family TraF PF13728.6 EKX51357.1 - 0.023 14.5 0.0 0.029 14.2 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Proteasome PF00227.26 EKX51358.1 - 7.4e-35 120.2 0.0 9.2e-35 119.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit AAA PF00004.29 EKX51359.1 - 7.3e-39 133.2 0.0 1.3e-38 132.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EKX51359.1 - 9.4e-09 34.9 0.2 1.8e-08 34.0 0.2 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EKX51359.1 - 1.9e-08 34.1 0.2 4.3e-08 33.0 0.0 1.7 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 EKX51359.1 - 3.3e-05 24.2 0.2 0.0026 18.0 0.2 2.3 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EKX51359.1 - 7.3e-05 22.0 0.0 0.00017 20.9 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EKX51359.1 - 0.00016 21.4 0.0 0.00033 20.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EKX51359.1 - 0.00034 21.0 0.1 0.0011 19.3 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 EKX51359.1 - 0.00079 19.6 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EKX51359.1 - 0.0012 18.9 0.0 0.0027 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EKX51359.1 - 0.003 17.3 0.0 0.0056 16.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 EKX51359.1 - 0.0045 17.2 0.0 0.0093 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EKX51359.1 - 0.0075 16.5 0.4 0.022 15.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 EKX51359.1 - 0.0092 15.2 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 EKX51359.1 - 0.01 16.2 0.0 0.026 14.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 EKX51359.1 - 0.012 16.2 0.0 0.032 14.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EKX51359.1 - 0.016 14.6 0.1 0.029 13.8 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 EKX51359.1 - 0.019 14.4 0.1 0.094 12.2 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.11 EKX51359.1 - 0.036 13.9 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EKX51359.1 - 0.05 13.3 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EKX51359.1 - 0.058 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EKX51359.1 - 0.086 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EKX51359.1 - 0.098 12.4 0.2 0.26 11.0 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EKX51359.1 - 0.11 12.0 0.0 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EKX51359.1 - 0.11 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 EKX51359.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 S10_plectin PF03501.15 EKX51360.1 - 2.8e-40 136.3 0.5 3.3e-40 136.0 0.5 1.0 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.19 EKX51360.1 - 0.028 14.3 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB CK_II_beta PF01214.18 EKX51361.1 - 0.048 13.5 0.7 0.09 12.6 0.7 1.3 1 0 0 1 1 1 0 Casein kinase II regulatory subunit Troponin PF00992.20 EKX51362.1 - 0.11 12.8 1.2 2.1 8.6 0.1 2.0 1 1 1 2 2 2 0 Troponin GSH_synth_ATP PF03917.17 EKX51365.1 - 1.5e-108 363.0 0.0 1.6e-108 362.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EKX51365.1 - 8.3e-28 96.9 0.0 2.2e-27 95.5 0.0 1.7 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Peptidase_C26 PF07722.13 EKX51365.1 - 0.009 15.8 0.0 0.37 10.5 0.0 2.5 2 1 1 3 3 3 1 Peptidase C26 ATPgrasp_TupA PF14305.6 EKX51365.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 TupA-like ATPgrasp DUF2890 PF11081.8 EKX51366.1 - 0.0042 17.2 0.2 0.0059 16.7 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) Malic_M PF03949.15 EKX51367.1 - 2.7e-89 298.8 0.0 3.6e-89 298.5 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EKX51367.1 - 2.5e-68 229.5 0.0 3.5e-68 229.0 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain WSD PF15613.6 EKX51370.1 - 1e-09 38.7 0.1 1e-09 38.7 0.1 3.6 4 0 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif MBD PF01429.19 EKX51370.1 - 1.3e-08 34.4 0.5 0.032 13.9 0.0 3.7 3 0 0 3 3 3 2 Methyl-CpG binding domain PHD PF00628.29 EKX51370.1 - 1.7e-06 27.8 7.6 5.1e-06 26.3 7.6 1.9 1 0 0 1 1 1 1 PHD-finger WHIM1 PF15612.6 EKX51370.1 - 1.2e-05 24.7 0.0 4e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 HMG_box PF00505.19 EKX51370.1 - 2.7e-05 24.5 2.2 2.7e-05 24.5 2.2 3.2 3 0 0 3 3 3 1 HMG (high mobility group) box PHD_2 PF13831.6 EKX51370.1 - 3.5e-05 23.3 2.6 7.9e-05 22.1 2.6 1.6 1 0 0 1 1 1 1 PHD-finger FYRN PF05964.14 EKX51370.1 - 6.1e-05 22.8 0.0 0.00015 21.6 0.0 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 EKX51370.1 - 0.0093 16.1 0.0 0.049 13.8 0.0 2.3 1 0 0 1 1 1 1 F/Y rich C-terminus OHCU_decarbox PF09349.10 EKX51371.1 - 3.7e-31 108.7 0.1 4.1e-31 108.6 0.1 1.0 1 0 0 1 1 1 1 OHCU decarboxylase TylF PF05711.11 EKX51372.1 - 6.5e-32 110.8 0.0 1.1e-31 110.0 0.0 1.3 1 0 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) EGF PF00008.27 EKX51372.1 - 0.00036 20.8 9.9 0.0011 19.2 9.9 1.9 1 0 0 1 1 1 1 EGF-like domain EGF_2 PF07974.13 EKX51372.1 - 0.014 15.8 12.1 0.033 14.6 12.1 1.7 1 0 0 1 1 1 0 EGF-like domain DUF4399 PF14347.6 EKX51372.1 - 0.021 15.2 0.0 1.8 9.0 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4399) BolA PF01722.18 EKX51372.1 - 0.19 12.0 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 BolA-like protein hEGF PF12661.7 EKX51372.1 - 1 10.1 7.8 3.5 8.4 7.8 2.0 1 0 0 1 1 1 0 Human growth factor-like EGF Pkinase PF00069.25 EKX51374.1 - 2.5e-39 135.3 0.0 4.9e-39 134.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX51374.1 - 3.8e-26 91.9 0.0 7.5e-26 91.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX51374.1 - 0.0011 18.3 0.1 0.14 11.5 0.1 2.2 1 1 0 1 1 1 1 Kinase-like Carb_anhydrase PF00194.21 EKX51375.1 - 4.1e-19 69.1 0.0 6.1e-13 48.9 0.0 2.4 3 0 0 3 3 3 2 Eukaryotic-type carbonic anhydrase DHC_N1 PF08385.12 EKX51376.1 - 2.3e-82 277.5 2.5 4.5e-82 276.5 2.5 1.5 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 EKX51376.1 - 6.1e-36 124.0 0.0 1.1e-35 123.2 0.0 1.3 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EKX51376.1 - 2.3e-34 119.2 6.1 2.3e-34 119.2 6.1 3.5 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EKX51376.1 - 6.8e-18 64.6 0.0 5.9e-13 48.5 0.0 3.3 3 0 0 3 3 3 2 ATP-binding dynein motor region Dynein_AAA_lid PF17852.1 EKX51376.1 - 9e-16 58.1 0.0 3.1e-15 56.4 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_11 PF18198.1 EKX51376.1 - 4.5e-09 36.3 0.0 1.3e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EKX51376.1 - 5.3e-09 36.2 0.2 1.8e-06 28.0 0.0 3.5 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_7 PF12775.7 EKX51376.1 - 1.1e-07 31.5 0.0 1.2e-06 28.1 0.0 2.7 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_16 PF13191.6 EKX51376.1 - 0.00029 21.3 3.4 0.26 11.7 0.0 4.8 3 1 1 4 4 4 1 AAA ATPase domain AAA_lid_1 PF17857.1 EKX51376.1 - 0.00036 20.7 0.0 0.0016 18.6 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain RsgA_GTPase PF03193.16 EKX51376.1 - 0.01 15.8 0.6 24 4.8 0.2 3.9 3 0 0 3 3 3 0 RsgA GTPase AAA_29 PF13555.6 EKX51376.1 - 0.062 13.0 1.7 1.6 8.6 0.3 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_8 PF12780.7 EKX51376.1 - 0.095 12.0 2.9 0.11 11.8 0.0 2.7 3 0 0 3 3 3 0 P-loop containing dynein motor region D4 G-alpha PF00503.20 EKX51376.1 - 0.11 11.6 3.3 1.4 8.0 0.0 3.3 3 0 0 3 3 3 0 G-protein alpha subunit ABC_tran PF00005.27 EKX51376.1 - 0.23 11.9 0.8 24 5.5 0.0 3.5 3 0 0 3 3 3 0 ABC transporter SNX17_FERM_C PF18116.1 EKX51377.1 - 0.66 10.1 3.7 4 7.6 0.7 2.2 1 1 1 2 2 2 0 Sorting Nexin 17 FERM C-terminal domain Chorein_N PF12624.7 EKX51377.1 - 0.71 10.0 7.3 0.77 9.9 6.2 1.6 1 1 1 2 2 2 0 N-terminal region of Chorein or VPS13 TMEM247 PF15444.6 EKX51377.1 - 2.4 8.1 9.2 3.8 7.5 4.5 2.2 1 1 1 2 2 2 0 Transmembrane protein 247 Spore_II_R PF09551.10 EKX51377.1 - 5.8 7.4 7.4 8.9 6.8 7.4 1.3 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) TMPIT PF07851.13 EKX51377.1 - 8.8 5.5 9.1 11 5.1 9.1 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF2615 PF11027.8 EKX51378.1 - 9.3e-07 29.0 0.0 1.1e-06 28.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) Mg_trans_NIPA PF05653.14 EKX51380.1 - 5.4e-42 143.9 21.3 6e-42 143.8 21.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EKX51380.1 - 9.2e-05 22.6 9.3 9.2e-05 22.6 9.3 2.9 2 1 0 2 2 2 1 EamA-like transporter family DUF21 PF01595.20 EKX51381.1 - 1.9e-35 122.2 0.7 3e-35 121.5 0.7 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain DUF5400 PF17379.2 EKX51381.1 - 0.69 10.4 6.9 0.99 9.9 1.3 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5400) Cytomega_UL84 PF06284.11 EKX51382.1 - 0.87 8.0 6.5 1.2 7.6 6.5 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein RNA_pol_3_Rpc31 PF11705.8 EKX51382.1 - 1.4 9.1 14.6 1.9 8.7 14.6 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Glyco_transf_8 PF01501.20 EKX51383.1 - 5.6e-12 45.8 0.2 2.6e-10 40.3 0.2 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 MFS_1 PF07690.16 EKX51384.1 - 1.4e-06 27.5 6.2 1.6e-06 27.3 6.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily LysM PF01476.20 EKX51385.1 - 0.079 13.0 1.2 0.5 10.5 0.0 2.6 2 0 0 2 2 2 0 LysM domain Fcf1 PF04900.12 EKX51385.1 - 0.1 13.0 0.0 0.34 11.3 0.0 1.8 1 0 0 1 1 1 0 Fcf1 PDZ PF00595.24 EKX51386.1 - 1.8e-08 34.6 0.0 3.6e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX51386.1 - 2.9e-08 33.4 0.2 5.6e-08 32.5 0.2 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX51386.1 - 5.3e-05 23.5 0.0 0.00017 21.8 0.0 1.9 2 0 0 2 2 2 1 PDZ domain GEMIN8 PF15348.6 EKX51386.1 - 0.0012 19.2 15.7 0.0017 18.7 15.7 1.1 1 0 0 1 1 1 1 Gemini of Cajal bodies-associated protein 8 Peptidase_M61 PF05299.12 EKX51387.1 - 0.066 13.6 0.7 0.12 12.8 0.7 1.4 1 0 0 1 1 1 0 M61 glycyl aminopeptidase BLOC1_2 PF10046.9 EKX51389.1 - 0.069 13.5 0.5 0.21 11.9 0.1 1.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IMD PF08397.11 EKX51389.1 - 0.2 11.0 2.8 1.8 7.9 0.3 2.1 2 0 0 2 2 2 0 IRSp53/MIM homology domain DMAP_binding PF06464.11 EKX51390.1 - 0.079 13.8 4.7 4.8 8.0 2.0 2.5 2 0 0 2 2 2 0 DMAP1-binding Domain DUF3528 PF12045.8 EKX51390.1 - 0.14 12.7 5.2 4.1 8.0 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3528) DUF4523 PF15023.6 EKX51390.1 - 0.25 11.2 5.2 0.18 11.6 2.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF4523) Mito_carr PF00153.27 EKX51391.1 - 2.6e-32 110.6 0.2 1.3e-19 69.9 0.0 2.7 2 1 0 2 2 2 2 Mitochondrial carrier protein Autophagy_N PF03986.13 EKX51392.1 - 7e-43 145.9 0.8 1e-42 145.3 0.8 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 EKX51392.1 - 1.1e-19 70.8 0.6 2.1e-19 69.8 0.6 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 EKX51392.1 - 5.9e-15 54.5 2.3 1.2e-14 53.5 2.3 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal MobC PF05713.11 EKX51393.1 - 0.49 10.9 4.7 3.2 8.3 0.3 4.6 3 0 0 3 3 3 0 Bacterial mobilisation protein (MobC) dCMP_cyt_deam_1 PF00383.23 EKX51394.1 - 5.5e-21 74.3 0.0 7e-21 74.0 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EKX51394.1 - 1.2e-12 47.8 0.0 1.4e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase Inv-AAD PF18785.1 EKX51394.1 - 0.0019 18.0 0.1 0.0047 16.8 0.1 1.7 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase APOBEC_N PF08210.11 EKX51394.1 - 0.18 11.7 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain DHC_N1 PF08385.12 EKX51395.1 - 2.6e-121 406.0 18.1 2.6e-121 406.0 18.1 6.3 4 2 0 5 5 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 EKX51395.1 - 1.5e-64 218.6 11.0 1.5e-64 218.6 11.0 5.1 5 1 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 EKX51395.1 - 5.7e-30 104.4 0.7 2.2e-29 102.5 0.7 2.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 EKX51395.1 - 5.6e-24 84.9 0.6 1.8e-23 83.3 0.6 1.9 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EKX51395.1 - 2.2e-21 76.0 0.1 2.2e-21 76.0 0.1 4.4 5 1 0 5 5 5 1 ATP-binding dynein motor region AAA_7 PF12775.7 EKX51395.1 - 4.9e-21 75.1 0.0 3e-17 62.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EKX51395.1 - 1.9e-18 66.8 0.0 9.3e-18 64.6 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EKX51395.1 - 8.3e-17 61.4 0.0 3.5e-16 59.4 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_8 PF12780.7 EKX51395.1 - 2.5e-09 36.8 14.7 3.5e-08 33.1 10.8 3.3 2 1 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_AAA_lid PF17852.1 EKX51395.1 - 5.6e-05 23.2 0.7 0.00053 20.1 0.1 3.2 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 EKX51395.1 - 0.00022 20.3 0.8 0.00046 19.3 0.8 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_22 PF13401.6 EKX51395.1 - 0.001 19.3 0.2 3.8 7.8 0.0 4.5 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EKX51395.1 - 0.0012 19.2 0.1 0.48 10.8 0.0 3.9 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.6 EKX51395.1 - 0.015 15.6 0.3 6.6 7.1 0.0 3.8 3 0 0 3 3 2 0 AAA ATPase domain Sigma54_activat PF00158.26 EKX51395.1 - 0.017 14.8 0.0 0.25 11.0 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 EKX51395.1 - 0.028 14.2 0.0 0.53 10.0 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein Takusan PF04822.13 EKX51395.1 - 0.092 12.6 3.9 0.081 12.8 0.1 3.2 3 0 0 3 3 1 0 Takusan DUF2540 PF10802.8 EKX51395.1 - 8.2 6.6 8.3 0.64 10.1 0.9 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2540) Glyco_hydro_5_C PF18564.1 EKX51396.1 - 0.059 13.9 0.1 0.3 11.7 0.1 2.2 1 0 0 1 1 1 0 Glycoside hydrolase family 5 C-terminal domain 2_5_RNA_ligase2 PF13563.6 EKX51397.1 - 8.8e-10 38.7 0.0 2.3e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 EKX51397.1 - 5e-06 26.6 0.0 0.18 12.0 0.0 3.6 3 0 0 3 3 3 2 LigT like Phosphoesterase AKAP7_NLS PF10469.9 EKX51397.1 - 0.00012 22.1 0.0 0.00032 20.7 0.0 1.8 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain DUF465 PF04325.13 EKX51397.1 - 0.001 19.0 5.9 0.0011 18.9 3.2 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF465) Fib_alpha PF08702.10 EKX51397.1 - 0.022 15.0 2.5 0.022 15.0 2.5 2.3 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Nup54 PF13874.6 EKX51397.1 - 0.031 14.4 0.4 0.031 14.4 0.4 2.0 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DivIC PF04977.15 EKX51397.1 - 0.045 13.5 3.1 1.5 8.7 0.3 2.9 2 0 0 2 2 2 0 Septum formation initiator DUF3287 PF11690.8 EKX51397.1 - 0.074 12.8 3.9 4.5 7.0 0.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3287) GIT_CC PF16559.5 EKX51397.1 - 0.24 11.3 1.9 25 4.8 0.1 2.8 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor TMF_TATA_bd PF12325.8 EKX51397.1 - 0.73 10.1 18.3 0.049 13.8 2.4 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding GreA_GreB_N PF03449.15 EKX51397.1 - 0.76 10.0 6.7 8.9 6.6 2.3 3.3 2 1 0 2 2 2 0 Transcription elongation factor, N-terminal SOGA PF11365.8 EKX51397.1 - 3.5 8.8 9.0 2.2 9.5 1.8 3.4 3 0 0 3 3 3 0 Protein SOGA Methyltransf_23 PF13489.6 EKX51398.1 - 4e-16 59.3 0.0 5e-16 59.0 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX51398.1 - 7.3e-13 49.0 0.0 1.4e-12 48.1 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX51398.1 - 8.6e-13 48.4 0.0 1.1e-12 48.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX51398.1 - 7.6e-12 45.8 0.0 1.6e-11 44.7 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX51398.1 - 4.6e-10 40.1 0.0 6.4e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EKX51398.1 - 7.8e-07 28.9 0.0 9.5e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_9 PF08003.11 EKX51398.1 - 1.8e-05 23.8 0.0 3.3e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 EKX51398.1 - 0.00011 22.3 0.0 0.00013 22.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EKX51398.1 - 0.0012 18.4 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 EKX51398.1 - 0.0096 15.0 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase CheR PF01739.18 EKX51398.1 - 0.013 15.0 0.1 5.3 6.5 0.0 2.4 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain AdoMet_MTase PF07757.13 EKX51398.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.5 1 1 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase PDEase_I PF00233.19 EKX51399.1 - 1e-69 234.9 0.1 1.3e-69 234.6 0.1 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF5519 PF17648.1 EKX51399.1 - 0.07 13.0 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5519) 2OG-FeII_Oxy_2 PF13532.6 EKX51400.1 - 5e-12 46.4 0.0 7.4e-12 45.9 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily VRR_NUC PF08774.11 EKX51401.1 - 2.8e-22 78.9 0.0 5.5e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 VRR-NUC domain Glutaredoxin2_C PF04399.13 EKX51401.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Sporozoite_P67 PF05642.11 EKX51401.1 - 1.4 6.9 9.1 2.2 6.3 9.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Keratin_2_head PF16208.5 EKX51401.1 - 5.8 7.0 28.0 12 6.1 28.0 1.4 1 0 0 1 1 1 0 Keratin type II head PP2C PF00481.21 EKX51403.1 - 9.3e-32 110.7 0.0 1.3e-31 110.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EKX51403.1 - 0.0068 16.1 0.0 0.05 13.2 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EKX51403.1 - 0.01 15.8 0.0 0.085 12.8 0.0 2.1 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) FAIM1 PF06905.13 EKX51403.1 - 0.052 13.2 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) Ion_trans PF00520.31 EKX51404.1 - 1.1e-17 64.1 20.8 1.8e-16 60.2 20.8 2.1 1 1 0 1 1 1 1 Ion transport protein EF-hand_1 PF00036.32 EKX51404.1 - 2e-09 36.3 5.4 0.0054 16.2 0.0 5.0 5 0 0 5 5 5 2 EF hand EF-hand_5 PF13202.6 EKX51404.1 - 1.1e-08 34.1 4.8 0.0035 16.8 0.0 4.6 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 EKX51404.1 - 3.7e-08 32.7 0.6 0.033 14.1 0.1 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 EKX51404.1 - 1.6e-07 31.7 4.4 0.0085 16.5 1.5 4.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 EKX51404.1 - 0.00099 18.9 3.4 0.68 9.8 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain pair DUF4088 PF13317.6 EKX51404.1 - 0.038 13.6 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) PKD_channel PF08016.12 EKX51404.1 - 0.054 12.2 11.9 0.021 13.5 9.2 1.6 1 1 1 2 2 2 0 Polycystin cation channel DUF1980 PF09323.10 EKX51404.1 - 8.1 6.3 6.2 1.7 8.5 1.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) CBFD_NFYB_HMF PF00808.23 EKX51405.1 - 2e-16 60.0 0.2 2.4e-16 59.8 0.2 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EKX51405.1 - 0.00056 20.3 0.2 0.0006 20.2 0.2 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 EKX51405.1 - 0.0025 18.1 0.1 0.0026 18.0 0.1 1.1 1 0 0 1 1 1 1 CENP-S associating Centromere protein X TAFII28 PF04719.14 EKX51405.1 - 0.0025 17.9 0.5 0.0029 17.7 0.5 1.1 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Helicase_C PF00271.31 EKX51406.1 - 1.8e-05 25.1 0.0 2.2e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Nod1 PF17114.5 EKX51408.1 - 0.033 14.4 0.6 0.065 13.4 0.6 1.5 1 1 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 DUF2408 PF10303.9 EKX51408.1 - 0.048 14.2 0.2 0.17 12.5 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) TINF2_N PF14973.6 EKX51408.1 - 0.1 12.9 0.7 0.29 11.5 0.3 1.9 1 1 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus DUF5503 PF17607.2 EKX51408.1 - 0.11 12.8 0.6 0.29 11.5 0.6 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5503) FA_desaturase PF00487.24 EKX51409.1 - 3.7e-25 89.2 8.3 5.1e-25 88.8 8.3 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Hydrolase_4 PF12146.8 EKX51410.1 - 3.3e-11 42.9 0.3 4.4e-11 42.5 0.3 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EKX51410.1 - 3.5e-10 39.9 0.1 5.2e-10 39.4 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EKX51410.1 - 4.5e-10 40.5 3.0 5.5e-10 40.2 3.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 EKX51410.1 - 0.00027 20.6 0.0 0.00036 20.2 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Palm_thioest PF02089.15 EKX51410.1 - 0.0011 18.9 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Thioesterase PF00975.20 EKX51410.1 - 0.0025 17.9 0.2 0.0047 17.1 0.2 1.5 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S10 PF00450.22 EKX51410.1 - 0.064 12.6 0.0 0.66 9.3 0.0 1.9 2 0 0 2 2 2 0 Serine carboxypeptidase Topo-VIb_trans PF09239.11 EKX51411.1 - 2.5e-46 157.4 0.0 5.1e-46 156.4 0.0 1.5 1 0 0 1 1 1 1 Topoisomerase VI B subunit, transducer HATPase_c PF02518.26 EKX51411.1 - 7.2e-08 32.9 0.0 2e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EKX51411.1 - 3.2e-06 27.0 0.8 4.8e-05 23.2 0.8 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WAC_Acf1_DNA_bd PF10537.9 EKX51411.1 - 0.1 13.1 1.8 2.9 8.5 0.1 3.0 2 1 1 3 3 3 0 ATP-utilising chromatin assembly and remodelling N-terminal Xpo1 PF08389.12 EKX51411.1 - 0.45 10.6 1.9 0.53 10.3 0.2 1.9 2 0 0 2 2 2 0 Exportin 1-like protein ATP-synt_ab PF00006.25 EKX51412.1 - 2.7e-20 73.0 0.2 1.4e-15 57.6 0.1 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EKX51412.1 - 0.0012 19.1 0.0 0.0079 16.5 0.0 2.4 1 1 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain IstB_IS21 PF01695.17 EKX51412.1 - 0.047 13.4 0.2 2.4 7.8 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein TetR_C_31 PF17940.1 EKX51412.1 - 0.077 13.2 0.1 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain MerR-DNA-bind PF09278.11 EKX51412.1 - 0.58 10.7 3.1 23 5.6 0.7 2.6 2 0 0 2 2 2 0 MerR, DNA binding rRNA_processing PF08524.11 EKX51413.1 - 8.4e-05 22.6 0.8 8.4e-05 22.6 0.8 3.1 3 0 0 3 3 3 2 rRNA processing Fmp27_SW PF10305.9 EKX51413.1 - 0.034 14.8 3.1 4 8.2 0.1 2.7 2 1 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF4519 PF15012.6 EKX51413.1 - 0.056 13.6 0.9 0.056 13.6 0.9 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4519) RCC1 PF00415.18 EKX51414.1 - 3.5e-35 120.4 18.1 3.8e-10 40.2 0.5 5.1 5 2 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX51414.1 - 9.6e-21 73.1 24.4 6.7e-06 25.8 1.1 5.8 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat LRR_4 PF12799.7 EKX51415.1 - 2.3e-09 37.4 6.5 6.1e-05 23.3 0.6 3.6 2 2 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX51415.1 - 1.7e-06 27.7 19.5 0.00021 21.0 2.1 3.9 1 1 3 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 EKX51415.1 - 0.069 13.7 10.0 78 4.4 0.1 6.0 6 0 0 6 6 6 0 Leucine Rich Repeat Laminin_G_3 PF13385.6 EKX51416.1 - 3.6e-06 27.2 0.0 7.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily NodZ PF05830.11 EKX51416.1 - 6.6e-06 25.2 0.0 2.3e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Nodulation protein Z (NodZ) EGF_Tenascin PF18720.1 EKX51416.1 - 0.36 10.9 7.9 1 9.5 7.9 1.8 1 0 0 1 1 1 0 Tenascin EGF domain EGF_2 PF07974.13 EKX51416.1 - 0.43 11.0 11.2 0.067 13.6 6.7 2.0 2 0 0 2 2 2 0 EGF-like domain SET PF00856.28 EKX51418.1 - 1.8e-10 41.5 0.0 9.4e-10 39.1 0.0 2.0 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 EKX51418.1 - 0.00052 20.7 0.2 0.0015 19.2 0.0 1.9 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding Oxysterol_BP PF01237.18 EKX51419.1 - 1.3e-54 185.5 6.0 1.1e-52 179.1 6.0 2.2 1 1 0 1 1 1 1 Oxysterol-binding protein Ank_2 PF12796.7 EKX51419.1 - 2.1e-13 50.7 0.3 6e-07 30.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX51419.1 - 3.3e-08 33.2 0.2 0.44 11.3 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EKX51419.1 - 8.6e-07 29.4 2.0 0.005 17.4 0.4 3.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX51419.1 - 1.3e-05 25.3 0.2 0.21 12.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX51419.1 - 1.7e-05 25.0 0.5 1.5 9.4 0.2 3.7 3 0 0 3 3 3 2 Ankyrin repeat TPR_12 PF13424.6 EKX51420.1 - 4e-52 174.4 38.8 3.6e-16 59.2 3.0 7.6 5 2 4 9 9 8 6 Tetratricopeptide repeat TPR_10 PF13374.6 EKX51420.1 - 1.4e-47 158.3 14.1 1.8e-09 37.2 0.1 8.3 7 1 1 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 EKX51420.1 - 1.9e-21 74.4 24.4 5.5e-06 26.1 0.8 8.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 EKX51420.1 - 1.4e-17 62.7 18.9 1.6e-05 24.5 0.5 7.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX51420.1 - 2.3e-13 50.3 19.4 3.3e-08 33.3 7.7 3.5 2 1 1 3 3 3 2 MalT-like TPR region TPR_7 PF13176.6 EKX51420.1 - 1.2e-12 46.9 23.0 0.0015 18.4 0.2 8.4 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 EKX51420.1 - 1.6e-11 43.4 20.4 0.0025 17.9 0.5 7.7 9 0 0 9 9 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 EKX51420.1 - 2e-09 37.9 32.2 0.00043 20.9 1.1 7.4 7 2 1 8 8 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 EKX51420.1 - 5.2e-07 29.6 6.7 0.7 10.4 0.0 6.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX51420.1 - 2.4e-06 28.0 22.8 0.14 12.6 2.7 6.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX51420.1 - 4.1e-06 26.4 9.8 0.27 10.9 0.2 5.7 5 0 0 5 5 5 2 TPR repeat TPR_4 PF07721.14 EKX51420.1 - 2.6e-05 24.4 14.2 5.6 7.9 0.1 7.7 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX51420.1 - 0.00046 20.8 33.4 0.12 13.3 0.2 9.0 11 0 0 11 11 8 1 Tetratricopeptide repeat SNAP PF14938.6 EKX51420.1 - 0.0014 18.1 6.4 0.11 11.9 3.7 2.8 1 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_3 PF07720.12 EKX51420.1 - 0.0029 17.6 2.7 14 5.8 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF627 PF04781.12 EKX51420.1 - 0.0034 17.4 7.0 0.24 11.4 0.4 4.0 3 1 1 4 4 4 1 Protein of unknown function (DUF627) ANAPC3 PF12895.7 EKX51420.1 - 0.023 14.9 13.1 0.31 11.3 0.3 5.3 4 2 0 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 EKX51420.1 - 0.036 13.5 0.2 0.036 13.5 0.2 4.5 5 0 0 5 5 4 0 SHNi-TPR GlcNAc_2-epim PF07221.11 EKX51420.1 - 0.051 12.8 0.6 0.097 11.9 0.3 1.5 1 1 0 1 1 1 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) MAS20 PF02064.15 EKX51420.1 - 0.13 12.4 1.1 2.7 8.1 1.0 2.8 1 1 0 1 1 1 0 MAS20 protein import receptor DUF5113 PF17140.4 EKX51420.1 - 0.13 12.1 1.1 78 3.0 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF5113) Peptidase_S46 PF10459.9 EKX51420.1 - 0.31 9.6 3.1 3.7 6.1 2.7 2.1 2 0 0 2 2 2 0 Peptidase S46 Fis1_TPR_C PF14853.6 EKX51420.1 - 0.51 10.4 3.8 1.6 8.9 0.0 3.3 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 EKX51420.1 - 0.6 10.2 23.0 1.4 9.1 0.2 6.7 5 2 2 7 7 7 0 MIT (microtubule interacting and transport) domain ANAPC5 PF12862.7 EKX51420.1 - 0.97 9.5 4.8 5.1 7.2 0.4 3.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 5 DUF2802 PF10975.8 EKX51420.1 - 4.4 7.5 10.3 8.8 6.5 0.1 4.2 4 0 0 4 4 3 0 Protein of unknown function (DUF2802) DUF1771 PF08590.10 EKX51420.1 - 4.9 7.6 8.4 36 4.8 0.4 4.7 5 1 1 6 6 5 0 Domain of unknown function (DUF1771) FliS PF02561.14 EKX51420.1 - 5.8 7.2 6.6 4.3 7.6 2.1 2.9 2 2 0 2 2 2 0 Flagellar protein FliS SMBP PF16785.5 EKX51420.1 - 7.4 6.8 14.6 1.4 9.2 0.3 3.8 2 1 2 4 4 4 0 Small metal-binding protein Vta1_C PF18097.1 EKX51420.1 - 8.1 6.2 7.1 15 5.4 0.1 3.7 4 0 0 4 4 4 0 Vta1 C-terminal domain CS PF04969.16 EKX51422.1 - 4.7e-05 24.3 0.0 0.00011 23.1 0.0 1.6 2 0 0 2 2 2 1 CS domain Phycobilisome PF00502.19 EKX51423.1 - 1.4e-20 73.8 0.0 1.7e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Phycobilisome protein Kinesin PF00225.23 EKX51424.1 - 4.8e-16 58.6 0.0 5.8e-16 58.3 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX51424.1 - 1.7e-09 37.7 0.0 4.3e-09 36.5 0.0 1.6 1 1 0 1 1 1 1 Microtubule binding MFS_1 PF07690.16 EKX51425.1 - 1.9e-14 53.3 53.7 3.2e-11 42.8 24.0 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Otopetrin PF03189.13 EKX51425.1 - 0.058 12.2 0.5 0.11 11.4 0.0 1.6 2 0 0 2 2 2 0 Otopetrin DUF1118 PF06549.12 EKX51425.1 - 2 8.8 7.2 4.1 7.7 6.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1118) Pkinase PF00069.25 EKX51426.1 - 3.2e-27 95.6 0.0 4.2e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX51426.1 - 2.4e-11 43.4 0.0 3e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX51426.1 - 0.0056 16.6 1.2 0.0089 16.0 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX51426.1 - 0.012 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EKX51426.1 - 0.039 13.5 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family 7TM_GPCR_Str PF10326.9 EKX51428.1 - 0.0097 15.3 5.7 0.0097 15.3 5.7 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str NIF PF03031.18 EKX51429.1 - 1.7e-46 157.8 0.2 3.9e-46 156.7 0.2 1.5 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase MbeB_N PF04837.12 EKX51430.1 - 3.2 8.2 6.5 29 5.1 1.7 3.0 2 1 0 2 2 2 0 MbeB-like, N-term conserved region MMS1_N PF10433.9 EKX51431.1 - 3.4e-32 111.7 0.1 5.2e-32 111.1 0.1 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EKX51431.1 - 1.1e-10 41.3 0.5 5.8e-06 25.9 0.0 3.6 4 0 0 4 4 4 3 CPSF A subunit region cNMP_binding PF00027.29 EKX51432.1 - 4e-10 39.6 0.0 7.5e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 EKX51432.1 - 8.1e-09 35.1 9.5 1.6e-08 34.1 9.5 1.4 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX51432.1 - 7.5e-06 25.8 7.2 7.5e-06 25.8 7.2 2.4 2 1 0 2 2 2 1 Ion channel Syntaxin PF00804.25 EKX51433.1 - 0.09 12.4 0.1 0.09 12.4 0.1 1.6 2 0 0 2 2 2 0 Syntaxin FH2 PF02181.23 EKX51434.1 - 3.2e-88 296.4 5.7 3.2e-88 296.4 5.7 1.5 2 0 0 2 2 2 1 Formin Homology 2 Domain DALR_1 PF05746.15 EKX51434.1 - 0.3 11.3 2.7 2.2 8.5 0.4 2.6 1 1 1 2 2 2 0 DALR anticodon binding domain L51_S25_CI-B8 PF05047.16 EKX51435.1 - 0.042 13.8 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain zf-C3HC4_5 PF17121.5 EKX51435.1 - 0.2 11.6 0.0 16 5.4 0.0 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FAD_binding_7 PF03441.14 EKX51436.1 - 2.1e-53 180.8 1.1 3.1e-53 180.3 1.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EKX51436.1 - 8.8e-38 129.9 0.0 1.4e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 DNA photolyase TPR_1 PF00515.28 EKX51437.1 - 1.1e-32 110.5 0.9 9.4e-06 25.2 1.6 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 EKX51437.1 - 7.9e-29 97.4 1.3 4.1e-05 23.4 1.9 7.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 EKX51437.1 - 2e-22 77.5 0.9 6.3e-05 22.9 0.5 6.9 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 EKX51437.1 - 5.1e-19 67.7 3.2 3.4e-06 26.6 0.1 6.4 3 1 3 6 6 6 5 TPR repeat TPR_16 PF13432.6 EKX51437.1 - 2.3e-15 56.9 4.9 3.3e-05 24.4 1.7 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 EKX51437.1 - 4e-13 49.3 4.6 0.0012 19.0 0.9 6.0 2 1 4 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 EKX51437.1 - 1.9e-11 44.1 5.2 0.00011 22.4 0.5 4.0 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX51437.1 - 1.9e-11 43.1 0.0 0.0015 18.4 0.1 5.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX51437.1 - 5.3e-11 42.4 10.8 0.0031 18.2 0.1 6.2 3 2 3 6 6 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 EKX51437.1 - 6.6e-10 39.3 6.5 3.6e-05 24.2 0.4 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX51437.1 - 8.9e-10 38.3 2.4 0.0029 17.9 0.4 5.7 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX51437.1 - 3.4e-06 27.3 3.7 4.4 8.2 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX51437.1 - 4.7e-05 23.5 1.1 0.34 11.1 0.0 3.1 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EKX51437.1 - 0.00049 19.9 8.1 0.14 12.0 0.9 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat BTAD PF03704.17 EKX51437.1 - 0.00072 20.0 1.3 0.13 12.7 0.2 3.3 3 0 0 3 3 3 1 Bacterial transcriptional activator domain TPR_15 PF13429.6 EKX51437.1 - 0.046 12.9 0.9 1.7 7.8 0.0 2.8 2 1 0 3 3 3 0 Tetratricopeptide repeat FAT PF02259.23 EKX51437.1 - 0.059 12.6 0.4 0.41 9.8 0.1 2.2 2 1 0 2 2 2 0 FAT domain SHNi-TPR PF10516.9 EKX51437.1 - 0.46 10.0 2.0 4 7.0 0.0 3.0 3 0 0 3 3 3 0 SHNi-TPR Arm PF00514.23 EKX51438.1 - 4.6e-06 26.5 8.6 0.072 13.2 0.0 5.6 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat DUF3654 PF12376.8 EKX51438.1 - 0.054 13.7 0.4 0.19 11.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3654) Kringle PF00051.18 EKX51439.1 - 1e-19 70.6 1.0 1.1e-19 70.5 1.0 1.0 1 0 0 1 1 1 1 Kringle domain Ribosomal_L30_N PF08079.12 EKX51440.1 - 3e-20 72.2 12.8 3e-20 72.2 12.8 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 EKX51440.1 - 1.4e-16 60.1 1.7 1.4e-16 60.1 1.7 1.9 2 1 0 2 2 2 1 Ribosomal protein L30p/L7e VID27_N PF17748.1 EKX51440.1 - 0.077 12.8 0.2 0.16 11.8 0.0 1.6 2 0 0 2 2 2 0 VID27 N-terminal region TPR_1 PF00515.28 EKX51441.1 - 1.5e-07 30.9 3.9 0.05 13.4 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX51441.1 - 2.3e-05 24.6 12.7 2.6e-05 24.4 0.2 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat IQ PF00612.27 EKX51441.1 - 0.00024 20.6 1.2 0.00075 19.1 1.2 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif TPR_2 PF07719.17 EKX51441.1 - 0.00072 19.5 5.0 3.8 7.9 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX51441.1 - 0.12 12.5 2.3 5.8 7.2 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX51441.1 - 1.2 9.1 6.1 2.8 7.9 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Laminin_G_3 PF13385.6 EKX51443.1 - 7e-07 29.5 4.8 1.9e-05 24.8 4.8 2.6 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily LysM PF01476.20 EKX51443.1 - 1.6e-06 28.0 0.1 0.0049 16.9 0.0 2.9 3 0 0 3 3 3 2 LysM domain PRMT5_TIM PF17285.2 EKX51443.1 - 0.13 11.4 0.0 0.28 10.4 0.0 1.5 1 0 0 1 1 1 0 PRMT5 TIM barrel domain PTN_MK_N PF05196.13 EKX51445.1 - 0.0094 16.1 0.2 0.17 12.1 0.1 2.2 2 0 0 2 2 2 1 PTN/MK heparin-binding protein family, N-terminal domain Pkinase PF00069.25 EKX51446.1 - 2e-35 122.5 0.0 3e-35 121.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX51446.1 - 6.3e-23 81.4 0.0 1.7e-21 76.7 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX51446.1 - 0.00054 19.4 0.2 0.0024 17.2 0.1 2.1 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EKX51446.1 - 0.078 12.6 0.1 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Peptidase_M18 PF02127.15 EKX51447.1 - 4.3e-156 520.0 0.0 4.9e-156 519.9 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EKX51447.1 - 1.9e-10 40.3 0.1 1.2e-06 27.8 0.2 2.5 2 1 0 2 2 2 2 M42 glutamyl aminopeptidase Xpo1 PF08389.12 EKX51448.1 - 0.00093 19.3 0.7 0.00093 19.3 0.7 3.6 5 0 0 5 5 5 1 Exportin 1-like protein Flavokinase PF01687.17 EKX51448.1 - 0.0084 16.4 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 Riboflavin kinase Importin_rep_3 PF18806.1 EKX51448.1 - 0.012 15.7 0.2 1.6 8.9 0.0 2.9 2 0 0 2 2 2 0 Importin 13 repeat Aldedh PF00171.22 EKX51449.1 - 0.0065 15.0 0.0 0.0093 14.5 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family B12-binding PF02310.19 EKX51449.1 - 0.19 11.8 0.1 4.9 7.2 0.0 2.7 3 0 0 3 3 3 0 B12 binding domain Ephrin_rec_like PF07699.13 EKX51450.1 - 3.1e-09 36.4 10.2 3.1e-09 36.4 10.2 5.6 3 1 2 5 5 5 3 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX51450.1 - 5.8e-08 33.0 52.0 8.3e-06 26.1 6.8 6.3 4 2 3 7 7 7 6 TNFR/NGFR cysteine-rich region VirDNA-topo-I_N PF09266.10 EKX51450.1 - 0.044 14.0 0.0 0.49 10.6 0.0 2.2 1 1 1 2 2 2 0 Viral DNA topoisomerase I, N-terminal PDZ PF00595.24 EKX51451.1 - 1.1e-05 25.7 0.1 2.4e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX51451.1 - 0.00017 21.4 0.3 0.00036 20.3 0.3 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX51451.1 - 0.00061 20.1 1.4 0.0017 18.6 0.2 2.4 2 0 0 2 2 2 1 PDZ domain DUF898 PF05987.13 EKX51451.1 - 0.0091 15.1 3.2 1.2 8.1 0.1 3.1 2 1 1 3 3 3 2 Bacterial protein of unknown function (DUF898) PH PF00169.29 EKX51451.1 - 0.02 15.4 3.6 0.9 10.1 0.1 3.1 3 0 0 3 3 3 0 PH domain Mrr_N PF14338.6 EKX51451.1 - 2.3 8.4 4.5 1.1 9.4 0.3 2.6 3 0 0 3 3 3 0 Mrr N-terminal domain Mucin PF01456.17 EKX51451.1 - 8.2 6.4 27.1 19 5.2 27.1 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Malic_M PF03949.15 EKX51452.1 - 1.7e-33 116.0 0.0 2.7e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EKX51452.1 - 1.5e-11 44.4 0.0 2.7e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 EKX51453.1 - 2.8e-17 62.8 0.0 3.7e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain Ion_trans PF00520.31 EKX51454.1 - 5.7e-31 107.6 22.0 4.3e-30 104.7 22.0 2.0 1 1 0 1 1 1 1 Ion transport protein EF-hand_1 PF00036.32 EKX51454.1 - 5.5e-15 53.7 4.1 0.0015 17.9 0.1 4.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EKX51454.1 - 1.6e-13 49.4 0.7 0.0043 16.9 0.0 4.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EKX51454.1 - 1.8e-12 46.1 9.1 0.00063 19.1 0.0 4.0 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EKX51454.1 - 4.2e-12 45.7 0.9 0.0032 17.3 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_7 PF13499.6 EKX51454.1 - 6.7e-12 45.7 4.9 4.9e-08 33.3 0.2 3.8 3 1 1 4 4 4 3 EF-hand domain pair PKD_channel PF08016.12 EKX51454.1 - 9.8e-06 24.5 11.3 9.8e-06 24.5 11.3 2.0 1 1 1 2 2 2 1 Polycystin cation channel Trypan_PARP PF05887.11 EKX51454.1 - 0.0038 17.2 7.0 0.0073 16.3 7.0 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) EF-hand_4 PF12763.7 EKX51454.1 - 0.0098 15.8 0.2 0.63 10.0 0.0 3.2 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand Neisseria_TspB PF05616.13 EKX51454.1 - 0.71 8.3 7.8 1.1 7.6 7.8 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF4834 PF16118.5 EKX51454.1 - 1.4 9.9 4.9 8.5 7.4 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) DUF4199 PF13858.6 EKX51454.1 - 3.5 8.0 11.4 0.77 10.1 2.7 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF4199) DHHC PF01529.20 EKX51454.1 - 6 7.0 6.4 0.92 9.6 0.5 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase PDZ_6 PF17820.1 EKX51455.1 - 1.3e-05 24.9 1.8 2e-05 24.3 0.0 2.3 3 0 0 3 3 3 1 PDZ domain PDZ PF00595.24 EKX51455.1 - 0.00098 19.4 0.1 0.0028 18.0 0.1 1.7 1 0 0 1 1 1 1 PDZ domain Trypan_PARP PF05887.11 EKX51455.1 - 1.1 9.2 13.6 1.9 8.4 13.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) IQ PF00612.27 EKX51455.1 - 2 8.4 54.9 1.6 8.7 0.1 12.5 14 0 0 14 14 14 0 IQ calmodulin-binding motif PPP4R2 PF09184.11 EKX51455.1 - 2.4 7.7 14.1 4.7 6.7 14.1 1.4 1 0 0 1 1 1 0 PPP4R2 VF530 PF09905.9 EKX51457.1 - 1.2e-19 70.2 0.0 2.5e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 DNA-binding protein VF530 SRP-alpha_N PF04086.13 EKX51457.1 - 0.25 11.3 3.4 0.43 10.5 3.4 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Collagen PF01391.18 EKX51458.1 - 8.2e-42 140.8 158.8 3.9e-10 39.3 29.3 6.2 3 1 4 7 7 7 6 Collagen triple helix repeat (20 copies) Lectin_C PF00059.21 EKX51458.1 - 2e-10 41.4 0.2 3e-10 40.8 0.2 1.3 1 0 0 1 1 1 1 Lectin C-type domain YabA PF06156.13 EKX51458.1 - 0.052 14.2 0.2 0.12 13.0 0.0 1.6 2 0 0 2 2 2 0 Initiation control protein YabA GAS PF13851.6 EKX51458.1 - 0.071 12.5 6.2 0.099 12.0 6.2 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CENP-B_dimeris PF09026.10 EKX51458.1 - 0.17 12.3 0.1 0.27 11.6 0.1 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Prok-TraM PF09228.10 EKX51458.1 - 0.4 11.1 0.9 0.65 10.4 0.9 1.2 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM HIP1_clath_bdg PF16515.5 EKX51458.1 - 0.7 10.5 5.0 1.1 9.9 5.0 1.2 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 cNMP_binding PF00027.29 EKX51459.1 - 3.1e-11 43.2 0.2 1.9e-07 31.1 0.1 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain EF-hand_1 PF00036.32 EKX51460.1 - 1.9e-07 30.1 1.0 0.00026 20.3 0.4 3.5 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 EKX51460.1 - 7.5e-07 28.9 0.6 0.00012 21.8 0.2 3.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.6 EKX51460.1 - 1.4e-06 28.6 5.6 4.9e-06 26.9 3.4 2.6 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX51460.1 - 1.4e-05 24.7 1.1 0.0012 18.6 0.1 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 EKX51460.1 - 2.5e-05 23.6 1.6 0.00025 20.4 1.0 2.8 2 0 0 2 2 2 1 EF hand CorC_HlyC PF03471.17 EKX51460.1 - 0.061 13.3 0.0 0.75 9.9 0.0 2.4 2 1 0 2 2 2 0 Transporter associated domain SR-25 PF10500.9 EKX51461.1 - 0.011 15.3 16.3 0.011 15.3 16.3 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RNA_polI_A34 PF08208.11 EKX51461.1 - 0.019 15.1 18.0 0.019 15.1 18.0 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF4604 PF15377.6 EKX51461.1 - 0.11 13.0 29.7 0.93 9.9 2.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Vfa1 PF08432.10 EKX51461.1 - 0.18 12.2 38.1 0.12 12.7 19.6 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 AP3D1 PF06375.11 EKX51461.1 - 0.27 11.5 43.7 1.2 9.4 9.0 2.4 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Eapp_C PF10238.9 EKX51461.1 - 0.62 10.1 18.8 0.99 9.5 7.9 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein Spt20 PF12090.8 EKX51461.1 - 0.89 9.1 19.4 0.14 11.8 11.9 2.2 2 0 0 2 2 2 0 Spt20 family PRC2_HTH_1 PF18118.1 EKX51461.1 - 1.1 10.1 20.6 0.54 11.1 7.1 2.5 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain SpoIIP PF07454.11 EKX51461.1 - 1.6 8.2 20.0 0.53 9.7 8.3 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) CPSF100_C PF13299.6 EKX51461.1 - 1.7 8.8 18.6 1.4 9.1 6.2 2.4 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Rxt3 PF08642.10 EKX51461.1 - 2.1 9.1 11.0 9.5 7.0 4.9 2.4 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 GNAT_acetyltr_2 PF13718.6 EKX51461.1 - 2.2 7.6 15.3 0.98 8.8 3.8 2.2 2 0 0 2 2 2 0 GNAT acetyltransferase 2 BRF1 PF07741.13 EKX51461.1 - 2.9 8.3 31.6 0.73 10.2 13.6 2.6 3 0 0 3 3 2 0 Brf1-like TBP-binding domain GAGA_bind PF06217.12 EKX51461.1 - 3.3 7.9 25.2 1.9 8.7 12.1 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family Connexin PF00029.19 EKX51461.1 - 3.4 7.4 21.0 1.8 8.3 8.9 2.2 2 0 0 2 2 2 0 Connexin Coilin_N PF15862.5 EKX51461.1 - 3.9 7.3 33.0 0.64 9.8 14.3 2.5 2 0 0 2 2 2 0 Coilin N-terminus BORG_CEP PF14957.6 EKX51461.1 - 4.3 8.5 13.8 8.8 7.5 5.0 2.2 2 0 0 2 2 2 0 Cdc42 effector DDHD PF02862.17 EKX51461.1 - 4.7 7.3 20.2 0.011 15.9 4.6 2.1 1 1 1 2 2 2 0 DDHD domain RPA43_OB PF17875.1 EKX51461.1 - 4.8 7.8 14.1 3.3 8.3 4.4 2.4 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I LicD PF04991.13 EKX51461.1 - 6.4 6.8 19.7 0.8 9.8 9.4 2.1 2 0 0 2 2 2 0 LicD family RNA_pol_Rpc4 PF05132.14 EKX51461.1 - 7.8 6.9 25.2 0.26 11.7 8.8 2.6 3 0 0 3 3 3 0 RNA polymerase III RPC4 EIIBC-GUT_N PF03612.14 EKX51461.1 - 8.9 6.0 22.5 7.5 6.3 10.4 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus TRAP_alpha PF03896.16 EKX51461.1 - 9.9 5.3 11.3 0.88 8.7 1.9 2.2 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit SCO1-SenC PF02630.14 EKX51462.1 - 5.2e-48 162.4 0.0 5.3e-47 159.1 0.0 2.0 2 0 0 2 2 2 1 SCO1/SenC AhpC-TSA PF00578.21 EKX51462.1 - 8.2e-05 22.5 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EKX51462.1 - 0.0018 18.5 0.0 0.004 17.5 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Methyltransf_11 PF08241.12 EKX51463.1 - 8.2e-18 64.9 0.0 1.2e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX51463.1 - 6.4e-17 61.7 0.0 1.5e-15 57.2 0.0 2.0 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EKX51463.1 - 2e-16 60.5 0.0 3.4e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX51463.1 - 1.7e-12 47.4 0.0 2.2e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX51463.1 - 2.6e-07 31.3 0.0 4.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX51463.1 - 4.8e-05 23.3 0.0 0.00012 22.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 EKX51463.1 - 0.024 14.0 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_2 PF00891.18 EKX51463.1 - 0.11 11.8 0.0 0.23 10.7 0.0 1.6 1 1 0 1 1 1 0 O-methyltransferase domain MTS PF05175.14 EKX51463.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.20 EKX51463.1 - 0.24 10.4 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase RPN2_C PF18004.1 EKX51464.1 - 3.6e-54 183.0 5.1 3.6e-54 183.0 5.1 2.1 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 EKX51464.1 - 1.5e-30 104.1 17.3 3.1e-09 36.8 0.0 7.7 8 0 0 8 8 8 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EKX51464.1 - 1.6e-17 63.6 3.6 5e-11 42.8 0.0 5.2 3 1 4 7 7 7 4 HEAT repeats Cnd1 PF12717.7 EKX51464.1 - 0.00015 21.8 0.5 0.02 14.9 0.0 3.0 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EKX51464.1 - 0.00022 21.7 0.1 3.9 8.1 0.1 4.4 3 1 2 5 5 5 3 HEAT-like repeat HEAT PF02985.22 EKX51464.1 - 0.02 15.1 5.2 0.99 9.8 0.1 4.7 5 0 0 5 5 5 0 HEAT repeat Mif2_N PF15624.6 EKX51464.1 - 0.039 14.6 2.8 0.089 13.5 2.8 1.5 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal DUF1702 PF08012.11 EKX51464.1 - 0.043 12.7 0.3 0.68 8.8 0.3 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1702) Clathrin_H_link PF13838.6 EKX51464.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Clathrin-H-link zinc_ribbon_4 PF13717.6 EKX51465.1 - 0.029 14.3 1.4 0.11 12.5 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Auto_anti-p27 PF06677.12 EKX51465.1 - 0.041 14.0 2.3 0.091 12.9 2.2 1.7 1 1 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) ADK_lid PF05191.14 EKX51465.1 - 0.23 11.4 1.4 6.6 6.8 0.0 3.1 3 0 0 3 3 3 0 Adenylate kinase, active site lid TGT PF01702.18 EKX51466.1 - 8.8e-107 357.3 0.0 1e-106 357.0 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Pkinase PF00069.25 EKX51468.1 - 7.9e-46 156.5 0.0 1.2e-44 152.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX51468.1 - 3.7e-24 85.4 1.4 1.9e-23 83.1 0.2 2.2 2 1 1 3 3 3 1 Protein tyrosine kinase APH PF01636.23 EKX51468.1 - 0.00096 19.1 0.1 0.0037 17.2 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EKX51468.1 - 0.0035 17.0 0.1 0.11 12.1 0.0 2.1 1 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EKX51468.1 - 0.031 13.7 0.2 0.05 12.9 0.2 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EKX51468.1 - 0.083 12.2 0.4 0.27 10.5 0.1 1.9 1 1 1 2 2 2 0 Kinase-like AAA_13 PF13166.6 EKX51469.1 - 0.014 14.1 10.7 0.024 13.3 10.7 1.4 1 0 0 1 1 1 0 AAA domain Microtub_bd PF16796.5 EKX51469.1 - 0.02 14.8 0.4 1.9 8.4 0.1 2.4 2 1 0 2 2 2 0 Microtubule binding ADSL_C PF10397.9 EKX51469.1 - 0.1 13.2 0.8 0.23 12.0 0.7 1.6 1 1 0 1 1 1 0 Adenylosuccinate lyase C-terminus Streptin-Immun PF11083.8 EKX51469.1 - 0.16 12.4 6.8 0.68 10.4 5.3 2.5 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein HU-CCDC81_bac_2 PF18175.1 EKX51469.1 - 0.25 11.2 3.0 1.7 8.6 0.1 3.0 3 0 0 3 3 3 0 CCDC81-like prokaryotic HU domain 2 UvrA_inter PF17760.1 EKX51469.1 - 0.27 11.3 4.5 0.2 11.7 1.2 2.1 1 1 1 2 2 2 0 UvrA interaction domain DUF4239 PF14023.6 EKX51469.1 - 0.34 10.6 4.4 0.49 10.1 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) LMBR1 PF04791.16 EKX51469.1 - 0.47 9.3 5.2 0.48 9.3 5.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF724 PF05266.14 EKX51469.1 - 0.65 9.8 16.8 0.46 10.3 13.2 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF724) DUF848 PF05852.11 EKX51469.1 - 1 9.5 12.8 0.078 13.1 1.8 2.4 2 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) DUF1664 PF07889.12 EKX51469.1 - 1.6 8.8 13.3 1.7 8.7 7.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 EKX51469.1 - 1.9 7.8 14.0 1e+02 2.1 13.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.8 EKX51469.1 - 2.8 8.2 15.0 0.83 9.9 10.8 2.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding BST2 PF16716.5 EKX51469.1 - 3.3 8.4 12.8 7.7 7.2 0.4 3.2 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 Noelin-1 PF12308.8 EKX51469.1 - 8.3 6.5 9.5 9.8 6.2 2.1 2.8 2 1 1 3 3 3 0 Neurogenesis glycoprotein DUF1690 PF07956.11 EKX51469.1 - 8.4 6.8 18.0 6 7.3 9.6 2.2 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) L31 PF09784.9 EKX51469.1 - 9.3 6.7 8.4 2.9 8.4 4.4 2.1 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L31 Cyclin PF08613.11 EKX51470.1 - 1.5e-23 83.9 0.0 1.8e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EKX51470.1 - 7.1e-06 25.8 0.0 1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EKX51471.1 - 1.1e-23 84.3 0.1 1.6e-23 83.8 0.1 1.3 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EKX51471.1 - 7.5e-06 25.7 0.0 1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Flu_B_M2 PF04772.12 EKX51472.1 - 0.12 12.6 2.0 2.4 8.4 0.3 3.5 4 0 0 4 4 4 0 Influenza B matrix protein 2 (BM2) PBP_like_2 PF12849.7 EKX51473.1 - 8.5e-32 110.9 0.4 1.1e-31 110.5 0.4 1.2 1 0 0 1 1 1 1 PBP superfamily domain TcA_RBD PF18518.1 EKX51473.1 - 0.0066 16.7 0.1 0.011 16.0 0.1 1.3 1 0 0 1 1 1 1 TcA receptor binding domain ssDBP_DBD PF18361.1 EKX51473.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Single stranded DNA-binding protein ss DNA binding domain PDZ_6 PF17820.1 EKX51474.1 - 0.00017 21.4 0.3 0.00045 20.0 0.1 1.8 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX51474.1 - 0.00029 21.1 0.0 0.00066 20.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX51474.1 - 0.00088 19.6 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 PDZ domain HALZ PF02183.18 EKX51474.1 - 0.0075 16.5 2.8 0.03 14.5 0.2 2.7 2 0 0 2 2 2 1 Homeobox associated leucine zipper DERM PF14704.6 EKX51475.1 - 1.6 9.2 6.2 4.2 7.9 1.5 2.5 1 1 1 2 2 2 0 Dermatopontin PPP1R35_C PF15503.6 EKX51475.1 - 2.4 7.9 8.3 0.15 11.9 1.5 2.2 2 1 0 2 2 2 0 Protein phosphatase 1 regulatory subunit 35 C-terminus Anoctamin PF04547.12 EKX51476.1 - 1.8e-62 211.6 15.7 2.7e-62 211.1 15.7 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel LysM PF01476.20 EKX51477.1 - 0.09 12.9 0.1 5.7 7.1 0.0 3.1 3 0 0 3 3 3 0 LysM domain Guanylate_cyc PF00211.20 EKX51479.1 - 7e-22 77.9 0.0 7.7e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Caps_synth_CapC PF14102.6 EKX51480.1 - 0.45 11.0 8.9 0.21 12.0 3.0 2.5 2 0 0 2 2 2 0 Capsule biosynthesis CapC Flg_hook PF02120.16 EKX51481.1 - 0.089 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK FIN1 PF17300.2 EKX51482.1 - 0.0051 16.4 0.7 0.029 13.9 0.3 2.3 2 0 0 2 2 2 1 Filaments in between nuclei protein-1 Phage_GP20 PF06810.11 EKX51482.1 - 4.5 7.1 6.6 10 5.9 5.3 2.1 2 1 0 2 2 2 0 Phage minor structural protein GP20 Branch PF02485.21 EKX51484.1 - 7.1e-27 94.5 0.2 7.1e-27 94.5 0.2 1.7 2 0 0 2 2 2 1 Core-2/I-Branching enzyme RRM_1 PF00076.22 EKX51485.1 - 4.2e-24 84.2 0.1 3.8e-11 42.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EKX51485.1 - 6.1e-10 38.8 0.0 0.00094 18.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EKX51485.1 - 1.7e-09 37.4 0.0 0.00011 22.0 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif PHM7_cyt PF14703.6 EKX51485.1 - 0.12 12.6 2.9 1.1 9.5 0.2 2.5 1 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Peptidase_S41_N PF11918.8 EKX51486.1 - 0.04 14.2 1.6 1.1 9.5 0.1 2.4 2 0 0 2 2 2 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP DUF4763 PF15960.5 EKX51487.1 - 0.00078 18.8 12.7 0.0097 15.2 2.3 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4763) DUF1664 PF07889.12 EKX51487.1 - 0.019 15.0 2.1 0.019 15.0 2.1 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) VP4_haemagglut PF00426.18 EKX51487.1 - 0.037 14.2 1.7 0.067 13.4 0.9 1.7 1 1 1 2 2 2 0 Outer Capsid protein VP4 (Hemagglutinin) Concanavalin-like domain Mating_N PF12731.7 EKX51487.1 - 0.094 12.8 2.0 17 5.6 0.0 3.4 4 1 1 5 5 5 0 Mating-type protein beta 1 DUF713 PF05218.14 EKX51487.1 - 0.15 11.8 16.0 0.09 12.5 9.1 3.3 2 1 3 5 5 5 0 Protein of unknown function (DUF713) ZnuA PF01297.17 EKX51487.1 - 0.2 11.1 4.2 0.14 11.5 1.8 2.0 1 1 0 2 2 2 0 Zinc-uptake complex component A periplasmic TMF_DNA_bd PF12329.8 EKX51487.1 - 0.21 11.6 13.6 0.35 10.9 5.0 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF16 PF01519.16 EKX51487.1 - 0.34 11.4 14.0 0.82 10.2 3.7 3.9 4 0 0 4 4 4 0 Protein of unknown function DUF16 MbeD_MobD PF04899.12 EKX51487.1 - 1.9 8.6 7.5 18 5.5 0.0 3.6 3 1 0 3 3 3 0 MbeD/MobD like Cortex-I_coil PF09304.10 EKX51487.1 - 2.3 8.5 9.9 0.92 9.8 5.2 2.5 2 0 0 2 2 2 0 Cortexillin I, coiled coil Noelin-1 PF12308.8 EKX51487.1 - 2.8 8.0 10.3 1.5 8.9 0.3 3.4 2 1 1 3 3 3 0 Neurogenesis glycoprotein DASH_Duo1 PF08651.10 EKX51487.1 - 7.1 6.5 15.6 0.63 9.9 1.2 3.9 4 1 1 5 5 5 0 DASH complex subunit Duo1 adh_short PF00106.25 EKX51489.1 - 9.1e-15 54.6 0.1 1.4e-14 54.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase PDZ_6 PF17820.1 EKX51489.1 - 2.1e-11 43.5 0.1 5.9e-11 42.0 0.1 1.8 2 0 0 2 2 2 1 PDZ domain adh_short_C2 PF13561.6 EKX51489.1 - 1e-10 41.6 0.0 1.5e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PDZ PF00595.24 EKX51489.1 - 1.6e-08 34.8 0.3 4.9e-08 33.2 0.1 1.9 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX51489.1 - 1.7e-08 34.7 0.0 3.7e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 PDZ domain KR PF08659.10 EKX51489.1 - 0.0018 18.2 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF5462 PF17547.2 EKX51489.1 - 0.049 13.0 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5462) GRASP55_65 PF04495.14 EKX51489.1 - 0.14 12.5 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Epimerase PF01370.21 EKX51489.1 - 0.16 11.4 0.0 0.34 10.3 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PX PF00787.24 EKX51490.1 - 1.1e-08 35.0 0.4 2.1e-08 34.1 0.4 1.4 1 0 0 1 1 1 1 PX domain MutL_C PF08676.11 EKX51491.1 - 1.1e-31 109.7 0.0 2.1e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 EKX51491.1 - 5.8e-28 96.9 0.0 1.1e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EKX51491.1 - 8.1e-13 48.4 0.0 1.7e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EKX51491.1 - 4.2e-06 27.2 0.0 1.1e-05 25.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SnAC PF14619.6 EKX51491.1 - 0.034 14.8 2.0 0.077 13.6 2.0 1.5 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex LEF-9 PF05094.12 EKX51491.1 - 0.11 11.0 0.1 7 5.1 0.0 2.2 2 0 0 2 2 2 0 Late expression factor 9 (LEF-9) DUF3106 PF11304.8 EKX51491.1 - 0.12 12.9 1.2 0.38 11.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) RrnaAD PF00398.20 EKX51492.1 - 1.8e-41 142.0 0.0 2.1e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 EKX51492.1 - 0.0013 18.3 0.0 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EKX51492.1 - 0.0018 18.9 0.0 0.0033 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EKX51492.1 - 0.0026 17.1 0.0 0.02 14.2 0.0 2.0 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_23 PF13489.6 EKX51492.1 - 0.015 15.1 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 EKX51492.1 - 0.023 14.3 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_28 PF02636.17 EKX51492.1 - 0.03 13.9 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF5615 PF18480.1 EKX51492.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) Methyltransf_32 PF13679.6 EKX51492.1 - 0.18 11.8 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Abhydrolase_2 PF02230.16 EKX51493.1 - 3.5e-16 59.7 0.0 5.8e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Acylphosphatase PF00708.18 EKX51493.1 - 1.7e-07 31.6 0.3 3.1e-07 30.7 0.3 1.5 1 0 0 1 1 1 1 Acylphosphatase Bro-N PF02498.17 EKX51493.1 - 0.014 16.1 0.1 0.12 13.1 0.0 2.2 2 0 0 2 2 2 0 BRO family, N-terminal domain GDH_N PF12466.8 EKX51495.1 - 0.022 15.0 0.8 0.042 14.1 0.1 1.8 2 0 0 2 2 2 0 Glutamate dehydrogenase N terminal Ribosomal_L35p PF01632.19 EKX51496.1 - 1.3e-15 57.6 7.9 2.5e-15 56.7 7.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L35 ORC6 PF05460.13 EKX51497.1 - 3.1 7.0 10.2 0.024 13.9 1.2 2.0 3 0 0 3 3 3 0 Origin recognition complex subunit 6 (ORC6) Ank_2 PF12796.7 EKX51499.1 - 3.2e-08 34.0 0.1 3.3e-05 24.4 0.0 2.8 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 EKX51499.1 - 4.9e-06 26.7 0.6 0.058 13.9 0.0 3.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EKX51499.1 - 8.5e-06 26.0 0.1 0.0066 16.7 0.1 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX51499.1 - 2.6e-05 24.7 0.0 0.46 11.1 0.0 3.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX51499.1 - 0.02 15.4 0.0 1.9 9.3 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeat DUF3731 PF12531.8 EKX51499.1 - 0.044 13.6 2.5 0.66 9.7 0.1 2.2 1 1 1 2 2 2 0 DNA-K related protein YbjQ_1 PF01906.17 EKX51500.1 - 0.13 12.9 0.1 0.18 12.5 0.1 1.2 1 0 0 1 1 1 0 Putative heavy-metal-binding TPR_12 PF13424.6 EKX51502.1 - 1.1e-11 44.8 0.3 1.7e-08 34.7 0.0 3.5 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX51502.1 - 1.9e-07 30.8 0.8 2.6e-07 30.3 0.8 1.2 1 0 0 1 1 1 1 MalT-like TPR region TPR_8 PF13181.6 EKX51502.1 - 3.9e-06 26.6 3.2 0.024 14.8 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX51502.1 - 2.1e-05 24.2 2.2 1.1 9.2 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX51502.1 - 7.9e-05 23.2 3.2 5.8 8.0 0.0 4.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX51502.1 - 0.00015 22.2 3.7 0.0067 16.9 0.1 3.2 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX51502.1 - 0.00085 19.9 0.8 9.1 7.0 0.0 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX51502.1 - 0.002 18.0 2.4 0.12 12.5 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX51502.1 - 0.0022 17.7 0.0 0.25 11.2 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX51502.1 - 0.084 13.0 1.4 7.6 6.9 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DHDPS PF00701.22 EKX51503.1 - 1.9e-82 276.2 0.0 2.2e-82 276.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Copine PF07002.16 EKX51504.1 - 1.2e-73 247.1 0.0 1.8e-73 246.6 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 EKX51504.1 - 8.4e-16 58.1 2.1 3.2e-06 27.4 0.1 3.5 3 1 0 3 3 3 2 C2 domain WW PF00397.26 EKX51504.1 - 6.9e-09 35.6 0.1 1.5e-08 34.6 0.1 1.6 1 0 0 1 1 1 1 WW domain vWA-TerF-like PF10138.9 EKX51504.1 - 9.4e-06 25.9 0.0 1.6e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_3 PF13768.6 EKX51504.1 - 0.03 14.3 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain EamA PF00892.20 EKX51504.1 - 0.081 13.1 1.7 0.17 12.1 1.7 1.4 1 0 0 1 1 1 0 EamA-like transporter family Methyltransf_23 PF13489.6 EKX51505.1 - 5.8e-05 23.0 0.0 0.00035 20.4 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain YdjM PF04307.14 EKX51505.1 - 0.0014 18.0 0.0 0.24 10.7 0.0 2.2 2 0 0 2 2 2 2 LexA-binding, inner membrane-associated putative hydrolase DUF735 PF05246.11 EKX51506.1 - 0.052 13.5 0.2 0.071 13.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF735) IF3_C PF00707.22 EKX51507.1 - 1.6e-31 108.1 1.9 2.5e-31 107.5 1.9 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 EKX51507.1 - 5.6e-25 87.4 0.2 1.2e-24 86.4 0.2 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.6 EKX51507.1 - 0.003 17.2 3.3 0.0044 16.7 3.3 1.2 1 0 0 1 1 1 1 Mitochondrial translation initiation factor MULE PF10551.9 EKX51509.1 - 3.5e-06 27.3 0.0 4.7e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 MULE transposase domain DDE_Tnp_ISL3 PF01610.17 EKX51509.1 - 0.011 15.5 0.0 0.012 15.4 0.0 1.1 1 0 0 1 1 1 0 Transposase Transposase_mut PF00872.18 EKX51509.1 - 0.1 11.4 0.0 0.1 11.4 0.0 1.0 1 0 0 1 1 1 0 Transposase, Mutator family DUF2634 PF10934.8 EKX51510.1 - 0.11 12.6 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2634) Methyltransf_16 PF10294.9 EKX51512.1 - 2.9e-22 79.2 0.0 5.1e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 EKX51512.1 - 8.6e-07 29.6 0.0 1.8e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX51512.1 - 7.2e-06 25.9 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EKX51512.1 - 4.3e-05 23.1 0.0 7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EKX51512.1 - 0.00013 21.8 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 EKX51512.1 - 0.0061 16.3 0.0 0.0087 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_12 PF08242.12 EKX51512.1 - 0.0082 16.9 0.0 0.019 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 EKX51512.1 - 0.027 13.8 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_PK PF05891.12 EKX51512.1 - 0.029 13.9 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase DUF4079 PF13301.6 EKX51514.1 - 1e-20 74.3 6.6 1.5e-20 73.7 6.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4079) Cytochrom_B561 PF03188.16 EKX51514.1 - 0.15 12.2 9.4 0.031 14.4 5.1 1.9 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 DUF2231 PF09990.9 EKX51514.1 - 0.59 10.6 5.4 0.54 10.7 1.7 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) Ni_hydr_CYTB PF01292.20 EKX51514.1 - 3.2 7.3 10.8 53 3.3 10.8 2.4 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 PepSY_TM PF03929.16 EKX51514.1 - 6.3 6.4 12.1 0.27 10.9 2.6 2.2 1 1 1 2 2 2 0 PepSY-associated TM region DUF1126 PF06565.12 EKX51515.1 - 1.1e-84 279.1 4.2 1.8e-32 111.3 0.5 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_7 PF13499.6 EKX51515.1 - 4.6e-08 33.4 1.2 1.4e-07 31.9 1.2 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX51515.1 - 0.00022 20.9 0.6 0.0082 16.0 0.1 3.2 1 1 1 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EKX51515.1 - 0.0019 17.6 2.5 0.015 14.8 0.1 2.9 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EKX51515.1 - 0.052 13.4 2.3 0.49 10.3 0.1 2.9 2 1 1 3 3 3 0 EF-hand domain pair Cor1 PF04803.12 EKX51515.1 - 2 8.6 4.5 1.7 8.8 1.7 2.1 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region ABC_tran PF00005.27 EKX51516.1 - 1.3e-46 158.5 0.0 6.3e-24 85.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 EKX51516.1 - 5.8e-46 156.6 52.9 3.3e-24 85.5 22.1 2.4 2 0 0 2 2 2 2 ABC-2 type transporter AAA_16 PF13191.6 EKX51516.1 - 1.2e-08 35.5 0.0 0.00052 20.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 EKX51516.1 - 1.9e-08 34.5 0.0 0.02 14.7 0.0 4.1 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EKX51516.1 - 2.8e-08 33.5 0.0 0.0021 17.6 0.0 2.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EKX51516.1 - 1.3e-06 28.1 0.3 0.01 15.6 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 EKX51516.1 - 1.3e-06 29.0 0.0 0.0064 17.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EKX51516.1 - 4.4e-06 26.4 0.9 0.024 14.2 1.5 3.3 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EKX51516.1 - 7.1e-06 26.0 0.1 0.0014 18.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EKX51516.1 - 4.6e-05 23.7 0.1 0.41 10.9 0.1 2.9 2 2 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EKX51516.1 - 4.7e-05 23.4 1.1 0.041 14.0 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 EKX51516.1 - 0.00021 21.7 0.5 1.4 9.3 0.0 3.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EKX51516.1 - 0.00027 21.2 0.5 3.3 7.9 0.6 3.6 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 EKX51516.1 - 0.00046 20.4 0.2 0.97 9.6 0.2 3.0 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EKX51516.1 - 0.0032 17.2 0.1 1.9 8.1 0.2 2.4 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EKX51516.1 - 0.0072 16.3 0.9 4.1 7.3 0.0 3.4 3 0 0 3 3 3 1 NTPase RNA_helicase PF00910.22 EKX51516.1 - 0.011 16.2 0.1 1.9 8.9 0.0 3.2 3 0 0 3 3 3 0 RNA helicase AAA_24 PF13479.6 EKX51516.1 - 0.019 14.7 0.7 14 5.3 0.8 3.2 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 EKX51516.1 - 0.023 14.9 0.0 0.16 12.3 0.0 2.3 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATPase_2 PF01637.18 EKX51516.1 - 0.023 14.6 0.0 0.65 9.9 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea RuvB_N PF05496.12 EKX51516.1 - 0.024 14.4 0.1 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 EKX51516.1 - 0.027 14.4 0.1 0.9 9.4 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_23 PF13476.6 EKX51516.1 - 0.037 14.5 0.8 0.87 10.0 0.5 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EKX51516.1 - 0.037 14.0 0.0 3.4 7.5 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Roc PF08477.13 EKX51516.1 - 0.043 14.0 0.0 6.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 EKX51516.1 - 0.049 13.2 1.9 0.44 10.1 0.7 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 EKX51516.1 - 0.056 13.9 0.1 3.1 8.2 0.0 3.0 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.12 EKX51516.1 - 0.08 12.2 0.1 7.9 5.7 0.2 2.3 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.23 EKX51516.1 - 0.14 12.2 0.0 4.3 7.4 0.0 2.8 3 0 0 3 3 3 0 Dynamin family AAA_19 PF13245.6 EKX51516.1 - 0.18 12.2 0.3 27 5.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 EKX51516.1 - 0.23 11.0 0.2 27 4.2 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B ABC2_membrane_3 PF12698.7 EKX51516.1 - 6.9 5.7 55.3 1.5 7.9 24.1 3.0 2 1 1 3 3 3 0 ABC-2 family transporter protein Lactamase_B_6 PF16661.5 EKX51517.1 - 2.7e-10 40.0 0.0 1.6e-09 37.5 0.0 2.2 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 EKX51517.1 - 7.1e-08 32.7 0.0 1.9e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 Beta-Casp domain Diphthami_syn_2 PF01902.17 EKX51518.1 - 0.036 13.6 0.1 0.13 11.7 0.1 1.9 1 1 1 2 2 2 0 Diphthamide synthase Mito_carr PF00153.27 EKX51519.1 - 2.3e-53 178.1 4.8 7.1e-22 77.1 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Lipase_3 PF01764.25 EKX51519.1 - 0.16 11.8 0.5 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) ThrE_2 PF12821.7 EKX51519.1 - 0.85 9.8 7.0 0.2 11.8 1.8 2.4 2 0 0 2 2 2 0 Threonine/Serine exporter, ThrE ELO PF01151.18 EKX51520.1 - 1.1e-52 179.1 28.2 1.3e-52 178.8 28.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Fungus-induced PF10917.8 EKX51520.1 - 0.028 14.7 1.8 0.028 14.7 1.8 2.3 2 0 0 2 2 2 0 Fungus-induced protein EF-hand_7 PF13499.6 EKX51521.1 - 1e-13 51.5 0.0 0.0024 18.3 0.0 4.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EKX51521.1 - 1.1e-12 46.5 0.5 0.17 11.5 0.0 5.8 5 0 0 5 5 5 3 EF hand Ion_trans_2 PF07885.16 EKX51521.1 - 1.5e-11 44.0 11.5 1.5e-11 44.0 11.5 2.1 2 1 0 2 2 2 1 Ion channel EF-hand_5 PF13202.6 EKX51521.1 - 3.5e-10 38.9 3.3 0.018 14.5 0.0 5.4 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 EKX51521.1 - 5.6e-09 35.2 4.4 0.32 11.1 0.0 5.4 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 EKX51521.1 - 3.8e-08 33.0 1.4 0.43 10.5 0.0 4.9 4 1 1 5 5 5 2 EF-hand domain pair Ion_trans PF00520.31 EKX51521.1 - 1.5e-06 27.6 10.5 1.5e-06 27.6 10.5 1.7 2 0 0 2 2 2 1 Ion transport protein SBP_bac_3 PF00497.20 EKX51521.1 - 1.2e-05 24.9 0.0 0.045 13.2 0.0 2.6 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.26 EKX51521.1 - 0.00067 19.5 0.1 0.0018 18.2 0.1 1.7 1 1 0 1 1 1 1 Ligand-gated ion channel SPARC_Ca_bdg PF10591.9 EKX51521.1 - 0.037 14.4 0.3 3.4 8.0 0.0 3.4 2 2 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region AmpE PF17113.5 EKX51521.1 - 0.14 11.5 0.3 0.24 10.7 0.3 1.3 1 0 0 1 1 1 0 Regulatory signalling modulator protein AmpE IRK PF01007.20 EKX51521.1 - 1.1 9.1 9.2 9.1 6.1 0.1 2.6 1 1 1 2 2 2 0 Inward rectifier potassium channel transmembrane domain SWIRM-assoc_2 PF16496.5 EKX51523.1 - 1.5e-53 182.2 0.9 2.6e-53 181.4 0.9 1.3 1 0 0 1 1 1 1 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 EKX51523.1 - 7.2e-29 100.0 0.1 3.2e-28 97.9 0.0 2.2 2 0 0 2 2 2 1 SWIRM domain SWIRM-assoc_1 PF16495.5 EKX51523.1 - 7.2e-14 51.5 8.0 7.2e-14 51.5 8.0 2.3 2 0 0 2 2 2 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 EKX51523.1 - 2e-12 47.1 0.2 5.7e-12 45.6 0.2 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX51523.1 - 3.6e-07 30.3 0.6 3.6e-07 30.3 0.6 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EKX51523.1 - 0.014 15.2 0.2 0.014 15.2 0.2 2.3 2 0 0 2 2 2 0 Myb DNA-binding like Spectrin PF00435.21 EKX51523.1 - 0.59 10.7 6.1 0.21 12.1 0.4 2.7 2 0 0 2 2 2 0 Spectrin repeat Radial_spoke_3 PF06098.11 EKX51524.1 - 4.7e-101 337.8 24.3 3.1e-63 213.7 7.8 2.7 2 1 1 3 3 3 2 Radial spoke protein 3 Laminin_G_3 PF13385.6 EKX51525.1 - 1.8e-08 34.6 3.0 0.00011 22.3 0.0 4.6 4 0 0 4 4 4 2 Concanavalin A-like lectin/glucanases superfamily LysM PF01476.20 EKX51525.1 - 1.6e-06 28.1 0.0 0.0013 18.7 0.0 3.1 3 0 0 3 3 3 2 LysM domain Sel1 PF08238.12 EKX51526.1 - 8.5e-16 58.1 7.1 0.013 16.2 0.5 5.7 5 0 0 5 5 5 4 Sel1 repeat TPR_8 PF13181.6 EKX51526.1 - 4e-07 29.7 4.0 0.0038 17.3 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat CS PF04969.16 EKX51526.1 - 1.4e-06 29.2 0.2 3.5e-06 28.0 0.2 1.6 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 EKX51526.1 - 4.2e-05 23.3 7.4 0.41 10.9 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX51526.1 - 0.00023 20.8 6.6 0.036 13.9 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX51526.1 - 0.00085 19.6 1.7 0.037 14.3 0.0 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX51526.1 - 0.0013 18.6 2.3 0.98 9.6 0.0 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat DUF3856 PF12968.7 EKX51526.1 - 0.084 12.9 0.2 0.26 11.3 0.0 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_17 PF13431.6 EKX51526.1 - 0.089 13.2 0.3 18 6.0 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX51526.1 - 0.23 12.4 4.9 4.2 8.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Glycos_transf_1 PF00534.20 EKX51527.1 - 2.9e-13 49.7 0.0 9.3e-13 48.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EKX51527.1 - 2.9e-10 40.7 0.1 6.7e-10 39.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EKX51527.1 - 0.036 14.4 0.0 0.093 13.1 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferases group 1 3Beta_HSD PF01073.19 EKX51527.1 - 0.087 11.8 0.2 0.57 9.1 0.1 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Carbam_trans_N PF02543.15 EKX51527.1 - 0.094 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus HAUS2 PF15003.6 EKX51530.1 - 0.0061 16.3 1.7 0.017 14.8 1.7 1.7 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 2 DUF641 PF04859.12 EKX51530.1 - 0.011 16.1 4.2 0.011 16.1 4.2 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Imm3 PF14425.6 EKX51530.1 - 0.025 14.6 3.0 1.4 9.0 0.3 2.5 2 0 0 2 2 2 0 Immunity protein Imm3 PRP1_N PF06424.12 EKX51530.1 - 0.026 14.9 6.1 0.35 11.3 2.2 2.3 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DUF2203 PF09969.9 EKX51530.1 - 0.056 14.2 6.3 0.52 11.0 0.2 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) CAMSAP_CC1 PF17095.5 EKX51530.1 - 0.2 11.5 6.8 0.13 12.2 4.4 1.9 2 0 0 2 2 2 0 Spectrin-binding region of Ca2+-Calmodulin DUF5094 PF17015.5 EKX51530.1 - 0.21 11.7 7.2 0.038 14.1 3.7 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF5094) FlxA PF14282.6 EKX51530.1 - 0.22 11.5 0.2 0.22 11.5 0.2 2.5 2 1 0 2 2 2 0 FlxA-like protein TMF_TATA_bd PF12325.8 EKX51530.1 - 0.24 11.6 11.0 1.1 9.5 0.6 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3450 PF11932.8 EKX51530.1 - 0.25 10.6 7.8 0.69 9.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Snapin_Pallidin PF14712.6 EKX51530.1 - 0.41 11.1 8.4 0.55 10.7 2.4 3.1 3 0 0 3 3 3 0 Snapin/Pallidin NPV_P10 PF05531.12 EKX51530.1 - 1.3 9.6 5.0 11 6.6 0.6 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF724 PF05266.14 EKX51530.1 - 1.3 8.8 8.1 0.58 10.0 4.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Csm1_N PF18504.1 EKX51530.1 - 2 8.8 13.2 0.65 10.4 4.8 3.0 2 1 1 3 3 3 0 Csm1 N-terminal domain DUF16 PF01519.16 EKX51530.1 - 2.4 8.7 6.6 3.5 8.2 2.0 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF16 TSC22 PF01166.18 EKX51530.1 - 2.8 8.3 7.8 0.9 9.9 2.8 2.6 3 0 0 3 3 3 0 TSC-22/dip/bun family FlaC_arch PF05377.11 EKX51530.1 - 4.5 7.7 7.6 31 5.0 0.0 2.8 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) DUF1451 PF07295.11 EKX51530.1 - 5.4 7.0 8.2 1.3 9.0 4.0 2.0 2 0 0 2 2 2 0 Zinc-ribbon containing domain IFT20 PF14931.6 EKX51530.1 - 5.4 7.2 10.7 1.1 9.5 4.1 2.4 2 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 TMF_DNA_bd PF12329.8 EKX51530.1 - 6.7 6.8 14.2 0.6 10.2 7.0 2.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 EKX51530.1 - 7.8 7.2 11.5 29 5.4 0.1 2.9 3 1 0 3 3 2 0 SlyX PDZ_6 PF17820.1 EKX51531.1 - 6.1e-08 32.4 0.0 2e-07 30.7 0.0 2.0 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX51531.1 - 0.0005 20.4 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX51531.1 - 0.0064 16.8 0.1 0.018 15.3 0.1 1.8 1 0 0 1 1 1 1 PDZ domain Fez1 PF06818.15 EKX51531.1 - 0.0086 16.6 20.2 0.0086 16.6 20.2 3.3 2 1 1 3 3 3 1 Fez1 Spc7 PF08317.11 EKX51531.1 - 2.1 7.1 54.3 0.39 9.5 17.6 4.0 1 1 3 4 4 4 0 Spc7 kinetochore protein HDV_ag PF01517.18 EKX51531.1 - 2.5 7.8 11.9 0.47 10.2 4.6 3.1 3 0 0 3 3 3 0 Hepatitis delta virus delta antigen HalX PF08663.10 EKX51531.1 - 7.8 6.9 11.9 0.2 12.0 1.7 3.3 2 0 0 2 2 2 0 HalX domain DUF2353 PF09789.9 EKX51532.1 - 1.5e-05 24.5 29.1 1.5e-05 24.5 29.1 2.1 1 1 1 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) ADIP PF11559.8 EKX51532.1 - 0.013 15.6 17.6 0.013 15.6 17.6 3.4 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 EKX51532.1 - 0.029 15.0 3.9 0.029 15.0 3.9 3.6 3 1 0 3 3 3 0 Initiation control protein YabA HMMR_C PF15908.5 EKX51532.1 - 0.08 13.2 0.3 0.08 13.2 0.3 3.2 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor C-terminal ATG16 PF08614.11 EKX51532.1 - 0.1 12.8 37.4 0.057 13.6 27.9 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 EKX51532.1 - 0.57 10.0 39.5 11 5.8 26.1 2.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Rootletin PF15035.6 EKX51532.1 - 0.64 10.0 35.4 0.25 11.3 26.8 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Uso1_p115_C PF04871.13 EKX51532.1 - 1.1 9.7 43.2 2.1 8.7 22.4 3.9 1 1 2 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fez1 PF06818.15 EKX51532.1 - 1.4 9.3 37.5 10 6.5 32.7 2.8 1 1 1 2 2 2 0 Fez1 FlaC_arch PF05377.11 EKX51532.1 - 1.5 9.2 19.5 4.8 7.7 1.8 4.4 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) DDE_Tnp_ISL3 PF01610.17 EKX51532.1 - 2.1 8.0 14.4 1.4 8.6 10.8 2.4 1 1 1 3 3 3 0 Transposase ZapB PF06005.12 EKX51532.1 - 3.1 8.3 43.7 16 6.0 8.5 4.4 2 2 1 3 3 3 0 Cell division protein ZapB CALCOCO1 PF07888.11 EKX51532.1 - 4.1 6.1 41.2 20 3.9 41.2 2.0 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like EzrA PF06160.12 EKX51532.1 - 4.8 5.2 30.3 1.5 6.9 0.7 2.7 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA PRKG1_interact PF15898.5 EKX51532.1 - 5.4 8.0 42.2 0.54 11.2 13.7 3.3 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain Lebercilin PF15619.6 EKX51532.1 - 5.8 6.5 46.3 0.67 9.6 3.1 3.2 1 1 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease FAM184 PF15665.5 EKX51532.1 - 8.4 6.1 37.5 0.87 9.3 18.7 3.1 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B Cnn_1N PF07989.11 EKX51532.1 - 9.3 6.5 35.9 5.4 7.3 3.6 4.5 2 1 2 4 4 4 0 Centrosomin N-terminal motif 1 Zeta_toxin PF06414.12 EKX51533.1 - 1.9e-20 73.0 0.0 3e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 EKX51533.1 - 3e-06 27.5 0.0 1.3e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EKX51533.1 - 7.8e-06 26.5 0.0 1.8e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain eIF3_subunit PF08597.10 EKX51534.1 - 4.7e-13 49.6 30.0 4.7e-13 49.6 30.0 2.8 1 1 2 3 3 3 2 Translation initiation factor eIF3 subunit DUF3050 PF11251.8 EKX51534.1 - 0.067 12.8 1.9 0.081 12.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3050) DUF806 PF05657.11 EKX51534.1 - 0.13 12.7 1.9 0.45 11.0 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF806) TIR_2 PF13676.6 EKX51538.1 - 1.3e-10 41.9 0.1 2.1e-10 41.2 0.1 1.3 1 1 0 1 1 1 1 TIR domain TIR PF01582.20 EKX51538.1 - 0.023 14.5 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 TIR domain DinB_2 PF12867.7 EKX51538.1 - 0.077 13.5 0.1 0.19 12.2 0.1 1.7 1 1 0 1 1 1 0 DinB superfamily He_PIG PF05345.12 EKX51539.1 - 1.3e-28 99.0 0.7 0.003 17.7 0.0 9.1 9 0 0 9 9 9 7 Putative Ig domain Ank_5 PF13857.6 EKX51539.1 - 0.0016 18.7 0.4 0.0039 17.5 0.4 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX51539.1 - 0.0072 16.9 0.0 0.022 15.4 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Poty_PP PF08440.10 EKX51539.1 - 0.21 10.6 3.0 0.72 8.9 0.3 2.5 2 0 0 2 2 2 0 Potyviridae polyprotein I-set PF07679.16 EKX51539.1 - 0.62 10.2 2.8 14 5.9 0.1 3.9 4 0 0 4 4 4 0 Immunoglobulin I-set domain CCDC23 PF15674.5 EKX51540.1 - 0.006 16.6 10.8 0.0073 16.3 9.3 1.9 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 23 FAM199X PF15814.5 EKX51540.1 - 0.024 13.7 5.3 0.037 13.1 5.3 1.4 1 0 0 1 1 1 0 Protein family FAM199X PPR_2 PF13041.6 EKX51541.1 - 2.1e-12 47.0 0.6 1.2e-06 28.6 0.1 3.5 3 1 0 3 3 3 2 PPR repeat family PPR_3 PF13812.6 EKX51541.1 - 1.9e-10 40.7 0.0 2.3e-07 30.8 0.0 3.1 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_long PF17177.4 EKX51541.1 - 3.8e-08 32.9 0.1 7.5e-08 32.0 0.1 1.4 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EKX51541.1 - 0.038 14.2 9.4 7.5 7.0 0.0 5.9 6 0 0 6 6 6 0 PPR repeat PPR_1 PF12854.7 EKX51541.1 - 0.17 11.6 0.4 18 5.1 0.0 3.8 3 0 0 3 3 3 0 PPR repeat DASH_Ask1 PF08655.10 EKX51542.1 - 4.9e-07 29.5 0.2 1.3e-06 28.2 0.2 1.7 2 0 0 2 2 2 1 DASH complex subunit Ask1 DUF1542 PF07564.11 EKX51542.1 - 0.053 13.6 1.5 0.089 12.9 1.5 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) GCN5L1 PF06320.13 EKX51542.1 - 0.07 13.3 1.1 0.12 12.5 1.1 1.3 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) Lectin_N PF03954.14 EKX51542.1 - 0.13 12.0 0.2 0.21 11.3 0.2 1.3 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DLH PF01738.18 EKX51543.1 - 6.2e-39 133.8 0.1 7.4e-39 133.5 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 EKX51543.1 - 8.4e-06 25.8 0.9 0.0094 15.8 0.3 2.8 1 1 1 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.11 EKX51543.1 - 3.3e-05 23.9 0.3 0.00039 20.4 0.1 2.1 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 EKX51543.1 - 0.0017 17.9 0.3 0.77 9.2 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EKX51543.1 - 0.0087 16.7 0.3 0.017 15.7 0.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 EKX51543.1 - 0.055 13.1 0.1 0.09 12.4 0.1 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 EKX51543.1 - 0.1 11.9 0.2 2.1 7.5 0.1 2.2 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EKX51543.1 - 0.13 12.0 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 EKX51543.1 - 0.17 11.5 0.1 0.48 10.0 0.1 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold Esterase PF00756.20 EKX51543.1 - 0.23 11.1 1.3 0.52 9.9 0.5 2.1 2 1 0 2 2 2 0 Putative esterase DUF4062 PF13271.6 EKX51544.1 - 4.1e-08 33.5 0.0 2.6e-07 30.9 0.0 2.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) AAA_16 PF13191.6 EKX51544.1 - 0.0068 16.8 0.1 0.14 12.5 0.0 3.2 2 0 0 2 2 2 1 AAA ATPase domain DUF4093 PF13331.6 EKX51544.1 - 0.073 13.5 0.9 0.38 11.2 0.9 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4093) DUF3890 PF13029.6 EKX51544.1 - 1.1 9.7 5.4 29 5.2 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3890) 2C_adapt PF08793.10 EKX51545.1 - 0.32 11.2 2.6 0.48 10.7 0.3 2.0 2 0 0 2 2 2 0 2-cysteine adaptor domain LysM PF01476.20 EKX51546.1 - 3.1e-15 55.9 0.2 3.6e-10 39.7 0.0 2.8 2 0 0 2 2 2 2 LysM domain DUF4159 PF13709.6 EKX51548.1 - 0.072 12.5 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) Nuc_sug_transp PF04142.15 EKX51550.1 - 2.2e-30 105.9 2.9 2.6e-30 105.7 2.9 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 EKX51550.1 - 3.2e-07 29.9 0.4 3.2e-07 29.9 0.4 1.7 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport EamA PF00892.20 EKX51550.1 - 0.0013 18.9 15.3 0.008 16.3 9.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family TRAM1 PF08390.11 EKX51550.1 - 1.1 9.0 7.3 4.5 7.0 0.4 2.4 2 0 0 2 2 2 0 TRAM1-like protein TBP PF00352.21 EKX51552.1 - 7.1e-12 45.1 0.2 0.0001 22.2 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) HOIP-UBA PF16678.5 EKX51553.1 - 0.15 12.1 3.1 0.58 10.2 2.0 1.9 1 1 1 2 2 2 0 HOIP UBA domain pair DUF4355 PF14265.6 EKX51553.1 - 0.42 10.9 6.9 0.49 10.6 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) cNMP_binding PF00027.29 EKX51554.1 - 1.5e-12 47.4 0.0 3.1e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF4846 PF16138.5 EKX51554.1 - 0.12 11.9 0.8 0.41 10.1 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (4846) PPR_2 PF13041.6 EKX51555.1 - 4.6e-16 58.7 2.5 0.00043 20.4 0.2 7.8 5 2 4 9 9 9 4 PPR repeat family PPR PF01535.20 EKX51555.1 - 7.8e-12 44.6 10.3 0.03 14.6 0.8 7.9 8 0 0 8 8 8 3 PPR repeat PPR_3 PF13812.6 EKX51555.1 - 6.7e-08 32.5 1.1 0.047 13.8 0.0 5.4 4 2 2 6 6 6 3 Pentatricopeptide repeat domain PPR_long PF17177.4 EKX51555.1 - 8.9e-05 21.9 0.7 1 8.7 0.0 3.6 2 1 2 4 4 4 2 Pentacotripeptide-repeat region of PRORP Clathrin PF00637.20 EKX51555.1 - 0.0006 19.7 4.4 0.31 10.9 0.1 3.4 2 1 1 3 3 3 2 Region in Clathrin and VPS PPR_1 PF12854.7 EKX51555.1 - 0.0011 18.7 16.8 0.042 13.5 0.0 6.6 7 0 0 7 7 7 2 PPR repeat Dynactin PF12455.8 EKX51555.1 - 0.0019 17.5 2.5 0.0056 16.0 0.1 2.4 2 1 0 2 2 2 1 Dynein associated protein DUF5598 PF18127.1 EKX51555.1 - 0.0044 17.4 0.1 5.8 7.4 0.1 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF5598) IL6 PF00489.17 EKX51555.1 - 0.02 14.5 0.6 0.02 14.5 0.6 1.8 2 0 0 2 2 2 0 Interleukin-6/G-CSF/MGF family UQ_con PF00179.26 EKX51556.1 - 2.9e-37 127.4 0.0 3.5e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EKX51556.1 - 0.12 12.7 0.2 0.29 11.4 0.1 1.6 1 1 0 2 2 2 0 RWD domain ERM PF00769.19 EKX51557.1 - 0.009 15.9 25.8 0.009 15.9 25.8 2.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family AAA_15 PF13175.6 EKX51557.1 - 0.34 10.6 28.1 0.5 10.0 28.1 1.3 1 0 0 1 1 1 0 AAA ATPase domain MAT1 PF06391.13 EKX51559.1 - 0.0013 18.6 6.0 0.0019 18.1 6.0 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 HR1 PF02185.16 EKX51559.1 - 0.23 11.6 3.4 0.54 10.4 0.1 2.6 1 1 1 2 2 2 0 Hr1 repeat E1-E2_ATPase PF00122.20 EKX51560.1 - 4e-52 176.3 2.4 4e-52 176.3 2.4 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EKX51560.1 - 8.1e-39 134.1 0.5 1.9e-38 132.9 0.5 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EKX51560.1 - 4.5e-30 103.9 11.8 2.8e-13 50.1 0.3 4.2 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EKX51560.1 - 4.3e-05 23.4 2.2 0.00017 21.4 0.7 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EKX51560.1 - 0.002 18.6 0.0 0.0047 17.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3349 PF11829.8 EKX51560.1 - 0.56 11.0 3.9 2.2 9.1 0.0 3.5 5 0 0 5 5 5 0 Protein of unknown function (DUF3349) Fer2_BFD PF04324.15 EKX51560.1 - 7.8 6.9 13.9 20 5.6 0.1 4.4 4 0 0 4 4 4 0 BFD-like [2Fe-2S] binding domain HEAT_2 PF13646.6 EKX51561.1 - 3.9e-07 30.4 0.0 0.012 16.0 0.0 4.2 1 1 3 4 4 4 2 HEAT repeats HEAT PF02985.22 EKX51561.1 - 6e-06 26.1 3.2 1.1 9.7 0.0 5.6 6 0 0 6 6 6 1 HEAT repeat Pro_3_hydrox_C PF05373.11 EKX51561.1 - 0.02 15.0 0.3 0.32 11.1 0.0 3.0 2 0 0 2 2 2 0 L-proline 3-hydroxylase, C-terminal Cnd1 PF12717.7 EKX51561.1 - 0.046 13.8 18.9 0.15 12.1 1.0 4.0 2 1 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EKX51561.1 - 0.059 13.9 0.0 49 4.6 0.0 4.0 4 0 0 4 4 4 0 HEAT-like repeat ATP-cone PF03477.16 EKX51561.1 - 0.12 12.9 0.5 0.52 10.9 0.5 2.2 1 0 0 1 1 1 0 ATP cone domain DUF4806 PF16064.5 EKX51561.1 - 0.59 10.5 6.0 10 6.5 0.2 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4806) Cytochrom_C PF00034.21 EKX51562.1 - 4.8e-14 53.3 0.0 6.7e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EKX51562.1 - 2.2e-06 27.9 3.2 6.7e-06 26.3 3.2 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EKX51562.1 - 0.00065 19.4 0.3 0.0014 18.4 0.1 1.7 2 1 1 3 3 3 1 Cytochrome c-550 domain DHOR PF06537.11 EKX51562.1 - 0.058 12.0 0.0 0.56 8.8 0.0 2.0 2 0 0 2 2 2 0 Di-haem oxidoreductase, putative peroxidase Cytochrome_P460 PF16694.5 EKX51562.1 - 0.13 12.6 0.5 2.7 8.4 0.2 2.0 2 0 0 2 2 2 0 Cytochrome P460 EF-hand_7 PF13499.6 EKX51563.1 - 0.00083 19.8 0.0 0.86 10.1 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX51563.1 - 0.001 18.8 0.2 0.21 11.6 0.0 3.2 4 0 0 4 4 4 1 EF-hand domain EF-hand_9 PF14658.6 EKX51563.1 - 0.0038 17.5 0.0 0.11 12.8 0.0 2.4 2 1 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 EKX51563.1 - 0.031 14.1 0.1 1.4 8.9 0.0 3.2 3 1 0 3 3 3 0 EF-hand domain pair DUF1825 PF08855.10 EKX51563.1 - 0.037 13.9 0.1 0.086 12.8 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1825) PDZ_2 PF13180.6 EKX51564.1 - 3e-05 24.3 0.5 9.7e-05 22.6 0.5 1.8 1 1 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX51564.1 - 0.00056 19.7 0.4 0.0015 18.3 0.4 1.8 1 0 0 1 1 1 1 PDZ domain ZapB PF06005.12 EKX51564.1 - 0.0019 18.6 22.1 0.028 14.8 6.5 4.3 4 0 0 4 4 4 2 Cell division protein ZapB ATP-synt_S1 PF05827.12 EKX51564.1 - 0.0073 16.1 0.1 0.025 14.4 0.1 1.9 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) PDZ PF00595.24 EKX51564.1 - 0.015 15.6 0.6 0.04 14.3 0.6 1.7 1 0 0 1 1 1 0 PDZ domain DUF745 PF05335.13 EKX51564.1 - 0.022 14.5 12.3 0.053 13.2 8.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF745) ERM PF00769.19 EKX51564.1 - 0.077 12.8 17.5 0.42 10.4 17.3 2.2 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Tricorn_PDZ PF14685.6 EKX51564.1 - 0.14 12.1 0.8 0.54 10.3 0.6 2.0 2 0 0 2 2 2 0 Tricorn protease PDZ domain Lipoprotein_3 PF00938.17 EKX51564.1 - 0.39 10.9 3.0 1.4 9.2 0.0 3.1 3 1 1 4 4 4 0 Lipoprotein Mit_KHE1 PF10173.9 EKX51564.1 - 1.1 9.3 6.5 3.1 7.9 6.5 1.7 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Helitron_like_N PF14214.6 EKX51564.1 - 2.4 8.3 6.3 11 6.2 6.2 2.2 1 1 0 1 1 1 0 Helitron helicase-like domain at N-terminus TPR_MLP1_2 PF07926.12 EKX51564.1 - 4.5 7.3 20.8 0.23 11.5 5.1 3.2 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.22 EKX51564.1 - 8.9 6.6 22.7 0.92 9.8 4.5 3.1 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain WD40 PF00400.32 EKX51565.1 - 4.6e-23 81.1 5.4 7.2e-07 29.8 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX51565.1 - 3e-06 27.5 0.3 0.0079 16.5 0.1 3.6 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EKX51565.1 - 0.0094 15.6 0.7 0.013 15.1 0.7 1.5 1 1 0 1 1 1 1 PQQ-like domain WD40_like PF17005.5 EKX51565.1 - 0.044 13.1 0.2 5.4 6.3 0.1 2.3 1 1 0 2 2 2 0 WD40-like domain BBS2_Mid PF14783.6 EKX51565.1 - 0.059 13.4 0.2 36 4.4 0.0 2.7 1 1 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.11 EKX51565.1 - 0.077 11.7 0.5 0.47 9.1 0.1 2.1 1 1 0 1 1 1 0 Nup133 N terminal like CVNH PF08881.10 EKX51565.1 - 0.082 13.6 0.1 0.14 12.9 0.1 1.5 1 0 0 1 1 1 0 CVNH domain EF-hand_1 PF00036.32 EKX51566.1 - 3.2e-14 51.3 6.7 1.1e-06 27.8 2.6 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX51566.1 - 1.3e-12 46.6 3.5 5.1e-06 26.0 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EKX51566.1 - 3.6e-12 46.5 1.5 3.9e-12 46.5 1.5 1.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX51566.1 - 1.6e-10 40.0 6.6 4.1e-05 22.9 0.3 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX51566.1 - 2e-10 40.4 5.0 1.9e-05 24.4 1.5 2.0 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX51566.1 - 0.016 15.6 0.1 0.02 15.2 0.1 1.1 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EKX51566.1 - 0.03 14.3 3.1 0.72 9.8 0.6 2.0 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Lon_2 PF13337.6 EKX51566.1 - 0.052 12.1 0.1 0.054 12.0 0.1 1.0 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease SusD-like_2 PF12771.7 EKX51570.1 - 0.0015 17.5 0.9 0.0022 17.0 0.9 1.1 1 0 0 1 1 1 1 Starch-binding associating with outer membrane PCIF1_WW PF12237.8 EKX51571.1 - 3.5e-53 179.8 1.1 4.8e-53 179.3 1.1 1.2 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain YPEB PF14620.6 EKX51571.1 - 0.034 13.5 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 YpeB sporulation NUFIP1 PF10453.9 EKX51572.1 - 1e-12 47.7 5.5 1e-12 47.7 5.5 2.1 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Torus PF16131.5 EKX51572.1 - 5.2e-07 30.3 1.6 5.2e-07 30.3 1.6 2.0 1 1 1 2 2 2 1 Torus domain zf-CCCH PF00642.24 EKX51572.1 - 1.1e-05 25.2 4.5 2.7e-05 24.0 4.5 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EKX51572.1 - 6.7e-05 22.8 8.7 6.7e-05 22.8 8.7 2.0 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 EKX51572.1 - 0.0053 16.5 5.0 0.011 15.5 5.0 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-C3H1 PF10650.9 EKX51572.1 - 0.017 14.8 0.6 0.036 13.8 0.6 1.6 1 0 0 1 1 1 0 Putative zinc-finger domain zf-CCCH_2 PF14608.6 EKX51572.1 - 0.05 14.1 4.8 0.05 14.1 4.8 2.3 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger BLOC1S3 PF15753.5 EKX51572.1 - 0.1 12.7 0.8 0.17 12.0 0.8 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 zf-C2H2 PF00096.26 EKX51572.1 - 1.8 9.2 4.6 0.37 11.3 0.7 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type bZIP_1 PF00170.21 EKX51576.1 - 5.8e-05 23.1 1.7 0.00013 22.0 1.7 1.6 1 0 0 1 1 1 1 bZIP transcription factor YabA PF06156.13 EKX51576.1 - 0.0028 18.2 0.8 0.006 17.2 0.3 1.9 2 0 0 2 2 1 1 Initiation control protein YabA ZapB PF06005.12 EKX51576.1 - 0.01 16.3 6.1 0.01 16.3 6.1 1.8 2 0 0 2 2 2 0 Cell division protein ZapB DUF3450 PF11932.8 EKX51576.1 - 0.012 14.9 0.2 0.024 13.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.8 EKX51576.1 - 0.013 15.4 2.6 0.025 14.5 2.6 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding RasGAP_C PF03836.15 EKX51576.1 - 0.015 15.4 0.4 0.022 14.9 0.4 1.3 1 0 0 1 1 1 0 RasGAP C-terminus Cas_Cmr5 PF09701.10 EKX51576.1 - 0.017 15.4 0.1 0.11 12.8 0.1 2.4 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Cmr5) Macoilin PF09726.9 EKX51576.1 - 0.041 12.4 0.0 0.043 12.4 0.0 1.1 1 0 0 1 1 1 0 Macoilin family PRKG1_interact PF15898.5 EKX51576.1 - 0.043 14.7 2.5 0.087 13.7 2.5 1.4 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain UPF0242 PF06785.11 EKX51576.1 - 0.044 13.9 0.6 0.094 12.8 0.6 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GIT_CC PF16559.5 EKX51576.1 - 0.057 13.3 0.5 0.13 12.2 0.5 1.6 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.15 EKX51576.1 - 0.06 13.1 2.6 0.077 12.8 1.3 1.9 2 0 0 2 2 2 0 Septum formation initiator CENP-H PF05837.12 EKX51576.1 - 0.06 13.8 0.5 0.11 13.0 0.5 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) HAUS6_N PF14661.6 EKX51576.1 - 0.094 12.3 0.7 0.15 11.6 0.7 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF2205 PF10224.9 EKX51576.1 - 0.11 12.5 1.0 0.22 11.6 1.0 1.5 1 0 0 1 1 1 0 Short coiled-coil protein Tho2 PF11262.8 EKX51576.1 - 0.85 8.8 2.6 1.3 8.2 2.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Pkinase PF00069.25 EKX51577.1 - 5.8e-64 216.0 0.0 6.7e-64 215.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX51577.1 - 2.5e-30 105.7 0.0 3.1e-30 105.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX51577.1 - 5.1e-05 22.7 0.0 8.4e-05 22.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EKX51577.1 - 7.1e-05 21.8 0.0 7.6e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EKX51577.1 - 0.044 13.4 0.0 0.41 10.2 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Asn_synthase PF00733.21 EKX51578.1 - 1.1e-18 68.1 0.2 9.5e-07 28.8 0.0 3.2 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 EKX51578.1 - 1e-09 38.4 0.0 2.1e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EKX51578.1 - 2.2e-05 24.7 0.0 7.2e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain QueC PF06508.13 EKX51578.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 EKX51578.1 - 0.22 11.3 0.0 0.44 10.3 0.0 1.5 1 0 0 1 1 1 0 PP-loop family fn3 PF00041.21 EKX51579.1 - 7.8e-11 42.2 0.0 0.0034 17.7 0.0 5.6 5 1 0 5 5 5 3 Fibronectin type III domain RNA_pol_3_Rpc31 PF11705.8 EKX51579.1 - 0.023 15.0 21.9 0.021 15.1 6.0 3.1 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 Thioredoxin_8 PF13905.6 EKX51579.1 - 0.098 13.0 0.0 6.9 7.1 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin-like BTK PF00779.19 EKX51579.1 - 0.13 12.1 10.3 0.32 10.8 0.8 3.1 3 0 0 3 3 3 0 BTK motif Esterase PF00756.20 EKX51580.1 - 1.8e-05 24.6 0.2 3.3e-05 23.6 0.2 1.4 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 EKX51580.1 - 0.0088 15.6 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 EKX51580.1 - 0.093 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase RINGv PF12906.7 EKX51580.1 - 2 8.6 4.9 2.7 8.2 0.7 2.8 3 0 0 3 3 3 0 RING-variant domain UCH PF00443.29 EKX51581.1 - 0.021 14.3 2.3 0.19 11.2 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase ATP-synt_B PF00430.18 EKX51581.1 - 0.39 10.8 26.0 0.065 13.3 20.7 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) zf-DBF PF07535.12 EKX51581.1 - 1.1 9.5 0.0 1.1 9.5 0.0 3.0 3 0 0 3 3 3 0 DBF zinc finger DUF883 PF05957.13 EKX51581.1 - 9.4 6.9 16.6 3.1 8.5 10.8 2.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF883) Pkinase PF00069.25 EKX51582.1 - 5.7e-34 117.7 0.0 7.9e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX51582.1 - 9.8e-23 80.8 0.0 1.2e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX51582.1 - 0.009 16.0 0.2 0.015 15.3 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX51582.1 - 0.09 11.5 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 EKX51582.1 - 0.24 10.3 0.1 0.6 9.0 0.1 1.6 1 1 0 1 1 1 0 Poxvirus serine/threonine protein kinase BNIP3 PF06553.12 EKX51583.1 - 0.42 10.3 4.9 0.51 10.0 4.9 1.3 1 1 0 1 1 1 0 BNIP3 Transferase PF02458.15 EKX51584.1 - 0.0039 15.9 0.4 0.0041 15.8 0.4 1.0 1 0 0 1 1 1 1 Transferase family Transferase PF02458.15 EKX51585.1 - 0.0034 16.1 0.6 0.0035 16.0 0.6 1.0 1 0 0 1 1 1 1 Transferase family DUF3119 PF11317.8 EKX51586.1 - 4.5e-29 101.3 0.1 4.9e-29 101.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3119) zf-C3HC4 PF00097.25 EKX51587.1 - 0.00056 19.7 0.5 0.00056 19.7 0.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EKX51587.1 - 0.014 15.2 0.3 0.014 15.2 0.3 2.6 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX51587.1 - 0.018 15.1 0.2 0.018 15.1 0.2 2.0 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EKX51587.1 - 0.037 13.9 0.9 0.037 13.9 0.9 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX51587.1 - 0.077 13.0 0.4 0.077 13.0 0.4 2.6 2 1 0 2 2 2 0 zinc-RING finger domain zf-RING_10 PF16685.5 EKX51587.1 - 0.11 12.7 0.3 0.11 12.7 0.3 2.2 2 1 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_2 PF13639.6 EKX51587.1 - 0.13 12.6 0.3 0.13 12.6 0.3 2.6 2 1 0 2 2 2 0 Ring finger domain NTP_transf_4 PF13562.6 EKX51587.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Sugar nucleotidyl transferase OrfB_Zn_ribbon PF07282.11 EKX51587.1 - 3.2 7.7 7.4 3 7.8 2.1 2.5 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-C3HC4_4 PF15227.6 EKX51587.1 - 5.7 7.2 10.2 0.23 11.6 0.4 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING EF-hand_1 PF00036.32 EKX51589.1 - 2.8e-12 45.3 0.1 2.2e-06 26.8 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 EKX51589.1 - 8.2e-12 44.1 0.1 2e-06 27.0 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX51589.1 - 2.3e-10 39.6 0.7 3e-05 23.6 0.0 3.9 3 1 1 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 EKX51589.1 - 6e-08 33.0 0.2 6e-08 33.0 0.2 3.0 4 0 0 4 4 4 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX51589.1 - 0.00061 20.1 1.4 0.017 15.4 0.1 2.8 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF4264 PF14084.6 EKX51589.1 - 0.02 14.5 0.1 0.12 12.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4264) EF-hand_8 PF13833.6 EKX51589.1 - 0.024 14.5 4.7 2.3 8.1 0.0 3.7 4 0 0 4 4 4 0 EF-hand domain pair TUG-UBL1 PF11470.8 EKX51590.1 - 3.9e-16 59.0 0.1 1.6e-15 57.1 0.1 2.0 2 0 0 2 2 2 1 TUG ubiquitin-like domain UBX PF00789.20 EKX51590.1 - 6.6e-11 42.3 0.1 7.1e-09 35.8 0.0 2.5 2 0 0 2 2 2 1 UBX domain DUF4520 PF15016.6 EKX51590.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) Peptidase_C2 PF00648.21 EKX51591.1 - 3.4e-37 128.1 0.0 2e-16 59.9 0.0 3.1 1 1 2 3 3 3 3 Calpain family cysteine protease Calpain_III PF01067.22 EKX51591.1 - 6e-08 33.1 0.7 0.02 15.2 0.0 3.9 2 2 1 3 3 3 2 Calpain large subunit, domain III ELO PF01151.18 EKX51592.1 - 5.2e-71 239.1 15.9 6.5e-71 238.8 15.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family CytochromB561_N PF09786.9 EKX51592.1 - 0.07 12.1 0.3 0.086 11.8 0.3 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal zf-C2H2_jaz PF12171.8 EKX51593.1 - 0.0019 18.4 0.6 0.0019 18.4 0.6 2.3 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Beta_helix PF13229.6 EKX51594.1 - 8e-34 116.8 19.4 1.9e-16 60.3 7.7 2.9 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 EKX51594.1 - 6.8e-25 87.7 7.6 6.2e-12 45.3 2.5 2.4 2 0 0 2 2 2 2 Periplasmic copper-binding protein (NosD) Tcp11 PF05794.13 EKX51595.1 - 2.4e-42 145.6 0.7 2.4e-42 145.6 0.7 1.8 2 1 0 2 2 2 1 T-complex protein 11 PXA PF02194.15 EKX51595.1 - 0.68 9.9 4.7 0.93 9.4 0.7 2.7 2 1 0 2 2 2 0 PXA domain Tcp11 PF05794.13 EKX51596.1 - 1.8e-43 149.3 0.2 1.8e-43 149.3 0.2 1.8 2 1 0 2 2 2 1 T-complex protein 11 PXA PF02194.15 EKX51596.1 - 0.33 10.9 3.3 0.68 9.9 0.2 2.7 2 1 0 2 2 2 0 PXA domain CHAD PF05235.14 EKX51596.1 - 9.3 6.1 10.5 0.28 11.1 0.4 2.8 2 1 0 2 2 2 0 CHAD domain IQ PF00612.27 EKX51597.1 - 0.0039 16.9 0.2 0.01 15.5 0.2 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif TIG PF01833.24 EKX51598.1 - 9e-15 54.5 27.2 2.6e-05 24.2 0.8 9.8 9 0 0 9 9 9 4 IPT/TIG domain Anth_Ig PF05587.13 EKX51598.1 - 2e-05 24.9 0.1 0.2 12.0 0.0 3.8 3 0 0 3 3 3 2 Anthrax receptor extracellular domain TIG_plexin PF17960.1 EKX51598.1 - 0.0031 17.5 0.6 3 7.9 0.0 3.9 3 0 0 3 3 3 2 TIG domain Inhibitor_I42 PF09394.10 EKX51598.1 - 0.042 14.3 0.0 6 7.4 0.0 4.5 4 0 0 4 4 4 0 Chagasin family peptidase inhibitor I42 Big_2 PF02368.18 EKX51598.1 - 2.8 7.9 7.7 33 4.5 0.4 6.0 6 0 0 6 6 6 0 Bacterial Ig-like domain (group 2) Tcp11 PF05794.13 EKX51599.1 - 2.6e-42 145.5 0.7 2.6e-42 145.5 0.7 1.6 2 0 0 2 2 2 1 T-complex protein 11 PXA PF02194.15 EKX51599.1 - 0.093 12.7 3.6 0.77 9.7 0.5 2.9 2 1 0 2 2 2 0 PXA domain DUF2652 PF10851.8 EKX51600.1 - 0.44 10.7 8.4 0.69 10.0 1.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2652) RNA_capsid PF03035.14 EKX51600.1 - 0.48 10.4 2.5 0.93 9.5 2.5 1.5 1 0 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein Tcp11 PF05794.13 EKX51601.1 - 2.1e-42 145.8 1.1 2.4e-42 145.6 0.2 1.6 2 0 0 2 2 2 1 T-complex protein 11 PXA PF02194.15 EKX51601.1 - 0.095 12.7 2.0 0.51 10.3 0.1 2.7 2 1 0 2 2 2 0 PXA domain PPR_3 PF13812.6 EKX51602.1 - 3.4e-31 107.1 0.9 3.9e-09 36.5 0.1 5.0 5 1 0 5 5 5 4 Pentatricopeptide repeat domain PPR_2 PF13041.6 EKX51602.1 - 1.2e-30 105.4 7.6 3.9e-07 30.2 0.1 5.3 6 0 0 6 6 6 5 PPR repeat family PPR_long PF17177.4 EKX51602.1 - 2.3e-18 66.4 2.7 1.7e-06 27.5 0.1 3.1 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EKX51602.1 - 1.5e-13 50.2 9.4 0.0014 18.3 0.3 6.5 6 0 0 6 6 6 4 PPR repeat PPR PF01535.20 EKX51602.1 - 1.5e-05 24.9 26.6 1.8 9.0 0.0 8.8 10 0 0 10 10 10 3 PPR repeat ECSIT PF06239.11 EKX51602.1 - 0.013 14.6 1.5 17 4.5 0.0 3.6 2 2 1 4 4 4 0 Evolutionarily conserved signalling intermediate in Toll pathway Phage_ABA_S PF18066.1 EKX51602.1 - 0.14 12.9 0.1 26 5.6 0.0 2.6 1 1 1 2 2 2 0 Phage ABA sandwich domain DUF440 PF04269.12 EKX51602.1 - 0.17 12.2 0.4 0.32 11.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF440 FKBP_C PF00254.28 EKX51603.1 - 1.3e-26 92.7 0.0 1.6e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4659 PF15558.6 EKX51604.1 - 0.002 17.1 7.5 0.0029 16.5 3.0 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4659) DUF3584 PF12128.8 EKX51604.1 - 0.0023 15.6 15.3 0.0031 15.1 15.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) SbcD_C PF12320.8 EKX51604.1 - 0.035 14.4 10.7 0.98 9.8 6.1 3.6 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Sbi-IV PF11621.8 EKX51604.1 - 0.054 13.9 22.0 34 4.9 0.2 7.4 2 1 3 7 7 6 0 C3 binding domain 4 of IgG-bind protein SBI Sec2p PF06428.11 EKX51604.1 - 0.075 13.0 19.8 13 5.9 0.8 6.0 2 1 4 6 6 6 0 GDP/GTP exchange factor Sec2p HSDR_N_2 PF13588.6 EKX51604.1 - 0.14 12.1 3.9 3.1 7.8 0.3 2.6 1 1 2 3 3 3 0 Type I restriction enzyme R protein N terminus (HSDR_N) TMF_DNA_bd PF12329.8 EKX51604.1 - 1.7 8.7 12.4 4.7 7.3 0.7 5.0 1 1 5 6 6 6 0 TATA element modulatory factor 1 DNA binding Exonuc_VII_L PF02601.15 EKX51604.1 - 3.8 7.0 12.3 88 2.5 12.3 2.2 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF2968 PF11180.8 EKX51604.1 - 3.8 7.1 12.3 11 5.5 3.6 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) Bac_RepA_C PF18008.1 EKX51604.1 - 6.4 7.2 6.4 16 5.9 0.2 4.1 1 1 5 6 6 6 0 Replication initiator protein A C-terminal domain Phlebovirus_NSM PF07246.11 EKX51604.1 - 7.2 5.9 16.9 1.1 8.6 0.7 3.4 1 1 2 3 3 3 0 Phlebovirus nonstructural protein NS-M Baculo_PEP_C PF04513.12 EKX51604.1 - 7.9 6.5 10.9 52 3.9 3.8 3.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FKBP_C PF00254.28 EKX51605.1 - 6.1e-26 90.6 0.0 1.3e-25 89.6 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PAN_1 PF00024.26 EKX51605.1 - 5.5e-06 26.3 4.1 1e-05 25.4 4.1 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 EKX51605.1 - 1.7e-05 24.6 0.5 3.3e-05 23.7 0.5 1.5 1 0 0 1 1 1 1 PAN domain DUF615 PF04751.14 EKX51605.1 - 0.043 13.8 0.9 0.069 13.1 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF615) Vps62 PF06101.11 EKX51607.1 - 0.19 10.0 0.1 0.29 9.4 0.1 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 62 DUF1350 PF07082.11 EKX51609.1 - 5.2e-39 134.0 0.0 6.4e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1350) Anoctamin PF04547.12 EKX51609.1 - 0.021 13.7 0.0 0.021 13.7 0.0 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Hydrolase_4 PF12146.8 EKX51609.1 - 0.039 13.2 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 HA PF03457.14 EKX51610.1 - 2.4e-23 82.2 6.7 2.8e-11 43.6 2.9 2.2 2 0 0 2 2 2 2 Helicase associated domain Vma12 PF11712.8 EKX51612.1 - 7.2e-15 55.3 0.0 9.2e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase ATPase_gene1 PF09527.10 EKX51612.1 - 0.31 11.2 5.3 0.44 10.8 5.3 1.2 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter TPR_8 PF13181.6 EKX51613.1 - 0.00093 19.2 0.1 0.01 16.0 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX51613.1 - 0.0017 19.0 0.1 0.93 10.5 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX51613.1 - 0.0043 17.1 0.2 0.036 14.2 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat MAS20 PF02064.15 EKX51613.1 - 0.02 15.0 0.8 0.047 13.8 0.8 1.7 1 1 0 1 1 1 0 MAS20 protein import receptor TPR_1 PF00515.28 EKX51613.1 - 0.15 11.9 0.2 0.15 11.9 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF87 PF01935.17 EKX51613.1 - 0.18 11.8 2.5 0.25 11.4 2.5 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain DUF3104 PF11302.8 EKX51614.1 - 0.15 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) DUF4834 PF16118.5 EKX51614.1 - 7.7 7.6 19.1 8 7.5 0.0 4.4 4 1 0 4 4 4 0 Domain of unknown function (DUF4834) CUB PF00431.20 EKX51615.1 - 4.1e-05 23.9 0.0 0.00011 22.5 0.0 1.8 1 1 0 1 1 1 1 CUB domain Pyr_redox_2 PF07992.14 EKX51616.1 - 5.1e-40 137.5 0.2 6e-40 137.3 0.2 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EKX51616.1 - 9.8e-14 51.7 0.6 1.9e-09 38.0 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EKX51616.1 - 5.9e-08 32.8 0.2 0.19 11.7 0.0 3.5 2 2 1 3 3 3 3 FAD-NAD(P)-binding DAO PF01266.24 EKX51616.1 - 1.7e-06 27.9 2.5 0.027 14.1 0.1 3.8 2 2 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EKX51616.1 - 7.9e-06 26.0 0.1 0.068 13.4 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EKX51616.1 - 3.2e-05 23.2 0.0 0.21 10.7 0.0 3.1 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EKX51616.1 - 0.037 12.7 0.7 5.5 5.6 0.0 3.3 4 0 0 4 4 4 0 HI0933-like protein Trp_halogenase PF04820.14 EKX51616.1 - 0.054 12.3 0.2 1.8 7.3 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.14 EKX51616.1 - 0.081 12.5 0.3 8.5 5.9 0.0 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Beta_helix PF13229.6 EKX51617.1 - 0.16 11.9 0.0 3 7.7 0.0 2.0 2 0 0 2 2 2 0 Right handed beta helix region Sushi PF00084.20 EKX51618.1 - 9.8e-12 45.3 9.4 0.0012 19.4 0.3 4.7 4 0 0 4 4 4 3 Sushi repeat (SCR repeat) Arm-DNA-bind_1 PF09003.10 EKX51618.1 - 0.07 13.3 0.2 0.17 12.0 0.2 1.6 1 0 0 1 1 1 0 Bacteriophage lambda integrase, Arm DNA-binding domain PCSK9_C3 PF18463.1 EKX51618.1 - 0.26 11.5 8.9 17 5.7 0.6 4.9 5 0 0 5 5 5 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain Methyltr_RsmB-F PF01189.17 EKX51621.1 - 1.6e-18 67.1 0.0 1.9e-15 57.0 0.1 3.2 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EKX51621.1 - 1e-06 29.1 0.1 1.5e-05 25.4 0.1 2.3 1 1 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF RIO1 PF01163.22 EKX51622.1 - 3.2e-63 212.7 0.0 4.5e-63 212.3 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EKX51622.1 - 0.072 12.4 0.0 0.26 10.6 0.0 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EKX51622.1 - 0.088 12.2 0.0 0.19 11.0 0.0 1.5 1 1 0 1 1 1 0 Protein kinase domain Pkinase_fungal PF17667.1 EKX51622.1 - 0.098 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase RCC1 PF00415.18 EKX51623.1 - 1.2e-39 134.6 17.2 9.3e-14 51.8 0.1 5.4 5 1 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX51623.1 - 1.5e-26 91.5 30.4 1.7e-10 40.4 3.8 4.5 4 1 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat DUF3919 PF13057.6 EKX51624.1 - 0.046 13.3 0.1 0.081 12.5 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3919) DUF1381 PF07129.11 EKX51625.1 - 0.0001 22.0 6.2 3 7.7 0.1 3.6 3 0 0 3 3 3 3 Protein of unknown function (DUF1381) UPF0180 PF03698.13 EKX51625.1 - 0.00037 20.6 0.0 21 5.4 0.0 3.5 3 0 0 3 3 3 3 Uncharacterised protein family (UPF0180) UBM PF14377.6 EKX51625.1 - 0.031 13.7 5.7 18 5.0 0.1 3.6 3 0 0 3 3 3 0 Ubiquitin binding region RraB PF06877.11 EKX51625.1 - 1.1 10.0 4.0 1.9e+02 2.9 0.1 3.7 4 0 0 4 4 4 0 Regulator of ribonuclease activity B Tcp11 PF05794.13 EKX51626.1 - 1.4e-42 146.4 2.2 2.4e-42 145.6 0.3 2.0 2 0 0 2 2 2 1 T-complex protein 11 PXA PF02194.15 EKX51626.1 - 0.29 11.1 2.2 0.61 10.0 0.2 2.4 2 1 0 2 2 2 0 PXA domain DUF4599 PF15371.6 EKX51627.1 - 4.2 8.0 9.7 15 6.2 1.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4599) Atrophin-1 PF03154.15 EKX51627.1 - 6.8 4.8 10.9 6.8 4.8 10.9 1.0 1 0 0 1 1 1 0 Atrophin-1 family SET PF00856.28 EKX51628.1 - 5.4e-10 39.9 0.2 4.6e-09 36.9 0.1 2.3 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.18 EKX51628.1 - 3.5e-08 33.4 13.0 3.5e-08 33.4 13.0 2.1 2 0 0 2 2 2 1 MYND finger EIF_2_alpha PF07541.12 EKX51628.1 - 0.049 13.7 0.0 0.34 11.0 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 2 alpha subunit Nuc_deoxyri_tr3 PF11071.8 EKX51629.1 - 0.013 15.5 0.2 0.039 14.0 0.0 1.9 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase YtoQ ABC_tran_CTD PF16326.5 EKX51629.1 - 0.025 14.8 4.1 0.025 14.8 4.1 2.7 3 0 0 3 3 3 0 ABC transporter C-terminal domain V_ATPase_I PF01496.19 EKX51629.1 - 1.2 6.9 11.5 1.6 6.5 11.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Swi5 PF07061.11 EKX51629.1 - 2.8 8.1 8.0 1.5e+02 2.6 8.0 2.8 1 1 0 1 1 1 0 Swi5 DUF4407 PF14362.6 EKX51629.1 - 3.8 6.8 9.9 4.9 6.4 9.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Anti-adapt_IraP PF10796.9 EKX51629.1 - 5.1 7.7 7.4 6.7 7.3 4.4 2.8 2 1 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein SlyX PF04102.12 EKX51629.1 - 5.8 7.6 11.2 40 4.9 1.3 3.7 2 1 1 3 3 3 0 SlyX Csm1_N PF18504.1 EKX51629.1 - 9.2 6.7 12.8 4.5 7.7 3.9 3.7 2 1 0 3 3 3 0 Csm1 N-terminal domain Bestrophin PF01062.21 EKX51630.1 - 6.4e-15 55.3 1.2 4.6e-14 52.5 1.2 2.3 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DENN PF02141.21 EKX51632.1 - 7e-25 88.1 1.9 9.7e-18 64.8 0.2 2.4 2 0 0 2 2 2 2 DENN (AEX-3) domain dDENN PF03455.19 EKX51632.1 - 3.1e-14 52.7 1.6 8.4e-14 51.3 1.6 1.8 1 0 0 1 1 1 1 dDENN domain PPR_2 PF13041.6 EKX51632.1 - 1.5e-10 41.1 0.0 2.6e-05 24.3 0.0 2.4 1 1 1 2 2 2 2 PPR repeat family uDENN PF03456.18 EKX51632.1 - 2.8e-10 40.8 0.1 8.7e-10 39.2 0.1 1.9 1 0 0 1 1 1 1 uDENN domain PPR_3 PF13812.6 EKX51632.1 - 4e-06 26.8 0.0 5.2e-05 23.2 0.0 2.3 1 1 0 1 1 1 1 Pentatricopeptide repeat domain PPR_long PF17177.4 EKX51632.1 - 5.9e-05 22.5 0.2 0.00014 21.3 0.1 1.6 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EKX51632.1 - 0.00026 21.0 2.0 0.02 15.1 0.0 3.0 3 0 0 3 3 3 1 PPR repeat PPR_1 PF12854.7 EKX51632.1 - 0.0033 17.1 0.0 0.39 10.5 0.0 2.8 3 0 0 3 3 3 1 PPR repeat IBR PF01485.21 EKX51632.1 - 0.042 14.1 1.9 3.6 7.9 0.4 2.8 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain zinc_ribbon_2 PF13240.6 EKX51633.1 - 1.4e-05 24.7 2.3 1.4e-05 24.7 2.3 1.9 2 0 0 2 2 2 1 zinc-ribbon domain DZR PF12773.7 EKX51633.1 - 7.2e-05 22.7 4.5 0.00044 20.2 0.9 2.2 2 0 0 2 2 2 1 Double zinc ribbon zf-ribbon_3 PF13248.6 EKX51633.1 - 0.0017 17.7 2.4 0.0035 16.7 2.4 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DUF2116 PF09889.9 EKX51633.1 - 0.76 9.8 3.0 1.4 9.0 3.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Nudix_N_2 PF14803.6 EKX51633.1 - 2.5 8.1 5.1 30 4.6 0.5 2.8 2 0 0 2 2 2 0 Nudix N-terminal MTP18 PF10558.9 EKX51635.1 - 1.5e-18 67.3 2.1 4.6e-16 59.2 2.1 2.1 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Bromodomain PF00439.25 EKX51636.1 - 2.7e-18 65.8 0.0 3.7e-18 65.4 0.0 1.2 1 1 0 1 1 1 1 Bromodomain Peptidase_S28 PF05577.12 EKX51637.1 - 6.9e-75 252.5 0.0 8.7e-75 252.1 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 EKX51637.1 - 3e-05 23.6 0.0 5.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EKX51637.1 - 8.8e-05 22.3 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EKX51637.1 - 0.00069 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S37 PF05576.11 EKX51637.1 - 0.0009 18.0 0.3 0.0026 16.5 0.1 1.7 2 0 0 2 2 2 1 PS-10 peptidase S37 Abhydrolase_6 PF12697.7 EKX51637.1 - 0.0017 19.0 0.3 0.0066 17.1 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family PAP2 PF01569.21 EKX51638.1 - 3.8e-08 33.2 11.2 4.1e-08 33.1 8.2 2.4 1 1 0 2 2 2 1 PAP2 superfamily Dpy19 PF10034.9 EKX51638.1 - 0.0018 16.5 0.1 0.0031 15.8 0.0 1.4 1 1 0 1 1 1 1 Q-cell neuroblast polarisation DUF212 PF02681.14 EKX51638.1 - 0.015 15.4 0.5 0.37 10.9 0.1 2.3 1 1 1 2 2 2 0 Divergent PAP2 family DUF1899 PF08953.11 EKX51639.1 - 3.1e-26 91.0 0.0 5.6e-26 90.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 EKX51639.1 - 5.2e-17 61.5 0.0 9.2e-17 60.7 0.0 1.4 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 EKX51639.1 - 1.6e-11 44.6 0.9 0.0015 19.3 0.0 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX51639.1 - 4.8e-05 23.6 0.0 0.018 15.3 0.2 3.8 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain bZIP_1 PF00170.21 EKX51639.1 - 0.01 15.9 4.3 0.019 15.1 4.0 1.7 1 1 0 1 1 1 0 bZIP transcription factor DUF3450 PF11932.8 EKX51639.1 - 0.061 12.6 0.3 0.09 12.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Nup160 PF11715.8 EKX51639.1 - 0.077 11.6 0.1 0.19 10.3 0.1 1.4 1 1 0 1 1 1 0 Nucleoporin Nup120/160 TSC22 PF01166.18 EKX51639.1 - 0.14 12.5 1.8 0.24 11.8 1.1 1.8 1 1 0 1 1 1 0 TSC-22/dip/bun family Thump_like PF18096.1 EKX51639.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 THUMP domain-like BLOC1_2 PF10046.9 EKX51639.1 - 0.25 11.7 5.9 0.06 13.6 2.6 1.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ZapB PF06005.12 EKX51639.1 - 0.32 11.5 6.2 0.52 10.8 6.2 1.3 1 0 0 1 1 1 0 Cell division protein ZapB Phage_lysis PF03245.13 EKX51639.1 - 0.7 10.0 3.6 1.4 9.1 3.6 1.4 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein bZIP_2 PF07716.15 EKX51639.1 - 0.94 9.6 10.7 0.4 10.8 3.3 2.2 1 1 1 2 2 2 0 Basic region leucine zipper DivIC PF04977.15 EKX51639.1 - 7.3 6.4 8.0 4.5 7.1 3.2 2.3 1 1 1 2 2 2 0 Septum formation initiator P2X_receptor PF00864.19 EKX51641.1 - 8e-17 61.4 0.1 1.1e-07 31.3 0.0 2.1 2 0 0 2 2 2 2 ATP P2X receptor Macoilin PF09726.9 EKX51642.1 - 7.6 5.0 8.5 13 4.2 8.5 1.3 1 0 0 1 1 1 0 Macoilin family NTPase_1 PF03266.15 EKX51644.1 - 3.2e-37 128.0 0.1 3.9e-37 127.8 0.1 1.0 1 0 0 1 1 1 1 NTPase ATPase_2 PF01637.18 EKX51644.1 - 0.00027 20.9 0.0 0.00033 20.6 0.0 1.4 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea Rad17 PF03215.15 EKX51644.1 - 0.00039 20.4 0.0 0.00098 19.1 0.0 1.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_17 PF13207.6 EKX51644.1 - 0.00084 19.8 0.1 0.001 19.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EKX51644.1 - 0.0014 18.7 0.2 0.02 14.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EKX51644.1 - 0.0034 17.7 0.0 0.0052 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EKX51644.1 - 0.0047 17.2 0.0 0.0074 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EKX51644.1 - 0.0079 16.6 0.0 0.011 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 EKX51644.1 - 0.0096 16.0 0.0 0.01 15.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Zeta_toxin PF06414.12 EKX51644.1 - 0.013 14.8 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.29 EKX51644.1 - 0.016 15.7 0.0 0.019 15.4 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EKX51644.1 - 0.034 14.3 0.0 0.038 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 EKX51644.1 - 0.038 13.9 0.1 0.11 12.3 0.0 1.8 2 1 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 EKX51644.1 - 0.039 13.7 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 EKX51644.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ploopntkinase3 PF18751.1 EKX51644.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Arf PF00025.21 EKX51644.1 - 0.13 11.7 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family NB-ARC PF00931.22 EKX51644.1 - 0.15 11.2 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 EKX51644.1 - 0.16 12.3 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase cobW PF02492.19 EKX51644.1 - 0.22 11.1 0.0 0.41 10.2 0.0 1.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GGA_N-GAT PF18308.1 EKX51644.1 - 0.24 11.0 0.0 0.82 9.3 0.0 1.8 2 0 0 2 2 2 0 GGA N-GAT domain FlaC_arch PF05377.11 EKX51645.1 - 0.00037 20.8 3.5 0.13 12.7 0.3 2.3 2 0 0 2 2 2 2 Flagella accessory protein C (FlaC) GAS PF13851.6 EKX51645.1 - 0.001 18.5 4.5 0.0013 18.1 4.5 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Macoilin PF09726.9 EKX51645.1 - 0.0021 16.7 2.9 0.0024 16.5 2.9 1.0 1 0 0 1 1 1 1 Macoilin family SlyX PF04102.12 EKX51645.1 - 0.0037 17.8 1.8 1.5 9.5 0.4 2.1 2 0 0 2 2 2 2 SlyX TMF_DNA_bd PF12329.8 EKX51645.1 - 0.0068 16.4 7.9 0.13 12.3 1.1 2.1 2 0 0 2 2 2 2 TATA element modulatory factor 1 DNA binding APG6_N PF17675.1 EKX51645.1 - 0.015 15.8 5.8 0.021 15.4 5.8 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Fez1 PF06818.15 EKX51645.1 - 0.018 15.5 3.1 0.022 15.2 3.1 1.1 1 0 0 1 1 1 0 Fez1 bZIP_1 PF00170.21 EKX51645.1 - 0.019 15.1 5.2 0.038 14.1 0.8 2.2 2 0 0 2 2 2 0 bZIP transcription factor Cep57_CLD_2 PF14197.6 EKX51645.1 - 0.021 14.9 8.8 0.52 10.4 2.2 2.0 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 DivIC PF04977.15 EKX51645.1 - 0.048 13.4 5.1 0.36 10.6 0.7 2.1 2 0 0 2 2 2 0 Septum formation initiator TSC22 PF01166.18 EKX51645.1 - 0.051 13.9 2.8 1.9 8.8 0.2 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family Tropomyosin_1 PF12718.7 EKX51645.1 - 0.061 13.5 8.5 0.12 12.5 8.5 1.4 1 1 0 1 1 1 0 Tropomyosin like bZIP_2 PF07716.15 EKX51645.1 - 0.061 13.4 6.1 0.082 13.0 1.8 2.1 2 0 0 2 2 2 0 Basic region leucine zipper Allexi_40kDa PF05549.11 EKX51645.1 - 0.069 12.7 1.8 0.074 12.6 1.8 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF1192 PF06698.11 EKX51645.1 - 0.11 12.5 3.4 1.1 9.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) SOGA PF11365.8 EKX51645.1 - 0.12 13.5 7.3 0.68 11.1 1.6 2.1 1 1 0 2 2 2 0 Protein SOGA PRKG1_interact PF15898.5 EKX51645.1 - 0.13 13.1 7.5 0.25 12.2 7.5 1.5 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain HAP1_N PF04849.13 EKX51645.1 - 0.15 11.2 6.2 0.31 10.2 6.2 1.5 1 1 0 1 1 1 0 HAP1 N-terminal conserved region CSN5_C PF18323.1 EKX51645.1 - 0.19 12.6 4.2 0.37 11.7 4.2 1.6 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain DUF724 PF05266.14 EKX51645.1 - 0.28 11.0 4.7 0.35 10.7 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Swi5 PF07061.11 EKX51645.1 - 0.6 10.2 4.2 12 6.1 0.3 2.1 2 0 0 2 2 2 0 Swi5 PKcGMP_CC PF16808.5 EKX51645.1 - 0.7 9.8 5.8 0.25 11.2 0.7 2.2 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase HIP1_clath_bdg PF16515.5 EKX51645.1 - 0.84 10.3 9.3 1.3 9.7 4.7 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CCDC-167 PF15188.6 EKX51645.1 - 1.2 9.5 7.3 2.2 8.7 7.3 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 FAM76 PF16046.5 EKX51645.1 - 1.3 8.4 4.8 1.6 8.0 4.8 1.2 1 0 0 1 1 1 0 FAM76 protein DUF4140 PF13600.6 EKX51645.1 - 4.6 7.7 6.4 11 6.5 0.8 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) CLAMP PF14769.6 EKX51646.1 - 4.2e-28 97.7 3.1 5.9e-28 97.2 3.1 1.2 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 AAA_28 PF13521.6 EKX51647.1 - 1.9e-09 38.0 0.0 7.8e-09 36.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain T2SS-T3SS_pil_N PF13629.6 EKX51647.1 - 0.084 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Pilus formation protein N terminal region Atg14 PF10186.9 EKX51648.1 - 4.8 6.2 9.5 0.28 10.2 3.1 1.7 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Kelch_5 PF13854.6 EKX51649.1 - 6.7e-08 32.3 11.0 5.2e-05 23.1 0.0 4.8 4 2 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 EKX51649.1 - 0.00017 21.8 5.1 0.014 15.7 0.0 3.8 4 1 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 EKX51649.1 - 0.00052 19.5 3.6 0.75 9.4 0.1 4.2 4 1 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 EKX51649.1 - 0.13 12.6 20.7 0.17 12.2 0.6 5.0 4 3 0 4 4 4 0 Galactose oxidase, central domain DNA_pol_B PF00136.21 EKX51650.1 - 4.6e-142 473.9 0.0 6.5e-142 473.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EKX51650.1 - 1.1e-77 261.5 0.4 1.6e-77 261.0 0.4 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EKX51650.1 - 2.1e-17 63.3 7.2 5.2e-17 62.1 7.2 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 EKX51650.1 - 0.00028 19.9 0.0 0.00049 19.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_A_exo1 PF01612.20 EKX51650.1 - 0.055 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 3'-5' exonuclease DZR PF12773.7 EKX51650.1 - 8.9 6.4 6.4 1.4 9.0 0.6 2.2 2 0 0 2 2 2 0 Double zinc ribbon Ank_4 PF13637.6 EKX51651.1 - 4.1e-19 68.7 3.4 2.3e-12 47.2 0.5 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX51651.1 - 3.5e-16 58.8 1.4 1.7e-08 34.5 0.1 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EKX51651.1 - 2.8e-15 56.2 5.8 3.4e-11 43.2 1.6 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX51651.1 - 1.8e-14 54.0 1.0 7.2e-10 39.3 0.1 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX51651.1 - 2.2e-14 52.1 0.9 8e-08 32.0 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat PDZ_2 PF13180.6 EKX51653.1 - 0.0048 17.2 0.2 0.025 14.9 0.1 2.3 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EKX51653.1 - 0.0068 16.2 0.2 0.026 14.4 0.1 2.0 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX51653.1 - 0.053 13.9 0.4 0.21 12.0 0.1 2.2 2 0 0 2 2 2 0 PDZ domain Polysacc_deac_1 PF01522.21 EKX51653.1 - 0.095 12.6 2.0 0.1 12.5 0.0 2.0 3 0 0 3 3 3 0 Polysaccharide deacetylase SNF2_N PF00176.23 EKX51654.1 - 3.3e-77 259.6 0.0 4.8e-77 259.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX51654.1 - 2.5e-17 63.2 0.0 9.6e-17 61.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HIRAN PF08797.11 EKX51654.1 - 5.2e-14 52.0 0.0 1.1e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain zf-RING_2 PF13639.6 EKX51654.1 - 1.6e-06 28.4 15.6 1.6e-06 28.4 15.6 2.6 2 0 0 2 2 2 1 Ring finger domain DEAD PF00270.29 EKX51654.1 - 1.9e-05 24.5 0.0 4.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_UBOX PF13445.6 EKX51654.1 - 0.0001 22.2 7.5 0.0001 22.2 7.5 2.4 2 1 1 3 3 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EKX51654.1 - 0.0012 18.7 16.0 0.0038 17.0 16.0 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX51654.1 - 0.0017 18.2 15.5 0.0045 16.8 15.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ERCC3_RAD25_C PF16203.5 EKX51654.1 - 0.0034 16.6 0.1 0.0064 15.7 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-PARP PF00645.18 EKX51654.1 - 0.0041 18.0 0.1 0.012 16.4 0.1 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-RING_5 PF14634.6 EKX51654.1 - 0.014 15.3 14.7 0.034 14.1 14.7 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 EKX51654.1 - 0.029 14.2 12.0 0.075 12.8 12.0 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Med9 PF07544.13 EKX51654.1 - 0.056 13.5 0.2 0.33 11.1 0.2 2.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF2559 PF10832.8 EKX51654.1 - 0.075 13.1 2.4 2.1 8.5 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2559) Flavi_capsid PF01003.19 EKX51654.1 - 0.11 12.3 0.1 0.39 10.5 0.0 2.0 2 0 0 2 2 2 0 Flavivirus capsid protein C zf-ANAPC11 PF12861.7 EKX51654.1 - 0.64 10.1 11.5 0.053 13.6 4.7 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EKX51654.1 - 0.85 9.5 17.7 0.19 11.6 13.5 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EKX51654.1 - 2 8.7 17.1 8.4 6.7 17.2 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EKX51654.1 - 3.2 8.1 20.0 0.39 11.0 9.1 3.1 3 0 0 3 3 2 0 RING-H2 zinc finger domain Beta_helix PF13229.6 EKX51655.1 - 8.6e-54 181.7 53.2 3.3e-22 79.0 8.9 4.7 1 1 4 5 5 5 5 Right handed beta helix region NosD PF05048.13 EKX51655.1 - 8.3e-37 126.7 19.6 1.2e-12 47.7 1.8 4.1 1 1 3 4 4 4 4 Periplasmic copper-binding protein (NosD) Disaggr_assoc PF08480.10 EKX51655.1 - 0.11 12.4 17.1 0.12 12.2 0.6 4.7 2 2 2 4 4 4 0 Disaggregatase related Pectate_lyase_3 PF12708.7 EKX51655.1 - 0.12 12.1 18.8 0.64 9.8 2.0 4.0 1 1 3 4 4 4 0 Pectate lyase superfamily protein Ten1_2 PF15490.6 EKX51656.1 - 1.9e-20 72.7 0.0 2.2e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit DUF3471 PF11954.8 EKX51656.1 - 0.018 15.5 0.0 0.039 14.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3471) Asp PF00026.23 EKX51659.1 - 3.2e-30 105.6 0.0 6.2e-20 71.8 0.0 2.7 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EKX51659.1 - 3e-08 34.1 0.0 0.00027 21.2 0.0 2.4 2 0 0 2 2 2 2 Xylanase inhibitor N-terminal CobU PF02283.16 EKX51660.1 - 1.2e-08 34.7 33.5 6.4 6.3 0.2 10.3 4 3 6 11 11 11 10 Cobinamide kinase / cobinamide phosphate guanyltransferase Glutaredoxin PF00462.24 EKX51660.1 - 0.81 9.9 9.1 6.7e+02 0.6 0.0 8.5 11 0 0 11 11 11 0 Glutaredoxin bHLH-MYC_N PF14215.6 EKX51660.1 - 6.5 7.0 52.3 51 4.1 0.2 10.8 11 0 0 11 11 11 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal Vps52 PF04129.12 EKX51662.1 - 2.7e-56 191.4 5.6 1.8e-55 188.6 5.6 1.9 1 1 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 EKX51662.1 - 1.1e-15 57.1 6.0 4e-15 55.3 6.0 1.9 1 1 0 1 1 1 1 Exocyst complex component Sec3 COG2 PF06148.11 EKX51662.1 - 0.014 15.4 6.6 0.57 10.3 0.1 3.6 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2018 PF09442.10 EKX51662.1 - 0.11 13.5 0.7 0.88 10.6 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF2018) DUF2894 PF11445.8 EKX51662.1 - 0.12 12.8 0.5 0.3 11.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) SlyX PF04102.12 EKX51663.1 - 0.0099 16.5 7.5 0.21 12.3 1.2 3.2 3 0 0 3 3 3 1 SlyX HhH-GPD PF00730.25 EKX51663.1 - 0.017 15.6 0.4 0.087 13.3 0.1 2.2 2 0 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein GAS PF13851.6 EKX51663.1 - 0.045 13.1 13.3 0.7 9.2 5.8 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1565 PF07602.11 EKX51663.1 - 0.094 12.0 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) T3SSipB PF16535.5 EKX51663.1 - 0.26 11.7 3.8 8.3 6.9 0.3 2.3 2 0 0 2 2 2 0 Type III cell invasion protein SipB DUF812 PF05667.11 EKX51663.1 - 0.71 8.7 16.8 2.1 7.1 7.6 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF812) CLZ PF16526.5 EKX51663.1 - 0.89 10.0 11.3 0.27 11.6 3.3 3.3 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fib_alpha PF08702.10 EKX51663.1 - 1.6 8.9 6.9 1.3 9.2 1.2 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.9 EKX51663.1 - 2.3 8.2 19.8 0.3 11.1 1.7 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 EKX51663.1 - 3 7.1 6.2 6.6 6.0 6.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 EKX51663.1 - 3.1 7.8 7.1 7.9 6.5 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2203 PF09969.9 EKX51663.1 - 3.4 8.4 7.5 3.1 8.5 2.6 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF2730 PF10805.8 EKX51663.1 - 3.9 7.6 5.7 15 5.7 1.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) Csm1_N PF18504.1 EKX51663.1 - 4.6 7.7 12.9 1.5 9.2 0.6 3.4 2 2 1 3 3 3 0 Csm1 N-terminal domain DegS PF05384.11 EKX51663.1 - 5.5 6.5 14.3 23 4.4 14.3 2.0 1 1 0 1 1 1 0 Sensor protein DegS Jnk-SapK_ap_N PF09744.9 EKX51663.1 - 6.4 7.0 18.9 10 6.3 1.7 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 BLOC1_2 PF10046.9 EKX51663.1 - 7.8 6.9 10.9 1.1 9.6 0.9 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 XhlA PF10779.9 EKX51663.1 - 9.3 6.5 10.8 21 5.4 0.5 3.0 2 0 0 2 2 2 0 Haemolysin XhlA Pkinase PF00069.25 EKX51664.1 - 2.9e-68 230.1 0.0 3.3e-68 229.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX51664.1 - 3.1e-51 174.2 0.0 3.7e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX51664.1 - 7.9e-07 28.2 0.0 1.4e-06 27.3 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EKX51664.1 - 0.00026 20.4 0.0 0.079 12.3 0.0 2.3 2 1 0 2 2 2 2 Kinase-like ABC1 PF03109.16 EKX51664.1 - 0.031 14.4 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Abi_2 PF07751.11 EKX51664.1 - 0.11 12.8 0.0 2.3 8.4 0.0 2.1 1 1 1 2 2 2 0 Abi-like protein Glyco_transf_92 PF01697.27 EKX51666.1 - 1.2e-18 67.7 1.3 2.4e-18 66.7 1.3 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 EKX51666.1 - 0.00014 22.3 0.1 0.00054 20.4 0.1 2.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 RNase_T PF00929.24 EKX51667.1 - 0.00018 22.1 0.0 0.00044 20.8 0.0 1.6 1 1 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EKX51667.1 - 0.043 13.5 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 3'-5' exonuclease Rubis-subs-bind PF09273.11 EKX51668.1 - 0.00022 21.9 0.0 0.00043 21.0 0.0 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 EKX51668.1 - 0.0004 20.8 0.0 0.0012 19.2 0.0 1.9 1 1 0 1 1 1 1 SET domain ABC_tran_CTD PF16326.5 EKX51669.1 - 0.0094 16.2 4.6 0.0094 16.2 4.6 3.7 2 2 1 3 3 3 1 ABC transporter C-terminal domain TSC22 PF01166.18 EKX51669.1 - 0.016 15.5 0.7 0.016 15.5 0.7 3.1 3 0 0 3 3 2 0 TSC-22/dip/bun family WEMBL PF05701.11 EKX51669.1 - 0.017 13.8 17.0 0.31 9.7 17.0 2.1 1 1 0 1 1 1 0 Weak chloroplast movement under blue light MIP-T3_C PF17749.1 EKX51669.1 - 0.018 15.0 3.6 0.018 15.0 3.6 2.7 2 1 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Jnk-SapK_ap_N PF09744.9 EKX51669.1 - 0.027 14.7 27.9 0.22 11.8 15.5 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Spc7 PF08317.11 EKX51669.1 - 0.052 12.4 22.4 0.093 11.6 22.1 1.5 1 1 1 2 2 2 0 Spc7 kinetochore protein Gon7 PF08738.10 EKX51669.1 - 0.091 12.9 2.1 0.11 12.7 1.3 1.5 1 1 0 1 1 1 0 Gon7 family TrkA_N PF02254.18 EKX51669.1 - 0.11 12.8 0.2 5.3 7.3 0.3 2.4 2 0 0 2 2 2 0 TrkA-N domain DUF1664 PF07889.12 EKX51669.1 - 0.14 12.2 11.7 0.17 11.9 4.2 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) HMMR_N PF15905.5 EKX51669.1 - 0.16 11.4 21.3 0.31 10.5 21.3 1.4 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal PRKG1_interact PF15898.5 EKX51669.1 - 0.21 12.5 24.4 0.85 10.5 13.2 2.6 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF4600 PF15372.6 EKX51669.1 - 0.32 11.4 13.8 0.047 14.1 8.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) CEP63 PF17045.5 EKX51669.1 - 0.33 10.8 28.8 0.61 9.9 5.6 2.7 1 1 2 3 3 3 0 Centrosomal protein of 63 kDa KASH_CCD PF14662.6 EKX51669.1 - 0.34 10.7 25.2 0.051 13.4 19.8 2.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH BST2 PF16716.5 EKX51669.1 - 0.48 11.0 14.0 0.16 12.6 3.2 3.0 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 GAS PF13851.6 EKX51669.1 - 0.69 9.2 22.3 0.39 10.0 10.8 2.3 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 EKX51669.1 - 0.77 9.9 8.3 7.6 6.7 3.8 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4239 PF14023.6 EKX51669.1 - 1 9.1 2.9 1.3 8.7 2.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) Plk4_PB2 PF18409.1 EKX51669.1 - 1.1 10.0 6.0 7.1 7.4 0.7 2.2 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 PIN_8 PF18476.1 EKX51669.1 - 1.3 8.8 10.8 4.6 7.0 10.9 1.8 1 1 0 1 1 1 0 PIN like domain Noelin-1 PF12308.8 EKX51669.1 - 1.3 9.0 6.5 2 8.4 3.8 2.3 2 0 0 2 2 2 0 Neurogenesis glycoprotein SPICE PF15678.5 EKX51669.1 - 1.5 8.1 16.4 2.1 7.6 16.4 1.2 1 0 0 1 1 1 0 Centriole duplication and mitotic chromosome congression Laminin_II PF06009.12 EKX51669.1 - 2 8.4 9.3 7.8 6.5 3.9 2.4 1 1 0 2 2 2 0 Laminin Domain II ARA70 PF12489.8 EKX51669.1 - 2.3 8.4 6.8 1.1 9.5 4.2 1.8 1 1 1 2 2 2 0 Nuclear coactivator Prominin PF05478.11 EKX51669.1 - 2.6 5.9 7.3 0.46 8.4 3.1 1.6 1 1 1 2 2 2 0 Prominin TMPIT PF07851.13 EKX51669.1 - 3.1 7.0 12.7 1.7 7.8 4.6 2.0 1 1 1 2 2 2 0 TMPIT-like protein HALZ PF02183.18 EKX51669.1 - 3.1 8.1 11.3 9 6.6 0.3 3.6 3 1 0 3 3 3 0 Homeobox associated leucine zipper DUF724 PF05266.14 EKX51669.1 - 6 6.7 17.8 5 6.9 7.2 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF724) DUF4337 PF14235.6 EKX51669.1 - 6.6 6.8 14.3 0.55 10.3 3.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) FUSC PF04632.12 EKX51669.1 - 6.9 5.1 7.1 8.6 4.7 7.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3450 PF11932.8 EKX51669.1 - 7.5 5.8 18.3 2.6 7.3 6.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Csm1_N PF18504.1 EKX51669.1 - 8.4 6.8 20.8 5.1 7.5 1.4 4.0 2 2 1 3 3 3 0 Csm1 N-terminal domain LapA_dom PF06305.11 EKX51669.1 - 8.9 6.2 10.1 8.5 6.3 0.3 3.5 3 1 0 3 3 3 0 Lipopolysaccharide assembly protein A domain RabGAP-TBC PF00566.18 EKX51670.1 - 1.8e-12 47.3 0.2 2.3e-12 47.0 0.2 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SepQ PF06622.11 EKX51670.1 - 0.041 13.0 0.0 0.041 13.0 0.0 1.1 1 0 0 1 1 1 0 SepQ protein DUF1664 PF07889.12 EKX51672.1 - 1.2e-06 28.5 2.5 1.7e-06 28.1 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DUF812 PF05667.11 EKX51672.1 - 2.5e-05 23.4 0.0 2.5e-05 23.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) LPP PF04728.13 EKX51672.1 - 6.9e-05 23.2 0.4 0.012 15.9 0.0 1.8 1 1 1 2 2 2 2 Lipoprotein leucine-zipper Sipho_Gp157 PF05565.11 EKX51672.1 - 0.00047 20.2 1.0 0.0007 19.6 1.0 1.2 1 0 0 1 1 1 1 Siphovirus Gp157 DUF5082 PF16888.5 EKX51672.1 - 0.00057 20.2 1.3 0.00096 19.4 0.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF5082) Prefoldin_2 PF01920.20 EKX51672.1 - 0.0013 18.7 1.5 0.0019 18.1 1.5 1.3 1 0 0 1 1 1 1 Prefoldin subunit Seryl_tRNA_N PF02403.22 EKX51672.1 - 0.0016 18.6 0.9 0.0023 18.1 0.9 1.2 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain AAA_13 PF13166.6 EKX51672.1 - 0.0026 16.5 1.1 0.003 16.3 1.1 1.0 1 0 0 1 1 1 1 AAA domain CC2-LZ PF16516.5 EKX51672.1 - 0.0029 17.9 1.9 0.0045 17.3 1.9 1.2 1 0 0 1 1 1 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Spc7 PF08317.11 EKX51672.1 - 0.0031 16.5 1.2 0.0042 16.0 1.2 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein XhlA PF10779.9 EKX51672.1 - 0.0033 17.6 3.4 0.0056 16.9 3.4 1.3 1 0 0 1 1 1 1 Haemolysin XhlA bZIP_1 PF00170.21 EKX51672.1 - 0.0045 17.0 0.6 0.0072 16.4 0.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor EzrA PF06160.12 EKX51672.1 - 0.0048 15.1 1.5 0.0059 14.8 1.5 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.9 EKX51672.1 - 0.007 16.4 1.2 0.0098 15.9 1.2 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.15 EKX51672.1 - 0.0078 16.0 0.7 0.013 15.2 0.7 1.4 1 1 0 1 1 1 1 Septum formation initiator Phage_GP20 PF06810.11 EKX51672.1 - 0.0095 15.7 0.4 0.013 15.3 0.4 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 DUF2730 PF10805.8 EKX51672.1 - 0.011 15.9 0.5 0.019 15.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Syntaxin PF00804.25 EKX51672.1 - 0.012 15.3 2.1 0.015 15.0 2.1 1.1 1 0 0 1 1 1 0 Syntaxin YkyA PF10368.9 EKX51672.1 - 0.012 15.3 1.9 0.017 14.8 1.9 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein DUF4618 PF15397.6 EKX51672.1 - 0.013 15.0 0.7 0.018 14.5 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) YabA PF06156.13 EKX51672.1 - 0.013 16.1 0.5 0.022 15.4 0.5 1.4 1 0 0 1 1 1 0 Initiation control protein YabA FlaC_arch PF05377.11 EKX51672.1 - 0.014 15.8 5.3 0.028 14.8 4.9 1.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Phage_HK97_TLTM PF06120.11 EKX51672.1 - 0.015 14.5 1.2 0.018 14.2 1.2 1.1 1 0 0 1 1 1 0 Tail length tape measure protein Fib_alpha PF08702.10 EKX51672.1 - 0.016 15.4 0.9 0.024 14.8 0.9 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Ran-binding PF05508.11 EKX51672.1 - 0.017 14.1 0.8 0.022 13.8 0.8 1.1 1 0 0 1 1 1 0 RanGTP-binding protein GAS PF13851.6 EKX51672.1 - 0.019 14.3 2.4 0.029 13.7 2.4 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF16 PF01519.16 EKX51672.1 - 0.02 15.3 0.9 0.03 14.8 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Filament PF00038.21 EKX51672.1 - 0.022 14.4 0.5 0.028 14.0 0.5 1.1 1 0 0 1 1 1 0 Intermediate filament protein Snapin_Pallidin PF14712.6 EKX51672.1 - 0.024 15.1 1.1 0.041 14.3 1.1 1.3 1 0 0 1 1 1 0 Snapin/Pallidin Tup_N PF08581.10 EKX51672.1 - 0.025 14.9 1.2 0.046 14.0 1.2 1.4 1 0 0 1 1 1 0 Tup N-terminal BLOC1_2 PF10046.9 EKX51672.1 - 0.026 14.8 1.0 0.039 14.2 1.0 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3450 PF11932.8 EKX51672.1 - 0.026 13.8 0.3 0.036 13.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Fmp27_WPPW PF10359.9 EKX51672.1 - 0.029 13.2 0.2 0.034 13.0 0.2 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Bacillus_HBL PF05791.11 EKX51672.1 - 0.029 14.2 0.2 0.041 13.7 0.2 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF641 PF04859.12 EKX51672.1 - 0.032 14.6 0.0 0.042 14.2 0.0 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) zf-C4H2 PF10146.9 EKX51672.1 - 0.033 14.5 1.9 0.048 14.0 1.9 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein DUF2203 PF09969.9 EKX51672.1 - 0.034 14.9 0.4 0.051 14.3 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) AKNA PF12443.8 EKX51672.1 - 0.036 14.7 0.3 0.053 14.2 0.3 1.3 1 0 0 1 1 1 0 AT-hook-containing transcription factor Cauli_AT PF03233.13 EKX51672.1 - 0.036 14.0 0.2 0.043 13.7 0.2 1.2 1 0 0 1 1 1 0 Aphid transmission protein KxDL PF10241.9 EKX51672.1 - 0.037 14.3 0.5 0.065 13.5 0.5 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein BST2 PF16716.5 EKX51672.1 - 0.038 14.6 0.2 0.061 13.9 0.2 1.4 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 CHDCT2 PF08074.11 EKX51672.1 - 0.043 14.0 0.3 4.6 7.4 0.0 2.1 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain TPR_MLP1_2 PF07926.12 EKX51672.1 - 0.044 13.8 0.2 0.062 13.4 0.2 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Fzo_mitofusin PF04799.13 EKX51672.1 - 0.044 13.3 0.6 0.083 12.4 0.6 1.4 1 0 0 1 1 1 0 fzo-like conserved region SKA2 PF16740.5 EKX51672.1 - 0.045 13.5 1.0 0.1 12.4 1.0 1.6 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 TMPIT PF07851.13 EKX51672.1 - 0.048 12.9 0.7 0.065 12.5 0.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein Tektin PF03148.14 EKX51672.1 - 0.049 12.4 1.8 0.059 12.1 1.8 1.1 1 0 0 1 1 1 0 Tektin family DUF1640 PF07798.11 EKX51672.1 - 0.052 13.6 2.8 0.071 13.2 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) NPV_P10 PF05531.12 EKX51672.1 - 0.053 14.0 0.6 0.099 13.1 0.6 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Vps51 PF08700.11 EKX51672.1 - 0.054 13.6 2.9 0.42 10.7 2.9 2.2 1 1 0 1 1 1 0 Vps51/Vps67 HIP1_clath_bdg PF16515.5 EKX51672.1 - 0.058 14.0 0.5 0.096 13.3 0.5 1.3 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 V-SNARE PF05008.15 EKX51672.1 - 0.059 13.8 0.5 0.11 12.9 0.5 1.4 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus DUF1192 PF06698.11 EKX51672.1 - 0.061 13.4 1.0 0.12 12.4 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Prominin PF05478.11 EKX51672.1 - 0.062 11.2 0.2 0.1 10.6 0.2 1.2 1 0 0 1 1 1 0 Prominin Atg14 PF10186.9 EKX51672.1 - 0.073 12.1 0.8 0.09 11.9 0.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 COMP PF11598.8 EKX51672.1 - 0.074 13.5 2.6 0.48 10.9 0.5 2.4 1 1 1 2 2 2 0 Cartilage oligomeric matrix protein DUF4200 PF13863.6 EKX51672.1 - 0.077 13.4 5.3 0.17 12.3 5.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) COG2 PF06148.11 EKX51672.1 - 0.096 12.8 0.5 0.15 12.1 0.5 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 ZapB PF06005.12 EKX51672.1 - 0.099 13.1 2.0 0.21 12.1 2.0 1.6 1 1 0 1 1 1 0 Cell division protein ZapB USP8_interact PF08941.10 EKX51672.1 - 0.1 12.4 0.8 0.14 11.9 0.8 1.2 1 0 0 1 1 1 0 USP8 interacting DUF3375 PF11855.8 EKX51672.1 - 0.11 11.3 0.1 0.15 11.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) DUF948 PF06103.11 EKX51672.1 - 0.13 12.5 0.4 0.2 11.9 0.4 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) TolA_bind_tri PF16331.5 EKX51672.1 - 0.15 12.2 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation Img2 PF05046.14 EKX51672.1 - 0.15 12.4 0.9 0.64 10.4 0.4 2.0 1 1 1 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) ATG16 PF08614.11 EKX51672.1 - 0.15 12.2 1.1 0.22 11.7 1.1 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Cep57_MT_bd PF06657.13 EKX51672.1 - 0.17 12.3 2.8 0.61 10.6 0.8 2.4 2 1 1 3 3 2 0 Centrosome microtubule-binding domain of Cep57 Med4 PF10018.9 EKX51672.1 - 0.18 11.5 1.3 0.23 11.1 1.3 1.1 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Bap31_Bap29_C PF18035.1 EKX51672.1 - 2.1 8.4 5.9 7.6 6.6 5.9 2.0 1 1 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Mito_fiss_reg PF05308.11 EKX51673.1 - 0.27 11.3 0.9 0.66 10.0 0.9 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator LRR_4 PF12799.7 EKX51674.1 - 1.1e-20 73.3 11.2 5.1e-07 29.9 0.2 4.8 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX51674.1 - 5.2e-14 52.1 3.7 7.9e-07 28.7 1.0 3.5 1 1 3 4 4 4 4 Leucine-rich repeat LRR_8 PF13855.6 EKX51674.1 - 1e-13 50.8 10.3 0.00013 21.6 0.1 4.1 3 1 2 5 5 5 4 Leucine rich repeat LRR_1 PF00560.33 EKX51674.1 - 0.00047 20.3 12.2 4.8 8.1 0.0 6.5 7 0 0 7 7 7 2 Leucine Rich Repeat DUF5126 PF17166.4 EKX51674.1 - 0.12 12.2 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5126) LRR_6 PF13516.6 EKX51674.1 - 0.13 12.3 14.6 0.52 10.5 0.1 6.2 7 0 0 7 7 7 0 Leucine Rich repeat DUF747 PF05346.11 EKX51675.1 - 2e-86 290.4 16.5 2.9e-86 289.8 16.5 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family YfdX PF10938.8 EKX51677.1 - 0.0011 18.9 0.3 0.26 11.2 0.1 2.6 2 0 0 2 2 2 2 YfdX protein Pirin_C PF05726.13 EKX51677.1 - 0.38 11.1 6.3 0.91 9.9 5.7 2.0 1 1 1 2 2 2 0 Pirin C-terminal cupin domain TERB2 PF15101.6 EKX51677.1 - 1.7 8.7 7.3 6 6.9 7.3 1.9 1 0 0 1 1 1 0 Telomere-associated protein TERB2 TPR_4 PF07721.14 EKX51677.1 - 4.7 8.1 12.4 3 8.7 0.4 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ubiquitin PF00240.23 EKX51678.1 - 3.1e-21 74.9 0.1 5.2e-21 74.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EKX51678.1 - 1.9e-14 53.2 0.0 3.4e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 EKX51678.1 - 1.1e-08 34.7 0.1 4e-08 33.0 0.1 2.0 1 0 0 1 1 1 1 UBA/TS-N domain Ubiquitin_2 PF14560.6 EKX51678.1 - 8.7e-08 32.5 0.1 3.2e-07 30.7 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain STI1 PF17830.1 EKX51678.1 - 1.8e-05 24.6 59.7 0.09 12.7 2.5 6.0 2 2 3 5 5 5 4 STI1 domain CUE PF02845.16 EKX51678.1 - 0.00024 20.7 0.1 0.0011 18.6 0.1 2.2 1 0 0 1 1 1 1 CUE domain DUF2407 PF10302.9 EKX51678.1 - 0.0019 18.7 0.0 0.0072 16.9 0.0 2.0 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain LPD22 PF18834.1 EKX51678.1 - 0.0032 17.6 5.4 4 7.7 0.8 3.8 2 1 1 3 3 3 2 Large polyvalent protein associated domain 22 Dynactin_p22 PF07426.11 EKX51678.1 - 0.0061 16.4 3.4 0.74 9.7 0.5 2.8 2 1 0 2 2 2 2 Dynactin subunit p22 Rad60-SLD_2 PF13881.6 EKX51678.1 - 0.014 15.5 0.0 0.032 14.3 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like HOIP-UBA PF16678.5 EKX51678.1 - 0.098 12.7 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 HOIP UBA domain pair Ubiquitin_5 PF18037.1 EKX51678.1 - 0.11 12.8 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_4 PF18036.1 EKX51678.1 - 0.15 12.2 0.2 3.3 7.8 0.1 2.4 1 1 1 2 2 2 0 Ubiquitin-like domain Speriolin_C PF15059.6 EKX51678.1 - 0.16 12.1 1.7 8.2 6.5 0.0 3.0 2 1 1 3 3 3 0 Speriolin C-terminus DUF1400 PF07176.11 EKX51678.1 - 0.18 12.1 2.5 5.6 7.3 0.3 3.2 2 1 1 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF1400) RPN13_C PF16550.5 EKX51678.1 - 0.24 11.6 14.2 0.13 12.4 2.3 2.6 2 0 0 2 2 2 0 UCH-binding domain ScsC_N PF18312.1 EKX51678.1 - 8.2 6.3 12.2 6 6.8 0.5 4.6 6 0 0 6 6 5 0 Copper resistance protein ScsC N-terminal domain 5-FTHF_cyc-lig PF01812.20 EKX51679.1 - 1.4e-36 126.1 0.0 2.5e-36 125.3 0.0 1.4 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Methyltransf_25 PF13649.6 EKX51680.1 - 2e-06 28.4 0.2 0.00034 21.2 0.2 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX51680.1 - 2.3e-06 27.5 1.0 0.0003 20.6 1.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX51680.1 - 0.00024 21.0 0.0 0.00036 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 EKX51680.1 - 0.0014 18.3 0.0 0.0057 16.3 0.0 1.7 1 1 1 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_12 PF08242.12 EKX51680.1 - 0.0073 17.0 0.1 0.17 12.6 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX51680.1 - 0.032 14.9 0.2 0.18 12.5 0.2 2.1 1 1 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 EKX51680.1 - 0.1 12.1 0.0 0.74 9.3 0.0 2.0 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Ion_trans PF00520.31 EKX51681.1 - 1.7e-14 53.7 13.8 2.4e-14 53.2 13.8 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 EKX51681.1 - 2.9e-11 43.3 0.1 1.7e-10 40.8 0.0 2.2 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EKX51681.1 - 7.5e-10 38.6 1.0 7.5e-10 38.6 1.0 1.8 2 0 0 2 2 2 1 Ion channel KIAA1430 PF13879.6 EKX51682.1 - 2.2e-27 95.8 4.3 5.5e-27 94.5 4.3 1.7 1 0 0 1 1 1 1 KIAA1430 homologue Ion_trans PF00520.31 EKX51683.1 - 2e-18 66.5 13.8 3.1e-18 65.9 13.8 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX51683.1 - 9.8e-13 47.9 1.3 9.8e-13 47.9 1.3 1.9 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 EKX51683.1 - 2.3e-11 43.6 0.1 1.5e-10 41.0 0.0 2.2 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain NIF PF03031.18 EKX51685.1 - 1.7e-47 161.1 0.6 1.9e-47 160.9 0.6 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Ank_2 PF12796.7 EKX51686.1 - 1.2e-20 73.9 3.9 3.1e-08 34.1 0.2 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EKX51686.1 - 8.5e-16 57.6 5.0 0.0015 18.9 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 EKX51686.1 - 5e-15 55.6 0.4 8e-05 23.1 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) BTB PF00651.31 EKX51686.1 - 6.1e-12 45.8 0.1 1.2e-11 44.8 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain Ank_5 PF13857.6 EKX51686.1 - 7.8e-12 45.2 1.8 2e-05 24.8 0.1 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX51686.1 - 5.4e-11 41.7 1.6 0.0052 17.2 0.0 6.4 6 0 0 6 6 6 2 Ankyrin repeat Dymeclin PF09742.9 EKX51686.1 - 0.0054 15.2 0.0 0.0089 14.5 0.0 1.3 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein PPR_2 PF13041.6 EKX51687.1 - 1.5e-34 118.0 0.0 8.8e-07 29.0 0.1 8.4 7 1 2 9 9 9 6 PPR repeat family PPR_3 PF13812.6 EKX51687.1 - 3.2e-31 107.2 0.0 2.5e-13 49.9 0.0 7.9 9 0 0 9 9 9 7 Pentatricopeptide repeat domain PPR_1 PF12854.7 EKX51687.1 - 9.3e-17 60.4 0.1 0.18 11.6 0.0 7.5 9 0 0 9 9 9 5 PPR repeat PPR_long PF17177.4 EKX51687.1 - 1.5e-14 53.9 2.0 4.2e-07 29.5 0.4 4.7 2 2 2 5 5 5 4 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EKX51687.1 - 1.1e-09 37.9 19.8 0.0027 17.9 0.0 10.1 9 2 1 10 10 10 3 PPR repeat RHSP PF07999.11 EKX51688.1 - 7.4e-05 21.7 1.8 0.00083 18.3 0.0 2.5 2 1 0 2 2 2 1 Retrotransposon hot spot protein IstB_IS21 PF01695.17 EKX51688.1 - 0.028 14.2 0.0 0.075 12.8 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein MeaB PF03308.16 EKX51688.1 - 0.083 11.9 2.1 0.23 10.4 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Mg_chelatase PF01078.21 EKX51688.1 - 0.098 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EKX51688.1 - 0.11 12.8 0.0 0.33 11.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase DUF2312 PF10073.9 EKX51688.1 - 0.57 9.9 6.4 0.3 10.8 3.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF4407 PF14362.6 EKX51688.1 - 0.69 9.2 9.0 1.1 8.5 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 EKX51688.1 - 0.87 9.9 2.6 2.5 8.4 2.6 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Seryl_tRNA_N PF02403.22 EKX51688.1 - 1.2 9.4 10.1 2.9 8.2 10.1 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Prominin PF05478.11 EKX51688.1 - 1.2 7.0 8.0 1.8 6.4 8.0 1.1 1 0 0 1 1 1 0 Prominin UPF0242 PF06785.11 EKX51688.1 - 2.3 8.3 18.3 6.3 6.8 18.3 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus COG2 PF06148.11 EKX51688.1 - 5.8 7.0 11.0 11 6.1 6.6 3.0 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4715 PF15835.5 EKX51688.1 - 5.8 7.0 12.5 8.8 6.4 10.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4715) Phycoerythr_ab PF02972.14 EKX51689.1 - 3.3e-28 97.2 0.0 5.4e-28 96.6 0.0 1.3 1 0 0 1 1 1 1 Phycoerythrin, alpha/beta chain Shugoshin_N PF07558.11 EKX51689.1 - 0.019 14.8 0.6 0.029 14.3 0.6 1.2 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region PsbQ PF05757.11 EKX51689.1 - 0.1 12.3 1.4 0.1 12.4 1.4 1.2 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Patatin PF01734.22 EKX51691.1 - 4.6e-06 27.0 0.9 2.5e-05 24.6 0.1 1.9 1 1 1 2 2 2 1 Patatin-like phospholipase Peptidase_M13_N PF05649.13 EKX51693.1 - 5.4e-33 115.2 0.0 6.8e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Frag1 PF10277.9 EKX51693.1 - 0.00045 19.8 0.6 0.00072 19.1 0.6 1.2 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family NusG_II PF07009.11 EKX51693.1 - 0.087 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 NusG domain II Peptidase_M13 PF01431.21 EKX51694.1 - 3.3e-49 167.3 0.0 3.9e-49 167.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M13 HA2 PF04408.23 EKX51695.1 - 1.2e-24 86.6 0.0 3.4e-24 85.2 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EKX51695.1 - 2e-18 66.5 0.0 4.1e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EKX51695.1 - 2.9e-14 53.3 0.0 7.4e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EKX51695.1 - 2.2e-09 37.3 0.0 4.1e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EKX51695.1 - 0.00014 22.1 0.2 0.00045 20.5 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EKX51695.1 - 0.0087 15.8 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EKX51695.1 - 0.014 15.4 0.0 0.038 14.0 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 EKX51695.1 - 0.058 12.4 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Flavi_DEAD PF07652.14 EKX51695.1 - 0.086 12.8 0.0 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_24 PF13479.6 EKX51695.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ephrin_rec_like PF07699.13 EKX51696.1 - 1.6e-15 56.6 63.5 4.8e-06 26.2 3.7 8.4 5 3 4 9 9 9 8 Putative ephrin-receptor like CIMR PF00878.18 EKX51696.1 - 2e-10 40.9 2.1 7.3e-05 22.9 0.2 3.1 3 0 0 3 3 3 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.10 EKX51696.1 - 2.2e-08 34.3 0.0 4.6e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Autophagy-related protein 27 PRKCSH_1 PF13015.6 EKX51696.1 - 2.1e-05 24.3 0.1 0.0002 21.1 0.0 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein WW PF00397.26 EKX51696.1 - 0.00011 22.2 0.7 0.00011 22.2 0.7 2.0 2 0 0 2 2 2 1 WW domain TNFR_c6 PF00020.18 EKX51696.1 - 0.35 11.3 45.9 2.7 8.5 2.2 9.5 6 3 1 8 8 8 0 TNFR/NGFR cysteine-rich region SBP_bac_3 PF00497.20 EKX51698.1 - 2.2e-20 73.1 0.0 4.3e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan-Glu_bd PF10613.9 EKX51698.1 - 2.5e-09 37.3 0.0 4.9e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Ligated ion channel L-glutamate- and glycine-binding site Lig_chan PF00060.26 EKX51698.1 - 0.0033 17.3 0.5 0.13 12.1 0.0 2.2 2 0 0 2 2 2 1 Ligand-gated ion channel ISG65-75 PF11727.8 EKX51698.1 - 0.059 12.6 0.0 0.095 11.9 0.0 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein WD40 PF00400.32 EKX51699.1 - 2.9e-07 31.1 2.4 0.37 11.7 0.1 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat BBS2_Mid PF14783.6 EKX51699.1 - 0.096 12.7 0.0 0.4 10.8 0.0 2.0 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region SET PF00856.28 EKX51700.1 - 2.6e-15 57.2 0.0 3.1e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 SET domain RRM_1 PF00076.22 EKX51702.1 - 4.4e-12 45.6 0.1 6.3e-09 35.5 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PA14 PF07691.12 EKX51703.1 - 5e-20 71.8 0.1 3.5e-16 59.3 0.0 2.9 2 0 0 2 2 2 2 PA14 domain Filamin PF00630.19 EKX51703.1 - 5.7e-11 43.2 2.0 0.0029 18.4 0.0 6.9 7 1 0 7 7 7 3 Filamin/ABP280 repeat YHYH PF14240.6 EKX51703.1 - 0.0047 16.9 7.4 0.26 11.2 0.0 3.5 2 1 2 4 4 4 2 YHYH protein GLEYA PF10528.9 EKX51703.1 - 0.72 10.3 3.9 0.54 10.7 0.1 2.9 3 0 0 3 3 3 0 GLEYA domain DUF4215 PF13948.6 EKX51708.1 - 5e-15 55.7 17.5 2.6e-07 31.0 7.9 3.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4215) PA14 PF07691.12 EKX51708.1 - 0.0019 18.0 0.0 0.0044 16.8 0.0 1.5 1 0 0 1 1 1 1 PA14 domain ZZ PF00569.17 EKX51708.1 - 1.5 8.7 4.8 3.5 7.5 0.1 2.6 2 0 0 2 2 2 0 Zinc finger, ZZ type Ribosomal_L7Ae PF01248.26 EKX51709.1 - 6.4e-15 54.7 0.0 1.4e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family EF-hand_1 PF00036.32 EKX51711.1 - 2.9e-11 42.1 2.8 7.1e-05 22.1 0.4 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX51711.1 - 3.4e-10 39.0 4.0 0.00026 20.7 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EKX51711.1 - 1e-09 38.7 3.0 1.1e-09 38.6 3.0 1.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX51711.1 - 2.9e-08 32.8 3.0 0.00068 19.0 0.2 2.1 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX51711.1 - 3.3e-08 33.2 2.0 3.2e-05 23.7 0.2 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_10 PF14788.6 EKX51711.1 - 0.023 14.5 0.2 0.045 13.6 0.1 1.5 1 1 1 2 2 2 0 EF hand EF-hand_9 PF14658.6 EKX51711.1 - 0.11 12.9 0.1 0.12 12.7 0.1 1.0 1 0 0 1 1 1 0 EF-hand domain EF-hand_4 PF12763.7 EKX51711.1 - 0.19 11.7 1.2 10 6.1 0.2 2.0 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Arg_decarbox_C PF17944.1 EKX51712.1 - 0.084 13.4 0.1 8 7.1 0.0 3.3 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension Ank PF00023.30 EKX51714.1 - 6.1e-16 58.1 0.3 0.0057 17.0 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 EKX51714.1 - 2.4e-15 56.9 0.7 6.7e-12 45.8 0.2 2.5 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX51714.1 - 3.7e-12 45.3 0.2 0.016 15.7 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EKX51714.1 - 5.6e-10 39.5 0.5 5e-06 27.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX51714.1 - 3.2e-07 30.5 0.2 3.3e-05 24.1 0.0 3.8 3 1 1 4 4 4 1 Ankyrin repeats (many copies) TPR_18 PF13512.6 EKX51714.1 - 0.12 12.4 0.6 12 6.0 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat YfdX PF10938.8 EKX51714.1 - 1.7 8.6 7.4 6.8 6.6 0.9 3.1 3 0 0 3 3 3 0 YfdX protein TPR_16 PF13432.6 EKX51714.1 - 2.7 8.7 17.7 2.1 9.0 5.8 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX51714.1 - 10 6.7 5.9 45 4.6 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat GTA_holin_3TM PF11351.8 EKX51715.1 - 0.13 12.8 0.1 0.27 11.8 0.1 1.6 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release PalH PF08733.10 EKX51715.1 - 0.19 10.7 2.7 0.18 10.8 0.9 1.8 2 0 0 2 2 2 0 PalH/RIM21 TMEM100 PF16311.5 EKX51715.1 - 0.21 11.2 1.7 6.3 6.4 0.0 2.5 2 0 0 2 2 2 0 Transmembrane protein 100 Ank_5 PF13857.6 EKX51716.1 - 2.8e-15 56.2 1.6 1.1e-09 38.4 1.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX51716.1 - 3.2e-13 50.1 0.2 4.5e-13 49.6 0.2 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX51716.1 - 2e-12 47.3 3.2 1.8e-09 37.9 0.4 1.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX51716.1 - 1.8e-10 40.1 0.2 0.00069 19.9 0.4 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EKX51716.1 - 3.7e-09 36.6 3.4 7.4e-05 23.0 1.1 2.6 3 1 0 3 3 3 2 Ankyrin repeat SET PF00856.28 EKX51718.1 - 1.1 9.6 9.0 0.57 10.6 0.3 3.6 3 2 0 3 3 3 0 SET domain Sds3 PF08598.11 EKX51719.1 - 0.061 13.3 0.0 0.17 11.8 0.0 1.5 1 1 0 1 1 1 0 Sds3-like Cnd1 PF12717.7 EKX51720.1 - 2.1e-26 92.9 9.8 8e-21 74.8 0.1 4.1 2 1 1 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EKX51720.1 - 0.0016 18.5 13.1 0.08 13.2 0.4 6.1 7 0 0 7 7 7 1 HEAT repeat RTP1_C1 PF10363.9 EKX51720.1 - 0.0041 17.3 7.1 0.13 12.5 1.2 4.3 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 EKX51720.1 - 0.68 10.4 13.4 2.3 8.7 0.1 5.6 5 2 2 7 7 7 0 HEAT repeats Cohesin_HEAT PF12765.7 EKX51720.1 - 1 9.7 9.3 1.3 9.4 0.6 4.0 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion FANCI_S2 PF14676.6 EKX51720.1 - 5.1 7.4 11.2 0.72 10.1 0.6 3.2 3 0 0 3 3 3 0 FANCI solenoid 2 Thioredoxin PF00085.20 EKX51721.1 - 5.9e-47 157.9 0.0 5.6e-25 87.3 0.0 2.4 2 1 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 EKX51721.1 - 3.6e-13 49.9 0.0 4.9e-05 23.7 0.0 2.7 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EKX51721.1 - 3.7e-13 49.5 0.0 5.1e-06 26.1 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family ERp29 PF07749.12 EKX51721.1 - 2e-12 47.9 1.1 7e-12 46.1 0.0 2.4 3 1 0 3 3 3 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_7 PF13899.6 EKX51721.1 - 2.9e-07 30.6 0.1 0.022 14.9 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 EKX51721.1 - 5.4e-07 29.6 0.0 0.0054 16.6 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_8 PF13905.6 EKX51721.1 - 4.7e-06 26.8 0.9 0.28 11.5 0.1 3.8 3 2 0 3 3 3 2 Thioredoxin-like Redoxin PF08534.10 EKX51721.1 - 1e-05 25.3 0.0 0.06 13.1 0.0 2.4 2 0 0 2 2 2 2 Redoxin ERp29_N PF07912.13 EKX51721.1 - 0.00051 20.2 0.1 0.32 11.1 0.0 2.6 2 2 0 2 2 2 2 ERp29, N-terminal domain Thioredoxin_9 PF14595.6 EKX51721.1 - 0.031 14.1 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin MqsA_antitoxin PF15731.5 EKX51721.1 - 0.063 13.4 0.1 1.6 8.8 0.0 2.9 2 1 2 4 4 4 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA TraF PF13728.6 EKX51721.1 - 0.093 12.5 0.0 14 5.4 0.0 2.6 2 1 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 EKX51721.1 - 0.11 12.6 0.2 15 5.7 0.0 3.2 3 0 0 3 3 3 0 Thioredoxin PAPS_reduct PF01507.19 EKX51724.1 - 3.5e-21 76.0 0.0 2.6e-12 47.1 0.0 2.2 1 1 0 2 2 2 2 Phosphoadenosine phosphosulfate reductase family MoCF_biosynth PF00994.24 EKX51724.1 - 2.2e-12 46.9 0.3 3.2e-12 46.3 0.3 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain ATP_bind_3 PF01171.20 EKX51724.1 - 0.21 11.3 0.0 0.42 10.4 0.0 1.6 2 0 0 2 2 2 0 PP-loop family RRM_1 PF00076.22 EKX51725.1 - 2.9e-14 52.6 0.0 3.8e-07 29.8 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BING4CT PF08149.11 EKX51725.1 - 0.023 14.5 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 BING4CT (NUC141) domain RRM_occluded PF16842.5 EKX51725.1 - 0.044 13.7 0.0 6.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif ANAPC4 PF12896.7 EKX51726.1 - 2.6e-37 128.3 8.5 4.8e-37 127.4 8.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 EKX51726.1 - 6.8e-25 87.2 1.1 2.6e-24 85.3 0.5 2.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EKX51726.1 - 8.6e-07 29.6 0.1 8.6e-07 29.6 0.1 4.0 5 0 0 5 5 5 1 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EKX51726.1 - 0.0016 17.5 0.7 0.013 14.5 0.0 2.3 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DPPIV_N PF00930.21 EKX51726.1 - 0.1 11.4 0.2 1.2 7.8 0.2 2.1 1 1 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Med2 PF11214.8 EKX51726.1 - 0.32 11.2 3.4 0.64 10.2 0.9 2.5 2 0 0 2 2 2 0 Mediator complex subunit 2 SnoaL_2 PF12680.7 EKX51727.1 - 1.5e-09 38.4 0.0 1.7e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EKX51727.1 - 5.3e-05 23.0 0.0 6.6e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_3 PF13474.6 EKX51727.1 - 0.096 12.9 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain Rubis-subs-bind PF09273.11 EKX51728.1 - 2.7e-08 34.5 0.1 8.1e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.28 EKX51728.1 - 0.0021 18.4 0.0 0.0044 17.4 0.0 1.6 1 1 0 1 1 1 1 SET domain Pkinase PF00069.25 EKX51729.1 - 3.7e-71 239.6 0.0 4.5e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX51729.1 - 1.2e-35 123.0 0.1 2.2e-34 118.9 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX51729.1 - 1e-05 25.0 0.1 0.00011 21.7 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EKX51729.1 - 2.5e-05 23.4 1.9 4.5e-05 22.6 1.9 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EKX51729.1 - 0.0058 16.0 0.5 0.0096 15.3 0.5 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX51729.1 - 0.0062 16.5 0.1 0.39 10.6 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EKX51729.1 - 0.054 13.1 1.4 3.7 7.1 0.1 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EKX51729.1 - 0.1 11.4 0.0 0.31 9.8 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase FeoB_N PF02421.18 EKX51729.1 - 0.12 11.9 0.5 0.84 9.2 0.4 1.9 1 1 1 2 2 2 0 Ferrous iron transport protein B IPK PF03770.16 EKX51730.1 - 8.7e-26 91.0 0.0 1.4e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase HEPN_AbiU2 PF18734.1 EKX51731.1 - 0.0029 17.2 0.3 0.0045 16.5 0.3 1.5 1 0 0 1 1 1 1 AbiU2 Presenilin PF01080.17 EKX51731.1 - 3.3 6.4 4.6 4.9 5.8 4.6 1.2 1 0 0 1 1 1 0 Presenilin TonB_N PF16031.5 EKX51732.1 - 0.85 10.1 12.2 1.6 9.2 12.2 1.4 1 0 0 1 1 1 0 TonB polyproline region UEV PF05743.13 EKX51733.1 - 3.2e-26 91.6 0.0 6.3e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 UEV domain U-box PF04564.15 EKX51733.1 - 4.3e-20 71.7 0.1 1.3e-19 70.1 0.1 1.8 1 0 0 1 1 1 1 U-box domain UQ_con PF00179.26 EKX51733.1 - 4.9e-05 23.0 0.2 8.3e-05 22.3 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-Nse PF11789.8 EKX51733.1 - 7.6e-05 22.5 0.1 0.00033 20.4 0.0 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Histone_HNS PF00816.21 EKX51733.1 - 0.1 13.4 0.2 3 8.7 0.1 2.4 2 0 0 2 2 2 0 H-NS histone family zf-NOSIP PF15906.5 EKX51733.1 - 0.14 12.3 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein TF_AP-2 PF03299.14 EKX51733.1 - 0.23 11.4 1.3 0.38 10.7 0.4 1.8 2 0 0 2 2 2 0 Transcription factor AP-2 TIG PF01833.24 EKX51734.1 - 7.2e-21 74.1 81.3 0.00067 19.7 0.1 16.6 18 0 0 18 18 18 11 IPT/TIG domain DUF4394 PF14339.6 EKX51734.1 - 4.5e-08 32.7 12.5 0.035 13.5 0.1 5.3 6 0 0 6 6 6 3 Domain of unknown function (DUF4394) Nuc_deoxyri_tr3 PF11071.8 EKX51734.1 - 0.0022 18.1 0.0 29 4.7 0.0 3.3 3 0 0 3 3 3 3 Nucleoside 2-deoxyribosyltransferase YtoQ RseA_C PF03873.13 EKX51734.1 - 1.2 9.4 8.8 34 4.8 0.1 3.9 3 0 0 3 3 3 0 Anti sigma-E protein RseA, C-terminal domain Innate_immun PF12782.7 EKX51734.1 - 2.5 7.5 3.9 96 2.3 0.1 3.1 3 0 0 3 3 3 0 Invertebrate innate immunity transcript family Bac_rhodopsin PF01036.18 EKX51735.1 - 8.7e-30 104.0 18.8 1.1e-29 103.7 18.8 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein TMEM132D_C PF15706.5 EKX51735.1 - 0.042 13.6 3.1 1.6 8.6 0.1 2.3 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term PDR_assoc PF08370.11 EKX51735.1 - 0.088 12.6 7.3 1.8 8.4 1.3 3.3 3 0 0 3 3 3 0 Plant PDR ABC transporter associated JmjC PF02373.22 EKX51736.1 - 1.7e-41 141.2 0.2 2.8e-41 140.5 0.2 1.3 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 EKX51736.1 - 4.4e-14 52.2 0.1 8.6e-14 51.2 0.1 1.5 1 0 0 1 1 1 1 jmjN domain PARG_cat PF05028.14 EKX51737.1 - 3.4e-62 210.7 0.0 5.7e-62 210.0 0.0 1.3 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) TPR_2 PF07719.17 EKX51738.1 - 2.5e-23 80.2 29.3 0.0052 16.8 0.1 13.2 13 0 0 13 13 13 7 Tetratricopeptide repeat TPR_16 PF13432.6 EKX51738.1 - 1.4e-19 70.5 56.0 0.0012 19.4 0.5 11.3 11 1 0 11 11 10 7 Tetratricopeptide repeat TPR_12 PF13424.6 EKX51738.1 - 2e-19 69.7 46.0 2.4e-06 27.7 0.2 11.7 12 1 3 15 15 13 7 Tetratricopeptide repeat TPR_1 PF00515.28 EKX51738.1 - 3.3e-16 58.3 13.3 0.0048 16.7 0.1 10.4 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX51738.1 - 2.4e-15 55.4 8.0 0.11 12.8 0.0 9.2 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 EKX51738.1 - 6.8e-11 42.5 52.8 0.0071 16.8 3.0 12.2 14 0 0 14 14 11 4 Tetratricopeptide repeat TPR_11 PF13414.6 EKX51738.1 - 7.1e-11 41.6 1.5 0.76 9.5 0.1 8.3 8 0 0 8 8 8 1 TPR repeat TPR_17 PF13431.6 EKX51738.1 - 2.1e-10 40.2 12.3 0.021 15.2 0.1 10.8 12 0 0 12 12 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX51738.1 - 5.6e-09 35.4 22.0 0.024 14.6 0.1 10.0 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX51738.1 - 1.5e-08 34.7 76.2 0.004 17.8 1.6 16.7 11 5 10 21 21 18 4 Tetratricopeptide repeat TPR_10 PF13374.6 EKX51738.1 - 4.2e-06 26.4 26.8 0.0045 16.8 0.2 8.9 10 0 0 10 10 9 2 Tetratricopeptide repeat Wzy_C_2 PF11846.8 EKX51738.1 - 0.0019 18.2 1.8 0.016 15.1 0.0 3.0 2 1 1 3 3 3 1 Virulence factor membrane-bound polymerase, C-terminal Tcf25 PF04910.14 EKX51738.1 - 0.004 16.3 0.1 0.034 13.2 0.0 2.6 2 0 0 2 2 2 1 Transcriptional repressor TCF25 Fis1_TPR_C PF14853.6 EKX51738.1 - 0.0063 16.6 15.4 0.02 15.0 0.1 6.4 7 0 0 7 7 7 1 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 EKX51738.1 - 0.026 15.1 18.8 56 4.7 0.1 9.2 9 0 0 9 9 8 0 Tetratricopeptide repeat SHE3 PF17078.5 EKX51738.1 - 0.081 12.6 7.4 0.084 12.6 5.1 2.2 2 0 0 2 2 1 0 SWI5-dependent HO expression protein 3 MscS_TM PF12794.7 EKX51738.1 - 0.082 11.7 1.2 0.22 10.4 1.2 1.6 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 TPR_9 PF13371.6 EKX51738.1 - 0.11 12.6 43.9 0.17 12.1 2.2 8.3 6 2 2 8 8 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX51738.1 - 0.14 12.4 12.8 4.1 7.7 0.2 6.4 6 1 0 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4810 PF16068.5 EKX51738.1 - 0.26 11.9 5.7 1.8 9.1 0.0 3.7 2 1 1 3 3 2 0 Domain of unknown function (DUF4810) TPR_20 PF14561.6 EKX51738.1 - 2 8.8 10.3 2.7 8.4 0.1 5.0 5 1 1 6 6 5 0 Tetratricopeptide repeat MerR-DNA-bind PF09278.11 EKX51738.1 - 2.7 8.6 14.9 0.14 12.7 0.7 4.4 4 0 0 4 4 3 0 MerR, DNA binding MIT PF04212.18 EKX51738.1 - 3.8 7.7 15.7 39 4.4 0.0 7.0 8 0 0 8 8 7 0 MIT (microtubule interacting and transport) domain Alpha_kinase PF02816.18 EKX51742.1 - 1.4e-52 178.5 1.7 1.5e-52 178.4 0.5 1.7 2 0 0 2 2 2 1 Alpha-kinase family DUF1388 PF07142.12 EKX51742.1 - 9.5e-06 25.5 16.0 3.6e-05 23.6 5.1 3.2 2 1 2 4 4 4 2 Repeat of unknown function (DUF1388) GAIN_A PF18619.1 EKX51742.1 - 0.8 10.0 7.9 15 5.9 2.8 3.1 2 0 0 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A SlyX PF04102.12 EKX51742.1 - 2.9 8.6 9.6 11 6.7 0.1 3.1 3 0 0 3 3 3 0 SlyX FHA PF00498.26 EKX51743.1 - 1.2e-10 41.5 0.4 2.3e-10 40.7 0.4 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EKX51743.1 - 1.7e-09 37.9 0.0 3.8e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 EKX51743.1 - 0.029 14.6 0.0 0.18 12.1 0.0 2.1 2 0 0 2 2 2 0 FHA domain AKAP7_RIRII_bdg PF10470.9 EKX51744.1 - 5.7e-06 26.3 2.5 18 5.5 0.0 5.2 5 0 0 5 5 5 4 PKA-RI-RII subunit binding domain of A-kinase anchor protein TetR_C_31 PF17940.1 EKX51744.1 - 0.018 15.2 8.1 13 6.0 0.1 4.4 4 1 1 5 5 5 0 Tetracyclin repressor-like, C-terminal domain Desulfoferrod_N PF06397.12 EKX51744.1 - 1.2 8.8 12.6 20 4.9 0.4 4.2 4 0 0 4 4 4 0 Desulfoferrodoxin, N-terminal domain FtsX PF02687.21 EKX51745.1 - 2.1e-17 63.3 16.2 8.5e-11 42.2 6.0 6.3 7 1 0 7 7 7 3 FtsX-like permease family Cadherin_C_2 PF16492.5 EKX51745.1 - 4 8.3 9.1 23 5.8 0.3 3.0 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal IMS PF00817.20 EKX51746.1 - 3.7e-40 137.4 0.1 5.7e-40 136.8 0.1 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.8 EKX51746.1 - 3.7e-05 23.8 0.0 0.00011 22.3 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif IMS_C PF11799.8 EKX51746.1 - 0.00014 22.5 0.0 0.0003 21.5 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain SicP-binding PF09119.10 EKX51746.1 - 0.14 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 SicP binding IlvC PF01450.19 EKX51747.1 - 0.022 15.1 0.6 0.038 14.3 0.6 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain TPR_11 PF13414.6 EKX51748.1 - 2.1e-30 104.1 9.4 3.4e-11 42.6 0.1 5.6 2 1 3 5 5 5 4 TPR repeat TPR_1 PF00515.28 EKX51748.1 - 2.6e-30 102.9 22.1 3.1e-07 29.9 0.1 7.3 6 2 1 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 EKX51748.1 - 2.1e-25 86.7 20.1 3.4e-07 29.9 0.1 7.1 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 EKX51748.1 - 1.6e-24 83.9 18.7 1.8e-06 27.6 0.1 7.3 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 EKX51748.1 - 2e-19 70.0 4.5 2.1e-08 34.6 0.1 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX51748.1 - 9.3e-19 66.0 6.5 0.00013 21.7 0.0 6.4 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX51748.1 - 4.1e-17 62.2 15.3 1.5e-05 25.2 0.2 6.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX51748.1 - 1e-16 60.2 4.7 0.00011 22.7 0.0 6.6 1 1 6 7 7 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 EKX51748.1 - 6.7e-16 57.5 13.7 3.6e-06 27.0 0.1 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 EKX51748.1 - 2e-15 57.0 14.8 1.3e-06 28.8 1.1 4.5 2 2 2 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX51748.1 - 7.6e-11 41.5 14.4 2.2e-06 27.3 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX51748.1 - 1.2e-07 31.7 0.9 0.024 14.8 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX51748.1 - 6.7e-07 29.4 9.1 0.0075 16.5 0.5 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EKX51748.1 - 8.6e-06 26.1 20.9 0.014 16.0 0.0 6.8 8 1 1 9 9 6 2 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 EKX51748.1 - 3.1e-05 23.6 3.5 0.0055 16.2 0.2 2.6 1 1 1 2 2 2 2 Est1 DNA/RNA binding domain YqhG PF11079.8 EKX51748.1 - 0.00067 18.7 1.5 0.0078 15.2 0.4 2.4 2 1 0 2 2 2 1 Bacterial protein YqhG of unknown function Glyco_hyd_65N_2 PF14498.6 EKX51748.1 - 0.00069 19.5 0.9 0.0065 16.4 0.2 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, N-terminal domain Coatomer_E PF04733.14 EKX51748.1 - 0.0011 18.4 2.4 0.0092 15.4 0.4 2.5 1 1 1 2 2 2 1 Coatomer epsilon subunit TPR_20 PF14561.6 EKX51748.1 - 0.003 17.8 8.6 0.38 11.1 0.4 3.4 3 1 0 3 3 2 2 Tetratricopeptide repeat BTAD PF03704.17 EKX51748.1 - 0.013 15.9 9.3 1.6 9.2 0.8 3.5 1 1 2 3 3 3 0 Bacterial transcriptional activator domain Vps53_N PF04100.12 EKX51748.1 - 0.037 13.0 0.4 0.037 13.0 0.4 2.2 2 0 0 2 2 2 0 Vps53-like, N-terminal TPR_4 PF07721.14 EKX51748.1 - 0.054 14.1 0.0 47 5.0 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3130 PF11328.8 EKX51748.1 - 0.07 13.4 0.0 0.36 11.1 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3130 LXG PF04740.12 EKX51748.1 - 0.092 12.4 6.4 0.46 10.2 0.1 2.9 3 0 0 3 3 3 0 LXG domain of WXG superfamily NARP1 PF12569.8 EKX51748.1 - 0.094 11.6 0.0 0.094 11.6 0.0 3.4 2 1 1 4 4 4 0 NMDA receptor-regulated protein 1 ING PF12998.7 EKX51748.1 - 0.11 13.1 4.6 1.2 9.8 0.7 2.5 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Fis1_TPR_C PF14853.6 EKX51748.1 - 0.12 12.5 6.4 8.1 6.6 0.1 4.4 3 2 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF4570 PF15134.6 EKX51748.1 - 0.14 12.2 0.2 0.14 12.2 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4570) DUF627 PF04781.12 EKX51748.1 - 0.15 12.1 1.8 0.4 10.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF627) DUF4795 PF16043.5 EKX51748.1 - 0.33 10.5 10.1 4.7 6.8 1.1 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4795) MIT PF04212.18 EKX51748.1 - 0.64 10.1 11.7 17 5.6 0.0 5.1 4 2 1 5 5 4 0 MIT (microtubule interacting and transport) domain DUF5344 PF17279.2 EKX51748.1 - 3.2 8.4 15.9 0.24 12.0 2.3 4.1 4 2 1 5 5 3 0 Family of unknown function (DUF5344) Prefoldin_2 PF01920.20 EKX51748.1 - 8.5 6.4 18.3 6.3 6.8 1.3 4.7 4 2 1 5 5 5 0 Prefoldin subunit Bac_rhodopsin PF01036.18 EKX51749.1 - 9.7e-47 159.4 22.2 1.2e-46 159.0 22.2 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein OST3_OST6 PF04756.13 EKX51749.1 - 0.044 13.1 0.6 0.044 13.1 0.6 1.7 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family DUF2721 PF11026.8 EKX51749.1 - 4.3 7.2 7.8 1.7 8.5 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF21 PF01595.20 EKX51749.1 - 9.2 5.9 11.5 0.27 10.9 4.8 1.8 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain RGP PF03214.13 EKX51750.1 - 4e-12 45.9 0.0 6e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Reversibly glycosylated polypeptide Cytochrom_B561 PF03188.16 EKX51751.1 - 1.6e-17 63.9 9.9 3.3e-16 59.7 6.6 2.6 2 1 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 EKX51751.1 - 1.9 8.7 8.2 10 6.3 8.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) Ni_hydr_CYTB PF01292.20 EKX51751.1 - 4.3 6.9 10.9 4.7 6.8 8.3 2.3 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 Cytochrom_B561 PF03188.16 EKX51752.1 - 1.1e-18 67.7 6.6 2.3e-16 60.2 6.6 2.6 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 EKX51752.1 - 1.6 8.9 8.5 9.3 6.4 8.5 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) DUF4293 PF14126.6 EKX51752.1 - 3 8.1 5.1 2.5 8.3 0.2 2.9 2 2 2 4 4 4 0 Domain of unknown function (DUF4293) Ni_hydr_CYTB PF01292.20 EKX51752.1 - 5.7 6.5 11.8 3.7 7.1 0.2 2.4 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 zf-C2HE PF16278.5 EKX51753.1 - 3.6e-11 43.3 0.5 9.5e-11 42.0 0.0 1.9 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger BRCT PF00533.26 EKX51753.1 - 0.01 16.2 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EKX51753.1 - 0.085 13.3 0.0 0.3 11.5 0.0 1.9 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain Hormone_1 PF00103.20 EKX51755.1 - 0.09 12.5 1.2 0.24 11.1 1.2 1.6 1 0 0 1 1 1 0 Somatotropin hormone family Vps39_1 PF10366.9 EKX51755.1 - 0.11 12.8 0.1 0.3 11.4 0.1 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Cnn_1N PF07989.11 EKX51755.1 - 0.51 10.5 5.0 15 5.8 0.1 2.8 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Cep57_MT_bd PF06657.13 EKX51755.1 - 4.9 7.7 9.8 13 6.4 5.3 3.4 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Wbp11 PF09429.10 EKX51755.1 - 6.8 7.2 8.2 3 8.3 0.0 3.6 3 0 0 3 3 3 0 WW domain binding protein 11 DEAD_2 PF06733.15 EKX51756.1 - 0.13 11.9 1.7 0.42 10.2 0.1 2.1 2 0 0 2 2 2 0 DEAD_2 CAF1 PF04857.20 EKX51759.1 - 6.6e-62 209.5 0.1 8.1e-62 209.2 0.1 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease Lipase_GDSL_2 PF13472.6 EKX51761.1 - 0.018 15.4 0.0 0.099 13.0 0.0 2.0 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family WH1 PF00568.23 EKX51761.1 - 0.13 12.2 0.1 3.7 7.5 0.0 2.2 2 0 0 2 2 2 0 WH1 domain XPA_C PF05181.12 EKX51763.1 - 1.4e-05 25.0 0.3 2.8e-05 24.0 0.3 1.5 1 0 0 1 1 1 1 XPA protein C-terminus Trypan_PARP PF05887.11 EKX51763.1 - 0.0015 18.5 5.8 0.003 17.6 5.8 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF4834 PF16118.5 EKX51763.1 - 0.0066 17.4 8.4 0.0066 17.4 8.4 2.2 2 1 0 2 2 1 1 Domain of unknown function (DUF4834) SpoIIP PF07454.11 EKX51763.1 - 0.007 15.9 4.3 0.012 15.1 4.3 1.4 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) SID-1_RNA_chan PF13965.6 EKX51763.1 - 0.0094 14.4 0.0 0.015 13.8 0.0 1.2 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Lin-8 PF03353.15 EKX51763.1 - 0.022 14.3 8.2 0.024 14.2 4.7 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist NPR3 PF03666.13 EKX51763.1 - 0.053 12.3 3.9 0.091 11.5 3.9 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 T2SSF PF00482.23 EKX51763.1 - 0.067 13.2 3.7 1.1 9.2 2.3 2.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Plasmodium_Vir PF05795.11 EKX51763.1 - 0.068 12.6 1.2 0.12 11.7 1.2 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DNA_pol_phi PF04931.13 EKX51763.1 - 0.082 11.0 7.7 0.12 10.5 7.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF2722 PF10846.8 EKX51763.1 - 0.12 11.3 10.5 0.19 10.7 10.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF2052 PF09747.9 EKX51763.1 - 0.21 11.7 21.1 0.016 15.4 15.1 1.9 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) TERB2 PF15101.6 EKX51763.1 - 0.28 11.2 9.3 0.73 9.9 9.3 1.6 1 0 0 1 1 1 0 Telomere-associated protein TERB2 EIIBC-GUT_N PF03612.14 EKX51763.1 - 0.34 10.6 5.4 0.86 9.3 5.4 1.6 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus XAP5 PF04921.14 EKX51763.1 - 0.39 10.5 7.8 0.79 9.5 7.8 1.4 1 0 0 1 1 1 0 XAP5, circadian clock regulator Ycf1 PF05758.12 EKX51763.1 - 0.51 8.1 2.8 1 7.2 2.8 1.4 1 0 0 1 1 1 0 Ycf1 RNA_pol_Rpc4 PF05132.14 EKX51763.1 - 0.61 10.5 7.9 0.12 12.8 3.5 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 XRN_M PF17846.1 EKX51763.1 - 0.62 9.0 4.2 0.99 8.3 4.2 1.3 1 0 0 1 1 1 0 Xrn1 helical domain DUF4628 PF15429.6 EKX51763.1 - 0.91 9.1 8.8 0.36 10.5 4.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4628) SLC12 PF03522.15 EKX51763.1 - 1.1 8.3 5.8 1.8 7.5 5.8 1.3 1 0 0 1 1 1 0 Solute carrier family 12 PIP5K PF01504.18 EKX51763.1 - 1.2 8.2 4.0 2.4 7.3 4.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase AAA_11 PF13086.6 EKX51763.1 - 1.3 8.8 9.0 0.12 12.2 4.4 1.6 2 0 0 2 2 2 0 AAA domain DUF913 PF06025.12 EKX51763.1 - 1.5 7.7 6.6 0.24 10.4 2.7 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) MDM10 PF12519.8 EKX51763.1 - 1.8 7.4 6.8 2.6 6.8 6.8 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Myc_N PF01056.18 EKX51763.1 - 2 8.3 9.6 1 9.2 7.3 1.6 2 0 0 2 2 2 0 Myc amino-terminal region Presenilin PF01080.17 EKX51763.1 - 2.5 6.7 16.5 0.019 13.7 5.0 2.2 2 0 0 2 2 2 0 Presenilin mono-CXXC PF15626.6 EKX51763.1 - 3.5 8.0 8.3 0.62 10.5 2.9 2.4 3 0 0 3 3 2 0 single CXXC unit Usp PF00582.26 EKX51763.1 - 4.7 7.7 6.3 0.55 10.7 1.6 2.0 2 0 0 2 2 1 0 Universal stress protein family CTU2 PF10288.9 EKX51763.1 - 5.2 7.3 8.8 1.6 9.0 5.0 2.1 2 0 0 2 2 1 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF4064 PF13273.6 EKX51763.1 - 8.7 6.7 7.8 8.2 6.8 2.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Hid1 PF12722.7 EKX51763.1 - 9.6 4.2 6.9 18 3.3 6.9 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein OTU PF02338.19 EKX51764.1 - 7e-27 94.4 0.3 1.2e-26 93.7 0.3 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EKX51764.1 - 4.6e-07 29.5 0.0 0.00012 21.6 0.0 2.0 2 0 0 2 2 2 2 Peptidase C65 Otubain Phage_int_SAM_1 PF02899.17 EKX51764.1 - 0.0052 17.0 0.1 0.012 15.9 0.1 1.5 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain GTP_EFTU PF00009.27 EKX51765.1 - 9e-67 224.4 0.0 1.6e-66 223.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EKX51765.1 - 3.1e-43 146.4 0.1 6.4e-43 145.4 0.1 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 EKX51765.1 - 4e-33 113.3 0.1 7.3e-33 112.5 0.1 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EKX51765.1 - 1.7e-28 98.5 0.0 4.8e-28 97.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EKX51765.1 - 3.4e-15 56.2 0.7 7.8e-15 55.0 0.4 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EKX51765.1 - 4.9e-07 29.6 0.0 1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 EKX51765.1 - 0.0023 18.0 0.1 0.011 15.9 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 EKX51765.1 - 0.044 13.1 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 AIG1 family ANP PF00212.18 EKX51765.1 - 0.1 12.8 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Atrial natriuretic peptide PAH PF02671.21 EKX51766.1 - 9.2e-14 51.3 8.3 4.4e-08 33.1 2.1 2.4 2 0 0 2 2 2 2 Paired amphipathic helix repeat DUF1722 PF08349.11 EKX51766.1 - 0.00013 22.2 3.4 0.00038 20.7 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1722) CCM2_C PF16545.5 EKX51766.1 - 0.015 15.8 0.3 0.041 14.4 0.3 1.9 1 1 0 1 1 1 0 Cerebral cavernous malformation protein, harmonin-homology GrpE PF01025.19 EKX51766.1 - 0.12 12.0 2.8 0.11 12.1 0.3 2.1 2 0 0 2 2 2 0 GrpE Thioredoxin PF00085.20 EKX51767.1 - 4.5e-22 78.0 0.2 6.7e-22 77.4 0.2 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EKX51767.1 - 0.00047 20.4 0.1 0.0017 18.7 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EKX51767.1 - 0.00052 20.4 0.7 0.0043 17.5 0.7 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EKX51767.1 - 0.00065 19.1 0.0 0.00099 18.5 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EKX51767.1 - 0.0014 18.7 0.1 0.0026 17.9 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 EKX51767.1 - 0.0036 17.5 0.1 0.0068 16.6 0.1 1.5 1 0 0 1 1 1 1 Glutaredoxin AhpC-TSA PF00578.21 EKX51767.1 - 0.0069 16.3 0.0 0.0094 15.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EKX51767.1 - 0.036 13.8 0.2 0.062 13.0 0.2 1.5 1 1 0 1 1 1 0 Redoxin Thioredoxin_3 PF13192.6 EKX51767.1 - 0.045 13.8 0.0 0.075 13.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_9 PF14595.6 EKX51767.1 - 0.094 12.5 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin His_Phos_1 PF00300.22 EKX51768.1 - 1.3e-08 34.8 0.5 2.2e-08 34.0 0.5 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RWP-RK PF02042.15 EKX51769.1 - 1.3e-14 53.9 0.5 2.6e-14 52.9 0.5 1.5 1 0 0 1 1 1 1 RWP-RK domain PAP2 PF01569.21 EKX51770.1 - 1.2e-07 31.6 11.7 2.6e-07 30.5 8.7 2.5 2 1 0 2 2 2 1 PAP2 superfamily EF-hand_7 PF13499.6 EKX51774.1 - 1e-16 61.2 1.0 2e-08 34.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX51774.1 - 1.1e-15 56.1 2.0 1.1e-05 25.0 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 EKX51774.1 - 1.1e-13 49.7 1.8 1.4e-05 24.3 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EKX51774.1 - 4.3e-07 29.7 1.1 0.00039 20.2 0.0 4.0 2 2 3 5 5 5 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX51774.1 - 1.9e-06 27.1 0.4 0.093 12.3 0.0 3.2 3 0 0 3 3 3 2 EF hand Dockerin_1 PF00404.18 EKX51774.1 - 0.056 13.6 0.1 1.7 8.9 0.0 2.3 2 0 0 2 2 2 0 Dockerin type I domain DUF5132 PF17195.4 EKX51774.1 - 0.13 12.4 0.7 0.99 9.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF5132) Dscam_C PF12355.8 EKX51775.1 - 0.16 12.9 1.9 13 6.7 2.5 2.3 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal VIR_N PF15912.5 EKX51775.1 - 0.41 10.2 3.4 0.73 9.4 3.4 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal PRIMA1 PF16101.5 EKX51775.1 - 3.7 7.6 6.3 8 6.5 6.3 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 EF-hand_6 PF13405.6 EKX51776.1 - 1.6e-10 40.1 1.1 0.00045 19.9 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EKX51776.1 - 2.6e-09 35.9 5.4 0.0004 19.7 0.8 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX51776.1 - 4.8e-09 36.6 6.2 0.0073 16.7 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX51776.1 - 2e-08 33.4 5.4 0.0013 18.1 0.4 2.9 2 0 0 2 2 2 2 EF hand Golgin_A5 PF09787.9 EKX51776.1 - 0.00035 20.1 22.4 0.00082 18.9 22.4 1.6 1 0 0 1 1 1 1 Golgin subfamily A member 5 EF-hand_8 PF13833.6 EKX51776.1 - 0.0072 16.2 2.3 2.7 7.9 0.4 2.7 2 0 0 2 2 2 2 EF-hand domain pair DUF4279 PF14106.6 EKX51776.1 - 3.2 8.0 7.1 2.7 8.2 1.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) Spc7 PF08317.11 EKX51776.1 - 3.3 6.5 33.2 2.5 6.9 19.3 2.6 1 1 1 2 2 2 0 Spc7 kinetochore protein APG6_N PF17675.1 EKX51776.1 - 3.8 8.0 35.5 0.73 10.4 10.4 3.4 1 1 2 3 3 3 0 Apg6 coiled-coil region FUSC PF04632.12 EKX51776.1 - 7.1 5.0 11.8 0.92 8.0 6.0 2.1 2 1 0 2 2 2 0 Fusaric acid resistance protein family Fez1 PF06818.15 EKX51776.1 - 8.3 6.8 31.6 2 8.8 21.3 2.5 1 1 1 2 2 2 0 Fez1 PDZ_6 PF17820.1 EKX51777.1 - 2.6e-08 33.6 0.0 8.6e-08 31.9 0.0 2.0 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX51777.1 - 6.6e-07 29.6 0.1 2.1e-06 28.0 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX51777.1 - 0.00053 20.3 0.0 0.0017 18.6 0.0 2.0 1 1 0 1 1 1 1 PDZ domain DUF1241 PF06840.11 EKX51777.1 - 0.0089 15.7 1.7 0.0089 15.7 1.7 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF1241) AAA_23 PF13476.6 EKX51777.1 - 0.015 15.8 9.6 0.015 15.8 9.6 4.1 2 1 0 2 2 2 0 AAA domain RIC3 PF15361.6 EKX51777.1 - 0.15 12.5 0.2 0.15 12.5 0.2 5.8 6 2 0 6 6 6 0 Resistance to inhibitors of cholinesterase homologue 3 Pkinase PF00069.25 EKX51778.1 - 9.1e-23 81.0 0.0 1.7e-10 40.7 0.0 3.6 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EKX51778.1 - 0.0044 16.3 0.3 0.31 10.3 0.1 3.0 1 1 1 2 2 2 1 Protein tyrosine kinase Radial_spoke PF04712.12 EKX51778.1 - 0.0099 14.9 0.8 0.0099 14.9 0.8 2.2 2 0 0 2 2 2 1 Radial spokehead-like protein Myc_N PF01056.18 EKX51778.1 - 0.064 13.2 11.4 0.21 11.5 2.3 2.3 2 0 0 2 2 2 0 Myc amino-terminal region Tyosinase_C PF18132.1 EKX51778.1 - 0.16 12.7 0.0 0.49 11.1 0.0 1.8 2 0 0 2 2 2 0 Tyosinase C-terminal domain FAM176 PF14851.6 EKX51778.1 - 0.93 9.1 8.7 4.6 6.9 0.6 2.6 2 0 0 2 2 2 0 FAM176 family RNA_pol_3_Rpc31 PF11705.8 EKX51778.1 - 6.2 7.0 13.9 2.7 8.2 2.4 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Peptidase_M13_N PF05649.13 EKX51779.1 - 6.8e-66 223.5 0.2 1.1e-65 222.9 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 EKX51779.1 - 1.7e-61 207.4 0.0 3.4e-61 206.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M13 Phycobilisome PF00502.19 EKX51781.1 - 0.5 10.3 6.4 0.067 13.1 1.0 2.4 2 0 0 2 2 2 0 Phycobilisome protein ATP-synt_B PF00430.18 EKX51782.1 - 2.9 8.0 7.6 7 6.8 7.6 1.6 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Neur_chan_memb PF02932.16 EKX51782.1 - 6.7 6.7 5.5 10 6.1 5.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region N2227 PF07942.12 EKX51783.1 - 0.069 12.3 0.0 0.2 10.8 0.0 1.8 1 0 0 1 1 1 0 N2227-like protein Baculo_PEP_C PF04513.12 EKX51783.1 - 1.4 9.0 6.0 10 6.2 0.2 3.5 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nipped-B_C PF12830.7 EKX51783.1 - 5.9 6.8 7.8 0.77 9.7 0.3 2.8 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus PH PF00169.29 EKX51784.1 - 2.7e-05 24.6 0.0 6.9e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 PH domain Arm PF00514.23 EKX51785.1 - 7.4e-59 194.1 16.7 3.4e-08 33.2 0.1 7.4 7 0 0 7 7 7 7 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EKX51785.1 - 2.1e-13 50.5 15.5 0.11 13.1 1.6 7.0 4 2 3 7 7 7 5 HEAT-like repeat HEAT_2 PF13646.6 EKX51785.1 - 7.6e-11 42.3 13.6 0.0001 22.6 3.0 4.4 1 1 3 5 5 5 4 HEAT repeats Arm_2 PF04826.13 EKX51785.1 - 2.9e-10 40.0 0.4 2.6e-05 23.8 0.8 3.9 1 1 2 3 3 3 2 Armadillo-like Adaptin_N PF01602.20 EKX51785.1 - 2.6e-07 29.6 1.9 0.00022 19.9 0.1 2.0 1 1 1 2 2 2 2 Adaptin N terminal region HEAT PF02985.22 EKX51785.1 - 4.5e-07 29.6 7.6 0.21 11.9 0.0 6.5 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.7 EKX51785.1 - 2.8e-06 27.5 0.0 0.0025 17.9 0.2 3.0 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 EKX51785.1 - 0.00035 20.5 1.1 0.084 12.8 0.0 3.4 1 1 3 4 4 4 1 Domain of unknown function (DUF3361) KAP PF05804.12 EKX51785.1 - 0.0015 16.8 0.0 0.037 12.2 0.0 2.1 1 1 0 2 2 2 1 Kinesin-associated protein (KAP) V-ATPase_H_C PF11698.8 EKX51785.1 - 0.0016 18.6 1.3 0.12 12.5 0.1 3.3 1 1 2 3 3 3 1 V-ATPase subunit H RasGEF_N_2 PF14663.6 EKX51785.1 - 0.0057 17.0 2.6 29 5.1 0.1 3.9 1 1 2 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain CSRNP_N PF16019.5 EKX51785.1 - 0.83 9.5 3.4 1.8 8.4 3.4 1.5 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Mur_ligase_M PF08245.12 EKX51786.1 - 0.00012 22.2 0.0 0.00045 20.3 0.0 1.9 1 1 0 1 1 1 1 Mur ligase middle domain Bac_rhodopsin PF01036.18 EKX51787.1 - 8.1e-43 146.6 25.0 1.1e-42 146.2 25.0 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein zf-RING_9 PF13901.6 EKX51788.1 - 1.5e-46 159.0 2.9 2.6e-46 158.2 2.9 1.3 1 0 0 1 1 1 1 Putative zinc-RING and/or ribbon RUN PF02759.19 EKX51788.1 - 2.6e-08 33.9 0.0 7.2e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 RUN domain CDT1_C PF16679.5 EKX51788.1 - 0.047 14.1 0.1 0.14 12.6 0.1 1.9 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain C1_2 PF03107.16 EKX51788.1 - 0.081 13.3 5.2 1.1 9.6 0.2 2.9 2 0 0 2 2 2 0 C1 domain DUF1003 PF06210.11 EKX51788.1 - 0.3 11.2 0.1 0.3 11.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) zf-RING_2 PF13639.6 EKX51789.1 - 7.7e-15 55.0 7.3 9e-15 54.7 7.3 1.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EKX51789.1 - 6e-12 45.1 2.4 6e-12 45.1 2.4 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EKX51789.1 - 6.7e-11 41.9 7.4 8.4e-11 41.5 7.4 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX51789.1 - 2.6e-09 36.8 6.1 3.5e-09 36.4 6.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX51789.1 - 1.2e-08 35.1 10.2 3.3e-08 33.7 10.2 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EKX51789.1 - 4.8e-08 32.9 1.5 4.8e-08 32.9 1.5 1.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EKX51789.1 - 5.7e-07 29.3 4.7 6.9e-07 29.0 4.7 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX51789.1 - 1.1e-06 28.5 5.0 1.4e-06 28.2 5.0 1.2 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EKX51789.1 - 3.1e-05 23.7 5.2 4.3e-05 23.3 5.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EKX51789.1 - 0.00049 20.1 7.1 0.0021 18.1 7.1 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EKX51789.1 - 0.00049 19.7 5.2 0.00075 19.1 5.2 1.3 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EKX51789.1 - 0.0042 17.2 8.9 0.0098 16.0 6.0 2.4 1 1 1 2 2 2 1 FANCL C-terminal domain zf-C3H2C3 PF17122.5 EKX51789.1 - 0.059 13.4 5.1 0.059 13.4 5.1 1.9 2 1 0 2 2 1 0 Zinc-finger zf-RING-like PF08746.11 EKX51789.1 - 0.064 13.6 7.0 0.11 12.8 6.4 1.7 1 1 1 2 2 2 0 RING-like domain RINGv PF12906.7 EKX51789.1 - 0.071 13.2 10.0 0.32 11.1 9.6 2.0 1 1 1 2 2 2 0 RING-variant domain zinc_ribbon_16 PF17034.5 EKX51789.1 - 0.075 13.3 3.2 0.086 13.1 3.2 1.4 1 1 0 1 1 1 0 Zinc-ribbon like family zf-Nse PF11789.8 EKX51789.1 - 0.092 12.6 3.1 0.11 12.3 3.1 1.2 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 EKX51789.1 - 0.52 10.5 7.3 4.5 7.5 7.3 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING PGAP1 PF07819.13 EKX51792.1 - 6.3e-08 32.6 0.0 1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 EKX51792.1 - 1.5e-05 24.8 0.0 6.3e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 EKX51792.1 - 0.00012 22.1 0.0 0.00013 21.9 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 EKX51792.1 - 0.00037 19.9 0.0 0.00062 19.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.25 EKX51792.1 - 0.0017 18.2 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 EKX51792.1 - 0.0018 17.8 0.0 0.0029 17.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EKX51792.1 - 0.0021 18.7 0.0 0.004 17.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EKX51792.1 - 0.0041 16.4 0.0 0.0076 15.5 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LCAT PF02450.15 EKX51792.1 - 0.024 13.8 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase LIDHydrolase PF10230.9 EKX51792.1 - 0.046 13.3 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase SHIPPO-rpt PF07004.12 EKX51795.1 - 0.08 13.9 0.1 0.22 12.5 0.1 1.8 1 0 0 1 1 1 0 Sperm-tail PG-rich repeat TPH PF13868.6 EKX51795.1 - 0.7 8.3 105.0 0.04 12.4 44.6 2.5 2 1 0 2 2 2 0 Trichohyalin-plectin-homology domain Beta_helix PF13229.6 EKX51796.1 - 3.2e-32 111.5 24.6 1.3e-16 60.8 11.6 3.2 2 1 0 2 2 2 2 Right handed beta helix region NosD PF05048.13 EKX51796.1 - 1.5e-27 96.4 7.9 1.1e-19 70.7 3.4 2.2 2 0 0 2 2 2 2 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.7 EKX51796.1 - 0.0041 17.0 10.7 0.12 12.1 0.2 4.0 2 2 1 4 4 4 3 Pectate lyase superfamily protein DUF5577 PF17740.1 EKX51797.1 - 0.025 14.3 0.8 0.042 13.5 0.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5577) TPR_12 PF13424.6 EKX51798.1 - 2.6e-15 56.5 7.2 2.3e-07 31.0 0.9 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX51798.1 - 7.3e-14 50.9 4.7 5.4e-05 22.8 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX51798.1 - 1.3e-11 43.9 10.0 0.00061 19.6 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX51798.1 - 1.3e-08 34.4 3.4 0.0064 16.6 0.1 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX51798.1 - 1.6e-08 34.0 10.7 0.00069 19.5 0.2 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX51798.1 - 0.0023 17.9 2.5 1.2 9.3 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX51798.1 - 0.0043 17.8 4.7 3.4 8.8 0.0 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX51798.1 - 0.02 14.5 1.3 2.1 8.1 0.1 2.7 2 0 0 2 2 2 0 TPR repeat TPR_17 PF13431.6 EKX51798.1 - 0.035 14.5 0.4 8.4 7.0 0.0 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 EKX51798.1 - 0.48 10.5 6.5 0.71 10.0 0.3 3.3 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_4 PF07721.14 EKX51798.1 - 7.8 7.4 8.7 7.7 7.5 0.4 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat UBA PF00627.31 EKX51799.1 - 2e-06 27.6 0.7 0.018 14.9 0.2 3.0 3 0 0 3 3 3 2 UBA/TS-N domain UBA_3 PF09288.10 EKX51799.1 - 0.00016 21.4 0.0 0.14 12.0 0.0 2.6 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain UBA_2 PF08587.11 EKX51799.1 - 0.0022 18.1 0.1 1.6 8.9 0.1 3.2 3 0 0 3 3 3 2 Ubiquitin associated domain (UBA) Glycolytic PF00274.19 EKX51801.1 - 5.4e-142 472.6 0.0 6e-142 472.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I BLM10_mid PF16507.5 EKX51802.1 - 6.2e-68 229.7 4.3 1.2e-50 172.7 1.1 3.4 2 1 0 2 2 2 2 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EKX51802.1 - 3.3e-31 107.0 0.3 5.2e-30 103.2 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) CLASP_N PF12348.8 EKX51802.1 - 3.5e-07 30.0 0.7 0.0002 21.0 0.1 2.9 2 0 0 2 2 2 2 CLASP N terminal HEAT_EZ PF13513.6 EKX51802.1 - 0.0028 18.1 5.5 15 6.2 0.1 6.0 5 0 0 5 5 5 1 HEAT-like repeat MMS19_C PF12460.8 EKX51802.1 - 0.013 14.7 1.3 0.39 9.8 0.5 2.7 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal HEAT PF02985.22 EKX51802.1 - 0.018 15.3 7.0 6.6 7.3 0.1 5.8 5 0 0 5 5 5 0 HEAT repeat HEAT_2 PF13646.6 EKX51802.1 - 0.23 11.9 2.4 14 6.2 0.2 4.2 4 1 1 5 5 5 0 HEAT repeats XPC-binding PF09280.11 EKX51802.1 - 0.25 11.1 1.2 1.3 8.8 1.2 2.3 1 0 0 1 1 1 0 XPC-binding domain RWP-RK PF02042.15 EKX51803.1 - 1.4e-16 60.2 0.0 2.1e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX51804.1 - 1.3e-16 60.3 0.0 1.8e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 RWP-RK domain DUF2475 PF10629.9 EKX51805.1 - 3.9e-15 55.8 3.4 1.1e-05 25.5 0.1 4.1 4 0 0 4 4 4 2 Protein of unknown function (DUF2475) SPATA48 PF15073.6 EKX51805.1 - 0.39 11.0 4.0 1.6 9.0 0.1 2.7 3 0 0 3 3 3 0 Spermatogenesis-associated protein 48 FGE-sulfatase PF03781.16 EKX51807.1 - 7.4e-28 97.8 0.0 2.1e-27 96.3 0.0 1.7 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Methyltransf_23 PF13489.6 EKX51807.1 - 1.8e-08 34.4 0.0 4.3e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX51807.1 - 1.5e-07 31.4 0.0 1.5e-05 24.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX51807.1 - 3.3e-06 27.7 0.1 1.4e-05 25.6 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX51807.1 - 1.4e-05 25.7 0.2 0.00024 21.8 0.2 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX51807.1 - 0.00096 19.9 0.0 0.0031 18.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain DinB_2 PF12867.7 EKX51807.1 - 0.0057 17.2 0.0 0.011 16.3 0.0 1.5 1 0 0 1 1 1 1 DinB superfamily Methyltransf_4 PF02390.17 EKX51807.1 - 0.027 14.0 0.0 2 7.9 0.0 2.3 2 0 0 2 2 2 0 Putative methyltransferase Med7 PF05983.11 EKX51807.1 - 0.047 13.8 0.0 0.082 13.0 0.0 1.3 1 0 0 1 1 1 0 MED7 protein Ribosomal_S7 PF00177.21 EKX51810.1 - 2.4e-38 131.1 2.4 2.9e-38 130.8 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SH3_9 PF14604.6 EKX51811.1 - 1.6e-15 56.7 0.8 2.7e-15 55.9 0.8 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EKX51811.1 - 1.4e-14 53.4 0.3 2.3e-14 52.7 0.3 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EKX51811.1 - 5.1e-14 51.7 0.0 9.5e-14 50.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Exonuc_VII_L PF02601.15 EKX51811.1 - 0.29 10.7 9.2 0.38 10.3 9.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit SOAR PF16533.5 EKX51811.1 - 0.56 10.2 7.5 0.89 9.6 7.0 1.6 1 1 0 1 1 1 0 STIM1 Orai1-activating region DUF4407 PF14362.6 EKX51811.1 - 2 7.7 9.7 2.8 7.2 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Neur_chan_LBD PF02931.23 EKX51812.1 - 0.00078 19.0 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel ligand binding domain Peptidase_U4 PF03419.13 EKX51812.1 - 0.045 13.0 0.6 0.072 12.4 0.6 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DUF4870 PF09685.10 EKX51812.1 - 0.7 10.0 4.7 3.1 7.9 3.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) DUF2304 PF10066.9 EKX51812.1 - 1.5 9.1 5.1 4.1 7.7 5.1 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) V-SNARE_C PF12352.8 EKX51814.1 - 1.4e-17 63.7 4.1 1.6e-17 63.6 2.5 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EKX51814.1 - 6e-07 29.3 0.4 6e-07 29.3 0.4 2.7 3 1 0 3 3 3 1 Sec20 V-SNARE PF05008.15 EKX51814.1 - 0.018 15.4 0.2 0.018 15.4 0.2 2.7 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF3206 PF11472.8 EKX51814.1 - 0.039 13.9 0.1 0.067 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) PIN_2 PF10130.9 EKX51814.1 - 0.15 12.3 1.8 0.3 11.3 0.2 2.1 2 1 0 2 2 2 0 PIN domain DUF4643 PF15485.6 EKX51816.1 - 0.34 10.7 11.1 0.36 10.6 11.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) UPF0172 PF03665.13 EKX51817.1 - 0.035 14.2 0.4 0.036 14.1 0.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) Seryl_tRNA_N PF02403.22 EKX51817.1 - 0.31 11.3 11.9 0.09 13.0 8.9 1.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 EKX51817.1 - 5.9 7.4 16.6 8.3 7.0 16.6 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF3458_C PF17432.2 EKX51818.1 - 9.7e-107 357.0 6.4 1.4e-106 356.5 6.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 EKX51818.1 - 1.7e-50 171.6 0.1 3e-50 170.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain DUF3458 PF11940.8 EKX51818.1 - 3.3e-27 94.8 0.0 6.9e-27 93.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 EKX51818.1 - 1.3e-15 58.1 0.0 2.2e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain tRNA_NucTran2_2 PF13735.6 EKX51818.1 - 0.06 13.3 0.5 0.16 12.0 0.5 1.7 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Peptidase_M61 PF05299.12 EKX51818.1 - 0.16 12.4 0.0 0.42 11.0 0.0 1.8 1 0 0 1 1 1 0 M61 glycyl aminopeptidase VPS9 PF02204.18 EKX51819.1 - 2.8e-13 50.0 0.0 5.2e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Phi_1 PF04674.12 EKX51820.1 - 0.022 14.1 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region LPD37 PF18853.1 EKX51820.1 - 0.12 11.9 0.0 0.45 10.0 0.0 1.7 2 0 0 2 2 2 0 Large polyvalent protein associated domain 37 Wzy_C PF04932.15 EKX51821.1 - 0.0041 16.7 0.1 0.0046 16.6 0.1 1.2 1 0 0 1 1 1 1 O-Antigen ligase Sarcoglycan_1 PF04790.13 EKX51821.1 - 0.015 14.6 2.3 0.028 13.8 2.3 1.4 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein DUF3726 PF12525.8 EKX51821.1 - 0.11 12.6 1.4 0.18 12.0 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3726) CbiQ PF02361.16 EKX51821.1 - 0.2 11.2 8.0 0.28 10.8 8.0 1.2 1 0 0 1 1 1 0 Cobalt transport protein LNS2 PF08235.13 EKX51822.1 - 3.6e-24 85.5 0.0 4.2e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Pkinase PF00069.25 EKX51823.1 - 4.5e-63 213.1 0.0 5.2e-63 212.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX51823.1 - 4.8e-27 94.9 0.0 6.4e-27 94.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX51823.1 - 2.3e-05 23.9 0.0 2.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EKX51823.1 - 0.0025 17.5 0.0 0.0041 16.8 0.0 1.5 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EKX51823.1 - 0.0064 15.9 0.1 0.013 14.8 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EKX51823.1 - 0.019 13.8 0.1 0.035 12.9 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 EKX51823.1 - 0.067 12.1 0.1 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 EKX51823.1 - 0.11 12.4 0.8 0.41 10.5 0.1 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family FTR1 PF03239.14 EKX51825.1 - 3.7e-26 92.0 7.3 2.5e-13 49.9 0.1 2.1 1 1 1 2 2 2 2 Iron permease FTR1 family DUF2207 PF09972.9 EKX51825.1 - 1.3 7.7 10.0 0.99 8.1 0.3 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) FUN14 PF04930.15 EKX51825.1 - 1.4 9.4 6.3 0.57 10.6 2.4 2.3 2 1 0 2 2 2 0 FUN14 family Phage_holin_3_6 PF07332.11 EKX51825.1 - 2.6 8.1 13.9 0.5 10.4 0.6 3.1 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III adh_short_C2 PF13561.6 EKX51826.1 - 4.1e-53 180.3 2.3 1.6e-51 175.1 2.3 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EKX51826.1 - 7.4e-49 165.9 1.0 9.3e-49 165.5 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EKX51826.1 - 1.2e-11 44.9 1.3 2.7e-10 40.5 1.3 2.1 1 1 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 EKX51826.1 - 0.0086 16.2 0.2 0.015 15.4 0.2 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ADH_zinc_N PF00107.26 EKX51826.1 - 0.032 14.2 0.4 1 9.4 0.4 2.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase 3HCDH_N PF02737.18 EKX51826.1 - 0.093 12.6 0.2 0.19 11.6 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EKX51826.1 - 0.27 10.6 1.3 0.29 10.5 0.2 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PAPS_reduct PF01507.19 EKX51827.1 - 1.5e-39 135.8 0.0 1.7e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family zf-C3HC4_3 PF13920.6 EKX51828.1 - 0.00047 20.0 2.2 0.00073 19.3 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX51828.1 - 0.0014 18.4 1.5 0.0025 17.6 1.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EKX51828.1 - 0.0074 16.1 4.1 0.012 15.4 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX51828.1 - 0.0087 16.4 4.9 0.015 15.6 4.9 1.4 1 0 0 1 1 1 1 Ring finger domain TetR_C_6 PF13977.6 EKX51828.1 - 0.011 15.9 0.0 0.02 15.1 0.0 1.5 1 1 0 1 1 1 0 BetI-type transcriptional repressor, C-terminal Spt4 PF06093.13 EKX51828.1 - 0.026 14.6 0.3 0.19 11.9 0.3 2.1 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger zf-P11 PF03854.14 EKX51828.1 - 0.036 13.7 0.3 0.066 12.9 0.3 1.4 1 0 0 1 1 1 0 P-11 zinc finger DUF1924 PF09086.11 EKX51828.1 - 0.2 12.1 0.1 0.2 12.1 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1924) HECT PF00632.25 EKX51829.1 - 5.1e-32 111.6 0.0 1.2e-31 110.4 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ank_2 PF12796.7 EKX51829.1 - 1.6e-07 31.8 0.1 5.3e-07 30.1 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX51829.1 - 3.5e-07 30.4 0.2 0.00031 21.0 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX51829.1 - 3.6e-06 27.4 0.2 0.015 15.8 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX51829.1 - 6e-05 23.3 0.8 1.1 9.9 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EKX51829.1 - 0.00033 20.9 0.1 0.28 11.9 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat F420_oxidored PF03807.17 EKX51830.1 - 7.2e-15 55.4 0.0 5e-14 52.7 0.0 2.1 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EKX51830.1 - 8.3e-06 25.9 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase P5CR_dimer PF14748.6 EKX51830.1 - 3.9e-05 23.9 0.0 6.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation GFO_IDH_MocA PF01408.22 EKX51830.1 - 0.00016 22.5 0.0 0.00026 21.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 EKX51830.1 - 0.0053 17.0 0.1 0.0091 16.3 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain OCD_Mu_crystall PF02423.15 EKX51830.1 - 0.04 12.9 0.1 0.056 12.4 0.1 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family B12-binding PF02310.19 EKX51830.1 - 0.096 12.7 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain CDP-OH_P_transf PF01066.21 EKX51831.1 - 1.9e-12 47.8 1.7 1.9e-12 47.8 1.7 2.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF4022 PF13214.6 EKX51831.1 - 0.32 11.3 0.1 0.32 11.3 0.1 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF4022) DIE2_ALG10 PF04922.12 EKX51832.1 - 6.7e-47 160.6 16.3 5.4e-29 101.7 2.3 2.5 1 1 1 2 2 2 2 DIE2/ALG10 family DUF883 PF05957.13 EKX51834.1 - 0.044 14.4 1.7 0.78 10.4 0.0 3.5 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF883) PriC PF07445.12 EKX51834.1 - 1.3 8.9 10.1 2.8 7.8 10.1 1.8 1 1 0 1 1 1 0 Primosomal replication protein priC PsaA_PsaB PF00223.19 EKX51835.1 - 0.11 10.7 0.1 0.15 10.2 0.1 1.2 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein RhoGAP PF00620.27 EKX51836.1 - 1.2e-12 47.9 1.2 1.7e-12 47.4 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain Ank_4 PF13637.6 EKX51836.1 - 1.5e-11 44.5 0.5 0.00073 20.1 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX51836.1 - 6.8e-09 36.2 0.0 1.3e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX51836.1 - 1.2e-08 35.1 0.2 3.7e-08 33.5 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX51836.1 - 6.8e-06 26.3 0.0 0.0055 17.1 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EKX51836.1 - 0.00029 21.0 0.2 0.041 14.4 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat TSC22 PF01166.18 EKX51836.1 - 0.013 15.8 0.3 0.048 14.0 0.3 2.0 1 0 0 1 1 1 0 TSC-22/dip/bun family Kinesin PF00225.23 EKX51837.1 - 3.5e-48 164.2 0.0 3.5e-48 164.2 0.0 2.9 4 0 0 4 4 4 1 Kinesin motor domain DUF4472 PF14739.6 EKX51837.1 - 6.6e-24 84.7 14.5 6.6e-24 84.7 14.5 6.2 5 1 2 7 7 7 2 Domain of unknown function (DUF4472) Microtub_bd PF16796.5 EKX51837.1 - 5.9e-09 36.0 0.1 5.9e-09 36.0 0.1 4.0 3 2 0 3 3 3 1 Microtubule binding DUF819 PF05684.12 EKX51838.1 - 1.4e-50 172.4 22.0 2.8e-50 171.4 22.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF819) Na_H_Exchanger PF00999.21 EKX51838.1 - 0.00073 18.4 7.8 0.00073 18.4 7.8 2.3 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family Glt_symporter PF03616.14 EKX51838.1 - 0.0022 16.8 5.5 0.0022 16.8 5.5 1.8 2 1 0 2 2 2 1 Sodium/glutamate symporter CLIP1_ZNF PF16641.5 EKX51839.1 - 0.1 12.5 2.3 0.16 11.9 2.3 1.3 1 0 0 1 1 1 0 CLIP1 zinc knuckle GAF PF01590.26 EKX51840.1 - 1.8e-14 54.5 0.1 1.2e-09 38.9 0.0 2.4 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 EKX51840.1 - 3.1e-10 40.5 0.0 2e-08 34.6 0.0 2.3 2 0 0 2 2 2 1 GAF domain DUF5411 PF17424.2 EKX51840.1 - 0.18 11.8 0.3 26 4.8 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5411) PhyH PF05721.13 EKX51841.1 - 0.001 19.4 0.1 0.039 14.2 0.0 2.4 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) TRAPPC-Trs85 PF12739.7 EKX51845.1 - 5.6e-70 236.4 0.0 3.8e-51 174.3 0.0 2.4 1 1 1 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.11 EKX51845.1 - 2.9e-06 25.0 0.0 4.1e-06 24.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_10 PF13374.6 EKX51845.1 - 0.024 14.5 0.0 11 6.1 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EKX51845.1 - 0.44 10.8 1.4 23 5.4 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat COX6A PF02046.15 EKX51846.1 - 5.3e-08 33.3 0.0 6.2e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa AhpC-TSA PF00578.21 EKX51847.1 - 1.3e-22 80.0 0.0 1.7e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EKX51847.1 - 3.2e-21 75.6 0.0 4.1e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 EKX51847.1 - 2.4e-16 59.8 0.0 3.3e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 EKX51847.1 - 3.8e-09 36.5 0.1 2.9e-08 33.6 0.2 2.1 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 EKX51847.1 - 3.8e-08 33.8 0.0 5.5e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.6 EKX51847.1 - 0.019 15.1 0.1 0.039 14.1 0.0 1.4 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_9 PF14595.6 EKX51847.1 - 0.073 12.9 0.0 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin Pns11_12 PF17464.2 EKX51848.1 - 0.079 12.7 5.0 0.12 12.0 5.0 1.2 1 0 0 1 1 1 0 Non-structural protein 11 and 12 RVT_1 PF00078.27 EKX51849.1 - 1.4e-07 31.3 0.0 6.6e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) DEC-1_N PF04625.13 EKX51849.1 - 0.21 10.6 1.4 0.31 10.0 1.4 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF5486 PF17588.2 EKX51849.1 - 0.25 11.2 0.4 0.67 9.9 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5486) Cytochrome_CBB3 PF13442.6 EKX51851.1 - 2.8e-17 62.8 0.1 8.8e-17 61.2 0.1 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EKX51851.1 - 3.2e-08 34.6 0.2 1.1e-07 32.9 0.2 1.9 1 1 0 1 1 1 1 Cytochrome c Cytochrom_C550 PF14495.6 EKX51851.1 - 8e-08 32.1 0.1 1.1e-05 25.2 0.1 2.1 1 1 1 2 2 2 2 Cytochrome c-550 domain Cytochrome-c551 PF10643.9 EKX51851.1 - 0.081 12.5 2.2 0.26 10.8 2.2 1.7 1 1 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 HNH_5 PF14279.6 EKX51852.1 - 4.2e-13 48.9 0.3 7.6e-13 48.1 0.3 1.4 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.23 EKX51852.1 - 1.3e-12 47.7 0.0 2.2e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 EKX51852.1 - 0.0001 22.1 0.0 0.00064 19.6 0.0 2.2 3 0 0 3 3 3 1 HNH endonuclease PB1 PF00564.24 EKX51853.1 - 1.3e-09 37.8 3.1 0.00043 20.2 0.1 3.9 3 0 0 3 3 3 2 PB1 domain PyrI_C PF02748.15 EKX51853.1 - 2.4 8.1 8.8 7.7 6.5 0.1 3.6 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Tweety PF04906.13 EKX51853.1 - 4.7 5.8 6.9 1.5 7.4 2.4 2.2 1 1 1 2 2 2 0 Tweety AMP-binding_C_2 PF14535.6 EKX51853.1 - 5.9 7.3 14.2 0.15 12.4 1.6 4.1 3 1 1 4 4 4 0 AMP-binding enzyme C-terminal domain Bromodomain PF00439.25 EKX51854.1 - 8.2e-19 67.5 0.0 8.5e-19 67.4 0.0 1.0 1 0 0 1 1 1 1 Bromodomain Hat1_N PF10394.9 EKX51854.1 - 0.063 13.5 0.0 0.069 13.4 0.0 1.0 1 0 0 1 1 1 0 Histone acetyl transferase HAT1 N-terminus DEAD PF00270.29 EKX51855.1 - 3e-45 154.1 0.0 5.6e-45 153.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX51855.1 - 1.8e-14 54.0 0.0 8.1e-14 51.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GUCT PF08152.12 EKX51855.1 - 9e-13 48.3 0.0 2.2e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 GUCT (NUC152) domain UVR PF02151.19 EKX51855.1 - 0.00019 21.0 5.5 0.00044 19.9 5.5 1.6 1 0 0 1 1 1 1 UvrB/uvrC motif ResIII PF04851.15 EKX51855.1 - 0.0011 19.1 0.0 0.0033 17.5 0.0 1.8 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EKX51855.1 - 0.0072 15.7 0.1 0.0072 15.7 0.1 2.3 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit SecA_DEAD PF07517.14 EKX51855.1 - 0.044 13.1 0.1 0.082 12.2 0.1 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain TPR_2 PF07719.17 EKX51857.1 - 1.2e-32 109.4 16.1 2.3e-05 24.2 0.1 10.3 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_1 PF00515.28 EKX51857.1 - 3.7e-30 102.5 20.4 1.2e-05 24.9 0.0 9.8 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 EKX51857.1 - 2.2e-24 83.6 7.8 0.026 14.7 0.1 9.2 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.6 EKX51857.1 - 4.2e-20 71.8 9.6 2.1e-08 34.3 0.1 7.8 7 1 2 9 9 9 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX51857.1 - 5.3e-16 58.6 26.8 4.4e-13 49.2 0.7 5.7 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EKX51857.1 - 1.2e-13 50.5 0.0 0.0075 15.9 0.0 6.4 5 1 1 6 6 6 3 TPR repeat TPR_7 PF13176.6 EKX51857.1 - 1.6e-12 46.5 7.0 0.1 12.7 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 EKX51857.1 - 2.5e-12 47.2 1.5 0.037 14.7 0.2 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 EKX51857.1 - 5.8e-12 45.1 0.6 0.84 9.6 0.0 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 EKX51857.1 - 8.4e-12 44.9 2.3 0.78 10.7 0.0 7.6 5 2 3 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX51857.1 - 3.2e-11 43.6 2.1 0.021 15.3 0.1 5.9 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX51857.1 - 2e-08 34.3 12.9 0.11 13.2 0.0 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX51857.1 - 1.7e-07 31.3 0.4 0.0056 16.8 0.1 4.4 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX51857.1 - 6.2e-05 23.1 5.5 11 6.7 0.2 7.0 7 1 0 7 7 6 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EKX51857.1 - 7.8e-05 22.7 5.1 0.0012 18.8 0.0 3.8 4 1 0 4 4 4 1 Putative TPR-like repeat TPR_21 PF09976.9 EKX51857.1 - 0.00012 21.8 5.7 0.024 14.3 2.8 4.2 4 1 0 4 4 3 1 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 EKX51857.1 - 0.00016 21.2 0.2 0.0053 16.2 0.0 3.1 2 2 2 4 4 4 1 MalT-like TPR region ANAPC8 PF04049.13 EKX51857.1 - 0.00047 20.2 0.2 0.00047 20.2 0.2 2.8 3 1 0 3 3 3 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_3 PF07720.12 EKX51857.1 - 0.0018 18.2 17.4 0.0021 18.0 0.3 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat DiSB-ORF2_chro PF16506.5 EKX51857.1 - 0.0037 17.2 0.0 0.014 15.4 0.0 2.0 1 0 0 1 1 1 1 Putative virion glycoprotein of insect viruses HIT PF01230.23 EKX51858.1 - 3.6e-25 88.6 0.5 7.6e-25 87.5 0.5 1.6 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 EKX51858.1 - 4.1e-24 85.3 0.3 6.5e-24 84.6 0.3 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GST_N_3 PF13417.6 EKX51858.1 - 3.2e-14 53.1 0.0 7.2e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EKX51858.1 - 6.4e-08 32.8 0.0 1.9e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EKX51858.1 - 3.1e-05 23.9 0.1 7.6e-05 22.7 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EKX51858.1 - 5.4e-05 23.4 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EKX51858.1 - 0.00084 19.5 0.0 0.0019 18.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EKX51858.1 - 0.0092 16.6 0.0 0.018 15.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EKX51858.1 - 0.01 16.0 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pkinase PF00069.25 EKX51859.1 - 7.5e-68 228.7 0.0 9.1e-68 228.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX51859.1 - 8.9e-33 113.7 0.0 1.2e-32 113.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX51859.1 - 2e-09 37.2 0.0 2.2e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EKX51859.1 - 0.00012 21.5 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX51859.1 - 0.0039 17.2 0.0 0.0055 16.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EKX51859.1 - 0.0055 16.3 0.1 0.0093 15.6 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 EKX51859.1 - 0.0064 15.3 0.0 0.0083 14.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EKX51859.1 - 0.083 11.8 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Ank_2 PF12796.7 EKX51860.1 - 1.1e-31 109.2 0.5 1.3e-08 35.3 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX51860.1 - 4.2e-30 103.7 0.9 5.6e-09 36.4 0.0 4.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX51860.1 - 5.5e-26 90.3 5.1 5.4e-11 42.5 0.1 5.3 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EKX51860.1 - 6.1e-26 89.7 11.1 6.2e-05 23.3 0.3 6.8 6 1 1 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 EKX51860.1 - 2.8e-22 76.4 6.7 0.0011 19.3 0.4 7.5 6 1 1 7 7 7 6 Ankyrin repeat BST2 PF16716.5 EKX51860.1 - 0.2 12.2 7.9 0.82 10.3 7.9 2.1 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 S-antigen PF05756.11 EKX51860.1 - 6.5 7.2 10.9 4.9 7.6 4.5 2.5 2 0 0 2 2 2 0 S-antigen protein ERG4_ERG24 PF01222.17 EKX51861.1 - 2.1e-134 448.5 7.0 2.4e-134 448.4 7.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Gln-synt_C PF00120.24 EKX51862.1 - 3.2e-17 62.6 0.0 5.7e-13 48.6 0.0 2.2 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EKX51862.1 - 3e-08 33.3 0.0 5.3e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF4880 PF16220.5 EKX51863.1 - 0.029 14.3 0.4 0.061 13.2 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4880) DUF4666 PF15697.5 EKX51863.1 - 0.28 11.9 4.1 0.24 12.1 1.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) HU-CCDC81_euk_2 PF18289.1 EKX51864.1 - 0.00054 20.1 0.0 0.00058 19.9 0.0 1.1 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 PMI_typeI PF01238.21 EKX51865.1 - 2.4e-104 349.5 0.0 2.6e-104 349.4 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I NHL PF01436.21 EKX51866.1 - 2.5e-18 65.1 0.5 0.0008 19.3 0.0 4.8 4 0 0 4 4 4 3 NHL repeat SGL PF08450.12 EKX51866.1 - 8.9e-13 48.4 0.3 0.0063 16.1 0.0 4.9 3 1 1 4 4 4 3 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 EKX51866.1 - 2e-11 43.9 0.0 0.53 10.5 0.0 4.3 4 0 0 4 4 4 4 Arylesterase Lactonase PF10282.9 EKX51866.1 - 1.9e-08 33.9 0.0 2.3e-06 27.1 0.0 2.5 1 1 2 3 3 3 2 Lactonase, 7-bladed beta-propeller PD40 PF07676.12 EKX51866.1 - 8.7e-05 22.3 2.2 4.7 7.3 0.0 4.5 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat SH3_6 PF12913.7 EKX51866.1 - 0.0046 16.5 0.0 3.9 7.1 0.0 3.3 3 0 0 3 3 3 1 SH3 domain (SH3b1 type) WD40 PF00400.32 EKX51866.1 - 0.0055 17.5 1.1 13 6.9 0.1 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat Str_synth PF03088.16 EKX51866.1 - 0.013 15.6 0.0 68 3.7 0.0 4.2 5 0 0 5 5 5 0 Strictosidine synthase LVIVD PF08309.11 EKX51866.1 - 0.02 14.2 0.5 35 3.8 0.0 4.0 4 0 0 4 4 4 0 LVIVD repeat VCBS PF13517.6 EKX51866.1 - 0.29 11.7 2.2 6.2 7.5 0.0 3.2 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Sel1 PF08238.12 EKX51867.1 - 7.3e-32 109.1 35.3 7e-05 23.4 0.3 12.1 13 0 0 13 13 13 8 Sel1 repeat ATP-synt_10 PF05176.14 EKX51868.1 - 1.9e-35 122.3 0.0 2.2e-35 122.1 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein MORN PF02493.20 EKX51869.1 - 3.5e-53 174.4 68.7 6.1e-08 32.1 5.4 9.3 9 0 0 9 9 9 8 MORN repeat rRNA_processing PF08524.11 EKX51869.1 - 0.2 11.7 10.4 0.43 10.6 10.4 1.6 1 0 0 1 1 1 0 rRNA processing eIF3_subunit PF08597.10 EKX51869.1 - 0.51 10.2 17.3 0.99 9.3 17.3 1.5 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF3048_C PF17479.2 EKX51869.1 - 0.96 9.9 25.3 14 6.1 0.2 5.4 2 1 3 5 5 5 0 Protein of unknown function (DUF3048) C-terminal domain XH PF03469.14 EKX51870.1 - 0.082 12.8 0.5 2.2 8.2 0.1 2.3 2 0 0 2 2 2 0 XH domain Atg14 PF10186.9 EKX51871.1 - 0.036 13.1 4.5 0.048 12.7 4.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TcpS PF17456.2 EKX51871.1 - 0.073 13.1 1.6 0.13 12.3 1.6 1.4 1 0 0 1 1 1 0 Toxin-coregulated pilus protein S Rotamase_3 PF13616.6 EKX51871.1 - 0.12 12.9 0.8 0.38 11.3 0.8 1.8 1 1 0 1 1 1 0 PPIC-type PPIASE domain CSN5_C PF18323.1 EKX51871.1 - 0.9 10.5 5.1 2.4 9.2 2.8 2.3 1 1 1 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain SEP PF08059.13 EKX51872.1 - 1.3e-11 44.9 0.1 3.6e-11 43.5 0.1 1.8 1 0 0 1 1 1 1 SEP domain PKcGMP_CC PF16808.5 EKX51872.1 - 0.13 12.2 0.3 0.13 12.2 0.3 2.7 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase YabA PF06156.13 EKX51872.1 - 0.5 11.0 2.3 0.89 10.2 0.3 2.4 2 0 0 2 2 2 0 Initiation control protein YabA DUF4407 PF14362.6 EKX51872.1 - 0.52 9.6 2.7 1 8.7 2.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.8 EKX51872.1 - 2.3 8.5 8.1 0.42 10.9 3.2 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF641 PF04859.12 EKX51872.1 - 2.6 8.4 6.9 0.31 11.4 1.0 2.5 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) NYD-SP28_assoc PF14775.6 EKX51872.1 - 3.7 7.7 10.3 1.6 8.9 0.5 3.4 3 1 1 4 4 4 0 Sperm tail C-terminal domain TRAPP PF04051.16 EKX51873.1 - 1.7e-39 134.8 0.1 2e-39 134.6 0.1 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Exo_endo_phos PF03372.23 EKX51874.1 - 7.4e-24 84.6 0.2 8.7e-24 84.3 0.2 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EKX51874.1 - 0.052 13.4 0.0 0.69 9.8 0.0 2.4 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Beach PF02138.18 EKX51876.1 - 6.8e-124 412.7 0.2 8e-124 412.5 0.2 1.0 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 EKX51876.1 - 3.4e-09 36.7 0.0 6.3e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH SBP PF03110.14 EKX51878.1 - 0.48 10.8 5.0 0.72 10.2 2.4 2.5 2 0 0 2 2 2 0 SBP domain Vac_Fusion PF02346.16 EKX51879.1 - 0.039 13.6 0.3 0.039 13.6 0.3 2.7 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 Shugoshin_N PF07558.11 EKX51879.1 - 0.058 13.3 9.3 0.096 12.6 1.1 4.1 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region Flagellin_N PF00669.20 EKX51879.1 - 0.08 13.0 3.8 0.33 11.1 3.8 2.1 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region Imm27 PF15590.6 EKX51879.1 - 0.083 12.7 0.3 0.37 10.6 0.3 2.1 1 0 0 1 1 1 0 Immunity protein 27 Fib_alpha PF08702.10 EKX51879.1 - 3.7 7.7 20.5 0.04 14.1 7.6 3.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF948 PF06103.11 EKX51879.1 - 7.3 6.9 8.4 8.6 6.7 3.4 3.3 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) MSA-2c PF12238.8 EKX51879.1 - 9.4 6.2 12.1 2.1 8.3 0.1 2.9 2 1 0 3 3 3 0 Merozoite surface antigen 2c PDZ PF00595.24 EKX51880.1 - 4.6e-07 30.1 0.6 8.1e-07 29.3 0.6 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX51880.1 - 4.5e-05 23.2 0.9 8.1e-05 22.4 0.3 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX51880.1 - 0.00011 22.4 2.0 0.00037 20.7 2.0 2.0 1 1 0 1 1 1 1 PDZ domain Bacillus_HBL PF05791.11 EKX51880.1 - 6.1 6.6 12.6 0.037 13.8 2.3 2.3 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) PH_12 PF16457.5 EKX51882.1 - 3.9e-10 40.4 1.0 9.5e-10 39.1 0.4 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain Mcp5_PH PF12814.7 EKX51882.1 - 2.6e-07 30.8 0.2 5.9e-07 29.6 0.2 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology APS_kinase PF01583.20 EKX51882.1 - 0.039 13.8 0.2 0.065 13.1 0.2 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase TINF2_N PF14973.6 EKX51882.1 - 0.063 13.6 0.7 0.14 12.5 0.7 1.6 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus EF-hand_1 PF00036.32 EKX51882.1 - 0.081 12.5 0.0 0.37 10.4 0.0 2.2 2 0 0 2 2 2 0 EF hand PI-PLC-Y PF00387.19 EKX51883.1 - 0.0081 16.5 0.0 0.027 14.8 0.0 1.7 1 1 1 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain RNA_pol_3_Rpc31 PF11705.8 EKX51883.1 - 0.15 12.3 10.0 0.18 12.0 10.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RRN3 PF05327.11 EKX51883.1 - 2.1 6.8 4.2 1.7 7.1 4.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Clat_adaptor_s PF01217.20 EKX51884.1 - 3.7e-41 140.4 3.1 4.1e-41 140.2 3.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ion_trans PF00520.31 EKX51885.1 - 4.3e-156 517.4 37.5 1.5e-56 191.4 9.7 4.6 3 1 1 4 4 4 4 Ion transport protein EF-hand_6 PF13405.6 EKX51885.1 - 3e-12 45.4 0.6 0.00014 21.5 0.1 3.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EKX51885.1 - 1.6e-11 42.8 2.9 4.1e-05 22.8 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EKX51885.1 - 1.3e-10 41.5 0.7 3.7e-10 40.1 0.7 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX51885.1 - 2.3e-08 33.2 2.3 0.0046 16.4 0.1 2.9 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX51885.1 - 7.4e-08 32.1 0.9 5.3e-07 29.4 0.1 2.7 1 1 1 2 2 2 1 EF-hand domain pair PKD_channel PF08016.12 EKX51885.1 - 3.5e-06 26.0 51.5 0.00064 18.5 0.6 7.8 7 2 2 9 9 9 6 Polycystin cation channel GRP PF07172.11 EKX51885.1 - 0.0058 17.3 5.7 0.0058 17.3 5.7 2.6 2 0 0 2 2 2 1 Glycine rich protein family Dicty_REP PF05086.12 EKX51885.1 - 0.028 12.4 0.1 0.44 8.5 0.0 2.3 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein FAM176 PF14851.6 EKX51885.1 - 1.3 8.6 0.0 1.3 8.6 0.0 3.4 3 0 0 3 3 3 0 FAM176 family Skp1 PF01466.19 EKX51886.1 - 1.1e-17 63.9 0.5 1.9e-17 63.1 0.5 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EKX51886.1 - 7.6e-13 48.4 0.4 7.6e-13 48.4 0.4 2.4 2 1 0 2 2 2 1 Skp1 family, tetramerisation domain MS_channel PF00924.18 EKX51886.1 - 0.098 12.2 0.9 0.15 11.6 0.8 1.3 1 1 0 1 1 1 0 Mechanosensitive ion channel PUA_3 PF17785.1 EKX51886.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 PUA-like domain Mucin15 PF15672.5 EKX51887.1 - 0.39 10.1 6.3 0.56 9.7 6.3 1.2 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 2_5_RNA_ligase2 PF13563.6 EKX51888.1 - 2.1e-09 37.4 0.0 3.7e-09 36.7 0.0 1.4 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily CPDase PF07823.11 EKX51888.1 - 3.7e-07 30.0 0.1 0.0084 15.8 0.0 2.1 2 0 0 2 2 2 2 Cyclic phosphodiesterase-like protein LigT_PEase PF02834.16 EKX51888.1 - 4.2e-05 23.6 0.0 0.12 12.5 0.0 2.3 2 0 0 2 2 2 2 LigT like Phosphoesterase MmoB_DmpM PF02406.17 EKX51888.1 - 0.058 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 MmoB/DmpM family LRR_8 PF13855.6 EKX51889.1 - 6.1e-30 102.8 25.6 1.5e-09 37.5 2.1 4.2 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EKX51889.1 - 4.2e-22 77.9 26.4 3.1e-07 30.6 2.3 5.7 4 1 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX51889.1 - 4.7e-12 44.7 19.3 1 10.2 1.7 9.0 8 1 0 8 8 8 3 Leucine Rich Repeat LRR_9 PF14580.6 EKX51889.1 - 1.9e-06 27.5 11.9 0.034 13.7 1.1 3.2 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 EKX51889.1 - 6.4e-06 25.8 27.0 0.19 11.8 0.0 8.2 9 0 0 9 9 9 2 Leucine Rich repeat SLED PF12140.8 EKX51889.1 - 0.0045 17.5 0.3 1.1 9.8 0.0 2.5 1 1 1 2 2 2 1 SLED domain LRR_5 PF13306.6 EKX51889.1 - 0.012 15.5 0.2 0.068 13.1 0.7 2.0 3 0 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) LEDGF PF11467.8 EKX51889.1 - 0.088 12.4 0.6 0.49 10.0 0.0 2.6 2 2 1 3 3 3 0 Lens epithelium-derived growth factor (LEDGF) DUF2322 PF10084.9 EKX51889.1 - 0.096 12.7 0.0 0.65 10.1 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2322) 2H-phosphodiest PF08975.10 EKX51889.1 - 0.16 12.0 0.2 0.73 9.8 0.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1868) U-box PF04564.15 EKX51890.1 - 1.4e-08 34.7 0.0 1.5e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 EKX51890.1 - 0.016 15.4 0.0 0.021 15.0 0.0 1.2 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 EKX51890.1 - 0.051 13.4 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit MORN PF02493.20 EKX51891.1 - 1.3e-41 138.0 48.4 2.7e-07 30.1 4.6 6.3 6 0 0 6 6 6 6 MORN repeat DUF3048_C PF17479.2 EKX51891.1 - 0.0011 19.4 18.2 0.2 12.1 0.6 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3048) C-terminal domain PATR PF12951.7 EKX51891.1 - 0.15 12.2 0.8 0.4 10.8 0.0 2.2 2 0 0 2 2 2 0 Passenger-associated-transport-repeat Tudor_2 PF18104.1 EKX51891.1 - 1.7 8.4 11.9 6.4 6.6 0.0 4.9 6 0 0 6 6 6 0 Jumonji domain-containing protein 2A Tudor domain DUF5519 PF17648.1 EKX51893.1 - 0.053 13.4 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5519) GDA1_CD39 PF01150.17 EKX51894.1 - 6.9e-76 255.6 0.0 7.9e-76 255.4 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 EKX51894.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family DcpS_C PF11969.8 EKX51896.1 - 1.5e-20 73.7 0.3 2e-20 73.4 0.3 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EKX51896.1 - 1.5e-09 38.5 2.8 5e-09 36.8 2.8 1.7 1 1 0 1 1 1 1 HIT domain CwfJ_C_1 PF04677.15 EKX51896.1 - 0.023 14.5 1.5 0.041 13.7 1.5 1.5 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 TFIIS_M PF07500.14 EKX51897.1 - 3.4e-19 69.4 0.1 3.4e-19 69.4 0.1 2.8 4 0 0 4 4 4 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 EKX51897.1 - 2.1e-14 53.1 9.4 6.4e-14 51.5 9.4 1.8 1 1 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 EKX51897.1 - 2.6e-07 30.6 1.3 5.9e-07 29.4 1.3 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zinc_ribbon_4 PF13717.6 EKX51897.1 - 0.01 15.8 1.0 1.1 9.3 0.1 3.1 2 0 0 2 2 2 0 zinc-ribbon domain DUF1947 PF09183.10 EKX51897.1 - 0.25 11.7 1.2 0.69 10.2 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) Pkinase PF00069.25 EKX51899.1 - 5.8e-36 124.2 0.0 9.6e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PP2C PF00481.21 EKX51899.1 - 1.1e-28 100.6 0.3 1.7e-28 100.0 0.3 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Pkinase_Tyr PF07714.17 EKX51899.1 - 1.7e-27 96.3 0.0 7.1e-27 94.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX51899.1 - 6.6e-05 21.9 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX51899.1 - 0.015 15.2 1.2 0.03 14.2 0.2 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Asp_Arg_Hydrox PF05118.15 EKX51899.1 - 0.049 13.5 0.1 0.36 10.6 0.0 2.2 2 0 0 2 2 2 0 Aspartyl/Asparaginyl beta-hydroxylase HTH_AsnC-type PF13404.6 EKX51899.1 - 0.087 12.7 0.5 0.18 11.6 0.5 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Cid2 PF09774.9 EKX51900.1 - 0.078 13.4 0.3 0.24 11.8 0.1 2.0 2 0 0 2 2 2 0 Caffeine-induced death protein 2 Porin_3 PF01459.22 EKX51902.1 - 1.1e-29 103.7 1.0 1.3e-29 103.5 1.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Tctex-1 PF03645.13 EKX51902.1 - 0.006 16.8 0.4 0.066 13.4 0.1 2.2 2 0 0 2 2 2 1 Tctex-1 family GTP_CH_N PF12471.8 EKX51903.1 - 1.2e-81 273.1 0.0 1.6e-81 272.7 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 EKX51903.1 - 2e-16 60.0 0.0 3.2e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Tnp_P_element PF12017.8 EKX51904.1 - 0.0085 15.5 0.0 0.01 15.3 0.0 1.0 1 0 0 1 1 1 1 Transposase protein RCC1_2 PF13540.6 EKX51905.1 - 5.6e-29 99.3 51.2 1.9e-08 33.9 0.7 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EKX51905.1 - 0.00042 20.9 37.0 2.9 8.6 1.4 9.4 8 3 0 8 8 8 2 Regulator of chromosome condensation (RCC1) repeat PLDc PF00614.22 EKX51905.1 - 0.036 14.3 0.2 0.62 10.3 0.2 2.8 2 0 0 2 2 2 0 Phospholipase D Active site motif Pribosyltran PF00156.27 EKX51906.1 - 0.17 11.4 0.1 0.33 10.5 0.1 1.6 1 0 0 1 1 1 0 Phosphoribosyl transferase domain eIF3_subunit PF08597.10 EKX51907.1 - 0.025 14.5 6.3 0.026 14.5 2.8 2.2 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit SF1-HH PF16275.5 EKX51907.1 - 0.57 10.5 6.5 9.1 6.7 2.0 2.3 1 1 1 2 2 2 0 Splicing factor 1 helix-hairpin domain AKNA PF12443.8 EKX51907.1 - 2.3 8.9 9.4 0.15 12.7 2.3 2.5 2 0 0 2 2 2 0 AT-hook-containing transcription factor Lin-8 PF03353.15 EKX51907.1 - 3.9 6.9 10.4 0.12 11.9 3.1 1.9 1 1 1 2 2 2 0 Ras-mediated vulval-induction antagonist Metallophos PF00149.28 EKX51908.1 - 1.6e-37 130.0 0.0 2.1e-37 129.6 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EKX51908.1 - 0.07 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Ribosomal_S5_C PF03719.15 EKX51909.1 - 5.5e-25 86.6 0.0 8.9e-25 85.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 EKX51909.1 - 6.2e-25 87.0 2.2 1.3e-24 85.9 2.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain FoP_duplication PF13865.6 EKX51909.1 - 2.7 8.6 18.7 6.6 7.4 18.7 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 F-box-like PF12937.7 EKX51911.1 - 4.9e-05 23.1 0.2 0.00024 21.0 0.2 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EKX51911.1 - 7.2e-05 22.6 1.6 0.0002 21.1 1.6 1.8 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 EKX51911.1 - 0.038 14.9 5.2 18 6.4 0.1 5.1 5 1 0 5 5 5 0 WD domain, G-beta repeat RabGAP-TBC PF00566.18 EKX51912.1 - 4.2e-12 46.2 0.0 2.7e-07 30.5 0.1 3.3 3 0 0 3 3 3 3 Rab-GTPase-TBC domain RRM_1 PF00076.22 EKX51914.1 - 4.8e-85 279.4 4.3 5.4e-20 71.0 0.2 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EKX51914.1 - 7e-25 87.0 0.4 9.2e-23 80.2 0.6 2.6 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 EKX51914.1 - 5.6e-13 48.6 0.0 0.0029 17.2 0.0 4.4 2 2 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EKX51914.1 - 1.8e-06 27.9 1.8 0.34 11.0 0.0 4.5 4 0 0 4 4 4 2 RNA binding motif Nup35_RRM_2 PF14605.6 EKX51914.1 - 2.1e-06 27.6 0.9 2.7 8.1 0.0 4.2 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 EKX51914.1 - 1.1e-05 24.9 3.5 1.3 8.7 0.0 4.5 4 1 0 4 4 4 2 Histone lysine methyltransferase SET associated RRM_occluded PF16842.5 EKX51914.1 - 1.3e-05 25.0 0.0 0.66 9.9 0.0 4.5 5 1 0 5 5 5 2 Occluded RNA-recognition motif RRM_7 PF16367.5 EKX51914.1 - 2.3e-05 24.4 0.1 4.7 7.4 0.0 4.6 4 0 0 4 4 4 1 RNA recognition motif Limkain-b1 PF11608.8 EKX51914.1 - 0.00034 20.6 0.1 1.6 8.8 0.0 3.6 3 1 0 3 3 3 2 Limkain b1 BRAP2 PF07576.12 EKX51914.1 - 0.049 13.8 0.3 0.59 10.4 0.0 2.6 3 0 0 3 3 3 0 BRCA1-associated protein 2 OB_RNB PF08206.11 EKX51914.1 - 0.57 9.9 3.5 3.2 7.5 0.0 3.2 3 0 0 3 3 3 0 Ribonuclease B OB domain Polyketide_cyc2 PF10604.9 EKX51916.1 - 6.2e-11 42.7 0.0 7.7e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EKX51916.1 - 1.8e-10 41.1 0.0 2.6e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport COXG PF06240.13 EKX51916.1 - 0.044 13.5 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) Y1_Tnp PF01797.16 EKX51919.1 - 0.17 12.0 0.3 4 7.6 0.0 2.4 2 1 1 3 3 3 0 Transposase IS200 like TelA PF05816.11 EKX51919.1 - 0.39 9.7 5.7 0.045 12.8 1.1 1.6 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) SlyX PF04102.12 EKX51919.1 - 6.7 7.4 10.8 0.61 10.7 2.8 2.6 2 1 1 3 3 3 0 SlyX zf-U1 PF06220.12 EKX51920.1 - 0.039 13.7 0.0 2.6 7.9 0.0 2.6 2 0 0 2 2 2 0 U1 zinc finger Amnionless PF14828.6 EKX51921.1 - 0.0029 16.5 0.1 0.0037 16.2 0.1 1.1 1 0 0 1 1 1 1 Amnionless RCC1_2 PF13540.6 EKX51922.1 - 2.3e-33 113.3 24.8 2.1e-11 43.3 0.5 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EKX51922.1 - 1.3e-21 76.9 20.3 6.7e-07 29.8 0.1 6.6 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat TBP PF00352.21 EKX51922.1 - 0.00024 21.0 0.0 25 4.9 0.0 4.1 4 0 0 4 4 4 3 Transcription factor TFIID (or TATA-binding protein, TBP) DUF641 PF04859.12 EKX51923.1 - 0.052 13.9 4.1 0.075 13.4 2.7 1.7 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF4870 PF09685.10 EKX51925.1 - 0.0012 18.9 0.1 0.0091 16.1 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4870) Asp-Al_Ex PF06826.12 EKX51925.1 - 0.51 10.1 6.4 0.16 11.7 1.4 2.7 3 1 0 3 3 3 0 Predicted Permease Membrane Region Rep_fac-A_3 PF08661.11 EKX51926.1 - 8.6e-11 42.1 0.0 1.1e-10 41.8 0.0 1.3 1 1 0 1 1 1 1 Replication factor A protein 3 LCCL PF03815.19 EKX51927.1 - 4.1e-10 39.6 0.0 7.2e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 LCCL domain MAP17 PF15807.5 EKX51927.1 - 0.038 14.2 0.3 0.038 14.2 0.3 2.0 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 EVC2_like PF12297.8 EKX51927.1 - 0.91 8.1 3.0 3.1 6.4 0.5 2.0 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein SET PF00856.28 EKX51928.1 - 2e-16 60.8 0.1 3.6e-14 53.5 0.1 2.0 1 1 0 1 1 1 1 SET domain 2OG-FeII_Oxy_3 PF13640.6 EKX51929.1 - 3.9e-18 66.1 0.0 8.5e-18 65.0 0.0 1.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 EKX51929.1 - 8.8e-09 35.9 0.0 1.4e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Adaptin_N PF01602.20 EKX51930.1 - 1.2e-115 387.1 9.3 1.5e-115 386.8 9.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EKX51930.1 - 2.5e-44 151.1 0.0 5.7e-44 149.9 0.0 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 EKX51930.1 - 2.7e-19 69.4 1.0 6.6e-19 68.1 0.3 2.1 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 EKX51930.1 - 1.6e-18 66.9 1.3 8e-08 32.6 0.0 5.3 3 1 2 6 6 5 4 HEAT repeats Cnd1 PF12717.7 EKX51930.1 - 3.5e-09 36.9 16.6 0.00058 19.9 3.1 4.6 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EKX51930.1 - 0.00022 21.2 9.1 3 8.3 0.0 7.4 8 0 0 8 8 8 1 HEAT repeat Arm PF00514.23 EKX51930.1 - 0.0039 17.2 0.1 8.4 6.6 0.0 4.8 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EKX51930.1 - 0.019 15.5 2.1 0.86 10.2 0.1 3.9 3 1 1 4 4 4 0 HEAT-like repeat CLASP_N PF12348.8 EKX51930.1 - 0.03 13.9 3.9 3.2 7.2 0.4 3.3 3 1 0 4 4 4 0 CLASP N terminal RRF PF01765.19 EKX51930.1 - 0.045 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Ribosome recycling factor CM_1 PF07736.11 EKX51930.1 - 0.071 13.5 0.3 0.26 11.7 0.3 2.0 1 0 0 1 1 1 0 Chorismate mutase type I HEAT_PBS PF03130.16 EKX51930.1 - 0.32 11.8 5.4 23 6.0 0.0 4.9 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat U3snoRNP10 PF12397.8 EKX51930.1 - 6.4 7.2 7.1 2 8.8 1.3 2.8 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 EF-hand_6 PF13405.6 EKX51931.1 - 0.0014 18.4 0.0 0.0045 16.8 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 EKX51931.1 - 0.015 14.8 0.0 0.04 13.5 0.0 1.8 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 EKX51931.1 - 0.055 13.9 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair DSBA PF01323.20 EKX51932.1 - 3.6e-10 40.0 0.0 4.4e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain MFS_1 PF07690.16 EKX51933.1 - 0.0027 16.7 0.1 0.0027 16.7 0.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M13 PF01431.21 EKX51934.1 - 2.7e-64 216.6 0.5 1.2e-62 211.2 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M13 Peptidase_M13_N PF05649.13 EKX51934.1 - 2.6e-29 103.1 0.4 3.8e-29 102.5 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M13 Carb_anhydrase PF00194.21 EKX51935.1 - 1.7e-31 109.7 0.1 1.8e-31 109.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Ank_2 PF12796.7 EKX51936.1 - 2.9e-09 37.4 0.0 1.1e-08 35.6 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX51936.1 - 1.5e-08 35.0 0.0 1.2e-05 25.8 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX51936.1 - 3e-06 27.4 0.0 0.00061 20.1 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EKX51936.1 - 5.2e-06 26.4 0.0 0.00025 21.2 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EKX51936.1 - 5.8e-06 26.5 0.0 1.4e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DUF4293 PF14126.6 EKX51936.1 - 0.12 12.7 2.0 0.38 11.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) HemY_N PF07219.13 EKX51936.1 - 0.24 11.6 0.0 0.24 11.6 0.0 2.6 4 1 1 5 5 5 0 HemY protein N-terminus WBP-1 PF11669.8 EKX51936.1 - 0.74 10.5 7.8 4 8.1 0.4 2.7 3 0 0 3 3 3 0 WW domain-binding protein 1 SelK_SelG PF10961.8 EKX51936.1 - 5.3 7.7 7.4 0.31 11.7 0.3 2.4 2 1 0 2 2 2 0 Selenoprotein SelK_SelG Ank_4 PF13637.6 EKX51937.1 - 8.3e-05 23.1 0.0 0.0024 18.4 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX51937.1 - 0.00012 22.6 0.0 0.00044 20.8 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX51937.1 - 0.0025 18.2 4.5 0.042 14.3 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EKX51937.1 - 0.006 17.0 3.4 0.07 13.7 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EKX51937.1 - 0.0068 16.7 0.0 0.021 15.1 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Asp5 PF17000.5 EKX51937.1 - 0.069 13.3 0.8 0.069 13.3 0.8 2.0 2 0 0 2 2 2 0 Accessory secretory protein Sec, Asp5 Dexa_ind PF15198.6 EKX51937.1 - 0.21 11.7 0.2 0.21 11.7 0.2 1.8 2 0 0 2 2 2 0 Dexamethasone-induced DUF3671 PF12420.8 EKX51937.1 - 3.5 7.7 5.4 1.1 9.4 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function Pho86 PF11124.8 EKX51937.1 - 4.9 6.5 9.3 0.86 9.0 0.2 2.0 1 1 1 2 2 2 0 Inorganic phosphate transporter Pho86 TssO PF17561.2 EKX51937.1 - 5.1 7.2 4.7 5.7 7.0 0.0 2.5 3 0 0 3 3 3 0 Type VI secretion system, TssO DUF4094 PF13334.6 EKX51937.1 - 9.5 6.7 8.4 1.3 9.5 2.0 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF4094) DTW PF03942.15 EKX51938.1 - 5.1e-22 78.6 0.0 8.8e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 DTW domain zf-B_box PF00643.24 EKX51938.1 - 0.31 11.2 4.0 0.52 10.5 4.0 1.4 1 0 0 1 1 1 0 B-box zinc finger Ank_2 PF12796.7 EKX51939.1 - 9.2e-21 74.2 0.0 4.2e-14 52.9 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX51939.1 - 2.8e-20 72.4 0.3 1.2e-08 35.4 0.0 3.7 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX51939.1 - 1.4e-16 58.8 0.9 0.00061 20.1 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 EKX51939.1 - 1.6e-15 56.7 0.9 0.00065 20.0 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EKX51939.1 - 4.4e-12 46.0 3.0 0.003 17.9 0.2 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) CCDC53 PF10152.9 EKX51942.1 - 0.033 14.6 0.1 0.057 13.8 0.1 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex SPRY PF00622.28 EKX51943.1 - 6.7e-06 26.2 0.1 1.3e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 SPRY domain NOA36 PF06524.12 EKX51943.1 - 0.016 14.5 13.6 0.028 13.8 13.6 1.3 1 0 0 1 1 1 0 NOA36 protein RPN2_C PF18004.1 EKX51943.1 - 1.3 9.0 6.5 3.4 7.6 6.5 1.7 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain RNA_pol_3_Rpc31 PF11705.8 EKX51943.1 - 2.5 8.3 20.5 0.76 10.0 17.2 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Ank_2 PF12796.7 EKX51945.1 - 1.8e-15 57.3 0.0 1.9e-14 54.0 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX51945.1 - 2e-13 50.1 0.0 8.7e-07 29.1 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EKX51945.1 - 1.1e-12 48.2 0.0 3.1e-05 24.4 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX51945.1 - 1.5e-12 46.5 0.1 3.9e-05 23.7 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EKX51945.1 - 3.4e-09 36.8 0.1 0.0016 18.7 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF5535 PF17687.1 EKX51945.1 - 0.064 13.4 0.0 0.13 12.4 0.0 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5535) WD40 PF00400.32 EKX51946.1 - 1.1e-23 83.0 16.7 3.8e-06 27.5 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX51946.1 - 9.5e-17 61.1 9.1 8.8e-06 25.9 0.5 4.7 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EKX51946.1 - 3.1e-06 27.2 0.5 0.16 11.9 0.0 3.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EKX51946.1 - 0.00018 20.6 3.8 0.049 12.6 0.0 3.7 2 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Arf PF00025.21 EKX51946.1 - 0.14 11.6 0.1 0.55 9.7 0.1 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family IQ PF00612.27 EKX51947.1 - 3.3e-05 23.3 6.1 0.0049 16.5 1.9 3.2 2 0 0 2 2 2 2 IQ calmodulin-binding motif NACHT PF05729.12 EKX51947.1 - 0.0002 21.4 0.3 0.27 11.1 0.0 2.6 2 0 0 2 2 2 2 NACHT domain EF-hand_6 PF13405.6 EKX51947.1 - 0.00038 20.2 0.4 0.3 11.1 0.2 4.3 4 0 0 4 4 4 1 EF-hand domain AAA_16 PF13191.6 EKX51947.1 - 0.0055 17.1 6.2 0.0067 16.8 0.6 3.5 2 2 0 2 2 2 1 AAA ATPase domain Myc_N PF01056.18 EKX51947.1 - 0.012 15.5 0.7 0.03 14.2 0.7 1.6 1 0 0 1 1 1 0 Myc amino-terminal region APAF1_C PF17908.1 EKX51947.1 - 0.018 15.1 0.0 0.083 12.9 0.0 2.2 1 0 0 1 1 1 0 APAF-1 helical domain EF-hand_1 PF00036.32 EKX51947.1 - 0.019 14.5 1.1 2 8.2 0.0 3.5 3 0 0 3 3 3 0 EF hand AAA_29 PF13555.6 EKX51947.1 - 0.033 13.9 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EKX51947.1 - 0.1 12.9 0.2 1.1 9.5 0.0 2.7 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 EKX51947.1 - 0.24 11.9 0.9 1.4 9.4 0.0 2.7 3 0 0 3 3 3 0 ABC transporter EF-hand_7 PF13499.6 EKX51947.1 - 0.78 10.2 6.0 0.67 10.5 0.4 3.9 3 1 0 3 3 3 0 EF-hand domain pair ATP-synt PF00231.19 EKX51948.1 - 1.1e-90 304.1 0.7 1.3e-90 303.9 0.7 1.0 1 0 0 1 1 1 1 ATP synthase Methyltransf_31 PF13847.6 EKX51948.1 - 0.1 12.4 0.0 0.43 10.4 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain CK_II_beta PF01214.18 EKX51949.1 - 2.3e-72 242.6 0.0 2.7e-72 242.4 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit ABC_membrane_2 PF06472.15 EKX51950.1 - 2.4e-86 289.5 1.4 3.1e-86 289.1 1.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EKX51950.1 - 3.9e-18 66.3 0.0 9.9e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 EKX51950.1 - 9.2e-05 23.0 0.1 0.0018 18.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EKX51950.1 - 0.00036 20.4 0.0 0.0017 18.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EKX51950.1 - 0.0011 18.5 0.0 0.12 11.8 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain Adeno_IVa2 PF02456.15 EKX51950.1 - 0.0042 15.9 0.1 0.0075 15.1 0.1 1.3 1 0 0 1 1 1 1 Adenovirus IVa2 protein AAA_29 PF13555.6 EKX51950.1 - 0.0045 16.7 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.15 EKX51950.1 - 0.017 15.0 0.1 0.065 13.2 0.0 2.0 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_27 PF13514.6 EKX51950.1 - 0.032 13.8 0.0 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EKX51950.1 - 0.049 13.3 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF4293 PF14126.6 EKX51950.1 - 0.082 13.2 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) AAA_18 PF13238.6 EKX51950.1 - 0.1 13.1 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF1126 PF06565.12 EKX51951.1 - 6.1e-94 308.9 4.9 7.9e-35 118.9 0.3 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain bZIP_1 PF00170.21 EKX51952.1 - 0.00048 20.2 3.5 0.00048 20.2 3.5 3.0 3 0 0 3 3 3 1 bZIP transcription factor ADIP PF11559.8 EKX51952.1 - 0.0011 19.0 21.3 0.012 15.7 6.5 2.8 1 1 2 3 3 3 2 Afadin- and alpha -actinin-Binding DivIC PF04977.15 EKX51952.1 - 0.0013 18.4 17.4 0.0024 17.6 1.8 3.0 2 1 1 3 3 3 2 Septum formation initiator HAP1_N PF04849.13 EKX51952.1 - 0.002 17.4 20.5 0.012 14.9 4.6 2.1 1 1 1 2 2 2 2 HAP1 N-terminal conserved region Filament PF00038.21 EKX51952.1 - 0.0035 17.0 18.4 0.0095 15.5 10.4 2.1 1 1 1 2 2 2 1 Intermediate filament protein SHE3 PF17078.5 EKX51952.1 - 0.0056 16.4 14.1 0.034 13.9 4.4 2.3 1 1 2 3 3 3 2 SWI5-dependent HO expression protein 3 ZapB PF06005.12 EKX51952.1 - 0.01 16.2 18.6 0.069 13.6 9.2 2.6 1 1 1 2 2 2 0 Cell division protein ZapB TSC22 PF01166.18 EKX51952.1 - 0.014 15.7 5.8 0.072 13.4 1.4 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family JIP_LZII PF16471.5 EKX51952.1 - 0.015 15.5 3.4 0.015 15.5 3.4 3.0 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II bZIP_2 PF07716.15 EKX51952.1 - 0.017 15.2 1.6 0.017 15.2 1.6 2.9 3 0 0 3 3 2 0 Basic region leucine zipper APG6_N PF17675.1 EKX51952.1 - 0.022 15.3 22.1 0.33 11.5 8.3 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4407 PF14362.6 EKX51952.1 - 0.026 13.9 11.7 0.033 13.5 11.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MSP1_C PF07462.11 EKX51952.1 - 0.027 13.2 7.2 0.4 9.3 3.9 2.0 1 1 1 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus CENP-F_leu_zip PF10473.9 EKX51952.1 - 0.038 14.0 21.8 0.037 14.0 13.1 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PKcGMP_CC PF16808.5 EKX51952.1 - 0.043 13.7 3.1 0.043 13.7 3.1 3.1 4 0 0 4 4 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase APC_N_CC PF16689.5 EKX51952.1 - 0.045 13.8 5.8 0.9 9.7 1.4 2.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain DUF2730 PF10805.8 EKX51952.1 - 0.046 13.8 11.3 0.89 9.7 4.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) HALZ PF02183.18 EKX51952.1 - 0.068 13.4 1.2 0.068 13.4 1.2 2.7 3 0 0 3 3 2 0 Homeobox associated leucine zipper Shugoshin_N PF07558.11 EKX51952.1 - 0.084 12.8 0.7 0.084 12.8 0.7 2.4 3 0 0 3 3 2 0 Shugoshin N-terminal coiled-coil region ASD2 PF08687.11 EKX51952.1 - 0.085 12.4 18.4 0.32 10.5 7.9 2.0 1 1 1 2 2 2 0 Apx/Shroom domain ASD2 Tup_N PF08581.10 EKX51952.1 - 0.095 13.0 11.5 0.91 9.9 0.8 3.5 1 1 2 3 3 3 0 Tup N-terminal TMF_TATA_bd PF12325.8 EKX51952.1 - 0.11 12.8 21.3 0.13 12.5 2.8 2.9 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding YkyA PF10368.9 EKX51952.1 - 0.11 12.1 15.9 0.13 12.0 6.3 2.1 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein DUF5082 PF16888.5 EKX51952.1 - 0.14 12.4 13.0 0.3 11.4 9.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) MPS2 PF17060.5 EKX51952.1 - 0.16 11.2 14.8 0.36 10.0 14.7 1.5 1 1 0 1 1 1 0 Monopolar spindle protein 2 DUF724 PF05266.14 EKX51952.1 - 0.21 11.4 17.7 0.086 12.7 3.5 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF724) DUF4337 PF14235.6 EKX51952.1 - 0.21 11.7 13.5 1.7 8.8 6.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Fez1 PF06818.15 EKX51952.1 - 0.31 11.5 20.6 4 7.8 20.6 2.0 1 1 0 1 1 1 0 Fez1 GAS PF13851.6 EKX51952.1 - 0.32 10.3 20.9 1.1 8.5 2.8 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 EKX51952.1 - 0.33 11.6 12.3 0.067 13.8 4.2 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Fungal_TACC PF12709.7 EKX51952.1 - 0.34 11.4 11.5 0.94 10.0 1.7 2.8 1 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins ERM PF00769.19 EKX51952.1 - 0.38 10.5 21.6 0.64 9.8 20.5 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Atg14 PF10186.9 EKX51952.1 - 0.4 9.7 18.7 0.9 8.6 18.7 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Lebercilin PF15619.6 EKX51952.1 - 0.47 10.1 22.2 2.2 7.9 21.1 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HIP1_clath_bdg PF16515.5 EKX51952.1 - 0.48 11.1 23.1 1.3 9.7 7.5 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 BRE1 PF08647.11 EKX51952.1 - 0.73 9.9 17.5 4.9 7.3 4.6 2.9 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase UPF0227 PF05728.12 EKX51952.1 - 0.81 9.6 3.2 0.53 10.2 0.8 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Ax_dynein_light PF10211.9 EKX51952.1 - 0.82 9.6 18.6 0.049 13.6 4.9 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain Exonuc_VII_L PF02601.15 EKX51952.1 - 0.9 9.1 11.5 1.3 8.5 11.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit FlaC_arch PF05377.11 EKX51952.1 - 0.9 10.0 11.9 0.19 12.1 1.2 3.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 EKX51952.1 - 0.9 9.6 19.2 3.9 7.5 10.0 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus SpecificRecomb PF10136.9 EKX51952.1 - 0.92 7.7 10.0 1.1 7.5 10.0 1.1 1 0 0 1 1 1 0 Site-specific recombinase DUF4472 PF14739.6 EKX51952.1 - 0.98 10.2 16.5 0.46 11.2 2.7 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) TMF_DNA_bd PF12329.8 EKX51952.1 - 0.98 9.5 18.7 1.2 9.2 5.4 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Cnn_1N PF07989.11 EKX51952.1 - 1.2 9.3 13.7 0.19 11.9 2.0 2.9 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 DUF641 PF04859.12 EKX51952.1 - 1.3 9.3 17.2 16 5.8 5.4 2.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF3450 PF11932.8 EKX51952.1 - 1.5 8.1 19.4 1.7 7.9 6.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF16 PF01519.16 EKX51952.1 - 2 8.9 15.8 3.3 8.2 6.1 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 Ly49 PF08391.10 EKX51952.1 - 2.2 8.7 13.2 2.9 8.3 4.2 2.1 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region LPP PF04728.13 EKX51952.1 - 2.2 8.7 7.8 1.4 9.4 3.0 3.1 2 1 0 2 2 2 0 Lipoprotein leucine-zipper FliD_N PF02465.18 EKX51952.1 - 2.3 9.0 10.0 0.59 10.9 4.4 2.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus USP8_interact PF08941.10 EKX51952.1 - 2.5 7.9 10.1 0.95 9.3 2.5 2.2 1 1 0 2 2 2 0 USP8 interacting Spc7 PF08317.11 EKX51952.1 - 2.7 6.8 21.8 1.6 7.5 6.4 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4140 PF13600.6 EKX51952.1 - 3.4 8.2 17.1 4.7 7.7 1.9 3.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) V_ATPase_I PF01496.19 EKX51952.1 - 3.7 5.3 14.7 0.65 7.8 6.0 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family SLX9 PF15341.6 EKX51952.1 - 4 7.8 14.4 0.4 11.1 1.6 2.1 1 1 1 2 2 2 0 Ribosome biogenesis protein SLX9 zf-C4H2 PF10146.9 EKX51952.1 - 4.3 7.6 12.7 3.8 7.8 0.5 2.4 2 1 0 2 2 2 0 Zinc finger-containing protein Nsp1_C PF05064.13 EKX51952.1 - 4.4 7.1 12.3 0.32 10.8 1.0 2.7 1 1 2 3 3 3 0 Nsp1-like C-terminal region PCRF PF03462.18 EKX51952.1 - 4.5 7.1 15.3 0.89 9.4 7.8 2.0 1 1 1 2 2 2 0 PCRF domain FUSC PF04632.12 EKX51952.1 - 4.6 5.7 5.0 5.5 5.4 5.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family GIT_CC PF16559.5 EKX51952.1 - 4.7 7.2 10.9 0.25 11.2 1.0 3.2 3 1 1 4 4 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Csm1_N PF18504.1 EKX51952.1 - 4.9 7.6 17.3 2.3 8.6 2.2 3.4 1 1 1 3 3 3 0 Csm1 N-terminal domain Swi5 PF07061.11 EKX51952.1 - 5.5 7.2 12.5 18 5.5 0.8 3.2 1 1 1 2 2 2 0 Swi5 HAUS6_N PF14661.6 EKX51952.1 - 5.5 6.5 17.5 0.33 10.5 4.9 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus TMPIT PF07851.13 EKX51952.1 - 5.7 6.1 15.9 1.6 7.9 5.8 2.1 1 1 1 2 2 2 0 TMPIT-like protein Uso1_p115_C PF04871.13 EKX51952.1 - 5.9 7.3 19.4 58 4.1 19.4 2.1 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region MCU PF04678.13 EKX51952.1 - 7.5 6.6 14.2 4.1 7.5 5.3 2.1 1 1 1 2 2 2 0 Mitochondrial calcium uniporter DUF5595 PF18077.1 EKX51952.1 - 9.3 6.4 10.2 0.28 11.3 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) TPR_1 PF00515.28 EKX51953.1 - 9.1e-10 37.9 11.5 2.2e-05 24.1 0.3 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX51953.1 - 1.4e-08 34.2 12.3 0.00027 20.8 0.1 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX51953.1 - 0.00012 21.7 1.5 0.37 10.5 0.0 3.1 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.6 EKX51953.1 - 0.00018 21.7 8.6 0.32 11.3 2.4 4.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX51953.1 - 0.00041 20.4 1.0 0.0015 18.7 1.0 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX51953.1 - 0.001 19.7 5.5 1.9 9.5 0.1 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX51953.1 - 0.0079 16.7 8.4 2.2 8.8 0.2 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX51953.1 - 0.013 16.1 1.0 7.7 7.4 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 EKX51953.1 - 0.09 13.2 4.4 2.1 8.9 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EKX51953.1 - 0.15 12.2 3.3 4.1 7.6 0.0 4.2 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX51953.1 - 0.37 11.1 12.1 7.7 7.0 0.1 4.7 6 0 0 6 6 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX51953.1 - 0.5 10.5 2.4 1 9.5 0.0 2.7 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.20 EKX51953.1 - 0.55 10.6 2.5 2 8.9 0.1 3.1 3 0 0 3 3 3 0 PPR repeat DUF4787 PF16029.5 EKX51953.1 - 0.82 9.8 3.6 2.3 8.4 3.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4787) DUF5339 PF17274.2 EKX51953.1 - 2.4 9.0 7.0 0.51 11.2 0.5 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5339) FKBP_C PF00254.28 EKX51954.1 - 1.4e-15 57.4 0.0 1.5e-15 57.2 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_6 PF13405.6 EKX51955.1 - 1.5e-07 30.8 2.3 0.48 10.5 0.0 5.0 5 0 0 5 5 5 2 EF-hand domain EF-hand_7 PF13499.6 EKX51955.1 - 1.1e-06 29.0 8.5 7.2e-05 23.2 1.2 4.4 3 2 1 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX51955.1 - 5.6e-06 25.5 1.2 0.057 13.0 0.0 4.3 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 EKX51955.1 - 3.5e-05 23.5 0.1 0.25 11.2 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_13 PF17958.1 EKX51955.1 - 0.006 16.4 0.0 0.018 14.8 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 EKX51955.1 - 0.048 13.2 0.0 3.4 7.3 0.0 2.7 2 0 0 2 2 2 0 EF hand SpoU_methylase PF00588.19 EKX51956.1 - 1.6e-11 44.5 0.0 3.6e-11 43.4 0.0 1.7 2 0 0 2 2 2 1 SpoU rRNA Methylase family Fe-ADH PF00465.19 EKX51958.1 - 2.1e-108 362.4 0.1 4.1e-108 361.5 0.1 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Aldedh PF00171.22 EKX51958.1 - 1.8e-26 92.7 3.7 5.5e-25 87.8 3.7 2.1 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Fe-ADH_2 PF13685.6 EKX51958.1 - 3.8e-14 53.0 5.6 3e-06 27.2 1.8 3.1 3 0 0 3 3 3 2 Iron-containing alcohol dehydrogenase Glutaredoxin PF00462.24 EKX51958.1 - 0.055 13.7 0.0 2.8 8.2 0.0 3.0 3 0 0 3 3 3 0 Glutaredoxin pRN1_helical PF13010.6 EKX51958.1 - 0.12 12.4 0.4 0.34 10.9 0.4 1.8 1 0 0 1 1 1 0 Primase helical domain Fe-ADH PF00465.19 EKX51959.1 - 1.7e-108 362.7 0.1 3.4e-108 361.7 0.1 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Aldedh PF00171.22 EKX51959.1 - 5.9e-26 91.0 3.7 1.2e-24 86.7 3.7 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Fe-ADH_2 PF13685.6 EKX51959.1 - 5.2e-14 52.6 5.4 3.1e-06 27.1 1.8 3.1 3 0 0 3 3 3 2 Iron-containing alcohol dehydrogenase Glutaredoxin PF00462.24 EKX51959.1 - 0.059 13.6 0.0 2.9 8.2 0.0 3.0 3 0 0 3 3 3 0 Glutaredoxin Tubulin_C PF03953.17 EKX51959.1 - 0.13 12.4 0.1 0.75 10.0 0.1 2.2 2 0 0 2 2 2 0 Tubulin C-terminal domain pRN1_helical PF13010.6 EKX51959.1 - 0.19 11.7 0.4 0.53 10.3 0.4 1.8 1 0 0 1 1 1 0 Primase helical domain NHL PF01436.21 EKX51960.1 - 9e-32 107.5 12.8 1.9e-10 40.2 0.3 4.2 4 0 0 4 4 4 4 NHL repeat SGL PF08450.12 EKX51960.1 - 3.3e-11 43.2 0.3 0.0013 18.4 0.0 3.1 1 1 1 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region DUF5128 PF17170.4 EKX51960.1 - 8.2e-11 41.6 1.9 0.0017 17.5 0.0 3.7 1 1 3 4 4 4 3 6-bladed beta-propeller SBBP PF06739.11 EKX51960.1 - 6.3e-06 26.1 3.2 0.19 11.7 0.6 3.3 3 0 0 3 3 3 2 Beta-propeller repeat Phytase-like PF13449.6 EKX51960.1 - 0.00031 20.8 0.1 0.38 10.7 0.0 2.4 2 1 0 3 3 3 2 Esterase-like activity of phytase Ldl_recept_b PF00058.17 EKX51960.1 - 0.12 12.9 0.1 25 5.5 0.0 3.6 3 1 0 3 3 3 0 Low-density lipoprotein receptor repeat class B ALMT PF11744.8 EKX51961.1 - 2.6 6.8 7.3 4.5 6.0 7.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter NUDIX PF00293.28 EKX51962.1 - 3.9e-14 52.8 0.0 4.4e-14 52.6 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain Guanylate_cyc PF00211.20 EKX51963.1 - 3.6e-28 98.4 0.0 4e-28 98.3 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Rhodanese PF00581.20 EKX51964.1 - 1.3e-12 48.1 0.0 1.5e-12 48.0 0.0 1.0 1 0 0 1 1 1 1 Rhodanese-like domain SAG PF04092.13 EKX51964.1 - 0.011 16.5 0.0 0.014 16.1 0.0 1.3 1 1 0 1 1 1 0 SRS domain Ank_5 PF13857.6 EKX51965.1 - 2.5e-17 62.7 0.5 2.5e-09 37.2 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX51965.1 - 2.3e-13 49.0 0.3 3.9e-06 26.8 0.1 2.3 2 1 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EKX51965.1 - 1.1e-10 41.5 1.8 0.00031 21.0 0.1 2.2 2 1 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EKX51965.1 - 1.9e-10 41.0 0.0 2.7e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX51965.1 - 2.4e-08 34.5 0.1 5.1e-08 33.4 0.1 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) DUF2520 PF10728.9 EKX51965.1 - 0.048 13.4 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) RWP-RK PF02042.15 EKX51966.1 - 6.7e-09 35.6 0.1 1.5e-08 34.4 0.1 1.6 1 0 0 1 1 1 1 RWP-RK domain ssDNA_TraI_N PF18272.1 EKX51966.1 - 0.011 15.7 0.1 0.046 13.7 0.1 2.0 2 0 0 2 2 2 0 single-stranded DNA binding TraI N-terminal subdomain DUF719 PF05334.13 EKX51966.1 - 0.047 13.9 0.1 0.082 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF719) LRR_4 PF12799.7 EKX51967.1 - 2.5e-16 59.5 5.5 2.7e-06 27.6 0.0 3.4 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX51967.1 - 2.8e-10 39.8 5.9 0.00018 21.2 0.1 3.5 2 2 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 EKX51967.1 - 7.1e-08 32.2 0.0 0.001 18.6 0.0 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 EKX51967.1 - 0.0081 16.6 3.7 1.3e+02 3.8 0.0 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 EKX51967.1 - 0.02 14.9 3.8 12 6.2 0.0 4.7 4 1 1 5 5 5 0 Leucine Rich repeat EPF PF17181.4 EKX51968.1 - 0.05 13.6 0.1 2.1 8.4 0.1 2.2 2 0 0 2 2 2 0 Epidermal patterning factor proteins E3_UFM1_ligase PF09743.9 EKX51969.1 - 4.2e-64 216.8 4.4 1.5e-33 116.6 1.7 2.4 1 1 1 2 2 2 2 E3 UFM1-protein ligase 1 Ank_2 PF12796.7 EKX51970.1 - 0.00016 22.2 0.0 0.00051 20.6 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX51970.1 - 0.00038 20.9 0.0 0.0047 17.5 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX51970.1 - 0.0032 17.8 0.0 0.023 15.2 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EKX51970.1 - 0.0038 17.6 0.0 0.021 15.3 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeat MurB_C PF02873.16 EKX51970.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain DUF5555 PF17710.1 EKX51973.1 - 0.017 14.6 1.0 0.021 14.3 1.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5555) UvrD-helicase PF00580.21 EKX51974.1 - 4.8e-52 177.4 0.4 2e-51 175.4 0.4 2.0 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 EKX51974.1 - 5e-30 104.8 0.0 1.2e-29 103.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C PF13361.6 EKX51974.1 - 1.1e-14 54.6 3.8 1.2e-08 34.8 0.0 3.7 3 1 1 4 4 4 3 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 EKX51974.1 - 4.1e-07 29.9 0.6 0.0041 16.9 0.0 2.7 2 1 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 EKX51974.1 - 9.4e-05 22.3 0.4 0.85 9.3 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 EKX51974.1 - 0.00029 20.6 0.0 0.0007 19.4 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain ResIII PF04851.15 EKX51974.1 - 0.11 12.5 0.2 0.94 9.5 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit K-box PF01486.17 EKX51975.1 - 0.025 14.7 1.2 0.047 13.9 1.2 1.4 1 0 0 1 1 1 0 K-box region LCD1 PF09798.9 EKX51975.1 - 0.099 11.1 0.2 0.14 10.7 0.2 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein FAM184 PF15665.5 EKX51975.1 - 0.22 11.3 4.4 1.3 8.8 1.5 2.1 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B Alpha_kinase PF02816.18 EKX51977.1 - 1.8e-53 181.4 0.6 2.3e-53 181.1 0.6 1.1 1 0 0 1 1 1 1 Alpha-kinase family DASH_Dad3 PF08656.10 EKX51979.1 - 0.00018 21.5 0.0 0.00023 21.2 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 GAS PF13851.6 EKX51979.1 - 0.0022 17.4 0.0 0.0027 17.1 0.0 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 EKX51979.1 - 0.0052 16.6 1.1 0.0066 16.3 1.1 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH TraB PF01963.17 EKX51980.1 - 1.5e-12 48.0 0.0 9.3e-06 25.7 0.0 2.6 1 1 1 2 2 2 2 TraB family DUF4363 PF14276.6 EKX51981.1 - 0.043 13.9 0.4 0.043 13.9 0.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4363) DUF1771 PF08590.10 EKX51981.1 - 0.069 13.5 0.3 0.069 13.5 0.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1771) NDK PF00334.19 EKX51984.1 - 1.2e-77 258.4 0.0 6.3e-42 142.8 0.0 2.1 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DUF1126 PF06565.12 EKX51984.1 - 7.4e-06 25.7 0.4 1.6e-05 24.7 0.4 1.6 1 0 0 1 1 1 1 DUF1126 PH-like domain PFK PF00365.20 EKX51985.1 - 1.6e-66 224.6 0.0 2.5e-66 223.9 0.0 1.2 1 0 0 1 1 1 1 Phosphofructokinase DAGK_cat PF00781.24 EKX51985.1 - 0.013 15.1 0.1 0.028 14.0 0.1 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain peroxidase PF00141.23 EKX51986.1 - 1.5e-41 142.6 0.0 1.8e-41 142.3 0.0 1.0 1 0 0 1 1 1 1 Peroxidase Actin PF00022.19 EKX51987.1 - 4.7e-128 427.3 0.0 6e-128 426.9 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EKX51987.1 - 0.087 11.6 0.0 2.6 6.8 0.0 2.3 2 0 0 2 2 2 0 MreB/Mbl protein TMF_TATA_bd PF12325.8 EKX51988.1 - 0.013 15.7 6.8 0.013 15.7 6.8 1.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 EKX51988.1 - 0.12 12.2 6.0 0.22 11.3 6.0 1.5 1 0 0 1 1 1 0 Septum formation initiator HAUS6_N PF14661.6 EKX51988.1 - 0.19 11.3 4.3 0.22 11.1 4.3 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus PAF-AH_p_II PF03403.13 EKX51989.1 - 4.7e-55 186.6 0.0 9.5e-55 185.6 0.0 1.4 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EKX51989.1 - 1.7e-07 30.4 0.5 2.4e-06 26.6 0.5 2.1 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EKX51989.1 - 0.00016 20.8 0.0 0.018 14.1 0.0 2.3 2 0 0 2 2 2 2 Chlorophyllase DLH PF01738.18 EKX51989.1 - 0.0022 17.6 0.0 2.2 7.8 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EKX51989.1 - 0.0081 15.8 0.0 0.67 9.5 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EKX51989.1 - 0.032 13.5 0.6 0.22 10.8 0.1 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EKX51989.1 - 0.071 13.7 0.0 0.21 12.2 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF1100 PF06500.11 EKX51989.1 - 0.097 11.5 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Sdh5 PF03937.16 EKX51990.1 - 1.8e-11 43.8 1.8 4.8e-11 42.5 0.7 2.0 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase Glutaredoxin PF00462.24 EKX51991.1 - 2.4e-39 133.4 0.0 1.5e-16 60.4 0.0 3.3 3 0 0 3 3 3 3 Glutaredoxin Thioredoxin PF00085.20 EKX51991.1 - 5.1e-11 42.5 0.1 1.2e-10 41.3 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin SH3BGR PF04908.15 EKX51991.1 - 4.4e-08 33.2 0.0 0.0067 16.6 0.0 2.5 2 0 0 2 2 2 2 SH3-binding, glutamic acid-rich protein GST_N_3 PF13417.6 EKX51991.1 - 2.9e-05 24.4 0.0 0.37 11.3 0.0 2.7 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain Thioredoxin_3 PF13192.6 EKX51991.1 - 0.00053 20.0 0.1 0.0014 18.6 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin domain HyaE PF07449.11 EKX51991.1 - 0.00061 19.7 0.1 0.0042 17.0 0.0 2.5 4 1 1 5 5 5 1 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 EKX51991.1 - 0.0015 19.0 0.0 0.0042 17.5 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain ZinT PF09223.11 EKX51991.1 - 0.017 15.0 0.0 7.2 6.5 0.0 2.2 2 0 0 2 2 2 0 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment DUF2535 PF10751.9 EKX51991.1 - 0.036 14.6 0.1 16 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2535) Thioredoxin_8 PF13905.6 EKX51991.1 - 0.049 14.0 0.0 0.3 11.4 0.0 2.2 1 1 0 1 1 1 0 Thioredoxin-like OST3_OST6 PF04756.13 EKX51991.1 - 0.058 12.7 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Gag_p6 PF08705.11 EKX51991.1 - 0.061 13.6 0.0 21 5.4 0.0 2.5 2 0 0 2 2 2 0 Gag protein p6 Sigma54_activ_2 PF14532.6 EKX51991.1 - 0.12 12.5 0.2 21 5.2 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain Chlorophyllase2 PF12740.7 EKX51991.1 - 0.15 10.9 0.0 16 4.3 0.0 2.2 2 0 0 2 2 2 0 Chlorophyllase enzyme His_Phos_2 PF00328.22 EKX51993.1 - 5.8e-86 289.2 0.8 8e-86 288.8 0.8 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 EKX51993.1 - 5.8e-29 100.1 0.1 6.4e-28 96.7 0.1 2.5 1 1 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain His_Phos_1 PF00300.22 EKX51993.1 - 0.082 12.6 0.1 0.87 9.2 0.0 2.7 2 1 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) hDGE_amylase PF14701.6 EKX51993.1 - 0.091 11.8 0.5 0.22 10.6 0.5 1.6 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain SPX PF03105.19 EKX51993.1 - 0.15 12.0 3.2 0.062 13.2 0.3 1.8 2 0 0 2 2 2 0 SPX domain ATP-grasp_3 PF02655.14 EKX51993.1 - 0.15 12.1 0.0 0.61 10.1 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain TIP120 PF08623.10 EKX51993.1 - 0.19 11.5 1.2 3.2 7.5 0.1 3.2 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) DUF604 PF04646.12 EKX51994.1 - 0.08 12.3 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF604 TPR_19 PF14559.6 EKX51995.1 - 9.5e-14 51.7 1.3 0.0002 21.8 0.1 5.5 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX51995.1 - 9.9e-09 34.7 15.6 0.31 11.2 0.1 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX51995.1 - 2.4e-07 30.9 14.6 0.0015 18.7 2.1 6.0 4 1 3 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 EKX51995.1 - 1.1e-05 25.6 0.9 0.61 10.9 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX51995.1 - 3.9e-05 23.7 0.9 0.17 12.0 0.3 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX51995.1 - 4.9e-05 23.0 18.5 0.68 9.8 0.0 7.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX51995.1 - 9.6e-05 22.9 0.7 6.1 7.9 0.1 5.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX51995.1 - 0.0033 17.3 1.7 0.28 11.3 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX51995.1 - 0.013 16.1 1.2 51 4.6 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX51995.1 - 0.073 13.7 10.1 1.1 10.1 0.1 5.6 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX51995.1 - 0.88 9.9 11.2 13 6.3 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX51995.1 - 2 8.4 4.2 4.3 7.3 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX51995.1 - 4.2 7.7 10.5 3.1 8.2 0.1 5.0 6 1 0 6 6 6 0 Tetratricopeptide repeat zf-C2H2_4 PF13894.6 EKX51996.1 - 3.7e-16 58.4 68.7 0.0044 17.7 3.4 9.1 9 0 0 9 9 8 8 C2H2-type zinc finger zf-C2H2 PF00096.26 EKX51996.1 - 2.6e-15 55.9 58.8 0.0081 16.6 3.6 8.3 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-met PF12874.7 EKX51996.1 - 3.6e-14 52.6 44.3 0.0012 19.2 0.1 8.4 8 0 0 8 8 8 6 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EKX51996.1 - 4.4e-08 33.2 45.0 0.011 16.0 0.1 7.9 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EKX51996.1 - 2.7e-05 24.4 1.3 2.7e-05 24.4 1.3 8.3 9 0 0 9 9 9 3 Zinc-finger double domain FYVE PF01363.21 EKX51996.1 - 8.6e-05 22.6 52.1 0.00079 19.5 7.3 5.3 1 1 2 3 3 2 2 FYVE zinc finger zf-C2H2_3rep PF18868.1 EKX51996.1 - 0.00064 20.4 21.5 1.4 9.6 0.0 4.8 2 1 3 5 5 5 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 EKX51996.1 - 0.02 14.9 3.8 0.02 14.9 3.8 8.0 8 0 0 8 8 8 0 C2H2-type zinc finger zf-AN1 PF01428.16 EKX51996.1 - 0.49 10.6 51.4 1.8 8.8 0.3 7.8 5 1 3 8 8 8 0 AN1-like Zinc finger DUF2256 PF10013.9 EKX51996.1 - 0.53 10.5 35.4 3.8 7.7 0.2 7.8 8 0 0 8 8 8 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2HE PF16278.5 EKX51996.1 - 2.2 8.8 0.0 2.2 8.8 0.0 6.2 4 2 1 6 6 5 0 C2HE / C2H2 / C2HC zinc-binding finger ubiquitin PF00240.23 EKX51997.1 - 0.00015 21.5 0.0 0.058 13.1 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin family LppX_LprAFG PF07161.13 EKX51997.1 - 0.059 13.2 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 LppX_LprAFG lipoprotein AbiJ_NTD5 PF18865.1 EKX51997.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 PRA1 PF03208.19 EKX51998.1 - 5.2e-28 97.5 0.2 6.9e-28 97.1 0.2 1.1 1 0 0 1 1 1 1 PRA1 family protein ERM PF00769.19 EKX51999.1 - 0.66 9.7 6.8 0.3 10.9 2.8 1.9 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Peptidase_C14 PF00656.22 EKX52001.1 - 1.3e-10 41.7 0.0 6.2e-10 39.4 0.0 2.1 2 0 0 2 2 2 1 Caspase domain TPR_19 PF14559.6 EKX52002.1 - 1.2e-15 57.8 1.8 0.00035 21.0 0.2 5.3 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX52002.1 - 1.7e-08 33.9 16.7 0.36 11.1 0.1 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX52002.1 - 3.1e-08 33.7 18.2 0.0018 18.5 2.1 5.4 3 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EKX52002.1 - 4.1e-07 29.5 11.4 0.78 9.7 0.0 6.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_4 PF07721.14 EKX52002.1 - 1e-05 25.7 1.5 0.69 10.7 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX52002.1 - 1.4e-05 25.5 1.1 6.7 7.8 0.0 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX52002.1 - 0.0012 19.0 6.2 0.27 11.4 0.5 4.3 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX52002.1 - 0.0013 19.3 1.0 1.2 9.9 0.0 3.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX52002.1 - 0.0074 16.3 1.4 0.32 11.1 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX52002.1 - 0.031 14.5 4.8 5.3 7.5 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX52002.1 - 0.2 12.4 9.2 17 6.3 0.0 5.4 7 0 0 7 7 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX52002.1 - 0.35 11.2 5.4 3.5 8.0 0.1 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX52002.1 - 3.2 7.8 5.2 4.9 7.2 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Patatin PF01734.22 EKX52004.1 - 2e-06 28.2 0.1 1.6e-05 25.2 0.1 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase COG4 PF08318.12 EKX52005.1 - 0.00048 19.3 0.3 0.00057 19.1 0.3 1.1 1 0 0 1 1 1 1 COG4 transport protein DUF4200 PF13863.6 EKX52005.1 - 0.073 13.5 6.4 0.51 10.7 3.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) TBCA PF02970.16 EKX52005.1 - 0.34 11.3 8.3 0.83 10.0 8.3 1.7 1 1 0 1 1 1 0 Tubulin binding cofactor A DUF5595 PF18077.1 EKX52005.1 - 1.3 9.1 8.7 0.2 11.8 3.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) Methyltransf_16 PF10294.9 EKX52006.1 - 2.8e-05 23.9 0.0 4.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EKX52006.1 - 8.7e-05 22.4 0.0 0.0002 21.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX52006.1 - 9.2e-05 22.3 0.7 0.0011 18.7 0.7 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX52006.1 - 0.00043 20.9 0.3 0.0018 18.9 0.1 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX52006.1 - 0.001 19.8 0.3 0.0036 18.0 0.3 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EKX52006.1 - 0.0047 16.5 0.1 0.0084 15.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EKX52006.1 - 0.013 15.0 0.1 0.019 14.4 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EKX52006.1 - 0.098 13.3 0.4 0.44 11.2 0.1 2.2 1 1 1 2 2 2 0 Methyltransferase domain RWP-RK PF02042.15 EKX52007.1 - 9.3e-16 57.5 0.1 2e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 RWP-RK domain HCMV_UL139 PF12507.8 EKX52008.1 - 0.019 15.4 4.2 0.13 12.7 4.2 2.4 1 1 0 1 1 1 0 Human Cytomegalovirus UL139 protein Laminin_II PF06009.12 EKX52008.1 - 0.055 13.5 8.8 0.058 13.4 1.1 2.3 2 0 0 2 2 2 0 Laminin Domain II Rad21_Rec8 PF04824.16 EKX52008.1 - 0.096 12.0 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein SlyX PF04102.12 EKX52008.1 - 0.18 12.5 10.5 0.69 10.6 0.7 3.5 1 1 2 3 3 3 0 SlyX ApoB100_C PF12491.8 EKX52008.1 - 0.19 11.7 2.8 0.35 10.9 0.7 2.3 2 0 0 2 2 2 0 Apolipoprotein B100 C terminal Spc7 PF08317.11 EKX52008.1 - 3.5 6.4 25.0 1.5 7.6 3.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein YabA PF06156.13 EKX52008.1 - 5.7 7.6 16.3 4.7 7.9 7.9 3.0 1 1 1 2 2 2 0 Initiation control protein YabA EDR1 PF14381.6 EKX52008.1 - 5.8 6.6 9.0 3.3 7.4 1.8 2.1 1 1 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 UPF0242 PF06785.11 EKX52008.1 - 6.6 6.8 21.6 2.3e+02 1.8 19.9 2.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CENP-H PF05837.12 EKX52008.1 - 7 7.1 20.7 0.24 11.8 3.6 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) TMF_DNA_bd PF12329.8 EKX52008.1 - 8.9 6.4 26.6 2.1 8.4 5.4 3.3 2 2 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Acetyltransf_1 PF00583.25 EKX52009.1 - 1.6e-13 50.9 0.0 2.2e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EKX52009.1 - 2.2e-10 40.6 0.0 3.3e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EKX52009.1 - 9.1e-10 38.8 0.0 2e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EKX52009.1 - 1.5e-07 31.3 0.0 3.7e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EKX52009.1 - 0.0047 17.1 0.0 0.01 16.0 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EKX52009.1 - 0.061 13.4 0.0 0.14 12.2 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain ThylakoidFormat PF11264.8 EKX52010.1 - 1.9e-38 132.3 0.0 2.6e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Thylakoid formation protein FinO_N PF12602.8 EKX52010.1 - 2.3 8.6 6.8 5.4 7.4 6.8 1.7 1 0 0 1 1 1 0 Fertility inhibition protein N terminal EGF_2 PF07974.13 EKX52011.1 - 7e-08 32.7 30.6 8.2e-05 22.9 9.5 2.7 3 0 0 3 3 3 2 EGF-like domain EGF_Tenascin PF18720.1 EKX52011.1 - 6.9e-06 26.0 27.7 0.0012 18.9 7.7 2.8 2 1 1 3 3 3 2 Tenascin EGF domain EGF PF00008.27 EKX52011.1 - 0.00088 19.5 3.4 0.00088 19.5 3.4 3.4 2 2 1 3 3 3 2 EGF-like domain hEGF PF12661.7 EKX52011.1 - 0.056 14.1 7.0 0.056 14.1 7.0 4.1 5 0 0 5 5 5 0 Human growth factor-like EGF EB PF01683.18 EKX52011.1 - 4.8 7.5 25.0 0.69 10.2 0.9 3.1 1 1 1 2 2 2 0 EB module cNMP_binding PF00027.29 EKX52012.1 - 2e-38 130.3 0.1 3.7e-16 59.0 0.0 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Dpy-30 PF05186.13 EKX52012.1 - 6.7e-14 51.3 0.0 1.1e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Dpy-30 motif SMN PF06003.12 EKX52012.1 - 0.14 11.4 0.2 0.23 10.7 0.2 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) PSII_Pbs27 PF13326.6 EKX52014.1 - 1.1e-26 93.8 2.5 1.6e-26 93.3 2.5 1.2 1 0 0 1 1 1 1 Photosystem II Pbs27 TAT_signal PF10518.9 EKX52014.1 - 0.0082 15.9 0.7 0.0082 15.9 0.7 2.6 3 0 0 3 3 3 1 TAT (twin-arginine translocation) pathway signal sequence MLTR_LBD PF17765.1 EKX52014.1 - 0.098 12.8 0.0 0.18 11.9 0.0 1.5 1 1 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain UFD1 PF03152.14 EKX52015.1 - 4.4e-71 237.9 0.0 5e-71 237.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_N PF02359.18 EKX52015.1 - 0.0018 18.4 0.0 0.011 15.9 0.0 2.2 2 1 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.17 EKX52015.1 - 0.051 13.4 0.0 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 Molydop_binding PF01568.21 EKX52015.1 - 0.15 12.1 0.0 2.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Molydopterin dinucleotide binding domain ThiF PF00899.21 EKX52016.1 - 4.4e-104 347.2 0.0 3.2e-67 226.4 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EKX52016.1 - 8.3e-79 265.1 0.0 1.3e-78 264.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 EKX52016.1 - 1.1e-31 108.8 0.3 2.6e-31 107.6 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 EKX52016.1 - 3.5e-28 98.1 0.2 2.1e-27 95.6 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin fold domain E1_4HB PF16191.5 EKX52016.1 - 5.5e-18 64.9 0.2 1.3e-17 63.8 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle 2-Hacid_dh_C PF02826.19 EKX52016.1 - 0.0048 16.3 0.0 3.6 6.9 0.0 2.5 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EKX52016.1 - 0.0067 16.5 0.0 0.44 10.6 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase HydF_tetramer PF18133.1 EKX52016.1 - 0.077 12.8 0.1 0.28 11.0 0.1 2.0 1 0 0 1 1 1 0 Hydrogen maturase F tetramerization domain Aconitase PF00330.20 EKX52017.1 - 3.9e-166 553.6 0.0 4.6e-166 553.4 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EKX52017.1 - 2.3e-35 121.8 0.0 4.4e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Gag_p24 PF00607.20 EKX52018.1 - 0.007 16.3 0.1 0.0089 15.9 0.1 1.1 1 0 0 1 1 1 1 gag gene protein p24 (core nucleocapsid protein) ARA70 PF12489.8 EKX52018.1 - 0.034 14.3 0.0 0.046 13.9 0.0 1.2 1 0 0 1 1 1 0 Nuclear coactivator Dynamitin PF04912.14 EKX52020.1 - 0.0049 16.3 0.4 0.0049 16.3 0.4 1.6 2 0 0 2 2 2 1 Dynamitin KH_10 PF17905.1 EKX52021.1 - 0.017 15.6 1.3 0.031 14.7 1.3 1.4 1 0 0 1 1 1 0 GLD-3 KH domain 5 Methyltransf_16 PF10294.9 EKX52022.1 - 2.4e-28 99.0 0.0 2.8e-28 98.8 0.0 1.0 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 EKX52022.1 - 5.1e-09 36.0 0.0 6.7e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EKX52022.1 - 5.5e-08 33.4 0.0 7.9e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX52022.1 - 1.9e-07 31.7 0.0 2.5e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX52022.1 - 2.4e-07 30.7 0.0 3.1e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX52022.1 - 9.7e-07 29.5 0.0 1.6e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX52022.1 - 2.9e-06 27.1 0.0 4.7e-06 26.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EKX52022.1 - 9.9e-06 25.2 0.0 2.4e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 EKX52022.1 - 0.0016 18.1 0.0 0.0021 17.7 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 NNMT_PNMT_TEMT PF01234.17 EKX52022.1 - 0.0077 15.5 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_18 PF12847.7 EKX52022.1 - 0.025 14.5 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.11 EKX52022.1 - 0.039 13.6 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) PCMT PF01135.19 EKX52022.1 - 0.15 11.8 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pkinase_Tyr PF07714.17 EKX52023.1 - 4.4e-38 131.0 0.0 5.4e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX52023.1 - 7.6e-38 130.4 0.0 9.4e-38 130.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EKX52023.1 - 0.036 14.0 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX52023.1 - 0.054 12.3 0.0 0.075 11.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EKX52023.1 - 0.16 11.3 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-CCHH PF10283.9 EKX52023.1 - 0.55 10.3 3.5 2.6 8.1 0.1 2.6 2 0 0 2 2 2 0 PBZ domain Ribosomal_S18 PF01084.20 EKX52025.1 - 8.2e-17 61.2 0.7 9.9e-17 60.9 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S18 Mito_carr PF00153.27 EKX52026.1 - 2.3e-64 213.4 2.3 9.8e-22 76.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Vps16_C PF04840.12 EKX52027.1 - 8.1e-09 34.9 0.0 0.0024 17.0 0.0 2.2 2 0 0 2 2 2 2 Vps16, C-terminal region CCDC-167 PF15188.6 EKX52029.1 - 0.57 10.6 2.7 1.7 9.1 1.0 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Exo_endo_phos PF03372.23 EKX52031.1 - 3.4e-07 30.0 0.2 3.1e-06 26.9 0.1 2.1 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EKX52031.1 - 2.3e-05 24.2 0.0 9.1e-05 22.3 0.0 2.0 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase BRCT_2 PF16589.5 EKX52031.1 - 0.11 12.9 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Bromodomain PF00439.25 EKX52032.1 - 4.6e-11 42.6 1.6 2e-07 31.0 0.3 2.1 2 0 0 2 2 2 2 Bromodomain PDZ_2 PF13180.6 EKX52034.1 - 1.3e-12 47.8 0.1 1.4e-05 25.3 0.0 2.8 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EKX52034.1 - 1.2e-11 44.3 0.2 8.6e-08 31.9 0.0 2.8 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 EKX52034.1 - 3.9e-08 33.5 0.1 8.7e-05 22.8 0.0 2.9 2 0 0 2 2 2 2 PDZ domain LANC_like PF05147.13 EKX52035.1 - 7.8e-13 47.7 0.1 8.8e-13 47.6 0.1 1.0 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein DSS1_SEM1 PF05160.13 EKX52036.1 - 0.025 14.7 1.3 0.034 14.2 1.3 1.3 1 0 0 1 1 1 0 DSS1/SEM1 family Trypan_PARP PF05887.11 EKX52037.1 - 0.00012 22.0 44.7 0.015 15.3 20.5 2.1 1 1 1 2 2 2 2 Procyclic acidic repetitive protein (PARP) NESP55 PF06390.12 EKX52037.1 - 0.037 13.6 40.2 1.2e+03 -1.2 40.2 2.3 1 1 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) BBP2_2 PF10082.9 EKX52037.1 - 0.16 10.8 3.4 0.19 10.5 3.4 1.2 1 0 0 1 1 1 0 Putative beta-barrel porin 2 DUF2807 PF10988.8 EKX52037.1 - 0.47 10.2 13.4 17 5.2 13.3 2.3 1 1 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain Paf1 PF03985.13 EKX52037.1 - 0.49 9.3 30.8 0.75 8.7 30.8 1.3 1 0 0 1 1 1 0 Paf1 Cwf_Cwc_15 PF04889.12 EKX52037.1 - 1.5 8.5 22.3 1.9 8.2 22.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4045 PF13254.6 EKX52037.1 - 2.4 7.7 15.7 2.6 7.6 15.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) LAP1C PF05609.12 EKX52037.1 - 4.2 6.4 16.2 4.6 6.2 16.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Med15 PF09606.10 EKX52037.1 - 4.6 5.8 10.5 52 2.3 10.5 1.9 1 1 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Lin-8 PF03353.15 EKX52037.1 - 4.9 6.6 17.3 5.8 6.4 17.3 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.12 EKX52037.1 - 8.8 4.4 27.7 10 4.2 27.7 1.0 1 0 0 1 1 1 0 Nop14-like family LANC_like PF05147.13 EKX52038.1 - 9.9e-05 21.1 0.0 0.00013 20.7 0.0 1.1 1 0 0 1 1 1 1 Lanthionine synthetase C-like protein DRMBL PF07522.14 EKX52039.1 - 4.9e-23 81.4 0.0 7.6e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EKX52039.1 - 0.00012 21.6 0.1 0.00022 20.8 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.12 EKX52039.1 - 0.00022 21.1 0.0 0.00047 20.0 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 EKX52039.1 - 0.12 12.3 0.1 0.3 11.1 0.0 1.6 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Med4 PF10018.9 EKX52040.1 - 4.1e-09 36.4 3.8 4.1e-09 36.4 3.8 2.0 2 1 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 IKBKB_SDD PF18397.1 EKX52040.1 - 0.00039 19.8 5.8 0.0034 16.7 0.7 2.2 2 0 0 2 2 2 2 IQBAL scaffold dimerization domain 1-cysPrx_C PF10417.9 EKX52040.1 - 0.013 15.3 1.7 0.64 9.9 1.0 2.9 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin Mce4_CUP1 PF11887.8 EKX52040.1 - 0.18 11.2 0.6 0.85 9.0 0.1 1.9 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative DASH_Duo1 PF08651.10 EKX52040.1 - 0.21 11.4 2.2 1.3 8.9 0.1 2.5 2 0 0 2 2 2 0 DASH complex subunit Duo1 Prominin PF05478.11 EKX52040.1 - 0.31 8.9 2.6 0.51 8.2 2.6 1.3 1 0 0 1 1 1 0 Prominin DUF4542 PF15075.6 EKX52041.1 - 1.3e-05 25.6 0.2 2.2e-05 24.8 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4542) Nop25 PF09805.9 EKX52041.1 - 8.9 6.8 27.2 0.24 11.9 20.3 1.8 1 1 1 2 2 2 0 Nucleolar protein 12 (25kDa) PapD-like PF14874.6 EKX52042.1 - 1.5e-11 44.3 0.0 2.1e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Flagellar-associated PapD-like DUF1573 PF07610.11 EKX52042.1 - 0.0034 17.4 0.0 0.0053 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1573) ASH PF15780.5 EKX52042.1 - 0.098 12.9 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin AhpC-TSA_2 PF13911.6 EKX52044.1 - 0.03 14.4 0.0 0.069 13.3 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme MORN PF02493.20 EKX52045.1 - 2.7e-10 39.5 5.3 5.1e-08 32.3 1.1 2.5 2 0 0 2 2 2 2 MORN repeat JmjC PF02373.22 EKX52046.1 - 4.2e-35 120.6 2.0 4.9e-35 120.4 0.1 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.17 EKX52046.1 - 4.2e-15 55.4 0.9 1.3e-14 53.9 0.9 1.9 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H_2 PF13832.6 EKX52046.1 - 1.8e-12 47.4 7.2 1.8e-12 47.4 7.2 3.5 2 1 1 3 3 3 1 PHD-zinc-finger like domain ARID PF01388.21 EKX52046.1 - 4.5e-12 46.5 0.0 1.5e-11 44.8 0.0 2.0 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 EKX52046.1 - 1.6e-10 40.7 11.0 1.6e-10 40.7 11.0 4.1 4 0 0 4 4 4 2 PHD-finger zf-C5HC2 PF02928.16 EKX52046.1 - 1.5e-09 38.1 6.3 1.5e-09 38.1 6.3 3.6 3 0 0 3 3 3 1 C5HC2 zinc finger zf-HC5HC2H PF13771.6 EKX52046.1 - 4.7e-07 30.0 9.9 4.7e-07 30.0 9.9 4.8 2 1 2 4 4 4 2 PHD-like zinc-binding domain PHD_2 PF13831.6 EKX52046.1 - 0.00017 21.1 4.9 0.00017 21.1 4.9 3.8 4 0 0 4 4 4 1 PHD-finger Toprim_Crpt PF13342.6 EKX52046.1 - 0.095 12.7 0.8 0.35 10.9 0.2 2.3 2 0 0 2 2 2 0 C-terminal repeat of topoisomerase Pkinase_Tyr PF07714.17 EKX52048.1 - 9.8e-45 152.8 0.0 1.7e-44 152.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX52048.1 - 2.1e-37 128.9 0.0 3.3e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain EF-hand_7 PF13499.6 EKX52048.1 - 2.5e-16 59.9 8.8 0.00029 21.2 0.1 4.7 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.32 EKX52048.1 - 1.9e-15 55.2 13.8 0.00019 20.7 0.1 5.6 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 EKX52048.1 - 1e-14 53.1 15.0 0.0023 17.7 0.2 5.8 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 EKX52048.1 - 8.4e-07 28.2 7.6 0.009 15.5 0.1 4.6 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EKX52048.1 - 7.1e-06 25.8 12.8 3.8e-05 23.4 0.1 3.4 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_4 PF12763.7 EKX52048.1 - 0.00011 22.1 0.1 0.058 13.3 0.1 3.0 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand APH PF01636.23 EKX52048.1 - 0.024 14.5 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX52048.1 - 0.063 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FOP_dimer PF09398.10 EKX52049.1 - 2.4e-11 43.7 0.0 6.2e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 FOP N terminal dimerisation domain CHASE3 PF05227.13 EKX52049.1 - 0.079 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 CHASE3 domain Spc24 PF08286.11 EKX52051.1 - 3.8e-07 30.3 2.4 3.8e-07 30.3 2.4 2.0 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 DUF1664 PF07889.12 EKX52051.1 - 0.006 16.6 3.8 0.006 16.6 3.8 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 EKX52051.1 - 0.015 15.6 1.4 0.015 15.6 1.4 2.8 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) CASP_C PF08172.12 EKX52051.1 - 0.026 13.8 9.6 0.036 13.4 9.6 1.1 1 0 0 1 1 1 0 CASP C terminal DUF4407 PF14362.6 EKX52051.1 - 0.075 12.4 7.9 0.095 12.0 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DZF PF07528.14 EKX52051.1 - 0.12 12.0 3.8 0.15 11.6 3.8 1.2 1 0 0 1 1 1 0 DZF domain DUF5383 PF17355.2 EKX52051.1 - 0.22 11.9 9.3 0.32 11.4 9.0 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5383) AAA_23 PF13476.6 EKX52051.1 - 0.64 10.5 15.7 0.95 9.9 15.7 1.2 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 EKX52051.1 - 1 8.2 17.0 1.3 7.8 17.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 EKX52051.1 - 1.2 9.2 15.9 1.9 8.5 15.9 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FlxA PF14282.6 EKX52051.1 - 1.5 8.9 15.8 0.34 10.9 11.8 2.0 1 1 0 1 1 1 0 FlxA-like protein TMPIT PF07851.13 EKX52051.1 - 1.6 7.9 10.2 2.1 7.5 9.8 1.5 1 1 1 2 2 2 0 TMPIT-like protein V_ATPase_I PF01496.19 EKX52051.1 - 2.5 5.9 9.0 2.9 5.7 9.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 EKX52051.1 - 2.6 7.1 9.8 3.4 6.7 9.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TssO PF17561.2 EKX52051.1 - 4.4 7.4 12.3 11 6.1 6.8 2.2 1 1 1 2 2 2 0 Type VI secretion system, TssO DUF948 PF06103.11 EKX52051.1 - 4.7 7.5 7.5 1 9.6 1.8 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) 5_nucleotid PF05761.14 EKX52051.1 - 7.4 5.3 9.4 13 4.5 9.4 1.5 1 1 0 1 1 1 0 5' nucleotidase family APG6_N PF17675.1 EKX52051.1 - 8.8 6.9 19.5 26 5.3 19.5 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region Pkinase PF00069.25 EKX52053.1 - 2.3e-31 109.1 0.0 2.9e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX52053.1 - 2e-14 53.5 0.0 2.5e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX52053.1 - 0.01 15.8 0.1 0.013 15.5 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family U-box PF04564.15 EKX52054.1 - 1.1e-18 67.2 0.1 1.3e-18 67.0 0.1 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX52054.1 - 0.04 13.7 0.2 0.074 12.9 0.2 1.4 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Pkinase_Tyr PF07714.17 EKX52055.1 - 9.2e-20 71.0 0.0 1.1e-19 70.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX52055.1 - 4e-11 42.8 0.0 4.8e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EKX52055.1 - 0.065 12.6 0.0 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 EKX52056.1 - 2.7e-24 85.9 0.1 2.9e-24 85.7 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX52056.1 - 6.8e-11 42.0 0.0 8.4e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Atx10homo_assoc PF09759.9 EKX52057.1 - 9.7e-06 25.5 0.0 0.12 12.4 0.1 3.7 2 2 2 4 4 4 3 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 EKX52057.1 - 5.6e-05 23.0 0.0 0.91 9.7 0.0 4.5 4 1 0 5 5 5 2 Armadillo/beta-catenin-like repeat KH_4 PF13083.6 EKX52057.1 - 0.0092 15.8 0.5 10 6.0 0.2 4.1 4 1 1 5 5 5 1 KH domain DUF3361 PF11841.8 EKX52057.1 - 0.043 13.8 0.0 0.8 9.6 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3361) Phage_GP20 PF06810.11 EKX52058.1 - 0.025 14.4 0.4 0.025 14.4 0.4 2.7 2 1 1 3 3 3 0 Phage minor structural protein GP20 Defensin_int PF17858.1 EKX52058.1 - 0.058 13.4 1.6 0.11 12.5 0.2 2.2 2 0 0 2 2 2 0 Platypus intermediate defensin-like peptide GAS PF13851.6 EKX52058.1 - 0.061 12.7 11.6 0.48 9.8 2.9 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 EKX52058.1 - 2.7 7.8 12.3 0.63 9.8 0.7 3.0 2 1 1 3 3 3 0 Septum formation initiator CRAL_TRIO_N PF03765.15 EKX52058.1 - 3.5 7.9 6.0 5.3 7.3 0.8 3.1 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain LRR_6 PF13516.6 EKX52059.1 - 5.8e-19 66.5 21.4 1.5e-05 24.7 0.0 9.7 10 0 0 10 10 10 4 Leucine Rich repeat LRR_4 PF12799.7 EKX52059.1 - 4e-12 46.2 9.0 0.12 12.8 1.4 6.6 4 3 4 8 8 8 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX52059.1 - 0.00059 20.0 22.1 2.7 8.9 0.1 8.6 8 2 0 8 8 8 2 Leucine Rich Repeat MBD PF01429.19 EKX52059.1 - 0.0023 17.6 0.0 0.0051 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyl-CpG binding domain DUF5089 PF17002.5 EKX52059.1 - 0.13 12.2 0.2 0.23 11.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) LRR_8 PF13855.6 EKX52059.1 - 0.38 10.5 9.4 12 5.8 0.4 5.0 5 1 1 6 6 6 0 Leucine rich repeat ADK PF00406.22 EKX52061.1 - 5.2e-43 146.7 0.0 6.1e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EKX52061.1 - 3.9e-33 114.7 0.0 5e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EKX52061.1 - 1.7e-09 38.3 0.0 2.7e-09 37.7 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EKX52061.1 - 4.1e-08 33.5 0.0 9.1e-08 32.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EKX52061.1 - 0.015 15.0 0.1 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase Cytidylate_kin PF02224.18 EKX52061.1 - 0.087 12.5 0.0 1.7 8.4 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase AAA_19 PF13245.6 EKX52061.1 - 0.14 12.5 0.2 0.14 12.5 0.2 1.5 1 1 0 1 1 1 0 AAA domain CitMHS PF03600.16 EKX52062.1 - 1.3e-53 182.1 27.1 1.3e-53 182.1 27.1 1.9 1 1 1 2 2 2 1 Citrate transporter Na_sulph_symp PF00939.19 EKX52062.1 - 2.9e-14 53.0 29.7 6.1e-13 48.6 14.4 2.1 1 1 1 2 2 2 2 Sodium:sulfate symporter transmembrane region ArsB PF02040.15 EKX52062.1 - 1.2e-08 34.7 23.7 1.7e-08 34.3 23.7 1.1 1 0 0 1 1 1 1 Arsenical pump membrane protein DUF969 PF06149.12 EKX52062.1 - 7.8 5.9 14.1 0.098 12.1 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF969) Acetyltransf_1 PF00583.25 EKX52063.1 - 1.3e-14 54.4 0.0 1.7e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EKX52063.1 - 1.2e-12 47.8 0.1 3.2e-12 46.5 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EKX52063.1 - 6.2e-10 39.4 0.1 9e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EKX52063.1 - 8.7e-05 22.6 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EKX52063.1 - 0.0021 18.1 0.2 0.0038 17.3 0.2 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_16 PF05301.11 EKX52063.1 - 0.014 15.2 0.1 0.016 15.0 0.1 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 Acetyltransf_8 PF13523.6 EKX52063.1 - 0.024 14.3 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 EKX52063.1 - 0.046 13.7 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein MoaF PF10703.9 EKX52063.1 - 0.058 13.3 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 MoaF N-terminal domain Acetyltransf_13 PF13880.6 EKX52063.1 - 0.084 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase TPR_2 PF07719.17 EKX52064.1 - 4e-08 32.8 0.0 0.00079 19.4 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX52064.1 - 1.4e-06 28.9 0.2 2.6e-06 28.0 0.1 1.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX52064.1 - 2.6e-06 27.8 0.1 10 6.7 0.0 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX52064.1 - 5.7e-06 26.3 0.0 0.22 12.0 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX52064.1 - 5.8e-06 25.9 0.0 0.00029 20.4 0.0 2.1 1 1 1 2 2 2 1 TPR repeat TPR_14 PF13428.6 EKX52064.1 - 6e-06 26.6 1.4 0.001 19.7 0.5 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX52064.1 - 8e-05 22.7 0.6 0.00039 20.5 0.9 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX52064.1 - 0.00066 19.7 0.0 0.41 11.0 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX52064.1 - 0.0019 18.5 0.6 0.021 15.1 0.1 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX52064.1 - 0.0037 17.2 0.1 0.26 11.4 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF5588 PF17826.1 EKX52064.1 - 0.021 13.7 0.0 0.026 13.4 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5588) TPR_1 PF00515.28 EKX52064.1 - 0.025 14.4 0.0 1.8 8.5 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.8 EKX52064.1 - 0.028 13.3 0.0 0.032 13.2 0.0 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PEP-utilisers_N PF05524.13 EKX52064.1 - 0.038 14.1 0.1 0.047 13.9 0.1 1.1 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal TPR_6 PF13174.6 EKX52064.1 - 0.078 13.6 0.5 26 5.7 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX52064.1 - 0.22 11.4 1.8 0.49 10.3 0.2 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PB1 PF00564.24 EKX52065.1 - 1.1e-09 38.1 0.1 2.4e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 PB1 domain DUF5344 PF17279.2 EKX52066.1 - 0.00094 19.7 8.2 0.23 12.0 0.2 3.6 2 1 1 3 3 3 2 Family of unknown function (DUF5344) DUF148 PF02520.17 EKX52066.1 - 0.011 15.8 0.6 0.011 15.8 0.6 2.6 2 2 0 2 2 2 0 Domain of unknown function DUF148 Csm1_N PF18504.1 EKX52066.1 - 0.044 14.1 0.3 0.044 14.1 0.3 5.4 3 1 4 7 7 7 0 Csm1 N-terminal domain TSC22 PF01166.18 EKX52066.1 - 0.42 11.0 0.0 0.42 11.0 0.0 4.5 4 2 2 6 6 6 0 TSC-22/dip/bun family LXG PF04740.12 EKX52066.1 - 0.93 9.2 18.1 0.098 12.4 3.1 3.4 2 1 0 3 3 3 0 LXG domain of WXG superfamily Death PF00531.22 EKX52066.1 - 1.6 9.0 7.7 0.21 11.8 0.3 3.1 2 1 1 3 3 3 0 Death domain Mito_carr PF00153.27 EKX52067.1 - 2.6e-30 104.2 1.9 7.9e-11 41.7 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein ABC2_membrane_2 PF12679.7 EKX52068.1 - 0.12 11.7 0.0 0.12 11.7 0.0 2.0 3 0 0 3 3 3 0 ABC-2 family transporter protein UQ_con PF00179.26 EKX52069.1 - 2.5e-16 59.6 0.0 5.3e-16 58.5 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme EABR PF12180.8 EKX52069.1 - 0.075 12.7 0.2 0.13 11.9 0.2 1.4 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 NtA PF03146.15 EKX52069.1 - 0.19 11.6 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 Agrin NtA domain Tmemb_170 PF10190.9 EKX52071.1 - 0.012 16.0 12.7 0.15 12.4 5.7 2.4 1 1 0 2 2 2 0 Putative transmembrane protein 170 Romo1 PF10247.9 EKX52071.1 - 0.026 14.9 1.2 0.026 14.9 1.2 1.9 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 FUSC PF04632.12 EKX52071.1 - 0.38 9.2 6.3 0.52 8.8 6.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4191 PF13829.6 EKX52071.1 - 0.43 9.9 2.9 0.55 9.5 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Gly-zipper_Omp PF13488.6 EKX52071.1 - 0.63 10.1 5.1 1.7 8.7 5.1 1.7 1 0 0 1 1 1 0 Glycine zipper DHHC PF01529.20 EKX52071.1 - 0.69 10.0 3.8 0.28 11.3 0.9 1.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase FtsX PF02687.21 EKX52071.1 - 0.78 10.3 13.6 2.1 8.9 10.4 2.1 2 0 0 2 2 2 0 FtsX-like permease family DUF3169 PF11368.8 EKX52071.1 - 1.4 8.3 10.3 0.21 11.1 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) CPP1-like PF11833.8 EKX52071.1 - 2.4 7.8 6.4 2.1 8.0 4.8 1.7 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Gly_transf_sug PF04488.15 EKX52073.1 - 0.00041 20.9 0.0 0.00081 20.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif RWP-RK PF02042.15 EKX52074.1 - 5.4e-13 48.7 0.0 1e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain HCV_NS5a PF01506.19 EKX52077.1 - 0.0093 15.8 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Hepatitis C virus non-structural 5a protein membrane anchor TruD PF01142.18 EKX52079.1 - 9.2e-52 176.2 0.0 4.8e-48 164.0 0.0 2.1 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Nod1 PF17114.5 EKX52079.1 - 0.092 12.9 0.4 1.1 9.4 0.0 2.5 3 0 0 3 3 3 0 Gef2-related medial cortical node protein Nod1 Methyltransf_16 PF10294.9 EKX52080.1 - 3.9e-06 26.7 0.0 4.6e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EKX52080.1 - 0.022 14.6 0.0 0.028 14.2 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain F5_F8_type_C PF00754.25 EKX52081.1 - 1.1e-05 25.5 13.3 0.0039 17.3 0.8 3.2 2 2 2 4 4 4 2 F5/8 type C domain RtxA PF07634.11 EKX52081.1 - 0.11 13.0 0.2 33 5.3 0.0 2.6 2 0 0 2 2 2 0 RtxA repeat DUF3978 PF13123.6 EKX52081.1 - 0.15 11.8 0.0 15 5.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3978) PLD_C PF12357.8 EKX52081.1 - 0.15 12.0 0.0 33 4.5 0.0 2.6 2 0 0 2 2 2 0 Phospholipase D C terminal DUF943 PF06092.12 EKX52081.1 - 1.3 8.6 5.3 6.7 6.4 0.2 2.4 2 0 0 2 2 2 0 Enterobacterial putative membrane protein (DUF943) Ank_4 PF13637.6 EKX52082.1 - 2.3e-17 63.1 0.1 4.5e-10 39.9 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX52082.1 - 9.5e-15 55.0 0.0 1.8e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX52082.1 - 4.9e-13 48.9 0.2 3.4e-06 27.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EKX52082.1 - 2.5e-12 46.7 0.1 2.8e-06 27.5 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX52082.1 - 7.7e-12 44.3 0.1 0.00025 21.3 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat DUF4695 PF15766.5 EKX52082.1 - 0.055 13.7 0.2 0.15 12.3 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4695) Cyto_heme_lyase PF01265.17 EKX52083.1 - 2.2e-43 149.0 10.0 1.8e-42 146.0 10.0 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Ubiq_cyt_C_chap PF03981.12 EKX52084.1 - 2e-28 99.3 0.0 3.1e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Peptidase_M20 PF01546.28 EKX52085.1 - 1e-22 80.9 0.0 1.5e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EKX52085.1 - 2.1e-11 43.7 0.0 1.1e-10 41.4 0.0 2.1 2 1 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EKX52085.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 Pkinase PF00069.25 EKX52086.1 - 4.7e-59 199.9 0.0 7.2e-59 199.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX52086.1 - 4.7e-30 104.7 0.0 1.1e-29 103.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX52086.1 - 2.6e-05 23.2 0.8 6.7e-05 21.8 0.8 1.7 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EKX52086.1 - 7.5e-05 22.2 0.0 0.00029 20.3 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EKX52086.1 - 0.0077 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 EKX52086.1 - 0.0093 16.1 0.0 0.028 14.6 0.0 1.8 1 0 0 1 1 1 1 ABC1 family FTA2 PF13095.6 EKX52086.1 - 0.014 15.1 0.0 0.049 13.3 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EKX52086.1 - 0.018 15.0 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EKX52086.1 - 0.077 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 EKX52086.1 - 0.11 12.0 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 RIO1 family TPR_2 PF07719.17 EKX52087.1 - 0.00029 20.7 1.4 0.074 13.2 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX52087.1 - 0.00036 21.1 0.4 0.011 16.4 0.4 2.3 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX52087.1 - 0.0012 18.6 4.5 0.11 12.4 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX52087.1 - 0.0067 17.0 0.8 0.95 10.2 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX52087.1 - 0.012 15.3 0.9 0.074 12.8 0.1 2.5 2 1 1 3 3 3 0 TPR repeat TPR_14 PF13428.6 EKX52087.1 - 0.016 16.0 0.1 2.5 9.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX52087.1 - 0.028 14.6 0.9 6.1 7.3 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX52087.1 - 0.032 14.7 0.0 2.5 8.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EKX52087.1 - 0.073 13.1 0.1 16 5.8 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 EKX52087.1 - 0.27 11.3 7.1 1.1 9.3 0.7 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltransf_31 PF13847.6 EKX52088.1 - 4.5e-18 65.5 0.0 5.9e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX52088.1 - 2.6e-16 60.1 0.0 4e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX52088.1 - 3.3e-16 59.8 0.0 5.4e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX52088.1 - 1.5e-15 57.7 0.0 2.3e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX52088.1 - 6e-12 45.7 0.0 7.1e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EKX52088.1 - 1.6e-07 31.1 0.0 2.4e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 EKX52088.1 - 2.2e-06 27.3 0.0 5.4e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EKX52088.1 - 5.7e-05 22.7 0.0 8.3e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 EKX52088.1 - 0.0001 22.0 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 EKX52088.1 - 0.00014 21.3 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 EKX52088.1 - 0.0012 19.9 0.0 0.0021 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Rsm22 PF09243.10 EKX52088.1 - 0.0042 16.4 0.1 0.0052 16.1 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_32 PF13679.6 EKX52088.1 - 0.0052 16.8 0.0 0.0069 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 EKX52088.1 - 0.019 14.4 0.0 5.1 6.5 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_16 PF10294.9 EKX52088.1 - 0.025 14.3 0.5 0.19 11.4 0.5 2.1 1 1 0 1 1 1 0 Lysine methyltransferase U62_UL91 PF17442.2 EKX52088.1 - 0.042 13.8 0.0 0.094 12.7 0.0 1.6 1 0 0 1 1 1 0 Functional domain of U62 and UL91 proteins TehB PF03848.14 EKX52088.1 - 0.054 12.9 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB UPF0020 PF01170.18 EKX52088.1 - 0.08 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 FWWh PF14922.6 EKX52089.1 - 2.7e-32 111.7 0.2 4.5e-32 111.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF4085 PF13315.6 EKX52089.1 - 0.017 14.7 0.5 0.22 11.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4085) Pox_A12 PF04651.13 EKX52089.1 - 0.019 15.0 2.4 0.058 13.4 1.5 2.0 2 0 0 2 2 2 0 Poxvirus A12 protein Trimer_CC PF08954.11 EKX52089.1 - 0.033 13.7 0.2 0.033 13.7 0.2 3.1 3 0 0 3 3 3 0 Trimerisation motif LPP PF04728.13 EKX52089.1 - 0.18 12.2 1.9 0.28 11.6 0.5 2.1 2 0 0 2 2 2 0 Lipoprotein leucine-zipper COG2 PF06148.11 EKX52089.1 - 0.57 10.3 3.3 9 6.4 0.2 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FTHFS PF01268.19 EKX52090.1 - 1.8e-172 574.4 0.2 8.2e-172 572.3 0.2 1.8 1 1 0 1 1 1 1 Formate--tetrahydrofolate ligase Prenyltrans PF00432.21 EKX52091.1 - 6.3e-72 237.0 18.5 1.8e-15 56.3 0.1 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 EKX52091.1 - 6.2e-06 25.5 0.0 0.00085 18.5 0.0 2.5 1 1 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EKX52091.1 - 2.2e-05 23.7 0.0 0.12 11.5 0.0 3.7 1 1 4 5 5 5 4 Squalene-hopene cyclase N-terminal domain TFIIS_M PF07500.14 EKX52092.1 - 6.5e-14 52.4 0.1 1.2e-13 51.5 0.1 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain HEXIM PF15313.6 EKX52093.1 - 0.00015 22.0 13.0 0.0015 18.7 8.6 2.6 2 1 0 2 2 2 1 Hexamethylene bis-acetamide-inducible protein cNMP_binding PF00027.29 EKX52094.1 - 1.7e-10 40.8 0.0 2.8e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF5572 PF17733.1 EKX52094.1 - 0.058 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5572) RRM_1 PF00076.22 EKX52095.1 - 8.9e-06 25.4 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_1 PF00013.29 EKX52096.1 - 2.1e-09 37.1 3.5 2.1e-09 37.1 3.5 2.1 2 0 0 2 2 2 1 KH domain KH_2 PF07650.17 EKX52096.1 - 0.00029 20.6 1.5 0.001 18.9 1.5 1.9 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 EKX52096.1 - 0.35 10.8 2.7 0.32 10.9 0.5 2.1 2 0 0 2 2 2 0 KH domain Parvo_coat PF00740.18 EKX52096.1 - 0.64 8.6 3.0 0.83 8.2 3.0 1.2 1 0 0 1 1 1 0 Parvovirus coat protein VP2 L_lactis_ph-MCP PF06673.11 EKX52096.1 - 1.2 8.1 9.1 2.1 7.3 9.1 1.4 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein RR_TM4-6 PF06459.12 EKX52096.1 - 1.8 8.3 25.6 2.7 7.8 25.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 LRR_4 PF12799.7 EKX52097.1 - 6.4e-16 58.2 40.9 9.2e-06 25.9 0.2 4.6 2 2 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX52097.1 - 2.8e-15 55.8 18.4 9.8e-06 25.2 0.7 3.8 1 1 3 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 EKX52097.1 - 4.8e-05 22.9 9.1 0.0092 15.5 1.8 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 EKX52097.1 - 0.00025 21.2 10.8 1.7 9.5 0.1 5.9 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_3 PF07725.12 EKX52097.1 - 7.8 6.5 6.9 17 5.4 0.2 3.6 3 0 0 3 3 3 0 Leucine Rich Repeat PX PF00787.24 EKX52098.1 - 1.3e-19 70.3 0.1 1.5e-19 70.0 0.1 1.0 1 0 0 1 1 1 1 PX domain Mitoc_L55 PF09776.9 EKX52098.1 - 0.058 13.1 0.2 0.3 10.8 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L55 Bac_rhodopsin PF01036.18 EKX52099.1 - 6.8e-16 58.5 13.6 9.2e-16 58.1 13.6 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein FIN1 PF17300.2 EKX52099.1 - 0.046 13.2 0.4 0.065 12.7 0.4 1.2 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 DUF4303 PF14136.6 EKX52099.1 - 0.12 12.1 0.1 0.19 11.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) TACC_C PF05010.14 EKX52100.1 - 0.0011 18.8 17.0 0.0011 18.8 17.0 3.7 1 1 2 3 3 3 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Img2 PF05046.14 EKX52100.1 - 6.2 7.2 11.8 48 4.3 0.0 4.2 3 1 1 4 4 4 0 Mitochondrial large subunit ribosomal protein (Img2) Glyco_transf_22 PF03901.17 EKX52101.1 - 7.5e-41 140.7 26.0 8.6e-41 140.5 26.0 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family RFC1 PF08519.12 EKX52101.1 - 0.11 12.7 0.3 0.31 11.2 0.1 1.9 2 0 0 2 2 2 0 Replication factor RFC1 C terminal domain RNA_pol_Rpb4 PF03874.16 EKX52102.1 - 1.2e-11 44.9 0.2 1.9e-11 44.3 0.2 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb4 SPRY PF00622.28 EKX52103.1 - 1.8e-06 28.0 0.0 2.6e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 SPRY domain Malt_amylase_C PF16657.5 EKX52103.1 - 0.055 13.6 0.1 0.15 12.2 0.0 1.7 2 0 0 2 2 2 0 Maltogenic Amylase, C-terminal domain Proteasome PF00227.26 EKX52104.1 - 7.1e-57 192.0 0.9 8.7e-57 191.7 0.9 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EKX52104.1 - 2e-14 52.9 0.0 3.6e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Peptidase_C71 PF12386.8 EKX52104.1 - 0.063 12.9 0.2 0.1 12.2 0.2 1.3 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei SbcCD_C PF13558.6 EKX52104.1 - 0.078 13.2 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit zf-C3HC4_3 PF13920.6 EKX52105.1 - 4.2e-14 52.1 10.1 7.6e-14 51.3 10.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX52105.1 - 1.9e-07 30.8 10.4 3.3e-07 30.1 10.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EKX52105.1 - 7.8e-07 28.9 7.1 7.1e-06 25.8 6.5 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX52105.1 - 0.00015 21.7 10.8 0.00027 20.8 10.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EKX52105.1 - 0.00084 19.1 11.6 0.00092 19.0 10.4 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX52105.1 - 0.0015 18.8 12.7 0.002 18.5 10.8 2.0 1 1 1 2 2 2 2 Ring finger domain zf-RING_UBOX PF13445.6 EKX52105.1 - 1.2 9.3 10.8 1.4 9.0 3.3 2.4 2 0 0 2 2 2 0 RING-type zinc-finger Sgf11 PF08209.11 EKX52105.1 - 9.7 5.9 9.8 23 4.7 0.7 3.2 2 1 1 3 3 3 0 Sgf11 (transcriptional regulation protein) Esterase PF00756.20 EKX52106.1 - 4.2e-56 190.4 0.0 4.8e-56 190.2 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 EKX52106.1 - 9e-06 25.1 0.0 1.8e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EKX52106.1 - 0.00011 21.7 0.1 0.00015 21.3 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 EKX52106.1 - 0.00059 18.8 0.0 0.00086 18.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DLH PF01738.18 EKX52106.1 - 0.00064 19.3 0.3 0.0024 17.4 0.3 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Chlorophyllase PF07224.11 EKX52106.1 - 0.0011 18.0 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_1 PF00561.20 EKX52106.1 - 0.0087 15.7 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 EKX52106.1 - 0.17 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) 2OG-FeII_Oxy_3 PF13640.6 EKX52107.1 - 3.3e-18 66.3 0.0 5.6e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EKX52107.1 - 0.00015 22.2 0.0 0.00028 21.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_4 PF13637.6 EKX52108.1 - 5.3e-16 58.8 0.3 1.8e-10 41.2 0.1 3.6 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX52108.1 - 2.7e-12 46.5 1.1 0.00059 20.2 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EKX52108.1 - 9.6e-12 44.0 0.6 0.00088 19.5 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 EKX52108.1 - 1.1e-11 45.2 0.1 3.3e-11 43.6 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX52108.1 - 3.8e-09 36.6 2.0 0.0001 22.5 0.1 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) DUF1415 PF07209.12 EKX52109.1 - 1.8e-07 31.0 0.0 5.5e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1415) Pox_J1 PF03338.15 EKX52109.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Poxvirus J1 protein zf-ribbon_3 PF13248.6 EKX52110.1 - 0.0082 15.5 3.1 0.03 13.8 3.1 1.9 1 1 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 EKX52110.1 - 0.015 15.3 0.5 0.022 14.8 0.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 EKX52110.1 - 0.059 13.1 3.7 1.5 8.7 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 EKX52110.1 - 0.58 10.3 3.6 14 5.8 0.1 2.2 1 1 1 2 2 2 0 Zinc ribbon domain zf_UBZ PF18439.1 EKX52110.1 - 0.66 9.6 1.8 3.4 7.3 0.1 2.1 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-NADH-PPase PF09297.11 EKX52110.1 - 1.3 8.7 10.8 3.3 7.5 0.4 2.3 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DEAD PF00270.29 EKX52111.1 - 4e-51 173.3 0.0 8.2e-50 169.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX52111.1 - 2.6e-32 111.4 0.1 5.4e-31 107.2 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX52111.1 - 2.5e-06 27.6 0.0 5.1e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EKX52111.1 - 0.003 16.8 0.0 0.0044 16.3 0.0 1.1 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase UTP25 PF06862.12 EKX52111.1 - 0.0079 15.0 0.0 0.057 12.2 0.0 1.9 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ABC_tran PF00005.27 EKX52112.1 - 3.5e-16 60.0 0.0 8.6e-16 58.7 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EKX52112.1 - 1.6e-12 47.9 2.0 5e-08 33.1 0.4 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EKX52112.1 - 6.5e-06 25.7 0.3 0.0038 16.7 0.1 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 EKX52112.1 - 0.088 12.5 1.1 0.4 10.4 0.1 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 EKX52112.1 - 0.12 12.0 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EKX52112.1 - 0.26 11.0 0.5 16 5.2 0.2 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain VWA_2 PF13519.6 EKX52113.1 - 5.6e-27 94.5 0.7 3.2e-26 92.1 0.0 2.6 3 1 1 4 4 4 1 von Willebrand factor type A domain Ssl1 PF04056.14 EKX52113.1 - 2e-07 31.0 0.3 5.5e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 Ssl1-like UIM PF02809.20 EKX52113.1 - 2.4e-07 30.2 21.3 0.0011 18.7 7.3 3.6 3 0 0 3 3 3 2 Ubiquitin interaction motif VWA PF00092.28 EKX52113.1 - 4.4e-05 23.8 0.9 0.00016 22.0 0.1 2.2 3 0 0 3 3 3 1 von Willebrand factor type A domain EpoR_lig-bind PF09067.10 EKX52114.1 - 0.029 14.6 0.6 0.075 13.3 0.2 1.9 2 0 0 2 2 2 0 Erythropoietin receptor, ligand binding DUF4548 PF15081.6 EKX52114.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4548) GP67 PF17634.2 EKX52114.1 - 0.39 11.1 16.0 1.3 9.5 16.0 1.9 1 0 0 1 1 1 0 Gene product 67 Zn_clus PF00172.18 EKX52115.1 - 0.00031 20.8 14.5 0.00053 20.1 14.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AIM24 PF01987.17 EKX52116.1 - 1.5e-26 93.5 0.2 3.5e-26 92.2 0.0 1.6 1 1 1 2 2 2 1 Mitochondrial biogenesis AIM24 AIM24 PF01987.17 EKX52117.1 - 4.8e-35 121.2 0.0 5.5e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF3806 PF12713.7 EKX52117.1 - 0.036 13.8 0.1 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3806) AIM24 PF01987.17 EKX52118.1 - 1.1e-36 126.6 0.2 1.3e-36 126.3 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Prot_ATP_ID_OB PF16450.5 EKX52118.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain NOG1_N PF17835.1 EKX52119.1 - 1.6e-52 177.7 0.3 1.6e-52 177.7 0.3 2.2 3 0 0 3 3 3 1 NOG1 N-terminal helical domain NOG1 PF06858.14 EKX52119.1 - 1.3e-26 92.1 0.8 4.9e-26 90.3 0.1 2.2 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 EKX52119.1 - 9.2e-25 86.4 1.0 9.2e-25 86.4 1.0 2.0 2 0 0 2 2 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 EKX52119.1 - 2.7e-18 66.1 0.0 8.2e-18 64.6 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EKX52119.1 - 1.1e-11 44.5 0.0 1.8e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.22 EKX52119.1 - 7.8e-05 22.3 0.1 0.0002 21.0 0.1 1.7 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 EKX52119.1 - 8e-05 22.6 1.6 0.29 11.0 0.0 3.5 3 1 0 3 3 3 2 RsgA GTPase AIG1 PF04548.16 EKX52119.1 - 0.0062 15.9 0.1 0.042 13.2 0.0 2.4 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.6 EKX52119.1 - 0.016 15.6 0.1 1.6 9.1 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain Dynamin_N PF00350.23 EKX52119.1 - 0.026 14.6 4.1 5.8 7.0 0.0 3.6 3 1 1 4 4 4 0 Dynamin family SRPRB PF09439.10 EKX52119.1 - 0.034 13.6 0.0 0.089 12.2 0.0 1.8 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EKX52119.1 - 0.16 12.2 1.0 3 8.1 0.0 3.3 4 0 0 4 4 4 0 AAA domain AAA_29 PF13555.6 EKX52119.1 - 0.22 11.3 0.0 24 4.8 0.0 2.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain TPT PF03151.16 EKX52120.1 - 9.6e-27 94.1 12.5 1.1e-26 93.9 12.5 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EKX52120.1 - 3.7e-09 36.9 20.2 8.8e-09 35.6 10.2 2.1 2 0 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 EKX52120.1 - 0.0016 17.8 8.7 0.0016 17.8 8.7 1.6 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport CorA PF01544.18 EKX52120.1 - 0.085 12.2 2.0 0.12 11.7 2.0 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF3995 PF13160.6 EKX52120.1 - 0.11 12.8 4.0 0.11 12.9 0.4 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3995) GTP_EFTU PF00009.27 EKX52121.1 - 1.1e-36 126.3 1.2 1.2e-34 119.5 1.2 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EKX52121.1 - 5.9e-26 90.6 0.5 1.8e-25 89.1 0.2 2.0 2 0 0 2 2 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 EKX52121.1 - 1.4e-10 41.3 0.0 3.7e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.15 EKX52121.1 - 8.3e-08 31.9 0.6 2.5e-07 30.4 0.2 2.0 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region SRPRB PF09439.10 EKX52121.1 - 2.5e-05 23.8 0.4 0.0002 20.8 0.0 2.5 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EKX52121.1 - 3.2e-05 23.5 0.0 0.00014 21.5 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EKX52121.1 - 3.7e-05 23.7 0.1 0.25 11.2 0.0 2.6 1 1 1 2 2 2 2 RsgA GTPase Arf PF00025.21 EKX52121.1 - 0.0001 21.8 0.0 0.00024 20.6 0.0 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EKX52121.1 - 0.0025 17.4 0.0 0.0087 15.7 0.0 1.9 2 0 0 2 2 2 1 Ras family MeaB PF03308.16 EKX52121.1 - 0.0026 16.8 0.4 0.012 14.6 0.2 2.1 1 1 1 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 EKX52121.1 - 0.0057 16.4 0.1 0.018 14.8 0.1 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 EKX52121.1 - 0.0059 16.8 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D4 PF14578.6 EKX52121.1 - 0.012 15.5 0.9 0.012 15.5 0.9 2.2 2 0 0 2 2 1 0 Elongation factor Tu domain 4 MMR_HSR1_Xtn PF16897.5 EKX52121.1 - 0.027 14.5 0.0 0.082 12.9 0.0 1.8 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 EKX52121.1 - 0.033 14.3 0.0 1.1 9.3 0.0 2.5 1 1 1 2 2 2 0 Dynamin family MnmE_helical PF12631.7 EKX52121.1 - 0.14 12.4 0.0 0.29 11.3 0.0 1.7 2 0 0 2 2 2 0 MnmE helical domain DENN PF02141.21 EKX52122.1 - 5.2e-46 156.9 0.7 9.7e-46 156.1 0.7 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 EKX52122.1 - 7.3e-10 39.5 0.2 1.8e-09 38.2 0.2 1.7 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 EKX52122.1 - 2.6e-05 24.1 0.2 4.8e-05 23.3 0.2 1.4 1 0 0 1 1 1 1 dDENN domain SPA PF08616.10 EKX52122.1 - 0.028 14.3 0.1 0.054 13.5 0.1 1.5 1 0 0 1 1 1 0 Stabilization of polarity axis DUF808 PF05661.12 EKX52122.1 - 0.2 10.6 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF808) Alpha-amyl_C2 PF07821.12 EKX52123.1 - 5.8e-15 55.3 1.8 1.2e-14 54.3 1.8 1.5 1 0 0 1 1 1 1 Alpha-amylase C-terminal beta-sheet domain Alpha-amylase PF00128.24 EKX52123.1 - 2.5e-11 43.7 0.0 3.8e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF3670 PF12419.8 EKX52123.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 SNF2 Helicase protein Flavodoxin_4 PF12682.7 EKX52123.1 - 0.12 12.1 0.1 0.29 10.8 0.0 1.6 2 0 0 2 2 2 0 Flavodoxin Pkinase PF00069.25 EKX52125.1 - 2e-35 122.4 0.0 4.4e-34 118.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX52125.1 - 1.7e-22 79.9 0.0 4.2e-22 78.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX52125.1 - 0.00017 20.5 0.0 0.00026 19.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX52125.1 - 0.0018 18.3 0.3 0.027 14.4 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EKX52125.1 - 0.11 11.8 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 EKX52125.1 - 0.13 11.1 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain CRT10 PF08728.10 EKX52125.1 - 0.2 9.8 0.0 0.23 9.6 0.0 1.1 1 0 0 1 1 1 0 CRT10 PDZ PF00595.24 EKX52126.1 - 2.4e-11 43.8 0.5 4.8e-11 42.9 0.5 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX52126.1 - 3.5e-09 36.4 0.1 7.4e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX52126.1 - 3.6e-08 33.6 0.1 7.6e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 PDZ domain UBA PF00627.31 EKX52126.1 - 1.3e-05 25.0 0.1 4.5e-05 23.3 0.1 1.8 2 0 0 2 2 2 1 UBA/TS-N domain PBD PF00786.28 EKX52126.1 - 5.3e-05 23.5 0.0 0.00015 22.0 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain U-box PF04564.15 EKX52126.1 - 0.00023 21.3 0.0 0.00085 19.5 0.0 2.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX52126.1 - 0.00081 19.2 0.0 0.003 17.3 0.0 1.9 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 EKX52126.1 - 0.0028 17.7 0.0 0.0083 16.2 0.0 1.8 2 0 0 2 2 1 1 Zinc-finger of nitric oxide synthase-interacting protein Fea1 PF07692.11 EKX52126.1 - 0.054 12.5 0.2 0.084 11.9 0.2 1.2 1 0 0 1 1 1 0 Low iron-inducible periplasmic protein Cep57_CLD_2 PF14197.6 EKX52126.1 - 2 8.5 15.4 0.25 11.4 7.5 2.8 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 UvrB PF12344.8 EKX52126.1 - 3.5 7.5 4.9 32 4.5 0.2 2.5 2 0 0 2 2 2 0 Ultra-violet resistance protein B RasGAP_C PF03836.15 EKX52126.1 - 5.6 7.1 14.2 0.12 12.6 3.0 3.0 3 1 1 4 4 4 0 RasGAP C-terminus Peptidase_M13_N PF05649.13 EKX52127.1 - 6.3e-70 236.8 0.1 8.1e-70 236.4 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 EKX52127.1 - 8.1e-62 208.5 0.0 1.7e-61 207.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M13 SIL1 PF16782.5 EKX52129.1 - 0.042 13.1 0.1 0.13 11.5 0.1 1.6 1 1 1 2 2 2 0 Nucleotide exchange factor SIL1 RAP PF08373.10 EKX52132.1 - 1.1e-12 47.8 0.6 3.4e-12 46.3 0.6 1.8 1 1 0 1 1 1 1 RAP domain DUF4604 PF15377.6 EKX52133.1 - 6 7.3 37.4 1.8 9.0 33.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) EF-hand_7 PF13499.6 EKX52134.1 - 1e-10 41.9 1.8 9.4e-05 22.8 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX52134.1 - 5.8e-08 31.7 2.0 0.0028 17.1 0.1 3.0 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX52134.1 - 3.4e-06 26.8 1.1 5.8e-05 22.8 0.2 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX52134.1 - 4.2e-06 26.2 2.3 0.072 13.1 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 EKX52134.1 - 0.00048 19.5 3.7 0.026 14.0 0.4 2.7 2 0 0 2 2 2 2 EF hand PRP9_N PF16958.5 EKX52134.1 - 0.011 15.8 0.1 0.011 15.8 0.1 2.4 3 0 0 3 3 3 0 Pre-mRNA-splicing factor PRP9 N-terminus Laminin_B PF00052.18 EKX52136.1 - 4.1e-11 42.9 0.0 6.1e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Laminin B (Domain IV) DUF3464 PF11947.8 EKX52137.1 - 1.2 8.9 3.6 0.31 10.8 0.3 1.6 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 zf-C3HC4_2 PF13923.6 EKX52137.1 - 2.7 7.9 10.4 5.4 6.9 10.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX52137.1 - 3.8 7.6 11.3 7.5 6.6 11.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain AAA_22 PF13401.6 EKX52139.1 - 0.00098 19.4 0.2 0.045 14.0 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EKX52139.1 - 0.0011 19.4 0.0 0.002 18.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EKX52139.1 - 0.024 14.7 0.2 0.14 12.2 0.0 2.3 2 1 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein Torsin PF06309.11 EKX52139.1 - 0.085 13.0 0.0 7.7 6.6 0.0 2.7 3 0 0 3 3 3 0 Torsin Aminotran_3 PF00202.21 EKX52140.1 - 2.6e-43 148.2 0.0 2.5e-33 115.3 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 EKX52140.1 - 3.1e-05 23.9 0.0 0.21 11.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain Yae1_N PF09811.9 EKX52141.1 - 1.1e-05 25.0 14.2 0.012 15.3 0.4 4.9 4 1 1 5 5 5 4 Essential protein Yae1, N terminal DUF5320 PF17253.2 EKX52141.1 - 0.4 11.8 14.4 2.9 9.0 3.4 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5320) PX PF00787.24 EKX52142.1 - 3.4e-15 56.0 0.6 7.4e-15 54.9 0.6 1.5 1 0 0 1 1 1 1 PX domain MH1 PF03165.16 EKX52142.1 - 1.8 8.8 4.5 6.6 7.0 0.2 2.7 3 0 0 3 3 3 0 MH1 domain Yae1_N PF09811.9 EKX52143.1 - 0.0013 18.4 14.2 0.47 10.2 0.1 4.9 4 1 1 5 5 5 3 Essential protein Yae1, N terminal DUF5320 PF17253.2 EKX52143.1 - 0.61 11.2 14.2 2.9 9.0 3.5 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5320) DUF1600 PF07667.11 EKX52143.1 - 2 8.6 7.8 3.7 7.8 7.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1600) Hydrolase_4 PF12146.8 EKX52145.1 - 2e-05 24.0 0.0 2.5e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EKX52145.1 - 0.00082 18.9 0.0 0.0016 18.0 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EKX52145.1 - 0.0013 18.4 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EKX52145.1 - 0.0034 17.3 0.0 0.0046 16.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 EKX52145.1 - 0.048 13.4 0.1 0.077 12.7 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein Say1_Mug180 PF10340.9 EKX52145.1 - 0.05 12.5 0.0 0.07 12.0 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase Pro_CA PF00484.19 EKX52145.1 - 0.055 13.8 0.0 0.08 13.2 0.0 1.2 1 0 0 1 1 1 0 Carbonic anhydrase Abhydrolase_6 PF12697.7 EKX52145.1 - 0.086 13.4 0.0 0.086 13.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1749 PF08538.10 EKX52145.1 - 0.13 11.3 0.1 0.35 9.9 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1749) LIDHydrolase PF10230.9 EKX52145.1 - 0.15 11.6 0.1 0.26 10.8 0.1 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF2974 PF11187.8 EKX52145.1 - 0.19 11.3 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Pho88 PF10032.9 EKX52146.1 - 2e-16 59.8 0.1 2.2e-16 59.7 0.1 1.1 1 0 0 1 1 1 1 Phosphate transport (Pho88) NdhM PF10664.9 EKX52146.1 - 0.14 12.5 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M PA PF02225.22 EKX52147.1 - 7e-13 48.4 0.2 1.1e-12 47.8 0.2 1.4 1 0 0 1 1 1 1 PA domain ZNRF_3_ecto PF18212.1 EKX52147.1 - 0.0054 16.7 0.0 0.0084 16.1 0.0 1.4 1 0 0 1 1 1 1 ZNRF-3 Ectodomain SIS PF01380.22 EKX52147.1 - 0.08 12.8 0.0 3.1 7.6 0.0 2.3 1 1 1 2 2 2 0 SIS domain Lipocalin_2 PF08212.12 EKX52148.1 - 0.022 14.7 0.0 3.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Lipocalin-like domain DnaJ_C PF01556.18 EKX52149.1 - 6.7e-38 130.1 0.1 9.5e-38 129.6 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EKX52149.1 - 7.5e-27 93.2 4.2 1.4e-26 92.4 4.2 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EKX52149.1 - 3.3e-14 53.0 19.1 6e-14 52.2 19.1 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EKX52149.1 - 9.8e-06 25.5 10.8 0.0022 17.9 2.5 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EKX52149.1 - 3.9e-05 23.6 9.5 0.025 14.6 2.7 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 EKX52149.1 - 0.064 13.6 10.0 0.74 10.2 1.5 3.5 1 1 2 3 3 3 0 Restriction alleviation protein Lar DZR PF12773.7 EKX52149.1 - 0.16 12.1 12.6 1.8 8.7 1.4 2.2 1 1 2 3 3 3 0 Double zinc ribbon TackOD1 PF18551.1 EKX52149.1 - 0.38 10.4 7.3 0.22 11.2 1.2 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 zf-C3HC4_3 PF13920.6 EKX52149.1 - 0.76 9.7 7.9 0.31 10.9 1.5 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.6 EKX52149.1 - 1.1 8.7 10.3 28 4.3 0.1 4.2 4 0 0 4 4 4 0 zinc-ribbon domain RHH_6 PF16762.5 EKX52150.1 - 0.055 14.1 0.1 0.17 12.5 0.1 1.8 1 0 0 1 1 1 0 Ribbon-helix-helix domain ISP1_C PF18161.1 EKX52150.1 - 0.095 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 ISP1 C-terminal Herpes_UL25 PF01499.16 EKX52150.1 - 0.49 8.9 7.4 0.79 8.2 7.1 1.6 1 1 0 1 1 1 0 Herpesvirus UL25 family EF-hand_7 PF13499.6 EKX52151.1 - 1.2e-05 25.7 6.9 0.00073 19.9 0.9 3.5 3 1 1 4 4 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX52151.1 - 0.00034 20.0 2.5 0.0023 17.3 0.2 3.6 4 0 0 4 4 3 1 EF hand EF-hand_8 PF13833.6 EKX52151.1 - 0.00056 19.7 0.2 0.017 15.0 0.2 2.8 2 0 0 2 2 2 1 EF-hand domain pair Fez1 PF06818.15 EKX52151.1 - 0.0015 19.0 14.5 0.0015 19.0 14.5 2.3 1 1 1 2 2 2 1 Fez1 PilJ PF13675.6 EKX52151.1 - 0.0035 17.4 4.8 0.12 12.4 0.3 3.1 1 1 2 3 3 3 1 Type IV pili methyl-accepting chemotaxis transducer N-term Golgin_A5 PF09787.9 EKX52151.1 - 0.0059 16.1 10.8 0.012 15.0 10.8 1.6 1 0 0 1 1 1 1 Golgin subfamily A member 5 EF-hand_6 PF13405.6 EKX52151.1 - 0.0076 16.1 2.4 0.052 13.5 0.2 3.6 3 0 0 3 3 2 1 EF-hand domain DUF4407 PF14362.6 EKX52151.1 - 0.01 15.2 11.2 0.019 14.3 11.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 EKX52151.1 - 0.013 14.6 11.8 0.023 13.8 11.8 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OSCP PF00213.18 EKX52151.1 - 0.014 15.6 4.0 0.041 14.0 4.0 1.8 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit PKcGMP_CC PF16808.5 EKX52151.1 - 0.072 12.9 9.3 2.2 8.2 1.5 3.9 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF1664 PF07889.12 EKX52151.1 - 0.086 12.9 11.8 0.095 12.7 5.7 2.8 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 EKX52151.1 - 0.23 10.3 25.4 0.34 9.8 23.0 2.2 2 1 0 2 2 2 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 EKX52151.1 - 0.31 10.6 9.0 0.59 9.7 9.0 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit BST2 PF16716.5 EKX52151.1 - 0.32 11.6 20.6 0.14 12.8 13.5 2.9 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DUF745 PF05335.13 EKX52151.1 - 0.33 10.7 10.7 0.87 9.3 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF745) PEARLI-4 PF05278.12 EKX52151.1 - 0.6 9.7 11.4 2.1 7.9 11.4 1.9 1 1 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) LOH1CR12 PF10158.9 EKX52151.1 - 0.6 10.1 5.6 0.68 10.0 0.3 3.0 4 0 0 4 4 2 0 Tumour suppressor protein Seryl_tRNA_N PF02403.22 EKX52151.1 - 0.86 9.9 21.9 1.7 8.9 11.8 3.5 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Baculo_PEP_C PF04513.12 EKX52151.1 - 0.99 9.4 6.0 5.3 7.1 0.5 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Wtap PF17098.5 EKX52151.1 - 1.2 9.1 14.3 1.1 9.1 4.5 2.5 1 1 1 2 2 2 0 WTAP/Mum2p family EzrA PF06160.12 EKX52151.1 - 1.2 7.2 14.5 2.2 6.4 14.5 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.9 EKX52151.1 - 1.8 8.6 26.8 1.6 8.7 14.5 2.9 2 1 1 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HrpB7 PF09486.10 EKX52151.1 - 2.1 8.7 12.2 9.8 6.5 12.2 2.1 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) LMBR1 PF04791.16 EKX52151.1 - 2.1 7.1 6.1 3.4 6.5 6.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4201 PF13870.6 EKX52151.1 - 2.2 8.0 18.9 0.56 9.9 11.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) ATG16 PF08614.11 EKX52151.1 - 2.9 8.1 22.5 35 4.6 21.9 2.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 EKX52151.1 - 4.1 7.9 7.0 5 7.6 2.9 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.12 EKX52151.1 - 4.2 7.4 22.2 18 5.4 22.2 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DLP_helical PF18709.1 EKX52151.1 - 4.3 6.4 12.6 32 3.6 12.7 2.0 1 1 0 1 1 1 0 Dynamin-like helical domain KxDL PF10241.9 EKX52151.1 - 4.4 7.6 12.3 6.8 7.0 6.5 3.0 1 1 2 3 3 3 0 Uncharacterized conserved protein Lebercilin PF15619.6 EKX52151.1 - 4.7 6.8 22.8 12 5.5 22.8 1.6 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease WXG100 PF06013.12 EKX52151.1 - 4.8 7.5 6.8 18 5.7 0.2 3.3 2 1 1 3 3 3 0 Proteins of 100 residues with WXG ADIP PF11559.8 EKX52151.1 - 6 6.9 17.9 8.4 6.5 14.2 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding KLRAQ PF10205.9 EKX52151.1 - 6.3 7.1 12.6 5.8 7.2 10.1 2.2 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein GAS PF13851.6 EKX52151.1 - 6.3 6.1 24.3 0.72 9.2 9.4 2.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMPIT PF07851.13 EKX52151.1 - 9.2 5.4 11.3 3.3 6.9 7.7 1.9 1 1 1 2 2 2 0 TMPIT-like protein EF-hand_7 PF13499.6 EKX52153.1 - 0.00014 22.3 4.9 0.0031 17.9 0.7 3.3 3 1 1 4 4 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX52153.1 - 0.0013 18.1 2.4 0.0086 15.6 0.2 3.5 4 0 0 4 4 3 1 EF hand Fez1 PF06818.15 EKX52153.1 - 0.0014 19.1 13.9 0.0014 19.1 13.9 2.3 1 1 1 2 2 2 1 Fez1 PilJ PF13675.6 EKX52153.1 - 0.0014 18.6 6.2 0.015 15.3 0.6 3.0 1 1 2 3 3 3 1 Type IV pili methyl-accepting chemotaxis transducer N-term EF-hand_8 PF13833.6 EKX52153.1 - 0.0015 18.3 0.2 0.055 13.3 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain pair DUF4407 PF14362.6 EKX52153.1 - 0.0026 17.2 10.8 0.0026 17.2 10.8 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) Golgin_A5 PF09787.9 EKX52153.1 - 0.0079 15.7 11.4 0.016 14.7 11.4 1.5 1 0 0 1 1 1 1 Golgin subfamily A member 5 Atg14 PF10186.9 EKX52153.1 - 0.015 14.4 12.3 0.028 13.5 12.3 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 EF-hand_6 PF13405.6 EKX52153.1 - 0.022 14.6 1.5 0.29 11.2 0.2 3.6 3 0 0 3 3 2 0 EF-hand domain Spc7 PF08317.11 EKX52153.1 - 0.027 13.4 22.9 0.14 11.0 22.9 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein PKcGMP_CC PF16808.5 EKX52153.1 - 0.04 13.8 10.4 2.1 8.3 0.8 4.0 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase EF-hand_4 PF12763.7 EKX52153.1 - 0.074 13.0 0.1 0.21 11.5 0.1 1.7 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand DUF1664 PF07889.12 EKX52153.1 - 0.088 12.9 9.4 0.13 12.3 4.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BST2 PF16716.5 EKX52153.1 - 0.1 13.2 20.0 0.082 13.5 13.2 2.7 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 CENP-F_leu_zip PF10473.9 EKX52153.1 - 0.12 12.4 23.1 2.4 8.2 16.1 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LOH1CR12 PF10158.9 EKX52153.1 - 0.15 12.1 3.5 0.55 10.3 0.5 2.6 3 0 0 3 3 2 0 Tumour suppressor protein PEARLI-4 PF05278.12 EKX52153.1 - 0.27 10.8 9.8 0.13 11.8 7.1 1.8 1 1 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Pox_A_type_inc PF04508.12 EKX52153.1 - 0.3 11.0 3.2 0.89 9.5 0.1 3.1 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat OSCP PF00213.18 EKX52153.1 - 0.48 10.5 7.5 0.13 12.4 4.1 1.8 2 0 0 2 2 1 0 ATP synthase delta (OSCP) subunit DLP_helical PF18709.1 EKX52153.1 - 0.7 9.0 11.6 2.4 7.3 11.6 1.7 1 1 0 1 1 1 0 Dynamin-like helical domain Exonuc_VII_L PF02601.15 EKX52153.1 - 0.7 9.4 9.9 1.4 8.5 9.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit TPR_MLP1_2 PF07926.12 EKX52153.1 - 0.75 9.9 20.6 2.2 8.4 20.6 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein HrpB7 PF09486.10 EKX52153.1 - 0.82 10.0 12.0 2.9 8.2 12.0 1.9 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) ATG16 PF08614.11 EKX52153.1 - 0.94 9.7 23.1 9.9 6.3 23.1 2.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF745 PF05335.13 EKX52153.1 - 1 9.1 12.8 0.38 10.4 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) FapA PF03961.13 EKX52153.1 - 1.1 7.7 10.7 2.5 6.6 10.7 1.5 1 0 0 1 1 1 0 Flagellar Assembly Protein A Baculo_PEP_C PF04513.12 EKX52153.1 - 1.3 9.1 5.4 7.4 6.6 0.3 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Seryl_tRNA_N PF02403.22 EKX52153.1 - 2.5 8.4 21.1 5.4 7.3 10.5 3.5 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Nup88 PF10168.9 EKX52153.1 - 2.6 5.7 13.4 4.1 5.1 13.4 1.2 1 0 0 1 1 1 0 Nuclear pore component TMF_TATA_bd PF12325.8 EKX52153.1 - 2.9 8.1 14.9 0.49 10.6 6.8 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4201 PF13870.6 EKX52153.1 - 3.3 7.4 19.0 0.71 9.6 10.9 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF724 PF05266.14 EKX52153.1 - 5 6.9 18.4 43 3.9 15.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) CCDC-167 PF15188.6 EKX52153.1 - 5 7.5 16.4 2.6 8.4 7.9 3.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 SlyX PF04102.12 EKX52153.1 - 5.4 7.7 12.1 1.5 9.5 3.3 3.0 1 1 1 2 2 2 0 SlyX KxDL PF10241.9 EKX52153.1 - 5.4 7.4 12.2 9.5 6.6 6.1 3.0 1 1 2 3 3 3 0 Uncharacterized conserved protein EzrA PF06160.12 EKX52153.1 - 5.5 5.0 17.2 1.4 7.0 13.5 1.8 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Sec8_exocyst PF04048.14 EKX52153.1 - 6.5 6.6 8.6 21 5.0 0.2 2.9 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain NuiA PF07924.11 EKX52153.1 - 9 6.7 7.4 0.45 10.9 0.7 2.1 2 0 0 2 2 1 0 Nuclease A inhibitor-like protein FlaC_arch PF05377.11 EKX52153.1 - 9.5 6.7 7.8 4 7.9 2.7 2.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) CS PF04969.16 EKX52154.1 - 5.1e-06 27.4 0.0 9.3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 CS domain Spore_coat_CotO PF14153.6 EKX52154.1 - 0.017 15.0 7.2 0.028 14.4 7.2 1.3 1 0 0 1 1 1 0 Spore coat protein CotO SUIM_assoc PF16619.5 EKX52154.1 - 0.1 12.7 11.7 0.23 11.6 11.7 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TEX19 PF15553.6 EKX52154.1 - 0.81 9.6 5.6 1.4 8.9 5.6 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 Spt20 PF12090.8 EKX52154.1 - 1.2 8.7 12.0 1.9 8.0 12.0 1.3 1 0 0 1 1 1 0 Spt20 family PTPRCAP PF15713.5 EKX52154.1 - 2.4 8.5 13.1 4.5 7.6 13.1 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Roughex PF06020.11 EKX52154.1 - 5.2 6.1 9.2 7.8 5.5 9.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Presenilin PF01080.17 EKX52154.1 - 6.5 5.4 7.5 5.4 5.7 6.4 1.4 2 0 0 2 2 2 0 Presenilin UPF0560 PF10577.9 EKX52154.1 - 7.4 4.9 11.0 9.9 4.5 11.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TPR_1 PF00515.28 EKX52155.1 - 4.9e-28 95.8 1.9 2e-06 27.3 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 EKX52155.1 - 4.7e-22 77.4 2.8 6.2e-06 25.8 0.0 5.5 3 1 2 5 5 5 4 TPR repeat TPR_2 PF07719.17 EKX52155.1 - 6.6e-21 72.7 2.5 0.0004 20.3 0.0 6.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EKX52155.1 - 4.8e-20 70.0 1.1 0.00015 21.7 0.1 5.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 EKX52155.1 - 3.5e-16 59.2 0.6 2.8e-05 24.3 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 EKX52155.1 - 2.5e-15 55.7 2.2 4.7e-05 23.5 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX52155.1 - 2e-14 52.5 0.6 0.017 15.1 0.0 5.1 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 EKX52155.1 - 4.4e-13 48.9 1.4 0.034 15.0 0.0 5.9 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX52155.1 - 7.1e-12 45.8 6.8 6.3e-05 23.5 0.0 4.8 4 1 2 6 6 4 3 Tetratricopeptide repeat Methyltransf_31 PF13847.6 EKX52155.1 - 1.2e-11 44.7 0.0 3.8e-11 43.0 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX52155.1 - 5.7e-11 42.5 0.0 9.9e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX52155.1 - 2.8e-10 40.8 0.0 1.4e-09 38.6 0.0 2.3 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX52155.1 - 6.3e-10 39.6 0.0 1.4e-08 35.3 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain TPR_19 PF14559.6 EKX52155.1 - 7.8e-10 39.1 3.6 0.0082 16.6 0.1 4.9 3 1 1 4 4 4 2 Tetratricopeptide repeat Methyltransf_25 PF13649.6 EKX52155.1 - 1.4e-09 38.6 0.1 1.2e-08 35.6 0.0 2.7 3 1 1 4 4 2 1 Methyltransferase domain TPR_10 PF13374.6 EKX52155.1 - 2e-09 37.0 0.5 0.21 11.5 0.1 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX52155.1 - 1.1e-06 28.7 0.0 0.041 14.0 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX52155.1 - 1.7e-05 25.2 0.5 0.34 11.6 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat Methyltransf_32 PF13679.6 EKX52155.1 - 0.00011 22.2 0.0 0.00033 20.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EKX52155.1 - 0.00014 21.2 0.1 0.00023 20.6 0.1 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase EST1_DNA_bind PF10373.9 EKX52155.1 - 0.00018 21.1 1.8 0.024 14.1 0.5 2.5 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain ANAPC3 PF12895.7 EKX52155.1 - 0.00023 21.3 0.5 0.058 13.6 0.0 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Methyltransf_16 PF10294.9 EKX52155.1 - 0.00027 20.7 0.0 0.00055 19.7 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EKX52155.1 - 0.0016 18.0 0.0 0.0038 16.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain TPR_20 PF14561.6 EKX52155.1 - 0.0042 17.4 6.0 8.5 6.8 0.0 3.9 3 1 1 4 4 3 0 Tetratricopeptide repeat Sel1 PF08238.12 EKX52155.1 - 0.0066 17.1 0.0 3.5 8.4 0.0 3.3 2 1 0 2 2 2 1 Sel1 repeat HemY_N PF07219.13 EKX52155.1 - 0.0077 16.4 1.8 0.036 14.3 0.0 2.7 2 1 0 2 2 2 1 HemY protein N-terminus NodS PF05401.11 EKX52155.1 - 0.0079 15.8 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 EKX52155.1 - 0.0095 15.3 0.0 0.02 14.2 0.0 1.6 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 EKX52155.1 - 0.015 14.9 0.0 0.037 13.6 0.0 1.6 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MIT PF04212.18 EKX52155.1 - 0.039 14.0 4.8 32 4.7 0.0 5.0 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain PrmA PF06325.13 EKX52155.1 - 0.045 13.1 0.0 0.096 12.1 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) AdoMet_MTase PF07757.13 EKX52155.1 - 0.094 13.1 0.4 1.6 9.1 0.1 2.6 1 1 1 2 2 2 0 Predicted AdoMet-dependent methyltransferase DUF268 PF03269.14 EKX52156.1 - 9.4e-32 110.3 0.0 1.9e-31 109.3 0.0 1.4 1 0 0 1 1 1 1 Caenorhabditis protein of unknown function, DUF268 WW PF00397.26 EKX52157.1 - 7.7e-06 25.9 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 WW domain MazG PF03819.17 EKX52158.1 - 1e-07 32.0 0.0 4.4e-07 30.0 0.0 2.1 1 1 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain JAKMIP_CC3 PF16034.5 EKX52158.1 - 0.028 14.4 1.4 0.065 13.2 1.4 1.6 1 0 0 1 1 1 0 JAKMIP CC3 domain FPP PF05911.11 EKX52158.1 - 0.084 11.0 1.6 0.1 10.7 1.6 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Macoilin PF09726.9 EKX52158.1 - 0.11 11.1 0.4 0.14 10.7 0.4 1.1 1 0 0 1 1 1 0 Macoilin family Uso1_p115_C PF04871.13 EKX52158.1 - 0.13 12.6 3.2 1.9 8.9 3.2 2.2 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region TSNAXIP1_N PF15739.5 EKX52158.1 - 0.15 12.5 1.4 0.25 11.7 0.8 1.6 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus DUF4140 PF13600.6 EKX52158.1 - 0.2 12.1 0.5 0.61 10.6 0.2 2.0 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) FlaC_arch PF05377.11 EKX52158.1 - 0.2 12.0 2.8 0.2 12.1 1.1 2.0 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) HTH_Tnp_Tc3_1 PF11427.8 EKX52158.1 - 0.24 11.3 1.0 13 5.7 0.1 2.6 2 0 0 2 2 2 0 Tc3 transposase DUF812 PF05667.11 EKX52158.1 - 0.24 10.2 1.0 0.34 9.8 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) PI3K_P85_iSH2 PF16454.5 EKX52158.1 - 0.33 10.6 4.1 0.11 12.1 1.6 1.5 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Tropomyosin PF00261.20 EKX52158.1 - 0.33 10.3 5.1 0.084 12.2 2.0 1.5 2 0 0 2 2 2 0 Tropomyosin Spc7 PF08317.11 EKX52158.1 - 0.34 9.7 2.5 0.21 10.4 0.7 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein zf-C2H2_jaz PF12171.8 EKX52162.1 - 1.8e-06 28.1 0.0 4e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding LRR_6 PF13516.6 EKX52162.1 - 5.3e-05 22.9 13.5 7.6 6.9 0.3 7.2 7 0 0 7 7 7 1 Leucine Rich repeat zf-met PF12874.7 EKX52162.1 - 0.00037 20.8 0.0 0.001 19.4 0.0 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EKX52162.1 - 0.013 15.9 0.1 0.04 14.3 0.1 1.8 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) LRR_4 PF12799.7 EKX52162.1 - 0.013 15.9 5.4 0.039 14.4 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) NFACT-R_1 PF05670.13 EKX52162.1 - 0.065 13.9 0.1 0.44 11.2 0.0 2.3 2 0 0 2 2 2 0 NFACT protein RNA binding domain zf-C2H2_4 PF13894.6 EKX52162.1 - 0.14 13.1 0.1 0.73 10.8 0.1 2.4 1 0 0 1 1 1 0 C2H2-type zinc finger RFamide_26RFa PF11109.8 EKX52162.1 - 0.29 11.6 4.2 0.97 9.9 1.3 3.0 3 0 0 3 3 3 0 Orexigenic neuropeptide Qrfp/P518 EF-hand_1 PF00036.32 EKX52163.1 - 3.1e-07 29.4 0.3 0.015 14.8 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EKX52163.1 - 3.9e-06 26.1 0.4 0.075 12.6 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX52163.1 - 1.1e-05 25.7 0.1 2.6e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX52163.1 - 5.1e-05 22.9 0.9 0.012 15.5 0.0 2.7 2 1 1 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 EKX52163.1 - 5.4e-05 23.0 0.1 0.015 15.2 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair FAM193_C PF15914.5 EKX52164.1 - 0.067 12.9 0.1 0.2 11.4 0.1 1.8 1 0 0 1 1 1 0 FAM193 family C-terminal BLOC1_2 PF10046.9 EKX52164.1 - 0.89 9.9 20.2 0.14 12.5 1.0 4.9 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ax_dynein_light PF10211.9 EKX52165.1 - 1.6e-67 227.1 8.5 2.6e-67 226.4 8.5 1.3 1 0 0 1 1 1 1 Axonemal dynein light chain APG6_N PF17675.1 EKX52165.1 - 0.00035 21.1 7.7 0.00035 21.1 7.7 1.8 2 0 0 2 2 2 1 Apg6 coiled-coil region Takusan PF04822.13 EKX52165.1 - 0.0092 15.8 5.2 0.022 14.7 5.2 1.6 1 0 0 1 1 1 1 Takusan Cor1 PF04803.12 EKX52165.1 - 0.05 13.8 8.3 0.15 12.3 8.4 1.7 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region SLX9 PF15341.6 EKX52165.1 - 0.14 12.5 9.0 0.15 12.4 4.0 2.1 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 ApoO PF09769.9 EKX52165.1 - 0.27 11.2 1.9 0.37 10.7 1.2 1.7 2 0 0 2 2 2 0 Apolipoprotein O PCRF PF03462.18 EKX52165.1 - 0.41 10.5 6.2 0.14 12.0 3.4 1.6 2 0 0 2 2 2 0 PCRF domain TEX13 PF15186.6 EKX52165.1 - 0.47 10.1 7.0 0.9 9.2 7.0 1.5 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family PCEMA1 PF07418.11 EKX52165.1 - 1.9 7.9 7.8 0.21 11.1 3.7 1.4 2 0 0 2 2 2 0 Acidic phosphoprotein precursor PCEMA1 AAA_11 PF13086.6 EKX52165.1 - 5.1 6.8 10.0 2.1 8.1 7.8 1.4 1 1 0 1 1 1 0 AAA domain Peptidase_S41 PF03572.18 EKX52166.1 - 3.3e-29 101.6 0.4 1.3e-28 99.7 0.4 1.9 1 1 0 1 1 1 1 Peptidase family S41 Tricorn_C1 PF14684.6 EKX52166.1 - 1.4e-06 28.2 0.1 2.4e-06 27.5 0.1 1.3 1 0 0 1 1 1 1 Tricorn protease C1 domain PDZ_2 PF13180.6 EKX52166.1 - 9.4e-06 25.9 2.5 6.2e-05 23.2 1.2 2.6 2 1 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EKX52166.1 - 0.00031 20.5 0.1 0.019 14.8 0.0 2.7 3 0 0 3 3 3 1 PDZ domain PDZ PF00595.24 EKX52166.1 - 0.14 12.5 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 PDZ domain SLAC1 PF03595.17 EKX52168.1 - 4.8e-15 55.6 34.4 5.8e-15 55.4 34.4 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel Transmemb_17 PF09799.9 EKX52169.1 - 2.3e-27 95.7 12.2 3e-27 95.3 12.2 1.1 1 0 0 1 1 1 1 Predicted membrane protein Asp_Arg_Hydrox PF05118.15 EKX52170.1 - 2.1e-43 147.9 0.6 4.8e-43 146.7 0.1 1.8 2 0 0 2 2 2 1 Aspartyl/Asparaginyl beta-hydroxylase SGL PF08450.12 EKX52170.1 - 4.9e-14 52.5 0.0 1.6e-13 50.8 0.0 1.7 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 EKX52170.1 - 0.001 19.1 0.0 0.0037 17.3 0.0 2.0 2 1 0 2 2 2 1 Strictosidine synthase NHL PF01436.21 EKX52170.1 - 0.0028 17.6 0.1 2.3 8.4 0.0 4.1 5 0 0 5 5 5 1 NHL repeat Arylesterase PF01731.20 EKX52170.1 - 0.003 17.7 0.0 0.024 14.8 0.0 2.2 2 0 0 2 2 2 1 Arylesterase Lactonase PF10282.9 EKX52170.1 - 0.039 13.2 0.0 0.67 9.1 0.0 2.1 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller SBBP PF06739.11 EKX52170.1 - 0.052 13.5 0.0 78 3.4 0.0 4.2 5 0 0 5 5 5 0 Beta-propeller repeat Peptidase_C48 PF02902.19 EKX52171.1 - 1.1e-08 35.3 0.1 4.8e-08 33.1 0.1 2.1 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SWIM PF04434.17 EKX52171.1 - 1.5e-08 34.1 0.6 7.6e-07 28.7 0.1 2.6 2 0 0 2 2 2 1 SWIM zinc finger Ribosomal_60s PF00428.19 EKX52171.1 - 0.012 16.2 7.1 0.1 13.2 7.2 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein zf-CCHC_4 PF14392.6 EKX52171.1 - 0.025 14.3 2.0 0.1 12.4 1.1 2.6 3 0 0 3 3 3 0 Zinc knuckle zf-ribbon_3 PF13248.6 EKX52171.1 - 0.072 12.5 3.2 6.2 6.4 1.0 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-CCHC_6 PF15288.6 EKX52171.1 - 0.15 11.9 2.3 0.53 10.2 2.3 2.0 1 0 0 1 1 1 0 Zinc knuckle Paf1 PF03985.13 EKX52171.1 - 3.7 6.5 15.7 1.2 8.1 7.4 2.1 2 0 0 2 2 2 0 Paf1 Beta_helix PF13229.6 EKX52172.1 - 2e-35 122.0 44.3 2.8e-11 43.5 3.5 5.1 1 1 3 5 5 5 5 Right handed beta helix region NosD PF05048.13 EKX52172.1 - 3.6e-15 55.9 25.3 6.6e-07 28.8 2.3 4.5 1 1 3 4 4 4 4 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.7 EKX52172.1 - 1.1e-05 25.5 15.4 2.1e-05 24.5 0.9 3.9 2 1 2 4 4 4 2 Pectate lyase superfamily protein Gas_vesicle_C PF01304.17 EKX52172.1 - 0.23 11.5 0.4 0.41 10.7 0.4 1.4 1 0 0 1 1 1 0 Gas vesicles protein GVPc repeated domain LapD_MoxY_N PF16448.5 EKX52173.1 - 0.081 12.8 0.3 0.13 12.1 0.3 1.2 1 0 0 1 1 1 0 LapD/MoxY periplasmic domain LAX PF15681.5 EKX52173.1 - 0.1 11.4 2.0 0.14 10.9 2.0 1.2 1 0 0 1 1 1 0 Lymphocyte activation family X Glyco_transf_49 PF13896.6 EKX52174.1 - 1.1e-39 136.8 0.2 5.4e-33 114.7 0.2 2.2 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan ASCH PF04266.14 EKX52175.1 - 7e-15 55.5 0.0 2e-14 54.1 0.0 1.8 1 0 0 1 1 1 1 ASCH domain zf-C2HC5 PF06221.13 EKX52175.1 - 0.00011 22.1 0.7 0.00023 21.1 0.7 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type HypA PF01155.19 EKX52175.1 - 0.094 12.7 0.8 0.19 11.8 0.8 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Raftlin PF15250.6 EKX52175.1 - 1.8 7.2 7.1 3.5 6.3 7.1 1.5 1 0 0 1 1 1 0 Raftlin SMC_N PF02463.19 EKX52177.1 - 3.3e-55 186.9 81.2 5.3e-54 183.0 81.2 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EKX52177.1 - 6.6e-22 78.0 0.4 3.1e-21 75.8 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EKX52177.1 - 7.1e-10 39.2 12.5 5.3e-05 23.2 0.0 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EKX52177.1 - 2.9e-09 37.1 21.9 2.9e-09 37.1 21.9 4.3 2 2 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 EKX52177.1 - 2.8e-06 27.0 0.0 5.9e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain HTH_46 PF15977.5 EKX52177.1 - 0.061 13.4 2.3 0.8 9.8 0.1 3.4 3 0 0 3 3 3 0 Winged helix-turn-helix DNA binding Mce4_CUP1 PF11887.8 EKX52177.1 - 0.16 11.4 4.9 0.26 10.7 0.5 3.3 3 0 0 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative ABC_tran PF00005.27 EKX52177.1 - 0.41 11.2 0.0 0.41 11.2 0.0 7.2 3 2 0 3 3 3 0 ABC transporter PHO4 PF01384.20 EKX52178.1 - 0.12 11.5 13.8 0.15 11.0 13.8 1.2 1 0 0 1 1 1 0 Phosphate transporter family DUF4131 PF13567.6 EKX52178.1 - 0.33 10.6 1.4 0.33 10.6 0.2 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Gaa1 PF04114.14 EKX52178.1 - 0.84 8.6 16.2 0.97 8.4 16.2 1.0 1 0 0 1 1 1 0 Gaa1-like, GPI transamidase component CitMHS PF03600.16 EKX52178.1 - 3.8 6.6 28.0 4.6 6.3 28.0 1.1 1 0 0 1 1 1 0 Citrate transporter SpoIIM PF01944.17 EKX52178.1 - 7.1 6.7 17.4 9.8 6.2 17.4 1.1 1 0 0 1 1 1 0 Stage II sporulation protein M PLAC8 PF04749.17 EKX52178.1 - 8 7.5 10.3 11 7.0 10.3 1.4 1 0 0 1 1 1 0 PLAC8 family GPDPase_memb PF10110.9 EKX52178.1 - 9.5 4.9 26.9 12 4.5 26.9 1.1 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase UPF0182 PF03699.13 EKX52178.1 - 9.8 4.2 18.1 15 3.6 18.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Pho86 PF11124.8 EKX52178.1 - 10 5.5 15.4 12 5.3 15.4 1.2 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 SNase PF00565.17 EKX52179.1 - 5.9e-14 52.5 0.0 1e-13 51.7 0.0 1.4 1 0 0 1 1 1 1 Staphylococcal nuclease homologue FA_hydroxylase PF04116.13 EKX52180.1 - 2e-18 67.0 25.6 2e-18 67.0 25.6 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Rubis-subs-bind PF09273.11 EKX52183.1 - 3.4e-22 79.5 0.1 6.7e-22 78.6 0.0 1.5 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding KH_1 PF00013.29 EKX52185.1 - 8e-13 48.0 0.1 3.2e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 KH domain STAR_dimer PF16544.5 EKX52185.1 - 0.00078 19.0 2.8 0.0041 16.7 1.0 2.4 2 0 0 2 2 2 1 Homodimerisation region of STAR domain protein COPIIcoated_ERV PF07970.12 EKX52186.1 - 4.3e-78 262.2 0.2 6.6e-78 261.6 0.2 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EKX52186.1 - 5e-31 106.9 0.4 9.6e-31 106.0 0.4 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) H_lectin PF09458.10 EKX52186.1 - 0.095 12.9 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 H-type lectin domain IU_nuc_hydro PF01156.19 EKX52187.1 - 1.7e-35 123.1 0.0 2e-35 122.9 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF3367 PF11847.8 EKX52188.1 - 0.02 12.8 0.1 0.023 12.6 0.1 1.0 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase DUF3933 PF13069.6 EKX52189.1 - 0.074 12.9 0.4 0.11 12.4 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3933) Pkinase PF00069.25 EKX52190.1 - 3.3e-54 184.0 0.4 1.9e-53 181.6 0.4 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX52190.1 - 1.3e-30 106.6 0.1 2e-30 105.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EKX52190.1 - 9.7e-10 38.7 0.0 2.4e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 EKX52190.1 - 1.5e-08 34.4 0.0 4.9e-08 32.6 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EKX52190.1 - 1.2e-07 30.9 0.0 1.6e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EKX52190.1 - 0.00013 21.5 0.0 0.00035 20.1 0.0 1.6 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Yop-YscD_cpl PF16697.5 EKX52190.1 - 0.00061 20.1 0.0 0.042 14.2 0.0 2.5 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 EKX52190.1 - 0.0038 16.6 0.0 0.0066 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family cNMP_binding PF00027.29 EKX52191.1 - 2.1e-25 88.6 0.1 3.2e-14 52.8 0.0 2.1 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 EKX52191.1 - 0.0034 17.1 0.0 0.12 12.1 0.0 2.5 3 0 0 3 3 3 1 Cupin domain Cupin_3 PF05899.12 EKX52191.1 - 0.0078 15.9 0.1 0.048 13.4 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF861) zf-AN1 PF01428.16 EKX52192.1 - 4.2e-23 81.2 30.9 4.7e-13 49.1 10.1 2.7 3 0 0 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 EKX52192.1 - 1.4e-05 25.3 16.6 0.00025 21.3 4.2 2.4 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain IBR PF01485.21 EKX52192.1 - 0.28 11.4 25.8 1.5 9.1 7.3 3.0 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf_C2HC_14 PF18574.1 EKX52192.1 - 5.4 6.9 15.8 0.45 10.3 0.9 3.8 5 0 0 5 5 5 0 C2HC Zing finger domain Lactamase_B_3 PF13483.6 EKX52193.1 - 2e-23 83.1 0.0 2.9e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain SF3b1 PF08920.10 EKX52193.1 - 0.13 12.8 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 Splicing factor 3B subunit 1 WD40 PF00400.32 EKX52194.1 - 5e-54 179.1 24.3 4.9e-09 36.7 0.1 11.0 11 0 0 11 11 11 9 WD domain, G-beta repeat Utp13 PF08625.11 EKX52194.1 - 5.5e-29 100.9 0.7 1.1e-28 99.9 0.7 1.6 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 EKX52194.1 - 1.8e-15 57.0 6.9 0.049 13.9 0.0 8.9 4 3 6 10 10 10 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EKX52194.1 - 0.00025 20.5 0.0 0.59 9.4 0.0 2.9 3 0 0 3 3 3 2 WD40-like domain PALB2_WD40 PF16756.5 EKX52194.1 - 0.0045 16.0 1.6 0.039 12.9 0.5 2.8 2 0 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 EKX52194.1 - 0.0072 15.0 9.2 1.6 7.3 0.1 5.8 3 3 2 6 6 6 2 Nucleoporin Nup120/160 Mcl1_mid PF12341.8 EKX52194.1 - 0.035 13.5 0.3 0.31 10.3 0.3 2.4 1 1 0 1 1 1 0 Minichromosome loss protein, Mcl1, middle region Nucleoporin_N PF08801.11 EKX52194.1 - 0.093 11.5 0.1 18 4.0 0.0 3.5 3 1 0 3 3 3 0 Nup133 N terminal like GAT PF03127.14 EKX52195.1 - 0.024 15.0 2.4 0.035 14.4 0.8 2.1 2 1 0 2 2 2 0 GAT domain DSPc PF00782.20 EKX52196.1 - 7.1e-08 32.3 0.0 1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DSPn PF14671.6 EKX52196.1 - 8.2e-07 29.5 0.2 0.004 17.6 0.0 3.4 2 1 1 3 3 3 2 Dual specificity protein phosphatase, N-terminal half Sec7 PF01369.20 EKX52197.1 - 7.5e-70 234.3 0.0 1.6e-69 233.3 0.0 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EKX52197.1 - 2.8e-33 115.1 2.0 2.8e-33 115.1 2.0 2.7 2 1 1 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 EKX52197.1 - 4.4e-07 29.7 0.0 2.7e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Cation_efflux PF01545.21 EKX52198.1 - 8.9e-11 41.9 1.8 8.9e-11 41.9 1.8 3.1 1 1 1 2 2 2 1 Cation efflux family DUF1963 PF09234.10 EKX52199.1 - 0.039 14.4 1.0 0.047 14.2 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1963) CCDC92 PF14916.6 EKX52199.1 - 0.042 13.6 0.1 0.042 13.6 0.1 3.5 2 2 2 4 4 4 0 Coiled-coil domain of unknown function MCC-bdg_PDZ PF10506.9 EKX52199.1 - 0.27 11.3 12.6 0.49 10.4 0.2 3.9 3 1 1 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Mis14 PF08641.12 EKX52199.1 - 0.31 11.4 9.8 0.14 12.5 5.2 2.0 1 1 1 2 2 2 0 Kinetochore protein Mis14 like CENP-H PF05837.12 EKX52199.1 - 0.41 11.1 18.0 0.17 12.3 5.4 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) NYD-SP28_assoc PF14775.6 EKX52199.1 - 0.54 10.4 0.2 0.54 10.4 0.2 3.1 3 1 0 3 3 3 0 Sperm tail C-terminal domain TSC22 PF01166.18 EKX52199.1 - 1.3 9.4 14.4 0.73 10.2 4.5 3.3 2 2 1 3 3 3 0 TSC-22/dip/bun family Fzo_mitofusin PF04799.13 EKX52199.1 - 1.5 8.4 8.3 0.8 9.2 4.7 1.9 1 1 1 2 2 2 0 fzo-like conserved region Jnk-SapK_ap_N PF09744.9 EKX52199.1 - 2 8.7 18.1 0.24 11.6 9.9 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 5_nucleotid PF05761.14 EKX52199.1 - 2.2 7.1 7.4 2.7 6.8 7.4 1.1 1 0 0 1 1 1 0 5' nucleotidase family Uso1_p115_C PF04871.13 EKX52199.1 - 2.7 8.4 16.9 22 5.4 16.9 2.3 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Herpes_BLRF2 PF05812.12 EKX52199.1 - 3.1 7.9 11.1 1 9.5 4.5 2.4 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein DUF1664 PF07889.12 EKX52199.1 - 6.1 6.9 8.0 2.9 7.9 1.5 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.15 EKX52199.1 - 7.2 6.5 18.9 2.3 8.0 3.2 3.6 2 2 1 3 3 3 0 Septum formation initiator RWP-RK PF02042.15 EKX52200.1 - 8.7e-13 48.0 0.5 1.2e-12 47.6 0.5 1.2 1 0 0 1 1 1 1 RWP-RK domain PIP5K PF01504.18 EKX52203.1 - 2.8e-70 236.7 0.4 1.2e-69 234.6 0.4 2.0 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase SpoIIIAH PF12685.7 EKX52204.1 - 0.026 14.4 0.3 0.028 14.3 0.3 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein PhoLip_ATPase_C PF16212.5 EKX52205.1 - 6.4e-70 235.7 24.8 6.4e-70 235.7 24.8 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EKX52205.1 - 2.8e-23 81.4 2.5 2.8e-23 81.4 2.5 2.2 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EKX52205.1 - 1.9e-13 50.3 0.0 1.5e-12 47.4 0.0 2.5 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EKX52205.1 - 1.7e-09 38.3 0.3 0.00088 19.6 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EKX52205.1 - 1e-06 28.4 2.5 1.1e-06 28.3 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EKX52205.1 - 0.025 14.3 0.2 0.13 12.0 0.0 2.2 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase E2F_TDP PF02319.20 EKX52206.1 - 9.1e-22 76.9 0.8 1.9e-21 75.9 0.8 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain DP PF08781.10 EKX52206.1 - 2e-17 63.4 2.4 2e-17 63.4 2.4 1.6 2 0 0 2 2 2 1 Transcription factor DP Defensin_propep PF00879.18 EKX52206.1 - 1.6 9.0 4.6 0.72 10.2 1.5 2.0 2 0 0 2 2 2 0 Defensin propeptide Arm PF00514.23 EKX52207.1 - 6.7e-09 35.5 2.6 8.2e-05 22.5 0.0 5.0 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EKX52207.1 - 0.00022 21.6 0.1 0.026 14.9 0.0 3.1 2 2 0 2 2 2 1 HEAT repeats Peptidase_C97 PF05903.14 EKX52207.1 - 0.057 13.2 0.5 0.17 11.7 0.2 1.9 3 0 0 3 3 3 0 PPPDE putative peptidase domain TAF1_subA PF14929.6 EKX52207.1 - 0.078 12.4 0.3 0.29 10.5 0.1 2.0 2 0 0 2 2 2 0 TAF RNA Polymerase I subunit A DUF2384 PF09722.10 EKX52207.1 - 0.079 13.0 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2384) HEAT_EZ PF13513.6 EKX52207.1 - 0.13 12.8 2.7 2.5 8.7 0.0 3.5 2 1 2 4 4 4 0 HEAT-like repeat Vanabin-2 PF11437.8 EKX52207.1 - 8.1 6.7 10.5 2.1 8.5 4.5 2.8 2 1 1 3 3 3 0 Vanadium-binding protein 2 E2F_TDP PF02319.20 EKX52208.1 - 7.7e-42 141.2 2.7 2e-20 72.6 0.1 2.8 3 0 0 3 3 3 2 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 EKX52208.1 - 0.00044 20.1 0.1 0.012 15.5 0.1 3.0 4 0 0 4 4 4 1 Sugar-specific transcriptional regulator TrmB Tht1 PF04163.12 EKX52208.1 - 0.058 12.1 0.5 0.16 10.7 0.1 1.8 1 1 1 2 2 2 0 Tht1-like nuclear fusion protein B-block_TFIIIC PF04182.12 EKX52208.1 - 0.068 13.3 0.0 3.4 7.9 0.0 2.3 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC MtN3_slv PF03083.16 EKX52209.1 - 1.9e-31 108.0 6.6 4.7e-20 71.4 2.3 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange DUF2407_C PF13373.6 EKX52209.1 - 0.48 10.6 1.7 1.7 8.9 0.2 2.2 2 0 0 2 2 2 0 DUF2407 C-terminal domain CSN8_PSD8_EIF3K PF10075.9 EKX52211.1 - 1.6e-22 80.0 0.1 1.9e-22 79.8 0.1 1.1 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family BLI1 PF17324.2 EKX52211.1 - 0.014 16.0 0.5 0.28 11.9 0.1 2.1 2 0 0 2 2 2 0 BLOC-1 interactor 1 DUF3418 PF11898.8 EKX52211.1 - 0.11 11.1 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) GCN5L1 PF06320.13 EKX52212.1 - 4.3e-34 117.1 6.9 4.7e-34 116.9 6.9 1.0 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) TF_AP-2 PF03299.14 EKX52212.1 - 0.0029 17.6 2.2 0.0057 16.6 1.9 1.5 2 0 0 2 2 2 1 Transcription factor AP-2 DUF1664 PF07889.12 EKX52212.1 - 0.0087 16.1 0.2 0.024 14.7 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) DUF1539 PF07560.11 EKX52212.1 - 0.013 15.5 0.1 0.021 14.9 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) DUF3802 PF12290.8 EKX52212.1 - 0.06 13.9 0.8 0.1 13.1 0.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3802) DUF4360 PF14273.6 EKX52212.1 - 0.081 12.8 0.1 0.11 12.3 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4360) Vps51 PF08700.11 EKX52212.1 - 0.18 11.9 3.2 0.59 10.2 3.2 1.9 1 1 0 1 1 1 0 Vps51/Vps67 DUF4618 PF15397.6 EKX52212.1 - 0.33 10.3 5.8 0.63 9.4 5.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Radical_SAM PF04055.21 EKX52214.1 - 1.5e-23 84.0 0.0 3.2e-23 82.9 0.0 1.5 2 0 0 2 2 2 1 Radical SAM superfamily HemN_C PF06969.16 EKX52214.1 - 1.3e-06 28.4 0.1 2.5e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 HemN C-terminal domain AA_kinase PF00696.28 EKX52215.1 - 7e-25 88.0 5.2 2e-23 83.3 5.2 2.1 1 1 0 1 1 1 1 Amino acid kinase family SCP2_2 PF13530.6 EKX52216.1 - 0.059 13.8 0.0 0.07 13.5 0.0 1.1 1 0 0 1 1 1 0 Sterol carrier protein domain Mito_carr PF00153.27 EKX52218.1 - 4.6e-24 84.2 8.6 3.5e-08 33.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Gp_dh_C PF02800.20 EKX52219.1 - 1.5e-54 183.8 0.0 5.7e-54 182.0 0.0 1.8 1 1 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EKX52219.1 - 3.3e-31 107.6 0.0 5.8e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Herpes_US12 PF05363.12 EKX52219.1 - 0.024 15.3 0.0 11 6.9 0.0 2.6 2 0 0 2 2 2 0 Herpesvirus US12 family 2-Hacid_dh_C PF02826.19 EKX52219.1 - 0.042 13.2 0.0 0.081 12.3 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_8 PF05148.15 EKX52220.1 - 2.9e-71 239.8 0.6 3.2e-71 239.7 0.6 1.0 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EKX52220.1 - 3.2e-07 30.9 0.5 1e-05 26.0 0.1 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX52220.1 - 0.00019 22.1 0.2 0.12 13.1 0.0 2.9 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX52220.1 - 0.00095 19.0 0.2 0.084 12.7 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.14 EKX52220.1 - 0.0016 18.1 0.0 0.028 14.0 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EKX52220.1 - 0.016 14.5 0.2 0.24 10.7 0.1 2.1 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family Xol-1_N PF09108.10 EKX52220.1 - 0.035 13.9 0.2 0.071 13.0 0.0 1.7 2 0 0 2 2 2 0 Switch protein XOL-1, N-terminal Bmt2 PF11968.8 EKX52220.1 - 0.05 13.4 0.2 2.7 7.8 0.2 2.1 1 1 0 1 1 1 0 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 PUB PF09409.10 EKX52220.1 - 0.12 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 PUB domain MetW PF07021.12 EKX52220.1 - 0.14 11.7 0.0 0.44 10.1 0.0 1.9 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW RRM_1 PF00076.22 EKX52221.1 - 1.3e-31 108.2 0.0 3.9e-17 61.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EKX52221.1 - 6.2e-05 23.0 0.0 0.0024 17.9 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 EKX52221.1 - 8e-05 22.6 0.0 0.47 10.5 0.0 2.2 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EKX52221.1 - 0.0028 17.5 0.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_7 PF16367.5 EKX52221.1 - 0.011 15.9 0.0 0.24 11.5 0.0 2.6 2 1 0 2 2 2 0 RNA recognition motif PHM7_cyt PF14703.6 EKX52221.1 - 0.084 13.1 0.0 14 5.8 0.0 2.7 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter RAP1 PF07218.11 EKX52221.1 - 0.67 8.2 2.8 0.78 7.9 2.8 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) EF-hand_7 PF13499.6 EKX52222.1 - 2.6e-11 43.8 1.1 3.1e-11 43.6 1.1 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX52222.1 - 6.8e-10 37.8 3.2 0.00027 20.2 0.3 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX52222.1 - 1.6e-07 30.7 3.7 0.00019 21.1 0.3 2.6 2 1 1 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 EKX52222.1 - 1.6e-06 27.3 4.5 0.002 17.5 0.4 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX52222.1 - 4.6e-05 23.2 3.3 0.00013 21.8 2.3 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 EKX52222.1 - 0.00073 19.4 0.1 0.00077 19.4 0.1 1.0 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SH3_3 PF08239.11 EKX52223.1 - 0.00053 20.2 0.1 0.00088 19.5 0.1 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain Cation_efflux PF01545.21 EKX52224.1 - 7.9e-44 149.8 15.3 9.8e-44 149.5 15.3 1.1 1 0 0 1 1 1 1 Cation efflux family zf-RING_2 PF13639.6 EKX52225.1 - 1.8e-11 44.2 7.3 1.8e-11 44.2 7.3 1.9 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 EKX52225.1 - 5.5e-10 38.8 7.8 5.5e-10 38.8 7.8 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 EKX52225.1 - 1.9e-08 34.1 10.3 2.1e-08 33.9 6.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX52225.1 - 9.1e-08 32.0 4.5 9.1e-08 32.0 4.5 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EKX52225.1 - 1.2e-07 31.6 5.7 2.9e-07 30.3 5.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EKX52225.1 - 1.9e-07 31.2 7.6 7.4e-07 29.4 7.6 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EKX52225.1 - 2.2e-06 27.4 2.9 4.8e-06 26.3 2.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EKX52225.1 - 4e-06 26.6 8.1 1.2e-05 25.0 8.1 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EKX52225.1 - 2.9e-05 24.0 2.3 5.9e-05 23.0 2.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 EKX52225.1 - 0.0004 20.5 2.9 0.0012 19.0 2.9 1.8 1 0 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.7 EKX52225.1 - 0.0012 18.9 5.3 0.0029 17.7 5.3 1.7 1 0 0 1 1 1 1 RING-variant domain Prok-RING_4 PF14447.6 EKX52225.1 - 0.0014 18.4 5.3 0.0033 17.2 5.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-3CxxC_2 PF17180.4 EKX52225.1 - 0.0054 17.4 0.1 0.011 16.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding domain Zn_ribbon_17 PF17120.5 EKX52225.1 - 0.0072 15.9 5.0 0.019 14.6 5.0 1.8 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type PHD PF00628.29 EKX52225.1 - 0.038 13.9 4.3 0.071 13.0 4.3 1.5 1 0 0 1 1 1 0 PHD-finger zf-Nse PF11789.8 EKX52225.1 - 0.07 13.0 2.3 0.13 12.1 2.3 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 EKX52225.1 - 0.15 11.9 5.2 0.13 12.1 3.3 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 EKX52225.1 - 8 6.7 9.9 2.5 8.3 5.5 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF3783 PF12646.7 EKX52226.1 - 0.0079 16.1 0.0 0.023 14.6 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3783) TbpB_B_D PF01298.18 EKX52226.1 - 0.11 12.8 0.1 0.2 12.0 0.1 1.3 1 0 0 1 1 1 0 C-lobe and N-lobe beta barrels of Tf-binding protein B AAA_33 PF13671.6 EKX52227.1 - 4e-08 33.5 7.1 6e-06 26.5 3.2 3.8 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 EKX52227.1 - 9.6e-08 31.7 0.1 0.019 14.8 0.0 2.6 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 EKX52227.1 - 9.9e-07 28.5 0.0 0.00063 19.2 0.0 2.4 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EKX52227.1 - 1.4e-06 28.7 0.0 0.0016 18.8 0.0 3.8 4 0 0 4 4 4 1 AAA domain UvrD-helicase PF00580.21 EKX52227.1 - 3.4e-06 26.8 2.1 5.1e-06 26.2 0.0 2.3 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 EKX52227.1 - 9.2e-06 26.1 0.0 0.21 12.0 0.0 3.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EKX52227.1 - 0.00033 20.9 0.0 0.25 11.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain PhoH PF02562.16 EKX52227.1 - 0.0011 18.5 0.0 0.77 9.2 0.0 3.2 3 0 0 3 3 3 1 PhoH-like protein ATPase PF06745.13 EKX52227.1 - 0.0011 18.3 0.0 0.43 9.9 0.0 2.4 2 0 0 2 2 2 2 KaiC ResIII PF04851.15 EKX52227.1 - 0.0026 17.8 0.0 0.013 15.5 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EKX52227.1 - 0.037 13.7 0.0 1.1 8.9 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 EKX52227.1 - 0.039 13.5 0.0 0.31 10.5 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 EKX52227.1 - 0.048 14.1 0.0 8.5 6.8 0.0 3.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EKX52227.1 - 0.052 13.1 0.0 2.4 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EKX52227.1 - 0.064 13.2 0.9 6.4 6.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EKX52227.1 - 0.071 12.8 0.0 16 5.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 EKX52227.1 - 0.11 11.8 0.0 4.7 6.5 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EKX52227.1 - 2.3 8.8 7.0 4.6 7.8 1.2 3.6 2 1 0 2 2 2 0 AAA domain C2 PF00168.30 EKX52228.1 - 4.6e-05 23.6 0.8 9.6e-05 22.6 0.8 1.5 1 1 0 1 1 1 1 C2 domain NaeI PF09126.10 EKX52228.1 - 0.035 13.3 0.1 0.044 13.0 0.1 1.1 1 0 0 1 1 1 0 Restriction endonuclease NaeI Peptidase_C48 PF02902.19 EKX52229.1 - 0.00023 21.1 0.1 0.00025 21.0 0.1 1.0 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain JAB PF01398.21 EKX52230.1 - 5.9e-08 32.7 0.6 1.8e-07 31.1 0.3 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EKX52230.1 - 5.3e-05 23.0 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain HSL_N PF06350.12 EKX52230.1 - 0.033 13.2 1.0 0.066 12.2 0.3 1.7 2 0 0 2 2 2 0 Hormone-sensitive lipase (HSL) N-terminus Sigma70_ner PF04546.13 EKX52230.1 - 0.086 12.7 0.0 0.086 12.7 0.0 2.8 3 0 0 3 3 3 0 Sigma-70, non-essential region HMw1_D2 PF18254.1 EKX52230.1 - 0.13 12.7 0.1 0.32 11.4 0.1 1.6 1 0 0 1 1 1 0 HMW1 domain 2 Ephrin_rec_like PF07699.13 EKX52232.1 - 0.081 12.7 0.7 0.081 12.7 0.7 4.0 3 1 1 4 4 4 0 Putative ephrin-receptor like Sec39 PF08314.11 EKX52233.1 - 8.4e-20 70.8 0.3 2e-07 29.9 0.0 3.4 2 1 1 3 3 3 3 Secretory pathway protein Sec39 Nbas_N PF15492.6 EKX52233.1 - 0.00088 18.7 0.0 0.0035 16.7 0.0 1.9 1 1 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal ANAPC4_WD40 PF12894.7 EKX52233.1 - 0.07 13.4 0.0 9.3 6.6 0.0 3.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EKX52234.1 - 1.4e-06 27.9 0.9 0.0057 16.0 0.0 2.2 2 0 0 2 2 2 2 WD40-like domain WD40 PF00400.32 EKX52234.1 - 1.7e-06 28.6 0.4 0.0013 19.6 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat Mcl1_mid PF12341.8 EKX52234.1 - 0.0059 16.0 0.4 1.2 8.4 0.1 2.4 1 1 1 2 2 2 2 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 EKX52234.1 - 0.021 15.1 0.2 5.3 7.4 0.1 3.5 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EKX52234.1 - 0.046 12.4 0.0 0.98 8.0 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EKX52234.1 - 0.077 11.7 0.2 0.27 9.9 0.0 1.8 2 0 0 2 2 2 0 Nup133 N terminal like AAA_6 PF12774.7 EKX52235.1 - 8.5e-152 504.8 0.1 6.4e-150 498.6 0.0 2.9 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EKX52235.1 - 3e-132 441.5 12.7 3e-132 441.5 12.7 3.6 4 1 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 EKX52235.1 - 3.9e-106 354.7 0.1 2e-105 352.4 0.1 2.4 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EKX52235.1 - 4.2e-90 300.7 2.1 7.5e-89 296.6 1.5 3.2 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 EKX52235.1 - 6e-82 273.5 1.4 3.8e-78 261.2 0.0 3.7 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_8 PF12780.7 EKX52235.1 - 2.4e-74 250.0 4.8 5.6e-43 147.1 0.0 4.2 4 1 1 5 5 5 2 P-loop containing dynein motor region D4 AAA_lid_11 PF18198.1 EKX52235.1 - 1.6e-55 187.4 2.3 2.5e-55 186.8 0.2 2.5 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 EKX52235.1 - 2.2e-50 171.6 9.4 4.3e-50 170.7 9.4 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EKX52235.1 - 1.3e-41 141.4 0.0 3.3e-40 136.9 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EKX52235.1 - 2.3e-29 102.1 0.7 1e-28 100.0 0.3 2.5 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EKX52235.1 - 3.4e-21 75.3 0.3 2.9e-19 69.1 0.0 3.6 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 EKX52235.1 - 8.1e-18 64.8 0.0 9.2e-06 25.7 0.0 5.3 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA PF00004.29 EKX52235.1 - 2e-08 34.7 0.2 0.18 12.2 0.0 5.9 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EKX52235.1 - 4.1e-07 30.3 0.4 0.14 12.5 0.0 4.7 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 EKX52235.1 - 5.9e-06 26.8 0.0 2.2 8.6 0.0 5.1 4 1 0 4 4 4 2 AAA ATPase domain AAA_18 PF13238.6 EKX52235.1 - 2.2e-05 25.0 0.0 0.005 17.4 0.0 4.6 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 EKX52235.1 - 0.00024 21.4 1.5 2.8 8.4 0.0 4.3 4 0 0 4 4 3 1 RNA helicase AAA_30 PF13604.6 EKX52235.1 - 0.0017 18.1 1.8 4.2 7.1 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_24 PF13479.6 EKX52235.1 - 0.013 15.2 1.1 4.2 7.0 0.0 3.4 4 0 0 4 4 3 0 AAA domain DUF853 PF05872.12 EKX52235.1 - 0.018 13.7 2.3 1.5 7.3 0.0 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) Mg_chelatase PF01078.21 EKX52235.1 - 0.028 13.8 0.6 2 7.8 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 EKX52235.1 - 0.032 14.5 1.6 10 6.4 0.0 4.1 4 0 0 4 4 3 0 AAA domain ResIII PF04851.15 EKX52235.1 - 0.064 13.3 0.0 0.064 13.3 0.0 4.2 5 0 0 5 5 4 0 Type III restriction enzyme, res subunit Baculo_PEP_C PF04513.12 EKX52235.1 - 0.069 13.2 0.0 26 4.8 0.0 4.4 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus T2SSE PF00437.20 EKX52235.1 - 0.67 9.0 2.8 3.7 6.5 0.0 3.4 4 0 0 4 4 4 0 Type II/IV secretion system protein SRP54 PF00448.22 EKX52235.1 - 4.8 6.8 7.1 28 4.3 0.1 3.7 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain HR1 PF02185.16 EKX52235.1 - 6.5 7.0 8.4 0.17 12.0 0.7 2.5 2 0 0 2 2 1 0 Hr1 repeat Kinesin PF00225.23 EKX52236.1 - 4.5e-109 364.4 3.7 7.3e-109 363.7 3.7 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX52236.1 - 8.1e-25 87.5 0.2 1.7e-24 86.5 0.2 1.5 1 0 0 1 1 1 1 Microtubule binding ABC_tran PF00005.27 EKX52237.1 - 7.7e-46 156.0 0.0 2e-25 89.9 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EKX52237.1 - 2.2e-20 73.7 0.2 4.9e-05 23.3 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 EKX52237.1 - 1.4e-13 50.7 0.4 1.5e-12 47.4 0.1 2.4 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EKX52237.1 - 1.5e-10 40.9 0.2 0.0078 15.7 0.0 3.8 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EKX52237.1 - 2.5e-07 30.3 0.0 0.015 15.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EKX52237.1 - 2.5e-07 30.8 0.0 0.0015 18.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 EKX52237.1 - 5.8e-07 30.2 3.2 0.011 16.2 0.0 3.2 4 0 0 4 4 4 2 AAA domain AAA_15 PF13175.6 EKX52237.1 - 3e-06 27.2 0.0 0.093 12.4 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 EKX52237.1 - 3e-06 27.3 0.0 0.091 12.8 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_30 PF13604.6 EKX52237.1 - 3.7e-05 23.5 0.0 0.009 15.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EKX52237.1 - 5.6e-05 23.7 0.2 0.22 12.1 0.1 3.2 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EKX52237.1 - 0.00015 22.1 0.0 0.078 13.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EKX52237.1 - 0.00023 21.6 0.0 0.82 10.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EKX52237.1 - 0.00033 20.9 1.2 0.5 10.6 0.1 3.5 2 2 1 3 3 3 1 AAA domain AAA_33 PF13671.6 EKX52237.1 - 0.00046 20.4 0.2 2.1 8.5 0.0 3.1 3 0 0 3 3 3 2 AAA domain NB-ARC PF00931.22 EKX52237.1 - 0.00054 19.2 0.0 0.12 11.5 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_27 PF13514.6 EKX52237.1 - 0.00069 19.3 0.0 0.23 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EKX52237.1 - 0.0011 19.0 0.0 1.1 9.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EKX52237.1 - 0.0014 19.0 0.0 1.8 9.0 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EKX52237.1 - 0.0015 18.3 0.0 0.37 10.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EKX52237.1 - 0.0023 17.9 0.0 1.5 8.8 0.0 2.5 2 0 0 2 2 2 1 NACHT domain NTPase_1 PF03266.15 EKX52237.1 - 0.0031 17.4 0.0 1.3 9.0 0.0 2.5 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.22 EKX52237.1 - 0.004 17.5 0.0 2 8.8 0.0 2.4 2 0 0 2 2 2 1 RNA helicase DUF87 PF01935.17 EKX52237.1 - 0.0056 16.8 0.1 1.1 9.3 0.0 3.0 3 0 0 3 3 2 1 Helicase HerA, central domain MeaB PF03308.16 EKX52237.1 - 0.0078 15.2 0.1 0.85 8.5 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF3584 PF12128.8 EKX52237.1 - 0.014 12.9 0.0 0.27 8.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) 5_3_exonuc_N PF02739.16 EKX52237.1 - 0.017 15.0 0.0 2.1 8.3 0.0 2.3 2 0 0 2 2 2 0 5'-3' exonuclease, N-terminal resolvase-like domain AAA_25 PF13481.6 EKX52237.1 - 0.02 14.5 0.0 7 6.2 0.1 2.8 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EKX52237.1 - 0.023 14.7 0.1 13 5.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 EKX52237.1 - 0.025 13.7 0.0 6.3 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SbcCD_C PF13558.6 EKX52237.1 - 0.033 14.4 0.2 2 8.7 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Roc PF08477.13 EKX52237.1 - 0.048 13.9 0.0 12 6.2 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EKX52237.1 - 0.078 13.0 0.0 2.2 8.3 0.0 2.7 2 1 0 2 2 2 0 Dynamin family ATPase_2 PF01637.18 EKX52237.1 - 0.081 12.8 0.0 3.3 7.5 0.0 2.6 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea ABC_ATPase PF09818.9 EKX52237.1 - 0.12 11.2 0.2 15 4.2 0.0 2.5 2 0 0 2 2 2 0 Predicted ATPase of the ABC class ATP_bind_1 PF03029.17 EKX52237.1 - 0.14 11.9 0.0 14 5.4 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SRP54 PF00448.22 EKX52237.1 - 0.18 11.4 0.0 18 4.9 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 EKX52237.1 - 0.43 9.8 1.7 6.3 6.0 0.1 2.6 3 0 0 3 3 3 0 Zeta toxin FeS_assembly_P PF01883.19 EKX52238.1 - 9e-10 38.6 0.0 2e-09 37.5 0.0 1.6 2 1 0 2 2 2 1 Iron-sulfur cluster assembly protein PWWP PF00855.17 EKX52239.1 - 0.00055 20.3 0.0 0.0022 18.4 0.0 2.1 1 0 0 1 1 1 1 PWWP domain PDZ_2 PF13180.6 EKX52239.1 - 0.047 14.0 0.0 0.19 12.1 0.0 2.0 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 EKX52239.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 PDZ domain zf-RING_UBOX PF13445.6 EKX52240.1 - 2e-10 40.5 9.0 4e-10 39.6 9.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EKX52240.1 - 5.9e-10 39.3 8.0 9.9e-10 38.6 8.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EKX52240.1 - 3.9e-09 36.2 7.1 6.9e-09 35.4 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX52240.1 - 5.1e-08 32.7 9.7 9.4e-08 31.8 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX52240.1 - 1.9e-07 30.9 7.9 3.8e-07 29.9 7.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EKX52240.1 - 2.2e-07 30.6 9.2 2.9e-06 27.1 3.6 2.3 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EKX52240.1 - 3.3e-07 30.1 9.7 6.5e-07 29.1 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EKX52240.1 - 1.1e-05 25.5 10.0 2.7e-05 24.2 10.0 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EKX52240.1 - 6.2e-05 22.7 5.1 0.00016 21.4 5.1 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EKX52240.1 - 0.00035 20.7 3.2 0.00069 19.7 3.2 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 EKX52240.1 - 0.0024 17.9 3.2 0.0044 17.0 3.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger SUIM_assoc PF16619.5 EKX52240.1 - 0.0038 17.3 0.2 0.0038 17.3 0.2 3.2 3 0 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 zf-rbx1 PF12678.7 EKX52240.1 - 0.0039 17.5 8.7 0.019 15.3 8.7 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EKX52240.1 - 0.0085 15.8 3.4 0.019 14.7 3.4 1.6 1 0 0 1 1 1 1 RING-like zinc finger U-box PF04564.15 EKX52240.1 - 0.011 15.8 0.0 0.039 14.1 0.0 2.0 1 0 0 1 1 1 0 U-box domain GAGA PF09237.11 EKX52240.1 - 0.048 13.5 4.4 0.51 10.2 0.0 2.9 2 0 0 2 2 2 0 GAGA factor zf-Di19 PF05605.12 EKX52240.1 - 0.16 12.3 4.4 7.5 6.9 1.3 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.7 EKX52240.1 - 0.19 11.8 5.9 0.56 10.3 5.9 1.8 1 1 0 1 1 1 0 Double zinc ribbon DUF812 PF05667.11 EKX52240.1 - 0.2 10.5 22.4 0.14 11.0 1.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF812) GPS2_interact PF15784.5 EKX52240.1 - 0.21 12.0 15.2 7.8 7.0 5.9 3.6 3 0 0 3 3 3 0 G-protein pathway suppressor 2-interacting domain zinc-ribbons_6 PF07191.12 EKX52240.1 - 0.27 11.3 4.5 0.71 9.9 4.5 1.7 1 0 0 1 1 1 0 zinc-ribbons DUF16 PF01519.16 EKX52240.1 - 0.27 11.7 12.1 0.074 13.5 3.9 2.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 FANCL_C PF11793.8 EKX52240.1 - 0.38 11.0 6.8 7.1 6.9 6.8 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.8 EKX52240.1 - 0.55 10.1 6.0 1.2 9.0 6.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF1664 PF07889.12 EKX52240.1 - 0.61 10.1 14.9 2 8.5 4.2 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 EKX52240.1 - 2.2 8.5 18.4 0.12 12.6 6.3 3.4 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain IBR PF01485.21 EKX52240.1 - 3.9 7.8 7.2 1 9.6 3.1 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Tup_N PF08581.10 EKX52240.1 - 5.1 7.5 20.0 1.4 9.3 5.0 3.4 2 1 1 3 3 3 0 Tup N-terminal RRM_1 PF00076.22 EKX52242.1 - 2.2e-14 53.0 0.0 5e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) hnRNP_Q_AcD PF18360.1 EKX52242.1 - 2.7e-07 30.5 0.1 5.4e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 Heterogeneous nuclear ribonucleoprotein Q acidic domain UCH PF00443.29 EKX52244.1 - 6.7e-27 94.6 0.0 7.9e-27 94.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EKX52244.1 - 3.3e-15 56.5 0.0 3.9e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 EKX52245.1 - 2.2e-18 66.7 1.1 2.4e-18 66.6 1.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EKX52245.1 - 7.4e-12 45.5 3.1 1.5e-11 44.5 3.1 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DAP_epimerase PF01678.19 EKX52247.1 - 0.13 12.5 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Diaminopimelate epimerase PdxA PF04166.12 EKX52248.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA VPS13 PF16908.5 EKX52249.1 - 1.5e-24 87.1 0.9 1.3e-23 84.0 0.1 3.0 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 EKX52249.1 - 5e-20 72.0 0.0 5.4e-19 68.6 0.0 2.4 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 GRAM PF02893.20 EKX52249.1 - 4.2e-17 62.1 0.0 1.7e-14 53.7 0.0 2.8 2 0 0 2 2 2 2 GRAM domain VPS13_mid_rpt PF16910.5 EKX52249.1 - 3.9e-14 52.7 2.9 5.6e-05 22.7 0.1 4.8 4 0 0 4 4 4 3 Repeating coiled region of VPS13 FHA PF00498.26 EKX52249.1 - 2.2e-13 50.4 0.1 9.7e-13 48.3 0.1 2.3 1 0 0 1 1 1 1 FHA domain Chorein_N PF12624.7 EKX52249.1 - 1.9e-09 37.6 3.4 6.6e-09 35.9 3.4 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 Yop-YscD_cpl PF16697.5 EKX52249.1 - 8.8e-07 29.2 0.0 3.4e-06 27.3 0.0 2.0 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain mRNA_decap_C PF16741.5 EKX52249.1 - 0.64 9.4 2.6 0.43 9.9 0.1 2.0 2 0 0 2 2 2 0 mRNA-decapping enzyme C-terminus ZU5 PF00791.20 EKX52251.1 - 2e-05 24.8 0.0 4.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 ZU5 domain PDZ PF00595.24 EKX52252.1 - 0.0002 21.7 0.0 0.00032 21.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX52252.1 - 0.0013 18.5 0.1 0.0023 17.7 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX52252.1 - 0.013 15.8 0.1 0.018 15.3 0.1 1.3 1 0 0 1 1 1 0 PDZ domain DUF4112 PF13430.6 EKX52254.1 - 0.031 14.5 0.4 0.066 13.5 0.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4112) ImmE5 PF11480.8 EKX52255.1 - 0.075 13.5 0.0 0.56 10.7 0.0 2.5 2 0 0 2 2 2 0 Colicin-E5 Imm protein Androgen_recep PF02166.16 EKX52255.1 - 0.66 8.8 3.8 1.1 8.1 3.8 1.3 1 0 0 1 1 1 0 Androgen receptor PRIMA1 PF16101.5 EKX52255.1 - 1.7 8.7 6.0 6.2 6.9 6.0 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 LNS2 PF08235.13 EKX52256.1 - 6.5e-53 179.5 0.0 9.4e-53 179.0 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EKX52256.1 - 1.9e-05 24.6 0.1 4.1e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region Hydrolase_6 PF13344.6 EKX52256.1 - 0.0018 18.4 0.0 0.0035 17.4 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EKX52256.1 - 0.074 12.8 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2183 PF09949.9 EKX52256.1 - 0.12 12.7 0.0 0.51 10.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) IMCp PF12314.8 EKX52257.1 - 0.0012 19.0 53.7 0.0026 18.0 24.9 2.8 2 0 0 2 2 2 2 Inner membrane complex protein FYVE PF01363.21 EKX52258.1 - 4.3e-26 90.8 28.0 2.7e-16 59.5 10.6 2.8 2 0 0 2 2 2 2 FYVE zinc finger C2 PF00168.30 EKX52258.1 - 3.1e-06 27.4 0.0 6.9e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain IBR PF01485.21 EKX52258.1 - 2 8.7 30.1 0.12 12.6 4.3 3.6 4 0 0 4 4 4 0 IBR domain, a half RING-finger domain zf-AN1 PF01428.16 EKX52258.1 - 5.9 7.1 25.8 2.1 8.6 9.3 2.9 2 0 0 2 2 2 0 AN1-like Zinc finger Alanine_zipper PF11839.8 EKX52259.1 - 0.0072 16.7 26.1 0.021 15.2 5.3 2.3 2 0 0 2 2 2 2 Alanine-zipper, major outer membrane lipoprotein GARP PF16731.5 EKX52259.1 - 0.047 13.4 14.7 0.1 12.3 2.1 2.2 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma AAA_13 PF13166.6 EKX52259.1 - 0.39 9.3 6.2 0.052 12.2 1.8 1.6 1 1 1 2 2 2 0 AAA domain HBM PF16591.5 EKX52260.1 - 0.00094 18.7 9.1 0.0013 18.2 9.1 1.3 1 0 0 1 1 1 1 Helical bimodular sensor domain Tsc35 PF15079.6 EKX52260.1 - 0.0076 15.9 2.5 0.011 15.3 2.5 1.3 1 0 0 1 1 1 1 Testis-specific protein 35 PEP-utilisers_N PF05524.13 EKX52260.1 - 0.073 13.3 6.9 0.14 12.3 6.9 1.5 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Peptidase_M76 PF09768.9 EKX52260.1 - 0.15 11.8 2.9 0.65 9.8 2.9 2.0 1 1 0 1 1 1 0 Peptidase M76 family DUF3053 PF11254.8 EKX52260.1 - 0.36 10.4 12.6 0.34 10.5 9.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3053) Sec8_exocyst PF04048.14 EKX52260.1 - 0.55 10.1 8.4 0.097 12.6 3.1 2.1 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain GAS PF13851.6 EKX52260.1 - 0.59 9.5 16.4 2.9 7.2 9.7 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding FIVAR PF07554.13 EKX52260.1 - 1.8 9.4 14.2 8 7.3 9.1 2.5 1 1 1 2 2 2 0 FIVAR domain BRE1 PF08647.11 EKX52260.1 - 2 8.5 18.3 0.75 9.9 10.1 2.5 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF390 PF04094.14 EKX52260.1 - 2.5 6.3 11.1 3.1 6.0 11.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF390) DUF4407 PF14362.6 EKX52260.1 - 3.8 6.8 16.4 2.3 7.5 14.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 EKX52260.1 - 4.1 7.8 13.0 6.9 7.1 13.0 1.4 1 1 0 1 1 1 0 Fez1 Seryl_tRNA_N PF02403.22 EKX52260.1 - 7.1 6.9 12.9 1.1 9.5 7.6 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Alanine_zipper PF11839.8 EKX52260.1 - 8.8 6.8 23.2 3.8 8.0 8.0 2.6 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein T3SSipB PF16535.5 EKX52260.1 - 9.4 6.7 22.1 19 5.7 22.0 1.7 1 1 0 1 1 1 0 Type III cell invasion protein SipB 2OG-FeII_Oxy_3 PF13640.6 EKX52261.1 - 8.7e-07 29.8 0.0 1.5e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EKX52261.1 - 0.014 15.9 0.0 0.031 14.8 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily ABC1 PF03109.16 EKX52262.1 - 8.5e-30 103.4 0.1 2.1e-29 102.1 0.1 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EKX52262.1 - 0.001 19.1 0.0 0.0038 17.2 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 EKX52262.1 - 0.078 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Ank_2 PF12796.7 EKX52263.1 - 1.6e-21 76.7 0.6 1.5e-09 38.3 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX52263.1 - 1e-19 70.6 1.0 6.1e-09 36.3 0.0 4.9 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX52263.1 - 1.4e-18 66.7 1.5 6.8e-07 29.5 0.1 5.4 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX52263.1 - 3.8e-13 49.2 4.2 0.0068 16.8 0.2 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EKX52263.1 - 2.8e-12 45.7 1.9 0.018 15.5 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat DUF3253 PF11625.8 EKX52263.1 - 0.095 12.9 4.4 1.7 8.9 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3253) Prok-TraM PF09228.10 EKX52263.1 - 0.23 11.8 3.1 0.21 12.0 0.4 2.3 2 0 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM WD40 PF00400.32 EKX52264.1 - 1.7e-56 186.9 14.4 1.2e-07 32.3 0.1 8.6 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX52264.1 - 2.2e-21 75.9 5.0 4e-05 23.8 0.0 7.1 1 1 7 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX52264.1 - 2e-07 30.3 0.8 0.069 12.1 0.0 4.8 2 2 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EKX52264.1 - 1.1e-06 27.7 9.6 0.066 11.8 0.0 5.7 5 1 1 6 6 6 3 Nucleoporin Nup120/160 eIF2A PF08662.11 EKX52264.1 - 8.4e-06 25.8 0.1 0.0054 16.6 0.0 3.3 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Fim-adh_lectin PF09222.10 EKX52264.1 - 0.031 13.8 1.5 0.085 12.4 0.8 2.1 2 1 0 2 2 2 0 Fimbrial adhesin F17-AG, lectin domain PD40 PF07676.12 EKX52264.1 - 0.082 12.9 0.0 0.48 10.4 0.0 2.4 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Big_7 PF17957.1 EKX52264.1 - 0.094 13.5 1.8 0.83 10.5 0.6 3.0 2 1 0 2 2 2 0 Bacterial Ig domain LRR_8 PF13855.6 EKX52266.1 - 4.1e-08 32.9 1.6 7.7e-08 32.0 1.6 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.33 EKX52266.1 - 0.052 14.1 1.3 4.7 8.1 0.0 3.1 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_4 PF12799.7 EKX52266.1 - 0.13 12.7 1.4 0.5 10.9 0.3 2.1 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) PRIMA1 PF16101.5 EKX52266.1 - 0.19 11.8 4.8 0.094 12.8 2.7 1.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 LRR_5 PF13306.6 EKX52266.1 - 0.19 11.7 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) Aminotran_1_2 PF00155.21 EKX52267.1 - 1.3e-53 182.5 0.0 1.7e-53 182.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II MORN PF02493.20 EKX52269.1 - 2.8e-27 93.0 40.1 3.8e-06 26.5 1.7 5.2 5 0 0 5 5 5 5 MORN repeat Tudor_2 PF18104.1 EKX52269.1 - 0.00049 19.7 10.2 1.2 8.8 1.2 4.5 4 1 0 4 4 4 3 Jumonji domain-containing protein 2A Tudor domain Exostosin PF03016.15 EKX52270.1 - 7.2e-07 28.7 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Exostosin family MIP PF00230.20 EKX52271.1 - 3.3e-41 141.5 13.5 4.3e-41 141.1 13.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein ThrE PF06738.12 EKX52271.1 - 1.8 7.9 16.1 0.31 10.4 0.2 3.2 2 1 1 3 3 3 0 Putative threonine/serine exporter zf-RING_2 PF13639.6 EKX52272.1 - 5e-12 45.9 6.2 1.4e-11 44.6 6.2 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX52272.1 - 2.3e-09 36.9 7.0 1.1e-08 34.8 7.0 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX52272.1 - 2.2e-08 33.9 3.2 5.8e-08 32.6 3.2 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EKX52272.1 - 3e-08 33.8 7.4 1.3e-07 31.8 7.4 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EKX52272.1 - 5.2e-08 32.5 2.3 5.2e-08 32.5 2.3 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EKX52272.1 - 1.8e-06 27.9 0.8 1.8e-06 27.9 0.8 2.2 2 1 0 2 2 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EKX52272.1 - 7.1e-06 26.0 1.6 1.9e-05 24.6 1.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EKX52272.1 - 7.3e-06 25.8 3.9 1.6e-05 24.6 3.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EKX52272.1 - 9.5e-06 25.1 4.6 2.4e-05 23.9 4.6 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 EKX52272.1 - 2.7e-05 23.9 4.8 2.7e-05 23.9 4.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX52272.1 - 4.9e-05 23.1 4.1 4.9e-05 23.1 4.1 1.9 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 RINGv PF12906.7 EKX52272.1 - 0.0044 17.1 3.0 0.011 15.9 3.0 1.7 1 1 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 EKX52272.1 - 0.0084 16.3 4.0 0.037 14.2 4.0 2.1 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_4 PF14570.6 EKX52272.1 - 0.18 11.6 3.3 0.38 10.6 3.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zf_RING PF16744.5 EKX52272.1 - 0.35 11.0 3.0 0.87 9.7 3.0 1.7 1 1 0 1 1 1 0 KIAA1045 RING finger zf-C3HC4_4 PF15227.6 EKX52272.1 - 1.3 9.2 5.1 0.6 10.3 0.8 2.7 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING DUF2306 PF10067.9 EKX52272.1 - 1.9 8.7 13.6 0.6 10.3 4.3 2.7 1 1 2 3 3 3 0 Predicted membrane protein (DUF2306) zf-RING-like PF08746.11 EKX52272.1 - 7.9 6.9 7.1 0.72 10.2 2.0 1.9 2 0 0 2 2 1 0 RING-like domain ThiF PF00899.21 EKX52273.1 - 2.4e-72 243.2 0.1 3e-72 242.9 0.1 1.0 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 EKX52273.1 - 2.2e-08 34.3 0.2 8.7e-06 25.8 0.1 2.3 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 EKX52273.1 - 7.6e-07 29.5 0.8 3.8e-06 27.3 0.1 2.4 3 0 0 3 3 3 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 EKX52273.1 - 0.00012 22.1 0.6 0.00032 20.8 0.1 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Spermine_synth PF01564.17 EKX52273.1 - 0.0027 17.2 0.1 0.0065 15.9 0.1 1.6 1 0 0 1 1 1 1 Spermine/spermidine synthase domain UAE_UbL PF14732.6 EKX52273.1 - 0.0089 16.6 0.1 0.018 15.6 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Pyr_redox PF00070.27 EKX52273.1 - 0.014 16.0 0.4 0.12 12.9 0.2 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase KH_1 PF00013.29 EKX52276.1 - 3.7e-07 29.9 0.0 3.9e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 KH domain dCache_1 PF02743.18 EKX52277.1 - 8.9e-10 38.8 0.1 0.0011 18.8 0.0 3.7 3 1 0 3 3 3 3 Cache domain Keratin_2_head PF16208.5 EKX52277.1 - 0.007 16.5 10.5 0.016 15.4 10.5 1.6 1 0 0 1 1 1 1 Keratin type II head Allexi_40kDa PF05549.11 EKX52277.1 - 0.36 10.3 4.2 0.12 11.8 1.1 1.7 2 0 0 2 2 2 0 Allexivirus 40kDa protein Spore_III_AB PF09548.10 EKX52277.1 - 0.54 10.3 4.9 1.8 8.6 4.5 2.2 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) HAUS5 PF14817.6 EKX52278.1 - 4.3e-08 32.4 5.5 4.3e-08 32.4 5.5 3.5 2 2 1 3 3 3 1 HAUS augmin-like complex subunit 5 Pyr_redox_2 PF07992.14 EKX52279.1 - 2.4e-49 168.2 0.2 2.9e-49 167.9 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EKX52279.1 - 1.9e-21 76.4 0.1 4.9e-21 75.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EKX52279.1 - 2.3e-16 60.1 0.0 2.5e-13 50.4 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EKX52279.1 - 2.8e-06 26.7 0.8 5.2e-06 25.8 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EKX52279.1 - 0.00011 21.5 0.4 0.00017 20.8 0.4 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EKX52279.1 - 0.00011 21.5 0.2 0.078 12.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EKX52279.1 - 0.00022 20.9 1.4 0.0055 16.3 1.4 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EKX52279.1 - 0.00061 18.6 0.9 0.00099 17.9 0.3 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 EKX52279.1 - 0.0027 17.1 1.6 0.004 16.6 0.8 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EKX52279.1 - 0.0034 16.6 0.1 0.012 14.9 0.1 1.8 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 EKX52279.1 - 0.036 13.4 0.0 0.21 10.9 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.6 EKX52279.1 - 0.096 13.2 0.1 12 6.5 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_8 PF13450.6 EKX52279.1 - 0.12 12.7 0.3 0.12 12.7 0.3 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EKX52279.1 - 0.19 10.8 0.0 0.71 8.9 0.0 1.9 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DED PF01335.21 EKX52280.1 - 0.011 16.0 0.1 0.016 15.5 0.1 1.2 1 0 0 1 1 1 0 Death effector domain SET PF00856.28 EKX52281.1 - 1.4e-05 25.6 0.0 0.00016 22.1 0.0 2.3 2 1 0 2 2 2 1 SET domain Paf1 PF03985.13 EKX52282.1 - 4.6e-63 213.7 11.7 5.9e-63 213.3 11.7 1.0 1 0 0 1 1 1 1 Paf1 DUF4692 PF15763.5 EKX52282.1 - 2.6 8.5 6.0 1.8 9.0 3.7 1.9 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) SNF5 PF04855.12 EKX52283.1 - 2.8e-33 115.7 3.8 1e-32 113.8 0.8 2.4 2 1 0 2 2 2 1 SNF5 / SMARCB1 / INI1 Guanylin PF02058.15 EKX52283.1 - 0.0018 18.7 0.0 1.7 9.2 0.0 2.5 2 0 0 2 2 2 2 Guanylin precursor DUF4459 PF14673.6 EKX52283.1 - 0.049 13.6 0.1 0.087 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4459) CVNH PF08881.10 EKX52284.1 - 0.14 12.8 0.0 0.25 12.1 0.0 1.4 1 0 0 1 1 1 0 CVNH domain KH_1 PF00013.29 EKX52285.1 - 1.9e-36 123.7 10.3 1.5e-12 47.2 0.6 3.3 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 EKX52285.1 - 5.3e-07 29.5 0.2 0.06 13.4 0.0 3.3 3 0 0 3 3 3 3 KH-like RNA-binding domain KH_2 PF07650.17 EKX52285.1 - 4.5e-06 26.4 12.2 0.0015 18.3 0.3 3.6 2 1 1 3 3 3 2 KH domain Ribosomal_L23eN PF03939.13 EKX52285.1 - 0.003 17.7 0.3 0.009 16.2 0.3 1.8 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Prefoldin PF02996.17 EKX52286.1 - 3.9e-27 94.5 1.8 4.5e-27 94.4 1.0 1.5 1 1 1 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.20 EKX52286.1 - 0.003 17.5 1.0 0.03 14.3 0.0 2.2 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_3 PF13758.6 EKX52286.1 - 0.031 14.3 0.1 0.05 13.7 0.1 1.5 1 1 0 1 1 1 0 Prefoldin subunit APG6_N PF17675.1 EKX52286.1 - 0.041 14.4 2.5 0.74 10.4 0.3 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region Prot_ATP_ID_OB PF16450.5 EKX52286.1 - 0.08 12.9 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain Tropomyosin_1 PF12718.7 EKX52286.1 - 0.17 12.0 2.7 0.97 9.6 0.3 2.2 2 0 0 2 2 2 0 Tropomyosin like Sec2p PF06428.11 EKX52286.1 - 0.19 11.7 2.7 1.9 8.5 0.5 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p TPR_MLP1_2 PF07926.12 EKX52286.1 - 0.33 11.0 4.7 3.7 7.6 0.3 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein ZapB PF06005.12 EKX52286.1 - 0.46 11.0 4.4 2.5 8.6 0.4 2.3 2 1 0 2 2 2 0 Cell division protein ZapB DEAD PF00270.29 EKX52287.1 - 7.5e-44 149.6 0.0 1.3e-42 145.5 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX52287.1 - 3.2e-29 101.5 0.0 7.8e-29 100.3 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX52287.1 - 6.2e-05 23.1 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EKX52287.1 - 0.0085 15.8 0.0 0.54 10.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.6 EKX52287.1 - 0.013 14.8 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 EKX52287.1 - 0.064 13.5 0.0 7.3 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.16 EKX52288.1 - 3e-42 144.8 34.2 1.4e-32 113.0 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EKX52288.1 - 1.3e-37 129.7 18.0 2.7e-37 128.7 17.8 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3734 PF12536.8 EKX52288.1 - 0.26 11.7 0.0 0.43 10.9 0.0 1.2 1 0 0 1 1 1 0 Patatin phospholipase DUF389 PF04087.14 EKX52288.1 - 1.5 8.9 14.3 0.33 11.0 1.2 3.2 2 2 1 3 3 3 0 Domain of unknown function (DUF389) DUF2178 PF09946.9 EKX52288.1 - 2.8 8.2 8.1 0.14 12.3 0.5 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2178) CRAL_TRIO PF00650.20 EKX52289.1 - 9.1e-16 58.0 0.8 3.2e-15 56.2 0.8 1.8 1 1 0 1 1 1 1 CRAL/TRIO domain COG2 PF06148.11 EKX52290.1 - 0.034 14.2 0.5 0.058 13.5 0.5 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 EKX52290.1 - 0.036 12.9 3.6 0.05 12.5 3.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2385 PF09539.10 EKX52290.1 - 0.053 14.0 1.2 0.11 13.0 0.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2385) Fez1 PF06818.15 EKX52290.1 - 0.062 13.7 6.1 0.083 13.3 5.9 1.4 1 1 0 1 1 1 0 Fez1 KIX_2 PF16987.5 EKX52292.1 - 0.026 14.5 1.0 0.04 13.9 1.0 1.4 1 1 0 1 1 1 0 KIX domain Asp PF00026.23 EKX52294.1 - 2.5e-32 112.6 0.1 8.6e-22 77.9 0.0 2.8 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EKX52294.1 - 5.3e-09 36.6 0.1 0.00057 20.2 0.0 2.4 2 0 0 2 2 2 2 Xylanase inhibitor N-terminal Hist_deacetyl PF00850.19 EKX52295.1 - 5e-81 272.5 0.1 1e-80 271.5 0.1 1.4 1 1 0 1 1 1 1 Histone deacetylase domain 7TMR-HDED PF07697.11 EKX52296.1 - 0.073 13.2 0.4 0.16 12.1 0.4 1.5 1 0 0 1 1 1 0 7TM-HD extracellular Phage_Integr_2 PF13009.6 EKX52296.1 - 0.32 10.1 1.9 0.5 9.4 1.9 1.3 1 0 0 1 1 1 0 Putative phage integrase DUF1002 PF06207.11 EKX52296.1 - 0.37 10.3 5.6 0.62 9.6 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) DUF1295 PF06966.12 EKX52297.1 - 6.1e-62 209.2 0.1 7.1e-62 209.0 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 EKX52297.1 - 1.8e-06 28.0 0.2 3.8e-06 26.9 0.2 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 EKX52297.1 - 1.8e-05 25.1 0.3 4.9e-05 23.7 0.1 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EKX52297.1 - 0.01 16.2 0.1 0.01 16.2 0.1 2.0 2 0 0 2 2 2 0 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EKX52297.1 - 0.035 12.9 0.9 0.1 11.3 0.9 1.8 1 1 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family Integrin_beta PF00362.18 EKX52298.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Integrin beta chain VWA domain Ank_2 PF12796.7 EKX52299.1 - 1e-23 83.7 0.1 1.5e-08 35.1 0.0 3.4 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX52299.1 - 5.1e-16 58.8 1.1 0.00035 21.1 0.1 4.5 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX52299.1 - 3.7e-15 55.8 0.3 1.7e-07 31.4 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX52299.1 - 2.3e-10 40.4 0.7 0.00013 22.2 0.2 5.4 5 0 0 5 5 5 1 Ankyrin repeat Ank_3 PF13606.6 EKX52299.1 - 3.7e-10 39.1 0.1 0.0048 17.3 0.1 5.1 5 0 0 5 5 5 2 Ankyrin repeat UPF0020 PF01170.18 EKX52299.1 - 4.8e-06 26.4 0.1 0.0037 17.0 0.0 2.3 1 1 1 2 2 2 2 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 EKX52299.1 - 0.00051 19.8 0.0 0.0088 15.8 0.0 2.3 2 0 0 2 2 2 1 DNA methylase Cons_hypoth95 PF03602.15 EKX52299.1 - 0.078 12.6 0.1 8.6 6.0 0.0 2.2 1 1 0 2 2 2 0 Conserved hypothetical protein 95 Tudor-knot PF11717.8 EKX52300.1 - 4.3e-05 23.3 1.2 0.00016 21.5 0.2 2.6 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain DOCK-C2 PF14429.6 EKX52301.1 - 5.8e-06 26.2 0.0 0.025 14.4 0.0 4.1 5 0 0 5 5 5 2 C2 domain in Dock180 and Zizimin proteins PI3K_C2 PF00792.24 EKX52301.1 - 0.0007 19.5 0.0 0.67 9.9 0.0 3.9 3 0 0 3 3 3 2 Phosphoinositide 3-kinase C2 VMA21 PF09446.10 EKX52302.1 - 8.9e-10 38.5 8.3 1.1e-09 38.2 8.3 1.1 1 0 0 1 1 1 1 VMA21-like domain Wzy_C PF04932.15 EKX52302.1 - 0.078 12.6 0.0 0.089 12.4 0.0 1.1 1 0 0 1 1 1 0 O-Antigen ligase PRA1 PF03208.19 EKX52302.1 - 0.12 11.9 2.8 0.16 11.6 2.8 1.1 1 0 0 1 1 1 0 PRA1 family protein FF PF01846.19 EKX52303.1 - 3.9e-21 75.0 17.5 3.9e-07 30.1 0.0 6.3 4 1 1 5 5 5 4 FF domain WW PF00397.26 EKX52303.1 - 1.4e-09 37.9 4.1 3.6e-06 26.9 0.2 2.9 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 EKX52303.1 - 0.00016 22.3 3.1 0.009 16.7 0.0 3.1 2 1 0 2 2 2 1 p190-A and -B Rho GAPs FF domain Glyco_hyd_101C PF17451.2 EKX52303.1 - 0.0088 16.3 0.2 0.48 10.7 0.0 2.9 2 0 0 2 2 2 1 Glycosyl hydrolase 101 beta sandwich domain GRP PF07172.11 EKX52304.1 - 0.064 13.9 0.1 0.92 10.2 0.1 2.1 2 0 0 2 2 2 0 Glycine rich protein family Amidohydro_1 PF01979.20 EKX52304.1 - 0.11 11.8 0.5 0.13 11.6 0.5 1.1 1 0 0 1 1 1 0 Amidohydrolase family FbpA PF05833.11 EKX52305.1 - 4.7e-40 137.7 2.7 7.7e-40 137.0 2.7 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 EKX52305.1 - 2.3e-31 108.7 0.0 6.7e-31 107.2 0.0 1.9 1 0 0 1 1 1 1 NFACT protein RNA binding domain DUF148 PF02520.17 EKX52305.1 - 1.8 8.7 9.8 0.51 10.5 4.4 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF148 U-box PF04564.15 EKX52306.1 - 3.9e-19 68.6 0.2 4.5e-19 68.4 0.2 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX52306.1 - 4.6e-07 29.5 0.1 6.1e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EKX52306.1 - 0.001 19.0 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-NOSIP PF15906.5 EKX52306.1 - 0.0028 17.7 0.0 0.0035 17.5 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_2 PF13923.6 EKX52306.1 - 0.033 14.0 0.0 0.048 13.5 0.0 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX52306.1 - 0.071 13.4 0.1 0.11 12.8 0.1 1.4 1 1 0 1 1 1 0 RING-H2 zinc finger domain Pkinase_Tyr PF07714.17 EKX52307.1 - 5e-21 75.1 0.3 5.7e-21 75.0 0.3 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX52307.1 - 8e-13 48.4 0.3 9e-13 48.2 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain RL PF17797.1 EKX52307.1 - 0.01 15.8 0.2 0.017 15.0 0.2 1.4 1 0 0 1 1 1 0 RL domain Pkinase_Tyr PF07714.17 EKX52308.1 - 2.4e-24 86.0 0.3 2.6e-24 85.9 0.3 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX52308.1 - 1.7e-08 34.1 0.0 1.9e-08 34.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain UQ_con PF00179.26 EKX52309.1 - 7.1e-22 77.6 0.0 8.9e-22 77.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EKX52309.1 - 0.015 15.6 0.0 0.017 15.4 0.0 1.3 1 0 0 1 1 1 0 RWD domain Prok-E2_E PF14462.6 EKX52309.1 - 0.12 12.2 0.2 1.2 9.0 0.2 2.1 1 1 0 1 1 1 0 Prokaryotic E2 family E BRE PF06113.12 EKX52309.1 - 0.19 10.5 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) Pro_isomerase PF00160.21 EKX52312.1 - 1.7e-47 161.6 0.2 2e-47 161.4 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HemX PF04375.14 EKX52313.1 - 0.07 12.4 0.1 0.09 12.1 0.1 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF412 PF04217.13 EKX52313.1 - 0.16 11.9 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF412 DUF599 PF04654.12 EKX52314.1 - 1.1e-31 109.9 9.7 2.1e-31 109.0 9.7 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF599 NYD-SP28_assoc PF14775.6 EKX52314.1 - 0.037 14.1 0.5 0.037 14.1 0.5 5.2 3 0 0 3 3 3 0 Sperm tail C-terminal domain CTNNBL PF08216.11 EKX52315.1 - 8e-31 106.3 0.8 2.4e-30 104.8 0.8 1.9 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear Atx10homo_assoc PF09759.9 EKX52315.1 - 0.018 15.1 0.0 0.052 13.6 0.0 1.8 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 EKX52315.1 - 0.063 13.7 0.1 0.73 10.3 0.1 2.6 1 1 1 2 2 2 0 HEAT repeats Arm PF00514.23 EKX52315.1 - 0.11 12.5 0.0 2 8.6 0.0 2.6 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Dynactin_p22 PF07426.11 EKX52315.1 - 0.12 12.2 3.0 0.5 10.2 2.7 2.1 1 1 1 2 2 2 0 Dynactin subunit p22 Ly-6_related PF06579.12 EKX52316.1 - 0.16 12.2 9.3 5.3 7.3 0.7 2.7 1 1 2 3 3 3 0 Caenorhabditis elegans ly-6-related protein PDZ_6 PF17820.1 EKX52317.1 - 5.1e-13 48.6 0.3 1e-12 47.7 0.3 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX52317.1 - 5e-10 39.6 0.0 8.7e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX52317.1 - 5.4e-05 23.4 0.1 9.4e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX52317.1 - 0.012 15.5 0.1 0.024 14.6 0.1 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain SNARE PF05739.19 EKX52318.1 - 4.3e-15 55.4 0.2 9.6e-15 54.3 0.2 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 EKX52318.1 - 0.001 19.4 3.0 0.001 19.4 3.0 2.9 3 1 0 3 3 3 1 Syntaxin-like protein T2SSF PF00482.23 EKX52318.1 - 0.0044 17.0 2.0 0.0071 16.3 0.3 2.2 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein F Prominin PF05478.11 EKX52318.1 - 0.012 13.6 3.7 0.021 12.8 3.7 1.4 1 1 0 1 1 1 0 Prominin CEP44 PF15007.6 EKX52318.1 - 0.055 13.6 0.9 0.11 12.6 0.9 1.5 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 Med9 PF07544.13 EKX52318.1 - 0.14 12.3 6.3 0.093 12.8 2.6 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Syntaxin PF00804.25 EKX52318.1 - 0.16 11.7 15.4 10 5.7 15.4 2.3 1 1 0 1 1 1 0 Syntaxin DUF16 PF01519.16 EKX52318.1 - 0.19 12.2 7.7 0.14 12.6 5.2 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 Cytochrom_C_2 PF01322.20 EKX52318.1 - 0.22 12.4 4.1 1.9 9.4 0.0 2.9 1 1 2 3 3 3 0 Cytochrome C' I_LWEQ PF01608.17 EKX52318.1 - 0.28 11.4 7.2 0.87 9.8 4.7 2.2 2 0 0 2 2 2 0 I/LWEQ domain CwfJ_C_2 PF04676.14 EKX52318.1 - 2 9.3 4.7 0.71 10.8 1.1 1.9 2 0 0 2 2 2 0 Protein similar to CwfJ C-terminus 2 DUF2203 PF09969.9 EKX52318.1 - 7.6 7.3 7.8 13 6.5 3.0 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Vps53_N PF04100.12 EKX52319.1 - 2.6e-97 326.2 2.5 3.7e-97 325.7 2.5 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 EKX52319.1 - 3.8e-06 26.4 7.9 5.7e-06 25.8 4.9 2.1 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 EKX52319.1 - 0.21 11.7 4.6 0.63 10.1 3.1 2.7 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 EKX52319.1 - 0.29 11.3 5.6 0.48 10.6 2.6 2.7 2 1 1 3 3 3 0 Golgi transport complex subunit 5 XhlA PF10779.9 EKX52319.1 - 0.34 11.1 7.0 3.6 7.9 0.7 3.0 2 1 1 3 3 3 0 Haemolysin XhlA Occludin_ELL PF07303.13 EKX52319.1 - 0.4 11.4 2.2 16 6.3 0.1 2.9 2 1 0 3 3 3 0 Occludin homology domain FadA PF09403.10 EKX52319.1 - 3.7 8.1 6.5 3.6 8.1 1.6 2.7 2 0 0 2 2 2 0 Adhesion protein FadA Guanylate_cyc PF00211.20 EKX52321.1 - 6.8e-39 133.4 0.0 9.9e-39 132.8 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain GAF_2 PF13185.6 EKX52321.1 - 3.1e-05 24.3 0.0 6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EKX52321.1 - 0.0014 19.3 0.0 0.0029 18.3 0.0 1.6 1 0 0 1 1 1 1 GAF domain Transcrip_act PF04949.13 EKX52322.1 - 7.8e-22 77.8 20.5 7.8e-22 77.8 20.5 1.4 2 0 0 2 2 2 1 Transcriptional activator Glu-tRNAGln PF02686.15 EKX52322.1 - 0.13 12.6 1.6 0.17 12.2 0.4 1.9 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit TMPIT PF07851.13 EKX52322.1 - 0.44 9.7 7.0 0.39 9.9 6.0 1.4 1 1 0 1 1 1 0 TMPIT-like protein Phasin PF05597.11 EKX52322.1 - 0.57 10.2 13.2 0.42 10.6 9.6 2.6 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) ARA70 PF12489.8 EKX52322.1 - 2.7 8.2 6.3 11 6.2 6.3 1.9 1 1 0 1 1 1 0 Nuclear coactivator YabA PF06156.13 EKX52322.1 - 4.6 7.9 10.2 8.4 7.1 2.0 2.6 3 0 0 3 3 3 0 Initiation control protein YabA Abhydrolase_1 PF00561.20 EKX52323.1 - 0.00042 20.0 0.0 0.0014 18.3 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EKX52323.1 - 0.014 16.0 0.0 0.03 14.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EKX52323.1 - 0.041 13.2 0.0 0.079 12.2 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MscS_TM PF12794.7 EKX52323.1 - 0.11 11.3 0.8 0.19 10.6 0.8 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Ephrin_rec_like PF07699.13 EKX52323.1 - 0.15 11.8 32.9 0.03 14.1 9.4 3.7 2 1 1 3 3 3 0 Putative ephrin-receptor like TssN PF17555.2 EKX52323.1 - 0.78 9.1 5.9 1.2 8.4 5.9 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN cEGF PF12662.7 EKX52323.1 - 0.79 9.7 5.1 4.4 7.3 5.1 2.4 1 0 0 1 1 1 0 Complement Clr-like EGF-like UbiA PF01040.18 EKX52323.1 - 0.83 8.9 8.5 1.4 8.2 8.5 1.3 1 0 0 1 1 1 0 UbiA prenyltransferase family WD40 PF00400.32 EKX52326.1 - 6.1e-20 71.2 16.4 1e-07 32.5 0.1 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX52326.1 - 3.4e-08 33.7 0.7 1.1 9.7 0.0 4.5 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX52326.1 - 0.021 13.8 0.0 2.7 6.9 0.0 2.7 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EKX52326.1 - 0.15 11.9 0.0 29 4.5 0.0 3.1 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Gar1 PF04410.14 EKX52327.1 - 7.3e-38 129.8 0.7 7.3e-38 129.8 0.7 2.4 3 0 0 3 3 3 1 Gar1/Naf1 RNA binding region Glycos_transf_2 PF00535.26 EKX52328.1 - 3.6e-13 49.7 0.0 1.9e-06 27.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EKX52328.1 - 8.9e-06 25.7 0.0 0.097 12.5 0.0 2.1 1 1 1 2 2 2 2 Glycosyltransferase like family 2 GTP_EFTU PF00009.27 EKX52330.1 - 1.5e-32 112.7 1.4 3.7e-32 111.5 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EKX52330.1 - 2.8e-15 56.3 0.0 7.4e-15 55.0 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 EKX52330.1 - 3e-09 37.1 0.3 3e-09 37.1 0.3 4.7 4 1 1 5 5 5 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EKX52330.1 - 1.9e-06 27.9 0.1 2.8e-05 24.2 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EKX52330.1 - 3.7e-06 26.7 2.7 0.00025 20.9 2.7 2.8 1 1 0 1 1 1 1 Elongation factor Tu domain 4 tRNA_bind PF01588.20 EKX52330.1 - 9.6e-06 25.6 1.0 3.9e-05 23.7 0.1 2.6 2 0 0 2 2 2 1 Putative tRNA binding domain Roc PF08477.13 EKX52330.1 - 0.016 15.4 0.0 0.04 14.1 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EKX52330.1 - 0.028 14.2 2.7 0.17 11.7 0.0 3.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein K_channel_TID PF07941.11 EKX52330.1 - 8.6 6.9 12.3 30 5.1 12.3 1.9 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain IQ PF00612.27 EKX52331.1 - 2.9e-13 48.3 29.5 0.00014 21.3 0.6 6.4 5 0 0 5 5 5 5 IQ calmodulin-binding motif CCDC142 PF14923.6 EKX52332.1 - 1.5e-09 37.2 0.0 1.5e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Coiled-coil protein 142 Sec15 PF04091.12 EKX52332.1 - 6.1e-05 22.6 0.0 0.0002 20.9 0.0 1.9 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like TPR_1 PF00515.28 EKX52333.1 - 0.0082 15.9 5.7 1.4 8.8 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX52333.1 - 0.035 14.4 3.2 2.4 8.5 0.8 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EKX52333.1 - 0.29 11.4 6.7 6.7 7.1 0.1 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX52333.1 - 0.56 10.8 5.7 3.1 8.4 0.2 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX52333.1 - 1.1 9.6 3.6 2.1 8.8 0.2 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1538 PF07556.11 EKX52334.1 - 6.5e-98 326.2 30.1 2.4e-53 180.6 15.7 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1538) CreA PF05981.12 EKX52336.1 - 1.2e-37 128.8 0.0 1.7e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 CreA protein PsbU PF06514.11 EKX52337.1 - 1.6e-27 95.3 0.2 2.1e-27 95.0 0.2 1.2 1 0 0 1 1 1 1 Photosystem II 12 kDa extrinsic protein (PsbU) HHH_3 PF12836.7 EKX52337.1 - 4.3e-07 30.1 0.0 7.2e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix motif FBPase PF00316.20 EKX52338.1 - 3e-56 189.9 0.4 4.1e-56 189.5 0.4 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain NdhM PF10664.9 EKX52338.1 - 0.017 15.3 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M PPR PF01535.20 EKX52339.1 - 0.0087 16.3 0.2 0.15 12.3 0.8 2.2 2 0 0 2 2 2 1 PPR repeat Utp12 PF04003.12 EKX52340.1 - 0.011 16.0 0.5 0.028 14.7 0.5 1.7 1 0 0 1 1 1 0 Dip2/Utp12 Family RVT_1 PF00078.27 EKX52342.1 - 0.00047 19.8 6.3 0.0066 16.0 0.0 2.5 3 0 0 3 3 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) ORC5_C PF14630.6 EKX52342.1 - 0.021 14.4 0.5 0.021 14.4 0.5 2.7 1 1 2 3 3 1 0 Origin recognition complex (ORC) subunit 5 C-terminus CCSAP PF15748.5 EKX52342.1 - 0.15 12.2 33.7 0.23 11.6 33.7 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated AF-4 PF05110.13 EKX52342.1 - 0.26 9.3 32.9 0.34 9.0 32.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Otopetrin PF03189.13 EKX52342.1 - 0.44 9.3 1.3 0.41 9.4 1.3 1.1 1 0 0 1 1 1 0 Otopetrin PAT1 PF09770.9 EKX52342.1 - 1.8 6.7 43.3 2.3 6.4 43.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Plasmodium_Vir PF05795.11 EKX52342.1 - 2.1 7.7 7.8 2.7 7.3 7.8 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein GREB1 PF15782.5 EKX52342.1 - 2.9 4.9 23.5 3.6 4.6 23.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer OATP PF03137.20 EKX52342.1 - 4 5.6 5.4 6.3 5.0 5.4 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SRP-alpha_N PF04086.13 EKX52342.1 - 6.2 6.7 22.5 9.5 6.0 22.5 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal IER PF05760.12 EKX52342.1 - 7.7 6.7 23.2 11 6.3 23.2 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) Presenilin PF01080.17 EKX52342.1 - 8.4 5.0 25.5 12 4.5 25.5 1.3 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 EKX52342.1 - 9.7 5.9 21.0 18 5.1 21.0 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Myb_DNA-binding PF00249.31 EKX52343.1 - 5.1e-08 33.0 0.3 1.3e-07 31.7 0.3 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX52343.1 - 1.1e-05 25.5 2.5 3.3e-05 24.0 0.1 2.6 3 0 0 3 3 3 1 Myb-like DNA-binding domain HNH_4 PF13395.6 EKX52343.1 - 6.1e-05 22.8 0.1 0.00015 21.6 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease HNH_5 PF14279.6 EKX52343.1 - 0.00027 20.7 0.0 0.00072 19.4 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease SLIDE PF09111.10 EKX52343.1 - 0.016 15.2 1.3 0.034 14.2 0.1 2.1 2 0 0 2 2 2 0 SLIDE HNH PF01844.23 EKX52343.1 - 0.077 13.2 0.3 0.23 11.7 0.3 1.8 1 0 0 1 1 1 0 HNH endonuclease HemY_N PF07219.13 EKX52343.1 - 0.17 12.1 0.3 0.33 11.2 0.3 1.4 1 0 0 1 1 1 0 HemY protein N-terminus TPR_8 PF13181.6 EKX52344.1 - 1.5e-13 49.7 0.1 0.0089 16.2 0.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX52344.1 - 2e-13 49.3 0.1 0.0086 16.1 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EKX52344.1 - 4.6e-13 49.5 0.1 0.00018 21.9 0.0 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX52344.1 - 8.9e-13 48.7 2.7 2.7e-08 34.3 0.0 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX52344.1 - 2.6e-12 46.0 0.0 0.0015 18.2 0.0 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX52344.1 - 1.3e-10 41.2 2.6 0.022 15.6 0.0 4.8 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX52344.1 - 4.7e-09 35.8 0.1 0.024 14.3 0.0 4.2 4 1 1 5 5 5 2 TPR repeat TPR_12 PF13424.6 EKX52344.1 - 2.5e-07 30.9 3.0 0.0032 17.7 0.1 3.8 1 1 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX52344.1 - 7.9e-07 28.7 0.4 0.63 10.2 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX52344.1 - 5.2e-06 26.5 0.0 2.1 8.9 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX52344.1 - 3.1e-05 24.1 0.0 0.024 14.8 0.0 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 EKX52344.1 - 3.6e-05 24.2 1.1 0.32 11.4 0.2 2.6 2 1 0 2 2 2 2 Bacterial transcriptional activator domain TPR_6 PF13174.6 EKX52344.1 - 7.3e-05 23.2 0.8 5.1 7.9 0.1 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX52344.1 - 0.00039 20.5 1.0 0.54 10.4 0.0 2.9 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_15 PF13429.6 EKX52344.1 - 0.00084 18.6 0.1 0.024 13.9 0.0 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat Sec16_C PF12931.7 EKX52344.1 - 0.0029 17.3 0.1 0.033 13.9 0.0 2.0 1 1 0 2 2 2 1 Sec23-binding domain of Sec16 TPR_20 PF14561.6 EKX52344.1 - 0.01 16.1 0.0 5.8 7.3 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX52344.1 - 0.12 12.2 2.4 20 5.2 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EKX52344.1 - 0.13 13.0 6.7 1.5 9.7 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat Methyltransf_11 PF08241.12 EKX52345.1 - 1.7e-13 51.0 0.2 3.9e-13 49.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX52345.1 - 4.5e-13 49.3 0.0 5.6e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX52345.1 - 1.1e-12 48.6 0.0 2.4e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX52345.1 - 1.3e-11 45.0 0.1 2.7e-11 44.0 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX52345.1 - 1.3e-09 38.1 0.0 1.5e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX52345.1 - 0.00052 19.4 0.0 0.00082 18.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EKX52345.1 - 0.0016 18.0 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain N6_N4_Mtase PF01555.18 EKX52345.1 - 0.039 13.6 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 DNA methylase TMEM215 PF15746.5 EKX52345.1 - 0.058 12.9 0.0 0.08 12.4 0.0 1.2 1 0 0 1 1 1 0 TMEM215 family DOT1 PF08123.13 EKX52345.1 - 0.071 12.6 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_16 PF10294.9 EKX52345.1 - 0.076 12.7 0.0 0.27 11.0 0.0 1.7 1 1 0 1 1 1 0 Lysine methyltransferase NUC173 PF08161.12 EKX52346.1 - 4e-40 137.7 0.1 7.8e-39 133.5 0.0 2.6 3 0 0 3 3 3 1 NUC173 domain HEAT PF02985.22 EKX52346.1 - 0.11 12.8 0.4 13 6.4 0.0 4.3 4 1 1 5 5 5 0 HEAT repeat SEN1_N PF12726.7 EKX52346.1 - 0.26 9.5 2.0 0.45 8.7 2.0 1.3 1 0 0 1 1 1 0 SEN1 N terminal Asp PF00026.23 EKX52347.1 - 4.8e-08 32.8 0.0 7.4e-07 28.9 0.0 2.3 1 1 0 2 2 2 1 Eukaryotic aspartyl protease UCH PF00443.29 EKX52348.1 - 2e-58 197.9 1.0 2.3e-58 197.7 1.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EKX52348.1 - 5.4e-29 101.8 7.5 3.2e-28 99.3 7.5 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Med25 PF11232.8 EKX52348.1 - 0.027 14.5 0.1 0.24 11.3 0.0 2.2 2 0 0 2 2 2 0 Mediator complex subunit 25 PTOV activation and synapsin 2 Josephin PF02099.17 EKX52348.1 - 0.038 14.1 0.0 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 Josephin Exo_endo_phos PF03372.23 EKX52349.1 - 2.3e-12 46.9 0.0 3.3e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family OSCP PF00213.18 EKX52350.1 - 0.039 14.1 3.4 1.1 9.3 0.2 2.3 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit ADP_ribosyl_GH PF03747.14 EKX52352.1 - 1.2e-22 81.0 0.0 3.4e-22 79.5 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylglycohydrolase EF-hand_1 PF00036.32 EKX52352.1 - 1.3e-10 40.0 0.7 0.00021 20.6 0.3 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX52352.1 - 6.5e-08 31.9 0.2 0.0016 18.2 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EKX52352.1 - 2.8e-07 29.7 1.3 0.026 14.0 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX52352.1 - 2.7e-06 27.7 0.3 9.4e-06 26.0 0.3 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EKX52352.1 - 0.00044 20.0 1.1 0.024 14.5 0.1 3.3 2 1 1 3 3 3 2 EF-hand domain pair GP24_25 PF17388.2 EKX52352.1 - 0.031 14.3 2.5 0.13 12.2 0.2 2.7 3 0 0 3 3 3 0 Tail assembly gene products 24 & 25 Nse4-Nse3_bdg PF15412.6 EKX52352.1 - 0.077 13.1 0.1 0.31 11.2 0.1 2.0 1 0 0 1 1 1 0 Binding domain of Nse4/EID3 to Nse3-MAGE Lipase_GDSL_2 PF13472.6 EKX52354.1 - 4e-09 37.1 0.0 8.1e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EKX52354.1 - 3.5e-07 30.4 0.0 3.2e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Brix PF04427.18 EKX52355.1 - 4.1e-32 111.8 1.5 5.8e-32 111.4 1.5 1.2 1 0 0 1 1 1 1 Brix domain DUF2517 PF10725.9 EKX52355.1 - 0.077 12.8 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) tRNA_synthFbeta PF17759.1 EKX52357.1 - 2.4e-46 157.9 0.0 3.3e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 EKX52357.1 - 9.4e-32 109.1 1.0 2.1e-31 107.9 0.2 2.0 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 EKX52357.1 - 6.9e-27 94.2 0.0 1.5e-26 93.1 0.0 1.6 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 EKX52357.1 - 4.9e-17 62.0 0.2 1.7e-16 60.2 0.1 2.0 2 0 0 2 2 2 1 tRNA synthetase B5 domain CBFD_NFYB_HMF PF00808.23 EKX52359.1 - 8.8e-22 77.2 0.2 1.1e-21 76.9 0.2 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EKX52359.1 - 0.00026 21.4 0.0 0.00036 20.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 EKX52359.1 - 0.027 14.5 0.0 0.035 14.1 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 EKX52359.1 - 0.039 14.0 0.0 0.081 12.9 0.0 1.5 1 1 1 2 2 2 0 Bromodomain associated GCIP PF13324.6 EKX52359.1 - 0.042 13.5 0.1 0.046 13.3 0.1 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting CENP-T_C PF15511.6 EKX52359.1 - 0.049 13.8 0.0 0.057 13.5 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold DUF1995 PF09353.10 EKX52362.1 - 3.1e-36 125.3 0.0 3.7e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) DUF4457 PF14652.6 EKX52363.1 - 7.4e-152 505.3 0.0 3.7e-111 371.5 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4457) F5_F8_type_C PF00754.25 EKX52363.1 - 0.0012 18.9 0.1 0.48 10.5 0.0 2.9 3 0 0 3 3 3 2 F5/8 type C domain Sad1_UNC PF07738.13 EKX52363.1 - 0.0023 17.9 0.0 0.72 9.9 0.0 3.5 3 0 0 3 3 3 1 Sad1 / UNC-like C-terminal DUF4457 PF14652.6 EKX52364.1 - 7.3e-18 64.9 0.0 1.7e-17 63.7 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4457) EF-hand_6 PF13405.6 EKX52364.1 - 0.0036 17.1 0.3 0.017 15.0 0.3 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 EKX52364.1 - 0.011 15.3 0.2 0.011 15.3 0.2 2.2 2 0 0 2 2 2 0 EF hand EF-hand_5 PF13202.6 EKX52364.1 - 0.011 15.2 0.3 0.011 15.2 0.3 2.4 3 0 0 3 3 3 0 EF hand EF-hand_7 PF13499.6 EKX52364.1 - 1 9.8 13.6 10 6.7 10.6 3.1 2 1 0 2 2 2 0 EF-hand domain pair Kinesin_assoc PF16183.5 EKX52364.1 - 7.2 6.7 7.9 5.4 7.1 3.7 2.5 2 1 0 2 2 2 0 Kinesin-associated Cys_Met_Meta_PP PF01053.20 EKX52365.1 - 6e-51 173.1 0.0 6.7e-51 173.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EKX52365.1 - 7.5e-10 38.3 0.0 9.1e-10 38.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EKX52365.1 - 7.7e-05 22.0 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GDC-P PF02347.16 EKX52365.1 - 0.16 10.8 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein SYS1 PF09801.9 EKX52366.1 - 4.7e-32 111.1 7.5 5.3e-32 111.0 7.5 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Pkinase_Tyr PF07714.17 EKX52367.1 - 2.8e-67 226.7 0.0 3.6e-67 226.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX52367.1 - 4.3e-32 111.5 0.0 6.1e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain zf-C3HC4_3 PF13920.6 EKX52367.1 - 3.6e-09 36.3 6.7 8.3e-09 35.2 6.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX52367.1 - 0.00013 21.7 8.7 0.00033 20.5 8.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 AA_permease_N PF08403.10 EKX52367.1 - 0.086 12.3 0.1 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 Amino acid permease N-terminal Vpu PF00558.19 EKX52367.1 - 0.16 11.8 0.4 16 5.3 0.1 2.4 2 0 0 2 2 2 0 Vpu protein zf-RING_2 PF13639.6 EKX52367.1 - 0.2 12.0 9.6 0.54 10.6 9.6 1.8 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 EKX52367.1 - 0.37 10.8 7.1 0.98 9.4 7.1 1.7 1 0 0 1 1 1 0 zinc-RING finger domain ExoD PF06055.12 EKX52368.1 - 5.1e-19 68.3 5.9 5.1e-19 68.3 5.9 1.5 2 0 0 2 2 2 1 Exopolysaccharide synthesis, ExoD MMR_HSR1 PF01926.23 EKX52370.1 - 9.4e-22 77.2 0.0 1.7e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase KH_2 PF07650.17 EKX52370.1 - 1.1e-08 34.8 0.1 1.9e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 KH domain FeoB_N PF02421.18 EKX52370.1 - 3.6e-08 33.1 0.0 6.1e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EKX52370.1 - 4.3e-07 30.2 0.2 5.2e-05 23.4 0.2 2.3 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 EKX52370.1 - 2.9e-05 24.0 0.0 0.00058 19.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 EKX52370.1 - 5.5e-05 22.6 0.0 8.9e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 AIG1 family FtsK_SpoIIIE PF01580.18 EKX52370.1 - 0.0059 16.0 0.0 0.0096 15.3 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family PduV-EutP PF10662.9 EKX52370.1 - 0.0076 16.0 0.0 1 9.1 0.0 2.7 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 EKX52370.1 - 0.015 15.8 0.2 0.029 14.9 0.2 1.4 1 0 0 1 1 1 0 ABC transporter cobW PF02492.19 EKX52370.1 - 0.017 14.7 0.1 4.2 6.9 0.0 2.4 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 EKX52370.1 - 0.023 14.4 0.0 0.087 12.6 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_28 PF13521.6 EKX52370.1 - 0.028 14.7 0.0 0.046 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 EKX52370.1 - 0.032 13.7 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EKX52370.1 - 0.053 13.1 0.1 0.23 11.0 0.2 2.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PCO_ADO PF07847.12 EKX52371.1 - 2.7e-38 131.4 0.0 4.4e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 PCO_ADO NOD2_WH PF17779.1 EKX52371.1 - 0.021 15.2 0.0 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 NOD2 winged helix domain Cupin_2 PF07883.11 EKX52371.1 - 0.15 11.8 0.0 0.7 9.7 0.0 2.0 2 0 0 2 2 2 0 Cupin domain RRM_1 PF00076.22 EKX52372.1 - 4.2e-12 45.7 0.6 5.2e-06 26.2 0.2 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) La PF05383.17 EKX52372.1 - 1.5e-07 31.4 0.0 4.3e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 La domain RRM_3 PF08777.11 EKX52372.1 - 0.00067 19.7 0.2 0.013 15.5 0.0 2.5 2 0 0 2 2 2 1 RNA binding motif DUF4523 PF15023.6 EKX52372.1 - 0.027 14.3 0.0 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Bud13 PF09736.9 EKX52373.1 - 4.5e-12 46.6 3.5 8.9e-12 45.6 3.5 1.6 1 1 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex GCD14 PF08704.10 EKX52374.1 - 2.7e-24 86.2 0.0 2.5e-12 47.0 0.0 2.8 2 1 1 3 3 3 2 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 EKX52374.1 - 3.9e-06 26.8 0.0 5.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EKX52374.1 - 4.2e-05 23.4 0.0 0.00011 22.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX52374.1 - 0.014 16.1 0.0 0.26 12.0 0.0 2.2 1 1 1 2 2 2 0 Methyltransferase domain T3SS_ExsE PF18286.1 EKX52374.1 - 0.039 13.9 2.5 0.12 12.3 0.1 2.5 3 0 0 3 3 3 0 Type III secretion system ExsE GCD14_N PF14801.6 EKX52374.1 - 0.89 9.4 4.9 0.71 9.8 0.9 2.2 1 1 1 2 2 2 0 tRNA methyltransferase complex GCD14 subunit N-term DUF1618 PF07762.14 EKX52375.1 - 0.22 12.1 1.5 4.2 8.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1618) Syntaxin PF00804.25 EKX52376.1 - 6.5e-38 130.4 10.3 6.5e-38 130.4 10.3 1.6 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 EKX52376.1 - 2.5e-13 49.8 0.4 6.1e-13 48.5 0.3 1.8 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 EKX52376.1 - 8.4e-05 22.9 13.1 0.0006 20.1 2.0 3.0 1 1 2 3 3 3 2 Syntaxin-like protein DUF5344 PF17279.2 EKX52376.1 - 0.0067 17.0 12.4 0.042 14.4 2.5 3.3 2 2 0 2 2 2 2 Family of unknown function (DUF5344) T2SSF PF00482.23 EKX52376.1 - 0.054 13.5 2.1 0.11 12.4 1.3 2.0 1 1 0 2 2 2 0 Type II secretion system (T2SS), protein F Arc_PepC_II PF06847.11 EKX52376.1 - 0.12 12.9 0.4 0.12 12.9 0.4 2.5 2 2 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Synaptobrevin PF00957.21 EKX52376.1 - 0.16 11.7 4.8 0.063 13.1 1.5 2.0 2 0 0 2 2 2 0 Synaptobrevin SKA1 PF07160.12 EKX52376.1 - 5.5 6.8 12.3 0.31 10.8 3.6 2.2 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Occludin_ELL PF07303.13 EKX52376.1 - 6.3 7.6 12.9 1.2 9.9 1.0 3.0 2 1 0 3 3 3 0 Occludin homology domain HLH PF00010.26 EKX52377.1 - 2e-09 37.3 1.6 3.3e-09 36.6 1.6 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ASH PF15780.5 EKX52378.1 - 2.5e-27 94.9 11.1 0.0075 16.4 0.2 10.6 11 0 0 11 11 11 8 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 EKX52378.1 - 1.1e-17 63.8 4.0 0.003 17.4 0.4 8.3 7 1 1 8 8 8 4 MSP (Major sperm protein) domain PapD-like PF14874.6 EKX52378.1 - 1.6e-14 53.9 2.4 0.0023 18.0 0.0 5.8 5 0 0 5 5 5 4 Flagellar-associated PapD-like DUF1573 PF07610.11 EKX52378.1 - 6.6e-14 51.7 10.4 5.5e-07 29.5 0.0 8.8 10 1 0 10 10 10 3 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 EKX52378.1 - 1.3e-05 25.4 10.2 5 7.4 0.0 7.2 8 0 0 8 8 8 2 Transmembrane protein 131-like MYCBPAP PF14646.6 EKX52378.1 - 0.0014 17.7 0.5 2.2 7.1 0.0 3.7 2 1 0 3 3 3 2 MYCBP-associated protein family DUF5001 PF16392.5 EKX52378.1 - 0.078 12.9 0.0 11 6.0 0.0 3.9 4 0 0 4 4 4 0 Ig-like domain Nse4_C PF08743.10 EKX52379.1 - 2.5e-14 53.3 0.1 2.5e-14 53.3 0.1 2.2 3 0 0 3 3 3 1 Nse4 C-terminal ThiF PF00899.21 EKX52381.1 - 1.4e-23 83.6 0.7 9.7e-20 71.0 0.2 2.3 1 1 1 2 2 2 2 ThiF family F5_F8_type_C PF00754.25 EKX52381.1 - 3.6e-11 43.3 0.0 9.3e-11 41.9 0.0 1.8 1 1 0 1 1 1 1 F5/8 type C domain Rhodanese PF00581.20 EKX52381.1 - 6.3e-07 29.9 0.1 1.8e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain I_LWEQ PF01608.17 EKX52381.1 - 0.024 14.9 2.0 0.11 12.8 0.0 2.4 2 0 0 2 2 2 0 I/LWEQ domain DUF4140 PF13600.6 EKX52381.1 - 0.06 13.8 3.2 2.7 8.5 0.1 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Allantoicase PF03561.15 EKX52381.1 - 0.066 13.2 0.4 0.2 11.7 0.0 1.9 2 0 0 2 2 2 0 Allantoicase repeat Myb_DNA-binding PF00249.31 EKX52383.1 - 1.2e-09 38.2 1.3 3.4e-09 36.8 0.2 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX52383.1 - 1e-07 32.1 0.4 9.5e-07 29.0 0.5 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 EKX52383.1 - 0.023 14.7 2.9 0.23 11.6 0.2 3.5 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain GPS PF01825.21 EKX52384.1 - 9.6 6.8 11.2 1.5 9.4 3.1 2.5 2 0 0 2 2 2 0 GPCR proteolysis site, GPS, motif UQ_con PF00179.26 EKX52385.1 - 1.8e-51 173.5 0.0 2e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EKX52385.1 - 0.0013 19.0 0.0 0.0013 19.0 0.0 1.3 1 0 0 1 1 1 1 RWD domain Oscp1 PF10188.9 EKX52386.1 - 8.8e-52 175.7 5.2 1e-51 175.5 5.2 1.0 1 0 0 1 1 1 1 Organic solute transport protein 1 DUF1002 PF06207.11 EKX52386.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1002) Kinesin PF00225.23 EKX52388.1 - 5.2e-34 117.7 0.0 7.9e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX52388.1 - 1.9e-09 37.6 0.0 3.7e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding LSM PF01423.22 EKX52389.1 - 1.2e-17 63.4 0.1 1.3e-17 63.2 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EKX52389.1 - 0.0017 18.4 0.1 0.0021 18.1 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Thiol_cytolysin PF01289.19 EKX52389.1 - 0.11 11.4 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Thiol-activated cytolysin ADP_ribosyl_GH PF03747.14 EKX52390.1 - 2.9e-43 148.7 0.2 4.2e-43 148.1 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Gly-zipper_YMGG PF13441.6 EKX52390.1 - 0.033 13.9 8.3 0.39 10.5 3.0 2.6 2 0 0 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.6 EKX52390.1 - 6.1 6.7 11.3 0.24 11.2 3.1 2.3 2 0 0 2 2 2 0 Glycine-zipper domain Gly-zipper_Omp PF13488.6 EKX52390.1 - 7.7 6.6 11.4 2.1 8.4 3.5 2.6 2 0 0 2 2 2 0 Glycine zipper Adaptin_N PF01602.20 EKX52394.1 - 4.9e-120 401.5 5.4 6.6e-120 401.1 5.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EKX52394.1 - 2.6e-13 50.3 7.7 2.3e-10 40.8 0.4 3.5 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EKX52394.1 - 3.9e-07 30.4 0.3 0.088 13.2 0.0 5.1 3 1 1 5 5 5 1 HEAT repeats HEAT PF02985.22 EKX52394.1 - 4.1e-06 26.6 5.5 3.7 8.1 0.0 6.7 7 0 0 7 7 7 1 HEAT repeat RTP1_C1 PF10363.9 EKX52394.1 - 0.02 15.1 0.3 10 6.3 0.0 3.7 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 DM4_12 PF07841.13 EKX52394.1 - 0.045 14.4 0.1 1.5 9.5 0.0 3.0 2 0 0 2 2 2 0 DM4/DM12 family Alpha_adaptinC2 PF02883.20 EKX52394.1 - 0.073 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 Adaptin C-terminal domain V-ATPase_H_C PF11698.8 EKX52394.1 - 0.1 12.7 1.1 2.8 8.1 0.1 3.6 3 1 0 3 3 3 0 V-ATPase subunit H Coatamer_beta_C PF07718.12 EKX52394.1 - 0.11 12.4 0.1 0.11 12.4 0.1 3.1 3 0 0 3 3 3 0 Coatomer beta C-terminal region DUF936 PF06075.12 EKX52394.1 - 0.43 9.5 27.7 0.62 8.9 27.7 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Sec1 PF00995.23 EKX52395.1 - 4.1e-75 254.2 0.4 7.6e-41 141.0 0.1 2.0 2 0 0 2 2 2 2 Sec1 family DUF2732 PF10809.8 EKX52395.1 - 0.019 14.8 0.1 0.068 13.0 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) RNA_pol_Rpb6 PF01192.22 EKX52395.1 - 0.13 12.2 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb6 Sec23_trunk PF04811.15 EKX52396.1 - 4.1e-17 62.6 0.0 1.3e-16 60.9 0.0 1.8 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 EKX52396.1 - 1.6e-08 34.5 1.2 3.2e-08 33.5 1.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 EKX52396.1 - 1.6e-07 32.0 0.0 3.5e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EKX52396.1 - 1.1e-06 28.4 0.1 3.6e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain WXG100 PF06013.12 EKX52396.1 - 0.063 13.5 0.3 0.14 12.4 0.3 1.5 1 0 0 1 1 1 0 Proteins of 100 residues with WXG PPV_E1_N PF00524.18 EKX52396.1 - 0.12 12.8 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 E1 Protein, N terminal domain zinc_ribbon_10 PF10058.9 EKX52396.1 - 0.13 12.0 2.0 0.28 10.9 2.0 1.6 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-RanBP PF00641.18 EKX52396.1 - 0.14 11.5 2.9 0.21 11.0 0.2 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Nudix_N_2 PF14803.6 EKX52396.1 - 0.28 11.2 1.4 1.5 8.8 0.3 2.6 2 0 0 2 2 2 0 Nudix N-terminal Ribosomal_L7Ae PF01248.26 EKX52397.1 - 5.3e-25 87.0 0.4 7.3e-25 86.5 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Mito_carr PF00153.27 EKX52398.1 - 3.1e-58 193.7 0.4 1.5e-18 66.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L19e PF01280.20 EKX52399.1 - 9.3e-63 210.6 10.2 9.3e-63 210.6 10.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L19e HMw1_D2 PF18254.1 EKX52399.1 - 0.099 13.0 0.1 0.19 12.1 0.1 1.4 1 0 0 1 1 1 0 HMW1 domain 2 DDE_Tnp_1_7 PF13843.6 EKX52400.1 - 2.7e-18 66.4 0.0 3.2e-18 66.1 0.0 1.0 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_1 PF01609.21 EKX52400.1 - 0.0049 16.6 0.0 0.0053 16.4 0.0 1.1 1 0 0 1 1 1 1 Transposase DDE domain XhlA PF10779.9 EKX52403.1 - 0.00081 19.5 9.2 0.17 12.1 0.2 4.0 3 1 1 4 4 4 1 Haemolysin XhlA DUF4140 PF13600.6 EKX52403.1 - 0.0024 18.2 6.9 0.69 10.4 0.2 3.2 2 1 1 3 3 3 2 N-terminal domain of unknown function (DUF4140) HSBP1 PF06825.12 EKX52403.1 - 0.0033 17.3 10.3 13 5.7 0.7 5.4 5 1 0 5 5 5 0 Heat shock factor binding protein 1 FlaC_arch PF05377.11 EKX52403.1 - 0.0042 17.4 4.9 0.78 10.2 0.8 3.1 3 1 0 3 3 2 1 Flagella accessory protein C (FlaC) ABC_tran_CTD PF16326.5 EKX52403.1 - 0.0044 17.3 16.8 0.65 10.3 5.0 4.3 2 2 2 4 4 4 2 ABC transporter C-terminal domain DUF4988 PF16378.5 EKX52403.1 - 0.01 15.6 0.6 1.4 8.6 0.0 3.1 3 1 0 3 3 2 1 Domain of unknown function Dynamitin PF04912.14 EKX52403.1 - 0.012 14.9 10.3 8.5 5.6 3.5 3.3 1 1 1 2 2 2 0 Dynamitin DUF4407 PF14362.6 EKX52403.1 - 0.017 14.5 0.5 0.037 13.4 0.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Jnk-SapK_ap_N PF09744.9 EKX52403.1 - 0.017 15.4 1.4 0.017 15.4 1.4 2.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Occludin_ELL PF07303.13 EKX52403.1 - 0.017 15.8 1.5 5.3 7.8 0.1 2.5 2 0 0 2 2 2 0 Occludin homology domain DUF1664 PF07889.12 EKX52403.1 - 0.029 14.4 2.2 3.2 7.8 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Phasin PF05597.11 EKX52403.1 - 0.03 14.3 5.0 0.11 12.5 0.2 3.1 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF724 PF05266.14 EKX52403.1 - 0.038 13.8 4.4 0.72 9.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) NPV_P10 PF05531.12 EKX52403.1 - 0.038 14.4 0.2 13 6.4 0.0 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ACCA PF03255.14 EKX52403.1 - 0.04 13.8 5.1 0.28 11.0 0.4 2.4 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF2730 PF10805.8 EKX52403.1 - 0.048 13.8 6.4 0.63 10.2 0.5 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF2730) Spc7 PF08317.11 EKX52403.1 - 0.049 12.5 5.9 1.1 8.1 0.5 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein PspA_IM30 PF04012.12 EKX52403.1 - 0.084 12.4 4.8 1.1 8.8 0.3 2.3 2 0 0 2 2 2 0 PspA/IM30 family ADIP PF11559.8 EKX52403.1 - 0.14 12.2 3.1 2 8.5 0.5 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding GAS PF13851.6 EKX52403.1 - 0.16 11.3 7.6 1.7 8.0 0.7 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TSNAXIP1_N PF15739.5 EKX52403.1 - 0.16 12.3 2.4 11 6.5 0.2 2.6 2 1 0 2 2 2 0 Translin-associated factor X-interacting N-terminus DUF16 PF01519.16 EKX52403.1 - 0.21 12.1 5.4 5.9 7.4 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function DUF16 Efg1 PF10153.9 EKX52403.1 - 0.23 11.8 7.6 2.9 8.3 1.1 2.4 2 0 0 2 2 2 0 rRNA-processing protein Efg1 Vps5 PF09325.10 EKX52403.1 - 0.26 10.8 4.1 7.1 6.1 0.2 2.3 2 0 0 2 2 2 0 Vps5 C terminal like Pox_A_type_inc PF04508.12 EKX52403.1 - 0.28 11.1 19.3 1.1 9.3 0.0 5.5 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat Med9 PF07544.13 EKX52403.1 - 0.32 11.1 7.3 0.15 12.2 1.8 2.5 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 TPR_MLP1_2 PF07926.12 EKX52403.1 - 0.32 11.1 11.7 2.8 8.0 3.9 2.7 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein PCRF PF03462.18 EKX52403.1 - 0.33 10.8 6.5 0.91 9.4 1.4 2.1 1 1 1 2 2 2 0 PCRF domain Uds1 PF15456.6 EKX52403.1 - 0.33 11.1 5.4 1.9 8.7 5.3 2.2 1 1 0 1 1 1 0 Up-regulated During Septation SPT16 PF08644.11 EKX52403.1 - 0.34 11.1 1.6 10 6.3 0.1 2.2 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) DUF241 PF03087.14 EKX52403.1 - 0.38 10.5 3.2 2.6 7.8 0.1 2.6 2 1 0 2 2 2 0 Arabidopsis protein of unknown function Sugarporin_N PF11471.8 EKX52403.1 - 0.41 10.6 13.0 1.9 8.5 0.0 4.9 4 1 1 5 5 5 0 Maltoporin periplasmic N-terminal extension PAXX PF15384.6 EKX52403.1 - 0.62 9.7 2.5 4.2 7.0 0.1 2.5 2 1 1 3 3 3 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 YgaB PF14182.6 EKX52403.1 - 0.64 10.5 5.8 1.9 8.9 0.4 2.5 2 1 0 2 2 2 0 YgaB-like protein FUSC PF04632.12 EKX52403.1 - 0.64 8.5 4.1 3.7 6.0 4.1 1.9 1 1 0 1 1 1 0 Fusaric acid resistance protein family Alpha-E PF04168.12 EKX52403.1 - 0.69 9.6 5.3 4.4 7.0 0.2 2.1 2 0 0 2 2 2 0 A predicted alpha-helical domain with a conserved ER motif. CLZ PF16526.5 EKX52403.1 - 0.89 10.0 15.8 7.5 7.0 2.3 4.1 2 2 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2408 PF10303.9 EKX52403.1 - 1 9.9 6.8 7.7 7.1 1.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DUF5082 PF16888.5 EKX52403.1 - 1.4 9.2 5.5 5.1 7.4 0.6 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Exonuc_VII_L PF02601.15 EKX52403.1 - 1.5 8.3 4.2 9.2 5.7 4.2 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit Spc24 PF08286.11 EKX52403.1 - 1.5 9.1 5.8 14 6.0 1.1 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 GARP PF16731.5 EKX52403.1 - 1.5 8.5 4.7 4 7.1 0.5 2.3 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma Rootletin PF15035.6 EKX52403.1 - 2.8 7.9 8.2 1.2e+02 2.7 8.2 2.4 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion COG2 PF06148.11 EKX52403.1 - 3.2 7.9 6.0 3.9 7.6 0.7 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Matrilin_ccoil PF10393.9 EKX52403.1 - 4.3 7.3 13.2 25 4.8 0.0 4.8 4 2 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin Vac_Fusion PF02346.16 EKX52403.1 - 5.3 6.7 6.8 16 5.2 2.7 3.0 2 2 1 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 DUF2802 PF10975.8 EKX52403.1 - 5.7 7.2 11.8 56 4.0 3.6 4.8 2 2 1 3 3 3 0 Protein of unknown function (DUF2802) MPS2 PF17060.5 EKX52403.1 - 6.2 6.0 7.3 3.4 6.8 0.8 2.1 2 0 0 2 2 2 0 Monopolar spindle protein 2 DUF4349 PF14257.6 EKX52403.1 - 6.5 6.1 6.0 18 4.7 1.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4349) TolA_bind_tri PF16331.5 EKX52403.1 - 7 6.8 10.7 5.6 7.1 4.3 3.2 2 2 0 3 3 2 0 TolA binding protein trimerisation GreA_GreB_N PF03449.15 EKX52403.1 - 7.8 6.7 19.5 19 5.5 3.4 5.4 2 2 2 4 4 4 0 Transcription elongation factor, N-terminal DUF812 PF05667.11 EKX52403.1 - 8 5.2 8.7 1.8 7.4 1.0 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF812) Cnn_1N PF07989.11 EKX52403.1 - 8.5 6.6 10.6 25 5.1 0.8 3.3 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 M PF02370.16 EKX52403.1 - 8.5 7.3 5.9 73 4.5 0.0 3.6 3 0 0 3 3 3 0 M protein repeat Ribosomal_L29 PF00831.23 EKX52404.1 - 1.2e-20 73.2 2.2 1.2e-20 73.2 2.2 2.5 2 1 0 2 2 2 1 Ribosomal L29 protein DUF373 PF04123.13 EKX52404.1 - 0.05 13.0 0.1 0.058 12.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) PRP1_N PF06424.12 EKX52404.1 - 0.2 12.0 4.7 0.17 12.3 0.6 2.0 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal RBM39linker PF15519.6 EKX52404.1 - 0.88 10.7 3.2 3.1 9.0 0.3 2.1 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein BPL_LplA_LipB PF03099.19 EKX52405.1 - 3.2e-10 40.0 0.0 5.1e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Thiolase_N PF00108.23 EKX52406.1 - 1.8e-07 30.8 0.0 2.5e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EKX52406.1 - 0.066 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III RrnaAD PF00398.20 EKX52407.1 - 1.6e-26 92.9 0.0 2.6e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 EKX52407.1 - 0.0018 17.8 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_28 PF02636.17 EKX52407.1 - 0.068 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Prefoldin_2 PF01920.20 EKX52409.1 - 0.02 14.8 0.5 0.65 10.0 0.1 2.3 1 1 1 2 2 2 0 Prefoldin subunit Nrap_D2 PF17403.2 EKX52410.1 - 0.013 15.3 0.1 0.018 14.8 0.1 1.2 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain VCBS PF13517.6 EKX52411.1 - 1.2e-20 73.8 18.9 1e-08 35.7 0.3 5.2 4 1 1 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EKX52411.1 - 7.4e-11 42.0 12.0 0.052 13.7 0.1 5.7 5 0 0 5 5 5 5 FG-GAP repeat TcdB_toxin_midN PF12256.8 EKX52411.1 - 0.01 15.2 0.1 6 6.2 0.0 3.5 3 0 0 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region DUF5538 PF17692.1 EKX52411.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5538) DUF4269 PF14091.6 EKX52412.1 - 0.18 12.1 0.0 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) Rhomboid PF01694.22 EKX52415.1 - 1.8e-31 109.2 19.7 1.8e-31 109.2 19.7 2.0 2 0 0 2 2 2 1 Rhomboid family DUF1751 PF08551.10 EKX52415.1 - 0.0017 18.9 0.3 0.0017 18.9 0.3 2.9 3 1 0 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) Toxin_16 PF07945.11 EKX52415.1 - 0.2 11.5 6.9 0.41 10.6 6.9 1.4 1 0 0 1 1 1 0 Janus-atracotoxin FA_desaturase PF00487.24 EKX52416.1 - 1e-38 133.7 22.3 1.4e-38 133.2 22.3 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EKX52416.1 - 8.7e-08 32.2 0.0 1.9e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DIOX_N PF14226.6 EKX52419.1 - 2.4e-07 31.5 0.2 4.2e-07 30.7 0.2 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DUF4079 PF13301.6 EKX52420.1 - 0.002 18.3 1.1 0.0037 17.4 0.7 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF4079) Luteo_PO PF04662.13 EKX52420.1 - 0.015 15.0 0.3 0.026 14.2 0.3 1.4 1 0 0 1 1 1 0 Luteovirus P0 protein DUF981 PF06168.11 EKX52420.1 - 0.015 15.2 1.5 0.022 14.7 1.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF981) VPS9 PF02204.18 EKX52421.1 - 5.9e-26 90.7 0.0 1.2e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EKX52421.1 - 2.1e-08 34.3 0.1 6.3e-08 32.8 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) L27_1 PF09058.10 EKX52421.1 - 0.19 11.7 0.6 2.7 8.0 0.1 2.6 2 0 0 2 2 2 0 L27_1 Peptidase_M28 PF04389.17 EKX52422.1 - 9.8e-26 90.7 0.0 1.8e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EKX52422.1 - 0.08 12.6 0.0 0.25 11.0 0.0 1.7 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 Imm17 PF15562.6 EKX52422.1 - 0.099 12.5 3.1 0.34 10.8 3.1 2.0 1 0 0 1 1 1 0 Immunity protein 17 Cyclin PF08613.11 EKX52424.1 - 3.3e-22 79.6 0.0 4.2e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EKX52424.1 - 0.0035 17.1 0.0 0.006 16.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ppx-GppA PF02541.16 EKX52425.1 - 1.1e-11 44.7 0.1 1.5e-11 44.2 0.1 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family ING PF12998.7 EKX52426.1 - 1.7e-17 63.9 4.7 2.1e-17 63.6 4.7 1.1 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Spc7 PF08317.11 EKX52426.1 - 0.07 12.0 3.7 0.1 11.4 3.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Hemagglutinin PF00509.18 EKX52426.1 - 0.088 11.2 1.9 0.1 11.0 1.9 1.1 1 0 0 1 1 1 0 Haemagglutinin DUF1664 PF07889.12 EKX52426.1 - 0.14 12.2 3.1 2.3 8.3 2.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 EKX52426.1 - 0.17 11.4 4.4 4.3 6.8 2.3 2.0 1 1 1 2 2 2 0 Exonuclease VII, large subunit NPV_P10 PF05531.12 EKX52426.1 - 4.7 7.7 7.9 11 6.5 2.9 2.5 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Fve PF09259.11 EKX52427.1 - 0.039 14.1 0.0 0.062 13.5 0.0 1.2 1 0 0 1 1 1 0 Fungal immunomodulatory protein Fve Pkinase_Tyr PF07714.17 EKX52428.1 - 6.7e-62 209.1 0.0 7.9e-62 208.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX52428.1 - 6.8e-30 104.3 0.0 8.6e-30 104.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain zf-C3HC4_3 PF13920.6 EKX52428.1 - 2e-09 37.1 7.7 3.9e-09 36.2 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX52428.1 - 2.3e-06 27.4 9.7 5.1e-06 26.3 9.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EKX52428.1 - 0.056 13.8 9.6 0.14 12.5 9.6 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 EKX52428.1 - 0.098 12.6 6.9 0.24 11.4 6.9 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Kinase-like PF14531.6 EKX52428.1 - 0.38 10.0 2.2 1.8 7.8 2.2 1.9 1 1 0 1 1 1 0 Kinase-like BIR PF00653.21 EKX52429.1 - 1.1e-15 58.0 0.3 2.9e-15 56.6 0.3 1.8 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain C2 PF00168.30 EKX52429.1 - 0.017 15.4 0.0 1.2 9.4 0.0 3.4 3 0 0 3 3 3 0 C2 domain DUF4746 PF15928.5 EKX52429.1 - 0.19 11.1 7.1 0.36 10.2 7.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) HSA PF07529.13 EKX52429.1 - 0.84 10.0 5.5 1.7 9.0 3.4 2.4 2 0 0 2 2 2 0 HSA BioT2 PF15368.6 EKX52429.1 - 1.5 8.8 8.6 2.6 8.0 8.6 1.3 1 0 0 1 1 1 0 Spermatogenesis family BioT2 BSP_II PF05432.11 EKX52429.1 - 1.7 8.3 15.8 1.2 8.8 11.6 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) AAA_11 PF13086.6 EKX52429.1 - 2.3 8.0 9.2 4.9 6.9 0.3 2.3 2 0 0 2 2 2 0 AAA domain MCU PF04678.13 EKX52429.1 - 3.2 7.8 4.9 7.8 6.6 4.9 1.6 1 0 0 1 1 1 0 Mitochondrial calcium uniporter PPL5 PF18168.1 EKX52429.1 - 8.8 5.5 8.9 5 6.3 2.3 2.2 2 0 0 2 2 2 0 Prim-pol family 5 H2TH PF06831.14 EKX52430.1 - 1.3e-17 63.6 0.0 2.5e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain SAP PF02037.27 EKX52430.1 - 6.9e-11 41.6 0.9 1.2e-10 40.9 0.9 1.4 1 0 0 1 1 1 1 SAP domain Fapy_DNA_glyco PF01149.24 EKX52430.1 - 1.5e-06 28.8 0.0 3.6e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain HeH PF12949.7 EKX52430.1 - 0.097 12.4 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 HeH/LEM domain LEM PF03020.15 EKX52430.1 - 0.41 10.3 1.4 3.7 7.2 0.2 2.3 2 0 0 2 2 2 0 LEM domain GATase PF00117.28 EKX52433.1 - 1.9e-13 50.6 0.0 2.1e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EKX52433.1 - 8.1e-06 25.7 0.1 3.2e-05 23.8 0.1 1.9 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.14 EKX52433.1 - 0.0028 17.3 0.0 0.0032 17.1 0.0 1.1 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain TFIIA PF03153.13 EKX52436.1 - 5.4 6.9 24.3 6.6 6.6 24.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lipase_3 PF01764.25 EKX52437.1 - 3.9e-34 117.5 0.0 5.6e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 EKX52437.1 - 1.9e-05 24.3 0.0 0.14 11.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 EKX52437.1 - 0.0052 16.1 0.1 0.0081 15.4 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EKX52437.1 - 0.17 11.6 0.1 0.63 9.8 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family SNARE PF05739.19 EKX52438.1 - 0.01 15.8 5.3 15 5.7 0.1 3.4 3 0 0 3 3 3 0 SNARE domain DUF1664 PF07889.12 EKX52438.1 - 0.094 12.8 0.5 11 6.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SQS_PSY PF00494.19 EKX52439.1 - 7e-40 137.2 0.1 8.6e-40 136.9 0.1 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase APS_kinase PF01583.20 EKX52440.1 - 1.5e-67 226.4 0.0 2e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 EKX52440.1 - 1.3e-07 31.9 0.0 2.1e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EKX52440.1 - 5.8e-06 26.9 0.1 9.9e-06 26.1 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EKX52440.1 - 0.012 15.3 1.2 0.021 14.6 1.2 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EKX52440.1 - 0.018 15.6 0.0 0.023 15.2 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 EKX52440.1 - 0.19 11.0 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AhpC-TSA_2 PF13911.6 EKX52441.1 - 5.6e-09 36.1 0.0 3.3e-05 24.0 0.0 2.3 1 1 1 2 2 2 2 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EKX52441.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family TIG PF01833.24 EKX52442.1 - 1.4e-62 207.8 41.2 9.7e-11 41.6 0.0 9.5 9 0 0 9 9 9 9 IPT/TIG domain Filamin PF00630.19 EKX52443.1 - 8.3e-66 219.3 0.0 3.4e-07 31.0 0.0 11.7 11 1 0 11 11 11 9 Filamin/ABP280 repeat Invasin_D3 PF09134.10 EKX52443.1 - 2.2e-05 24.7 23.8 1.6 9.1 0.0 9.1 9 1 1 10 10 10 4 Invasin, domain 3 YtkA PF13115.6 EKX52443.1 - 0.00032 21.2 0.2 74 4.1 0.0 6.7 8 0 0 8 8 8 0 YtkA-like Filamin PF00630.19 EKX52444.1 - 7.1e-22 78.2 0.0 4.6e-08 33.8 0.0 3.1 2 1 1 3 3 3 3 Filamin/ABP280 repeat Invasin_D3 PF09134.10 EKX52444.1 - 2.5e-08 34.1 2.7 0.014 15.7 0.3 3.5 2 1 2 4 4 4 3 Invasin, domain 3 He_PIG PF05345.12 EKX52444.1 - 1.8 8.8 7.5 14 6.0 0.5 3.3 3 1 1 4 4 4 0 Putative Ig domain SNARE_assoc PF09335.11 EKX52447.1 - 4.5e-08 33.6 3.6 9.5e-08 32.6 3.6 1.6 1 1 0 1 1 1 1 SNARE associated Golgi protein GSCFA PF08885.11 EKX52447.1 - 0.24 11.0 0.0 0.36 10.4 0.0 1.2 1 0 0 1 1 1 0 GSCFA family Autophagy_act_C PF03987.15 EKX52448.1 - 4.6e-12 46.3 1.5 1.8e-11 44.4 1.0 2.2 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Tetraspanin PF00335.20 EKX52449.1 - 1.3e-14 54.4 24.1 1.1e-13 51.4 24.1 2.0 1 1 0 1 1 1 1 Tetraspanin family DUF2569 PF10754.9 EKX52449.1 - 0.074 13.5 5.4 0.053 14.0 2.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) SLATT_fungal PF18142.1 EKX52449.1 - 0.23 11.4 2.0 0.2 11.7 0.4 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain DUF2207 PF09972.9 EKX52449.1 - 2 7.1 5.2 14 4.3 5.2 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) KH_1 PF00013.29 EKX52450.1 - 2.9e-40 135.9 7.9 4.9e-15 55.1 1.3 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EKX52450.1 - 2.4e-12 46.5 5.2 2.2e-06 27.4 0.1 3.2 3 0 0 3 3 3 2 KH domain KH_4 PF13083.6 EKX52450.1 - 5e-09 35.9 3.7 0.026 14.4 0.1 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EKX52450.1 - 0.029 14.4 4.0 5 7.3 0.1 3.3 3 0 0 3 3 3 0 NusA-like KH domain E2R135 PF11570.8 EKX52450.1 - 0.033 14.5 0.0 0.09 13.1 0.0 1.7 2 0 0 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 C2 PF00168.30 EKX52452.1 - 2.5e-17 63.1 0.0 5.8e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 C2 domain FAM176 PF14851.6 EKX52452.1 - 0.0052 16.4 0.5 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 FAM176 family AMP-binding PF00501.28 EKX52453.1 - 3.1e-42 144.7 0.0 3.4e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme DUF1517 PF07466.11 EKX52454.1 - 2e-09 37.8 0.7 4e-09 36.9 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) LRR_8 PF13855.6 EKX52455.1 - 0.00016 21.3 0.4 0.007 16.1 0.6 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 EKX52455.1 - 0.0034 17.8 0.7 0.045 14.2 0.7 2.2 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) DUF3682 PF12446.8 EKX52455.1 - 0.033 14.7 7.5 0.052 14.0 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) LRR_1 PF00560.33 EKX52455.1 - 0.086 13.4 0.3 3.3 8.6 0.5 2.5 2 0 0 2 2 2 0 Leucine Rich Repeat Allantoicase PF03561.15 EKX52455.1 - 0.15 12.1 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 Allantoicase repeat Phage_Gp23 PF10669.9 EKX52455.1 - 0.8 10.0 3.8 1.2 9.5 3.8 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Kinesin PF00225.23 EKX52456.1 - 4.2e-92 308.6 0.0 5.2e-92 308.3 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX52456.1 - 2.1e-22 79.6 0.0 4.3e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding PRRSV_2b PF07069.11 EKX52456.1 - 9.8 6.8 8.7 10 6.7 0.7 3.7 2 1 1 3 3 3 0 Porcine reproductive and respiratory syndrome virus 2b Epimerase PF01370.21 EKX52457.1 - 1.3e-52 178.6 0.0 1.9e-52 178.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EKX52457.1 - 9.5e-28 97.5 0.0 2.4e-27 96.2 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EKX52457.1 - 3.3e-12 46.0 0.0 4.8e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EKX52457.1 - 4.8e-09 36.4 0.0 1.9e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EKX52457.1 - 2.6e-08 33.4 0.0 7.6e-05 22.0 0.1 2.5 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EKX52457.1 - 1.6e-06 27.5 0.0 2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EKX52457.1 - 0.00092 18.5 0.0 0.0058 15.8 0.0 2.2 3 0 0 3 3 3 1 Male sterility protein NmrA PF05368.13 EKX52457.1 - 0.0025 17.4 0.0 0.0052 16.4 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family Abhydrolase_1 PF00561.20 EKX52457.1 - 0.077 12.6 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold WD40 PF00400.32 EKX52458.1 - 0.015 16.1 4.0 5.2 8.1 0.1 4.0 3 1 1 4 4 4 0 WD domain, G-beta repeat Ank_5 PF13857.6 EKX52459.1 - 4e-13 49.3 1.4 7.4e-07 29.3 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX52459.1 - 4.3e-12 46.4 0.1 5e-12 46.2 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX52459.1 - 5.8e-12 45.5 0.6 1.3e-07 31.8 0.5 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EKX52459.1 - 3.5e-11 42.3 0.1 1.2e-06 28.4 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EKX52459.1 - 1e-10 41.9 1.1 0.00012 22.5 0.1 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) THB PF18362.1 EKX52459.1 - 0.22 11.2 0.4 0.43 10.2 0.4 1.5 1 0 0 1 1 1 0 Tri-helix bundle domain SnoaL PF07366.12 EKX52460.1 - 0.093 12.5 0.1 0.34 10.7 0.1 1.9 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase SF3b1 PF08920.10 EKX52462.1 - 9.7e-37 126.1 0.7 9.7e-37 126.1 0.7 3.3 2 1 1 3 3 3 1 Splicing factor 3B subunit 1 HEAT PF02985.22 EKX52462.1 - 1.7e-10 40.2 5.7 0.53 10.7 0.1 8.7 9 0 0 9 9 8 2 HEAT repeat HEAT_2 PF13646.6 EKX52462.1 - 3.9e-10 40.0 8.0 0.047 14.1 0.0 8.0 4 2 6 10 10 10 4 HEAT repeats HEAT_EZ PF13513.6 EKX52462.1 - 2.4e-08 34.3 5.1 1.1 9.8 0.0 7.4 7 1 1 8 8 8 3 HEAT-like repeat ParcG PF10274.9 EKX52462.1 - 2.5e-05 24.5 0.5 0.013 15.6 0.0 4.2 2 1 1 3 3 3 1 Parkin co-regulated protein Cnd1 PF12717.7 EKX52462.1 - 4.9e-05 23.4 7.0 2.9 7.9 0.0 6.4 7 1 1 8 8 8 2 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 EKX52462.1 - 5.3e-05 23.1 0.7 1 9.3 0.0 5.5 3 3 1 5 5 5 1 UME (NUC010) domain NUC173 PF08161.12 EKX52462.1 - 7.4e-05 22.5 0.3 0.86 9.2 0.0 3.8 4 0 0 4 4 4 2 NUC173 domain CLASP_N PF12348.8 EKX52462.1 - 0.00074 19.1 0.7 2.9 7.4 0.1 3.4 3 0 0 3 3 3 2 CLASP N terminal Vac14_Fab1_bd PF12755.7 EKX52462.1 - 0.0011 19.6 0.3 1.2 9.8 0.0 4.5 3 1 0 4 4 4 1 Vacuolar 14 Fab1-binding region Apolipoprotein PF01442.18 EKX52462.1 - 0.0061 16.4 2.1 0.62 9.9 0.0 3.3 3 1 0 3 3 3 1 Apolipoprotein A1/A4/E domain Adaptin_N PF01602.20 EKX52462.1 - 0.043 12.4 0.0 1.6 7.2 0.0 2.4 1 1 1 2 2 2 0 Adaptin N terminal region DNA_pol_phi PF04931.13 EKX52462.1 - 0.42 8.7 2.0 7.5 4.5 0.0 2.5 3 0 0 3 3 3 0 DNA polymerase phi LpxK PF02606.14 EKX52463.1 - 1.3e-54 185.5 0.4 1.1e-53 182.4 0.4 1.9 1 1 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase Kinase-PPPase PF03618.14 EKX52463.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinase/pyrophosphorylase Polyketide_cyc2 PF10604.9 EKX52464.1 - 8.5e-06 26.1 0.0 2e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EKX52464.1 - 0.0028 17.8 0.0 0.0078 16.4 0.0 1.7 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport zf-4CXXC_R1 PF10497.9 EKX52465.1 - 0.00061 20.0 21.7 0.0012 19.0 21.7 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 TPR_12 PF13424.6 EKX52466.1 - 7.2e-21 74.3 1.7 7.8e-13 48.5 0.2 4.8 2 1 2 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX52466.1 - 4.1e-17 61.5 0.2 4.2e-08 32.8 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX52466.1 - 1.5e-11 43.6 0.1 0.0081 16.3 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX52466.1 - 2.3e-09 36.7 1.2 0.0091 16.0 0.1 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat RmlD_sub_bind PF04321.17 EKX52466.1 - 6.8e-08 31.9 0.0 7.5e-06 25.2 0.1 2.7 2 1 0 2 2 2 1 RmlD substrate binding domain TPR_1 PF00515.28 EKX52466.1 - 9.9e-08 31.5 0.8 0.0013 18.5 0.0 4.5 6 0 0 6 6 6 2 Tetratricopeptide repeat Epimerase PF01370.21 EKX52466.1 - 1.5e-07 31.2 0.2 1.9e-05 24.2 0.1 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TPR_7 PF13176.6 EKX52466.1 - 5e-07 29.3 0.1 0.1 12.7 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX52466.1 - 2.5e-05 24.7 0.3 16 6.6 0.1 5.7 4 1 2 6 6 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 EKX52466.1 - 6.9e-05 22.5 0.1 0.51 10.1 0.0 3.7 3 0 0 3 3 3 2 TPR repeat SNAP PF14938.6 EKX52466.1 - 0.00023 20.7 0.3 0.015 14.8 0.0 2.4 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP MIT PF04212.18 EKX52466.1 - 0.053 13.6 2.2 0.15 12.2 0.0 2.8 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Ribosomal_S7 PF00177.21 EKX52466.1 - 0.12 12.0 0.2 0.79 9.4 0.1 2.4 2 1 1 3 3 3 0 Ribosomal protein S7p/S5e Pho88 PF10032.9 EKX52467.1 - 5.2e-30 104.1 0.2 5.9e-30 103.9 0.2 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) LPG_synthase_TM PF03706.13 EKX52467.1 - 0.0065 16.0 0.3 0.0082 15.7 0.3 1.0 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region FixO PF02433.15 EKX52467.1 - 0.01 15.3 0.0 0.02 14.4 0.0 1.4 2 0 0 2 2 2 0 Cytochrome C oxidase, mono-heme subunit/FixO PhoD PF09423.10 EKX52468.1 - 5.2e-19 68.5 0.5 1.1e-18 67.5 0.5 1.5 1 1 0 1 1 1 1 PhoD-like phosphatase Metallophos PF00149.28 EKX52468.1 - 0.047 14.2 1.1 0.14 12.7 1.1 1.7 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase AAA_22 PF13401.6 EKX52469.1 - 5.5e-11 42.9 0.0 1.4e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EKX52469.1 - 2.8e-10 40.7 0.0 9.8e-10 39.0 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.11 EKX52469.1 - 1.6e-08 34.4 0.0 4.3e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_16 PF13191.6 EKX52469.1 - 5.8e-08 33.3 0.0 1.1e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 EKX52469.1 - 0.0033 17.0 0.0 0.0067 16.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_30 PF13604.6 EKX52469.1 - 0.0049 16.6 0.0 0.011 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EKX52469.1 - 0.013 15.9 1.0 0.064 13.6 0.3 2.4 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EKX52469.1 - 0.016 14.4 0.1 0.078 12.2 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain T2SSE PF00437.20 EKX52469.1 - 0.019 14.1 0.0 0.035 13.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Pox_A32 PF04665.12 EKX52469.1 - 0.034 13.6 0.0 0.059 12.8 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein DUF815 PF05673.13 EKX52469.1 - 0.1 11.8 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.6 EKX52469.1 - 0.1 12.3 0.1 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_lid_10 PF17872.1 EKX52469.1 - 0.11 12.6 0.1 0.26 11.4 0.1 1.6 1 0 0 1 1 1 0 AAA lid domain AAA_32 PF13654.6 EKX52469.1 - 0.13 11.0 0.0 0.25 10.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EKX52469.1 - 0.17 12.3 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DEAD PF00270.29 EKX52469.1 - 0.62 9.8 2.6 9.9 5.9 0.2 2.6 2 1 1 3 3 3 0 DEAD/DEAH box helicase SpoIIE PF07228.12 EKX52470.1 - 0.089 12.7 0.0 0.48 10.3 0.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) SpoIIE PF07228.12 EKX52471.1 - 0.084 12.8 0.0 0.47 10.3 0.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Kelch_1 PF01344.25 EKX52472.1 - 5.8e-06 25.8 5.0 0.0011 18.5 0.0 4.4 3 1 0 3 3 3 1 Kelch motif Kelch_6 PF13964.6 EKX52472.1 - 6.4e-06 26.3 13.2 0.0079 16.5 0.1 5.7 5 2 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 EKX52472.1 - 0.00034 20.6 7.8 0.1 12.6 0.1 5.3 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.15 EKX52472.1 - 0.0036 17.2 4.9 0.03 14.3 0.0 4.3 5 0 0 5 5 5 1 Kelch motif Kelch_5 PF13854.6 EKX52472.1 - 0.023 14.7 0.2 0.023 14.7 0.2 3.8 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.6 EKX52472.1 - 0.22 11.8 21.5 0.73 10.2 0.2 6.5 8 0 0 8 8 8 0 Galactose oxidase, central domain TRP PF06011.12 EKX52473.1 - 6.9e-08 31.6 4.2 9.2e-08 31.2 4.2 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel FGF-BP1 PF06473.12 EKX52473.1 - 0.0068 16.3 8.6 0.0096 15.8 8.6 1.3 1 0 0 1 1 1 1 FGF binding protein 1 (FGF-BP1) DUF4778 PF16008.5 EKX52473.1 - 0.012 15.7 2.3 0.018 15.1 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) DUF4746 PF15928.5 EKX52473.1 - 0.14 11.6 11.8 0.19 11.1 11.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF2151 PF10221.9 EKX52473.1 - 0.18 10.3 5.2 0.23 10.0 5.2 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator CDC45 PF02724.14 EKX52473.1 - 0.25 9.6 7.6 0.31 9.3 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein eIF3_subunit PF08597.10 EKX52473.1 - 0.31 10.9 22.4 0.42 10.5 22.4 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit RNA_pol_Rpc4 PF05132.14 EKX52473.1 - 0.43 11.0 4.1 0.72 10.3 4.1 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Folliculin PF11704.8 EKX52473.1 - 0.5 10.2 4.6 0.99 9.3 3.9 1.8 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport NARP1 PF12569.8 EKX52473.1 - 1.1 8.0 15.6 1.7 7.5 15.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 MCM_bind PF09739.9 EKX52473.1 - 1.2 7.5 9.5 1.6 7.0 9.5 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Hid1 PF12722.7 EKX52473.1 - 1.3 7.1 8.3 0.68 8.0 6.5 1.4 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Paramyxo_ncap PF00973.19 EKX52473.1 - 2.3 7.1 7.0 3.5 6.4 7.0 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein NPR3 PF03666.13 EKX52473.1 - 2.7 6.7 6.7 3.8 6.2 6.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 RR_TM4-6 PF06459.12 EKX52473.1 - 4.1 7.1 13.5 6.3 6.5 13.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 EKX52473.1 - 4.6 5.9 8.4 7.6 5.2 8.4 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SGT1 PF07093.11 EKX52473.1 - 6.7 5.0 12.5 4.7 5.5 9.6 1.8 2 0 0 2 2 2 0 SGT1 protein PTPRCAP PF15713.5 EKX52473.1 - 7.2 6.9 17.6 12 6.2 17.6 1.3 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Paf1 PF03985.13 EKX52473.1 - 7.6 5.4 18.4 11 4.9 18.4 1.2 1 0 0 1 1 1 0 Paf1 DUF913 PF06025.12 EKX52473.1 - 10 5.0 7.2 16 4.3 7.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) zf-4CXXC_R1 PF10497.9 EKX52474.1 - 0.002 18.3 21.5 0.008 16.4 21.5 2.0 1 1 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Fis1_TPR_C PF14853.6 EKX52474.1 - 0.13 12.3 0.2 0.31 11.1 0.2 1.6 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat FAM76 PF16046.5 EKX52476.1 - 2.2 7.6 10.9 2.5 7.4 10.9 1.0 1 0 0 1 1 1 0 FAM76 protein ALMT PF11744.8 EKX52476.1 - 9.9 4.9 8.4 11 4.7 8.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Reg_prop PF07494.11 EKX52477.1 - 0.0021 18.0 0.0 13 6.4 0.0 4.1 3 1 1 4 4 4 2 Two component regulator propeller Methyltransf_22 PF13383.6 EKX52478.1 - 5.2e-12 45.9 0.2 1.1e-11 44.8 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 EKX52478.1 - 0.0012 18.8 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain PIN_8 PF18476.1 EKX52481.1 - 0.11 12.3 0.6 0.35 10.7 0.1 2.0 2 0 0 2 2 2 0 PIN like domain RNase_PH PF01138.21 EKX52482.1 - 1.3e-05 25.7 0.2 3.2e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EKX52482.1 - 0.0014 18.6 0.1 0.0026 17.8 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Asn_synthase PF00733.21 EKX52483.1 - 2e-14 54.0 0.0 4.6e-14 52.8 0.0 1.4 1 1 1 2 2 2 1 Asparagine synthase QueC PF06508.13 EKX52483.1 - 0.13 11.8 0.0 0.84 9.1 0.0 2.1 1 1 0 1 1 1 0 Queuosine biosynthesis protein QueC Sugar_tr PF00083.24 EKX52484.1 - 7.8e-38 130.5 26.2 1e-37 130.1 26.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EKX52484.1 - 4e-36 124.7 37.0 1e-26 93.7 14.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily IBR PF01485.21 EKX52485.1 - 1.7e-07 31.4 11.8 1.7e-07 31.4 11.8 4.2 2 1 1 3 3 3 1 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EKX52485.1 - 0.01 16.2 4.3 0.01 16.2 4.3 3.8 3 0 0 3 3 3 0 Ring finger domain zf-C3HC4_2 PF13923.6 EKX52485.1 - 0.42 10.5 21.7 0.19 11.6 2.0 3.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX52485.1 - 1 9.3 23.3 0.085 12.7 1.9 3.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.25 EKX52486.1 - 9.8e-17 61.2 0.0 3.7e-15 56.0 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX52486.1 - 1.6e-12 47.3 0.0 5.6e-11 42.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX52486.1 - 3.4e-05 23.9 0.0 9.9e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EKX52486.1 - 0.0028 17.3 0.0 0.0052 16.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EKX52486.1 - 0.027 14.1 0.0 0.23 11.0 0.0 2.4 3 0 0 3 3 3 0 Choline/ethanolamine kinase DUF2196 PF09962.9 EKX52486.1 - 0.11 12.6 0.2 0.24 11.4 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2196) DALR_1 PF05746.15 EKX52486.1 - 0.15 12.3 0.1 0.61 10.3 0.0 2.0 2 0 0 2 2 2 0 DALR anticodon binding domain OppC_N PF12911.7 EKX52487.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C YrhK PF14145.6 EKX52487.1 - 0.14 12.0 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 YrhK-like protein Ax_dynein_light PF10211.9 EKX52488.1 - 1.7e-81 272.7 10.2 1.9e-81 272.5 10.2 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain COQ7 PF03232.13 EKX52488.1 - 0.0035 17.1 0.6 0.0057 16.4 0.6 1.3 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 PCRF PF03462.18 EKX52488.1 - 0.013 15.4 7.5 0.021 14.7 7.5 1.3 1 0 0 1 1 1 0 PCRF domain YlbD_coat PF14071.6 EKX52488.1 - 0.017 15.3 1.2 0.033 14.4 1.2 1.4 1 0 0 1 1 1 0 Putative coat protein Collectrin PF16959.5 EKX52488.1 - 0.048 13.4 0.3 0.078 12.7 0.3 1.3 1 0 0 1 1 1 0 Renal amino acid transporter Speriolin_N PF15058.6 EKX52488.1 - 0.06 13.4 2.5 0.12 12.5 2.5 1.5 1 0 0 1 1 1 0 Speriolin N terminus DUF3648 PF12364.8 EKX52488.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3648) bZIP_1 PF00170.21 EKX52488.1 - 0.21 11.7 11.7 0.61 10.2 4.3 2.5 1 1 1 2 2 2 0 bZIP transcription factor UPF0242 PF06785.11 EKX52488.1 - 0.3 11.2 8.6 0.13 12.3 6.1 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Syntaxin-6_N PF09177.11 EKX52488.1 - 0.82 10.3 7.1 0.29 11.7 4.0 1.9 2 1 0 2 2 2 0 Syntaxin 6, N-terminal bZIP_2 PF07716.15 EKX52488.1 - 1 9.5 17.6 3.6 7.8 6.3 2.6 2 0 0 2 2 2 0 Basic region leucine zipper PIN_12 PF16289.5 EKX52488.1 - 1.9 8.9 5.8 1.5 9.3 4.4 1.5 2 0 0 2 2 2 0 PIN domain NYD-SP28_assoc PF14775.6 EKX52488.1 - 9.6 6.4 8.4 18 5.5 0.8 3.0 2 1 0 2 2 2 0 Sperm tail C-terminal domain adh_short_C2 PF13561.6 EKX52490.1 - 2.8e-58 197.3 0.2 3.1e-58 197.1 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EKX52490.1 - 2.6e-49 167.3 1.1 5.2e-49 166.4 1.2 1.4 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.10 EKX52490.1 - 3e-07 30.5 0.3 4.3e-07 30.0 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EKX52490.1 - 0.013 15.0 0.4 0.04 13.4 0.4 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 4HFCP_synth PF04476.13 EKX52490.1 - 0.086 12.5 0.0 0.23 11.2 0.0 1.6 1 1 1 2 2 2 0 4-HFC-P synthase LysM PF01476.20 EKX52491.1 - 0.00076 19.5 0.2 0.0093 16.0 0.2 3.0 2 0 0 2 2 2 1 LysM domain Ank_2 PF12796.7 EKX52492.1 - 1.1e-21 77.2 1.1 1.1e-14 54.8 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX52492.1 - 2e-18 66.5 0.0 1.7e-11 44.4 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX52492.1 - 3.5e-18 65.2 0.2 0.0003 21.1 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EKX52492.1 - 9.2e-17 60.9 0.1 1e-08 35.2 0.0 3.7 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX52492.1 - 2.1e-10 39.9 0.1 0.012 16.0 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ephrin_rec_like PF07699.13 EKX52493.1 - 3.7e-35 119.4 73.7 1.4e-10 40.7 8.6 8.3 3 2 6 9 9 9 9 Putative ephrin-receptor like NCD3G PF07562.14 EKX52493.1 - 1.3e-16 60.3 46.0 0.00021 21.2 1.2 7.4 4 2 3 7 7 7 7 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX52493.1 - 1.1e-10 41.7 49.1 0.074 13.5 0.0 10.4 3 3 8 11 11 11 10 TNFR/NGFR cysteine-rich region WD40 PF00400.32 EKX52494.1 - 0.0045 17.8 2.4 2.4 9.2 0.1 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat p450 PF00067.22 EKX52495.1 - 1.4e-49 169.1 0.0 2.1e-49 168.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 IF4E PF01652.18 EKX52499.1 - 4.7e-52 176.0 0.1 5.7e-52 175.7 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E ABC2_membrane PF01061.24 EKX52501.1 - 5.5e-43 146.8 15.5 8.8e-43 146.2 15.5 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EKX52501.1 - 1.2e-25 90.6 0.1 2.4e-25 89.7 0.1 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EKX52501.1 - 3.3e-07 29.8 14.8 4.6e-07 29.3 14.8 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 EKX52501.1 - 0.00014 21.7 0.1 0.057 13.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EKX52501.1 - 0.00085 19.3 0.1 0.0015 18.5 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 EKX52501.1 - 0.00096 18.8 0.1 0.0021 17.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EKX52501.1 - 0.0068 16.9 1.0 0.012 16.1 1.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EKX52501.1 - 0.007 16.1 0.8 0.016 15.0 0.8 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EKX52501.1 - 0.029 13.8 0.1 0.44 10.0 0.1 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EKX52501.1 - 0.05 13.7 0.2 0.14 12.2 0.2 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 EKX52501.1 - 0.053 13.8 0.0 0.096 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EKX52501.1 - 0.06 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 EKX52501.1 - 0.081 12.6 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EKX52501.1 - 0.092 12.3 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 EKX52501.1 - 0.13 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EKX52501.1 - 0.17 12.2 0.0 0.41 10.9 0.0 1.6 2 0 0 2 2 1 0 AAA domain Na_Ca_ex PF01699.24 EKX52502.1 - 5.9e-18 65.3 17.7 1.5e-11 44.5 7.7 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein EF-hand_7 PF13499.6 EKX52502.1 - 1.9e-14 53.9 1.4 3.8e-14 52.9 1.4 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX52502.1 - 3.4e-14 51.2 2.7 3.1e-06 26.3 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX52502.1 - 4.4e-12 44.9 2.0 7.2e-06 25.5 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 EKX52502.1 - 2.8e-11 42.4 1.2 3.9e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX52502.1 - 1.8e-07 30.9 3.6 0.0025 17.6 1.4 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 EKX52502.1 - 0.015 15.6 0.1 0.029 14.7 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain UQ_con PF00179.26 EKX52503.1 - 1.5e-36 125.1 0.0 1.9e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EKX52503.1 - 0.00059 19.5 0.0 0.0008 19.1 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B Glyco_transf_11 PF01531.16 EKX52504.1 - 0.00056 19.2 0.0 0.00073 18.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 11 Inositol_P PF00459.25 EKX52506.1 - 3.6e-58 197.2 0.0 4.3e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family FBPase_glpX PF03320.13 EKX52506.1 - 0.013 14.4 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded Ax_dynein_light PF10211.9 EKX52508.1 - 6.3e-92 306.7 13.8 7.2e-92 306.5 13.8 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain Syntaxin-6_N PF09177.11 EKX52508.1 - 0.0026 18.3 7.2 0.0026 18.3 7.2 1.8 2 0 0 2 2 2 1 Syntaxin 6, N-terminal Tropomyosin_1 PF12718.7 EKX52508.1 - 0.025 14.7 12.3 0.025 14.7 12.3 1.5 2 0 0 2 2 1 0 Tropomyosin like bZIP_2 PF07716.15 EKX52508.1 - 0.026 14.6 22.7 0.04 14.0 6.6 3.1 2 1 1 3 3 3 0 Basic region leucine zipper DUF5320 PF17253.2 EKX52508.1 - 0.032 15.3 9.2 0.21 12.7 1.6 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5320) FapA PF03961.13 EKX52508.1 - 0.057 12.0 5.7 0.085 11.5 5.7 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Jnk-SapK_ap_N PF09744.9 EKX52508.1 - 0.067 13.4 16.3 0.089 13.0 11.4 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 UPF0242 PF06785.11 EKX52508.1 - 0.07 13.2 12.4 0.025 14.7 9.1 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus End3 PF12761.7 EKX52508.1 - 0.071 13.3 9.5 0.034 14.3 7.4 1.6 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 PilJ PF13675.6 EKX52508.1 - 0.12 12.5 4.1 0.28 11.2 4.1 1.7 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term LRRFIP PF09738.9 EKX52508.1 - 0.12 11.9 17.2 0.24 10.8 8.7 2.1 1 1 1 2 2 2 0 LRRFIP family ADIP PF11559.8 EKX52508.1 - 0.21 11.7 14.4 0.5 10.4 14.4 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding EMP24_GP25L PF01105.24 EKX52508.1 - 0.26 11.2 7.5 0.1 12.5 3.2 2.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD FlaC_arch PF05377.11 EKX52508.1 - 0.39 11.1 7.7 2.8 8.4 2.4 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) GP41 PF00517.17 EKX52508.1 - 0.49 10.3 3.7 11 5.9 0.1 2.4 2 1 0 2 2 2 0 Retroviral envelope protein APG6_N PF17675.1 EKX52508.1 - 0.71 10.4 22.7 3.7 8.1 22.6 2.2 1 1 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 EKX52508.1 - 2.7 7.8 18.2 0.035 13.9 5.2 2.9 2 1 1 3 3 3 0 Septum formation initiator AbiH PF14253.6 EKX52508.1 - 3 7.6 5.0 3.4 7.5 5.0 1.3 1 1 0 1 1 1 0 Bacteriophage abortive infection AbiH GrpE PF01025.19 EKX52508.1 - 3 7.5 12.7 3.4 7.3 10.4 2.2 2 2 0 2 2 2 0 GrpE Spc24 PF08286.11 EKX52508.1 - 4.2 7.7 14.1 0.61 10.4 5.7 2.6 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 PRKG1_interact PF15898.5 EKX52508.1 - 5.5 8.0 16.5 4.3 8.3 13.7 2.2 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Guanylate_cyc PF00211.20 EKX52509.1 - 2.9e-24 85.7 0.2 3.2e-24 85.6 0.2 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 EKX52510.1 - 3.7e-23 82.1 0.0 4.3e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Synaptobrevin PF00957.21 EKX52511.1 - 0.0021 17.8 0.8 0.0039 17.0 0.8 1.4 1 0 0 1 1 1 1 Synaptobrevin DUF4592 PF15262.6 EKX52511.1 - 8.8 7.0 14.2 0.66 10.7 5.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4592) KxDL PF10241.9 EKX52512.1 - 0.073 13.4 6.6 0.13 12.6 1.2 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein CAP_N PF01213.19 EKX52512.1 - 0.23 10.9 6.6 0.32 10.4 6.6 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Baculo_p24 PF05073.12 EKX52512.1 - 0.32 10.7 3.9 0.62 9.8 3.9 1.5 1 0 0 1 1 1 0 Baculovirus P24 capsid protein Baculo_PEP_C PF04513.12 EKX52512.1 - 0.36 10.9 4.5 0.3 11.1 2.0 2.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.12 EKX52512.1 - 0.63 10.0 10.0 0.15 12.1 6.0 1.9 2 0 0 2 2 2 0 Laminin Domain II Nup88 PF10168.9 EKX52512.1 - 0.74 7.5 20.2 0.95 7.2 20.2 1.1 1 0 0 1 1 1 0 Nuclear pore component DUF1664 PF07889.12 EKX52512.1 - 0.86 9.7 12.4 1.9 8.5 0.6 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) FapA PF03961.13 EKX52512.1 - 2.6 6.5 22.6 0.016 13.8 11.0 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A BLOC1_2 PF10046.9 EKX52512.1 - 2.8 8.3 14.9 3.9 7.8 9.0 3.2 2 2 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 COG2 PF06148.11 EKX52512.1 - 2.8 8.0 18.5 1.1 9.4 7.5 2.9 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DASH_Spc19 PF08287.11 EKX52512.1 - 7.6 6.4 32.5 0.26 11.2 11.0 2.6 1 1 1 2 2 2 0 Spc19 YtxH PF12732.7 EKX52512.1 - 8.7 7.0 7.5 6.1 7.4 4.2 2.4 2 1 0 2 2 2 0 YtxH-like protein SKIP_SNW PF02731.15 EKX52513.1 - 4.4e-64 215.0 1.6 4.4e-64 215.0 1.6 2.5 2 0 0 2 2 2 1 SKIP/SNW domain GRP PF07172.11 EKX52513.1 - 0.0097 16.6 10.2 0.033 14.9 10.2 1.9 1 0 0 1 1 1 1 Glycine rich protein family SNAP PF14938.6 EKX52514.1 - 2.7e-09 36.9 5.6 6.8e-07 29.0 0.9 2.1 1 1 1 2 2 2 2 Soluble NSF attachment protein, SNAP ELMO_CED12 PF04727.13 EKX52515.1 - 1.5e-36 126.2 0.0 2e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 ELMO/CED-12 family MA3 PF02847.17 EKX52518.1 - 8.1e-22 77.3 0.0 2.5e-21 75.8 0.0 1.9 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 EKX52518.1 - 4.6e-20 72.2 0.0 4.6e-20 72.2 0.0 2.6 2 0 0 2 2 2 1 MIF4G domain TFIIA PF03153.13 EKX52518.1 - 0.017 15.1 32.9 0.029 14.4 32.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macro PF01661.21 EKX52518.1 - 0.045 13.8 0.1 0.16 12.0 0.1 1.9 1 0 0 1 1 1 0 Macro domain Kinesin_assoc PF16183.5 EKX52518.1 - 3.2 7.9 10.2 12 6.0 10.2 2.1 1 1 0 1 1 1 0 Kinesin-associated PK PF00224.21 EKX52520.1 - 3e-138 460.5 7.7 1.9e-137 457.8 7.7 2.0 1 1 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EKX52520.1 - 7.3e-29 100.4 1.0 2.3e-28 98.7 0.5 2.2 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EKX52520.1 - 0.0053 15.9 0.0 0.011 14.9 0.0 1.6 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PDZ PF00595.24 EKX52521.1 - 7e-10 39.1 0.1 3.2e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EKX52521.1 - 3.1e-07 30.1 0.3 8.9e-07 28.7 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX52521.1 - 2.4e-06 27.8 0.0 6.4e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Clathrin_lg_ch PF01086.17 EKX52521.1 - 0.016 15.3 0.5 0.016 15.3 0.5 1.9 2 0 0 2 2 2 0 Clathrin light chain BPL_LplA_LipB PF03099.19 EKX52523.1 - 0.0024 17.8 0.1 0.014 15.3 0.1 2.0 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.9 EKX52524.1 - 6.8e-09 35.6 0.0 4.4e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 Bacterial lipoate protein ligase C-terminus DEC-1_N PF04625.13 EKX52524.1 - 0.00083 18.5 9.9 0.00093 18.3 9.9 1.2 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region DUF5525 PF17663.1 EKX52524.1 - 0.00097 17.4 7.4 0.001 17.3 7.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5525) Ribosomal_60s PF00428.19 EKX52524.1 - 1.3 9.6 6.7 4.3 8.0 5.4 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Peptidase_S8 PF00082.22 EKX52525.1 - 2.4e-14 53.3 0.0 4.6e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Subtilase family EGF_Tenascin PF18720.1 EKX52525.1 - 0.014 15.4 13.7 0.067 13.3 13.7 2.2 1 0 0 1 1 1 0 Tenascin EGF domain Peptidase_M48_N PF16491.5 EKX52526.1 - 5.4e-58 195.9 9.3 1.3e-57 194.7 9.3 1.7 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EKX52526.1 - 5e-38 130.8 0.0 3.1e-36 125.0 0.0 2.9 2 1 0 2 2 2 1 Peptidase family M48 Peptidase_M56 PF05569.11 EKX52526.1 - 2.9 7.0 6.9 22 4.1 1.7 3.1 3 0 0 3 3 3 0 BlaR1 peptidase M56 Ion_trans PF00520.31 EKX52527.1 - 1.9e-21 76.4 15.0 1.7e-16 60.2 2.0 2.3 1 1 1 2 2 2 2 Ion transport protein PH PF00169.29 EKX52527.1 - 2.8e-07 31.0 0.3 2e-06 28.2 0.3 2.2 1 1 0 1 1 1 1 PH domain PKD_channel PF08016.12 EKX52527.1 - 4.1e-05 22.4 8.1 0.0002 20.2 8.1 1.9 1 1 0 1 1 1 1 Polycystin cation channel Myosin_TH1 PF06017.13 EKX52527.1 - 0.0016 18.2 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding Cadherin_3 PF16184.5 EKX52527.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Cadherin-like PA PF02225.22 EKX52529.1 - 0.0063 16.5 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M55 PF04951.13 EKX52529.1 - 0.0075 15.7 0.3 0.016 14.6 0.1 1.5 1 1 0 1 1 1 1 D-aminopeptidase IFRD_C PF04836.12 EKX52529.1 - 0.026 15.1 0.8 0.026 15.1 0.8 2.0 2 0 0 2 2 2 0 Interferon-related protein conserved region FliD_C PF07195.12 EKX52529.1 - 1.6 8.1 7.1 28 4.0 6.5 2.1 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Thioredoxin PF00085.20 EKX52530.1 - 2.6e-15 56.3 0.0 5.5e-14 52.0 0.0 2.9 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 EKX52530.1 - 6.2e-15 55.6 0.0 9.7e-12 45.2 0.0 3.1 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EKX52530.1 - 0.075 13.4 0.0 30 5.0 0.0 3.4 4 0 0 4 4 4 0 Thioredoxin-like KfrA_N PF11740.8 EKX52531.1 - 0.0055 17.4 1.5 0.0055 17.4 1.5 2.8 1 1 1 2 2 2 1 Plasmid replication region DNA-binding N-term Mit_KHE1 PF10173.9 EKX52531.1 - 0.77 9.8 3.1 1 9.4 3.1 1.3 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related V_ATPase_I PF01496.19 EKX52531.1 - 2.3 6.0 6.3 2.6 5.8 6.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OmpH PF03938.14 EKX52531.1 - 3.7 7.9 13.8 0.88 9.9 7.9 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF3552 PF12072.8 EKX52531.1 - 4.3 6.7 27.5 0.02 14.3 15.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Halo_GVPC PF05465.13 EKX52532.1 - 0.028 14.7 0.4 7.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat PALP PF00291.25 EKX52532.1 - 0.16 11.3 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Gram_pos_anchor PF00746.21 EKX52532.1 - 0.49 10.4 0.1 0.49 10.4 0.1 2.2 2 0 0 2 2 2 0 LPXTG cell wall anchor motif 2OG-FeII_Oxy_5 PF13759.6 EKX52534.1 - 0.068 13.6 0.1 0.068 13.6 0.1 1.2 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase PC4 PF02229.16 EKX52535.1 - 4.5e-14 51.8 0.1 8.7e-14 50.9 0.1 1.5 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Podoplanin PF05808.11 EKX52535.1 - 0.097 12.8 2.9 0.15 12.2 2.9 1.3 1 0 0 1 1 1 0 Podoplanin TTL PF03133.15 EKX52536.1 - 1.4e-14 54.0 0.0 1.1e-13 51.0 0.0 2.0 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EKX52536.1 - 8.4e-07 28.5 0.0 1.1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EKX52536.1 - 0.0072 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp TPR_1 PF00515.28 EKX52537.1 - 2.5e-22 77.7 24.5 0.00018 21.1 0.1 14.3 16 0 0 16 16 16 4 Tetratricopeptide repeat TPR_11 PF13414.6 EKX52537.1 - 1.3e-18 66.3 7.3 6.2e-06 25.8 0.0 9.5 10 1 1 11 11 11 4 TPR repeat TPR_12 PF13424.6 EKX52537.1 - 1.7e-18 66.7 3.7 9.4e-05 22.6 0.0 8.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX52537.1 - 1.4e-17 62.3 27.1 0.015 15.4 0.0 14.5 17 0 0 17 17 16 4 Tetratricopeptide repeat TPR_19 PF14559.6 EKX52537.1 - 3.8e-14 52.9 14.3 0.043 14.3 0.0 11.5 11 1 1 12 12 12 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX52537.1 - 1e-12 48.5 0.0 0.0016 19.0 0.0 7.6 7 1 0 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX52537.1 - 2.8e-10 40.2 0.3 1 9.5 0.0 7.6 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX52537.1 - 3.7e-10 39.2 22.4 2.4 8.6 0.1 12.1 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_17 PF13431.6 EKX52537.1 - 4.7e-10 39.1 0.2 1.4 9.4 0.0 7.7 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX52537.1 - 4.5e-09 36.4 7.2 1 10.3 0.0 10.0 9 2 3 12 12 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX52537.1 - 5.8e-07 29.1 13.5 0.95 9.6 0.1 10.2 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_20 PF14561.6 EKX52537.1 - 0.00013 22.2 0.4 5.4 7.4 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX52537.1 - 0.00025 21.2 0.2 0.86 9.9 0.2 5.4 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EKX52537.1 - 0.003 17.4 6.8 0.095 12.6 0.1 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 EKX52537.1 - 0.013 14.9 4.0 8.8 5.9 0.1 4.8 5 0 0 5 5 5 0 SHNi-TPR TPR_4 PF07721.14 EKX52537.1 - 4.9 8.1 6.0 52 4.9 0.0 5.6 7 0 0 7 7 5 0 Tetratricopeptide repeat RCC1 PF00415.18 EKX52538.1 - 1.3e-67 224.3 12.7 9.5e-15 55.0 0.0 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX52538.1 - 8.1e-37 124.3 31.5 1.4e-09 37.5 0.3 6.7 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Beta_helix PF13229.6 EKX52540.1 - 3.8e-05 23.6 4.2 0.074 12.9 1.0 2.0 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 EKX52540.1 - 0.00054 19.3 1.3 0.00075 18.8 1.3 1.2 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Laminin_G_3 PF13385.6 EKX52541.1 - 3.1e-09 37.1 0.7 2.4e-07 31.0 0.4 2.3 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily PDZ PF00595.24 EKX52542.1 - 3.4e-11 43.3 0.7 0.0002 21.6 0.0 2.7 3 0 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 EKX52542.1 - 3e-10 40.3 0.4 0.0002 21.6 0.1 2.7 3 0 0 3 3 3 2 PDZ domain PDZ_6 PF17820.1 EKX52542.1 - 2.5e-09 36.8 0.0 0.0013 18.5 0.0 2.5 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 EKX52542.1 - 2.3e-05 24.3 0.6 0.25 11.4 0.0 2.8 3 0 0 3 3 3 2 Tricorn protease PDZ domain PDZ_4 PF17816.1 EKX52542.1 - 0.095 13.1 0.0 7.9 6.9 0.0 2.4 2 0 0 2 2 2 0 PDZ domain DPCD PF14913.6 EKX52543.1 - 1e-69 233.8 0.3 1.2e-69 233.5 0.3 1.0 1 0 0 1 1 1 1 DPCD protein family WD40 PF00400.32 EKX52544.1 - 0.03 15.2 0.0 0.072 14.0 0.0 1.7 1 0 0 1 1 1 0 WD domain, G-beta repeat VIT1 PF01988.19 EKX52545.1 - 3 7.6 8.8 0.68 9.8 5.0 1.7 2 0 0 2 2 2 0 VIT family Abhydrolase_1 PF00561.20 EKX52547.1 - 4.8e-18 65.7 0.2 8.7e-18 64.9 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EKX52547.1 - 3.8e-14 52.5 0.8 2.5e-13 49.9 0.2 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EKX52547.1 - 1.9e-12 48.3 3.4 2.7e-12 47.8 3.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 EKX52547.1 - 0.00011 21.7 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.13 EKX52547.1 - 0.00048 19.9 0.1 0.00081 19.2 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF900 PF05990.12 EKX52547.1 - 0.0098 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Lipase_2 PF01674.18 EKX52547.1 - 0.023 14.2 0.0 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 Lipase (class 2) Palm_thioest PF02089.15 EKX52547.1 - 0.15 11.8 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase C2 PF00168.30 EKX52548.1 - 1.6e-14 54.0 0.0 3.2e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain PDZ_2 PF13180.6 EKX52548.1 - 1.5e-08 34.9 0.0 2.6e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX52548.1 - 3.6e-08 33.1 0.1 7.4e-08 32.1 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX52548.1 - 5.6e-06 26.6 0.6 1.2e-05 25.6 0.6 1.5 1 0 0 1 1 1 1 PDZ domain Muted PF14942.6 EKX52550.1 - 0.011 16.1 6.0 0.13 12.6 2.6 2.9 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein Tube PF17212.3 EKX52550.1 - 0.019 15.0 0.5 0.032 14.3 0.5 1.4 1 0 0 1 1 1 0 Tail tubular protein SOAR PF16533.5 EKX52550.1 - 0.13 12.2 4.5 0.19 11.7 1.2 2.6 2 1 1 3 3 3 0 STIM1 Orai1-activating region Noelin-1 PF12308.8 EKX52550.1 - 0.2 11.7 5.3 0.31 11.1 3.6 2.3 1 1 1 2 2 2 0 Neurogenesis glycoprotein LSPR PF06049.12 EKX52550.1 - 0.57 10.2 2.8 1.4 9.1 0.3 2.6 2 0 0 2 2 2 0 Coagulation Factor V LSPD Repeat Cep57_CLD_2 PF14197.6 EKX52550.1 - 1.2 9.3 5.8 0.51 10.5 1.0 2.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Baculo_PEP_C PF04513.12 EKX52550.1 - 2.2 8.3 9.2 6.6 6.8 6.7 2.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CLZ PF16526.5 EKX52550.1 - 8.2 6.9 11.3 0.82 10.1 0.5 3.3 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels LON_substr_bdg PF02190.16 EKX52551.1 - 5.3e-24 85.3 0.0 6.8e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Sigma70_ner PF04546.13 EKX52551.1 - 0.0075 16.2 0.3 0.01 15.8 0.3 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region DUF3391 PF11871.8 EKX52551.1 - 0.072 13.6 0.6 0.13 12.8 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Abi_C PF14355.6 EKX52551.1 - 0.095 12.8 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Abortive infection C-terminus C2 PF00168.30 EKX52552.1 - 2.4e-20 72.7 0.0 5.4e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.25 EKX52553.1 - 1.6e-49 168.6 0.0 1.9e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX52553.1 - 1.7e-31 109.4 0.0 2.5e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX52553.1 - 0.00025 20.0 0.0 0.00052 18.9 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EKX52553.1 - 0.00067 19.1 0.0 0.012 14.9 0.0 2.3 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 EKX52553.1 - 0.042 13.8 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EKX52553.1 - 0.063 12.3 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 TPR_1 PF00515.28 EKX52554.1 - 2.1e-17 62.1 8.1 8.9e-07 28.5 0.1 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX52554.1 - 6.6e-17 60.2 7.5 1.1e-05 25.2 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX52554.1 - 3.4e-13 48.7 5.4 0.00063 19.8 0.0 6.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX52554.1 - 4.4e-12 46.3 5.6 4.5e-06 27.1 0.0 4.2 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX52554.1 - 5.5e-12 44.8 3.4 0.00022 21.0 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX52554.1 - 1.1e-10 42.0 5.1 1.2e-05 25.8 0.2 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX52554.1 - 4.9e-10 38.9 4.8 9.8e-06 25.2 0.0 4.1 3 1 1 4 4 4 2 TPR repeat TPR_12 PF13424.6 EKX52554.1 - 1.3e-09 38.2 8.6 1.9e-05 24.9 0.2 3.6 4 1 0 4 4 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX52554.1 - 1.5e-09 37.6 5.8 0.0018 18.5 0.0 5.1 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX52554.1 - 1.5e-07 31.1 9.7 0.02 14.7 0.2 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX52554.1 - 2e-05 25.0 8.7 0.89 10.5 0.0 6.0 6 1 1 7 7 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 EKX52554.1 - 0.00027 21.3 5.2 12 6.9 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX52554.1 - 0.0013 19.3 4.4 1.8 9.4 0.0 4.8 5 0 0 5 5 3 1 Tetratricopeptide repeat RPN7 PF10602.9 EKX52554.1 - 0.0013 18.4 0.6 0.33 10.7 0.0 3.4 2 1 1 3 3 3 1 26S proteasome subunit RPN7 TPR_9 PF13371.6 EKX52554.1 - 0.0044 17.1 1.0 9.9 6.4 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 EKX52554.1 - 0.042 14.2 0.3 1.7 9.1 0.0 3.4 1 1 2 4 4 4 0 Tetratricopeptide repeat SNAP PF14938.6 EKX52554.1 - 0.046 13.1 2.2 0.11 11.9 1.7 1.9 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP GARS_A PF01071.19 EKX52555.1 - 8.3e-79 263.9 0.5 1.3e-78 263.3 0.5 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 EKX52555.1 - 4.6e-34 117.1 0.0 1.4e-33 115.5 0.0 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 EKX52555.1 - 1.1e-26 92.9 0.4 2.4e-26 91.8 0.4 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain CPSase_L_D2 PF02786.17 EKX52555.1 - 2.9e-07 30.2 0.1 5.4e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 EKX52555.1 - 1.6e-05 24.6 0.0 2.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.10 EKX52555.1 - 1.8e-05 24.4 0.1 3.4e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EKX52555.1 - 2.9e-05 24.2 0.1 5.3e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 EKX52555.1 - 6.8e-05 22.5 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 EKX52555.1 - 0.0012 18.5 0.1 0.0021 17.7 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EKX52555.1 - 0.0026 17.3 0.1 0.0061 16.1 0.1 1.6 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_5 PF13549.6 EKX52555.1 - 0.0038 16.7 0.1 0.015 14.7 0.1 2.0 2 1 0 2 2 2 1 ATP-grasp domain PucR PF07905.11 EKX52555.1 - 0.13 12.6 0.0 0.8 10.0 0.0 2.4 2 1 0 2 2 2 0 Purine catabolism regulatory protein-like family SesA PF17107.5 EKX52557.1 - 0.57 10.4 3.5 0.58 10.4 1.8 1.8 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases cNMP_binding PF00027.29 EKX52558.1 - 2.5e-14 53.1 0.0 5.5e-14 52.0 0.0 1.6 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain Exo_endo_phos PF03372.23 EKX52559.1 - 2.5e-16 59.9 0.0 3.7e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2634 PF10934.8 EKX52560.1 - 0.16 12.1 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2634) Herpes_DNAp_acc PF04929.12 EKX52561.1 - 1 8.3 5.9 1.5 7.7 5.9 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Hamartin PF04388.12 EKX52561.1 - 1.4 7.5 6.9 1.8 7.1 6.9 1.1 1 0 0 1 1 1 0 Hamartin protein Abhydrolase_1 PF00561.20 EKX52562.1 - 8.8e-23 81.2 0.0 2.8e-21 76.3 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EKX52562.1 - 5.5e-22 79.4 0.0 7.1e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EKX52562.1 - 2.4e-15 56.5 0.0 4.2e-14 52.4 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 EKX52562.1 - 0.00039 20.1 0.0 0.00069 19.3 0.0 1.5 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 EKX52562.1 - 0.00073 19.4 0.0 0.69 9.7 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DLH PF01738.18 EKX52562.1 - 0.0093 15.5 0.0 0.045 13.3 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family LSM PF01423.22 EKX52564.1 - 2e-17 62.6 0.2 2.6e-17 62.3 0.2 1.1 1 0 0 1 1 1 1 LSM domain WW PF00397.26 EKX52566.1 - 1.8e-15 56.7 2.2 4.1e-08 33.2 1.6 2.6 2 0 0 2 2 2 2 WW domain TFIIA PF03153.13 EKX52566.1 - 0.99 9.3 17.7 1.1 9.2 17.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 EKX52566.1 - 3.4 5.8 12.7 4.3 5.5 12.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Esterase PF00756.20 EKX52567.1 - 7.5e-19 68.3 0.0 1.1e-18 67.8 0.0 1.4 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 EKX52567.1 - 4.5e-06 26.1 0.0 6.6e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EKX52567.1 - 0.031 13.8 0.0 0.054 13.0 0.0 1.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EKX52567.1 - 0.074 12.7 0.0 0.34 10.5 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold PDZ PF00595.24 EKX52568.1 - 7.7e-05 23.0 0.0 0.0002 21.6 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX52568.1 - 0.0004 20.2 0.2 0.0017 18.2 0.2 2.1 1 1 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX52568.1 - 0.01 16.1 0.0 0.03 14.6 0.0 1.9 1 1 0 1 1 1 0 PDZ domain DUF3496 PF12001.8 EKX52568.1 - 0.027 14.8 0.2 0.027 14.8 0.2 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF3496) GIT_CC PF16559.5 EKX52568.1 - 0.49 10.3 9.6 0.47 10.4 1.2 2.9 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor CLZ PF16526.5 EKX52568.1 - 1.2 9.5 11.5 0.31 11.4 0.7 3.3 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels YabA PF06156.13 EKX52568.1 - 1.5 9.5 14.7 2.6 8.7 5.7 3.5 2 1 1 3 3 3 0 Initiation control protein YabA Occludin_ELL PF07303.13 EKX52568.1 - 6.4 7.6 9.3 1.5 9.6 1.8 2.9 1 1 2 3 3 3 0 Occludin homology domain His_Phos_1 PF00300.22 EKX52569.1 - 2.9e-20 72.8 0.2 3.6e-18 66.0 0.2 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RRM_3 PF08777.11 EKX52569.1 - 0.025 14.6 0.0 0.058 13.4 0.0 1.7 1 0 0 1 1 1 0 RNA binding motif EF-hand_6 PF13405.6 EKX52570.1 - 2.5e-16 58.1 0.7 2.9e-05 23.6 0.0 6.8 7 0 0 7 7 7 3 EF-hand domain EF-hand_7 PF13499.6 EKX52570.1 - 5.1e-14 52.5 0.7 0.0001 22.6 0.1 4.6 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EKX52570.1 - 6.6e-11 41.0 8.5 9.2e-05 21.7 0.0 7.1 7 0 0 7 7 7 3 EF hand p25-alpha PF05517.12 EKX52570.1 - 1.2e-05 25.6 0.7 0.55 10.4 0.1 3.8 3 0 0 3 3 3 2 p25-alpha EF-hand_8 PF13833.6 EKX52570.1 - 6.1e-05 22.8 5.5 0.65 9.9 0.1 5.8 6 0 0 6 6 6 2 EF-hand domain pair EF-hand_9 PF14658.6 EKX52570.1 - 0.0016 18.7 0.0 0.33 11.3 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 EKX52570.1 - 0.0072 15.8 7.7 0.09 12.3 0.0 5.2 5 0 0 5 5 5 1 EF hand FapA PF03961.13 EKX52570.1 - 0.11 11.0 2.4 0.28 9.7 2.4 1.6 1 0 0 1 1 1 0 Flagellar Assembly Protein A Cnn_1N PF07989.11 EKX52570.1 - 0.18 12.0 7.8 1.3 9.2 0.3 3.6 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Csm1_N PF18504.1 EKX52570.1 - 0.76 10.2 8.8 0.062 13.6 0.8 3.1 3 0 0 3 3 3 0 Csm1 N-terminal domain Peptidase_S9_N PF02897.15 EKX52571.1 - 2e-113 379.3 4.5 2.5e-113 379.0 4.5 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 EKX52571.1 - 1.4e-60 204.4 0.0 2.9e-60 203.4 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Collagen PF01391.18 EKX52572.1 - 4.7e-16 58.3 51.3 6.9e-09 35.3 20.1 2.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) MetW PF07021.12 EKX52573.1 - 0.1 12.2 0.2 0.15 11.6 0.2 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Armet PF10208.9 EKX52573.1 - 0.12 12.3 0.2 0.12 12.3 0.2 1.9 2 1 0 2 2 2 0 Degradation arginine-rich protein for mis-folding Alpha_kinase PF02816.18 EKX52575.1 - 2.5e-34 119.0 0.2 2.7e-34 118.9 0.2 1.0 1 0 0 1 1 1 1 Alpha-kinase family DIPSY PF11763.8 EKX52575.1 - 0.024 14.8 0.0 0.024 14.8 0.0 1.2 1 0 0 1 1 1 0 Cell-wall adhesin ligand-binding C-terminal HALZ PF02183.18 EKX52576.1 - 0.17 12.1 6.9 0.12 12.6 1.5 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Rota_VP2 PF05087.12 EKX52576.1 - 0.58 8.2 4.0 0.75 7.9 4.0 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein Atg14 PF10186.9 EKX52576.1 - 3.5 6.6 11.3 2.4 7.2 10.1 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4612 PF15389.6 EKX52576.1 - 6.2 7.9 14.2 0.69 11.0 8.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4612) Beta_helix PF13229.6 EKX52577.1 - 6.5e-07 29.3 0.1 8.6e-06 25.7 0.0 2.3 2 0 0 2 2 2 1 Right handed beta helix region DUF2256 PF10013.9 EKX52578.1 - 6.2e-23 80.6 12.2 7.6e-23 80.4 12.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) YhfH PF14149.6 EKX52578.1 - 0.0055 16.7 0.1 0.0055 16.7 0.1 1.6 2 0 0 2 2 2 1 YhfH-like protein zf-MYND PF01753.18 EKX52578.1 - 0.0066 16.5 0.6 0.012 15.7 0.6 1.5 1 1 0 1 1 1 1 MYND finger zf-HIT PF04438.16 EKX52578.1 - 0.066 13.1 3.9 1.2 9.1 0.1 2.2 2 0 0 2 2 2 0 HIT zinc finger zf-trcl PF13451.6 EKX52578.1 - 0.7 9.8 7.9 1.1 9.2 7.9 1.3 1 1 0 1 1 1 0 Probable zinc-ribbon domain DUF2116 PF09889.9 EKX52578.1 - 0.85 9.6 2.9 5.9 7.0 2.9 2.0 1 1 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) AAA_31 PF13614.6 EKX52579.1 - 2.2e-42 145.0 0.0 2.1e-20 73.4 0.0 4.0 3 1 0 3 3 3 3 AAA domain CbiA PF01656.23 EKX52579.1 - 4.1e-24 85.1 0.0 7.9e-12 45.3 0.0 2.5 2 0 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 EKX52579.1 - 6.5e-14 52.0 4.3 2.5e-06 27.1 0.5 3.1 4 0 0 4 4 4 2 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 EKX52579.1 - 8.9e-10 38.4 0.1 0.00035 20.1 0.0 2.7 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 EKX52579.1 - 6.3e-09 35.5 0.1 0.0044 16.3 0.0 2.9 3 0 0 3 3 3 2 ATPase MipZ ArsA_ATPase PF02374.15 EKX52579.1 - 8.3e-09 35.0 0.3 0.00011 21.5 0.0 3.0 3 0 0 3 3 3 2 Anion-transporting ATPase VirC1 PF07015.11 EKX52579.1 - 6.4e-07 28.9 0.5 0.0083 15.5 0.2 3.5 4 0 0 4 4 4 2 VirC1 protein CBP_BcsQ PF06564.12 EKX52579.1 - 2.1e-06 27.4 0.0 0.0051 16.3 0.0 4.0 4 0 0 4 4 4 1 Cellulose biosynthesis protein BcsQ CLP1_P PF16575.5 EKX52579.1 - 0.00082 19.2 0.3 0.7 9.7 0.0 3.7 4 0 0 4 4 4 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 EKX52579.1 - 0.0051 15.8 0.4 3.3 6.6 0.1 2.6 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB LpxK PF02606.14 EKX52579.1 - 0.021 13.9 0.3 0.16 11.0 0.1 2.0 2 0 0 2 2 2 0 Tetraacyldisaccharide-1-P 4'-kinase FTHFS PF01268.19 EKX52579.1 - 0.23 9.6 0.9 5.1 5.2 0.1 2.1 2 0 0 2 2 2 0 Formate--tetrahydrofolate ligase Exo_endo_phos PF03372.23 EKX52580.1 - 7.3e-06 25.7 0.0 1.4e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Glyoxalase_4 PF13669.6 EKX52581.1 - 1.9e-18 66.7 0.0 2.6e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 EKX52581.1 - 0.00041 20.5 0.0 0.00077 19.7 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PDZ PF00595.24 EKX52584.1 - 5.8e-08 33.0 0.0 1e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX52584.1 - 3.8e-05 23.9 0.0 8.4e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX52584.1 - 0.00021 21.1 0.0 0.00042 20.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain DUF1152 PF06626.12 EKX52586.1 - 3.5e-09 36.3 0.1 6.9e-09 35.3 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1152) Ion_trans PF00520.31 EKX52587.1 - 2e-116 387.5 75.1 9e-39 133.2 15.6 4.3 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 EKX52587.1 - 0.0011 17.8 2.5 0.0011 17.8 2.5 5.9 5 1 1 6 6 6 3 Polycystin cation channel ISK_Channel PF02060.15 EKX52587.1 - 0.095 12.4 0.8 13 5.5 0.0 3.0 2 0 0 2 2 2 0 Slow voltage-gated potassium channel COX16 PF14138.6 EKX52587.1 - 0.095 13.2 1.6 0.47 11.0 1.6 2.2 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 GPHH PF16905.5 EKX52587.1 - 0.17 11.6 0.0 0.57 10.0 0.0 2.0 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated WW PF00397.26 EKX52588.1 - 5.4e-08 32.8 4.0 6.5e-06 26.1 1.1 2.9 2 0 0 2 2 2 2 WW domain FAM183 PF14886.6 EKX52588.1 - 0.011 16.5 0.1 0.033 14.9 0.1 1.8 1 0 0 1 1 1 0 FAM183A and FAM183B related RasGAP_C PF03836.15 EKX52588.1 - 0.12 12.6 1.1 0.22 11.7 1.1 1.4 1 0 0 1 1 1 0 RasGAP C-terminus RGS12_usC PF16612.5 EKX52588.1 - 0.73 10.3 4.1 0.22 12.0 0.9 1.9 2 1 0 2 2 2 0 C-terminal unstructured region of RGS12 G-patch PF01585.23 EKX52590.1 - 4.9e-10 39.1 0.2 1.2e-09 37.9 0.2 1.7 1 0 0 1 1 1 1 G-patch domain zf-U11-48K PF05253.12 EKX52590.1 - 4.3e-05 23.3 2.8 8.2e-05 22.4 2.8 1.5 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger G-patch_2 PF12656.7 EKX52590.1 - 0.02 15.0 0.0 0.053 13.6 0.0 1.7 1 0 0 1 1 1 0 G-patch domain TPR_1 PF00515.28 EKX52593.1 - 1.1e-06 28.2 0.1 2.3e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX52593.1 - 4e-06 26.6 0.1 1e-05 25.4 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX52593.1 - 6.4e-06 26.2 0.0 0.15 12.5 0.0 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX52593.1 - 1.5e-05 24.8 0.3 4.3e-05 23.3 0.3 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX52593.1 - 3.5e-05 24.3 0.2 8.2e-05 23.2 0.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX52593.1 - 0.011 16.5 0.2 0.077 13.9 0.1 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EKX52593.1 - 0.02 14.9 0.2 0.068 13.2 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 EKX52593.1 - 0.021 14.9 0.1 0.058 13.5 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX52593.1 - 0.022 15.3 1.2 0.04 14.4 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EKX52593.1 - 0.023 14.4 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 TPR repeat TPR_12 PF13424.6 EKX52593.1 - 0.026 14.8 2.4 0.027 14.8 0.6 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Vps39_1 PF10366.9 EKX52593.1 - 0.057 13.7 0.3 0.66 10.3 0.0 2.2 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Cnn_1N PF07989.11 EKX52593.1 - 0.72 10.1 7.8 6 7.1 0.5 3.5 4 0 0 4 4 4 0 Centrosomin N-terminal motif 1 TPR_20 PF14561.6 EKX52593.1 - 1.4 9.3 5.0 19 5.7 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF3567 PF12091.8 EKX52594.1 - 0.036 14.2 0.0 0.086 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3567) UQ_con PF00179.26 EKX52595.1 - 1.8e-37 128.1 0.0 2.4e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EKX52595.1 - 0.00037 20.2 0.0 0.00055 19.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B DUF218 PF02698.17 EKX52596.1 - 1.6e-10 41.1 0.0 1.6e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain EMP24_GP25L PF01105.24 EKX52597.1 - 1.5e-42 145.6 0.2 1.6e-42 145.5 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF3536 PF12055.8 EKX52597.1 - 0.028 13.8 0.2 0.044 13.1 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3536) MIB_HERC2 PF06701.13 EKX52599.1 - 0.00029 21.0 0.1 0.0007 19.8 0.1 1.7 1 0 0 1 1 1 1 Mib_herc2 IQ PF00612.27 EKX52599.1 - 0.18 11.7 5.3 1.8 8.6 0.2 3.4 3 0 0 3 3 3 0 IQ calmodulin-binding motif AAA_6 PF12774.7 EKX52600.1 - 9.9e-157 521.0 0.0 2.2e-156 519.9 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EKX52600.1 - 9.9e-120 400.3 5.7 9.9e-120 400.3 5.7 4.3 5 1 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 EKX52600.1 - 3e-115 386.0 9.7 3e-115 386.0 9.7 3.0 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.7 EKX52600.1 - 6.5e-101 337.0 0.0 2e-100 335.4 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EKX52600.1 - 1.4e-84 282.7 0.0 5.3e-84 280.8 0.0 2.1 1 0 0 1 1 1 1 ATP-binding dynein motor region Dynein_C PF18199.1 EKX52600.1 - 1.7e-82 277.1 0.5 1.7e-82 277.1 0.5 2.5 3 0 0 3 3 2 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 EKX52600.1 - 5.6e-72 241.0 0.2 2.3e-66 222.8 0.0 3.8 3 0 0 3 3 3 2 P-loop containing dynein motor region MT PF12777.7 EKX52600.1 - 5.3e-68 229.6 13.1 1.2e-67 228.4 13.1 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 EKX52600.1 - 9.7e-55 184.8 0.1 3.3e-54 183.1 0.1 2.0 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EKX52600.1 - 3.1e-43 146.6 0.0 4.1e-42 143.0 0.0 3.0 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 EKX52600.1 - 8.3e-26 90.6 0.0 5.3e-08 33.0 0.0 5.6 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 EKX52600.1 - 4.1e-22 78.7 0.4 8e-21 74.5 0.0 3.4 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EKX52600.1 - 1.3e-15 57.4 0.0 5e-15 55.5 0.0 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 EKX52600.1 - 9.9e-09 35.7 1.7 0.4 11.1 0.1 5.7 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EKX52600.1 - 1.8e-07 31.5 0.5 1 9.7 0.0 6.3 6 0 0 6 6 5 2 AAA domain AAA_16 PF13191.6 EKX52600.1 - 0.00057 20.3 12.2 4.1 7.8 0.0 7.4 6 2 1 7 7 7 1 AAA ATPase domain AAA_30 PF13604.6 EKX52600.1 - 0.0021 17.8 1.7 7.2 6.3 0.2 3.8 4 0 0 4 4 3 0 AAA domain RsgA_GTPase PF03193.16 EKX52600.1 - 0.0029 17.6 0.0 0.077 12.9 0.0 3.2 3 0 0 3 3 3 1 RsgA GTPase ABC_tran PF00005.27 EKX52600.1 - 0.0033 17.9 4.2 1.1 9.8 0.0 5.2 5 0 0 5 5 4 1 ABC transporter DHR10 PF18595.1 EKX52600.1 - 0.0067 16.5 18.1 0.0093 16.0 4.6 4.1 2 0 0 2 2 2 1 Designed helical repeat protein 10 domain DUF853 PF05872.12 EKX52600.1 - 0.008 14.8 1.5 5.7 5.4 0.0 3.3 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF853) BST2 PF16716.5 EKX52600.1 - 0.01 16.4 2.5 0.11 13.1 2.5 2.9 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 AAA_29 PF13555.6 EKX52600.1 - 0.04 13.7 0.1 3.5 7.4 0.0 3.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_18 PF13238.6 EKX52600.1 - 0.043 14.4 0.1 2.3 8.8 0.0 3.7 3 0 0 3 3 3 0 AAA domain DUF2096 PF09869.9 EKX52600.1 - 0.059 13.4 1.0 0.69 10.0 0.4 3.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) RNA_helicase PF00910.22 EKX52600.1 - 0.07 13.5 0.5 20 5.6 0.0 3.3 3 0 0 3 3 2 0 RNA helicase AAA_24 PF13479.6 EKX52600.1 - 0.15 11.8 4.1 2 8.1 0.4 3.6 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 EKX52600.1 - 0.52 9.3 4.6 0.95 8.5 0.3 3.2 4 0 0 4 4 3 0 Type II/IV secretion system protein FlaC_arch PF05377.11 EKX52600.1 - 1.2 9.6 5.9 1.8 9.0 0.3 4.0 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) SesA PF17107.5 EKX52600.1 - 2.4 8.4 13.2 3.9 7.7 0.1 5.6 4 0 0 4 4 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases RCC1 PF00415.18 EKX52601.1 - 1.7e-27 95.8 2.7 2.7e-07 31.1 0.0 4.5 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX52601.1 - 1.7e-14 53.1 8.4 2e-06 27.4 0.0 4.8 4 1 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat zf-CCHC_3 PF13917.6 EKX52603.1 - 0.0016 18.4 0.6 0.0052 16.7 0.6 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EKX52603.1 - 7.6 6.5 10.1 0.44 10.4 4.6 1.9 2 0 0 2 2 2 0 Zinc knuckle TMEM126 PF07114.11 EKX52604.1 - 0.021 14.2 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 126 Phage_Arf PF17585.2 EKX52604.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Accessory recombination function protein Ran_BP1 PF00638.18 EKX52606.1 - 3.1e-16 59.7 0.1 1.6e-15 57.4 0.1 2.1 2 0 0 2 2 2 1 RanBP1 domain SAM_1 PF00536.30 EKX52606.1 - 8.7e-11 42.1 0.2 1.7e-10 41.2 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RRM_1 PF00076.22 EKX52606.1 - 2.1e-09 37.1 0.0 6.7e-09 35.4 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAM_2 PF07647.17 EKX52606.1 - 1.4e-06 28.3 0.4 3e-06 27.2 0.4 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) WXG100 PF06013.12 EKX52606.1 - 0.58 10.4 3.3 9.3 6.6 0.1 3.1 3 0 0 3 3 3 0 Proteins of 100 residues with WXG WD40 PF00400.32 EKX52607.1 - 7.2e-15 55.1 0.4 0.073 14.0 0.1 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX52607.1 - 2e-08 34.4 0.4 0.26 11.6 0.0 4.5 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EKX52607.1 - 0.00042 20.2 0.2 0.51 10.2 0.1 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 EKX52607.1 - 0.011 13.8 0.2 0.022 12.8 0.1 1.5 2 0 0 2 2 2 0 IKI3 family Frtz PF11768.8 EKX52607.1 - 0.02 13.2 0.0 0.034 12.4 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Pkinase PF00069.25 EKX52608.1 - 9.2e-54 182.6 0.2 1.3e-53 182.0 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX52608.1 - 5.8e-30 104.4 1.5 2.6e-29 102.3 1.5 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.16 EKX52608.1 - 0.0022 18.1 0.0 0.006 16.7 0.0 1.7 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 EKX52608.1 - 0.0034 17.0 0.2 0.0068 16.0 0.2 1.5 1 0 0 1 1 1 1 RIO1 family DUF5100 PF17029.5 EKX52608.1 - 0.035 14.0 0.6 0.081 12.8 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5100) PKD_channel PF08016.12 EKX52609.1 - 0.00035 19.4 3.2 0.0025 16.5 0.0 3.0 2 1 1 3 3 3 2 Polycystin cation channel SAM_1 PF00536.30 EKX52610.1 - 9.4e-18 64.4 0.6 7.6e-11 42.3 0.0 2.7 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EKX52610.1 - 1.1e-17 63.9 0.7 1e-09 38.3 0.0 2.8 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) PARP PF00644.20 EKX52610.1 - 0.00072 19.2 0.0 0.25 10.9 0.0 2.9 3 0 0 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain fn3 PF00041.21 EKX52610.1 - 0.007 16.7 0.0 0.022 15.1 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III domain SAM_Ste50p PF09235.10 EKX52610.1 - 0.021 15.1 0.1 0.057 13.7 0.1 1.7 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Presenilin PF01080.17 EKX52610.1 - 0.67 8.6 5.1 1.8 7.2 5.1 1.6 1 0 0 1 1 1 0 Presenilin Myb_DNA-binding PF00249.31 EKX52612.1 - 8.8e-32 109.1 2.9 9.2e-16 57.8 0.6 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX52612.1 - 9.1e-25 86.7 4.7 1.3e-17 63.8 0.3 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EKX52612.1 - 5.3e-06 26.4 0.0 0.0023 17.9 0.0 2.3 2 0 0 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EKX52612.1 - 1.3e-05 25.0 0.2 0.0031 17.4 0.1 2.3 1 1 1 2 2 2 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EKX52612.1 - 0.0017 18.5 0.3 0.95 9.7 0.0 2.3 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_2 PF08914.11 EKX52612.1 - 0.02 15.1 1.1 0.46 10.7 0.2 3.0 1 1 1 2 2 2 0 Rap1 Myb domain HEAT_2 PF13646.6 EKX52613.1 - 7.8e-05 23.0 0.1 0.074 13.5 0.0 3.6 1 1 2 3 3 3 3 HEAT repeats HEAT PF02985.22 EKX52613.1 - 0.0033 17.6 2.4 2.4 8.6 0.0 4.2 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 EKX52613.1 - 0.035 14.6 0.7 0.29 11.7 0.1 2.8 3 0 0 3 3 3 0 HEAT-like repeat CNOT11 PF10155.9 EKX52614.1 - 2.3e-54 182.9 7.0 2.3e-54 182.9 7.0 1.7 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 11 CLASP_N PF12348.8 EKX52615.1 - 1.2e-15 57.7 0.7 2.2e-15 56.8 0.7 1.4 1 0 0 1 1 1 1 CLASP N terminal Rx_N PF18052.1 EKX52616.1 - 0.017 15.4 1.4 0.54 10.6 0.0 2.1 2 0 0 2 2 2 0 Rx N-terminal domain DUF4200 PF13863.6 EKX52616.1 - 0.55 10.6 6.3 0.71 10.3 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Octopine_DH PF02317.17 EKX52617.1 - 0.092 12.8 0.2 0.11 12.6 0.2 1.2 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain RNA_polI_A34 PF08208.11 EKX52617.1 - 1.1 9.2 21.8 1.5 8.9 21.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Vfa1 PF08432.10 EKX52617.1 - 3.7 7.8 21.7 4.7 7.5 21.7 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF5041 PF16444.5 EKX52617.1 - 5.3 7.3 8.1 4.6 7.5 6.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5041) Silic_transp PF03842.13 EKX52617.1 - 8.2 4.6 6.4 9.6 4.4 6.4 1.0 1 0 0 1 1 1 0 Silicon transporter RR_TM4-6 PF06459.12 EKX52617.1 - 8.3 6.1 16.4 8.8 6.1 16.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 EKX52617.1 - 8.6 4.5 17.2 9.3 4.4 17.2 1.0 1 0 0 1 1 1 0 CDC45-like protein LpxB PF02684.15 EKX52618.1 - 1.9e-72 244.2 0.0 2.3e-72 243.9 0.0 1.0 1 0 0 1 1 1 1 Lipid-A-disaccharide synthetase MAF_flag10 PF01973.18 EKX52618.1 - 0.021 14.5 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF115 Chromo PF00385.24 EKX52619.1 - 1.4e-12 47.3 0.3 2e-12 46.8 0.3 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 EKX52619.1 - 0.0052 16.6 0.0 0.0064 16.3 0.0 1.1 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Mtf2_C PF14061.6 EKX52619.1 - 0.046 13.9 0.1 0.065 13.4 0.1 1.4 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 C2 PF00168.30 EKX52620.1 - 1.6e-17 63.7 0.0 1.7e-17 63.6 0.0 1.0 1 0 0 1 1 1 1 C2 domain Med13_C PF06333.12 EKX52621.1 - 1.1e-06 28.2 0.0 1.1e-06 28.2 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal domain BAG6 PF12057.8 EKX52621.1 - 0.063 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 BCL2-associated athanogene 6 DUF4821 PF16092.5 EKX52622.1 - 6.3e-48 163.7 0.1 1.2e-41 143.1 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4821) Pyr_redox_2 PF07992.14 EKX52622.1 - 1.3e-17 64.0 0.0 3.3e-16 59.4 0.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EKX52622.1 - 0.0041 16.0 0.8 0.12 11.2 0.0 2.5 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.27 EKX52622.1 - 0.0061 17.1 1.7 0.018 15.6 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EKX52622.1 - 0.011 15.4 4.7 1.2 8.6 0.0 2.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EKX52622.1 - 0.012 14.8 0.0 0.11 11.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ABC_transp_aux PF09822.9 EKX52622.1 - 0.2 11.1 2.0 0.94 8.9 2.7 1.7 2 0 0 2 2 2 0 ABC-type uncharacterized transport system Ribosomal_L9_N PF01281.19 EKX52623.1 - 2.7e-18 65.2 0.0 5e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 EKX52623.1 - 1.7e-17 63.7 0.0 2.9e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain LRR_8 PF13855.6 EKX52624.1 - 1e-28 98.9 27.7 3.4e-08 33.1 4.1 4.0 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 EKX52624.1 - 9.1e-20 70.4 9.7 6.8e-06 26.3 0.3 4.3 1 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX52624.1 - 1e-08 34.5 16.0 0.14 12.8 0.7 6.7 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.6 EKX52624.1 - 7.1e-06 25.7 11.5 3.9 7.8 0.0 6.6 7 0 0 7 7 7 3 Leucine Rich repeat LRR_9 PF14580.6 EKX52624.1 - 0.00067 19.2 3.4 0.96 8.9 0.1 3.1 1 1 2 3 3 3 3 Leucine-rich repeat LRR_5 PF13306.6 EKX52624.1 - 0.057 13.4 0.1 0.54 10.2 0.1 2.1 1 1 1 2 2 2 0 BspA type Leucine rich repeat region (6 copies) NAD_binding_1 PF00175.21 EKX52625.1 - 2.5e-31 108.6 0.0 4e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EKX52625.1 - 4.9e-26 91.0 0.0 2.2e-15 56.8 0.0 2.5 1 1 1 2 2 2 2 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EKX52625.1 - 3.2e-08 33.8 0.0 1.3e-07 31.9 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 EKX52625.1 - 0.034 14.4 0.0 0.41 10.9 0.0 2.2 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Aconitase_B_N PF11791.8 EKX52625.1 - 0.04 14.0 0.1 0.063 13.3 0.1 1.2 1 0 0 1 1 1 0 Aconitate B N-terminal domain Nuc_sug_transp PF04142.15 EKX52627.1 - 1.3e-93 313.6 18.8 1.6e-93 313.3 18.8 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 EKX52627.1 - 5.1e-08 32.5 19.5 7.3e-08 32.0 19.5 1.4 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 EKX52627.1 - 2.5e-07 30.2 3.0 2.5e-07 30.2 3.0 2.4 2 1 0 2 2 2 1 Purine nucleobase transmembrane transport EamA PF00892.20 EKX52627.1 - 7.2e-06 26.2 3.1 7.2e-06 26.2 3.1 2.5 2 0 0 2 2 2 1 EamA-like transporter family Pkinase PF00069.25 EKX52629.1 - 9.1e-69 231.7 0.1 1e-68 231.5 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX52629.1 - 7.6e-34 117.2 0.0 1e-33 116.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX52629.1 - 0.00085 18.7 0.0 0.0022 17.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EKX52629.1 - 0.0019 17.1 0.2 0.0042 15.9 0.1 1.5 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EKX52629.1 - 0.01 14.8 0.7 0.015 14.3 0.7 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RNA_pol_Rpb1_5 PF04998.17 EKX52629.1 - 0.19 11.1 0.3 0.25 10.7 0.3 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 HORMA PF02301.18 EKX52630.1 - 6.3e-10 39.0 0.0 7.6e-10 38.7 0.0 1.3 1 1 0 1 1 1 1 HORMA domain ATG101 PF07855.12 EKX52630.1 - 0.084 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 101 Ribosomal_S17e PF00833.18 EKX52630.1 - 0.17 11.8 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal S17 Glyco_hyd_65N_2 PF14498.6 EKX52632.1 - 0.035 14.0 1.8 0.046 13.6 1.8 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF148 PF02520.17 EKX52632.1 - 0.18 12.0 11.8 0.25 11.5 1.2 3.1 2 1 1 3 3 3 0 Domain of unknown function DUF148 SAM_1 PF00536.30 EKX52633.1 - 1.4e-08 35.1 0.0 2.6e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EKX52633.1 - 1.5e-08 34.6 0.0 2.9e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SPRY PF00622.28 EKX52633.1 - 4.2e-05 23.6 0.0 9.6e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 SPRY domain PH PF00169.29 EKX52633.1 - 0.096 13.2 0.0 0.28 11.7 0.0 1.9 1 1 0 1 1 1 0 PH domain Na_H_antiport_2 PF13726.6 EKX52633.1 - 0.14 12.3 0.1 0.24 11.6 0.1 1.3 1 0 0 1 1 1 0 Na+-H+ antiporter family Form-deh_trans PF09163.11 EKX52635.1 - 0.15 11.8 0.9 5.6 6.8 0.7 2.3 2 0 0 2 2 2 0 Formate dehydrogenase N, transmembrane ClpS PF02617.17 EKX52636.1 - 6.5e-07 29.1 0.1 7e-05 22.5 0.1 2.1 2 0 0 2 2 2 2 ATP-dependent Clp protease adaptor protein ClpS Chal_sti_synt_C PF02797.15 EKX52636.1 - 0.18 11.8 0.1 7.8 6.5 0.0 2.2 2 0 0 2 2 2 0 Chalcone and stilbene synthases, C-terminal domain NIF PF03031.18 EKX52637.1 - 4.9e-22 78.4 0.1 8.9e-22 77.5 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Biotin_lipoyl PF00364.22 EKX52637.1 - 0.062 13.1 0.0 0.21 11.4 0.0 1.9 1 0 0 1 1 1 0 Biotin-requiring enzyme BRCT_3 PF18428.1 EKX52637.1 - 0.077 13.1 0.1 0.49 10.5 0.1 2.1 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 EKX52637.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain Leu_leader PF08054.11 EKX52638.1 - 0.25 10.9 3.0 0.82 9.3 3.0 1.9 1 0 0 1 1 1 0 Leucine operon leader peptide DUF4746 PF15928.5 EKX52638.1 - 1.5 8.1 8.4 5.3 6.4 5.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) PQQ_3 PF13570.6 EKX52641.1 - 0.022 15.2 0.0 11 6.6 0.0 3.6 4 0 0 4 4 4 0 PQQ-like domain PQQ_2 PF13360.6 EKX52641.1 - 0.15 11.7 0.1 0.96 9.0 0.0 2.2 2 1 0 2 2 2 0 PQQ-like domain Poxvirus_B22R PF04395.12 EKX52642.1 - 0.26 10.8 3.2 0.33 10.4 0.1 2.1 2 0 0 2 2 2 0 Poxvirus B22R protein MFS_5 PF05631.14 EKX52644.1 - 3.8e-83 279.3 12.2 2.8e-81 273.2 12.2 2.6 1 1 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 EKX52644.1 - 1.7e-17 63.4 32.1 6.9e-15 54.8 15.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EKX52644.1 - 0.00017 20.6 2.6 0.00017 20.6 2.6 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter Toxin_31 PF08119.11 EKX52644.1 - 0.11 12.2 0.3 0.11 12.2 0.3 1.9 2 0 0 2 2 2 0 Scorpion acidic alpha-KTx toxin family DUF5090 PF17009.5 EKX52644.1 - 1.3 9.0 5.0 11 5.9 2.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5090) zf-C3Hc3H PF13891.6 EKX52647.1 - 0.00033 21.0 1.0 0.00084 19.7 1.0 1.7 1 0 0 1 1 1 1 Potential DNA-binding domain Adaptin_binding PF10199.9 EKX52647.1 - 0.022 15.3 5.4 0.22 12.1 5.4 2.3 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Spore_coat_CotO PF14153.6 EKX52647.1 - 3.2 7.7 11.7 0.48 10.3 4.8 2.1 2 0 0 2 2 2 0 Spore coat protein CotO Baculo_PEP_C PF04513.12 EKX52648.1 - 0.72 9.9 9.0 1.4 8.9 0.7 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 EKX52648.1 - 2.1 7.2 39.2 0.24 10.2 7.1 3.0 1 1 1 3 3 3 0 Spc7 kinetochore protein DUF4407 PF14362.6 EKX52648.1 - 5.6 6.2 29.2 4.8 6.4 20.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 EKX52648.1 - 8 7.0 13.0 24 5.5 1.4 3.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF2207 PF09972.9 EKX52649.1 - 4.6e-06 25.7 1.0 6.7e-06 25.1 1.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) TraG_N PF07916.11 EKX52649.1 - 0.0068 15.3 0.1 0.0089 14.9 0.1 1.2 1 0 0 1 1 1 1 TraG-like protein, N-terminal region CobD_Cbib PF03186.13 EKX52649.1 - 0.018 14.3 1.8 0.04 13.1 0.2 2.0 2 0 0 2 2 2 0 CobD/Cbib protein CitMHS PF03600.16 EKX52649.1 - 0.022 14.0 3.6 0.034 13.4 3.6 1.2 1 0 0 1 1 1 0 Citrate transporter Pex24p PF06398.11 EKX52649.1 - 0.033 13.2 0.2 0.055 12.5 0.2 1.4 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin PDZ_2 PF13180.6 EKX52649.1 - 0.051 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 PDZ domain DUF3043 PF11241.8 EKX52649.1 - 0.15 12.1 2.4 0.37 10.8 2.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Wzy_C PF04932.15 EKX52649.1 - 0.24 11.0 5.4 0.39 10.3 5.4 1.3 1 0 0 1 1 1 0 O-Antigen ligase Ac81 PF05820.11 EKX52649.1 - 0.53 9.8 12.3 0.87 9.1 12.3 1.4 1 0 0 1 1 1 0 Baculoviridae AC81 DUF2070 PF09843.9 EKX52649.1 - 4.6 5.4 11.2 6.5 4.9 11.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TUDOR_5 PF18359.1 EKX52651.1 - 3e-11 42.8 2.7 0.00013 21.6 0.4 2.3 2 0 0 2 2 2 2 Histone methyltransferase Tudor domain 1 LBR_tudor PF09465.10 EKX52651.1 - 2.7e-09 36.7 0.0 0.0017 18.1 0.0 2.4 2 0 0 2 2 2 2 Lamin-B receptor of TUDOR domain DUF1325 PF07039.11 EKX52651.1 - 3.2e-09 36.9 0.0 8.7e-05 22.6 0.0 2.4 1 1 1 2 2 2 2 SGF29 tudor-like domain Tudor_3 PF18115.1 EKX52651.1 - 2.4e-08 33.7 0.2 0.0011 18.7 0.0 2.4 2 0 0 2 2 2 2 DNA repair protein Crb2 Tudor domain 53-BP1_Tudor PF09038.10 EKX52651.1 - 5.4e-06 26.4 0.5 0.01 15.8 0.0 2.5 1 1 1 2 2 2 2 Tumour suppressor p53-binding protein-1 Tudor PaREP1 PF05942.11 EKX52651.1 - 8.1e-06 25.8 30.2 0.4 10.6 2.0 4.6 4 0 0 4 4 4 4 Archaeal PaREP1/PaREP8 family DUF4537 PF15057.6 EKX52651.1 - 1.3e-05 25.2 0.1 7.6e-05 22.7 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4537) YfdX PF10938.8 EKX52651.1 - 8.3e-05 22.6 31.6 0.92 9.4 1.0 5.1 5 0 0 5 5 5 4 YfdX protein DUF357 PF04010.13 EKX52651.1 - 0.0005 20.1 7.7 20 5.3 0.1 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF357) DUF2379 PF09543.10 EKX52651.1 - 0.0016 18.6 20.2 3.8 7.7 0.6 4.4 4 0 0 4 4 4 4 Protein of unknown function (DUF2379) Tudor_2 PF18104.1 EKX52651.1 - 0.013 15.2 1.4 0.97 9.2 0.2 2.5 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain HEPN PF05168.14 EKX52651.1 - 0.016 15.3 29.1 2.3 8.4 1.3 4.6 5 0 0 5 5 5 0 HEPN domain Agenet PF05641.12 EKX52651.1 - 0.027 14.9 0.0 2.5 8.7 0.0 3.0 3 0 0 3 3 3 0 Agenet domain DUF4175 PF13779.6 EKX52651.1 - 0.058 11.3 62.8 0.88 7.4 13.0 4.1 1 1 2 4 4 4 0 Domain of unknown function (DUF4175) ArnB_C PF18677.1 EKX52651.1 - 0.13 12.4 10.9 11 6.2 0.5 4.3 1 1 3 4 4 4 0 Archaellum regulatory network B, C-terminal domain PhoU PF01895.19 EKX52651.1 - 3.1 8.3 11.8 1.6e+02 2.8 0.2 5.0 5 0 0 5 5 5 0 PhoU domain V-SNARE PF05008.15 EKX52651.1 - 3.8 7.9 23.6 18 5.8 0.6 4.7 5 0 0 5 5 5 0 Vesicle transport v-SNARE protein N-terminus Sarcolipin PF05366.11 EKX52654.1 - 0.22 11.3 1.4 0.33 10.7 1.4 1.2 1 0 0 1 1 1 0 Sarcolipin Methyltransf_7 PF03492.15 EKX52655.1 - 1.5e-26 93.4 0.0 2.2e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase SHOCT PF09851.9 EKX52655.1 - 0.03 14.1 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 Short C-terminal domain zf-C3HC4_2 PF13923.6 EKX52656.1 - 2.8e-10 39.9 9.4 4.3e-10 39.3 9.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EKX52656.1 - 4.9e-10 39.4 8.6 1.2e-09 38.2 8.6 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EKX52656.1 - 1.4e-09 37.8 4.3 1.4e-09 37.8 4.3 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EKX52656.1 - 3.7e-08 33.1 11.5 5.1e-08 32.7 11.5 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX52656.1 - 4.5e-08 32.8 8.7 7.5e-08 32.1 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EKX52656.1 - 1.2e-07 31.9 9.2 2e-07 31.2 9.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EKX52656.1 - 1.3e-07 31.4 9.7 2.3e-07 30.7 9.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EKX52656.1 - 1e-06 28.5 11.6 1.7e-06 27.8 11.6 1.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 EKX52656.1 - 1.2e-05 25.0 5.4 1.4e-05 24.9 5.4 1.1 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 EKX52656.1 - 0.00062 19.8 6.9 0.00074 19.6 6.9 1.1 1 0 0 1 1 1 1 zinc RING finger of MSL2 Zn_Tnp_IS91 PF14319.6 EKX52656.1 - 0.017 15.2 3.2 0.017 15.2 3.2 2.0 1 1 1 2 2 2 0 Transposase zinc-binding domain zf-RING_4 PF14570.6 EKX52656.1 - 0.022 14.6 11.1 0.17 11.7 11.2 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EKX52656.1 - 0.078 13.3 10.5 0.26 11.6 10.5 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain Rad50_zn_hook PF04423.14 EKX52656.1 - 0.32 10.9 3.6 3.7 7.5 0.3 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif Cys_rich_KTR PF14205.6 EKX52656.1 - 0.38 10.6 0.2 0.38 10.6 0.2 2.4 3 0 0 3 3 3 0 Cysteine-rich KTR zf-C3HC4_5 PF17121.5 EKX52656.1 - 0.63 10.0 15.5 2.9 7.9 1.0 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-WRNIP1_ubi PF18279.1 EKX52656.1 - 1.3 9.8 8.8 4.4 8.2 1.0 2.6 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain DUF1990 PF09348.10 EKX52657.1 - 6.9e-05 23.0 0.0 0.0001 22.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1990) Ank_2 PF12796.7 EKX52658.1 - 5.6e-10 39.7 0.0 5.9e-10 39.6 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX52658.1 - 8.2e-10 38.8 0.0 1.4e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX52658.1 - 7.6e-09 35.9 0.0 2.2e-08 34.5 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX52658.1 - 6.7e-05 23.2 0.0 0.00019 21.7 0.0 1.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EKX52658.1 - 0.00014 22.0 0.0 0.00031 20.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat INT_SG_DDX_CT_C PF15300.6 EKX52658.1 - 0.014 15.1 0.6 0.13 12.0 0.4 2.0 1 1 1 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus TraY PF05509.11 EKX52658.1 - 0.11 12.5 1.1 1.3 9.1 0.5 2.2 2 0 0 2 2 2 0 TraY domain DUF4602 PF15375.6 EKX52659.1 - 1.4e-11 44.8 23.8 1.4e-11 44.8 23.8 2.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4602) DUF2514 PF10721.9 EKX52659.1 - 0.51 10.4 5.0 1.3 9.0 5.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Pkinase PF00069.25 EKX52660.1 - 5.7e-68 229.1 0.0 6.6e-68 228.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX52660.1 - 2e-44 151.8 0.0 2.6e-44 151.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX52660.1 - 9.2e-05 21.4 0.0 0.00013 20.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EKX52660.1 - 0.00076 18.9 0.0 0.01 15.2 0.0 2.1 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 EKX52660.1 - 0.0076 16.2 0.3 0.044 13.7 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EKX52660.1 - 0.0088 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Haspin_kinase PF12330.8 EKX52660.1 - 0.092 11.7 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain LRR_6 PF13516.6 EKX52661.1 - 1.3e-19 68.5 9.8 9.4e-05 22.2 0.6 6.2 6 0 0 6 6 6 4 Leucine Rich repeat LRR_1 PF00560.33 EKX52661.1 - 4.9e-06 26.4 0.1 53 4.9 0.0 5.5 5 0 0 5 5 5 0 Leucine Rich Repeat Trypan_PARP PF05887.11 EKX52661.1 - 0.0064 16.5 4.6 0.0064 16.5 4.6 1.6 2 0 0 2 2 1 1 Procyclic acidic repetitive protein (PARP) LRR_4 PF12799.7 EKX52661.1 - 0.013 15.9 4.7 12 6.5 0.3 3.6 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) TFIIA PF03153.13 EKX52661.1 - 0.024 14.6 20.0 0.029 14.4 20.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fmp27 PF10344.9 EKX52661.1 - 0.025 12.7 2.4 0.031 12.4 2.4 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 CDC45 PF02724.14 EKX52661.1 - 0.037 12.3 16.5 0.046 12.0 16.5 1.1 1 0 0 1 1 1 0 CDC45-like protein BcsB PF03170.13 EKX52661.1 - 0.063 11.6 3.2 0.086 11.2 3.2 1.1 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit SID-1_RNA_chan PF13965.6 EKX52661.1 - 0.085 11.3 0.7 0.098 11.1 0.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 LRR_8 PF13855.6 EKX52661.1 - 0.54 10.1 5.8 4.1 7.3 2.1 3.6 2 1 1 3 3 3 0 Leucine rich repeat FHIPEP PF00771.20 EKX52661.1 - 0.73 8.2 6.0 0.12 10.8 2.5 1.4 2 0 0 2 2 2 0 FHIPEP family Folate_carrier PF01770.18 EKX52661.1 - 0.95 8.1 2.8 1.3 7.6 2.8 1.3 1 0 0 1 1 1 0 Reduced folate carrier EIIBC-GUT_N PF03612.14 EKX52661.1 - 1.1 9.0 12.2 2.2 8.0 12.2 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Ribosomal_L6e PF01159.19 EKX52661.1 - 1.3 9.5 16.6 0.43 11.1 0.6 2.2 2 0 0 2 2 2 0 Ribosomal protein L6e Serinc PF03348.15 EKX52661.1 - 2.1 7.2 4.4 0.23 10.4 0.5 1.4 2 0 0 2 2 2 0 Serine incorporator (Serinc) Ureide_permease PF07168.11 EKX52661.1 - 2.3 6.9 4.7 3.9 6.1 4.7 1.4 1 0 0 1 1 1 0 Ureide permease Presenilin PF01080.17 EKX52661.1 - 3.4 6.3 16.9 4.6 5.9 16.9 1.3 1 0 0 1 1 1 0 Presenilin NAD_binding_1 PF00175.21 EKX52661.1 - 6.2 7.5 8.4 1.1 9.9 0.2 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain MORN PF02493.20 EKX52662.1 - 0.0003 20.5 6.1 0.42 10.6 0.1 3.5 3 0 0 3 3 3 2 MORN repeat DUF4381 PF14316.6 EKX52662.1 - 0.017 15.4 2.0 0.029 14.6 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Synaptobrevin PF00957.21 EKX52662.1 - 0.17 11.7 0.4 0.31 10.9 0.4 1.3 1 0 0 1 1 1 0 Synaptobrevin LRR_9 PF14580.6 EKX52664.1 - 1.3e-10 41.1 1.9 1.1e-09 38.1 1.0 2.5 1 1 1 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 EKX52664.1 - 8.7e-07 29.2 7.7 0.0011 19.3 3.2 4.1 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX52664.1 - 0.00045 19.9 8.1 0.0031 17.2 2.5 2.9 2 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 EKX52664.1 - 0.14 12.3 0.7 0.8 9.9 0.1 2.7 2 0 0 2 2 2 0 Leucine Rich repeat FAM195 PF14799.6 EKX52664.1 - 0.5 10.7 3.4 0.39 11.1 0.4 2.3 2 1 0 2 2 2 0 FAM195 family Vfa1 PF08432.10 EKX52664.1 - 7 6.9 12.5 3.6 7.9 3.7 2.6 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 HEAT_2 PF13646.6 EKX52665.1 - 0.0037 17.6 1.3 0.023 15.1 0.9 2.0 1 1 0 1 1 1 1 HEAT repeats TTc_toxin_rep PF18807.1 EKX52665.1 - 0.02 14.7 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Tripartite Tc toxins repeat WW PF00397.26 EKX52666.1 - 1.8e-09 37.5 3.2 2.9e-09 36.9 3.2 1.3 1 0 0 1 1 1 1 WW domain Glyco_hyd_101C PF17451.2 EKX52666.1 - 0.019 15.2 3.4 0.028 14.7 3.4 1.5 1 1 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain RWP-RK PF02042.15 EKX52667.1 - 4.9e-18 64.9 0.3 1.1e-17 63.7 0.3 1.6 1 0 0 1 1 1 1 RWP-RK domain SPX PF03105.19 EKX52667.1 - 1.5e-07 31.7 17.4 0.0005 20.1 0.4 4.1 2 1 2 4 4 4 3 SPX domain MORN PF02493.20 EKX52668.1 - 9e-26 88.2 23.8 3.2e-05 23.5 2.6 7.0 7 0 0 7 7 7 6 MORN repeat CCDC53 PF10152.9 EKX52669.1 - 0.00032 21.2 3.4 0.00057 20.3 3.4 1.4 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex DUF1180 PF06679.12 EKX52669.1 - 0.016 15.6 0.9 0.024 15.1 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Ion_trans PF00520.31 EKX52669.1 - 0.016 14.4 0.1 0.028 13.7 0.1 1.3 1 0 0 1 1 1 0 Ion transport protein Pyr_redox_2 PF07992.14 EKX52670.1 - 3e-43 148.1 0.9 4e-43 147.7 0.9 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EKX52670.1 - 2.8e-15 56.5 0.1 1.3e-13 51.2 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EKX52670.1 - 9.9e-15 54.9 1.2 4.4e-11 43.2 0.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EKX52670.1 - 7.2e-13 48.5 0.0 8.2e-07 28.6 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EKX52670.1 - 2.5e-06 26.9 10.2 2.9e-06 26.6 2.2 3.0 2 2 1 3 3 3 1 FAD binding domain DAO PF01266.24 EKX52670.1 - 1.9e-05 24.4 3.0 0.00013 21.7 0.1 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EKX52670.1 - 2e-05 24.2 2.7 2e-05 24.2 2.7 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EKX52670.1 - 4e-05 22.5 0.5 0.00011 21.0 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 EKX52670.1 - 0.00012 21.3 1.7 0.0056 15.8 0.2 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EKX52670.1 - 0.00013 21.4 0.2 0.15 11.3 0.1 2.8 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EKX52670.1 - 0.00042 19.7 0.1 0.0009 18.6 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EKX52670.1 - 0.00054 20.1 2.5 0.018 15.3 0.5 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EKX52670.1 - 0.0012 18.2 0.5 0.069 12.4 0.0 2.9 3 0 0 3 3 3 1 Thi4 family K_oxygenase PF13434.6 EKX52670.1 - 0.002 17.3 0.1 1.2 8.2 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 EKX52670.1 - 0.0027 17.1 0.1 0.025 13.9 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EKX52670.1 - 0.003 17.5 0.6 0.73 9.7 0.0 2.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EKX52670.1 - 0.0033 17.9 0.8 2.7 8.5 0.1 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding XdhC_C PF13478.6 EKX52670.1 - 0.017 15.6 0.1 5.2 7.6 0.0 2.7 3 0 0 3 3 3 0 XdhC Rossmann domain Peptidase_C12 PF01088.21 EKX52671.1 - 1.6e-25 90.1 0.0 1.8e-25 90.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF1204 PF06721.11 EKX52672.1 - 0.063 12.7 0.9 0.76 9.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1204) Sec23_trunk PF04811.15 EKX52673.1 - 1.1e-21 77.6 0.0 1.6e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 EKX52673.1 - 1e-10 41.5 6.2 1.5e-09 37.7 5.5 2.5 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.15 EKX52673.1 - 2e-10 40.4 0.1 5.7e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EKX52673.1 - 2e-05 25.3 0.0 4.4e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-RanBP PF00641.18 EKX52673.1 - 0.077 12.3 0.4 0.19 11.1 0.4 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 EKX52673.1 - 0.093 12.1 0.5 0.9 9.0 0.0 2.7 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Mucin PF01456.17 EKX52675.1 - 3.2 7.7 23.6 1.8 8.5 9.8 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein ABC_tran PF00005.27 EKX52676.1 - 1.9e-27 96.5 0.1 4.1e-27 95.4 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EKX52676.1 - 2.5e-13 50.5 0.0 2.7e-11 43.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EKX52676.1 - 1.2e-07 31.4 0.1 8.3e-06 25.4 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EKX52676.1 - 1.2e-05 25.2 0.0 0.0046 16.7 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 EKX52676.1 - 0.0011 19.1 0.0 0.017 15.4 0.0 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit IstB_IS21 PF01695.17 EKX52676.1 - 0.0037 17.0 0.1 0.66 9.7 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_23 PF13476.6 EKX52676.1 - 0.0042 17.6 0.3 0.0081 16.7 0.1 1.5 1 1 0 1 1 1 1 AAA domain MukB PF04310.12 EKX52676.1 - 0.0043 16.9 0.1 0.0075 16.1 0.1 1.3 1 0 0 1 1 1 1 MukB N-terminal CobA_CobO_BtuR PF02572.15 EKX52676.1 - 0.043 14.1 0.0 0.074 13.3 0.0 1.4 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP NB-ARC PF00931.22 EKX52676.1 - 0.063 12.5 0.1 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.6 EKX52676.1 - 0.068 12.9 0.4 2 8.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 EKX52676.1 - 0.083 12.5 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 EKX52677.1 - 2.6e-24 86.3 0.0 5.7e-24 85.2 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EKX52677.1 - 2.8e-07 30.7 0.0 0.00053 19.9 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EKX52677.1 - 6.5e-05 22.8 0.0 0.004 16.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 EKX52677.1 - 0.00023 20.7 0.2 0.15 11.5 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EKX52677.1 - 0.0076 16.0 0.1 0.016 14.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 EKX52677.1 - 0.072 13.3 0.0 0.82 10.0 0.0 2.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EKX52677.1 - 0.12 12.9 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain BAR_3 PF16746.5 EKX52679.1 - 0.48 10.1 8.3 1.6 8.4 3.0 2.3 2 0 0 2 2 2 0 BAR domain of APPL family MCU PF04678.13 EKX52679.1 - 0.85 9.7 6.7 0.66 10.0 1.2 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF4446 PF14584.6 EKX52679.1 - 2.4 8.1 8.9 0.43 10.6 3.5 2.2 1 1 1 3 3 3 0 Protein of unknown function (DUF4446) CDC45 PF02724.14 EKX52680.1 - 2.9 6.1 23.2 4 5.6 23.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 EKX52680.1 - 3.3 7.0 49.2 6.1 6.1 49.2 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF572 PF04502.13 EKX52680.1 - 6.8 6.2 31.6 9.5 5.7 31.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Asp-B-Hydro_N PF05279.11 EKX52680.1 - 9.2 6.2 37.7 14 5.7 37.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CLPTM1 PF05602.12 EKX52681.1 - 2.2e-89 300.5 16.8 2e-84 284.1 2.6 2.0 1 1 1 2 2 2 2 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 EKX52681.1 - 0.0075 16.0 3.7 0.54 10.1 0.5 3.0 2 0 0 2 2 2 2 PQ loop repeat DoxX_2 PF13564.6 EKX52683.1 - 6.3 7.0 12.4 1.3 9.1 7.8 2.3 2 1 0 2 2 2 0 DoxX-like family R3H-assoc PF13902.6 EKX52686.1 - 1.5e-14 54.5 4.5 1.5e-14 54.5 4.5 1.8 2 0 0 2 2 2 1 R3H-associated N-terminal domain Pkinase PF00069.25 EKX52687.1 - 2.9e-44 151.4 0.0 2.1e-43 148.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX52687.1 - 2.8e-30 105.5 0.0 6.9e-30 104.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX52687.1 - 0.008 15.0 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EKX52687.1 - 0.0081 15.5 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EKX52687.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EKX52687.1 - 0.09 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.11 EKX52687.1 - 0.097 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase GAS PF13851.6 EKX52688.1 - 0.002 17.5 3.8 0.002 17.5 3.8 5.6 2 1 3 5 5 5 1 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EKX52688.1 - 0.0037 16.2 14.8 0.0037 16.2 14.8 4.1 2 1 2 4 4 4 3 Spc7 kinetochore protein ATG16 PF08614.11 EKX52688.1 - 0.011 16.0 6.7 0.011 16.0 6.7 6.1 2 1 3 5 5 4 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 EKX52688.1 - 0.011 16.2 14.5 0.011 16.2 14.5 4.2 2 1 1 4 4 4 0 Fez1 ADIP PF11559.8 EKX52688.1 - 0.017 15.2 3.7 0.017 15.2 3.7 5.6 3 3 1 5 5 5 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 EKX52688.1 - 0.18 11.8 23.3 0.044 13.8 2.3 4.7 3 3 1 4 4 4 0 Protein of unknown function (DUF1664) TRAF_BIRC3_bd PF16673.5 EKX52688.1 - 0.44 10.4 5.3 0.57 10.0 0.3 3.7 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain Lebercilin PF15619.6 EKX52688.1 - 0.51 10.0 47.7 1.1 8.8 15.4 4.0 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Prominin PF05478.11 EKX52688.1 - 3.3 5.6 19.3 0.059 11.3 11.9 1.8 2 1 0 2 2 2 0 Prominin Filament PF00038.21 EKX52688.1 - 3.4 7.1 46.5 0.11 12.1 35.0 3.3 2 1 1 3 3 3 0 Intermediate filament protein Golgin_A5 PF09787.9 EKX52688.1 - 4.9 6.5 51.5 0.056 12.9 14.9 3.6 2 1 1 3 3 3 0 Golgin subfamily A member 5 Ank_2 PF12796.7 EKX52689.1 - 1.3e-08 35.2 0.0 1.8e-05 25.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX52689.1 - 8.3e-08 32.4 0.1 8.5e-06 26.0 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX52689.1 - 5e-05 23.6 0.1 0.19 12.2 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 EKX52689.1 - 8.7e-05 22.6 0.0 0.87 10.4 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 EKX52689.1 - 0.01 16.4 0.0 7.8 7.2 0.0 2.7 1 1 2 3 3 3 0 Ankyrin repeats (many copies) EF-hand_1 PF00036.32 EKX52690.1 - 7.7e-16 56.4 4.3 1.4e-05 24.3 0.1 4.6 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 EKX52690.1 - 7.2e-14 52.0 18.8 4.7e-08 33.4 1.2 3.2 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EKX52690.1 - 4.6e-10 38.6 6.4 0.0087 15.9 0.0 4.7 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 EKX52690.1 - 2.6e-09 36.2 7.8 0.00023 20.5 0.0 4.4 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 EKX52690.1 - 2.5e-08 33.6 7.4 0.028 14.2 0.1 4.5 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX52690.1 - 2.8e-05 24.4 8.4 2.8 8.3 2.1 4.1 3 1 0 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region fn3 PF00041.21 EKX52691.1 - 2.1e-06 28.0 0.1 3.7e-06 27.2 0.1 1.5 1 1 0 1 1 1 1 Fibronectin type III domain BNR PF02012.20 EKX52691.1 - 0.39 10.9 1.5 0.54 10.5 0.1 2.1 2 0 0 2 2 2 0 BNR/Asp-box repeat Ferrochelatase PF00762.19 EKX52692.1 - 1.3e-107 359.6 0.0 1.5e-107 359.4 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase DFF40 PF09230.10 EKX52692.1 - 0.081 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa SET PF00856.28 EKX52694.1 - 3.7e-21 76.2 0.3 9.3e-20 71.7 0.3 2.1 1 1 0 1 1 1 1 SET domain AWS PF17907.1 EKX52694.1 - 9.8e-12 44.7 8.1 9.8e-12 44.7 8.1 2.9 3 0 0 3 3 3 1 AWS domain DUF600 PF04634.12 EKX52694.1 - 0.029 14.4 0.3 0.049 13.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF600 Med9 PF07544.13 EKX52695.1 - 1.2e-08 34.9 0.0 1.2e-08 34.9 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Cupin_8 PF13621.6 EKX52696.1 - 5.5e-06 26.3 0.1 0.0002 21.1 0.0 2.3 2 0 0 2 2 2 1 Cupin-like domain HAD_SAK_2 PF18143.1 EKX52696.1 - 0.0023 18.2 0.8 0.0076 16.6 0.1 2.2 2 0 0 2 2 2 1 HAD domain in Swiss Army Knife RNA repair proteins DUF2752 PF10825.8 EKX52696.1 - 0.013 15.6 0.3 0.029 14.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) JmjC PF02373.22 EKX52696.1 - 0.031 14.7 0.0 0.28 11.6 0.0 2.6 2 1 0 2 2 2 0 JmjC domain, hydroxylase VEGF_C PF14554.6 EKX52696.1 - 2.1 8.5 5.8 1.3 9.2 0.5 2.3 2 0 0 2 2 2 0 VEGF heparin-binding domain Atg14 PF10186.9 EKX52697.1 - 0.013 14.6 8.7 0.017 14.2 8.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FRG2 PF15315.6 EKX52697.1 - 1.2 9.3 8.3 0.067 13.4 1.0 2.2 1 1 1 2 2 2 0 Facioscapulohumeral muscular dystrophy candidate 2 HIP1_clath_bdg PF16515.5 EKX52697.1 - 3.5 8.3 22.0 5.2 7.7 10.0 2.7 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ATG16 PF08614.11 EKX52697.1 - 4 7.6 23.2 52 4.0 21.8 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CENP-H PF05837.12 EKX52697.1 - 5.4 7.5 19.0 2.9 8.3 14.7 2.4 1 1 2 3 3 3 0 Centromere protein H (CENP-H) HMMR_N PF15905.5 EKX52698.1 - 4.3e-05 23.2 3.1 4.8e-05 23.0 3.1 1.1 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal UPF0242 PF06785.11 EKX52698.1 - 0.00014 22.0 3.4 0.00015 21.9 3.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 EKX52698.1 - 0.00072 19.8 9.2 0.00092 19.5 9.2 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) HALZ PF02183.18 EKX52698.1 - 0.00088 19.4 1.0 0.00088 19.4 1.0 2.4 1 1 1 2 2 2 1 Homeobox associated leucine zipper bZIP_1 PF00170.21 EKX52698.1 - 0.00098 19.2 7.3 0.00098 19.2 7.3 2.4 1 1 2 3 3 3 1 bZIP transcription factor Spc7 PF08317.11 EKX52698.1 - 0.001 18.0 6.1 0.0012 17.8 6.1 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_13 PF13166.6 EKX52698.1 - 0.0011 17.7 4.1 0.0013 17.5 4.1 1.1 1 0 0 1 1 1 1 AAA domain DUF3450 PF11932.8 EKX52698.1 - 0.0014 17.9 3.9 0.0017 17.7 3.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Laminin_II PF06009.12 EKX52698.1 - 0.0016 18.4 1.6 0.0023 18.0 1.6 1.2 1 0 0 1 1 1 1 Laminin Domain II SOG2 PF10428.9 EKX52698.1 - 0.0018 17.6 0.4 0.0019 17.5 0.4 1.0 1 0 0 1 1 1 1 RAM signalling pathway protein YabA PF06156.13 EKX52698.1 - 0.002 18.8 6.4 0.0037 17.9 6.2 1.5 1 1 0 1 1 1 1 Initiation control protein YabA Fez1 PF06818.15 EKX52698.1 - 0.0033 17.9 7.9 0.0041 17.6 7.9 1.1 1 0 0 1 1 1 1 Fez1 DUF2968 PF11180.8 EKX52698.1 - 0.0037 16.9 4.8 0.0045 16.6 4.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) Atg14 PF10186.9 EKX52698.1 - 0.0037 16.4 6.5 0.0044 16.2 6.5 1.0 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4201 PF13870.6 EKX52698.1 - 0.0042 16.9 4.9 0.0052 16.5 4.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) Uso1_p115_C PF04871.13 EKX52698.1 - 0.0052 17.2 8.1 0.0077 16.6 8.1 1.3 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region DUF812 PF05667.11 EKX52698.1 - 0.006 15.5 3.0 0.007 15.3 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) CENP-H PF05837.12 EKX52698.1 - 0.0068 16.8 8.0 0.0092 16.4 8.0 1.2 1 0 0 1 1 1 1 Centromere protein H (CENP-H) DUF745 PF05335.13 EKX52698.1 - 0.0085 15.8 1.3 0.0098 15.6 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF745) DUF724 PF05266.14 EKX52698.1 - 0.014 15.2 5.0 0.018 14.9 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Phage_GPO PF05929.11 EKX52698.1 - 0.014 15.0 3.0 0.016 14.8 3.0 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase APG6_N PF17675.1 EKX52698.1 - 0.016 15.7 10.2 0.022 15.3 10.2 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region TMCO5 PF14992.6 EKX52698.1 - 0.017 14.7 5.9 0.022 14.4 5.9 1.2 1 0 0 1 1 1 0 TMCO5 family AAA_23 PF13476.6 EKX52698.1 - 0.024 15.1 2.7 0.026 15.0 2.7 1.1 1 0 0 1 1 1 0 AAA domain Cnn_1N PF07989.11 EKX52698.1 - 0.025 14.7 9.4 0.094 12.9 9.4 1.9 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 Prominin PF05478.11 EKX52698.1 - 0.025 12.5 0.9 0.028 12.4 0.9 1.0 1 0 0 1 1 1 0 Prominin Sec34 PF04136.15 EKX52698.1 - 0.032 14.1 3.2 0.04 13.8 3.2 1.2 1 0 0 1 1 1 0 Sec34-like family FapA PF03961.13 EKX52698.1 - 0.038 12.6 0.8 0.039 12.6 0.8 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A ADIP PF11559.8 EKX52698.1 - 0.05 13.7 8.9 0.07 13.2 8.9 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding GAS PF13851.6 EKX52698.1 - 0.051 12.9 8.1 0.062 12.7 8.1 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF2205 PF10224.9 EKX52698.1 - 0.058 13.4 5.9 0.1 12.6 5.3 1.8 1 1 0 1 1 1 0 Short coiled-coil protein SecA_DEAD PF07517.14 EKX52698.1 - 0.082 12.2 1.1 0.1 11.9 1.1 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain TSNAXIP1_N PF15739.5 EKX52698.1 - 0.091 13.2 5.3 0.067 13.6 3.4 1.6 1 1 0 1 1 1 0 Translin-associated factor X-interacting N-terminus GrpE PF01025.19 EKX52698.1 - 0.11 12.1 8.6 0.19 11.4 8.6 1.5 1 1 0 1 1 1 0 GrpE DUF1664 PF07889.12 EKX52698.1 - 0.12 12.4 3.1 0.24 11.5 3.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DivIC PF04977.15 EKX52698.1 - 0.13 12.0 7.0 0.25 11.2 6.6 1.8 1 1 0 1 1 1 0 Septum formation initiator HlyD_2 PF12700.7 EKX52698.1 - 0.15 10.8 1.9 0.17 10.6 1.9 1.1 1 0 0 1 1 1 0 HlyD family secretion protein ZapB PF06005.12 EKX52698.1 - 0.16 12.5 14.5 1.5 9.3 3.5 2.2 1 1 1 2 2 2 0 Cell division protein ZapB BLOC1_2 PF10046.9 EKX52698.1 - 0.18 12.1 5.3 0.41 11.0 5.4 1.6 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 EKX52698.1 - 0.2 11.9 0.6 0.31 11.3 0.6 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) KELK PF15796.5 EKX52698.1 - 0.23 11.9 10.9 0.33 11.4 10.9 1.2 1 0 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase BST2 PF16716.5 EKX52698.1 - 0.29 11.7 9.8 0.93 10.1 9.6 1.8 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 TMF_TATA_bd PF12325.8 EKX52698.1 - 0.37 11.0 12.0 0.46 10.7 9.7 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding FlaC_arch PF05377.11 EKX52698.1 - 0.37 11.2 4.9 1.3 9.5 4.4 2.0 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF641 PF04859.12 EKX52698.1 - 0.42 11.0 6.1 5.4 7.4 0.6 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) AAA_30 PF13604.6 EKX52698.1 - 0.46 10.2 3.1 0.96 9.1 0.2 2.0 1 1 1 2 2 2 0 AAA domain TMPIT PF07851.13 EKX52698.1 - 0.5 9.6 2.3 0.58 9.3 2.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.19 EKX52698.1 - 0.68 7.8 3.2 0.76 7.6 3.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0449 PF15136.6 EKX52698.1 - 1.5 9.4 8.0 6.4 7.3 0.6 2.2 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 Cep57_MT_bd PF06657.13 EKX52698.1 - 1.8 9.1 8.2 0.41 11.1 2.0 2.2 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 MctB PF11382.8 EKX52698.1 - 2.5 7.7 5.3 5.6 6.6 5.3 1.7 1 1 0 1 1 1 0 Copper transport outer membrane protein, MctB SlyX PF04102.12 EKX52698.1 - 2.7 8.7 8.7 13 6.5 2.5 2.3 1 1 1 2 2 2 0 SlyX DUF4404 PF14357.6 EKX52698.1 - 2.9 8.6 8.0 7.7 7.2 6.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) Spc24 PF08286.11 EKX52698.1 - 8.4 6.7 11.0 1.2e+02 3.0 11.0 2.1 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Maf PF02545.14 EKX52699.1 - 1.1e-26 93.7 0.0 1.2e-26 93.5 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein NUC205 PF08168.11 EKX52699.1 - 0.086 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 NUC205 domain Laminin_B PF00052.18 EKX52700.1 - 6.7e-10 39.0 0.0 2.3e-09 37.2 0.0 1.9 1 1 0 1 1 1 1 Laminin B (Domain IV) Zn_clus PF00172.18 EKX52702.1 - 4.2e-15 55.6 31.2 1.9e-07 31.1 11.7 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Vps39_2 PF10367.9 EKX52702.1 - 9.9 6.7 14.3 6.4 7.3 2.4 2.7 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 BRO1 PF03097.18 EKX52704.1 - 7.9e-31 107.2 1.5 1e-30 106.8 1.5 1.0 1 0 0 1 1 1 1 BRO1-like domain U-box PF04564.15 EKX52705.1 - 4.5e-21 74.8 0.8 9.9e-21 73.7 0.8 1.6 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX52705.1 - 1.6e-06 27.8 0.0 3.4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EKX52705.1 - 0.00042 20.3 0.0 0.00083 19.3 0.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Nop14 PF04147.12 EKX52705.1 - 0.0028 15.9 21.1 0.0033 15.7 21.1 1.1 1 0 0 1 1 1 1 Nop14-like family zf-NOSIP PF15906.5 EKX52705.1 - 0.0032 17.6 0.0 0.0066 16.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_2 PF13923.6 EKX52705.1 - 0.024 14.5 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX52705.1 - 0.12 12.7 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EKX52705.1 - 0.22 11.7 0.0 0.45 10.7 0.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING WDCP PF15390.6 EKX52705.1 - 1.8 6.9 15.0 2.1 6.6 15.0 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family LtuB PF17455.2 EKX52705.1 - 2.3 8.9 6.7 0.19 12.4 1.1 2.0 2 0 0 2 2 2 0 Late transcription unit B CHAT PF12770.7 EKX52706.1 - 1e-42 146.6 1.0 2e-42 145.6 1.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_MalT PF17874.1 EKX52706.1 - 8.8e-09 35.2 0.5 2.1e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 MalT-like TPR region TPR_12 PF13424.6 EKX52706.1 - 1e-08 35.4 12.3 0.0021 18.3 0.1 5.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX52706.1 - 2.1e-06 27.5 12.4 0.0076 16.4 0.0 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX52706.1 - 5.5e-06 26.1 18.2 0.0092 16.0 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX52706.1 - 6.8e-06 25.8 15.4 0.0011 18.7 0.0 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX52706.1 - 1.2e-05 24.9 13.5 0.13 12.2 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat RPN7 PF10602.9 EKX52706.1 - 0.00011 22.0 2.3 0.0004 20.2 0.5 2.2 2 0 0 2 2 2 1 26S proteasome subunit RPN7 Peptidase_C50 PF03568.17 EKX52706.1 - 0.0004 19.6 1.4 0.0026 16.9 1.4 2.3 1 1 0 1 1 1 1 Peptidase family C50 TPR_7 PF13176.6 EKX52706.1 - 0.00043 20.1 5.8 0.019 15.0 0.1 4.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX52706.1 - 0.0038 17.7 2.2 13 6.3 0.1 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EKX52706.1 - 0.011 16.4 0.7 5.4 7.8 0.3 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EKX52706.1 - 0.027 14.6 0.1 12 6.2 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EKX52706.1 - 0.078 12.7 3.0 0.23 11.2 0.0 2.8 3 0 0 3 3 3 0 TPR repeat TPR_14 PF13428.6 EKX52706.1 - 0.23 12.4 0.0 0.23 12.4 0.0 4.9 5 1 1 6 6 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX52706.1 - 0.31 11.8 1.0 25 5.8 0.0 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat LRR_6 PF13516.6 EKX52708.1 - 1.3e-14 52.9 6.0 1.4e-05 24.8 0.0 4.4 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.7 EKX52708.1 - 0.00018 21.8 1.6 0.041 14.3 0.1 2.5 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX52708.1 - 0.001 18.8 2.5 0.18 11.6 0.3 2.9 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 EKX52708.1 - 0.0034 17.7 0.0 9.1 7.3 0.0 3.5 3 0 0 3 3 3 1 Leucine Rich Repeat KorB PF08535.10 EKX52708.1 - 0.027 14.5 0.4 0.17 12.0 0.1 2.0 2 0 0 2 2 2 0 KorB domain DUF5593 PF18007.1 EKX52708.1 - 0.11 13.3 0.1 0.22 12.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5593) DUF240 PF03086.14 EKX52708.1 - 0.18 11.7 2.3 0.24 11.3 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF240) ATP-gua_Ptrans PF00217.19 EKX52709.1 - 1.7e-132 439.4 0.0 1.4e-64 217.5 0.0 3.0 3 0 0 3 3 3 2 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 EKX52709.1 - 2.9e-32 110.9 0.0 1.5e-15 57.3 0.0 2.4 2 0 0 2 2 2 2 ATP:guanido phosphotransferase, N-terminal domain AIRS_C PF02769.22 EKX52709.1 - 0.0035 17.5 5.8 0.85 9.7 0.4 2.7 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain Sec7_N PF12783.7 EKX52709.1 - 0.0065 16.4 0.0 5.9 6.8 0.0 2.6 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF3083 PF11281.8 EKX52709.1 - 0.089 12.1 0.1 8.9 5.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3083) Ribosomal_60s PF00428.19 EKX52709.1 - 0.45 11.1 12.0 1.5 9.5 4.7 2.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein RIIa PF02197.17 EKX52710.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit DUF5582 PF17819.1 EKX52710.1 - 0.02 15.3 0.7 0.032 14.7 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5582) Neuraminidase PF18413.1 EKX52710.1 - 0.098 12.3 0.0 0.2 11.3 0.0 1.6 1 1 0 1 1 1 0 Neuraminidase-like domain CIAPIN1 PF05093.13 EKX52711.1 - 3.1e-20 72.5 18.3 7.8e-16 58.4 4.7 2.4 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Glutaredoxin PF00462.24 EKX52711.1 - 1.3e-06 28.6 0.0 2.4e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Nucleotid_trans PF03407.16 EKX52712.1 - 4.6e-13 49.6 0.0 8e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase RGS-like PF09128.11 EKX52712.1 - 0.023 14.4 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Acetyltransf_9 PF13527.7 EKX52713.1 - 5.4e-11 42.7 0.0 1e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EKX52713.1 - 5.8e-05 23.4 0.0 0.00013 22.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EKX52713.1 - 0.0014 18.6 0.0 0.026 14.5 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EKX52713.1 - 0.0072 16.6 0.0 0.13 12.5 0.0 2.5 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Aldedh PF00171.22 EKX52714.1 - 2.2e-133 445.2 0.4 2.6e-133 444.9 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LPD30 PF18850.1 EKX52714.1 - 0.12 12.1 0.1 0.3 10.9 0.1 1.6 1 0 0 1 1 1 0 Large polyvalent protein associated domain 30 Mfa_like_2 PF15415.6 EKX52714.1 - 0.15 10.9 0.0 1.4 7.7 0.0 2.1 2 0 0 2 2 2 0 Fimbrillin-like RRM_1 PF00076.22 EKX52716.1 - 8.3e-15 54.4 0.0 9.8e-15 54.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 EKX52717.1 - 1.2e-10 41.1 0.0 1.4e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EKX52717.1 - 0.019 15.1 0.0 0.14 12.3 0.0 1.9 1 1 0 1 1 1 0 RNA recognition motif DUF4200 PF13863.6 EKX52718.1 - 0.00096 19.5 16.3 0.00096 19.5 16.3 10.2 2 2 6 9 9 9 2 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.12 EKX52718.1 - 0.0034 17.4 25.7 0.0034 17.4 25.7 9.7 2 2 6 9 9 9 1 TPR/MLP1/MLP2-like protein KASH_CCD PF14662.6 EKX52718.1 - 0.0037 17.1 29.8 0.0037 17.1 29.8 6.6 1 1 6 7 7 7 1 Coiled-coil region of CCDC155 or KASH DUF5320 PF17253.2 EKX52718.1 - 0.38 11.9 0.0 0.38 11.9 0.0 11.6 5 4 6 12 12 12 0 Family of unknown function (DUF5320) FlaC_arch PF05377.11 EKX52719.1 - 0.11 12.9 7.2 0.063 13.7 2.6 3.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) PDZ PF00595.24 EKX52720.1 - 7.1e-10 39.1 0.0 2.6e-09 37.3 0.0 2.0 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX52720.1 - 9.9e-08 31.7 0.2 2.9e-07 30.2 0.2 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX52720.1 - 3.7e-06 27.2 0.1 1.4e-05 25.3 0.1 2.1 1 0 0 1 1 1 1 PDZ domain CENP-Q PF13094.6 EKX52720.1 - 0.037 14.2 0.4 0.037 14.2 0.4 7.3 1 1 5 6 6 6 0 CENP-Q, a CENPA-CAD centromere complex subunit GRASP55_65 PF04495.14 EKX52720.1 - 0.11 12.8 0.1 0.36 11.1 0.0 1.8 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain DUF2703 PF10865.8 EKX52720.1 - 0.47 10.6 12.7 0.23 11.6 0.7 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF2703) DUF2935 PF11155.8 EKX52720.1 - 7.2 7.0 13.1 2.9 8.2 1.2 4.3 1 1 2 3 3 3 0 Domain of unknown function (DUF2935) DUF3682 PF12446.8 EKX52721.1 - 0.013 16.0 6.3 0.013 16.0 6.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) Furin-like_2 PF15913.5 EKX52721.1 - 0.027 14.6 0.8 0.083 13.1 0.8 1.8 1 0 0 1 1 1 0 Furin-like repeat, cysteine-rich LRR_8 PF13855.6 EKX52723.1 - 3.7e-29 100.3 26.7 2.3e-09 36.9 0.9 6.0 4 2 4 8 8 8 6 Leucine rich repeat LRR_4 PF12799.7 EKX52723.1 - 2.4e-19 69.1 12.9 2.6e-05 24.5 0.2 6.6 3 2 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX52723.1 - 1.3e-06 28.1 21.6 6.5 7.7 0.1 9.1 11 0 0 11 11 11 4 Leucine Rich Repeat LRR_6 PF13516.6 EKX52723.1 - 5.7e-05 22.8 15.3 2.9 8.2 0.1 7.3 8 0 0 8 8 8 3 Leucine Rich repeat CSTF_C PF14304.6 EKX52723.1 - 0.18 11.4 0.7 39 3.9 0.0 3.4 4 0 0 4 4 4 0 Transcription termination and cleavage factor C-terminal LRR_8 PF13855.6 EKX52724.1 - 6e-25 86.8 69.9 5.1e-09 35.8 11.8 4.4 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 EKX52724.1 - 2.8e-16 59.4 39.0 2e-05 24.8 2.7 5.6 4 2 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX52724.1 - 0.00021 20.9 2.0 0.00021 20.9 2.0 2.7 1 1 2 3 3 3 1 Leucine-rich repeat LRR_5 PF13306.6 EKX52724.1 - 0.0026 17.7 1.6 0.34 10.9 0.1 2.3 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EKX52724.1 - 0.0045 17.3 32.0 2.7 8.9 0.5 8.3 8 1 0 8 8 8 2 Leucine Rich Repeat Med24_N PF11277.8 EKX52724.1 - 0.064 11.3 0.1 0.082 11.0 0.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal DUF2322 PF10084.9 EKX52724.1 - 0.076 13.0 0.8 2.6 8.1 0.2 3.2 4 1 1 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2322) LRR_4 PF12799.7 EKX52725.1 - 3e-43 145.1 56.5 2.6e-05 24.5 2.7 12.2 9 3 3 12 12 12 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX52725.1 - 1.9e-38 130.1 59.1 2.6e-06 27.1 1.4 8.9 4 1 8 12 12 12 12 Leucine rich repeat LRR_1 PF00560.33 EKX52725.1 - 2.1e-07 30.5 44.9 1 10.1 0.1 15.6 16 2 0 16 16 16 2 Leucine Rich Repeat RsmF_methylt_CI PF17126.5 EKX52725.1 - 2.7e-05 24.1 3.5 4.2 7.5 0.0 6.8 5 3 1 6 6 6 2 RsmF rRNA methyltransferase first C-terminal domain CREPT PF16566.5 EKX52725.1 - 0.14 12.3 6.2 6.8 6.9 0.1 5.6 5 2 2 7 7 7 0 Cell-cycle alteration and expression-elevated protein in tumour Pkinase PF00069.25 EKX52726.1 - 1.3e-26 93.6 0.5 1.3e-26 93.6 0.5 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX52726.1 - 1.2e-15 57.5 2.4 4.8e-15 55.5 0.2 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase FHA PF00498.26 EKX52726.1 - 1.7e-11 44.3 0.0 4.2e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EKX52726.1 - 0.00017 21.8 0.2 0.0011 19.3 0.0 2.2 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase PF00069.25 EKX52727.1 - 7.1e-36 123.9 0.0 9.1e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX52727.1 - 2.4e-13 50.0 0.0 3.1e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX52727.1 - 0.00041 19.2 0.0 0.00055 18.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EKX52727.1 - 0.00065 19.1 0.0 0.0014 18.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.11 EKX52727.1 - 0.046 12.7 0.0 0.058 12.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HEAT_2 PF13646.6 EKX52729.1 - 6.9e-11 42.4 0.3 1.4e-09 38.2 0.1 2.8 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.22 EKX52729.1 - 9.1e-09 34.8 3.7 0.042 14.1 0.0 4.4 4 0 0 4 4 4 3 HEAT repeat Cnd1 PF12717.7 EKX52729.1 - 0.052 13.6 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Maf_N PF08383.11 EKX52729.1 - 0.097 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Maf N-terminal region HEAT_EZ PF13513.6 EKX52729.1 - 0.24 12.0 1.2 12 6.6 0.1 2.8 2 0 0 2 2 2 0 HEAT-like repeat Atg14 PF10186.9 EKX52729.1 - 1.4 7.9 7.3 0.058 12.5 0.5 1.9 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Mito_carr PF00153.27 EKX52730.1 - 2e-05 24.4 2.7 0.0035 17.2 0.1 3.5 3 1 0 3 3 3 2 Mitochondrial carrier protein TMEM65 PF10507.9 EKX52731.1 - 7.4e-47 157.8 2.8 8.5e-47 157.6 2.8 1.0 1 0 0 1 1 1 1 Transmembrane protein 65 Ribosomal_S30 PF04758.14 EKX52732.1 - 3.4e-26 91.2 8.3 7.3e-26 90.1 8.3 1.6 1 0 0 1 1 1 1 Ribosomal protein S30 ubiquitin PF00240.23 EKX52732.1 - 1.8e-07 30.8 0.0 3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family SET PF00856.28 EKX52734.1 - 0.13 12.6 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 SET domain NAPRTase PF04095.16 EKX52735.1 - 2.2e-41 142.1 0.0 2.9e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF5598 PF18127.1 EKX52735.1 - 9.8e-12 45.2 0.1 4e-11 43.2 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5598) PIP5K PF01504.18 EKX52736.1 - 7.9e-18 64.6 0.0 9e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase PP_kinase PF02503.17 EKX52736.1 - 0.076 12.6 0.0 0.085 12.4 0.0 1.1 1 0 0 1 1 1 0 Polyphosphate kinase middle domain Nebulin PF00880.18 EKX52736.1 - 0.22 11.5 0.0 0.36 10.8 0.0 1.3 1 0 0 1 1 1 0 Nebulin repeat Ribosomal_L27A PF00828.19 EKX52737.1 - 1.1e-31 110.2 0.9 1.6e-31 109.7 0.9 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A PH PF00169.29 EKX52738.1 - 1e-10 42.0 0.0 1.7e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EKX52738.1 - 0.045 14.2 0.4 0.25 11.8 0.4 2.2 1 1 0 1 1 1 0 Pleckstrin homology domain UDPGT PF00201.18 EKX52738.1 - 0.11 11.3 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.20 EKX52738.1 - 0.17 11.9 0.0 0.42 10.6 0.0 1.8 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Ank_5 PF13857.6 EKX52739.1 - 4.6e-12 45.9 2.1 7.9e-09 35.6 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX52739.1 - 5.8e-12 46.0 0.1 1.1e-11 45.2 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX52739.1 - 9.3e-11 42.0 0.1 2.4e-06 28.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX52739.1 - 7.2e-10 38.2 0.1 3.3e-05 24.0 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EKX52739.1 - 4.8e-08 33.1 0.2 4.3e-05 23.8 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeat CsbD PF05532.12 EKX52740.1 - 0.0012 18.7 36.1 0.37 10.7 2.4 5.8 5 0 0 5 5 5 4 CsbD-like PH PF00169.29 EKX52740.1 - 0.028 14.9 0.0 0.075 13.6 0.0 1.7 1 0 0 1 1 1 0 PH domain Adhesin_P1_N PF18652.1 EKX52740.1 - 0.03 14.3 23.0 3.7 7.6 0.7 5.3 4 0 0 4 4 4 0 Adhesin P1 N-terminal domain Dynein_attach_N PF15867.5 EKX52740.1 - 0.11 12.5 22.5 8.1 6.5 0.2 6.0 5 0 0 5 5 5 0 Dynein attachment factor N-terminus SapB_1 PF05184.15 EKX52740.1 - 1.2 9.2 3.5 0.57 10.3 0.2 2.3 2 0 0 2 2 2 0 Saposin-like type B, region 1 TRAF_BIRC3_bd PF16673.5 EKX52740.1 - 1.6 8.6 45.4 1.2 9.0 2.1 6.6 7 0 0 7 7 7 0 TNF receptor-associated factor BIRC3 binding domain UPRTase PF14681.6 EKX52742.1 - 2.2e-60 203.6 0.0 2.6e-60 203.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AMP-binding PF00501.28 EKX52743.1 - 1.5e-66 224.8 0.0 2.1e-66 224.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.24 EKX52743.1 - 8.1e-10 38.0 19.1 0.00031 20.3 1.3 7.4 7 0 0 7 7 7 2 Bacterial transferase hexapeptide (six repeats) AMP-binding_C PF13193.6 EKX52743.1 - 1.4e-09 38.8 4.2 3.3e-06 28.0 3.1 2.5 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain PP-binding PF00550.25 EKX52743.1 - 6.6e-09 36.0 0.0 1.9e-08 34.5 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site GH3 PF03321.13 EKX52743.1 - 0.02 13.8 0.0 0.059 12.2 0.0 1.6 2 0 0 2 2 2 0 GH3 auxin-responsive promoter WD40 PF00400.32 EKX52745.1 - 0.00014 22.5 3.0 10 7.2 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX52745.1 - 0.0013 19.0 0.0 0.13 12.6 0.0 3.4 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain GlgX_C PF18390.1 EKX52745.1 - 0.16 11.7 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Glycogen debranching enzyme C-terminal domain Tubulin PF00091.25 EKX52746.1 - 1.3e-66 224.6 0.0 1.9e-66 224.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EKX52746.1 - 2.3e-50 170.0 0.1 3.7e-50 169.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EKX52746.1 - 0.0017 18.1 0.0 0.0075 16.0 0.0 2.0 2 0 0 2 2 2 1 Tubulin domain Spermine_synth PF01564.17 EKX52747.1 - 0.00023 20.6 0.0 0.00041 19.8 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain CEL_III_C PF18054.1 EKX52747.1 - 0.18 11.8 1.0 0.37 10.9 1.0 1.6 1 0 0 1 1 1 0 CEL-III C-terminal RCC1 PF00415.18 EKX52748.1 - 6.8e-22 77.8 7.1 1.3e-09 38.5 0.7 3.4 3 1 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX52748.1 - 2.3e-16 59.1 9.6 7.9e-10 38.3 1.8 2.2 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat SPASM PF13186.6 EKX52748.1 - 0.014 15.9 1.0 1.8 9.2 0.1 2.2 2 0 0 2 2 2 0 Iron-sulfur cluster-binding domain DUF3641 PF12345.8 EKX52748.1 - 0.09 12.8 1.3 1.2 9.2 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3641) RCC1 PF00415.18 EKX52749.1 - 2.7e-23 82.3 8.4 3.2e-07 30.9 0.6 3.2 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX52749.1 - 4.4e-10 39.1 17.0 1.1e-07 31.4 0.3 4.6 4 1 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat Glutaredoxin PF00462.24 EKX52750.1 - 6.3e-19 68.0 0.0 1.1e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 EKX52750.1 - 0.089 13.2 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain SAP PF02037.27 EKX52751.1 - 1.3e-09 37.5 0.4 2.2e-09 36.8 0.4 1.4 1 0 0 1 1 1 1 SAP domain Rho_N PF07498.12 EKX52751.1 - 0.18 11.7 0.0 0.47 10.4 0.0 1.7 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain Exo_endo_phos PF03372.23 EKX52752.1 - 6.7e-08 32.3 0.1 1.7e-07 31.0 0.1 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TIR_2 PF13676.6 EKX52753.1 - 1.2e-12 48.5 0.1 3.1e-10 40.7 0.1 2.7 2 0 0 2 2 2 2 TIR domain BTK PF00779.19 EKX52753.1 - 2.2e-05 24.2 2.2 4.1e-05 23.3 2.2 1.5 1 0 0 1 1 1 1 BTK motif zf-Sec23_Sec24 PF04810.15 EKX52753.1 - 0.27 11.3 1.5 0.97 9.5 1.5 2.0 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger Zn_ribbon_recom PF13408.6 EKX52753.1 - 4.2 8.0 6.5 8.2 7.0 6.5 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain FAM76 PF16046.5 EKX52755.1 - 4.2 6.6 9.0 6.2 6.1 9.0 1.1 1 0 0 1 1 1 0 FAM76 protein Asp PF00026.23 EKX52756.1 - 1.8e-18 67.1 0.0 5.5e-12 45.7 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 EKX52756.1 - 0.00014 21.7 0.0 0.016 15.0 0.0 2.6 2 1 1 3 3 3 2 Xylanase inhibitor C-terminal TAXi_N PF14543.6 EKX52756.1 - 0.015 15.6 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal FKBP_C PF00254.28 EKX52757.1 - 9.8e-29 99.5 0.0 1.2e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase bMG5 PF17972.1 EKX52757.1 - 0.055 13.8 0.0 0.084 13.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG5 domain Mis12 PF05859.12 EKX52758.1 - 8.7e-26 90.6 0.1 2.1e-25 89.4 0.1 1.6 1 0 0 1 1 1 1 Mis12 protein DUF3450 PF11932.8 EKX52758.1 - 0.17 11.2 3.7 1.5 8.1 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 EKX52758.1 - 2.2 8.8 7.8 3.3 8.2 7.2 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region MORN PF02493.20 EKX52759.1 - 2e-48 159.4 53.8 2e-07 30.5 3.0 9.4 10 0 0 10 10 10 9 MORN repeat DUF3048_C PF17479.2 EKX52759.1 - 0.0027 18.1 7.7 0.82 10.1 0.6 3.7 1 1 2 4 4 4 3 Protein of unknown function (DUF3048) C-terminal domain Ank_2 PF12796.7 EKX52761.1 - 9.9e-35 119.0 0.7 0.00087 19.8 0.0 10.2 5 4 3 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX52761.1 - 2.8e-26 91.5 9.6 0.019 15.5 0.1 10.7 9 1 1 10 10 10 8 Ankyrin repeats (many copies) C2 PF00168.30 EKX52761.1 - 1.7e-15 57.1 0.0 3.5e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain Ank_5 PF13857.6 EKX52761.1 - 8.8e-15 54.6 10.3 0.00077 19.7 0.0 10.1 12 1 1 13 13 13 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX52761.1 - 2.9e-12 45.6 13.8 0.54 11.0 0.0 12.2 14 0 0 14 14 14 2 Ankyrin repeat Ank PF00023.30 EKX52761.1 - 6.8e-10 38.9 19.5 4.1 8.0 0.0 11.1 12 0 0 12 12 12 4 Ankyrin repeat Alpha-amylase PF00128.24 EKX52762.1 - 3.2e-59 201.2 0.0 4.7e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 EKX52762.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain Alpha-amylase_C PF02806.18 EKX52762.1 - 0.12 12.8 0.0 0.3 11.6 0.0 1.7 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain Transket_pyr PF02779.24 EKX52763.1 - 2.4e-46 157.6 0.0 3.5e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EKX52763.1 - 6.8e-46 155.2 0.2 1.5e-45 154.1 0.2 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 EKX52763.1 - 0.0027 18.0 0.1 0.016 15.5 0.1 2.1 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II Acetyltransf_1 PF00583.25 EKX52765.1 - 6.8e-15 55.3 0.1 1e-14 54.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EKX52765.1 - 1.4e-14 54.1 0.1 1.9e-14 53.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EKX52765.1 - 3.6e-10 40.1 0.2 5.7e-10 39.5 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EKX52765.1 - 6.9e-10 38.8 0.0 1.2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EKX52765.1 - 0.035 14.2 0.1 0.065 13.3 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-CCHC PF00098.23 EKX52766.1 - 5.5e-05 23.1 1.2 9.6e-05 22.3 1.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 EKX52766.1 - 0.009 15.7 0.4 0.018 14.8 0.4 1.4 1 0 0 1 1 1 1 C2H2 zinc-finger Cdc6_C PF09079.11 EKX52770.1 - 0.11 12.5 0.0 4.2 7.4 0.0 2.9 3 0 0 3 3 3 0 CDC6, C terminal winged helix domain Suppressor_APC PF11414.8 EKX52770.1 - 0.41 10.7 3.4 1.1 9.4 0.1 2.7 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein Sigma70_r4_2 PF08281.12 EKX52772.1 - 0.13 12.0 0.2 16 5.2 0.0 3.3 3 0 0 3 3 3 0 Sigma-70, region 4 zf-C4 PF00105.18 EKX52772.1 - 0.29 11.6 1.0 0.69 10.4 1.0 1.6 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) NPL4 PF05021.15 EKX52773.1 - 1.4e-91 307.0 0.0 2e-91 306.6 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 EKX52773.1 - 6.3e-25 88.0 0.0 1.5e-24 86.8 0.0 1.6 2 0 0 2 2 2 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 EKX52773.1 - 1.5e-10 41.4 0.0 3.9e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 UBA PF00627.31 EKX52773.1 - 0.00069 19.5 0.8 0.0018 18.1 0.8 1.8 1 0 0 1 1 1 1 UBA/TS-N domain AAA PF00004.29 EKX52774.1 - 7.2e-39 133.2 0.0 1.7e-16 60.8 0.0 3.4 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EKX52774.1 - 2.8e-12 46.3 0.1 1.8e-06 27.6 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_22 PF13401.6 EKX52774.1 - 4.2e-05 23.8 0.0 0.22 11.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EKX52774.1 - 8.7e-05 23.0 0.1 0.0092 16.4 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 EKX52774.1 - 0.00014 21.2 0.0 0.00028 20.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EKX52774.1 - 0.0015 18.3 0.0 0.003 17.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 EKX52774.1 - 0.004 16.9 0.0 0.037 13.8 0.0 2.3 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 EKX52774.1 - 0.0062 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EKX52774.1 - 0.012 15.7 0.0 0.037 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EKX52774.1 - 0.017 15.1 0.0 0.14 12.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 EKX52774.1 - 0.038 13.3 0.0 0.077 12.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 EKX52774.1 - 0.064 13.6 0.0 0.34 11.3 0.0 2.2 3 0 0 3 3 2 0 RNA helicase Mg_chelatase PF01078.21 EKX52774.1 - 0.082 12.3 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 EKX52774.1 - 0.084 13.4 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 EKX52774.1 - 0.093 13.3 0.0 0.23 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EKX52774.1 - 0.14 12.0 0.0 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 NACHT domain tRNA-synt_1b PF00579.25 EKX52775.1 - 1.3e-74 251.2 0.0 1.9e-74 250.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 EKX52775.1 - 4.4e-10 39.1 0.0 9.9e-10 38.0 0.0 1.6 1 0 0 1 1 1 1 S4 domain DUF2789 PF10982.8 EKX52775.1 - 0.055 13.6 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2789) tRNA-synt_1b PF00579.25 EKX52776.1 - 9.4e-75 251.6 0.0 1.3e-74 251.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 EKX52776.1 - 4e-10 39.2 0.0 8.4e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 S4 domain DUF2789 PF10982.8 EKX52776.1 - 0.044 13.9 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2789) RVT_1 PF00078.27 EKX52777.1 - 1.8e-08 34.2 0.1 3.4e-08 33.3 0.1 1.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CK2S PF15011.6 EKX52778.1 - 0.06 13.2 0.0 0.069 13.0 0.0 1.1 1 0 0 1 1 1 0 Casein Kinase 2 substrate Urb2 PF10441.9 EKX52779.1 - 0.016 15.2 0.1 0.052 13.5 0.1 2.0 1 1 0 1 1 1 0 Urb2/Npa2 family Multi_Drug_Res PF00893.19 EKX52779.1 - 0.071 13.8 0.0 0.18 12.5 0.0 1.7 1 0 0 1 1 1 0 Small Multidrug Resistance protein SLATT_fungal PF18142.1 EKX52779.1 - 0.075 13.0 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain TSA PF03249.13 EKX52780.1 - 0.7 8.6 2.0 0.89 8.3 2.0 1.1 1 0 0 1 1 1 0 Type specific antigen Syntaxin-18_N PF10496.9 EKX52780.1 - 1.4 9.3 6.0 15 5.9 6.0 2.3 1 1 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus DUF4508 PF14969.6 EKX52781.1 - 0.048 13.9 0.4 0.086 13.1 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) CUB PF00431.20 EKX52782.1 - 7.3e-07 29.5 0.0 1.2e-05 25.5 0.0 3.0 2 0 0 2 2 2 1 CUB domain Lectin_leg-like PF03388.13 EKX52782.1 - 0.0003 20.2 2.9 0.00059 19.3 2.9 1.4 1 0 0 1 1 1 1 Legume-like lectin family MbtH PF03621.13 EKX52782.1 - 0.0013 18.2 6.8 3.1 7.3 0.1 6.4 8 0 0 8 8 8 1 MbtH-like protein NPCBM_assoc PF10633.9 EKX52782.1 - 0.036 14.3 7.2 40 4.6 0.0 6.2 7 0 0 7 7 7 0 NPCBM-associated, NEW3 domain of alpha-galactosidase GBP_PSP PF02425.15 EKX52782.1 - 0.65 9.7 10.3 24 4.7 0.1 5.3 4 0 0 4 4 4 0 Paralytic/GBP/PSP peptide PDZ PF00595.24 EKX52785.1 - 1.6e-08 34.8 0.3 2.7e-08 34.1 0.3 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX52785.1 - 7.5e-07 28.9 0.1 1.2e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX52785.1 - 1.8e-05 25.0 0.0 3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 EKX52785.1 - 0.053 13.9 0.0 0.062 13.6 0.0 1.1 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain ADK PF00406.22 EKX52786.1 - 1.5e-42 145.3 0.1 1.7e-42 145.1 0.1 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EKX52786.1 - 1.5e-33 116.1 0.2 1.7e-33 115.9 0.2 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EKX52786.1 - 1.6e-11 44.9 0.1 2.1e-11 44.5 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EKX52786.1 - 2.6e-07 30.9 0.0 3.3e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EKX52786.1 - 0.0011 18.7 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain dNK PF01712.19 EKX52786.1 - 0.0021 18.0 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 Deoxynucleoside kinase Zeta_toxin PF06414.12 EKX52786.1 - 0.0035 16.7 0.0 0.0043 16.3 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin Ploopntkinase3 PF18751.1 EKX52786.1 - 0.005 16.8 0.0 0.0058 16.6 0.0 1.4 1 1 0 1 1 1 1 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 EKX52786.1 - 0.095 12.9 0.0 0.31 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain SET PF00856.28 EKX52787.1 - 6.5e-11 42.9 0.0 7.1e-09 36.3 0.0 2.0 1 1 0 1 1 1 1 SET domain RRM_1 PF00076.22 EKX52788.1 - 1.6e-19 69.5 0.0 1.9e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EKX52788.1 - 0.0028 17.7 0.0 0.0035 17.4 0.0 1.1 1 0 0 1 1 1 1 RNA binding motif Limkain-b1 PF11608.8 EKX52788.1 - 0.16 12.1 0.0 0.18 11.9 0.0 1.4 1 1 0 1 1 1 0 Limkain b1 Methyltransf_21 PF05050.12 EKX52789.1 - 3.6e-09 36.9 0.0 1e-08 35.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase FkbM domain ATP-synt_ab PF00006.25 EKX52790.1 - 2.1e-62 210.6 0.0 3.3e-62 209.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EKX52790.1 - 5e-23 81.4 1.1 1.1e-22 80.3 1.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RsgA_GTPase PF03193.16 EKX52790.1 - 0.0018 18.2 0.1 0.0041 17.0 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase NB-ARC PF00931.22 EKX52790.1 - 0.0082 15.4 0.4 0.037 13.2 0.1 1.9 2 0 0 2 2 2 1 NB-ARC domain ATPase_2 PF01637.18 EKX52790.1 - 0.051 13.5 0.0 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EKX52790.1 - 0.075 13.4 0.7 0.27 11.6 0.2 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EKX52790.1 - 0.075 13.5 0.0 0.91 10.0 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EKX52790.1 - 0.1 12.0 0.9 0.32 10.3 0.4 2.0 2 0 0 2 2 2 0 KaiC AAA_16 PF13191.6 EKX52790.1 - 0.11 12.8 0.0 0.36 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain Ank_2 PF12796.7 EKX52793.1 - 1.9e-09 38.0 0.0 0.00048 20.7 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX52793.1 - 1.6e-06 28.2 0.0 1.9 8.9 0.0 4.8 4 2 1 5 5 5 2 Ankyrin repeats (many copies) MMR_HSR1 PF01926.23 EKX52793.1 - 6.2e-05 23.0 0.2 0.0003 20.8 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase Ank PF00023.30 EKX52793.1 - 7e-05 23.1 0.0 11 6.7 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 EKX52793.1 - 8.8e-05 22.6 0.1 38 5.3 0.0 6.0 6 0 0 6 6 6 0 Ankyrin repeat AAA_16 PF13191.6 EKX52793.1 - 0.02 15.3 0.0 0.14 12.5 0.0 2.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EKX52793.1 - 0.027 14.7 0.1 1.3 9.3 0.0 3.2 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EKX52793.1 - 0.031 14.2 0.2 0.21 11.5 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase NIR_SIR_ferr PF03460.17 EKX52793.1 - 0.14 12.1 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 Nitrite/Sulfite reductase ferredoxin-like half domain Ead_Ea22 PF13935.6 EKX52793.1 - 1.2 9.7 9.0 1.1 9.9 5.3 2.8 2 1 1 3 3 3 0 Ead/Ea22-like protein CMAS PF02353.20 EKX52795.1 - 7.1e-27 94.4 0.0 1.7e-26 93.2 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EKX52795.1 - 2e-15 57.3 0.0 3.3e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX52795.1 - 8e-15 55.3 0.0 1.7e-14 54.2 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX52795.1 - 1.3e-12 47.8 0.0 1.7e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX52795.1 - 2.7e-12 46.9 0.0 4e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX52795.1 - 2.8e-12 47.2 0.0 4.5e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EKX52795.1 - 5e-07 29.4 0.0 8e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EKX52795.1 - 6.6e-05 22.4 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase TehB PF03848.14 EKX52795.1 - 6.9e-05 22.3 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB DUF938 PF06080.12 EKX52795.1 - 0.00093 19.0 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) tRNA_U5-meth_tr PF05958.11 EKX52795.1 - 0.005 15.9 0.0 0.0086 15.1 0.0 1.3 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltr_RsmB-F PF01189.17 EKX52795.1 - 0.0073 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F RrnaAD PF00398.20 EKX52795.1 - 0.018 14.1 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.19 EKX52795.1 - 0.024 14.4 0.0 0.044 13.5 0.0 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_17 PF12692.7 EKX52795.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase RepA1_leader PF08048.12 EKX52796.1 - 0.082 13.2 0.6 0.14 12.4 0.6 1.4 1 0 0 1 1 1 0 Tap RepA1 leader peptide DUF3246 PF11596.8 EKX52797.1 - 0.71 9.3 5.3 1.4 8.3 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Antifungal_prot PF11402.8 EKX52798.1 - 0.07 13.4 1.1 2.1 8.6 0.1 2.5 2 0 0 2 2 2 0 Antifungal protein EF-hand_8 PF13833.6 EKX52798.1 - 0.09 12.6 0.1 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair Ephrin_rec_like PF07699.13 EKX52799.1 - 0.49 10.2 12.0 11 5.8 11.5 2.5 1 1 0 1 1 1 0 Putative ephrin-receptor like FCH PF00611.23 EKX52800.1 - 2.2e-05 24.7 11.0 7.7e-05 22.9 8.5 3.0 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Vps5 PF09325.10 EKX52800.1 - 0.03 13.9 10.6 0.069 12.7 0.1 2.4 2 1 0 2 2 2 0 Vps5 C terminal like DUF4047 PF13256.6 EKX52800.1 - 0.04 14.1 3.1 1.9 8.7 0.0 3.0 1 1 1 3 3 3 0 Domain of unknown function (DUF4047) HCMV_UL139 PF12507.8 EKX52800.1 - 0.084 13.3 4.7 0.085 13.2 2.5 2.3 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein DUF1759 PF03564.15 EKX52800.1 - 0.19 11.7 2.3 0.83 9.6 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) DUF1043 PF06295.12 EKX52800.1 - 3.4 7.7 8.3 6.6 6.8 5.6 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1043) SlyX PF04102.12 EKX52801.1 - 0.1 13.2 16.7 0.2 12.3 6.3 3.2 2 2 0 2 2 2 0 SlyX Peptidase_S66 PF02016.15 EKX52801.1 - 0.17 12.0 2.1 0.19 11.8 0.1 2.0 2 1 0 2 2 2 0 LD-carboxypeptidase N-terminal domain FAM76 PF16046.5 EKX52801.1 - 2 7.7 12.9 3.7 6.8 12.9 1.4 1 0 0 1 1 1 0 FAM76 protein DUF5320 PF17253.2 EKX52801.1 - 5.8 8.0 10.0 8 7.6 0.0 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5320) DUF724 PF05266.14 EKX52801.1 - 7.5 6.3 21.5 1.1 9.1 11.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) CTP_transf_3 PF02348.19 EKX52802.1 - 2.4e-31 109.4 0.0 2.6e-31 109.3 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 EKX52802.1 - 1.3e-09 38.6 0.0 1.7e-09 38.3 0.0 1.0 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 EKX52802.1 - 0.0055 16.5 0.0 0.0057 16.4 0.0 1.0 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Methyltransf_12 PF08242.12 EKX52803.1 - 2.1e-05 25.2 0.0 7.3e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX52803.1 - 6.8e-05 23.5 0.1 0.003 18.2 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX52803.1 - 9.2e-05 22.3 0.1 0.00051 19.9 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX52803.1 - 0.0014 19.2 0.5 0.005 17.5 0.5 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX52803.1 - 0.0035 17.2 0.0 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RRM_1 PF00076.22 EKX52804.1 - 8.1e-17 60.8 0.1 9.1e-17 60.6 0.1 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EKX52804.1 - 0.076 12.9 0.0 0.18 11.7 0.0 1.6 1 1 0 1 1 1 0 Occluded RNA-recognition motif DNA_pol_A PF00476.20 EKX52806.1 - 1.8e-106 356.3 0.0 2.1e-106 356.1 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase family A TSKS PF15358.6 EKX52806.1 - 0.054 11.9 0.0 0.099 11.0 0.0 1.4 1 0 0 1 1 1 0 Testis-specific serine kinase substrate HTH_20 PF12840.7 EKX52806.1 - 0.17 12.0 0.1 0.94 9.6 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain ABC_tran_CTD PF16326.5 EKX52807.1 - 0.027 14.7 1.6 0.056 13.7 1.6 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain RE_Bsp6I PF09504.10 EKX52809.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Bsp6I restriction endonuclease HTH_Tnp_Tc5 PF03221.16 EKX52809.1 - 0.12 12.4 1.0 6.7 6.8 0.0 3.0 3 1 1 4 4 4 0 Tc5 transposase DNA-binding domain SDA1 PF05285.12 EKX52810.1 - 1.2e-07 31.5 31.7 1.3e-07 31.3 31.7 1.1 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 EKX52810.1 - 0.023 14.0 35.6 0.03 13.7 35.6 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 EKX52810.1 - 0.12 10.6 48.8 0.14 10.3 48.8 1.0 1 0 0 1 1 1 0 Nop14-like family Acyltransferase PF01553.21 EKX52812.1 - 1.6e-26 92.5 0.1 2.6e-26 91.8 0.1 1.3 1 0 0 1 1 1 1 Acyltransferase NIPSNAP PF07978.13 EKX52813.1 - 9.6e-11 41.8 0.0 2.4e-10 40.6 0.0 1.6 1 1 0 1 1 1 1 NIPSNAP HEAT PF02985.22 EKX52815.1 - 3.6e-18 64.1 23.7 0.00024 21.1 0.0 8.7 10 0 0 10 10 8 4 HEAT repeat HEAT_2 PF13646.6 EKX52815.1 - 7.9e-18 64.6 17.5 2.3e-07 31.1 0.0 6.8 6 2 1 7 7 6 3 HEAT repeats Cnd1 PF12717.7 EKX52815.1 - 3.7e-09 36.8 0.1 0.0029 17.6 0.1 4.5 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EKX52815.1 - 3.8e-09 36.9 12.3 0.0056 17.2 0.0 6.9 5 1 0 5 5 5 2 HEAT-like repeat BIR PF00653.21 EKX52815.1 - 8.1e-08 32.8 1.8 4.6e-07 30.4 1.8 2.3 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain Adaptin_N PF01602.20 EKX52815.1 - 1.1e-06 27.5 0.1 0.0016 17.1 0.1 2.7 3 0 0 3 3 3 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 EKX52815.1 - 0.0033 18.0 0.0 0.21 12.2 0.0 3.8 6 0 0 6 6 4 1 Vacuolar 14 Fab1-binding region RICTOR_V PF14668.6 EKX52815.1 - 0.0059 16.8 0.0 12 6.2 0.0 4.3 5 0 0 5 5 4 0 Rapamycin-insensitive companion of mTOR, domain 5 DUF4042 PF13251.6 EKX52815.1 - 0.012 15.3 0.8 53 3.5 0.0 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) CLASP_N PF12348.8 EKX52815.1 - 0.016 14.7 0.3 0.61 9.6 0.3 2.5 2 0 0 2 2 2 0 CLASP N terminal PA PF02225.22 EKX52815.1 - 0.018 15.1 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 PA domain Arm PF00514.23 EKX52815.1 - 0.033 14.2 10.3 0.2 11.8 0.0 5.5 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Aldo_ket_red PF00248.21 EKX52815.1 - 0.065 12.4 0.1 0.9 8.7 0.0 2.3 2 0 0 2 2 2 0 Aldo/keto reductase family Peptidase_S49_N PF08496.10 EKX52815.1 - 0.067 13.3 0.2 0.25 11.4 0.2 2.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal C2 PF00168.30 EKX52815.1 - 0.07 13.4 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 C2 domain RTP1_C1 PF10363.9 EKX52815.1 - 0.11 12.7 0.0 3.4 7.9 0.0 3.1 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Amidohydro_1 PF01979.20 EKX52816.1 - 2.5e-12 46.8 0.1 4.2e-09 36.2 0.3 3.1 2 1 0 2 2 2 2 Amidohydrolase family EF-hand_6 PF13405.6 EKX52817.1 - 1.4e-09 37.1 0.5 4.1e-05 23.2 0.1 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EKX52817.1 - 8.5e-09 34.3 2.5 6e-05 22.3 0.2 3.3 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 EKX52817.1 - 1.1e-06 27.9 0.3 7.6e-05 22.0 0.1 2.7 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EKX52817.1 - 5.4e-06 26.8 3.7 0.00042 20.7 0.5 2.7 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 EKX52817.1 - 1.7e-05 24.6 2.6 0.00059 19.6 0.1 3.5 2 1 1 3 3 3 2 EF-hand domain pair EVI2A PF05399.11 EKX52817.1 - 0.11 12.1 14.2 1.3 8.6 11.3 2.2 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) Vps16_N PF04841.13 EKX52818.1 - 4.7e-84 282.5 0.0 7.3e-84 281.9 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 EKX52818.1 - 4.3e-56 190.3 4.1 5.8e-56 189.9 4.1 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 EKX52818.1 - 0.13 12.6 0.0 1.8 8.9 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L14e PF01929.17 EKX52819.1 - 4.5e-28 97.6 3.5 6.5e-28 97.0 3.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 REV PF00424.18 EKX52819.1 - 0.04 13.9 0.0 0.075 13.1 0.0 1.4 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) VASt PF16016.5 EKX52820.1 - 6.1e-21 75.4 1.6 1.1e-20 74.5 1.6 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EKX52820.1 - 1e-17 64.0 0.1 6.3e-17 61.5 0.0 2.2 2 0 0 2 2 2 1 GRAM domain Ammonium_transp PF00909.21 EKX52820.1 - 2.2e-11 43.1 0.4 3.3e-11 42.5 0.4 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family TACC_C PF05010.14 EKX52820.1 - 0.061 13.1 1.3 0.21 11.3 1.3 1.9 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal BRE1 PF08647.11 EKX52820.1 - 0.31 11.2 6.1 0.19 11.9 1.8 2.8 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase PCI PF01399.27 EKX52821.1 - 1.8e-09 38.0 0.1 1.8e-09 38.0 0.1 3.4 3 0 0 3 3 3 1 PCI domain NGP1NT PF08153.12 EKX52822.1 - 1.9e-40 138.0 0.3 5.5e-40 136.5 0.3 1.8 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 EKX52822.1 - 1.9e-14 53.7 0.1 3e-12 46.6 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EKX52822.1 - 0.001 19.0 0.0 0.0035 17.3 0.0 2.0 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 EKX52822.1 - 0.0079 15.7 0.2 0.023 14.2 0.1 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 EKX52822.1 - 0.008 15.7 0.0 4.7 6.6 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Calcipressin PF04847.12 EKX52822.1 - 0.065 13.0 4.5 0.21 11.3 4.5 1.9 1 0 0 1 1 1 0 Calcipressin GTP_EFTU PF00009.27 EKX52822.1 - 0.47 10.0 0.0 0.47 10.0 0.0 3.3 3 1 1 5 5 5 0 Elongation factor Tu GTP binding domain CAP_N PF01213.19 EKX52823.1 - 3.4 7.1 5.9 5 6.5 5.9 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Vps52 PF04129.12 EKX52826.1 - 2.5e-98 330.0 7.5 5.9e-85 285.9 2.8 2.0 2 0 0 2 2 2 2 Vps52 / Sac2 family Sec3_C PF09763.9 EKX52826.1 - 1.8e-15 56.4 9.5 6.7e-08 31.4 0.0 2.3 2 0 0 2 2 2 2 Exocyst complex component Sec3 Spc7 PF08317.11 EKX52826.1 - 0.022 13.6 5.0 0.49 9.2 4.9 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein COG5 PF10392.9 EKX52826.1 - 0.042 14.0 3.5 0.074 13.2 1.5 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 COG2 PF06148.11 EKX52826.1 - 0.19 11.8 4.9 0.21 11.7 3.2 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 YlbD_coat PF14071.6 EKX52826.1 - 0.21 11.9 2.5 1.5 9.1 0.2 3.0 2 1 1 3 3 3 0 Putative coat protein 5_nucleotid_C PF02872.18 EKX52827.1 - 2.4e-12 47.4 0.0 6.5e-12 45.9 0.0 1.7 1 1 0 1 1 1 1 5'-nucleotidase, C-terminal domain EF-hand_7 PF13499.6 EKX52827.1 - 2.1e-07 31.3 0.1 6.1e-07 29.8 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair Metallophos PF00149.28 EKX52827.1 - 5.1e-07 30.4 0.0 1.2e-06 29.2 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_8 PF13833.6 EKX52827.1 - 1.6e-06 27.8 0.4 6.1e-06 26.0 0.2 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX52827.1 - 3.1e-06 26.4 0.5 0.0063 16.0 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 EKX52827.1 - 4.2e-06 26.0 1.1 0.015 14.8 0.1 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EKX52827.1 - 0.00088 19.0 0.1 0.05 13.6 0.1 3.1 3 0 0 3 3 3 1 EF-hand domain TPMT PF05724.11 EKX52828.1 - 2e-29 102.9 0.0 2.5e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 EKX52828.1 - 1.3e-10 41.9 0.0 1.7e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX52828.1 - 1.4e-09 38.5 0.0 1.9e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX52828.1 - 4.6e-09 36.3 0.0 5.4e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX52828.1 - 4e-08 33.3 0.0 5.3e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX52828.1 - 1.3e-06 29.1 0.0 2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain N2227 PF07942.12 EKX52828.1 - 0.05 12.8 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein Galactosyl_T PF01762.21 EKX52828.1 - 0.13 12.0 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Galactosyltransferase Pkinase_Tyr PF07714.17 EKX52830.1 - 1.6e-49 168.5 0.0 1.8e-49 168.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX52830.1 - 4.8e-46 157.2 0.0 6.2e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 EKX52830.1 - 6.7e-05 22.0 0.1 0.00021 20.3 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EKX52830.1 - 0.00049 19.0 0.0 0.00073 18.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EKX52830.1 - 0.013 14.8 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EKX52830.1 - 0.014 14.8 0.1 0.02 14.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EKX52830.1 - 0.038 13.1 0.1 0.055 12.5 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 EKX52830.1 - 0.085 12.8 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABC_membrane_2 PF06472.15 EKX52830.1 - 0.11 11.8 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 2-Hacid_dh_C PF02826.19 EKX52831.1 - 5.5e-45 152.9 0.0 7.6e-45 152.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EKX52831.1 - 6.8e-19 67.9 0.1 7.7e-19 67.7 0.1 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EKX52831.1 - 0.00022 21.4 0.1 0.00047 20.4 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EKX52831.1 - 0.0076 16.8 0.7 0.095 13.3 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Aminotran_5 PF00266.19 EKX52832.1 - 0.0016 17.5 0.0 0.0027 16.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V NDK PF00334.19 EKX52833.1 - 3.7e-45 153.3 0.0 4.6e-45 153.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase BTK PF00779.19 EKX52834.1 - 0.0012 18.6 1.2 0.0012 18.6 1.2 6.5 7 0 0 7 7 7 2 BTK motif PH PF00169.29 EKX52836.1 - 1.4e-05 25.5 0.1 2.5e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EKX52836.1 - 0.0083 16.4 0.0 0.019 15.3 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 EKX52836.1 - 0.031 14.7 0.0 0.12 12.8 0.0 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain zf-RING_2 PF13639.6 EKX52837.1 - 3.5e-12 46.5 12.0 9.3e-12 45.1 12.0 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX52837.1 - 7.8e-08 32.0 12.6 7.8e-08 32.0 12.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX52837.1 - 8.1e-08 32.4 11.4 2.1e-07 31.1 11.4 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EKX52837.1 - 8.3e-08 31.8 3.0 2.9e-07 30.1 3.0 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EKX52837.1 - 6.1e-06 26.0 8.3 6.1e-06 26.0 8.3 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EKX52837.1 - 1.7e-05 24.7 4.3 5.5e-05 23.1 4.3 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EKX52837.1 - 7.4e-05 22.7 5.1 7.4e-05 22.7 5.1 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EKX52837.1 - 0.00061 19.6 11.4 0.0014 18.5 11.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EKX52837.1 - 0.002 17.7 10.0 0.0047 16.5 10.0 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 EKX52837.1 - 0.062 13.1 7.7 0.15 11.9 7.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Enkurin PF13864.6 EKX52837.1 - 0.094 13.2 1.7 0.19 12.2 0.8 1.9 1 1 1 2 2 2 0 Calmodulin-binding Ada3 PF10198.9 EKX52837.1 - 0.099 12.8 0.1 0.25 11.5 0.1 1.6 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 zinc_ribbon_16 PF17034.5 EKX52837.1 - 0.18 12.1 8.5 0.11 12.7 6.1 1.9 1 1 0 1 1 1 0 Zinc-ribbon like family zf-RING-like PF08746.11 EKX52837.1 - 0.18 12.1 5.3 0.44 10.9 5.3 1.6 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 EKX52837.1 - 0.2 11.8 10.6 0.6 10.3 10.6 1.9 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 EKX52837.1 - 2.7 8.2 10.8 11 6.3 10.8 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_5 PF14634.6 EKX52837.1 - 8.4 6.4 21.1 0.48 10.4 14.2 2.4 2 1 1 3 3 3 0 zinc-RING finger domain PDZ PF00595.24 EKX52838.1 - 8.5e-09 35.7 0.1 2.1e-08 34.4 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX52838.1 - 4.2e-07 29.7 0.1 1.1e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX52838.1 - 1e-05 25.7 0.1 1e-05 25.7 0.1 2.5 3 0 0 3 3 3 1 PDZ domain TIG PF01833.24 EKX52839.1 - 7.9e-08 32.3 0.8 8.6e-08 32.2 0.8 1.0 1 0 0 1 1 1 1 IPT/TIG domain TIG_plexin PF17960.1 EKX52839.1 - 0.064 13.3 0.0 0.064 13.3 0.0 1.1 1 0 0 1 1 1 0 TIG domain EPTP PF03736.17 EKX52840.1 - 6.6e-29 99.6 14.3 0.00011 22.1 0.1 10.6 11 0 0 11 11 11 8 EPTP domain Lactonase PF10282.9 EKX52840.1 - 2.2e-12 46.9 0.0 0.0057 16.0 0.0 5.4 5 0 0 5 5 5 3 Lactonase, 7-bladed beta-propeller TIG PF01833.24 EKX52840.1 - 2.5e-10 40.3 1.0 2.5e-10 40.3 1.0 6.0 5 0 0 5 5 5 1 IPT/TIG domain Big_9 PF17963.1 EKX52840.1 - 7.8e-10 39.4 20.1 0.0046 17.7 0.4 11.3 14 0 0 14 14 14 2 Bacterial Ig domain Laminin_G_3 PF13385.6 EKX52840.1 - 0.015 15.4 0.1 0.18 11.9 0.1 3.0 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily M-factor PF03855.13 EKX52840.1 - 0.13 12.4 0.1 0.71 10.1 0.1 2.3 1 0 0 1 1 1 0 M-factor DUF5122 PF17164.4 EKX52840.1 - 2.6 8.4 8.5 1.1e+02 3.2 0.2 5.6 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller Ion_trans PF00520.31 EKX52841.1 - 5.8e-33 114.1 18.9 1.1e-32 113.2 18.9 1.4 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EKX52841.1 - 6.2e-11 41.6 15.5 7.4e-10 38.1 7.0 2.2 1 1 1 2 2 2 2 Polycystin cation channel EF-hand_6 PF13405.6 EKX52841.1 - 0.00021 20.9 0.1 0.0014 18.4 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EKX52841.1 - 0.0003 20.1 3.0 0.00071 18.9 0.0 3.2 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 EKX52841.1 - 0.00041 19.7 0.1 0.0013 18.1 0.1 1.9 1 0 0 1 1 1 1 EF hand PH PF00169.29 EKX52841.1 - 0.00061 20.3 0.0 0.0015 19.0 0.0 1.8 1 1 0 1 1 1 1 PH domain EF-hand_7 PF13499.6 EKX52841.1 - 0.0012 19.2 0.1 0.012 16.1 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair HD_assoc PF13286.6 EKX52841.1 - 0.027 15.0 1.2 0.061 13.9 1.2 1.6 1 0 0 1 1 1 0 Phosphohydrolase-associated domain EF-hand_8 PF13833.6 EKX52841.1 - 0.078 12.8 0.2 0.28 11.1 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair Alpha_Helical PF18489.1 EKX52841.1 - 0.081 13.1 0.3 0.27 11.4 0.3 1.9 1 0 0 1 1 1 0 Alpha helical domain VirB7 PF17413.2 EKX52841.1 - 0.18 11.2 0.0 0.46 9.8 0.0 1.7 1 0 0 1 1 1 0 Outer membrane lipoprotein virB7 Methyltransf_21 PF05050.12 EKX52842.1 - 1.7e-09 37.9 0.0 2.9e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain DNA_pol3_delta2 PF13177.6 EKX52843.1 - 7.6e-11 42.1 0.1 1.9e-10 40.8 0.1 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 EKX52843.1 - 2.7e-09 37.6 0.0 6.1e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 EKX52843.1 - 1.8e-05 25.0 0.6 5.5e-05 23.5 0.0 2.1 3 0 0 3 3 3 1 Replication factor C C-terminal domain RuvB_N PF05496.12 EKX52843.1 - 0.00094 19.0 0.0 0.0044 16.8 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 EKX52843.1 - 0.001 19.0 0.0 0.0021 18.0 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 EKX52843.1 - 0.0027 17.9 0.1 0.036 14.2 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 EKX52843.1 - 0.017 15.5 0.0 0.15 12.5 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 EKX52843.1 - 0.017 15.1 0.0 0.042 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EKX52843.1 - 0.06 13.6 0.0 0.26 11.5 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_11 PF13086.6 EKX52843.1 - 0.095 12.5 0.1 0.19 11.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 EKX52843.1 - 0.097 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 EKX52843.1 - 0.11 11.9 0.1 0.48 9.8 0.1 2.0 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EKX52843.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DHHC PF01529.20 EKX52844.1 - 1.9e-31 108.9 15.8 3.4e-31 108.1 15.8 1.4 1 1 0 1 1 1 1 DHHC palmitoyltransferase Arteri_Gl PF00951.18 EKX52845.1 - 0.12 12.2 2.9 0.15 11.9 2.9 1.2 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein EI24 PF07264.11 EKX52845.1 - 0.18 12.1 7.0 0.22 11.8 7.0 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) TPR_1 PF00515.28 EKX52846.1 - 5.3e-06 26.0 2.6 0.012 15.4 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX52846.1 - 1.4e-05 24.8 1.5 1.1 9.5 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat MIT PF04212.18 EKX52846.1 - 0.0095 16.0 1.1 0.017 15.2 1.1 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 EKX52846.1 - 0.011 16.3 0.1 0.036 14.6 0.1 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX52846.1 - 0.018 15.6 1.5 9.7 7.1 0.1 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX52846.1 - 0.023 14.8 0.2 0.098 12.7 0.0 2.1 1 1 2 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF4911 PF16256.5 EKX52846.1 - 0.065 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) Helicase_C_2 PF13307.6 EKX52847.1 - 3.8e-55 186.7 0.0 7.1e-55 185.8 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 EKX52847.1 - 5e-50 169.6 0.6 8.3e-50 168.8 0.6 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 EKX52847.1 - 3.5e-05 23.9 0.0 0.017 15.1 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 EKX52847.1 - 0.00027 20.7 0.0 0.2 11.4 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase SNF2_N PF00176.23 EKX52847.1 - 0.0081 14.9 0.1 0.019 13.7 0.1 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain bZIP_2 PF07716.15 EKX52848.1 - 4.3e-09 36.3 4.8 4.3e-09 36.3 4.8 2.7 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 EKX52848.1 - 2.4e-07 30.8 12.7 5.2e-07 29.7 9.5 2.5 2 1 1 3 3 3 1 bZIP transcription factor bZIP_Maf PF03131.17 EKX52848.1 - 0.0015 19.0 6.3 0.0027 18.2 6.3 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Shugoshin_N PF07558.11 EKX52848.1 - 0.061 13.2 7.7 0.31 10.9 0.3 3.2 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region YabA PF06156.13 EKX52848.1 - 0.1 13.2 1.9 0.13 12.9 0.7 1.8 2 1 0 2 2 2 0 Initiation control protein YabA OsmC PF02566.19 EKX52849.1 - 1.8e-10 41.2 0.0 2.7e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 OsmC-like protein Glyco_hydro_47 PF01532.20 EKX52850.1 - 5.9e-98 328.7 0.0 8.3e-98 328.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GST_N_3 PF13417.6 EKX52852.1 - 0.00086 19.7 0.0 0.0016 18.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EKX52852.1 - 0.015 15.6 0.1 0.031 14.6 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 EKX52852.1 - 0.031 14.5 0.3 0.067 13.4 0.1 1.7 2 0 0 2 2 2 0 Glutaredoxin GST_C_3 PF14497.6 EKX52852.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CBS PF00571.28 EKX52854.1 - 1.2e-25 89.7 0.1 9.3e-10 38.8 0.1 4.4 4 0 0 4 4 4 4 CBS domain Aminotran_4 PF01063.19 EKX52855.1 - 2e-18 67.1 0.0 2.6e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Actin PF00022.19 EKX52858.1 - 5.2e-56 190.0 0.0 5.6e-53 180.0 0.0 2.9 1 1 0 1 1 1 1 Actin Peptidase_C1 PF00112.23 EKX52859.1 - 2.6e-94 315.4 12.2 6.6e-49 166.9 3.3 2.3 2 0 0 2 2 2 2 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EKX52859.1 - 0.19 10.5 9.6 1 8.0 0.3 3.7 4 0 0 4 4 4 0 Peptidase C1-like family UBX PF00789.20 EKX52860.1 - 6.8e-15 55.0 0.0 1.3e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 EKX52860.1 - 2.5e-10 40.0 0.1 5.8e-10 38.8 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 EKX52860.1 - 0.0056 16.3 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 TAP C-terminal domain Thioredoxin_7 PF13899.6 EKX52860.1 - 0.035 14.3 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin-like TagF_N PF09867.9 EKX52860.1 - 0.053 13.6 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 TagF N-terminal domain, Type VI secretion system-associated Glycos_transf_2 PF00535.26 EKX52861.1 - 4.8e-08 33.0 0.0 6.6e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EKX52861.1 - 3.1e-05 24.0 0.0 5.7e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Herpes_UL36 PF03586.13 EKX52862.1 - 0.048 13.0 1.5 0.08 12.2 0.9 1.7 1 1 0 1 1 1 0 Herpesvirus UL36 tegument protein ATG16 PF08614.11 EKX52862.1 - 0.11 12.7 38.5 0.98 9.6 2.3 4.0 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) YabA PF06156.13 EKX52862.1 - 0.66 10.6 25.9 0.81 10.4 0.1 4.6 3 1 2 5 5 5 0 Initiation control protein YabA SKA1 PF07160.12 EKX52862.1 - 1 9.1 21.3 0.63 9.8 0.1 4.0 3 1 0 3 3 3 0 Spindle and kinetochore-associated protein 1 Aminotran_1_2 PF00155.21 EKX52863.1 - 8.8e-05 21.8 0.0 0.00042 19.6 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II LRR_6 PF13516.6 EKX52864.1 - 2.1e-08 33.5 0.1 0.01 15.8 0.0 2.9 3 0 0 3 3 3 2 Leucine Rich repeat zf-C3HC4_3 PF13920.6 EKX52864.1 - 0.0057 16.5 14.2 0.025 14.4 14.2 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX52864.1 - 0.037 13.9 7.2 0.079 12.8 7.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EKX52864.1 - 0.077 13.0 7.4 0.19 11.8 7.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EKX52864.1 - 0.1 12.5 11.5 0.034 14.0 4.9 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SUIM_assoc PF16619.5 EKX52864.1 - 0.15 12.1 8.1 0.42 10.7 8.1 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TPR_12 PF13424.6 EKX52865.1 - 0.0023 18.2 20.0 1.9 8.8 0.3 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat DUF4111 PF13427.6 EKX52865.1 - 0.012 15.8 25.5 2.4 8.4 2.1 5.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4111) RHH_4 PF13467.6 EKX52865.1 - 0.013 15.3 21.7 0.28 11.1 0.8 4.9 5 0 0 5 5 5 0 Ribbon-helix-helix domain Fib_alpha PF08702.10 EKX52865.1 - 0.5 10.5 72.0 1.8 8.7 3.8 6.1 1 1 5 6 6 6 0 Fibrinogen alpha/beta chain family DUF356 PF04009.12 EKX52865.1 - 4.2 7.7 13.1 83 3.5 0.1 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF356) Baculo_PEP_N PF04512.12 EKX52865.1 - 6.6 7.1 14.0 1.3e+02 2.9 0.1 5.7 1 1 6 8 8 8 0 Baculovirus polyhedron envelope protein, PEP, N terminus DUF4025 PF13217.6 EKX52865.1 - 8.7 6.3 17.2 42 4.1 0.8 4.9 4 0 0 4 4 4 0 Protein of unknown function (DUF4025) SAF PF08666.12 EKX52866.1 - 0.09 13.4 0.0 0.21 12.2 0.0 1.6 1 0 0 1 1 1 0 SAF domain RB_B PF01857.20 EKX52866.1 - 0.14 12.2 0.2 0.16 12.0 0.2 1.1 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain FlxA PF14282.6 EKX52868.1 - 0.051 13.6 1.0 0.67 10.0 0.2 2.1 2 0 0 2 2 2 0 FlxA-like protein Med9 PF07544.13 EKX52868.1 - 0.069 13.3 4.6 0.35 11.0 4.5 2.0 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Phi-29_GP4 PF05464.11 EKX52868.1 - 0.069 13.4 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) Prok-E2_C PF14459.6 EKX52869.1 - 0.063 13.4 0.1 0.074 13.2 0.1 1.0 1 0 0 1 1 1 0 Prokaryotic E2 family C Retrotrans_gag PF03732.17 EKX52872.1 - 5.5e-05 23.4 1.1 7.6e-05 22.9 0.1 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein RE_MamI PF09567.10 EKX52872.1 - 0.022 14.4 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 MamI restriction endonuclease MKT1_N PF12247.8 EKX52872.1 - 0.022 15.1 0.0 0.04 14.3 0.0 1.4 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication Gag_p24 PF00607.20 EKX52872.1 - 0.036 13.9 0.1 0.091 12.6 0.1 1.8 1 1 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) TPR_12 PF13424.6 EKX52873.1 - 0.00037 20.7 3.6 1.9 8.8 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX52873.1 - 0.014 15.6 2.7 1.7 9.0 0.0 4.3 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Bac_chlorC PF02043.17 EKX52873.1 - 0.26 11.3 1.2 3.3 7.8 0.6 2.9 2 1 0 2 2 2 0 Bacteriochlorophyll C binding protein WD40 PF00400.32 EKX52875.1 - 7.1e-07 29.8 0.4 0.00064 20.5 0.1 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX52875.1 - 8.6e-07 29.2 1.7 1.6 9.1 0.0 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain SMC_N PF02463.19 EKX52876.1 - 0.00038 20.0 0.0 0.00072 19.0 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EKX52876.1 - 0.0015 18.7 0.0 0.003 17.8 0.0 1.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DHR10 PF18595.1 EKX52876.1 - 0.0098 15.9 6.1 0.0098 15.9 6.1 2.7 3 0 0 3 3 3 1 Designed helical repeat protein 10 domain Spc24 PF08286.11 EKX52876.1 - 0.01 16.1 12.1 0.25 11.6 0.9 2.9 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 FRB_dom PF08771.11 EKX52876.1 - 0.044 14.2 6.3 0.31 11.5 0.4 2.9 3 0 0 3 3 3 0 FKBP12-rapamycin binding domain Uds1 PF15456.6 EKX52876.1 - 0.062 13.5 0.4 0.062 13.5 0.4 2.7 2 1 0 2 2 2 0 Up-regulated During Septation Cep57_MT_bd PF06657.13 EKX52876.1 - 0.17 12.4 8.6 0.27 11.7 1.0 2.8 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF641 PF04859.12 EKX52876.1 - 0.23 11.8 7.9 8.7 6.7 1.5 3.3 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) Occludin_ELL PF07303.13 EKX52876.1 - 0.77 10.5 19.3 2.1 9.1 8.4 3.0 1 1 1 2 2 2 0 Occludin homology domain DUF1664 PF07889.12 EKX52876.1 - 3.3 7.8 9.6 5 7.2 0.5 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 EKX52876.1 - 3.9 8.0 10.3 0.29 11.6 1.9 3.0 4 0 0 4 4 3 0 Nucleopolyhedrovirus P10 protein MukF_M PF17192.4 EKX52877.1 - 0.019 14.7 0.5 0.3 10.8 0.1 2.6 2 1 1 3 3 3 0 MukF middle domain Synaptobrevin PF00957.21 EKX52878.1 - 0.57 10.0 5.9 0.77 9.6 1.3 2.8 1 1 1 2 2 2 0 Synaptobrevin CDC45 PF02724.14 EKX52878.1 - 0.81 7.9 29.3 0.88 7.8 29.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4407 PF14362.6 EKX52878.1 - 2.4 7.4 30.8 3.1 7.0 30.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4407 PF14362.6 EKX52879.1 - 0.26 10.6 27.4 0.3 10.4 27.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ISG65-75 PF11727.8 EKX52879.1 - 1.3 8.2 34.3 0.41 9.8 30.7 1.9 2 0 0 2 2 2 0 Invariant surface glycoprotein Neur_chan_memb PF02932.16 EKX52879.1 - 3.2 7.7 14.3 4.4 7.3 14.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4407 PF14362.6 EKX52880.1 - 0.95 8.7 30.3 1.3 8.3 30.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDC45 PF02724.14 EKX52880.1 - 3.5 5.8 26.5 3.8 5.7 26.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Phage_int_SAM_2 PF12834.7 EKX52881.1 - 0.31 11.7 3.5 48 4.7 0.0 4.0 2 2 1 4 4 4 0 Phage integrase, N-terminal DUF4407 PF14362.6 EKX52882.1 - 0.13 11.6 24.5 0.15 11.4 24.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ISG65-75 PF11727.8 EKX52882.1 - 0.84 8.8 31.3 0.25 10.6 27.7 1.7 2 0 0 2 2 2 0 Invariant surface glycoprotein CDC45 PF02724.14 EKX52882.1 - 3.5 5.8 19.3 3.8 5.7 19.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.16 EKX52882.1 - 6.7 6.7 12.4 9 6.3 12.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Mitofilin PF09731.9 EKX52883.1 - 0.26 10.1 43.4 0.32 9.8 43.4 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CDC45 PF02724.14 EKX52883.1 - 0.32 9.2 32.5 0.35 9.1 32.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 EKX52883.1 - 0.92 8.2 27.1 1.1 7.9 27.1 1.3 1 0 0 1 1 1 0 Presenilin Raftlin PF15250.6 EKX52883.1 - 7.6 5.2 21.7 8.3 5.0 21.7 1.3 1 0 0 1 1 1 0 Raftlin Hid1 PF12722.7 EKX52883.1 - 9 4.3 25.9 9.8 4.2 25.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein bZIP_1 PF00170.21 EKX52884.1 - 0.00032 20.7 61.1 0.46 10.6 4.7 7.6 5 2 3 8 8 8 6 bZIP transcription factor ZapB PF06005.12 EKX52884.1 - 0.00065 20.1 58.8 0.058 13.8 1.2 7.1 3 1 2 5 5 5 4 Cell division protein ZapB KASH_CCD PF14662.6 EKX52884.1 - 0.0013 18.6 58.8 0.18 11.6 25.3 3.7 1 1 2 3 3 3 2 Coiled-coil region of CCDC155 or KASH HOOK PF05622.12 EKX52884.1 - 0.062 11.5 55.5 0.026 12.7 50.6 2.0 1 1 1 2 2 2 0 HOOK protein YabA PF06156.13 EKX52884.1 - 0.54 10.9 55.5 1.2 9.8 5.6 5.7 1 1 4 5 5 5 0 Initiation control protein YabA HAUS-augmin3 PF14932.6 EKX52884.1 - 2.8 7.4 43.0 0.11 12.1 8.2 3.3 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 3 CENP-F_leu_zip PF10473.9 EKX52884.1 - 3.8 7.5 57.1 0.23 11.5 17.6 4.7 1 1 4 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_LEF-2 PF03041.14 EKX52884.1 - 5.3 6.7 10.7 0.52 10.0 0.8 2.6 1 1 1 2 2 2 0 lef-2 MgtE_N PF03448.17 EKX52885.1 - 0.2 12.3 2.9 11 6.7 0.0 3.0 3 0 0 3 3 3 0 MgtE intracellular N domain Trypan_PARP PF05887.11 EKX52886.1 - 0.039 13.9 9.0 0.059 13.4 9.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2254 PF10011.9 EKX52886.1 - 1.2 7.8 5.7 5.4 5.7 2.8 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) SAPS PF04499.15 EKX52886.1 - 3.2 6.4 14.1 3.7 6.2 14.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 EKX52886.1 - 9.9 4.3 18.4 10 4.3 18.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SNRNP27 PF08648.12 EKX52887.1 - 3.5e-09 36.6 0.4 3.5e-09 36.6 0.4 2.4 1 1 1 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins Ephrin_rec_like PF07699.13 EKX52888.1 - 7e-38 128.2 115.1 3.1e-08 33.3 8.5 10.7 8 2 2 10 10 10 10 Putative ephrin-receptor like EGF_MSP1_1 PF12946.7 EKX52888.1 - 0.03 14.4 51.5 0.2 11.7 2.3 9.2 6 3 2 8 8 8 0 MSP1 EGF domain 1 Pneumo_NS1 PF03438.13 EKX52888.1 - 1.1 9.3 4.4 8.3 6.6 0.1 2.8 3 0 0 3 3 3 0 Pneumovirus NS1 protein Rubrerythrin PF02915.17 EKX52889.1 - 2.3e-21 76.6 0.6 5e-21 75.5 0.6 1.5 1 1 0 1 1 1 1 Rubrerythrin Ferritin PF00210.24 EKX52889.1 - 1e-05 25.5 1.1 0.092 12.7 0.2 2.1 1 1 1 2 2 2 2 Ferritin-like domain Ferritin_2 PF13668.6 EKX52889.1 - 0.00083 19.6 0.7 0.0011 19.1 0.7 1.2 1 0 0 1 1 1 1 Ferritin-like domain DUF3712 PF12505.8 EKX52890.1 - 2e-15 57.1 4.8 2.2e-06 27.9 0.0 5.0 5 0 0 5 5 5 3 Protein of unknown function (DUF3712) LEA_2 PF03168.13 EKX52890.1 - 1.8e-07 31.6 0.1 0.00086 19.8 0.0 4.1 6 0 0 6 6 6 2 Late embryogenesis abundant protein PAS_4 PF08448.10 EKX52890.1 - 0.027 14.7 0.0 0.12 12.6 0.0 2.1 2 0 0 2 2 2 0 PAS fold PHD PF00628.29 EKX52891.1 - 1.8e-13 50.2 6.0 3.8e-13 49.1 6.0 1.6 1 0 0 1 1 1 1 PHD-finger C1_2 PF03107.16 EKX52891.1 - 0.042 14.2 4.2 0.16 12.3 1.5 2.4 2 0 0 2 2 2 0 C1 domain zf-HC5HC2H PF13771.6 EKX52891.1 - 0.061 13.6 4.1 0.21 11.9 4.1 2.0 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EKX52891.1 - 0.073 13.2 0.2 0.18 12.0 0.2 1.7 1 0 0 1 1 1 0 PHD-zinc-finger like domain Prok-RING_1 PF14446.6 EKX52891.1 - 0.095 12.6 3.3 0.32 11.0 3.3 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 EKX52891.1 - 0.61 9.7 5.5 0.065 12.8 0.7 1.8 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain DZR PF12773.7 EKX52891.1 - 0.9 9.6 4.6 56 3.9 4.7 2.5 1 1 0 1 1 1 0 Double zinc ribbon Zf_RING PF16744.5 EKX52891.1 - 2.1 8.5 7.0 0.11 12.6 0.8 2.1 2 0 0 2 2 2 0 KIAA1045 RING finger Prim_Zn_Ribbon PF08273.12 EKX52891.1 - 2.6 8.4 6.6 0.65 10.3 1.7 2.4 2 1 0 2 2 2 0 Zinc-binding domain of primase-helicase Bromodomain PF00439.25 EKX52892.1 - 1.5e-16 60.3 0.0 2e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 EKX52893.1 - 0.0059 16.5 16.4 0.19 11.7 16.6 2.4 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 EKX52893.1 - 0.044 14.1 21.1 0.11 12.9 18.6 2.3 3 0 0 3 3 3 0 Ring finger domain Zf_RING PF16744.5 EKX52893.1 - 0.7 10.0 12.5 4.4 7.5 12.5 2.1 2 0 0 2 2 2 0 KIAA1045 RING finger zf-RING_11 PF17123.5 EKX52893.1 - 3.3 7.5 17.0 0.4 10.5 6.9 3.1 3 0 0 3 3 3 0 RING-like zinc finger PseudoU_synth_2 PF00849.22 EKX52894.1 - 3.6e-25 88.9 0.0 5.2e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF3375 PF11855.8 EKX52894.1 - 0.092 11.7 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) Utp11 PF03998.13 EKX52894.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 Utp11 protein NAD_binding_10 PF13460.6 EKX52895.1 - 7.6e-31 107.4 0.0 3.7e-27 95.4 0.0 2.2 1 1 1 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 EKX52895.1 - 6.2e-07 29.2 0.0 0.0054 16.3 0.0 2.7 1 1 1 2 2 2 2 NmrA-like family Epimerase PF01370.21 EKX52895.1 - 0.0019 17.7 0.0 0.0076 15.7 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EKX52895.1 - 0.017 14.1 0.1 3 6.8 0.1 2.2 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family COG5 PF10392.9 EKX52896.1 - 0.07 13.3 7.7 0.07 13.3 5.2 2.0 1 1 1 2 2 2 0 Golgi transport complex subunit 5 HALZ PF02183.18 EKX52896.1 - 0.081 13.2 2.3 13 6.1 0.1 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF1664 PF07889.12 EKX52896.1 - 0.12 12.4 0.9 0.28 11.2 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF1515 PF07439.11 EKX52896.1 - 0.27 11.3 0.8 1.6 8.8 1.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1515) Fib_alpha PF08702.10 EKX52896.1 - 0.66 10.1 8.6 0.43 10.8 6.5 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Eapp_C PF10238.9 EKX52896.1 - 1.6 8.8 7.1 0.26 11.4 2.7 1.9 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF4094 PF13334.6 EKX52896.1 - 1.8 9.1 7.6 0.14 12.6 2.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) YabA PF06156.13 EKX52896.1 - 6.8 7.4 9.8 0.44 11.2 1.0 2.9 2 1 1 3 3 3 0 Initiation control protein YabA SOGA PF11365.8 EKX52896.1 - 7.1 7.8 11.5 0.11 13.6 2.2 2.7 2 1 0 2 2 2 0 Protein SOGA HEAT PF02985.22 EKX52897.1 - 1.5e-10 40.4 1.6 0.00017 21.6 0.0 5.5 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 EKX52897.1 - 5.6e-09 36.3 0.1 0.00083 19.7 0.0 4.0 3 1 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 EKX52897.1 - 0.0026 18.2 0.0 1.2 9.7 0.0 3.4 2 1 1 3 3 3 1 HEAT-like repeat Cnd1 PF12717.7 EKX52897.1 - 0.037 14.1 6.8 6.7 6.7 0.0 4.2 2 1 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 PseudoU_synth_2 PF00849.22 EKX52898.1 - 5.5e-29 101.3 0.1 7.5e-29 100.9 0.1 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase RRM_1 PF00076.22 EKX52899.1 - 4.5e-37 125.7 4.5 9.5e-09 35.0 0.0 5.6 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EKX52899.1 - 2.3e-10 40.2 1.2 0.00025 20.8 0.0 4.4 4 0 0 4 4 4 3 Occluded RNA-recognition motif Limkain-b1 PF11608.8 EKX52899.1 - 4.5e-06 26.6 4.4 1.1 9.3 0.0 5.4 5 0 0 5 5 5 2 Limkain b1 DUF1866 PF08952.11 EKX52899.1 - 0.0011 18.9 0.4 0.31 10.9 0.0 3.5 2 1 2 4 4 4 1 Domain of unknown function (DUF1866) Nup35_RRM_2 PF14605.6 EKX52899.1 - 0.016 15.2 1.4 2.6 8.1 0.0 3.9 4 1 0 4 4 4 0 Nup53/35/40-type RNA recognition motif DUF4283 PF14111.6 EKX52899.1 - 0.038 13.5 0.0 13 5.3 0.0 3.2 2 1 0 3 3 3 0 Domain of unknown function (DUF4283) SNN_cytoplasm PF09051.10 EKX52899.1 - 0.83 9.5 3.7 0.86 9.5 0.2 2.6 2 0 0 2 2 2 0 Stannin cytoplasmic Zip PF02535.22 EKX52899.1 - 8.8 5.4 9.4 18 4.4 9.4 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter Glyco_transf_20 PF00982.21 EKX52900.1 - 6.5e-101 338.3 0.0 8e-101 338.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EKX52900.1 - 5.6e-34 117.3 0.0 1e-33 116.4 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase PLAC8 PF04749.17 EKX52902.1 - 1.1e-05 26.3 19.3 0.00013 22.9 19.2 2.1 1 1 0 1 1 1 1 PLAC8 family UPF0203 PF05254.12 EKX52903.1 - 0.16 12.2 0.2 0.16 12.2 0.2 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0203) DUF728 PF05304.12 EKX52903.1 - 7.2 6.4 7.8 12 5.8 6.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF728) OCRE PF17780.1 EKX52904.1 - 0.016 15.2 0.5 0.037 14.0 0.5 1.6 1 0 0 1 1 1 0 OCRE domain CortBP2 PF09727.9 EKX52904.1 - 0.64 9.9 7.9 1.3 8.9 0.2 2.4 1 1 1 2 2 2 0 Cortactin-binding protein-2 XPG_I PF00867.18 EKX52905.1 - 1.4e-21 76.7 0.0 2.2e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EKX52905.1 - 7.5e-20 71.3 0.0 1.7e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 EKX52905.1 - 0.00011 21.7 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing EF-hand_1 PF00036.32 EKX52906.1 - 1.1e-41 137.3 12.9 3.5e-10 38.7 1.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EKX52906.1 - 7.5e-36 122.4 3.1 3.5e-18 65.8 1.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EKX52906.1 - 1.5e-31 108.0 11.3 2.2e-15 56.2 0.8 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EKX52906.1 - 3.9e-30 101.2 7.1 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EKX52906.1 - 3.3e-27 92.7 10.0 2.1e-06 27.0 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EKX52906.1 - 7.5e-16 58.2 0.2 3.3e-09 37.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EKX52906.1 - 6.5e-10 38.9 0.6 9.7e-05 22.3 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EKX52906.1 - 4.1e-08 33.5 0.3 0.004 17.4 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 EKX52906.1 - 1.8e-06 28.8 0.0 0.00047 21.0 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 EKX52906.1 - 1.8e-05 24.7 0.3 0.042 13.9 0.0 3.1 3 1 0 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 EKX52906.1 - 5.4e-05 23.2 1.1 0.00026 21.0 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 EKX52906.1 - 0.0002 21.5 3.7 0.06 13.5 0.3 2.9 1 1 1 2 2 2 2 Dockerin type I domain DUF3349 PF11829.8 EKX52906.1 - 0.0011 19.7 0.5 1.2 10.0 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) TerB PF05099.13 EKX52906.1 - 0.0014 18.6 0.4 0.49 10.3 0.0 2.3 1 1 1 2 2 2 1 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.16 EKX52906.1 - 0.0022 18.3 0.1 1.4 9.3 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb4 Caleosin PF05042.13 EKX52906.1 - 0.0024 17.8 0.8 0.44 10.5 0.0 3.3 1 1 3 4 4 4 1 Caleosin related protein DUF1103 PF06513.11 EKX52906.1 - 0.0042 16.7 1.8 0.0048 16.5 1.8 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) SurA_N_2 PF13623.6 EKX52906.1 - 0.016 15.0 0.5 1 9.2 0.1 2.2 1 1 1 2 2 2 0 SurA N-terminal domain MotA_activ PF09114.10 EKX52906.1 - 0.016 15.3 0.4 0.25 11.5 0.1 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain Poly_export PF02563.16 EKX52906.1 - 0.02 15.1 0.1 3.7 7.8 0.0 3.1 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 EKX52906.1 - 0.021 15.3 0.0 6.9 7.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4497) DUF853 PF05872.12 EKX52906.1 - 0.029 13.0 0.1 0.79 8.2 0.0 2.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF853) EF-hand_14 PF17959.1 EKX52906.1 - 0.044 14.1 0.1 9.3 6.7 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain Fe_hyd_lg_C PF02906.14 EKX52906.1 - 0.053 13.2 0.6 0.19 11.4 0.6 1.8 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain dCache_2 PF08269.11 EKX52906.1 - 0.064 12.4 0.1 5.2 6.1 0.0 2.2 1 1 1 2 2 2 0 Cache domain DUF5580 PF17743.1 EKX52906.1 - 0.098 11.2 0.0 0.098 11.2 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) SapB_1 PF05184.15 EKX52906.1 - 0.22 11.6 2.7 27 4.9 0.0 3.5 4 0 0 4 4 4 0 Saposin-like type B, region 1 OCRE PF17780.1 EKX52907.1 - 0.032 14.2 1.5 6.3 6.9 0.2 2.3 1 1 0 2 2 2 0 OCRE domain Jnk-SapK_ap_N PF09744.9 EKX52907.1 - 0.2 11.9 14.7 0.41 10.8 14.7 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 UPF0242 PF06785.11 EKX52907.1 - 0.71 10.0 9.9 1.2 9.2 9.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 EKX52907.1 - 1 9.9 20.3 0.055 14.0 11.1 2.9 3 0 0 3 3 3 0 Apg6 coiled-coil region V_ATPase_I PF01496.19 EKX52907.1 - 2.7 5.8 6.0 4.4 5.1 6.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 EKX52907.1 - 2.7 6.8 15.3 6 5.7 15.1 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein TMPIT PF07851.13 EKX52907.1 - 3.6 6.7 4.9 5 6.3 4.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein Macoilin PF09726.9 EKX52908.1 - 6.5 5.2 19.3 8 4.9 19.3 1.1 1 0 0 1 1 1 0 Macoilin family CENP-H PF05837.12 EKX52908.1 - 7.2 7.1 14.0 0.072 13.5 1.5 2.8 3 0 0 3 3 3 0 Centromere protein H (CENP-H) BRO1 PF03097.18 EKX52909.1 - 4.9e-23 81.6 0.2 6.5e-23 81.2 0.2 1.1 1 0 0 1 1 1 1 BRO1-like domain Csa1 PF06023.12 EKX52910.1 - 0.0031 16.9 0.0 0.0093 15.3 0.0 1.8 1 0 0 1 1 1 1 CRISPR-associated exonuclease Csa1 KilA-N PF04383.13 EKX52910.1 - 0.098 12.5 2.1 2.6 7.9 0.0 2.9 2 0 0 2 2 2 0 KilA-N domain GPR15L PF15854.5 EKX52910.1 - 0.43 10.8 3.6 0.81 10.0 0.1 2.8 2 0 0 2 2 2 0 G-protein coupled receptor ligand 15 EF-hand_7 PF13499.6 EKX52911.1 - 1.3e-12 48.0 9.8 6.2e-10 39.4 3.3 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX52911.1 - 2.8e-11 42.1 7.5 1.2e-05 24.5 0.6 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EKX52911.1 - 1.6e-10 40.0 6.0 4e-05 23.2 0.3 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 EKX52911.1 - 1.8e-07 30.3 4.2 7.7e-05 22.0 0.8 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EKX52911.1 - 0.00028 20.7 4.0 0.0028 17.5 0.7 2.7 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX52911.1 - 0.0035 17.6 4.1 0.028 14.7 4.1 2.3 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Lectin_N PF03954.14 EKX52912.1 - 0.013 15.3 1.5 0.013 15.3 1.5 1.9 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain FeoB_Cyto PF17910.1 EKX52912.1 - 0.75 10.4 3.5 0.67 10.5 0.3 2.5 2 1 0 2 2 2 0 FeoB cytosolic helical domain DUF1664 PF07889.12 EKX52912.1 - 0.95 9.5 7.2 0.56 10.3 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) 5_nucleotid PF05761.14 EKX52912.1 - 1.3 7.8 8.9 0.087 11.7 3.6 1.6 2 0 0 2 2 2 0 5' nucleotidase family SecE PF00584.20 EKX52913.1 - 1.5e-13 50.4 0.1 1.7e-13 50.2 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Sterol-sensing PF12349.8 EKX52914.1 - 2e-12 47.2 7.8 4.2e-12 46.2 7.8 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation RINGv PF12906.7 EKX52914.1 - 7.7e-10 38.7 9.7 1.4e-09 37.9 9.7 1.4 1 0 0 1 1 1 1 RING-variant domain Patched PF02460.18 EKX52914.1 - 0.00029 19.1 0.3 0.00038 18.7 0.3 1.1 1 0 0 1 1 1 1 Patched family zf-Sec23_Sec24 PF04810.15 EKX52914.1 - 0.26 11.4 4.3 0.68 10.0 4.3 1.7 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger zf-RING-like PF08746.11 EKX52914.1 - 1.1 9.6 10.4 2.7 8.4 10.4 1.7 1 0 0 1 1 1 0 RING-like domain SAP PF02037.27 EKX52915.1 - 1.6e-08 34.1 0.1 1.6e-08 34.1 0.1 2.8 4 0 0 4 4 4 1 SAP domain TPR_1 PF00515.28 EKX52916.1 - 1.9e-12 46.5 4.0 1.5e-05 24.6 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX52916.1 - 7.3e-11 41.3 4.1 4.4e-06 26.4 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX52916.1 - 1.6e-06 27.7 3.1 0.014 15.0 0.2 3.2 2 1 1 3 3 3 2 TPR repeat TPR_9 PF13371.6 EKX52916.1 - 0.00014 22.0 0.2 0.0012 19.0 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX52916.1 - 0.00016 21.6 0.5 0.034 14.4 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX52916.1 - 0.00058 20.1 0.1 0.78 10.3 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX52916.1 - 0.0011 19.6 2.3 0.11 13.2 1.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX52916.1 - 0.0014 19.2 0.2 0.0049 17.4 0.2 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX52916.1 - 0.002 18.6 2.7 0.0064 17.0 1.8 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3846 PF12957.7 EKX52916.1 - 0.0041 17.4 0.0 0.0082 16.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3846) ANAPC3 PF12895.7 EKX52916.1 - 0.0095 16.1 3.4 0.024 14.9 2.2 2.2 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EKX52916.1 - 0.023 15.5 1.7 0.023 15.5 1.7 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX52916.1 - 0.15 12.0 0.5 0.89 9.5 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EKX52916.1 - 0.37 10.9 1.5 1.6 9.0 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX52916.1 - 0.92 9.8 4.2 0.95 9.8 0.2 2.7 3 1 0 3 3 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX52916.1 - 7.2 6.8 6.8 0.36 10.9 0.2 2.3 3 1 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat HAT_KAT11 PF08214.11 EKX52917.1 - 2.6e-08 33.5 0.0 8.1e-08 31.9 0.0 1.7 2 0 0 2 2 2 1 Histone acetylation protein DUF1722 PF08349.11 EKX52917.1 - 0.05 13.9 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) TAFH PF07531.14 EKX52917.1 - 0.18 11.9 0.2 0.75 9.9 0.1 2.1 2 0 0 2 2 2 0 NHR1 homology to TAF APC_N_CC PF16689.5 EKX52918.1 - 0.0035 17.4 0.0 0.0076 16.3 0.0 1.6 1 0 0 1 1 1 1 Coiled-coil N-terminus of APC, dimerisation domain DivIVA PF05103.13 EKX52918.1 - 0.033 14.3 0.2 0.049 13.7 0.2 1.2 1 0 0 1 1 1 0 DivIVA protein PC-Esterase PF13839.6 EKX52919.1 - 1.1e-05 25.4 0.0 0.0002 21.2 0.0 2.3 2 0 0 2 2 2 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p RRM_1 PF00076.22 EKX52920.1 - 1.8e-11 43.7 0.0 2.4e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EKX52920.1 - 0.00098 19.6 17.5 0.00098 19.6 17.5 3.7 2 2 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Btz PF09405.10 EKX52920.1 - 0.021 15.1 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding FHA PF00498.26 EKX52921.1 - 4e-07 30.3 0.4 1.5e-06 28.5 0.4 2.0 2 0 0 2 2 2 1 FHA domain Arg_tRNA_synt_N PF03485.16 EKX52921.1 - 0.4 11.3 2.3 0.72 10.5 0.1 2.4 2 0 0 2 2 2 0 Arginyl tRNA synthetase N terminal domain PMEI PF04043.15 EKX52921.1 - 0.64 10.4 12.2 0.058 13.7 1.7 2.4 1 1 1 2 2 2 0 Plant invertase/pectin methylesterase inhibitor TSC22 PF01166.18 EKX52921.1 - 1.2 9.5 6.2 6.5 7.1 0.5 2.9 1 1 1 2 2 2 0 TSC-22/dip/bun family MCPsignal PF00015.21 EKX52921.1 - 2 8.2 9.4 0.18 11.6 2.4 2.3 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FAM76 PF16046.5 EKX52921.1 - 2.5 7.4 26.3 0.13 11.6 10.2 2.6 1 1 1 2 2 2 0 FAM76 protein LRR_6 PF13516.6 EKX52922.1 - 2.2e-10 39.7 7.5 0.0037 17.2 0.7 3.1 3 0 0 3 3 3 3 Leucine Rich repeat LRR_4 PF12799.7 EKX52922.1 - 0.0039 17.6 2.8 0.39 11.2 0.2 2.4 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX52922.1 - 0.013 16.0 0.9 24 6.0 0.1 3.3 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.6 EKX52922.1 - 0.022 14.5 2.7 0.46 10.3 2.9 2.4 1 1 0 1 1 1 0 Leucine rich repeat Methyltransf_25 PF13649.6 EKX52923.1 - 2.5e-17 63.4 0.0 3.9e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX52923.1 - 9.2e-17 61.5 0.0 1.4e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX52923.1 - 2.9e-09 36.6 0.0 4.1e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EKX52923.1 - 3.2e-09 37.4 0.0 5.1e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX52923.1 - 3.2e-09 36.7 0.0 3.7e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX52923.1 - 3.9e-09 36.6 0.0 5.6e-09 36.0 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EKX52923.1 - 2.7e-06 26.9 0.0 3.4e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 EKX52923.1 - 3.9e-05 23.5 0.0 5.5e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 EKX52923.1 - 4.2e-05 23.4 0.0 5.3e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_4 PF02390.17 EKX52923.1 - 0.012 15.0 0.3 0.054 13.0 0.1 1.9 2 0 0 2 2 2 0 Putative methyltransferase DOT1 PF08123.13 EKX52923.1 - 0.027 14.0 0.0 0.048 13.2 0.0 1.4 1 1 0 1 1 1 0 Histone methylation protein DOT1 RrnaAD PF00398.20 EKX52923.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MetW PF07021.12 EKX52923.1 - 0.15 11.6 0.1 0.23 11.0 0.1 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.6 EKX52925.1 - 1.9e-18 66.7 0.0 1.2e-17 64.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX52925.1 - 3.3e-18 66.2 0.0 1.2e-17 64.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX52925.1 - 8.2e-17 61.5 0.0 1.4e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX52925.1 - 2.2e-15 57.1 0.0 6.9e-15 55.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX52925.1 - 4.9e-15 56.1 0.0 1.1e-14 54.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX52925.1 - 5.3e-09 35.8 0.0 7.7e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EKX52925.1 - 2.1e-07 30.6 0.0 4.7e-07 29.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 EKX52925.1 - 0.00042 19.8 0.0 0.0007 19.1 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.11 EKX52925.1 - 0.00043 19.3 0.0 0.00069 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_PK PF05891.12 EKX52925.1 - 0.0063 16.1 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase PrmA PF06325.13 EKX52925.1 - 0.007 15.8 0.0 0.017 14.5 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) XPA_C PF05181.12 EKX52925.1 - 0.016 15.2 0.1 1 9.4 0.0 3.1 3 0 0 3 3 3 0 XPA protein C-terminus Methyltransf_32 PF13679.6 EKX52925.1 - 0.018 15.0 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EKX52925.1 - 0.21 11.3 0.0 0.48 10.1 0.0 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) C2-C2_1 PF11618.8 EKX52926.1 - 4.5e-26 91.6 0.0 2.7e-21 76.1 0.0 5.2 6 0 0 6 6 6 1 First C2 domain of RPGR-interacting protein 1 RPGR1_C PF18111.1 EKX52926.1 - 2.9e-10 40.3 1.1 0.0028 17.6 0.0 4.5 4 0 0 4 4 4 2 Retinitis pigmentosa G-protein regulator interacting C-terminal C2 PF00168.30 EKX52926.1 - 7.1e-08 32.7 0.0 1.8e-06 28.2 0.0 3.1 2 0 0 2 2 2 1 C2 domain EF-hand_6 PF13405.6 EKX52926.1 - 0.003 17.4 2.4 0.91 9.6 0.2 3.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 EKX52926.1 - 0.0068 16.8 11.0 0.32 11.5 0.5 4.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX52926.1 - 0.021 14.4 8.5 0.037 13.6 1.6 3.9 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.6 EKX52926.1 - 0.022 14.6 5.5 0.044 13.6 0.8 3.4 3 1 1 4 4 4 0 EF-hand domain pair EF-hand_5 PF13202.6 EKX52926.1 - 0.039 13.5 6.6 0.022 14.2 2.0 2.9 2 0 0 2 2 2 0 EF hand DUF3138 PF11336.8 EKX52926.1 - 0.35 9.4 5.0 0.68 8.5 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) PseudoU_synth_1 PF01416.20 EKX52927.1 - 4.6e-28 97.8 0.0 8.5e-27 93.7 0.0 2.2 2 0 0 2 2 2 1 tRNA pseudouridine synthase Guanylate_cyc PF00211.20 EKX52928.1 - 1.7e-53 181.0 0.0 2.7e-53 180.3 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 EKX52928.1 - 1.7e-50 171.7 0.0 3.6e-47 160.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 EKX52928.1 - 5.4e-43 147.3 0.0 4.6e-39 134.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Phosphonate-bd PF12974.7 EKX52928.1 - 1.6e-23 83.6 0.1 2.9e-23 82.7 0.1 1.3 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein Kdo PF06293.14 EKX52928.1 - 0.0013 18.2 0.1 0.0023 17.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family NMT1 PF09084.11 EKX52928.1 - 0.0022 18.0 0.2 0.0045 17.0 0.2 1.4 1 0 0 1 1 1 1 NMT1/THI5 like APH PF01636.23 EKX52928.1 - 0.011 15.7 0.0 0.096 12.6 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Mobilization_B PF17511.2 EKX52928.1 - 0.015 15.7 0.4 0.031 14.7 0.4 1.4 1 0 0 1 1 1 0 Mobilization protein B Cytochrome_cB PF11783.8 EKX52928.1 - 0.024 14.5 0.1 0.052 13.4 0.1 1.4 1 0 0 1 1 1 0 Cytochrome c bacterial Phosphonate-bd PF12974.7 EKX52929.1 - 4.3e-22 78.9 0.2 5.3e-22 78.6 0.2 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 EKX52929.1 - 0.00021 21.3 0.2 0.00059 19.8 0.1 1.7 2 0 0 2 2 2 1 NMT1/THI5 like SBP_bac_3 PF00497.20 EKX52929.1 - 0.0022 17.4 0.3 0.006 16.0 0.1 1.8 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 AMPK1_CBM PF16561.5 EKX52929.1 - 0.042 14.1 0.0 0.072 13.3 0.0 1.3 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase Guanylate_cyc PF00211.20 EKX52930.1 - 1.7e-52 177.7 0.1 2.5e-52 177.1 0.1 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 EKX52930.1 - 7.6e-33 113.9 0.0 1.1e-32 113.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX52930.1 - 1.4e-27 96.7 0.0 2.3e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EKX52930.1 - 0.0093 15.9 0.1 0.025 14.5 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EKX52930.1 - 0.038 13.3 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TBP PF00352.21 EKX52931.1 - 0.00013 21.9 0.0 0.0002 21.2 0.0 1.5 1 1 0 1 1 1 1 Transcription factor TFIID (or TATA-binding protein, TBP) Myb_DNA-binding PF00249.31 EKX52933.1 - 3.9e-50 167.8 11.3 2.6e-18 66.0 0.6 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX52933.1 - 1.2e-40 137.6 5.7 7.1e-19 67.8 0.4 3.2 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 EKX52933.1 - 1.6e-07 31.4 0.0 0.31 11.1 0.0 3.1 1 1 2 3 3 3 3 SLIDE Myb_DNA-bind_7 PF15963.5 EKX52933.1 - 5.2e-06 26.3 0.1 0.0086 16.0 0.0 3.0 2 2 1 3 3 3 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EKX52933.1 - 9.2e-05 22.6 0.5 0.86 9.8 0.0 3.1 1 1 1 3 3 3 1 SANT/Myb-like domain of DAMP1 MADF_DNA_bdg PF10545.9 EKX52933.1 - 0.00078 19.7 3.1 0.32 11.3 0.2 3.2 3 0 0 3 3 3 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.8 EKX52933.1 - 0.0073 16.4 4.4 0.85 9.8 0.5 2.7 1 1 2 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 EKX52933.1 - 0.025 15.0 10.2 1.6 9.2 1.1 3.9 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain HTH_32 PF13565.6 EKX52933.1 - 0.08 13.6 1.6 3.7 8.2 0.2 2.5 1 1 1 2 2 2 0 Homeodomain-like domain DUP PF00674.18 EKX52933.1 - 0.15 12.2 1.0 48 4.2 0.0 3.1 3 0 0 3 3 3 0 DUP family Sigma70_r4_2 PF08281.12 EKX52933.1 - 0.17 11.6 0.0 0.78 9.5 0.0 2.1 3 0 0 3 3 3 0 Sigma-70, region 4 Collagen PF01391.18 EKX52936.1 - 5.3e-19 67.7 77.6 1.8e-09 37.2 38.8 2.7 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) MerR-DNA-bind PF09278.11 EKX52936.1 - 0.34 11.5 1.0 0.9 10.1 1.0 1.7 1 0 0 1 1 1 0 MerR, DNA binding SR-25 PF10500.9 EKX52937.1 - 1.3 8.6 5.5 1.8 8.1 5.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Fumerase_C PF05683.12 EKX52938.1 - 1.7e-83 279.0 0.0 1.8e-65 220.2 0.0 2.3 2 0 0 2 2 2 2 Fumarase C-terminus Fumerase PF05681.14 EKX52938.1 - 9.5e-75 251.5 0.0 2e-74 250.4 0.0 1.5 1 1 0 1 1 1 1 Fumarate hydratase (Fumerase) MORN PF02493.20 EKX52939.1 - 1.5e-22 78.1 41.9 3.2e-07 29.8 3.2 5.1 5 0 0 5 5 5 4 MORN repeat Thioredoxin PF00085.20 EKX52941.1 - 4e-24 84.6 0.0 5.2e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EKX52941.1 - 0.00041 20.8 0.0 0.00074 19.9 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EKX52941.1 - 0.0037 16.6 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EKX52941.1 - 0.0058 16.9 0.0 0.063 13.6 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like DUF1598 PF07643.11 EKX52942.1 - 0.056 13.7 0.3 0.42 10.9 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1598) Glyco_transf_10 PF00852.19 EKX52944.1 - 3.9e-25 88.6 0.0 8.5e-25 87.5 0.0 1.6 1 1 1 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term EF-hand_7 PF13499.6 EKX52945.1 - 7.3e-07 29.6 0.2 0.00023 21.5 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX52945.1 - 2.3e-05 24.0 0.2 0.11 12.5 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EKX52945.1 - 3.8e-05 22.9 0.7 0.54 9.9 0.2 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EKX52945.1 - 0.16 11.9 0.1 3.8 7.4 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain pair Asp-B-Hydro_N PF05279.11 EKX52945.1 - 1.6 8.7 28.5 2.4 8.2 28.5 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PDZ_6 PF17820.1 EKX52946.1 - 0.0003 20.6 0.0 0.00076 19.3 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX52946.1 - 0.0019 18.5 0.1 0.0053 17.1 0.1 1.7 1 0 0 1 1 1 1 PDZ domain DUF2026 PF09641.10 EKX52946.1 - 0.082 12.5 0.0 0.25 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2026) ATG16 PF08614.11 EKX52946.1 - 1.4 9.1 27.4 0.24 11.6 21.2 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Laminin_II PF06009.12 EKX52946.1 - 1.7 8.6 11.5 0.71 9.9 4.0 2.4 2 0 0 2 2 2 0 Laminin Domain II Iron_permease PF04120.12 EKX52946.1 - 1.8 8.3 5.6 1.6 8.5 2.9 2.3 1 1 1 2 2 2 0 Low affinity iron permease Ribosomal_60s PF00428.19 EKX52946.1 - 1.9 9.1 6.0 0.31 11.7 1.1 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Exonuc_VII_L PF02601.15 EKX52946.1 - 5.5 6.5 13.6 11 5.5 13.6 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0242 PF06785.11 EKX52946.1 - 5.8 7.0 19.7 14 5.7 19.7 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cation_ATPase_C PF00689.21 EKX52947.1 - 1.5e-43 148.7 0.3 1.5e-43 148.7 0.3 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EKX52947.1 - 5.2e-37 127.1 1.6 5.2e-37 127.1 1.6 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EKX52947.1 - 2.8e-19 70.2 2.1 2.9e-18 66.9 0.9 3.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EKX52947.1 - 5.8e-14 51.9 0.0 1.3e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EKX52947.1 - 8.7e-13 47.8 0.0 2.4e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EKX52947.1 - 1.5e-06 28.2 0.0 0.0001 22.2 0.1 2.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Phage_holin_3_6 PF07332.11 EKX52947.1 - 0.0035 17.4 4.9 0.054 13.5 0.6 2.8 2 0 0 2 2 2 1 Putative Actinobacterial Holin-X, holin superfamily III HAD PF12710.7 EKX52947.1 - 0.065 13.6 0.0 0.17 12.3 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase MORN PF02493.20 EKX52948.1 - 4e-23 79.9 38.5 2.2e-07 30.4 1.7 5.6 5 0 0 5 5 5 5 MORN repeat CF222 PF15661.5 EKX52952.1 - 0.14 11.0 0.1 10 4.9 0.0 2.0 2 0 0 2 2 2 0 C6orf222, uncharacterised family G-alpha PF00503.20 EKX52953.1 - 0.093 11.9 0.0 0.097 11.8 0.0 1.0 1 0 0 1 1 1 0 G-protein alpha subunit Nop14 PF04147.12 EKX52954.1 - 0.0013 17.1 24.5 0.0013 17.1 24.5 1.7 2 0 0 2 2 2 1 Nop14-like family Mpp10 PF04006.12 EKX52954.1 - 0.013 14.0 23.9 0.024 13.1 23.9 1.4 1 0 0 1 1 1 0 Mpp10 protein YL1 PF05764.13 EKX52954.1 - 0.03 14.5 21.7 0.099 12.7 21.7 1.9 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 EKX52954.1 - 0.057 11.7 18.6 0.1 10.9 18.6 1.4 1 0 0 1 1 1 0 CDC45-like protein BSP_II PF05432.11 EKX52954.1 - 0.15 11.7 24.9 0.23 11.1 24.9 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) RRN3 PF05327.11 EKX52954.1 - 3.7 6.0 28.0 1.6 7.2 24.8 1.9 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 EF-hand_1 PF00036.32 EKX52955.1 - 0.00072 18.9 4.8 0.0015 17.9 1.6 3.2 4 0 0 4 4 4 1 EF hand EF-hand_7 PF13499.6 EKX52955.1 - 0.0021 18.5 1.9 0.026 15.0 0.2 2.6 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX52955.1 - 0.021 14.7 1.5 0.55 10.3 0.5 3.3 3 0 0 3 3 3 0 EF-hand domain PD40 PF07676.12 EKX52955.1 - 0.093 12.7 0.2 1.4 9.0 0.3 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat EF-hand_8 PF13833.6 EKX52955.1 - 0.11 12.4 4.8 0.12 12.2 0.7 2.9 2 1 1 3 3 3 0 EF-hand domain pair Rieske PF00355.26 EKX52956.1 - 1.4e-06 28.1 0.0 1.9e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 EKX52956.1 - 0.017 15.0 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain TYW3 PF02676.14 EKX52957.1 - 0.06 12.7 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase TYW3 tRNA-synt_1c PF00749.21 EKX52958.1 - 3e-82 276.0 0.0 4.4e-82 275.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DUF1048 PF06304.11 EKX52958.1 - 0.01 16.3 0.6 0.035 14.6 0.5 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1048) Gpr1_Fun34_YaaH PF01184.19 EKX52960.1 - 2.3e-42 145.0 22.5 3.1e-42 144.5 22.5 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family PseudoU_synth_2 PF00849.22 EKX52962.1 - 2e-16 60.5 0.0 3.3e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase ubiquitin PF00240.23 EKX52963.1 - 0.00019 21.1 0.1 0.00032 20.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 EKX52963.1 - 0.0087 16.5 0.2 0.032 14.7 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain DUF640 PF04852.12 EKX52963.1 - 0.034 14.3 0.1 0.044 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF640) Exo_endo_phos PF03372.23 EKX52965.1 - 2e-13 50.4 0.0 3.2e-13 49.7 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Abhydrolase_1 PF00561.20 EKX52966.1 - 3e-16 59.9 0.0 5.8e-11 42.5 0.0 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EKX52966.1 - 2.3e-11 43.5 0.0 9.6e-08 31.6 0.0 2.5 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EKX52966.1 - 4.4e-05 23.3 0.0 7.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EKX52966.1 - 0.00034 20.5 0.0 0.0018 18.2 0.0 1.8 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.18 EKX52966.1 - 0.0054 16.3 0.0 0.014 14.9 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EKX52966.1 - 0.0069 17.0 0.0 0.022 15.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 EKX52966.1 - 0.0071 16.2 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Esterase PF00756.20 EKX52966.1 - 0.028 14.1 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase FSH1 PF03959.13 EKX52966.1 - 0.039 13.6 0.0 0.092 12.4 0.0 1.5 1 1 1 2 2 2 0 Serine hydrolase (FSH1) Ser_hydrolase PF06821.13 EKX52966.1 - 0.084 12.7 0.0 0.22 11.4 0.0 1.8 1 1 0 1 1 1 0 Serine hydrolase UPF0227 PF05728.12 EKX52966.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) WD40 PF00400.32 EKX52967.1 - 1e-62 206.6 20.6 6.8e-10 39.4 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX52967.1 - 7.3e-24 83.9 0.3 5.4e-05 23.4 0.0 6.1 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EKX52967.1 - 5.8e-16 58.2 2.9 0.0022 16.7 0.0 5.2 1 1 3 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.11 EKX52967.1 - 5.1e-14 52.6 0.2 3.8e-06 26.9 0.0 3.5 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EKX52967.1 - 4.3e-07 29.6 0.0 0.0016 17.8 0.0 3.8 1 1 3 5 5 5 1 WD40-like domain Frtz PF11768.8 EKX52967.1 - 1.8e-06 26.6 0.1 0.019 13.3 0.0 2.5 1 1 1 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 EKX52967.1 - 1e-05 24.6 0.9 1.4 7.8 0.0 4.5 1 1 4 5 5 5 2 Partner and localizer of BRCA2 WD40 domain PQQ_2 PF13360.6 EKX52967.1 - 0.0083 15.7 0.1 0.095 12.3 0.1 2.7 1 1 0 1 1 1 1 PQQ-like domain CDtoxinA PF03498.14 EKX52967.1 - 0.014 15.0 0.5 0.083 12.5 0.1 2.3 2 1 0 2 2 2 0 Cytolethal distending toxin A/C domain RicinB_lectin_2 PF14200.6 EKX52967.1 - 0.036 14.8 0.6 7.8 7.3 0.0 3.8 1 1 3 4 4 4 0 Ricin-type beta-trefoil lectin domain-like SBD PF17882.1 EKX52967.1 - 0.1 12.4 0.2 2.2 8.1 0.0 2.4 2 0 0 2 2 2 0 OAA-family lectin sugar binding domain TGBp3 PF02495.17 EKX52967.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 Triple gene block 3 Ank_2 PF12796.7 EKX52968.1 - 2.9e-13 50.2 0.0 2.1e-06 28.2 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX52968.1 - 3.3e-13 49.6 0.0 1.6e-09 37.9 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX52968.1 - 2.8e-11 42.6 0.0 0.00055 20.2 0.0 3.1 3 1 1 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EKX52968.1 - 3.6e-10 40.2 0.0 8.1e-07 29.5 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX52968.1 - 1.1e-09 38.3 0.0 0.00054 20.3 0.1 2.6 3 0 0 3 3 3 2 Ankyrin repeat Big_3 PF07523.12 EKX52968.1 - 0.17 12.2 0.0 13 6.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) CTD_bind PF04818.13 EKX52969.1 - 1.8e-18 67.1 0.1 4.7e-18 65.8 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CTK3 PF12243.8 EKX52969.1 - 0.0025 17.8 0.1 0.0052 16.8 0.1 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 DUF4968 PF16338.5 EKX52969.1 - 0.024 14.9 0.4 0.044 14.1 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4968) DUF3417 PF11897.8 EKX52969.1 - 0.071 13.6 1.1 0.15 12.6 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3417) Scramblase PF03803.15 EKX52970.1 - 3.4e-48 163.9 0.0 4.2e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Scramblase WW PF00397.26 EKX52970.1 - 7.4e-13 48.3 5.3 7.4e-13 48.3 5.3 1.7 2 0 0 2 2 2 1 WW domain PDZ_6 PF17820.1 EKX52971.1 - 3.1e-37 126.2 0.9 3.3e-09 36.4 0.0 5.7 5 0 0 5 5 5 5 PDZ domain PDZ PF00595.24 EKX52971.1 - 3.3e-37 126.7 0.1 5e-07 30.0 0.0 5.8 5 0 0 5 5 5 5 PDZ domain PDZ_2 PF13180.6 EKX52971.1 - 3e-30 104.4 6.1 3.1e-07 30.6 0.1 6.6 6 0 0 6 6 6 5 PDZ domain Tricorn_PDZ PF14685.6 EKX52971.1 - 2.4e-15 56.3 2.8 0.093 12.7 0.1 6.7 6 1 0 6 6 6 5 Tricorn protease PDZ domain RasGAP PF00616.19 EKX52971.1 - 4.7e-12 46.0 0.3 7.2e-10 38.9 0.0 3.1 3 1 1 4 4 4 2 GTPase-activator protein for Ras-like GTPase PDZ_4 PF17816.1 EKX52971.1 - 2.4e-05 24.7 0.6 16 5.9 0.0 5.7 5 0 0 5 5 5 2 PDZ domain GRASP55_65 PF04495.14 EKX52971.1 - 0.001 19.4 0.0 0.047 14.0 0.0 2.5 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain CheY-binding PF09078.11 EKX52971.1 - 0.032 14.3 0.5 0.25 11.5 0.2 2.4 2 0 0 2 2 2 0 CheY binding Fib_alpha PF08702.10 EKX52971.1 - 3 8.0 7.4 1.6 8.9 1.5 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Guanylate_kin PF00625.21 EKX52972.1 - 1.5e-60 204.0 0.0 1.7e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 EKX52972.1 - 1e-05 26.1 0.0 2e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EKX52972.1 - 6.4e-05 23.1 0.0 0.00058 20.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EKX52972.1 - 0.00018 21.5 0.0 0.00031 20.7 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 EKX52972.1 - 0.00032 20.7 0.0 0.007 16.4 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EKX52972.1 - 0.0012 19.1 0.0 0.0024 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EKX52972.1 - 0.019 14.7 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EKX52972.1 - 0.023 15.1 0.3 0.027 14.9 0.3 1.5 1 1 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 EKX52972.1 - 0.033 14.1 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_17 PF13207.6 EKX52972.1 - 0.071 13.5 0.7 0.29 11.5 0.4 2.2 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.22 EKX52972.1 - 0.13 12.7 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 EKX52972.1 - 0.17 11.8 0.2 11 6.0 0.0 2.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Use1 PF09753.9 EKX52974.1 - 8.4 6.0 16.7 2.2 8.0 13.7 1.6 1 1 0 1 1 1 0 Membrane fusion protein Use1 FH2 PF02181.23 EKX52975.1 - 9.6e-33 113.8 3.8 1.7e-12 47.2 0.0 3.6 4 0 0 4 4 4 3 Formin Homology 2 Domain BORCS6 PF10157.9 EKX52975.1 - 0.034 14.4 0.6 0.099 12.9 0.6 1.8 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 DUF4852 PF16144.5 EKX52975.1 - 0.12 12.5 0.1 0.31 11.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4852) PRIMA1 PF16101.5 EKX52975.1 - 0.22 11.5 18.4 0.36 10.9 10.2 2.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF733 PF05306.11 EKX52976.1 - 0.035 14.4 2.7 0.1 12.9 2.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF733) TPR_17 PF13431.6 EKX52977.1 - 2e-39 131.1 13.5 7.3e-05 22.9 0.5 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.6 EKX52977.1 - 1.6e-30 103.2 2.6 0.00026 21.5 0.0 8.2 1 1 8 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 EKX52977.1 - 2.4e-25 87.9 9.5 5.3e-05 22.8 0.1 7.1 5 2 2 7 7 7 5 TPR repeat TPR_19 PF14559.6 EKX52977.1 - 2e-24 85.9 5.9 0.0013 19.2 0.1 6.9 1 1 7 8 8 8 8 Tetratricopeptide repeat TPR_12 PF13424.6 EKX52977.1 - 1.2e-23 83.2 10.7 2.4e-07 30.9 0.2 7.0 1 1 6 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 EKX52977.1 - 5.2e-23 79.9 10.1 2.6e-05 23.9 0.1 8.8 9 2 0 9 9 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 EKX52977.1 - 7.2e-23 78.8 14.4 0.0033 17.4 0.2 9.1 9 1 0 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 EKX52977.1 - 1.6e-22 77.8 7.3 0.0012 18.8 0.1 9.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_10 PF13374.6 EKX52977.1 - 2e-20 72.0 20.5 0.0066 16.3 0.0 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_7 PF13176.6 EKX52977.1 - 2.7e-18 64.6 6.8 0.0046 16.9 0.0 7.2 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 EKX52977.1 - 9.5e-13 48.6 2.8 0.15 12.7 0.0 5.5 2 2 5 7 7 7 6 Tetratricopeptide repeat TPR_15 PF13429.6 EKX52977.1 - 7.3e-12 45.1 0.2 0.00012 21.4 0.1 3.2 1 1 1 3 3 3 2 Tetratricopeptide repeat Coatomer_E PF04733.14 EKX52977.1 - 2.9e-10 40.0 3.4 0.021 14.2 0.0 4.5 1 1 3 4 4 4 3 Coatomer epsilon subunit TPR_6 PF13174.6 EKX52977.1 - 2e-08 34.3 8.9 2 9.2 0.3 8.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX52977.1 - 2e-07 31.1 0.1 0.31 11.2 0.0 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat DUF4919 PF16266.5 EKX52977.1 - 2.7e-07 30.7 1.3 1.7 8.5 0.0 4.2 2 1 2 4 4 4 3 Domain of unknown function (DUF4919) 14-3-3 PF00244.20 EKX52977.1 - 7.7e-06 25.6 4.0 0.86 9.1 0.1 4.2 1 1 3 4 4 4 3 14-3-3 protein NARP1 PF12569.8 EKX52977.1 - 0.00065 18.7 1.5 0.18 10.7 0.0 3.4 1 1 3 4 4 4 1 NMDA receptor-regulated protein 1 Sel1 PF08238.12 EKX52977.1 - 0.00093 19.8 10.9 1 10.1 0.0 6.2 5 1 0 5 5 4 1 Sel1 repeat ANAPC3 PF12895.7 EKX52977.1 - 0.0021 18.2 3.2 2.8 8.2 0.2 4.4 2 2 4 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 Suf PF05843.14 EKX52977.1 - 0.0029 17.6 1.7 1.5 8.7 1.8 3.4 2 2 1 3 3 3 1 Suppressor of forked protein (Suf) Fis1_TPR_C PF14853.6 EKX52977.1 - 0.004 17.2 1.2 1.6 8.9 0.0 4.2 4 1 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.20 EKX52977.1 - 0.013 15.7 4.5 19 5.8 0.1 5.2 6 0 0 6 6 4 0 PPR repeat TPR_3 PF07720.12 EKX52977.1 - 0.07 13.2 5.5 5.2 7.2 0.0 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat MIT PF04212.18 EKX52977.1 - 0.14 12.2 8.9 6.6 6.9 0.1 5.5 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain Ank_4 PF13637.6 EKX52978.1 - 4.5e-15 55.8 1.0 1.4e-10 41.5 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX52978.1 - 2.9e-12 47.0 0.1 1.4e-11 44.8 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX52978.1 - 1.6e-08 34.1 1.4 0.0096 16.4 0.1 4.1 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 EKX52978.1 - 4.3e-07 30.1 1.7 0.015 15.7 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EKX52978.1 - 1.6e-06 28.3 1.6 3.7e-05 23.9 0.7 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) MMR_HSR1 PF01926.23 EKX52979.1 - 7.5e-15 55.0 0.0 1.1e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EKX52979.1 - 0.00069 19.6 0.0 0.0043 17.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 EKX52979.1 - 0.01 15.4 0.1 0.048 13.2 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.23 EKX52979.1 - 0.027 14.6 0.0 4.1 7.4 0.1 2.2 1 1 1 2 2 2 0 Dynamin family Roc PF08477.13 EKX52979.1 - 0.1 12.8 0.1 0.26 11.5 0.0 1.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DnaJ_C PF01556.18 EKX52980.1 - 1.8e-39 135.2 0.1 2.6e-39 134.7 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EKX52980.1 - 5.3e-24 84.1 1.9 9.1e-24 83.4 1.5 1.6 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EKX52980.1 - 4.7e-14 52.5 16.5 9.7e-14 51.5 16.5 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EKX52980.1 - 0.0018 18.2 15.3 0.05 13.6 4.1 2.6 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein FBPase_2 PF06874.11 EKX52980.1 - 0.14 10.4 0.0 0.2 9.9 0.0 1.1 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase DZR PF12773.7 EKX52980.1 - 0.21 11.6 9.3 1.3 9.1 9.3 2.2 1 1 0 1 1 1 0 Double zinc ribbon TackOD1 PF18551.1 EKX52980.1 - 7.5 6.2 6.8 4.7 6.8 1.0 2.3 1 1 0 2 2 2 0 Thaumarchaeal output domain 1 TIG PF01833.24 EKX52981.1 - 9.8e-15 54.4 0.5 1.1e-14 54.2 0.5 1.1 1 0 0 1 1 1 1 IPT/TIG domain EGF_2 PF07974.13 EKX52982.1 - 3.5e-34 116.8 185.7 1.8e-05 25.0 15.1 10.0 8 3 2 10 10 10 9 EGF-like domain EGF_Tenascin PF18720.1 EKX52982.1 - 2.8e-10 40.0 147.7 0.0021 18.1 12.9 9.7 9 0 0 9 9 9 7 Tenascin EGF domain hEGF PF12661.7 EKX52982.1 - 4.6e-07 30.2 142.2 0.019 15.6 5.7 11.8 11 0 0 11 11 11 7 Human growth factor-like EGF EGF PF00008.27 EKX52982.1 - 0.0006 20.1 162.9 0.027 14.8 6.9 10.5 10 1 0 10 10 10 7 EGF-like domain Laminin_EGF PF00053.24 EKX52982.1 - 0.039 14.1 10.1 0.039 14.1 10.1 10.2 3 3 6 10 10 10 0 Laminin EGF domain FYVE PF01363.21 EKX52983.1 - 5.1e-05 23.3 0.0 0.0036 17.4 0.3 2.6 2 1 0 2 2 2 1 FYVE zinc finger DUF3818 PF12825.7 EKX52983.1 - 0.62 9.0 2.9 1.1 8.2 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) zf-C2HC_2 PF13913.6 EKX52983.1 - 0.63 10.0 3.0 0.47 10.4 0.1 2.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Guanylate_kin PF00625.21 EKX52984.1 - 9.7e-60 201.4 0.1 3e-59 199.8 0.0 1.8 2 0 0 2 2 2 1 Guanylate kinase ADK PF00406.22 EKX52984.1 - 1.6e-25 90.0 3.9 2.8e-16 59.9 0.0 4.3 3 1 1 4 4 4 2 Adenylate kinase AAA_17 PF13207.6 EKX52984.1 - 6.7e-19 68.7 10.3 1.2e-08 35.5 0.0 4.7 4 1 1 5 5 4 3 AAA domain AAA_18 PF13238.6 EKX52984.1 - 1.7e-12 48.0 3.4 1.7e-06 28.6 0.0 3.8 2 2 2 4 4 4 2 AAA domain Zeta_toxin PF06414.12 EKX52984.1 - 2.6e-08 33.4 0.2 0.0064 15.8 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_33 PF13671.6 EKX52984.1 - 7.3e-07 29.4 1.1 0.29 11.3 0.0 4.1 2 2 1 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EKX52984.1 - 1.8e-05 24.7 0.2 0.00034 20.6 0.0 2.6 3 0 0 3 3 3 1 RsgA GTPase AAA_19 PF13245.6 EKX52984.1 - 2.3e-05 24.8 0.3 0.005 17.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EKX52984.1 - 0.00012 22.5 1.1 0.0065 16.9 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.15 EKX52984.1 - 0.00039 20.4 0.6 0.04 13.8 0.0 2.5 2 0 0 2 2 2 1 NTPase AAA_22 PF13401.6 EKX52984.1 - 0.00043 20.6 0.6 0.046 14.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EKX52984.1 - 0.00071 20.1 0.0 1.7 9.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter Rad17 PF03215.15 EKX52984.1 - 0.0047 16.9 0.0 0.17 11.8 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA PF00004.29 EKX52984.1 - 0.005 17.3 0.4 3.7 8.0 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EKX52984.1 - 0.0064 16.2 0.1 4.4 7.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EKX52984.1 - 0.0075 16.0 0.1 0.16 11.7 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EKX52984.1 - 0.012 15.7 0.1 1.1 9.3 0.0 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase NB-ARC PF00931.22 EKX52984.1 - 0.012 14.8 1.0 2.2 7.4 0.0 2.6 2 1 0 2 2 2 0 NB-ARC domain MeaB PF03308.16 EKX52984.1 - 0.018 14.0 0.4 5.3 5.9 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Sigma54_activ_2 PF14532.6 EKX52984.1 - 0.019 15.1 0.0 0.14 12.3 0.0 2.4 2 1 1 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.22 EKX52984.1 - 0.021 15.2 0.0 0.76 10.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 EKX52984.1 - 0.034 14.4 0.1 4.1 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 EKX52984.1 - 0.04 13.6 0.0 3.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 EKX52984.1 - 0.042 13.6 1.3 1.5 8.5 0.1 2.5 3 0 0 3 3 2 0 AAA domain T2SSE PF00437.20 EKX52984.1 - 0.043 12.9 0.0 6.8 5.7 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein SRP54 PF00448.22 EKX52984.1 - 0.048 13.3 0.1 5.6 6.5 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NACHT PF05729.12 EKX52984.1 - 0.082 12.8 1.4 1.8 8.5 0.0 2.6 2 1 0 2 2 2 0 NACHT domain Tup_N PF08581.10 EKX52986.1 - 0.056 13.8 0.7 3.6 7.9 0.1 2.9 1 1 1 2 2 2 0 Tup N-terminal FlgM PF04316.13 EKX52986.1 - 0.064 13.6 0.4 0.78 10.2 0.0 2.6 3 0 0 3 3 3 0 Anti-sigma-28 factor, FlgM SAMP PF05924.11 EKX52986.1 - 0.14 11.5 0.2 0.3 10.4 0.2 1.6 1 0 0 1 1 1 0 SAMP Motif Tropomyosin PF00261.20 EKX52986.1 - 0.73 9.2 10.4 0.033 13.6 4.8 1.6 2 0 0 2 2 2 0 Tropomyosin CH PF00307.31 EKX52987.1 - 1.2e-21 77.0 1.9 8.2e-05 22.7 0.0 4.6 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EKX52987.1 - 9.1e-06 25.4 0.0 1.2 9.1 0.0 4.1 3 1 0 3 3 3 3 CAMSAP CH domain Cyt_bd_oxida_II PF02322.15 EKX52987.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II Peptidase_S11 PF00768.20 EKX52988.1 - 1.4e-25 90.1 0.1 7.3e-16 58.3 0.1 3.1 2 1 1 3 3 3 3 D-alanyl-D-alanine carboxypeptidase RCC1 PF00415.18 EKX52989.1 - 2.6e-31 108.0 11.7 1.1e-12 48.4 0.0 5.0 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX52989.1 - 8.4e-26 89.2 18.9 3.5e-07 29.8 0.0 4.3 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 EKX52989.1 - 0.088 13.3 0.0 0.26 11.7 0.0 1.6 1 1 0 1 1 1 0 SUKH-3 immunity protein DUF4505 PF14956.6 EKX52989.1 - 0.26 11.0 0.0 0.62 9.8 0.0 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4505) Ank_4 PF13637.6 EKX52991.1 - 0.0019 18.7 0.0 0.0028 18.2 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Complex1_LYR PF05347.15 EKX52991.1 - 0.057 13.5 1.1 1.7 8.8 0.3 2.3 2 0 0 2 2 2 0 Complex 1 protein (LYR family) DUF4748 PF15932.5 EKX52991.1 - 0.064 13.0 1.6 0.11 12.2 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) Ank_2 PF12796.7 EKX52991.1 - 0.094 13.3 0.0 0.14 12.8 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Vps39_1 PF10366.9 EKX52991.1 - 0.12 12.7 0.1 0.19 12.0 0.1 1.4 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 zf-RING_2 PF13639.6 EKX52993.1 - 7.5e-14 51.8 6.1 8.3e-14 51.6 6.1 1.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EKX52993.1 - 2.5e-11 43.1 3.8 4.1e-11 42.4 3.8 1.3 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EKX52993.1 - 4.5e-11 42.4 5.3 5.4e-11 42.2 5.3 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX52993.1 - 1.7e-09 37.4 5.3 2e-09 37.2 5.3 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EKX52993.1 - 3.9e-09 36.2 3.3 4.5e-09 36.0 3.3 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX52993.1 - 5.3e-09 36.2 9.1 3.4e-08 33.7 9.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EKX52993.1 - 6.9e-07 29.2 3.1 1e-06 28.6 3.1 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EKX52993.1 - 2.3e-06 27.4 4.1 3e-06 27.1 4.1 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EKX52993.1 - 1.3e-05 25.2 4.3 2.5e-05 24.2 4.3 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EKX52993.1 - 1.7e-05 24.5 5.4 2.3e-05 24.2 5.4 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EKX52993.1 - 9.3e-05 22.0 3.9 0.00013 21.5 3.8 1.3 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 EKX52993.1 - 0.00024 21.3 3.7 0.0003 21.0 3.7 1.1 1 0 0 1 1 1 1 RING-like domain FANCL_C PF11793.8 EKX52993.1 - 0.00065 19.8 8.4 0.082 13.1 8.4 2.4 1 1 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.7 EKX52993.1 - 0.0037 17.3 3.8 0.0099 16.0 3.8 1.7 1 1 0 1 1 1 1 RING-variant domain Vps39_2 PF10367.9 EKX52993.1 - 0.032 14.7 1.3 1.4 9.4 0.3 2.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-RING_4 PF14570.6 EKX52993.1 - 0.035 13.9 4.2 0.074 12.8 4.2 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_RING PF05883.11 EKX52993.1 - 0.044 13.8 0.8 0.072 13.1 0.8 1.3 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain PHD PF00628.29 EKX52993.1 - 0.052 13.4 3.3 0.1 12.5 3.3 1.5 1 1 0 1 1 1 0 PHD-finger Coronavirus_5 PF05528.11 EKX52993.1 - 0.096 12.7 1.2 0.22 11.5 0.2 1.8 1 1 1 2 2 2 0 Coronavirus gene 5 protein C1_1 PF00130.22 EKX52993.1 - 0.11 12.4 5.6 1.3 8.9 1.9 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-Nse PF11789.8 EKX52993.1 - 0.13 12.1 2.0 0.15 11.9 2.0 1.2 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 EKX52993.1 - 0.7 10.1 6.9 4.8 7.4 6.9 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING LRR_6 PF13516.6 EKX52994.1 - 4.2e-20 70.0 19.6 2.9e-05 23.8 0.0 7.1 7 0 0 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.33 EKX52994.1 - 3.6e-12 45.0 17.6 0.34 11.6 0.2 7.0 7 0 0 7 7 7 5 Leucine Rich Repeat LRR_4 PF12799.7 EKX52994.1 - 1.2e-07 32.0 13.4 0.32 11.5 0.1 4.7 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX52994.1 - 0.0014 18.3 19.5 2.2 8.1 4.8 5.6 4 2 0 4 4 4 3 Leucine rich repeat Ank_2 PF12796.7 EKX52995.1 - 0.00019 22.0 0.0 0.00087 19.8 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX52995.1 - 0.0036 17.7 0.0 4.5 8.2 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EKX52995.1 - 0.0039 17.7 0.1 0.017 15.7 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DMA PF03474.14 EKX52995.1 - 0.12 12.0 0.5 0.27 10.8 0.1 1.9 2 1 0 2 2 2 0 DMRTA motif Mito_carr PF00153.27 EKX52996.1 - 1.2e-40 137.4 3.4 2.9e-20 72.0 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein RSB_motif PF16294.5 EKX52997.1 - 0.00082 19.6 5.9 0.0015 18.8 0.1 2.3 2 0 0 2 2 2 1 RNSP1-SAP18 binding (RSB) motif RRM_1 PF00076.22 EKX52997.1 - 0.011 15.5 0.0 1 9.2 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dcc1 PF09724.9 EKX52998.1 - 1.3e-58 198.9 2.6 1.6e-58 198.6 2.6 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 HMG_box PF00505.19 EKX52999.1 - 1.4e-27 95.9 9.5 4.5e-23 81.4 4.8 3.9 3 1 1 4 4 4 3 HMG (high mobility group) box HMG_box_2 PF09011.10 EKX52999.1 - 2.2e-14 53.8 4.5 2.2e-14 53.8 4.5 4.0 3 1 0 3 3 3 1 HMG-box domain CHDNT PF08073.12 EKX52999.1 - 2.1e-05 24.4 0.1 0.00052 19.9 0.0 2.3 2 0 0 2 2 2 1 CHDNT (NUC034) domain DUF4407 PF14362.6 EKX52999.1 - 3.9 6.7 12.4 0.77 9.0 8.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Redoxin PF08534.10 EKX53000.1 - 1.1e-30 106.3 0.0 4.4e-30 104.3 0.0 1.8 2 0 0 2 2 2 1 Redoxin Glutaredoxin PF00462.24 EKX53000.1 - 1.5e-13 50.7 0.0 3.1e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin AhpC-TSA PF00578.21 EKX53000.1 - 7.8e-13 48.4 0.0 5e-12 45.8 0.0 2.0 2 0 0 2 2 2 1 AhpC/TSA family DUF836 PF05768.14 EKX53000.1 - 0.0036 17.7 0.0 0.0067 16.8 0.0 1.6 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) TraF PF13728.6 EKX53000.1 - 0.022 14.6 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 EKX53000.1 - 0.036 14.1 0.0 0.44 10.6 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin domain FAM163 PF15069.6 EKX53000.1 - 0.14 12.6 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 FAM163 family IQ PF00612.27 EKX53001.1 - 0.0001 21.8 27.9 0.002 17.8 1.0 5.8 5 0 0 5 5 5 3 IQ calmodulin-binding motif PDZ PF00595.24 EKX53002.1 - 2e-11 44.1 0.2 0.00033 20.9 0.1 2.4 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EKX53002.1 - 3.8e-11 42.6 1.1 1.3e-05 24.9 0.1 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX53002.1 - 1.3e-06 28.7 0.1 0.012 15.9 0.0 2.8 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 EKX53002.1 - 0.15 12.0 0.1 2.5 8.1 0.0 2.4 2 0 0 2 2 2 0 Tricorn protease PDZ domain Rho_Binding PF08912.11 EKX53002.1 - 3 8.7 13.4 9.9 7.1 0.2 2.9 2 0 0 2 2 2 0 Rho Binding Arm PF00514.23 EKX53003.1 - 0.033 14.2 1.1 6.5 6.9 0.0 2.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Mito_carr PF00153.27 EKX53004.1 - 5.5e-48 160.9 8.4 2.5e-17 62.5 0.0 3.6 4 0 0 4 4 4 3 Mitochondrial carrier protein GMC_oxred_N PF00732.19 EKX53005.1 - 0.028 13.8 0.1 0.032 13.6 0.1 1.1 1 0 0 1 1 1 0 GMC oxidoreductase ABC_membrane PF00664.23 EKX53006.1 - 1.2e-32 113.7 15.1 3.8e-23 82.5 5.3 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 EKX53006.1 - 7.9e-30 104.2 2.8 8.3e-20 71.7 0.1 2.7 2 0 0 2 2 2 2 ABC transporter T2SSE PF00437.20 EKX53006.1 - 3.8e-06 26.2 1.1 0.00035 19.7 0.1 2.5 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_29 PF13555.6 EKX53006.1 - 5.8e-06 26.0 0.9 0.094 12.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EKX53006.1 - 1.8e-05 25.2 3.7 0.0025 18.2 0.3 3.2 2 1 1 3 3 2 1 AAA ATPase domain SMC_N PF02463.19 EKX53006.1 - 1.8e-05 24.3 5.9 0.031 13.7 0.9 3.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EKX53006.1 - 2.5e-05 24.2 5.1 0.00027 20.9 1.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 EKX53006.1 - 5.7e-05 23.1 0.6 0.32 10.8 0.0 3.4 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EKX53006.1 - 9.5e-05 22.5 3.8 0.26 11.4 0.2 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_30 PF13604.6 EKX53006.1 - 0.0022 17.8 0.1 2.5 7.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 EKX53006.1 - 0.0025 17.0 0.6 0.22 10.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 EKX53006.1 - 0.0039 16.8 0.1 0.24 11.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EKX53006.1 - 0.0049 16.4 0.3 0.62 9.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 EKX53006.1 - 0.013 15.8 0.8 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EKX53006.1 - 0.023 13.9 0.6 1.1 8.4 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 EKX53006.1 - 0.034 14.0 3.3 0.2 11.6 0.1 2.8 3 0 0 3 3 3 0 NACHT domain IstB_IS21 PF01695.17 EKX53006.1 - 0.036 13.8 1.5 11 5.7 0.0 3.1 4 0 0 4 4 3 0 IstB-like ATP binding protein MeaB PF03308.16 EKX53006.1 - 0.068 12.1 1.1 6.9 5.6 0.1 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 EKX53006.1 - 0.072 13.0 2.6 1.3 8.9 0.1 2.9 3 0 0 3 3 3 0 NTPase RNA_helicase PF00910.22 EKX53006.1 - 0.074 13.5 0.6 2.3 8.7 0.1 2.7 2 0 0 2 2 2 0 RNA helicase KAP_NTPase PF07693.14 EKX53006.1 - 0.076 12.2 1.0 1 8.5 0.0 2.7 2 1 0 2 2 2 0 KAP family P-loop domain FtsK_SpoIIIE PF01580.18 EKX53006.1 - 0.077 12.3 0.2 2.3 7.5 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 EKX53006.1 - 0.1 11.9 0.7 0.52 9.6 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 EKX53006.1 - 0.13 12.2 1.1 0.61 10.1 0.0 2.5 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP-synt_ab PF00006.25 EKX53006.1 - 0.14 11.7 0.1 6.2 6.4 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.19 EKX53006.1 - 0.22 11.1 5.1 1.8 8.1 0.2 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 EKX53006.1 - 0.25 11.1 0.9 3.1 7.4 0.1 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 EKX53006.1 - 0.59 10.7 5.2 3 8.4 0.0 3.0 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.17 EKX53006.1 - 2.9 7.9 9.3 0.66 10.0 0.4 2.8 2 1 1 3 3 3 0 Helicase HerA, central domain DUF2052 PF09747.9 EKX53006.1 - 3 7.9 14.5 2.1 8.5 7.3 2.5 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) CDC45 PF02724.14 EKX53006.1 - 4.6 5.4 11.6 5.9 5.0 0.5 2.1 2 0 0 2 2 2 0 CDC45-like protein PTPRCAP PF15713.5 EKX53006.1 - 6.3 7.1 18.2 0.12 12.7 5.3 2.6 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated TPR_17 PF13431.6 EKX53007.1 - 0.00011 22.4 0.0 0.051 14.0 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX53007.1 - 0.00031 21.3 0.0 0.019 15.7 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX53007.1 - 0.00066 19.3 0.0 0.021 14.5 0.0 2.2 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 EKX53007.1 - 0.00097 19.7 0.0 0.0014 19.3 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX53007.1 - 0.00098 19.1 0.0 0.93 9.8 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX53007.1 - 0.011 15.5 0.0 0.78 9.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX53007.1 - 0.064 13.8 0.0 0.52 10.9 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3509 PF12021.8 EKX53007.1 - 0.068 12.9 0.4 5.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3509) TPR_15 PF13429.6 EKX53007.1 - 0.097 11.9 0.0 0.55 9.4 0.0 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat Glyco_transf_41 PF13844.6 EKX53008.1 - 8.5e-59 199.2 0.0 9.7e-34 116.6 0.0 2.0 1 1 1 2 2 2 2 Glycosyl transferase family 41 DAGAT PF03982.13 EKX53009.1 - 3.1e-05 23.1 0.1 3.8e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Kelch_1 PF01344.25 EKX53010.1 - 6e-52 173.0 9.2 1.7e-11 43.5 0.3 5.1 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 EKX53010.1 - 1.4e-33 114.0 0.6 7.1e-08 32.5 0.0 5.0 1 1 4 5 5 5 5 Kelch motif Kelch_3 PF13415.6 EKX53010.1 - 2.2e-24 85.2 0.8 4.1e-06 26.9 0.0 5.0 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_4 PF13418.6 EKX53010.1 - 2e-20 72.5 0.3 0.00018 21.4 0.0 5.1 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_2 PF07646.15 EKX53010.1 - 6.6e-19 67.1 1.6 0.007 16.3 0.0 5.1 5 0 0 5 5 5 5 Kelch motif Kelch_5 PF13854.6 EKX53010.1 - 1.1e-14 54.0 6.1 0.011 15.8 0.0 5.3 5 1 0 5 5 5 5 Kelch motif PPR_2 PF13041.6 EKX53011.1 - 2.4e-57 190.9 3.9 6.5e-08 32.7 0.3 9.5 9 1 0 9 9 9 9 PPR repeat family PPR_3 PF13812.6 EKX53011.1 - 3.5e-39 132.7 0.0 1.3e-09 38.0 0.0 7.4 5 1 1 7 7 7 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 EKX53011.1 - 7.1e-23 80.0 14.5 0.00019 21.1 0.3 10.1 12 0 0 12 12 12 6 PPR repeat PPR_long PF17177.4 EKX53011.1 - 9.3e-23 80.7 9.4 5.4e-11 42.3 0.2 5.5 3 2 2 5 5 5 5 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EKX53011.1 - 1.4e-15 56.4 31.3 0.012 15.8 0.0 12.7 13 1 0 13 13 13 5 PPR repeat MRP-S27 PF10037.9 EKX53011.1 - 0.084 11.7 0.0 0.28 10.0 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 Arv1 PF04161.13 EKX53012.1 - 6.6e-30 104.8 2.3 7.2e-30 104.7 2.3 1.0 1 0 0 1 1 1 1 Arv1-like family DZR PF12773.7 EKX53012.1 - 0.017 15.1 1.4 0.023 14.7 1.4 1.2 1 0 0 1 1 1 0 Double zinc ribbon LMWPc PF01451.21 EKX53013.1 - 2.2e-05 24.8 0.0 0.00036 20.9 0.0 2.1 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase TMEM131_like PF12371.8 EKX53014.1 - 8.3e-13 48.4 6.9 1.1e-11 44.8 0.1 5.3 6 0 0 6 6 6 1 Transmembrane protein 131-like ASH PF15780.5 EKX53014.1 - 7.8e-07 29.2 2.9 0.31 11.3 0.0 6.5 6 0 0 6 6 6 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 EKX53014.1 - 1.4e-06 28.2 3.6 0.00052 20.0 0.1 5.3 5 0 0 5 5 5 1 Protein of unknown function (DUF1573) PSII_BNR PF14870.6 EKX53015.1 - 1.3e-10 41.1 0.1 3.2e-06 26.6 0.0 2.3 2 0 0 2 2 2 2 Photosynthesis system II assembly factor YCF48 Sortilin-Vps10 PF15902.5 EKX53015.1 - 0.012 14.5 0.0 0.49 9.1 0.0 2.2 2 0 0 2 2 2 0 Sortilin, neurotensin receptor 3, BNR PF02012.20 EKX53015.1 - 0.068 13.2 2.5 3.5 8.0 0.0 3.6 3 0 0 3 3 3 0 BNR/Asp-box repeat TrmE_N PF10396.9 EKX53015.1 - 0.072 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 GTP-binding protein TrmE N-terminus Ins145_P3_rec PF08709.11 EKX53016.1 - 6.9e-19 67.9 0.1 4.7e-15 55.3 0.0 2.5 1 1 1 2 2 2 2 Inositol 1,4,5-trisphosphate/ryanodine receptor RYDR_ITPR PF01365.21 EKX53016.1 - 2.7e-10 40.0 13.2 1.2e-06 28.1 9.4 3.0 2 0 0 2 2 2 2 RIH domain RIH_assoc PF08454.11 EKX53016.1 - 4.5e-10 39.3 0.3 4.5e-10 39.3 0.3 3.7 2 0 0 2 2 2 1 RyR and IP3R Homology associated MIR PF02815.19 EKX53016.1 - 3.9e-09 36.6 0.1 3.1e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 MIR domain Ion_trans PF00520.31 EKX53016.1 - 0.00011 21.6 3.8 0.00011 21.6 3.8 3.4 4 0 0 4 4 4 1 Ion transport protein IGFL PF14653.6 EKX53016.1 - 0.028 14.4 1.8 0.084 12.9 1.8 1.7 1 0 0 1 1 1 0 Insulin growth factor-like family TMF_TATA_bd PF12325.8 EKX53017.1 - 0.00039 20.6 1.9 0.00039 20.6 1.9 9.7 1 1 8 9 9 9 1 TATA element modulatory factor 1 TATA binding HAUS-augmin3 PF14932.6 EKX53017.1 - 0.0036 16.9 15.7 0.0036 16.9 15.7 7.0 1 1 6 7 7 7 1 HAUS augmin-like complex subunit 3 DUF4472 PF14739.6 EKX53017.1 - 0.016 15.9 7.3 0.016 15.9 7.3 8.6 1 1 9 10 10 10 0 Domain of unknown function (DUF4472) MUG113 PF13455.6 EKX53017.1 - 0.035 14.8 1.0 0.44 11.3 1.0 3.0 1 0 0 1 1 1 0 Meiotically up-regulated gene 113 DASH_Dam1 PF08653.10 EKX53017.1 - 2.6 7.9 5.9 4.4 7.2 0.9 4.2 3 0 0 3 3 3 0 DASH complex subunit Dam1 UPF0640 PF15114.6 EKX53018.1 - 0.01 15.6 1.7 0.015 15.1 1.4 1.6 1 1 0 1 1 1 0 Uncharacterised protein family UPF0640 VGCC_beta4Aa_N PF12052.8 EKX53018.1 - 4.8 7.4 12.8 1.8 8.7 6.1 2.1 1 1 1 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal HTH_psq PF05225.16 EKX53019.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 helix-turn-helix, Psq domain MTHFR PF02219.17 EKX53021.1 - 2.1e-72 243.9 0.0 2.8e-72 243.5 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Amidase PF01425.21 EKX53023.1 - 3.1e-71 240.7 0.5 2.7e-67 227.7 0.8 2.0 1 1 0 2 2 2 2 Amidase EamA PF00892.20 EKX53024.1 - 6e-26 91.3 21.0 2e-14 53.9 3.7 2.0 2 0 0 2 2 2 2 EamA-like transporter family DUF5493 PF17597.2 EKX53024.1 - 0.0025 18.1 1.2 2.2 8.6 0.1 3.0 3 0 0 3 3 3 2 Family of unknown function (DUF5493) TPT PF03151.16 EKX53024.1 - 0.038 13.4 1.5 0.043 13.1 0.2 1.6 2 0 0 2 2 2 0 Triose-phosphate Transporter family PipA PF07108.11 EKX53025.1 - 0.00023 20.8 0.4 0.0005 19.6 0.1 1.7 2 0 0 2 2 2 1 PipA protein DDE_Tnp_1_2 PF13586.6 EKX53025.1 - 0.048 14.0 1.2 0.083 13.3 1.1 1.5 1 1 0 1 1 1 0 Transposase DDE domain DUF5595 PF18077.1 EKX53026.1 - 0.22 11.6 0.5 0.5 10.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) Endonuclease_7 PF02945.15 EKX53026.1 - 1.7 8.7 4.5 0.37 10.8 0.3 2.2 3 0 0 3 3 3 0 Recombination endonuclease VII ASFV_J13L PF05568.11 EKX53027.1 - 0.23 11.2 1.2 1.6 8.5 0.1 1.9 1 1 1 2 2 2 0 African swine fever virus J13L protein CarbpepA_inh PF02977.15 EKX53028.1 - 0.47 10.3 5.3 0.76 9.6 1.3 2.6 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor DUF1293 PF06950.11 EKX53029.1 - 0.014 15.5 0.4 0.13 12.4 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1293) DUF4393 PF14337.6 EKX53029.1 - 0.5 10.1 10.3 0.027 14.3 4.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4393) UTP15_C PF09384.10 EKX53031.1 - 0.035 13.8 0.2 9.5 5.9 0.0 2.7 3 0 0 3 3 3 0 UTP15 C terminal DUF3673 PF12425.8 EKX53032.1 - 0.021 14.7 0.2 0.067 13.1 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3673) Histone PF00125.24 EKX53033.1 - 0.004 17.5 2.3 0.28 11.5 0.2 2.6 2 0 0 2 2 2 2 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EKX53033.1 - 0.017 15.4 0.6 0.1 12.9 0.1 2.6 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PDT PF00800.18 EKX53033.1 - 0.019 14.7 0.5 0.17 11.7 0.1 2.2 2 0 0 2 2 2 0 Prephenate dehydratase CYTL1 PF15153.6 EKX53033.1 - 0.027 14.4 0.4 0.083 12.8 0.1 2.0 2 1 0 2 2 2 0 Cytokine-like protein 1 OrfB_Zn_ribbon PF07282.11 EKX53034.1 - 8.7e-07 28.8 2.0 2.9e-06 27.1 2.0 1.9 1 0 0 1 1 1 1 Putative transposase DNA-binding domain NMD3 PF04981.13 EKX53038.1 - 6.8e-38 130.5 12.4 3.6e-20 72.5 0.1 2.2 1 1 1 2 2 2 2 NMD3 family zf-3CxxC PF13695.6 EKX53038.1 - 0.28 11.7 5.5 0.53 10.8 5.5 1.5 1 0 0 1 1 1 0 Zinc-binding domain zf-UBR PF02207.20 EKX53038.1 - 2.7 8.2 7.4 0.54 10.5 2.6 2.3 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) DZR PF12773.7 EKX53038.1 - 2.7 8.1 8.8 15 5.7 8.8 2.2 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 EKX53038.1 - 8.3 6.5 7.4 1.3 9.1 2.1 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NAD_binding_10 PF13460.6 EKX53039.1 - 1.6e-16 60.7 0.0 2.8e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EKX53039.1 - 3.6e-08 32.7 0.0 5.7e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TPR_1 PF00515.28 EKX53040.1 - 8.5e-18 63.4 0.2 7.3e-11 41.4 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX53040.1 - 2.7e-11 42.7 0.1 1.5e-05 24.7 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX53040.1 - 3.1e-09 36.3 0.8 0.00012 22.0 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX53040.1 - 1.3e-07 31.5 0.0 0.02 15.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX53040.1 - 6.1e-06 26.4 0.0 0.0088 16.3 0.0 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX53040.1 - 0.00017 21.2 0.1 0.25 11.1 0.0 2.9 3 1 0 3 3 3 2 TPR repeat TPR_15 PF13429.6 EKX53040.1 - 0.00068 18.9 0.0 0.8 8.9 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX53040.1 - 0.0063 16.7 0.3 0.009 16.2 0.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EKX53040.1 - 0.013 16.3 0.0 3.4 8.7 0.0 2.6 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX53040.1 - 0.013 16.0 0.0 0.36 11.4 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX53040.1 - 0.023 15.3 0.0 12 6.7 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF753 PF05444.12 EKX53040.1 - 0.062 13.3 0.4 0.099 12.6 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF753) TPR_7 PF13176.6 EKX53040.1 - 0.086 12.9 0.1 0.47 10.6 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 EKX53041.1 - 3.6e-33 115.1 0.0 4.6e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX53041.1 - 1.2e-22 80.4 0.0 1.6e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EKX53041.1 - 0.012 15.2 0.0 0.018 14.6 0.0 1.3 1 1 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 EKX53041.1 - 0.033 13.5 0.0 0.28 10.4 0.0 2.0 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 EKX53041.1 - 0.098 12.3 0.0 11 5.6 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Mlh1_C PF16413.5 EKX53042.1 - 3.7e-84 282.3 0.1 8.8e-84 281.1 0.0 1.7 2 0 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 EKX53042.1 - 2.7e-25 88.4 0.2 2.1e-24 85.5 0.2 2.3 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EKX53042.1 - 8.4e-15 54.8 0.1 1.8e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EKX53042.1 - 1.5e-07 31.9 0.0 4e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MCR_C PF04609.12 EKX53042.1 - 0.056 12.5 0.2 3.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Methyl-coenzyme M reductase operon protein C Mg_trans_NIPA PF05653.14 EKX53044.1 - 1.5e-53 181.9 16.2 1.8e-53 181.6 16.2 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EKX53044.1 - 5.9e-08 33.0 2.9 5.9e-08 33.0 2.9 3.1 3 1 0 3 3 3 1 EamA-like transporter family TMEM234 PF10639.9 EKX53044.1 - 0.0014 18.6 0.2 0.0038 17.3 0.2 1.8 1 0 0 1 1 1 1 Putative transmembrane family 234 CoA_binding_3 PF13727.6 EKX53044.1 - 0.0016 18.5 5.7 0.52 10.3 1.5 2.6 1 1 0 2 2 2 2 CoA-binding domain UAA PF08449.11 EKX53044.1 - 0.025 13.8 9.1 0.016 14.4 6.2 2.1 1 1 0 2 2 2 0 UAA transporter family E1-E2_ATPase PF00122.20 EKX53044.1 - 6.2 6.3 6.1 2.2 7.8 0.3 2.5 1 1 0 2 2 2 0 E1-E2 ATPase EF-hand_7 PF13499.6 EKX53045.1 - 1.5e-06 28.5 0.2 5.2e-06 26.8 0.2 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX53045.1 - 2.9e-06 26.4 0.0 0.027 14.0 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX53045.1 - 4.1e-05 23.2 0.0 0.083 12.9 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EKX53045.1 - 0.00073 19.3 0.4 0.0016 18.2 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX53045.1 - 0.00099 18.5 1.3 1.5 8.4 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 EKX53045.1 - 0.022 15.1 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain Dockerin_1 PF00404.18 EKX53045.1 - 0.12 12.6 0.1 0.21 11.8 0.1 1.3 1 0 0 1 1 1 0 Dockerin type I domain GAIN_A PF18619.1 EKX53046.1 - 0.01 16.0 0.2 0.025 14.8 0.2 1.7 1 0 0 1 1 1 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A DUF2890 PF11081.8 EKX53046.1 - 0.011 15.8 0.2 0.024 14.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) LON_substr_bdg PF02190.16 EKX53048.1 - 6.9e-13 48.9 0.1 8.4e-13 48.7 0.1 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain MRP-L27 PF09809.9 EKX53049.1 - 7.5e-23 80.5 0.1 9.6e-23 80.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Pkinase PF00069.25 EKX53050.1 - 4.9e-46 157.2 0.0 6.1e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX53050.1 - 1.5e-28 99.8 0.0 1.8e-28 99.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX53050.1 - 0.0003 20.2 0.0 0.00043 19.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EKX53050.1 - 0.012 15.5 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ank_4 PF13637.6 EKX53051.1 - 2.3e-22 79.1 0.4 2.2e-11 44.0 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX53051.1 - 6.7e-17 61.3 0.2 2.2e-11 43.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX53051.1 - 9.5e-16 58.2 0.0 1.1e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX53051.1 - 2e-13 50.1 0.0 8.9e-08 32.2 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EKX53051.1 - 2e-13 49.2 0.0 1.9e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat DUF1843 PF08898.10 EKX53051.1 - 0.079 13.5 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) UBX PF00789.20 EKX53052.1 - 2.7e-09 37.1 0.0 7.9e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 UBX domain UVR PF02151.19 EKX53052.1 - 1.1e-07 31.3 5.5 1.1e-07 31.3 5.5 2.9 3 0 0 3 3 3 1 UvrB/uvrC motif PDZ_6 PF17820.1 EKX53053.1 - 0.0016 18.2 0.2 0.011 15.5 0.0 2.4 3 0 0 3 3 3 1 PDZ domain PDZ_2 PF13180.6 EKX53053.1 - 0.0079 16.5 0.0 0.036 14.4 0.0 2.2 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX53053.1 - 0.03 14.7 0.0 0.082 13.3 0.0 1.8 1 0 0 1 1 1 0 PDZ domain tRNA-synt_1b PF00579.25 EKX53054.1 - 9.9e-19 67.7 0.0 2.2e-18 66.6 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Methyltransf_25 PF13649.6 EKX53055.1 - 8.7e-05 23.2 0.0 0.0002 22.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX53055.1 - 0.11 13.2 0.2 0.41 11.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain DUF1722 PF08349.11 EKX53055.1 - 0.16 12.2 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) PBP PF01161.20 EKX53057.1 - 0.094 13.0 0.1 22 5.4 0.0 2.3 2 0 0 2 2 2 0 Phosphatidylethanolamine-binding protein Imm58 PF15581.6 EKX53057.1 - 0.1 12.7 0.0 3.1 7.9 0.0 2.1 2 0 0 2 2 2 0 Immunity protein 58 RsfS PF02410.15 EKX53058.1 - 5.5e-19 68.4 0.1 8.3e-19 67.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation DUF4201 PF13870.6 EKX53059.1 - 7.8 6.2 55.3 0.025 14.3 10.6 4.3 4 2 0 4 4 4 0 Domain of unknown function (DUF4201) Thymidylate_kin PF02223.17 EKX53061.1 - 1e-44 152.4 0.0 1.2e-44 152.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.10 EKX53061.1 - 0.0015 18.0 0.3 0.023 14.2 0.3 2.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 EKX53061.1 - 0.011 16.3 0.1 0.035 14.7 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 EKX53061.1 - 0.021 15.0 0.0 0.069 13.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain Ntox14 PF15522.6 EKX53061.1 - 0.11 11.9 0.1 0.5 9.8 0.0 1.9 1 1 0 2 2 2 0 Novel toxin 14 dNK PF01712.19 EKX53061.1 - 0.15 11.9 0.1 1.2 9.0 0.1 2.2 1 1 0 1 1 1 0 Deoxynucleoside kinase Response_reg PF00072.24 EKX53062.1 - 1.8e-23 82.8 0.1 6.3e-23 81.1 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 EKX53062.1 - 2e-16 60.5 0.0 4.2e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EKX53062.1 - 8.7e-07 28.9 0.4 3.6e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF PF01590.26 EKX53062.1 - 0.00054 20.6 0.0 0.0011 19.6 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 EKX53062.1 - 0.09 13.1 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 GAF domain CENP-F_leu_zip PF10473.9 EKX53063.1 - 0.024 14.7 6.3 0.043 13.8 6.3 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nup54 PF13874.6 EKX53063.1 - 0.078 13.1 2.8 0.11 12.6 2.8 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Herpes_UL14 PF03580.14 EKX53063.1 - 0.16 12.2 3.8 0.91 9.8 0.7 2.0 1 1 1 2 2 2 0 Herpesvirus UL14-like protein GrpE PF01025.19 EKX53063.1 - 0.48 10.1 5.5 0.83 9.3 5.5 1.6 1 1 0 1 1 1 0 GrpE PDZ_6 PF17820.1 EKX53064.1 - 9.2e-07 28.6 0.0 1.8e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX53064.1 - 0.0002 21.6 0.0 0.00038 20.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX53064.1 - 0.015 15.6 0.0 0.033 14.5 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Tricorn_PDZ PF14685.6 EKX53064.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Tricorn protease PDZ domain Ribophorin_II PF05817.14 EKX53064.1 - 2 6.9 3.2 2.6 6.5 3.2 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II FKBP_C PF00254.28 EKX53065.1 - 6.4e-12 45.6 0.0 9e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase MORN PF02493.20 EKX53066.1 - 2.5e-24 83.6 33.3 5.4e-07 29.1 1.5 4.1 4 0 0 4 4 4 4 MORN repeat DUF2158 PF09926.9 EKX53066.1 - 0.069 12.9 0.3 2.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2158) Aldedh PF00171.22 EKX53067.1 - 1.5e-178 594.1 0.0 1.7e-178 593.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EKX53067.1 - 0.018 14.5 0.0 0.058 12.8 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) FAST_1 PF06743.15 EKX53068.1 - 0.015 15.3 8.5 12 5.9 0.0 5.5 5 1 1 6 6 6 0 FAST kinase-like protein, subdomain 1 adh_short PF00106.25 EKX53069.1 - 2.5e-44 151.1 0.0 3.5e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EKX53069.1 - 1.3e-39 136.2 0.0 1.9e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX53069.1 - 4.2e-05 23.5 0.6 0.00095 19.1 0.6 2.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EKX53069.1 - 0.015 14.8 0.0 0.019 14.5 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 EKX53069.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF2428 PF10350.9 EKX53070.1 - 2.9e-11 43.1 3.0 2.9e-11 43.1 3.0 3.7 4 1 0 4 4 4 1 Putative death-receptor fusion protein (DUF2428) Spexin PF15171.6 EKX53070.1 - 0.13 12.5 0.4 0.66 10.2 0.4 2.3 1 0 0 1 1 1 0 Neuropeptide secretory protein family, NPQ, spexin Asp_Glu_race PF01177.22 EKX53070.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase HEAT PF02985.22 EKX53070.1 - 1.6 9.2 11.1 4.3 7.9 0.1 5.6 7 0 0 7 7 7 0 HEAT repeat HEAT_EZ PF13513.6 EKX53070.1 - 4 8.1 14.9 0.2 12.2 1.2 4.7 5 0 0 5 5 5 0 HEAT-like repeat NPH-II PF12011.8 EKX53071.1 - 0.083 12.8 0.0 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 RNA helicase NPH-II Med9 PF07544.13 EKX53072.1 - 0.01 15.9 4.4 0.01 15.9 4.4 3.4 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF4145 PF13643.6 EKX53072.1 - 0.098 12.8 2.9 0.25 11.5 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4145) TPR_MLP1_2 PF07926.12 EKX53072.1 - 0.21 11.7 32.9 0.19 11.8 17.8 3.1 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Prominin PF05478.11 EKX53072.1 - 0.43 8.5 15.9 0.13 10.1 4.6 2.0 1 1 1 2 2 2 0 Prominin Tropomyosin_1 PF12718.7 EKX53072.1 - 0.45 10.7 34.7 0.41 10.8 2.5 3.6 1 1 2 3 3 3 0 Tropomyosin like DUF1068 PF06364.12 EKX53072.1 - 3.7 7.4 11.6 4.3 7.2 4.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1068) KELK PF15796.5 EKX53072.1 - 5.5 7.5 20.4 0.3 11.5 1.6 3.7 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Collagen PF01391.18 EKX53073.1 - 8.4e-20 70.3 64.9 49 3.8 64.9 3.0 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) ubiquitin PF00240.23 EKX53074.1 - 0.17 11.7 0.7 1.2 9.0 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin family RCC1 PF00415.18 EKX53075.1 - 1.1e-31 109.1 13.2 9.2e-13 48.6 0.0 4.1 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX53075.1 - 5.4e-31 105.7 18.4 6.6e-12 44.9 2.3 3.5 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RHS_repeat PF05593.14 EKX53075.1 - 0.0098 16.4 0.7 1.1 9.8 0.0 3.1 2 1 0 2 2 2 1 RHS Repeat EGF_2 PF07974.13 EKX53076.1 - 1.3e-12 47.8 86.8 5.9e-07 29.7 12.3 6.6 6 1 0 6 6 6 5 EGF-like domain EGF PF00008.27 EKX53076.1 - 3.2e-06 27.3 3.3 3.2e-06 27.3 3.3 6.0 6 0 0 6 6 6 2 EGF-like domain EGF_Tenascin PF18720.1 EKX53076.1 - 0.00017 21.6 5.4 0.00017 21.6 5.4 5.6 5 0 0 5 5 5 2 Tenascin EGF domain hEGF PF12661.7 EKX53076.1 - 0.00045 20.7 5.4 0.00045 20.7 5.4 7.0 6 0 0 6 6 6 2 Human growth factor-like EGF LapA_dom PF06305.11 EKX53076.1 - 0.061 13.1 0.9 0.091 12.6 0.9 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF4381 PF14316.6 EKX53076.1 - 0.082 13.2 3.0 0.12 12.6 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) HemY_N PF07219.13 EKX53076.1 - 0.29 11.4 4.6 0.42 10.8 4.6 1.1 1 0 0 1 1 1 0 HemY protein N-terminus WD40 PF00400.32 EKX53077.1 - 1.2e-15 57.6 6.6 0.00027 21.7 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 EKX53077.1 - 0.059 12.0 0.2 0.67 8.5 0.1 2.2 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Acetyltransf_1 PF00583.25 EKX53078.1 - 7.2e-05 23.0 0.0 0.00011 22.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EKX53078.1 - 0.00015 21.9 0.0 0.00025 21.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EKX53078.1 - 0.053 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Cupin_8 PF13621.6 EKX53079.1 - 1.2e-40 139.9 0.0 1.9e-40 139.2 0.0 1.3 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EKX53079.1 - 2.3e-09 37.2 0.0 5e-09 36.1 0.0 1.4 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 EKX53079.1 - 0.00043 20.7 0.1 0.00087 19.7 0.1 1.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EKX53079.1 - 0.0013 18.4 0.0 0.01 15.5 0.0 2.4 1 1 1 2 2 2 1 Cupin domain Phosphonate-bd PF12974.7 EKX53080.1 - 3.3e-28 98.9 0.0 4.2e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 EKX53080.1 - 1.5e-06 28.3 0.0 2.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_3 PF16868.5 EKX53080.1 - 0.0085 15.5 0.7 5.3 6.4 0.0 3.0 2 1 0 3 3 3 1 NMT1-like family SBP_bac_3 PF00497.20 EKX53080.1 - 0.0091 15.4 0.1 0.076 12.4 0.1 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lipoprotein_9 PF03180.14 EKX53080.1 - 0.089 11.9 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 NLPA lipoprotein FMO-like PF00743.19 EKX53081.1 - 1.1e-51 175.9 0.0 3.5e-32 111.5 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EKX53081.1 - 3e-18 66.1 0.0 9.6e-15 54.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EKX53081.1 - 8.9e-17 61.3 0.0 5e-15 55.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EKX53081.1 - 2.3e-10 40.2 0.1 3.3e-08 33.0 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EKX53081.1 - 1.3e-08 34.9 0.2 3.2e-08 33.7 0.0 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EKX53081.1 - 2.3e-07 30.8 0.1 0.00074 19.2 0.1 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EKX53081.1 - 9.1e-07 29.0 0.4 0.079 12.9 0.0 4.0 3 1 1 4 4 4 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 EKX53081.1 - 1.4e-05 25.6 0.7 0.24 12.0 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EKX53081.1 - 0.00032 19.9 0.5 0.0019 17.4 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 EKX53081.1 - 0.00041 19.8 0.1 0.72 9.1 0.0 2.8 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase GIDA PF01134.22 EKX53081.1 - 0.00051 19.3 0.2 0.88 8.6 0.0 2.9 3 0 0 3 3 3 2 Glucose inhibited division protein A HI0933_like PF03486.14 EKX53081.1 - 0.0012 17.6 0.7 0.036 12.8 0.1 2.4 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 EKX53081.1 - 0.0013 18.1 0.2 0.0085 15.4 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EKX53081.1 - 0.0014 17.7 0.1 0.27 10.2 0.0 2.5 2 0 0 2 2 2 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 EKX53081.1 - 0.003 17.0 0.1 0.021 14.2 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EKX53081.1 - 0.0033 16.7 0.2 0.029 13.7 0.0 2.4 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain SIS_2 PF13580.6 EKX53081.1 - 0.027 14.5 0.0 0.091 12.8 0.0 1.8 2 0 0 2 2 2 0 SIS domain 3HCDH_N PF02737.18 EKX53081.1 - 0.06 13.2 0.3 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EKX53081.1 - 0.14 12.2 0.3 3.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 EKX53081.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF4147 PF13660.6 EKX53081.1 - 0.15 11.6 0.0 2.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) Peptidase_M17_N PF02789.17 EKX53081.1 - 0.15 11.9 0.6 3.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain Thi4 PF01946.17 EKX53081.1 - 0.21 10.8 1.9 0.35 10.1 0.1 2.2 3 0 0 3 3 3 0 Thi4 family Ion_trans_2 PF07885.16 EKX53082.1 - 0.091 12.7 3.2 0.1 12.6 1.4 2.0 2 0 0 2 2 2 0 Ion channel Cmc1 PF08583.10 EKX53083.1 - 3.5e-06 26.9 1.4 4.6e-06 26.6 1.4 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CEP44 PF15007.6 EKX53084.1 - 3.4e-41 140.4 0.4 8.6e-41 139.1 0.0 1.8 2 0 0 2 2 2 1 Centrosomal spindle body, CEP44 HalX PF08663.10 EKX53084.1 - 0.08 13.3 2.7 0.25 11.7 2.7 1.9 1 0 0 1 1 1 0 HalX domain Methyltransf_28 PF02636.17 EKX53087.1 - 4.3e-63 213.4 0.0 8.3e-63 212.4 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase EF-hand_7 PF13499.6 EKX53087.1 - 3e-11 43.6 0.3 0.0004 20.8 0.1 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX53087.1 - 4.9e-09 35.1 0.3 8e-05 21.9 0.3 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX53087.1 - 1.2e-06 28.0 0.1 0.00044 19.9 0.3 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_9 PF14658.6 EKX53087.1 - 1.5e-06 28.5 0.0 8.3e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 EKX53087.1 - 2e-06 27.6 0.5 0.036 13.9 0.0 3.5 2 1 1 3 3 3 2 EF-hand domain pair EcsC PF12787.7 EKX53087.1 - 0.0044 16.7 0.6 0.0092 15.7 0.1 1.7 2 0 0 2 2 2 1 EcsC protein family EF-hand_5 PF13202.6 EKX53087.1 - 0.008 15.6 0.3 0.019 14.5 0.3 1.6 1 0 0 1 1 1 1 EF hand Flagellin_N PF00669.20 EKX53087.1 - 0.0092 16.1 1.0 0.031 14.4 1.0 1.9 1 0 0 1 1 1 1 Bacterial flagellin N-terminal helical region NRDE-2 PF08424.10 EKX53087.1 - 0.039 13.1 0.2 0.076 12.1 0.2 1.4 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference DUF16 PF01519.16 EKX53087.1 - 0.46 11.0 3.7 0.41 11.2 0.7 2.4 3 0 0 3 3 3 0 Protein of unknown function DUF16 Cofilin_ADF PF00241.20 EKX53088.1 - 3e-20 72.2 0.9 4.3e-18 65.3 0.1 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein BLM10_mid PF16507.5 EKX53089.1 - 1.7e-34 119.4 0.1 9.1e-18 64.2 0.0 2.7 1 1 1 2 2 2 2 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EKX53089.1 - 7.9e-20 70.6 0.3 2.6e-18 65.7 0.0 3.5 3 1 1 4 4 4 1 Domain of unknown function (DUF3437) HEAT_2 PF13646.6 EKX53089.1 - 2e-05 24.9 3.3 0.019 15.3 0.0 4.9 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 EKX53089.1 - 0.00013 21.9 1.2 2.7 8.5 0.0 5.8 6 0 0 6 6 6 1 HEAT repeat IFRD PF05004.13 EKX53089.1 - 0.0097 15.0 1.1 0.028 13.5 0.1 2.2 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) MBOAT_2 PF13813.6 EKX53089.1 - 0.01 16.1 2.2 0.02 15.1 0.5 2.4 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family Cnd1 PF12717.7 EKX53089.1 - 0.048 13.7 1.0 3.8 7.5 0.0 3.7 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 CBM_2 PF00553.19 EKX53090.1 - 3.5e-10 40.1 0.4 5.9e-10 39.4 0.4 1.4 1 0 0 1 1 1 1 Cellulose binding domain DUF3605 PF12239.8 EKX53090.1 - 0.0028 18.0 1.4 0.013 15.9 1.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) XRCC4 PF06632.12 EKX53090.1 - 4.9 5.9 8.5 7.3 5.3 8.5 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 adh_short_C2 PF13561.6 EKX53091.1 - 8e-45 153.2 0.0 2.4e-42 145.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EKX53091.1 - 6.6e-05 22.5 0.0 0.0025 17.3 0.0 2.3 2 1 0 2 2 2 1 short chain dehydrogenase Enoyl_reductase PF12241.8 EKX53091.1 - 0.12 11.7 0.0 12 5.1 0.0 2.1 2 0 0 2 2 2 0 Trans-2-enoyl-CoA reductase catalytic region EPL1 PF10513.9 EKX53092.1 - 0.1 13.0 2.9 0.19 12.1 2.9 1.5 1 1 0 1 1 1 0 Enhancer of polycomb-like Guanylate_cyc PF00211.20 EKX53093.1 - 6.5e-17 61.7 0.0 7e-17 61.6 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 EKX53094.1 - 6.4e-32 110.6 0.4 7.7e-32 110.4 0.4 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Nrap_D5 PF17406.2 EKX53094.1 - 0.021 14.6 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Nrap protein PAP/OAS1-like domain 5 FRG1 PF06229.12 EKX53094.1 - 0.12 12.1 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 FRG1-like domain Kelch_1 PF01344.25 EKX53095.1 - 4.4e-54 179.8 14.5 2.5e-12 46.2 1.1 6.4 6 1 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 EKX53095.1 - 5.1e-35 118.6 11.3 2.3e-08 34.0 0.1 6.5 1 1 5 6 6 6 6 Kelch motif Kelch_2 PF07646.15 EKX53095.1 - 1.6e-24 84.9 3.7 4e-05 23.4 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EKX53095.1 - 8.6e-23 80.1 12.1 4e-08 33.4 0.1 7.0 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.6 EKX53095.1 - 3.1e-20 71.9 4.9 1.5e-06 28.1 0.0 5.3 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EKX53095.1 - 4e-11 42.6 6.9 0.011 15.7 1.0 6.0 6 0 0 6 6 6 3 Kelch motif UCH PF00443.29 EKX53096.1 - 0.0022 17.6 0.0 0.0022 17.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PBP_like_2 PF12849.7 EKX53097.1 - 0.065 12.9 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 PBP superfamily domain MORN PF02493.20 EKX53099.1 - 8.2e-16 56.9 5.1 1.4e-05 24.6 0.1 4.0 4 0 0 4 4 4 4 MORN repeat NumbF PF06311.12 EKX53100.1 - 0.05 14.1 0.2 0.14 12.7 0.2 1.8 1 1 0 1 1 1 0 NUMB domain DUF572 PF04502.13 EKX53100.1 - 0.19 11.4 7.6 0.2 11.2 7.3 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF572) Glyco_hydro_2 PF00703.21 EKX53101.1 - 1.1e-09 39.0 0.0 1.8e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 MFS_1 PF07690.16 EKX53102.1 - 2.4e-27 95.8 7.6 3.2e-27 95.4 7.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EKX53102.1 - 1.5e-13 50.5 0.3 1.8e-13 50.2 0.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 EKX53102.1 - 2e-07 30.6 3.4 1.5e-05 24.5 1.1 2.2 1 1 1 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 EKX53102.1 - 0.0012 17.8 3.8 0.0099 14.8 3.8 2.2 1 1 0 1 1 1 1 MFS_1 like family MFS_2 PF13347.6 EKX53102.1 - 0.0023 16.6 0.5 0.0051 15.4 0.5 1.5 1 0 0 1 1 1 1 MFS/sugar transport protein Ank PF00023.30 EKX53103.1 - 7.1e-25 86.3 3.6 8.5e-07 29.1 0.0 4.4 4 1 1 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EKX53103.1 - 7.3e-25 84.3 3.5 1e-05 25.5 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_2 PF12796.7 EKX53103.1 - 4.3e-24 84.9 2.2 8.7e-15 55.1 0.4 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX53103.1 - 1.3e-22 79.8 4.7 3.6e-09 37.0 0.1 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX53103.1 - 3.5e-19 68.6 14.9 8.2e-08 32.4 1.1 4.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) RhoGEF PF00621.20 EKX53105.1 - 0.002 18.4 0.9 1.7 8.8 0.0 2.9 3 0 0 3 3 3 2 RhoGEF domain Snapin_Pallidin PF14712.6 EKX53105.1 - 0.023 15.1 2.7 0.11 13.0 0.4 2.4 2 0 0 2 2 2 0 Snapin/Pallidin PH PF00169.29 EKX53105.1 - 0.096 13.2 0.0 0.26 11.8 0.0 1.7 1 1 0 1 1 1 0 PH domain PhoR PF11808.8 EKX53106.1 - 0.0012 19.2 0.0 0.0019 18.5 0.0 1.2 1 0 0 1 1 1 1 Phosphate regulon sensor protein PhoR ATP-synt_F6 PF05511.11 EKX53106.1 - 0.078 13.4 0.3 0.21 12.0 0.3 1.7 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 DHR-2 PF06920.13 EKX53106.1 - 0.096 11.3 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Dock homology region 2 Pkinase PF00069.25 EKX53107.1 - 8.5e-47 159.7 0.0 1e-46 159.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX53107.1 - 1.1e-28 100.3 0.0 1.2e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX53107.1 - 7.2e-06 25.5 0.1 1.2e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX53107.1 - 0.00032 20.7 0.1 0.0039 17.2 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.20 EKX53107.1 - 0.0063 15.9 0.0 0.0089 15.4 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Kinase-like PF14531.6 EKX53107.1 - 0.0064 15.8 0.0 0.26 10.5 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EKX53107.1 - 0.0096 14.9 0.1 0.39 9.6 0.1 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EKX53107.1 - 0.011 14.5 0.0 0.085 11.6 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase Choline_kinase PF01633.20 EKX53107.1 - 0.09 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase AAA_12 PF13087.6 EKX53108.1 - 1.1e-06 28.5 0.1 0.0001 22.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EKX53108.1 - 0.071 12.3 0.0 0.098 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FHA PF00498.26 EKX53109.1 - 3.2e-13 49.8 0.0 6.6e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EKX53109.1 - 4.5e-08 33.3 0.0 2.1e-07 31.2 0.0 2.0 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain PH PF00169.29 EKX53109.1 - 3.9e-06 27.3 0.1 8.4e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 PH domain Guanylate_cyc PF00211.20 EKX53110.1 - 8.5e-15 54.8 0.0 1.1e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Suv3_C_1 PF18147.1 EKX53111.1 - 2.2e-13 49.8 0.6 5.6e-13 48.5 0.2 1.9 2 0 0 2 2 2 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 EKX53111.1 - 2.7e-09 37.4 0.0 8.7e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SUV3_C PF12513.8 EKX53111.1 - 8.4e-08 32.0 0.0 2.8e-07 30.4 0.0 1.9 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Pkinase PF00069.25 EKX53112.1 - 4.4e-26 91.8 0.0 5.5e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX53112.1 - 1.5e-16 60.5 0.0 2.2e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX53112.1 - 2.7e-06 26.9 0.0 5.5e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EKX53112.1 - 0.0012 18.9 0.2 1 9.2 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 EKX53112.1 - 0.0076 15.9 0.1 0.22 11.1 0.0 2.1 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 DUF2712 PF10916.8 EKX53112.1 - 0.2 12.3 0.0 0.35 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2712) AMP-binding PF00501.28 EKX53113.1 - 4.9e-56 190.1 0.1 5.8e-56 189.9 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme ubiquitin PF00240.23 EKX53115.1 - 0.0024 17.6 0.1 0.0099 15.6 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family HEAT_EZ PF13513.6 EKX53117.1 - 0.0063 17.0 0.3 18 5.9 0.0 4.3 5 0 0 5 5 5 1 HEAT-like repeat RasGEF_N_2 PF14663.6 EKX53117.1 - 0.14 12.5 0.6 11 6.5 0.1 3.0 2 1 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain V-ATPase_H_N PF03224.14 EKX53117.1 - 0.21 10.9 4.6 0.65 9.2 1.9 2.9 1 1 2 3 3 3 0 V-ATPase subunit H RICTOR_V PF14668.6 EKX53117.1 - 0.23 11.7 1.6 9.6 6.5 0.0 3.4 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 Arm PF00514.23 EKX53117.1 - 0.86 9.7 8.7 8.6 6.6 0.1 4.9 5 1 0 5 5 5 0 Armadillo/beta-catenin-like repeat Collagen PF01391.18 EKX53118.1 - 3.7e-09 36.2 28.4 7.3e-09 35.3 28.4 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) TBD PF12845.7 EKX53118.1 - 0.052 13.4 0.2 0.68 9.9 0.1 2.4 2 0 0 2 2 2 0 TBD domain UPF0184 PF03670.13 EKX53118.1 - 0.053 13.9 0.5 1.4 9.4 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Neur_chan_memb PF02932.16 EKX53118.1 - 4.3 7.3 6.2 2.8 7.9 4.1 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region MORN PF02493.20 EKX53119.1 - 9.4e-23 78.7 27.1 2e-06 27.3 3.9 4.8 5 0 0 5 5 5 4 MORN repeat EF-hand_1 PF00036.32 EKX53121.1 - 2.6e-16 57.9 0.1 3.1e-07 29.5 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX53121.1 - 4.2e-15 56.0 0.2 5.1e-15 55.7 0.2 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EKX53121.1 - 2.2e-13 49.8 0.7 3.2e-13 49.3 0.2 1.5 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX53121.1 - 9.6e-13 47.0 0.5 8e-06 25.4 0.1 2.2 1 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EKX53121.1 - 1.3e-09 37.1 0.3 0.00038 19.8 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 EKX53121.1 - 0.00049 20.4 0.0 0.00057 20.1 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain SPARC_Ca_bdg PF10591.9 EKX53121.1 - 0.0023 18.2 0.1 0.0026 18.1 0.1 1.1 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region DUF1456 PF07308.13 EKX53121.1 - 0.013 15.9 0.1 0.018 15.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) EF-hand_4 PF12763.7 EKX53121.1 - 0.077 13.0 0.2 0.22 11.5 0.3 1.6 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Peptidase_M24 PF00557.24 EKX53121.1 - 0.099 12.3 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 Metallopeptidase family M24 EF-hand_10 PF14788.6 EKX53121.1 - 0.12 12.3 1.5 0.81 9.6 0.7 2.1 1 1 1 2 2 2 0 EF hand CP12 PF02672.15 EKX53121.1 - 0.36 11.6 3.2 4.8 8.0 3.2 2.0 1 1 0 1 1 1 0 CP12 domain PDZ_6 PF17820.1 EKX53122.1 - 6.7e-06 25.9 0.0 1.5e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX53122.1 - 0.0022 18.3 0.0 0.0039 17.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain EI24 PF07264.11 EKX53122.1 - 0.036 14.3 0.0 0.043 14.0 0.0 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF4131 PF13567.6 EKX53122.1 - 0.037 13.7 0.2 0.31 10.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) SNF PF00209.18 EKX53122.1 - 0.04 12.6 0.0 0.047 12.4 0.0 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family MAP17 PF15807.5 EKX53122.1 - 0.058 13.6 0.0 0.095 12.9 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 LRR19-TM PF15176.6 EKX53122.1 - 0.063 13.3 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain FAM163 PF15069.6 EKX53122.1 - 0.075 13.5 0.1 0.12 12.8 0.1 1.3 1 0 0 1 1 1 0 FAM163 family DUF4227 PF14004.6 EKX53122.1 - 0.1 12.6 1.1 0.46 10.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4227) Abhydrolase_9_N PF15420.6 EKX53122.1 - 0.12 12.4 0.1 0.17 11.9 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus Insulin_TMD PF17870.1 EKX53122.1 - 0.16 12.0 0.7 2.2 8.4 0.2 2.2 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Ank_4 PF13637.6 EKX53123.1 - 2.2e-18 66.4 0.2 7.7e-09 35.9 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX53123.1 - 1.3e-13 51.3 0.0 1.5e-13 51.2 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX53123.1 - 7.5e-13 48.4 0.0 1e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX53123.1 - 2.5e-11 42.8 0.0 0.00016 21.9 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 EKX53123.1 - 4.7e-09 36.3 0.1 0.00012 22.3 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 EKX53124.1 - 9.8e-21 74.1 4.9 8.4e-12 45.5 1.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX53124.1 - 2.8e-20 72.4 1.2 5e-09 36.5 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX53124.1 - 2.1e-18 66.1 0.5 6.9e-11 42.2 0.2 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX53124.1 - 3.5e-14 51.5 0.1 8.4e-05 22.7 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EKX53124.1 - 4.4e-14 52.2 0.9 5.2e-05 23.5 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EKX53125.1 - 2.4e-14 53.5 0.0 1.3e-10 41.6 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX53125.1 - 3.7e-12 46.7 0.0 4e-12 46.6 0.0 1.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX53125.1 - 4.1e-12 46.1 0.1 5.7e-12 45.6 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX53125.1 - 8.2e-10 38.7 0.1 1e-07 32.1 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EKX53125.1 - 1.1e-09 37.7 0.1 3.2e-07 30.1 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Peptidase_C97 PF05903.14 EKX53126.1 - 9.5e-06 25.5 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain HTH_25 PF13413.6 EKX53126.1 - 0.033 14.1 0.1 0.068 13.0 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain 2OG-FeII_Oxy_3 PF13640.6 EKX53127.1 - 1e-10 42.4 0.0 1.3e-10 42.0 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4131 PF13567.6 EKX53128.1 - 0.07 12.8 0.0 0.14 11.8 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) FliG_N PF14842.6 EKX53128.1 - 0.11 13.0 2.9 0.83 10.2 0.2 3.1 2 1 0 3 3 3 0 FliG N-terminal domain Ribosomal_L12 PF00542.19 EKX53128.1 - 0.14 12.6 4.3 1.5 9.2 0.1 3.0 3 0 0 3 3 3 0 Ribosomal protein L7/L12 C-terminal domain ABA_WDS PF02496.16 EKX53128.1 - 0.18 12.3 0.9 1.3 9.6 0.1 2.3 2 0 0 2 2 2 0 ABA/WDS induced protein DAHP_snth_FXD PF18152.1 EKX53128.1 - 0.19 11.6 0.4 1.3 9.0 0.1 2.3 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain Tox-WTIP PF15654.6 EKX53128.1 - 1.5 9.3 3.3 4.3 7.8 0.3 2.4 2 0 0 2 2 2 0 Toxin with a conserved tryptophan and TIP tripeptide motif zf-RING_2 PF13639.6 EKX53129.1 - 4e-05 23.9 13.9 7.6e-05 23.0 13.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EKX53129.1 - 0.00026 20.7 10.9 0.00057 19.6 10.9 1.6 1 0 0 1 1 1 1 RING-like zinc finger PHD PF00628.29 EKX53129.1 - 0.0048 16.7 11.6 0.009 15.9 11.6 1.5 1 0 0 1 1 1 1 PHD-finger zf-RING_UBOX PF13445.6 EKX53129.1 - 0.016 15.2 6.8 0.016 15.2 6.8 1.9 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.6 EKX53129.1 - 0.16 12.0 13.5 0.13 12.3 11.5 2.0 2 1 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EKX53129.1 - 0.2 11.5 13.9 0.62 10.0 13.9 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX53129.1 - 0.65 9.9 12.3 1.2 9.0 12.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_1 PF00515.28 EKX53130.1 - 4.4 7.3 6.3 37 4.4 0.6 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat Acetyltransf_1 PF00583.25 EKX53131.1 - 3.3e-16 59.6 0.0 4.7e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EKX53131.1 - 2.9e-11 43.4 0.1 3.5e-11 43.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EKX53131.1 - 1.3e-08 35.1 0.0 1.9e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EKX53131.1 - 1.5e-08 34.5 0.0 2.1e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EKX53131.1 - 0.0042 17.2 0.3 0.0062 16.7 0.3 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EKX53131.1 - 0.083 13.6 0.0 0.12 13.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EKX53131.1 - 0.098 12.6 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase AAA PF00004.29 EKX53132.1 - 6.1e-40 136.7 0.0 1.2e-30 106.6 0.0 3.4 2 1 1 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EKX53132.1 - 1.4e-19 69.6 0.2 1.2e-11 44.2 0.1 2.8 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EKX53132.1 - 1.6e-05 25.3 0.0 0.016 15.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EKX53132.1 - 5.4e-05 23.5 0.1 0.059 13.7 0.1 3.2 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 EKX53132.1 - 0.003 17.6 0.0 0.18 11.8 0.0 2.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 EKX53132.1 - 0.0033 16.6 0.0 0.0064 15.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 EKX53132.1 - 0.0098 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_29 PF13555.6 EKX53132.1 - 0.014 15.1 0.0 0.047 13.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_33 PF13671.6 EKX53132.1 - 0.052 13.7 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EKX53132.1 - 0.064 12.8 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 EKX53132.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 EKX53132.1 - 0.17 12.0 0.0 3.4 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) DSPc PF00782.20 EKX53133.1 - 3.3e-05 23.7 0.0 0.00022 21.0 0.0 1.9 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX53133.1 - 0.00014 21.6 0.0 0.00016 21.3 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EKX53133.1 - 0.0023 17.9 0.0 0.0026 17.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EKX53133.1 - 0.0031 17.7 0.0 0.0037 17.4 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPn PF14671.6 EKX53133.1 - 0.035 14.6 0.0 0.05 14.0 0.0 1.3 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half PuR_N PF09182.10 EKX53133.1 - 0.15 12.0 0.0 0.41 10.6 0.0 1.7 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal Put_Phosphatase PF06888.12 EKX53136.1 - 5.9e-47 160.0 0.0 6.6e-47 159.9 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 EKX53136.1 - 3.6e-08 34.0 0.0 8.1e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Stathmin PF00836.19 EKX53137.1 - 2e-09 37.5 60.7 0.0057 16.6 19.1 4.6 1 1 3 4 4 4 4 Stathmin family UvrB PF12344.8 EKX53137.1 - 3.4 7.6 6.6 23 4.9 3.5 3.0 2 0 0 2 2 2 0 Ultra-violet resistance protein B SR-25 PF10500.9 EKX53138.1 - 0.0041 16.8 15.3 0.0055 16.3 15.3 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein FAM110_C PF14160.6 EKX53138.1 - 0.15 13.2 5.2 0.21 12.7 4.3 1.6 2 0 0 2 2 2 0 Centrosome-associated C terminus MORN PF02493.20 EKX53140.1 - 8.7e-25 85.1 51.7 8.2e-07 28.6 2.6 8.5 8 0 0 8 8 8 7 MORN repeat zf-RVT PF13966.6 EKX53141.1 - 0.065 13.9 1.4 0.25 12.1 0.3 2.5 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase VF530 PF09905.9 EKX53141.1 - 0.08 13.1 0.1 0.24 11.6 0.1 1.8 1 0 0 1 1 1 0 DNA-binding protein VF530 SRPRB PF09439.10 EKX53144.1 - 5.9e-34 117.1 0.0 8.1e-34 116.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 EKX53144.1 - 3.4e-08 33.1 0.0 4.9e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EKX53144.1 - 1.4e-07 31.3 0.0 7.4e-06 25.6 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EKX53144.1 - 8.1e-07 29.1 0.0 1.9e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EKX53144.1 - 1.1e-06 28.9 0.0 2.5e-06 27.7 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 EKX53144.1 - 0.0014 18.2 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.22 EKX53144.1 - 0.004 16.8 0.0 0.0072 15.9 0.0 1.4 1 1 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EKX53144.1 - 0.008 15.6 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF456 PF04306.13 EKX53144.1 - 0.037 14.3 1.6 0.063 13.6 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) PduV-EutP PF10662.9 EKX53144.1 - 0.072 12.8 0.0 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Yip1 PF04893.17 EKX53144.1 - 0.11 12.2 0.4 0.17 11.6 0.4 1.2 1 0 0 1 1 1 0 Yip1 domain G-alpha PF00503.20 EKX53144.1 - 0.25 10.4 0.0 1.1 8.3 0.0 2.0 1 1 1 2 2 2 0 G-protein alpha subunit Adaptin_N PF01602.20 EKX53145.1 - 2.2e-89 300.4 7.6 2.8e-89 300.0 7.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EKX53145.1 - 3.1e-07 30.6 0.0 3.1e-07 30.6 0.0 2.9 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 EKX53145.1 - 0.00084 18.6 1.2 0.29 10.3 0.0 2.7 2 1 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 EKX53145.1 - 0.0013 19.1 0.1 0.089 13.2 0.0 3.4 3 0 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 EKX53145.1 - 0.0015 18.9 0.0 0.14 12.7 0.0 3.1 2 0 0 2 2 2 1 HEAT-like repeat RTP1_C1 PF10363.9 EKX53145.1 - 0.0073 16.5 0.3 3.8 7.7 0.0 4.3 3 2 2 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 EKX53145.1 - 0.014 16.0 0.5 4.6 7.9 0.2 3.2 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EKX53145.1 - 0.015 15.5 0.3 0.38 11.1 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat FA_hydroxylase PF04116.13 EKX53146.1 - 3.5e-23 82.4 16.0 5e-23 81.9 16.0 1.2 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily DUF588 PF04535.12 EKX53146.1 - 0.014 15.2 0.9 4.6 7.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF588) ACT_4 PF13291.6 EKX53147.1 - 0.048 14.2 0.4 0.69 10.5 0.1 2.1 2 0 0 2 2 2 0 ACT domain Comm PF15957.5 EKX53148.1 - 0.13 12.6 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Commissureless LMBR1 PF04791.16 EKX53151.1 - 1.3e-31 110.1 33.3 2.5e-25 89.4 8.3 2.1 1 1 1 2 2 2 2 LMBR1-like membrane protein ATP1G1_PLM_MAT8 PF02038.16 EKX53151.1 - 0.024 14.1 0.3 0.071 12.6 0.3 1.8 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family TMEM52 PF14979.6 EKX53151.1 - 0.61 10.0 0.0 0.61 10.0 0.0 3.9 4 0 0 4 4 4 0 Transmembrane 52 PP2C PF00481.21 EKX53152.1 - 6.2e-73 245.6 0.4 1.1e-57 195.7 0.3 2.0 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EKX53152.1 - 0.0033 17.1 0.0 0.0065 16.1 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C LRR_9 PF14580.6 EKX53153.1 - 6e-16 58.4 1.8 2.7e-15 56.3 1.4 2.3 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EKX53153.1 - 2.1e-12 47.1 19.8 5.1e-08 33.1 4.4 4.0 2 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX53153.1 - 7.3e-09 35.3 18.2 9e-06 25.4 9.7 3.0 2 1 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 EKX53153.1 - 2.6 8.3 9.5 0.96 9.7 0.7 4.1 3 1 1 4 4 4 0 Leucine Rich repeat DUF1977 PF09320.11 EKX53153.1 - 8.6 6.7 10.6 0.16 12.3 2.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1977) Ephrin_rec_like PF07699.13 EKX53154.1 - 2.7e-30 103.9 64.9 1.5e-05 24.7 2.3 8.6 3 2 6 9 9 9 9 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX53154.1 - 8.1e-11 42.1 48.0 0.075 13.5 0.4 9.7 4 2 8 12 12 12 9 TNFR/NGFR cysteine-rich region VSP PF03302.13 EKX53154.1 - 0.0013 17.7 61.4 0.0074 15.2 8.5 4.0 1 1 2 4 4 4 3 Giardia variant-specific surface protein DUF2318 PF10080.9 EKX53154.1 - 0.12 12.5 43.0 0.38 10.9 0.7 6.6 1 1 5 6 6 6 0 Predicted membrane protein (DUF2318) Laminin_EGF PF00053.24 EKX53154.1 - 3.6 7.8 48.4 51 4.1 2.6 9.2 3 2 2 5 5 5 0 Laminin EGF domain Ephrin_rec_like PF07699.13 EKX53155.1 - 1.2e-62 207.5 128.3 7.2e-10 38.5 8.8 12.2 4 2 9 13 13 13 13 Putative ephrin-receptor like NCD3G PF07562.14 EKX53155.1 - 1.2e-11 44.4 100.4 0.039 13.9 5.9 11.5 5 2 8 13 13 13 12 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX53155.1 - 0.00059 20.2 101.0 0.082 13.3 0.6 14.6 4 3 7 14 14 14 7 TNFR/NGFR cysteine-rich region Asparaginase_2 PF01112.18 EKX53155.1 - 0.023 13.7 0.3 0.042 12.9 0.3 1.3 1 0 0 1 1 1 0 Asparaginase VSP PF03302.13 EKX53155.1 - 0.59 8.9 98.0 0.086 11.7 21.6 5.3 1 1 3 5 5 5 0 Giardia variant-specific surface protein COG5 PF10392.9 EKX53156.1 - 0.013 15.7 0.1 0.018 15.2 0.1 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF4094 PF13334.6 EKX53156.1 - 0.16 12.4 6.2 0.73 10.3 6.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) Tim17 PF02466.19 EKX53157.1 - 4.2e-11 43.2 7.2 5.9e-11 42.7 7.2 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Romo1 PF10247.9 EKX53157.1 - 2.9e-05 24.4 3.9 2.9e-05 24.4 3.9 2.2 2 0 0 2 2 2 1 Reactive mitochondrial oxygen species modulator 1 XPC-binding PF09280.11 EKX53158.1 - 5.2e-19 67.7 2.1 1.5e-18 66.2 2.1 1.9 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 EKX53158.1 - 1e-17 63.7 2.0 4.8e-11 42.3 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 EKX53158.1 - 2.8e-06 27.0 1.1 1.7e-05 24.5 0.2 2.6 2 1 0 2 2 2 1 Ubiquitin family Rad60-SLD_2 PF13881.6 EKX53158.1 - 1.9e-05 24.8 0.0 4.1e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 EKX53158.1 - 0.0094 16.0 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 EKX53158.1 - 0.063 13.1 0.1 0.18 11.6 0.1 1.8 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like SBP_bac_5 PF00496.22 EKX53158.1 - 0.12 11.3 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle DUF2695 PF10905.8 EKX53158.1 - 0.19 11.9 0.3 0.9 9.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2695) ThiF PF00899.21 EKX53159.1 - 7.1e-84 281.0 0.0 3.3e-58 196.9 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EKX53159.1 - 2.3e-72 244.0 0.6 3.7e-72 243.3 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_4HB PF16191.5 EKX53159.1 - 6.4e-18 64.7 3.1 7.7e-18 64.5 0.4 2.4 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_FCCH PF16190.5 EKX53159.1 - 1.8e-13 50.5 0.2 4.1e-13 49.3 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 EKX53159.1 - 0.00015 22.4 0.2 0.00042 21.0 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin fold domain Pkinase PF00069.25 EKX53160.1 - 4.7e-54 183.5 0.0 6.1e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX53160.1 - 3.8e-36 124.7 0.0 4.8e-36 124.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX53160.1 - 6.8e-06 25.1 0.0 1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX53160.1 - 2.3e-05 24.5 0.1 0.028 14.3 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 EKX53160.1 - 0.0014 18.0 0.2 0.0021 17.5 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EKX53160.1 - 0.0044 16.6 0.0 0.0065 16.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EKX53160.1 - 0.011 15.0 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like YrbL-PhoP_reg PF10707.9 EKX53160.1 - 0.06 12.9 0.0 0.086 12.4 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL MATH PF00917.26 EKX53162.1 - 2e-14 53.7 0.0 5.5e-14 52.3 0.0 1.8 1 0 0 1 1 1 1 MATH domain Ribosomal_L38e PF01781.18 EKX53163.1 - 6.1e-35 119.1 2.0 6.7e-35 119.0 2.0 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family PB1 PF00564.24 EKX53164.1 - 1.4e-05 24.9 0.3 5.4e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 PB1 domain DUF1647 PF07801.11 EKX53164.1 - 0.11 12.2 0.6 0.44 10.3 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1647) YvbH_ext PF11724.8 EKX53164.1 - 0.13 12.6 1.5 0.49 10.8 0.9 2.2 2 0 0 2 2 2 0 YvbH-like oligomerisation region Piezo_RRas_bdg PF12166.8 EKX53164.1 - 1.6 7.9 5.0 2 7.6 5.0 1.0 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain GET2 PF08690.10 EKX53164.1 - 2.9 7.5 15.6 3.6 7.2 15.6 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 PA26 PF04636.13 EKX53164.1 - 3.2 6.6 12.8 4.3 6.2 12.8 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) V_ATPase_I PF01496.19 EKX53164.1 - 4.6 5.0 16.3 5.9 4.7 16.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lin-8 PF03353.15 EKX53164.1 - 5.5 6.5 18.0 7.3 6.1 18.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PDZ_6 PF17820.1 EKX53165.1 - 3.5e-05 23.6 0.0 0.00015 21.5 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX53165.1 - 0.0051 17.1 0.1 0.014 15.8 0.1 1.7 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX53165.1 - 0.081 12.9 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 Tricorn protease PDZ domain LRR_6 PF13516.6 EKX53167.1 - 0.085 13.0 5.6 36 4.8 0.2 6.7 7 0 0 7 7 7 0 Leucine Rich repeat F420_oxidored PF03807.17 EKX53168.1 - 0.042 14.4 0.2 0.17 12.5 0.1 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 EKX53168.1 - 0.16 12.3 0.4 0.86 9.9 0.1 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain LysM PF01476.20 EKX53169.1 - 3.6e-06 26.9 0.0 7.9e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 LysM domain WD40 PF00400.32 EKX53171.1 - 9.5e-11 42.1 7.0 0.0014 19.4 0.2 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX53171.1 - 1.6e-05 25.1 0.7 1.2 9.5 0.0 4.4 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 EKX53171.1 - 0.042 13.6 0.3 0.62 9.7 0.0 2.4 2 0 0 2 2 2 0 TUP1-like enhancer of split bZIP_1 PF00170.21 EKX53171.1 - 0.071 13.2 0.4 0.17 12.0 0.4 1.6 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 EKX53171.1 - 0.096 12.8 0.5 0.096 12.8 0.5 1.8 2 0 0 2 2 2 0 Basic region leucine zipper M PF02370.16 EKX53171.1 - 0.29 11.8 2.3 1.5 9.6 2.3 2.3 1 0 0 1 1 1 0 M protein repeat Med12 PF09497.10 EKX53172.1 - 1.2e-09 38.3 0.2 4.3e-09 36.5 0.1 2.1 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 EKX53172.1 - 3.3e-07 29.5 0.0 3.3e-07 29.5 0.0 1.9 2 1 0 2 2 2 1 Eukaryotic Mediator 12 subunit domain DUF677 PF05055.12 EKX53172.1 - 0.087 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Ank_2 PF12796.7 EKX53173.1 - 1.2e-30 105.9 0.4 3e-13 50.2 0.1 2.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX53173.1 - 1.8e-23 82.5 2.2 4.4e-12 46.3 0.1 2.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX53173.1 - 2.4e-21 75.1 1.6 4.8e-06 26.8 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EKX53173.1 - 1.4e-20 73.0 1.6 8.3e-10 38.7 0.1 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX53173.1 - 1.8e-19 67.8 0.5 1.4e-06 28.1 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat EF-hand_1 PF00036.32 EKX53174.1 - 1.5e-05 24.2 1.9 0.0015 17.9 0.4 2.9 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 EKX53174.1 - 1.9e-05 24.5 0.0 0.0064 16.4 0.0 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 EKX53174.1 - 7.2e-05 23.2 0.0 0.039 14.4 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX53174.1 - 0.0011 18.7 0.2 0.02 14.8 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 EKX53174.1 - 0.0046 16.8 4.1 0.26 11.2 0.6 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX53174.1 - 0.021 14.3 1.3 0.05 13.1 0.2 2.1 2 0 0 2 2 2 0 EF hand Ribosomal_L22 PF00237.19 EKX53174.1 - 0.033 14.4 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e HAP1_N PF04849.13 EKX53175.1 - 0.0005 19.4 23.8 0.00062 19.1 23.8 1.1 1 0 0 1 1 1 1 HAP1 N-terminal conserved region Glyco_hydro_67C PF07477.12 EKX53175.1 - 0.065 12.8 7.0 0.4 10.2 0.9 2.1 1 1 1 2 2 2 0 Glycosyl hydrolase family 67 C-terminus DUF3685 PF12452.8 EKX53175.1 - 0.083 12.6 5.8 0.12 12.1 5.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3685) HIP1_clath_bdg PF16515.5 EKX53175.1 - 0.8 10.4 28.3 0.45 11.1 14.5 2.8 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Tweety PF04906.13 EKX53175.1 - 0.83 8.3 5.0 0.2 10.3 1.4 1.6 1 1 1 2 2 2 0 Tweety Fib_alpha PF08702.10 EKX53175.1 - 0.94 9.7 19.4 0.44 10.7 6.3 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Golgin_A5 PF09787.9 EKX53175.1 - 0.99 8.8 30.6 2.5 7.5 29.7 1.7 1 1 0 1 1 1 0 Golgin subfamily A member 5 YlbE PF14003.6 EKX53175.1 - 1 9.8 10.1 2.7 8.5 3.2 3.3 2 1 1 3 3 3 0 YlbE-like protein Exonuc_VII_L PF02601.15 EKX53175.1 - 1.2 8.7 14.7 1.6 8.3 14.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ORF6C PF10552.9 EKX53175.1 - 1.2 9.3 9.9 0.1 12.7 2.9 2.4 1 1 1 2 2 2 0 ORF6C domain Fzo_mitofusin PF04799.13 EKX53175.1 - 3 7.4 14.7 0.29 10.7 7.1 2.2 2 0 0 2 2 2 0 fzo-like conserved region DUF1664 PF07889.12 EKX53175.1 - 4.9 7.2 11.8 2.2 8.3 2.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 EKX53175.1 - 5.9 6.2 17.0 15 4.8 17.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Ax_dynein_light PF10211.9 EKX53175.1 - 6.4 6.7 30.1 1.4 8.9 10.9 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain Lectin_N PF03954.14 EKX53175.1 - 6.6 6.5 12.4 0.37 10.5 1.7 2.2 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain ERM PF00769.19 EKX53175.1 - 7.6 6.3 35.1 32 4.2 35.1 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family ADIP PF11559.8 EKX53175.1 - 8.3 6.5 25.6 1.6 8.8 14.4 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding PHD PF00628.29 EKX53176.1 - 8.2e-10 38.4 11.6 1.7e-09 37.4 11.6 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EKX53176.1 - 0.0012 19.0 4.1 0.0032 17.7 4.1 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain DUF2203 PF09969.9 EKX53176.1 - 0.012 16.3 0.1 0.051 14.3 0.1 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) PHD_2 PF13831.6 EKX53176.1 - 4.3 7.0 9.9 0.17 11.5 3.5 2.1 2 0 0 2 2 2 0 PHD-finger CTP_synth_N PF06418.14 EKX53177.1 - 2.2e-116 387.8 0.1 2.8e-116 387.5 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EKX53177.1 - 1.1e-51 175.3 0.0 1.7e-51 174.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EKX53177.1 - 7.1e-05 22.7 0.1 0.00032 20.5 0.0 2.1 1 1 1 2 2 2 1 Peptidase C26 CbiA PF01656.23 EKX53177.1 - 0.0016 18.5 0.0 0.0029 17.6 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Ank_4 PF13637.6 EKX53178.1 - 1.1e-16 61.0 0.3 4.2e-09 36.8 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX53178.1 - 1.8e-11 44.4 0.0 2.6e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX53178.1 - 8.4e-09 35.5 1.6 1.9e-05 24.9 0.3 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX53178.1 - 1.4e-08 34.3 0.1 9.1e-05 22.6 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EKX53178.1 - 9.4e-08 32.2 0.7 3.9e-05 23.9 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EKX53179.1 - 3.7e-16 59.0 1.9 3.7e-05 23.9 0.1 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX53179.1 - 6e-16 58.8 0.4 1e-15 58.0 0.3 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX53179.1 - 1.4e-13 51.0 0.5 7.4e-07 29.6 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX53179.1 - 3.7e-13 49.3 4.4 9.5e-05 22.7 0.0 3.5 3 1 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EKX53179.1 - 2.4e-11 42.8 0.4 5.5e-05 23.3 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat SnoaL_2 PF12680.7 EKX53180.1 - 6.3e-09 36.4 0.0 6.9e-09 36.3 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain NTF2 PF02136.20 EKX53180.1 - 0.00016 22.3 0.0 0.00019 22.0 0.0 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain SnoaL_3 PF13474.6 EKX53180.1 - 0.012 15.8 0.1 0.014 15.7 0.1 1.1 1 0 0 1 1 1 0 SnoaL-like domain SbcD_C PF12320.8 EKX53180.1 - 0.014 15.7 0.0 0.016 15.4 0.0 1.2 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain SnoaL PF07366.12 EKX53180.1 - 0.08 12.7 0.0 0.11 12.3 0.0 1.3 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase Thioredoxin PF00085.20 EKX53181.1 - 3e-11 43.2 0.0 5.6e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Ribonuc_red_lgC PF02867.15 EKX53182.1 - 2.7e-190 633.4 0.0 3.5e-190 633.0 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EKX53182.1 - 2.2e-23 82.1 0.0 4.7e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EKX53182.1 - 8.3e-15 55.1 0.0 2.7e-14 53.5 0.0 2.0 1 0 0 1 1 1 1 ATP cone domain Ly-6_related PF06579.12 EKX53182.1 - 0.0094 16.2 0.1 0.032 14.5 0.1 1.9 1 0 0 1 1 1 1 Caenorhabditis elegans ly-6-related protein Rho_N PF07498.12 EKX53182.1 - 0.18 11.8 0.0 0.94 9.5 0.0 2.2 3 0 0 3 3 3 0 Rho termination factor, N-terminal domain SNF2_N PF00176.23 EKX53183.1 - 2.1e-59 201.0 0.6 7.3e-59 199.2 0.0 2.1 2 1 1 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX53183.1 - 2.1e-16 60.3 0.0 4.7e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SAM_2 PF07647.17 EKX53184.1 - 2.1e-05 24.5 0.0 6.4e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EKX53184.1 - 0.00013 22.3 0.0 0.00036 20.9 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) HEAT PF02985.22 EKX53184.1 - 0.085 13.2 0.6 1.5 9.3 0.1 2.6 2 0 0 2 2 2 0 HEAT repeat zf-C3H1 PF10650.9 EKX53185.1 - 0.11 12.2 1.0 0.41 10.4 0.2 2.2 2 0 0 2 2 2 0 Putative zinc-finger domain SWI2_SNF2 PF18766.1 EKX53186.1 - 8.8e-17 61.5 0.0 3.2e-13 49.9 0.0 3.2 3 0 0 3 3 3 2 SWI2/SNF2 ATPase TFIIS_M PF07500.14 EKX53186.1 - 2.4e-16 60.2 0.0 6.2e-16 58.9 0.0 1.8 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain ResIII PF04851.15 EKX53186.1 - 3e-13 50.1 0.0 6.5e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Med26 PF08711.11 EKX53186.1 - 8.5e-09 35.3 0.1 3.1e-08 33.5 0.1 2.0 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DEAD PF00270.29 EKX53186.1 - 0.004 16.9 0.0 0.012 15.4 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Chloroa_b-bind PF00504.21 EKX53187.1 - 1.2e-06 29.2 0.0 2.1e-06 28.4 0.0 1.5 1 1 0 1 1 1 1 Chlorophyll A-B binding protein HTH_33 PF13592.6 EKX53188.1 - 0.067 12.8 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn helix zf-RING_2 PF13639.6 EKX53189.1 - 7.2e-11 42.2 6.0 7.2e-11 42.2 6.0 2.1 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EKX53189.1 - 5.7e-07 29.5 3.5 6.6e-07 29.3 1.9 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EKX53189.1 - 6e-07 29.7 7.5 6e-07 29.7 7.5 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EKX53189.1 - 1.2e-06 28.4 3.2 2.8e-06 27.2 3.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 EKX53189.1 - 1.7e-06 27.6 5.3 1.7e-06 27.6 5.3 2.0 2 0 0 2 2 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 EKX53189.1 - 2.5e-05 24.3 3.9 2.5e-05 24.3 3.9 1.8 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 EKX53189.1 - 3.3e-05 24.0 2.8 8.1e-05 22.7 2.8 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4 PF00097.25 EKX53189.1 - 0.00022 21.0 3.9 0.00058 19.7 3.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EKX53189.1 - 0.0016 18.2 8.1 0.0094 15.8 8.1 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EKX53189.1 - 0.0028 17.5 2.4 0.0072 16.2 2.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EKX53189.1 - 0.0062 16.1 7.2 0.028 14.0 7.3 2.1 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 EKX53189.1 - 0.03 14.5 3.6 0.1 12.7 3.6 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 EKX53189.1 - 0.041 13.8 10.5 0.032 14.2 7.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 HEAT_2 PF13646.6 EKX53189.1 - 0.045 14.2 0.7 6.7 7.2 0.0 3.6 2 2 3 5 5 5 0 HEAT repeats zf-C3HC4_5 PF17121.5 EKX53189.1 - 0.3 11.0 3.1 0.29 11.1 0.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 EKX53189.1 - 0.52 10.2 7.5 0.33 10.9 4.8 2.1 2 0 0 2 2 2 0 PHD-finger Prok-RING_4 PF14447.6 EKX53189.1 - 0.53 10.2 11.2 5.8 6.9 10.1 2.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Castor_Poll_mid PF06241.12 EKX53190.1 - 2e-16 59.9 0.0 3.8e-13 49.3 0.0 2.9 2 1 0 2 2 2 2 Castor and Pollux, part of voltage-gated ion channel TrkA_C PF02080.21 EKX53190.1 - 4.8e-07 29.5 0.0 4.3e-06 26.5 0.0 2.4 2 0 0 2 2 2 1 TrkA-C domain TrkA_N PF02254.18 EKX53190.1 - 0.065 13.5 0.0 0.25 11.6 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Castor_Poll_mid PF06241.12 EKX53191.1 - 1.9e-30 104.9 0.0 1.1e-27 96.0 0.0 3.1 3 1 0 3 3 3 2 Castor and Pollux, part of voltage-gated ion channel TrkA_C PF02080.21 EKX53191.1 - 0.0011 18.8 0.1 0.018 14.8 0.0 2.8 3 0 0 3 3 3 1 TrkA-C domain Beta_helix PF13229.6 EKX53192.1 - 1.2e-10 41.4 1.4 2.4e-09 37.2 1.2 2.5 2 1 0 2 2 2 1 Right handed beta helix region NosD PF05048.13 EKX53192.1 - 0.0014 18.0 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Adeno_E1B_55K PF01696.17 EKX53192.1 - 0.022 13.5 1.6 0.033 12.9 1.6 1.2 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen DUF1415 PF07209.12 EKX53193.1 - 1.3e-28 99.9 0.0 2.9e-14 53.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1415) IMS PF00817.20 EKX53194.1 - 5e-42 143.4 0.0 5.7e-42 143.2 0.0 1.0 1 0 0 1 1 1 1 impB/mucB/samB family PITH PF06201.13 EKX53195.1 - 3.8e-36 124.6 0.4 4.6e-36 124.3 0.4 1.1 1 0 0 1 1 1 1 PITH domain Sad1_UNC PF07738.13 EKX53195.1 - 0.042 13.9 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 Sad1 / UNC-like C-terminal DUF1295 PF06966.12 EKX53196.1 - 1.9e-50 171.6 1.0 2.3e-50 171.3 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 EKX53196.1 - 1.8e-05 25.1 0.9 0.00016 22.0 0.1 2.8 2 1 1 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 EKX53196.1 - 0.00017 21.6 0.4 0.00032 20.7 0.4 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ERG4_ERG24 PF01222.17 EKX53196.1 - 0.014 14.2 0.0 0.03 13.1 0.0 1.6 1 1 1 2 2 2 0 Ergosterol biosynthesis ERG4/ERG24 family Methyltransf_32 PF13679.6 EKX53197.1 - 7.9e-26 90.9 0.0 5e-25 88.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain ArAE_2_N PF10337.9 EKX53197.1 - 0.052 12.6 2.1 0.086 11.9 2.1 1.3 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal PEMT PF04191.13 EKX53197.1 - 0.45 10.9 3.8 0.79 10.2 3.8 1.3 1 0 0 1 1 1 0 Phospholipid methyltransferase Baculo_PEP_C PF04513.12 EKX53198.1 - 0.084 12.9 2.5 1.2 9.1 0.0 3.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Helitron_like_N PF14214.6 EKX53198.1 - 2.8 8.1 5.2 1.8 8.8 1.1 2.6 2 1 0 2 2 2 0 Helitron helicase-like domain at N-terminus Spc7 PF08317.11 EKX53200.1 - 2.3e-07 30.0 14.3 2.3e-07 30.0 14.3 3.7 3 2 0 3 3 3 1 Spc7 kinetochore protein Snapin_Pallidin PF14712.6 EKX53200.1 - 0.0015 18.9 3.1 0.0015 18.9 3.1 4.1 4 1 0 4 4 3 1 Snapin/Pallidin SYCE1 PF15233.6 EKX53200.1 - 0.0072 16.4 1.5 0.0072 16.4 1.5 4.3 3 1 1 4 4 4 1 Synaptonemal complex central element protein 1 PKcGMP_CC PF16808.5 EKX53200.1 - 0.032 14.1 1.9 0.032 14.1 1.9 4.3 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF2564 PF10819.8 EKX53200.1 - 0.41 11.1 11.0 0.94 9.9 0.2 4.4 3 1 0 4 4 4 0 Protein of unknown function (DUF2564) Golgin_A5 PF09787.9 EKX53200.1 - 3.6 7.0 51.1 0.032 13.7 10.8 4.2 2 2 1 4 4 4 0 Golgin subfamily A member 5 HALZ PF02183.18 EKX53200.1 - 4.4 7.6 14.1 0.75 10.1 0.2 4.8 4 1 1 5 5 5 0 Homeobox associated leucine zipper DUF4988 PF16378.5 EKX53200.1 - 6.6 6.4 8.3 0.45 10.2 0.2 2.9 4 0 0 4 4 4 0 Domain of unknown function Herpes_UL6 PF01763.16 EKX53200.1 - 6.7 5.1 16.6 0.12 10.9 4.9 2.5 2 1 0 2 2 2 0 Herpesvirus UL6 like Fez1 PF06818.15 EKX53200.1 - 8 6.9 48.8 0.45 10.9 14.2 3.7 1 1 1 3 3 3 0 Fez1 DUF1664 PF07889.12 EKX53200.1 - 9.5 6.3 25.9 0.33 11.0 3.9 4.6 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) RWP-RK PF02042.15 EKX53201.1 - 3.4e-16 58.9 0.1 6.5e-16 58.0 0.1 1.5 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX53202.1 - 4.2e-16 58.7 0.1 6.2e-16 58.1 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain DUF1232 PF06803.12 EKX53202.1 - 0.14 12.0 0.1 0.24 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1232) RWP-RK PF02042.15 EKX53203.1 - 3.7e-16 58.8 0.1 5.5e-16 58.3 0.1 1.3 1 0 0 1 1 1 1 RWP-RK domain DUF1232 PF06803.12 EKX53203.1 - 0.13 12.1 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1232) Golgin_A5 PF09787.9 EKX53204.1 - 0.00094 18.7 4.9 0.00094 18.7 4.9 2.0 1 1 1 2 2 2 1 Golgin subfamily A member 5 COG5 PF10392.9 EKX53204.1 - 0.0015 18.7 4.6 0.69 10.1 0.3 2.5 2 1 0 2 2 2 2 Golgi transport complex subunit 5 DHR10 PF18595.1 EKX53204.1 - 0.0065 16.5 29.4 0.18 11.9 4.5 3.9 1 1 2 3 3 3 3 Designed helical repeat protein 10 domain TPR_MLP1_2 PF07926.12 EKX53204.1 - 0.0078 16.3 2.7 0.0078 16.3 2.7 3.3 1 1 1 3 3 3 1 TPR/MLP1/MLP2-like protein ApoO PF09769.9 EKX53204.1 - 0.029 14.3 1.5 0.19 11.7 0.4 2.5 1 1 2 3 3 3 0 Apolipoprotein O Lzipper-MIP1 PF14389.6 EKX53204.1 - 0.038 14.3 1.9 0.038 14.3 1.9 3.0 3 1 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF1664 PF07889.12 EKX53204.1 - 0.046 13.7 10.2 2.5 8.1 3.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Hrs_helical PF12210.8 EKX53204.1 - 0.072 13.6 1.8 0.072 13.6 1.8 3.6 2 2 1 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Bap31_Bap29_C PF18035.1 EKX53204.1 - 0.074 13.1 4.6 0.22 11.5 0.0 3.3 3 1 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain Baculo_PEP_C PF04513.12 EKX53204.1 - 0.075 13.1 6.6 0.52 10.4 4.9 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3347 PF11827.8 EKX53204.1 - 0.077 13.2 6.2 0.11 12.6 5.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) Fez1 PF06818.15 EKX53204.1 - 0.12 12.8 19.7 0.021 15.3 4.5 2.2 1 1 1 2 2 2 0 Fez1 ADIP PF11559.8 EKX53204.1 - 0.13 12.4 20.1 0.21 11.7 7.3 2.6 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding CLZ PF16526.5 EKX53204.1 - 0.21 12.0 20.7 1.4 9.4 5.6 4.3 1 1 4 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PSI_PsaF PF02507.15 EKX53204.1 - 0.22 11.3 2.8 2.4 8.0 0.1 2.2 2 0 0 2 2 2 0 Photosystem I reaction centre subunit III Prominin PF05478.11 EKX53204.1 - 0.31 8.9 5.6 1.6 6.6 0.5 2.2 1 1 1 2 2 2 0 Prominin APG17 PF04108.12 EKX53204.1 - 0.31 10.1 14.2 0.56 9.3 9.2 2.4 2 1 0 2 2 2 0 Autophagy protein Apg17 IFT57 PF10498.9 EKX53204.1 - 0.35 9.8 11.3 0.08 11.9 7.8 1.7 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 NPV_P10 PF05531.12 EKX53204.1 - 0.36 11.3 4.0 13 6.3 0.3 2.8 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 EKX53204.1 - 0.57 10.6 7.6 18 5.8 0.1 4.1 2 2 1 4 4 2 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 EKX53204.1 - 0.63 8.9 19.0 0.91 8.3 5.5 2.7 1 1 2 3 3 3 0 Spc7 kinetochore protein MobC PF05713.11 EKX53204.1 - 0.71 10.4 4.7 0.5 10.9 0.6 2.8 3 0 0 3 3 2 0 Bacterial mobilisation protein (MobC) CorA PF01544.18 EKX53204.1 - 0.8 9.0 14.6 1.1 8.5 2.7 2.2 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Helo_like_N PF17111.5 EKX53204.1 - 1.1 8.6 14.2 1.3 8.4 5.6 3.0 2 1 0 2 2 2 0 Fungal N-terminal domain of STAND proteins LMBR1 PF04791.16 EKX53204.1 - 1.1 8.1 5.0 1.4 7.7 5.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Tho2 PF11262.8 EKX53204.1 - 1.4 8.1 8.0 1.5 8.0 6.7 1.7 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FH2 PF02181.23 EKX53204.1 - 1.4 8.0 8.9 1.5 7.9 4.2 2.2 1 1 1 2 2 2 0 Formin Homology 2 Domain MscS_porin PF12795.7 EKX53204.1 - 1.8 8.1 23.2 5.5 6.5 14.1 2.7 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Laminin_II PF06009.12 EKX53204.1 - 2.6 8.1 11.2 0.89 9.6 1.1 3.0 2 1 1 3 3 3 0 Laminin Domain II V_ATPase_I PF01496.19 EKX53204.1 - 4.3 5.1 10.4 5.1 4.9 8.5 1.7 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF4795 PF16043.5 EKX53204.1 - 4.5 6.8 15.9 13 5.4 15.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Fzo_mitofusin PF04799.13 EKX53204.1 - 4.5 6.8 13.0 4.9 6.7 0.8 2.8 2 1 1 3 3 3 0 fzo-like conserved region TMPIT PF07851.13 EKX53204.1 - 4.8 6.3 10.4 12 5.0 0.8 2.3 1 1 1 2 2 2 0 TMPIT-like protein Exonuc_VII_L PF02601.15 EKX53204.1 - 5.1 6.6 17.3 37 3.8 17.3 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit TMF_TATA_bd PF12325.8 EKX53204.1 - 6.7 7.0 22.5 5.3 7.3 1.4 3.4 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding OmpH PF03938.14 EKX53204.1 - 7.9 6.8 21.9 1.1e+04 -3.4 21.9 2.9 1 1 0 1 1 0 0 Outer membrane protein (OmpH-like) COG2 PF06148.11 EKX53204.1 - 8.6 6.5 14.2 35 4.5 4.5 3.9 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 GPHR_N PF12537.8 EKX53204.1 - 9.6 6.4 9.0 2.5 8.3 1.0 3.2 3 1 0 3 3 2 0 The Golgi pH Regulator (GPHR) Family N-terminal FliD_C PF07195.12 EKX53204.1 - 9.8 5.5 10.8 1.2 8.5 2.6 2.6 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus PLAT PF01477.23 EKX53205.1 - 2.1e-05 25.1 0.0 3.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 PLAT/LH2 domain DUF16 PF01519.16 EKX53205.1 - 0.088 13.3 0.2 0.16 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 Herpes_US12 PF05363.12 EKX53205.1 - 0.11 13.2 0.2 0.51 11.1 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus US12 family MRPL52 PF18699.1 EKX53205.1 - 0.52 10.5 2.8 1.7 8.9 2.8 1.9 1 0 0 1 1 1 0 Mitoribosomal protein mL52 LRR_4 PF12799.7 EKX53206.1 - 3.4e-13 49.5 2.5 1.6e-06 28.3 0.0 3.3 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX53206.1 - 3.8e-11 42.8 0.0 9.6e-11 41.5 0.0 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 EKX53206.1 - 3.3e-10 39.6 0.0 4e-08 32.9 0.0 3.2 2 1 1 3 3 3 1 Leucine rich repeat LRR_6 PF13516.6 EKX53206.1 - 0.047 13.8 0.1 39 4.6 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich repeat AnkUBD PF18418.1 EKX53207.1 - 6.9e-22 77.4 0.1 9.8e-06 25.6 0.0 4.4 4 0 0 4 4 4 4 Ankyrin ubiquitin-binding domain OTU PF02338.19 EKX53207.1 - 8.2e-16 58.7 0.0 1.5e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease ABC_membrane PF00664.23 EKX53208.1 - 3.8e-55 187.5 21.2 5.3e-55 187.0 21.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EKX53208.1 - 4.8e-33 114.6 0.0 1.4e-32 113.1 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EKX53208.1 - 8.9e-07 28.6 2.5 0.0016 17.9 2.5 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EKX53208.1 - 0.00082 19.1 0.3 0.0033 17.1 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EKX53208.1 - 0.0024 18.2 0.9 0.012 15.9 0.1 2.4 2 1 0 2 2 1 1 AAA domain AAA_30 PF13604.6 EKX53208.1 - 0.0067 16.2 2.2 0.016 14.9 0.3 2.5 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EKX53208.1 - 0.01 15.1 2.3 0.021 14.1 0.0 2.4 3 0 0 3 3 3 0 Zeta toxin AAA_16 PF13191.6 EKX53208.1 - 0.011 16.1 1.4 0.081 13.3 1.4 2.5 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EKX53208.1 - 0.018 15.4 0.2 0.4 11.1 0.2 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EKX53208.1 - 0.033 13.9 0.0 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EKX53208.1 - 0.036 14.0 0.0 0.093 12.6 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 EKX53208.1 - 0.037 13.8 0.0 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system IFT20 PF14931.6 EKX53208.1 - 0.078 13.2 2.5 0.24 11.6 2.5 1.8 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Rad17 PF03215.15 EKX53208.1 - 0.083 12.8 0.0 0.3 11.0 0.0 1.8 1 1 0 2 2 2 0 Rad17 P-loop domain ATP_bind_1 PF03029.17 EKX53208.1 - 0.094 12.5 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein SbcCD_C PF13558.6 EKX53208.1 - 0.13 12.5 0.2 0.83 9.9 0.2 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EKX53208.1 - 0.9 10.0 0.0 0.9 10.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain ADIP PF11559.8 EKX53208.1 - 2.4 8.3 8.7 0.035 14.2 1.4 1.6 2 0 0 2 2 1 0 Afadin- and alpha -actinin-Binding PCI PF01399.27 EKX53209.1 - 4.5e-15 56.0 0.0 1.7e-14 54.2 0.0 2.0 2 0 0 2 2 2 1 PCI domain Dehydrin PF00257.19 EKX53210.1 - 5.1 7.6 6.3 7 7.2 6.3 1.3 1 1 0 1 1 1 0 Dehydrin EamA PF00892.20 EKX53212.1 - 1.6e-06 28.3 6.6 1.6e-06 28.3 6.6 2.1 2 0 0 2 2 2 1 EamA-like transporter family TPT PF03151.16 EKX53212.1 - 0.0015 17.9 1.0 0.002 17.5 1.0 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family Ferlin_C PF16165.5 EKX53212.1 - 0.052 13.5 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 Ferlin C-terminus DUF4260 PF14079.6 EKX53212.1 - 0.1 12.6 2.6 0.23 11.4 2.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4260) Phage_Gp23 PF10669.9 EKX53212.1 - 0.21 12.0 2.5 0.83 10.0 1.7 2.2 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Laminin_G_3 PF13385.6 EKX53213.1 - 7.3e-10 39.2 0.3 2.3e-08 34.3 0.3 2.7 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily EPTP PF03736.17 EKX53213.1 - 1.6e-06 28.0 14.9 0.039 13.9 0.2 7.9 7 1 0 7 7 7 3 EPTP domain Zn-C2H2_12 PF18112.1 EKX53213.1 - 0.0031 17.9 0.0 0.013 16.0 0.0 2.2 1 0 0 1 1 1 1 Autophagy receptor zinc finger-C2H2 domain Lactonase PF10282.9 EKX53213.1 - 0.011 15.1 0.0 2.4 7.4 0.0 2.7 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller SGL PF08450.12 EKX53213.1 - 0.035 13.7 0.0 0.085 12.4 0.0 1.6 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region DUF5122 PF17164.4 EKX53213.1 - 0.043 14.1 1.2 6.8 7.1 0.1 4.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5122) beta-propeller TIG PF01833.24 EKX53213.1 - 0.077 13.1 1.3 1.4 9.1 0.0 4.0 3 0 0 3 3 3 0 IPT/TIG domain Big_9 PF17963.1 EKX53213.1 - 0.37 11.6 9.4 8.1 7.3 0.0 6.0 6 0 0 6 6 6 0 Bacterial Ig domain Kinesin PF00225.23 EKX53214.1 - 5.9e-109 364.0 0.1 7.1e-109 363.8 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX53214.1 - 1e-27 96.9 0.0 1.6e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding Sigma54_activat PF00158.26 EKX53214.1 - 0.055 13.2 0.0 8.7 6.0 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.16 EKX53214.1 - 0.086 12.3 0.1 0.18 11.2 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein Pkinase PF00069.25 EKX53215.1 - 1.7e-29 103.0 0.0 5.5e-28 98.1 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX53215.1 - 1.9e-13 50.3 0.0 5.6e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX53215.1 - 7.8e-06 25.4 0.3 1.8e-05 24.2 0.3 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EKX53215.1 - 0.00081 18.3 0.1 0.0022 16.8 0.1 1.7 1 0 0 1 1 1 1 Fungal protein kinase IBR PF01485.21 EKX53215.1 - 1 9.7 15.1 0.038 14.2 8.2 2.3 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain DIOX_N PF14226.6 EKX53216.1 - 3.1e-26 92.4 0.0 4.8e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EKX53216.1 - 5.9e-18 65.2 0.0 8.4e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rieske PF00355.26 EKX53217.1 - 3e-12 46.3 0.0 6.3e-12 45.3 0.0 1.5 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 EKX53217.1 - 2e-11 43.9 0.0 4.5e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Pheophorbide a oxygenase Metallophos_2 PF12850.7 EKX53218.1 - 0.04 14.1 0.0 0.1 12.8 0.0 1.7 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Ank_4 PF13637.6 EKX53219.1 - 8.2e-20 70.9 0.4 9.7e-07 29.2 0.2 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX53219.1 - 4.3e-17 62.5 0.0 4.4e-14 52.8 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX53219.1 - 3.8e-13 49.4 0.3 3.6e-08 33.5 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX53219.1 - 1.8e-12 46.3 0.0 0.00011 22.3 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EKX53219.1 - 5.4e-12 45.6 0.0 3.7e-06 27.1 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat DUF2634 PF10934.8 EKX53220.1 - 0.16 12.1 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2634) fn3 PF00041.21 EKX53221.1 - 0.00015 22.0 0.1 0.28 11.6 0.0 5.0 4 0 0 4 4 4 1 Fibronectin type III domain Adipokin_hormo PF06377.11 EKX53222.1 - 0.11 12.9 0.1 0.27 11.6 0.1 1.7 1 0 0 1 1 1 0 Adipokinetic hormone GHMP_kinases_N PF00288.26 EKX53223.1 - 7e-05 23.0 0.1 0.00014 22.0 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EKX53223.1 - 0.075 13.4 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 GHMP kinases C terminal CRT-like PF08627.10 EKX53224.1 - 2.4e-24 85.9 14.6 2.4e-19 69.5 4.3 2.0 1 1 1 2 2 2 2 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 EKX53224.1 - 2.5e-05 24.4 6.5 2.5e-05 24.4 6.5 3.1 3 0 0 3 3 3 1 EamA-like transporter family EmrE PF13536.6 EKX53224.1 - 0.014 15.0 6.2 0.015 14.9 5.8 1.5 1 1 0 1 1 1 0 Putative multidrug resistance efflux transporter Nuc_sug_transp PF04142.15 EKX53224.1 - 0.017 14.3 2.4 0.028 13.6 2.4 1.3 1 0 0 1 1 1 0 Nucleotide-sugar transporter PUNUT PF16913.5 EKX53224.1 - 0.11 11.7 12.7 0.73 9.0 4.3 2.3 1 1 1 2 2 2 0 Purine nucleobase transmembrane transport DUF373 PF04123.13 EKX53224.1 - 3.8 6.8 6.9 5.8 6.3 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) INT_SG_DDX_CT_C PF15300.6 EKX53225.1 - 0.1 12.4 0.7 0.18 11.6 0.4 1.6 1 1 1 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus WD40 PF00400.32 EKX53226.1 - 2.2e-21 75.7 8.1 2.1e-07 31.5 2.2 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX53226.1 - 1.9e-09 37.7 0.4 0.0089 16.3 0.1 4.5 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EKX53226.1 - 7.4e-05 22.7 0.1 0.1 12.7 0.0 3.5 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 EKX53226.1 - 0.00064 19.1 0.2 0.44 9.8 0.0 2.3 2 0 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 EKX53226.1 - 0.014 14.1 1.1 0.64 8.6 0.1 2.2 1 1 0 2 2 2 0 Nucleoporin Nup120/160 DUF2610 PF11020.8 EKX53226.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2610) MltA PF03562.17 EKX53226.1 - 0.23 11.2 0.0 0.36 10.6 0.0 1.2 1 0 0 1 1 1 0 MltA specific insert domain RtcB PF01139.17 EKX53228.1 - 3.3e-142 474.5 0.0 3.8e-142 474.3 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Cu-oxidase_4 PF02578.15 EKX53228.1 - 0.082 12.5 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Multi-copper polyphenol oxidoreductase laccase ACP_syn_III_C PF08541.10 EKX53228.1 - 0.086 13.0 0.1 0.25 11.5 0.1 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF412 PF04217.13 EKX53230.1 - 0.14 12.1 0.2 0.2 11.5 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function, DUF412 Mpv17_PMP22 PF04117.12 EKX53231.1 - 0.0002 21.5 0.1 0.00043 20.5 0.1 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Rootletin PF15035.6 EKX53231.1 - 0.0056 16.7 2.2 0.0093 16.0 2.2 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion HAUS-augmin3 PF14932.6 EKX53231.1 - 0.036 13.6 1.9 0.05 13.2 1.9 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Mg_chelatase_C PF13335.6 EKX53231.1 - 0.04 14.5 1.3 0.062 13.9 1.3 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal TAF1D PF15333.6 EKX53231.1 - 0.044 13.5 0.1 0.067 12.9 0.1 1.3 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D ZapB PF06005.12 EKX53231.1 - 0.046 14.2 0.9 0.082 13.4 0.9 1.3 1 0 0 1 1 1 0 Cell division protein ZapB PspB PF06667.12 EKX53231.1 - 3.5 7.8 4.9 0.68 10.0 0.8 1.8 2 0 0 2 2 2 0 Phage shock protein B Ldh_1_N PF00056.23 EKX53232.1 - 9.6e-33 113.2 0.0 1.7e-32 112.4 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EKX53232.1 - 9.7e-33 113.4 0.4 3e-32 111.8 0.2 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_3_C PF01915.22 EKX53232.1 - 0.0046 16.9 0.0 0.046 13.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain RBB1NT PF08169.11 EKX53232.1 - 0.044 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 RBB1NT (NUC162) domain C2 PF00168.30 EKX53233.1 - 0.022 15.0 0.0 2.1 8.7 0.0 3.3 2 1 0 2 2 2 0 C2 domain Ion_trans_2 PF07885.16 EKX53234.1 - 6.3e-12 45.3 11.7 6.3e-12 45.3 11.7 3.1 3 1 1 4 4 4 1 Ion channel EF-hand_5 PF13202.6 EKX53234.1 - 2.2e-08 33.2 2.4 0.028 13.9 0.1 4.6 5 0 0 5 5 5 2 EF hand EF-hand_1 PF00036.32 EKX53234.1 - 3e-08 32.6 3.5 0.14 11.8 0.0 4.8 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 EKX53234.1 - 3e-07 29.8 8.6 0.022 14.7 0.1 4.6 4 1 1 5 5 5 2 EF-hand domain Lig_chan PF00060.26 EKX53234.1 - 1.2e-06 28.4 0.5 3.2e-06 27.1 0.1 1.9 2 0 0 2 2 2 1 Ligand-gated ion channel EF-hand_7 PF13499.6 EKX53234.1 - 1.3e-06 28.7 7.3 0.0019 18.6 0.4 3.7 3 2 1 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX53234.1 - 5.2e-05 23.5 0.1 0.00018 21.8 0.1 1.9 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Ion_trans PF00520.31 EKX53234.1 - 0.00048 19.4 4.6 0.00048 19.4 4.6 1.9 2 0 0 2 2 2 1 Ion transport protein EF-hand_8 PF13833.6 EKX53234.1 - 0.0096 15.7 3.3 1.9 8.4 0.1 3.9 3 1 1 4 4 4 1 EF-hand domain pair TMEM154 PF15102.6 EKX53234.1 - 0.16 11.9 1.6 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 TMEM154 protein family Pex24p PF06398.11 EKX53234.1 - 0.23 10.4 3.4 0.18 10.8 0.1 2.0 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin LRR_4 PF12799.7 EKX53235.1 - 3.5e-26 90.8 46.7 1.5e-05 25.2 4.9 8.6 3 1 8 12 12 12 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX53235.1 - 2.1e-25 88.2 36.5 3e-09 36.5 5.2 6.5 4 2 2 7 7 7 6 Leucine rich repeat LRR_9 PF14580.6 EKX53235.1 - 4.1e-05 23.2 20.4 0.002 17.6 3.3 3.8 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 EKX53235.1 - 0.068 13.7 22.5 29 5.8 0.1 8.9 9 3 0 9 9 9 0 Leucine Rich Repeat RabGAP-TBC PF00566.18 EKX53236.1 - 2.2e-27 96.1 4.2 8.5e-27 94.2 4.2 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Nipped-B_C PF12830.7 EKX53237.1 - 9.7e-21 74.6 2.5 8.2e-18 65.0 0.9 3.8 3 2 0 3 3 3 2 Sister chromatid cohesion C-terminus Cnd1 PF12717.7 EKX53237.1 - 7e-07 29.4 3.0 1.2e-05 25.4 0.0 3.9 3 1 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 EKX53237.1 - 9e-07 29.1 0.6 0.00033 20.9 0.2 2.9 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.6 EKX53237.1 - 8e-06 26.2 0.3 0.0023 18.3 0.1 3.9 2 1 1 3 3 3 2 HEAT repeats Cnd3 PF12719.7 EKX53237.1 - 0.00046 19.5 1.5 0.65 9.1 0.0 3.1 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 EKX53237.1 - 0.022 15.0 9.4 19 5.8 0.0 6.5 7 0 0 7 7 7 0 HEAT repeat V-ATPase_H_C PF11698.8 EKX53237.1 - 0.028 14.5 1.6 1.6 8.8 0.1 3.6 3 0 0 3 3 3 0 V-ATPase subunit H RTC4 PF14474.6 EKX53237.1 - 0.034 14.3 0.3 0.74 10.0 0.3 2.8 2 0 0 2 2 2 0 RTC4-like domain TPR_1 PF00515.28 EKX53237.1 - 0.35 10.8 1.4 62 3.7 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat MTS PF05175.14 EKX53239.1 - 3.8e-17 62.4 1.0 6.4e-13 48.6 0.3 3.1 2 1 0 2 2 2 2 Methyltransferase small domain PrmA PF06325.13 EKX53239.1 - 4.5e-13 49.2 0.0 7.3e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EKX53239.1 - 6.4e-10 39.0 0.0 1.2e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX53239.1 - 8.1e-10 39.3 0.0 2.7e-09 37.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 EKX53239.1 - 3.9e-08 33.0 0.0 6.9e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 EKX53239.1 - 5.6e-06 26.2 0.1 9.1e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.18 EKX53239.1 - 1.1e-05 25.3 0.1 0.00024 20.8 0.1 2.7 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.6 EKX53239.1 - 1.5e-05 24.9 0.0 4e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EKX53239.1 - 1.8e-05 24.5 0.1 4.4e-05 23.2 0.1 1.6 1 1 0 1 1 1 1 Conserved hypothetical protein 95 N6_Mtase PF02384.16 EKX53239.1 - 2.2e-05 23.9 0.0 4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_11 PF08241.12 EKX53239.1 - 6.4e-05 23.5 0.3 0.00018 22.1 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EKX53239.1 - 0.00097 18.9 0.1 0.0031 17.3 0.0 1.8 2 0 0 2 2 2 1 Lysine methyltransferase tRNA_U5-meth_tr PF05958.11 EKX53239.1 - 0.0018 17.3 0.0 0.0027 16.8 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltr_RsmB-F PF01189.17 EKX53239.1 - 0.0027 17.4 0.0 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Ubie_methyltran PF01209.18 EKX53239.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TRM PF02005.16 EKX53239.1 - 0.017 14.3 0.0 0.049 12.8 0.0 1.7 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase RrnaAD PF00398.20 EKX53239.1 - 0.018 14.1 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 EKX53239.1 - 0.02 15.6 0.0 0.055 14.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain NADHdeh_related PF10125.9 EKX53239.1 - 0.15 11.4 0.1 0.51 9.7 0.1 1.7 2 0 0 2 2 2 0 NADH dehydrogenase I, subunit N related protein Pkinase_Tyr PF07714.17 EKX53241.1 - 1.9e-65 220.7 0.0 2.2e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX53241.1 - 3.5e-30 105.2 0.0 4.4e-30 104.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain RNase_H2-Ydr279 PF09468.10 EKX53245.1 - 1.2e-10 41.8 0.1 2.1e-10 41.0 0.1 1.5 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain TPR_2 PF07719.17 EKX53246.1 - 7.1e-22 75.7 0.1 4.2e-05 23.3 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 EKX53246.1 - 1.8e-21 74.9 0.1 0.00033 20.8 0.0 4.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 EKX53246.1 - 1.8e-18 66.6 0.8 1.2e-06 28.7 0.1 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX53246.1 - 4.1e-17 60.9 0.0 2.9e-05 23.9 0.0 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 EKX53246.1 - 1.8e-16 59.2 0.0 8.2e-06 25.4 0.0 4.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX53246.1 - 3.5e-14 51.7 0.8 0.014 15.4 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX53246.1 - 3.5e-14 52.1 1.3 0.0099 15.7 0.0 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 EKX53246.1 - 1.1e-13 51.4 0.1 0.0015 19.0 0.0 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX53246.1 - 4.1e-13 49.0 0.8 0.0087 16.8 0.0 4.4 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX53246.1 - 1.6e-11 44.6 1.5 9.1e-05 23.0 0.0 3.5 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX53246.1 - 7e-09 35.2 0.0 0.0036 17.0 0.0 4.4 4 1 1 5 5 5 2 TPR repeat ANAPC3 PF12895.7 EKX53246.1 - 8e-08 32.4 1.9 0.0017 18.6 0.5 2.3 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 EKX53246.1 - 1.9e-05 24.5 0.0 0.0066 16.4 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX53246.1 - 5e-05 22.8 0.2 0.0061 16.0 0.0 2.4 1 1 1 2 2 2 2 MalT-like TPR region Coatomer_E PF04733.14 EKX53246.1 - 0.00051 19.5 0.0 0.022 14.2 0.0 2.4 1 1 2 3 3 3 1 Coatomer epsilon subunit TPR_9 PF13371.6 EKX53246.1 - 0.00053 20.1 0.0 0.056 13.6 0.0 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 EKX53246.1 - 0.00079 19.8 0.0 10 7.1 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 EKX53246.1 - 0.00092 18.5 0.1 0.09 12.0 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX53246.1 - 0.0013 19.2 0.7 12 6.7 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat NARP1 PF12569.8 EKX53246.1 - 0.013 14.4 0.0 1.8 7.4 0.0 1.8 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 EKX53246.1 - 0.014 15.7 0.0 4.5 7.7 0.0 2.8 1 1 2 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 EKX53246.1 - 0.022 15.0 1.1 18 5.9 0.0 4.0 4 0 0 4 4 4 0 PPR repeat ImpA_N PF06812.12 EKX53246.1 - 0.057 13.5 0.7 0.11 12.6 0.1 1.7 2 0 0 2 2 2 0 ImpA, N-terminal, type VI secretion system Fis1_TPR_C PF14853.6 EKX53246.1 - 0.064 13.3 0.2 4.8 7.3 0.0 2.8 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat phiKZ_IP PF12699.7 EKX53246.1 - 0.16 11.1 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 phiKZ-like phage internal head proteins PPR_1 PF12854.7 EKX53246.1 - 0.47 10.2 2.1 6 6.7 0.0 3.4 4 0 0 4 4 4 0 PPR repeat LMBR1 PF04791.16 EKX53248.1 - 3.1e-35 122.1 11.9 7.9e-32 110.8 11.9 3.5 1 1 0 1 1 1 1 LMBR1-like membrane protein Pkinase PF00069.25 EKX53249.1 - 6.9e-55 186.3 0.0 8.5e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX53249.1 - 1.4e-33 116.2 0.0 1.9e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX53249.1 - 0.0055 16.1 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EKX53249.1 - 0.0086 15.2 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 EKX53249.1 - 0.01 15.8 0.0 0.023 14.6 0.0 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX53249.1 - 0.021 13.6 0.0 0.029 13.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EKX53249.1 - 0.2 10.6 0.0 0.33 9.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Speriolin_N PF15058.6 EKX53250.1 - 0.36 10.9 11.6 1.7 8.7 2.2 3.1 3 0 0 3 3 3 0 Speriolin N terminus PDZ PF00595.24 EKX53251.1 - 1e-07 32.2 0.0 2.5e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX53251.1 - 1e-05 25.2 0.0 2.8e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX53251.1 - 0.0018 18.6 0.0 0.004 17.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX53251.1 - 0.0045 16.9 0.0 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 Tricorn protease PDZ domain TMCO5 PF14992.6 EKX53251.1 - 0.012 15.2 18.9 0.016 14.8 18.9 1.1 1 0 0 1 1 1 0 TMCO5 family Spc7 PF08317.11 EKX53251.1 - 0.024 13.5 19.0 0.033 13.1 19.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Pox_A_type_inc PF04508.12 EKX53251.1 - 0.024 14.5 0.1 0.074 12.9 0.1 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat AAA_23 PF13476.6 EKX53251.1 - 0.039 14.5 10.0 0.053 14.0 10.0 1.2 1 0 0 1 1 1 0 AAA domain APG6_N PF17675.1 EKX53251.1 - 0.056 14.0 26.0 0.21 12.1 16.0 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region ADIP PF11559.8 EKX53251.1 - 0.07 13.2 21.5 0.24 11.5 6.4 2.7 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.12 EKX53251.1 - 0.077 13.1 19.0 1.4 9.0 7.8 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CCDC-167 PF15188.6 EKX53251.1 - 0.081 13.3 17.4 0.025 14.9 10.3 2.7 1 1 1 2 2 1 0 Coiled-coil domain-containing protein 167 Ax_dynein_light PF10211.9 EKX53251.1 - 0.13 12.2 19.9 0.056 13.4 5.5 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain GIT1_C PF12205.8 EKX53251.1 - 0.15 12.2 11.9 0.061 13.4 3.3 2.2 1 1 1 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF724 PF05266.14 EKX53251.1 - 0.17 11.7 16.8 0.16 11.8 4.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) ATG16 PF08614.11 EKX53251.1 - 0.17 12.1 21.1 2.5 8.3 21.1 2.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Nsp1_C PF05064.13 EKX53251.1 - 0.19 11.5 13.4 0.041 13.7 4.5 2.4 1 1 0 2 2 2 0 Nsp1-like C-terminal region GCN5L1 PF06320.13 EKX53251.1 - 0.22 11.7 12.9 0.14 12.3 6.8 2.3 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) Cep57_CLD PF14073.6 EKX53251.1 - 0.35 10.9 20.0 0.19 11.7 16.6 2.2 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 AAA_15 PF13175.6 EKX53251.1 - 0.36 10.5 9.2 0.45 10.2 9.2 1.1 1 0 0 1 1 1 0 AAA ATPase domain Fez1 PF06818.15 EKX53251.1 - 0.37 11.2 17.8 0.46 10.9 17.2 1.4 1 1 0 1 1 1 0 Fez1 AAA_31 PF13614.6 EKX53251.1 - 0.64 9.9 4.7 0.74 9.7 3.4 1.6 1 1 0 1 1 1 0 AAA domain JAKMIP_CC3 PF16034.5 EKX53251.1 - 1 9.3 20.1 5.4 6.9 7.9 2.4 1 1 1 2 2 2 0 JAKMIP CC3 domain HAP1_N PF04849.13 EKX53251.1 - 1.3 8.1 23.7 2.6 7.2 23.5 1.4 1 1 0 1 1 1 0 HAP1 N-terminal conserved region DUF4600 PF15372.6 EKX53251.1 - 1.4 9.3 16.6 1.7 9.1 12.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) DUF4472 PF14739.6 EKX53251.1 - 1.8 9.4 21.5 0.52 11.1 2.8 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4472) SlyX PF04102.12 EKX53251.1 - 3.8 8.2 12.0 6.2 7.5 3.7 2.5 1 1 1 2 2 2 0 SlyX DUF4407 PF14362.6 EKX53251.1 - 3.9 6.7 8.8 6.1 6.1 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 EKX53251.1 - 4.2 7.5 12.2 6.6 6.9 12.2 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Plk4_PB2 PF18409.1 EKX53251.1 - 4.3 8.0 8.1 7.5 7.3 2.1 2.5 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 DUF1664 PF07889.12 EKX53251.1 - 4.5 7.3 8.3 5.9 6.9 5.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) YabA PF06156.13 EKX53251.1 - 4.7 7.9 18.6 0.87 10.3 6.3 2.6 1 1 2 3 3 3 0 Initiation control protein YabA MCU PF04678.13 EKX53251.1 - 7.7 6.6 11.5 2.6 8.1 3.9 2.1 1 1 1 2 2 2 0 Mitochondrial calcium uniporter DUF3450 PF11932.8 EKX53251.1 - 9.1 5.5 16.7 9.6 5.4 3.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Bap31_Bap29_C PF18035.1 EKX53252.1 - 7.2e-05 22.7 25.6 1.5 8.9 0.1 8.4 7 0 0 7 7 7 4 Bap31/Bap29 cytoplasmic coiled-coil domain PI3K_P85_iSH2 PF16454.5 EKX53252.1 - 0.00056 19.6 8.9 0.00056 19.6 8.9 11.9 6 3 3 9 9 9 2 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4598 PF15370.6 EKX53252.1 - 0.013 16.0 0.8 0.013 16.0 0.8 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4598) E2R135 PF11570.8 EKX53252.1 - 0.14 12.4 2.7 8.6 6.7 0.5 4.6 3 0 0 3 3 3 0 Coiled-coil receptor-binding R-domain of colicin E2 TTL PF03133.15 EKX53253.1 - 2.6e-49 167.9 0.2 1.6e-48 165.3 0.2 1.8 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EKX53253.1 - 1.5e-07 30.9 0.1 0.009 15.3 0.0 3.2 2 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EKX53253.1 - 6.7e-07 28.8 0.0 0.0033 16.7 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EKX53253.1 - 0.029 14.4 0.0 0.94 9.5 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain Cwf_Cwc_15 PF04889.12 EKX53253.1 - 0.056 13.2 5.1 0.08 12.7 5.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein HTH_30 PF13556.6 EKX53253.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain DNA_pol_phi PF04931.13 EKX53253.1 - 0.67 8.0 4.7 0.86 7.6 4.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 EKX53253.1 - 0.77 9.0 4.4 1.1 8.5 4.4 1.1 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 EKX53253.1 - 1.3 9.5 10.2 2.3 8.6 10.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3598 PF12204.8 EKX53254.1 - 0.00025 20.7 0.2 0.69 9.4 0.0 3.3 2 2 1 3 3 3 3 Domain of unknown function (DUF3598) EPL1 PF10513.9 EKX53255.1 - 3.4e-12 47.0 3.5 3.4e-12 47.0 3.5 2.5 2 1 0 2 2 2 1 Enhancer of polycomb-like UPF0561 PF10573.9 EKX53255.1 - 4.7 7.4 7.8 1.1 9.4 0.0 3.5 4 0 0 4 4 4 0 Uncharacterised protein family UPF0561 LRR_8 PF13855.6 EKX53256.1 - 3.4e-13 49.1 11.4 1.1e-07 31.5 1.2 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EKX53256.1 - 1.7e-09 37.8 8.0 1.3e-05 25.4 1.2 3.2 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EKX53256.1 - 0.078 13.1 7.3 0.68 10.1 0.0 4.4 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 EKX53256.1 - 0.19 12.4 9.5 23 6.0 0.6 4.9 4 1 0 4 4 4 0 Leucine Rich Repeat PKD_channel PF08016.12 EKX53257.1 - 3.3e-25 88.7 11.1 7.7e-11 41.3 7.2 3.2 1 1 2 3 3 3 3 Polycystin cation channel Ion_trans PF00520.31 EKX53257.1 - 4.2e-05 22.9 6.0 4.2e-05 22.9 6.0 1.6 2 0 0 2 2 2 1 Ion transport protein Ank_5 PF13857.6 EKX53258.1 - 4.5e-07 30.0 0.1 9.6e-07 29.0 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX53258.1 - 9.7e-06 26.0 0.1 4.3e-05 24.0 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX53258.1 - 1.1e-05 25.9 0.0 2.8e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX53258.1 - 0.0015 18.9 0.0 0.0062 16.9 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 EKX53258.1 - 0.0031 17.9 0.1 0.01 16.3 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeat IQ PF00612.27 EKX53258.1 - 0.46 10.4 22.5 0.12 12.2 1.2 4.9 4 0 0 4 4 4 0 IQ calmodulin-binding motif TPR_17 PF13431.6 EKX53260.1 - 1.3e-17 62.8 10.3 0.0024 18.1 0.1 5.2 5 0 0 5 5 4 4 Tetratricopeptide repeat Ank_5 PF13857.6 EKX53260.1 - 6.3e-13 48.7 0.1 2.4e-12 46.8 0.1 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX53260.1 - 1.5e-12 47.9 0.1 6.8e-12 45.8 0.1 2.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX53260.1 - 1.1e-11 45.0 0.6 1.7e-06 28.5 0.1 3.2 2 2 2 4 4 3 2 Ankyrin repeats (many copies) TPR_8 PF13181.6 EKX53260.1 - 1.8e-11 43.3 11.0 0.0095 16.1 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX53260.1 - 1.1e-10 41.4 7.3 0.12 13.2 0.1 5.8 2 1 4 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX53260.1 - 1.2e-10 41.9 9.2 0.00045 20.8 1.9 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX53260.1 - 6.6e-10 38.4 17.7 0.028 14.2 0.7 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX53260.1 - 2.1e-09 36.9 11.0 0.0063 16.2 0.7 4.6 2 1 2 4 4 4 4 TPR repeat TPR_12 PF13424.6 EKX53260.1 - 2.6e-09 37.2 15.4 0.0002 21.6 3.3 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX53260.1 - 5.9e-09 35.4 19.2 0.024 14.8 1.4 6.1 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 EKX53260.1 - 2.3e-08 34.4 14.8 0.001 19.5 2.1 5.0 4 1 2 6 6 5 3 Tetratricopeptide repeat Ank PF00023.30 EKX53260.1 - 7.9e-08 32.4 0.7 4.8e-05 23.6 0.3 3.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EKX53260.1 - 1.3e-07 31.4 1.1 0.00042 20.5 0.1 3.9 4 0 0 4 4 2 1 Ankyrin repeat TPR_7 PF13176.6 EKX53260.1 - 3.4e-06 26.7 7.1 0.59 10.3 0.0 4.7 5 0 0 5 5 4 3 Tetratricopeptide repeat TPPII_N PF12583.8 EKX53260.1 - 0.00048 20.7 3.8 0.16 12.6 0.2 3.3 3 1 0 3 3 3 1 Tripeptidyl peptidase II N terminal Coatomer_E PF04733.14 EKX53260.1 - 0.0038 16.7 5.1 7.7 5.8 0.4 3.8 1 1 3 4 4 4 0 Coatomer epsilon subunit TPR_9 PF13371.6 EKX53260.1 - 0.0066 16.6 5.0 0.3 11.3 0.1 4.2 2 1 2 4 4 4 1 Tetratricopeptide repeat Tcf25 PF04910.14 EKX53260.1 - 0.0075 15.4 1.4 1.9 7.4 0.0 3.0 1 1 1 3 3 3 1 Transcriptional repressor TCF25 TSNAXIP1_N PF15739.5 EKX53260.1 - 0.035 14.5 0.0 0.13 12.6 0.1 1.9 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus TPR_3 PF07720.12 EKX53260.1 - 0.32 11.0 13.1 1.9 8.6 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX53260.1 - 0.34 10.9 11.4 3.7 7.5 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX53260.1 - 1.5 9.1 8.4 32 4.9 6.6 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EKX53260.1 - 1.6 9.5 9.5 35 5.3 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat AA_kinase PF00696.28 EKX53261.1 - 2e-41 142.2 0.7 2.5e-41 141.9 0.7 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 EKX53261.1 - 3.7e-06 26.8 0.1 2.2e-05 24.3 0.1 2.4 1 0 0 1 1 1 1 PUA domain LEA_3 PF03242.13 EKX53263.1 - 0.19 12.5 3.1 0.97 10.2 0.1 2.3 2 0 0 2 2 2 0 Late embryogenesis abundant protein TraL PF07178.11 EKX53263.1 - 1.5 9.3 3.8 1.3 9.6 2.4 1.6 2 0 0 2 2 2 0 TraL protein Nop PF01798.18 EKX53264.1 - 6.9e-67 225.3 0.1 1.1e-66 224.7 0.1 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 EKX53264.1 - 1.2e-27 97.3 6.4 3.1e-27 95.9 6.4 1.7 1 0 0 1 1 1 1 Prp31 C terminal domain Imm-NTF2 PF15655.6 EKX53264.1 - 0.15 12.3 0.9 1.7 8.9 0.5 2.2 2 0 0 2 2 2 0 NTF2 fold immunity protein DUF1257 PF06868.11 EKX53264.1 - 0.19 12.0 0.7 6.8 7.0 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1257) SM-ATX PF14438.6 EKX53265.1 - 0.037 14.2 0.0 0.066 13.4 0.0 1.5 1 1 0 1 1 1 0 Ataxin 2 SM domain LSM14 PF12701.7 EKX53265.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Scd6-like Sm domain Dynactin_p62 PF05502.13 EKX53265.1 - 0.36 9.6 3.3 0.45 9.2 3.3 1.1 1 0 0 1 1 1 0 Dynactin p62 family Paf1 PF03985.13 EKX53265.1 - 0.93 8.4 15.3 0.94 8.4 15.3 1.2 1 0 0 1 1 1 0 Paf1 CobT PF06213.12 EKX53265.1 - 4.8 6.5 16.6 6.4 6.1 16.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT COPI_C PF06957.11 EKX53265.1 - 6.6 5.4 8.2 7.5 5.2 8.2 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus ERp29 PF07749.12 EKX53266.1 - 0.08 13.8 2.8 0.12 13.3 2.8 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain HI0933_like PF03486.14 EKX53266.1 - 0.1 11.3 0.4 0.12 11.0 0.4 1.0 1 0 0 1 1 1 0 HI0933-like protein PRTase_1 PF11202.8 EKX53266.1 - 0.15 11.3 0.8 0.21 10.8 0.8 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase (PRTase) DUF2368 PF10166.9 EKX53266.1 - 1.2 8.7 6.6 2.5 7.7 6.6 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) SAE2 PF08573.10 EKX53266.1 - 4.5 8.4 8.2 78 4.4 8.7 2.0 1 1 1 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Ran_BP1 PF00638.18 EKX53268.1 - 1.8e-14 54.1 5.1 1.4e-06 28.6 0.1 3.8 3 1 1 4 4 4 3 RanBP1 domain NUP50 PF08911.11 EKX53268.1 - 2.5e-08 34.5 18.9 2.5e-08 34.5 18.9 3.6 3 1 0 3 3 3 1 NUP50 (Nucleoporin 50 kDa) Ribosomal_60s PF00428.19 EKX53269.1 - 0.015 15.8 4.0 0.015 15.8 4.0 2.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein NADPH_Ox PF08414.10 EKX53269.1 - 0.043 14.1 0.7 0.043 14.1 0.7 2.0 2 1 0 2 2 2 0 Respiratory burst NADPH oxidase DUF3399 PF11879.8 EKX53269.1 - 6.4 7.2 9.8 2.1 8.7 2.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3399) TRM PF02005.16 EKX53270.1 - 3.3e-125 418.2 0.0 3.8e-125 418.0 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 EKX53270.1 - 1.1e-05 25.3 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 EKX53270.1 - 0.00037 20.2 0.0 0.0006 19.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 EKX53270.1 - 0.019 15.7 0.1 0.036 14.8 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EKX53270.1 - 0.029 13.8 0.3 0.045 13.2 0.3 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EKX53270.1 - 0.033 13.7 0.1 0.061 12.9 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain CaMBD PF02888.16 EKX53270.1 - 0.048 13.8 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 Calmodulin binding domain Methyltransf_31 PF13847.6 EKX53270.1 - 0.059 13.2 0.1 0.093 12.5 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain SPRY PF00622.28 EKX53272.1 - 0.021 14.9 0.0 0.052 13.7 0.0 1.7 1 1 0 1 1 1 0 SPRY domain Collagen PF01391.18 EKX53272.1 - 0.13 12.1 4.0 0.074 12.8 1.3 1.8 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) AdoHcyase_NAD PF00670.21 EKX53272.1 - 0.13 12.3 0.2 0.22 11.6 0.2 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Collagen PF01391.18 EKX53273.1 - 2.5e-12 46.4 61.8 1.7e-08 34.1 30.9 2.6 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) WW PF00397.26 EKX53273.1 - 5.3e-08 32.8 3.2 1.1e-07 31.8 3.2 1.6 1 0 0 1 1 1 1 WW domain BDV_P24 PF06595.11 EKX53273.1 - 0.057 13.3 0.6 4 7.3 0.0 2.5 2 0 0 2 2 2 0 Borna disease virus P24 protein GAS PF13851.6 EKX53276.1 - 0.002 17.5 0.6 0.002 17.5 0.6 2.0 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding WD40_alt PF14077.6 EKX53276.1 - 0.012 15.5 1.3 0.053 13.4 0.5 2.2 2 0 0 2 2 2 0 Alternative WD40 repeat motif ATG16 PF08614.11 EKX53276.1 - 0.046 13.9 8.4 0.1 12.8 3.7 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Rootletin PF15035.6 EKX53276.1 - 0.12 12.3 5.1 0.17 11.9 0.8 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DivIC PF04977.15 EKX53276.1 - 0.24 11.2 5.4 10 6.0 0.3 3.2 2 1 1 3 3 3 0 Septum formation initiator PRKG1_interact PF15898.5 EKX53276.1 - 2.3 9.1 10.0 2.9 8.8 5.3 2.4 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF4660 PF15559.6 EKX53277.1 - 0.0021 18.3 9.2 0.0039 17.5 9.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4660) SspB PF04386.13 EKX53277.1 - 1.7 8.5 5.6 2.2 8.1 4.8 1.7 1 1 0 1 1 1 0 Stringent starvation protein B CAP_GLY PF01302.25 EKX53278.1 - 4.9e-20 71.3 3.2 8.3e-20 70.6 3.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 EKX53278.1 - 9.2e-13 48.2 12.6 0.00018 21.8 1.6 4.4 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX53278.1 - 6.4e-10 38.7 15.1 2.7e-06 27.0 6.9 4.1 3 1 1 4 4 4 2 Leucine rich repeat LRR_9 PF14580.6 EKX53278.1 - 3.9e-09 36.2 4.6 3e-05 23.6 0.2 3.2 1 1 3 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 EKX53278.1 - 4.3e-05 23.2 2.1 3.7 7.8 0.0 5.4 5 0 0 5 5 5 1 Leucine Rich repeat Ubiquitin_2 PF14560.6 EKX53278.1 - 0.0035 17.7 0.1 0.01 16.2 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-like domain LRR_1 PF00560.33 EKX53278.1 - 0.012 16.1 3.6 59 4.8 0.2 5.3 6 0 0 6 6 6 0 Leucine Rich Repeat ABC_tran PF00005.27 EKX53279.1 - 5.8e-31 107.8 0.0 9.3e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EKX53279.1 - 6.6e-06 26.1 0.1 0.0065 16.3 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EKX53279.1 - 0.00032 20.2 0.1 0.003 17.0 0.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EKX53279.1 - 0.0023 17.9 0.3 0.0054 16.7 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase IstB_IS21 PF01695.17 EKX53279.1 - 0.0043 16.8 0.3 1.1 8.9 0.0 2.2 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_29 PF13555.6 EKX53279.1 - 0.0044 16.7 0.2 0.0094 15.7 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 EKX53279.1 - 0.0062 16.7 1.4 0.17 12.1 0.3 2.6 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 EKX53279.1 - 0.018 14.6 0.3 0.3 10.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EKX53279.1 - 0.018 15.4 0.1 0.028 14.8 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EKX53279.1 - 0.019 15.2 0.8 0.88 9.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain PIN_4 PF13638.6 EKX53279.1 - 0.055 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 PIN domain AAA_23 PF13476.6 EKX53279.1 - 0.23 12.0 0.2 0.39 11.2 0.2 1.3 1 0 0 1 1 1 0 AAA domain UPF0054 PF02130.17 EKX53280.1 - 6e-37 126.3 0.1 7.7e-37 126.0 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 EamA PF00892.20 EKX53281.1 - 1.1e-10 41.8 20.9 3.8e-07 30.3 5.6 2.7 2 1 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 EKX53281.1 - 1.2e-08 34.3 5.7 1.2e-08 34.3 5.7 2.1 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 EKX53281.1 - 1.8e-06 27.4 7.9 3.6e-06 26.4 7.6 1.8 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 EKX53281.1 - 1.4e-05 24.4 12.3 1.8e-05 24.1 12.3 1.1 1 0 0 1 1 1 1 UAA transporter family SLC35F PF06027.12 EKX53281.1 - 5.1e-05 22.9 5.9 5.1e-05 22.9 5.9 2.2 2 1 1 3 3 3 1 Solute carrier family 35 TPT PF03151.16 EKX53281.1 - 0.13 11.6 12.2 0.27 10.5 12.2 1.5 1 1 0 1 1 1 0 Triose-phosphate Transporter family TMEM234 PF10639.9 EKX53281.1 - 0.41 10.7 9.0 0.12 12.4 2.7 2.5 2 0 0 2 2 2 0 Putative transmembrane family 234 NUC153 PF08159.12 EKX53283.1 - 5.3e-13 48.5 1.0 1.2e-12 47.4 1.0 1.6 1 0 0 1 1 1 1 NUC153 domain ANAPC4_WD40 PF12894.7 EKX53283.1 - 0.071 13.4 0.0 3.9 7.8 0.0 3.7 3 2 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain PHINT_rpt PF14882.6 EKX53284.1 - 0.039 14.2 0.1 0.11 12.8 0.1 1.7 1 0 0 1 1 1 0 Phage-integrase repeat unit Collagen PF01391.18 EKX53285.1 - 0.0084 15.8 8.6 0.0084 15.8 8.6 2.0 2 0 0 2 2 2 1 Collagen triple helix repeat (20 copies) Trm112p PF03966.16 EKX53286.1 - 2.3e-10 40.9 0.0 4.5e-10 39.9 0.0 1.5 1 1 0 1 1 1 1 Trm112p-like protein Peptidase_M16_C PF05193.21 EKX53287.1 - 1.9e-35 122.5 0.0 1e-18 68.0 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EKX53287.1 - 3.9e-25 88.6 1.8 4.8e-20 72.0 0.0 3.2 3 0 0 3 3 3 2 Insulinase (Peptidase family M16) MPS2 PF17060.5 EKX53288.1 - 0.076 12.3 0.3 0.14 11.4 0.3 1.4 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF1192 PF06698.11 EKX53288.1 - 1.1 9.4 9.6 0.23 11.6 3.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) LRR_4 PF12799.7 EKX53289.1 - 1.2e-07 31.9 8.1 1.6e-05 25.2 1.9 3.3 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX53289.1 - 1.1e-06 28.3 6.8 0.00039 20.1 2.6 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_9 PF14580.6 EKX53289.1 - 2.1e-06 27.4 1.0 4.1e-06 26.4 1.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 EKX53289.1 - 0.2 11.8 3.1 28 5.1 0.4 3.4 3 0 0 3 3 3 0 Leucine Rich repeat CorA PF01544.18 EKX53290.1 - 0.4 9.9 0.7 7 5.9 0.0 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Myb_DNA-binding PF00249.31 EKX53291.1 - 4.9e-08 33.0 0.0 7.4e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX53291.1 - 0.00056 20.1 0.0 0.00086 19.5 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EKX53291.1 - 0.0056 16.6 0.0 0.0072 16.2 0.0 1.3 1 1 0 1 1 1 1 Myb DNA-binding like Pkinase PF00069.25 EKX53292.1 - 3.1e-40 138.2 0.0 3.7e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX53292.1 - 1.1e-16 60.9 0.0 1.3e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX53292.1 - 0.0005 19.5 0.2 0.00067 19.1 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EKX53292.1 - 0.056 12.8 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like ABC1 PF03109.16 EKX53292.1 - 0.13 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 ABC1 family Peptidase_C54 PF03416.19 EKX53294.1 - 4.3e-38 131.3 0.0 6.2e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C54 PH PF00169.29 EKX53294.1 - 1.2e-08 35.4 0.2 2.9e-08 34.2 0.2 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EKX53294.1 - 0.075 13.5 0.4 0.15 12.5 0.4 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Ras PF00071.22 EKX53295.1 - 3.2e-67 225.2 1.0 3.7e-67 225.0 1.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EKX53295.1 - 1.3e-37 128.6 0.2 2.1e-37 128.0 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EKX53295.1 - 8.4e-17 61.2 0.2 1e-16 60.9 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EKX53295.1 - 1.1e-06 28.6 0.6 0.016 15.1 0.1 2.3 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EKX53295.1 - 1.3e-05 24.7 0.1 1.5e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EKX53295.1 - 2.1e-05 24.5 0.1 4e-05 23.7 0.1 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EKX53295.1 - 3.8e-05 23.3 0.7 6.8e-05 22.5 0.3 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EKX53295.1 - 5.1e-05 22.8 0.0 7.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EKX53295.1 - 0.0017 17.9 0.1 0.012 15.2 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA PF00004.29 EKX53295.1 - 0.0021 18.5 0.0 0.31 11.4 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EKX53295.1 - 0.012 15.2 0.0 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 EKX53295.1 - 0.03 14.8 0.1 0.059 13.9 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 EKX53295.1 - 0.034 14.5 0.0 0.041 14.3 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EKX53295.1 - 0.045 13.5 0.0 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Dioxygenase_N PF04444.14 EKX53295.1 - 0.045 13.6 0.1 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 Catechol dioxygenase N terminus LANC_like PF05147.13 EKX53295.1 - 0.052 12.1 0.1 0.1 11.2 0.0 1.4 2 0 0 2 2 2 0 Lanthionine synthetase C-like protein AAA_22 PF13401.6 EKX53295.1 - 0.052 13.8 0.0 0.13 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EKX53295.1 - 0.058 13.4 0.0 0.098 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TniB PF05621.11 EKX53295.1 - 0.087 12.2 0.0 0.34 10.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein Spc7 PF08317.11 EKX53296.1 - 0.00026 20.0 9.1 0.00026 20.0 9.1 1.8 2 0 0 2 2 2 1 Spc7 kinetochore protein Cactin_mid PF10312.9 EKX53296.1 - 0.0043 16.8 3.6 0.0043 16.8 3.6 1.8 2 0 0 2 2 2 1 Conserved mid region of cactin Atg14 PF10186.9 EKX53296.1 - 0.0056 15.8 6.5 0.0056 15.8 6.5 1.4 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 WEMBL PF05701.11 EKX53296.1 - 0.006 15.3 13.3 0.026 13.3 10.4 2.0 2 0 0 2 2 2 1 Weak chloroplast movement under blue light Laminin_II PF06009.12 EKX53296.1 - 0.0088 16.1 9.7 0.093 12.7 8.3 2.2 2 0 0 2 2 2 1 Laminin Domain II CCM2_C PF16545.5 EKX53296.1 - 0.0093 16.5 2.1 0.0097 16.4 0.1 1.9 2 0 0 2 2 2 1 Cerebral cavernous malformation protein, harmonin-homology GAS PF13851.6 EKX53296.1 - 0.01 15.2 15.1 0.01 15.2 15.1 1.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3573 PF12097.8 EKX53296.1 - 0.041 12.7 1.2 0.054 12.3 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) GARP PF16731.5 EKX53296.1 - 0.046 13.4 7.1 0.26 10.9 5.5 2.1 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma DUF1151 PF06625.11 EKX53296.1 - 0.051 13.5 11.0 0.13 12.2 11.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) PKcGMP_CC PF16808.5 EKX53296.1 - 0.051 13.4 0.6 0.16 11.8 0.6 1.8 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Hemagglutinin PF00509.18 EKX53296.1 - 0.065 11.6 1.1 3.5 5.9 1.1 2.0 2 0 0 2 2 2 0 Haemagglutinin APG6_N PF17675.1 EKX53296.1 - 0.2 12.2 17.2 0.053 14.1 13.3 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region HrpB7 PF09486.10 EKX53296.1 - 0.23 11.8 13.9 0.13 12.6 9.9 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) SOBP PF15279.6 EKX53296.1 - 0.39 11.3 8.6 0.52 10.9 8.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein CAP59_mtransfer PF11735.8 EKX53296.1 - 0.53 9.9 4.1 0.87 9.2 4.1 1.3 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 TMF_TATA_bd PF12325.8 EKX53296.1 - 0.63 10.3 15.1 1.4 9.2 3.7 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Filament PF00038.21 EKX53296.1 - 0.65 9.5 17.9 0.097 12.2 12.9 1.8 2 0 0 2 2 2 0 Intermediate filament protein DUF4407 PF14362.6 EKX53296.1 - 0.75 9.1 7.9 0.14 11.5 4.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Perilipin PF03036.16 EKX53296.1 - 0.78 8.7 12.3 1.4 7.9 12.3 1.3 1 0 0 1 1 1 0 Perilipin family V_ATPase_I PF01496.19 EKX53296.1 - 0.93 7.3 9.2 0.27 9.1 6.0 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF948 PF06103.11 EKX53296.1 - 1 9.7 4.9 3.2 8.1 2.6 2.6 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 EKX53296.1 - 2.2 8.5 14.2 2.9 8.0 10.8 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 EKX53296.1 - 2.2 8.3 10.0 2 8.5 5.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 EKX53296.1 - 2.8 7.1 12.9 0.73 9.0 8.2 1.9 2 0 0 2 2 2 0 TMPIT-like protein CENP-F_leu_zip PF10473.9 EKX53296.1 - 4.1 7.4 17.4 0.59 10.2 13.5 1.5 2 0 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_GP20 PF06810.11 EKX53296.1 - 4.1 7.2 11.4 2.5 7.9 8.6 2.0 2 1 0 2 2 2 0 Phage minor structural protein GP20 Seryl_tRNA_N PF02403.22 EKX53296.1 - 4.9 7.4 13.6 15 5.9 4.5 3.1 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain OmpH PF03938.14 EKX53296.1 - 5.2 7.4 21.7 10 6.5 14.1 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Prominin PF05478.11 EKX53296.1 - 5.8 4.7 10.0 14 3.4 0.0 2.0 2 0 0 2 2 2 0 Prominin Fmp27_WPPW PF10359.9 EKX53296.1 - 7 5.4 13.1 21 3.8 13.1 1.8 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Exonuc_VII_L PF02601.15 EKX53296.1 - 7.1 6.1 17.4 0.68 9.5 11.9 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit FapA PF03961.13 EKX53296.1 - 7.1 5.1 8.3 2.9 6.4 6.0 1.4 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF724 PF05266.14 EKX53296.1 - 8.3 6.2 14.1 1.9 8.2 10.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF3450 PF11932.8 EKX53296.1 - 9.7 5.4 19.0 4.7 6.4 14.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) UPF0242 PF06785.11 EKX53296.1 - 9.8 6.2 16.6 2.7 8.0 12.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Glyco_transf_41 PF13844.6 EKX53297.1 - 8.3e-64 215.7 1.6 1.9e-32 112.4 0.4 2.8 2 1 0 2 2 2 2 Glycosyl transferase family 41 TPR_11 PF13414.6 EKX53297.1 - 1.3e-08 34.4 0.1 0.00022 20.8 0.0 3.5 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.17 EKX53297.1 - 2.1e-05 24.3 0.4 9.3 6.6 0.1 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX53297.1 - 0.00014 21.5 0.0 34 4.5 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 EKX53297.1 - 0.00036 21.1 5.8 1.1 10.0 1.9 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX53297.1 - 0.00051 20.1 0.2 1.3 9.4 0.2 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX53297.1 - 0.0052 17.5 8.5 0.51 11.3 0.3 4.6 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX53297.1 - 0.013 15.8 3.5 3.7 7.9 0.1 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 EKX53297.1 - 0.094 13.1 0.1 2.7 8.6 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 EKX53298.1 - 9.6e-131 436.9 0.0 1.4e-130 436.3 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 EKX53298.1 - 4.1e-128 427.6 0.0 6e-128 427.0 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 EKX53298.1 - 6.7e-42 140.7 13.5 3.8e-07 30.7 0.2 7.7 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX53298.1 - 5.5e-10 39.4 1.6 0.00039 20.6 0.1 5.5 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Fis1_TPR_C PF14853.6 EKX53298.1 - 0.03 14.4 0.1 0.073 13.2 0.1 1.6 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Nucleoporin_N PF08801.11 EKX53298.1 - 0.13 10.9 0.1 8 5.1 0.0 3.3 3 1 1 4 4 4 0 Nup133 N terminal like Nup160 PF11715.8 EKX53298.1 - 0.13 10.8 0.2 1.1 7.8 0.0 2.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Glyco_transf_15 PF01793.16 EKX53299.1 - 2.2e-25 89.6 2.2 3e-24 85.9 2.2 2.7 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase TPR_2 PF07719.17 EKX53299.1 - 1.5e-12 46.6 1.0 0.003 17.6 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX53299.1 - 1.7e-09 37.0 1.3 0.0019 18.1 0.0 5.0 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX53299.1 - 3.8e-09 36.0 0.0 0.0032 17.2 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX53299.1 - 9.2e-09 35.5 5.6 1.8e-05 25.0 0.1 5.2 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX53299.1 - 6.1e-08 32.3 8.2 0.0084 16.0 0.1 5.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 EKX53299.1 - 2.1e-07 30.9 1.1 0.13 12.9 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX53299.1 - 4.9e-06 26.3 0.1 0.029 14.6 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX53299.1 - 7.3e-05 23.3 8.5 1.7 9.7 0.1 6.0 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX53299.1 - 0.00024 21.7 6.8 0.34 11.6 0.4 3.8 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EKX53299.1 - 0.00027 21.4 0.5 0.068 13.7 0.0 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX53299.1 - 0.0053 17.3 0.9 2.8 8.8 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX53299.1 - 0.016 15.4 0.0 0.11 12.7 0.0 2.4 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EKX53299.1 - 0.11 13.0 0.1 39 5.0 0.0 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat IQ PF00612.27 EKX53300.1 - 0.0051 16.5 3.7 2.2 8.3 0.6 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif YlbD_coat PF14071.6 EKX53300.1 - 0.0054 17.0 0.1 0.0054 17.0 0.1 2.2 3 0 0 3 3 3 1 Putative coat protein PAS_4 PF08448.10 EKX53300.1 - 0.21 11.8 1.0 1.2 9.4 0.1 2.2 2 0 0 2 2 2 0 PAS fold DNA_pol_B PF00136.21 EKX53301.1 - 3.2e-119 398.6 0.3 4.2e-119 398.3 0.3 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EKX53301.1 - 4.6e-59 200.2 0.1 6.4e-59 199.8 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain RNase_H_2 PF13482.6 EKX53301.1 - 3.4e-06 27.1 0.6 1.3e-05 25.3 0.2 2.2 2 1 0 2 2 2 1 RNase_H superfamily DNA_pol_B_2 PF03175.13 EKX53301.1 - 7e-05 21.9 1.5 0.00013 21.0 0.2 2.1 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_A_exo1 PF01612.20 EKX53301.1 - 0.018 14.7 0.2 0.048 13.4 0.2 1.7 1 1 0 1 1 1 0 3'-5' exonuclease MORN PF02493.20 EKX53302.1 - 3.7e-13 48.5 25.5 2.6e-06 27.0 2.2 5.4 5 0 0 5 5 5 4 MORN repeat PARP PF00644.20 EKX53302.1 - 0.00013 21.6 0.4 0.0012 18.5 0.4 2.1 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Ank_2 PF12796.7 EKX53303.1 - 1.9e-08 34.8 0.0 3.8e-08 33.8 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX53303.1 - 5.7e-08 32.9 1.1 3.3e-05 24.1 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EKX53303.1 - 1.6e-07 31.1 0.1 0.0014 18.9 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EKX53303.1 - 2.5e-05 24.5 0.0 0.00072 19.8 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX53303.1 - 3.4e-05 24.3 0.2 0.0045 17.5 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) HEAT_2 PF13646.6 EKX53304.1 - 5.6e-21 74.7 16.3 2.6e-10 40.5 1.4 4.8 2 2 3 5 5 5 4 HEAT repeats HEAT PF02985.22 EKX53304.1 - 1.6e-13 49.6 9.6 0.001 19.2 0.0 7.9 7 1 0 7 7 7 2 HEAT repeat RTP1_C1 PF10363.9 EKX53304.1 - 8.7e-11 42.0 0.6 0.0085 16.3 0.0 4.3 1 1 2 3 3 3 3 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 EKX53304.1 - 1.2e-07 30.7 0.1 1e-06 27.7 0.1 2.1 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EKX53304.1 - 9.3e-05 22.5 0.1 1.5 8.9 0.0 3.2 1 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 EKX53304.1 - 0.0042 17.6 18.4 3.1 8.8 0.1 7.3 8 2 0 8 8 6 1 PBS lyase HEAT-like repeat Tti2 PF10521.9 EKX53304.1 - 0.0051 16.4 0.0 0.019 14.5 0.0 2.0 2 1 0 2 2 2 1 Tti2 family RasGEF_N_2 PF14663.6 EKX53304.1 - 0.009 16.4 0.4 22 5.5 0.0 4.0 2 2 2 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Arm PF00514.23 EKX53304.1 - 0.0099 15.9 3.3 34 4.7 0.0 5.5 6 1 1 7 7 7 0 Armadillo/beta-catenin-like repeat DUF2017 PF09438.10 EKX53304.1 - 0.016 15.1 0.8 0.03 14.2 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2017) HEAT_EZ PF13513.6 EKX53304.1 - 0.018 15.6 9.6 1.1 9.8 0.2 5.4 4 1 3 7 7 7 0 HEAT-like repeat DUF3385 PF11865.8 EKX53304.1 - 0.1 12.5 0.1 72 3.2 0.0 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF3385) Ank_5 PF13857.6 EKX53304.1 - 0.13 12.7 0.0 0.34 11.3 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF5578 PF17741.1 EKX53304.1 - 0.13 11.6 0.7 2.2 7.7 0.0 2.7 2 2 1 3 3 3 0 Family of unknown function (DUF5578) API5 PF05918.11 EKX53304.1 - 1.9 7.2 6.7 4.4 6.0 0.0 2.9 1 1 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) RNA_pol_Rpb2_3 PF04565.16 EKX53305.1 - 0.23 11.7 0.3 0.35 11.1 0.3 1.5 1 1 0 1 1 1 0 RNA polymerase Rpb2, domain 3 Acid_PPase PF12689.7 EKX53306.1 - 2.5 7.9 6.2 1.5 8.7 4.1 1.8 1 1 1 2 2 2 0 Acid Phosphatase LAGLIDADG_1 PF00961.19 EKX53306.1 - 5.9 7.9 8.3 22 6.1 0.9 2.6 1 1 1 2 2 2 0 LAGLIDADG endonuclease HMGL-like PF00682.19 EKX53307.1 - 2e-46 158.7 0.0 2.7e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 EKX53307.1 - 1.8e-17 63.5 0.0 4e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain HEAT_2 PF13646.6 EKX53308.1 - 2.9e-20 72.4 3.3 4.1e-05 23.9 0.0 4.7 3 1 1 4 4 4 4 HEAT repeats C2 PF00168.30 EKX53308.1 - 5.8e-18 65.1 0.0 1.8e-17 63.5 0.0 1.9 1 0 0 1 1 1 1 C2 domain HEAT PF02985.22 EKX53308.1 - 1.9e-12 46.3 5.5 0.24 11.8 0.1 7.6 7 1 1 8 8 8 3 HEAT repeat Cnd1 PF12717.7 EKX53308.1 - 1.8e-11 44.3 4.3 0.012 15.7 0.0 4.1 4 0 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EKX53308.1 - 1.3e-09 37.2 2.9 1.2e-06 27.4 1.9 2.8 1 1 0 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.6 EKX53308.1 - 1.2e-05 25.7 0.8 0.13 12.8 0.0 5.1 5 0 0 5 5 5 1 HEAT-like repeat LZ3wCH PF18517.1 EKX53308.1 - 0.031 14.4 0.2 0.089 12.9 0.2 1.8 1 0 0 1 1 1 0 Leucine zipper with capping helix domain ABC_tran_Xtn PF12848.7 EKX53308.1 - 0.055 13.5 0.1 0.26 11.4 0.1 2.2 1 0 0 1 1 1 0 ABC transporter HHH_3 PF12836.7 EKX53309.1 - 3e-08 33.8 0.0 6e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif PsbU PF06514.11 EKX53309.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Photosystem II 12 kDa extrinsic protein (PsbU) RsmJ PF04378.13 EKX53310.1 - 1.7e-24 86.4 0.1 6.2e-13 48.5 0.0 3.1 1 1 2 3 3 3 3 Ribosomal RNA large subunit methyltransferase D, RlmJ Nudc_N PF14050.6 EKX53311.1 - 4.5e-21 74.6 0.0 7.5e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.16 EKX53311.1 - 5e-13 49.9 0.2 8.3e-13 49.2 0.2 1.4 1 0 0 1 1 1 1 CS domain LSM PF01423.22 EKX53313.1 - 7.1e-15 54.4 0.3 1e-14 54.0 0.3 1.2 1 0 0 1 1 1 1 LSM domain zf-Tim10_DDP PF02953.15 EKX53315.1 - 9.7e-18 63.6 3.1 1.4e-17 63.0 3.1 1.4 1 1 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 EKX53315.1 - 0.003 17.3 5.2 0.0087 15.7 4.9 1.7 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) DUF2116 PF09889.9 EKX53315.1 - 0.024 14.6 2.0 0.13 12.2 0.1 2.3 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Catalase-rel PF06628.12 EKX53315.1 - 0.059 13.6 0.3 0.11 12.7 0.3 1.5 1 0 0 1 1 1 0 Catalase-related immune-responsive MORN PF02493.20 EKX53316.1 - 2.8e-30 102.4 71.7 0.0007 19.3 0.0 13.0 12 1 0 12 12 12 10 MORN repeat DSPc PF00782.20 EKX53319.1 - 6.8e-29 100.4 0.0 8.6e-29 100.0 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX53319.1 - 0.026 14.1 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX53319.1 - 0.12 12.5 0.1 0.25 11.4 0.1 1.5 2 0 0 2 2 2 0 Inositol hexakisphosphate TPR_20 PF14561.6 EKX53320.1 - 0.0002 21.6 2.2 5.2 7.5 0.0 5.1 4 1 0 4 4 4 2 Tetratricopeptide repeat DUF1697 PF08002.11 EKX53320.1 - 0.024 15.1 2.3 0.12 12.8 0.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1697) DUF1843 PF08898.10 EKX53320.1 - 0.74 10.4 4.4 4.2 7.9 0.3 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Glyco_transf_20 PF00982.21 EKX53322.1 - 1.7e-105 353.5 0.0 2.8e-105 352.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EKX53322.1 - 2.7e-34 118.3 0.0 5.1e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase CBM_20 PF00686.19 EKX53322.1 - 1.2e-20 73.2 0.1 3.3e-20 71.8 0.1 1.8 1 0 0 1 1 1 1 Starch binding domain DMT_6 PF04342.12 EKX53323.1 - 2.8e-31 107.8 7.6 3.3e-31 107.6 7.6 1.1 1 0 0 1 1 1 1 Putative member of DMT superfamily (DUF486) EamA PF00892.20 EKX53323.1 - 0.16 12.2 12.5 5.1 7.3 12.5 2.1 1 1 0 1 1 1 0 EamA-like transporter family DUF202 PF02656.15 EKX53323.1 - 0.4 11.2 7.6 0.94 10.0 1.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF202) COX4_pro PF03626.14 EKX53323.1 - 2.3 8.7 9.8 0.14 12.6 1.9 2.3 2 1 0 2 2 2 0 Prokaryotic Cytochrome C oxidase subunit IV Mito_carr PF00153.27 EKX53324.1 - 1.1e-20 73.3 5.6 4.9e-07 29.6 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PseudoU_synth_1 PF01416.20 EKX53325.1 - 0.068 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 tRNA pseudouridine synthase DUF1216 PF06746.11 EKX53325.1 - 0.084 12.9 1.2 0.11 12.4 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) PDZ PF00595.24 EKX53327.1 - 6.9e-10 39.1 1.4 1.2e-09 38.3 1.4 1.5 1 1 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX53327.1 - 6.8e-09 35.4 0.1 1.5e-08 34.4 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX53327.1 - 7.8e-08 32.5 0.3 1.2e-07 31.9 0.3 1.3 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX53327.1 - 0.004 17.1 0.2 0.012 15.5 0.0 1.8 1 1 1 2 2 2 1 Tricorn protease PDZ domain Biotin_lipoyl_2 PF13533.6 EKX53327.1 - 0.043 13.6 0.1 0.095 12.5 0.1 1.5 1 0 0 1 1 1 0 Biotin-lipoyl like PDZ_1 PF12812.7 EKX53327.1 - 0.056 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 PDZ-like domain Ank_2 PF12796.7 EKX53328.1 - 8.1e-37 125.7 8.1 3.4e-12 46.8 0.5 2.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX53328.1 - 6.9e-27 93.5 3.0 2.1e-08 34.5 0.1 4.1 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX53328.1 - 1.2e-22 77.6 0.3 0.0016 18.8 0.0 5.2 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 EKX53328.1 - 1.1e-19 70.2 4.1 0.00026 21.2 0.0 4.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EKX53328.1 - 6.4e-18 64.3 1.1 0.00076 19.8 0.1 5.1 5 0 0 5 5 5 5 Ankyrin repeat UIM PF02809.20 EKX53330.1 - 0.0012 18.7 1.4 0.0047 16.7 1.4 2.2 1 0 0 1 1 1 1 Ubiquitin interaction motif UBA_e1_thiolCys PF10585.9 EKX53330.1 - 0.12 12.3 0.1 0.12 12.3 0.1 1.8 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site IFP_35_N PF07334.13 EKX53331.1 - 0.24 11.5 4.8 5.1 7.2 0.2 3.5 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus KxDL PF10241.9 EKX53331.1 - 1.1 9.5 9.5 1.1 9.5 7.4 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein MRP-S31 PF15433.6 EKX53331.1 - 1.7 8.3 12.2 2.4 7.8 12.2 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF5401 PF17380.2 EKX53331.1 - 2.2 6.2 13.6 2.9 5.9 13.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) SlyX PF04102.12 EKX53331.1 - 2.7 8.7 7.7 3.2 8.5 0.7 3.1 1 1 1 2 2 2 0 SlyX TSC22 PF01166.18 EKX53332.1 - 1.1 9.7 7.7 0.64 10.4 4.6 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family HAUS6_N PF14661.6 EKX53332.1 - 3.6 7.1 12.1 2.4 7.7 10.3 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Thioredoxin PF00085.20 EKX53333.1 - 0.0012 18.8 0.0 0.0017 18.3 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin Cementoin PF10511.9 EKX53333.1 - 0.34 11.3 1.3 6.7 7.2 0.2 2.2 2 0 0 2 2 2 0 Trappin protein transglutaminase binding domain TPR_8 PF13181.6 EKX53334.1 - 2.5e-14 52.2 10.4 0.00025 21.0 0.0 5.7 6 0 0 6 6 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 EKX53334.1 - 2.2e-13 49.2 11.1 0.033 14.3 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EKX53334.1 - 3.9e-12 46.5 3.1 0.013 16.0 0.0 4.6 4 1 1 5 5 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 EKX53334.1 - 1e-11 44.6 1.5 0.0071 17.1 0.0 5.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX53334.1 - 1.9e-11 44.4 0.1 0.018 15.7 0.0 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX53334.1 - 1.5e-09 37.2 8.0 0.042 13.7 0.0 6.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX53334.1 - 3.4e-08 33.6 4.1 0.004 17.4 0.1 4.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 EKX53334.1 - 5.4e-06 26.7 2.1 0.25 12.1 0.0 5.3 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX53334.1 - 7.1e-06 25.7 2.7 0.74 10.0 0.1 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX53334.1 - 1.1e-05 25.6 6.1 0.15 12.3 0.2 3.7 3 0 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EKX53334.1 - 0.00014 22.0 0.0 0.013 15.6 0.0 3.0 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX53334.1 - 0.0015 18.2 2.0 0.58 9.9 0.1 4.3 4 1 1 5 5 5 1 TPR repeat TPR_10 PF13374.6 EKX53334.1 - 0.0019 18.0 3.0 8.6 6.4 0.0 4.4 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX53334.1 - 0.0026 18.0 0.3 11 6.7 0.1 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX53334.1 - 0.0084 16.2 0.0 6.1 7.0 0.0 3.1 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_21 PF09976.9 EKX53334.1 - 0.011 15.4 1.9 8.7 6.0 0.0 3.4 2 1 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 EKX53334.1 - 0.083 12.3 5.1 0.86 8.9 0.2 3.5 3 1 1 4 4 4 0 MalT-like TPR region Coatomer_E PF04733.14 EKX53334.1 - 0.13 11.7 2.8 0.39 10.1 0.0 2.9 4 1 1 5 5 5 0 Coatomer epsilon subunit CCDC-167 PF15188.6 EKX53334.1 - 0.31 11.4 5.1 0.47 10.8 0.1 3.1 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 COPI_assoc PF08507.10 EKX53335.1 - 3.8e-13 49.6 9.3 1.7e-10 41.1 3.8 2.1 2 0 0 2 2 2 2 COPI associated protein DUF202 PF02656.15 EKX53335.1 - 0.013 15.9 2.0 0.076 13.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) YIEGIA PF14045.6 EKX53335.1 - 0.067 12.0 0.2 0.11 11.3 0.2 1.3 1 0 0 1 1 1 0 YIEGIA protein Delta_lysin PF05372.11 EKX53335.1 - 2 7.8 3.7 0.63 9.4 0.1 1.9 2 0 0 2 2 2 0 Delta lysin family FHA PF00498.26 EKX53336.1 - 3e-06 27.5 0.0 5.2e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EKX53336.1 - 8.2e-05 22.9 0.0 0.00015 22.0 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain WD40 PF00400.32 EKX53337.1 - 4.6e-12 46.2 24.6 0.0079 17.0 0.1 10.5 11 0 0 11 11 11 3 WD domain, G-beta repeat HEAT PF02985.22 EKX53337.1 - 2.1e-05 24.4 1.1 0.0083 16.3 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat Nup160 PF11715.8 EKX53337.1 - 2.3e-05 23.2 4.0 0.49 9.0 0.1 4.9 4 1 1 5 5 5 3 Nucleoporin Nup120/160 HEAT_2 PF13646.6 EKX53337.1 - 5.8e-05 23.4 1.0 0.15 12.4 0.0 3.1 2 1 1 3 3 3 3 HEAT repeats ANAPC4_WD40 PF12894.7 EKX53337.1 - 7.1e-05 23.0 1.2 5.7 7.3 0.0 5.8 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain HEAT_EZ PF13513.6 EKX53337.1 - 0.00032 21.1 0.4 0.035 14.6 0.0 3.0 1 1 1 2 2 2 1 HEAT-like repeat Hira PF07569.11 EKX53337.1 - 0.016 15.0 0.1 0.098 12.4 0.1 2.3 2 0 0 2 2 2 0 TUP1-like enhancer of split MtN3_slv PF03083.16 EKX53338.1 - 1.1e-40 137.6 12.5 1.3e-21 76.4 2.9 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange EcKinase PF02958.20 EKX53339.1 - 2e-11 43.7 0.0 2.5e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 EKX53339.1 - 6.2e-11 41.8 0.0 6.9e-11 41.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.23 EKX53339.1 - 8.6e-11 42.2 0.9 1.2e-10 41.7 0.9 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Filamin PF00630.19 EKX53340.1 - 9.9e-108 354.0 0.5 8e-18 65.2 0.0 7.2 7 0 0 7 7 7 7 Filamin/ABP280 repeat Invasin_D3 PF09134.10 EKX53340.1 - 2.3e-25 88.7 0.0 0.001 19.3 0.0 7.0 7 0 0 7 7 7 5 Invasin, domain 3 Neurexophilin PF06312.12 EKX53340.1 - 4e-09 36.3 0.1 0.0094 15.4 0.0 4.9 5 0 0 5 5 5 3 Neurexophilin YtkA PF13115.6 EKX53340.1 - 1.5e-08 35.1 1.5 0.55 10.9 0.0 6.9 7 0 0 7 7 7 1 YtkA-like Cadherin_5 PF17892.1 EKX53340.1 - 1.8e-07 31.0 0.4 2.3 8.3 0.0 5.7 6 0 0 6 6 6 1 Cadherin-like domain Y_Y_Y PF07495.13 EKX53340.1 - 3e-06 27.1 1.5 2.3 8.2 0.0 5.7 7 0 0 7 7 7 2 Y_Y_Y domain Big_3_5 PF16640.5 EKX53340.1 - 1.7e-05 24.9 0.7 3.6 7.8 0.0 5.5 6 0 0 6 6 6 1 Bacterial Ig-like domain (group 3) FixH PF05751.11 EKX53340.1 - 4.9e-05 23.4 0.1 4.4 7.3 0.0 5.2 5 0 0 5 5 5 1 FixH CopC PF04234.12 EKX53340.1 - 0.00024 22.1 0.7 17 6.5 0.0 5.0 7 0 0 7 7 5 0 CopC domain DUF5011 PF16403.5 EKX53340.1 - 0.044 13.9 7.9 0.62 10.2 0.1 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF5011) Big_8 PF17961.1 EKX53340.1 - 0.15 12.2 0.2 18 5.5 0.0 4.0 5 0 0 5 5 5 0 Bacterial Ig domain FlgD_ig PF13860.6 EKX53340.1 - 0.58 10.1 11.8 62 3.6 0.1 6.7 8 1 1 9 9 9 0 FlgD Ig-like domain MFS_1 PF07690.16 EKX53341.1 - 3.8e-22 78.7 52.6 6.5e-21 74.6 41.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CrgA PF06781.12 EKX53341.1 - 0.22 11.6 5.3 4.7 7.3 0.0 3.7 3 1 1 4 4 4 0 Cell division protein CrgA GDI PF00996.18 EKX53343.1 - 2.1e-38 132.0 0.0 1.9e-24 86.0 0.0 3.0 3 0 0 3 3 3 3 GDP dissociation inhibitor TBCC PF07986.12 EKX53344.1 - 1.3e-34 118.5 0.0 1.9e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 EKX53344.1 - 5e-07 30.2 0.1 8.8e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain PseudoU_synth_2 PF00849.22 EKX53345.1 - 5e-25 88.4 0.0 7.2e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF2773 PF10971.8 EKX53345.1 - 0.12 12.5 0.1 0.3 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) RNase_T PF00929.24 EKX53346.1 - 3.3e-09 37.5 0.0 1.3e-07 32.3 0.0 2.4 1 1 1 2 2 2 1 Exonuclease PolyA_pol_RNAbd PF12627.7 EKX53346.1 - 4.7e-09 35.9 0.2 1.4e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 EKX53346.1 - 7.4e-06 26.0 0.0 1.5e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative EF-hand_1 PF00036.32 EKX53347.1 - 5.2e-06 25.6 0.0 4.4e-05 22.7 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EKX53347.1 - 2.7e-05 23.9 0.0 0.00037 20.3 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 EKX53347.1 - 0.00021 21.7 0.7 0.04 14.4 0.1 3.6 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX53347.1 - 0.00032 20.1 0.1 0.0015 18.0 0.1 2.3 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EKX53347.1 - 0.0014 18.4 0.0 0.017 15.0 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain RRN9 PF10680.9 EKX53347.1 - 0.1 12.9 0.2 0.6 10.4 0.2 2.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor Peptidase_S46 PF10459.9 EKX53347.1 - 2.6 6.6 23.3 3.8 6.0 23.3 1.3 1 0 0 1 1 1 0 Peptidase S46 ApoO PF09769.9 EKX53347.1 - 2.6 8.0 6.8 0.65 10.0 1.4 2.5 1 1 1 2 2 2 0 Apolipoprotein O Baculo_PEP_C PF04513.12 EKX53347.1 - 3.7 7.6 11.3 0.24 11.4 1.2 2.6 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc29 PF17082.5 EKX53347.1 - 4.1 7.2 17.7 0.067 13.0 3.9 3.0 1 1 2 3 3 3 0 Spindle Pole Component 29 DUF1664 PF07889.12 EKX53347.1 - 7.8 6.6 23.1 1.1 9.3 4.8 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Pkinase PF00069.25 EKX53348.1 - 4.8e-69 232.7 0.0 5.4e-69 232.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX53348.1 - 2.2e-46 158.2 0.0 2.7e-46 158.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX53348.1 - 0.00031 20.1 0.1 0.17 11.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like PglD_N PF17836.1 EKX53348.1 - 0.11 13.2 0.0 0.2 12.3 0.0 1.3 1 0 0 1 1 1 0 PglD N-terminal domain TPR_1 PF00515.28 EKX53349.1 - 7.3e-11 41.4 2.7 3e-06 26.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX53349.1 - 7.2e-10 38.3 1.4 0.00016 21.6 0.0 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX53349.1 - 2.4e-09 36.6 2.0 1.3e-05 24.9 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX53349.1 - 0.00016 22.1 2.0 0.0019 18.7 0.1 3.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX53349.1 - 0.00017 21.7 1.4 0.0023 18.2 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX53349.1 - 0.00039 21.0 0.3 0.41 11.6 0.0 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX53349.1 - 0.00092 19.3 0.0 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX53349.1 - 0.0011 19.4 0.6 0.0025 18.3 0.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 EKX53349.1 - 0.0038 17.3 0.5 1.2 9.3 0.1 2.8 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 EKX53349.1 - 0.0049 17.1 0.4 0.1 12.9 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX53349.1 - 0.005 16.5 1.4 0.05 13.3 0.0 2.8 2 1 1 3 3 3 1 TPR repeat Fis1_TPR_C PF14853.6 EKX53349.1 - 0.3 11.2 11.8 0.38 10.9 0.1 3.9 3 1 1 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat Neprosin_AP PF14365.6 EKX53349.1 - 0.44 11.0 3.3 3.2 8.3 0.3 3.0 3 1 0 3 3 3 0 Neprosin activation peptide Acetyltransf_7 PF13508.7 EKX53350.1 - 3e-06 27.6 0.0 6.1e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EKX53350.1 - 5.7e-06 26.6 0.0 0.00028 21.1 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EKX53350.1 - 0.00016 21.6 0.0 0.0076 16.2 0.0 2.4 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EKX53350.1 - 0.0018 18.2 0.0 0.52 10.3 0.0 2.6 2 0 0 2 2 2 2 FR47-like protein SPRY PF00622.28 EKX53350.1 - 0.049 13.8 0.0 0.58 10.3 0.0 2.1 2 0 0 2 2 2 0 SPRY domain Acetyltransf_4 PF13420.7 EKX53350.1 - 0.06 13.5 0.0 1.6 8.9 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PfkB PF00294.24 EKX53351.1 - 5.4e-48 163.8 0.0 1.2e-47 162.7 0.0 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Topoisom_bac PF01131.20 EKX53352.1 - 2.8e-114 382.4 0.1 3.8e-114 381.9 0.1 1.2 1 0 0 1 1 1 1 DNA topoisomerase Toprim_C_rpt PF13368.6 EKX53352.1 - 1.1e-34 118.2 4.8 6.1e-12 45.4 0.0 6.0 5 1 1 6 6 6 4 Topoisomerase C-terminal repeat Toprim PF01751.22 EKX53352.1 - 7.7e-27 93.5 0.0 2.2e-26 92.1 0.0 1.8 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 EKX53352.1 - 0.00029 21.2 0.0 0.0012 19.3 0.0 2.1 2 0 0 2 2 2 1 Toprim domain Toprim_2 PF13155.6 EKX53352.1 - 0.0048 17.3 0.0 0.036 14.5 0.0 2.5 3 0 0 3 3 3 1 Toprim-like SNX17_FERM_C PF18116.1 EKX53352.1 - 0.17 11.9 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Sorting Nexin 17 FERM C-terminal domain HMG_box PF00505.19 EKX53353.1 - 9.7e-14 51.5 2.6 1.2e-13 51.2 2.6 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EKX53353.1 - 6.4e-11 42.7 2.7 7.7e-11 42.4 2.7 1.1 1 0 0 1 1 1 1 HMG-box domain PDZ_6 PF17820.1 EKX53354.1 - 1.1e-21 76.4 3.6 7.2e-10 38.6 0.3 2.5 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX53354.1 - 2.3e-21 75.9 6.6 4e-10 39.9 0.5 2.8 2 1 1 3 3 3 2 PDZ domain PDZ PF00595.24 EKX53354.1 - 1.9e-18 66.6 7.2 9.7e-09 35.5 1.0 2.5 2 0 0 2 2 2 2 PDZ domain Tricorn_PDZ PF14685.6 EKX53354.1 - 1.1e-10 41.4 1.4 0.00048 20.0 0.1 2.6 2 0 0 2 2 2 2 Tricorn protease PDZ domain Biotin_lipoyl_2 PF13533.6 EKX53354.1 - 0.44 10.4 4.1 15 5.5 0.0 3.0 4 0 0 4 4 4 0 Biotin-lipoyl like LysM PF01476.20 EKX53356.1 - 1.2e-06 28.5 0.0 0.0013 18.8 0.1 2.7 3 0 0 3 3 3 2 LysM domain Beta_helix PF13229.6 EKX53357.1 - 5.3e-49 166.1 29.3 4e-12 46.3 1.2 4.4 1 1 4 5 5 5 5 Right handed beta helix region NosD PF05048.13 EKX53357.1 - 1.5e-34 119.3 5.5 9e-11 41.5 0.2 4.9 1 1 4 5 5 5 5 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.7 EKX53357.1 - 0.0003 20.7 8.6 3.4 7.4 0.2 5.1 3 1 2 6 6 6 3 Pectate lyase superfamily protein DUF1565 PF07602.11 EKX53357.1 - 0.01 15.2 6.8 3.3 7.0 0.3 3.9 2 1 0 3 3 3 0 Protein of unknown function (DUF1565) ETM PF17577.2 EKX53357.1 - 0.86 10.2 5.9 0.19 12.3 1.1 2.4 2 1 1 3 3 3 0 ECORI-T site UCH PF00443.29 EKX53358.1 - 3.1e-21 76.1 0.0 4.6e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EKX53358.1 - 4e-09 36.5 0.0 7.9e-09 35.5 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EKX53358.1 - 3.8e-06 27.1 0.3 3.8e-06 27.1 0.3 2.3 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Zip PF02535.22 EKX53359.1 - 8.1e-45 153.5 19.1 9.4e-32 110.5 11.8 2.5 1 1 1 2 2 2 2 ZIP Zinc transporter SPC12 PF06645.13 EKX53359.1 - 8.3 6.6 8.3 2.1 8.5 1.5 2.9 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) EF-hand_8 PF13833.6 EKX53360.1 - 0.00011 22.0 0.4 0.00032 20.5 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair Ax_dynein_light PF10211.9 EKX53360.1 - 0.00012 22.1 8.5 0.00012 22.1 8.5 2.5 1 1 1 2 2 2 1 Axonemal dynein light chain EF-hand_1 PF00036.32 EKX53360.1 - 0.00018 20.8 0.1 0.00058 19.2 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 EKX53360.1 - 0.0019 17.6 0.2 0.0054 16.2 0.2 1.8 1 0 0 1 1 1 1 EF hand EF-hand_4 PF12763.7 EKX53360.1 - 0.004 17.1 2.5 0.018 15.0 0.0 3.3 4 0 0 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 EKX53360.1 - 0.012 16.1 0.2 0.012 16.1 0.2 2.7 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_6 PF13405.6 EKX53360.1 - 0.041 13.8 0.2 0.2 11.7 0.1 2.3 2 0 0 2 2 1 0 EF-hand domain XhlA PF10779.9 EKX53360.1 - 0.46 10.7 4.4 1.9 8.8 4.4 2.1 1 0 0 1 1 1 0 Haemolysin XhlA Rab_bind PF16704.5 EKX53360.1 - 0.47 10.5 5.8 1.7 8.7 5.8 2.0 1 0 0 1 1 1 0 Rab binding domain UCH PF00443.29 EKX53360.1 - 2.5 7.5 4.6 15 5.0 2.0 2.4 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Tropomyosin_1 PF12718.7 EKX53360.1 - 3.1 7.9 20.3 0.37 11.0 15.6 1.8 2 0 0 2 2 2 0 Tropomyosin like Beach PF02138.18 EKX53361.1 - 5.8e-107 357.2 0.0 6.6e-107 357.0 0.0 1.0 1 0 0 1 1 1 1 Beige/BEACH domain TIP120 PF08623.10 EKX53362.1 - 1.7e-42 145.1 0.8 1.7e-42 145.1 0.8 6.7 8 0 0 8 8 8 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 EKX53362.1 - 1.4e-19 70.2 15.4 1.4e-05 25.4 0.0 8.8 8 1 1 9 9 8 4 HEAT repeats HEAT PF02985.22 EKX53362.1 - 2.2e-16 58.5 23.9 0.014 15.6 0.2 12.3 13 0 0 13 13 12 3 HEAT repeat HEAT_EZ PF13513.6 EKX53362.1 - 1.9e-09 37.8 12.9 2.9 8.5 0.1 9.9 9 0 0 9 9 9 2 HEAT-like repeat Arm PF00514.23 EKX53362.1 - 3.9e-05 23.5 3.0 5.6 7.1 0.0 6.7 8 0 0 8 8 6 1 Armadillo/beta-catenin-like repeat RICTOR_N PF14664.6 EKX53362.1 - 0.00024 20.2 0.2 4 6.3 0.0 4.8 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, N-term Tti2 PF10521.9 EKX53362.1 - 0.00046 19.8 0.8 0.42 10.1 0.1 4.0 3 0 0 3 3 3 1 Tti2 family Vac14_Fab1_bd PF12755.7 EKX53362.1 - 0.00055 20.5 2.1 2.4 8.8 0.0 5.9 6 2 2 8 8 6 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EKX53362.1 - 0.0012 18.9 27.4 0.81 9.7 0.2 7.8 5 3 3 8 8 8 2 non-SMC mitotic condensation complex subunit 1 TAF6_C PF07571.13 EKX53362.1 - 0.0018 18.6 1.0 8.3 6.8 0.0 5.5 4 1 1 5 5 5 0 TAF6 C-terminal HEAT repeat domain MMS19_N PF14500.6 EKX53362.1 - 0.0019 17.9 15.4 0.14 11.7 0.2 6.0 4 3 2 6 6 6 2 Dos2-interacting transcription regulator of RNA-Pol-II Sec7_N PF12783.7 EKX53362.1 - 0.0033 17.4 8.2 0.86 9.5 0.1 5.6 5 1 1 6 6 6 1 Guanine nucleotide exchange factor in Golgi transport N-terminal RTP1_C1 PF10363.9 EKX53362.1 - 0.0048 17.1 18.9 0.39 10.9 0.0 7.4 8 1 1 9 9 8 2 Required for nuclear transport of RNA pol II C-terminus 1 MMS22L_C PF14911.6 EKX53362.1 - 0.01 14.9 3.1 0.046 12.8 0.0 3.1 3 0 0 3 3 3 0 S-phase genomic integrity recombination mediator, C-terminal DUF3361 PF11841.8 EKX53362.1 - 0.013 15.4 11.8 1.2 9.1 0.4 5.7 5 1 0 5 5 5 0 Domain of unknown function (DUF3361) MetOD1 PF18546.1 EKX53362.1 - 0.019 14.9 0.1 1.8 8.5 0.0 4.1 4 1 0 4 4 3 0 Metanogen output domain 1 UME PF08064.13 EKX53362.1 - 0.026 14.4 8.5 9.4 6.2 0.0 7.3 6 2 1 7 7 6 0 UME (NUC010) domain DUF3385 PF11865.8 EKX53362.1 - 0.12 12.3 17.6 0.66 9.9 0.0 7.4 7 2 1 8 8 8 0 Domain of unknown function (DUF3385) CbiG_C PF01890.16 EKX53362.1 - 0.32 11.6 3.6 0.74 10.4 0.1 2.9 3 0 0 3 3 2 0 Cobalamin synthesis G C-terminus ParcG PF10274.9 EKX53362.1 - 0.64 10.1 12.6 16 5.6 0.0 5.4 6 1 0 6 6 6 0 Parkin co-regulated protein API5 PF05918.11 EKX53362.1 - 1 8.1 13.1 0.49 9.2 1.1 4.8 6 0 0 6 6 6 0 Apoptosis inhibitory protein 5 (API5) PNPase PF03726.14 EKX53362.1 - 2.4 8.7 6.7 4.6 7.8 0.6 3.8 2 1 1 3 3 3 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain TFCD_C PF12612.8 EKX53362.1 - 3.3 7.5 7.4 1.2 9.0 0.0 4.0 5 1 0 5 5 5 0 Tubulin folding cofactor D C terminal GlutR_dimer PF00745.20 EKX53362.1 - 3.9 8.0 7.5 12 6.4 1.8 3.6 3 0 0 3 3 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain NPV_P10 PF05531.12 EKX53363.1 - 0.00015 22.2 3.8 0.00025 21.4 0.4 2.1 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein AIP3 PF03915.13 EKX53363.1 - 0.0033 16.6 1.7 0.0042 16.2 1.7 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 Laminin_II PF06009.12 EKX53363.1 - 0.004 17.2 4.7 0.0081 16.2 4.7 1.5 1 1 0 1 1 1 1 Laminin Domain II GAS PF13851.6 EKX53363.1 - 0.0042 16.4 1.8 0.05 12.9 0.2 2.0 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding MAD PF05557.13 EKX53363.1 - 0.0043 15.5 3.3 0.0049 15.3 3.3 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein Baculo_PEP_C PF04513.12 EKX53363.1 - 0.0081 16.2 1.7 0.009 16.1 0.3 1.6 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Lzipper-MIP1 PF14389.6 EKX53363.1 - 0.0089 16.3 0.4 0.015 15.6 0.4 1.3 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 TPR_MLP1_2 PF07926.12 EKX53363.1 - 0.012 15.7 3.7 0.017 15.2 0.5 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Nsp1_C PF05064.13 EKX53363.1 - 0.013 15.3 0.3 0.013 15.3 0.3 1.7 2 0 0 2 2 2 0 Nsp1-like C-terminal region CENP-F_leu_zip PF10473.9 EKX53363.1 - 0.016 15.2 0.3 0.016 15.2 0.3 1.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 EKX53363.1 - 0.017 14.7 0.6 0.017 14.7 0.6 1.9 1 1 1 2 2 2 0 Intermediate filament protein ATP-synt_D PF01813.17 EKX53363.1 - 0.021 14.7 1.1 0.11 12.3 0.1 1.9 1 1 1 2 2 2 0 ATP synthase subunit D DUF812 PF05667.11 EKX53363.1 - 0.027 13.4 3.7 0.032 13.1 3.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF1664 PF07889.12 EKX53363.1 - 0.035 14.1 1.8 0.48 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 EKX53363.1 - 0.038 14.0 0.4 0.038 14.0 0.4 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding BLOC1_2 PF10046.9 EKX53363.1 - 0.045 14.0 1.5 0.13 12.6 0.2 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF5082 PF16888.5 EKX53363.1 - 0.046 14.0 2.4 0.072 13.4 2.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Med9 PF07544.13 EKX53363.1 - 0.062 13.4 1.5 0.26 11.4 1.4 2.0 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Tmemb_cc2 PF10267.9 EKX53363.1 - 0.074 12.2 3.8 0.092 11.9 3.8 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein CLZ PF16526.5 EKX53363.1 - 0.13 12.6 2.5 0.17 12.3 0.3 2.0 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Sec2p PF06428.11 EKX53363.1 - 0.14 12.1 0.4 0.14 12.1 0.4 2.0 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p UPF0242 PF06785.11 EKX53363.1 - 0.18 11.9 6.2 1.5 8.9 6.2 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Uds1 PF15456.6 EKX53363.1 - 0.19 11.9 3.3 0.55 10.4 3.3 1.7 1 1 0 1 1 1 0 Up-regulated During Septation Fib_alpha PF08702.10 EKX53363.1 - 0.22 11.7 2.9 0.55 10.4 2.9 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 EKX53363.1 - 0.23 11.7 2.4 0.3 11.3 0.2 2.0 2 0 0 2 2 2 0 Haemolysin XhlA DivIC PF04977.15 EKX53363.1 - 0.26 11.1 5.4 0.14 12.0 0.6 2.1 2 0 0 2 2 2 0 Septum formation initiator DUF4407 PF14362.6 EKX53363.1 - 0.32 10.3 1.9 0.4 10.0 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 EKX53363.1 - 0.33 11.2 3.5 0.18 12.1 0.6 1.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Syntaxin-6_N PF09177.11 EKX53363.1 - 0.33 11.5 4.5 0.61 10.7 2.9 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Spc7 PF08317.11 EKX53363.1 - 0.49 9.2 4.6 0.79 8.5 4.6 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein Cnn_1N PF07989.11 EKX53363.1 - 0.52 10.5 4.1 3.3 7.9 0.3 2.3 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 FlxA PF14282.6 EKX53363.1 - 2.2 8.3 7.6 0.39 10.7 2.3 2.2 1 1 0 2 2 2 0 FlxA-like protein DUF16 PF01519.16 EKX53363.1 - 4.5 7.8 7.8 2.5e+02 2.2 7.8 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 PLAC8 PF04749.17 EKX53365.1 - 1.7e-10 41.7 0.2 3.2e-10 40.9 0.2 1.5 1 0 0 1 1 1 1 PLAC8 family Fis1_TPR_C PF14853.6 EKX53366.1 - 0.046 13.8 0.0 0.086 12.9 0.0 1.4 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat GGN PF15685.5 EKX53366.1 - 1 8.4 2.6 16 4.4 0.1 2.0 2 0 0 2 2 2 0 Gametogenetin DNA_ligase_A_N PF04675.14 EKX53367.1 - 4.8e-42 144.2 0.0 8.6e-42 143.4 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 EKX53367.1 - 4.9e-28 98.2 0.0 2.4e-17 63.3 0.0 2.4 1 1 1 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 EKX53367.1 - 4e-21 75.5 0.0 2.1e-20 73.1 0.0 2.4 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EKX53367.1 - 0.0021 18.4 0.1 0.0044 17.3 0.1 1.6 1 0 0 1 1 1 1 RNA ligase mRNA_cap_enzyme PF01331.19 EKX53367.1 - 0.058 13.2 0.2 0.45 10.3 0.0 2.2 1 1 1 2 2 2 0 mRNA capping enzyme, catalytic domain Biotin_lipoyl PF00364.22 EKX53368.1 - 0.17 11.7 0.0 0.78 9.6 0.0 2.0 2 0 0 2 2 2 0 Biotin-requiring enzyme Pkinase PF00069.25 EKX53369.1 - 5.3e-64 216.1 0.0 1.1e-63 215.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX53369.1 - 1.8e-35 122.5 0.0 2.5e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX53369.1 - 1.7e-05 24.3 0.0 2.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EKX53369.1 - 0.00013 21.1 0.0 0.00023 20.2 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EKX53369.1 - 0.0026 16.6 0.0 0.0061 15.4 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX53369.1 - 0.025 14.5 0.1 0.044 13.7 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EKX53369.1 - 0.046 13.1 0.0 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family CAF1 PF04857.20 EKX53370.1 - 1.9e-46 158.7 1.5 6.8e-40 137.2 0.6 2.2 1 1 1 2 2 2 2 CAF1 family ribonuclease R3H PF01424.22 EKX53370.1 - 0.00044 20.2 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 R3H domain IFT20 PF14931.6 EKX53370.1 - 0.18 12.0 3.2 2.1 8.5 0.7 2.5 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 zf-RING_2 PF13639.6 EKX53371.1 - 1.3e-08 35.0 0.5 1.3e-08 35.0 0.5 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX53371.1 - 2.7e-07 30.3 0.3 2.7e-07 30.3 0.3 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX53371.1 - 9.6e-05 22.6 3.2 0.00048 20.4 3.2 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EKX53371.1 - 0.00032 20.6 1.3 0.00087 19.2 0.0 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EKX53371.1 - 0.00064 19.7 0.0 0.002 18.1 0.0 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EKX53371.1 - 0.0013 18.6 0.1 0.0013 18.6 0.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EKX53371.1 - 0.0031 17.2 0.0 0.0089 15.8 0.0 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EKX53371.1 - 0.0042 16.9 0.1 0.0042 16.9 0.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EKX53371.1 - 0.1 12.7 0.4 0.1 12.7 0.4 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 Fer2_BFD PF04324.15 EKX53371.1 - 0.15 12.4 0.9 0.82 10.1 0.2 2.4 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain Prok-RING_4 PF14447.6 EKX53371.1 - 0.23 11.3 0.0 0.23 11.3 0.0 2.7 3 0 0 3 3 2 0 Prokaryotic RING finger family 4 RecR PF02132.15 EKX53371.1 - 3.2 7.4 9.8 3.1 7.4 0.2 3.5 3 0 0 3 3 3 0 RecR protein zf-P11 PF03854.14 EKX53371.1 - 9.8 5.9 9.1 0.21 11.3 0.3 2.7 4 0 0 4 4 4 0 P-11 zinc finger SPX PF03105.19 EKX53372.1 - 5e-22 79.3 7.8 1.2e-09 38.6 0.1 3.0 1 1 2 3 3 3 3 SPX domain eIF3_subunit PF08597.10 EKX53373.1 - 0.0026 17.7 9.9 0.0026 17.7 9.9 2.2 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit PNISR PF15996.5 EKX53373.1 - 0.0071 16.6 7.3 0.0071 16.6 7.3 2.7 2 1 0 2 2 2 1 Arginine/serine-rich protein PNISR NAM-associated PF14303.6 EKX53373.1 - 0.0097 16.6 17.6 0.0097 16.6 17.6 2.4 2 1 0 2 2 2 1 No apical meristem-associated C-terminal domain RE_R_Pab1 PF09522.10 EKX53373.1 - 0.053 13.6 0.8 0.43 10.7 0.1 2.3 1 1 1 2 2 2 0 R.Pab1 restriction endonuclease IQ PF00612.27 EKX53373.1 - 0.081 12.8 1.5 0.15 11.9 0.1 2.3 2 0 0 2 2 2 0 IQ calmodulin-binding motif SRP-alpha_N PF04086.13 EKX53373.1 - 0.21 11.5 22.1 0.066 13.1 18.5 1.8 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal SOBP PF15279.6 EKX53373.1 - 0.24 12.0 8.3 0.34 11.5 8.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein CDC45 PF02724.14 EKX53373.1 - 0.34 9.1 15.6 0.52 8.5 15.6 1.3 1 0 0 1 1 1 0 CDC45-like protein U79_P34 PF03064.16 EKX53373.1 - 0.97 8.7 18.0 1.9 7.8 18.0 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Connexin PF00029.19 EKX53373.1 - 1.5 8.5 6.6 3.2 7.5 6.6 1.7 1 0 0 1 1 1 0 Connexin RNA_polI_A34 PF08208.11 EKX53373.1 - 4.4 7.3 30.3 0.11 12.6 23.7 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.12 EKX53373.1 - 5.3 6.8 14.7 0.94 9.3 10.8 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF4614 PF15391.6 EKX53373.1 - 5.8 6.9 25.6 0.056 13.4 2.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4614) DUF4228 PF14009.6 EKX53373.1 - 8.1 6.8 15.9 17 5.7 15.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Neur_chan_memb PF02932.16 EKX53373.1 - 8.6 6.3 10.6 28 4.6 7.8 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region RCC1_2 PF13540.6 EKX53374.1 - 6.5e-20 70.4 19.4 1.6e-05 24.6 2.0 5.6 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat DUF563 PF04577.14 EKX53374.1 - 2.1e-15 57.5 0.0 3.9e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) RCC1 PF00415.18 EKX53374.1 - 0.0073 16.9 4.5 4.1 8.1 0.0 5.1 4 1 1 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat AAA_6 PF12774.7 EKX53375.1 - 5.7e-157 521.8 0.0 2.9e-156 519.5 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EKX53375.1 - 3.5e-125 418.2 14.4 3.5e-125 418.2 14.4 4.2 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EKX53375.1 - 4.8e-109 363.7 0.0 1.4e-108 362.2 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EKX53375.1 - 4.3e-103 344.7 1.3 3e-98 328.8 0.0 3.7 3 0 0 3 3 3 2 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EKX53375.1 - 1.9e-96 321.5 0.2 1.9e-95 318.2 0.1 3.0 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 EKX53375.1 - 1.1e-63 214.1 0.8 2.1e-60 203.3 0.0 3.8 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EKX53375.1 - 1.1e-57 194.5 0.2 2.8e-57 193.1 0.2 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 EKX53375.1 - 1.1e-51 175.9 18.1 2.8e-51 174.6 18.1 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EKX53375.1 - 3.8e-47 159.3 0.1 1.3e-42 144.7 0.0 3.5 3 0 0 3 3 2 2 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EKX53375.1 - 2.8e-23 82.4 0.1 1.6e-22 80.0 0.1 2.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EKX53375.1 - 1.2e-18 67.1 0.4 1.3e-17 63.8 0.1 3.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 EKX53375.1 - 1.3e-15 57.6 0.0 3.2e-05 24.0 0.0 6.8 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EKX53375.1 - 1.3e-05 25.7 10.4 0.042 14.2 0.0 6.3 7 1 1 8 8 6 1 AAA ATPase domain AAA PF00004.29 EKX53375.1 - 1.5e-05 25.5 2.6 0.34 11.3 0.0 5.2 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EKX53375.1 - 7.5e-05 23.3 0.1 1 9.9 0.0 4.8 4 0 0 4 4 3 1 AAA domain AAA_22 PF13401.6 EKX53375.1 - 0.0004 20.7 0.6 2.5 8.4 0.0 5.1 5 0 0 5 5 4 1 AAA domain Roc PF08477.13 EKX53375.1 - 0.023 14.9 0.5 2 8.7 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 EKX53375.1 - 0.023 15.1 0.5 24 5.4 0.0 4.4 4 0 0 4 4 3 0 RNA helicase MIT PF04212.18 EKX53375.1 - 0.086 12.9 1.2 0.74 9.9 1.2 2.8 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain AAA_33 PF13671.6 EKX53375.1 - 0.16 12.2 0.4 29 4.8 0.0 3.9 3 0 0 3 3 3 0 AAA domain ATPase PF06745.13 EKX53375.1 - 1.8 7.9 6.9 1.1 8.5 0.1 3.6 4 0 0 4 4 4 0 KaiC Mg_chelatase PF01078.21 EKX53375.1 - 5 6.5 8.8 0.25 10.7 0.0 3.1 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI TPK_catalytic PF04263.16 EKX53376.1 - 0.027 14.5 0.8 0.078 13.0 0.2 2.1 2 0 0 2 2 2 0 Thiamin pyrophosphokinase, catalytic domain DUF1003 PF06210.11 EKX53376.1 - 0.51 10.5 0.0 0.51 10.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1003) DUF1542 PF07564.11 EKX53376.1 - 8.9 6.5 9.8 9.5 6.4 3.0 3.3 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) DUF1289 PF06945.13 EKX53377.1 - 0.051 13.4 0.1 0.1 12.4 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) DUF765 PF05570.11 EKX53377.1 - 0.12 12.6 1.4 0.2 11.9 1.4 1.4 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF765) EIF_2_alpha PF07541.12 EKX53378.1 - 5.6e-35 119.9 0.0 1.2e-34 118.9 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EKX53378.1 - 1.3e-09 38.3 2.4 2.3e-09 37.5 2.4 1.4 1 0 0 1 1 1 1 S1 RNA binding domain UTP25 PF06862.12 EKX53379.1 - 5.4e-129 431.0 1.1 2.3e-126 422.4 1.1 3.1 1 1 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 SURF4 PF02077.15 EKX53380.1 - 0.096 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 SURF4 family Muted PF14942.6 EKX53381.1 - 0.034 14.5 0.9 0.12 12.7 0.9 2.0 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein E1-E2_ATPase PF00122.20 EKX53381.1 - 0.085 12.4 2.8 0.1 12.1 0.3 2.0 1 1 1 2 2 2 0 E1-E2 ATPase Fib_alpha PF08702.10 EKX53381.1 - 0.34 11.1 2.6 1.1 9.4 2.6 1.9 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 EKX53381.1 - 1 9.9 8.2 0.94 10.0 4.7 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DAO PF01266.24 EKX53383.1 - 3.3e-45 155.2 0.0 5.4e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 EKX53383.1 - 1.4e-35 121.9 0.1 2.8e-35 120.9 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 EKX53383.1 - 4.7e-09 35.8 2.8 5.1e-08 32.4 2.8 2.2 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EKX53383.1 - 4.6e-07 29.5 0.1 7.3e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 EKX53383.1 - 0.00018 20.7 1.1 0.048 12.7 0.2 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EKX53383.1 - 0.00037 19.8 0.1 0.0036 16.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EKX53383.1 - 0.00053 19.3 0.3 0.68 9.1 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EKX53383.1 - 0.0041 17.3 0.1 0.027 14.7 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EKX53383.1 - 0.014 14.6 0.1 0.49 9.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EKX53383.1 - 0.041 12.6 0.4 0.061 12.0 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 EKX53383.1 - 0.044 13.0 0.1 0.093 12.0 0.1 1.5 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.18 EKX53383.1 - 0.06 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 EKX53383.1 - 0.14 12.7 0.6 0.5 11.0 0.6 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_34 PF11312.8 EKX53383.1 - 0.16 11.2 0.1 0.4 9.9 0.0 1.6 2 0 0 2 2 2 0 Putative SAM-dependent methyltransferase Activator-TraM PF11657.8 EKX53384.1 - 0.38 10.6 2.6 1 9.2 2.6 1.7 1 0 0 1 1 1 0 Transcriptional activator TraM Sigma70_r3 PF04539.16 EKX53385.1 - 0.049 13.7 0.3 0.091 12.9 0.3 1.4 1 0 0 1 1 1 0 Sigma-70 region 3 SAM_1 PF00536.30 EKX53385.1 - 0.064 13.7 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Ank_5 PF13857.6 EKX53386.1 - 1.5e-13 50.7 0.2 2.8e-13 49.8 0.2 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX53386.1 - 2.8e-11 43.8 0.1 9.5e-09 35.7 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EKX53386.1 - 6.9e-11 42.1 0.3 6.2e-08 32.7 0.4 3.4 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 EKX53386.1 - 4.8e-10 39.8 0.1 8.7e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX53386.1 - 4.7e-08 32.7 0.1 2.8e-05 24.1 0.1 4.0 5 0 0 5 5 5 1 Ankyrin repeat Ubie_methyltran PF01209.18 EKX53389.1 - 6e-47 159.9 0.0 6.8e-47 159.8 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EKX53389.1 - 1.8e-17 63.8 0.1 3.5e-17 62.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX53389.1 - 9.5e-16 57.9 0.0 1.1e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX53389.1 - 4.8e-15 56.0 0.0 1.1e-14 54.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX53389.1 - 1.9e-12 47.8 0.1 3e-12 47.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX53389.1 - 8.2e-11 42.0 0.0 1.1e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EKX53389.1 - 1.1e-09 38.4 0.0 1.5e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_3 PF01596.17 EKX53389.1 - 0.0028 16.9 0.1 0.004 16.3 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase MetW PF07021.12 EKX53389.1 - 0.0071 16.0 0.1 0.15 11.6 0.1 2.2 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.20 EKX53389.1 - 0.0093 15.3 0.0 0.017 14.4 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase GCD14 PF08704.10 EKX53389.1 - 0.062 13.0 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Mannosyl_trans3 PF11051.8 EKX53390.1 - 1.8e-31 109.6 0.0 6.3e-24 84.8 0.0 2.0 1 1 1 2 2 2 2 Mannosyltransferase putative Kinesin PF00225.23 EKX53391.1 - 5.1e-11 42.1 0.1 5.1e-11 42.1 0.1 4.1 3 1 0 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 EKX53391.1 - 2.8e-06 27.3 0.1 2.8e-06 27.3 0.1 2.7 2 1 0 2 2 2 1 Microtubule binding FPP PF05911.11 EKX53391.1 - 0.0018 16.6 52.6 0.0018 16.6 52.6 3.9 2 1 3 5 5 5 2 Filament-like plant protein, long coiled-coil Amidohydro_3 PF07969.11 EKX53392.1 - 1.4e-12 47.8 0.3 3.3e-06 26.8 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 EKX53392.1 - 6.6e-12 45.4 0.0 2.5e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family WD40 PF00400.32 EKX53393.1 - 7e-16 58.3 3.1 0.018 15.9 0.0 5.9 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX53393.1 - 5.9e-08 32.9 0.2 2.8 8.3 0.0 6.0 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EKX53393.1 - 0.1 11.9 0.0 5.1 6.3 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain Kelch_3 PF13415.6 EKX53393.1 - 0.11 12.8 0.1 0.33 11.3 0.1 1.8 1 0 0 1 1 1 0 Galactose oxidase, central domain Lebercilin PF15619.6 EKX53394.1 - 0.024 14.3 16.5 0.028 14.1 16.5 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease 5_nucleotid PF05761.14 EKX53394.1 - 0.076 11.9 6.9 0.09 11.7 6.9 1.1 1 0 0 1 1 1 0 5' nucleotidase family Spc7 PF08317.11 EKX53394.1 - 0.086 11.7 17.4 0.086 11.7 17.4 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein SWI-SNF_Ssr4 PF08549.10 EKX53394.1 - 0.13 10.8 10.2 0.15 10.7 10.2 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DUF1664 PF07889.12 EKX53394.1 - 0.2 11.7 6.3 0.41 10.7 6.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) GAS PF13851.6 EKX53394.1 - 0.26 10.6 19.2 0.29 10.4 19.2 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1690 PF07956.11 EKX53394.1 - 0.38 11.2 12.5 0.49 10.8 12.5 1.1 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) YjcZ PF13990.6 EKX53394.1 - 0.52 9.6 6.0 0.58 9.5 6.0 1.1 1 0 0 1 1 1 0 YjcZ-like protein Prefoldin_2 PF01920.20 EKX53394.1 - 0.53 10.3 17.7 0.039 13.9 6.0 2.1 1 1 1 2 2 2 0 Prefoldin subunit DUF4407 PF14362.6 EKX53394.1 - 0.87 8.9 8.4 1.4 8.2 8.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DLP_helical PF18709.1 EKX53394.1 - 1.1 8.4 12.5 1.6 7.9 5.2 2.0 1 1 1 2 2 2 0 Dynamin-like helical domain DUF3810 PF12725.7 EKX53394.1 - 1.2 8.4 5.4 0.56 9.5 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) XhlA PF10779.9 EKX53394.1 - 2 8.7 6.4 0.67 10.2 0.4 2.4 2 1 1 3 3 3 0 Haemolysin XhlA Nup88 PF10168.9 EKX53394.1 - 2.5 5.8 12.3 2.8 5.6 12.3 1.0 1 0 0 1 1 1 0 Nuclear pore component Exonuc_VII_L PF02601.15 EKX53394.1 - 3.3 7.2 11.1 3.5 7.1 11.1 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.14 EKX53394.1 - 3.8 7.9 20.3 0.98 9.8 4.4 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) FapA PF03961.13 EKX53394.1 - 3.9 6.0 12.9 4.5 5.8 12.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Atg14 PF10186.9 EKX53394.1 - 7.1 5.6 13.4 8.4 5.4 13.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LRR_6 PF13516.6 EKX53395.1 - 1.3e-17 62.3 2.3 0.0079 16.2 0.0 6.1 6 0 0 6 6 6 4 Leucine Rich repeat LRR_8 PF13855.6 EKX53395.1 - 0.017 14.8 7.0 6.5 6.6 0.5 4.6 1 1 1 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 EKX53395.1 - 0.05 14.2 1.2 58 4.8 0.0 5.1 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.7 EKX53395.1 - 0.47 11.0 14.8 0.68 10.4 0.3 5.1 3 1 4 7 7 7 0 Leucine Rich repeats (2 copies) FapA PF03961.13 EKX53395.1 - 0.52 8.9 5.2 0.97 8.0 5.2 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A PI3K_P85_iSH2 PF16454.5 EKX53395.1 - 2.9 7.5 13.0 2 8.0 9.5 2.5 2 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Ank_2 PF12796.7 EKX53396.1 - 1.8e-17 63.7 4.9 2.9e-07 31.0 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX53396.1 - 8.8e-14 51.7 0.3 1e-06 29.1 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX53396.1 - 4.4e-13 49.2 0.2 0.0011 19.3 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EKX53396.1 - 3.4e-07 30.4 2.8 0.00094 19.5 0.1 4.5 4 1 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 EKX53396.1 - 2e-06 27.7 1.3 15 6.5 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Drf_FH3 PF06367.16 EKX53397.1 - 0.37 10.4 2.1 3.8 7.1 0.1 2.7 3 0 0 3 3 3 0 Diaphanous FH3 Domain DUF1794 PF08768.11 EKX53398.1 - 1.3e-29 103.0 0.0 1.5e-29 102.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) Myb_DNA-binding PF00249.31 EKX53399.1 - 5.3e-32 109.8 14.9 4.4e-11 42.8 0.3 5.0 4 0 0 4 4 4 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX53399.1 - 2.8e-25 88.4 18.7 1.2e-13 51.1 0.8 5.2 6 0 0 6 6 6 4 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EKX53399.1 - 7.2e-07 29.5 19.1 0.00017 21.9 2.3 6.5 4 1 2 6 6 6 1 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 EKX53399.1 - 0.00022 21.2 0.0 0.7 10.0 0.0 3.5 2 1 1 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 EKX53399.1 - 0.023 14.7 7.4 1.6 8.8 0.0 4.0 4 1 2 6 6 6 0 SLIDE DUF2789 PF10982.8 EKX53399.1 - 2 8.6 6.6 8.5 6.6 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2789) DUF4706 PF15797.5 EKX53399.1 - 3.9 8.1 9.0 0.87 10.1 0.2 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4706) DEAD PF00270.29 EKX53400.1 - 1e-21 77.5 0.0 2.4e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX53400.1 - 1.6e-17 63.9 0.0 9.3e-16 58.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EKX53400.1 - 1.4e-09 38.5 1.1 1.4e-09 38.5 1.1 2.0 2 0 0 2 2 2 1 RecQ zinc-binding RQC PF09382.10 EKX53400.1 - 9.3e-06 25.4 0.2 0.065 13.0 0.0 3.1 3 0 0 3 3 3 2 RQC domain AAA_22 PF13401.6 EKX53400.1 - 0.046 14.0 0.1 0.19 12.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain zf-RING_2 PF13639.6 EKX53401.1 - 5.2e-17 61.9 21.1 7e-10 39.1 4.1 2.4 2 0 0 2 2 2 2 Ring finger domain zf-RING_11 PF17123.5 EKX53401.1 - 4e-16 58.4 14.7 6.5e-08 32.2 3.7 2.6 2 0 0 2 2 2 2 RING-like zinc finger zf-RING_UBOX PF13445.6 EKX53401.1 - 1.3e-11 44.3 15.1 1.1e-06 28.5 3.4 3.0 2 1 1 3 3 3 2 RING-type zinc-finger zf-RING_5 PF14634.6 EKX53401.1 - 6.1e-10 38.9 23.5 1.3e-05 25.0 7.1 2.4 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.25 EKX53401.1 - 1.9e-08 34.0 17.5 1.1e-05 25.2 3.1 2.6 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX53401.1 - 1.5e-07 31.6 22.3 0.00021 21.5 6.3 3.6 2 2 0 2 2 2 2 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EKX53401.1 - 1.7e-07 31.0 22.2 1.1e-06 28.4 3.5 2.8 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EKX53401.1 - 1.1e-06 28.6 13.0 0.0024 17.9 1.9 2.9 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EKX53401.1 - 1.3e-06 28.1 19.2 4.5e-05 23.2 3.2 2.6 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EKX53401.1 - 1.9e-06 27.6 21.3 0.00069 19.4 6.2 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EKX53401.1 - 0.0004 19.9 18.5 0.0042 16.7 5.2 2.9 2 0 0 2 2 2 2 Zinc-ribbon, C4HC2 type IQ PF00612.27 EKX53401.1 - 0.0012 18.4 0.2 0.0031 17.2 0.2 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif Octopine_DH PF02317.17 EKX53401.1 - 0.033 14.3 0.0 0.81 9.8 0.0 2.1 2 0 0 2 2 2 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain zf-UDP PF14569.6 EKX53401.1 - 0.29 11.3 14.3 1.1 9.4 3.3 2.6 2 0 0 2 2 2 0 Zinc-binding RING-finger PHD PF00628.29 EKX53401.1 - 0.41 10.6 18.7 0.21 11.5 3.6 2.7 2 0 0 2 2 2 0 PHD-finger Zf_RING PF16744.5 EKX53401.1 - 2 8.6 15.9 0.96 9.6 4.3 2.8 2 0 0 2 2 2 0 KIAA1045 RING finger zf-Nse PF11789.8 EKX53401.1 - 5.1 7.0 9.5 4.8 7.1 1.6 2.5 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 EKX53401.1 - 7.2 6.9 21.5 0.26 11.5 3.9 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EKX53401.1 - 8.9 6.2 20.1 6.5 6.6 3.0 3.3 2 2 2 4 4 4 0 RING/Ubox like zinc-binding domain NDUFA12 PF05071.16 EKX53402.1 - 9e-11 42.5 1.0 1.6e-10 41.7 1.0 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Glyco_transf_8 PF01501.20 EKX53403.1 - 7.6e-12 45.3 3.8 3.2e-11 43.3 3.8 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Filamin PF00630.19 EKX53403.1 - 1.7e-06 28.8 0.0 4.2e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Filamin/ABP280 repeat Nucleotid_trans PF03407.16 EKX53403.1 - 0.0005 20.1 0.1 0.00086 19.3 0.1 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase zf-trcl PF13451.6 EKX53404.1 - 1.3e-07 31.4 3.3 2e-07 30.8 0.4 2.4 2 0 0 2 2 2 1 Probable zinc-ribbon domain Toprim PF01751.22 EKX53406.1 - 2.8e-24 85.3 0.0 3.2e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 EKX53406.1 - 0.06 13.8 0.0 0.12 12.8 0.0 1.6 2 0 0 2 2 2 0 Toprim domain Toprim_2 PF13155.6 EKX53406.1 - 0.067 13.6 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Toprim-like Shikimate_dh_N PF08501.11 EKX53406.1 - 0.08 13.2 0.0 0.24 11.7 0.0 1.8 2 0 0 2 2 2 0 Shikimate dehydrogenase substrate binding domain Baculo_PEP_C PF04513.12 EKX53407.1 - 0.059 13.4 1.4 0.12 12.4 1.4 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NapD PF03927.13 EKX53407.1 - 0.077 13.1 3.0 0.14 12.2 0.4 2.8 1 1 0 2 2 2 0 NapD protein FdhE PF04216.12 EKX53407.1 - 5.8 6.7 13.7 0.99 9.2 9.2 1.8 1 1 0 1 1 1 0 Protein involved in formate dehydrogenase formation CdvA PF18822.1 EKX53408.1 - 0.1 12.4 0.3 13 5.6 0.0 2.2 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Glyco_transf_29 PF00777.18 EKX53409.1 - 4.1e-33 114.9 0.0 2.5e-32 112.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 29 (sialyltransferase) UvrD-helicase PF00580.21 EKX53410.1 - 9.2e-25 87.8 0.2 1.2e-24 87.4 0.2 1.2 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 EKX53410.1 - 9.1e-17 61.7 0.3 2.1e-16 60.6 0.3 1.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EKX53410.1 - 0.00023 20.9 0.3 0.00035 20.4 0.3 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EKX53410.1 - 0.0011 18.8 0.2 0.0022 17.8 0.1 1.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 EKX53410.1 - 0.12 12.4 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CRISPR_Cas2 PF09827.9 EKX53410.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 CRISPR associated protein Cas2 Radical_SAM_C PF16199.5 EKX53410.1 - 0.17 12.0 0.0 0.35 10.9 0.0 1.6 1 1 0 1 1 1 0 Radical_SAM C-terminal domain DSPn PF14671.6 EKX53411.1 - 1e-34 120.0 0.1 1.1e-33 116.7 0.0 2.4 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EKX53411.1 - 4.9e-16 58.8 0.0 1.3e-15 57.4 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EKX53411.1 - 8.2e-06 26.0 0.0 1.2e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 EKX53411.1 - 1.7e-05 24.5 0.0 2.3e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EKX53411.1 - 0.0037 17.3 0.0 0.0053 16.7 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EKX53411.1 - 0.0067 16.0 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family N6_Mtase PF02384.16 EKX53412.1 - 0.027 13.7 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 N-6 DNA Methylase Cons_hypoth95 PF03602.15 EKX53412.1 - 0.048 13.3 0.0 0.06 13.0 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF2997 PF11211.8 EKX53413.1 - 9.7e-21 73.3 0.6 1.6e-20 72.6 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2997) HVSL PF09749.9 EKX53414.1 - 3.2e-39 134.8 0.6 3.6e-39 134.6 0.6 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein LigT_PEase PF02834.16 EKX53414.1 - 0.011 15.9 0.1 0.025 14.8 0.1 1.7 2 0 0 2 2 2 0 LigT like Phosphoesterase GpcrRhopsn4 PF10192.9 EKX53415.1 - 1.1e-34 120.0 22.9 1.4e-34 119.7 22.9 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 EKX53415.1 - 0.0026 17.1 18.4 0.0044 16.3 18.4 1.3 1 0 0 1 1 1 1 Lung seven transmembrane receptor DNA_pol_E_B PF04042.16 EKX53416.1 - 1.7e-24 86.3 0.0 5.4e-14 52.0 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 EKX53416.1 - 7.7e-07 29.3 0.2 7.7e-07 29.3 0.2 2.3 2 0 0 2 2 2 1 DNA polymerase alpha subunit B N-terminal Glycos_transf_2 PF00535.26 EKX53417.1 - 1.3e-06 28.3 0.0 0.75 9.6 0.0 3.6 3 0 0 3 3 3 3 Glycosyl transferase family 2 Thioredoxin PF00085.20 EKX53418.1 - 1.4e-06 28.2 0.1 1.7e-06 28.0 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 EKX53418.1 - 0.02 13.8 0.0 0.024 13.6 0.0 1.0 1 0 0 1 1 1 0 Phosducin PDZ PF00595.24 EKX53419.1 - 3.8e-09 36.8 0.1 8e-09 35.7 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX53419.1 - 7.8e-09 35.3 0.0 1.6e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX53419.1 - 2.1e-05 24.8 0.2 4.2e-05 23.8 0.2 1.5 1 0 0 1 1 1 1 PDZ domain DUF4461 PF14688.6 EKX53419.1 - 0.0024 17.7 0.4 0.0024 17.7 0.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4461) DpnD-PcfM PF14207.6 EKX53419.1 - 0.13 12.2 0.7 0.8 9.6 0.2 2.2 2 0 0 2 2 2 0 DpnD/PcfM-like protein Golgin_A5 PF09787.9 EKX53419.1 - 0.34 10.3 23.9 0.17 11.3 9.5 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 LMBR1 PF04791.16 EKX53419.1 - 5.6 5.8 6.6 8.5 5.1 6.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein GP17 PF17420.2 EKX53420.1 - 0.1 12.8 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Superinfection exclusion gene product 17 FGF PF00167.18 EKX53420.1 - 0.12 12.5 0.8 0.64 10.1 0.1 2.2 2 0 0 2 2 2 0 Fibroblast growth factor WD40 PF00400.32 EKX53422.1 - 1.7e-15 57.1 7.5 1.5e-06 28.8 0.4 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 EKX53422.1 - 2.4e-10 40.5 0.0 8.1e-10 38.8 0.0 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex TFIIF_alpha PF05793.12 EKX53422.1 - 0.57 8.7 25.4 0.86 8.1 25.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Presenilin PF01080.17 EKX53422.1 - 3.8 6.2 6.3 5.6 5.6 6.3 1.2 1 0 0 1 1 1 0 Presenilin C2 PF00168.30 EKX53423.1 - 1e-23 83.6 0.0 1.1e-23 83.5 0.0 1.0 1 0 0 1 1 1 1 C2 domain Syja_N PF02383.18 EKX53424.1 - 5.5e-39 134.3 0.0 9e-39 133.7 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain LysM PF01476.20 EKX53425.1 - 1.4e-08 34.7 0.0 9.9e-07 28.7 0.0 2.6 2 0 0 2 2 2 2 LysM domain Glyco_trans_1_2 PF13524.6 EKX53426.1 - 0.00027 21.3 0.0 0.00063 20.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 TBCA PF02970.16 EKX53427.1 - 0.15 12.4 1.8 0.44 10.9 1.4 2.0 1 1 0 1 1 1 0 Tubulin binding cofactor A Cwf_Cwc_15 PF04889.12 EKX53428.1 - 0.00044 20.1 16.7 0.00044 20.1 16.7 2.5 2 1 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.13 EKX53428.1 - 0.00068 19.6 6.1 0.00068 19.6 6.1 2.9 2 1 0 2 2 2 1 Sigma-70, non-essential region Zf_RING PF16744.5 EKX53428.1 - 0.021 14.9 5.9 0.13 12.4 1.6 2.7 2 0 0 2 2 2 0 KIAA1045 RING finger NOA36 PF06524.12 EKX53428.1 - 0.024 14.0 22.1 0.053 12.8 22.1 1.5 1 0 0 1 1 1 0 NOA36 protein zf-C5HC2 PF02928.16 EKX53428.1 - 0.063 13.7 0.1 0.063 13.7 0.1 2.7 3 0 0 3 3 3 0 C5HC2 zinc finger Zn_ribbon_17 PF17120.5 EKX53428.1 - 0.71 9.5 6.1 2 8.1 6.1 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type C1_1 PF00130.22 EKX53428.1 - 0.95 9.4 7.6 2.9 7.9 7.6 1.8 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PriX PF18689.1 EKX53428.1 - 1.8 9.0 4.6 5.2 7.5 0.1 3.4 3 0 0 3 3 3 0 Primase X DUF913 PF06025.12 EKX53428.1 - 9.2 5.1 10.2 0.3 10.0 2.7 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Death PF00531.22 EKX53429.1 - 0.034 14.3 0.1 0.13 12.4 0.1 2.2 1 0 0 1 1 1 0 Death domain H-kinase_dim PF02895.14 EKX53429.1 - 1.8 9.0 4.4 2.5 8.6 0.9 3.1 3 0 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain ATC_hydrolase PF14196.6 EKX53430.1 - 0.00064 20.5 1.3 0.0011 19.8 0.4 1.8 2 1 0 2 2 2 1 L-2-amino-thiazoline-4-carboxylic acid hydrolase POC1 PF10450.9 EKX53430.1 - 0.082 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 POC1 chaperone mTERF PF02536.14 EKX53432.1 - 2.5e-27 95.6 0.2 3.3e-27 95.2 0.2 1.1 1 0 0 1 1 1 1 mTERF DUF1947 PF09183.10 EKX53432.1 - 0.0016 18.7 0.7 1.6 9.1 0.0 3.1 1 1 2 3 3 3 2 Domain of unknown function (DUF1947) DUF1474 PF07342.11 EKX53432.1 - 0.018 15.5 0.0 0.44 11.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1474) Pkinase PF00069.25 EKX53433.1 - 1.4e-06 27.9 0.0 2.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EKX53433.1 - 0.013 15.4 1.4 0.036 14.0 0.4 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EKX53433.1 - 0.025 14.2 0.0 0.13 11.8 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 EKX53433.1 - 0.06 12.6 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase Glyco_transf_15 PF01793.16 EKX53434.1 - 2.9e-33 115.5 3.3 1.3e-30 106.8 2.1 2.8 1 1 1 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase TPR_11 PF13414.6 EKX53434.1 - 4.6e-15 55.0 0.1 3.1e-07 30.0 0.0 3.6 3 0 0 3 3 3 2 TPR repeat TPR_16 PF13432.6 EKX53434.1 - 5.6e-14 52.5 2.0 5.8e-06 26.9 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX53434.1 - 8.8e-14 50.4 6.0 0.00011 22.0 0.1 6.2 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 EKX53434.1 - 2.3e-12 46.4 0.3 0.6 10.6 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX53434.1 - 7.5e-10 38.2 2.0 0.0031 17.3 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX53434.1 - 6.6e-09 35.3 0.6 0.014 15.6 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX53434.1 - 1.1e-08 35.2 1.5 0.0061 17.3 0.1 5.3 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX53434.1 - 3.1e-06 27.6 0.8 0.045 14.3 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX53434.1 - 2.3e-05 24.6 5.3 0.18 12.1 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX53434.1 - 5.9e-05 23.2 0.5 0.57 10.4 0.1 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EKX53434.1 - 0.0022 18.1 0.2 0.41 10.8 0.0 3.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX53434.1 - 0.047 13.6 6.0 2.3 8.2 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EKX53434.1 - 0.1 12.7 0.2 6.4 7.0 0.0 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat UQ_con PF00179.26 EKX53436.1 - 6.2e-44 149.0 0.0 7e-44 148.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 EKX53436.1 - 0.1 12.2 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 APG6_N PF17675.1 EKX53437.1 - 1.2e-09 38.8 12.1 1.2e-09 38.8 12.1 1.9 2 0 0 2 2 2 1 Apg6 coiled-coil region HIP1_clath_bdg PF16515.5 EKX53437.1 - 0.013 16.1 5.7 0.013 16.1 5.7 2.0 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CaM_binding PF07839.11 EKX53437.1 - 0.16 12.7 3.9 5.3 7.8 2.2 2.1 2 0 0 2 2 2 0 Plant calmodulin-binding domain Tho2 PF11262.8 EKX53437.1 - 1.3 8.1 6.4 0.85 8.8 4.7 1.5 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 APG6 PF04111.12 EKX53438.1 - 2.1e-66 223.3 0.0 2.4e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 Apg6 BARA domain YqaJ PF09588.10 EKX53439.1 - 2.6e-21 76.3 0.0 6.7e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain Ribosomal_60s PF00428.19 EKX53439.1 - 0.018 15.6 0.7 0.018 15.6 0.7 2.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein Phage_Gp23 PF10669.9 EKX53439.1 - 0.48 10.8 3.3 1.5 9.2 3.3 1.8 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) PTPRCAP PF15713.5 EKX53439.1 - 1.7 8.9 16.4 5.1 7.4 16.4 1.9 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Presenilin PF01080.17 EKX53439.1 - 3.7 6.2 4.2 5.8 5.6 4.2 1.2 1 0 0 1 1 1 0 Presenilin PAC1 PF16094.5 EKX53439.1 - 7.7 5.6 12.0 37 3.4 0.0 2.2 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 TPR_1 PF00515.28 EKX53440.1 - 1.7e-14 52.9 3.3 7.6e-05 22.4 0.0 6.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 EKX53440.1 - 2.4e-11 42.8 1.8 0.0018 18.3 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX53440.1 - 1.8e-09 37.8 1.0 0.00084 19.6 0.1 4.3 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX53440.1 - 5.5e-08 32.4 0.2 0.00021 20.9 0.1 4.4 4 0 0 4 4 4 1 TPR repeat TPR_16 PF13432.6 EKX53440.1 - 2.5e-06 28.0 0.1 0.11 13.1 0.0 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX53440.1 - 3.3e-06 26.8 2.9 0.13 12.2 0.1 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX53440.1 - 2.2e-05 24.3 14.1 1.7 9.0 0.2 6.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_15 PF13429.6 EKX53440.1 - 8.7e-05 21.9 1.7 0.00017 20.9 0.2 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX53440.1 - 0.0011 19.1 0.2 0.034 14.3 0.0 3.1 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX53440.1 - 0.0015 19.2 1.0 23 6.2 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX53440.1 - 0.0028 18.1 9.3 3 8.4 0.3 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX53440.1 - 0.0049 16.8 0.1 0.18 11.9 0.1 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat FAT PF02259.23 EKX53440.1 - 0.0062 15.8 0.3 0.23 10.6 0.1 2.1 2 0 0 2 2 2 1 FAT domain TPR_17 PF13431.6 EKX53440.1 - 0.028 14.8 0.2 54 4.5 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3015 PF11220.8 EKX53440.1 - 0.1 12.5 0.6 8.1 6.3 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3015) SHNi-TPR PF10516.9 EKX53440.1 - 0.28 10.7 1.1 16 5.0 0.2 2.6 2 0 0 2 2 2 0 SHNi-TPR TPR_6 PF13174.6 EKX53440.1 - 2.1 9.1 14.4 29 5.6 0.4 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF2462 PF09495.10 EKX53441.1 - 1.6e-12 48.0 10.8 1.8e-12 47.8 10.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) CsgF PF10614.9 EKX53441.1 - 0.047 13.9 0.2 0.052 13.8 0.2 1.1 1 0 0 1 1 1 0 Type VIII secretion system (T8SS), CsgF protein Sterile PF03015.19 EKX53441.1 - 0.064 13.5 0.1 0.075 13.3 0.1 1.1 1 0 0 1 1 1 0 Male sterility protein Glyco_hydro_77 PF02446.17 EKX53442.1 - 7.6e-73 245.9 2.3 7.1e-72 242.7 2.3 2.0 1 1 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.19 EKX53442.1 - 8.6e-16 57.6 0.0 1.9e-11 43.7 0.1 2.6 2 0 0 2 2 2 2 Starch binding domain Med21 PF11221.8 EKX53448.1 - 1.1 9.5 5.1 0.97 9.7 3.3 1.8 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Clathrin PF00637.20 EKX53449.1 - 4.5e-13 49.3 14.0 7.7e-06 25.8 0.0 7.3 5 2 1 7 7 6 3 Region in Clathrin and VPS Coatomer_WDAD PF04053.14 EKX53449.1 - 6.4e-10 38.7 10.9 0.0017 17.5 0.1 4.9 3 2 2 5 5 5 3 Coatomer WD associated region WD40 PF00400.32 EKX53449.1 - 0.0002 22.1 4.7 7.5 7.6 0.0 5.3 5 0 0 5 5 5 1 WD domain, G-beta repeat TPR_14 PF13428.6 EKX53449.1 - 0.0012 19.5 13.7 0.31 12.0 0.0 7.8 10 1 1 11 11 9 1 Tetratricopeptide repeat Hira PF07569.11 EKX53449.1 - 0.0026 17.5 0.1 0.017 14.9 0.0 2.3 2 0 0 2 2 2 1 TUP1-like enhancer of split TPR_7 PF13176.6 EKX53449.1 - 0.0062 16.5 19.9 2 8.7 0.3 8.7 9 1 1 10 10 10 2 Tetratricopeptide repeat Vps39_1 PF10366.9 EKX53449.1 - 0.0083 16.4 5.5 1.5 9.1 0.1 4.0 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Mcl1_mid PF12341.8 EKX53449.1 - 0.012 15.0 0.4 1 8.6 0.1 2.4 2 0 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region DUF2624 PF11116.8 EKX53449.1 - 0.013 16.4 0.2 0.062 14.2 0.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) DUF410 PF04190.13 EKX53449.1 - 0.015 15.1 4.1 0.42 10.4 0.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF410) Utp13 PF08625.11 EKX53449.1 - 0.075 12.9 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain DS PF01916.17 EKX53449.1 - 0.1 11.8 0.2 0.4 9.9 0.1 1.8 1 1 0 2 2 2 0 Deoxyhypusine synthase TPR_2 PF07719.17 EKX53449.1 - 0.13 12.4 31.1 0.18 12.0 1.0 9.4 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX53449.1 - 0.46 10.8 20.8 0.3 11.4 0.7 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF2301 PF10063.9 EKX53450.1 - 1.1e-42 145.7 1.8 1.7e-42 145.1 0.6 1.8 2 0 0 2 2 2 1 Uncharacterized integral membrane protein (DUF2301) LRR_8 PF13855.6 EKX53451.1 - 3.2e-63 209.4 58.9 2.7e-14 52.6 2.6 5.6 2 2 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 EKX53451.1 - 1.3e-29 101.7 29.6 7e-08 32.7 0.3 6.4 3 1 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX53451.1 - 3.5e-16 59.3 0.0 2.7e-08 33.8 0.0 2.2 2 0 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EKX53451.1 - 1.6e-09 37.0 29.7 0.35 11.6 0.1 10.0 10 1 1 11 11 11 3 Leucine Rich Repeat LRR_9 PF14580.6 EKX53451.1 - 5.2e-08 32.6 2.2 0.0051 16.3 0.1 3.7 1 1 4 5 5 5 5 Leucine-rich repeat PrmA PF06325.13 EKX53452.1 - 8.3e-10 38.5 0.0 1.2e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 EKX53452.1 - 2.9e-05 23.9 0.0 5.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 EKX53452.1 - 0.0042 17.8 0.0 0.054 14.2 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.7 EKX53452.1 - 0.0049 16.8 0.0 0.0095 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX53452.1 - 0.015 15.9 0.1 1.2 9.8 0.0 3.1 3 0 0 3 3 3 0 Methyltransferase domain PCMT PF01135.19 EKX53452.1 - 0.019 14.7 0.2 0.036 13.8 0.2 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EKX53452.1 - 0.023 14.2 0.0 0.26 10.8 0.1 2.4 3 0 0 3 3 3 0 Methyltransferase small domain RrnaAD PF00398.20 EKX53452.1 - 0.027 13.5 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 EKX53452.1 - 0.068 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UPF0242 PF06785.11 EKX53453.1 - 0.0049 17.0 7.3 0.0049 17.0 7.3 3.5 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus XLF PF09302.11 EKX53453.1 - 0.021 15.0 3.2 0.021 15.0 3.2 2.7 1 1 1 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Mce4_CUP1 PF11887.8 EKX53453.1 - 0.073 12.5 0.9 0.2 11.0 0.0 2.1 2 2 1 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF1993 PF09351.10 EKX53453.1 - 0.16 12.1 5.0 0.054 13.6 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) OmpH PF03938.14 EKX53453.1 - 0.22 11.9 20.5 0.18 12.1 5.1 3.1 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) Spc7 PF08317.11 EKX53453.1 - 1.4 7.7 34.7 0.97 8.2 15.6 2.3 1 1 0 2 2 2 0 Spc7 kinetochore protein CSN5_C PF18323.1 EKX53453.1 - 2.5 9.0 12.4 3.9 8.4 0.1 3.9 3 1 0 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain ERM PF00769.19 EKX53453.1 - 4.7 7.0 37.6 0.043 13.6 8.2 3.0 1 1 2 3 3 3 0 Ezrin/radixin/moesin family AAA_26 PF13500.6 EKX53454.1 - 1.2e-40 139.5 0.0 1.7e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EKX53454.1 - 6e-06 26.3 0.0 1.3e-05 25.3 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain DRTGG PF07085.12 EKX53454.1 - 1.7e-05 24.5 0.0 3.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 DRTGG domain NHL PF01436.21 EKX53455.1 - 2.6e-30 102.9 11.0 3.9e-06 26.6 0.0 6.3 6 0 0 6 6 6 5 NHL repeat SGL PF08450.12 EKX53455.1 - 4.6e-15 55.9 0.0 4.4e-07 29.7 0.0 3.3 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region Phytase-like PF13449.6 EKX53455.1 - 0.0066 16.4 0.0 3.4 7.5 0.0 3.5 2 1 2 4 4 4 2 Esterase-like activity of phytase Reg_prop PF07494.11 EKX53455.1 - 0.14 12.5 0.1 13 6.4 0.1 3.6 2 1 1 3 3 3 0 Two component regulator propeller DUF3482 PF11981.8 EKX53456.1 - 0.0025 17.3 1.5 0.0048 16.3 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3482) TAF4 PF05236.14 EKX53456.1 - 0.0052 16.6 7.3 0.034 13.9 0.1 2.9 2 1 0 3 3 3 2 Transcription initiation factor TFIID component TAF4 family SAGA-Tad1 PF12767.7 EKX53456.1 - 0.012 15.4 0.2 0.018 14.8 0.2 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit SpoIIIAH PF12685.7 EKX53456.1 - 0.11 12.3 1.7 0.17 11.7 1.7 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein WD40 PF00400.32 EKX53457.1 - 4.9e-09 36.7 14.8 0.00079 20.2 0.0 6.4 6 1 0 6 6 6 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 EKX53457.1 - 0.022 13.3 0.8 0.13 10.8 0.0 2.5 3 0 0 3 3 3 0 Cytochrome D1 heme domain PQQ_3 PF13570.6 EKX53457.1 - 0.07 13.6 0.6 4.9 7.8 0.2 3.4 3 0 0 3 3 3 0 PQQ-like domain Tetraspanin PF00335.20 EKX53458.1 - 3.1e-05 23.8 25.5 0.0021 17.8 25.5 3.4 1 1 0 1 1 1 1 Tetraspanin family Phage_holin_3_6 PF07332.11 EKX53458.1 - 3.3 7.8 10.5 0.28 11.2 1.2 2.8 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Peptidase_S28 PF05577.12 EKX53459.1 - 4.2e-42 144.4 0.0 2.4e-34 118.9 0.0 2.2 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 EKX53459.1 - 0.004 16.8 0.1 0.0097 15.6 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2920 PF11144.8 EKX53459.1 - 0.014 14.6 0.2 0.053 12.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Peptidase_S37 PF05576.11 EKX53459.1 - 0.018 13.7 0.0 0.025 13.2 0.0 1.2 1 0 0 1 1 1 0 PS-10 peptidase S37 Abhydrolase_6 PF12697.7 EKX53459.1 - 0.087 13.4 0.2 0.17 12.5 0.2 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family UvrA_DNA-bind PF17755.1 EKX53459.1 - 0.21 12.0 0.0 0.42 11.0 0.0 1.4 1 0 0 1 1 1 0 UvrA DNA-binding domain DNA_pol_D_N PF18018.1 EKX53460.1 - 2.6 8.2 9.8 0.3 11.2 2.6 2.9 2 2 0 2 2 2 0 DNA polymerase delta subunit OB-fold domain 2-oxoacid_dh PF00198.23 EKX53461.1 - 4.9e-80 268.3 0.3 5.4e-80 268.2 0.3 1.0 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Cupin_4 PF08007.12 EKX53462.1 - 1.5e-08 34.5 0.0 2.1e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 EKX53462.1 - 0.0013 18.5 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 Cupin-like domain Cupin_3 PF05899.12 EKX53462.1 - 0.07 12.8 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF861) SH3_2 PF07653.17 EKX53464.1 - 2.8e-06 26.9 0.2 5.1e-06 26.1 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EKX53464.1 - 3.1e-05 23.5 0.1 0.00023 20.7 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EKX53464.1 - 0.0068 16.3 0.3 0.029 14.2 0.3 2.0 1 1 0 1 1 1 1 Variant SH3 domain AMPK1_CBM PF16561.5 EKX53464.1 - 0.077 13.2 0.1 0.18 12.0 0.0 1.6 2 0 0 2 2 2 0 Glycogen recognition site of AMP-activated protein kinase PDGF_N PF04692.13 EKX53464.1 - 0.24 12.2 2.0 0.77 10.6 0.1 2.3 2 0 0 2 2 2 0 Platelet-derived growth factor, N terminal region Exo_endo_phos PF03372.23 EKX53466.1 - 2e-14 53.7 0.0 1.6e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family JAB PF01398.21 EKX53467.1 - 8.5e-33 112.8 0.0 2e-32 111.6 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EKX53467.1 - 2.6e-13 50.3 0.6 5.1e-13 49.4 0.6 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EKX53467.1 - 3.9e-06 26.6 0.0 7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain PGM_PMM_II PF02879.16 EKX53467.1 - 0.012 16.2 0.1 0.13 12.9 0.0 2.2 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DUF4525 PF15027.6 EKX53467.1 - 0.048 13.4 0.1 0.082 12.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) Flu_M1_C PF08289.11 EKX53469.1 - 0.0096 16.1 2.0 0.18 12.0 0.2 2.2 1 1 1 2 2 2 2 Influenza Matrix protein (M1) C-terminal domain Choline_transpo PF04515.12 EKX53473.1 - 0.00011 21.6 12.6 0.0098 15.1 1.8 3.1 2 1 0 3 3 3 2 Plasma-membrane choline transporter DUF3742 PF12553.8 EKX53473.1 - 0.6 10.2 2.0 2.3 8.4 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3742) SSF PF00474.17 EKX53474.1 - 1.8e-17 63.3 25.5 2.6e-17 62.8 25.5 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family VPS13 PF16908.5 EKX53475.1 - 2.2e-53 181.5 1.2 3e-53 181.1 1.2 1.2 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 EKX53475.1 - 1.7e-30 105.5 1.6 2.3e-30 105.1 0.3 1.8 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 rve_3 PF13683.6 EKX53475.1 - 0.18 11.6 0.5 1.5 8.7 0.1 2.7 3 0 0 3 3 3 0 Integrase core domain TRIC PF05197.13 EKX53476.1 - 0.0076 15.8 0.3 0.018 14.6 0.3 1.6 1 0 0 1 1 1 1 TRIC channel DUF5336 PF17270.2 EKX53476.1 - 0.028 14.1 0.0 0.078 12.6 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5336) FG-GAP_2 PF14312.6 EKX53479.1 - 6.6e-30 103.1 12.1 3e-08 33.8 0.0 7.4 7 0 0 7 7 7 6 FG-GAP repeat FHA PF00498.26 EKX53480.1 - 0.0013 19.0 0.0 0.0023 18.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 EKX53480.1 - 0.067 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 FHA domain Yop-YscD_cpl PF16697.5 EKX53480.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain PDZ PF00595.24 EKX53481.1 - 4.7e-20 71.7 1.1 7.4e-06 26.2 0.0 3.5 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 EKX53481.1 - 4.6e-19 68.0 4.1 2.1e-05 24.2 0.0 3.8 4 0 0 4 4 4 3 PDZ domain PDZ_2 PF13180.6 EKX53481.1 - 1.6e-10 41.2 0.3 0.037 14.3 0.0 4.3 4 0 0 4 4 4 3 PDZ domain PDZ_4 PF17816.1 EKX53481.1 - 0.00087 19.7 0.0 1.7 9.1 0.0 3.1 3 0 0 3 3 3 2 PDZ domain Tricorn_PDZ PF14685.6 EKX53481.1 - 0.00095 19.1 0.3 0.75 9.8 0.0 3.4 3 0 0 3 3 3 1 Tricorn protease PDZ domain CBF_beta PF02312.17 EKX53481.1 - 0.023 14.3 0.0 0.057 13.1 0.0 1.6 1 0 0 1 1 1 0 Core binding factor beta subunit Surp PF01805.20 EKX53482.1 - 2.1e-25 88.4 1.0 1.4e-12 47.4 0.1 2.8 3 0 0 3 3 3 2 Surp module DRY_EERY PF09750.9 EKX53482.1 - 1.3e-21 77.2 0.4 1.3e-21 77.2 0.4 3.0 3 1 0 3 3 3 1 Alternative splicing regulator ATF7IP_BD PF16788.5 EKX53482.1 - 0.0097 16.0 2.3 0.0097 16.0 2.3 2.7 3 0 0 3 3 3 1 ATF-interacting protein binding domain Toprim_Crpt PF13342.6 EKX53482.1 - 0.015 15.3 0.5 5.7 7.0 0.0 2.7 2 0 0 2 2 2 0 C-terminal repeat of topoisomerase Lipase_3 PF01764.25 EKX53484.1 - 2.4e-28 98.8 0.0 5.5e-28 97.6 0.0 1.6 1 1 0 1 1 1 1 Lipase (class 3) MIG-14_Wnt-bd PF06664.12 EKX53484.1 - 5.7e-18 65.2 20.1 9.3e-18 64.5 20.1 1.3 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion Abhydrolase_6 PF12697.7 EKX53484.1 - 0.025 15.2 0.0 0.057 14.0 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EKX53484.1 - 0.12 11.6 0.0 0.51 9.6 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF2345 PF10106.9 EKX53485.1 - 0.00014 21.7 2.4 0.054 13.4 0.4 2.1 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2345) DUF5043 PF16446.5 EKX53485.1 - 0.002 18.1 1.7 6.1 6.8 0.1 3.4 1 1 2 3 3 3 3 Domain of unknown function (DUF5043) TMEMspv1-c74-12 PF11044.8 EKX53485.1 - 0.0081 16.1 8.9 46 4.1 0.1 5.0 1 1 2 3 3 3 1 Plectrovirus spv1-c74 ORF 12 transmembrane protein AAA PF00004.29 EKX53486.1 - 3e-11 43.9 0.0 2.6e-10 40.8 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EKX53486.1 - 2.2e-09 37.7 0.0 4.9e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EKX53486.1 - 6.9e-09 36.3 0.0 8.7e-07 29.5 0.0 2.5 1 1 0 2 2 2 1 AAA ATPase domain AAA_lid_10 PF17872.1 EKX53486.1 - 1e-08 35.2 0.2 2.3e-08 34.0 0.2 1.5 1 0 0 1 1 1 1 AAA lid domain BAH PF01426.18 EKX53486.1 - 1.7e-06 27.8 0.0 4.1e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 BAH domain NACHT PF05729.12 EKX53486.1 - 0.0039 17.1 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 EKX53486.1 - 0.0044 17.3 0.1 0.024 15.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 EKX53486.1 - 0.0065 15.6 0.0 0.016 14.2 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_32 PF13654.6 EKX53486.1 - 0.026 13.3 0.2 1.4 7.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EKX53486.1 - 0.037 13.3 0.0 0.08 12.2 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 EKX53486.1 - 0.045 13.5 0.0 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EKX53486.1 - 0.05 13.3 0.0 0.12 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 EKX53486.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RuvB_N PF05496.12 EKX53486.1 - 0.14 11.9 0.0 0.54 10.0 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EKX53486.1 - 0.17 11.1 0.1 0.37 10.0 0.0 1.5 2 0 0 2 2 2 0 TIP49 P-loop domain NifU_N PF01592.16 EKX53487.1 - 4.2e-54 182.1 0.2 5.1e-54 181.8 0.2 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain LRR_6 PF13516.6 EKX53489.1 - 3.8e-22 76.4 14.2 0.00019 21.2 0.0 7.2 8 0 0 8 8 8 5 Leucine Rich repeat LRR_1 PF00560.33 EKX53489.1 - 8.7e-07 28.6 6.8 9.9 7.2 0.0 6.1 6 1 0 6 6 6 3 Leucine Rich Repeat LRR_4 PF12799.7 EKX53489.1 - 2.3e-05 24.7 9.6 1.7 9.2 0.1 5.3 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX53489.1 - 0.00014 21.5 8.7 0.11 12.3 0.2 4.5 3 2 0 3 3 3 2 Leucine rich repeat EF-hand_1 PF00036.32 EKX53490.1 - 2e-17 61.3 1.6 3.5e-09 35.6 0.2 2.1 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX53490.1 - 5.3e-15 55.0 3.4 9.6e-12 44.6 0.3 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX53490.1 - 4.2e-14 51.3 0.9 1.3e-06 27.7 0.2 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX53490.1 - 2.6e-13 50.2 0.1 3e-13 50.0 0.1 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX53490.1 - 4.5e-12 44.9 0.3 3.4e-05 23.4 0.1 2.2 1 1 1 2 2 2 2 EF-hand domain EF-hand_9 PF14658.6 EKX53490.1 - 0.00011 22.5 0.0 0.00013 22.3 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain DUF1949 PF09186.11 EKX53490.1 - 0.05 13.5 0.1 0.079 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1949) EF-hand_4 PF12763.7 EKX53490.1 - 0.088 12.8 0.2 3.5 7.6 0.0 2.0 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Ank_2 PF12796.7 EKX53491.1 - 2.7e-11 43.9 0.3 6.1e-11 42.8 0.3 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX53491.1 - 5.6e-09 36.4 0.7 0.00054 20.5 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX53491.1 - 6.2e-09 35.4 0.2 0.028 14.9 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EKX53491.1 - 6.4e-08 32.7 1.9 0.00032 20.9 0.1 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX53491.1 - 5.5e-05 23.4 3.2 0.076 13.5 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Pkinase PF00069.25 EKX53492.1 - 2.7e-61 207.3 0.0 3.5e-61 206.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX53492.1 - 1.2e-38 132.8 0.0 1.7e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_2 PF07719.17 EKX53492.1 - 9.2e-10 37.9 4.3 2.7e-05 23.9 0.4 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX53492.1 - 2.9e-08 33.3 1.3 0.017 15.3 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX53492.1 - 6.6e-08 33.1 1.5 7.5e-06 26.5 0.8 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX53492.1 - 5.6e-07 29.1 3.5 0.00018 21.2 0.3 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX53492.1 - 4.9e-06 26.6 1.8 0.1 13.0 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX53492.1 - 6.3e-06 26.6 1.2 0.057 14.3 0.2 4.0 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX53492.1 - 1.8e-05 25.1 0.7 0.01 16.3 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX53492.1 - 5.1e-05 23.0 1.5 0.084 12.9 0.3 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX53492.1 - 0.0019 18.3 1.3 0.62 10.2 0.2 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX53492.1 - 0.0026 18.0 7.6 0.15 12.3 2.4 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat Pkinase_fungal PF17667.1 EKX53492.1 - 0.0028 16.5 0.1 0.0083 14.9 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase TPR_10 PF13374.6 EKX53492.1 - 0.026 14.4 8.0 0.57 10.1 1.4 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat APH PF01636.23 EKX53492.1 - 0.029 14.3 0.1 0.059 13.3 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Coatomer_E PF04733.14 EKX53492.1 - 0.034 13.6 0.1 0.27 10.6 0.0 2.4 2 1 1 3 3 3 0 Coatomer epsilon subunit Kinase-like PF14531.6 EKX53492.1 - 0.046 13.0 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 EKX53492.1 - 0.13 11.9 0.1 0.31 10.6 0.1 1.6 1 0 0 1 1 1 0 RIO1 family Sel1 PF08238.12 EKX53492.1 - 0.44 11.3 1.9 36 5.2 0.2 2.7 2 0 0 2 2 2 0 Sel1 repeat TPR_3 PF07720.12 EKX53492.1 - 9.5 6.3 6.6 27 4.9 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Emaravirus_P4 PF16505.5 EKX53493.1 - 0.079 12.0 0.0 0.084 11.9 0.0 1.0 1 0 0 1 1 1 0 P4 movement protein of Emaravirus, and the 30K superfamily DUF3591 PF12157.8 EKX53494.1 - 1e-75 255.1 0.3 1e-75 255.1 0.3 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) Glycos_transf_1 PF00534.20 EKX53495.1 - 1.2e-36 125.8 0.0 1.9e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EKX53495.1 - 1e-27 97.2 0.0 2e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 AMPK1_CBM PF16561.5 EKX53495.1 - 3e-20 72.2 0.0 6.9e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Glyco_transf_4 PF13439.6 EKX53495.1 - 1.9e-17 63.8 1.0 6.1e-17 62.1 1.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EKX53495.1 - 2.1e-15 57.5 0.8 4.5e-15 56.5 0.8 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EKX53495.1 - 4.3e-09 36.7 0.0 8.8e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 EKX53495.1 - 1.2e-08 34.9 0.7 1.1e-07 31.8 0.0 2.1 1 1 1 2 2 2 1 Starch synthase catalytic domain CBM53 PF16760.5 EKX53495.1 - 0.016 15.8 0.0 0.05 14.2 0.0 1.9 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) LRR_9 PF14580.6 EKX53496.1 - 1.4e-10 41.0 1.0 1.8e-10 40.6 1.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EKX53496.1 - 3.1e-10 40.2 10.0 2.6e-05 24.5 0.4 3.0 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX53496.1 - 2.7e-08 33.4 7.0 1.4e-07 31.1 2.4 3.0 1 1 2 3 3 3 2 Leucine rich repeat Mannitol_dh PF01232.23 EKX53496.1 - 0.039 14.1 0.0 0.052 13.7 0.0 1.2 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain LRR_6 PF13516.6 EKX53496.1 - 1.5 9.0 4.8 44 4.5 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeat ANAPC2 PF08672.11 EKX53498.1 - 1.9e-20 73.1 0.4 3.9e-20 72.1 0.4 1.6 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Cullin PF00888.22 EKX53498.1 - 1.9e-16 59.8 0.0 2.8e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Cullin family ACPS PF01648.20 EKX53499.1 - 1e-12 48.2 0.0 7.4e-12 45.4 0.0 2.3 2 1 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily FAM176 PF14851.6 EKX53499.1 - 0.14 11.8 0.9 0.44 10.2 1.2 1.6 2 0 0 2 2 2 0 FAM176 family CDC45 PF02724.14 EKX53499.1 - 0.3 9.3 4.4 0.38 9.0 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 EKX53499.1 - 3.7 5.5 15.9 5 5.1 15.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 EKX53499.1 - 4.5 5.4 8.3 5.9 5.0 8.3 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EKX53499.1 - 6.3 6.1 8.2 8.5 5.7 8.2 1.1 1 0 0 1 1 1 0 SDA1 AOX PF01786.17 EKX53500.1 - 7e-29 101.0 1.9 9.8e-29 100.5 1.9 1.2 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.13 EKX53500.1 - 0.15 11.8 0.5 0.28 10.9 0.5 1.5 1 1 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 Pkinase PF00069.25 EKX53501.1 - 0.00012 21.5 1.3 0.00027 20.4 0.1 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX53501.1 - 0.0025 17.1 0.5 0.0058 16.0 0.5 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase IQ PF00612.27 EKX53501.1 - 0.0046 16.6 14.9 0.1 12.4 0.0 4.0 4 0 0 4 4 4 2 IQ calmodulin-binding motif DZR PF12773.7 EKX53501.1 - 0.17 11.9 0.3 0.37 10.9 0.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 EKX53501.1 - 2.9 7.7 4.2 6.1 6.7 4.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain UPRTase PF14681.6 EKX53502.1 - 6.5e-64 215.2 0.0 8.4e-64 214.8 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EKX53502.1 - 4.7e-09 36.0 0.1 8e-09 35.2 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain NT5C PF06941.12 EKX53502.1 - 0.03 14.2 0.0 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) tRNA-synt_1 PF00133.22 EKX53504.1 - 1.1e-32 113.2 0.0 1.1e-17 63.5 0.0 2.8 2 2 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EKX53504.1 - 8.1e-19 67.6 0.2 2.7e-12 46.1 0.0 4.2 3 1 1 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EKX53504.1 - 1.5e-12 47.7 0.3 6.6e-12 45.6 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EKX53504.1 - 3.4e-08 33.2 0.2 8.6e-08 31.9 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EKX53504.1 - 0.01 14.8 0.0 0.026 13.4 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (K) HEAT PF02985.22 EKX53505.1 - 2.1e-38 127.0 29.0 0.013 15.7 0.0 20.0 21 0 0 21 21 20 8 HEAT repeat HEAT_EZ PF13513.6 EKX53505.1 - 1.8e-30 104.9 46.0 0.00011 22.6 0.2 17.2 16 4 5 21 21 19 9 HEAT-like repeat HEAT_2 PF13646.6 EKX53505.1 - 9.9e-29 99.6 37.2 9.4e-06 25.9 0.2 14.4 8 4 6 15 15 15 9 HEAT repeats Vac14_Fab1_bd PF12755.7 EKX53505.1 - 1.3e-19 70.6 0.0 0.22 12.2 0.0 9.5 7 2 3 10 10 10 4 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EKX53505.1 - 3.2e-15 56.3 0.1 1.3e-05 24.8 0.0 6.9 5 3 1 6 6 6 2 CLASP N terminal Cnd1 PF12717.7 EKX53505.1 - 5.8e-11 42.7 1.0 4.2 7.4 0.0 8.3 6 3 3 9 9 8 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 EKX53505.1 - 1.1e-10 41.2 2.3 0.011 14.8 0.0 8.1 5 2 3 8 8 8 2 RNAPII transcription regulator C-terminal Adaptin_N PF01602.20 EKX53505.1 - 1.1e-08 34.2 4.7 1.4 7.4 0.0 7.7 4 3 1 6 6 6 2 Adaptin N terminal region IFRD PF05004.13 EKX53505.1 - 6.2e-08 32.1 6.1 0.035 13.2 0.3 5.8 6 2 0 6 6 6 2 Interferon-related developmental regulator (IFRD) ParcG PF10274.9 EKX53505.1 - 2.2e-07 31.2 1.3 0.28 11.3 0.0 6.6 5 1 1 6 6 6 1 Parkin co-regulated protein UME PF08064.13 EKX53505.1 - 2.9e-07 30.3 3.4 1.4 8.9 0.0 8.5 7 3 1 9 9 8 1 UME (NUC010) domain TAF6_C PF07571.13 EKX53505.1 - 3.2e-07 30.6 0.3 0.084 13.2 0.1 7.1 7 2 0 8 8 8 1 TAF6 C-terminal HEAT repeat domain Arm PF00514.23 EKX53505.1 - 1.8e-06 27.8 5.6 0.16 12.0 0.0 8.5 10 1 1 11 11 9 1 Armadillo/beta-catenin-like repeat DUF3437 PF11919.8 EKX53505.1 - 5.4e-05 23.0 0.6 0.42 10.6 0.0 6.2 6 1 1 7 7 6 1 Domain of unknown function (DUF3437) Tti2 PF10521.9 EKX53505.1 - 9.9e-05 22.0 0.1 12 5.3 0.0 6.4 6 3 2 8 8 8 0 Tti2 family Ecm29 PF13001.7 EKX53505.1 - 0.00014 20.7 1.3 0.56 8.8 0.0 5.0 7 1 0 7 7 7 1 Proteasome stabiliser Cohesin_HEAT PF12765.7 EKX53505.1 - 0.00025 21.3 3.1 16 5.9 0.0 5.8 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion Dopey_N PF04118.14 EKX53505.1 - 0.00032 19.9 0.1 1.1 8.3 0.0 4.1 4 2 1 5 5 5 2 Dopey, N-terminal TFCD_C PF12612.8 EKX53505.1 - 0.001 19.0 0.5 0.55 10.0 0.0 3.8 4 0 0 4 4 4 1 Tubulin folding cofactor D C terminal DUF3535 PF12054.8 EKX53505.1 - 0.0047 16.2 5.4 1.3 8.2 0.0 4.6 3 2 0 4 4 4 1 Domain of unknown function (DUF3535) MMS19_N PF14500.6 EKX53505.1 - 0.0061 16.2 5.2 4.5 6.8 0.0 5.3 4 2 3 7 7 6 1 Dos2-interacting transcription regulator of RNA-Pol-II Ipi1_N PF12333.8 EKX53505.1 - 0.02 15.5 0.0 10 6.8 0.0 5.1 6 0 0 6 6 5 0 Rix1 complex component involved in 60S ribosome maturation FANCI_S2 PF14676.6 EKX53505.1 - 0.034 14.4 1.2 0.98 9.7 0.2 3.6 3 1 0 3 3 2 0 FANCI solenoid 2 NUC173 PF08161.12 EKX53505.1 - 0.057 13.1 4.2 29 4.2 0.0 5.0 6 1 1 7 7 7 0 NUC173 domain SpoU_methylase PF00588.19 EKX53506.1 - 2.6e-26 92.5 0.0 4.6e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family Hydrolase_4 PF12146.8 EKX53507.1 - 1.8e-09 37.2 0.0 2.1e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EKX53507.1 - 0.00012 21.8 0.1 0.00014 21.5 0.1 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 EKX53507.1 - 0.00069 19.3 0.2 0.00086 19.0 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EKX53507.1 - 0.011 16.4 0.1 0.013 16.1 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family BAAT_C PF08840.11 EKX53507.1 - 0.025 14.5 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase_3 PF01764.25 EKX53507.1 - 0.043 13.7 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.11 EKX53507.1 - 0.043 13.1 0.0 0.27 10.5 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) CLU PF13236.6 EKX53508.1 - 2.2e-67 227.1 0.0 4.2e-67 226.2 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 EKX53508.1 - 7.5e-17 61.9 0.3 9.8e-14 51.8 0.0 2.6 1 1 1 2 2 2 2 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 EKX53508.1 - 3.4e-16 59.3 9.5 9.7e-08 32.2 0.1 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 EKX53508.1 - 7.3e-14 51.1 5.6 3.3e-05 23.6 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat CLU_N PF15044.6 EKX53508.1 - 7.4e-13 48.7 0.3 2e-12 47.3 0.3 1.8 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_2 PF07719.17 EKX53508.1 - 1.4e-07 31.1 11.3 0.03 14.4 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX53508.1 - 2.4e-05 23.9 7.2 0.031 13.7 1.6 2.3 1 1 0 2 2 2 2 MalT-like TPR region TPR_1 PF00515.28 EKX53508.1 - 6.6e-05 22.6 9.8 0.13 12.1 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX53508.1 - 0.0068 16.4 3.4 1.1 9.5 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX53508.1 - 0.0089 16.2 0.6 0.88 9.8 0.0 3.3 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX53508.1 - 0.009 16.2 8.4 0.39 11.0 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat RCC1 PF00415.18 EKX53509.1 - 4.2e-60 200.2 21.8 1.4e-14 54.4 0.0 5.6 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX53509.1 - 2.1e-27 94.3 31.6 1.3e-07 31.2 1.5 5.4 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat Peptidase_C25_C PF03785.14 EKX53509.1 - 0.16 11.8 0.0 26 4.7 0.0 2.5 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain HA PF03457.14 EKX53510.1 - 2.2e-23 82.3 3.6 8.5e-12 45.2 0.1 2.2 2 0 0 2 2 2 2 Helicase associated domain Redoxin PF08534.10 EKX53511.1 - 7.1e-26 90.7 0.0 9.1e-26 90.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EKX53511.1 - 3.5e-11 43.1 0.0 4.4e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family CtnDOT_TraJ PF07863.11 EKX53511.1 - 0.11 13.2 0.1 3.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Homologues of TraJ from Bacteroides conjugative transposon Imm47 PF15573.6 EKX53511.1 - 0.12 11.9 0.1 0.15 11.6 0.1 1.1 1 0 0 1 1 1 0 Immunity protein 47 Xpo1 PF08389.12 EKX53512.1 - 1.7e-11 44.4 0.0 2.3e-10 40.7 0.0 2.6 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 EKX53512.1 - 0.0047 16.8 0.0 0.018 14.9 0.0 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Epimerase PF01370.21 EKX53513.1 - 8.3e-23 81.1 0.2 3.2e-21 75.9 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EKX53513.1 - 5.9e-20 71.4 0.8 8.2e-20 70.9 0.8 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EKX53513.1 - 2.4e-15 56.8 0.1 4.4e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EKX53513.1 - 5.4e-15 55.3 1.8 8.7e-11 41.5 1.8 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EKX53513.1 - 2e-14 53.9 0.6 3.2e-14 53.2 0.2 1.5 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EKX53513.1 - 2.4e-06 27.3 0.4 6.5e-06 25.9 0.4 1.8 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 EKX53513.1 - 4.1e-05 22.9 1.4 9.3e-05 21.7 1.4 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EKX53513.1 - 8.4e-05 21.8 0.3 0.00015 21.0 0.1 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.10 EKX53513.1 - 0.0048 16.8 1.4 0.025 14.5 1.4 2.1 1 1 0 1 1 1 1 KR domain NAD_binding_2 PF03446.15 EKX53513.1 - 0.019 15.1 0.1 0.053 13.7 0.1 1.8 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_transf_4 PF13439.6 EKX53513.1 - 0.07 13.1 0.8 0.31 11.0 0.5 2.2 1 1 1 2 2 2 0 Glycosyltransferase Family 4 Radical_SAM PF04055.21 EKX53514.1 - 5e-18 66.0 0.1 5e-18 66.0 0.1 2.3 3 0 0 3 3 3 1 Radical SAM superfamily UPF0004 PF00919.20 EKX53514.1 - 4.5e-15 55.5 0.0 2.3e-14 53.2 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 TMEM52 PF14979.6 EKX53514.1 - 0.034 14.1 0.6 0.071 13.0 0.6 1.4 1 0 0 1 1 1 0 Transmembrane 52 TRAM PF01938.20 EKX53514.1 - 0.081 12.9 0.2 0.22 11.6 0.2 1.8 1 0 0 1 1 1 0 TRAM domain FliO PF04347.13 EKX53514.1 - 0.1 12.9 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 Flagellar biosynthesis protein, FliO UDPG_MGDP_dh_N PF03721.14 EKX53515.1 - 1.2e-36 126.1 0.0 3.5e-36 124.6 0.0 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 EKX53515.1 - 1.4e-28 99.4 0.0 4.3e-28 97.8 0.0 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 EKX53515.1 - 1.9e-23 82.5 0.0 3.9e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Lipoprotein_11 PF03260.13 EKX53515.1 - 0.14 11.5 0.2 0.21 10.9 0.2 1.2 1 0 0 1 1 1 0 Lepidopteran low molecular weight (30 kD) lipoprotein Catalase-rel PF06628.12 EKX53515.1 - 0.15 12.3 0.1 0.33 11.2 0.1 1.6 1 0 0 1 1 1 0 Catalase-related immune-responsive DOT1 PF08123.13 EKX53516.1 - 2.9e-09 36.7 0.1 4.4e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 IDH PF03971.14 EKX53517.1 - 0 1200.4 0.8 0 1200.2 0.8 1.0 1 0 0 1 1 1 1 Monomeric isocitrate dehydrogenase DUF4115 PF13464.6 EKX53517.1 - 0.13 12.5 0.0 0.8 9.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4115) DUF1018 PF06252.12 EKX53518.1 - 0.044 14.8 2.1 0.06 14.3 1.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1018) Herpes_glycop_H PF02489.16 EKX53518.1 - 0.11 11.0 0.2 0.12 10.8 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein H main domain TSP_C PF05735.12 EKX53518.1 - 0.14 12.1 0.1 0.18 11.7 0.1 1.1 1 0 0 1 1 1 0 Thrombospondin C-terminal region PIN_2 PF10130.9 EKX53519.1 - 0.05 13.8 0.1 0.77 10.0 0.0 2.7 2 0 0 2 2 2 0 PIN domain Brr6_like_C_C PF10104.9 EKX53519.1 - 0.2 11.4 2.0 0.49 10.2 2.0 1.6 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain DUF948 PF06103.11 EKX53519.1 - 0.54 10.5 2.5 10 6.5 0.0 3.8 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) zf-HC5HC2H PF13771.6 EKX53520.1 - 9 6.6 15.3 0.38 11.1 5.0 3.0 1 1 1 2 2 2 0 PHD-like zinc-binding domain Peptidase_C14 PF00656.22 EKX53521.1 - 6.4e-09 36.1 0.0 5.1e-08 33.2 0.0 2.2 2 0 0 2 2 2 1 Caspase domain FKBP_C PF00254.28 EKX53523.1 - 4e-30 104.0 1.1 8e-30 103.0 0.0 2.1 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 EKX53523.1 - 1.4e-05 25.6 0.0 1.4e-05 25.6 0.0 2.6 2 1 0 2 2 2 1 Nucleoplasmin-like domain SAPS PF04499.15 EKX53523.1 - 0.47 9.2 6.9 0.53 9.0 6.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Dicty_REP PF05086.12 EKX53523.1 - 0.61 8.0 11.2 0.75 7.7 11.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CDC45 PF02724.14 EKX53523.1 - 1.3 7.2 14.9 1.9 6.7 14.9 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF4551 PF15087.6 EKX53523.1 - 5.8 5.6 12.0 7.5 5.2 12.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) MCM_bind PF09739.9 EKX53523.1 - 7 5.0 12.9 12 4.2 12.9 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Smg8_Smg9 PF10220.9 EKX53523.1 - 7.2 4.8 12.1 10 4.3 12.1 1.1 1 0 0 1 1 1 0 Smg8_Smg9 Membralin PF09746.9 EKX53523.1 - 9.1 5.2 7.1 14 4.6 7.1 1.2 1 0 0 1 1 1 0 Tumour-associated protein HAD_2 PF13419.6 EKX53524.1 - 2.7e-19 69.9 0.0 6.9e-19 68.6 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EKX53524.1 - 1.8e-12 48.0 0.0 2.9e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EKX53524.1 - 1.1e-08 35.0 0.0 2.5e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Brix PF04427.18 EKX53525.1 - 3.9e-12 46.7 0.4 5.3e-12 46.2 0.4 1.1 1 0 0 1 1 1 1 Brix domain ClpS PF02617.17 EKX53526.1 - 8.1e-18 64.0 0.0 1.2e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS CLIP1_ZNF PF16641.5 EKX53526.1 - 0.16 11.9 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 CLIP1 zinc knuckle DUF4705 PF15788.5 EKX53526.1 - 2.7 8.3 11.3 0.52 10.6 1.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4705) Gp_dh_C PF02800.20 EKX53527.1 - 6.2e-66 220.9 0.0 8.8e-66 220.4 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EKX53527.1 - 1.1e-32 112.4 0.0 2.4e-32 111.3 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EKX53527.1 - 0.097 12.0 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Herpes_US12 PF05363.12 EKX53527.1 - 0.1 13.4 0.0 34 5.2 0.0 2.8 2 1 1 3 3 3 0 Herpesvirus US12 family Laminin_I PF06008.14 EKX53529.1 - 0.03 14.0 1.2 0.041 13.6 1.2 1.2 1 0 0 1 1 1 0 Laminin Domain I APP_E2 PF12925.7 EKX53529.1 - 0.037 13.7 2.5 0.059 13.1 2.5 1.2 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein Arm PF00514.23 EKX53530.1 - 5.3e-13 48.5 0.4 0.015 15.4 0.0 5.8 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat zf-C3HC4_3 PF13920.6 EKX53530.1 - 7.4e-11 41.7 12.5 1.8e-10 40.5 12.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX53530.1 - 8.5e-05 22.3 13.5 0.00017 21.4 13.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EKX53530.1 - 0.00081 19.7 14.0 0.002 18.4 14.0 1.7 1 0 0 1 1 1 1 Ring finger domain HEAT_2 PF13646.6 EKX53530.1 - 0.0021 18.4 0.3 3.8 8.0 0.1 3.1 2 1 2 4 4 4 3 HEAT repeats zf-C3HC4_2 PF13923.6 EKX53530.1 - 0.055 13.3 13.8 0.14 12.0 13.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ndc1_Nup PF09531.10 EKX53530.1 - 0.61 8.7 3.2 4.5 5.8 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DUF3602 PF12223.8 EKX53530.1 - 1.8 9.2 8.9 3.4 8.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) zf-C3HC4_4 PF15227.6 EKX53530.1 - 2.2 8.5 12.1 11 6.3 12.3 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Choline_kinase PF01633.20 EKX53531.1 - 0.0087 15.7 0.0 5.3 6.6 0.0 2.4 2 0 0 2 2 2 2 Choline/ethanolamine kinase SbcD_C PF12320.8 EKX53531.1 - 0.41 11.0 1.7 45 4.4 0.0 2.9 3 0 0 3 3 3 0 Type 5 capsule protein repressor C-terminal domain FAM183 PF14886.6 EKX53532.1 - 4.2e-20 72.5 0.1 5.2e-20 72.2 0.1 1.1 1 0 0 1 1 1 1 FAM183A and FAM183B related LysM PF01476.20 EKX53533.1 - 4.6e-19 68.2 0.0 2e-09 37.4 0.1 2.6 1 1 1 2 2 2 2 LysM domain Imm30 PF15565.6 EKX53534.1 - 0.0049 16.9 3.9 0.0051 16.9 1.1 2.5 2 0 0 2 2 2 1 Immunity protein 30 Tropomyosin_1 PF12718.7 EKX53534.1 - 0.0054 16.9 10.2 0.0054 16.9 10.2 4.2 1 1 1 3 3 3 1 Tropomyosin like FlaC_arch PF05377.11 EKX53534.1 - 0.022 15.2 13.0 2 8.9 0.6 5.2 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) Spc24 PF08286.11 EKX53534.1 - 0.025 14.8 1.6 0.025 14.8 1.6 5.2 2 2 1 3 3 2 0 Spc24 subunit of Ndc80 BRD4_CDT PF17105.5 EKX53534.1 - 0.029 14.0 2.0 0.029 14.0 2.0 2.9 2 0 0 2 2 1 0 C-terminal domain of bromodomain protein 4 Sugarporin_N PF11471.8 EKX53534.1 - 0.029 14.3 3.8 0.029 14.3 3.8 2.6 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension V_ATPase_I PF01496.19 EKX53534.1 - 0.12 10.3 28.2 0.036 12.0 12.9 2.4 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF948 PF06103.11 EKX53534.1 - 1.7 9.0 10.0 5.4 7.3 1.3 4.4 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF2333 PF10095.9 EKX53534.1 - 4.2 6.3 11.4 1.4 7.8 0.5 2.7 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2333) DUF1664 PF07889.12 EKX53534.1 - 4.4 7.4 22.2 0.25 11.4 2.1 4.0 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) Hormone_1 PF00103.20 EKX53534.1 - 9.2 5.9 10.1 0.38 10.5 0.1 3.2 2 2 2 4 4 4 0 Somatotropin hormone family HSP70 PF00012.20 EKX53536.1 - 2.1e-15 56.0 0.0 4.9e-15 54.8 0.0 1.5 1 1 0 1 1 1 1 Hsp70 protein FtsA PF14450.6 EKX53536.1 - 0.13 12.7 0.0 2.1 8.8 0.0 2.4 2 1 0 2 2 2 0 Cell division protein FtsA BTK PF00779.19 EKX53537.1 - 1.5e-05 24.7 4.3 0.00016 21.4 4.3 2.3 1 1 0 1 1 1 1 BTK motif Hairy_orange PF07527.13 EKX53537.1 - 0.00013 22.1 0.2 0.00036 20.7 0.2 1.8 1 0 0 1 1 1 1 Hairy Orange LysM PF01476.20 EKX53537.1 - 0.0028 17.7 0.0 0.0056 16.7 0.0 1.5 1 0 0 1 1 1 1 LysM domain UBA_4 PF14555.6 EKX53537.1 - 0.0088 15.9 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain GAF_2 PF13185.6 EKX53538.1 - 2.2e-32 112.3 0.0 9.8e-10 38.9 0.0 5.8 6 0 0 6 6 6 5 GAF domain GAF PF01590.26 EKX53538.1 - 3e-29 102.3 0.2 9.1e-06 26.3 0.0 6.3 6 0 0 6 6 6 5 GAF domain GAF_3 PF13492.6 EKX53538.1 - 4e-16 59.5 0.0 0.013 15.9 0.0 6.0 6 0 0 6 6 6 4 GAF domain PFK PF00365.20 EKX53540.1 - 5.1e-37 127.7 0.0 9.7e-37 126.8 0.0 1.5 1 1 0 1 1 1 1 Phosphofructokinase DUF2160 PF09928.9 EKX53540.1 - 0.22 11.9 0.3 15 6.0 0.0 2.5 2 0 0 2 2 2 0 Predicted small integral membrane protein (DUF2160) RNA_pol_Rpb2_6 PF00562.28 EKX53541.1 - 6.6e-127 423.8 0.4 9.4e-127 423.3 0.0 1.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EKX53541.1 - 1.4e-49 168.4 0.1 2.1e-49 167.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EKX53541.1 - 2.3e-31 108.1 0.3 4.9e-31 107.0 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 EKX53541.1 - 3.1e-25 88.2 0.5 8e-25 86.9 0.5 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_2 PF04561.14 EKX53541.1 - 9.7e-24 84.0 0.7 2.4e-23 82.8 0.7 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 EKX53541.1 - 1.7e-20 73.0 0.3 4e-20 71.7 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EKX53541.1 - 5.7e-10 39.6 1.0 2.7e-09 37.4 1.0 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RCC1 PF00415.18 EKX53542.1 - 1e-34 118.9 14.4 2e-10 41.2 0.0 6.6 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX53542.1 - 1.9e-33 113.5 7.7 1.1e-08 34.7 0.1 5.7 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat Exo_endo_phos PF03372.23 EKX53542.1 - 0.00011 21.8 0.0 0.00055 19.5 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UL41A PF17591.2 EKX53542.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus UL41A Zn_clus PF00172.18 EKX53543.1 - 2.2e-08 34.1 14.3 3.1e-08 33.6 14.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydrolase PF00702.26 EKX53544.1 - 3.6e-10 40.5 0.0 4.8e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EKX53544.1 - 2.1e-07 31.5 0.0 2.8e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EKX53544.1 - 0.0014 18.0 0.0 0.0019 17.6 0.0 1.1 1 0 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.12 EKX53544.1 - 0.0026 17.3 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) DUF705 PF05152.12 EKX53544.1 - 0.0029 17.1 0.1 0.0044 16.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF705) HAD_2 PF13419.6 EKX53544.1 - 0.026 14.6 0.0 0.039 14.0 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF3437 PF11919.8 EKX53545.1 - 0.058 13.3 0.0 2.5 8.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) HALZ PF02183.18 EKX53546.1 - 0.055 13.7 3.9 0.15 12.3 3.9 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper SO_alpha_A3 PF17806.1 EKX53546.1 - 0.062 13.6 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Sarcosine oxidase A3 domain DUF3074 PF11274.8 EKX53546.1 - 0.1 12.6 3.0 0.12 12.4 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3074) V_ATPase_I PF01496.19 EKX53546.1 - 0.12 10.3 12.9 0.14 10.1 12.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fmp27_WPPW PF10359.9 EKX53546.1 - 0.25 10.2 12.8 0.31 9.8 12.8 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF1043 PF06295.12 EKX53546.1 - 2 8.4 12.1 3 7.9 12.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) FapA PF03961.13 EKX53546.1 - 2.3 6.7 11.5 2.7 6.5 11.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF572 PF04502.13 EKX53546.1 - 7.8 6.0 13.6 9.9 5.7 13.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) ERG2_Sigma1R PF04622.12 EKX53547.1 - 8.8e-85 283.3 0.0 1e-84 283.0 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein DUF3486 PF11985.8 EKX53548.1 - 0.0093 16.4 1.3 0.0093 16.4 1.3 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF3486) Baculo_LEF5_C PF11792.8 EKX53548.1 - 0.094 12.4 1.2 0.26 11.0 1.2 1.7 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain Sgf11 PF08209.11 EKX53548.1 - 0.11 12.0 1.5 0.37 10.4 0.1 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) HALZ PF02183.18 EKX53548.1 - 0.17 12.1 4.1 2.4 8.4 0.1 3.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper Bap31_Bap29_C PF18035.1 EKX53548.1 - 4.9 7.3 6.7 1.2 9.2 0.2 3.2 4 0 0 4 4 4 0 Bap31/Bap29 cytoplasmic coiled-coil domain Mpv17_PMP22 PF04117.12 EKX53549.1 - 1.3e-14 54.1 1.2 3.6e-14 52.7 1.2 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family SET PF00856.28 EKX53550.1 - 1.4e-09 38.6 0.1 3.5e-09 37.3 0.0 1.6 2 0 0 2 2 2 1 SET domain RsgI_N PF12791.7 EKX53550.1 - 0.099 12.6 0.0 0.25 11.3 0.0 1.6 2 0 0 2 2 2 0 Anti-sigma factor N-terminus SLED PF12140.8 EKX53550.1 - 0.13 12.8 0.0 0.22 12.1 0.0 1.3 1 0 0 1 1 1 0 SLED domain CRAL_TRIO PF00650.20 EKX53551.1 - 3.4e-14 52.9 0.3 1.6e-13 50.7 0.1 2.0 2 0 0 2 2 2 1 CRAL/TRIO domain GOLD_2 PF13897.6 EKX53551.1 - 0.036 14.5 0.0 0.092 13.2 0.0 1.6 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking UFD1 PF03152.14 EKX53554.1 - 6.9e-34 116.8 0.0 4.9e-19 68.4 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 UBX PF00789.20 EKX53554.1 - 3.8e-09 36.6 0.0 1.7e-08 34.6 0.0 2.1 2 0 0 2 2 2 1 UBX domain DUF719 PF05334.13 EKX53554.1 - 0.0032 17.7 0.1 0.0032 17.7 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF719) YL1 PF05764.13 EKX53554.1 - 0.0093 16.1 1.9 0.0093 16.1 1.9 2.2 2 0 0 2 2 2 1 YL1 nuclear protein CDC48_2 PF02933.17 EKX53554.1 - 0.054 13.3 0.5 0.1 12.4 0.5 1.4 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 LicD PF04991.13 EKX53554.1 - 0.91 9.6 7.2 3.5 7.7 0.0 2.2 2 0 0 2 2 2 0 LicD family OmpH PF03938.14 EKX53554.1 - 1.7 9.0 26.7 0.13 12.6 15.0 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF87 PF01935.17 EKX53554.1 - 9.1 6.3 8.8 11 6.0 0.4 2.5 3 0 0 3 3 3 0 Helicase HerA, central domain DUF4064 PF13273.6 EKX53555.1 - 0.00053 20.2 4.3 0.0047 17.2 4.4 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF4064) CD20 PF04103.15 EKX53555.1 - 0.0091 16.1 3.6 0.031 14.4 0.7 2.1 1 1 1 2 2 2 1 CD20-like family DUF1129 PF06570.11 EKX53555.1 - 0.067 12.7 0.7 0.091 12.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Thioredoxin PF00085.20 EKX53556.1 - 6.8e-21 74.2 0.0 7.1e-21 74.1 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EKX53556.1 - 0.00046 20.5 0.0 0.033 14.5 0.0 2.0 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_3 PF13192.6 EKX53556.1 - 0.013 15.5 0.0 0.014 15.5 0.0 1.0 1 0 0 1 1 1 0 Thioredoxin domain TraF PF13728.6 EKX53556.1 - 0.016 15.0 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 EKX53556.1 - 0.025 15.0 0.1 0.15 12.6 0.1 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain OST3_OST6 PF04756.13 EKX53556.1 - 0.027 13.8 0.0 0.029 13.7 0.0 1.0 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EKX53556.1 - 0.058 13.3 0.0 0.064 13.2 0.0 1.1 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_9 PF14595.6 EKX53556.1 - 0.062 13.1 0.0 0.062 13.1 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Glutaredoxin PF00462.24 EKX53556.1 - 0.1 12.8 0.6 0.2 11.9 0.6 1.6 1 1 0 1 1 1 0 Glutaredoxin DUF2859 PF11072.8 EKX53556.1 - 0.13 12.0 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) Ank_4 PF13637.6 EKX53557.1 - 8e-18 64.6 0.1 1.3e-09 38.4 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX53557.1 - 6.5e-15 55.5 0.0 8.1e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX53557.1 - 1.1e-14 54.3 0.0 5.3e-11 42.5 0.1 2.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX53557.1 - 1.4e-11 44.3 0.2 3.3e-06 27.3 0.2 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EKX53557.1 - 2.9e-10 39.5 0.2 0.00013 22.1 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat HECT PF00632.25 EKX53558.1 - 3.4e-72 243.5 0.0 4e-72 243.3 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Alpha_kinase PF02816.18 EKX53559.1 - 4.3e-08 33.5 0.7 9.8e-08 32.3 0.7 1.5 1 1 0 1 1 1 1 Alpha-kinase family LcrG PF07216.12 EKX53559.1 - 0.014 15.3 2.2 0.022 14.7 2.2 1.3 1 0 0 1 1 1 0 LcrG protein SRRM_C PF15230.6 EKX53559.1 - 0.047 14.2 11.3 0.092 13.3 11.3 1.5 1 0 0 1 1 1 0 Serine/arginine repetitive matrix protein C-terminus Hydin_ADK PF17213.3 EKX53559.1 - 2.1 8.6 5.6 3.7 7.8 5.6 1.3 1 1 0 1 1 1 0 Hydin Adenylate kinase-like domain Say1_Mug180 PF10340.9 EKX53560.1 - 0.025 13.4 0.4 0.03 13.2 0.4 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase KIP1 PF07765.12 EKX53560.1 - 0.028 14.6 5.5 0.18 11.9 5.1 2.3 1 1 0 1 1 1 0 KIP1-like protein Prominin PF05478.11 EKX53560.1 - 0.064 11.2 1.7 0.073 11.0 1.7 1.0 1 0 0 1 1 1 0 Prominin RRF_GI PF12614.8 EKX53560.1 - 0.11 12.6 3.8 0.14 12.3 3.0 1.6 1 1 0 1 1 1 0 Ribosome recycling factor Baculo_p24 PF05073.12 EKX53560.1 - 0.14 11.9 2.3 0.19 11.5 2.3 1.1 1 0 0 1 1 1 0 Baculovirus P24 capsid protein Fib_alpha PF08702.10 EKX53560.1 - 2.5 8.3 7.0 5.1 7.3 6.9 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Ins145_P3_rec PF08709.11 EKX53561.1 - 9.8e-29 100.1 0.1 1.6e-26 92.9 0.4 3.1 2 2 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RIH_assoc PF08454.11 EKX53561.1 - 3.1e-22 78.3 2.6 2.2e-21 75.6 0.2 3.8 3 0 0 3 3 3 1 RyR and IP3R Homology associated RYDR_ITPR PF01365.21 EKX53561.1 - 1.9e-12 47.0 7.7 2.3e-05 23.9 2.5 3.9 3 0 0 3 3 3 2 RIH domain Ion_trans PF00520.31 EKX53561.1 - 5.4e-11 42.2 11.9 1.5e-10 40.7 11.9 1.8 1 0 0 1 1 1 1 Ion transport protein MIR PF02815.19 EKX53561.1 - 3e-10 40.3 0.1 3.7e-07 30.2 0.0 2.9 2 0 0 2 2 2 2 MIR domain CRCB PF02537.15 EKX53562.1 - 0.00059 20.1 2.9 0.00086 19.6 2.8 1.4 1 1 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) WCOR413 PF05562.11 EKX53562.1 - 0.052 13.5 0.2 0.056 13.4 0.2 1.1 1 0 0 1 1 1 0 Cold acclimation protein WCOR413 DUF3336 PF11815.8 EKX53563.1 - 5.4e-36 123.4 0.1 6.2e-35 119.9 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EKX53563.1 - 1.6e-25 90.5 0.0 3.2e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase MMR_HSR1 PF01926.23 EKX53564.1 - 3.3e-07 30.4 0.0 4.7e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EKX53564.1 - 0.00043 20.2 0.0 0.0038 17.1 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 EKX53564.1 - 0.00053 20.5 0.7 0.0016 19.0 0.3 2.0 2 1 0 2 2 2 1 ABC transporter AIG1 PF04548.16 EKX53564.1 - 0.0033 16.8 0.0 0.018 14.4 0.0 1.9 2 0 0 2 2 2 1 AIG1 family AAA_29 PF13555.6 EKX53564.1 - 0.031 14.0 0.1 0.086 12.6 0.1 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 EKX53564.1 - 0.056 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_7 PF12775.7 EKX53564.1 - 0.067 12.7 0.4 0.28 10.7 0.1 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 EKX53564.1 - 0.077 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 EKX53564.1 - 0.093 12.7 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_10 PF12846.7 EKX53564.1 - 0.13 11.1 0.2 0.21 10.5 0.2 1.2 1 0 0 1 1 1 0 AAA-like domain Dynamin_N PF00350.23 EKX53564.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Dynamin family Ferric_reduct PF01794.19 EKX53565.1 - 1.9 8.6 15.7 0.69 10.0 11.6 2.5 2 1 0 2 2 2 0 Ferric reductase like transmembrane component PLA2_B PF01735.18 EKX53566.1 - 8.7e-11 40.9 0.1 3.4e-07 29.1 0.0 3.0 2 1 0 2 2 2 2 Lysophospholipase catalytic domain Glyco_transf_49 PF13896.6 EKX53567.1 - 1e-39 136.8 2.3 4e-20 72.4 0.0 3.2 1 1 2 3 3 3 3 Glycosyl-transferase for dystroglycan DUF2013 PF09431.10 EKX53568.1 - 0.0034 17.6 3.0 0.0074 16.5 2.6 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF2013) SPO22 PF08631.10 EKX53568.1 - 0.12 11.8 2.6 0.17 11.3 2.6 1.2 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like LRR_8 PF13855.6 EKX53569.1 - 1.8e-203 658.6 178.4 9.4e-17 60.5 1.0 16.9 1 1 17 18 18 18 18 Leucine rich repeat LRR_4 PF12799.7 EKX53569.1 - 1.3e-87 286.1 79.6 1.3e-06 28.7 0.2 17.0 14 2 3 17 17 17 17 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 EKX53569.1 - 4.2e-82 272.5 0.0 1.5e-11 44.3 0.0 8.3 1 1 9 10 10 10 10 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EKX53569.1 - 1e-32 107.6 110.5 0.05 14.2 0.1 30.1 31 1 0 31 31 31 13 Leucine Rich Repeat LRR_9 PF14580.6 EKX53569.1 - 2.1e-20 73.0 0.1 0.15 11.6 0.0 8.6 1 1 7 10 10 10 6 Leucine-rich repeat DER1 PF04511.15 EKX53569.1 - 2e-07 31.1 17.5 8.6 6.2 0.0 11.0 2 2 12 14 14 14 2 Der1-like family HTH_19 PF12844.7 EKX53569.1 - 9.1e-07 28.8 6.7 43 4.2 0.0 10.8 11 3 2 13 13 13 0 Helix-turn-helix domain TPR_12 PF13424.6 EKX53570.1 - 2.6e-11 43.6 8.7 8.4e-11 42.0 0.5 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat NACHT PF05729.12 EKX53570.1 - 3.6e-08 33.5 0.1 8.3e-08 32.3 0.1 1.6 1 0 0 1 1 1 1 NACHT domain TPR_10 PF13374.6 EKX53570.1 - 1e-06 28.4 6.6 0.0014 18.4 0.1 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat AAA_16 PF13191.6 EKX53570.1 - 2.8e-06 27.8 1.7 9.1e-06 26.2 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain TPR_16 PF13432.6 EKX53570.1 - 2.5e-05 24.8 0.4 0.00017 22.2 0.4 2.6 1 0 0 1 1 1 1 Tetratricopeptide repeat NB-ARC PF00931.22 EKX53570.1 - 3e-05 23.3 0.0 0.0001 21.6 0.0 1.9 1 0 0 1 1 1 1 NB-ARC domain IQ PF00612.27 EKX53570.1 - 5e-05 22.7 1.7 0.035 13.9 0.1 3.0 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.6 EKX53570.1 - 0.00012 22.3 0.0 0.00061 20.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain TPR_1 PF00515.28 EKX53570.1 - 0.0039 16.9 3.3 0.048 13.5 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat DUF4062 PF13271.6 EKX53570.1 - 0.0072 16.7 1.5 0.035 14.5 0.0 3.0 3 0 0 3 3 2 1 Domain of unknown function (DUF4062) TPR_8 PF13181.6 EKX53570.1 - 0.011 15.9 4.8 4 7.9 0.0 4.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EKX53570.1 - 0.015 15.4 0.1 0.015 15.4 0.1 5.0 6 0 0 6 6 4 0 Tetratricopeptide repeat AAA PF00004.29 EKX53570.1 - 0.032 14.6 0.0 0.18 12.2 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPR_19 PF14559.6 EKX53570.1 - 0.035 14.6 5.8 0.15 12.6 0.1 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat AAA_18 PF13238.6 EKX53570.1 - 0.063 13.8 0.0 0.46 11.0 0.0 2.6 2 0 0 2 2 1 0 AAA domain Roc PF08477.13 EKX53570.1 - 0.063 13.5 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 EKX53570.1 - 0.13 11.7 0.0 1.9 7.9 0.0 2.4 2 1 1 3 3 3 0 P-loop containing dynein motor region cobW PF02492.19 EKX53570.1 - 0.14 11.7 0.1 0.43 10.1 0.1 1.8 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TPR_7 PF13176.6 EKX53570.1 - 0.5 10.5 4.1 2.7 8.2 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat LMP PF04778.12 EKX53570.1 - 0.66 9.9 8.1 1.7 8.5 0.9 3.8 4 0 0 4 4 3 0 LMP repeated region TPR_4 PF07721.14 EKX53570.1 - 2.9 8.8 10.8 0.2 12.4 3.1 3.4 4 0 0 4 4 1 0 Tetratricopeptide repeat ABC_tran PF00005.27 EKX53570.1 - 5.7 7.5 5.8 1.8 9.1 0.0 3.2 3 1 0 3 3 2 0 ABC transporter TPR_14 PF13428.6 EKX53570.1 - 8.1 7.6 11.7 1.4 9.9 0.5 5.2 5 0 0 5 5 3 0 Tetratricopeptide repeat LLC1 PF14945.6 EKX53571.1 - 0.0026 18.3 0.3 0.0031 18.1 0.3 1.2 1 1 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein PknH_C PF14032.6 EKX53571.1 - 0.017 15.0 0.1 0.02 14.8 0.1 1.1 1 0 0 1 1 1 0 PknH-like extracellular domain FAM110_N PF14161.6 EKX53571.1 - 0.2 11.9 1.2 0.29 11.4 1.2 1.7 1 1 0 1 1 1 0 Centrosome-associated N terminus He_PIG PF05345.12 EKX53572.1 - 5e-07 29.8 0.4 2.3e-05 24.5 0.1 2.4 2 0 0 2 2 2 2 Putative Ig domain MFS_1 PF07690.16 EKX53574.1 - 2.5e-34 118.8 27.9 3.5e-34 118.3 27.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EKX53574.1 - 0.58 8.9 28.2 0.014 14.3 5.2 3.1 1 1 1 3 3 3 0 Sugar (and other) transporter Exo_endo_phos PF03372.23 EKX53575.1 - 1.4e-11 44.3 0.0 3.6e-11 43.0 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_U57 PF05582.12 EKX53575.1 - 1.8 7.8 9.2 3.4 6.9 9.2 1.4 1 0 0 1 1 1 0 YabG peptidase U57 SID-1_RNA_chan PF13965.6 EKX53575.1 - 8.9 4.6 6.1 13 4.0 6.1 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 zf-met PF12874.7 EKX53576.1 - 0.00066 20.0 0.1 0.0019 18.5 0.1 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EKX53576.1 - 0.0018 18.2 0.1 0.0038 17.2 0.1 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EKX53576.1 - 0.0064 16.7 0.3 0.018 15.3 0.0 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EKX53576.1 - 0.069 14.0 0.7 0.45 11.5 0.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger ABC_membrane PF00664.23 EKX53577.1 - 6.1e-113 377.0 28.9 1.2e-63 215.4 6.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EKX53577.1 - 1.1e-72 242.9 0.1 1.4e-36 126.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EKX53577.1 - 9.3e-15 54.7 6.6 8.5e-06 25.4 0.1 4.2 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EKX53577.1 - 4.5e-09 36.7 0.1 0.0049 17.2 0.0 3.3 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EKX53577.1 - 7.6e-09 35.2 0.5 0.0024 17.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EKX53577.1 - 7.2e-08 33.0 4.0 0.0047 17.3 0.2 3.3 3 2 0 3 3 2 2 AAA ATPase domain ABC_ATPase PF09818.9 EKX53577.1 - 2.1e-07 30.1 1.2 0.044 12.6 0.0 3.7 3 1 1 4 4 4 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 EKX53577.1 - 2.9e-07 30.5 0.0 0.03 14.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 EKX53577.1 - 3e-07 29.9 1.5 0.012 15.0 0.0 3.2 4 0 0 4 4 3 2 Zeta toxin AAA_30 PF13604.6 EKX53577.1 - 4.8e-06 26.4 1.0 0.097 12.4 0.1 3.4 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.6 EKX53577.1 - 5e-06 26.5 0.0 0.05 13.4 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 EKX53577.1 - 1.9e-05 24.2 0.0 0.27 10.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF87 PF01935.17 EKX53577.1 - 2.9e-05 24.3 0.1 0.37 10.9 0.0 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_15 PF13175.6 EKX53577.1 - 3.2e-05 23.8 0.0 0.1 12.3 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 EKX53577.1 - 9.2e-05 22.9 1.9 1.7 9.1 0.0 4.2 3 2 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EKX53577.1 - 0.0001 22.3 0.1 0.56 10.2 0.0 3.7 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 EKX53577.1 - 0.00016 21.6 0.3 0.17 11.8 0.1 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase G-alpha PF00503.20 EKX53577.1 - 0.00019 20.7 0.0 0.12 11.5 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit DUF815 PF05673.13 EKX53577.1 - 0.00025 20.3 0.2 2.7 7.1 0.0 3.2 2 1 0 3 3 3 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 EKX53577.1 - 0.00037 20.8 0.0 12 6.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 EKX53577.1 - 0.00037 20.1 0.0 0.74 9.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 EKX53577.1 - 0.00052 20.2 2.8 1.2 9.4 0.1 4.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 EKX53577.1 - 0.0008 19.5 0.2 2.4 8.3 0.0 3.2 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_33 PF13671.6 EKX53577.1 - 0.0017 18.5 0.0 1.6 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 EKX53577.1 - 0.0018 18.0 0.0 2 8.0 0.0 2.8 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 EKX53577.1 - 0.005 17.4 0.0 2.7 8.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EKX53577.1 - 0.0051 16.6 0.0 3.4 7.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 EKX53577.1 - 0.012 14.9 0.0 1.6 8.0 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Mg_chelatase PF01078.21 EKX53577.1 - 0.037 13.4 0.0 6.7 6.0 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SRP54 PF00448.22 EKX53577.1 - 0.043 13.4 0.1 9.3 5.8 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 EKX53577.1 - 0.054 14.0 2.9 3.6 8.1 0.4 2.4 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 EKX53577.1 - 0.07 12.9 0.0 9.4 5.9 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NTPase_1 PF03266.15 EKX53577.1 - 0.075 12.9 2.0 52 3.7 0.0 4.1 3 1 1 4 4 4 0 NTPase DUF2520 PF10728.9 EKX53577.1 - 0.12 12.1 0.0 13 5.5 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2520) NB-ARC PF00931.22 EKX53577.1 - 0.15 11.2 0.1 4.9 6.3 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_19 PF13245.6 EKX53577.1 - 0.15 12.4 0.2 38 4.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain ABC_membrane PF00664.23 EKX53578.1 - 3.2e-108 361.5 23.7 5.1e-63 213.3 4.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EKX53578.1 - 2.6e-72 241.7 0.1 2.7e-36 125.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EKX53578.1 - 2.8e-14 53.1 7.1 1.3e-05 24.7 0.1 4.2 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EKX53578.1 - 9.4e-09 34.9 0.5 0.0027 17.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EKX53578.1 - 2.7e-08 34.2 0.2 0.02 15.2 0.0 3.2 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EKX53578.1 - 3.2e-08 34.1 2.5 0.0052 17.2 0.2 3.2 3 1 0 3 3 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EKX53578.1 - 3.9e-07 30.1 0.0 0.033 14.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 EKX53578.1 - 4e-07 29.5 1.6 0.013 14.8 0.0 3.1 4 0 0 4 4 3 2 Zeta toxin ABC_ATPase PF09818.9 EKX53578.1 - 5.4e-07 28.8 1.5 0.068 12.0 0.0 3.6 3 1 1 4 4 4 2 Predicted ATPase of the ABC class AAA_21 PF13304.6 EKX53578.1 - 6.5e-06 26.2 0.1 0.056 13.2 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EKX53578.1 - 7.5e-06 25.8 1.2 0.11 12.2 0.1 3.4 2 2 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EKX53578.1 - 1.2e-05 24.9 0.0 0.3 10.6 0.0 3.0 3 0 0 3 3 3 2 P-loop containing dynein motor region DUF87 PF01935.17 EKX53578.1 - 3.8e-05 23.9 0.1 0.41 10.7 0.0 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_15 PF13175.6 EKX53578.1 - 4e-05 23.5 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 EKX53578.1 - 7.7e-05 23.1 0.5 1.9 8.9 0.0 3.8 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EKX53578.1 - 0.00014 21.9 0.1 0.63 10.0 0.0 3.7 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 EKX53578.1 - 0.0002 21.3 0.3 0.19 11.6 0.1 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase G-alpha PF00503.20 EKX53578.1 - 0.00024 20.4 0.0 0.14 11.3 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_28 PF13521.6 EKX53578.1 - 0.00027 21.2 0.0 12 6.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.13 EKX53578.1 - 0.00033 19.9 0.2 2.7 7.1 0.0 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 EKX53578.1 - 0.00044 19.9 0.0 0.86 9.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EKX53578.1 - 0.0011 19.1 0.3 2.6 8.1 0.0 3.2 3 0 0 3 3 2 2 50S ribosome-binding GTPase SbcCD_C PF13558.6 EKX53578.1 - 0.0013 18.9 3.3 1.7 9.0 0.2 4.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 EKX53578.1 - 0.0022 18.2 0.0 1.8 8.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 EKX53578.1 - 0.0041 16.8 0.0 2.3 7.8 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.6 EKX53578.1 - 0.0064 16.2 0.0 3.8 7.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EKX53578.1 - 0.0065 17.0 0.0 3 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 EKX53578.1 - 0.017 14.5 0.0 1.8 7.9 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family SRP54 PF00448.22 EKX53578.1 - 0.045 13.4 0.1 10 5.7 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Mg_chelatase PF01078.21 EKX53578.1 - 0.047 13.1 0.0 7.5 5.9 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 EKX53578.1 - 0.07 13.6 2.9 3.9 7.9 0.4 2.4 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 EKX53578.1 - 0.081 12.7 0.0 10 5.8 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 EKX53578.1 - 0.19 10.9 0.1 5.4 6.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 EKX53578.1 - 0.2 11.6 2.4 58 3.6 0.0 4.0 3 1 1 4 4 4 0 NTPase ABC_membrane PF00664.23 EKX53579.1 - 3.4e-97 325.4 23.8 2.9e-51 174.7 6.8 2.8 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EKX53579.1 - 3.1e-58 196.1 0.0 6.3e-33 114.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EKX53579.1 - 9.5e-09 35.0 3.5 0.00034 20.1 0.0 4.3 3 1 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EKX53579.1 - 2.5e-08 33.6 0.6 0.0074 16.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EKX53579.1 - 9.5e-07 28.9 0.0 0.061 13.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EKX53579.1 - 1.1e-06 29.1 0.3 0.0053 17.2 0.2 3.0 2 1 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 EKX53579.1 - 1.6e-06 27.6 0.7 0.1 11.9 0.0 3.7 4 0 0 4 4 4 2 Zeta toxin AAA_21 PF13304.6 EKX53579.1 - 3.1e-06 27.2 0.2 0.058 13.2 0.0 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EKX53579.1 - 1.4e-05 25.4 0.2 0.021 15.1 0.0 3.3 2 2 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EKX53579.1 - 4e-05 23.4 0.2 0.47 10.2 0.1 3.0 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EKX53579.1 - 8.2e-05 22.2 0.0 0.32 10.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_15 PF13175.6 EKX53579.1 - 8.8e-05 22.4 0.0 0.24 11.1 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 EKX53579.1 - 0.00022 20.9 0.2 0.89 9.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 EKX53579.1 - 0.00029 19.8 0.1 0.07 11.9 0.0 3.3 2 1 1 3 3 3 1 Predicted ATPase of the ABC class ATP-synt_ab PF00006.25 EKX53579.1 - 0.00035 20.3 0.1 0.5 10.0 0.0 2.5 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.17 EKX53579.1 - 0.00071 19.7 0.1 0.42 10.7 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_24 PF13479.6 EKX53579.1 - 0.00096 18.9 0.0 0.43 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 EKX53579.1 - 0.0016 17.6 0.1 2.8 7.0 0.0 3.3 2 1 1 3 3 3 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EKX53579.1 - 0.0019 18.2 0.0 0.65 10.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 EKX53579.1 - 0.003 17.5 0.3 2.9 7.8 0.1 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase G-alpha PF00503.20 EKX53579.1 - 0.0036 16.5 0.0 2.1 7.4 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 EKX53579.1 - 0.009 16.1 0.2 2.7 8.1 0.0 3.1 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 EKX53579.1 - 0.016 15.7 0.4 3.1 8.4 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EKX53579.1 - 0.024 14.8 0.0 1.8 8.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EKX53579.1 - 0.033 14.6 0.3 23 5.4 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 EKX53579.1 - 0.042 14.1 0.0 14 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EKX53579.1 - 0.046 13.1 0.0 1.9 7.8 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 EKX53579.1 - 0.05 14.1 1.6 6.2 7.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 EKX53579.1 - 0.057 13.1 0.0 22 4.6 0.0 3.4 3 0 0 3 3 3 0 Thymidylate kinase AAA_19 PF13245.6 EKX53579.1 - 0.097 13.0 0.6 15 5.9 0.0 2.7 3 0 0 3 3 2 0 AAA domain SbcCD_C PF13558.6 EKX53579.1 - 0.26 11.5 1.1 7.2 6.9 0.3 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit LigB PF02900.18 EKX53580.1 - 1.4e-25 89.9 0.0 1.7e-25 89.6 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase GSCFA PF08885.11 EKX53581.1 - 6.6e-81 271.4 0.1 9.1e-81 271.0 0.1 1.2 1 0 0 1 1 1 1 GSCFA family Lipase_GDSL_2 PF13472.6 EKX53581.1 - 0.035 14.5 0.0 0.053 13.9 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family SET PF00856.28 EKX53582.1 - 1.5e-16 61.2 0.0 3.2e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 SET domain SAF PF08666.12 EKX53582.1 - 0.042 14.5 0.3 12 6.6 0.0 2.8 3 0 0 3 3 3 0 SAF domain Lactamase_B_4 PF13691.6 EKX53583.1 - 1.1e-07 31.4 0.0 4.9e-07 29.3 0.0 2.2 1 1 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 EKX53583.1 - 3.4e-06 27.2 0.0 6.5e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EKX53583.1 - 0.00031 20.3 0.0 0.00068 19.2 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain zf-C2H2 PF00096.26 EKX53583.1 - 0.0013 19.1 0.2 0.005 17.2 0.2 2.1 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EKX53583.1 - 0.003 18.3 0.4 0.012 16.4 0.4 2.2 1 0 0 1 1 1 1 C2H2-type zinc finger zf-met PF12874.7 EKX53583.1 - 0.0079 16.6 0.2 0.021 15.2 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Lactamase_B_6 PF16661.5 EKX53583.1 - 0.027 13.9 0.0 0.061 12.8 0.0 1.6 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily domain zf-C2H2_3rep PF18868.1 EKX53583.1 - 0.047 14.4 0.1 0.15 12.7 0.1 1.8 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 EKX53583.1 - 0.093 12.8 0.2 0.18 11.8 0.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger Methyltransf_25 PF13649.6 EKX53584.1 - 1.5e-12 48.1 0.1 1.1e-11 45.3 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX53584.1 - 2e-12 47.2 2.1 6.9e-12 45.5 2.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX53584.1 - 1.2e-11 45.1 0.1 2.7e-10 40.8 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX53584.1 - 4.2e-11 43.5 0.0 1.9e-10 41.3 0.0 2.1 3 0 0 3 3 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX53584.1 - 1.3e-06 27.9 0.0 2.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EKX53584.1 - 3.4e-06 26.9 0.0 5.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EKX53584.1 - 6.2e-05 22.1 0.0 9.1e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 EKX53584.1 - 0.0021 17.4 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NNMT_PNMT_TEMT PF01234.17 EKX53584.1 - 0.0045 16.2 0.0 1.1 8.4 0.0 2.2 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family Pox_MCEL PF03291.16 EKX53584.1 - 0.0092 15.1 0.0 0.012 14.7 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme MTS PF05175.14 EKX53584.1 - 0.0099 15.4 0.0 0.03 13.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 EKX53584.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.6 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 EKX53584.1 - 0.039 13.6 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Rsm22 PF09243.10 EKX53584.1 - 0.04 13.2 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_PK PF05891.12 EKX53584.1 - 0.07 12.6 0.0 0.13 11.7 0.0 1.4 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.7 EKX53584.1 - 0.086 12.8 0.0 0.36 10.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Zip PF02535.22 EKX53584.1 - 5 6.2 11.2 8.2 5.5 11.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter His_Phos_2 PF00328.22 EKX53585.1 - 4.7e-26 92.0 0.1 8.3e-23 81.4 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) DnaJ PF00226.31 EKX53586.1 - 2.3e-16 59.7 0.3 4.6e-16 58.7 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain TPR_16 PF13432.6 EKX53586.1 - 4.6e-10 40.0 3.3 1.5e-06 28.8 1.9 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX53586.1 - 7.2e-06 25.7 4.0 0.41 10.9 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX53586.1 - 0.0092 15.6 0.1 5.9 6.7 0.0 2.6 2 0 0 2 2 2 2 TPR repeat CVNH PF08881.10 EKX53586.1 - 0.0096 16.6 0.1 0.025 15.2 0.1 1.7 1 0 0 1 1 1 1 CVNH domain TPR_7 PF13176.6 EKX53586.1 - 0.033 14.2 0.1 6 7.1 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX53586.1 - 0.065 14.1 5.8 4.8 8.3 0.7 3.7 1 1 2 3 3 3 0 Tetratricopeptide repeat Cytochrome_C7 PF14522.6 EKX53586.1 - 0.11 12.5 1.4 1.3 9.0 0.0 2.5 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c eIF-5a PF01287.20 EKX53586.1 - 0.15 12.2 0.1 0.41 10.8 0.1 1.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold PDZ PF00595.24 EKX53587.1 - 2.6e-09 37.3 0.2 4.2e-09 36.6 0.2 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX53587.1 - 5.1e-05 23.0 0.4 0.0001 22.0 0.4 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX53587.1 - 0.00052 20.3 0.2 0.00095 19.4 0.2 1.4 1 0 0 1 1 1 1 PDZ domain NRDE-2 PF08424.10 EKX53588.1 - 9.7e-62 208.9 29.5 6.2e-35 120.9 17.8 4.3 2 1 1 3 3 3 3 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 EKX53588.1 - 1.2e-06 28.8 4.6 0.015 16.0 0.0 5.7 4 1 1 5 5 5 2 Tetratricopeptide repeat DMRL_synthase PF00885.19 EKX53588.1 - 0.061 13.1 1.8 1.9 8.3 0.1 2.4 2 0 0 2 2 2 0 6,7-dimethyl-8-ribityllumazine synthase TPR_19 PF14559.6 EKX53588.1 - 0.11 13.0 0.0 5 7.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Spem1 PF15670.5 EKX53588.1 - 3.1 7.3 9.6 1.1 8.7 6.0 2.1 2 0 0 2 2 2 0 Spermatid maturation protein 1 Phtf-FEM1B_bdg PF12129.8 EKX53590.1 - 3.6 7.4 5.2 0.6 9.9 0.6 2.0 2 0 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor OSCP PF00213.18 EKX53591.1 - 2e-38 132.2 0.0 2.4e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit MCR_D PF02505.14 EKX53591.1 - 0.017 15.0 0.4 2.9 7.7 0.2 2.5 2 1 0 2 2 2 0 Methyl-coenzyme M reductase operon protein D Mt_ATP-synt_D PF05873.12 EKX53592.1 - 9.6e-12 45.0 2.7 1.4e-11 44.5 2.7 1.2 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) ApoLp-III PF07464.11 EKX53592.1 - 0.004 17.3 2.2 1.3 9.1 1.7 2.4 2 1 0 2 2 2 2 Apolipophorin-III precursor (apoLp-III) M PF02370.16 EKX53592.1 - 0.031 14.8 1.6 0.17 12.5 1.6 2.3 1 0 0 1 1 1 0 M protein repeat FliT PF05400.13 EKX53592.1 - 0.058 14.2 6.6 0.067 14.0 0.7 2.6 3 0 0 3 3 3 0 Flagellar protein FliT TRCF PF03461.15 EKX53592.1 - 0.073 13.5 0.3 1.1 9.6 0.3 2.2 2 0 0 2 2 2 0 TRCF domain Fzo_mitofusin PF04799.13 EKX53592.1 - 0.092 12.3 1.1 0.19 11.3 1.1 1.5 1 0 0 1 1 1 0 fzo-like conserved region T3SS_needle_F PF09392.10 EKX53592.1 - 0.37 11.0 1.7 4.2 7.6 0.4 2.6 2 0 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF CLZ PF16526.5 EKX53592.1 - 0.56 10.6 4.8 6.3 7.2 3.0 3.2 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels OmpH PF03938.14 EKX53592.1 - 4.2 7.7 12.9 0.67 10.3 7.5 2.2 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) BMFP PF04380.13 EKX53592.1 - 6.9 7.2 10.5 7.4 7.1 4.0 3.6 4 0 0 4 4 4 0 Membrane fusogenic activity DUF5323 PF17257.2 EKX53593.1 - 6.1e-07 29.2 2.9 8.6e-07 28.7 2.9 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5323) Adaptin_N PF01602.20 EKX53595.1 - 4.1e-09 35.5 0.6 5.7e-09 35.1 0.6 1.2 1 1 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.22 EKX53595.1 - 5.1e-09 35.6 3.3 0.0003 20.8 0.1 4.3 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 EKX53595.1 - 5.6e-09 36.3 1.3 1.6e-05 25.2 0.1 3.0 1 1 2 3 3 3 3 HEAT repeats Cnd1 PF12717.7 EKX53595.1 - 6.8e-06 26.2 0.8 6.4e-05 23.0 0.5 2.4 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 EKX53595.1 - 0.0026 18.0 0.8 0.027 14.8 0.2 2.7 2 1 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Nipped-B_C PF12830.7 EKX53595.1 - 0.0072 16.3 1.1 0.14 12.1 0.4 2.2 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus RTP1_C1 PF10363.9 EKX53595.1 - 0.021 15.0 0.0 0.23 11.6 0.0 2.1 1 1 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 RB_A PF01858.17 EKX53595.1 - 0.029 14.2 0.2 0.041 13.7 0.2 1.3 1 0 0 1 1 1 0 Retinoblastoma-associated protein A domain CLASP_N PF12348.8 EKX53595.1 - 0.056 13.0 0.1 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 CLASP N terminal DUF4042 PF13251.6 EKX53595.1 - 0.092 12.4 0.1 0.53 10.0 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4042) DUF2437 PF10370.9 EKX53596.1 - 0.5 11.3 0.1 0.5 11.3 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF2437) DNA_pol_phi PF04931.13 EKX53596.1 - 7.8 4.5 5.6 7.8 4.5 5.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF1704 PF08014.11 EKX53597.1 - 0.00052 19.1 0.1 0.0041 16.2 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1704) HTH_Tnp_Mu_1 PF02316.16 EKX53597.1 - 0.027 14.6 0.0 0.089 13.0 0.0 1.8 1 0 0 1 1 1 0 Mu DNA-binding domain PseudoU_synth_1 PF01416.20 EKX53598.1 - 7.3e-06 26.4 0.6 0.081 13.4 0.1 2.6 3 0 0 3 3 3 2 tRNA pseudouridine synthase DUF2344 PF10105.9 EKX53598.1 - 0.04 13.8 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) eIF-3_zeta PF05091.12 EKX53599.1 - 1.1e-148 496.5 0.4 1.3e-148 496.3 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 EKX53599.1 - 0.0048 16.4 0.0 0.0079 15.7 0.0 1.3 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus Pyridoxal_deC PF00282.19 EKX53600.1 - 1.6e-22 79.8 0.0 2.9e-22 78.9 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EKX53600.1 - 0.00014 20.9 0.0 0.00019 20.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EKX53600.1 - 0.11 11.8 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase TrkH PF02386.16 EKX53601.1 - 3.7e-57 193.9 11.9 2e-54 184.9 8.2 2.1 2 0 0 2 2 2 2 Cation transport protein DUF2417 PF10329.9 EKX53601.1 - 0.023 14.1 2.9 0.96 8.8 0.0 2.6 2 0 0 2 2 2 0 Region of unknown function (DUF2417) Bromodomain PF00439.25 EKX53602.1 - 3.5e-22 78.3 0.3 6.2e-22 77.5 0.3 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 EKX53602.1 - 1.3e-10 41.5 0.1 2.8e-10 40.5 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EKX53602.1 - 3.3e-09 36.8 0.1 9.6e-09 35.3 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EKX53602.1 - 1.2e-06 28.8 0.2 6.4e-06 26.5 0.4 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EKX53602.1 - 0.024 14.6 0.0 0.079 12.9 0.0 1.8 2 0 0 2 2 2 0 FR47-like protein MFS_1 PF07690.16 EKX53604.1 - 2.2e-33 115.6 40.8 6.3e-24 84.6 13.5 2.7 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EKX53604.1 - 3.7e-09 36.0 7.6 3.7e-09 36.0 7.6 3.2 2 1 1 3 3 3 3 Sugar (and other) transporter PDZ_2 PF13180.6 EKX53605.1 - 0.0024 18.2 0.0 0.006 16.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain LPP PF04728.13 EKX53605.1 - 0.24 11.8 0.1 0.24 11.8 0.1 2.8 4 0 0 4 4 4 0 Lipoprotein leucine-zipper Occludin_ELL PF07303.13 EKX53605.1 - 0.35 11.6 13.8 0.069 13.9 4.0 3.1 1 1 1 3 3 3 0 Occludin homology domain GAS PF13851.6 EKX53605.1 - 0.53 9.6 19.0 0.75 9.1 5.3 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4201 PF13870.6 EKX53605.1 - 1.6 8.5 18.5 3.3 7.4 14.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) TBCA PF02970.16 EKX53605.1 - 2.9 8.3 17.5 18 5.8 7.6 2.6 2 1 1 3 3 3 0 Tubulin binding cofactor A Fez1 PF06818.15 EKX53605.1 - 4 7.8 18.9 28 5.1 18.9 2.0 1 1 0 1 1 1 0 Fez1 DUF4446 PF14584.6 EKX53605.1 - 4.2 7.4 10.2 6.1 6.8 2.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) FapA PF03961.13 EKX53605.1 - 6.4 5.3 12.2 2.1 6.9 7.9 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A APG6_N PF17675.1 EKX53605.1 - 7.6 7.1 22.7 1.9 9.0 18.6 1.9 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF883 PF05957.13 EKX53605.1 - 8.2 7.1 12.0 8.7 7.0 0.3 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) ANAPC_CDC26 PF10471.9 EKX53606.1 - 0.33 11.8 21.0 5.3 7.9 8.7 4.2 2 2 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 RCC1 PF00415.18 EKX53607.1 - 4.1e-41 139.4 14.2 3.3e-10 40.4 0.0 5.1 4 1 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX53607.1 - 2.2e-24 84.6 10.7 1.3e-07 31.3 0.7 4.0 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat Peptidase_C25_C PF03785.14 EKX53607.1 - 0.015 15.1 0.0 0.81 9.6 0.0 2.6 3 0 0 3 3 3 0 Peptidase family C25, C terminal ig-like domain Myb_DNA-binding PF00249.31 EKX53608.1 - 3.8e-08 33.4 0.1 3.6e-07 30.3 0.1 2.3 1 1 0 1 1 1 1 Myb-like DNA-binding domain DUF1295 PF06966.12 EKX53609.1 - 3.9e-50 170.6 8.6 5.7e-50 170.0 8.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 EKX53609.1 - 1.4e-05 25.1 0.3 1.4e-05 25.1 0.3 1.8 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 EKX53609.1 - 0.00028 21.3 1.2 0.0011 19.3 0.1 2.5 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EKX53609.1 - 0.006 17.0 0.3 0.006 17.0 0.3 2.3 3 0 0 3 3 3 1 Phospholipid methyltransferase DUF1749 PF08538.10 EKX53610.1 - 1.1e-62 211.9 0.0 1.2e-62 211.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 EKX53610.1 - 6.2e-07 30.2 0.0 8.5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EKX53610.1 - 4.7e-06 26.0 0.0 9e-06 25.1 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF900 PF05990.12 EKX53610.1 - 0.0083 15.7 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) LIDHydrolase PF10230.9 EKX53610.1 - 0.011 15.3 0.0 0.22 11.1 0.0 2.1 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 EKX53610.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_1 PF00561.20 EKX53610.1 - 0.016 14.8 0.0 0.033 13.8 0.0 1.6 2 1 0 2 2 2 0 alpha/beta hydrolase fold Thioesterase PF00975.20 EKX53610.1 - 0.073 13.2 0.1 0.29 11.2 0.1 1.9 1 1 1 2 2 2 0 Thioesterase domain DUF3089 PF11288.8 EKX53610.1 - 0.13 11.8 0.1 0.27 10.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) Epimerase_2 PF02350.19 EKX53611.1 - 9.2e-15 54.3 0.1 1.5e-13 50.3 0.0 2.5 3 0 0 3 3 3 1 UDP-N-acetylglucosamine 2-epimerase Glyco_tranf_2_3 PF13641.6 EKX53611.1 - 2.2e-07 31.0 0.5 4.7e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 O-FucT PF10250.9 EKX53611.1 - 8.2e-06 25.7 0.0 3.3e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glycos_transf_2 PF00535.26 EKX53611.1 - 0.0013 18.5 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EKX53611.1 - 0.015 14.8 0.0 0.034 13.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 21 Zn_Tnp_IS91 PF14319.6 EKX53611.1 - 0.032 14.2 0.4 0.09 12.8 0.4 1.7 1 0 0 1 1 1 0 Transposase zinc-binding domain REV PF00424.18 EKX53611.1 - 0.11 12.6 3.1 0.29 11.2 3.1 1.7 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) zf-CCHH PF10283.9 EKX53612.1 - 3.7e-24 84.4 18.2 4.5e-11 42.5 4.6 3.6 3 0 0 3 3 3 3 PBZ domain CBM_1 PF00734.18 EKX53612.1 - 0.71 9.9 5.4 14 5.8 0.1 3.5 3 0 0 3 3 3 0 Fungal cellulose binding domain DUF3161 PF11362.8 EKX53613.1 - 7.8e-12 45.0 0.0 1.2e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3161) SKA1 PF07160.12 EKX53613.1 - 6.1e-06 26.3 0.0 9e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 Spindle and kinetochore-associated protein 1 Na_Ca_ex PF01699.24 EKX53614.1 - 8.3e-36 123.2 30.8 7.2e-18 65.0 16.5 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Kinesin PF00225.23 EKX53615.1 - 4.5e-90 301.9 0.2 5e-90 301.8 0.2 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX53615.1 - 1.1e-31 109.8 0.2 5.5e-31 107.5 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding Ank_2 PF12796.7 EKX53616.1 - 1.7e-10 41.3 0.0 2.9e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX53616.1 - 3.8e-09 36.6 0.7 1.2e-05 25.4 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX53616.1 - 2.2e-08 33.7 0.1 0.0075 16.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EKX53616.1 - 1.9e-07 31.5 0.2 0.0035 17.9 0.2 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX53616.1 - 1.5e-06 28.3 0.1 0.0021 18.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Aminotran_1_2 PF00155.21 EKX53618.1 - 3.9e-78 263.2 0.0 4.8e-78 262.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Peptidase_C3 PF00548.20 EKX53619.1 - 0.2 11.6 1.4 0.62 10.0 1.4 1.8 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) DUF2489 PF10675.9 EKX53620.1 - 0.003 17.5 0.5 0.0039 17.1 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2489) Golgin_A5 PF09787.9 EKX53620.1 - 0.0033 16.9 2.5 0.0042 16.6 2.5 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 Jnk-SapK_ap_N PF09744.9 EKX53620.1 - 0.0054 17.0 1.8 0.0062 16.8 1.8 1.2 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 GPS2_interact PF15784.5 EKX53620.1 - 0.0055 17.1 0.6 0.013 15.9 0.6 1.6 1 0 0 1 1 1 1 G-protein pathway suppressor 2-interacting domain Phage_30_3 PF08010.11 EKX53620.1 - 0.027 14.3 3.0 0.17 11.7 1.1 2.1 1 1 1 2 2 2 0 Bacteriophage protein GP30.3 DUF305 PF03713.13 EKX53620.1 - 0.4 10.8 3.4 0.62 10.2 3.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF305) DivIC PF04977.15 EKX53620.1 - 0.89 9.4 4.0 1.9 8.3 4.0 1.5 1 0 0 1 1 1 0 Septum formation initiator DUF4632 PF15451.6 EKX53620.1 - 4.7 7.3 6.1 13 5.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) Tektin PF03148.14 EKX53621.1 - 2.6e-57 194.3 34.8 3.6e-57 193.9 34.8 1.1 1 0 0 1 1 1 1 Tektin family BRE1 PF08647.11 EKX53621.1 - 0.2 11.8 27.7 0.22 11.6 2.3 4.9 3 1 0 4 4 4 0 BRE1 E3 ubiquitin ligase GlcNAc-1_reg PF18440.1 EKX53621.1 - 0.27 11.5 4.5 4.2 7.7 0.0 3.8 4 1 0 4 4 4 0 Putative GlcNAc-1 phosphotransferase regulatory domain IL15 PF02372.15 EKX53621.1 - 0.94 9.5 7.6 0.22 11.5 0.2 3.0 2 1 1 3 3 3 0 Interleukin 15 Fib_alpha PF08702.10 EKX53621.1 - 2.9 8.1 18.6 3.7 7.7 3.4 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family CwsA PF10814.8 EKX53621.1 - 6.6 6.9 8.0 12 6.0 0.3 3.3 3 0 0 3 3 3 0 Cell wall synthesis protein CwsA GPI-anchored PF10342.9 EKX53622.1 - 0.00049 20.8 0.0 0.024 15.4 0.0 2.3 2 0 0 2 2 2 2 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Peptidase_M66 PF10462.9 EKX53623.1 - 0.0002 20.5 0.4 0.00043 19.3 0.4 1.5 1 0 0 1 1 1 1 Peptidase M66 DUF4457 PF14652.6 EKX53623.1 - 0.011 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4457) Reprolysin_2 PF13574.6 EKX53623.1 - 0.031 14.1 0.1 0.065 13.1 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 EKX53623.1 - 0.07 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EKX53623.1 - 0.13 12.8 0.0 0.34 11.4 0.0 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 EKX53623.1 - 0.33 9.5 0.9 0.51 8.9 0.9 1.1 1 0 0 1 1 1 0 Putative peptidase family PKD_channel PF08016.12 EKX53624.1 - 3.3e-08 32.6 2.2 4.7e-08 32.1 0.1 2.0 1 1 1 2 2 2 1 Polycystin cation channel DnaJ PF00226.31 EKX53625.1 - 6.3e-22 77.5 2.3 1.7e-12 47.3 0.2 2.5 2 0 0 2 2 2 2 DnaJ domain Pkinase PF00069.25 EKX53627.1 - 3.4e-33 115.1 0.0 6.7e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX53627.1 - 2.8e-22 79.3 0.0 4.8e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX53627.1 - 0.014 14.7 0.7 0.049 13.0 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX53627.1 - 0.021 14.7 0.1 0.18 11.7 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 EKX53627.1 - 0.041 13.5 0.0 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 RIO1 family GET2 PF08690.10 EKX53627.1 - 0.21 11.3 2.6 0.31 10.6 2.6 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Pkinase PF00069.25 EKX53628.1 - 1.1e-18 67.6 0.0 1.8e-17 63.6 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX53628.1 - 7.6e-10 38.5 0.0 1.9e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase YEATS PF03366.16 EKX53628.1 - 1.2e-06 28.4 0.2 3.3e-06 27.0 0.2 1.8 1 0 0 1 1 1 1 YEATS family Kinase-like PF14531.6 EKX53628.1 - 0.0027 17.1 0.0 0.0054 16.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like PAPA-1 PF04795.12 EKX53628.1 - 0.92 10.3 16.2 4.9 8.0 2.5 2.4 2 0 0 2 2 2 0 PAPA-1-like conserved region FCH PF00611.23 EKX53628.1 - 1 9.7 7.1 5.1 7.5 7.1 2.2 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain FAM76 PF16046.5 EKX53628.1 - 5.6 6.2 14.0 8.6 5.6 14.0 1.2 1 0 0 1 1 1 0 FAM76 protein DDE_Tnp_ISAZ013 PF07592.11 EKX53629.1 - 0.014 14.4 0.4 0.02 13.9 0.4 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain MBD_C PF14048.6 EKX53629.1 - 0.032 14.9 0.4 0.061 14.0 0.4 1.5 1 0 0 1 1 1 0 C-terminal domain of methyl-CpG binding protein 2 and 3 Phage_int_SAM_5 PF13102.6 EKX53629.1 - 0.1 13.0 2.0 0.11 12.9 0.5 1.9 1 1 1 2 2 2 0 Phage integrase SAM-like domain Ion_trans PF00520.31 EKX53630.1 - 1e-30 106.8 13.8 1.5e-30 106.3 13.8 1.2 1 0 0 1 1 1 1 Ion transport protein PH PF00169.29 EKX53630.1 - 0.0035 17.8 0.0 0.014 15.9 0.0 2.1 1 1 0 1 1 1 1 PH domain XG_FTase PF03254.13 EKX53633.1 - 0.00057 18.6 0.3 0.0013 17.5 0.1 1.6 2 0 0 2 2 2 1 Xyloglucan fucosyltransferase PTH2 PF01981.16 EKX53634.1 - 1.2e-39 135.3 0.1 1.3e-39 135.1 0.1 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 PKD_channel PF08016.12 EKX53635.1 - 1.5e-22 79.9 7.0 5.5e-10 38.5 4.9 3.0 1 1 1 3 3 3 3 Polycystin cation channel Ion_trans PF00520.31 EKX53635.1 - 1.8e-06 27.4 3.8 3.2e-06 26.6 2.2 1.9 2 0 0 2 2 2 1 Ion transport protein PKD_channel PF08016.12 EKX53636.1 - 5.1e-22 78.1 8.1 9.4e-10 37.7 4.9 3.3 1 1 1 3 3 3 3 Polycystin cation channel Ion_trans PF00520.31 EKX53636.1 - 6.9e-06 25.5 2.6 6.9e-06 25.5 2.6 1.9 2 1 1 3 3 3 1 Ion transport protein GCP_C_terminal PF04130.13 EKX53638.1 - 4e-40 138.2 8.2 4e-40 138.2 8.2 3.5 3 0 0 3 3 3 2 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EKX53638.1 - 1.6e-20 74.0 1.1 1.6e-20 74.0 1.1 2.5 2 1 0 2 2 2 1 Gamma tubulin complex component N-terminal PDZ_2 PF13180.6 EKX53639.1 - 0.00035 20.8 0.0 0.0006 20.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX53639.1 - 0.001 18.9 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX53639.1 - 0.0011 19.3 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX53639.1 - 0.054 13.5 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 Tricorn protease PDZ domain TTL PF03133.15 EKX53640.1 - 3.2e-17 62.6 0.0 1.4e-16 60.5 0.0 1.8 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EKX53640.1 - 0.0026 17.1 0.0 0.48 9.6 0.0 2.5 2 1 0 2 2 2 2 YheC/D like ATP-grasp Pro_isomerase PF00160.21 EKX53642.1 - 3.8e-49 167.0 0.0 4.3e-49 166.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HAT_KAT11 PF08214.11 EKX53643.1 - 1.2e-05 24.8 0.0 1.2e-05 24.8 0.0 2.4 4 0 0 4 4 4 1 Histone acetylation protein KASH_CCD PF14662.6 EKX53644.1 - 0.007 16.2 14.2 0.007 16.2 14.2 5.3 2 2 3 5 5 5 1 Coiled-coil region of CCDC155 or KASH DUF4250 PF14056.6 EKX53644.1 - 0.093 12.7 6.3 1.4 8.9 0.2 4.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) Rootletin PF15035.6 EKX53644.1 - 2.2 8.3 64.0 0.097 12.7 12.1 4.3 3 1 1 4 4 4 0 Ciliary rootlet component, centrosome cohesion DUF3135 PF11333.8 EKX53644.1 - 3.6 7.9 11.4 0.079 13.2 0.7 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3135) Trimer_CC PF08954.11 EKX53644.1 - 5.2 6.7 14.2 2.6 7.7 4.0 4.3 4 0 0 4 4 4 0 Trimerisation motif RWP-RK PF02042.15 EKX53645.1 - 9.9e-17 60.7 0.0 1.6e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain Rad4 PF03835.15 EKX53645.1 - 0.014 15.1 0.3 0.019 14.6 0.3 1.1 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain P22_AR_N PF10547.9 EKX53645.1 - 0.021 15.1 0.0 0.03 14.6 0.0 1.2 1 0 0 1 1 1 0 P22_AR N-terminal domain LRR_8 PF13855.6 EKX53646.1 - 5e-17 61.4 19.5 9e-09 35.0 3.1 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EKX53646.1 - 3.7e-07 30.3 9.1 0.00017 21.9 1.0 3.9 1 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX53646.1 - 0.00026 21.1 7.9 3.7 8.5 0.1 5.6 4 1 1 5 5 5 1 Leucine Rich Repeat LRR_3 PF07725.12 EKX53646.1 - 0.023 14.5 1.2 0.11 12.3 0.4 2.6 2 1 0 2 2 2 0 Leucine Rich Repeat LRR_6 PF13516.6 EKX53646.1 - 0.18 11.9 12.8 1.6 8.9 0.0 4.6 5 0 0 5 5 5 0 Leucine Rich repeat Pkinase PF00069.25 EKX53647.1 - 1.4e-31 109.8 0.0 1.8e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX53647.1 - 1.4e-19 70.4 0.0 1.6e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX53647.1 - 3.8e-06 25.9 0.0 4.9e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EKX53647.1 - 0.0004 19.8 0.0 0.0006 19.2 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EKX53647.1 - 0.002 18.1 1.9 0.055 13.4 0.3 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EKX53647.1 - 0.023 14.1 0.3 0.033 13.5 0.3 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_2 PF07719.17 EKX53648.1 - 4.9e-06 26.3 1.0 0.00014 21.7 0.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX53648.1 - 0.00028 20.6 0.7 0.011 15.6 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX53648.1 - 0.038 14.2 0.3 0.63 10.4 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EKX53648.1 - 0.055 14.1 0.3 0.068 13.8 0.3 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 EKX53648.1 - 0.073 13.2 0.1 0.13 12.5 0.1 1.4 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 EKX53648.1 - 0.081 13.3 0.3 1.2 9.7 0.3 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EKX53648.1 - 0.16 11.7 1.6 1.5 8.5 0.3 2.2 1 1 1 2 2 2 0 TPR repeat TPR_12 PF13424.6 EKX53649.1 - 2.3e-10 40.6 2.9 0.00011 22.4 0.2 1.7 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX53649.1 - 3.1e-10 39.4 1.9 1.1e-05 25.2 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX53649.1 - 4.6e-10 38.8 1.3 3e-06 26.9 0.1 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX53649.1 - 2.7e-07 30.2 4.3 0.0013 18.5 0.5 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX53649.1 - 1.1e-06 28.2 2.3 3e-05 23.6 0.1 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX53649.1 - 3.9e-05 23.4 2.7 0.00016 21.5 0.1 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat DUF3856 PF12968.7 EKX53649.1 - 0.00067 19.7 0.2 0.045 13.8 0.1 2.0 1 1 1 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_14 PF13428.6 EKX53649.1 - 0.024 15.4 1.2 0.8 10.7 0.1 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX53649.1 - 0.028 13.8 0.1 0.033 13.6 0.1 1.1 1 0 0 1 1 1 0 MalT-like TPR region TPR_15 PF13429.6 EKX53649.1 - 0.062 12.5 0.2 0.14 11.4 0.2 1.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX53649.1 - 0.11 13.0 1.3 0.19 12.3 0.4 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX53649.1 - 0.28 11.9 1.4 0.88 10.3 0.1 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat GDA1_CD39 PF01150.17 EKX53651.1 - 0.086 11.5 0.0 0.086 11.5 0.0 1.0 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family DUF2407_C PF13373.6 EKX53652.1 - 6.4e-25 88.0 1.6 1.1e-24 87.2 1.6 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain ubiquitin PF00240.23 EKX53652.1 - 8.8e-18 63.8 0.1 1.4e-17 63.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EKX53652.1 - 1.3e-08 34.5 0.1 2.1e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EKX53652.1 - 2.2e-05 24.5 0.1 4.6e-05 23.5 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EKX53652.1 - 0.00057 20.3 0.2 0.0016 18.9 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EKX53652.1 - 0.0017 18.7 0.1 0.003 17.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 EKX53652.1 - 0.0058 17.2 0.0 0.0097 16.5 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Flavi_NS4A PF01350.17 EKX53652.1 - 0.01 15.8 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A YukD PF08817.10 EKX53652.1 - 0.049 14.3 0.0 0.11 13.3 0.0 1.6 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD MtrF PF09472.10 EKX53652.1 - 0.13 11.7 0.8 0.36 10.3 0.8 1.7 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) NUDIX PF00293.28 EKX53653.1 - 5e-25 88.1 0.1 5.8e-25 87.8 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EKX53653.1 - 0.011 15.7 0.1 0.021 14.8 0.1 1.5 2 0 0 2 2 2 0 NUDIX domain DUF3155 PF11352.8 EKX53653.1 - 0.18 12.3 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3155) EGF_2 PF07974.13 EKX53654.1 - 1.9e-10 40.9 31.8 7.4e-07 29.4 13.3 2.5 1 1 2 3 3 3 2 EGF-like domain EGF_Tenascin PF18720.1 EKX53654.1 - 1.5e-05 24.9 34.5 0.0039 17.2 9.7 2.2 2 0 0 2 2 2 2 Tenascin EGF domain EGF PF00008.27 EKX53654.1 - 0.0053 17.0 10.8 0.0053 17.0 10.8 2.4 2 0 0 2 2 2 1 EGF-like domain hEGF PF12661.7 EKX53654.1 - 0.0096 16.5 28.5 0.011 16.3 7.9 3.2 3 0 0 3 3 3 2 Human growth factor-like EGF I-EGF_1 PF18372.1 EKX53654.1 - 0.053 13.6 6.6 0.053 13.6 6.6 3.6 3 0 0 3 3 3 0 Integrin beta epidermal growth factor like domain 1 Laminin_EGF PF00053.24 EKX53654.1 - 0.066 13.4 24.8 0.079 13.1 10.4 2.1 1 1 1 2 2 2 0 Laminin EGF domain EB PF01683.18 EKX53654.1 - 2.4 8.5 24.5 0.18 12.1 4.5 2.4 1 1 1 2 2 2 0 EB module DUF2273 PF10031.9 EKX53655.1 - 0.032 14.2 1.8 0.053 13.5 1.8 1.3 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) MFS_1 PF07690.16 EKX53656.1 - 3.4e-09 36.1 22.0 5.7e-09 35.4 22.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily 5TM-5TMR_LYT PF07694.12 EKX53656.1 - 0.0065 16.0 3.5 0.24 10.9 0.0 3.2 2 1 0 3 3 3 1 5TMR of 5TMR-LYT MFS_3 PF05977.13 EKX53656.1 - 0.0093 14.4 3.8 0.013 14.0 3.8 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector Chorion_3 PF05387.11 EKX53656.1 - 0.032 13.9 3.8 0.046 13.3 3.8 1.1 1 0 0 1 1 1 0 Chorion family 3 Sugar_tr PF00083.24 EKX53656.1 - 0.074 11.9 4.0 0.075 11.9 1.2 2.0 1 1 1 2 2 2 0 Sugar (and other) transporter DUF1772 PF08592.11 EKX53656.1 - 1.4 9.2 7.4 14 6.0 0.0 2.8 2 2 0 3 3 3 0 Domain of unknown function (DUF1772) YqfQ PF14181.6 EKX53656.1 - 2.2 8.4 6.0 3.9 7.6 6.0 1.4 1 0 0 1 1 1 0 YqfQ-like protein RWP-RK PF02042.15 EKX53657.1 - 4.6e-15 55.3 0.0 7.7e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_3 PF01381.22 EKX53657.1 - 0.012 15.7 0.2 35 4.5 0.0 3.8 3 1 1 4 4 4 0 Helix-turn-helix AAA PF00004.29 EKX53659.1 - 0.083 13.3 0.0 0.25 11.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MRP-L28 PF09812.9 EKX53661.1 - 0.00082 19.5 7.1 0.0011 19.1 7.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Mitofilin PF09731.9 EKX53661.1 - 0.023 13.5 5.3 0.027 13.3 5.3 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Bact_lectin PF18483.1 EKX53662.1 - 4e-15 56.4 0.4 6.1e-15 55.8 0.4 1.3 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 EKX53662.1 - 4.2e-13 49.4 0.2 1.1e-12 48.1 0.2 1.6 1 1 0 1 1 1 1 Legume lectin domain ABC1 PF03109.16 EKX53663.1 - 1.4e-19 70.4 0.0 4.9e-19 68.6 0.0 2.0 1 1 0 1 1 1 1 ABC1 family Pkinase PF00069.25 EKX53663.1 - 0.00034 20.1 0.0 0.0097 15.3 0.0 2.6 2 1 0 2 2 2 1 Protein kinase domain PI3_PI4_kinase PF00454.27 EKX53663.1 - 0.023 14.5 0.0 0.058 13.2 0.0 1.7 2 0 0 2 2 2 0 Phosphatidylinositol 3- and 4-kinase Laminin_G_3 PF13385.6 EKX53665.1 - 1.1e-17 64.6 0.1 4.3e-14 52.9 0.1 2.9 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Ephrin_rec_like PF07699.13 EKX53665.1 - 2.1e-15 56.2 58.0 1e-07 31.6 8.8 6.1 3 1 4 7 7 7 5 Putative ephrin-receptor like TRP PF06011.12 EKX53665.1 - 2.9e-11 42.8 6.9 6.1e-11 41.7 6.9 1.5 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel Pentaxin PF00354.17 EKX53665.1 - 6.5e-05 22.7 0.0 0.057 13.1 0.0 2.3 2 0 0 2 2 2 2 Pentaxin family Laminin_G_2 PF02210.24 EKX53665.1 - 0.0023 18.5 0.0 0.01 16.4 0.0 2.1 1 0 0 1 1 1 1 Laminin G domain PC4 PF02229.16 EKX53666.1 - 7.7e-18 63.9 0.1 1.4e-17 63.1 0.1 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) ATP-synt_F PF01990.17 EKX53667.1 - 1.7e-28 98.8 0.1 2e-28 98.5 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit A-2_8-polyST PF07388.11 EKX53667.1 - 0.033 12.8 0.0 0.037 12.6 0.0 1.0 1 0 0 1 1 1 0 Alpha-2,8-polysialyltransferase (POLYST) PDZ_6 PF17820.1 EKX53668.1 - 3.9e-06 26.6 0.1 8.8e-06 25.5 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX53668.1 - 0.00057 20.2 0.1 0.0014 18.9 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX53668.1 - 0.013 15.8 0.1 0.025 14.9 0.1 1.5 1 0 0 1 1 1 0 PDZ domain EPSP_synthase PF00275.20 EKX53668.1 - 0.044 12.5 0.0 0.091 11.4 0.0 1.4 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DEC-1_N PF04625.13 EKX53668.1 - 0.11 11.5 3.4 0.2 10.7 3.4 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF1126 PF06565.12 EKX53669.1 - 9.9e-83 272.8 2.7 9.6e-28 96.1 0.1 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_1 PF00036.32 EKX53669.1 - 0.016 14.7 0.7 0.087 12.4 0.0 2.7 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 EKX53669.1 - 0.024 15.1 0.2 0.078 13.4 0.2 2.0 1 0 0 1 1 1 0 EF-hand domain pair Peptidase_C2 PF00648.21 EKX53670.1 - 2.6e-40 138.3 0.0 4.2e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 EKX53670.1 - 1.4e-09 38.4 0.2 8.8e-05 22.8 0.0 2.8 2 0 0 2 2 2 2 Calpain large subunit, domain III DUF1118 PF06549.12 EKX53672.1 - 3.2e-18 66.1 5.0 3.2e-18 66.1 5.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1118) PAS_9 PF13426.7 EKX53674.1 - 0.00041 20.6 0.0 0.00082 19.6 0.0 1.5 1 1 0 1 1 1 1 PAS domain PAS PF00989.25 EKX53674.1 - 0.061 13.3 0.0 0.084 12.9 0.0 1.2 1 0 0 1 1 1 0 PAS fold DUF1955 PF09205.10 EKX53677.1 - 0.12 12.1 0.1 0.13 12.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) Mito_carr PF00153.27 EKX53679.1 - 1.3e-34 117.9 0.1 4.2e-19 68.3 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein zf-RING_2 PF13639.6 EKX53680.1 - 7e-10 39.1 7.1 7e-10 39.1 7.1 2.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 EKX53680.1 - 4.6e-08 32.8 4.0 4.6e-08 32.8 4.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX53680.1 - 1.5e-07 31.3 4.0 2.1e-07 30.8 2.4 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EKX53680.1 - 4e-07 29.8 8.2 4e-07 29.8 8.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EKX53680.1 - 1.6e-06 28.1 2.6 5e-06 26.5 2.6 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EKX53680.1 - 2.2e-06 27.8 3.6 7.9e-06 26.1 3.6 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EKX53680.1 - 2.3e-06 27.3 6.4 6.8e-06 25.8 6.4 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EKX53680.1 - 3.6e-06 26.7 6.1 3.6e-06 26.7 6.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EKX53680.1 - 5.4e-06 26.5 7.1 5.4e-06 26.5 7.1 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Vps51 PF08700.11 EKX53680.1 - 5.7e-05 23.1 0.4 0.00018 21.5 0.4 1.9 1 0 0 1 1 1 1 Vps51/Vps67 zf-RING_5 PF14634.6 EKX53680.1 - 0.00011 22.1 5.6 0.00011 22.1 5.6 2.5 2 0 0 2 2 2 1 zinc-RING finger domain Sec5 PF15469.6 EKX53680.1 - 0.00015 21.6 4.3 0.34 10.7 0.0 3.7 3 1 0 4 4 4 2 Exocyst complex component Sec5 zf-RING_4 PF14570.6 EKX53680.1 - 0.34 10.8 4.7 0.99 9.3 4.7 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 EKX53680.1 - 0.61 10.0 3.6 1.7 8.5 3.6 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein PHF5 PF03660.14 EKX53680.1 - 0.62 10.3 4.4 11 6.3 0.0 2.6 1 1 1 2 2 2 0 PHF5-like protein Zn_ribbon_17 PF17120.5 EKX53680.1 - 0.95 9.1 8.5 0.39 10.4 5.4 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Fib_alpha PF08702.10 EKX53681.1 - 0.47 10.6 2.9 1.3 9.2 2.8 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Kinesin PF00225.23 EKX53682.1 - 2.1e-116 388.5 0.8 2.3e-116 388.3 0.8 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX53682.1 - 5.9e-25 88.0 0.0 1.1e-24 87.1 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding CTP_transf_3 PF02348.19 EKX53683.1 - 4.9e-51 173.8 0.0 5.6e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase NTP_transf_3 PF12804.7 EKX53683.1 - 1.5e-12 48.2 0.0 1.9e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 EKX53683.1 - 8e-05 22.5 0.0 9.4e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NYN_YacP PF05991.11 EKX53683.1 - 0.0038 17.2 0.1 0.0053 16.7 0.1 1.3 1 0 0 1 1 1 1 YacP-like NYN domain DUF2064 PF09837.9 EKX53683.1 - 0.23 11.3 0.6 1.2 8.9 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) AAA PF00004.29 EKX53684.1 - 1.3e-52 177.7 0.0 2.9e-37 128.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX53684.1 - 1.5e-11 45.0 0.4 1.6e-05 25.4 0.0 2.8 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EKX53684.1 - 3.2e-11 43.7 1.5 0.029 14.6 0.4 4.3 2 2 1 3 3 3 3 AAA domain AAA_lid_3 PF17862.1 EKX53684.1 - 9.3e-11 41.4 0.0 2.1e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain CDC48_N PF02359.18 EKX53684.1 - 2e-08 34.3 0.0 7.7e-08 32.4 0.0 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain NACHT PF05729.12 EKX53684.1 - 2.3e-08 34.1 2.2 0.006 16.5 0.0 3.8 2 2 1 3 3 3 2 NACHT domain AAA_2 PF07724.14 EKX53684.1 - 4.3e-08 33.5 0.0 0.0038 17.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 EKX53684.1 - 6.1e-08 32.3 0.1 0.0099 15.1 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 EKX53684.1 - 1.5e-07 31.5 0.0 0.0043 17.1 0.1 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EKX53684.1 - 2.7e-07 30.5 0.0 0.01 15.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EKX53684.1 - 3.7e-07 30.0 0.0 0.0018 18.1 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 EKX53684.1 - 1.5e-06 28.5 0.0 0.029 14.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 EKX53684.1 - 5.9e-06 25.8 0.0 0.0092 15.4 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EKX53684.1 - 6.1e-06 26.8 0.2 0.14 12.7 0.1 2.9 3 1 0 3 3 2 2 AAA domain AAA_14 PF13173.6 EKX53684.1 - 1.7e-05 24.8 0.0 0.07 13.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EKX53684.1 - 4.7e-05 23.6 0.0 0.2 11.8 0.0 2.7 2 1 0 2 2 2 2 AAA domain RuvB_N PF05496.12 EKX53684.1 - 5.1e-05 23.1 0.1 0.36 10.5 0.0 2.7 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EKX53684.1 - 5.3e-05 23.5 0.0 0.22 11.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 EKX53684.1 - 5.6e-05 23.1 0.0 0.2 11.6 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 EKX53684.1 - 8.7e-05 22.0 0.0 0.035 13.4 0.1 2.7 2 0 0 2 2 2 1 KaiC CDC48_2 PF02933.17 EKX53684.1 - 0.0001 22.0 0.1 0.00039 20.2 0.0 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), domain 2 Sigma54_activat PF00158.26 EKX53684.1 - 0.0002 21.1 0.1 0.43 10.3 0.0 2.8 3 0 0 3 3 2 2 Sigma-54 interaction domain AAA_7 PF12775.7 EKX53684.1 - 0.00021 20.9 0.1 0.43 10.1 0.0 2.8 3 0 0 3 3 2 2 P-loop containing dynein motor region NB-ARC PF00931.22 EKX53684.1 - 0.00034 19.9 0.2 0.9 8.7 0.1 2.5 2 1 0 2 2 2 2 NB-ARC domain DUF2075 PF09848.9 EKX53684.1 - 0.00048 19.5 0.2 0.27 10.4 0.0 2.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 EKX53684.1 - 0.0008 18.7 0.0 0.84 8.9 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin ATPase_2 PF01637.18 EKX53684.1 - 0.0011 18.9 0.4 11 5.8 0.0 3.6 2 2 2 4 4 4 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 EKX53684.1 - 0.0028 18.1 0.0 3 8.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EKX53684.1 - 0.0035 17.1 0.0 1.8 8.3 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Bac_DnaA PF00308.18 EKX53684.1 - 0.0045 16.9 0.0 0.71 9.7 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein SRP54 PF00448.22 EKX53684.1 - 0.0074 15.9 0.0 0.68 9.5 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain CPT PF07931.12 EKX53684.1 - 0.0085 15.9 0.0 0.39 10.5 0.0 2.6 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_25 PF13481.6 EKX53684.1 - 0.0098 15.5 4.0 3.7 7.1 0.0 3.9 4 0 0 4 4 4 1 AAA domain AAA_3 PF07726.11 EKX53684.1 - 0.013 15.3 0.0 2.7 7.9 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EKX53684.1 - 0.016 14.6 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.15 EKX53684.1 - 0.024 14.7 0.1 2.7 8.0 0.0 2.7 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EKX53684.1 - 0.048 14.0 0.0 2 8.8 0.1 2.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EKX53684.1 - 0.051 14.1 0.0 5.5 7.5 0.0 2.7 2 0 0 2 2 2 0 ABC transporter TniB PF05621.11 EKX53684.1 - 0.052 12.9 0.0 10 5.5 0.0 3.1 2 1 0 2 2 2 0 Bacterial TniB protein Rad17 PF03215.15 EKX53684.1 - 0.053 13.4 0.0 3 7.7 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain Molydop_binding PF01568.21 EKX53684.1 - 0.072 13.1 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain KAP_NTPase PF07693.14 EKX53684.1 - 0.073 12.3 0.2 1.6 7.9 0.0 2.6 2 2 1 3 3 3 0 KAP family P-loop domain AAA_30 PF13604.6 EKX53684.1 - 0.088 12.5 0.0 7.7 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EKX53684.1 - 0.1 12.5 0.0 14 5.6 0.0 2.6 2 0 0 2 2 2 0 NTPase EMP70 PF02990.16 EKX53685.1 - 1.3e-203 677.4 16.8 1.3e-203 677.4 16.8 1.6 2 0 0 2 2 2 1 Endomembrane protein 70 TruD PF01142.18 EKX53686.1 - 3.8e-43 147.9 0.4 5.1e-43 147.5 0.4 1.1 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) PseudoU_synth_2 PF00849.22 EKX53687.1 - 7.2e-16 58.7 0.0 2.2e-15 57.1 0.0 1.7 2 0 0 2 2 2 1 RNA pseudouridylate synthase SH3_2 PF07653.17 EKX53687.1 - 0.0046 16.6 0.0 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Peptidase_S29 PF02907.15 EKX53688.1 - 0.017 14.9 0.7 0.038 13.7 0.7 1.6 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Collagen PF01391.18 EKX53688.1 - 0.11 12.2 14.8 0.23 11.2 14.8 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) DLP_helical PF18709.1 EKX53693.1 - 9.4e-05 21.8 1.0 0.00016 21.0 1.0 1.4 1 0 0 1 1 1 1 Dynamin-like helical domain Laminin_II PF06009.12 EKX53693.1 - 0.0069 16.4 4.1 0.16 12.0 1.2 3.0 3 1 0 3 3 3 1 Laminin Domain II DUF745 PF05335.13 EKX53693.1 - 0.014 15.1 1.6 0.014 15.1 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF745) CENP-Q PF13094.6 EKX53693.1 - 0.14 12.3 3.3 0.11 12.7 0.4 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DHR10 PF18595.1 EKX53693.1 - 0.33 11.0 6.2 0.27 11.3 2.5 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain YabA PF06156.13 EKX53693.1 - 0.4 11.3 7.8 0.18 12.4 2.1 2.8 3 0 0 3 3 3 0 Initiation control protein YabA Cep57_MT_bd PF06657.13 EKX53693.1 - 3.7 8.0 12.1 7.2 7.2 3.4 2.8 3 1 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Uso1_p115_C PF04871.13 EKX53693.1 - 4.7 7.6 8.8 0.41 11.0 1.5 2.7 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Transketolase_N PF00456.21 EKX53694.1 - 1.4e-111 372.7 0.9 1.8e-111 372.3 0.9 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EKX53694.1 - 1.1e-37 129.4 0.0 2.3e-37 128.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EKX53694.1 - 8.6e-09 35.3 0.0 1.8e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EKX53694.1 - 4.3e-08 32.7 0.0 1.4e-05 24.5 0.0 2.5 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 EKX53694.1 - 3.5e-07 29.5 0.2 7e-07 28.5 0.2 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 EKX53694.1 - 0.0035 17.2 1.0 0.044 13.6 1.0 2.6 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain NUC173 PF08161.12 EKX53694.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 NUC173 domain NUDIX PF00293.28 EKX53695.1 - 6.8e-11 42.3 0.7 1.1e-10 41.7 0.7 1.2 1 0 0 1 1 1 1 NUDIX domain PSD2 PF07624.11 EKX53695.1 - 0.0056 16.4 0.0 0.018 14.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1585) Glyco_tranf_2_4 PF13704.6 EKX53697.1 - 1.6e-05 25.3 1.4 0.00039 20.9 1.3 2.8 2 1 0 2 2 2 1 Glycosyl transferase family 2 Muted PF14942.6 EKX53698.1 - 0.0033 17.8 5.7 0.17 12.2 0.5 2.2 1 1 1 2 2 2 2 Organelle biogenesis, Muted-like protein CdvA PF18822.1 EKX53698.1 - 0.0078 16.0 7.5 0.56 10.0 0.6 2.9 2 1 1 3 3 3 2 CdvA-like coiled-coil domain K-box PF01486.17 EKX53698.1 - 0.0078 16.4 6.7 0.044 14.0 5.8 2.5 1 1 0 1 1 1 1 K-box region Seryl_tRNA_N PF02403.22 EKX53698.1 - 0.0089 16.3 2.2 0.0089 16.3 2.2 2.2 1 1 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain PilJ PF13675.6 EKX53698.1 - 0.011 15.8 3.5 0.23 11.5 3.5 2.8 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term CCDC144C PF14915.6 EKX53698.1 - 0.011 14.8 3.8 0.058 12.5 0.4 2.1 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region Matrilin_ccoil PF10393.9 EKX53698.1 - 0.014 15.2 4.7 6.7 6.7 0.2 3.8 2 2 2 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin Baculo_PEP_C PF04513.12 EKX53698.1 - 0.015 15.4 6.7 0.15 12.1 0.6 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF603 PF04645.12 EKX53698.1 - 0.016 14.9 1.2 0.022 14.5 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF603 DUF4164 PF13747.6 EKX53698.1 - 0.02 15.1 9.2 0.11 12.8 2.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Occludin_ELL PF07303.13 EKX53698.1 - 0.031 15.0 0.9 2.2 9.1 0.1 2.7 2 1 1 3 3 3 0 Occludin homology domain YabA PF06156.13 EKX53698.1 - 0.032 14.9 0.8 0.26 11.9 0.0 2.3 1 1 1 2 2 2 0 Initiation control protein YabA DUF1664 PF07889.12 EKX53698.1 - 0.035 14.1 7.0 0.053 13.6 1.4 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) HAUS-augmin3 PF14932.6 EKX53698.1 - 0.045 13.3 3.2 0.062 12.9 2.7 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 CorA PF01544.18 EKX53698.1 - 0.07 12.4 6.4 0.68 9.2 6.3 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Exonuc_VII_L PF02601.15 EKX53698.1 - 0.072 12.6 1.0 0.089 12.3 1.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 EKX53698.1 - 0.087 11.7 8.5 0.022 13.6 0.9 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3847 PF12958.7 EKX53698.1 - 0.13 12.4 4.1 0.52 10.5 0.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3847) bZIP_1 PF00170.21 EKX53698.1 - 0.18 11.9 5.3 1.2 9.3 0.1 3.2 3 1 0 3 3 3 0 bZIP transcription factor DUF5082 PF16888.5 EKX53698.1 - 0.19 12.0 5.3 0.1 12.9 0.9 2.5 2 2 1 3 3 3 0 Domain of unknown function (DUF5082) Syntaxin-6_N PF09177.11 EKX53698.1 - 0.2 12.2 4.7 3.3 8.3 5.2 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FlxA PF14282.6 EKX53698.1 - 0.26 11.3 5.7 6.5 6.8 0.2 2.4 2 0 0 2 2 2 0 FlxA-like protein DUF4349 PF14257.6 EKX53698.1 - 0.27 10.6 5.0 0.98 8.8 3.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) DUF948 PF06103.11 EKX53698.1 - 0.36 11.1 1.3 1.5 9.2 0.2 2.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4404 PF14357.6 EKX53698.1 - 0.36 11.5 8.3 0.51 11.0 1.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) TssO PF17561.2 EKX53698.1 - 0.39 10.8 2.2 0.92 9.6 0.4 2.0 1 1 1 2 2 2 0 Type VI secretion system, TssO COG2 PF06148.11 EKX53698.1 - 0.39 10.8 5.1 8.8 6.4 0.4 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ABC_tran_CTD PF16326.5 EKX53698.1 - 0.46 10.8 9.6 2.7 8.3 0.9 3.0 1 1 1 2 2 2 0 ABC transporter C-terminal domain Prominin PF05478.11 EKX53698.1 - 0.52 8.2 3.7 0.46 8.4 0.6 1.8 1 1 1 2 2 2 0 Prominin TBCC_N PF16752.5 EKX53698.1 - 0.52 10.8 8.0 0.79 10.2 1.5 2.4 1 1 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain HlyD_2 PF12700.7 EKX53698.1 - 0.55 8.9 6.8 0.36 9.5 0.4 2.0 1 1 0 2 2 2 0 HlyD family secretion protein HalX PF08663.10 EKX53698.1 - 0.59 10.5 8.6 1.2 9.5 2.1 3.0 2 1 1 3 3 3 0 HalX domain HSBP1 PF06825.12 EKX53698.1 - 0.84 9.5 8.3 5.1 7.0 1.5 3.9 2 2 2 4 4 4 0 Heat shock factor binding protein 1 TMPIT PF07851.13 EKX53698.1 - 0.87 8.8 3.8 0.77 9.0 0.5 1.9 1 1 1 2 2 2 0 TMPIT-like protein BLOC1_2 PF10046.9 EKX53698.1 - 1.6 9.1 7.7 1.4 9.3 1.3 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fzo_mitofusin PF04799.13 EKX53698.1 - 1.6 8.3 6.3 3.5 7.2 0.9 2.2 1 1 1 2 2 2 0 fzo-like conserved region XhlA PF10779.9 EKX53698.1 - 2.2 8.5 5.6 12 6.2 1.1 2.9 2 1 0 2 2 2 0 Haemolysin XhlA FapA PF03961.13 EKX53698.1 - 3 6.4 5.9 1.7 7.1 1.3 1.7 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF16 PF01519.16 EKX53698.1 - 3.5 8.2 5.5 73 3.9 5.5 2.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 APG6_N PF17675.1 EKX53698.1 - 3.9 8.0 10.5 1.9e+02 2.6 7.0 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region DASH_Dam1 PF08653.10 EKX53698.1 - 9.3 6.1 9.0 34 4.4 0.5 4.3 2 2 3 5 5 5 0 DASH complex subunit Dam1 Mid1 PF12929.7 EKX53699.1 - 0.00019 20.8 3.4 0.00039 19.8 3.4 1.4 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component PDZ_6 PF17820.1 EKX53700.1 - 7.4e-08 32.1 0.1 3.7e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX53700.1 - 8e-07 29.3 0.0 2.1e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Bestrophin PF01062.21 EKX53700.1 - 7.1e-05 22.3 0.1 7.1e-05 22.3 0.1 2.0 2 0 0 2 2 2 1 Bestrophin, RFP-TM, chloride channel PDZ_2 PF13180.6 EKX53700.1 - 0.0065 16.8 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain BAR_3 PF16746.5 EKX53700.1 - 0.087 12.5 8.8 0.15 11.8 8.8 1.3 1 0 0 1 1 1 0 BAR domain of APPL family Noelin-1 PF12308.8 EKX53700.1 - 2.5 8.1 7.8 3.2 7.8 5.4 2.1 1 1 1 2 2 2 0 Neurogenesis glycoprotein DUF2120 PF09893.9 EKX53700.1 - 4.8 7.3 8.5 73 3.5 8.5 2.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) Ribosomal_L37 PF08561.10 EKX53702.1 - 1.7e-13 51.1 0.2 1.7e-13 51.1 0.2 2.4 2 1 1 3 3 3 2 Mitochondrial ribosomal protein L37 ubiquitin PF00240.23 EKX53704.1 - 1.3e-11 44.1 0.0 2.6e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Fn3_assoc PF13287.6 EKX53704.1 - 2.5e-08 34.0 0.0 3.6e-07 30.2 0.0 2.3 2 0 0 2 2 2 1 Fn3 associated CHB_HEX_C_1 PF13290.6 EKX53704.1 - 6.4e-08 32.5 0.0 1.7e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Chitobiase/beta-hexosaminidase C-terminal domain DUF2407 PF10302.9 EKX53704.1 - 5.9e-06 26.8 0.0 1.3e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain WW PF00397.26 EKX53704.1 - 2.8e-05 24.1 0.4 7.4e-05 22.8 0.4 1.8 1 0 0 1 1 1 1 WW domain Rad60-SLD PF11976.8 EKX53704.1 - 3.3e-05 23.6 0.0 6.3e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PB1 PF00564.24 EKX53704.1 - 0.006 16.5 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 PB1 domain Ubiquitin_4 PF18036.1 EKX53704.1 - 0.023 14.8 0.1 0.087 12.9 0.1 2.0 1 1 0 1 1 1 0 Ubiquitin-like domain Tudor_3 PF18115.1 EKX53704.1 - 0.059 13.2 0.2 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain EF-hand_1 PF00036.32 EKX53706.1 - 2e-21 73.8 6.0 2.2e-05 23.7 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 EKX53706.1 - 1.8e-19 69.9 2.7 4.6e-13 49.4 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX53706.1 - 4.4e-19 66.7 4.0 6.3e-07 28.8 0.0 4.3 3 1 1 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 EKX53706.1 - 4.6e-15 55.2 2.7 1e-09 38.1 0.0 2.9 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX53706.1 - 7.6e-13 47.3 7.2 0.0002 20.7 0.1 3.9 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 EKX53706.1 - 3e-06 27.5 0.1 0.00014 22.1 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 EKX53706.1 - 0.00084 19.6 0.4 0.11 12.8 0.1 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EKX53706.1 - 0.0023 17.8 3.5 0.99 9.4 0.1 2.7 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand FGAR-AT_linker PF18072.1 EKX53706.1 - 0.023 15.3 0.0 0.11 13.1 0.0 2.1 1 1 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase linker domain EF-hand_11 PF08976.11 EKX53706.1 - 0.031 15.2 0.0 1.6 9.6 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain Caleosin PF05042.13 EKX53706.1 - 0.098 12.6 0.1 1.4 8.8 0.1 2.2 1 1 1 2 2 2 0 Caleosin related protein TENA_THI-4 PF03070.16 EKX53707.1 - 8.3e-25 87.8 0.0 9.4e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family IBR PF01485.21 EKX53711.1 - 3.1e-16 59.4 16.0 4e-08 33.3 3.8 3.1 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain YwqJ-deaminase PF14431.6 EKX53711.1 - 0.037 14.2 0.2 0.094 12.9 0.2 1.7 1 0 0 1 1 1 0 YwqJ-like deaminase zinc_ribbon_2 PF13240.6 EKX53711.1 - 0.31 10.8 0.1 0.31 10.8 0.1 5.5 5 1 0 5 5 5 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 EKX53711.1 - 0.44 10.5 11.8 7.2 6.7 0.1 4.9 5 0 0 5 5 5 0 PhnA Zinc-Ribbon DUF2387 PF09526.10 EKX53711.1 - 0.61 10.3 0.1 0.61 10.3 0.1 3.5 3 1 0 3 3 3 0 Probable metal-binding protein (DUF2387) Ribosomal_L37ae PF01780.19 EKX53711.1 - 0.63 10.2 3.3 2.2 8.4 0.6 2.5 2 0 0 2 2 2 0 Ribosomal L37ae protein family Mu-like_Com PF10122.9 EKX53711.1 - 1.1 8.7 0.0 1.1 8.7 0.0 3.5 4 0 0 4 4 4 0 Mu-like prophage protein Com zf-AN1 PF01428.16 EKX53711.1 - 4.1 7.7 21.5 2.5 8.4 3.2 3.2 3 1 0 3 3 3 0 AN1-like Zinc finger adh_short PF00106.25 EKX53712.1 - 1.6e-16 60.4 0.0 3.3e-14 52.8 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EKX53712.1 - 3.2e-07 30.1 0.0 0.00017 21.3 0.0 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX53712.1 - 0.00011 22.1 0.1 0.00017 21.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Peptidase_C48 PF02902.19 EKX53713.1 - 3.2e-21 76.2 1.0 1.5e-19 70.7 0.2 2.4 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain Beta_elim_lyase PF01212.21 EKX53714.1 - 2.3e-83 279.8 0.3 4.9e-72 242.7 0.0 2.1 1 1 1 2 2 2 2 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EKX53714.1 - 2.3e-07 30.3 0.0 2.5e-05 23.6 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EKX53714.1 - 1.2e-05 24.9 1.1 0.083 12.2 0.0 3.0 2 1 1 3 3 3 2 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EKX53714.1 - 0.0041 16.1 0.1 0.065 12.2 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Whib PF02467.16 EKX53714.1 - 0.031 14.9 0.1 0.069 13.8 0.1 1.6 1 0 0 1 1 1 0 Transcription factor WhiB OKR_DC_1 PF01276.20 EKX53714.1 - 0.038 12.7 0.0 0.049 12.4 0.0 1.1 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.20 EKX53714.1 - 0.12 10.9 0.0 0.36 9.3 0.0 1.8 2 1 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme RNA_pol_Rpb6 PF01192.22 EKX53714.1 - 0.17 11.9 0.1 8.6 6.4 0.0 2.6 2 0 0 2 2 2 0 RNA polymerase Rpb6 AIG2_2 PF13772.6 EKX53715.1 - 5.6e-06 26.7 0.0 9.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family RabGAP-TBC PF00566.18 EKX53716.1 - 5.9e-34 117.6 0.0 8.8e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ion_trans PF00520.31 EKX53717.1 - 5.6e-12 45.4 11.8 9e-12 44.7 11.8 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX53717.1 - 1.6e-11 44.0 1.1 1.6e-11 44.0 1.1 2.1 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 EKX53717.1 - 2e-06 27.8 0.0 8e-06 25.8 0.0 2.1 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PspC PF04024.12 EKX53717.1 - 0.089 12.6 0.6 0.33 10.8 0.6 2.0 1 0 0 1 1 1 0 PspC domain SlyX PF04102.12 EKX53717.1 - 0.41 11.3 4.6 0.21 12.2 0.8 2.6 2 0 0 2 2 2 0 SlyX MerR-DNA-bind PF09278.11 EKX53717.1 - 0.9 10.1 4.0 1.9 9.1 1.8 2.7 2 0 0 2 2 2 0 MerR, DNA binding DUF5362 PF17319.2 EKX53717.1 - 1.3 8.9 6.2 2.9 7.8 2.8 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5362) RYDR_ITPR PF01365.21 EKX53718.1 - 1.1e-27 96.8 16.3 7.3e-16 58.2 1.9 3.3 3 0 0 3 3 3 2 RIH domain Ins145_P3_rec PF08709.11 EKX53718.1 - 9.4e-15 54.4 0.0 4.5e-11 42.4 0.0 3.1 2 1 0 2 2 2 2 Inositol 1,4,5-trisphosphate/ryanodine receptor RIH_assoc PF08454.11 EKX53718.1 - 3.9e-14 52.3 3.7 5.6e-11 42.2 0.0 5.0 3 1 0 3 3 3 2 RyR and IP3R Homology associated MIR PF02815.19 EKX53718.1 - 5.2e-10 39.5 0.1 6.9e-09 35.8 0.0 2.3 2 0 0 2 2 2 1 MIR domain Flavi_capsid PF01003.19 EKX53718.1 - 0.093 12.5 0.7 0.4 10.4 0.1 2.3 2 0 0 2 2 2 0 Flavivirus capsid protein C EF-hand_6 PF13405.6 EKX53719.1 - 1.8e-07 30.5 0.2 5.1e-05 22.9 0.1 3.1 2 1 1 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 EKX53719.1 - 1.6e-06 28.4 0.2 4e-06 27.2 0.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX53719.1 - 2.8e-06 26.5 0.6 0.0019 17.6 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 EKX53719.1 - 0.0013 18.2 0.4 1 9.0 0.3 2.7 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 EKX53719.1 - 0.035 14.4 0.3 0.41 11.0 0.1 2.5 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF2046 PF09755.9 EKX53719.1 - 0.041 13.1 0.5 0.063 12.5 0.2 1.4 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Sigma70_ner PF04546.13 EKX53719.1 - 0.044 13.7 1.0 0.12 12.2 0.4 1.8 1 1 0 2 2 2 0 Sigma-70, non-essential region HMG_box_2 PF09011.10 EKX53719.1 - 0.082 13.5 0.1 0.15 12.6 0.1 1.5 1 0 0 1 1 1 0 HMG-box domain Ephrin_rec_like PF07699.13 EKX53720.1 - 1.1e-45 153.2 90.5 3.2e-08 33.2 9.3 10.3 1 1 11 12 12 12 12 Putative ephrin-receptor like NCD3G PF07562.14 EKX53720.1 - 6.7e-14 51.6 64.8 0.0021 18.0 2.8 8.5 1 1 10 12 12 12 12 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX53720.1 - 1e-09 38.6 58.4 0.38 11.2 0.1 11.4 4 4 4 10 10 10 8 TNFR/NGFR cysteine-rich region VSP PF03302.13 EKX53720.1 - 1.1e-05 24.5 73.6 0.0068 15.3 16.5 4.2 1 1 3 4 4 4 4 Giardia variant-specific surface protein DUF326 PF03860.16 EKX53720.1 - 0.052 13.5 0.8 0.052 13.5 0.8 5.0 5 0 0 5 5 5 0 Domain of Unknown Function (DUF326) DUF2318 PF10080.9 EKX53720.1 - 2.1 8.5 58.4 0.16 12.1 1.3 7.2 1 1 6 7 7 7 0 Predicted membrane protein (DUF2318) Inositol_P PF00459.25 EKX53721.1 - 4.1e-24 85.5 0.6 8.6e-12 45.1 0.0 2.3 1 1 1 2 2 2 2 Inositol monophosphatase family Inositol_P PF00459.25 EKX53723.1 - 3.5e-25 89.1 0.4 1e-12 48.2 0.0 2.2 1 1 1 2 2 2 2 Inositol monophosphatase family EMP70 PF02990.16 EKX53724.1 - 1e-191 638.1 6.6 1e-191 638.1 6.6 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 NADH_4Fe-4S PF10589.9 EKX53725.1 - 0.04 14.0 0.2 0.18 11.9 0.1 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Ssu72 PF04722.13 EKX53726.1 - 1.1e-77 259.9 0.5 1.2e-77 259.8 0.5 1.0 1 0 0 1 1 1 1 Ssu72-like protein Guanylate_cyc PF00211.20 EKX53727.1 - 3.4e-07 30.0 0.1 3.6e-07 30.0 0.1 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain UPF0126 PF03458.13 EKX53728.1 - 4.4e-43 145.1 11.2 2.3e-23 81.9 0.8 2.4 2 0 0 2 2 2 2 UPF0126 domain HU-CCDC81_euk_1 PF14908.6 EKX53729.1 - 4.1e-07 30.1 0.0 1e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 HU-CCDC81_euk_2 PF18289.1 EKX53729.1 - 0.00011 22.3 0.1 0.0011 19.0 0.1 2.2 1 1 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 DUF2286 PF10051.9 EKX53729.1 - 0.066 13.0 0.5 0.14 11.9 0.5 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2286) DUF4746 PF15928.5 EKX53730.1 - 0.012 15.1 0.7 0.015 14.7 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) ISK_Channel PF02060.15 EKX53730.1 - 0.072 12.8 0.2 0.14 11.9 0.2 1.5 1 0 0 1 1 1 0 Slow voltage-gated potassium channel TnpV PF14198.6 EKX53730.1 - 0.12 12.4 2.0 0.19 11.7 1.9 1.3 1 1 0 1 1 1 0 Transposon-encoded protein TnpV GH43_C PF16369.5 EKX53731.1 - 0.0053 17.4 0.0 0.012 16.2 0.0 1.6 1 0 0 1 1 1 1 C-terminal lipocalin-like domain Kinesin PF00225.23 EKX53732.1 - 1.3e-07 30.8 0.0 7.9e-07 28.3 0.0 2.4 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EKX53732.1 - 0.00018 21.5 0.0 0.015 15.2 0.0 2.7 2 0 0 2 2 2 1 Microtubule binding DUF948 PF06103.11 EKX53732.1 - 8.5 6.7 14.2 2.6 8.4 1.0 4.5 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) TPR_19 PF14559.6 EKX53733.1 - 0.033 14.7 2.4 0.66 10.5 0.2 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat PNMA PF14893.6 EKX53733.1 - 0.055 12.9 1.1 0.082 12.3 1.1 1.2 1 0 0 1 1 1 0 PNMA TPR_12 PF13424.6 EKX53733.1 - 0.17 12.2 1.9 14 6.1 0.1 2.8 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX53733.1 - 0.98 10.4 6.9 1 10.4 0.5 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX53733.1 - 2 8.4 4.6 9.2 6.3 0.3 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat Zn-C2H2_12 PF18112.1 EKX53734.1 - 0.02 15.4 0.2 0.043 14.3 0.2 1.5 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain zf-ANAPC11 PF12861.7 EKX53734.1 - 0.028 14.5 0.5 0.34 11.0 0.1 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2H2_4 PF13894.6 EKX53734.1 - 0.073 14.0 2.0 5.4 8.1 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger DSPn PF14671.6 EKX53735.1 - 9.5e-34 116.9 0.0 2.4e-33 115.6 0.0 1.6 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EKX53735.1 - 9.2e-14 51.4 0.0 1.6e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX53735.1 - 0.00011 21.9 0.0 0.00022 20.9 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX53735.1 - 0.0053 16.9 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EKX53735.1 - 0.054 13.5 0.0 0.081 12.9 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family NUDIX_5 PF16705.5 EKX53739.1 - 0.17 11.6 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 NUDIX, or N-terminal NPxY motif-rich, region of KRIT PHF12_MRG_bd PF16737.5 EKX53739.1 - 0.24 11.2 1.5 23 4.8 0.1 2.5 2 0 0 2 2 2 0 PHD finger protein 12 MRG binding domain ORF_12_N PF18042.1 EKX53741.1 - 0.049 14.1 6.3 0.52 10.8 0.6 2.7 1 1 2 3 3 3 0 ORF 12 gene product N-terminal Glycolytic PF00274.19 EKX53742.1 - 8.1e-109 363.5 0.0 1e-108 363.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Robl_LC7 PF03259.17 EKX53743.1 - 0.0045 16.7 0.1 0.042 13.6 0.1 2.1 2 0 0 2 2 2 1 Roadblock/LC7 domain UCH PF00443.29 EKX53744.1 - 2.2e-10 40.5 0.0 3.2e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Collagen PF01391.18 EKX53747.1 - 4.3e-07 29.6 28.7 3.3e-06 26.8 28.7 2.1 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Sel1 PF08238.12 EKX53748.1 - 1.6e-21 76.2 41.7 1.2e-06 28.9 1.7 9.2 10 0 0 10 10 10 6 Sel1 repeat Laminin_B PF00052.18 EKX53748.1 - 0.0025 17.7 1.2 0.015 15.2 0.0 2.7 3 0 0 3 3 3 1 Laminin B (Domain IV) TPR_1 PF00515.28 EKX53748.1 - 0.012 15.4 10.2 2.4 8.1 0.0 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX53748.1 - 0.033 14.5 16.7 0.098 13.0 1.7 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EKX53748.1 - 0.16 12.1 0.0 0.16 12.1 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat GPCR_chapero_1 PF11904.8 EKX53748.1 - 0.23 10.9 6.4 0.38 10.2 6.4 1.3 1 0 0 1 1 1 0 GPCR-chaperone TPR_10 PF13374.6 EKX53748.1 - 0.38 10.7 2.2 57 3.8 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EKX53748.1 - 0.58 10.5 9.6 4.6 7.7 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat RXT2_N PF08595.11 EKX53748.1 - 2.9 7.9 9.0 0.76 9.8 4.0 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal RabGAP-TBC PF00566.18 EKX53749.1 - 5.9e-30 104.5 0.0 8.9e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 EKX53749.1 - 5e-18 65.4 0.0 9.3e-18 64.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX53749.1 - 4.3e-07 29.5 0.0 6.7e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PRCC PF10253.9 EKX53750.1 - 9.7e-12 46.1 10.6 9.7e-12 46.1 10.6 2.1 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting WW PF00397.26 EKX53750.1 - 2.8e-11 43.3 1.5 5.3e-11 42.4 1.5 1.5 1 0 0 1 1 1 1 WW domain RNA_pol_A_bac PF01000.26 EKX53751.1 - 5.9e-20 71.7 0.0 1.3e-19 70.6 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EKX53751.1 - 2.3e-15 55.7 0.0 4.2e-15 54.9 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L_2 PF13656.6 EKX53751.1 - 0.068 12.9 0.0 7.7 6.4 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain adh_short_C2 PF13561.6 EKX53752.1 - 1.7e-40 139.0 0.6 1.8e-39 135.7 0.6 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EKX53752.1 - 3.8e-29 101.6 0.5 6.7e-29 100.7 0.4 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EKX53752.1 - 8.6e-07 29.0 0.1 1.3e-06 28.4 0.1 1.2 1 0 0 1 1 1 1 KR domain RRM_1 PF00076.22 EKX53753.1 - 4.1e-06 26.5 0.1 8.6e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 EKX53753.1 - 0.00018 22.1 0.8 0.00045 20.9 0.8 1.7 1 0 0 1 1 1 1 Torus domain zf-CCCH PF00642.24 EKX53753.1 - 0.0016 18.3 2.2 0.0042 17.0 2.2 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 EKX53753.1 - 0.01 16.0 0.1 0.031 14.5 0.1 1.8 1 0 0 1 1 1 0 Zinc-finger containing family RRM_3 PF08777.11 EKX53753.1 - 0.031 14.3 0.0 0.083 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA binding motif zf_CCCH_4 PF18345.1 EKX53753.1 - 0.056 13.5 4.0 0.14 12.2 4.0 1.8 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_4 PF18044.1 EKX53753.1 - 0.3 10.9 2.3 0.87 9.5 2.3 1.9 1 0 0 1 1 1 0 CCCH-type zinc finger zinc_ribbon_10 PF10058.9 EKX53753.1 - 2.2 8.1 6.4 8.8 6.1 0.9 3.0 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-RING_5 PF14634.6 EKX53753.1 - 5.8 7.0 12.0 1.7 8.7 1.0 2.6 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EKX53753.1 - 8.3 6.4 10.7 6.5 6.7 5.9 2.7 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TfoX_N PF04993.13 EKX53754.1 - 0.15 12.3 0.0 2.2 8.6 0.0 2.5 2 0 0 2 2 2 0 TfoX N-terminal domain PK PF00224.21 EKX53755.1 - 0 1652.7 30.2 9.9e-131 435.7 1.3 5.2 4 1 0 4 4 4 4 Pyruvate kinase, barrel domain PK_C PF02887.16 EKX53755.1 - 1e-55 186.9 5.0 1.1e-14 54.7 0.0 5.5 4 0 0 4 4 4 4 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EKX53755.1 - 6.3e-13 48.4 23.0 0.0061 15.7 0.7 4.7 4 0 0 4 4 4 4 HpcH/HpaI aldolase/citrate lyase family ALAD PF00490.21 EKX53755.1 - 6.6e-06 25.5 1.9 8.4 5.5 0.0 4.5 4 0 0 4 4 4 4 Delta-aminolevulinic acid dehydratase DHODB_Fe-S_bind PF10418.9 EKX53755.1 - 0.0011 18.8 2.9 32 4.5 0.0 4.7 4 0 0 4 4 4 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Prot_ATP_OB_N PF17758.1 EKX53755.1 - 0.0012 18.5 0.5 28 4.4 0.0 4.1 3 0 0 3 3 3 0 Proteasomal ATPase OB N-terminal domain SyrA PF11089.8 EKX53755.1 - 0.0076 16.3 1.9 35 4.6 0.0 3.7 3 0 0 3 3 3 0 Exopolysaccharide production repressor FAD_syn PF06574.12 EKX53755.1 - 0.011 15.7 9.0 35 4.2 0.1 4.9 5 0 0 5 5 5 0 FAD synthetase NTP_transf_3 PF12804.7 EKX53755.1 - 0.15 12.4 0.0 2.8e+02 1.8 0.0 4.7 4 0 0 4 4 4 0 MobA-like NTP transferase domain DUF2608 PF11019.8 EKX53755.1 - 0.34 10.3 3.1 2e+02 1.3 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF2608) Peptidase_M20 PF01546.28 EKX53756.1 - 1.8e-27 96.4 0.0 2.3e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EKX53756.1 - 3.4e-08 33.4 0.0 6.5e-08 32.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase dimerisation domain GATase_4 PF13230.6 EKX53757.1 - 6.5e-12 44.9 0.1 4.6e-10 38.8 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 EKX53757.1 - 3.6e-10 40.2 0.0 6.1e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain AOX PF01786.17 EKX53759.1 - 1.3e-94 315.8 0.3 1.9e-94 315.3 0.3 1.2 1 0 0 1 1 1 1 Alternative oxidase EF-hand_1 PF00036.32 EKX53759.1 - 1.9e-11 42.6 0.3 0.00013 21.2 0.3 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EKX53759.1 - 2.8e-11 42.4 0.2 0.00048 19.8 0.2 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 EKX53759.1 - 8.1e-10 39.0 0.8 3.7e-06 27.3 0.3 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EKX53759.1 - 0.00017 21.4 1.3 0.73 9.7 0.1 3.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX53759.1 - 0.00019 20.8 1.3 0.48 10.0 0.3 3.3 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 EKX53759.1 - 1.2 9.5 8.7 0.14 12.5 0.5 3.2 3 1 1 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region Lipoprotein_6 PF01441.19 EKX53760.1 - 0.028 14.4 0.3 0.077 13.0 0.0 1.8 2 0 0 2 2 2 0 Lipoprotein SR-25 PF10500.9 EKX53760.1 - 0.23 11.1 16.0 0.3 10.7 16.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4614 PF15391.6 EKX53760.1 - 1.9 8.5 12.8 1.5 8.7 11.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4614) EF-hand_6 PF13405.6 EKX53761.1 - 0.0087 15.9 0.5 0.031 14.2 0.2 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EKX53761.1 - 0.06 12.9 1.1 0.09 12.4 0.1 1.9 2 0 0 2 2 2 0 EF hand MASE1 PF05231.14 EKX53761.1 - 4.6 6.3 14.9 0.17 11.0 7.6 2.2 2 1 1 3 3 3 0 MASE1 RWP-RK PF02042.15 EKX53762.1 - 4e-15 55.5 0.0 7e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX53763.1 - 4.4e-15 55.4 0.0 7.9e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain VPS28 PF03997.12 EKX53764.1 - 7.1e-44 149.7 0.0 8.9e-44 149.4 0.0 1.1 1 0 0 1 1 1 1 VPS28 protein Ribosomal_S11 PF00411.19 EKX53765.1 - 2.4e-46 156.6 1.1 3.2e-46 156.2 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.9 EKX53765.1 - 0.022 13.8 0.0 0.028 13.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) CBM_25 PF03423.13 EKX53765.1 - 0.038 14.2 0.0 0.095 13.0 0.0 1.6 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) Reprolysin_4 PF13583.6 EKX53766.1 - 0.076 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DoxX_2 PF13564.6 EKX53767.1 - 0.00047 20.2 5.0 0.12 12.5 2.1 2.1 2 0 0 2 2 2 2 DoxX-like family DUF747 PF05346.11 EKX53767.1 - 0.026 14.0 0.3 0.03 13.8 0.3 1.2 1 0 0 1 1 1 0 Eukaryotic membrane protein family RseC_MucC PF04246.12 EKX53767.1 - 0.89 9.5 2.8 0.51 10.3 0.9 1.5 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DoxX PF07681.12 EKX53767.1 - 3.4 8.3 8.2 2.2 8.9 0.5 2.5 3 0 0 3 3 3 0 DoxX Med20 PF08612.11 EKX53768.1 - 0.15 11.4 0.0 0.49 9.7 0.0 1.7 1 1 1 2 2 2 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Tad PF13400.6 EKX53768.1 - 2.7 8.4 0.0 2.7 8.4 0.0 4.0 4 0 0 4 4 4 0 Putative Flp pilus-assembly TadE/G-like F_bP_aldolase PF01116.20 EKX53769.1 - 2.2e-85 286.6 0.0 2.7e-85 286.3 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DUF1525 PF07511.11 EKX53771.1 - 0.13 12.4 2.8 0.08 13.1 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) CAML PF14963.6 EKX53771.1 - 0.87 9.7 5.5 1.1 9.3 5.1 1.3 1 1 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand PTS_IIA PF02255.16 EKX53771.1 - 1 9.5 6.6 0.47 10.5 3.5 1.9 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit DUF2188 PF09954.9 EKX53771.1 - 4.2 7.6 8.0 1.2 9.3 0.5 2.8 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2188) Rsa3 PF14615.6 EKX53772.1 - 2.3e-10 39.9 0.0 5.5e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 Ribosome-assembly protein 3 Ank_2 PF12796.7 EKX53773.1 - 2.2e-12 47.4 1.0 5.3e-11 43.0 0.3 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX53773.1 - 7.3e-09 35.7 0.1 1.7e-05 25.0 0.0 3.5 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX53773.1 - 1e-07 32.4 0.2 0.003 18.1 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX53773.1 - 1.8e-07 30.9 0.2 0.0004 20.6 0.0 3.7 3 1 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EKX53773.1 - 0.00014 22.1 0.7 0.026 15.0 0.0 3.0 3 1 0 3 3 3 1 Ankyrin repeat Las1 PF04031.13 EKX53774.1 - 8.3e-30 103.9 0.3 1e-29 103.6 0.3 1.0 1 0 0 1 1 1 1 Las1-like adh_short PF00106.25 EKX53776.1 - 9.8e-11 41.5 0.0 4e-05 23.2 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EKX53776.1 - 2.9e-05 23.7 0.0 0.00035 20.2 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EKX53776.1 - 0.047 13.1 0.0 0.058 12.9 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Phage_TAC_9 PF10876.8 EKX53776.1 - 0.085 12.9 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Phage tail assemb.y chaperone protein, TAC zf-HC5HC2H PF13771.6 EKX53777.1 - 1.2e-09 38.3 3.0 1.2e-09 38.3 1.0 2.2 2 0 0 2 2 2 1 PHD-like zinc-binding domain SPRY PF00622.28 EKX53777.1 - 1.1e-07 32.0 0.0 1.1e-06 28.8 0.1 2.3 2 0 0 2 2 2 1 SPRY domain zf-HC5HC2H_2 PF13832.6 EKX53777.1 - 2e-07 31.1 2.0 2.8e-07 30.7 0.6 2.0 2 0 0 2 2 2 1 PHD-zinc-finger like domain LysM PF01476.20 EKX53777.1 - 0.00016 21.7 0.0 1.1 9.4 0.0 3.3 3 0 0 3 3 3 2 LysM domain Agenet PF05641.12 EKX53777.1 - 0.023 15.2 0.8 8.4 6.9 0.0 3.2 3 0 0 3 3 3 0 Agenet domain SDA1 PF05285.12 EKX53777.1 - 4.2 6.7 20.3 0.27 10.6 11.4 2.3 2 0 0 2 2 2 0 SDA1 Amidinotransf PF02274.17 EKX53778.1 - 3e-05 23.3 0.0 0.003 16.7 0.0 2.2 2 0 0 2 2 2 2 Amidinotransferase BIR PF00653.21 EKX53779.1 - 0.0018 18.9 0.0 0.0038 17.8 0.0 1.5 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain SHIPPO-rpt PF07004.12 EKX53780.1 - 7.7e-13 48.7 25.5 0.23 12.4 0.6 7.4 7 0 0 7 7 7 6 Sperm-tail PG-rich repeat UCH PF00443.29 EKX53782.1 - 1.1e-33 116.8 0.1 1.8e-33 116.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EKX53782.1 - 2.5e-12 46.9 1.0 5e-12 46.0 1.0 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EKX53782.1 - 7.1e-05 22.5 0.0 0.19 11.3 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Ebola_NP PF05505.12 EKX53782.1 - 0.004 15.5 0.1 0.0062 14.9 0.1 1.2 1 0 0 1 1 1 1 Ebola nucleoprotein RWP-RK PF02042.15 EKX53783.1 - 5.7e-14 51.8 0.0 1.3e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 RWP-RK domain RWP-RK PF02042.15 EKX53784.1 - 1.7e-14 53.5 0.0 2.8e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain DUF3737 PF12541.8 EKX53784.1 - 0.053 12.7 0.3 0.071 12.3 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3737) C2 PF00168.30 EKX53785.1 - 0.00014 22.1 0.4 0.00042 20.6 0.0 1.9 2 1 0 2 2 2 1 C2 domain C2 PF00168.30 EKX53786.1 - 1.5e-52 176.2 0.0 1.1e-14 54.6 0.0 4.8 4 1 0 4 4 4 4 C2 domain eIF-6 PF01912.18 EKX53788.1 - 1.1e-80 269.7 0.8 1.5e-80 269.3 0.5 1.3 2 0 0 2 2 2 1 eIF-6 family Colicin_immun PF09204.10 EKX53789.1 - 1 9.9 4.2 2.8 8.5 1.4 2.4 2 0 0 2 2 2 0 Bacterial self-protective colicin-like immunity RAG1_imp_bd PF12560.8 EKX53789.1 - 7.7 6.0 11.4 0.12 11.9 2.3 2.1 2 0 0 2 2 2 0 RAG1 importin binding AAR2 PF05282.11 EKX53791.1 - 0.012 15.0 0.5 0.014 14.9 0.5 1.1 1 0 0 1 1 1 0 AAR2 protein Ferritin PF00210.24 EKX53791.1 - 0.077 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Ferritin-like domain SUI1 PF01253.22 EKX53792.1 - 4.5e-16 59.1 0.1 9.5e-16 58.1 0.1 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 EKX53792.1 - 2.6e-05 24.8 0.8 7.2e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Pre-PUA-like domain DUF4519 PF15012.6 EKX53792.1 - 0.055 13.6 3.6 0.15 12.2 3.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Img2 PF05046.14 EKX53792.1 - 0.13 12.6 0.0 0.38 11.1 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) Cauli_VI PF01693.16 EKX53793.1 - 5.8e-11 42.5 0.1 1.2e-10 41.5 0.1 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin DEAD PF00270.29 EKX53795.1 - 3.5e-21 75.8 0.0 6.1e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX53795.1 - 2.7e-20 72.8 0.0 3.6e-17 62.7 0.0 2.9 2 1 1 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 EKX53795.1 - 0.0031 17.5 0.0 0.052 13.6 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit O-FucT PF10250.9 EKX53796.1 - 6.1e-06 26.2 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase HLH PF00010.26 EKX53797.1 - 1.1e-16 60.5 9.9 1.8e-09 37.4 2.1 2.6 2 0 0 2 2 2 2 Helix-loop-helix DNA-binding domain DUF4558 PF15104.6 EKX53797.1 - 0.033 14.2 1.4 5.7 7.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4558) ABC1 PF03109.16 EKX53799.1 - 4.5e-21 75.2 0.0 1.1e-20 74.0 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Pkinase_Tyr PF07714.17 EKX53799.1 - 0.0011 18.3 0.0 0.42 9.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EKX53799.1 - 0.0034 17.3 0.1 0.0069 16.3 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EKX53799.1 - 0.0084 15.7 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 EKX53799.1 - 0.12 11.7 0.1 0.22 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein kinase domain PH PF00169.29 EKX53800.1 - 1.5e-08 35.1 0.0 9.7e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 PH domain Ank_4 PF13637.6 EKX53800.1 - 4.3e-08 33.5 0.1 1.2e-07 32.1 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX53800.1 - 2.7e-05 24.4 0.2 5.8e-05 23.3 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX53800.1 - 5.3e-05 23.7 0.1 0.00011 22.7 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) PDZ_6 PF17820.1 EKX53800.1 - 6.3e-05 22.7 0.6 0.0002 21.1 0.2 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX53800.1 - 0.0005 20.3 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Ank PF00023.30 EKX53800.1 - 0.0018 18.6 0.0 0.14 12.7 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EKX53800.1 - 0.0023 18.3 0.2 0.83 10.4 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat PDZ PF00595.24 EKX53800.1 - 0.026 14.9 0.0 0.061 13.7 0.0 1.6 1 0 0 1 1 1 0 PDZ domain Trypan_PARP PF05887.11 EKX53801.1 - 0.0078 16.2 25.0 0.0078 16.2 25.0 2.0 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) Nop14 PF04147.12 EKX53801.1 - 0.068 11.4 31.8 0.092 10.9 31.8 1.2 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 EKX53801.1 - 3.3 6.4 16.1 4.4 6.0 16.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MCM_bind PF09739.9 EKX53801.1 - 7.3 4.9 10.7 9.6 4.5 10.7 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Mpp10 PF04006.12 EKX53801.1 - 8.9 4.6 32.8 0.33 9.4 26.8 1.6 2 0 0 2 2 2 0 Mpp10 protein RR_TM4-6 PF06459.12 EKX53801.1 - 9.9 5.9 18.2 1 9.1 13.5 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF3493 PF11998.8 EKX53802.1 - 5.4e-20 71.3 0.2 1e-19 70.4 0.2 1.5 1 0 0 1 1 1 1 Low psii accumulation1 / Rep27 DUF1084 PF06454.11 EKX53802.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1084) Glyco_transf_41 PF13844.6 EKX53803.1 - 4e-57 193.7 2.1 2.3e-38 131.8 0.3 3.1 1 1 2 3 3 3 2 Glycosyl transferase family 41 DUF2722 PF10846.8 EKX53803.1 - 5.9e-05 22.2 8.1 8.5e-05 21.7 8.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 EKX53803.1 - 0.00045 20.3 9.5 0.00066 19.8 9.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spore_III_AF PF09581.10 EKX53803.1 - 0.0032 17.5 1.0 0.0055 16.8 1.0 1.4 1 0 0 1 1 1 1 Stage III sporulation protein AF (Spore_III_AF) Spt20 PF12090.8 EKX53803.1 - 0.0055 16.4 19.3 0.0095 15.6 19.3 1.3 1 0 0 1 1 1 1 Spt20 family Med3 PF11593.8 EKX53803.1 - 0.013 14.7 7.4 0.024 13.9 7.4 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4834 PF16118.5 EKX53803.1 - 0.064 14.2 5.1 0.21 12.6 5.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TPR_14 PF13428.6 EKX53803.1 - 0.085 13.7 3.7 1.8 9.6 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat Presenilin PF01080.17 EKX53803.1 - 0.39 9.4 4.4 0.59 8.8 4.4 1.2 1 0 0 1 1 1 0 Presenilin BAT2_N PF07001.11 EKX53803.1 - 0.41 11.1 8.8 0.81 10.1 8.8 1.4 1 0 0 1 1 1 0 BAT2 N-terminus Activator_LAG-3 PF11498.8 EKX53803.1 - 4.6 6.1 25.7 8.2 5.3 25.7 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 GTA_holin_3TM PF11351.8 EKX53803.1 - 5.4 7.6 9.7 35 5.0 7.8 2.7 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release DivIC PF04977.15 EKX53803.1 - 7.2 6.5 15.7 16 5.3 15.7 1.6 1 0 0 1 1 1 0 Septum formation initiator NAD_binding_10 PF13460.6 EKX53804.1 - 8.3e-25 87.7 0.1 2.1e-17 63.6 0.0 2.2 1 1 1 2 2 2 2 NAD(P)H-binding DapB_N PF01113.20 EKX53804.1 - 5.7e-05 23.2 3.0 0.0043 17.2 2.6 3.4 3 1 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 EKX53804.1 - 0.0027 17.3 2.2 0.0046 16.5 0.3 2.1 2 1 0 3 3 3 1 NmrA-like family KR PF08659.10 EKX53804.1 - 0.098 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 KR domain Epimerase PF01370.21 EKX53804.1 - 0.098 12.1 0.5 0.53 9.7 0.3 2.1 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EKX53804.1 - 0.13 11.3 0.3 4.9 6.1 0.0 2.1 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family CoA_binding_2 PF13380.6 EKX53804.1 - 0.13 12.8 0.0 0.54 10.8 0.0 1.9 2 0 0 2 2 2 0 CoA binding domain HMGL-like PF00682.19 EKX53804.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 HMGL-like Polysacc_synt_2 PF02719.15 EKX53804.1 - 0.18 10.9 0.1 14 4.7 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 EKX53804.1 - 0.31 11.3 2.3 1.6 9.0 0.2 2.4 2 1 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Zn_clus PF00172.18 EKX53805.1 - 5.5e-15 55.2 25.2 6.4e-09 35.8 8.3 2.2 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Chloroa_b-bind PF00504.21 EKX53806.1 - 2.2e-41 142.1 0.1 2.8e-41 141.7 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein SGL PF08450.12 EKX53808.1 - 5.9e-06 26.1 0.0 0.00045 19.9 0.1 2.5 1 1 2 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region PQQ_2 PF13360.6 EKX53808.1 - 3.1e-05 23.7 0.0 0.0027 17.3 0.0 2.3 2 0 0 2 2 2 2 PQQ-like domain NHL PF01436.21 EKX53808.1 - 0.00036 20.4 0.1 0.23 11.6 0.0 3.7 4 0 0 4 4 4 1 NHL repeat Pkinase PF00069.25 EKX53809.1 - 6.2e-64 215.9 0.0 7.3e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX53809.1 - 4.8e-43 147.3 0.0 6.2e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX53809.1 - 3.9e-06 26.4 0.0 0.00051 19.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 EKX53809.1 - 0.021 14.2 0.2 0.048 13.0 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4630 PF15443.6 EKX53810.1 - 0.026 14.7 0.0 0.033 14.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) TPT PF03151.16 EKX53811.1 - 2.1e-09 37.1 10.7 3.2e-09 36.6 10.6 1.3 1 1 0 1 1 1 1 Triose-phosphate Transporter family DUF485 PF04341.12 EKX53811.1 - 0.098 12.6 14.2 1.5 8.8 0.6 3.6 2 1 0 3 3 3 0 Protein of unknown function, DUF485 DUF2198 PF09964.9 EKX53811.1 - 1.1 9.4 5.8 2.6 8.2 0.3 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2198) PHO4 PF01384.20 EKX53811.1 - 8.1 5.4 9.7 7.7 5.5 8.5 1.5 1 1 1 2 2 2 0 Phosphate transporter family TIG PF01833.24 EKX53813.1 - 1.9e-22 79.1 50.5 1.8e-05 24.7 0.2 14.2 14 0 0 14 14 14 8 IPT/TIG domain EPTP PF03736.17 EKX53813.1 - 3.4e-15 55.7 15.1 7.3e-06 25.9 0.3 8.7 8 0 0 8 8 8 5 EPTP domain Anth_Ig PF05587.13 EKX53813.1 - 5.9e-07 29.7 0.0 0.19 12.1 0.0 4.4 3 0 0 3 3 3 3 Anthrax receptor extracellular domain Laminin_G_3 PF13385.6 EKX53813.1 - 1.6e-05 25.1 0.0 1.6e-05 25.1 0.0 3.3 3 0 0 3 3 3 1 Concanavalin A-like lectin/glucanases superfamily Big_9 PF17963.1 EKX53813.1 - 0.16 12.8 42.9 2.8 8.8 0.0 14.3 16 0 0 16 16 16 0 Bacterial Ig domain Orai-1 PF07856.12 EKX53814.1 - 3.1e-05 23.7 7.6 4.3e-05 23.3 7.6 1.1 1 0 0 1 1 1 1 Mediator of CRAC channel activity MerE PF05052.12 EKX53814.1 - 2.3 8.2 6.9 0.94 9.5 2.2 2.2 2 0 0 2 2 2 0 MerE protein Collagen PF01391.18 EKX53815.1 - 1.2e-17 63.4 49.6 5.9e-05 22.7 49.6 2.5 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Nsp1_C PF05064.13 EKX53815.1 - 0.048 13.5 1.7 0.06 13.2 1.7 1.1 1 0 0 1 1 1 0 Nsp1-like C-terminal region Pkinase PF00069.25 EKX53816.1 - 7.8e-70 235.2 0.1 1.1e-69 234.7 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX53816.1 - 6.8e-41 140.3 0.0 9.9e-41 139.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EKX53816.1 - 3.8e-33 113.5 2.5 4.8e-19 68.3 0.0 2.9 3 0 0 3 3 3 2 POLO box duplicated region Kinase-like PF14531.6 EKX53816.1 - 1.4e-10 41.0 0.0 3.3e-06 26.6 0.0 2.2 1 1 1 2 2 2 2 Kinase-like PAZ PF02170.22 EKX53816.1 - 0.65 9.8 7.1 0.078 12.8 1.3 2.4 2 1 0 2 2 2 0 PAZ domain PRKCSH-like PF12999.7 EKX53817.1 - 3.6e-41 140.9 5.9 3.6e-41 140.9 5.9 2.2 1 1 1 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 EKX53817.1 - 1.1e-18 67.3 3.8 6.4e-17 61.7 3.8 2.6 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 EKX53817.1 - 6.9e-05 23.8 7.3 6.9e-05 23.8 7.3 2.3 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein DUF1682 PF07946.14 EKX53817.1 - 0.022 14.0 12.8 0.033 13.4 12.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) TetR_C_13 PF16925.5 EKX53817.1 - 0.054 13.4 1.6 0.11 12.4 1.6 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Ldl_recept_a PF00057.18 EKX53817.1 - 0.089 13.0 21.9 0.047 13.9 7.0 2.9 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A MRP-S26 PF14943.6 EKX53817.1 - 0.29 11.0 14.3 0.58 10.0 14.3 1.5 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Macoilin PF09726.9 EKX53817.1 - 1.9 6.9 12.5 2.8 6.4 12.5 1.2 1 0 0 1 1 1 0 Macoilin family V_ATPase_I PF01496.19 EKX53817.1 - 2.4 6.0 6.7 3.5 5.4 6.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 EKX53817.1 - 4.4 6.6 10.2 7.3 5.8 10.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SAPS PF04499.15 EKX53817.1 - 4.7 5.9 7.2 7.1 5.3 7.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2937 PF11157.8 EKX53817.1 - 7.8 6.2 6.4 17 5.1 6.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) cobW PF02492.19 EKX53819.1 - 6.9e-34 117.0 0.0 8.6e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EKX53819.1 - 0.0011 18.1 0.1 0.64 8.9 0.0 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EKX53819.1 - 0.023 15.2 0.0 0.037 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EKX53819.1 - 0.025 14.5 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 EKX53819.1 - 0.03 14.7 0.0 0.042 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 EKX53819.1 - 0.046 13.8 0.0 0.17 12.0 0.0 2.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase Pox_A32 PF04665.12 EKX53819.1 - 0.049 13.1 0.0 0.071 12.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_5 PF07728.14 EKX53819.1 - 0.073 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 EKX53819.1 - 0.16 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein TIP49 PF06068.13 EKX53819.1 - 0.19 10.9 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain SelP_N PF04592.14 EKX53819.1 - 8.9 5.6 11.7 13 5.1 11.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ras PF00071.22 EKX53820.1 - 1.5e-66 222.9 0.6 1.8e-66 222.7 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EKX53820.1 - 3e-37 127.5 0.7 5.2e-37 126.7 0.3 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EKX53820.1 - 7.5e-17 61.3 0.1 9e-17 61.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EKX53820.1 - 1.6e-06 28.1 0.3 0.029 14.3 0.1 2.3 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EKX53820.1 - 7e-06 25.6 0.1 8.4e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EKX53820.1 - 8.6e-06 25.3 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EKX53820.1 - 2e-05 24.6 0.1 3.8e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EKX53820.1 - 0.00012 21.7 0.4 0.00024 20.7 0.2 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 EKX53820.1 - 0.00049 20.5 0.1 0.4 11.1 0.0 2.3 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 EKX53820.1 - 0.0063 16.1 0.0 0.044 13.3 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 EKX53820.1 - 0.024 15.0 0.0 0.031 14.6 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 EKX53820.1 - 0.026 14.5 0.1 0.055 13.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EKX53820.1 - 0.029 13.9 0.1 0.17 11.3 0.0 2.1 2 1 1 3 3 3 0 P-loop containing dynein motor region AAA_22 PF13401.6 EKX53820.1 - 0.047 14.0 0.0 0.13 12.6 0.0 1.8 2 1 1 3 3 2 0 AAA domain LANC_like PF05147.13 EKX53820.1 - 0.049 12.2 0.1 0.077 11.6 0.0 1.4 2 0 0 2 2 2 0 Lanthionine synthetase C-like protein Dioxygenase_N PF04444.14 EKX53820.1 - 0.055 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Catechol dioxygenase N terminus ABC_tran PF00005.27 EKX53820.1 - 0.06 13.9 0.1 0.096 13.2 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 EKX53820.1 - 0.062 13.0 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 EKX53820.1 - 0.13 11.7 0.0 0.33 10.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein PspA_IM30 PF04012.12 EKX53821.1 - 3.4e-51 174.0 33.5 3.4e-51 174.0 33.5 1.3 2 0 0 2 2 2 1 PspA/IM30 family Apo-CII PF05355.11 EKX53821.1 - 0.011 15.9 0.6 0.029 14.5 0.4 1.9 2 0 0 2 2 2 0 Apolipoprotein C-II Flagellin_C PF00700.21 EKX53821.1 - 0.13 12.7 12.6 0.12 12.7 5.0 2.9 2 1 0 2 2 2 0 Bacterial flagellin C-terminal helical region FUSC PF04632.12 EKX53821.1 - 0.53 8.8 12.4 0.48 8.9 11.6 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family PhoU PF01895.19 EKX53821.1 - 0.54 10.7 11.8 0.098 13.1 1.4 3.3 2 1 0 3 3 3 0 PhoU domain RasGAP_C PF03836.15 EKX53821.1 - 0.69 10.0 15.5 1.2 9.2 4.2 2.5 1 1 1 2 2 2 0 RasGAP C-terminus Spc7 PF08317.11 EKX53821.1 - 1 8.2 30.5 1.1 8.1 15.7 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Syntaxin_2 PF14523.6 EKX53821.1 - 1.8 9.0 16.4 0.19 12.1 3.7 3.1 1 1 0 2 2 2 0 Syntaxin-like protein ERM PF00769.19 EKX53821.1 - 1.9 8.2 40.7 4.9 6.9 40.7 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Syntaxin-6_N PF09177.11 EKX53821.1 - 2.9 8.5 19.7 42 4.8 14.8 3.2 2 1 0 2 2 2 0 Syntaxin 6, N-terminal PNGaseA PF12222.8 EKX53821.1 - 2.9 6.6 6.8 3.7 6.3 6.8 1.1 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Csm1_N PF18504.1 EKX53821.1 - 4 7.9 21.5 0.23 11.8 4.3 3.6 1 1 2 3 3 3 0 Csm1 N-terminal domain Plk4_PB2 PF18409.1 EKX53821.1 - 4.5 8.0 7.0 35 5.1 0.1 2.7 2 1 1 3 3 3 0 Polo-like Kinase 4 Polo Box 2 USP8_interact PF08941.10 EKX53821.1 - 7.9 6.2 11.3 4.4 7.1 4.1 2.4 2 0 0 2 2 2 0 USP8 interacting DUF948 PF06103.11 EKX53821.1 - 8 6.8 13.6 19 5.6 1.5 3.4 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) WD40 PF00400.32 EKX53822.1 - 4.7e-60 198.1 23.3 5e-08 33.5 0.1 12.6 12 0 0 12 12 12 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX53822.1 - 3.1e-22 78.7 2.8 0.013 15.7 0.0 9.3 4 4 6 10 10 10 7 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 EKX53822.1 - 1.4e-12 47.8 0.9 3.2e-12 46.7 0.9 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 EKX53822.1 - 4.3e-07 29.2 4.6 0.78 8.6 1.0 6.2 4 2 3 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EKX53822.1 - 1.5e-06 27.8 0.0 0.29 10.4 0.0 4.0 5 0 0 5 5 5 2 WD40-like domain eIF2A PF08662.11 EKX53822.1 - 0.00045 20.1 0.0 0.5 10.2 0.0 3.9 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 EKX53822.1 - 0.009 14.8 0.9 7.1 5.2 0.0 3.9 2 2 0 4 4 4 2 Nup133 N terminal like Drf_FH1 PF06346.12 EKX53824.1 - 1 9.1 21.8 4.3 7.0 12.3 2.1 1 1 1 2 2 2 0 Formin Homology Region 1 zf-MIZ PF02891.20 EKX53825.1 - 0.018 14.8 1.0 0.018 14.8 1.0 3.0 3 1 0 3 3 3 0 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EKX53825.1 - 0.13 12.1 0.2 0.13 12.1 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Skp1 PF01466.19 EKX53826.1 - 1.3e-24 86.1 1.7 2.8e-24 85.0 1.7 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EKX53826.1 - 9.7e-16 57.7 0.1 5.8e-15 55.2 0.0 2.2 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Ndc80_HEC PF03801.13 EKX53826.1 - 0.0054 16.4 0.1 0.0094 15.6 0.0 1.5 2 0 0 2 2 2 1 HEC/Ndc80p family BTB PF00651.31 EKX53826.1 - 0.031 14.5 0.1 0.24 11.6 0.1 2.0 1 1 0 1 1 1 0 BTB/POZ domain HECA PF15353.6 EKX53826.1 - 0.039 14.2 0.0 0.072 13.3 0.0 1.5 1 0 0 1 1 1 0 Headcase protein family homologue Poty_coat PF00767.18 EKX53826.1 - 0.072 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Potyvirus coat protein F-box_5 PF18511.1 EKX53826.1 - 0.074 12.6 0.7 0.17 11.5 0.0 1.9 2 0 0 2 2 2 0 F-box MMR_HSR1 PF01926.23 EKX53827.1 - 2.3e-18 66.3 0.0 3.2e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EKX53827.1 - 1.9e-12 47.0 0.0 2.2e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EKX53827.1 - 5.8e-06 26.5 0.4 0.0039 17.3 0.2 2.2 1 1 1 2 2 2 2 Dynamin family SRPRB PF09439.10 EKX53827.1 - 1.3e-05 24.7 0.1 2.6e-05 23.7 0.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AIG1 PF04548.16 EKX53827.1 - 2.2e-05 23.9 0.0 2.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 EKX53827.1 - 3.5e-05 23.8 0.1 0.0041 17.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase NOA36 PF06524.12 EKX53827.1 - 0.023 14.0 12.3 0.027 13.8 12.3 1.1 1 0 0 1 1 1 0 NOA36 protein GTP_EFTU PF00009.27 EKX53827.1 - 0.088 12.3 0.0 1.4 8.4 0.0 2.2 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Ras PF00071.22 EKX53827.1 - 0.092 12.3 0.0 7.3 6.2 0.0 2.2 2 0 0 2 2 2 0 Ras family Cwf_Cwc_15 PF04889.12 EKX53827.1 - 0.16 11.7 13.0 0.2 11.3 13.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Torsin PF06309.11 EKX53827.1 - 0.2 11.8 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 Torsin RXT2_N PF08595.11 EKX53827.1 - 0.39 10.7 4.8 0.53 10.3 4.8 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.12 EKX53827.1 - 4.3 5.4 9.9 5 5.2 9.9 1.1 1 0 0 1 1 1 0 Nop14-like family Peptidase_C48 PF02902.19 EKX53828.1 - 2.5e-35 122.3 0.2 5.2e-35 121.3 0.2 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Kri1 PF05178.12 EKX53829.1 - 0.027 15.0 1.9 0.029 14.9 1.9 1.1 1 0 0 1 1 1 0 KRI1-like family DUF4642 PF15484.6 EKX53830.1 - 0.0039 17.4 0.3 0.01 16.1 0.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4642) Kinesin_assoc PF16183.5 EKX53830.1 - 0.43 10.7 2.2 0.54 10.4 1.1 1.7 1 1 0 2 2 2 0 Kinesin-associated Glyco_transf_41 PF13844.6 EKX53831.1 - 1e-48 166.0 0.1 3.3e-31 108.2 0.3 3.1 2 1 1 3 3 3 3 Glycosyl transferase family 41 PNTB PF02233.16 EKX53833.1 - 3.5e-171 570.2 25.0 3.5e-171 570.2 25.0 2.2 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 EKX53833.1 - 1.8e-70 236.6 0.5 1.8e-70 236.6 0.5 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 EKX53833.1 - 1.3e-44 151.8 0.3 2.7e-44 150.7 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 EKX53833.1 - 6.7e-31 106.6 6.7 6.7e-31 106.6 6.7 5.4 4 1 1 5 5 5 1 4TM region of pyridine nucleotide transhydrogenase, mitoch TPP_enzyme_M PF00205.22 EKX53833.1 - 0.00015 21.5 0.3 0.0014 18.4 0.3 2.6 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain 2-Hacid_dh_C PF02826.19 EKX53833.1 - 0.00084 18.7 0.1 0.3 10.4 0.1 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EKX53833.1 - 0.0035 16.6 0.3 0.0094 15.2 0.3 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EKX53833.1 - 0.025 15.1 0.6 0.15 12.6 0.5 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.26 EKX53833.1 - 0.12 12.3 7.6 0.086 12.8 0.2 3.8 5 0 0 5 5 5 0 Zinc-binding dehydrogenase NAD_binding_8 PF13450.6 EKX53833.1 - 0.16 12.2 0.8 0.96 9.7 0.2 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain TFIID-31kDa PF02291.15 EKX53834.1 - 1.3e-24 86.6 0.0 1.4e-24 86.5 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Phage_P2_GpU PF06995.11 EKX53834.1 - 0.032 13.9 0.0 0.043 13.4 0.0 1.1 1 0 0 1 1 1 0 Phage P2 GpU 60KD_IMP PF02096.20 EKX53835.1 - 9.5e-17 61.4 0.1 1.3e-16 61.0 0.1 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein HA PF03457.14 EKX53837.1 - 1.2e-29 102.5 10.7 4.7e-17 62.1 1.6 2.1 2 0 0 2 2 2 2 Helicase associated domain DUF4817 PF16087.5 EKX53837.1 - 0.038 13.8 0.1 8.5 6.3 0.0 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain (DUF4817) Laminin_G_3 PF13385.6 EKX53838.1 - 4.8e-08 33.3 0.0 4.8e-08 33.3 0.0 2.9 4 0 0 4 4 4 1 Concanavalin A-like lectin/glucanases superfamily PAN_3 PF08277.12 EKX53838.1 - 0.33 10.8 5.2 1 9.2 4.8 2.2 1 1 0 1 1 1 0 PAN-like domain PAN_4 PF14295.6 EKX53838.1 - 0.63 10.0 14.4 0.13 12.2 4.2 3.7 3 1 0 3 3 3 0 PAN domain PAN_2 PF08276.11 EKX53838.1 - 0.81 9.9 7.2 0.22 11.7 2.6 2.5 2 0 0 2 2 2 0 PAN-like domain DZR PF12773.7 EKX53839.1 - 1.2e-05 25.2 0.6 2.2e-05 24.4 0.6 1.4 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 EKX53839.1 - 0.00024 20.7 4.9 0.00045 19.8 4.9 1.5 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_15 PF17032.5 EKX53839.1 - 0.0008 20.1 0.4 0.0012 19.5 0.4 1.3 1 0 0 1 1 1 1 zinc-ribbon family UPF0547 PF10571.9 EKX53839.1 - 0.0038 17.3 3.8 0.01 15.9 3.8 1.7 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 zf-NADH-PPase PF09297.11 EKX53839.1 - 0.0062 16.2 1.6 0.0062 16.2 1.6 2.0 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.6 EKX53839.1 - 0.0089 15.4 4.0 0.028 13.8 4.0 1.9 1 1 0 1 1 1 1 zinc-ribbon domain GFA PF04828.14 EKX53839.1 - 0.028 14.7 0.5 3 8.2 0.2 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 EKX53839.1 - 0.13 12.2 0.4 0.13 12.2 0.4 3.2 3 0 0 3 3 3 0 Nudix N-terminal Auto_anti-p27 PF06677.12 EKX53839.1 - 0.16 12.2 1.7 0.38 10.9 1.7 1.7 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) HypA PF01155.19 EKX53839.1 - 0.19 11.8 0.3 0.31 11.1 0.3 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Prok-RING_1 PF14446.6 EKX53839.1 - 0.24 11.3 4.7 0.58 10.1 4.7 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 NOB1_Zn_bind PF08772.11 EKX53839.1 - 0.25 11.5 2.2 0.52 10.5 2.2 1.5 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like IQ PF00612.27 EKX53840.1 - 1.1e-08 34.1 14.7 0.0029 17.3 0.5 3.9 4 0 0 4 4 4 3 IQ calmodulin-binding motif BBS2_N PF14781.6 EKX53840.1 - 0.18 11.7 0.8 0.37 10.7 0.0 1.9 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal APC_u15 PF16636.5 EKX53840.1 - 2.5 8.6 7.2 0.24 11.9 1.1 2.2 2 0 0 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 CCDC-167 PF15188.6 EKX53840.1 - 6.9 7.1 9.8 0.13 12.6 2.0 2.1 3 1 0 3 3 3 0 Coiled-coil domain-containing protein 167 Romo1 PF10247.9 EKX53841.1 - 0.86 10.0 6.7 0.15 12.4 0.8 2.1 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 CNRIP1 PF15043.6 EKX53842.1 - 1.3e-11 44.3 0.1 1.9e-11 43.7 0.1 1.2 1 0 0 1 1 1 1 CB1 cannabinoid receptor-interacting protein 1 MiaE_2 PF13794.6 EKX53842.1 - 0.021 14.6 0.0 0.036 13.8 0.0 1.4 2 0 0 2 2 2 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like Ephrin_rec_like PF07699.13 EKX53843.1 - 1.2e-19 69.8 54.1 5.5e-06 26.0 8.4 7.6 4 3 4 8 8 8 6 Putative ephrin-receptor like Furin-like_2 PF15913.5 EKX53843.1 - 0.00011 22.3 5.5 0.00011 22.3 5.5 3.8 1 1 3 4 4 4 1 Furin-like repeat, cysteine-rich TNFR_c6 PF00020.18 EKX53843.1 - 0.0086 16.5 38.5 0.27 11.7 0.5 8.0 2 2 4 7 7 7 4 TNFR/NGFR cysteine-rich region cEGF PF12662.7 EKX53843.1 - 0.021 14.8 0.2 0.021 14.8 0.2 8.3 8 1 1 9 9 9 0 Complement Clr-like EGF-like HEAT_2 PF13646.6 EKX53844.1 - 4.2e-34 116.8 19.9 4.4e-16 59.0 1.5 3.1 2 1 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.16 EKX53844.1 - 1.1e-17 62.9 10.5 0.0015 19.0 0.1 6.8 7 0 0 7 7 7 4 PBS lyase HEAT-like repeat HEAT PF02985.22 EKX53844.1 - 4.7e-13 48.2 6.4 0.0012 18.9 0.0 6.2 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 EKX53844.1 - 3.5e-08 33.8 10.9 0.0063 17.0 0.0 5.5 6 1 0 6 6 6 3 HEAT-like repeat Arm PF00514.23 EKX53844.1 - 0.00014 21.7 2.6 0.035 14.2 0.0 3.5 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat DUF2019 PF09450.10 EKX53844.1 - 0.0042 17.0 1.0 1.5 8.8 0.3 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF2019) hnRNP_Q_AcD PF18360.1 EKX53844.1 - 0.074 13.0 2.1 0.19 11.7 0.0 2.6 3 0 0 3 3 3 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain DUF3385 PF11865.8 EKX53844.1 - 0.08 12.9 0.0 0.86 9.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) S-methyl_trans PF02574.16 EKX53845.1 - 6.7e-32 111.3 0.0 1.1e-31 110.6 0.0 1.3 1 1 0 1 1 1 1 Homocysteine S-methyltransferase DUF2256 PF10013.9 EKX53845.1 - 0.15 12.2 0.1 0.29 11.3 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) Glyco_transf_41 PF13844.6 EKX53846.1 - 3.2e-81 273.1 0.0 4.4e-47 160.6 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_1 PF00515.28 EKX53846.1 - 5.4e-32 108.3 13.3 3.5e-06 26.6 0.1 8.0 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 EKX53846.1 - 1.1e-28 98.7 6.6 0.00099 18.7 0.3 7.7 1 1 6 7 7 7 7 TPR repeat TPR_8 PF13181.6 EKX53846.1 - 2.1e-28 96.1 8.1 0.00028 20.9 0.0 7.8 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 EKX53846.1 - 1.4e-26 90.4 10.6 6.2e-06 25.9 0.1 7.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 EKX53846.1 - 2.6e-18 65.0 9.6 0.025 14.9 0.0 8.1 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 EKX53846.1 - 1e-15 57.8 17.4 4.5e-05 23.7 0.1 6.3 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.6 EKX53846.1 - 1.1e-10 41.4 10.4 0.0089 16.8 0.0 7.5 2 1 6 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX53846.1 - 4.5e-10 40.0 15.8 0.0092 16.6 1.7 4.8 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 EKX53846.1 - 6.1e-10 38.4 5.1 0.0012 18.8 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX53846.1 - 4.4e-08 33.5 6.9 0.005 17.3 0.2 3.7 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX53846.1 - 3.4e-07 29.9 26.0 0.017 15.0 0.1 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 EKX53846.1 - 4e-05 23.7 0.6 1.3 9.3 0.0 4.0 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 EKX53846.1 - 0.00055 19.2 2.1 0.59 9.3 0.0 2.5 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_4 PF07721.14 EKX53846.1 - 0.005 17.3 0.2 17 6.4 0.0 4.6 4 0 0 4 4 3 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 EKX53846.1 - 0.0064 16.4 0.7 0.016 15.1 0.1 2.0 2 0 0 2 2 2 1 Virulence factor membrane-bound polymerase, C-terminal TPR_6 PF13174.6 EKX53846.1 - 0.0098 16.5 14.7 13 6.7 0.1 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat RPN7 PF10602.9 EKX53846.1 - 0.014 15.1 0.1 0.12 12.0 0.0 2.5 2 0 0 2 2 2 0 26S proteasome subunit RPN7 HemY_N PF07219.13 EKX53846.1 - 0.39 10.9 1.9 1.6 9.0 0.4 2.7 2 0 0 2 2 2 0 HemY protein N-terminus PAS_9 PF13426.7 EKX53847.1 - 2.2e-13 50.3 0.0 1.9e-08 34.5 0.0 2.7 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 EKX53847.1 - 6.5e-07 29.3 0.0 7e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 EKX53847.1 - 7.5e-05 22.9 0.0 0.00023 21.4 0.0 1.8 1 1 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EKX53847.1 - 0.00071 19.5 0.0 1.7 8.7 0.0 2.5 2 0 0 2 2 2 2 PAS domain Pox_E10 PF04805.12 EKX53847.1 - 0.11 12.4 0.5 6 6.8 0.5 2.5 2 0 0 2 2 2 0 E10-like protein conserved region Ank_5 PF13857.6 EKX53848.1 - 1.8e-17 63.2 3.5 9.6e-11 41.7 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX53848.1 - 1e-13 51.0 0.8 8.2e-10 38.7 0.2 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EKX53848.1 - 1.2e-13 51.2 0.3 2.7e-07 31.0 0.2 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX53848.1 - 3.3e-13 50.0 0.1 4e-12 46.5 0.1 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX53848.1 - 6.4e-11 41.5 0.0 1.1e-06 28.5 0.0 2.5 3 0 0 3 3 3 2 Ankyrin repeat DUF655 PF04919.12 EKX53848.1 - 0.19 11.7 0.0 0.19 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF655) RWP-RK PF02042.15 EKX53850.1 - 1e-16 60.6 0.0 1.8e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX53850.1 - 0.0055 16.5 0.3 0.11 12.3 0.1 2.3 1 1 1 2 2 2 1 Bacterial regulatory protein, Fis family Shisa PF13908.6 EKX53851.1 - 0.086 13.1 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4834 PF16118.5 EKX53851.1 - 0.14 13.1 0.7 0.32 12.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) LysM PF01476.20 EKX53852.1 - 2e-10 40.5 0.1 3.6e-05 23.7 0.1 2.4 2 0 0 2 2 2 2 LysM domain Inhibitor_I34 PF10466.9 EKX53853.1 - 0.015 15.9 0.1 0.18 12.5 0.0 2.5 2 0 0 2 2 2 0 Saccharopepsin inhibitor I34 ATP_synth_reg PF14960.6 EKX53853.1 - 0.045 13.2 0.0 0.34 10.4 0.0 2.1 2 0 0 2 2 2 0 ATP synthase regulation RWP-RK PF02042.15 EKX53854.1 - 1.5e-15 56.9 0.0 2.3e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain Sigma70_r4_2 PF08281.12 EKX53854.1 - 0.0065 16.1 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_17 PF12728.7 EKX53854.1 - 0.2 11.9 0.0 0.55 10.5 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain RWP-RK PF02042.15 EKX53855.1 - 2.1e-15 56.4 0.0 3.7e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain Sigma70_r4_2 PF08281.12 EKX53855.1 - 0.0095 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 RWP-RK PF02042.15 EKX53856.1 - 2.1e-15 56.4 0.0 3.5e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain Sigma70_r4_2 PF08281.12 EKX53856.1 - 0.0079 15.8 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Fungal_trans PF04082.18 EKX53856.1 - 0.088 11.8 0.2 0.49 9.4 0.2 1.9 1 1 0 1 1 1 0 Fungal specific transcription factor domain Qn_am_d_aII PF14930.6 EKX53857.1 - 0.025 14.9 0.1 0.055 13.8 0.1 1.5 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II SGTA_dimer PF16546.5 EKX53857.1 - 0.12 12.2 0.1 0.35 10.7 0.0 1.8 2 0 0 2 2 2 0 Homodimerisation domain of SGTA ALIX_LYPXL_bnd PF13949.6 EKX53858.1 - 0.13 11.5 1.2 0.23 10.7 0.7 1.5 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV CP_ATPgrasp_2 PF14403.6 EKX53859.1 - 0.0064 15.5 0.0 0.008 15.1 0.0 1.2 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 YkuI_C PF10388.9 EKX53861.1 - 0.12 12.1 0.2 0.12 12.1 0.2 2.3 2 1 0 2 2 2 0 EAL-domain associated signalling protein domain COesterase PF00135.28 EKX53861.1 - 2.7 6.7 7.1 0.52 9.1 2.9 1.7 1 1 1 2 2 2 0 Carboxylesterase family CactinC_cactus PF09732.9 EKX53862.1 - 5.4e-59 197.6 9.6 1.1e-58 196.6 9.6 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 EKX53862.1 - 1.3e-54 184.9 8.6 1.3e-54 184.9 8.6 2.9 3 1 0 3 3 3 1 Conserved mid region of cactin PDZ_2 PF13180.6 EKX53863.1 - 3.7e-10 40.0 0.3 6.7e-10 39.2 0.3 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX53863.1 - 5.7e-07 29.8 0.3 1.3e-06 28.6 0.3 1.7 1 1 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX53863.1 - 3e-06 27.0 0.3 5.3e-06 26.2 0.3 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX53863.1 - 0.024 14.6 0.3 0.074 13.0 0.1 1.9 2 0 0 2 2 2 0 Tricorn protease PDZ domain RusA PF05866.11 EKX53863.1 - 0.062 13.8 0.0 0.094 13.3 0.0 1.3 1 0 0 1 1 1 0 Endodeoxyribonuclease RusA SlyX PF04102.12 EKX53863.1 - 0.095 13.3 2.0 1.9 9.2 0.1 2.3 2 0 0 2 2 2 0 SlyX PDEase_I PF00233.19 EKX53864.1 - 7e-53 179.8 0.2 1.2e-52 179.0 0.2 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Myb_DNA-binding PF00249.31 EKX53865.1 - 1.1e-07 31.9 1.5 1.1e-07 31.9 1.5 2.4 2 1 0 2 2 2 1 Myb-like DNA-binding domain TEA PF01285.18 EKX53865.1 - 0.0045 17.0 0.3 0.021 14.9 0.3 2.1 1 1 0 1 1 1 1 TEA/ATTS domain PDZ_6 PF17820.1 EKX53866.1 - 2e-26 91.6 3.3 3.6e-09 36.3 0.0 3.5 3 0 0 3 3 3 3 PDZ domain PDZ PF00595.24 EKX53866.1 - 5.1e-26 90.8 11.9 1.7e-09 37.9 1.2 3.9 4 0 0 4 4 4 3 PDZ domain PDZ_2 PF13180.6 EKX53866.1 - 3e-24 85.1 1.2 3.6e-10 40.0 0.0 3.4 3 0 0 3 3 3 3 PDZ domain UBA PF00627.31 EKX53866.1 - 3e-19 68.5 0.0 5.7e-12 45.3 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain Tricorn_PDZ PF14685.6 EKX53866.1 - 1.8e-06 27.8 3.6 0.22 11.5 0.2 4.4 3 2 0 3 3 3 2 Tricorn protease PDZ domain GRASP55_65 PF04495.14 EKX53866.1 - 0.00059 20.2 0.2 0.5 10.7 0.1 2.7 2 1 0 2 2 2 2 GRASP55/65 PDZ-like domain UBA_3 PF09288.10 EKX53866.1 - 0.0033 17.2 0.0 0.35 10.7 0.0 2.6 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain RuvA_C PF07499.13 EKX53866.1 - 0.019 15.4 0.0 0.16 12.4 0.0 2.4 2 0 0 2 2 2 0 RuvA, C-terminal domain Rap1_C PF11626.8 EKX53866.1 - 0.038 14.1 0.0 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain TetR_C_1 PF02909.17 EKX53866.1 - 0.15 11.9 0.1 0.8 9.5 0.0 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF4064 PF13273.6 EKX53867.1 - 0.00041 20.6 0.3 0.03 14.6 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF4064) LAB_N PF07578.11 EKX53867.1 - 0.043 13.9 0.3 5.2 7.2 0.4 2.7 2 0 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain PsbX PF06596.11 EKX53867.1 - 0.33 11.0 2.3 0.96 9.5 2.3 1.8 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) ADK_lid PF05191.14 EKX53867.1 - 1 9.4 4.3 2.4 8.2 4.3 1.6 1 0 0 1 1 1 0 Adenylate kinase, active site lid 2-Hacid_dh_C PF02826.19 EKX53868.1 - 2e-27 95.7 1.2 3.7e-16 59.0 0.1 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EKX53868.1 - 1.4e-10 41.0 0.0 2.8e-07 30.3 0.0 2.0 1 1 1 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EKX53868.1 - 0.028 14.6 0.1 0.067 13.4 0.1 1.7 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Gp_dh_N PF00044.24 EKX53868.1 - 0.046 14.1 0.2 0.13 12.6 0.2 1.8 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EKX53868.1 - 0.11 12.6 0.1 0.36 10.9 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase TPR_12 PF13424.6 EKX53869.1 - 2.8e-05 24.3 1.5 0.0048 17.2 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX53869.1 - 0.00092 19.2 0.9 0.78 10.1 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat Adenyl_transf PF04439.12 EKX53869.1 - 0.048 12.8 0.0 0.86 8.7 0.0 2.1 2 0 0 2 2 2 0 Streptomycin adenylyltransferase TPR_MalT PF17874.1 EKX53869.1 - 0.069 12.5 2.1 0.18 11.1 0.1 2.3 2 1 1 3 3 3 0 MalT-like TPR region TPR_6 PF13174.6 EKX53869.1 - 0.13 12.9 0.0 44 5.0 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF561 PF04481.12 EKX53870.1 - 4e-85 284.9 1.1 4.5e-85 284.7 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF561) NMO PF03060.15 EKX53870.1 - 0.00032 20.2 4.9 0.00032 20.2 4.9 1.7 2 0 0 2 2 2 1 Nitronate monooxygenase TMP-TENI PF02581.17 EKX53870.1 - 0.0029 17.0 5.6 0.023 14.0 2.8 2.7 3 1 0 3 3 3 1 Thiamine monophosphate synthase Pterin_bind PF00809.22 EKX53870.1 - 1.2 8.7 7.0 9.4 5.8 1.4 3.5 2 2 1 3 3 3 0 Pterin binding enzyme 3Beta_HSD PF01073.19 EKX53872.1 - 1.8e-10 40.3 0.1 0.00037 19.6 0.0 2.2 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EKX53872.1 - 2.5e-10 40.3 0.0 1.1e-09 38.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EKX53872.1 - 6.6e-08 32.4 0.0 9.8e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 EKX53872.1 - 4.5e-07 29.2 0.0 1.4e-05 24.4 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EKX53872.1 - 2.4e-06 27.6 0.0 4.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EKX53872.1 - 0.00074 18.8 0.1 0.25 10.5 0.0 2.7 2 1 1 3 3 3 2 Male sterility protein Sacchrp_dh_NADP PF03435.18 EKX53872.1 - 0.056 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain EIIBC-GUT_N PF03612.14 EKX53874.1 - 0.049 13.4 2.5 0.076 12.8 2.5 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CobT PF06213.12 EKX53874.1 - 0.11 11.9 9.0 0.17 11.2 9.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DDHD PF02862.17 EKX53874.1 - 0.16 12.1 1.7 0.21 11.7 1.7 1.2 1 0 0 1 1 1 0 DDHD domain DUF4175 PF13779.6 EKX53874.1 - 0.17 9.7 7.3 0.22 9.4 7.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FAM150 PF15129.6 EKX53874.1 - 0.25 11.5 4.0 0.54 10.4 4.0 1.5 1 0 0 1 1 1 0 FAM150 family Connexin PF00029.19 EKX53874.1 - 0.29 10.9 4.3 1.4 8.6 5.0 1.7 2 0 0 2 2 2 0 Connexin Presenilin PF01080.17 EKX53874.1 - 0.63 8.7 4.0 0.75 8.5 4.0 1.1 1 0 0 1 1 1 0 Presenilin Atrophin-1 PF03154.15 EKX53874.1 - 2.4 6.3 9.5 3.3 5.9 9.5 1.1 1 0 0 1 1 1 0 Atrophin-1 family Ion_trans PF00520.31 EKX53875.1 - 2.2e-113 377.5 55.7 1.3e-40 139.2 2.8 5.2 5 0 0 5 5 5 5 Ion transport protein EF-hand_7 PF13499.6 EKX53875.1 - 2.9e-13 50.1 5.4 1.1e-10 41.8 0.3 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX53875.1 - 6e-12 44.5 4.6 1.9e-05 24.2 0.3 3.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EKX53875.1 - 8.2e-12 43.8 6.1 6.8e-06 25.3 0.3 3.6 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 EKX53875.1 - 4.5e-07 29.1 6.7 0.00031 20.1 0.3 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EKX53875.1 - 1.3e-06 28.1 7.0 6e-06 26.0 0.3 3.4 2 1 1 3 3 3 1 EF-hand domain pair PKD_channel PF08016.12 EKX53875.1 - 0.018 13.7 46.2 0.055 12.1 0.6 6.0 5 1 1 6 6 6 0 Polycystin cation channel Adenine_glyco PF03352.13 EKX53875.1 - 0.036 13.9 0.3 0.17 11.6 0.1 2.2 2 0 0 2 2 2 0 Methyladenine glycosylase EF-hand_4 PF12763.7 EKX53875.1 - 0.37 10.8 4.6 0.56 10.2 0.1 2.9 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand PTCB-BRCT PF12738.7 EKX53876.1 - 3e-29 100.8 0.1 4.2e-10 39.4 0.0 5.6 5 1 0 5 5 5 3 twin BRCT domain BRCT PF00533.26 EKX53876.1 - 2.4e-28 98.3 1.6 8.4e-07 29.3 0.0 6.5 6 1 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EKX53876.1 - 5.8e-22 77.9 0.2 1.6e-05 25.2 0.2 5.6 4 1 1 5 5 5 5 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 EKX53876.1 - 1.8e-05 24.7 0.7 6 7.0 0.0 4.1 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EKX53876.1 - 0.37 11.1 4.5 7.1 7.0 0.0 4.2 5 1 0 5 5 5 0 DNA ligase 3 BRCT domain HEAT_2 PF13646.6 EKX53877.1 - 8.3e-08 32.5 10.4 0.00035 20.9 0.1 5.7 5 2 0 5 5 5 2 HEAT repeats HEAT PF02985.22 EKX53877.1 - 1.4e-07 31.1 2.3 0.00013 21.9 0.0 5.2 6 0 0 6 6 6 1 HEAT repeat Vac14_Fab1_bd PF12755.7 EKX53877.1 - 1.4e-06 28.8 0.5 0.028 15.0 0.0 3.3 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EKX53877.1 - 0.0026 17.3 0.2 0.16 11.5 0.1 2.3 2 0 0 2 2 2 1 CLASP N terminal HEAT_EZ PF13513.6 EKX53877.1 - 0.12 12.9 1.7 2.7 8.6 0.1 3.3 2 0 0 2 2 2 0 HEAT-like repeat Cnd1 PF12717.7 EKX53877.1 - 0.16 12.0 4.6 0.13 12.3 0.3 2.8 2 2 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 DUF2935 PF11155.8 EKX53878.1 - 0.0037 17.6 5.1 0.0077 16.6 1.5 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF2935) Latarcin PF10279.9 EKX53878.1 - 0.082 13.3 0.0 0.082 13.3 0.0 3.1 3 1 1 4 4 4 0 Latarcin precursor MerR-DNA-bind PF09278.11 EKX53878.1 - 1.6 9.4 15.1 0.057 14.0 5.2 3.8 4 0 0 4 4 4 0 MerR, DNA binding DUF1664 PF07889.12 EKX53878.1 - 8.1 6.5 18.2 9.2 6.3 3.2 4.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) LRR_4 PF12799.7 EKX53879.1 - 5.7e-05 23.4 0.1 0.0013 19.1 0.1 2.1 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX53879.1 - 0.0012 18.5 0.7 0.0035 17.1 0.6 1.8 1 1 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.33 EKX53879.1 - 0.0062 16.9 0.0 1.9 9.4 0.0 3.1 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.6 EKX53879.1 - 0.019 15.0 0.4 2.8 8.2 0.0 3.1 3 0 0 3 3 3 0 Leucine Rich repeat DUF3338 PF11819.8 EKX53879.1 - 0.049 13.6 0.1 0.077 13.0 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3338) Guanylate_cyc PF00211.20 EKX53880.1 - 3e-09 36.8 0.0 3.8e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PGK PF00162.19 EKX53881.1 - 2.7e-144 480.8 0.0 3.1e-144 480.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 EKX53881.1 - 0.07 13.2 0.0 0.25 11.4 0.0 2.0 1 1 0 1 1 1 0 PA domain Guanylate_cyc PF00211.20 EKX53882.1 - 3e-09 36.8 0.0 3.8e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_4 PF12799.7 EKX53883.1 - 0.0004 20.7 0.1 0.0093 16.4 0.0 2.1 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) BCL9 PF11502.8 EKX53883.1 - 0.0068 16.2 0.7 0.0099 15.7 0.7 1.3 1 0 0 1 1 1 1 B-cell lymphoma 9 protein LRR_8 PF13855.6 EKX53883.1 - 0.018 14.8 1.3 0.067 13.0 0.7 1.8 1 1 0 1 1 1 0 Leucine rich repeat LRR_1 PF00560.33 EKX53883.1 - 0.05 14.1 0.0 2.5 9.0 0.0 2.8 3 0 0 3 3 3 0 Leucine Rich Repeat DUF3338 PF11819.8 EKX53883.1 - 0.11 12.5 0.1 0.18 11.8 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3338) OKR_DC_1_C PF03711.15 EKX53884.1 - 2.8e-09 37.4 0.0 5.5e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, C-terminal domain FHA PF00498.26 EKX53885.1 - 7.6e-15 55.0 0.0 1.5e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EKX53885.1 - 3.4e-10 40.1 0.1 1.7e-09 37.9 0.1 2.1 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain F-box PF00646.33 EKX53885.1 - 0.049 13.5 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 F-box domain EF-hand_1 PF00036.32 EKX53886.1 - 3.8e-12 44.8 1.0 0.00029 20.1 0.1 3.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EKX53886.1 - 2.9e-11 42.3 5.0 0.00044 20.0 0.1 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 EKX53886.1 - 1.3e-08 35.2 4.7 0.0069 16.8 0.1 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EKX53886.1 - 2.4e-07 29.9 6.8 0.0094 15.4 0.1 4.3 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 EKX53886.1 - 6.9e-05 22.6 0.6 0.36 10.7 0.0 2.9 2 2 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX53886.1 - 0.045 14.1 0.4 0.23 11.8 0.2 2.1 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region S_100 PF01023.19 EKX53886.1 - 0.049 13.3 0.4 1.2 8.9 0.0 2.9 3 0 0 3 3 3 0 S-100/ICaBP type calcium binding domain Staphylokinase PF02821.16 EKX53886.1 - 0.14 12.6 1.8 0.68 10.4 0.4 2.1 1 1 0 2 2 2 0 Staphylokinase/Streptokinase family Pkinase PF00069.25 EKX53887.1 - 9.3e-26 90.7 0.0 1.5e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX53887.1 - 1.5e-10 40.8 0.0 2.2e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX53887.1 - 0.058 12.7 0.0 0.25 10.7 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EKX53887.1 - 0.19 11.3 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase FHA PF00498.26 EKX53888.1 - 8.1e-06 26.1 0.0 2.3e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EKX53888.1 - 0.056 13.8 0.1 0.35 11.2 0.0 2.3 2 1 1 3 3 3 0 Inner membrane component of T3SS, cytoplasmic domain DUF3138 PF11336.8 EKX53888.1 - 0.18 10.4 4.7 0.27 9.8 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Sds3 PF08598.11 EKX53888.1 - 0.21 11.6 9.2 2.6 8.0 0.5 3.2 2 1 1 3 3 3 0 Sds3-like CagE_TrbE_VirB PF03135.14 EKX53888.1 - 0.29 11.2 3.6 0.41 10.7 3.6 1.3 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system Ribosomal_60s PF00428.19 EKX53888.1 - 4 8.1 15.5 9.2 6.9 15.5 1.6 1 1 0 1 1 1 0 60s Acidic ribosomal protein Herpes_BLRF2 PF05812.12 EKX53888.1 - 4.7 7.4 10.5 0.89 9.7 2.4 2.4 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein DSPc PF00782.20 EKX53889.1 - 1.8e-26 92.5 0.0 2.7e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain FHA PF00498.26 EKX53889.1 - 1.8e-21 76.2 1.3 7.5e-20 71.1 0.0 2.9 2 1 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EKX53889.1 - 2.9e-12 46.7 0.3 1e-11 45.0 0.1 2.0 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 EKX53889.1 - 2.8e-06 27.5 0.0 5.6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain Rhodanese PF00581.20 EKX53889.1 - 0.0003 21.3 0.0 0.0086 16.6 0.0 3.1 3 1 1 4 4 4 1 Rhodanese-like domain Y_phosphatase PF00102.27 EKX53889.1 - 0.0099 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Alg14 PF08660.11 EKX53890.1 - 3.6e-58 196.3 0.0 4.3e-58 196.1 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like PARP PF00644.20 EKX53891.1 - 8.2e-13 48.4 0.0 3e-12 46.6 0.0 2.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PH_6 PF15406.6 EKX53891.1 - 0.028 14.7 0.0 0.1 12.9 0.0 1.9 1 1 1 2 2 2 0 Pleckstrin homology domain Intein_splicing PF14890.6 EKX53891.1 - 0.06 13.3 0.1 0.11 12.5 0.1 1.6 1 1 0 1 1 1 0 Intein splicing domain Pkinase PF00069.25 EKX53892.1 - 2.5e-53 181.1 0.1 4.6e-53 180.3 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX53892.1 - 2.2e-34 118.9 0.1 3.4e-34 118.3 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EKX53892.1 - 0.013 14.8 0.1 0.027 13.8 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EKX53892.1 - 0.04 13.2 0.0 0.089 12.1 0.0 1.5 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 EKX53892.1 - 0.23 11.4 1.1 6.3 6.6 0.1 2.7 2 1 0 3 3 3 0 Phosphotransferase enzyme family HA2 PF04408.23 EKX53895.1 - 5.1e-20 71.8 3.9 1.2e-19 70.6 0.0 2.9 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EKX53895.1 - 2.2e-15 56.8 0.0 5e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EKX53895.1 - 2e-13 50.6 0.0 7.2e-13 48.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EKX53895.1 - 2.2e-07 30.8 0.2 5.5e-07 29.5 0.2 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EKX53895.1 - 1.6e-06 28.4 0.1 5.4e-06 26.7 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EKX53895.1 - 0.00072 19.3 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EKX53895.1 - 0.00085 19.4 0.1 1.6 8.7 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EKX53895.1 - 0.0016 18.8 0.1 0.0075 16.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EKX53895.1 - 0.0027 17.0 0.0 0.0059 15.9 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 EKX53895.1 - 0.0031 17.3 0.0 0.007 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EKX53895.1 - 0.0057 15.7 0.1 0.017 14.2 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 EKX53895.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain ATPase PF06745.13 EKX53895.1 - 0.039 13.3 0.0 0.087 12.2 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.6 EKX53895.1 - 0.042 13.9 0.5 0.5 10.4 0.2 2.6 2 1 0 2 2 2 0 AAA domain Microtub_bd PF16796.5 EKX53895.1 - 0.045 13.7 0.2 0.11 12.4 0.2 1.6 1 0 0 1 1 1 0 Microtubule binding AAA_7 PF12775.7 EKX53895.1 - 0.046 13.2 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SRP54 PF00448.22 EKX53895.1 - 0.089 12.4 0.2 0.17 11.5 0.2 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 EKX53895.1 - 0.11 12.2 0.0 5 6.8 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 EKX53895.1 - 0.14 11.9 0.0 0.48 10.1 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Amidase PF01425.21 EKX53895.1 - 0.14 11.1 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Amidase Atrophin-1 PF03154.15 EKX53895.1 - 2.9 6.1 22.2 4.5 5.4 22.2 1.2 1 0 0 1 1 1 0 Atrophin-1 family DUF3915 PF13054.6 EKX53895.1 - 7.3 6.6 15.5 36 4.3 15.5 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Adaptin_N PF01602.20 EKX53898.1 - 1.4e-105 353.9 4.9 1.7e-105 353.6 4.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 EKX53898.1 - 3.8e-18 65.7 0.0 1.2e-17 64.1 0.0 1.9 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Cnd1 PF12717.7 EKX53898.1 - 2.3e-10 40.7 0.6 2.2e-07 31.0 0.0 3.6 1 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Alpha_adaptinC2 PF02883.20 EKX53898.1 - 1.3e-09 38.3 1.9 2.9e-09 37.2 1.9 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.6 EKX53898.1 - 3.6e-05 24.1 0.2 0.013 15.8 0.0 3.8 3 1 0 3 3 3 1 HEAT repeats Leader_CPA1 PF08252.11 EKX53898.1 - 0.032 13.6 0.3 0.065 12.6 0.3 1.5 1 0 0 1 1 1 0 arg-2/CPA1 leader peptide HEAT PF02985.22 EKX53898.1 - 0.095 13.0 0.5 16 6.1 0.0 3.7 4 0 0 4 4 4 0 HEAT repeat GP44 PF17510.2 EKX53898.1 - 0.11 12.7 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 Gene product 44 DctQ PF04290.12 EKX53898.1 - 0.15 12.0 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component AAR2 PF05282.11 EKX53898.1 - 1.6 8.1 5.3 2 7.7 0.6 2.7 2 1 1 3 3 3 0 AAR2 protein ALAD PF00490.21 EKX53899.1 - 1.5e-130 435.0 0.0 1.9e-130 434.7 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase CnrY PF17524.2 EKX53899.1 - 0.11 12.7 0.4 0.32 11.3 0.4 1.8 1 0 0 1 1 1 0 Anti-sigma factor CnrY Herpes_BLLF1 PF05109.13 EKX53902.1 - 0.2 9.6 5.5 0.23 9.4 5.5 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) AOX PF01786.17 EKX53904.1 - 1.7e-92 308.9 0.6 1.9e-92 308.7 0.6 1.0 1 0 0 1 1 1 1 Alternative oxidase AOX PF01786.17 EKX53905.1 - 1.6e-91 305.7 0.3 1.9e-91 305.4 0.3 1.1 1 0 0 1 1 1 1 Alternative oxidase AOX PF01786.17 EKX53906.1 - 1e-91 306.3 0.3 1.2e-91 306.1 0.3 1.0 1 0 0 1 1 1 1 Alternative oxidase Prenyltrans PF00432.21 EKX53907.1 - 0.0054 16.4 0.0 0.0094 15.7 0.0 1.4 1 0 0 1 1 1 1 Prenyltransferase and squalene oxidase repeat RNA_pol_Rpc4 PF05132.14 EKX53908.1 - 0.0012 19.3 3.8 0.0015 18.9 3.8 1.2 1 0 0 1 1 1 1 RNA polymerase III RPC4 DDHD PF02862.17 EKX53908.1 - 0.0012 19.1 5.0 0.0015 18.7 5.0 1.1 1 0 0 1 1 1 1 DDHD domain AIF_C PF14721.6 EKX53908.1 - 0.0029 17.9 6.5 0.024 15.0 7.3 1.8 2 0 0 2 2 2 1 Apoptosis-inducing factor, mitochondrion-associated, C-term eIF-3_zeta PF05091.12 EKX53908.1 - 0.0032 16.5 10.3 0.0043 16.1 10.3 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur_chan_memb PF02932.16 EKX53908.1 - 0.0046 17.1 0.6 0.005 16.9 0.6 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF3408 PF11888.8 EKX53908.1 - 0.0064 16.6 10.5 0.015 15.5 10.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3408) DUF913 PF06025.12 EKX53908.1 - 0.011 14.7 4.1 0.019 14.0 4.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 EKX53908.1 - 0.013 15.4 11.5 0.019 14.8 11.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tenui_NCP PF04876.12 EKX53908.1 - 0.013 15.1 0.0 0.029 13.9 0.0 1.5 2 0 0 2 2 1 0 Tenuivirus major non-capsid protein DUF1980 PF09323.10 EKX53908.1 - 0.014 15.3 4.2 0.022 14.7 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) CCDC53 PF10152.9 EKX53908.1 - 0.016 15.6 11.3 0.026 14.9 11.3 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Baculo_PP31 PF05311.11 EKX53908.1 - 0.018 14.5 7.3 0.025 14.0 7.3 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) FAM91_C PF14648.6 EKX53908.1 - 0.022 13.6 3.1 0.028 13.3 3.1 1.1 1 0 0 1 1 1 0 FAM91 C-terminus Pex14_N PF04695.13 EKX53908.1 - 0.029 15.1 10.5 0.049 14.3 10.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 EKX53908.1 - 0.031 13.1 9.7 0.037 12.8 9.7 1.1 1 0 0 1 1 1 0 Presenilin Paf1 PF03985.13 EKX53908.1 - 0.031 13.3 10.6 0.04 12.9 10.6 1.2 1 0 0 1 1 1 0 Paf1 Connexin PF00029.19 EKX53908.1 - 0.038 13.8 8.7 0.056 13.2 8.7 1.2 1 0 0 1 1 1 0 Connexin EIIBC-GUT_N PF03612.14 EKX53908.1 - 0.067 12.9 10.9 0.61 9.8 10.8 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus EOS1 PF12326.8 EKX53908.1 - 0.074 13.0 3.1 0.11 12.4 3.1 1.3 1 0 0 1 1 1 0 N-glycosylation protein DUF4050 PF13259.6 EKX53908.1 - 0.077 13.3 7.5 0.72 10.2 5.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) Ferlin_C PF16165.5 EKX53908.1 - 0.079 12.9 2.5 0.14 12.0 2.5 1.4 1 0 0 1 1 1 0 Ferlin C-terminus DUF2828 PF11443.8 EKX53908.1 - 0.086 10.9 11.6 0.14 10.2 11.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SID-1_RNA_chan PF13965.6 EKX53908.1 - 0.11 10.9 0.4 0.11 10.8 0.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4834 PF16118.5 EKX53908.1 - 0.13 13.2 14.3 0.27 12.2 14.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF4407 PF14362.6 EKX53908.1 - 0.19 11.1 13.0 0.25 10.6 13.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TERB2 PF15101.6 EKX53908.1 - 0.21 11.6 15.0 0.47 10.5 15.0 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Tim54 PF11711.8 EKX53908.1 - 0.23 10.2 12.3 0.36 9.6 12.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SLC12 PF03522.15 EKX53908.1 - 0.32 10.0 10.9 0.45 9.5 10.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF3807 PF12720.7 EKX53908.1 - 0.33 11.2 19.5 0.52 10.6 19.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) CBP_BcsG PF11658.8 EKX53908.1 - 0.34 9.2 7.6 0.53 8.6 7.6 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG Serinc PF03348.15 EKX53908.1 - 0.36 9.7 4.0 0.43 9.4 4.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF3043 PF11241.8 EKX53908.1 - 0.38 10.8 8.5 0.61 10.1 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) SpoIIP PF07454.11 EKX53908.1 - 0.39 10.1 14.9 0.59 9.5 14.9 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) SprA-related PF12118.8 EKX53908.1 - 0.46 9.6 22.6 0.64 9.1 22.6 1.1 1 0 0 1 1 1 0 SprA-related family Rxt3 PF08642.10 EKX53908.1 - 0.48 11.2 5.7 0.81 10.5 5.7 1.3 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 TFIIA PF03153.13 EKX53908.1 - 0.5 10.3 26.7 0.7 9.8 26.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CPSF100_C PF13299.6 EKX53908.1 - 0.52 10.5 11.9 0.81 9.8 11.9 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF853 PF05872.12 EKX53908.1 - 0.58 8.7 7.9 0.76 8.3 7.9 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) RPN2_C PF18004.1 EKX53908.1 - 0.62 10.0 18.1 1 9.2 15.8 2.0 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4228 PF14009.6 EKX53908.1 - 0.63 10.4 6.7 1 9.7 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) CDC45 PF02724.14 EKX53908.1 - 0.69 8.1 11.8 0.96 7.7 11.8 1.1 1 0 0 1 1 1 0 CDC45-like protein CSG2 PF16965.5 EKX53908.1 - 0.69 8.8 5.4 0.99 8.3 5.4 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator DUF2722 PF10846.8 EKX53908.1 - 0.72 8.7 26.9 1.1 8.2 26.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Peptidase_S49_N PF08496.10 EKX53908.1 - 0.75 9.9 14.1 1.2 9.2 14.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Band_3_cyto PF07565.13 EKX53908.1 - 0.82 9.4 12.2 1.3 8.7 12.2 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Spt20 PF12090.8 EKX53908.1 - 0.9 9.1 36.4 1.6 8.2 36.4 1.3 1 0 0 1 1 1 0 Spt20 family G0-G1_switch_2 PF15103.6 EKX53908.1 - 0.93 10.0 9.9 2.2 8.8 9.9 1.6 1 0 0 1 1 1 0 G0/G1 switch protein 2 Ureide_permease PF07168.11 EKX53908.1 - 1 8.1 5.8 1.3 7.6 5.8 1.1 1 0 0 1 1 1 0 Ureide permease CLN3 PF02487.17 EKX53908.1 - 1.2 8.2 8.9 1.7 7.6 8.9 1.2 1 0 0 1 1 1 0 CLN3 protein Pex26 PF07163.12 EKX53908.1 - 1.3 8.3 11.9 2.3 7.4 11.9 1.4 1 0 0 1 1 1 0 Pex26 protein Gti1_Pac2 PF09729.9 EKX53908.1 - 1.4 9.0 11.5 2.2 8.3 11.5 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family V_ATPase_I PF01496.19 EKX53908.1 - 1.4 6.7 12.6 1.8 6.4 12.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Bud13 PF09736.9 EKX53908.1 - 1.6 9.1 22.2 3.5 8.0 22.2 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF3381 PF11861.8 EKX53908.1 - 1.6 8.5 22.2 2.7 7.8 22.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF5349 PF17298.2 EKX53908.1 - 1.8 8.3 11.8 2.8 7.6 11.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Peroxin-13_N PF04088.13 EKX53908.1 - 2.1 8.6 7.4 3.6 7.9 7.4 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region EPL1 PF10513.9 EKX53908.1 - 2.2 8.7 15.1 3.8 7.9 15.1 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Peptidase_U57 PF05582.12 EKX53908.1 - 2.2 7.4 8.8 3.4 6.9 8.8 1.2 1 0 0 1 1 1 0 YabG peptidase U57 DUF4770 PF15994.5 EKX53908.1 - 2.7 8.2 15.3 4.8 7.4 15.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) ALMT PF11744.8 EKX53908.1 - 3 6.6 9.4 4.7 5.9 9.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Hid1 PF12722.7 EKX53908.1 - 3.3 5.7 12.0 4.5 5.3 12.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ctr PF04145.15 EKX53908.1 - 3.7 8.2 6.8 6.5 7.4 6.8 1.4 1 0 0 1 1 1 0 Ctr copper transporter family Coilin_N PF15862.5 EKX53908.1 - 3.7 7.3 21.1 6.5 6.6 21.1 1.3 1 0 0 1 1 1 0 Coilin N-terminus PPL5 PF18168.1 EKX53908.1 - 3.8 6.7 11.7 5.4 6.2 11.7 1.1 1 0 0 1 1 1 0 Prim-pol family 5 DUF3464 PF11947.8 EKX53908.1 - 4 7.2 15.7 6.2 6.6 15.7 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF2126 PF09899.9 EKX53908.1 - 4.1 5.4 11.9 0.04 12.0 4.0 1.5 2 0 0 2 2 2 0 Putative amidoligase enzyme (DUF2126) Folate_carrier PF01770.18 EKX53908.1 - 4.7 5.8 8.0 6.9 5.3 8.0 1.2 1 0 0 1 1 1 0 Reduced folate carrier CobT PF06213.12 EKX53908.1 - 5 6.4 21.4 7.3 5.9 21.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FHIPEP PF00771.20 EKX53908.1 - 5.2 5.4 8.0 7.1 5.0 8.0 1.1 1 0 0 1 1 1 0 FHIPEP family Borrelia_P83 PF05262.11 EKX53908.1 - 5.5 5.4 17.6 7.2 5.0 17.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Med15 PF09606.10 EKX53908.1 - 7.5 5.1 25.5 10 4.7 25.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Sec62 PF03839.16 EKX53908.1 - 7.7 6.0 14.3 13 5.2 14.3 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DUF702 PF05142.12 EKX53908.1 - 7.9 6.9 17.7 8.2 6.9 14.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF702) O-antigen_lig PF13425.6 EKX53908.1 - 8.9 5.0 7.7 13 4.5 7.7 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein FAM176 PF14851.6 EKX53908.1 - 9.6 5.9 9.7 20 4.8 9.7 1.5 1 0 0 1 1 1 0 FAM176 family SQHop_cyclase_C PF13243.6 EKX53909.1 - 1.3e-45 155.9 3.0 4.4e-45 154.2 3.0 1.7 1 1 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 EKX53909.1 - 5.9e-28 96.3 7.8 1.3e-13 50.4 0.5 5.3 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 EKX53909.1 - 4.5e-07 29.5 0.7 0.098 12.0 0.0 3.5 4 0 0 4 4 4 3 Pectic acid lyase SQHop_cyclase_N PF13249.6 EKX53909.1 - 1.7e-06 27.3 0.2 0.089 11.9 0.0 3.8 3 1 1 4 4 4 3 Squalene-hopene cyclase N-terminal domain TED_complement PF07678.14 EKX53909.1 - 0.0045 16.1 0.2 0.03 13.4 0.0 2.3 2 1 0 2 2 2 1 A-macroglobulin TED domain Mago-bind PF09282.10 EKX53909.1 - 0.029 14.2 1.2 0.15 12.0 0.3 2.2 2 0 0 2 2 2 0 Mago binding GST_N PF02798.20 EKX53910.1 - 6.4e-15 55.3 0.0 1.2e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EKX53910.1 - 7.1e-11 42.2 0.2 1.4e-10 41.3 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EKX53910.1 - 2.1e-08 34.4 0.0 4.3e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EKX53910.1 - 0.00012 22.3 0.0 0.00025 21.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EKX53910.1 - 0.00017 21.8 0.1 0.00037 20.6 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EKX53910.1 - 0.036 14.8 0.0 0.17 12.6 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 EKX53910.1 - 0.072 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Pkinase PF00069.25 EKX53911.1 - 4.4e-68 229.5 0.0 5.6e-68 229.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX53911.1 - 7.5e-30 104.1 0.0 9.6e-30 103.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX53911.1 - 0.00019 20.9 0.0 0.0003 20.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EKX53911.1 - 0.0036 16.7 0.0 0.0057 16.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EKX53911.1 - 0.0055 15.5 0.0 0.0083 14.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Arm PF00514.23 EKX53912.1 - 0.0004 20.3 0.0 0.08 13.0 0.0 3.7 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EKX53912.1 - 0.0023 18.3 4.3 0.78 10.2 0.1 4.5 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 EKX53912.1 - 0.014 15.6 0.1 0.89 10.0 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat V-ATPase_H_C PF11698.8 EKX53912.1 - 0.06 13.5 1.6 2.5 8.2 0.0 3.7 3 1 1 4 4 4 0 V-ATPase subunit H Cnd1 PF12717.7 EKX53912.1 - 0.064 13.3 1.1 4.6 7.3 0.0 3.5 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EKX53912.1 - 0.089 13.3 0.9 8.8 6.9 0.0 3.9 3 0 0 3 3 3 0 HEAT-like repeat MIP PF00230.20 EKX53913.1 - 1.3e-34 119.9 9.7 1.5e-34 119.7 9.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein Transgly_assoc PF04226.13 EKX53913.1 - 0.074 13.3 2.6 0.23 11.7 2.6 1.8 1 0 0 1 1 1 0 Transglycosylase associated protein UBA PF00627.31 EKX53914.1 - 9.7e-10 38.2 0.5 1.5e-09 37.5 0.5 1.3 1 0 0 1 1 1 1 UBA/TS-N domain HTH_8 PF02954.19 EKX53914.1 - 0.088 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family CUE PF02845.16 EKX53914.1 - 0.097 12.4 0.2 0.33 10.7 0.2 1.9 1 1 0 1 1 1 0 CUE domain DUF2291 PF10054.9 EKX53914.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2291) SHIPPO-rpt PF07004.12 EKX53917.1 - 0.022 15.6 4.3 0.38 11.8 0.0 2.6 2 0 0 2 2 2 0 Sperm-tail PG-rich repeat FerA PF08165.11 EKX53919.1 - 0.0071 16.3 2.1 0.06 13.3 0.3 2.5 2 0 0 2 2 2 1 FerA (NUC095) domain RETICULATA-like PF11891.8 EKX53920.1 - 8.8e-22 77.8 0.4 2.3e-20 73.2 0.4 2.3 1 1 0 1 1 1 1 Protein RETICULATA-related DUF179 PF02622.15 EKX53921.1 - 4.8e-27 94.9 0.0 6.9e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 Ank_2 PF12796.7 EKX53922.1 - 3.8e-19 69.0 0.0 3.7e-08 33.8 0.0 3.9 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank PF00023.30 EKX53922.1 - 5.4e-13 48.8 0.4 0.00011 22.4 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EKX53922.1 - 3.3e-10 40.0 0.0 1.3e-06 28.6 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX53922.1 - 6.7e-09 36.1 0.4 1.7e-05 25.3 0.0 3.6 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX53922.1 - 2.6e-08 33.5 0.0 0.54 11.0 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Importin_rep_4 PF18808.1 EKX53923.1 - 4e-16 59.1 6.3 1.6e-15 57.1 0.2 3.5 3 0 0 3 3 2 1 Importin repeat HEAT_2 PF13646.6 EKX53923.1 - 5.2e-11 42.8 3.9 0.002 18.5 0.0 7.5 6 2 2 8 8 8 2 HEAT repeats HEAT PF02985.22 EKX53923.1 - 7.6e-09 35.1 10.9 0.24 11.8 0.0 9.2 12 0 0 12 12 11 3 HEAT repeat Importin_rep_6 PF18829.1 EKX53923.1 - 9.8e-08 32.1 7.9 1.4e-07 31.6 0.5 4.2 5 0 0 5 5 5 1 Importin repeat 6 ParcG PF10274.9 EKX53923.1 - 3.8e-06 27.2 0.4 2.7e-05 24.4 0.1 2.6 3 0 0 3 3 3 1 Parkin co-regulated protein RIX1 PF08167.12 EKX53923.1 - 1.3e-05 25.0 5.2 0.22 11.2 0.1 4.8 4 2 0 4 4 4 2 rRNA processing/ribosome biogenesis DUF3385 PF11865.8 EKX53923.1 - 1.5e-05 24.9 1.9 2.3 8.1 0.1 5.9 4 3 3 7 7 7 2 Domain of unknown function (DUF3385) MMS19_C PF12460.8 EKX53923.1 - 2.3e-05 23.7 2.1 0.86 8.7 0.0 4.8 5 0 0 5 5 5 2 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.6 EKX53923.1 - 0.00021 21.7 10.8 3.2 8.4 0.0 9.1 10 1 2 12 12 11 1 HEAT-like repeat DRIM PF07539.12 EKX53923.1 - 0.0019 16.6 2.5 0.044 12.1 0.1 3.5 3 1 0 4 4 4 1 Down-regulated in metastasis IBN_N PF03810.19 EKX53923.1 - 0.0024 17.8 2.9 0.006 16.5 0.0 3.2 4 0 0 4 4 3 1 Importin-beta N-terminal domain CLASP_N PF12348.8 EKX53923.1 - 0.013 15.1 3.0 7 6.1 0.1 4.8 6 1 0 6 6 6 0 CLASP N terminal GCIP PF13324.6 EKX53923.1 - 0.027 14.1 1.5 0.085 12.4 1.5 1.8 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Tti2 PF10521.9 EKX53923.1 - 0.027 14.0 1.9 12 5.4 0.0 5.0 4 2 2 6 6 6 0 Tti2 family HIGH_NTase1 PF05636.11 EKX53923.1 - 0.031 13.5 2.0 0.059 12.6 2.0 1.4 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase Mito_carr PF00153.27 EKX53925.1 - 2.5e-07 30.5 0.0 3.2e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein Histone_H2A_C PF16211.5 EKX53926.1 - 6.3e-19 67.4 1.3 1.7e-18 66.0 1.3 1.8 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EKX53926.1 - 4.8e-18 65.8 0.3 7.2e-18 65.2 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EKX53926.1 - 0.00061 20.0 0.0 0.00092 19.4 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Chloroa_b-bind PF00504.21 EKX53927.1 - 4.3e-30 105.4 0.1 5.3e-30 105.1 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Chloroa_b-bind PF00504.21 EKX53928.1 - 3e-37 128.6 0.5 1.5e-25 90.6 0.2 1.6 1 1 1 2 2 2 2 Chlorophyll A-B binding protein PHM7_cyt PF14703.6 EKX53929.1 - 5.8e-08 33.2 0.4 0.001 19.3 0.0 2.8 1 1 1 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RRM_1 PF00076.22 EKX53929.1 - 8.9e-07 28.6 0.0 3.7e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Anoctamin PF04547.12 EKX53929.1 - 0.086 11.7 8.0 1.1 8.0 2.5 2.8 2 1 0 2 2 2 0 Calcium-activated chloride channel RL PF17797.1 EKX53929.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 RL domain Cas_GSU0053 PF09617.10 EKX53930.1 - 0.027 14.4 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) DOT1 PF08123.13 EKX53930.1 - 0.034 13.7 0.1 0.085 12.4 0.0 1.7 2 0 0 2 2 2 0 Histone methylation protein DOT1 TPR_2 PF07719.17 EKX53932.1 - 0.00037 20.4 3.2 2.2 8.6 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX53932.1 - 0.00059 19.8 0.3 2.5 8.5 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX53932.1 - 0.0008 19.9 3.3 9.5 7.1 0.0 5.5 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX53932.1 - 0.0026 17.5 0.7 0.97 9.4 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat LEDGF PF11467.8 EKX53932.1 - 0.0041 16.7 1.9 0.0077 15.8 0.5 2.1 2 0 0 2 2 2 1 Lens epithelium-derived growth factor (LEDGF) TPR_14 PF13428.6 EKX53932.1 - 0.0083 16.9 4.6 0.08 13.8 0.1 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX53932.1 - 0.07 13.6 8.9 0.21 12.1 0.3 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat DFRP_C PF16543.5 EKX53932.1 - 0.17 12.4 2.6 0.4 11.2 2.6 1.6 1 0 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 zn-ribbon_14 PF16503.5 EKX53932.1 - 0.19 11.3 2.8 8.8 5.9 0.1 3.1 3 0 0 3 3 3 0 Zinc-ribbon BTAD PF03704.17 EKX53932.1 - 1.4 9.3 5.9 18 5.8 0.4 3.1 3 1 0 3 3 3 0 Bacterial transcriptional activator domain ATG22 PF11700.8 EKX53933.1 - 5.7e-62 209.9 15.1 6.6e-62 209.7 15.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like NPV_P10 PF05531.12 EKX53934.1 - 0.013 15.9 0.7 0.038 14.5 0.6 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.6 EKX53934.1 - 0.015 14.0 8.6 0.017 13.8 8.6 1.1 1 0 0 1 1 1 0 AAA domain TMF_TATA_bd PF12325.8 EKX53934.1 - 0.058 13.6 19.1 0.062 13.5 15.8 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.19 EKX53934.1 - 0.98 7.3 7.1 1.1 7.1 7.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_20 PF14561.6 EKX53934.1 - 3.2 8.1 8.0 17 5.9 2.7 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Pox_A_type_inc PF04508.12 EKX53934.1 - 5.6 7.0 9.8 0.4 10.6 0.9 3.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Imm26 PF15428.6 EKX53935.1 - 0.11 12.8 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 26 Ion_trans PF00520.31 EKX53936.1 - 3.8e-12 46.0 10.0 5.6e-12 45.4 10.0 1.1 1 0 0 1 1 1 1 Ion transport protein PH PF00169.29 EKX53936.1 - 0.0011 19.5 0.0 0.0017 18.8 0.0 1.4 1 0 0 1 1 1 1 PH domain Ion_trans PF00520.31 EKX53939.1 - 2.5e-130 433.0 87.7 3.1e-44 151.1 13.4 4.2 4 0 0 4 4 4 4 Ion transport protein Dockerin_1 PF00404.18 EKX53939.1 - 0.0014 18.8 0.1 0.0034 17.5 0.1 1.6 1 0 0 1 1 1 1 Dockerin type I domain Replic_Relax PF13814.6 EKX53939.1 - 0.028 14.5 0.1 4.4 7.3 0.0 2.6 2 0 0 2 2 2 0 Replication-relaxation DUF4320 PF14208.6 EKX53939.1 - 0.11 12.5 0.3 0.42 10.7 0.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) cobW PF02492.19 EKX53940.1 - 6.2e-48 162.7 0.1 8.3e-48 162.3 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EKX53940.1 - 1.7e-22 79.2 0.1 2.9e-22 78.4 0.1 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MeaB PF03308.16 EKX53940.1 - 0.0026 16.8 0.1 0.47 9.4 0.0 2.6 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 EKX53940.1 - 0.0033 17.3 0.3 3 7.7 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EKX53940.1 - 0.0055 17.1 1.7 0.043 14.2 1.7 2.3 1 1 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 EKX53940.1 - 0.011 15.7 0.2 0.028 14.4 0.2 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE GTP_EFTU PF00009.27 EKX53940.1 - 0.022 14.3 0.0 4.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EKX53940.1 - 0.052 13.8 0.5 1.5 9.1 0.1 2.6 2 1 0 2 2 2 0 AAA domain MobB PF03205.14 EKX53940.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 EKX53940.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 EKX53940.1 - 0.13 12.4 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EKX53940.1 - 0.19 11.5 0.1 0.65 9.8 0.1 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain SDA1 PF05285.12 EKX53941.1 - 1.8 7.9 12.2 2.1 7.7 12.2 1.2 1 0 0 1 1 1 0 SDA1 Pkinase PF00069.25 EKX53942.1 - 2.6e-72 243.4 0.0 3.4e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX53942.1 - 3.4e-34 118.3 0.0 5.2e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 EKX53942.1 - 1.1e-07 32.4 0.1 2.7e-07 31.0 0.1 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 EKX53942.1 - 5.7e-05 22.6 0.0 0.00034 20.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EKX53942.1 - 0.00093 18.1 0.2 0.043 12.6 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase DUF3644 PF12358.8 EKX53942.1 - 0.19 12.2 0.8 20 5.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3644) Thioredoxin PF00085.20 EKX53943.1 - 4.3e-06 26.7 0.0 9.1e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Corona_S2 PF01601.16 EKX53943.1 - 0.19 10.2 0.1 0.22 10.0 0.1 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Zip PF02535.22 EKX53946.1 - 0.029 13.6 19.2 0.098 11.9 0.1 3.5 2 1 0 3 3 3 0 ZIP Zinc transporter Ank_2 PF12796.7 EKX53949.1 - 1.5e-10 41.5 0.0 4e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EKX53949.1 - 1.8e-09 37.6 0.0 8e-05 22.9 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EKX53949.1 - 6.2e-09 36.2 0.2 0.00017 22.0 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX53949.1 - 5.5e-08 32.5 0.0 0.0003 21.0 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EKX53949.1 - 1.5e-06 28.4 0.0 0.00011 22.4 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) MecA PF05389.12 EKX53949.1 - 6 6.4 30.9 60 3.2 10.2 3.3 1 1 1 2 2 2 0 Negative regulator of genetic competence (MecA) Nitroreductase PF00881.24 EKX53949.1 - 7 6.7 6.5 9 6.3 4.1 2.1 1 1 1 2 2 2 0 Nitroreductase family Ribosomal_S17 PF00366.20 EKX53950.1 - 0.00069 19.7 32.9 1.2 9.3 1.2 7.1 1 1 2 3 3 3 1 Ribosomal protein S17 DUF960 PF06124.11 EKX53950.1 - 0.0038 17.8 13.9 33 5.2 0.2 6.5 1 1 6 7 7 7 0 Staphylococcal protein of unknown function (DUF960) CbiG_N PF11760.8 EKX53950.1 - 0.0077 16.2 17.6 15 5.7 0.1 7.0 2 2 5 8 8 8 1 Cobalamin synthesis G N-terminal Fer4_15 PF13459.6 EKX53950.1 - 0.22 12.3 21.1 4.8 8.0 0.7 5.5 1 1 2 3 3 3 0 4Fe-4S single cluster domain DUF3332 PF11810.8 EKX53950.1 - 3.3 7.3 18.1 1.3e+04 -4.4 18.2 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3332) DUF3910 PF13049.6 EKX53950.1 - 3.7 7.9 19.3 24 5.3 1.2 5.8 1 1 4 5 5 5 0 Protein of unknown function (DUF3910) AAA_34 PF13872.6 EKX53952.1 - 2.3e-116 387.9 0.0 3.7e-116 387.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 EKX53952.1 - 2e-100 335.9 0.5 3.4e-100 335.2 0.5 1.4 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue ABC1 PF03109.16 EKX53953.1 - 7.2e-23 81.0 0.0 1.2e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EKX53953.1 - 0.0024 17.8 0.6 0.22 11.4 0.2 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 EKX53953.1 - 0.011 15.1 0.4 0.023 14.1 0.1 1.6 2 0 0 2 2 2 0 Protein kinase domain HALZ PF02183.18 EKX53954.1 - 0.048 13.9 1.7 2.8 8.2 0.1 3.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper EutQ PF06249.12 EKX53954.1 - 1.3 8.7 4.1 0.44 10.3 0.3 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutQ DUF3837 PF12939.7 EKX53954.1 - 1.4 9.3 8.7 34 4.9 0.0 4.0 4 1 0 4 4 4 0 Domain of unknown function (DUF3837) Sugarporin_N PF11471.8 EKX53954.1 - 1.9 8.5 13.7 0.87 9.6 4.0 3.3 3 1 1 4 4 4 0 Maltoporin periplasmic N-terminal extension Vir_act_alpha_C PF10400.9 EKX53954.1 - 2.3 9.0 5.1 29 5.4 0.6 3.1 2 1 1 3 3 3 0 Virulence activator alpha C-term DUF4407 PF14362.6 EKX53954.1 - 2.9 7.2 11.4 6.9 5.9 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TMPIT PF07851.13 EKX53954.1 - 6.3 5.9 8.0 11 5.2 0.1 2.3 2 0 0 2 2 2 0 TMPIT-like protein Aminotran_1_2 PF00155.21 EKX53956.1 - 9.3e-43 146.8 0.0 1.3e-42 146.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EKX53956.1 - 0.00032 19.8 0.0 0.0013 17.7 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V SHIPPO-rpt PF07004.12 EKX53960.1 - 3.2e-16 59.4 30.2 0.46 11.5 0.0 10.4 10 0 0 10 10 10 8 Sperm-tail PG-rich repeat His_Phos_1 PF00300.22 EKX53960.1 - 2.2e-13 50.3 0.2 6.4e-13 48.8 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) HSBP1 PF06825.12 EKX53961.1 - 0.0025 17.7 1.3 0.007 16.2 1.3 1.8 1 0 0 1 1 1 1 Heat shock factor binding protein 1 CLZ PF16526.5 EKX53961.1 - 0.11 12.9 0.1 0.25 11.7 0.1 1.6 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HSBP1 PF06825.12 EKX53963.1 - 0.092 12.6 0.2 0.25 11.2 0.2 1.7 1 0 0 1 1 1 0 Heat shock factor binding protein 1 HSBP1 PF06825.12 EKX53965.1 - 0.0037 17.1 1.7 0.0096 15.8 1.7 1.7 1 0 0 1 1 1 1 Heat shock factor binding protein 1 CLZ PF16526.5 EKX53965.1 - 0.076 13.4 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PMSR PF01625.21 EKX53966.1 - 5e-54 182.6 0.8 6.7e-54 182.2 0.8 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase RAMA PF18755.1 EKX53967.1 - 3.4e-14 53.2 0.1 7.9e-14 52.0 0.1 1.6 1 0 0 1 1 1 1 Restriction Enzyme Adenine Methylase Associated ARID PF01388.21 EKX53967.1 - 1.6e-10 41.5 0.0 4.1e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF3350 PF11830.8 EKX53968.1 - 0.24 11.7 0.0 1.1 9.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3350) CobS PF02654.15 EKX53970.1 - 5.1e-40 137.9 16.0 6.4e-40 137.5 16.0 1.1 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase zf-B_box PF00643.24 EKX53971.1 - 2.5e-10 40.3 18.8 9.8e-10 38.4 2.8 3.6 5 0 0 5 5 5 2 B-box zinc finger zf-RING_UBOX PF13445.6 EKX53971.1 - 4.9e-07 29.7 3.4 4.9e-07 29.7 3.4 3.8 3 2 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EKX53971.1 - 1.6e-06 28.2 6.7 1.6e-06 28.2 6.7 4.1 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING fn3 PF00041.21 EKX53971.1 - 2.7e-05 24.4 0.0 5.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain zf-C3HC4_3 PF13920.6 EKX53971.1 - 3.4e-05 23.6 7.3 3.4e-05 23.6 7.3 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Pur_ac_phosph_N PF16656.5 EKX53971.1 - 5.4e-05 23.7 0.0 0.00011 22.8 0.0 1.4 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain DUF1664 PF07889.12 EKX53971.1 - 0.0033 17.5 0.6 0.0033 17.5 0.6 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) CENP-Q PF13094.6 EKX53971.1 - 0.023 14.9 3.1 0.04 14.1 3.1 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TMF_TATA_bd PF12325.8 EKX53971.1 - 0.56 10.4 9.3 9.7 6.5 3.4 3.3 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding CEBP_ZZ PF16366.5 EKX53971.1 - 2.7 8.3 20.0 0.31 11.3 8.1 2.8 1 1 1 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain FYDLN_acid PF09538.10 EKX53975.1 - 0.013 16.1 1.8 0.013 16.1 1.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) Hid1 PF12722.7 EKX53975.1 - 1.3 7.0 3.2 1.5 6.9 3.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF5486 PF17588.2 EKX53976.1 - 0.091 12.7 1.1 0.36 10.7 0.0 2.3 1 1 0 2 2 2 0 Family of unknown function (DUF5486) Filamin PF00630.19 EKX53977.1 - 3.7e-18 66.2 0.2 1.8e-06 28.7 0.0 6.2 5 1 0 5 5 5 3 Filamin/ABP280 repeat Invasin_D3 PF09134.10 EKX53977.1 - 2.6e-11 43.7 0.3 0.019 15.3 0.0 5.2 5 1 0 5 5 5 3 Invasin, domain 3 PDZ_6 PF17820.1 EKX53977.1 - 1.4e-06 28.1 2.1 0.0067 16.3 0.6 2.9 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 EKX53977.1 - 6.2e-05 23.3 3.1 0.097 13.0 0.4 3.4 4 0 0 4 4 4 2 PDZ domain PDZ_2 PF13180.6 EKX53977.1 - 0.0029 17.9 2.7 2 8.8 0.0 3.2 4 0 0 4 4 4 2 PDZ domain Tricorn_PDZ PF14685.6 EKX53977.1 - 0.011 15.7 0.1 0.12 12.4 0.1 2.5 2 0 0 2 2 2 0 Tricorn protease PDZ domain Sec23_trunk PF04811.15 EKX53978.1 - 0.001 18.7 3.4 0.0033 17.0 3.4 1.7 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain DUF3435 PF11917.8 EKX53978.1 - 0.4 9.6 11.0 0.46 9.4 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) RNA_pol_L PF01193.24 EKX53978.1 - 0.41 10.1 2.1 0.43 10.1 0.1 2.1 2 1 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain ALMT PF11744.8 EKX53978.1 - 0.7 8.7 12.0 0.88 8.3 12.0 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter PI3K_1B_p101 PF10486.9 EKX53978.1 - 0.73 7.5 13.9 0.9 7.2 13.9 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Vps16_N PF04841.13 EKX53978.1 - 0.83 8.3 9.2 1.1 7.9 9.2 1.2 1 0 0 1 1 1 0 Vps16, N-terminal region YjbH PF06082.11 EKX53978.1 - 2.8 6.6 10.0 3.4 6.4 10.0 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH IHABP4_N PF16174.5 EKX53978.1 - 3.6 8.2 18.1 5.9 7.5 18.1 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF4407 PF14362.6 EKX53978.1 - 4 6.7 15.3 6.5 6.0 15.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Neur_chan_memb PF02932.16 EKX53978.1 - 4.8 7.2 6.6 6.1 6.8 6.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PA26 PF04636.13 EKX53978.1 - 5.6 5.8 14.7 27 3.5 14.7 1.8 1 1 0 1 1 1 0 PA26 p53-induced protein (sestrin) BshC PF10079.9 EKX53978.1 - 7.8 5.1 15.3 9.7 4.8 15.3 1.2 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC LMBR1 PF04791.16 EKX53978.1 - 9.4 5.0 13.3 13 4.6 13.3 1.2 1 1 0 1 1 1 0 LMBR1-like membrane protein BPTA PF17044.5 EKX53979.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Borrelial persistence in ticks protein A Con-6 PF10346.9 EKX53979.1 - 0.53 10.4 8.2 1.5 8.9 0.4 3.6 3 0 0 3 3 3 0 Conidiation protein 6 PPR_2 PF13041.6 EKX53980.1 - 3.5e-13 49.5 0.4 3.1e-07 30.5 0.0 3.1 1 1 2 3 3 3 3 PPR repeat family PPR_long PF17177.4 EKX53980.1 - 6e-11 42.1 0.2 6.1e-10 38.8 0.1 2.2 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP EF-hand_7 PF13499.6 EKX53980.1 - 9.4e-11 42.0 1.9 3.1e-07 30.7 0.2 2.9 2 0 0 2 2 2 2 EF-hand domain pair PPR_3 PF13812.6 EKX53980.1 - 1.1e-09 38.2 0.1 6.6e-05 22.9 0.2 3.3 2 1 1 3 3 3 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 EKX53980.1 - 2e-09 37.0 0.6 1.2e-05 24.8 0.1 3.6 3 0 0 3 3 3 1 PPR repeat EF-hand_6 PF13405.6 EKX53980.1 - 1e-08 34.4 5.3 0.00081 19.1 0.2 4.3 3 1 1 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 EKX53980.1 - 5.8e-08 31.7 12.7 0.00025 20.3 0.0 4.1 5 0 0 5 5 5 2 EF hand PPR PF01535.20 EKX53980.1 - 1.3e-05 25.1 6.4 0.0078 16.4 0.1 3.8 4 0 0 4 4 4 2 PPR repeat EF-hand_4 PF12763.7 EKX53980.1 - 0.0013 18.7 2.1 1.4 8.9 0.4 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 EKX53980.1 - 0.0016 17.9 12.4 0.036 13.6 0.2 4.4 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 EKX53980.1 - 0.0036 17.1 3.4 1.1 9.2 1.4 3.1 2 0 0 2 2 2 2 EF-hand domain pair DUF2390 PF09523.10 EKX53980.1 - 0.039 14.3 0.8 0.11 12.8 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) TetR_C_9 PF14514.6 EKX53980.1 - 0.083 13.0 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain RFC1 PF08519.12 EKX53981.1 - 3.6e-40 137.7 0.0 1.3e-39 135.9 0.0 2.0 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 EKX53981.1 - 4.7e-15 55.7 0.0 1.8e-14 53.9 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 EKX53981.1 - 3.5e-14 53.4 0.0 9.3e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EKX53981.1 - 4.7e-07 30.1 0.0 1.3e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EKX53981.1 - 6.9e-05 22.9 0.0 0.00021 21.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EKX53981.1 - 0.00024 21.5 0.0 0.00079 19.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 EKX53981.1 - 0.00095 19.1 0.0 0.0034 17.3 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain PTCB-BRCT PF12738.7 EKX53981.1 - 0.0018 18.1 0.0 0.0054 16.7 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain AAA_30 PF13604.6 EKX53981.1 - 0.0029 17.4 0.0 0.012 15.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EKX53981.1 - 0.0066 16.8 0.0 0.027 14.9 0.0 2.1 1 1 0 1 1 1 1 RNA helicase AAA_19 PF13245.6 EKX53981.1 - 0.0073 16.6 0.3 0.091 13.1 0.2 2.7 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EKX53981.1 - 0.015 15.1 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 EKX53981.1 - 0.025 14.5 0.0 0.066 13.1 0.0 1.8 1 0 0 1 1 1 0 NTPase AAA_assoc_2 PF16193.5 EKX53981.1 - 0.05 13.9 0.0 0.25 11.7 0.0 2.2 1 0 0 1 1 1 0 AAA C-terminal domain AAA_7 PF12775.7 EKX53981.1 - 0.064 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region BRCT_2 PF16589.5 EKX53981.1 - 0.066 13.6 0.0 5.6 7.4 0.0 3.0 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain AAA_11 PF13086.6 EKX53981.1 - 0.1 12.3 0.0 0.1 12.3 0.0 5.0 3 1 0 4 4 3 0 AAA domain AAA_5 PF07728.14 EKX53981.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) EMP24_GP25L PF01105.24 EKX53982.1 - 0.22 11.4 4.8 0.3 11.0 4.7 1.3 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD ABATE PF07336.11 EKX53982.1 - 0.45 11.2 4.9 0.19 12.4 1.2 2.0 2 0 0 2 2 2 0 Putative stress-induced transcription regulator DUF5101 PF17031.5 EKX53983.1 - 0.0058 16.7 0.0 0.76 9.9 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF5101) WD40 PF00400.32 EKX53984.1 - 0.00052 20.8 2.7 0.56 11.2 0.1 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX53984.1 - 0.00063 20.0 0.0 0.44 10.9 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF2390 PF09523.10 EKX53985.1 - 0.0015 18.8 0.1 0.0015 18.8 0.1 3.5 3 1 1 4 4 4 1 Protein of unknown function (DUF2390) N_formyltrans_C PF18216.1 EKX53985.1 - 0.048 13.3 0.2 1 9.1 0.0 3.0 3 0 0 3 3 3 0 N-formyltransferase dimerization C-terminal domain PDZ_4 PF17816.1 EKX53985.1 - 0.82 10.1 4.6 4.2 7.8 0.0 2.8 1 1 1 2 2 2 0 PDZ domain NOP5NT PF08156.13 EKX53985.1 - 3.1 8.2 7.4 0.42 11.0 0.8 3.0 3 0 0 3 3 3 0 NOP5NT (NUC127) domain DHC PF09626.10 EKX53985.1 - 6.7 7.6 6.9 2.4 9.1 0.1 3.3 3 1 1 4 4 4 0 Dihaem cytochrome c PetN PF03742.14 EKX53987.1 - 0.029 14.2 0.2 0.074 12.9 0.2 1.7 1 0 0 1 1 1 0 PetN Mcp5_PH PF12814.7 EKX53988.1 - 0.0023 18.0 0.4 0.0023 18.0 0.4 1.9 2 1 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology FapA PF03961.13 EKX53988.1 - 0.091 11.4 2.2 0.12 11.0 2.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 EKX53988.1 - 5.2 7.1 9.4 9.1 6.3 9.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Methyltr_RsmB-F PF01189.17 EKX53989.1 - 1.9e-24 86.4 0.0 2.8e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F DUF2431 PF10354.9 EKX53989.1 - 0.028 14.7 0.0 0.044 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) FtsJ PF01728.19 EKX53989.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Glycos_transf_1 PF00534.20 EKX53990.1 - 4.4e-13 49.1 0.0 1.5e-12 47.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EKX53990.1 - 1.1e-09 38.8 0.0 6.8e-09 36.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EKX53990.1 - 7.1e-07 29.5 0.0 0.00049 20.4 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferases group 1 Pkinase PF00069.25 EKX53991.1 - 2e-52 178.2 0.0 2.7e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX53991.1 - 9.3e-25 87.4 0.1 2e-24 86.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX53991.1 - 0.0031 16.9 0.1 0.0086 15.4 0.1 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EKX53991.1 - 0.021 14.2 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ATG27 PF09451.10 EKX53992.1 - 3.5e-15 56.6 0.0 5.6e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 EKX53992.1 - 2.2e-11 44.0 0.1 8.9e-07 29.1 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.15 EKX53992.1 - 1.2e-05 24.5 0.0 2.4e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Mannose-6-phosphate receptor DUF2650 PF10853.8 EKX53992.1 - 0.17 11.6 0.5 2.1 8.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2650) Ank_5 PF13857.6 EKX53994.1 - 3.5e-09 36.8 0.5 3.4e-05 24.0 0.0 4.5 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX53994.1 - 7.5e-08 32.1 2.5 0.0058 17.0 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat Ank_2 PF12796.7 EKX53994.1 - 4.9e-06 27.0 0.3 0.0028 18.2 0.1 3.9 3 1 2 5 5 5 2 Ankyrin repeats (3 copies) CHAT PF12770.7 EKX53994.1 - 0.00012 21.5 0.1 0.00024 20.6 0.1 1.4 1 0 0 1 1 1 1 CHAT domain Ank PF00023.30 EKX53994.1 - 0.00024 21.4 0.4 0.013 15.9 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeat DUF4258 PF14076.6 EKX53994.1 - 0.00033 21.0 0.0 0.001 19.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4258) Ank_4 PF13637.6 EKX53994.1 - 0.0024 18.4 0.7 0.026 15.1 0.0 3.1 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX53995.1 - 4.1e-09 36.5 2.8 0.00024 21.3 0.1 4.8 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX53995.1 - 1.2e-08 34.5 4.9 0.0022 18.4 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 EKX53995.1 - 2.1e-07 31.4 0.2 0.00011 22.7 0.1 3.6 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX53995.1 - 0.00011 22.4 3.8 0.0023 18.3 0.0 3.9 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 EKX53995.1 - 0.0087 16.6 2.2 0.24 12.0 0.0 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) UL45 PF05473.12 EKX53995.1 - 0.11 12.1 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like U-box PF04564.15 EKX53997.1 - 1.9e-10 40.7 0.0 5.7e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 U-box domain HATPase_c_3 PF13589.6 EKX53997.1 - 6.7e-06 26.0 0.0 0.012 15.4 0.0 2.8 2 1 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-Nse PF11789.8 EKX53997.1 - 0.00066 19.4 0.0 0.002 17.9 0.0 1.9 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit CARD_2 PF16739.5 EKX53997.1 - 0.068 13.2 0.0 34 4.5 0.0 3.3 3 0 0 3 3 3 0 Caspase recruitment domain zf-RING_UBOX PF13445.6 EKX53997.1 - 0.11 12.5 0.0 0.39 10.8 0.0 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-NOSIP PF15906.5 EKX53997.1 - 0.12 12.5 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Enkurin PF13864.6 EKX53997.1 - 0.13 12.7 1.7 0.3 11.5 0.0 2.5 2 0 0 2 2 2 0 Calmodulin-binding Gar1 PF04410.14 EKX53998.1 - 6.7e-35 120.1 0.0 8.1e-35 119.9 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region TRAP-delta PF05404.12 EKX53999.1 - 0.14 11.7 0.1 0.5 9.9 0.0 2.0 2 0 0 2 2 2 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) PTCB-BRCT PF12738.7 EKX54001.1 - 9.3e-11 41.5 0.0 1.7e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 EKX54001.1 - 1.5e-08 34.9 0.0 3.8e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EKX54001.1 - 6.1e-06 26.6 0.0 2.8e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Macoilin PF09726.9 EKX54001.1 - 2.3 6.7 10.9 2.8 6.4 10.9 1.2 1 0 0 1 1 1 0 Macoilin family SPATIAL PF15256.6 EKX54001.1 - 2.7 8.3 7.9 4.2 7.7 7.9 1.4 1 0 0 1 1 1 0 SPATIAL Presenilin PF01080.17 EKX54001.1 - 4.7 5.9 12.2 6.3 5.5 12.2 1.3 1 0 0 1 1 1 0 Presenilin Mur_ligase_M PF08245.12 EKX54002.1 - 5.7e-08 33.0 0.2 1e-06 28.9 0.2 2.5 1 1 0 1 1 1 1 Mur ligase middle domain RRM_1 PF00076.22 EKX54003.1 - 5.6e-22 77.3 0.0 8e-22 76.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EKX54003.1 - 4.8e-05 23.4 0.0 7.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 EKX54003.1 - 0.0024 17.8 0.0 0.0045 17.0 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 EKX54003.1 - 0.0044 17.1 0.1 0.0093 16.0 0.1 1.5 1 0 0 1 1 1 1 Limkain b1 PHM7_cyt PF14703.6 EKX54003.1 - 0.0056 16.9 0.1 0.98 9.6 0.1 2.1 1 1 1 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 EKX54003.1 - 0.0095 16.0 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 1 RNA binding motif RRM_occluded PF16842.5 EKX54003.1 - 0.026 14.4 0.0 0.054 13.4 0.0 1.6 1 1 0 1 1 1 0 Occluded RNA-recognition motif Methyltransf_21 PF05050.12 EKX54004.1 - 0.056 13.5 0.0 0.096 12.7 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase FkbM domain PDZ PF00595.24 EKX54010.1 - 1e-09 38.6 0.0 1.9e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX54010.1 - 1.8e-06 27.7 0.0 3.2e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX54010.1 - 7.3e-05 23.0 0.0 0.00014 22.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Pro_isomerase PF00160.21 EKX54010.1 - 0.02 15.2 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ARL2_Bind_BART PF11527.8 EKX54011.1 - 3.5e-24 85.2 1.5 4.8e-24 84.7 1.5 1.2 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART MgtE_N PF03448.17 EKX54013.1 - 1e-15 58.2 19.5 1.2e-05 25.9 0.2 6.7 5 2 0 6 6 6 4 MgtE intracellular N domain HTH_20 PF12840.7 EKX54013.1 - 0.00011 22.2 3.7 0.064 13.3 0.1 3.8 3 0 0 3 3 3 2 Helix-turn-helix domain FliG_M PF14841.6 EKX54013.1 - 0.0071 16.5 2.6 3.1 8.1 0.0 4.6 4 1 0 4 4 4 2 FliG middle domain Hint PF01079.20 EKX54015.1 - 0.012 15.1 0.0 0.019 14.5 0.0 1.3 1 1 0 1 1 1 0 Hint module HIRA_B PF09453.10 EKX54015.1 - 0.38 10.6 1.1 0.76 9.7 1.1 1.5 1 0 0 1 1 1 0 HIRA B motif Arginase PF00491.21 EKX54017.1 - 6.6e-68 229.2 0.0 7.9e-68 229.0 0.0 1.0 1 0 0 1 1 1 1 Arginase family ABC_tran PF00005.27 EKX54018.1 - 3.8e-48 163.5 0.0 1.8e-24 86.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EKX54018.1 - 2.9e-15 56.9 5.3 0.0026 17.6 0.1 4.2 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EKX54018.1 - 3e-09 36.6 0.4 0.18 11.2 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EKX54018.1 - 5.5e-08 33.4 0.2 0.0076 16.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EKX54018.1 - 1.3e-06 28.0 0.0 0.04 13.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EKX54018.1 - 4.3e-06 26.7 0.1 0.01 15.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 EKX54018.1 - 8e-06 25.9 0.5 0.12 12.2 0.1 2.6 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.6 EKX54018.1 - 2.7e-05 24.4 0.4 0.32 11.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 EKX54018.1 - 3.1e-05 24.0 0.0 0.029 14.5 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran_Xtn PF12848.7 EKX54018.1 - 3.9e-05 23.6 6.6 3.9e-05 23.6 6.6 2.4 3 0 0 3 3 2 1 ABC transporter AAA_23 PF13476.6 EKX54018.1 - 5.6e-05 23.7 7.6 0.034 14.7 0.0 3.6 4 0 0 4 4 4 2 AAA domain RNA_helicase PF00910.22 EKX54018.1 - 8.2e-05 22.9 0.0 0.69 10.3 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 EKX54018.1 - 8.6e-05 22.6 0.0 0.54 10.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 EKX54018.1 - 0.00013 21.3 0.1 0.093 11.9 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_22 PF13401.6 EKX54018.1 - 0.00014 22.2 0.1 0.13 12.5 0.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EKX54018.1 - 0.00018 21.3 0.0 0.23 11.1 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 EKX54018.1 - 0.00036 20.5 0.1 0.5 10.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EKX54018.1 - 0.00052 19.7 0.0 0.94 9.0 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 EKX54018.1 - 0.00052 20.3 0.7 0.17 12.1 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EKX54018.1 - 0.00071 20.0 0.1 1.1 9.7 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EKX54018.1 - 0.0023 17.9 0.1 5.9 6.7 0.0 3.1 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 EKX54018.1 - 0.004 17.7 0.2 7.5 7.1 0.0 3.3 4 1 1 5 5 3 0 AAA domain DAP3 PF10236.9 EKX54018.1 - 0.0052 16.0 0.0 1 8.5 0.0 2.3 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 Dynamin_N PF00350.23 EKX54018.1 - 0.006 16.7 0.6 4.5 7.3 0.0 3.0 3 1 0 3 3 3 1 Dynamin family AAA_7 PF12775.7 EKX54018.1 - 0.0075 15.8 0.0 2.8 7.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 EKX54018.1 - 0.01 15.5 0.0 6.9 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF4351 PF14261.6 EKX54018.1 - 0.018 15.1 0.2 0.098 12.7 0.2 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) cobW PF02492.19 EKX54018.1 - 0.021 14.4 0.1 2.6 7.6 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 EKX54018.1 - 0.023 14.6 0.0 11 5.9 0.0 2.9 2 1 1 3 3 3 0 NTPase Rad17 PF03215.15 EKX54018.1 - 0.024 14.5 0.0 3.5 7.5 0.0 2.9 3 0 0 3 3 3 0 Rad17 P-loop domain DUF87 PF01935.17 EKX54018.1 - 0.037 14.1 0.1 0.5 10.4 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 EKX54018.1 - 0.04 13.3 0.1 0.45 9.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Roc PF08477.13 EKX54018.1 - 0.072 13.3 0.0 19 5.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SbcCD_C PF13558.6 EKX54018.1 - 0.15 12.3 0.8 9.6 6.5 0.3 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_27 PF13514.6 EKX54018.1 - 4.8 6.7 8.0 23 4.5 0.0 3.8 4 0 0 4 4 4 0 AAA domain Glyco_transf_6 PF03414.13 EKX54020.1 - 1.1e-27 96.7 0.0 7.1e-16 57.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase family 6 DUF5546 PF17700.1 EKX54020.1 - 0.067 13.6 0.6 4.2 7.8 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5546) RVT_1 PF00078.27 EKX54022.1 - 1.3e-07 31.4 0.0 8e-05 22.3 0.0 2.4 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) ATP11 PF06644.11 EKX54022.1 - 0.022 14.6 2.7 0.038 13.8 2.7 1.3 1 0 0 1 1 1 0 ATP11 protein ORC5_C PF14630.6 EKX54022.1 - 7.3 6.0 10.3 46 3.4 10.3 2.1 1 1 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus PEN-2 PF10251.9 EKX54023.1 - 0.023 15.1 1.9 0.047 14.1 1.9 1.5 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase UPF0561 PF10573.9 EKX54023.1 - 0.93 9.6 3.9 0.4 10.8 1.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 DUF150 PF02576.17 EKX54024.1 - 6.8e-05 23.2 0.0 0.00012 22.4 0.0 1.4 1 0 0 1 1 1 1 RimP N-terminal domain DUF150_C PF17384.2 EKX54024.1 - 0.00013 22.0 0.0 0.00019 21.5 0.0 1.2 1 0 0 1 1 1 1 RimP C-terminal SH3 domain INT_SG_DDX_CT_C PF15300.6 EKX54025.1 - 0.004 16.9 0.1 7.4 6.5 0.0 3.5 3 0 0 3 3 3 1 INTS6/SAGE1/DDX26B/CT45 C-terminus Ribosomal_L5 PF00281.19 EKX54025.1 - 0.15 12.4 7.4 13 6.2 0.0 4.6 4 1 0 4 4 4 0 Ribosomal protein L5 DUF2564 PF10819.8 EKX54025.1 - 0.28 11.6 5.7 5.8 7.4 0.2 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2564) Raf1_N PF18578.1 EKX54025.1 - 4.3 7.9 8.0 7.9 7.0 0.1 4.1 3 2 2 5 5 5 0 Rubisco accumulation factor 1 alpha helical domain PTCB-BRCT PF12738.7 EKX54030.1 - 2e-08 34.0 0.0 5.5e-05 23.0 0.0 4.2 5 0 0 5 5 5 2 twin BRCT domain BRCT PF00533.26 EKX54030.1 - 6.7e-08 32.8 0.0 0.0023 18.2 0.0 3.5 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain DUF4110 PF13422.6 EKX54031.1 - 0.1 12.7 5.9 0.23 11.5 5.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4110) Siah-Interact_N PF09032.11 EKX54032.1 - 0.022 15.1 4.0 0.024 15.0 0.7 2.2 2 0 0 2 2 2 0 Siah interacting protein, N terminal Phage_holin_3_6 PF07332.11 EKX54032.1 - 0.046 13.8 0.0 0.091 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III HemY_N PF07219.13 EKX54032.1 - 0.19 11.9 3.3 1.3 9.3 0.7 2.4 2 0 0 2 2 2 0 HemY protein N-terminus DUF3883 PF13020.6 EKX54033.1 - 3.2e-17 62.3 0.0 7e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) LRR_6 PF13516.6 EKX54034.1 - 8.8e-09 34.7 12.6 0.013 15.5 0.1 5.5 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.7 EKX54034.1 - 0.0003 21.1 5.5 0.29 11.6 0.2 3.2 2 2 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX54034.1 - 0.0098 16.3 1.3 45 5.1 0.0 4.3 5 0 0 5 5 5 0 Leucine Rich Repeat HOASN PF14515.6 EKX54034.1 - 0.12 12.8 0.6 1.6 9.2 0.2 2.5 2 1 0 2 2 2 0 Haem-oxygenase-associated N-terminal helices LRR_8 PF13855.6 EKX54034.1 - 0.56 10.0 7.8 17 5.2 2.7 3.7 2 2 0 2 2 2 0 Leucine rich repeat Baculo_p74_N PF08404.10 EKX54035.1 - 0.018 14.2 0.1 0.027 13.6 0.1 1.2 1 0 0 1 1 1 0 Baculoviridae P74 N-terminal CSTF2_hinge PF14327.6 EKX54035.1 - 0.069 13.6 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 FBPase PF00316.20 EKX54036.1 - 1.9e-59 200.3 0.0 2.5e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Sel1 PF08238.12 EKX54037.1 - 1.5e-16 60.4 19.5 0.00031 21.3 0.4 6.5 6 0 0 6 6 6 5 Sel1 repeat TPR_6 PF13174.6 EKX54037.1 - 7.1e-05 23.2 14.0 0.15 12.8 0.5 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 EKX54037.1 - 0.0068 16.7 2.6 6.9 7.3 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat Dimeth_Pyl PF09505.10 EKX54038.1 - 0.13 10.8 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Dimethylamine methyltransferase (Dimeth_PyL) Tam41_Mmp37 PF09139.11 EKX54038.1 - 0.2 11.0 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial EF-hand_1 PF00036.32 EKX54039.1 - 1.3e-14 52.5 0.1 6.5e-07 28.5 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX54039.1 - 3.9e-12 45.1 0.1 0.00016 21.4 0.0 2.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 EKX54039.1 - 5.9e-11 42.1 0.7 1.6e-09 37.5 0.2 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX54039.1 - 2.8e-10 39.2 0.2 3.8e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX54039.1 - 2.2e-09 37.6 0.0 2.9e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_9 PF14658.6 EKX54039.1 - 2.5e-05 24.5 0.0 3.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.7 EKX54039.1 - 0.0037 17.2 0.1 0.74 9.8 0.0 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand CCD48 PF15799.5 EKX54039.1 - 0.041 12.2 0.0 0.041 12.2 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 GDI PF00996.18 EKX54040.1 - 7.3e-192 637.7 0.0 8.3e-192 637.5 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Fcf2 PF08698.11 EKX54041.1 - 4.8e-07 30.1 0.3 1.3e-06 28.7 0.3 1.7 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing HEAT PF02985.22 EKX54042.1 - 5.1e-11 41.8 0.1 0.72 10.3 0.0 6.5 6 0 0 6 6 6 3 HEAT repeat Vac14_Fab1_bd PF12755.7 EKX54042.1 - 2.2e-09 37.8 0.2 0.002 18.7 0.0 4.5 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EKX54042.1 - 1.7e-07 31.6 7.0 0.0053 17.2 0.0 6.4 6 1 1 7 7 7 1 HEAT-like repeat CLASP_N PF12348.8 EKX54042.1 - 1e-06 28.5 1.1 0.00011 21.9 0.1 2.8 3 0 0 3 3 3 1 CLASP N terminal HEAT_2 PF13646.6 EKX54042.1 - 0.0024 18.2 14.5 0.67 10.4 0.1 6.0 4 2 3 7 7 7 2 HEAT repeats BP28CT PF08146.12 EKX54042.1 - 0.009 15.9 2.0 0.037 13.9 0.1 2.9 2 1 0 2 2 2 1 BP28CT (NUC211) domain Dopey_N PF04118.14 EKX54042.1 - 0.026 13.7 0.6 0.28 10.3 0.0 2.7 2 2 0 2 2 2 0 Dopey, N-terminal WDCP PF15390.6 EKX54042.1 - 0.54 8.6 17.7 0.85 7.9 17.7 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family PPR PF01535.20 EKX54044.1 - 1.9e-05 24.6 4.1 0.0036 17.4 0.2 3.4 3 0 0 3 3 3 1 PPR repeat PPR_2 PF13041.6 EKX54044.1 - 7.9e-05 22.8 2.3 0.0016 18.6 0.1 3.1 3 0 0 3 3 3 1 PPR repeat family PPR_1 PF12854.7 EKX54044.1 - 0.00014 21.5 0.7 0.0004 20.0 0.1 2.1 3 0 0 3 3 3 1 PPR repeat DUF3787 PF12655.7 EKX54044.1 - 0.31 11.0 0.1 0.31 11.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3787) Peptidase_S41 PF03572.18 EKX54045.1 - 3.6e-42 143.7 0.1 6.1e-42 143.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 EKX54045.1 - 1.7e-09 37.4 0.1 4e-09 36.2 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX54045.1 - 9.3e-09 35.5 0.5 1.8e-08 34.5 0.5 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX54045.1 - 0.00016 21.9 0.1 0.00035 20.9 0.1 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 EKX54045.1 - 0.017 15.5 0.0 0.059 13.7 0.0 1.9 2 0 0 2 2 2 0 GRASP55/65 PDZ-like domain Tricorn_PDZ PF14685.6 EKX54045.1 - 0.092 12.7 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain Ras PF00071.22 EKX54045.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Ras family NIBRIN_BRCT_II PF16508.5 EKX54045.1 - 0.17 12.2 0.1 1.3 9.3 0.0 2.2 1 1 1 2 2 2 0 Second BRCT domain on Nijmegen syndrome breakage protein Trypsin_2 PF13365.6 EKX54046.1 - 3.1e-27 96.3 3.3 4.9e-27 95.7 3.3 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EKX54046.1 - 2.5e-10 40.6 0.8 3.8e-10 40.0 0.8 1.2 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 EKX54046.1 - 2.1e-09 37.1 0.0 4.1e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX54046.1 - 1.7e-05 25.1 0.2 4.8e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX54046.1 - 0.002 18.5 0.3 0.0048 17.2 0.0 1.8 2 0 0 2 2 2 1 PDZ domain Peptidase_S32 PF05579.13 EKX54046.1 - 0.011 15.0 4.6 0.17 11.1 2.0 2.1 1 1 1 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Peptidase_S7 PF00949.21 EKX54046.1 - 0.12 12.2 1.0 0.29 10.9 1.0 1.6 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Ufd2P_core PF10408.9 EKX54047.1 - 9.3e-44 150.1 0.2 9.3e-44 150.1 0.2 1.7 2 1 0 2 2 1 1 Ubiquitin elongating factor core U-box PF04564.15 EKX54047.1 - 3e-13 49.8 0.3 1.7e-10 40.9 0.0 2.6 2 0 0 2 2 2 1 U-box domain SDA1 PF05285.12 EKX54047.1 - 0.1 12.0 10.3 0.2 11.1 10.3 1.4 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 EKX54047.1 - 0.34 10.0 13.1 0.57 9.3 13.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RNA_pol_3_Rpc31 PF11705.8 EKX54047.1 - 0.37 11.0 14.1 0.66 10.2 14.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RPN2_C PF18004.1 EKX54047.1 - 0.59 10.0 3.4 1.2 9.0 3.4 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Nop14 PF04147.12 EKX54047.1 - 1.1 7.3 16.9 1.7 6.8 16.9 1.1 1 0 0 1 1 1 0 Nop14-like family Tub_N PF16322.5 EKX54047.1 - 1.7 9.0 12.5 0.3 11.4 6.9 2.1 2 0 0 2 2 2 0 Tubby N-terminal TFB6 PF17110.5 EKX54047.1 - 2.1 8.1 5.8 5.9 6.6 5.8 1.7 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Sporozoite_P67 PF05642.11 EKX54047.1 - 3.1 5.8 5.2 10 4.0 4.7 1.8 2 0 0 2 2 2 0 Sporozoite P67 surface antigen RXT2_N PF08595.11 EKX54047.1 - 4 7.4 7.9 9.5 6.2 7.9 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 EKX54047.1 - 4.5 6.5 14.5 8.3 5.6 14.5 1.3 1 0 0 1 1 1 0 NOA36 protein Pes-10 PF07149.11 EKX54047.1 - 5.1 6.0 18.9 11 5.0 14.9 2.4 2 0 0 2 2 2 0 Pes-10 BUD22 PF09073.10 EKX54047.1 - 7.1 5.8 13.0 13 5.0 13.0 1.3 1 0 0 1 1 1 0 BUD22 FAM176 PF14851.6 EKX54047.1 - 8.4 6.1 10.0 6.5 6.4 6.8 2.3 2 0 0 2 2 2 0 FAM176 family zn-ribbon_14 PF16503.5 EKX54047.1 - 9.2 5.9 6.4 2.3 7.8 1.7 2.4 3 0 0 3 3 3 0 Zinc-ribbon DUF4637 PF15470.6 EKX54047.1 - 9.9 5.9 10.2 25 4.6 10.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) PDZ_6 PF17820.1 EKX54048.1 - 8.1e-07 28.8 0.0 1.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX54048.1 - 2.9e-06 27.5 0.1 4.3e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX54048.1 - 0.00035 20.8 0.0 0.00054 20.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain LRR_8 PF13855.6 EKX54050.1 - 7.3e-27 92.9 9.0 1.4e-11 44.0 0.2 3.4 2 1 1 4 4 4 3 Leucine rich repeat LRR_5 PF13306.6 EKX54050.1 - 3.2e-12 46.5 0.4 3e-11 43.4 0.0 2.3 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) LRR_4 PF12799.7 EKX54050.1 - 7.5e-12 45.3 10.6 0.0045 17.4 3.1 3.5 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX54050.1 - 1.8e-05 24.7 17.8 0.2 12.3 0.5 7.1 7 1 1 8 8 8 3 Leucine Rich Repeat Ephrin_rec_like PF07699.13 EKX54050.1 - 2.6e-05 23.9 9.1 2.6e-05 23.9 9.1 2.4 2 1 0 2 2 2 1 Putative ephrin-receptor like LRR_9 PF14580.6 EKX54050.1 - 0.0012 18.4 0.6 0.09 12.3 0.3 2.1 1 1 2 3 3 3 3 Leucine-rich repeat Methyltransf_24 PF13578.6 EKX54055.1 - 0.00019 22.4 0.1 0.00045 21.2 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain C2 PF00168.30 EKX54056.1 - 5.9e-07 29.7 0.0 1e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain Wyosine_form PF08608.12 EKX54057.1 - 0.12 12.7 0.2 0.84 10.0 0.0 2.2 2 0 0 2 2 2 0 Wyosine base formation Img2 PF05046.14 EKX54061.1 - 1.9e-18 66.5 0.1 3.2e-18 65.8 0.1 1.4 2 0 0 2 2 2 1 Mitochondrial large subunit ribosomal protein (Img2) CM_2 PF01817.21 EKX54062.1 - 0.0062 16.9 0.8 1.9 8.9 0.1 2.7 2 1 0 2 2 2 2 Chorismate mutase type II Acetyltransf_1 PF00583.25 EKX54063.1 - 1.1e-13 51.4 0.1 1.5e-13 51.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EKX54063.1 - 2.1e-09 37.4 0.1 2.7e-09 37.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EKX54063.1 - 4.9e-09 36.5 0.3 8.2e-09 35.8 0.2 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EKX54063.1 - 3.1e-08 33.5 0.0 4.9e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EKX54063.1 - 0.0014 18.7 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EKX54063.1 - 0.0038 17.4 0.3 0.0057 16.8 0.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AJAP1_PANP_C PF15298.6 EKX54064.1 - 0.042 14.1 5.6 0.072 13.3 5.6 1.4 1 0 0 1 1 1 0 AJAP1/PANP C-terminus DUF829 PF05705.14 EKX54064.1 - 0.13 12.1 0.4 0.16 11.8 0.4 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) FSA_C PF10479.9 EKX54064.1 - 1.2 7.2 8.2 1.6 6.8 8.2 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus YqfQ PF14181.6 EKX54064.1 - 3.3 7.9 9.6 0.99 9.6 5.9 1.8 1 1 1 2 2 2 0 YqfQ-like protein SRP54 PF00448.22 EKX54065.1 - 1.6e-75 253.0 0.4 3.7e-75 251.9 0.1 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EKX54065.1 - 5.7e-30 103.9 3.9 5.7e-30 103.9 3.9 3.4 3 0 0 3 3 3 1 Signal peptide binding domain SRP54_N PF02881.19 EKX54065.1 - 1.7e-20 73.0 1.6 4.7e-20 71.6 1.6 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 EKX54065.1 - 3.7e-06 27.2 0.1 1.6e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EKX54065.1 - 3.8e-05 24.1 0.2 0.00017 22.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EKX54065.1 - 6e-05 23.5 0.0 0.00014 22.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 EKX54065.1 - 0.00019 21.1 2.5 0.0063 16.1 1.0 3.2 3 1 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 EKX54065.1 - 0.00029 20.3 0.4 0.12 11.8 0.4 2.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Zeta_toxin PF06414.12 EKX54065.1 - 0.0026 17.1 0.1 0.029 13.7 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 EKX54065.1 - 0.0046 17.2 0.1 0.017 15.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EKX54065.1 - 0.0082 16.2 0.6 0.1 12.7 0.4 2.9 3 1 0 3 3 3 1 50S ribosome-binding GTPase ResIII PF04851.15 EKX54065.1 - 0.021 14.8 0.1 0.049 13.6 0.1 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2209 PF09974.9 EKX54065.1 - 0.083 13.2 0.2 0.29 11.5 0.2 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) RelA_SpoT PF04607.17 EKX54065.1 - 0.12 12.7 0.1 0.32 11.3 0.1 1.7 2 0 0 2 2 2 0 Region found in RelA / SpoT proteins AAA PF00004.29 EKX54065.1 - 0.83 10.1 3.2 3.9 7.9 0.2 3.2 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) STI1 PF17830.1 EKX54065.1 - 1.3 9.0 10.0 0.073 13.0 2.5 2.9 3 0 0 3 3 2 0 STI1 domain CCDC53 PF10152.9 EKX54066.1 - 1.9e-42 145.3 20.2 2.5e-41 141.6 20.2 2.0 1 1 0 1 1 1 1 Subunit CCDC53 of WASH complex Spt20 PF12090.8 EKX54066.1 - 1.5e-06 28.0 19.6 1.7e-06 27.9 19.6 1.2 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 EKX54066.1 - 3.3e-05 24.1 19.8 3.5e-05 24.0 19.8 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit MMR1 PF08505.10 EKX54066.1 - 0.00043 20.7 9.4 0.00051 20.4 9.4 1.1 1 0 0 1 1 1 1 Mitochondrial Myo2 receptor-related protein ANAPC_CDC26 PF10471.9 EKX54066.1 - 0.0013 19.5 20.5 0.0025 18.6 20.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 DUF4834 PF16118.5 EKX54066.1 - 0.0051 17.8 5.7 0.0081 17.1 5.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) SKA1 PF07160.12 EKX54066.1 - 0.0056 16.6 9.5 0.0073 16.2 9.5 1.2 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 TMEM51 PF15345.6 EKX54066.1 - 0.0064 16.4 7.1 0.0097 15.8 7.1 1.3 1 0 0 1 1 1 1 Transmembrane protein 51 LIM_bind PF01803.16 EKX54066.1 - 0.0084 15.7 5.8 0.011 15.3 5.8 1.3 1 0 0 1 1 1 1 LIM-domain binding protein UPF0524 PF15823.5 EKX54066.1 - 0.01 15.3 1.5 0.014 14.8 1.5 1.3 1 0 0 1 1 1 0 UPF0524 of C3orf70 TERB2 PF15101.6 EKX54066.1 - 0.012 15.7 11.9 0.016 15.3 11.9 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DDHD PF02862.17 EKX54066.1 - 0.014 15.6 4.0 0.015 15.5 4.0 1.1 1 0 0 1 1 1 0 DDHD domain DUF2722 PF10846.8 EKX54066.1 - 0.018 14.0 25.0 0.026 13.5 25.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Mucin PF01456.17 EKX54066.1 - 0.023 14.7 5.2 0.034 14.1 5.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein ALMT PF11744.8 EKX54066.1 - 0.033 13.0 4.4 0.04 12.8 4.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 EKX54066.1 - 0.034 12.9 7.0 0.042 12.6 7.0 1.2 1 0 0 1 1 1 0 Presenilin Activator_LAG-3 PF11498.8 EKX54066.1 - 0.034 13.1 26.1 0.057 12.4 26.1 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 eIF-3_zeta PF05091.12 EKX54066.1 - 0.042 12.8 6.8 0.045 12.7 6.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Neur_chan_memb PF02932.16 EKX54066.1 - 0.064 13.3 4.4 0.076 13.1 4.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.9 EKX54066.1 - 0.078 11.2 19.0 0.085 11.1 19.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ctr PF04145.15 EKX54066.1 - 0.081 13.5 1.6 0.12 13.0 1.6 1.4 1 0 0 1 1 1 0 Ctr copper transporter family GREB1 PF15782.5 EKX54066.1 - 0.085 10.0 9.4 0.088 9.9 9.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF702 PF05142.12 EKX54066.1 - 0.099 13.1 5.9 0.14 12.6 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) SpoIIP PF07454.11 EKX54066.1 - 0.11 12.0 5.8 0.14 11.6 5.8 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF4407 PF14362.6 EKX54066.1 - 0.19 11.0 5.7 0.24 10.7 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Hid1 PF12722.7 EKX54066.1 - 0.19 9.8 6.4 0.19 9.8 6.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CPSF100_C PF13299.6 EKX54066.1 - 0.21 11.8 6.3 0.31 11.2 6.3 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Menin PF05053.13 EKX54066.1 - 0.28 9.5 5.0 0.31 9.4 5.0 1.1 1 0 0 1 1 1 0 Menin V_ATPase_I PF01496.19 EKX54066.1 - 0.3 8.9 6.8 0.35 8.7 6.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mcm10 PF09332.11 EKX54066.1 - 0.38 10.1 10.7 0.48 9.8 10.7 1.2 1 0 0 1 1 1 0 Mcm10 replication factor MscS_TM PF12794.7 EKX54066.1 - 0.4 9.5 3.8 0.56 9.0 3.8 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 OATP PF03137.20 EKX54066.1 - 0.41 8.9 2.1 0.51 8.6 2.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Orf78 PF06024.12 EKX54066.1 - 0.5 10.7 3.5 0.9 9.9 3.5 1.4 1 0 0 1 1 1 0 Orf78 (ac78) BRF1 PF07741.13 EKX54066.1 - 0.51 10.7 6.7 1.1 9.6 6.7 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Lin-8 PF03353.15 EKX54066.1 - 0.57 9.7 11.1 0.76 9.3 11.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Folate_carrier PF01770.18 EKX54066.1 - 0.67 8.6 4.7 0.89 8.2 4.7 1.1 1 0 0 1 1 1 0 Reduced folate carrier Band_3_cyto PF07565.13 EKX54066.1 - 0.8 9.5 8.6 1.1 9.0 8.6 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Ndc1_Nup PF09531.10 EKX54066.1 - 0.86 8.2 14.9 1 7.9 14.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MPM1 PF17234.2 EKX54066.1 - 1 9.6 10.0 1.7 8.9 10.0 1.3 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Rrn6 PF10214.9 EKX54066.1 - 1.5 7.2 15.9 1.6 7.1 15.9 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Roughex PF06020.11 EKX54066.1 - 1.8 7.6 14.2 2.8 6.9 14.2 1.3 1 0 0 1 1 1 0 Drosophila roughex protein CLN3 PF02487.17 EKX54066.1 - 4.9 6.1 5.9 6.6 5.7 5.9 1.2 1 0 0 1 1 1 0 CLN3 protein FAM70 PF14967.6 EKX54066.1 - 9.8 5.5 7.2 12 5.2 7.2 1.3 1 0 0 1 1 1 0 FAM70 protein Enkurin PF13864.6 EKX54067.1 - 1.1e-22 80.2 1.3 1.1e-22 80.2 1.3 2.5 2 1 0 2 2 2 1 Calmodulin-binding Glyco_hyd_65N_2 PF14498.6 EKX54068.1 - 2.4e-26 93.0 0.9 7.2e-15 55.5 0.1 2.6 3 0 0 3 3 3 2 Glycosyl hydrolase family 65, N-terminal domain PAN_4 PF14295.6 EKX54068.1 - 4.6e-09 36.0 3.8 1.6e-08 34.4 3.8 2.0 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 EKX54068.1 - 2.7e-06 27.2 3.8 2.7e-06 27.2 3.8 3.3 3 0 0 3 3 3 1 PAN domain PAN_2 PF08276.11 EKX54068.1 - 1.2 9.3 11.1 0.97 9.6 8.0 2.5 2 1 0 2 2 2 0 PAN-like domain SMK-1 PF04802.15 EKX54069.1 - 1.8e-60 204.0 4.3 8.9e-60 201.8 1.6 2.7 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 Transposase_24 PF03004.14 EKX54069.1 - 0.058 13.5 0.2 0.12 12.5 0.2 1.5 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) DUF2681 PF10883.8 EKX54069.1 - 0.11 13.0 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) RRM_1 PF00076.22 EKX54070.1 - 3.3e-24 84.5 0.0 3.7e-24 84.3 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EKX54070.1 - 0.00042 20.2 0.0 0.00055 19.9 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EKX54070.1 - 0.0032 17.6 0.0 0.0051 16.9 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif Nup35_RRM PF05172.13 EKX54070.1 - 0.0077 16.2 0.0 0.0097 15.8 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Ribosomal_L18A PF01775.17 EKX54070.1 - 0.042 14.0 0.0 0.049 13.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A KH_1 PF00013.29 EKX54071.1 - 5.5e-10 38.9 1.7 8.2e-10 38.4 1.7 1.3 1 1 0 1 1 1 1 KH domain Sod_Ni PF09055.11 EKX54072.1 - 0.086 13.4 0.5 0.22 12.1 0.2 1.8 1 1 0 1 1 1 0 Nickel-containing superoxide dismutase TPT PF03151.16 EKX54073.1 - 2.2e-12 47.0 20.0 2.9e-12 46.5 20.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family YiaAB PF05360.14 EKX54073.1 - 0.017 15.4 1.6 0.017 15.4 1.6 2.7 3 0 0 3 3 3 0 yiaA/B two helix domain Phage_holin_2_4 PF16082.5 EKX54073.1 - 0.019 14.7 0.0 0.058 13.1 0.0 1.9 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Oxidored_q5_N PF01059.17 EKX54073.1 - 1.3 9.2 12.1 0.047 13.8 3.3 2.9 2 2 1 3 3 3 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus Ribosomal_L37ae PF01780.19 EKX54074.1 - 9.5e-43 144.2 8.8 1.1e-42 144.0 8.8 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Lar_restr_allev PF14354.6 EKX54074.1 - 0.00082 19.7 1.1 0.0013 19.1 1.1 1.3 1 0 0 1 1 1 1 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 EKX54074.1 - 0.026 14.5 5.2 0.044 13.8 5.2 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-RING_13 PF17977.1 EKX54074.1 - 0.061 13.5 3.5 0.089 12.9 3.5 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2175 PF09943.9 EKX54074.1 - 0.092 13.0 1.9 6.5 7.1 0.2 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) YyzF PF14116.6 EKX54074.1 - 0.44 10.6 0.2 0.44 10.6 0.2 1.9 2 0 0 2 2 2 0 YyzF-like protein zf-ribbon_3 PF13248.6 EKX54074.1 - 0.61 9.6 5.3 3.2 7.3 5.2 2.0 1 1 1 2 2 2 0 zinc-ribbon domain Nup192 PF11894.8 EKX54075.1 - 8.3e-12 43.2 10.4 5.5e-07 27.2 0.0 4.4 5 0 0 5 5 5 4 Nuclear pore complex scaffold, nucleoporins 186/192/205 CENP-K PF11802.8 EKX54075.1 - 0.017 14.7 0.1 0.073 12.6 0.1 2.0 2 0 0 2 2 2 0 Centromere-associated protein K Ribosomal_60s PF00428.19 EKX54075.1 - 0.096 13.3 7.4 0.33 11.6 7.4 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein SmpB PF01668.18 EKX54076.1 - 1.5e-48 164.3 2.4 1.9e-48 164.0 2.4 1.1 1 0 0 1 1 1 1 SmpB protein BLOC1_2 PF10046.9 EKX54077.1 - 1.3e-20 73.5 13.0 1.4e-20 73.3 13.0 1.0 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 EKX54077.1 - 0.0003 21.0 4.3 0.00044 20.4 3.5 1.7 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) Dor1 PF04124.12 EKX54077.1 - 0.0057 15.4 2.6 0.0063 15.3 2.6 1.1 1 0 0 1 1 1 1 Dor1-like family MCPsignal PF00015.21 EKX54077.1 - 0.0063 16.3 1.1 0.0074 16.1 1.1 1.1 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Sec34 PF04136.15 EKX54077.1 - 0.0068 16.3 3.8 0.0087 15.9 3.8 1.3 1 0 0 1 1 1 1 Sec34-like family DHR10 PF18595.1 EKX54077.1 - 0.011 15.8 4.6 0.011 15.8 4.6 1.4 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Phage_GP20 PF06810.11 EKX54077.1 - 0.014 15.2 7.4 0.018 14.8 7.4 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 FliJ PF02050.16 EKX54077.1 - 0.02 15.1 2.0 0.16 12.2 0.2 2.0 1 1 1 2 2 2 0 Flagellar FliJ protein Mce4_CUP1 PF11887.8 EKX54077.1 - 0.038 13.5 2.7 0.065 12.7 2.4 1.4 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF4635 PF15466.6 EKX54077.1 - 0.04 13.4 0.9 0.048 13.2 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) MtrB PF05440.12 EKX54077.1 - 0.043 14.2 1.4 2.3 8.7 0.1 2.2 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B NPV_P10 PF05531.12 EKX54077.1 - 0.066 13.7 2.8 0.096 13.2 2.8 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 EKX54077.1 - 0.072 13.1 4.8 0.098 12.7 4.8 1.3 1 0 0 1 1 1 0 Laminin Domain II Nsp1_C PF05064.13 EKX54077.1 - 0.073 12.9 5.6 0.11 12.3 4.3 2.0 1 1 1 2 2 2 0 Nsp1-like C-terminal region Flagellin_N PF00669.20 EKX54077.1 - 0.092 12.8 3.0 0.11 12.6 3.0 1.2 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region Lipoprotein_20 PF13942.6 EKX54077.1 - 0.1 12.5 4.2 0.12 12.2 3.8 1.4 1 1 0 1 1 1 0 YfhG lipoprotein OmpH PF03938.14 EKX54077.1 - 0.12 12.7 7.3 0.16 12.3 7.3 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Spectrin PF00435.21 EKX54077.1 - 0.18 12.3 5.2 0.27 11.7 4.5 1.6 1 1 0 1 1 1 0 Spectrin repeat DASH_Dam1 PF08653.10 EKX54077.1 - 0.19 11.6 3.1 4.6 7.1 0.3 2.4 1 1 1 2 2 2 0 DASH complex subunit Dam1 PCRF PF03462.18 EKX54077.1 - 0.23 11.3 4.4 0.38 10.6 4.4 1.5 1 1 0 1 1 1 0 PCRF domain Tup_N PF08581.10 EKX54077.1 - 0.24 11.7 8.5 2.4 8.5 2.5 2.1 1 1 1 2 2 2 0 Tup N-terminal BPS1 PF05633.11 EKX54077.1 - 0.28 10.1 4.0 0.29 10.1 2.1 1.7 1 1 1 2 2 2 0 Protein BYPASS1-related Prefoldin PF02996.17 EKX54077.1 - 0.33 10.9 8.0 0.69 9.8 0.5 2.4 1 1 2 3 3 3 0 Prefoldin subunit Uso1_p115_C PF04871.13 EKX54077.1 - 0.37 11.2 11.7 0.5 10.7 11.7 1.4 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region CLZ PF16526.5 EKX54077.1 - 0.39 11.1 6.9 1.5 9.2 2.2 2.3 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CRR7 PF12095.8 EKX54077.1 - 0.39 11.2 5.1 0.71 10.4 4.9 1.5 1 1 0 1 1 1 0 Protein CHLORORESPIRATORY REDUCTION 7 LMBR1 PF04791.16 EKX54077.1 - 0.43 9.4 2.5 0.44 9.4 2.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3450 PF11932.8 EKX54077.1 - 0.46 9.8 7.1 0.55 9.5 4.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 EKX54077.1 - 0.62 10.1 4.7 1.3 9.1 4.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) RRP36 PF06102.12 EKX54077.1 - 0.67 9.9 5.9 0.84 9.6 5.9 1.1 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 Syntaxin-6_N PF09177.11 EKX54077.1 - 0.77 10.3 6.3 3.9 8.1 6.3 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal TMPIT PF07851.13 EKX54077.1 - 1.1 8.4 5.2 1.2 8.3 5.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein FliD_N PF02465.18 EKX54077.1 - 1.5 9.6 7.1 7 7.4 7.1 1.9 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Fib_alpha PF08702.10 EKX54077.1 - 1.7 8.8 7.6 4.2 7.6 1.0 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DASH_Dad3 PF08656.10 EKX54077.1 - 1.8 8.7 8.5 3.5 7.8 4.7 2.3 1 1 1 2 2 2 0 DASH complex subunit Dad3 XhlA PF10779.9 EKX54077.1 - 6.2 7.1 9.9 4.1 7.7 5.4 2.2 1 1 1 2 2 2 0 Haemolysin XhlA DUF1445 PF07286.12 EKX54078.1 - 4.9e-56 188.6 0.0 6.9e-56 188.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) DUF5610 PF18433.1 EKX54079.1 - 0.0038 17.7 1.0 0.0038 17.7 1.0 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF5610) Rx_N PF18052.1 EKX54079.1 - 0.061 13.6 1.5 0.27 11.5 1.5 2.0 1 1 0 1 1 1 0 Rx N-terminal domain SPOUT_MTase PF02590.17 EKX54079.1 - 0.16 12.0 0.4 0.2 11.6 0.4 1.2 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase GET2 PF08690.10 EKX54079.1 - 0.66 9.6 7.0 0.72 9.5 7.0 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 NOA36 PF06524.12 EKX54079.1 - 5 6.4 8.5 8 5.7 8.5 1.3 1 0 0 1 1 1 0 NOA36 protein DUF2514 PF10721.9 EKX54080.1 - 0.63 10.1 4.9 0.38 10.8 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) Histone PF00125.24 EKX54081.1 - 1.1e-51 174.6 1.4 1.2e-51 174.5 1.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EKX54081.1 - 0.00013 22.0 0.1 0.00025 21.1 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EKX54081.1 - 0.00022 21.8 0.8 0.00026 21.6 0.8 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 EKX54081.1 - 0.00089 19.6 0.0 0.0014 19.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein Sirohm_synth_M PF14824.6 EKX54081.1 - 0.5 9.9 2.2 2.9 7.4 0.2 2.5 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central Cwf_Cwc_15 PF04889.12 EKX54086.1 - 1.7e-59 201.6 20.1 1.1e-58 198.9 20.1 1.8 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein MFAP1 PF06991.11 EKX54086.1 - 0.0025 17.7 19.2 0.004 17.0 19.2 1.2 1 0 0 1 1 1 1 Microfibril-associated/Pre-mRNA processing ALMT PF11744.8 EKX54086.1 - 9.4 4.9 7.2 12 4.5 7.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter MIP PF00230.20 EKX54087.1 - 1.4e-44 152.5 14.6 1.9e-44 152.1 14.6 1.1 1 0 0 1 1 1 1 Major intrinsic protein Lycopene_cycl PF05834.12 EKX54090.1 - 3e-62 210.9 1.1 1.9e-47 162.2 0.0 2.7 2 1 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EKX54090.1 - 0.0011 18.3 0.3 0.0044 16.3 0.3 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EKX54090.1 - 0.0025 17.5 0.5 0.18 11.3 0.0 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase QRPTase_C PF01729.19 EKX54090.1 - 0.028 14.2 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain DUF2967 PF11179.8 EKX54093.1 - 2.9 5.9 5.0 5.2 5.0 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Pkinase PF00069.25 EKX54094.1 - 1.9e-61 207.8 0.0 2.5e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX54094.1 - 1.8e-39 135.6 0.0 2.2e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX54094.1 - 9.7e-05 21.8 0.0 0.00014 21.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EKX54094.1 - 0.0002 20.3 0.2 0.00033 19.5 0.1 1.2 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EKX54094.1 - 0.00056 19.0 0.5 0.00072 18.6 0.5 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EKX54094.1 - 0.036 13.4 0.5 0.085 12.2 0.5 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FlxA PF14282.6 EKX54095.1 - 0.011 15.7 8.3 0.011 15.7 8.3 5.9 2 2 0 4 4 4 0 FlxA-like protein ATG16 PF08614.11 EKX54095.1 - 5.8 7.1 95.2 37 4.4 21.3 5.6 1 1 4 5 5 5 0 Autophagy protein 16 (ATG16) Cellulase PF00150.18 EKX54097.1 - 4.6e-15 55.8 0.8 6.4e-15 55.3 0.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CSD PF00313.22 EKX54100.1 - 5.3e-29 99.9 0.7 8.2e-29 99.3 0.7 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 EKX54100.1 - 0.0015 18.2 0.1 0.0032 17.1 0.1 1.6 1 0 0 1 1 1 1 Ribonuclease B OB domain Mito_carr PF00153.27 EKX54101.1 - 8.7e-29 99.3 5.8 8.3e-15 54.5 0.1 2.8 3 0 0 3 3 3 2 Mitochondrial carrier protein DUF3767 PF12597.8 EKX54101.1 - 0.17 11.8 0.0 0.47 10.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) BRE PF06113.12 EKX54102.1 - 8.6e-18 64.2 0.5 2.1e-11 43.2 0.1 2.1 1 1 1 2 2 2 2 Brain and reproductive organ-expressed protein (BRE) Sec63 PF02889.16 EKX54104.1 - 1.3e-166 552.1 0.4 1.8e-87 292.7 0.2 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EKX54104.1 - 2.2e-52 177.4 0.5 1.4e-26 93.4 0.1 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 EKX54104.1 - 1.7e-35 121.5 1.9 1.1e-34 118.9 2.2 2.4 2 0 0 2 2 2 1 N-terminal helicase PWI domain ResIII PF04851.15 EKX54104.1 - 1.3e-24 87.2 0.2 1.2e-10 41.7 0.0 3.3 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EKX54104.1 - 6.2e-08 33.0 0.1 1.1e-06 28.9 0.0 3.2 3 1 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EKX54104.1 - 1.2e-07 32.1 0.0 0.019 15.2 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EKX54104.1 - 7.6e-07 29.0 0.0 0.045 13.5 0.0 3.2 2 1 1 3 3 3 2 AAA domain T2SSE PF00437.20 EKX54104.1 - 9.3e-06 24.9 0.0 0.011 14.9 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein PhoH PF02562.16 EKX54104.1 - 0.0018 17.8 0.0 0.084 12.3 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_11 PF13086.6 EKX54104.1 - 0.01 15.7 6.0 2 8.1 0.0 4.3 3 1 0 3 3 3 0 AAA domain AAA_16 PF13191.6 EKX54104.1 - 0.064 13.6 0.1 15 5.9 0.0 3.6 3 1 0 3 3 3 0 AAA ATPase domain CDPS PF16715.5 EKX54104.1 - 0.12 12.0 5.3 6 6.5 1.1 3.0 3 0 0 3 3 3 0 Cyclodipeptide synthase AAA_7 PF12775.7 EKX54104.1 - 0.13 11.7 0.1 3.8 7.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region UvrD-helicase PF00580.21 EKX54104.1 - 0.59 9.6 2.6 24 4.3 0.0 3.5 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain zf-PARP PF00645.18 EKX54105.1 - 2.7e-17 63.4 0.0 3.6e-08 34.2 0.0 2.5 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region CBM-like PF14683.6 EKX54106.1 - 1.3e-05 25.1 0.5 1.5 8.7 0.0 5.0 4 0 0 4 4 4 2 Polysaccharide lyase family 4, domain III DNA_pol_B_N PF18094.1 EKX54106.1 - 0.0024 18.4 0.2 13 6.4 0.0 4.0 4 0 0 4 4 4 2 DNA polymerase beta N-terminal domain PSI PF01437.25 EKX54107.1 - 0.064 13.8 2.6 0.14 12.7 2.6 1.6 1 0 0 1 1 1 0 Plexin repeat ALMT PF11744.8 EKX54108.1 - 1.5 7.6 12.1 2.3 7.0 12.1 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Atg14 PF10186.9 EKX54108.1 - 1.7 7.6 11.4 2.4 7.1 11.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sod_Fe_C PF02777.18 EKX54109.1 - 5e-40 135.8 0.4 9.8e-40 134.9 0.4 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EKX54109.1 - 1.2e-31 109.0 0.3 2.4e-31 108.0 0.3 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain FH2 PF02181.23 EKX54110.1 - 8.5e-53 179.8 0.0 1e-52 179.5 0.0 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain Zw10 PF06248.13 EKX54111.1 - 0.00015 20.5 7.5 0.00099 17.8 0.0 2.5 3 0 0 3 3 3 2 Centromere/kinetochore Zw10 DUF641 PF04859.12 EKX54111.1 - 0.3 11.4 10.9 4.7 7.6 3.1 2.8 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DUF2367 PF10164.9 EKX54113.1 - 9 6.9 8.5 14 6.3 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) Methyltransf_31 PF13847.6 EKX54114.1 - 2.2e-26 92.5 0.0 3.3e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX54114.1 - 9.9e-25 87.0 0.0 1.8e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX54114.1 - 3.2e-24 85.5 0.0 5.2e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX54114.1 - 1.4e-18 67.3 0.0 2.2e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX54114.1 - 1.2e-16 60.8 0.0 1.8e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EKX54114.1 - 9.1e-16 58.4 0.0 1.7e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EKX54114.1 - 4.2e-12 45.9 0.0 5.5e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.16 EKX54114.1 - 6.8e-11 41.4 0.0 1.2e-10 40.6 0.0 1.3 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.19 EKX54114.1 - 2e-06 27.7 0.0 2.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 EKX54114.1 - 4.2e-06 26.3 0.0 0.0013 18.2 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase FtsJ PF01728.19 EKX54114.1 - 1.7e-05 25.0 0.0 9e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase TehB PF03848.14 EKX54114.1 - 2.8e-05 23.6 0.0 4.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.14 EKX54114.1 - 0.00018 21.1 0.0 0.00046 19.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 EKX54114.1 - 0.0011 18.2 0.0 0.003 16.7 0.0 1.7 2 0 0 2 2 2 1 DREV methyltransferase MetW PF07021.12 EKX54114.1 - 0.0011 18.6 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.6 EKX54114.1 - 0.0014 19.7 0.0 0.0022 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EKX54114.1 - 0.0014 18.7 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 EKX54114.1 - 0.0036 17.3 0.0 0.0086 16.1 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_8 PF05148.15 EKX54114.1 - 0.0073 16.2 0.0 0.015 15.1 0.0 1.6 1 1 0 1 1 1 1 Hypothetical methyltransferase NodS PF05401.11 EKX54114.1 - 0.042 13.4 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) NAS PF03059.16 EKX54114.1 - 0.12 11.6 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Nicotianamine synthase protein RrnaAD PF00398.20 EKX54114.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF1995 PF09353.10 EKX54115.1 - 2.7e-14 53.7 0.0 3.5e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) GNT-I PF03071.15 EKX54117.1 - 1.9e-34 119.2 1.4 2.2e-34 119.0 1.4 1.0 1 0 0 1 1 1 1 GNT-I family MGAT2 PF05060.14 EKX54117.1 - 0.0016 17.6 0.3 0.0016 17.5 0.3 1.0 1 0 0 1 1 1 1 N-acetylglucosaminyltransferase II (MGAT2) tRNA-synt_1 PF00133.22 EKX54118.1 - 2e-224 746.3 0.2 2.8e-224 745.9 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EKX54118.1 - 4.9e-20 72.0 0.0 1.2e-19 70.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EKX54118.1 - 1.6e-15 56.8 0.3 9.8e-05 21.3 0.1 4.8 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EKX54118.1 - 0.016 14.6 0.0 0.035 13.4 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain HTH_Tnp_Tc5 PF03221.16 EKX54119.1 - 2.1e-08 34.1 0.0 4.6e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_3 PF01381.22 EKX54119.1 - 0.00017 21.6 0.0 0.00057 19.9 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix Sigma70_r4 PF04545.16 EKX54119.1 - 0.00061 19.3 0.1 0.012 15.1 0.0 2.5 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_28 PF13518.6 EKX54119.1 - 0.0012 18.9 0.6 0.43 10.7 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_23 PF13384.6 EKX54119.1 - 0.0028 17.4 0.8 0.092 12.6 0.1 2.9 2 1 0 2 2 2 1 Homeodomain-like domain CENP-B_N PF04218.13 EKX54119.1 - 0.018 14.7 0.2 0.058 13.0 0.2 1.9 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain MarR_2 PF12802.7 EKX54119.1 - 0.029 14.3 0.0 0.083 12.8 0.0 1.8 1 0 0 1 1 1 0 MarR family HTH_38 PF13936.6 EKX54119.1 - 0.035 13.9 0.2 0.48 10.2 0.1 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain DUF268 PF03269.14 EKX54120.1 - 3.6e-09 36.7 0.0 5.9e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Caenorhabditis protein of unknown function, DUF268 EF-hand_1 PF00036.32 EKX54121.1 - 1.4e-28 96.3 11.4 0.00017 20.9 0.0 6.4 6 0 0 6 6 6 6 EF hand EF-hand_7 PF13499.6 EKX54121.1 - 7.2e-24 84.0 7.6 3.3e-08 33.9 0.1 4.0 3 1 2 5 5 5 5 EF-hand domain pair EF-hand_6 PF13405.6 EKX54121.1 - 5.9e-21 72.6 9.5 0.01 15.7 0.0 6.3 6 0 0 6 6 6 6 EF-hand domain EF-hand_5 PF13202.6 EKX54121.1 - 7.3e-17 60.0 11.1 0.079 12.5 0.0 6.3 6 0 0 6 6 6 6 EF hand EF-hand_8 PF13833.6 EKX54121.1 - 6.7e-15 54.7 11.0 5.2e-05 23.0 0.5 6.1 3 3 3 6 6 6 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX54121.1 - 1.5e-08 35.0 4.8 0.047 14.0 0.1 4.7 2 1 2 4 4 4 3 Secreted protein acidic and rich in cysteine Ca binding region DMP12 PF16779.5 EKX54121.1 - 0.0048 16.9 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 DNA-mimic protein EF-hand_4 PF12763.7 EKX54121.1 - 0.029 14.3 10.2 5.8 6.9 0.1 4.7 1 1 4 5 5 5 0 Cytoskeletal-regulatory complex EF hand Med9 PF07544.13 EKX54121.1 - 0.49 10.5 4.4 2.8 8.1 0.1 3.3 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 PKcGMP_CC PF16808.5 EKX54121.1 - 0.83 9.6 3.1 0.41 10.5 0.8 1.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PNPase PF03726.14 EKX54121.1 - 2.7 8.5 6.2 0.43 11.1 1.0 2.3 3 0 0 3 3 3 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF5058 PF16481.5 EKX54123.1 - 0.016 14.9 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5058) Spore_III_AB PF09548.10 EKX54123.1 - 0.038 14.1 0.0 0.91 9.6 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Sec1 PF00995.23 EKX54125.1 - 3.2e-09 36.6 0.0 3.1e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 Sec1 family TMF_DNA_bd PF12329.8 EKX54126.1 - 0.00069 19.6 0.6 0.0012 18.8 0.6 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 EKX54126.1 - 0.0076 16.5 0.2 0.015 15.5 0.2 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Spc29 PF17082.5 EKX54126.1 - 0.047 13.5 0.4 0.078 12.8 0.4 1.3 1 0 0 1 1 1 0 Spindle Pole Component 29 DivIC PF04977.15 EKX54126.1 - 0.3 10.9 0.7 0.53 10.1 0.7 1.3 1 0 0 1 1 1 0 Septum formation initiator PKcGMP_CC PF16808.5 EKX54126.1 - 0.84 9.5 3.4 0.62 10.0 0.4 2.1 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Ank PF00023.30 EKX54127.1 - 7.8e-17 60.9 0.0 2.2e-08 34.2 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EKX54127.1 - 4.9e-16 57.2 0.0 2.4e-08 33.6 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EKX54127.1 - 1.4e-15 57.4 0.0 3.1e-15 56.3 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX54127.1 - 7.4e-14 52.1 0.0 1.1e-06 29.1 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX54127.1 - 1.1e-12 47.8 0.0 2.3e-06 27.7 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) WD40 PF00400.32 EKX54128.1 - 2.6e-45 151.5 15.0 1.3e-07 32.2 0.5 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX54128.1 - 1.6e-16 60.3 0.0 0.094 13.0 0.0 5.9 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX54128.1 - 0.0002 20.5 0.0 1.5 7.7 0.0 3.7 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EKX54128.1 - 0.00069 19.5 0.0 0.039 13.8 0.0 2.7 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EKX54128.1 - 0.003 16.3 0.0 3 6.4 0.0 3.5 5 0 0 5 5 5 1 Nucleoporin Nup120/160 Nbas_N PF15492.6 EKX54128.1 - 0.021 14.2 0.1 13 5.0 0.0 3.6 1 1 3 4 4 4 0 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 EKX54128.1 - 0.052 12.9 0.0 31 3.8 0.0 3.4 3 1 1 4 4 4 0 WD40-like domain Arena_nucleocap PF00843.17 EKX54128.1 - 0.11 11.4 0.1 4.6 6.0 0.0 2.4 2 1 1 3 3 3 0 Arenavirus nucleocapsid N-terminal domain DUF2415 PF10313.9 EKX54128.1 - 0.33 10.9 1.0 24 4.9 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) GcpE PF04551.14 EKX54129.1 - 2.4e-152 507.1 0.0 2.8e-152 506.8 0.0 1.0 1 0 0 1 1 1 1 GcpE protein Thiamine_BP PF01910.17 EKX54129.1 - 0.1 12.5 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 Thiamine-binding protein Sgf11 PF08209.11 EKX54129.1 - 0.12 12.0 0.1 0.27 10.8 0.1 1.6 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) PAS_9 PF13426.7 EKX54130.1 - 6.7e-05 23.1 0.0 0.00018 21.7 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_11 PF14598.6 EKX54130.1 - 0.066 13.3 0.0 0.18 11.9 0.0 1.7 2 0 0 2 2 2 0 PAS domain DUF3079 PF11278.8 EKX54130.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3079) FIST PF08495.10 EKX54131.1 - 1.2e-21 77.5 0.0 4e-19 69.3 0.0 2.4 2 0 0 2 2 2 2 FIST N domain FIST_C PF10442.9 EKX54131.1 - 1.5e-12 47.6 0.1 2e-11 43.9 0.0 2.4 2 0 0 2 2 2 1 FIST C domain C2 PF00168.30 EKX54132.1 - 6.1e-15 55.4 0.0 7.9e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 C2 domain BOFC_N PF08977.10 EKX54132.1 - 0.053 13.5 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Bypass of Forespore C, N terminal ABC_tran PF00005.27 EKX54133.1 - 5.5e-34 117.6 0.0 1.1e-33 116.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EKX54133.1 - 1.6e-27 96.9 6.6 2.1e-27 96.5 6.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EKX54133.1 - 1.2e-09 38.0 0.0 1.1e-06 28.2 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EKX54133.1 - 0.00031 21.0 0.0 0.0045 17.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EKX54133.1 - 0.0006 20.2 0.1 0.0012 19.3 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EKX54133.1 - 0.0039 17.6 0.0 0.077 13.4 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EKX54133.1 - 0.0044 17.0 0.0 0.0089 16.0 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 EKX54133.1 - 0.0044 16.7 0.0 0.012 15.3 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EKX54133.1 - 0.0048 16.6 0.0 0.0099 15.6 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EKX54133.1 - 0.01 15.7 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 EKX54133.1 - 0.011 16.3 0.1 0.03 14.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_21 PF13304.6 EKX54133.1 - 0.016 15.0 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system IstB_IS21 PF01695.17 EKX54133.1 - 0.018 14.8 1.5 2.2 8.0 0.0 2.8 2 1 1 3 3 3 0 IstB-like ATP binding protein AAA_14 PF13173.6 EKX54133.1 - 0.036 14.1 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EKX54133.1 - 0.038 14.5 0.0 0.14 12.7 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 EKX54133.1 - 0.039 12.9 0.0 0.067 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_30 PF13604.6 EKX54133.1 - 0.039 13.7 0.0 0.12 12.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 EKX54133.1 - 0.042 13.5 0.0 0.096 12.3 0.0 1.6 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.14 EKX54133.1 - 0.047 13.7 0.0 0.59 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EKX54133.1 - 0.052 13.8 0.5 0.37 11.0 0.0 2.6 3 1 1 4 4 4 0 AAA domain DUF815 PF05673.13 EKX54133.1 - 0.06 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 EKX54133.1 - 0.098 12.7 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 EKX54133.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RhoGEF PF00621.20 EKX54134.1 - 8.8e-06 26.1 0.0 0.00031 21.0 0.0 2.9 2 0 0 2 2 2 1 RhoGEF domain Lipase_3 PF01764.25 EKX54134.1 - 0.00017 21.5 0.0 0.00041 20.2 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Pkinase PF00069.25 EKX54135.1 - 1e-27 97.1 0.0 1.6e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX54135.1 - 4.9e-27 94.9 0.0 1.5e-26 93.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX54135.1 - 0.0051 16.8 0.2 0.06 13.3 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX54135.1 - 0.2 10.4 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase RRM_1 PF00076.22 EKX54136.1 - 6.3e-13 48.4 0.0 2.2e-07 30.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_16 PF10294.9 EKX54137.1 - 8.6e-21 74.4 0.0 1e-20 74.2 0.0 1.0 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 EKX54137.1 - 4.8e-10 39.3 0.0 4.9e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EKX54137.1 - 1.6e-06 27.7 0.0 2.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EKX54137.1 - 1.2e-05 25.9 0.0 2.7e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX54137.1 - 0.0013 18.6 0.0 0.0017 18.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EKX54137.1 - 0.0059 16.4 0.0 0.0075 16.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_12 PF08242.12 EKX54137.1 - 0.0081 16.9 0.0 0.015 16.0 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX54137.1 - 0.013 16.2 0.1 0.024 15.3 0.0 1.6 2 1 0 2 2 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 EKX54137.1 - 0.015 15.0 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 RrnaAD PF00398.20 EKX54137.1 - 0.023 13.8 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.19 EKX54137.1 - 0.034 13.9 0.0 0.046 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EKX54137.1 - 0.059 13.2 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain HalOD2 PF18547.1 EKX54137.1 - 0.38 10.7 0.1 0.38 10.7 0.1 2.2 2 1 1 3 3 3 0 Halobacterial output domain 2 SOGA PF11365.8 EKX54138.1 - 0.094 13.9 0.3 3 9.0 0.4 2.1 1 1 1 2 2 2 0 Protein SOGA Amidohydro_1 PF01979.20 EKX54139.1 - 8.3e-67 225.9 0.0 9.4e-67 225.7 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EKX54139.1 - 8.1e-15 55.2 0.4 3.3e-11 43.3 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family UQ_con PF00179.26 EKX54140.1 - 4.7e-22 78.1 0.0 6e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EKX54140.1 - 0.016 15.5 0.3 0.031 14.6 0.3 1.6 1 1 0 1 1 1 0 RWD domain DUF760 PF05542.11 EKX54141.1 - 6.9e-37 125.7 0.8 2.4e-17 63.1 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF760) DUF2451 PF10474.9 EKX54141.1 - 0.025 14.3 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) LysM PF01476.20 EKX54142.1 - 7.2e-16 58.0 0.0 3.9e-09 36.4 0.1 3.0 2 0 0 2 2 2 2 LysM domain BUD22 PF09073.10 EKX54142.1 - 4.9e-07 29.5 29.7 4.9e-07 29.5 29.7 2.0 2 0 0 2 2 2 1 BUD22 SDA1 PF05285.12 EKX54142.1 - 0.0046 16.4 45.7 0.0046 16.4 45.7 2.1 2 0 0 2 2 2 1 SDA1 LOH1CR12 PF10158.9 EKX54142.1 - 0.19 11.8 1.4 0.45 10.5 1.4 1.6 1 0 0 1 1 1 0 Tumour suppressor protein MORN PF02493.20 EKX54144.1 - 1.7e-41 137.7 47.3 2.8e-07 30.0 1.3 9.0 9 0 0 9 9 9 9 MORN repeat Tudor_2 PF18104.1 EKX54144.1 - 0.011 15.4 0.7 6.4 6.5 0.0 3.6 3 0 0 3 3 3 0 Jumonji domain-containing protein 2A Tudor domain DUF5342 PF17277.2 EKX54144.1 - 0.6 10.5 0.0 0.6 10.5 0.0 3.7 2 1 2 4 4 4 0 Family of unknown function (DUF5342) Ank_2 PF12796.7 EKX54146.1 - 5e-27 94.3 0.0 1.5e-08 35.1 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX54146.1 - 6.2e-26 90.4 0.0 7e-06 26.5 0.0 6.2 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX54146.1 - 2.3e-18 66.0 3.2 0.015 15.6 0.0 6.3 3 3 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX54146.1 - 3.6e-15 54.6 0.1 0.34 11.6 0.0 7.5 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 EKX54146.1 - 8.1e-13 48.2 0.7 0.68 10.5 0.0 7.1 7 0 0 7 7 7 4 Ankyrin repeat Ins_beta PF03488.14 EKX54146.1 - 0.0081 16.1 8.7 2.1 8.4 0.5 4.7 5 0 0 5 5 5 1 Nematode insulin-related peptide beta type VHS PF00790.19 EKX54146.1 - 0.24 11.3 0.6 20 5.0 0.0 3.2 3 1 0 3 3 3 0 VHS domain C1_1 PF00130.22 EKX54146.1 - 8.8 6.3 9.1 0.69 9.8 0.8 3.0 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PDEase_I PF00233.19 EKX54147.1 - 6.2e-77 258.5 2.4 7.7e-77 258.2 2.4 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Imm68 PF15583.6 EKX54147.1 - 0.01 16.0 0.4 0.018 15.3 0.4 1.5 1 1 0 1 1 1 0 Immunity protein 68 HD PF01966.22 EKX54147.1 - 0.054 13.7 0.1 0.13 12.5 0.1 1.7 2 0 0 2 2 2 0 HD domain SPARC_Ca_bdg PF10591.9 EKX54147.1 - 0.092 13.1 1.7 13 6.1 0.0 2.7 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region PDZ_6 PF17820.1 EKX54149.1 - 0.0041 16.9 0.1 0.011 15.6 0.1 1.7 1 0 0 1 1 1 1 PDZ domain DUF1759 PF03564.15 EKX54149.1 - 0.12 12.3 3.6 0.1 12.5 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) TniQ PF06527.11 EKX54149.1 - 3.1 8.5 5.5 0.76 10.5 0.6 2.4 2 1 0 2 2 2 0 TniQ TIG PF01833.24 EKX54150.1 - 1.5e-14 53.8 0.9 1e-10 41.6 0.1 2.4 2 0 0 2 2 2 2 IPT/TIG domain Nrap_D3 PF17404.2 EKX54150.1 - 0.034 14.2 0.1 0.087 12.9 0.1 1.7 1 0 0 1 1 1 0 Nrap protein domain 3 TEA PF01285.18 EKX54150.1 - 0.081 13.0 0.4 0.34 11.0 0.4 2.1 1 0 0 1 1 1 0 TEA/ATTS domain Herpes_UL6 PF01763.16 EKX54150.1 - 0.11 11.0 0.3 0.18 10.3 0.3 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like Spc42p PF11544.8 EKX54150.1 - 0.15 12.1 2.4 0.38 10.8 2.4 1.7 1 0 0 1 1 1 0 Spindle pole body component Spc42p PDZ_2 PF13180.6 EKX54151.1 - 1.7e-06 28.2 0.1 3.9e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX54151.1 - 3.5e-06 27.3 0.1 6.4e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX54151.1 - 7.1e-05 22.6 0.1 0.00014 21.7 0.1 1.5 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX54151.1 - 0.012 15.6 0.1 0.027 14.4 0.1 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain EF-hand_7 PF13499.6 EKX54151.1 - 0.55 10.7 6.4 1.1 9.8 2.5 3.2 2 1 1 3 3 3 0 EF-hand domain pair EGF_MSP1_1 PF12946.7 EKX54153.1 - 0.21 11.7 19.0 0.57 10.3 0.1 4.6 4 0 0 4 4 4 0 MSP1 EGF domain 1 CobU PF02283.16 EKX54154.1 - 4.1e-52 176.2 0.1 5.8e-52 175.7 0.1 1.2 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase DUF4346 PF14251.6 EKX54154.1 - 1.5e-38 131.5 0.0 3.5e-38 130.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4346) ATPase PF06745.13 EKX54154.1 - 0.0066 15.8 0.0 0.016 14.5 0.0 1.6 1 1 0 1 1 1 1 KaiC CPT PF07931.12 EKX54154.1 - 0.13 12.1 0.0 0.36 10.7 0.0 2.0 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.6 EKX54154.1 - 0.19 12.1 0.0 0.38 11.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain PDZ_6 PF17820.1 EKX54155.1 - 5.9e-05 22.8 0.4 0.00016 21.5 0.4 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX54155.1 - 0.0012 19.2 0.0 0.0026 18.1 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX54155.1 - 0.0023 18.2 0.0 0.005 17.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Glycos_transf_1 PF00534.20 EKX54155.1 - 0.025 14.1 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 WD40 PF00400.32 EKX54156.1 - 4.8e-09 36.7 18.3 0.36 11.8 0.2 6.4 6 1 0 6 6 6 5 WD domain, G-beta repeat SCAB-Ig PF16709.5 EKX54157.1 - 0.0035 17.4 0.0 0.0091 16.0 0.0 1.7 1 0 0 1 1 1 1 Ig domain of plant-specific actin-binding protein LRR_4 PF12799.7 EKX54157.1 - 0.011 16.2 0.0 0.2 12.2 0.0 2.4 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) ADH_zinc_N_2 PF13602.6 EKX54158.1 - 1.5e-17 64.8 0.1 1.1e-16 62.1 0.1 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EKX54158.1 - 4.1e-14 52.7 0.5 9.3e-14 51.5 0.3 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EKX54158.1 - 3.9e-07 29.8 0.0 7.3e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N PF08240.12 EKX54158.1 - 1.3e-05 25.0 2.3 0.00013 21.8 0.0 3.1 2 2 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain KR PF08659.10 EKX54158.1 - 0.0026 17.7 0.2 0.0045 16.9 0.2 1.3 1 0 0 1 1 1 1 KR domain AlaDh_PNT_C PF01262.21 EKX54158.1 - 0.014 14.7 0.1 0.021 14.1 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DapB_N PF01113.20 EKX54158.1 - 0.024 14.8 0.1 0.041 14.0 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Castor_Poll_mid PF06241.12 EKX54159.1 - 5.2e-12 45.6 0.0 9.9e-07 28.7 0.0 2.7 2 0 0 2 2 2 2 Castor and Pollux, part of voltage-gated ion channel Glyco_transf_41 PF13844.6 EKX54160.1 - 1.3e-37 129.4 3.5 4e-14 51.9 0.0 4.6 2 2 1 3 3 3 3 Glycosyl transferase family 41 TPR_12 PF13424.6 EKX54160.1 - 0.00021 21.5 1.8 0.00053 20.2 1.8 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX54160.1 - 0.00027 20.8 1.0 0.0083 16.2 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX54160.1 - 0.0052 16.6 0.5 0.0052 16.6 0.5 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX54160.1 - 0.086 12.7 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat P66_CC PF16563.5 EKX54160.1 - 8.6 6.1 10.3 14 5.4 4.7 2.5 2 0 0 2 2 2 0 Coiled-coil and interaction region of P66A and P66B with MBD2 Lung_7-TM_R PF06814.13 EKX54161.1 - 1.4e-16 60.7 23.7 1.9e-16 60.2 23.7 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 EKX54161.1 - 2.6e-16 59.8 5.9 2.6e-16 59.8 5.9 2.6 2 1 1 3 3 3 1 Rhodopsin-like GPCR transmembrane domain Mon1 PF03164.14 EKX54162.1 - 1.1e-22 80.7 0.0 4.3e-22 78.7 0.0 1.7 1 1 0 1 1 1 1 Trafficking protein Mon1 CDC45 PF02724.14 EKX54162.1 - 0.72 8.1 3.0 0.78 8.0 3.0 1.0 1 0 0 1 1 1 0 CDC45-like protein MM_CoA_mutase PF01642.22 EKX54163.1 - 3.8e-222 738.4 0.0 5.3e-222 737.9 0.0 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 EKX54163.1 - 4.3e-14 52.6 0.7 1e-13 51.4 0.7 1.7 1 0 0 1 1 1 1 B12 binding domain Sulfotransfer_1 PF00685.27 EKX54164.1 - 4.6e-29 101.7 0.1 7.2e-29 101.1 0.1 1.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EKX54164.1 - 3.7e-08 34.0 0.0 2.7e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 Sulfotransferase family RINGv PF12906.7 EKX54165.1 - 4.9e-12 45.8 5.2 9.9e-12 44.8 5.2 1.5 1 0 0 1 1 1 1 RING-variant domain ubiquitin PF00240.23 EKX54165.1 - 4.2e-05 23.2 0.0 7.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family PHD PF00628.29 EKX54165.1 - 0.013 15.4 5.7 0.027 14.3 5.7 1.6 1 0 0 1 1 1 0 PHD-finger 5TM-5TMR_LYT PF07694.12 EKX54165.1 - 0.074 12.6 1.5 0.12 11.9 0.5 1.7 1 1 1 2 2 2 0 5TMR of 5TMR-LYT Ion_trans PF00520.31 EKX54166.1 - 7.5e-31 107.2 14.0 1e-18 67.5 5.9 2.1 2 0 0 2 2 2 2 Ion transport protein EF-hand_1 PF00036.32 EKX54166.1 - 0.00021 20.6 0.1 0.0022 17.4 0.0 2.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EKX54166.1 - 0.005 16.7 0.0 0.021 14.7 0.0 2.2 1 0 0 1 1 1 1 EF-hand domain PH PF00169.29 EKX54166.1 - 0.0062 17.0 0.0 0.017 15.6 0.0 1.8 1 0 0 1 1 1 1 PH domain EF-hand_5 PF13202.6 EKX54166.1 - 0.028 13.9 0.3 0.39 10.3 0.0 2.7 2 0 0 2 2 2 0 EF hand PH_9 PF15410.6 EKX54166.1 - 0.062 13.7 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain MSP1_C PF07462.11 EKX54167.1 - 0.082 11.6 0.8 0.11 11.2 0.8 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Cys_Met_Meta_PP PF01053.20 EKX54168.1 - 2.1e-78 263.5 0.0 1.5e-58 198.2 0.0 3.0 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EKX54168.1 - 0.18 10.9 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Ribosomal_L20 PF00453.18 EKX54169.1 - 2.3e-28 98.4 0.5 2.3e-28 98.4 0.5 2.0 1 1 1 2 2 2 1 Ribosomal protein L20 UPF0565 PF10561.9 EKX54170.1 - 1.2e-15 57.5 0.0 1.8e-07 30.7 0.0 3.0 1 1 1 2 2 2 2 Uncharacterised protein family UPF0565 PE-PPE PF08237.11 EKX54170.1 - 0.061 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain DAGAT PF03982.13 EKX54171.1 - 3.1e-85 285.7 0.1 3.8e-84 282.1 0.1 1.9 1 1 0 1 1 1 1 Diacylglycerol acyltransferase WD40 PF00400.32 EKX54172.1 - 1.2e-32 111.4 24.3 2.9e-06 27.9 1.6 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX54172.1 - 3.5e-11 43.2 0.3 0.15 12.4 0.0 5.7 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EKX54172.1 - 9.4e-05 21.2 0.5 3.1 6.4 0.0 3.8 1 1 1 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EKX54172.1 - 0.00012 21.1 0.1 8.7 5.2 0.0 4.6 1 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EKX54172.1 - 0.00039 20.4 0.0 1.1 9.1 0.0 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Hira PF07569.11 EKX54172.1 - 0.0031 17.3 0.1 1.2 8.9 0.0 3.3 1 1 2 3 3 3 1 TUP1-like enhancer of split FHA PF00498.26 EKX54175.1 - 6.3e-11 42.5 0.0 1.2e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 FHA domain CdiA_C_tRNase PF18664.1 EKX54175.1 - 0.028 14.6 0.2 0.067 13.4 0.2 1.6 1 0 0 1 1 1 0 CdiA C-terminal tRNase domain Yop-YscD_cpl PF16697.5 EKX54175.1 - 0.048 14.0 0.0 0.11 12.8 0.0 1.6 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain DUF5587 PF17825.1 EKX54176.1 - 0.0047 14.3 1.3 0.0058 14.0 1.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5587) IFT81_CH PF18383.1 EKX54177.1 - 1.5e-22 80.2 0.4 2.7e-22 79.3 0.0 1.6 2 0 0 2 2 2 1 Intraflagellar transport 81 calponin homology domain ABC_tran_CTD PF16326.5 EKX54177.1 - 0.026 14.8 7.7 1.4 9.2 4.3 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain BLOC1_2 PF10046.9 EKX54177.1 - 0.027 14.7 4.5 0.059 13.7 4.5 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4164 PF13747.6 EKX54177.1 - 0.028 14.7 2.2 0.069 13.4 2.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) AAA_23 PF13476.6 EKX54177.1 - 0.097 13.2 7.6 0.12 12.8 7.6 1.3 1 0 0 1 1 1 0 AAA domain MctB PF11382.8 EKX54177.1 - 0.098 12.3 0.7 0.15 11.8 0.7 1.2 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB VWA_N PF08399.11 EKX54177.1 - 0.11 12.9 2.0 1.1 9.8 0.0 2.2 1 1 1 2 2 2 0 VWA N-terminal Com_YlbF PF06133.11 EKX54177.1 - 0.12 12.9 11.5 0.14 12.8 9.3 2.2 2 1 0 2 2 1 0 Control of competence regulator ComK, YlbF/YmcA Tau95 PF09734.9 EKX54177.1 - 0.16 12.7 1.8 0.29 11.9 1.8 1.3 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain FapA PF03961.13 EKX54177.1 - 0.37 9.3 5.3 0.69 8.5 5.3 1.5 1 0 0 1 1 1 0 Flagellar Assembly Protein A Laminin_II PF06009.12 EKX54177.1 - 0.53 10.3 4.7 0.39 10.7 2.9 1.7 2 0 0 2 2 2 0 Laminin Domain II Pox_A_type_inc PF04508.12 EKX54177.1 - 1.1 9.2 4.9 2.4 8.2 1.0 2.6 1 1 1 2 2 2 0 Viral A-type inclusion protein repeat Swi5 PF07061.11 EKX54177.1 - 2.5 8.3 8.0 1.3 9.2 4.1 2.2 1 1 1 2 2 2 0 Swi5 YabA PF06156.13 EKX54177.1 - 3 8.5 9.6 2.6 8.7 7.4 2.0 2 1 0 2 2 2 0 Initiation control protein YabA NUDIX PF00293.28 EKX54178.1 - 1.7e-16 60.4 0.2 2.2e-16 60.1 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain PHD PF00628.29 EKX54179.1 - 2.5e-14 52.9 9.4 2.7e-14 52.8 9.4 1.0 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EKX54179.1 - 0.00067 19.2 1.8 0.00067 19.2 1.8 1.8 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 EKX54179.1 - 0.0016 18.7 9.8 0.0018 18.6 9.8 1.1 1 0 0 1 1 1 1 Ring finger domain Zf_RING PF16744.5 EKX54179.1 - 0.0019 18.3 3.5 0.0019 18.3 3.5 2.0 1 1 1 2 2 2 1 KIAA1045 RING finger zf-RING-like PF08746.11 EKX54179.1 - 0.0027 18.0 5.9 0.0076 16.5 5.9 1.7 1 1 0 1 1 1 1 RING-like domain zf-RING_9 PF13901.6 EKX54179.1 - 0.014 15.4 4.2 0.015 15.3 4.2 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon C1_2 PF03107.16 EKX54179.1 - 0.02 15.2 6.6 0.025 14.9 3.8 1.9 2 0 0 2 2 2 0 C1 domain zf-rbx1 PF12678.7 EKX54179.1 - 0.026 14.8 8.4 0.035 14.4 8.4 1.1 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-PHD-like PF15446.6 EKX54179.1 - 0.057 13.0 3.7 0.069 12.8 3.7 1.3 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-ANAPC11 PF12861.7 EKX54179.1 - 0.071 13.2 6.3 0.082 13.0 6.3 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RanBP PF00641.18 EKX54179.1 - 0.13 11.6 0.8 0.13 11.6 0.8 3.1 4 0 0 4 4 4 0 Zn-finger in Ran binding protein and others Prok-RING_1 PF14446.6 EKX54179.1 - 0.31 11.0 10.6 0.095 12.6 5.5 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-4CXXC_R1 PF10497.9 EKX54179.1 - 1.2 9.4 10.8 4 7.7 10.8 1.7 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 ADK_lid PF05191.14 EKX54179.1 - 1.5 8.9 9.6 1.7 8.7 0.1 3.0 3 0 0 3 3 3 0 Adenylate kinase, active site lid PhnA_Zn_Ribbon PF08274.12 EKX54179.1 - 3.8 7.5 9.7 1.3 9.1 0.4 2.7 3 0 0 3 3 3 0 PhnA Zinc-Ribbon PHD_4 PF16866.5 EKX54179.1 - 6.6 6.9 14.1 37 4.5 14.1 2.1 1 1 0 1 1 1 0 PHD-finger PHD PF00628.29 EKX54180.1 - 3.3e-12 46.1 7.9 6.1e-12 45.2 7.9 1.5 1 0 0 1 1 1 1 PHD-finger zf-ANAPC11 PF12861.7 EKX54180.1 - 0.078 13.0 4.6 0.17 12.0 4.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EKX54180.1 - 0.15 12.4 5.1 0.32 11.3 5.1 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain C1_2 PF03107.16 EKX54180.1 - 0.28 11.5 8.9 1.8 9.0 6.3 2.4 2 0 0 2 2 2 0 C1 domain zf-RING_2 PF13639.6 EKX54180.1 - 0.42 11.0 9.0 0.83 10.0 9.0 1.5 1 0 0 1 1 1 0 Ring finger domain LRR_6 PF13516.6 EKX54181.1 - 2.4e-09 36.5 22.4 0.14 12.2 0.0 8.6 9 0 0 9 9 9 5 Leucine Rich repeat LRR_4 PF12799.7 EKX54181.1 - 1.1e-06 28.9 21.0 0.057 13.9 0.1 6.8 4 2 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX54181.1 - 0.0086 15.8 23.1 8.2 6.3 0.1 8.0 6 1 0 7 7 7 2 Leucine rich repeat LRR_1 PF00560.33 EKX54181.1 - 0.49 11.1 18.6 62 4.7 0.2 8.3 9 0 0 9 9 9 0 Leucine Rich Repeat DUF5040 PF16443.5 EKX54182.1 - 0.032 13.6 0.2 0.057 12.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5040) Aa_trans PF01490.18 EKX54183.1 - 3.9e-10 39.0 18.4 2.9e-08 32.9 1.3 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EKX54183.1 - 3e-05 23.2 0.9 3e-05 23.2 0.9 2.1 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family FOXP-CC PF16159.5 EKX54184.1 - 0.9 10.2 8.1 0.94 10.2 1.1 2.8 2 1 1 3 3 3 0 FOXP coiled-coil domain DUF2769 PF10967.8 EKX54184.1 - 3.8 8.3 10.0 0.27 11.9 3.8 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2769) LysM PF01476.20 EKX54185.1 - 1.9e-12 47.0 0.3 1.8e-06 27.9 0.1 2.3 2 0 0 2 2 2 2 LysM domain DnaJ PF00226.31 EKX54187.1 - 5.3e-13 48.9 0.1 8e-13 48.3 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 EKX54187.1 - 3.1e-07 30.3 0.0 5.7e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DUF1398 PF07166.11 EKX54187.1 - 0.052 13.6 0.1 0.066 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) DUF3785 PF12653.7 EKX54187.1 - 0.11 12.6 0.4 0.15 12.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3785) Pkinase PF00069.25 EKX54189.1 - 4.9e-63 213.0 0.0 6.3e-63 212.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX54189.1 - 3.4e-34 118.3 0.0 4e-34 118.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX54189.1 - 2.7e-08 33.5 0.0 1.6e-06 27.7 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EKX54189.1 - 5.3e-06 25.9 0.0 7.4e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EKX54189.1 - 0.00027 19.8 0.0 0.00028 19.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EKX54189.1 - 0.0018 17.9 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EKX54189.1 - 0.071 13.0 0.0 0.14 12.0 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family cNMP_binding PF00027.29 EKX54190.1 - 8.4e-11 41.8 0.0 1.5e-09 37.8 0.0 2.0 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain NodZ PF05830.11 EKX54191.1 - 0.068 12.0 0.1 0.17 10.7 0.1 1.6 1 1 0 1 1 1 0 Nodulation protein Z (NodZ) UPF0225 PF17775.1 EKX54192.1 - 5.7e-21 75.2 0.0 8.2e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 UPF0225 domain SEC-C PF02810.15 EKX54192.1 - 0.007 16.3 2.8 0.015 15.3 2.8 1.6 1 0 0 1 1 1 1 SEC-C motif YjcB PF15940.5 EKX54193.1 - 0.021 15.0 1.5 0.021 15.0 1.5 1.6 2 1 1 3 3 3 0 Family of unknown function HTH_48 PF17906.1 EKX54193.1 - 0.11 12.6 0.4 0.82 9.8 0.0 2.3 2 1 0 2 2 2 0 HTH domain in Mos1 transposase DUF3311 PF11755.8 EKX54194.1 - 0.88 9.6 5.5 0.32 10.9 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) Glyco_transf_41 PF13844.6 EKX54195.1 - 5.7e-62 209.7 0.0 9.2e-41 139.8 0.0 2.0 2 0 0 2 2 2 2 Glycosyl transferase family 41 RusA PF05866.11 EKX54196.1 - 6.8e-18 65.4 0.0 1.9e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 Endodeoxyribonuclease RusA Thioredoxin PF00085.20 EKX54197.1 - 0.0014 18.6 0.0 0.003 17.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Dynamin_N PF00350.23 EKX54199.1 - 8.8e-10 38.9 0.0 5.3e-08 33.1 0.0 2.4 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EKX54199.1 - 2.7e-05 24.2 0.0 8.8e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase YpsA PF06908.11 EKX54199.1 - 0.0045 17.0 0.0 0.016 15.2 0.0 1.8 2 0 0 2 2 2 1 YspA SLOG family Roc PF08477.13 EKX54199.1 - 0.032 14.5 0.0 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 EKX54199.1 - 0.04 13.2 0.0 1.6 8.0 0.0 2.3 2 0 0 2 2 2 0 AIG1 family RsgA_GTPase PF03193.16 EKX54199.1 - 0.064 13.2 0.0 1.4 8.8 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase FeoB_N PF02421.18 EKX54199.1 - 0.16 11.5 0.2 1.3 8.5 0.0 2.6 4 0 0 4 4 4 0 Ferrous iron transport protein B G-alpha PF00503.20 EKX54199.1 - 0.21 10.7 0.1 5.8 6.0 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit Guanylate_cyc PF00211.20 EKX54200.1 - 7.4e-48 162.6 0.0 8.2e-48 162.4 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain GCH_III PF05165.12 EKX54200.1 - 0.065 12.5 0.0 0.33 10.2 0.0 1.9 1 1 0 1 1 1 0 GTP cyclohydrolase III Pkinase_Tyr PF07714.17 EKX54201.1 - 1.5e-44 152.2 0.0 1.9e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX54201.1 - 2.1e-35 122.4 0.0 2.7e-35 122.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EKX54201.1 - 0.0032 17.4 0.0 0.0055 16.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EKX54201.1 - 0.022 14.3 0.1 0.033 13.8 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 EKX54201.1 - 0.068 12.1 0.1 0.087 11.7 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EKX54201.1 - 0.14 11.5 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Snf7 PF03357.21 EKX54202.1 - 2.5e-28 98.8 23.7 3.7e-28 98.3 23.7 1.2 1 0 0 1 1 1 1 Snf7 SF3b1 PF08920.10 EKX54202.1 - 0.084 13.4 0.3 0.26 11.8 0.3 1.8 1 1 0 1 1 1 0 Splicing factor 3B subunit 1 DUF1974 PF09317.11 EKX54202.1 - 0.25 10.9 7.1 0.35 10.4 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) PMC2NT PF08066.12 EKX54202.1 - 1.8 9.3 5.8 0.52 11.0 1.3 2.4 2 1 1 3 3 3 0 PMC2NT (NUC016) domain Tweety PF04906.13 EKX54202.1 - 2.1 6.9 6.1 2.9 6.5 6.1 1.2 1 0 0 1 1 1 0 Tweety DUF4962 PF16332.5 EKX54202.1 - 4.8 5.6 7.9 2.2 6.7 5.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4962) hDGE_amylase PF14701.6 EKX54202.1 - 6.2 5.8 9.2 9.1 5.2 9.2 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain GLF PF03275.13 EKX54203.1 - 4.6e-71 238.7 3.8 7.9e-71 238.0 3.7 1.4 2 0 0 2 2 2 1 UDP-galactopyranose mutase NAD_binding_8 PF13450.6 EKX54203.1 - 2.4e-16 59.7 0.1 4.3e-16 58.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EKX54203.1 - 0.00021 21.3 0.1 0.00089 19.3 0.0 2.1 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 EKX54203.1 - 0.00059 20.3 0.2 0.0083 16.7 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EKX54203.1 - 0.00062 19.2 0.0 0.0016 17.8 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 EKX54203.1 - 0.0016 17.9 0.1 0.0039 16.6 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EKX54203.1 - 0.0025 17.1 0.0 0.0055 16.0 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EKX54203.1 - 0.0065 15.7 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EKX54203.1 - 0.01 15.5 0.6 0.014 15.0 0.6 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EKX54203.1 - 0.022 13.8 0.3 0.04 13.0 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 EKX54203.1 - 0.04 13.2 0.1 0.065 12.5 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 EKX54203.1 - 0.055 12.5 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain GDI PF00996.18 EKX54203.1 - 0.067 11.7 0.1 0.11 11.0 0.1 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor GMC_oxred_N PF00732.19 EKX54203.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 GMC oxidoreductase HI0933_like PF03486.14 EKX54203.1 - 0.24 10.1 0.1 0.37 9.4 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Rootletin PF15035.6 EKX54204.1 - 0.31 11.0 5.7 0.19 11.8 1.7 2.4 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF4140 PF13600.6 EKX54204.1 - 0.37 11.3 2.3 4.1 7.9 0.1 2.6 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Pox_A_type_inc PF04508.12 EKX54204.1 - 3.2 7.7 6.8 2 8.4 0.9 2.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat MORN PF02493.20 EKX54205.1 - 1.4e-24 84.4 19.3 3.1e-07 29.9 0.3 5.1 5 0 0 5 5 5 5 MORN repeat PEHE PF15275.6 EKX54206.1 - 0.00061 20.4 0.7 0.00061 20.4 0.7 1.6 2 0 0 2 2 2 1 PEHE domain RB_B PF01857.20 EKX54207.1 - 1.9e-12 47.3 0.1 4.2e-12 46.3 0.1 1.6 1 1 0 1 1 1 1 Retinoblastoma-associated protein B domain Sugar_tr PF00083.24 EKX54208.1 - 3e-31 108.8 11.3 4.9e-31 108.1 11.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter VPS13 PF16908.5 EKX54208.1 - 5.7e-28 98.3 0.1 4.2e-27 95.5 0.0 2.6 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal GRAM PF02893.20 EKX54208.1 - 9.7e-23 80.2 0.2 1.3e-15 57.3 0.1 3.1 3 0 0 3 3 3 2 GRAM domain MFS_1 PF07690.16 EKX54208.1 - 1.5e-16 60.3 33.0 4e-15 55.6 23.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Chorein_N PF12624.7 EKX54208.1 - 3.4e-09 36.8 0.0 1e-08 35.3 0.0 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 EKX54208.1 - 5.4e-06 26.0 0.2 2.7e-05 23.7 0.2 2.2 1 1 0 1 1 1 1 SHR-binding domain of vacuolar-sorting associated protein 13 Sugar_tr PF00083.24 EKX54210.1 - 4.1e-32 111.6 15.9 5.8e-32 111.1 15.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EKX54210.1 - 1.1e-19 70.5 36.0 6.9e-18 64.7 24.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EKX54210.1 - 1.5 7.1 15.5 0.0089 14.5 5.3 2.0 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Enkurin PF13864.6 EKX54211.1 - 9.5e-10 38.8 4.7 9.5e-10 38.8 4.7 2.1 2 0 0 2 2 2 1 Calmodulin-binding Cep57_MT_bd PF06657.13 EKX54211.1 - 0.058 13.9 2.8 0.073 13.5 0.5 2.3 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 AIM5 PF17050.5 EKX54211.1 - 0.083 13.7 1.0 0.083 13.7 1.0 2.2 2 0 0 2 2 2 0 Altered inheritance of mitochondria 5 RINGv PF12906.7 EKX54212.1 - 6.4e-13 48.6 8.7 1.7e-12 47.2 8.7 1.8 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 EKX54212.1 - 0.19 12.1 8.2 0.36 11.2 8.2 1.5 1 0 0 1 1 1 0 Ring finger domain Thioredoxin PF00085.20 EKX54213.1 - 2.9e-28 97.9 0.3 3.2e-28 97.7 0.3 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EKX54213.1 - 6.3e-07 29.5 0.0 8.5e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 EKX54213.1 - 9.4e-06 25.9 0.0 1.3e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EKX54213.1 - 1.6e-05 25.3 0.1 0.00026 21.4 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 EKX54213.1 - 0.00051 19.9 0.0 0.00054 19.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 EKX54213.1 - 0.0019 17.6 0.0 0.002 17.5 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 EKX54213.1 - 0.0056 16.4 0.1 0.022 14.4 0.1 1.7 1 1 1 2 2 2 1 Redoxin Thioredoxin_9 PF14595.6 EKX54213.1 - 0.011 15.5 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_3 PF13192.6 EKX54213.1 - 0.015 15.3 0.1 0.02 14.9 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin domain TraF PF13728.6 EKX54213.1 - 0.022 14.6 0.0 0.025 14.4 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Arabino_trans_C PF14896.6 EKX54213.1 - 0.24 10.4 0.0 0.37 9.7 0.0 1.3 1 0 0 1 1 1 0 EmbC C-terminal domain HAD PF12710.7 EKX54214.1 - 6.5e-25 88.6 0.0 1.9e-24 87.1 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EKX54214.1 - 1.7e-20 74.3 0.3 3.2e-20 73.3 0.3 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ACT_6 PF13740.6 EKX54214.1 - 1.2e-18 66.8 0.1 4.1e-18 65.1 0.1 2.0 2 0 0 2 2 2 1 ACT domain Hydrolase_3 PF08282.12 EKX54214.1 - 1.6e-14 54.3 0.1 4.5e-13 49.5 0.1 2.7 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EKX54214.1 - 9.9e-07 28.4 0.0 0.018 14.5 0.0 2.2 2 0 0 2 2 2 2 Putative Phosphatase HAD_2 PF13419.6 EKX54214.1 - 2.5e-06 27.7 0.1 0.039 14.1 0.0 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase ACT PF01842.25 EKX54214.1 - 0.00016 21.4 0.6 0.017 14.9 0.0 2.7 2 0 0 2 2 2 1 ACT domain PDZ_6 PF17820.1 EKX54215.1 - 1.2e-06 28.3 0.0 4e-06 26.6 0.0 2.0 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX54215.1 - 1.3e-06 28.6 0.2 1.4e-05 25.4 0.0 2.8 2 1 1 3 3 3 1 PDZ domain PDZ_2 PF13180.6 EKX54215.1 - 0.0019 18.5 0.0 0.0074 16.6 0.0 2.1 1 0 0 1 1 1 1 PDZ domain Ins_allergen_rp PF06757.13 EKX54216.1 - 0.023 14.7 0.3 0.1 12.5 0.1 2.0 2 0 0 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification Ins_allergen_rp PF06757.13 EKX54217.1 - 0.023 14.7 0.3 0.1 12.5 0.1 2.0 2 0 0 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification Methyltransf_16 PF10294.9 EKX54218.1 - 1.5e-20 73.7 0.1 2.3e-20 73.1 0.1 1.3 1 1 0 1 1 1 1 Lysine methyltransferase Cons_hypoth95 PF03602.15 EKX54218.1 - 0.0015 18.2 0.0 0.0023 17.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 EKX54218.1 - 0.0068 16.0 0.1 0.013 15.0 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EKX54218.1 - 0.022 15.5 0.0 0.053 14.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EKX54218.1 - 0.027 14.3 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EKX54218.1 - 0.11 12.3 0.1 0.41 10.4 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain SNAPc_SNAP43 PF09808.9 EKX54219.1 - 1e-08 35.3 0.1 6.4e-07 29.5 0.0 2.2 2 0 0 2 2 2 2 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 DUF1741 PF08427.10 EKX54220.1 - 0.00039 20.2 0.0 0.049 13.3 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF1741) DUF4523 PF15023.6 EKX54220.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) RRM_1 PF00076.22 EKX54221.1 - 5.4e-21 74.2 0.0 4.7e-11 42.3 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EKX54221.1 - 0.023 14.8 0.0 1.3 9.1 0.0 2.8 2 0 0 2 2 2 0 RNA binding motif EnY2 PF10163.9 EKX54226.1 - 7.2e-32 109.6 0.5 8.1e-32 109.5 0.5 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 Rep_fac_C PF08542.11 EKX54226.1 - 0.0073 16.7 0.0 0.032 14.6 0.0 1.9 1 1 0 1 1 1 1 Replication factor C C-terminal domain DUF3837 PF12939.7 EKX54226.1 - 0.02 15.3 0.1 0.033 14.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) DUF668 PF05003.12 EKX54226.1 - 0.025 15.0 0.1 3 8.4 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF668) SAP PF02037.27 EKX54226.1 - 1.1 9.2 10.8 1.6 8.6 0.3 3.7 4 0 0 4 4 4 0 SAP domain PA14 PF07691.12 EKX54227.1 - 2.3e-92 306.5 31.3 5.4e-16 58.7 0.0 16.1 18 0 0 18 18 18 12 PA14 domain Filamin PF00630.19 EKX54227.1 - 4.5e-83 274.7 3.1 3.1e-08 34.4 0.0 18.9 18 1 0 18 18 18 15 Filamin/ABP280 repeat GLEYA PF10528.9 EKX54227.1 - 0.0017 18.7 6.5 11 6.6 0.1 8.6 10 0 0 10 10 10 1 GLEYA domain YtkA PF13115.6 EKX54227.1 - 0.056 14.1 0.2 2.7 8.6 0.0 3.3 2 0 0 2 2 2 0 YtkA-like Y_Y_Y PF07495.13 EKX54227.1 - 0.14 12.2 11.5 3.4 7.7 0.1 6.2 6 0 0 6 6 6 0 Y_Y_Y domain Ephrin_rec_like PF07699.13 EKX54228.1 - 1.4e-14 53.5 66.6 0.00072 19.3 1.3 6.8 2 2 5 7 7 7 7 Putative ephrin-receptor like VSP PF03302.13 EKX54228.1 - 0.00028 19.9 40.3 0.034 13.0 15.5 2.1 2 0 0 2 2 2 2 Giardia variant-specific surface protein TNFR_c6 PF00020.18 EKX54228.1 - 0.11 12.9 0.7 0.11 12.9 0.7 7.9 3 3 2 7 7 7 0 TNFR/NGFR cysteine-rich region RTC4 PF14474.6 EKX54228.1 - 0.18 12.0 0.2 0.3 11.2 0.2 1.5 1 0 0 1 1 1 0 RTC4-like domain Laminin_EGF PF00053.24 EKX54228.1 - 1.8 8.8 46.8 0.29 11.3 4.9 7.6 2 2 4 6 6 6 0 Laminin EGF domain SAM_1 PF00536.30 EKX54229.1 - 1.4e-06 28.6 1.5 3e-06 27.6 1.5 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EKX54229.1 - 0.00025 21.1 1.4 0.00046 20.2 0.5 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 EKX54229.1 - 0.072 13.1 1.1 0.18 11.8 1.1 1.6 1 1 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain SAM_Ste50p PF09235.10 EKX54229.1 - 0.094 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Y_phosphatase PF00102.27 EKX54230.1 - 1.7e-06 27.8 0.0 2e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX54230.1 - 2.1e-06 28.0 0.0 2.9e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 EKX54230.1 - 2.2e-06 27.5 0.0 2.8e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EKX54230.1 - 9e-06 25.8 0.0 1.1e-05 25.6 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.12 EKX54230.1 - 0.002 17.8 0.1 0.0033 17.1 0.1 1.4 1 1 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) MoaE PF02391.17 EKX54230.1 - 0.054 13.8 0.0 0.09 13.1 0.0 1.3 1 0 0 1 1 1 0 MoaE protein Y_phosphatase2 PF03162.13 EKX54230.1 - 0.074 12.6 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family TIG PF01833.24 EKX54231.1 - 0.0015 18.5 1.4 0.009 16.1 0.1 2.3 1 1 1 2 2 2 1 IPT/TIG domain TIG PF01833.24 EKX54232.1 - 3.8e-75 248.0 92.1 5.6e-09 35.9 2.1 15.3 15 0 0 15 15 15 14 IPT/TIG domain fn3 PF00041.21 EKX54232.1 - 7.1e-10 39.1 0.2 0.00089 19.6 0.0 3.1 2 0 0 2 2 2 2 Fibronectin type III domain DUF4397 PF14344.6 EKX54232.1 - 0.0008 20.2 0.1 0.017 15.9 0.0 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4397) NnrU PF07298.11 EKX54233.1 - 1.4e-47 162.0 8.5 2e-47 161.4 8.5 1.3 1 0 0 1 1 1 1 NnrU protein PEMT PF04191.13 EKX54233.1 - 0.00022 21.6 0.3 0.00022 21.6 0.3 2.4 3 0 0 3 3 3 1 Phospholipid methyltransferase DUF5362 PF17319.2 EKX54233.1 - 0.086 12.7 1.3 0.19 11.6 0.3 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5362) ICMT PF04140.14 EKX54233.1 - 0.093 13.2 0.5 0.26 11.7 0.2 1.8 1 1 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Tmemb_18A PF09771.9 EKX54233.1 - 0.74 10.2 5.9 7.6 7.0 0.3 2.7 3 0 0 3 3 3 0 Transmembrane protein 188 ECH_2 PF16113.5 EKX54234.1 - 1.5e-89 300.8 0.1 1.7e-89 300.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EKX54234.1 - 1.4e-25 90.0 0.0 2.6e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase tRNA-synt_1c_C PF03950.18 EKX54235.1 - 3.3e-05 23.8 0.0 7.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain BshC PF10079.9 EKX54235.1 - 0.089 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC PPR_2 PF13041.6 EKX54236.1 - 1.1e-08 35.2 6.5 0.066 13.4 0.0 5.8 2 1 4 6 6 6 5 PPR repeat family PPR_3 PF13812.6 EKX54236.1 - 7.5e-07 29.1 0.3 0.0055 16.8 0.0 3.2 2 1 0 3 3 3 1 Pentatricopeptide repeat domain PPR_long PF17177.4 EKX54236.1 - 4.1e-06 26.3 0.0 0.015 14.7 0.0 2.6 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP TPR_MalT PF17874.1 EKX54236.1 - 0.0016 17.9 0.1 0.0062 16.0 0.1 1.8 2 0 0 2 2 2 1 MalT-like TPR region TPR_19 PF14559.6 EKX54236.1 - 0.0043 17.5 0.0 0.26 11.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat DSBA PF01323.20 EKX54236.1 - 0.0063 16.3 0.1 0.036 13.8 0.1 2.4 1 1 0 1 1 1 1 DSBA-like thioredoxin domain CARD_2 PF16739.5 EKX54236.1 - 0.047 13.7 0.5 0.38 10.8 0.1 2.4 2 0 0 2 2 2 0 Caspase recruitment domain Dcc1 PF09724.9 EKX54236.1 - 0.1 11.9 0.2 0.13 11.6 0.2 1.2 1 0 0 1 1 1 0 Sister chromatid cohesion protein Dcc1 PPR PF01535.20 EKX54236.1 - 0.71 10.3 10.4 19 5.8 0.0 5.9 6 1 0 6 6 6 0 PPR repeat PPR_1 PF12854.7 EKX54236.1 - 6.1 6.6 12.4 0.94 9.2 0.2 4.9 4 3 0 4 4 4 0 PPR repeat HEPN_Swt1 PF18731.1 EKX54237.1 - 0.025 14.9 0.3 0.046 14.1 0.3 1.6 1 1 0 1 1 1 0 Swt1-like HEPN ABC_transp_aux PF09822.9 EKX54239.1 - 5.1e-07 29.4 0.0 7.8e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 ABC-type uncharacterized transport system CCB2_CCB4 PF11152.8 EKX54240.1 - 1.1e-26 93.4 1.6 2.5e-16 59.6 0.0 2.1 1 1 1 2 2 2 2 Cofactor assembly of complex C subunit B, CCB2/CCB4 GAF_2 PF13185.6 EKX54240.1 - 0.00011 22.5 0.0 0.00015 22.1 0.0 1.3 1 0 0 1 1 1 1 GAF domain Phage_holin_8 PF16931.5 EKX54240.1 - 0.026 14.5 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative phage holin PH PF00169.29 EKX54241.1 - 9e-12 45.4 0.3 2.3e-11 44.1 0.1 1.8 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 EKX54241.1 - 9.6e-06 25.8 0.2 2.1e-05 24.7 0.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 EKX54241.1 - 0.00093 19.6 2.7 0.0058 17.0 2.7 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 EKX54241.1 - 0.0038 17.3 0.0 0.008 16.3 0.0 1.5 1 0 0 1 1 1 1 PH domain Glyco_transf_7C PF02709.14 EKX54242.1 - 1.6e-19 69.3 0.4 3.1e-19 68.4 0.4 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 EKX54242.1 - 4.9e-11 42.4 0.0 1.4e-10 40.9 0.0 1.8 1 1 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_tranf_2_2 PF10111.9 EKX54242.1 - 0.0077 15.7 0.0 0.32 10.4 0.0 2.3 1 1 1 2 2 2 1 Glycosyltransferase like family 2 Methyltr_RsmB-F PF01189.17 EKX54243.1 - 2e-19 70.0 0.7 5.9e-17 62.0 0.7 3.2 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F UPF0004 PF00919.20 EKX54243.1 - 0.0046 17.0 0.4 0.024 14.7 0.1 2.2 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 Methyltransf_24 PF13578.6 EKX54243.1 - 0.01 16.9 0.0 4.4 8.4 0.1 2.8 2 1 0 2 2 2 0 Methyltransferase domain Orthoreo_P10 PF07204.11 EKX54243.1 - 0.12 12.3 0.2 0.69 9.9 0.0 2.1 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 LRR_4 PF12799.7 EKX54244.1 - 1.2e-08 35.1 11.8 0.00034 20.9 0.4 5.2 4 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX54244.1 - 8.8e-06 25.6 9.1 1.9 9.4 0.9 6.3 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 EKX54244.1 - 4.4e-05 23.2 10.1 3.4 8.0 0.0 6.6 7 1 0 7 7 7 2 Leucine Rich repeat LRR_8 PF13855.6 EKX54244.1 - 0.099 12.4 7.3 15 5.4 0.1 4.9 4 2 1 5 5 5 0 Leucine rich repeat Cnd1_N PF12922.7 EKX54246.1 - 7.1 6.5 15.7 0.16 11.8 2.2 2.1 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term SBF_like PF13593.6 EKX54247.1 - 1.3e-31 110.0 18.6 8e-28 97.7 10.7 2.6 2 1 1 3 3 3 2 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 EKX54247.1 - 2.5e-09 37.1 9.8 2.5e-09 37.1 9.8 1.7 2 0 0 2 2 2 1 Sodium Bile acid symporter family DUF3382 PF11862.8 EKX54247.1 - 0.011 16.0 0.4 0.011 16.0 0.4 2.9 2 2 1 3 3 3 0 Domain of unknown function (DUF3382) TPR_2 PF07719.17 EKX54248.1 - 1.2e-13 50.0 0.6 0.00062 19.7 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat PDZ_6 PF17820.1 EKX54248.1 - 3.6e-13 49.1 0.4 6e-13 48.4 0.4 1.4 1 0 0 1 1 1 1 PDZ domain TPR_1 PF00515.28 EKX54248.1 - 1.5e-11 43.6 0.1 0.024 14.4 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat U-box PF04564.15 EKX54248.1 - 1.8e-11 44.1 0.0 3.3e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 U-box domain PDZ PF00595.24 EKX54248.1 - 1.8e-09 37.8 0.0 3e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX54248.1 - 2e-09 37.7 0.0 3.4e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain TPR_11 PF13414.6 EKX54248.1 - 8.4e-09 35.0 0.0 2.2e-05 24.0 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.6 EKX54248.1 - 7.8e-08 32.5 5.1 0.00073 19.8 1.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX54248.1 - 3.1e-07 30.9 0.1 0.019 15.6 0.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX54248.1 - 1.4e-06 28.0 0.0 0.00029 20.8 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX54248.1 - 1.5e-06 28.3 0.3 0.00025 21.2 0.3 2.7 1 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EKX54248.1 - 4.4e-06 27.1 0.1 0.061 14.2 0.0 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX54248.1 - 1.6e-05 25.0 0.2 0.19 12.2 0.0 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX54248.1 - 0.00054 19.8 0.7 12 6.2 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX54248.1 - 0.0006 20.3 0.0 0.084 13.4 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX54248.1 - 0.00062 20.2 0.2 4.8 8.0 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 EKX54248.1 - 0.001 19.5 3.3 0.059 14.0 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX54248.1 - 0.011 15.9 0.2 0.33 11.1 0.0 2.8 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX54248.1 - 0.014 15.2 2.3 9.2 6.3 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat Tricorn_PDZ PF14685.6 EKX54248.1 - 0.03 14.3 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain PDZ_4 PF17816.1 EKX54248.1 - 0.034 14.6 0.0 2 8.8 0.0 2.4 2 0 0 2 2 2 0 PDZ domain BTAD PF03704.17 EKX54248.1 - 0.067 13.6 1.5 0.6 10.5 1.5 2.3 1 1 0 1 1 1 0 Bacterial transcriptional activator domain DUF3775 PF12616.8 EKX54248.1 - 0.11 12.5 0.2 35 4.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3775) MFS_1 PF07690.16 EKX54249.1 - 7.8e-38 130.3 33.1 3.9e-21 75.4 17.1 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EKX54249.1 - 0.00066 18.6 23.0 0.028 13.3 1.5 3.2 2 1 1 3 3 3 3 MFS_1 like family DUF3592 PF12158.8 EKX54249.1 - 3.1 7.9 6.8 4.6 7.3 0.0 3.3 4 1 0 4 4 4 0 Protein of unknown function (DUF3592) Fer2 PF00111.27 EKX54250.1 - 2.4e-08 33.8 0.7 4e-08 33.1 0.7 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Methyltransf_11 PF08241.12 EKX54252.1 - 7.1e-05 23.4 0.0 0.0029 18.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX54252.1 - 0.011 16.5 0.0 0.04 14.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Cellulase PF00150.18 EKX54254.1 - 2.4e-16 60.0 0.0 3.2e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Guanylate_cyc PF00211.20 EKX54257.1 - 7.6e-29 100.6 0.1 9e-29 100.4 0.1 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Fucose_iso_C PF02952.17 EKX54257.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 L-fucose isomerase, C-terminal domain Guanylate_cyc PF00211.20 EKX54258.1 - 7e-29 100.8 0.1 7.6e-29 100.6 0.1 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.20 EKX54259.1 - 3.3e-22 79.0 0.4 3.6e-22 78.9 0.4 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRIF1 PF15741.5 EKX54260.1 - 8.4 4.8 32.1 13 4.2 32.1 1.4 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 tRNA_bind PF01588.20 EKX54263.1 - 7.1e-07 29.3 0.0 1.6e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain CPSF100_C PF13299.6 EKX54263.1 - 0.16 12.2 7.0 0.29 11.3 7.0 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Spore_coat_CotO PF14153.6 EKX54263.1 - 0.22 11.4 12.1 0.3 11.0 12.1 1.2 1 0 0 1 1 1 0 Spore coat protein CotO RP-C_C PF11800.8 EKX54263.1 - 0.27 11.3 2.3 0.34 11.0 2.3 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region TP53IP5 PF15331.6 EKX54263.1 - 0.64 10.1 7.9 0.92 9.6 7.9 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Zip PF02535.22 EKX54263.1 - 0.69 9.1 3.1 0.77 8.9 3.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 EKX54263.1 - 0.79 8.4 6.1 0.87 8.3 6.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 EKX54263.1 - 1.1 8.0 5.9 1.3 7.7 5.9 1.1 1 0 0 1 1 1 0 Presenilin DDRGK PF09756.9 EKX54263.1 - 1.6 8.3 15.0 2.3 7.8 15.0 1.2 1 0 0 1 1 1 0 DDRGK domain U79_P34 PF03064.16 EKX54263.1 - 2.5 7.4 11.4 3.6 6.9 11.4 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CDC45 PF02724.14 EKX54263.1 - 2.7 6.2 6.8 2.9 6.1 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 EKX54263.1 - 3.7 7.3 13.1 5.4 6.7 13.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Coilin_N PF15862.5 EKX54263.1 - 5.7 6.7 13.4 12 5.7 13.4 1.7 1 0 0 1 1 1 0 Coilin N-terminus MBD PF01429.19 EKX54264.1 - 0.054 13.2 0.0 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 Methyl-CpG binding domain Anoctamin PF04547.12 EKX54265.1 - 3.2e-13 49.3 14.0 9.9e-12 44.4 14.0 2.1 1 1 0 1 1 1 1 Calcium-activated chloride channel TMC PF07810.13 EKX54265.1 - 0.00017 22.1 3.1 0.00017 22.1 3.1 2.7 3 0 0 3 3 3 1 TMC domain TPR_2 PF07719.17 EKX54267.1 - 0.002 18.1 0.5 0.73 10.1 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX54267.1 - 0.014 15.9 0.2 0.046 14.2 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX54267.1 - 0.015 16.0 4.2 0.75 10.8 0.2 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX54267.1 - 0.017 15.4 1.1 0.061 13.6 1.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 EKX54267.1 - 0.024 15.0 0.2 0.22 12.0 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DinI PF06183.13 EKX54267.1 - 0.027 14.8 0.2 0.11 12.9 0.2 2.1 1 0 0 1 1 1 0 DinI-like family TPR_11 PF13414.6 EKX54267.1 - 0.062 13.0 0.0 0.17 11.6 0.0 1.8 1 1 0 1 1 1 0 TPR repeat TPR_10 PF13374.6 EKX54267.1 - 0.38 10.7 2.2 2.6 8.0 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Phycoerythr_ab PF02972.14 EKX54268.1 - 1.2e-16 60.3 0.0 1.9e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Phycoerythrin, alpha/beta chain TAT_signal PF10518.9 EKX54268.1 - 0.047 13.6 0.2 0.047 13.6 0.2 2.8 3 0 0 3 3 3 0 TAT (twin-arginine translocation) pathway signal sequence FimH_man-bind PF09160.10 EKX54268.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 FimH, mannose binding DNA_repr_REX1B PF14966.6 EKX54269.1 - 2.2e-14 53.9 0.4 2.2e-14 53.9 0.4 2.0 2 1 0 2 2 2 1 DNA repair REX1-B DUF16 PF01519.16 EKX54269.1 - 3.5 8.2 8.7 2.8 8.5 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF1043 PF06295.12 EKX54270.1 - 0.01 15.8 0.2 0.01 15.8 0.2 4.7 3 2 1 4 4 4 0 Protein of unknown function (DUF1043) TMEM192 PF14802.6 EKX54270.1 - 0.32 10.0 2.2 0.82 8.7 2.2 1.7 1 0 0 1 1 1 0 TMEM192 family DUF948 PF06103.11 EKX54270.1 - 1.5 9.1 8.5 2.7 8.3 0.1 4.2 2 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF2536 PF10750.9 EKX54270.1 - 1.8 8.5 6.9 2.8 7.9 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2536) BMFP PF04380.13 EKX54270.1 - 2.8 8.5 13.4 6.1 7.4 0.1 4.6 4 0 0 4 4 4 0 Membrane fusogenic activity Whi5 PF08528.11 EKX54271.1 - 0.087 12.5 0.1 0.2 11.3 0.1 1.6 1 0 0 1 1 1 0 Whi5 like Ion_trans PF00520.31 EKX54272.1 - 3.2e-66 223.1 38.9 9.8e-42 142.9 8.6 2.2 2 0 0 2 2 2 2 Ion transport protein GPHH PF16905.5 EKX54272.1 - 0.00034 20.3 0.0 0.00087 19.0 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated CDP-OH_P_transf PF01066.21 EKX54273.1 - 1.7e-17 64.0 0.1 1.7e-17 64.0 0.1 1.5 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase SH3_3 PF08239.11 EKX54274.1 - 6.4e-05 23.2 0.0 0.00014 22.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain ApoC-I PF04691.12 EKX54274.1 - 0.12 12.3 0.0 0.37 10.7 0.0 1.8 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) Pox_A_type_inc PF04508.12 EKX54275.1 - 0.0034 17.2 1.5 0.0034 17.2 1.5 3.9 3 0 0 3 3 3 1 Viral A-type inclusion protein repeat DUF768 PF05589.11 EKX54275.1 - 0.06 13.4 0.3 0.29 11.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF768) DUF3475 PF11961.8 EKX54275.1 - 0.082 13.0 0.3 0.24 11.5 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3475) Gp-FAR-1 PF05823.12 EKX54275.1 - 4.7 7.5 14.6 3.3 8.1 0.8 3.1 2 1 1 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) SlyX PF04102.12 EKX54275.1 - 5.9 7.6 16.0 10 6.8 2.2 3.6 2 1 1 3 3 3 0 SlyX Med2 PF11214.8 EKX54275.1 - 8 6.7 15.1 0.46 10.7 5.9 2.6 1 1 1 2 2 2 0 Mediator complex subunit 2 DUF1041 PF06292.17 EKX54276.1 - 0.11 12.9 0.3 0.14 12.6 0.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1041) PAP_fibrillin PF04755.12 EKX54277.1 - 2.1e-07 31.1 0.0 0.002 18.1 0.0 2.8 3 0 0 3 3 3 2 PAP_fibrillin ECH_2 PF16113.5 EKX54278.1 - 3.2e-59 201.1 0.0 4.1e-58 197.5 0.0 2.3 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EKX54278.1 - 5e-12 45.7 0.0 2.3e-10 40.2 0.0 2.5 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase DUF775 PF05603.12 EKX54278.1 - 0.16 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Myb_DNA-binding PF00249.31 EKX54281.1 - 3.8e-14 52.6 0.2 5.2e-14 52.2 0.2 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX54281.1 - 1.9e-11 44.0 0.5 3e-11 43.4 0.5 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EKX54281.1 - 0.0094 15.8 0.1 0.015 15.2 0.1 1.4 1 1 1 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 EKX54281.1 - 0.025 14.6 0.0 0.028 14.5 0.0 1.1 1 0 0 1 1 1 0 SLIDE SANT_DAMP1_like PF16282.5 EKX54281.1 - 0.068 13.4 0.1 0.075 13.2 0.1 1.2 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 adh_short PF00106.25 EKX54282.1 - 3.5e-49 166.9 1.3 4.5e-49 166.6 1.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EKX54282.1 - 5.1e-45 153.9 0.4 5.9e-45 153.6 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX54282.1 - 5e-10 39.6 4.3 7.5e-09 35.7 4.3 2.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EKX54282.1 - 4.6e-07 29.6 0.0 1e-06 28.4 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EKX54282.1 - 4.1e-05 23.2 0.0 7.5e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EKX54282.1 - 0.00056 19.1 0.0 0.0008 18.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein TrkA_N PF02254.18 EKX54282.1 - 0.0011 19.2 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.19 EKX54282.1 - 0.0012 18.0 0.2 0.002 17.2 0.1 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EKX54282.1 - 0.0014 18.6 0.4 0.0023 17.9 0.1 1.6 2 0 0 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EKX54282.1 - 0.0073 15.4 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Methyltr_RsmB-F PF01189.17 EKX54282.1 - 0.0084 15.8 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Sacchrp_dh_NADP PF03435.18 EKX54282.1 - 0.011 16.0 0.2 0.029 14.6 0.1 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 EKX54282.1 - 0.034 13.8 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EKX54282.1 - 0.082 12.8 0.2 0.16 11.8 0.1 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TRP PF06011.12 EKX54284.1 - 1.3e-07 30.7 2.1 1.3e-07 30.7 2.1 1.5 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel Kelch_1 PF01344.25 EKX54284.1 - 2.4e-07 30.2 0.4 0.0059 16.2 0.0 4.1 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 EKX54284.1 - 7.2e-07 29.3 18.1 7.8e-05 22.8 0.0 8.0 9 1 0 9 9 9 1 Kelch motif Kelch_5 PF13854.6 EKX54284.1 - 1.9e-05 24.6 3.8 0.00052 19.9 0.0 4.1 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.6 EKX54284.1 - 0.00013 21.9 13.5 0.0024 17.9 0.0 5.9 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_3 PF13415.6 EKX54284.1 - 0.0002 21.6 12.3 0.0017 18.6 0.1 5.9 6 0 0 6 6 6 1 Galactose oxidase, central domain Chlam_PMP PF02415.17 EKX54284.1 - 0.13 12.8 6.9 71 4.2 0.1 5.3 4 0 0 4 4 4 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Pkinase PF00069.25 EKX54285.1 - 3.3e-59 200.4 0.0 3.9e-59 200.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX54285.1 - 6.9e-36 123.8 0.0 8.8e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX54285.1 - 9.9e-09 34.9 0.0 3.9e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EKX54285.1 - 4.6e-06 26.1 0.0 6.9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EKX54285.1 - 0.0089 15.6 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EKX54285.1 - 0.012 14.5 0.0 0.02 13.8 0.0 1.3 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EKX54285.1 - 0.017 15.1 0.1 0.095 12.6 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EKX54285.1 - 0.019 14.0 0.6 0.033 13.3 0.1 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 Beta_helix PF13229.6 EKX54286.1 - 3e-57 192.9 54.4 3.8e-22 78.8 8.5 3.7 1 1 2 3 3 3 3 Right handed beta helix region NosD PF05048.13 EKX54286.1 - 1.5e-41 142.3 21.8 1.2e-15 57.5 4.9 3.1 1 1 2 3 3 3 3 Periplasmic copper-binding protein (NosD) Arm PF00514.23 EKX54287.1 - 3.9e-11 42.6 0.9 2.7e-05 24.0 0.0 4.3 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EKX54287.1 - 3.3e-07 30.2 0.5 0.01 15.8 0.1 2.8 2 1 1 3 3 3 2 Spinocerebellar ataxia type 10 protein domain PPR_2 PF13041.6 EKX54288.1 - 0.057 13.6 0.1 13 6.1 0.0 3.0 3 0 0 3 3 3 0 PPR repeat family DUF563 PF04577.14 EKX54289.1 - 0.073 13.2 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF563) Snf7 PF03357.21 EKX54290.1 - 3e-45 153.9 10.4 3.4e-45 153.7 10.4 1.0 1 0 0 1 1 1 1 Snf7 Syntaxin-6_N PF09177.11 EKX54290.1 - 0.001 19.6 0.5 0.14 12.7 0.0 2.3 2 1 0 2 2 2 1 Syntaxin 6, N-terminal DUF1319 PF07028.11 EKX54290.1 - 0.0027 17.9 1.0 0.0047 17.1 0.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1319) Flagellin_C PF00700.21 EKX54290.1 - 0.14 12.5 4.0 0.16 12.3 1.9 2.1 1 1 0 1 1 1 0 Bacterial flagellin C-terminal helical region DUF1664 PF07889.12 EKX54290.1 - 0.78 9.8 7.2 1.1 9.3 1.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CdvA PF18822.1 EKX54290.1 - 1.2 9.0 6.9 1.3 8.9 1.6 2.9 1 1 2 3 3 3 0 CdvA-like coiled-coil domain Prefoldin_2 PF01920.20 EKX54290.1 - 2.1 8.3 8.0 2.8 7.9 0.0 3.0 2 1 1 3 3 3 0 Prefoldin subunit Pilin_PilA PF14245.6 EKX54292.1 - 0.048 13.7 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 Type IV pilin PilA Cep57_CLD_2 PF14197.6 EKX54293.1 - 0.022 14.9 0.3 0.022 14.9 0.3 4.6 4 0 0 4 4 4 0 Centrosome localisation domain of PPC89 GIT_CC PF16559.5 EKX54293.1 - 0.29 11.0 3.0 11 5.9 0.8 3.1 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor APG6_N PF17675.1 EKX54293.1 - 0.36 11.4 20.5 10 6.6 0.0 3.9 2 1 0 2 2 2 0 Apg6 coiled-coil region APC1_C PF18122.1 EKX54294.1 - 0.0048 16.9 0.0 0.01 15.8 0.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain FlgM PF04316.13 EKX54294.1 - 0.0048 17.2 0.2 0.097 13.0 0.1 3.0 2 0 0 2 2 2 1 Anti-sigma-28 factor, FlgM PrmA PF06325.13 EKX54294.1 - 0.024 14.0 0.0 0.051 13.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DOT1 PF08123.13 EKX54294.1 - 0.025 14.1 0.1 0.11 12.0 0.1 1.9 1 1 0 1 1 1 0 Histone methylation protein DOT1 RICTOR_V PF14668.6 EKX54294.1 - 0.058 13.6 0.1 0.99 9.7 0.0 2.5 1 1 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 Methyltransf_31 PF13847.6 EKX54294.1 - 0.075 12.8 0.0 0.36 10.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.6 EKX54294.1 - 0.11 12.4 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain HEAT_2 PF13646.6 EKX54294.1 - 0.14 12.5 1.9 4.3 7.8 0.2 3.1 1 1 1 2 2 2 0 HEAT repeats HEAT_EZ PF13513.6 EKX54294.1 - 0.87 10.2 6.2 3.8 8.1 0.4 3.0 2 1 1 3 3 3 0 HEAT-like repeat 2OG-FeII_Oxy_2 PF13532.6 EKX54295.1 - 1e-16 61.7 0.0 1.9e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FTO_NTD PF12933.7 EKX54295.1 - 0.0072 15.6 0.0 0.12 11.6 0.0 2.1 2 0 0 2 2 2 1 FTO catalytic domain GST_C_3 PF14497.6 EKX54296.1 - 6.1e-05 23.1 0.0 0.00025 21.2 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EKX54296.1 - 0.00015 22.1 0.0 0.00027 21.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF1940 PF09155.10 EKX54296.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) JIP_LZII PF16471.5 EKX54298.1 - 0.024 14.8 3.0 9.9 6.4 2.5 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF1192 PF06698.11 EKX54298.1 - 0.038 14.0 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) TPR_MLP1_2 PF07926.12 EKX54298.1 - 0.12 12.4 9.1 0.24 11.5 9.1 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein HrpB7 PF09486.10 EKX54298.1 - 0.18 12.2 4.5 0.42 11.0 0.2 2.3 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Fib_alpha PF08702.10 EKX54298.1 - 0.3 11.3 4.1 0.68 10.1 4.1 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FapA PF03961.13 EKX54298.1 - 0.53 8.8 7.0 1 7.9 7.0 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A ZapB PF06005.12 EKX54298.1 - 1.5 9.4 13.7 1.1 9.7 10.3 2.2 2 0 0 2 2 2 0 Cell division protein ZapB DUF1664 PF07889.12 EKX54298.1 - 2.5 8.2 5.3 23 5.0 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.15 EKX54298.1 - 3.9 7.3 10.1 3.5 7.5 6.3 2.3 2 0 0 2 2 2 0 Septum formation initiator CCDC-167 PF15188.6 EKX54298.1 - 4.5 7.7 14.2 4 7.8 11.6 2.2 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Radical_SAM PF04055.21 EKX54299.1 - 2.9e-13 50.5 0.0 4.1e-12 46.8 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily LIAS_N PF16881.5 EKX54299.1 - 7.6e-09 36.0 0.1 2.6e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family SAM_2 PF07647.17 EKX54300.1 - 1.7e-15 56.9 0.1 2.3e-14 53.3 0.0 2.8 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EKX54300.1 - 4.6e-14 52.6 0.5 1.7e-13 50.8 0.0 2.3 3 0 0 3 3 2 1 SAM domain (Sterile alpha motif) TPR_12 PF13424.6 EKX54300.1 - 7.4e-12 45.4 0.0 0.22 11.8 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 EKX54300.1 - 0.00023 21.0 0.3 4.5 7.6 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat SAM_3 PF18016.1 EKX54300.1 - 0.00024 20.8 0.5 0.044 13.6 0.1 2.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) TPR_1 PF00515.28 EKX54300.1 - 0.0032 17.2 0.3 1.3 8.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX54300.1 - 0.023 14.9 1.5 1.2 9.5 0.5 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX54300.1 - 0.033 14.1 0.3 2.7 8.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat SAM_PNT PF02198.16 EKX54300.1 - 0.041 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain ApbE PF02424.15 EKX54300.1 - 0.042 13.4 0.2 1.1 8.7 0.1 2.3 1 1 1 2 2 2 0 ApbE family SKA2 PF16740.5 EKX54300.1 - 0.77 9.6 5.2 1.5 8.6 3.0 2.5 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 BT1 PF03092.16 EKX54301.1 - 7.9e-88 295.0 21.7 3e-50 170.9 5.8 2.8 2 1 1 3 3 3 2 BT1 family MFS_1 PF07690.16 EKX54301.1 - 2e-18 66.5 38.0 2e-18 66.5 38.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EKX54301.1 - 0.00015 20.8 22.0 0.00023 20.2 22.0 1.4 1 0 0 1 1 1 1 MFS_1 like family TMEM126 PF07114.11 EKX54301.1 - 0.041 13.3 0.9 0.092 12.1 0.1 2.0 2 0 0 2 2 2 0 Transmembrane protein 126 WSD PF15613.6 EKX54302.1 - 2.2e-13 50.5 0.0 2.2e-13 50.5 0.0 3.5 3 1 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif FYRN PF05964.14 EKX54302.1 - 2.4e-06 27.3 0.0 5.6e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 EKX54302.1 - 2.1e-05 24.6 0.2 0.0051 16.9 0.2 2.8 1 1 0 1 1 1 1 F/Y rich C-terminus Mito_carr PF00153.27 EKX54304.1 - 4.7e-32 109.8 0.0 1.5e-15 56.9 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein E1-E2_ATPase PF00122.20 EKX54306.1 - 9.3e-28 97.0 0.6 9.3e-28 97.0 0.6 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EKX54306.1 - 2.2e-10 41.2 0.0 0.041 14.1 0.0 3.2 2 1 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EKX54306.1 - 4.5e-07 29.5 0.0 1.5e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EKX54306.1 - 0.00065 19.7 0.0 0.0017 18.4 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) DUF445 PF04286.12 EKX54308.1 - 0.022 14.6 17.9 0.03 14.1 17.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF3040 PF11239.8 EKX54308.1 - 0.32 11.3 2.2 0.77 10.1 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) PARP PF00644.20 EKX54309.1 - 2.6e-09 36.9 0.1 4.9e-09 36.1 0.1 1.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain ARTD15_N PF18084.1 EKX54309.1 - 3.3e-07 30.5 0.0 6.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 ARTD15 N-terminal domain SAP PF02037.27 EKX54310.1 - 0.00062 19.5 4.8 0.00085 19.0 0.4 3.2 3 0 0 3 3 3 1 SAP domain EF-hand_6 PF13405.6 EKX54311.1 - 0.021 14.7 0.0 0.084 12.9 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 EKX54311.1 - 0.06 12.9 0.0 0.3 10.7 0.0 2.2 2 0 0 2 2 2 0 EF hand PFU PF09070.11 EKX54311.1 - 0.064 13.5 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) EF-hand_7 PF13499.6 EKX54311.1 - 0.098 13.1 0.0 0.46 11.0 0.0 2.2 1 0 0 1 1 1 0 EF-hand domain pair Hom_end PF05204.14 EKX54311.1 - 0.3 11.3 2.4 10 6.3 0.3 2.5 2 0 0 2 2 2 0 Homing endonuclease KapB PF08810.10 EKX54311.1 - 1.6 8.9 6.9 2.5 8.3 2.2 2.8 2 0 0 2 2 2 0 Kinase associated protein B AHH PF14412.6 EKX54311.1 - 1.7 8.8 5.3 0.4 10.8 0.4 2.5 2 1 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH cNMP_binding PF00027.29 EKX54312.1 - 7.9e-09 35.5 0.2 2.4e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain EMC3_TMCO1 PF01956.16 EKX54312.1 - 9.9 5.9 6.2 26 4.5 6.2 1.7 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Peptidase_S9 PF00326.21 EKX54313.1 - 2e-12 47.0 0.0 3.5e-12 46.2 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EKX54313.1 - 9.4e-07 28.9 0.0 1.3e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EKX54313.1 - 4.7e-06 27.4 1.1 0.0011 19.6 0.9 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EKX54313.1 - 0.00061 19.1 0.0 0.017 14.4 0.0 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EKX54313.1 - 0.00085 19.0 0.0 0.0027 17.4 0.0 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 EKX54313.1 - 0.024 13.6 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme BAAT_C PF08840.11 EKX54313.1 - 0.045 13.7 0.0 1.4 8.8 0.0 2.1 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Ser_hydrolase PF06821.13 EKX54313.1 - 0.065 13.1 0.0 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase YjbR PF04237.13 EKX54313.1 - 0.14 12.7 0.0 0.24 12.0 0.0 1.5 1 1 0 1 1 1 0 YjbR O-FucT PF10250.9 EKX54315.1 - 2.1e-07 31.0 0.1 1.9e-06 27.8 0.1 2.2 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase NodZ PF05830.11 EKX54315.1 - 3.6e-06 26.0 0.0 6e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein Z (NodZ) EGF_2 PF07974.13 EKX54315.1 - 0.0002 21.6 9.2 0.00052 20.3 9.2 1.8 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.27 EKX54315.1 - 0.69 10.3 10.0 0.083 13.2 4.8 2.3 2 0 0 2 2 2 0 EGF-like domain MSC PF09402.10 EKX54315.1 - 7.4 5.9 6.5 0.62 9.5 1.6 1.6 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain TPR_19 PF14559.6 EKX54316.1 - 3.6e-15 56.2 2.5 0.00016 22.1 0.2 4.9 5 1 0 5 5 4 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX54316.1 - 1.9e-11 44.0 25.2 4.9e-05 23.5 1.5 5.5 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EKX54316.1 - 6.1e-11 41.6 18.8 0.8 10.0 0.0 9.4 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_12 PF13424.6 EKX54316.1 - 1.5e-06 28.3 9.2 0.029 14.7 0.1 6.0 5 2 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX54316.1 - 1.9e-05 25.0 7.1 0.13 12.9 0.1 6.1 8 0 0 8 8 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX54316.1 - 0.0002 21.9 0.2 43 5.3 0.0 5.8 6 1 1 7 7 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 EKX54316.1 - 0.00026 21.1 0.2 0.028 14.6 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX54316.1 - 0.001 19.0 4.5 1.6 8.9 0.9 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EKX54316.1 - 0.0011 19.0 15.2 0.19 11.8 0.0 4.6 3 1 1 4 4 4 2 Putative TPR-like repeat HrpB1_HrpK PF09613.10 EKX54316.1 - 0.0023 17.6 0.1 0.28 10.8 0.0 3.7 4 1 1 5 5 5 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_16 PF13432.6 EKX54316.1 - 0.0025 18.4 0.1 55 4.5 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX54316.1 - 0.52 10.3 3.6 10 6.2 0.3 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Coatomer_E PF04733.14 EKX54316.1 - 0.95 8.8 5.2 4.2 6.7 0.1 3.6 3 1 1 5 5 5 0 Coatomer epsilon subunit TPR_1 PF00515.28 EKX54316.1 - 2.3 8.2 25.6 25 4.9 0.1 7.8 9 0 0 9 9 9 0 Tetratricopeptide repeat Bcr-Abl_Oligo PF09036.10 EKX54317.1 - 0.018 15.0 2.1 0.067 13.2 0.3 2.9 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain tRNA_int_endo PF01974.17 EKX54318.1 - 0.00017 21.6 0.1 0.00029 20.8 0.1 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain ABC_tran PF00005.27 EKX54319.1 - 1.3e-29 103.4 0.3 4.4e-19 69.4 0.0 3.1 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 EKX54319.1 - 2.7e-07 30.7 3.1 0.0055 16.5 0.1 3.3 2 1 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 EKX54319.1 - 3.2e-05 23.9 4.2 4.7e-05 23.3 4.2 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EKX54319.1 - 0.00056 19.4 0.3 5.9 6.3 0.0 3.2 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 EKX54319.1 - 0.0062 16.6 0.7 0.05 13.7 0.0 2.1 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 EKX54319.1 - 0.01 16.1 0.0 0.038 14.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EKX54319.1 - 0.022 15.0 0.1 0.092 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EKX54319.1 - 0.027 15.0 0.6 0.2 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EKX54319.1 - 0.039 13.9 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase SURF6 PF04935.12 EKX54319.1 - 0.039 13.7 0.7 0.061 13.1 0.7 1.2 1 0 0 1 1 1 0 Surfeit locus protein 6 DUF3975 PF13126.6 EKX54319.1 - 0.042 14.3 0.1 0.08 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3975) AAA PF00004.29 EKX54319.1 - 0.047 14.1 0.0 0.52 10.7 0.0 2.5 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EKX54319.1 - 0.055 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain NuDC PF16273.5 EKX54319.1 - 0.066 13.8 0.8 0.12 12.9 0.8 1.3 1 0 0 1 1 1 0 Nuclear distribution C domain AAA_16 PF13191.6 EKX54319.1 - 0.081 13.3 0.4 0.82 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 EKX54319.1 - 0.14 11.9 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP-synt_ab PF00006.25 EKX54319.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 EKX54319.1 - 0.19 12.1 0.0 0.46 10.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF3584 PF12128.8 EKX54319.1 - 1.2 6.5 5.1 0.93 6.9 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) LRR_6 PF13516.6 EKX54320.1 - 1.3e-06 28.0 6.3 0.19 11.8 0.0 5.1 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 EKX54320.1 - 5.4e-05 23.5 12.8 0.0013 19.1 0.2 3.9 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX54320.1 - 0.011 15.4 11.7 0.016 14.9 0.4 3.5 3 1 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 EKX54320.1 - 0.059 13.9 5.5 92 4.2 0.1 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat DUF1126 PF06565.12 EKX54321.1 - 9.1e-91 298.7 1.8 5.9e-35 119.3 0.1 3.6 3 1 0 3 3 3 3 DUF1126 PH-like domain TIR_2 PF13676.6 EKX54322.1 - 2.1e-05 25.1 0.0 7.1e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 TIR domain DUF1863 PF08937.11 EKX54322.1 - 0.086 13.2 0.4 0.19 12.1 0.0 1.7 2 0 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) CAP_N PF01213.19 EKX54324.1 - 2e-78 264.1 0.0 3.1e-78 263.4 0.0 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 EKX54324.1 - 2.3e-51 173.5 5.4 3.2e-51 173.0 5.4 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 EKX54324.1 - 0.041 13.6 9.1 0.38 10.5 9.4 2.1 1 1 0 1 1 1 0 Tubulin binding cofactor C DDRGK PF09756.9 EKX54325.1 - 9.1e-35 120.0 0.1 1.1e-34 119.7 0.1 1.1 1 0 0 1 1 1 1 DDRGK domain FeoC PF09012.10 EKX54325.1 - 0.00017 21.6 0.1 0.002 18.2 0.0 2.0 2 0 0 2 2 2 1 FeoC like transcriptional regulator DUF2418 PF10332.9 EKX54326.1 - 0.001 19.5 0.4 0.001 19.5 0.4 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2418) Pro_isomerase PF00160.21 EKX54327.1 - 1.6e-45 155.2 0.0 1.8e-45 155.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DDE_1 PF03184.19 EKX54328.1 - 4.5e-21 75.3 0.0 9.8e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EKX54328.1 - 5.5e-10 39.1 0.3 1.8e-09 37.5 0.1 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_28 PF13518.6 EKX54328.1 - 2.2e-05 24.5 0.0 0.0012 19.0 0.1 2.9 3 0 0 3 3 3 1 Helix-turn-helix domain CENP-B_N PF04218.13 EKX54328.1 - 0.00045 19.8 0.2 0.00088 18.9 0.2 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_23 PF13384.6 EKX54328.1 - 0.003 17.3 0.9 0.011 15.5 0.1 2.4 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4 PF04545.16 EKX54328.1 - 0.0062 16.0 0.3 0.018 14.5 0.3 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.6 EKX54328.1 - 0.018 14.8 0.5 0.037 13.8 0.5 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain BrkDBD PF09607.10 EKX54328.1 - 0.019 14.7 0.0 0.054 13.3 0.0 1.7 1 0 0 1 1 1 0 Brinker DNA-binding domain HTH_35 PF13693.6 EKX54328.1 - 0.03 14.4 1.6 0.16 12.0 0.1 2.7 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_Tnp_ISL3 PF13542.6 EKX54328.1 - 0.072 12.5 0.0 0.21 11.1 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_psq PF05225.16 EKX54328.1 - 0.14 12.0 0.1 0.45 10.3 0.1 2.0 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Trp_repressor PF01371.19 EKX54328.1 - 0.17 12.0 0.2 0.42 10.8 0.2 1.7 1 0 0 1 1 1 0 Trp repressor protein Gly_transf_sug PF04488.15 EKX54329.1 - 2.5e-09 37.6 0.0 7e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 EKX54329.1 - 0.001 18.4 1.2 0.019 14.3 0.7 2.1 1 1 1 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.12 EKX54329.1 - 0.004 16.6 0.0 0.0066 15.9 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gb3_synth PF04572.12 EKX54329.1 - 0.02 15.1 0.3 1.4 9.1 0.3 2.3 1 1 0 1 1 1 0 Alpha 1,4-glycosyltransferase conserved region Glyco_transf_10 PF00852.19 EKX54332.1 - 1.7e-11 44.2 0.0 3.4e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Ion_trans PF00520.31 EKX54333.1 - 1e-40 139.5 10.4 1.3e-40 139.2 10.4 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX54333.1 - 2.4e-14 53.0 2.2 2.4e-14 53.0 2.2 3.1 3 0 0 3 3 3 1 Ion channel PKD_channel PF08016.12 EKX54333.1 - 3.2 6.3 7.9 0.17 10.5 1.8 1.8 2 0 0 2 2 2 0 Polycystin cation channel Phageshock_PspD PF09584.10 EKX54334.1 - 0.073 13.1 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 Phage shock protein PspD (Phageshock_PspD) LRR_6 PF13516.6 EKX54335.1 - 2.8e-33 111.1 25.2 0.00028 20.7 0.0 12.2 12 0 0 12 12 12 8 Leucine Rich repeat LRR_4 PF12799.7 EKX54335.1 - 5.8e-05 23.4 27.2 0.069 13.6 0.4 8.0 6 4 3 9 9 9 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX54335.1 - 0.00025 20.8 33.5 0.034 13.9 3.3 8.9 6 3 3 9 9 9 3 Leucine rich repeat LRR_1 PF00560.33 EKX54335.1 - 0.13 12.9 34.0 26 5.9 0.2 11.7 11 3 0 11 11 11 0 Leucine Rich Repeat FA_desaturase PF00487.24 EKX54336.1 - 2.6e-17 63.5 14.1 3.4e-17 63.1 14.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase PgaD PF13994.6 EKX54336.1 - 0.06 13.4 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 PgaD-like protein Fe-S_assembly PF04384.13 EKX54338.1 - 0.15 12.7 0.1 0.44 11.2 0.1 1.8 1 0 0 1 1 1 0 Iron-sulphur cluster assembly DUF2012 PF09430.10 EKX54339.1 - 2.1e-21 76.3 0.0 3e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) SOP4 PF17081.5 EKX54339.1 - 0.0012 18.4 0.1 0.0023 17.5 0.1 1.4 1 0 0 1 1 1 1 Suppressor of PMA 1-7 protein CarbopepD_reg_2 PF13715.6 EKX54339.1 - 0.0056 16.6 0.0 0.013 15.5 0.0 1.6 2 0 0 2 2 2 1 CarboxypepD_reg-like domain Pkinase PF00069.25 EKX54340.1 - 3.2e-59 200.4 0.0 4.6e-59 199.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX54340.1 - 2e-35 122.3 0.1 5.3e-35 120.9 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EKX54340.1 - 7.9e-14 51.8 0.1 1.5e-13 50.9 0.1 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 EKX54340.1 - 7e-05 22.3 0.0 0.0014 18.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EKX54340.1 - 0.00052 18.9 0.0 0.00083 18.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX54340.1 - 0.1 12.5 0.0 0.74 9.7 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family HGTP_anticodon PF03129.20 EKX54341.1 - 2.1e-16 59.9 0.1 2.2e-15 56.6 0.0 2.5 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EKX54341.1 - 6.7e-12 45.7 0.0 1.3e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.20 EKX54341.1 - 0.0035 17.5 2.2 0.0035 17.5 2.2 2.3 2 0 0 2 2 2 1 WHEP-TRS domain Coa1 PF08695.10 EKX54342.1 - 0.0011 18.7 0.1 0.0018 18.0 0.1 1.4 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 IBB PF01749.20 EKX54342.1 - 0.047 14.1 1.8 0.091 13.2 1.8 1.4 1 0 0 1 1 1 0 Importin beta binding domain Geminin PF07412.12 EKX54342.1 - 0.057 13.2 0.5 0.12 12.1 0.5 1.4 1 0 0 1 1 1 0 Geminin MRC1 PF09444.10 EKX54342.1 - 0.24 11.9 3.2 0.29 11.6 0.7 2.2 2 0 0 2 2 2 0 MRC1-like domain PKcGMP_CC PF16808.5 EKX54342.1 - 2.1 8.3 7.9 0.35 10.7 2.3 2.4 2 1 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CoaE PF01121.20 EKX54343.1 - 6.1e-46 156.3 0.0 6.9e-46 156.2 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.6 EKX54343.1 - 0.0013 18.9 0.0 0.0018 18.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EKX54343.1 - 0.044 14.0 0.0 0.069 13.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EKX54343.1 - 0.066 13.8 0.1 0.12 12.9 0.1 1.4 1 1 0 1 1 1 0 AAA domain ESCRT-II PF05871.12 EKX54343.1 - 0.2 11.9 0.0 0.25 11.6 0.0 1.2 1 0 0 1 1 1 0 ESCRT-II complex subunit PAS_9 PF13426.7 EKX54344.1 - 3.4e-05 24.0 0.0 7.5e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 PAS domain PAS PF00989.25 EKX54344.1 - 0.063 13.3 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 PAS fold MMR_HSR1_Xtn PF16897.5 EKX54345.1 - 8e-40 135.1 0.2 1.4e-39 134.4 0.2 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EKX54345.1 - 8.7e-20 70.9 0.0 1.6e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 EKX54345.1 - 9.9e-18 63.9 0.0 2.7e-17 62.6 0.0 1.7 2 0 0 2 2 2 1 TGS domain FeoB_N PF02421.18 EKX54345.1 - 3.3e-10 39.7 0.0 7.1e-10 38.6 0.0 1.5 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EKX54345.1 - 0.0025 17.9 0.2 0.12 12.4 0.0 2.3 1 1 1 2 2 2 1 Dynamin family LON_substr_bdg PF02190.16 EKX54346.1 - 2.5e-05 24.2 0.0 7.2e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain EF-hand_1 PF00036.32 EKX54347.1 - 5.4e-09 35.0 1.0 0.0034 16.8 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EKX54347.1 - 9.4e-08 31.2 1.8 0.0041 16.5 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX54347.1 - 5e-06 26.0 0.1 0.089 12.8 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EKX54347.1 - 9.9e-06 25.9 0.3 2.8e-05 24.5 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 EKX54347.1 - 2.7e-05 23.9 0.3 0.0017 18.1 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair Peptidase_M16 PF00675.20 EKX54348.1 - 2.4e-48 163.9 0.3 3.5e-48 163.3 0.3 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EKX54348.1 - 5e-27 95.1 0.0 1.1e-25 90.8 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain Pkinase PF00069.25 EKX54349.1 - 8.3e-64 215.5 0.4 9.9e-64 215.2 0.4 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX54349.1 - 1.1e-16 60.9 0.0 1.7e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX54349.1 - 1.3e-06 28.5 0.0 9.7e-06 25.7 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX54349.1 - 0.0068 15.2 0.0 0.016 14.0 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EKX54349.1 - 0.032 13.6 0.1 0.056 12.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EKX54349.1 - 0.038 13.6 0.1 0.068 12.7 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RWP-RK PF02042.15 EKX54350.1 - 7.2e-16 57.9 0.0 1.3e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain PKD_channel PF08016.12 EKX54352.1 - 1.9e-14 53.2 2.4 7.7e-14 51.2 2.4 1.9 1 1 0 1 1 1 1 Polycystin cation channel EF-hand_1 PF00036.32 EKX54352.1 - 0.00057 19.3 0.3 0.0013 18.2 0.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EKX54352.1 - 0.005 16.7 0.1 0.015 15.2 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 EKX54352.1 - 0.0084 15.6 0.8 0.02 14.4 0.8 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EKX54352.1 - 0.024 15.1 0.1 0.061 13.8 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair DUF2177 PF09945.9 EKX54352.1 - 0.046 13.8 0.3 0.09 12.9 0.3 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2177) Bac_rhodopsin PF01036.18 EKX54354.1 - 2.5e-45 154.8 18.9 3.3e-45 154.4 18.9 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Bac_rhodopsin PF01036.18 EKX54355.1 - 3.3e-37 128.2 20.0 4e-37 128.0 20.0 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Nucleos_tra2_C PF07662.13 EKX54355.1 - 0.18 11.6 11.0 0.07 13.0 4.4 2.2 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter C-terminus DUF4131 PF13567.6 EKX54355.1 - 3.1 7.4 12.0 3.1 7.4 3.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4191 PF13829.6 EKX54355.1 - 3.5 6.9 10.8 0.28 10.5 3.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Aa_trans PF01490.18 EKX54356.1 - 1.9e-09 36.7 10.4 4.2e-07 29.0 1.5 2.7 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein GHMP_kinases_C PF08544.13 EKX54356.1 - 0.12 12.8 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 GHMP kinases C terminal DUF5079 PF16882.5 EKX54356.1 - 0.21 11.4 0.0 0.21 11.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5079) HSP90 PF00183.18 EKX54357.1 - 5.8e-238 791.0 27.9 7.6e-238 790.6 27.9 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EKX54357.1 - 3.1e-15 56.6 0.2 2.8e-14 53.6 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EKX54357.1 - 3.7e-09 36.5 0.2 1e-08 35.1 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2052 PF09747.9 EKX54357.1 - 1.1 9.3 13.7 0.18 11.9 8.2 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Peptidase_S8 PF00082.22 EKX54358.1 - 4.7e-26 91.7 1.6 5.7e-26 91.5 1.6 1.0 1 0 0 1 1 1 1 Subtilase family Lipase_GDSL_2 PF13472.6 EKX54358.1 - 0.0083 16.5 0.1 0.011 16.1 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DEAD PF00270.29 EKX54359.1 - 3.7e-40 137.5 0.0 2e-39 135.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX54359.1 - 8.3e-27 93.7 0.0 2.2e-26 92.4 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX54359.1 - 0.0041 17.1 0.0 0.01 15.8 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EKX54359.1 - 0.0069 16.7 0.1 0.088 13.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain Ig_mannosidase PF17753.1 EKX54360.1 - 0.032 14.0 0.0 0.079 12.7 0.0 1.6 1 0 0 1 1 1 0 Ig-fold domain NAD_binding_5 PF07994.12 EKX54361.1 - 2.8e-144 480.4 0.0 3.3e-144 480.2 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EKX54361.1 - 1.9e-47 160.0 0.4 4e-47 159.0 0.4 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase YppG PF14179.6 EKX54362.1 - 0.0059 17.3 0.0 0.025 15.3 0.0 2.0 2 0 0 2 2 2 1 YppG-like protein WD40 PF00400.32 EKX54363.1 - 8.2e-25 86.6 17.0 0.00013 22.7 0.2 9.8 9 0 0 9 9 9 6 WD domain, G-beta repeat EF-hand_1 PF00036.32 EKX54363.1 - 1.2e-09 37.0 4.2 0.00021 20.6 0.2 3.0 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 EKX54363.1 - 1.7e-09 36.8 0.3 0.00056 19.3 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX54363.1 - 3.8e-09 36.3 0.2 1.3e-05 25.0 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX54363.1 - 1.2e-08 34.2 0.5 0.014 15.3 0.0 3.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EKX54363.1 - 1.3e-06 28.8 0.0 5.1e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 EF-hand domain pair ANAPC4_WD40 PF12894.7 EKX54363.1 - 2e-05 24.8 2.9 1.2 9.5 0.0 5.3 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EKX54363.1 - 7.3e-05 21.7 4.3 0.5 9.1 0.7 4.4 2 2 2 4 4 4 2 Nup133 N terminal like EF-hand_4 PF12763.7 EKX54363.1 - 0.044 13.7 1.4 5.2 7.1 0.0 3.3 3 0 0 3 3 3 0 Cytoskeletal-regulatory complex EF hand ECH_1 PF00378.20 EKX54364.1 - 1e-51 175.7 1.6 1.2e-51 175.5 1.6 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EKX54364.1 - 1.3e-28 100.5 1.5 4.7e-28 98.7 0.9 1.8 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 EKX54364.1 - 0.043 13.8 0.2 3.1 7.7 0.0 2.4 1 1 1 2 2 2 0 Peptidase family S49 Thioredoxin_6 PF13848.6 EKX54365.1 - 6.4e-05 22.9 0.1 6.4e-05 22.9 0.1 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain TMEM223 PF14640.6 EKX54365.1 - 0.12 12.6 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 223 BCDHK_Adom3 PF10436.9 EKX54366.1 - 9.1e-41 139.4 0.0 1.3e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EKX54366.1 - 1.4e-10 41.7 0.0 2.4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EKX54366.1 - 0.003 17.4 0.0 0.0053 16.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ank_5 PF13857.6 EKX54367.1 - 8.8e-14 51.4 0.1 7.2e-12 45.3 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX54367.1 - 3.5e-13 49.8 0.0 7e-09 36.0 0.0 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EKX54367.1 - 1.4e-11 44.2 2.8 7.6e-07 29.3 0.0 3.5 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EKX54367.1 - 4.1e-11 43.3 0.1 5.5e-11 42.9 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX54367.1 - 1.7e-10 40.2 0.2 1.5e-05 25.0 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Mod_r PF07200.13 EKX54368.1 - 0.019 15.1 2.7 0.019 15.1 2.7 2.0 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF3489 PF11994.8 EKX54368.1 - 0.025 14.6 0.1 0.084 12.9 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3489) Chrome_Resist PF09828.9 EKX54368.1 - 0.032 14.7 0.5 3.5 8.1 0.2 2.1 2 0 0 2 2 2 0 Chromate resistance exported protein DUF2262 PF10020.9 EKX54368.1 - 0.068 13.6 4.4 0.14 12.5 4.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) HrpB7 PF09486.10 EKX54368.1 - 0.18 12.2 5.1 1.4 9.3 5.1 2.0 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF4618 PF15397.6 EKX54368.1 - 0.42 10.0 10.6 0.38 10.1 3.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) EF-G-binding_N PF07299.11 EKX54368.1 - 0.69 10.5 4.3 0.57 10.7 0.6 2.5 3 0 0 3 3 3 0 Elongation factor G-binding protein, N-terminal Hrs_helical PF12210.8 EKX54368.1 - 0.84 10.2 8.1 0.41 11.2 5.1 1.9 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Ax_dynein_light PF10211.9 EKX54368.1 - 0.86 9.5 10.2 3.5 7.5 5.2 2.2 2 0 0 2 2 2 0 Axonemal dynein light chain DUF16 PF01519.16 EKX54368.1 - 0.94 10.0 7.2 6.5 7.3 2.9 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 MAGE_N PF12440.8 EKX54368.1 - 1.3 9.8 7.1 0.5 11.1 4.2 1.7 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal DUF1043 PF06295.12 EKX54368.1 - 2.7 8.0 7.4 2.6 8.1 4.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) Collagen PF01391.18 EKX54368.1 - 7.6 6.4 12.1 0.11 12.2 4.4 1.8 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Fib_alpha PF08702.10 EKX54368.1 - 7.7 6.7 8.8 7.5 6.7 3.5 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family E2F_TDP PF02319.20 EKX54369.1 - 1.8e-19 69.6 0.1 5e-19 68.1 0.1 1.8 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain DP PF08781.10 EKX54369.1 - 5.7e-19 68.4 2.4 1.3e-18 67.2 2.4 1.7 1 0 0 1 1 1 1 Transcription factor DP CDC37_N PF03234.14 EKX54369.1 - 0.53 11.2 6.4 0.71 10.8 1.7 2.4 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding DAO PF01266.24 EKX54370.1 - 2.6e-41 142.4 0.3 3.4e-41 142.0 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EKX54370.1 - 8.8e-09 34.9 0.2 8.8e-09 34.9 0.2 1.8 2 1 0 2 2 1 1 FAD binding domain NAD_binding_8 PF13450.6 EKX54370.1 - 5.8e-08 32.8 0.3 3e-07 30.6 0.3 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EKX54370.1 - 3.5e-07 29.7 0.1 4.9e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EKX54370.1 - 8.3e-07 29.5 1.5 2.5e-05 24.7 1.4 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EKX54370.1 - 4.4e-05 22.9 0.1 7.1e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EKX54370.1 - 5.2e-05 22.6 1.2 9.9e-05 21.7 1.2 1.4 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 EKX54370.1 - 6.1e-05 23.0 0.1 0.00011 22.1 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 EKX54370.1 - 6.5e-05 22.3 0.8 0.00022 20.5 0.4 1.9 2 0 0 2 2 2 1 Thi4 family ApbA PF02558.16 EKX54370.1 - 0.00025 20.7 0.4 0.0015 18.2 0.1 2.3 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EKX54370.1 - 0.0013 19.0 0.0 0.0025 18.1 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.6 EKX54370.1 - 0.0015 19.0 0.0 0.003 18.0 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_9 PF13454.6 EKX54370.1 - 0.0023 17.9 0.1 0.032 14.2 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EKX54370.1 - 0.0028 16.4 1.3 0.01 14.6 1.8 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 EKX54370.1 - 0.0071 15.6 0.6 0.013 14.8 0.6 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EKX54370.1 - 0.0076 15.3 0.1 0.013 14.6 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 EKX54370.1 - 0.011 15.1 3.6 0.019 14.3 1.1 2.4 2 1 0 2 2 2 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 EKX54370.1 - 0.015 14.9 0.9 0.19 11.3 0.5 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Amino_oxidase PF01593.24 EKX54370.1 - 0.021 14.1 0.4 0.13 11.6 0.2 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase ThiF PF00899.21 EKX54370.1 - 0.04 13.3 0.1 0.084 12.2 0.1 1.5 1 0 0 1 1 1 0 ThiF family XdhC_C PF13478.6 EKX54370.1 - 0.12 12.9 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain NAD_Gly3P_dh_N PF01210.23 EKX54370.1 - 0.13 12.2 1.4 0.29 11.1 0.3 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 EKX54370.1 - 0.16 12.2 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EKX54370.1 - 0.19 11.8 0.3 0.36 10.9 0.3 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 EKX54370.1 - 0.23 10.5 2.0 0.46 9.5 2.0 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF1188 PF06690.11 EKX54370.1 - 0.25 10.8 0.1 0.42 10.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) Glyco_transf_92 PF01697.27 EKX54372.1 - 7.8e-26 91.3 0.2 9.2e-26 91.0 0.2 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 EKX54372.1 - 3e-18 66.1 0.2 3.7e-18 65.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glycos_transf_2 PF00535.26 EKX54372.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 1 0 1 1 1 0 Glycosyl transferase family 2 DUF1604 PF07713.13 EKX54373.1 - 7.8e-36 121.8 5.3 1.9e-34 117.3 4.1 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.23 EKX54373.1 - 1.8e-05 24.5 0.6 1.8e-05 24.5 0.6 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 EKX54373.1 - 0.00012 22.1 0.2 0.0013 18.8 0.2 2.9 1 1 0 1 1 1 1 G-patch domain zf-CCCH PF00642.24 EKX54375.1 - 1.8e-13 50.0 16.7 2.1e-05 24.3 0.1 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EKX54375.1 - 1.9e-11 43.6 27.8 0.0009 19.2 5.8 3.4 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH_3 PF15663.5 EKX54375.1 - 3.1e-06 27.4 10.6 0.00017 21.8 4.4 2.9 1 1 2 3 3 3 3 Zinc-finger containing family zf-CCCH_4 PF18044.1 EKX54375.1 - 5.2e-06 26.1 20.8 0.00048 19.8 0.3 3.5 3 0 0 3 3 3 3 CCCH-type zinc finger Torus PF16131.5 EKX54375.1 - 8.6e-06 26.4 16.7 0.0062 17.2 3.0 3.8 1 1 2 3 3 3 2 Torus domain zf-CCCH_2 PF14608.6 EKX54375.1 - 0.11 13.0 28.1 0.71 10.4 5.6 3.9 3 1 0 3 3 3 0 RNA-binding, Nab2-type zinc finger Ephrin_rec_like PF07699.13 EKX54376.1 - 2.8e-51 171.1 91.5 1.8e-10 40.4 7.2 9.2 5 2 4 9 9 9 9 Putative ephrin-receptor like NCD3G PF07562.14 EKX54376.1 - 1.9e-09 37.4 75.0 0.0057 16.6 0.8 9.2 7 2 2 9 9 9 7 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 EKX54376.1 - 0.0013 19.0 67.4 0.23 11.9 1.0 11.2 6 5 4 10 10 10 8 TNFR/NGFR cysteine-rich region SHIPPO-rpt PF07004.12 EKX54376.1 - 0.86 10.6 4.2 12 7.0 0.2 3.6 3 0 0 3 3 3 0 Sperm-tail PG-rich repeat EF-hand_7 PF13499.6 EKX54377.1 - 3.2e-12 46.7 0.6 6.2e-09 36.2 0.4 3.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX54377.1 - 1e-11 43.5 2.3 0.0066 15.9 0.0 3.9 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EKX54377.1 - 1.3e-09 37.2 0.3 0.055 13.4 0.0 3.9 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 EKX54377.1 - 1.3e-07 30.8 3.5 0.006 16.0 0.1 3.8 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EKX54377.1 - 0.054 13.3 1.7 1.1 9.1 0.1 3.5 2 1 1 3 3 3 0 EF-hand domain pair Spt5_N PF11942.8 EKX54377.1 - 1.3 10.0 6.7 3.9 8.5 2.6 2.9 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal PRP1_N PF06424.12 EKX54378.1 - 7e-41 140.1 1.8 7e-41 140.1 1.8 2.2 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 EKX54378.1 - 2.6e-22 77.6 29.4 0.028 15.2 0.1 13.1 8 2 6 14 14 13 6 Tetratricopeptide repeat TPR_19 PF14559.6 EKX54378.1 - 3.3e-18 65.9 13.7 0.00058 20.3 0.0 8.4 7 1 3 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.6 EKX54378.1 - 1.8e-09 37.1 0.1 0.1 12.3 0.0 6.4 6 1 0 6 6 6 2 TPR repeat TPR_2 PF07719.17 EKX54378.1 - 1.7e-08 34.0 13.7 0.15 12.2 0.0 8.5 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX54378.1 - 3e-06 27.8 11.2 0.08 13.6 0.1 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX54378.1 - 4.4e-06 26.5 1.1 0.96 9.8 0.0 6.3 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX54378.1 - 1.2e-05 24.9 2.1 0.74 9.7 0.0 6.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX54378.1 - 4.2e-05 23.6 2.3 37 5.0 0.0 7.3 7 2 0 8 8 8 0 Tetratricopeptide repeat Suf PF05843.14 EKX54378.1 - 0.00011 22.4 0.2 0.021 14.8 0.0 4.0 5 0 0 5 5 5 1 Suppressor of forked protein (Suf) TPR_6 PF13174.6 EKX54378.1 - 0.00022 21.6 8.9 0.24 12.1 0.0 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX54378.1 - 0.0015 18.8 4.1 9.2 6.6 0.1 5.6 5 1 1 6 6 5 1 Tetratricopeptide repeat ZNRF_3_ecto PF18212.1 EKX54378.1 - 0.0028 17.6 0.1 0.53 10.3 0.0 3.4 3 0 0 3 3 3 1 ZNRF-3 Ectodomain TPR_7 PF13176.6 EKX54378.1 - 0.081 13.0 0.3 8.6 6.7 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX54378.1 - 0.26 11.5 4.8 47 4.3 0.0 4.6 5 1 0 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 FAT PF02259.23 EKX54378.1 - 0.27 10.4 18.7 0.14 11.3 0.5 4.6 3 2 0 4 4 4 0 FAT domain Flg_hook PF02120.16 EKX54379.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK Metallophos PF00149.28 EKX54380.1 - 1.3e-24 87.9 0.2 1.5e-24 87.6 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase LRR_6 PF13516.6 EKX54381.1 - 2.3e-24 83.3 15.6 0.00032 20.5 0.2 8.2 8 0 0 8 8 8 6 Leucine Rich repeat LRR_4 PF12799.7 EKX54381.1 - 2e-10 40.7 8.8 0.01 16.2 0.0 5.3 2 1 4 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX54381.1 - 1e-05 25.2 15.8 1.4 8.7 0.0 6.6 4 3 0 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 EKX54381.1 - 0.0003 20.9 8.0 4 8.4 0.9 6.4 5 1 0 5 5 5 1 Leucine Rich Repeat LRR_9 PF14580.6 EKX54381.1 - 0.21 11.1 0.1 12 5.4 0.0 2.2 1 1 1 2 2 2 0 Leucine-rich repeat DUF2891 PF11199.8 EKX54382.1 - 2.2e-48 164.9 7.6 4.7e-24 84.9 1.3 4.1 1 1 2 3 3 3 3 Protein of unknown function (DUF2891) HSP90 PF00183.18 EKX54384.1 - 1.4e-238 793.0 30.5 1.8e-238 792.6 30.5 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EKX54384.1 - 1.7e-15 57.5 0.3 2.8e-14 53.6 0.1 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EKX54384.1 - 3.4e-09 36.6 0.2 1e-08 35.1 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ATP-sulfurylase PF01747.17 EKX54385.1 - 1.6e-67 227.1 0.0 2.3e-67 226.6 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 EKX54385.1 - 4.8e-37 127.1 0.0 7.2e-37 126.5 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain SbcD_C PF12320.8 EKX54386.1 - 0.043 14.1 0.1 0.066 13.5 0.1 1.2 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain DUF3198 PF11433.8 EKX54386.1 - 0.25 11.3 0.2 0.25 11.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) Cluap1 PF10234.9 EKX54387.1 - 0.028 13.8 0.7 0.028 13.8 0.7 2.4 2 0 0 2 2 2 0 Clusterin-associated protein-1 VSG_B PF13206.6 EKX54387.1 - 0.029 13.6 8.3 0.75 9.0 1.1 2.6 2 1 1 3 3 3 0 Trypanosomal VSG domain NuiA PF07924.11 EKX54387.1 - 0.087 13.2 1.6 0.58 10.6 0.0 2.7 3 0 0 3 3 3 0 Nuclease A inhibitor-like protein DUF503 PF04456.12 EKX54387.1 - 0.19 11.6 3.4 1.9 8.4 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF503) SurA_N_3 PF13624.6 EKX54388.1 - 0.0067 16.2 0.0 0.044 13.6 0.1 2.1 2 1 0 2 2 2 1 SurA N-terminal domain SurA_N_2 PF13623.6 EKX54388.1 - 0.014 15.2 0.1 0.022 14.6 0.1 1.3 1 0 0 1 1 1 0 SurA N-terminal domain Patatin PF01734.22 EKX54389.1 - 9.4e-18 65.1 2.3 5.8e-17 62.5 2.3 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase C2 PF00168.30 EKX54389.1 - 3.9e-12 46.4 0.0 7.2e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain zf_CCCH_5 PF18384.1 EKX54390.1 - 0.073 13.2 1.0 0.2 11.8 1.0 1.7 1 0 0 1 1 1 0 Unkempt Zinc finger domain 1 (Znf1) TMCO5 PF14992.6 EKX54390.1 - 0.39 10.2 3.0 0.95 9.0 1.3 2.0 2 0 0 2 2 2 0 TMCO5 family Malic_M PF03949.15 EKX54392.1 - 4.6e-97 324.3 0.1 5.8e-97 324.0 0.1 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EKX54392.1 - 7.9e-76 253.9 0.0 2.6e-74 249.0 0.0 2.1 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain CobU PF02283.16 EKX54392.1 - 0.088 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase RNA_pol_Rpb1_2 PF00623.20 EKX54393.1 - 2.3e-61 206.8 0.0 4.4e-61 205.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_5 PF04998.17 EKX54393.1 - 1.9e-51 175.0 2.7 1.2e-48 165.8 0.6 2.9 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 EKX54393.1 - 3.7e-33 115.2 11.1 1.1e-31 110.4 11.1 2.5 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 EKX54393.1 - 4.1e-26 91.8 0.0 9.9e-26 90.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EKX54393.1 - 5e-21 74.7 0.0 5e-21 74.7 0.0 3.2 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 SDA1 PF05285.12 EKX54393.1 - 7.4e-05 22.3 14.8 7.4e-05 22.3 14.8 2.3 2 0 0 2 2 2 1 SDA1 DUF2457 PF10446.9 EKX54393.1 - 8.3e-05 21.9 20.3 8.3e-05 21.9 20.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) Sporozoite_P67 PF05642.11 EKX54393.1 - 0.00087 17.5 15.0 0.00087 17.5 15.0 2.5 2 1 1 3 3 2 1 Sporozoite P67 surface antigen BUD22 PF09073.10 EKX54393.1 - 0.0042 16.5 54.1 0.017 14.5 21.6 2.2 2 0 0 2 2 2 2 BUD22 Nop14 PF04147.12 EKX54393.1 - 1.2 7.2 61.0 0.0088 14.3 22.5 2.2 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.14 EKX54393.1 - 7.3 4.7 46.1 0.32 9.3 16.9 2.2 2 0 0 2 2 2 0 CDC45-like protein Dpy-30 PF05186.13 EKX54394.1 - 1.3e-14 53.6 0.3 1.6e-14 53.3 0.3 1.1 1 0 0 1 1 1 1 Dpy-30 motif ADK PF00406.22 EKX54395.1 - 4.3e-117 387.2 0.0 9e-47 159.0 0.0 3.9 4 0 0 4 4 4 3 Adenylate kinase AAA_17 PF13207.6 EKX54395.1 - 1.9e-65 219.4 0.0 5.2e-27 94.9 0.0 3.5 3 0 0 3 3 3 3 AAA domain AAA_18 PF13238.6 EKX54395.1 - 4.2e-17 62.9 0.0 1.2e-06 29.1 0.0 3.9 3 1 0 3 3 3 3 AAA domain Hydin_ADK PF17213.3 EKX54395.1 - 1.1e-12 48.7 8.7 0.11 12.8 0.0 6.2 3 3 3 6 6 6 4 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 EKX54395.1 - 1.7e-11 44.5 0.0 0.0013 18.9 0.0 4.5 3 3 0 3 3 3 3 AAA domain Zeta_toxin PF06414.12 EKX54395.1 - 5.7e-08 32.3 1.3 0.026 13.8 0.2 3.5 3 0 0 3 3 3 2 Zeta toxin Thymidylate_kin PF02223.17 EKX54395.1 - 1.4e-07 31.4 0.2 6.5 6.4 0.0 6.2 6 1 0 6 6 6 1 Thymidylate kinase Cytidylate_kin PF02224.18 EKX54395.1 - 1.7e-07 31.2 0.1 0.055 13.2 0.0 3.3 3 0 0 3 3 3 2 Cytidylate kinase AAA PF00004.29 EKX54395.1 - 5.9e-05 23.5 0.1 3.6 8.0 0.0 3.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ADK_lid PF05191.14 EKX54395.1 - 7.3e-05 22.7 3.2 0.12 12.4 0.1 3.5 3 0 0 3 3 3 1 Adenylate kinase, active site lid KTI12 PF08433.10 EKX54395.1 - 0.00057 19.4 0.2 0.37 10.2 0.0 3.2 3 0 0 3 3 3 1 Chromatin associated protein KTI12 AAA_24 PF13479.6 EKX54395.1 - 0.00085 19.1 0.2 5.3 6.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 EKX54395.1 - 0.0016 18.2 0.2 8.3 6.1 0.0 3.2 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EKX54395.1 - 0.0066 16.9 1.5 19 5.6 0.0 3.5 3 0 0 3 3 3 0 AAA ATPase domain FIST_C PF10442.9 EKX54395.1 - 0.0071 16.3 0.0 0.026 14.5 0.0 1.9 1 0 0 1 1 1 1 FIST C domain AAA_28 PF13521.6 EKX54395.1 - 0.011 15.9 0.2 2 8.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 EKX54395.1 - 0.017 15.4 0.3 35 4.6 0.0 3.5 3 0 0 3 3 3 0 AAA domain Guanylate_kin PF00625.21 EKX54395.1 - 0.018 14.7 0.2 72 3.0 0.0 4.6 6 0 0 6 6 6 0 Guanylate kinase Mg_chelatase PF01078.21 EKX54395.1 - 0.089 12.2 0.5 4.2 6.7 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI DIM1 PF02966.16 EKX54395.1 - 0.12 12.1 0.3 34 4.2 0.0 3.3 4 0 0 4 4 4 0 Mitosis protein DIM1 T2SSE PF00437.20 EKX54395.1 - 0.18 10.8 0.3 18 4.3 0.0 2.9 3 0 0 3 3 3 0 Type II/IV secretion system protein ADK PF00406.22 EKX54396.1 - 3.4e-48 163.6 0.0 4e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EKX54396.1 - 2.5e-28 99.2 0.0 4.2e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EKX54396.1 - 5.1e-08 33.5 0.0 8.9e-08 32.7 0.0 1.3 1 1 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 EKX54396.1 - 8.1e-05 23.0 0.5 0.043 14.1 0.0 2.3 1 1 1 2 2 2 2 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 EKX54396.1 - 0.0035 17.5 0.0 0.013 15.7 0.0 2.1 1 1 1 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 EKX54396.1 - 0.0071 16.1 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase Thymidylate_kin PF02223.17 EKX54396.1 - 0.009 15.7 0.1 3 7.5 0.0 2.4 3 0 0 3 3 3 2 Thymidylate kinase ADK_lid PF05191.14 EKX54396.1 - 0.01 15.8 0.1 0.027 14.5 0.1 1.7 1 1 0 1 1 1 0 Adenylate kinase, active site lid Zeta_toxin PF06414.12 EKX54396.1 - 0.044 13.1 0.1 0.076 12.3 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin GST_N_2 PF13409.6 EKX54397.1 - 5.9e-13 48.9 0.0 1.1e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EKX54397.1 - 1.4e-09 37.8 0.0 3e-09 36.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EKX54397.1 - 6.3e-06 26.3 0.0 9.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EKX54397.1 - 7e-05 22.9 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EKX54397.1 - 0.00012 22.4 0.0 0.0027 18.1 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Use1 PF09753.9 EKX54399.1 - 0.0078 16.0 0.1 0.0089 15.8 0.1 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 T6PP_N PF18572.1 EKX54399.1 - 0.061 13.2 0.1 0.079 12.8 0.1 1.2 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Complex1_LYR PF05347.15 EKX54400.1 - 8.5e-07 28.9 0.1 1.1e-06 28.6 0.1 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EKX54400.1 - 0.0078 16.9 0.2 0.0087 16.8 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like HAUS2 PF15003.6 EKX54400.1 - 0.021 14.6 0.4 0.023 14.5 0.4 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 HEAT_2 PF13646.6 EKX54401.1 - 0.0069 16.8 0.1 0.044 14.2 0.1 2.5 1 0 0 1 1 1 1 HEAT repeats RICTOR_M PF14666.6 EKX54401.1 - 0.007 16.1 0.7 3.7 7.4 0.1 2.9 2 0 0 2 2 2 2 Rapamycin-insensitive companion of mTOR, middle domain RTP1_C1 PF10363.9 EKX54401.1 - 0.062 13.5 0.9 0.97 9.6 0.1 2.9 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 EKX54401.1 - 0.15 12.4 0.2 2.7 8.5 0.1 3.2 3 0 0 3 3 3 0 HEAT repeat L27_N PF09060.10 EKX54401.1 - 0.2 11.8 2.3 24 5.1 0.9 3.6 3 0 0 3 3 3 0 L27_N Pkinase PF00069.25 EKX54402.1 - 4.9e-18 65.4 0.0 6.9e-18 65.0 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX54402.1 - 0.029 13.7 0.8 0.062 12.6 0.0 1.9 3 0 0 3 3 3 0 Protein tyrosine kinase RWP-RK PF02042.15 EKX54404.1 - 2e-13 50.1 0.0 3e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_31 PF13560.6 EKX54404.1 - 0.043 14.2 0.1 0.075 13.4 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain PspB PF06667.12 EKX54405.1 - 0.16 12.0 0.0 0.61 10.2 0.0 2.0 1 0 0 1 1 1 0 Phage shock protein B GAS PF13851.6 EKX54406.1 - 0.00027 20.4 8.7 0.00027 20.4 8.7 2.0 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding DivIC PF04977.15 EKX54406.1 - 0.0016 18.1 2.5 0.0016 18.1 2.5 2.6 2 1 1 3 3 2 1 Septum formation initiator JAKMIP_CC3 PF16034.5 EKX54406.1 - 0.0049 16.8 7.1 0.0049 16.8 7.1 1.7 2 0 0 2 2 1 1 JAKMIP CC3 domain FapA PF03961.13 EKX54406.1 - 0.0061 15.2 3.0 0.012 14.3 3.0 1.6 1 0 0 1 1 1 1 Flagellar Assembly Protein A FlaC_arch PF05377.11 EKX54406.1 - 0.0063 16.9 3.5 0.37 11.2 0.4 2.6 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.8 EKX54406.1 - 0.0075 16.5 7.9 0.026 14.7 7.9 1.9 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding EzrA PF06160.12 EKX54406.1 - 0.011 14.0 5.3 0.017 13.3 5.3 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA CCDC144C PF14915.6 EKX54406.1 - 0.012 14.8 6.6 0.012 14.8 6.6 2.1 2 1 0 2 2 2 0 CCDC144C protein coiled-coil region ERM PF00769.19 EKX54406.1 - 0.013 15.4 5.3 0.013 15.4 5.3 1.7 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF3450 PF11932.8 EKX54406.1 - 0.013 14.8 2.9 0.021 14.1 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) BAR_3 PF16746.5 EKX54406.1 - 0.018 14.7 6.9 0.023 14.4 6.2 1.5 1 1 0 1 1 1 0 BAR domain of APPL family DUF2813 PF11398.8 EKX54406.1 - 0.023 14.0 3.1 0.032 13.5 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) AAA_11 PF13086.6 EKX54406.1 - 0.027 14.3 1.2 0.038 13.8 1.2 1.2 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.8 EKX54406.1 - 0.029 11.9 5.7 0.04 11.5 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4618 PF15397.6 EKX54406.1 - 0.03 13.8 7.5 0.13 11.6 6.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) BLOC1_2 PF10046.9 EKX54406.1 - 0.033 14.5 2.6 0.033 14.5 2.6 2.5 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 STAT_alpha PF01017.20 EKX54406.1 - 0.034 14.0 5.9 0.069 13.0 5.9 1.5 1 0 0 1 1 1 0 STAT protein, all-alpha domain JIP_LZII PF16471.5 EKX54406.1 - 0.047 13.9 1.8 0.047 13.9 1.8 2.5 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II Tup_N PF08581.10 EKX54406.1 - 0.05 13.9 7.4 0.12 12.7 2.9 3.0 1 1 2 3 3 3 0 Tup N-terminal Nup88 PF10168.9 EKX54406.1 - 0.093 10.5 5.9 0.13 10.0 5.9 1.3 1 0 0 1 1 1 0 Nuclear pore component HOOK PF05622.12 EKX54406.1 - 0.11 10.6 13.3 0.0099 14.1 8.9 1.4 2 0 0 2 2 2 0 HOOK protein HAP1_N PF04849.13 EKX54406.1 - 0.11 11.6 8.9 0.3 10.2 9.0 1.6 1 1 0 1 1 1 0 HAP1 N-terminal conserved region TMF_DNA_bd PF12329.8 EKX54406.1 - 0.13 12.3 10.9 0.97 9.5 10.8 2.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.10 EKX54406.1 - 0.14 12.4 3.7 0.26 11.5 3.7 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family HALZ PF02183.18 EKX54406.1 - 0.15 12.3 6.5 3 8.1 6.5 2.6 1 1 0 1 1 1 0 Homeobox associated leucine zipper MCU PF04678.13 EKX54406.1 - 0.15 12.1 5.7 0.027 14.6 2.0 1.7 2 0 0 2 2 1 0 Mitochondrial calcium uniporter APG6_N PF17675.1 EKX54406.1 - 0.22 12.0 18.4 0.04 14.5 13.2 2.3 2 1 0 2 2 1 0 Apg6 coiled-coil region PI_PP_I PF18363.1 EKX54406.1 - 0.22 11.7 2.9 0.47 10.7 0.4 2.3 2 1 1 3 3 2 0 Phosphoinositide phosphatase insertion domain Rho_Binding PF08912.11 EKX54406.1 - 0.22 12.3 7.5 0.15 12.9 1.5 2.7 2 0 0 2 2 2 0 Rho Binding ZapB PF06005.12 EKX54406.1 - 0.3 11.6 9.4 0.22 12.0 6.1 2.4 1 1 1 2 2 2 0 Cell division protein ZapB CENP-F_leu_zip PF10473.9 EKX54406.1 - 0.31 11.1 15.6 0.023 14.7 9.6 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_1 PF00170.21 EKX54406.1 - 0.32 11.1 9.7 3.1 8.0 5.0 2.7 1 1 1 2 2 2 0 bZIP transcription factor Med9 PF07544.13 EKX54406.1 - 0.33 11.1 7.6 0.2 11.7 0.5 2.6 3 0 0 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 TPR_MLP1_2 PF07926.12 EKX54406.1 - 0.34 11.0 12.1 0.35 10.9 4.8 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Cep57_CLD_2 PF14197.6 EKX54406.1 - 0.34 11.0 14.4 4.1 7.6 8.1 2.8 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 ATG16 PF08614.11 EKX54406.1 - 0.39 10.9 10.5 4.1 7.6 0.9 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CENP-H PF05837.12 EKX54406.1 - 0.46 10.9 8.9 0.042 14.3 3.6 2.0 2 1 0 2 2 1 0 Centromere protein H (CENP-H) Phage_GPO PF05929.11 EKX54406.1 - 0.49 10.0 2.8 0.77 9.3 2.8 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Exonuc_VII_L PF02601.15 EKX54406.1 - 0.51 9.8 4.6 0.8 9.2 4.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sipho_Gp157 PF05565.11 EKX54406.1 - 0.62 10.1 11.6 0.054 13.5 6.8 1.6 2 0 0 2 2 1 0 Siphovirus Gp157 Fez1 PF06818.15 EKX54406.1 - 0.7 10.3 11.9 0.32 11.4 8.7 1.9 1 1 0 1 1 1 0 Fez1 V_ATPase_I PF01496.19 EKX54406.1 - 0.7 7.7 4.9 1 7.2 4.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Uso1_p115_C PF04871.13 EKX54406.1 - 0.93 9.9 11.8 0.61 10.5 7.6 2.6 2 1 0 2 2 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region PEARLI-4 PF05278.12 EKX54406.1 - 0.93 9.0 8.7 1.1 8.8 2.9 2.3 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) bZIP_2 PF07716.15 EKX54406.1 - 1.1 9.4 11.2 0.36 10.9 2.2 3.2 1 1 2 3 3 3 0 Basic region leucine zipper CLZ PF16526.5 EKX54406.1 - 1.2 9.6 9.6 0.11 12.8 2.4 2.6 2 1 1 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ZapA PF05164.13 EKX54406.1 - 1.2 9.6 4.5 3.4 8.2 4.5 1.7 1 1 0 1 1 1 0 Cell division protein ZapA OmpH PF03938.14 EKX54406.1 - 1.4 9.3 6.4 4.9 7.5 6.3 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) TMPIT PF07851.13 EKX54406.1 - 1.5 8.0 5.7 2.6 7.2 5.3 1.5 1 1 0 1 1 1 0 TMPIT-like protein GTP-bdg_M PF16360.5 EKX54406.1 - 1.5 9.5 5.2 1.3 9.7 1.2 2.6 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region Nsp1_C PF05064.13 EKX54406.1 - 1.7 8.4 9.4 0.17 11.7 3.8 1.9 2 0 0 2 2 2 0 Nsp1-like C-terminal region YabA PF06156.13 EKX54406.1 - 1.8 9.2 10.7 0.65 10.7 7.1 2.2 2 1 0 2 2 1 0 Initiation control protein YabA Phage_GP20 PF06810.11 EKX54406.1 - 1.9 8.3 11.1 0.91 9.3 1.8 2.6 2 1 1 3 3 2 0 Phage minor structural protein GP20 Suppressor_APC PF11414.8 EKX54406.1 - 2.1 8.5 7.1 0.86 9.7 2.2 2.3 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein Spc7 PF08317.11 EKX54406.1 - 2.5 6.9 16.4 0.19 10.6 10.3 2.1 2 1 0 2 2 2 0 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 EKX54406.1 - 3.5 8.3 13.8 1.5 9.5 3.7 3.1 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Csm1_N PF18504.1 EKX54406.1 - 3.5 8.0 13.9 2 8.8 3.7 3.1 2 2 2 4 4 2 0 Csm1 N-terminal domain DUF1664 PF07889.12 EKX54406.1 - 3.6 7.6 5.6 3.8 7.6 1.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 EKX54406.1 - 4.6 7.5 13.1 1.2 9.4 8.2 2.3 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PI3K_P85_iSH2 PF16454.5 EKX54406.1 - 6.3 6.4 16.3 3.2 7.3 10.9 2.6 2 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4200 PF13863.6 EKX54406.1 - 7 7.1 18.1 3.8 7.9 13.2 2.8 2 1 0 2 2 1 0 Domain of unknown function (DUF4200) THOC7 PF05615.13 EKX54406.1 - 8.5 6.7 13.5 12 6.2 7.8 2.7 2 1 1 3 3 3 0 Tho complex subunit 7 BST2 PF16716.5 EKX54406.1 - 8.7 7.0 10.7 0.64 10.6 2.0 2.8 2 1 1 3 3 2 0 Bone marrow stromal antigen 2 PRKG1_interact PF15898.5 EKX54406.1 - 9 7.3 16.9 1.5 9.8 3.9 3.0 2 1 1 3 3 2 0 cGMP-dependent protein kinase interacting domain Methyltr_RsmB-F PF01189.17 EKX54407.1 - 1.1e-29 103.5 0.0 2e-28 99.4 0.0 2.4 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F RRM_1 PF00076.22 EKX54407.1 - 4.4e-05 23.2 0.0 9.4e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNARE PF05739.19 EKX54407.1 - 0.0031 17.5 0.7 0.0031 17.5 0.7 1.9 2 0 0 2 2 2 1 SNARE domain PHO4 PF01384.20 EKX54409.1 - 5.8e-89 298.5 3.3 1.1e-68 231.8 0.0 2.0 1 1 1 2 2 2 2 Phosphate transporter family EF-hand_1 PF00036.32 EKX54410.1 - 0.013 15.0 0.0 6.1 6.6 0.0 2.9 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 EKX54410.1 - 0.017 15.5 0.0 0.091 13.2 0.0 2.4 1 1 0 1 1 1 0 EF-hand domain pair SAM_2 PF07647.17 EKX54410.1 - 0.086 13.0 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) CDC45 PF02724.14 EKX54411.1 - 9.3e-121 404.1 10.6 5.7e-119 398.2 10.6 2.3 1 1 0 1 1 1 1 CDC45-like protein MMADHC PF10229.9 EKX54411.1 - 1.6e-08 34.6 0.0 3.7e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein STAR_dimer PF16544.5 EKX54411.1 - 0.024 14.2 0.1 0.16 11.6 0.0 2.2 2 0 0 2 2 2 0 Homodimerisation region of STAR domain protein Acetyltransf_1 PF00583.25 EKX54412.1 - 1.1e-16 61.1 0.0 1.4e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EKX54412.1 - 1.2e-12 47.9 0.0 1.5e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EKX54412.1 - 1.1e-11 45.0 0.0 2e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EKX54412.1 - 2.2e-05 24.6 0.0 2.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EKX54412.1 - 3.4e-05 23.9 0.0 0.0037 17.3 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EKX54412.1 - 0.00014 21.8 0.0 0.00026 20.9 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EKX54412.1 - 0.001 19.7 0.0 0.0012 19.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 EKX54412.1 - 0.03 13.9 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_CG PF14542.6 EKX54412.1 - 0.089 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 EKX54412.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Aldolase PF01081.19 EKX54413.1 - 4.1e-22 78.6 0.1 4.4e-22 78.5 0.1 1.0 1 0 0 1 1 1 1 KDPG and KHG aldolase FCH PF00611.23 EKX54415.1 - 0.016 15.5 1.6 0.065 13.5 1.6 2.1 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain SRP54 PF00448.22 EKX54415.1 - 0.081 12.5 0.8 0.15 11.7 0.8 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MRP-L28 PF09812.9 EKX54415.1 - 0.28 11.3 3.6 0.45 10.6 1.9 2.1 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L28 CSN5_C PF18323.1 EKX54415.1 - 0.43 11.5 11.6 1.4 9.9 0.1 3.6 3 1 0 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain Sod_Fe_C PF02777.18 EKX54416.1 - 1.1e-41 141.1 0.1 2e-41 140.3 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EKX54416.1 - 1.5e-26 92.7 0.3 3.2e-26 91.6 0.3 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Acetyltransf_1 PF00583.25 EKX54419.1 - 0.022 15.0 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family PseudoU_synth_2 PF00849.22 EKX54420.1 - 2.8e-19 69.7 0.1 1.9e-18 67.0 0.1 1.9 1 1 0 1 1 1 1 RNA pseudouridylate synthase COPIIcoated_ERV PF07970.12 EKX54421.1 - 7.8e-22 78.2 2.3 1.9e-21 77.0 0.0 2.6 2 1 1 3 3 3 1 Endoplasmic reticulum vesicle transporter Thioredoxin PF00085.20 EKX54421.1 - 2.3e-19 69.3 0.1 4.7e-19 68.3 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin ERGIC_N PF13850.6 EKX54421.1 - 9e-15 54.8 0.1 2.2e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) OST3_OST6 PF04756.13 EKX54421.1 - 1e-06 28.3 0.1 3e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EKX54421.1 - 0.00017 22.0 0.1 0.0012 19.3 0.1 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EKX54421.1 - 0.022 15.0 0.1 0.045 13.9 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_8 PF13905.6 EKX54421.1 - 0.099 13.0 0.0 1 9.7 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin-like Pkinase PF00069.25 EKX54422.1 - 2.5e-68 230.3 0.0 4.5e-68 229.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX54422.1 - 3.7e-30 105.1 0.0 5.3e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EKX54422.1 - 6.7e-06 25.3 0.0 2.1e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EKX54422.1 - 0.0048 16.3 0.1 0.0075 15.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX54422.1 - 0.052 13.5 0.4 0.052 13.5 0.4 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 EKX54422.1 - 0.11 12.1 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 TPR_12 PF13424.6 EKX54423.1 - 6.9e-12 45.5 12.1 0.0002 21.6 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX54423.1 - 9.3e-07 28.5 13.6 0.25 11.5 4.9 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EKX54423.1 - 4.8e-06 27.0 8.8 0.045 14.2 0.1 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX54423.1 - 1.1e-05 25.2 10.9 0.055 13.7 3.4 4.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX54423.1 - 1.8e-05 24.8 7.4 1.2 9.7 0.0 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX54423.1 - 0.00014 21.5 17.4 0.036 13.9 5.9 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX54423.1 - 0.00046 20.3 3.5 0.05 13.8 0.2 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX54423.1 - 0.00076 19.3 9.4 0.057 13.5 1.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX54423.1 - 0.0083 16.9 4.7 9.6 7.3 0.0 4.1 3 1 2 5 5 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX54423.1 - 0.03 14.0 13.0 0.47 10.2 0.2 4.1 2 1 2 4 4 4 0 TPR repeat TPR_10 PF13374.6 EKX54423.1 - 0.15 11.9 7.7 0.24 11.3 1.4 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EKX54423.1 - 0.21 12.2 5.8 4.7 7.9 0.0 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX54423.1 - 9.5 7.1 7.1 58 4.6 0.9 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat MCM PF00493.23 EKX54424.1 - 2.6e-101 337.4 0.0 4e-101 336.8 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EKX54424.1 - 8.1e-38 129.1 0.6 1.6e-37 128.2 0.6 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EKX54424.1 - 4.7e-27 94.2 1.0 4.7e-27 94.2 1.0 2.5 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 EKX54424.1 - 5.8e-13 49.3 1.0 3.2e-12 47.0 0.2 2.5 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 EKX54424.1 - 5e-08 33.0 0.0 3.2e-07 30.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EKX54424.1 - 7.5e-08 32.0 0.1 4.9e-05 22.8 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EKX54424.1 - 0.0021 17.9 0.1 0.0084 16.0 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX54424.1 - 0.013 15.9 1.5 0.083 13.3 0.1 3.1 2 1 0 2 2 2 0 AAA ATPase domain Sigma54_activat PF00158.26 EKX54424.1 - 0.03 14.0 0.0 12 5.6 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_32 PF13654.6 EKX54424.1 - 0.037 12.8 0.5 0.072 11.9 0.5 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EKX54424.1 - 0.044 14.2 0.1 0.2 12.1 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF4680 PF15730.5 EKX54424.1 - 0.091 13.1 5.6 0.25 11.7 5.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) CDT1_C PF16679.5 EKX54424.1 - 1.8 9.1 5.8 0.4 11.1 1.1 2.3 2 0 0 2 2 2 0 DNA replication factor Cdt1 C-terminal domain PPR PF01535.20 EKX54425.1 - 7.5e-30 101.1 13.8 1.3e-05 25.1 0.1 10.0 10 0 0 10 10 10 7 PPR repeat PPR_2 PF13041.6 EKX54425.1 - 1.1e-27 95.9 11.2 6.2e-05 23.1 0.0 8.3 3 3 5 8 8 8 8 PPR repeat family PPR_1 PF12854.7 EKX54425.1 - 3.8e-16 58.5 0.0 0.00025 20.7 0.0 7.6 9 0 0 9 9 9 2 PPR repeat PPR_3 PF13812.6 EKX54425.1 - 1.4e-11 44.3 0.8 0.02 15.0 0.0 5.7 3 3 5 8 8 8 7 Pentatricopeptide repeat domain PPR_long PF17177.4 EKX54425.1 - 6.9e-11 41.9 0.0 0.0084 15.5 0.2 3.2 2 1 0 3 3 3 3 Pentacotripeptide-repeat region of PRORP Smr PF01713.21 EKX54425.1 - 9.1e-06 25.9 0.0 2.4e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Smr domain Clathrin PF00637.20 EKX54425.1 - 0.022 14.7 2.1 3.6 7.4 0.2 2.6 2 1 0 2 2 2 0 Region in Clathrin and VPS Ca_bind_SSO6904 PF18249.1 EKX54425.1 - 0.028 14.8 0.6 0.19 12.1 0.1 2.5 2 0 0 2 2 2 0 Calcium binding protein SSO6904 Pox_D2 PF04701.13 EKX54425.1 - 0.037 14.2 0.1 0.075 13.2 0.1 1.4 1 0 0 1 1 1 0 Pox virus D2 protein ATP13 PF12921.7 EKX54425.1 - 0.13 12.1 0.0 0.92 9.4 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ATPase expression TRAM_LAG1_CLN8 PF03798.16 EKX54426.1 - 1.4e-27 96.8 25.1 2.3e-27 96.1 25.1 1.3 1 0 0 1 1 1 1 TLC domain Mago-bind PF09282.10 EKX54427.1 - 2.6e-14 52.8 0.6 2.6e-14 52.8 0.6 2.0 2 0 0 2 2 2 1 Mago binding DUF1664 PF07889.12 EKX54427.1 - 0.077 13.0 5.5 0.062 13.3 3.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TraF_2 PF13729.6 EKX54427.1 - 0.13 11.6 0.2 0.16 11.3 0.2 1.3 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein FHIPEP PF00771.20 EKX54427.1 - 0.73 8.2 4.0 0.85 8.0 4.0 1.1 1 0 0 1 1 1 0 FHIPEP family DUF5320 PF17253.2 EKX54427.1 - 0.78 10.8 10.5 1.6 9.9 2.5 2.7 1 1 1 2 2 2 0 Family of unknown function (DUF5320) Allexi_40kDa PF05549.11 EKX54427.1 - 2.9 7.3 4.4 3.7 7.0 4.4 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein GreA_GreB_N PF03449.15 EKX54427.1 - 6.3 7.0 14.2 0.21 11.8 6.1 2.5 1 1 1 2 2 2 0 Transcription elongation factor, N-terminal Kinesin PF00225.23 EKX54428.1 - 4.5e-47 160.6 0.0 5.1e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX54428.1 - 1.1e-10 41.6 0.0 2.1e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding SH3_9 PF14604.6 EKX54429.1 - 0.0024 17.7 0.0 1.6e+02 2.2 0.0 5.2 6 0 0 6 6 6 0 Variant SH3 domain LRRCT PF01463.24 EKX54429.1 - 0.025 15.1 27.3 18 6.2 0.4 6.4 6 0 0 6 6 6 0 Leucine rich repeat C-terminal domain p47_phox_C PF08944.11 EKX54429.1 - 3.2 7.2 13.6 1.3e+02 2.1 0.3 5.9 6 0 0 6 6 6 0 NADPH oxidase subunit p47Phox, C terminal domain HSBP1 PF06825.12 EKX54430.1 - 0.0065 16.3 1.4 0.016 15.0 1.4 1.7 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Vps55 PF04133.14 EKX54432.1 - 1.8e-23 82.7 9.9 2e-23 82.5 9.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 RRM_1 PF00076.22 EKX54433.1 - 7e-11 41.8 0.0 1.5e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 EKX54433.1 - 0.014 15.4 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain RRM_3 PF08777.11 EKX54433.1 - 0.016 15.3 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif Efg1 PF10153.9 EKX54433.1 - 0.15 12.4 0.1 0.38 11.1 0.1 1.6 1 0 0 1 1 1 0 rRNA-processing protein Efg1 RRM_occluded PF16842.5 EKX54433.1 - 0.21 11.5 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Amidohydro_1 PF01979.20 EKX54434.1 - 1.6e-54 185.5 0.0 2.1e-54 185.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EKX54434.1 - 4.7e-11 42.8 0.0 1.4e-08 34.6 0.0 2.1 1 1 0 2 2 2 2 Amidohydrolase family Pyr_redox_2 PF07992.14 EKX54435.1 - 1e-29 103.7 0.0 8.8e-14 51.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EKX54435.1 - 0.00021 21.8 3.4 0.88 10.2 0.1 3.9 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 EKX54435.1 - 0.00045 20.1 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain K_oxygenase PF13434.6 EKX54435.1 - 0.026 13.7 0.0 1.8 7.6 0.0 2.5 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EKX54435.1 - 0.033 14.2 0.4 4.1 7.4 0.6 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EKX54435.1 - 0.039 14.2 1.8 0.083 13.1 0.4 2.3 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EKX54435.1 - 0.22 11.1 2.0 0.51 9.9 1.6 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase CCDC106 PF15794.5 EKX54437.1 - 0.031 14.0 3.2 0.055 13.2 3.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 bZIP_1 PF00170.21 EKX54437.1 - 0.037 14.1 1.6 0.037 14.1 1.6 1.6 2 0 0 2 2 2 0 bZIP transcription factor ubiquitin PF00240.23 EKX54438.1 - 2.8e-06 27.0 0.0 4.4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 EKX54438.1 - 0.027 15.0 0.0 0.044 14.4 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 EKX54438.1 - 0.035 14.0 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like RIO1 PF01163.22 EKX54439.1 - 9.3e-50 168.8 0.7 1.4e-49 168.3 0.2 1.5 2 0 0 2 2 2 1 RIO1 family Rio2_N PF09202.11 EKX54439.1 - 1.4e-29 102.1 0.3 2.5e-29 101.3 0.3 1.4 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 EKX54439.1 - 7.7e-10 39.1 3.9 0.00021 21.3 0.3 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EKX54439.1 - 2.1e-05 24.0 0.9 0.0029 17.0 0.1 2.6 1 1 1 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EKX54439.1 - 0.0044 16.4 0.8 0.025 13.9 0.8 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EKX54439.1 - 0.0095 14.7 0.0 0.017 13.9 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase DSPc PF00782.20 EKX54441.1 - 3e-17 62.7 0.0 5.6e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EKX54441.1 - 0.0011 19.2 0.0 0.0026 18.0 0.0 1.6 1 0 0 1 1 1 1 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 EKX54441.1 - 0.011 15.9 1.1 0.17 12.0 0.0 2.4 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 EKX54441.1 - 0.097 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ubiquitin_4 PF18036.1 EKX54441.1 - 0.13 12.4 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain DAP3 PF10236.9 EKX54442.1 - 1.1e-23 83.9 0.0 1e-20 74.1 0.0 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 EKX54442.1 - 0.00055 20.4 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain SelB-wing_2 PF09106.11 EKX54442.1 - 0.0053 16.9 0.0 0.1 12.8 0.0 2.6 2 0 0 2 2 2 1 Elongation factor SelB, winged helix ATPase_2 PF01637.18 EKX54442.1 - 0.0079 16.1 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 EKX54442.1 - 0.0081 16.6 0.0 1 9.8 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 EKX54442.1 - 0.19 10.6 0.0 0.41 9.5 0.0 1.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain TPR_2 PF07719.17 EKX54443.1 - 3.1e-13 48.7 0.6 0.0008 19.3 0.0 5.3 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX54443.1 - 4.4e-10 38.9 0.8 0.0074 16.2 0.0 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX54443.1 - 2.8e-09 36.4 0.9 0.00042 20.0 0.0 4.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX54443.1 - 4.1e-09 36.0 3.4 0.0031 17.3 0.0 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX54443.1 - 2.1e-08 33.7 0.4 0.065 13.5 0.0 4.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 EKX54443.1 - 3e-08 33.8 0.0 1.1 10.0 0.0 4.7 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX54443.1 - 7.5e-08 32.6 0.0 0.065 14.1 0.0 5.1 3 2 3 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX54443.1 - 8.9e-08 32.5 0.0 0.0016 18.9 0.0 3.6 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX54443.1 - 1.1e-07 32.4 0.0 0.0015 19.1 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX54443.1 - 6.6e-06 26.1 0.0 0.0035 17.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX54443.1 - 1.8e-05 24.9 2.3 0.21 11.9 0.0 4.1 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EKX54443.1 - 2.6e-05 23.8 0.0 0.002 17.7 0.0 3.4 3 1 1 4 4 4 1 TPR repeat ANAPC3 PF12895.7 EKX54443.1 - 3.9e-05 23.8 1.2 0.0004 20.6 0.1 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EKX54443.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.4 1 1 0 1 1 1 0 MalT-like TPR region TPPII_N PF12583.8 EKX54443.1 - 0.023 15.3 6.1 21 5.7 0.4 4.6 3 2 2 5 5 5 0 Tripeptidyl peptidase II N terminal Fis1_TPR_C PF14853.6 EKX54443.1 - 0.027 14.5 0.1 2.6 8.2 0.0 3.5 3 1 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF4192 PF13830.6 EKX54443.1 - 0.049 13.7 0.3 0.096 12.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) TRAM_LAG1_CLN8 PF03798.16 EKX54444.1 - 7.3e-31 107.5 18.4 1.1e-30 106.9 18.4 1.2 1 0 0 1 1 1 1 TLC domain PspA_IM30 PF04012.12 EKX54445.1 - 0.00047 19.8 8.8 0.00076 19.1 8.8 1.2 1 0 0 1 1 1 1 PspA/IM30 family DUF456 PF04306.13 EKX54445.1 - 1.7 9.0 8.4 0.22 11.8 3.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF456) Gly-zipper_Omp PF13488.6 EKX54445.1 - 9.1 6.4 16.6 0.41 10.7 10.8 1.8 2 0 0 2 2 2 0 Glycine zipper DJ-1_PfpI PF01965.24 EKX54446.1 - 1.3e-39 135.7 0.8 2.4e-39 134.8 0.2 1.6 1 1 1 2 2 2 1 DJ-1/PfpI family GATase_3 PF07685.14 EKX54446.1 - 0.0027 17.4 0.0 0.0038 16.9 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Catalase_C PF18011.1 EKX54446.1 - 0.032 13.9 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 C-terminal domain found in long catalases Peptidase_S8 PF00082.22 EKX54447.1 - 4.2e-79 265.9 0.0 6.4e-79 265.3 0.0 1.3 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.8 EKX54447.1 - 1.2e-53 181.5 0.1 2.6e-53 180.3 0.0 1.5 2 0 0 2 2 2 1 Tripeptidyl peptidase II Peripla_BP_2 PF01497.18 EKX54448.1 - 1.2e-11 44.7 0.0 2.1e-11 43.9 0.0 1.4 1 1 0 1 1 1 1 Periplasmic binding protein Herp-Cyclin PF09241.10 EKX54448.1 - 0.13 13.0 0.0 0.26 11.9 0.0 1.6 1 0 0 1 1 1 0 Herpesviridae viral cyclin Bac_rhodopsin PF01036.18 EKX54449.1 - 5.3e-12 45.8 12.1 7.3e-12 45.3 12.1 1.2 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF2269 PF10027.9 EKX54449.1 - 0.049 13.7 3.4 0.12 12.4 3.4 1.6 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) FhuF_C PF11575.8 EKX54449.1 - 0.19 11.7 1.7 0.47 10.4 0.4 2.3 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Glycos_transf_2 PF00535.26 EKX54450.1 - 3.6e-16 59.4 0.0 5.4e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EKX54450.1 - 1.5e-06 28.3 0.0 2.5e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Rhamno_transf PF11316.8 EKX54450.1 - 0.00024 20.6 0.2 0.00039 19.9 0.2 1.2 1 0 0 1 1 1 1 Putative rhamnosyl transferase Glyco_tranf_2_2 PF10111.9 EKX54450.1 - 0.00031 20.3 0.1 0.00056 19.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EKX54450.1 - 0.058 13.9 0.4 0.14 12.7 0.4 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 2 Patched PF02460.18 EKX54451.1 - 2.5e-107 360.0 0.0 3.2e-107 359.6 0.0 1.0 1 0 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 EKX54451.1 - 1.7e-32 112.4 6.5 1.7e-32 112.4 6.5 3.3 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.19 EKX54451.1 - 0.025 12.3 18.0 0.0036 15.0 13.4 1.7 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family ASH PF15780.5 EKX54452.1 - 4.2e-11 42.9 0.3 0.002 18.3 0.0 4.4 4 0 0 4 4 4 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 EKX54452.1 - 4e-06 26.9 0.0 0.00012 22.2 0.0 2.9 3 0 0 3 3 3 1 Flagellar-associated PapD-like RuvC PF02075.17 EKX54452.1 - 0.054 13.4 0.8 0.12 12.2 0.8 1.5 1 0 0 1 1 1 0 Crossover junction endodeoxyribonuclease RuvC PDZ PF00595.24 EKX54453.1 - 5e-13 49.2 0.1 5.1e-06 26.7 0.0 2.6 2 0 0 2 2 2 2 PDZ domain CAP_C PF08603.11 EKX54453.1 - 8.1e-13 48.3 2.8 1.7e-12 47.2 2.8 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal PDZ_2 PF13180.6 EKX54453.1 - 1.4e-11 44.5 0.1 4.8e-06 26.8 0.0 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EKX54453.1 - 2e-11 43.5 3.3 0.00013 21.8 0.0 3.6 3 0 0 3 3 3 2 PDZ domain TBCC PF07986.12 EKX54453.1 - 8.5e-06 25.5 7.4 2.2e-05 24.1 7.4 1.6 1 1 0 1 1 1 1 Tubulin binding cofactor C Voltage_CLC PF00654.20 EKX54454.1 - 2.7e-58 197.9 23.1 2.9e-58 197.8 21.1 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel ChiW_Ig_like PF18683.1 EKX54454.1 - 0.09 13.0 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 Chitinase W immunoglobulin-like domain HisKA PF00512.25 EKX54454.1 - 0.16 12.0 0.3 13 5.9 0.0 3.1 2 1 0 2 2 2 0 His Kinase A (phospho-acceptor) domain EF-hand_6 PF13405.6 EKX54455.1 - 5.1e-05 22.9 0.1 0.00017 21.2 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 EKX54455.1 - 0.00014 22.3 0.5 0.023 15.1 0.1 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX54455.1 - 0.00064 19.1 0.2 0.0019 17.6 0.0 1.9 2 0 0 2 2 2 1 EF hand DUF5582 PF17819.1 EKX54455.1 - 0.0026 18.2 0.0 0.0052 17.3 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5582) DUF5586 PF17824.1 EKX54455.1 - 0.014 14.5 0.1 0.019 14.1 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5586) EF-hand_5 PF13202.6 EKX54455.1 - 0.029 13.8 0.6 0.097 12.2 0.0 2.1 3 0 0 3 3 3 0 EF hand SNRNP27 PF08648.12 EKX54455.1 - 0.29 11.2 1.6 0.47 10.6 0.2 1.9 1 1 1 2 2 2 0 U4/U6.U5 small nuclear ribonucleoproteins MgtE PF01769.16 EKX54456.1 - 5.2e-25 88.2 8.9 5.2e-25 88.2 8.9 1.6 1 1 1 2 2 2 1 Divalent cation transporter Com_YlbF PF06133.11 EKX54458.1 - 0.016 15.8 1.3 0.016 15.8 1.3 1.7 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Seryl_tRNA_N PF02403.22 EKX54458.1 - 0.41 10.9 6.0 0.11 12.8 2.7 1.8 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Efg1 PF10153.9 EKX54459.1 - 4.8e-24 84.9 10.8 5.3e-24 84.8 10.8 1.0 1 0 0 1 1 1 1 rRNA-processing protein Efg1 PRA-PH PF01503.17 EKX54459.1 - 0.052 14.0 0.8 0.11 13.0 0.8 1.6 1 1 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase TPD52 PF04201.15 EKX54459.1 - 0.061 12.9 1.1 0.072 12.7 1.1 1.1 1 0 0 1 1 1 0 Tumour protein D52 family ARGLU PF15346.6 EKX54459.1 - 0.17 11.8 11.2 0.29 11.0 11.2 1.3 1 1 0 1 1 1 0 Arginine and glutamate-rich 1 HEAT_2 PF13646.6 EKX54461.1 - 3.5e-08 33.7 2.4 0.00088 19.6 0.1 4.1 2 1 1 3 3 3 2 HEAT repeats Arm PF00514.23 EKX54461.1 - 6.7e-06 26.0 6.0 0.26 11.4 0.0 5.4 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.14 EKX54461.1 - 0.0016 17.8 0.3 0.0089 15.3 0.0 2.1 1 1 0 2 2 2 1 V-ATPase subunit H HEAT PF02985.22 EKX54461.1 - 0.002 18.2 7.8 1.2 9.6 0.1 5.2 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 EKX54461.1 - 0.0039 17.2 0.7 0.048 13.7 0.2 2.7 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 UNC45-central PF11701.8 EKX54461.1 - 0.078 12.9 2.3 0.96 9.4 0.7 2.5 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central Hid1 PF12722.7 EKX54463.1 - 2.6e-151 505.5 2.5 1.2e-131 440.5 0.1 2.5 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 EKX54463.1 - 2.1e-146 489.0 0.0 2.8e-146 488.5 0.0 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein PA14 PF07691.12 EKX54464.1 - 2.3e-14 53.4 0.0 1.1e-05 25.3 0.0 4.0 4 0 0 4 4 4 2 PA14 domain B_lectin PF01453.24 EKX54464.1 - 0.041 14.4 0.2 10 6.7 0.0 3.4 4 0 0 4 4 4 0 D-mannose binding lectin TMF_DNA_bd PF12329.8 EKX54465.1 - 0.0039 17.2 2.5 1.4 9.0 0.0 2.7 2 1 0 2 2 2 2 TATA element modulatory factor 1 DNA binding HAUS2 PF15003.6 EKX54465.1 - 0.032 14.0 0.2 0.046 13.4 0.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 ADIP PF11559.8 EKX54465.1 - 0.72 9.9 6.1 0.85 9.7 0.9 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Aa_trans PF01490.18 EKX54466.1 - 1.6e-17 63.3 0.4 1.8e-17 63.2 0.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EKX54466.1 - 3.9e-07 29.5 0.9 4.3e-07 29.3 0.9 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 EKX54467.1 - 1.2e-30 106.5 0.3 1.4e-30 106.3 0.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.13 EKX54467.1 - 0.0052 15.6 0.1 0.009 14.9 0.1 1.4 1 0 0 1 1 1 1 Spore germination protein GRIP PF01465.20 EKX54468.1 - 4.6e-11 42.4 0.0 1.1e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 GRIP domain HA2 PF04408.23 EKX54469.1 - 8.7e-26 90.3 0.0 8.7e-26 90.3 0.0 5.6 4 2 1 5 5 5 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EKX54469.1 - 9.9e-15 54.9 0.3 1.2e-13 51.4 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EKX54469.1 - 2.3e-06 27.5 0.0 6.2e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EKX54469.1 - 7.1e-05 23.1 0.8 0.00036 20.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain PPP4R2 PF09184.11 EKX54469.1 - 0.00017 21.3 6.5 0.00017 21.3 6.5 5.2 4 1 1 5 5 5 1 PPP4R2 SR-25 PF10500.9 EKX54469.1 - 0.0045 16.6 14.1 0.0045 16.6 14.1 4.4 3 1 2 5 5 5 1 Nuclear RNA-splicing-associated protein RsgA_GTPase PF03193.16 EKX54469.1 - 0.028 14.3 0.3 3.3 7.6 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase AAA_19 PF13245.6 EKX54469.1 - 0.064 13.6 1.9 0.11 12.9 0.0 2.3 2 1 1 3 3 3 0 AAA domain Bac_globin PF01152.21 EKX54469.1 - 6.6 6.9 7.5 2.9 8.1 0.1 3.4 4 0 0 4 4 4 0 Bacterial-like globin Metallophos PF00149.28 EKX54472.1 - 6.5e-07 30.1 0.0 7.5e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase TIG PF01833.24 EKX54473.1 - 1.8e-16 60.0 0.0 3.9e-08 33.3 0.0 2.4 2 0 0 2 2 2 2 IPT/TIG domain Ephrin_rec_like PF07699.13 EKX54473.1 - 6.3e-13 48.3 13.3 5.1e-10 39.0 7.4 2.7 1 1 1 2 2 2 2 Putative ephrin-receptor like PDZ PF00595.24 EKX54473.1 - 0.0065 16.8 0.1 0.015 15.6 0.1 1.6 1 0 0 1 1 1 1 PDZ domain LRR_6 PF13516.6 EKX54474.1 - 1.2e-14 53.1 26.8 3.2e-06 26.8 0.1 7.3 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 EKX54474.1 - 1.1e-05 25.6 4.4 0.031 14.7 0.0 3.1 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX54474.1 - 0.0011 18.7 5.7 0.016 14.9 0.1 3.6 3 2 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 EKX54474.1 - 0.0012 19.1 0.4 33 5.6 0.0 4.9 5 0 0 5 5 5 1 Leucine Rich Repeat SoPB_HTH PF18090.1 EKX54474.1 - 0.12 12.5 0.7 15 5.8 0.1 2.9 2 1 1 3 3 3 0 Centromere-binding protein HTH domain ParA PF10609.9 EKX54475.1 - 1.9e-73 247.0 0.1 2.3e-70 236.9 0.1 2.2 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase FeS_assembly_P PF01883.19 EKX54475.1 - 1e-12 48.1 0.5 3e-12 46.5 0.3 2.0 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein AAA_31 PF13614.6 EKX54475.1 - 1.6e-10 41.2 0.2 3.4e-08 33.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain CbiA PF01656.23 EKX54475.1 - 3.4e-10 40.1 0.0 6.8e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 EKX54475.1 - 1.9e-07 30.7 0.1 5.7e-07 29.1 0.1 1.7 1 1 0 1 1 1 1 ATPase MipZ DUF971 PF06155.12 EKX54475.1 - 2.9e-07 31.0 0.0 9.1e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF971) ArsA_ATPase PF02374.15 EKX54475.1 - 1.6e-05 24.3 1.0 0.08 12.1 0.2 2.4 2 1 0 2 2 2 2 Anion-transporting ATPase Fer4_NifH PF00142.18 EKX54475.1 - 0.0089 15.5 0.2 0.03 13.8 0.1 1.8 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family POTRA_1 PF08478.10 EKX54475.1 - 0.029 14.7 0.0 3.8 7.9 0.0 2.8 2 0 0 2 2 2 0 POTRA domain, FtsQ-type MeaB PF03308.16 EKX54475.1 - 0.15 11.0 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB VirC1 PF07015.11 EKX54475.1 - 0.18 11.0 0.3 0.42 9.9 0.1 1.7 2 0 0 2 2 2 0 VirC1 protein zf-AN1 PF01428.16 EKX54477.1 - 4.8e-10 39.4 12.6 4.8e-10 39.4 12.6 2.2 3 0 0 3 3 3 1 AN1-like Zinc finger zf-A20 PF01754.16 EKX54477.1 - 2.2e-07 30.7 5.5 2.2e-07 30.7 5.5 2.1 2 0 0 2 2 2 1 A20-like zinc finger Atg14 PF10186.9 EKX54477.1 - 0.026 13.6 3.5 0.027 13.6 3.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 dsRBD2 PF17842.1 EKX54477.1 - 0.39 10.9 5.9 0.85 9.8 5.9 1.7 1 1 0 1 1 1 0 Double-stranded RNA binding domain 2 Abhydrolase_2 PF02230.16 EKX54478.1 - 2.8e-16 60.0 0.0 3.3e-12 46.7 0.0 2.5 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Fer2 PF00111.27 EKX54478.1 - 2e-06 27.6 1.5 2e-06 27.6 1.5 2.4 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain VIT1 PF01988.19 EKX54478.1 - 0.01 15.7 4.6 0.019 14.8 0.3 2.2 2 0 0 2 2 2 0 VIT family DUF5523 PF17661.1 EKX54478.1 - 0.082 12.6 10.9 0.021 14.5 2.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5523) Fer2_3 PF13085.6 EKX54478.1 - 0.083 12.9 0.1 0.23 11.5 0.1 1.7 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DUF1178 PF06676.11 EKX54478.1 - 0.37 11.2 4.6 18 5.7 1.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) AAA_23 PF13476.6 EKX54478.1 - 3.4 8.1 11.7 0.43 11.1 6.8 1.9 2 0 0 2 2 2 0 AAA domain DUF2722 PF10846.8 EKX54478.1 - 6.8 5.5 12.6 0.61 9.0 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Ion_trans PF00520.31 EKX54479.1 - 1.6e-119 397.6 48.4 4.8e-41 140.6 8.5 5.1 5 0 0 5 5 5 5 Ion transport protein Plasmodium_Vir PF05795.11 EKX54479.1 - 2.1 7.7 7.0 0.11 12.0 0.9 1.7 2 0 0 2 2 2 0 Plasmodium vivax Vir protein C2-C2_1 PF11618.8 EKX54480.1 - 1.5e-10 41.3 0.1 1.8e-06 28.1 0.0 3.5 2 1 0 2 2 2 2 First C2 domain of RPGR-interacting protein 1 Imm7 PF15585.6 EKX54480.1 - 0.38 11.0 5.6 0.1 12.9 0.7 2.6 2 1 1 3 3 3 0 Immunity protein 7 TSC22 PF01166.18 EKX54480.1 - 6.9 7.1 12.5 0.055 13.8 1.4 3.2 3 1 0 3 3 3 0 TSC-22/dip/bun family LPP PF04728.13 EKX54480.1 - 7.4 7.0 12.2 11 6.4 0.2 4.6 5 0 0 5 5 5 0 Lipoprotein leucine-zipper Spc110_C PF18520.1 EKX54480.1 - 9 6.0 6.5 1 9.0 0.6 2.4 3 0 0 3 3 3 0 Spindle pole body component 110 C-terminal domain Cytokin-bind PF09265.10 EKX54481.1 - 0.0075 15.7 2.4 0.017 14.6 2.4 1.5 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding DUF2817 PF10994.8 EKX54481.1 - 0.029 13.8 2.0 0.045 13.2 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2817) Erp_C PF06780.11 EKX54481.1 - 1.2 9.1 10.6 0.1 12.6 2.5 3.0 2 0 0 2 2 2 0 Erp protein C-terminus DUF1664 PF07889.12 EKX54481.1 - 9.7 6.2 46.0 0.22 11.6 7.5 6.8 3 1 3 7 7 7 0 Protein of unknown function (DUF1664) zf-met PF12874.7 EKX54483.1 - 2.6e-05 24.4 2.6 5.7e-05 23.4 2.6 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EKX54483.1 - 0.0015 18.7 2.7 0.0015 18.7 2.7 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EKX54483.1 - 0.0044 17.4 1.4 0.012 16.0 1.1 2.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EKX54483.1 - 0.022 15.6 1.0 0.08 13.8 0.7 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-U1 PF06220.12 EKX54483.1 - 0.11 12.3 0.2 0.2 11.5 0.2 1.4 1 0 0 1 1 1 0 U1 zinc finger DUF3449 PF11931.8 EKX54483.1 - 0.14 11.9 0.2 0.21 11.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) zf-C2H2_6 PF13912.6 EKX54483.1 - 0.32 11.1 6.4 1.3 9.1 3.3 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger NHL PF01436.21 EKX54484.1 - 1.7e-47 157.1 14.7 2.2e-09 36.9 0.1 6.5 6 0 0 6 6 6 6 NHL repeat DUF5128 PF17170.4 EKX54484.1 - 8.3e-20 71.2 0.8 0.00061 19.0 0.2 5.0 1 1 4 5 5 5 4 6-bladed beta-propeller SGL PF08450.12 EKX54484.1 - 2.8e-14 53.3 5.0 0.00015 21.5 0.1 5.0 1 1 4 5 5 5 5 SMP-30/Gluconolactonase/LRE-like region SBBP PF06739.11 EKX54484.1 - 6e-06 26.2 3.1 4.8 7.3 0.0 5.1 5 0 0 5 5 5 2 Beta-propeller repeat Phytase-like PF13449.6 EKX54484.1 - 4.9e-05 23.4 0.2 4.4 7.2 0.0 4.6 4 1 0 4 4 4 1 Esterase-like activity of phytase DUF4934 PF16288.5 EKX54484.1 - 7.2e-05 22.6 0.2 0.99 9.4 0.0 3.2 2 1 0 3 3 3 1 Domain of unknown function (DUF4934) Ldl_recept_b PF00058.17 EKX54484.1 - 0.00031 21.2 0.2 3.6 8.1 0.1 4.9 4 2 0 4 4 4 1 Low-density lipoprotein receptor repeat class B Redoxin PF08534.10 EKX54484.1 - 0.00032 20.4 0.1 5.8 6.6 0.0 3.8 3 1 1 4 4 4 2 Redoxin DUF4988 PF16378.5 EKX54484.1 - 0.0074 16.0 0.2 0.032 13.9 0.1 2.0 1 1 1 2 2 2 1 Domain of unknown function TolB_like PF15869.5 EKX54484.1 - 0.023 13.9 0.0 0.16 11.2 0.0 2.1 1 1 1 2 2 2 0 TolB-like 6-blade propeller-like LPD18 PF18832.1 EKX54484.1 - 0.033 14.3 1.1 7.1 6.8 0.1 3.3 3 0 0 3 3 3 0 Large polyvalent protein-associated domain 18 SdiA-regulated PF06977.11 EKX54484.1 - 0.2 10.8 0.0 4.5 6.4 0.0 2.9 2 1 3 5 5 5 0 SdiA-regulated VCBS PF13517.6 EKX54484.1 - 1.6 9.4 7.8 10 6.8 0.5 4.2 2 2 1 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TPR_12 PF13424.6 EKX54485.1 - 1.4e-94 310.4 34.8 2.9e-12 46.7 0.5 10.9 7 2 4 11 11 11 11 Tetratricopeptide repeat TPR_1 PF00515.28 EKX54485.1 - 8.8e-70 227.9 35.8 1.2e-06 28.1 0.5 16.4 17 1 0 17 17 16 12 Tetratricopeptide repeat TPR_2 PF07719.17 EKX54485.1 - 1.9e-62 202.4 32.2 6.6e-05 22.7 0.2 16.6 16 0 0 16 16 16 14 Tetratricopeptide repeat TPR_7 PF13176.6 EKX54485.1 - 1e-53 175.5 30.7 6e-07 29.1 0.2 16.8 17 0 0 17 17 17 9 Tetratricopeptide repeat TPR_8 PF13181.6 EKX54485.1 - 1.6e-53 174.4 30.8 0.00016 21.6 0.2 17.0 17 1 1 18 18 17 11 Tetratricopeptide repeat TPR_10 PF13374.6 EKX54485.1 - 3e-51 170.0 26.3 2.3e-06 27.3 0.2 16.0 18 0 0 18 18 17 11 Tetratricopeptide repeat SNAP PF14938.6 EKX54485.1 - 8.4e-24 84.5 17.3 1.4e-06 28.0 0.4 5.8 3 1 3 6 6 6 5 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 EKX54485.1 - 1.4e-22 78.8 20.0 0.018 15.6 0.2 13.6 16 0 0 16 16 12 4 Tetratricopeptide repeat TPR_14 PF13428.6 EKX54485.1 - 1.8e-21 75.0 16.4 0.62 11.0 0.1 15.6 15 2 3 18 18 15 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX54485.1 - 2.6e-20 72.8 5.8 0.0016 19.0 0.1 10.1 9 3 1 10 10 9 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EKX54485.1 - 6.2e-19 68.5 10.2 1.9e-05 24.2 0.5 6.4 1 1 5 7 7 7 4 MalT-like TPR region TPR_9 PF13371.6 EKX54485.1 - 3.7e-12 46.2 14.7 0.33 11.1 0.3 10.2 6 4 3 10 10 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX54485.1 - 4.6e-12 45.4 13.5 4.4 7.1 0.0 11.7 10 1 1 11 11 11 2 TPR repeat TPR_17 PF13431.6 EKX54485.1 - 3.6e-10 39.5 19.7 0.78 10.3 0.0 12.2 13 0 0 13 13 11 2 Tetratricopeptide repeat RPN7 PF10602.9 EKX54485.1 - 4.4e-10 39.5 15.1 0.0021 17.8 0.3 6.9 3 2 2 6 6 6 3 26S proteasome subunit RPN7 TPR_19 PF14559.6 EKX54485.1 - 4.5e-09 36.7 21.0 0.0015 19.0 0.2 9.6 8 2 3 11 11 9 2 Tetratricopeptide repeat TPR_4 PF07721.14 EKX54485.1 - 2.1e-08 34.0 0.5 3 8.7 0.0 8.3 8 0 0 8 8 6 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 EKX54485.1 - 4.2e-07 29.3 8.9 10 5.7 0.0 9.5 13 1 0 13 13 10 0 SHNi-TPR DUF3856 PF12968.7 EKX54485.1 - 2.2e-06 27.8 15.3 0.21 11.6 0.1 7.3 2 1 4 7 7 7 1 Domain of Unknown Function (DUF3856) ANAPC5 PF12862.7 EKX54485.1 - 5.6e-06 26.3 3.9 10 6.3 0.0 7.3 5 4 2 7 7 7 0 Anaphase-promoting complex subunit 5 TPR_3 PF07720.12 EKX54485.1 - 7.2e-05 22.7 3.2 0.82 9.7 0.1 5.2 5 0 0 5 5 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX54485.1 - 9.4e-05 22.6 24.6 1.1 9.5 0.2 8.4 5 3 4 9 9 9 3 Anaphase-promoting complex, cyclosome, subunit 3 DUF2225 PF09986.9 EKX54485.1 - 0.0001 22.1 8.2 8.1 6.1 0.2 5.8 3 2 1 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.18 EKX54485.1 - 0.00013 22.0 7.4 3 8.0 0.0 8.0 8 1 0 9 9 7 1 MIT (microtubule interacting and transport) domain ComR_TPR PF18710.1 EKX54485.1 - 0.00013 21.6 0.4 0.11 12.0 0.0 4.6 3 2 1 4 4 4 1 ComR tetratricopeptide DUF4810 PF16068.5 EKX54485.1 - 0.00057 20.4 5.4 88 3.7 0.0 7.5 8 1 0 9 9 8 0 Domain of unknown function (DUF4810) PPR PF01535.20 EKX54485.1 - 0.00088 19.4 13.4 20 5.7 0.0 8.8 10 0 0 10 10 7 0 PPR repeat DUF5113 PF17140.4 EKX54485.1 - 0.0013 18.5 0.7 0.05 13.4 0.1 3.8 3 1 1 4 4 4 1 Domain of unknown function (DUF5113) TPR_20 PF14561.6 EKX54485.1 - 0.0057 17.0 3.2 8.5 6.8 0.0 5.4 5 1 0 5 5 4 0 Tetratricopeptide repeat zf-C5HC2 PF02928.16 EKX54485.1 - 0.012 16.0 0.1 3.4 8.1 0.1 3.2 2 0 0 2 2 2 0 C5HC2 zinc finger SPO22 PF08631.10 EKX54485.1 - 0.047 13.2 10.1 0.38 10.2 0.0 5.5 4 1 1 5 5 5 0 Meiosis protein SPO22/ZIP4 like BTAD PF03704.17 EKX54485.1 - 0.053 13.9 12.1 6.9 7.1 0.1 7.1 5 3 2 8 8 6 0 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 EKX54485.1 - 0.7 10.0 12.7 5.1 7.2 0.1 6.9 8 0 0 8 8 7 0 Fis1 C-terminal tetratricopeptide repeat Bac_rhodopsin PF01036.18 EKX54486.1 - 8.5e-25 87.6 18.0 9.7e-25 87.5 18.0 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF21 PF01595.20 EKX54486.1 - 0.085 12.6 2.4 0.15 11.7 2.4 1.5 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain DUF4064 PF13273.6 EKX54486.1 - 1.1 9.6 11.9 1.1 9.6 5.8 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Aminotran_5 PF00266.19 EKX54487.1 - 1.6e-11 43.8 0.0 2.5e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DUF2052 PF09747.9 EKX54488.1 - 1.9e-33 116.3 19.5 1.9e-33 116.3 19.5 3.3 2 1 0 2 2 2 1 Coiled-coil domain containing protein (DUF2052) Peptidase_C48 PF02902.19 EKX54489.1 - 5.3e-14 52.6 0.0 1.1e-13 51.5 0.0 1.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SWIM PF04434.17 EKX54489.1 - 0.0085 15.7 0.0 0.023 14.3 0.0 1.8 1 0 0 1 1 1 1 SWIM zinc finger zf-CCHC_4 PF14392.6 EKX54489.1 - 0.092 12.5 0.3 0.23 11.2 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle Closter_coat PF01785.17 EKX54490.1 - 0.11 11.7 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Closterovirus coat protein Astro_capsid_p PF12226.8 EKX54491.1 - 2.1 7.4 8.5 3.4 6.7 8.5 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DNA_pol_phi PF04931.13 EKX54491.1 - 4.7 5.2 13.7 6.6 4.7 13.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 EKX54491.1 - 4.9 5.3 11.1 6.1 5.0 11.1 1.2 1 0 0 1 1 1 0 CDC45-like protein HEAT_2 PF13646.6 EKX54496.1 - 3.8e-05 24.0 13.6 0.0012 19.2 0.5 4.8 4 1 1 5 5 5 2 HEAT repeats CLASP_N PF12348.8 EKX54496.1 - 0.0011 18.6 1.5 0.44 10.1 0.5 4.4 3 2 1 4 4 4 1 CLASP N terminal Cnd1 PF12717.7 EKX54496.1 - 0.0013 18.9 0.3 0.36 10.9 0.0 3.7 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EKX54496.1 - 0.031 14.9 0.1 42 4.8 0.0 4.0 3 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region K_channel_TID PF07941.11 EKX54496.1 - 0.22 12.0 6.9 0.72 10.4 6.9 1.8 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain HEAT_EZ PF13513.6 EKX54496.1 - 0.44 11.1 9.9 13 6.4 0.1 5.5 4 1 1 5 5 5 0 HEAT-like repeat HEAT PF02985.22 EKX54496.1 - 6.4 7.3 18.7 0.14 12.4 0.4 6.6 8 0 0 8 8 8 0 HEAT repeat CutA1 PF03091.15 EKX54497.1 - 1.8e-36 123.9 0.1 2.1e-36 123.8 0.1 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein TPR_2 PF07719.17 EKX54498.1 - 0.0016 18.4 0.1 1.3 9.3 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EKX54498.1 - 0.0035 17.6 5.5 0.021 15.1 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TIP49 PF06068.13 EKX54499.1 - 6e-159 528.9 1.3 6e-159 528.9 1.3 1.5 2 0 0 2 2 2 1 TIP49 P-loop domain TIP49_C PF17856.1 EKX54499.1 - 2.8e-25 88.2 0.3 6.9e-25 87.0 0.3 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EKX54499.1 - 3.2e-08 34.1 0.7 4.1e-05 24.0 0.2 2.8 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EKX54499.1 - 5.8e-06 26.1 0.4 0.0089 15.8 0.1 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EKX54499.1 - 1.1e-05 25.9 0.3 0.00012 22.5 0.3 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EKX54499.1 - 2.6e-05 24.2 0.4 0.0025 17.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) DnaB_C PF03796.15 EKX54499.1 - 5.3e-05 22.7 0.2 0.0001 21.7 0.2 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 EKX54499.1 - 7.6e-05 23.0 0.3 0.21 11.9 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.6 EKX54499.1 - 0.0001 22.7 2.0 0.0013 19.1 2.0 2.3 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EKX54499.1 - 0.00014 21.3 1.1 0.003 17.0 0.4 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EKX54499.1 - 0.00092 18.8 0.1 0.0022 17.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EKX54499.1 - 0.0011 18.7 0.1 0.72 9.5 0.1 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain ATPase PF06745.13 EKX54499.1 - 0.0077 15.6 1.2 0.01 15.2 0.1 1.8 2 0 0 2 2 2 1 KaiC Zeta_toxin PF06414.12 EKX54499.1 - 0.015 14.6 0.4 0.03 13.6 0.4 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 EKX54499.1 - 0.017 14.7 0.1 0.28 10.7 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2075 PF09848.9 EKX54499.1 - 0.018 14.3 0.0 0.036 13.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Aida_N PF08910.10 EKX54499.1 - 0.024 15.0 0.3 0.081 13.3 0.2 1.9 2 0 0 2 2 1 0 Aida N-terminus NACHT PF05729.12 EKX54499.1 - 0.028 14.3 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 EKX54499.1 - 0.039 14.5 0.8 0.077 13.5 0.8 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EKX54499.1 - 0.058 13.6 0.1 0.15 12.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain YtkA PF13115.6 EKX54499.1 - 0.062 13.9 0.0 0.2 12.3 0.0 1.8 1 0 0 1 1 1 0 YtkA-like GvpD PF07088.11 EKX54499.1 - 0.063 11.9 0.0 0.098 11.3 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein AAA_11 PF13086.6 EKX54499.1 - 0.077 12.8 0.4 0.15 11.8 0.4 1.7 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 EKX54499.1 - 0.077 13.0 0.2 4.2 7.3 0.1 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TsaE PF02367.17 EKX54499.1 - 0.085 12.9 0.3 0.25 11.3 0.3 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DNA_pol3_delta2 PF13177.6 EKX54499.1 - 0.11 12.3 0.0 0.8 9.5 0.0 2.3 1 1 0 1 1 1 0 DNA polymerase III, delta subunit Patatin PF01734.22 EKX54501.1 - 1.2e-11 45.2 2.6 1.2e-10 41.9 2.6 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase Myb_DNA-binding PF00249.31 EKX54502.1 - 9.5e-11 41.7 0.0 1.2e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EKX54502.1 - 0.032 14.1 0.1 0.041 13.8 0.1 1.2 1 0 0 1 1 1 0 Myb DNA-binding like Csm1_N PF18504.1 EKX54503.1 - 0.021 15.2 0.4 0.047 14.0 0.4 1.5 1 0 0 1 1 1 0 Csm1 N-terminal domain MutS_V PF00488.21 EKX54504.1 - 1.4e-68 230.6 0.5 8.4e-58 195.5 0.0 2.3 2 0 0 2 2 2 2 MutS domain V MutS_III PF05192.18 EKX54504.1 - 2.3e-34 119.3 0.0 7.3e-34 117.7 0.0 1.9 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EKX54504.1 - 1e-32 112.7 0.1 2.3e-32 111.6 0.1 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EKX54504.1 - 4.8e-10 39.8 0.8 1.7e-09 38.0 0.0 2.4 2 1 0 2 2 2 1 MutS domain II LBR_tudor PF09465.10 EKX54504.1 - 0.00013 21.7 0.0 0.00034 20.4 0.0 1.7 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain MutS_IV PF05190.18 EKX54504.1 - 0.0091 16.3 0.5 0.091 13.1 0.1 2.5 2 0 0 2 2 2 1 MutS family domain IV Hrs_helical PF12210.8 EKX54504.1 - 0.021 15.3 0.2 0.066 13.8 0.2 1.8 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Rad9_Rad53_bind PF08605.10 EKX54504.1 - 0.16 12.2 0.1 21 5.3 0.0 2.4 2 0 0 2 2 2 0 Fungal Rad9-like Rad53-binding AAA PF00004.29 EKX54505.1 - 7.1e-19 68.5 0.1 1.5e-18 67.5 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 EKX54505.1 - 1.1e-12 48.0 0.6 1.2e-10 41.4 0.6 2.6 1 1 0 1 1 1 1 AAA lid domain DUF815 PF05673.13 EKX54505.1 - 2.9e-05 23.3 0.2 0.0021 17.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 EKX54505.1 - 5.7e-05 23.6 0.3 0.00012 22.5 0.3 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 EKX54505.1 - 0.00011 22.4 0.1 0.00018 21.7 0.1 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EKX54505.1 - 0.00026 20.5 0.8 0.0088 15.4 0.2 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EKX54505.1 - 0.00048 19.9 0.8 0.044 13.5 0.3 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_30 PF13604.6 EKX54505.1 - 0.0017 18.1 1.2 0.004 16.9 1.2 1.7 1 1 0 1 1 1 1 AAA domain CRAL_TRIO_2 PF13716.6 EKX54505.1 - 0.0037 17.4 0.0 0.006 16.7 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain AAA_22 PF13401.6 EKX54505.1 - 0.0062 16.8 0.1 3.1 8.1 0.1 2.4 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 EKX54505.1 - 0.011 16.1 0.0 0.083 13.3 0.0 2.2 2 1 0 2 2 2 0 RNA helicase AAA_5 PF07728.14 EKX54505.1 - 0.018 15.0 0.4 0.059 13.4 0.4 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Parvo_NS1 PF01057.17 EKX54505.1 - 0.024 13.8 0.0 0.053 12.6 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_18 PF13238.6 EKX54505.1 - 0.024 15.2 0.0 0.024 15.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain Viral_helicase1 PF01443.18 EKX54505.1 - 0.035 13.8 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase APS_kinase PF01583.20 EKX54505.1 - 0.04 13.8 0.1 0.074 12.9 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_7 PF12775.7 EKX54505.1 - 0.048 13.2 0.0 0.097 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EKX54505.1 - 0.051 13.3 0.1 0.092 12.5 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ResIII PF04851.15 EKX54505.1 - 0.088 12.8 0.2 0.27 11.2 0.2 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EKX54505.1 - 0.11 12.9 0.5 0.23 11.8 0.4 1.9 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EKX54505.1 - 0.11 12.2 0.1 0.44 10.3 0.1 2.0 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 EKX54505.1 - 0.13 12.3 0.1 0.98 9.5 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain TrwB_AAD_bind PF10412.9 EKX54505.1 - 0.15 10.9 0.6 1.2 8.0 0.1 2.2 1 1 1 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FliG_N PF14842.6 EKX54505.1 - 0.36 11.4 2.2 0.96 10.0 0.1 2.6 3 1 1 4 4 2 0 FliG N-terminal domain AAA_28 PF13521.6 EKX54505.1 - 0.9 9.8 3.3 0.46 10.7 0.5 2.1 2 1 0 2 2 1 0 AAA domain Ank_4 PF13637.6 EKX54506.1 - 2e-19 69.7 0.5 6.1e-12 45.8 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX54506.1 - 6.7e-15 55.4 0.3 1.8e-14 54.0 0.4 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX54506.1 - 5.5e-14 51.9 0.4 3.2e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EKX54506.1 - 4.5e-12 45.9 0.2 1.8e-06 28.1 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX54506.1 - 2.3e-11 42.9 0.1 4.4e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat DUF3447 PF11929.8 EKX54506.1 - 0.015 15.2 0.0 4.8 7.2 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) Ephrin_rec_like PF07699.13 EKX54508.1 - 2.9e-08 33.3 30.4 2.5e-05 23.9 1.3 3.5 1 1 2 3 3 3 3 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX54508.1 - 0.00022 21.6 27.4 0.0033 17.8 6.8 3.7 2 1 0 3 3 3 2 TNFR/NGFR cysteine-rich region NCD3G PF07562.14 EKX54508.1 - 0.0003 20.7 23.8 0.0043 17.0 0.3 3.3 1 1 2 3 3 3 3 Nine Cysteines Domain of family 3 GPCR DUF2318 PF10080.9 EKX54508.1 - 0.37 10.9 18.2 0.081 13.1 6.0 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) Laminin_B PF00052.18 EKX54509.1 - 1.2e-07 31.7 0.0 2.6e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Laminin B (Domain IV) DsrC PF04358.13 EKX54510.1 - 0.033 14.7 0.0 0.075 13.6 0.0 1.6 1 0 0 1 1 1 0 DsrC like protein NUDIX PF00293.28 EKX54511.1 - 8.7e-14 51.7 0.0 2.2e-13 50.4 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain NUDIX-like PF09296.11 EKX54511.1 - 7.3e-08 33.0 0.0 1.7e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 EKX54511.1 - 0.00048 19.7 3.3 0.001 18.7 3.3 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.6 EKX54511.1 - 0.043 13.2 5.7 0.73 9.3 0.3 2.8 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 EKX54511.1 - 0.047 13.7 0.5 0.086 12.9 0.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-MYND PF01753.18 EKX54511.1 - 0.48 10.6 2.5 1 9.5 2.5 1.5 1 0 0 1 1 1 0 MYND finger DUF35_N PF12172.8 EKX54511.1 - 0.75 9.7 4.4 9.8 6.2 0.1 2.6 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Sec1 PF00995.23 EKX54512.1 - 3.2e-114 383.2 0.0 3.7e-114 383.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Acyl-CoA_ox_N PF14749.6 EKX54512.1 - 0.016 15.7 0.3 0.14 12.7 0.3 2.2 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal NODP PF07684.12 EKX54512.1 - 0.14 12.4 0.3 0.46 10.7 0.0 1.9 2 0 0 2 2 2 0 NOTCH protein Sulfotransfer_2 PF03567.14 EKX54513.1 - 3.5e-12 46.8 0.6 1.8e-10 41.1 0.6 2.4 1 1 0 1 1 1 1 Sulfotransferase family O-FucT PF10250.9 EKX54513.1 - 0.044 13.5 0.0 5.7 6.5 0.0 2.8 3 0 0 3 3 3 0 GDP-fucose protein O-fucosyltransferase Frtz PF11768.8 EKX54514.1 - 0.0038 15.6 0.0 0.0051 15.2 0.0 1.2 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz CID_GANP PF16766.5 EKX54514.1 - 0.11 12.7 1.8 0.16 12.1 0.1 2.1 2 0 0 2 2 2 0 Binding region of GANP to ENY2 Robl_LC7 PF03259.17 EKX54515.1 - 1.9e-27 94.8 0.0 2.2e-27 94.7 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 EKX54515.1 - 0.00012 21.9 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 UPF0176_N PF17773.1 EKX54515.1 - 0.024 15.0 0.0 0.028 14.8 0.0 1.1 1 0 0 1 1 1 0 UPF0176 acylphosphatase like domain IQ PF00612.27 EKX54516.1 - 3e-10 39.0 21.1 0.0055 16.4 0.2 5.7 5 0 0 5 5 5 4 IQ calmodulin-binding motif PKD_channel PF08016.12 EKX54516.1 - 7.7e-09 34.7 4.7 6e-06 25.2 0.0 2.7 2 0 0 2 2 2 2 Polycystin cation channel PDZ_2 PF13180.6 EKX54517.1 - 1e-07 32.1 0.1 2.1e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX54517.1 - 6.1e-06 26.5 0.0 1.3e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX54517.1 - 0.0043 16.9 0.0 0.0075 16.1 0.0 1.4 1 0 0 1 1 1 1 PDZ domain cobW PF02492.19 EKX54518.1 - 3.7e-45 153.7 0.9 4.8e-45 153.3 0.9 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 EKX54518.1 - 0.00038 20.4 0.0 0.00074 19.5 0.0 1.4 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea MeaB PF03308.16 EKX54518.1 - 0.00044 19.3 0.1 0.14 11.2 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 EKX54518.1 - 0.0026 17.9 0.1 0.0049 17.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EKX54518.1 - 0.0031 18.0 0.1 0.01 16.4 0.0 1.9 2 1 0 2 2 2 1 AAA domain MobB PF03205.14 EKX54518.1 - 0.0073 16.2 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 EKX54518.1 - 0.0082 16.4 0.3 0.018 15.3 0.3 1.9 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EKX54518.1 - 0.016 14.9 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 EKX54518.1 - 0.02 13.9 0.1 0.044 12.8 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 EKX54518.1 - 0.046 14.1 0.0 0.088 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 EKX54518.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.17 EKX54518.1 - 0.13 12.0 1.1 0.59 9.9 1.1 2.2 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein CobW_C PF07683.14 EKX54519.1 - 4.5e-12 45.7 0.0 5.4e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain SAPS PF04499.15 EKX54521.1 - 1e-54 186.2 17.3 4.9e-30 104.8 0.9 4.3 2 1 3 5 5 5 3 SIT4 phosphatase-associated protein Rcd1 PF04078.13 EKX54521.1 - 0.0019 17.5 0.7 0.0059 15.9 0.1 2.0 2 0 0 2 2 2 1 Cell differentiation family, Rcd1-like IES5 PF17335.2 EKX54521.1 - 0.058 13.7 1.5 0.21 11.9 0.1 2.7 2 1 1 3 3 3 0 Ino80 complex subunit 5 TCR PF03638.15 EKX54522.1 - 5.7e-24 84.2 48.6 3.7e-12 46.3 21.1 2.1 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain preSET_CXC PF18264.1 EKX54522.1 - 3.5 8.2 48.8 5.2 7.6 20.2 2.4 2 0 0 2 2 2 0 CXC domain MSL2-CXC PF16682.5 EKX54522.1 - 7.3 6.8 53.5 1.7 8.9 23.4 3.2 2 2 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 DUF563 PF04577.14 EKX54523.1 - 3.1e-19 69.9 0.1 5.3e-19 69.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DAO PF01266.24 EKX54524.1 - 1.4e-22 80.7 2.1 1.9e-22 80.4 2.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EKX54524.1 - 0.00034 20.7 0.3 0.0019 18.2 0.2 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EKX54524.1 - 0.011 14.9 1.2 0.014 14.5 1.2 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 EKX54524.1 - 0.016 14.5 0.2 0.029 13.6 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EKX54524.1 - 0.043 14.0 0.9 0.12 12.6 0.2 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Merozoite_SPAM PF07133.11 EKX54525.1 - 8.5 6.3 16.6 11 5.9 16.6 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) BolA PF01722.18 EKX54527.1 - 1.1e-15 57.6 0.0 2.9e-15 56.3 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein DnaJ_CXXCXGXG PF00684.19 EKX54528.1 - 0.0077 16.6 7.5 0.015 15.6 5.3 2.1 1 1 1 2 2 2 2 DnaJ central domain Anti-TRAP PF15777.5 EKX54528.1 - 0.24 11.4 4.1 8.4 6.4 4.1 2.4 1 1 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-C3HC4_3 PF13920.6 EKX54529.1 - 0.00018 21.3 13.9 0.00018 21.3 13.9 4.7 3 2 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.26 EKX54529.1 - 0.01 16.2 32.4 0.02 15.3 4.1 6.3 6 1 0 6 6 6 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EKX54529.1 - 0.013 15.5 3.1 0.013 15.5 3.1 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EKX54529.1 - 0.046 14.6 2.5 0.046 14.6 2.5 7.9 8 1 0 8 8 8 0 C2H2-type zinc finger zf-met PF12874.7 EKX54529.1 - 0.051 14.0 19.0 0.18 12.2 0.7 6.0 7 0 0 7 7 7 0 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 EKX54529.1 - 5 7.1 9.4 14 5.6 0.2 4.0 4 1 0 4 4 4 0 C2H2 type zinc-finger (1 copy) YjeF_N PF03853.15 EKX54530.1 - 2.6e-40 138.1 0.0 3.1e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 YjeF-related protein N-terminus PH PF00169.29 EKX54531.1 - 3.2e-15 56.5 1.2 6.6e-15 55.5 0.4 2.0 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 EKX54531.1 - 1.2e-05 25.7 6.9 1.2e-05 25.7 6.9 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain Herpes_BLRF2 PF05812.12 EKX54532.1 - 0.012 15.7 0.3 0.018 15.2 0.3 1.3 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Csm1_N PF18504.1 EKX54532.1 - 0.16 12.3 0.8 0.22 11.9 0.8 1.2 1 0 0 1 1 1 0 Csm1 N-terminal domain Hydrolase_4 PF12146.8 EKX54535.1 - 8.1e-11 41.6 0.1 1.3e-08 34.4 0.2 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EKX54535.1 - 2.2e-05 25.2 0.1 4.1e-05 24.3 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 EKX54535.1 - 4.4e-05 23.2 1.5 0.00023 20.9 2.3 1.7 1 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 EKX54535.1 - 0.0034 16.9 0.2 0.037 13.5 0.2 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EKX54535.1 - 0.0036 17.0 0.0 0.01 15.5 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EKX54535.1 - 0.061 13.2 0.0 0.085 12.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold HTH_9 PF08221.11 EKX54536.1 - 6.2e-17 61.4 0.8 6.2e-12 45.4 0.3 3.9 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 EKX54536.1 - 2e-08 34.4 0.0 6.4e-08 32.7 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 EKX54536.1 - 0.00075 19.3 4.8 0.73 9.7 0.0 3.4 2 1 1 3 3 3 2 TFIIE alpha subunit TrmB PF01978.19 EKX54536.1 - 0.0072 16.2 0.1 0.47 10.4 0.0 3.2 4 0 0 4 4 4 1 Sugar-specific transcriptional regulator TrmB UCH PF00443.29 EKX54537.1 - 8.6e-19 68.0 0.0 1e-18 67.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EKX54537.1 - 0.00015 21.5 0.0 0.00017 21.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase FKBP_C PF00254.28 EKX54538.1 - 1.7e-28 98.8 0.0 4.8e-14 52.5 0.0 3.8 4 0 0 4 4 4 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 EKX54538.1 - 1.1e-06 28.3 0.1 5.4e-05 23.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX54538.1 - 0.00011 21.9 0.5 0.00072 19.3 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX54538.1 - 0.00038 20.5 0.5 0.00089 19.3 0.5 1.6 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 EKX54538.1 - 0.0054 16.9 0.5 0.011 15.9 0.1 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX54538.1 - 0.037 14.3 0.0 0.13 12.6 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat Phage_lysis PF03245.13 EKX54539.1 - 0.2 11.8 9.4 0.19 11.8 3.5 2.6 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein PDZ PF00595.24 EKX54540.1 - 2.7e-14 53.2 0.3 2.8e-09 37.2 0.0 3.8 2 1 1 3 3 3 2 PDZ domain PDZ_6 PF17820.1 EKX54540.1 - 6.6e-09 35.5 3.5 1.4e-05 24.8 0.3 3.3 3 1 0 3 3 3 2 PDZ domain PDZ_2 PF13180.6 EKX54540.1 - 4.7e-08 33.2 0.2 0.00028 21.2 0.1 2.9 2 0 0 2 2 2 2 PDZ domain SPRY PF00622.28 EKX54540.1 - 0.0015 18.6 0.0 0.0055 16.8 0.0 1.9 2 0 0 2 2 2 1 SPRY domain DsrH PF04077.12 EKX54540.1 - 0.065 13.4 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 DsrH like protein Tricorn_PDZ PF14685.6 EKX54540.1 - 0.16 12.0 0.2 0.83 9.7 0.1 2.2 2 0 0 2 2 2 0 Tricorn protease PDZ domain EVE PF01878.18 EKX54541.1 - 2.7e-48 163.6 0.1 3.3e-48 163.4 0.1 1.1 1 0 0 1 1 1 1 EVE domain ImmE5 PF11480.8 EKX54541.1 - 0.086 13.3 0.1 0.16 12.5 0.1 1.4 1 0 0 1 1 1 0 Colicin-E5 Imm protein EF-hand_6 PF13405.6 EKX54542.1 - 3.8e-11 42.0 1.3 0.0068 16.3 0.0 3.8 2 1 1 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 EKX54542.1 - 1.1e-08 35.4 0.8 0.0033 17.8 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX54542.1 - 2.1e-08 33.1 9.6 0.016 14.7 0.0 4.0 4 1 1 5 5 5 3 EF hand EF-hand_8 PF13833.6 EKX54542.1 - 0.0002 21.1 5.6 0.26 11.2 0.1 3.6 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX54542.1 - 0.0025 17.2 2.9 0.35 10.4 0.3 3.9 4 0 0 4 4 4 1 EF hand Helicase_PWI PF18149.1 EKX54542.1 - 0.019 15.1 0.1 0.19 11.9 0.0 2.3 2 1 1 3 3 3 0 N-terminal helicase PWI domain PPR_3 PF13812.6 EKX54542.1 - 0.15 12.2 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Pentatricopeptide repeat domain NHL PF01436.21 EKX54543.1 - 3.7e-23 80.3 6.9 0.0026 17.7 0.3 6.5 6 0 0 6 6 6 6 NHL repeat Beta_helix PF13229.6 EKX54544.1 - 3.5e-11 43.2 0.1 5.7e-11 42.5 0.1 1.3 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 EKX54544.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Adeno_E3A PF05248.12 EKX54544.1 - 0.16 12.0 0.1 0.65 10.1 0.1 2.0 1 1 1 2 2 2 0 Adenovirus E3A CMD PF02627.20 EKX54545.1 - 2e-09 37.3 1.0 1.5e-08 34.5 0.0 2.5 3 0 0 3 3 3 1 Carboxymuconolactone decarboxylase family CMD PF02627.20 EKX54546.1 - 3.1e-09 36.8 1.0 2e-08 34.2 0.0 2.5 3 0 0 3 3 3 1 Carboxymuconolactone decarboxylase family LRR_6 PF13516.6 EKX54548.1 - 2.2e-08 33.5 8.5 0.0011 18.8 0.2 3.6 3 0 0 3 3 3 2 Leucine Rich repeat CALCOCO1 PF07888.11 EKX54548.1 - 0.0014 17.6 17.2 0.0019 17.2 17.2 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like HMMR_N PF15905.5 EKX54548.1 - 0.0071 15.9 11.1 0.038 13.5 8.2 2.2 1 1 1 2 2 2 1 Hyaluronan mediated motility receptor N-terminal Bacillus_HBL PF05791.11 EKX54548.1 - 0.0082 16.0 2.8 0.03 14.2 1.0 2.2 2 0 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) Snapin_Pallidin PF14712.6 EKX54548.1 - 0.0082 16.5 3.2 0.0082 16.5 3.2 2.6 2 1 1 3 3 2 1 Snapin/Pallidin ATG16 PF08614.11 EKX54548.1 - 0.01 16.1 10.6 0.01 16.1 10.6 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) TRAF_BIRC3_bd PF16673.5 EKX54548.1 - 0.031 14.1 5.4 0.17 11.7 0.0 3.0 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain PKcGMP_CC PF16808.5 EKX54548.1 - 0.033 14.0 1.1 0.033 14.0 1.1 2.0 2 0 0 2 2 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase LRR_4 PF12799.7 EKX54548.1 - 0.037 14.5 3.6 2 9.0 0.1 2.8 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX54548.1 - 0.047 13.5 4.0 1.1 9.0 0.1 2.6 2 1 0 2 2 2 0 Leucine rich repeat Csm1_N PF18504.1 EKX54548.1 - 0.054 13.8 11.8 0.063 13.6 0.8 3.0 2 1 1 3 3 3 0 Csm1 N-terminal domain Noelin-1 PF12308.8 EKX54548.1 - 0.07 13.1 4.8 0.084 12.9 0.8 2.5 1 1 1 2 2 2 0 Neurogenesis glycoprotein LRR_1 PF00560.33 EKX54548.1 - 0.22 12.2 3.6 3 8.7 0.2 2.9 2 1 0 2 2 2 0 Leucine Rich Repeat Lebercilin PF15619.6 EKX54548.1 - 0.23 11.1 16.6 0.25 11.0 7.7 2.8 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease bZIP_1 PF00170.21 EKX54548.1 - 0.23 11.6 10.9 0.3 11.2 4.8 2.6 2 0 0 2 2 2 0 bZIP transcription factor ADIP PF11559.8 EKX54548.1 - 0.31 11.1 15.8 0.13 12.3 3.2 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 EKX54548.1 - 0.39 10.7 16.5 6.7 6.7 16.5 2.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BRI3BP PF14965.6 EKX54548.1 - 0.56 9.7 1.7 2.2 7.7 0.1 2.2 2 0 0 2 2 2 0 Negative regulator of p53/TP53 DUF4407 PF14362.6 EKX54548.1 - 0.62 9.4 7.9 0.92 8.8 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DHR10 PF18595.1 EKX54548.1 - 0.78 9.8 17.1 5.2 7.2 4.9 2.7 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain TMF_DNA_bd PF12329.8 EKX54548.1 - 0.96 9.5 13.9 4.3 7.4 5.2 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Cep57_CLD_2 PF14197.6 EKX54548.1 - 1.4 9.0 15.4 4.9 7.3 1.7 3.5 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 FlaC_arch PF05377.11 EKX54548.1 - 1.9 8.9 11.2 4.9 7.6 3.3 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) XhlA PF10779.9 EKX54548.1 - 2.1 8.6 6.1 4.5 7.6 2.2 2.4 2 0 0 2 2 2 0 Haemolysin XhlA AAA_13 PF13166.6 EKX54548.1 - 4.3 5.9 8.9 1.2 7.7 2.4 2.0 1 1 0 1 1 1 0 AAA domain zf-C4H2 PF10146.9 EKX54548.1 - 5.5 7.2 9.2 5.1 7.4 7.9 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein DUF489 PF04356.12 EKX54548.1 - 6.1 6.8 10.1 16 5.4 0.2 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF489) Mod_r PF07200.13 EKX54548.1 - 6.9 6.8 15.4 4.9 7.3 5.2 3.0 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein JIP_LZII PF16471.5 EKX54548.1 - 8.5 6.6 13.2 2 8.6 7.0 2.7 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF4201 PF13870.6 EKX54548.1 - 9.7 5.9 15.2 2.2e+03 -1.8 15.3 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Arm PF00514.23 EKX54549.1 - 0.0033 17.4 7.1 1.6 8.8 0.1 4.2 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat TPR_16 PF13432.6 EKX54551.1 - 8.5e-05 23.1 0.0 0.0023 18.5 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX54551.1 - 0.00068 19.8 0.0 0.027 14.8 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX54551.1 - 0.0032 17.9 0.1 0.42 11.2 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX54551.1 - 0.032 14.3 2.4 17 5.8 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EKX54551.1 - 0.06 13.2 2.4 22 5.1 0.0 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Herpes_UL31 PF02718.14 EKX54551.1 - 0.11 11.5 0.2 0.19 10.7 0.2 1.3 1 0 0 1 1 1 0 Herpesvirus UL31-like protein TPR_11 PF13414.6 EKX54551.1 - 0.18 11.5 0.5 2.1 8.1 0.0 3.1 4 1 1 5 5 5 0 TPR repeat TPR_14 PF13428.6 EKX54551.1 - 2.1 9.4 5.3 74 4.6 0.0 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat LIM PF00412.22 EKX54552.1 - 0.0023 18.1 0.6 0.0044 17.2 0.6 1.4 1 0 0 1 1 1 1 LIM domain HECA PF15353.6 EKX54552.1 - 0.0051 17.0 0.4 0.94 9.8 0.1 2.2 1 1 0 2 2 2 2 Headcase protein family homologue DUF2175 PF09943.9 EKX54552.1 - 0.014 15.7 0.2 0.026 14.8 0.1 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) zf-PARP PF00645.18 EKX54552.1 - 0.022 15.6 0.1 0.047 14.5 0.0 1.5 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Zf_RING PF16744.5 EKX54552.1 - 0.084 13.0 0.2 0.18 12.0 0.0 1.6 2 0 0 2 2 2 0 KIAA1045 RING finger zf-RING_2 PF13639.6 EKX54552.1 - 0.12 12.7 0.2 0.56 10.6 0.0 2.0 2 0 0 2 2 2 0 Ring finger domain C1_1 PF00130.22 EKX54552.1 - 0.34 10.8 2.3 2.8 7.9 0.4 2.7 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FAD_binding_2 PF00890.24 EKX54553.1 - 4.3e-123 411.5 3.3 6e-123 411.0 3.3 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EKX54553.1 - 3e-44 150.1 0.0 4.5e-44 149.5 0.0 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 EKX54553.1 - 9.9e-06 25.0 2.1 0.0023 17.2 0.4 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EKX54553.1 - 0.00016 20.9 1.1 0.04 13.0 2.3 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 EKX54553.1 - 0.00028 20.2 0.3 0.05 12.8 0.0 2.4 2 0 0 2 2 2 2 Thi4 family DAO PF01266.24 EKX54553.1 - 0.04 13.5 0.8 0.1 12.1 0.4 2.0 2 1 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EKX54553.1 - 0.045 12.4 2.7 0.12 11.1 0.8 2.5 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_3 PF01494.19 EKX54553.1 - 0.05 12.9 0.2 0.08 12.2 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EKX54553.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EKX54553.1 - 0.25 10.6 0.4 3.4 6.8 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase PWWP PF00855.17 EKX54554.1 - 2.5e-06 27.8 2.2 2.5e-06 27.8 2.2 3.7 2 1 1 3 3 3 1 PWWP domain RRM_1 PF00076.22 EKX54554.1 - 6.6e-06 25.9 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_1 PF00013.29 EKX54554.1 - 7.4e-06 25.7 0.3 2.2e-05 24.2 0.3 1.9 1 0 0 1 1 1 1 KH domain Ank_4 PF13637.6 EKX54556.1 - 1.2e-09 38.5 0.0 5e-08 33.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX54556.1 - 2.8e-09 37.1 0.0 7e-05 23.0 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX54556.1 - 2.4e-08 34.4 0.0 5.1e-07 30.2 0.0 2.6 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX54556.1 - 1.4e-06 28.2 0.1 0.072 13.7 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EKX54556.1 - 4.9e-06 26.7 0.0 0.043 14.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat DUF3970 PF13113.6 EKX54556.1 - 0.047 13.9 1.0 0.047 13.9 1.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3970) BK_channel_a PF03493.18 EKX54557.1 - 2.9e-18 65.8 0.3 1.1e-17 64.0 0.2 2.0 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 EKX54557.1 - 7.5e-11 41.8 0.9 7.5e-11 41.8 0.9 2.8 3 0 0 3 3 3 1 Ion channel Ion_trans PF00520.31 EKX54557.1 - 1.9e-10 40.4 14.0 3.2e-10 39.7 14.0 1.3 1 0 0 1 1 1 1 Ion transport protein TrkA_N PF02254.18 EKX54557.1 - 1.3e-08 35.0 1.3 1.9e-07 31.3 0.1 2.9 3 1 0 3 3 3 1 TrkA-N domain DUF4033 PF13225.6 EKX54557.1 - 0.035 14.1 0.2 0.096 12.7 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4033) DNA_pol_delta_4 PF04081.13 EKX54558.1 - 3.3e-18 66.3 2.0 1.6e-17 64.1 2.0 2.1 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 FYVE PF01363.21 EKX54559.1 - 5.9e-17 61.6 11.2 6.7e-17 61.4 11.2 1.0 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 EKX54559.1 - 0.014 15.6 8.8 0.016 15.4 8.8 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger RabGAP-TBC PF00566.18 EKX54560.1 - 2.7e-40 138.3 0.0 3.8e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain LRR_6 PF13516.6 EKX54561.1 - 6.3e-21 72.6 17.4 0.0012 18.7 0.5 8.1 8 0 0 8 8 8 7 Leucine Rich repeat LRR_1 PF00560.33 EKX54561.1 - 2.5e-06 27.3 2.6 16 6.5 0.0 6.3 6 0 0 6 6 6 3 Leucine Rich Repeat PPR_2 PF13041.6 EKX54562.1 - 7e-07 29.3 0.9 0.036 14.3 0.0 2.9 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.6 EKX54562.1 - 0.0012 18.9 0.0 0.1 12.7 0.0 2.5 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR PF01535.20 EKX54562.1 - 0.01 16.0 2.5 2.7 8.4 0.4 3.1 2 0 0 2 2 2 0 PPR repeat SPT16 PF08644.11 EKX54562.1 - 1.5 9.0 6.2 0.16 12.2 1.6 1.6 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) DUF501 PF04417.12 EKX54562.1 - 2 8.2 6.9 1.3 8.8 2.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF501) Spt20 PF12090.8 EKX54563.1 - 5.9e-13 49.0 0.0 1.7e-09 37.7 0.0 2.4 1 1 1 2 2 2 2 Spt20 family MORN PF02493.20 EKX54565.1 - 1.3e-15 56.2 19.7 1.3e-05 24.8 1.6 4.2 4 0 0 4 4 4 4 MORN repeat YkuD PF03734.14 EKX54565.1 - 0.057 13.8 0.1 0.062 13.7 0.1 1.1 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain DUF1515 PF07439.11 EKX54566.1 - 0.85 9.7 4.0 0.85 9.7 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) NUDIX-like PF09296.11 EKX54566.1 - 1.6 9.4 10.9 2.5 8.8 1.4 3.8 3 0 0 3 3 3 0 NADH pyrophosphatase-like rudimentary NUDIX domain EF-hand_1 PF00036.32 EKX54568.1 - 2.6e-06 26.6 2.4 0.053 13.1 0.2 2.9 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX54568.1 - 9.9e-06 25.9 0.9 0.023 15.1 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX54568.1 - 1.3e-05 24.8 1.5 0.1 12.6 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EKX54568.1 - 9.3e-05 21.8 0.3 0.017 14.6 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EKX54568.1 - 0.0073 16.1 0.5 0.86 9.5 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EKX54568.1 - 0.1 12.9 3.0 0.81 10.0 3.0 2.3 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region 2TM PF13239.6 EKX54569.1 - 0.0025 18.1 0.9 0.0065 16.8 0.9 1.7 1 0 0 1 1 1 1 2TM domain SK_channel PF03530.14 EKX54569.1 - 0.0068 16.4 2.3 0.0068 16.4 2.3 3.2 2 2 1 3 3 3 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.16 EKX54569.1 - 0.46 10.5 10.2 0.12 12.4 3.5 2.5 2 0 0 2 2 2 0 Ion channel 2-oxoacid_dh PF00198.23 EKX54570.1 - 7.3e-84 280.8 0.0 1e-83 280.4 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EKX54570.1 - 1.5e-33 114.5 2.5 5.6e-16 58.1 0.3 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme E3_binding PF02817.17 EKX54570.1 - 5.3e-14 52.3 0.1 1.1e-13 51.2 0.1 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EKX54570.1 - 1.2e-05 25.1 0.0 0.051 13.4 0.0 2.9 3 0 0 3 3 3 2 Biotin-lipoyl like Pox_RNA_pol PF03293.14 EKX54570.1 - 0.11 12.2 0.0 18 5.0 0.0 2.5 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit HlyD_2 PF12700.7 EKX54570.1 - 0.14 10.9 0.0 1.4 7.6 0.0 2.1 2 0 0 2 2 2 0 HlyD family secretion protein PDZ PF00595.24 EKX54573.1 - 3.2e-05 24.2 0.4 8.4e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EKX54573.1 - 0.049 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 PDZ domain IGR PF09597.10 EKX54574.1 - 0.0082 16.2 0.1 0.61 10.2 0.0 2.4 2 0 0 2 2 2 2 IGR protein motif CHAT PF12770.7 EKX54575.1 - 0.061 12.7 0.3 0.1 12.0 0.3 1.3 1 0 0 1 1 1 0 CHAT domain Acyl-CoA_dh_N PF02771.16 EKX54577.1 - 0.081 13.6 0.0 0.097 13.3 0.0 1.1 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Exo_endo_phos PF03372.23 EKX54578.1 - 9.7e-08 31.8 0.5 5e-07 29.5 0.5 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_L31e PF01198.19 EKX54579.1 - 3.9e-42 142.4 1.5 5e-42 142.0 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e DUF2313 PF10076.9 EKX54579.1 - 0.11 12.3 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2313) Ephrin_rec_like PF07699.13 EKX54580.1 - 2.7e-28 97.5 45.6 8.4e-11 41.5 3.5 5.8 4 2 2 6 6 6 5 Putative ephrin-receptor like TNFR_c6 PF00020.18 EKX54580.1 - 0.0019 18.6 34.5 0.68 10.4 0.6 7.3 3 3 3 7 7 7 4 TNFR/NGFR cysteine-rich region Feld-I_B PF09252.10 EKX54580.1 - 0.044 13.7 2.5 2.1 8.4 0.0 2.7 3 0 0 3 3 3 0 Allergen Fel d I-B chain Kinesin PF00225.23 EKX54582.1 - 4.9e-79 265.7 0.0 5.5e-79 265.5 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX54582.1 - 3.7e-13 49.7 0.0 1.1e-12 48.1 0.0 1.9 1 1 0 1 1 1 1 Microtubule binding AdoHcyase PF05221.17 EKX54582.1 - 0.084 12.0 0.1 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase PEARLI-4 PF05278.12 EKX54583.1 - 0.12 12.0 4.8 0.17 11.4 4.8 1.4 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) BRE1 PF08647.11 EKX54583.1 - 0.32 11.1 7.8 0.1 12.7 3.9 2.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase ERM PF00769.19 EKX54583.1 - 0.47 10.2 15.4 0.65 9.8 15.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Plasmid_RAQPRD PF09686.10 EKX54583.1 - 0.53 10.5 5.7 1.2 9.4 4.8 2.0 1 1 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DivIC PF04977.15 EKX54583.1 - 1.8 8.4 7.1 14 5.5 0.0 3.0 2 1 0 3 3 3 0 Septum formation initiator Efg1 PF10153.9 EKX54583.1 - 1.9 8.9 7.4 3.5 8.0 7.4 1.5 1 1 0 1 1 1 0 rRNA-processing protein Efg1 Cep57_CLD_2 PF14197.6 EKX54583.1 - 2 8.6 18.7 0.14 12.2 9.4 2.7 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 APG6_N PF17675.1 EKX54583.1 - 8.4 6.9 13.0 25 5.4 13.0 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF1242 PF06842.12 EKX54584.1 - 6.8e-20 70.6 1.4 9.1e-20 70.2 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Jag_N PF14804.6 EKX54584.1 - 0.12 12.7 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 Jag N-terminus DXP_synthase_N PF13292.6 EKX54585.1 - 2.8e-105 351.4 0.0 4.4e-105 350.8 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 EKX54585.1 - 7.6e-41 139.7 0.0 1.4e-40 138.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EKX54585.1 - 1.2e-22 80.1 0.0 2.7e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transketolase_N PF00456.21 EKX54585.1 - 2.5e-05 23.4 0.0 0.32 9.9 0.2 3.1 3 1 0 3 3 3 2 Transketolase, thiamine diphosphate binding domain TPP_enzyme_C PF02775.21 EKX54585.1 - 0.00027 20.7 0.0 0.00066 19.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 EKX54585.1 - 0.00082 18.4 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component IGPS PF00218.21 EKX54586.1 - 0.004 16.4 0.0 0.0065 15.7 0.0 1.4 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase NMO PF03060.15 EKX54586.1 - 0.0097 15.3 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Radial_spoke PF04712.12 EKX54588.1 - 6.8e-75 252.9 0.0 7.7e-74 249.4 0.0 1.9 1 1 0 1 1 1 1 Radial spokehead-like protein Arm PF00514.23 EKX54589.1 - 7.9e-09 35.3 6.9 8.1e-05 22.5 0.0 3.6 3 1 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EKX54589.1 - 0.00012 22.4 1.7 0.0063 16.9 0.6 3.0 1 1 1 2 2 2 1 HEAT repeats IFRD PF05004.13 EKX54589.1 - 0.034 13.3 1.8 0.063 12.4 1.8 1.5 1 1 0 1 1 1 0 Interferon-related developmental regulator (IFRD) RasGEF_N_2 PF14663.6 EKX54589.1 - 0.093 13.1 0.4 11 6.5 0.1 2.9 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain HEAT PF02985.22 EKX54589.1 - 0.12 12.7 3.3 17 6.0 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat Atx10homo_assoc PF09759.9 EKX54589.1 - 0.13 12.3 0.1 2.7 8.1 0.0 2.4 2 1 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 EKX54589.1 - 0.55 10.8 5.0 12 6.6 0.3 3.3 2 2 1 3 3 3 0 HEAT-like repeat zinc_ribbon_2 PF13240.6 EKX54590.1 - 4.8e-07 29.3 3.4 1.1e-06 28.2 3.4 1.6 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 EKX54590.1 - 1.2e-05 25.2 3.5 2e-05 24.5 3.5 1.4 1 0 0 1 1 1 1 Double zinc ribbon zf-NADH-PPase PF09297.11 EKX54590.1 - 0.00031 20.3 1.8 0.054 13.2 0.2 2.5 2 0 0 2 2 2 2 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.6 EKX54590.1 - 0.00047 19.5 2.2 0.00047 19.5 2.2 1.9 2 0 0 2 2 2 1 zinc-ribbon domain Nudix_N_2 PF14803.6 EKX54590.1 - 0.0017 18.2 3.8 0.054 13.4 0.3 2.5 2 0 0 2 2 2 1 Nudix N-terminal DUF2076 PF09849.9 EKX54590.1 - 0.0063 16.6 8.1 0.0063 16.6 8.1 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) zf_UBZ PF18439.1 EKX54590.1 - 0.015 14.9 1.3 2.1 8.0 0.1 2.3 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger UPF0547 PF10571.9 EKX54590.1 - 0.037 14.1 2.6 0.18 11.9 2.7 2.2 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 DHHC PF01529.20 EKX54590.1 - 0.098 12.8 0.3 0.13 12.3 0.3 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Zn_ribbon_recom PF13408.6 EKX54590.1 - 0.11 13.1 0.4 22 5.7 0.0 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zinc_ribbon_15 PF17032.5 EKX54590.1 - 0.13 13.1 2.0 0.13 13.1 2.0 1.6 2 0 0 2 2 2 0 zinc-ribbon family zf-C3HC4_3 PF13920.6 EKX54590.1 - 0.14 12.1 0.6 0.14 12.1 0.6 1.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HypA PF01155.19 EKX54590.1 - 0.31 11.1 0.6 0.49 10.4 0.6 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_C2H2_13 PF18508.1 EKX54590.1 - 0.99 9.0 3.3 0.5 10.0 0.3 1.9 1 1 1 2 2 2 0 Zinc finger domain NOB1_Zn_bind PF08772.11 EKX54590.1 - 3 8.1 5.2 12 6.2 5.2 1.9 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like COX1 PF00115.20 EKX54591.1 - 0.0006 18.8 0.1 0.0009 18.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I MtN3_slv PF03083.16 EKX54591.1 - 0.088 12.9 0.5 0.26 11.4 0.5 1.8 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange TRIQK PF15168.6 EKX54591.1 - 0.24 11.3 0.5 0.87 9.5 0.5 1.9 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family RabGAP-TBC PF00566.18 EKX54592.1 - 7e-43 146.8 1.1 5.7e-42 143.8 1.1 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain GTP_EFTU PF00009.27 EKX54593.1 - 1.8e-47 161.4 0.0 2.7e-47 160.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EKX54593.1 - 5.8e-43 145.7 0.2 1.7e-42 144.2 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EKX54593.1 - 3.3e-15 56.2 0.9 8e-15 55.0 0.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EKX54593.1 - 0.00027 21.0 0.1 0.0067 16.5 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EKX54593.1 - 0.0036 17.2 0.1 0.012 15.5 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Lactamase_B_2 PF12706.7 EKX54593.1 - 0.077 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain SRPRB PF09439.10 EKX54593.1 - 0.13 11.7 0.1 0.83 9.1 0.1 2.0 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FoP_duplication PF13865.6 EKX54594.1 - 2.7e-06 27.8 10.9 2.7e-06 27.8 10.9 2.5 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Nop14 PF04147.12 EKX54594.1 - 0.086 11.0 7.2 0.084 11.1 7.2 1.0 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 EKX54594.1 - 3.5 6.3 4.2 3.4 6.3 4.2 1.0 1 0 0 1 1 1 0 Presenilin Glyco_transf_41 PF13844.6 EKX54595.1 - 9.1e-18 63.9 0.0 7.6e-15 54.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_2 PF07719.17 EKX54595.1 - 6e-17 60.3 18.3 0.0013 18.7 0.3 9.4 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 EKX54595.1 - 1.2e-15 56.5 7.6 0.0015 18.2 0.2 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 EKX54595.1 - 3.4e-12 45.8 6.6 0.028 14.1 0.2 5.7 2 1 3 5 5 5 5 TPR repeat TPR_8 PF13181.6 EKX54595.1 - 6.2e-12 44.7 7.6 0.048 13.9 0.0 7.2 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EKX54595.1 - 4.1e-11 42.7 11.8 0.0041 17.8 0.1 6.7 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 EKX54595.1 - 1.4e-09 38.3 6.5 0.00056 20.4 0.0 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX54595.1 - 1.7e-09 38.2 19.1 0.00053 20.6 2.8 6.0 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 EKX54595.1 - 3.4e-09 36.1 2.1 0.29 11.2 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX54595.1 - 1.8e-08 34.6 18.4 0.0027 18.0 0.7 5.5 2 1 5 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 EKX54595.1 - 1.1e-06 28.3 12.9 0.019 14.8 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EKX54595.1 - 1.3e-06 28.4 6.7 0.32 11.5 0.0 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX54595.1 - 2.5e-05 24.4 8.4 0.0083 16.3 0.6 4.7 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 EKX54595.1 - 5e-05 23.5 4.8 0.065 13.9 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX54595.1 - 7.2e-05 23.2 8.5 0.11 13.2 0.1 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EKX54595.1 - 0.00014 21.9 11.3 0.00075 19.6 0.3 5.0 4 1 2 6 6 6 1 Tetratricopeptide repeat DUF3856 PF12968.7 EKX54595.1 - 0.00062 19.8 1.6 0.72 9.9 0.1 2.7 2 0 0 2 2 2 2 Domain of Unknown Function (DUF3856) ArsR PF09824.9 EKX54595.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 ArsR transcriptional regulator ChAPs PF09295.10 EKX54595.1 - 0.16 10.9 0.1 0.25 10.3 0.1 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_5 PF12688.7 EKX54595.1 - 0.16 12.2 0.8 1.4 9.1 0.0 2.7 3 0 0 3 3 3 0 Tetratrico peptide repeat PAE PF03283.13 EKX54596.1 - 2e-54 185.1 5.7 1.2e-38 133.2 1.3 2.1 1 1 1 2 2 2 2 Pectinacetylesterase P22_AR_C PF10548.9 EKX54596.1 - 2.4 8.4 4.8 4.3 7.6 0.8 2.3 2 0 0 2 2 2 0 P22AR C-terminal domain DUF393 PF04134.12 EKX54597.1 - 1.2e-24 87.8 0.0 1.5e-24 87.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF393 CDC48_N PF02359.18 EKX54598.1 - 0.0098 16.1 0.0 0.22 11.7 0.0 2.8 2 1 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain PDZ PF00595.24 EKX54598.1 - 0.034 14.5 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 PDZ domain PDZ_2 PF13180.6 EKX54598.1 - 0.067 13.5 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 EKX54598.1 - 0.073 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 PDZ domain CC2-LZ PF16516.5 EKX54598.1 - 0.59 10.5 7.4 0.6 10.5 2.4 3.3 3 0 0 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Spc42p PF11544.8 EKX54598.1 - 0.69 9.9 10.8 0.15 12.1 0.9 3.4 2 1 1 3 3 3 0 Spindle pole body component Spc42p ADIP PF11559.8 EKX54598.1 - 3.5 7.7 12.4 0.21 11.7 5.7 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding COX5B PF01215.19 EKX54599.1 - 2.8e-23 82.0 0.0 3.6e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Pribosyltran_N PF13793.6 EKX54600.1 - 6.9e-38 129.2 1.2 3.3e-37 127.0 0.1 2.2 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EKX54600.1 - 4.4e-20 72.5 0.4 9.8e-20 71.4 0.4 1.5 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EKX54600.1 - 1.1e-14 54.3 0.2 2.1e-14 53.3 0.2 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EKX54600.1 - 0.027 13.9 0.1 0.038 13.4 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Sec7 PF01369.20 EKX54601.1 - 1.1e-25 90.4 0.0 5e-25 88.2 0.0 1.8 2 0 0 2 2 2 1 Sec7 domain F-box-like PF12937.7 EKX54601.1 - 0.017 15.0 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 F-box-like LD_cluster2 PF18163.1 EKX54601.1 - 0.12 11.8 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 SLOG cluster2 DUF4298 PF14131.6 EKX54602.1 - 0.027 14.4 0.1 0.027 14.4 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) Csm1_N PF18504.1 EKX54602.1 - 0.13 12.6 12.8 0.42 11.0 3.1 4.0 3 0 0 3 3 3 0 Csm1 N-terminal domain DUF3450 PF11932.8 EKX54602.1 - 0.26 10.6 32.3 0.038 13.3 6.1 4.6 4 1 0 4 4 4 0 Protein of unknown function (DUF3450) CinA_KH PF18146.1 EKX54602.1 - 0.57 10.4 4.9 34 4.7 0.3 4.3 3 1 0 3 3 3 0 Damage-inducible protein CinA KH domain DASH_Spc34 PF08657.10 EKX54602.1 - 1.3 8.7 6.7 7.4 6.3 1.1 2.6 2 0 0 2 2 2 0 DASH complex subunit Spc34 DUF4239 PF14023.6 EKX54602.1 - 1.9 8.2 7.8 0.89 9.2 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4239) Med15_fungi PF05397.12 EKX54602.1 - 2.9 8.2 6.8 0.61 10.4 0.7 2.9 3 0 0 3 3 3 0 Mediator complex subunit 15 DivIC PF04977.15 EKX54602.1 - 5.1 6.9 15.8 7.3 6.4 3.9 4.4 3 1 0 3 3 3 0 Septum formation initiator Prefoldin_2 PF01920.20 EKX54602.1 - 6.2 6.8 22.4 4.3 7.3 0.0 4.5 5 0 0 5 5 5 0 Prefoldin subunit ZapB PF06005.12 EKX54602.1 - 7.7 7.0 9.6 21 5.6 1.7 3.2 2 0 0 2 2 2 0 Cell division protein ZapB LRR_6 PF13516.6 EKX54603.1 - 3.5e-14 51.6 13.8 0.11 12.7 0.3 8.3 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.7 EKX54603.1 - 9e-05 22.8 5.8 0.041 14.3 0.6 4.1 3 2 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX54603.1 - 0.22 12.2 6.5 11 7.1 0.1 5.7 8 0 0 8 8 8 0 Leucine Rich Repeat Autoind_bind PF03472.15 EKX54604.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Autoinducer binding domain Beta_helix PF13229.6 EKX54605.1 - 1.1e-08 35.0 0.2 2.4e-05 24.2 0.1 2.0 1 1 1 2 2 2 2 Right handed beta helix region FKBP_N_2 PF18023.1 EKX54605.1 - 0.14 12.3 0.2 0.62 10.2 0.0 2.1 2 0 0 2 2 2 0 BDBT FKBP like N-terminal DUF2457 PF10446.9 EKX54606.1 - 0.32 10.1 10.4 0.37 9.9 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Retinal PF15449.6 EKX54606.1 - 1.6 6.4 13.0 1.8 6.3 13.0 1.1 1 0 0 1 1 1 0 Retinal protein LRR_4 PF12799.7 EKX54607.1 - 3.3e-13 49.6 1.3 5.9e-06 26.5 0.0 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX54607.1 - 1.3e-11 44.3 0.0 1.6e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 EKX54607.1 - 3.6e-08 33.1 5.8 4.8e-05 23.0 0.4 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 EKX54607.1 - 0.00072 19.8 0.4 13 6.8 0.0 4.4 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 EKX54607.1 - 0.051 13.6 4.6 13 6.1 0.1 4.3 5 0 0 5 5 5 0 Leucine Rich repeat AtpR PF12966.7 EKX54608.1 - 0.0013 19.2 0.2 0.0024 18.3 0.2 1.4 1 0 0 1 1 1 1 N-ATPase, AtpR subunit ATP-synt_I PF03899.15 EKX54608.1 - 0.06 13.7 0.7 0.14 12.5 0.7 1.6 1 0 0 1 1 1 0 ATP synthase I chain MMR_HSR1 PF01926.23 EKX54609.1 - 0.00086 19.4 0.1 0.011 15.8 0.1 3.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EKX54609.1 - 0.0031 17.4 3.2 0.0062 16.5 0.6 2.9 2 1 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EKX54609.1 - 0.0034 17.1 1.4 0.036 13.8 0.2 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_7 PF12775.7 EKX54609.1 - 0.024 14.2 1.0 0.086 12.4 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 EKX54609.1 - 0.079 13.5 0.0 0.079 13.5 0.0 4.5 4 2 0 4 4 4 0 ABC transporter AAA_23 PF13476.6 EKX54609.1 - 0.49 10.9 0.0 0.49 10.9 0.0 8.5 3 2 2 5 5 5 0 AAA domain AAA_21 PF13304.6 EKX54609.1 - 2.4 7.9 0.0 2.4 7.9 0.0 4.2 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Peptidase_M22 PF00814.25 EKX54611.1 - 0.063 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Glycoprotease family StbA PF06406.11 EKX54611.1 - 0.093 11.9 0.0 11 5.2 0.0 2.2 2 0 0 2 2 2 0 StbA protein Rhomboid PF01694.22 EKX54612.1 - 5.8e-13 49.1 6.7 3.9e-11 43.2 5.3 2.5 2 1 0 2 2 2 2 Rhomboid family SAM_2 PF07647.17 EKX54612.1 - 4.5e-12 45.9 0.0 1.1e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EKX54612.1 - 7.1e-10 39.2 0.0 1.7e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 EKX54612.1 - 0.00062 19.7 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain DUF1751 PF08551.10 EKX54612.1 - 0.039 14.5 0.0 0.85 10.2 0.0 2.6 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) C2 PF00168.30 EKX54614.1 - 1.2e-18 67.3 0.0 5.2e-18 65.2 0.0 2.1 1 0 0 1 1 1 1 C2 domain DUF4215 PF13948.6 EKX54614.1 - 1.2e-06 28.8 5.3 3.9e-06 27.2 5.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4215) EF-hand_8 PF13833.6 EKX54614.1 - 0.02 14.7 0.0 0.06 13.2 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 EKX54614.1 - 0.026 14.0 0.1 0.094 12.3 0.1 2.0 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 EKX54614.1 - 0.065 12.8 0.2 0.23 11.0 0.2 1.9 1 0 0 1 1 1 0 EF hand Fibrillarin PF01269.17 EKX54615.1 - 1.4e-108 361.2 0.1 1.7e-108 361.0 0.1 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EKX54615.1 - 1.8e-05 24.5 0.0 2.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 EKX54615.1 - 0.04 13.7 0.1 0.064 13.0 0.1 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 EKX54615.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Peptidase_M24 PF00557.24 EKX54617.1 - 6.2e-50 169.8 0.1 7.9e-50 169.4 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EKX54617.1 - 5.5e-26 90.7 0.0 1.1e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.7 EKX54617.1 - 0.19 11.7 0.3 0.42 10.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3793) DUF3318 PF11780.8 EKX54618.1 - 0.028 14.3 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) Acyl-CoA_dh_1 PF00441.24 EKX54620.1 - 3.8e-43 147.3 1.9 5.3e-43 146.8 1.9 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EKX54620.1 - 3.2e-27 95.4 0.3 7.4e-27 94.3 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EKX54620.1 - 2e-25 88.8 0.1 4.6e-25 87.7 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EKX54620.1 - 6e-19 68.6 0.0 9.4e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Ank_2 PF12796.7 EKX54622.1 - 0.0001 22.8 0.1 0.00038 21.0 0.1 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX54622.1 - 0.00023 21.4 0.1 0.43 11.3 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EKX54622.1 - 0.017 15.5 0.3 0.061 13.8 0.2 2.1 2 0 0 2 2 2 0 Ankyrin repeat ABC2_membrane PF01061.24 EKX54623.1 - 6.9e-12 45.2 1.2 9.5e-12 44.8 1.2 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 EKX54623.1 - 3.5e-05 23.1 1.4 5.1e-05 22.5 1.4 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 EKX54624.1 - 9.4e-11 42.4 0.6 6.2e-09 36.5 0.2 2.2 2 0 0 2 2 2 1 ABC transporter Rad17 PF03215.15 EKX54624.1 - 0.00019 21.4 0.0 0.00029 20.8 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 EKX54624.1 - 0.00064 19.7 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 EKX54624.1 - 0.0051 16.7 0.5 0.16 11.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EKX54624.1 - 0.0075 16.5 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EKX54624.1 - 0.0078 16.6 0.9 0.01 16.3 0.9 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EKX54624.1 - 0.011 16.2 0.4 0.021 15.3 0.4 1.4 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EKX54624.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_35 PF14516.6 EKX54624.1 - 0.12 11.2 0.1 0.17 10.6 0.1 1.2 1 0 0 1 1 1 0 AAA-like domain NACHT PF05729.12 EKX54624.1 - 0.13 12.2 0.2 0.21 11.5 0.2 1.3 1 0 0 1 1 1 0 NACHT domain RRM_1 PF00076.22 EKX54625.1 - 2.7e-07 30.3 0.1 7.9e-07 28.8 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hydrolase_4 PF12146.8 EKX54626.1 - 0.095 11.9 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PMSR PF01625.21 EKX54627.1 - 2.3e-27 96.0 0.3 2.7e-27 95.8 0.3 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase FKBP_C PF00254.28 EKX54628.1 - 2e-17 63.2 0.0 2e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Cutinase PF01083.22 EKX54628.1 - 0.22 11.5 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 Cutinase TRAP_alpha PF03896.16 EKX54629.1 - 0.0018 17.6 4.1 0.0029 16.9 4.1 1.3 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Herpes_UL87 PF03043.14 EKX54629.1 - 0.16 10.4 1.9 0.4 9.1 0.6 1.6 1 1 0 2 2 2 0 Herpesvirus UL87 family E7 PF00527.18 EKX54629.1 - 0.21 11.8 3.1 0.2 11.9 1.0 2.1 2 0 0 2 2 2 0 E7 protein, Early protein FliJ PF02050.16 EKX54629.1 - 0.45 10.7 9.9 0.58 10.4 8.1 2.1 1 1 0 1 1 1 0 Flagellar FliJ protein SAM_1 PF00536.30 EKX54630.1 - 6.2e-07 29.8 0.0 1.3e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EKX54630.1 - 0.00036 20.6 0.0 0.00091 19.3 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF3173 PF11372.8 EKX54630.1 - 0.068 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3173) Guanylate_cyc PF00211.20 EKX54631.1 - 3.5e-19 69.1 0.0 3.7e-19 69.1 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Glu_cyclase_2 PF05096.12 EKX54632.1 - 3.5e-68 229.8 0.6 7.1e-68 228.7 0.6 1.4 1 1 0 1 1 1 1 Glutamine cyclotransferase FUSC-like PF12805.7 EKX54633.1 - 1.7 7.7 4.2 5.1 6.1 2.4 2.2 1 1 1 2 2 2 0 FUSC-like inner membrane protein yccS Mannitol_dh PF01232.23 EKX54633.1 - 1.9 8.6 9.9 0.32 11.1 2.9 2.4 2 1 0 2 2 2 0 Mannitol dehydrogenase Rossmann domain TOM20_plant PF06552.12 EKX54634.1 - 1.8e-27 96.3 0.0 2.3e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_17 PF13431.6 EKX54634.1 - 7.9e-08 32.2 0.7 0.16 12.4 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX54634.1 - 0.00031 20.6 0.1 0.065 13.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX54634.1 - 0.0048 16.7 0.0 0.063 13.1 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX54634.1 - 0.012 16.3 0.1 6.2 7.9 0.1 3.8 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EKX54634.1 - 0.014 15.1 0.1 3.9 7.2 0.0 3.4 3 0 0 3 3 3 0 TPR repeat Fis1_TPR_C PF14853.6 EKX54634.1 - 0.038 14.1 0.2 0.11 12.5 0.2 1.9 1 1 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 EKX54634.1 - 0.045 14.0 0.0 0.52 10.7 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat AAA_assoc_C PF09821.9 EKX54635.1 - 0.92 10.1 6.7 0.59 10.7 0.2 3.3 3 0 0 3 3 3 0 C-terminal AAA-associated domain PSK_trans_fac PF07704.11 EKX54635.1 - 1.1 10.1 4.7 23 5.8 0.5 3.6 2 1 1 3 3 3 0 Rv0623-like transcription factor Hrs_helical PF12210.8 EKX54635.1 - 2.7 8.6 17.4 0.68 10.5 1.7 4.1 3 1 1 4 4 4 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Pro_CA PF00484.19 EKX54635.1 - 4.5 7.5 9.8 0.21 11.9 1.0 2.9 3 0 0 3 3 3 0 Carbonic anhydrase ABC_tran_CTD PF16326.5 EKX54635.1 - 5.9 7.2 24.5 11 6.4 2.3 4.7 2 1 2 4 4 4 0 ABC transporter C-terminal domain DnaJ PF00226.31 EKX54636.1 - 2.8e-08 33.8 0.0 6.9e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain AAA_18 PF13238.6 EKX54636.1 - 0.029 14.9 0.5 0.14 12.7 0.1 2.4 1 1 1 2 2 2 0 AAA domain DASH_Dad2 PF08654.10 EKX54636.1 - 1.7 9.1 6.0 0.89 10.0 2.8 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad2 PAS_9 PF13426.7 EKX54638.1 - 0.011 16.0 0.0 0.083 13.1 0.0 2.4 2 0 0 2 2 2 0 PAS domain PAS_9 PF13426.7 EKX54639.1 - 0.01 16.1 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 PAS domain PAS_9 PF13426.7 EKX54641.1 - 0.0092 16.2 0.0 0.024 14.9 0.0 1.7 2 0 0 2 2 2 1 PAS domain Pantoate_transf PF02548.15 EKX54642.1 - 1.8e-100 335.6 0.3 2.2e-100 335.4 0.3 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase Asp_Glu_race PF01177.22 EKX54642.1 - 0.016 15.1 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase PEP_mutase PF13714.6 EKX54642.1 - 0.022 14.2 0.2 0.27 10.7 0.0 2.1 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase BcrAD_BadFG PF01869.20 EKX54643.1 - 3.1e-33 115.4 4.2 3.7e-33 115.1 4.2 1.0 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family FGGY_N PF00370.21 EKX54643.1 - 0.0046 16.6 0.2 0.0082 15.7 0.2 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain ROK PF00480.20 EKX54643.1 - 0.028 13.9 0.9 0.075 12.5 0.2 2.0 2 0 0 2 2 2 0 ROK family MFS_1 PF07690.16 EKX54645.1 - 4.1e-24 85.2 14.3 3.3e-23 82.2 11.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 EKX54645.1 - 0.00039 19.3 5.6 0.00092 18.1 5.6 1.6 1 0 0 1 1 1 1 LacY proton/sugar symporter SET PF00856.28 EKX54646.1 - 7.2e-07 29.7 0.0 1.4e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 EKX54646.1 - 7e-05 23.5 0.3 0.00015 22.5 0.3 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Aminotran_1_2 PF00155.21 EKX54648.1 - 2.4e-42 145.4 0.0 3.2e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 EKX54648.1 - 0.0011 18.0 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Allinase Collagen PF01391.18 EKX54649.1 - 4.6e-15 55.1 62.0 4.4e-09 36.0 27.3 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Sigma70_ner PF04546.13 EKX54649.1 - 0.00018 21.5 3.5 0.00023 21.1 3.5 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region Tho2 PF11262.8 EKX54649.1 - 0.054 12.7 0.2 0.059 12.6 0.2 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Nup54 PF13874.6 EKX54649.1 - 0.084 13.0 2.5 0.12 12.4 2.5 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 OKR_DC_1_C PF03711.15 EKX54649.1 - 0.087 13.1 0.0 6.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, C-terminal domain DUF1465 PF07323.12 EKX54649.1 - 0.18 11.7 6.5 0.27 11.1 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) FlaC_arch PF05377.11 EKX54649.1 - 0.47 10.9 4.5 0.51 10.8 0.6 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) OmpH PF03938.14 EKX54649.1 - 0.55 10.6 9.7 0.81 10.0 9.7 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) RRN3 PF05327.11 EKX54649.1 - 1.3 7.5 3.1 1.5 7.3 3.1 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 zf-CpG_bind_C PF12269.8 EKX54649.1 - 1.5 8.6 7.1 2.1 8.1 7.1 1.1 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain CDC45 PF02724.14 EKX54649.1 - 3.1 6.0 10.1 4.1 5.6 10.1 1.0 1 0 0 1 1 1 0 CDC45-like protein GBP_C PF02841.14 EKX54649.1 - 3.1 7.1 12.0 4.3 6.7 12.0 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain WD40 PF00400.32 EKX54650.1 - 2.6e-05 24.9 14.0 0.14 13.1 0.3 6.7 7 0 0 7 7 7 2 WD domain, G-beta repeat WD40_like PF17005.5 EKX54650.1 - 0.11 11.8 0.4 3 7.1 0.0 2.6 3 0 0 3 3 3 0 WD40-like domain Apt1 PF10351.9 EKX54650.1 - 0.98 8.2 8.6 1.5 7.6 8.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ion_trans PF00520.31 EKX54651.1 - 2.2e-24 86.1 21.1 3.4e-22 78.9 21.1 2.2 1 1 0 1 1 1 1 Ion transport protein PH PF00169.29 EKX54651.1 - 1.4e-05 25.5 0.0 3.9e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 PH domain EF-hand_1 PF00036.32 EKX54651.1 - 0.00015 21.0 0.0 0.012 15.1 0.0 3.1 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EKX54651.1 - 0.0002 21.7 0.1 1.1 9.8 0.1 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EKX54651.1 - 0.0027 17.5 0.0 0.68 10.0 0.0 3.3 2 0 0 2 2 2 1 EF-hand domain FliS PF02561.14 EKX54651.1 - 0.05 13.9 2.0 0.14 12.4 0.1 2.7 4 0 0 4 4 4 0 Flagellar protein FliS Tmemb_9 PF05434.11 EKX54651.1 - 1.4 8.9 3.6 1 9.3 0.1 2.5 3 0 0 3 3 3 0 TMEM9 PKD_channel PF08016.12 EKX54651.1 - 3.7 6.1 17.8 1 8.0 0.3 2.7 2 1 0 2 2 2 0 Polycystin cation channel NPV_P10 PF05531.12 EKX54651.1 - 4.8 7.7 6.3 10 6.7 0.5 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Presenilin PF01080.17 EKX54652.1 - 9.1e-86 288.1 27.9 3.3e-53 180.9 8.6 2.0 1 1 1 2 2 2 2 Presenilin Peptidase_A22B PF04258.13 EKX54652.1 - 0.0016 18.0 9.8 0.0073 15.9 9.8 2.0 1 1 0 1 1 1 1 Signal peptide peptidase DUF4407 PF14362.6 EKX54652.1 - 7.5 5.8 10.5 1.6 8.0 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PDZ PF00595.24 EKX54654.1 - 3.6e-26 91.3 2.4 3e-08 33.9 0.6 3.3 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 EKX54654.1 - 4.7e-20 71.7 1.1 1.6e-07 31.6 0.1 3.2 3 0 0 3 3 3 3 PDZ domain PDZ_6 PF17820.1 EKX54654.1 - 2e-19 69.2 0.3 1.1e-05 25.1 0.0 3.4 3 0 0 3 3 3 3 PDZ domain Tricorn_PDZ PF14685.6 EKX54654.1 - 9.2e-09 35.2 0.3 0.0056 16.6 0.1 3.6 3 0 0 3 3 3 3 Tricorn protease PDZ domain GRASP55_65 PF04495.14 EKX54654.1 - 0.00011 22.5 0.0 0.078 13.3 0.0 2.6 2 1 1 3 3 3 2 GRASP55/65 PDZ-like domain PDZ_4 PF17816.1 EKX54654.1 - 0.029 14.7 0.6 11 6.4 0.1 2.6 2 1 0 2 2 2 0 PDZ domain Ras PF00071.22 EKX54655.1 - 1.5e-32 112.4 0.1 1.7e-32 112.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EKX54655.1 - 5.3e-27 94.4 0.0 7e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EKX54655.1 - 8.4e-11 41.6 0.1 1e-10 41.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EKX54655.1 - 0.00018 20.9 0.0 0.0002 20.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EKX54655.1 - 0.0089 15.8 0.1 0.018 14.8 0.0 1.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 EKX54655.1 - 0.065 12.4 0.2 7.2 5.7 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit TniB PF05621.11 EKX54655.1 - 0.13 11.6 0.0 0.49 9.8 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein DAO PF01266.24 EKX54656.1 - 9.5e-26 91.2 2.2 5.2e-25 88.8 2.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EKX54656.1 - 0.057 12.6 0.5 0.5 9.6 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EKX54656.1 - 0.33 11.2 3.0 0.75 10.1 3.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EKX54656.1 - 1.1 9.3 2.5 1.6 8.7 0.4 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding ParcG PF10274.9 EKX54657.1 - 4.2e-22 79.2 0.1 6.1e-22 78.6 0.1 1.2 1 0 0 1 1 1 1 Parkin co-regulated protein Mg_trans_NIPA PF05653.14 EKX54658.1 - 5.2e-67 226.0 19.9 5.2e-67 226.0 19.9 1.5 1 1 1 2 2 2 1 Magnesium transporter NIPA EamA PF00892.20 EKX54658.1 - 1.4e-05 25.3 4.7 1.4e-05 25.3 4.7 3.7 2 1 1 3 3 3 1 EamA-like transporter family PSI_integrin PF17205.3 EKX54658.1 - 0.048 13.4 9.8 0.22 11.3 0.3 2.7 2 0 0 2 2 2 0 Integrin plexin domain PSI PF01437.25 EKX54658.1 - 0.35 11.4 19.1 2.6 8.6 9.9 2.6 2 0 0 2 2 2 0 Plexin repeat PLAC8 PF04749.17 EKX54659.1 - 9.6e-10 39.4 7.8 1.2e-09 39.0 7.8 1.1 1 0 0 1 1 1 1 PLAC8 family TPR_2 PF07719.17 EKX54660.1 - 8.4e-06 25.5 0.1 0.0085 16.1 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX54660.1 - 1.9e-05 24.5 0.1 0.13 12.6 0.0 4.0 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX54660.1 - 5.2e-05 22.9 0.0 0.0026 17.5 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX54660.1 - 8.6e-05 23.0 0.1 0.0012 19.3 0.0 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 EKX54660.1 - 0.004 17.7 0.3 1.1 10.1 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX54660.1 - 0.0052 17.5 0.2 19 6.4 0.1 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EKX54660.1 - 0.034 14.8 0.3 4.3 8.1 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EKX54660.1 - 0.038 13.7 0.0 0.14 11.9 0.0 1.9 1 0 0 1 1 1 0 TPR repeat TPR_6 PF13174.6 EKX54660.1 - 0.094 13.4 0.3 23 5.9 0.1 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX54660.1 - 0.11 12.8 0.3 8.9 6.7 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat Ribosomal_L13e PF01294.18 EKX54662.1 - 7.6e-70 234.4 3.7 7.6e-70 234.4 3.7 1.3 2 0 0 2 2 2 1 Ribosomal protein L13e zf-RING_2 PF13639.6 EKX54663.1 - 2.5e-13 50.1 7.6 2.8e-13 50.0 7.6 1.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX54663.1 - 3.3e-12 46.1 6.6 4.3e-12 45.7 6.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EKX54663.1 - 4.1e-11 42.5 5.3 5.1e-11 42.2 5.3 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX54663.1 - 6.8e-10 39.1 9.6 1e-09 38.5 9.6 1.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EKX54663.1 - 1.7e-08 34.1 2.6 1.7e-08 34.1 2.6 1.4 2 0 0 2 2 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EKX54663.1 - 1.1e-06 28.5 2.6 1.3e-06 28.3 0.8 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EKX54663.1 - 1.4e-06 28.3 6.1 1.7e-05 24.8 6.0 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EKX54663.1 - 3.1e-06 26.9 4.1 0.0019 18.0 1.0 2.0 2 0 0 2 2 2 2 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 EKX54663.1 - 9.6e-06 25.5 6.0 1.5e-05 24.8 6.1 1.3 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EKX54663.1 - 1.5e-05 24.8 7.5 0.0015 18.4 8.2 2.0 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EKX54663.1 - 2.9e-05 23.8 7.9 7.3e-05 22.6 8.0 1.6 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 EKX54663.1 - 0.00046 20.0 1.4 0.24 11.3 0.3 2.2 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-C3HC4_4 PF15227.6 EKX54663.1 - 0.00085 19.4 3.0 0.008 16.3 0.6 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 EKX54663.1 - 0.002 17.9 3.7 0.0028 17.4 3.7 1.3 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 EKX54663.1 - 0.0076 16.5 7.1 0.018 15.3 7.1 1.6 1 1 1 2 2 2 1 RING-like domain zf-WRNIP1_ubi PF18279.1 EKX54663.1 - 0.017 15.7 2.2 2.3 9.0 0.2 2.8 3 0 0 3 3 3 0 Werner helicase-interacting protein 1 ubiquitin-binding domain FANCL_C PF11793.8 EKX54663.1 - 0.021 15.0 10.6 0.16 12.2 4.8 2.8 1 1 1 2 2 2 0 FANCL C-terminal domain RINGv PF12906.7 EKX54663.1 - 0.031 14.4 6.8 0.096 12.8 6.8 1.7 1 1 0 1 1 1 0 RING-variant domain YacG PF03884.14 EKX54663.1 - 0.041 13.6 1.5 0.041 13.6 1.5 2.0 1 1 1 2 2 2 0 DNA gyrase inhibitor YacG zf-Di19 PF05605.12 EKX54663.1 - 0.043 14.1 6.1 0.43 10.9 0.8 2.2 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_5 PF17121.5 EKX54663.1 - 0.08 12.8 8.5 0.73 9.8 8.5 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EKX54663.1 - 0.16 11.6 8.2 0.41 10.3 8.2 1.8 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF4451 PF14616.6 EKX54663.1 - 0.34 11.1 4.8 3.4 7.9 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) zf-C3H2C3 PF17122.5 EKX54663.1 - 0.49 10.5 10.9 0.57 10.3 4.8 2.7 2 1 0 2 2 2 0 Zinc-finger Vps39_2 PF10367.9 EKX54663.1 - 0.89 10.0 6.3 0.43 11.1 1.0 2.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 DUF2310 PF10071.9 EKX54663.1 - 1.9 7.7 5.5 0.44 9.8 1.5 1.8 1 1 1 2 2 2 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) Zn-C2H2_12 PF18112.1 EKX54663.1 - 2.1 8.9 10.3 5 7.7 1.3 2.7 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain HSP70 PF00012.20 EKX54665.1 - 6.5e-131 437.4 3.5 6.7e-130 434.1 3.5 2.0 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EKX54665.1 - 4.9e-12 45.3 2.4 2.2e-07 30.0 0.2 3.2 3 0 0 3 3 3 2 MreB/Mbl protein PilM_2 PF11104.8 EKX54665.1 - 0.0028 16.7 0.0 0.0058 15.7 0.0 1.5 1 0 0 1 1 1 1 Type IV pilus assembly protein PilM; Peptidase_M22 PF00814.25 EKX54665.1 - 0.013 15.2 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Glycoprotease family RCC1 PF00415.18 EKX54666.1 - 5.3e-59 196.6 18.3 2.6e-13 50.4 0.0 6.5 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX54666.1 - 8.9e-35 117.8 24.8 8.4e-08 31.8 0.5 6.3 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Kelch_4 PF13418.6 EKX54666.1 - 1 9.5 3.4 64 3.7 0.1 3.6 3 0 0 3 3 3 0 Galactose oxidase, central domain LRR_4 PF12799.7 EKX54667.1 - 2.4e-17 62.7 6.6 7.7e-08 32.5 0.1 3.5 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX54667.1 - 7e-11 41.9 0.0 5.7e-06 25.9 0.1 2.0 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 EKX54667.1 - 4.9e-10 39.0 8.1 1.6e-05 24.5 0.3 3.4 1 1 3 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 EKX54667.1 - 0.004 17.5 3.6 45 5.2 0.1 4.7 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 EKX54667.1 - 0.6 10.3 9.8 16 5.9 0.1 4.9 6 0 0 6 6 6 0 Leucine Rich repeat EGF_3 PF12947.7 EKX54668.1 - 0.37 11.0 8.3 85 3.5 0.1 4.1 4 0 0 4 4 4 0 EGF domain Nup160 PF11715.8 EKX54668.1 - 1.4 7.4 4.3 10 4.6 0.8 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PLL PF18587.1 EKX54668.1 - 4.3 7.5 7.6 9.8 6.3 0.4 3.0 1 1 2 3 3 3 0 PTX/LNS-Like (PLL) domain Methyltransf_31 PF13847.6 EKX54669.1 - 0.00054 19.8 0.1 0.00091 19.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EKX54669.1 - 0.015 15.3 6.7 0.018 15.0 1.4 2.9 1 1 1 2 2 2 0 Methyltransferase domain MTS PF05175.14 EKX54669.1 - 0.015 14.8 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain FAD_binding_1 PF00667.20 EKX54670.1 - 5.5e-56 189.6 0.0 8.6e-56 189.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EKX54670.1 - 2.8e-35 121.6 0.8 1.1e-34 119.7 0.5 2.1 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 EKX54670.1 - 1.6e-15 57.7 0.0 4.9e-15 56.1 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DrsE PF02635.15 EKX54670.1 - 0.017 15.5 0.0 0.038 14.4 0.0 1.5 1 0 0 1 1 1 0 DsrE/DsrF-like family NAD_binding_6 PF08030.12 EKX54670.1 - 0.088 12.9 0.1 11 6.1 0.0 2.7 1 1 1 2 2 2 0 Ferric reductase NAD binding domain Paramecium_SA PF01508.16 EKX54671.1 - 0.47 10.9 5.7 2.7 8.5 0.3 2.3 2 0 0 2 2 2 0 Paramecium surface antigen domain RPN1_RPN2_N PF17781.1 EKX54672.1 - 8.9e-115 383.3 0.0 1.8e-114 382.3 0.1 1.5 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 EKX54672.1 - 1.3e-30 105.1 0.0 2.8e-30 104.1 0.0 1.6 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 EKX54672.1 - 1.4e-17 63.1 28.4 3.5e-06 27.2 0.1 10.3 11 0 0 11 11 11 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EKX54672.1 - 8.4e-05 22.9 1.7 0.15 12.5 0.0 4.3 4 0 0 4 4 4 2 HEAT repeats Lipase_GDSL_2 PF13472.6 EKX54673.1 - 1.2e-18 68.2 0.1 1.5e-18 67.9 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EKX54673.1 - 1.8e-09 37.9 0.0 2.2e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase RNA_pol PF00940.19 EKX54674.1 - 4.6e-150 500.1 0.0 2.2e-149 497.8 0.0 2.0 1 1 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EKX54674.1 - 5.8e-40 137.7 0.0 1e-39 136.9 0.0 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Ferrochelatase PF00762.19 EKX54675.1 - 7.2e-111 370.3 0.0 9e-111 369.9 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase CbiX PF01903.17 EKX54675.1 - 5e-05 23.6 0.0 0.0013 19.1 0.0 2.6 2 0 0 2 2 2 1 CbiX Chloroa_b-bind PF00504.21 EKX54675.1 - 0.0011 19.5 0.0 0.0022 18.6 0.0 1.5 1 0 0 1 1 1 1 Chlorophyll A-B binding protein MMR_HSR1_Xtn PF16897.5 EKX54676.1 - 6.4e-36 122.6 0.1 1.2e-35 121.7 0.1 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 EKX54676.1 - 3.3e-20 71.9 0.0 5.8e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 EKX54676.1 - 5.9e-20 71.5 0.0 1.2e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EKX54676.1 - 2.4e-11 43.4 0.0 1.2e-09 37.9 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EKX54676.1 - 0.00037 20.6 0.0 0.2 11.7 0.0 2.5 2 0 0 2 2 2 2 Dynamin family MeaB PF03308.16 EKX54676.1 - 0.0087 15.1 0.1 0.02 13.9 0.1 1.6 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 EKX54676.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 AIG1 family ABC_tran PF00005.27 EKX54676.1 - 0.057 13.9 0.0 0.22 12.0 0.0 1.9 2 0 0 2 2 2 0 ABC transporter DnaJ_CXXCXGXG PF00684.19 EKX54677.1 - 0.00039 20.7 71.6 0.0092 16.3 25.4 3.9 1 1 3 4 4 4 4 DnaJ central domain Pkinase PF00069.25 EKX54679.1 - 1e-47 162.7 0.1 1.3e-47 162.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX54679.1 - 4e-32 111.5 0.3 7.6e-32 110.6 0.3 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX54679.1 - 4.7e-05 22.3 0.1 0.0003 19.7 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 EKX54679.1 - 0.0049 15.9 0.0 0.0063 15.5 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.6 EKX54679.1 - 0.049 12.9 0.0 0.096 12.0 0.0 1.5 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 EKX54679.1 - 0.054 13.1 0.0 0.12 12.0 0.0 1.7 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EKX54679.1 - 0.14 11.5 0.1 0.24 10.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EKX54680.1 - 2.7e-48 164.6 0.0 3.1e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX54680.1 - 2.9e-35 121.8 0.2 4.8e-35 121.1 0.2 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX54680.1 - 5e-07 28.8 0.1 0.0019 17.1 0.0 2.1 1 1 0 2 2 2 2 Fungal protein kinase Haspin_kinase PF12330.8 EKX54680.1 - 0.0024 16.9 0.2 0.0043 16.1 0.2 1.5 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EKX54680.1 - 0.0076 16.2 0.0 0.04 13.8 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EKX54680.1 - 0.021 14.1 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EKX54680.1 - 0.11 11.8 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CBM_20 PF00686.19 EKX54681.1 - 4.7e-12 45.7 0.0 9.1e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain PDZ_6 PF17820.1 EKX54681.1 - 3.5e-06 26.7 0.0 6.4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX54681.1 - 0.00042 20.6 0.0 0.00074 19.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX54681.1 - 0.01 16.1 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 PDZ domain Pkinase PF00069.25 EKX54682.1 - 6.9e-62 209.2 0.0 8.4e-62 208.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX54682.1 - 1e-32 113.5 0.0 1.2e-32 113.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX54682.1 - 8.1e-05 22.1 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EKX54682.1 - 0.0011 17.8 0.0 0.0016 17.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EKX54682.1 - 0.015 14.3 0.0 0.019 14.0 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 EKX54682.1 - 0.02 14.5 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 EKX54682.1 - 0.096 12.0 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX54682.1 - 0.13 12.2 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family WaaY PF06176.11 EKX54682.1 - 0.13 11.8 0.1 0.2 11.2 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) RRM_9 PF18444.1 EKX54683.1 - 2.7e-05 23.9 0.0 7.3e-05 22.5 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif DDA1 PF10172.9 EKX54684.1 - 1.2e-06 28.7 1.4 3.3e-06 27.3 0.0 2.3 3 0 0 3 3 3 1 Det1 complexing ubiquitin ligase PGA2 PF07543.12 EKX54684.1 - 0.054 13.5 3.4 0.082 12.9 3.4 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 Bromodomain PF00439.25 EKX54685.1 - 2.7e-19 69.0 0.5 2.9e-19 68.9 0.5 1.0 1 0 0 1 1 1 1 Bromodomain EF-hand_8 PF13833.6 EKX54686.1 - 0.18 11.6 1.5 0.33 10.8 0.3 2.0 2 0 0 2 2 2 0 EF-hand domain pair Ank_5 PF13857.6 EKX54687.1 - 4.5e-14 52.3 5.0 2.4e-09 37.3 0.3 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX54687.1 - 7.5e-14 52.1 1.5 3.5e-11 43.5 1.3 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX54687.1 - 4.8e-12 45.8 3.6 0.00023 21.5 0.3 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EKX54687.1 - 1.8e-11 43.1 0.9 6.3e-05 23.1 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EKX54687.1 - 2e-10 41.0 3.5 2.4e-05 24.8 0.4 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) fn3 PF00041.21 EKX54688.1 - 3e-15 56.3 0.0 0.0078 16.5 0.0 6.2 6 0 0 6 6 6 4 Fibronectin type III domain Bromodomain PF00439.25 EKX54688.1 - 0.14 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Bromodomain Mito_fiss_reg PF05308.11 EKX54688.1 - 0.31 11.1 3.0 0.8 9.7 3.0 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator VIR_N PF15912.5 EKX54688.1 - 1.8 8.1 4.9 4.4 6.8 3.1 2.1 2 0 0 2 2 2 0 Virilizer, N-terminal DUF155 PF02582.14 EKX54689.1 - 2.2e-41 141.9 0.0 3.6e-40 137.9 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 Synaptobrevin PF00957.21 EKX54690.1 - 3.7e-14 52.3 0.5 5.8e-14 51.6 0.5 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EKX54690.1 - 8.5e-11 41.7 0.0 1.5e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain CorA PF01544.18 EKX54690.1 - 0.12 11.6 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2514 PF10721.9 EKX54691.1 - 0.36 10.9 10.6 0.047 13.7 3.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2514) Mt_ATP-synt_B PF05405.14 EKX54691.1 - 7.6 6.1 10.9 18 4.9 10.9 1.6 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) EAGR_box PF16713.5 EKX54692.1 - 0.079 12.7 0.1 0.2 11.3 0.1 1.6 1 0 0 1 1 1 0 Enriched in aromatic and glycine Residues box TBCC PF07986.12 EKX54693.1 - 5.3e-20 71.4 1.0 1.1e-19 70.4 0.6 1.7 2 0 0 2 2 2 1 Tubulin binding cofactor C CAP_C PF08603.11 EKX54693.1 - 0.0028 17.3 0.8 0.0057 16.3 0.8 1.5 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TLD PF07534.16 EKX54694.1 - 3.3e-34 118.1 0.6 4.4e-34 117.7 0.6 1.2 1 0 0 1 1 1 1 TLD LRR_9 PF14580.6 EKX54695.1 - 3e-12 46.4 6.3 5.1e-08 32.6 0.1 2.7 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 EKX54695.1 - 1.9e-11 44.0 21.1 0.0001 22.6 0.9 4.4 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EKX54695.1 - 2.3e-07 30.5 14.7 0.00033 20.3 5.6 3.5 2 1 2 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 EKX54695.1 - 0.0046 16.9 7.7 1.2 9.4 0.3 4.0 3 0 0 3 3 3 2 Leucine Rich repeat Arg_decarbox_C PF17944.1 EKX54695.1 - 0.24 12.0 2.9 1.9 9.1 0.7 3.4 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension LRR_1 PF00560.33 EKX54695.1 - 1.5 9.7 9.9 74 4.5 0.0 4.8 3 1 0 3 3 3 0 Leucine Rich Repeat TPR_12 PF13424.6 EKX54697.1 - 1.6e-13 50.7 0.8 6.6e-11 42.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX54697.1 - 2.9e-09 36.3 2.8 0.0016 18.2 0.0 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX54697.1 - 1.9e-07 30.7 2.7 0.061 13.5 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX54697.1 - 0.00018 21.5 4.6 8.5 6.9 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX54697.1 - 0.00084 19.2 1.9 0.16 12.0 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX54697.1 - 0.0013 18.5 0.0 0.047 13.6 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat p25-alpha PF05517.12 EKX54697.1 - 0.0049 17.0 0.4 5.6 7.1 0.0 2.9 3 0 0 3 3 3 2 p25-alpha Ge1_WD40 PF16529.5 EKX54698.1 - 5.4e-16 58.5 0.0 1.6e-11 43.8 0.0 2.2 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ARGLU PF15346.6 EKX54698.1 - 0.017 15.0 19.7 0.058 13.3 8.2 2.3 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 PIN_9 PF18477.1 EKX54698.1 - 0.22 11.9 0.1 0.22 11.9 0.1 2.9 3 0 0 3 3 3 0 PIN like domain WD40 PF00400.32 EKX54698.1 - 0.22 12.4 2.9 24 6.0 0.3 4.2 4 1 0 4 4 4 0 WD domain, G-beta repeat YpjP PF14005.6 EKX54698.1 - 0.38 10.8 3.1 12 6.0 0.2 2.8 2 0 0 2 2 2 0 YpjP-like protein 3-HAO PF06052.12 EKX54700.1 - 0.057 13.1 0.0 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase VWA_2 PF13519.6 EKX54701.1 - 0.0014 19.3 2.4 0.18 12.4 0.3 3.8 2 2 1 3 3 3 1 von Willebrand factor type A domain Med9 PF07544.13 EKX54701.1 - 0.013 15.6 1.7 0.013 15.6 1.7 3.0 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 KASH_CCD PF14662.6 EKX54701.1 - 0.02 14.7 18.0 0.22 11.3 5.3 2.7 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH TPR_MLP1_2 PF07926.12 EKX54701.1 - 0.1 12.7 21.3 0.72 9.9 6.4 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Shugoshin_N PF07558.11 EKX54701.1 - 0.37 10.7 5.3 4.2 7.3 1.2 2.7 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region bZIP_2 PF07716.15 EKX54701.1 - 5.8 7.1 16.4 0.78 9.9 3.0 3.7 3 0 0 3 3 3 0 Basic region leucine zipper Cauli_AT PF03233.13 EKX54701.1 - 6.5 6.7 8.2 1.3 9.0 1.1 2.8 3 0 0 3 3 3 0 Aphid transmission protein Mito_fiss_reg PF05308.11 EKX54701.1 - 6.7 6.7 9.0 1.8 8.6 2.9 2.7 2 1 0 2 2 2 0 Mitochondrial fission regulator Methyltransf_3 PF01596.17 EKX54702.1 - 6.6e-37 126.7 0.2 7.3e-37 126.6 0.2 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EKX54702.1 - 3.2e-10 41.0 0.0 4.5e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX54702.1 - 0.00037 21.1 0.1 0.00058 20.5 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EKX54702.1 - 0.0009 19.0 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 EKX54702.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 EKX54702.1 - 0.018 14.8 0.1 0.024 14.4 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase domain AAA_31 PF13614.6 EKX54702.1 - 0.042 13.8 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Methyltrans_SAM PF10672.9 EKX54702.1 - 0.071 12.2 0.0 0.091 11.9 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase Methyltransf_23 PF13489.6 EKX54702.1 - 0.073 12.9 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EKX54702.1 - 0.076 13.7 0.1 0.15 12.7 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Nrap_D2 PF17403.2 EKX54702.1 - 0.081 12.7 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain ATP19 PF11022.8 EKX54703.1 - 0.012 16.0 0.4 0.13 12.7 0.1 2.3 2 0 0 2 2 2 0 ATP synthase subunit K DUF4381 PF14316.6 EKX54703.1 - 0.027 14.7 0.5 0.049 13.9 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) WHEP-TRS PF00458.20 EKX54703.1 - 0.028 14.5 5.8 0.049 13.8 5.8 1.3 1 0 0 1 1 1 0 WHEP-TRS domain MSC PF09402.10 EKX54703.1 - 0.036 13.5 0.2 0.045 13.2 0.2 1.3 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Ctr PF04145.15 EKX54703.1 - 0.075 13.6 1.1 0.11 13.1 1.1 1.4 1 1 0 1 1 1 0 Ctr copper transporter family DUF2615 PF11027.8 EKX54703.1 - 0.085 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) EphA2_TM PF14575.6 EKX54703.1 - 0.096 13.6 0.1 0.19 12.6 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FbpA PF05833.11 EKX54703.1 - 0.19 10.5 4.7 0.26 10.0 4.7 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) SieB PF14163.6 EKX54703.1 - 0.21 11.1 1.6 0.34 10.4 1.6 1.3 1 0 0 1 1 1 0 Super-infection exclusion protein B LapA_dom PF06305.11 EKX54703.1 - 0.64 9.9 6.8 15 5.5 6.8 2.2 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Sigma70_ner PF04546.13 EKX54704.1 - 0.21 11.5 3.9 0.19 11.6 3.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region SDA1 PF05285.12 EKX54704.1 - 0.44 9.9 6.2 0.37 10.2 6.2 1.1 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.11 EKX54704.1 - 0.75 8.3 3.4 0.74 8.3 3.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GCIP PF13324.6 EKX54704.1 - 1.8 8.1 4.5 1.6 8.2 4.5 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting RXT2_N PF08595.11 EKX54704.1 - 3.2 7.8 6.7 2.5 8.1 5.7 1.4 2 0 0 2 2 2 0 RXT2-like, N-terminal Nop14 PF04147.12 EKX54704.1 - 7 4.7 10.4 7.2 4.7 10.4 1.0 1 0 0 1 1 1 0 Nop14-like family CHORD PF04968.12 EKX54706.1 - 4.1e-05 24.2 1.7 9.1e-05 23.1 1.7 1.6 1 0 0 1 1 1 1 CHORD DUF3583 PF12126.8 EKX54706.1 - 0.045 13.2 0.6 0.078 12.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) DUF1572 PF07609.11 EKX54706.1 - 0.082 12.7 1.9 0.68 9.7 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1572) FapA PF03961.13 EKX54706.1 - 0.19 10.3 1.3 0.24 9.9 1.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A PspB PF06667.12 EKX54706.1 - 0.24 11.5 1.2 5.7 7.1 0.1 2.4 2 0 0 2 2 2 0 Phage shock protein B DUF1967 PF09269.11 EKX54707.1 - 0.031 14.2 0.1 0.12 12.3 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Enolase_C PF00113.22 EKX54708.1 - 1.1e-15 57.7 0.0 2.2e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EKX54708.1 - 0.018 15.2 0.1 0.04 14.1 0.1 1.6 1 0 0 1 1 1 0 Enolase, N-terminal domain COX16 PF14138.6 EKX54708.1 - 0.36 11.4 1.6 2.2 8.9 0.1 2.7 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 DUF1315 PF07023.12 EKX54708.1 - 4.8 7.3 5.8 3.4 7.8 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1315) bZIP_1 PF00170.21 EKX54709.1 - 8.5e-11 41.8 25.7 1e-07 31.9 6.6 3.1 2 1 1 3 3 3 3 bZIP transcription factor bZIP_2 PF07716.15 EKX54709.1 - 1.6e-06 28.1 3.7 1.6e-06 28.1 3.7 3.7 3 1 1 4 4 3 3 Basic region leucine zipper bZIP_Maf PF03131.17 EKX54709.1 - 4.5e-05 23.9 20.8 0.0064 17.0 5.8 2.5 2 0 0 2 2 2 2 bZIP Maf transcription factor DivIC PF04977.15 EKX54709.1 - 0.047 13.4 0.1 0.047 13.4 0.1 2.6 2 1 0 2 2 2 0 Septum formation initiator DUF4878 PF12870.7 EKX54709.1 - 0.059 13.7 0.2 0.059 13.7 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4878) YabA PF06156.13 EKX54709.1 - 0.084 13.5 0.7 0.084 13.5 0.7 2.4 2 1 1 3 3 3 0 Initiation control protein YabA SlyX PF04102.12 EKX54709.1 - 0.099 13.3 0.4 0.099 13.3 0.4 3.2 2 2 0 3 3 3 0 SlyX DUF2205 PF10224.9 EKX54709.1 - 0.8 9.7 7.7 0.077 13.0 1.7 2.5 2 1 0 2 2 2 0 Short coiled-coil protein DUF1465 PF07323.12 EKX54709.1 - 1.4 8.7 8.4 0.25 11.2 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) Shugoshin_N PF07558.11 EKX54709.1 - 2.1 8.3 8.2 0.17 11.7 0.8 2.5 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Rsc14 PF08586.10 EKX54709.1 - 7.7 7.4 6.7 44 5.0 0.5 2.6 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit bZIP_1 PF00170.21 EKX54710.1 - 2.3e-09 37.2 33.1 7.1e-08 32.4 9.7 2.8 3 0 0 3 3 3 2 bZIP transcription factor bZIP_2 PF07716.15 EKX54710.1 - 3e-07 30.4 4.5 3e-07 30.4 4.5 3.6 3 1 1 4 4 4 2 Basic region leucine zipper bZIP_Maf PF03131.17 EKX54710.1 - 5.1e-07 30.1 18.8 3e-05 24.4 6.2 2.5 2 0 0 2 2 2 2 bZIP Maf transcription factor Cep57_CLD_2 PF14197.6 EKX54710.1 - 0.00034 20.6 2.9 0.001 19.1 2.9 1.9 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 YabA PF06156.13 EKX54710.1 - 0.0035 18.0 0.5 0.0035 18.0 0.5 2.1 2 1 0 2 2 2 1 Initiation control protein YabA Sec5 PF15469.6 EKX54710.1 - 0.12 12.1 2.0 0.21 11.4 2.0 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec5 TTKRSYEDQ PF10212.9 EKX54710.1 - 0.16 11.0 3.9 0.23 10.4 3.9 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Shugoshin_N PF07558.11 EKX54710.1 - 1 9.3 10.3 0.047 13.6 1.9 2.4 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region COG2 PF06148.11 EKX54710.1 - 2.2 8.4 5.9 6.1 6.9 4.5 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 RRM_1 PF00076.22 EKX54712.1 - 2.8e-14 52.7 0.0 1e-06 28.4 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PARP PF00644.20 EKX54714.1 - 1.1e-12 48.0 0.1 2.7e-08 33.6 0.1 3.0 2 1 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain PPR_3 PF13812.6 EKX54715.1 - 0.0039 17.2 0.0 0.01 15.9 0.0 1.7 1 0 0 1 1 1 1 Pentatricopeptide repeat domain Laminin_B PF00052.18 EKX54715.1 - 0.12 12.3 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Laminin B (Domain IV) PPR_1 PF12854.7 EKX54715.1 - 0.14 11.9 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 PPR repeat RWP-RK PF02042.15 EKX54716.1 - 5.9e-15 55.0 0.0 1.2e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain HTH_6 PF01418.17 EKX54716.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family RWP-RK PF02042.15 EKX54717.1 - 1.8e-14 53.4 0.0 3.4e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain HTH_6 PF01418.17 EKX54717.1 - 0.14 12.2 0.1 0.35 10.9 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family Codanin-1_C PF15296.6 EKX54718.1 - 0.025 14.7 0.1 0.027 14.5 0.1 1.1 1 0 0 1 1 1 0 Codanin-1 C-terminus Anoctamin PF04547.12 EKX54719.1 - 9.5e-92 308.2 10.0 1.4e-91 307.6 10.0 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel AMP_N PF05195.16 EKX54719.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain DUF4335 PF14233.6 EKX54719.1 - 0.22 11.4 0.7 0.43 10.5 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) zf-3CxxC PF13695.6 EKX54719.1 - 0.26 11.8 3.7 2.2 8.8 0.0 3.3 3 0 0 3 3 3 0 Zinc-binding domain PX PF00787.24 EKX54720.1 - 9.3e-14 51.4 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 PX domain PA PF02225.22 EKX54720.1 - 3.6e-06 26.9 0.0 6.1e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 PA domain MORN PF02493.20 EKX54720.1 - 0.0011 18.7 5.9 0.024 14.5 0.3 3.4 3 0 0 3 3 3 2 MORN repeat DUF3431 PF11913.8 EKX54721.1 - 0.038 13.8 0.4 0.038 13.8 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3431) RIBIOP_C PF04950.12 EKX54723.1 - 4.3e-79 266.0 0.0 4.9e-79 265.8 0.0 1.0 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Myb_DNA-binding PF00249.31 EKX54724.1 - 1.1e-07 32.0 0.2 3.4e-07 30.3 0.2 1.8 1 1 0 1 1 1 1 Myb-like DNA-binding domain Aminotran_4 PF01063.19 EKX54725.1 - 4.2e-05 23.5 0.0 7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Amino-transferase class IV LpxI_C PF06230.11 EKX54725.1 - 0.023 14.5 0.1 0.057 13.3 0.1 1.6 1 0 0 1 1 1 0 LpxI C-terminal domain DUF1093 PF06486.11 EKX54725.1 - 0.092 13.4 0.2 0.27 11.9 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1093) WD40 PF00400.32 EKX54727.1 - 2.4e-26 91.4 10.6 2.8e-08 34.3 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX54727.1 - 1.6e-08 34.7 0.0 0.00029 21.1 0.0 3.9 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EKX54727.1 - 6.2e-06 25.1 1.3 0.29 9.7 0.0 3.4 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EKX54727.1 - 1.1e-05 24.6 0.0 0.18 10.7 0.0 3.4 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EKX54727.1 - 0.00073 19.0 0.0 0.00084 18.8 0.0 1.2 1 0 0 1 1 1 1 WD40-like domain EF-hand_7 PF13499.6 EKX54728.1 - 0.002 18.5 0.1 4.5 7.8 0.0 3.0 2 1 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EKX54728.1 - 0.0032 16.9 0.1 13 5.7 0.1 3.8 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 EKX54728.1 - 0.0055 16.5 0.1 10 6.3 0.1 3.5 3 1 1 4 4 4 2 EF-hand domain Atx10homo_assoc PF09759.9 EKX54729.1 - 0.0028 17.7 1.8 0.37 10.8 0.2 4.1 3 2 2 5 5 5 2 Spinocerebellar ataxia type 10 protein domain Mitoc_L55 PF09776.9 EKX54729.1 - 1.7 8.4 4.0 1.2 8.9 0.2 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L55 RWP-RK PF02042.15 EKX54730.1 - 3.6e-15 55.7 0.0 3.7e-14 52.4 0.0 2.1 2 0 0 2 2 2 1 RWP-RK domain RWP-RK PF02042.15 EKX54731.1 - 1.9e-14 53.4 0.0 3e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain PGK PF00162.19 EKX54732.1 - 6.9e-148 492.6 1.9 7.8e-148 492.4 1.9 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase His_Phos_1 PF00300.22 EKX54733.1 - 4.6e-30 104.8 0.0 2.9e-22 79.3 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Collagen PF01391.18 EKX54734.1 - 3e-20 71.7 65.4 8.2e-09 35.1 31.2 3.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) TEX29 PF15839.5 EKX54734.1 - 0.024 15.2 0.0 0.043 14.4 0.0 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 29 protein RWP-RK PF02042.15 EKX54735.1 - 0.0023 17.8 0.0 0.0046 16.9 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain eIF-6 PF01912.18 EKX54735.1 - 0.095 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 eIF-6 family Hat1_N PF10394.9 EKX54736.1 - 3.8e-14 53.2 0.1 1.4e-13 51.4 0.1 2.1 1 1 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 EKX54736.1 - 1.3e-06 28.6 0.0 4e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EKX54736.1 - 6.5e-05 23.3 0.0 0.00015 22.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EKX54736.1 - 0.0012 18.8 0.0 0.003 17.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 EKX54736.1 - 0.0054 16.4 0.0 0.0098 15.6 0.0 1.6 1 0 0 1 1 1 1 MOZ/SAS family Noggin PF05806.12 EKX54736.1 - 0.0066 16.4 0.2 0.015 15.3 0.2 1.5 1 0 0 1 1 1 1 Noggin Acetyltransf_CG PF14542.6 EKX54736.1 - 0.036 14.2 0.0 0.073 13.2 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pkinase_Tyr PF07714.17 EKX54737.1 - 1e-09 38.1 0.3 3.7e-09 36.3 0.1 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EKX54737.1 - 4.4e-09 36.1 0.2 3e-08 33.4 0.2 2.6 1 1 0 1 1 1 1 Protein kinase domain Arm PF00514.23 EKX54737.1 - 0.037 14.1 22.8 2.3 8.4 0.0 10.0 13 0 0 13 13 13 0 Armadillo/beta-catenin-like repeat VHS PF00790.19 EKX54737.1 - 0.085 12.7 0.3 2.3 8.1 0.0 3.5 2 0 0 2 2 2 0 VHS domain Atx10homo_assoc PF09759.9 EKX54737.1 - 0.18 11.9 20.5 2.3 8.3 0.2 7.8 8 1 2 10 10 10 0 Spinocerebellar ataxia type 10 protein domain DUF3361 PF11841.8 EKX54737.1 - 0.56 10.1 44.3 0.29 11.1 0.4 9.7 8 3 2 11 11 11 0 Domain of unknown function (DUF3361) PNTB PF02233.16 EKX54738.1 - 1.4e-153 512.2 23.8 1.4e-153 512.2 23.8 2.5 2 2 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 EKX54738.1 - 1e-77 260.3 0.1 1e-77 260.3 0.1 2.8 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 EKX54738.1 - 8e-43 146.0 0.0 2e-42 144.7 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 EKX54738.1 - 1.4e-28 99.2 6.5 1.4e-28 99.2 6.5 4.3 2 1 3 5 5 5 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 EKX54738.1 - 7.3e-05 22.2 0.1 0.018 14.4 0.1 2.7 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PH PF00169.29 EKX54739.1 - 2.8e-07 31.0 0.4 5.9e-07 30.0 0.4 1.5 1 0 0 1 1 1 1 PH domain PH_2 PF08458.10 EKX54739.1 - 0.051 13.9 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 Plant pleckstrin homology-like region Na_K-ATPase PF00287.18 EKX54739.1 - 0.74 8.9 3.3 1.1 8.3 3.3 1.2 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain JAB PF01398.21 EKX54740.1 - 7.2e-15 55.0 0.0 1.6e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RWP-RK PF02042.15 EKX54741.1 - 1.9e-13 50.1 0.0 3.2e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain FRG2 PF15315.6 EKX54742.1 - 0.014 15.6 4.2 0.014 15.6 4.2 1.8 2 0 0 2 2 2 0 Facioscapulohumeral muscular dystrophy candidate 2 HATPase_c_4 PF13749.6 EKX54742.1 - 0.04 14.1 0.0 0.13 12.4 0.0 1.9 1 0 0 1 1 1 0 Putative ATP-dependent DNA helicase recG C-terminal Presenilin PF01080.17 EKX54742.1 - 2.5 6.8 5.7 3.2 6.4 5.7 1.1 1 0 0 1 1 1 0 Presenilin RPA43_OB PF17875.1 EKX54742.1 - 4.8 7.8 6.6 2.8 8.6 1.3 2.8 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I DUF4611 PF15387.6 EKX54742.1 - 5.6 7.3 11.9 8.7 6.6 8.9 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) PPP4R2 PF09184.11 EKX54742.1 - 6 6.4 13.9 9.6 5.7 13.9 1.2 1 0 0 1 1 1 0 PPP4R2 DUF3127 PF11325.8 EKX54743.1 - 1.4e-28 99.0 0.8 1.9e-28 98.5 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3127) LMF1 PF06762.14 EKX54744.1 - 2e-49 168.9 14.9 3.6e-40 138.4 5.9 2.8 3 1 0 3 3 3 2 Lipase maturation factor VKOR PF07884.14 EKX54744.1 - 8e-19 68.0 18.0 8e-19 68.0 18.0 4.1 5 0 0 5 5 5 1 Vitamin K epoxide reductase family PspB PF06667.12 EKX54744.1 - 3.2 7.9 5.4 43 4.3 0.9 3.7 3 0 0 3 3 3 0 Phage shock protein B PTH2 PF01981.16 EKX54745.1 - 2.5e-21 76.1 0.0 3e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF4166 PF13761.6 EKX54746.1 - 0.16 11.7 0.0 0.83 9.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4166) Ank_4 PF13637.6 EKX54747.1 - 1e-14 54.7 0.3 3.7e-11 43.3 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX54747.1 - 2.1e-11 44.3 0.0 3.2e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX54747.1 - 1.6e-10 41.0 0.6 3.1e-10 40.1 0.6 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX54747.1 - 9e-10 38.0 0.0 4.5e-06 26.6 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EKX54747.1 - 7.6e-06 26.1 0.1 0.00029 21.2 0.2 2.6 3 0 0 3 3 2 1 Ankyrin repeat Nop14 PF04147.12 EKX54747.1 - 0.00011 20.6 29.8 0.00013 20.3 29.8 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 EKX54747.1 - 0.036 12.4 24.4 0.054 11.8 24.4 1.3 1 0 0 1 1 1 0 CDC45-like protein PTPRCAP PF15713.5 EKX54747.1 - 0.048 13.9 27.9 0.047 14.0 26.2 1.9 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated SAPS PF04499.15 EKX54747.1 - 0.11 11.2 10.1 0.11 11.2 10.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 EKX54747.1 - 0.12 11.8 38.4 0.17 11.3 38.4 1.2 1 0 0 1 1 1 0 SDA1 Tim54 PF11711.8 EKX54747.1 - 0.16 10.7 8.1 0.25 10.1 8.1 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Mpp10 PF04006.12 EKX54747.1 - 0.2 10.0 35.2 0.27 9.6 35.2 1.1 1 0 0 1 1 1 0 Mpp10 protein RR_TM4-6 PF06459.12 EKX54747.1 - 0.33 10.7 11.9 0.53 10.1 11.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sec62 PF03839.16 EKX54747.1 - 0.39 10.2 0.7 0.53 9.8 0.7 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 SpoIIIAH PF12685.7 EKX54747.1 - 0.65 9.8 13.6 1.1 9.1 13.6 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein BUD22 PF09073.10 EKX54747.1 - 2.4 7.4 36.7 4.1 6.7 36.7 1.3 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 EKX54747.1 - 2.8 6.6 12.2 4.4 6.0 12.2 1.3 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 EKX54747.1 - 5 6.0 5.3 6.3 5.7 5.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 PPL5 PF18168.1 EKX54747.1 - 8.1 5.6 12.3 12 5.1 12.3 1.3 1 0 0 1 1 1 0 Prim-pol family 5 EF-hand_1 PF00036.32 EKX54748.1 - 5.4e-12 44.4 1.9 2.5e-05 23.5 0.1 2.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EKX54748.1 - 7.5e-11 41.1 0.0 9.9e-05 22.0 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EKX54748.1 - 8.9e-11 40.8 0.0 6.5e-05 22.2 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX54748.1 - 1.7e-10 41.2 0.0 2.9e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EKX54748.1 - 5.8e-07 29.3 0.7 1e-05 25.2 0.2 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 EKX54748.1 - 0.002 18.1 0.0 0.0054 16.7 0.0 1.6 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Asp-B-Hydro_N PF05279.11 EKX54748.1 - 0.089 12.8 0.4 0.16 12.0 0.4 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region EF-hand_1 PF00036.32 EKX54749.1 - 7.1e-12 44.0 0.1 2.8e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EKX54749.1 - 6.8e-11 42.5 0.0 1.2e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX54749.1 - 3.2e-10 39.0 0.2 8.4e-05 21.9 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EKX54749.1 - 1.3e-09 37.2 3.0 1.1e-05 24.9 0.0 2.8 1 1 1 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EKX54749.1 - 8.8e-06 25.5 0.0 0.024 14.5 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 EKX54749.1 - 0.19 11.7 0.0 0.4 10.6 0.0 1.5 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand FKBP_C PF00254.28 EKX54750.1 - 2.9e-35 120.5 0.1 1.3e-30 105.5 0.0 3.9 4 0 0 4 4 4 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 EKX54750.1 - 1.2e-11 43.9 4.6 0.0018 18.0 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX54750.1 - 2.5e-05 23.9 2.3 0.11 12.2 0.1 3.5 2 1 1 3 3 3 1 TPR repeat TPR_2 PF07719.17 EKX54750.1 - 4.5e-05 23.2 16.5 0.0013 18.6 0.7 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EKX54750.1 - 0.00011 22.7 6.5 0.042 14.5 0.6 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX54750.1 - 0.00012 22.6 2.6 0.00012 22.6 2.6 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat FKBP_N_2 PF18023.1 EKX54750.1 - 0.00077 19.5 0.1 2.7 8.1 0.1 3.7 3 1 1 4 4 3 1 BDBT FKBP like N-terminal TPR_9 PF13371.6 EKX54750.1 - 0.0031 17.6 2.3 0.0084 16.2 2.3 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX54750.1 - 0.0041 17.2 8.6 0.089 13.1 0.1 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX54750.1 - 0.0048 17.4 6.7 0.021 15.3 5.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX54750.1 - 0.018 15.1 2.6 0.16 12.1 0.3 3.2 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 EKX54750.1 - 0.053 14.2 0.6 0.053 14.2 0.6 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat CotJB PF12652.7 EKX54750.1 - 0.14 12.4 0.0 0.77 10.0 0.0 2.3 1 1 1 2 2 2 0 CotJB protein TPR_7 PF13176.6 EKX54750.1 - 0.28 11.3 3.2 4.9 7.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat NT-C2 PF10358.9 EKX54751.1 - 4.3e-05 23.3 0.1 9.1e-05 22.2 0.1 1.6 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF155 PF02582.14 EKX54751.1 - 0.013 15.6 4.1 0.023 14.8 4.1 1.5 1 0 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.6 EKX54751.1 - 1.7 9.2 9.6 37 4.9 0.5 3.9 3 1 0 3 3 3 0 Uncharacterised protein family UPF0449 DnaJ_CXXCXGXG PF00684.19 EKX54753.1 - 5.2e-06 26.7 99.7 0.22 11.9 23.0 5.5 1 1 3 4 4 4 3 DnaJ central domain DUF4812 PF16071.5 EKX54753.1 - 0.26 11.1 0.0 26 4.7 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4812) Serinc PF03348.15 EKX54755.1 - 4.3e-78 263.2 16.2 5.2e-78 262.9 16.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF2101 PF09874.9 EKX54755.1 - 2.5 7.7 6.8 0.41 10.3 2.3 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) AhpC-TSA PF00578.21 EKX54757.1 - 9.8e-07 28.7 0.0 1.1e-06 28.5 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EKX54757.1 - 4.5e-06 26.5 0.0 4.6e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin DUF1057 PF06342.12 EKX54757.1 - 0.12 11.3 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) AhpC-TSA_2 PF13911.6 EKX54757.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme DSPc PF00782.20 EKX54758.1 - 3e-23 82.1 0.0 3.6e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EKX54758.1 - 0.0016 18.7 0.1 0.0032 17.7 0.0 1.5 1 1 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 EKX54758.1 - 0.094 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Dimer_Tnp_Tn5 PF02281.16 EKX54758.1 - 0.13 11.9 0.0 0.33 10.7 0.0 1.6 1 1 1 2 2 2 0 Transposase Tn5 dimerisation domain DUF777 PF05606.11 EKX54758.1 - 0.14 11.9 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF777) RWP-RK PF02042.15 EKX54759.1 - 6.9e-13 48.3 0.0 1.4e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain DUF4452 PF14618.6 EKX54759.1 - 1.3 8.9 5.7 2.1 8.2 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) RWP-RK PF02042.15 EKX54761.1 - 6e-13 48.5 0.1 1.4e-12 47.4 0.0 1.7 2 0 0 2 2 2 1 RWP-RK domain DUF4452 PF14618.6 EKX54761.1 - 1.2 9.0 4.9 1.9 8.3 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) RWP-RK PF02042.15 EKX54763.1 - 6e-13 48.5 0.1 1.4e-12 47.4 0.0 1.7 2 0 0 2 2 2 1 RWP-RK domain DUF4452 PF14618.6 EKX54763.1 - 1.2 9.0 4.9 1.9 8.3 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) RWP-RK PF02042.15 EKX54765.1 - 6e-13 48.5 0.1 1.4e-12 47.4 0.0 1.7 2 0 0 2 2 2 1 RWP-RK domain DUF4452 PF14618.6 EKX54765.1 - 1.2 9.0 4.9 1.9 8.3 4.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) RWP-RK PF02042.15 EKX54767.1 - 5.9e-13 48.6 0.1 1.4e-12 47.4 0.0 1.7 2 0 0 2 2 2 1 RWP-RK domain DUF4452 PF14618.6 EKX54767.1 - 0.85 9.5 5.1 1.4 8.8 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) RWP-RK PF02042.15 EKX54769.1 - 3.1e-13 49.5 0.1 7.6e-13 48.2 0.0 1.7 2 0 0 2 2 2 1 RWP-RK domain RWP-RK PF02042.15 EKX54770.1 - 5.6e-13 48.6 0.0 1.1e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain LrgB PF04172.16 EKX54771.1 - 4.6e-37 127.6 15.3 4.6e-37 127.6 15.3 2.3 2 1 0 2 2 2 1 LrgB-like family LrgA PF03788.14 EKX54771.1 - 0.00043 20.2 4.5 0.00043 20.2 4.5 3.9 3 0 0 3 3 3 1 LrgA family DUF1467 PF07330.12 EKX54771.1 - 0.53 10.3 3.3 0.77 9.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1467) F_actin_cap_B PF01115.17 EKX54772.1 - 3e-91 305.3 0.0 3.4e-91 305.1 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Cupin_8 PF13621.6 EKX54773.1 - 3e-07 30.4 0.7 5e-07 29.7 0.1 1.8 2 1 0 2 2 2 1 Cupin-like domain DUF4820 PF16091.5 EKX54773.1 - 0.12 11.7 3.1 0.31 10.4 3.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) FAM176 PF14851.6 EKX54773.1 - 0.13 11.9 12.4 0.1 12.3 8.6 2.2 2 0 0 2 2 2 0 FAM176 family V_ATPase_I PF01496.19 EKX54773.1 - 0.15 10.0 0.7 0.24 9.3 0.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RNA_pol_3_Rpc31 PF11705.8 EKX54773.1 - 0.17 12.1 17.4 0.055 13.7 11.6 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Astro_capsid_p PF12226.8 EKX54773.1 - 0.37 9.9 7.4 0.69 9.0 7.4 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF913 PF06025.12 EKX54773.1 - 0.49 9.3 2.0 0.97 8.3 2.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Nucleo_P87 PF07267.11 EKX54773.1 - 0.51 9.1 5.5 0.89 8.3 5.5 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CPSF100_C PF13299.6 EKX54773.1 - 1.7 8.8 7.3 5.1 7.3 3.1 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF2457 PF10446.9 EKX54773.1 - 2.2 7.4 18.6 0.4 9.8 14.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) RNA_pol_Rpc4 PF05132.14 EKX54773.1 - 2.7 8.4 8.4 0.23 11.9 2.8 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 PPP4R2 PF09184.11 EKX54773.1 - 2.9 7.4 14.5 0.81 9.2 10.2 1.9 2 0 0 2 2 2 0 PPP4R2 TRAP_alpha PF03896.16 EKX54773.1 - 3.4 6.8 6.9 6.8 5.8 6.9 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RRN3 PF05327.11 EKX54773.1 - 4.2 5.8 6.0 7.1 5.0 6.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 EKX54773.1 - 4.7 5.2 16.8 8.5 4.3 16.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi Vfa1 PF08432.10 EKX54773.1 - 4.8 7.5 15.2 0.61 10.4 8.9 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Afi1 PF07792.12 EKX54773.1 - 5.7 7.4 11.4 0.62 10.5 6.1 2.0 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PBP1_TM PF14812.6 EKX54773.1 - 6.8 7.1 15.0 2.2 8.7 11.5 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TFB6 PF17110.5 EKX54773.1 - 9.1 6.0 7.9 27 4.5 7.9 1.7 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Pox_Ag35 PF03286.14 EKX54773.1 - 9.9 5.9 18.6 0.022 14.6 7.4 2.1 2 1 0 2 2 2 0 Pox virus Ag35 surface protein Cupin_8 PF13621.6 EKX54774.1 - 1e-18 68.0 0.0 1.3e-18 67.7 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 EKX54774.1 - 3.1e-05 23.6 0.0 7.2e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 Cupin domain Cupin_4 PF08007.12 EKX54774.1 - 0.00024 20.7 0.0 0.00025 20.6 0.0 1.4 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 EKX54774.1 - 0.0016 18.9 0.0 0.0017 18.8 0.0 1.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase MORN PF02493.20 EKX54775.1 - 4.9e-31 104.8 25.8 1.4e-07 31.0 0.1 5.8 5 1 1 6 6 6 6 MORN repeat Pkinase PF00069.25 EKX54776.1 - 1.9e-60 204.5 0.0 2.2e-60 204.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX54776.1 - 2e-33 115.8 0.0 2.3e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX54776.1 - 8.5e-05 21.5 0.0 0.0029 16.4 0.0 2.0 1 1 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EKX54776.1 - 0.00022 20.7 0.0 0.00043 19.7 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EKX54776.1 - 0.0015 18.0 0.1 0.0019 17.6 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EKX54776.1 - 0.0043 16.1 0.1 0.018 14.0 0.1 1.9 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EKX54776.1 - 0.068 12.8 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 EKX54776.1 - 0.075 12.1 2.4 0.18 10.8 2.4 1.7 1 1 0 1 1 1 0 Seadornavirus VP7 TPR_8 PF13181.6 EKX54776.1 - 0.15 12.4 0.0 0.63 10.4 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat APH PF01636.23 EKX54776.1 - 0.25 11.2 0.2 0.58 10.0 0.3 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family C2 PF00168.30 EKX54777.1 - 6.5e-08 32.8 0.0 1.5e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain PDZ_6 PF17820.1 EKX54777.1 - 3.8e-06 26.6 0.0 9.2e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX54777.1 - 2.1e-05 24.8 0.0 4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX54777.1 - 0.063 13.6 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 PDZ domain DUF4231 PF14015.6 EKX54777.1 - 0.14 12.6 0.1 0.14 12.6 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) CLLAC PF15675.5 EKX54777.1 - 9.7 5.9 8.9 0.52 9.9 0.6 3.0 3 0 0 3 3 3 0 CLLAC-motif containing domain LRR_6 PF13516.6 EKX54778.1 - 1.1e-13 50.0 0.4 0.00083 19.2 0.0 4.6 4 0 0 4 4 4 3 Leucine Rich repeat LRR_8 PF13855.6 EKX54778.1 - 1e-08 34.8 0.2 1.6e-06 27.8 0.2 3.3 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 EKX54778.1 - 1.6e-06 28.4 0.4 0.0048 17.3 0.2 3.6 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX54778.1 - 0.0012 19.1 0.6 61 4.8 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich Repeat Mito_carr PF00153.27 EKX54780.1 - 2.1e-56 187.8 6.1 1.2e-23 82.9 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein PIG-P PF08510.12 EKX54781.1 - 3.8e-32 110.8 7.1 4.3e-32 110.6 7.1 1.0 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 EKX54781.1 - 0.41 11.0 11.1 0.97 9.8 9.7 2.0 1 1 1 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PBP PF01161.20 EKX54782.1 - 3.4e-24 85.7 0.0 8.7e-24 84.3 0.0 1.6 2 0 0 2 2 2 1 Phosphatidylethanolamine-binding protein Ank_2 PF12796.7 EKX54783.1 - 4e-07 30.5 0.1 5.4e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX54783.1 - 4.2e-07 30.1 0.1 7.1e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX54783.1 - 2.1e-06 28.1 0.7 7.4e-05 23.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX54783.1 - 2.8e-05 24.1 0.6 0.11 13.1 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EKX54783.1 - 0.00097 19.5 0.6 0.11 13.0 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeat Wzz PF02706.15 EKX54783.1 - 0.038 14.3 0.0 0.072 13.4 0.0 1.4 1 0 0 1 1 1 0 Chain length determinant protein HCNGP PF07818.13 EKX54784.1 - 1e-19 71.0 0.2 2.6e-19 69.7 0.1 1.7 2 0 0 2 2 2 1 HCNGP-like protein CorA PF01544.18 EKX54785.1 - 1.6e-22 80.1 1.7 1.7e-20 73.5 0.4 2.6 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein CRAL_TRIO PF00650.20 EKX54787.1 - 1.1e-14 54.5 0.0 1.2e-14 54.4 0.0 1.0 1 0 0 1 1 1 1 CRAL/TRIO domain Neuregulin PF02158.15 EKX54787.1 - 0.25 10.6 0.0 0.31 10.4 0.0 1.0 1 0 0 1 1 1 0 Neuregulin intracellular region Fez1 PF06818.15 EKX54789.1 - 0.00083 19.9 15.0 0.00083 19.9 15.0 7.2 3 3 4 7 7 7 4 Fez1 ATP-synt_ab_N PF02874.23 EKX54789.1 - 0.035 14.6 0.1 7.2 7.2 0.0 2.9 2 0 0 2 2 2 0 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_E_2 PF08112.11 EKX54789.1 - 3.3 8.0 8.7 1.6 9.1 0.2 4.4 4 0 0 4 4 4 0 ATP synthase epsilon subunit HCV_NS4b PF01001.19 EKX54791.1 - 0.0024 17.5 0.1 0.0044 16.6 0.1 1.3 1 0 0 1 1 1 1 Hepatitis C virus non-structural protein NS4b HAMP_N3 PF18575.1 EKX54791.1 - 0.17 11.5 0.0 3.7 7.2 0.0 2.3 2 0 0 2 2 2 0 HAMP N-terminal domain 3 DUF4519 PF15012.6 EKX54791.1 - 1.9 8.7 4.4 5.1 7.4 4.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Peptidase_C69 PF03577.15 EKX54792.1 - 2e-50 171.9 0.0 1.3e-49 169.3 0.0 1.9 1 1 0 1 1 1 1 Peptidase family C69 Frag1 PF10277.9 EKX54793.1 - 3.7e-15 56.1 13.0 3.7e-15 56.1 13.0 1.9 2 0 0 2 2 2 1 Frag1/DRAM/Sfk1 family Tom5 PF10642.9 EKX54793.1 - 0.017 15.1 0.1 0.068 13.2 0.1 2.0 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase U-box PF04564.15 EKX54794.1 - 2.9e-14 53.0 0.0 3.3e-14 52.8 0.0 1.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EKX54794.1 - 1.4e-06 28.0 0.1 2.1e-06 27.5 0.1 1.5 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EKX54794.1 - 0.0002 21.3 0.0 0.00039 20.4 0.0 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EKX54794.1 - 0.06 13.2 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 EKX54794.1 - 0.069 12.5 0.0 0.076 12.4 0.0 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Stathmin PF00836.19 EKX54795.1 - 0.59 10.1 7.5 0.14 12.2 2.6 2.3 2 0 0 2 2 2 0 Stathmin family CENP-H PF05837.12 EKX54795.1 - 1.4 9.3 11.1 0.13 12.7 4.8 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) YabA PF06156.13 EKX54795.1 - 2.3 8.9 10.0 1.6 9.4 4.7 2.7 2 0 0 2 2 2 0 Initiation control protein YabA SAS-6_N PF16531.5 EKX54796.1 - 1.1e-28 99.6 2.3 2.1e-28 98.8 2.3 1.5 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal Methyltransf_25 PF13649.6 EKX54797.1 - 7.4e-15 55.4 0.2 9.6e-13 48.7 0.1 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX54797.1 - 1.4e-14 54.3 0.0 2.1e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX54797.1 - 1.1e-11 45.2 0.6 1.2e-10 41.9 0.2 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX54797.1 - 7.8e-10 39.4 0.0 1.4e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX54797.1 - 1.6e-07 31.2 0.1 2.4e-07 30.7 0.1 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EKX54797.1 - 0.00025 20.6 0.0 0.00041 19.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase DUF938 PF06080.12 EKX54797.1 - 0.015 15.1 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_17 PF12692.7 EKX54797.1 - 0.097 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase DnaJ PF00226.31 EKX54798.1 - 7.3e-20 70.9 1.1 8.4e-20 70.7 1.1 1.1 1 0 0 1 1 1 1 DnaJ domain Sel1 PF08238.12 EKX54800.1 - 6.6e-30 102.9 36.0 9.5e-05 22.9 0.1 14.5 15 0 0 15 15 15 8 Sel1 repeat TPR_8 PF13181.6 EKX54800.1 - 0.0035 17.4 0.8 0.11 12.7 0.0 4.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX54800.1 - 0.028 15.1 18.9 0.15 12.8 0.0 7.3 9 1 0 9 9 9 0 Tetratricopeptide repeat Herpes_IE68 PF02479.16 EKX54800.1 - 0.071 12.7 0.3 0.22 11.1 0.3 1.8 1 0 0 1 1 1 0 Herpesvirus immediate early protein PUL PF08324.11 EKX54800.1 - 0.11 11.7 0.8 3 7.0 0.1 2.8 3 0 0 3 3 3 0 PUL domain TPR_17 PF13431.6 EKX54800.1 - 0.17 12.3 2.0 23 5.7 0.0 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EKX54800.1 - 0.24 11.6 14.2 0.22 11.7 0.2 6.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX54800.1 - 0.65 11.0 0.1 0.65 11.0 0.1 7.9 7 2 1 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 EKX54800.1 - 1.6 8.7 7.8 1.8 8.6 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EKX54800.1 - 3.9 7.9 9.8 29 5.1 0.1 4.8 4 2 1 5 5 5 0 Alkyl sulfatase dimerisation NUC153 PF08159.12 EKX54801.1 - 1.7e-10 40.5 7.5 4.3e-10 39.2 0.3 3.7 3 0 0 3 3 3 2 NUC153 domain ANAPC4_WD40 PF12894.7 EKX54802.1 - 1.2e-08 35.1 0.9 3 8.2 0.1 6.4 3 3 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EKX54802.1 - 5.5e-07 30.2 8.2 1.5 9.8 0.0 6.7 6 1 1 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.11 EKX54802.1 - 1.2e-06 28.6 0.6 1.6 8.6 0.0 5.1 2 2 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EKX54802.1 - 0.11 12.5 0.2 15 5.7 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Lactonase PF10282.9 EKX54802.1 - 0.18 11.0 0.0 6.4 5.9 0.0 2.3 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller Polyketide_cyc2 PF10604.9 EKX54803.1 - 5.3e-07 30.0 0.0 1.2e-06 28.9 0.0 1.5 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EKX54803.1 - 2.4e-05 24.5 0.0 4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport adh_short PF00106.25 EKX54806.1 - 2.7e-08 33.5 0.0 0.0013 18.2 0.0 2.5 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 EKX54806.1 - 0.0014 18.3 0.0 0.21 11.1 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase SnAC PF14619.6 EKX54807.1 - 0.028 15.0 0.4 0.071 13.7 0.4 1.7 1 0 0 1 1 1 0 Snf2-ATP coupling, chromatin remodelling complex zf-MYND PF01753.18 EKX54808.1 - 5.6e-05 23.2 16.1 5.6e-05 23.2 16.1 2.8 3 0 0 3 3 3 1 MYND finger F-box-like PF12937.7 EKX54808.1 - 0.058 13.3 0.0 0.23 11.4 0.0 2.1 1 1 0 1 1 1 0 F-box-like Sel1 PF08238.12 EKX54808.1 - 0.18 12.5 3.1 1.7 9.4 3.1 2.4 1 1 0 1 1 1 0 Sel1 repeat SUIM_assoc PF16619.5 EKX54808.1 - 0.61 10.2 9.8 1.9 8.6 9.8 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 FlxA PF14282.6 EKX54809.1 - 0.037 14.0 4.5 1.4 9.0 0.3 2.4 2 0 0 2 2 2 0 FlxA-like protein SKA2 PF16740.5 EKX54809.1 - 0.16 11.8 8.3 1.3 8.9 3.1 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 ATP-synt_D PF01813.17 EKX54809.1 - 6 6.7 9.7 79 3.0 9.7 2.1 1 1 0 1 1 1 0 ATP synthase subunit D Spc24 PF08286.11 EKX54809.1 - 7.3 6.9 7.6 4.9 7.4 1.4 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Presenilin PF01080.17 EKX54809.1 - 8.8 5.0 7.7 12 4.6 7.7 1.1 1 0 0 1 1 1 0 Presenilin SET PF00856.28 EKX54810.1 - 1.6e-05 25.4 2.6 3.7e-05 24.2 0.0 2.7 3 1 0 3 3 3 1 SET domain Kinesin PF00225.23 EKX54811.1 - 5e-80 268.9 0.2 5.8e-80 268.7 0.2 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EKX54811.1 - 7.1e-34 116.9 0.0 1e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 Microtubule binding DUF2181 PF10223.9 EKX54811.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2181) Ank_5 PF13857.6 EKX54812.1 - 5.8e-10 39.2 0.0 6.4e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX54812.1 - 6.6e-06 26.1 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 EKX54812.1 - 4.8e-05 23.8 0.0 6.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX54812.1 - 7.2e-05 23.1 0.0 0.00027 21.3 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 EKX54812.1 - 0.0001 22.8 0.0 0.00011 22.7 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) LysM PF01476.20 EKX54812.1 - 0.099 12.7 0.0 0.14 12.2 0.0 1.4 1 1 0 1 1 1 0 LysM domain DCP1 PF06058.13 EKX54812.1 - 0.13 12.2 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Dcp1-like decapping family F420_oxidored PF03807.17 EKX54813.1 - 7.1e-13 49.0 0.0 1.3e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EKX54813.1 - 5.2e-05 22.7 0.0 8.8e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain C2 PF00168.30 EKX54813.1 - 0.00011 22.4 0.0 0.00035 20.8 0.0 1.9 2 0 0 2 2 2 1 C2 domain GFO_IDH_MocA PF01408.22 EKX54813.1 - 0.00021 22.1 0.0 0.00039 21.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ApbA PF02558.16 EKX54813.1 - 0.00029 20.5 0.1 0.0071 16.0 0.0 2.6 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 EKX54813.1 - 0.00082 19.6 0.0 0.0016 18.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Rossmann-like PF10727.9 EKX54813.1 - 0.0016 18.3 0.2 0.0029 17.5 0.2 1.3 1 0 0 1 1 1 1 Rossmann-like domain PDH PF02153.17 EKX54813.1 - 0.0046 16.0 0.0 0.0074 15.3 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase Sacchrp_dh_NADP PF03435.18 EKX54813.1 - 0.016 15.4 0.0 0.037 14.3 0.0 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 EKX54813.1 - 0.042 13.8 0.0 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Tropomyosin_1 PF12718.7 EKX54814.1 - 0.089 12.9 14.8 0.19 11.9 14.8 1.5 1 0 0 1 1 1 0 Tropomyosin like FOXP-CC PF16159.5 EKX54814.1 - 0.93 10.2 8.2 10 6.8 0.3 2.9 2 0 0 2 2 2 0 FOXP coiled-coil domain Ion_trans PF00520.31 EKX54815.1 - 3.7e-11 42.7 6.4 4.8e-11 42.3 6.4 1.0 1 0 0 1 1 1 1 Ion transport protein GAPT PF11770.8 EKX54815.1 - 0.024 14.5 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) zf-C2H2 PF00096.26 EKX54816.1 - 4.7e-05 23.6 7.2 0.08 13.4 0.0 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EKX54816.1 - 0.0015 18.8 5.8 0.76 10.1 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EKX54816.1 - 0.002 18.8 7.2 0.67 11.0 4.1 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger DUF3161 PF11362.8 EKX54816.1 - 0.0086 16.0 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3161) Arc_trans_TRASH PF08394.10 EKX54816.1 - 0.023 15.0 0.1 0.038 14.3 0.1 1.3 1 0 0 1 1 1 0 Archaeal TRASH domain zf-met PF12874.7 EKX54816.1 - 0.07 13.6 3.1 0.07 13.6 3.1 2.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EKX54816.1 - 0.089 12.8 4.9 0.13 12.3 4.9 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger DUF629 PF04780.12 EKX54816.1 - 0.24 9.9 1.5 0.27 9.7 1.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-RING_2 PF13639.6 EKX54819.1 - 7.5e-17 61.4 6.1 8.3e-17 61.3 6.1 1.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX54819.1 - 1.8e-12 46.9 6.6 2.1e-12 46.7 6.6 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EKX54819.1 - 3.9e-11 42.5 4.9 6.4e-11 41.8 4.9 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EKX54819.1 - 1.6e-10 41.1 9.1 1.3e-09 38.2 9.1 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EKX54819.1 - 5.5e-10 38.9 5.1 6.5e-10 38.7 5.1 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EKX54819.1 - 8.8e-09 35.2 3.9 9.8e-09 35.0 3.9 1.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EKX54819.1 - 9.7e-09 35.1 5.5 1.3e-08 34.8 5.5 1.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EKX54819.1 - 9.6e-07 28.6 2.3 1.1e-06 28.4 2.3 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX54819.1 - 1.8e-06 27.7 2.3 2.5e-06 27.2 2.3 1.3 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EKX54819.1 - 1.2e-05 25.2 4.2 1.9e-05 24.6 4.2 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EKX54819.1 - 0.00012 21.7 3.5 0.00016 21.2 3.5 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 EKX54819.1 - 0.00012 22.1 4.0 0.00026 21.1 4.0 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 EKX54819.1 - 0.00031 20.6 2.8 0.0094 15.9 0.6 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-Nse PF11789.8 EKX54819.1 - 0.00045 20.0 2.3 0.00051 19.8 2.3 1.1 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 EKX54819.1 - 0.00072 19.7 5.6 0.0029 17.8 5.6 2.0 1 1 0 1 1 1 1 FANCL C-terminal domain PHD PF00628.29 EKX54819.1 - 0.0013 18.6 4.0 0.0019 18.0 4.0 1.3 1 1 0 1 1 1 1 PHD-finger RINGv PF12906.7 EKX54819.1 - 0.0018 18.4 4.2 0.0046 17.1 4.2 1.7 1 1 0 1 1 1 1 RING-variant domain zf-P11 PF03854.14 EKX54819.1 - 0.011 15.4 5.6 0.022 14.4 5.6 1.5 1 1 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.6 EKX54819.1 - 0.012 15.3 3.8 0.016 15.0 3.8 1.1 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.14 EKX54819.1 - 0.015 15.1 0.3 0.04 13.8 0.1 1.8 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING-like PF08746.11 EKX54819.1 - 0.046 14.0 3.5 0.068 13.5 3.5 1.3 1 1 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.5 EKX54819.1 - 0.08 13.0 4.7 0.2 11.7 4.7 1.8 1 1 0 1 1 1 0 Zinc-finger PHD_3 PF13922.6 EKX54819.1 - 0.22 11.9 3.0 0.25 11.7 3.0 1.4 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx UBZ_FAAP20 PF15750.5 EKX54819.1 - 1.2 9.1 6.6 4.6 7.3 0.2 2.4 3 0 0 3 3 2 0 Ubiquitin-binding zinc-finger MORN PF02493.20 EKX54821.1 - 6.5e-33 110.7 69.1 5e-05 23.0 0.8 12.5 12 1 0 12 12 12 11 MORN repeat Arm PF00514.23 EKX54822.1 - 4e-24 83.8 6.0 0.0047 16.9 0.0 8.1 8 0 0 8 8 8 6 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EKX54822.1 - 9.1e-11 41.7 0.3 0.69 10.0 0.0 6.3 1 1 7 8 8 8 3 Spinocerebellar ataxia type 10 protein domain DUF1456 PF07308.13 EKX54822.1 - 9.6e-07 29.1 8.1 6.1 7.3 0.0 7.3 8 0 0 8 8 8 1 Protein of unknown function (DUF1456) HEAT_EZ PF13513.6 EKX54822.1 - 5.6e-06 26.7 3.1 0.046 14.2 0.1 5.4 3 2 4 7 7 7 2 HEAT-like repeat Hom_end PF05204.14 EKX54822.1 - 6.1e-05 23.1 0.0 69 3.7 0.0 6.5 2 2 6 8 8 8 0 Homing endonuclease Mto2_bdg PF12808.7 EKX54822.1 - 0.002 18.4 3.0 4.7e+02 1.2 0.0 7.0 8 0 0 8 8 8 0 Micro-tubular organiser Mto1 C-term Mto2-binding region GAD PF02938.14 EKX54822.1 - 0.0046 17.2 3.8 27 5.1 0.1 4.9 2 2 5 7 7 7 0 GAD domain DXP_synthase_N PF13292.6 EKX54822.1 - 0.0052 16.0 1.1 11 5.1 0.0 4.3 1 1 2 5 5 5 1 1-deoxy-D-xylulose-5-phosphate synthase SBP_bac_8 PF13416.6 EKX54822.1 - 0.026 14.3 0.0 12 5.6 0.0 3.8 1 1 3 5 5 5 0 Bacterial extracellular solute-binding protein DUF4920 PF16267.5 EKX54822.1 - 0.056 13.4 3.5 34 4.5 0.0 4.9 6 0 0 6 6 6 0 Domain of unknown function (DUF4920) TPR_15 PF13429.6 EKX54822.1 - 0.13 11.5 0.0 93 2.1 0.0 3.7 2 1 2 4 4 4 0 Tetratricopeptide repeat PUL PF08324.11 EKX54822.1 - 0.35 10.1 1.8 1.2 8.3 0.5 2.6 1 1 0 2 2 2 0 PUL domain Flt3_lig PF02947.14 EKX54822.1 - 0.42 10.8 7.1 1.1e+02 2.9 0.0 5.5 1 1 6 7 7 7 0 flt3 ligand ART PF01129.18 EKX54823.1 - 0.013 14.8 0.0 0.014 14.7 0.0 1.1 1 0 0 1 1 1 0 NAD:arginine ADP-ribosyltransferase PB1 PF00564.24 EKX54824.1 - 4.9e-07 29.6 0.0 9.9e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 PB1 domain HTH_Tnp_Tc5 PF03221.16 EKX54824.1 - 5.4e-07 29.5 0.0 1.2e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 EKX54824.1 - 7.5e-05 22.3 0.7 0.00016 21.2 0.7 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_3 PF01381.22 EKX54824.1 - 0.00072 19.6 0.1 0.0025 17.8 0.1 2.0 1 0 0 1 1 1 1 Helix-turn-helix HTH_Crp_2 PF13545.6 EKX54824.1 - 0.03 14.3 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Sigma70_r4 PF04545.16 EKX54824.1 - 0.052 13.1 0.1 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_38 PF13936.6 EKX54824.1 - 0.063 13.1 0.3 1.1 9.1 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_23 PF13384.6 EKX54824.1 - 0.15 11.9 0.0 0.53 10.1 0.0 2.0 1 0 0 1 1 1 0 Homeodomain-like domain Cro PF09048.10 EKX54824.1 - 0.15 12.1 0.1 0.61 10.2 0.1 2.0 2 0 0 2 2 2 0 Cro BRCT PF00533.26 EKX54825.1 - 2.8e-12 46.8 0.0 6.5e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 EKX54825.1 - 3.9e-12 46.7 0.0 1.6e-11 44.8 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EKX54825.1 - 3.3e-07 30.6 0.0 1.9e-06 28.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EKX54825.1 - 5.6e-06 26.2 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 EKX54825.1 - 6.4e-05 22.9 0.0 0.00018 21.5 0.0 1.7 2 0 0 2 2 1 1 Rad17 P-loop domain AAA_5 PF07728.14 EKX54825.1 - 0.00016 21.7 0.0 0.00043 20.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EKX54825.1 - 0.00019 21.2 0.1 0.14 11.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_assoc_2 PF16193.5 EKX54825.1 - 0.00038 20.7 0.0 0.001 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain BRCT_2 PF16589.5 EKX54825.1 - 0.0011 19.3 0.0 0.0026 18.1 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RFC1 PF08519.12 EKX54825.1 - 0.0016 18.6 0.0 0.0045 17.2 0.0 1.7 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain PTCB-BRCT PF12738.7 EKX54825.1 - 0.0018 18.2 2.4 0.0056 16.6 0.2 2.4 2 0 0 2 2 2 1 twin BRCT domain Sigma54_activ_2 PF14532.6 EKX54825.1 - 0.0051 16.9 0.0 0.044 13.9 0.0 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_2 PF07724.14 EKX54825.1 - 0.0063 16.7 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EKX54825.1 - 0.0063 16.7 0.0 0.021 15.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.6 EKX54825.1 - 0.0089 15.8 1.7 0.91 9.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EKX54825.1 - 0.014 16.0 0.0 0.056 14.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EKX54825.1 - 0.015 15.4 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EKX54825.1 - 0.02 14.4 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 EKX54825.1 - 0.022 14.7 0.0 0.065 13.1 0.0 1.8 2 0 0 2 2 1 0 NTPase Zeta_toxin PF06414.12 EKX54825.1 - 0.024 13.9 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.17 EKX54825.1 - 0.036 13.2 0.0 0.16 11.0 0.0 2.0 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_16 PF13191.6 EKX54825.1 - 0.037 14.4 1.7 0.22 11.9 0.0 2.8 2 1 1 3 3 2 0 AAA ATPase domain Mg_chelatase PF01078.21 EKX54825.1 - 0.038 13.4 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EKX54825.1 - 0.053 13.4 0.1 5.2 7.0 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_3 PF07726.11 EKX54825.1 - 0.057 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EKX54825.1 - 0.11 12.2 0.0 0.58 9.9 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein ketoacyl-synt PF00109.26 EKX54826.1 - 5.9e-56 189.9 3.6 8.6e-56 189.3 3.6 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EKX54826.1 - 3.6e-37 127.0 1.0 9.7e-37 125.6 1.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EKX54826.1 - 7.9e-08 32.0 2.0 0.00096 18.6 0.6 2.8 2 1 1 3 3 3 2 Thiolase, N-terminal domain DUF5375 PF17345.2 EKX54826.1 - 0.088 12.7 0.1 0.78 9.6 0.1 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5375) EamA PF00892.20 EKX54827.1 - 1.2e-21 77.3 18.1 8.9e-13 48.6 4.0 2.4 2 0 0 2 2 2 2 EamA-like transporter family Pkinase PF00069.25 EKX54828.1 - 2.6e-46 158.1 0.0 3e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX54828.1 - 4.1e-45 154.1 0.0 4.6e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX54828.1 - 0.00038 19.4 0.0 0.00048 19.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX54828.1 - 0.0045 17.0 0.0 0.015 15.3 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family PDZ_6 PF17820.1 EKX54830.1 - 5.7e-06 26.1 0.1 1.1e-05 25.2 0.1 1.5 1 1 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX54830.1 - 4.7e-05 23.7 0.3 5.4e-05 23.5 0.3 1.1 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX54830.1 - 7.6e-05 22.6 0.0 8.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Tricorn protease PDZ domain PDZ_2 PF13180.6 EKX54830.1 - 0.0015 18.8 0.0 0.0019 18.5 0.0 1.1 1 0 0 1 1 1 1 PDZ domain Borrelia_REV PF03978.13 EKX54830.1 - 0.2 11.6 0.0 0.24 11.3 0.0 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein GTP_EFTU PF00009.27 EKX54832.1 - 2e-36 125.3 0.0 1.1e-35 123.0 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EKX54832.1 - 1.7e-19 69.6 0.0 3.8e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 EKX54832.1 - 6.4e-09 35.6 0.1 1.5e-08 34.5 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 EKX54832.1 - 3.4e-08 33.8 0.3 2e-07 31.3 0.2 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EKX54832.1 - 0.075 13.1 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 EKX54832.1 - 0.11 11.9 0.0 0.28 10.6 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit CaMKII_AD PF08332.10 EKX54834.1 - 4.1e-30 104.6 0.0 4.9e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain SnoaL_3 PF13474.6 EKX54834.1 - 5.1e-09 36.4 0.0 6.4e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EKX54834.1 - 5.5e-09 36.4 0.0 6.4e-09 36.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 EKX54834.1 - 0.14 12.8 0.0 0.28 11.9 0.0 1.5 1 1 0 1 1 1 0 SnoaL-like domain UvrD-helicase PF00580.21 EKX54835.1 - 4.2e-48 164.5 0.0 1.7e-47 162.5 0.0 1.9 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 EKX54835.1 - 6.1e-37 127.8 0.0 1.7e-36 126.3 0.0 1.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EKX54835.1 - 9.8e-34 116.8 0.0 1.9e-33 115.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EKX54835.1 - 1.8e-06 27.9 4.3 0.093 12.5 0.3 4.1 3 1 1 4 4 4 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 EKX54835.1 - 2.3e-06 27.3 0.2 0.017 14.9 0.0 2.4 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 EKX54835.1 - 0.00021 21.1 0.0 0.024 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 EKX54835.1 - 0.019 14.8 0.0 0.19 11.4 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase Exonuc_V_gamma PF04257.14 EKX54835.1 - 0.029 12.6 0.1 0.066 11.4 0.0 1.6 2 0 0 2 2 2 0 Exodeoxyribonuclease V, gamma subunit AAA_22 PF13401.6 EKX54835.1 - 0.081 13.2 0.1 8.5 6.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 EKX54835.1 - 0.087 12.9 0.1 2.5 8.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain Terminase_6 PF03237.15 EKX54835.1 - 0.12 12.0 0.0 20 4.8 0.0 2.6 2 0 0 2 2 2 0 Terminase-like family Ribosomal_S14 PF00253.21 EKX54837.1 - 1.6e-08 34.1 2.0 2.1e-08 33.8 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Glyco_transf_22 PF03901.17 EKX54838.1 - 3e-64 217.8 15.9 9.7e-63 212.8 14.2 2.1 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family PMT_2 PF13231.6 EKX54838.1 - 6.8e-06 26.4 9.3 6.8e-06 26.4 9.3 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase RWP-RK PF02042.15 EKX54839.1 - 3.1e-13 49.5 0.1 5.2e-13 48.7 0.1 1.4 1 0 0 1 1 1 1 RWP-RK domain Preseq_ALAS PF09029.10 EKX54839.1 - 0.14 12.7 0.5 0.25 11.8 0.5 1.4 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence AAA_33 PF13671.6 EKX54840.1 - 4.6e-14 52.8 0.4 6.4e-11 42.6 0.4 2.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EKX54840.1 - 4.3e-05 24.1 0.0 0.00017 22.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 EKX54840.1 - 0.00048 19.7 0.0 0.00066 19.2 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.6 EKX54840.1 - 0.0014 19.0 0.1 0.1 13.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 EKX54840.1 - 0.0038 17.5 0.1 0.012 15.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EKX54840.1 - 0.0041 17.4 0.0 0.009 16.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EKX54840.1 - 0.037 14.4 0.0 0.054 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain tRNA_lig_kinase PF08303.11 EKX54840.1 - 0.038 14.1 0.0 0.07 13.2 0.0 1.4 1 1 0 1 1 1 0 tRNA ligase kinase domain Mg_chelatase PF01078.21 EKX54840.1 - 0.046 13.1 0.0 0.077 12.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MeaB PF03308.16 EKX54840.1 - 0.087 11.8 0.1 0.2 10.6 0.1 1.5 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 EKX54840.1 - 0.087 12.5 0.0 0.19 11.4 0.0 1.6 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase GTP_EFTU PF00009.27 EKX54840.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain CoaE PF01121.20 EKX54840.1 - 0.16 11.6 0.2 0.34 10.5 0.0 1.6 2 0 0 2 2 2 0 Dephospho-CoA kinase cobW PF02492.19 EKX54840.1 - 0.17 11.4 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Ank_4 PF13637.6 EKX54841.1 - 4.3e-19 68.6 1.3 3.1e-07 30.8 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX54841.1 - 6.7e-17 59.9 0.4 0.0033 17.8 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EKX54841.1 - 1.9e-15 56.5 0.7 5.4e-05 23.5 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 EKX54841.1 - 7.1e-15 55.4 0.5 0.00038 21.0 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EKX54841.1 - 2.8e-14 53.0 2.9 5.3e-06 26.6 0.5 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) FmiP_Thoc5 PF09766.9 EKX54842.1 - 7.4e-58 196.6 9.2 1.2e-57 195.9 9.2 1.3 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 ETC_C1_NDUFA4 PF04800.12 EKX54842.1 - 3e-25 88.3 0.1 7.6e-25 87.0 0.1 1.7 1 0 0 1 1 1 1 ETC complex I subunit conserved region RWD PF05773.22 EKX54842.1 - 0.00011 22.5 1.0 0.045 14.0 0.0 2.8 2 0 0 2 2 2 2 RWD domain PDEase_I PF00233.19 EKX54843.1 - 1.6e-67 227.7 0.0 1.9e-67 227.4 0.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF5519 PF17648.1 EKX54843.1 - 0.0064 16.3 0.4 0.013 15.3 0.4 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5519) TBD PF12845.7 EKX54843.1 - 0.084 12.8 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 TBD domain GWT1 PF06423.12 EKX54844.1 - 0.11 12.7 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 GWT1 Mid1 PF12929.7 EKX54845.1 - 7.4e-15 55.1 16.8 1.4e-14 54.1 16.8 1.4 1 1 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 EKX54845.1 - 1.4 9.5 17.0 0.72 10.5 4.8 2.8 2 2 0 2 2 2 0 Fz domain PDZ_6 PF17820.1 EKX54846.1 - 6.4e-09 35.5 0.1 1.9e-08 34.0 0.1 1.9 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX54846.1 - 7.2e-08 32.7 0.1 1.7e-07 31.5 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX54846.1 - 1.2e-05 25.5 0.0 2.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Galactosyl_T PF01762.21 EKX54848.1 - 4.8e-19 68.9 0.0 7.4e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Glyco_transf_10 PF00852.19 EKX54848.1 - 1.4e-09 37.9 0.0 1.5e-06 28.0 0.0 2.4 1 1 1 2 2 2 2 Glycosyltransferase family 10 (fucosyltransferase) C-term NNMT_PNMT_TEMT PF01234.17 EKX54848.1 - 0.13 11.4 0.1 0.22 10.7 0.1 1.3 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family CPP1-like PF11833.8 EKX54849.1 - 4.9e-13 49.2 0.1 8.8e-13 48.4 0.1 1.4 1 1 0 1 1 1 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Cation_efflux PF01545.21 EKX54850.1 - 5.8e-13 49.0 4.6 7.4e-13 48.7 4.6 1.1 1 0 0 1 1 1 1 Cation efflux family Caps_synth_CapC PF14102.6 EKX54850.1 - 3.1 8.2 6.8 1.2 9.6 3.4 2.0 2 1 0 2 2 2 0 Capsule biosynthesis CapC MCM PF00493.23 EKX54851.1 - 1.8e-90 302.0 0.1 2.5e-90 301.5 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 EKX54851.1 - 1.1e-27 96.2 3.5 1.2e-27 96.1 2.2 1.8 2 0 0 2 2 1 1 MCM AAA-lid domain MCM_OB PF17207.3 EKX54851.1 - 2.9e-25 88.5 1.6 6.6e-25 87.4 1.6 1.6 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 EKX54851.1 - 4.8e-10 39.2 0.6 2.6e-05 23.7 0.1 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EKX54851.1 - 6.1e-08 32.8 0.0 1.7e-07 31.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EKX54851.1 - 1.4e-05 25.0 0.0 3.7e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EKX54851.1 - 0.00095 18.9 0.7 0.004 16.9 0.2 2.2 2 1 0 2 2 2 1 Sigma-54 interaction domain DIT1_PvcA PF05141.12 EKX54851.1 - 0.0073 15.8 0.3 0.012 15.1 0.3 1.3 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein AAA PF00004.29 EKX54851.1 - 0.0086 16.5 0.3 0.034 14.6 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX54851.1 - 0.017 15.5 2.4 0.13 12.6 0.1 3.0 3 1 0 3 3 3 0 AAA ATPase domain NTPase_1 PF03266.15 EKX54851.1 - 0.026 14.4 2.0 0.36 10.7 0.1 2.9 3 0 0 3 3 3 0 NTPase AAA_22 PF13401.6 EKX54851.1 - 0.036 14.3 1.3 0.31 11.3 0.0 2.9 3 1 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EKX54851.1 - 0.043 13.2 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 EKX54851.1 - 0.083 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Phage_hub_GP28 PF11110.8 EKX54851.1 - 0.15 12.0 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Baseplate hub distal subunit Pkinase PF00069.25 EKX54852.1 - 2.2e-53 181.3 0.0 2.5e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX54852.1 - 2e-33 115.8 0.0 6.8e-33 114.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX54852.1 - 7.6e-06 25.4 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EKX54852.1 - 3.1e-05 22.9 0.0 4.4e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX54852.1 - 0.012 15.6 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF680 PF05079.12 EKX54854.1 - 0.089 13.5 0.0 0.15 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF680) H_PPase PF03030.16 EKX54855.1 - 6.5e-233 775.1 31.1 7.3e-233 774.9 31.1 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Pkinase PF00069.25 EKX54857.1 - 4.3e-27 95.1 0.0 5.4e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX54857.1 - 3.2e-16 59.4 0.0 6.6e-16 58.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX54857.1 - 9.6e-08 31.2 0.0 1.5e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EKX54857.1 - 3.2e-06 27.3 0.1 0.0011 19.0 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 EKX54857.1 - 0.012 15.0 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EKX54857.1 - 0.082 12.5 0.1 0.18 11.3 0.1 1.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase VPS53_C PF16854.5 EKX54857.1 - 0.16 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 53 C-terminus Ras PF00071.22 EKX54858.1 - 1.7e-62 209.8 0.0 2e-62 209.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EKX54858.1 - 9.2e-33 113.0 0.1 2.4e-32 111.6 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EKX54858.1 - 4e-12 45.9 0.0 5e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EKX54858.1 - 3.5e-05 23.9 0.0 5.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EKX54858.1 - 0.00054 19.9 0.1 0.22 11.4 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EKX54858.1 - 0.0012 18.2 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EKX54858.1 - 0.0027 17.3 0.0 0.013 15.1 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EKX54858.1 - 0.015 15.6 0.1 0.18 12.1 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EKX54858.1 - 0.06 13.1 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 EKX54858.1 - 0.071 12.3 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 PDZ_6 PF17820.1 EKX54859.1 - 1.2e-11 44.3 0.0 2.1e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX54859.1 - 1.2e-06 28.7 0.1 1.7e-06 28.3 0.1 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX54859.1 - 2.8e-06 27.6 0.0 4.1e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX54859.1 - 0.008 16.1 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Tricorn protease PDZ domain TraB PF01963.17 EKX54860.1 - 4.9e-14 52.9 1.0 1.1e-13 51.7 1.0 1.6 1 1 0 1 1 1 1 TraB family Glyoxalase_6 PF18029.1 EKX54862.1 - 0.01 16.6 0.0 0.21 12.4 0.0 2.4 1 1 0 1 1 1 0 Glyoxalase-like domain Glyoxalase PF00903.25 EKX54862.1 - 0.019 15.1 0.0 1.9 8.7 0.0 2.2 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EKX54862.1 - 0.082 13.2 0.0 26 5.1 0.0 2.5 2 1 0 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CAP_N PF01213.19 EKX54862.1 - 0.21 11.0 1.1 0.33 10.4 1.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TUSC2 PF15000.6 EKX54863.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Tumour suppressor candidate 2 RHSP PF07999.11 EKX54863.1 - 0.14 10.9 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Retrotransposon hot spot protein Cyt_bd_oxida_II PF02322.15 EKX54864.1 - 0.022 14.1 19.3 0.03 13.7 19.3 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II Zn-ribbon_8 PF09723.10 EKX54864.1 - 0.032 14.3 0.1 0.087 13.0 0.1 1.6 1 0 0 1 1 1 0 Zinc ribbon domain GHMP_kinases_C PF08544.13 EKX54865.1 - 8.7e-11 42.0 0.1 2.6e-10 40.5 0.0 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 EKX54865.1 - 4.2e-10 39.0 0.1 7.8e-10 38.2 0.1 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature DUF2016 PF09436.10 EKX54865.1 - 0.15 11.8 0.0 6.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2016) Enkurin PF13864.6 EKX54867.1 - 1.9e-13 50.6 7.5 1.9e-13 50.6 7.5 2.1 2 1 0 2 2 2 1 Calmodulin-binding Seryl_tRNA_N PF02403.22 EKX54867.1 - 0.16 12.2 7.5 0.43 10.8 6.7 2.2 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1082 PF06449.11 EKX54867.1 - 0.26 11.1 2.6 15 5.5 0.5 2.3 2 0 0 2 2 2 0 Mitochondrial domain of unknown function (DUF1082) F-box-like PF12937.7 EKX54868.1 - 1.1e-08 34.8 0.8 2e-08 34.0 0.8 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EKX54868.1 - 1.3e-06 28.2 1.2 1.3e-06 28.2 1.2 1.9 2 0 0 2 2 2 1 F-box domain zf-H2C2_2 PF13465.6 EKX54871.1 - 4.2e-20 71.2 17.4 3.4e-10 39.9 1.2 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 EKX54871.1 - 2.1e-15 56.2 16.8 9.6e-06 25.8 1.7 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EKX54871.1 - 4.1e-13 49.0 16.2 0.00057 20.5 1.5 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EKX54871.1 - 4.6e-12 45.9 5.5 0.002 18.3 0.7 3.1 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EKX54871.1 - 2.3e-06 27.8 10.6 0.012 16.0 0.4 3.2 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EKX54871.1 - 2.8e-06 27.2 14.3 0.011 15.7 2.3 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2HE PF16278.5 EKX54871.1 - 3.6e-06 27.3 12.7 0.058 13.8 1.1 3.0 1 1 2 3 3 3 3 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 EKX54871.1 - 8e-05 22.7 2.1 8e-05 22.7 2.1 2.0 2 1 0 2 2 1 1 Zinc ribbon domain zf_UBZ PF18439.1 EKX54871.1 - 0.00012 21.5 6.9 0.013 15.1 1.2 2.8 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger C1_1 PF00130.22 EKX54871.1 - 0.00038 20.3 1.6 0.06 13.2 0.1 2.3 1 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-H2C2_5 PF13909.6 EKX54871.1 - 0.00054 19.7 0.7 0.00054 19.7 0.7 4.2 5 0 0 5 5 4 1 C2H2-type zinc-finger domain PhnA_Zn_Ribbon PF08274.12 EKX54871.1 - 0.0014 18.5 0.0 0.3 11.1 0.0 2.4 2 1 0 2 2 2 1 PhnA Zinc-Ribbon PHD PF00628.29 EKX54871.1 - 0.0015 18.4 1.8 0.0015 18.4 1.8 1.7 2 0 0 2 2 2 1 PHD-finger HypA PF01155.19 EKX54871.1 - 0.0015 18.5 1.0 0.0019 18.2 1.0 1.2 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS1595 PF12760.7 EKX54871.1 - 0.0091 16.0 7.5 0.12 12.4 0.5 2.7 1 1 2 3 3 3 2 Transposase zinc-ribbon domain CpXC PF14353.6 EKX54871.1 - 0.022 14.8 2.9 2 8.5 0.2 2.5 2 1 0 2 2 2 0 CpXC protein ATPase-cat_bd PF12156.8 EKX54871.1 - 0.025 15.3 3.6 0.18 12.5 0.4 2.1 1 1 0 2 2 2 0 Putative metal-binding domain of cation transport ATPase Zn_ribbon_SprT PF17283.2 EKX54871.1 - 0.028 14.3 1.6 0.78 9.7 0.0 2.9 2 1 1 3 3 3 0 SprT-like zinc ribbon domain Cys_rich_CPXG PF14255.6 EKX54871.1 - 0.031 14.2 3.1 1.7 8.6 0.0 2.7 3 0 0 3 3 3 0 Cysteine-rich CPXCG Elf1 PF05129.13 EKX54871.1 - 0.033 14.2 2.4 1.6 8.9 0.3 2.2 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like ADK_lid PF05191.14 EKX54871.1 - 0.052 13.5 5.4 1.8 8.6 0.2 2.8 2 1 1 3 3 3 0 Adenylate kinase, active site lid zinc_ribbon_15 PF17032.5 EKX54871.1 - 0.059 14.1 1.6 0.17 12.6 1.6 1.8 1 1 0 1 1 1 0 zinc-ribbon family zf-CHY PF05495.12 EKX54871.1 - 0.069 13.6 5.8 0.13 12.8 5.8 1.6 1 1 0 1 1 1 0 CHY zinc finger zf-BED PF02892.15 EKX54871.1 - 0.078 13.0 6.5 1.3 9.1 0.4 3.0 1 1 1 3 3 3 0 BED zinc finger FYDLN_acid PF09538.10 EKX54871.1 - 0.079 13.6 0.4 2.3 9.0 0.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zinc_ribbon_4 PF13717.6 EKX54871.1 - 0.097 12.6 6.6 2.5 8.1 0.3 3.1 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 EKX54871.1 - 0.11 12.6 5.8 0.33 11.0 5.8 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2_2 PF12756.7 EKX54871.1 - 0.13 12.6 6.7 62 4.0 6.7 2.9 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.11 EKX54871.1 - 0.13 12.2 4.3 10 6.1 0.6 3.1 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zinc_ribbon_9 PF14369.6 EKX54871.1 - 0.14 12.4 0.2 0.14 12.4 0.2 2.6 3 0 0 3 3 2 0 zinc-ribbon Nudix_N_2 PF14803.6 EKX54871.1 - 0.16 11.9 3.8 5.9 6.9 0.0 3.0 3 0 0 3 3 3 0 Nudix N-terminal zf-Mss51 PF13824.6 EKX54871.1 - 0.26 11.4 9.3 1.9 8.6 0.9 2.3 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 XPA_N PF01286.18 EKX54871.1 - 0.35 10.9 6.8 0.75 9.9 0.5 2.7 3 0 0 3 3 2 0 XPA protein N-terminal Evr1_Alr PF04777.13 EKX54871.1 - 0.44 11.0 3.0 3.4 8.2 0.2 2.3 1 1 1 2 2 2 0 Erv1 / Alr family Rubredoxin_2 PF18073.1 EKX54871.1 - 0.44 10.3 6.2 3.5 7.4 0.1 2.9 3 0 0 3 3 3 0 Rubredoxin metal binding domain zf-trcl PF13451.6 EKX54871.1 - 0.46 10.4 6.1 0.99 9.3 2.9 2.4 2 1 0 2 2 2 0 Probable zinc-ribbon domain PknG_rubred PF16919.5 EKX54871.1 - 0.53 10.4 5.1 6.3 7.0 0.3 2.5 1 1 2 3 3 3 0 Protein kinase G rubredoxin domain zf-RING_7 PF02591.15 EKX54871.1 - 0.6 10.3 6.6 4.9 7.4 0.1 2.6 3 0 0 3 3 2 0 C4-type zinc ribbon domain zf-AN1 PF01428.16 EKX54871.1 - 0.76 10.0 12.7 1.5 9.0 0.6 2.8 2 1 1 3 3 3 0 AN1-like Zinc finger YhfH PF14149.6 EKX54871.1 - 0.96 9.5 8.1 3.8 7.6 0.1 2.8 3 0 0 3 3 2 0 YhfH-like protein zf-HYPF PF07503.12 EKX54871.1 - 1.3 8.9 6.9 2.2 8.1 0.2 2.7 3 0 0 3 3 3 0 HypF finger zinc_ribbon_10 PF10058.9 EKX54871.1 - 1.3 8.8 5.0 20 5.0 2.5 2.5 1 1 1 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF983 PF06170.12 EKX54871.1 - 1.5 9.3 4.4 27 5.3 0.0 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF983) zf-C2H2_11 PF16622.5 EKX54871.1 - 1.6 8.6 10.7 3.6 7.4 0.2 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-Di19 PF05605.12 EKX54871.1 - 1.6 9.0 12.0 5.3 7.4 7.3 2.9 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf_C2H2_ZHX PF18387.1 EKX54871.1 - 1.9 8.2 10.0 1.3 8.7 2.6 2.5 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Prok-RING_1 PF14446.6 EKX54871.1 - 2.3 8.2 7.0 6.4 6.8 0.3 2.6 3 0 0 3 3 2 0 Prokaryotic RING finger family 1 OrfB_Zn_ribbon PF07282.11 EKX54871.1 - 2.3 8.2 5.5 21 5.1 3.3 2.3 1 1 1 2 2 2 0 Putative transposase DNA-binding domain DUF1610 PF07754.11 EKX54871.1 - 6.1 6.9 11.0 2.3 8.3 2.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) HlyIII PF03006.20 EKX54873.1 - 1.4e-31 109.9 20.0 2e-31 109.5 20.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related Rpn3_C PF08375.11 EKX54873.1 - 0.11 12.9 1.6 0.12 12.9 0.1 1.8 2 0 0 2 2 2 0 Proteasome regulatory subunit C-terminal Osmo_CC PF08946.10 EKX54874.1 - 0.056 13.7 0.4 0.11 12.8 0.4 1.4 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Herpes_UL25 PF01499.16 EKX54874.1 - 0.14 10.7 0.9 0.15 10.5 0.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF5549 PF17703.1 EKX54875.1 - 0.011 15.4 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5549) RRM_1 PF00076.22 EKX54876.1 - 2e-19 69.2 0.2 4.3e-19 68.1 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 EKX54876.1 - 6.4e-17 62.0 3.5 6.4e-17 62.0 3.5 2.2 2 1 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Pro_isomerase PF00160.21 EKX54877.1 - 5.1e-12 46.3 0.0 5.9e-12 46.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD BACK PF07707.15 EKX54880.1 - 1.1e-17 64.0 0.2 2.3e-17 63.0 0.2 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch BTB PF00651.31 EKX54880.1 - 4.5e-14 52.6 0.2 3.2e-13 49.9 0.1 2.2 1 1 1 2 2 2 1 BTB/POZ domain PDZ_6 PF17820.1 EKX54880.1 - 7.4e-07 28.9 0.0 1.6e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX54880.1 - 9.3e-06 25.9 0.1 4.8e-05 23.6 0.1 2.2 1 1 1 2 2 2 1 PDZ domain U-box PF04564.15 EKX54880.1 - 1.8e-05 24.8 0.0 8.3e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 U-box domain PDZ_2 PF13180.6 EKX54880.1 - 0.00039 20.7 0.1 0.00099 19.4 0.1 1.7 1 0 0 1 1 1 1 PDZ domain zf-NOSIP PF15906.5 EKX54880.1 - 0.028 14.5 0.0 0.085 13.0 0.0 1.8 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 EKX54880.1 - 0.04 13.7 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF2868 PF11067.8 EKX54880.1 - 0.24 10.9 8.1 0.43 10.0 2.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) ABC2_membrane PF01061.24 EKX54881.1 - 2e-57 194.0 54.9 6.1e-33 114.0 23.5 3.5 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 EKX54881.1 - 2.4e-36 125.3 0.0 5.5e-20 72.3 0.0 2.7 3 0 0 3 3 2 2 ABC transporter AAA_29 PF13555.6 EKX54881.1 - 3.4e-07 29.9 0.1 0.0047 16.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EKX54881.1 - 9.5e-07 28.9 0.0 0.0097 15.8 0.0 3.5 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EKX54881.1 - 2.9e-06 27.6 0.0 0.013 15.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EKX54881.1 - 5e-06 27.0 0.0 0.04 14.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain PDR_assoc PF08370.11 EKX54881.1 - 6.7e-06 25.8 7.7 0.0022 17.7 0.2 2.9 2 0 0 2 2 2 2 Plant PDR ABC transporter associated AAA PF00004.29 EKX54881.1 - 7.8e-06 26.4 0.6 0.18 12.2 0.0 3.3 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EKX54881.1 - 9.5e-05 22.4 0.2 0.0056 16.6 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EKX54881.1 - 0.0001 22.0 0.4 0.6 9.7 0.1 3.2 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.6 EKX54881.1 - 0.00014 22.0 0.0 0.46 10.7 0.0 3.6 3 0 0 3 3 3 1 Putative exonuclease SbcCD, C subunit ATPase_2 PF01637.18 EKX54881.1 - 0.00015 21.8 0.0 0.14 12.0 0.0 2.3 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea ABC2_membrane_3 PF12698.7 EKX54881.1 - 0.00057 19.1 18.2 0.00057 19.1 18.2 2.8 3 1 0 3 3 2 1 ABC-2 family transporter protein AAA_18 PF13238.6 EKX54881.1 - 0.00064 20.3 0.1 0.09 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EKX54881.1 - 0.00099 18.6 0.0 0.67 9.3 0.1 3.3 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 EKX54881.1 - 0.0022 17.7 1.1 2.7 7.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 EKX54881.1 - 0.004 17.1 0.3 3.4 7.5 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_30 PF13604.6 EKX54881.1 - 0.0043 16.8 0.4 1.8 8.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 EKX54881.1 - 0.0045 17.0 0.2 2.8 8.0 0.1 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EKX54881.1 - 0.0054 16.8 0.1 0.34 10.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EKX54881.1 - 0.0058 16.8 0.1 4 7.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 EKX54881.1 - 0.006 17.1 0.6 0.28 11.7 0.1 2.3 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 EKX54881.1 - 0.0069 16.1 0.6 4.4 7.0 0.3 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RuvB_N PF05496.12 EKX54881.1 - 0.0089 15.8 0.2 1.5 8.5 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EKX54881.1 - 0.0093 16.3 0.0 3.2 8.2 0.0 2.9 2 0 0 2 2 2 1 RNA helicase NTPase_1 PF03266.15 EKX54881.1 - 0.011 15.7 0.9 0.59 10.0 0.0 2.9 3 0 0 3 3 3 0 NTPase Roc PF08477.13 EKX54881.1 - 0.017 15.4 0.4 3.6 7.8 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 EKX54881.1 - 0.021 14.4 1.7 1.5 8.4 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 EKX54881.1 - 0.024 14.7 0.2 13 5.9 0.2 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 EKX54881.1 - 0.026 14.8 1.0 5.5 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EKX54881.1 - 0.03 14.7 0.7 1.2 9.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EKX54881.1 - 0.095 12.0 0.1 11 5.2 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.6 EKX54881.1 - 0.12 12.8 0.3 1.8 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EKX54881.1 - 0.18 11.5 0.0 78 2.8 0.1 3.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_5 PF07728.14 EKX54881.1 - 0.25 11.3 0.8 4.3 7.3 0.0 2.7 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Nuc_deoxyrib_tr PF05014.15 EKX54882.1 - 0.14 12.1 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase EphA2_TM PF14575.6 EKX54882.1 - 0.46 11.4 2.0 11 7.0 0.0 2.3 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain RWP-RK PF02042.15 EKX54883.1 - 5.5e-28 96.7 5.1 5.7e-18 64.6 0.2 2.6 2 0 0 2 2 2 2 RWP-RK domain MORN PF02493.20 EKX54885.1 - 5.2e-09 35.5 13.2 0.034 14.0 0.1 3.8 3 0 0 3 3 3 3 MORN repeat Spherulin4 PF12138.8 EKX54885.1 - 0.28 10.8 2.1 0.75 9.4 2.1 1.6 1 0 0 1 1 1 0 Spherulation-specific family 4 Colicin PF01024.19 EKX54885.1 - 1.2 9.0 5.5 0.46 10.3 2.4 1.8 2 0 0 2 2 2 0 Colicin pore forming domain BCDHK_Adom3 PF10436.9 EKX54886.1 - 1.3e-35 122.7 0.2 1.9e-35 122.1 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EKX54886.1 - 5.3e-09 36.6 0.0 1e-08 35.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EKX54886.1 - 0.022 14.6 0.0 0.049 13.5 0.0 1.5 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Beta_helix PF13229.6 EKX54888.1 - 1.9e-42 144.8 42.6 5.2e-19 68.6 6.0 3.2 1 1 2 3 3 3 3 Right handed beta helix region NosD PF05048.13 EKX54888.1 - 1.2e-27 96.8 21.5 4.1e-11 42.6 0.6 3.4 1 1 2 3 3 3 3 Periplasmic copper-binding protein (NosD) TfuA PF07812.12 EKX54888.1 - 5.8e-06 26.0 6.0 0.47 10.2 0.1 4.6 4 1 1 5 5 5 3 TfuA-like protein PA14 PF07691.12 EKX54889.1 - 3.1e-21 75.7 0.0 3.6e-06 26.8 0.0 3.3 3 0 0 3 3 3 3 PA14 domain Collagen PF01391.18 EKX54889.1 - 0.035 13.9 4.0 0.078 12.8 4.0 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) SlyX PF04102.12 EKX54890.1 - 0.0002 21.9 26.0 0.023 15.3 1.3 5.1 4 0 0 4 4 4 3 SlyX DUF1811 PF08838.10 EKX54890.1 - 2.1 8.6 5.9 4.3 7.6 0.6 3.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1811) DUF3727 PF12527.8 EKX54891.1 - 4.8e-09 36.3 0.8 3.6e-08 33.5 1.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3727) Pkinase PF00069.25 EKX54892.1 - 2.1e-67 227.3 0.0 2.4e-67 227.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX54892.1 - 5e-24 85.0 0.0 7.7e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX54892.1 - 0.016 14.5 0.1 0.19 11.0 0.0 2.4 2 1 2 4 4 4 0 Kinase-like Haspin_kinase PF12330.8 EKX54892.1 - 0.023 13.7 0.1 0.21 10.5 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 EKX54892.1 - 0.085 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EKX54892.1 - 0.16 11.6 0.3 0.51 9.9 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 IGPD PF00475.18 EKX54893.1 - 2e-60 203.3 1.5 2.9e-60 202.8 1.5 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Atx10homo_assoc PF09759.9 EKX54895.1 - 1.2e-35 121.5 0.7 2.8e-34 117.1 0.2 2.3 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain DUF438 PF04282.13 EKX54895.1 - 0.059 13.3 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF438) YscJ_FliF PF01514.17 EKX54895.1 - 0.063 12.9 0.1 0.95 9.1 0.0 2.0 2 0 0 2 2 2 0 Secretory protein of YscJ/FliF family Arm_2 PF04826.13 EKX54895.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Armadillo-like WD40 PF00400.32 EKX54897.1 - 8.2e-34 115.1 13.8 2.2e-06 28.3 0.6 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX54897.1 - 6.1e-06 26.4 0.0 0.088 13.1 0.0 3.2 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Invas_SpaK PF03519.14 EKX54897.1 - 0.032 14.3 0.0 0.31 11.1 0.0 2.3 2 1 0 2 2 2 0 Invasion protein B family Peptidase_M6 PF05547.11 EKX54897.1 - 0.2 9.9 0.0 0.26 9.6 0.0 1.1 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 WD40_like PF17005.5 EKX54897.1 - 0.21 10.9 0.0 0.48 9.7 0.0 1.6 2 1 0 2 2 2 0 WD40-like domain PH PF00169.29 EKX54899.1 - 3.2e-13 50.1 1.2 9.2e-12 45.4 0.0 3.0 3 0 0 3 3 3 1 PH domain PDZ PF00595.24 EKX54899.1 - 0.0021 18.4 0.0 0.0054 17.1 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PH_9 PF15410.6 EKX54899.1 - 0.038 14.3 0.1 0.11 12.9 0.1 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 EKX54899.1 - 0.16 12.4 2.9 0.56 10.7 0.1 3.3 3 0 0 3 3 3 0 Pleckstrin homology domain Fib_alpha PF08702.10 EKX54899.1 - 0.8 9.9 8.6 0.36 11.0 0.2 3.3 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 EKX54899.1 - 8.7 6.4 14.7 6.9 6.7 1.3 3.6 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus SLATT_1 PF18181.1 EKX54900.1 - 2.9e-18 65.9 2.7 4e-18 65.5 2.7 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain 1 DUF677 PF05055.12 EKX54900.1 - 0.34 9.7 2.0 0.45 9.4 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) SET PF00856.28 EKX54901.1 - 1.6e-08 35.1 0.0 1.8e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 SET domain PAP_assoc PF03828.19 EKX54902.1 - 2.5e-07 30.8 0.2 5.6e-07 29.7 0.2 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EKX54902.1 - 0.096 13.0 0.0 0.17 12.2 0.0 1.5 1 1 0 1 1 1 0 Nucleotidyltransferase domain GIIM PF08388.11 EKX54903.1 - 0.0022 18.0 0.0 0.004 17.2 0.0 1.4 1 0 0 1 1 1 1 Group II intron, maturase-specific domain SOGA PF11365.8 EKX54903.1 - 0.028 15.6 0.7 0.042 15.0 0.7 1.3 1 0 0 1 1 1 0 Protein SOGA CVNH PF08881.10 EKX54904.1 - 2.7e-07 31.2 3.2 5.7e-07 30.1 2.9 1.6 1 1 0 1 1 1 1 CVNH domain Peptidase_S8 PF00082.22 EKX54905.1 - 6e-37 127.5 0.0 6.8e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 Subtilase family SUI1 PF01253.22 EKX54906.1 - 2.4e-13 50.4 0.0 5.9e-13 49.1 0.0 1.7 2 0 0 2 2 2 1 Translation initiation factor SUI1 IQ PF00612.27 EKX54907.1 - 2.2e-07 30.1 4.6 0.011 15.5 0.1 3.7 3 0 0 3 3 3 3 IQ calmodulin-binding motif DnaG_DnaB_bind PF08278.11 EKX54907.1 - 0.19 12.4 1.4 0.34 11.5 1.0 1.6 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding Cript PF10235.9 EKX54908.1 - 8.8e-21 74.3 1.3 1.2e-20 73.9 1.3 1.2 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT DZR PF12773.7 EKX54908.1 - 0.064 13.3 4.0 0.22 11.6 4.1 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_5 PF14634.6 EKX54908.1 - 0.14 12.2 5.6 0.28 11.2 5.6 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EKX54908.1 - 0.15 12.0 4.2 0.29 11.0 4.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf_UBZ PF18439.1 EKX54908.1 - 0.32 10.6 0.1 0.32 10.6 0.1 2.4 2 1 1 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C3HC4_3 PF13920.6 EKX54908.1 - 1 9.3 7.7 4.3 7.3 7.7 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IMS PF00817.20 EKX54909.1 - 0.16 12.0 2.4 0.55 10.2 0.9 2.7 2 0 0 2 2 2 0 impB/mucB/samB family MCD_N PF17408.2 EKX54909.1 - 8.7 6.6 9.0 1.8 8.7 0.7 4.2 4 0 0 4 4 4 0 Malonyl-CoA decarboxylase N-terminal domain Cyt-b5 PF00173.28 EKX54910.1 - 3.2e-13 49.6 0.0 3.5e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Peptidase_S8 PF00082.22 EKX54911.1 - 4.9e-44 150.8 0.2 6e-44 150.5 0.2 1.1 1 0 0 1 1 1 1 Subtilase family ATP-sulfurylase PF01747.17 EKX54914.1 - 4e-71 238.9 0.0 6.3e-71 238.2 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 EKX54914.1 - 1.1e-39 135.6 0.0 1.8e-39 135.0 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain Aldo_ket_red PF00248.21 EKX54915.1 - 6.1e-24 84.7 0.0 8.2e-23 81.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family ARL2_Bind_BART PF11527.8 EKX54916.1 - 2.3e-21 76.0 0.5 4.1e-21 75.2 0.5 1.3 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART Phage_AlpA PF05930.12 EKX54916.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Prophage CP4-57 regulatory protein (AlpA) Hemocyanin_N PF03722.14 EKX54916.1 - 0.051 14.1 0.0 0.12 12.9 0.0 1.6 1 1 0 1 1 1 0 Hemocyanin, all-alpha domain Abhydrolase_1 PF00561.20 EKX54917.1 - 0.00021 21.0 0.6 0.0013 18.4 0.2 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EKX54917.1 - 0.0038 17.9 1.1 0.0038 17.9 1.1 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EKX54917.1 - 0.0076 15.5 0.3 0.093 12.0 0.2 2.4 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EKX54917.1 - 0.036 13.5 0.1 0.068 12.6 0.1 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_8 PF06259.12 EKX54917.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Ion_trans PF00520.31 EKX54919.1 - 1.2e-33 116.3 21.8 1.8e-33 115.8 21.8 1.2 1 0 0 1 1 1 1 Ion transport protein EF-hand_1 PF00036.32 EKX54919.1 - 3.6e-05 23.0 0.1 0.00015 21.1 0.1 2.2 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EKX54919.1 - 0.00065 19.4 0.2 0.0033 17.3 0.2 2.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 EKX54919.1 - 0.0013 19.1 5.9 0.014 15.8 0.7 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EKX54919.1 - 0.0056 16.5 0.4 0.021 14.7 0.2 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EKX54919.1 - 0.017 14.6 0.1 0.046 13.2 0.1 1.8 1 0 0 1 1 1 0 EF hand Duffy_binding PF05424.11 EKX54919.1 - 0.037 14.1 0.1 0.072 13.1 0.1 1.5 1 0 0 1 1 1 0 Duffy binding domain DUF3169 PF11368.8 EKX54919.1 - 0.13 11.8 0.1 0.13 11.8 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) DUF4834 PF16118.5 EKX54919.1 - 0.67 11.0 0.1 0.67 11.0 0.1 3.5 5 1 0 5 5 5 0 Domain of unknown function (DUF4834) UPF0449 PF15136.6 EKX54919.1 - 4.6 7.8 5.1 0.69 10.4 0.7 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 NUDIX PF00293.28 EKX54920.1 - 8.2e-20 71.2 0.0 1.1e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Nudix_hydro PF18290.1 EKX54920.1 - 6.8e-15 54.8 0.3 1e-14 54.3 0.3 1.3 1 0 0 1 1 1 1 Nudix hydrolase domain PDZ_2 PF13180.6 EKX54921.1 - 0.025 14.9 0.0 0.039 14.3 0.0 1.4 1 1 0 1 1 1 0 PDZ domain PDZ_6 PF17820.1 EKX54921.1 - 0.07 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 PDZ domain DUF2437 PF10370.9 EKX54921.1 - 0.12 13.3 0.0 0.35 11.8 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF2437) AMPK1_CBM PF16561.5 EKX54922.1 - 7.6e-13 48.5 0.0 1.8e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase RWP-RK PF02042.15 EKX54925.1 - 8.9e-17 60.8 0.1 2e-16 59.7 0.1 1.5 1 0 0 1 1 1 1 RWP-RK domain Sigma70_r4_2 PF08281.12 EKX54925.1 - 0.074 12.7 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 TPT PF03151.16 EKX54926.1 - 9e-39 133.6 17.3 1.2e-38 133.2 17.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EKX54926.1 - 2.7e-07 30.8 24.2 0.00011 22.4 8.6 2.8 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 EKX54926.1 - 0.00038 19.8 17.7 0.00062 19.1 17.7 1.3 1 0 0 1 1 1 1 UAA transporter family DUF4483 PF14825.6 EKX54927.1 - 3.2e-06 27.0 2.7 0.27 11.0 0.2 4.1 2 2 2 5 5 5 4 Domain of unknown function (DUF4483) Pkinase PF00069.25 EKX54928.1 - 3.5e-41 141.3 0.0 4.2e-41 141.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX54928.1 - 3.3e-21 75.7 0.0 3.6e-21 75.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX54928.1 - 7.6e-06 26.0 0.0 0.029 14.3 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EKX54928.1 - 0.00061 19.4 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 EKX54928.1 - 0.00099 18.0 0.0 0.0017 17.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 EKX54928.1 - 0.0022 17.6 0.0 0.0079 15.8 0.0 1.7 1 1 1 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.22 EKX54928.1 - 0.0031 17.1 0.0 0.005 16.4 0.0 1.4 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 EKX54928.1 - 0.065 12.6 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 EKX54928.1 - 0.2 10.6 0.1 0.31 10.0 0.0 1.4 1 1 0 1 1 1 0 Poxvirus serine/threonine protein kinase Peptidase_S41 PF03572.18 EKX54929.1 - 9.6e-41 139.1 2.8 1.8e-20 73.2 0.5 3.2 3 0 0 3 3 3 2 Peptidase family S41 PDZ_6 PF17820.1 EKX54929.1 - 4e-10 39.4 0.0 1e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX54929.1 - 9e-08 32.3 0.1 2.7e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 EKX54929.1 - 9.2e-07 29.1 0.0 2.3e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX54929.1 - 0.027 14.4 0.0 0.085 12.8 0.0 1.8 1 0 0 1 1 1 0 Tricorn protease PDZ domain ESPR PF13018.6 EKX54929.1 - 0.087 12.6 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 Extended Signal Peptide of Type V secretion system Peptidase_M17 PF00883.21 EKX54931.1 - 1e-99 333.8 1.5 1.4e-99 333.3 1.5 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 EKX54931.1 - 2.9e-13 50.2 0.2 7.1e-13 48.9 0.2 1.7 1 0 0 1 1 1 1 M17 aminopeptidase N-terminal domain 2 FAST_1 PF06743.15 EKX54932.1 - 0.028 14.4 7.4 0.64 10.0 0.0 5.1 4 1 1 5 5 5 0 FAST kinase-like protein, subdomain 1 STT3 PF02516.14 EKX54933.1 - 2.9e-31 108.9 16.8 2.1e-28 99.5 16.8 3.0 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit FR47 PF08445.10 EKX54934.1 - 0.00025 21.0 0.0 0.00072 19.5 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 EKX54934.1 - 0.011 16.4 0.0 0.017 15.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Gly_acyl_tr_C PF08444.10 EKX54934.1 - 0.024 14.9 0.0 0.05 13.8 0.0 1.6 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Acetyltransf_1 PF00583.25 EKX54934.1 - 0.12 12.6 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF4558 PF15104.6 EKX54935.1 - 9.5e-11 41.6 10.3 1.4e-10 41.1 9.8 1.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4558) INCA1 PF15142.6 EKX54935.1 - 0.014 15.5 0.2 0.014 15.4 0.2 1.1 1 0 0 1 1 1 0 INCA1 KIF1B PF12423.8 EKX54935.1 - 0.51 10.8 4.6 0.61 10.6 0.3 2.3 2 1 0 2 2 2 0 Kinesin protein 1B Pyr_redox_2 PF07992.14 EKX54937.1 - 1.2e-27 96.9 0.2 1.7e-27 96.4 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AIRS_C PF02769.22 EKX54937.1 - 1.1e-17 64.6 0.0 2e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 EKX54937.1 - 4.6e-13 49.6 0.4 1.2e-12 48.3 0.4 1.8 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Pyr_redox PF00070.27 EKX54937.1 - 2.5e-08 34.4 0.1 7.7e-08 32.8 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EKX54937.1 - 0.0021 17.4 0.4 0.0059 15.9 0.4 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase PTS_2-RNA PF01885.16 EKX54937.1 - 0.2 11.7 0.0 0.37 10.8 0.0 1.3 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF3449 PF11931.8 EKX54938.1 - 9.4 6.0 13.0 3.4 7.4 9.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) Got1 PF04178.12 EKX54939.1 - 5.6e-12 46.1 11.0 6.6e-12 45.9 11.0 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF308 PF03729.13 EKX54939.1 - 5.5 7.4 14.8 0.35 11.2 9.7 1.6 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) Tup_N PF08581.10 EKX54940.1 - 2e-21 76.1 9.3 2.7e-21 75.6 9.3 1.2 1 0 0 1 1 1 1 Tup N-terminal WD40 PF00400.32 EKX54940.1 - 4.9e-05 24.0 0.0 9.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 WD domain, G-beta repeat zf-C4H2 PF10146.9 EKX54940.1 - 9.3e-05 22.8 0.8 0.0001 22.7 0.8 1.2 1 0 0 1 1 1 1 Zinc finger-containing protein Spc7 PF08317.11 EKX54940.1 - 0.0011 17.9 5.6 0.0015 17.5 5.6 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF3450 PF11932.8 EKX54940.1 - 0.0026 17.1 8.1 0.0038 16.6 8.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Borrelia_lipo_1 PF05714.11 EKX54940.1 - 0.0033 17.2 2.0 0.0044 16.8 2.0 1.1 1 0 0 1 1 1 1 Borrelia burgdorferi virulent strain associated lipoprotein Syntaxin PF00804.25 EKX54940.1 - 0.0033 17.1 3.4 0.0049 16.6 3.4 1.2 1 0 0 1 1 1 1 Syntaxin CK2S PF15011.6 EKX54940.1 - 0.0055 16.6 2.1 0.0095 15.8 2.1 1.4 1 0 0 1 1 1 1 Casein Kinase 2 substrate FliJ PF02050.16 EKX54940.1 - 0.0082 16.4 8.8 0.013 15.7 8.8 1.2 1 0 0 1 1 1 1 Flagellar FliJ protein MscS_porin PF12795.7 EKX54940.1 - 0.014 14.9 8.8 0.021 14.3 8.8 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF1664 PF07889.12 EKX54940.1 - 0.015 15.3 2.2 0.028 14.5 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) SANT_DAMP1_like PF16282.5 EKX54940.1 - 0.02 15.1 0.5 0.032 14.4 0.5 1.3 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 CortBP2 PF09727.9 EKX54940.1 - 0.02 14.8 3.7 0.031 14.2 3.7 1.2 1 0 0 1 1 1 0 Cortactin-binding protein-2 Bacillus_HBL PF05791.11 EKX54940.1 - 0.021 14.7 5.3 0.033 14.0 5.3 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) PV-1 PF06637.11 EKX54940.1 - 0.022 13.6 0.7 0.024 13.5 0.7 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) APG17 PF04108.12 EKX54940.1 - 0.027 13.6 4.4 0.042 13.0 4.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 EzrA PF06160.12 EKX54940.1 - 0.03 12.5 5.3 0.04 12.1 5.3 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Fib_alpha PF08702.10 EKX54940.1 - 0.053 13.7 4.3 0.077 13.2 4.3 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family CCDC14 PF15254.6 EKX54940.1 - 0.065 11.9 8.1 0.087 11.5 8.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 ADIP PF11559.8 EKX54940.1 - 0.067 13.3 9.1 0.11 12.5 9.1 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Cortex-I_coil PF09304.10 EKX54940.1 - 0.08 13.2 3.3 0.13 12.5 3.3 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil OmpH PF03938.14 EKX54940.1 - 0.12 12.7 7.9 0.17 12.2 7.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TMPIT PF07851.13 EKX54940.1 - 0.13 11.5 4.3 0.17 11.1 4.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF1640 PF07798.11 EKX54940.1 - 0.14 12.2 5.5 0.26 11.3 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) FapA PF03961.13 EKX54940.1 - 0.17 10.5 2.4 0.22 10.1 2.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A KIP1 PF07765.12 EKX54940.1 - 0.21 11.7 2.9 0.35 11.0 2.9 1.3 1 0 0 1 1 1 0 KIP1-like protein Prominin PF05478.11 EKX54940.1 - 0.34 8.8 2.2 0.43 8.5 2.2 1.1 1 0 0 1 1 1 0 Prominin SseC PF04888.12 EKX54940.1 - 1.9 8.0 4.9 2.8 7.5 4.9 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family ZapB PF06005.12 EKX54940.1 - 3.4 8.2 11.3 6.2 7.3 10.6 1.9 1 1 1 2 2 2 0 Cell division protein ZapB COMP PF11598.8 EKX54940.1 - 6.7 7.3 8.8 6.9 7.2 0.2 2.8 1 1 2 3 3 3 0 Cartilage oligomeric matrix protein WD40 PF00400.32 EKX54941.1 - 2.6e-56 186.3 19.3 2.2e-09 37.8 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX54941.1 - 2.4e-15 56.6 0.0 0.0015 18.8 0.0 5.8 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EKX54941.1 - 1.2e-07 31.4 0.1 0.013 14.9 0.0 3.8 4 0 0 4 4 4 2 WD40-like domain Nup160 PF11715.8 EKX54941.1 - 1.4e-06 27.3 0.0 0.26 9.9 0.0 4.1 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EKX54941.1 - 2.2e-06 26.9 0.4 0.013 14.4 0.1 4.1 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EKX54941.1 - 0.00075 18.1 1.5 0.045 12.3 0.2 2.8 1 1 0 2 2 2 1 Cytochrome D1 heme domain Nbas_N PF15492.6 EKX54941.1 - 0.0011 18.4 0.1 0.47 9.7 0.0 2.9 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal VID27 PF08553.10 EKX54941.1 - 0.0027 16.8 0.0 11 5.0 0.0 3.2 2 1 1 3 3 3 2 VID27 C-terminal WD40-like domain Nucleoporin_N PF08801.11 EKX54941.1 - 0.0031 16.3 0.0 0.59 8.8 0.0 3.2 3 1 1 4 4 4 1 Nup133 N terminal like Tup_N PF08581.10 EKX54942.1 - 4e-26 91.1 6.8 5.4e-26 90.7 6.8 1.2 1 0 0 1 1 1 1 Tup N-terminal Spc7 PF08317.11 EKX54942.1 - 9.2e-05 21.5 3.3 0.00012 21.1 3.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Prp19 PF08606.11 EKX54942.1 - 0.00065 19.6 0.5 0.0014 18.6 0.5 1.6 1 1 0 1 1 1 1 Prp19/Pso4-like SHE3 PF17078.5 EKX54942.1 - 0.0038 17.0 3.6 0.0059 16.4 3.6 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 ADIP PF11559.8 EKX54942.1 - 0.0043 17.2 3.5 0.0063 16.6 3.5 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 EKX54942.1 - 0.0046 16.3 5.1 0.0065 15.8 5.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) CENP-Q PF13094.6 EKX54942.1 - 0.0047 17.1 0.1 0.0057 16.9 0.1 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit WXG100 PF06013.12 EKX54942.1 - 0.009 16.2 1.9 0.018 15.3 1.9 1.5 1 0 0 1 1 1 1 Proteins of 100 residues with WXG Jnk-SapK_ap_N PF09744.9 EKX54942.1 - 0.012 15.9 4.6 0.017 15.3 4.6 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 SKA2 PF16740.5 EKX54942.1 - 0.014 15.2 2.1 0.023 14.5 2.1 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 TSNAXIP1_N PF15739.5 EKX54942.1 - 0.014 15.7 2.0 0.028 14.8 2.0 1.4 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus DUF724 PF05266.14 EKX54942.1 - 0.025 14.4 2.2 0.034 14.0 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Prefoldin_2 PF01920.20 EKX54942.1 - 0.052 13.5 8.4 0.87 9.6 2.4 2.2 1 1 1 2 2 2 0 Prefoldin subunit APG6_N PF17675.1 EKX54942.1 - 0.063 13.8 7.2 0.093 13.3 7.2 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DivIVA PF05103.13 EKX54942.1 - 0.077 13.1 2.5 0.13 12.4 2.5 1.3 1 0 0 1 1 1 0 DivIVA protein TMPIT PF07851.13 EKX54942.1 - 0.12 11.7 0.7 0.15 11.3 0.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein HALZ PF02183.18 EKX54942.1 - 0.46 10.7 7.7 0.11 12.7 2.5 2.6 3 1 0 3 3 3 0 Homeobox associated leucine zipper Bap31_Bap29_C PF18035.1 EKX54942.1 - 0.79 9.8 5.2 2.5 8.2 0.8 2.4 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Swi5 PF07061.11 EKX54942.1 - 1.2 9.3 5.3 7.5 6.7 1.6 2.8 2 1 1 3 3 3 0 Swi5 Arm PF00514.23 EKX54943.1 - 8.2e-41 136.8 24.8 7.3e-07 29.0 1.4 7.6 7 1 0 7 7 7 6 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EKX54943.1 - 0.00079 19.8 5.9 0.03 14.7 1.4 3.5 1 1 3 4 4 4 2 HEAT repeats Atx10homo_assoc PF09759.9 EKX54943.1 - 0.0012 18.9 3.2 0.2 11.7 0.0 3.7 2 2 2 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 EKX54943.1 - 0.0052 16.3 0.8 0.39 10.1 0.1 3.0 1 1 1 3 3 3 1 Armadillo-like RICTOR_N PF14664.6 EKX54943.1 - 0.017 14.1 0.0 0.032 13.2 0.0 1.5 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term HEAT_EZ PF13513.6 EKX54943.1 - 0.021 15.3 13.3 38 4.9 0.8 5.8 4 1 2 6 6 6 0 HEAT-like repeat HEAT PF02985.22 EKX54943.1 - 2.8 8.5 19.4 20 5.8 1.6 6.5 6 1 0 6 6 6 0 HEAT repeat DHHC PF01529.20 EKX54944.1 - 1.2e-34 119.3 10.4 1.3e-34 119.2 10.4 1.0 1 0 0 1 1 1 1 DHHC palmitoyltransferase Papilloma_E5 PF03025.14 EKX54944.1 - 0.097 12.8 9.2 0.85 9.8 1.7 2.2 2 0 0 2 2 2 0 Papillomavirus E5 Pro_isomerase PF00160.21 EKX54946.1 - 3.1e-50 170.5 0.1 4.6e-50 170.0 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PDZ_6 PF17820.1 EKX54946.1 - 0.00022 21.0 0.0 0.00048 19.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX54946.1 - 0.017 15.5 0.0 0.042 14.2 0.0 1.7 1 0 0 1 1 1 0 PDZ domain Thioredoxin_3 PF13192.6 EKX54946.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin domain Nup54 PF13874.6 EKX54949.1 - 3.4e-16 59.6 3.2 3.4e-16 59.6 3.2 1.6 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 APG17 PF04108.12 EKX54949.1 - 0.04 13.0 3.6 0.059 12.5 3.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 Nup54_C PF18437.1 EKX54949.1 - 0.091 12.7 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Nup54 C-terminal interacting domain Peptidase_M13 PF01431.21 EKX54950.1 - 1.1e-59 201.5 0.2 2.4e-59 200.4 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13_N PF05649.13 EKX54950.1 - 7.5e-59 200.3 0.9 7e-57 193.8 0.0 2.7 2 1 1 3 3 3 2 Peptidase family M13 YHYH PF14240.6 EKX54951.1 - 6.1e-05 23.0 1.6 0.12 12.3 0.8 2.0 1 1 1 2 2 2 2 YHYH protein FA_desaturase PF00487.24 EKX54952.1 - 1e-28 100.9 10.9 1.4e-28 100.4 10.9 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 EKX54952.1 - 6.1e-15 54.4 0.4 1.1e-14 53.6 0.4 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Popeye PF04831.13 EKX54953.1 - 1.6e-06 28.4 0.9 2e-06 28.0 0.9 1.5 1 1 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.29 EKX54953.1 - 2.4e-05 24.3 0.1 4.8e-05 23.3 0.1 1.6 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain YnfE PF17452.2 EKX54953.1 - 0.2 12.0 0.8 0.69 10.2 0.4 1.9 2 0 0 2 2 2 0 Uncharacterized YnfE-like Pkinase PF00069.25 EKX54954.1 - 1.6e-36 126.0 0.0 1.9e-36 125.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX54954.1 - 7.6e-22 77.8 0.0 8.6e-22 77.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX54954.1 - 1.6e-05 24.4 0.0 2.1e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 EKX54954.1 - 0.3 10.0 0.0 0.41 9.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase NumbF PF06311.12 EKX54955.1 - 0.029 14.9 0.5 0.06 13.9 0.1 1.8 1 1 0 2 2 2 0 NUMB domain PCMT PF01135.19 EKX54957.1 - 5.3e-77 258.3 0.0 6.9e-77 257.9 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EKX54957.1 - 4.4e-07 29.8 0.0 2.7e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EKX54957.1 - 7.1e-05 22.3 0.0 8.5e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EKX54957.1 - 0.00033 21.3 0.0 0.0011 19.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 EKX54957.1 - 0.00073 19.6 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX54957.1 - 0.0012 18.7 0.0 0.0046 16.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX54957.1 - 0.0032 16.8 0.0 0.0052 16.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EKX54957.1 - 0.012 16.2 0.1 0.057 14.1 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 EKX54957.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 EKX54957.1 - 0.034 13.7 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MTS PF05175.14 EKX54957.1 - 0.036 13.6 0.1 0.073 12.6 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Fibrillarin PF01269.17 EKX54957.1 - 0.12 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin DnaJ PF00226.31 EKX54958.1 - 3.5e-15 55.9 0.4 5.6e-15 55.2 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain Trm112p PF03966.16 EKX54959.1 - 1.7e-12 47.7 0.0 2.3e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein DUF469 PF04320.14 EKX54959.1 - 0.054 14.4 0.2 0.07 14.0 0.2 1.1 1 0 0 1 1 1 0 Protein with unknown function (DUF469) RbpA PF13397.6 EKX54960.1 - 0.11 13.2 0.1 0.3 11.7 0.1 1.7 1 0 0 1 1 1 0 RNA polymerase-binding protein tRNA-synt_1e PF01406.19 EKX54961.1 - 5.9e-117 390.3 0.0 1.2e-115 386.0 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DALR_2 PF09190.11 EKX54961.1 - 0.0014 19.1 0.1 0.0058 17.1 0.1 2.1 1 0 0 1 1 1 1 DALR domain tRNA-synt_1c PF00749.21 EKX54961.1 - 0.03 13.2 1.2 0.056 12.3 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain DUF4710 PF15828.5 EKX54961.1 - 0.076 13.1 4.8 3.9 7.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) DUF5623 PF18536.1 EKX54961.1 - 0.12 12.7 0.3 0.52 10.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5623) T3SS_needle_F PF09392.10 EKX54961.1 - 0.13 12.5 1.0 2.2 8.6 0.1 2.8 2 0 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF tRNA-synt_1g PF09334.11 EKX54961.1 - 0.15 10.8 0.3 5.7 5.6 0.1 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (M) DUF1488 PF07369.11 EKX54961.1 - 0.51 10.4 3.5 0.6 10.1 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1488) DUF3584 PF12128.8 EKX54961.1 - 0.92 6.9 8.4 0.089 10.3 3.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) PP2C PF00481.21 EKX54962.1 - 2.7e-66 223.8 0.5 3.1e-66 223.6 0.5 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EKX54962.1 - 0.00016 21.7 1.5 0.015 15.2 0.0 2.1 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) N2227 PF07942.12 EKX54964.1 - 2.1e-88 296.0 0.0 2.9e-88 295.6 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 EKX54964.1 - 0.022 15.5 0.0 0.35 11.6 0.0 2.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EKX54964.1 - 0.061 13.2 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 EKX54965.1 - 1.3e-36 126.3 0.0 1.5e-36 126.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX54965.1 - 8.9e-15 54.7 0.0 1.1e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX54965.1 - 0.0011 19.0 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family PDZ_6 PF17820.1 EKX54966.1 - 3.3e-49 164.5 8.8 3.3e-10 39.7 0.1 7.9 7 0 0 7 7 7 7 PDZ domain PDZ PF00595.24 EKX54966.1 - 1.2e-41 141.0 2.3 6e-08 32.9 0.0 7.5 7 0 0 7 7 7 6 PDZ domain PDZ_2 PF13180.6 EKX54966.1 - 9.4e-32 109.2 12.2 6e-06 26.5 0.0 7.9 8 0 0 8 8 8 6 PDZ domain Tricorn_PDZ PF14685.6 EKX54966.1 - 3.5e-16 58.9 7.5 0.22 11.5 0.0 8.0 7 1 0 7 7 7 6 Tricorn protease PDZ domain PDZ_4 PF17816.1 EKX54966.1 - 1.8e-06 28.3 0.4 26 5.3 0.0 7.0 7 0 0 7 7 7 0 PDZ domain V_ATPase_I PF01496.19 EKX54966.1 - 0.061 11.2 25.2 0.011 13.7 13.8 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Chitin_synth_1 PF01644.17 EKX54966.1 - 0.2 11.6 2.3 0.38 10.7 2.3 1.4 1 0 0 1 1 1 0 Chitin synthase GTP_EFTU PF00009.27 EKX54967.1 - 4.3e-45 153.6 0.0 6.1e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EKX54967.1 - 6.5e-12 45.7 0.1 2.6e-10 40.5 0.1 2.7 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 EKX54967.1 - 3.3e-10 40.2 0.0 4.1e-09 36.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 EKX54967.1 - 2.5e-06 27.5 0.0 0.00045 20.3 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EKX54967.1 - 0.0027 17.6 0.2 0.0081 16.0 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 KTI12 PF08433.10 EKX54967.1 - 0.21 11.0 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Peptidase_S9_N PF02897.15 EKX54968.1 - 8.3e-55 186.3 0.0 1.2e-54 185.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 EKX54968.1 - 2.6e-39 134.9 0.0 4.1e-39 134.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EKX54968.1 - 0.002 17.7 0.2 0.0036 17.0 0.2 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 EKX54968.1 - 0.05 13.2 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold UTP15_C PF09384.10 EKX54969.1 - 3e-39 134.0 0.2 4.8e-39 133.4 0.2 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 EKX54969.1 - 1e-24 86.3 8.5 8.9e-07 29.5 0.2 7.3 7 1 1 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX54969.1 - 2.5e-10 40.5 0.0 0.0061 16.8 0.0 4.4 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EKX54969.1 - 2.5e-05 24.0 0.3 0.12 11.9 0.4 2.3 1 1 1 2 2 2 2 PQQ-like domain ROS_MUCR PF05443.11 EKX54969.1 - 0.088 12.9 0.0 0.26 11.4 0.0 1.8 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein Sterol_MT_C PF08498.10 EKX54971.1 - 6.4e-23 80.9 0.1 1e-22 80.2 0.1 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EKX54971.1 - 2.8e-20 72.8 0.0 5e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX54971.1 - 1.8e-17 63.8 0.0 3.3e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX54971.1 - 2.8e-16 59.7 0.0 4e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EKX54971.1 - 7.8e-16 58.2 0.0 1e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EKX54971.1 - 7.1e-14 52.0 0.0 1e-13 51.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX54971.1 - 2.7e-11 43.2 0.0 4e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EKX54971.1 - 2.6e-10 40.9 0.0 4.6e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EKX54971.1 - 0.00027 20.6 0.0 0.0004 20.0 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.16 EKX54971.1 - 0.033 12.8 0.0 0.041 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase TehB PF03848.14 EKX54971.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB PCMT PF01135.19 EKX54971.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Dus PF01207.17 EKX54972.1 - 1.1e-61 208.6 0.0 1.5e-61 208.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EKX54972.1 - 0.0013 18.2 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein PRAS PF15798.5 EKX54972.1 - 0.15 12.7 0.0 0.25 11.9 0.0 1.5 1 1 0 1 1 1 0 Proline-rich AKT1 substrate 1 TIG PF01833.24 EKX54973.1 - 1.1e-72 240.1 208.1 1.7e-13 50.4 4.7 32.2 33 1 1 34 34 34 24 IPT/TIG domain TIG PF01833.24 EKX54974.1 - 2e-27 95.1 43.9 2e-10 40.6 1.9 8.4 8 0 0 8 8 8 7 IPT/TIG domain TIG PF01833.24 EKX54975.1 - 1.9e-18 66.3 7.5 2.2e-11 43.7 1.9 2.2 2 0 0 2 2 2 2 IPT/TIG domain Filamin PF00630.19 EKX54976.1 - 1.8e-26 92.9 0.0 3.5e-11 43.9 0.0 3.0 3 0 0 3 3 3 3 Filamin/ABP280 repeat Invasin_D3 PF09134.10 EKX54976.1 - 4.7e-09 36.4 5.6 0.00048 20.4 0.2 3.1 3 0 0 3 3 3 3 Invasin, domain 3 Big_1 PF02369.16 EKX54976.1 - 4.7e-05 23.3 5.9 0.076 13.0 0.3 4.0 3 2 0 3 3 3 2 Bacterial Ig-like domain (group 1) Herpes_IR6 PF06307.12 EKX54976.1 - 0.0011 18.6 0.0 1.5 8.4 0.0 2.1 2 0 0 2 2 2 2 Herpesvirus IR6 protein DUF5060 PF16586.5 EKX54976.1 - 0.11 12.9 0.6 63 4.1 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5060) Bact_lectin PF18483.1 EKX54976.1 - 0.94 9.5 4.7 9.2 6.2 0.5 2.3 2 0 0 2 2 2 0 Bacterial lectin Neurexophilin PF06312.12 EKX54976.1 - 1.4 8.3 5.0 1.5 8.2 0.7 2.8 3 1 1 4 4 4 0 Neurexophilin YHYH PF14240.6 EKX54980.1 - 2.5e-11 43.9 0.4 6.2e-05 23.0 0.0 3.0 1 1 2 3 3 3 2 YHYH protein WW PF00397.26 EKX54980.1 - 2.2e-08 34.0 2.9 2.6e-08 33.8 1.7 1.8 2 0 0 2 2 2 1 WW domain Ion_trans_2 PF07885.16 EKX54981.1 - 3.7e-14 52.4 5.1 8.4e-14 51.3 5.0 1.7 1 1 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EKX54981.1 - 3.2e-08 33.1 3.3 6.2e-08 32.2 3.3 1.4 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 EKX54981.1 - 4.9e-08 32.9 0.0 1.1e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain IRK PF01007.20 EKX54981.1 - 0.006 16.4 2.4 0.006 16.4 2.4 1.9 2 0 0 2 2 2 1 Inward rectifier potassium channel transmembrane domain CCDC53 PF10152.9 EKX54981.1 - 0.14 12.6 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF4149 PF13664.6 EKX54981.1 - 0.15 12.4 0.5 0.51 10.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) WD40 PF00400.32 EKX54982.1 - 2.3e-37 126.3 26.4 1.5e-06 28.8 0.4 9.1 9 0 0 9 9 9 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX54982.1 - 1.2e-20 73.6 2.1 2e-06 28.0 0.1 6.0 2 1 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EKX54982.1 - 1e-05 24.4 2.9 7e-05 21.7 0.6 2.7 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EKX54982.1 - 1.8e-05 23.9 0.8 0.19 10.7 0.1 4.3 3 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EKX54982.1 - 0.00037 19.9 0.0 0.3 10.4 0.0 3.0 2 1 0 2 2 2 2 WD40-like domain Nbas_N PF15492.6 EKX54982.1 - 0.0033 16.8 1.3 1.5 8.1 0.1 3.4 3 1 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 EKX54982.1 - 0.046 12.5 0.4 8.5 5.0 0.0 2.9 2 1 1 3 3 3 0 Nup133 N terminal like Hira PF07569.11 EKX54982.1 - 0.11 12.2 2.0 6.8 6.3 0.1 3.1 2 2 1 3 3 3 0 TUP1-like enhancer of split PD40 PF07676.12 EKX54982.1 - 0.13 12.2 0.3 2 8.4 0.0 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat TMEM18 PF14770.6 EKX54984.1 - 3e-38 130.5 6.9 3.3e-38 130.3 6.9 1.0 1 0 0 1 1 1 1 Transmembrane protein 18 SHR3_chaperone PF08229.11 EKX54984.1 - 0.0046 16.0 0.4 0.0069 15.4 0.4 1.3 1 0 0 1 1 1 1 ER membrane protein SH3 DUF1538 PF07556.11 EKX54984.1 - 0.0049 16.2 0.6 0.0066 15.8 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1538) DUF4131 PF13567.6 EKX54984.1 - 0.033 13.8 2.7 0.038 13.6 2.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) TraQ PF09679.10 EKX54984.1 - 0.065 13.2 1.8 3.1 7.8 0.1 2.2 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) DAGK_prokar PF01219.19 EKX54984.1 - 0.91 9.4 6.2 0.13 12.1 1.4 1.8 1 1 1 2 2 2 0 Prokaryotic diacylglycerol kinase Bac_rhodopsin PF01036.18 EKX54985.1 - 1.9e-20 73.4 10.1 1e-19 71.0 10.1 2.0 1 1 0 1 1 1 1 Bacteriorhodopsin-like protein DUF3400 PF11880.8 EKX54986.1 - 0.16 11.5 0.1 0.4 10.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3400) NHL PF01436.21 EKX54988.1 - 5.6e-15 54.5 8.2 6.3e-07 29.1 0.2 5.8 6 0 0 6 6 6 3 NHL repeat SGL PF08450.12 EKX54988.1 - 0.0018 17.9 0.0 0.0044 16.6 0.0 1.6 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Phytase-like PF13449.6 EKX54988.1 - 0.11 12.5 0.0 0.34 10.8 0.0 1.6 1 1 1 2 2 2 0 Esterase-like activity of phytase IQ PF00612.27 EKX54989.1 - 0.5 10.3 3.2 1.5 8.8 0.2 2.8 2 0 0 2 2 2 0 IQ calmodulin-binding motif LRR_8 PF13855.6 EKX54990.1 - 6e-20 70.8 21.0 1e-10 41.2 5.3 3.3 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EKX54990.1 - 9.1e-13 48.2 34.3 3.5e-05 24.1 0.9 4.3 1 1 6 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX54990.1 - 0.00027 21.1 19.2 0.37 11.5 1.3 6.0 5 1 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.6 EKX54990.1 - 1.3 9.2 18.1 20 5.5 0.4 5.9 6 0 0 6 6 6 0 Leucine Rich repeat LRR_8 PF13855.6 EKX54991.1 - 7.5e-25 86.5 18.8 2.5e-10 40.0 3.0 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EKX54991.1 - 3.9e-16 58.9 10.2 4.9e-06 26.8 0.7 3.5 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EKX54991.1 - 3.1e-08 33.0 9.1 0.0096 15.9 0.3 5.0 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 EKX54991.1 - 3.9e-05 23.6 7.8 1.6 9.6 0.1 4.6 3 2 0 3 3 3 2 Leucine Rich Repeat LRR_9 PF14580.6 EKX54991.1 - 0.00011 21.8 0.3 0.00023 20.7 0.3 1.5 1 1 0 1 1 1 1 Leucine-rich repeat DUF4571 PF15137.6 EKX54991.1 - 0.012 15.2 0.0 0.04 13.6 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4571) LRR_8 PF13855.6 EKX54992.1 - 7.3e-14 51.3 7.2 5.3e-08 32.5 1.0 2.1 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EKX54992.1 - 1.1e-12 47.9 11.4 1.1e-06 28.9 1.2 2.7 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX54992.1 - 0.079 13.6 7.4 85 4.3 4.0 4.1 2 1 0 2 2 2 0 Leucine Rich Repeat LRR_8 PF13855.6 EKX54993.1 - 3.5e-50 167.6 60.5 2.8e-09 36.6 4.2 8.8 2 1 9 11 11 11 11 Leucine rich repeat LRR_4 PF12799.7 EKX54993.1 - 5.2e-43 144.3 70.6 2.2e-08 34.3 1.1 10.9 2 2 10 14 14 14 14 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EKX54993.1 - 5.1e-14 52.2 34.2 0.0014 18.1 3.6 6.6 1 1 5 6 6 6 6 Leucine-rich repeat LRR_5 PF13306.6 EKX54993.1 - 3e-05 24.0 8.7 0.044 13.8 1.8 3.9 2 1 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EKX54993.1 - 0.0012 19.1 53.0 1.2 9.9 0.8 13.5 13 4 1 14 14 14 4 Leucine Rich Repeat RsmF_methylt_CI PF17126.5 EKX54993.1 - 0.011 15.7 0.2 6.4 6.9 0.0 4.7 4 0 0 4 4 4 0 RsmF rRNA methyltransferase first C-terminal domain LEDGF PF11467.8 EKX54993.1 - 0.63 9.7 5.8 17 5.0 0.1 3.9 4 1 1 5 5 5 0 Lens epithelium-derived growth factor (LEDGF) HhH-GPD PF00730.25 EKX54994.1 - 5.3e-16 59.0 0.0 6.5e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EKX54994.1 - 3e-08 33.1 0.0 7.1e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EKX54994.1 - 0.0092 16.6 0.3 0.11 13.1 0.1 2.6 2 1 0 2 2 2 1 Helix-hairpin-helix domain SAM_LFY PF01698.16 EKX54994.1 - 0.011 15.7 0.1 0.024 14.6 0.1 1.6 2 0 0 2 2 2 0 Floricaula / Leafy protein SAM domain Leu_zip PF15294.6 EKX54994.1 - 0.014 15.0 1.3 0.018 14.6 1.3 1.1 1 0 0 1 1 1 0 Leucine zipper SAM_KSR1 PF13543.6 EKX54994.1 - 0.05 13.7 0.2 0.072 13.2 0.2 1.2 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 Alpha-amylase PF00128.24 EKX54995.1 - 8.9e-17 61.7 0.1 1.8e-16 60.6 0.1 1.5 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Siah-Interact_N PF09032.11 EKX54995.1 - 0.0021 18.3 0.9 0.0045 17.3 0.9 1.5 1 0 0 1 1 1 1 Siah interacting protein, N terminal PAP_central PF04928.17 EKX54995.1 - 0.0093 15.0 0.0 0.02 13.9 0.0 1.6 1 1 0 1 1 1 1 Poly(A) polymerase central domain Glyco_hydro_114 PF03537.13 EKX54995.1 - 0.019 14.3 0.0 0.089 12.1 0.0 2.1 3 0 0 3 3 3 0 Glycoside-hydrolase family GH114 hDGE_amylase PF14701.6 EKX54995.1 - 0.077 12.1 0.1 0.077 12.1 0.1 1.6 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain COX6B PF02297.17 EKX54996.1 - 7.8e-17 61.3 4.0 9.1e-17 61.1 4.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb AAA_16 PF13191.6 EKX54997.1 - 1.2e-08 35.6 0.0 4.6e-07 30.4 0.0 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EKX54997.1 - 8.8e-07 29.3 0.0 1.9e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EKX54997.1 - 0.013 14.7 0.0 0.029 13.5 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 EKX54997.1 - 0.074 13.0 0.0 0.25 11.3 0.0 1.9 1 1 0 1 1 1 0 NACHT domain AAA PF00004.29 EKX54997.1 - 0.15 12.5 0.0 0.61 10.5 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EKX54997.1 - 0.18 11.9 0.0 0.53 10.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain SURF2 PF05477.11 EKX54998.1 - 0.1 12.3 1.1 0.12 12.0 1.1 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF1770 PF08589.10 EKX54998.1 - 0.49 11.4 2.3 0.94 10.5 1.1 1.9 1 1 1 2 2 2 0 Fungal protein of unknown function (DUF1770) KLRAQ PF10205.9 EKX54999.1 - 0.0017 18.5 6.2 0.0017 18.5 6.2 2.3 2 1 0 2 2 2 1 Predicted coiled-coil domain-containing protein TMEM192 PF14802.6 EKX54999.1 - 0.025 13.7 2.2 0.025 13.7 2.2 1.6 2 0 0 2 2 2 0 TMEM192 family SPOC PF07744.13 EKX55001.1 - 1.8e-11 44.2 0.0 4.3e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 SPOC domain PWWP PF00855.17 EKX55001.1 - 3.8e-09 36.8 0.1 1.6e-08 34.8 0.1 2.2 1 0 0 1 1 1 1 PWWP domain TFIIS_M PF07500.14 EKX55001.1 - 1.4e-08 35.2 0.0 6.8e-08 33.0 0.0 2.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain zf-CW PF07496.15 EKX55001.1 - 2.1e-08 34.0 3.7 4.4e-08 33.0 3.7 1.6 1 0 0 1 1 1 1 CW-type Zinc Finger Equine_IAV_S2 PF06502.11 EKX55001.1 - 4 7.6 5.9 13 5.9 5.9 1.9 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein Macoilin PF09726.9 EKX55001.1 - 5 5.6 60.1 0.033 12.7 23.6 3.3 3 0 0 3 3 3 0 Macoilin family PLU-1 PF08429.11 EKX55002.1 - 3e-17 62.8 11.1 6.9e-17 61.6 8.9 2.0 1 1 1 2 2 2 2 PLU-1-like protein DivIC PF04977.15 EKX55003.1 - 0.24 11.2 2.7 0.61 9.9 0.1 2.1 1 1 0 2 2 2 0 Septum formation initiator Vta1 PF04652.16 EKX55005.1 - 2.4e-31 108.6 2.7 3.8e-31 108.0 2.7 1.2 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 EKX55005.1 - 1e-15 57.1 0.2 2.3e-15 56.0 0.2 1.6 1 0 0 1 1 1 1 Vta1 C-terminal domain Spc7 PF08317.11 EKX55008.1 - 0.00011 21.2 7.8 0.00011 21.2 7.8 4.1 2 1 2 4 4 4 1 Spc7 kinetochore protein GAS PF13851.6 EKX55008.1 - 0.0034 16.8 8.4 0.0034 16.8 8.4 4.4 2 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 EKX55008.1 - 0.03 14.3 1.2 0.03 14.3 1.2 4.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Bacillus_HBL PF05791.11 EKX55008.1 - 0.05 13.4 6.4 0.029 14.2 1.7 2.9 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) OEP PF02321.18 EKX55008.1 - 0.34 10.7 17.6 0.11 12.3 10.7 2.5 2 0 0 2 2 2 0 Outer membrane efflux protein NPV_P10 PF05531.12 EKX55008.1 - 0.78 10.2 10.1 2.5 8.6 0.8 4.3 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein ABC_tran_CTD PF16326.5 EKX55008.1 - 0.8 10.0 18.4 0.095 13.0 0.6 4.7 2 1 2 4 4 4 0 ABC transporter C-terminal domain MbeB_N PF04837.12 EKX55008.1 - 1.1 9.6 7.0 28 5.1 0.0 4.5 3 0 0 3 3 3 0 MbeB-like, N-term conserved region Baculo_PEP_C PF04513.12 EKX55008.1 - 2.6 8.1 10.0 10 6.2 2.8 3.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TACC_C PF05010.14 EKX55008.1 - 6.9 6.4 24.3 0.61 9.8 11.5 3.9 3 1 1 4 4 4 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF4665 PF15679.5 EKX55008.1 - 7 7.3 10.4 3.2 8.4 0.4 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4665) Hemagglutinin PF00509.18 EKX55008.1 - 8.3 4.7 9.3 0.27 9.6 1.2 2.0 1 1 1 2 2 2 0 Haemagglutinin G-patch PF01585.23 EKX55009.1 - 1.2e-13 50.6 0.0 2.4e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EKX55009.1 - 0.00025 21.1 2.5 0.00028 20.9 0.1 2.2 2 0 0 2 2 2 1 G-patch domain TMEM40 PF15817.5 EKX55009.1 - 0.19 11.5 2.7 3.8 7.3 1.8 2.2 2 0 0 2 2 2 0 Transmembrane protein 40 family Nckap1 PF09735.9 EKX55010.1 - 8.1e-74 249.3 3.9 3.2e-55 187.7 5.9 2.1 1 1 1 2 2 2 2 Membrane-associated apoptosis protein Raptor_N PF14538.6 EKX55010.1 - 0.055 13.4 3.6 2.8 7.9 0.0 3.7 4 0 0 4 4 4 0 Raptor N-terminal CASPase like domain Hormone_2 PF00123.20 EKX55011.1 - 0.11 12.4 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 Peptide hormone Med10 PF09748.9 EKX55012.1 - 1.6e-16 60.4 0.0 2.3e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex RSS_P20 PF11757.8 EKX55012.1 - 0.17 12.3 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like N-terminal domain Mito_carr PF00153.27 EKX55013.1 - 5e-65 215.5 1.7 9e-25 86.4 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EKX55013.1 - 7.8 5.6 7.6 18 4.3 0.1 3.4 4 1 1 5 5 5 0 Gammaproteobacterial serine protease DUF410 PF04190.13 EKX55014.1 - 7.2e-34 117.7 0.3 9.7e-34 117.3 0.2 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF410) TPR_12 PF13424.6 EKX55014.1 - 0.041 14.2 2.1 2.1 8.7 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat LXG PF04740.12 EKX55015.1 - 0.028 14.2 0.6 0.16 11.6 0.1 2.4 1 1 2 3 3 3 0 LXG domain of WXG superfamily DUF3450 PF11932.8 EKX55015.1 - 0.17 11.2 0.8 0.25 10.6 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Pox_A_type_inc PF04508.12 EKX55015.1 - 0.55 10.2 3.1 1.2 9.1 3.1 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat HTH_Tnp_Tc5 PF03221.16 EKX55016.1 - 5.5e-06 26.3 0.1 1.1e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 EKX55016.1 - 0.0013 18.3 0.0 0.0059 16.2 0.0 2.0 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_3 PF01381.22 EKX55016.1 - 0.059 13.4 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix HTH_38 PF13936.6 EKX55016.1 - 0.28 11.0 3.3 0.5 10.2 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_Tc5 PF03221.16 EKX55017.1 - 4.7e-06 26.5 0.1 9.7e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 EKX55017.1 - 0.029 14.0 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain HTH_3 PF01381.22 EKX55017.1 - 0.19 11.8 0.2 0.46 10.6 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix HTH_Tnp_Tc5 PF03221.16 EKX55018.1 - 1.8e-06 27.9 0.1 3.4e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 EKX55018.1 - 0.002 17.7 0.0 0.0042 16.7 0.0 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_3 PF01381.22 EKX55018.1 - 0.074 13.1 0.4 0.15 12.1 0.1 1.6 2 0 0 2 2 2 0 Helix-turn-helix HTH_38 PF13936.6 EKX55018.1 - 0.45 10.3 4.3 0.49 10.2 0.2 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain Methyltr_RsmB-F PF01189.17 EKX55019.1 - 1.7e-36 125.8 0.0 1.7e-33 116.0 0.0 3.1 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EKX55019.1 - 0.16 12.1 0.0 0.41 10.7 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Glyco_transf_24 PF18404.1 EKX55021.1 - 1.1e-144 480.8 3.7 1.9e-144 480.0 3.7 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 EKX55021.1 - 6e-41 141.1 0.1 6e-41 141.1 0.1 2.4 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 EKX55021.1 - 2.1e-38 132.1 0.4 1.8e-37 129.1 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 EKX55021.1 - 9.9e-34 116.2 1.9 4.6e-33 114.0 0.1 2.7 3 0 0 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 EKX55021.1 - 6.1e-23 81.0 0.0 1.5e-22 79.8 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_15 PF18403.1 EKX55021.1 - 6.4e-16 58.9 2.9 7e-13 49.0 0.4 3.3 3 0 0 3 3 3 2 Thioredoxin-like domain Glyco_transf_8 PF01501.20 EKX55021.1 - 2.4e-05 24.0 0.1 5.4e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 8 FAD_binding_3 PF01494.19 EKX55022.1 - 1.3e-07 31.2 0.0 0.002 17.5 0.1 2.6 2 1 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 EKX55022.1 - 2.5e-05 23.7 0.0 0.0001 21.6 0.0 1.9 1 1 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.14 EKX55022.1 - 0.0028 16.6 0.0 2.1 7.1 0.0 2.3 2 1 0 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 EKX55022.1 - 0.0092 15.2 0.1 0.02 14.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EKX55022.1 - 0.01 15.8 0.0 2.3 8.2 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.24 EKX55022.1 - 0.012 15.2 0.0 3.7 7.0 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EKX55022.1 - 0.026 14.7 0.0 0.057 13.7 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Arg_decarbox_C PF17944.1 EKX55023.1 - 0.2 12.3 0.1 5.3 7.7 0.0 2.1 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension tRNA_synthFbeta PF17759.1 EKX55024.1 - 0.06 12.8 0.4 1.3 8.4 0.1 2.3 1 1 1 2 2 2 0 Phenylalanyl tRNA synthetase beta chain CLM domain Topoisom_bac PF01131.20 EKX55025.1 - 4.2e-116 388.3 0.0 5.2e-116 388.1 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EKX55025.1 - 9.7e-16 57.9 0.0 1.8e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Toprim domain DDE_Tnp_4 PF13359.6 EKX55026.1 - 5e-07 29.5 0.0 7.1e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EKX55026.1 - 0.22 11.1 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain Peptidase_S41 PF03572.18 EKX55027.1 - 4.4e-36 123.9 0.0 7e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 EKX55027.1 - 8e-10 38.4 0.2 2e-09 37.1 0.2 1.8 1 1 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX55027.1 - 8.3e-08 32.5 0.0 1.7e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX55027.1 - 9.1e-05 22.7 0.1 0.00018 21.8 0.1 1.5 1 0 0 1 1 1 1 PDZ domain DUF390 PF04094.14 EKX55028.1 - 0.15 10.3 3.0 0.2 9.9 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) ERp29 PF07749.12 EKX55029.1 - 2.9e-27 95.4 5.0 5e-27 94.6 5.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain ERp29_N PF07912.13 EKX55029.1 - 4.2e-26 91.6 0.1 7.7e-26 90.7 0.1 1.4 1 0 0 1 1 1 1 ERp29, N-terminal domain DnaB_bind PF10410.9 EKX55029.1 - 0.038 14.2 0.4 0.31 11.3 0.1 2.3 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase DUF4586 PF15239.6 EKX55031.1 - 1.9e-49 169.5 14.5 2.6e-49 169.0 14.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) zf-C2H2_4 PF13894.6 EKX55032.1 - 0.0048 17.6 18.8 0.82 10.7 0.3 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EKX55032.1 - 0.0089 16.3 10.8 0.014 15.7 10.5 1.5 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2 PF00096.26 EKX55032.1 - 0.022 15.2 19.3 0.066 13.7 3.6 3.5 3 1 0 3 3 3 0 Zinc finger, C2H2 type Prim_Zn_Ribbon PF08273.12 EKX55032.1 - 0.038 14.3 0.2 0.038 14.3 0.2 1.8 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DUF4729 PF15866.5 EKX55032.1 - 1 8.6 8.0 1.7 7.9 2.4 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4729) zf-C2H2_aberr PF17017.5 EKX55032.1 - 2.8 8.1 7.4 6.9 6.8 0.2 2.8 1 1 2 3 3 3 0 Aberrant zinc-finger DUF629 PF04780.12 EKX55032.1 - 7.8 4.9 11.3 2.9 6.3 2.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF629) Ala_racemase_N PF01168.20 EKX55033.1 - 2.5e-23 82.9 0.0 3.1e-23 82.6 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain WD40 PF00400.32 EKX55034.1 - 1.1e-12 48.2 7.5 0.00079 20.2 1.1 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX55034.1 - 7.1e-05 23.0 0.3 0.21 11.9 0.0 4.0 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Mito_carr PF00153.27 EKX55035.1 - 2.1e-33 114.1 10.4 2.1e-14 53.2 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein XendoU PF09412.10 EKX55037.1 - 3.2e-88 295.4 0.0 3.7e-88 295.2 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease XendoU Fucose_iso_N2 PF07882.12 EKX55037.1 - 0.081 12.5 0.3 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 L-fucose isomerase, second N-terminal domain MORN PF02493.20 EKX55038.1 - 6.6e-30 101.2 45.2 3.8e-07 29.6 2.0 8.6 8 1 0 8 8 8 7 MORN repeat CPSF_A PF03178.15 EKX55039.1 - 1.1e-69 235.3 0.0 2.2e-69 234.3 0.0 1.5 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 EKX55039.1 - 1.1e-28 100.1 0.0 2.2e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term LRR_6 PF13516.6 EKX55039.1 - 2.4e-05 24.0 4.1 0.17 12.0 0.0 3.9 3 0 0 3 3 3 2 Leucine Rich repeat zf-CCHC_6 PF15288.6 EKX55039.1 - 0.2 11.5 1.0 0.59 10.0 1.0 1.8 1 0 0 1 1 1 0 Zinc knuckle ETX_MTX2 PF03318.13 EKX55039.1 - 0.66 9.7 3.3 1.3 8.8 2.9 1.6 2 0 0 2 2 2 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Peptidase_C1 PF00112.23 EKX55040.1 - 2.9e-76 256.4 0.6 4.7e-76 255.7 0.6 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EKX55040.1 - 1.1e-09 38.5 2.1 1.1e-09 38.5 2.1 1.7 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EKX55040.1 - 0.004 16.0 0.8 1.2 7.8 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family TTSSLRR PF12468.8 EKX55040.1 - 0.17 12.2 2.2 0.34 11.2 2.2 1.5 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein MFS_1 PF07690.16 EKX55041.1 - 3.5e-29 101.8 21.6 3.4e-26 92.0 19.4 3.2 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EKX55041.1 - 8.2e-07 28.2 1.3 0.013 14.4 0.3 2.7 3 1 0 3 3 3 2 MFS_1 like family Sugar_tr PF00083.24 EKX55041.1 - 0.00033 19.7 1.2 0.00033 19.7 1.2 3.1 3 1 1 4 4 4 1 Sugar (and other) transporter DUF2583 PF10762.9 EKX55041.1 - 1.6 9.2 5.6 4.1 7.9 0.1 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF2583) OATP PF03137.20 EKX55041.1 - 5.7 5.1 16.3 0.36 9.1 0.7 3.4 4 0 0 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_A22B PF04258.13 EKX55042.1 - 4e-66 223.4 20.7 5.8e-66 222.9 20.7 1.2 1 0 0 1 1 1 1 Signal peptide peptidase D123 PF07065.14 EKX55043.1 - 7.6e-93 311.0 0.3 1e-92 310.6 0.3 1.1 1 0 0 1 1 1 1 D123 CENP-B_dimeris PF09026.10 EKX55043.1 - 4.8 7.6 6.4 9.5 6.7 6.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2207 PF09972.9 EKX55044.1 - 0.0038 16.0 1.4 0.0065 15.3 0.0 1.9 1 1 1 2 2 2 1 Predicted membrane protein (DUF2207) DUF2299 PF10061.9 EKX55044.1 - 0.06 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) DUF373 PF04123.13 EKX55044.1 - 0.69 9.3 3.4 0.37 10.2 1.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF373) FtsK_4TM PF13491.6 EKX55044.1 - 1.9 8.1 9.1 0.094 12.4 3.4 1.6 2 0 0 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE IQ PF00612.27 EKX55045.1 - 4.7e-19 66.3 57.3 0.0014 18.3 0.3 12.1 12 0 0 12 12 12 10 IQ calmodulin-binding motif YccF PF03733.13 EKX55048.1 - 5.7e-21 75.0 32.0 3.8e-11 43.5 14.6 2.1 2 0 0 2 2 2 2 Inner membrane component domain Kinesin PF00225.23 EKX55049.1 - 1.3e-28 99.9 0.0 1.2e-18 67.2 0.0 2.5 2 1 1 3 3 3 2 Kinesin motor domain DUF547 PF04784.14 EKX55049.1 - 1.1e-24 86.8 0.0 1.5e-23 83.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF547 Microtub_bd PF16796.5 EKX55049.1 - 2.6e-08 33.9 0.0 6.2e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding DEP PF00610.21 EKX55049.1 - 1.7e-07 31.2 0.5 3.4e-06 27.0 0.5 2.5 1 1 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Guanylate_cyc PF00211.20 EKX55050.1 - 3.1e-44 150.8 0.0 3.5e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain SpoVR PF04293.13 EKX55050.1 - 0.13 11.0 0.0 0.15 10.7 0.0 1.0 1 0 0 1 1 1 0 SpoVR like protein Pkinase_Tyr PF07714.17 EKX55051.1 - 6.3e-49 166.6 0.0 8.3e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX55051.1 - 2.2e-48 164.9 0.0 3e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EKX55051.1 - 0.0023 17.5 0.0 0.0062 16.2 0.0 1.6 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 EKX55051.1 - 0.0033 16.8 0.0 0.0056 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX55051.1 - 0.015 15.2 0.5 0.18 11.7 0.1 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EKX55052.1 - 6.1e-49 166.6 0.0 7.9e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EKX55052.1 - 2.2e-48 164.9 0.0 3e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EKX55052.1 - 0.0023 17.5 0.0 0.0062 16.2 0.0 1.6 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 EKX55052.1 - 0.0033 16.8 0.0 0.0056 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EKX55052.1 - 0.015 15.2 0.9 0.18 11.7 0.1 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Guanylate_cyc PF00211.20 EKX55053.1 - 2.2e-44 151.3 0.0 2.5e-44 151.1 0.0 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Glyco_transf_41 PF13844.6 EKX55054.1 - 5.4e-32 110.8 0.0 2.2e-25 89.0 0.0 2.4 2 1 1 3 3 3 2 Glycosyl transferase family 41 TPR_2 PF07719.17 EKX55054.1 - 0.0046 17.0 0.0 0.015 15.3 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX55054.1 - 0.019 14.8 0.0 0.047 13.5 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Collagen PF01391.18 EKX55054.1 - 0.028 14.2 16.4 0.062 13.1 16.4 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) DnaJ PF00226.31 EKX55056.1 - 1.4e-29 101.9 3.0 2.1e-29 101.4 3.0 1.3 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 EKX55056.1 - 0.084 12.8 0.0 0.21 11.6 0.0 1.6 1 1 0 1 1 1 0 A repeated domain in UCH-protein F-box-like PF12937.7 EKX55057.1 - 0.00014 21.6 1.0 0.0004 20.2 1.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EKX55057.1 - 0.002 18.0 0.0 0.0053 16.6 0.0 1.8 1 0 0 1 1 1 1 F-box domain DUF1676 PF07898.13 EKX55058.1 - 0.011 15.7 1.0 0.011 15.7 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Rubis-subs-bind PF09273.11 EKX55058.1 - 0.077 13.7 0.4 0.38 11.4 0.0 2.4 2 0 0 2 2 2 0 Rubisco LSMT substrate-binding Amnionless PF14828.6 EKX55058.1 - 0.12 11.1 0.5 0.2 10.4 0.5 1.3 1 0 0 1 1 1 0 Amnionless Claudin_2 PF13903.6 EKX55058.1 - 0.13 12.0 2.0 0.32 10.7 2.0 1.5 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction PRT_C PF08372.10 EKX55058.1 - 0.36 10.6 5.0 0.75 9.5 5.0 1.4 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal Orf78 PF06024.12 EKX55058.1 - 0.52 10.7 6.3 0.093 13.0 1.8 2.1 2 0 0 2 2 2 0 Orf78 (ac78) T2SSF PF00482.23 EKX55058.1 - 1.5 8.8 10.1 0.77 9.7 6.2 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F GPI2 PF06432.11 EKX55058.1 - 9.9 5.5 8.6 28 4.0 9.1 1.4 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase NPV_P10 PF05531.12 EKX55059.1 - 0.1 13.1 0.3 0.1 13.1 0.3 3.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Cas_DxTHG PF09455.10 EKX55059.1 - 0.86 9.1 13.7 0.7 9.4 12.1 1.7 1 1 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family FlaC_arch PF05377.11 EKX55059.1 - 1.4 9.4 24.6 0.14 12.6 1.3 5.3 5 1 1 6 6 6 0 Flagella accessory protein C (FlaC) HAP1_N PF04849.13 EKX55059.1 - 3.9 6.6 48.8 4.3 6.4 4.0 3.5 1 1 2 3 3 3 0 HAP1 N-terminal conserved region DUF4200 PF13863.6 EKX55059.1 - 6.4 7.2 50.7 1.8 9.0 6.4 5.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4200) CH PF00307.31 EKX55061.1 - 3.3e-19 69.1 0.0 3.1e-09 37.0 0.0 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain zf-C3HC4_3 PF13920.6 EKX55061.1 - 4.9e-05 23.1 4.1 0.00014 21.6 4.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EKX55061.1 - 0.00013 21.9 1.3 0.00054 19.9 1.3 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EKX55061.1 - 0.0002 21.2 2.9 0.00055 19.8 2.9 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EKX55061.1 - 0.00035 20.4 5.0 0.00065 19.5 2.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EKX55061.1 - 0.0006 19.6 4.7 0.0014 18.5 4.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EKX55061.1 - 0.00094 19.3 5.8 0.0013 18.8 3.9 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EKX55061.1 - 0.0011 19.2 5.0 0.0011 19.2 5.0 2.8 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 EKX55061.1 - 0.023 14.5 4.4 0.09 12.6 4.4 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EKX55061.1 - 0.057 13.7 6.6 0.72 10.2 3.3 2.6 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 EKX55061.1 - 0.2 11.5 1.6 0.84 9.5 1.6 2.0 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf_CCCH_4 PF18345.1 EKX55062.1 - 1.6e-06 27.9 2.4 6.1e-06 26.1 2.4 2.1 1 0 0 1 1 1 1 Zinc finger domain tRNA_anti-codon PF01336.25 EKX55062.1 - 0.00017 21.5 0.1 0.00031 20.7 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain zf-CCCH_4 PF18044.1 EKX55062.1 - 0.0099 15.7 0.7 0.026 14.3 0.3 2.0 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH PF00642.24 EKX55062.1 - 0.072 13.0 0.1 0.072 13.0 0.1 2.3 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 EKX55062.1 - 0.1 13.1 1.7 0.17 12.4 0.2 2.2 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DUF4131 PF13567.6 EKX55062.1 - 0.11 12.1 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) CH PF00307.31 EKX55063.1 - 3e-08 33.8 0.0 3.8e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain zf_CCCH_4 PF18345.1 EKX55064.1 - 4.1e-06 26.7 2.4 4.1e-06 26.7 2.4 2.1 3 0 0 3 3 3 1 Zinc finger domain tRNA_anti-codon PF01336.25 EKX55064.1 - 0.0001 22.2 0.1 0.00016 21.6 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain zf-CCCH_4 PF18044.1 EKX55064.1 - 0.0063 16.3 0.7 0.017 14.9 0.3 2.0 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH PF00642.24 EKX55064.1 - 0.047 13.6 0.1 0.047 13.6 0.1 2.4 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 EKX55064.1 - 0.065 13.7 1.7 0.11 13.0 0.2 2.1 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DUF4131 PF13567.6 EKX55064.1 - 0.067 12.8 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) zf-CCCH_3 PF15663.5 EKX55064.1 - 0.21 11.8 2.0 3 8.1 0.9 2.3 1 1 1 2 2 2 0 Zinc-finger containing family DSPc PF00782.20 EKX55065.1 - 6.3e-12 45.5 0.3 1.2e-11 44.6 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX55065.1 - 3.8e-05 23.4 0.0 6.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX55065.1 - 0.00031 20.9 0.0 0.00051 20.2 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.12 EKX55065.1 - 0.061 13.0 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Init_tRNA_PT PF04179.12 EKX55065.1 - 0.11 12.8 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain WD40 PF00400.32 EKX55066.1 - 1.6e-06 28.7 0.5 2.3 9.3 0.0 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat RNase_T PF00929.24 EKX55067.1 - 3.3e-16 60.3 0.0 1.1e-15 58.6 0.0 1.8 1 1 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EKX55067.1 - 0.034 13.9 0.0 0.27 10.9 0.0 2.4 1 1 0 1 1 1 0 3'-5' exonuclease ASF1_hist_chap PF04729.13 EKX55068.1 - 2.3e-47 160.8 0.0 2.8e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone adh_short PF00106.25 EKX55069.1 - 5.4e-31 107.6 0.1 2.1e-30 105.7 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EKX55069.1 - 4.4e-20 72.3 0.0 1.7e-19 70.4 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX55069.1 - 6.2e-09 36.0 0.0 9.3e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EKX55069.1 - 0.00026 20.6 0.0 0.00034 20.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EKX55069.1 - 0.00076 19.4 0.0 0.0014 18.5 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EKX55069.1 - 0.002 17.6 0.0 0.0026 17.2 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF2188 PF09954.9 EKX55069.1 - 0.14 12.3 0.0 0.97 9.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) IMPDH PF00478.25 EKX55070.1 - 0.053 12.5 0.0 0.078 12.0 0.0 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain cNMP_binding PF00027.29 EKX55071.1 - 5.3e-08 32.8 0.0 1.8e-05 24.8 0.0 2.5 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain AAA_25 PF13481.6 EKX55075.1 - 7.9e-06 25.6 0.0 1.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EKX55075.1 - 0.0035 17.6 5.2 0.11 12.8 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_11 PF13086.6 EKX55075.1 - 0.0045 16.8 0.0 0.0045 16.8 0.0 3.2 2 1 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 EKX55075.1 - 0.0082 16.5 0.1 0.03 14.7 0.1 2.0 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 EKX55075.1 - 0.015 15.0 0.0 0.015 15.0 0.0 2.4 3 0 0 3 3 3 0 AAA domain DUF2877 PF11392.8 EKX55075.1 - 0.024 15.3 4.3 2.5 8.8 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2877) AAA PF00004.29 EKX55075.1 - 0.032 14.7 0.0 0.1 13.0 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EKX55075.1 - 0.043 14.1 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EKX55075.1 - 0.044 13.3 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 EKX55075.1 - 0.045 13.7 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EKX55075.1 - 0.076 13.4 0.0 0.076 13.4 0.0 2.5 2 2 0 2 2 2 0 AAA ATPase domain DUF1654 PF07867.11 EKX55075.1 - 0.13 12.0 5.4 6.2 6.6 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) FtsK_SpoIIIE PF01580.18 EKX55075.1 - 0.14 11.5 0.0 0.14 11.5 0.0 2.4 2 1 1 3 3 3 0 FtsK/SpoIIIE family ABC_tran PF00005.27 EKX55075.1 - 0.16 12.5 0.0 0.16 12.5 0.0 3.0 2 1 0 2 2 1 0 ABC transporter DndE PF08870.11 EKX55075.1 - 0.24 11.7 8.4 1.8 8.9 1.1 2.4 1 1 1 2 2 2 0 DNA sulphur modification protein DndE MeaB PF03308.16 EKX55075.1 - 1.6 7.7 0.0 1.6 7.7 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 EKX55075.1 - 3.4 7.3 18.7 6.9 6.3 18.7 1.5 1 0 0 1 1 1 0 AAA ATPase domain V_ATPase_I PF01496.19 EKX55075.1 - 9.1 4.1 16.1 13 3.5 16.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPH PF13868.6 EKX55076.1 - 5.5e-64 215.9 156.4 5.5e-64 215.9 156.4 1.9 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Methyltransf_25 PF13649.6 EKX55077.1 - 6.9e-11 42.7 0.0 1.3e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EKX55077.1 - 2.7e-09 36.9 0.1 4.3e-09 36.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EKX55077.1 - 7.3e-08 33.0 0.0 1.6e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EKX55077.1 - 8.9e-08 32.1 0.0 1.4e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EKX55077.1 - 1.4e-07 31.1 0.1 2.1e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 EKX55077.1 - 9.4e-07 28.9 0.1 1.5e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EKX55077.1 - 1.4e-06 28.2 0.0 1.9e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EKX55077.1 - 4.7e-06 26.3 0.0 8.1e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 EKX55077.1 - 3.5e-05 22.9 0.0 5.4e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PRMT5 PF05185.16 EKX55077.1 - 5.9e-05 23.0 0.1 8.8e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase TehB PF03848.14 EKX55077.1 - 0.0001 21.8 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB NodS PF05401.11 EKX55077.1 - 0.0031 17.2 0.0 0.0049 16.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_12 PF08242.12 EKX55077.1 - 0.0052 17.5 0.0 0.01 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EKX55077.1 - 0.019 14.7 0.1 0.032 14.0 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF5321 PF17254.2 EKX55077.1 - 0.019 14.4 0.6 5.6 6.4 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5321) Methyltransf_24 PF13578.6 EKX55077.1 - 0.02 15.9 0.0 0.04 14.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PRMT5_C PF17286.2 EKX55077.1 - 0.073 12.9 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 PRMT5 oligomerisation domain Cons_hypoth95 PF03602.15 EKX55077.1 - 0.088 12.4 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_16 PF10294.9 EKX55077.1 - 0.092 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase FtsJ PF01728.19 EKX55077.1 - 0.094 12.8 0.1 0.18 11.9 0.1 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 EKX55077.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF667 PF05018.13 EKX55078.1 - 4.5e-94 313.4 1.8 5e-94 313.2 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Arm PF00514.23 EKX55079.1 - 4.9e-23 80.4 20.3 9.5e-06 25.5 0.1 6.3 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EKX55079.1 - 8.7e-11 42.1 6.9 6.5e-05 23.3 0.7 3.5 1 1 2 3 3 3 3 HEAT repeats HEAT PF02985.22 EKX55079.1 - 4.7e-09 35.7 9.2 0.016 15.4 0.2 4.8 4 0 0 4 4 4 3 HEAT repeat Cnd1 PF12717.7 EKX55079.1 - 3.4e-08 33.7 5.4 0.0019 18.3 0.4 2.1 1 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 KAP PF05804.12 EKX55079.1 - 8.8e-07 27.5 2.2 1.9e-06 26.3 2.2 1.5 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) Adaptin_N PF01602.20 EKX55079.1 - 1.5e-06 27.1 2.5 2.4e-06 26.4 2.4 1.4 1 1 0 1 1 1 1 Adaptin N terminal region Arm_2 PF04826.13 EKX55079.1 - 1.7e-05 24.4 6.1 0.00016 21.3 2.7 2.3 1 1 1 2 2 2 2 Armadillo-like Atx10homo_assoc PF09759.9 EKX55079.1 - 0.00051 20.0 1.1 0.0039 17.2 0.1 2.6 2 1 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain DUF3361 PF11841.8 EKX55079.1 - 0.001 19.0 4.8 0.0078 16.2 0.9 2.7 1 1 2 3 3 3 1 Domain of unknown function (DUF3361) HEAT_EZ PF13513.6 EKX55079.1 - 0.0016 18.9 10.3 1.9 9.1 0.9 4.5 3 2 1 4 4 4 2 HEAT-like repeat KicB PF03882.14 EKX55079.1 - 0.0034 17.6 1.0 0.77 10.0 0.1 2.5 1 1 1 2 2 2 2 MukF winged-helix domain Ric8 PF10165.9 EKX55079.1 - 0.017 14.2 0.4 0.045 12.8 0.1 1.8 1 1 1 2 2 2 0 Guanine nucleotide exchange factor synembryn HEAT_PBS PF03130.16 EKX55079.1 - 1 10.3 9.2 24 6.0 0.1 4.6 4 1 1 5 5 4 0 PBS lyase HEAT-like repeat Ank_5 PF13857.6 EKX55081.1 - 3.8e-06 27.1 0.1 7.3e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EKX55081.1 - 4e-05 24.1 0.2 0.018 15.6 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX55081.1 - 6.4e-05 23.5 0.0 0.00013 22.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EKX55081.1 - 0.00015 22.1 0.1 0.00043 20.6 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 EKX55081.1 - 0.0061 17.0 0.0 0.017 15.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Peptidase_S46 PF10459.9 EKX55081.1 - 0.54 8.8 33.6 0.7 8.5 33.6 1.1 1 0 0 1 1 1 0 Peptidase S46 CFAP91 PF14738.6 EKX55082.1 - 3.1e-45 153.9 7.8 3.1e-45 153.9 7.8 4.0 3 1 0 3 3 3 1 Cilia- and flagella-associated protein 91 DUF327 PF03885.13 EKX55082.1 - 0.035 14.1 0.7 0.035 14.1 0.7 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF327) Ank_5 PF13857.6 EKX55084.1 - 9e-08 32.3 0.0 2.4e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX55084.1 - 3.7e-06 27.4 0.0 1.3e-05 25.7 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX55084.1 - 0.00013 22.1 0.0 0.00049 20.3 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 EKX55084.1 - 0.0017 18.9 0.1 0.0039 17.7 0.0 1.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EKX55084.1 - 0.0065 16.9 0.0 0.016 15.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat DUF3708 PF12501.8 EKX55086.1 - 0.35 10.6 5.2 0.24 11.2 0.4 2.5 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter FtsJ PF01728.19 EKX55087.1 - 0.00015 21.9 0.0 0.00021 21.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Pkinase PF00069.25 EKX55089.1 - 3.4e-07 29.9 0.0 9.4e-07 28.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EKX55089.1 - 0.0053 16.1 0.0 0.017 14.5 0.0 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Apolipoprotein PF01442.18 EKX55089.1 - 0.31 10.9 6.6 0.73 9.7 6.6 1.5 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF3340 PF11818.8 EKX55089.1 - 5.6 7.1 10.0 8.7 6.5 4.8 2.2 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) WD40 PF00400.32 EKX55090.1 - 2.5e-08 34.4 25.4 0.016 16.1 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat TPR_2 PF07719.17 EKX55090.1 - 6.3e-05 22.8 0.5 0.099 12.8 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX55090.1 - 0.00015 21.4 0.2 2.5 8.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX55090.1 - 0.0072 16.5 0.2 2.5 8.5 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 EKX55090.1 - 0.012 15.9 0.9 1.5 9.2 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4381 PF14316.6 EKX55091.1 - 0.011 16.0 0.1 0.011 16.0 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF5367 PF17329.2 EKX55091.1 - 0.022 14.9 0.0 0.025 14.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5367) Baculo_11_kDa PF06143.11 EKX55091.1 - 0.074 12.6 0.0 0.082 12.5 0.0 1.1 1 0 0 1 1 1 0 Baculovirus 11 kDa family PspB PF06667.12 EKX55091.1 - 0.08 13.0 0.1 0.088 12.9 0.1 1.2 1 0 0 1 1 1 0 Phage shock protein B LAX PF15681.5 EKX55091.1 - 0.17 10.7 0.2 0.19 10.5 0.2 1.1 1 0 0 1 1 1 0 Lymphocyte activation family X AAA_13 PF13166.6 EKX55092.1 - 1.2 7.7 7.5 1.5 7.3 7.5 1.0 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 EKX55093.1 - 1.5e-21 76.3 21.0 2.4e-05 25.0 0.2 9.4 9 0 0 9 9 9 5 WD domain, G-beta repeat Sortase PF04203.13 EKX55093.1 - 0.001 18.8 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 Sortase domain ANAPC4_WD40 PF12894.7 EKX55093.1 - 0.0014 18.9 0.7 1.8 8.9 0.0 4.3 4 1 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX55093.1 - 0.0097 14.9 0.2 3.4 6.5 0.1 2.8 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein EF-hand_1 PF00036.32 EKX55093.1 - 0.019 14.5 0.4 0.11 12.1 0.1 2.3 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 EKX55093.1 - 0.061 13.8 0.0 0.23 12.0 0.0 2.0 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 EKX55093.1 - 0.063 13.1 0.3 0.28 11.1 0.3 2.1 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.6 EKX55093.1 - 0.063 13.2 0.9 0.64 10.1 0.1 2.9 3 0 0 3 3 3 0 EF-hand domain EF-hand_5 PF13202.6 EKX55093.1 - 0.42 10.2 1.2 0.84 9.2 0.2 2.0 2 0 0 2 2 2 0 EF hand Tma16 PF11176.8 EKX55094.1 - 3.9e-13 49.5 0.2 4.2e-13 49.4 0.2 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 Pkinase PF00069.25 EKX55096.1 - 3.3e-57 193.8 0.0 4.8e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX55096.1 - 4.1e-22 78.7 0.0 8.2e-22 77.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX55096.1 - 0.0024 17.2 0.1 0.0038 16.6 0.1 1.6 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EKX55096.1 - 0.016 14.1 0.6 0.021 13.8 0.6 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EKX55096.1 - 0.038 13.0 0.2 0.1 11.6 0.1 1.7 1 1 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 EKX55096.1 - 0.054 12.3 0.9 0.076 11.8 0.7 1.3 1 1 0 1 1 1 0 Fungal protein kinase NitrOD1 PF18549.1 EKX55096.1 - 0.063 13.3 0.1 1.5 8.8 0.0 2.5 2 0 0 2 2 2 0 Nitrosopumilus output domain 1 SKA2 PF16740.5 EKX55097.1 - 0.00016 21.4 0.9 0.00026 20.8 0.9 1.3 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 bZIP_1 PF00170.21 EKX55097.1 - 0.013 15.6 6.2 0.018 15.1 2.9 2.2 1 1 1 2 2 2 0 bZIP transcription factor Lebercilin PF15619.6 EKX55097.1 - 0.013 15.2 3.5 0.019 14.7 3.5 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease MCD_N PF17408.2 EKX55097.1 - 0.016 15.3 0.2 0.027 14.6 0.2 1.4 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain CENP-F_leu_zip PF10473.9 EKX55097.1 - 0.017 15.2 2.9 0.023 14.7 2.9 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 EKX55097.1 - 0.017 15.6 2.9 0.025 15.1 2.9 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Paralemmin PF03285.15 EKX55097.1 - 0.037 13.6 1.8 0.066 12.8 1.8 1.3 1 0 0 1 1 1 0 Paralemmin EzrA PF06160.12 EKX55097.1 - 0.039 12.1 1.8 0.053 11.7 1.8 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA TMF_TATA_bd PF12325.8 EKX55097.1 - 0.045 14.0 3.3 0.076 13.2 3.3 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding FliT PF05400.13 EKX55097.1 - 0.048 14.5 2.2 0.08 13.8 2.2 1.4 1 0 0 1 1 1 0 Flagellar protein FliT JIP_LZII PF16471.5 EKX55097.1 - 0.23 11.6 3.8 0.42 10.8 3.8 1.4 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II Cep57_MT_bd PF06657.13 EKX55097.1 - 0.24 11.9 2.9 1.6 9.2 2.9 2.2 1 1 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 EKX55097.1 - 0.29 11.2 9.9 0.11 12.6 7.4 1.6 2 0 0 2 2 1 0 Centrosome localisation domain of PPC89 TSC22 PF01166.18 EKX55097.1 - 0.66 10.3 4.3 1.3 9.4 0.5 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family M PF02370.16 EKX55097.1 - 1.8 9.4 4.0 11 7.0 0.2 2.8 1 1 1 2 2 2 0 M protein repeat Med21 PF11221.8 EKX55097.1 - 1.9 8.7 7.8 0.18 12.1 2.9 1.7 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Cupin_4 PF08007.12 EKX55098.1 - 0.00021 20.9 0.4 0.0051 16.3 0.1 2.2 2 0 0 2 2 2 2 Cupin superfamily protein Cpn10 PF00166.21 EKX55101.1 - 1.3e-19 70.0 0.3 1.5e-19 69.8 0.3 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Profilin PF00235.19 EKX55101.1 - 0.1 12.9 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Profilin NADH_oxidored PF08040.11 EKX55101.1 - 0.15 11.8 0.0 0.67 9.7 0.0 1.9 2 0 0 2 2 2 0 MNLL subunit UPF0220 PF05255.11 EKX55105.1 - 0.011 15.2 0.1 0.013 15.1 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) Pkinase PF00069.25 EKX55106.1 - 4.3e-56 190.2 0.0 4.8e-56 190.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX55106.1 - 1.7e-29 102.9 0.0 1.8e-29 102.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX55106.1 - 1.9e-05 24.1 0.4 0.0039 16.6 0.1 2.5 2 1 0 2 2 2 2 Kinase-like APH PF01636.23 EKX55106.1 - 3.3e-05 23.9 0.3 0.0019 18.2 0.3 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EKX55106.1 - 0.002 17.8 0.0 0.0052 16.4 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 EKX55106.1 - 0.055 12.5 0.1 0.091 11.8 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DLH PF01738.18 EKX55106.1 - 0.078 12.5 0.0 0.099 12.2 0.0 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family Apolipoprotein PF01442.18 EKX55109.1 - 0.00015 21.7 1.4 0.00028 20.8 1.4 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF1640 PF07798.11 EKX55109.1 - 0.0011 19.0 0.7 0.0015 18.6 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) UPF0242 PF06785.11 EKX55109.1 - 0.0032 17.6 2.1 0.0048 17.0 2.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 EKX55109.1 - 0.02 14.9 0.4 0.13 12.3 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EKX55109.1 - 0.025 14.6 1.1 0.044 13.8 1.1 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.18 EKX55109.1 - 0.044 13.1 0.3 0.066 12.5 0.3 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein BshC PF10079.9 EKX55109.1 - 0.051 12.3 2.0 0.071 11.8 2.0 1.2 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC ING PF12998.7 EKX55109.1 - 0.054 14.1 2.3 0.12 13.0 2.3 1.6 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Sec3_C_2 PF15278.6 EKX55109.1 - 0.062 13.6 1.0 3.5 8.0 1.6 2.4 2 0 0 2 2 2 0 Sec3 exocyst complex subunit AI-2E_transport PF01594.16 EKX55109.1 - 0.25 10.4 0.5 0.33 10.1 0.5 1.1 1 0 0 1 1 1 0 AI-2E family transporter TetR_C_37 PF18665.1 EKX55109.1 - 0.29 11.7 2.1 2.4 8.8 0.2 2.9 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Met_10 PF02475.16 EKX55110.1 - 0.077 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Rad51 PF08423.11 EKX55112.1 - 4.1e-105 350.6 0.0 5.9e-105 350.1 0.0 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 EKX55112.1 - 1.1e-15 57.8 0.3 1.4e-15 57.5 0.3 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 EKX55112.1 - 6.9e-07 28.8 0.0 1.2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.6 EKX55112.1 - 1.2e-05 25.0 0.0 2.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EKX55112.1 - 0.0017 18.8 0.1 0.0056 17.1 0.0 1.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EKX55112.1 - 0.0035 17.1 0.0 0.0082 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 EKX55112.1 - 0.019 14.3 0.2 0.073 12.4 0.2 1.9 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain HHH_5 PF14520.6 EKX55112.1 - 0.05 14.2 0.1 0.11 13.1 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain AurF PF11583.8 EKX55112.1 - 0.11 11.7 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 P-aminobenzoate N-oxygenase AurF F_bP_aldolase PF01116.20 EKX55113.1 - 1.6e-89 300.2 0.0 1.8e-89 299.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DUF2325 PF10087.9 EKX55113.1 - 0.088 12.9 0.1 0.45 10.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) MR_MLE_C PF13378.6 EKX55113.1 - 0.11 12.0 0.3 0.31 10.6 0.2 1.7 2 0 0 2 2 2 0 Enolase C-terminal domain-like CIA30 PF08547.12 EKX55114.1 - 1.6e-36 125.7 0.0 2e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.13 EKX55114.1 - 0.0076 16.1 0.0 0.01 15.7 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain (family 11) URO-D PF01208.17 EKX55115.1 - 2.2e-105 352.6 0.0 2.6e-105 352.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PEP-utilisers_N PF05524.13 EKX55115.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal zf-C4 PF00105.18 EKX55116.1 - 0.092 13.2 1.0 0.19 12.2 1.0 1.5 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) RNA_pol_Rpb8 PF03870.15 EKX55118.1 - 1.4e-48 164.7 1.1 1.5e-48 164.5 1.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 EKX55118.1 - 7e-07 29.3 0.5 3.6e-05 23.8 0.5 2.0 1 1 0 1 1 1 1 DNA-directed RNA polymerase, subunit G TbpB_C PF17483.2 EKX55118.1 - 0.059 13.7 0.1 0.098 13.0 0.1 1.5 1 1 0 1 1 1 0 C-lobe handle domain of Tf-binding protein B cNMP_binding PF00027.29 EKX55119.1 - 4.5e-14 52.3 0.0 8.1e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF5466 PF17554.2 EKX55119.1 - 0.047 13.9 0.2 0.14 12.4 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5466) PPR_2 PF13041.6 EKX55120.1 - 1.3e-76 252.6 0.7 2.2e-12 46.9 0.0 9.1 2 2 8 10 10 10 9 PPR repeat family PPR_3 PF13812.6 EKX55120.1 - 2.7e-68 226.0 0.0 3.7e-15 55.7 0.0 7.1 3 2 3 7 7 7 7 Pentatricopeptide repeat domain PPR PF01535.20 EKX55120.1 - 5.2e-63 205.0 13.0 1.5e-06 28.0 0.0 10.8 11 0 0 11 11 11 9 PPR repeat PPR_1 PF12854.7 EKX55120.1 - 1.3e-54 181.6 0.0 2.1e-07 30.5 0.0 10.1 10 0 0 10 10 10 9 PPR repeat PPR_long PF17177.4 EKX55120.1 - 3.5e-32 111.5 0.1 3.2e-19 69.1 0.0 4.0 1 1 2 4 4 4 3 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EKX55120.1 - 1.1e-13 50.8 16.3 2.3 9.2 0.1 8.7 6 2 3 9 9 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 EKX55120.1 - 1.2e-08 34.4 8.8 0.2 11.8 0.0 7.4 7 1 1 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX55120.1 - 1.3e-06 28.6 0.5 1.4 9.2 0.0 4.8 3 2 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EKX55120.1 - 3.5e-05 24.2 12.2 17 6.3 0.0 8.1 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_15 PF13429.6 EKX55120.1 - 7.1e-05 22.2 4.0 4 6.6 0.0 4.3 2 1 2 5 5 5 1 Tetratricopeptide repeat Clathrin PF00637.20 EKX55120.1 - 0.00036 20.4 0.0 42 4.0 0.0 5.6 2 2 2 4 4 4 0 Region in Clathrin and VPS TPR_2 PF07719.17 EKX55120.1 - 0.00083 19.3 11.4 1.7 8.9 0.0 6.9 8 0 0 8 8 8 1 Tetratricopeptide repeat BTAD PF03704.17 EKX55120.1 - 0.002 18.6 9.8 3.4 8.1 0.0 5.1 3 3 2 5 5 5 1 Bacterial transcriptional activator domain TPR_19 PF14559.6 EKX55120.1 - 0.002 18.6 10.2 2.5 8.7 0.6 5.7 5 1 1 6 6 5 1 Tetratricopeptide repeat Raf1_HTH PF18579.1 EKX55120.1 - 0.0022 17.7 0.5 0.32 10.7 0.0 4.1 4 1 1 5 5 5 1 Rubisco accumulation factor 1 helix turn helix domain TPR_16 PF13432.6 EKX55120.1 - 0.0024 18.5 11.1 0.27 11.9 0.6 5.4 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX55120.1 - 0.0026 17.5 8.1 10 6.1 0.0 6.2 8 0 0 8 8 6 0 Tetratricopeptide repeat FtsK_gamma PF09397.10 EKX55120.1 - 0.0027 17.5 0.4 32 4.4 0.0 4.9 5 0 0 5 5 5 0 Ftsk gamma domain SNAP PF14938.6 EKX55120.1 - 0.0051 16.3 3.1 0.46 9.9 0.2 3.2 2 1 2 4 4 4 2 Soluble NSF attachment protein, SNAP Glyco_trans_4_3 PF12000.8 EKX55120.1 - 0.0073 16.0 0.2 26 4.5 0.0 3.9 2 1 2 4 4 4 0 Glycosyl transferase family 4 group TPR_10 PF13374.6 EKX55120.1 - 0.0086 15.9 0.9 17 5.5 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat HRM PF02793.22 EKX55120.1 - 0.016 15.5 0.8 29 5.1 0.0 4.8 5 1 0 5 5 5 0 Hormone receptor domain TPR_12 PF13424.6 EKX55120.1 - 0.021 15.1 6.8 7.6 6.9 0.0 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.7 EKX55120.1 - 0.035 14.2 0.4 6.3 6.9 0.0 3.9 2 2 3 5 5 5 0 Domain of Unknown Function (DUF3856) MRP-S27 PF10037.9 EKX55120.1 - 0.057 12.3 0.0 5.3 5.8 0.0 2.5 2 1 2 4 4 4 0 Mitochondrial 28S ribosomal protein S27 Ank_2 PF12796.7 EKX55123.1 - 3.7e-26 91.5 4.1 5.4e-09 36.5 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX55123.1 - 7.1e-24 83.9 3.8 2.4e-09 37.5 0.4 3.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX55123.1 - 1.4e-23 82.3 7.5 0.00014 22.2 0.1 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 EKX55123.1 - 5e-21 74.5 6.2 9.4e-06 25.8 0.1 5.1 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX55123.1 - 3e-18 64.0 4.7 0.0008 19.7 0.0 6.1 6 1 0 6 6 6 3 Ankyrin repeat IN_DBD_C PF00552.21 EKX55124.1 - 0.11 11.9 0.1 0.29 10.5 0.1 1.8 1 1 0 1 1 1 0 Integrase DNA binding domain Malic_M PF03949.15 EKX55125.1 - 6.7e-98 327.1 0.0 9.2e-98 326.6 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EKX55125.1 - 8.4e-70 234.3 0.0 1.3e-69 233.7 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain TAFII28 PF04719.14 EKX55125.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 hTAFII28-like protein conserved region DUF4471 PF14740.6 EKX55126.1 - 9.6e-84 281.2 4.8 9.6e-84 281.2 4.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4471) DUF4470 PF14737.6 EKX55126.1 - 1.7e-17 63.4 0.0 3.3e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) YL1_C PF08265.11 EKX55126.1 - 1.6e-16 59.8 0.0 2.7e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain RNA_polI_A34 PF08208.11 EKX55126.1 - 0.019 15.1 1.0 0.028 14.5 0.2 1.6 1 1 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 zf-HIT PF04438.16 EKX55126.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 HIT zinc finger MORN PF02493.20 EKX55127.1 - 0.00023 20.9 9.4 0.23 11.5 0.0 4.8 5 0 0 5 5 5 3 MORN repeat ubiquitin PF00240.23 EKX55128.1 - 8.9e-13 47.8 0.0 3.7e-07 29.8 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 EKX55128.1 - 5.3e-05 23.0 0.0 0.041 13.7 0.0 2.8 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EKX55128.1 - 0.067 13.3 0.0 0.62 10.2 0.0 2.3 2 1 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Peptidase_S49_N PF08496.10 EKX55129.1 - 0.0054 16.8 6.3 0.0074 16.4 6.3 1.2 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Presenilin PF01080.17 EKX55129.1 - 0.045 12.5 6.6 0.048 12.4 6.6 1.1 1 0 0 1 1 1 0 Presenilin Caldesmon PF02029.15 EKX55129.1 - 0.064 12.0 27.4 0.085 11.6 27.4 1.1 1 0 0 1 1 1 0 Caldesmon Amidase PF01425.21 EKX55129.1 - 0.092 11.7 1.3 0.097 11.6 1.3 1.1 1 0 0 1 1 1 0 Amidase MCM_bind PF09739.9 EKX55129.1 - 0.1 11.0 4.0 0.12 10.8 4.0 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF4776 PF16003.5 EKX55129.1 - 0.13 11.2 8.1 0.15 11.0 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) RR_TM4-6 PF06459.12 EKX55129.1 - 0.15 11.9 11.3 0.19 11.5 11.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 D5_N PF08706.11 EKX55129.1 - 0.15 12.3 5.1 0.23 11.7 5.1 1.4 1 0 0 1 1 1 0 D5 N terminal like Raftlin PF15250.6 EKX55129.1 - 0.18 10.5 4.5 0.2 10.4 4.5 1.1 1 0 0 1 1 1 0 Raftlin CDC45 PF02724.14 EKX55129.1 - 0.3 9.3 13.2 0.42 8.8 13.2 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2828 PF11443.8 EKX55129.1 - 0.4 8.7 8.4 0.49 8.4 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DDHD PF02862.17 EKX55129.1 - 0.41 10.8 3.0 0.47 10.6 3.0 1.1 1 0 0 1 1 1 0 DDHD domain Hid1 PF12722.7 EKX55129.1 - 0.45 8.6 7.1 0.49 8.5 7.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NARP1 PF12569.8 EKX55129.1 - 0.46 9.3 13.9 0.6 9.0 13.9 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AAA_11 PF13086.6 EKX55129.1 - 0.47 10.2 9.3 0.58 9.9 9.3 1.2 1 0 0 1 1 1 0 AAA domain G6B PF15096.6 EKX55129.1 - 0.51 10.1 2.5 0.64 9.8 2.5 1.2 1 0 0 1 1 1 0 G6B family DUF1682 PF07946.14 EKX55129.1 - 0.78 8.9 28.7 1 8.5 28.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF2151 PF10221.9 EKX55129.1 - 0.88 8.1 7.5 1 7.9 7.5 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator eIF3_subunit PF08597.10 EKX55129.1 - 0.97 9.3 21.7 1.2 9.0 21.7 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit NPR3 PF03666.13 EKX55129.1 - 1 8.1 8.1 1.2 7.8 8.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 U79_P34 PF03064.16 EKX55129.1 - 1.3 8.3 16.9 1.6 8.0 16.9 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Sec62 PF03839.16 EKX55129.1 - 3.2 7.2 8.8 4.2 6.8 8.8 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 ALMT PF11744.8 EKX55129.1 - 4.7 5.9 6.9 5.3 5.8 6.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Merozoite_SPAM PF07133.11 EKX55129.1 - 5.2 7.0 21.1 2.7 8.0 19.0 1.5 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) XRN_M PF17846.1 EKX55129.1 - 5.5 5.8 12.6 7.3 5.4 12.6 1.1 1 0 0 1 1 1 0 Xrn1 helical domain MAJIN PF15077.6 EKX55129.1 - 8.4 6.1 9.2 11 5.7 9.2 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF4746 PF15928.5 EKX55129.1 - 10 5.5 14.5 13 5.1 14.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) EzrA PF06160.12 EKX55130.1 - 2.1e-05 23.0 23.0 0.00052 18.3 0.1 7.1 3 2 4 7 7 7 4 Septation ring formation regulator, EzrA HsbA PF12296.8 EKX55130.1 - 0.032 14.6 0.3 0.032 14.6 0.3 5.3 4 1 3 7 7 7 0 Hydrophobic surface binding protein A ATG16 PF08614.11 EKX55130.1 - 0.48 10.6 167.9 0.16 12.1 2.3 9.3 4 3 4 8 8 8 0 Autophagy protein 16 (ATG16) GAS PF13851.6 EKX55130.1 - 0.54 9.6 140.5 0.028 13.8 17.0 9.2 3 2 6 9 9 9 0 Growth-arrest specific micro-tubule binding MutS_V PF00488.21 EKX55131.1 - 2.4e-24 86.4 0.0 5.9e-24 85.1 0.0 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EKX55131.1 - 6.7e-05 23.2 5.2 9.4e-05 22.7 1.2 2.6 2 2 0 2 2 2 1 MutS domain III AAA_21 PF13304.6 EKX55131.1 - 0.00017 21.5 0.3 0.016 15.0 0.1 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EKX55131.1 - 0.068 13.4 3.3 0.26 11.5 0.2 3.0 3 1 0 3 3 3 0 AAA domain AAA_16 PF13191.6 EKX55131.1 - 1.1 9.6 7.7 1.1 9.7 2.1 3.3 1 1 0 2 2 2 0 AAA ATPase domain 2-Hacid_dh_C PF02826.19 EKX55132.1 - 3.6e-51 173.0 0.0 5.2e-51 172.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EKX55132.1 - 7.1e-25 87.2 0.0 8.7e-25 86.9 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EKX55132.1 - 0.0026 18.0 0.0 0.017 15.3 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 EKX55132.1 - 0.15 11.3 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HrpB1_HrpK PF09613.10 EKX55134.1 - 0.0027 17.3 0.0 0.0049 16.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB1_HrpK) BRCT PF00533.26 EKX55134.1 - 0.041 14.3 0.1 3 8.3 0.0 2.4 1 1 1 2 2 2 0 BRCA1 C Terminus (BRCT) domain PFEMP PF03011.15 EKX55134.1 - 0.11 13.1 5.5 0.22 12.2 5.5 1.4 1 0 0 1 1 1 0 PFEMP DBL domain H_PPase PF03030.16 EKX55137.1 - 0.035 12.8 0.2 0.046 12.4 0.2 1.1 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase Biotin_lipoyl PF00364.22 EKX55138.1 - 1.9e-11 43.6 1.5 2.7e-11 43.1 1.5 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EKX55138.1 - 0.0091 15.8 1.0 0.41 10.5 0.3 2.3 1 1 1 2 2 2 2 Biotin-lipoyl like AIM24 PF01987.17 EKX55138.1 - 0.011 15.6 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial biogenesis AIM24 PP2C PF00481.21 EKX55139.1 - 2.2e-09 37.3 0.0 1.1e-07 31.8 0.0 2.4 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EKX55139.1 - 2.6e-05 24.0 0.0 0.00011 21.9 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C Herpes_DNAp_acc PF04929.12 EKX55139.1 - 3.9 6.3 4.8 6 5.7 4.8 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Ion_trans PF00520.31 EKX55140.1 - 3e-32 111.8 17.3 5.2e-32 111.0 17.3 1.4 1 0 0 1 1 1 1 Ion transport protein EF-hand_1 PF00036.32 EKX55140.1 - 2.3e-08 33.0 0.2 0.00032 20.0 0.0 3.6 3 0 0 3 3 3 2 EF hand PKD_channel PF08016.12 EKX55140.1 - 3.5e-08 32.5 3.4 3.5e-08 32.5 3.4 2.4 1 1 1 2 2 2 2 Polycystin cation channel EF-hand_7 PF13499.6 EKX55140.1 - 4.8e-08 33.3 4.9 0.00011 22.6 1.5 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EKX55140.1 - 1e-06 28.2 2.1 0.00031 20.5 0.0 3.8 4 0 0 4 4 4 1 EF-hand domain EF-hand_5 PF13202.6 EKX55140.1 - 0.0077 15.7 0.7 0.098 12.2 0.0 3.0 3 0 0 3 3 3 1 EF hand CheF-arch PF04283.12 EKX55140.1 - 0.019 14.7 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Chemotaxis signal transduction system protein F from archaea DUF1690 PF07956.11 EKX55140.1 - 1.3 9.5 3.7 8.8 6.8 3.7 2.2 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) Glyco_transf_41 PF13844.6 EKX55141.1 - 1.2e-34 119.6 0.0 1.2e-30 106.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_12 PF13424.6 EKX55141.1 - 7.8e-11 42.1 14.3 2.7e-05 24.4 0.2 5.5 2 2 6 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 EKX55141.1 - 1.7e-09 37.1 21.0 0.071 13.3 0.7 7.8 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 EKX55141.1 - 6e-09 36.3 9.7 0.0017 18.9 0.1 4.4 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EKX55141.1 - 5e-08 32.4 13.0 0.013 15.3 0.1 6.6 7 1 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX55141.1 - 1.5e-06 28.4 2.8 0.031 14.5 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EKX55141.1 - 2.3e-06 27.4 9.3 2.2 8.7 0.1 7.4 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX55141.1 - 9.5e-06 26.0 18.2 0.023 15.5 0.3 7.2 3 2 4 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX55141.1 - 0.0002 21.0 4.2 0.48 10.2 0.0 5.3 5 1 1 6 6 6 1 TPR repeat TPR_10 PF13374.6 EKX55141.1 - 0.00034 20.4 0.1 0.00034 20.4 0.1 6.2 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX55141.1 - 0.00039 20.6 0.0 8.4 7.0 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX55141.1 - 0.0013 19.4 0.1 0.0013 19.4 0.1 5.5 5 2 2 7 7 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 EKX55141.1 - 0.014 14.7 1.1 0.042 13.1 1.0 1.9 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_21 PF09976.9 EKX55141.1 - 0.014 15.1 4.7 0.11 12.2 2.8 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 EKX55141.1 - 0.068 12.5 6.3 0.25 10.7 3.8 2.5 2 1 0 2 2 2 0 MalT-like TPR region HrpB1_HrpK PF09613.10 EKX55141.1 - 0.074 12.7 0.1 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) BsuBI_PstI_RE_N PF17728.1 EKX55141.1 - 0.1 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease HTH domain TPR_4 PF07721.14 EKX55141.1 - 0.12 13.0 0.1 0.12 13.0 0.1 5.0 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EKX55141.1 - 0.39 10.9 7.7 33 4.8 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat SAP PF02037.27 EKX55142.1 - 1.3e-06 28.0 0.5 3e-06 26.8 0.5 1.7 1 0 0 1 1 1 1 SAP domain DUF45 PF01863.17 EKX55143.1 - 0.1 12.6 0.0 0.26 11.3 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function DUF45 B56 PF01603.20 EKX55145.1 - 0.12 11.4 0.1 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) WD40 PF00400.32 EKX55146.1 - 2.1e-10 41.0 9.7 0.073 14.0 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat tRNA_m1G_MT PF01746.21 EKX55147.1 - 3.6e-18 66.0 0.0 3.2e-14 53.1 0.0 2.4 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase F5_F8_type_C PF00754.25 EKX55148.1 - 0.012 15.8 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 0 F5/8 type C domain F5_F8_type_C PF00754.25 EKX55149.1 - 0.00043 20.4 0.0 0.00051 20.2 0.0 1.1 1 0 0 1 1 1 1 F5/8 type C domain Sad1_UNC PF07738.13 EKX55149.1 - 0.0012 18.9 0.0 0.0014 18.7 0.0 1.0 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.25 EKX55150.1 - 9.7e-06 25.7 0.0 1.2e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 F5/8 type C domain TIG PF01833.24 EKX55156.1 - 0.089 12.9 13.6 1.1 9.4 0.3 3.5 2 1 1 3 3 3 0 IPT/TIG domain SAM_1 PF00536.30 EKX55157.1 - 0.0044 17.4 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Skp1 PF01466.19 EKX55157.1 - 0.028 14.5 0.2 3.6 7.8 0.0 3.2 3 0 0 3 3 3 0 Skp1 family, dimerisation domain TMEM154 PF15102.6 EKX55157.1 - 0.13 12.2 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF4199 PF13858.6 EKX55157.1 - 0.21 12.0 6.3 0.17 12.3 1.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) Cytochrom_C_asm PF01578.20 EKX55157.1 - 0.44 10.3 6.2 0.11 12.3 3.1 1.5 2 0 0 2 2 2 0 Cytochrome C assembly protein DUF2207 PF09972.9 EKX55157.1 - 1.6 7.4 5.2 17 4.0 4.3 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF1515 PF07439.11 EKX55158.1 - 0.00094 19.2 7.8 0.00097 19.2 5.6 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1515) Filament PF00038.21 EKX55158.1 - 0.0038 16.9 22.6 0.0058 16.3 22.6 1.2 1 0 0 1 1 1 1 Intermediate filament protein L27_2 PF09045.10 EKX55158.1 - 0.058 13.4 5.5 0.46 10.5 3.4 2.8 1 1 1 2 2 2 0 L27_2 AKNA PF12443.8 EKX55158.1 - 0.074 13.7 10.9 0.59 10.8 6.5 2.5 1 1 1 2 2 2 0 AT-hook-containing transcription factor HSBP1 PF06825.12 EKX55158.1 - 0.11 12.4 10.6 0.12 12.2 0.8 3.4 3 0 0 3 3 3 0 Heat shock factor binding protein 1 FlaC_arch PF05377.11 EKX55158.1 - 0.13 12.7 1.2 0.13 12.7 1.2 3.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) ADIP PF11559.8 EKX55158.1 - 0.16 12.0 30.1 0.024 14.7 22.4 2.6 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Syntaxin-6_N PF09177.11 EKX55158.1 - 0.18 12.4 14.0 0.06 13.9 10.4 2.1 2 1 0 2 2 2 0 Syntaxin 6, N-terminal MitMem_reg PF13012.6 EKX55158.1 - 0.19 12.1 8.1 1.3 9.4 7.6 2.5 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function FliE PF02049.18 EKX55158.1 - 0.34 11.1 13.5 1.6 8.9 0.2 3.3 1 1 2 3 3 3 0 Flagellar hook-basal body complex protein FliE AATF-Che1 PF13339.6 EKX55158.1 - 0.42 11.3 13.3 0.41 11.3 12.3 1.4 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor IucA_IucC PF04183.12 EKX55158.1 - 0.55 9.8 3.6 0.79 9.2 3.5 1.4 1 1 0 1 1 1 0 IucA / IucC family GrpE PF01025.19 EKX55158.1 - 0.62 9.7 24.8 0.45 10.2 4.2 3.0 1 1 3 4 4 4 0 GrpE PspA_IM30 PF04012.12 EKX55158.1 - 0.69 9.4 27.1 2.2 7.8 26.8 2.0 1 1 0 1 1 1 0 PspA/IM30 family FAM76 PF16046.5 EKX55158.1 - 0.87 8.9 21.6 2.1 7.6 21.6 1.6 1 1 0 1 1 1 0 FAM76 protein DUF3584 PF12128.8 EKX55158.1 - 0.96 6.9 24.9 1.2 6.6 24.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 EKX55158.1 - 1.2 9.2 8.7 6.3 6.8 4.2 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.19 EKX55158.1 - 1.7 6.5 12.9 2.1 6.1 12.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4618 PF15397.6 EKX55158.1 - 1.8 7.9 23.3 0.079 12.4 11.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) HIP1_clath_bdg PF16515.5 EKX55158.1 - 2.5 8.7 26.8 0.31 11.7 9.9 2.5 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CREPT PF16566.5 EKX55158.1 - 2.9 8.1 17.9 1.1 9.5 11.4 2.3 1 1 2 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour CorA PF01544.18 EKX55158.1 - 3.2 7.0 17.1 0.8 9.0 8.3 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Prominin PF05478.11 EKX55158.1 - 3.9 5.3 14.1 5.4 4.8 14.1 1.1 1 0 0 1 1 1 0 Prominin DUF4407 PF14362.6 EKX55158.1 - 4.3 6.6 20.1 8.2 5.7 20.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 EKX55158.1 - 4.4 7.5 19.3 3 8.0 14.6 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ALMT PF11744.8 EKX55158.1 - 5.6 5.7 10.9 7.3 5.3 10.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter YtxH PF12732.7 EKX55158.1 - 5.8 7.5 14.7 5.1e+03 -1.9 14.3 3.6 1 1 1 2 2 2 0 YtxH-like protein zf-HC5HC2H_2 PF13832.6 EKX55160.1 - 4.3e-30 104.1 3.5 4.3e-30 104.1 3.5 2.8 2 1 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EKX55160.1 - 2e-21 76.1 2.4 2e-21 76.1 2.4 3.1 2 1 1 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 EKX55160.1 - 2.6e-11 42.9 9.0 2.6e-11 42.9 9.0 3.9 6 0 0 6 6 6 2 PHD-finger PHD PF00628.29 EKX55160.1 - 1.1e-09 38.1 32.9 2.4e-08 33.7 11.8 3.1 3 1 0 3 3 3 2 PHD-finger zf-RING-like PF08746.11 EKX55160.1 - 0.015 15.6 9.0 0.015 15.6 9.0 3.1 3 1 1 4 4 4 0 RING-like domain zf-PHD-like PF15446.6 EKX55160.1 - 0.56 9.8 20.6 0.12 12.0 9.8 2.9 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 EKX55160.1 - 4.5 7.2 33.9 0.14 12.1 2.8 3.7 3 2 1 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H_2 PF13832.6 EKX55161.1 - 9e-27 93.4 6.5 9e-27 93.4 6.5 2.2 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EKX55161.1 - 2.9e-19 69.1 5.1 2.9e-19 69.1 5.1 3.1 2 1 1 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 EKX55161.1 - 6.9e-07 28.7 5.0 6.9e-07 28.7 5.0 3.9 4 0 0 4 4 4 1 PHD-finger PHD PF00628.29 EKX55161.1 - 1.4e-05 24.9 37.7 1.7e-05 24.6 12.9 3.3 3 1 0 3 3 3 2 PHD-finger C1_1 PF00130.22 EKX55161.1 - 0.0037 17.1 4.0 0.0037 17.1 4.0 4.2 2 2 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 EKX55161.1 - 0.033 14.5 26.3 0.033 14.5 2.6 4.2 3 1 2 5 5 5 0 C1 domain DUF2396 PF09654.10 EKX55161.1 - 0.12 12.5 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2396) zf-PHD-like PF15446.6 EKX55161.1 - 3.4 7.3 23.7 0.064 12.9 6.1 2.5 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain LMBR1 PF04791.16 EKX55162.1 - 0.32 9.8 3.3 0.44 9.4 3.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein PepSY_TM_like_2 PF16357.5 EKX55162.1 - 4 7.4 5.1 8.4 6.3 0.1 2.4 2 1 0 2 2 2 0 Putative PepSY_TM-like CbiX PF01903.17 EKX55163.1 - 1.7e-08 34.8 0.0 7.7e-05 23.0 0.0 3.2 3 0 0 3 3 3 2 CbiX E2F_TDP PF02319.20 EKX55163.1 - 0.033 14.2 0.8 0.12 12.5 0.1 2.4 2 0 0 2 2 2 0 E2F/DP family winged-helix DNA-binding domain FlpD PF02662.16 EKX55163.1 - 0.27 11.2 2.2 0.48 10.4 1.5 1.8 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit NPL4 PF05021.15 EKX55164.1 - 6.7e-18 65.1 0.2 3.8e-10 39.6 0.1 3.2 1 1 1 2 2 2 2 NPL4 family CS PF04969.16 EKX55165.1 - 1.7e-08 35.3 0.0 2.4e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 CS domain RAP1 PF07218.11 EKX55166.1 - 0.14 10.4 2.4 0.12 10.7 2.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SWIM PF04434.17 EKX55166.1 - 0.22 11.2 2.9 0.38 10.5 2.9 1.4 1 0 0 1 1 1 0 SWIM zinc finger DUF3446 PF11928.8 EKX55166.1 - 0.24 11.7 9.6 0.15 12.4 7.2 1.8 2 0 0 2 2 2 0 Early growth response N-terminal domain SR-25 PF10500.9 EKX55166.1 - 0.32 10.6 12.8 0.52 9.9 11.9 1.7 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1117 PF06547.12 EKX55166.1 - 0.9 10.1 7.9 1.1 9.8 1.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1117) IMUP PF15761.5 EKX55166.1 - 5.3 7.8 12.3 5.5 7.7 11.2 1.6 1 1 0 1 1 1 0 Immortalisation up-regulated protein PKD_channel PF08016.12 EKX55167.1 - 4.8e-24 84.8 0.3 9e-24 83.9 0.3 1.3 1 0 0 1 1 1 1 Polycystin cation channel Mpv17_PMP22 PF04117.12 EKX55168.1 - 1.6e-10 41.0 0.6 3.3e-10 40.0 0.6 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family Cyt-b5 PF00173.28 EKX55169.1 - 4.3e-10 39.6 0.0 7.2e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain WD40 PF00400.32 EKX55171.1 - 1e-15 57.8 7.5 0.0017 19.2 0.4 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX55171.1 - 7.1e-07 29.4 0.3 1.3 9.3 0.0 4.6 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 EKX55171.1 - 0.15 10.4 0.0 2.9 6.1 0.0 2.4 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Acetyltransf_1 PF00583.25 EKX55172.1 - 3.3e-11 43.5 0.3 4.6e-11 43.0 0.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EKX55172.1 - 2.2e-06 28.0 0.2 5e-06 26.9 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EKX55172.1 - 3.7e-06 26.9 0.0 6.1e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EKX55172.1 - 4.9e-05 23.2 0.0 8.6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EKX55172.1 - 0.0029 17.7 0.0 0.0039 17.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 EKX55172.1 - 0.0044 16.8 0.0 0.0059 16.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_3 PF13302.7 EKX55172.1 - 0.023 15.3 0.0 0.035 14.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain OTCace_N PF02729.21 EKX55173.1 - 0.0059 16.6 0.0 0.0081 16.2 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Jiraiya PF15038.6 EKX55174.1 - 0.01 15.2 4.2 0.016 14.6 4.2 1.3 1 0 0 1 1 1 0 Jiraiya BTP PF05232.12 EKX55174.1 - 0.37 10.9 6.0 0.87 9.7 6.0 1.7 1 0 0 1 1 1 0 Chlorhexidine efflux transporter CCDC71L PF15374.6 EKX55175.1 - 0.27 10.5 17.0 0.34 10.1 17.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L DUF2828 PF11443.8 EKX55175.1 - 0.89 7.6 10.0 1 7.3 10.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DDHD PF02862.17 EKX55175.1 - 1.8 8.7 4.6 2.3 8.3 4.6 1.3 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.12 EKX55175.1 - 1.9 8.3 17.7 2.6 7.8 17.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF5401 PF17380.2 EKX55175.1 - 2.3 6.2 36.3 1.4 6.9 33.6 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5401) Presenilin PF01080.17 EKX55175.1 - 3.5 6.3 11.9 4.7 5.9 11.9 1.1 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 EKX55175.1 - 4.3 6.0 6.6 4.9 5.9 6.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Hid1 PF12722.7 EKX55175.1 - 5.3 5.0 8.1 6.5 4.7 8.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein IBR PF01485.21 EKX55177.1 - 0.0024 18.1 27.7 0.003 17.8 6.7 3.6 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain Mem_trans PF03547.18 EKX55177.1 - 0.021 13.2 0.4 0.025 13.0 0.4 1.2 1 0 0 1 1 1 0 Membrane transport protein zf-H2C2_2 PF13465.6 EKX55177.1 - 0.1 13.0 0.1 0.1 13.0 0.1 5.0 6 0 0 6 6 6 0 Zinc-finger double domain Nop14 PF04147.12 EKX55177.1 - 1.2 7.3 43.6 1.7 6.7 43.6 1.2 1 0 0 1 1 1 0 Nop14-like family CCSAP PF15748.5 EKX55177.1 - 2.6 8.2 16.8 4.2 7.5 16.8 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated SpoIIP PF07454.11 EKX55177.1 - 3.7 6.9 16.3 6.7 6.1 16.3 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DNA_pol_phi PF04931.13 EKX55177.1 - 7.6 4.5 54.3 15 3.5 54.3 1.5 1 0 0 1 1 1 0 DNA polymerase phi RAMA PF18755.1 EKX55178.1 - 0.00034 21.0 0.0 0.00082 19.8 0.0 1.7 1 0 0 1 1 1 1 Restriction Enzyme Adenine Methylase Associated Tudor-knot PF11717.8 EKX55178.1 - 0.0017 18.2 0.1 0.0046 16.8 0.1 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain MBT PF02820.18 EKX55178.1 - 0.0072 16.6 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 mbt repeat DEC-1_N PF04625.13 EKX55178.1 - 0.034 13.2 6.0 0.059 12.4 6.0 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Aldo_ket_red PF00248.21 EKX55181.1 - 1.1e-31 110.1 0.0 9e-29 100.6 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Aquarius_N PF16399.5 EKX55181.1 - 0.12 10.4 0.1 0.17 9.9 0.1 1.1 1 0 0 1 1 1 0 Intron-binding protein aquarius N-terminus RPE65 PF03055.15 EKX55182.1 - 1.4e-54 186.0 0.0 1.8e-54 185.7 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein RMF PF04957.12 EKX55182.1 - 0.06 13.6 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 Ribosome modulation factor DUF481 PF04338.12 EKX55183.1 - 0.23 11.5 0.0 3.9 7.4 0.0 2.3 1 1 0 1 1 1 0 Protein of unknown function, DUF481 TFIIA PF03153.13 EKX55184.1 - 1.9e-06 28.1 21.8 2.4e-06 27.8 21.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 EKX55184.1 - 0.59 10.5 10.5 0.043 14.2 2.1 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DNA_pol_phi PF04931.13 EKX55184.1 - 0.9 7.6 38.3 1.5 6.9 38.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi PPP4R2 PF09184.11 EKX55184.1 - 1.6 8.3 26.1 0.036 13.7 14.7 2.2 2 0 0 2 2 2 0 PPP4R2 CobT PF06213.12 EKX55184.1 - 4.4 6.6 34.4 0.43 9.9 17.4 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DUF641 PF04859.12 EKX55184.1 - 5.6 7.3 9.3 10 6.5 7.8 2.4 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) FixQ PF05545.11 EKX55185.1 - 0.041 13.9 2.4 5 7.2 0.0 2.9 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ HupE_UreJ_2 PF13795.6 EKX55185.1 - 0.13 11.9 4.5 0.18 11.5 1.7 2.2 2 0 0 2 2 2 0 HupE / UreJ protein SnoaL_3 PF13474.6 EKX55187.1 - 2.5e-22 79.4 0.0 5.3e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EKX55187.1 - 4.5e-08 33.5 0.0 1.8e-07 31.5 0.0 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 EKX55187.1 - 0.00031 21.3 0.0 0.00081 20.0 0.0 1.7 1 0 0 1 1 1 1 SnoaL-like domain UVR PF02151.19 EKX55187.1 - 0.00049 19.7 0.1 0.001 18.7 0.1 1.6 1 0 0 1 1 1 1 UvrB/uvrC motif SnoaL_4 PF13577.6 EKX55187.1 - 0.00051 20.2 0.1 0.0029 17.7 0.0 2.3 2 1 0 2 2 2 1 SnoaL-like domain CaMKII_AD PF08332.10 EKX55187.1 - 0.001 19.2 0.1 0.0018 18.4 0.1 1.4 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain PolyA_pol_arg_C PF12626.7 EKX55188.1 - 0.0077 16.3 0.1 0.014 15.4 0.1 1.4 1 0 0 1 1 1 1 Polymerase A arginine-rich C-terminus DEAD PF00270.29 EKX55190.1 - 1.1e-35 122.9 0.1 2.1e-35 122.1 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX55190.1 - 1.2e-19 70.6 1.0 2.5e-17 63.2 0.1 3.5 3 1 1 4 4 4 2 Helicase conserved C-terminal domain ResIII PF04851.15 EKX55190.1 - 0.00012 22.2 0.0 0.00028 20.9 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EKX55190.1 - 0.0036 16.1 0.0 0.0057 15.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.6 EKX55190.1 - 0.065 13.5 0.5 0.62 10.3 0.4 2.4 1 1 0 1 1 1 0 AAA domain DZR PF12773.7 EKX55191.1 - 0.18 11.9 1.0 4.2 7.5 0.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon RRM_1 PF00076.22 EKX55192.1 - 5.5e-18 64.5 0.0 8.3e-08 31.9 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EKX55192.1 - 0.0033 17.5 0.1 0.16 12.0 0.0 2.4 2 0 0 2 2 2 1 RNA binding motif DUF3487 PF11990.8 EKX55192.1 - 0.54 10.2 3.0 1.2 9.1 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) DNA_pol_A_exo1 PF01612.20 EKX55193.1 - 7.6e-18 64.8 0.0 1.4e-17 64.0 0.0 1.3 1 1 0 1 1 1 1 3'-5' exonuclease KH_1 PF00013.29 EKX55193.1 - 9.8e-05 22.1 0.0 0.00022 21.0 0.0 1.7 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 EKX55193.1 - 0.0073 16.2 0.0 0.023 14.6 0.0 1.8 2 0 0 2 2 2 1 KH domain Com_YlbF PF06133.11 EKX55194.1 - 0.88 10.2 7.6 1.7 9.3 4.1 2.9 2 1 2 4 4 4 0 Control of competence regulator ComK, YlbF/YmcA EF-hand_7 PF13499.6 EKX55194.1 - 9.1 6.8 8.7 3.7 8.1 0.2 3.3 2 2 0 2 2 2 0 EF-hand domain pair Syntaxin PF00804.25 EKX55195.1 - 4e-47 160.5 14.3 4e-47 160.5 14.3 1.9 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 EKX55195.1 - 5.6e-10 39.1 1.1 5.6e-10 39.1 1.1 2.2 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.6 EKX55195.1 - 2e-06 28.1 4.3 2e-06 28.1 4.3 3.6 3 1 1 4 4 4 1 Syntaxin-like protein GN3L_Grn1 PF08701.11 EKX55195.1 - 0.74 10.0 6.0 4.3 7.5 0.1 3.5 3 0 0 3 3 3 0 GNL3L/Grn1 putative GTPase DUF848 PF05852.11 EKX55195.1 - 0.76 9.9 11.4 1.6 8.8 0.6 2.4 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF2203 PF09969.9 EKX55195.1 - 2.2 9.0 12.4 1.4 9.7 0.6 3.2 2 2 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF745 PF05335.13 EKX55195.1 - 3.1 7.5 18.7 0.22 11.3 6.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Trs65 PF12735.7 EKX55196.1 - 0.034 13.6 0.0 0.14 11.5 0.0 1.9 1 1 0 2 2 2 0 TRAPP trafficking subunit Trs65 ASXH PF13919.6 EKX55196.1 - 0.067 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Asx homology domain Cellulase PF00150.18 EKX55197.1 - 1.4e-32 113.3 0.0 2.7e-32 112.3 0.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 EKX55197.1 - 6.3e-12 45.9 0.0 1.1e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_1 PF00232.18 EKX55197.1 - 0.00067 18.2 0.0 0.0024 16.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 1 Glyco_hydro_42 PF02449.15 EKX55197.1 - 0.01 15.2 0.0 0.16 11.2 0.0 2.2 2 0 0 2 2 2 0 Beta-galactosidase DUF5540 PF17694.1 EKX55199.1 - 0.014 15.9 0.7 0.42 11.2 0.0 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5540) DUF1853 PF08907.11 EKX55199.1 - 0.095 12.4 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1853) PDZ_2 PF13180.6 EKX55200.1 - 1.7e-05 25.0 0.0 3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX55200.1 - 0.00031 20.7 0.0 0.00079 19.3 0.0 1.8 1 1 0 1 1 1 1 Tricorn protease PDZ domain PDZ_6 PF17820.1 EKX55200.1 - 0.00063 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX55200.1 - 0.012 15.9 0.0 0.03 14.7 0.0 1.6 2 0 0 2 2 2 0 PDZ domain LapA_dom PF06305.11 EKX55200.1 - 0.073 12.9 0.5 0.073 12.9 0.5 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain G3P_acyltransf PF02660.15 EKX55200.1 - 0.085 12.9 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase SfLAP PF11139.8 EKX55200.1 - 0.099 12.1 0.9 2.1 7.8 0.1 2.0 1 1 0 2 2 2 0 Sap, sulfolipid-1-addressing protein PCI PF01399.27 EKX55201.1 - 8.3e-11 42.3 2.1 1.9e-10 41.2 0.8 2.2 1 1 1 2 2 2 1 PCI domain TPR_1 PF00515.28 EKX55201.1 - 0.14 12.0 3.4 0.2 11.5 1.7 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4375 PF14300.6 EKX55202.1 - 0.71 10.1 7.4 0.32 11.3 0.5 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4375) EF-hand_1 PF00036.32 EKX55203.1 - 1.7e-13 49.1 3.8 1.6e-05 24.1 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EKX55203.1 - 1.4e-12 46.4 1.2 3.6e-06 26.5 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EKX55203.1 - 2e-12 47.4 0.4 2.7e-12 47.0 0.0 1.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 EKX55203.1 - 3.6e-08 33.1 3.1 2.4e-05 24.1 0.1 2.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EKX55203.1 - 1e-07 31.1 2.8 7.4e-05 22.1 0.1 3.0 2 1 1 3 3 3 2 EF hand EF-hand_9 PF14658.6 EKX55203.1 - 0.00012 22.3 0.0 0.00018 21.8 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_14 PF17959.1 EKX55203.1 - 0.0067 16.8 0.0 0.41 11.0 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain DUF5580 PF17743.1 EKX55203.1 - 0.2 10.2 0.0 0.23 10.0 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) RWP-RK PF02042.15 EKX55205.1 - 5.3e-14 51.9 0.0 7.9e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 RWP-RK domain HTH_8 PF02954.19 EKX55205.1 - 0.005 16.6 0.3 0.13 12.0 0.0 2.3 1 1 1 2 2 2 1 Bacterial regulatory protein, Fis family Sigma70_r4_2 PF08281.12 EKX55205.1 - 0.015 15.0 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 AAA_2 PF07724.14 EKX55206.1 - 2.1e-58 197.2 0.0 2.2e-54 184.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EKX55206.1 - 1.1e-34 118.5 1.0 1.1e-34 118.5 1.0 3.1 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EKX55206.1 - 2e-26 91.8 1.7 5.2e-26 90.5 0.1 2.7 3 0 0 3 3 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EKX55206.1 - 9.9e-26 90.7 0.0 1.4e-12 48.2 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EKX55206.1 - 3.8e-18 65.8 0.0 9.8e-13 48.3 0.0 3.1 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EKX55206.1 - 2e-12 47.1 0.1 8.1e-08 32.1 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain Clp_N PF02861.20 EKX55206.1 - 2.2e-08 34.1 0.2 1.9e-06 27.9 0.1 3.2 2 0 0 2 2 2 1 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 EKX55206.1 - 2.3e-08 34.6 12.5 4.9e-05 23.8 0.1 5.4 4 2 2 7 7 6 2 AAA ATPase domain AAA_22 PF13401.6 EKX55206.1 - 7.3e-08 32.8 2.8 0.05 13.9 0.1 5.0 3 2 1 4 4 3 2 AAA domain AAA_14 PF13173.6 EKX55206.1 - 2.2e-07 31.0 0.0 0.0043 17.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EKX55206.1 - 6.2e-07 29.1 0.0 0.0011 18.5 0.0 3.0 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 EKX55206.1 - 1.4e-06 28.2 0.0 0.076 12.7 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.12 EKX55206.1 - 1.8e-06 28.0 0.0 0.0064 16.4 0.0 2.9 2 0 0 2 2 2 2 NACHT domain ATPase_2 PF01637.18 EKX55206.1 - 1.2e-05 25.3 5.8 0.75 9.7 0.0 4.5 3 2 0 4 4 4 2 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EKX55206.1 - 3.2e-05 24.3 0.0 0.08 13.3 0.0 3.0 2 0 0 2 2 2 1 RNA helicase Roc PF08477.13 EKX55206.1 - 4.9e-05 23.5 0.0 0.023 14.9 0.0 2.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 EKX55206.1 - 7.2e-05 23.0 6.2 0.016 15.4 0.0 4.2 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.6 EKX55206.1 - 8.2e-05 23.2 0.5 0.23 12.0 0.0 3.3 3 0 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 EKX55206.1 - 0.00015 21.7 1.1 0.61 10.0 0.0 3.8 2 1 2 5 5 5 2 RsgA GTPase ResIII PF04851.15 EKX55206.1 - 0.00021 21.4 0.0 0.06 13.4 0.0 3.5 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit RuvB_N PF05496.12 EKX55206.1 - 0.00024 20.9 1.8 1.2 8.9 0.0 4.2 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EKX55206.1 - 0.00028 20.3 0.8 0.55 9.6 0.1 3.7 3 1 0 3 3 2 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EKX55206.1 - 0.00029 20.8 0.0 0.95 9.5 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE DNA_pol3_delta2 PF13177.6 EKX55206.1 - 0.00084 19.2 0.0 0.88 9.3 0.0 3.6 3 0 0 3 3 3 1 DNA polymerase III, delta subunit ABC_tran PF00005.27 EKX55206.1 - 0.0014 19.1 1.1 0.32 11.5 0.0 3.6 3 0 0 3 3 3 1 ABC transporter Zeta_toxin PF06414.12 EKX55206.1 - 0.0016 17.8 1.2 0.13 11.6 0.0 3.5 4 0 0 4 4 3 1 Zeta toxin AAA_24 PF13479.6 EKX55206.1 - 0.0018 18.0 0.0 1 9.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 EKX55206.1 - 0.0023 17.8 0.1 0.13 12.2 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MutS_V PF00488.21 EKX55206.1 - 0.013 15.5 0.1 4.2 7.4 0.0 2.5 1 1 1 2 2 2 0 MutS domain V Torsin PF06309.11 EKX55206.1 - 0.015 15.4 0.0 0.089 12.9 0.0 2.2 2 0 0 2 2 2 0 Torsin DUF87 PF01935.17 EKX55206.1 - 0.052 13.6 0.0 0.052 13.6 0.0 4.2 3 2 0 3 3 3 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 EKX55206.1 - 0.066 13.3 0.1 16 5.6 0.0 3.8 4 1 0 4 4 3 0 50S ribosome-binding GTPase AAA_25 PF13481.6 EKX55206.1 - 0.092 12.3 0.5 1.7 8.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.9 EKX55206.1 - 0.098 12.4 0.1 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation APS_kinase PF01583.20 EKX55206.1 - 0.14 12.0 2.0 5.4 6.9 0.0 3.8 4 0 0 4 4 4 0 Adenylylsulphate kinase Snapin_Pallidin PF14712.6 EKX55206.1 - 1.5 9.3 0.0 1.5 9.3 0.0 4.9 5 1 2 7 7 6 0 Snapin/Pallidin CENP-F_leu_zip PF10473.9 EKX55206.1 - 3.6 7.6 17.4 2.9 7.9 14.1 2.7 2 0 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 M16C_assoc PF08367.11 EKX55207.1 - 5.9e-71 238.5 0.1 8.9e-71 237.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EKX55207.1 - 3.6e-26 92.3 0.0 1e-23 84.3 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EKX55207.1 - 1.7e-09 37.8 2.7 3.8e-08 33.4 0.0 3.3 4 0 0 4 4 4 1 Insulinase (Peptidase family M16) PsbP PF01789.16 EKX55208.1 - 2.8e-15 56.8 0.3 3.7e-15 56.4 0.3 1.2 1 0 0 1 1 1 1 PsbP Ferlin_C PF16165.5 EKX55208.1 - 0.053 13.5 0.1 0.073 13.0 0.1 1.2 1 0 0 1 1 1 0 Ferlin C-terminus HTH_29 PF13551.6 EKX55210.1 - 0.0033 17.4 0.0 0.012 15.6 0.0 2.0 1 0 0 1 1 1 1 Winged helix-turn helix Terminase_5 PF06056.12 EKX55210.1 - 0.041 13.8 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) GerE PF00196.19 EKX55210.1 - 0.11 12.1 0.5 0.76 9.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family PDZ_6 PF17820.1 EKX55211.1 - 3.1e-12 46.1 0.1 5.7e-05 22.9 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ_2 PF13180.6 EKX55211.1 - 9.4e-09 35.5 0.0 0.0018 18.6 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 EKX55211.1 - 8.9e-07 29.2 0.4 0.0054 17.1 0.1 2.4 2 0 0 2 2 2 2 PDZ domain HTH_29 PF13551.6 EKX55211.1 - 0.055 13.5 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 Winged helix-turn helix ubiquitin PF00240.23 EKX55212.1 - 5.5e-08 32.4 0.0 1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DnaJ PF00226.31 EKX55212.1 - 0.032 14.4 0.1 0.12 12.5 0.0 2.1 2 1 0 2 2 2 0 DnaJ domain Cupin_2 PF07883.11 EKX55213.1 - 0.0024 17.6 0.0 0.0057 16.3 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EKX55213.1 - 0.084 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Cupin DUF3343 PF11823.8 EKX55213.1 - 1.1 8.7 3.5 0.55 9.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) FpoO PF10621.9 EKX55214.1 - 0.079 13.3 0.7 0.25 11.7 0.7 1.8 1 0 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO DUF3560 PF12083.8 EKX55214.1 - 0.14 12.3 2.6 0.11 12.6 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3560) Phos_pyr_kin PF08543.12 EKX55216.1 - 9e-89 297.1 0.3 1.4e-88 296.4 0.3 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TMP-TENI PF02581.17 EKX55216.1 - 7.5e-61 204.6 0.2 7.5e-61 204.6 0.2 1.9 2 0 0 2 2 2 1 Thiamine monophosphate synthase PfkB PF00294.24 EKX55216.1 - 3.2e-15 56.2 0.3 5.5e-15 55.4 0.2 1.5 2 0 0 2 2 2 1 pfkB family carbohydrate kinase PsiE PF06146.12 EKX55216.1 - 0.041 14.3 0.1 0.17 12.3 0.0 2.0 2 0 0 2 2 2 0 Phosphate-starvation-inducible E HK PF02110.15 EKX55217.1 - 4.6e-61 206.3 4.4 5.8e-61 206.0 4.4 1.0 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 EKX55217.1 - 0.00011 21.6 0.6 0.00022 20.7 0.6 1.4 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.17 EKX55217.1 - 0.00067 19.2 0.2 0.00088 18.8 0.2 1.1 1 0 0 1 1 1 1 Carbohydrate kinase REJ PF02010.15 EKX55218.1 - 2.6e-07 29.8 0.2 2.6e-07 29.8 0.2 2.2 3 0 0 3 3 3 1 REJ domain Big_9 PF17963.1 EKX55218.1 - 8.6e-07 29.6 11.7 0.037 14.8 0.2 7.3 6 0 0 6 6 6 2 Bacterial Ig domain TIG PF01833.24 EKX55218.1 - 0.00022 21.2 3.2 0.065 13.3 0.1 4.4 3 0 0 3 3 3 2 IPT/TIG domain Cadherin_4 PF17803.1 EKX55218.1 - 0.0032 18.0 12.1 0.5 11.0 0.4 5.9 5 0 0 5 5 5 2 Bacterial cadherin-like domain Cadherin_3 PF16184.5 EKX55218.1 - 0.011 15.7 5.4 4.5 7.3 0.0 5.6 5 0 0 5 5 5 0 Cadherin-like Reticulon PF02453.17 EKX55218.1 - 9.3 6.2 11.5 0.24 11.4 1.3 2.6 2 0 0 2 2 2 0 Reticulon 2OG-FeII_Oxy_3 PF13640.6 EKX55219.1 - 1.2e-09 38.9 0.3 3.1e-09 37.6 0.0 1.8 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 EKX55219.1 - 0.13 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus C4/C10 protein TRM PF02005.16 EKX55220.1 - 5e-64 216.8 0.0 6e-64 216.6 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_3 PF01596.17 EKX55220.1 - 0.016 14.4 0.0 0.033 13.3 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Met_10 PF02475.16 EKX55220.1 - 0.023 14.4 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Rubredoxin_2 PF18073.1 EKX55220.1 - 6.3 6.6 7.9 2.4 8.0 2.4 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain RINT1_TIP1 PF04437.13 EKX55221.1 - 0.0074 15.2 0.1 0.072 12.0 0.0 2.1 2 0 0 2 2 2 1 RINT-1 / TIP-1 family DUF4838 PF16126.5 EKX55221.1 - 0.09 12.1 0.1 0.18 11.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4838) Peptidase_C65 PF10275.9 EKX55221.1 - 0.42 10.0 2.3 1.3 8.4 0.1 2.4 2 1 0 2 2 2 0 Peptidase C65 Otubain TMPIT PF07851.13 EKX55221.1 - 0.58 9.4 2.6 0.75 9.0 0.1 2.2 2 0 0 2 2 2 0 TMPIT-like protein Val_tRNA-synt_C PF10458.9 EKX55221.1 - 2 8.7 8.1 2 8.8 0.2 3.5 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm DUF2203 PF09969.9 EKX55221.1 - 2.1 9.1 6.7 2.3 9.0 1.1 3.3 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2203) DUF1090 PF06476.12 EKX55221.1 - 2.8 8.1 8.8 19 5.4 2.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1090) DHC_N1 PF08385.12 EKX55223.1 - 1.1e-161 539.3 17.7 1.1e-161 539.3 17.7 3.5 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 EKX55223.1 - 2.9e-77 260.5 14.6 2.9e-77 260.5 14.6 4.9 5 0 0 5 5 5 2 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 EKX55223.1 - 5.9e-31 107.6 0.4 1.3e-30 106.5 0.4 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region EF-hand_12 PF17901.1 EKX55223.1 - 0.00064 20.1 0.2 0.0038 17.7 0.0 2.5 2 0 0 2 2 2 1 EF-hand fold domain AAA_18 PF13238.6 EKX55223.1 - 0.009 16.6 0.0 0.14 12.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain Radical_SAM PF04055.21 EKX55223.1 - 0.68 10.3 2.7 4.4 7.7 0.2 3.4 3 0 0 3 3 3 0 Radical SAM superfamily LysM PF01476.20 EKX55225.1 - 0.00075 19.5 0.3 0.94 9.6 0.0 3.2 3 0 0 3 3 3 2 LysM domain Myb_DNA-binding PF00249.31 EKX55227.1 - 0.00065 19.8 0.0 0.00098 19.3 0.0 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain TIG PF01833.24 EKX55228.1 - 5.1e-48 161.1 4.4 8.8e-11 41.7 0.0 6.7 6 0 0 6 6 6 5 IPT/TIG domain Kelch_4 PF13418.6 EKX55228.1 - 2e-32 110.9 5.3 2.5e-08 33.8 0.0 7.1 4 1 2 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EKX55228.1 - 2.6e-23 81.5 5.8 1.9e-05 24.5 0.0 6.9 6 1 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 EKX55228.1 - 1.8e-17 63.2 15.8 0.001 19.3 0.0 9.0 9 1 0 9 9 9 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EKX55228.1 - 1.1e-16 60.4 6.4 0.011 15.9 0.1 7.5 6 1 1 7 7 7 5 Kelch motif Lectin_C PF00059.21 EKX55228.1 - 2.5e-12 47.5 0.3 7.2e-08 33.1 0.3 3.0 2 0 0 2 2 2 2 Lectin C-type domain Kelch_1 PF01344.25 EKX55228.1 - 3.8e-12 45.6 2.2 0.051 13.2 0.0 6.3 6 0 0 6 6 6 3 Kelch motif Chordopox_A33R PF05966.12 EKX55228.1 - 0.0028 17.0 0.7 0.0049 16.2 0.1 1.7 2 0 0 2 2 2 1 Chordopoxvirus A33R protein TMEM154 PF15102.6 EKX55228.1 - 0.0091 15.9 0.7 0.0091 15.9 0.7 1.8 2 0 0 2 2 2 1 TMEM154 protein family Methyltrans_SAM PF10672.9 EKX55229.1 - 2.2e-13 50.1 0.0 9.5e-13 47.9 0.0 1.8 1 1 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Cons_hypoth95 PF03602.15 EKX55229.1 - 3.9e-05 23.4 0.2 0.00064 19.4 0.0 2.4 2 1 0 2 2 2 1 Conserved hypothetical protein 95 Methyltr_RsmB-F PF01189.17 EKX55229.1 - 7.7e-05 22.4 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F PUA_3 PF17785.1 EKX55229.1 - 0.00056 19.7 0.0 0.034 13.9 0.0 2.6 1 1 1 2 2 2 1 PUA-like domain Methyltransf_15 PF09445.10 EKX55229.1 - 0.00088 18.9 0.0 0.016 14.8 0.0 2.2 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 EKX55229.1 - 0.0031 17.2 0.0 0.0067 16.1 0.0 1.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.6 EKX55229.1 - 0.0079 16.0 0.0 0.021 14.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX55229.1 - 0.042 14.6 0.1 0.13 13.0 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EKX55229.1 - 0.12 11.7 0.3 0.31 10.4 0.3 1.6 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Aldedh PF00171.22 EKX55230.1 - 0.056 12.0 1.3 0.075 11.5 1.3 1.2 1 0 0 1 1 1 0 Aldehyde dehydrogenase family ZYG-11_interact PF05884.12 EKX55230.1 - 0.19 11.1 1.5 0.27 10.6 1.5 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 UPF0052 PF01933.18 EKX55232.1 - 1e-40 139.8 0.0 1.3e-40 139.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Utp11 PF03998.13 EKX55233.1 - 7.4e-68 229.1 27.7 8.8e-68 228.9 27.7 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 EKX55233.1 - 0.79 9.0 3.5 0.57 9.5 0.1 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 F5_F8_type_C PF00754.25 EKX55234.1 - 3.6e-17 62.7 27.7 0.0025 17.9 0.2 7.9 6 2 2 8 8 8 5 F5/8 type C domain EGF_2 PF07974.13 EKX55234.1 - 1e-11 45.0 164.7 0.00092 19.5 14.8 11.0 11 0 0 11 11 11 7 EGF-like domain EGF_Tenascin PF18720.1 EKX55234.1 - 0.0015 18.5 12.1 0.0015 18.5 12.1 8.2 8 0 0 8 8 8 5 Tenascin EGF domain Kisspeptin PF15152.6 EKX55234.1 - 0.092 13.5 1.0 42 5.0 0.0 3.4 3 0 0 3 3 3 0 Kisspeptin DUF3956 PF13104.6 EKX55234.1 - 0.12 12.5 0.8 26 5.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3956) tRNA-synt_1_2 PF13603.6 EKX55236.1 - 2.3e-65 219.6 0.0 3.9e-65 218.8 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1 PF00133.22 EKX55236.1 - 8.4e-60 202.7 13.1 7.2e-46 156.6 5.8 5.6 2 1 2 4 4 4 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EKX55236.1 - 9e-27 93.8 2.3 3.6e-18 65.5 0.0 4.0 4 1 1 5 5 5 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EKX55236.1 - 2.9e-19 69.5 0.8 4.1e-18 65.8 0.8 2.3 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EKX55236.1 - 0.0016 17.9 0.0 0.77 9.0 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EKX55236.1 - 0.0091 15.0 0.1 0.077 11.9 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (K) WW PF00397.26 EKX55237.1 - 8.4e-10 38.6 1.7 2.1e-09 37.3 1.7 1.8 1 0 0 1 1 1 1 WW domain DUF4407 PF14362.6 EKX55237.1 - 0.028 13.8 9.6 0.042 13.2 9.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cnn_1N PF07989.11 EKX55237.1 - 0.034 14.3 12.2 0.035 14.3 10.5 1.9 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 Phage_HK97_TLTM PF06120.11 EKX55237.1 - 0.038 13.2 8.3 0.064 12.4 8.3 1.3 1 0 0 1 1 1 0 Tail length tape measure protein FliS PF02561.14 EKX55237.1 - 0.048 13.9 2.4 0.11 12.8 2.4 1.6 1 0 0 1 1 1 0 Flagellar protein FliS APG6_N PF17675.1 EKX55237.1 - 0.056 14.0 19.8 0.12 12.9 19.8 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Atg14 PF10186.9 EKX55237.1 - 0.061 12.4 14.2 0.096 11.8 14.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2514 PF10721.9 EKX55237.1 - 0.069 13.2 4.7 0.13 12.2 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Fez1 PF06818.15 EKX55237.1 - 0.12 12.8 14.0 0.038 14.4 10.8 1.8 2 0 0 2 2 2 0 Fez1 HMMR_N PF15905.5 EKX55237.1 - 0.15 11.5 18.6 0.27 10.7 18.6 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal V_ATPase_I PF01496.19 EKX55237.1 - 0.34 8.8 5.9 0.45 8.4 5.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Filament PF00038.21 EKX55237.1 - 0.34 10.4 17.3 0.94 9.0 17.3 1.6 1 1 0 1 1 1 0 Intermediate filament protein Phage_GPO PF05929.11 EKX55237.1 - 0.35 10.5 11.5 0.64 9.6 11.5 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2730 PF10805.8 EKX55237.1 - 0.38 10.9 2.9 1.1 9.4 2.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2730) UPF0231 PF06062.11 EKX55237.1 - 0.46 10.8 8.0 0.78 10.0 7.4 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0231) HlyD_2 PF12700.7 EKX55237.1 - 0.5 9.0 10.4 0.75 8.5 10.4 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Golgin_A5 PF09787.9 EKX55237.1 - 0.65 9.4 17.1 1.1 8.6 17.1 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF1515 PF07439.11 EKX55237.1 - 1.4 9.0 3.9 3.4 7.7 3.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DUF812 PF05667.11 EKX55237.1 - 1.4 7.7 17.4 2.6 6.8 17.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) HOOK PF05622.12 EKX55237.1 - 1.5 6.9 19.2 1.3 7.0 17.0 1.7 1 1 1 2 2 2 0 HOOK protein FliJ PF02050.16 EKX55237.1 - 1.7 8.9 17.6 4.1 7.6 17.6 1.7 1 0 0 1 1 1 0 Flagellar FliJ protein DUF724 PF05266.14 EKX55237.1 - 2.6 7.8 15.9 5.5 6.8 15.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ADIP PF11559.8 EKX55237.1 - 2.7 8.1 21.2 9.6 6.3 9.7 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding HR1 PF02185.16 EKX55237.1 - 3.5 7.8 17.6 1.7e+02 2.4 17.6 3.2 1 1 0 1 1 1 0 Hr1 repeat DUF3584 PF12128.8 EKX55237.1 - 3.7 4.9 18.0 5.1 4.5 18.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3807 PF12720.7 EKX55237.1 - 4.8 7.4 13.3 15 5.8 13.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Spc7 PF08317.11 EKX55237.1 - 5.9 5.7 21.8 10 4.9 21.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-F_N PF10481.9 EKX55237.1 - 6.1 6.4 21.7 0.48 10.0 16.1 1.8 2 0 0 2 2 2 0 Cenp-F N-terminal domain Fib_alpha PF08702.10 EKX55237.1 - 8.7 6.5 16.9 1.9 8.7 4.7 2.8 2 1 1 3 3 2 0 Fibrinogen alpha/beta chain family Baculo_FP PF03258.14 EKX55239.1 - 0.22 11.6 1.5 0.38 10.9 1.5 1.3 1 0 0 1 1 1 0 Baculovirus FP protein GNT-I PF03071.15 EKX55242.1 - 1.1e-11 44.2 0.3 3.4e-11 42.6 0.0 1.8 2 0 0 2 2 2 1 GNT-I family DUF1664 PF07889.12 EKX55243.1 - 2.3e-10 40.6 40.7 0.00026 21.0 7.0 7.2 5 2 2 7 7 7 3 Protein of unknown function (DUF1664) FapA PF03961.13 EKX55243.1 - 6.3e-10 38.3 21.3 0.00098 17.8 0.4 5.0 3 2 2 5 5 5 3 Flagellar Assembly Protein A PDZ_2 PF13180.6 EKX55243.1 - 2.1e-08 34.4 0.9 0.00087 19.6 0.1 3.4 2 1 0 2 2 2 2 PDZ domain PDZ PF00595.24 EKX55243.1 - 9.5e-08 32.3 0.1 0.023 15.0 0.0 3.0 2 1 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 EKX55243.1 - 1.2e-06 28.2 3.7 0.006 16.4 0.3 2.9 3 0 0 3 3 2 2 PDZ domain ATG16 PF08614.11 EKX55243.1 - 2.1e-05 24.8 9.2 2.1e-05 24.8 9.2 5.4 5 1 0 5 5 5 2 Autophagy protein 16 (ATG16) Cyclin_C_2 PF16899.5 EKX55243.1 - 9.8e-05 22.7 0.1 62 4.1 0.0 5.9 5 2 1 6 6 5 0 Cyclin C-terminal domain HMMR_N PF15905.5 EKX55243.1 - 0.00013 21.5 52.7 0.094 12.2 8.0 5.2 5 0 0 5 5 5 3 Hyaluronan mediated motility receptor N-terminal DUF3991 PF13154.6 EKX55243.1 - 0.00017 21.9 0.1 48 4.4 0.0 5.0 5 0 0 5 5 4 0 Protein of unknown function (DUF3991) Golgin_A5 PF09787.9 EKX55243.1 - 0.00023 20.8 49.8 0.034 13.6 9.4 5.9 4 1 1 6 6 6 2 Golgin subfamily A member 5 Tricorn_PDZ PF14685.6 EKX55243.1 - 0.00023 21.1 1.0 0.65 10.0 0.1 2.5 2 0 0 2 2 2 2 Tricorn protease PDZ domain Spc7 PF08317.11 EKX55243.1 - 0.00024 20.1 56.1 0.0016 17.4 10.6 5.1 5 0 0 5 5 5 3 Spc7 kinetochore protein Taxilin PF09728.9 EKX55243.1 - 0.00034 19.9 44.9 0.17 11.0 12.4 4.2 3 1 1 4 4 4 2 Myosin-like coiled-coil protein DUF812 PF05667.11 EKX55243.1 - 0.0011 18.0 41.1 0.056 12.3 9.3 4.5 5 0 0 5 5 5 3 Protein of unknown function (DUF812) zf-C4H2 PF10146.9 EKX55243.1 - 0.002 18.5 8.6 0.002 18.5 8.6 4.3 5 0 0 5 5 4 1 Zinc finger-containing protein GAS PF13851.6 EKX55243.1 - 0.0022 17.4 56.7 0.051 12.9 6.9 6.4 6 1 0 6 6 5 3 Growth-arrest specific micro-tubule binding DUF3584 PF12128.8 EKX55243.1 - 0.0022 15.6 49.4 0.08 10.5 13.6 3.7 1 1 2 4 4 4 4 Protein of unknown function (DUF3584) PspA_IM30 PF04012.12 EKX55243.1 - 0.0029 17.2 0.4 0.0029 17.2 0.4 5.5 3 2 1 4 4 3 2 PspA/IM30 family Cauli_AT PF03233.13 EKX55243.1 - 0.0036 17.2 34.7 0.71 9.8 5.2 5.9 5 2 0 5 5 5 1 Aphid transmission protein IFT57 PF10498.9 EKX55243.1 - 0.0049 15.9 6.8 0.0049 15.9 6.8 4.4 4 1 1 5 5 5 2 Intra-flagellar transport protein 57 Fib_alpha PF08702.10 EKX55243.1 - 0.011 15.9 39.5 0.028 14.6 0.6 6.3 5 3 1 6 6 6 0 Fibrinogen alpha/beta chain family Thymidylat_synt PF00303.19 EKX55243.1 - 0.023 13.8 0.4 0.048 12.8 0.4 1.5 1 0 0 1 1 1 0 Thymidylate synthase BST2 PF16716.5 EKX55243.1 - 0.024 15.2 2.5 0.024 15.2 2.5 7.9 6 3 2 8 8 7 0 Bone marrow stromal antigen 2 Seryl_tRNA_N PF02403.22 EKX55243.1 - 0.03 14.6 56.1 0.53 10.5 7.2 7.5 5 2 2 7 7 7 0 Seryl-tRNA synthetase N-terminal domain Alpha-2-MRAP_C PF06401.11 EKX55243.1 - 0.031 14.2 49.4 0.24 11.3 1.5 7.4 6 1 1 7 7 7 0 Alpha-2-macroglobulin RAP, C-terminal domain DUF4407 PF14362.6 EKX55243.1 - 0.055 12.8 48.7 0.5 9.7 13.1 5.1 1 1 3 4 4 3 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.8 EKX55243.1 - 0.056 13.7 58.9 0.16 12.2 8.7 7.1 5 2 1 6 6 6 0 TATA element modulatory factor 1 TATA binding TolA_bind_tri PF16331.5 EKX55243.1 - 0.069 13.2 33.2 3.9 7.6 5.1 8.3 7 1 2 9 9 9 0 TolA binding protein trimerisation DUF3450 PF11932.8 EKX55243.1 - 0.078 12.3 33.3 0.97 8.7 2.0 6.4 5 2 2 7 7 7 0 Protein of unknown function (DUF3450) Fez1 PF06818.15 EKX55243.1 - 0.11 12.9 52.5 0.27 11.7 6.0 5.0 1 1 2 4 4 4 0 Fez1 TFIIF_beta PF02270.15 EKX55243.1 - 0.12 12.6 9.3 1.2e+02 2.9 0.0 5.4 5 0 0 5 5 5 0 TFIIF, beta subunit HTH domain Mod_r PF07200.13 EKX55243.1 - 0.12 12.4 50.5 2.1 8.5 0.1 6.8 5 3 0 5 5 5 0 Modifier of rudimentary (Mod(r)) protein Jnk-SapK_ap_N PF09744.9 EKX55243.1 - 0.14 12.4 53.5 0.2 11.9 7.3 6.0 5 1 0 5 5 5 0 JNK_SAPK-associated protein-1 Bap31_Bap29_C PF18035.1 EKX55243.1 - 0.22 11.6 0.1 0.22 11.6 0.1 10.7 9 5 0 9 9 4 0 Bap31/Bap29 cytoplasmic coiled-coil domain Surfac_D-trimer PF09006.11 EKX55243.1 - 0.25 11.3 15.7 95 3.0 0.0 9.4 12 0 0 12 12 11 0 Lung surfactant protein D coiled-coil trimerisation Baculo_PEP_C PF04513.12 EKX55243.1 - 0.28 11.2 10.3 0.18 11.8 1.4 4.2 4 1 0 4 4 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cluap1 PF10234.9 EKX55243.1 - 0.29 10.5 38.8 0.85 9.0 4.5 5.7 5 1 0 5 5 5 0 Clusterin-associated protein-1 MetOD2 PF18548.1 EKX55243.1 - 0.32 11.1 29.8 30 4.8 0.1 8.0 6 1 2 8 8 8 0 Metanogen output domain 2 HrpB7 PF09486.10 EKX55243.1 - 0.34 11.3 43.7 0.67 10.3 6.1 6.5 4 2 1 5 5 5 0 Bacterial type III secretion protein (HrpB7) ERM PF00769.19 EKX55243.1 - 1.1 9.0 52.9 0.72 9.6 12.9 4.3 2 1 0 3 3 3 0 Ezrin/radixin/moesin family SH3BP5 PF05276.14 EKX55243.1 - 1.3 8.8 43.0 0.37 10.5 5.1 6.2 5 2 2 7 7 7 0 SH3 domain-binding protein 5 (SH3BP5) DUF1612 PF07756.12 EKX55243.1 - 1.4 9.2 5.3 0.55 10.5 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1612) Filament PF00038.21 EKX55243.1 - 1.6 8.2 46.3 0.058 13.0 8.1 5.4 5 1 0 5 5 5 0 Intermediate filament protein FliJ PF02050.16 EKX55243.1 - 2.1 8.6 43.6 8.4 6.6 0.8 7.4 5 3 3 8 8 8 0 Flagellar FliJ protein Exonuc_VII_L PF02601.15 EKX55243.1 - 3.4 7.1 36.2 1.8e+04 -17.7 35.9 4.0 1 1 0 1 1 0 0 Exonuclease VII, large subunit Bacillus_HBL PF05791.11 EKX55243.1 - 4.4 7.1 28.2 2.9 7.7 0.6 5.6 5 1 1 6 6 6 0 Bacillus haemolytic enterotoxin (HBL) Toxin_20 PF08089.11 EKX55243.1 - 5.9 7.1 38.0 3.3 7.9 0.3 6.0 7 0 0 7 7 4 0 Huwentoxin-II family EzrA PF06160.12 EKX55243.1 - 5.9 4.9 35.1 0.016 13.4 3.4 4.5 5 0 0 5 5 5 0 Septation ring formation regulator, EzrA ApoO PF09769.9 EKX55243.1 - 6.9 6.6 8.9 2.1 8.3 1.1 3.9 5 1 1 6 6 3 0 Apolipoprotein O OmpH PF03938.14 EKX55243.1 - 7 7.0 56.3 0.24 11.7 6.3 6.9 1 1 5 6 6 5 0 Outer membrane protein (OmpH-like) Tropomyosin_1 PF12718.7 EKX55243.1 - 8.8 6.5 58.2 0.15 12.2 7.4 6.5 5 1 0 5 5 5 0 Tropomyosin like Cob_adeno_trans PF01923.18 EKX55243.1 - 8.9 6.4 25.9 6.5 6.9 1.3 5.7 3 1 1 5 5 5 0 Cobalamin adenosyltransferase GST_N_2 PF13409.6 EKX55244.1 - 8.8e-12 45.2 0.0 1.4e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EKX55244.1 - 2.2e-09 37.2 0.0 4.1e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EKX55244.1 - 0.00052 20.2 0.0 0.00063 19.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EKX55244.1 - 0.00078 19.2 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EKX55244.1 - 0.022 15.2 0.0 0.21 12.0 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EKX55244.1 - 0.022 14.9 0.0 0.031 14.5 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF1192 PF06698.11 EKX55244.1 - 0.044 13.9 0.0 0.082 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Phyto_Pns9_10 PF05878.11 EKX55244.1 - 0.2 10.8 0.0 0.24 10.5 0.0 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 PUF PF00806.19 EKX55245.1 - 0.082 12.6 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat RRM_1 PF00076.22 EKX55246.1 - 8.1e-09 35.2 0.1 5.2e-07 29.4 0.1 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EKX55246.1 - 0.039 14.1 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif GRP PF07172.11 EKX55246.1 - 1.1 10.0 13.6 2.3 9.0 13.5 1.6 1 1 0 1 1 1 0 Glycine rich protein family PDZ PF00595.24 EKX55247.1 - 4e-06 27.1 0.0 5.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX55247.1 - 1.6e-05 24.7 0.0 3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX55247.1 - 0.00011 22.5 0.0 0.00017 21.8 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Glyco_transf_15 PF01793.16 EKX55248.1 - 3.2e-23 82.5 0.0 5.1e-23 81.8 0.0 1.3 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase YjgF_endoribonc PF14588.6 EKX55248.1 - 0.17 12.0 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease TPR_1 PF00515.28 EKX55249.1 - 0.00041 20.1 1.0 0.12 12.3 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX55249.1 - 0.0011 18.9 3.9 0.11 12.6 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF357 PF04010.13 EKX55249.1 - 0.032 14.3 0.4 0.43 10.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF357) TPR_7 PF13176.6 EKX55249.1 - 0.07 13.2 1.1 4.1 7.6 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TatD_DNase PF01026.21 EKX55250.1 - 8.5e-44 149.8 0.0 1.2e-43 149.4 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase RINGv PF12906.7 EKX55250.1 - 1.1e-07 31.8 7.1 1.1e-07 31.8 7.1 2.1 2 0 0 2 2 2 1 RING-variant domain PHD PF00628.29 EKX55250.1 - 0.3 11.0 6.0 0.81 9.6 6.0 1.8 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 EKX55250.1 - 0.43 10.8 3.8 1.4 9.2 3.9 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_2 PF13639.6 EKX55250.1 - 0.5 10.8 6.8 1.4 9.3 6.8 1.9 1 0 0 1 1 1 0 Ring finger domain Glycos_transf_2 PF00535.26 EKX55251.1 - 2.3e-17 63.3 0.0 4.4e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EKX55251.1 - 0.054 13.4 0.0 0.48 10.3 0.0 2.4 2 1 0 2 2 2 0 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EKX55251.1 - 0.071 12.6 0.1 1.2 8.5 0.1 2.6 1 1 0 1 1 1 0 Glycosyltransferase like family 2 PDZ PF00595.24 EKX55252.1 - 1.6e-05 25.1 0.0 3.8e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 EKX55252.1 - 0.00018 21.3 0.0 0.00038 20.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX55252.1 - 0.00036 20.8 0.2 0.0026 18.0 0.0 2.4 2 1 1 3 3 3 1 PDZ domain Fez1 PF06818.15 EKX55252.1 - 0.0043 17.5 15.0 0.0069 16.9 15.0 1.2 1 0 0 1 1 1 1 Fez1 AAA_23 PF13476.6 EKX55252.1 - 0.0058 17.2 7.2 0.0073 16.8 7.2 1.2 1 0 0 1 1 1 1 AAA domain KASH_CCD PF14662.6 EKX55252.1 - 0.0082 16.0 20.5 0.026 14.4 8.6 2.5 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 EKX55252.1 - 0.087 11.7 16.5 0.13 11.1 16.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.6 EKX55252.1 - 0.14 11.5 21.7 0.23 10.8 21.7 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 EKX55252.1 - 0.16 12.1 20.3 0.27 11.5 20.3 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF3435 PF11917.8 EKX55252.1 - 0.19 10.6 9.6 0.28 10.1 9.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3435) OEP PF02321.18 EKX55252.1 - 0.2 11.4 12.9 0.32 10.8 12.4 1.6 1 1 0 1 1 1 0 Outer membrane efflux protein DivIC PF04977.15 EKX55252.1 - 0.32 10.8 18.8 0.097 12.4 2.5 4.6 3 1 2 5 5 5 0 Septum formation initiator TMPIT PF07851.13 EKX55252.1 - 0.32 10.2 10.7 0.42 9.8 10.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF724 PF05266.14 EKX55252.1 - 0.42 10.4 14.6 0.63 9.8 7.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) PRKG1_interact PF15898.5 EKX55252.1 - 0.48 11.3 20.5 1.4 9.8 3.9 2.6 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Phlebovirus_NSM PF07246.11 EKX55252.1 - 0.76 9.1 9.5 0.31 10.4 6.4 1.8 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M DUF1664 PF07889.12 EKX55252.1 - 0.77 9.8 9.2 1.2 9.2 4.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Phage_GPO PF05929.11 EKX55252.1 - 0.91 9.1 7.6 1.2 8.7 7.6 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Bap31_Bap29_C PF18035.1 EKX55252.1 - 1 9.4 19.3 0.6 10.2 1.7 2.8 2 1 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Fmp27_WPPW PF10359.9 EKX55252.1 - 1.2 8.0 11.1 1.5 7.6 11.1 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CENP-H PF05837.12 EKX55252.1 - 1.7 9.1 16.5 1.8 9.0 15.5 1.6 1 1 0 1 1 1 0 Centromere protein H (CENP-H) ADIP PF11559.8 EKX55252.1 - 1.9 8.6 21.0 0.18 11.9 6.9 2.5 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding HIP1_clath_bdg PF16515.5 EKX55252.1 - 2.2 8.9 20.3 0.53 10.9 3.5 2.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Seryl_tRNA_N PF02403.22 EKX55252.1 - 2.3 8.5 17.5 1 9.6 10.9 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4200 PF13863.6 EKX55252.1 - 3.8 7.9 23.9 0.81 10.1 13.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) CRAL_TRIO PF00650.20 EKX55253.1 - 9.2e-11 41.7 0.0 1.3e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain S4 PF01479.25 EKX55253.1 - 0.094 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 S4 domain NAD_binding_8 PF13450.6 EKX55255.1 - 7.1e-11 42.2 1.8 2.4e-10 40.5 1.8 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EKX55255.1 - 9.8e-08 31.7 8.7 2.6e-05 23.7 0.3 4.6 4 1 1 5 5 5 2 Flavin containing amine oxidoreductase DAO PF01266.24 EKX55255.1 - 7.3e-07 29.1 2.4 1.7e-06 27.9 2.4 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EKX55255.1 - 0.00038 19.8 0.6 0.00066 19.0 0.6 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 EKX55255.1 - 0.00083 18.3 0.3 0.0016 17.4 0.3 1.4 1 0 0 1 1 1 1 MCRA family NAD_binding_9 PF13454.6 EKX55255.1 - 0.0036 17.3 0.2 0.011 15.7 0.2 1.9 1 0 0 1 1 1 1 FAD-NAD(P)-binding Gelsolin PF00626.22 EKX55255.1 - 0.0087 15.9 0.0 0.029 14.3 0.0 1.9 1 0 0 1 1 1 1 Gelsolin repeat Pyr_redox PF00070.27 EKX55255.1 - 0.011 16.3 1.0 0.034 14.7 1.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EKX55255.1 - 0.059 12.1 1.7 0.15 10.8 1.7 1.6 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 EKX55255.1 - 0.059 12.4 2.2 0.098 11.7 2.2 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 EKX55255.1 - 0.16 11.2 1.3 0.3 10.3 0.6 1.7 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 EKX55255.1 - 0.4 9.7 1.6 0.69 8.9 1.6 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A TPR_12 PF13424.6 EKX55256.1 - 3.9e-13 49.5 0.1 0.0025 18.1 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat PDZ_6 PF17820.1 EKX55256.1 - 4.4e-07 29.6 0.2 9.3e-07 28.6 0.2 1.5 1 0 0 1 1 1 1 PDZ domain TPR_10 PF13374.6 EKX55256.1 - 1.5e-06 27.9 0.3 0.048 13.5 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat PDZ PF00595.24 EKX55256.1 - 4.3e-06 27.0 0.0 9.6e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain TPR_2 PF07719.17 EKX55256.1 - 3.2e-05 23.7 1.1 3.2 8.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat SNAP PF14938.6 EKX55256.1 - 6.5e-05 22.5 0.1 9.6e-05 21.9 0.1 1.2 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_1 PF00515.28 EKX55256.1 - 0.00022 20.9 0.5 1.1 9.2 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat PDZ_2 PF13180.6 EKX55256.1 - 0.0011 19.2 0.0 0.0024 18.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Lebercilin PF15619.6 EKX55256.1 - 0.0015 18.2 5.7 0.0028 17.4 5.7 1.4 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease SlyX PF04102.12 EKX55256.1 - 0.0023 18.5 2.8 0.048 14.3 0.9 2.6 1 1 1 2 2 2 1 SlyX TraC PF07820.12 EKX55256.1 - 0.0024 18.1 2.0 0.0041 17.4 1.2 1.9 2 0 0 2 2 1 1 TraC-like protein CENP-F_leu_zip PF10473.9 EKX55256.1 - 0.0025 17.8 5.1 0.0057 16.7 5.1 1.6 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_8 PF13181.6 EKX55256.1 - 0.0052 16.9 1.1 7 7.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DivIC PF04977.15 EKX55256.1 - 0.0079 15.9 2.1 1.7 8.5 0.0 2.4 1 1 1 2 2 2 1 Septum formation initiator Fez1 PF06818.15 EKX55256.1 - 0.011 16.2 2.7 0.017 15.6 2.7 1.3 1 0 0 1 1 1 0 Fez1 Snapin_Pallidin PF14712.6 EKX55256.1 - 0.012 16.0 0.8 0.069 13.6 0.7 2.3 1 1 1 2 2 2 0 Snapin/Pallidin Golgin_A5 PF09787.9 EKX55256.1 - 0.013 15.0 2.1 0.022 14.3 2.1 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 ATG16 PF08614.11 EKX55256.1 - 0.014 15.6 3.4 0.025 14.8 3.4 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Tup_N PF08581.10 EKX55256.1 - 0.014 15.6 1.9 0.33 11.3 0.3 3.1 2 1 0 2 2 2 0 Tup N-terminal WEMBL PF05701.11 EKX55256.1 - 0.018 13.8 3.2 0.028 13.1 3.2 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light TPR_6 PF13174.6 EKX55256.1 - 0.018 15.6 1.6 1.4 9.7 0.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF1192 PF06698.11 EKX55256.1 - 0.037 14.1 2.2 0.037 14.1 2.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Phasin PF05597.11 EKX55256.1 - 0.064 13.3 1.0 0.15 12.1 0.4 1.9 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) KASH_CCD PF14662.6 EKX55256.1 - 0.07 13.0 3.5 0.13 12.1 3.5 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Laminin_II PF06009.12 EKX55256.1 - 0.071 13.1 0.8 0.15 12.1 0.8 1.5 1 0 0 1 1 1 0 Laminin Domain II APG6_N PF17675.1 EKX55256.1 - 0.081 13.5 6.8 0.21 12.1 6.8 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region TPR_7 PF13176.6 EKX55256.1 - 0.093 12.8 2.0 15 5.9 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat HIP1_clath_bdg PF16515.5 EKX55256.1 - 0.18 12.5 4.5 4.4 8.0 1.9 2.7 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ZapB PF06005.12 EKX55256.1 - 0.25 11.8 3.2 2.7 8.5 2.4 2.5 1 1 1 2 2 2 0 Cell division protein ZapB Syntaxin_2 PF14523.6 EKX55256.1 - 0.25 11.7 3.1 0.33 11.3 0.2 2.4 3 0 0 3 3 3 0 Syntaxin-like protein RPN7 PF10602.9 EKX55256.1 - 0.29 10.8 4.3 0.69 9.6 0.6 2.7 2 1 1 3 3 3 0 26S proteasome subunit RPN7 UPF0242 PF06785.11 EKX55256.1 - 0.39 10.8 4.0 1.2 9.2 4.1 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Prefoldin_2 PF01920.20 EKX55256.1 - 0.63 10.0 6.2 0.39 10.7 0.8 3.3 5 0 0 5 5 3 0 Prefoldin subunit Seryl_tRNA_N PF02403.22 EKX55256.1 - 1 9.6 4.5 0.84 9.9 0.4 2.5 2 1 1 3 3 2 0 Seryl-tRNA synthetase N-terminal domain Cep57_CLD_2 PF14197.6 EKX55256.1 - 1.1 9.4 6.5 0.76 9.9 2.1 2.6 2 2 0 2 2 2 0 Centrosome localisation domain of PPC89 PDZ_6 PF17820.1 EKX55257.1 - 4.5e-09 36.0 0.4 8.9e-09 35.1 0.4 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX55257.1 - 1.4e-08 34.9 0.1 4.2e-08 33.4 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX55257.1 - 7.6e-08 32.6 0.3 1.9e-07 31.3 0.3 1.7 1 0 0 1 1 1 1 PDZ domain TMCO5 PF14992.6 EKX55257.1 - 0.028 14.0 15.3 0.055 13.0 15.3 1.5 1 0 0 1 1 1 0 TMCO5 family Sbi-IV PF11621.8 EKX55257.1 - 0.063 13.6 0.1 0.063 13.6 0.1 2.7 3 0 0 3 3 3 0 C3 binding domain 4 of IgG-bind protein SBI DUF573 PF04504.14 EKX55257.1 - 2.4 8.9 7.7 0.22 12.2 1.5 2.5 2 1 1 3 3 3 0 Protein of unknown function, DUF573 APG6_N PF17675.1 EKX55257.1 - 4.2 7.9 20.9 0.066 13.7 6.7 3.2 2 1 0 3 3 3 0 Apg6 coiled-coil region Lebercilin PF15619.6 EKX55258.1 - 0.0015 18.2 7.7 0.0015 18.2 7.7 3.5 1 1 3 4 4 4 2 Ciliary protein causing Leber congenital amaurosis disease Plk4_PB2 PF18409.1 EKX55258.1 - 4.1 8.1 21.8 11 6.7 0.2 4.4 2 1 2 4 4 4 0 Polo-like Kinase 4 Polo Box 2 Frag1 PF10277.9 EKX55260.1 - 1.8e-12 47.3 9.6 2.3e-12 46.9 9.6 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF716 PF04819.12 EKX55260.1 - 0.0012 18.5 0.8 0.0012 18.5 0.8 2.4 2 1 0 2 2 2 1 Family of unknown function (DUF716) RibD_C PF01872.17 EKX55261.1 - 3e-24 86.0 0.0 4.1e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain STI1 PF17830.1 EKX55262.1 - 0.013 15.4 2.5 0.024 14.5 1.6 2.0 2 0 0 2 2 2 0 STI1 domain Endonuc-dimeris PF09124.10 EKX55262.1 - 0.056 13.6 0.1 0.4 10.9 0.0 2.1 2 0 0 2 2 2 0 T4 recombination endonuclease VII, dimerisation LRR_6 PF13516.6 EKX55263.1 - 2.3e-14 52.2 3.1 0.00049 19.9 0.1 3.9 3 0 0 3 3 3 3 Leucine Rich repeat LRR_4 PF12799.7 EKX55263.1 - 0.069 13.6 0.3 0.37 11.3 0.2 2.3 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) DUF1374 PF07118.11 EKX55263.1 - 0.12 12.9 0.3 1.7 9.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1374) WASH-7_mid PF14744.6 EKX55263.1 - 0.16 11.1 0.7 0.24 10.4 0.7 1.2 1 0 0 1 1 1 0 WASH complex subunit 7 EGF_CA PF07645.15 EKX55266.1 - 1.2e-08 35.0 30.0 1.3e-06 28.5 6.7 8.9 8 2 1 9 9 9 2 Calcium-binding EGF domain EGF_3 PF12947.7 EKX55266.1 - 4.6e-07 29.9 7.9 4.6e-07 29.9 7.9 9.6 9 1 0 9 9 9 3 EGF domain TSP_1 PF00090.19 EKX55266.1 - 0.00011 22.3 7.5 0.00011 22.3 7.5 5.5 5 0 0 5 5 5 2 Thrombospondin type 1 domain hEGF PF12661.7 EKX55266.1 - 0.00061 20.3 0.5 0.00061 20.3 0.5 9.4 10 0 0 10 10 10 2 Human growth factor-like EGF Ephrin_rec_like PF07699.13 EKX55266.1 - 0.00086 19.0 4.4 0.00086 19.0 4.4 7.3 4 2 1 6 6 6 5 Putative ephrin-receptor like cEGF PF12662.7 EKX55266.1 - 0.0075 16.2 1.9 0.0075 16.2 1.9 9.7 10 2 1 11 11 11 1 Complement Clr-like EGF-like EGF_MSP1_1 PF12946.7 EKX55266.1 - 0.44 10.6 36.2 0.46 10.6 3.9 6.7 5 1 1 6 6 6 0 MSP1 EGF domain 1 Lysine_decarbox PF03641.14 EKX55267.1 - 1.9e-23 83.0 0.0 2.4e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 EKX55267.1 - 4.4e-20 71.8 0.7 5.8e-20 71.5 0.7 1.2 1 0 0 1 1 1 1 SLOG cluster4 family DNA_processg_A PF02481.15 EKX55267.1 - 0.034 13.4 0.1 0.046 13.0 0.1 1.2 1 0 0 1 1 1 0 DNA recombination-mediator protein A OsmC PF02566.19 EKX55268.1 - 1.4e-12 48.0 0.1 1.9e-12 47.5 0.1 1.3 1 1 0 1 1 1 1 OsmC-like protein HAD PF12710.7 EKX55270.1 - 2.1e-21 77.2 0.0 3.4e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EKX55270.1 - 0.0019 18.5 0.0 0.032 14.5 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Patched PF02460.18 EKX55271.1 - 4.4e-58 197.1 16.9 5.7e-36 124.0 0.0 2.4 2 1 0 2 2 2 2 Patched family NPC1_N PF16414.5 EKX55271.1 - 1.7e-34 119.5 5.1 3.8e-34 118.3 5.1 1.6 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Sterol-sensing PF12349.8 EKX55271.1 - 2.3e-29 102.2 6.2 2.1e-17 63.4 1.6 4.2 3 1 1 4 4 4 2 Sterol-sensing domain of SREBP cleavage-activation Tic22 PF04278.12 EKX55272.1 - 5.4e-14 52.2 0.0 7.6e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Tic22-like family HNH PF01844.23 EKX55273.1 - 0.00078 19.6 18.2 0.00097 19.3 3.0 4.4 3 1 0 3 3 3 2 HNH endonuclease zf-C4_ClpX PF06689.13 EKX55273.1 - 0.25 11.2 0.0 0.25 11.2 0.0 4.0 5 1 0 5 5 5 0 ClpX C4-type zinc finger HNH_5 PF14279.6 EKX55273.1 - 0.28 11.1 19.0 0.13 12.2 1.6 4.7 3 2 0 3 3 3 0 HNH endonuclease Lar_restr_allev PF14354.6 EKX55273.1 - 4.3 7.8 15.0 0.5 10.8 1.7 2.9 3 1 0 3 3 3 0 Restriction alleviation protein Lar Acyltransferase PF01553.21 EKX55274.1 - 4.5e-13 49.0 0.0 7.1e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Cyclin_N PF00134.23 EKX55277.1 - 1.2e-06 28.2 0.1 0.062 13.1 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Staygreen PF12638.7 EKX55277.1 - 0.063 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Staygreen protein Pkinase PF00069.25 EKX55278.1 - 2.8e-48 164.6 0.0 3.7e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX55278.1 - 3.2e-47 161.0 0.0 3.9e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EKX55278.1 - 0.0013 18.7 0.0 0.13 12.2 0.0 2.4 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EKX55278.1 - 0.022 13.6 0.0 0.037 12.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Peptidase_S8 PF00082.22 EKX55279.1 - 2.6e-28 99.1 1.1 3.9e-28 98.6 1.1 1.3 1 0 0 1 1 1 1 Subtilase family Rib_5-P_isom_A PF06026.14 EKX55280.1 - 4e-63 212.1 0.1 4.9e-63 211.8 0.1 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Sec7 PF01369.20 EKX55281.1 - 8.8e-23 80.9 0.0 1.5e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sulfotransfer_1 PF00685.27 EKX55282.1 - 2.1e-30 106.1 0.0 2.6e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EKX55282.1 - 5.3e-09 36.8 0.0 9.3e-08 32.7 0.0 2.4 1 1 0 1 1 1 1 Sulfotransferase family Methyltransf_4 PF02390.17 EKX55282.1 - 0.11 12.0 0.1 0.24 10.9 0.1 1.6 1 0 0 1 1 1 0 Putative methyltransferase Peptidase_S49 PF01343.18 EKX55283.1 - 1.4e-57 193.9 6.4 3.5e-21 75.8 0.0 4.2 3 1 1 4 4 4 4 Peptidase family S49 CLP_protease PF00574.23 EKX55283.1 - 7.3e-05 22.7 0.3 0.095 12.6 0.2 2.9 1 1 1 2 2 2 2 Clp protease ECH_1 PF00378.20 EKX55283.1 - 0.00018 20.9 0.2 0.19 11.0 0.0 2.5 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SDH_sah PF01972.16 EKX55283.1 - 0.00028 20.0 0.1 0.00045 19.3 0.1 1.2 1 0 0 1 1 1 1 Serine dehydrogenase proteinase Ank_4 PF13637.6 EKX55284.1 - 7.2e-28 96.6 4.9 5.2e-08 33.3 0.0 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EKX55284.1 - 2.9e-26 91.9 0.3 1.9e-10 41.2 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX55284.1 - 4.4e-23 78.9 5.1 0.0016 18.8 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EKX55284.1 - 9.3e-22 76.8 3.3 1.5e-06 28.4 0.0 4.2 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX55284.1 - 4.1e-21 74.4 6.6 0.00031 21.1 0.9 5.8 6 0 0 6 6 6 5 Ankyrin repeat Epimerase PF01370.21 EKX55286.1 - 0.065 12.7 0.1 0.31 10.5 0.0 1.8 1 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family WD40 PF00400.32 EKX55289.1 - 1.5e-20 73.1 11.5 6.5e-06 26.8 0.4 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX55289.1 - 4.2e-12 46.2 5.4 0.0089 16.3 0.2 6.1 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EKX55289.1 - 0.001 18.9 0.0 1.7 8.7 0.0 3.1 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat IKI3 PF04762.12 EKX55289.1 - 0.0044 15.1 2.3 0.32 9.0 2.1 3.0 1 1 1 2 2 2 1 IKI3 family eIF2A PF08662.11 EKX55289.1 - 0.0061 16.5 0.2 0.21 11.5 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EKX55289.1 - 0.012 14.6 0.2 12 4.8 0.0 3.5 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 EKX55289.1 - 0.031 14.0 1.5 0.64 9.7 0.9 2.9 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain Nbas_N PF15492.6 EKX55289.1 - 0.05 12.9 0.2 0.43 9.9 0.0 2.6 2 2 2 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Mesd PF10185.9 EKX55291.1 - 2.4e-10 40.5 0.1 2.6e-10 40.4 0.1 1.1 1 0 0 1 1 1 1 Chaperone for wingless signalling and trafficking of LDL receptor DUF261 PF03196.13 EKX55291.1 - 0.053 13.6 0.0 0.063 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF261 DUF1039 PF06287.11 EKX55293.1 - 0.029 14.8 0.1 0.11 12.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1039) MutS_V PF00488.21 EKX55294.1 - 4.6e-66 222.4 0.0 1e-65 221.3 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EKX55294.1 - 1.3e-28 100.6 2.9 2.5e-28 99.6 2.9 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EKX55294.1 - 1.3e-27 96.3 0.0 3.4e-27 94.9 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 EKX55294.1 - 4.1e-14 52.7 0.7 7.2e-14 51.9 0.1 1.8 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 EKX55294.1 - 2.3e-06 27.9 0.0 0.0013 19.0 0.0 2.7 1 1 1 2 2 2 2 MutS domain II Big_2 PF02368.18 EKX55294.1 - 0.025 14.4 0.6 0.061 13.2 0.6 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 2) JAKMIP_CC3 PF16034.5 EKX55294.1 - 3.8 7.4 7.4 1.9 8.4 4.3 2.0 2 0 0 2 2 2 0 JAKMIP CC3 domain PseudoU_synth_2 PF00849.22 EKX55295.1 - 1.9e-28 99.5 0.0 3e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 EKX55295.1 - 2e-05 24.2 0.0 3.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 S4 domain RWP-RK PF02042.15 EKX55296.1 - 5.9e-15 55.0 0.6 1.6e-14 53.6 0.2 1.9 2 0 0 2 2 2 1 RWP-RK domain RWP-RK PF02042.15 EKX55298.1 - 3e-14 52.7 0.2 9.3e-14 51.1 0.2 1.9 1 0 0 1 1 1 1 RWP-RK domain Collagen PF01391.18 EKX55299.1 - 6.3e-37 125.1 123.3 4.9e-10 39.0 21.6 5.6 2 1 3 5 5 5 5 Collagen triple helix repeat (20 copies) Troponin PF00992.20 EKX55299.1 - 0.038 14.3 0.1 0.057 13.7 0.1 1.1 1 0 0 1 1 1 0 Troponin Tetraspanin PF00335.20 EKX55300.1 - 6.2e-13 49.0 8.5 6.2e-13 49.0 8.5 1.9 1 1 1 2 2 2 1 Tetraspanin family DUF1043 PF06295.12 EKX55300.1 - 0.0074 16.3 1.3 3.3 7.7 0.1 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1043) DUF1616 PF07760.11 EKX55300.1 - 0.02 14.3 0.2 0.85 8.9 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1616) DUF3278 PF11683.8 EKX55300.1 - 0.048 13.7 0.3 0.048 13.7 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3278) DUF4064 PF13273.6 EKX55300.1 - 0.3 11.4 13.6 0.47 10.8 6.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF5362 PF17319.2 EKX55300.1 - 3 7.8 8.6 2.2 8.1 3.4 2.9 1 1 0 2 2 2 0 Family of unknown function (DUF5362) Glyco_transf_92 PF01697.27 EKX55301.1 - 3.6e-20 72.7 0.4 9.5e-20 71.3 0.4 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 EKX55301.1 - 4.9e-12 46.2 0.1 1.2e-11 45.0 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 LRR_6 PF13516.6 EKX55302.1 - 7e-06 25.7 1.0 0.15 12.2 0.0 4.3 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 EKX55302.1 - 5.1e-05 23.3 0.5 0.22 12.2 0.0 4.2 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_4 PF12799.7 EKX55302.1 - 0.00053 20.3 0.0 2.3 8.8 0.0 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EKX55302.1 - 0.0058 16.5 3.8 0.013 15.4 0.2 2.9 2 1 0 2 2 2 1 F-box-like KELK PF15796.5 EKX55303.1 - 0.0025 18.2 2.7 0.0053 17.2 2.7 1.5 1 0 0 1 1 1 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase Snapin_Pallidin PF14712.6 EKX55303.1 - 0.02 15.3 0.4 0.06 13.8 0.4 1.8 1 0 0 1 1 1 0 Snapin/Pallidin DUF4164 PF13747.6 EKX55303.1 - 0.027 14.8 4.6 0.027 14.8 4.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DivIC PF04977.15 EKX55303.1 - 0.064 13.0 4.4 0.1 12.4 0.9 2.5 2 0 0 2 2 2 0 Septum formation initiator CENP-F_leu_zip PF10473.9 EKX55303.1 - 1.1 9.3 8.8 0.051 13.6 1.4 2.3 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-H PF05837.12 EKX55303.1 - 1.5 9.2 10.4 2.3 8.7 0.9 2.6 2 1 1 3 3 3 0 Centromere protein H (CENP-H) ATG16 PF08614.11 EKX55303.1 - 9.1 6.5 19.4 0.95 9.6 8.4 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) BUD22 PF09073.10 EKX55304.1 - 0.00086 18.8 22.4 0.034 13.5 8.8 2.1 2 0 0 2 2 2 2 BUD22 RCC1 PF00415.18 EKX55306.1 - 2.1e-55 185.1 25.3 5.9e-08 33.2 1.7 7.5 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX55306.1 - 1.1e-29 101.6 54.1 9.3e-09 34.9 3.9 8.3 9 0 0 9 9 9 5 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 EKX55306.1 - 2.1e-05 24.3 0.3 5.8e-05 22.9 0.3 1.8 1 0 0 1 1 1 1 F-box-like DUF4505 PF14956.6 EKX55310.1 - 2.4e-33 115.4 0.2 3.8e-33 114.7 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4505) CHZ PF09649.10 EKX55310.1 - 0.089 12.3 0.1 0.17 11.4 0.1 1.5 1 0 0 1 1 1 0 Histone chaperone domain CHZ ELFV_dehydrog_N PF02812.18 EKX55312.1 - 2.1e-57 192.6 0.0 4e-57 191.7 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 EKX55312.1 - 4.3e-54 183.8 0.3 5e-53 180.3 0.1 2.1 1 1 1 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 EKX55312.1 - 2.4e-05 23.8 0.0 6.4e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 EKX55312.1 - 0.0062 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 EKX55312.1 - 0.019 15.4 0.0 0.038 14.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Bac_GDH PF05088.12 EKX55312.1 - 0.046 11.2 0.0 0.071 10.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase XPG_I_2 PF12813.7 EKX55314.1 - 1.3e-12 47.7 7.6 1.2e-09 38.0 0.3 2.8 3 0 0 3 3 3 2 XPG domain containing DUF5615 PF18480.1 EKX55314.1 - 0.0024 17.6 0.0 0.017 14.9 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF5615) XPG_N PF00752.17 EKX55314.1 - 0.023 15.2 0.0 0.062 13.8 0.0 1.7 1 0 0 1 1 1 0 XPG N-terminal domain Acyl-CoA_dh_2 PF08028.11 EKX55314.1 - 0.29 11.4 1.8 0.75 10.1 1.8 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain PDZ_6 PF17820.1 EKX55315.1 - 1.4e-10 40.8 0.4 3.8e-10 39.4 0.4 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX55315.1 - 1.3e-08 35.1 1.1 1.9e-08 34.5 0.1 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EKX55315.1 - 1.5e-06 28.4 0.1 5.9e-06 26.5 0.0 2.0 2 1 0 2 2 2 1 PDZ domain TPR_MLP1_2 PF07926.12 EKX55315.1 - 2 8.5 36.5 0.021 14.9 23.8 3.2 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein cNMP_binding PF00027.29 EKX55316.1 - 4.9e-06 26.5 0.0 1.1e-05 25.4 0.0 1.6 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Methyltransf_21 PF05050.12 EKX55317.1 - 0.053 13.5 0.1 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase FkbM domain DOT1 PF08123.13 EKX55318.1 - 6.1e-05 22.6 0.0 0.00033 20.2 0.0 1.9 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 EKX55318.1 - 0.022 15.4 0.0 0.04 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 EKX55318.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain IFRD PF05004.13 EKX55319.1 - 0.01 15.0 0.1 0.011 14.9 0.1 1.1 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Mo25 PF08569.11 EKX55319.1 - 0.021 14.2 0.4 0.03 13.7 0.4 1.4 1 1 0 1 1 1 0 Mo25-like Cnd1 PF12717.7 EKX55319.1 - 0.032 14.3 0.9 0.046 13.8 0.9 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EKX55319.1 - 0.032 14.6 0.2 0.26 11.7 0.1 2.3 2 1 0 2 2 2 0 HEAT repeats MOR2-PAG1_C PF14225.6 EKX55319.1 - 0.073 12.9 1.5 0.2 11.5 0.4 1.8 1 1 1 2 2 2 0 Cell morphogenesis C-terminal HEAT PF02985.22 EKX55319.1 - 0.11 12.8 0.7 0.87 10.0 0.0 2.8 3 0 0 3 3 3 0 HEAT repeat Pkinase PF00069.25 EKX55320.1 - 5.9e-73 245.5 0.0 6.6e-73 245.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX55320.1 - 8.3e-50 169.5 0.0 9.3e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX55320.1 - 3.2e-08 32.8 0.0 3.6e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EKX55320.1 - 5.9e-06 25.8 0.5 0.0019 17.5 0.1 2.4 2 1 0 2 2 2 2 Kinase-like RIO1 PF01163.22 EKX55320.1 - 0.00054 19.6 0.2 0.00077 19.1 0.2 1.2 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 EKX55320.1 - 0.0056 16.3 0.1 0.018 14.6 0.0 1.9 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EKX55320.1 - 0.0066 15.8 0.1 0.0098 15.3 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EKX55320.1 - 0.049 13.1 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL MORN PF02493.20 EKX55321.1 - 1.2e-18 65.8 30.5 0.00012 21.8 1.7 5.9 5 0 0 5 5 5 5 MORN repeat SET PF00856.28 EKX55321.1 - 4.6e-07 30.4 0.4 1.8e-06 28.5 0.0 2.0 2 0 0 2 2 2 1 SET domain Raptor_N PF14538.6 EKX55321.1 - 0.061 13.3 0.0 3.8 7.5 0.0 2.3 1 1 0 2 2 2 0 Raptor N-terminal CASPase like domain MORN_2 PF07661.13 EKX55321.1 - 0.18 12.1 5.0 6.2 7.4 0.1 4.4 5 0 0 5 5 5 0 MORN repeat variant Glyco_transf_41 PF13844.6 EKX55322.1 - 3.3e-61 207.2 0.0 6.8e-36 123.7 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_2 PF07719.17 EKX55322.1 - 3.4e-05 23.6 9.4 0.1 12.8 0.0 5.9 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX55322.1 - 0.00038 20.9 9.3 2 9.0 1.5 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX55322.1 - 0.00038 20.6 2.1 0.0045 17.2 0.3 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EKX55322.1 - 0.0006 19.8 0.1 0.025 14.7 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX55322.1 - 0.0019 18.0 0.2 0.2 11.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EKX55322.1 - 0.0029 17.3 0.2 8.1 6.2 0.0 4.2 4 1 1 5 5 5 1 TPR repeat TPR_14 PF13428.6 EKX55322.1 - 0.0057 17.4 28.9 0.19 12.6 0.7 6.7 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.6 EKX55322.1 - 0.1 12.9 10.3 2.7 8.4 0.0 3.6 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 EKX55322.1 - 0.2 12.1 1.6 23 5.7 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3446 PF11928.8 EKX55322.1 - 0.23 11.8 8.5 0.53 10.6 8.5 1.5 1 0 0 1 1 1 0 Early growth response N-terminal domain TPR_16 PF13432.6 EKX55322.1 - 0.56 10.9 27.8 2.3 9.0 0.1 6.1 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX55322.1 - 2.5 8.1 12.0 2.4 8.1 0.2 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EKX55324.1 - 6.7e-14 50.8 0.9 8.3e-05 22.4 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX55324.1 - 5.1e-08 32.5 0.2 6.2e-06 25.8 0.0 3.4 2 1 2 4 4 4 1 TPR repeat TPR_1 PF00515.28 EKX55324.1 - 7.8e-07 28.7 0.1 0.061 13.2 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX55324.1 - 2.1e-05 25.0 2.2 3.7 8.6 0.0 4.0 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EKX55324.1 - 2.2e-05 24.3 0.0 2.8 8.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX55324.1 - 3e-05 24.5 0.8 1.4 9.6 0.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX55324.1 - 0.0015 18.7 0.6 2.7 8.3 0.0 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX55324.1 - 0.02 15.1 0.8 0.5 10.6 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX55324.1 - 0.032 14.8 0.5 23 5.9 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat HemY_N PF07219.13 EKX55324.1 - 0.076 13.2 0.1 3.8 7.8 0.0 2.8 2 1 1 3 3 3 0 HemY protein N-terminus Pkinase PF00069.25 EKX55326.1 - 1.2e-69 234.6 0.0 1.4e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX55326.1 - 7.6e-49 166.3 0.0 1e-48 165.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EKX55326.1 - 3.5e-06 26.1 0.0 4.9e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EKX55326.1 - 0.00031 20.2 0.0 0.00044 19.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 EKX55326.1 - 0.042 13.4 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 EKX55326.1 - 0.05 13.5 0.1 3.9 7.3 0.1 2.8 1 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EKX55326.1 - 0.067 12.2 0.0 0.096 11.7 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 EKX55326.1 - 0.12 11.3 0.0 1.8 7.5 0.0 2.0 2 0 0 2 2 2 0 Haspin like kinase domain Glycos_transf_2 PF00535.26 EKX55327.1 - 3e-05 23.9 0.0 3.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 EKX55327.1 - 0.0084 15.6 0.0 0.028 13.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 SNF2_N PF00176.23 EKX55328.1 - 3.5e-65 220.0 0.5 5.2e-65 219.5 0.5 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EKX55328.1 - 5e-17 62.3 0.2 1.6e-16 60.6 0.0 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX55328.1 - 8.4e-10 38.9 0.0 3.1e-09 37.1 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EKX55328.1 - 2.2e-05 23.8 1.2 4.1e-05 22.9 0.1 2.0 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 EKX55328.1 - 0.00014 21.7 0.0 0.00035 20.4 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EKX55328.1 - 0.0014 18.3 1.1 0.0029 17.3 0.0 2.2 3 0 0 3 3 3 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 EKX55328.1 - 0.021 14.0 0.1 0.021 14.0 0.1 1.7 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase tRNA_deacylase PF04414.12 EKX55329.1 - 0.011 15.2 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 D-aminoacyl-tRNA deacylase Ephrin_rec_like PF07699.13 EKX55330.1 - 2.5e-10 39.9 13.2 9e-09 35.0 1.6 3.0 1 1 1 2 2 2 2 Putative ephrin-receptor like Laminin_G_3 PF13385.6 EKX55330.1 - 2.1e-08 34.4 0.0 3.3e-07 30.6 0.0 2.2 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4215 PF13948.6 EKX55330.1 - 3.3e-08 33.8 6.3 3.3e-08 33.8 6.3 3.7 5 0 0 5 5 5 1 Domain of unknown function (DUF4215) EGF_3 PF12947.7 EKX55330.1 - 0.0033 17.6 3.5 0.0033 17.6 3.5 2.7 2 0 0 2 2 2 1 EGF domain Sialidase PF02973.16 EKX55330.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Sialidase, N-terminal domain Uso1_p115_C PF04871.13 EKX55331.1 - 0.0025 18.2 12.4 0.0025 18.2 12.4 17.1 8 4 9 18 18 18 2 Uso1 / p115 like vesicle tethering protein, C terminal region 2OG-FeII_Oxy_3 PF13640.6 EKX55332.1 - 3.5e-10 40.6 0.0 4.2e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Oxygenase-NA PF09859.9 EKX55332.1 - 9.4e-06 25.3 0.1 0.00013 21.5 0.1 2.0 1 1 0 1 1 1 1 Oxygenase, catalysing oxidative methylation of damaged DNA 2OG-FeII_Oxy_4 PF13661.6 EKX55332.1 - 9.5e-05 23.0 0.0 0.00012 22.7 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EKX55332.1 - 0.0056 17.1 0.0 0.0073 16.8 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Lipocalin_9 PF17186.4 EKX55336.1 - 0.09 13.1 2.8 1.6 9.0 2.4 2.4 1 1 1 2 2 2 0 Lipocalin-like domain DUF150_C PF17384.2 EKX55336.1 - 0.54 10.4 19.0 13 6.1 2.2 4.5 1 1 3 4 4 4 0 RimP C-terminal SH3 domain RP-C_C PF11800.8 EKX55336.1 - 5 7.2 15.2 34 4.4 15.2 2.0 1 1 0 1 1 1 0 Replication protein C C-terminal region Glyco_tranf_2_3 PF13641.6 EKX55337.1 - 0.017 15.1 0.1 0.025 14.5 0.1 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EKX55337.1 - 0.054 13.0 0.0 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EKX55337.1 - 0.16 11.8 0.2 0.29 10.9 0.0 1.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 HEAT_2 PF13646.6 EKX55341.1 - 7.5e-21 74.3 13.0 2e-09 37.7 0.4 3.0 1 1 1 3 3 3 3 HEAT repeats HEAT PF02985.22 EKX55341.1 - 5.6e-12 44.8 7.2 0.00062 19.8 0.0 4.8 4 0 0 4 4 4 4 HEAT repeat HEAT_EZ PF13513.6 EKX55341.1 - 4.5e-09 36.6 2.9 0.0049 17.4 0.5 3.7 3 0 0 3 3 3 3 HEAT-like repeat RTP1_C1 PF10363.9 EKX55341.1 - 0.013 15.7 0.0 0.048 13.8 0.0 2.0 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 EKX55341.1 - 0.023 14.7 0.9 7.2 6.8 0.0 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 EKX55341.1 - 0.33 11.7 15.4 0.42 11.4 0.1 5.9 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat HAD PF12710.7 EKX55342.1 - 5.1e-22 79.2 0.0 7.2e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EKX55342.1 - 1.5e-20 74.4 0.2 2.5e-20 73.7 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ACT_6 PF13740.6 EKX55342.1 - 3.9e-19 68.4 0.5 7.1e-18 64.4 0.1 2.5 2 0 0 2 2 2 1 ACT domain Hydrolase_3 PF08282.12 EKX55342.1 - 5.1e-15 55.9 0.1 1.9e-12 47.5 0.0 3.1 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EKX55342.1 - 1.5e-06 27.8 0.0 0.014 14.8 0.0 2.2 2 0 0 2 2 2 2 Putative Phosphatase HAD_2 PF13419.6 EKX55342.1 - 7.9e-06 26.1 0.1 0.0002 21.5 0.1 2.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase ACT PF01842.25 EKX55342.1 - 0.00046 19.9 0.2 0.11 12.3 0.0 2.5 2 0 0 2 2 2 2 ACT domain S6PP PF05116.13 EKX55342.1 - 0.015 14.8 0.1 0.084 12.4 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Wbp11 PF09429.10 EKX55343.1 - 1.8e-09 37.9 16.3 1.8e-09 37.9 16.3 2.3 1 1 1 2 2 2 1 WW domain binding protein 11 TRIQK PF15168.6 EKX55343.1 - 1.2 9.1 4.3 2.1 8.3 4.3 1.4 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family K_channel_TID PF07941.11 EKX55343.1 - 3.4 8.2 17.0 0.047 14.1 5.3 2.7 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain WDCP PF15390.6 EKX55343.1 - 8.1 4.7 6.8 10 4.3 6.8 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family His_Phos_1 PF00300.22 EKX55344.1 - 5e-11 42.6 0.0 8e-08 32.2 0.1 3.0 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Ion_trans PF00520.31 EKX55345.1 - 1e-15 57.6 23.4 1.5e-15 57.2 23.4 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX55345.1 - 4.2e-13 49.0 4.4 4.2e-13 49.0 4.4 2.5 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 EKX55345.1 - 0.0034 17.4 0.0 0.017 15.2 0.0 2.1 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain Cyclin_N PF00134.23 EKX55346.1 - 2.2e-05 24.2 0.5 0.0056 16.4 0.3 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 EKX55346.1 - 0.00091 19.2 0.5 0.93 9.6 0.2 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat DTW PF03942.15 EKX55347.1 - 1.1e-31 110.2 0.2 1.4e-31 109.7 0.2 1.2 1 0 0 1 1 1 1 DTW domain UCH PF00443.29 EKX55348.1 - 3.6e-46 157.7 0.0 6.2e-46 157.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EKX55348.1 - 6.5e-19 68.7 0.0 2.9e-17 63.3 0.0 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TPR_1 PF00515.28 EKX55348.1 - 2.4e-10 39.8 0.4 4e-05 23.3 0.4 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat USP7_C2 PF14533.6 EKX55348.1 - 1.6e-09 37.8 0.0 1.2e-08 34.9 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin-specific protease C-terminal TPR_2 PF07719.17 EKX55348.1 - 1.3e-07 31.2 1.6 0.01 15.9 0.3 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX55348.1 - 4.2e-07 30.0 0.8 9.6e-07 28.9 0.8 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX55348.1 - 2.4e-05 24.3 1.7 0.086 12.9 0.4 2.7 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 EKX55348.1 - 0.0048 17.0 0.3 0.026 14.7 0.3 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX55348.1 - 0.014 16.1 0.6 0.044 14.4 0.6 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 EKX55348.1 - 0.014 15.7 1.5 0.048 14.0 1.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EKX55348.1 - 0.017 14.8 0.1 7.7 6.3 0.0 2.5 2 0 0 2 2 2 0 TPR repeat Peptidase_C98 PF15499.6 EKX55348.1 - 0.026 14.0 0.0 7.2 6.0 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase TPR_17 PF13431.6 EKX55348.1 - 0.034 14.5 1.0 0.06 13.7 0.0 2.0 2 0 0 2 2 1 0 Tetratricopeptide repeat CNH PF00780.22 EKX55349.1 - 1.5e-30 106.7 0.0 2.2e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 CNH domain Vps39_2 PF10367.9 EKX55349.1 - 1.3e-27 96.4 0.1 5.7e-27 94.3 0.1 2.2 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 EKX55349.1 - 4.8e-24 84.7 2.2 1.6e-22 79.8 0.0 3.6 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 EKX55349.1 - 2.4e-21 76.1 0.0 2.8e-11 43.5 0.1 3.7 3 0 0 3 3 3 2 Region in Clathrin and VPS TPR_12 PF13424.6 EKX55349.1 - 0.0046 17.2 6.3 1.2 9.5 0.1 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EKX55349.1 - 0.0054 16.9 2.7 1.9 8.9 0.1 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX55349.1 - 0.0076 17.0 8.9 3.2 8.8 0.0 5.9 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 EKX55349.1 - 0.0099 15.9 4.2 4.2 7.7 0.2 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX55349.1 - 0.027 14.3 0.2 3 7.8 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EKX55349.1 - 0.14 12.1 4.0 15 5.7 0.1 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EKX55349.1 - 1 10.0 9.8 24 5.7 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EKX55349.1 - 5 7.4 6.3 4.7 7.5 0.3 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat HSF_DNA-bind PF00447.17 EKX55350.1 - 4.8e-25 88.0 0.1 5.3e-25 87.9 0.1 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding Glyco_transf_34 PF05637.12 EKX55351.1 - 1.8e-10 40.9 0.0 5.2e-08 32.9 0.0 2.6 2 1 0 2 2 2 1 galactosyl transferase GMA12/MNN10 family TPR_20 PF14561.6 EKX55351.1 - 0.022 15.1 0.1 0.046 14.0 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 EKX55351.1 - 0.027 15.0 0.1 0.052 14.1 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Proteasome PF00227.26 EKX55352.1 - 1.3e-51 174.8 0.8 1.7e-51 174.4 0.8 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EKX55352.1 - 6.5e-14 51.3 0.1 1.1e-13 50.5 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Histone PF00125.24 EKX55353.1 - 7.6e-17 61.9 0.0 8.9e-17 61.7 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EKX55353.1 - 0.00037 20.7 0.0 0.00044 20.5 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone MIF PF01187.18 EKX55354.1 - 5.6e-26 91.1 0.0 7.4e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 EKX55354.1 - 0.00029 20.7 0.0 0.21 11.5 0.0 2.3 2 0 0 2 2 2 2 Tautomerase enzyme Tautomerase_2 PF14552.6 EKX55354.1 - 0.063 13.4 0.0 13 5.9 0.0 2.2 2 0 0 2 2 2 0 Tautomerase enzyme PI3K_p85B PF02192.16 EKX55354.1 - 0.22 11.3 0.0 2.2 8.1 0.0 2.0 2 0 0 2 2 2 0 PI3-kinase family, p85-binding domain Pkinase PF00069.25 EKX55355.1 - 6.1e-44 150.4 0.0 9.9e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EKX55355.1 - 8.5e-18 64.6 0.0 1.7e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EKX55355.1 - 0.02 14.2 0.0 0.052 12.8 0.0 1.6 1 1 0 1 1 1 0 Kinase-like AMPK1_CBM PF16561.5 EKX55356.1 - 3.9e-15 55.8 0.0 1e-14 54.5 0.0 1.7 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Synaptonemal_3 PF15191.6 EKX55356.1 - 0.034 13.9 2.0 0.11 12.3 2.0 1.9 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 mTERF PF02536.14 EKX55357.1 - 2.3e-05 23.5 0.0 3.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 mTERF Pox_Ag35 PF03286.14 EKX55357.1 - 0.3 10.8 7.7 2.5 7.9 3.5 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein FAM176 PF14851.6 EKX55357.1 - 1.3 8.7 9.7 4.9 6.8 3.9 2.3 2 0 0 2 2 2 0 FAM176 family RNA_pol_3_Rpc31 PF11705.8 EKX55357.1 - 2.8 8.1 22.5 0.52 10.5 13.0 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DUF1840 PF08895.11 EKX55357.1 - 6.2 7.2 6.3 54 4.2 3.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) DUF2072 PF09845.9 EKX55357.1 - 6.7 7.0 7.9 0.51 10.6 2.8 1.7 2 0 0 2 2 2 0 Zn-ribbon containing protein Myc_N PF01056.18 EKX55357.1 - 9.3 6.0 8.9 3 7.6 1.9 2.2 2 0 0 2 2 2 0 Myc amino-terminal region EF-hand_7 PF13499.6 EKX55358.1 - 3.8e-07 30.5 2.8 2.7e-06 27.7 0.2 3.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 EKX55358.1 - 3.3e-05 23.5 0.4 0.00077 19.2 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EKX55358.1 - 0.00047 19.5 0.1 0.0023 17.3 0.1 2.3 2 0 0 2 2 2 1 EF hand SelB-wing_2 PF09106.11 EKX55358.1 - 0.072 13.3 0.3 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Elongation factor SelB, winged helix EF-hand_8 PF13833.6 EKX55358.1 - 0.098 12.5 0.1 0.34 10.8 0.1 2.0 1 1 0 1 1 1 0 EF-hand domain pair T3SSipB PF16535.5 EKX55358.1 - 1.8 9.1 7.1 0.42 11.1 1.7 2.3 2 0 0 2 2 2 0 Type III cell invasion protein SipB BCIP PF13862.6 EKX55359.1 - 3.4e-42 144.6 0.9 4.5e-42 144.2 0.9 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Rhomboid PF01694.22 EKX55360.1 - 3.7e-16 59.5 4.1 6.6e-16 58.7 4.1 1.5 1 1 0 1 1 1 1 Rhomboid family BRCT_2 PF16589.5 EKX55361.1 - 2.3e-33 114.4 2.3 3.9e-05 24.0 0.0 6.4 6 0 0 6 6 6 6 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EKX55361.1 - 1.3e-31 108.7 4.0 3.2e-09 37.0 0.3 6.7 7 0 0 7 7 7 5 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EKX55361.1 - 5.8e-29 99.8 0.7 1.9e-15 56.6 0.9 4.7 4 0 0 4 4 4 3 twin BRCT domain RTT107_BRCT_5 PF16770.5 EKX55361.1 - 3.8e-14 52.4 0.0 5.7e-07 29.3 0.0 5.0 5 0 0 5 5 5 3 Regulator of Ty1 transposition protein 107 BRCT domain LIG3_BRCT PF16759.5 EKX55361.1 - 4.4e-09 36.5 0.1 1.1 9.6 0.0 5.7 6 0 0 6 6 6 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 EKX55361.1 - 5.9e-07 29.5 0.7 0.003 17.6 0.2 3.8 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain SWIRM-assoc_2 PF16496.5 EKX55361.1 - 8.4 5.1 9.8 1.6 7.5 0.2 3.4 4 0 0 4 4 4 0 SWIRM-associated domain at the N-terminal DUF1525 PF07511.11 EKX55362.1 - 0.034 14.3 1.4 4.2 7.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) T3SS_needle_E PF08988.10 EKX55362.1 - 0.13 12.4 0.4 0.43 10.7 0.4 1.9 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle DEAD PF00270.29 EKX55363.1 - 2.1e-44 151.4 0.0 6.4e-44 149.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX55363.1 - 6.4e-22 78.0 0.0 2.9e-21 75.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EKX55363.1 - 2.6e-09 37.3 0.0 4.4e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EKX55363.1 - 8.7e-07 28.5 0.1 3.2e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit SWI2_SNF2 PF18766.1 EKX55363.1 - 0.0087 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase UTP25 PF06862.12 EKX55363.1 - 0.064 12.0 0.1 0.63 8.7 0.0 2.0 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_11 PF13086.6 EKX55363.1 - 0.088 12.6 0.1 0.088 12.6 0.1 3.0 2 1 1 3 3 3 0 AAA domain WD40 PF00400.32 EKX55364.1 - 2.8e-12 46.9 0.0 0.0061 17.4 0.0 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX55364.1 - 6.3e-05 23.2 0.1 7.2 7.0 0.0 4.4 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain His_Phos_1 PF00300.22 EKX55366.1 - 2.9e-34 118.5 0.0 6e-31 107.6 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) O-FucT PF10250.9 EKX55367.1 - 2.9e-13 50.3 0.0 2.5e-05 24.2 0.0 2.4 1 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Syntaxin-6_N PF09177.11 EKX55368.1 - 0.17 12.5 9.7 0.3 11.7 1.7 3.4 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Csm1_N PF18504.1 EKX55368.1 - 1.2 9.5 7.6 5.9 7.3 0.1 3.2 3 0 0 3 3 3 0 Csm1 N-terminal domain V_ATPase_I PF01496.19 EKX55368.1 - 4.4 5.1 9.4 0.32 8.9 3.4 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family ABM PF03992.16 EKX55371.1 - 6.6e-07 29.4 0.0 8.1e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase SMG1 PF15785.5 EKX55372.1 - 4e-31 108.1 3.7 1.8e-30 105.9 1.0 2.6 2 1 0 2 2 2 1 Serine/threonine-protein kinase smg-1 FAT PF02259.23 EKX55372.1 - 0.0066 15.7 1.3 0.015 14.5 0.3 2.2 2 0 0 2 2 2 1 FAT domain HEAT PF02985.22 EKX55372.1 - 0.02 15.1 3.0 25 5.5 0.3 4.5 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.6 EKX55372.1 - 0.025 15.1 2.2 7.8 7.1 0.0 4.5 3 0 0 3 3 3 0 HEAT-like repeat DUF2524 PF10732.9 EKX55372.1 - 0.1 12.9 2.4 0.15 12.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2524) PI3_PI4_kinase PF00454.27 EKX55373.1 - 5.3e-49 167.3 0.0 7.3e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EKX55373.1 - 8.1e-10 38.4 1.7 8.6e-10 38.3 0.1 1.8 2 0 0 2 2 2 1 FATC domain Metallophos PF00149.28 EKX55374.1 - 9.4e-08 32.8 0.0 1.4e-05 25.7 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase ERp29 PF07749.12 EKX55374.1 - 4.8e-07 30.6 0.1 1.1e-06 29.4 0.1 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Yae1_N PF09811.9 EKX55375.1 - 0.0004 20.0 18.6 0.33 10.7 1.5 5.1 4 1 1 5 5 5 3 Essential protein Yae1, N terminal X PF00739.19 EKX55375.1 - 0.67 10.1 0.0 0.67 10.1 0.0 2.5 2 0 0 2 2 2 0 Trans-activation protein X PP1_inhibitor PF05361.12 EKX55376.1 - 0.0011 19.0 0.0 0.0014 18.7 0.0 1.1 1 0 0 1 1 1 1 PKC-activated protein phosphatase-1 inhibitor SAM_1 PF00536.30 EKX55377.1 - 1.5e-07 31.7 0.1 3e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EKX55377.1 - 2.9e-05 24.1 0.2 7e-05 22.9 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) BES1_N PF05687.13 EKX55377.1 - 0.31 11.4 2.6 0.5 10.7 0.1 2.5 3 0 0 3 3 3 0 BES1/BZR1 plant transcription factor, N-terminal PDZ PF00595.24 EKX55379.1 - 0.0072 16.7 0.4 0.018 15.4 0.4 1.7 1 0 0 1 1 1 1 PDZ domain ATG16 PF08614.11 EKX55379.1 - 0.012 15.9 1.4 0.017 15.3 1.4 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) PDZ_6 PF17820.1 EKX55379.1 - 0.017 14.9 0.6 0.044 13.6 0.6 1.8 1 0 0 1 1 1 0 PDZ domain Zwint PF15556.6 EKX55379.1 - 0.019 14.4 0.4 0.029 13.9 0.4 1.2 1 0 0 1 1 1 0 ZW10 interactor PDZ_2 PF13180.6 EKX55379.1 - 0.03 14.7 0.3 0.03 14.7 0.3 2.2 3 0 0 3 3 3 0 PDZ domain PDZ_4 PF17816.1 EKX55379.1 - 0.031 14.7 0.4 2.5 8.5 0.3 2.6 1 1 1 2 2 2 0 PDZ domain DUF4416 PF14385.6 EKX55379.1 - 0.042 13.8 0.2 0.065 13.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4416) YbaB_DNA_bd PF02575.16 EKX55379.1 - 0.12 12.6 3.8 2.8 8.3 0.1 2.8 2 1 0 2 2 2 0 YbaB/EbfC DNA-binding family Fib_alpha PF08702.10 EKX55379.1 - 2.2 8.5 7.0 1.2 9.3 0.9 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Carboxyl_trans PF01039.22 EKX55380.1 - 8.8e-194 644.7 0.0 1e-193 644.5 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 EKX55380.1 - 0.062 12.8 0.1 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) F5_F8_type_C PF00754.25 EKX55381.1 - 0.034 14.3 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 F5/8 type C domain RelA_SpoT PF04607.17 EKX55382.1 - 3.5e-07 30.5 0.0 0.023 15.0 0.0 2.5 2 0 0 2 2 2 2 Region found in RelA / SpoT proteins F5_F8_type_C PF00754.25 EKX55382.1 - 0.099 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 F5/8 type C domain UPF0242 PF06785.11 EKX55383.1 - 0.0046 17.1 5.1 0.0046 17.1 5.1 2.0 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Macoilin PF09726.9 EKX55383.1 - 4.6 5.7 13.5 6.4 5.2 13.5 1.1 1 0 0 1 1 1 0 Macoilin family TFIIS_M PF07500.14 EKX55384.1 - 3.9e-18 66.0 1.5 3.9e-18 66.0 1.5 2.4 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 EKX55384.1 - 2e-06 27.8 0.0 2.6e-05 24.2 0.0 2.5 3 0 0 3 3 3 1 SPOC domain GTA_holin_3TM PF11351.8 EKX55384.1 - 0.16 12.5 0.7 0.35 11.4 0.7 1.6 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release SH3_1 PF00018.28 EKX55385.1 - 1.3e-12 47.1 0.0 2.5e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EKX55385.1 - 1.5e-10 40.6 0.0 2.8e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EKX55385.1 - 1.1e-09 38.0 0.0 2.8e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain PDZ_6 PF17820.1 EKX55385.1 - 4.5e-05 23.2 0.1 0.0051 16.6 0.0 3.1 3 0 0 3 3 3 1 PDZ domain PDZ PF00595.24 EKX55385.1 - 0.00014 22.1 0.0 0.0023 18.2 0.0 2.7 2 0 0 2 2 2 1 PDZ domain CN_hydrolase PF00795.22 EKX55386.1 - 4e-55 187.0 0.0 5.5e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Kelch_1 PF01344.25 EKX55386.1 - 0.051 13.2 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Kelch motif Kelch_4 PF13418.6 EKX55386.1 - 0.056 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Galactose oxidase, central domain CN_hydrolase PF00795.22 EKX55391.1 - 3.2e-14 52.9 0.0 3.6e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DEAD PF00270.29 EKX55400.1 - 2.2e-45 154.6 0.0 7.4e-45 152.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EKX55400.1 - 8.6e-30 103.3 0.0 6.6e-28 97.3 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain GUCT PF08152.12 EKX55400.1 - 1.4e-14 54.1 0.0 3.3e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 GUCT (NUC152) domain CMS1 PF14617.6 EKX55400.1 - 0.007 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 EKX55400.1 - 0.015 14.5 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF3420 PF11900.8 EKX55400.1 - 0.021 14.9 0.0 0.049 13.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3420) Methyltransf_31 PF13847.6 EKX55401.1 - 3.6e-32 111.3 0.0 5.7e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EKX55401.1 - 1.6e-19 70.4 0.0 3.1e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EKX55401.1 - 1.5e-17 64.0 0.0 2.5e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EKX55401.1 - 1.4e-14 54.1 0.0 2.4e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EKX55401.1 - 6e-12 45.7 0.0 9.4e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EKX55401.1 - 8.1e-12 45.7 0.0 1.3e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EKX55401.1 - 0.00013 21.8 0.1 0.00023 21.0 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 EKX55401.1 - 0.00064 19.2 0.0 0.00094 18.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DOT1 PF08123.13 EKX55401.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_29 PF03141.16 EKX55401.1 - 0.019 13.5 0.0 0.028 13.0 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.15 EKX55401.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase NTP_transf_2 PF01909.23 EKX55402.1 - 7.5e-08 32.6 0.0 1.3e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EKX55402.1 - 0.014 15.5 0.0 0.047 13.8 0.0 1.9 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase DUF1647 PF07801.11 EKX55402.1 - 0.1 12.3 0.0 0.47 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) TPR_14 PF13428.6 EKX55403.1 - 9.3e-16 57.2 13.2 0.033 15.0 0.0 7.8 4 2 4 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.6 EKX55403.1 - 2.2e-15 55.8 16.7 0.0002 21.5 0.2 7.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 EKX55403.1 - 2.3e-14 52.5 25.7 0.037 13.9 0.2 9.0 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 EKX55403.1 - 3.3e-14 51.8 20.0 0.0022 18.0 0.0 8.2 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 EKX55403.1 - 1.1e-12 48.2 10.6 0.0016 18.9 0.3 5.6 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 EKX55403.1 - 6.6e-12 44.6 28.5 0.029 14.5 0.1 8.3 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 EKX55403.1 - 2.8e-11 42.9 11.3 0.2 11.3 0.0 7.4 6 1 2 8 8 8 3 TPR repeat TPR_16 PF13432.6 EKX55403.1 - 1.1e-09 38.8 11.3 0.045 14.4 0.0 6.1 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 EKX55403.1 - 2.6e-08 34.0 21.3 0.023 15.0 0.9 6.5 2 2 5 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 EKX55403.1 - 9.2e-06 25.3 20.1 4.7 7.5 0.1 7.5 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_10 PF13374.6 EKX55403.1 - 2.2e-05 24.2 16.2 6 6.9 0.1 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat Sel1 PF08238.12 EKX55403.1 - 0.00097 19.7 6.5 7.8 7.3 0.1 5.0 5 0 0 5 5 5 1 Sel1 repeat TPR_15 PF13429.6 EKX55403.1 - 0.0027 17.0 1.8 0.61 9.2 0.0 3.5 1 1 1 3 3 3 1 Tetratricopeptide repeat Coatomer_E PF04733.14 EKX55403.1 - 0.0039 16.6 3.5 1.4 8.2 0.1 3.8 2 2 2 4 4 4 1 Coatomer epsilon subunit TAtT PF16811.5 EKX55403.1 - 0.014 14.7 8.7 1.2 8.4 0.1 4.1 4 1 0 4 4 4 0 TRAP transporter T-component UPF0231 PF06062.11 EKX55403.1 - 0.082 13.2 2.5 22 5.3 0.2 3.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0231) RPA_interact_N PF14766.6 EKX55403.1 - 0.16 11.7 1.9 0.38 10.4 1.9 1.6 1 0 0 1 1 1 0 Replication protein A interacting N-terminal TPR_6 PF13174.6 EKX55403.1 - 9.2 7.1 13.7 12 6.8 0.0 6.0 8 0 0 8 8 7 0 Tetratricopeptide repeat FAM165 PF14981.6 EKX55404.1 - 0.2 11.5 0.8 2.3 8.1 0.8 2.9 1 0 0 1 1 1 0 FAM165 family Ank_2 PF12796.7 EKX55405.1 - 6.4e-23 81.1 4.4 1.9e-12 47.6 0.3 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX55405.1 - 4.7e-18 65.3 1.4 4.8e-09 36.6 0.3 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX55405.1 - 1.4e-10 41.1 0.4 1.1e-05 25.7 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EKX55405.1 - 4.3e-10 39.0 0.1 0.0033 17.8 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EKX55405.1 - 4.9e-07 29.9 0.7 0.00067 19.9 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Methyltransf_16 PF10294.9 EKX55406.1 - 2.1e-28 99.2 0.0 2.9e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EKX55406.1 - 5.1e-06 26.4 0.0 7.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EKX55406.1 - 0.0006 19.3 0.0 0.00074 19.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EKX55406.1 - 0.023 14.5 0.2 0.31 10.8 0.2 2.2 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EKX55406.1 - 0.029 13.9 0.1 0.05 13.2 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 EKX55406.1 - 0.041 14.6 0.1 0.093 13.4 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 EKX55406.1 - 0.058 12.9 0.1 0.28 10.7 0.1 1.9 1 1 0 1 1 1 0 Histone methylation protein DOT1 RapH_N PF18801.1 EKX55406.1 - 0.16 12.1 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 response regulator aspartate phosphatase H, N terminal SH3_9 PF14604.6 EKX55407.1 - 6.2e-15 54.8 0.1 1.2e-14 53.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EKX55407.1 - 7.7e-14 51.0 0.0 1.5e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EKX55407.1 - 1.8e-07 30.7 0.0 4.8e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain PFU PF09070.11 EKX55407.1 - 0.066 13.5 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) EF-hand_8 PF13833.6 EKX55407.1 - 0.076 12.9 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair Tryp_alpha_amyl PF00234.22 EKX55407.1 - 0.097 13.1 0.1 0.59 10.6 0.1 2.4 1 0 0 1 1 1 0 Protease inhibitor/seed storage/LTP family RicinB_lectin_2 PF14200.6 EKX55408.1 - 7.4e-26 90.7 6.1 5.2e-12 46.3 0.1 2.7 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 EKX55408.1 - 7.4e-20 71.5 2.3 9.3e-20 71.2 2.3 1.1 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain DUF2511 PF10709.9 EKX55408.1 - 0.035 14.4 0.5 0.12 12.7 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2511) F-box_4 PF15966.5 EKX55408.1 - 0.061 13.2 0.2 2 8.3 0.0 2.2 2 0 0 2 2 2 0 F-box NTP_transf_9 PF04248.12 EKX55408.1 - 0.16 11.9 0.8 16 5.5 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF427) NCA2 PF08637.10 EKX55409.1 - 2.1e-11 43.5 1.7 2.1e-10 40.3 0.9 2.9 2 1 0 2 2 2 1 ATP synthase regulation protein NCA2 DUF2115 PF09888.9 EKX55411.1 - 0.2 12.1 2.8 0.41 11.2 2.8 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) Ank_2 PF12796.7 EKX55412.1 - 8.9e-11 42.2 0.1 2e-09 37.9 0.0 2.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EKX55412.1 - 4.1e-10 40.0 0.8 1.9e-06 28.3 0.2 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX55412.1 - 5.9e-09 35.5 0.1 0.021 15.3 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EKX55412.1 - 3e-08 33.7 0.0 0.016 15.6 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EKX55412.1 - 7.1e-08 32.6 0.0 7.3e-06 26.2 0.1 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Elf1 PF05129.13 EKX55413.1 - 0.00043 20.3 0.5 0.00076 19.5 0.5 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zinc_ribbon_5 PF13719.6 EKX55413.1 - 0.0057 16.4 0.9 0.018 14.8 0.0 2.0 2 0 0 2 2 2 1 zinc-ribbon domain zf-C2HC_2 PF13913.6 EKX55413.1 - 0.0086 16.0 5.4 0.081 12.9 0.4 2.7 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zinc_ribbon_4 PF13717.6 EKX55413.1 - 0.018 14.9 0.2 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-Mss51 PF13824.6 EKX55413.1 - 0.021 14.9 0.2 0.038 14.1 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-CSL PF05207.13 EKX55413.1 - 0.038 13.7 0.3 6.1 6.6 0.1 2.3 2 0 0 2 2 2 0 CSL zinc finger zf-LITAF-like PF10601.9 EKX55413.1 - 0.82 10.0 2.8 32 4.9 0.1 3.0 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain DDE_Tnp_1_7 PF13843.6 EKX55414.1 - 1.4e-30 106.8 0.1 3.8e-30 105.4 0.0 1.6 2 0 0 2 2 2 1 Transposase IS4 Peripla_BP_2 PF01497.18 EKX55415.1 - 0.045 13.3 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein PTS_IIA PF02255.16 EKX55416.1 - 0.27 11.3 4.9 0.48 10.5 0.2 2.3 1 1 1 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit VPS38 PF17649.1 EKX55416.1 - 1 8.2 8.0 0.88 8.4 2.4 2.1 2 0 0 2 2 2 0 Vacuolar protein sorting 38 DUF4200 PF13863.6 EKX55417.1 - 0.0037 17.6 8.5 0.0037 17.6 8.5 4.4 1 1 2 3 3 3 2 Domain of unknown function (DUF4200) UBA_2 PF08587.11 EKX55417.1 - 0.047 13.8 0.5 14 5.9 0.0 2.7 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) DUF4460 PF14687.6 EKX55417.1 - 0.064 13.3 0.6 0.29 11.2 0.6 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) Fib_alpha PF08702.10 EKX55417.1 - 0.59 10.3 16.5 3.8 7.7 4.9 3.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family HALZ PF02183.18 EKX55417.1 - 0.68 10.2 8.5 11 6.3 0.1 4.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper GAS PF13851.6 EKX55417.1 - 1.9 7.8 34.1 0.34 10.2 11.5 3.5 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF724 PF05266.14 EKX55417.1 - 3.5 7.4 29.2 0.71 9.7 5.1 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF724) UPF0242 PF06785.11 EKX55417.1 - 6.8 6.7 36.6 1.2 9.2 10.2 3.6 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Spc7 PF08317.11 EKX55417.1 - 8.4 5.2 36.1 1.4 7.7 12.9 3.4 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF4407 PF14362.6 EKX55417.1 - 9.8 5.4 23.4 6.2 6.1 7.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TPR_2 PF07719.17 EKX55419.1 - 0.00052 19.9 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX55419.1 - 0.0017 18.1 0.5 0.0072 16.1 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat SPRY PF00622.28 EKX55419.1 - 0.019 15.1 0.1 0.044 13.9 0.1 1.6 2 0 0 2 2 2 0 SPRY domain TPR_12 PF13424.6 EKX55419.1 - 0.12 12.7 0.0 0.73 10.2 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Mpv17_PMP22 PF04117.12 EKX55420.1 - 2.7e-09 37.1 1.4 3.2e-09 36.9 0.3 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family DUF1952 PF09189.10 EKX55420.1 - 0.16 11.8 0.1 0.39 10.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1952) SARAF PF06682.12 EKX55421.1 - 0.0014 18.4 0.2 0.0075 16.0 0.0 2.0 2 0 0 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis DUF3671 PF12420.8 EKX55421.1 - 0.0022 18.1 8.5 2.3 8.3 0.1 3.4 3 0 0 3 3 3 2 Protein of unknown function DUF2615 PF11027.8 EKX55421.1 - 0.0033 17.5 1.4 0.0033 17.5 1.4 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2615) EphA2_TM PF14575.6 EKX55421.1 - 0.044 14.7 2.4 0.49 11.3 0.0 2.9 3 0 0 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4064 PF13273.6 EKX55421.1 - 0.11 12.8 5.6 0.1 12.9 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Zn_peptidase PF04228.13 EKX55421.1 - 0.69 9.3 2.2 0.45 9.9 0.4 1.5 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase TMEM154 PF15102.6 EKX55421.1 - 0.73 9.7 13.8 3.1 7.7 0.8 2.8 2 0 0 2 2 2 0 TMEM154 protein family Secretin_N_2 PF07655.13 EKX55421.1 - 1.2 9.8 30.3 0.8 10.3 5.1 3.0 3 0 0 3 3 3 0 Secretin N-terminal domain UPF0239 PF06783.11 EKX55421.1 - 1.6 8.9 4.4 5.7 7.2 0.4 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0239) FAM176 PF14851.6 EKX55421.1 - 2.1 8.0 10.9 0.44 10.2 0.0 3.2 3 1 0 3 3 3 0 FAM176 family EpsG PF14897.6 EKX55421.1 - 3.8 6.7 6.5 0.82 8.9 0.2 2.3 2 1 0 2 2 2 0 EpsG family O-ag_pol_Wzy PF14296.6 EKX55421.1 - 6.3 5.3 17.4 3.8 6.1 5.2 2.2 2 0 0 2 2 2 0 O-antigen polysaccharide polymerase Wzy DUF4446 PF14584.6 EKX55421.1 - 9.5 6.2 9.3 1.4 8.9 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) PDZ_6 PF17820.1 EKX55422.1 - 4.4e-10 39.2 0.1 6.2e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EKX55422.1 - 5.2e-06 26.7 0.0 6.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EKX55422.1 - 5.4e-06 26.7 0.0 6.5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 EKX55422.1 - 0.00019 21.3 0.0 0.00026 20.9 0.0 1.2 1 0 0 1 1 1 1 Tricorn protease PDZ domain Sulfotransfer_3 PF13469.6 EKX55423.1 - 1.1e-10 42.3 0.1 2.6e-05 24.7 0.0 2.1 2 0 0 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 EKX55423.1 - 2.3e-09 37.1 0.0 0.00034 20.2 0.0 2.1 1 1 1 2 2 2 2 Sulfotransferase domain DUF4380 PF14315.6 EKX55423.1 - 0.03 13.3 0.0 0.039 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4380) Zeta_toxin PF06414.12 EKX55424.1 - 0.0024 17.2 2.4 0.0034 16.7 2.4 1.1 1 0 0 1 1 1 1 Zeta toxin DNA_ligase_A_M PF01068.21 EKX55424.1 - 0.0081 15.8 0.5 0.012 15.3 0.5 1.2 1 0 0 1 1 1 1 ATP dependent DNA ligase domain APG6_N PF17675.1 EKX55424.1 - 0.15 12.6 12.9 0.29 11.6 12.9 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region LRR_8 PF13855.6 EKX55425.1 - 7.8e-11 41.6 10.8 1.3e-06 28.1 2.9 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EKX55425.1 - 1.8e-06 28.2 10.1 0.0037 17.6 0.3 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EKX55425.1 - 0.0013 19.0 12.2 0.69 10.7 2.3 4.3 3 2 0 3 3 3 3 Leucine Rich Repeat Importin_rep_2 PF18786.1 EKX55425.1 - 0.15 12.0 3.1 8.3 6.4 0.1 3.0 2 1 1 3 3 3 0 Importin 13 repeat LRR_6 PF13516.6 EKX55425.1 - 0.31 11.2 6.0 15 5.9 0.1 3.5 3 1 0 3 3 3 0 Leucine Rich repeat CDP-OH_P_transf PF01066.21 EKX55426.1 - 3.8e-10 40.4 0.3 3.8e-10 40.4 0.3 1.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase RWP-RK PF02042.15 EKX55427.1 - 6.4e-18 64.5 0.0 1.1e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain Bee_toxin PF17454.2 EKX55427.1 - 0.12 12.5 0.5 0.21 11.7 0.5 1.4 1 0 0 1 1 1 0 Honey bee toxin Cnn_1N PF07989.11 EKX55428.1 - 0.38 11.0 4.4 0.79 9.9 1.2 2.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 HALZ PF02183.18 EKX55428.1 - 0.56 10.5 6.8 0.11 12.7 2.4 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper Spc24 PF08286.11 EKX55428.1 - 1.9 8.8 5.1 0.89 9.8 1.8 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TPR_MLP1_2 PF07926.12 EKX55428.1 - 2 8.5 14.3 0.28 11.2 8.4 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein HAUS6_N PF14661.6 EKX55428.1 - 4 7.0 7.6 0.5 9.9 3.0 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus PUB PF09409.10 EKX55430.1 - 1.5e-11 44.0 0.0 3.4e-11 42.9 0.0 1.6 2 0 0 2 2 2 1 PUB domain WLM PF08325.10 EKX55430.1 - 1.2e-06 28.7 0.1 2.7e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 WLM domain DnaI_N PF07319.11 EKX55431.1 - 0.12 13.1 0.4 10 6.9 0.0 2.2 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus Trp_dioxygenase PF03301.13 EKX55432.1 - 3.7e-85 286.3 4.4 4.5e-85 286.0 4.4 1.1 1 0 0 1 1 1 1 Tryptophan 2,3-dioxygenase Mg_trans_NIPA PF05653.14 EKX55433.1 - 2.8e-17 62.8 20.6 1.9e-16 60.1 20.5 2.2 2 1 0 2 2 2 1 Magnesium transporter NIPA EamA PF00892.20 EKX55433.1 - 2.2e-05 24.7 4.0 2.2e-05 24.7 4.0 3.3 2 1 0 3 3 2 1 EamA-like transporter family Sugar_transport PF06800.12 EKX55433.1 - 0.00038 19.9 9.7 0.00074 18.9 0.8 2.7 3 0 0 3 3 3 2 Sugar transport protein UPF0242 PF06785.11 EKX55433.1 - 0.0091 16.1 0.3 0.37 10.9 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus YiaAB PF05360.14 EKX55433.1 - 0.028 14.6 2.6 0.041 14.1 0.7 2.4 2 0 0 2 2 2 0 yiaA/B two helix domain G0-G1_switch_2 PF15103.6 EKX55433.1 - 0.029 14.8 0.1 14 6.2 0.0 2.8 2 0 0 2 2 2 0 G0/G1 switch protein 2 DUF4620 PF15399.6 EKX55433.1 - 0.037 14.4 0.0 7 7.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4620) SLATT_5 PF18160.1 EKX55433.1 - 0.045 13.1 0.7 2.9 7.2 0.0 2.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF3671 PF12420.8 EKX55433.1 - 0.088 12.9 3.3 2.2 8.4 0.6 3.0 2 1 1 3 3 3 0 Protein of unknown function tRNA_anti-like PF12869.7 EKX55433.1 - 0.094 12.3 3.4 3 7.4 0.0 2.9 3 0 0 3 3 2 0 tRNA_anti-like Neurensin PF14927.6 EKX55433.1 - 0.5 10.1 1.9 37 4.0 0.0 3.2 4 0 0 4 4 4 0 Neurensin Saf_2TM PF18303.1 EKX55433.1 - 1.2 8.7 4.4 4.9 6.7 0.0 3.1 2 1 0 2 2 2 0 SAVED-fused 2TM effector domain OAD_gamma PF04277.13 EKX55433.1 - 2.6 8.7 5.4 49 4.6 0.0 3.8 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain LapA_dom PF06305.11 EKX55433.1 - 3.5 7.5 8.6 19 5.1 0.0 3.8 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain HATPase_c PF02518.26 EKX55434.1 - 1.6e-26 93.0 0.0 2.3e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EKX55434.1 - 7e-16 58.0 0.4 1.2e-15 57.2 0.4 1.4 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.6 EKX55434.1 - 0.032 14.2 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Response_reg PF00072.24 EKX55435.1 - 2.6e-22 79.1 0.1 3.1e-22 78.9 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Ldh_1_N PF00056.23 EKX55435.1 - 0.034 14.2 0.1 0.053 13.6 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain EF-hand_6 PF13405.6 EKX55436.1 - 1.6e-14 52.5 1.7 0.00065 19.4 0.0 5.2 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.6 EKX55436.1 - 4.2e-14 52.7 1.1 2.9e-05 24.4 0.0 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EKX55436.1 - 1.9e-13 48.9 4.5 0.0015 17.9 0.1 5.2 5 0 0 5 5 5 4 EF hand EF-hand_5 PF13202.6 EKX55436.1 - 1.1e-12 46.9 5.2 0.049 13.1 0.0 5.4 5 0 0 5 5 5 5 EF hand LysM PF01476.20 EKX55436.1 - 2.7e-11 43.4 0.1 1.6e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 LysM domain SPARC_Ca_bdg PF10591.9 EKX55436.1 - 6e-05 23.3 0.0 0.15 12.4 0.0 2.8 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 EKX55436.1 - 0.00058 19.7 6.9 4.3 7.3 0.0 5.0 4 1 1 5 5 5 2 EF-hand domain pair Dockerin_1 PF00404.18 EKX55436.1 - 0.0014 18.8 0.9 3.1 8.1 0.0 3.3 2 1 0 2 2 2 2 Dockerin type I domain WD40 PF00400.32 EKX55437.1 - 3.9e-44 147.7 18.5 1.7e-07 31.8 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EKX55437.1 - 3.4e-12 46.5 0.1 0.082 13.2 0.1 5.1 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EKX55437.1 - 3.7e-05 22.8 0.0 5.1 6.0 0.0 3.8 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EKX55437.1 - 0.0047 16.8 0.0 0.028 14.4 0.0 2.3 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat eIF2A PF08662.11 EKX55437.1 - 0.011 15.6 0.0 20 5.0 0.0 3.7 1 1 4 5 5 5 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EKX55437.1 - 0.033 12.8 0.9 0.26 9.9 0.0 2.7 2 2 2 4 4 4 0 Nucleoporin Nup120/160 WD40_like PF17005.5 EKX55437.1 - 0.1 11.9 0.0 1.7 7.9 0.0 2.7 4 0 0 4 4 4 0 WD40-like domain C2 PF00168.30 EKX55438.1 - 1e-22 80.3 0.0 1.1e-22 80.2 0.0 1.0 1 0 0 1 1 1 1 C2 domain Hydrolase PF00702.26 EKX55439.1 - 0.00015 22.1 0.0 0.00069 20.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EKX55439.1 - 0.00023 21.6 0.0 0.062 13.7 0.0 2.3 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EKX55439.1 - 0.014 15.5 0.0 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase BSP_II PF05432.11 EKX55441.1 - 1.4 8.5 7.1 1.9 8.1 7.1 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TLD PF07534.16 EKX55442.1 - 6.1e-12 45.9 0.0 1.5e-11 44.7 0.0 1.6 1 1 1 2 2 2 1 TLD WW PF00397.26 EKX55442.1 - 1.5e-06 28.2 0.9 1.5e-06 28.2 0.9 2.1 2 0 0 2 2 2 1 WW domain Glyco_hyd_101C PF17451.2 EKX55442.1 - 0.049 13.9 0.4 0.11 12.8 0.2 1.6 2 0 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain SET PF00856.28 EKX55443.1 - 7.3e-14 52.5 0.0 8.9e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 SET domain Pet127 PF08634.10 EKX55444.1 - 1.2e-79 267.6 0.3 1.7e-79 267.1 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 adh_short_C2 PF13561.6 EKX55445.1 - 2.8e-65 220.1 0.8 3.5e-65 219.9 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EKX55445.1 - 8.2e-53 178.8 0.7 9.6e-53 178.5 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EKX55445.1 - 7.6e-15 55.3 0.2 1.1e-14 54.8 0.2 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EKX55445.1 - 1.7e-05 24.3 0.0 2.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF1847 PF08901.11 EKX55445.1 - 0.024 14.3 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1847) NAD_binding_10 PF13460.6 EKX55445.1 - 0.12 12.3 0.1 0.17 11.8 0.1 1.2 1 0 0 1 1 1 0 NAD(P)H-binding SCO1-SenC PF02630.14 EKX55445.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 SCO1/SenC Myb_DNA-binding PF00249.31 EKX55446.1 - 6.8e-22 77.4 2.4 2.8e-10 40.2 0.0 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX55446.1 - 2.3e-09 37.3 15.0 2.5e-05 24.4 0.2 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain RWD PF05773.22 EKX55446.1 - 2.5e-05 24.5 0.0 2.5e-05 24.5 0.0 2.7 2 1 0 2 2 2 1 RWD domain DUF4637 PF15470.6 EKX55446.1 - 0.00053 19.8 3.8 0.00053 19.8 3.8 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4637) TFIIA PF03153.13 EKX55446.1 - 0.0022 18.1 22.8 0.0029 17.7 22.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit HAD_2 PF13419.6 EKX55446.1 - 2.7 8.0 6.5 2.4 8.2 5.0 1.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase PPDK_N PF01326.19 EKX55447.1 - 4.9e-24 85.2 0.0 1.2e-15 57.6 0.0 3.6 1 1 1 2 2 2 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain Rad17 PF03215.15 EKX55449.1 - 3.6e-14 53.1 0.0 8.3e-14 51.9 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 EKX55449.1 - 0.0001 22.7 0.0 0.00036 21.0 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EKX55449.1 - 0.00017 21.5 0.0 0.00038 20.4 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 EKX55449.1 - 0.00035 21.1 0.0 0.00098 19.6 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 EKX55449.1 - 0.00067 19.9 0.1 0.002 18.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.6 EKX55449.1 - 0.00091 19.3 0.0 0.0019 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EKX55449.1 - 0.001 19.5 0.1 0.0028 18.1 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_assoc_2 PF16193.5 EKX55449.1 - 0.0047 17.2 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_33 PF13671.6 EKX55449.1 - 0.0076 16.4 0.0 0.019 15.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EKX55449.1 - 0.017 15.1 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 EKX55449.1 - 0.028 13.6 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Cytidylate_kin PF02224.18 EKX55449.1 - 0.034 13.9 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase ATPase_2 PF01637.18 EKX55449.1 - 0.043 13.7 0.0 0.25 11.2 0.0 2.1 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea TsaE PF02367.17 EKX55449.1 - 0.046 13.7 0.1 0.16 12.0 0.0 1.7 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EKX55449.1 - 0.065 13.5 0.0 0.15 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EKX55449.1 - 0.07 13.5 0.2 0.25 11.8 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Adeno_IVa2 PF02456.15 EKX55449.1 - 0.15 10.8 0.0 0.3 9.8 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein AP2 PF00847.20 EKX55450.1 - 1.8e-06 28.1 12.0 0.002 18.3 1.4 3.5 3 0 0 3 3 3 3 AP2 domain Ion_trans PF00520.31 EKX55451.1 - 4e-13 49.2 15.8 7.3e-13 48.3 15.8 1.4 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EKX55451.1 - 5.6e-09 35.9 7.0 5.6e-09 35.9 7.0 2.1 2 1 1 3 3 3 1 Ion channel cNMP_binding PF00027.29 EKX55451.1 - 2.4e-08 34.0 0.0 4.9e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain CLZ PF16526.5 EKX55451.1 - 0.065 13.6 1.0 0.18 12.2 1.0 1.8 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DASH_Dad2 PF08654.10 EKX55451.1 - 0.079 13.4 0.1 0.22 12.0 0.1 1.7 1 0 0 1 1 1 0 DASH complex subunit Dad2 UPF0242 PF06785.11 EKX55451.1 - 0.088 12.9 1.1 0.21 11.7 1.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PI3K_P85_iSH2 PF16454.5 EKX55451.1 - 0.097 12.3 5.1 0.15 11.7 3.6 2.0 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF16 PF01519.16 EKX55451.1 - 0.26 11.8 2.2 0.77 10.3 2.2 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF16 Prefoldin PF02996.17 EKX55451.1 - 0.26 11.2 2.8 0.57 10.1 2.4 1.8 2 0 0 2 2 2 0 Prefoldin subunit L27_1 PF09058.10 EKX55452.1 - 0.12 12.4 2.0 0.22 11.5 2.0 1.5 1 0 0 1 1 1 0 L27_1 Myb_DNA-binding PF00249.31 EKX55453.1 - 4e-32 110.1 0.1 6.1e-18 64.7 0.0 2.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EKX55453.1 - 2.9e-27 94.7 0.1 2.3e-15 56.6 0.0 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EKX55453.1 - 3.5e-08 33.2 0.1 0.00089 19.1 0.0 2.0 2 0 0 2 2 2 2 Myb DNA-binding like Myb_DNA-bind_2 PF08914.11 EKX55453.1 - 0.00092 19.3 1.2 1.9 8.8 0.1 3.2 2 2 0 2 2 2 2 Rap1 Myb domain SLIDE PF09111.10 EKX55453.1 - 0.02 14.9 0.0 1.8 8.6 0.0 2.3 1 1 1 2 2 2 0 SLIDE Myb_DNA-bind_4 PF13837.6 EKX55453.1 - 0.076 13.4 1.3 1.4 9.4 0.1 2.6 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain SWIRM-assoc_2 PF16496.5 EKX55454.1 - 6.1e-35 120.9 13.5 6.1e-35 120.9 13.5 2.1 2 0 0 2 2 2 1 SWIRM-associated domain at the N-terminal Myb_DNA-binding PF00249.31 EKX55454.1 - 8.8e-20 70.6 0.9 2e-09 37.5 0.4 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain SWIRM PF04433.17 EKX55454.1 - 3.2e-12 46.6 0.0 3.1e-07 30.6 0.0 3.0 2 0 0 2 2 2 2 SWIRM domain Myb_DNA-bind_6 PF13921.6 EKX55454.1 - 1.6e-11 44.3 1.1 0.00016 21.8 0.6 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Tudor_4 PF18358.1 EKX55454.1 - 6.7e-06 25.6 0.5 1.6e-05 24.4 0.5 1.6 1 0 0 1 1 1 1 Histone methyltransferase Tudor domain Agenet PF05641.12 EKX55454.1 - 0.00024 21.5 0.3 0.00085 19.7 0.3 2.1 1 0 0 1 1 1 1 Agenet domain SWIRM-assoc_1 PF16495.5 EKX55454.1 - 0.00088 19.2 3.6 0.00088 19.2 3.6 2.5 2 0 0 2 2 2 1 SWIRM-associated region 1 Tudor-knot PF11717.8 EKX55454.1 - 0.0024 17.7 1.4 0.73 9.8 0.5 2.8 2 0 0 2 2 2 2 RNA binding activity-knot of a chromodomain Protocadherin PF08374.11 EKX55454.1 - 0.26 11.2 2.9 0.66 9.9 2.9 1.7 1 0 0 1 1 1 0 Protocadherin MADF_DNA_bdg PF10545.9 EKX55454.1 - 1.7 9.0 7.5 3.2 8.1 1.5 3.4 4 0 0 4 4 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Cnn_1N PF07989.11 EKX55454.1 - 6.7 6.9 9.2 2.3 8.5 3.9 2.8 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Sec1 PF00995.23 EKX55455.1 - 6.3e-94 316.3 14.0 9.5e-93 312.4 14.0 2.3 1 1 0 1 1 1 1 Sec1 family KptA_kDCL PF18176.1 EKX55455.1 - 0.044 13.7 0.1 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 KptA in kinetoplastid DICER domain DUF2853 PF11015.8 EKX55455.1 - 0.056 14.1 0.1 3.1 8.5 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2853) DUF1726 PF08351.11 EKX55455.1 - 0.1 12.5 0.1 13 5.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1726) Baculo_LEF5_C PF11792.8 EKX55455.1 - 0.14 11.8 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain DUF4442 PF14539.6 EKX55456.1 - 1.7e-32 112.3 0.0 2.1e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) Trefoil PF00088.18 EKX55457.1 - 8.8e-07 28.7 4.6 8.8e-07 28.7 4.6 4.5 4 0 0 4 4 4 1 Trefoil (P-type) domain LysM PF01476.20 EKX55457.1 - 4.1e-06 26.8 0.0 2.5e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 LysM domain SUKH_5 PF14567.6 EKX55458.1 - 0.062 13.0 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall Peptidase_M50B PF13398.6 EKX55458.1 - 0.08 12.6 4.6 0.22 11.2 4.6 1.7 1 0 0 1 1 1 0 Peptidase M50B-like CCT_2 PF09425.10 EKX55458.1 - 2 8.4 5.0 7 6.6 5.0 2.0 1 0 0 1 1 1 0 Divergent CCT motif DUF2431 PF10354.9 EKX55459.1 - 1.5e-34 119.7 0.0 1.9e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) CCT_2 PF09425.10 EKX55461.1 - 2.1 8.3 5.0 7.1 6.6 5.0 2.0 1 0 0 1 1 1 0 Divergent CCT motif Kelch_1 PF01344.25 EKX55462.1 - 1.1e-07 31.3 0.1 3e-06 26.7 0.0 2.4 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.6 EKX55462.1 - 0.0017 18.4 0.0 0.0033 17.4 0.0 1.5 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_6 PF13964.6 EKX55462.1 - 0.0021 18.3 0.0 0.0048 17.1 0.0 1.6 1 0 0 1 1 1 1 Kelch motif Kelch_3 PF13415.6 EKX55462.1 - 0.016 15.5 0.2 0.27 11.6 0.0 2.4 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_2 PF07646.15 EKX55462.1 - 0.11 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Kelch motif Kelch_1 PF01344.25 EKX55463.1 - 1.4e-38 130.3 1.3 1.8e-13 49.9 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 EKX55463.1 - 2.6e-24 84.7 0.2 4.8e-09 36.2 0.0 4.9 1 1 4 5 5 5 4 Kelch motif Kelch_4 PF13418.6 EKX55463.1 - 4.2e-15 55.5 0.0 6.6e-05 22.8 0.0 3.4 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_2 PF07646.15 EKX55463.1 - 1.4e-14 53.4 0.3 7.8e-05 22.5 0.0 4.2 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 EKX55463.1 - 1.1e-09 38.0 0.0 0.063 13.3 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 EKX55463.1 - 3e-09 36.9 0.1 0.24 11.7 0.0 4.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Pyr_redox_2 PF07992.14 EKX55464.1 - 1e-65 221.9 0.7 4.3e-65 219.8 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EKX55464.1 - 6.1e-31 106.9 0.2 1.1e-30 106.1 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EKX55464.1 - 4.3e-19 68.8 0.9 1.2e-17 64.2 0.0 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EKX55464.1 - 6.9e-17 61.7 1.0 1.1e-15 57.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EKX55464.1 - 0.00061 19.0 0.0 0.022 13.9 0.0 2.1 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EKX55464.1 - 0.0013 17.5 0.4 1.3 7.7 0.0 2.5 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_7 PF13241.6 EKX55464.1 - 0.0054 17.1 0.0 0.25 11.8 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 EKX55464.1 - 0.0071 16.2 0.4 0.87 9.4 0.0 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 EKX55464.1 - 0.0077 15.6 0.2 0.013 14.8 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EKX55464.1 - 0.034 13.7 3.9 18 4.8 0.1 3.8 4 0 0 4 4 4 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EKX55464.1 - 0.039 13.1 3.1 1.5 7.8 1.8 2.5 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.21 EKX55464.1 - 0.055 12.8 0.1 5.5 6.2 0.6 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EKX55464.1 - 0.066 12.3 3.0 0.17 10.9 1.7 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EKX55464.1 - 2.7 8.3 7.3 0.18 12.0 1.4 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Abhydrolase_1 PF00561.20 EKX55465.1 - 3.1e-14 53.2 0.2 3.6e-12 46.5 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EKX55465.1 - 3.3e-09 37.7 0.0 4.3e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EKX55465.1 - 7.2e-08 32.0 0.0 1.1e-07 31.4 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EKX55465.1 - 7.8e-06 25.0 0.1 1.2e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme PGAP1 PF07819.13 EKX55465.1 - 1.6e-05 24.8 0.0 2.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.20 EKX55465.1 - 2.7e-05 24.0 0.0 3.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 EKX55465.1 - 0.00016 21.8 0.0 0.00022 21.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Ndr PF03096.14 EKX55465.1 - 0.00019 20.2 0.0 0.00023 20.0 0.0 1.1 1 0 0 1 1 1 1 Ndr family Chlorophyllase PF07224.11 EKX55465.1 - 0.0002 20.5 0.1 0.00033 19.8 0.1 1.3 1 0 0 1 1 1 1 Chlorophyllase DUF676 PF05057.14 EKX55465.1 - 0.00032 20.3 0.1 0.00077 19.0 0.1 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) DUF2048 PF09752.9 EKX55465.1 - 0.0052 15.9 0.0 0.0076 15.4 0.0 1.2 1 0 0 1 1 1 1 Abhydrolase domain containing 18 Abhydrolase_5 PF12695.7 EKX55465.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 EKX55465.1 - 0.014 14.9 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 EKX55465.1 - 0.03 14.1 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase BAAT_C PF08840.11 EKX55465.1 - 0.042 13.8 0.2 0.07 13.0 0.2 1.6 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 EKX55465.1 - 0.1 12.4 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase_phd PF10503.9 EKX55465.1 - 0.12 11.9 0.2 0.16 11.4 0.2 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase PDZ_2 PF13180.6 EKX55466.1 - 0.027 14.8 0.4 0.077 13.3 0.4 1.8 1 0 0 1 1 1 0 PDZ domain DUF4776 PF16003.5 EKX55466.1 - 0.08 11.9 9.6 0.11 11.5 9.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) UME PF08064.13 EKX55466.1 - 0.21 11.5 2.0 2.2 8.2 0.1 3.0 3 1 1 4 4 4 0 UME (NUC010) domain VGPC1_C PF16799.5 EKX55466.1 - 0.22 11.5 0.1 0.22 11.5 0.1 2.8 3 1 1 4 4 4 0 C-terminal membrane-localisation domain of ion-channel, VCN1 Hrs_helical PF12210.8 EKX55466.1 - 0.61 10.7 13.5 0.84 10.2 5.7 3.0 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF5354 PF17305.2 EKX55466.1 - 2 8.6 5.5 2.2 8.5 2.0 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5354) AATF-Che1 PF13339.6 EKX55466.1 - 2.1 9.0 15.2 7.7 7.2 13.2 2.5 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor PEP-utilisers_N PF05524.13 EKX55466.1 - 2.1 8.5 5.1 1.4 9.1 2.3 2.2 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Rap1-DNA-bind PF09197.10 EKX55467.1 - 0.0029 18.2 0.0 0.0047 17.5 0.0 1.4 1 0 0 1 1 1 1 Rap1, DNA-binding Lectin_legB PF00139.19 EKX55468.1 - 1.1e-12 48.0 0.0 1.2e-07 31.6 0.0 2.1 2 0 0 2 2 2 2 Legume lectin domain Bact_lectin PF18483.1 EKX55468.1 - 8.8e-12 45.5 0.0 2.1e-11 44.2 0.0 1.5 1 1 0 1 1 1 1 Bacterial lectin EGF_2 PF07974.13 EKX55468.1 - 0.0049 17.2 10.9 0.012 16.0 10.9 1.7 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.7 EKX55468.1 - 0.014 16.0 5.6 0.037 14.7 5.6 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF EGF PF00008.27 EKX55468.1 - 0.036 14.4 7.0 0.08 13.3 7.0 1.6 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 EKX55468.1 - 0.1 12.7 10.4 0.22 11.6 10.4 1.6 1 0 0 1 1 1 0 Tenascin EGF domain EB PF01683.18 EKX55468.1 - 2.1 8.7 6.2 5.7 7.3 6.2 1.7 1 0 0 1 1 1 0 EB module DUF2408 PF10303.9 EKX55469.1 - 1.9 9.0 10.8 5.5 7.6 6.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) FH2 PF02181.23 EKX55469.1 - 2.6 7.1 12.3 9 5.3 0.1 2.4 2 0 0 2 2 2 0 Formin Homology 2 Domain CREPT PF16566.5 EKX55469.1 - 4.8 7.3 10.7 5.7 7.1 4.7 3.3 2 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour SpoU_methylase PF00588.19 EKX55470.1 - 4.9e-13 49.5 0.0 7.1e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family Usp PF00582.26 EKX55471.1 - 4e-15 56.6 0.0 1e-12 48.8 0.0 2.5 2 1 0 2 2 2 2 Universal stress protein family Peptidase_S11 PF00768.20 EKX55472.1 - 0.067 12.6 0.5 0.12 11.8 0.5 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase PPR_3 PF13812.6 EKX55473.1 - 6.9e-23 80.5 0.1 4.5e-09 36.3 0.0 5.7 4 1 1 5 5 5 5 Pentatricopeptide repeat domain PPR_2 PF13041.6 EKX55473.1 - 7.2e-22 77.3 3.6 0.00093 19.3 0.0 7.4 7 1 0 7 7 7 5 PPR repeat family PPR_1 PF12854.7 EKX55473.1 - 4.5e-11 42.3 3.3 0.21 11.3 0.0 7.6 8 0 0 8 8 8 3 PPR repeat PPR_long PF17177.4 EKX55473.1 - 6.2e-08 32.3 0.2 0.00074 18.9 0.3 3.5 1 1 3 4 4 4 3 Pentacotripeptide-repeat region of PRORP SAM_2 PF07647.17 EKX55473.1 - 0.00023 21.2 0.0 0.00065 19.8 0.0 1.8 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EKX55473.1 - 0.0038 17.6 0.0 0.013 15.9 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PPR PF01535.20 EKX55473.1 - 0.012 15.8 13.9 7.9 7.0 0.0 7.4 8 0 0 8 8 8 0 PPR repeat Chorion_2 PF03964.15 EKX55473.1 - 0.079 13.8 1.5 0.46 11.4 1.5 2.4 1 0 0 1 1 1 0 Chorion family 2 DUF4586 PF15239.6 EKX55474.1 - 9e-25 88.5 26.0 3.5e-24 86.5 26.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4586) ComJ PF11033.8 EKX55476.1 - 0.072 12.8 1.2 0.095 12.4 1.2 1.2 1 0 0 1 1 1 0 Competence protein J (ComJ) IMCp PF12314.8 EKX55476.1 - 0.94 9.8 13.9 1.5 9.1 5.8 2.1 1 1 1 2 2 2 0 Inner membrane complex protein GlutR_dimer PF00745.20 EKX55477.1 - 0.026 14.9 0.0 0.071 13.6 0.0 1.6 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Acetyltransf_1 PF00583.25 EKX55478.1 - 1.2e-13 51.3 0.0 1.9e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EKX55478.1 - 8.8e-13 48.3 0.1 1.5e-12 47.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EKX55478.1 - 3e-11 43.6 0.0 5.7e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EKX55478.1 - 8.9e-09 35.2 0.0 1.9e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EKX55478.1 - 1.2e-05 25.5 0.0 2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EKX55478.1 - 0.00013 22.6 0.0 0.00022 21.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EKX55478.1 - 0.0013 18.8 0.0 0.0026 17.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EKX55478.1 - 0.0018 18.4 0.0 0.0032 17.6 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 EKX55478.1 - 0.0087 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 EKX55478.1 - 0.02 14.6 0.2 0.11 12.2 0.0 2.2 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_13 PF13880.6 EKX55478.1 - 0.023 14.7 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_15 PF17013.5 EKX55478.1 - 0.091 12.2 0.3 0.2 11.1 0.3 1.6 1 1 0 1 1 1 0 Putative acetyl-transferase DSPn PF14671.6 EKX55481.1 - 2.4e-30 105.8 0.0 5.3e-29 101.5 0.0 2.3 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EKX55481.1 - 3.3e-12 46.4 0.1 9e-12 45.0 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EKX55481.1 - 0.00014 21.5 0.0 0.00022 20.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EKX55481.1 - 0.0017 18.5 0.0 0.0028 17.8 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EKX55481.1 - 0.012 15.6 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF2115 PF09888.9 EKX55482.1 - 0.32 11.5 3.3 0.34 11.4 0.8 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) EF-hand_7 PF13499.6 EKX55483.1 - 2e-14 53.8 5.1 5.3e-07 30.0 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EKX55483.1 - 1.3e-12 46.3 7.2 1.8e-06 27.1 0.0 4.4 4 1 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 EKX55483.1 - 2.1e-12 45.9 1.8 1.4e-06 27.7 0.0 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 EKX55483.1 - 2.4e-09 36.3 3.2 1.1e-05 24.7 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EKX55483.1 - 1.1e-08 34.7 3.8 0.00055 19.7 0.0 3.5 2 2 1 3 3 3 2 EF-hand domain pair MutL_C PF08676.11 EKX55483.1 - 0.04 13.7 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 MutL C terminal dimerisation domain CCD48 PF15799.5 EKX55483.1 - 0.083 11.2 0.0 0.11 10.8 0.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 LRR_6 PF13516.6 EKX55484.1 - 6.2e-13 47.7 6.7 0.39 10.9 0.0 8.1 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.7 EKX55484.1 - 2.6e-06 27.7 2.2 0.67 10.5 0.0 5.4 3 1 3 6 6 6 4 Leucine Rich repeats (2 copies) DUF4476 PF14771.6 EKX55484.1 - 0.00018 21.8 0.3 0.006 16.9 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4476) Glyco_transf_41 PF13844.6 EKX55485.1 - 3.4e-66 223.6 0.0 2.9e-36 124.9 0.0 2.2 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_9 PF13371.6 EKX55485.1 - 0.0015 18.6 0.0 2.5 8.3 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX55485.1 - 0.012 15.8 0.0 5.7 7.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat FeoC PF09012.10 EKX55485.1 - 0.061 13.4 0.1 0.25 11.5 0.1 2.0 1 0 0 1 1 1 0 FeoC like transcriptional regulator TPR_2 PF07719.17 EKX55485.1 - 0.065 13.4 0.0 26 5.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat K_channel_TID PF07941.11 EKX55485.1 - 2.7 8.5 6.8 6.5 7.3 6.8 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Tetraspanin PF00335.20 EKX55486.1 - 7.7e-07 29.1 13.6 2.2e-05 24.3 7.4 2.1 1 1 1 2 2 2 2 Tetraspanin family DUF202 PF02656.15 EKX55486.1 - 0.089 13.2 1.0 1.4 9.4 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF202) MAD PF05557.13 EKX55487.1 - 7e-14 51.1 16.7 2e-12 46.4 0.2 2.1 1 1 1 2 2 2 2 Mitotic checkpoint protein CALCOCO1 PF07888.11 EKX55487.1 - 1.9e-05 23.8 16.3 2.9e-05 23.2 10.0 2.1 2 0 0 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like Cast PF10174.9 EKX55487.1 - 0.00017 20.0 19.6 0.0015 16.9 15.9 2.7 2 1 0 2 2 2 1 RIM-binding protein of the cytomatrix active zone TMF_TATA_bd PF12325.8 EKX55487.1 - 0.0007 19.8 13.3 0.0007 19.8 13.3 3.2 2 2 1 3 3 3 1 TATA element modulatory factor 1 TATA binding SlyX PF04102.12 EKX55487.1 - 0.0023 18.5 16.8 0.24 12.0 0.3 4.3 4 0 0 4 4 4 2 SlyX Fib_alpha PF08702.10 EKX55487.1 - 0.0023 18.1 10.4 0.67 10.1 2.1 3.2 2 1 1 3 3 3 2 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 EKX55487.1 - 0.011 15.1 11.9 0.59 9.4 7.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TMF_DNA_bd PF12329.8 EKX55487.1 - 0.017 15.1 1.5 0.017 15.1 1.5 5.0 4 1 1 5 5 5 0 TATA element modulatory factor 1 DNA binding NEXCaM_BD PF16644.5 EKX55487.1 - 0.02 15.1 0.9 0.056 13.7 0.9 1.8 1 0 0 1 1 1 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin PKcGMP_CC PF16808.5 EKX55487.1 - 0.035 14.0 0.6 0.035 14.0 0.6 4.8 3 1 2 6 6 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase GP24_25 PF17388.2 EKX55487.1 - 0.036 14.0 1.8 0.058 13.4 0.1 2.1 2 1 1 3 3 3 0 Tail assembly gene products 24 & 25 XLF PF09302.11 EKX55487.1 - 0.044 14.0 9.0 0.15 12.2 0.4 2.9 2 1 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Spc7 PF08317.11 EKX55487.1 - 0.058 12.3 24.7 0.69 8.7 5.2 3.3 2 1 1 3 3 3 0 Spc7 kinetochore protein Fez1 PF06818.15 EKX55487.1 - 0.078 13.4 20.0 0.24 11.9 10.6 3.0 1 1 1 2 2 2 0 Fez1 FlaC_arch PF05377.11 EKX55487.1 - 0.087 13.2 8.2 1.1 9.7 0.2 4.0 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF5082 PF16888.5 EKX55487.1 - 0.092 13.0 15.0 0.35 11.2 0.8 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) NPV_P10 PF05531.12 EKX55487.1 - 0.19 12.2 12.0 2.8 8.5 0.4 3.8 2 1 2 5 5 4 0 Nucleopolyhedrovirus P10 protein GIT_CC PF16559.5 EKX55487.1 - 0.25 11.2 7.0 7.6 6.5 0.2 3.8 2 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Cep57_CLD_2 PF14197.6 EKX55487.1 - 0.6 10.2 28.8 0.79 9.9 4.5 5.6 4 1 1 5 5 5 0 Centrosome localisation domain of PPC89 FAM76 PF16046.5 EKX55487.1 - 0.85 8.9 16.7 4.4 6.6 12.5 3.0 2 1 1 3 3 3 0 FAM76 protein DUF4201 PF13870.6 EKX55487.1 - 1.5 8.6 25.9 0.56 9.9 5.0 4.1 3 1 2 5 5 5 0 Domain of unknown function (DUF4201) DUF16 PF01519.16 EKX55487.1 - 1.7 9.2 14.9 2.5 8.6 2.3 3.7 1 1 2 3 3 3 0 Protein of unknown function DUF16 Csm1_N PF18504.1 EKX55487.1 - 2.1 8.7 26.1 0.49 10.8 0.8 5.2 5 1 0 5 5 5 0 Csm1 N-terminal domain DASH_Dam1 PF08653.10 EKX55487.1 - 2.2 8.1 5.3 42 4.0 0.1 3.9 4 0 0 4 4 4 0 DASH complex subunit Dam1 DUF1811 PF08838.10 EKX55487.1 - 2.6 8.4 6.9 0.24 11.7 0.8 2.5 2 1 1 3 3 1 0 Protein of unknown function (DUF1811) Prominin PF05478.11 EKX55487.1 - 2.6 5.9 5.4 2.6 5.9 3.9 1.7 1 1 0 1 1 1 0 Prominin FlxA PF14282.6 EKX55487.1 - 3.7 7.6 20.3 1.7 8.6 2.7 3.7 2 2 1 3 3 3 0 FlxA-like protein DUF4200 PF13863.6 EKX55487.1 - 6.3 7.2 26.1 0.14 12.6 1.8 3.9 3 1 0 4 4 4 0 Domain of unknown function (DUF4200) Aminotran_1_2 PF00155.21 EKX55489.1 - 1.1e-82 278.1 0.0 1.3e-82 277.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1345 PF07077.11 EKX55490.1 - 0.027 14.2 0.2 0.033 13.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) DUF3474 PF11960.8 EKX55490.1 - 0.084 13.1 0.0 0.096 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) PfkB PF00294.24 EKX55492.1 - 4.1e-38 131.4 0.0 2.4e-37 128.9 0.0 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phosphorylase PF00343.20 EKX55493.1 - 4.4e-296 983.9 0.1 5.6e-296 983.5 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase DUF3301 PF11743.8 EKX55494.1 - 0.022 14.4 0.1 0.028 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) SDA1 PF05285.12 EKX55495.1 - 0.00013 21.5 9.8 0.00016 21.3 9.8 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 EKX55495.1 - 0.0041 15.4 10.2 0.0045 15.3 10.2 1.1 1 0 0 1 1 1 1 Nop14-like family CENP-B_dimeris PF09026.10 EKX55495.1 - 0.016 15.6 0.4 0.016 15.6 0.4 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PTPRCAP PF15713.5 EKX55495.1 - 0.017 15.4 10.5 0.017 15.4 10.5 1.6 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated BUD22 PF09073.10 EKX55495.1 - 0.038 13.3 19.8 0.064 12.6 19.8 1.3 1 0 0 1 1 1 0 BUD22 Herpes_LMP1 PF05297.11 EKX55495.1 - 0.37 9.9 9.1 0.59 9.3 9.1 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Sporozoite_P67 PF05642.11 EKX55495.1 - 1.1 7.2 12.3 1.5 6.8 12.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RNA_polI_A34 PF08208.11 EKX55495.1 - 2.4 8.2 12.8 0.7 9.9 9.3 1.7 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 SpoIIIAH PF12685.7 EKX55495.1 - 6.8 6.5 11.5 14 5.5 11.5 1.7 1 1 0 1 1 1 0 SpoIIIAH-like protein Bac_rhodopsin PF01036.18 EKX55497.1 - 1.2e-37 129.7 17.2 1.5e-37 129.4 17.2 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.6 EKX55497.1 - 0.95 9.1 5.5 8.2 6.0 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) CDP-OH_P_transf PF01066.21 EKX55497.1 - 4.4 8.2 7.2 97 3.8 7.2 2.9 1 1 0 1 1 1 0 CDP-alcohol phosphatidyltransferase NAGPA PF09992.9 EKX55498.1 - 0.00053 20.2 0.0 0.0009 19.5 0.0 1.4 1 1 0 1 1 1 1 Phosphodiester glycosidase YHYH PF14240.6 EKX55500.1 - 6.8e-08 32.7 3.3 0.00011 22.2 0.0 2.9 1 1 1 2 2 2 2 YHYH protein PA14 PF07691.12 EKX55501.1 - 3.1e-76 254.2 7.7 4.7e-19 68.6 0.0 9.7 9 0 0 9 9 9 8 PA14 domain FG-GAP PF01839.23 EKX55501.1 - 1.1e-25 89.4 28.8 3.8e-06 26.9 1.3 6.9 6 0 0 6 6 6 6 FG-GAP repeat VCBS PF13517.6 EKX55501.1 - 2.2e-15 57.0 10.2 7e-06 26.5 0.0 6.0 5 0 0 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Filamin PF00630.19 EKX55501.1 - 4.7e-14 53.1 0.1 0.096 13.5 0.0 9.7 10 0 0 10 10 10 2 Filamin/ABP280 repeat GLEYA PF10528.9 EKX55501.1 - 0.00011 22.5 11.1 16 6.0 0.0 8.4 8 0 0 8 8 8 2 GLEYA domain FG-GAP_2 PF14312.6 EKX55501.1 - 0.088 13.1 15.1 0.22 11.8 2.0 4.7 4 0 0 4 4 4 0 FG-GAP repeat Y_Y_Y PF07495.13 EKX55501.1 - 0.099 12.6 4.5 1.2 9.2 0.0 4.6 4 0 0 4 4 4 0 Y_Y_Y domain Multi_Drug_Res PF00893.19 EKX55502.1 - 0.054 14.2 0.1 0.071 13.8 0.1 1.2 1 0 0 1 1 1 0 Small Multidrug Resistance protein Rhomboid PF01694.22 EKX55503.1 - 9.6e-18 64.6 3.4 1.5e-17 64.0 3.4 1.3 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 EKX55503.1 - 0.0048 17.4 0.9 0.0067 17.0 0.5 1.6 1 1 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) FPN1 PF06963.12 EKX55504.1 - 1.8e-36 125.6 3.9 2.6e-36 125.1 3.9 1.2 1 0 0 1 1 1 1 Ferroportin1 (FPN1) MFS_2 PF13347.6 EKX55504.1 - 1.2e-05 24.1 10.8 1.9e-05 23.4 5.8 2.1 2 0 0 2 2 2 2 MFS/sugar transport protein Polyketide_cyc2 PF10604.9 EKX55505.1 - 0.0002 21.6 0.3 0.00032 21.0 0.3 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport THF_DHG_CYH_C PF02882.19 EKX55506.1 - 2.3e-36 124.5 1.0 3.2e-36 124.0 1.0 1.1 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EKX55506.1 - 3e-12 46.8 0.0 5.4e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Glyco_transf_6 PF03414.13 EKX55507.1 - 1.2e-10 40.7 0.0 9.1e-10 37.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 6 BiPBP_C PF06832.12 EKX55507.1 - 0.00053 20.0 0.0 0.0014 18.6 0.0 1.7 1 0 0 1 1 1 1 Penicillin-Binding Protein C-terminus Family Big_7 PF17957.1 EKX55507.1 - 0.0036 18.0 0.0 0.0074 17.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial Ig domain Ank_2 PF12796.7 EKX55509.1 - 2.6e-21 76.0 0.0 3e-11 43.8 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EKX55509.1 - 1.4e-18 66.4 0.2 0.0016 18.8 0.0 4.7 4 1 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EKX55509.1 - 9.2e-18 64.4 0.2 1.2e-07 32.1 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX55509.1 - 5.9e-16 58.3 0.5 0.00026 21.2 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EKX55509.1 - 7.7e-16 56.6 0.4 0.014 15.8 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat AFG1_ATPase PF03969.16 EKX55510.1 - 8.8e-65 219.0 0.0 1.2e-64 218.5 0.0 1.1 1 0 0 1 1 1 1 AFG1-like ATPase AAA_22 PF13401.6 EKX55510.1 - 7.4e-05 23.1 0.4 0.0021 18.4 0.4 2.5 1 1 0 1 1 1 1 AAA domain Bac_DnaA PF00308.18 EKX55510.1 - 7.9e-05 22.6 0.0 0.00061 19.7 0.0 2.1 2 0 0 2 2 2 1 Bacterial dnaA protein AAA PF00004.29 EKX55510.1 - 0.00024 21.5 0.0 0.00061 20.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX55510.1 - 0.00068 20.1 0.3 0.25 11.7 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EKX55510.1 - 0.00093 19.2 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EKX55510.1 - 0.073 13.6 0.1 2.5 8.6 0.0 2.4 1 1 0 2 2 2 0 ABC transporter AAA_19 PF13245.6 EKX55510.1 - 0.15 12.4 1.3 15 5.9 0.2 3.0 2 1 1 3 3 3 0 AAA domain AAA_5 PF07728.14 EKX55510.1 - 0.17 11.8 0.1 0.72 9.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ResIII PF04851.15 EKX55510.1 - 0.21 11.5 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NYN PF01936.18 EKX55511.1 - 2.7e-16 60.3 0.0 7.1e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 NYN domain PIN7 PF18475.1 EKX55511.1 - 0.082 13.5 0.1 0.27 11.9 0.0 1.9 2 0 0 2 2 2 0 PIN domain CPSF100_C PF13299.6 EKX55511.1 - 0.23 11.7 1.2 0.45 10.7 0.1 2.1 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal SpoU_methylase PF00588.19 EKX55512.1 - 1.3e-22 80.5 0.0 9.4e-21 74.5 0.0 2.5 2 0 0 2 2 2 2 SpoU rRNA Methylase family NOA36 PF06524.12 EKX55513.1 - 0.053 12.9 9.3 0.13 11.5 9.3 1.7 1 0 0 1 1 1 0 NOA36 protein PALB2_WD40 PF16756.5 EKX55513.1 - 0.062 12.2 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain ApoO PF09769.9 EKX55513.1 - 0.31 11.0 2.0 1.5 8.8 0.4 2.7 2 0 0 2 2 2 0 Apolipoprotein O PBP1_TM PF14812.6 EKX55513.1 - 1.5 9.3 11.6 0.26 11.7 6.8 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.6 EKX55513.1 - 2 8.7 23.4 0.67 10.2 7.8 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.10 EKX55513.1 - 2.5 8.6 15.7 8.9 6.8 15.7 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HALZ PF02183.18 EKX55513.1 - 2.6 8.3 13.3 0.17 12.1 2.1 3.9 3 1 0 3 3 3 0 Homeobox associated leucine zipper RCC1 PF00415.18 EKX55514.1 - 8.3e-53 176.8 11.1 4.4e-10 40.0 0.1 6.6 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EKX55514.1 - 5.9e-30 102.4 28.3 7.3e-07 28.8 0.3 8.4 8 1 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat CHB_HEX_C_1 PF13290.6 EKX55514.1 - 2e-28 98.2 0.0 1.2e-06 28.5 0.0 4.3 4 0 0 4 4 4 4 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 EKX55514.1 - 2.6e-24 85.1 0.0 2.5e-05 24.3 0.0 4.3 4 0 0 4 4 4 4 Fn3 associated CHB_HEX_C PF03174.13 EKX55514.1 - 0.024 14.6 0.0 0.45 10.5 0.0 2.7 3 0 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain AAA PF00004.29 EKX55516.1 - 2.5e-14 53.8 0.0 3.1e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EKX55516.1 - 1.6e-05 24.9 0.0 2.5e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EKX55516.1 - 1.8e-05 25.0 0.0 0.00074 19.8 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EKX55516.1 - 1.8e-05 25.2 0.0 6.2e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EKX55516.1 - 2e-05 25.1 0.0 4.5e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EKX55516.1 - 3.1e-05 24.2 0.1 3.4e-05 24.1 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EKX55516.1 - 5.8e-05 23.1 0.0 6.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 EKX55516.1 - 0.00011 22.2 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 EKX55516.1 - 0.00012 21.9 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 EKX55516.1 - 0.0006 19.6 0.1 0.005 16.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EKX55516.1 - 0.0025 18.1 0.1 0.005 17.1 0.1 1.4 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EKX55516.1 - 0.0033 17.8 0.0 0.0075 16.6 0.0 1.7 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.12 EKX55516.1 - 0.0035 17.3 0.0 0.02 14.8 0.0 1.9 1 1 1 2 2 2 1 NACHT domain AAA_11 PF13086.6 EKX55516.1 - 0.0061 16.4 0.2 0.0099 15.7 0.1 1.3 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EKX55516.1 - 0.0098 15.4 0.2 0.17 11.4 0.1 2.1 2 0 0 2 2 2 1 PhoH-like protein AAA_7 PF12775.7 EKX55516.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 EKX55516.1 - 0.012 15.2 0.1 0.034 13.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EKX55516.1 - 0.013 14.8 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EKX55516.1 - 0.014 15.1 0.3 0.025 14.3 0.3 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.27 EKX55516.1 - 0.024 15.2 0.0 0.05 14.1 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 EKX55516.1 - 0.025 14.3 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EKX55516.1 - 0.031 14.3 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 EKX55516.1 - 0.039 13.8 0.3 0.39 10.6 0.1 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 EKX55516.1 - 0.041 13.1 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.6 EKX55516.1 - 0.041 14.3 0.1 0.041 14.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EKX55516.1 - 0.057 13.7 0.3 0.1 12.9 0.3 1.5 1 1 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 EKX55516.1 - 0.076 13.3 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain NTPase_1 PF03266.15 EKX55516.1 - 0.1 12.5 0.1 0.29 11.0 0.1 1.7 2 0 0 2 2 2 0 NTPase AAA_6 PF12774.7 EKX55516.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region TIP49 PF06068.13 EKX55516.1 - 0.11 11.6 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Viral_helicase1 PF01443.18 EKX55516.1 - 0.14 11.9 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 EKX55516.1 - 0.15 11.8 0.1 0.25 11.0 0.1 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain cobW PF02492.19 EKX55516.1 - 0.15 11.7 0.1 0.31 10.6 0.0 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 EKX55516.1 - 0.18 11.0 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) dNK PF01712.19 EKX55516.1 - 0.19 11.6 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase DUF29 PF01724.16 EKX55517.1 - 0.069 13.4 0.9 0.19 11.9 0.3 1.9 1 1 1 2 2 2 0 Domain of unknown function DUF29 Glycos_transf_2 PF00535.26 EKX55518.1 - 3.4e-08 33.5 0.0 7e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_1_4 PF13692.6 EKX55518.1 - 0.0041 17.5 0.0 0.05 14.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EKX55518.1 - 0.0043 16.6 0.0 0.067 12.7 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 TPR_2 PF07719.17 EKX55519.1 - 1e-17 62.8 12.2 0.00033 20.5 0.1 8.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 EKX55519.1 - 1.2e-11 44.7 15.2 0.0007 19.8 0.1 6.5 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 EKX55519.1 - 6.8e-09 35.2 9.6 0.17 12.2 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 EKX55519.1 - 9.9e-09 34.7 18.3 1.8e-05 24.4 0.1 6.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 EKX55519.1 - 1.4e-08 35.3 14.7 0.073 13.7 0.1 6.9 5 2 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX55519.1 - 2.2e-05 24.9 14.7 0.22 12.4 0.1 7.6 7 2 0 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX55519.1 - 2.9e-05 24.1 7.0 0.0099 16.2 0.1 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 EKX55519.1 - 7.8e-05 23.1 14.9 0.00051 20.5 0.2 5.1 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX55519.1 - 0.00018 21.6 4.7 0.59 10.3 0.1 4.5 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX55519.1 - 0.00028 20.7 14.8 0.014 15.3 0.1 4.8 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 EKX55519.1 - 0.033 14.1 12.9 8.1 6.5 0.1 6.4 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EKX55519.1 - 0.04 14.6 11.8 22 6.0 0.2 6.8 7 2 0 7 7 5 0 Tetratricopeptide repeat PPR PF01535.20 EKX55519.1 - 0.051 13.8 1.4 28 5.2 0.0 4.9 4 1 1 5 5 5 0 PPR repeat TPR_11 PF13414.6 EKX55519.1 - 7 6.4 8.6 8.2 6.2 0.2 4.3 4 1 0 4 4 4 0 TPR repeat HhH-GPD PF00730.25 EKX55520.1 - 5.1e-06 26.9 0.0 1.2e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Casein PF00363.18 EKX55520.1 - 0.0084 16.5 0.0 0.015 15.6 0.0 1.3 1 0 0 1 1 1 1 Casein RHH_1 PF01402.21 EKX55520.1 - 0.024 14.5 1.7 0.042 13.8 0.7 2.0 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family HHH_5 PF14520.6 EKX55520.1 - 0.14 12.8 0.0 29 5.4 0.0 2.9 1 1 2 3 3 3 0 Helix-hairpin-helix domain MFS_1 PF07690.16 EKX55521.1 - 5.3e-39 134.1 38.3 7.2e-39 133.7 38.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EKX55521.1 - 2e-36 125.9 24.0 2.3e-36 125.6 24.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Folate_carrier PF01770.18 EKX55521.1 - 0.00015 20.7 3.1 0.0002 20.2 3.1 1.2 1 0 0 1 1 1 1 Reduced folate carrier TIL PF01826.17 EKX55522.1 - 0.0029 17.8 11.8 0.23 11.7 0.6 3.9 3 0 0 3 3 3 2 Trypsin Inhibitor like cysteine rich domain TPR_11 PF13414.6 EKX55522.1 - 0.013 15.2 4.5 2.1 8.1 0.1 2.9 3 0 0 3 3 3 0 TPR repeat EGF_MSP1_1 PF12946.7 EKX55522.1 - 0.036 14.1 8.3 1.6 8.8 1.0 2.7 2 0 0 2 2 2 0 MSP1 EGF domain 1 cEGF PF12662.7 EKX55522.1 - 0.11 12.4 8.1 1.6 8.7 1.1 2.8 2 0 0 2 2 2 0 Complement Clr-like EGF-like EB PF01683.18 EKX55522.1 - 0.4 11.0 7.7 11 6.4 0.9 3.4 2 0 0 2 2 2 0 EB module TPR_16 PF13432.6 EKX55522.1 - 0.4 11.4 8.5 8.6 7.1 0.4 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EKX55522.1 - 0.81 10.0 6.8 15 6.0 0.4 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Rho_GDI PF02115.17 EKX55522.1 - 1.2 8.9 19.6 0.72 9.6 0.1 3.7 3 0 0 3 3 3 0 RHO protein GDP dissociation inhibitor SHE3 PF17078.5 EKX55524.1 - 3.2e-05 23.7 10.6 3.2e-05 23.7 10.6 4.8 2 1 3 6 6 6 4 SWI5-dependent HO expression protein 3 FlxA PF14282.6 EKX55524.1 - 0.2 11.7 0.1 0.2 11.7 0.1 5.4 1 1 2 4 4 4 0 FlxA-like protein Halo_GVPC PF05465.13 EKX55524.1 - 0.26 11.6 4.2 1.4e+02 2.8 0.0 4.8 5 0 0 5 5 5 0 Halobacterial gas vesicle protein C (GVPC) repeat ApoC-I PF04691.12 EKX55524.1 - 0.65 10.0 7.4 2.3 8.2 0.4 4.2 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) CLZ PF16526.5 EKX55524.1 - 1.1 9.7 70.9 0.17 12.3 4.6 7.4 4 3 5 9 9 9 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1664 PF07889.12 EKX55524.1 - 4.9 7.2 34.7 0.21 11.6 2.3 6.0 2 1 4 7 7 7 0 Protein of unknown function (DUF1664) DUF5344 PF17279.2 EKX55524.1 - 5.4 7.7 27.5 0.12 12.9 2.9 6.1 3 3 3 6 6 6 0 Family of unknown function (DUF5344) DUF3584 PF12128.8 EKX55524.1 - 8.1 3.8 61.0 3.5 5.0 54.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) LRR_6 PF13516.6 EKX55525.1 - 5.8e-13 47.8 5.5 0.0014 18.6 0.0 4.4 5 0 0 5 5 5 3 Leucine Rich repeat FTH PF01827.27 EKX55525.1 - 0.24 11.2 1.8 0.31 10.8 0.1 2.1 2 1 0 2 2 2 0 FTH domain FumaraseC_C PF10415.9 EKX55525.1 - 0.96 9.9 3.3 16 6.0 0.1 3.5 3 1 1 4 4 4 0 Fumarase C C-terminus Tugs PF17840.1 EKX55525.1 - 2.5 8.4 0.0 2.5 8.4 0.0 3.3 4 0 0 4 4 4 0 Tethering Ubl4a to BAGS domain zf-trcl PF13451.6 EKX55526.1 - 1.4e-20 72.9 7.1 1.4e-20 72.9 7.1 2.0 2 0 0 2 2 2 1 Probable zinc-ribbon domain zf_CCCH_4 PF18345.1 EKX55526.1 - 1.8e-06 27.8 3.9 4.4e-06 26.6 3.9 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 EKX55526.1 - 3e-06 27.0 1.8 6.8e-06 25.9 1.8 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EKX55526.1 - 5.6e-06 26.0 1.2 1.2e-05 25.0 1.2 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger Mpp10 PF04006.12 EKX55526.1 - 0.0071 14.8 43.2 0.0077 14.7 43.2 1.0 1 0 0 1 1 1 1 Mpp10 protein CDC45 PF02724.14 EKX55526.1 - 0.64 8.2 33.3 0.75 8.0 33.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 EKX55526.1 - 2.7 6.7 24.8 2.8 6.6 24.8 1.1 1 0 0 1 1 1 0 Presenilin CDC27 PF09507.10 EKX55526.1 - 3.1 7.1 41.1 4 6.7 41.1 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF4045 PF13254.6 EKX55526.1 - 5.7 6.5 24.1 6 6.4 24.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) zf-CCCH PF00642.24 EKX55528.1 - 1.7e-05 24.6 3.6 2.8e-05 23.9 3.6 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EKX55528.1 - 0.00071 19.5 4.6 0.0012 18.8 4.6 1.4 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 EKX55528.1 - 0.0039 17.9 0.0 0.25 12.0 0.0 2.8 2 0 0 2 2 2 1 Torus domain DUF5407 PF17401.2 EKX55528.1 - 0.099 12.9 0.2 0.26 11.6 0.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5407) EamA PF00892.20 EKX55529.1 - 1.3e-15 57.8 22.1 2.7e-11 43.8 6.1 2.8 2 1 0 2 2 2 2 EamA-like transporter family ECD PF18432.1 EKX55529.1 - 0.19 11.7 0.0 0.36 10.8 0.0 1.3 1 0 0 1 1 1 0 Extracellular Cadherin domain HECT PF00632.25 EKX55530.1 - 9.5e-75 251.9 0.1 2.6e-74 250.5 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Ank_2 PF12796.7 EKX55531.1 - 2e-14 53.9 0.0 2.4e-13 50.5 0.0 2.7 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EKX55531.1 - 3.6e-14 51.5 0.1 0.00017 21.8 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EKX55531.1 - 3.7e-11 43.3 0.0 3.1e-07 30.8 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EKX55531.1 - 6.8e-11 42.2 0.1 5e-07 29.9 0.0 3.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EKX55531.1 - 5.3e-09 36.1 0.0 2.8e-05 24.4 0.0 4.1 3 1 1 4 4 4 2 Ankyrin repeat IL34 PF15036.6 EKX55531.1 - 0.038 14.0 0.1 0.073 13.1 0.1 1.4 1 0 0 1 1 1 0 Interleukin 34 Imm58 PF15581.6 EKX55531.1 - 0.068 13.3 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 58 SPG48 PF14764.6 EKX55531.1 - 0.16 12.4 1.8 4.4 7.8 1.8 2.6 1 1 0 1 1 1 0 AP-5 complex subunit, vesicle trafficking RNA_pol_Rpb1_2 PF00623.20 EKX55532.1 - 6.1e-71 238.0 0.1 1.1e-70 237.1 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 EKX55532.1 - 1.4e-69 234.9 0.1 2.4e-69 234.1 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EKX55532.1 - 8e-66 222.2 0.1 1.4e-65 221.4 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_3 PF04983.18 EKX55532.1 - 1.3e-29 103.1 0.0 4.2e-29 101.5 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EKX55532.1 - 5.5e-27 93.8 0.0 3.7e-26 91.2 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 KASH_CCD PF14662.6 EKX55533.1 - 0.0028 17.5 1.3 0.0058 16.5 1.3 1.5 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Med9 PF07544.13 EKX55533.1 - 0.075 13.1 2.1 0.19 11.8 2.1 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF4890 PF16231.5 EKX55533.1 - 0.079 13.5 4.4 0.43 11.1 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4890) DUF4011 PF13195.6 EKX55533.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) ApoLp-III PF07464.11 EKX55533.1 - 0.71 10.0 4.1 29 4.7 0.6 3.1 2 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DUF4337 PF14235.6 EKX55533.1 - 0.85 9.7 5.9 0.35 11.0 2.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) YkyA PF10368.9 EKX55533.1 - 0.94 9.1 7.7 0.19 11.4 1.5 2.2 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein TBP PF00352.21 EKX55535.1 - 2.6e-10 40.1 0.0 0.00065 19.6 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) HMG_box_2 PF09011.10 EKX55535.1 - 0.031 14.8 0.0 0.064 13.9 0.0 1.5 1 0 0 1 1 1 0 HMG-box domain DUF936 PF06075.12 EKX55535.1 - 0.17 10.8 10.1 0.24 10.3 10.1 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Vfa1 PF08432.10 EKX55535.1 - 0.37 11.1 3.0 0.73 10.1 3.0 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Dynamin_N PF00350.23 EKX55536.1 - 8.2e-07 29.2 1.0 2.5e-06 27.7 0.1 2.3 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EKX55536.1 - 0.0031 17.6 0.0 0.0072 16.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EKX55536.1 - 0.053 13.7 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EKX55536.1 - 0.075 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Sarcoglycan_2 PF05510.13 EKX55536.1 - 0.091 11.5 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon DUF4618 PF15397.6 EKX55537.1 - 0.0027 17.2 6.2 0.21 11.0 0.4 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4618) Prominin PF05478.11 EKX55537.1 - 0.0044 15.1 0.7 0.0056 14.7 0.7 1.1 1 0 0 1 1 1 1 Prominin KxDL PF10241.9 EKX55537.1 - 0.012 15.9 2.8 0.021 15.1 0.8 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein HBM PF16591.5 EKX55537.1 - 0.019 14.4 0.4 0.11 12.0 0.1 1.9 1 1 0 1 1 1 0 Helical bimodular sensor domain MCPsignal PF00015.21 EKX55537.1 - 0.047 13.5 0.3 0.076 12.8 0.3 1.4 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Sec8_exocyst PF04048.14 EKX55537.1 - 0.051 13.5 1.7 0.24 11.3 1.7 2.1 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain DUF1664 PF07889.12 EKX55537.1 - 0.056 13.5 2.9 0.17 11.9 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) OmpH PF03938.14 EKX55537.1 - 0.13 12.6 8.0 0.22 11.8 4.0 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) TACC_C PF05010.14 EKX55537.1 - 0.25 11.1 8.3 0.34 10.7 8.3 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF4200 PF13863.6 EKX55537.1 - 0.25 11.7 12.9 0.13 12.6 1.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Fib_alpha PF08702.10 EKX55537.1 - 0.31 11.2 2.0 1.1 9.4 2.0 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family HsdM_N PF12161.8 EKX55537.1 - 0.47 11.1 6.6 0.99 10.0 6.6 1.5 1 1 0 1 1 1 0 HsdM N-terminal domain TMPIT PF07851.13 EKX55537.1 - 0.55 9.4 4.1 0.19 11.0 1.5 1.4 2 0 0 2 2 2 0 TMPIT-like protein V-SNARE PF05008.15 EKX55537.1 - 3.3 8.1 7.0 40 4.7 0.2 3.4 1 1 2 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Dicty_CAR PF05462.11 EKX55538.1 - 4e-09 36.0 11.1 5.2e-09 35.7 11.1 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7TM_GPCR_Srsx PF10320.9 EKX55538.1 - 0.00074 19.0 2.0 0.00086 18.8 2.0 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx GPR_Gpa2_C PF11970.8 EKX55538.1 - 0.0067 16.5 0.4 0.0067 16.5 0.4 2.1 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Anoctamin PF04547.12 EKX55539.1 - 2e-70 237.9 13.4 2.5e-70 237.6 13.4 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 EKX55539.1 - 1.7e-07 31.2 0.9 2.8e-06 27.2 0.1 2.4 2 0 0 2 2 2 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Ctr PF04145.15 EKX55539.1 - 0.0046 17.6 0.0 0.012 16.2 0.0 1.7 1 0 0 1 1 1 1 Ctr copper transporter family COX16 PF14138.6 EKX55540.1 - 3.4e-09 37.1 0.7 8.2e-09 35.9 0.7 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 C2 PF00168.30 EKX55541.1 - 1.8e-13 50.7 0.1 1.9e-13 50.6 0.1 1.0 1 0 0 1 1 1 1 C2 domain IPK PF03770.16 EKX55542.1 - 8.3e-19 68.2 0.0 1.3e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase SDF PF00375.18 EKX55543.1 - 3.5e-113 378.6 31.0 3.9e-113 378.4 31.0 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family TPR_1 PF00515.28 EKX55544.1 - 2.4e-18 65.1 6.1 2.4e-05 23.9 0.3 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX55544.1 - 2.3e-14 52.2 4.8 8.8e-05 22.3 0.7 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX55544.1 - 1.2e-09 37.7 1.2 0.00011 21.8 0.0 3.0 2 1 1 3 3 3 3 TPR repeat TPR_9 PF13371.6 EKX55544.1 - 1.7e-09 37.7 2.9 1.3e-07 31.7 1.4 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EKX55544.1 - 1.8e-09 37.6 0.8 0.00045 20.8 1.5 2.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX55544.1 - 2.3e-09 37.6 4.3 0.00049 20.5 2.3 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 EKX55544.1 - 3.5e-09 36.4 1.4 0.0018 18.5 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX55544.1 - 8e-09 35.0 3.2 0.0052 16.9 0.2 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX55544.1 - 1.1e-07 31.7 1.4 6.3e-06 26.2 0.6 2.7 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 EKX55544.1 - 0.00022 21.4 2.9 0.00084 19.5 2.9 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EKX55544.1 - 0.00027 21.5 0.6 0.0055 17.3 2.1 2.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EKX55544.1 - 0.001 18.9 0.4 1.5 9.0 0.0 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_20 PF14561.6 EKX55544.1 - 0.0019 18.5 1.2 0.004 17.5 0.7 1.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EKX55544.1 - 0.0033 18.0 2.3 0.0071 16.9 0.5 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EKX55545.1 - 1.9e-21 74.9 1.0 2.5e-09 36.5 0.1 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EKX55545.1 - 8.5e-19 66.1 1.3 1.7e-08 34.0 0.1 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX55545.1 - 2.3e-10 40.0 0.1 6.8e-05 22.5 0.0 3.2 2 1 1 3 3 3 2 TPR repeat TPR_12 PF13424.6 EKX55545.1 - 3.4e-10 40.1 1.9 7.1e-06 26.2 0.4 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX55545.1 - 8e-08 31.9 0.3 3.5e-05 23.7 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EKX55545.1 - 2.6e-07 30.3 1.2 0.018 14.9 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EKX55545.1 - 5.1e-06 26.5 0.6 1.8e-05 24.8 0.1 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EKX55545.1 - 2.8e-05 24.2 0.1 0.0022 18.3 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EKX55545.1 - 5.5e-05 23.7 0.0 0.0031 18.1 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EKX55545.1 - 0.00011 22.7 0.7 0.14 13.0 0.1 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EKX55545.1 - 0.00012 22.5 0.2 0.41 11.2 0.1 2.3 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EKX55545.1 - 0.00039 20.3 0.5 0.21 11.7 0.0 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 EKX55545.1 - 0.0016 17.9 0.6 1.6 8.2 0.0 3.1 3 0 0 3 3 3 1 SHNi-TPR TPR_MalT PF17874.1 EKX55545.1 - 0.0024 17.3 1.1 0.01 15.2 1.1 1.7 1 1 0 1 1 1 1 MalT-like TPR region TPR_6 PF13174.6 EKX55545.1 - 0.02 15.5 0.0 0.16 12.7 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EKX55545.1 - 0.022 14.8 0.5 0.25 11.4 0.0 2.4 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.28 EKX55546.1 - 9.1e-10 37.9 13.3 0.15 12.0 0.0 6.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 EKX55546.1 - 3.1e-06 27.6 7.8 0.00018 22.0 0.4 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EKX55546.1 - 1.3e-05 25.0 8.4 0.57 10.5 0.2 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EKX55546.1 - 1.8e-05 24.5 16.3 0.088 13.0 0.0 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 EKX55546.1 - 3e-05 23.6 2.0 0.13 12.0 0.3 3.7 2 1 2 4 4 4 2 TPR repeat TPR_16 PF13432.6 EKX55546.1 - 0.00012 22.6 8.1 0.012 16.3 0.9 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EKX55546.1 - 0.0055 17.0 1.4 0.0055 17.0 1.4 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EKX55546.1 - 0.019 15.1 3.0 0.85 9.9 1.8 2.9 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EKX55546.1 - 0.029 14.5 6.0 0.13 12.4 0.6 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EKX55546.1 - 0.049 14.5 7.3 0.39 11.7 0.1 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 EKX55546.1 - 0.051 13.7 4.2 3.9 7.6 0.0 4.5 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain ParD_antitoxin PF03693.14 EKX55546.1 - 0.065 13.6 2.3 15 6.1 0.0 3.0 3 0 0 3 3 3 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH Fis1_TPR_C PF14853.6 EKX55546.1 - 0.1 12.7 2.4 20 5.4 0.1 3.8 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat adh_short PF00106.25 EKX55547.1 - 2e-16 60.0 0.0 4.6e-16 58.9 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EKX55547.1 - 7.9e-08 32.1 0.0 1.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EKX55547.1 - 6.4e-07 29.5 0.0 1.3e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 KR domain FSA_C PF10479.9 EKX55548.1 - 7.1 4.6 11.5 10 4.1 11.5 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus FSA_C PF10479.9 EKX55551.1 - 7.2 4.6 8.3 9 4.3 8.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus ATP-grasp_6 PF18419.1 EKX55552.1 - 0.017 14.7 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp-like domain MtrH PF02007.18 EKX55552.1 - 0.14 11.2 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit Sec39 PF08314.11 EKX55553.1 - 0.0089 14.5 0.4 0.011 14.2 0.4 1.1 1 0 0 1 1 1 1 Secretory pathway protein Sec39 AAA_14 PF13173.6 EKX55553.1 - 0.013 15.5 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2207 PF09972.9 EKX55554.1 - 0.0038 16.1 3.6 0.0039 16.0 3.6 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Pex24p PF06398.11 EKX55554.1 - 0.017 14.2 5.4 0.023 13.7 5.4 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Wzy_C PF04932.15 EKX55554.1 - 0.042 13.5 4.5 0.053 13.2 4.5 1.3 1 0 0 1 1 1 0 O-Antigen ligase Phage_holin_3_6 PF07332.11 EKX55554.1 - 0.091 12.8 18.8 0.14 12.2 18.8 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III EI24 PF07264.11 EKX55554.1 - 0.11 12.8 14.3 0.12 12.6 14.3 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) FA_desaturase PF00487.24 EKX55554.1 - 0.34 10.7 4.4 0.33 10.8 4.4 1.2 1 0 0 1 1 1 0 Fatty acid desaturase YfhO PF09586.10 EKX55554.1 - 1.2 7.3 9.2 1.2 7.3 9.2 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF4191 PF13829.6 EKX55554.1 - 2.3 7.5 6.8 2.4 7.4 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF2663 PF10864.8 EKX55554.1 - 9.4 6.7 9.2 17 5.8 9.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2663) AAA_25 PF13481.6 EKX55555.1 - 7.8e-07 28.9 0.1 2.8e-06 27.0 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EKX55555.1 - 7.8e-05 22.6 11.1 0.004 17.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EKX55555.1 - 0.018 15.3 0.9 0.068 13.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EKX55555.1 - 0.035 14.1 0.1 0.035 14.1 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EKX55555.1 - 0.088 12.3 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 EKX55555.1 - 0.099 13.1 0.0 0.54 10.7 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EKX55555.1 - 0.11 12.9 0.0 0.55 10.6 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 EKX55555.1 - 0.16 12.3 0.3 0.69 10.2 0.1 2.2 2 0 0 2 2 2 0 AAA domain FliD_C PF07195.12 EKX55555.1 - 2 7.8 6.2 4.7 6.5 6.2 1.6 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF1204 PF06721.11 EKX55555.1 - 6.1 6.2 13.9 11 5.4 13.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) DUF3450 PF11932.8 EKX55555.1 - 6.4 6.0 17.6 3.2 7.0 14.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 EKX55555.1 - 9.1 6.5 16.3 18 5.5 0.1 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family zf-CDGSH PF09360.10 EKX55556.1 - 3.3e-20 72.0 5.3 4.5e-11 42.8 0.6 2.1 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type AAA_25 PF13481.6 EKX55557.1 - 1.7e-06 27.7 2.7 2e-06 27.6 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 EKX55557.1 - 0.0036 17.1 0.0 0.0036 17.1 0.0 4.4 2 1 2 4 4 4 1 AAA domain AAA_22 PF13401.6 EKX55557.1 - 0.26 11.6 0.0 0.26 11.6 0.0 3.3 3 1 0 3 3 3 0 AAA domain zf-CDGSH PF09360.10 EKX55558.1 - 5.6e-17 61.7 7.6 3.4e-08 33.6 0.3 2.1 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type PAPS_reduct PF01507.19 EKX55559.1 - 2e-31 109.4 0.0 6.9e-31 107.6 0.0 1.9 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family Thioredoxin PF00085.20 EKX55559.1 - 9.8e-10 38.3 0.1 2.8e-09 36.9 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 EKX55559.1 - 0.00015 21.7 0.3 0.00029 20.7 0.0 1.5 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 EKX55559.1 - 0.00086 19.7 0.5 0.0043 17.5 0.2 2.3 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EKX55559.1 - 0.0027 18.0 0.0 0.0076 16.6 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 EKX55559.1 - 0.0028 17.8 0.0 0.0078 16.4 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_5 PF13743.6 EKX55559.1 - 0.029 14.0 0.0 0.063 12.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin ERp29_N PF07912.13 EKX55559.1 - 0.16 12.1 1.7 3.9 7.7 0.1 3.1 3 1 0 3 3 3 0 ERp29, N-terminal domain tRNA-synt_His PF13393.6 EKX55560.1 - 2.9e-48 164.7 0.0 4.4e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EKX55560.1 - 6.7e-15 55.0 0.2 1.5e-14 53.9 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EKX55560.1 - 2.5e-09 37.3 0.0 4.2e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon2 PF12745.7 EKX55560.1 - 0.0012 18.5 0.2 0.0012 18.5 0.2 1.6 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_2d PF01409.20 EKX55560.1 - 0.0081 15.7 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_His PF13393.6 EKX55561.1 - 2.1e-48 165.2 0.0 2.8e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EKX55561.1 - 3.5e-12 46.3 0.2 8.7e-12 45.0 0.2 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EKX55561.1 - 1.9e-09 37.7 0.0 2.9e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 EKX55561.1 - 0.0061 16.1 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Cryptophyte/Guillardia_theta/GCA_000315625.1_Guith1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Cryptophyte/Guillardia_theta/GCA_000315625.1_Guith1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Cryptophyte/Guillardia_theta/GCA_000315625.1_Guith1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Cryptophyte/Guillardia_theta/GCA_000315625.1_Guith1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 09:25:55 2019 # [ok]